# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF4108 PF13390.6 EAX64101.1 - 4.9e-50 169.2 7.8 5.4e-50 169.0 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX64102.1 - 2.8e-08 33.5 1.3 3.5e-08 33.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64102.1 - 0.0063 16.2 0.2 0.0068 16.1 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64102.1 - 0.052 13.3 0.1 0.13 12.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64102.1 - 0.13 12.2 0.3 1 9.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX64104.1 - 5e-07 29.4 2.0 8.1e-07 28.7 1.3 1.8 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64104.1 - 2.1e-05 24.8 0.2 0.00019 21.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64104.1 - 3.8e-05 23.5 0.3 0.33 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64104.1 - 0.00021 21.4 3.3 0.00047 20.2 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64104.1 - 0.00067 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64104.1 - 0.0017 18.2 0.7 0.0039 17.0 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64104.1 - 0.002 17.8 0.4 0.011 15.3 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64104.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX64104.1 - 0.062 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX64104.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX64104.1 - 0.098 13.1 0.1 0.78 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX64104.1 - 0.44 10.8 4.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX64105.1 - 2.7e-67 226.0 0.9 3.5e-67 225.6 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64105.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX64106.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64106.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX64106.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX64106.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX64106.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX64106.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX64106.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Trypan_PARP PF05887.11 EAX64107.1 - 0.073 13.1 9.7 0.11 12.4 9.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX64107.1 - 1.8 9.0 5.4 2.6 8.5 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 EAX64113.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX64113.1 - 0.14 12.9 5.8 15 6.8 0.2 3.6 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX64114.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64114.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF846 PF05832.12 EAX64115.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF4108 PF13390.6 EAX64117.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF257 PF03192.13 EAX64118.1 - 0.00097 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX64118.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2486 PF10667.9 EAX64120.1 - 0.12 12.5 29.2 0.12 12.6 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DNA_pol_B_2 PF03175.13 EAX64121.1 - 6.8e-21 74.7 3.5 1.1e-20 74.0 3.5 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX64123.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX64123.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX64124.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein FAS_N PF17828.1 EAX64126.1 - 0.017 15.1 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX64127.1 - 0.0001 22.7 0.5 0.00018 22.0 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64127.1 - 0.014 16.0 0.2 0.018 15.6 0.2 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX64127.1 - 0.057 13.4 0.3 0.078 13.0 0.3 1.3 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX64128.1 - 2.1e-57 193.1 4.0 2.4e-57 192.9 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX64128.1 - 0.11 11.6 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DAO_C PF16901.5 EAX64129.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF4106 PF13388.6 EAX64130.1 - 1.3e-41 143.2 4.1 1.5e-41 143.0 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) PTR PF12789.7 EAX64132.1 - 0.22 11.6 0.3 0.22 11.6 0.3 3.1 4 0 0 4 4 4 0 Phage tail repeat like TMP PF05017.14 EAX64133.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64134.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP YmaF PF12788.7 EAX64136.1 - 0.14 12.7 1.6 1.6 9.3 1.6 2.0 1 1 1 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX64136.1 - 0.55 10.5 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX64137.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF2939 PF11159.8 EAX64141.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX64141.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF2939 PF11159.8 EAX64143.1 - 0.025 15.0 0.2 0.035 14.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Tctex-1 PF03645.13 EAX64144.1 - 0.085 13.1 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Tctex-1 family HTH_32 PF13565.6 EAX64144.1 - 0.32 11.6 5.1 0.44 11.2 5.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain TSP_NTD PF17804.1 EAX64144.1 - 0.45 10.7 7.9 0.62 10.3 7.9 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Membralin PF09746.9 EAX64144.1 - 2.7 6.9 3.9 2.9 6.8 3.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 EAX64144.1 - 2.8 7.9 5.3 3 7.8 5.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_B_2 PF03175.13 EAX64145.1 - 5.9e-14 51.8 7.3 8.5e-14 51.3 3.9 2.0 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral PHM7_cyt PF14703.6 EAX64145.1 - 0.1 12.8 0.4 0.3 11.3 0.2 2.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Isy1 PF06246.12 EAX64145.1 - 0.11 12.0 0.7 0.22 11.0 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family DUF5106 PF17127.4 EAX64145.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Ank_2 PF12796.7 EAX64146.1 - 7.9e-39 132.1 6.0 8.9e-14 51.8 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX64146.1 - 3e-27 94.6 2.1 2.6e-10 40.6 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX64146.1 - 4.8e-23 80.9 0.2 1.9e-07 31.2 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX64146.1 - 6.3e-20 69.2 0.9 0.0087 16.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EAX64146.1 - 8.8e-19 67.0 1.9 0.0091 16.4 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat DUF1493 PF07377.12 EAX64147.1 - 0.015 15.8 0.9 0.027 14.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX64149.1 - 0.057 13.9 0.9 0.057 13.9 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64149.1 - 0.65 10.1 4.0 10 6.2 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein HD_2 PF12917.7 EAX64151.1 - 0.093 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Amidase02_C PF12123.8 EAX64153.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX64153.1 - 0.17 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX64154.1 - 9.8e-19 67.6 3.4 1.2e-18 67.2 3.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4107 PF13389.6 EAX64155.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF5365 PF17326.2 EAX64157.1 - 0.029 14.7 0.3 0.074 13.5 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX64157.1 - 0.033 14.5 0.5 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 PWI domain PSP PF04046.16 EAX64159.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP La PF05383.17 EAX64160.1 - 0.045 13.8 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 La domain DUF4378 PF14309.6 EAX64160.1 - 0.06 13.7 0.0 0.1 13.0 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) DUF5077 PF16871.5 EAX64161.1 - 0.064 13.1 3.2 0.087 12.7 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) PTR PF12789.7 EAX64163.1 - 2.3e-06 27.6 17.6 6.4e-06 26.1 0.2 5.5 4 2 2 6 6 6 2 Phage tail repeat like DUF4738 PF15889.5 EAX64163.1 - 0.0091 15.8 2.0 0.0091 15.8 2.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4738) DUF4795 PF16043.5 EAX64163.1 - 3 7.4 16.1 0.11 12.1 4.3 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4795) zf-RNPHF PF08080.12 EAX64165.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger DNA_pol_B_2 PF03175.13 EAX64169.1 - 2e-22 79.7 4.4 2.6e-22 79.3 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64169.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) T5orf172 PF10544.9 EAX64170.1 - 1.1e-07 32.3 0.3 2.3e-07 31.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX64170.1 - 0.085 13.5 0.4 0.24 12.1 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 BRX_N PF13713.6 EAX64171.1 - 0.00056 19.6 8.1 0.0044 16.7 1.8 3.2 2 0 0 2 2 2 1 Transcription factor BRX N-terminal domain DUF724 PF05266.14 EAX64171.1 - 0.082 12.7 41.3 0.19 11.5 14.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) XhlA PF10779.9 EAX64171.1 - 0.095 12.9 56.5 0.42 10.9 5.4 6.1 2 2 4 6 6 6 0 Haemolysin XhlA Nup54 PF13874.6 EAX64171.1 - 0.15 12.1 25.4 1.8 8.7 2.6 4.0 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 ATG16 PF08614.11 EAX64171.1 - 0.43 10.8 49.7 0.18 12.0 28.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MitMem_reg PF13012.6 EAX64171.1 - 0.51 10.8 8.3 0.19 12.1 1.2 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FUSC PF04632.12 EAX64171.1 - 1.8 7.0 15.0 1.7 7.1 1.6 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family RecR PF02132.15 EAX64171.1 - 5.2 6.7 9.6 9.8 5.8 0.1 5.1 6 0 0 6 6 6 0 RecR protein Jnk-SapK_ap_N PF09744.9 EAX64171.1 - 6.9 6.9 39.6 1.8 8.8 19.8 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2115 PF09888.9 EAX64171.1 - 7.6 7.0 19.3 0.49 10.9 2.1 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) TMP PF05017.14 EAX64172.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX64174.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX64174.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4107 PF13389.6 EAX64175.1 - 8.3e-67 224.4 2.1 9.9e-67 224.1 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64175.1 - 0.098 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta VirE PF05272.11 EAX64177.1 - 5.2e-06 26.3 0.0 9.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX64177.1 - 0.00018 21.9 1.9 0.00092 19.7 1.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64177.1 - 0.06 14.0 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain RNA_helicase PF00910.22 EAX64177.1 - 0.063 13.7 0.4 0.22 11.9 0.1 2.0 1 1 1 2 2 2 0 RNA helicase Cdc6_C PF09079.11 EAX64177.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PSP PF04046.16 EAX64178.1 - 0.052 13.4 0.6 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX64179.1 - 5.4e-151 500.8 16.2 6.7e-151 500.5 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX64179.1 - 0.14 12.0 1.3 0.47 10.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX64179.1 - 0.14 12.6 6.5 0.66 10.5 0.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX64180.1 - 2.7e-18 66.1 3.2 3.4e-18 65.8 3.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX64181.1 - 5.1e-10 38.8 1.6 9.7e-10 37.9 0.9 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX64182.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF3574 PF12098.8 EAX64184.1 - 0.28 11.0 1.4 0.32 10.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) DUF1493 PF07377.12 EAX64185.1 - 0.022 15.2 0.9 0.033 14.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64185.1 - 0.43 10.7 3.2 14 5.8 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX64186.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64187.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX64188.1 - 0.0044 17.0 0.2 0.0057 16.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX64189.1 - 4.7e-21 74.6 30.2 2.8e-20 72.1 7.7 3.6 4 1 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX64189.1 - 1.1 9.8 19.1 1.7 9.2 5.8 3.7 3 2 0 3 3 3 0 YmaF family TMP PF05017.14 EAX64190.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64191.1 - 0.07 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX64194.1 - 4e-07 30.5 0.3 6.8e-07 29.8 0.3 1.3 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX64194.1 - 0.1 13.3 0.3 0.24 12.1 0.3 1.6 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX64195.1 - 1.4e-31 108.6 0.1 3e-31 107.6 0.1 1.5 1 1 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX64196.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX64197.1 - 7.3e-07 28.9 2.5 7.3e-07 28.9 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX64197.1 - 3.9e-05 23.5 0.3 0.37 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64197.1 - 4.5e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64197.1 - 0.00032 20.7 4.2 0.00062 19.8 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64197.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64197.1 - 0.0015 18.3 0.7 0.0028 17.5 0.4 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64197.1 - 0.0061 16.2 2.9 0.014 15.0 0.5 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64197.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX64197.1 - 0.084 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX64197.1 - 0.091 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX64197.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64197.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64197.1 - 0.51 10.6 4.1 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX64197.1 - 0.68 10.6 11.7 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF5623 PF18536.1 EAX64198.1 - 0.082 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX64198.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PSP PF04046.16 EAX64199.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX64200.1 - 2.4e-09 36.6 1.8 3.1e-09 36.2 1.1 1.5 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64200.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_D5 PF03288.16 EAX64204.1 - 1.9e-05 25.0 3.0 0.00012 22.5 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64204.1 - 0.08 13.6 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain GPS2_interact PF15784.5 EAX64206.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX64207.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX64207.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PGP_phosphatase PF09419.10 EAX64209.1 - 0.0098 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase DUF2672 PF10878.8 EAX64209.1 - 0.58 10.1 5.7 0.12 12.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) DUF4107 PF13389.6 EAX64210.1 - 9.7e-67 224.2 1.9 1.3e-66 223.8 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64210.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF2897 PF11446.8 EAX64212.1 - 0.19 11.7 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) TMP PF05017.14 EAX64213.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64214.1 - 0.087 12.7 0.7 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 PSP TFCD_C PF12612.8 EAX64215.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal PadR PF03551.14 EAX64217.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MORN_2 PF07661.13 EAX64219.1 - 0.017 15.2 0.0 42 4.8 0.0 4.2 5 0 0 5 5 5 0 MORN repeat variant DUF2689 PF10894.8 EAX64219.1 - 0.079 12.7 4.3 2.9 7.7 0.1 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2689) BATS PF06968.13 EAX64219.1 - 0.087 13.0 0.0 16 5.7 0.0 3.0 2 2 1 3 3 3 0 Biotin and Thiamin Synthesis associated domain DUF3653 PF12375.8 EAX64219.1 - 0.11 12.6 3.8 43 4.3 0.0 4.1 3 1 1 4 4 4 0 Phage protein AAA_22 PF13401.6 EAX64220.1 - 2e-05 24.9 0.2 0.00015 22.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64220.1 - 2.9e-05 23.9 0.2 0.42 10.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64220.1 - 0.0001 22.3 2.8 0.00019 21.5 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64220.1 - 0.00041 20.2 0.1 0.00074 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX64220.1 - 0.00078 19.0 3.0 0.00078 19.0 3.0 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX64220.1 - 0.00095 19.0 0.5 0.0026 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64220.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX64220.1 - 0.047 13.2 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX64220.1 - 0.051 13.1 0.1 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64220.1 - 0.064 13.7 0.1 0.51 10.8 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64220.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64220.1 - 0.31 11.3 4.2 8.1 6.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX64222.1 - 1.1e-96 324.6 5.3 1.1e-96 324.6 5.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX64222.1 - 0.11 11.1 4.3 0.14 10.7 4.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2072 PF09845.9 EAX64222.1 - 4.5 7.6 6.7 8.1 6.7 5.7 1.9 2 1 0 2 2 2 0 Zn-ribbon containing protein GST_C PF00043.25 EAX64225.1 - 0.00025 21.2 0.2 1.8 8.8 0.0 3.0 1 1 2 3 3 3 2 Glutathione S-transferase, C-terminal domain ESAG1 PF03238.13 EAX64225.1 - 0.00031 20.3 3.7 0.42 10.0 0.1 3.1 1 1 2 3 3 3 2 ESAG protein DUF4795 PF16043.5 EAX64225.1 - 0.0012 18.5 2.1 0.84 9.2 0.4 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) Whi5 PF08528.11 EAX64225.1 - 0.008 15.8 0.4 49 3.7 0.0 4.0 3 3 0 3 3 3 0 Whi5 like Ribosomal_L12 PF00542.19 EAX64225.1 - 0.081 13.3 0.2 26 5.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain DUF5348 PF17295.2 EAX64225.1 - 0.084 12.8 3.8 37 4.3 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5348) PHA_gran_rgn PF09650.10 EAX64225.1 - 0.45 10.8 3.8 8.5 6.7 0.2 2.7 1 1 2 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) GP3_package PF16677.5 EAX64225.1 - 2.1 8.5 4.8 40 4.4 4.8 2.8 1 1 0 1 1 1 0 DNA-packaging protein gp3 Amidase02_C PF12123.8 EAX64227.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX64228.1 - 2.9e-24 85.1 0.8 6e-24 84.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX64228.1 - 0.0031 18.1 0.1 0.0094 16.6 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family DUF4108 PF13390.6 EAX64229.1 - 3.5e-72 241.0 11.8 3.9e-72 240.8 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) rve PF00665.26 EAX64230.1 - 4e-15 56.0 0.0 7.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EAX64230.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Hydrolase_6 PF13344.6 EAX64230.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pox_A32 PF04665.12 EAX64232.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX64234.1 - 1.2e-11 44.1 0.6 2.4e-11 43.2 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64234.1 - 0.012 15.0 0.5 0.016 14.5 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PTR PF12789.7 EAX64236.1 - 6.5e-51 170.2 30.4 3.6e-34 116.6 14.8 4.6 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX64236.1 - 0.021 14.5 1.1 0.037 13.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX64239.1 - 9.6e-08 31.8 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein GRDP-like PF07173.12 EAX64239.1 - 0.077 13.6 0.7 1.6 9.4 0.7 2.1 1 1 0 1 1 1 0 Glycine-rich domain-containing protein-like WRKY PF03106.15 EAX64240.1 - 0.015 15.5 3.2 0.035 14.3 0.8 2.6 1 1 1 2 2 2 0 WRKY DNA -binding domain FAS_N PF17828.1 EAX64241.1 - 0.0078 16.2 0.1 0.009 16.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta GGDEF PF00990.21 EAX64242.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX64242.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX64242.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX64244.1 - 3.4e-05 24.3 2.8 0.0002 21.8 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DNA_pol_B_2 PF03175.13 EAX64245.1 - 6.3e-11 41.8 7.8 9e-11 41.3 4.4 2.0 1 1 1 2 2 2 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX64245.1 - 0.093 12.3 0.8 0.18 11.3 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family Pox_A32 PF04665.12 EAX64246.1 - 2.8e-07 30.3 0.7 1.6e-06 27.8 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX64246.1 - 0.065 12.9 0.1 1.4 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4106 PF13388.6 EAX64247.1 - 2.9e-184 613.1 17.5 3.3e-184 613.0 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX64247.1 - 0.0054 17.0 0.1 0.37 11.1 0.1 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated Pox_D5 PF03288.16 EAX64248.1 - 5.9e-06 26.7 0.5 8.5e-06 26.2 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64248.1 - 0.039 14.6 0.1 0.052 14.2 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX64248.1 - 0.073 13.1 0.4 0.12 12.4 0.4 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX64249.1 - 2.1e-64 215.8 6.8 2.4e-64 215.6 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX64249.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX64250.1 - 0.17 11.8 3.0 0.22 11.4 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX64252.1 - 3.6e-68 228.8 1.5 4.7e-68 228.4 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX64254.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64255.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX64257.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64257.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX64257.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX64257.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64257.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX64257.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PapD_N PF00345.20 EAX64261.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain HEAT PF02985.22 EAX64262.1 - 0.17 12.3 0.0 4.2 7.9 0.0 3.1 4 0 0 4 4 4 0 HEAT repeat IstB_IS21 PF01695.17 EAX64264.1 - 9.8e-06 25.4 0.3 0.13 11.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64264.1 - 2.7e-05 24.5 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64264.1 - 0.00016 21.7 3.7 0.00031 20.8 3.7 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX64264.1 - 0.00018 21.1 2.1 0.00018 21.1 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX64264.1 - 0.00047 20.0 0.1 0.0008 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64264.1 - 0.0015 18.4 0.8 0.0036 17.1 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64264.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EAX64264.1 - 0.016 14.8 0.4 0.13 11.9 0.2 2.1 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX64264.1 - 0.043 13.3 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX64264.1 - 0.068 12.7 0.0 0.18 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64264.1 - 0.073 13.5 0.1 0.57 10.6 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64264.1 - 0.073 12.5 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX64264.1 - 0.29 11.1 1.7 2.6 8.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX64264.1 - 0.39 11.0 4.6 8.5 6.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX64265.1 - 7.7e-121 402.1 13.3 9.6e-121 401.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX64265.1 - 0.015 15.7 3.0 0.88 10.1 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX64265.1 - 0.1 12.1 0.7 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX64265.1 - 0.2 11.5 1.7 0.59 10.0 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX64267.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Mito_fiss_reg PF05308.11 EAX64268.1 - 0.13 12.3 0.4 0.13 12.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX64268.1 - 0.75 9.2 2.5 0.73 9.3 2.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMP PF05017.14 EAX64269.1 - 0.03 14.8 2.6 8.9 7.5 0.2 2.5 2 0 0 2 2 2 0 TMP repeat DUF4106 PF13388.6 EAX64271.1 - 2.8e-93 313.4 4.4 4.2e-93 312.9 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4106 PF13388.6 EAX64272.1 - 2.6e-45 155.4 64.4 1.5e-25 90.3 20.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) TMP PF05017.14 EAX64274.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX64275.1 - 0.067 13.7 0.3 0.12 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX64276.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64277.1 - 0.016 15.6 5.5 2.9 8.9 0.3 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX64279.1 - 4e-204 678.6 15.2 4.5e-204 678.4 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) TFIIA PF03153.13 EAX64279.1 - 0.96 9.4 11.2 1.2 9.0 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1043 PF06295.12 EAX64280.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CBM_15 PF03426.14 EAX64280.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF2939 PF11159.8 EAX64281.1 - 0.059 13.8 0.5 0.11 12.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64281.1 - 0.32 11.0 3.6 0.34 11.0 3.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX64283.1 - 0.037 14.5 0.8 0.074 13.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX64284.1 - 9.5e-06 25.6 0.6 9.5e-06 25.6 0.6 2.0 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX64284.1 - 0.13 11.8 0.3 3 7.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Amidase02_C PF12123.8 EAX64285.1 - 0.0031 17.2 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX64286.1 - 1.4e-11 43.9 0.3 3e-11 42.9 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64286.1 - 0.049 12.9 0.3 0.071 12.4 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3221 PF11518.8 EAX64288.1 - 0.027 14.8 1.2 0.051 13.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DNA_pol_B_2 PF03175.13 EAX64289.1 - 1.4e-10 40.7 3.0 1e-09 37.9 2.3 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64289.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Trypan_PARP PF05887.11 EAX64290.1 - 0.093 12.7 6.6 0.14 12.1 6.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX64290.1 - 2.6 8.5 5.1 3.6 8.0 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PSP PF04046.16 EAX64291.1 - 0.06 13.2 0.7 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64292.1 - 0.03 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX64293.1 - 1.2e-22 80.5 4.5 1.5e-22 80.1 4.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64293.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Amidase02_C PF12123.8 EAX64295.1 - 0.042 13.6 0.1 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX64296.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64297.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP FAS_N PF17828.1 EAX64300.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX64302.1 - 0.081 12.9 11.3 0.13 12.3 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HTH_32 PF13565.6 EAX64303.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PHM7_cyt PF14703.6 EAX64304.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PhaP_Bmeg PF09602.10 EAX64304.1 - 0.097 12.6 0.0 0.86 9.5 0.0 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FAS_N PF17828.1 EAX64305.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX64306.1 - 5.7e-07 29.2 3.7 1.4e-06 27.9 3.7 1.9 1 1 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64306.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64306.1 - 4.6e-05 23.2 0.2 0.33 10.7 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64306.1 - 0.00013 22.0 3.0 0.00032 20.7 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64306.1 - 0.00054 19.8 0.1 0.00096 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64306.1 - 0.0016 18.2 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64306.1 - 0.0019 17.9 0.4 0.013 15.1 0.1 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64306.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX64306.1 - 0.064 12.8 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX64306.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX64306.1 - 0.11 12.9 0.1 0.76 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAS_N PF17828.1 EAX64307.1 - 0.0095 15.9 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX64308.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Trypan_PARP PF05887.11 EAX64309.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX64310.1 - 5.3e-05 22.8 3.0 8.5e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64310.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX64310.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX64310.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 VirE PF05272.11 EAX64311.1 - 1.6e-05 24.7 0.1 2.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX64311.1 - 0.017 14.2 1.6 0.045 12.8 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) DUF2939 PF11159.8 EAX64312.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64312.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 BRO1 PF03097.18 EAX64314.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX64314.1 - 0.16 12.2 4.8 1.8 8.9 0.3 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX64314.1 - 0.18 12.4 1.6 2 9.0 1.7 2.2 1 1 0 1 1 1 0 YmaF family PTR PF12789.7 EAX64315.1 - 5.1e-58 193.0 40.9 7.9e-31 105.9 13.8 4.8 2 2 3 5 5 4 3 Phage tail repeat like HS1_rep PF02218.15 EAX64315.1 - 0.026 14.8 0.0 40 4.6 0.0 3.5 3 0 0 3 3 3 0 Repeat in HS1/Cortactin DUF4116 PF13475.6 EAX64315.1 - 0.028 14.2 0.9 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX64315.1 - 1.3 9.4 5.9 32 4.9 0.2 3.9 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain TMP PF05017.14 EAX64316.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX64317.1 - 3.4e-07 30.0 0.1 5.3e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein DUF846 PF05832.12 EAX64318.1 - 0.033 14.2 0.1 0.065 13.3 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Mito_fiss_reg PF05308.11 EAX64319.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX64319.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4378 PF14309.6 EAX64320.1 - 0.0025 18.2 0.1 0.0076 16.6 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4378) DUF2939 PF11159.8 EAX64321.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DDE_1 PF03184.19 EAX64322.1 - 7.2e-13 48.6 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidase02_C PF12123.8 EAX64323.1 - 0.0062 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX64324.1 - 1.9e-09 36.9 1.7 3.4e-09 36.1 1.1 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64324.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 DNA_pol_B PF00136.21 EAX64324.1 - 0.074 11.7 1.8 1.2 7.7 1.8 2.3 1 1 0 1 1 1 0 DNA polymerase family B TMP PF05017.14 EAX64325.1 - 0.09 13.4 5.4 11 7.3 0.2 3.3 3 1 1 4 4 4 0 TMP repeat PSP PF04046.16 EAX64326.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3574 PF12098.8 EAX64327.1 - 0.065 13.0 0.2 0.093 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) DNA_pol_B_2 PF03175.13 EAX64329.1 - 2.3e-09 36.7 1.9 3.4e-09 36.1 1.2 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64329.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 DNA_pol_B PF00136.21 EAX64329.1 - 0.1 11.3 2.1 1.6 7.3 1.9 2.3 1 1 0 1 1 1 0 DNA polymerase family B DUF2897 PF11446.8 EAX64330.1 - 1.9 8.4 3.7 3.6 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX64332.1 - 5.2e-64 214.5 6.8 5.7e-64 214.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX64332.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PTR PF12789.7 EAX64335.1 - 0.0074 16.3 0.4 0.0074 16.3 0.4 3.1 4 0 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX64335.1 - 0.061 12.9 1.6 0.14 11.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX64335.1 - 1.3 9.6 5.6 21 5.7 0.1 3.3 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX64335.1 - 2.1 8.7 16.2 3.2 8.2 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4116 PF13475.6 EAX64337.1 - 0.017 14.9 1.2 0.042 13.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAX64340.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP HD_2 PF12917.7 EAX64341.1 - 0.077 12.7 0.1 0.094 12.5 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme CTNNBL PF08216.11 EAX64342.1 - 0.1 12.8 0.1 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear FAS_N PF17828.1 EAX64344.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX64345.1 - 3e-54 180.9 30.8 1.6e-33 114.6 16.4 4.6 3 2 2 5 5 4 2 Phage tail repeat like ARA70 PF12489.8 EAX64346.1 - 0.099 12.8 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear coactivator W_rich_C PF07483.11 EAX64346.1 - 0.11 12.7 0.7 0.26 11.5 0.7 1.7 1 1 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain BRO1 PF03097.18 EAX64349.1 - 0.032 13.0 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX64349.1 - 5.5 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat IstB_IS21 PF01695.17 EAX64352.1 - 2e-05 24.4 0.4 0.24 11.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64352.1 - 2.1e-05 24.8 0.2 0.00021 21.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX64352.1 - 2.7e-05 23.7 1.6 2.7e-05 23.7 1.6 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX64352.1 - 0.00043 20.3 4.9 0.00073 19.6 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64352.1 - 0.00043 20.1 0.1 0.00084 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX64352.1 - 0.003 17.2 2.8 0.0098 15.6 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX64352.1 - 0.0034 17.2 1.8 0.0061 16.4 0.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64352.1 - 0.0073 16.7 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX64352.1 - 0.051 14.0 0.1 0.52 10.7 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX64352.1 - 0.073 12.6 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPK_catalytic PF04263.16 EAX64352.1 - 0.075 13.1 0.8 1.2 9.2 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX64352.1 - 0.088 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64352.1 - 0.59 10.4 4.9 8.4 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX64352.1 - 4.2 8.1 11.0 0.28 11.9 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 KIAA1430 PF13879.6 EAX64355.1 - 0.016 16.0 2.7 0.025 15.3 2.7 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX64356.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain T5orf172 PF10544.9 EAX64358.1 - 8.5e-07 29.5 0.2 1.8e-06 28.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX64358.1 - 0.093 13.4 0.3 0.23 12.1 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX64359.1 - 3.8e-33 113.7 1.0 4.7e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX64359.1 - 0.003 17.7 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX64359.1 - 0.23 11.9 6.0 2 8.9 1.3 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DNA_pol_B_2 PF03175.13 EAX64363.1 - 5.9e-09 35.3 1.4 8.7e-09 34.7 1.3 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX64363.1 - 0.09 12.8 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX64363.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 AAA_22 PF13401.6 EAX64365.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64365.1 - 7.5e-05 22.8 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64365.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64365.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64365.1 - 0.0021 17.8 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX64365.1 - 0.0078 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64365.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX64365.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX64365.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX64365.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX64365.1 - 0.24 11.7 4.5 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) RapH_N PF18801.1 EAX64366.1 - 1.1 9.4 5.5 7.5 6.7 0.3 2.4 1 1 1 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF4108 PF13390.6 EAX64367.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DDE_1 PF03184.19 EAX64368.1 - 2.7e-16 59.7 0.1 4.2e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX64368.1 - 5.3e-05 23.0 0.0 0.0028 17.4 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PadR PF03551.14 EAX64369.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RFX_DNA_binding PF02257.15 EAX64371.1 - 0.00011 22.8 0.2 0.00016 22.2 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX64371.1 - 0.00026 21.4 2.3 0.00044 20.7 2.3 1.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX64371.1 - 0.043 13.8 0.6 0.088 12.8 0.1 1.7 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4795 PF16043.5 EAX64372.1 - 0.0089 15.7 5.9 0.2 11.3 7.0 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX64372.1 - 0.03 14.9 1.7 0.092 13.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PTR PF12789.7 EAX64372.1 - 2.6 8.2 12.0 3.8 7.6 0.1 4.4 3 1 1 4 4 4 0 Phage tail repeat like zf-RING_4 PF14570.6 EAX64373.1 - 1.7e-16 59.7 15.6 3.4e-16 58.8 15.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EAX64373.1 - 1.4e-06 28.1 10.3 1.4e-06 28.1 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EAX64373.1 - 2.3e-05 24.1 2.2 0.0044 16.8 0.3 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_2 PF13639.6 EAX64373.1 - 0.0023 18.2 13.4 0.0023 18.2 13.4 2.0 2 0 0 2 2 2 1 Ring finger domain RRM_1 PF00076.22 EAX64373.1 - 0.003 17.4 0.1 0.015 15.2 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX64373.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Prok-RING_4 PF14447.6 EAX64373.1 - 0.029 14.2 7.4 0.029 14.2 7.4 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EAX64373.1 - 0.067 13.3 6.7 0.15 12.2 6.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 EAX64373.1 - 0.29 11.0 12.9 0.83 9.6 12.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EAX64373.1 - 3 7.8 12.5 0.57 10.1 8.6 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) NDUFB10 PF10249.9 EAX64375.1 - 0.08 13.5 0.4 14 6.2 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Gly-zipper_Omp PF13488.6 EAX64376.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX64376.1 - 0.077 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX64376.1 - 0.084 12.1 0.0 0.094 12.0 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX64376.1 - 0.23 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX64376.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DNA_pol_B_2 PF03175.13 EAX64377.1 - 3e-09 36.3 0.8 5.3e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX64377.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX64377.1 - 0.24 10.1 2.1 2.5 6.7 2.1 2.3 1 1 0 1 1 1 0 DNA polymerase family B T5orf172 PF10544.9 EAX64378.1 - 9.9e-07 29.3 0.2 2e-06 28.3 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX64378.1 - 0.089 13.5 0.3 0.24 12.1 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 PSP PF04046.16 EAX64379.1 - 0.063 13.2 0.7 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64380.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX64382.1 - 6.9e-06 26.6 0.0 7.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX64382.1 - 3.1e-05 24.4 0.0 3.4e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX64382.1 - 0.00057 20.1 0.0 0.00087 19.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX64382.1 - 0.019 15.5 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat DUF3839 PF12943.7 EAX64383.1 - 3.1e-60 203.7 3.6 3.4e-60 203.5 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX64385.1 - 2.1e-33 114.5 0.1 2.1e-33 114.5 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX64385.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX64385.1 - 0.13 10.8 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMP PF05017.14 EAX64387.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64388.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX64392.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX64395.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX64395.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PSP PF04046.16 EAX64396.1 - 0.11 12.3 1.2 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX64397.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX64397.1 - 1.3 9.6 4.0 8.1 7.1 1.6 2.7 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX64397.1 - 3.8 7.9 9.4 2.5 8.5 0.3 3.3 3 0 0 3 3 3 0 Phage tail fibre repeat Zn_peptidase PF04228.13 EAX64398.1 - 0.22 10.9 0.5 2.8 7.3 0.1 2.0 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase PapD_N PF00345.20 EAX64399.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX64399.1 - 0.074 13.0 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX64402.1 - 2.4e-77 259.7 8.0 3.1e-77 259.3 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX64403.1 - 0.041 13.9 8.7 0.064 13.2 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX64404.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX64405.1 - 1.3e-205 683.5 14.2 1.7e-205 683.1 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX64405.1 - 0.026 14.4 0.1 0.026 14.4 0.1 1.6 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX64405.1 - 0.4 10.6 14.7 0.53 10.2 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EAX64405.1 - 4.4 7.7 13.7 11 6.4 13.7 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Cytadhesin_P30 PF07271.11 EAX64407.1 - 0.69 9.4 9.8 0.86 9.1 9.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Nucleopor_Nup85 PF07575.13 EAX64409.1 - 0.014 14.0 0.0 0.023 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup85 Nucleoporin PSP PF04046.16 EAX64410.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TPR_MLP1_2 PF07926.12 EAX64411.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX64411.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX64411.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX64411.1 - 6.2 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family Amidase02_C PF12123.8 EAX64413.1 - 0.0062 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4795 PF16043.5 EAX64417.1 - 0.0073 15.9 3.8 0.041 13.5 3.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX64418.1 - 1.2e-37 128.2 0.1 1.2e-37 128.2 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX64418.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) ResIII PF04851.15 EAX64419.1 - 2e-05 24.7 0.2 2.4e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64419.1 - 0.00022 21.1 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64419.1 - 0.00036 20.8 0.0 0.00049 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64419.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64419.1 - 0.0056 17.0 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64419.1 - 0.03 13.8 0.0 0.032 13.7 0.0 1.3 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX64419.1 - 0.066 12.9 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX64419.1 - 0.067 12.8 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX64419.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX64419.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4342 PF14242.6 EAX64419.1 - 0.41 10.7 0.2 0.41 10.7 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) DUF2897 PF11446.8 EAX64421.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX64422.1 - 2.8e-05 24.2 1.0 4.9e-05 23.4 1.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64422.1 - 0.00032 20.5 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64422.1 - 0.00033 20.9 0.0 0.00051 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64422.1 - 0.0011 18.8 0.1 0.0018 18.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64422.1 - 0.016 15.5 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX64422.1 - 0.033 13.6 0.0 0.084 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX64422.1 - 0.038 13.7 0.2 0.064 12.9 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX64422.1 - 0.085 12.6 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX64422.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TMP PF05017.14 EAX64423.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX64424.1 - 0.015 15.7 0.5 0.028 14.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX64425.1 - 1.4e-09 37.4 6.3 1.7e-09 37.1 1.2 2.4 1 1 1 3 3 3 2 DNA polymerase type B, organellar and viral PhaP_Bmeg PF09602.10 EAX64425.1 - 0.063 13.2 0.1 0.85 9.5 0.1 2.2 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Isy1 PF06246.12 EAX64425.1 - 0.084 12.4 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 Isy1-like splicing family FAS_N PF17828.1 EAX64426.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX64427.1 - 2.6e-10 39.8 2.2 1.5e-09 37.2 2.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX64427.1 - 0.087 12.8 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX64427.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX64427.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) GvpK PF05121.12 EAX64428.1 - 0.39 10.8 4.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K DUF4107 PF13389.6 EAX64429.1 - 1.4e-65 220.4 1.6 1.8e-65 220.1 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_4 PF13637.6 EAX64431.1 - 2.8e-73 241.4 22.4 7.7e-12 45.5 0.1 8.6 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX64431.1 - 8.2e-71 231.6 14.7 1.4e-07 31.6 0.0 9.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_2 PF12796.7 EAX64431.1 - 1e-63 211.9 38.8 2.7e-18 66.4 4.4 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX64431.1 - 1.1e-56 182.1 15.0 4.1e-05 23.6 0.1 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 EAX64431.1 - 1.5e-38 130.4 16.6 3.9e-08 33.4 1.0 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) YcxB PF14317.6 EAX64431.1 - 0.00052 19.7 1.1 36 4.2 0.0 4.6 4 0 0 4 4 4 0 YcxB-like protein DUF5064 PF16703.5 EAX64431.1 - 0.00071 20.0 1.2 0.81 10.2 0.1 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF5064) Telomere_reg-2 PF10193.9 EAX64431.1 - 0.0029 18.0 1.7 2.4 8.6 0.2 2.6 2 1 0 2 2 2 2 Telomere length regulation protein TetR_C_17 PF17922.1 EAX64431.1 - 0.003 17.6 2.2 33 4.6 0.1 5.1 3 3 4 7 7 7 0 Tetracyclin repressor-like, C-terminal domain VirE_N PF08800.10 EAX64431.1 - 0.042 14.0 4.3 16 5.6 0.4 3.9 2 2 0 2 2 2 0 VirE N-terminal domain Diacid_rec PF05651.13 EAX64431.1 - 0.08 12.6 5.0 5 6.8 0.1 3.2 1 1 0 2 2 2 0 Putative sugar diacid recognition DUF4360 PF14273.6 EAX64431.1 - 0.17 11.7 2.5 17 5.2 0.2 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4360) MINDY_DUB PF04424.13 EAX64431.1 - 0.59 10.2 5.2 27 4.8 0.1 4.0 4 1 0 4 4 4 0 MINDY deubiquitinase HTH_45 PF14947.6 EAX64431.1 - 0.89 9.6 6.0 15 5.7 0.4 3.1 2 1 0 2 2 2 0 Winged helix-turn-helix DUF348 PF03990.14 EAX64431.1 - 0.93 9.3 4.0 1.3e+02 2.4 0.1 4.6 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain Ubiquitin_3 PF14836.6 EAX64431.1 - 2.3 8.3 8.6 1.1e+02 2.9 0.0 5.4 4 2 0 5 5 5 0 Ubiquitin-like domain PHR PF08005.12 EAX64431.1 - 5.7 7.6 10.5 17 6.0 1.2 3.1 1 1 3 4 4 4 0 PHR domain DUF2149 PF09919.9 EAX64431.1 - 7.2 6.9 11.5 2.3e+02 2.1 0.0 5.8 1 1 8 9 9 9 0 Uncharacterized conserved protein (DUF2149) Pox_A32 PF04665.12 EAX64432.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64432.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64432.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64432.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64432.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64432.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64432.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64432.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX64432.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64432.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64432.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64432.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX64433.1 - 0.14 12.0 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) FAS_N PF17828.1 EAX64434.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX64435.1 - 1.7e-154 512.3 12.9 2e-154 512.0 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX64435.1 - 0.052 13.9 0.1 12 6.3 0.0 2.9 2 0 0 2 2 2 0 Tup N-terminal KELK PF15796.5 EAX64435.1 - 0.075 13.5 1.1 5 7.6 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX64435.1 - 0.5 10.9 3.7 0.62 10.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2897 PF11446.8 EAX64436.1 - 0.64 10.0 4.2 1.4 8.9 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX64437.1 - 3.2e-63 211.9 5.9 3.6e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX64438.1 - 4.9e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64438.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX64438.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MULE PF10551.9 EAX64440.1 - 1.3e-11 44.8 0.1 2.4e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX64440.1 - 0.068 13.3 3.6 0.13 12.4 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain Amidase02_C PF12123.8 EAX64441.1 - 0.0073 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1493 PF07377.12 EAX64442.1 - 0.092 13.2 0.4 0.19 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64442.1 - 0.76 9.9 3.6 12 6.0 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DNA_pol_B_2 PF03175.13 EAX64443.1 - 2e-09 36.9 1.9 2.8e-09 36.4 1.1 1.5 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64443.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 AAA_22 PF13401.6 EAX64445.1 - 1.5e-05 25.3 0.2 0.00012 22.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64445.1 - 1.9e-05 24.4 0.2 0.31 10.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64445.1 - 0.00011 22.3 3.2 0.00018 21.6 3.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64445.1 - 0.00035 20.4 0.1 0.00055 19.8 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64445.1 - 0.0011 18.9 0.8 0.0028 17.5 0.8 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX64445.1 - 0.0015 18.0 1.7 0.0015 18.0 1.7 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX64445.1 - 0.0092 16.3 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX64445.1 - 0.034 13.7 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX64445.1 - 0.045 13.2 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX64445.1 - 0.055 13.9 0.1 0.44 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64445.1 - 0.06 12.8 0.1 0.099 12.1 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX64445.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX64445.1 - 0.31 11.3 4.7 7 7.0 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX64446.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX64447.1 - 6.6e-07 29.0 1.8 6.6e-07 29.0 1.8 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX64447.1 - 3.1e-05 23.8 0.4 0.31 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64447.1 - 4.2e-05 23.8 0.2 0.00031 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64447.1 - 0.00043 20.3 4.7 0.00071 19.6 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64447.1 - 0.00073 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64447.1 - 0.0028 17.5 1.4 0.0063 16.3 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64447.1 - 0.0058 16.3 2.9 0.015 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64447.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX64447.1 - 0.081 13.0 0.7 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX64447.1 - 0.087 12.4 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64447.1 - 0.1 13.0 0.1 0.91 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64447.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF573 PF04504.14 EAX64447.1 - 0.41 11.3 11.0 0.33 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX64447.1 - 0.83 9.9 4.9 9.8 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX64448.1 - 4e-18 65.9 23.5 1.6e-16 60.6 23.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Nucleo_P87 PF07267.11 EAX64448.1 - 0.26 10.1 5.7 0.25 10.2 5.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1493 PF07377.12 EAX64449.1 - 0.053 14.0 0.2 0.087 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX64451.1 - 1.6e-08 33.8 1.4 2.9e-08 33.0 0.9 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64451.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 TMP PF05017.14 EAX64455.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX64456.1 - 0.013 15.5 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta TPR_MLP1_2 PF07926.12 EAX64457.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX64457.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX64457.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX64457.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family PSP PF04046.16 EAX64458.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64459.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX64460.1 - 0.013 15.9 0.6 0.024 15.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX64461.1 - 0.059 13.8 0.3 0.11 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64461.1 - 0.66 10.1 3.3 13 5.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein KilA-N PF04383.13 EAX64462.1 - 1.3e-41 141.0 0.1 2e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain LZ3wCH PF18517.1 EAX64462.1 - 0.1 12.7 0.9 0.18 11.9 0.3 1.8 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DUF3839 PF12943.7 EAX64465.1 - 2.6e-156 518.2 14.4 3.3e-156 517.9 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX64465.1 - 0.02 15.4 2.0 0.066 13.7 0.4 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX64465.1 - 0.17 11.7 1.5 0.47 10.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX64465.1 - 0.96 9.9 8.2 2.1 8.8 1.0 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX64466.1 - 3e-96 321.6 8.2 3.6e-96 321.3 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX64466.1 - 0.094 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Z1 domain TMP PF05017.14 EAX64470.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX64472.1 - 0.067 13.8 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64473.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PcfK PF14058.6 EAX64474.1 - 0.1 12.9 8.6 0.15 12.3 8.6 1.4 1 1 0 1 1 1 0 PcfK-like protein Pox_A32 PF04665.12 EAX64475.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein YABBY PF04690.13 EAX64476.1 - 0.045 14.3 0.9 0.08 13.5 0.4 1.6 2 0 0 2 2 2 0 YABBY protein MORN_2 PF07661.13 EAX64477.1 - 0.032 14.4 0.0 24 5.6 0.0 3.3 3 0 0 3 3 3 0 MORN repeat variant DUF2689 PF10894.8 EAX64477.1 - 0.074 12.8 0.8 13 5.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2689) Autophagy_N PF03986.13 EAX64477.1 - 0.16 11.9 0.3 3.4 7.6 0.0 2.3 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain RSS_P20 PF11757.8 EAX64478.1 - 0.1 13.1 2.8 2.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF3027 PF11228.8 EAX64479.1 - 0.15 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) TMP PF05017.14 EAX64481.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX64483.1 - 0.06 13.8 0.5 0.15 12.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) YvrJ PF12841.7 EAX64486.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family PTR PF12789.7 EAX64487.1 - 2.7e-09 36.9 1.7 2.7e-09 36.9 1.7 4.7 5 2 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX64487.1 - 0.003 17.2 13.4 0.074 12.6 1.6 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Cas_Csm6 PF09659.10 EAX64487.1 - 0.0044 15.9 0.6 0.0063 15.3 0.6 1.4 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) ATR13 PF16829.5 EAX64487.1 - 1.5 9.3 5.1 2.5 8.5 2.3 2.4 2 1 1 3 3 3 0 Avirulence protein ATR13, RxLR effector T5orf172 PF10544.9 EAX64488.1 - 4.2e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX64489.1 - 0.02 15.3 0.8 0.039 14.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX64492.1 - 0.0033 17.1 0.1 0.0097 15.6 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase HD_2 PF12917.7 EAX64493.1 - 0.13 12.0 0.2 0.15 11.8 0.2 1.0 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme TMP PF05017.14 EAX64496.1 - 0.042 14.4 5.6 9.3 7.4 0.2 3.4 3 1 1 4 4 4 0 TMP repeat TMP PF05017.14 EAX64498.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64499.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX64501.1 - 0.025 14.6 8.2 0.031 14.3 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX64501.1 - 7.8 6.9 6.1 9.6 6.6 6.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 EAX64503.1 - 0.04 13.9 8.4 0.054 13.5 8.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX64504.1 - 3.6e-07 29.9 0.0 5.2e-07 29.4 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX64505.1 - 5.7e-17 61.7 2.2 6.9e-17 61.5 2.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX64506.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64506.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64506.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64506.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) BRO1 PF03097.18 EAX64507.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX64507.1 - 5.5 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX64508.1 - 1.7e-22 79.9 4.2 2.2e-22 79.6 4.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3781 PF12636.7 EAX64509.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX64510.1 - 5.3e-07 29.3 0.2 6.4e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX64511.1 - 3.5e-22 78.9 5.1 4.6e-22 78.5 5.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TMP PF05017.14 EAX64512.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64513.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP PTR PF12789.7 EAX64514.1 - 2e-05 24.6 0.6 2e-05 24.6 0.6 3.0 3 1 0 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX64514.1 - 0.0089 15.9 3.6 0.012 15.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) MeaB PF03308.16 EAX64514.1 - 0.054 12.5 0.5 0.087 11.8 0.5 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX64514.1 - 0.055 13.9 1.5 0.14 12.6 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX64514.1 - 0.12 12.0 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX64514.1 - 0.32 10.6 12.4 0.43 10.2 6.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PGBA_C PF15437.6 EAX64515.1 - 2.4 8.6 8.9 0.96 9.9 1.1 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal LMBR1 PF04791.16 EAX64515.1 - 3.1 6.6 11.5 4 6.2 11.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pox_D5 PF03288.16 EAX64517.1 - 4.6e-06 27.0 2.5 2.5e-05 24.7 2.5 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64517.1 - 0.022 15.4 0.1 0.041 14.5 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX64517.1 - 0.061 13.3 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2960 PF11173.8 EAX64518.1 - 0.014 15.9 0.3 0.037 14.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) KilA-N PF04383.13 EAX64519.1 - 1.1e-44 150.9 0.2 1.1e-44 150.9 0.2 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX64519.1 - 0.023 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF4108 PF13390.6 EAX64521.1 - 5.6e-64 214.4 5.6 6.3e-64 214.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64522.1 - 0.74 9.7 4.2 1.6 8.7 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GGDEF PF00990.21 EAX64523.1 - 0.036 13.8 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain FAS_N PF17828.1 EAX64525.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KIAA1430 PF13879.6 EAX64526.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX64527.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain MULE PF10551.9 EAX64528.1 - 1.1e-11 45.0 0.1 2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX64528.1 - 0.06 13.5 3.6 0.11 12.6 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX64528.1 - 0.078 13.7 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain IstB_IS21 PF01695.17 EAX64529.1 - 2.4e-05 24.1 0.3 0.29 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64529.1 - 2.8e-05 24.4 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX64529.1 - 3.4e-05 23.4 2.1 3.4e-05 23.4 2.1 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX64529.1 - 0.00031 20.8 4.4 0.00048 20.2 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64529.1 - 0.00053 19.8 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64529.1 - 0.0016 18.3 1.1 0.0032 17.3 0.4 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64529.1 - 0.0027 17.4 2.6 0.0096 15.6 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64529.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX64529.1 - 0.061 13.4 0.7 0.99 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Elong_Iki1 PF10483.9 EAX64529.1 - 0.062 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX64529.1 - 0.066 12.8 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64529.1 - 0.073 13.5 0.1 0.7 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64529.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64529.1 - 0.47 10.7 4.7 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX64529.1 - 4.9 7.9 11.1 0.28 11.9 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 TMP PF05017.14 EAX64531.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64532.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Mitofilin PF09731.9 EAX64533.1 - 0.012 14.4 1.4 0.015 14.2 1.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Noggin PF05806.12 EAX64533.1 - 0.074 13.0 0.6 0.092 12.7 0.6 1.1 1 0 0 1 1 1 0 Noggin DNA_pol_B_2 PF03175.13 EAX64534.1 - 3.1e-24 85.7 6.7 3.8e-24 85.4 6.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64534.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX64535.1 - 2.2e-121 403.9 13.3 2.7e-121 403.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX64535.1 - 0.041 14.3 3.1 1.8 9.0 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX64535.1 - 0.11 12.1 0.7 0.31 10.5 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX64535.1 - 0.24 11.2 1.9 0.65 9.8 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX64535.1 - 0.35 11.4 2.0 0.31 11.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX64536.1 - 3.8e-08 32.6 1.3 5.8e-08 32.0 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64536.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX64536.1 - 0.1 12.6 0.0 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX64537.1 - 1.3e-35 121.7 1.4 1.6e-35 121.3 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX64537.1 - 0.0045 17.6 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX64537.1 - 0.86 9.6 4.2 2.7 8.0 0.4 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF3417 PF11897.8 EAX64538.1 - 0.11 13.0 0.4 0.13 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX64538.1 - 0.6 10.0 2.6 1.2 9.1 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX64539.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX64541.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX64541.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX64542.1 - 4.2e-09 35.8 0.8 6e-09 35.3 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX64542.1 - 0.084 12.9 0.0 0.66 10.0 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX64542.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF1493 PF07377.12 EAX64543.1 - 0.026 15.0 0.4 0.05 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64543.1 - 0.42 10.7 3.9 7.8 6.6 0.2 2.7 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX64545.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein PTR PF12789.7 EAX64546.1 - 8.2e-54 179.5 36.7 5.9e-35 119.1 16.2 4.7 2 2 3 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX64546.1 - 0.039 13.7 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX64547.1 - 0.069 13.7 6.2 6.1 8.0 0.5 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX64547.1 - 8.9 6.3 9.0 9.5 6.2 9.0 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX64548.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX64549.1 - 0.0068 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX64550.1 - 3.6e-18 65.4 0.1 4.6e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain 2_5_RNA_ligase2 PF13563.6 EAX64551.1 - 0.038 13.9 0.0 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Col_cuticle_N PF01484.17 EAX64551.1 - 0.15 12.2 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF1493 PF07377.12 EAX64552.1 - 0.035 14.6 0.6 0.075 13.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX64553.1 - 0.019 15.4 0.4 0.043 14.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64553.1 - 0.6 10.2 3.8 7.4 6.7 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX64554.1 - 2.8e-82 275.8 7.9 3.3e-82 275.6 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX64554.1 - 0.078 13.9 0.8 2.9 8.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Glu-tRNAGln PF02686.15 EAX64554.1 - 0.15 12.4 1.0 0.35 11.2 1.0 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4795 PF16043.5 EAX64556.1 - 0.016 14.8 1.7 0.042 13.5 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX64556.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.4 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX64556.1 - 0.084 13.1 12.8 3.3 8.1 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX64556.1 - 0.78 10.3 5.4 17 6.1 0.1 3.2 3 1 0 3 3 3 0 YmaF family DUF4107 PF13389.6 EAX64557.1 - 1.6e-54 184.4 0.7 2.1e-54 184.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64557.1 - 0.079 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX64559.1 - 1.6e-72 243.0 4.1 2.1e-72 242.6 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF257 PF03192.13 EAX64560.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX64560.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p KilA-N PF04383.13 EAX64561.1 - 6.8e-35 119.3 0.2 1e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX64561.1 - 0.002 18.3 0.1 0.0048 17.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX64561.1 - 0.0041 17.5 4.3 0.09 13.2 0.8 2.4 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 T5orf172 PF10544.9 EAX64562.1 - 3.5e-07 30.7 0.1 5.9e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 T5orf172 domain DUF4795 PF16043.5 EAX64563.1 - 0.0061 16.2 6.0 0.033 13.8 6.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX64564.1 - 6.6e-18 64.8 3.5 7.8e-18 64.6 3.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64564.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Mito_fiss_reg PF05308.11 EAX64566.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX64566.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX64567.1 - 0.081 13.4 0.5 0.18 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX64568.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX64569.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DAO_C PF16901.5 EAX64570.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF3839 PF12943.7 EAX64571.1 - 8.7e-111 369.2 8.1 1e-110 369.0 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX64571.1 - 0.045 13.2 0.8 0.062 12.8 0.7 1.3 1 1 0 1 1 1 0 Z1 domain PTR PF12789.7 EAX64575.1 - 2.2e-05 24.4 0.6 2.2e-05 24.4 0.6 3.2 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX64575.1 - 0.013 14.8 0.4 0.021 14.1 0.4 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF445 PF04286.12 EAX64575.1 - 0.026 14.3 0.6 0.035 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX64575.1 - 0.045 13.3 4.3 0.11 12.1 4.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) MeaB PF03308.16 EAX64575.1 - 0.06 12.3 0.4 0.097 11.6 0.4 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX64575.1 - 0.071 13.6 0.3 0.31 11.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAX64576.1 - 5.4e-148 491.0 13.6 6.6e-148 490.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX64576.1 - 0.036 14.6 3.0 0.18 12.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX64576.1 - 0.31 11.5 3.8 9.3 6.8 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2486 PF10667.9 EAX64578.1 - 0.18 12.0 29.8 0.12 12.6 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Amidase02_C PF12123.8 EAX64580.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX64581.1 - 0.13 12.9 7.2 6.3 7.9 0.8 3.2 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX64581.1 - 6.6 6.7 8.4 7.2 6.6 8.4 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX64582.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP YmaF PF12788.7 EAX64583.1 - 0.06 13.9 1.5 0.36 11.4 1.5 1.9 1 1 0 1 1 1 0 YmaF family Trypan_PARP PF05887.11 EAX64584.1 - 0.4 10.7 11.6 0.6 10.1 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX64584.1 - 5.6 7.4 6.8 8.4 6.8 6.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Nab1 PF04902.12 EAX64585.1 - 0.029 14.8 0.8 0.031 14.7 0.8 1.0 1 0 0 1 1 1 0 Conserved region in Nab1 DUF4106 PF13388.6 EAX64589.1 - 1.4e-96 324.3 4.6 2.1e-96 323.7 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX64590.1 - 0.0034 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX64590.1 - 0.18 11.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX64591.1 - 0.00023 20.7 2.8 0.0004 19.9 2.8 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64591.1 - 0.0037 17.3 0.7 0.0095 16.0 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX64591.1 - 0.0075 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX64591.1 - 0.042 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX64591.1 - 0.074 13.3 1.5 0.14 12.4 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) TMP PF05017.14 EAX64592.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64593.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX64595.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX64595.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX64597.1 - 2.5e-22 78.9 0.3 4.4e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX64597.1 - 0.012 15.6 1.3 0.077 13.0 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX64597.1 - 0.24 10.8 0.7 0.61 9.5 0.7 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain NTS PF15447.6 EAX64597.1 - 1.3 9.6 4.2 7.1 7.2 1.6 2.5 1 1 1 2 2 2 0 N-terminal segments of PfEMP1 TIG PF01833.24 EAX64598.1 - 3.9e-06 26.8 0.1 8.7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_M8 PF01457.16 EAX64598.1 - 3.8e-05 22.6 1.3 4.8e-05 22.2 1.3 1.1 1 0 0 1 1 1 1 Leishmanolysin PSP PF04046.16 EAX64603.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX64605.1 - 1.1e-07 31.6 0.1 1.3e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein TMP PF05017.14 EAX64608.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64609.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX64610.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX64610.1 - 0.035 14.1 0.4 0.047 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX64610.1 - 0.062 13.3 0.2 0.079 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tctex-1 PF03645.13 EAX64611.1 - 0.058 13.6 0.6 0.072 13.3 0.6 1.2 1 0 0 1 1 1 0 Tctex-1 family HTH_32 PF13565.6 EAX64611.1 - 0.32 11.6 4.6 0.45 11.2 4.6 1.2 1 0 0 1 1 1 0 Homeodomain-like domain TSP_NTD PF17804.1 EAX64611.1 - 0.52 10.5 5.8 0.64 10.3 5.8 1.1 1 0 0 1 1 1 0 Tail specific protease N-terminal domain CENP-H PF05837.12 EAX64611.1 - 5.5 7.4 12.1 21 5.6 12.1 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FAS_N PF17828.1 EAX64612.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX64613.1 - 2.2e-87 292.6 6.5 2.5e-87 292.4 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_D5 PF03288.16 EAX64614.1 - 2.3e-05 24.8 2.1 0.00011 22.6 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64614.1 - 0.064 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Pox_A32 PF04665.12 EAX64617.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64617.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64617.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64617.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX64618.1 - 0.034 14.6 0.7 0.069 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX64619.1 - 4.4e-05 23.0 3.9 7.8e-05 22.2 3.9 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64619.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX64619.1 - 0.01 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX64619.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX64619.1 - 0.068 13.5 2.1 0.15 12.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF1493 PF07377.12 EAX64620.1 - 0.022 15.2 1.6 0.029 14.8 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) Antimicrobial_8 PF08103.11 EAX64621.1 - 0.54 10.5 2.6 0.91 9.8 0.6 2.5 2 0 0 2 2 2 0 Uperin family MAP7 PF05672.11 EAX64622.1 - 0.36 10.5 57.8 0.1 12.3 52.6 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family PA26 PF04636.13 EAX64622.1 - 9.7 5.0 11.1 14 4.4 11.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4108 PF13390.6 EAX64623.1 - 2.1e-53 180.1 7.8 2.3e-53 180.0 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64624.1 - 0.51 10.3 2.6 0.95 9.4 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX64626.1 - 8.6e-05 22.9 3.0 0.00049 20.5 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX64626.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF1493 PF07377.12 EAX64627.1 - 0.022 15.2 0.5 0.044 14.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64627.1 - 0.36 10.9 4.0 5.6 7.1 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX64630.1 - 4.3e-107 357.1 8.3 4.9e-107 356.9 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-RNPHF PF08080.12 EAX64632.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger Transposase_mut PF00872.18 EAX64634.1 - 0.0025 16.7 0.8 0.0034 16.3 0.4 1.5 1 1 0 1 1 1 1 Transposase, Mutator family DUF2178 PF09946.9 EAX64634.1 - 0.12 12.5 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Pox_A32 PF04665.12 EAX64635.1 - 0.00012 21.6 2.6 0.00012 21.6 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64635.1 - 0.0047 16.9 0.7 0.012 15.7 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX64635.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Amidase02_C PF12123.8 EAX64636.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX64637.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX64637.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MULE PF10551.9 EAX64638.1 - 1.2e-11 44.9 0.1 2e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX64638.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 PWI domain AAA_22 PF13401.6 EAX64639.1 - 6.5e-05 23.2 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64639.1 - 0.00012 22.2 3.1 0.00021 21.3 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64639.1 - 0.00046 20.0 0.0 0.00069 19.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64639.1 - 0.0013 18.6 1.2 0.0044 16.9 1.3 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64639.1 - 0.0056 16.4 0.2 1.1 9.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX64639.1 - 0.0083 16.5 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64639.1 - 0.046 13.2 0.1 0.098 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX64639.1 - 0.11 13.0 0.1 0.41 11.1 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX64639.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX64640.1 - 3.3e-07 30.0 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64640.1 - 0.0045 16.7 0.1 0.006 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX64640.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX64640.1 - 0.063 13.0 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX64640.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX64640.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX64640.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) FAS_N PF17828.1 EAX64642.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX64643.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64644.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX64645.1 - 5.7e-07 29.2 0.0 6.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF4106 PF13388.6 EAX64647.1 - 3.2e-122 408.8 14.1 5.6e-122 408.0 14.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) T5orf172 PF10544.9 EAX64648.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MULE PF10551.9 EAX64650.1 - 0.014 15.8 1.8 0.082 13.3 0.1 2.8 2 1 0 3 3 3 0 MULE transposase domain DUF2960 PF11173.8 EAX64650.1 - 0.027 14.9 0.4 0.065 13.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Pox_A32 PF04665.12 EAX64652.1 - 5.7e-05 22.7 0.3 6.6e-05 22.5 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF2960 PF11173.8 EAX64653.1 - 0.036 14.5 0.4 0.085 13.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) BLOC1_2 PF10046.9 EAX64653.1 - 0.039 14.2 1.1 4.5 7.6 0.1 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YvrJ PF12841.7 EAX64654.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family MULE PF10551.9 EAX64656.1 - 4.8e-05 23.7 0.0 9.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAS_N PF17828.1 EAX64657.1 - 0.0036 17.3 0.3 0.0041 17.1 0.3 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Gly_rich PF12810.7 EAX64658.1 - 9.5e-50 169.8 33.4 1.1e-49 169.5 33.4 1.1 1 0 0 1 1 1 1 Glycine rich protein PapD_N PF00345.20 EAX64661.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX64662.1 - 5.2e-55 185.3 6.6 5.8e-55 185.2 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Apolipoprotein PF01442.18 EAX64663.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain JMY PF15871.5 EAX64664.1 - 0.017 14.5 0.4 0.023 14.0 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4108 PF13390.6 EAX64666.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HD_2 PF12917.7 EAX64668.1 - 0.083 12.6 0.1 0.1 12.3 0.1 1.0 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme FAS_N PF17828.1 EAX64670.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX64671.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX64671.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX64671.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX64671.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX64672.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64673.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX64674.1 - 0.043 14.3 1.0 0.064 13.7 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64674.1 - 0.41 10.7 3.2 12 6.1 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4106 PF13388.6 EAX64675.1 - 7.2e-93 312.1 4.2 8.4e-93 311.9 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) GGDEF PF00990.21 EAX64676.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX64676.1 - 9.3 6.2 6.6 20 5.2 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX64677.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX64678.1 - 4.3e-41 139.3 0.1 4.3e-41 139.3 0.1 1.9 3 0 0 3 3 3 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX64678.1 - 0.022 14.0 0.2 0.087 12.0 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX64678.1 - 0.22 10.0 0.1 0.32 9.5 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Hormone_1 PF00103.20 EAX64678.1 - 0.83 9.4 6.1 5.1 6.8 4.8 2.0 1 1 1 2 2 2 0 Somatotropin hormone family PapD_N PF00345.20 EAX64680.1 - 0.066 13.1 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PSP PF04046.16 EAX64681.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GGDEF PF00990.21 EAX64682.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX64682.1 - 8.2 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX64683.1 - 2.8e-05 24.2 1.5 5.2e-05 23.3 1.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64683.1 - 0.00029 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64683.1 - 0.00036 20.8 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64683.1 - 0.0011 18.8 0.2 0.0022 17.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64683.1 - 0.0061 16.9 0.0 0.0081 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64683.1 - 0.033 13.6 0.1 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX64683.1 - 0.076 12.7 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX64683.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX64683.1 - 0.23 11.2 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX64683.1 - 0.62 10.5 3.7 0.33 11.4 0.7 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PapD_N PF00345.20 EAX64684.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX64684.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Gly-zipper_Omp PF13488.6 EAX64687.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX64687.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX64687.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2939 PF11159.8 EAX64688.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64688.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4106 PF13388.6 EAX64689.1 - 5.6e-59 200.4 0.7 6.2e-59 200.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) AAA_22 PF13401.6 EAX64691.1 - 5.4e-05 23.5 0.1 0.00032 21.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64691.1 - 6.9e-05 22.9 2.8 0.00013 22.0 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64691.1 - 0.00035 20.4 0.0 0.00048 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64691.1 - 0.00096 19.0 1.1 0.0031 17.3 1.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64691.1 - 0.0057 16.4 0.3 0.19 11.5 0.0 2.5 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX64691.1 - 0.0071 16.7 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64691.1 - 0.044 13.2 0.1 0.069 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX64691.1 - 0.064 13.0 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX64691.1 - 0.11 13.0 0.0 0.37 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX64691.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX64691.1 - 0.2 11.9 4.5 5.2 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX64691.1 - 0.79 10.2 4.0 0.39 11.2 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX64693.1 - 3.2e-63 211.9 5.9 3.5e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64694.1 - 1.6 8.7 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1493 PF07377.12 EAX64695.1 - 0.034 14.6 0.6 0.064 13.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX64696.1 - 2.2e-71 238.4 12.2 2.5e-71 238.2 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX64698.1 - 0.031 14.8 0.7 0.066 13.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2960 PF11173.8 EAX64700.1 - 0.021 15.3 0.4 0.049 14.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX64700.1 - 0.038 14.0 1.9 0.21 11.6 0.5 2.5 2 1 1 3 3 3 0 YpjP-like protein TMP PF05017.14 EAX64702.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64703.1 - 0.053 13.4 0.8 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX64705.1 - 2.6e-82 277.3 4.4 3e-82 277.1 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4106 PF13388.6 EAX64706.1 - 2.4e-50 172.0 29.9 1.6e-49 169.3 29.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX64707.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX64707.1 - 0.17 11.7 0.1 2 8.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1731) Mito_fiss_reg PF05308.11 EAX64709.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX64709.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PSP PF04046.16 EAX64710.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX64711.1 - 1.1e-57 194.0 4.1 1.2e-57 193.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64712.1 - 0.27 11.1 3.6 0.55 10.2 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX64712.1 - 0.28 11.6 2.4 0.33 11.3 2.4 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4108 PF13390.6 EAX64713.1 - 2.1e-63 212.5 5.9 2.3e-63 212.4 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX64714.1 - 1.4e-05 25.5 0.4 2.1e-05 24.9 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64714.1 - 0.015 15.9 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX64714.1 - 0.038 14.0 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2400 PF09674.10 EAX64717.1 - 0.028 14.4 0.7 0.036 14.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF846 PF05832.12 EAX64720.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) TMP PF05017.14 EAX64721.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64722.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX64723.1 - 3.8e-05 23.3 4.3 6.7e-05 22.5 4.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX64723.1 - 0.0035 17.4 0.8 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX64723.1 - 0.011 15.3 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX64723.1 - 0.057 13.7 1.5 0.15 12.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) WRKY PF03106.15 EAX64724.1 - 0.028 14.7 0.9 0.028 14.7 0.9 2.7 2 1 1 3 3 3 0 WRKY DNA -binding domain VIGSSK PF14773.6 EAX64724.1 - 0.4 10.8 2.0 16 5.7 0.2 2.4 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal AAA_22 PF13401.6 EAX64725.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64725.1 - 7.8e-05 22.7 3.0 0.00014 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX64725.1 - 0.00013 21.8 0.4 0.41 10.3 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX64725.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64725.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64725.1 - 0.0088 16.4 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64725.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX64725.1 - 0.067 13.6 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX64725.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX64725.1 - 0.16 12.2 4.2 4.7 7.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX64726.1 - 5.3e-155 513.9 13.1 6.6e-155 513.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX64726.1 - 0.02 14.9 0.1 5.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NTP_transf_6 PF06042.11 EAX64726.1 - 0.066 13.1 1.4 0.2 11.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX64726.1 - 0.12 12.7 1.9 13 6.1 0.0 3.4 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX64726.1 - 0.69 10.4 5.3 1.1 9.8 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX64727.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64728.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX64730.1 - 3.1e-17 62.4 1.5 3.1e-17 62.4 1.5 3.0 4 0 0 4 4 4 1 Phage tail repeat like Pox_A32 PF04665.12 EAX64731.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64731.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64731.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64731.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DNA_pol_B_2 PF03175.13 EAX64732.1 - 8.6e-22 77.6 6.2 1e-20 74.1 6.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64732.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF5446 PF17522.2 EAX64734.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF2897 PF11446.8 EAX64735.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1493 PF07377.12 EAX64736.1 - 0.071 13.6 0.9 0.15 12.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) RFX_DNA_binding PF02257.15 EAX64737.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX64737.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX64737.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DNA_pol_B_2 PF03175.13 EAX64739.1 - 6.6e-23 81.3 4.4 8.4e-23 81.0 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64739.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) T5orf172 PF10544.9 EAX64741.1 - 2.3e-06 28.1 0.1 4.9e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX64741.1 - 0.025 14.4 1.7 0.073 12.9 0.7 2.2 2 1 0 2 2 2 0 KilA-N domain PTR PF12789.7 EAX64742.1 - 9.4e-05 22.4 1.1 9.4e-05 22.4 1.1 2.8 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX64742.1 - 0.37 11.4 5.3 2.5 8.7 1.6 2.9 2 1 0 2 2 2 0 YmaF family FliD_N PF02465.18 EAX64743.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX64743.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DNA_pol_B_2 PF03175.13 EAX64744.1 - 7.6e-23 81.1 4.7 9.7e-23 80.8 4.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64744.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) VirE PF05272.11 EAX64745.1 - 8.8e-06 25.6 0.1 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX64745.1 - 0.018 14.1 1.4 0.061 12.4 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX64745.1 - 0.087 13.2 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 RNA helicase PSP PF04046.16 EAX64746.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX64747.1 - 0.045 14.2 0.3 0.084 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64747.1 - 0.46 10.6 3.3 9.9 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX64749.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX64749.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4108 PF13390.6 EAX64751.1 - 1.6e-39 135.1 1.7 1.8e-39 135.0 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX64751.1 - 0.12 11.4 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Btz PF09405.10 EAX64754.1 - 0.17 12.2 4.6 0.24 11.6 4.6 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX64754.1 - 0.37 10.7 2.2 0.72 9.8 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX64755.1 - 4.1e-58 195.4 4.2 4.5e-58 195.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX64756.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64758.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64759.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX64761.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64761.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64761.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64761.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64761.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64761.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64761.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64761.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX64761.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64761.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64761.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64761.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX64762.1 - 1.8e-08 33.7 2.4 1.8e-08 33.7 1.3 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX64762.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX64762.1 - 0.12 12.4 0.0 0.8 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX64762.1 - 0.22 10.2 1.9 2.6 6.7 1.9 2.3 1 1 0 1 1 1 0 DNA polymerase family B TMP PF05017.14 EAX64763.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX64767.1 - 2.4e-32 111.3 0.1 6.6e-19 68.3 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX64767.1 - 5.4e-22 77.6 0.0 1.6e-08 34.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX64767.1 - 6.7e-20 71.2 0.0 2.2e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX64767.1 - 2.9e-15 55.9 0.0 2.6e-06 27.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX64767.1 - 8.8e-14 50.3 0.0 0.01 16.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Amidase02_C PF12123.8 EAX64768.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX64768.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_D5 PF03288.16 EAX64769.1 - 3.2e-05 24.3 2.4 0.0002 21.8 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX64771.1 - 2.9e-157 521.3 11.5 3.6e-157 521.1 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX64771.1 - 0.084 13.2 1.3 9.2 6.7 0.1 3.5 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX64771.1 - 0.089 13.3 4.5 2.1 8.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX64773.1 - 1.4e-135 450.4 9.2 1.6e-135 450.2 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) EF-hand_2 PF09068.11 EAX64773.1 - 0.025 14.7 1.9 0.084 13.0 1.9 1.8 1 1 0 1 1 1 0 EF hand Podoplanin PF05808.11 EAX64774.1 - 0.00072 19.7 2.2 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 1 Podoplanin Mid2 PF04478.12 EAX64774.1 - 0.00096 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX64774.1 - 0.0012 18.5 1.9 0.0022 17.7 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 EAX64774.1 - 0.0033 17.6 2.9 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycophorin A Orf78 PF06024.12 EAX64774.1 - 0.0039 17.5 0.2 0.16 12.3 0.0 2.8 3 0 0 3 3 3 1 Orf78 (ac78) TMEM154 PF15102.6 EAX64774.1 - 0.0065 16.4 4.8 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.20 EAX64774.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain ECSCR PF15820.5 EAX64774.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MMM1 PF10296.9 EAX64774.1 - 0.11 11.6 1.3 0.33 9.9 0.1 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 MtrF PF09472.10 EAX64774.1 - 0.11 11.9 3.5 0.21 11.0 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Otopetrin PF03189.13 EAX64774.1 - 0.11 11.3 0.0 0.47 9.2 0.0 1.8 2 0 0 2 2 2 0 Otopetrin PsbW PF07123.12 EAX64774.1 - 0.12 12.4 0.6 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) EphA2_TM PF14575.6 EAX64774.1 - 0.12 13.2 0.1 0.39 11.6 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain PhoD_N PF16655.5 EAX64774.1 - 0.4 11.2 2.7 0.99 10.0 0.4 2.3 1 1 1 2 2 2 0 PhoD-like phosphatase, N-terminal domain Chordopox_G3 PF06129.12 EAX64774.1 - 0.47 11.2 1.8 4.8 7.9 0.1 2.5 3 0 0 3 3 2 0 Chordopoxvirus G3 protein DUF4330 PF14221.6 EAX64774.1 - 1.4 9.1 7.1 5.8 7.1 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) GGDEF PF00990.21 EAX64776.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX64776.1 - 9.6 6.2 6.6 20 5.2 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PSP PF04046.16 EAX64777.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64778.1 - 0.069 13.7 4.7 11 7.2 0.2 3.2 3 1 0 3 3 3 0 TMP repeat Rsa3 PF14615.6 EAX64779.1 - 1.3 8.7 3.6 23 4.6 0.3 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF2897 PF11446.8 EAX64780.1 - 0.061 13.2 3.0 0.11 12.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX64780.1 - 0.098 13.1 0.4 0.12 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX64781.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF5623 PF18536.1 EAX64782.1 - 0.047 14.0 0.1 0.059 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) DUF3839 PF12943.7 EAX64783.1 - 7.1e-95 317.1 7.4 8.3e-95 316.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX64783.1 - 0.031 13.8 0.3 0.034 13.7 0.3 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX64783.1 - 0.15 12.7 1.7 0.95 10.1 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF2207 PF09972.9 EAX64787.1 - 0.0031 16.3 2.4 0.0036 16.2 2.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RIFIN PF02009.16 EAX64787.1 - 0.017 15.0 5.3 0.021 14.7 5.3 1.1 1 0 0 1 1 1 0 Rifin DUF5305 PF17231.2 EAX64787.1 - 0.054 12.9 7.9 0.043 13.2 6.7 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 EAX64787.1 - 0.12 12.2 4.5 0.26 11.0 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Mid2 PF04478.12 EAX64789.1 - 0.00087 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX64789.1 - 0.00097 18.8 2.0 0.0016 18.1 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX64789.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX64789.1 - 0.0044 17.3 0.3 0.11 12.8 0.2 2.3 2 1 0 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 EAX64789.1 - 0.0059 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 EAX64789.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 EAX64789.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain DUF2207 PF09972.9 EAX64789.1 - 0.029 13.1 0.1 0.11 11.3 0.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 EAX64789.1 - 0.043 13.6 0.1 0.069 12.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX64789.1 - 0.056 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF3827 PF12877.7 EAX64789.1 - 0.083 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 EAX64789.1 - 0.086 13.7 0.1 0.28 12.1 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 EAX64789.1 - 0.088 12.2 3.5 0.15 11.4 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MMM1 PF10296.9 EAX64789.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ABC2_membrane_3 PF12698.7 EAX64789.1 - 0.15 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PTP_tm PF18861.1 EAX64789.1 - 0.17 11.8 1.1 0.36 10.8 0.4 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 EAX64789.1 - 0.53 9.7 5.7 1 8.8 5.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Trypan_PARP PF05887.11 EAX64790.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 EAX64791.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) T5orf172 PF10544.9 EAX64793.1 - 3.4e-07 30.8 0.3 6.8e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF2939 PF11159.8 EAX64794.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64794.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX64795.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX64795.1 - 0.047 13.7 0.6 0.069 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX64796.1 - 5.2e-07 29.4 2.1 5.2e-07 29.4 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64796.1 - 3.3e-05 24.2 0.3 0.00023 21.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64796.1 - 7.2e-05 22.6 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64796.1 - 0.00011 22.2 3.0 0.00026 21.0 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64796.1 - 0.00073 19.4 0.1 0.0014 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX64796.1 - 0.0015 18.2 0.5 0.015 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX64796.1 - 0.0019 18.0 1.0 0.0079 16.0 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64796.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX64796.1 - 0.062 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64796.1 - 0.076 13.4 0.1 0.53 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64796.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein APG12 PF04110.13 EAX64796.1 - 1.4 9.4 4.9 0.52 10.7 1.1 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_pol_B PF00136.21 EAX64797.1 - 0.083 11.6 0.5 0.096 11.4 0.5 1.1 1 0 0 1 1 1 0 DNA polymerase family B DNA_pol_B_2 PF03175.13 EAX64800.1 - 1.2e-16 60.6 2.9 2.2e-16 59.8 2.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64800.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein ResIII PF04851.15 EAX64801.1 - 5.7e-05 23.2 2.7 0.00011 22.2 2.7 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64801.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64801.1 - 0.00038 20.8 0.0 0.00063 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64801.1 - 0.00074 19.4 0.9 0.0025 17.7 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64801.1 - 0.0069 16.7 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64801.1 - 0.025 14.3 0.2 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX64801.1 - 0.038 13.4 0.1 0.059 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX64801.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX64801.1 - 0.23 11.7 4.9 4.6 7.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX64804.1 - 1.6e-17 63.5 3.7 2.6e-17 62.8 3.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64804.1 - 0.079 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF2486 PF10667.9 EAX64805.1 - 0.036 14.3 25.4 0.031 14.5 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Pox_D5 PF03288.16 EAX64807.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX64808.1 - 2.4e-52 176.7 5.2 2.6e-52 176.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX64809.1 - 7.8e-06 25.9 7.8 1.2e-05 25.3 0.6 2.6 3 0 0 3 3 3 2 Phage tail repeat like Phage_fiber PF03335.13 EAX64809.1 - 0.093 12.9 0.6 0.093 12.9 0.6 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX64809.1 - 0.35 11.4 3.1 4.3 7.9 1.7 2.7 2 1 0 2 2 2 0 YmaF family Amidase02_C PF12123.8 EAX64811.1 - 0.0023 17.6 0.1 0.0097 15.6 0.0 2.1 3 0 0 3 3 3 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX64813.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Mid2 PF04478.12 EAX64814.1 - 0.00021 21.1 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX64814.1 - 0.00022 20.9 2.0 0.00034 20.3 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX64814.1 - 0.00067 19.8 0.0 0.00078 19.6 0.0 1.1 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 EAX64814.1 - 0.0013 19.0 0.3 0.0015 18.8 0.3 1.2 1 1 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 EAX64814.1 - 0.0016 18.3 0.4 0.0023 17.8 0.3 1.3 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX64814.1 - 0.0019 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain ECSCR PF15820.5 EAX64814.1 - 0.0051 16.6 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DUF3827 PF12877.7 EAX64814.1 - 0.016 13.6 0.0 0.016 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Orf78 PF06024.12 EAX64814.1 - 0.021 15.1 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 EAX64814.1 - 0.027 15.3 0.0 0.047 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 EAX64814.1 - 0.029 13.4 0.1 0.039 13.0 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Gemini_mov PF01708.16 EAX64814.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 Geminivirus putative movement protein SKG6 PF08693.10 EAX64814.1 - 0.032 13.7 3.9 0.058 12.8 3.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MtrF PF09472.10 EAX64814.1 - 0.033 13.6 3.5 0.033 13.6 3.5 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PTP_tm PF18861.1 EAX64814.1 - 0.033 14.2 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Otopetrin PF03189.13 EAX64814.1 - 0.046 12.6 0.0 0.046 12.6 0.0 1.0 1 0 0 1 1 1 0 Otopetrin DUF4448 PF14610.6 EAX64814.1 - 0.057 13.2 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ODV-E18 PF10717.9 EAX64814.1 - 0.058 13.3 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5385 PF17359.2 EAX64814.1 - 0.063 12.8 0.2 0.36 10.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Cortexin PF11057.8 EAX64814.1 - 0.066 13.1 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney DUF2207 PF09972.9 EAX64814.1 - 0.087 11.6 0.0 0.087 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 EAX64814.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Amnionless PsbW PF07123.12 EAX64814.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) YukC PF10140.9 EAX64814.1 - 0.13 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF5305 PF17231.2 EAX64814.1 - 0.14 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Stevor PF17410.2 EAX64814.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM192 PF14802.6 EAX64814.1 - 0.18 10.9 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family ASFV_J13L PF05568.11 EAX64814.1 - 0.37 10.5 1.2 0.48 10.2 1.2 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein DDE_Tnp_ISL3 PF01610.17 EAX64815.1 - 0.048 13.4 0.1 0.048 13.4 0.1 1.7 2 0 0 2 2 2 0 Transposase DUF4106 PF13388.6 EAX64816.1 - 6.6e-123 411.0 15.3 6.6e-123 411.0 15.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF641 PF04859.12 EAX64817.1 - 0.031 14.6 1.7 0.045 14.1 1.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX64817.1 - 0.17 12.0 6.7 0.44 10.7 0.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF2960 PF11173.8 EAX64818.1 - 0.042 14.3 0.3 0.11 13.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) DUF3839 PF12943.7 EAX64819.1 - 3.7e-153 507.9 11.3 4.3e-153 507.7 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX64819.1 - 0.29 11.6 4.0 8 7.0 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX64820.1 - 1.3e-14 53.9 1.8 2.4e-14 53.1 1.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64820.1 - 0.013 14.9 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX64820.1 - 0.067 13.3 0.7 0.64 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Noggin PF05806.12 EAX64821.1 - 0.094 12.6 1.0 0.12 12.3 1.0 1.1 1 0 0 1 1 1 0 Noggin Paf1 PF03985.13 EAX64821.1 - 0.52 9.3 8.0 0.63 9.0 8.0 1.0 1 0 0 1 1 1 0 Paf1 ResIII PF04851.15 EAX64823.1 - 4.3e-05 23.6 2.2 8.1e-05 22.7 2.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64823.1 - 0.00032 20.5 0.0 0.0004 20.2 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64823.1 - 0.00036 20.8 0.0 0.00057 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64823.1 - 0.00084 19.2 0.9 0.0023 17.8 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64823.1 - 0.0064 16.8 0.0 0.0084 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64823.1 - 0.038 13.4 0.1 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX64823.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX64823.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX64823.1 - 0.23 11.2 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX64823.1 - 0.28 11.4 4.6 4.2 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX64824.1 - 1.1e-11 44.3 0.2 2.6e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64824.1 - 0.0083 15.5 0.6 0.011 15.0 0.6 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF2960 PF11173.8 EAX64825.1 - 0.037 14.5 0.3 0.082 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) TMP PF05017.14 EAX64826.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64827.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TFCD_C PF12612.8 EAX64828.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF1493 PF07377.12 EAX64829.1 - 0.027 15.0 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX64829.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Gly-zipper_Omp PF13488.6 EAX64830.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX64830.1 - 0.5 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TMP PF05017.14 EAX64831.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX64833.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64833.1 - 0.075 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX64834.1 - 5.4e-52 175.5 5.4 6e-52 175.4 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX64836.1 - 0.021 15.3 0.8 0.04 14.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SH3BGR PF04908.15 EAX64837.1 - 0.089 13.0 0.9 0.14 12.3 0.9 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein ResIII PF04851.15 EAX64838.1 - 2.3e-05 24.5 0.1 2.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64838.1 - 0.00038 20.3 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX64838.1 - 0.0017 18.6 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX64838.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64838.1 - 0.0062 16.9 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX64838.1 - 0.032 13.7 0.0 0.05 13.0 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX64838.1 - 0.053 13.3 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX64838.1 - 0.079 12.5 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX64838.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain T5orf172 PF10544.9 EAX64839.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX64840.1 - 4.8e-124 412.6 7.3 5.4e-124 412.4 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX64840.1 - 0.1 12.1 1.6 0.15 11.5 0.5 1.6 1 1 1 2 2 2 0 Z1 domain KilA-N PF04383.13 EAX64843.1 - 5.8e-41 138.9 0.1 5.8e-41 138.9 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX64843.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX64843.1 - 0.033 13.4 0.1 0.12 11.6 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX64843.1 - 0.1 11.2 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF1493 PF07377.12 EAX64844.1 - 0.031 14.7 0.8 0.063 13.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) BRO1 PF03097.18 EAX64846.1 - 0.028 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX64846.1 - 0.19 12.0 4.8 2 8.8 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX64846.1 - 0.5 10.9 3.1 2.8 8.5 1.7 2.4 2 1 1 3 3 3 0 YmaF family DUF2939 PF11159.8 EAX64848.1 - 0.017 15.5 0.5 0.021 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64848.1 - 1.4 8.9 5.8 1.5 8.8 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX64848.1 - 1.5 7.8 2.7 1.6 7.7 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF2400 PF09674.10 EAX64849.1 - 0.028 14.4 0.6 0.037 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) FAS_N PF17828.1 EAX64850.1 - 0.009 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta NurA PF09376.10 EAX64851.1 - 0.0078 15.9 0.6 0.009 15.7 0.6 1.1 1 0 0 1 1 1 1 NurA domain MetOD2 PF18548.1 EAX64851.1 - 0.025 14.7 1.4 0.025 14.7 1.4 2.7 2 1 0 2 2 2 0 Metanogen output domain 2 Citrate_bind PF16114.5 EAX64851.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding CENP-O PF09496.10 EAX64851.1 - 4.2 7.3 8.5 4 7.4 2.7 2.2 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component PadR PF03551.14 EAX64853.1 - 0.086 12.8 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX64854.1 - 2.2e-34 117.7 0.1 3e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX64854.1 - 0.095 12.7 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PSP PF04046.16 EAX64857.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PRA-PH PF01503.17 EAX64859.1 - 0.088 13.3 1.6 3.9 8.0 2.8 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4107 PF13389.6 EAX64861.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX64862.1 - 0.004 16.8 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX64863.1 - 0.0074 16.3 0.4 0.0098 15.9 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HI0933_like PF03486.14 EAX64863.1 - 0.27 9.9 0.9 0.34 9.6 0.9 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF2939 PF11159.8 EAX64864.1 - 0.02 15.3 0.6 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX64864.1 - 1.6 7.7 4.1 1.7 7.6 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX64864.1 - 4.4 7.3 7.6 4.7 7.2 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2897 PF11446.8 EAX64865.1 - 0.059 13.3 2.9 0.08 12.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OAD_gamma PF04277.13 EAX64865.1 - 4 8.1 4.1 4.2 8.0 4.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3839 PF12943.7 EAX64867.1 - 6e-115 382.8 3.8 6.8e-115 382.6 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX64867.1 - 0.078 13.0 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc binding domain WASH_WAHD PF11945.8 EAX64868.1 - 0.0029 17.2 1.3 0.068 12.7 0.2 1.9 1 1 1 2 2 2 2 WAHD domain of WASH complex Muted PF14942.6 EAX64868.1 - 0.004 17.5 0.7 0.59 10.5 0.0 2.0 2 0 0 2 2 2 2 Organelle biogenesis, Muted-like protein Mst1_SARAH PF11629.8 EAX64868.1 - 0.2 11.8 2.3 14 5.9 0.1 2.3 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Rsa3 PF14615.6 EAX64868.1 - 0.49 10.0 3.3 14 5.3 0.3 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 HD_2 PF12917.7 EAX64872.1 - 0.091 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Pox_A32 PF04665.12 EAX64873.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX64874.1 - 3.6e-08 33.2 1.2 4.1e-08 33.0 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64874.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64874.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64874.1 - 0.088 12.8 0.3 0.7 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX64876.1 - 2.2e-06 27.3 0.8 2.4e-06 27.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX64876.1 - 0.0027 16.6 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX64876.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX64876.1 - 0.022 14.7 0.7 0.047 13.7 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX64876.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64876.1 - 0.085 12.8 0.2 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX64876.1 - 0.22 11.7 1.8 1.7 8.9 0.1 2.5 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Amidase02_C PF12123.8 EAX64877.1 - 0.0097 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_D5 PF03288.16 EAX64878.1 - 1.5e-05 25.4 2.8 8.4e-05 23.0 2.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX64878.1 - 0.077 13.6 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX64878.1 - 0.099 12.6 0.3 0.15 12.0 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX64879.1 - 6.8e-64 214.1 7.1 7.6e-64 214.0 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX64881.1 - 5.7e-07 29.9 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX64881.1 - 0.046 14.4 0.1 0.094 13.4 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF1493 PF07377.12 EAX64882.1 - 0.027 15.0 1.0 0.055 13.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) YmaF PF12788.7 EAX64883.1 - 0.18 12.3 1.7 5.8 7.5 0.1 2.0 1 1 0 1 1 1 0 YmaF family KilA-N PF04383.13 EAX64884.1 - 4.2e-25 87.8 0.9 7.5e-25 87.0 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX64884.1 - 0.0037 17.4 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF4108 PF13390.6 EAX64885.1 - 2.2e-62 209.2 6.2 2.5e-62 209.1 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX64886.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF2897 PF11446.8 EAX64890.1 - 1.1 9.2 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PSP PF04046.16 EAX64892.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX64893.1 - 0.031 14.8 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX64894.1 - 1.2e-06 29.0 0.1 2.2e-06 28.1 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain HD_3 PF13023.6 EAX64896.1 - 0.055 13.4 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 HD domain La PF05383.17 EAX64896.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 La domain AAA_11 PF13086.6 EAX64897.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX64897.1 - 0.0023 18.2 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX64897.1 - 0.0033 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX64897.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX64897.1 - 0.021 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX64897.1 - 0.05 13.2 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX64897.1 - 0.085 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EAX64897.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 EAX64897.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein PTR PF12789.7 EAX64900.1 - 2.1e-05 24.5 0.6 2.1e-05 24.5 0.6 3.2 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX64900.1 - 0.014 14.7 0.8 0.021 14.1 0.8 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF445 PF04286.12 EAX64900.1 - 0.018 14.8 1.2 0.025 14.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX64900.1 - 0.03 13.9 7.0 0.071 12.7 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX64900.1 - 0.073 13.5 0.5 0.26 11.7 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX64900.1 - 0.11 12.2 0.1 8.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 PKcGMP_CC PF16808.5 EAX64900.1 - 7.9 6.4 7.7 3.5 7.6 0.4 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MULE PF10551.9 EAX64901.1 - 1.1e-10 41.8 1.0 1.7e-10 41.1 0.2 1.7 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX64901.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Amidase02_C PF12123.8 EAX64902.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX64902.1 - 0.2 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX64904.1 - 2.7e-48 163.5 4.6 3e-48 163.4 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX64905.1 - 3.4e-05 24.2 2.1 0.00015 22.2 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX64905.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Ank_2 PF12796.7 EAX64907.1 - 1.3e-26 93.0 2.8 4.6e-16 59.2 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX64907.1 - 1.8e-20 73.0 1.2 4.3e-07 30.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX64907.1 - 1.6e-16 58.7 0.2 6.6e-06 26.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX64907.1 - 6.4e-16 58.0 0.7 6.9e-06 26.3 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX64907.1 - 5e-14 52.2 0.3 2.2e-08 34.2 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RGP PF03214.13 EAX64907.1 - 0.067 12.3 0.0 3 6.9 0.0 2.0 1 1 1 2 2 2 0 Reversibly glycosylated polypeptide MetallophosN PF16371.5 EAX64907.1 - 0.078 13.3 0.0 16 5.9 0.0 2.5 1 1 2 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Stap_Strp_toxin PF01123.20 EAX64907.1 - 0.12 13.3 0.3 6.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF4378 PF14309.6 EAX64908.1 - 0.026 14.9 0.1 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) DUF2960 PF11173.8 EAX64909.1 - 0.047 14.1 0.3 0.11 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) DUF2897 PF11446.8 EAX64910.1 - 0.64 9.9 2.6 1.4 8.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX64911.1 - 9.1e-05 22.9 2.1 0.0005 20.5 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PTR PF12789.7 EAX64912.1 - 2.3e-05 24.4 0.6 2.3e-05 24.4 0.6 3.9 3 1 0 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX64912.1 - 0.015 15.1 6.5 0.024 14.4 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX64912.1 - 0.032 13.9 1.0 2.2 8.0 0.6 2.5 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX64912.1 - 0.057 13.9 3.0 0.13 12.7 0.0 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX64912.1 - 0.25 10.9 16.5 0.012 15.2 5.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX64914.1 - 0.023 15.2 0.7 0.041 14.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PapD_N PF00345.20 EAX64915.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX64915.1 - 0.078 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX64915.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RFX_DNA_binding PF02257.15 EAX64916.1 - 6.6e-05 23.5 0.2 9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX64916.1 - 0.00073 20.0 2.0 0.0011 19.4 2.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX64916.1 - 0.013 15.5 1.3 0.018 15.0 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF2897 PF11446.8 EAX64917.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX64918.1 - 0.0093 15.6 0.2 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX64919.1 - 1.5e-06 28.7 0.3 2.9e-06 27.7 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX64920.1 - 0.015 15.8 0.7 0.029 14.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) IstB_IS21 PF01695.17 EAX64921.1 - 2.1e-05 24.3 0.2 0.3 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX64921.1 - 4.8e-05 23.6 0.1 0.00038 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX64921.1 - 0.00019 21.0 2.3 0.00019 21.0 2.3 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX64921.1 - 0.0002 21.4 3.8 0.00034 20.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64921.1 - 0.00053 19.8 0.0 0.00097 18.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64921.1 - 0.0015 18.3 0.8 0.0033 17.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64921.1 - 0.0039 16.8 2.9 0.011 15.4 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64921.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX64921.1 - 0.056 13.5 0.9 0.94 9.5 0.9 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX64921.1 - 0.061 12.9 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX64921.1 - 0.066 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX64921.1 - 0.069 13.6 0.1 0.67 10.4 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64921.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64921.1 - 0.49 10.7 4.7 8.2 6.8 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX64921.1 - 4.8 7.9 11.1 0.21 12.2 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Trypan_PARP PF05887.11 EAX64922.1 - 0.055 13.4 10.3 0.086 12.8 10.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX64925.1 - 1e-39 136.3 2.9 1.1e-39 136.1 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64925.1 - 0.071 13.5 0.6 0.098 13.0 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3944 PF13099.6 EAX64927.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) DUF5330 PF17264.2 EAX64927.1 - 0.28 11.2 2.6 35 4.5 0.1 2.7 1 1 3 4 4 4 0 Family of unknown function (DUF5330) ENT PF03735.14 EAX64927.1 - 1.2 9.3 3.1 2e+02 2.1 0.0 3.7 1 1 3 4 4 4 0 ENT domain GPS2_interact PF15784.5 EAX64929.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX64929.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX64931.1 - 5.1e-21 75.1 6.2 6.1e-20 71.5 6.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64931.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_D5 PF03288.16 EAX64933.1 - 2.4e-05 24.7 2.1 0.00011 22.6 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX64933.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX64933.1 - 0.062 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Sec1 PF00995.23 EAX64934.1 - 4.5e-31 108.7 1.2 5.6e-31 108.4 1.2 1.1 1 0 0 1 1 1 1 Sec1 family GGDEF PF00990.21 EAX64937.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX64938.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX64938.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX64939.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64939.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64939.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64939.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX64940.1 - 5.8e-08 32.5 1.4 1e-07 31.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX64941.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64941.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64941.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64941.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64941.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64941.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64941.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64941.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX64941.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64941.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64941.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64941.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX64942.1 - 5.7e-07 29.2 2.1 5.7e-07 29.2 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX64942.1 - 3.1e-05 24.3 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX64942.1 - 6.3e-05 22.8 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX64942.1 - 0.00019 21.5 3.7 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX64942.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX64942.1 - 0.0012 18.6 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX64942.1 - 0.0017 18.0 0.4 0.01 15.5 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX64942.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX64942.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX64942.1 - 0.082 13.3 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX64942.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX64942.1 - 0.38 11.0 4.3 7.6 6.9 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX64943.1 - 2.3e-108 361.2 7.5 2.9e-108 360.9 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX64943.1 - 0.27 11.9 2.5 0.48 11.1 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DNA_pol_B_2 PF03175.13 EAX64944.1 - 1.4e-18 67.1 2.7 2.7e-18 66.1 2.7 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX64944.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein IKKbetaNEMObind PF12179.8 EAX64945.1 - 0.19 11.8 0.1 0.47 10.5 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF1493 PF07377.12 EAX64948.1 - 0.042 14.3 0.5 0.08 13.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2897 PF11446.8 EAX64949.1 - 2 8.4 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX64950.1 - 1.8e-16 59.9 2.5 1.8e-16 59.9 2.5 4.6 3 2 2 5 5 5 1 Phage tail repeat like DUF3391 PF11871.8 EAX64950.1 - 0.047 14.2 2.9 1 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX64950.1 - 3.5 7.2 18.2 0.24 11.0 5.3 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) HNH_3 PF13392.6 EAX64951.1 - 2e-07 30.6 0.1 3.6e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease TMP PF05017.14 EAX64953.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX64954.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX64955.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX64956.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX64956.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX64957.1 - 2.1e-07 30.6 2.6 3e-07 30.2 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64957.1 - 0.0047 16.6 0.2 0.0059 16.3 0.2 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX64957.1 - 0.06 12.8 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX64957.1 - 0.067 12.9 0.2 0.49 10.1 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX64957.1 - 0.094 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX64957.1 - 0.22 11.5 2.2 1.4 8.9 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX64957.1 - 0.65 10.2 8.5 5.9 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX64958.1 - 0.0021 17.7 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX64960.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64961.1 - 0.31 10.9 3.5 0.42 10.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX64962.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX64963.1 - 0.57 10.1 3.2 1.1 9.2 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2939 PF11159.8 EAX64965.1 - 0.038 14.4 0.5 0.038 14.4 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX64965.1 - 1.5 7.7 4.8 1.7 7.6 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX64965.1 - 2.9 7.9 8.2 3.2 7.7 8.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Asp-B-Hydro_N PF05279.11 EAX64965.1 - 6.2 6.8 17.2 6.7 6.7 17.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2400 PF09674.10 EAX64966.1 - 0.022 14.8 0.3 0.029 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX64966.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX64966.1 - 0.061 13.3 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX64967.1 - 6.7e-24 84.6 7.6 7.5e-23 81.1 7.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64967.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX64968.1 - 1.8e-55 188.0 4.3 2.1e-55 187.8 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX64968.1 - 0.032 13.7 0.2 0.035 13.6 0.2 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX64968.1 - 0.14 12.7 1.3 1.5 9.5 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX64969.1 - 3.9e-41 140.9 0.5 4.5e-41 140.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX64969.1 - 0.068 13.5 0.6 0.084 13.3 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX64971.1 - 5.2e-16 58.6 3.5 5.2e-16 58.6 3.5 1.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral TFCD_C PF12612.8 EAX64971.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Amidase02_C PF12123.8 EAX64973.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase HC2 PF07382.11 EAX64974.1 - 1.3e-07 31.9 12.4 1.5e-07 31.7 12.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX64974.1 - 4.2e-05 23.6 0.5 5.1e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Aurora-A_bind PF09041.10 EAX64974.1 - 0.96 9.6 8.7 2.3e+02 1.9 8.7 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX64974.1 - 1.8 8.6 5.1 71 3.5 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) DDE_1 PF03184.19 EAX64977.1 - 1.1e-10 41.5 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_B_2 PF03175.13 EAX64979.1 - 2.3e-10 40.0 2.9 1.1e-09 37.7 2.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX64979.1 - 0.091 12.8 0.0 0.71 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX64979.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Mito_fiss_reg PF05308.11 EAX64980.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX64980.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DDE_1 PF03184.19 EAX64981.1 - 4.7e-14 52.4 0.0 6.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 2_5_RNA_ligase2 PF13563.6 EAX64982.1 - 0.041 13.8 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Col_cuticle_N PF01484.17 EAX64982.1 - 0.21 11.7 0.1 0.5 10.5 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Pox_A32 PF04665.12 EAX64983.1 - 5.8e-08 32.5 1.3 7.3e-08 32.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX64983.1 - 0.0041 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX64983.1 - 0.046 13.4 0.1 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX64983.1 - 0.071 13.1 0.4 0.63 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX64984.1 - 7.3e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX64984.1 - 0.073 13.2 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers ZapB PF06005.12 EAX64984.1 - 0.17 12.3 0.9 0.71 10.3 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX64986.1 - 9.1e-35 118.9 0.1 2.1e-34 117.7 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX64986.1 - 0.02 15.5 0.0 0.049 14.2 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family RPAP3_C PF13877.6 EAX64986.1 - 0.044 14.3 0.1 0.098 13.2 0.1 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 LOH1CR12 PF10158.9 EAX64986.1 - 0.39 10.7 3.4 2.3 8.3 0.4 2.2 2 0 0 2 2 2 0 Tumour suppressor protein DUF2939 PF11159.8 EAX64987.1 - 0.002 18.5 0.3 0.0026 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX64987.1 - 0.089 12.8 0.1 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX64987.1 - 1.5 8.8 4.9 1.7 8.7 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX64988.1 - 7.3e-42 141.8 0.1 1e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF4106 PF13388.6 EAX64990.1 - 1.1e-44 153.3 3.6 1.2e-44 153.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DDR PF08841.10 EAX64991.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 EAX64992.1 - 1.1e-06 29.2 0.0 1.2e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX64992.1 - 1.9e-05 25.1 0.0 2.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX64992.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX64992.1 - 0.0051 17.2 0.0 0.058 14.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX64992.1 - 0.078 13.5 0.0 5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat PTR PF12789.7 EAX64993.1 - 3.1e-22 78.4 8.0 3.1e-22 78.4 8.0 3.7 2 1 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX64993.1 - 0.045 13.5 0.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DNA_pol_B_2 PF03175.13 EAX64994.1 - 8.8e-21 74.3 6.6 1e-19 70.8 6.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64994.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) KilA-N PF04383.13 EAX64995.1 - 3.3e-34 117.1 1.0 5.9e-34 116.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX64995.1 - 0.0033 18.0 0.1 0.01 16.5 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family DDE_Tnp_4 PF13359.6 EAX64997.1 - 1.2e-36 125.8 0.0 1.5e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX64997.1 - 6.2e-08 32.5 0.8 1.2e-06 28.4 0.8 2.1 1 1 0 1 1 1 1 Transposase DDE domain UCH PF00443.29 EAX64997.1 - 1.2e-06 28.2 0.3 8.2e-06 25.5 0.2 2.1 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX64997.1 - 0.00091 18.9 0.1 0.043 13.4 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1_2 PF13586.6 EAX64997.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain DNA_pol_B_2 PF03175.13 EAX64999.1 - 6.3e-11 41.8 0.9 1.6e-09 37.1 0.3 2.0 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX64999.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX64999.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4107 PF13389.6 EAX65000.1 - 4.5e-64 215.5 1.0 6.1e-64 215.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1043 PF06295.12 EAX65001.1 - 0.045 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX65001.1 - 0.083 12.9 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX65002.1 - 2.1e-30 106.0 6.1 2.8e-30 105.6 6.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Amidase02_C PF12123.8 EAX65003.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Transposase_mut PF00872.18 EAX65004.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family TMP PF05017.14 EAX65005.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX65008.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65010.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65011.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX65012.1 - 7.1e-06 26.0 2.4 1.3e-05 25.2 0.6 2.4 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX65012.1 - 0.0025 17.2 0.3 0.0032 16.8 0.3 1.1 1 0 0 1 1 1 1 M penetrans paralogue family 1 EDR1 PF14381.6 EAX65012.1 - 0.01 15.6 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Ethylene-responsive protein kinase Le-CTR1 DUF445 PF04286.12 EAX65012.1 - 0.01 15.7 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX65012.1 - 0.025 15.0 0.1 0.062 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX65012.1 - 0.046 13.3 3.5 0.14 11.7 3.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Amidase02_C PF12123.8 EAX65013.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX65013.1 - 0.22 11.4 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX65014.1 - 4.7e-07 29.5 0.0 6.8e-07 29.0 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX65016.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX65017.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX65017.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX65019.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65019.1 - 0.045 13.7 0.4 0.067 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX65019.1 - 0.12 12.4 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4106 PF13388.6 EAX65020.1 - 3.4e-21 76.0 3.7 3.4e-21 76.0 3.7 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX65020.1 - 0.29 9.7 4.5 0.37 9.3 4.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3452 PF11934.8 EAX65020.1 - 0.31 10.6 1.4 0.41 10.2 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX65020.1 - 6 6.8 6.1 0.99 9.4 1.4 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) PapD_N PF00345.20 EAX65021.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65021.1 - 0.07 13.1 0.5 0.1 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) GGDEF PF00990.21 EAX65022.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX65022.1 - 5.9 6.9 8.8 0.39 10.6 4.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65023.1 - 4.6e-64 214.7 5.7 5.1e-64 214.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX65024.1 - 3.9e-153 507.8 13.6 4.6e-153 507.6 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX65024.1 - 0.36 10.7 2.4 1.1 9.1 1.5 2.3 2 1 0 2 2 2 0 Nucleotidyltransferase APC_u14 PF16635.5 EAX65024.1 - 0.9 10.1 3.7 1.3 9.6 1.5 2.2 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX65024.1 - 4.4 7.8 7.3 1.7 9.1 0.4 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX65025.1 - 2.4e-10 39.9 0.3 5.2e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65025.1 - 0.039 13.2 0.3 0.06 12.6 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX65025.1 - 0.16 12.0 0.3 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Pox_D5 PF03288.16 EAX65026.1 - 7.2e-05 23.2 3.2 0.00046 20.6 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65026.1 - 0.041 14.5 0.2 0.083 13.5 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain BRO1 PF03097.18 EAX65034.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX65034.1 - 0.16 12.2 4.8 1.8 8.9 0.3 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX65034.1 - 0.2 12.2 1.8 2.9 8.5 1.8 2.2 1 1 1 2 2 2 0 YmaF family TMP PF05017.14 EAX65035.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65036.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Noggin PF05806.12 EAX65037.1 - 0.028 14.3 0.9 0.035 14.0 0.9 1.0 1 0 0 1 1 1 0 Noggin PSP PF04046.16 EAX65038.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ribosomal_60s PF00428.19 EAX65039.1 - 0.063 13.9 0.3 0.068 13.8 0.3 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein HTH_32 PF13565.6 EAX65040.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DNA_pol_B_2 PF03175.13 EAX65043.1 - 4.4e-10 39.0 2.9 7.6e-10 38.2 2.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX65044.1 - 1.9e-38 130.3 24.9 1.1e-32 111.8 13.7 4.2 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX65044.1 - 0.026 14.2 0.9 0.061 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Amidase02_C PF12123.8 EAX65045.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_D5 PF03288.16 EAX65046.1 - 0.00011 22.7 2.3 0.00054 20.4 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX65047.1 - 6.1e-44 149.4 2.1 6.8e-44 149.3 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX65048.1 - 3.2e-21 75.7 7.3 1.4e-20 73.6 7.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65048.1 - 0.042 13.8 0.0 0.6 10.1 0.0 2.7 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF3221 PF11518.8 EAX65050.1 - 0.012 16.0 0.6 0.035 14.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) KilA-N PF04383.13 EAX65053.1 - 2.7e-33 114.1 0.0 4.6e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX65053.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX65054.1 - 3e-07 30.9 0.4 6e-07 30.0 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain PapD_N PF00345.20 EAX65055.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain YmaF PF12788.7 EAX65056.1 - 0.16 12.5 2.3 2.5 8.7 2.3 2.1 1 1 0 1 1 1 0 YmaF family DUF2666 PF10869.8 EAX65057.1 - 0.013 15.7 1.7 0.024 14.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Ank_4 PF13637.6 EAX65060.1 - 1.2e-20 73.5 1.3 1.1e-10 41.8 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX65060.1 - 1.5e-17 63.9 0.2 3.8e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX65060.1 - 7.1e-14 51.7 0.2 7.5e-08 32.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX65060.1 - 4.4e-13 49.0 3.2 0.0045 17.4 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX65060.1 - 3.9e-12 45.2 1.4 0.0099 16.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF1493 PF07377.12 EAX65061.1 - 0.078 13.5 0.6 0.16 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX65062.1 - 8.5e-53 176.3 47.3 5.2e-33 112.9 18.9 4.2 3 2 1 4 4 4 2 Phage tail repeat like Apolipoprotein PF01442.18 EAX65062.1 - 0.00022 21.2 1.5 0.00041 20.3 1.5 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain RACo_linker PF17650.1 EAX65062.1 - 0.00073 19.4 0.6 0.31 10.9 0.1 3.2 2 1 1 3 3 3 1 RACo linker region PH_TFIIH PF08567.11 EAX65062.1 - 0.0042 17.4 9.3 1.4 9.3 0.2 4.2 1 1 3 4 4 4 2 TFIIH p62 subunit, N-terminal domain Peptidase_C78 PF07910.13 EAX65062.1 - 0.014 14.9 3.0 1.1 8.7 0.6 2.9 1 1 2 3 3 3 0 Peptidase family C78 DUF4116 PF13475.6 EAX65062.1 - 0.033 13.9 1.3 0.046 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PolyA_pol_arg_C PF12626.7 EAX65062.1 - 0.058 13.4 0.0 22 5.1 0.0 2.8 1 1 0 2 2 2 0 Polymerase A arginine-rich C-terminus GUN4_N PF16416.5 EAX65062.1 - 0.21 11.6 5.8 5.3 7.1 0.3 3.1 3 1 0 3 3 3 0 ARM-like repeat domain, GUN4-N terminal AviRa PF11599.8 EAX65062.1 - 0.27 10.7 6.4 0.39 10.1 1.3 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa SAS4 PF15460.6 EAX65062.1 - 3.1 8.0 16.3 14 5.9 0.2 3.4 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 Herpes_UL25 PF01499.16 EAX65064.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3839 PF12943.7 EAX65067.1 - 7.8e-154 510.1 11.5 9.6e-154 509.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX65067.1 - 0.025 14.2 1.3 0.091 12.4 0.2 2.5 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX65067.1 - 0.048 14.1 5.3 0.31 11.5 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX65067.1 - 0.095 13.1 1.4 0.23 11.9 0.2 1.9 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX65067.1 - 0.75 10.4 4.6 0.61 10.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Amidase02_C PF12123.8 EAX65069.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PBCV_basic_adap PF08789.10 EAX65070.1 - 0.011 15.9 1.3 4 7.6 0.9 3.0 2 1 0 2 2 2 0 PBCV-specific basic adaptor domain FAS_N PF17828.1 EAX65070.1 - 0.017 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Mito_fiss_reg PF05308.11 EAX65072.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65072.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2897 PF11446.8 EAX65073.1 - 1.9 8.4 3.7 3.9 7.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX65074.1 - 1.8e-16 60.1 2.0 2.4e-16 59.7 2.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65074.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Phage_fiber PF03335.13 EAX65075.1 - 1.1 9.6 6.3 5.9 7.3 0.7 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat TMP PF05017.14 EAX65077.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65078.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX65079.1 - 0.029 14.8 0.2 0.049 14.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65079.1 - 0.31 11.1 3.5 6.7 6.8 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Trypan_PARP PF05887.11 EAX65080.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65080.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMP PF05017.14 EAX65083.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65084.1 - 0.11 12.3 2.3 0.19 11.7 0.2 2.2 2 1 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX65085.1 - 9.4e-23 80.8 3.8 1.3e-22 80.3 3.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65085.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Trypan_PARP PF05887.11 EAX65086.1 - 0.022 14.8 8.5 0.034 14.1 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65086.1 - 3.4 8.1 4.9 4.9 7.6 4.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX65087.1 - 0.0003 20.4 2.6 0.00048 19.7 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65087.1 - 0.0042 16.8 0.2 0.0057 16.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX65087.1 - 0.03 13.8 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX65087.1 - 0.032 14.0 0.2 0.3 10.8 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX65087.1 - 0.053 13.3 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PTR PF12789.7 EAX65089.1 - 2.1e-11 43.7 2.6 2.1e-11 43.7 2.6 2.9 4 0 0 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX65089.1 - 0.19 12.3 9.2 3.2 8.3 1.6 3.2 2 2 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX65089.1 - 3.1 8.2 18.4 3 8.3 0.3 4.6 4 0 0 4 4 4 0 Phage tail fibre repeat IstB_IS21 PF01695.17 EAX65090.1 - 2.6e-05 24.1 0.4 0.29 10.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX65090.1 - 3.1e-05 24.3 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX65090.1 - 5.7e-05 22.7 1.9 5.7e-05 22.7 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX65090.1 - 0.00049 20.1 5.6 0.00067 19.7 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65090.1 - 0.00052 19.8 0.1 0.00096 19.0 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX65090.1 - 0.0052 16.5 3.0 0.014 15.1 0.2 2.6 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX65090.1 - 0.0058 16.5 0.9 0.0058 16.5 0.9 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX65090.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65090.1 - 0.067 12.8 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65090.1 - 0.071 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65090.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX65090.1 - 0.1 12.7 1.2 1.7 8.7 1.2 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX65090.1 - 0.23 11.8 5.1 3 8.2 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX65090.1 - 2.9 8.6 13.0 0.19 12.4 3.6 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 PSP PF04046.16 EAX65091.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65092.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65093.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65094.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX65095.1 - 1.8e-39 133.6 27.3 1.3e-32 111.6 13.1 3.9 4 1 1 5 5 5 2 Phage tail repeat like Herpes_UL25 PF01499.16 EAX65096.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Chromo PF00385.24 EAX65097.1 - 0.34 10.9 7.8 0.05 13.5 2.5 2.3 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_MLP1_2 PF07926.12 EAX65098.1 - 0.033 14.3 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX65098.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX65098.1 - 0.098 12.6 2.7 0.098 12.6 2.7 2.1 2 1 0 2 2 2 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX65102.1 - 4.1e-16 58.9 2.3 5e-16 58.6 2.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65102.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Mito_fiss_reg PF05308.11 EAX65103.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65103.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PTR PF12789.7 EAX65104.1 - 0.0077 16.3 0.1 0.0077 16.3 0.1 4.6 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX65104.1 - 0.008 15.8 5.9 0.049 13.2 5.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX65104.1 - 0.67 10.5 4.3 40 4.8 0.1 3.1 2 1 0 3 3 3 0 YmaF family AAA_22 PF13401.6 EAX65105.1 - 6e-05 23.3 0.1 0.0004 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65105.1 - 8.9e-05 22.3 0.4 0.58 9.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65105.1 - 0.00017 21.7 3.6 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65105.1 - 0.00052 19.8 0.1 0.00096 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX65105.1 - 0.0014 18.1 1.8 0.0014 18.1 1.8 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX65105.1 - 0.0017 18.2 0.9 0.0065 16.3 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65105.1 - 0.0053 16.4 2.6 0.013 15.2 0.2 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65105.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX65105.1 - 0.052 13.1 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX65105.1 - 0.064 12.8 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65105.1 - 0.069 13.6 0.1 0.64 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65105.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65105.1 - 1.1 9.5 5.8 13 6.1 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX65105.1 - 6.4 7.5 10.1 0.64 10.7 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Trypan_PARP PF05887.11 EAX65107.1 - 0.036 14.1 8.3 0.056 13.4 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65107.1 - 2.5 8.5 5.3 3.6 8.0 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF257 PF03192.13 EAX65108.1 - 0.00097 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65108.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF1031 PF06275.11 EAX65109.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX65109.1 - 0.034 14.2 0.3 0.16 12.1 0.2 1.9 1 1 1 2 2 2 0 Annexin HARE-HTH PF05066.13 EAX65109.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Amidase02_C PF12123.8 EAX65110.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX65111.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MG2 PF01835.19 EAX65112.1 - 2.9e-05 24.4 0.6 0.0047 17.3 0.1 2.4 2 1 0 2 2 2 1 MG2 domain DUF4625 PF15418.6 EAX65112.1 - 6.6e-05 23.2 1.7 0.014 15.6 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX65112.1 - 0.0048 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Chitinase A, N-terminal domain DUF2914 PF11141.8 EAX65112.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) NPCBM_assoc PF10633.9 EAX65112.1 - 0.022 15.0 5.7 0.048 13.9 0.2 3.3 3 2 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase RIFIN PF02009.16 EAX65112.1 - 0.065 13.1 7.6 0.088 12.7 7.6 1.2 1 0 0 1 1 1 0 Rifin PKD PF00801.20 EAX65112.1 - 0.079 12.8 0.2 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 PKD domain Amnionless PF14828.6 EAX65112.1 - 0.11 11.3 0.2 0.16 10.7 0.2 1.3 1 0 0 1 1 1 0 Amnionless DUF5305 PF17231.2 EAX65112.1 - 0.14 11.5 10.3 0.06 12.7 7.8 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5305) He_PIG PF05345.12 EAX65112.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.7 3 0 0 3 3 3 0 Putative Ig domain Lipocalin PF00061.23 EAX65112.1 - 1.3 9.2 8.9 0.081 13.1 2.0 2.1 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Amidase02_C PF12123.8 EAX65113.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX65115.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TMP PF05017.14 EAX65116.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65117.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX65118.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX65121.1 - 5.2e-69 231.5 2.1 6.2e-69 231.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX65121.1 - 0.056 13.8 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX65123.1 - 4.8e-38 130.9 3.0 5.4e-38 130.7 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX65123.1 - 0.071 13.5 0.7 0.086 13.2 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta RFX_DNA_binding PF02257.15 EAX65125.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX65125.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX65125.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain TMP PF05017.14 EAX65126.1 - 0.15 12.8 6.3 11 7.2 0.2 3.4 3 1 1 4 4 4 0 TMP repeat KilA-N PF04383.13 EAX65127.1 - 1e-15 57.6 0.6 2.7e-15 56.2 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX65127.1 - 0.0026 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) YmaF PF12788.7 EAX65128.1 - 0.22 12.1 2.1 13 6.4 0.2 2.2 1 1 1 2 2 2 0 YmaF family AAA_22 PF13401.6 EAX65129.1 - 6.8e-05 23.2 0.0 0.00039 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65129.1 - 7e-05 22.9 3.3 0.00013 22.0 3.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65129.1 - 0.0003 20.6 0.0 0.00043 20.1 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65129.1 - 0.00062 19.6 0.6 0.0016 18.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65129.1 - 0.0031 17.2 0.3 0.3 10.8 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65129.1 - 0.0077 16.6 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65129.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65129.1 - 0.051 13.3 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX65129.1 - 0.054 13.1 0.4 0.12 12.0 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA PF00004.29 EAX65129.1 - 0.095 13.1 0.1 0.4 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65129.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65129.1 - 0.17 12.2 4.2 4.1 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) NMT PF01233.19 EAX65130.1 - 0.09 12.6 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain BRO1 PF03097.18 EAX65131.1 - 0.039 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX65131.1 - 5.6 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat PTR PF12789.7 EAX65133.1 - 4.1e-06 26.8 1.3 4.1e-06 26.8 1.3 3.5 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX65133.1 - 0.0015 18.2 4.7 0.19 11.3 1.4 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX65133.1 - 0.66 10.6 3.3 15 6.2 1.7 2.8 2 1 1 3 3 3 0 YmaF family DNA_pol_B_2 PF03175.13 EAX65136.1 - 1.1e-22 80.5 4.0 1.9e-22 79.8 4.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral La PF05383.17 EAX65137.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 La domain GGDEF PF00990.21 EAX65138.1 - 0.066 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX65138.1 - 0.68 9.9 3.8 1.5 8.8 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX65139.1 - 5.2e-25 87.5 0.6 1.6e-24 85.9 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain GPS2_interact PF15784.5 EAX65140.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DNA_pol_B_2 PF03175.13 EAX65143.1 - 2.3e-22 79.5 5.8 2.4e-21 76.2 5.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65143.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) FAS_N PF17828.1 EAX65144.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65145.1 - 0.0085 16.5 0.2 0.0094 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) DUF4107 PF13389.6 EAX65146.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX65147.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65147.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX65147.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX65147.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX65147.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX65147.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX65147.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PBP_sp32 PF07222.12 EAX65148.1 - 2.3 7.6 10.2 2.6 7.4 10.2 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4108 PF13390.6 EAX65149.1 - 3.2e-61 205.5 8.5 3.5e-61 205.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX65149.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide FAS_N PF17828.1 EAX65150.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Mid2 PF04478.12 EAX65151.1 - 0.00019 21.3 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX65151.1 - 0.00031 20.4 2.0 0.00048 19.8 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX65151.1 - 0.00076 19.6 0.0 0.00088 19.4 0.0 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX65151.1 - 0.0024 17.8 0.7 0.0026 17.7 0.7 1.4 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX65151.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX65151.1 - 0.0028 17.9 0.9 0.004 17.4 0.9 1.4 1 1 0 1 1 1 1 Glycophorin A ECSCR PF15820.5 EAX65151.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 EAX65151.1 - 0.013 15.7 0.1 0.018 15.3 0.1 1.3 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX65151.1 - 0.025 14.3 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MtrF PF09472.10 EAX65151.1 - 0.028 13.8 3.5 0.046 13.1 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 EAX65151.1 - 0.033 15.1 0.1 0.069 14.0 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 EAX65151.1 - 0.037 13.1 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Gemini_mov PF01708.16 EAX65151.1 - 0.04 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein PTP_tm PF18861.1 EAX65151.1 - 0.042 13.8 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 EAX65151.1 - 0.051 13.0 4.0 0.091 12.2 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Otopetrin PF03189.13 EAX65151.1 - 0.056 12.3 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Otopetrin DUF2207 PF09972.9 EAX65151.1 - 0.063 12.0 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5385 PF17359.2 EAX65151.1 - 0.078 12.5 0.3 0.56 9.7 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Cortexin PF11057.8 EAX65151.1 - 0.094 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney ODV-E18 PF10717.9 EAX65151.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 EAX65151.1 - 0.1 10.9 2.3 0.11 10.9 1.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Amnionless PF14828.6 EAX65151.1 - 0.14 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless PsbW PF07123.12 EAX65151.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) YukC PF10140.9 EAX65151.1 - 0.27 10.0 0.0 0.27 10.0 0.0 1.4 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC ASFV_J13L PF05568.11 EAX65151.1 - 3.6 7.3 5.2 1.9 8.2 2.0 1.8 1 1 1 2 2 2 0 African swine fever virus J13L protein YmaF PF12788.7 EAX65152.1 - 0.11 13.1 1.4 1.3 9.6 1.4 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX65152.1 - 0.61 10.4 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX65153.1 - 5.9e-48 160.8 37.8 1.3e-30 105.2 16.8 3.9 2 2 1 3 3 3 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX65153.1 - 0.013 15.8 8.5 2.3 8.6 0.3 4.4 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF4116 PF13475.6 EAX65153.1 - 0.019 14.7 1.1 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Peptidase_C78 PF07910.13 EAX65153.1 - 0.022 14.3 1.8 4 6.9 0.3 2.7 1 1 2 3 3 3 0 Peptidase family C78 GUN4_N PF16416.5 EAX65153.1 - 0.14 12.2 2.5 7.2 6.7 0.2 3.1 1 1 2 3 3 3 0 ARM-like repeat domain, GUN4-N terminal UL16 PF17622.2 EAX65153.1 - 0.14 11.8 0.8 0.73 9.5 0.0 2.1 2 1 0 2 2 2 0 Viral unique long protein 16 Peptidase_S66 PF02016.15 EAX65153.1 - 0.14 12.3 1.4 23 5.1 0.2 3.1 1 1 2 3 3 3 0 LD-carboxypeptidase N-terminal domain YodL PF14191.6 EAX65153.1 - 0.89 10.4 5.8 16 6.4 0.1 3.4 2 1 2 4 4 4 0 YodL-like SAS4 PF15460.6 EAX65153.1 - 1.3 9.2 12.9 5.8 7.1 0.2 2.9 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 BshC PF10079.9 EAX65153.1 - 2.4 6.8 13.6 0.48 9.1 9.2 1.8 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC MULE PF10551.9 EAX65155.1 - 1.6e-11 44.5 0.1 2.8e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX65155.1 - 0.09 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 PWI domain DUF4108 PF13390.6 EAX65156.1 - 5.1e-47 159.4 4.1 5.6e-47 159.3 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX65157.1 - 1e-42 145.4 3.0 1.1e-42 145.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65157.1 - 0.13 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF2897 PF11446.8 EAX65158.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2939 PF11159.8 EAX65159.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65159.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3781 PF12636.7 EAX65161.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX65162.1 - 3.1e-07 30.1 2.8 4.9e-07 29.4 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65162.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX65162.1 - 0.055 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX65162.1 - 0.06 13.1 0.1 0.28 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2805 PF10985.8 EAX65162.1 - 0.12 12.8 3.3 0.52 10.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX65162.1 - 0.43 10.8 8.5 5.8 7.1 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX65163.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF2939 PF11159.8 EAX65164.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX65165.1 - 0.025 14.5 0.1 0.054 13.4 0.0 1.5 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF257 PF03192.13 EAX65166.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65166.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Mito_fiss_reg PF05308.11 EAX65167.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65167.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX65169.1 - 0.027 14.9 1.1 0.027 14.9 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX65170.1 - 0.007 16.1 0.8 0.026 14.3 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4116) Pox_D5 PF03288.16 EAX65171.1 - 2.3e-05 24.8 2.1 0.00011 22.6 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65171.1 - 0.064 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF2939 PF11159.8 EAX65172.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65172.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX65172.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX65172.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX65173.1 - 0.011 15.7 0.2 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF1043 PF06295.12 EAX65176.1 - 0.062 13.3 0.2 0.08 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX65177.1 - 0.0053 17.2 0.8 0.0061 17.0 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65177.1 - 1.2 9.2 6.9 1.3 9.0 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EpuA PF11772.8 EAX65178.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TcdB_toxin_midN PF12256.8 EAX65178.1 - 0.027 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF3839 PF12943.7 EAX65179.1 - 2.3e-155 515.2 14.1 2.7e-155 514.9 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX65179.1 - 0.11 12.9 2.1 0.21 12.0 0.4 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX65179.1 - 1.2 9.6 9.0 2.2 8.8 1.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX65180.1 - 2.1e-64 216.6 1.8 2.4e-64 216.4 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DnaT PF17948.1 EAX65180.1 - 0.5 10.1 2.7 0.84 9.4 2.7 1.3 1 0 0 1 1 1 0 DnaT DNA-binding domain JMY PF15871.5 EAX65182.1 - 0.0058 16.0 0.6 0.0078 15.6 0.6 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX65182.1 - 0.15 12.1 0.7 0.27 11.3 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX65182.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain PapD_N PF00345.20 EAX65184.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65184.1 - 0.033 14.2 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX65185.1 - 0.017 15.5 0.5 0.021 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65185.1 - 1.4 8.9 5.8 1.5 8.8 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX65185.1 - 1.5 7.8 2.7 1.6 7.7 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein O-antigen_lig PF13425.6 EAX65186.1 - 1.6 7.4 3.5 2.1 7.0 3.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BRO1 PF03097.18 EAX65189.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX65189.1 - 5.5 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX65190.1 - 8.2e-09 35.3 0.0 9.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65190.1 - 0.00027 20.7 0.0 0.00039 20.1 0.0 1.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX65190.1 - 0.09 12.7 0.9 0.13 12.1 0.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4107 PF13389.6 EAX65191.1 - 0.068 13.3 0.3 0.099 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) FAS_N PF17828.1 EAX65192.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65193.1 - 0.022 15.2 0.5 0.028 14.8 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65193.1 - 2.7 8.0 5.6 2.9 7.9 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3781 PF12636.7 EAX65194.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TPR_MLP1_2 PF07926.12 EAX65195.1 - 0.063 13.3 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Vasculin PF15337.6 EAX65195.1 - 0.09 13.6 0.6 0.13 13.1 0.3 1.5 1 1 0 1 1 1 0 Vascular protein family Vasculin-like 1 PaRep2a PF07903.11 EAX65195.1 - 0.096 12.5 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX65195.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX65196.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX65196.1 - 0.071 13.6 0.8 0.49 10.9 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB DUF2408 PF10303.9 EAX65196.1 - 0.072 13.7 0.6 0.085 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX65196.1 - 0.084 12.4 0.3 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 SLOG cluster2 PRD PF00874.20 EAX65196.1 - 0.099 12.9 1.0 0.19 12.0 0.2 1.9 2 0 0 2 2 2 0 PRD domain GalP_UDP_transf PF01087.22 EAX65196.1 - 0.54 10.7 2.9 1.1 9.6 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF1493 PF07377.12 EAX65198.1 - 0.0041 17.6 0.9 0.0083 16.6 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) FLYWCH PF04500.16 EAX65200.1 - 0.041 14.0 3.6 0.074 13.2 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX65200.1 - 0.051 14.3 0.1 0.12 13.1 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DNA_pol_B_2 PF03175.13 EAX65201.1 - 9.7e-12 44.5 0.6 1.9e-11 43.6 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65201.1 - 0.039 13.3 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4107 PF13389.6 EAX65202.1 - 6.5e-31 107.7 2.1 7.5e-31 107.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ACP_PD PF04336.12 EAX65205.1 - 0.031 14.7 0.0 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF3839 PF12943.7 EAX65206.1 - 4.3e-134 445.5 10.4 4.9e-134 445.3 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX65206.1 - 0.52 10.8 7.2 4 8.0 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAS_N PF17828.1 EAX65207.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX65207.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Trypan_PARP PF05887.11 EAX65210.1 - 0.24 11.4 7.1 0.27 11.2 7.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AbfS_sensor PF18225.1 EAX65214.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain PTR PF12789.7 EAX65215.1 - 0.029 14.4 2.0 0.029 14.4 2.0 3.8 5 1 0 5 5 5 0 Phage tail repeat like BRO1 PF03097.18 EAX65215.1 - 0.053 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX65215.1 - 0.12 12.0 7.0 0.47 10.0 7.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX65215.1 - 1.7 9.2 5.2 27 5.4 0.1 3.3 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX65215.1 - 4.2 7.8 16.2 4 7.9 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF2689 PF10894.8 EAX65218.1 - 0.037 13.8 0.2 24 4.8 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2689) SVS_QK PF10578.9 EAX65218.1 - 7.5 7.4 15.5 2 9.2 0.2 4.3 4 1 0 4 4 4 0 Seminal vesicle protein repeat DUF4108 PF13390.6 EAX65220.1 - 6.1e-36 123.5 1.8 7e-36 123.3 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65220.1 - 0.13 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein BRO1 PF03097.18 EAX65221.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX65221.1 - 5.6 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX65222.1 - 5.3e-05 22.8 3.0 8.5e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65222.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65222.1 - 0.019 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX65222.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 TMP PF05017.14 EAX65223.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65224.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX65225.1 - 3.2e-20 72.4 3.9 5.3e-20 71.7 3.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX65227.1 - 0.0042 17.5 0.7 0.0048 17.3 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65227.1 - 1.8 8.6 7.2 1.9 8.5 7.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX65228.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Pox_D5 PF03288.16 EAX65231.1 - 5.9e-06 26.7 3.0 3.8e-05 24.1 3.0 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like YpsA PF06908.11 EAX65231.1 - 0.022 14.8 0.3 0.029 14.3 0.3 1.1 1 0 0 1 1 1 0 YspA SLOG family RFX_DNA_binding PF02257.15 EAX65231.1 - 0.025 15.2 0.1 0.047 14.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65231.1 - 0.049 13.6 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX65232.1 - 0.00024 20.7 0.3 0.00029 20.4 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein RhoGEF PF00621.20 EAX65232.1 - 0.031 14.5 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 RhoGEF domain Zot PF05707.12 EAX65232.1 - 0.053 13.2 0.0 0.053 13.2 0.0 1.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Tho2 PF11262.8 EAX65233.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX65233.1 - 0.079 13.6 0.9 0.13 13.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX65233.1 - 0.38 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family TMP PF05017.14 EAX65234.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat VirE PF05272.11 EAX65235.1 - 1e-05 25.4 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX65235.1 - 0.058 13.8 0.4 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 RNA helicase Gly-zipper_Omp PF13488.6 EAX65236.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX65236.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX65236.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2939 PF11159.8 EAX65241.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65241.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX65241.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX65241.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX65242.1 - 3.3e-21 75.7 4.9 4.2e-21 75.4 4.9 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65242.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX65243.1 - 9.4e-25 86.5 28.3 3.7e-24 84.6 5.0 4.9 3 2 0 3 3 3 2 Phage tail repeat like DDR PF08841.10 EAX65245.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX65245.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2939 PF11159.8 EAX65247.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65247.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX65249.1 - 1.5e-33 116.2 1.5 1.8e-33 116.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_4 PF13637.6 EAX65250.1 - 3.1e-08 34.0 0.0 3.1e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX65250.1 - 7e-07 29.4 0.1 0.038 14.4 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX65250.1 - 4.5e-05 24.0 0.1 7.4e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX65250.1 - 0.00016 21.8 0.0 0.19 12.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX65250.1 - 0.00051 20.3 0.0 0.00062 20.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4108 PF13390.6 EAX65251.1 - 1.6e-59 200.0 8.9 1.8e-59 199.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) NMT PF01233.19 EAX65252.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DEAD PF00270.29 EAX65254.1 - 6e-05 22.9 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX65254.1 - 0.00015 21.8 1.1 0.00029 20.9 1.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX65254.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65254.1 - 0.004 17.0 0.2 0.0077 16.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65254.1 - 0.031 14.6 0.0 0.041 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65254.1 - 0.05 13.2 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX65254.1 - 0.054 12.9 0.1 0.081 12.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX65254.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein APG12 PF04110.13 EAX65254.1 - 0.62 10.5 3.7 0.33 11.4 0.7 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Amidase02_C PF12123.8 EAX65255.1 - 0.0075 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1493 PF07377.12 EAX65256.1 - 0.016 15.6 0.4 0.031 14.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65256.1 - 0.38 10.8 3.7 6.1 7.0 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX65258.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65259.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX65261.1 - 0.069 13.0 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX65262.1 - 0.03 14.3 8.3 0.047 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65262.1 - 3.7 8.0 5.1 5.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX65263.1 - 2.7e-126 420.0 7.6 3e-126 419.8 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX65263.1 - 0.21 11.9 1.1 0.43 10.9 1.1 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX65263.1 - 0.71 10.2 2.7 4.4 7.6 0.0 2.8 2 1 1 3 3 3 0 Rx N-terminal domain PapD_N PF00345.20 EAX65265.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65265.1 - 0.078 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX65265.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pox_A32 PF04665.12 EAX65266.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX65266.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65266.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65266.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65266.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65266.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65266.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65266.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65266.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65266.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65266.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX65266.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX65266.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX65268.1 - 0.025 15.1 3.0 11 7.2 0.2 3.0 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65269.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65270.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat YmaF PF12788.7 EAX65272.1 - 0.24 11.9 2.1 13 6.4 0.2 2.2 1 1 0 2 2 2 0 YmaF family HNH_3 PF13392.6 EAX65273.1 - 3.8e-08 33.0 0.3 6.8e-08 32.2 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 EAX65276.1 - 3e-05 24.1 0.1 4.3e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65276.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65276.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX65276.1 - 0.0019 18.5 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65276.1 - 0.0039 17.5 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65276.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX65276.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX65276.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX65276.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX65277.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein ACP_PD PF04336.12 EAX65278.1 - 0.17 12.3 0.5 1.2 9.6 0.0 2.5 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase PRA-PH PF01503.17 EAX65279.1 - 0.39 11.2 2.3 3 8.4 2.8 2.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase KilA-N PF04383.13 EAX65280.1 - 1.9e-34 117.9 0.2 1.9e-34 117.9 0.2 1.7 2 1 1 3 3 3 1 KilA-N domain Parathyroid PF01279.17 EAX65280.1 - 0.019 15.6 0.0 0.047 14.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX65280.1 - 0.39 10.7 4.4 1.3 9.1 0.5 2.2 2 0 0 2 2 2 0 Tumour suppressor protein MULE PF10551.9 EAX65281.1 - 8.2e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain TFCD_C PF12612.8 EAX65282.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal TMP PF05017.14 EAX65283.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat HC2 PF07382.11 EAX65285.1 - 1.3e-07 31.9 12.4 1.5e-07 31.7 12.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX65285.1 - 4.2e-05 23.6 0.5 5.1e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Aurora-A_bind PF09041.10 EAX65285.1 - 0.96 9.6 8.7 2.3e+02 1.9 8.7 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX65285.1 - 1.8 8.6 5.1 71 3.5 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) FliD_N PF02465.18 EAX65286.1 - 0.56 10.9 5.0 0.9 10.3 5.0 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX65286.1 - 1.7 7.4 3.5 2.1 7.0 3.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4106 PF13388.6 EAX65287.1 - 1.3e-116 390.3 13.5 1.3e-116 390.3 13.5 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX65287.1 - 0.19 10.3 3.8 0.27 9.8 3.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3452 PF11934.8 EAX65287.1 - 1.3 8.6 4.9 0.23 11.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX65287.1 - 2 8.4 4.5 0.73 9.8 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4678 PF15727.5 EAX65287.1 - 4.7 6.4 10.3 0.19 10.9 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) PSP PF04046.16 EAX65288.1 - 0.055 13.3 0.7 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 PSP Mid2 PF04478.12 EAX65289.1 - 0.00083 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX65289.1 - 0.0011 18.7 1.9 0.0019 17.9 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX65289.1 - 0.0015 18.6 3.3 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 EAX65289.1 - 0.0081 16.1 5.3 0.014 15.3 0.1 2.4 2 0 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.20 EAX65289.1 - 0.0098 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX65289.1 - 0.014 15.6 5.7 0.016 15.4 0.0 2.5 2 1 0 2 2 2 0 Glycophorin A Orf78 PF06024.12 EAX65289.1 - 0.027 14.7 3.5 0.15 12.3 0.2 2.8 3 1 0 3 3 3 0 Orf78 (ac78) ECSCR PF15820.5 EAX65289.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PsbW PF07123.12 EAX65289.1 - 0.095 12.7 1.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) EphA2_TM PF14575.6 EAX65289.1 - 0.1 13.5 0.1 0.34 11.8 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 EAX65289.1 - 0.1 12.0 3.5 0.18 11.2 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3827 PF12877.7 EAX65289.1 - 0.15 10.4 0.0 0.15 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) MMM1 PF10296.9 EAX65289.1 - 0.18 10.8 1.9 0.29 10.1 0.1 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 PTP_tm PF18861.1 EAX65289.1 - 0.18 11.8 1.1 0.51 10.3 0.5 2.0 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Cortexin PF11057.8 EAX65289.1 - 0.19 11.6 0.1 0.73 9.7 0.0 2.0 3 0 0 3 3 3 0 Cortexin of kidney DUF4330 PF14221.6 EAX65289.1 - 4.3 7.5 6.7 28 4.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) LRV PF01816.17 EAX65290.1 - 0.95 10.0 3.0 72 4.1 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat variant Pox_A9 PF04835.12 EAX65290.1 - 0.99 9.6 5.4 3.7 7.8 0.1 3.5 3 0 0 3 3 3 0 A9 protein conserved region PH_TFIIH PF08567.11 EAX65290.1 - 1.7 9.1 5.3 1.6e+02 2.7 0.0 4.9 4 1 2 6 6 6 0 TFIIH p62 subunit, N-terminal domain HemY_N PF07219.13 EAX65290.1 - 3.8 7.7 4.6 44 4.3 0.0 3.1 3 0 0 3 3 3 0 HemY protein N-terminus Presenilin PF01080.17 EAX65292.1 - 0.35 9.6 0.9 0.42 9.3 0.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4107 PF13389.6 EAX65293.1 - 4.5e-73 244.8 4.5 5.4e-73 244.5 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX65293.1 - 0.18 10.2 0.8 0.26 9.7 0.8 1.2 1 0 0 1 1 1 0 Lipoxygenase Mito_fiss_reg PF05308.11 EAX65294.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65294.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_22 PF13401.6 EAX65298.1 - 3.7e-05 24.0 0.1 0.00024 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65298.1 - 6.7e-05 23.0 2.8 0.00011 22.3 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX65298.1 - 8.4e-05 22.4 0.3 0.27 11.0 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX65298.1 - 0.00037 20.3 0.0 0.0005 19.9 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65298.1 - 0.00072 19.4 0.7 0.0026 17.6 0.8 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65298.1 - 0.0081 16.5 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65298.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65298.1 - 0.067 13.6 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX65298.1 - 0.072 12.8 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX65298.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65298.1 - 0.094 13.0 4.3 2.5 8.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX65298.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX65298.1 - 0.96 9.9 4.5 0.44 11.0 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX65300.1 - 5.8e-63 211.1 5.8 6.5e-63 210.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX65301.1 - 1.3e-10 41.5 2.8 1.8e-10 41.1 1.2 2.0 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX65301.1 - 0.01 15.9 0.9 0.043 13.9 0.9 2.1 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma WRKY PF03106.15 EAX65301.1 - 0.04 14.2 2.0 0.072 13.3 0.2 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain FLYWCH PF04500.16 EAX65301.1 - 0.099 12.8 0.9 0.21 11.7 0.9 1.6 1 0 0 1 1 1 0 FLYWCH zinc finger domain Ly49 PF08391.10 EAX65302.1 - 0.27 11.6 2.0 0.31 11.4 2.0 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX65302.1 - 0.28 11.1 3.6 0.5 10.3 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65303.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) YmaF PF12788.7 EAX65305.1 - 0.046 14.3 1.7 6 7.5 0.1 2.0 1 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX65305.1 - 9.2 6.7 9.5 8.1 6.9 0.9 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX65306.1 - 0.035 14.6 0.6 0.065 13.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65306.1 - 0.73 9.9 3.7 13 6.0 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX65307.1 - 0.074 13.7 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65308.1 - 0.085 12.7 1.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX65309.1 - 4e-151 501.2 15.4 4.9e-151 500.9 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX65309.1 - 0.071 13.6 1.9 0.22 11.9 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX65309.1 - 0.3 11.6 5.5 1.9 9.0 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX65310.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat ACP_PD PF04336.12 EAX65312.1 - 0.14 12.6 0.6 1 9.8 0.0 2.5 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase PTR PF12789.7 EAX65315.1 - 2.3e-05 24.4 0.6 2.3e-05 24.4 0.6 3.2 2 1 0 2 2 2 1 Phage tail repeat like DUF445 PF04286.12 EAX65315.1 - 0.0096 15.8 4.6 0.014 15.2 4.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX65315.1 - 0.041 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX65315.1 - 0.11 12.2 0.6 1.4 8.6 0.1 2.3 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 MeaB PF03308.16 EAX65315.1 - 0.12 11.3 0.6 0.2 10.6 0.6 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX65315.1 - 0.14 12.6 2.1 0.41 11.1 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) ATP-cone PF03477.16 EAX65315.1 - 0.22 12.1 1.5 0.77 10.4 0.3 2.5 1 1 1 2 2 2 0 ATP cone domain DUF2120 PF09893.9 EAX65315.1 - 0.43 10.7 3.7 1.5 8.9 0.4 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4795 PF16043.5 EAX65315.1 - 1.1 8.8 14.7 0.52 9.9 7.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PKcGMP_CC PF16808.5 EAX65315.1 - 3.7 7.5 7.2 2.3 8.1 0.3 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4795 PF16043.5 EAX65317.1 - 0.01 15.5 0.3 0.013 15.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF2897 PF11446.8 EAX65318.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pex14_N PF04695.13 EAX65321.1 - 3.2 8.4 12.2 3.8 8.1 12.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.11 EAX65322.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65322.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ResIII PF04851.15 EAX65323.1 - 5.8e-05 23.2 2.6 0.00011 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX65323.1 - 5.9e-05 23.4 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX65323.1 - 0.00043 20.1 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65323.1 - 0.00076 19.3 0.8 0.0022 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65323.1 - 0.0075 16.6 0.0 0.0096 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65323.1 - 0.0095 15.7 0.2 0.23 11.2 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX65323.1 - 0.05 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65323.1 - 0.074 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65323.1 - 0.1 13.0 0.1 0.38 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65323.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65323.1 - 0.24 11.7 4.5 5.3 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Ribosomal_L28e PF01778.17 EAX65325.1 - 0.0083 16.9 4.7 0.0096 16.7 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2939 PF11159.8 EAX65325.1 - 0.021 15.2 1.3 0.029 14.8 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) FAA_hydrolase_N PF09298.11 EAX65325.1 - 0.027 14.7 1.9 0.038 14.2 1.9 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF2863 PF11062.8 EAX65325.1 - 0.088 11.2 1.9 0.1 11.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Y2_Tnp PF04986.13 EAX65325.1 - 0.23 11.5 3.0 0.29 11.2 3.0 1.1 1 0 0 1 1 1 0 Putative transposase DUF1378 PF07125.11 EAX65325.1 - 0.84 9.8 2.1 0.85 9.8 0.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1378) Tctex-1 PF03645.13 EAX65325.1 - 3 8.1 5.5 2.3 8.5 0.5 2.0 1 1 1 2 2 2 0 Tctex-1 family TMIE PF16038.5 EAX65325.1 - 6.2 6.7 10.4 1.9 8.4 2.6 2.2 2 0 0 2 2 2 0 TMIE protein FAS_N PF17828.1 EAX65326.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta MULE PF10551.9 EAX65328.1 - 2.1e-10 40.9 0.2 4.8e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX65328.1 - 0.0049 16.6 0.4 0.029 14.1 0.2 1.9 1 1 1 2 2 2 1 Transposase Transposase_mut PF00872.18 EAX65328.1 - 0.0052 15.7 0.2 0.0078 15.1 0.2 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX65328.1 - 0.055 13.4 0.3 0.09 12.7 0.3 1.3 1 0 0 1 1 1 0 Vta1 like DUF3298 PF11738.8 EAX65328.1 - 0.12 13.4 0.3 0.84 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3298) Amidase02_C PF12123.8 EAX65329.1 - 0.0038 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX65330.1 - 4.9e-10 38.9 1.7 8.1e-10 38.2 1.0 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX65331.1 - 1e-11 44.4 0.9 2.1e-11 43.4 0.9 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65331.1 - 0.043 13.1 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Pox_A32 PF04665.12 EAX65332.1 - 2.3e-05 24.0 2.9 2.7e-05 23.7 2.6 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65332.1 - 0.0023 17.9 0.2 0.0053 16.8 0.2 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65332.1 - 0.0073 15.9 0.3 0.015 14.9 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX65332.1 - 0.034 14.4 1.1 0.087 13.1 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX65332.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 FAS_N PF17828.1 EAX65333.1 - 0.017 15.1 0.2 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX65334.1 - 5.3e-05 22.8 3.0 8.5e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65334.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65334.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX65334.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Imm70 PF15601.6 EAX65335.1 - 0.76 9.3 8.5 22 4.6 0.4 3.8 1 1 3 4 4 4 0 Immunity protein 70 DUF1493 PF07377.12 EAX65336.1 - 0.0099 16.3 0.2 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65336.1 - 0.29 11.2 4.0 4.7 7.3 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PapD_N PF00345.20 EAX65338.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TFCD_C PF12612.8 EAX65339.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal ResIII PF04851.15 EAX65340.1 - 1.9e-05 24.8 1.1 3.4e-05 23.9 1.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65340.1 - 0.00028 20.7 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65340.1 - 0.00041 20.6 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65340.1 - 0.0013 18.5 0.1 0.002 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65340.1 - 0.0063 16.8 0.0 0.0078 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65340.1 - 0.033 13.6 0.1 0.042 13.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX65340.1 - 0.059 13.0 0.4 0.094 12.4 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX65340.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX65340.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX65340.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX65340.1 - 0.49 10.8 2.8 0.43 11.0 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 T5orf172 PF10544.9 EAX65341.1 - 2.1e-06 28.2 0.1 4.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX65341.1 - 0.0032 17.0 0.7 0.064 12.8 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX65341.1 - 0.019 14.8 0.1 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain DUF563 PF04577.14 EAX65342.1 - 2.6e-31 109.4 0.6 3.4e-31 109.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ResIII PF04851.15 EAX65344.1 - 4.5e-05 23.5 2.5 7.7e-05 22.8 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65344.1 - 0.0003 20.6 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65344.1 - 0.00032 21.0 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65344.1 - 0.0013 18.6 0.8 0.0031 17.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65344.1 - 0.0083 16.5 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65344.1 - 0.041 13.3 0.0 0.098 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX65344.1 - 0.046 13.5 0.0 0.075 12.8 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein SWI2_SNF2 PF18766.1 EAX65344.1 - 0.047 13.4 0.5 0.08 12.6 0.2 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF4588 PF15251.6 EAX65344.1 - 0.052 13.3 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX65344.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX65344.1 - 0.31 11.5 4.3 0.13 12.7 1.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1827 PF08860.10 EAX65344.1 - 0.54 10.5 4.1 11 6.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) LRR_5 PF13306.6 EAX65347.1 - 2.7e-48 163.2 11.7 2.3e-26 92.3 4.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX65347.1 - 3.4e-06 26.7 0.0 0.71 9.7 0.0 5.1 3 1 4 7 7 7 3 Leucine rich repeat Nab1 PF04902.12 EAX65350.1 - 0.0089 16.5 1.7 0.011 16.2 1.7 1.1 1 0 0 1 1 1 1 Conserved region in Nab1 DUF3839 PF12943.7 EAX65351.1 - 1.1e-117 391.8 7.3 1.2e-117 391.6 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX65351.1 - 0.062 12.8 1.0 0.086 12.3 0.6 1.4 1 1 0 1 1 1 0 Z1 domain JMY PF15871.5 EAX65352.1 - 0.0081 15.5 0.4 0.011 15.0 0.4 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein VirE PF05272.11 EAX65353.1 - 1.2e-05 25.2 0.1 1.9e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX65353.1 - 0.047 12.8 1.7 0.18 10.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX65353.1 - 0.081 13.3 0.3 0.24 11.8 0.1 2.0 1 1 0 2 2 2 0 RNA helicase LpoB PF13036.6 EAX65355.1 - 0.054 13.4 0.7 0.079 12.9 0.6 1.3 1 1 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Tctex-1 PF03645.13 EAX65355.1 - 0.11 12.8 0.5 0.15 12.3 0.5 1.3 1 0 0 1 1 1 0 Tctex-1 family HTH_32 PF13565.6 EAX65355.1 - 0.31 11.7 4.6 0.44 11.2 4.6 1.2 1 0 0 1 1 1 0 Homeodomain-like domain TSP_NTD PF17804.1 EAX65355.1 - 0.33 11.2 5.8 0.44 10.8 5.8 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Membralin PF09746.9 EAX65355.1 - 2 7.4 3.4 1.9 7.4 3.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 EAX65355.1 - 3.4 7.7 4.1 3.7 7.5 4.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 EAX65355.1 - 4.9 7.2 6.1 5.3 7.0 6.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Exonuc_VII_S PF02609.16 EAX65356.1 - 0.078 13.1 0.0 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit ACP_PD PF04336.12 EAX65356.1 - 0.081 13.4 0.1 0.72 10.3 0.0 2.1 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase Ank_2 PF12796.7 EAX65357.1 - 8.1e-32 109.7 3.0 4.3e-11 43.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX65357.1 - 3.3e-27 94.5 4.3 8.4e-08 32.6 0.4 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX65357.1 - 2.1e-23 82.1 0.0 9e-07 29.1 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65357.1 - 2.7e-20 70.3 1.1 4.9e-05 23.4 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EAX65357.1 - 1.5e-17 63.1 1.0 0.00022 21.6 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 EAX65357.1 - 0.0014 18.6 1.1 1.3 9.1 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) AAA_22 PF13401.6 EAX65358.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65358.1 - 7.5e-05 22.8 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65358.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65358.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65358.1 - 0.0021 17.8 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65358.1 - 0.0078 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65358.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65358.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65358.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65358.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65358.1 - 0.24 11.7 4.5 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX65360.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF257 PF03192.13 EAX65362.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65362.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX65363.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX65364.1 - 1.1e-52 178.9 3.0 1.3e-52 178.7 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX65364.1 - 0.021 14.5 0.3 0.027 14.1 0.3 1.1 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit DUF2547 PF10818.8 EAX65364.1 - 0.035 15.0 0.4 5 8.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Glu-tRNAGln PF02686.15 EAX65364.1 - 0.16 12.3 1.5 0.43 10.9 1.5 1.8 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit FAS_N PF17828.1 EAX65365.1 - 0.011 15.7 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF1493 PF07377.12 EAX65366.1 - 0.035 14.6 0.7 0.071 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX65368.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX65369.1 - 0.026 15.0 0.6 0.046 14.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX65370.1 - 2.5e-117 390.6 6.7 2.9e-117 390.4 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX65370.1 - 0.039 13.5 0.7 0.054 13.0 0.5 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX65370.1 - 0.092 13.4 2.5 0.5 11.0 0.1 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX65370.1 - 2 8.8 4.3 14 6.1 0.1 2.9 2 1 1 3 3 3 0 Rx N-terminal domain DUF4108 PF13390.6 EAX65371.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX65372.1 - 0.59 10.1 3.2 1.1 9.2 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX65372.1 - 0.84 10.0 3.4 1 9.8 3.4 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4337 PF14235.6 EAX65372.1 - 6.1 6.9 4.8 7.4 6.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_22 PF13401.6 EAX65374.1 - 0.015 15.6 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAX65374.1 - 0.017 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX65374.1 - 0.037 13.5 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX65374.1 - 0.047 13.7 0.1 0.078 13.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX65374.1 - 0.062 13.6 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX65375.1 - 1.2e-156 519.4 15.6 1.4e-156 519.1 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX65375.1 - 0.11 13.0 0.4 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX65375.1 - 0.17 11.8 1.1 0.73 9.7 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX65375.1 - 1.4 9.4 7.4 2 8.9 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX65376.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65376.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX65377.1 - 5e-18 65.2 4.5 6.3e-18 64.9 4.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX65378.1 - 8.1e-23 81.0 4.9 1e-22 80.7 4.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4107 PF13389.6 EAX65379.1 - 7e-46 156.3 0.8 7.8e-46 156.2 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX65379.1 - 0.057 13.8 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF1731 PF08338.11 EAX65382.1 - 0.14 12.0 0.1 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1731) DUF846 PF05832.12 EAX65383.1 - 0.035 14.1 0.1 0.059 13.4 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF2939 PF11159.8 EAX65385.1 - 0.025 15.0 0.5 0.031 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65385.1 - 1.3 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65385.1 - 1.4 8.9 5.5 1.5 8.8 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Trypan_PARP PF05887.11 EAX65387.1 - 0.054 13.5 13.6 0.057 13.4 13.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX65388.1 - 5.3e-36 122.5 21.7 3.3e-33 113.5 13.7 4.6 2 2 3 5 5 5 2 Phage tail repeat like DUF3839 PF12943.7 EAX65389.1 - 7.2e-119 395.6 10.5 9.1e-119 395.3 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX65389.1 - 0.037 14.5 0.3 0.055 13.9 0.3 1.3 1 0 0 1 1 1 0 Fez1 KELK PF15796.5 EAX65389.1 - 0.047 14.1 3.2 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX65390.1 - 4.6e-151 501.1 13.6 5.3e-151 500.8 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX65390.1 - 0.083 13.2 1.5 10 6.5 0.0 3.0 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX65390.1 - 0.17 12.3 4.2 1.3 9.5 0.2 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX65391.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65391.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX65391.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX65391.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX65392.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX65396.1 - 5.6e-09 35.4 1.2 9.9e-09 34.6 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65396.1 - 0.09 12.8 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX65396.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 AAA_22 PF13401.6 EAX65397.1 - 6.2e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65397.1 - 0.0001 22.4 3.7 0.00019 21.5 3.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65397.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65397.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65397.1 - 0.0027 17.4 0.3 0.28 10.9 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65397.1 - 0.0077 16.6 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65397.1 - 0.047 13.1 0.1 0.07 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65397.1 - 0.074 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65397.1 - 0.092 13.2 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65397.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain BAR_2 PF10455.9 EAX65398.1 - 0.043 13.0 1.0 0.05 12.7 1.0 1.0 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3839 PF12943.7 EAX65399.1 - 5.4e-151 500.8 16.2 6.7e-151 500.5 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX65399.1 - 0.14 12.0 1.3 0.47 10.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX65399.1 - 0.14 12.6 6.5 0.66 10.5 0.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2897 PF11446.8 EAX65402.1 - 0.12 12.3 3.6 0.21 11.5 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX65403.1 - 6.6e-05 23.3 0.1 0.00019 21.8 0.1 1.8 1 0 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX65403.1 - 0.017 14.2 1.2 0.024 13.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Pox_D5 PF03288.16 EAX65404.1 - 0.00087 19.7 2.7 0.0053 17.2 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX65404.1 - 0.035 13.2 1.1 0.047 12.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4106 PF13388.6 EAX65405.1 - 3.7e-48 164.8 6.1 3.7e-48 164.8 6.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) WYL_3 PF18488.1 EAX65405.1 - 3.2 8.2 14.8 8 6.9 0.4 4.1 3 1 1 4 4 4 0 WYL domain LMBR1 PF04791.16 EAX65405.1 - 9.1 5.0 14.6 11 4.8 14.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMP PF05017.14 EAX65406.1 - 0.034 14.7 2.6 11 7.2 0.2 2.7 2 0 0 2 2 2 0 TMP repeat DUF1493 PF07377.12 EAX65407.1 - 0.048 14.1 0.2 0.089 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX65409.1 - 1.7e-64 216.1 6.7 1.8e-64 215.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX65409.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide MetW PF07021.12 EAX65410.1 - 0.092 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF3839 PF12943.7 EAX65411.1 - 9.9e-148 490.1 16.2 1.2e-147 489.9 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX65411.1 - 0.07 13.6 0.3 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX65411.1 - 0.19 12.2 5.9 4.7 7.8 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX65411.1 - 0.23 12.0 6.7 0.13 12.8 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Amidase02_C PF12123.8 EAX65412.1 - 0.01 15.5 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX65413.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX65416.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65417.1 - 0.028 14.8 0.4 0.038 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX65417.1 - 2.6 8.7 6.3 6.1 7.5 6.3 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Pox_A32 PF04665.12 EAX65418.1 - 4e-06 26.5 0.2 8.7e-06 25.4 0.1 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF4795 PF16043.5 EAX65419.1 - 0.0047 16.5 2.2 0.011 15.4 2.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PTR PF12789.7 EAX65419.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.3 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX65419.1 - 0.082 13.1 12.8 3.2 8.2 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX65419.1 - 4.4 7.9 7.2 7.2 7.2 2.1 3.1 3 1 0 3 3 3 0 YmaF family Pox_A32 PF04665.12 EAX65420.1 - 0.00017 21.2 2.6 0.00017 21.2 2.6 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65420.1 - 0.0044 17.0 0.1 0.0094 16.0 0.1 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65420.1 - 0.0075 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX65420.1 - 0.043 14.1 1.0 0.11 12.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX65420.1 - 0.061 12.6 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 AAA_22 PF13401.6 EAX65421.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65421.1 - 7.5e-05 22.8 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65421.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65421.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65421.1 - 0.0021 17.8 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65421.1 - 0.0078 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65421.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65421.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65421.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65421.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65421.1 - 0.24 11.7 4.5 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) NMT PF01233.19 EAX65422.1 - 0.083 12.7 0.4 0.1 12.4 0.4 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF3839 PF12943.7 EAX65424.1 - 7.8e-79 264.5 9.6 1e-78 264.1 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FAS_N PF17828.1 EAX65425.1 - 0.0057 16.7 0.2 0.0076 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta SPECT1 PF18680.1 EAX65428.1 - 0.085 12.5 0.4 0.1 12.3 0.4 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 T5orf172 PF10544.9 EAX65429.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX65430.1 - 7e-09 35.5 0.0 7.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65430.1 - 0.00028 20.6 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF4107 PF13389.6 EAX65431.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX65433.1 - 0.041 14.4 0.5 0.1 13.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX65436.1 - 1.8e-22 79.9 4.5 2.3e-22 79.5 4.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65436.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) EpuA PF11772.8 EAX65437.1 - 0.028 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX65438.1 - 1.2e-16 60.5 1.3 1.2e-16 60.5 1.3 3.6 3 1 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX65438.1 - 0.0056 16.3 2.1 0.0094 15.6 1.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX65439.1 - 2.6e-11 43.1 0.2 2.6e-11 43.1 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65439.1 - 0.01 15.2 0.3 0.014 14.7 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX65440.1 - 4.4e-152 504.4 14.0 5.1e-152 504.2 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX65440.1 - 0.088 13.1 2.8 0.3 11.4 1.1 2.5 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX65440.1 - 3.1 8.3 6.7 6.1 7.4 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX65442.1 - 2.8e-07 30.3 0.2 3.1e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX65448.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein Imm70 PF15601.6 EAX65450.1 - 0.2 11.2 3.7 5.7 6.5 0.3 2.8 1 1 2 3 3 3 0 Immunity protein 70 DNA_pol_B_2 PF03175.13 EAX65451.1 - 1.9e-08 33.6 1.5 3.6e-08 32.7 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX65451.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 AAA_22 PF13401.6 EAX65452.1 - 6.3e-05 23.3 0.1 0.00037 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65452.1 - 0.00056 19.8 0.5 0.0016 18.3 0.5 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65452.1 - 0.00072 19.6 2.4 0.0014 18.7 2.4 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65452.1 - 0.0047 16.7 0.0 0.0065 16.2 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EAX65452.1 - 0.0065 16.2 0.3 0.2 11.4 0.0 2.5 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65452.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65452.1 - 0.046 13.2 0.1 0.073 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65452.1 - 0.069 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) TPK_catalytic PF04263.16 EAX65452.1 - 0.098 12.7 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA PF00004.29 EAX65452.1 - 0.13 12.7 0.0 0.49 10.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65452.1 - 0.14 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65452.1 - 0.16 12.2 4.0 5.2 7.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX65452.1 - 0.78 10.2 3.9 0.39 11.2 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_pol_B_2 PF03175.13 EAX65456.1 - 2.1e-24 86.3 6.0 3.7e-24 85.4 6.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX65458.1 - 1.1e-11 44.3 0.8 2.1e-11 43.4 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65458.1 - 0.0094 15.3 0.2 0.014 14.7 0.2 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF4108 PF13390.6 EAX65459.1 - 1.6e-59 200.0 8.1 1.7e-59 199.8 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Transposase_mut PF00872.18 EAX65461.1 - 0.0024 16.8 0.3 0.0036 16.2 0.3 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX65461.1 - 0.034 14.1 0.3 0.055 13.4 0.3 1.3 1 0 0 1 1 1 0 Vta1 like DUF4107 PF13389.6 EAX65462.1 - 6.3e-74 247.5 4.5 7.4e-74 247.3 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX65462.1 - 0.3 9.4 1.1 0.4 9.0 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase Pox_A32 PF04665.12 EAX65463.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65463.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX65463.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX65463.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX65463.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX65463.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX65463.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PSP PF04046.16 EAX65464.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PAXIP1_C PF15364.6 EAX65465.1 - 0.062 13.6 1.7 0.086 13.1 1.7 1.4 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Pox_A32 PF04665.12 EAX65467.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein PSP PF04046.16 EAX65468.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX65469.1 - 1.1e-06 28.3 3.4 1.2e-06 28.2 1.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX65469.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65469.1 - 4.6e-05 23.2 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65469.1 - 0.00011 22.3 2.9 0.00022 21.3 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65469.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65469.1 - 0.0016 18.3 0.8 0.0038 17.0 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65469.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65469.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65469.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65469.1 - 0.084 13.3 0.1 0.69 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65469.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65469.1 - 0.38 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX65470.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2939 PF11159.8 EAX65473.1 - 0.022 15.2 0.7 0.029 14.8 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65473.1 - 2.1 7.3 4.8 2.3 7.2 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65473.1 - 4 7.5 8.4 4.3 7.3 8.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX65474.1 - 3.1e-63 212.0 5.9 3.4e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX65475.1 - 5.6e-05 23.6 2.7 0.00039 20.8 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65475.1 - 0.071 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF2939 PF11159.8 EAX65476.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65476.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 IstB_IS21 PF01695.17 EAX65477.1 - 2.8e-05 23.9 0.2 0.32 10.7 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX65477.1 - 6.1e-05 23.3 0.1 0.0004 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65477.1 - 0.00016 21.8 4.0 0.0002 21.4 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX65477.1 - 0.00025 20.6 2.5 0.00025 20.6 2.5 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein DEAD PF00270.29 EAX65477.1 - 0.00059 19.6 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65477.1 - 0.0021 17.9 0.5 0.0047 16.8 0.3 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65477.1 - 0.0071 16.0 2.5 0.017 14.7 0.2 2.3 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65477.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX65477.1 - 0.069 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX65477.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX65477.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65477.1 - 0.15 12.5 0.7 0.72 10.3 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX65477.1 - 1.1 9.9 8.7 0.24 12.1 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX65477.1 - 1.3 9.3 5.1 11 6.4 0.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX65479.1 - 2.7e-19 69.4 3.3 4.5e-19 68.7 3.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65479.1 - 0.069 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein TMP PF05017.14 EAX65481.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4116 PF13475.6 EAX65482.1 - 0.005 16.5 0.5 0.018 14.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) PapD_N PF00345.20 EAX65483.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX65484.1 - 1.2e-16 60.7 2.5 1.5e-16 60.4 2.5 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TMP PF05017.14 EAX65485.1 - 0.037 14.6 4.0 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65486.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX65487.1 - 0.041 13.9 8.7 0.064 13.2 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX65488.1 - 1.6e-07 31.0 0.8 9.8e-07 28.5 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX65488.1 - 0.032 13.9 0.1 1.2 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX65488.1 - 0.097 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX65488.1 - 0.19 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMP PF05017.14 EAX65489.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX65492.1 - 2.6e-09 36.5 1.0 4.5e-09 35.7 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65492.1 - 0.082 12.9 0.0 0.7 9.9 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor GPS2_interact PF15784.5 EAX65493.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX65493.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX65494.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65494.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AAA_22 PF13401.6 EAX65496.1 - 4.1e-05 23.9 0.1 0.00027 21.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65496.1 - 0.0001 22.4 3.1 0.00019 21.5 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65496.1 - 0.0005 19.9 0.0 0.00072 19.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65496.1 - 0.001 18.9 0.8 0.003 17.4 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65496.1 - 0.0021 17.8 0.2 0.35 10.6 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65496.1 - 0.009 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65496.1 - 0.056 12.9 0.1 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65496.1 - 0.089 13.2 0.0 0.43 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65496.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65496.1 - 0.18 12.0 4.2 4.7 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX65498.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX65500.1 - 5e-152 507.0 18.0 5e-152 507.0 18.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KilA-N PF04383.13 EAX65501.1 - 1.7e-31 108.3 0.7 4.1e-31 107.1 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX65501.1 - 0.0027 18.3 0.1 0.0081 16.8 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family YmaF PF12788.7 EAX65502.1 - 0.1 13.1 1.7 4.4 7.9 0.1 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX65502.1 - 0.56 10.5 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX65503.1 - 1.6e-05 24.9 0.4 1.6e-05 24.9 0.4 3.2 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX65503.1 - 0.016 14.5 0.6 0.024 13.9 0.6 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF445 PF04286.12 EAX65503.1 - 0.02 14.7 0.3 0.025 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX65503.1 - 0.034 14.6 0.0 0.088 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX65503.1 - 0.38 10.3 3.9 1.4 8.5 3.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAX65505.1 - 0.13 12.9 7.2 6.3 7.9 0.8 3.2 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX65505.1 - 6.6 6.7 8.4 7.2 6.6 8.4 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_D5 PF03288.16 EAX65506.1 - 3.8e-05 24.1 2.3 0.00023 21.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX65506.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Mito_fiss_reg PF05308.11 EAX65508.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65508.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RNPHF PF08080.12 EAX65511.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger DUF1493 PF07377.12 EAX65513.1 - 0.017 15.6 0.9 0.033 14.7 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX65514.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) PSP PF04046.16 EAX65516.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX65517.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65517.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX65517.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX65517.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX65518.1 - 3.6e-07 30.7 0.3 7.2e-07 29.7 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX65519.1 - 1.5e-35 121.4 0.1 3.1e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX65520.1 - 8.3e-155 513.3 12.7 1.1e-154 512.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX65520.1 - 0.059 13.8 1.8 0.62 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Rx_N PF18052.1 EAX65520.1 - 0.074 13.3 0.2 1.6 9.0 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX65520.1 - 0.076 12.9 0.9 0.27 11.1 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX65520.1 - 0.083 13.3 0.4 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX65520.1 - 1.4 9.4 6.0 2.1 8.9 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glyco_hydro_30 PF02055.16 EAX65521.1 - 5.4e-09 35.5 0.0 7.5e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydr_30_2 PF14587.6 EAX65521.1 - 0.033 13.8 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 PapD_N PF00345.20 EAX65523.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65523.1 - 0.027 14.5 0.4 0.036 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX65523.1 - 0.099 12.6 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PTR PF12789.7 EAX65524.1 - 0.00011 22.1 0.4 0.00011 22.1 0.4 3.4 4 1 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX65524.1 - 0.0027 17.6 4.0 0.0032 17.3 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1048 PF06304.11 EAX65524.1 - 0.012 16.0 0.6 0.038 14.4 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF3417 PF11897.8 EAX65524.1 - 0.012 16.1 0.3 0.098 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) FliD_N PF02465.18 EAX65525.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX65525.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ResIII PF04851.15 EAX65527.1 - 6.4e-05 23.0 2.7 0.00011 22.2 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX65527.1 - 9.4e-05 22.7 0.0 0.00042 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX65527.1 - 0.00044 20.1 0.0 0.00061 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65527.1 - 0.0012 18.7 0.9 0.0035 17.2 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65527.1 - 0.002 17.9 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65527.1 - 0.0087 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65527.1 - 0.049 13.1 0.1 0.073 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65527.1 - 0.062 13.1 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65527.1 - 0.095 13.1 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65527.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65527.1 - 0.22 11.8 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX65528.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX65529.1 - 3.3e-08 32.8 1.2 6.7e-08 31.8 0.7 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX65529.1 - 0.071 11.8 1.8 1 8.0 1.8 2.3 1 1 0 1 1 1 0 DNA polymerase family B PTR PF12789.7 EAX65530.1 - 1.4e-08 34.6 1.0 1.4e-08 34.6 1.0 3.9 4 2 1 5 5 5 2 Phage tail repeat like BRO1 PF03097.18 EAX65530.1 - 0.049 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF5017 PF16409.5 EAX65530.1 - 0.069 12.6 1.5 1.5 8.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) YmaF PF12788.7 EAX65530.1 - 0.17 12.4 3.7 23 5.6 0.0 3.4 4 0 0 4 4 4 0 YmaF family Transposase_24 PF03004.14 EAX65530.1 - 0.22 11.6 4.2 1.2 9.2 3.7 2.2 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF4795 PF16043.5 EAX65530.1 - 0.58 9.7 11.6 0.28 10.8 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX65530.1 - 3.7 8.0 16.9 4.3 7.8 2.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF2939 PF11159.8 EAX65531.1 - 0.01 16.3 0.5 0.012 16.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65531.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX65532.1 - 9.1e-17 60.9 1.9 9.1e-17 60.9 1.9 3.7 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX65532.1 - 0.0032 17.1 1.1 0.0041 16.8 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX65533.1 - 1.8e-153 508.9 11.9 2.3e-153 508.6 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX65537.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65538.1 - 0.065 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX65539.1 - 6.6e-73 243.3 11.7 7.5e-73 243.2 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF5623 PF18536.1 EAX65540.1 - 0.047 14.0 0.1 0.059 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Ank_4 PF13637.6 EAX65542.1 - 1.1e-28 99.2 4.4 2.8e-08 34.2 0.4 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX65542.1 - 2.3e-28 98.6 2.0 5.7e-11 42.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX65542.1 - 6.4e-24 83.7 0.0 8e-07 29.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65542.1 - 7.2e-21 72.0 0.4 4.5e-05 23.5 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EAX65542.1 - 2e-18 65.9 0.8 0.0002 21.7 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 EAX65542.1 - 0.0016 18.4 0.8 1.2 9.2 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) DUF3839 PF12943.7 EAX65543.1 - 2.7e-40 138.4 5.1 3.8e-40 137.9 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX65543.1 - 0.062 13.4 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF2408 PF10303.9 EAX65543.1 - 0.071 13.7 0.5 0.082 13.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX65543.1 - 0.085 13.2 1.1 0.16 12.3 0.2 1.9 2 0 0 2 2 2 0 PRD domain LD_cluster2 PF18163.1 EAX65543.1 - 0.097 12.2 0.2 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 SLOG cluster2 BRE1 PF08647.11 EAX65543.1 - 0.2 11.8 5.0 1.3 9.1 2.2 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Mito_fiss_reg PF05308.11 EAX65545.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65545.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAR1 PF03101.15 EAX65546.1 - 0.027 15.1 0.1 0.056 14.1 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF4107 PF13389.6 EAX65547.1 - 1.5e-37 129.2 0.9 1.8e-37 129.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Mito_fiss_reg PF05308.11 EAX65549.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65549.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAS_N PF17828.1 EAX65550.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65551.1 - 0.034 14.5 0.2 0.034 14.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) AAA_22 PF13401.6 EAX65552.1 - 6.3e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65552.1 - 6.8e-05 22.9 2.7 0.00012 22.2 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65552.1 - 0.0004 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65552.1 - 0.00079 19.3 0.9 0.0022 17.8 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65552.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65552.1 - 0.029 14.1 0.2 1.1 9.0 0.0 2.5 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX65552.1 - 0.042 13.3 0.1 0.056 12.9 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65552.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65552.1 - 0.1 13.0 0.0 0.36 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65552.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX65552.1 - 0.2 11.3 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PTR PF12789.7 EAX65554.1 - 9.6e-06 25.6 8.0 1.4e-05 25.0 0.6 3.0 3 0 0 3 3 3 1 Phage tail repeat like Kinetochor_Ybp2 PF08568.10 EAX65554.1 - 0.044 12.3 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin YmaF PF12788.7 EAX65554.1 - 0.13 12.8 2.4 1 10.0 0.9 2.5 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX65554.1 - 3.9 7.9 9.7 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX65555.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX65555.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2939 PF11159.8 EAX65556.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65556.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX65556.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX65556.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX65559.1 - 5.1e-80 268.4 10.4 6.6e-80 268.1 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX65559.1 - 0.28 11.0 1.8 1 9.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MciZ PF13072.6 EAX65559.1 - 3.1 7.7 5.0 1.1e+02 2.8 0.0 3.7 2 1 2 4 4 4 0 Mother cell inhibitor of FtsZ FAS_N PF17828.1 EAX65560.1 - 0.0088 16.1 0.1 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX65562.1 - 0.13 12.9 8.0 6.4 7.9 0.8 3.4 3 1 0 3 3 3 0 TMP repeat GPS2_interact PF15784.5 EAX65563.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX65563.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX65564.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DNA_pol_B_2 PF03175.13 EAX65565.1 - 2.9e-10 39.6 7.7 3.8e-10 39.2 3.6 2.0 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX65565.1 - 0.091 12.3 0.7 0.19 11.2 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX65565.1 - 0.097 12.9 0.1 0.19 11.9 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PhaP_Bmeg PF09602.10 EAX65565.1 - 0.12 12.3 0.1 1.3 8.9 0.1 2.2 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TMP PF05017.14 EAX65567.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Parathyroid PF01279.17 EAX65568.1 - 0.038 14.6 0.1 0.08 13.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family PSP PF04046.16 EAX65569.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX65571.1 - 1.2e-22 80.4 4.2 2.5e-22 79.4 4.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65571.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Trypan_PARP PF05887.11 EAX65572.1 - 0.072 13.1 9.4 0.12 12.4 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WRKY PF03106.15 EAX65573.1 - 0.0078 16.4 0.1 0.0078 16.4 0.1 2.1 2 1 0 2 2 2 1 WRKY DNA -binding domain VIGSSK PF14773.6 EAX65573.1 - 0.35 11.0 1.8 20 5.4 0.2 2.3 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal Trypan_PARP PF05887.11 EAX65577.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX65578.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX65578.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4108 PF13390.6 EAX65579.1 - 2.5e-43 147.4 4.2 2.8e-43 147.3 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65579.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX65583.1 - 4.7e-05 23.5 2.7 9e-05 22.5 2.7 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65583.1 - 0.00031 20.6 0.0 0.00043 20.1 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65583.1 - 0.00034 20.9 0.0 0.00058 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65583.1 - 0.00076 19.3 1.0 0.0022 17.8 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65583.1 - 0.0062 16.9 0.0 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65583.1 - 0.038 13.5 0.1 0.082 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65583.1 - 0.077 13.2 4.7 1.4 9.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) IstB_IS21 PF01695.17 EAX65583.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX65583.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX65583.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX65584.1 - 3.6e-05 24.1 0.1 0.00023 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65584.1 - 7.4e-05 22.5 0.3 0.27 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65584.1 - 7.7e-05 22.8 2.8 0.00013 22.0 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65584.1 - 0.00037 20.3 0.1 0.00051 19.9 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65584.1 - 0.00092 19.1 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65584.1 - 0.0084 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65584.1 - 0.055 12.9 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65584.1 - 0.066 13.0 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX65584.1 - 0.071 13.5 0.1 0.41 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65584.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65584.1 - 0.2 11.9 4.3 6.2 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX65585.1 - 8e-07 28.8 2.4 8e-07 28.8 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX65585.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65585.1 - 3.9e-05 23.4 0.3 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65585.1 - 0.00021 21.4 3.8 0.00049 20.1 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65585.1 - 0.00059 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX65585.1 - 0.0018 18.0 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX65585.1 - 0.0019 18.1 0.9 0.0039 17.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65585.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65585.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65585.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65585.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65585.1 - 0.39 11.0 4.1 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX65586.1 - 0.015 15.8 0.3 0.025 15.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65586.1 - 0.36 10.9 3.7 8.7 6.5 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF2294 PF10057.9 EAX65587.1 - 0.056 13.6 3.3 5 7.3 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF1935 PF09149.10 EAX65587.1 - 0.39 11.1 5.3 0.74 10.2 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1935) PS-DH PF14765.6 EAX65587.1 - 0.58 9.3 5.7 0.89 8.7 5.7 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase FAM219A PF15260.6 EAX65587.1 - 0.64 10.4 5.6 9.2 6.6 1.0 2.7 2 1 1 3 3 3 0 Protein family FAM219A MlaD PF02470.20 EAX65587.1 - 0.73 10.2 4.9 4.9 7.5 0.8 2.8 1 1 2 3 3 3 0 MlaD protein DUF3332 PF11810.8 EAX65587.1 - 2.1 8.0 6.0 3.7 7.2 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DNA_pol_B_2 PF03175.13 EAX65588.1 - 4.9e-09 35.6 1.0 8.8e-09 34.7 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65588.1 - 0.087 12.8 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX65588.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2939 PF11159.8 EAX65589.1 - 0.02 15.3 0.5 0.028 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65589.1 - 1.2 8.1 3.2 1.2 8.1 3.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65589.1 - 3.1 7.8 6.7 3.4 7.7 6.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2939 PF11159.8 EAX65591.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) KilA-N PF04383.13 EAX65592.1 - 3.9e-33 113.6 0.5 9.8e-33 112.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX65592.1 - 0.0074 16.9 0.9 0.017 15.8 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX65592.1 - 0.86 9.9 6.8 1.5 9.1 0.3 2.3 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pox_A32 PF04665.12 EAX65593.1 - 3.3e-08 33.3 0.8 1.5e-06 27.9 0.0 2.4 1 1 0 2 2 2 1 Poxvirus A32 protein zf-BED PF02892.15 EAX65593.1 - 0.017 15.1 0.2 0.044 13.8 0.2 1.6 1 0 0 1 1 1 0 BED zinc finger AAA_33 PF13671.6 EAX65593.1 - 0.035 14.2 0.0 0.059 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX65593.1 - 0.04 14.2 0.1 0.066 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EAX65593.1 - 0.092 12.4 0.1 2 8.0 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) SNF2_N PF00176.23 EAX65593.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1493 PF07377.12 EAX65594.1 - 0.025 15.1 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65594.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF688 PF05097.12 EAX65596.1 - 0.065 12.4 0.7 0.067 12.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Radial_spoke PF04712.12 EAX65596.1 - 0.24 10.3 5.1 0.24 10.3 5.1 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein PSP PF04046.16 EAX65597.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP RGS12_us1 PF16613.5 EAX65598.1 - 0.31 11.3 3.4 0.52 10.6 3.4 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 PapD_N PF00345.20 EAX65600.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65600.1 - 0.071 13.1 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX65600.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Ank_2 PF12796.7 EAX65601.1 - 1.1e-06 29.2 0.0 1.2e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX65601.1 - 1.9e-05 25.1 0.0 2.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX65601.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65601.1 - 0.0051 17.2 0.0 0.058 14.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX65601.1 - 0.078 13.5 0.0 5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DUF3839 PF12943.7 EAX65602.1 - 1.8e-145 482.8 13.7 2.3e-145 482.4 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX65602.1 - 0.48 10.7 3.8 1 9.7 0.1 2.9 3 0 0 3 3 3 0 PRD domain KELK PF15796.5 EAX65602.1 - 0.55 10.7 5.0 1.5 9.4 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX65604.1 - 2.7e-12 46.3 0.3 5.4e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65604.1 - 0.0076 15.6 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein VirK PF06903.12 EAX65605.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 2 0 0 2 2 2 0 VirK protein DUF4378 PF14309.6 EAX65607.1 - 0.03 14.7 0.0 0.15 12.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) DUF1493 PF07377.12 EAX65608.1 - 0.043 14.3 0.5 0.081 13.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65608.1 - 0.49 10.5 3.4 9.9 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX65609.1 - 3.7e-153 507.9 12.5 4.6e-153 507.6 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX65609.1 - 0.11 13.5 1.6 0.29 12.1 0.3 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Glu-tRNAGln PF02686.15 EAX65609.1 - 0.61 10.4 2.5 0.68 10.3 0.2 2.3 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF1493 PF07377.12 EAX65610.1 - 0.017 15.6 0.8 0.032 14.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) MULE PF10551.9 EAX65611.1 - 1.1e-11 45.0 0.1 2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX65611.1 - 0.061 13.5 3.6 0.11 12.6 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX65611.1 - 0.078 13.7 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF1493 PF07377.12 EAX65612.1 - 0.028 14.9 0.8 0.061 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2897 PF11446.8 EAX65613.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65614.1 - 2e-42 144.5 2.9 2.2e-42 144.4 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65614.1 - 0.14 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_D5 PF03288.16 EAX65615.1 - 2.4e-05 24.7 2.1 0.00011 22.6 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX65615.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX65615.1 - 0.062 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF2897 PF11446.8 EAX65616.1 - 1.1 9.2 3.0 1.7 8.6 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX65617.1 - 4.9e-05 23.4 2.3 9.2e-05 22.5 2.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65617.1 - 0.0003 20.6 0.0 0.00037 20.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65617.1 - 0.00039 20.7 0.0 0.00068 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65617.1 - 0.00089 19.1 1.3 0.003 17.4 1.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65617.1 - 0.0066 16.8 0.0 0.009 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65617.1 - 0.027 14.2 0.3 0.17 11.6 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX65617.1 - 0.038 13.4 0.1 0.059 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX65617.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65617.1 - 0.16 12.2 4.4 4.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX65617.1 - 0.82 10.1 4.3 0.33 11.4 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Trypan_PARP PF05887.11 EAX65618.1 - 0.039 13.9 8.7 0.052 13.5 8.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX65619.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX65622.1 - 0.092 12.4 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Trypan_PARP PF05887.11 EAX65623.1 - 0.12 12.3 4.3 0.18 11.7 4.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX65624.1 - 0.01 15.7 0.3 0.02 14.7 0.3 1.7 1 1 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX65624.1 - 0.035 13.4 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX65624.1 - 0.042 13.4 0.3 0.054 13.0 0.3 1.1 1 0 0 1 1 1 0 Legume lectin domain Amidase02_C PF12123.8 EAX65625.1 - 0.0065 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Synaptobrevin PF00957.21 EAX65627.1 - 0.0032 17.2 0.3 0.0041 16.9 0.3 1.1 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.9 EAX65627.1 - 0.08 12.8 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PTR PF12789.7 EAX65628.1 - 7.1e-09 35.6 3.4 7.1e-09 35.6 3.4 5.3 4 3 1 5 5 5 2 Phage tail repeat like ATR13 PF16829.5 EAX65628.1 - 0.1 13.0 5.1 0.13 12.6 2.6 2.4 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector DUF4795 PF16043.5 EAX65628.1 - 0.11 12.1 21.9 0.12 12.0 2.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX65629.1 - 4.2e-34 116.8 0.2 4.2e-34 116.8 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX65629.1 - 0.021 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) PTR PF12789.7 EAX65631.1 - 8.5e-39 131.4 25.0 1.3e-32 111.7 14.6 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX65631.1 - 0.077 12.7 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) SAS4 PF15460.6 EAX65631.1 - 0.41 10.8 5.9 11 6.1 0.1 3.2 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 Pox_D5 PF03288.16 EAX65632.1 - 7.8e-06 26.3 2.9 4.5e-05 23.8 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65632.1 - 0.02 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65632.1 - 0.06 13.3 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX65633.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX65634.1 - 0.028 14.3 2.1 0.038 13.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2897 PF11446.8 EAX65635.1 - 1.2 9.1 6.7 1.5 8.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RNA_polI_A34 PF08208.11 EAX65635.1 - 3.7 7.6 18.4 3.8 7.5 18.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.10 EAX65635.1 - 7.5 6.6 7.9 7.6 6.6 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4108 PF13390.6 EAX65636.1 - 3.5e-53 179.4 8.1 3.9e-53 179.2 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX65637.1 - 9.4e-06 26.0 0.6 1.3e-05 25.6 0.6 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65637.1 - 0.014 16.0 0.1 0.019 15.6 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65637.1 - 0.019 14.9 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX65638.1 - 1.5e-156 519.0 12.6 1.8e-156 518.7 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX65638.1 - 0.2 12.1 7.1 1.8 9.1 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX65638.1 - 1.3 9.3 4.3 7.9 6.8 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX65638.1 - 1.5 9.4 4.9 1.4 9.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_D5 PF03288.16 EAX65639.1 - 8.4e-05 23.0 2.2 0.00055 20.4 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like KilA-N PF04383.13 EAX65640.1 - 4.7e-43 145.6 0.0 6.7e-43 145.1 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Pox_D5 PF03288.16 EAX65641.1 - 1.1e-05 25.8 3.4 6.2e-05 23.4 3.4 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65641.1 - 0.016 15.8 0.1 0.029 15.0 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65641.1 - 0.028 14.4 0.2 0.044 13.8 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX65642.1 - 1.7e-61 206.3 8.2 1.9e-61 206.2 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX65643.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX65643.1 - 0.045 13.8 0.2 0.064 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2400 PF09674.10 EAX65643.1 - 0.068 13.1 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX65644.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX65644.1 - 0.022 14.8 0.2 0.028 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2400 PF09674.10 EAX65644.1 - 0.031 14.3 0.4 0.041 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX65648.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65648.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX65648.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX65648.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX65649.1 - 1.7e-80 270.0 10.7 2.2e-80 269.6 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX65649.1 - 0.14 12.0 1.0 0.59 10.0 0.1 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2486 PF10667.9 EAX65650.1 - 0.14 12.3 28.9 0.091 13.0 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Trypan_PARP PF05887.11 EAX65652.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX65652.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FliD_N PF02465.18 EAX65654.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX65654.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2897 PF11446.8 EAX65655.1 - 0.5 10.3 3.0 0.63 10.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65656.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX65657.1 - 2.1e-05 24.9 3.3 0.00017 22.0 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX65657.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DNA_pol_B_2 PF03175.13 EAX65658.1 - 8.1e-23 81.0 4.0 1e-22 80.7 4.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65658.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PapD_N PF00345.20 EAX65660.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX65660.1 - 0.1 12.6 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX65662.1 - 1.2e-40 137.8 0.1 2.4e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX65662.1 - 0.037 14.2 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX65663.1 - 9.9e-07 29.3 0.1 1.9e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX65664.1 - 0.041 14.4 0.9 0.077 13.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) IstB_IS21 PF01695.17 EAX65665.1 - 2e-05 24.4 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX65665.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX65665.1 - 3.3e-05 23.5 1.9 3.3e-05 23.5 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX65665.1 - 0.00031 20.8 4.5 0.00057 19.9 4.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65665.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65665.1 - 0.0025 17.6 1.5 0.0049 16.7 0.6 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65665.1 - 0.003 17.2 2.7 0.0096 15.6 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65665.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX65665.1 - 0.063 13.3 0.7 0.99 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX65665.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65665.1 - 0.075 13.5 0.1 0.72 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX65665.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65665.1 - 0.6 10.4 5.0 8.4 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX65665.1 - 3.2 8.5 10.7 0.28 11.9 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 MGC-24 PF05283.11 EAX65666.1 - 4.7 7.7 7.2 6.9 7.1 7.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ResIII PF04851.15 EAX65667.1 - 1.7e-05 24.9 2.7 3.2e-05 24.0 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65667.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65667.1 - 0.00026 21.3 0.1 0.0014 18.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65667.1 - 0.0011 18.8 0.3 0.2 11.3 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_11 PF13086.6 EAX65667.1 - 0.0034 17.2 0.9 0.0098 15.7 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65667.1 - 0.017 15.5 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65667.1 - 0.026 14.8 3.6 0.97 9.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) SWI2_SNF2 PF18766.1 EAX65667.1 - 0.046 13.4 0.3 0.064 12.9 0.2 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA PF00004.29 EAX65667.1 - 0.1 13.0 0.1 0.49 10.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65667.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PSP PF04046.16 EAX65668.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65669.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX65672.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX65672.1 - 0.077 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX65672.1 - 0.084 12.1 0.0 0.094 12.0 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX65672.1 - 0.23 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX65672.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX65674.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX65679.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX65680.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1340 PF07067.11 EAX65681.1 - 0.16 11.3 0.6 0.18 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) PTR PF12789.7 EAX65683.1 - 0.1 12.7 5.6 0.52 10.4 0.1 2.7 3 0 0 3 3 3 0 Phage tail repeat like Phage_fiber PF03335.13 EAX65683.1 - 0.17 12.1 4.8 1.8 9.0 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Peptidase_S64 PF08192.11 EAX65684.1 - 0.013 14.0 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 UCH PF00443.29 EAX65684.1 - 0.048 13.1 1.0 1 8.8 1.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Fungal_lectin_2 PF18647.1 EAX65684.1 - 0.13 12.8 0.5 0.28 11.7 0.2 1.8 1 1 1 2 2 2 0 Alpha-galactosyl-binding fungal lectin KilA-N PF04383.13 EAX65685.1 - 1.7e-42 143.8 0.5 7.1e-42 141.8 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX65685.1 - 0.062 13.9 0.1 0.16 12.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX65687.1 - 9.3e-07 29.3 0.3 1.8e-06 28.5 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX65691.1 - 0.012 15.6 0.2 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3447 PF11929.8 EAX65693.1 - 1.7e-37 127.2 6.3 1.7e-37 127.2 6.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX65693.1 - 0.003 18.1 0.1 0.01 16.4 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) PTR PF12789.7 EAX65694.1 - 1.5e-27 95.4 11.6 1.5e-27 95.4 11.6 3.7 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX65694.1 - 0.079 12.7 1.0 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Phage_fiber PF03335.13 EAX65694.1 - 4.2 7.8 15.9 3.6 8.0 1.1 3.6 4 0 0 4 4 4 0 Phage tail fibre repeat DUF1672 PF07901.11 EAX65694.1 - 5 6.4 14.0 0.38 10.0 9.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) DUF257 PF03192.13 EAX65695.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65695.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Dehydrin PF00257.19 EAX65696.1 - 0.03 14.9 1.2 0.034 14.7 1.2 1.2 1 0 0 1 1 1 0 Dehydrin Paf1 PF03985.13 EAX65696.1 - 0.71 8.8 7.4 0.9 8.5 7.4 1.0 1 0 0 1 1 1 0 Paf1 DUF1493 PF07377.12 EAX65698.1 - 0.014 15.8 0.8 0.028 14.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX65699.1 - 2.7e-69 232.4 2.0 3.2e-69 232.2 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDE_1 PF03184.19 EAX65702.1 - 1.1e-16 61.0 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Gly-zipper_Omp PF13488.6 EAX65704.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX65704.1 - 0.23 11.8 4.5 0.37 11.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX65704.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif FAS_N PF17828.1 EAX65706.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Phage_fiber PF03335.13 EAX65707.1 - 0.76 10.1 4.6 9.1 6.8 0.2 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX65708.1 - 5e-10 38.8 1.9 7.9e-10 38.2 1.3 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX65708.1 - 0.062 12.0 1.7 1 8.0 1.7 2.3 1 1 0 1 1 1 0 DNA polymerase family B VirE PF05272.11 EAX65709.1 - 0.0071 16.1 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX65709.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX65709.1 - 0.11 11.4 0.2 9.6 5.0 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Amidase02_C PF12123.8 EAX65710.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX65710.1 - 0.18 11.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX65711.1 - 3.7e-09 36.0 0.1 7.8e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65711.1 - 0.027 13.8 0.3 0.039 13.3 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX65711.1 - 0.14 12.2 0.3 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DUF2897 PF11446.8 EAX65712.1 - 0.23 11.4 3.7 0.29 11.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65713.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX65714.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65714.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65714.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3781 PF12636.7 EAX65715.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX65716.1 - 4.4e-05 23.1 3.9 7.8e-05 22.2 3.9 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65716.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65716.1 - 0.0099 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX65716.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX65716.1 - 0.067 13.5 2.1 0.15 12.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Swi5 PF07061.11 EAX65718.1 - 0.16 12.1 0.7 0.64 10.2 0.7 2.0 1 1 0 1 1 1 0 Swi5 PSP PF04046.16 EAX65719.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX65720.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65721.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65721.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDR PF08841.10 EAX65723.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX65723.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX65726.1 - 5.9e-121 402.4 11.1 7.4e-121 402.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX65726.1 - 0.0079 16.6 1.9 1.8 9.0 0.0 3.3 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX65728.1 - 4.6e-09 35.7 1.3 6.7e-09 35.1 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65728.1 - 0.081 12.9 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor TPR_MLP1_2 PF07926.12 EAX65729.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX65729.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX65729.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX65730.1 - 8.7e-10 38.0 1.1 1.4e-09 37.4 0.7 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4108 PF13390.6 EAX65731.1 - 1.3e-62 210.0 5.8 1.4e-62 209.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65731.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PSP PF04046.16 EAX65733.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65734.1 - 0.037 14.6 4.1 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX65735.1 - 4.2e-07 29.7 3.0 4.2e-07 29.7 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX65735.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65735.1 - 0.00011 22.2 2.7 0.00026 21.0 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX65735.1 - 0.00023 20.9 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX65735.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65735.1 - 0.0011 18.8 0.6 0.0019 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65735.1 - 0.0015 18.2 0.7 0.0084 15.8 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65735.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX65735.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX65735.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65735.1 - 0.091 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4108 PF13390.6 EAX65737.1 - 6.7e-43 146.0 2.9 7.4e-43 145.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65737.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DNA_pol_B_2 PF03175.13 EAX65740.1 - 6.4e-24 84.6 4.9 1e-23 84.0 4.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX65741.1 - 0.028 14.9 0.5 0.053 14.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX65742.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX65744.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2939 PF11159.8 EAX65745.1 - 0.012 16.0 0.4 0.015 15.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65745.1 - 0.94 8.4 2.7 0.93 8.5 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65745.1 - 1.7 8.7 5.7 1.8 8.6 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HD_2 PF12917.7 EAX65746.1 - 0.098 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF1493 PF07377.12 EAX65747.1 - 0.025 15.1 0.4 0.048 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65747.1 - 0.3 11.1 3.6 5.8 7.0 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein ABC2_membrane_3 PF12698.7 EAX65748.1 - 4.8e-05 22.6 1.2 6.1e-05 22.3 1.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4366 PF14283.6 EAX65748.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 EAX65748.1 - 0.0039 17.1 1.3 0.0053 16.7 1.3 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAX65748.1 - 0.0041 16.6 0.2 0.0046 16.4 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) BatD PF13584.6 EAX65748.1 - 0.0087 14.9 0.1 0.0094 14.8 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance RIFIN PF02009.16 EAX65748.1 - 0.013 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX65748.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX65748.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OppC_N PF12911.7 EAX65748.1 - 0.026 14.5 0.9 0.051 13.5 0.9 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FeoB_associated PF12669.7 EAX65748.1 - 0.037 14.4 2.1 0.061 13.7 2.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CD34_antigen PF06365.12 EAX65748.1 - 0.04 13.5 0.2 0.056 13.0 0.2 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 EAX65748.1 - 0.098 12.7 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gemini_mov PF01708.16 EAX65748.1 - 1.7 8.4 4.1 3.5 7.5 1.5 2.0 1 1 1 2 2 2 0 Geminivirus putative movement protein DUF4108 PF13390.6 EAX65750.1 - 7.3e-36 123.2 1.2 7.9e-36 123.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX65750.1 - 0.099 11.7 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF3839 PF12943.7 EAX65751.1 - 7.8e-157 519.9 13.5 8.9e-157 519.8 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX65751.1 - 0.21 12.0 6.4 3.7 8.1 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX65752.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65752.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HNH_3 PF13392.6 EAX65753.1 - 2.7e-07 30.2 0.1 4.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF2897 PF11446.8 EAX65754.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_11 PF13086.6 EAX65755.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX65755.1 - 0.0047 17.2 0.0 0.0075 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65755.1 - 0.015 14.7 0.1 0.018 14.5 0.1 1.2 1 1 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX65755.1 - 0.019 15.0 0.1 0.027 14.5 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX65755.1 - 0.024 15.0 0.1 0.036 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65755.1 - 0.039 13.5 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX65755.1 - 0.068 12.9 0.0 0.076 12.7 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein PSP PF04046.16 EAX65756.1 - 0.071 13.0 0.9 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65757.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX65757.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX65759.1 - 0.0099 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX65760.1 - 9.8e-81 270.8 10.6 1.3e-80 270.4 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ACP_PD PF04336.12 EAX65761.1 - 0.024 15.0 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF2939 PF11159.8 EAX65762.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65762.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PRA-PH PF01503.17 EAX65764.1 - 0.32 11.5 2.8 0.51 10.8 2.8 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase HNH_3 PF13392.6 EAX65765.1 - 1.6e-07 31.0 0.3 2.8e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Mito_fiss_reg PF05308.11 EAX65766.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65766.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_A32 PF04665.12 EAX65768.1 - 5.4e-07 29.3 0.1 1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein HTH_17 PF12728.7 EAX65769.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Noggin PF05806.12 EAX65770.1 - 0.22 11.4 0.9 0.33 10.8 0.9 1.2 1 0 0 1 1 1 0 Noggin TPR_MLP1_2 PF07926.12 EAX65771.1 - 0.049 13.7 0.2 0.056 13.5 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX65771.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX65771.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Amidase02_C PF12123.8 EAX65774.1 - 0.071 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX65776.1 - 5.1e-73 246.7 9.4 5.1e-73 246.7 9.4 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) VP4_2 PF08935.10 EAX65776.1 - 0.071 13.7 0.7 0.22 12.1 0.7 1.8 1 0 0 1 1 1 0 Viral protein VP4 subunit KAR PF15222.6 EAX65776.1 - 0.18 12.1 1.9 0.36 11.1 0.2 2.2 2 0 0 2 2 2 0 Kidney androgen-regulated Phage_fiber_2 PF03406.13 EAX65776.1 - 9.5 5.9 9.3 2.5 7.7 2.6 3.1 3 0 0 3 3 3 0 Phage tail fibre repeat DUF5106 PF17127.4 EAX65777.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF1493 PF07377.12 EAX65778.1 - 0.075 13.5 1.2 0.095 13.2 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX65778.1 - 0.16 12.1 2.8 5.9 7.0 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX65780.1 - 1.3e-07 31.4 0.1 1.5e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF2939 PF11159.8 EAX65782.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65782.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX65783.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65784.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Mito_fiss_reg PF05308.11 EAX65785.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX65785.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX65786.1 - 8.4e-71 238.2 10.7 1.2e-70 237.8 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX65786.1 - 0.058 13.9 0.1 0.074 13.5 0.1 1.1 1 0 0 1 1 1 0 Fez1 NTP_transf_6 PF06042.11 EAX65786.1 - 0.2 11.5 1.6 0.49 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase AAA_22 PF13401.6 EAX65788.1 - 2.4e-05 24.6 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65788.1 - 3.1e-05 23.8 0.3 0.28 10.9 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX65788.1 - 0.00011 22.2 3.2 0.00024 21.2 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX65788.1 - 0.00031 20.3 2.2 0.00031 20.3 2.2 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX65788.1 - 0.00045 20.0 0.1 0.00087 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65788.1 - 0.0011 18.8 0.6 0.0028 17.5 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65788.1 - 0.0013 18.4 0.5 0.01 15.5 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65788.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX65788.1 - 0.051 13.2 0.0 0.17 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65788.1 - 0.061 13.8 0.1 0.54 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX65788.1 - 0.062 12.8 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX65788.1 - 0.076 12.4 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX65788.1 - 0.34 11.2 4.3 8.5 6.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX65789.1 - 6e-41 140.3 0.9 7.4e-41 140.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX65789.1 - 0.063 13.7 0.6 0.078 13.3 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta T5orf172 PF10544.9 EAX65791.1 - 1.1e-06 29.1 0.1 2.8e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX65791.1 - 0.0046 16.8 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX65792.1 - 1.4e-09 37.9 9.0 4.2e-05 23.5 0.6 3.3 3 0 0 3 3 3 2 Phage tail repeat like NPV_P10 PF05531.12 EAX65792.1 - 0.19 12.2 0.9 26 5.4 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YmaF PF12788.7 EAX65792.1 - 0.73 10.4 7.3 1.3 9.6 1.2 3.1 2 2 0 2 2 2 0 YmaF family TMP PF05017.14 EAX65795.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65796.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX65798.1 - 2.9e-05 23.6 3.1 3.5e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65798.1 - 0.0027 17.7 1.2 0.0072 16.3 0.2 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX65798.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX65798.1 - 0.066 13.5 2.1 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX65800.1 - 4.9e-07 29.5 2.3 7.2e-07 28.9 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65800.1 - 0.045 13.4 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX65800.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX65800.1 - 0.11 12.2 0.1 0.49 10.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX65800.1 - 0.23 11.5 2.2 1.6 8.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX65801.1 - 3.9e-07 29.8 0.1 9e-07 28.6 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein PBAN PF05874.11 EAX65801.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) DNA_pol_B_2 PF03175.13 EAX65802.1 - 2.2e-10 40.0 3.2 6.9e-10 38.4 3.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65802.1 - 0.073 13.1 0.0 0.73 9.9 0.0 2.5 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX65802.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 VirK PF06903.12 EAX65803.1 - 0.032 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 VirK protein DNA_pol_B_2 PF03175.13 EAX65804.1 - 5.1e-19 68.5 4.2 1.7e-18 66.8 4.2 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65804.1 - 0.084 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX65805.1 - 1.8e-12 46.9 2.5 1.9e-11 43.6 1.5 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65805.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) T5orf172 PF10544.9 EAX65806.1 - 0.0032 18.0 0.1 0.0067 17.0 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX65806.1 - 0.019 14.2 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX65806.1 - 0.047 13.5 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX65806.1 - 0.1 12.1 0.4 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 Legume lectin domain DUF5446 PF17522.2 EAX65807.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PTR PF12789.7 EAX65808.1 - 1.3e-16 60.4 1.8 1.3e-16 60.4 1.8 4.9 5 1 0 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX65808.1 - 0.091 12.3 11.1 0.024 14.2 4.7 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX65810.1 - 1.5e-16 60.3 0.5 1.8e-16 60.1 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TALPID3 PF15324.6 EAX65811.1 - 1.3 6.7 12.1 1.5 6.4 12.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DNA_pol_B_2 PF03175.13 EAX65812.1 - 9.1e-12 44.6 0.6 1.9e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65812.1 - 0.035 13.4 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX65812.1 - 0.12 12.4 0.3 9.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type KilA-N PF04383.13 EAX65813.1 - 2.1e-17 63.0 0.1 4.2e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX65814.1 - 1.1e-13 51.0 0.2 2.1e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX65814.1 - 0.099 12.6 2.0 0.61 10.1 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PapD_N PF00345.20 EAX65815.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TMP PF05017.14 EAX65816.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65817.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX65818.1 - 0.074 13.0 10.3 0.12 12.4 10.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Annexin PF00191.20 EAX65819.1 - 0.068 13.2 0.3 0.26 11.4 0.2 1.9 1 1 1 2 2 2 0 Annexin DUF1031 PF06275.11 EAX65819.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Sec23_helical PF04815.15 EAX65819.1 - 0.13 12.1 0.2 0.2 11.5 0.2 1.4 1 1 0 1 1 1 0 Sec23/Sec24 helical domain HARE-HTH PF05066.13 EAX65819.1 - 0.13 12.6 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DUF2791 PF10923.8 EAX65819.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Bd3614-deam PF14439.6 EAX65820.1 - 0.12 12.5 0.5 0.19 11.8 0.5 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase RdRP PF05183.12 EAX65820.1 - 1.7 7.2 17.1 9.7 4.7 1.1 3.8 1 1 3 4 4 4 0 RNA dependent RNA polymerase DUF4107 PF13389.6 EAX65822.1 - 1.1e-72 243.5 3.2 1.4e-72 243.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX65823.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein FAS_N PF17828.1 EAX65824.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX65826.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65826.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX65827.1 - 0.028 14.9 0.5 0.05 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) AAA_11 PF13086.6 EAX65828.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX65828.1 - 0.0034 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65828.1 - 0.0038 17.6 0.0 0.0057 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65828.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX65828.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX65828.1 - 0.04 13.5 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX65828.1 - 0.066 12.9 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX65828.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain PSP PF04046.16 EAX65830.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_D5 PF03288.16 EAX65831.1 - 2.8e-05 24.5 2.1 0.00017 22.0 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX65832.1 - 1.6e-48 164.2 5.2 1.8e-48 164.1 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HD_2 PF12917.7 EAX65833.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme La PF05383.17 EAX65834.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 La domain DNA_pol_B_2 PF03175.13 EAX65835.1 - 5.2e-09 35.5 1.0 8.3e-09 34.8 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX65835.1 - 0.047 12.4 2.3 0.41 9.3 2.3 2.1 1 1 0 1 1 1 0 DNA polymerase family B gpUL132 PF11359.8 EAX65835.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX65835.1 - 0.088 12.8 0.0 0.66 10.0 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Ank_4 PF13637.6 EAX65836.1 - 5.3e-28 97.0 3.3 3e-10 40.4 0.1 4.0 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX65836.1 - 7.2e-27 93.8 0.9 1.1e-13 51.6 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX65836.1 - 1.1e-24 86.1 0.4 2.2e-07 31.0 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65836.1 - 2.2e-22 76.7 1.1 0.00017 21.7 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EAX65836.1 - 6.6e-22 76.9 2.2 0.00021 21.6 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat DNA_pol_B_2 PF03175.13 EAX65840.1 - 1.5e-15 57.0 1.0 2.9e-15 56.1 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65840.1 - 0.047 13.0 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF257 PF03192.13 EAX65841.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65841.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Dehydrin PF00257.19 EAX65842.1 - 0.041 14.4 1.4 0.046 14.3 1.4 1.2 1 0 0 1 1 1 0 Dehydrin Paf1 PF03985.13 EAX65842.1 - 0.55 9.2 6.7 0.69 8.9 6.7 1.0 1 0 0 1 1 1 0 Paf1 PTR PF12789.7 EAX65843.1 - 2.3e-31 107.6 9.6 2.3e-31 107.6 9.6 3.1 3 0 0 3 3 3 1 Phage tail repeat like DUF240 PF03086.14 EAX65843.1 - 0.57 10.1 5.6 1.5 8.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF257 PF03192.13 EAX65844.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX65844.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4107 PF13389.6 EAX65846.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX65846.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4107 PF13389.6 EAX65847.1 - 2.6e-60 203.3 13.6 1.3e-58 197.7 13.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX65847.1 - 0.098 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF737 PF05300.11 EAX65848.1 - 2.3 8.5 7.6 4.4 7.6 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PRCC PF10253.9 EAX65848.1 - 3.9 8.2 13.5 6.4 7.5 13.5 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MULE PF10551.9 EAX65850.1 - 1.2e-11 44.8 0.1 2.4e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX65850.1 - 0.16 12.1 4.7 0.3 11.2 4.7 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain Ank_4 PF13637.6 EAX65853.1 - 5.4e-16 58.7 0.0 0.00012 22.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX65853.1 - 5.3e-15 55.3 0.0 2.5e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX65853.1 - 4.5e-14 52.8 0.1 1.3e-06 28.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX65853.1 - 9.2e-11 41.0 0.0 1.8e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX65853.1 - 1e-08 35.2 0.0 8e-05 22.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Tubulin-binding PF00418.19 EAX65853.1 - 0.18 11.9 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat FAS_N PF17828.1 EAX65855.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF5623 PF18536.1 EAX65857.1 - 0.086 13.1 0.2 0.11 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX65857.1 - 0.87 9.5 9.9 0.29 11.1 4.4 2.4 3 0 0 3 3 3 0 Spo12 family PSP PF04046.16 EAX65858.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX65859.1 - 2.1e-61 203.8 42.0 3e-34 116.9 16.1 5.1 3 2 3 6 6 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX65859.1 - 0.013 15.2 0.1 0.04 13.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX65859.1 - 1.8 8.9 6.4 34 4.9 0.1 4.4 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain ResIII PF04851.15 EAX65861.1 - 2e-05 24.7 0.7 3e-05 24.1 0.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65861.1 - 0.00028 20.7 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65861.1 - 0.00031 21.0 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65861.1 - 0.0015 18.3 0.1 0.0021 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65861.1 - 0.0069 16.7 0.0 0.0086 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65861.1 - 0.033 13.6 0.0 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX65861.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX65861.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX65861.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX65861.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3877 PF12993.7 EAX65862.1 - 0.049 13.5 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) RIH_assoc PF08454.11 EAX65862.1 - 0.08 12.8 0.3 0.35 10.8 0.3 2.1 1 1 1 2 2 2 0 RyR and IP3R Homology associated ANAPC4_WD40 PF12894.7 EAX65863.1 - 0.0012 19.1 0.0 4.8 7.6 0.0 3.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMtag PF10159.9 EAX65863.1 - 0.23 11.7 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated TMP PF05017.14 EAX65865.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65866.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX65869.1 - 1.5e-39 134.5 8.9 5.7e-15 55.7 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX65869.1 - 4.6e-33 112.2 5.6 2.5e-08 34.0 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX65869.1 - 6.5e-32 109.5 4.7 1e-12 48.3 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX65869.1 - 1.1e-29 102.1 6.1 4.1e-11 42.9 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65869.1 - 1.6e-28 95.6 2.2 5.2e-06 26.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat DUF3718 PF12514.8 EAX65869.1 - 8.1e-06 25.9 0.3 15 5.9 0.0 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3718) Imm53 PF15580.6 EAX65869.1 - 0.0028 17.3 6.8 5.1 6.9 0.1 3.3 1 1 2 3 3 3 3 Immunity protein 53 MTHFR PF02219.17 EAX65869.1 - 0.0035 16.7 0.3 25 4.0 0.0 3.7 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase B5 PF03484.15 EAX65869.1 - 0.005 17.1 0.0 38 4.7 0.0 3.1 1 1 2 3 3 3 0 tRNA synthetase B5 domain DUF1965 PF09248.10 EAX65869.1 - 0.006 16.3 0.0 34 4.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) Imm7 PF15585.6 EAX65869.1 - 0.0098 16.2 0.1 2.2 8.6 0.0 2.0 1 1 1 2 2 2 1 Immunity protein 7 DUF503 PF04456.12 EAX65869.1 - 0.018 14.9 1.3 13 5.8 0.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF503) GspH PF12019.8 EAX65869.1 - 0.15 12.5 0.2 3.7 8.0 0.2 2.4 1 1 0 1 1 1 0 Type II transport protein GspH PH_8 PF15409.6 EAX65869.1 - 0.46 10.8 2.2 82 3.6 0.1 3.0 1 1 2 3 3 3 0 Pleckstrin homology domain Sec31 PF11549.8 EAX65869.1 - 3 7.8 12.7 23 5.0 0.3 3.9 4 0 0 4 4 4 0 Protein transport protein SEC31 DUF3839 PF12943.7 EAX65872.1 - 2.9e-128 426.4 5.6 3.3e-128 426.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX65872.1 - 0.064 13.5 0.3 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX65872.1 - 0.22 12.0 2.2 1.1 9.7 1.1 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX65875.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65876.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX65876.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phage_fiber PF03335.13 EAX65878.1 - 0.17 12.1 4.8 1.8 8.9 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX65878.1 - 0.26 11.8 1.8 3.6 8.2 1.9 2.1 1 1 1 2 2 2 0 YmaF family DUF4106 PF13388.6 EAX65879.1 - 9.1e-151 502.8 28.0 7.6e-150 499.8 28.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) HSBP1 PF06825.12 EAX65882.1 - 1.3e-10 40.9 37.1 0.28 11.1 0.1 8.3 5 3 3 8 8 8 4 Heat shock factor binding protein 1 SlyX PF04102.12 EAX65882.1 - 1.8e-05 25.3 22.3 0.52 11.0 2.7 6.5 5 2 0 5 5 5 3 SlyX NPV_P10 PF05531.12 EAX65882.1 - 4.6e-05 23.8 35.4 0.015 15.8 2.0 5.9 5 1 0 5 5 5 2 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EAX65882.1 - 0.00011 22.4 30.6 0.13 12.6 2.1 5.6 5 1 0 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 YPEB PF14620.6 EAX65882.1 - 0.00027 20.4 8.3 0.35 10.2 2.6 3.9 1 1 2 3 3 3 2 YpeB sporulation FliD_N PF02465.18 EAX65882.1 - 0.011 16.4 27.3 0.26 12.0 8.0 4.2 2 1 3 5 5 4 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 EAX65882.1 - 0.012 15.6 31.4 0.17 11.9 8.9 3.9 3 2 0 3 3 3 0 Laminin Domain II Phasin PF05597.11 EAX65882.1 - 0.017 15.2 33.9 1.3 9.1 6.9 5.7 3 2 2 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 EAX65882.1 - 0.17 11.9 13.2 5.1 7.1 0.2 4.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 EAX65882.1 - 0.18 11.6 66.9 0.27 11.1 19.8 5.7 2 2 2 5 5 5 0 Phage minor structural protein GP20 Med10 PF09748.9 EAX65882.1 - 0.2 11.6 3.1 7.1 6.6 0.2 3.0 2 2 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex CLZ PF16526.5 EAX65882.1 - 0.23 11.8 34.2 1.9 8.9 1.9 6.5 5 1 1 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dam1 PF08653.10 EAX65882.1 - 0.31 10.9 20.8 16 5.4 0.0 6.2 5 2 1 6 6 6 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 EAX65882.1 - 0.33 11.1 24.5 5.4 7.2 0.5 4.9 2 2 2 5 5 5 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 EAX65882.1 - 0.36 11.0 34.4 2.5 8.3 1.8 3.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 EAX65882.1 - 0.38 11.0 22.1 0.51 10.6 5.3 4.3 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 EAX65882.1 - 0.44 10.1 18.5 0.084 12.4 2.7 3.7 5 0 0 5 5 5 0 fzo-like conserved region Sec34 PF04136.15 EAX65882.1 - 0.5 10.2 14.3 1.9 8.3 0.9 3.5 3 1 0 3 3 3 0 Sec34-like family PilJ PF13675.6 EAX65882.1 - 0.67 10.0 13.5 5.3 7.1 1.6 3.8 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIVA PF05103.13 EAX65882.1 - 0.67 10.0 36.2 2.8 8.1 7.8 4.2 3 1 1 4 4 4 0 DivIVA protein T7SS_ESX_EspC PF10824.8 EAX65882.1 - 0.82 10.2 10.1 15 6.1 0.4 4.2 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm HOOK PF05622.12 EAX65882.1 - 0.95 7.5 45.5 0.66 8.1 36.7 2.4 1 1 1 2 2 2 0 HOOK protein DUF1471 PF07338.13 EAX65882.1 - 1.1 9.3 3.2 48 4.0 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) DUF1664 PF07889.12 EAX65882.1 - 1.3 9.1 20.1 7.3 6.6 4.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EAX65882.1 - 1.3 9.3 52.6 0.63 10.3 4.8 6.7 5 2 0 5 5 5 0 Haemolysin XhlA DUF484 PF04340.12 EAX65882.1 - 1.4 8.5 5.8 0.38 10.4 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF484 Occludin_ELL PF07303.13 EAX65882.1 - 1.7 9.4 24.5 5.2 7.9 5.3 4.9 3 2 2 5 5 5 0 Occludin homology domain Tropomyosin_1 PF12718.7 EAX65882.1 - 1.9 8.7 54.0 0.87 9.7 22.2 4.0 1 1 2 3 3 3 0 Tropomyosin like Snapin_Pallidin PF14712.6 EAX65882.1 - 2 8.9 21.9 2.6 8.5 4.2 4.8 4 1 0 4 4 4 0 Snapin/Pallidin DUF2730 PF10805.8 EAX65882.1 - 2.1 8.5 23.5 3.4 7.8 3.7 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) Mod_r PF07200.13 EAX65882.1 - 2.8 8.0 24.6 1.3 9.1 1.3 3.8 3 1 1 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Uds1 PF15456.6 EAX65882.1 - 3.4 7.9 40.6 7.4 6.8 11.2 5.0 2 1 3 5 5 5 0 Up-regulated During Septation Allexi_40kDa PF05549.11 EAX65882.1 - 3.7 7.0 17.1 1.1 8.8 4.7 3.4 1 1 3 4 4 4 0 Allexivirus 40kDa protein NPA PF16469.5 EAX65882.1 - 5.6 7.6 38.9 3.1 8.4 4.4 5.8 5 1 1 6 6 6 0 Nematode polyprotein allergen ABA-1 Myb_DNA-bind_4 PF13837.6 EAX65882.1 - 7.3 7.0 14.3 7.9 6.9 0.7 3.5 3 1 0 3 3 2 0 Myb/SANT-like DNA-binding domain Amidase02_C PF12123.8 EAX65883.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX65884.1 - 0.0024 17.5 0.0 0.0066 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX65884.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3417 PF11897.8 EAX65885.1 - 0.11 13.0 0.4 0.12 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX65885.1 - 0.96 9.4 3.3 2 8.4 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S49_N PF08496.10 EAX65885.1 - 2.9 7.9 5.9 2.9 7.9 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4108 PF13390.6 EAX65886.1 - 1.7e-64 216.1 6.7 1.8e-64 215.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX65886.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX65887.1 - 6.7e-06 26.5 0.7 1e-05 25.9 0.7 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX65887.1 - 0.045 14.4 0.1 0.061 13.9 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX65887.1 - 0.056 13.4 0.3 0.09 12.8 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain MULE PF10551.9 EAX65888.1 - 8.5e-11 42.1 1.2 1.2e-10 41.6 0.3 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX65888.1 - 0.02 13.7 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Ank_2 PF12796.7 EAX65890.1 - 2.4e-18 66.5 0.0 4.9e-10 39.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX65890.1 - 3.7e-18 65.4 0.0 3.3e-07 30.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX65890.1 - 1e-16 61.0 0.0 6.9e-06 26.5 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX65890.1 - 9.1e-16 56.4 0.0 2.3e-05 24.4 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX65890.1 - 9.9e-13 47.9 0.0 0.0001 22.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Amidase02_C PF12123.8 EAX65891.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX65892.1 - 2.8e-55 186.2 6.5 3.1e-55 186.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX65892.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide ATP-synt_E PF05680.12 EAX65893.1 - 4.6 7.6 10.2 5.3 7.5 10.2 1.0 1 0 0 1 1 1 0 ATP synthase E chain KilA-N PF04383.13 EAX65895.1 - 1.5e-41 140.8 0.1 2.5e-41 140.0 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX65895.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF1493 PF07377.12 EAX65896.1 - 0.031 14.7 0.8 0.074 13.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX65897.1 - 3.8e-22 78.1 16.7 6.6e-17 61.3 1.8 3.9 4 1 0 4 4 4 2 Phage tail repeat like DUF4738 PF15889.5 EAX65897.1 - 0.033 14.0 2.1 0.089 12.6 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) DUF240 PF03086.14 EAX65897.1 - 0.036 14.0 2.5 0.87 9.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4116 PF13475.6 EAX65897.1 - 0.042 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4106 PF13388.6 EAX65898.1 - 7.5e-74 249.4 9.1 7.5e-74 249.4 9.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) VP4_2 PF08935.10 EAX65898.1 - 0.086 13.4 0.7 0.23 12.1 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit DUF2897 PF11446.8 EAX65899.1 - 0.029 14.3 3.6 0.052 13.4 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX65900.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX65901.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX65901.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX65902.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX65902.1 - 0.03 14.3 0.3 0.039 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX65902.1 - 0.07 13.1 0.2 0.085 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TPR_MLP1_2 PF07926.12 EAX65903.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX65903.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX65903.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX65904.1 - 5.9e-08 32.5 1.1 7.2e-08 32.2 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65904.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX65904.1 - 0.047 13.4 0.1 0.081 12.7 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX65904.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX65905.1 - 2.8e-06 27.0 1.9 2.8e-06 27.0 1.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX65905.1 - 2.8e-05 23.9 0.4 0.28 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX65905.1 - 4.4e-05 23.8 0.2 0.00031 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65905.1 - 0.00028 20.9 4.2 0.00062 19.8 4.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65905.1 - 0.00072 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65905.1 - 0.0041 16.9 2.0 0.008 16.0 1.3 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX65905.1 - 0.01 15.5 0.4 0.01 15.5 0.4 2.5 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX65905.1 - 0.015 15.7 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Epimerase_2 PF02350.19 EAX65905.1 - 0.017 14.0 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase TPK_catalytic PF04263.16 EAX65905.1 - 0.08 13.0 0.7 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX65905.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX65905.1 - 0.1 12.2 0.0 0.31 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX65905.1 - 0.1 13.0 0.1 0.93 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX65905.1 - 0.58 10.4 4.6 8.6 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX65905.1 - 0.97 10.1 10.5 0.49 11.1 1.4 3.5 3 1 0 3 3 3 0 Protein of unknown function, DUF573 AAA_22 PF13401.6 EAX65906.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65906.1 - 6.8e-05 22.9 2.7 0.00012 22.1 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX65906.1 - 9.2e-05 22.2 0.4 0.32 10.7 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX65906.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65906.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65906.1 - 0.0089 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65906.1 - 0.059 12.8 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65906.1 - 0.069 13.6 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65906.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX65906.1 - 0.2 11.9 4.1 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Gly-zipper_Omp PF13488.6 EAX65908.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX65908.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX65908.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX65910.1 - 1.3e-71 240.9 4.5 1.7e-71 240.5 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2939 PF11159.8 EAX65912.1 - 0.022 15.1 0.9 0.035 14.5 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65912.1 - 1.5 7.8 3.7 1.6 7.7 3.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65912.1 - 1.9 8.5 6.8 2.2 8.3 6.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX65913.1 - 4.4e-59 198.5 4.5 4.9e-59 198.4 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX65913.1 - 0.093 13.0 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX65914.1 - 1.9 8.4 3.7 3.6 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2939 PF11159.8 EAX65917.1 - 0.03 14.7 0.1 0.032 14.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX65918.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX65919.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65920.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Podoplanin PF05808.11 EAX65921.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin nsp7 PF08716.10 EAX65921.1 - 0.25 12.0 1.2 0.53 10.9 0.1 2.1 2 1 0 2 2 2 0 nsp7 replicase EphA2_TM PF14575.6 EAX65921.1 - 0.54 11.2 2.1 7.4 7.5 0.4 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain JMY PF15871.5 EAX65922.1 - 0.021 14.2 0.2 0.035 13.4 0.2 1.4 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX65922.1 - 0.18 11.8 2.6 9.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Nematode insulin-related peptide beta type DUF1493 PF07377.12 EAX65923.1 - 0.025 15.0 0.6 0.056 13.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX65924.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX65924.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX65924.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX65924.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Apolipoprotein PF01442.18 EAX65925.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Amidase02_C PF12123.8 EAX65927.1 - 0.002 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_D5 PF03288.16 EAX65930.1 - 0.00013 22.3 3.5 0.001 19.5 3.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX65931.1 - 1.2e-60 203.6 8.0 1.3e-60 203.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DDE_Tnp_4 PF13359.6 EAX65933.1 - 6.3e-21 74.7 0.0 2.2e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX65933.1 - 6.2e-08 32.5 0.3 3.3e-07 30.1 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX65933.1 - 0.00021 21.0 0.2 0.0053 16.4 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX65933.1 - 0.077 12.5 0.2 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DDE_Tnp_1_2 PF13586.6 EAX65933.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain Presenilin PF01080.17 EAX65934.1 - 0.14 10.9 0.5 0.14 10.9 0.5 1.0 1 0 0 1 1 1 0 Presenilin DUF3839 PF12943.7 EAX65935.1 - 6.9e-105 349.8 8.6 7.8e-105 349.7 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX65935.1 - 0.083 12.7 0.5 0.16 11.9 0.5 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase 2_5_RNA_ligase2 PF13563.6 EAX65936.1 - 0.12 12.3 0.0 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Amidase02_C PF12123.8 EAX65939.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX65939.1 - 0.19 11.6 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) MULE PF10551.9 EAX65941.1 - 2.6e-10 40.6 0.7 4.5e-10 39.8 0.1 1.7 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX65941.1 - 0.0048 16.7 0.4 0.076 12.7 0.0 1.8 1 1 1 2 2 2 1 Transposase Transposase_mut PF00872.18 EAX65941.1 - 0.0098 14.8 0.2 0.014 14.3 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family PSP PF04046.16 EAX65942.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65943.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65945.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65946.1 - 0.063 13.9 4.8 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX65947.1 - 3.7e-05 23.3 5.0 6.4e-05 22.5 5.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX65947.1 - 0.0014 18.6 0.2 0.0033 17.4 0.2 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX65947.1 - 0.0082 15.7 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX65947.1 - 0.021 15.1 0.8 0.058 13.7 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) KilA-N PF04383.13 EAX65949.1 - 9e-15 54.5 0.1 1.7e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX65950.1 - 1.7e-25 88.9 8.5 1.7e-25 88.9 8.5 3.4 2 1 1 3 3 3 1 Phage tail repeat like Poxvirus_B22R_C PF13168.6 EAX65950.1 - 0.056 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF4116 PF13475.6 EAX65950.1 - 0.12 12.1 1.2 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) TraH PF06122.11 EAX65950.1 - 0.61 9.3 5.4 0.36 10.1 2.8 1.7 1 1 1 2 2 2 0 Conjugative relaxosome accessory transposon protein DUF2897 PF11446.8 EAX65951.1 - 0.022 14.6 3.0 0.03 14.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OAD_gamma PF04277.13 EAX65951.1 - 7 7.3 5.2 7.3 7.3 5.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4108 PF13390.6 EAX65952.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX65953.1 - 2.1e-07 30.7 0.5 1.4e-06 28.0 0.0 2.3 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX65953.1 - 0.056 13.1 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX65953.1 - 0.096 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX65953.1 - 0.2 11.8 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2939 PF11159.8 EAX65957.1 - 0.02 15.3 0.7 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65957.1 - 1.6 7.7 4.0 1.7 7.6 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX65957.1 - 3.8 8.2 6.6 8.4 7.1 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX65957.1 - 4.1 7.4 7.6 4.4 7.3 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MULE PF10551.9 EAX65958.1 - 1.1e-10 41.7 1.0 1.9e-10 41.0 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX65958.1 - 0.027 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Pox_A32 PF04665.12 EAX65959.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX65960.1 - 3.7e-10 39.3 3.8 1.3e-09 37.4 3.8 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX65960.1 - 0.12 12.4 0.0 0.84 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX65960.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2457 PF10446.9 EAX65961.1 - 2.2 7.4 7.5 3.3 6.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4108 PF13390.6 EAX65962.1 - 1.3e-62 210.0 5.9 1.4e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX65963.1 - 0.054 13.4 3.0 0.11 12.4 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX65963.1 - 0.072 13.5 0.5 0.089 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Pox_A32 PF04665.12 EAX65967.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX65967.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4841 PF16129.5 EAX65968.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) Toxin_R_bind_C PF07951.12 EAX65969.1 - 0.063 12.9 2.2 0.052 13.2 0.6 1.7 2 1 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding Antimicrobial_8 PF08103.11 EAX65969.1 - 8 6.8 6.3 1.7 9.0 0.6 2.8 2 0 0 2 2 2 0 Uperin family TMP PF05017.14 EAX65972.1 - 0.028 14.9 2.8 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX65973.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TFCD_C PF12612.8 EAX65976.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DNA_pol_B_2 PF03175.13 EAX65977.1 - 7.3e-11 41.6 2.8 6.1e-10 38.6 2.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX65977.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) PSP PF04046.16 EAX65978.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX65979.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX65981.1 - 0.02 15.3 0.6 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX65981.1 - 1.6 7.7 4.1 1.7 7.6 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX65981.1 - 4.4 7.3 7.6 4.7 7.2 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 YmaF PF12788.7 EAX65982.1 - 0.1 13.2 1.3 6.9 7.3 0.1 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX65982.1 - 0.42 10.9 7.6 1.1 9.6 0.3 3.0 3 0 0 3 3 3 0 Phage tail fibre repeat PapD_N PF00345.20 EAX65984.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX65985.1 - 1.6e-72 242.9 3.8 2.1e-72 242.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX65986.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX65987.1 - 8.2e-71 239.4 10.0 9e-71 239.3 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX65987.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4106 PF13388.6 EAX65988.1 - 3.8e-21 75.8 2.9 3.8e-21 75.8 2.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF885 PF05960.11 EAX65988.1 - 0.0068 16.1 1.4 0.0073 16.0 1.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) FapA PF03961.13 EAX65988.1 - 0.34 9.5 3.1 0.38 9.3 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4199 PF13858.6 EAX65989.1 - 0.35 11.3 0.4 0.34 11.3 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3839 PF12943.7 EAX65990.1 - 2e-117 390.9 13.1 2.5e-117 390.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX65990.1 - 0.005 16.3 0.1 0.0079 15.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) NTP_transf_6 PF06042.11 EAX65990.1 - 0.028 14.3 0.6 0.1 12.5 0.1 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Aminotran_1_2 PF00155.21 EAX65990.1 - 0.055 12.6 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II KELK PF15796.5 EAX65990.1 - 0.072 13.5 3.1 1.7 9.2 0.0 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ResIII PF04851.15 EAX65991.1 - 0.00018 21.6 3.7 0.00031 20.8 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65991.1 - 0.00051 19.8 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65991.1 - 0.00057 20.2 0.0 0.0011 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65991.1 - 0.0011 18.9 0.9 0.0042 16.9 0.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65991.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX65991.1 - 0.048 13.7 0.6 0.54 10.3 0.6 2.2 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX65991.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX65991.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF573 PF04504.14 EAX65991.1 - 4.7 7.9 11.2 0.29 11.8 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 ResIII PF04851.15 EAX65993.1 - 2.2e-05 24.5 0.2 3e-05 24.1 0.2 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65993.1 - 0.00034 20.4 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX65993.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX65993.1 - 0.0016 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX65993.1 - 0.0054 17.1 0.0 0.0076 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65993.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX65993.1 - 0.056 13.2 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX65993.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX65993.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain T5orf172 PF10544.9 EAX65994.1 - 1.1e-06 29.1 0.2 2.2e-06 28.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX65994.1 - 0.16 12.7 0.3 0.41 11.4 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 AAA_22 PF13401.6 EAX65995.1 - 5.5e-05 23.5 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX65995.1 - 6.5e-05 23.0 2.6 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX65995.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX65995.1 - 0.00077 19.3 0.8 0.0022 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX65995.1 - 0.0027 17.5 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX65995.1 - 0.0075 16.6 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX65995.1 - 0.052 13.0 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX65995.1 - 0.091 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX65995.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX65995.1 - 0.19 12.0 4.1 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX65995.1 - 0.77 10.2 4.2 0.38 11.2 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Annexin PF00191.20 EAX65996.1 - 0.034 14.2 0.3 0.16 12.1 0.2 2.1 1 1 1 2 2 2 0 Annexin DNA_pol_B_2 PF03175.13 EAX65997.1 - 7.8e-12 44.8 0.3 1.5e-11 43.8 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX65997.1 - 0.012 15.0 0.2 0.017 14.4 0.2 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3035 PF11233.8 EAX65998.1 - 0.013 15.7 4.5 0.018 15.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF2486 PF10667.9 EAX65998.1 - 0.018 15.3 7.9 0.021 15.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) TMP PF05017.14 EAX65999.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX66001.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Nucleopor_Nup85 PF07575.13 EAX66002.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Nup85 Nucleoporin Ank PF00023.30 EAX66003.1 - 4.9e-10 39.4 0.0 2.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX66003.1 - 5.2e-10 39.8 0.0 6.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66003.1 - 1.4e-09 38.0 0.0 0.00023 21.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX66003.1 - 5.2e-09 36.5 0.0 0.00033 21.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66003.1 - 3e-07 30.2 0.0 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat SafA PF17073.5 EAX66003.1 - 0.0065 16.4 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Two-component-system connector protein DUF3877 PF12993.7 EAX66004.1 - 0.016 15.0 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4378 PF14309.6 EAX66008.1 - 0.019 15.3 0.2 0.077 13.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX66008.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 La domain Pox_A32 PF04665.12 EAX66010.1 - 4.4e-07 29.6 2.7 4.4e-07 29.6 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66010.1 - 1.9e-05 24.9 0.2 0.00015 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX66010.1 - 0.0001 22.3 1.4 0.00022 21.3 1.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66010.1 - 0.00048 19.9 0.1 0.00088 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX66010.1 - 0.0014 18.3 0.5 0.011 15.4 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX66010.1 - 0.003 17.3 0.2 0.36 10.6 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_11 PF13086.6 EAX66010.1 - 0.0042 16.9 0.5 0.0071 16.2 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX66010.1 - 0.0092 16.3 0.0 0.019 15.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain Elong_Iki1 PF10483.9 EAX66010.1 - 0.055 13.0 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX66010.1 - 0.063 13.7 0.1 0.55 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX66010.1 - 0.066 12.8 0.1 0.21 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX66010.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX66010.1 - 0.11 12.5 0.8 1.6 8.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66010.1 - 0.64 10.2 8.5 6.5 7.0 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Gly-zipper_Omp PF13488.6 EAX66011.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX66011.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX66011.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX66011.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX66011.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX66012.1 - 2.2e-09 37.2 23.0 4.3e-08 33.1 4.8 4.1 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX66012.1 - 0.0077 15.8 13.7 0.45 10.1 0.4 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4795) DUF480 PF04337.12 EAX66012.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF480 YmaF PF12788.7 EAX66012.1 - 0.19 12.3 4.8 16 6.1 0.0 3.3 3 1 0 3 3 3 0 YmaF family Mito_fiss_reg PF05308.11 EAX66015.1 - 0.1 12.7 0.5 0.11 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1493 PF07377.12 EAX66018.1 - 0.059 13.8 0.3 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PapD_N PF00345.20 EAX66020.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX66024.1 - 6.7e-43 146.0 2.9 7.4e-43 145.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX66024.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF5446 PF17522.2 EAX66025.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) TMP PF05017.14 EAX66026.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66027.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX66029.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX66031.1 - 1.6e-121 404.3 12.7 2e-121 404.0 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66031.1 - 0.031 14.7 2.5 1.8 9.0 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX66031.1 - 0.13 11.8 0.6 0.36 10.3 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX66031.1 - 0.19 11.6 1.5 0.54 10.1 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX66032.1 - 1e-08 34.9 0.2 2.3e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66032.1 - 4.5e-05 23.2 0.2 0.00018 21.2 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX66032.1 - 0.029 14.3 1.6 0.044 13.7 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Pox_A32 PF04665.12 EAX66034.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX66036.1 - 1.3e-17 63.8 5.7 1.7e-17 63.5 5.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX66037.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66037.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX66037.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66037.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) FAS_N PF17828.1 EAX66038.1 - 0.0025 17.8 0.3 0.0027 17.7 0.3 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF563 PF04577.14 EAX66039.1 - 2.7e-31 109.3 0.6 3.4e-31 109.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAS_N PF17828.1 EAX66041.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX66041.1 - 0.12 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Saccharop_dh_N PF04455.12 EAX66042.1 - 0.094 13.1 0.1 0.096 13.1 0.1 1.0 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region DUF2939 PF11159.8 EAX66042.1 - 0.15 12.5 0.1 0.16 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Pox_A32 PF04665.12 EAX66043.1 - 1.2e-07 31.5 3.6 1.7e-07 30.9 3.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66043.1 - 0.0034 17.1 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66043.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66043.1 - 0.06 13.1 0.2 0.23 11.2 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66043.1 - 0.072 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX66043.1 - 0.53 10.5 8.2 5.8 7.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX66044.1 - 5.3e-117 389.5 6.8 6.1e-117 389.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX66044.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX66044.1 - 0.22 11.8 1.2 0.42 10.9 1.2 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF1493 PF07377.12 EAX66045.1 - 0.012 16.0 0.4 0.024 15.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX66046.1 - 4.7e-29 101.5 7.4 6.9e-29 101.0 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FAS_N PF17828.1 EAX66047.1 - 0.027 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX66048.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66048.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMP PF05017.14 EAX66049.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX66050.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66050.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX66050.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX66050.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66050.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX66050.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) FAS_N PF17828.1 EAX66051.1 - 0.0042 17.1 0.3 0.0054 16.7 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX66053.1 - 1.1e-37 128.3 1.4 1.5e-37 127.9 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX66053.1 - 0.0091 16.6 0.2 0.038 14.6 0.0 2.0 2 0 0 2 2 2 1 Parathyroid hormone family DUF4378 PF14309.6 EAX66055.1 - 0.036 14.4 0.1 0.22 11.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) DUF2897 PF11446.8 EAX66056.1 - 0.24 11.3 2.7 0.32 10.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX66057.1 - 1.4e-63 213.1 5.2 1.5e-63 213.0 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX66059.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ndc1_Nup PF09531.10 EAX66060.1 - 0.4 9.3 0.6 0.52 8.9 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_B_2 PF03175.13 EAX66061.1 - 4e-10 39.2 3.4 4e-10 39.2 3.4 2.4 1 1 2 3 3 3 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX66061.1 - 0.11 12.1 0.7 0.22 11.1 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX66061.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DNA_pol_B_2 PF03175.13 EAX66063.1 - 4.4e-18 65.4 8.5 9.7e-18 64.3 8.5 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral BRX_N PF13713.6 EAX66064.1 - 6.6e-06 25.8 10.1 0.035 13.9 0.5 4.3 3 0 0 3 3 3 2 Transcription factor BRX N-terminal domain DUF167 PF02594.16 EAX66064.1 - 0.00018 21.5 2.2 0.69 10.1 0.2 3.1 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 FUSC PF04632.12 EAX66064.1 - 0.00054 18.6 22.2 0.0019 16.8 7.9 2.2 1 1 1 2 2 2 2 Fusaric acid resistance protein family XhlA PF10779.9 EAX66064.1 - 0.0026 17.9 78.4 0.06 13.6 6.5 7.9 1 1 7 9 9 9 7 Haemolysin XhlA MitMem_reg PF13012.6 EAX66064.1 - 0.0038 17.6 13.4 0.19 12.1 1.1 3.4 1 1 2 3 3 3 2 Maintenance of mitochondrial structure and function Nup54 PF13874.6 EAX66064.1 - 0.0042 17.2 36.4 0.031 14.4 1.0 5.6 1 1 3 5 5 5 3 Nucleoporin complex subunit 54 ATG16 PF08614.11 EAX66064.1 - 0.2 11.8 68.9 0.47 10.6 21.1 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) TfoX_C PF04994.13 EAX66064.1 - 0.72 10.0 13.0 46 4.2 0.2 5.4 2 1 3 5 5 5 0 TfoX C-terminal domain DUF724 PF05266.14 EAX66064.1 - 1.2 8.9 55.5 0.21 11.4 13.2 4.6 2 2 2 4 4 4 0 Protein of unknown function (DUF724) PTPA PF03095.15 EAX66064.1 - 1.9 7.9 5.6 19 4.6 0.7 2.8 1 1 2 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein Fib_alpha PF08702.10 EAX66064.1 - 3.7 7.7 42.1 2.6 8.2 10.6 4.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DASH_Dad3 PF08656.10 EAX66064.1 - 6.1 7.0 11.5 7.6 6.7 0.8 4.7 2 1 1 4 4 4 0 DASH complex subunit Dad3 DUF16 PF01519.16 EAX66064.1 - 9.1 6.8 52.6 0.22 12.0 10.4 4.9 1 1 3 4 4 3 0 Protein of unknown function DUF16 PTR PF12789.7 EAX66067.1 - 1.4e-23 82.7 8.7 1.4e-23 82.7 8.7 3.8 2 2 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX66067.1 - 0.024 14.4 0.1 0.076 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX66067.1 - 0.31 11.0 7.6 1 9.3 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) Pox_A32 PF04665.12 EAX66072.1 - 5.7e-07 29.2 0.0 6.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX66073.1 - 9.1e-05 22.0 4.6 0.00016 21.2 4.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66073.1 - 0.004 17.2 0.8 0.0081 16.2 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66073.1 - 0.011 15.3 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX66073.1 - 0.063 13.6 1.4 0.17 12.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX66075.1 - 2.9e-07 30.2 0.2 6e-07 29.2 0.1 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein Noggin PF05806.12 EAX66078.1 - 0.15 12.0 0.6 0.22 11.4 0.6 1.2 1 0 0 1 1 1 0 Noggin DUF2939 PF11159.8 EAX66079.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX66079.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX66079.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX66079.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX66081.1 - 1.1e-118 395.0 11.4 1.4e-118 394.7 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66081.1 - 0.055 13.9 0.9 1.8 9.0 0.0 2.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX66081.1 - 0.085 12.7 1.2 0.31 10.9 1.2 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Nab1 PF04902.12 EAX66082.1 - 0.037 14.4 1.7 0.059 13.8 1.7 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 Trypan_PARP PF05887.11 EAX66083.1 - 0.032 14.2 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX66083.1 - 0.14 12.9 4.9 15 6.8 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66084.1 - 0.054 13.4 0.6 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF257 PF03192.13 EAX66085.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX66085.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3839 PF12943.7 EAX66086.1 - 2.8e-78 262.7 6.3 3.2e-78 262.5 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX66086.1 - 0.057 14.3 0.7 2.2 9.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) DUF3839 PF12943.7 EAX66087.1 - 1.4e-25 90.2 4.5 1.7e-25 89.9 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX66087.1 - 0.03 13.5 0.1 0.032 13.4 0.1 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Amidase02_C PF12123.8 EAX66088.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Peripla_BP_2 PF01497.18 EAX66090.1 - 0.0024 17.5 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein DUF3839 PF12943.7 EAX66091.1 - 1e-122 408.2 7.4 1.2e-122 408.0 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX66091.1 - 0.026 14.8 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 Pox_A32 PF04665.12 EAX66092.1 - 6.4e-06 25.8 0.7 7.2e-06 25.6 0.7 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX66092.1 - 0.059 13.7 1.6 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4841 PF16129.5 EAX66092.1 - 0.085 13.1 0.3 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) T5orf172 PF10544.9 EAX66093.1 - 1.2e-06 29.0 0.3 2.4e-06 28.0 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX66093.1 - 0.16 12.7 0.4 0.4 11.4 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3592 PF12158.8 EAX66094.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) HbrB PF08539.11 EAX66094.1 - 3 7.8 6.7 23 4.9 6.7 2.2 1 1 0 1 1 1 0 HbrB-like Pox_A32 PF04665.12 EAX66097.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX66099.1 - 1.9e-41 140.4 0.9 4e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX66099.1 - 0.56 10.2 3.2 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein PapD_N PF00345.20 EAX66102.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PSP PF04046.16 EAX66103.1 - 0.072 13.0 0.8 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66104.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX66105.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX66106.1 - 3.1e-33 113.9 1.2 5.5e-33 113.2 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX66106.1 - 0.021 14.8 6.5 0.032 14.2 6.5 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FPN1 PF06963.12 EAX66106.1 - 0.25 9.9 0.2 0.32 9.5 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX66107.1 - 1.8e-121 404.1 13.3 2.3e-121 403.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66107.1 - 0.036 14.5 3.0 1.8 9.0 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX66107.1 - 0.097 12.2 0.6 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX66107.1 - 0.2 11.5 1.7 0.59 10.0 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX66108.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX66112.1 - 9.8e-57 190.9 7.3 1.1e-56 190.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX66112.1 - 0.11 12.7 0.1 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX66113.1 - 2.9e-05 24.5 2.5 0.0002 21.8 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DNA_pol_B_2 PF03175.13 EAX66114.1 - 4.2e-29 101.7 7.2 6.3e-29 101.2 7.2 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX66117.1 - 8.7e-30 104.0 6.9 1.1e-29 103.7 6.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66117.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX66118.1 - 7.4e-111 369.4 7.5 8.5e-111 369.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX66118.1 - 0.047 13.2 0.8 0.065 12.7 0.7 1.3 1 1 0 1 1 1 0 Z1 domain TMP PF05017.14 EAX66119.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX66121.1 - 2.1e-67 226.3 1.5 2.7e-67 226.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF5592 PF17332.2 EAX66122.1 - 0.69 10.5 3.7 3 8.5 0.7 2.5 1 1 2 3 3 3 0 Family of unknown function (DUF5592) DNA_pol_B_2 PF03175.13 EAX66124.1 - 7.8e-09 34.9 1.3 1.4e-08 34.0 0.7 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX66125.1 - 8.4e-30 104.0 7.9 1.1e-29 103.7 7.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX66126.1 - 2.6e-156 518.2 12.6 3.3e-156 517.9 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66126.1 - 1.7 9.1 5.9 2.1 8.9 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDE_Tnp_4 PF13359.6 EAX66127.1 - 1.5e-18 67.0 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EAX66127.1 - 2.2e-05 24.1 0.8 0.00088 19.0 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX66127.1 - 2.8e-05 23.9 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DNA_pol_B_2 PF03175.13 EAX66128.1 - 2.4e-23 82.7 3.4 4.2e-23 81.9 3.4 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral FAS_N PF17828.1 EAX66129.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX66130.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66130.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66130.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66130.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66130.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX66130.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX66131.1 - 4.9e-42 143.8 0.4 5.6e-42 143.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX66133.1 - 3.3e-07 30.8 0.3 6.6e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PapD_N PF00345.20 EAX66134.1 - 0.045 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66134.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3447 PF11929.8 EAX66135.1 - 2.2e-39 133.3 5.1 2.2e-39 133.3 5.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX66135.1 - 8.3e-07 29.5 0.9 0.0037 17.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX66135.1 - 0.013 16.0 0.3 17 6.3 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EAX66135.1 - 0.043 14.4 2.4 50 4.6 0.0 4.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) DUF3027 PF11228.8 EAX66136.1 - 0.13 12.2 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF1493 PF07377.12 EAX66137.1 - 0.034 14.6 0.8 0.061 13.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX66138.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX66139.1 - 1.7e-117 391.1 12.5 2.2e-117 390.7 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX66139.1 - 0.035 14.7 0.7 0.084 13.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX66139.1 - 0.069 13.6 2.6 1.7 9.2 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase THOC7 PF05615.13 EAX66139.1 - 0.13 12.6 1.1 0.21 11.8 0.1 1.9 3 0 0 3 3 3 0 Tho complex subunit 7 DUF5446 PF17522.2 EAX66140.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX66142.1 - 2.1e-155 515.2 13.6 2.4e-155 515.1 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX66142.1 - 0.046 13.6 0.9 0.19 11.6 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX66142.1 - 0.51 10.6 3.6 1.1 9.5 0.0 2.9 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX66142.1 - 0.94 10.0 8.1 1.6 9.3 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MULE PF10551.9 EAX66143.1 - 1.5e-10 41.4 1.5 2.6e-10 40.6 1.5 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX66143.1 - 0.0011 19.0 1.1 0.004 17.2 1.1 2.0 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX66143.1 - 0.056 12.3 0.6 0.089 11.6 0.6 1.2 1 0 0 1 1 1 0 Transposase, Mutator family TMP PF05017.14 EAX66144.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66145.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TPR_MLP1_2 PF07926.12 EAX66147.1 - 0.034 14.2 3.9 0.034 14.2 3.9 3.2 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein MetOD2 PF18548.1 EAX66147.1 - 0.044 13.9 16.5 0.048 13.8 1.1 3.7 2 2 1 3 3 3 0 Metanogen output domain 2 IFT20 PF14931.6 EAX66147.1 - 0.16 12.2 15.8 0.25 11.5 0.4 2.8 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Citrate_bind PF16114.5 EAX66147.1 - 0.16 11.5 0.5 0.32 10.5 0.0 1.7 2 1 1 3 3 3 0 ATP citrate lyase citrate-binding Fez1 PF06818.15 EAX66147.1 - 1.4 9.3 24.4 73 3.7 14.5 2.7 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 EAX66147.1 - 1.5 8.8 11.9 1.2 9.1 6.7 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF641 PF04859.12 EAX66147.1 - 1.6 9.1 17.1 2.3 8.6 6.2 3.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) NurA PF09376.10 EAX66147.1 - 1.8 8.2 10.8 0.19 11.4 3.1 2.0 1 1 1 2 2 2 0 NurA domain HR1 PF02185.16 EAX66147.1 - 2 8.6 15.6 0.69 10.1 8.7 3.6 3 1 0 3 3 3 0 Hr1 repeat FAS_N PF17828.1 EAX66148.1 - 0.0072 16.3 0.1 0.0088 16.1 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Spo12 PF05032.12 EAX66149.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Autophagy_N PF03986.13 EAX66150.1 - 2e-07 31.1 3.5 0.048 13.6 0.2 4.2 2 1 1 3 3 3 3 Autophagocytosis associated protein (Atg3), N-terminal domain MORN_2 PF07661.13 EAX66150.1 - 0.0065 16.6 0.5 62 4.3 0.0 5.0 6 0 0 6 6 6 1 MORN repeat variant Nab1 PF04902.12 EAX66151.1 - 0.029 14.8 1.1 0.036 14.5 1.1 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 DUF5365 PF17326.2 EAX66153.1 - 0.019 15.4 0.4 0.029 14.8 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5365) KilA-N PF04383.13 EAX66154.1 - 6.9e-30 103.2 0.3 1.7e-29 101.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX66154.1 - 0.0073 16.9 0.1 0.022 15.4 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Mito_fiss_reg PF05308.11 EAX66155.1 - 0.16 12.0 0.4 0.17 12.0 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Trypan_PARP PF05887.11 EAX66156.1 - 0.049 13.6 10.2 0.074 13.0 10.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 EAX66159.1 - 0.038 14.0 7.9 0.059 13.4 7.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX66159.1 - 2.8 8.4 4.8 4.1 7.9 4.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX66161.1 - 1.1e-17 64.1 9.2 3.9e-17 62.3 9.2 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4795 PF16043.5 EAX66163.1 - 0.027 14.1 3.8 0.077 12.6 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FmdE PF02663.14 EAX66163.1 - 0.14 12.2 1.1 0.57 10.2 0.2 2.0 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Phage_fiber PF03335.13 EAX66163.1 - 3.5 8.0 6.5 9.4 6.7 0.7 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX66164.1 - 6.4e-17 61.6 3.3 7.2e-17 61.4 3.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_11 PF13086.6 EAX66168.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX66168.1 - 0.0047 17.2 0.0 0.0075 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX66168.1 - 0.015 14.7 0.1 0.018 14.5 0.1 1.2 1 1 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX66168.1 - 0.019 15.0 0.1 0.027 14.5 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX66168.1 - 0.024 15.0 0.1 0.036 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX66168.1 - 0.039 13.5 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX66168.1 - 0.068 12.9 0.0 0.076 12.7 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4108 PF13390.6 EAX66169.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX66170.1 - 3.3e-05 24.3 0.5 5.1e-05 23.7 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66170.1 - 0.0089 16.6 0.2 0.012 16.2 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66170.1 - 0.06 13.3 0.3 0.084 12.9 0.3 1.3 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX66171.1 - 5.3e-05 22.8 3.0 8.5e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66171.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66171.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX66171.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PRA-PH PF01503.17 EAX66172.1 - 0.33 11.4 2.8 0.53 10.8 2.8 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Pox_A32 PF04665.12 EAX66175.1 - 5.2e-07 29.4 0.1 9.6e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein PBAN PF05874.11 EAX66175.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Amidase02_C PF12123.8 EAX66176.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Swi5 PF07061.11 EAX66177.1 - 0.12 12.5 0.7 0.41 10.8 0.7 1.9 1 1 0 1 1 1 0 Swi5 Tho2 PF11262.8 EAX66178.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX66178.1 - 0.079 13.6 0.9 0.13 13.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX66178.1 - 0.38 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX66179.1 - 3.9e-17 62.1 0.8 9.2e-17 60.9 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX66179.1 - 0.0097 16.5 0.0 0.021 15.4 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family FAS_N PF17828.1 EAX66181.1 - 0.0071 16.3 0.1 0.0081 16.2 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX66181.1 - 0.064 13.5 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Pox_A32 PF04665.12 EAX66182.1 - 3.6e-06 26.6 2.3 3.6e-06 26.6 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66182.1 - 2.7e-05 24.5 0.2 0.00022 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66182.1 - 4.2e-05 23.4 0.3 0.31 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66182.1 - 0.00014 21.9 3.3 0.00031 20.8 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66182.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66182.1 - 0.0013 18.6 0.6 0.0038 17.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66182.1 - 0.0019 17.9 0.6 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66182.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX66182.1 - 0.062 12.9 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX66182.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX66182.1 - 0.075 13.4 0.1 0.64 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66182.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66182.1 - 0.44 10.8 4.3 9.5 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX66183.1 - 2.2e-05 24.8 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66183.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Imm70 PF15601.6 EAX66186.1 - 0.0051 16.3 17.0 2.4 7.7 0.1 5.6 1 1 7 8 8 8 8 Immunity protein 70 DALR_1 PF05746.15 EAX66188.1 - 0.13 12.4 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 DALR anticodon binding domain Amidase02_C PF12123.8 EAX66190.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX66192.1 - 1.3e-21 76.4 6.7 1.3e-21 76.4 6.7 3.2 3 1 0 3 3 3 1 Phage tail repeat like DUF3839 PF12943.7 EAX66193.1 - 1.3e-145 483.2 9.7 1.7e-145 482.9 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX66193.1 - 0.17 12.4 1.4 6.1 7.4 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX66193.1 - 0.92 10.0 5.4 2.2 8.8 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AbiJ_NTD4 PF18863.1 EAX66194.1 - 0.022 15.2 0.3 0.05 14.1 0.1 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX66194.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 VirK protein Glyco_hydro_30C PF17189.4 EAX66195.1 - 8.2e-08 32.4 2.1 1.5e-07 31.5 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EAX66195.1 - 3.2e-05 23.1 0.6 4.6e-05 22.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ank_4 PF13637.6 EAX66196.1 - 3.5e-12 46.6 0.0 4e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66196.1 - 2.2e-11 44.2 0.1 2.6e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66196.1 - 5.7e-11 42.4 0.1 1.4e-07 31.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66196.1 - 2.2e-07 30.6 0.0 0.051 14.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX66196.1 - 3.5e-05 24.1 0.0 0.36 11.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Tubulin-binding PF00418.19 EAX66196.1 - 0.021 14.8 0.3 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat Pro_CA PF00484.19 EAX66196.1 - 0.099 12.9 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Carbonic anhydrase CheD PF03975.13 EAX66196.1 - 0.1 12.7 0.2 1.6 8.8 0.1 2.0 1 1 1 2 2 2 0 CheD chemotactic sensory transduction DUF4795 PF16043.5 EAX66197.1 - 0.0095 15.6 0.2 0.013 15.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX66197.1 - 0.94 9.8 4.6 9.6 6.7 0.2 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat Pox_D5 PF03288.16 EAX66199.1 - 2e-05 25.0 2.6 0.0001 22.7 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like PcfK PF14058.6 EAX66200.1 - 0.09 13.1 10.7 0.11 12.7 10.7 1.1 1 0 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX66200.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 1 1 2 2 2 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX66200.1 - 5.7 6.9 5.9 13 5.7 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX66201.1 - 1.3e-63 213.1 6.8 1.5e-63 213.0 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX66202.1 - 1.3 8.6 4.6 9.9 5.7 4.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX66202.1 - 9.1 6.4 14.0 0.13 12.3 2.4 3.5 4 1 0 4 4 4 0 Phage tail repeat like TMP PF05017.14 EAX66203.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66204.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX66206.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX66207.1 - 0.085 12.9 0.3 0.085 12.9 0.3 4.1 4 1 0 4 4 4 0 Phage tail repeat like GPS2_interact PF15784.5 EAX66208.1 - 0.077 13.4 1.5 0.12 12.9 1.5 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX66208.1 - 0.099 11.6 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4106 PF13388.6 EAX66209.1 - 1.8e-153 511.7 27.8 3e-153 511.0 27.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX66209.1 - 0.00027 21.2 0.2 0.018 15.4 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX66209.1 - 0.0091 15.8 0.1 0.0091 15.8 0.1 2.3 2 0 0 2 2 2 1 Putative transmembrane protein (Alph_Pro_TM) VP4_2 PF08935.10 EAX66209.1 - 0.094 13.3 0.7 0.23 12.1 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX66209.1 - 0.22 11.9 6.6 6.3 7.2 0.5 3.5 3 0 0 3 3 3 0 WYL domain DUF4108 PF13390.6 EAX66211.1 - 3.2e-63 211.9 5.9 3.5e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX66212.1 - 3e-41 139.8 0.9 5.7e-41 138.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX66212.1 - 0.34 10.9 2.8 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein TMEM154 PF15102.6 EAX66214.1 - 0.00087 19.2 0.6 0.0012 18.8 0.6 1.2 1 0 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 EAX66214.1 - 0.1 12.5 5.4 0.24 11.2 5.0 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF5123 PF17161.4 EAX66214.1 - 0.22 12.6 3.0 0.8 10.8 3.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Vpu PF00558.19 EAX66214.1 - 0.37 10.6 3.0 0.56 10.0 3.0 1.2 1 0 0 1 1 1 0 Vpu protein ASFV_J13L PF05568.11 EAX66214.1 - 0.4 10.4 6.1 0.54 10.0 6.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 EAX66214.1 - 1.1 8.8 5.0 2.1 8.0 5.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syndecan PF01034.20 EAX66214.1 - 5.4 7.0 7.0 4.6 7.2 3.7 2.2 2 0 0 2 2 2 0 Syndecan domain KilA-N PF04383.13 EAX66215.1 - 7.6e-41 138.5 0.1 7.6e-41 138.5 0.1 1.4 2 0 0 2 2 2 1 KilA-N domain Cir_Bir_Yir PF06022.11 EAX66217.1 - 0.025 14.1 1.9 0.035 13.6 1.9 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir HAUS-augmin3 PF14932.6 EAX66217.1 - 0.026 14.1 2.5 0.037 13.6 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DNA_pol_B_2 PF03175.13 EAX66218.1 - 1.1e-20 74.0 3.9 2e-20 73.1 3.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66218.1 - 0.059 12.7 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein RPA_C PF08784.11 EAX66219.1 - 0.0019 18.8 0.0 0.0033 18.1 0.0 1.4 1 1 0 1 1 1 1 Replication protein A C terminal RMI2 PF16100.5 EAX66219.1 - 0.091 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 PqqD PF05402.12 EAX66219.1 - 0.18 12.1 0.4 26 5.2 0.1 2.3 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4108 PF13390.6 EAX66220.1 - 1.2e-64 216.6 6.2 1.3e-64 216.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX66221.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Ly49 PF08391.10 EAX66221.1 - 0.3 11.4 2.9 0.36 11.2 2.9 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX66221.1 - 0.96 9.4 2.8 1.6 8.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) HNH_3 PF13392.6 EAX66222.1 - 3.4e-07 29.9 0.3 6.1e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF1840 PF08895.11 EAX66222.1 - 0.00047 20.4 1.2 0.00087 19.6 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1840) Tim54 PF11711.8 EAX66222.1 - 0.0051 15.6 0.9 0.0066 15.3 0.9 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Radial_spoke PF04712.12 EAX66222.1 - 0.079 11.9 9.1 0.091 11.7 9.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Cytomega_UL84 PF06284.11 EAX66222.1 - 0.23 9.9 3.7 0.27 9.6 3.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 EAX66222.1 - 0.26 9.5 3.0 0.27 9.5 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EAX66222.1 - 0.89 7.6 10.2 1 7.4 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EAX66222.1 - 2.8 7.2 8.1 3.7 6.8 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF740 PF05340.12 EAX66222.1 - 5.2 5.7 6.2 6.1 5.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Secretin_N_2 PF07655.13 EAX66223.1 - 0.51 10.9 10.1 0.93 10.1 1.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain TMP PF05017.14 EAX66224.1 - 0.12 13.0 7.4 6.1 8.0 0.9 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66225.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX66226.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX66227.1 - 1e-97 328.1 4.4 1e-97 328.1 4.4 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX66227.1 - 0.092 11.3 3.5 0.11 11.1 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3452 PF11934.8 EAX66227.1 - 0.1 12.2 0.5 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX66227.1 - 1.8 8.5 4.4 0.53 10.3 0.8 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Pox_A32 PF04665.12 EAX66229.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66229.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66229.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66229.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66229.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66229.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66229.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) TMP PF05017.14 EAX66230.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66231.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX66232.1 - 0.069 13.0 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66233.1 - 0.15 12.8 6.1 11 7.2 0.2 3.3 3 1 1 4 4 4 0 TMP repeat PSP PF04046.16 EAX66234.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX66236.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66236.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4107 PF13389.6 EAX66237.1 - 6.7e-72 240.9 4.4 8.9e-72 240.5 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX66238.1 - 0.0036 16.9 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase 2_5_RNA_ligase2 PF13563.6 EAX66239.1 - 0.19 11.7 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily PapD_N PF00345.20 EAX66240.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Spo12 PF05032.12 EAX66241.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF2939 PF11159.8 EAX66243.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66243.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX66244.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX66246.1 - 5.6e-10 38.7 0.9 8.2e-10 38.1 0.9 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66246.1 - 0.084 12.9 0.0 0.76 9.8 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX66246.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DNA_pol_B PF00136.21 EAX66246.1 - 0.11 11.2 2.2 0.95 8.1 2.2 2.3 1 1 0 1 1 1 0 DNA polymerase family B Pox_D5 PF03288.16 EAX66247.1 - 0.00014 22.3 3.1 0.00077 19.9 3.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX66247.1 - 0.032 13.3 1.1 0.046 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) FAS_N PF17828.1 EAX66248.1 - 0.0082 16.2 0.1 0.0098 15.9 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF1493 PF07377.12 EAX66249.1 - 0.042 14.3 0.5 0.094 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX66249.1 - 0.78 9.8 3.8 9.8 6.3 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4108 PF13390.6 EAX66251.1 - 5e-39 133.5 1.3 5.8e-39 133.3 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX66254.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX66255.1 - 2.2e-71 239.3 3.5 2.9e-71 238.9 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX66256.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX66257.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ANAPC4_WD40 PF12894.7 EAX66258.1 - 0.0062 16.8 0.0 4.9 7.5 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FAS_N PF17828.1 EAX66260.1 - 0.026 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX66261.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66261.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMP PF05017.14 EAX66263.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX66264.1 - 1.3e-77 260.6 6.4 1.4e-77 260.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX66268.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66269.1 - 0.064 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX66272.1 - 1e-72 243.6 4.8 1.2e-72 243.4 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX66272.1 - 0.06 11.8 1.1 0.087 11.2 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX66273.1 - 0.022 14.6 1.0 0.034 14.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) FAS_N PF17828.1 EAX66274.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX66275.1 - 9.4e-23 80.8 5.0 1.2e-22 80.4 5.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral GGDEF PF00990.21 EAX66276.1 - 0.065 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX66277.1 - 8.4e-61 204.1 8.0 9.4e-61 203.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VirE PF05272.11 EAX66279.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX66279.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX66279.1 - 0.084 11.8 0.2 7.4 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF4106 PF13388.6 EAX66280.1 - 1.4e-190 633.9 28.1 5.3e-117 391.6 10.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX66280.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DDE_Tnp_4 PF13359.6 EAX66281.1 - 1.6e-33 115.6 0.1 2.3e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX66281.1 - 1.5e-07 31.3 0.7 2.7e-06 27.2 0.7 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX66281.1 - 3.8e-05 23.3 0.8 0.0012 18.5 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 EAX66281.1 - 0.12 12.7 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain TMP PF05017.14 EAX66284.1 - 0.58 11.0 8.1 12 7.1 0.3 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX66285.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66286.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP BRO1 PF03097.18 EAX66287.1 - 0.05 12.4 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX66287.1 - 0.17 11.5 2.0 0.46 10.1 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX66287.1 - 0.84 10.0 16.0 4.1 7.8 2.1 3.9 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX66287.1 - 2 9.0 6.8 16 6.1 0.2 3.4 3 1 0 3 3 3 0 YmaF family DUF2897 PF11446.8 EAX66288.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX66289.1 - 1.6e-15 56.9 1.2 3.1e-15 56.0 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66289.1 - 0.058 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PSP PF04046.16 EAX66292.1 - 0.067 13.1 0.3 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66292.1 - 2.9 8.9 4.6 50 5.3 0.1 3.2 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX66294.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX66294.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX66294.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Pox_A32 PF04665.12 EAX66296.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF2939 PF11159.8 EAX66297.1 - 0.022 15.2 0.7 0.029 14.8 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX66297.1 - 2.1 7.3 4.8 2.3 7.2 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX66297.1 - 4 7.5 8.4 4.3 7.3 8.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX66298.1 - 0.0051 16.8 0.3 0.0074 16.3 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX66298.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Pox_A32 PF04665.12 EAX66299.1 - 6.1e-07 29.1 4.9 6.5e-07 29.1 3.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66299.1 - 8e-06 26.2 0.2 0.00013 22.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66299.1 - 5e-05 23.1 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66299.1 - 0.00025 21.1 3.0 0.00061 19.8 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66299.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66299.1 - 0.0018 18.1 0.5 0.0036 17.1 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66299.1 - 0.002 17.8 0.4 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66299.1 - 0.0079 16.5 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX66299.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX66299.1 - 0.08 13.3 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein PhoH PF02562.16 EAX66299.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66299.1 - 0.39 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GPS2_interact PF15784.5 EAX66300.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX66300.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain CREPT PF16566.5 EAX66303.1 - 0.032 14.4 0.3 0.067 13.4 0.3 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX66303.1 - 0.49 10.6 4.9 0.29 11.3 1.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SH3BGR PF04908.15 EAX66304.1 - 0.077 13.2 1.0 0.14 12.4 1.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2939 PF11159.8 EAX66305.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66305.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Annexin PF00191.20 EAX66306.1 - 0.036 14.1 0.9 0.18 11.9 0.2 2.5 2 1 1 3 3 3 0 Annexin PapD_N PF00345.20 EAX66307.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66307.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX66309.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66309.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX66309.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66309.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Mid2 PF04478.12 EAX66310.1 - 0.0005 19.9 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX66310.1 - 0.00064 19.4 2.0 0.0011 18.7 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX66310.1 - 0.00085 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX66310.1 - 0.0024 18.1 0.6 0.059 13.7 0.3 2.3 2 1 0 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 EAX66310.1 - 0.0041 17.0 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX66310.1 - 0.0054 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX66310.1 - 0.0069 16.6 0.7 0.011 15.9 0.7 1.5 1 1 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 EAX66310.1 - 0.029 14.1 0.1 0.043 13.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX66310.1 - 0.034 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 EAX66310.1 - 0.052 14.4 0.1 0.17 12.8 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 EAX66310.1 - 0.052 11.9 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 EAX66310.1 - 0.058 12.8 3.5 0.099 12.0 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PTP_tm PF18861.1 EAX66310.1 - 0.083 12.9 0.9 0.21 11.6 0.3 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MMM1 PF10296.9 EAX66310.1 - 0.088 11.8 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ABC2_membrane_3 PF12698.7 EAX66310.1 - 0.096 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5385 PF17359.2 EAX66310.1 - 0.11 12.0 0.7 1.3 8.5 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) SKG6 PF08693.10 EAX66310.1 - 0.11 11.9 4.0 0.2 11.1 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gemini_mov PF01708.16 EAX66310.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Otopetrin PF03189.13 EAX66310.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Otopetrin AAA_22 PF13401.6 EAX66311.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX66311.1 - 7.8e-05 22.7 3.0 0.00014 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX66311.1 - 0.00013 21.8 0.4 0.41 10.3 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX66311.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66311.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX66311.1 - 0.0088 16.4 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX66311.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX66311.1 - 0.067 13.6 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX66311.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX66311.1 - 0.16 12.2 4.2 4.7 7.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) FAS_N PF17828.1 EAX66312.1 - 0.0099 15.9 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX66314.1 - 1.9e-62 210.9 4.4 2.4e-62 210.6 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX66314.1 - 0.02 14.9 0.2 7.3 6.6 0.3 2.3 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region APC_u14 PF16635.5 EAX66314.1 - 0.18 12.3 2.6 0.34 11.5 2.6 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DUF4108 PF13390.6 EAX66316.1 - 2.6e-41 140.9 2.6 2.9e-41 140.7 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX66316.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Ank_4 PF13637.6 EAX66319.1 - 1.2e-22 79.9 3.5 2e-10 41.0 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66319.1 - 6.3e-20 71.6 0.2 1.7e-09 38.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66319.1 - 1.4e-17 63.5 0.4 1.4e-07 31.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66319.1 - 2.3e-15 55.1 1.4 0.0069 16.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EAX66319.1 - 3.7e-15 55.6 2.5 0.0072 16.7 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat PSP PF04046.16 EAX66320.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66321.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4116 PF13475.6 EAX66322.1 - 0.01 15.5 0.1 0.055 13.2 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX66322.1 - 0.052 12.5 0.8 0.077 12.0 0.5 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX66322.1 - 0.069 13.6 5.0 0.13 12.7 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX66322.1 - 0.085 12.6 5.8 0.082 12.7 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PTR PF12789.7 EAX66322.1 - 0.22 11.6 0.1 0.22 11.6 0.1 4.2 2 1 2 4 4 4 0 Phage tail repeat like Transposase_24 PF03004.14 EAX66322.1 - 0.55 10.3 4.9 2.5 8.2 3.7 2.6 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) HTH_32 PF13565.6 EAX66323.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PhaP_Bmeg PF09602.10 EAX66324.1 - 0.052 13.5 0.1 0.6 10.0 0.1 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PHM7_cyt PF14703.6 EAX66324.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Homez PF11569.8 EAX66324.1 - 0.22 11.0 0.5 0.44 10.1 0.5 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TMP PF05017.14 EAX66328.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat rve PF00665.26 EAX66330.1 - 1.5e-20 73.6 0.0 2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX66330.1 - 2.1e-07 31.2 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 EAX66330.1 - 1.1e-05 25.2 0.5 8.3e-05 22.3 0.5 2.4 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_1 PF01609.21 EAX66330.1 - 0.039 13.6 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 Transposase DDE domain Alpha-amylase_N PF02903.14 EAX66330.1 - 0.047 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain Pox_D5 PF03288.16 EAX66331.1 - 3.5e-05 24.2 2.3 0.00017 22.0 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX66332.1 - 2.8e-55 186.2 4.6 3e-55 186.1 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX66332.1 - 0.087 13.1 0.1 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DNA_pol_B_2 PF03175.13 EAX66336.1 - 8.6e-23 80.9 2.1 9.9e-23 80.7 2.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX66338.1 - 0.036 14.1 3.5 0.036 14.1 3.5 2.5 2 1 0 2 2 2 0 Phage tail repeat like DUF4795 PF16043.5 EAX66338.1 - 0.22 11.1 0.4 0.35 10.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX66338.1 - 5.6 7.4 7.6 17 5.9 1.4 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF5365 PF17326.2 EAX66339.1 - 0.029 14.8 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX66339.1 - 0.044 14.1 0.5 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 PWI domain Pox_A32 PF04665.12 EAX66342.1 - 3e-05 23.6 2.3 3e-05 23.6 2.3 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66342.1 - 0.0034 17.4 0.9 0.0062 16.6 0.2 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66342.1 - 0.0056 16.3 0.4 0.011 15.3 0.4 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX66342.1 - 0.032 14.5 1.0 0.082 13.2 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX66342.1 - 0.048 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAX66343.1 - 9.4e-131 434.5 6.8 1.1e-130 434.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX66343.1 - 0.055 13.0 0.8 0.11 12.0 0.4 1.6 1 1 1 2 2 2 0 Z1 domain Ly49 PF08391.10 EAX66344.1 - 0.42 11.0 3.2 0.86 10.0 3.2 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4337 PF14235.6 EAX66344.1 - 0.84 9.7 4.3 1.2 9.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DNA_pol_B_2 PF03175.13 EAX66345.1 - 5.6e-23 81.5 4.6 7.4e-23 81.2 4.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4106 PF13388.6 EAX66346.1 - 2.3e-71 241.2 9.7 2.3e-71 241.2 9.7 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX66346.1 - 0.19 12.0 1.9 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Kidney androgen-regulated Phage_fiber_2 PF03406.13 EAX66346.1 - 2.9 7.5 7.8 0.97 9.0 1.4 3.1 3 0 0 3 3 3 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX66347.1 - 5.4e-07 29.3 4.0 5.4e-07 29.3 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66347.1 - 3.5e-06 27.3 0.2 2.9e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66347.1 - 6.1e-06 26.1 0.3 0.077 12.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66347.1 - 2e-05 24.7 3.3 4.3e-05 23.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66347.1 - 0.0002 21.2 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66347.1 - 0.0004 20.2 0.9 0.00079 19.3 0.9 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66347.1 - 0.002 17.8 0.4 0.014 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66347.1 - 0.005 17.2 0.0 0.0097 16.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX66347.1 - 0.023 14.3 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX66347.1 - 0.041 14.3 0.1 0.33 11.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66347.1 - 0.079 12.4 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EAX66347.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX66347.1 - 0.15 12.4 4.0 3.9 7.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX66348.1 - 1.1e-15 57.8 3.0 1.8e-15 57.1 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX66348.1 - 0.047 14.0 0.3 0.13 12.6 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX66348.1 - 0.05 14.1 0.3 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Amidase02_C PF12123.8 EAX66349.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Trypan_PARP PF05887.11 EAX66350.1 - 0.093 12.7 6.6 0.14 12.1 6.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX66350.1 - 2.5 8.5 5.1 3.6 8.0 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX66351.1 - 2.8e-18 66.3 1.1 4.2e-18 65.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX66351.1 - 0.0074 16.8 0.5 0.026 15.1 0.2 2.0 2 0 0 2 2 2 1 T5orf172 domain RUN PF02759.19 EAX66351.1 - 0.076 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 RUN domain DNA_pol_B_2 PF03175.13 EAX66352.1 - 1.7e-10 40.4 2.5 1e-09 37.8 2.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66352.1 - 0.071 13.1 0.0 0.68 10.0 0.0 2.5 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX66352.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX66353.1 - 4e-15 55.7 2.6 4e-15 55.7 2.6 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral TFCD_C PF12612.8 EAX66353.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal PSP PF04046.16 EAX66354.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1731 PF08338.11 EAX66355.1 - 0.22 11.4 0.2 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) GPS2_interact PF15784.5 EAX66356.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX66356.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX66357.1 - 0.013 15.2 0.1 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AbiJ_NTD4 PF18863.1 EAX66358.1 - 0.025 15.0 0.6 0.033 14.7 0.6 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 PTR PF12789.7 EAX66360.1 - 2.7e-51 171.5 31.7 3.2e-32 110.4 14.4 4.0 3 2 1 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX66360.1 - 0.3 10.7 7.5 0.96 9.0 7.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4404 PF14357.6 EAX66360.1 - 4.7 7.9 6.8 8.4 7.1 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DNA_pol_B_2 PF03175.13 EAX66361.1 - 1.2e-11 44.2 0.8 2.2e-11 43.3 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66361.1 - 0.014 14.7 0.2 0.021 14.2 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4890 PF16231.5 EAX66362.1 - 0.007 16.8 0.7 0.007 16.8 0.7 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4890) NAD_binding_1 PF00175.21 EAX66362.1 - 0.048 14.3 0.1 0.1 13.3 0.1 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain KELK PF15796.5 EAX66362.1 - 0.077 13.5 14.0 0.86 10.1 5.5 2.7 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 EAX66362.1 - 0.28 10.5 6.8 0.5 9.7 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5315 PF17242.2 EAX66362.1 - 3.4 7.5 9.3 0.21 11.4 1.4 2.7 3 1 0 3 3 3 0 Disordered region of unknown function (DUF5315) DUF3839 PF12943.7 EAX66363.1 - 1.3e-80 270.3 10.0 1.7e-80 270.0 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX66363.1 - 0.059 13.9 0.5 0.098 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Laminin_I PF06008.14 EAX66366.1 - 3e-13 50.1 23.7 0.00074 19.3 2.3 4.0 1 1 3 4 4 4 4 Laminin Domain I Sec34 PF04136.15 EAX66366.1 - 1.2e-05 25.3 46.8 0.13 12.2 5.5 5.0 1 1 4 5 5 5 4 Sec34-like family GCN5L1 PF06320.13 EAX66366.1 - 1.7e-05 24.9 8.4 4.3 7.5 0.1 5.0 1 1 4 5 5 5 1 GCN5-like protein 1 (GCN5L1) KASH_CCD PF14662.6 EAX66366.1 - 0.00028 20.8 26.2 0.013 15.3 12.0 2.6 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 EAX66366.1 - 0.0003 21.4 8.8 6.2 7.5 1.7 4.5 1 1 1 2 2 2 1 Initiation control protein YabA DUF3552 PF12072.8 EAX66366.1 - 0.00058 19.3 16.7 0.13 11.7 1.2 4.3 1 1 3 4 4 4 3 Domain of unknown function (DUF3552) UPF0449 PF15136.6 EAX66366.1 - 0.0024 18.3 26.7 1.3 9.5 1.7 4.7 1 1 2 3 3 3 1 Uncharacterised protein family UPF0449 Ax_dynein_light PF10211.9 EAX66366.1 - 0.0053 16.7 3.6 8.6 6.3 0.1 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain JIP_LZII PF16471.5 EAX66366.1 - 0.0059 16.8 13.9 3.1 8.0 0.2 5.8 1 1 5 6 6 6 1 JNK-interacting protein leucine zipper II BRE1 PF08647.11 EAX66366.1 - 0.0072 16.4 20.7 0.32 11.1 1.4 3.7 1 1 2 3 3 3 2 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 EAX66366.1 - 0.0084 16.1 28.0 0.6 10.1 3.8 3.5 1 1 3 4 4 4 4 Laminin Domain II ZapB PF06005.12 EAX66366.1 - 0.011 16.2 14.4 14 6.2 0.1 4.9 1 1 4 5 5 5 0 Cell division protein ZapB COG7 PF10191.9 EAX66366.1 - 0.017 13.4 31.2 0.094 10.9 6.2 3.9 1 1 2 3 3 3 0 Golgi complex component 7 (COG7) APG6_N PF17675.1 EAX66366.1 - 0.023 15.2 30.2 0.87 10.1 5.7 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EAX66366.1 - 0.026 14.6 39.9 0.28 11.3 13.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 EAX66366.1 - 0.072 13.3 26.1 4.2 7.6 2.0 3.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EAX66366.1 - 0.22 11.6 17.0 1.9 8.6 1.4 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EAX66366.1 - 0.53 9.6 40.8 2.2 7.5 7.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) TACC_C PF05010.14 EAX66366.1 - 0.54 10.0 9.0 11 5.8 3.1 3.1 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF948 PF06103.11 EAX66366.1 - 0.64 10.3 13.7 6.2 7.1 1.2 4.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 EAX66366.1 - 0.89 8.0 35.5 0.095 11.2 21.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.11 EAX66366.1 - 2.8 6.7 24.9 4.2 6.2 11.9 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein PI_PP_I PF18363.1 EAX66366.1 - 3.9 7.7 11.9 39 4.5 0.3 4.3 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain Prominin PF05478.11 EAX66366.1 - 6.9 4.5 24.3 4.6 5.1 4.6 2.9 1 1 2 3 3 3 0 Prominin CRR7 PF12095.8 EAX66366.1 - 7.7 7.0 20.6 41 4.7 0.3 5.8 1 1 4 5 5 5 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1493 PF07377.12 EAX66367.1 - 0.031 14.8 0.8 0.055 13.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX66368.1 - 3.8e-07 30.6 0.2 7.8e-07 29.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX66369.1 - 8.2e-43 144.8 0.1 1.5e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Amidase02_C PF12123.8 EAX66370.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX66371.1 - 1.3e-16 60.5 3.6 2.7e-16 59.5 3.6 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66371.1 - 0.028 13.7 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ank PF00023.30 EAX66372.1 - 4.7e-62 203.9 25.6 6.3e-08 32.7 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX66372.1 - 4.2e-61 202.6 14.4 9.1e-09 35.7 0.0 9.3 4 4 5 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66372.1 - 2e-54 182.1 48.5 8.8e-13 48.7 2.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66372.1 - 1.1e-41 140.3 15.5 5.9e-10 39.2 0.2 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66372.1 - 4.9e-36 118.7 16.6 6.7e-05 23.0 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ufm1 PF03671.14 EAX66372.1 - 6.2e-10 39.0 1.8 1.4 9.0 0.0 5.7 2 2 6 8 8 8 3 Ubiquitin fold modifier 1 protein DUF3130 PF11328.8 EAX66372.1 - 0.00012 22.2 15.8 4 7.8 0.1 6.5 1 1 6 8 8 8 3 Protein of unknown function (DUF3130 DUF1214 PF06742.11 EAX66372.1 - 0.00015 22.2 2.2 0.97 9.9 0.0 3.9 2 2 1 3 3 3 1 Protein of unknown function (DUF1214) Cystatin PF00031.21 EAX66372.1 - 0.00035 20.8 12.3 4.6 7.6 0.0 5.2 5 0 0 5 5 5 1 Cystatin domain Membr_traf_MHD PF10540.9 EAX66372.1 - 0.0035 17.5 2.0 69 3.6 0.0 4.4 4 0 0 4 4 4 0 Munc13 (mammalian uncoordinated) homology domain DUF1173 PF06666.11 EAX66372.1 - 0.0044 16.0 3.5 3.1 6.6 0.1 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF1173) Amidinotransf PF02274.17 EAX66372.1 - 0.0091 15.1 6.2 3.7 6.6 0.2 3.1 2 1 1 3 3 3 2 Amidinotransferase PH_8 PF15409.6 EAX66372.1 - 0.069 13.4 0.4 34 4.8 0.0 4.0 2 2 0 4 4 4 0 Pleckstrin homology domain YcxB PF14317.6 EAX66372.1 - 0.081 12.6 0.0 7.5 6.3 0.0 3.8 4 0 0 4 4 4 0 YcxB-like protein DUF1947 PF09183.10 EAX66372.1 - 0.19 12.1 5.0 71 3.8 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Minor_capsid_3 PF12691.7 EAX66372.1 - 0.72 10.2 10.5 65 3.9 0.1 4.6 1 1 4 5 5 5 0 Minor capsid protein from bacteriophage FTP PF07504.13 EAX66372.1 - 2.3 8.1 10.4 1.8e+02 2.0 0.0 5.8 8 0 0 8 8 8 0 Fungalysin/Thermolysin Propeptide Motif SAM_Exu PF18609.1 EAX66372.1 - 9.9 6.3 7.0 1.7e+02 2.4 0.2 4.2 3 0 0 3 3 3 0 Exuperantia SAM-like domain Glyco_hydro_30C PF17189.4 EAX66375.1 - 8e-08 32.4 2.1 1.5e-07 31.5 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EAX66375.1 - 4.4e-05 22.6 0.5 6.5e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain PTR PF12789.7 EAX66376.1 - 2.3e-05 24.3 0.6 2.3e-05 24.3 0.6 4.1 2 1 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX66376.1 - 0.016 14.9 0.3 0.07 12.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX66376.1 - 0.056 13.2 0.2 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX66376.1 - 0.3 10.6 23.8 0.05 13.2 8.2 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Tli4_C PF18426.1 EAX66376.1 - 0.38 11.1 2.2 5 7.4 0.1 2.3 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain MeaB PF03308.16 EAX66376.1 - 0.39 9.7 2.2 0.59 9.1 2.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX66376.1 - 0.52 10.8 0.0 0.52 10.8 0.0 3.1 3 1 1 5 5 5 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX66376.1 - 0.58 9.9 11.6 0.54 10.0 9.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF1433 PF07252.11 EAX66376.1 - 0.7 10.2 4.9 0.95 9.7 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1433) Pox_A32 PF04665.12 EAX66377.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66377.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66377.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66377.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66377.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66377.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66377.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_D5 PF03288.16 EAX66378.1 - 7.3e-05 23.2 1.7 0.00033 21.1 1.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66378.1 - 0.034 14.8 0.1 0.075 13.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66378.1 - 0.072 13.1 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX66379.1 - 0.022 14.8 0.4 0.022 14.8 0.4 3.2 4 0 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX66379.1 - 0.85 9.9 14.9 2.8 8.3 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX66379.1 - 2.2 8.9 6.4 15 6.2 0.1 3.2 3 1 0 3 3 3 0 YmaF family Pox_A32 PF04665.12 EAX66380.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX66380.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX66380.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX66380.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX66381.1 - 3e-39 134.9 4.8 4.3e-39 134.4 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX66382.1 - 0.002 17.8 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX66383.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX66384.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX66389.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66389.1 - 0.062 13.3 0.4 0.092 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX66389.1 - 0.097 12.7 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Meiosis_expr PF15163.6 EAX66392.1 - 0.03 15.0 1.3 0.038 14.7 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX66392.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family Amidase02_C PF12123.8 EAX66393.1 - 0.0048 16.5 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX66393.1 - 0.15 11.9 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PapD_N PF00345.20 EAX66394.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX66394.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX66396.1 - 1.7e-119 397.6 12.0 2.1e-119 397.4 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX66396.1 - 0.017 14.5 0.2 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KELK PF15796.5 EAX66396.1 - 0.05 14.1 1.9 5 7.6 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX66396.1 - 0.18 12.4 1.2 0.33 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) PapD_N PF00345.20 EAX66397.1 - 0.045 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX66397.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Nab1 PF04902.12 EAX66400.1 - 0.022 15.1 0.7 0.027 14.9 0.7 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 PAXIP1_C PF15364.6 EAX66400.1 - 0.066 13.5 1.7 0.089 13.1 1.7 1.3 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4107 PF13389.6 EAX66402.1 - 1.2e-40 139.3 4.0 1.3e-40 139.2 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66402.1 - 0.061 13.7 0.6 0.082 13.3 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta ECH_1 PF00378.20 EAX66404.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ANAPC4_WD40 PF12894.7 EAX66405.1 - 0.0013 19.0 0.0 4.8 7.6 0.0 3.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMtag PF10159.9 EAX66405.1 - 0.23 11.7 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated DUF2897 PF11446.8 EAX66406.1 - 0.88 9.5 3.0 1.4 8.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX66407.1 - 7.5e-146 484.0 13.6 9.3e-146 483.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66407.1 - 0.1 13.1 5.2 2.1 8.9 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX66407.1 - 0.13 12.8 2.6 0.5 10.8 0.1 2.1 2 0 0 2 2 2 0 Fez1 Tho2 PF11262.8 EAX66408.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DNA_pol_B_2 PF03175.13 EAX66411.1 - 2e-22 79.7 4.1 2.6e-22 79.3 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66411.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) FAS_N PF17828.1 EAX66412.1 - 0.0094 16.0 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX66413.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66413.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX66419.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX66421.1 - 1.7e-156 518.9 13.0 2e-156 518.6 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66421.1 - 0.08 13.4 4.0 2.3 8.7 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX66421.1 - 0.8 10.3 3.8 0.6 10.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX66423.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX66424.1 - 2.9e-07 30.2 0.2 6e-07 29.2 0.1 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX66427.1 - 0.032 14.7 0.4 0.061 13.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX66427.1 - 0.87 9.7 4.2 7.8 6.6 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein VirE PF05272.11 EAX66428.1 - 0.0088 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX66428.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX66428.1 - 0.084 11.8 0.2 7.4 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2400 PF09674.10 EAX66430.1 - 0.047 13.7 0.7 0.062 13.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX66431.1 - 6.3e-158 523.5 14.5 7.6e-158 523.2 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX66431.1 - 0.11 12.9 2.2 0.19 12.2 0.4 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX66431.1 - 0.2 11.5 1.4 0.73 9.7 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX66431.1 - 0.69 10.4 8.2 2.2 8.8 0.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX66432.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX66432.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX66436.1 - 2.8e-157 521.4 15.2 3.5e-157 521.1 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX66436.1 - 0.11 12.0 0.1 0.4 10.2 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX66436.1 - 0.94 10.0 7.8 2.3 8.8 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX66438.1 - 0.015 15.3 10.2 0.017 15.1 10.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YmaF PF12788.7 EAX66440.1 - 0.16 12.5 1.5 6.2 7.4 0.1 2.0 1 1 0 1 1 1 0 YmaF family DUF1493 PF07377.12 EAX66441.1 - 0.017 15.5 1.4 0.024 15.1 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX66444.1 - 0.032 14.3 1.7 0.032 14.3 1.7 3.8 5 1 0 5 5 5 0 Phage tail repeat like BRO1 PF03097.18 EAX66444.1 - 0.045 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX66444.1 - 0.8 9.3 6.7 1.3 8.6 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX66445.1 - 0.065 13.7 0.4 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX66445.1 - 0.37 10.9 3.9 6.7 6.8 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX66446.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX66447.1 - 0.052 14.0 0.2 0.089 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX66448.1 - 0.024 15.1 0.8 0.044 14.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX66449.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX66450.1 - 9.6e-18 64.0 2.1 9.6e-18 64.0 2.1 4.3 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX66450.1 - 0.0064 16.1 7.0 0.031 13.9 4.9 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX66450.1 - 8.2 6.9 16.5 11 6.5 0.2 4.2 4 0 0 4 4 4 0 Phage tail fibre repeat Glyco_hydro_98M PF08306.11 EAX66451.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 CENP-B_dimeris PF09026.10 EAX66451.1 - 0.34 11.3 5.5 0.58 10.6 5.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FSAP_sig_propep PF03032.15 EAX66451.1 - 1.4 9.0 8.4 2.2 8.3 8.4 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF3839 PF12943.7 EAX66452.1 - 1.3e-148 493.1 10.1 1.5e-148 492.9 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX66452.1 - 0.12 13.0 0.6 0.77 10.4 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5398) TMP PF05017.14 EAX66453.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66454.1 - 0.081 12.8 0.7 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX66455.1 - 3.3e-52 176.2 5.5 3.7e-52 176.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX66456.1 - 2.1e-05 24.9 2.4 0.0001 22.7 2.4 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66456.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66456.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain TMP PF05017.14 EAX66457.1 - 0.042 14.4 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66458.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX66460.1 - 4.3e-06 27.2 0.1 1e-05 26.0 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX66460.1 - 0.0057 16.5 0.1 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain CD99L2 PF12301.8 EAX66461.1 - 0.056 13.7 1.1 0.077 13.3 0.2 1.7 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF347 PF03988.12 EAX66461.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DNA_pol_B_2 PF03175.13 EAX66462.1 - 2.3e-16 59.7 2.6 2.4e-16 59.7 2.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66462.1 - 0.031 14.6 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX66466.1 - 0.00024 20.6 2.6 0.00037 20.0 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66466.1 - 0.0047 16.6 0.2 0.0062 16.2 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66466.1 - 0.027 14.0 0.1 0.035 13.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66466.1 - 0.036 13.8 0.2 0.2 11.3 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66466.1 - 0.042 13.6 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66466.1 - 0.12 12.4 0.6 1.1 9.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX66466.1 - 0.12 12.8 2.3 0.16 12.4 1.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4107 PF13389.6 EAX66467.1 - 5.9e-67 224.9 2.6 8.5e-67 224.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2400 PF09674.10 EAX66468.1 - 0.034 14.1 0.6 0.045 13.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX66469.1 - 0.027 14.9 0.5 0.034 14.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX66469.1 - 1 8.3 2.9 1.1 8.2 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX66469.1 - 2 8.4 6.0 2.2 8.3 6.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX66470.1 - 0.0054 16.7 0.2 0.0073 16.3 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX66471.1 - 0.045 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66471.1 - 0.05 13.6 0.3 0.076 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX66471.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) T5orf172 PF10544.9 EAX66472.1 - 2.8e-06 27.8 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX66472.1 - 0.011 15.6 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX66472.1 - 0.017 14.7 1.1 0.16 11.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX66473.1 - 6e-40 137.2 4.2 8.2e-40 136.8 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX66474.1 - 0.095 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX66475.1 - 0.06 13.8 2.3 0.082 13.4 2.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX66475.1 - 0.076 12.0 0.1 0.077 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX66477.1 - 5.4e-63 208.9 41.1 1e-31 108.8 13.5 4.7 2 2 3 5 5 4 3 Phage tail repeat like Peptidase_S66 PF02016.15 EAX66477.1 - 0.01 15.9 1.4 44 4.2 0.1 4.4 1 1 3 4 4 4 0 LD-carboxypeptidase N-terminal domain DUF4116 PF13475.6 EAX66477.1 - 0.031 14.0 0.9 0.06 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX66477.1 - 0.11 11.9 3.1 0.38 10.2 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX66477.1 - 0.2 12.0 6.7 22 5.5 0.3 4.4 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain PSP PF04046.16 EAX66478.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MULE PF10551.9 EAX66479.1 - 4.7e-06 26.9 0.0 9.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF2939 PF11159.8 EAX66480.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66480.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX66481.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66481.1 - 0.022 14.8 0.4 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF4107 PF13389.6 EAX66482.1 - 1.9e-71 239.4 3.6 2.9e-71 238.8 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX66484.1 - 0.053 14.0 1.5 0.06 13.8 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX66484.1 - 0.23 11.5 3.4 6.1 7.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF257 PF03192.13 EAX66486.1 - 0.0008 19.3 0.0 0.0009 19.1 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX66486.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p TMP PF05017.14 EAX66489.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX66489.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 EAX66491.1 - 0.3 11.1 5.6 0.37 10.8 5.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Imm70 PF15601.6 EAX66493.1 - 0.019 14.5 9.1 7 6.2 0.2 4.0 1 1 5 6 6 6 0 Immunity protein 70 PapD_N PF00345.20 EAX66494.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66494.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PSP PF04046.16 EAX66495.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Gly_rich PF12810.7 EAX66496.1 - 1.2e-37 130.2 41.5 1.4e-37 130.0 41.5 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3213 PF11491.8 EAX66498.1 - 0.011 15.9 0.6 0.026 14.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) HNH_3 PF13392.6 EAX66499.1 - 2.7e-07 30.2 0.1 4.9e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF5446 PF17522.2 EAX66500.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DNA_pol_B_2 PF03175.13 EAX66501.1 - 2.2e-21 76.3 4.8 2.6e-21 76.0 4.8 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4378 PF14309.6 EAX66502.1 - 0.027 14.9 0.1 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) Amidase02_C PF12123.8 EAX66503.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX66505.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX66506.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX66506.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.13 EAX66507.1 - 1e-11 44.4 0.6 2e-11 43.5 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66507.1 - 0.042 13.1 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX66507.1 - 0.13 12.3 0.3 9.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DNA_pol_B_2 PF03175.13 EAX66509.1 - 1.5e-09 37.2 2.1 2.3e-09 36.7 1.4 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4107 PF13389.6 EAX66510.1 - 4.8e-66 221.9 12.4 2.4e-64 216.4 12.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX66515.1 - 0.084 12.8 9.5 0.11 12.4 9.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX66515.1 - 4.3 4.9 14.7 5.7 4.5 14.7 1.2 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX66515.1 - 7.7 7.0 6.7 12 6.4 6.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4378 PF14309.6 EAX66517.1 - 0.018 15.4 0.1 0.09 13.1 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) DUF4378 PF14309.6 EAX66520.1 - 0.03 14.7 0.1 0.12 12.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX66520.1 - 0.097 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 La domain DASH_Dam1 PF08653.10 EAX66523.1 - 0.055 13.3 0.0 0.81 9.5 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 VirE PF05272.11 EAX66524.1 - 0.024 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.9 EAX66524.1 - 0.075 11.9 0.2 6.9 5.5 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EAX66524.1 - 0.081 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TMP PF05017.14 EAX66525.1 - 0.019 15.4 5.3 11 7.2 0.2 3.5 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX66526.1 - 1.2e-43 149.1 0.8 1.3e-43 148.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66526.1 - 0.13 12.6 0.7 0.16 12.4 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PSP PF04046.16 EAX66529.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66530.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat BRO1 PF03097.18 EAX66532.1 - 0.037 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain KilA-N PF04383.13 EAX66533.1 - 8.2e-16 57.9 0.5 2.5e-15 56.3 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX66533.1 - 0.0029 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF5093 PF17011.5 EAX66534.1 - 0.087 13.1 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) DUF1493 PF07377.12 EAX66535.1 - 0.02 15.3 1.0 0.042 14.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX66538.1 - 4.8e-05 22.9 3.7 8.9e-05 22.1 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66538.1 - 0.0062 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66538.1 - 0.01 15.4 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX66538.1 - 0.055 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4378 PF14309.6 EAX66540.1 - 0.03 14.7 0.0 0.16 12.4 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) MULE PF10551.9 EAX66542.1 - 7.6e-12 45.5 0.1 1.2e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX66542.1 - 0.094 13.0 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 PWI domain DUF2897 PF11446.8 EAX66543.1 - 0.15 12.0 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ank_2 PF12796.7 EAX66544.1 - 7.5e-54 180.3 22.2 5.8e-14 52.4 0.3 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX66544.1 - 1.1e-51 172.6 13.2 1.2e-10 41.7 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX66544.1 - 5.9e-50 165.6 10.7 1.4e-09 37.9 0.1 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAX66544.1 - 5.5e-44 147.6 15.7 9e-12 45.0 0.3 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66544.1 - 8.4e-41 133.3 5.9 6.1e-07 29.3 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat ThiS-like PF14453.6 EAX66544.1 - 3.7e-06 26.9 8.3 2.3 8.3 0.1 5.2 1 1 4 5 5 5 2 ThiS-like ubiquitin LolA PF03548.15 EAX66544.1 - 0.00017 21.4 0.2 0.51 10.0 0.1 2.4 1 1 1 2 2 2 2 Outer membrane lipoprotein carrier protein LolA CEP44 PF15007.6 EAX66544.1 - 0.0025 18.0 0.0 54 4.0 0.0 4.2 2 1 3 5 5 5 0 Centrosomal spindle body, CEP44 PH_8 PF15409.6 EAX66544.1 - 0.0026 18.0 1.5 37 4.7 0.0 4.4 1 1 4 5 5 5 0 Pleckstrin homology domain GPI-anchored PF10342.9 EAX66544.1 - 0.0034 18.1 1.1 2.5 8.9 0.1 3.1 1 1 2 3 3 3 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Phage_G PF02306.15 EAX66544.1 - 0.011 15.5 1.7 7.7 6.2 0.1 3.6 1 1 3 4 4 4 0 Major spike protein (G protein) DUF2149 PF09919.9 EAX66544.1 - 0.045 14.0 5.0 96 3.3 0.0 4.6 1 1 2 5 5 5 0 Uncharacterized conserved protein (DUF2149) SIP PF04954.13 EAX66544.1 - 0.046 14.2 1.2 8 7.0 0.1 2.2 1 1 1 2 2 2 0 Siderophore-interacting protein DUF762 PF05555.11 EAX66544.1 - 0.65 9.5 4.3 8.1 5.9 0.3 3.1 1 1 3 4 4 4 0 Coxiella burnetii protein of unknown function (DUF762) AbrB_C PF18277.1 EAX66544.1 - 0.82 9.4 6.0 2.4e+02 1.5 0.0 4.8 5 0 0 5 5 5 0 AbrB C-terminal domain Ank_4 PF13637.6 EAX66545.1 - 0.016 15.8 0.0 0.048 14.3 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EAX66545.1 - 0.035 14.6 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 EAX66545.1 - 0.079 13.6 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Synaptonemal_3 PF15191.6 EAX66545.1 - 0.09 12.6 3.8 5.3 6.9 0.2 2.9 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 Rab_bind PF16704.5 EAX66545.1 - 0.65 10.1 7.0 11 6.2 0.2 3.1 3 0 0 3 3 3 0 Rab binding domain gp45-slide_C PF09116.10 EAX66545.1 - 2.2 8.4 5.4 63 3.7 0.2 2.9 1 1 2 3 3 3 0 gp45 sliding clamp, C terminal SH3BGR PF04908.15 EAX66546.1 - 0.098 12.8 0.8 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF4108 PF13390.6 EAX66547.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX66548.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Herpes_UL25 PF01499.16 EAX66549.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family tRNA_synt_1c_R1 PF04558.15 EAX66550.1 - 0.0038 17.2 1.5 0.0066 16.5 0.1 1.9 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66550.1 - 0.0061 16.1 0.2 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX66550.1 - 0.029 13.6 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4108 PF13390.6 EAX66552.1 - 1.7e-50 170.7 5.2 1.9e-50 170.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX66553.1 - 2.2e-05 24.9 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66553.1 - 0.057 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DASH_Dam1 PF08653.10 EAX66554.1 - 0.12 12.1 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Trypan_PARP PF05887.11 EAX66556.1 - 0.3 11.1 10.6 0.32 11.0 10.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX66556.1 - 4.8 7.6 6.1 5.5 7.4 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Spo12 PF05032.12 EAX66557.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX66558.1 - 3.5e-06 27.5 0.1 7.7e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX66558.1 - 0.0034 17.2 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX66559.1 - 1.5e-22 80.2 3.2 1.8e-22 79.9 3.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX66560.1 - 0.00014 21.4 3.9 0.00025 20.6 3.9 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66560.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66560.1 - 0.0097 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX66560.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAX66561.1 - 2.6e-158 524.8 11.9 3.2e-158 524.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX66561.1 - 0.093 13.2 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX66561.1 - 0.15 12.6 6.4 1.9 9.0 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX66561.1 - 3.2 8.1 6.6 11 6.4 0.1 3.6 4 2 0 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX66562.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_D5 PF03288.16 EAX66563.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66563.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66563.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX66564.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX66565.1 - 0.045 13.6 2.1 0.065 13.1 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GGDEF PF00990.21 EAX66565.1 - 0.071 12.9 0.0 0.071 12.9 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_D5 PF03288.16 EAX66566.1 - 0.00012 22.5 2.3 0.00071 20.0 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX66566.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX66567.1 - 1.3e-154 512.6 14.0 1.5e-154 512.4 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX66567.1 - 0.99 9.8 3.4 0.92 9.9 1.3 2.0 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF846 PF05832.12 EAX66568.1 - 0.054 13.5 0.1 0.14 12.2 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) IstB_IS21 PF01695.17 EAX66570.1 - 2.1e-05 24.3 0.3 0.28 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX66570.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX66570.1 - 3.8e-05 23.3 2.0 3.8e-05 23.3 2.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX66570.1 - 0.00038 20.5 5.0 0.00069 19.7 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66570.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66570.1 - 0.0027 17.5 1.5 0.0061 16.4 0.9 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66570.1 - 0.0039 16.9 2.5 0.009 15.7 0.2 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66570.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX66570.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX66570.1 - 0.07 13.6 0.1 0.72 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66570.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66570.1 - 0.52 10.6 4.8 8.1 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX66570.1 - 1.7 9.4 11.0 0.14 12.8 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Spo0A_C PF08769.11 EAX66571.1 - 0.1 12.7 0.2 0.21 11.7 0.2 1.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PapD_N PF00345.20 EAX66573.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_N PF00345.20 EAX66574.1 - 0.057 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66574.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX66576.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX66577.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66578.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Tctex-1 PF03645.13 EAX66579.1 - 0.12 12.6 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Tctex-1 family Mid2 PF04478.12 EAX66580.1 - 0.0005 19.9 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX66580.1 - 0.00064 19.4 2.0 0.0011 18.7 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX66580.1 - 0.00085 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX66580.1 - 0.0024 18.1 0.6 0.059 13.7 0.3 2.3 2 1 0 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 EAX66580.1 - 0.0041 17.0 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX66580.1 - 0.0054 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX66580.1 - 0.0069 16.6 0.7 0.011 15.9 0.7 1.5 1 1 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 EAX66580.1 - 0.029 14.1 0.1 0.043 13.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX66580.1 - 0.034 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 EAX66580.1 - 0.052 14.4 0.1 0.17 12.8 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 EAX66580.1 - 0.052 11.9 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 EAX66580.1 - 0.058 12.8 3.5 0.099 12.0 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PTP_tm PF18861.1 EAX66580.1 - 0.083 12.9 0.9 0.21 11.6 0.3 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MMM1 PF10296.9 EAX66580.1 - 0.088 11.8 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ABC2_membrane_3 PF12698.7 EAX66580.1 - 0.096 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5385 PF17359.2 EAX66580.1 - 0.11 12.0 0.7 1.3 8.5 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) SKG6 PF08693.10 EAX66580.1 - 0.11 11.9 4.0 0.2 11.1 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gemini_mov PF01708.16 EAX66580.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Otopetrin PF03189.13 EAX66580.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Otopetrin TMP PF05017.14 EAX66582.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX66583.1 - 2.8e-96 323.3 4.8 2.8e-96 323.3 4.8 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX66583.1 - 0.11 12.0 0.5 0.2 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX66583.1 - 0.18 11.8 1.0 0.57 10.2 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FapA PF03961.13 EAX66583.1 - 0.2 10.2 4.4 0.28 9.7 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Trypan_PARP PF05887.11 EAX66584.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WASH-7_C PF14746.6 EAX66585.1 - 0.036 13.7 1.1 0.066 12.9 1.1 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX66585.1 - 0.2 11.9 5.6 0.47 10.7 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX66585.1 - 0.27 11.0 5.1 0.38 10.5 5.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTR PF12789.7 EAX66586.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.4 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX66586.1 - 0.093 12.9 12.8 3.3 8.1 0.3 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4795 PF16043.5 EAX66586.1 - 0.18 11.4 3.7 0.95 9.0 3.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX66586.1 - 0.85 10.2 4.7 19 5.9 0.2 3.1 2 1 0 2 2 2 0 YmaF family FAD_binding_6 PF00970.24 EAX66589.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF4108 PF13390.6 EAX66590.1 - 6.1e-62 207.8 8.5 6.8e-62 207.6 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX66592.1 - 9.4e-93 311.7 4.4 1.1e-92 311.5 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) TrfA PF07042.11 EAX66592.1 - 0.061 12.4 0.1 7.6 5.5 0.0 2.1 2 0 0 2 2 2 0 TrfA protein Trypan_PARP PF05887.11 EAX66593.1 - 0.28 11.2 6.4 0.39 10.7 6.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2897 PF11446.8 EAX66593.1 - 1.1 9.2 3.0 2 8.3 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX66594.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX66595.1 - 0.011 15.3 1.6 0.028 14.0 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX66595.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.4 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX66595.1 - 0.085 13.0 12.8 3.3 8.1 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX66595.1 - 0.76 10.3 5.5 17 6.1 0.1 3.2 3 1 0 3 3 3 0 YmaF family PTR PF12789.7 EAX66596.1 - 1.1e-38 131.1 28.9 1.4e-32 111.5 13.9 4.3 2 2 1 3 3 3 2 Phage tail repeat like MetOD2 PF18548.1 EAX66597.1 - 0.019 15.0 14.1 0.049 13.8 0.5 3.4 2 1 1 3 3 3 0 Metanogen output domain 2 Exonuc_VII_L PF02601.15 EAX66597.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAX66597.1 - 0.12 11.2 20.6 0.18 10.7 1.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NurA PF09376.10 EAX66597.1 - 0.34 10.6 4.3 0.59 9.8 0.1 2.1 1 1 1 2 2 2 0 NurA domain DivIVA PF05103.13 EAX66597.1 - 0.8 9.8 9.9 0.15 12.1 5.1 2.1 2 0 0 2 2 2 0 DivIVA protein Fez1 PF06818.15 EAX66597.1 - 1.6 9.1 23.5 0.73 10.3 7.1 2.3 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 EAX66597.1 - 1.7 8.7 11.3 1.5 8.8 6.7 2.5 2 1 0 2 2 2 0 Laminin Domain II Prominin PF05478.11 EAX66597.1 - 3.8 5.3 6.9 0.28 9.1 0.3 1.9 2 1 1 3 3 3 0 Prominin HR1 PF02185.16 EAX66597.1 - 4 7.6 15.8 0.62 10.2 8.5 3.2 3 1 0 3 3 3 0 Hr1 repeat PapD_N PF00345.20 EAX66598.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DHR-2 PF06920.13 EAX66600.1 - 0.0018 17.0 0.7 0.002 16.9 0.7 1.0 1 0 0 1 1 1 1 Dock homology region 2 FDX-ACB PF03147.14 EAX66600.1 - 0.033 14.6 0.5 0.045 14.2 0.5 1.3 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain DUF4108 PF13390.6 EAX66601.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) JMY PF15871.5 EAX66603.1 - 0.033 13.5 0.3 0.052 12.8 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4795 PF16043.5 EAX66604.1 - 0.45 10.1 2.0 2.4 7.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX66605.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66605.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX66605.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66605.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) TMP PF05017.14 EAX66606.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX66609.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3417 PF11897.8 EAX66610.1 - 0.11 13.0 0.5 0.13 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DNA_pol_B_2 PF03175.13 EAX66612.1 - 8.6e-09 34.8 1.5 1.5e-08 34.0 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX66612.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX66612.1 - 0.12 12.4 0.0 0.83 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor MULE PF10551.9 EAX66613.1 - 5.7e-05 23.5 1.9 7.4e-05 23.1 0.5 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX66613.1 - 0.0069 15.3 0.1 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family DNA_pol_B_2 PF03175.13 EAX66614.1 - 3e-09 36.3 1.0 4.5e-09 35.7 1.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66614.1 - 0.093 12.7 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PTR PF12789.7 EAX66615.1 - 2.5e-68 226.0 57.8 2.5e-32 110.7 18.4 5.3 2 2 2 4 4 4 3 Phage tail repeat like RACo_linker PF17650.1 EAX66615.1 - 0.0018 18.1 0.3 0.48 10.3 0.1 3.3 2 1 1 3 3 3 1 RACo linker region Apolipoprotein PF01442.18 EAX66615.1 - 0.011 15.7 4.1 0.016 15.1 4.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Peptidase_C78 PF07910.13 EAX66615.1 - 0.02 14.4 2.9 1.6 8.1 0.2 3.1 1 1 3 4 4 4 0 Peptidase family C78 PH_TFIIH PF08567.11 EAX66615.1 - 0.061 13.7 10.6 1.6 9.1 0.3 4.7 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain GUN4_N PF16416.5 EAX66615.1 - 0.13 12.3 4.4 6.2 6.9 0.2 3.5 1 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal AviRa PF11599.8 EAX66615.1 - 0.23 10.9 5.8 0.4 10.1 1.3 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Neugrin PF06413.11 EAX66615.1 - 8.7 6.3 8.8 9.8 6.1 7.6 1.7 1 1 0 1 1 1 0 Neugrin PapD_N PF00345.20 EAX66616.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66616.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX66617.1 - 3.6e-08 32.7 1.1 5.5e-08 32.1 0.8 1.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66617.1 - 0.098 12.7 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX66618.1 - 1.2e-38 133.0 4.8 1.6e-38 132.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX66620.1 - 5.9e-25 87.3 1.0 1e-24 86.5 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX66620.1 - 0.02 15.5 0.0 0.052 14.2 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_D5 PF03288.16 EAX66622.1 - 1.9e-05 25.0 2.9 0.00012 22.5 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66622.1 - 0.081 13.6 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Trypan_PARP PF05887.11 EAX66623.1 - 0.048 13.6 8.1 0.075 13.0 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX66624.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX66625.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX66626.1 - 0.046 14.2 0.2 0.089 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ResIII PF04851.15 EAX66627.1 - 0.00038 20.5 2.9 0.00079 19.5 2.9 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66627.1 - 0.00069 19.4 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX66627.1 - 0.005 17.1 0.0 0.0081 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX66627.1 - 0.014 15.2 1.4 0.046 13.5 1.4 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX66627.1 - 0.067 12.6 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66627.1 - 0.09 13.0 4.4 2.4 8.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_19 PF13245.6 EAX66627.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain PapD_N PF00345.20 EAX66631.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66631.1 - 0.031 14.3 0.5 0.042 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX66632.1 - 0.012 16.0 0.4 0.017 15.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66632.1 - 2.6 8.1 4.8 2.8 8.0 4.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1731 PF08338.11 EAX66633.1 - 0.23 11.3 0.1 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) ACDC PF14733.6 EAX66634.1 - 0.045 14.1 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 AP2-coincident C-terminal PTR PF12789.7 EAX66635.1 - 1.2e-16 60.5 1.3 1.2e-16 60.5 1.3 3.6 3 1 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX66635.1 - 0.0091 15.6 2.9 0.011 15.4 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) Pox_D5 PF03288.16 EAX66636.1 - 7.3e-05 23.2 4.3 0.00057 20.3 4.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66636.1 - 0.018 15.6 0.1 0.034 14.8 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66636.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX66637.1 - 3.1e-37 126.4 33.0 2.8e-33 113.8 16.7 4.5 3 1 1 4 4 4 3 Phage tail repeat like DUF2785 PF10978.8 EAX66637.1 - 0.0071 16.1 0.9 0.014 15.2 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2785) DUF4795 PF16043.5 EAX66637.1 - 0.087 12.4 7.9 8.2 6.0 7.9 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX66637.1 - 0.89 9.9 5.2 23 5.4 0.1 3.5 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF4107 PF13389.6 EAX66644.1 - 1.2e-43 149.1 1.8 1.3e-43 148.9 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66644.1 - 0.076 13.4 0.8 0.087 13.2 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX66645.1 - 1.7e-10 40.4 3.0 1.4e-09 37.4 2.3 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66645.1 - 0.097 12.9 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX66645.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4108 PF13390.6 EAX66646.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX66649.1 - 0.0037 16.9 0.1 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX66650.1 - 0.00012 21.6 0.3 0.00014 21.4 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Mo-nitro_C PF06967.11 EAX66651.1 - 0.75 9.8 7.6 2.8 8.0 2.5 2.1 1 1 1 2 2 2 0 Mo-dependent nitrogenase C-terminus DUF4108 PF13390.6 EAX66652.1 - 2e-72 241.8 11.6 2.3e-72 241.6 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX66654.1 - 3.3e-58 195.7 4.5 3.7e-58 195.5 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX66654.1 - 0.1 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PSP PF04046.16 EAX66656.1 - 0.07 13.0 0.5 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX66658.1 - 5.4e-18 64.9 1.7 6.9e-18 64.5 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX66658.1 - 0.0025 18.0 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF4106 PF13388.6 EAX66659.1 - 2.7e-08 33.5 8.2 3.2e-08 33.3 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX66660.1 - 4.4e-06 26.4 2.2 4.4e-06 26.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66660.1 - 2.3e-05 24.7 0.2 0.00018 21.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66660.1 - 3.4e-05 23.7 0.3 0.3 10.8 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66660.1 - 0.00014 21.9 3.2 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66660.1 - 0.00046 20.0 0.1 0.00086 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66660.1 - 0.0014 18.5 0.6 0.0033 17.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66660.1 - 0.0017 18.1 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66660.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX66660.1 - 0.059 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX66660.1 - 0.061 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX66660.1 - 0.075 13.5 0.1 0.64 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66660.1 - 0.082 12.4 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX66660.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX66660.1 - 0.43 10.9 4.5 9.4 6.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX66662.1 - 7.9e-43 146.4 1.2 9.2e-43 146.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66662.1 - 0.083 13.3 0.6 0.11 12.9 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX66664.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX66667.1 - 1.9e-41 140.4 0.6 3.7e-41 139.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX66669.1 - 2.5e-33 113.9 19.2 6e-32 109.5 13.5 4.6 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX66669.1 - 0.018 14.8 1.1 0.038 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Ank_4 PF13637.6 EAX66672.1 - 5.9e-34 116.0 3.3 4.8e-10 39.8 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66672.1 - 1e-33 115.8 1.1 2e-13 50.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66672.1 - 1e-30 105.4 0.2 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66672.1 - 5.3e-26 87.8 0.9 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX66672.1 - 1.1e-21 76.3 5.2 0.00026 21.3 0.0 6.7 6 1 1 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX66672.1 - 0.0025 17.7 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX66672.1 - 0.063 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase TMP PF05017.14 EAX66673.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Cas_Csm6 PF09659.10 EAX66674.1 - 0.0045 15.8 0.1 0.0066 15.3 0.1 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) DUF4795 PF16043.5 EAX66674.1 - 0.0072 15.9 11.3 0.14 11.7 2.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF2939 PF11159.8 EAX66675.1 - 0.0093 16.4 0.4 0.011 16.1 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66675.1 - 4.1 7.4 5.7 4.3 7.3 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX66677.1 - 1.6e-08 34.4 1.1 1.6e-08 34.4 1.1 4.7 5 2 1 6 6 6 2 Phage tail repeat like BRO1 PF03097.18 EAX66677.1 - 0.054 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX66677.1 - 0.68 9.5 11.6 0.44 10.1 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX66678.1 - 2.8e-07 30.3 2.9 4.1e-07 29.7 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66678.1 - 0.0043 16.7 0.2 0.0055 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66678.1 - 0.044 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66678.1 - 0.052 13.3 0.2 0.39 10.4 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66678.1 - 0.057 13.2 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66678.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66678.1 - 0.57 10.4 8.7 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PapD_N PF00345.20 EAX66680.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain VirE PF05272.11 EAX66681.1 - 1e-05 25.3 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX66681.1 - 0.059 13.8 0.4 0.2 12.1 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF3221 PF11518.8 EAX66683.1 - 0.016 15.6 0.8 0.043 14.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DUF4106 PF13388.6 EAX66684.1 - 1.6e-119 399.9 4.6 1.6e-119 399.9 4.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX66684.1 - 0.0032 17.7 0.2 0.3 11.4 0.2 2.5 2 1 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX66684.1 - 0.065 13.8 0.7 0.16 12.6 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX66684.1 - 0.27 11.6 9.1 3.3 8.1 0.4 3.8 4 0 0 4 4 4 0 WYL domain PSP PF04046.16 EAX66687.1 - 0.054 13.4 0.6 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX66688.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DDE_Tnp_4 PF13359.6 EAX66689.1 - 1.5e-36 125.5 0.0 2e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX66689.1 - 8e-08 32.2 0.7 1.5e-06 28.0 0.7 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX66689.1 - 3.5e-05 23.4 0.8 0.0012 18.6 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 EAX66689.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 Transposase DDE domain Pox_D5 PF03288.16 EAX66690.1 - 5.4e-05 23.6 3.4 0.0004 20.8 3.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66690.1 - 0.027 15.1 0.2 0.053 14.1 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX66691.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX66692.1 - 2.2e-156 518.5 13.3 2.7e-156 518.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX66692.1 - 0.1 13.0 0.3 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX66692.1 - 0.15 12.6 7.2 2.3 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX66694.1 - 0.068 13.6 0.5 0.14 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX66695.1 - 1.5e-22 80.1 4.4 1.9e-22 79.8 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66695.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX66697.1 - 3.5e-21 75.0 6.9 3.5e-21 75.0 6.9 3.2 3 1 0 3 3 3 1 Phage tail repeat like DUF5448 PF17526.2 EAX66697.1 - 0.071 13.3 3.1 0.17 12.1 0.4 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5448) DUF4108 PF13390.6 EAX66698.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX66699.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66699.1 - 0.075 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX66703.1 - 2.7e-62 208.9 6.7 3e-62 208.8 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF257 PF03192.13 EAX66704.1 - 0.0044 16.8 0.0 0.0051 16.6 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 DUF4108 PF13390.6 EAX66706.1 - 2.1e-53 180.1 6.9 2.3e-53 180.0 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX66707.1 - 0.00012 22.5 3.0 0.0009 19.7 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66707.1 - 0.054 14.1 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX66707.1 - 0.1 12.6 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3781 PF12636.7 EAX66708.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HTH_11 PF08279.12 EAX66709.1 - 0.13 12.3 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 HTH domain DNA_pol_B_2 PF03175.13 EAX66713.1 - 1.1e-08 34.5 1.0 1.7e-08 33.8 0.9 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66713.1 - 0.099 12.6 0.0 0.72 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF2939 PF11159.8 EAX66714.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66714.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX66715.1 - 2.9e-61 206.3 12.2 9.7e-60 201.4 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66715.1 - 0.12 12.7 0.4 0.18 12.2 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF2939 PF11159.8 EAX66716.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66716.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX66717.1 - 0.01 15.8 0.3 0.015 15.3 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX66718.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX66719.1 - 3e-88 295.4 6.9 3.6e-88 295.1 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX66720.1 - 0.00069 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX66720.1 - 0.15 11.9 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX66721.1 - 4.7e-54 182.9 1.2 6.2e-54 182.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66721.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX66722.1 - 3e-05 23.6 3.1 3.4e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66722.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX66722.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX66722.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PSP PF04046.16 EAX66725.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX66726.1 - 7.3e-07 28.9 2.4 7.3e-07 28.9 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66726.1 - 2.7e-05 24.5 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66726.1 - 6.5e-05 22.7 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66726.1 - 0.00016 21.8 3.3 0.00035 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66726.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66726.1 - 0.0012 18.7 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66726.1 - 0.0018 18.0 0.4 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66726.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX66726.1 - 0.065 12.7 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX66726.1 - 0.067 12.8 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX66726.1 - 0.082 13.3 0.1 0.71 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66726.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66726.1 - 0.31 11.3 4.1 7.6 6.9 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX66728.1 - 0.0024 17.5 0.0 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Trypan_PARP PF05887.11 EAX66729.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nucleopor_Nup85 PF07575.13 EAX66731.1 - 0.0065 15.1 0.0 0.0083 14.8 0.0 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF4108 PF13390.6 EAX66732.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX66735.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66735.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66735.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66735.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66735.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66735.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66735.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX66736.1 - 0.0089 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX66737.1 - 0.01 15.9 0.4 0.015 15.3 0.4 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX66738.1 - 2.4e-05 24.3 0.3 2.4e-05 24.3 0.3 2.9 3 0 0 3 3 3 1 Phage tail repeat like DNA_pol_B_2 PF03175.13 EAX66739.1 - 1.5e-22 80.1 4.4 1.9e-22 79.8 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66739.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) MULE PF10551.9 EAX66741.1 - 1.4e-11 44.6 0.1 2.6e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX66741.1 - 0.14 12.5 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 PWI domain ARGLU PF15346.6 EAX66742.1 - 0.016 15.1 15.5 0.023 14.6 15.5 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GGDEF PF00990.21 EAX66742.1 - 0.025 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX66742.1 - 0.22 11.8 14.5 0.29 11.4 14.5 1.3 1 1 0 1 1 1 0 PcfK-like protein Glyco_hydro_30 PF02055.16 EAX66743.1 - 1.5e-37 129.4 0.4 2e-37 129.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX66743.1 - 2.3e-09 36.9 0.0 3.9e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAX66743.1 - 4e-05 23.4 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 TMP PF05017.14 EAX66744.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX66746.1 - 3.2e-18 65.8 3.5 4e-18 65.5 3.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX66747.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66747.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66747.1 - 5.7e-05 22.9 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66747.1 - 0.00013 22.1 2.8 0.0003 20.8 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66747.1 - 0.00064 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66747.1 - 0.0012 18.6 0.6 0.0023 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66747.1 - 0.0019 17.9 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66747.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX66747.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX66747.1 - 0.088 13.2 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66747.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66747.1 - 0.4 11.0 4.0 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX66748.1 - 1e-05 26.0 0.2 3.3e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX66748.1 - 0.0024 17.5 0.4 0.33 10.5 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain GPS2_interact PF15784.5 EAX66750.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4108 PF13390.6 EAX66751.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX66752.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Ly49 PF08391.10 EAX66752.1 - 0.53 10.7 3.3 0.62 10.4 3.3 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX66752.1 - 0.81 9.6 3.7 1.4 8.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX66753.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX66753.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Amidase02_C PF12123.8 EAX66754.1 - 0.0087 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX66756.1 - 3.8e-07 29.8 1.4 6.8e-07 29.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX66757.1 - 1.9e-16 59.9 2.5 1.9e-16 59.9 2.5 4.5 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX66757.1 - 0.026 14.1 8.0 0.042 13.5 5.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX66757.1 - 0.28 11.7 1.7 0.8 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3839 PF12943.7 EAX66758.1 - 8e-128 425.0 7.0 9.1e-128 424.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX66758.1 - 0.065 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX66758.1 - 0.28 11.7 2.0 1.2 9.7 1.0 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX66758.1 - 0.45 10.8 3.0 1.5 9.2 0.1 2.7 2 1 1 3 3 3 0 Rx N-terminal domain PapD_N PF00345.20 EAX66759.1 - 0.022 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX66760.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Gly-zipper_Omp PF13488.6 EAX66761.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX66761.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX66761.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX66761.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX66762.1 - 5.6e-06 26.3 1.1 5.6e-06 26.3 1.1 3.5 4 2 1 5 5 5 1 Phage tail repeat like DUF2120 PF09893.9 EAX66762.1 - 0.082 13.0 3.2 2.7 8.1 0.5 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4795 PF16043.5 EAX66762.1 - 0.38 10.3 15.8 1.1 8.9 7.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX66763.1 - 1.2e-44 150.2 36.9 2.3e-23 82.0 6.5 5.3 5 2 1 6 6 5 3 Phage tail repeat like DUF5327 PF17261.2 EAX66763.1 - 0.0063 17.2 1.3 5 7.9 0.1 3.1 3 0 0 3 3 3 2 Family of unknown function (DUF5327) DUF4116 PF13475.6 EAX66763.1 - 0.021 14.6 0.2 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Peptidase_C78 PF07910.13 EAX66763.1 - 0.076 12.5 0.8 17 4.8 0.0 2.8 2 1 1 3 3 3 0 Peptidase family C78 pP_pnuc_1 PF18165.1 EAX66763.1 - 0.93 9.4 7.7 3.5 7.5 1.8 2.4 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease MAJIN PF15077.6 EAX66763.1 - 1 9.1 6.0 0.32 10.7 1.7 2.0 2 0 0 2 2 2 0 Membrane-anchored junction protein CppA_C PF14507.6 EAX66763.1 - 1.5 9.5 5.0 29 5.5 0.1 3.7 3 0 0 3 3 3 0 CppA C-terminal Amidase02_C PF12123.8 EAX66767.1 - 0.011 15.5 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase HD_2 PF12917.7 EAX66768.1 - 0.091 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF4106 PF13388.6 EAX66769.1 - 3e-165 550.5 22.4 1.3e-164 548.4 22.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX66770.1 - 3.2e-158 524.5 14.3 4.1e-158 524.1 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX66770.1 - 0.083 13.2 0.9 2.5 8.4 0.0 3.4 3 1 0 4 4 4 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX66770.1 - 0.13 12.1 1.3 0.45 10.4 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX66770.1 - 0.14 12.7 6.5 0.66 10.5 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1935 PF09149.10 EAX66771.1 - 0.0041 17.5 1.3 0.005 17.2 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Fucose_iso_C PF02952.17 EAX66771.1 - 0.041 13.6 0.4 0.079 12.7 0.2 1.5 1 1 1 2 2 2 0 L-fucose isomerase, C-terminal domain MlaD PF02470.20 EAX66771.1 - 0.074 13.4 4.2 0.8 10.0 0.8 2.3 1 1 1 2 2 2 0 MlaD protein ETF PF01012.21 EAX66771.1 - 0.1 12.4 4.1 0.13 12.1 4.1 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein domain KH_4 PF13083.6 EAX66771.1 - 0.15 11.9 1.3 1.9 8.4 0.1 2.2 1 1 1 2 2 2 0 KH domain DUF5077 PF16871.5 EAX66771.1 - 0.27 11.1 5.7 0.45 10.4 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) DUF4058 PF13267.6 EAX66771.1 - 0.56 9.6 7.9 0.61 9.4 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) MerB PF03243.15 EAX66771.1 - 4.6 7.4 7.9 2.1 8.5 3.8 1.9 1 1 1 2 2 2 0 Alkylmercury lyase DUF1493 PF07377.12 EAX66772.1 - 0.037 14.5 0.2 0.08 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX66773.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX66775.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66776.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP IKKbetaNEMObind PF12179.8 EAX66777.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain TMP PF05017.14 EAX66778.1 - 0.28 11.9 8.7 6.3 7.9 0.8 3.3 3 1 1 4 4 4 0 TMP repeat Trypan_PARP PF05887.11 EAX66778.1 - 6.9 6.7 8.7 7.6 6.5 8.7 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX66779.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Adeno_E3_CR2 PF02439.15 EAX66780.1 - 0.0012 18.6 1.9 0.0022 17.7 1.9 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 EAX66780.1 - 0.0019 18.4 2.8 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycophorin A Podoplanin PF05808.11 EAX66780.1 - 0.0019 18.3 3.4 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 1 Podoplanin Mid2 PF04478.12 EAX66780.1 - 0.0022 17.9 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Orf78 PF06024.12 EAX66780.1 - 0.0031 17.8 0.1 0.16 12.3 0.0 2.8 3 0 0 3 3 3 1 Orf78 (ac78) Syndecan PF01034.20 EAX66780.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EAX66780.1 - 0.014 15.3 6.2 0.016 15.1 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family ECSCR PF15820.5 EAX66780.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PsbW PF07123.12 EAX66780.1 - 0.11 12.5 0.7 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) MtrF PF09472.10 EAX66780.1 - 0.11 11.9 3.5 0.21 11.0 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 EAX66780.1 - 0.12 13.2 0.2 0.39 11.6 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 EAX66780.1 - 0.14 11.2 2.0 0.33 9.9 0.1 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Chordopox_G3 PF06129.12 EAX66780.1 - 0.48 11.2 2.2 3.8 8.2 0.2 2.5 3 0 0 3 3 2 0 Chordopoxvirus G3 protein DUF4330 PF14221.6 EAX66780.1 - 1.2 9.3 7.4 4.2 7.6 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) PTP_tm PF18861.1 EAX66780.1 - 2 8.4 5.3 0.51 10.3 0.4 2.4 2 1 1 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF1493 PF07377.12 EAX66781.1 - 0.09 13.2 0.6 0.23 11.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX66782.1 - 5.7e-58 192.8 40.9 7.6e-33 112.4 18.4 4.5 2 2 1 3 3 3 2 Phage tail repeat like Peptidase_C78 PF07910.13 EAX66782.1 - 0.044 13.2 1.7 1.7 8.1 0.3 2.6 1 1 2 3 3 3 0 Peptidase family C78 AviRa PF11599.8 EAX66782.1 - 0.17 11.3 3.1 0.32 10.4 1.3 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX66782.1 - 0.2 12.0 6.8 8.5 6.8 0.2 4.0 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain GUN4_N PF16416.5 EAX66782.1 - 0.23 11.5 1.9 9.5 6.3 0.2 2.9 1 1 1 3 3 3 0 ARM-like repeat domain, GUN4-N terminal Chromo PF00385.24 EAX66783.1 - 0.084 12.8 7.2 0.042 13.8 4.6 1.9 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain MgsA_C PF12002.8 EAX66783.1 - 0.12 12.4 0.4 0.13 12.1 0.4 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF4107 PF13389.6 EAX66784.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX66786.1 - 1.5e-80 270.2 10.5 2e-80 269.8 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX66787.1 - 5.6e-66 221.7 1.9 7.3e-66 221.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX66788.1 - 0.11 12.5 8.6 0.17 11.9 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX66788.1 - 2.2 8.7 6.3 3.1 8.2 6.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MULE PF10551.9 EAX66792.1 - 3.5e-11 43.4 1.6 5.1e-11 42.8 1.6 1.2 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX66792.1 - 0.00072 19.6 1.1 0.0018 18.3 1.1 1.6 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma DNA_pol_B_2 PF03175.13 EAX66795.1 - 4.3e-11 42.3 3.5 2.6e-10 39.8 3.5 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_22 PF13401.6 EAX66798.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX66798.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66798.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66798.1 - 0.00089 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66798.1 - 0.0026 17.5 0.2 0.27 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX66798.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX66798.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX66798.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX66798.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX66798.1 - 0.25 11.6 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX66799.1 - 6.6e-105 349.9 8.0 7.7e-105 349.7 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX66799.1 - 0.028 13.9 0.6 0.037 13.5 0.5 1.2 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX66799.1 - 0.53 10.9 3.3 1.2 9.8 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) FLYWCH PF04500.16 EAX66801.1 - 0.048 13.8 4.7 0.096 12.8 4.7 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain PapD_N PF00345.20 EAX66805.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX66807.1 - 6.8e-148 490.7 10.8 7.9e-148 490.5 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX66807.1 - 0.069 13.4 0.3 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX66807.1 - 0.1 12.4 0.6 0.35 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX66807.1 - 0.5 10.9 3.9 3.1 8.3 0.5 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HD_2 PF12917.7 EAX66808.1 - 0.09 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Trypan_PARP PF05887.11 EAX66809.1 - 0.0052 16.8 8.7 0.0081 16.1 8.7 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX66810.1 - 1.8e-121 404.1 13.3 2.3e-121 403.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX66810.1 - 0.036 14.5 3.0 1.8 9.0 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX66810.1 - 0.097 12.2 0.6 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX66810.1 - 0.2 11.5 1.7 0.59 10.0 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DNA_pol_B_2 PF03175.13 EAX66811.1 - 3.9e-10 39.2 1.8 7.3e-10 38.3 1.8 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66811.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX66812.1 - 1e-21 77.4 4.7 1.3e-21 77.0 4.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral LRR_5 PF13306.6 EAX66813.1 - 8e-20 71.1 4.7 1.5e-11 44.4 0.5 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX66813.1 - 1.8e-12 46.8 3.2 3.9e-06 26.5 0.2 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EAX66813.1 - 0.025 15.0 0.6 0.19 12.2 0.1 2.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) VIGSSK PF14773.6 EAX66814.1 - 0.19 11.8 1.8 14 5.9 0.2 2.2 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal TPR_MLP1_2 PF07926.12 EAX66815.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX66815.1 - 0.043 13.6 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX66815.1 - 0.36 10.8 7.7 0.16 11.9 2.9 2.3 3 0 0 3 3 3 0 Spo12 family MG2 PF01835.19 EAX66818.1 - 9.7e-05 22.8 0.1 0.033 14.6 0.0 2.3 2 0 0 2 2 2 2 MG2 domain DUF4625 PF15418.6 EAX66818.1 - 0.00016 21.9 0.2 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4625) Cohesin PF00963.18 EAX66818.1 - 0.0004 20.6 0.4 0.0004 20.6 0.4 1.9 2 1 0 2 2 2 1 Cohesin domain NPCBM_assoc PF10633.9 EAX66818.1 - 0.0051 17.0 1.8 0.042 14.1 0.2 2.8 3 1 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase ChitinaseA_N PF08329.10 EAX66818.1 - 0.0064 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Chitinase A, N-terminal domain He_PIG PF05345.12 EAX66818.1 - 0.016 15.3 1.8 0.16 12.2 0.1 2.7 3 0 0 3 3 3 0 Putative Ig domain DUF4469 PF14734.6 EAX66818.1 - 0.04 14.1 0.5 0.73 10.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold Lipocalin PF00061.23 EAX66818.1 - 0.044 14.0 1.6 0.053 13.7 0.2 1.7 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family bMG6 PF17962.1 EAX66818.1 - 0.074 13.2 0.2 5.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 PKD PF00801.20 EAX66818.1 - 0.1 12.4 0.3 0.36 10.7 0.1 2.1 2 1 0 2 2 2 0 PKD domain YmaF PF12788.7 EAX66819.1 - 0.062 13.8 1.8 3 8.4 0.1 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX66819.1 - 0.36 11.1 7.6 0.93 9.8 0.3 2.8 3 0 0 3 3 3 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX66820.1 - 9.7e-12 44.5 0.6 1.9e-11 43.6 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66820.1 - 0.039 13.3 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX66820.1 - 0.12 12.4 0.3 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type ARA70 PF12489.8 EAX66821.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3839 PF12943.7 EAX66822.1 - 1.4e-80 270.2 10.1 2e-80 269.8 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX66822.1 - 0.09 13.1 0.2 0.16 12.3 0.1 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 DUF2408 PF10303.9 EAX66822.1 - 0.094 13.3 0.3 0.15 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX66822.1 - 0.11 12.4 1.4 0.36 10.7 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Trypan_PARP PF05887.11 EAX66826.1 - 0.086 12.8 9.7 0.1 12.5 9.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nab1 PF04902.12 EAX66827.1 - 0.031 14.7 1.1 0.034 14.5 1.1 1.0 1 0 0 1 1 1 0 Conserved region in Nab1 Nucleopor_Nup85 PF07575.13 EAX66828.1 - 0.0078 14.8 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin FAS_N PF17828.1 EAX66830.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX66831.1 - 0.018 15.4 0.4 0.026 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX66831.1 - 0.38 9.7 2.2 0.41 9.6 2.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX66831.1 - 2.6 8.0 4.9 2.8 7.9 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MULE PF10551.9 EAX66832.1 - 6e-14 52.2 1.9 8.2e-14 51.8 0.3 1.9 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX66832.1 - 0.006 16.3 0.1 0.0081 15.9 0.1 1.2 1 0 0 1 1 1 1 Transposase Transposase_mut PF00872.18 EAX66832.1 - 0.012 14.5 0.3 0.015 14.1 0.3 1.1 1 0 0 1 1 1 0 Transposase, Mutator family TMP PF05017.14 EAX66833.1 - 0.026 15.0 3.0 11 7.2 0.2 3.0 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX66835.1 - 7.9e-09 34.9 1.4 1.2e-08 34.3 1.3 1.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX66835.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX66835.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_A32 PF04665.12 EAX66837.1 - 2.1e-07 30.6 2.1 3.2e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66837.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66837.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66837.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66837.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX66837.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX66837.1 - 0.55 10.4 8.3 5.8 7.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX66838.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX66838.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) TMP PF05017.14 EAX66840.1 - 0.21 12.3 6.0 12 7.1 0.2 3.2 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX66840.1 - 7.9 6.5 8.5 8.3 6.4 8.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 EAX66841.1 - 5.6e-227 753.9 15.6 6.4e-227 753.7 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX66841.1 - 0.0079 16.5 0.1 0.41 11.0 0.2 2.2 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX66841.1 - 0.043 13.6 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX66841.1 - 0.24 11.4 13.8 0.33 10.9 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4116 PF13475.6 EAX66842.1 - 0.016 14.9 0.3 0.08 12.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) UPF0253 PF06786.12 EAX66842.1 - 0.25 11.6 0.2 0.25 11.6 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) GPS2_interact PF15784.5 EAX66843.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX66844.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX66844.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NurA PF09376.10 EAX66845.1 - 0.0078 15.9 0.6 0.009 15.7 0.6 1.1 1 0 0 1 1 1 1 NurA domain MetOD2 PF18548.1 EAX66845.1 - 0.025 14.7 1.4 0.025 14.7 1.4 2.7 2 1 0 2 2 2 0 Metanogen output domain 2 Citrate_bind PF16114.5 EAX66845.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding CENP-O PF09496.10 EAX66845.1 - 4.2 7.3 8.5 4 7.4 2.7 2.2 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component DUF4106 PF13388.6 EAX66846.1 - 6.2e-196 651.6 14.0 7.6e-196 651.3 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) TFIIA PF03153.13 EAX66846.1 - 0.036 14.1 7.0 0.039 14.0 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3447 PF11929.8 EAX66848.1 - 2.7e-29 101.0 1.1 2.7e-29 101.0 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX66848.1 - 0.00028 21.4 0.0 0.0055 17.3 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pox_A32 PF04665.12 EAX66849.1 - 1.2e-05 24.9 2.6 1.6e-05 24.5 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66849.1 - 0.0041 16.8 0.2 0.0054 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX66849.1 - 0.0071 15.2 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX66849.1 - 0.029 13.9 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66849.1 - 0.04 13.7 0.2 0.25 11.1 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX66849.1 - 0.045 13.5 0.1 0.058 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX66849.1 - 0.097 12.6 1.2 1 9.3 0.0 3.1 3 1 0 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX66849.1 - 0.13 12.7 2.3 0.17 12.3 1.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_pol_B_2 PF03175.13 EAX66850.1 - 2.6e-21 76.0 3.8 3.2e-21 75.7 3.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66850.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX66852.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66852.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX66852.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66852.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) VirE PF05272.11 EAX66854.1 - 0.00052 19.8 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX66854.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX66854.1 - 0.14 11.1 0.2 12 4.7 0.1 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PTR PF12789.7 EAX66855.1 - 0.0077 16.3 0.4 0.0077 16.3 0.4 3.1 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX66855.1 - 0.036 12.9 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX66855.1 - 0.11 12.1 1.9 0.28 10.7 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX66855.1 - 1.4 9.5 5.6 22 5.7 0.1 3.3 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX66855.1 - 2.4 8.6 16.2 3.4 8.1 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX66856.1 - 4.2e-07 29.7 0.1 1.1e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein PSP PF04046.16 EAX66858.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX66859.1 - 5.1e-05 22.9 4.3 9.1e-05 22.0 4.3 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX66859.1 - 0.0015 18.5 1.8 0.003 17.6 0.3 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX66859.1 - 0.0048 16.5 0.4 0.0098 15.5 0.4 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX66859.1 - 0.04 14.2 1.5 0.12 12.7 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX66859.1 - 0.046 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Amidase02_C PF12123.8 EAX66860.1 - 0.0036 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX66861.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX66862.1 - 3.3e-32 112.2 32.7 6.5e-32 111.3 32.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) PT PF04886.12 EAX66862.1 - 1.4 8.5 44.1 0.05 13.2 37.9 1.8 2 0 0 2 2 2 0 PT repeat DUF2076 PF09849.9 EAX66862.1 - 6.6 6.7 17.0 6.8 6.7 17.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAS_N PF17828.1 EAX66863.1 - 0.009 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX66864.1 - 5e-10 38.8 1.5 9.8e-10 37.9 1.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Trypan_PARP PF05887.11 EAX66865.1 - 0.021 14.8 5.9 0.033 14.2 5.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX66866.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX66866.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX66868.1 - 4.6e-146 484.7 14.2 5.7e-146 484.4 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX66868.1 - 0.11 12.8 0.5 2.4 8.5 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX66868.1 - 0.6 10.6 7.3 2.1 8.9 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX66869.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP La PF05383.17 EAX66871.1 - 0.068 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 La domain RRM_9 PF18444.1 EAX66872.1 - 0.14 12.1 0.3 5.7 6.9 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif Fungal_trans PF04082.18 EAX66872.1 - 0.67 8.9 5.2 14 4.6 5.2 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF656 PF04920.12 EAX66872.1 - 1.8 8.5 3.7 7.8 6.4 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF656) KilA-N PF04383.13 EAX66873.1 - 6e-09 35.7 0.8 1.2e-08 34.8 0.1 1.8 1 1 1 2 2 2 1 KilA-N domain His_Phos_2 PF00328.22 EAX66873.1 - 0.028 13.8 2.4 0.033 13.6 2.4 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) KilA-N PF04383.13 EAX66875.1 - 5e-18 65.0 0.2 6e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX66875.1 - 0.083 12.9 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF2486 PF10667.9 EAX66876.1 - 4.8 7.3 35.8 0.92 9.7 11.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2486) DUF3839 PF12943.7 EAX66880.1 - 2.4e-122 407.0 7.3 2.7e-122 406.8 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX66880.1 - 0.14 12.5 1.0 0.37 11.1 0.9 1.8 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Gly-zipper_Omp PF13488.6 EAX66881.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX66881.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX66881.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2939 PF11159.8 EAX66882.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66882.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX66883.1 - 0.02 14.9 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX66884.1 - 5e-46 156.2 3.5 5.6e-46 156.0 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX66884.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein AAA_22 PF13401.6 EAX66887.1 - 6.2e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX66887.1 - 9.9e-05 22.4 3.7 0.00019 21.5 3.7 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66887.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66887.1 - 0.00077 19.3 0.8 0.0024 17.7 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66887.1 - 0.0039 16.9 0.5 0.45 10.2 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX66887.1 - 0.0077 16.6 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX66887.1 - 0.05 13.0 0.1 0.069 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX66887.1 - 0.083 13.3 0.1 0.38 11.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX66887.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TMP PF05017.14 EAX66889.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat YmaF PF12788.7 EAX66890.1 - 0.096 13.2 1.8 1.4 9.5 1.8 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX66890.1 - 0.45 10.8 7.6 1.2 9.4 0.3 3.1 3 0 0 3 3 3 0 Phage tail fibre repeat Spc7 PF08317.11 EAX66891.1 - 1.8 7.4 13.8 0.2 10.5 5.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EAX66891.1 - 4.9 6.9 9.6 1.5 8.6 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TetR_C_23 PF17931.1 EAX66891.1 - 9.3 6.4 6.9 27 4.9 1.9 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PapD_N PF00345.20 EAX66892.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX66892.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX66893.1 - 4.1e-135 448.8 8.7 4.8e-135 448.6 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX66893.1 - 0.017 15.3 0.1 0.058 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAX66893.1 - 0.35 11.5 2.3 0.69 10.6 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Pox_D5 PF03288.16 EAX66894.1 - 7.4e-05 23.2 2.8 0.00039 20.9 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX66894.1 - 0.025 13.7 0.9 0.034 13.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX66894.1 - 0.095 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain TMP PF05017.14 EAX66896.1 - 0.13 13.0 7.8 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX66896.1 - 4.3 7.3 8.2 4.7 7.2 8.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FYVE_2 PF02318.16 EAX66897.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PSP PF04046.16 EAX66898.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX66899.1 - 1.2e-06 28.2 2.1 1.2e-06 28.2 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66899.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66899.1 - 3.8e-05 23.5 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66899.1 - 0.00015 21.8 3.5 0.00032 20.7 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66899.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66899.1 - 0.0016 18.3 0.7 0.004 17.0 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66899.1 - 0.0018 17.9 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66899.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX66899.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX66899.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX66899.1 - 0.086 13.3 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX66899.1 - 0.22 11.8 4.5 4.3 7.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX66900.1 - 9.2e-05 22.9 3.3 0.00057 20.3 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX66900.1 - 0.045 14.4 0.2 0.093 13.4 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain KilA-N PF04383.13 EAX66901.1 - 2.9e-33 114.1 0.2 8.1e-33 112.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX66901.1 - 0.022 15.4 0.0 0.057 14.0 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family FAS_N PF17828.1 EAX66902.1 - 0.018 15.0 0.2 0.026 14.5 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX66903.1 - 0.035 14.5 0.1 0.035 14.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF2939 PF11159.8 EAX66904.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX66904.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX66904.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAX66905.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66905.1 - 0.035 14.1 0.4 0.047 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX66905.1 - 0.062 13.3 0.2 0.079 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4106 PF13388.6 EAX66906.1 - 1.8e-184 613.8 16.1 2.3e-184 613.5 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX66906.1 - 0.0087 16.3 0.1 0.46 10.8 0.1 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX66906.1 - 0.036 13.9 1.8 0.054 13.3 0.6 1.9 1 1 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) VP4_2 PF08935.10 EAX66906.1 - 0.1 13.2 0.7 0.23 12.1 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit PTR PF12789.7 EAX66907.1 - 1.1e-16 60.6 1.9 1.1e-16 60.6 1.9 5.2 3 2 2 5 5 4 1 Phage tail repeat like DUF3391 PF11871.8 EAX66907.1 - 0.0056 17.2 3.3 0.11 13.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX66907.1 - 0.021 14.5 0.1 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX66907.1 - 1.9 8.0 23.8 0.071 12.7 6.4 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX66908.1 - 5.7e-34 116.3 0.7 1.2e-33 115.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX66908.1 - 0.028 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Ank_4 PF13637.6 EAX66909.1 - 1.8e-29 101.7 8.4 2.6e-10 40.6 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66909.1 - 1.9e-28 98.9 2.9 1.9e-14 54.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX66909.1 - 4.5e-24 84.2 0.3 1.9e-07 31.2 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX66909.1 - 3.7e-23 79.1 1.0 5e-05 23.4 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EAX66909.1 - 1.7e-21 75.6 1.9 0.0011 19.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat HAUS-augmin3 PF14932.6 EAX66910.1 - 0.0075 15.9 1.7 0.011 15.4 1.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 YmgB PF10798.8 EAX66912.1 - 0.031 14.1 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DNA_alkylation PF08713.11 EAX66912.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme DNA_pol_B_2 PF03175.13 EAX66913.1 - 9.9e-16 57.6 3.0 1.3e-15 57.3 3.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66913.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX66914.1 - 1.7e-67 226.6 2.2 2.2e-67 226.2 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX66916.1 - 1.4e-31 108.3 9.6 1.4e-31 108.3 9.6 3.3 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX66916.1 - 0.045 13.5 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX66916.1 - 4.3 7.3 10.5 1.5 8.7 1.4 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF240) YmaF PF12788.7 EAX66917.1 - 0.17 12.4 1.6 2.3 8.8 1.7 2.0 1 1 0 1 1 1 0 YmaF family Pox_A32 PF04665.12 EAX66918.1 - 6.4e-07 29.1 2.8 6.4e-07 29.1 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX66918.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66918.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX66918.1 - 0.00015 21.8 3.1 0.00032 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66918.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66918.1 - 0.001 18.9 0.4 0.002 18.0 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX66918.1 - 0.0018 18.0 0.3 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX66918.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX66918.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX66918.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX66918.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX66918.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX66918.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) AbiJ_NTD4 PF18863.1 EAX66921.1 - 0.024 15.1 0.4 0.053 14.0 0.1 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX66921.1 - 0.032 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 VirK protein DNA_pol_B_2 PF03175.13 EAX66924.1 - 6.8e-20 71.4 9.9 8.7e-19 67.7 9.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX66924.1 - 0.095 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX66925.1 - 7.8e-74 247.2 4.5 9.3e-74 247.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX66925.1 - 0.093 11.1 1.4 0.13 10.7 1.4 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1493 PF07377.12 EAX66926.1 - 0.015 15.7 0.6 0.028 14.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX66928.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX66929.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein PapD_N PF00345.20 EAX66931.1 - 0.0094 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1031 PF06275.11 EAX66933.1 - 0.038 14.2 0.0 0.069 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX66933.1 - 0.069 13.2 0.3 0.33 11.1 0.2 2.0 1 1 1 2 2 2 0 Annexin KilA-N PF04383.13 EAX66934.1 - 1.6e-40 137.4 0.4 3.3e-40 136.4 0.4 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX66934.1 - 0.015 15.9 1.2 0.026 15.2 0.0 1.9 2 1 0 2 2 2 0 Parathyroid hormone family DUF4108 PF13390.6 EAX66935.1 - 3.4e-62 208.6 5.5 3.8e-62 208.4 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX66936.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain GPS2_interact PF15784.5 EAX66937.1 - 0.044 14.2 0.4 0.055 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX66938.1 - 0.33 10.9 7.1 0.34 10.9 7.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX66939.1 - 1.8e-08 34.3 1.2 1.8e-08 34.3 1.2 4.0 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX66939.1 - 0.19 11.3 12.9 0.38 10.3 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ribosomal_L30_N PF08079.12 EAX66939.1 - 0.23 11.7 3.6 0.16 12.2 0.6 2.2 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain DUF2939 PF11159.8 EAX66940.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66940.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX66942.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX66944.1 - 3.7e-65 219.8 4.1 4.8e-65 219.4 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX66944.1 - 0.53 10.4 3.0 3.2 7.9 1.3 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Amidase02_C PF12123.8 EAX66945.1 - 0.0041 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX66948.1 - 0.0024 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX66949.1 - 2.3e-25 88.4 7.9 2.3e-25 88.4 7.9 3.8 2 1 2 4 4 4 1 Phage tail repeat like HNH_3 PF13392.6 EAX66951.1 - 3.8e-07 29.8 0.4 7.8e-07 28.7 0.4 1.5 1 0 0 1 1 1 1 HNH endonuclease Pox_D5 PF03288.16 EAX66953.1 - 4.1e-05 24.0 2.3 0.00023 21.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX66953.1 - 0.039 13.0 1.1 0.053 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) PTR PF12789.7 EAX66954.1 - 1.6e-05 24.9 0.6 1.6e-05 24.9 0.6 2.8 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX66954.1 - 0.0047 16.3 0.6 0.0069 15.7 0.6 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 1 DUF445 PF04286.12 EAX66954.1 - 0.021 14.7 0.1 0.026 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX66954.1 - 0.088 13.3 0.1 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX66954.1 - 0.12 11.9 4.0 0.42 10.2 4.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4795 PF16043.5 EAX66957.1 - 0.0064 16.1 4.6 0.03 13.9 4.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF3447 PF11929.8 EAX66958.1 - 1.6e-38 130.5 5.6 1.6e-38 130.5 5.6 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX66958.1 - 3.8e-11 43.3 1.7 0.0006 20.3 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX66958.1 - 6.6e-11 42.6 2.8 3e-06 27.7 1.1 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX66958.1 - 8.2e-11 41.9 0.1 1.6e-06 28.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX66958.1 - 3.1e-08 33.2 1.9 0.0025 18.2 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EAX66958.1 - 3.5e-08 33.5 0.1 0.0002 21.6 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RL PF17797.1 EAX66958.1 - 0.7 9.9 4.0 3.1 7.8 0.2 3.1 3 0 0 3 3 3 0 RL domain DUF4107 PF13389.6 EAX66961.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX66962.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX66963.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX66964.1 - 0.043 14.3 1.0 0.064 13.7 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX66964.1 - 0.22 11.6 3.2 6 7.0 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_D5 PF03288.16 EAX66965.1 - 0.00084 19.8 2.7 0.0054 17.2 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX66965.1 - 0.051 12.6 1.0 0.069 12.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DNA_pol_B_2 PF03175.13 EAX66966.1 - 4.4e-17 62.1 2.4 5e-17 61.9 2.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX66967.1 - 4.3e-06 26.7 6.1 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX66967.1 - 0.3 11.6 4.1 3.4 8.3 2.1 2.8 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX66967.1 - 7.8 7.0 9.9 4.8 7.6 0.4 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat DUF257 PF03192.13 EAX66968.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX66968.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p KilA-N PF04383.13 EAX66969.1 - 5.6e-17 61.6 0.2 5.6e-17 61.6 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX66969.1 - 0.023 14.7 6.4 0.032 14.2 6.4 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FPN1 PF06963.12 EAX66969.1 - 0.18 10.4 0.2 0.21 10.1 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DNA_pol_B_2 PF03175.13 EAX66971.1 - 1.6e-20 73.4 3.7 2.9e-20 72.6 3.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX66971.1 - 0.064 12.6 0.1 0.093 12.0 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4106 PF13388.6 EAX66972.1 - 1.1e-20 74.3 3.7 1.1e-20 74.3 3.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX66974.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX66974.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX66974.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX66974.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX66974.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX66974.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX66975.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX66975.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX66975.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX66975.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX66975.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX66976.1 - 5.7e-39 134.0 5.3 8.3e-39 133.5 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX66976.1 - 0.079 13.1 0.1 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers GalP_UDP_transf PF01087.22 EAX66976.1 - 0.52 10.7 2.7 1.2 9.6 1.2 1.8 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain YmaF PF12788.7 EAX66977.1 - 0.19 12.3 1.5 11 6.6 0.1 2.1 1 1 0 2 2 2 0 YmaF family DUF4107 PF13389.6 EAX66978.1 - 3.1e-66 222.5 1.6 4.1e-66 222.1 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX66978.1 - 0.098 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF2362 PF10154.9 EAX66981.1 - 0.0016 17.5 3.8 0.0022 17.0 3.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Cupin_2 PF07883.11 EAX66981.1 - 0.23 11.2 0.1 61 3.4 0.0 2.9 3 0 0 3 3 3 0 Cupin domain LBP_C PF17386.2 EAX66981.1 - 0.44 10.5 5.7 41 4.2 0.0 3.7 4 0 0 4 4 4 0 Lacto-N-biose phosphorylase C-terminal domain AMPKBI PF04739.15 EAX66981.1 - 0.8 10.0 23.3 6.9 7.0 0.6 4.2 1 1 2 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain TMP PF05017.14 EAX66983.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX66984.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX66985.1 - 2.1e-96 323.8 4.7 2.1e-96 323.8 4.7 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX66985.1 - 0.64 8.6 5.1 0.81 8.2 5.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2939 PF11159.8 EAX66986.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX66986.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Phage_CP76 PF06892.11 EAX66987.1 - 0.63 9.6 14.1 17 4.9 0.8 4.0 1 1 3 4 4 4 0 Phage regulatory protein CII (CP76) KilA-N PF04383.13 EAX66988.1 - 4.5e-37 126.3 2.0 5.3e-37 126.1 0.1 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX66988.1 - 0.004 17.3 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX66988.1 - 0.16 10.5 0.2 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4107 PF13389.6 EAX66992.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX66993.1 - 2e-61 207.5 4.1 2.3e-61 207.3 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX66993.1 - 0.034 13.6 0.3 0.035 13.6 0.3 1.0 1 0 0 1 1 1 0 Z1 domain AAA_22 PF13401.6 EAX66996.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX66996.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX66996.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX66996.1 - 0.00089 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX66996.1 - 0.0026 17.5 0.2 0.27 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX66996.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX66996.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX66996.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX66996.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX66996.1 - 0.25 11.6 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Dehydrin PF00257.19 EAX66997.1 - 0.061 13.9 2.7 0.074 13.6 2.7 1.1 1 0 0 1 1 1 0 Dehydrin PapD_N PF00345.20 EAX66998.1 - 0.027 14.4 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX66998.1 - 0.039 14.0 0.4 0.057 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX66998.1 - 0.1 12.6 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3781 PF12636.7 EAX67000.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF1493 PF07377.12 EAX67001.1 - 0.044 14.2 0.5 0.098 13.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67001.1 - 0.6 10.2 3.3 13 5.9 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF1493 PF07377.12 EAX67002.1 - 0.019 15.4 0.5 0.038 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX67003.1 - 3.8e-07 29.8 4.4 5.4e-07 29.3 4.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67003.1 - 0.0015 18.2 0.2 0.0019 17.9 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67003.1 - 0.02 14.4 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX67003.1 - 0.072 12.8 0.3 0.11 12.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX67003.1 - 0.5 10.6 8.9 5.6 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF1493 PF07377.12 EAX67004.1 - 0.026 15.0 0.7 0.052 14.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX67005.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX67005.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF257 PF03192.13 EAX67006.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67006.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p KilA-N PF04383.13 EAX67007.1 - 8.4e-41 138.3 0.1 1.8e-40 137.2 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX67007.1 - 0.023 15.3 0.1 0.062 13.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family ABC1 PF03109.16 EAX67007.1 - 0.037 14.2 0.7 0.15 12.2 0.1 1.9 1 1 1 2 2 2 0 ABC1 family T5orf172 PF10544.9 EAX67008.1 - 1.2e-06 28.9 0.2 2.4e-06 28.0 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain DDR PF08841.10 EAX67009.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX67009.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain LIN37 PF15306.6 EAX67010.1 - 0.38 10.9 4.3 0.46 10.7 4.3 1.1 1 0 0 1 1 1 0 LIN37 PTR PF12789.7 EAX67011.1 - 4.6e-52 173.9 30.4 1.6e-34 117.7 14.7 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX67011.1 - 0.03 14.1 0.9 0.07 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX67012.1 - 2.5e-156 518.3 14.0 3.2e-156 517.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX67012.1 - 0.35 11.4 4.1 1.1 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX67012.1 - 1.1 9.6 3.5 0.96 9.8 1.1 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF4108 PF13390.6 EAX67013.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX67014.1 - 5.5e-05 23.5 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67014.1 - 6.5e-05 23.0 2.6 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67014.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67014.1 - 0.00077 19.3 0.8 0.0022 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67014.1 - 0.0027 17.5 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67014.1 - 0.0075 16.6 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67014.1 - 0.052 13.0 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67014.1 - 0.091 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67014.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67014.1 - 0.19 12.0 4.1 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX67014.1 - 0.77 10.2 4.2 0.38 11.2 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PapD_N PF00345.20 EAX67018.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX67019.1 - 8.4e-11 41.4 0.4 8.4e-11 41.4 0.4 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral TFCD_C PF12612.8 EAX67019.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DNA_pol_B_2 PF03175.13 EAX67020.1 - 3.2e-18 65.8 3.5 4e-18 65.5 3.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4107 PF13389.6 EAX67022.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67022.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Spo12 PF05032.12 EAX67023.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX67024.1 - 2.4e-22 79.5 4.4 3.2e-22 79.0 4.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67024.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Annexin PF00191.20 EAX67025.1 - 0.083 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Annexin DUF1031 PF06275.11 EAX67025.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) JMY PF15871.5 EAX67027.1 - 0.037 13.3 0.3 0.051 12.9 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX67027.1 - 0.13 12.3 0.3 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DUF3944 PF13099.6 EAX67028.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Knl1_RWD_C PF18210.1 EAX67028.1 - 0.22 12.0 8.5 5.4 7.6 6.3 2.5 1 1 1 2 2 2 0 Knl1 RWD C-terminal domain DUF4841 PF16129.5 EAX67029.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) PSP PF04046.16 EAX67031.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67032.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX67033.1 - 1.8e-20 73.3 4.9 2.3e-20 72.9 4.9 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67033.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Gly_rich PF12810.7 EAX67034.1 - 2.8e-29 102.8 39.0 3.4e-29 102.5 39.0 1.0 1 0 0 1 1 1 1 Glycine rich protein TMP PF05017.14 EAX67035.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX67038.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX67040.1 - 0.049 14.1 0.4 0.093 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ResIII PF04851.15 EAX67042.1 - 2.2e-05 24.6 0.9 3.5e-05 23.9 0.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67042.1 - 0.00028 20.7 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX67042.1 - 0.00041 20.6 0.0 0.00063 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX67042.1 - 0.0012 18.7 0.2 0.0019 18.1 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67042.1 - 0.0062 16.9 0.0 0.0079 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67042.1 - 0.036 13.5 0.1 0.048 13.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX67042.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX67042.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX67042.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX67042.1 - 0.62 10.5 3.4 0.38 11.2 0.6 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Chal_sti_synt_N PF00195.19 EAX67043.1 - 0.022 14.2 0.2 0.038 13.4 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX67043.1 - 3 7.7 7.5 7.4 6.4 7.5 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX67044.1 - 3.2e-92 308.4 9.3 3.7e-92 308.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX67044.1 - 0.032 13.7 0.4 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 Z1 domain DUF1493 PF07377.12 EAX67045.1 - 0.027 14.9 0.7 0.054 14.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Glyco_hydro_30 PF02055.16 EAX67046.1 - 5.6e-14 51.9 0.0 7.8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydr_30_2 PF14587.6 EAX67046.1 - 0.029 14.0 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 DUF2939 PF11159.8 EAX67048.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67048.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX67049.1 - 0.0051 16.8 0.2 0.0067 16.4 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Gly-zipper_Omp PF13488.6 EAX67050.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX67050.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX67050.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX67050.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX67050.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF1493 PF07377.12 EAX67051.1 - 0.062 13.8 0.5 0.14 12.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) UPF0242 PF06785.11 EAX67052.1 - 0.00025 21.2 10.4 0.00025 21.2 10.4 3.4 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 EAX67052.1 - 0.00065 20.0 4.4 0.00065 20.0 4.4 4.0 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EAX67052.1 - 0.0012 18.4 44.7 0.0029 17.1 24.9 3.0 1 1 1 2 2 2 2 Golgin subfamily A member 5 SlyX PF04102.12 EAX67052.1 - 0.0013 19.3 30.9 0.24 12.0 0.5 6.7 2 1 5 7 7 7 2 SlyX Fib_alpha PF08702.10 EAX67052.1 - 0.0014 18.8 11.8 0.0014 18.8 11.8 3.9 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family DUF745 PF05335.13 EAX67052.1 - 0.0044 16.8 25.9 0.014 15.1 14.3 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF745) HOOK PF05622.12 EAX67052.1 - 0.0071 14.6 37.3 0.1 10.7 37.3 2.1 1 1 0 1 1 1 1 HOOK protein TSC22 PF01166.18 EAX67052.1 - 0.018 15.4 1.9 0.018 15.4 1.9 5.7 4 2 2 6 6 6 0 TSC-22/dip/bun family NPV_P10 PF05531.12 EAX67052.1 - 0.02 15.3 12.9 0.56 10.7 0.1 4.7 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 EAX67052.1 - 0.041 14.1 44.2 0.051 13.8 6.3 4.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 EAX67052.1 - 0.19 12.1 41.8 0.32 11.4 1.0 6.6 5 1 2 7 7 6 0 Csm1 N-terminal domain HALZ PF02183.18 EAX67052.1 - 0.24 11.7 14.8 0.19 12.0 2.2 4.8 4 0 0 4 4 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 EAX67052.1 - 0.27 11.3 48.2 2 8.5 1.3 4.7 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EAX67052.1 - 0.31 11.2 45.7 0.12 12.5 4.3 4.1 1 1 2 3 3 3 0 Tropomyosin like ERM PF00769.19 EAX67052.1 - 0.47 10.2 40.3 1.2 8.9 13.5 2.4 1 1 0 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EAX67052.1 - 0.48 10.4 49.5 0.11 12.6 18.7 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA1 PF07160.12 EAX67052.1 - 0.55 10.0 29.3 0.29 10.9 14.2 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 PKcGMP_CC PF16808.5 EAX67052.1 - 0.63 10.0 12.7 0.65 9.9 0.2 5.1 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DHR10 PF18595.1 EAX67052.1 - 0.99 9.5 43.3 0.081 13.0 10.4 3.9 1 1 2 4 4 3 0 Designed helical repeat protein 10 domain MT PF12777.7 EAX67052.1 - 1.1 8.2 8.0 0.1 11.6 1.5 2.4 1 1 0 2 2 2 0 Microtubule-binding stalk of dynein motor SesA PF17107.5 EAX67052.1 - 1.2 9.3 16.9 0.027 14.6 6.3 3.0 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Fez1 PF06818.15 EAX67052.1 - 1.4 9.3 42.3 1.7e+02 2.5 2.4 3.2 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 EAX67052.1 - 1.4 9.5 49.4 4.3 7.9 15.9 3.6 2 2 1 3 3 3 0 Apg6 coiled-coil region DUF948 PF06103.11 EAX67052.1 - 1.8 8.9 11.5 3.9 7.8 0.2 4.3 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CCDC144C PF14915.6 EAX67052.1 - 1.9 7.6 46.0 0.35 9.9 5.3 3.0 1 1 1 3 3 3 0 CCDC144C protein coiled-coil region GAS PF13851.6 EAX67052.1 - 2 7.7 45.1 2.3 7.5 13.8 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EAX67052.1 - 2.1 7.1 46.1 1.1 8.0 14.2 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Lebercilin PF15619.6 EAX67052.1 - 2.8 7.6 46.5 7.3 6.2 24.2 4.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Uso1_p115_C PF04871.13 EAX67052.1 - 3.5 8.0 44.9 0.5 10.7 8.5 4.3 2 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.20 EAX67052.1 - 4.2 6.7 40.2 5.2 6.4 9.5 4.4 1 1 3 4 4 4 0 Tropomyosin Prefoldin_3 PF13758.6 EAX67052.1 - 4.7 7.3 20.6 2.3 8.3 6.1 3.9 2 2 2 4 4 4 0 Prefoldin subunit GrpE PF01025.19 EAX67052.1 - 4.9 6.8 38.7 2.6 7.7 2.2 4.6 1 1 3 4 4 4 0 GrpE Myosin_tail_1 PF01576.19 EAX67052.1 - 5.6 4.6 42.8 13 3.5 42.7 1.5 1 1 0 1 1 1 0 Myosin tail DUF724 PF05266.14 EAX67052.1 - 6.1 6.6 38.3 1.4 8.7 7.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 EAX67052.1 - 6.9 7.2 33.7 2.5 8.6 3.2 6.2 3 1 4 7 7 7 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 EAX67052.1 - 7.4 3.9 36.2 1.6 6.2 8.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ADIP PF11559.8 EAX67052.1 - 7.7 6.6 47.7 9.3 6.3 6.7 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 EAX67052.1 - 8.2 5.2 40.8 0.62 8.9 22.6 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like YscO PF07321.12 EAX67052.1 - 8.8 6.3 34.5 2.4 8.1 2.0 3.6 1 1 2 4 4 4 0 Type III secretion protein YscO Pox_A32 PF04665.12 EAX67053.1 - 7.2e-05 22.4 2.4 7.2e-05 22.4 2.4 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67053.1 - 0.04 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX67053.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Amidase02_C PF12123.8 EAX67054.1 - 0.0044 16.7 0.1 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX67055.1 - 7.7e-64 213.9 6.1 8.6e-64 213.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX67057.1 - 5.2e-07 29.5 0.4 1.3e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX67058.1 - 1.3e-54 185.2 4.2 1.5e-54 185.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX67058.1 - 0.034 13.6 0.1 0.038 13.5 0.1 1.0 1 0 0 1 1 1 0 Z1 domain DNA_pol_B_2 PF03175.13 EAX67059.1 - 3e-10 39.6 2.9 1.4e-09 37.4 2.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX67059.1 - 0.099 12.6 0.0 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX67059.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Amidase02_C PF12123.8 EAX67060.1 - 0.0034 17.0 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF5439 PF17507.2 EAX67061.1 - 1.4e-07 31.6 0.0 1.3e+02 2.8 0.0 8.0 9 0 0 9 9 9 0 Family of unknown function (DUF5439) Glyco_hydro_68 PF02435.16 EAX67061.1 - 1.6e-06 27.3 0.0 22 3.8 0.0 6.1 1 1 7 8 8 8 5 Levansucrase/Invertase IKKbetaNEMObind PF12179.8 EAX67061.1 - 9e-05 22.4 0.0 4.4e+02 1.0 0.0 7.2 8 0 0 8 8 8 0 I-kappa-kinase-beta NEMO binding domain EP400_N PF15790.5 EAX67061.1 - 0.00021 20.3 0.0 63 2.2 0.0 5.7 1 1 7 8 8 8 0 E1A-binding protein p400, N-terminal zf-C2H2_3rep PF18868.1 EAX67061.1 - 0.0061 17.2 0.0 62 4.3 0.0 5.0 7 2 0 9 9 9 0 Zinc finger C2H2-type, 3 repeats Tht1 PF04163.12 EAX67061.1 - 1.2 7.8 6.9 13 4.4 0.2 3.6 1 1 3 4 4 4 0 Tht1-like nuclear fusion protein Amidase02_C PF12123.8 EAX67062.1 - 0.0021 17.7 0.0 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX67062.1 - 0.17 11.7 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Filament PF00038.21 EAX67063.1 - 0.0006 19.5 25.4 0.015 14.9 11.3 2.3 1 1 1 2 2 2 2 Intermediate filament protein APG6_N PF17675.1 EAX67063.1 - 0.0027 18.2 30.2 0.088 13.3 0.9 3.5 1 1 2 3 3 3 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EAX67063.1 - 0.0033 17.5 5.0 0.0033 17.5 5.0 3.9 2 1 0 4 4 4 2 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 EAX67063.1 - 0.0054 16.3 15.9 0.0054 16.3 15.9 2.7 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Cep57_CLD_2 PF14197.6 EAX67063.1 - 0.011 15.9 23.4 6.5 6.9 2.3 4.9 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 IFP_35_N PF07334.13 EAX67063.1 - 0.038 14.1 2.3 0.038 14.1 2.3 4.0 2 1 2 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MAD PF05557.13 EAX67063.1 - 0.039 12.3 33.1 0.089 11.1 33.1 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein ERM PF00769.19 EAX67063.1 - 0.043 13.6 24.3 0.063 13.1 24.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EAX67063.1 - 0.061 13.3 31.1 0.52 10.3 9.2 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cytochrom_C_2 PF01322.20 EAX67063.1 - 0.11 13.4 2.7 0.21 12.5 0.4 2.5 1 1 1 2 2 2 0 Cytochrome C' Myosin_tail_1 PF01576.19 EAX67063.1 - 0.11 10.3 29.6 0.0085 14.0 12.0 2.8 2 1 1 3 3 3 0 Myosin tail Fez1 PF06818.15 EAX67063.1 - 0.18 12.2 31.5 0.044 14.2 20.8 2.4 1 1 1 2 2 2 0 Fez1 HsbA PF12296.8 EAX67063.1 - 0.18 12.2 7.2 0.92 10.0 0.5 3.3 3 1 0 3 3 3 0 Hydrophobic surface binding protein A KASH_CCD PF14662.6 EAX67063.1 - 0.3 10.9 35.0 2 8.2 27.8 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EAX67063.1 - 0.31 11.2 26.4 0.074 13.3 17.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EAX67063.1 - 0.33 11.0 32.7 2.5 8.1 15.2 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 EAX67063.1 - 0.33 10.6 32.8 0.15 11.7 7.3 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 EAX67063.1 - 0.33 10.6 31.1 0.073 12.8 3.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4279 PF14106.6 EAX67063.1 - 0.54 10.5 5.8 0.27 11.5 1.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) Golgin_A5 PF09787.9 EAX67063.1 - 0.97 8.8 31.9 2.4 7.5 19.0 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 CLZ PF16526.5 EAX67063.1 - 1.8 9.0 18.2 0.38 11.1 3.5 3.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EAX67063.1 - 2.2 7.1 32.5 23 3.7 28.8 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EAX67063.1 - 2.8 8.1 31.0 0.21 11.8 11.1 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 EAX67063.1 - 2.9 7.4 32.0 0.85 9.2 28.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF489 PF04356.12 EAX67063.1 - 3.2 7.7 11.9 6.4 6.7 7.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF4342 PF14242.6 EAX67063.1 - 3.2 7.8 6.6 14 5.8 0.2 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4342) DUF1664 PF07889.12 EAX67063.1 - 4.4 7.4 20.4 4.2 7.4 2.8 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 EAX67063.1 - 5.2 7.3 20.0 0.61 10.3 0.9 4.4 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II YtxH PF12732.7 EAX67063.1 - 6.7 7.3 9.0 9.8 6.8 2.8 3.8 2 1 1 3 3 3 0 YtxH-like protein Lectin_N PF03954.14 EAX67063.1 - 7.1 6.4 22.1 0.16 11.7 5.0 3.3 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Prefoldin_2 PF01920.20 EAX67063.1 - 8.1 6.5 28.4 0.9 9.5 0.7 4.9 3 1 1 4 4 4 0 Prefoldin subunit HalX PF08663.10 EAX67063.1 - 9.5 6.6 10.4 5 7.5 0.1 3.9 3 1 2 5 5 4 0 HalX domain BRO1 PF03097.18 EAX67064.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF1493 PF07377.12 EAX67065.1 - 0.034 14.6 0.7 0.069 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Membralin PF09746.9 EAX67066.1 - 1.9 7.5 3.6 2 7.3 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF2400 PF09674.10 EAX67067.1 - 0.027 14.5 0.5 0.036 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX67067.1 - 0.043 13.8 0.4 0.051 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) IstB_IS21 PF01695.17 EAX67069.1 - 2.3e-05 24.2 0.4 0.25 11.0 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67069.1 - 2.4e-05 24.6 0.1 0.00018 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67069.1 - 0.00011 22.2 3.2 0.00024 21.2 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX67069.1 - 0.00038 20.0 4.3 0.0004 19.9 2.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX67069.1 - 0.00046 20.0 0.1 0.00085 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67069.1 - 0.001 18.9 0.6 0.0029 17.4 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67069.1 - 0.0012 18.5 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67069.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67069.1 - 0.051 13.2 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67069.1 - 0.062 13.7 0.1 0.53 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX67069.1 - 0.062 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX67069.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67069.1 - 0.33 11.2 4.3 8.5 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX67070.1 - 2.9e-52 176.4 4.3 3.2e-52 176.3 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX67071.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX67073.1 - 1.3e-45 154.9 2.9 1.4e-45 154.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX67073.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF1493 PF07377.12 EAX67075.1 - 0.051 14.0 0.4 0.12 12.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX67076.1 - 2.5e-05 23.8 0.4 2.5e-05 23.8 0.4 1.5 2 0 0 2 2 2 1 Poxvirus A32 protein Glyco_trans_1_3 PF13528.6 EAX67076.1 - 0.033 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 tRNA_synt_1c_R1 PF04558.15 EAX67076.1 - 0.064 13.3 0.6 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 PSP PF04046.16 EAX67078.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX67079.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat YmaF PF12788.7 EAX67082.1 - 0.15 12.6 1.5 6.4 7.4 0.1 2.0 1 1 0 1 1 1 0 YmaF family Pox_A32 PF04665.12 EAX67083.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67083.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67083.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67083.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67083.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67083.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67083.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67083.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67083.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67083.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67083.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67083.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PSP PF04046.16 EAX67084.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67085.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat AbiJ_NTD4 PF18863.1 EAX67086.1 - 0.017 15.6 0.1 0.024 15.1 0.1 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Pex14_N PF04695.13 EAX67087.1 - 1.2 9.8 11.9 1.4 9.6 11.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_A32 PF04665.12 EAX67088.1 - 9.9e-05 21.9 3.6 9.9e-05 21.9 3.6 1.5 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67088.1 - 0.0031 17.5 0.9 0.0064 16.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX67088.1 - 0.0074 15.9 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX67088.1 - 0.057 13.7 1.9 0.14 12.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) KilA-N PF04383.13 EAX67092.1 - 3.1e-16 59.2 0.3 1e-15 57.5 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX67093.1 - 0.006 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX67094.1 - 1.3e-76 255.3 12.6 1.5e-76 255.1 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PRA-PH PF01503.17 EAX67095.1 - 0.053 14.0 2.6 0.059 13.8 2.6 1.0 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4199 PF13858.6 EAX67095.1 - 0.25 11.7 0.4 0.25 11.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3839 PF12943.7 EAX67096.1 - 3.8e-118 393.3 12.1 4.8e-118 392.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67096.1 - 0.041 14.3 2.2 5.3 7.6 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX67096.1 - 0.11 12.4 2.7 0.18 11.6 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase LD_cluster2 PF18163.1 EAX67096.1 - 0.23 10.9 0.8 0.93 9.0 0.1 2.3 2 1 0 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX67097.1 - 2.4e-93 312.1 7.9 2.8e-93 311.9 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX67098.1 - 5.7e-63 208.9 39.0 2.2e-34 117.3 14.5 5.2 2 2 4 6 6 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX67098.1 - 0.085 12.6 0.6 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX67098.1 - 0.09 12.5 3.5 0.92 9.3 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) DUF4404 PF14357.6 EAX67098.1 - 6.7 7.4 7.1 16 6.2 0.2 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) DUF3839 PF12943.7 EAX67099.1 - 1.2e-79 267.3 10.5 1.5e-79 266.9 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX67100.1 - 5.4e-52 173.7 38.8 9.2e-33 112.1 16.7 3.0 3 1 1 4 4 4 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX67100.1 - 0.77 10.1 5.6 57 4.1 0.1 4.5 2 1 3 5 5 5 0 TFIIH p62 subunit, N-terminal domain Pox_A32 PF04665.12 EAX67101.1 - 2.9e-07 30.2 0.2 6e-07 29.2 0.1 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF2939 PF11159.8 EAX67102.1 - 0.018 15.4 0.5 0.026 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX67102.1 - 1.2 8.1 2.7 1.3 8.0 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX67102.1 - 2 8.4 5.9 2.2 8.3 5.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX67103.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4106 PF13388.6 EAX67104.1 - 9.9e-88 295.2 4.0 9.9e-88 295.2 4.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF885 PF05960.11 EAX67104.1 - 0.00083 19.1 2.7 0.0011 18.8 2.7 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) SATase_N PF06426.14 EAX67105.1 - 0.06 13.7 25.1 54 4.2 0.6 8.1 1 1 9 10 10 10 0 Serine acetyltransferase, N-terminal DUF5301 PF17225.3 EAX67105.1 - 0.12 12.8 49.6 6.1 7.3 6.6 6.3 1 1 6 7 7 7 0 Domain of unknown function (DUF5300) Atg31 PF09795.9 EAX67105.1 - 1.2 9.1 106.3 19 5.2 7.0 10.5 1 1 12 13 13 13 0 Autophagy-related protein 31 Peptidase_S24 PF00717.23 EAX67105.1 - 3 7.9 50.4 18 5.4 0.7 10.1 1 1 10 11 11 11 0 Peptidase S24-like DUF1287 PF06940.11 EAX67105.1 - 3.2 7.4 18.8 46 3.6 0.6 5.5 1 1 6 7 7 7 0 Domain of unknown function (DUF1287) PSP PF04046.16 EAX67106.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67107.1 - 0.23 12.2 4.3 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX67110.1 - 3.1e-59 199.0 8.9 3.5e-59 198.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX67110.1 - 0.04 14.2 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX67111.1 - 8.3e-05 23.0 2.4 0.0005 20.5 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PadR PF03551.14 EAX67112.1 - 0.08 12.9 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX67113.1 - 4.8e-09 35.6 1.0 8.1e-09 34.9 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX67113.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX67113.1 - 0.089 12.8 0.0 0.66 10.0 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX67113.1 - 0.23 10.1 2.8 2.6 6.6 2.8 2.3 1 1 0 1 1 1 0 DNA polymerase family B Pox_A32 PF04665.12 EAX67114.1 - 6.7e-07 29.0 2.3 6.7e-07 29.0 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67114.1 - 3.1e-05 24.3 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67114.1 - 4.7e-05 23.2 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67114.1 - 0.00015 21.9 3.2 0.00034 20.7 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67114.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67114.1 - 0.0012 18.6 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67114.1 - 0.0017 18.0 0.4 0.01 15.5 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67114.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67114.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67114.1 - 0.084 13.3 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67114.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67114.1 - 0.38 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MG2 PF01835.19 EAX67115.1 - 1.3e-05 25.5 0.1 0.002 18.5 0.1 3.0 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX67115.1 - 8.7e-05 22.8 1.3 0.0087 16.3 0.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) Cohesin PF00963.18 EAX67115.1 - 0.00034 20.9 6.9 0.00094 19.4 2.3 2.3 1 1 1 2 2 2 1 Cohesin domain ChitinaseA_N PF08329.10 EAX67115.1 - 0.0035 17.0 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Chitinase A, N-terminal domain Y_Y_Y PF07495.13 EAX67115.1 - 0.0086 16.0 1.2 4.8 7.2 0.1 2.7 2 0 0 2 2 2 2 Y_Y_Y domain DUF2914 PF11141.8 EAX67115.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Lipocalin PF00061.23 EAX67115.1 - 0.021 15.0 1.7 0.042 14.0 1.7 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PKD PF00801.20 EAX67115.1 - 0.032 14.1 0.2 0.29 11.0 0.1 2.6 2 1 0 2 2 2 0 PKD domain DUF4469 PF14734.6 EAX67115.1 - 0.036 14.2 1.6 0.33 11.1 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold NPCBM_assoc PF10633.9 EAX67115.1 - 0.036 14.3 0.2 0.036 14.3 0.2 3.0 5 1 0 5 5 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Invasin_D3 PF09134.10 EAX67115.1 - 0.065 13.5 2.0 0.12 12.7 1.5 1.7 1 1 0 1 1 1 0 Invasin, domain 3 Sipho_Gp157 PF05565.11 EAX67115.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 He_PIG PF05345.12 EAX67115.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.6 4 0 0 4 4 4 0 Putative Ig domain IstB_IS21 PF01695.17 EAX67116.1 - 2.4e-05 24.1 0.3 0.29 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67116.1 - 2.8e-05 24.4 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX67116.1 - 3.4e-05 23.4 2.1 3.4e-05 23.4 2.1 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX67116.1 - 0.00031 20.8 4.4 0.00048 20.2 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67116.1 - 0.00053 19.8 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67116.1 - 0.0016 18.3 1.1 0.0032 17.3 0.4 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67116.1 - 0.0027 17.4 2.6 0.0096 15.6 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67116.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX67116.1 - 0.061 13.4 0.7 0.99 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Elong_Iki1 PF10483.9 EAX67116.1 - 0.062 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX67116.1 - 0.066 12.8 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67116.1 - 0.073 13.5 0.1 0.7 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67116.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67116.1 - 0.47 10.7 4.7 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX67116.1 - 4.9 7.9 11.1 0.28 11.9 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 AbiJ_NTD4 PF18863.1 EAX67117.1 - 0.051 14.0 0.4 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 KilA-N PF04383.13 EAX67118.1 - 2.1e-41 140.3 0.6 4.4e-41 139.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX67118.1 - 0.0088 15.3 0.2 0.03 13.6 0.1 1.7 1 1 1 2 2 2 1 Acyl transferase DUF3213 PF11491.8 EAX67118.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX67118.1 - 0.1 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Podoplanin PF05808.11 EAX67119.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 EAX67119.1 - 0.98 10.3 3.1 7.4 7.5 0.4 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMP PF05017.14 EAX67121.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX67123.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX67123.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX67123.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX67123.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX67124.1 - 3.1e-133 442.7 10.0 3.5e-133 442.5 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67124.1 - 0.089 13.3 2.0 1.2 9.7 0.7 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HD_3 PF13023.6 EAX67125.1 - 0.056 13.4 0.7 0.075 13.0 0.7 1.1 1 0 0 1 1 1 0 HD domain Paf1 PF03985.13 EAX67125.1 - 0.87 8.5 8.4 1 8.3 8.4 1.0 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EAX67125.1 - 1.3 7.7 3.0 1.4 7.6 3.0 1.1 1 0 0 1 1 1 0 Presenilin FAS_N PF17828.1 EAX67127.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Nab1 PF04902.12 EAX67128.1 - 0.031 14.7 1.1 0.034 14.5 1.1 1.0 1 0 0 1 1 1 0 Conserved region in Nab1 Pox_A32 PF04665.12 EAX67129.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67129.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67129.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67129.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX67130.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) SL4P PF17618.2 EAX67131.1 - 0.078 13.0 1.6 10 6.3 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Phage_fiber PF03335.13 EAX67133.1 - 0.036 14.2 12.8 2.5 8.5 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX67133.1 - 0.11 12.5 9.2 0.26 11.4 2.3 3.0 3 1 0 3 3 3 0 Phage tail repeat like YmaF PF12788.7 EAX67133.1 - 0.42 11.2 5.4 11 6.6 0.2 3.0 2 1 0 2 2 2 0 YmaF family TMP PF05017.14 EAX67136.1 - 0.085 13.5 6.1 11 7.2 0.3 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX67138.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67139.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX67140.1 - 1.1e-08 34.5 2.3 1.4e-08 34.0 1.4 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX67140.1 - 0.073 12.6 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX67140.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4378 PF14309.6 EAX67142.1 - 0.073 13.4 0.1 0.39 11.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) KilA-N PF04383.13 EAX67143.1 - 5.8e-09 35.8 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX67144.1 - 3.1e-61 206.9 3.0 3.5e-61 206.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX67144.1 - 0.014 14.9 0.2 0.015 14.8 0.2 1.0 1 0 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX67144.1 - 0.087 13.3 1.2 0.23 11.9 1.2 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mucin-like PF16058.5 EAX67145.1 - 6.2e-39 132.1 11.7 1.4e-13 50.8 0.1 3.7 1 1 1 3 3 3 3 Mucin-like BOF PF04076.13 EAX67145.1 - 0.011 15.8 44.9 3.4 7.8 5.4 5.6 1 1 5 6 6 6 0 Bacterial OB fold (BOF) protein DUF4275 PF14101.6 EAX67145.1 - 0.014 15.5 32.8 13 5.9 1.6 7.3 1 1 8 9 9 9 0 Domain of unknown function (DUF4275) DUF2501 PF10696.9 EAX67145.1 - 0.28 11.5 39.5 16 5.8 0.7 7.2 1 1 11 12 12 12 0 Protein of unknown function (DUF2501) RNaseH_like PF04308.12 EAX67145.1 - 3.9 7.4 29.3 44 4.0 1.8 6.9 1 1 6 7 7 7 0 Ribonuclease H-like Baculo_gp41 PF04700.12 EAX67145.1 - 4.6 7.0 35.4 21 4.9 6.5 4.0 1 1 2 4 4 4 0 Structural glycoprotein p40/gp41 conserved region NPA PF16469.5 EAX67146.1 - 0.052 14.1 0.4 8.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 IstB_IS21 PF01695.17 EAX67147.1 - 2.1e-05 24.3 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67147.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX67147.1 - 5.9e-05 22.7 1.9 5.9e-05 22.7 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX67147.1 - 0.00051 20.1 5.3 0.00091 19.3 4.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67147.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67147.1 - 0.0027 17.5 1.6 0.0071 16.2 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67147.1 - 0.0043 16.7 2.7 0.014 15.1 0.2 2.5 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67147.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX67147.1 - 0.053 13.6 0.7 0.85 9.7 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX67147.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67147.1 - 0.073 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67147.1 - 0.088 12.3 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67147.1 - 1.1 9.5 5.9 9.9 6.5 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX67147.1 - 3.4 8.4 10.8 0.29 11.8 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 MULE PF10551.9 EAX67148.1 - 2.7e-05 24.5 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX67148.1 - 0.046 14.4 0.1 0.094 13.4 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain MKLP1_Arf_bdg PF16540.5 EAX67150.1 - 2.5 8.2 7.3 3.1 7.9 7.3 1.2 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Glutaminase PF04960.15 EAX67150.1 - 3.2 6.8 8.0 2.3 7.3 1.1 2.0 1 1 1 2 2 2 0 Glutaminase KilA-N PF04383.13 EAX67151.1 - 1.4e-06 28.1 1.0 1.9e-06 27.7 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF2939 PF11159.8 EAX67152.1 - 0.025 15.0 0.2 0.035 14.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX67153.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX67154.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67154.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67154.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67154.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX67155.1 - 1.8e-07 31.7 0.7 2e-06 28.3 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain DUF4108 PF13390.6 EAX67157.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX67160.1 - 3.1e-41 139.7 1.0 6.2e-41 138.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX67160.1 - 0.37 10.8 2.8 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein DUF4107 PF13389.6 EAX67161.1 - 2.3e-73 245.7 4.4 2.8e-73 245.4 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX67161.1 - 0.17 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1493 PF07377.12 EAX67162.1 - 0.053 14.0 0.5 0.11 13.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX67164.1 - 6.8e-40 137.0 3.8 9.4e-40 136.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) IstB_IS21 PF01695.17 EAX67165.1 - 1.2e-05 25.2 1.2 0.27 10.9 0.0 3.2 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67165.1 - 6.3e-05 23.0 4.6 0.00016 21.7 4.5 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX67165.1 - 0.00013 22.3 0.2 0.00062 20.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX67165.1 - 0.00029 20.7 0.1 0.00061 19.6 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 EAX67165.1 - 0.0012 18.4 0.1 0.05 13.0 0.1 2.3 1 1 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.6 EAX67165.1 - 0.0017 18.2 0.6 0.0031 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67165.1 - 0.0017 18.7 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX67165.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX67165.1 - 0.11 12.9 0.1 0.46 10.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAX67165.1 - 0.24 11.1 0.0 0.49 10.1 0.0 1.6 2 1 0 2 2 2 0 AAA domain DNA_pol_B_2 PF03175.13 EAX67166.1 - 5.8e-09 35.3 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX67166.1 - 0.086 12.4 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX67166.1 - 0.11 12.4 0.0 0.8 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX67166.1 - 0.22 10.2 2.0 2.6 6.6 1.9 2.3 1 1 0 1 1 1 0 DNA polymerase family B KilA-N PF04383.13 EAX67167.1 - 4e-35 120.0 0.3 7.7e-35 119.1 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain Cep57_MT_bd PF06657.13 EAX67167.1 - 0.18 12.2 5.7 10 6.7 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FPN1 PF06963.12 EAX67167.1 - 0.23 10.0 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4795 PF16043.5 EAX67168.1 - 0.0091 15.6 6.0 0.073 12.7 6.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PapD_N PF00345.20 EAX67170.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX67170.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX67170.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PTR PF12789.7 EAX67171.1 - 4.4e-54 180.4 36.7 4.7e-35 119.4 16.2 4.2 3 2 2 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX67171.1 - 0.034 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Spo12 PF05032.12 EAX67173.1 - 0.55 10.2 8.3 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX67174.1 - 2.9e-21 75.9 4.6 3.4e-21 75.6 4.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX67175.1 - 2.3e-21 76.2 4.2 2.9e-21 75.9 4.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RFX_DNA_binding PF02257.15 EAX67176.1 - 9.8e-05 22.9 0.2 0.00015 22.3 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX67176.1 - 0.00025 21.5 2.3 0.00038 20.9 2.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX67176.1 - 0.039 13.9 0.6 0.078 13.0 0.1 1.7 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX67179.1 - 0.00012 21.6 0.3 0.00014 21.4 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX67179.1 - 0.0039 17.5 0.9 0.0039 17.5 0.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX67181.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67181.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67181.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67181.1 - 0.00011 22.2 2.7 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67181.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67181.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67181.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67181.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX67181.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX67181.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67181.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67181.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67181.1 - 0.3 11.4 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX67182.1 - 1.8e-06 28.4 0.2 3.7e-06 27.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX67183.1 - 1.2e-11 44.1 0.8 2.6e-11 43.1 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67183.1 - 0.0082 15.5 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein Gly_rich PF12810.7 EAX67184.1 - 4.5e-32 111.9 20.6 6.9e-32 111.3 20.6 1.3 1 1 0 1 1 1 1 Glycine rich protein DUF4107 PF13389.6 EAX67186.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX67186.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase TMP PF05017.14 EAX67187.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat BRO1 PF03097.18 EAX67188.1 - 0.033 13.0 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX67188.1 - 0.24 11.9 1.7 16 6.1 0.1 2.3 1 1 0 2 2 2 0 YmaF family DUF1493 PF07377.12 EAX67189.1 - 0.025 15.1 0.5 0.049 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Mito_fiss_reg PF05308.11 EAX67191.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX67191.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GPS2_interact PF15784.5 EAX67192.1 - 0.047 14.1 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Collagen_bind_2 PF12904.7 EAX67193.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF1731 PF08338.11 EAX67194.1 - 0.14 12.0 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_D5 PF03288.16 EAX67195.1 - 0.00029 21.3 3.3 0.0022 18.5 3.3 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX67195.1 - 0.038 13.1 1.1 0.054 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Herpes_IE2_3 PF03361.14 EAX67196.1 - 0.0049 16.8 1.7 0.16 11.9 0.3 2.1 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX67196.1 - 0.0068 16.7 4.0 0.6 10.4 0.9 2.4 2 0 0 2 2 2 2 PPP5 TPR repeat region FliG_C PF01706.16 EAX67200.1 - 0.025 14.7 4.1 17 5.7 0.1 3.3 1 1 2 3 3 3 0 FliG C-terminal domain YmaF PF12788.7 EAX67201.1 - 0.0038 17.7 2.3 4.4 7.9 0.0 3.1 3 0 0 3 3 3 2 YmaF family Phage_fiber PF03335.13 EAX67201.1 - 0.036 14.2 12.8 2.5 8.5 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX67201.1 - 0.076 13.1 8.7 0.21 11.7 2.0 3.0 3 1 0 3 3 3 0 Phage tail repeat like KilA-N PF04383.13 EAX67202.1 - 1.3e-42 144.2 0.0 2.6e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX67202.1 - 0.06 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX67203.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain TMP PF05017.14 EAX67206.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2897 PF11446.8 EAX67207.1 - 0.39 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX67208.1 - 3e-49 166.6 5.0 3.3e-49 166.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX67208.1 - 0.12 12.7 0.3 6.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4107 PF13389.6 EAX67209.1 - 3.6e-65 219.0 2.2 4.2e-65 218.8 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67209.1 - 0.098 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX67210.1 - 4.2e-06 26.7 1.1 4.2e-06 26.7 1.1 2.9 3 0 0 3 3 3 1 Phage tail repeat like DNA_pol_B_2 PF03175.13 EAX67211.1 - 6.8e-09 35.1 1.3 9.9e-09 34.6 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX67211.1 - 0.097 12.7 0.0 0.68 10.0 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX67211.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 RGS12_us1 PF16613.5 EAX67212.1 - 0.18 12.1 3.4 0.28 11.5 3.4 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 DUF4108 PF13390.6 EAX67213.1 - 3.9e-55 185.7 6.3 4.3e-55 185.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX67214.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67215.1 - 0.077 12.9 0.9 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2486 PF10667.9 EAX67219.1 - 0.17 12.1 29.4 0.11 12.7 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DUF3839 PF12943.7 EAX67220.1 - 1.8e-131 436.9 14.3 2.3e-131 436.5 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX67220.1 - 0.057 13.7 1.7 0.081 13.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF29 PRD PF00874.20 EAX67220.1 - 0.73 10.2 0.1 0.73 10.2 0.1 3.1 4 0 0 4 4 4 0 PRD domain KELK PF15796.5 EAX67220.1 - 1.2 9.6 6.7 0.91 10.0 0.2 3.1 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX67221.1 - 3.1e-07 30.1 3.7 5.3e-07 29.4 3.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67221.1 - 0.0045 16.6 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67221.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67221.1 - 0.061 13.1 0.1 0.35 10.6 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX67221.1 - 0.081 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX67221.1 - 0.27 11.2 2.0 1.3 9.0 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67221.1 - 0.43 10.8 7.9 5.4 7.2 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Mid2 PF04478.12 EAX67222.1 - 0.00013 21.8 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX67222.1 - 0.00014 21.5 2.0 0.00021 21.0 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX67222.1 - 0.00065 19.8 0.0 0.00081 19.5 0.0 1.1 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX67222.1 - 0.00092 19.1 0.1 0.0011 18.9 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX67222.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Syndecan domain ECSCR PF15820.5 EAX67222.1 - 0.004 17.0 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Glycophorin_A PF01102.18 EAX67222.1 - 0.0046 17.2 2.3 0.0061 16.8 2.3 1.4 1 1 0 1 1 1 1 Glycophorin A DUF3827 PF12877.7 EAX67222.1 - 0.012 14.1 0.0 0.012 14.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 EAX67222.1 - 0.015 14.7 3.6 0.021 14.2 3.6 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 EAX67222.1 - 0.017 14.5 3.7 0.032 13.7 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MMM1 PF10296.9 EAX67222.1 - 0.019 14.0 0.1 0.02 13.9 0.1 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 EphA2_TM PF14575.6 EAX67222.1 - 0.021 15.7 0.0 0.027 15.4 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 EAX67222.1 - 0.03 14.6 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) ODV-E18 PF10717.9 EAX67222.1 - 0.038 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cortexin PF11057.8 EAX67222.1 - 0.042 13.7 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Cortexin of kidney PTP_tm PF18861.1 EAX67222.1 - 0.055 13.5 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Otopetrin PF03189.13 EAX67222.1 - 0.061 12.1 0.0 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 Otopetrin PsbW PF07123.12 EAX67222.1 - 0.074 13.1 0.0 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Gemini_mov PF01708.16 EAX67222.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Geminivirus putative movement protein YukC PF10140.9 EAX67222.1 - 0.097 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF2207 PF09972.9 EAX67222.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM192 PF14802.6 EAX67222.1 - 0.13 11.4 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 TMEM192 family Stevor PF17410.2 EAX67222.1 - 0.18 11.3 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 EAX67222.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF5385 PF17359.2 EAX67222.1 - 0.19 11.3 0.1 0.21 11.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 EAX67222.1 - 0.33 10.7 1.7 0.33 10.7 1.2 1.4 1 1 1 2 2 2 0 African swine fever virus J13L protein FAS_N PF17828.1 EAX67223.1 - 0.0058 16.6 0.2 0.0071 16.4 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX67224.1 - 5.2e-05 23.6 2.9 0.00029 21.3 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX67224.1 - 0.028 13.5 1.0 0.04 13.0 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) ResIII PF04851.15 EAX67228.1 - 4.5e-05 23.5 0.1 5.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX67228.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX67228.1 - 0.002 18.4 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX67228.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX67228.1 - 0.0036 17.6 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67228.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX67228.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX67228.1 - 0.086 12.5 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX67228.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein KilA-N PF04383.13 EAX67230.1 - 1e-25 89.8 1.7 1.2e-25 89.6 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX67230.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX67231.1 - 3.1e-07 30.1 3.3 4.7e-07 29.5 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67231.1 - 0.0042 16.8 0.1 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67231.1 - 0.043 13.3 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67231.1 - 0.059 13.1 0.1 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX67231.1 - 0.08 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX67231.1 - 0.18 11.8 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67231.1 - 0.36 11.0 8.5 5.4 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF1493 PF07377.12 EAX67232.1 - 0.025 15.0 1.0 0.039 14.4 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67232.1 - 0.28 11.3 3.5 6.9 6.8 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PapD_N PF00345.20 EAX67235.1 - 0.031 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX67235.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX67236.1 - 1.1e-22 80.6 4.1 1.5e-22 80.2 4.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ResIII PF04851.15 EAX67238.1 - 3.4e-05 23.9 1.8 6.6e-05 23.0 1.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67238.1 - 0.00029 20.6 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX67238.1 - 0.00039 20.7 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX67238.1 - 0.001 18.9 0.4 0.0022 17.9 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67238.1 - 0.0062 16.9 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67238.1 - 0.034 13.6 0.1 0.077 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX67238.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX67238.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX67238.1 - 0.23 11.2 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67238.1 - 0.48 10.7 5.1 4.1 7.7 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF257 PF03192.13 EAX67239.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67239.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX67240.1 - 3.7e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67240.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67240.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67240.1 - 0.061 13.1 0.1 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67240.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67240.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX67241.1 - 5e-05 23.3 0.3 5e-05 23.3 0.3 4.0 3 1 1 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX67241.1 - 0.0091 15.8 5.5 0.013 15.3 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX67241.1 - 0.036 14.5 2.6 0.13 12.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX67241.1 - 0.14 11.1 1.7 0.23 10.4 1.7 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4795 PF16043.5 EAX67241.1 - 2.7 7.6 15.9 1.1 8.8 6.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAX67242.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Annexin PF00191.20 EAX67245.1 - 0.24 11.5 1.2 1.3 9.2 0.2 2.7 2 1 0 2 2 2 0 Annexin PRA-PH PF01503.17 EAX67245.1 - 0.87 10.1 3.4 3.6 8.1 2.8 2.2 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4106 PF13388.6 EAX67246.1 - 5.8e-17 62.0 2.6 5.8e-17 62.0 2.6 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) VP4_2 PF08935.10 EAX67246.1 - 0.081 13.5 0.7 0.18 12.4 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit ArsC PF03960.15 EAX67246.1 - 8.2 6.5 7.7 0.7 10.0 0.1 3.0 3 1 0 3 3 3 0 ArsC family PSP PF04046.16 EAX67247.1 - 0.35 10.8 3.8 0.24 11.3 0.6 2.4 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX67248.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX67249.1 - 1.6e-20 73.5 10.0 5.7e-20 71.6 10.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4795 PF16043.5 EAX67250.1 - 0.0012 18.4 12.4 0.049 13.2 6.6 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) PTR PF12789.7 EAX67250.1 - 0.041 13.9 2.7 0.041 13.9 2.7 3.4 3 1 0 3 3 3 0 Phage tail repeat like DUF2018 PF09442.10 EAX67250.1 - 0.25 12.4 1.6 0.73 10.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Phage_fiber PF03335.13 EAX67250.1 - 2.9 8.3 7.0 4.6 7.7 1.1 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat TMP PF05017.14 EAX67251.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX67254.1 - 5.7e-08 32.5 0.6 6.9e-08 32.3 0.6 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67254.1 - 0.004 16.8 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67254.1 - 0.073 12.8 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67254.1 - 0.082 12.9 0.4 0.65 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX67256.1 - 0.026 15.0 0.7 0.046 14.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX67257.1 - 7.5e-05 23.2 1.0 0.0008 19.9 0.2 2.3 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX67257.1 - 0.012 14.9 0.1 0.021 14.1 0.0 1.4 2 0 0 2 2 2 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX67257.1 - 0.056 13.0 0.8 0.71 9.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain MULE PF10551.9 EAX67258.1 - 6.1e-12 45.8 0.1 9.8e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain Pox_A32 PF04665.12 EAX67260.1 - 3e-07 30.2 0.1 8.3e-07 28.7 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX67261.1 - 1.1e-64 218.2 3.7 1.5e-64 217.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX67261.1 - 0.15 12.5 0.4 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Antimicrobial_7 PF08102.11 EAX67262.1 - 0.069 13.4 1.6 0.13 12.5 1.3 1.8 1 1 0 1 1 1 0 Scorpion antimicrobial peptide TMP PF05017.14 EAX67263.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67264.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX67266.1 - 2.1e-116 387.6 5.1 2.6e-116 387.3 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DDE_1 PF03184.19 EAX67267.1 - 3.5e-17 62.6 0.1 4.7e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX67267.1 - 1.8e-06 27.7 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease YmaF PF12788.7 EAX67268.1 - 0.051 14.1 1.2 2.3 8.8 0.1 2.0 1 1 0 1 1 1 0 YmaF family KilA-N PF04383.13 EAX67271.1 - 6.3e-28 96.9 0.5 1.4e-27 95.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67271.1 - 0.0065 17.1 0.1 0.014 16.0 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX67272.1 - 7.2e-05 22.4 0.4 8.2e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX67272.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase FAS_N PF17828.1 EAX67273.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta HI0933_like PF03486.14 EAX67273.1 - 0.26 9.9 0.8 0.32 9.6 0.8 1.0 1 0 0 1 1 1 0 HI0933-like protein DUF2939 PF11159.8 EAX67274.1 - 0.0096 16.3 0.4 0.01 16.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) DUF4841 PF16129.5 EAX67275.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DUF4108 PF13390.6 EAX67278.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX67279.1 - 0.7 9.8 3.2 1.4 8.8 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PSP PF04046.16 EAX67280.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP AAA_22 PF13401.6 EAX67281.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67281.1 - 6.9e-05 22.6 0.3 0.25 11.1 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67281.1 - 7.6e-05 22.8 2.9 0.00013 22.0 2.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67281.1 - 0.0004 20.2 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67281.1 - 0.0011 18.8 1.0 0.0043 16.9 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67281.1 - 0.0088 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67281.1 - 0.056 12.9 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67281.1 - 0.072 13.5 0.1 0.42 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX67281.1 - 0.078 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX67281.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67281.1 - 0.29 11.4 4.7 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX67283.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX67284.1 - 6.8e-96 322.0 4.9 6.8e-96 322.0 4.9 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) DUF885 PF05960.11 EAX67284.1 - 0.0006 19.6 2.3 0.00075 19.3 2.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) ArAE_1_C PF11728.8 EAX67284.1 - 0.058 13.4 7.7 0.095 12.7 7.7 1.3 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain FapA PF03961.13 EAX67284.1 - 0.17 10.5 4.2 0.21 10.2 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EAX67284.1 - 2.9 7.9 4.9 2.2 8.3 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2939 PF11159.8 EAX67288.1 - 0.026 14.9 0.2 0.03 14.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX67289.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4106 PF13388.6 EAX67290.1 - 1.1e-89 301.7 4.1 1.8e-89 300.9 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4106 PF13388.6 EAX67291.1 - 2e-17 63.6 35.4 8.7e-11 41.7 9.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX67292.1 - 0.0093 15.6 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4378 PF14309.6 EAX67293.1 - 0.022 15.1 0.0 0.051 14.0 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) DUF3839 PF12943.7 EAX67294.1 - 1.3e-25 90.3 3.8 1.7e-25 89.9 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX67294.1 - 0.047 14.0 0.3 0.14 12.5 0.1 1.8 1 1 1 2 2 2 0 PRD domain DUF3839 PF12943.7 EAX67295.1 - 4.1e-39 134.5 4.2 6.2e-39 133.9 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX67295.1 - 0.046 14.0 0.4 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 PRD domain DDR PF08841.10 EAX67296.1 - 0.042 12.9 0.2 0.043 12.8 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX67298.1 - 1.4e-120 401.3 11.4 1.7e-120 400.9 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67298.1 - 0.012 16.0 2.7 1.8 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX67298.1 - 0.16 12.5 2.1 0.19 12.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) HNH_3 PF13392.6 EAX67299.1 - 1.9e-08 33.9 0.3 3.5e-08 33.1 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease PTR PF12789.7 EAX67301.1 - 1.5e-05 24.9 17.2 6e-05 23.0 0.2 5.5 4 2 2 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX67301.1 - 0.00095 18.8 1.5 0.00095 18.8 1.5 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF4795) DUF4738 PF15889.5 EAX67301.1 - 0.0079 16.0 2.3 0.0079 16.0 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4738) Podoplanin PF05808.11 EAX67301.1 - 0.4 10.8 2.4 10 6.2 0.2 2.2 1 1 1 2 2 2 0 Podoplanin KilA-N PF04383.13 EAX67304.1 - 4.5e-26 90.9 0.2 4.5e-26 90.9 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX67304.1 - 0.0033 17.5 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FAS_N PF17828.1 EAX67305.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX67306.1 - 3.9e-25 88.7 5.0 6.2e-25 88.1 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX67306.1 - 0.03 14.6 0.5 0.1 12.9 0.1 2.0 1 1 1 2 2 2 0 PRD domain GalP_UDP_transf PF01087.22 EAX67306.1 - 0.31 11.5 1.7 9.3 6.6 0.4 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DASH_Dam1 PF08653.10 EAX67307.1 - 0.12 12.2 0.0 0.75 9.6 0.0 2.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 TMP PF05017.14 EAX67309.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX67311.1 - 2.1e-73 246.7 8.7 2.8e-73 246.3 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX67312.1 - 6.1e-26 91.3 8.6 9.4e-26 90.7 8.6 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral VirE PF05272.11 EAX67313.1 - 8.9e-06 25.6 0.1 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX67313.1 - 0.044 12.8 1.9 0.12 11.4 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX67313.1 - 0.076 13.4 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 RNA helicase PSP PF04046.16 EAX67315.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67316.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat ResIII PF04851.15 EAX67317.1 - 4.9e-05 23.4 2.3 9.2e-05 22.5 2.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67317.1 - 0.0003 20.6 0.0 0.00037 20.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX67317.1 - 0.00039 20.7 0.0 0.00068 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX67317.1 - 0.00089 19.1 1.3 0.003 17.4 1.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67317.1 - 0.0066 16.8 0.0 0.009 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67317.1 - 0.027 14.2 0.3 0.17 11.6 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX67317.1 - 0.038 13.4 0.1 0.059 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX67317.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67317.1 - 0.16 12.2 4.4 4.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX67317.1 - 0.82 10.1 4.3 0.33 11.4 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 BRO1 PF03097.18 EAX67319.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX67319.1 - 1.3 9.3 6.3 6.4 7.2 0.7 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat LRR_5 PF13306.6 EAX67320.1 - 3.4e-67 224.3 35.1 1e-29 103.1 9.4 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX67320.1 - 6.4e-16 57.9 1.0 0.00043 20.0 0.5 5.5 3 2 3 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAX67320.1 - 0.0073 16.7 12.3 11 6.6 2.0 5.6 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) DUF1731 PF08338.11 EAX67321.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Amidase02_C PF12123.8 EAX67323.1 - 0.0055 16.4 0.1 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1554 PF07588.11 EAX67325.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) TMP PF05017.14 EAX67325.1 - 5 8.2 7.9 25 6.1 0.8 3.1 3 0 0 3 3 3 0 TMP repeat MULE PF10551.9 EAX67326.1 - 8e-11 42.2 1.2 1.2e-10 41.6 0.3 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX67326.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Pox_A32 PF04665.12 EAX67327.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67327.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67327.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67327.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX67327.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX67327.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67327.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX67328.1 - 7.6e-12 45.1 3.5 7.6e-12 45.1 3.5 4.4 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX67328.1 - 0.032 13.8 7.7 0.032 13.8 5.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX67329.1 - 4.5e-127 422.5 8.0 5.1e-127 422.3 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67329.1 - 0.083 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX67329.1 - 0.25 11.8 1.9 1.7 9.2 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2897 PF11446.8 EAX67331.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX67333.1 - 4.5e-07 29.6 0.0 5.9e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX67334.1 - 8.5e-43 144.8 1.4 1.4e-42 144.1 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX67335.1 - 4.3e-07 29.7 4.5 4.6e-07 29.5 2.9 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX67335.1 - 5.4e-05 23.0 0.2 0.39 10.4 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67335.1 - 5.8e-05 23.4 0.1 0.00038 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67335.1 - 8e-05 22.7 2.8 0.00014 21.9 2.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67335.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX67335.1 - 0.0017 18.0 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX67335.1 - 0.0018 18.1 0.4 0.0031 17.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67335.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67335.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX67335.1 - 0.075 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX67335.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67335.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX67335.1 - 0.44 10.8 3.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX67335.1 - 0.85 10.1 4.8 0.33 11.4 1.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4106 PF13388.6 EAX67336.1 - 6.6e-97 325.4 5.0 7.6e-97 325.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Nucleopor_Nup85 PF07575.13 EAX67337.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Nup85 Nucleoporin T5orf172 PF10544.9 EAX67338.1 - 2.9e-06 27.8 0.2 5.8e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX67339.1 - 9.8e-23 80.7 4.7 1.4e-22 80.3 4.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX67340.1 - 0.052 14.0 0.4 0.13 12.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX67342.1 - 7.6e-32 109.5 0.0 1.1e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain NAD_binding_8 PF13450.6 EAX67343.1 - 0.21 11.8 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DNA_pol_B_2 PF03175.13 EAX67344.1 - 1.8e-21 76.6 4.7 3.1e-21 75.8 4.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67344.1 - 0.067 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Tho2 PF11262.8 EAX67345.1 - 0.047 12.9 1.7 0.051 12.8 1.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX67345.1 - 0.53 10.2 8.3 0.21 11.5 2.9 2.5 3 0 0 3 3 3 0 Spo12 family YmaF PF12788.7 EAX67346.1 - 0.051 14.1 1.2 2.3 8.8 0.1 2.0 1 1 0 1 1 1 0 YmaF family T5orf172 PF10544.9 EAX67347.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain T5orf172 PF10544.9 EAX67348.1 - 6.8e-07 29.8 0.2 1.9e-06 28.3 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Gly-zipper_Omp PF13488.6 EAX67350.1 - 0.0072 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX67350.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX67350.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX67350.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX67350.1 - 3 8.9 0.2 3 8.9 0.2 3.3 4 0 0 4 4 4 0 TMP repeat DUF3839 PF12943.7 EAX67351.1 - 1.7e-119 397.7 6.2 1.9e-119 397.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX67351.1 - 0.11 11.9 0.5 0.13 11.7 0.5 1.3 1 1 0 1 1 1 0 Z1 domain Trns_repr_metal PF02583.17 EAX67351.1 - 0.12 12.8 0.2 6.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor KELK PF15796.5 EAX67351.1 - 0.14 12.6 1.4 1 9.8 0.6 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX67354.1 - 5.8e-09 35.3 1.3 9.5e-09 34.6 1.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX67354.1 - 0.061 12.0 2.8 0.58 8.8 2.8 2.1 1 1 0 1 1 1 0 DNA polymerase family B gpUL132 PF11359.8 EAX67354.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX67354.1 - 0.087 12.8 0.0 0.66 10.0 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor GPS2_interact PF15784.5 EAX67356.1 - 0.091 13.2 1.6 0.12 12.8 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67356.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Glyco_hydro_30C PF17189.4 EAX67357.1 - 6e-08 32.8 2.1 1e-07 32.1 2.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Amidase02_C PF12123.8 EAX67358.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase MULE PF10551.9 EAX67360.1 - 7.5e-10 39.1 3.9 1.4e-09 38.3 3.9 1.4 1 0 0 1 1 1 1 MULE transposase domain Gemini_AL1_M PF08283.11 EAX67360.1 - 0.02 15.0 1.5 0.036 14.1 0.3 2.1 2 0 0 2 2 2 0 Geminivirus rep protein central domain DUF4107 PF13389.6 EAX67361.1 - 5.3e-61 205.5 12.5 7e-59 198.6 12.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67361.1 - 0.1 12.9 0.5 0.14 12.5 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX67362.1 - 4.3e-16 58.8 2.4 5.6e-16 58.5 2.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67362.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Ank_4 PF13637.6 EAX67363.1 - 1.2e-23 83.1 7.3 1e-10 41.9 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX67363.1 - 2.3e-16 60.1 0.2 3.5e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX67363.1 - 1.2e-12 47.8 0.5 7.1e-08 32.6 0.1 2.9 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX67363.1 - 8.7e-12 44.9 4.2 0.0042 17.5 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX67363.1 - 8.8e-11 41.1 2.0 0.0094 16.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat rve PF00665.26 EAX67364.1 - 3.8e-14 52.9 0.1 6.5e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain LBR_tudor PF09465.10 EAX67364.1 - 0.0012 18.6 0.3 0.0029 17.4 0.3 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX67364.1 - 0.0072 16.7 0.3 0.14 12.6 0.1 2.9 1 1 2 3 3 3 1 Spi protease inhibitor GGDEF PF00990.21 EAX67365.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX67365.1 - 8.5 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) VirE PF05272.11 EAX67368.1 - 9e-06 25.5 0.1 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX67368.1 - 0.029 13.4 1.9 0.12 11.4 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX67368.1 - 0.074 13.5 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 RNA helicase DUF4106 PF13388.6 EAX67370.1 - 5e-95 319.2 4.2 8.2e-95 318.5 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Pox_Ag35 PF03286.14 EAX67372.1 - 0.88 9.3 5.9 1.4 8.7 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KilA-N PF04383.13 EAX67373.1 - 9.7e-18 64.1 2.0 1.1e-17 63.9 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67373.1 - 0.003 18.1 0.0 0.0062 17.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX67374.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67374.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67374.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67374.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PSP PF04046.16 EAX67376.1 - 0.064 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67377.1 - 0.085 13.5 6.1 11 7.2 0.3 3.4 3 1 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX67379.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF257 PF03192.13 EAX67380.1 - 0.0044 16.8 0.0 0.0051 16.6 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 T5orf172 PF10544.9 EAX67382.1 - 2.1e-07 31.4 0.3 3.9e-07 30.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain VirE PF05272.11 EAX67384.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX67384.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX67384.1 - 0.088 11.7 0.2 7.6 5.3 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PapD_N PF00345.20 EAX67386.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX67386.1 - 0.11 12.5 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Trypan_PARP PF05887.11 EAX67388.1 - 0.094 12.7 6.5 0.12 12.3 6.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX67388.1 - 3.7 5.1 11.2 4.1 4.9 11.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Mito_fiss_reg PF05308.11 EAX67389.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX67389.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_A32 PF04665.12 EAX67390.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67390.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67390.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67390.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX67390.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX67390.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67390.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3781 PF12636.7 EAX67392.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX67393.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67393.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX67394.1 - 9.9e-157 519.6 14.0 1.2e-156 519.3 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX67394.1 - 0.026 15.0 1.8 0.14 12.6 0.2 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX67394.1 - 0.43 11.1 6.1 0.18 12.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX67394.1 - 0.55 10.7 7.1 2.1 8.9 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX67396.1 - 4.1e-122 406.3 10.5 1.4e-121 404.5 10.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX67397.1 - 0.0019 17.8 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Cwf_Cwc_15 PF04889.12 EAX67399.1 - 0.3 10.8 9.3 0.39 10.4 9.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EAX67399.1 - 2.2 7.3 10.7 2.7 7.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EAX67399.1 - 9.2 5.5 8.9 12 5.1 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_B_2 PF03175.13 EAX67400.1 - 5.5e-30 104.7 5.6 8.4e-30 104.0 5.6 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX67401.1 - 2.5e-11 43.1 0.2 2.5e-11 43.1 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67401.1 - 0.022 14.1 0.3 0.031 13.6 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PSP PF04046.16 EAX67404.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP IstB_IS21 PF01695.17 EAX67405.1 - 1.8e-05 24.6 0.4 0.21 11.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67405.1 - 3e-05 24.3 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67405.1 - 0.00029 20.9 4.6 0.00047 20.2 3.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX67405.1 - 0.0005 19.6 2.3 0.0005 19.6 2.3 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX67405.1 - 0.00051 19.9 0.1 0.00097 19.0 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67405.1 - 0.0018 18.1 1.1 0.0037 17.1 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67405.1 - 0.0045 16.7 3.0 0.012 15.2 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67405.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX67405.1 - 0.057 13.5 0.7 0.91 9.6 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX67405.1 - 0.061 12.9 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67405.1 - 0.068 13.6 0.1 0.67 10.4 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67405.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67405.1 - 0.59 10.4 5.1 7.9 6.8 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX67405.1 - 5.5 7.7 11.7 0.39 11.4 2.4 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 FAS_N PF17828.1 EAX67406.1 - 0.0041 17.1 0.3 0.0054 16.7 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HI0933_like PF03486.14 EAX67406.1 - 0.19 10.4 1.0 0.24 10.1 1.0 1.0 1 0 0 1 1 1 0 HI0933-like protein Tho2 PF11262.8 EAX67407.1 - 0.053 12.7 2.9 0.059 12.6 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PHP_C PF13263.6 EAX67407.1 - 0.096 12.5 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX67407.1 - 0.24 11.3 8.8 0.087 12.7 3.1 2.8 3 1 0 3 3 3 0 Spo12 family DUF257 PF03192.13 EAX67408.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67408.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX67409.1 - 8.7e-05 22.1 4.2 0.00016 21.3 4.2 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67409.1 - 0.0035 17.4 0.2 0.0094 16.0 0.2 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX67409.1 - 0.014 15.0 0.3 0.028 14.0 0.3 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX67409.1 - 0.051 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ACP_PD PF04336.12 EAX67410.1 - 0.085 13.3 0.1 0.45 10.9 0.0 2.2 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase DUF4107 PF13389.6 EAX67411.1 - 1.4e-71 239.9 4.2 1.8e-71 239.6 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ARA70 PF12489.8 EAX67412.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Phage_fiber PF03335.13 EAX67414.1 - 0.17 12.1 4.8 1.8 8.9 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX67414.1 - 0.2 12.2 1.6 1.5 9.4 1.7 2.0 1 1 0 1 1 1 0 YmaF family TMP PF05017.14 EAX67416.1 - 0.046 14.3 4.8 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX67418.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67419.1 - 0.069 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX67420.1 - 0.009 16.0 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX67421.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67421.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67421.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67421.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67421.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67421.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67421.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67421.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67421.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67421.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67421.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67421.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX67422.1 - 1.8e-75 254.8 12.3 1.8e-75 254.8 12.3 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX67422.1 - 1.4 9.3 5.4 0.44 10.9 0.1 2.5 2 1 0 2 2 2 0 Kidney androgen-regulated DUF1493 PF07377.12 EAX67424.1 - 0.068 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FliJ PF02050.16 EAX67426.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein AAA_22 PF13401.6 EAX67428.1 - 5.8e-05 23.4 0.1 0.00034 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67428.1 - 8.9e-05 22.6 3.0 0.00017 21.6 2.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67428.1 - 0.00049 19.9 0.0 0.00078 19.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67428.1 - 0.0014 18.5 1.1 0.0046 16.8 1.2 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67428.1 - 0.0014 18.4 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67428.1 - 0.009 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67428.1 - 0.057 12.9 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX67428.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX67428.1 - 0.12 12.9 0.1 0.46 10.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67428.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67428.1 - 0.22 11.8 4.1 6.2 7.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) FAS_N PF17828.1 EAX67430.1 - 0.017 15.2 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Peptidase_C3G PF12381.8 EAX67430.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase DUF2939 PF11159.8 EAX67431.1 - 0.017 15.5 0.5 0.021 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67431.1 - 1.4 8.9 5.8 1.5 8.8 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX67431.1 - 1.5 7.8 2.7 1.6 7.7 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF1947 PF09183.10 EAX67432.1 - 0.079 13.3 0.1 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) DDE_Tnp_4 PF13359.6 EAX67433.1 - 1.1e-36 125.9 0.0 1.4e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX67433.1 - 9.3e-08 32.0 0.8 1.9e-06 27.7 0.8 2.1 1 1 0 1 1 1 1 Transposase DDE domain UCH PF00443.29 EAX67433.1 - 5.1e-06 26.2 0.8 2.2e-05 24.1 0.3 2.0 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX67433.1 - 0.0026 17.4 0.1 0.064 12.8 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1_2 PF13586.6 EAX67433.1 - 0.094 13.1 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain PTR PF12789.7 EAX67435.1 - 1.3e-32 111.6 17.2 1.3e-32 111.6 17.2 3.1 3 1 1 4 4 4 1 Phage tail repeat like RACo_linker PF17650.1 EAX67435.1 - 0.016 15.1 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 RACo linker region PH_TFIIH PF08567.11 EAX67435.1 - 0.045 14.1 1.8 0.88 9.9 0.3 2.5 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain DUF4107 PF13389.6 EAX67437.1 - 1.3e-67 227.0 2.7 1.7e-67 226.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX67438.1 - 6.5e-07 29.8 0.6 8.9e-06 26.2 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain DUF4107 PF13389.6 EAX67439.1 - 1.8e-72 242.8 3.5 2.4e-72 242.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF257 PF03192.13 EAX67440.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67440.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Trypan_PARP PF05887.11 EAX67441.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX67441.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX67442.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67442.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Meiosis_expr PF15163.6 EAX67443.1 - 0.087 13.5 1.3 0.11 13.1 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed TPR_22 PF18833.1 EAX67443.1 - 0.1 12.8 2.1 0.2 11.8 0.8 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3839 PF12943.7 EAX67445.1 - 2.1e-117 390.8 5.8 2.4e-117 390.7 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67445.1 - 0.46 11.0 2.4 1.2 9.7 0.9 2.5 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ARA70 PF12489.8 EAX67447.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX67450.1 - 5.1e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67450.1 - 0.0061 16.6 0.7 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX67450.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 zf-nanos PF05741.13 EAX67451.1 - 0.17 12.2 0.5 0.25 11.6 0.5 1.4 1 1 0 1 1 1 0 Nanos RNA binding domain YmaF PF12788.7 EAX67451.1 - 0.44 11.1 3.5 4.7 7.8 0.3 2.1 1 1 1 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX67451.1 - 2.5 8.5 7.4 5.9 7.4 0.2 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat tRNA_synt_1c_R1 PF04558.15 EAX67453.1 - 0.0048 16.9 1.2 0.0079 16.2 0.1 1.8 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX67453.1 - 0.017 14.7 0.2 0.029 14.0 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX67453.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 MetW PF07021.12 EAX67454.1 - 0.049 13.2 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Transposase_mut PF00872.18 EAX67455.1 - 0.0011 17.9 0.2 0.0012 17.8 0.2 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX67455.1 - 0.0094 15.9 0.4 0.011 15.7 0.4 1.1 1 0 0 1 1 1 1 Vta1 like DDE_Tnp_ISL3 PF01610.17 EAX67455.1 - 0.021 14.5 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 Transposase MULE PF10551.9 EAX67455.1 - 0.13 12.7 0.4 0.36 11.3 0.1 1.9 2 0 0 2 2 2 0 MULE transposase domain DUF4106 PF13388.6 EAX67458.1 - 1.3e-153 512.2 31.1 1.8e-152 508.4 31.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) DUF1493 PF07377.12 EAX67459.1 - 0.057 13.9 0.4 0.11 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67459.1 - 0.4 10.7 3.4 9 6.4 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3781 PF12636.7 EAX67460.1 - 0.031 14.2 1.3 0.049 13.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX67461.1 - 1.3e-67 227.0 2.7 1.7e-67 226.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1731 PF08338.11 EAX67462.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TMP PF05017.14 EAX67463.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67464.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP 2_5_RNA_ligase2 PF13563.6 EAX67465.1 - 0.03 14.2 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Col_cuticle_N PF01484.17 EAX67465.1 - 0.14 12.2 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF3839 PF12943.7 EAX67466.1 - 2e-155 515.3 12.4 2.3e-155 515.1 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67466.1 - 0.14 12.0 0.9 0.46 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX67466.1 - 3.6 8.1 7.7 1.5 9.3 0.8 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX67467.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67468.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Ank_4 PF13637.6 EAX67469.1 - 2.3e-07 31.2 0.0 2.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX67469.1 - 0.00047 20.7 0.1 0.00079 20.0 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX67469.1 - 0.0013 19.1 0.1 0.46 11.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX67469.1 - 0.0015 18.8 0.0 0.88 10.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX67469.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) YvrJ PF12841.7 EAX67470.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Pox_D5 PF03288.16 EAX67472.1 - 3.5e-06 27.4 1.8 1.9e-05 25.1 1.8 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67472.1 - 0.0045 17.6 0.1 0.0087 16.7 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67472.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2897 PF11446.8 EAX67473.1 - 0.25 11.2 3.3 0.3 11.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Vir_act_alpha_C PF10400.9 EAX67474.1 - 0.17 12.6 1.4 0.23 12.2 0.5 1.6 2 0 0 2 2 2 0 Virulence activator alpha C-term CDC45 PF02724.14 EAX67475.1 - 0.062 11.6 16.9 0.075 11.3 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nab1 PF04902.12 EAX67476.1 - 0.031 14.7 1.1 0.034 14.5 1.1 1.0 1 0 0 1 1 1 0 Conserved region in Nab1 SOBP PF15279.6 EAX67477.1 - 0.086 13.4 11.7 0.11 13.1 11.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP54 PF00448.22 EAX67477.1 - 0.17 11.5 1.4 3.3 7.3 0.2 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Peptidase_S64 PF08192.11 EAX67477.1 - 0.43 9.0 13.1 0.52 8.7 13.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Staufen_C PF16482.5 EAX67477.1 - 1.6 8.9 10.4 0.39 10.9 1.4 3.1 1 1 2 3 3 3 0 Staufen C-terminal domain DUF4107 PF13389.6 EAX67478.1 - 7.7e-72 240.7 3.1 1e-71 240.4 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67478.1 - 0.073 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TMP PF05017.14 EAX67479.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67480.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3781 PF12636.7 EAX67481.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX67482.1 - 4.8e-07 29.5 2.3 4.8e-07 29.5 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67482.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67482.1 - 5.7e-05 22.9 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67482.1 - 0.00019 21.5 3.7 0.00042 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67482.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67482.1 - 0.0017 18.2 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67482.1 - 0.0019 17.9 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67482.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67482.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67482.1 - 0.09 13.2 0.1 0.76 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67482.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67482.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX67484.1 - 2.2e-42 143.4 0.6 4.8e-42 142.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX67484.1 - 1.5 8.8 4.9 2.5 8.1 0.4 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF846 PF05832.12 EAX67485.1 - 0.057 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) KilA-N PF04383.13 EAX67486.1 - 4.7e-33 113.4 0.8 9.6e-33 112.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX67487.1 - 3.2e-23 82.4 4.7 4e-23 82.0 4.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX67489.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX67489.1 - 0.047 13.7 0.4 0.069 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX67489.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4106 PF13388.6 EAX67490.1 - 1.2e-130 436.5 18.2 1.9e-130 435.9 18.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX67491.1 - 1.6e-156 518.9 13.7 1.9e-156 518.7 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67491.1 - 0.057 13.3 0.9 0.25 11.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX67491.1 - 0.086 13.1 0.8 1.3 9.3 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX67491.1 - 0.11 13.0 0.4 0.95 9.9 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX67491.1 - 1.3 9.6 7.9 1.9 9.0 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX67492.1 - 0.0029 17.3 0.0 0.0083 15.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX67493.1 - 1e-154 513.0 12.8 1.2e-154 512.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67493.1 - 0.12 12.2 0.9 0.42 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX67493.1 - 0.98 9.9 5.0 1.9 9.0 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX67494.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67494.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67494.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67494.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Trypan_PARP PF05887.11 EAX67499.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX67500.1 - 5.9e-71 237.9 4.1 9e-71 237.3 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX67501.1 - 7.4e-08 32.1 3.2 9.1e-08 31.8 3.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67501.1 - 0.0012 18.6 0.3 0.0013 18.4 0.3 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX67501.1 - 0.029 14.4 1.1 0.079 13.0 0.9 1.8 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF3783 PF12646.7 EAX67501.1 - 0.057 13.4 0.5 0.48 10.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Amidase02_C PF12123.8 EAX67502.1 - 0.0032 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX67505.1 - 2.5e-58 196.1 7.7 2.7e-58 195.9 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX67506.1 - 2.1e-05 24.9 3.7 0.00029 21.3 3.7 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67506.1 - 0.051 14.2 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67506.1 - 0.096 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_15 PF12324.8 EAX67507.1 - 0.33 10.9 5.4 28 4.8 0.1 3.5 2 1 2 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase HEAT PF02985.22 EAX67507.1 - 8.2 7.0 9.4 2.4e+02 2.5 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat DUF1493 PF07377.12 EAX67508.1 - 0.077 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX67509.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67510.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat IstB_IS21 PF01695.17 EAX67511.1 - 2.3e-06 27.5 0.3 0.02 14.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67511.1 - 3.1e-06 27.5 0.2 2.5e-05 24.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX67511.1 - 5.6e-05 22.7 2.0 5.6e-05 22.7 2.0 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX67511.1 - 0.00024 21.1 3.6 0.00051 20.1 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67511.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX67511.1 - 0.0013 18.4 0.3 0.011 15.4 0.1 2.2 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX67511.1 - 0.0014 18.5 0.4 0.0039 17.0 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67511.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX67511.1 - 0.036 13.6 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX67511.1 - 0.036 14.5 0.1 0.62 10.5 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67511.1 - 0.074 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EAX67511.1 - 0.087 11.7 0.0 0.64 8.9 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 EAX67511.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67511.1 - 1.6 9.0 5.4 16 5.8 0.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX67511.1 - 7.2 7.3 10.1 0.72 10.5 1.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DNA_pol_B_2 PF03175.13 EAX67512.1 - 6.5e-16 58.3 1.0 1.3e-15 57.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67512.1 - 0.047 13.0 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein TMP PF05017.14 EAX67513.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX67515.1 - 1.8e-109 364.9 7.9 2e-109 364.7 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67515.1 - 0.21 12.1 1.5 0.8 10.2 1.5 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX67516.1 - 5e-51 170.6 31.9 1.2e-33 114.9 16.2 4.6 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX67516.1 - 0.021 14.5 1.1 0.037 13.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX67516.1 - 0.3 11.5 3.1 5.1 7.5 0.2 3.3 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain Pox_A32 PF04665.12 EAX67517.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX67518.1 - 5.1e-07 29.4 2.1 5.1e-07 29.4 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67518.1 - 3.5e-05 24.1 0.2 0.00027 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67518.1 - 5.9e-05 22.9 0.3 0.4 10.4 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67518.1 - 0.00019 21.5 3.2 0.00035 20.6 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67518.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67518.1 - 0.0016 18.2 0.5 0.0031 17.3 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67518.1 - 0.0023 17.6 0.4 0.015 14.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67518.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX67518.1 - 0.082 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX67518.1 - 0.086 12.4 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX67518.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67518.1 - 0.12 12.8 0.1 0.91 9.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX67518.1 - 0.46 10.8 3.9 12 6.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX67519.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX67520.1 - 0.015 15.7 0.7 0.029 14.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX67521.1 - 9.6e-06 25.6 8.0 1.4e-05 25.0 0.6 3.0 3 0 0 3 3 3 1 Phage tail repeat like Kinetochor_Ybp2 PF08568.10 EAX67521.1 - 0.044 12.3 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin YmaF PF12788.7 EAX67521.1 - 0.13 12.8 2.4 1 10.0 0.9 2.5 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX67521.1 - 3.9 7.9 9.7 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat PSP PF04046.16 EAX67522.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX67523.1 - 8e-52 175.0 5.3 8.8e-52 174.8 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX67524.1 - 1.5e-05 25.4 2.9 8e-05 23.1 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67524.1 - 0.03 14.9 0.1 0.059 14.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67524.1 - 0.089 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_D5 PF03288.16 EAX67525.1 - 1.2e-05 25.7 0.7 1.9e-05 25.1 0.7 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67525.1 - 0.014 16.1 0.2 0.018 15.6 0.2 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67525.1 - 0.052 13.5 0.3 0.076 13.0 0.3 1.3 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX67526.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX67527.1 - 0.47 10.8 2.6 0.52 10.7 2.6 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pox_A32 PF04665.12 EAX67529.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX67530.1 - 0.025 15.0 0.4 0.054 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67530.1 - 0.12 12.4 1.1 7.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4108 PF13390.6 EAX67532.1 - 3.1e-62 208.7 5.7 3.5e-62 208.6 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX67534.1 - 0.007 16.0 0.1 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Retinin_C PF04527.12 EAX67535.1 - 0.00016 21.9 45.5 11 6.4 0.5 8.3 8 0 0 8 8 8 8 Drosophila Retinin like protein Phage_holin_6_1 PF09682.10 EAX67535.1 - 0.014 15.9 10.4 1e+02 3.4 0.2 6.3 1 1 6 7 7 7 0 Bacteriophage holin of superfamily 6 (Holin_LLH) FliG_C PF01706.16 EAX67535.1 - 0.076 13.2 23.7 58 3.9 0.1 7.6 1 1 7 8 8 8 0 FliG C-terminal domain DUF4359 PF14271.6 EAX67535.1 - 0.48 11.2 30.3 27 5.6 1.3 6.7 1 1 6 7 7 7 0 Domain of unknown function (DUF4359) Pro_dh-DNA_bdg PF14850.6 EAX67535.1 - 0.61 10.6 24.6 6.5 7.3 1.1 4.2 1 1 3 4 4 4 0 DNA-binding domain of Proline dehydrogenase UK PF02512.14 EAX67535.1 - 3.8 8.1 31.8 62 4.2 0.5 7.7 1 1 7 8 8 8 0 Virulence determinant PTR PF12789.7 EAX67536.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.5 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX67536.1 - 0.28 11.7 3.3 2.8 8.5 1.5 2.7 2 1 0 2 2 2 0 YmaF family Pox_A32 PF04665.12 EAX67537.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX67539.1 - 6.5e-25 87.9 6.1 7e-25 87.8 6.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5446 PF17522.2 EAX67540.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4107 PF13389.6 EAX67541.1 - 2.5e-45 154.5 1.0 2.9e-45 154.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX67542.1 - 1.6e-20 73.4 4.2 2.6e-20 72.7 4.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX67543.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX67544.1 - 9.8e-07 28.5 2.9 9.8e-07 28.5 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67544.1 - 3.1e-05 24.3 0.2 0.00024 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67544.1 - 4.7e-05 23.2 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67544.1 - 0.00015 21.8 3.3 0.00038 20.5 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67544.1 - 0.00064 19.5 0.1 0.0013 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67544.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67544.1 - 0.0019 17.9 0.4 0.015 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67544.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67544.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67544.1 - 0.075 13.5 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67544.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67544.1 - 0.42 10.9 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX67545.1 - 1.7e-10 40.4 3.0 1.4e-09 37.4 2.3 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67545.1 - 0.097 12.9 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX67545.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DNA_pol_B_2 PF03175.13 EAX67547.1 - 7.3e-15 54.8 4.6 8.5e-14 51.3 4.2 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67547.1 - 0.098 12.9 0.0 0.28 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX67547.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 HTH_11 PF08279.12 EAX67548.1 - 0.15 12.0 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX67548.1 - 0.67 10.0 3.6 0.67 10.0 0.6 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5065) HeH PF12949.7 EAX67549.1 - 1e-05 25.1 11.8 76 3.1 0.0 8.1 8 0 0 8 8 8 8 HeH/LEM domain DUF3839 PF12943.7 EAX67550.1 - 3.9e-134 445.6 13.6 1.1e-133 444.1 13.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX67550.1 - 0.039 14.4 0.5 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX67550.1 - 0.052 14.0 2.1 0.09 13.2 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX67550.1 - 0.28 11.7 9.1 0.77 10.3 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX67550.1 - 0.31 11.6 3.6 0.26 11.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) PSP PF04046.16 EAX67552.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67553.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX67555.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX67555.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX67555.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX67555.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX67556.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX67557.1 - 0.028 14.5 1.8 0.028 14.5 1.8 3.8 5 1 0 5 5 5 0 Phage tail repeat like DUF4795 PF16043.5 EAX67557.1 - 1.1 8.9 6.8 6.7 6.3 5.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX67557.1 - 4.2 7.8 16.2 4 7.9 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX67558.1 - 1.5e-58 198.1 2.7 1.7e-58 197.9 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX67558.1 - 0.047 14.3 0.9 0.18 12.5 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Fe-ADH PF00465.19 EAX67559.1 - 5.9e-31 107.6 0.0 6.6e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX67559.1 - 5.4e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Hist_deacetyl PF00850.19 EAX67559.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 1 1 2 2 2 0 Histone deacetylase domain TMP PF05017.14 EAX67561.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67562.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67563.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX67564.1 - 0.049 14.1 0.5 0.1 13.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX67566.1 - 2.4e-07 30.5 2.1 2.6e-07 30.4 1.6 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67566.1 - 0.0061 16.2 0.1 0.0079 15.8 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX67566.1 - 0.057 13.2 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX67566.1 - 0.076 12.7 0.1 0.26 11.0 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67566.1 - 0.14 12.2 1.9 1.3 9.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX67566.1 - 0.15 12.5 2.2 0.21 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 KilA-N PF04383.13 EAX67567.1 - 1.9e-28 98.6 0.9 3.5e-28 97.7 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67567.1 - 0.046 14.3 0.1 0.12 13.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX67568.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX67568.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Trypan_PARP PF05887.11 EAX67569.1 - 0.073 13.0 10.9 0.098 12.6 10.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX67570.1 - 0.04 14.4 0.5 0.047 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX67572.1 - 0.031 14.3 12.6 0.032 14.2 12.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GGDEF PF00990.21 EAX67574.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX67575.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Transposase_mut PF00872.18 EAX67576.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family KilA-N PF04383.13 EAX67577.1 - 1.9e-41 140.4 0.3 4.1e-41 139.3 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX67577.1 - 0.19 11.7 2.4 0.89 9.6 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein PhaP_Bmeg PF09602.10 EAX67579.1 - 0.052 13.5 0.1 0.6 10.0 0.1 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PHM7_cyt PF14703.6 EAX67579.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Homez PF11569.8 EAX67579.1 - 0.22 11.0 0.5 0.44 10.1 0.5 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_32 PF13565.6 EAX67580.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Gly-zipper_Omp PF13488.6 EAX67582.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX67582.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF4106 PF13388.6 EAX67583.1 - 3e-96 323.2 3.7 3.5e-96 323.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX67584.1 - 0.071 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX67585.1 - 0.004 16.8 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Glyco_trans_1_3 PF13528.6 EAX67586.1 - 0.0036 16.6 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 tRNA_synt_1c_R1 PF04558.15 EAX67586.1 - 0.005 16.9 1.2 0.0074 16.3 0.1 1.7 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX67586.1 - 0.016 14.8 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3839 PF12943.7 EAX67587.1 - 4.4e-78 262.1 9.1 5.8e-78 261.7 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX67587.1 - 0.14 12.5 1.0 0.28 11.5 0.8 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 NTP_transf_6 PF06042.11 EAX67587.1 - 0.2 11.5 1.4 0.66 9.8 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX67588.1 - 4.7e-06 27.1 0.1 1.1e-05 25.9 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX67588.1 - 0.006 16.4 1.3 0.025 14.4 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain DUF846 PF05832.12 EAX67589.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF2939 PF11159.8 EAX67590.1 - 0.018 15.4 0.5 0.027 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67590.1 - 2.4 8.2 5.5 2.5 8.1 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3781 PF12636.7 EAX67591.1 - 0.017 15.0 1.4 0.026 14.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX67592.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67592.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX67593.1 - 0.3 11.1 10.6 0.32 11.0 10.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX67593.1 - 4.8 7.6 6.1 5.5 7.4 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2897 PF11446.8 EAX67595.1 - 1.7 8.6 4.8 3.5 7.6 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX67596.1 - 2.3e-57 192.9 4.2 2.6e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX67597.1 - 0.097 12.8 0.3 0.14 12.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Collagen_mid PF15984.5 EAX67599.1 - 0.064 13.0 0.3 0.07 12.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region TMP PF05017.14 EAX67599.1 - 0.42 11.4 2.5 12 7.2 0.1 3.3 2 2 1 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX67599.1 - 4.8 7.2 8.2 5 7.1 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UCH PF00443.29 EAX67601.1 - 1.3e-14 54.3 0.7 1.9e-14 53.8 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX67601.1 - 0.0031 17.1 1.5 0.0031 17.1 1.5 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX67601.1 - 0.0032 17.0 0.7 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase KilA-N PF04383.13 EAX67603.1 - 3.5e-26 91.2 0.7 6.9e-26 90.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67603.1 - 0.021 15.4 0.0 0.054 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family YmaF PF12788.7 EAX67604.1 - 3.1 8.4 5.4 21 5.7 0.2 2.9 2 1 0 3 3 3 0 YmaF family PSP PF04046.16 EAX67605.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ResIII PF04851.15 EAX67606.1 - 4.8e-05 23.4 2.6 9.6e-05 22.4 2.6 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67606.1 - 0.00032 20.5 0.0 0.00041 20.2 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX67606.1 - 0.00038 20.7 0.0 0.00064 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX67606.1 - 0.00081 19.2 1.1 0.0028 17.5 1.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67606.1 - 0.0067 16.8 0.0 0.0088 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67606.1 - 0.023 14.4 0.2 0.15 11.8 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX67606.1 - 0.037 13.5 0.1 0.055 12.9 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67606.1 - 0.11 12.7 5.1 1.9 8.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX67606.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX67606.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX67609.1 - 3.6e-39 133.9 0.9 4e-39 133.8 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX67609.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PSP PF04046.16 EAX67611.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX67612.1 - 7.7e-05 22.3 0.4 7.8e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX67612.1 - 0.093 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX67613.1 - 1e-07 31.7 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX67614.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX67614.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX67614.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX67614.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX67614.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PSP PF04046.16 EAX67615.1 - 0.078 12.9 0.8 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67616.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Nab1 PF04902.12 EAX67617.1 - 0.04 14.3 1.5 0.063 13.7 1.5 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 TMP PF05017.14 EAX67618.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67619.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67622.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX67622.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.13 EAX67625.1 - 5.4e-10 38.7 0.1 1.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67625.1 - 0.011 15.1 0.7 0.016 14.5 0.7 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DNA_pol_B_2 PF03175.13 EAX67626.1 - 7.1e-22 77.9 4.9 9e-22 77.6 4.9 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67626.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX67628.1 - 1.9e-07 30.8 0.7 1.6e-06 27.8 0.0 2.3 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX67628.1 - 0.054 13.1 0.1 1.1 8.8 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX67628.1 - 0.087 12.7 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX67628.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX67629.1 - 4e-149 494.7 16.8 4.8e-149 494.4 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX67629.1 - 0.0036 16.7 0.4 0.0036 16.7 0.4 1.7 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) NTP_transf_6 PF06042.11 EAX67629.1 - 0.015 15.2 1.1 0.036 13.9 0.4 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX67629.1 - 0.068 13.6 0.4 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX67629.1 - 0.3 11.6 5.7 1.6 9.3 0.3 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX67629.1 - 0.5 10.9 5.9 0.21 12.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 EAX67629.1 - 0.76 10.1 3.9 0.32 11.3 0.5 2.2 2 2 0 2 2 2 0 Tho complex subunit 7 DUF3839 PF12943.7 EAX67630.1 - 5e-148 491.1 13.0 6.4e-148 490.7 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX67630.1 - 0.013 16.0 0.3 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX67630.1 - 0.14 11.7 0.4 0.59 9.6 0.1 2.1 2 1 1 3 3 3 0 SLOG cluster2 GCN5L1 PF06320.13 EAX67630.1 - 0.15 12.2 1.8 0.46 10.6 0.1 2.4 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Rx_N PF18052.1 EAX67630.1 - 0.23 11.8 4.4 1.3 9.4 0.0 3.3 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX67630.1 - 0.24 11.9 5.4 1.6 9.3 0.8 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase JMY PF15871.5 EAX67631.1 - 0.0078 15.6 0.7 0.0099 15.2 0.7 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF4108 PF13390.6 EAX67632.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX67633.1 - 5.8e-05 23.5 2.4 0.00032 21.1 2.4 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67633.1 - 0.043 14.4 0.1 0.09 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67633.1 - 0.099 12.6 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain TMP PF05017.14 EAX67634.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX67635.1 - 9.2e-07 28.6 2.8 9.2e-07 28.6 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67635.1 - 4.6e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67635.1 - 0.00017 21.4 0.3 0.45 10.2 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67635.1 - 0.00031 20.8 3.9 0.00051 20.1 2.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67635.1 - 0.00081 19.2 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67635.1 - 0.0015 18.4 0.5 0.003 17.4 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67635.1 - 0.0062 16.2 2.8 0.014 15.0 0.5 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67635.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67635.1 - 0.086 12.4 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX67635.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67635.1 - 0.11 13.0 0.1 0.92 9.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX67635.1 - 0.12 12.4 0.5 1.3 9.1 0.5 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX67635.1 - 1.1 9.9 11.3 0.57 10.9 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Pox_A32 PF04665.12 EAX67636.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67636.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67636.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67636.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX67638.1 - 4.2e-07 30.4 0.3 8.5e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX67639.1 - 4.2e-05 23.5 0.1 4.2e-05 23.5 0.1 3.0 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX67639.1 - 0.055 12.3 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX67639.1 - 0.3 11.7 3.7 18 5.9 0.1 3.1 2 1 0 2 2 2 0 YmaF family DUF4106 PF13388.6 EAX67640.1 - 6.9e-188 625.1 25.1 2.7e-187 623.1 25.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX67640.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Pox_D5 PF03288.16 EAX67641.1 - 4.2e-05 23.9 2.5 0.00026 21.4 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DNA_pol_B_2 PF03175.13 EAX67642.1 - 6.1e-11 41.8 3.2 5.1e-10 38.8 2.4 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67642.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX67644.1 - 3.9e-158 524.2 12.7 4.9e-158 523.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX67644.1 - 0.027 14.9 1.9 0.059 13.8 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX67644.1 - 0.4 11.2 6.3 1.9 9.0 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX67644.1 - 5.4 7.4 8.3 11 6.4 0.1 3.9 4 2 1 5 5 5 0 Tup N-terminal PSP PF04046.16 EAX67645.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67646.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX67647.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX67648.1 - 1.4e-22 80.2 4.0 1.8e-22 79.9 4.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_22 PF13401.6 EAX67649.1 - 6.2e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67649.1 - 7.1e-05 22.9 3.0 0.00014 21.9 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67649.1 - 0.00042 20.1 0.0 0.00055 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67649.1 - 0.00074 19.4 0.8 0.0021 17.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67649.1 - 0.0068 16.2 0.3 0.27 10.9 0.0 2.5 1 1 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67649.1 - 0.0075 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67649.1 - 0.048 13.1 0.1 0.068 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX67649.1 - 0.083 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX67649.1 - 0.1 13.0 0.0 0.36 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67649.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67649.1 - 0.21 11.8 4.4 5.2 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX67651.1 - 0.028 14.9 0.9 0.056 13.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1731 PF08338.11 EAX67652.1 - 0.23 11.3 0.1 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) AAA_6 PF12774.7 EAX67655.1 - 7.1e-56 189.5 0.2 8e-56 189.4 0.2 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EAX67655.1 - 5.4e-05 23.2 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EAX67655.1 - 0.00022 21.6 0.0 0.00031 21.2 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX67655.1 - 0.0036 17.7 0.3 0.017 15.5 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAX67655.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAX67655.1 - 0.0091 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EAX67655.1 - 0.016 15.8 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX67655.1 - 0.018 15.3 0.1 0.046 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX67655.1 - 0.086 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX67656.1 - 7.7e-21 74.6 4.1 1.1e-20 74.1 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX67656.1 - 0.039 14.3 0.3 0.13 12.5 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX67656.1 - 0.13 12.7 1.5 0.5 10.9 1.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX67657.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67657.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67657.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67657.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) CHORD PF04968.12 EAX67658.1 - 0.021 15.6 0.5 0.032 15.0 0.5 1.3 1 0 0 1 1 1 0 CHORD Ribosomal_S18 PF01084.20 EAX67658.1 - 0.064 13.5 0.1 0.15 12.3 0.0 1.6 1 1 1 2 2 2 0 Ribosomal protein S18 PapD_N PF00345.20 EAX67660.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX67660.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX67661.1 - 5.9e-25 87.1 12.1 5.9e-25 87.1 12.1 3.0 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX67661.1 - 0.074 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain HOCHOB PF17943.1 EAX67662.1 - 2.1 9.1 6.8 3.6 8.3 0.6 2.8 2 2 1 3 3 3 0 Homeobox-cysteine loop-homeobox KilA-N PF04383.13 EAX67664.1 - 9.9e-36 122.0 0.7 1.8e-35 121.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67664.1 - 0.007 17.0 0.1 0.019 15.6 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX67664.1 - 0.63 10.1 4.1 3.3 7.8 0.4 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF257 PF03192.13 EAX67665.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67665.1 - 0.084 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3839 PF12943.7 EAX67666.1 - 2e-143 476.0 16.5 2.4e-143 475.8 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67666.1 - 0.12 12.9 5.7 1.6 9.2 0.1 3.5 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX67666.1 - 0.24 11.8 3.0 14 6.1 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX67666.1 - 0.28 11.8 4.3 0.31 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX67667.1 - 0.045 13.8 3.0 0.045 13.8 3.0 3.1 3 1 0 3 3 3 0 Phage tail repeat like DUF4795 PF16043.5 EAX67667.1 - 0.25 10.9 0.7 0.49 10.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) IstB_IS21 PF01695.17 EAX67668.1 - 2.5e-05 24.1 0.3 0.29 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67668.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX67668.1 - 6.4e-05 22.5 2.2 6.4e-05 22.5 2.2 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX67668.1 - 0.00034 20.6 4.7 0.00067 19.7 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67668.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67668.1 - 0.0018 18.1 1.1 0.0032 17.3 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67668.1 - 0.0038 16.9 2.7 0.014 15.0 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67668.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX67668.1 - 0.063 13.3 0.7 0.99 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX67668.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67668.1 - 0.072 13.5 0.1 0.7 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67668.1 - 0.093 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67668.1 - 0.6 10.4 4.9 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX67668.1 - 4 8.2 11.0 0.28 11.9 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 FAS_N PF17828.1 EAX67669.1 - 0.0064 16.5 0.2 0.0086 16.1 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX67670.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX67671.1 - 3e-09 36.3 2.8 1.3e-08 34.2 2.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX67671.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX67671.1 - 0.13 12.3 0.0 0.87 9.6 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF2939 PF11159.8 EAX67673.1 - 0.017 15.5 0.4 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67673.1 - 1.6 8.8 5.4 1.7 8.7 5.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX67674.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX67675.1 - 0.0037 16.9 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX67676.1 - 1.5e-09 37.8 1.5 1.5e-09 37.8 1.5 3.7 4 1 0 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX67676.1 - 0.011 15.3 1.7 0.011 15.3 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FAS_N PF17828.1 EAX67677.1 - 0.0083 16.1 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX67678.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67678.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 YmaF PF12788.7 EAX67680.1 - 0.16 12.6 1.5 6 7.5 0.1 2.1 1 1 0 1 1 1 0 YmaF family Mid2 PF04478.12 EAX67681.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX67681.1 - 0.00088 19.0 1.9 0.0015 18.3 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX67681.1 - 0.0014 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX67681.1 - 0.0036 17.6 0.3 0.093 13.0 0.2 2.3 2 1 0 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 EAX67681.1 - 0.0056 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX67681.1 - 0.0071 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX67681.1 - 0.0094 16.2 0.6 0.017 15.3 0.6 1.6 1 1 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 EAX67681.1 - 0.048 13.4 0.1 0.072 12.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX67681.1 - 0.05 13.4 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF3827 PF12877.7 EAX67681.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 EAX67681.1 - 0.077 13.9 0.1 0.25 12.3 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 EAX67681.1 - 0.079 12.4 3.5 0.14 11.6 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MMM1 PF10296.9 EAX67681.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ABC2_membrane_3 PF12698.7 EAX67681.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PTP_tm PF18861.1 EAX67681.1 - 0.14 12.2 0.9 0.33 10.9 0.4 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Gemini_mov PF01708.16 EAX67681.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Cortexin PF11057.8 EAX67681.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 Cortexin of kidney Otopetrin PF03189.13 EAX67681.1 - 0.23 10.2 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Otopetrin SKG6 PF08693.10 EAX67681.1 - 0.49 9.9 5.7 0.91 9.0 5.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HD_2 PF12917.7 EAX67682.1 - 0.099 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme T5orf172 PF10544.9 EAX67683.1 - 0.0017 18.9 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX67683.1 - 0.053 13.4 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain KilA-N PF04383.13 EAX67684.1 - 3.5e-42 142.8 0.9 6.2e-42 142.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain PapD_N PF00345.20 EAX67685.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain KilA-N PF04383.13 EAX67686.1 - 4.9e-07 29.6 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain DUF4106 PF13388.6 EAX67687.1 - 4.8e-159 530.1 21.5 7.8e-159 529.4 21.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX67687.1 - 0.00025 21.3 0.1 0.017 15.4 0.3 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX67687.1 - 0.091 13.4 0.7 0.22 12.1 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX67687.1 - 0.12 12.7 6.4 4.3 7.8 0.4 3.5 3 0 0 3 3 3 0 WYL domain JMY PF15871.5 EAX67688.1 - 0.011 15.1 0.7 0.015 14.6 0.7 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX67689.1 - 9.3e-07 29.3 0.3 2.3e-06 28.1 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX67689.1 - 0.13 11.8 0.5 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain PSP PF04046.16 EAX67690.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67691.1 - 0.15 12.8 5.8 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX67693.1 - 2.6e-05 24.6 2.6 0.0002 21.8 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67693.1 - 0.052 14.2 0.1 0.091 13.4 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67693.1 - 0.12 12.3 0.4 0.2 11.7 0.4 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX67694.1 - 0.00015 22.3 0.2 0.00022 21.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX67694.1 - 0.0004 20.8 1.6 0.00067 20.1 1.6 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX67694.1 - 0.048 13.6 0.8 0.075 13.0 0.1 1.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain T5orf172 PF10544.9 EAX67696.1 - 4.9e-07 30.2 0.6 7.6e-06 26.4 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX67696.1 - 0.0082 15.4 0.1 0.015 14.6 0.0 1.5 1 1 1 2 2 2 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX67696.1 - 0.046 13.2 0.6 0.3 10.6 0.2 1.9 2 0 0 2 2 2 0 Legume lectin domain Mito_fiss_reg PF05308.11 EAX67697.1 - 0.04 14.0 1.2 0.043 13.9 1.2 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX67697.1 - 0.58 9.6 5.7 0.6 9.6 5.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2939 PF11159.8 EAX67699.1 - 0.088 13.2 0.1 0.088 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX67700.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX67700.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal PSP PF04046.16 EAX67702.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX67705.1 - 3.5e-61 205.3 7.8 3.9e-61 205.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) CooT PF10133.9 EAX67706.1 - 0.079 13.2 0.2 0.44 10.9 0.1 2.0 1 1 1 2 2 2 0 CO dehydrogenase accessory protein CooT Tetraspanin PF00335.20 EAX67707.1 - 9.6e-09 35.3 0.3 1.1e-08 35.0 0.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3611 PF12263.8 EAX67707.1 - 0.034 14.0 0.3 0.046 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF2897 PF11446.8 EAX67708.1 - 1.2 9.1 4.9 2.5 8.1 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX67709.1 - 3.5e-56 189.1 6.4 3.9e-56 188.9 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX67709.1 - 0.11 12.8 0.1 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Scorpion antimicrobial peptide MG2 PF01835.19 EAX67710.1 - 3e-05 24.4 0.4 0.0047 17.3 0.1 2.7 2 1 0 2 2 2 1 MG2 domain DUF4625 PF15418.6 EAX67710.1 - 0.00011 22.4 1.5 0.019 15.2 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX67710.1 - 0.006 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain NPCBM_assoc PF10633.9 EAX67710.1 - 0.012 15.9 4.2 0.063 13.5 0.2 3.4 2 2 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2914 PF11141.8 EAX67710.1 - 0.028 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) RIFIN PF02009.16 EAX67710.1 - 0.09 12.7 7.2 0.12 12.2 7.2 1.2 1 0 0 1 1 1 0 Rifin PKD PF00801.20 EAX67710.1 - 0.093 12.6 0.3 0.57 10.1 0.1 2.4 2 1 0 2 2 2 0 PKD domain He_PIG PF05345.12 EAX67710.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.8 3 0 0 3 3 3 0 Putative Ig domain KilA-N PF04383.13 EAX67711.1 - 1.6e-42 143.9 0.9 3.2e-42 142.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX67711.1 - 0.022 14.9 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX67711.1 - 0.25 9.8 0.1 0.39 9.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4108 PF13390.6 EAX67712.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX67713.1 - 5.9e-07 29.2 0.1 1.6e-06 27.7 0.0 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX67714.1 - 3.9e-57 193.5 3.8 4.4e-57 193.3 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_4 PF13637.6 EAX67715.1 - 1.8e-30 104.9 5.3 2e-08 34.6 0.3 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX67715.1 - 2.2e-30 105.0 0.7 1.2e-10 41.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX67715.1 - 1.9e-27 95.0 0.1 1.4e-06 28.4 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX67715.1 - 5.5e-24 81.6 0.2 4.9e-05 23.4 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAX67715.1 - 3.2e-19 68.4 1.8 0.00022 21.6 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EAX67715.1 - 0.0015 18.5 0.9 1.2 9.2 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX67715.1 - 0.047 14.0 0.1 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase PapD_N PF00345.20 EAX67716.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX67716.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4107 PF13389.6 EAX67717.1 - 2e-43 148.3 1.0 2.2e-43 148.2 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67717.1 - 0.12 12.8 0.6 0.15 12.4 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PadR PF03551.14 EAX67720.1 - 0.076 13.0 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Phage_fiber PF03335.13 EAX67721.1 - 6.1 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX67722.1 - 0.025 15.0 1.1 0.036 14.5 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67722.1 - 0.18 11.9 3.0 5.8 7.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein P22_AR_C PF10548.9 EAX67724.1 - 0.057 13.6 0.1 16 5.8 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain Ank_2 PF12796.7 EAX67725.1 - 1.2e-91 301.4 4.6 1.6e-17 63.8 0.0 4.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX67725.1 - 8.9e-60 198.3 0.0 1.2e-12 48.1 0.0 6.6 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX67725.1 - 4.9e-46 154.2 0.0 3.7e-08 33.5 0.0 8.8 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX67725.1 - 1.4e-38 129.7 0.0 3.4e-05 24.1 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX67725.1 - 2.4e-37 122.7 0.0 0.0083 16.6 0.0 9.4 8 1 1 9 9 9 9 Ankyrin repeat YfmQ PF10787.9 EAX67725.1 - 3.3e-07 30.2 0.5 0.14 12.0 0.0 4.8 1 1 4 5 5 5 2 Uncharacterised protein from bacillus cereus group CdAMP_rec PF06153.11 EAX67725.1 - 1.9e-05 24.8 2.2 14 5.9 0.0 5.1 1 1 4 5 5 5 0 Cyclic-di-AMP receptor DUF5049 PF16468.5 EAX67725.1 - 0.0001 22.1 2.6 2.4 8.1 0.0 6.2 7 1 1 8 8 8 1 Domain of unknown function (DUF5049) Pox_E8 PF03394.13 EAX67725.1 - 0.00038 20.1 0.1 1.8 8.0 0.0 4.3 1 1 4 5 5 5 1 Poxvirus E8 protein HTH_22 PF13309.6 EAX67725.1 - 0.0038 17.3 3.2 6.9 6.8 0.1 5.8 7 2 2 9 9 8 1 HTH domain L_protein_N PF15518.6 EAX67725.1 - 0.0093 15.8 0.1 3.3 7.6 0.0 3.8 3 1 1 4 4 4 1 L protein N-terminus DUF249 PF03158.13 EAX67725.1 - 0.015 15.0 0.3 8.8 6.0 0.0 2.9 3 1 0 3 3 3 0 Multigene family 530 protein Pox_F17 PF04767.12 EAX67725.1 - 0.023 15.2 0.1 65 4.1 0.0 4.5 2 1 3 5 5 5 0 DNA-binding 11 kDa phosphoprotein DUF4107 PF13389.6 EAX67726.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67726.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX67728.1 - 4e-10 39.6 19.5 6.5e-09 35.7 5.2 3.6 4 0 0 4 4 4 2 Phage tail repeat like ComC PF03047.14 EAX67728.1 - 0.68 9.8 3.5 0.97 9.3 1.4 2.4 2 0 0 2 2 2 0 COMC family DUF4107 PF13389.6 EAX67730.1 - 8.2e-54 182.1 0.7 1.1e-53 181.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX67731.1 - 6.7e-109 363.0 7.3 7.7e-109 362.8 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MGC-24 PF05283.11 EAX67734.1 - 4.8 7.6 6.0 5.8 7.4 6.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX67735.1 - 0.091 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67735.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1031 PF06275.11 EAX67736.1 - 0.054 13.7 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX67736.1 - 0.081 13.0 0.3 0.45 10.6 0.3 2.2 1 1 1 2 2 2 0 Annexin GPS2_interact PF15784.5 EAX67737.1 - 0.045 14.2 1.3 0.062 13.8 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67737.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain T5orf172 PF10544.9 EAX67738.1 - 8.5e-05 23.0 0.2 0.00022 21.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX67738.1 - 0.0068 16.3 0.1 0.026 14.3 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Baculo_ME53 PF06061.11 EAX67738.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX67738.1 - 0.04 13.5 1.4 0.37 10.3 0.5 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX67739.1 - 3.2e-27 95.5 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX67739.1 - 0.18 12.2 0.9 0.76 10.3 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB APC_u14 PF16635.5 EAX67739.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr PSP PF04046.16 EAX67740.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67741.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX67742.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX67742.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX67742.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX67742.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX67743.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX67744.1 - 0.027 14.5 0.3 0.027 14.5 0.3 3.1 4 0 0 4 4 4 0 Phage tail repeat like Prp18 PF02840.15 EAX67745.1 - 0.0068 16.5 0.0 0.0079 16.2 0.0 1.1 1 0 0 1 1 1 1 Prp18 domain DDE_Tnp_4 PF13359.6 EAX67747.1 - 1.4e-30 106.0 0.0 2.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX67747.1 - 9e-08 32.0 0.1 3.2e-07 30.2 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain Pox_A32 PF04665.12 EAX67749.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein 2_5_RNA_ligase2 PF13563.6 EAX67750.1 - 0.075 12.9 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Col_cuticle_N PF01484.17 EAX67750.1 - 0.21 11.7 0.1 0.54 10.4 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Spo12 PF05032.12 EAX67753.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Mito_fiss_reg PF05308.11 EAX67754.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX67754.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HNH_3 PF13392.6 EAX67755.1 - 4e-08 32.9 0.2 6.5e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF4107 PF13389.6 EAX67756.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67756.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_D5 PF03288.16 EAX67757.1 - 9.5e-05 22.8 2.0 0.00058 20.3 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DNA_pol_B_2 PF03175.13 EAX67758.1 - 1.1e-21 77.3 7.3 1.3e-21 77.0 7.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67758.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Isy1 PF06246.12 EAX67758.1 - 0.097 12.2 0.8 0.2 11.2 0.7 1.6 1 1 0 1 1 1 0 Isy1-like splicing family HD_3 PF13023.6 EAX67759.1 - 0.057 13.3 0.4 0.082 12.8 0.4 1.2 1 0 0 1 1 1 0 HD domain PTR PF12789.7 EAX67760.1 - 1.7e-27 95.3 11.6 1.7e-27 95.3 11.6 3.7 3 1 0 3 3 3 1 Phage tail repeat like Phage_fiber PF03335.13 EAX67760.1 - 5.6 7.4 15.9 3.9 7.9 1.1 3.6 4 0 0 4 4 4 0 Phage tail fibre repeat KilA-N PF04383.13 EAX67762.1 - 2.9e-32 110.8 1.0 4.8e-32 110.1 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Pox_D5 PF03288.16 EAX67763.1 - 4.6e-06 27.0 2.9 2.5e-05 24.7 2.9 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67763.1 - 0.019 15.6 0.1 0.036 14.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67763.1 - 0.053 13.5 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX67764.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX67765.1 - 0.12 12.2 4.1 0.15 12.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OAD_gamma PF04277.13 EAX67765.1 - 8.8 7.0 6.3 9.1 7.0 6.3 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EpuA PF11772.8 EAX67766.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DNA_pol_B_2 PF03175.13 EAX67767.1 - 6.9e-19 68.1 8.7 1.3e-18 67.2 8.7 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PSP PF04046.16 EAX67768.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67769.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PapD_N PF00345.20 EAX67770.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX67770.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX67770.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Apolipoprotein PF01442.18 EAX67772.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1493 PF07377.12 EAX67774.1 - 0.028 14.9 0.8 0.056 13.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF257 PF03192.13 EAX67775.1 - 0.0011 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX67775.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX67777.1 - 6.8e-06 25.7 0.6 7.7e-06 25.5 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX67777.1 - 0.041 14.2 0.5 0.041 14.2 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Annexin PF00191.20 EAX67778.1 - 0.055 13.5 0.3 0.17 12.0 0.2 1.9 1 1 1 2 2 2 0 Annexin DUF1031 PF06275.11 EAX67778.1 - 0.096 13.0 0.1 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) DUF2791 PF10923.8 EAX67778.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF4106 PF13388.6 EAX67781.1 - 5.9e-10 39.0 33.7 5.9e-06 25.8 7.3 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) UPF0242 PF06785.11 EAX67781.1 - 2 8.5 10.8 2.2 8.3 10.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HD_2 PF12917.7 EAX67782.1 - 0.099 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Spore_coat_CotO PF14153.6 EAX67783.1 - 0.007 16.3 5.6 0.0097 15.9 5.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO FAS_N PF17828.1 EAX67783.1 - 0.0074 16.3 0.2 0.01 15.8 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX67785.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX67787.1 - 0.036 14.1 1.2 0.036 14.1 1.2 3.4 4 1 0 4 4 4 0 Phage tail repeat like DUF4795 PF16043.5 EAX67787.1 - 1.5 8.4 6.2 14 5.2 6.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX67787.1 - 3.2 8.2 9.1 3.1 8.2 0.3 3.5 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX67787.1 - 4.7 7.8 7.3 24 5.6 0.3 3.3 3 1 0 3 3 3 0 YmaF family DNA_pol_B_2 PF03175.13 EAX67789.1 - 8.8e-11 41.3 8.3 1.1e-10 41.0 4.4 2.0 1 1 1 2 2 2 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX67789.1 - 0.1 12.1 0.8 0.2 11.2 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX67789.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF4116 PF13475.6 EAX67790.1 - 0.0065 16.2 0.2 0.023 14.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX67791.1 - 0.017 15.6 1.3 0.027 14.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) MG2 PF01835.19 EAX67793.1 - 1e-06 29.1 1.1 0.0064 16.9 0.1 3.4 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX67793.1 - 1.9e-05 24.9 3.4 0.026 14.8 0.1 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX67793.1 - 0.0085 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain NPCBM_assoc PF10633.9 EAX67793.1 - 0.0098 16.1 5.1 0.082 13.2 0.1 4.0 3 2 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase bMG6 PF17962.1 EAX67793.1 - 0.026 14.7 0.6 3.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 He_PIG PF05345.12 EAX67793.1 - 0.026 14.7 2.0 0.29 11.4 0.1 3.3 3 0 0 3 3 3 0 Putative Ig domain DUF2914 PF11141.8 EAX67793.1 - 0.031 14.0 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Peptidase_M60_C PF18630.1 EAX67793.1 - 0.055 13.6 0.7 1.9 8.6 0.1 3.3 3 0 0 3 3 3 0 Peptidase M60 C-terminal domain PKD PF00801.20 EAX67793.1 - 0.073 12.9 0.1 0.73 9.7 0.0 2.8 2 0 0 2 2 2 0 PKD domain AAA_22 PF13401.6 EAX67794.1 - 5.5e-05 23.5 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67794.1 - 6.5e-05 23.0 2.6 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67794.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67794.1 - 0.00077 19.3 0.8 0.0022 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67794.1 - 0.0027 17.5 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67794.1 - 0.0075 16.6 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67794.1 - 0.052 13.0 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67794.1 - 0.091 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67794.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67794.1 - 0.19 12.0 4.1 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX67794.1 - 0.77 10.2 4.2 0.38 11.2 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1727 PF08353.10 EAX67795.1 - 0.088 12.7 0.4 0.12 12.4 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1727) PTR PF12789.7 EAX67797.1 - 3e-16 59.2 1.9 3e-16 59.2 1.9 3.4 5 0 0 5 5 5 1 Phage tail repeat like JMY PF15871.5 EAX67798.1 - 0.0048 16.3 0.4 0.0065 15.8 0.4 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX67798.1 - 0.14 12.2 0.9 0.31 11.1 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX67798.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain Clathrin PF00637.20 EAX67799.1 - 3.7e-57 192.2 8.5 1.4e-29 102.8 1.9 2.1 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_7 PF13176.6 EAX67799.1 - 0.12 12.4 0.2 6.7 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_A32 PF04665.12 EAX67800.1 - 1.1e-07 31.6 1.4 1.3e-07 31.3 1.4 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67800.1 - 0.0047 16.6 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67800.1 - 0.042 13.6 0.1 0.084 12.6 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX67801.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67801.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67801.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67801.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PSP PF04046.16 EAX67803.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP AAA_22 PF13401.6 EAX67804.1 - 6.4e-05 23.3 0.1 0.00034 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67804.1 - 7.3e-05 22.8 2.7 0.00013 22.0 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67804.1 - 0.00041 20.2 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67804.1 - 0.001 19.0 1.0 0.0035 17.2 1.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX67804.1 - 0.0075 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67804.1 - 0.026 14.3 0.4 0.87 9.3 0.0 2.5 1 1 2 3 3 3 0 IstB-like ATP binding protein PhoH PF02562.16 EAX67804.1 - 0.041 13.3 0.1 0.061 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX67804.1 - 0.078 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX67804.1 - 0.11 12.9 0.1 0.37 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67804.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX67805.1 - 2e-05 24.9 0.2 0.00014 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67805.1 - 4.3e-05 23.3 0.3 0.27 10.9 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX67805.1 - 5.5e-05 22.8 2.4 5.5e-05 22.8 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX67805.1 - 0.00012 22.2 3.2 0.00024 21.2 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67805.1 - 0.00041 20.2 0.1 0.00074 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67805.1 - 0.00092 19.1 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67805.1 - 0.0014 18.3 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67805.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67805.1 - 0.049 13.2 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX67805.1 - 0.051 13.1 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX67805.1 - 0.058 13.8 0.1 0.53 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX67805.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67805.1 - 0.23 11.7 4.3 6.4 7.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3783 PF12646.7 EAX67805.1 - 0.25 11.3 2.2 1.5 8.8 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) FAR1 PF03101.15 EAX67806.1 - 0.011 16.4 0.1 0.021 15.5 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Pox_A32 PF04665.12 EAX67807.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67807.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67807.1 - 4.1e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67807.1 - 0.00014 21.9 3.4 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67807.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67807.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67807.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67807.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX67807.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX67807.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67807.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX67807.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MGC-24 PF05283.11 EAX67808.1 - 0.66 10.4 5.2 1.4 9.4 5.2 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PadR PF03551.14 EAX67809.1 - 0.096 12.7 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family CBM_15 PF03426.14 EAX67809.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) PTR PF12789.7 EAX67810.1 - 3.6e-30 103.8 31.3 9.4e-30 102.5 16.4 2.9 3 1 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX67810.1 - 0.0039 17.7 12.2 1.5 9.5 4.8 3.4 3 0 0 3 3 3 2 YmaF family PH_TFIIH PF08567.11 EAX67810.1 - 0.1 12.9 2.1 2 8.8 0.2 2.6 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain Pox_A32 PF04665.12 EAX67811.1 - 5.4e-05 22.8 2.9 8.8e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67811.1 - 0.0023 18.0 1.0 0.0053 16.8 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX67811.1 - 0.011 15.4 0.3 0.024 14.2 0.3 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX67811.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX67811.1 - 0.081 13.2 2.0 0.17 12.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DNA_pol_B_2 PF03175.13 EAX67812.1 - 5.8e-17 61.7 2.1 6.4e-17 61.6 2.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67812.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) MULE PF10551.9 EAX67813.1 - 9.7e-11 42.0 0.8 1.4e-10 41.4 0.2 1.6 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX67813.1 - 0.0049 16.6 0.1 0.019 14.7 0.1 1.8 1 1 0 1 1 1 1 Transposase Transposase_mut PF00872.18 EAX67813.1 - 0.0068 15.3 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF1493 PF07377.12 EAX67814.1 - 0.051 14.0 1.6 0.054 14.0 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67814.1 - 0.41 10.7 3.7 6.6 6.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_D5 PF03288.16 EAX67815.1 - 4.9e-05 23.7 2.1 0.00022 21.7 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX67815.1 - 0.012 14.7 1.0 0.018 14.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Pox_A32 PF04665.12 EAX67816.1 - 5e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX67816.1 - 0.0047 16.9 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX67816.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX67816.1 - 0.086 13.1 1.7 0.2 11.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX67817.1 - 1.1e-116 388.5 8.5 1.4e-116 388.2 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX67817.1 - 0.12 12.7 0.9 0.26 11.6 0.9 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3839 PF12943.7 EAX67818.1 - 9.9e-80 267.5 9.0 1.3e-79 267.1 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX67820.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain ACP_PD PF04336.12 EAX67821.1 - 0.13 12.7 1.0 0.56 10.7 0.0 2.3 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase T5orf172 PF10544.9 EAX67822.1 - 1.4e-06 28.8 0.2 3.1e-06 27.7 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX67823.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX67825.1 - 0.067 13.1 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP DUF4378 PF14309.6 EAX67827.1 - 0.036 14.5 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) La PF05383.17 EAX67827.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 La domain DNA_pol_B_2 PF03175.13 EAX67828.1 - 2.4e-22 79.5 9.0 6.8e-22 78.0 9.0 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX67828.1 - 0.075 13.0 0.0 0.83 9.7 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor ARA70 PF12489.8 EAX67829.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DNA_pol_B_2 PF03175.13 EAX67831.1 - 3e-20 72.5 3.7 3e-20 72.5 3.7 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67831.1 - 0.062 12.6 0.1 0.09 12.1 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX67831.1 - 0.19 11.8 1.1 17 5.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) T5orf172 PF10544.9 EAX67833.1 - 6.6e-07 29.8 0.1 1.2e-06 28.9 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain Glyco_hydro_30 PF02055.16 EAX67834.1 - 2e-30 106.0 0.1 2.5e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX67834.1 - 5.9e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAX67834.1 - 0.0016 18.1 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 TMP PF05017.14 EAX67836.1 - 0.044 14.3 4.0 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67837.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX67840.1 - 4.2e-07 29.7 3.9 6.1e-07 29.1 3.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67840.1 - 0.0049 16.5 0.2 0.0061 16.2 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67840.1 - 0.055 13.2 0.2 0.27 11.0 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX67840.1 - 0.061 12.8 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF3783 PF12646.7 EAX67840.1 - 0.2 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67840.1 - 0.36 11.0 8.1 5.4 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX67841.1 - 6.3e-08 32.4 0.9 7.7e-08 32.1 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67841.1 - 0.0037 16.9 0.1 0.0039 16.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX67841.1 - 0.051 13.3 0.1 0.089 12.5 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67841.1 - 0.09 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX67841.1 - 0.1 13.0 0.6 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) KilA-N PF04383.13 EAX67842.1 - 6.6e-19 67.8 0.1 8.4e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX67842.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4107 PF13389.6 EAX67844.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX67845.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF1493 PF07377.12 EAX67846.1 - 0.076 13.5 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ResIII PF04851.15 EAX67849.1 - 6.5e-05 23.0 2.6 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX67849.1 - 7.2e-05 23.1 0.1 0.00039 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX67849.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67849.1 - 0.00072 19.4 0.7 0.0022 17.9 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67849.1 - 0.004 16.9 0.2 0.27 11.0 0.0 2.6 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67849.1 - 0.0061 16.9 0.0 0.009 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67849.1 - 0.052 13.0 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67849.1 - 0.084 13.3 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67849.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX67849.1 - 0.15 12.3 3.8 5.5 7.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX67849.1 - 0.85 10.1 4.2 0.38 11.2 1.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Gly-zipper_Omp PF13488.6 EAX67851.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX67851.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX67851.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif FAR1 PF03101.15 EAX67853.1 - 0.037 14.7 0.2 0.1 13.3 0.2 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain PSP PF04046.16 EAX67854.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MULE PF10551.9 EAX67855.1 - 1.3e-10 41.6 1.0 2.1e-10 40.9 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX67855.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DUF1493 PF07377.12 EAX67858.1 - 0.0094 16.4 0.5 0.018 15.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX67859.1 - 0.011 15.4 0.4 0.044 13.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AbiJ_NTD4 PF18863.1 EAX67860.1 - 0.025 15.0 0.3 0.047 14.1 0.3 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX67860.1 - 0.028 14.5 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 VirK protein DUF2939 PF11159.8 EAX67861.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX67861.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX67862.1 - 0.0094 16.0 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF1493 PF07377.12 EAX67863.1 - 0.039 14.4 1.0 0.061 13.8 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX67863.1 - 0.85 9.7 5.3 6 7.0 0.2 2.6 2 1 1 3 3 3 0 Uncharacterized Strongylid L4 protein GPS2_interact PF15784.5 EAX67864.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX67864.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Mitofilin PF09731.9 EAX67867.1 - 0.017 14.0 2.0 0.023 13.6 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Noggin PF05806.12 EAX67867.1 - 0.031 14.2 1.1 0.046 13.6 1.1 1.1 1 0 0 1 1 1 0 Noggin DUF3408 PF11888.8 EAX67867.1 - 6.5 6.9 10.5 19 5.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3408) MULE PF10551.9 EAX67868.1 - 0.0039 17.6 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Annexin PF00191.20 EAX67870.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Annexin FAS_N PF17828.1 EAX67872.1 - 0.0012 18.8 0.4 0.0018 18.3 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX67873.1 - 3.7e-98 327.8 6.3 4.2e-98 327.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX67873.1 - 0.0066 16.1 0.8 0.013 15.2 0.8 1.6 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX67873.1 - 0.11 12.8 1.9 0.23 11.8 1.8 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3839 PF12943.7 EAX67875.1 - 5.6e-157 520.4 13.9 6.7e-157 520.2 13.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67875.1 - 0.1 12.4 1.0 0.41 10.5 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX67875.1 - 0.11 12.9 0.5 0.95 9.9 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX67875.1 - 1.1 9.7 7.5 1.9 9.0 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX67877.1 - 0.12 12.9 1.7 0.15 12.5 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_D5 PF03288.16 EAX67879.1 - 3.5e-05 24.2 2.1 0.0002 21.8 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67879.1 - 0.021 15.4 0.1 0.043 14.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX67879.1 - 0.059 13.4 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain TMP PF05017.14 EAX67882.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX67884.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AAA_22 PF13401.6 EAX67887.1 - 5.6e-05 23.4 0.1 0.00033 21.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67887.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67887.1 - 0.00047 20.0 0.0 0.00076 19.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67887.1 - 0.0013 18.6 1.1 0.0042 16.9 1.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67887.1 - 0.0037 17.0 0.4 0.31 10.7 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX67887.1 - 0.0083 16.5 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX67887.1 - 0.053 13.0 0.1 0.081 12.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX67887.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX67887.1 - 0.1 12.8 4.7 1.9 8.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA PF00004.29 EAX67887.1 - 0.13 12.7 0.1 0.78 10.2 0.0 2.0 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX67887.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2897 PF11446.8 EAX67888.1 - 0.18 11.7 3.0 0.35 10.8 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX67889.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX67890.1 - 6.3e-80 268.1 9.7 7.8e-80 267.8 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX67890.1 - 0.018 15.6 0.5 0.035 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX67890.1 - 0.036 14.5 0.4 0.043 14.3 0.4 1.1 1 0 0 1 1 1 0 Fez1 PTR PF12789.7 EAX67891.1 - 1.2e-16 60.5 1.9 1.2e-16 60.5 1.9 4.8 5 1 1 6 6 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX67891.1 - 0.0056 16.3 0.3 0.0056 16.3 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX67892.1 - 8.2e-09 35.3 0.1 1.2e-08 34.7 0.1 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67892.1 - 0.00026 20.7 0.0 0.00034 20.3 0.0 1.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX67892.1 - 0.071 13.0 1.6 0.1 12.4 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4107 PF13389.6 EAX67893.1 - 0.095 12.9 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX67894.1 - 4.2e-158 527.0 21.8 6.2e-158 526.4 21.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX67894.1 - 0.0053 17.0 0.1 0.39 11.0 0.2 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX67894.1 - 0.094 13.3 0.7 0.23 12.1 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX67894.1 - 0.27 11.7 6.6 3.5 8.1 0.3 3.2 3 0 0 3 3 3 0 WYL domain KilA-N PF04383.13 EAX67897.1 - 6e-23 80.8 0.3 1e-22 80.1 0.3 1.3 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX67897.1 - 0.044 13.7 0.9 0.13 12.2 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMP PF05017.14 EAX67898.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX67899.1 - 3.1e-07 30.1 0.2 6.3e-07 29.1 0.1 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX67901.1 - 7.1e-24 84.5 7.1 4e-23 82.0 7.0 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX67901.1 - 0.066 13.2 0.0 0.84 9.7 0.0 2.7 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX67901.1 - 0.1 12.8 0.0 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX67901.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 TMP PF05017.14 EAX67902.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67903.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP MULE PF10551.9 EAX67905.1 - 8.4e-11 42.1 1.1 2e-10 40.9 0.2 2.0 2 0 0 2 2 2 1 MULE transposase domain PSP PF04046.16 EAX67908.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX67909.1 - 1.1e-148 493.3 17.5 1.4e-148 493.0 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX67909.1 - 0.13 12.7 0.3 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX67909.1 - 1.2 9.7 8.8 3.1 8.3 1.4 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX67909.1 - 1.2 9.5 3.9 0.87 9.9 0.5 2.5 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit PTR PF12789.7 EAX67911.1 - 1.4e-36 124.3 24.4 1.2e-32 111.7 13.8 3.8 4 1 1 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX67912.1 - 0.15 12.6 1.6 1.2 9.7 1.6 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX67912.1 - 1.1 9.6 7.6 1.6 9.1 0.3 2.8 3 0 0 3 3 3 0 Phage tail fibre repeat TMP PF05017.14 EAX67914.1 - 0.036 14.6 2.6 11 7.2 0.2 2.7 2 0 0 2 2 2 0 TMP repeat DUF1493 PF07377.12 EAX67915.1 - 0.071 13.6 0.6 0.15 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX67916.1 - 1.2e-11 44.4 17.4 6.5e-09 35.7 5.2 4.6 4 1 0 4 4 4 3 Phage tail repeat like Myb_DNA-binding PF00249.31 EAX67917.1 - 1.2e-31 108.6 0.5 1.8e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX67917.1 - 1.6e-22 79.5 2.1 1.4e-15 57.3 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX67917.1 - 2.5e-07 30.7 6.1 0.00051 20.0 0.1 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX67917.1 - 8.8e-05 22.3 5.9 0.0019 18.1 0.5 2.8 1 1 1 2 2 2 2 Myb DNA-binding like DUF4424 PF14415.6 EAX67917.1 - 0.00048 19.5 0.4 0.00049 19.5 0.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4424) SANT_DAMP1_like PF16282.5 EAX67917.1 - 0.0024 18.0 1.1 0.065 13.4 0.1 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX67917.1 - 0.003 17.7 0.8 1.6 9.0 0.3 3.0 1 1 1 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 EAX67917.1 - 0.0042 17.2 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF489 PF04356.12 EAX67917.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) RTP801_C PF07809.11 EAX67917.1 - 0.1 12.5 0.5 12 5.8 0.1 2.3 2 0 0 2 2 2 0 RTP801 C-terminal region ArsC PF03960.15 EAX67918.1 - 0.054 13.5 0.7 0.085 12.9 0.6 1.4 1 1 0 1 1 1 0 ArsC family Pox_D5 PF03288.16 EAX67919.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Trypan_PARP PF05887.11 EAX67920.1 - 0.036 14.1 8.3 0.056 13.4 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX67920.1 - 2.5 8.5 5.3 3.6 8.0 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX67921.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX67922.1 - 1.3e-32 111.9 0.3 3.5e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67922.1 - 0.0049 17.5 0.1 0.013 16.1 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DUF4106 PF13388.6 EAX67926.1 - 1.4e-206 686.7 14.7 1.6e-206 686.5 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX67926.1 - 0.019 14.8 0.2 0.037 13.9 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX67926.1 - 0.12 12.4 14.5 0.14 12.1 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF737 PF05300.11 EAX67926.1 - 4.6 7.5 12.1 2.5 8.4 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF3839 PF12943.7 EAX67928.1 - 3.5e-133 442.5 8.9 4e-133 442.3 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX67928.1 - 0.028 14.6 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DNA_pol_B_2 PF03175.13 EAX67929.1 - 1.7e-17 63.5 2.4 2e-17 63.2 2.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Imm70 PF15601.6 EAX67931.1 - 0.19 11.3 5.7 7.6 6.1 0.2 3.3 1 1 3 4 4 4 0 Immunity protein 70 DUF4107 PF13389.6 EAX67932.1 - 1.6e-51 174.7 0.8 2.1e-51 174.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX67932.1 - 0.12 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Arm-DNA-bind_5 PF17293.2 EAX67934.1 - 0.0081 16.6 1.0 0.0081 16.6 1.0 2.5 2 1 0 2 2 2 1 Arm DNA-binding domain DUF4107 PF13389.6 EAX67935.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF4841 PF16129.5 EAX67936.1 - 0.063 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DUF4108 PF13390.6 EAX67937.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_4 PF13637.6 EAX67938.1 - 4.4e-25 87.7 0.4 7.1e-13 48.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX67938.1 - 2.6e-22 78.2 1.5 1e-08 35.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX67938.1 - 4.7e-21 74.6 3.9 3.3e-10 40.0 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX67938.1 - 4e-18 63.6 1.0 3.9e-06 26.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX67938.1 - 7.6e-18 64.9 0.8 7.8e-15 55.2 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Arg_repressor PF01316.21 EAX67938.1 - 0.0027 17.4 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 1 Arginine repressor, DNA binding domain RRM_2 PF04059.12 EAX67938.1 - 0.031 14.5 0.0 4.7 7.5 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif 2 Mic1 PF07035.12 EAX67938.1 - 0.074 12.8 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Colon cancer-associated protein Mic1-like YfmQ PF10787.9 EAX67938.1 - 0.12 12.1 0.0 41 3.9 0.0 2.8 1 1 2 3 3 3 0 Uncharacterised protein from bacillus cereus group PTR PF12789.7 EAX67939.1 - 2.1e-53 178.2 34.1 3.9e-33 113.3 13.6 3.0 3 1 1 4 4 4 2 Phage tail repeat like BRO1 PF03097.18 EAX67939.1 - 0.027 13.3 0.2 0.065 12.0 0.0 1.6 2 0 0 2 2 2 0 BRO1-like domain PH_TFIIH PF08567.11 EAX67939.1 - 6.3 7.2 6.8 65 4.0 0.1 3.9 2 1 3 5 5 5 0 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 EAX67941.1 - 0.025 14.4 0.9 0.031 14.2 0.9 1.0 1 0 0 1 1 1 0 PIN like domain FliD_N PF02465.18 EAX67941.1 - 0.15 12.8 4.0 0.2 12.4 4.0 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus GET2 PF08690.10 EAX67941.1 - 0.85 9.2 7.7 0.89 9.2 7.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PaRep2a PF07903.11 EAX67943.1 - 0.092 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX67943.1 - 0.47 10.4 8.0 0.16 11.9 2.9 2.3 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX67944.1 - 1.2e-22 80.5 5.1 1.6e-22 80.0 5.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX67945.1 - 1.3e-05 24.7 2.9 1.5e-05 24.6 1.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX67945.1 - 3e-05 24.3 0.2 0.00022 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX67945.1 - 0.00013 21.8 0.4 0.38 10.5 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX67945.1 - 0.0003 20.8 4.6 0.00048 20.2 3.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67945.1 - 0.00051 19.8 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67945.1 - 0.0016 18.3 0.7 0.004 17.0 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67945.1 - 0.0018 18.0 0.4 0.014 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67945.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67945.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX67945.1 - 0.077 13.4 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX67945.1 - 0.077 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX67945.1 - 0.084 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX67945.1 - 0.8 10.0 3.8 24 5.2 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) IFT20 PF14931.6 EAX67945.1 - 1.4 9.1 11.3 0.94 9.7 0.9 3.6 3 1 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Pox_D5 PF03288.16 EAX67946.1 - 6e-05 23.4 2.2 0.00033 21.1 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67946.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX67947.1 - 3.5e-09 36.0 0.1 7.8e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX67947.1 - 0.022 14.1 0.6 0.031 13.6 0.6 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX67947.1 - 0.13 12.4 1.1 0.28 11.2 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) MAJIN PF15077.6 EAX67949.1 - 2.8 7.7 9.9 2.8 7.7 9.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein FAS_N PF17828.1 EAX67950.1 - 0.1 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX67951.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myc_N PF01056.18 EAX67952.1 - 0.036 14.0 2.8 0.032 14.1 2.8 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF688 PF05097.12 EAX67952.1 - 0.12 11.6 1.2 0.12 11.5 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) EP400_N PF15790.5 EAX67952.1 - 0.13 11.1 1.2 0.14 10.9 1.2 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal NOA36 PF06524.12 EAX67952.1 - 0.75 9.1 5.9 0.83 8.9 5.9 1.0 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EAX67952.1 - 2.9 5.9 8.3 3.1 5.8 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.19 EAX67952.1 - 6.4 7.4 14.7 8.1 7.1 14.7 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAC1 PF16094.5 EAX67952.1 - 10 5.2 6.9 10 5.2 6.9 1.0 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DUF3839 PF12943.7 EAX67953.1 - 7.4e-56 189.3 1.7 8.3e-56 189.1 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX67954.1 - 3.5e-09 36.5 0.6 6.6e-09 35.6 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX67956.1 - 2.3e-07 30.5 0.1 2.6e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX67958.1 - 4e-158 524.1 14.3 5.2e-158 523.8 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67958.1 - 0.15 11.9 1.3 0.56 10.1 0.4 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX67958.1 - 0.16 12.4 6.3 0.71 10.4 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX67961.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX67963.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX67964.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX67965.1 - 3.6e-155 514.5 14.2 4.1e-155 514.3 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX67965.1 - 0.068 13.5 0.6 6.3 7.1 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX67965.1 - 0.16 11.8 1.5 0.84 9.5 1.5 2.1 1 1 0 1 1 1 0 Nucleotidyltransferase DUF5398 PF17376.2 EAX67965.1 - 0.2 12.3 2.8 0.89 10.2 0.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX67965.1 - 5.1 7.6 7.9 1.6 9.3 0.5 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX67966.1 - 2.9e-27 95.7 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX67966.1 - 0.16 12.4 0.9 0.85 10.1 0.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB APC_u14 PF16635.5 EAX67966.1 - 0.2 12.2 2.2 0.28 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Pox_A32 PF04665.12 EAX67967.1 - 3.6e-07 29.9 3.2 4.7e-07 29.5 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67967.1 - 0.0041 16.8 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67967.1 - 0.052 13.1 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67967.1 - 0.058 13.1 0.2 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX67967.1 - 0.093 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX67967.1 - 0.18 11.8 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67967.1 - 0.4 10.9 8.6 5.4 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX67968.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX67969.1 - 3.4e-07 30.0 0.1 3.9e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Ly49 PF08391.10 EAX67972.1 - 0.36 11.2 2.5 0.73 10.2 2.5 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pox_A32 PF04665.12 EAX67973.1 - 8.5e-07 28.7 1.8 8.5e-07 28.7 1.8 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX67973.1 - 3.2e-05 23.7 0.2 0.31 10.7 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX67973.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX67973.1 - 0.00032 20.8 4.2 0.00065 19.7 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX67973.1 - 0.00064 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX67973.1 - 0.0027 17.5 1.3 0.0064 16.3 0.7 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX67973.1 - 0.004 16.8 2.2 0.015 14.9 0.1 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX67973.1 - 0.014 15.8 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX67973.1 - 0.078 12.5 0.0 0.26 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX67973.1 - 0.081 13.0 0.7 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX67973.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX67973.1 - 0.12 12.8 0.1 0.91 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX67973.1 - 0.62 10.8 11.4 0.33 11.7 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF4107 PF13389.6 EAX67974.1 - 7.4e-71 237.5 2.2 9.7e-71 237.2 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX67976.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX67977.1 - 1.3e-21 77.0 5.6 1.1e-20 74.0 5.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67977.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF2939 PF11159.8 EAX67978.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX67978.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX67978.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX67978.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX67979.1 - 0.076 13.0 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX67981.1 - 5.4e-138 458.3 12.5 1.6e-137 456.7 12.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67981.1 - 0.6 10.6 3.8 3 8.4 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX67982.1 - 1.3e-29 103.4 7.5 1.7e-29 103.1 7.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX67982.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PSP PF04046.16 EAX67983.1 - 0.05 13.5 0.6 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX67984.1 - 2.8e-121 403.5 13.4 3.5e-121 403.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67984.1 - 0.026 14.9 2.5 1.8 9.0 0.0 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX67984.1 - 0.098 12.2 0.6 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX67984.1 - 0.22 11.4 1.9 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DNA_pol_B_2 PF03175.13 EAX67985.1 - 2.8e-23 82.5 3.9 4e-23 82.0 3.9 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Amidase02_C PF12123.8 EAX67987.1 - 0.0035 17.0 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX67988.1 - 9.1e-148 490.2 12.0 1e-147 490.1 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX67988.1 - 6.6 7.3 6.7 1.6 9.3 0.5 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RFX_DNA_binding PF02257.15 EAX67989.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX67989.1 - 0.00035 21.0 1.5 0.00067 20.1 1.5 1.5 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX67989.1 - 0.043 13.8 0.8 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX67990.1 - 5e-42 142.3 0.5 1.1e-41 141.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX67990.1 - 0.052 14.2 0.1 0.15 12.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX67991.1 - 2.6e-156 518.2 12.2 3.3e-156 517.9 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX67991.1 - 0.021 15.3 2.1 0.088 13.3 0.5 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX67991.1 - 0.37 11.1 5.0 12 6.3 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal KELK PF15796.5 EAX67991.1 - 0.38 11.2 6.3 2 8.9 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX67992.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX67992.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX67993.1 - 1.2e-144 480.0 9.7 1.4e-144 479.8 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX67993.1 - 0.099 12.5 0.3 0.19 11.6 0.3 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase Trypan_PARP PF05887.11 EAX67996.1 - 0.079 12.9 9.6 0.12 12.3 9.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX67996.1 - 3.7 8.0 6.2 5.2 7.5 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX67997.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX67997.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX67997.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX67997.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX67997.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX67997.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_D5 PF03288.16 EAX67999.1 - 3.8e-05 24.1 2.7 0.0003 21.2 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX67999.1 - 0.048 14.3 0.2 0.093 13.4 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX68000.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX68003.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX68004.1 - 0.024 15.1 0.8 0.033 14.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68004.1 - 1.3 9.0 5.1 1.4 8.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68005.1 - 0.0049 16.9 0.2 0.0066 16.4 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX68006.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DHC PF09626.10 EAX68007.1 - 4.4 8.2 5.8 57 4.6 1.8 3.0 1 1 1 3 3 3 0 Dihaem cytochrome c DUF3839 PF12943.7 EAX68008.1 - 1.1e-152 506.4 14.3 1.3e-152 506.1 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68008.1 - 1.2 9.7 8.2 2.3 8.8 1.4 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX68009.1 - 2.1e-67 226.3 9.7 7.3e-67 224.6 9.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68009.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX68010.1 - 5.5e-17 61.8 2.6 6.2e-17 61.6 2.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX68011.1 - 2.9e-40 136.6 0.3 7.3e-40 135.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX68011.1 - 0.043 14.4 0.3 0.13 12.9 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX68012.1 - 8.1e-05 22.2 4.1 0.00013 21.6 4.1 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX68012.1 - 0.0036 17.3 0.8 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX68012.1 - 0.058 13.7 1.4 0.15 12.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX68012.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MG2 PF01835.19 EAX68014.1 - 5.8e-06 26.7 0.7 0.0046 17.4 0.1 3.3 3 1 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX68014.1 - 7.5e-05 23.0 1.4 0.019 15.2 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX68014.1 - 0.0058 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain NPCBM_assoc PF10633.9 EAX68014.1 - 0.015 15.6 5.4 0.061 13.6 0.2 3.8 3 2 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2914 PF11141.8 EAX68014.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) PKD PF00801.20 EAX68014.1 - 0.081 12.8 0.3 0.56 10.1 0.1 2.5 2 1 0 2 2 2 0 PKD domain bMG6 PF17962.1 EAX68014.1 - 0.099 12.8 0.6 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 He_PIG PF05345.12 EAX68014.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.0 3 0 0 3 3 3 0 Putative Ig domain DNA_pol_B_2 PF03175.13 EAX68016.1 - 1.2e-29 103.6 5.9 1.8e-29 103.0 5.9 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HD_2 PF12917.7 EAX68017.1 - 0.068 12.9 0.1 0.084 12.6 0.1 1.0 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme TPR_MLP1_2 PF07926.12 EAX68018.1 - 0.01 15.9 0.8 0.014 15.4 0.8 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX68018.1 - 0.04 13.7 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 PaRep2a protein Tho2 PF11262.8 EAX68018.1 - 0.053 12.7 3.4 0.058 12.6 3.4 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1731 PF08338.11 EAX68019.1 - 0.14 12.0 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX68021.1 - 1.1e-71 240.3 2.9 1.5e-71 239.8 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX68022.1 - 4e-80 268.8 11.1 5.3e-80 268.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX68022.1 - 0.087 12.3 0.5 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX68023.1 - 5.6e-07 29.3 2.7 5.6e-07 29.3 2.7 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68023.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX68023.1 - 0.00011 22.2 2.2 0.00025 21.1 2.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68023.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EAX68023.1 - 0.00077 19.2 0.1 0.43 10.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_11 PF13086.6 EAX68023.1 - 0.0011 18.8 0.6 0.0019 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68023.1 - 0.0017 18.0 0.5 0.0096 15.6 0.5 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68023.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68023.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68023.1 - 0.076 13.4 0.1 0.62 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68023.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2666 PF10869.8 EAX68023.1 - 0.83 9.9 8.6 7.3 6.8 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PSP PF04046.16 EAX68024.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX68025.1 - 2.8e-111 370.8 7.0 3.1e-111 370.6 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Apolipoprotein PF01442.18 EAX68026.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4106 PF13388.6 EAX68028.1 - 4.2e-156 520.4 42.3 3.3e-155 517.5 42.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX68028.1 - 0.0047 17.2 0.1 0.34 11.2 0.1 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated DNA_pol_B_2 PF03175.13 EAX68029.1 - 9.8e-22 77.4 4.3 1.2e-21 77.2 4.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ResIII PF04851.15 EAX68031.1 - 6.2e-05 23.1 2.9 0.00012 22.2 2.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX68031.1 - 6.2e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX68031.1 - 0.0004 20.2 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68031.1 - 0.0013 18.6 1.4 0.0042 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68031.1 - 0.0019 18.0 0.2 0.21 11.3 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX68031.1 - 0.0075 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68031.1 - 0.047 13.2 0.1 0.069 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX68031.1 - 0.074 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX68031.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX68031.1 - 0.13 12.5 4.9 2.3 8.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX68031.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68031.1 - 0.23 11.2 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_S6e PF01092.19 EAX68033.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e DUF2897 PF11446.8 EAX68034.1 - 0.028 14.3 2.1 0.038 13.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX68035.1 - 4.3e-63 211.5 5.9 4.7e-63 211.4 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68036.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68036.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68036.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain P_proprotein PF01483.20 EAX68037.1 - 0.2 11.7 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Proprotein convertase P-domain DUF4106 PF13388.6 EAX68038.1 - 2.4e-200 666.1 25.3 1.4e-199 663.7 25.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX68038.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3839 PF12943.7 EAX68039.1 - 3.9e-156 517.6 12.8 4.8e-156 517.3 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68039.1 - 0.1 13.1 5.0 2.1 8.9 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX68041.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68041.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68041.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68041.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68041.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68041.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68041.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68041.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68041.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68041.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68041.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68041.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX68042.1 - 4.6e-151 501.0 12.5 5.3e-151 500.9 12.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68042.1 - 0.64 10.5 6.2 1.7 9.1 1.0 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX68042.1 - 1 10.0 4.4 6 7.6 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3944 PF13099.6 EAX68044.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Knl1_RWD_C PF18210.1 EAX68044.1 - 0.19 12.2 6.2 1.3 9.6 3.0 2.4 1 1 2 3 3 3 0 Knl1 RWD C-terminal domain DUF938 PF06080.12 EAX68045.1 - 0.036 13.8 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) DUF4551 PF15087.6 EAX68045.1 - 1.3 7.8 11.1 1.2 7.8 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4407 PF14362.6 EAX68045.1 - 1.4 8.2 12.3 1.7 8.0 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 EAX68045.1 - 5 5.8 11.5 5.2 5.7 11.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EAX68045.1 - 9.5 4.2 13.0 8.6 4.3 13.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trypan_PARP PF05887.11 EAX68046.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tho2 PF11262.8 EAX68049.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 T5orf172 PF10544.9 EAX68050.1 - 1.6e-06 28.6 0.1 4e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX68050.1 - 0.038 13.5 0.3 0.81 9.2 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAX68051.1 - 1.2e-05 24.9 0.1 1.4e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Lysine_decarbox PF03641.14 EAX68051.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 Possible lysine decarboxylase EpuA PF11772.8 EAX68052.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta ANAPC4_WD40 PF12894.7 EAX68053.1 - 0.0019 18.5 0.0 5.7 7.3 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4795 PF16043.5 EAX68054.1 - 0.0022 17.6 4.5 0.0062 16.2 4.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PTR PF12789.7 EAX68054.1 - 0.037 14.1 1.9 0.037 14.1 1.9 4.1 4 1 0 4 4 4 0 Phage tail repeat like T5orf172 PF10544.9 EAX68055.1 - 9.7e-07 29.3 0.3 1.9e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX68056.1 - 2.3e-32 111.2 0.0 3.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain DUF1493 PF07377.12 EAX68057.1 - 0.16 12.4 1.5 0.19 12.2 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX68058.1 - 0.0084 15.8 1.1 0.027 14.2 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4116) UPF0253 PF06786.12 EAX68058.1 - 0.16 12.2 2.2 0.17 12.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) PapD_N PF00345.20 EAX68059.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX68059.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX68061.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain tRNA-synt_1 PF00133.22 EAX68062.1 - 1.6e-62 211.7 1.9 1.1e-60 205.6 1.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EAX68062.1 - 1.2e-07 31.4 0.3 5.8e-05 22.7 0.1 2.2 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 KilA-N PF04383.13 EAX68063.1 - 2.5e-42 143.2 0.7 4.2e-42 142.5 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF1731 PF08338.11 EAX68064.1 - 0.097 12.5 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX68065.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68065.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta YmaF PF12788.7 EAX68066.1 - 0.19 12.3 1.5 11 6.6 0.1 2.1 1 1 0 2 2 2 0 YmaF family FAS_N PF17828.1 EAX68067.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX68067.1 - 0.12 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Pox_A32 PF04665.12 EAX68068.1 - 2e-07 30.8 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68068.1 - 0.0031 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX68068.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX68068.1 - 0.06 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX68068.1 - 0.41 10.8 8.5 5.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX68069.1 - 7.2e-69 231.1 3.3 8.6e-69 230.8 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68069.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX68069.1 - 0.12 10.8 1.1 0.16 10.3 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase KilA-N PF04383.13 EAX68071.1 - 9.2e-25 86.7 0.1 1e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX68072.1 - 2e-41 140.4 0.1 2e-41 140.4 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX68072.1 - 0.021 14.8 6.4 0.037 14.0 6.4 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FPN1 PF06963.12 EAX68072.1 - 0.22 10.0 0.2 0.31 9.6 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ResIII PF04851.15 EAX68075.1 - 5.4e-05 23.3 2.3 9.9e-05 22.4 2.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68075.1 - 0.00033 20.5 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68075.1 - 0.00035 20.8 0.0 0.00064 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68075.1 - 0.0007 19.5 1.0 0.0022 17.8 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68075.1 - 0.007 16.7 0.0 0.0094 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68075.1 - 0.034 13.9 0.2 0.21 11.3 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX68075.1 - 0.044 13.2 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX68075.1 - 0.063 13.0 0.2 0.093 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX68075.1 - 0.076 12.7 0.5 0.14 11.8 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX68075.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68075.1 - 0.24 11.1 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX68075.1 - 0.39 11.0 3.4 4.7 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX68075.1 - 0.76 10.2 4.1 0.32 11.4 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Tubulin PF00091.25 EAX68076.1 - 2.5e-67 226.9 0.0 3.6e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX68076.1 - 5e-40 136.6 0.0 8e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAX68076.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAX68076.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p NDUFB10 PF10249.9 EAX68078.1 - 0.034 14.6 0.7 7.7 7.0 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 DNA_pol_B_2 PF03175.13 EAX68079.1 - 6.7e-09 35.1 0.9 9.1e-09 34.7 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68079.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX68079.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 TMP PF05017.14 EAX68082.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68083.1 - 0.19 11.6 2.7 0.21 11.5 0.3 2.1 2 1 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX68084.1 - 2.3e-07 31.3 0.3 4.8e-07 30.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX68084.1 - 0.13 12.9 0.4 0.36 11.5 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 PapD_N PF00345.20 EAX68086.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX68086.1 - 0.071 13.1 0.5 0.1 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol_B_2 PF03175.13 EAX68087.1 - 1.1e-11 44.3 0.2 2.6e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68087.1 - 0.051 12.9 0.1 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX68088.1 - 8e-82 274.3 3.3 9.8e-82 274.0 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX68088.1 - 0.12 13.0 0.9 0.25 12.0 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX68089.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX68090.1 - 2.2e-157 521.7 15.2 2.8e-157 521.4 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68090.1 - 0.88 10.1 7.6 2.3 8.8 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase 2_5_RNA_ligase2 PF13563.6 EAX68091.1 - 0.18 11.7 0.0 8.7 6.2 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily AAA_22 PF13401.6 EAX68092.1 - 7.2e-05 23.1 0.1 0.00041 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX68092.1 - 7.3e-05 22.8 2.5 0.00013 22.0 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX68092.1 - 8.5e-05 22.4 0.4 0.35 10.6 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX68092.1 - 0.00046 20.0 0.0 0.00087 19.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68092.1 - 0.00071 19.4 0.8 0.0019 18.0 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68092.1 - 0.011 16.0 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX68092.1 - 0.058 13.1 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX68092.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX68092.1 - 0.078 13.4 0.1 0.44 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX68092.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX68092.1 - 0.32 11.3 5.3 6.9 7.0 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX68094.1 - 0.015 15.7 0.9 0.032 14.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX68096.1 - 4.7e-152 504.3 10.3 5.5e-152 504.1 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX68096.1 - 0.055 13.0 1.6 0.096 12.2 0.3 1.8 1 1 1 2 2 2 0 Z1 domain Fez1 PF06818.15 EAX68096.1 - 0.09 13.2 1.7 0.57 10.6 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX68096.1 - 0.32 11.5 6.7 1.1 9.7 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX68098.1 - 8.7e-07 28.6 0.0 9.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein FAS_N PF17828.1 EAX68099.1 - 0.0084 16.1 0.1 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX68100.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX68101.1 - 2.4e-41 140.1 0.9 5.1e-41 139.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX68102.1 - 1.5e-61 207.3 12.8 4.5e-60 202.5 12.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68102.1 - 0.098 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX68104.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68104.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68104.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68104.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68104.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68104.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68104.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68104.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68104.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68104.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68104.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68104.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) FAS_N PF17828.1 EAX68105.1 - 0.0065 16.5 0.2 0.0088 16.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX68106.1 - 2.3e-157 521.7 11.5 2.6e-157 521.5 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68106.1 - 0.13 12.8 5.4 1.8 9.1 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX68106.1 - 0.33 11.3 3.2 8.2 6.8 0.1 3.2 3 2 1 4 4 4 0 Tup N-terminal DUF3839 PF12943.7 EAX68107.1 - 5.2e-157 520.5 11.9 6.2e-157 520.3 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX68107.1 - 0.049 13.9 0.8 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX68107.1 - 0.1 13.0 0.2 0.99 9.8 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX68107.1 - 0.38 11.2 5.8 4.7 7.7 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4312 PF14189.6 EAX68108.1 - 0.00018 21.4 6.3 0.037 14.0 0.1 4.4 1 1 4 5 5 5 1 Domain of unknown function (DUF4312) Retinin_C PF04527.12 EAX68108.1 - 0.00037 20.7 25.8 3.4 8.0 0.6 5.2 5 0 0 5 5 5 5 Drosophila Retinin like protein Cas_Csa5 PF09702.10 EAX68108.1 - 0.001 19.3 3.6 35 4.7 0.1 4.6 1 1 4 5 5 5 0 CRISPR-associated protein (Cas_Csa5) Phage_holin_6_1 PF09682.10 EAX68108.1 - 0.0091 16.4 3.7 45 4.5 0.0 4.3 1 1 4 5 5 5 0 Bacteriophage holin of superfamily 6 (Holin_LLH) FliG_C PF01706.16 EAX68108.1 - 0.022 14.9 11.7 32 4.8 0.1 4.9 1 1 4 5 5 5 0 FliG C-terminal domain DUF4359 PF14271.6 EAX68108.1 - 0.27 12.0 15.8 8 7.3 1.6 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4359) Pro_dh-DNA_bdg PF14850.6 EAX68108.1 - 0.35 11.4 10.2 2.5 8.7 1.3 2.7 1 1 3 4 4 4 0 DNA-binding domain of Proline dehydrogenase UK PF02512.14 EAX68108.1 - 0.52 10.9 14.0 45 4.7 0.3 4.6 1 1 4 5 5 5 0 Virulence determinant TEX13 PF15186.6 EAX68108.1 - 1 9.1 7.9 9.2 5.9 0.5 2.7 1 1 3 4 4 4 0 Testis-expressed sequence 13 protein family Pox_D5 PF03288.16 EAX68109.1 - 2.1e-05 24.9 2.6 0.00011 22.7 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68109.1 - 0.047 14.3 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Trypan_PARP PF05887.11 EAX68110.1 - 0.088 12.8 7.6 0.13 12.2 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68110.1 - 4.3 7.8 6.0 6.4 7.2 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_D5 PF03288.16 EAX68111.1 - 0.00084 19.8 2.7 0.0054 17.2 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX68111.1 - 0.039 13.0 1.3 0.052 12.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Trypan_PARP PF05887.11 EAX68112.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68112.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX68113.1 - 1.4e-149 496.1 11.1 1.6e-149 496.0 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ArsA_ATPase PF02374.15 EAX68113.1 - 0.057 12.6 1.6 0.15 11.2 0.1 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase LD_cluster2 PF18163.1 EAX68113.1 - 0.13 11.8 0.1 0.64 9.5 0.0 2.0 1 1 1 2 2 2 0 SLOG cluster2 KELK PF15796.5 EAX68113.1 - 0.27 11.7 3.8 3.6 8.1 0.3 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX68113.1 - 0.54 10.6 2.9 2.3 8.5 0.1 2.9 2 1 0 2 2 2 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX68114.1 - 0.00014 21.4 0.4 0.00014 21.4 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX68114.1 - 0.068 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX68115.1 - 2.7e-07 30.3 1.2 4.4e-07 29.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX68116.1 - 6.8e-40 135.4 0.3 1.9e-39 134.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX68116.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF2939 PF11159.8 EAX68117.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68117.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMP PF05017.14 EAX68118.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68119.1 - 0.063 13.2 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX68121.1 - 9.6e-07 28.5 1.9 9.6e-07 28.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68121.1 - 3e-05 24.3 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68121.1 - 3.8e-05 23.5 0.3 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68121.1 - 0.00019 21.5 3.7 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68121.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68121.1 - 0.0017 18.2 0.8 0.005 16.7 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68121.1 - 0.0019 17.9 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68121.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68121.1 - 0.067 12.8 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX68121.1 - 0.079 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX68121.1 - 0.084 13.3 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68121.1 - 0.088 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68121.1 - 0.39 11.0 4.1 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX68122.1 - 0.00024 21.6 0.3 0.00056 20.4 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX68122.1 - 0.011 15.3 1.0 0.13 11.8 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX68122.1 - 0.014 15.2 0.1 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 KilA-N domain VirE PF05272.11 EAX68123.1 - 1e-05 25.4 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX68123.1 - 0.058 13.8 0.4 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF4108 PF13390.6 EAX68124.1 - 3.2e-55 186.0 5.7 3.5e-55 185.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX68125.1 - 0.41 10.4 2.5 0.41 10.4 2.5 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX68125.1 - 0.65 9.9 4.9 0.79 9.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S49_N PF08496.10 EAX68125.1 - 2 8.5 5.2 1.9 8.5 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3035 PF11233.8 EAX68126.1 - 0.013 15.7 4.5 0.018 15.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF2486 PF10667.9 EAX68126.1 - 0.018 15.3 7.9 0.021 15.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) PdaC PF13739.6 EAX68127.1 - 0.15 13.1 1.1 0.18 12.8 1.1 1.1 1 0 0 1 1 1 0 Deacetylase PdaC DUF4304 PF14137.6 EAX68128.1 - 0.018 15.2 0.3 0.018 15.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4304) Ribosomal_S15 PF00312.22 EAX68128.1 - 0.22 11.8 3.5 1.1 9.5 0.8 2.5 2 0 0 2 2 2 0 Ribosomal protein S15 DBP10CT PF08147.12 EAX68128.1 - 0.35 11.1 8.7 0.78 10.0 0.1 2.9 3 0 0 3 3 3 0 DBP10CT (NUC160) domain Pox_A32 PF04665.12 EAX68129.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68129.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68129.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68129.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX68130.1 - 0.015 15.7 0.7 0.029 14.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX68131.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX68132.1 - 1.8e-07 30.9 0.2 1.3e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX68132.1 - 0.066 12.8 0.1 1.5 8.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX68132.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX68132.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_D5 PF03288.16 EAX68133.1 - 5.9e-06 26.7 0.5 8.5e-06 26.2 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68133.1 - 0.039 14.6 0.1 0.052 14.2 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68133.1 - 0.073 13.1 0.4 0.12 12.4 0.4 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX68134.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX68135.1 - 0.56 10.1 3.2 1 9.3 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) VirE PF05272.11 EAX68137.1 - 1.7e-05 24.7 0.1 2.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX68137.1 - 4.6e-05 23.8 2.0 0.00027 21.4 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX68137.1 - 0.044 14.2 0.3 0.15 12.4 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF3198 PF11433.8 EAX68137.1 - 0.13 12.2 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Pox_A32 PF04665.12 EAX68138.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68138.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68138.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68138.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68138.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68138.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68138.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68138.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68138.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68138.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68138.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68138.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX68140.1 - 7.5e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain WRKY PF03106.15 EAX68141.1 - 0.028 14.6 1.1 0.028 14.6 1.1 2.7 2 2 1 3 3 3 0 WRKY DNA -binding domain Pox_A32 PF04665.12 EAX68143.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68143.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68143.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68143.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) TMP PF05017.14 EAX68144.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX68146.1 - 0.023 15.2 0.6 0.045 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX68147.1 - 0.052 14.0 0.4 0.11 12.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX68148.1 - 1.9e-62 209.4 6.5 2.1e-62 209.3 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX68149.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX68149.1 - 2.6 8.0 5.9 5.8 6.9 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF257 PF03192.13 EAX68150.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX68150.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PTR PF12789.7 EAX68151.1 - 2.5e-61 203.6 37.7 1.9e-34 117.5 16.2 4.1 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX68151.1 - 0.0091 15.7 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX68151.1 - 0.46 10.9 5.3 21 5.5 0.1 4.1 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain ResIII PF04851.15 EAX68153.1 - 2.4e-05 24.4 1.4 4.2e-05 23.6 1.4 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68153.1 - 0.00025 20.9 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68153.1 - 0.00041 20.6 0.0 0.00064 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68153.1 - 0.0012 18.7 0.2 0.0021 17.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68153.1 - 0.0056 17.0 0.0 0.0075 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68153.1 - 0.031 13.7 0.1 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX68153.1 - 0.057 13.1 0.6 0.084 12.5 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX68153.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX68153.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68153.1 - 0.16 11.6 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX68153.1 - 0.7 10.3 4.0 0.33 11.4 0.7 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Amidase02_C PF12123.8 EAX68154.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68155.1 - 2.6e-29 102.4 6.6 4e-29 101.8 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX68155.1 - 0.13 12.7 1.1 0.88 10.1 0.2 2.1 1 1 0 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX68155.1 - 0.29 11.5 1.4 2.9 8.3 0.6 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX68156.1 - 1.1e-118 395.0 8.2 1.3e-118 394.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX68156.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX68156.1 - 0.19 12.0 4.1 0.56 10.5 0.1 2.9 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX68156.1 - 0.23 12.0 2.1 1.1 9.7 1.3 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX68157.1 - 1e-59 201.9 3.2 1.2e-59 201.7 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NdhO PF11910.8 EAX68157.1 - 0.087 13.0 0.0 0.23 11.6 0.0 1.7 1 1 1 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O MULE PF10551.9 EAX68158.1 - 1.6e-05 25.2 0.1 3.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX68158.1 - 0.041 14.6 0.1 0.084 13.6 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Ank PF00023.30 EAX68159.1 - 1.4e-52 174.0 6.7 1e-07 32.1 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX68159.1 - 8.8e-43 144.2 9.2 5.1e-08 33.3 0.1 7.2 3 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX68159.1 - 5e-42 142.4 8.9 1.7e-16 60.5 0.5 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX68159.1 - 2.9e-36 119.4 14.3 3e-05 24.1 0.1 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX68159.1 - 4.7e-36 122.4 2.4 5.7e-11 42.4 0.1 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX68159.1 - 1.1e-25 89.3 7.3 1.1e-25 89.3 7.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAX68159.1 - 0.00014 22.1 0.0 7.2 6.8 0.0 4.6 2 1 4 6 6 5 1 Centrosomal spindle body, CEP44 MetallophosN PF16371.5 EAX68159.1 - 0.0007 19.8 0.0 4.6 7.6 0.0 4.3 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase Clathrin PF00637.20 EAX68159.1 - 0.00097 19.0 3.4 4.9 7.0 0.3 4.7 1 1 3 4 4 4 2 Region in Clathrin and VPS Ribosomal_S6 PF01250.17 EAX68159.1 - 0.001 19.3 0.0 24 5.3 0.0 4.2 2 1 3 5 5 5 0 Ribosomal protein S6 GATase_7 PF13537.6 EAX68159.1 - 0.0017 18.3 0.0 33 4.4 0.0 4.6 3 1 2 5 5 5 0 Glutamine amidotransferase domain ThiS-like PF14453.6 EAX68159.1 - 0.0026 17.8 5.0 11 6.1 0.0 5.2 2 1 4 6 6 5 0 ThiS-like ubiquitin NMT1_2 PF13379.6 EAX68159.1 - 0.004 16.9 0.0 2 8.0 0.0 3.0 1 1 2 3 3 3 1 NMT1-like family Arylesterase PF01731.20 EAX68159.1 - 0.052 13.8 6.0 45 4.4 0.0 4.8 1 1 5 6 6 6 0 Arylesterase Phage-tail_1 PF09097.10 EAX68159.1 - 0.32 10.8 4.2 1.2 8.9 0.3 2.8 1 1 2 3 3 3 0 Baseplate structural protein, domain 1 Myb_DNA-bind_6 PF13921.6 EAX68159.1 - 0.4 11.0 10.1 15 6.0 0.3 4.2 3 1 2 5 5 4 0 Myb-like DNA-binding domain PSP PF04046.16 EAX68160.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68161.1 - 0.02 15.4 5.6 2.9 8.9 0.3 3.4 3 1 0 3 3 3 0 TMP repeat DDE_1 PF03184.19 EAX68162.1 - 9e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Styelin PF17562.2 EAX68162.1 - 0.0052 17.1 0.8 0.0097 16.2 0.8 1.4 1 0 0 1 1 1 1 Styelin dsDNA_bind PF01984.20 EAX68162.1 - 0.1 12.9 0.4 0.16 12.3 0.4 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain TMP PF05017.14 EAX68163.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68164.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX68165.1 - 5.7e-07 29.2 0.1 6.8e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Amidase02_C PF12123.8 EAX68167.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68168.1 - 3.2e-154 511.4 14.7 3.9e-154 511.1 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX68168.1 - 1.1 10.3 4.1 0.65 11.0 0.8 2.3 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX68168.1 - 8.6 6.9 9.7 2.4 8.7 1.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX68170.1 - 1.9e-41 140.4 0.7 3.8e-41 139.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX68171.1 - 0.0083 15.8 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68172.1 - 5.6e-48 163.5 2.8 6.4e-48 163.3 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX68172.1 - 0.16 12.6 2.2 1.1 9.9 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX68173.1 - 4e-29 101.8 6.7 6.3e-29 101.1 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX68173.1 - 0.12 12.9 1.3 0.71 10.4 0.2 2.1 1 1 0 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX68173.1 - 0.29 11.6 1.3 2.9 8.3 0.6 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF1731 PF08338.11 EAX68174.1 - 0.1 12.5 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX68175.1 - 3.6e-07 29.9 0.3 4.3e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Phage_fiber PF03335.13 EAX68176.1 - 6.1 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Gly-zipper_Omp PF13488.6 EAX68177.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX68177.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF4795 PF16043.5 EAX68178.1 - 0.01 15.4 4.2 0.036 13.7 4.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX68178.1 - 5.5 7.4 5.9 29 5.2 0.5 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX68179.1 - 6.6e-08 32.3 0.9 8e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68179.1 - 0.003 17.2 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68179.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68179.1 - 0.091 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX68179.1 - 0.13 12.7 1.3 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) KilA-N PF04383.13 EAX68181.1 - 2e-43 146.8 0.1 3.2e-43 146.1 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain HAUS-augmin3 PF14932.6 EAX68182.1 - 0.009 15.6 1.7 0.013 15.1 1.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Lipoxygenase PF00305.19 EAX68182.1 - 0.049 12.1 0.7 0.065 11.6 0.7 1.1 1 0 0 1 1 1 0 Lipoxygenase Arm-DNA-bind_5 PF17293.2 EAX68182.1 - 0.36 11.3 7.3 2.3 8.7 7.3 2.2 1 1 0 1 1 1 0 Arm DNA-binding domain DNA_pol_B_2 PF03175.13 EAX68185.1 - 2.8e-24 85.8 7.6 1.2e-23 83.8 7.6 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68185.1 - 0.021 14.8 0.0 0.79 9.7 0.0 3.0 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX68186.1 - 2.4e-157 521.6 14.6 3.1e-157 521.3 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68186.1 - 0.61 10.6 6.9 2.3 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX68189.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68189.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX68190.1 - 0.051 14.0 0.5 0.1 13.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX68190.1 - 0.42 10.7 3.6 10 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Ank_2 PF12796.7 EAX68191.1 - 5.6e-33 113.4 1.7 3.2e-12 46.8 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX68191.1 - 9e-32 109.1 3.7 3.4e-08 33.9 0.2 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX68191.1 - 1.6e-29 101.5 0.1 1.1e-06 28.7 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX68191.1 - 4.3e-26 88.1 1.4 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX68191.1 - 1.2e-20 72.9 3.1 0.00026 21.3 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat DUF3447 PF11929.8 EAX68191.1 - 0.0035 17.2 0.7 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DDR PF08841.10 EAX68193.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX68193.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX68194.1 - 0.042 13.8 12.0 0.043 13.8 12.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68194.1 - 2.7 8.4 6.8 3 8.3 6.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX68195.1 - 1.4e-21 77.0 5.2 1.7e-21 76.6 5.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68195.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4106 PF13388.6 EAX68196.1 - 5.4e-216 717.7 21.5 6.2e-216 717.5 21.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.10 EAX68196.1 - 4.7 5.8 7.4 7.1 5.2 7.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDE_1 PF03184.19 EAX68197.1 - 2e-13 50.4 0.0 3.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 2_5_RNA_ligase2 PF13563.6 EAX68198.1 - 0.035 14.0 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Col_cuticle_N PF01484.17 EAX68198.1 - 0.16 12.1 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF4107 PF13389.6 EAX68199.1 - 1.7e-71 239.6 3.8 2.3e-71 239.2 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX68200.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX68202.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68203.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX68204.1 - 0.0075 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX68205.1 - 1.5e-16 60.2 2.0 1.5e-16 60.2 2.0 3.1 4 0 0 4 4 4 1 Phage tail repeat like Trypan_PARP PF05887.11 EAX68206.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68206.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1493 PF07377.12 EAX68207.1 - 0.048 14.1 0.2 0.089 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Big_5 PF13205.6 EAX68209.1 - 0.0058 17.3 1.6 0.044 14.5 0.9 2.2 2 0 0 2 2 2 1 Bacterial Ig-like domain SAVED PF18145.1 EAX68209.1 - 0.17 11.6 1.6 8.5 6.1 0.0 2.8 2 1 1 3 3 3 0 SMODS-associated and fused to various effectors sensor domain DUF3839 PF12943.7 EAX68210.1 - 7.6e-25 87.8 4.5 1.2e-24 87.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX68211.1 - 6.4e-87 285.6 67.2 7.4e-32 109.2 15.7 6.2 2 2 4 6 6 6 4 Phage tail repeat like HS1_rep PF02218.15 EAX68211.1 - 0.00021 21.5 0.0 80 3.7 0.0 4.9 5 0 0 5 5 5 0 Repeat in HS1/Cortactin HigB_toxin PF09907.9 EAX68211.1 - 0.0028 17.8 0.4 5.2 7.4 0.0 3.4 1 1 3 4 4 4 1 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Apolipoprotein PF01442.18 EAX68211.1 - 0.0032 17.4 1.4 0.013 15.4 1.4 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain AviRa PF11599.8 EAX68211.1 - 0.35 10.3 5.2 0.69 9.3 0.7 2.4 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX68211.1 - 1 9.7 13.8 21 5.5 0.4 5.5 1 1 5 6 6 6 0 TFIIH p62 subunit, N-terminal domain PapD_N PF00345.20 EAX68212.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX68212.1 - 0.045 13.7 0.6 0.066 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_D5 PF03288.16 EAX68213.1 - 8.1e-05 23.0 2.2 0.00063 20.2 2.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Pox_A32 PF04665.12 EAX68214.1 - 3.2e-05 23.5 2.7 3.2e-05 23.5 2.7 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX68214.1 - 0.0023 17.9 0.2 0.0062 16.6 0.2 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX68214.1 - 0.0084 15.7 0.3 0.017 14.7 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX68214.1 - 0.04 14.2 1.1 0.11 12.8 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX68214.1 - 0.05 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DDE_1 PF03184.19 EAX68215.1 - 5.3e-09 36.0 0.0 8.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ResIII PF04851.15 EAX68217.1 - 6.7e-05 23.0 2.5 0.00013 22.0 2.5 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68217.1 - 0.00033 20.5 0.0 0.00048 19.9 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68217.1 - 0.00041 20.6 0.0 0.00069 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68217.1 - 0.00048 20.0 1.1 0.0015 18.4 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68217.1 - 0.0069 16.7 0.0 0.0094 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68217.1 - 0.039 13.4 0.1 0.09 12.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX68217.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68217.1 - 0.24 11.1 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX68217.1 - 0.56 10.7 3.4 0.32 11.4 1.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 UCH PF00443.29 EAX68218.1 - 0.0023 17.5 0.2 0.0025 17.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4108 PF13390.6 EAX68219.1 - 1.3e-62 209.9 5.9 1.5e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68220.1 - 1.7e-05 25.3 2.6 8.3e-05 23.0 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68220.1 - 0.042 14.5 0.1 0.085 13.5 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68220.1 - 0.092 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Amidase02_C PF12123.8 EAX68221.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX68221.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Amidase02_C PF12123.8 EAX68222.1 - 0.0034 17.0 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF2960 PF11173.8 EAX68223.1 - 0.066 13.7 0.3 0.17 12.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Pox_D5 PF03288.16 EAX68224.1 - 7.8e-06 26.3 2.9 4.5e-05 23.8 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68224.1 - 0.02 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68224.1 - 0.06 13.3 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX68225.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX68226.1 - 2.9 8.2 9.8 2.9 8.1 9.8 1.0 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PTR PF12789.7 EAX68228.1 - 2.3e-23 82.0 13.8 1.5e-21 76.2 8.7 4.2 4 1 0 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX68228.1 - 0.0088 16.6 7.0 0.25 11.9 0.9 3.5 4 0 0 4 4 4 2 YmaF family DUF4795 PF16043.5 EAX68228.1 - 0.039 13.6 14.4 0.085 12.4 2.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Lectin_legB PF00139.19 EAX68229.1 - 0.0023 17.5 0.7 0.17 11.4 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX68229.1 - 0.0069 16.9 0.3 0.014 16.0 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX68229.1 - 0.016 15.1 0.2 0.036 13.9 0.2 1.8 1 1 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX68230.1 - 6.2e-25 88.1 4.9 8.7e-25 87.6 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PSP PF04046.16 EAX68231.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX68232.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68232.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68232.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68232.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX68235.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4106 PF13388.6 EAX68239.1 - 4.9e-08 32.6 5.4 5.6e-08 32.4 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Radial_spoke_3 PF06098.11 EAX68240.1 - 9.9e-12 44.7 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 Pox_A32 PF04665.12 EAX68241.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein SelP_N PF04592.14 EAX68242.1 - 0.82 9.0 18.3 1.1 8.6 18.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EAX68242.1 - 2.1 6.8 11.3 2.4 6.6 11.3 1.0 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EAX68242.1 - 3.4 6.8 7.8 3.7 6.7 7.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_B_2 PF03175.13 EAX68244.1 - 2.7e-23 82.6 4.4 3.5e-23 82.2 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX68245.1 - 5.2e-42 142.2 0.7 1e-41 141.3 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX68245.1 - 0.0039 17.3 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) GPS2_interact PF15784.5 EAX68248.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68248.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX68249.1 - 3.2e-07 30.1 0.3 3.7e-07 29.8 0.3 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX68251.1 - 0.032 14.7 0.4 0.06 13.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX68251.1 - 0.43 10.7 3.9 7.8 6.6 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF257 PF03192.13 EAX68252.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX68252.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Laminin_I PF06008.14 EAX68253.1 - 0.0028 17.4 0.2 0.0029 17.3 0.2 1.0 1 0 0 1 1 1 1 Laminin Domain I Sec34 PF04136.15 EAX68253.1 - 0.015 15.2 1.3 0.017 15.0 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family Synaptobrevin PF00957.21 EAX68253.1 - 4 7.3 4.8 17 5.3 0.4 2.0 1 1 1 2 2 2 0 Synaptobrevin FAS_N PF17828.1 EAX68254.1 - 0.0065 16.5 0.2 0.0088 16.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX68255.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68255.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX68258.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX68260.1 - 1.1e-24 87.2 7.6 1.1e-23 83.8 7.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68260.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX68260.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 KilA-N PF04383.13 EAX68261.1 - 1e-11 44.7 1.1 1e-11 44.7 1.1 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX68262.1 - 6.5e-40 137.1 3.8 9.4e-40 136.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX68262.1 - 0.064 12.4 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PTR PF12789.7 EAX68263.1 - 4.9e-158 513.3 114.6 3.5e-32 110.3 15.4 6.0 2 2 5 7 7 7 6 Phage tail repeat like HigB_toxin PF09907.9 EAX68263.1 - 0.0087 16.3 0.7 16 5.8 0.0 3.5 1 1 2 3 3 3 1 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system AviRa PF11599.8 EAX68263.1 - 0.18 11.3 5.2 0.6 9.5 0.6 2.5 1 1 2 3 3 3 0 RRNA methyltransferase AviRa DUF2785 PF10978.8 EAX68263.1 - 2.3 8.0 8.9 1.9 8.2 4.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) TMP PF05017.14 EAX68266.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX68267.1 - 0.039 14.4 0.4 0.072 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX68267.1 - 0.36 10.9 3.3 9.7 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX68268.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68268.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX68268.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX68268.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68268.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX68268.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF1493 PF07377.12 EAX68269.1 - 0.021 15.3 0.5 0.045 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF846 PF05832.12 EAX68270.1 - 0.058 13.4 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF4107 PF13389.6 EAX68271.1 - 2.9e-66 222.6 13.3 1.4e-64 217.1 13.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68271.1 - 0.063 13.6 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF745 PF05335.13 EAX68274.1 - 0.0022 17.8 16.1 0.0066 16.2 14.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF745) SesA PF17107.5 EAX68274.1 - 0.0099 16.1 5.8 0.0099 16.1 5.8 1.9 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Tropomyosin_1 PF12718.7 EAX68274.1 - 0.01 16.0 26.2 0.029 14.5 8.5 2.9 1 1 2 3 3 3 0 Tropomyosin like SKA1 PF07160.12 EAX68274.1 - 0.075 12.9 16.1 0.32 10.8 15.8 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 EAX68274.1 - 0.083 13.1 25.8 0.32 11.2 9.6 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Cast PF10174.9 EAX68274.1 - 0.13 10.4 24.4 0.088 11.0 22.8 1.4 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SlyX PF04102.12 EAX68274.1 - 0.19 12.4 19.4 1.2 9.8 1.5 5.0 1 1 4 5 5 5 0 SlyX Myosin_tail_1 PF01576.19 EAX68274.1 - 0.22 9.3 26.5 0.27 9.0 26.5 1.0 1 0 0 1 1 1 0 Myosin tail Golgin_A5 PF09787.9 EAX68274.1 - 0.24 10.8 29.6 0.042 13.3 24.3 2.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tropomyosin PF00261.20 EAX68274.1 - 0.29 10.5 25.0 0.72 9.2 3.6 3.3 1 1 1 3 3 3 0 Tropomyosin Lebercilin PF15619.6 EAX68274.1 - 0.4 10.3 27.5 15 5.1 27.5 2.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CTU2 PF10288.9 EAX68274.1 - 1 9.6 0.0 1 9.6 0.0 2.8 1 1 1 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PCRF PF03462.18 EAX68274.1 - 1.2 9.0 14.7 0.57 10.0 9.5 2.1 1 1 1 2 2 2 0 PCRF domain Csm1_N PF18504.1 EAX68274.1 - 1.7 9.1 24.2 1.4 9.3 1.6 4.7 4 1 1 5 5 5 0 Csm1 N-terminal domain OmpH PF03938.14 EAX68274.1 - 1.7 9.0 19.1 2.3 8.5 13.3 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 EAX68274.1 - 1.7 8.7 28.3 4.9 7.2 15.1 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 EAX68274.1 - 2 8.0 21.0 12 5.6 9.0 3.1 1 1 2 3 3 3 0 GrpE PKcGMP_CC PF16808.5 EAX68274.1 - 2.2 8.2 11.2 0.45 10.4 0.3 3.8 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 EAX68274.1 - 3.1 7.9 28.6 4.1 7.5 5.1 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Peptidase_S46 PF10459.9 EAX68274.1 - 3.2 6.3 10.4 3.6 6.1 10.4 1.1 1 0 0 1 1 1 0 Peptidase S46 Baculo_PEP_C PF04513.12 EAX68274.1 - 3.7 7.6 9.9 8.3 6.5 2.0 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EAX68274.1 - 3.9 6.3 27.9 0.23 10.3 10.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Bap31_Bap29_C PF18035.1 EAX68274.1 - 6.4 6.9 10.9 0.6 10.1 0.7 3.5 2 2 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 EAX68274.1 - 7.7 5.8 14.4 22 4.3 13.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EAX68274.1 - 7.8 6.3 23.8 6.1 6.6 11.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_HK97_TLTM PF06120.11 EAX68274.1 - 8.7 5.4 14.4 68 2.5 14.4 2.0 1 1 0 1 1 1 0 Tail length tape measure protein DUF2939 PF11159.8 EAX68275.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68275.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68276.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX68278.1 - 1.3e-39 135.9 7.1 4.4e-39 134.2 7.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68278.1 - 0.064 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta 1-cysPrx_C PF10417.9 EAX68279.1 - 1.9e-06 27.6 0.2 2.8e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 EAX68279.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 2 0 0 2 2 2 0 AhpC/TSA family DUF3839 PF12943.7 EAX68287.1 - 3.6e-93 311.5 8.2 4.1e-93 311.3 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX68289.1 - 4.7e-67 225.2 2.4 6.3e-67 224.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68289.1 - 0.1 13.0 0.3 0.19 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta FAS_N PF17828.1 EAX68292.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AAA_11 PF13086.6 EAX68294.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX68294.1 - 0.0027 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68294.1 - 0.0037 17.6 0.0 0.0055 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX68294.1 - 0.0051 16.8 0.0 0.0065 16.5 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX68294.1 - 0.02 14.4 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX68294.1 - 0.049 13.2 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX68294.1 - 0.081 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX68294.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX68294.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Amidase02_C PF12123.8 EAX68295.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX68297.1 - 0.15 11.9 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TMP PF05017.14 EAX68298.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68299.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX68300.1 - 3e-76 254.2 11.4 3.4e-76 254.0 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAX68300.1 - 0.42 11.6 3.1 1 10.4 3.1 1.6 1 0 0 1 1 1 0 Deacetylase PdaC Laminin_I PF06008.14 EAX68301.1 - 0.00031 20.5 3.7 0.0014 18.4 3.7 1.8 1 1 0 1 1 1 1 Laminin Domain I DUF3450 PF11932.8 EAX68301.1 - 0.013 14.8 4.3 0.017 14.4 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 EAX68301.1 - 0.014 15.2 8.1 0.093 12.6 3.0 2.2 1 1 1 2 2 2 0 Sec34-like family SNAP PF14938.6 EAX68301.1 - 0.048 13.1 1.3 0.066 12.6 1.3 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3552 PF12072.8 EAX68301.1 - 0.049 13.0 0.2 0.5 9.8 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) UPF0449 PF15136.6 EAX68301.1 - 0.054 14.0 2.3 0.36 11.3 2.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 EAX68301.1 - 0.055 13.9 0.4 0.65 10.5 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EAX68301.1 - 0.083 13.4 1.5 0.11 13.0 1.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region KASH_CCD PF14662.6 EAX68301.1 - 0.18 11.6 3.0 0.32 10.8 3.0 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EAX68301.1 - 0.21 10.4 2.4 0.37 9.6 2.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EAX68301.1 - 0.34 10.4 5.7 0.44 10.1 5.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 EAX68301.1 - 0.38 10.8 8.4 0.62 10.1 8.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 EAX68301.1 - 0.43 10.8 3.9 1.1 9.5 3.9 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Synaptobrevin PF00957.21 EAX68301.1 - 0.7 9.7 10.4 1.8 8.4 0.4 3.4 1 1 1 2 2 2 0 Synaptobrevin Syntaxin-6_N PF09177.11 EAX68301.1 - 1.2 9.7 6.7 4.6 7.9 2.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATG16 PF08614.11 EAX68301.1 - 6.3 7.0 12.0 10 6.3 12.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PapD_N PF00345.20 EAX68303.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX68303.1 - 0.029 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX68304.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) KilA-N PF04383.13 EAX68306.1 - 9.9e-07 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX68307.1 - 1.9e-127 423.7 5.5 2.1e-127 423.5 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68307.1 - 0.035 14.6 0.8 1.1 9.8 0.3 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX68309.1 - 4.5e-55 185.5 7.4 5e-55 185.4 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX68310.1 - 2.3e-37 126.8 23.4 7.2e-34 115.7 15.4 4.2 2 2 1 3 3 3 2 Phage tail repeat like DUF4795 PF16043.5 EAX68310.1 - 0.0017 18.0 8.4 0.029 14.0 4.8 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX68312.1 - 5.6e-07 29.3 3.1 5.6e-07 29.3 3.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68312.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68312.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68312.1 - 0.00011 22.3 2.7 0.00022 21.3 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68312.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68312.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68312.1 - 0.002 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68312.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX68312.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX68312.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68312.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68312.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68312.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX68313.1 - 4.5e-149 494.5 14.4 5.5e-149 494.2 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ndc1_Nup PF09531.10 EAX68315.1 - 0.4 9.3 0.6 0.52 8.9 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2939 PF11159.8 EAX68316.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68316.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68317.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DASH_Dam1 PF08653.10 EAX68319.1 - 0.13 12.1 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Pox_A32 PF04665.12 EAX68322.1 - 2.4e-07 30.5 0.3 8.8e-07 28.6 0.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein PBAN PF05874.11 EAX68322.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Pox_A32 PF04665.12 EAX68324.1 - 2e-07 30.7 0.5 1.2e-06 28.1 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX68324.1 - 0.034 13.8 0.1 0.75 9.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Amidase02_C PF12123.8 EAX68325.1 - 0.006 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1493 PF07377.12 EAX68326.1 - 0.015 15.7 0.5 0.028 14.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX68326.1 - 0.75 9.9 4.5 8 6.6 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein RGS12_us1 PF16613.5 EAX68329.1 - 0.11 12.8 4.0 0.13 12.6 4.0 1.1 1 0 0 1 1 1 0 Unstructured region of RGS12 GGDEF PF00990.21 EAX68329.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX68330.1 - 3.5e-61 205.3 7.8 3.9e-61 205.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX68331.1 - 0.41 11.0 2.6 0.48 10.8 2.6 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX68331.1 - 0.77 9.7 3.2 1.6 8.7 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX68332.1 - 1.7e-64 216.0 5.9 1.9e-64 215.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX68332.1 - 0.038 14.2 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX68333.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68333.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68333.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68333.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) GPS2_interact PF15784.5 EAX68334.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68334.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX68335.1 - 0.038 14.0 8.7 0.059 13.4 8.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68335.1 - 2.9 8.4 6.1 4.2 7.8 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMP PF05017.14 EAX68337.1 - 0.062 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68338.1 - 0.067 13.1 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX68340.1 - 2.5e-16 59.6 2.4 3.3e-16 59.2 2.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68340.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PSP PF04046.16 EAX68341.1 - 0.07 13.0 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68342.1 - 0.12 13.0 7.9 6.3 7.9 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX68342.1 - 5.3 7.0 8.4 5.6 6.9 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX68343.1 - 1.2e-16 60.5 1.3 1.2e-16 60.5 1.3 3.5 5 0 0 5 5 5 2 Phage tail repeat like HD_2 PF12917.7 EAX68344.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF4108 PF13390.6 EAX68345.1 - 6.7e-43 146.0 2.9 7.4e-43 145.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX68345.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein AAA_22 PF13401.6 EAX68349.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX68349.1 - 6.8e-05 22.9 2.7 0.00012 22.1 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX68349.1 - 9.2e-05 22.2 0.4 0.32 10.7 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX68349.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68349.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68349.1 - 0.0089 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68349.1 - 0.059 12.8 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX68349.1 - 0.069 13.6 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX68349.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX68349.1 - 0.2 11.9 4.1 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX68351.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68351.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX68352.1 - 0.00021 20.9 3.7 0.00037 20.1 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX68352.1 - 0.0058 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX68352.1 - 0.0096 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX68352.1 - 0.033 14.5 2.1 0.072 13.4 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX68352.1 - 0.052 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 T5orf172 PF10544.9 EAX68353.1 - 9.6e-05 22.9 0.2 0.00026 21.5 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX68353.1 - 0.021 14.4 0.5 0.15 11.6 0.2 1.9 2 0 0 2 2 2 0 Legume lectin domain Baculo_ME53 PF06061.11 EAX68353.1 - 0.031 13.5 0.0 0.067 12.4 0.0 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 TMP PF05017.14 EAX68355.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX68355.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX68356.1 - 0.064 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX68359.1 - 0.0041 17.1 7.4 0.0052 16.8 7.4 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX68360.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68360.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_D5 PF03288.16 EAX68361.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68361.1 - 0.071 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PTR PF12789.7 EAX68362.1 - 3.5e-12 46.2 25.7 1e-08 35.1 4.8 5.0 5 0 0 5 5 5 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX68362.1 - 0.0045 17.2 0.3 0.46 10.7 0.0 2.3 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain DUF1910 PF08928.10 EAX68362.1 - 0.014 15.4 0.5 2.8 8.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) IL2 PF00715.17 EAX68362.1 - 0.05 13.5 1.1 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Interleukin 2 MULE PF10551.9 EAX68363.1 - 0.0002 21.7 0.3 0.00068 20.0 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain WRKY PF03106.15 EAX68363.1 - 0.026 14.8 3.2 0.047 13.9 0.8 2.5 1 1 1 2 2 2 0 WRKY DNA -binding domain EpuA PF11772.8 EAX68364.1 - 0.036 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Phage_fiber PF03335.13 EAX68364.1 - 8.1 6.9 24.2 11 6.5 0.5 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX68365.1 - 3.7e-07 29.8 0.1 4.3e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein GatB_Yqey PF02637.18 EAX68365.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 GatB domain DNA_pol_B_2 PF03175.13 EAX68367.1 - 1.8e-25 89.8 5.0 2e-25 89.6 5.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral zinc_ribbon_10 PF10058.9 EAX68368.1 - 1.4 8.7 6.0 3.3 7.5 6.0 1.7 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DNA_pol_B_2 PF03175.13 EAX68369.1 - 6.4e-10 38.5 1.5 1e-09 37.8 1.0 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral MetOD2 PF18548.1 EAX68370.1 - 0.043 13.9 1.1 0.043 13.9 1.1 3.5 2 2 1 3 3 3 0 Metanogen output domain 2 Citrate_bind PF16114.5 EAX68370.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding NurA PF09376.10 EAX68370.1 - 0.45 10.2 7.6 0.13 11.9 3.3 1.8 1 1 1 2 2 2 0 NurA domain CENP-O PF09496.10 EAX68370.1 - 3.5 7.5 10.7 2.4 8.1 5.2 2.2 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component Csm1_N PF18504.1 EAX68370.1 - 4.3 7.7 15.5 2.2 8.7 2.7 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF1935 PF09149.10 EAX68371.1 - 0.0042 17.5 1.3 0.0052 17.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Fucose_iso_C PF02952.17 EAX68371.1 - 0.043 13.5 0.4 0.07 12.8 0.3 1.5 1 1 1 2 2 2 0 L-fucose isomerase, C-terminal domain MlaD PF02470.20 EAX68371.1 - 0.092 13.0 3.5 0.73 10.2 0.8 2.3 1 1 1 2 2 2 0 MlaD protein ETF PF01012.21 EAX68371.1 - 0.1 12.5 4.1 0.12 12.2 4.1 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein domain KH_4 PF13083.6 EAX68371.1 - 0.15 12.0 1.3 1.8 8.5 0.1 2.2 1 1 1 2 2 2 0 KH domain DUF5077 PF16871.5 EAX68371.1 - 0.29 11.0 5.7 0.46 10.4 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) T5orf172 PF10544.9 EAX68372.1 - 0.00076 20.0 0.7 0.0022 18.5 0.2 1.9 2 0 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX68372.1 - 0.043 13.0 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 PSP PF04046.16 EAX68373.1 - 0.075 12.9 1.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68375.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX68377.1 - 6.5e-26 91.4 1.2 7.4e-26 91.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) HNH_3 PF13392.6 EAX68378.1 - 6.6e-05 22.6 0.2 0.00012 21.8 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF1840 PF08895.11 EAX68378.1 - 0.0021 18.4 1.3 0.0021 18.4 1.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1840) DUF4746 PF15928.5 EAX68378.1 - 0.067 12.6 9.1 0.081 12.3 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RabGAP-TBC PF00566.18 EAX68378.1 - 0.53 9.9 2.8 1.3 8.6 0.6 2.1 2 0 0 2 2 2 0 Rab-GTPase-TBC domain DNA_pol_phi PF04931.13 EAX68378.1 - 0.63 8.1 8.9 0.88 7.6 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 EAX68378.1 - 0.72 8.3 4.3 0.96 7.8 4.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Radial_spoke PF04712.12 EAX68378.1 - 1.1 8.1 12.8 0.21 10.5 9.1 1.6 2 0 0 2 2 2 0 Radial spokehead-like protein NOA36 PF06524.12 EAX68378.1 - 1.2 8.4 5.9 1.6 8.0 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_assoc2 PF16624.5 EAX68380.1 - 0.016 16.2 3.3 0.02 15.9 3.1 1.3 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger SLC12 PF03522.15 EAX68380.1 - 0.016 14.2 0.4 0.019 14.0 0.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NEMP PF10225.9 EAX68380.1 - 0.67 9.6 1.5 0.76 9.4 1.5 1.1 1 0 0 1 1 1 0 NEMP family Spo0A_C PF08769.11 EAX68381.1 - 0.061 13.4 0.3 0.14 12.3 0.3 1.7 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PTR PF12789.7 EAX68382.1 - 6.9e-08 32.4 1.8 6.9e-08 32.4 1.8 4.9 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX68382.1 - 0.084 12.5 9.0 1.1 8.8 9.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX68385.1 - 2.8e-34 117.3 0.2 2.8e-34 117.3 0.2 1.8 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX68385.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX68385.1 - 0.62 10.6 6.1 3.5 8.1 1.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PTR PF12789.7 EAX68387.1 - 3.6e-30 103.8 9.0 3.6e-30 103.8 9.0 2.7 4 0 0 4 4 4 1 Phage tail repeat like DUF4108 PF13390.6 EAX68389.1 - 9.1e-53 178.0 7.1 1e-52 177.9 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX68390.1 - 6.7e-19 68.1 10.3 4.2e-18 65.5 10.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Fer4_6 PF12837.7 EAX68390.1 - 0.074 13.2 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DUF5106 PF17127.4 EAX68390.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX68391.1 - 1.7e-16 60.0 2.5 1.7e-16 60.0 2.5 4.5 3 2 2 5 5 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX68391.1 - 0.011 15.4 0.4 0.011 15.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF240 PF03086.14 EAX68391.1 - 0.075 12.9 4.6 1.6 8.7 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF240) PTR PF12789.7 EAX68392.1 - 2.4e-52 174.8 36.4 2.9e-34 116.9 16.1 4.9 3 3 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX68392.1 - 0.051 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX68392.1 - 2.1 7.9 19.1 0.2 11.2 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX68393.1 - 0.16 12.5 1.5 6 7.5 0.1 2.1 1 1 0 1 1 1 0 YmaF family VirE PF05272.11 EAX68394.1 - 0.038 13.7 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Pox_A32 PF04665.12 EAX68394.1 - 0.085 12.3 0.8 0.25 10.8 0.1 2.0 1 1 1 2 2 2 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 EAX68394.1 - 0.09 11.7 0.2 8.1 5.2 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DNA_pol_B_2 PF03175.13 EAX68396.1 - 2.6e-15 56.3 8.8 8.9e-15 54.5 8.8 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX68398.1 - 2.7e-79 266.0 8.7 3.5e-79 265.7 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) YmaF PF12788.7 EAX68399.1 - 0.15 12.6 1.6 6.1 7.5 0.1 2.0 1 1 0 1 1 1 0 YmaF family DUF3839 PF12943.7 EAX68400.1 - 4.1e-26 91.9 3.9 5.8e-26 91.4 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX68400.1 - 0.054 13.8 0.4 0.19 12.0 0.0 2.0 1 1 1 2 2 2 0 PRD domain Pox_D5 PF03288.16 EAX68401.1 - 3.5e-05 24.2 1.9 0.00017 22.0 1.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX68402.1 - 6.5e-50 168.8 5.9 7.1e-50 168.6 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3877 PF12993.7 EAX68404.1 - 0.083 12.8 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) PSP PF04046.16 EAX68405.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68406.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX68407.1 - 5.4e-148 491.0 13.6 6.6e-148 490.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX68407.1 - 0.058 13.9 2.3 0.41 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX68407.1 - 0.31 11.5 3.8 9.3 6.8 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX68408.1 - 3.3e-42 142.9 1.3 4e-42 142.6 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain P22_AR_C PF10548.9 EAX68409.1 - 0.068 13.4 0.1 17 5.7 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain RE_MamI PF09567.10 EAX68409.1 - 0.083 12.5 0.4 0.12 12.1 0.4 1.2 1 0 0 1 1 1 0 MamI restriction endonuclease Caskin-tail PF16632.5 EAX68409.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin TMP PF05017.14 EAX68411.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX68413.1 - 3.8e-05 24.1 2.3 0.00023 21.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX68413.1 - 0.013 14.6 1.0 0.018 14.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Amidase02_C PF12123.8 EAX68414.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX68418.1 - 1.2e-213 710.0 16.5 1.3e-213 709.8 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX68418.1 - 0.02 14.7 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX68418.1 - 0.29 11.1 16.4 0.38 10.7 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF737 PF05300.11 EAX68418.1 - 7.3 6.9 12.3 3.6 7.9 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Pox_A32 PF04665.12 EAX68419.1 - 8.7e-06 25.4 2.2 8.7e-06 25.4 2.2 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68419.1 - 2.6e-05 24.5 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68419.1 - 4e-05 23.4 0.3 0.31 10.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68419.1 - 0.00012 22.1 3.1 0.00027 21.0 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68419.1 - 0.00054 19.8 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68419.1 - 0.0015 18.4 0.7 0.0036 17.1 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68419.1 - 0.0016 18.1 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68419.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX68419.1 - 0.06 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX68419.1 - 0.072 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX68419.1 - 0.072 13.5 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68419.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68419.1 - 0.43 10.9 4.3 9.3 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX68421.1 - 8.9e-39 131.4 28.7 1.1e-32 111.9 13.6 4.8 3 2 2 5 5 5 2 Phage tail repeat like PSP PF04046.16 EAX68422.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68423.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX68424.1 - 0.011 16.1 0.7 0.015 15.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68424.1 - 1.8 7.5 4.0 2 7.4 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68424.1 - 5.2 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX68424.1 - 5.4 7.0 7.2 6 6.9 7.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68425.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX68427.1 - 4.2e-62 208.3 6.8 4.7e-62 208.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX68428.1 - 0.11 12.5 2.1 0.22 11.4 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX68429.1 - 8.5e-17 61.2 3.2 1.5e-16 60.4 3.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68429.1 - 0.047 13.0 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX68430.1 - 5.6e-07 30.0 0.2 1.1e-06 29.1 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Gly-zipper_Omp PF13488.6 EAX68431.1 - 0.005 16.8 9.1 0.008 16.2 9.1 1.3 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX68431.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX68431.1 - 0.88 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX68432.1 - 0.15 12.8 1.8 37 5.6 0.1 3.4 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX68433.1 - 2.4e-157 521.6 15.1 3.1e-157 521.2 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX68433.1 - 0.11 12.0 0.1 0.51 9.8 0.1 2.1 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX68433.1 - 1.1 9.8 7.5 2.5 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4378 PF14309.6 EAX68434.1 - 0.018 15.4 0.1 0.074 13.4 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) La PF05383.17 EAX68434.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 La domain PapD_N PF00345.20 EAX68435.1 - 0.0089 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX68435.1 - 0.067 13.2 0.6 0.096 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PSP PF04046.16 EAX68436.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX68438.1 - 2.2e-11 43.3 1.9 1.2e-10 40.9 1.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX68438.1 - 0.062 12.0 0.5 2.6 6.7 0.4 2.8 2 1 0 2 2 2 0 DNA polymerase family B DUF5106 PF17127.4 EAX68438.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) BRO1 PF03097.18 EAX68439.1 - 0.04 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX68439.1 - 5.6 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat TMP PF05017.14 EAX68440.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX68441.1 - 0.0078 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX68443.1 - 3.5e-05 23.8 0.3 3.5e-05 23.8 0.3 3.2 2 1 0 2 2 2 1 Phage tail repeat like DUF445 PF04286.12 EAX68443.1 - 0.0032 17.4 6.5 0.0036 17.2 5.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX68443.1 - 0.012 16.1 1.0 0.099 13.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF1048 PF06304.11 EAX68443.1 - 0.03 14.8 0.6 0.098 13.1 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF4116 PF13475.6 EAX68443.1 - 0.032 14.0 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2120 PF09893.9 EAX68443.1 - 0.11 12.6 4.3 0.16 12.1 0.5 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) ATP-cone PF03477.16 EAX68443.1 - 1.4 9.5 5.0 8 7.1 0.6 3.1 1 1 2 3 3 3 0 ATP cone domain DUF4795 PF16043.5 EAX68443.1 - 8.3 5.9 18.1 9.1e+02 -0.7 18.0 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Pox_D5 PF03288.16 EAX68444.1 - 9.7e-05 22.8 3.2 0.00055 20.4 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX68444.1 - 0.034 13.2 1.2 0.049 12.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX68445.1 - 5.4e-63 211.2 5.8 6e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX68448.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX68449.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX68450.1 - 1.5e-05 25.0 0.6 1.5e-05 25.0 0.6 2.8 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX68450.1 - 1.1 9.8 3.8 17 6.0 0.1 2.8 2 1 0 2 2 2 0 YmaF family DUF3839 PF12943.7 EAX68451.1 - 1.2e-156 519.3 13.8 1.5e-156 519.0 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX68451.1 - 0.1 12.9 0.9 0.52 10.6 0.2 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit NTP_transf_6 PF06042.11 EAX68451.1 - 0.24 11.2 1.4 0.8 9.5 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX68451.1 - 1.1 9.7 6.1 5.2 7.6 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase P22_AR_C PF10548.9 EAX68452.1 - 0.091 13.0 0.2 23 5.2 0.1 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX68452.1 - 0.12 12.8 0.1 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of Caskin ResIII PF04851.15 EAX68454.1 - 2.2e-05 24.5 0.2 2.8e-05 24.2 0.2 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68454.1 - 0.00035 20.4 0.0 0.00045 20.0 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68454.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68454.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68454.1 - 0.0052 17.1 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68454.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX68454.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX68454.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein IstB_IS21 PF01695.17 EAX68454.1 - 0.092 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX68454.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 EAX68455.1 - 0.00045 20.3 8.3 0.09 12.9 0.4 2.2 2 0 0 2 2 2 2 bZIP transcription factor YabA PF06156.13 EAX68455.1 - 0.00091 19.8 3.1 0.46 11.1 0.8 2.1 2 0 0 2 2 2 2 Initiation control protein YabA Laminin_II PF06009.12 EAX68455.1 - 0.0038 17.3 4.7 0.096 12.7 4.6 2.2 1 1 0 1 1 1 1 Laminin Domain II CCDC-167 PF15188.6 EAX68455.1 - 0.0041 17.4 7.9 0.036 14.4 1.6 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 167 DivIC PF04977.15 EAX68455.1 - 0.0051 16.5 7.7 0.14 11.9 0.5 2.4 2 1 0 2 2 2 2 Septum formation initiator DUF4407 PF14362.6 EAX68455.1 - 0.0085 15.5 0.9 0.0099 15.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) YscO PF07321.12 EAX68455.1 - 0.014 15.4 5.7 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO GIT_CC PF16559.5 EAX68455.1 - 0.017 14.9 5.2 3.1 7.8 0.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF724 PF05266.14 EAX68455.1 - 0.022 14.6 2.8 0.027 14.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 EAX68455.1 - 0.023 15.1 8.8 1.1 9.8 2.3 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF4200 PF13863.6 EAX68455.1 - 0.024 15.0 5.8 0.74 10.2 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 EAX68455.1 - 0.024 14.8 7.2 0.14 12.4 2.0 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 EAX68455.1 - 0.025 14.8 4.8 0.18 12.0 1.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAX68455.1 - 0.027 15.1 1.7 1.1 10.0 0.2 2.1 2 0 0 2 2 2 0 SlyX DASH_Spc34 PF08657.10 EAX68455.1 - 0.028 14.2 3.0 0.072 12.9 3.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 Tektin PF03148.14 EAX68455.1 - 0.031 13.0 3.6 0.084 11.6 3.6 1.6 1 1 0 1 1 1 0 Tektin family Prefoldin PF02996.17 EAX68455.1 - 0.036 14.0 1.9 0.036 14.0 1.9 1.9 2 0 0 2 2 2 0 Prefoldin subunit SIKE PF05769.11 EAX68455.1 - 0.036 14.0 4.1 0.044 13.7 4.1 1.1 1 0 0 1 1 1 0 SIKE family Fungal_TACC PF12709.7 EAX68455.1 - 0.043 14.2 5.8 0.16 12.4 1.4 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins OmpH PF03938.14 EAX68455.1 - 0.052 13.9 2.8 0.068 13.5 2.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vps51 PF08700.11 EAX68455.1 - 0.08 13.0 2.5 6.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Vps51/Vps67 THOC7 PF05615.13 EAX68455.1 - 0.099 12.9 8.3 0.16 12.2 1.6 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 TolA_bind_tri PF16331.5 EAX68455.1 - 0.14 12.2 4.0 0.61 10.2 0.9 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF3450 PF11932.8 EAX68455.1 - 0.15 11.3 6.0 0.46 9.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EAX68455.1 - 0.17 11.9 10.6 0.18 11.8 4.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 EAX68455.1 - 0.18 10.0 6.1 0.058 11.6 1.7 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-H PF05837.12 EAX68455.1 - 0.24 11.8 5.9 3.2 8.2 0.4 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ADIP PF11559.8 EAX68455.1 - 0.29 11.2 6.2 0.59 10.2 1.1 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 EAX68455.1 - 0.36 10.9 8.8 3.4 7.8 0.7 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 EAX68455.1 - 0.38 11.2 6.7 2.2 8.7 0.7 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EAX68455.1 - 0.52 10.6 7.5 0.87 9.8 3.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 EAX68455.1 - 0.75 8.8 6.7 2.8 6.9 6.7 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1192 PF06698.11 EAX68455.1 - 0.78 9.8 6.8 1.8 8.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 EAX68455.1 - 1 9.9 10.5 43 4.6 10.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Swi5 PF07061.11 EAX68455.1 - 2.2 8.4 6.0 3.4 7.8 1.4 2.1 2 0 0 2 2 2 0 Swi5 Spc24 PF08286.11 EAX68455.1 - 2.5 8.4 9.0 6.7 7.0 2.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 XhlA PF10779.9 EAX68455.1 - 3.9 7.7 6.5 7.1 6.9 0.7 2.3 1 1 1 2 2 2 0 Haemolysin XhlA bZIP_2 PF07716.15 EAX68455.1 - 5.3 7.2 10.2 2.5 8.3 0.3 2.7 3 0 0 3 3 3 0 Basic region leucine zipper DUF842 PF05811.13 EAX68456.1 - 2.7e-06 27.1 1.1 4.5e-06 26.4 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) SopA PF13981.6 EAX68456.1 - 0.023 15.1 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 SopA-like central domain YABBY PF04690.13 EAX68456.1 - 0.076 13.6 0.5 0.076 13.6 0.5 2.2 1 1 1 2 2 2 0 YABBY protein ZapB PF06005.12 EAX68456.1 - 0.15 12.5 8.4 52 4.4 8.4 2.9 1 1 0 1 1 1 0 Cell division protein ZapB UPF0449 PF15136.6 EAX68456.1 - 2.2 8.8 6.3 2.8 8.5 0.6 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TMPIT PF07851.13 EAX68456.1 - 8.5 5.5 7.4 1.6 7.9 2.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein DNA_pol_B_2 PF03175.13 EAX68457.1 - 3.3e-08 32.8 1.2 6.7e-08 31.8 0.7 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX68457.1 - 0.071 11.8 1.8 1 8.0 1.8 2.3 1 1 0 1 1 1 0 DNA polymerase family B Pox_A32 PF04665.12 EAX68459.1 - 1.6e-07 31.0 0.6 1e-06 28.4 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX68459.1 - 0.046 13.4 0.1 1.1 8.9 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX68459.1 - 0.073 12.9 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX68459.1 - 0.17 12.0 0.0 0.28 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX68460.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68460.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68460.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68460.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2457 PF10446.9 EAX68461.1 - 8.8 5.4 11.4 12 4.9 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MULE PF10551.9 EAX68462.1 - 2.9e-05 24.4 1.9 3.9e-05 24.0 0.5 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX68462.1 - 0.0044 15.9 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF3839 PF12943.7 EAX68463.1 - 5.1e-28 98.1 6.6 7.5e-28 97.6 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX68463.1 - 0.094 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4108 PF13390.6 EAX68467.1 - 6.3e-62 207.7 5.6 7e-62 207.6 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX68468.1 - 0.027 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX68469.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2939 PF11159.8 EAX68470.1 - 0.015 15.7 0.5 0.017 15.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68470.1 - 2 7.3 3.3 2 7.4 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX68470.1 - 3.6 7.6 7.2 3.8 7.5 7.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68471.1 - 0.0073 16.3 0.2 0.0098 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX68472.1 - 0.0013 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68473.1 - 1.7e-156 518.8 14.8 2e-156 518.6 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX68473.1 - 0.12 11.9 0.1 0.39 10.2 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX68473.1 - 0.16 11.8 1.1 0.63 9.9 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX68473.1 - 0.39 11.0 2.4 1.8 8.9 0.0 2.8 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX68473.1 - 0.53 10.8 7.3 1.8 9.1 0.9 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX68474.1 - 6.2e-22 78.1 9.4 7.9e-21 74.5 9.4 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68474.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Herpes_UL25 PF01499.16 EAX68475.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2939 PF11159.8 EAX68477.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68477.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68477.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX68477.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF659 PF04937.15 EAX68479.1 - 0.015 15.1 0.4 0.09 12.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF 659) Pox_A32 PF04665.12 EAX68480.1 - 1.7e-05 24.4 1.8 1.7e-05 24.4 1.8 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX68480.1 - 2.1e-05 24.3 0.3 0.26 11.0 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX68480.1 - 3.2e-05 24.2 0.2 0.00025 21.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX68480.1 - 0.00036 20.6 4.9 0.00083 19.4 4.7 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68480.1 - 0.00057 19.7 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68480.1 - 0.0027 17.6 1.5 0.0048 16.7 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68480.1 - 0.0028 17.3 3.0 0.0078 15.9 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68480.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3783 PF12646.7 EAX68480.1 - 0.053 13.5 0.9 0.62 10.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) TPK_catalytic PF04263.16 EAX68480.1 - 0.065 13.3 0.7 1 9.4 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX68480.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68480.1 - 0.078 13.4 0.1 0.76 10.2 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68480.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68480.1 - 0.59 10.4 4.9 8.5 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX68480.1 - 3.2 8.5 10.6 0.28 11.8 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 VirE PF05272.11 EAX68482.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E RNA_helicase PF00910.22 EAX68482.1 - 0.08 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX68482.1 - 0.08 11.8 0.2 7.1 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Amidase02_C PF12123.8 EAX68485.1 - 0.0029 17.3 0.0 0.0082 15.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX68486.1 - 1.3e-67 227.0 2.0 1.7e-67 226.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX68487.1 - 2.2e-06 27.3 0.8 2.4e-06 27.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX68487.1 - 0.0027 16.6 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX68487.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX68487.1 - 0.022 14.7 0.7 0.047 13.7 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX68487.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68487.1 - 0.085 12.8 0.2 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX68487.1 - 0.22 11.7 1.8 1.7 8.9 0.1 2.5 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain PRA-PH PF01503.17 EAX68488.1 - 0.32 11.5 2.6 2 8.9 2.8 2.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Amidase02_C PF12123.8 EAX68489.1 - 0.0064 16.2 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX68489.1 - 0.19 11.6 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) MG2 PF01835.19 EAX68491.1 - 6.8e-05 23.2 0.2 0.023 15.1 0.1 2.3 2 0 0 2 2 2 2 MG2 domain Cohesin PF00963.18 EAX68491.1 - 0.0001 22.5 0.5 0.0001 22.5 0.5 1.9 2 1 0 2 2 2 1 Cohesin domain DUF4625 PF15418.6 EAX68491.1 - 0.00013 22.3 0.3 0.013 15.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4625) NPCBM_assoc PF10633.9 EAX68491.1 - 0.0052 17.0 1.8 0.043 14.1 0.2 2.8 3 1 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase ChitinaseA_N PF08329.10 EAX68491.1 - 0.0056 16.3 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Chitinase A, N-terminal domain He_PIG PF05345.12 EAX68491.1 - 0.026 14.7 2.2 0.19 11.9 0.1 2.7 3 0 0 3 3 3 0 Putative Ig domain DUF4469 PF14734.6 EAX68491.1 - 0.03 14.5 0.6 0.51 10.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold bMG6 PF17962.1 EAX68491.1 - 0.073 13.2 0.2 5.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 PKD PF00801.20 EAX68491.1 - 0.087 12.7 0.3 0.31 10.9 0.1 2.1 2 1 0 2 2 2 0 PKD domain Lipocalin PF00061.23 EAX68491.1 - 0.1 12.8 1.5 0.13 12.5 0.2 1.7 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family FAS_N PF17828.1 EAX68492.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX68492.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Pox_A32 PF04665.12 EAX68493.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein Noggin PF05806.12 EAX68494.1 - 0.14 12.0 0.7 0.2 11.5 0.7 1.1 1 0 0 1 1 1 0 Noggin PapD_N PF00345.20 EAX68495.1 - 0.026 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX68496.1 - 0.016 15.6 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX68496.1 - 3.2 8.4 6.3 7.6 7.2 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DNTTIP1_dimer PF18192.1 EAX68497.1 - 0.066 13.6 1.5 0.14 12.5 1.5 1.5 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain GPS2_interact PF15784.5 EAX68500.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68500.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX68501.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Ank_5 PF13857.6 EAX68502.1 - 9.1e-08 32.2 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX68502.1 - 2.2e-07 31.3 0.0 3.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX68502.1 - 1.3e-06 28.6 0.0 9.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX68502.1 - 0.00032 21.2 0.0 0.0023 18.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX68502.1 - 0.017 15.6 0.1 0.093 13.3 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat FAS_N PF17828.1 EAX68503.1 - 0.017 15.1 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX68504.1 - 1.4e-21 76.4 0.1 1.9e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain TMP PF05017.14 EAX68506.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Glyco_hydro_30 PF02055.16 EAX68507.1 - 1.9e-31 109.3 0.2 2.4e-31 109.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX68507.1 - 5.7e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAX68507.1 - 0.0015 18.2 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 PSP PF04046.16 EAX68508.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68509.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat IKKbetaNEMObind PF12179.8 EAX68510.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Pox_A32 PF04665.12 EAX68511.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68511.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68511.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68511.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Phage_fiber PF03335.13 EAX68512.1 - 6.1 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX68513.1 - 4.8e-23 81.8 3.6 6.3e-23 81.4 3.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX68515.1 - 1.9e-42 143.6 0.5 4.2e-42 142.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX68515.1 - 0.042 14.5 0.0 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX68516.1 - 2e-138 459.7 17.9 2.4e-138 459.4 17.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX68516.1 - 0.13 12.7 2.0 0.18 12.3 0.3 1.9 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX68516.1 - 0.19 12.0 6.2 0.35 11.2 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX68516.1 - 0.19 12.2 5.2 1.8 9.1 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX68516.1 - 0.21 11.5 1.7 0.55 10.1 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DDR PF08841.10 EAX68517.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX68518.1 - 0.05 13.6 6.5 0.061 13.3 6.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68518.1 - 1.5 9.3 5.1 1.8 9.0 5.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX68519.1 - 9.8e-116 385.4 7.5 1.1e-115 385.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68519.1 - 0.45 11.0 2.6 1.1 9.7 1.1 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX68520.1 - 0.00066 19.2 3.0 0.00091 18.8 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX68520.1 - 0.018 14.8 0.3 0.16 11.7 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX68520.1 - 0.024 14.2 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX68520.1 - 0.028 14.2 0.2 0.037 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) RNA_helicase PF00910.22 EAX68520.1 - 0.045 14.1 0.6 0.27 11.7 0.1 2.3 1 1 2 3 3 3 0 RNA helicase APG12 PF04110.13 EAX68520.1 - 0.068 13.6 1.9 0.12 12.9 1.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Trypan_PARP PF05887.11 EAX68521.1 - 0.065 13.2 9.2 0.12 12.4 9.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX68522.1 - 1.8e-80 269.9 11.5 2.3e-80 269.5 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX68522.1 - 0.041 14.3 0.5 0.046 14.2 0.5 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX68522.1 - 0.1 13.1 0.4 0.18 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX68525.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68526.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX68528.1 - 7.8e-115 382.4 6.5 8.8e-115 382.3 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX68529.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68532.1 - 2.3e-05 24.8 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX68532.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX68532.1 - 0.057 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3839 PF12943.7 EAX68533.1 - 5.3e-40 137.4 3.9 7.2e-40 137.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MULE PF10551.9 EAX68534.1 - 2.5e-05 24.6 0.0 4.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX68534.1 - 0.053 13.6 3.6 0.098 12.8 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX68534.1 - 0.068 13.9 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain TPR_MLP1_2 PF07926.12 EAX68535.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX68535.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX68535.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4107 PF13389.6 EAX68538.1 - 1.8e-71 239.6 3.4 2.3e-71 239.2 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX68539.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX68539.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX68540.1 - 3.8e-24 84.5 12.9 3.8e-24 84.5 12.9 2.7 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX68540.1 - 0.054 14.0 11.4 0.39 11.3 2.7 3.3 2 1 0 3 3 3 0 YmaF family YvrJ PF12841.7 EAX68542.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Amidase02_C PF12123.8 EAX68545.1 - 0.0073 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68546.1 - 2.2e-25 89.6 4.6 3.2e-25 89.0 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX68546.1 - 0.14 12.6 0.6 0.35 11.3 0.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF2939 PF11159.8 EAX68547.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68547.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2960 PF11173.8 EAX68548.1 - 0.034 14.6 0.3 0.082 13.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) DUF5446 PF17522.2 EAX68549.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PSP PF04046.16 EAX68550.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68551.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX68552.1 - 6.1e-05 23.4 1.9 0.00037 20.9 1.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like KilA-N PF04383.13 EAX68553.1 - 2.8e-34 117.3 0.2 2.8e-34 117.3 0.2 1.8 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX68553.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX68553.1 - 0.62 10.6 6.1 3.5 8.1 1.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DNA_pol_B_2 PF03175.13 EAX68555.1 - 5.1e-22 78.4 9.7 1.9e-21 76.5 9.7 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68555.1 - 0.071 13.1 0.0 0.83 9.7 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor AMPKBI PF04739.15 EAX68556.1 - 2.3 8.6 21.3 7 7.0 0.6 4.1 2 2 1 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain Macoilin PF09726.9 EAX68556.1 - 4.5 5.7 12.3 5.8 5.3 12.3 1.1 1 0 0 1 1 1 0 Macoilin family SHIRT PF18655.1 EAX68556.1 - 9.4 6.9 10.9 0.64 10.6 0.3 3.4 3 1 1 4 4 4 0 SHIRT domain DUF4107 PF13389.6 EAX68557.1 - 4.7e-44 150.4 1.2 5.2e-44 150.3 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68557.1 - 0.079 13.3 0.8 0.093 13.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF1493 PF07377.12 EAX68558.1 - 0.036 14.5 0.7 0.075 13.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX68559.1 - 0.017 15.2 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX68560.1 - 0.01 16.2 0.3 0.013 15.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Transposase_mut PF00872.18 EAX68563.1 - 0.008 15.1 0.3 0.011 14.6 0.3 1.2 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 EAX68563.1 - 0.027 14.9 0.8 0.19 12.2 0.3 2.4 2 0 0 2 2 2 0 MULE transposase domain DUF3839 PF12943.7 EAX68565.1 - 4.9e-07 29.5 1.4 7.7e-07 28.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX68566.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX68566.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX68566.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX68566.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX68566.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2486 PF10667.9 EAX68567.1 - 0.34 11.1 30.5 0.23 11.7 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DUF3839 PF12943.7 EAX68568.1 - 2.7e-120 400.3 12.1 3.4e-120 400.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68568.1 - 0.063 13.7 1.5 11 6.6 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX68568.1 - 0.065 12.7 0.1 0.27 10.7 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX68568.1 - 0.29 11.0 2.1 0.64 9.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase FAS_N PF17828.1 EAX68569.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX68570.1 - 3e-27 94.7 0.4 7.6e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX68571.1 - 5e-125 415.8 6.1 5.7e-125 415.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX68571.1 - 0.17 12.2 1.1 0.51 10.7 1.1 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Amidase02_C PF12123.8 EAX68572.1 - 0.0036 17.0 0.1 0.0097 15.6 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68574.1 - 3.4e-80 269.0 11.0 4.4e-80 268.6 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX68574.1 - 0.023 14.7 0.7 3.6 7.6 0.2 2.3 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 EAX68574.1 - 0.025 15.0 0.5 0.032 14.7 0.5 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX68574.1 - 0.091 12.3 0.3 0.49 9.9 0.0 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX68574.1 - 0.092 13.3 0.6 0.15 12.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 EAX68574.1 - 0.096 13.0 1.1 0.22 11.8 1.1 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 NTP_transf_6 PF06042.11 EAX68574.1 - 0.34 10.8 2.4 0.8 9.5 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX68575.1 - 0.062 13.9 4.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX68577.1 - 0.0075 15.9 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX68577.1 - 0.15 12.0 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX68581.1 - 8.9e-08 31.9 0.8 1.1e-07 31.6 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68581.1 - 0.0031 17.2 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68581.1 - 0.045 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68581.1 - 0.091 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX68583.1 - 3.5e-42 142.8 0.8 5.7e-42 142.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX68584.1 - 1.1e-53 179.2 34.6 1.2e-34 118.1 17.2 4.7 2 2 1 4 4 4 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX68584.1 - 0.66 10.3 5.6 18 5.7 0.1 3.8 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF5327 PF17261.2 EAX68584.1 - 2.9 8.7 7.3 1 10.1 0.9 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5327) KilA-N PF04383.13 EAX68585.1 - 1e-33 115.5 0.8 1.7e-33 114.8 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX68586.1 - 6.9e-07 29.7 0.3 1.4e-06 28.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pex14_N PF04695.13 EAX68587.1 - 2.1 9.0 8.3 2.4 8.8 8.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTR PF12789.7 EAX68589.1 - 0.0067 16.5 0.3 0.0067 16.5 0.3 3.1 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX68589.1 - 0.065 12.0 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX68589.1 - 0.48 10.0 3.2 1.9 8.0 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX68589.1 - 6.7 7.2 15.3 3.3 8.1 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat KilA-N PF04383.13 EAX68590.1 - 2.2e-45 153.1 0.1 2.2e-45 153.1 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX68590.1 - 0.014 16.0 0.1 0.044 14.4 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Parathyroid PF01279.17 EAX68591.1 - 0.018 15.7 0.0 0.039 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF5401 PF17380.2 EAX68592.1 - 0.047 11.8 48.5 0.069 11.2 48.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MAP7 PF05672.11 EAX68592.1 - 0.69 9.6 98.8 2.2 8.0 58.8 2.2 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Mitofilin PF09731.9 EAX68592.1 - 2.3 7.0 53.5 3.9 6.2 53.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF572 PF04502.13 EAX68592.1 - 5 6.7 43.1 9.1 5.8 43.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 EAX68592.1 - 6.4 5.3 23.8 8.3 4.9 23.8 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 EAX68592.1 - 7 5.9 55.1 10 5.4 55.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_B_2 PF03175.13 EAX68593.1 - 9.3e-12 44.5 0.5 1.9e-11 43.5 0.5 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68593.1 - 0.024 13.9 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Pox_D5 PF03288.16 EAX68594.1 - 4.6e-05 23.8 3.1 0.00034 21.0 3.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX68595.1 - 1.7e-60 203.1 9.5 1.9e-60 202.9 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68598.1 - 1.5e-05 25.4 0.4 2.1e-05 24.9 0.4 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68598.1 - 0.044 14.4 0.1 0.06 14.0 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68598.1 - 0.079 12.9 0.3 0.12 12.3 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX68599.1 - 2.2e-64 215.7 6.2 2.5e-64 215.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX68599.1 - 0.1 12.8 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3417 PF11897.8 EAX68600.1 - 0.11 13.0 0.4 0.13 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) SH3BGR PF04908.15 EAX68600.1 - 0.2 11.8 3.5 0.24 11.6 3.3 1.3 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2897 PF11446.8 EAX68600.1 - 0.55 10.2 3.2 0.95 9.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX68602.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AbfS_sensor PF18225.1 EAX68603.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain DUF4108 PF13390.6 EAX68605.1 - 2.4e-50 170.2 6.6 2.7e-50 170.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX68606.1 - 0.032 14.5 1.7 0.043 14.1 1.7 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX68606.1 - 0.073 13.0 2.1 0.14 12.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX68606.1 - 0.11 12.9 0.4 0.13 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX68607.1 - 3e-60 202.3 8.1 3.4e-60 202.1 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX68608.1 - 0.03 14.6 2.8 0.03 14.6 2.8 1.1 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX68608.1 - 0.04 13.8 1.6 0.046 13.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX68609.1 - 5.6e-08 32.5 0.9 6.3e-08 32.4 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68609.1 - 0.0053 16.4 0.1 0.0055 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX68609.1 - 0.061 13.3 0.4 0.57 10.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX68609.1 - 0.073 12.8 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX68610.1 - 3.3e-25 89.0 4.6 5.2e-25 88.3 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX68610.1 - 0.043 14.1 0.6 0.17 12.2 0.1 2.1 1 1 1 2 2 2 0 PRD domain DNA_pol_B_2 PF03175.13 EAX68611.1 - 3.6e-23 82.2 4.8 4.6e-23 81.8 4.8 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX68612.1 - 0.028 14.8 0.4 0.038 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX68612.1 - 2.6 8.7 6.3 6.1 7.5 6.3 1.7 1 1 0 1 1 1 0 Homeodomain-like domain KilA-N PF04383.13 EAX68613.1 - 1.9e-34 117.9 0.2 1.9e-34 117.9 0.2 1.7 2 1 1 3 3 3 1 KilA-N domain Parathyroid PF01279.17 EAX68613.1 - 0.02 15.5 0.0 0.047 14.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX68613.1 - 0.45 10.5 4.2 1.5 8.8 0.5 2.2 2 0 0 2 2 2 0 Tumour suppressor protein DUF4106 PF13388.6 EAX68615.1 - 1e-113 380.8 8.8 1e-113 380.8 8.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX68615.1 - 0.56 8.7 3.7 0.75 8.3 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_pol_B_2 PF03175.13 EAX68617.1 - 9e-12 44.6 0.5 1.9e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68617.1 - 0.028 13.7 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX68617.1 - 0.12 12.4 0.3 9.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type VSP PF03302.13 EAX68618.1 - 0.00016 20.7 0.6 0.0002 20.3 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EAX68618.1 - 0.00058 20.0 1.6 0.00076 19.6 1.6 1.2 1 0 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 EAX68618.1 - 0.0026 18.2 1.4 0.0042 17.6 1.4 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 ECSCR PF15820.5 EAX68618.1 - 0.0035 17.2 0.2 0.0052 16.6 0.2 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator SKG6 PF08693.10 EAX68618.1 - 0.0096 15.3 7.3 0.015 14.7 7.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 EAX68618.1 - 0.014 15.7 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 EAX68618.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 EAX68618.1 - 0.017 14.7 0.8 0.024 14.2 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) YajC PF02699.15 EAX68618.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.6 EAX68618.1 - 0.022 15.6 1.1 0.048 14.6 1.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 EAX68618.1 - 0.026 14.8 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A DUF4448 PF14610.6 EAX68618.1 - 0.035 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.6 EAX68618.1 - 0.036 12.9 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 EAX68618.1 - 0.037 13.9 0.3 0.039 13.9 0.3 1.2 1 0 0 1 1 1 0 Rifin DUF4690 PF15756.5 EAX68618.1 - 0.045 14.4 0.1 0.068 13.8 0.1 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FeoB_associated PF12669.7 EAX68618.1 - 0.085 13.3 4.5 0.18 12.3 4.5 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Syndecan PF01034.20 EAX68618.1 - 0.65 10.0 7.7 0.54 10.2 5.9 1.8 1 1 1 2 2 2 0 Syndecan domain DUF3139 PF11337.8 EAX68618.1 - 1.2 9.8 6.0 4 8.2 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) DUF2939 PF11159.8 EAX68619.1 - 0.025 15.0 0.5 0.031 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68619.1 - 1.3 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX68619.1 - 1.4 8.9 5.5 1.5 8.8 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX68623.1 - 0.0077 16.2 0.1 0.009 16.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta TMP PF05017.14 EAX68624.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68625.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ResIII PF04851.15 EAX68628.1 - 3.3e-05 23.9 1.7 5.9e-05 23.1 1.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68628.1 - 0.00028 20.7 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68628.1 - 0.00039 20.7 0.0 0.00066 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68628.1 - 0.00073 19.4 0.7 0.0018 18.1 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68628.1 - 0.0061 16.9 0.0 0.008 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68628.1 - 0.038 13.4 0.1 0.081 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX68628.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX68628.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68628.1 - 0.22 11.2 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX68628.1 - 0.31 11.3 4.8 4.2 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX68628.1 - 0.69 10.4 4.3 0.29 11.6 1.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 BUD22 PF09073.10 EAX68629.1 - 3.1 7.0 12.4 3.4 6.9 12.4 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_B_2 PF03175.13 EAX68630.1 - 8.5e-23 80.9 3.4 1e-22 80.6 3.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68630.1 - 0.097 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX68631.1 - 2.4e-10 39.9 2.2 1e-09 37.8 2.1 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68631.1 - 0.11 12.4 0.0 0.83 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX68631.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 T5orf172 PF10544.9 EAX68632.1 - 2.8e-06 27.8 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX68632.1 - 0.011 15.6 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX68632.1 - 0.017 14.7 1.1 0.16 11.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAX68634.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX68635.1 - 1.1e-09 37.7 0.6 1.1e-09 37.7 0.6 2.0 2 1 1 3 3 3 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX68635.1 - 0.088 12.4 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 Isy1-like splicing family DUF3839 PF12943.7 EAX68636.1 - 3.1e-113 377.2 9.5 4.4e-113 376.7 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX68636.1 - 0.0036 17.8 0.1 0.015 15.8 0.1 2.2 2 0 0 2 2 2 1 T5orf172 domain Fez1 PF06818.15 EAX68636.1 - 0.0093 16.4 0.2 0.016 15.7 0.2 1.3 1 0 0 1 1 1 1 Fez1 KELK PF15796.5 EAX68636.1 - 0.045 14.2 1.0 3.1 8.3 0.0 2.8 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Lectin_legB PF00139.19 EAX68636.1 - 0.12 11.9 1.0 5.9 6.3 0.2 2.2 2 0 0 2 2 2 0 Legume lectin domain DNA_pol_B_2 PF03175.13 EAX68637.1 - 4e-10 39.2 0.1 4e-10 39.2 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral CTNNBL PF08216.11 EAX68637.1 - 0.12 12.6 0.1 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear TFCD_C PF12612.8 EAX68637.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal JMY PF15871.5 EAX68639.1 - 0.0054 16.1 0.5 0.0072 15.7 0.5 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX68639.1 - 0.13 12.3 1.1 0.27 11.3 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX68639.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain PapD_N PF00345.20 EAX68641.1 - 0.023 14.6 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX68641.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX68642.1 - 2.9e-17 62.7 2.7 3.3e-17 62.5 2.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Trypan_PARP PF05887.11 EAX68645.1 - 0.04 13.9 8.0 0.062 13.3 8.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68645.1 - 3.3 8.2 5.0 4.7 7.7 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR PF12789.7 EAX68646.1 - 1.1e-10 41.4 2.8 1.1e-10 41.4 2.8 4.2 2 2 2 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX68646.1 - 0.052 13.3 1.3 0.13 12.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Transposase_24 PF03004.14 EAX68646.1 - 1.1 9.4 6.3 13 5.9 5.8 2.5 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF3781 PF12636.7 EAX68647.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) UDPGP PF01704.18 EAX68648.1 - 9.3e-91 304.5 0.4 1e-90 304.4 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pox_A32 PF04665.12 EAX68649.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX68649.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68649.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68649.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68649.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68649.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68649.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX68649.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX68649.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX68649.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68649.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68649.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) HCBP_related PF06594.11 EAX68650.1 - 0.11 12.4 0.0 1.4e+02 2.5 0.0 3.7 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain Chordopox_A30L PF06015.12 EAX68650.1 - 0.67 9.8 5.4 11 5.9 0.3 2.4 1 1 2 3 3 3 0 Chordopoxvirus A30L protein T5orf172 PF10544.9 EAX68651.1 - 1.1e-06 29.1 0.3 2.2e-06 28.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX68652.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX68653.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) KilA-N PF04383.13 EAX68654.1 - 0.00082 19.2 0.1 0.0015 18.3 0.1 1.5 1 1 0 1 1 1 1 KilA-N domain AAA_11 PF13086.6 EAX68655.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX68655.1 - 0.076 12.6 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX68655.1 - 0.076 13.3 0.2 0.12 12.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX68655.1 - 0.18 11.3 0.0 0.2 11.1 0.0 1.3 1 1 0 1 1 1 0 PhoH-like protein DUF2897 PF11446.8 EAX68656.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX68657.1 - 8.6e-06 26.2 1.8 4.9e-05 23.7 1.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68657.1 - 0.007 17.0 0.1 0.015 15.9 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68657.1 - 0.017 15.1 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4107 PF13389.6 EAX68658.1 - 7e-69 231.1 1.6 9.2e-69 230.7 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68658.1 - 0.1 12.9 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX68660.1 - 1.1e-17 64.0 3.0 1.3e-17 63.9 3.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX68662.1 - 0.066 13.7 0.4 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX68663.1 - 2.4e-17 62.8 0.7 5.2e-17 61.7 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF1493 PF07377.12 EAX68664.1 - 0.018 15.5 0.8 0.034 14.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2897 PF11446.8 EAX68666.1 - 1.2 9.1 4.2 2.2 8.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Trypan_PARP PF05887.11 EAX68667.1 - 0.04 13.9 8.7 0.062 13.3 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX68668.1 - 5.1e-09 36.0 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX68668.1 - 0.089 12.2 0.6 0.1 12.1 0.6 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX68668.1 - 0.11 12.0 0.6 0.22 10.9 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Trypan_PARP PF05887.11 EAX68669.1 - 0.12 12.3 9.1 0.14 12.1 9.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68669.1 - 0.81 10.1 5.5 0.93 9.9 5.5 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX68670.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68670.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX68672.1 - 9.1e-58 194.2 9.1 1e-57 194.1 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PcfK PF14058.6 EAX68673.1 - 0.24 11.7 8.0 0.39 11.0 8.0 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF3839 PF12943.7 EAX68674.1 - 1.4e-158 525.7 14.6 1.6e-158 525.5 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68674.1 - 1.3 9.5 8.3 2 8.9 0.7 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX68675.1 - 5e-07 29.3 8.8 9.3e-07 28.4 8.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) PTR PF12789.7 EAX68676.1 - 2e-63 210.3 41.7 8.8e-33 112.2 17.4 5.5 4 2 3 7 7 7 3 Phage tail repeat like DUF4795 PF16043.5 EAX68676.1 - 0.0022 17.6 7.0 0.045 13.4 5.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX68676.1 - 0.87 10.0 5.1 18 5.7 0.2 3.9 3 1 2 5 5 5 0 TFIIH p62 subunit, N-terminal domain TMP PF05017.14 EAX68677.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Mito_fiss_reg PF05308.11 EAX68679.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX68679.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX68681.1 - 0.015 15.8 0.9 0.027 14.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2897 PF11446.8 EAX68682.1 - 0.17 11.8 3.2 0.23 11.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX68683.1 - 1.1e-61 206.9 6.4 1.3e-61 206.8 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68684.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68684.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68684.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain PapD_N PF00345.20 EAX68685.1 - 0.065 13.1 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX68685.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX68686.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX68686.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Noggin PF05806.12 EAX68689.1 - 0.28 11.1 1.4 0.4 10.6 1.4 1.1 1 0 0 1 1 1 0 Noggin Pox_A32 PF04665.12 EAX68690.1 - 2.1e-07 30.7 0.6 1.3e-06 28.1 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX68690.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EAX68690.1 - 0.04 13.5 0.1 0.85 9.2 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX68690.1 - 0.046 13.6 0.2 0.068 13.0 0.2 1.3 1 0 0 1 1 1 0 Thymidine kinase PBAN PF05874.11 EAX68690.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) HECT PF00632.25 EAX68691.1 - 3.9e-21 75.9 0.3 7.4e-20 71.6 0.6 1.9 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF3839 PF12943.7 EAX68692.1 - 1.8e-151 502.4 13.3 2.1e-151 502.2 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX68692.1 - 0.046 14.0 5.4 0.26 11.6 0.1 3.2 2 2 0 2 2 2 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX68692.1 - 0.074 12.9 1.1 0.21 11.4 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX68692.1 - 0.43 11.1 7.3 1.5 9.3 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UPF0239 PF06783.11 EAX68693.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF2939 PF11159.8 EAX68694.1 - 0.017 15.6 0.5 0.022 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68694.1 - 1.4 8.9 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GPS2_interact PF15784.5 EAX68695.1 - 0.036 14.5 0.5 0.049 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DNA_pol_B_2 PF03175.13 EAX68696.1 - 3.8e-23 82.1 3.9 6.5e-23 81.3 3.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68696.1 - 0.065 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein FliJ PF02050.16 EAX68698.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein SL4P PF17618.2 EAX68699.1 - 0.11 12.5 2.4 5.6 7.1 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein IKKbetaNEMObind PF12179.8 EAX68700.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain KilA-N PF04383.13 EAX68701.1 - 1e-23 83.3 0.3 2.8e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain PhaP_Bmeg PF09602.10 EAX68702.1 - 0.052 13.5 0.1 0.33 10.9 0.1 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) GED PF02212.18 EAX68703.1 - 0.038 14.1 2.5 0.064 13.4 2.5 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain RskA PF10099.9 EAX68703.1 - 0.062 13.6 0.4 0.065 13.5 0.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 EAX68703.1 - 2.6 8.0 4.2 2.6 8.0 4.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HTH_32 PF13565.6 EAX68703.1 - 2.9 8.6 5.2 13 6.5 5.2 1.9 1 1 0 1 1 1 0 Homeodomain-like domain PSP PF04046.16 EAX68704.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68705.1 - 0.046 14.3 4.9 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX68706.1 - 0.0092 15.7 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase AAA_22 PF13401.6 EAX68708.1 - 3e-05 24.3 0.2 0.00024 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68708.1 - 3.8e-05 23.5 0.5 0.42 10.3 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX68708.1 - 6.8e-05 22.4 2.2 6.8e-05 22.4 2.2 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein DEAD PF00270.29 EAX68708.1 - 0.00055 19.7 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX68708.1 - 0.0008 19.4 6.4 0.00082 19.4 4.7 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX68708.1 - 0.005 16.5 3.3 0.014 15.1 0.2 2.6 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX68708.1 - 0.0058 16.4 0.9 0.0058 16.4 0.9 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX68708.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX68708.1 - 0.068 12.7 0.0 0.23 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX68708.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX68708.1 - 0.11 12.6 1.7 2.1 8.4 1.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA PF00004.29 EAX68708.1 - 0.11 12.9 0.9 0.73 10.3 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX68708.1 - 2.5 8.8 13.1 0.16 12.7 3.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 T5orf172 PF10544.9 EAX68712.1 - 0.00062 20.3 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX68712.1 - 0.046 13.3 0.7 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain PSP PF04046.16 EAX68714.1 - 0.078 12.9 0.6 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68715.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1031 PF06275.11 EAX68716.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX68716.1 - 0.041 13.9 0.4 0.19 11.8 0.2 1.9 1 1 1 2 2 2 0 Annexin HARE-HTH PF05066.13 EAX68716.1 - 0.1 13.0 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain ArsC PF03960.15 EAX68717.1 - 0.048 13.7 0.8 0.073 13.1 0.8 1.5 1 1 0 1 1 1 0 ArsC family PSP PF04046.16 EAX68718.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68719.1 - 0.026 15.0 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX68720.1 - 3.8e-153 507.9 11.8 4.4e-153 507.6 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX68720.1 - 0.014 15.1 1.9 0.033 13.8 0.6 2.3 1 1 0 2 2 2 0 Proteasome activator pa28 beta subunit Fez1 PF06818.15 EAX68720.1 - 0.07 13.6 1.4 0.18 12.2 0.2 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX68720.1 - 0.22 12.0 4.5 3.2 8.3 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX68720.1 - 0.38 11.1 3.7 0.67 10.3 2.0 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX68720.1 - 0.83 10.2 5.0 1.5 9.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4106 PF13388.6 EAX68721.1 - 2e-212 705.9 20.3 2.3e-212 705.7 20.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Dicty_REP PF05086.12 EAX68721.1 - 1.7 6.5 4.7 2.3 6.1 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EAX68721.1 - 3.9 6.0 5.8 6.1 5.4 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup KilA-N PF04383.13 EAX68722.1 - 1.5e-30 105.3 1.0 2.5e-30 104.6 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX68722.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DNA_pol_B_2 PF03175.13 EAX68724.1 - 7.4e-23 81.1 4.1 9.4e-23 80.8 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX68725.1 - 3.2e-130 432.8 7.5 3.6e-130 432.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68725.1 - 0.21 12.0 1.9 1.1 9.8 0.5 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spo12 PF05032.12 EAX68727.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family CBP4 PF07960.11 EAX68728.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 CBP4 XPC-binding PF09280.11 EAX68728.1 - 0.072 12.8 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 XPC-binding domain DUF3839 PF12943.7 EAX68729.1 - 2.8e-118 393.7 7.8 3.3e-118 393.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Chal_sti_synt_N PF00195.19 EAX68730.1 - 0.063 12.7 0.2 0.1 12.0 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain T5orf172 PF10544.9 EAX68731.1 - 2e-06 28.3 0.3 4.3e-06 27.2 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain TMP PF05017.14 EAX68734.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX68735.1 - 0.021 15.3 0.8 0.037 14.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Peptidase_S64 PF08192.11 EAX68736.1 - 0.013 14.1 0.0 0.015 13.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3839 PF12943.7 EAX68737.1 - 1.6e-79 266.8 9.2 2e-79 266.5 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX68737.1 - 0.079 12.8 1.0 0.26 11.1 0.9 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase KilA-N PF04383.13 EAX68738.1 - 3.7e-33 113.7 0.1 5.1e-33 113.3 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX68738.1 - 0.11 12.5 0.4 0.14 12.1 0.4 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon T5orf172 PF10544.9 EAX68739.1 - 4.3e-07 30.4 0.2 8e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain T5orf172 PF10544.9 EAX68740.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PBP_sp32 PF07222.12 EAX68741.1 - 1.1 8.7 7.7 1.6 8.2 7.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PcfK PF14058.6 EAX68741.1 - 2.5 8.4 14.9 3.8 7.8 14.9 1.4 1 1 0 1 1 1 0 PcfK-like protein ResIII PF04851.15 EAX68742.1 - 2.2e-05 24.5 0.2 2.8e-05 24.2 0.2 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68742.1 - 0.00035 20.4 0.0 0.00045 20.0 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68742.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68742.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68742.1 - 0.0052 17.1 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68742.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX68742.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX68742.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein IstB_IS21 PF01695.17 EAX68742.1 - 0.092 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX68742.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1493 PF07377.12 EAX68743.1 - 0.046 14.2 0.2 0.089 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX68745.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68745.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX68745.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX68745.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX68745.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX68745.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX68745.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX68746.1 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX68748.1 - 1.1e-157 522.7 14.0 1.5e-157 522.3 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX68748.1 - 0.019 15.5 1.7 0.098 13.1 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX68748.1 - 0.6 10.6 6.8 2.2 8.8 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX68749.1 - 0.02 15.3 0.7 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68749.1 - 1.6 7.7 4.0 1.7 7.6 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68749.1 - 3.8 8.2 6.6 8.4 7.1 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX68749.1 - 4.1 7.4 7.6 4.4 7.3 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX68750.1 - 6.4e-121 402.3 11.2 8.3e-121 402.0 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68750.1 - 0.11 13.0 1.5 0.99 9.9 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX68750.1 - 0.11 13.1 0.8 0.22 12.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX68750.1 - 0.18 11.6 1.2 0.67 9.8 0.2 1.9 1 1 0 2 2 2 0 Nucleotidyltransferase DUF1493 PF07377.12 EAX68751.1 - 0.035 14.6 0.2 0.051 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) WRKY PF03106.15 EAX68752.1 - 1.6 9.0 8.1 0.15 12.3 0.7 2.7 2 2 1 3 3 3 0 WRKY DNA -binding domain T5orf172 PF10544.9 EAX68754.1 - 1e-06 29.2 0.3 2.7e-06 27.9 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain DUF4106 PF13388.6 EAX68755.1 - 9.5e-168 558.8 22.3 1.5e-167 558.1 22.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX68755.1 - 0.0059 16.9 0.1 0.4 11.0 0.1 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated Trypan_PARP PF05887.11 EAX68756.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX68757.1 - 0.068 13.1 0.9 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68758.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX68759.1 - 1.3e-18 66.9 1.3 1.9e-18 66.3 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX68759.1 - 0.014 16.0 0.0 0.028 15.0 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family PapD_N PF00345.20 EAX68764.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX68764.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF5365 PF17326.2 EAX68766.1 - 0.0077 16.6 0.2 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5365) PWI PF01480.17 EAX68766.1 - 0.027 14.8 0.3 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain Pox_D5 PF03288.16 EAX68767.1 - 2e-05 25.0 2.6 0.00011 22.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68767.1 - 0.048 14.3 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX68768.1 - 7.1e-63 210.8 4.7 9.2e-63 210.4 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX68769.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68769.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX68769.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX68770.1 - 0.0088 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX68772.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX68773.1 - 6.4e-23 80.7 0.3 1.1e-22 80.0 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX68773.1 - 0.045 13.7 0.9 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMP PF05017.14 EAX68774.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX68776.1 - 0.0048 16.9 0.1 0.0051 16.8 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX68777.1 - 1.4e-146 486.4 11.8 1.7e-146 486.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68777.1 - 0.085 13.3 3.8 2.2 8.8 0.1 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX68778.1 - 3.3e-07 30.0 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68778.1 - 0.0045 16.7 0.1 0.006 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX68778.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX68778.1 - 0.063 13.0 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX68778.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX68778.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX68778.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX68779.1 - 9.9e-08 31.9 0.9 9.9e-08 31.9 0.9 3.0 4 0 0 4 4 4 1 Phage tail repeat like EDR1 PF14381.6 EAX68779.1 - 0.019 14.7 2.4 0.56 9.9 0.8 2.2 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Phage_tail_X PF05489.12 EAX68779.1 - 0.083 12.6 0.0 7.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage Tail Protein X LIN52 PF10044.9 EAX68779.1 - 1.4 9.6 5.8 20 6.0 0.8 2.5 1 1 1 2 2 2 0 Retinal tissue protein DUF4378 PF14309.6 EAX68780.1 - 0.023 15.1 0.0 0.052 13.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) DUF1493 PF07377.12 EAX68781.1 - 0.027 15.0 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX68781.1 - 0.27 11.3 2.1 9.1 6.4 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DNA_pol_B_2 PF03175.13 EAX68782.1 - 4.2e-23 82.0 3.3 5.4e-23 81.6 3.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68782.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX68783.1 - 2.8e-23 81.7 8.9 2.8e-23 81.7 8.9 3.9 2 2 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX68783.1 - 0.036 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX68783.1 - 0.54 10.2 7.2 1.4 8.8 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX68784.1 - 0.024 15.1 0.7 0.045 14.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX68785.1 - 8.8e-42 143.0 7.8 6.9e-40 136.8 7.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX68786.1 - 1.4e-155 515.9 15.5 1.5e-155 515.7 15.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX68786.1 - 0.13 12.1 1.1 0.49 10.2 0.2 2.0 1 1 0 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX68786.1 - 0.62 10.6 6.9 1.7 9.2 0.9 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX68788.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FAS_N PF17828.1 EAX68789.1 - 0.008 16.2 0.1 0.0093 16.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Btz PF09405.10 EAX68791.1 - 0.43 10.8 8.2 0.55 10.5 8.2 1.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PBP_sp32 PF07222.12 EAX68791.1 - 0.62 9.5 6.5 0.66 9.4 6.5 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3464 PF11947.8 EAX68791.1 - 0.87 9.3 4.0 0.82 9.4 4.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX68792.1 - 8.7e-54 181.3 7.7 9.7e-54 181.2 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68793.1 - 6.9e-06 26.5 0.6 9.6e-06 26.0 0.6 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68793.1 - 0.01 16.5 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68793.1 - 0.023 14.7 0.2 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain T5orf172 PF10544.9 EAX68794.1 - 2.5e-07 31.2 0.2 4.7e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX68795.1 - 6.5e-07 29.1 0.8 7.8e-07 28.8 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX68796.1 - 6.4e-25 87.9 6.6 3.5e-24 85.5 6.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68796.1 - 0.066 13.2 0.0 0.81 9.7 0.0 2.7 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX68796.1 - 0.12 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX68798.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX68798.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DDR PF08841.10 EAX68800.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX68800.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX68801.1 - 0.45 10.5 7.2 0.53 10.3 7.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68801.1 - 7.3 7.0 6.5 8.6 6.8 6.5 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4106 PF13388.6 EAX68802.1 - 1.2e-95 321.3 5.3 1.2e-95 321.3 5.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX68802.1 - 0.1 11.2 2.8 0.14 10.8 2.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4106 PF13388.6 EAX68803.1 - 1.3e-34 120.2 46.8 1.6e-33 116.6 46.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) PT PF04886.12 EAX68803.1 - 1.5 8.4 54.5 1.8e+04 -14.5 54.5 3.2 1 1 0 1 1 1 0 PT repeat DDE_Tnp_4 PF13359.6 EAX68808.1 - 1.9e-36 125.1 0.0 2.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX68808.1 - 1.8e-07 31.0 0.7 3.2e-06 26.9 0.7 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX68808.1 - 4.9e-05 23.0 0.8 0.0014 18.3 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 EAX68808.1 - 0.13 12.6 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain DUF3839 PF12943.7 EAX68809.1 - 1.6e-102 342.1 8.4 1.8e-102 341.9 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Mito_fiss_reg PF05308.11 EAX68810.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX68810.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MULE PF10551.9 EAX68811.1 - 8.4e-10 38.9 0.2 2e-09 37.7 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX68811.1 - 0.011 15.4 0.4 0.08 12.6 0.1 1.9 1 1 1 2 2 2 0 Transposase Transposase_mut PF00872.18 EAX68811.1 - 0.022 13.6 0.2 0.032 13.1 0.2 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Vta1 PF04652.16 EAX68811.1 - 0.027 14.4 0.3 0.044 13.8 0.3 1.2 1 0 0 1 1 1 0 Vta1 like AAA_22 PF13401.6 EAX68813.1 - 1.8e-05 25.1 0.2 0.00013 22.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68813.1 - 1.9e-05 24.4 0.3 0.31 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX68813.1 - 0.00011 22.2 3.4 0.00021 21.3 3.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68813.1 - 0.00039 20.2 0.1 0.00064 19.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX68813.1 - 0.00098 19.0 0.6 0.0027 17.5 0.6 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX68813.1 - 0.0014 18.2 1.5 0.0014 18.2 1.5 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX68813.1 - 0.0097 16.3 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX68813.1 - 0.02 14.6 0.3 0.17 11.5 0.1 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 EAX68813.1 - 0.036 13.6 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX68813.1 - 0.055 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX68813.1 - 0.055 13.9 0.1 0.45 10.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX68813.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX68813.1 - 0.087 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX68813.1 - 0.44 10.8 5.1 7.1 7.0 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Trypan_PARP PF05887.11 EAX68814.1 - 0.021 14.8 10.0 0.03 14.3 10.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX68815.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68815.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX68816.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX68817.1 - 7.3e-32 109.2 8.0 7.3e-32 109.2 8.0 2.9 4 0 0 4 4 4 1 Phage tail repeat like DUF4106 PF13388.6 EAX68819.1 - 2.4e-111 373.0 6.2 2.4e-111 373.0 6.2 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX68819.1 - 0.0016 18.7 4.7 0.02 15.2 0.3 3.3 3 1 0 3 3 3 1 Kidney androgen-regulated SH3_7 PF12914.7 EAX68820.1 - 0.0033 17.6 0.4 8.9 6.6 0.2 3.7 3 1 0 3 3 3 3 SH3 domain of SH3b2 type Pox_A32 PF04665.12 EAX68821.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68821.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68821.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68821.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4106 PF13388.6 EAX68822.1 - 5.1e-159 530.0 48.5 3.8e-152 507.4 16.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) VP4_2 PF08935.10 EAX68822.1 - 0.12 13.0 0.7 0.25 11.9 0.7 1.5 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX68822.1 - 0.52 10.7 7.0 6.7 7.2 0.4 3.3 3 0 0 3 3 3 0 WYL domain PSP PF04046.16 EAX68823.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX68824.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX68824.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4107 PF13389.6 EAX68825.1 - 5.7e-35 120.9 3.4 6.9e-35 120.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX68825.1 - 0.028 12.9 0.9 0.027 12.9 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX68827.1 - 1.3e-53 178.9 36.7 7e-35 118.9 16.2 4.2 3 2 1 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX68827.1 - 0.0034 17.0 9.1 0.08 12.5 3.9 3.1 2 2 0 2 2 2 2 Domain of unknown function (DUF4795) FAS_N PF17828.1 EAX68828.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4140 PF13600.6 EAX68828.1 - 0.13 12.7 1.3 0.19 12.2 1.3 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2939 PF11159.8 EAX68829.1 - 0.016 15.6 0.6 0.019 15.4 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX68829.1 - 3.3 7.7 6.2 3.7 7.5 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX68830.1 - 2.1e-100 335.2 7.4 2.4e-100 335.0 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX68832.1 - 5.2e-05 22.8 2.6 8.4e-05 22.1 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX68832.1 - 0.0072 16.3 0.8 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX68832.1 - 0.021 14.4 0.2 0.044 13.4 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX68832.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PapD_N PF00345.20 EAX68833.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX68833.1 - 0.033 14.2 0.4 0.044 13.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX68833.1 - 0.059 13.4 0.2 0.074 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX68834.1 - 0.012 16.0 0.7 0.015 15.7 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68834.1 - 1.8 7.5 4.4 1.8 7.5 4.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68834.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX68834.1 - 6.4 6.8 7.6 6.9 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 YmaF PF12788.7 EAX68837.1 - 0.24 12.0 2.0 7.8 7.1 0.2 2.1 1 1 0 1 1 1 0 YmaF family Trypan_PARP PF05887.11 EAX68841.1 - 0.039 13.9 10.3 0.045 13.7 10.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) APP_amyloid PF10515.9 EAX68841.1 - 0.11 13.0 0.7 0.17 12.4 0.7 1.5 1 1 0 1 1 1 0 Beta-amyloid precursor protein C-terminus MGC-24 PF05283.11 EAX68841.1 - 4.8 7.6 6.6 6 7.3 6.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX68842.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68842.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX68843.1 - 2.1e-10 40.1 2.2 9.8e-10 37.9 2.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68843.1 - 0.11 12.5 0.0 0.92 9.5 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Pox_A32 PF04665.12 EAX68844.1 - 1.6e-08 34.3 1.0 3.5e-08 33.2 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX68844.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX68844.1 - 0.068 13.1 2.4 0.11 12.4 2.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Thymosin PF01290.20 EAX68845.1 - 0.051 13.3 0.1 46 3.8 0.0 3.7 4 0 0 4 4 4 0 Thymosin beta-4 family MORN_2 PF07661.13 EAX68845.1 - 0.1 12.9 0.0 41 4.9 0.0 3.5 5 0 0 5 5 5 0 MORN repeat variant DUF3653 PF12375.8 EAX68845.1 - 0.14 12.2 1.1 59 3.9 0.0 3.6 4 1 0 4 4 4 0 Phage protein DUF2689 PF10894.8 EAX68845.1 - 0.2 11.4 2.5 2.9 7.7 0.1 3.1 2 2 1 4 4 4 0 Protein of unknown function (DUF2689) Pox_A32 PF04665.12 EAX68847.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein PTR PF12789.7 EAX68848.1 - 1.3e-08 34.8 2.5 1.3e-08 34.8 2.5 2.9 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX68848.1 - 0.014 15.0 0.2 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 EAX68849.1 - 3.7e-106 347.9 51.2 7.5e-17 61.7 1.2 6.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX68849.1 - 1.2e-69 229.8 32.4 6.2e-13 49.0 0.3 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX68849.1 - 2e-66 219.2 25.2 1.2e-10 41.4 0.2 6.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX68849.1 - 1.3e-62 200.3 14.2 2.6e-06 27.3 0.1 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EAX68849.1 - 2.5e-60 198.4 20.5 1.3e-07 31.7 0.1 9.2 10 0 0 10 10 10 8 Ankyrin repeat MetallophosN PF16371.5 EAX68849.1 - 1.1e-09 38.4 0.0 52 4.2 0.0 7.8 1 1 7 8 8 8 0 N terminal of Calcineurin-like phosphoesterase Arg_repressor PF01316.21 EAX68849.1 - 1.5e-05 24.7 2.3 76 3.2 0.0 6.8 8 0 0 8 8 8 0 Arginine repressor, DNA binding domain Glyco_hydro_20b PF02838.15 EAX68849.1 - 6.1e-05 23.8 4.4 4.8 8.0 0.1 5.1 1 1 6 7 7 7 1 Glycosyl hydrolase family 20, domain 2 DUF3718 PF12514.8 EAX68849.1 - 0.00036 20.6 14.8 2.2 8.5 0.1 7.1 4 3 4 8 8 8 1 Protein of unknown function (DUF3718) DUF3677 PF12432.8 EAX68849.1 - 0.00038 20.7 0.0 67 3.9 0.0 6.1 1 1 6 8 8 8 0 Protein of unknown function (DUF3677) Stap_Strp_toxin PF01123.20 EAX68849.1 - 0.00043 21.1 12.4 10 7.1 0.1 6.2 1 1 7 8 8 8 1 Staphylococcal/Streptococcal toxin, OB-fold domain S4 PF01479.25 EAX68849.1 - 0.0009 18.9 0.3 59 3.5 0.0 5.5 7 0 0 7 7 7 0 S4 domain DUF1861 PF08950.10 EAX68849.1 - 0.009 15.3 0.0 21 4.2 0.0 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1861) Herpes_UL36 PF03586.13 EAX68849.1 - 0.057 12.7 0.2 5.4 6.3 0.0 2.9 1 1 1 3 3 3 0 Herpesvirus UL36 tegument protein Trypan_PARP PF05887.11 EAX68850.1 - 0.042 13.8 11.0 0.062 13.3 11.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX68850.1 - 8.4 3.9 14.8 11 3.5 14.8 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Imm59 PF15597.6 EAX68851.1 - 0.02 15.3 0.7 0.94 10.0 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 59 DUF347 PF03988.12 EAX68851.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) CD99L2 PF12301.8 EAX68851.1 - 0.14 12.5 0.8 0.24 11.7 0.1 1.7 1 1 1 2 2 2 0 CD99 antigen like protein 2 Amidase02_C PF12123.8 EAX68854.1 - 0.0025 17.5 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase HTH_6 PF01418.17 EAX68855.1 - 0.065 13.2 0.9 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DHC PF09626.10 EAX68855.1 - 3 8.8 6.1 47 4.9 2.0 3.0 1 1 3 4 4 4 0 Dihaem cytochrome c PGBA_C PF15437.6 EAX68855.1 - 6.7 7.2 10.0 0.79 10.1 1.2 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DNA_pol_B_2 PF03175.13 EAX68856.1 - 5.9e-21 74.9 4.8 1e-20 74.1 4.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral VirE PF05272.11 EAX68857.1 - 0.00046 20.0 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX68857.1 - 0.064 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX68857.1 - 0.096 11.6 0.2 8.4 5.2 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain La PF05383.17 EAX68858.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 La domain MULE PF10551.9 EAX68859.1 - 6.7e-07 29.6 0.1 1.1e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF3839 PF12943.7 EAX68860.1 - 3e-123 410.0 12.0 3.3e-123 409.8 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX68860.1 - 0.15 12.4 0.9 0.32 11.3 0.9 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Zn_ribbon_recom PF13408.6 EAX68860.1 - 9.9 6.8 8.5 32 5.1 3.8 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF4107 PF13389.6 EAX68861.1 - 3.3e-72 241.9 3.8 5e-72 241.4 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX68862.1 - 4.3e-10 39.0 3.0 2.2e-09 36.7 3.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX68862.1 - 0.13 12.2 0.0 0.92 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX68862.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_A32 PF04665.12 EAX68863.1 - 1.6e-07 31.0 0.8 2e-07 30.7 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68863.1 - 0.0043 16.7 0.1 0.0063 16.2 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68863.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68863.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Mito_fiss_reg PF05308.11 EAX68864.1 - 0.092 12.8 0.4 0.097 12.7 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator ResIII PF04851.15 EAX68865.1 - 4e-05 23.7 2.4 8.3e-05 22.7 2.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68865.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68865.1 - 0.00038 20.8 0.0 0.00063 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68865.1 - 0.00079 19.3 1.2 0.0024 17.7 1.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68865.1 - 0.0066 16.8 0.0 0.0089 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX68865.1 - 0.039 13.7 0.2 0.24 11.1 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX68865.1 - 0.04 13.4 0.1 0.084 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX68865.1 - 0.074 13.3 4.8 1.4 9.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX68865.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68865.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pox_D5 PF03288.16 EAX68868.1 - 4.2e-05 24.0 2.4 0.00019 21.8 2.4 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX68869.1 - 1.3e-53 180.8 3.9 1.4e-53 180.7 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX68871.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4116 PF13475.6 EAX68872.1 - 0.025 14.3 2.4 0.031 14.0 0.1 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4116) Transposase_24 PF03004.14 EAX68872.1 - 0.7 10.0 5.1 1.2 9.2 1.4 2.4 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) TbpB_A PF17484.2 EAX68872.1 - 3.3 8.5 8.2 9.1 7.0 8.2 1.8 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B DUF4107 PF13389.6 EAX68874.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX68875.1 - 0.033 14.6 0.5 0.064 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX68876.1 - 3.8e-66 222.2 5.6 5.9e-66 221.6 5.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68876.1 - 0.11 12.9 0.5 0.15 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX68877.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX68878.1 - 1.4e-23 83.6 7.5 1.2e-22 80.4 7.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral TMP PF05017.14 EAX68880.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX68881.1 - 0.057 13.9 0.5 0.13 12.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX68882.1 - 4.4e-58 195.3 3.9 4.8e-58 195.1 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX68882.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF2897 PF11446.8 EAX68883.1 - 0.26 11.2 2.1 0.5 10.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX68885.1 - 9.2e-128 424.7 7.7 1.1e-127 424.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68885.1 - 0.5 10.9 2.7 1.2 9.7 1.4 2.3 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX68887.1 - 0.0093 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4795 PF16043.5 EAX68888.1 - 0.011 15.3 1.6 0.028 14.0 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX68888.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.4 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX68888.1 - 0.086 13.0 12.8 3.3 8.1 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX68888.1 - 1.2 9.7 5.9 18 6.0 0.2 3.3 3 1 0 3 3 3 0 YmaF family SRP54 PF00448.22 EAX68890.1 - 0.14 11.8 1.3 3.1 7.4 0.2 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain TFIIA PF03153.13 EAX68890.1 - 1 9.3 22.3 1.3 8.9 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Staufen_C PF16482.5 EAX68890.1 - 1.1 9.5 10.8 0.39 10.9 1.4 3.4 1 1 2 3 3 3 0 Staufen C-terminal domain AMPKBI PF04739.15 EAX68890.1 - 2.6 8.4 21.3 12 6.3 0.6 4.2 2 2 1 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain SHIRT PF18655.1 EAX68890.1 - 7 7.3 10.8 0.58 10.8 0.3 3.4 3 1 1 4 4 4 0 SHIRT domain DUF4107 PF13389.6 EAX68892.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) FNIP_M PF14637.6 EAX68893.1 - 0.032 14.2 0.1 0.051 13.6 0.0 1.2 1 1 0 1 1 1 0 Folliculin-interacting protein middle domain MULE PF10551.9 EAX68897.1 - 1.1e-10 41.8 2.6 2.1e-10 40.9 0.2 2.7 3 0 0 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX68897.1 - 0.0056 16.4 0.5 0.038 13.7 0.3 2.2 1 1 1 2 2 2 1 Transposase Transposase_mut PF00872.18 EAX68897.1 - 0.06 12.2 2.6 0.21 10.4 2.6 1.8 1 1 0 1 1 1 0 Transposase, Mutator family DUF2960 PF11173.8 EAX68897.1 - 0.073 13.5 1.4 0.11 12.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) TMP PF05017.14 EAX68899.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF938 PF06080.12 EAX68900.1 - 0.033 13.9 0.0 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF938) TetR_C_23 PF17931.1 EAX68900.1 - 5.8 7.1 6.2 18 5.4 1.5 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Spc7 PF08317.11 EAX68900.1 - 7.3 5.4 14.2 0.9 8.4 6.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Pox_A32 PF04665.12 EAX68901.1 - 1.7e-07 30.9 1.7 2.1e-07 30.7 1.7 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68901.1 - 0.003 17.2 0.2 0.0033 17.1 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68901.1 - 0.054 13.2 0.1 0.17 11.6 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68901.1 - 0.11 12.5 0.2 0.91 9.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX68901.1 - 0.82 9.9 7.6 3.6 7.8 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX68902.1 - 2.8e-117 390.4 12.0 3.6e-117 390.1 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX68902.1 - 0.1 13.2 0.5 0.19 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX68902.1 - 0.12 12.9 4.2 1.4 9.4 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX68902.1 - 0.42 11.0 0.1 0.42 11.0 0.1 2.8 4 0 0 4 4 4 0 PRD domain Amidase02_C PF12123.8 EAX68903.1 - 0.0035 17.0 0.0 0.0096 15.6 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3417 PF11897.8 EAX68904.1 - 0.11 13.0 0.1 0.13 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX68905.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX68906.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX68909.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein ResIII PF04851.15 EAX68910.1 - 5.3e-05 23.3 0.1 7.4e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX68910.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX68910.1 - 0.0021 18.4 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX68910.1 - 0.0023 17.7 0.0 0.0029 17.4 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX68910.1 - 0.0038 17.6 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68910.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX68910.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX68910.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX68910.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 EAX68911.1 - 0.22 11.5 5.1 0.29 11.1 5.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.13 EAX68913.1 - 2.4e-17 63.0 3.6 4.1e-17 62.2 3.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX68913.1 - 0.021 14.2 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX68913.1 - 0.033 14.3 1.0 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Pox_A32 PF04665.12 EAX68915.1 - 2.6e-07 30.4 1.0 1.3e-06 28.1 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX68915.1 - 0.059 13.0 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX68915.1 - 0.097 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF3839 PF12943.7 EAX68916.1 - 1.7e-116 387.9 7.6 1.9e-116 387.7 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX68917.1 - 1.5e-42 144.9 2.9 1.7e-42 144.8 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX68917.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF5106 PF17127.4 EAX68919.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Tho2 PF11262.8 EAX68920.1 - 0.047 12.9 1.7 0.051 12.8 1.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX68920.1 - 0.53 10.2 8.3 0.21 11.5 2.9 2.5 3 0 0 3 3 3 0 Spo12 family Gly-zipper_Omp PF13488.6 EAX68922.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX68922.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX68922.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Gly-zipper_Omp PF13488.6 EAX68923.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX68923.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) FAS_N PF17828.1 EAX68924.1 - 0.012 15.6 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX68925.1 - 1.9e-86 289.5 5.1 2.1e-86 289.3 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX68926.1 - 2.8e-10 40.0 0.0 7.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX68928.1 - 3e-157 521.3 12.2 3.7e-157 521.0 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX68928.1 - 0.032 14.7 1.9 0.069 13.6 0.5 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX68928.1 - 0.17 12.2 2.7 11 6.4 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX68928.1 - 0.64 10.5 6.3 2.1 8.8 0.4 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RPA_C PF08784.11 EAX68929.1 - 0.0042 17.7 0.0 0.0077 16.9 0.0 1.5 1 1 0 1 1 1 1 Replication protein A C terminal RMI2 PF16100.5 EAX68929.1 - 0.03 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 PqqD PF05402.12 EAX68929.1 - 0.2 12.0 0.4 29 5.1 0.1 2.3 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) BsuBI_PstI_RE PF06616.11 EAX68930.1 - 0.13 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain TMP PF05017.14 EAX68931.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat HD_2 PF12917.7 EAX68932.1 - 0.091 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF2939 PF11159.8 EAX68933.1 - 0.021 15.2 0.7 0.032 14.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68933.1 - 2.1 7.3 4.5 2.2 7.2 4.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68933.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX68933.1 - 7.6 6.5 8.1 8.2 6.4 8.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ResIII PF04851.15 EAX68935.1 - 2.1e-05 24.6 1.0 4.1e-05 23.7 1.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX68935.1 - 0.0003 20.6 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX68935.1 - 0.00039 20.7 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX68935.1 - 0.0012 18.7 0.2 0.0019 18.0 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX68935.1 - 0.0064 16.8 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX68935.1 - 0.036 13.5 0.1 0.049 13.1 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX68935.1 - 0.061 13.0 0.4 0.099 12.3 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX68935.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX68935.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX68935.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX68935.1 - 0.7 10.3 3.4 0.43 11.0 0.6 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 BspA_v PF18220.1 EAX68936.1 - 0.61 10.2 4.5 4.5 7.4 0.5 2.4 2 0 0 2 2 2 0 Adhesin BspA variable domain PSP PF04046.16 EAX68937.1 - 0.037 13.9 0.8 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX68938.1 - 0.17 12.6 6.3 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4116 PF13475.6 EAX68940.1 - 0.019 14.7 1.0 0.055 13.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX68940.1 - 0.064 13.7 4.5 0.091 13.2 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX68940.1 - 0.13 12.0 6.0 0.13 12.0 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PTR PF12789.7 EAX68940.1 - 0.22 11.6 0.1 0.22 11.6 0.1 4.2 4 1 0 4 4 4 0 Phage tail repeat like Trypan_PARP PF05887.11 EAX68941.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68941.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX68942.1 - 2.8e-25 89.2 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX68942.1 - 0.057 13.9 0.2 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PRE_C2HC PF07530.11 EAX68942.1 - 0.064 13.4 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers Amidase02_C PF12123.8 EAX68943.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase IKKbetaNEMObind PF12179.8 EAX68944.1 - 0.18 11.8 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Amidase02_C PF12123.8 EAX68945.1 - 0.0053 16.4 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX68945.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF1493 PF07377.12 EAX68946.1 - 0.092 13.2 0.7 0.2 12.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3653 PF12375.8 EAX68948.1 - 0.003 17.6 0.4 5.2 7.3 0.0 3.1 3 0 0 3 3 3 2 Phage protein GPS2_interact PF15784.5 EAX68949.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX68949.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX68950.1 - 0.042 13.8 7.8 0.065 13.2 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX68950.1 - 2.6 8.5 4.7 3.7 8.0 4.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX68951.1 - 1.5e-56 191.6 3.5 1.7e-56 191.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX68952.1 - 1.1e-116 388.4 6.8 1.3e-116 388.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX68952.1 - 0.12 12.8 1.0 0.82 10.2 0.3 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Z1 PF10593.9 EAX68952.1 - 0.13 11.8 0.3 0.17 11.3 0.3 1.3 1 1 0 1 1 1 0 Z1 domain PTR PF12789.7 EAX68953.1 - 1.2e-10 41.3 5.8 1.1e-08 34.9 1.4 4.9 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX68953.1 - 0.01 15.5 12.8 0.024 14.2 1.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX68953.1 - 0.52 10.9 9.4 31 5.2 0.1 4.1 4 1 0 4 4 4 0 YmaF family ATR13 PF16829.5 EAX68953.1 - 0.71 10.3 4.8 1.3 9.5 2.5 2.3 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Phage_fiber PF03335.13 EAX68953.1 - 8.5 6.8 24.5 4.6 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat Meiosis_expr PF15163.6 EAX68955.1 - 0.035 14.8 1.0 0.052 14.2 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX68955.1 - 0.14 11.9 0.1 0.55 10.0 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX68955.1 - 1.6 8.7 11.0 0.18 11.7 2.9 2.9 4 0 0 4 4 4 0 Spo12 family KilA-N PF04383.13 EAX68957.1 - 1.1e-14 54.2 1.9 1.4e-14 53.9 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX68957.1 - 0.002 18.7 0.0 0.0044 17.6 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX68958.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX68958.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX68958.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX68958.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Mito_fiss_reg PF05308.11 EAX68959.1 - 0.1 12.7 0.5 0.11 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3839 PF12943.7 EAX68960.1 - 4.8e-120 399.5 11.6 6.1e-120 399.1 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX68960.1 - 0.097 12.5 1.0 0.31 10.9 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX68960.1 - 0.22 12.0 2.0 5.3 7.6 0.0 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX68961.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX68962.1 - 5.6e-21 74.4 7.3 5.6e-21 74.4 7.3 3.2 2 1 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX68962.1 - 0.019 14.7 0.1 0.072 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) KilA-N PF04383.13 EAX68963.1 - 3.3e-43 146.1 0.1 4.8e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain PGP_phosphatase PF09419.10 EAX68964.1 - 0.011 15.4 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase nsp7 PF08716.10 EAX68964.1 - 0.23 12.1 1.3 0.74 10.5 0.1 2.4 2 1 1 3 3 3 0 nsp7 replicase DUF2672 PF10878.8 EAX68964.1 - 7.3 6.6 10.1 0.14 12.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) DUF4107 PF13389.6 EAX68965.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX68965.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX68966.1 - 3.3e-07 30.0 0.2 3.8e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein DUF4106 PF13388.6 EAX68968.1 - 1.2e-174 581.5 37.4 1.8e-172 574.3 37.4 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX68968.1 - 0.068 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TMP PF05017.14 EAX68970.1 - 0.029 14.9 6.1 2.6 9.1 0.4 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX68971.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX68973.1 - 2.9e-09 36.8 1.8 2.9e-09 36.8 1.8 3.5 4 2 0 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX68973.1 - 0.079 13.5 4.1 17 6.0 0.0 3.4 3 1 0 3 3 3 0 YmaF family ATR13 PF16829.5 EAX68973.1 - 0.29 11.5 4.0 0.46 10.9 2.3 2.1 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector DUF4795 PF16043.5 EAX68973.1 - 0.35 10.4 14.5 3.3 7.3 2.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX68973.1 - 3.6 8.0 16.9 4.2 7.8 2.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX68975.1 - 1.2e-08 34.8 0.7 1.2e-08 34.8 0.7 3.8 2 1 2 4 4 4 1 Phage tail repeat like DUF3417 PF11897.8 EAX68975.1 - 0.022 15.2 3.5 0.31 11.5 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) DUF167 PF02594.16 EAX68975.1 - 0.099 12.8 0.6 4.6 7.4 0.2 2.7 1 1 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 EDR1 PF14381.6 EAX68975.1 - 0.13 12.0 3.7 0.76 9.5 0.7 2.1 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 FAM76 PF16046.5 EAX68975.1 - 4.5 6.5 10.4 6.5 6.0 10.4 1.3 1 0 0 1 1 1 0 FAM76 protein LIN52 PF10044.9 EAX68975.1 - 7.1 7.4 7.0 26 5.6 0.5 2.5 1 1 1 2 2 2 0 Retinal tissue protein Mito_fiss_reg PF05308.11 EAX68976.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX68976.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_A32 PF04665.12 EAX68977.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX68977.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX68978.1 - 2.9e-25 89.2 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX68978.1 - 0.063 13.7 0.3 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF2939 PF11159.8 EAX68980.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX68980.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX68980.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain La PF05383.17 EAX68981.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 La domain VirE PF05272.11 EAX68983.1 - 1.8e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX68983.1 - 0.00012 22.5 1.6 0.00062 20.2 1.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX68983.1 - 0.064 13.7 0.3 0.16 12.3 0.1 1.8 1 1 1 2 2 2 0 RNA helicase DUF3198 PF11433.8 EAX68983.1 - 0.14 12.1 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) La PF05383.17 EAX68984.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 La domain DNA_pol_B_2 PF03175.13 EAX68985.1 - 2.1e-21 76.3 8.5 1e-20 74.1 8.5 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX68985.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Ank_4 PF13637.6 EAX68989.1 - 5.9e-34 116.0 3.3 4.8e-10 39.8 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX68989.1 - 1e-33 115.8 1.1 2e-13 50.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX68989.1 - 1e-30 105.4 0.2 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX68989.1 - 5.3e-26 87.8 0.9 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX68989.1 - 1.1e-21 76.3 5.2 0.00026 21.3 0.0 6.7 6 1 1 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX68989.1 - 0.0025 17.7 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX68989.1 - 0.063 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase PSP PF04046.16 EAX68990.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX68992.1 - 0.015 15.3 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX68993.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF2897 PF11446.8 EAX68995.1 - 0.056 13.3 2.1 0.1 12.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX68995.1 - 0.1 13.1 0.2 0.12 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX68996.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX68997.1 - 1.7e-05 25.2 0.4 2.9e-05 24.5 0.4 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX68997.1 - 0.026 15.1 0.2 0.035 14.7 0.2 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX68997.1 - 0.079 12.9 0.3 0.12 12.4 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain Amidase02_C PF12123.8 EAX69000.1 - 0.0084 15.8 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX69001.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX69004.1 - 5.1e-05 23.3 2.2 9.7e-05 22.4 2.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69004.1 - 0.00034 20.4 0.0 0.00045 20.0 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX69004.1 - 0.00039 20.7 0.0 0.00063 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX69004.1 - 0.00076 19.3 0.9 0.0025 17.7 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69004.1 - 0.007 16.7 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69004.1 - 0.035 13.6 0.1 0.056 12.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX69004.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2939 PF11159.8 EAX69006.1 - 0.0031 17.9 0.3 0.0042 17.4 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) DNA_pol_B PF00136.21 EAX69008.1 - 0.091 11.4 0.3 0.1 11.2 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B DUF3839 PF12943.7 EAX69009.1 - 1.1e-144 480.2 13.3 1.4e-144 479.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69009.1 - 0.012 16.0 0.2 0.098 13.1 0.0 2.0 2 0 0 2 2 2 0 Fez1 Bot1p PF12298.8 EAX69009.1 - 0.083 13.1 0.0 0.59 10.3 0.0 2.2 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein GCN5L1 PF06320.13 EAX69009.1 - 0.11 12.7 0.4 0.67 10.1 0.1 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Rx_N PF18052.1 EAX69009.1 - 0.37 11.1 2.4 1.7 9.0 0.0 2.9 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX69009.1 - 0.8 10.2 5.9 2.1 8.8 1.2 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMBR1 PF04791.16 EAX69011.1 - 4.8 6.0 10.6 7.5 5.3 10.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ArsC PF03960.15 EAX69011.1 - 7 6.7 8.4 0.63 10.1 0.7 2.9 2 2 0 2 2 2 0 ArsC family GDE_C PF06202.14 EAX69012.1 - 0.011 14.7 0.7 2.7 6.8 0.1 2.1 1 1 1 2 2 2 0 Amylo-alpha-1,6-glucosidase Tho2 PF11262.8 EAX69015.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pox_A32 PF04665.12 EAX69016.1 - 7.6e-05 22.3 4.2 0.00013 21.5 4.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69016.1 - 0.0037 17.3 0.8 0.0079 16.2 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69016.1 - 0.011 15.3 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX69016.1 - 0.04 14.2 0.8 0.15 12.4 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF4108 PF13390.6 EAX69017.1 - 7.7e-63 210.7 7.8 8.6e-63 210.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX69019.1 - 0.077 13.3 4.1 0.096 13.0 4.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PapD_N PF00345.20 EAX69020.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4106 PF13388.6 EAX69021.1 - 1.6e-96 324.2 4.8 1.6e-96 324.2 4.8 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX69021.1 - 0.13 10.8 3.6 0.15 10.6 3.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3452 PF11934.8 EAX69021.1 - 0.16 11.6 1.0 0.26 10.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX69021.1 - 2.5 8.1 4.7 0.57 10.2 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) JMY PF15871.5 EAX69022.1 - 0.013 14.8 0.3 0.018 14.4 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4107 PF13389.6 EAX69023.1 - 3.9e-33 114.9 3.2 7.3e-33 114.0 3.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) B3R PF17057.5 EAX69024.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxviridae B3 protein SH3_5 PF08460.10 EAX69024.1 - 0.058 13.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain DUF4108 PF13390.6 EAX69026.1 - 1.7e-62 209.6 6.1 1.9e-62 209.4 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX69027.1 - 0.53 10.2 3.4 0.71 9.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX69028.1 - 2.6e-23 81.8 7.7 2.6e-23 81.8 7.7 4.5 2 2 2 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX69028.1 - 0.051 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) SAS4 PF15460.6 EAX69028.1 - 0.16 12.1 6.2 5.7 7.1 0.2 2.6 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 HTH_11 PF08279.12 EAX69030.1 - 0.13 12.2 0.1 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX69030.1 - 1.1 9.3 4.5 0.46 10.5 0.6 2.3 2 2 1 3 3 3 0 Domain of unknown function (DUF5065) DUF3221 PF11518.8 EAX69031.1 - 0.027 14.8 1.2 0.051 13.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) Pox_A32 PF04665.12 EAX69032.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Mucin-like PF16058.5 EAX69033.1 - 1.6e-48 162.9 14.8 8.9e-14 51.4 0.1 3.0 1 1 3 4 4 4 4 Mucin-like DUF4275 PF14101.6 EAX69033.1 - 0.018 15.2 23.8 8.3 6.5 1.4 5.9 1 1 4 6 6 6 0 Domain of unknown function (DUF4275) BOF PF04076.13 EAX69033.1 - 0.02 15.0 31.5 4.7 7.3 4.9 4.4 1 1 6 7 7 7 0 Bacterial OB fold (BOF) protein DUF2501 PF10696.9 EAX69033.1 - 0.1 12.9 28.4 11 6.4 0.7 5.6 1 1 8 9 9 9 0 Protein of unknown function (DUF2501) RNaseH_like PF04308.12 EAX69033.1 - 1.7 8.6 20.6 30 4.5 1.8 5.4 1 1 4 5 5 5 0 Ribonuclease H-like Baculo_gp41 PF04700.12 EAX69033.1 - 2.4 7.9 25.3 9.2 6.0 6.7 3.1 1 1 2 3 3 3 0 Structural glycoprotein p40/gp41 conserved region SPAR_C PF11881.8 EAX69033.1 - 6.2 6.7 23.7 41 4.0 1.4 5.4 1 1 1 2 2 2 0 C-terminal domain of SPAR protein Phage_fiber PF03335.13 EAX69034.1 - 6 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Chal_sti_synt_N PF00195.19 EAX69035.1 - 0.042 13.3 0.6 0.066 12.6 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX69036.1 - 5.3e-40 137.4 3.9 7.2e-40 137.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4795 PF16043.5 EAX69037.1 - 0.019 14.6 3.5 0.05 13.2 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX69037.1 - 0.029 14.4 2.0 0.029 14.4 2.0 3.4 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX69037.1 - 4.2 7.8 16.2 4 7.9 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF2939 PF11159.8 EAX69038.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69038.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69038.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69039.1 - 0.042 13.8 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta S1_2 PF13509.6 EAX69039.1 - 0.097 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 S1 domain Trypan_PARP PF05887.11 EAX69040.1 - 0.093 12.7 6.6 0.14 12.1 6.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69040.1 - 2.5 8.5 5.1 3.6 8.0 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX69042.1 - 2.5e-25 89.3 4.3 3.8e-25 88.8 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX69042.1 - 0.092 11.9 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II RecO_C PF02565.15 EAX69042.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal KilA-N PF04383.13 EAX69043.1 - 4.9e-09 36.0 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX69043.1 - 0.15 11.4 0.2 0.3 10.5 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX69043.1 - 1.2 9.5 4.7 4.2 7.7 0.4 2.3 1 1 0 2 2 2 0 PRD domain EssA PF10661.9 EAX69043.1 - 3.5 7.4 7.8 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA KilA-N PF04383.13 EAX69045.1 - 6.6e-36 122.6 0.7 1.3e-35 121.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69045.1 - 0.031 14.9 0.6 0.098 13.3 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family GPS2_interact PF15784.5 EAX69046.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Gly-zipper_Omp PF13488.6 EAX69049.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX69049.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX69049.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PSP PF04046.16 EAX69051.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69052.1 - 0.17 12.6 6.3 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat AAA_22 PF13401.6 EAX69054.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69054.1 - 8.2e-05 22.7 3.1 0.00015 21.8 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69054.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69054.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69054.1 - 0.003 17.3 0.3 0.3 10.8 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX69054.1 - 0.0077 16.6 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69054.1 - 0.048 13.1 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69054.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69054.1 - 0.093 13.2 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69054.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69054.1 - 0.2 11.9 4.6 4.1 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) YmaF PF12788.7 EAX69055.1 - 0.19 12.3 1.5 13 6.4 0.1 2.1 1 1 0 2 2 2 0 YmaF family Actin PF00022.19 EAX69056.1 - 2.8e-132 441.2 0.0 1.1e-131 439.2 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX69056.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT T5orf172 PF10544.9 EAX69060.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PapD_N PF00345.20 EAX69062.1 - 0.034 14.1 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69062.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX69062.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4106 PF13388.6 EAX69063.1 - 2.2e-196 653.1 18.0 2.7e-196 652.8 18.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX69063.1 - 0.0075 16.5 0.1 0.43 10.9 0.2 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX69063.1 - 0.11 13.2 0.7 0.25 11.9 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit Gly-zipper_Omp PF13488.6 EAX69064.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX69064.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX69064.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DNA_pol_B_2 PF03175.13 EAX69066.1 - 3.4e-20 72.4 4.1 6.2e-20 71.5 4.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69066.1 - 0.019 14.3 0.2 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX69066.1 - 0.26 11.3 1.5 5.4 7.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF1493 PF07377.12 EAX69067.1 - 0.045 14.2 0.8 0.095 13.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX69068.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69068.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69068.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69068.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69068.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69068.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69068.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69068.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX69068.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX69068.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69068.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69068.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69068.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MULE PF10551.9 EAX69070.1 - 6.3e-10 39.4 0.2 1e-09 38.7 0.2 1.4 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX69070.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EAX69070.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF1196 PF06709.11 EAX69070.1 - 0.53 10.5 2.3 1.8 8.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1196) Tubulin_C PF03953.17 EAX69071.1 - 1.5e-50 170.5 0.0 2.5e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 EAX69071.1 - 3.9e-42 144.7 0.0 5.9e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 EAX69071.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAX69071.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2939 PF11159.8 EAX69073.1 - 0.021 15.2 0.7 0.027 14.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69073.1 - 1.7 7.6 4.2 1.8 7.5 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69073.1 - 7 6.6 7.6 7.6 6.5 7.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69074.1 - 0.0086 16.1 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DDE_Tnp_4 PF13359.6 EAX69076.1 - 2.3e-20 72.8 0.1 3.3e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX69076.1 - 6.2e-06 26.0 0.1 9.9e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX69076.1 - 1.4e-05 24.7 0.8 0.00068 19.3 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease Pox_A32 PF04665.12 EAX69077.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69077.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69077.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69077.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PapD_N PF00345.20 EAX69078.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX69079.1 - 0.024 15.1 0.8 0.033 14.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69079.1 - 1.3 9.0 5.1 1.4 8.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX69081.1 - 2e-05 24.5 0.4 2e-05 24.5 0.4 4.0 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX69081.1 - 0.027 14.2 0.9 0.074 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX69081.1 - 0.054 13.2 0.2 2.9 7.6 0.1 2.4 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX69081.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX69081.1 - 0.26 11.1 11.1 0.7 9.6 11.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) KilA-N PF04383.13 EAX69082.1 - 4.7e-18 65.1 0.2 6e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX69082.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Trypan_PARP PF05887.11 EAX69083.1 - 0.079 12.9 10.7 0.12 12.3 10.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX69084.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69084.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX69085.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Spo12 PF05032.12 EAX69086.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family FAS_N PF17828.1 EAX69088.1 - 0.0095 15.9 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HI0933_like PF03486.14 EAX69088.1 - 0.21 10.3 0.7 0.26 9.9 0.7 1.0 1 0 0 1 1 1 0 HI0933-like protein DNA_pol_B_2 PF03175.13 EAX69089.1 - 1.1e-22 80.6 4.1 1.5e-22 80.2 4.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX69091.1 - 1.8e-21 76.6 4.0 2.4e-21 76.2 4.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral EpuA PF11772.8 EAX69092.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4107 PF13389.6 EAX69093.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Arm-DNA-bind_5 PF17293.2 EAX69094.1 - 0.012 16.1 0.8 0.012 16.1 0.8 2.5 2 1 0 2 2 2 0 Arm DNA-binding domain FAS_N PF17828.1 EAX69095.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69096.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69096.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX69097.1 - 2.4e-22 79.4 4.1 3.1e-22 79.1 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ACP_PD PF04336.12 EAX69098.1 - 0.024 15.0 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Pox_A32 PF04665.12 EAX69099.1 - 3.4e-06 26.7 2.3 3.4e-06 26.7 2.3 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX69099.1 - 3.8e-05 23.5 0.2 0.4 10.4 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69099.1 - 4.2e-05 23.8 0.2 0.00038 20.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69099.1 - 0.00033 20.7 4.4 0.00066 19.7 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69099.1 - 0.00072 19.4 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69099.1 - 0.0015 18.3 0.5 0.0042 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69099.1 - 0.0043 16.7 2.2 0.012 15.3 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69099.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69099.1 - 0.09 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX69099.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX69099.1 - 0.12 12.8 0.5 0.93 9.9 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX69099.1 - 0.42 11.3 10.6 0.29 11.8 1.4 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX69099.1 - 0.62 10.3 4.5 9.6 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69100.1 - 1.1e-78 264.0 10.8 1.5e-78 263.6 10.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX69100.1 - 0.2 11.2 0.7 1.1 8.7 0.0 2.3 2 1 1 3 3 3 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX69100.1 - 0.28 11.1 2.0 0.84 9.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX69103.1 - 5.5e-33 113.2 0.2 1.9e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Viral_P18 PF04521.13 EAX69104.1 - 0.0036 17.1 0.0 2.9 7.7 0.0 2.1 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein Amidase02_C PF12123.8 EAX69105.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69105.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4106 PF13388.6 EAX69106.1 - 5.5e-195 648.5 16.8 6.4e-195 648.3 16.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX69106.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Phosphonate-bd PF12974.7 EAX69106.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Nucleo_P87 PF07267.11 EAX69106.1 - 1.9 7.3 6.1 3.5 6.4 6.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ndc1_Nup PF09531.10 EAX69106.1 - 9.3 4.8 6.3 15 4.1 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Amidase02_C PF12123.8 EAX69107.1 - 0.00078 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX69109.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69110.1 - 0.037 14.6 4.0 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX69112.1 - 2.2e-74 246.1 36.6 5.9e-12 46.0 0.3 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX69112.1 - 1.4e-55 185.0 14.3 2.5e-12 47.0 0.1 8.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX69112.1 - 4.7e-42 140.6 18.4 4e-05 23.9 0.0 9.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 EAX69112.1 - 6.4e-37 121.4 11.6 3.8e-05 23.7 0.1 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 EAX69112.1 - 2.2e-33 113.9 8.0 1.4e-08 34.8 0.1 4.7 2 1 3 6 6 6 6 Ankyrin repeats (many copies) PrmC_N PF17827.1 EAX69112.1 - 1.6e-06 28.6 6.0 71 4.1 0.0 7.1 7 2 1 8 8 8 0 PrmC N-terminal domain MetallophosN PF16371.5 EAX69112.1 - 3.5e-06 27.2 0.0 47 4.3 0.0 7.1 1 1 7 8 8 8 0 N terminal of Calcineurin-like phosphoesterase RGP PF03214.13 EAX69112.1 - 7e-06 25.4 0.0 13 4.8 0.0 5.7 1 1 6 7 7 7 1 Reversibly glycosylated polypeptide DUF3677 PF12432.8 EAX69112.1 - 3.1e-05 24.2 0.0 26 5.2 0.0 6.2 1 1 7 8 8 8 0 Protein of unknown function (DUF3677) DUF3718 PF12514.8 EAX69112.1 - 0.11 12.7 10.9 52 4.1 0.1 7.0 1 1 6 7 7 7 0 Protein of unknown function (DUF3718) VPS11_C PF12451.8 EAX69112.1 - 0.12 12.6 14.7 85 3.5 0.1 6.0 6 0 0 6 6 6 0 Vacuolar protein sorting protein 11 C terminal DUF348 PF03990.14 EAX69112.1 - 0.23 11.3 9.0 2.2e+02 1.7 0.0 7.0 8 0 0 8 8 8 0 G5-linked-Ubiquitin-like domain DUF4300 PF14133.6 EAX69112.1 - 0.26 11.0 11.4 97 2.5 0.1 5.8 1 1 7 8 8 8 0 Domain of unknown function (DUF4300) DUF1103 PF06513.11 EAX69112.1 - 0.36 10.4 11.8 0.41 10.2 5.6 2.1 1 1 1 2 2 2 0 Repeat of unknown function (DUF1103) Pox_A32 PF04665.12 EAX69113.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein KilA-N PF04383.13 EAX69114.1 - 1.8e-35 121.1 0.3 5e-35 119.7 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69114.1 - 0.0052 17.4 0.0 0.013 16.1 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DDE_Tnp_4 PF13359.6 EAX69115.1 - 1e-31 109.8 0.0 1.3e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX69115.1 - 8.9e-09 35.3 0.1 4.7e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain DUF2939 PF11159.8 EAX69116.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX69116.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX69116.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69117.1 - 0.02 14.9 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX69118.1 - 7.3e-43 145.9 2.9 8e-43 145.8 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX69118.1 - 0.14 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF2897 PF11446.8 EAX69119.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX69120.1 - 1.6e-16 60.1 2.5 1.6e-16 60.1 2.5 4.0 3 1 2 5 5 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX69120.1 - 0.035 13.8 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX69120.1 - 0.077 12.9 5.0 1.5 8.7 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DNA_pol_B_2 PF03175.13 EAX69121.1 - 1.2e-21 77.2 6.0 1.2e-20 73.8 6.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69121.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX69122.1 - 7e-17 61.4 2.0 7.8e-17 61.3 2.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69122.1 - 0.068 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF2939 PF11159.8 EAX69123.1 - 0.016 15.6 0.5 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69123.1 - 1.2 9.1 5.8 1.3 9.0 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69124.1 - 0.01 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX69125.1 - 3.7e-06 26.8 0.2 3.7e-06 26.8 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69125.1 - 0.002 18.7 0.0 0.0047 17.5 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family WRKY PF03106.15 EAX69127.1 - 0.024 14.9 0.8 0.024 14.9 0.8 2.7 2 2 1 3 3 3 0 WRKY DNA -binding domain DUF2897 PF11446.8 EAX69128.1 - 1.4 8.8 3.7 2.5 8.0 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69129.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4011 PF13195.6 EAX69131.1 - 0.0043 17.0 0.4 0.0079 16.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) YmaF PF12788.7 EAX69133.1 - 0.013 16.0 1.5 0.32 11.6 1.6 2.1 1 1 0 1 1 1 0 YmaF family AAA_22 PF13401.6 EAX69135.1 - 5.4e-05 23.5 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69135.1 - 5.8e-05 23.2 2.7 0.0001 22.3 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69135.1 - 0.00036 20.3 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69135.1 - 0.0012 18.7 1.4 0.0039 17.0 1.4 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69135.1 - 0.002 17.9 0.2 0.21 11.3 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX69135.1 - 0.0071 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69135.1 - 0.047 13.2 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69135.1 - 0.063 13.0 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69135.1 - 0.094 13.1 0.1 0.38 11.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX69135.1 - 0.12 12.6 4.9 2.3 8.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX69135.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX69135.1 - 0.22 11.2 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX69135.1 - 0.93 9.9 4.4 0.41 11.1 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Pox_D5 PF03288.16 EAX69137.1 - 0.00015 22.2 2.6 0.00089 19.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX69137.1 - 0.032 13.3 1.1 0.046 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) PapD_N PF00345.20 EAX69139.1 - 0.053 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69139.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family VirE PF05272.11 EAX69140.1 - 1.4e-05 25.0 0.1 2.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX69140.1 - 4.6e-05 23.8 2.2 0.00027 21.4 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX69140.1 - 0.021 13.9 1.0 0.031 13.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX69140.1 - 0.048 14.1 0.5 0.16 12.4 0.1 2.0 1 1 0 2 2 2 0 RNA helicase DUF3198 PF11433.8 EAX69140.1 - 0.13 12.2 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) DNA_pol_B_2 PF03175.13 EAX69141.1 - 3.8e-10 39.2 2.2 3e-09 36.3 2.2 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69141.1 - 0.12 12.4 0.0 0.89 9.6 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX69141.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Gly_rich PF12810.7 EAX69142.1 - 3e-35 122.3 31.1 3.4e-35 122.1 31.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Pox_A32 PF04665.12 EAX69143.1 - 1.8e-07 30.9 3.2 2.5e-07 30.4 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69143.1 - 0.0031 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69143.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69143.1 - 0.061 13.1 0.1 0.27 11.0 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69143.1 - 0.079 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX69143.1 - 0.4 10.9 8.5 5.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) FAS_N PF17828.1 EAX69145.1 - 0.0029 17.6 0.1 0.0048 16.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DinB PF05163.12 EAX69145.1 - 0.085 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 DinB family DUF4576 PF15144.6 EAX69145.1 - 0.21 11.4 3.8 0.12 12.3 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) FYVE_2 PF02318.16 EAX69146.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4795 PF16043.5 EAX69147.1 - 0.0043 16.7 1.5 0.0059 16.2 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX69147.1 - 0.0096 16.4 2.9 0.26 11.9 0.2 2.2 1 1 0 2 2 2 2 YmaF family Phage_fiber PF03335.13 EAX69147.1 - 3.8 7.9 9.5 9.5 6.7 1.5 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX69148.1 - 2.8e-151 501.8 15.2 3.2e-151 501.6 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX69148.1 - 0.032 14.5 0.3 11 6.4 0.1 3.2 2 1 0 2 2 2 0 Tup N-terminal KELK PF15796.5 EAX69148.1 - 0.3 11.6 5.3 1 9.9 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX69149.1 - 0.0037 16.9 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX69152.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX69153.1 - 0.023 15.2 0.7 0.047 14.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Orf78 PF06024.12 EAX69154.1 - 0.032 14.5 2.7 0.052 13.9 2.7 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Med12-PQL PF12144.8 EAX69156.1 - 0.011 15.6 0.7 0.012 15.5 0.7 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Bactofilin PF04519.13 EAX69156.1 - 0.048 14.0 0.1 0.063 13.6 0.1 1.1 1 0 0 1 1 1 0 Polymer-forming cytoskeletal PG_binding_2 PF08823.11 EAX69157.1 - 0.064 13.6 0.8 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Alba PF01918.21 EAX69157.1 - 0.064 13.1 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 Alba Amidase02_C PF12123.8 EAX69158.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase MULE PF10551.9 EAX69159.1 - 1.4e-11 44.6 0.6 2.9e-11 43.6 0.6 1.5 1 0 0 1 1 1 1 MULE transposase domain L27_1 PF09058.10 EAX69159.1 - 0.082 12.9 2.1 0.16 12.0 0.0 2.4 2 1 0 2 2 2 0 L27_1 TMP PF05017.14 EAX69161.1 - 0.39 11.5 7.5 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69162.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX69163.1 - 9.2e-221 733.4 26.2 8.9e-219 726.8 26.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) TFIIA PF03153.13 EAX69163.1 - 0.57 10.1 10.7 0.76 9.7 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BA14K PF07886.11 EAX69163.1 - 1.7 8.6 4.1 58 3.7 1.4 3.4 1 1 2 3 3 3 0 BA14K-like protein DUF2362 PF10154.9 EAX69167.1 - 0.016 14.2 6.8 0.018 14.0 6.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) ChlamPMP_M PF07548.11 EAX69167.1 - 1.5 8.7 9.9 3 7.7 9.9 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain AMPKBI PF04739.15 EAX69167.1 - 2.1 8.7 21.7 12 6.3 0.5 4.1 2 2 1 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain AAA_22 PF13401.6 EAX69169.1 - 6.3e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69169.1 - 7e-05 22.9 2.6 0.00013 22.0 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69169.1 - 0.0004 20.2 0.0 0.00059 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69169.1 - 0.0009 19.1 0.9 0.0029 17.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69169.1 - 0.0074 16.6 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69169.1 - 0.035 13.8 0.3 0.92 9.2 0.0 2.4 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX69169.1 - 0.04 13.4 0.1 0.06 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69169.1 - 0.076 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69169.1 - 0.11 12.9 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69169.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_D5 PF03288.16 EAX69170.1 - 3.7e-05 24.1 2.6 0.00023 21.6 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Trypan_PARP PF05887.11 EAX69171.1 - 0.015 15.3 10.2 0.017 15.1 10.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_22 PF13401.6 EAX69172.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69172.1 - 8.2e-05 22.7 3.1 0.00015 21.8 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69172.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69172.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69172.1 - 0.003 17.3 0.3 0.3 10.8 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX69172.1 - 0.0077 16.6 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69172.1 - 0.048 13.1 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69172.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69172.1 - 0.093 13.2 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69172.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69172.1 - 0.2 11.9 4.6 4.1 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) PSP PF04046.16 EAX69173.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69174.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX69175.1 - 0.016 15.2 7.9 0.025 14.5 7.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69175.1 - 5.8 7.4 4.8 8.3 6.9 4.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4106 PF13388.6 EAX69176.1 - 5.4e-97 325.7 4.3 5.4e-97 325.7 4.3 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) DUF4678 PF15727.5 EAX69176.1 - 0.11 11.7 2.6 0.15 11.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) DUF4108 PF13390.6 EAX69179.1 - 3e-63 212.0 6.6 3.4e-63 211.8 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX69180.1 - 7.6e-05 22.8 3.6 0.00013 22.0 3.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX69180.1 - 0.00016 21.9 0.0 0.0009 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX69180.1 - 0.00036 20.3 0.0 0.00051 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69180.1 - 0.00074 19.4 1.0 0.0023 17.7 1.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69180.1 - 0.00095 18.9 0.2 0.098 12.4 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX69180.1 - 0.0085 16.4 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69180.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69180.1 - 0.074 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX69180.1 - 0.084 13.1 3.9 2.5 8.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA PF00004.29 EAX69180.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69180.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2897 PF11446.8 EAX69181.1 - 0.16 11.9 1.7 0.32 10.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX69182.1 - 3.3e-111 370.5 6.5 3.8e-111 370.3 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX69182.1 - 0.046 13.2 0.5 0.066 12.7 0.4 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX69182.1 - 0.24 12.0 2.0 0.51 11.0 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) PTR PF12789.7 EAX69183.1 - 5.7e-50 167.2 34.3 2.5e-30 104.3 14.6 3.1 3 1 1 4 4 4 2 Phage tail repeat like Amidase02_C PF12123.8 EAX69185.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX69186.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69186.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69186.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69186.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX69187.1 - 7.5e-24 83.6 8.8 7.5e-24 83.6 8.8 3.0 2 1 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX69187.1 - 0.011 15.5 0.2 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX69187.1 - 0.62 10.0 7.2 0.72 9.8 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) Pox_D5 PF03288.16 EAX69188.1 - 6.7e-06 26.5 3.0 3.7e-05 24.1 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX69188.1 - 0.021 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX69188.1 - 0.059 13.3 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX69189.1 - 6.6e-05 23.5 0.2 9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX69189.1 - 0.00073 20.0 2.0 0.0011 19.4 2.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX69189.1 - 0.013 15.5 1.3 0.018 15.0 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DNA_pol_B_2 PF03175.13 EAX69190.1 - 2.9e-16 59.4 4.2 5e-16 58.6 4.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69190.1 - 0.016 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX69190.1 - 0.041 13.9 1.4 0.84 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Big_7 PF17957.1 EAX69191.1 - 5.6e-06 27.0 4.5 0.0011 19.7 0.4 3.2 3 0 0 3 3 3 2 Bacterial Ig domain DUF4625 PF15418.6 EAX69191.1 - 0.0049 17.1 10.2 0.32 11.2 3.1 3.7 1 1 2 3 3 3 2 Domain of unknown function (DUF4625) DUF2326 PF10088.9 EAX69191.1 - 0.0056 16.4 5.7 0.45 10.2 0.2 3.1 1 1 2 3 3 3 2 Uncharacterised protein conserved in bacteria (DUF2326) DUF4832 PF16116.5 EAX69191.1 - 0.016 15.0 0.1 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4832) Inovirus_Gp2 PF11726.8 EAX69191.1 - 0.028 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Inovirus Gp2 Alph_Pro_TM PF09608.10 EAX69191.1 - 0.12 12.2 0.0 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) UCH PF00443.29 EAX69193.1 - 1.9e-11 44.0 1.7 5.2e-10 39.3 1.7 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX69193.1 - 2.7e-05 24.0 3.0 0.00091 18.9 0.2 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX69193.1 - 0.0012 18.4 2.4 0.36 10.2 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_S64 PF08192.11 EAX69193.1 - 0.0074 14.8 1.3 0.05 12.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S64 Fungal_lectin_2 PF18647.1 EAX69193.1 - 0.067 13.6 0.4 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin PSP PF04046.16 EAX69194.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX69195.1 - 7.8e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PWI PF01480.17 EAX69196.1 - 0.032 14.6 0.1 0.048 14.0 0.1 1.2 1 0 0 1 1 1 0 PWI domain Pox_A32 PF04665.12 EAX69197.1 - 8.2e-08 32.0 1.3 1e-07 31.7 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69197.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69197.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69197.1 - 0.048 13.6 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DNA_pol_B_2 PF03175.13 EAX69198.1 - 1.5e-15 57.1 2.1 1.7e-15 56.9 2.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_4 PF13637.6 EAX69199.1 - 7.3e-14 51.9 0.3 1.6e-06 28.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX69199.1 - 1.9e-13 50.8 0.3 1.5e-12 47.9 0.3 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX69199.1 - 1.6e-09 37.7 0.1 5.7e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX69199.1 - 2.2e-09 36.8 0.1 3.8e-06 26.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX69199.1 - 7.8e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4107 PF13389.6 EAX69200.1 - 4e-72 241.7 3.9 5.2e-72 241.3 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX69200.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Mito_fiss_reg PF05308.11 EAX69202.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69202.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Trypan_PARP PF05887.11 EAX69203.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX69204.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69204.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_4 PF13637.6 EAX69207.1 - 5.9e-34 116.0 3.3 4.8e-10 39.8 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX69207.1 - 1e-33 115.8 1.1 2e-13 50.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX69207.1 - 1e-30 105.4 0.2 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69207.1 - 5.3e-26 87.8 0.9 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX69207.1 - 1.1e-21 76.3 5.2 0.00026 21.3 0.0 6.7 6 1 1 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX69207.1 - 0.0025 17.7 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX69207.1 - 0.063 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase DUF1493 PF07377.12 EAX69209.1 - 0.046 14.2 0.5 0.094 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Gly-zipper_Omp PF13488.6 EAX69210.1 - 0.0056 16.7 9.1 0.008 16.2 9.1 1.2 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX69210.1 - 0.23 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX69210.1 - 0.89 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX69212.1 - 7.8e-46 154.0 34.4 1.1e-27 95.8 18.3 4.5 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX69212.1 - 0.02 14.6 1.1 0.041 13.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX69212.1 - 0.16 12.3 3.1 2.3 8.6 0.3 3.0 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain PTR PF12789.7 EAX69213.1 - 5.6e-40 135.2 27.1 1.4e-32 111.5 13.7 4.7 4 2 1 5 5 5 2 Phage tail repeat like ANAPC4_WD40 PF12894.7 EAX69214.1 - 0.00016 21.9 0.1 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3839 PF12943.7 EAX69215.1 - 8.2e-17 61.5 3.3 1.3e-16 60.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX69217.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69217.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69217.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69217.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX69218.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX69219.1 - 0.048 13.4 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DNA_pol_B_2 PF03175.13 EAX69220.1 - 1.5e-20 73.6 4.9 1.5e-20 73.6 4.9 1.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAX69221.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69221.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX69222.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69222.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4108 PF13390.6 EAX69224.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX69226.1 - 1.8e-134 446.7 15.9 2.3e-134 446.4 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX69226.1 - 0.0089 15.3 0.2 0.044 13.0 0.2 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region KELK PF15796.5 EAX69226.1 - 0.11 13.0 4.9 1.3 9.5 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX69226.1 - 0.77 10.3 5.3 0.3 11.7 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX69226.1 - 1 9.7 4.1 1.3 9.3 1.3 2.5 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit MetW PF07021.12 EAX69227.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DNA_pol_B_2 PF03175.13 EAX69229.1 - 9.4e-29 100.6 7.0 1.6e-28 99.8 7.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX69230.1 - 5.5e-25 87.4 0.1 6.1e-25 87.3 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX69231.1 - 1.2e-34 118.5 1.6 1.4e-34 118.3 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain IKKbetaNEMObind PF12179.8 EAX69232.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PSP PF04046.16 EAX69233.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69234.1 - 0.027 15.0 2.7 11 7.2 0.2 2.9 3 0 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX69235.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69235.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69235.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX69236.1 - 5.7e-23 81.5 9.8 2.3e-22 79.5 9.8 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69236.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX69237.1 - 3e-22 78.4 16.2 6.1e-17 61.4 1.8 3.9 4 1 0 4 4 4 2 Phage tail repeat like RNA_lig_T4_1 PF09511.10 EAX69237.1 - 0.027 14.3 1.3 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 RNA ligase DUF4116 PF13475.6 EAX69237.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX69237.1 - 0.053 13.4 3.4 1.2 9.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DNA_pol_B_2 PF03175.13 EAX69238.1 - 1.2e-09 37.6 2.4 1.3e-08 34.2 2.4 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX69238.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX69238.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF4106 PF13388.6 EAX69239.1 - 2.1e-175 584.0 32.5 8e-175 582.1 32.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX69239.1 - 0.19 11.5 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3801 PF12687.7 EAX69239.1 - 1.2 9.2 10.0 3.5 7.7 10.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) DNA_pol_B_2 PF03175.13 EAX69240.1 - 8e-12 44.8 0.2 1.6e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69240.1 - 0.0066 15.8 0.2 0.0095 15.3 0.2 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein Pox_A32 PF04665.12 EAX69243.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69243.1 - 2.8e-05 24.4 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69243.1 - 5e-05 23.1 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69243.1 - 0.00015 21.8 3.1 0.00032 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69243.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69243.1 - 0.0012 18.7 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69243.1 - 0.0018 17.9 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69243.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX69243.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX69243.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69243.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69243.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69243.1 - 0.3 11.4 3.7 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Trypan_PARP PF05887.11 EAX69244.1 - 0.0084 16.1 8.5 0.012 15.6 8.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX69245.1 - 6.3e-72 241.0 3.5 8.7e-72 240.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Chromo PF00385.24 EAX69246.1 - 0.084 12.8 7.2 0.042 13.8 4.6 1.9 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain MgsA_C PF12002.8 EAX69246.1 - 0.12 12.4 0.4 0.13 12.1 0.4 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal KilA-N PF04383.13 EAX69247.1 - 4.1e-40 136.1 0.1 9.1e-40 135.0 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX69247.1 - 0.0035 17.9 0.1 0.01 16.4 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DUF2939 PF11159.8 EAX69248.1 - 0.016 15.6 0.7 0.02 15.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69248.1 - 2.3 7.1 4.9 2.3 7.2 4.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX69248.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69249.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX69250.1 - 1.6e-22 80.1 4.3 2e-22 79.7 4.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69250.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) KilA-N PF04383.13 EAX69251.1 - 6.6e-23 80.7 0.3 1.2e-22 79.9 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX69251.1 - 0.048 13.6 0.8 0.14 12.1 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMP PF05017.14 EAX69252.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX69254.1 - 4.1e-142 471.7 17.8 5.4e-142 471.4 17.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69254.1 - 0.047 14.1 1.1 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 Fez1 HAUS4 PF14735.6 EAX69254.1 - 0.19 11.4 6.1 1.9 8.1 1.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Rx_N PF18052.1 EAX69254.1 - 0.25 11.7 6.1 0.71 10.2 0.0 3.4 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX69254.1 - 1.1 9.8 5.0 1.8 9.0 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX69255.1 - 2.9e-32 112.5 19.6 4.5e-32 111.9 19.6 1.3 1 1 0 1 1 1 1 Glycine rich protein Ank_2 PF12796.7 EAX69256.1 - 1.3e-57 192.3 27.3 7.4e-14 52.1 1.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX69256.1 - 1.7e-57 189.5 22.1 6.8e-08 32.6 0.1 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX69256.1 - 2.5e-56 187.4 17.6 2e-12 47.3 0.1 8.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69256.1 - 1.3e-46 151.2 20.1 9.5e-05 22.5 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EAX69256.1 - 5.7e-46 154.0 15.2 6.6e-11 42.2 0.2 6.4 3 3 3 6 6 6 6 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX69256.1 - 0.011 15.9 4.3 7.7 6.8 0.2 4.9 4 2 1 5 5 5 0 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX69256.1 - 0.05 13.9 0.7 6.2 7.2 0.0 3.7 1 1 3 4 4 4 0 Pleckstrin homology domain DUF445 PF04286.12 EAX69257.1 - 0.19 11.5 3.6 0.28 11.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UPF0253 PF06786.12 EAX69257.1 - 0.21 11.9 0.2 0.21 11.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) DUF3417 PF11897.8 EAX69257.1 - 0.23 11.9 4.1 0.25 11.8 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3417) Tho2 PF11262.8 EAX69259.1 - 0.061 12.5 2.7 0.068 12.4 2.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TPR_22 PF18833.1 EAX69259.1 - 0.064 13.4 0.6 0.18 12.0 0.1 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Spo12 PF05032.12 EAX69259.1 - 0.11 12.4 2.2 0.11 12.4 2.2 2.6 4 0 0 4 4 4 0 Spo12 family DUF4108 PF13390.6 EAX69261.1 - 2.2e-61 205.9 5.2 2.5e-61 205.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX69261.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_D5 PF03288.16 EAX69262.1 - 1.5e-06 28.6 2.4 1.6e-05 25.3 2.4 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX69262.1 - 0.0027 18.3 0.1 0.0055 17.3 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX69262.1 - 0.0094 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain T5orf172 PF10544.9 EAX69263.1 - 3.4e-06 27.5 0.2 6.8e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain ATP-synt_F6 PF05511.11 EAX69263.1 - 0.11 12.9 0.6 21 5.6 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 PapD_N PF00345.20 EAX69264.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69264.1 - 0.044 13.8 0.8 0.065 13.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) GAGA_bind PF06217.12 EAX69265.1 - 0.085 13.1 4.6 0.1 12.8 4.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX69265.1 - 6.8 6.7 8.0 16 5.5 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX69266.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69266.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF641 PF04859.12 EAX69267.1 - 0.04 14.2 2.1 0.062 13.6 2.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX69267.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor DUF3839 PF12943.7 EAX69268.1 - 4e-80 268.8 11.1 5.3e-80 268.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX69268.1 - 0.087 12.3 0.5 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 DUF2939 PF11159.8 EAX69269.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX69269.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69270.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX69271.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX69271.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DDE_Tnp_4 PF13359.6 EAX69273.1 - 2e-19 69.8 0.0 6.3e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX69273.1 - 1.4e-09 37.9 0.2 5.8e-09 35.8 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX69273.1 - 0.00017 21.3 0.1 0.0021 17.7 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX69273.1 - 0.11 11.9 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Amidase02_C PF12123.8 EAX69274.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX69275.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Mito_fiss_reg PF05308.11 EAX69277.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69277.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMP PF05017.14 EAX69278.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX69278.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX69279.1 - 0.11 12.3 0.8 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2939 PF11159.8 EAX69281.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69281.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX69281.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF3839 PF12943.7 EAX69282.1 - 1.9e-157 521.9 14.7 2.4e-157 521.6 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69282.1 - 0.11 13.0 4.0 0.55 10.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX69282.1 - 0.29 11.6 6.5 2.2 8.8 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX69283.1 - 8e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX69285.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69285.1 - 0.08 12.9 0.4 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX69286.1 - 1.3e-07 31.4 1.1 7.4e-07 28.9 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein TK PF00265.18 EAX69286.1 - 0.099 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX69286.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTR PF12789.7 EAX69287.1 - 4.3e-12 45.9 0.7 4.3e-12 45.9 0.7 3.3 2 1 0 2 2 2 1 Phage tail repeat like DUF1493 PF07377.12 EAX69288.1 - 0.045 14.2 1.3 0.068 13.6 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PRD PF00874.20 EAX69289.1 - 0.047 14.0 4.5 1.7 9.0 0.6 2.1 1 1 1 2 2 2 0 PRD domain DUF4108 PF13390.6 EAX69291.1 - 2.1e-61 206.0 8.3 2.4e-61 205.9 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX69292.1 - 1.2e-06 28.4 1.3 1.3e-06 28.2 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain ComA PF02679.15 EAX69292.1 - 0.036 13.5 0.9 0.041 13.3 0.9 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Pox_D5 PF03288.16 EAX69295.1 - 2.1e-05 24.9 2.2 0.00013 22.4 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PTR PF12789.7 EAX69296.1 - 8.9e-06 25.7 7.9 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 2 Phage tail repeat like Phage_fiber PF03335.13 EAX69296.1 - 0.11 12.7 0.6 0.11 12.7 0.6 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX69296.1 - 0.9 10.1 3.9 5.9 7.5 1.9 2.7 2 1 0 2 2 2 0 YmaF family PSP PF04046.16 EAX69297.1 - 0.068 13.1 0.8 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69298.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX69299.1 - 2.5e-38 131.8 1.1 2.9e-38 131.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX69301.1 - 1.4e-116 388.1 5.9 1.7e-116 387.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX69302.1 - 8.2e-07 28.7 2.3 8.2e-07 28.7 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69302.1 - 3e-05 24.3 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69302.1 - 4.1e-05 23.4 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69302.1 - 0.00012 22.1 2.9 0.00029 20.9 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69302.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX69302.1 - 0.0018 17.9 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX69302.1 - 0.0018 18.1 0.8 0.0051 16.6 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69302.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69302.1 - 0.068 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX69302.1 - 0.079 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX69302.1 - 0.086 13.3 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69302.1 - 0.09 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69302.1 - 0.31 11.3 4.0 8.9 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX69303.1 - 8.8e-22 77.6 6.1 1.1e-21 77.2 6.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF846 PF05832.12 EAX69304.1 - 0.045 13.8 0.1 0.09 12.8 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DNA_pol_B_2 PF03175.13 EAX69305.1 - 6.3e-13 48.4 2.0 1.1e-12 47.6 2.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69305.1 - 0.056 12.7 0.1 0.08 12.2 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4106 PF13388.6 EAX69306.1 - 1.6e-207 689.8 17.4 1.8e-207 689.6 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) FAS_N PF17828.1 EAX69307.1 - 0.0044 17.0 0.2 0.0056 16.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta FAS_N PF17828.1 EAX69308.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Gly_rich PF12810.7 EAX69309.1 - 9.4e-42 143.6 27.6 1.1e-41 143.4 27.6 1.1 1 0 0 1 1 1 1 Glycine rich protein PTR PF12789.7 EAX69310.1 - 4.4e-06 26.7 1.1 4.4e-06 26.7 1.1 3.5 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX69310.1 - 0.0064 16.1 2.9 0.096 12.3 2.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Kinetochor_Ybp2 PF08568.10 EAX69310.1 - 0.068 11.7 0.0 0.083 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin DDE_3 PF13358.6 EAX69310.1 - 0.079 12.7 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease YmaF PF12788.7 EAX69310.1 - 0.18 12.3 2.8 2.1 8.9 1.3 2.8 2 1 0 2 2 2 0 YmaF family Amidase02_C PF12123.8 EAX69311.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69311.1 - 0.21 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX69312.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX69313.1 - 0.67 9.9 4.5 1.3 9.0 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX69314.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69314.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69314.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69314.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Amidase02_C PF12123.8 EAX69315.1 - 0.0079 15.9 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69315.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TMP PF05017.14 EAX69317.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat EpuA PF11772.8 EAX69318.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Mito_fiss_reg PF05308.11 EAX69319.1 - 0.1 12.7 0.5 0.11 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69319.1 - 0.73 9.3 2.6 0.72 9.3 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4108 PF13390.6 EAX69320.1 - 3.9e-58 195.4 4.5 4.5e-58 195.2 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX69322.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69323.1 - 0.042 14.4 4.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Antimicrobial_7 PF08102.11 EAX69323.1 - 0.055 13.7 0.4 0.088 13.0 0.4 1.3 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Y_phosphatase2 PF03162.13 EAX69324.1 - 0.0047 16.5 0.3 0.0079 15.8 0.3 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX69324.1 - 0.013 15.5 0.4 0.046 13.7 0.0 1.9 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX69324.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAX69326.1 - 9.5e-80 267.5 12.3 1.2e-79 267.2 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX69327.1 - 5.3e-05 22.8 3.2 7.7e-05 22.3 3.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69327.1 - 0.004 17.2 0.1 0.0094 16.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69327.1 - 0.017 14.7 0.2 0.034 13.7 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX69327.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PSP PF04046.16 EAX69328.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69329.1 - 0.14 12.8 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX69330.1 - 1.2e-10 41.3 0.1 2.1e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain MtrG PF04210.13 EAX69330.1 - 0.17 11.8 0.3 0.4 10.6 0.3 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Amidase02_C PF12123.8 EAX69331.1 - 0.00074 19.2 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX69332.1 - 3.6e-09 36.0 1.0 6.1e-09 35.3 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69332.1 - 0.1 12.6 0.0 0.82 9.7 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX69334.1 - 1.4e-34 118.3 0.6 2.8e-34 117.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69334.1 - 0.02 15.5 0.0 0.064 13.9 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family PAS_7 PF12860.7 EAX69334.1 - 0.1 12.7 1.5 0.62 10.2 0.2 2.2 2 0 0 2 2 2 0 PAS fold DUF3839 PF12943.7 EAX69335.1 - 1.4e-80 270.3 10.3 1.7e-80 269.9 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX69335.1 - 0.14 12.0 0.9 0.47 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3896 PF13035.6 EAX69336.1 - 0.21 11.8 1.6 7.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) WRKY PF03106.15 EAX69337.1 - 0.024 14.9 0.8 0.024 14.9 0.8 2.7 2 2 1 3 3 3 0 WRKY DNA -binding domain DUF4107 PF13389.6 EAX69338.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX69339.1 - 0.22 12.3 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX69341.1 - 3.6e-43 146.0 0.1 4.8e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Amidase02_C PF12123.8 EAX69342.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Annexin PF00191.20 EAX69343.1 - 0.13 12.4 0.3 0.54 10.4 0.2 2.1 1 1 1 2 2 2 0 Annexin FliD_N PF02465.18 EAX69345.1 - 0.18 12.5 5.5 0.24 12.1 5.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX69345.1 - 1 8.1 4.3 1.3 7.8 4.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HC2 PF07382.11 EAX69346.1 - 1.3e-07 31.9 12.4 1.5e-07 31.7 12.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX69346.1 - 4.2e-05 23.6 0.5 5.1e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Aurora-A_bind PF09041.10 EAX69346.1 - 0.96 9.6 8.7 2.3e+02 1.9 8.7 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX69346.1 - 1.8 8.6 5.1 71 3.5 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) DNA_pol_B_2 PF03175.13 EAX69348.1 - 7.9e-25 87.6 8.3 3.4e-24 85.5 8.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69348.1 - 0.075 13.0 0.0 0.88 9.6 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor Pox_A32 PF04665.12 EAX69349.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69349.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69349.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69349.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69349.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69349.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69349.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69349.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69349.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69349.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69349.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69349.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX69350.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69350.1 - 0.16 11.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX69352.1 - 8.8e-14 51.2 8.3 1e-13 51.0 4.4 2.0 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral PhaP_Bmeg PF09602.10 EAX69352.1 - 0.084 12.8 0.1 0.79 9.6 0.1 2.2 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PHM7_cyt PF14703.6 EAX69352.1 - 0.11 12.8 0.2 0.31 11.3 0.1 2.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF5106 PF17127.4 EAX69352.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Isy1 PF06246.12 EAX69352.1 - 0.12 11.9 0.6 0.24 11.0 0.6 1.5 1 1 0 1 1 1 0 Isy1-like splicing family DUF5365 PF17326.2 EAX69353.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX69353.1 - 0.031 14.6 0.5 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 PWI domain TMP PF05017.14 EAX69354.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX69354.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX69355.1 - 0.1 13.1 0.6 0.24 11.9 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX69356.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX69357.1 - 7.1e-21 74.6 3.7 1e-20 74.1 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX69359.1 - 3.7e-41 139.5 1.0 7e-41 138.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF4106 PF13388.6 EAX69360.1 - 3.4e-195 649.2 21.4 3.9e-195 649.0 21.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX69360.1 - 0.049 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Ndc1_Nup PF09531.10 EAX69360.1 - 7.7 5.1 6.5 12 4.4 6.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMP PF05017.14 EAX69361.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69362.1 - 0.061 13.2 0.6 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX69363.1 - 0.02 15.4 1.5 0.027 14.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX69364.1 - 3.1e-09 36.7 0.3 3.1e-09 36.7 0.3 3.0 3 1 0 3 3 3 1 Phage tail repeat like IstB_IS21 PF01695.17 EAX69365.1 - 2.6e-05 24.0 0.3 0.35 10.6 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69365.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69365.1 - 0.00029 20.9 4.8 0.00039 20.5 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX69365.1 - 0.00031 20.3 2.2 0.00031 20.3 2.2 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX69365.1 - 0.00072 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX69365.1 - 0.0024 17.5 3.0 0.0083 15.8 0.5 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX69365.1 - 0.0054 16.6 2.6 0.0082 16.0 1.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69365.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69365.1 - 0.046 14.1 0.1 0.44 11.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX69365.1 - 0.059 13.4 0.8 0.91 9.6 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX69365.1 - 0.059 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX69365.1 - 0.088 12.2 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69365.1 - 1 9.6 6.2 7.9 6.8 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX69365.1 - 2.6 8.8 11.6 0.26 12.0 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 APG12 PF04110.13 EAX69365.1 - 4.9 7.6 7.0 0.54 10.7 1.1 2.4 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 JMY PF15871.5 EAX69366.1 - 0.019 14.3 0.8 0.025 13.9 0.8 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX69367.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4106 PF13388.6 EAX69368.1 - 1.5e-91 307.7 5.2 1.5e-91 307.7 5.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KilA-N PF04383.13 EAX69369.1 - 4.2e-40 136.1 0.2 1e-39 134.9 0.2 1.7 1 1 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX69369.1 - 0.0056 17.3 0.1 0.017 15.8 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family CD99L2 PF12301.8 EAX69370.1 - 0.074 13.3 0.6 0.14 12.4 0.1 1.7 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF347 PF03988.12 EAX69370.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pox_A32 PF04665.12 EAX69371.1 - 1.9e-05 24.2 2.4 1.9e-05 24.2 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69371.1 - 2.1e-05 24.8 0.2 0.00016 22.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69371.1 - 3.7e-05 23.5 0.2 0.29 10.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69371.1 - 9.5e-05 22.5 2.7 0.0002 21.4 2.7 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69371.1 - 0.00046 20.0 0.1 0.00086 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69371.1 - 0.0012 18.7 0.6 0.0035 17.2 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69371.1 - 0.0016 18.1 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69371.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX69371.1 - 0.055 13.0 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX69371.1 - 0.057 12.9 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX69371.1 - 0.067 13.6 0.1 0.6 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69371.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX69371.1 - 0.11 12.5 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX69371.1 - 0.31 11.3 4.1 9 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX69373.1 - 0.15 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX69374.1 - 5.4e-05 23.3 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX69374.1 - 6.3e-05 23.3 0.0 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX69374.1 - 0.00044 20.1 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69374.1 - 0.00072 19.4 0.7 0.0021 17.9 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69374.1 - 0.0044 16.8 0.3 0.26 11.0 0.0 2.6 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX69374.1 - 0.0077 16.6 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69374.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69374.1 - 0.083 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69374.1 - 0.1 13.0 0.1 0.38 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69374.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69374.1 - 0.24 11.6 4.5 5.3 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX69376.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69376.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69376.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69376.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX69377.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69377.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69377.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69377.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69377.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX69377.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX69377.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Ank_4 PF13637.6 EAX69378.1 - 9.4e-18 64.4 0.9 5.1e-11 42.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX69378.1 - 9.5e-12 45.4 0.2 1.8e-11 44.4 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX69378.1 - 4.9e-09 36.3 0.1 3.2e-08 33.7 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69378.1 - 1.4e-08 34.3 0.6 0.0054 17.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX69378.1 - 3.9e-08 33.4 1.3 0.031 14.7 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF3839 PF12943.7 EAX69379.1 - 3.3e-97 324.7 6.8 3.7e-97 324.5 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX69379.1 - 0.034 13.7 0.3 0.037 13.5 0.3 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX69379.1 - 0.28 11.8 2.4 0.39 11.4 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX69380.1 - 5.3e-156 517.2 15.5 6.1e-156 517.0 15.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX69380.1 - 0.13 12.7 0.5 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Glu-tRNAGln PF02686.15 EAX69380.1 - 0.3 11.4 1.5 0.79 10.1 0.5 2.1 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX69380.1 - 0.45 11.1 5.1 0.72 10.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX69380.1 - 0.78 10.2 8.3 2.5 8.6 1.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDE_1 PF03184.19 EAX69382.1 - 1.4e-16 60.6 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Imm70 PF15601.6 EAX69383.1 - 0.19 11.3 5.0 15 5.1 0.1 3.1 1 1 2 3 3 3 0 Immunity protein 70 AAA_22 PF13401.6 EAX69384.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69384.1 - 6.9e-05 22.6 0.3 0.25 11.1 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69384.1 - 7.6e-05 22.8 2.9 0.00013 22.0 2.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69384.1 - 0.0004 20.2 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69384.1 - 0.0011 18.8 1.0 0.0043 16.9 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69384.1 - 0.0088 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69384.1 - 0.056 12.9 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX69384.1 - 0.072 13.5 0.1 0.42 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX69384.1 - 0.078 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX69384.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69384.1 - 0.29 11.4 4.7 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX69385.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69385.1 - 0.21 11.4 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PTR PF12789.7 EAX69387.1 - 9.6e-10 38.4 7.7 1.1e-08 35.0 0.4 4.1 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX69387.1 - 0.065 12.8 9.2 0.05 13.2 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX69387.1 - 1.5 9.0 6.5 0.45 10.6 0.9 2.4 2 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) DUF4107 PF13389.6 EAX69388.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) YbaJ PF10757.9 EAX69390.1 - 0.064 13.8 0.7 2.5 8.7 0.1 2.3 1 1 1 2 2 2 0 Biofilm formation regulator YbaJ DUF1367 PF07105.11 EAX69390.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) TraG_N PF07916.11 EAX69390.1 - 0.17 10.7 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3592 PF12158.8 EAX69391.1 - 0.21 11.7 2.9 0.41 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) HbrB PF08539.11 EAX69391.1 - 4.4 7.3 8.0 0.56 10.2 3.1 1.8 1 1 1 2 2 2 0 HbrB-like DUF2939 PF11159.8 EAX69392.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69392.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX69392.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69393.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF846 PF05832.12 EAX69394.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF1493 PF07377.12 EAX69395.1 - 0.08 13.4 0.8 0.22 12.0 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF5528 PF17666.1 EAX69396.1 - 0.068 13.1 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5528) Mito_fiss_reg PF05308.11 EAX69396.1 - 0.14 12.2 0.5 0.15 12.1 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69396.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PTR PF12789.7 EAX69397.1 - 2.7e-05 24.2 0.6 2.7e-05 24.2 0.6 4.0 3 2 0 3 3 3 1 Phage tail repeat like EDR1 PF14381.6 EAX69397.1 - 0.032 13.9 0.2 2.4 7.9 0.1 2.4 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF445 PF04286.12 EAX69397.1 - 0.057 13.2 8.8 0.13 12.0 8.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX69397.1 - 0.084 13.3 2.2 0.16 12.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX69397.1 - 0.13 11.2 0.7 0.22 10.5 0.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4795 PF16043.5 EAX69397.1 - 1.7 8.2 17.1 2.8e+02 1.0 17.0 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PKcGMP_CC PF16808.5 EAX69397.1 - 4.9 7.1 7.2 2.7 7.9 0.3 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase T5orf172 PF10544.9 EAX69398.1 - 0.00096 19.7 0.3 0.0021 18.6 0.3 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX69398.1 - 0.092 12.3 0.2 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 Legume lectin domain GPS2_interact PF15784.5 EAX69399.1 - 0.032 14.7 0.4 0.041 14.3 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX69400.1 - 0.034 14.1 10.7 0.04 13.9 10.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69400.1 - 7.7 7.0 7.8 9.7 6.6 7.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_D5 PF03288.16 EAX69401.1 - 3.2e-05 24.3 3.5 0.00018 22.0 3.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX69401.1 - 0.026 15.1 0.1 0.051 14.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX69401.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX69402.1 - 1.1e-57 194.0 4.1 1.2e-57 193.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) zf-C2H2_assoc2 PF16624.5 EAX69403.1 - 0.016 16.2 3.3 0.02 15.9 3.1 1.3 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger SLC12 PF03522.15 EAX69403.1 - 0.016 14.2 0.4 0.019 14.0 0.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NEMP PF10225.9 EAX69403.1 - 0.67 9.6 1.5 0.76 9.4 1.5 1.1 1 0 0 1 1 1 0 NEMP family DDE_Tnp_ISL3 PF01610.17 EAX69404.1 - 7.8e-06 25.8 0.0 9.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Transposase DUF4107 PF13389.6 EAX69405.1 - 6.9e-25 88.1 2.4 7.9e-25 87.9 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX69407.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TPR_MLP1_2 PF07926.12 EAX69408.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX69408.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX69408.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF2939 PF11159.8 EAX69410.1 - 0.016 15.6 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX69410.1 - 3.2 8.4 6.3 7.6 7.2 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69411.1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX69411.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal MULE PF10551.9 EAX69412.1 - 1.1e-11 45.0 0.1 1.9e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF4107 PF13389.6 EAX69413.1 - 5.1e-73 244.6 3.7 6.7e-73 244.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF563 PF04577.14 EAX69414.1 - 3.5e-31 109.0 0.6 4.9e-31 108.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Amidase02_C PF12123.8 EAX69415.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69415.1 - 0.17 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX69416.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69416.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69416.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69416.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69416.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69416.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69416.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69416.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69416.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69416.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69416.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69416.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69417.1 - 6.7e-157 520.1 14.2 8.4e-157 519.8 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69417.1 - 0.044 14.3 0.6 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX69417.1 - 0.11 12.1 0.1 0.41 10.1 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX69417.1 - 0.29 11.0 1.7 0.77 9.6 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX69417.1 - 0.53 10.6 2.9 2.9 8.2 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX69417.1 - 0.71 10.4 5.5 4.8 7.7 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX69418.1 - 4.1e-54 182.4 5.7 4.6e-54 182.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX69419.1 - 1.4e-13 51.0 0.1 2.6e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain PdaC PF13739.6 EAX69419.1 - 0.16 13.0 0.8 0.41 11.7 0.8 1.7 1 0 0 1 1 1 0 Deacetylase PdaC Trypan_PARP PF05887.11 EAX69420.1 - 0.022 14.8 10.4 0.03 14.3 10.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX69421.1 - 4.1e-59 198.6 8.2 4.5e-59 198.5 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX69422.1 - 9.1e-22 77.6 5.2 1.2e-21 77.2 5.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX69423.1 - 6.7e-64 215.7 3.0 8.1e-64 215.4 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX69423.1 - 0.024 14.1 0.3 0.027 14.0 0.3 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX69423.1 - 0.21 12.2 1.4 2.1 9.0 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Pox_A32 PF04665.12 EAX69425.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69425.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69425.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69425.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69425.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX69425.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX69425.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Peptidase_S8 PF00082.22 EAX69426.1 - 1.3e-05 24.7 6.4 0.00022 20.6 6.4 2.2 1 1 0 1 1 1 1 Subtilase family Amidase02_C PF12123.8 EAX69427.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PI3K_p85B PF02192.16 EAX69429.1 - 0.12 12.1 0.2 3.7 7.3 0.1 2.1 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain PSP PF04046.16 EAX69430.1 - 0.065 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69431.1 - 0.088 13.4 5.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PapD_N PF00345.20 EAX69432.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69432.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX69433.1 - 3.4e-10 39.4 2.3 2.1e-09 36.8 2.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69433.1 - 0.11 12.4 0.0 0.84 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Ank_2 PF12796.7 EAX69434.1 - 3.5e-33 114.0 0.3 1.9e-14 54.0 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX69434.1 - 1.3e-25 88.7 0.1 8.8e-06 25.9 0.0 5.3 6 0 0 6 6 5 4 Ankyrin repeat Ank_4 PF13637.6 EAX69434.1 - 1.7e-24 85.8 0.0 2.7e-09 37.4 0.0 3.8 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX69434.1 - 8.8e-23 80.1 0.1 3.7e-09 36.7 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69434.1 - 2.1e-21 73.7 0.0 0.00053 20.2 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Wtap PF17098.5 EAX69434.1 - 0.0004 20.3 2.6 0.00067 19.6 2.6 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family APG6_N PF17675.1 EAX69434.1 - 0.0016 19.0 10.6 0.003 18.1 10.6 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 EAX69434.1 - 0.0016 17.1 6.3 0.0016 17.1 6.3 1.9 2 1 1 3 3 3 1 Flagellar Assembly Protein A Spc7 PF08317.11 EAX69434.1 - 0.0044 16.0 8.6 0.0058 15.5 8.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein GBP_C PF02841.14 EAX69434.1 - 0.0074 15.7 6.4 0.01 15.3 6.4 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ATG16 PF08614.11 EAX69434.1 - 0.0097 16.1 6.8 0.015 15.6 6.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FliJ PF02050.16 EAX69434.1 - 0.019 15.2 5.5 0.05 13.8 5.5 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 EAX69434.1 - 0.02 14.4 3.0 0.027 14.1 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TerB_C PF15615.6 EAX69434.1 - 0.021 15.2 3.6 0.048 13.9 3.5 1.7 2 0 0 2 2 1 0 TerB-C domain DUF2203 PF09969.9 EAX69434.1 - 0.027 15.2 4.1 0.055 14.2 3.8 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Golgin_A5 PF09787.9 EAX69434.1 - 0.027 13.9 10.9 0.038 13.5 10.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ABC_tran_CTD PF16326.5 EAX69434.1 - 0.029 14.6 6.9 0.071 13.4 6.9 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Het-C PF07217.11 EAX69434.1 - 0.03 12.9 3.5 0.041 12.4 3.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C OmpH PF03938.14 EAX69434.1 - 0.031 14.6 9.7 0.048 14.0 9.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) L_protein_N PF15518.6 EAX69434.1 - 0.042 13.7 0.0 6.1 6.8 0.0 2.9 2 1 1 3 3 3 0 L protein N-terminus WXG100 PF06013.12 EAX69434.1 - 0.06 13.6 3.9 0.21 11.8 2.9 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Allexi_40kDa PF05549.11 EAX69434.1 - 0.078 12.5 4.0 0.12 11.8 4.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMF_TATA_bd PF12325.8 EAX69434.1 - 0.11 12.8 11.9 0.18 12.0 8.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAX69434.1 - 0.13 11.5 1.1 0.19 11.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EAX69434.1 - 0.17 12.0 7.4 0.088 12.9 3.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 EAX69434.1 - 0.18 9.7 6.1 0.22 9.4 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACCA PF03255.14 EAX69434.1 - 0.2 11.6 3.8 0.48 10.3 3.8 1.7 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GIT1_C PF12205.8 EAX69434.1 - 0.3 11.2 6.6 0.43 10.7 5.9 1.6 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Prefoldin PF02996.17 EAX69434.1 - 0.31 11.0 15.0 0.32 10.9 5.8 3.7 1 1 2 3 3 3 0 Prefoldin subunit Lectin_N PF03954.14 EAX69434.1 - 0.33 10.7 5.0 0.61 9.8 5.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 EAX69434.1 - 0.5 9.4 9.5 0.66 9.0 9.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 EAX69434.1 - 0.51 11.1 8.7 1.3 9.8 5.5 2.4 1 1 1 2 2 2 0 Occludin homology domain DUF2730 PF10805.8 EAX69434.1 - 0.53 10.4 5.0 1.1 9.4 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 EAX69434.1 - 0.6 10.2 8.1 2.8 8.0 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 EAX69434.1 - 0.63 10.2 13.7 0.22 11.6 8.0 2.4 1 1 1 2 2 2 0 Swi5 DUF1640 PF07798.11 EAX69434.1 - 0.65 10.0 9.7 1 9.3 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc24 PF08286.11 EAX69434.1 - 0.79 10.0 14.4 0.33 11.2 8.6 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Muted PF14942.6 EAX69434.1 - 0.96 9.8 14.6 1.4 9.3 13.3 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF349 PF03993.12 EAX69434.1 - 1.1 9.6 6.7 7 7.0 3.6 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF948 PF06103.11 EAX69434.1 - 1.1 9.5 5.9 1.3 9.3 2.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EAX69434.1 - 1.3 9.5 9.5 5.4 7.5 7.9 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Cytochrom_B562 PF07361.11 EAX69434.1 - 1.3 9.7 8.2 5.2 7.8 2.5 3.0 1 1 2 3 3 3 0 Cytochrome b562 Rx_N PF18052.1 EAX69434.1 - 1.3 9.3 5.8 1.4e+02 2.9 5.8 2.6 1 1 0 1 1 1 0 Rx N-terminal domain GTP-bdg_M PF16360.5 EAX69434.1 - 1.6 9.4 4.7 11 6.7 0.7 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region CC2-LZ PF16516.5 EAX69434.1 - 2 8.8 11.4 3.9 7.9 8.9 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YtxH PF12732.7 EAX69434.1 - 2.5 8.7 7.4 38 4.9 7.4 2.6 1 1 0 1 1 1 0 YtxH-like protein LMBR1 PF04791.16 EAX69434.1 - 2.6 6.8 4.6 3.3 6.5 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4337 PF14235.6 EAX69434.1 - 4.4 7.4 5.9 7.8 6.6 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31_Bap29_C PF18035.1 EAX69434.1 - 4.9 7.2 10.9 6.7 6.8 9.9 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2408 PF10303.9 EAX69434.1 - 5.1 7.7 11.7 11 6.6 11.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CCDC-167 PF15188.6 EAX69434.1 - 5.2 7.5 10.3 1.9 8.9 7.5 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Cnd1 PF12717.7 EAX69434.1 - 6.7 6.7 13.0 0.36 10.8 1.0 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 NYD-SP28 PF14772.6 EAX69434.1 - 8.6 6.5 15.3 0.87 9.7 5.8 2.3 1 1 1 2 2 2 0 Sperm tail Annexin PF00191.20 EAX69435.1 - 0.12 12.4 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Annexin Chal_sti_synt_N PF00195.19 EAX69436.1 - 0.066 12.6 0.2 0.12 11.7 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX69436.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX69437.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69437.1 - 0.079 13.5 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX69438.1 - 1.9e-06 28.4 0.0 4.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX69438.1 - 0.01 15.7 1.6 0.057 13.3 0.7 2.5 2 1 0 2 2 2 0 KilA-N domain DUF3035 PF11233.8 EAX69439.1 - 0.076 13.3 3.0 0.1 12.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Pox_A32 PF04665.12 EAX69441.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69441.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69441.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69441.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Ly49 PF08391.10 EAX69442.1 - 0.25 11.7 3.2 0.3 11.5 3.2 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX69442.1 - 0.4 10.6 3.0 0.58 10.1 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69443.1 - 7.7e-63 210.7 7.8 8.6e-63 210.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX69444.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69444.1 - 2.8e-05 24.4 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69444.1 - 5e-05 23.1 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69444.1 - 0.00015 21.8 3.1 0.00032 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69444.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69444.1 - 0.0012 18.7 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69444.1 - 0.0018 17.9 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69444.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX69444.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX69444.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69444.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69444.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69444.1 - 0.3 11.4 3.7 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69445.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69445.1 - 0.055 14.0 0.5 0.063 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRE_C2HC PF07530.11 EAX69445.1 - 0.062 13.4 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers LD_cluster2 PF18163.1 EAX69445.1 - 0.084 12.4 0.2 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 SLOG cluster2 PRD PF00874.20 EAX69445.1 - 0.086 13.2 1.1 0.16 12.3 0.2 1.9 2 0 0 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX69446.1 - 0.00012 21.7 0.4 0.00013 21.6 0.4 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX69446.1 - 0.071 11.9 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase PapD_N PF00345.20 EAX69448.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69448.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Ank_2 PF12796.7 EAX69449.1 - 1.1e-106 349.6 52.3 2.3e-16 60.1 1.3 7.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX69449.1 - 1.1e-66 220.3 21.0 2.2e-12 47.2 0.1 9.9 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX69449.1 - 6e-55 181.4 20.8 2.2e-07 31.0 0.3 10.2 11 0 0 11 11 10 9 Ankyrin repeat Ank_3 PF13606.6 EAX69449.1 - 7.8e-54 173.3 11.6 8.2e-06 25.8 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EAX69449.1 - 2.4e-44 148.8 9.6 3e-10 40.1 0.1 6.2 3 1 2 6 6 6 6 Ankyrin repeats (many copies) S4 PF01479.25 EAX69449.1 - 1.8e-05 24.4 0.1 68 3.3 0.0 7.2 9 0 0 9 9 9 0 S4 domain DUF3677 PF12432.8 EAX69449.1 - 2.3e-05 24.6 0.0 78 3.7 0.0 7.1 2 1 7 9 9 9 0 Protein of unknown function (DUF3677) PrmC_N PF17827.1 EAX69449.1 - 9.6e-05 22.9 6.6 82 3.9 0.0 7.2 4 2 4 8 8 8 0 PrmC N-terminal domain RGP PF03214.13 EAX69449.1 - 0.00021 20.6 0.0 32 3.5 0.0 5.5 1 1 8 9 9 9 0 Reversibly glycosylated polypeptide Glyco_hydro_20b PF02838.15 EAX69449.1 - 0.00036 21.3 9.4 10 6.9 0.2 5.7 1 1 6 7 7 7 0 Glycosyl hydrolase family 20, domain 2 Arg_repressor PF01316.21 EAX69449.1 - 0.001 18.7 2.3 84 3.0 0.0 6.7 9 0 0 9 9 9 0 Arginine repressor, DNA binding domain DUF3718 PF12514.8 EAX69449.1 - 0.013 15.7 15.0 2.5 8.3 0.1 7.4 4 2 5 9 9 9 0 Protein of unknown function (DUF3718) Stap_Strp_toxin PF01123.20 EAX69449.1 - 0.016 16.0 11.0 35 5.3 0.1 6.2 1 1 6 7 7 7 0 Staphylococcal/Streptococcal toxin, OB-fold domain ACD PF16671.5 EAX69449.1 - 0.023 13.0 2.5 2.6 6.3 0.0 3.9 1 1 5 7 7 7 0 Actin cross-linking domain Herpes_UL36 PF03586.13 EAX69449.1 - 0.063 12.6 1.7 13 5.0 0.0 3.9 1 1 2 5 5 5 0 Herpesvirus UL36 tegument protein DUF348 PF03990.14 EAX69449.1 - 0.18 11.6 11.5 2.2e+02 1.7 0.0 8.0 10 0 0 10 10 10 0 G5-linked-Ubiquitin-like domain DUF1103 PF06513.11 EAX69449.1 - 0.9 9.1 12.4 0.11 12.1 4.9 2.2 1 1 1 2 2 2 0 Repeat of unknown function (DUF1103) VPS11_C PF12451.8 EAX69449.1 - 9.2 6.6 11.0 1.6e+02 2.6 0.1 4.7 5 0 0 5 5 4 0 Vacuolar protein sorting protein 11 C terminal PG_binding_2 PF08823.11 EAX69450.1 - 0.042 14.2 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF87 PF01935.17 EAX69450.1 - 0.057 13.5 0.7 0.18 11.9 0.7 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain Alba PF01918.21 EAX69450.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Alba PSP PF04046.16 EAX69453.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69454.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX69455.1 - 4.7e-125 415.9 7.0 5.4e-125 415.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX69455.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX69455.1 - 0.088 13.3 1.7 1.2 9.6 1.0 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX69455.1 - 0.11 13.1 0.7 0.49 11.1 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX69455.1 - 0.18 12.1 4.8 1.6 9.1 0.1 3.1 2 1 0 2 2 2 0 Rx N-terminal domain DUF257 PF03192.13 EAX69456.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX69456.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX69457.1 - 5.9e-05 22.6 3.7 0.00011 21.8 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69457.1 - 0.0057 16.7 0.9 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69457.1 - 0.0094 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX69457.1 - 0.051 12.8 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Amidase02_C PF12123.8 EAX69458.1 - 0.0022 17.6 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX69459.1 - 2.2e-26 92.8 10.7 2.6e-26 92.5 10.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69459.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX69461.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein JMY PF15871.5 EAX69463.1 - 0.0099 15.2 0.6 0.014 14.7 0.6 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein Gly-zipper_Omp PF13488.6 EAX69464.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper ActA PF05058.12 EAX69464.1 - 0.14 10.5 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX69464.1 - 0.52 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) KilA-N PF04383.13 EAX69465.1 - 2.4e-41 140.1 0.6 6.5e-41 138.7 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX69466.1 - 1.5e-05 24.6 2.9 2e-05 24.2 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69466.1 - 0.0041 16.8 0.2 0.0054 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX69466.1 - 0.007 15.3 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX69466.1 - 0.029 13.9 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69466.1 - 0.04 13.6 0.2 0.25 11.1 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69466.1 - 0.046 13.5 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX69466.1 - 0.097 12.6 1.2 1 9.3 0.0 3.1 3 1 0 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX69466.1 - 0.13 12.7 2.3 0.17 12.3 1.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PTR PF12789.7 EAX69467.1 - 1.6e-31 108.2 10.9 1.6e-31 108.2 10.9 1.9 2 0 0 2 2 2 1 Phage tail repeat like Phage_fiber PF03335.13 EAX69467.1 - 3.3 8.1 11.2 5 7.6 0.2 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat Ank_2 PF12796.7 EAX69468.1 - 1.4e-35 121.7 8.5 5e-15 55.9 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX69468.1 - 4.2e-25 85.1 0.3 1.2e-05 25.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX69468.1 - 4.9e-25 87.6 1.9 7.8e-07 29.5 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX69468.1 - 2.3e-20 72.1 0.6 0.00019 21.7 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX69468.1 - 5.6e-18 64.8 0.3 2.2e-07 31.0 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX69468.1 - 0.00098 19.3 0.0 14 6.0 0.0 3.3 1 1 2 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Arg_repressor PF01316.21 EAX69468.1 - 0.0018 18.0 0.2 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain Stap_Strp_toxin PF01123.20 EAX69468.1 - 0.0086 16.9 1.4 3.6 8.5 0.1 2.9 1 1 2 3 3 3 1 Staphylococcal/Streptococcal toxin, OB-fold domain DUF249 PF03158.13 EAX69468.1 - 0.01 15.6 0.0 31 4.2 0.0 3.1 3 0 0 3 3 3 0 Multigene family 530 protein DUF3677 PF12432.8 EAX69468.1 - 0.016 15.5 0.0 18 5.7 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3677) LRR_5 PF13306.6 EAX69468.1 - 0.017 15.1 2.0 0.83 9.6 1.9 2.6 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF348 PF03990.14 EAX69468.1 - 0.021 14.6 0.5 64 3.4 0.0 3.8 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain DUF4231 PF14015.6 EAX69468.1 - 0.021 15.3 0.0 19 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) S4 PF01479.25 EAX69468.1 - 0.022 14.5 0.0 18 5.1 0.0 3.0 3 0 0 3 3 3 0 S4 domain DUF1861 PF08950.10 EAX69468.1 - 0.032 13.5 0.0 5.3 6.2 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1861) DUF685 PF05085.12 EAX69468.1 - 0.098 12.0 4.3 3.2 7.0 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF685) DUF4268 PF14088.6 EAX69468.1 - 0.67 9.8 5.2 11 5.9 0.3 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4268) Amidase02_C PF12123.8 EAX69469.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX69470.1 - 2.7e-31 108.9 2.5 3e-31 108.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX69471.1 - 0.0088 16.5 0.7 0.017 15.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX69474.1 - 0.0012 18.5 0.1 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX69475.1 - 3.3e-21 76.0 3.7 3.3e-21 76.0 3.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX69475.1 - 0.28 10.8 1.2 0.44 10.1 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) T5orf172 PF10544.9 EAX69477.1 - 5e-07 30.2 0.4 1e-06 29.2 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF5623 PF18536.1 EAX69478.1 - 0.083 13.2 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX69478.1 - 0.86 9.6 9.9 0.29 11.1 4.4 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX69480.1 - 4.6e-07 29.6 0.2 5.4e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX69482.1 - 1.7e-64 216.1 6.7 1.8e-64 215.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX69482.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX69483.1 - 5.8e-28 97.0 0.7 1.3e-27 95.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69483.1 - 0.0027 18.3 0.1 0.0067 17.0 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Trypan_PARP PF05887.11 EAX69484.1 - 0.022 14.8 10.4 0.03 14.3 10.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX69486.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX69487.1 - 5.3e-41 139.0 1.9 6.4e-41 138.7 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX69487.1 - 0.39 10.7 2.8 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein PapD_N PF00345.20 EAX69489.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1731 PF08338.11 EAX69490.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Noggin PF05806.12 EAX69491.1 - 0.028 14.3 0.8 0.036 14.0 0.8 1.0 1 0 0 1 1 1 0 Noggin Pox_A32 PF04665.12 EAX69492.1 - 1.4e-07 31.2 0.3 1.7e-07 30.9 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX69492.1 - 0.0047 15.8 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX69492.1 - 0.018 14.6 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX69492.1 - 0.045 13.7 0.4 0.43 10.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX69492.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX69493.1 - 3.1e-25 89.0 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX69493.1 - 0.15 12.5 0.8 0.48 10.9 0.2 1.9 1 1 1 2 2 2 0 Cell division protein ZapB Mito_fiss_reg PF05308.11 EAX69494.1 - 0.12 12.4 0.5 0.13 12.4 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69494.1 - 1 8.8 3.0 1 8.7 3.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX69495.1 - 1.5e-76 257.0 7.0 6.7e-76 254.9 7.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX69496.1 - 1.2e-16 60.5 1.9 1.2e-16 60.5 1.9 4.7 3 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX69496.1 - 0.01 15.5 1.1 0.01 15.5 1.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX69496.1 - 0.049 13.4 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX69497.1 - 4.1e-07 29.7 1.2 6.8e-07 29.0 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX69497.1 - 0.054 13.8 0.2 0.099 13.0 0.1 1.6 1 1 0 1 1 1 0 PRD domain Armet PF10208.9 EAX69498.1 - 0.061 13.3 0.0 0.062 13.2 0.0 1.0 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding DUF4107 PF13389.6 EAX69499.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX69500.1 - 0.022 15.2 1.4 0.028 14.9 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX69501.1 - 9.2e-58 194.2 4.2 1e-57 194.1 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX69503.1 - 2.6e-23 82.7 4.0 3.6e-23 82.2 4.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5623 PF18536.1 EAX69504.1 - 0.047 14.0 0.1 0.059 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) JMY PF15871.5 EAX69505.1 - 0.049 12.9 0.3 0.07 12.4 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein tRNA_synt_1c_R1 PF04558.15 EAX69506.1 - 0.0056 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69506.1 - 0.0086 15.7 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX69506.1 - 0.054 12.7 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Tho2 PF11262.8 EAX69508.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TPR_MLP1_2 PF07926.12 EAX69509.1 - 0.058 13.5 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX69509.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX69509.1 - 6.2 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX69510.1 - 2.9e-21 75.9 5.1 4e-21 75.4 5.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX69511.1 - 4.8e-23 81.7 4.2 6.1e-23 81.4 4.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX69512.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX69512.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX69512.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX69512.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX69513.1 - 8.1e-07 28.7 2.5 8.1e-07 28.7 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX69513.1 - 3.3e-05 23.7 0.3 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69513.1 - 4.5e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69513.1 - 0.00056 20.0 5.0 0.001 19.1 4.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69513.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69513.1 - 0.0023 17.7 1.1 0.0041 17.0 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69513.1 - 0.0065 16.1 2.9 0.016 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69513.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX69513.1 - 0.086 12.9 0.7 1.3 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX69513.1 - 0.091 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69513.1 - 0.11 13.0 0.1 0.94 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69513.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69513.1 - 0.6 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX69513.1 - 0.71 10.6 11.7 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DNA_pol_B_2 PF03175.13 EAX69514.1 - 1.1e-20 74.0 8.2 5.3e-20 71.7 8.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral YmaF PF12788.7 EAX69515.1 - 0.15 12.6 1.5 6.4 7.4 0.1 2.0 1 1 0 1 1 1 0 YmaF family DUF4106 PF13388.6 EAX69516.1 - 2.6e-184 613.3 25.8 9.2e-184 611.5 25.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3213 PF11491.8 EAX69519.1 - 0.034 14.3 0.4 0.083 13.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KIP1 PF07765.12 EAX69519.1 - 3.2 7.9 7.3 14 5.9 0.4 2.4 1 1 1 2 2 2 0 KIP1-like protein DUF4108 PF13390.6 EAX69521.1 - 4.9e-59 198.3 5.2 5.5e-59 198.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX69521.1 - 0.1 12.8 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide YmaF PF12788.7 EAX69523.1 - 0.13 12.8 1.0 2.3 8.8 1.0 2.0 1 1 1 2 2 2 0 YmaF family Pox_A32 PF04665.12 EAX69524.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Apolipoprotein PF01442.18 EAX69525.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3839 PF12943.7 EAX69526.1 - 3e-80 269.2 11.4 3.9e-80 268.8 11.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX69526.1 - 0.073 12.6 0.5 0.39 10.2 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 Amidase02_C PF12123.8 EAX69527.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF5623 PF18536.1 EAX69529.1 - 0.082 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX69529.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX69530.1 - 9.4e-17 61.0 2.9 1.1e-16 60.8 2.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Peptidase_S64 PF08192.11 EAX69531.1 - 0.013 14.0 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 UCH PF00443.29 EAX69531.1 - 0.018 14.5 0.9 0.45 10.0 0.9 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Fungal_lectin_2 PF18647.1 EAX69531.1 - 0.033 14.6 0.9 0.06 13.8 0.2 1.7 1 1 1 2 2 2 0 Alpha-galactosyl-binding fungal lectin Pox_A32 PF04665.12 EAX69532.1 - 1.2e-06 28.2 1.6 1.2e-06 28.2 1.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX69532.1 - 3.2e-05 23.7 0.3 0.31 10.7 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69532.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69532.1 - 0.00033 20.7 4.3 0.00055 20.0 3.5 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69532.1 - 0.00064 19.5 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69532.1 - 0.0033 17.3 1.6 0.0091 15.8 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69532.1 - 0.004 16.8 2.2 0.015 14.9 0.1 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69532.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX69532.1 - 0.078 12.5 0.0 0.26 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX69532.1 - 0.08 13.0 0.7 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX69532.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX69532.1 - 0.12 12.8 0.1 0.89 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX69532.1 - 0.59 10.8 11.3 0.32 11.7 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF5365 PF17326.2 EAX69533.1 - 0.01 16.2 0.2 0.013 15.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4107 PF13389.6 EAX69534.1 - 2.1e-72 242.6 3.8 2.8e-72 242.2 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX69536.1 - 0.019 15.5 0.8 0.038 14.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX69537.1 - 5.4e-156 517.2 13.4 6.2e-156 517.0 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX69537.1 - 0.082 13.2 0.2 2 8.8 0.0 2.8 3 1 0 3 3 3 0 Rx N-terminal domain LD_cluster2 PF18163.1 EAX69537.1 - 0.12 11.9 0.1 0.68 9.4 0.0 1.9 1 1 1 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX69537.1 - 0.18 11.7 1.5 0.7 9.7 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX69537.1 - 0.81 10.2 5.6 6.9 7.2 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX69538.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX69540.1 - 0.011 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX69542.1 - 9e-05 22.0 3.6 0.00017 21.2 3.6 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69542.1 - 0.0044 17.0 0.7 0.011 15.8 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69542.1 - 0.0084 15.7 0.2 0.017 14.7 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX69542.1 - 0.047 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX69542.1 - 0.1 12.9 1.9 0.18 12.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DNA_pol_B_2 PF03175.13 EAX69544.1 - 1.4e-10 40.6 2.0 4.9e-10 38.9 2.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69544.1 - 0.11 12.5 0.0 0.88 9.6 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX69544.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX69545.1 - 3.7e-06 26.9 4.1 3.7e-06 26.9 4.1 4.7 3 3 2 5 5 5 2 Phage tail repeat like DUF4738 PF15889.5 EAX69545.1 - 0.013 15.4 2.0 0.013 15.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) DUF4116 PF13475.6 EAX69545.1 - 0.045 13.5 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX69545.1 - 0.13 12.8 0.2 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX69545.1 - 1 8.9 15.5 0.11 12.1 3.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) IKKbetaNEMObind PF12179.8 EAX69547.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain TMP PF05017.14 EAX69548.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX69549.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX69549.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX69551.1 - 3.7e-35 120.2 0.1 7.7e-35 119.1 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX69551.1 - 0.0077 16.8 0.2 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family Ank_2 PF12796.7 EAX69553.1 - 4.6e-67 222.6 33.9 3e-15 56.6 0.7 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX69553.1 - 4.4e-61 200.8 14.7 1.7e-09 37.7 0.0 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX69553.1 - 3.7e-55 183.6 19.2 1e-11 45.1 0.1 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX69553.1 - 7.9e-53 175.8 27.0 1.1e-12 47.9 0.3 6.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69553.1 - 6.5e-49 158.2 10.1 1.1e-06 28.5 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat ThiS-like PF14453.6 EAX69553.1 - 2.2e-06 27.6 13.2 9.1 6.4 0.1 7.0 1 1 6 7 7 7 1 ThiS-like ubiquitin MetallophosN PF16371.5 EAX69553.1 - 0.00053 20.2 0.0 0.59 10.4 0.0 3.8 2 2 1 3 3 3 1 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX69553.1 - 0.0012 19.0 2.8 1.4e+02 2.8 0.0 5.8 1 1 6 7 7 7 0 Pleckstrin homology domain CEP44 PF15007.6 EAX69553.1 - 0.0074 16.5 0.0 68 3.6 0.0 4.9 2 2 3 6 6 6 0 Centrosomal spindle body, CEP44 Phage_G PF02306.15 EAX69553.1 - 0.025 14.3 5.4 27 4.5 0.1 4.4 1 1 4 5 5 5 0 Major spike protein (G protein) DUF762 PF05555.11 EAX69553.1 - 2.7 7.5 6.7 7.7 6.0 0.1 3.8 2 1 2 4 4 4 0 Coxiella burnetii protein of unknown function (DUF762) TMP PF05017.14 EAX69554.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69555.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX69557.1 - 2.7e-117 390.5 7.9 3.1e-117 390.3 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX69557.1 - 0.068 12.7 1.1 0.093 12.2 0.6 1.5 1 1 0 1 1 1 0 Z1 domain PSP PF04046.16 EAX69559.1 - 0.2 11.5 3.0 0.21 11.5 0.3 2.2 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX69560.1 - 0.024 15.1 2.9 11 7.2 0.2 3.0 3 0 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX69563.1 - 2.5e-113 370.9 12.3 2.6e-16 60.0 0.0 6.7 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX69563.1 - 1.5e-79 261.4 10.7 1.2e-09 38.5 0.0 9.2 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX69563.1 - 1.1e-72 237.5 5.4 2.1e-05 24.7 0.0 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX69563.1 - 7.7e-69 226.9 12.5 5.3e-08 33.0 0.0 11.3 1 1 11 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69563.1 - 5.2e-53 170.8 0.8 0.01 16.3 0.0 11.7 12 0 0 12 12 12 10 Ankyrin repeat DUF1147 PF06615.11 EAX69563.1 - 6.9e-10 38.8 24.5 19 5.4 0.1 10.7 11 0 0 11 11 11 8 Protein of unknown function (DUF1147) DUF1897 PF09005.10 EAX69563.1 - 2.2e-07 30.2 4.2 1.3e+02 2.1 0.0 11.8 13 0 0 13 13 13 0 Domain of unknown function (DUF1897) KH_4 PF13083.6 EAX69563.1 - 8.5e-05 22.4 4.8 1.4e+02 2.5 0.0 8.9 11 0 0 11 11 11 0 KH domain DUF3839 PF12943.7 EAX69567.1 - 4e-121 403.0 11.6 5e-121 402.7 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX69567.1 - 0.047 13.9 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 KELK PF15796.5 EAX69567.1 - 0.23 12.0 3.1 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX69567.1 - 0.47 10.8 4.2 1.2 9.5 0.1 3.2 4 0 0 4 4 4 0 PRD domain DUF3839 PF12943.7 EAX69569.1 - 7.1e-137 454.6 10.8 8.8e-137 454.3 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX69569.1 - 0.086 13.3 0.5 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX69569.1 - 0.11 12.9 3.0 0.12 12.8 0.6 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX69569.1 - 0.3 11.6 8.6 0.82 10.2 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GDE_C PF06202.14 EAX69571.1 - 0.0051 15.8 0.7 1.5 7.7 0.1 2.1 1 1 1 2 2 2 2 Amylo-alpha-1,6-glucosidase Neuromodulin PF06614.11 EAX69571.1 - 1.8 8.7 7.3 54 3.9 0.7 3.2 1 1 3 4 4 4 0 Neuromodulin YfhE PF14152.6 EAX69571.1 - 2.9 8.0 21.6 3.1e+02 1.6 0.0 8.9 10 0 0 10 10 10 0 YfhE-like protein Forkhead_N PF08430.12 EAX69571.1 - 8.6 7.0 24.8 1.8e+04 -5.1 24.8 2.8 1 1 0 1 1 1 0 Forkhead N-terminal region Peptidase_S64 PF08192.11 EAX69572.1 - 0.0062 15.1 0.0 0.0063 15.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 DUF4106 PF13388.6 EAX69575.1 - 2.1e-94 317.2 5.2 2.1e-94 317.2 5.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) PTR PF12789.7 EAX69576.1 - 2e-16 59.8 2.5 2e-16 59.8 2.5 4.2 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX69576.1 - 0.029 14.0 8.0 0.043 13.4 5.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX69577.1 - 4.3e-63 211.5 6.4 4.8e-63 211.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1731 PF08338.11 EAX69579.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX69581.1 - 5e-34 116.5 0.3 1.2e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69581.1 - 0.0059 17.2 0.0 0.015 15.9 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX69582.1 - 5.6e-10 38.7 1.4 1.1e-09 37.7 0.9 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2897 PF11446.8 EAX69583.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX69584.1 - 6.2e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69584.1 - 7.6e-05 22.8 3.1 0.00015 21.8 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69584.1 - 0.00039 20.2 0.0 0.00061 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69584.1 - 0.00088 19.1 0.9 0.0029 17.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69584.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69584.1 - 0.0079 15.9 0.4 0.19 11.5 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX69584.1 - 0.044 13.2 0.1 0.068 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX69584.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX69584.1 - 0.11 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX69584.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69584.1 - 0.21 11.8 4.5 5.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) YmaF PF12788.7 EAX69585.1 - 0.13 12.8 1.7 2 9.0 1.7 2.0 1 1 1 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX69585.1 - 0.57 10.5 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX69586.1 - 1.4e-25 90.2 4.4 2.1e-25 89.6 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX69587.1 - 2.2e-08 33.9 0.6 2.5e-08 33.7 0.6 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69587.1 - 0.0046 16.6 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX69587.1 - 0.072 13.0 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX69587.1 - 0.082 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2939 PF11159.8 EAX69589.1 - 0.034 14.5 0.3 0.046 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX69589.1 - 1.6 9.4 4.8 2.8 8.6 4.8 1.5 1 1 0 1 1 1 0 Homeodomain-like domain Ank_2 PF12796.7 EAX69590.1 - 1.1e-97 320.7 53.6 5.5e-18 65.3 3.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAX69590.1 - 9.9e-82 266.1 23.3 2.7e-09 37.0 0.2 9.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 EAX69590.1 - 1.7e-80 264.4 29.5 3.5e-11 43.4 0.1 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX69590.1 - 8.3e-72 236.3 38.5 1.2e-11 44.5 0.2 7.4 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69590.1 - 9.6e-64 203.8 17.1 7.9e-07 28.9 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat ThiS-like PF14453.6 EAX69590.1 - 8.5e-10 38.5 18.8 5.1 7.2 0.1 9.0 1 1 8 9 9 9 4 ThiS-like ubiquitin CEP44 PF15007.6 EAX69590.1 - 2e-06 28.0 0.0 27 4.9 0.0 6.9 3 1 5 8 8 8 0 Centrosomal spindle body, CEP44 MetallophosN PF16371.5 EAX69590.1 - 3.4e-06 27.2 0.0 0.24 11.7 0.0 5.2 3 2 2 5 5 5 1 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX69590.1 - 1.6e-05 25.1 2.9 1.5e+02 2.8 0.0 7.4 1 1 8 9 9 9 0 Pleckstrin homology domain Phage_G PF02306.15 EAX69590.1 - 0.019 14.7 7.3 12 5.6 0.2 4.9 1 1 2 4 4 4 0 Major spike protein (G protein) Staphylokinase PF02821.16 EAX69590.1 - 2.1 8.8 6.0 2.3e+02 2.2 0.0 5.2 1 1 5 7 7 7 0 Staphylokinase/Streptokinase family PapD_N PF00345.20 EAX69591.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Nmad5 PF18757.1 EAX69592.1 - 0.00058 20.1 14.3 0.23 11.6 1.9 4.1 1 1 3 4 4 4 4 Nucleotide modification associated domain 5 DUF5383 PF17355.2 EAX69592.1 - 1.6 9.1 38.5 1.4 9.3 4.9 4.4 1 1 2 4 4 4 0 Family of unknown function (DUF5383) DUF2897 PF11446.8 EAX69593.1 - 0.19 11.6 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69594.1 - 3.6e-61 205.3 7.1 4.1e-61 205.1 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) IL1 PF00340.19 EAX69595.1 - 0.048 13.3 1.3 0.091 12.4 0.2 1.9 2 0 0 2 2 2 0 Interleukin-1 / 18 VirB3 PF05101.13 EAX69596.1 - 5.7 7.2 11.4 24 5.3 4.3 3.3 1 1 2 3 3 3 0 Type IV secretory pathway, VirB3-like protein Amidase02_C PF12123.8 EAX69598.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX69599.1 - 3.4e-06 27.5 0.2 8.5e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX69599.1 - 0.011 15.6 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX69599.1 - 0.014 15.0 0.9 0.13 11.7 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain PapD_N PF00345.20 EAX69601.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69601.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family FliJ PF02050.16 EAX69602.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1493 PF07377.12 EAX69603.1 - 0.028 14.9 0.7 0.057 13.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX69606.1 - 2.7e-41 139.9 0.6 7.3e-41 138.5 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX69607.1 - 5.4e-06 26.9 0.2 1.1e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX69607.1 - 0.015 15.1 0.3 0.081 12.8 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain FAS_N PF17828.1 EAX69609.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69610.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69610.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AbiJ_NTD4 PF18863.1 EAX69611.1 - 0.015 15.8 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 PapD_N PF00345.20 EAX69613.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX69614.1 - 2.9e-127 423.1 6.7 3.4e-127 422.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1840 PF08895.11 EAX69615.1 - 0.01 16.2 4.9 0.01 16.2 4.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1840) DUF4746 PF15928.5 EAX69615.1 - 0.033 13.6 13.0 0.038 13.4 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mlh1_C PF16413.5 EAX69615.1 - 0.11 11.8 4.5 0.15 11.4 4.5 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus WSD PF15613.6 EAX69615.1 - 0.13 12.7 3.9 0.12 12.9 1.3 2.0 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif AATF-Che1 PF13339.6 EAX69615.1 - 0.52 11.0 7.8 1 10.1 7.8 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor NOA36 PF06524.12 EAX69615.1 - 0.61 9.4 6.2 0.73 9.1 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cytomega_UL84 PF06284.11 EAX69615.1 - 1.9 6.9 6.0 2.4 6.5 6.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein HNH_3 PF13392.6 EAX69617.1 - 1.5e-07 31.0 0.3 2.7e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Kazal_1 PF00050.21 EAX69618.1 - 0.0022 18.0 0.5 0.004 17.1 0.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Malt_amylase_C PF16657.5 EAX69618.1 - 0.0051 16.9 0.0 0.0063 16.6 0.0 1.1 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF4107 PF13389.6 EAX69620.1 - 8.6e-74 247.1 4.8 1.1e-73 246.7 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX69620.1 - 0.13 10.7 1.0 0.18 10.2 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase KilA-N PF04383.13 EAX69621.1 - 5.3e-35 119.6 1.8 1.1e-34 118.7 0.1 2.2 2 1 0 2 2 2 1 KilA-N domain Stanniocalcin PF03298.13 EAX69621.1 - 0.18 11.1 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 Stanniocalcin family DNA_pol_B_2 PF03175.13 EAX69622.1 - 6.2e-09 35.2 1.0 1.2e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX69622.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX69622.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX69624.1 - 3e-18 65.7 0.9 6.3e-18 64.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69624.1 - 0.0076 16.9 0.0 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family FPN1 PF06963.12 EAX69624.1 - 0.36 9.4 0.1 0.45 9.0 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) HCBP_related PF06594.11 EAX69625.1 - 0.11 12.4 0.0 1.4e+02 2.5 0.0 3.7 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain Chordopox_A30L PF06015.12 EAX69625.1 - 0.67 9.8 5.4 11 5.9 0.3 2.4 1 1 2 3 3 3 0 Chordopoxvirus A30L protein FAS_N PF17828.1 EAX69626.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69627.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69627.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX69628.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69629.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX69630.1 - 9.4e-05 22.0 3.8 0.00017 21.1 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69630.1 - 0.0056 16.7 1.0 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69630.1 - 0.0089 15.6 0.2 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Csm1_N PF18504.1 EAX69631.1 - 0.00019 21.7 4.4 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX69631.1 - 0.00068 19.7 9.1 0.0033 17.5 9.2 1.9 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 EAX69631.1 - 0.0027 18.1 3.7 0.0044 17.4 3.7 1.4 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX69631.1 - 0.0041 16.1 4.7 0.0047 15.9 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX69631.1 - 0.0054 16.5 5.5 0.0072 16.2 1.4 2.9 1 1 2 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX69631.1 - 0.0063 16.8 4.0 0.0095 16.3 4.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 EAX69631.1 - 0.013 15.7 6.2 0.016 15.4 6.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EAX69631.1 - 0.013 15.4 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HemX PF04375.14 EAX69631.1 - 0.018 14.4 4.0 0.022 14.0 4.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 EAX69631.1 - 0.025 13.7 3.8 0.025 13.7 3.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EAX69631.1 - 0.027 14.5 7.4 0.043 13.9 7.2 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 EAX69631.1 - 0.028 13.8 4.9 0.033 13.5 4.9 1.1 1 0 0 1 1 1 0 FAM76 protein GNT-I PF03071.15 EAX69631.1 - 0.043 12.6 0.9 0.058 12.2 0.9 1.1 1 0 0 1 1 1 0 GNT-I family ATG16 PF08614.11 EAX69631.1 - 0.083 13.1 10.7 0.11 12.7 10.7 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EAX69631.1 - 0.092 12.5 7.4 1.2 8.9 4.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 EAX69631.1 - 0.11 11.8 3.2 0.13 11.5 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 EAX69631.1 - 0.49 10.5 6.6 31 4.8 0.0 2.5 1 1 0 2 2 2 0 bZIP transcription factor COMP PF11598.8 EAX69631.1 - 0.98 9.9 5.8 2.3 8.7 3.1 2.2 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 EAX69631.1 - 2.2 8.1 8.5 2 8.2 3.6 2.2 1 1 1 2 2 2 0 Septum formation initiator PapD_N PF00345.20 EAX69632.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69632.1 - 0.071 13.1 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX69633.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69633.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69633.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69633.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX69634.1 - 7.5e-06 25.9 7.2 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX69634.1 - 1.3 9.7 4.2 8.4 7.0 1.8 2.7 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX69634.1 - 3.1 8.2 9.4 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat PapD_N PF00345.20 EAX69635.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69635.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF1493 PF07377.12 EAX69638.1 - 0.024 15.1 1.6 0.03 14.8 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX69639.1 - 0.12 12.1 0.6 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) KilA-N PF04383.13 EAX69641.1 - 1.9e-34 117.8 1.1 2.4e-34 117.5 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX69642.1 - 3.3e-07 30.8 0.2 6.7e-07 29.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF2939 PF11159.8 EAX69643.1 - 0.02 15.3 0.7 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69643.1 - 1.6 7.7 4.0 1.7 7.6 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX69643.1 - 3.8 8.2 6.6 8.4 7.1 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX69643.1 - 4.1 7.4 7.6 4.4 7.3 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69644.1 - 0.004 17.1 0.2 0.0054 16.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX69645.1 - 1.5e-06 27.9 4.6 1.5e-06 27.9 4.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX69645.1 - 4e-05 23.4 0.3 0.42 10.3 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69645.1 - 5.3e-05 23.5 0.2 0.00037 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69645.1 - 0.00049 20.1 4.8 0.001 19.1 4.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69645.1 - 0.00088 19.1 0.1 0.0017 18.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX69645.1 - 0.006 16.2 2.9 0.015 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX69645.1 - 0.0064 16.3 2.0 0.017 14.9 1.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69645.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX69645.1 - 0.083 12.9 0.6 1.2 9.2 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX69645.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX69645.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX69645.1 - 0.11 12.9 0.1 1 9.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX69645.1 - 0.98 10.1 12.5 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX69645.1 - 1 9.7 5.5 10 6.4 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69647.1 - 1.5e-24 86.8 3.7 2.1e-24 86.3 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RecO_C PF02565.15 EAX69647.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal Trypan_PARP PF05887.11 EAX69648.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX69649.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Ank_4 PF13637.6 EAX69650.1 - 8.7e-21 74.0 7.0 2.4e-08 34.4 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX69650.1 - 3.9e-14 53.0 0.6 1.4e-05 25.5 0.3 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX69650.1 - 5.1e-11 42.6 0.2 1e-06 28.8 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69650.1 - 2.1e-10 39.9 2.2 0.038 14.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX69650.1 - 1.5e-08 34.7 4.7 0.0042 17.5 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat CIDR1_gamma PF18562.1 EAX69651.1 - 0.0025 17.9 3.3 0.0025 17.9 1.1 2.1 2 0 0 2 2 2 1 Cysteine-Rich Interdomain Region 1 gamma WRKY PF03106.15 EAX69651.1 - 0.015 15.5 2.4 0.032 14.4 0.3 2.4 2 0 0 2 2 2 0 WRKY DNA -binding domain FLYWCH PF04500.16 EAX69651.1 - 0.045 13.9 0.6 0.094 12.8 0.6 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF4108 PF13390.6 EAX69652.1 - 5.9e-41 139.7 2.2 6.4e-41 139.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX69652.1 - 0.12 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein RGS12_us1 PF16613.5 EAX69653.1 - 0.32 11.3 3.4 0.52 10.6 3.4 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 DUF3839 PF12943.7 EAX69654.1 - 4.4e-80 268.6 11.6 5.8e-80 268.2 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69654.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX69654.1 - 0.069 12.7 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Trypan_PARP PF05887.11 EAX69655.1 - 0.032 14.2 8.7 0.05 13.6 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69655.1 - 6.6 7.2 6.1 9.5 6.7 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX69656.1 - 0.039 14.4 1.5 0.053 14.0 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69656.1 - 0.044 12.8 0.1 0.045 12.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX69657.1 - 3.1e-120 400.1 11.6 3.9e-120 399.8 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69657.1 - 0.15 12.6 2.6 5.3 7.6 0.0 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RFX_DNA_binding PF02257.15 EAX69660.1 - 0.00036 21.1 0.3 0.00052 20.6 0.3 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX69660.1 - 0.0035 17.8 2.4 0.0053 17.2 2.4 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX69660.1 - 0.12 12.4 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain IstB_IS21 PF01695.17 EAX69661.1 - 2.2e-05 24.3 0.3 0.28 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69661.1 - 2.4e-05 24.6 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69661.1 - 0.00033 20.7 4.6 0.0005 20.1 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69661.1 - 0.00045 20.0 0.1 0.001 18.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69661.1 - 0.0013 18.6 0.8 0.0029 17.4 0.4 1.8 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX69661.1 - 0.0015 18.0 2.2 0.0015 18.0 2.2 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX69661.1 - 0.0045 16.6 2.3 0.021 14.5 0.1 2.6 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69661.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69661.1 - 0.048 14.1 0.1 0.64 10.5 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX69661.1 - 0.054 13.0 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 TPK_catalytic PF04263.16 EAX69661.1 - 0.061 13.4 0.7 0.94 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX69661.1 - 0.063 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX69661.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69661.1 - 0.54 10.5 4.7 8.1 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX69661.1 - 4.8 7.9 11.1 0.27 11.9 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX69662.1 - 4.2e-133 442.2 14.5 1.3e-132 440.7 14.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69662.1 - 0.077 13.4 2.7 0.063 13.7 0.6 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX69662.1 - 0.11 13.0 7.3 0.68 10.4 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX69662.1 - 0.12 12.8 1.2 1.5 9.3 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function PapD_N PF00345.20 EAX69664.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69664.1 - 0.065 13.2 0.5 0.097 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX69665.1 - 0.01 16.2 0.4 0.012 16.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) ATP11 PF06644.11 EAX69665.1 - 3.3 7.4 11.0 3.9 7.2 11.0 1.1 1 0 0 1 1 1 0 ATP11 protein TERB2 PF15101.6 EAX69665.1 - 3.4 7.7 5.5 3.7 7.6 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX69666.1 - 0.054 13.4 0.6 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX69667.1 - 4.8e-07 29.5 2.3 4.8e-07 29.5 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69667.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69667.1 - 5.7e-05 22.9 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69667.1 - 0.00019 21.5 3.7 0.00042 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69667.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69667.1 - 0.0017 18.2 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69667.1 - 0.0019 17.9 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69667.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69667.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69667.1 - 0.09 13.2 0.1 0.76 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69667.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69667.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69668.1 - 4.4e-135 448.7 14.9 5.5e-135 448.4 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX69668.1 - 0.046 14.0 1.5 0.089 13.0 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function DUF29 PRD PF00874.20 EAX69668.1 - 0.49 10.7 4.4 0.9 9.9 0.1 3.1 3 1 0 3 3 3 0 PRD domain KELK PF15796.5 EAX69668.1 - 0.49 10.9 5.2 1.5 9.3 0.1 3.1 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX69669.1 - 4.3e-07 29.6 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) UPF0239 PF06783.11 EAX69670.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF4107 PF13389.6 EAX69671.1 - 6.6e-73 244.2 3.8 8.5e-73 243.8 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DEAD PF00270.29 EAX69673.1 - 1.3e-07 31.6 0.1 5.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX69673.1 - 8.9e-06 25.8 0.5 2.4e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HGD-D PF06050.13 EAX69673.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3213 PF11491.8 EAX69673.1 - 0.086 13.0 0.2 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DUF441 PF04284.13 EAX69673.1 - 0.089 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Helicase_C PF00271.31 EAX69673.1 - 0.57 10.5 3.8 1.5 9.2 1.8 2.6 1 1 1 2 2 2 0 Helicase conserved C-terminal domain DUF3839 PF12943.7 EAX69674.1 - 2.9e-79 266.0 9.9 3.7e-79 265.6 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69674.1 - 0.02 15.3 0.4 0.024 15.1 0.4 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX69674.1 - 0.063 12.8 0.4 0.46 10.0 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX69674.1 - 0.22 11.4 1.5 0.66 9.8 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DNA_pol_B_2 PF03175.13 EAX69675.1 - 8.1e-23 81.0 5.0 1e-22 80.7 5.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX69676.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX69676.1 - 0.038 14.0 0.5 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin AbfS_sensor PF18225.1 EAX69679.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain TMP PF05017.14 EAX69682.1 - 0.059 13.9 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX69683.1 - 5e-117 389.6 8.2 5.7e-117 389.4 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX69683.1 - 0.024 14.9 0.2 0.091 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF3839 PF12943.7 EAX69688.1 - 7.8e-147 487.2 10.7 9.1e-147 487.0 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX69688.1 - 0.45 10.8 3.1 4.8 7.5 0.0 3.0 2 1 1 3 3 3 0 Rx N-terminal domain Trypan_PARP PF05887.11 EAX69689.1 - 0.03 14.3 8.3 0.047 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69689.1 - 3.7 8.0 5.1 5.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2897 PF11446.8 EAX69691.1 - 1.6 8.7 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69692.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX69693.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_4 PF13637.6 EAX69695.1 - 2.3e-19 69.5 0.1 3.2e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX69695.1 - 1.5e-15 56.9 2.7 1.4e-07 31.7 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX69695.1 - 1.3e-14 54.5 1.9 2.4e-14 53.7 1.9 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX69695.1 - 2e-14 52.3 0.3 8.1e-07 28.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX69695.1 - 4.2e-13 49.2 2.1 5.8e-09 36.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX69695.1 - 0.0061 16.7 1.4 0.19 11.9 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3718) CCDC84 PF14968.6 EAX69695.1 - 0.11 12.1 1.2 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 Coiled coil protein 84 Pox_A32 PF04665.12 EAX69696.1 - 7.3e-08 32.2 0.9 8.6e-08 31.9 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69696.1 - 0.0036 17.0 0.1 0.0038 16.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX69696.1 - 0.031 14.3 0.6 0.073 13.1 0.5 1.6 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX69696.1 - 0.067 12.9 0.0 0.097 12.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69696.1 - 0.092 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX69697.1 - 0.01 16.3 0.4 0.014 15.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Ank_4 PF13637.6 EAX69698.1 - 4.3e-10 39.9 0.1 4.8e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX69698.1 - 1.3e-06 28.2 0.2 0.0039 17.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX69698.1 - 5.2e-06 26.7 0.1 0.11 13.0 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX69698.1 - 0.00033 21.2 0.1 0.00036 21.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX69698.1 - 0.00044 20.5 0.3 0.00073 19.8 0.3 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX69698.1 - 0.028 14.2 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein TMP PF05017.14 EAX69699.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69700.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX69701.1 - 1.7e-22 79.9 4.2 2.2e-22 79.6 4.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX69701.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Amidase02_C PF12123.8 EAX69703.1 - 0.004 16.8 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_D5 PF03288.16 EAX69704.1 - 3.3e-06 27.5 0.3 4.9e-06 26.9 0.3 1.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX69704.1 - 0.016 15.8 0.1 0.022 15.4 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX69704.1 - 0.039 13.9 0.2 0.057 13.4 0.2 1.3 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX69705.1 - 4.8e-62 208.1 5.7 5.4e-62 208.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX69706.1 - 0.11 12.4 1.9 0.22 11.4 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) VirE PF05272.11 EAX69707.1 - 1.1e-05 25.3 0.1 1.8e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX69707.1 - 5.8e-05 23.5 2.2 0.00034 21.0 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX69707.1 - 0.05 14.0 0.3 0.17 12.3 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF3198 PF11433.8 EAX69707.1 - 0.13 12.1 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) YmaF PF12788.7 EAX69708.1 - 0.17 12.4 1.6 2.3 8.8 1.7 2.0 1 1 0 1 1 1 0 YmaF family FAS_N PF17828.1 EAX69709.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PRA-PH PF01503.17 EAX69710.1 - 0.39 11.2 3.0 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4108 PF13390.6 EAX69711.1 - 8.7e-53 178.1 4.4 9.6e-53 178.0 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX69713.1 - 4e-62 209.8 2.2 4.8e-62 209.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX69713.1 - 0.025 14.1 0.2 0.028 13.9 0.2 1.0 1 0 0 1 1 1 0 Z1 domain YmgB PF10798.8 EAX69714.1 - 0.0037 17.0 0.1 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR TOM13 PF08219.11 EAX69714.1 - 0.08 12.9 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein TOM13 DNA_pol_B_2 PF03175.13 EAX69715.1 - 2e-08 33.6 1.5 3.6e-08 32.7 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX69715.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 T5orf172 PF10544.9 EAX69716.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX69717.1 - 7.3e-35 119.2 0.1 1.3e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX69717.1 - 0.0092 16.6 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 Parathyroid hormone family EVC2_like PF12297.8 EAX69717.1 - 0.044 12.5 2.5 0.052 12.2 2.5 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF1493 PF07377.12 EAX69719.1 - 0.014 15.8 0.6 0.027 14.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX69720.1 - 3.6e-27 95.4 11.5 3.7e-26 92.0 11.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX69721.1 - 0.019 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69721.1 - 0.072 13.1 0.7 0.1 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) hEGF PF12661.7 EAX69722.1 - 2.9 8.6 5.1 7.9 7.3 5.1 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF T5orf172 PF10544.9 EAX69723.1 - 6.8e-08 33.0 0.4 1.4e-07 32.0 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX69723.1 - 0.13 13.0 0.3 0.35 11.6 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DNA_pol_B_2 PF03175.13 EAX69724.1 - 5.7e-17 61.7 4.0 9.9e-17 60.9 4.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69724.1 - 0.01 15.2 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX69724.1 - 0.14 12.2 0.9 3.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX69725.1 - 9.5e-39 133.3 4.9 1.4e-38 132.7 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX69725.1 - 0.13 12.7 0.8 0.61 10.6 0.2 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF4107 PF13389.6 EAX69726.1 - 1.1e-71 240.3 3.7 1.6e-71 239.7 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Mlf1IP PF10248.9 EAX69727.1 - 5.4e-12 46.0 2.7 5.4e-12 46.0 2.7 2.5 2 1 1 3 3 3 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ribosomal_60s PF00428.19 EAX69727.1 - 0.63 10.7 22.8 0.81 10.3 7.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ORC_WH_C PF18137.1 EAX69727.1 - 0.95 9.5 17.8 0.23 11.5 4.4 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal CDC27 PF09507.10 EAX69727.1 - 0.97 8.7 32.7 1.2 8.4 32.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_D5 PF03288.16 EAX69728.1 - 4.3e-05 23.9 2.3 0.0002 21.8 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX69728.1 - 0.044 14.4 0.1 0.091 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX69728.1 - 0.048 12.7 1.2 0.065 12.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX69728.1 - 0.08 12.9 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Peptidase_S64 PF08192.11 EAX69729.1 - 0.2 10.1 0.1 0.19 10.2 0.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Amidase02_C PF12123.8 EAX69731.1 - 0.0057 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX69732.1 - 5.1e-05 22.8 4.9 8.9e-05 22.1 4.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69732.1 - 0.0026 17.8 1.2 0.0045 17.0 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69732.1 - 0.011 15.3 0.3 0.023 14.3 0.3 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX69732.1 - 0.025 14.9 0.9 0.091 13.1 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) PSP PF04046.16 EAX69733.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP HR1 PF02185.16 EAX69735.1 - 0.0017 18.4 3.9 0.011 15.8 3.9 2.2 1 1 0 1 1 1 1 Hr1 repeat Exonuc_VII_L PF02601.15 EAX69735.1 - 0.0086 15.7 0.2 0.01 15.5 0.2 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit Fez1 PF06818.15 EAX69735.1 - 0.0096 16.4 3.6 0.011 16.2 3.6 1.1 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 EAX69735.1 - 0.029 14.4 5.0 0.029 14.4 5.0 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 EAX69735.1 - 0.033 12.2 0.0 0.035 12.1 0.0 1.0 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 EAX69735.1 - 0.044 13.8 1.9 0.083 12.9 1.9 1.5 1 0 0 1 1 1 0 Laminin Domain II YabA PF06156.13 EAX69735.1 - 0.045 14.4 0.5 0.067 13.8 0.5 1.3 1 0 0 1 1 1 0 Initiation control protein YabA MIP-T3_C PF17749.1 EAX69735.1 - 0.16 11.9 7.4 1.4 8.9 2.7 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Atg14 PF10186.9 EAX69735.1 - 0.19 10.8 2.3 0.19 10.8 2.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 EAX69735.1 - 0.3 11.6 5.7 0.61 10.6 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 PEARLI-4 PF05278.12 EAX69735.1 - 0.37 10.3 7.6 0.53 9.8 7.6 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) SlyX PF04102.12 EAX69735.1 - 0.44 11.2 4.0 0.92 10.2 4.0 1.6 1 1 0 1 1 1 0 SlyX DUF3552 PF12072.8 EAX69735.1 - 0.48 9.8 15.2 0.62 9.4 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HIP1_clath_bdg PF16515.5 EAX69735.1 - 0.64 10.7 8.2 0.98 10.1 8.2 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 EAX69735.1 - 1.9 7.7 4.7 2.4 7.3 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 EAX69735.1 - 3.9 7.5 10.8 5.4 7.1 10.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4106 PF13388.6 EAX69736.1 - 3.1e-232 771.2 19.8 3.5e-232 771.0 19.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX69736.1 - 0.00047 20.4 0.1 0.024 14.9 0.2 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated Mito_fiss_reg PF05308.11 EAX69739.1 - 0.04 14.0 1.2 0.043 13.9 1.2 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69739.1 - 0.58 9.6 5.7 0.6 9.6 5.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX69740.1 - 8.7e-138 457.6 13.0 2.6e-137 456.0 13.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69740.1 - 0.86 10.1 5.5 2.7 8.5 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ResIII PF04851.15 EAX69742.1 - 4.3e-05 23.6 2.6 7.9e-05 22.7 2.6 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX69742.1 - 0.00035 20.8 0.0 0.00058 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX69742.1 - 0.00057 19.7 0.0 0.00077 19.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69742.1 - 0.00077 19.3 0.8 0.0024 17.7 0.8 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69742.1 - 0.0067 16.8 0.0 0.009 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69742.1 - 0.027 14.2 0.2 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX69742.1 - 0.04 13.4 0.0 0.082 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX69742.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX69742.1 - 0.22 11.8 4.7 4.5 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX69742.1 - 0.25 11.0 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2207 PF09972.9 EAX69743.1 - 0.0011 17.8 0.7 0.0012 17.7 0.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 EAX69743.1 - 0.0021 17.5 5.0 0.0023 17.4 5.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RIFIN PF02009.16 EAX69743.1 - 0.0076 16.2 2.8 0.0097 15.8 2.8 1.0 1 0 0 1 1 1 1 Rifin Amnionless PF14828.6 EAX69743.1 - 0.025 13.4 0.4 0.031 13.1 0.4 1.2 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.6 EAX69743.1 - 0.047 13.5 1.2 0.053 13.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 EAX69743.1 - 0.22 11.8 2.7 0.29 11.4 2.6 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF3357 PF11837.8 EAX69743.1 - 0.24 11.9 0.8 0.42 11.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Ald_Xan_dh_C PF01315.22 EAX69743.1 - 0.36 11.2 4.2 0.6 10.5 4.2 1.3 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Sigma_reg_N PF13800.6 EAX69743.1 - 0.96 9.8 5.0 2.5 8.4 5.0 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ETRAMP PF09716.10 EAX69743.1 - 0.97 9.5 6.8 1.3 9.1 6.8 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pox_A32 PF04665.12 EAX69744.1 - 1.8e-07 30.9 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Amidase02_C PF12123.8 EAX69746.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69746.1 - 0.22 11.4 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX69747.1 - 3.3e-79 265.8 10.2 4.3e-79 265.4 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX69747.1 - 0.015 15.8 0.3 0.019 15.4 0.3 1.2 1 0 0 1 1 1 0 Fez1 Val_tRNA-synt_C PF10458.9 EAX69747.1 - 0.046 14.0 0.5 0.14 12.5 0.5 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm KilA-N PF04383.13 EAX69749.1 - 1.6e-43 147.1 0.6 3.2e-43 146.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69749.1 - 0.023 15.3 0.0 0.064 13.9 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family IstB_IS21 PF01695.17 EAX69751.1 - 2e-05 24.4 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69751.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX69751.1 - 3.3e-05 23.5 1.9 3.3e-05 23.5 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX69751.1 - 0.00054 20.0 5.4 0.00069 19.7 4.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69751.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69751.1 - 0.0028 17.5 1.6 0.0047 16.8 0.7 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69751.1 - 0.0034 17.1 2.6 0.0096 15.6 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69751.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX69751.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69751.1 - 0.076 13.4 0.1 0.72 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX69751.1 - 0.078 13.0 0.8 1.2 9.2 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX69751.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69751.1 - 0.43 10.9 4.5 8.6 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX69751.1 - 4.7 7.9 11.3 0.37 11.5 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Pox_D5 PF03288.16 EAX69752.1 - 0.00012 22.5 2.3 0.00059 20.3 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX69753.1 - 1e-64 216.7 6.7 1.2e-64 216.6 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX69753.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Btz PF09405.10 EAX69754.1 - 0.49 10.7 6.9 0.47 10.7 6.9 1.0 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF4106 PF13388.6 EAX69755.1 - 5.3e-238 790.2 15.2 6e-238 790.0 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX69755.1 - 0.01 16.1 0.1 0.45 10.8 0.2 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX69755.1 - 0.02 14.7 0.2 0.041 13.7 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF2939 PF11159.8 EAX69756.1 - 0.034 14.5 0.3 0.046 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX69756.1 - 1.6 9.4 4.8 2.8 8.6 4.8 1.5 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69757.1 - 0.038 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF5301 PF17225.3 EAX69757.1 - 0.18 12.2 3.4 0.15 12.5 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) Trypan_PARP PF05887.11 EAX69759.1 - 0.011 15.7 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX69759.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69760.1 - 0.064 13.1 0.9 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2897 PF11446.8 EAX69765.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Lectin_legB PF00139.19 EAX69766.1 - 0.0011 18.5 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX69766.1 - 0.0012 19.3 0.4 0.0038 17.7 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX69766.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3148 PF11347.8 EAX69766.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) C2-C2_1 PF11618.8 EAX69767.1 - 0.018 15.1 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 PTR PF12789.7 EAX69768.1 - 2.1e-05 24.5 0.6 2.1e-05 24.5 0.6 3.1 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX69768.1 - 0.0053 16.1 0.2 0.0084 15.4 0.2 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 1 EDR1 PF14381.6 EAX69768.1 - 0.014 15.1 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF445 PF04286.12 EAX69768.1 - 0.015 15.1 0.6 0.021 14.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX69768.1 - 0.043 14.3 0.3 0.17 12.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX69768.1 - 0.11 12.1 4.4 0.23 11.0 4.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX69770.1 - 3.2e-07 30.1 3.1 4.7e-07 29.5 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69770.1 - 0.0045 16.7 0.2 0.0058 16.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69770.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69770.1 - 0.063 13.0 0.1 0.27 11.0 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein APG12 PF04110.13 EAX69770.1 - 0.25 11.8 2.5 0.34 11.3 1.2 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3783 PF12646.7 EAX69770.1 - 0.25 11.3 2.2 1.3 9.0 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX69770.1 - 0.53 10.5 9.5 5.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF2939 PF11159.8 EAX69771.1 - 0.017 15.5 0.4 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69771.1 - 2.3 8.2 5.5 2.4 8.1 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX69772.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69772.1 - 0.027 14.5 0.6 0.038 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol_B_2 PF03175.13 EAX69773.1 - 5.1e-10 38.8 1.5 9.9e-10 37.9 1.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4106 PF13388.6 EAX69774.1 - 1.5e-200 666.8 16.9 1.9e-200 666.4 16.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX69774.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3839 PF12943.7 EAX69775.1 - 2.1e-138 459.6 11.2 2.3e-138 459.5 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69775.1 - 0.048 14.1 3.2 1.1 9.7 0.5 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX69776.1 - 3.9e-120 399.8 15.8 4.8e-120 399.5 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX69776.1 - 0.0038 16.7 0.4 0.0098 15.3 0.1 1.7 1 1 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) NTP_transf_6 PF06042.11 EAX69776.1 - 0.031 14.1 0.6 0.11 12.3 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Aminotran_1_2 PF00155.21 EAX69776.1 - 0.055 12.6 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II KELK PF15796.5 EAX69776.1 - 0.083 13.4 3.7 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX69776.1 - 0.73 10.4 3.4 1.3 9.6 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) GPS2_interact PF15784.5 EAX69777.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69777.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX69778.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX69778.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX69779.1 - 4.1e-07 29.7 0.0 5.1e-07 29.4 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX69781.1 - 4.8e-07 29.5 5.0 1e-06 28.4 5.0 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69781.1 - 0.0041 16.8 0.1 0.0067 16.1 0.1 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69781.1 - 0.059 12.9 0.4 0.071 12.6 0.4 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69781.1 - 0.062 13.0 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2805 PF10985.8 EAX69781.1 - 0.12 12.7 3.2 0.52 10.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX69781.1 - 0.18 11.8 1.1 1.3 9.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) Gly_rich PF12810.7 EAX69782.1 - 2.5e-27 96.4 34.3 2.9e-27 96.2 34.3 1.0 1 0 0 1 1 1 1 Glycine rich protein DNA_pol_B_2 PF03175.13 EAX69783.1 - 3.5e-23 82.2 10.4 1e-22 80.6 10.4 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral FAS_N PF17828.1 EAX69784.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX69784.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX69785.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69785.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX69785.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Amidase02_C PF12123.8 EAX69786.1 - 0.0019 17.9 0.0 0.0055 16.4 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69786.1 - 0.15 11.9 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX69787.1 - 7.7e-46 156.2 0.8 8.5e-46 156.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX69787.1 - 0.055 13.8 0.1 0.085 13.2 0.1 1.3 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX69788.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX69792.1 - 1.3e-24 86.9 11.8 5.2e-24 84.9 11.8 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX69792.1 - 0.089 12.8 0.0 0.91 9.5 0.0 2.5 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAX69794.1 - 5e-61 204.8 8.2 5.6e-61 204.7 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX69795.1 - 0.7 9.8 2.7 1.5 8.8 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX69796.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX69796.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX69797.1 - 7.5e-25 87.8 4.5 1.2e-24 87.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX69797.1 - 0.06 13.7 1.2 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX69797.1 - 0.18 12.3 1.5 0.66 10.5 0.3 2.0 1 1 0 2 2 2 0 Cell division protein ZapB DUF4108 PF13390.6 EAX69799.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX69801.1 - 1.1e-156 519.4 14.3 1.4e-156 519.1 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX69801.1 - 0.17 12.2 1.4 0.35 11.2 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX69801.1 - 6.2 7.3 7.5 5.4 7.5 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX69802.1 - 6.6e-34 116.1 0.3 2.2e-33 114.4 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX69802.1 - 0.26 9.8 0.1 0.35 9.4 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMP PF05017.14 EAX69803.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX69804.1 - 0.048 14.1 0.2 0.089 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX69805.1 - 1.1e-35 121.8 0.1 2.3e-35 120.8 0.0 1.6 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69805.1 - 0.0049 17.5 0.0 0.009 16.6 0.0 1.4 1 0 0 1 1 1 1 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX69807.1 - 1.9e-20 73.2 4.7 3.3e-20 72.4 4.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69807.1 - 0.053 12.8 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein HTH_32 PF13565.6 EAX69809.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TMP PF05017.14 EAX69811.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4460 PF14687.6 EAX69812.1 - 0.035 14.2 0.3 0.078 13.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DNA_pol_B_2 PF03175.13 EAX69813.1 - 9.4e-22 77.5 3.8 1.3e-21 77.0 3.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX69814.1 - 7e-08 32.2 0.9 7.8e-08 32.1 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69814.1 - 0.003 17.2 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69814.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69814.1 - 0.089 12.8 0.3 0.7 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX69814.1 - 0.13 12.7 1.4 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Amidase02_C PF12123.8 EAX69816.1 - 0.0036 16.9 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TPR_MLP1_2 PF07926.12 EAX69817.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX69817.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX69817.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3384 PF11864.8 EAX69818.1 - 0.00091 18.2 0.3 0.001 18.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) NopRA1 PF16201.5 EAX69818.1 - 0.0043 16.7 0.3 0.007 16.0 0.3 1.3 1 1 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 DUF3500 PF12006.8 EAX69818.1 - 0.12 11.8 0.2 0.15 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF4359 PF14271.6 EAX69818.1 - 0.16 12.7 2.7 0.2 12.4 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) DUF4106 PF13388.6 EAX69819.1 - 7.9e-200 664.4 16.8 9.6e-200 664.2 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX69819.1 - 0.0067 16.7 0.1 0.42 10.9 0.2 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX69819.1 - 0.1 13.2 0.7 0.25 12.0 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit DUF3839 PF12943.7 EAX69820.1 - 5.3e-40 137.4 3.9 7.2e-40 137.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2897 PF11446.8 EAX69821.1 - 1.8 8.5 3.7 3.7 7.5 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69822.1 - 4.6e-43 146.6 3.0 5e-43 146.4 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX69822.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF4108 PF13390.6 EAX69823.1 - 2.9e-62 208.8 8.3 3.2e-62 208.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX69823.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GPS2_interact PF15784.5 EAX69824.1 - 0.0076 16.7 0.7 0.01 16.2 0.7 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69824.1 - 0.094 11.7 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX69825.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69825.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX69825.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX69825.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX69826.1 - 3.2e-62 208.7 5.7 3.5e-62 208.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FAS_N PF17828.1 EAX69828.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX69829.1 - 1.9e-09 37.5 19.0 0.21 11.7 3.5 4.2 3 2 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX69829.1 - 0.84 9.2 9.2 8.4 5.9 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX69830.1 - 7.3e-21 74.6 4.2 1.4e-20 73.6 4.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69830.1 - 0.044 13.1 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PTR PF12789.7 EAX69832.1 - 4.1e-10 39.5 17.6 1.1e-07 31.8 3.9 4.1 4 0 0 4 4 4 2 Phage tail repeat like Ribosomal_S4e PF00900.20 EAX69832.1 - 0.038 13.9 0.1 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Ribosomal family S4e LIFR_D2 PF17971.1 EAX69832.1 - 0.11 12.6 0.0 18 5.5 0.0 2.3 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX69832.1 - 0.12 12.3 0.5 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Interleukin 2 HD_2 PF12917.7 EAX69832.1 - 0.16 11.7 1.5 10 5.8 0.1 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme DUF4107 PF13389.6 EAX69833.1 - 2.2e-42 144.9 13.7 9.3e-41 139.7 13.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX69833.1 - 0.073 13.4 0.1 0.085 13.2 0.1 1.1 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4106 PF13388.6 EAX69835.1 - 1.2e-66 225.7 2.6 1.2e-66 225.7 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX69835.1 - 0.038 13.5 0.4 0.08 12.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) FTCD_C PF04961.12 EAX69835.1 - 1.6 8.4 4.6 3.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase PTR PF12789.7 EAX69836.1 - 3.5e-52 174.3 37.6 1.8e-34 117.6 16.8 5.6 3 3 3 6 6 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX69836.1 - 0.024 14.3 18.7 0.049 13.2 5.3 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX69836.1 - 0.024 15.2 3.1 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PH_TFIIH PF08567.11 EAX69836.1 - 1.1 9.7 4.6 18 5.7 0.2 3.6 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF4107 PF13389.6 EAX69837.1 - 2.4e-72 242.4 4.2 2.8e-72 242.1 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX69837.1 - 0.21 9.9 1.3 0.31 9.4 1.3 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1031 PF06275.11 EAX69838.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) TMP PF05017.14 EAX69839.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69840.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX69841.1 - 0.0065 16.1 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX69842.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Imm70 PF15601.6 EAX69843.1 - 0.37 10.3 40.6 23 4.5 0.2 10.5 1 1 17 18 18 18 0 Immunity protein 70 PTR PF12789.7 EAX69844.1 - 7e-48 160.5 29.6 7.1e-32 109.3 13.1 4.1 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX69844.1 - 0.028 14.2 1.0 0.053 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX69844.1 - 0.034 13.6 0.9 0.073 12.5 0.6 1.7 1 1 1 2 2 2 0 RRNA methyltransferase AviRa T5orf172 PF10544.9 EAX69845.1 - 3.2e-07 30.8 0.3 6.5e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4106 PF13388.6 EAX69846.1 - 3e-214 711.9 17.9 3.5e-214 711.7 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX69849.1 - 4.5e-156 517.5 12.9 5.5e-156 517.2 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69849.1 - 0.094 13.2 5.0 2 8.9 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX69851.1 - 3.8e-148 491.5 14.5 4.4e-148 491.3 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX69851.1 - 0.092 12.6 0.9 0.3 10.9 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX69851.1 - 0.33 11.4 4.2 1.1 9.7 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX69853.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX69855.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69855.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69855.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69855.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69855.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX69855.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX69855.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX69856.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69856.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX69856.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX69856.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX69856.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX69856.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX69856.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX69859.1 - 9e-21 73.8 1.2 1.5e-20 73.1 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX69860.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69860.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4106 PF13388.6 EAX69863.1 - 2.9e-30 105.9 3.1 2.9e-30 105.9 3.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) HlyD_2 PF12700.7 EAX69863.1 - 0.074 11.8 1.1 0.074 11.8 1.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF3839 PF12943.7 EAX69864.1 - 4.4e-83 278.5 3.7 4.9e-83 278.3 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX69864.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc binding domain DUF3839 PF12943.7 EAX69865.1 - 1.7e-28 99.7 7.0 2.5e-28 99.2 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX69866.1 - 2.5e-73 246.5 6.9 3.3e-73 246.1 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX69866.1 - 0.096 13.7 0.3 0.18 12.7 0.3 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DAGK_acc PF00609.19 EAX69867.1 - 6.9e-14 52.5 0.0 7.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain PTR PF12789.7 EAX69868.1 - 5.9e-62 205.6 43.7 9e-34 115.3 15.9 5.2 2 2 3 5 5 5 3 Phage tail repeat like RACo_linker PF17650.1 EAX69868.1 - 0.0057 16.5 0.1 0.8 9.6 0.1 3.2 2 1 0 2 2 2 1 RACo linker region PH_TFIIH PF08567.11 EAX69868.1 - 0.32 11.4 7.2 5.9 7.3 0.2 4.4 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF4404 PF14357.6 EAX69868.1 - 6.3 7.5 7.7 9.6 6.9 0.2 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) DUF4378 PF14309.6 EAX69869.1 - 0.00082 19.8 0.0 0.00087 19.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) MULE PF10551.9 EAX69870.1 - 0.032 14.6 2.5 0.11 13.0 0.1 3.0 3 1 1 4 4 4 0 MULE transposase domain DUF2960 PF11173.8 EAX69870.1 - 0.047 14.1 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) DUF3839 PF12943.7 EAX69871.1 - 5.4e-155 513.9 12.6 6.9e-155 513.6 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX69871.1 - 0.024 14.9 0.6 0.074 13.3 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX69871.1 - 3.9 8.0 7.2 1.9 9.0 0.6 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX69872.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat HC2 PF07382.11 EAX69874.1 - 4.1e-10 40.1 24.6 1.8e-09 37.9 24.6 1.8 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX69874.1 - 9.4e-07 28.9 3.0 6.4e-05 23.0 3.0 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) YvrJ PF12841.7 EAX69875.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Amidase02_C PF12123.8 EAX69877.1 - 0.0019 17.8 0.0 0.0059 16.3 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69877.1 - 0.16 11.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX69878.1 - 9.6e-15 54.4 1.3 1.9e-14 53.4 1.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX69878.1 - 0.0077 15.6 0.2 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX69878.1 - 0.054 13.5 0.8 0.54 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) PTR PF12789.7 EAX69879.1 - 3.8e-28 97.3 23.3 7.8e-22 77.1 7.4 4.8 3 1 1 4 4 4 3 Phage tail repeat like DUF4795 PF16043.5 EAX69879.1 - 0.38 10.3 13.8 1.3 8.6 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX69880.1 - 6.9e-07 29.0 2.6 6.9e-07 29.0 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69880.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69880.1 - 4.5e-05 23.3 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69880.1 - 0.00014 21.9 3.1 0.00035 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69880.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69880.1 - 0.0017 18.2 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69880.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69880.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69880.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69880.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69880.1 - 0.093 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69880.1 - 0.31 11.3 3.9 9.2 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GPS2_interact PF15784.5 EAX69881.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX69881.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX69882.1 - 4.3e-07 29.6 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ResIII PF04851.15 EAX69884.1 - 2.1e-05 24.6 0.5 3.2e-05 24.0 0.5 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69884.1 - 0.00028 20.7 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX69884.1 - 0.00043 20.6 0.0 0.00063 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX69884.1 - 0.0019 18.1 0.0 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69884.1 - 0.007 16.7 0.0 0.015 15.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69884.1 - 0.034 13.6 0.0 0.068 12.6 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX69884.1 - 0.063 12.9 0.3 0.097 12.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX69884.1 - 0.068 12.9 0.0 0.097 12.4 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX69884.1 - 0.095 12.3 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX69884.1 - 0.2 11.4 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FAS_N PF17828.1 EAX69885.1 - 0.0079 16.2 0.2 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69886.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69886.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX69887.1 - 7.9e-40 135.2 0.3 2.2e-39 133.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX69887.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) PTR PF12789.7 EAX69890.1 - 0.19 11.8 0.4 0.19 11.8 0.4 3.2 4 0 0 4 4 4 0 Phage tail repeat like FAS_N PF17828.1 EAX69891.1 - 0.0055 16.7 0.3 0.0073 16.3 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69892.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69892.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2939 PF11159.8 EAX69893.1 - 0.0093 16.4 0.4 0.011 16.1 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69893.1 - 4.1 7.4 5.7 4.3 7.3 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX69894.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX69894.1 - 0.043 13.8 0.5 0.062 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Ank_2 PF12796.7 EAX69895.1 - 1.7e-63 211.2 1.2 1.4e-18 67.3 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX69895.1 - 7.7e-48 160.3 0.8 1.7e-11 44.4 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX69895.1 - 5.4e-42 141.3 0.4 2.7e-11 43.5 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX69895.1 - 3.1e-36 122.3 0.0 2.5e-07 30.8 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX69895.1 - 9.7e-29 96.2 0.0 4e-06 26.8 0.0 5.2 6 0 0 6 6 6 4 Ankyrin repeat ENTH PF01417.20 EAX69895.1 - 0.00052 20.1 0.4 31 4.6 0.0 4.4 2 1 2 4 4 4 0 ENTH domain Pox_E8 PF03394.13 EAX69895.1 - 0.011 15.3 2.0 11 5.4 0.1 3.6 2 1 2 4 4 4 0 Poxvirus E8 protein DUF2795 PF11387.8 EAX69895.1 - 0.022 14.9 1.3 1.3e+02 2.9 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) DUF2689 PF10894.8 EAX69895.1 - 0.024 14.4 0.0 23 4.9 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2689) DUF1897 PF09005.10 EAX69895.1 - 0.027 14.0 0.1 70 3.0 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) Prismane PF03063.20 EAX69896.1 - 0.25 10.0 3.3 0.29 9.8 3.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family EpuA PF11772.8 EAX69897.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Apolipoprotein PF01442.18 EAX69898.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5588 PF17826.1 EAX69899.1 - 0.002 17.1 0.3 0.0026 16.7 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) SH3_14 PF18343.1 EAX69899.1 - 0.079 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Dda helicase SH3 domain GrpE PF01025.19 EAX69899.1 - 0.11 12.1 5.2 0.14 11.8 5.2 1.2 1 0 0 1 1 1 0 GrpE CTU2 PF10288.9 EAX69899.1 - 0.11 12.7 1.3 0.49 10.6 0.0 2.1 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4061 PF13270.6 EAX69899.1 - 0.19 12.0 3.6 0.26 11.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Fib_alpha PF08702.10 EAX69899.1 - 0.42 10.8 7.4 0.29 11.3 2.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family rve PF00665.26 EAX69900.1 - 5.3e-10 39.5 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX69900.1 - 0.00029 21.1 0.0 0.00082 19.6 0.0 1.8 1 0 0 1 1 1 1 DDE domain KilA-N PF04383.13 EAX69901.1 - 4e-23 81.4 0.3 5.9e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX69901.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMP PF05017.14 EAX69902.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat ResIII PF04851.15 EAX69904.1 - 0.039 13.9 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX69904.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX69905.1 - 1.3e-126 421.0 6.9 1.5e-126 420.8 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69905.1 - 0.12 12.9 1.2 1 9.9 0.4 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank PF00023.30 EAX69906.1 - 4.4e-29 99.6 1.5 1.1e-08 35.1 0.2 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX69906.1 - 1.6e-27 95.5 5.0 7.1e-14 52.0 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX69906.1 - 2.9e-27 95.0 5.2 1e-13 51.7 0.3 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX69906.1 - 7.4e-26 87.4 5.0 2e-07 30.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX69906.1 - 9.6e-17 60.8 1.4 5.7e-10 39.3 0.3 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX69906.1 - 0.087 12.8 2.4 0.47 10.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) HHH_7 PF14635.6 EAX69906.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif CEP44 PF15007.6 EAX69906.1 - 0.16 12.1 0.0 31 4.7 0.0 2.8 1 1 2 3 3 3 0 Centrosomal spindle body, CEP44 DUF2897 PF11446.8 EAX69907.1 - 1.6 8.7 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX69908.1 - 5.3e-63 211.2 6.5 5.9e-63 211.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX69909.1 - 1.4e-25 90.2 4.4 2.1e-25 89.6 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX69910.1 - 0.00024 21.6 0.4 0.0029 18.1 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX69910.1 - 0.0042 16.7 0.2 0.58 9.7 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX69910.1 - 0.057 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 KilA-N domain DUF3148 PF11347.8 EAX69910.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) CooT PF10133.9 EAX69911.1 - 0.09 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT T5orf172 PF10544.9 EAX69912.1 - 3.3e-07 30.8 1.2 7.2e-07 29.7 0.4 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX69912.1 - 0.0085 15.7 0.5 0.11 12.0 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX69912.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX69912.1 - 0.11 12.4 0.7 0.36 10.7 0.2 2.2 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX69915.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX69915.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4795 PF16043.5 EAX69916.1 - 0.024 14.3 0.7 0.032 13.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX69916.1 - 0.67 10.3 4.4 9 6.8 0.2 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF4841 PF16129.5 EAX69917.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) Amidase02_C PF12123.8 EAX69918.1 - 0.0013 18.4 0.1 0.0032 17.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX69919.1 - 6e-07 29.2 2.7 6e-07 29.2 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69919.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69919.1 - 5.2e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69919.1 - 0.00012 22.1 2.9 0.00028 20.9 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69919.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69919.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69919.1 - 0.0019 17.9 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69919.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69919.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69919.1 - 0.089 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69919.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69919.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX69920.1 - 4.1e-31 106.8 27.6 7.5e-24 83.6 7.8 4.4 3 1 1 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX69920.1 - 0.032 14.0 0.1 0.096 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) CppA_C PF14507.6 EAX69920.1 - 0.84 10.4 7.5 1.5 9.6 0.4 3.4 3 1 0 3 3 3 0 CppA C-terminal DDE_1 PF03184.19 EAX69921.1 - 1.1e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_B_2 PF03175.13 EAX69922.1 - 3.3e-11 42.7 1.8 1.6e-10 40.5 1.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX69922.1 - 0.0033 16.2 1.0 0.2 10.3 0.8 2.9 2 1 0 2 2 2 1 DNA polymerase family B DUF5106 PF17127.4 EAX69922.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) ANAPC4_WD40 PF12894.7 EAX69923.1 - 0.0032 17.7 0.0 7.6 6.9 0.0 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMtag PF10159.9 EAX69923.1 - 0.22 11.8 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 Multiple myeloma tumor-associated TMP PF05017.14 EAX69924.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX69925.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Tho2 PF11262.8 EAX69926.1 - 0.28 10.3 3.7 0.31 10.2 3.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Amidase02_C PF12123.8 EAX69927.1 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX69927.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Gly-zipper_Omp PF13488.6 EAX69929.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX69929.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX69929.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2897 PF11446.8 EAX69930.1 - 1.1 9.2 3.8 2.4 8.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX69932.1 - 1.4e-157 522.4 12.8 1.7e-157 522.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69932.1 - 0.071 13.6 7.4 0.82 10.2 0.5 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX69932.1 - 0.088 13.2 0.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX69932.1 - 1.7 9.0 5.9 13 6.1 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal TMP PF05017.14 EAX69934.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX69937.1 - 2.5e-37 126.7 27.6 9e-29 99.3 14.9 4.0 4 2 1 5 5 5 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX69937.1 - 0.0051 17.1 5.0 2.1 8.7 0.1 3.6 1 1 2 3 3 3 2 TFIIH p62 subunit, N-terminal domain DUF2203 PF09969.9 EAX69937.1 - 0.015 16.0 3.4 2.2 9.0 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4116 PF13475.6 EAX69937.1 - 0.022 14.5 0.1 0.061 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Phage_TTP_12 PF16461.5 EAX69937.1 - 0.24 11.1 4.9 0.12 12.1 1.1 2.3 2 1 0 2 2 2 0 Lambda phage tail tube protein, TTP YodL PF14191.6 EAX69937.1 - 0.69 10.8 4.3 11 6.9 0.1 3.3 2 1 2 4 4 4 0 YodL-like DUF4107 PF13389.6 EAX69939.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX69939.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TbpB_A PF17484.2 EAX69940.1 - 1.6 9.5 6.8 3.1 8.6 6.8 1.6 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B ACP_PD PF04336.12 EAX69941.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase nsp7 PF08716.10 EAX69942.1 - 0.13 12.9 2.0 8.9 7.0 0.1 2.8 2 0 0 2 2 2 0 nsp7 replicase PTR PF12789.7 EAX69943.1 - 9.2e-54 179.4 36.5 6.4e-35 119.0 16.2 3.1 2 1 1 3 3 3 2 Phage tail repeat like Apolipoprotein PF01442.18 EAX69943.1 - 0.14 12.0 0.7 0.21 11.4 0.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PH_TFIIH PF08567.11 EAX69943.1 - 2.4 8.5 4.8 34 4.9 0.1 3.9 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain Pox_D5 PF03288.16 EAX69944.1 - 7.9e-05 23.1 3.3 0.00049 20.5 3.3 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX69944.1 - 0.087 12.8 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX69945.1 - 6.6e-60 201.2 8.7 7.3e-60 201.0 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX69946.1 - 4.7e-07 29.5 2.2 4.7e-07 29.5 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX69946.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX69946.1 - 8.1e-05 22.4 0.2 0.36 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX69946.1 - 0.00013 22.0 3.1 0.00029 20.9 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69946.1 - 0.00059 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69946.1 - 0.0016 18.3 0.8 0.0031 17.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69946.1 - 0.002 17.8 0.6 0.012 15.2 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69946.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69946.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69946.1 - 0.088 13.2 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69946.1 - 0.089 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX69946.1 - 0.32 11.3 3.9 8.7 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX69947.1 - 6.3e-08 32.4 1.4 1e-07 31.7 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5446 PF17522.2 EAX69948.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PTR PF12789.7 EAX69949.1 - 2e-105 344.8 74.2 8.5e-35 118.6 16.3 5.9 2 2 4 6 6 5 4 Phage tail repeat like DUF4116 PF13475.6 EAX69949.1 - 0.016 14.9 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX69949.1 - 0.34 10.7 10.9 5.3 6.8 7.4 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) ResIII PF04851.15 EAX69952.1 - 2.3e-05 24.5 0.1 3.1e-05 24.0 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69952.1 - 0.0004 20.2 0.0 0.0005 19.9 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69952.1 - 0.0015 18.4 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX69952.1 - 0.0017 18.7 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX69952.1 - 0.0051 17.2 0.0 0.0071 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX69952.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX69952.1 - 0.059 13.1 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX69952.1 - 0.066 12.8 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX69952.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2939 PF11159.8 EAX69956.1 - 0.01 16.3 0.5 0.012 16.0 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69956.1 - 1.3 8.0 2.6 1.3 8.0 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69956.1 - 1.4 8.9 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX69957.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX69958.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX69960.1 - 0.085 11.8 0.1 0.088 11.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX69960.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX69961.1 - 7.9e-05 22.2 2.3 7.9e-05 22.2 2.3 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX69961.1 - 0.006 16.6 0.7 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX69961.1 - 0.0094 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX69961.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4107 PF13389.6 EAX69962.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX69962.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX69963.1 - 4.8e-40 135.9 0.6 1e-39 134.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69963.1 - 0.041 14.5 0.0 0.085 13.5 0.0 1.5 1 0 0 1 1 1 0 Parathyroid hormone family VirE PF05272.11 EAX69964.1 - 0.021 14.6 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E RNA_helicase PF00910.22 EAX69964.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX69964.1 - 0.096 11.6 0.2 8.7 5.1 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF3839 PF12943.7 EAX69965.1 - 1.2e-159 529.2 13.0 1.4e-159 528.9 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX69965.1 - 7.6 7.1 9.2 2.4 8.7 0.9 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX69967.1 - 5.6e-13 48.7 13.6 2.1e-08 34.1 0.5 3.7 4 0 0 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX69967.1 - 0.024 14.4 0.1 0.073 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX69967.1 - 0.035 13.8 3.4 0.68 9.6 0.6 2.9 2 1 1 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX69967.1 - 0.036 14.5 6.4 0.095 13.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) NPV_P10 PF05531.12 EAX69967.1 - 3.3 8.2 14.7 8 7.0 0.0 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2960 PF11173.8 EAX69968.1 - 0.023 15.1 0.3 0.057 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX69968.1 - 0.038 14.0 3.1 0.12 12.4 0.4 2.6 2 1 1 3 3 3 0 YpjP-like protein PTR PF12789.7 EAX69969.1 - 2.3e-09 37.1 9.3 1.5e-08 34.6 1.0 3.9 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX69969.1 - 0.053 13.1 10.9 0.46 10.0 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF5017 PF16409.5 EAX69969.1 - 0.093 12.2 2.5 1.2 8.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) Phage_fiber PF03335.13 EAX69969.1 - 1.8 8.9 15.2 3.6 8.0 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX69972.1 - 4.5e-10 39.4 9.3 1.1e-08 35.0 5.6 4.3 5 0 0 5 5 5 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX69972.1 - 0.075 13.2 0.0 8.4 6.6 0.0 2.3 1 1 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX69972.1 - 0.34 10.9 3.7 7.6 6.5 0.1 2.8 2 1 1 3 3 3 0 Interleukin 2 EMP24_GP25L PF01105.24 EAX69972.1 - 0.48 10.3 5.1 11 6.0 1.3 3.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF5082 PF16888.5 EAX69972.1 - 6.6 7.0 8.2 5.5 7.3 2.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) PSP PF04046.16 EAX69973.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX69974.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX69976.1 - 2.5e-28 98.2 0.1 2.5e-28 98.2 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX69976.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Amidase02_C PF12123.8 EAX69977.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Meiosis_expr PF15163.6 EAX69978.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX69978.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX69978.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family FAS_N PF17828.1 EAX69979.1 - 0.0082 16.2 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX69980.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX69980.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2939 PF11159.8 EAX69982.1 - 0.028 14.8 0.3 0.038 14.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69982.1 - 0.68 8.9 1.9 0.74 8.8 1.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69982.1 - 2.2 8.3 4.6 2.3 8.2 4.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX69983.1 - 5.7e-40 137.3 5.2 7.8e-40 136.8 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX69983.1 - 0.33 11.0 3.1 2.6 8.2 1.2 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pox_A32 PF04665.12 EAX69984.1 - 8.2e-08 32.0 0.5 8.4e-08 32.0 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX69984.1 - 0.0075 15.9 0.1 0.0079 15.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX69984.1 - 0.055 13.4 0.4 0.51 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX69984.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2939 PF11159.8 EAX69985.1 - 0.039 14.4 0.4 0.054 13.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX69985.1 - 1.5 9.5 4.8 2.6 8.7 4.8 1.5 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX69986.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX69986.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal PTR PF12789.7 EAX69987.1 - 6.2e-25 87.0 17.6 4.8e-17 61.8 1.9 3.9 3 1 1 4 4 4 2 Phage tail repeat like UPF0242 PF06785.11 EAX69987.1 - 0.17 12.0 4.6 0.25 11.5 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CppA_C PF14507.6 EAX69987.1 - 0.32 11.7 3.3 0.65 10.8 0.3 2.4 2 0 0 2 2 2 0 CppA C-terminal RNA12 PF10443.9 EAX69987.1 - 5.7 5.6 11.0 27 3.3 11.0 1.8 1 1 0 1 1 1 0 RNA12 protein PTR PF12789.7 EAX69988.1 - 4.5e-10 39.4 23.0 2.8e-09 36.9 1.7 4.7 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX69988.1 - 0.0033 17.1 13.7 0.16 11.6 2.8 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Amidase02_C PF12123.8 EAX69990.1 - 0.14 11.9 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF2939 PF11159.8 EAX69991.1 - 0.063 13.7 0.4 0.085 13.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69991.1 - 1.2 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX69991.1 - 1.5 8.8 5.5 1.6 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX69992.1 - 0.036 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX69992.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mito_fiss_reg PF05308.11 EAX69994.1 - 0.091 12.8 0.3 0.095 12.8 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX69994.1 - 0.4 10.1 1.7 0.4 10.1 1.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2939 PF11159.8 EAX69995.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX69995.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX69995.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX69995.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX69996.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX69997.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX69998.1 - 4.3e-07 29.6 1.9 4.3e-07 29.6 1.9 2.0 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX69998.1 - 3.2e-05 23.7 0.3 0.34 10.6 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX69998.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX69998.1 - 0.00022 21.3 3.5 0.0005 20.1 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX69998.1 - 0.00065 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX69998.1 - 0.0022 17.8 1.1 0.0045 16.8 0.9 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX69998.1 - 0.0035 17.0 2.0 0.012 15.3 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX69998.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX69998.1 - 0.085 12.4 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX69998.1 - 0.099 13.1 0.1 0.9 10.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX69998.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF573 PF04504.14 EAX69998.1 - 0.28 11.9 10.6 0.19 12.4 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX69998.1 - 0.52 10.6 4.3 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX69999.1 - 2.8e-32 110.9 1.8 4e-32 110.4 0.3 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX69999.1 - 0.0067 17.0 0.6 0.017 15.7 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family Amidase02_C PF12123.8 EAX70000.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX70004.1 - 2.5e-231 768.2 16.5 3e-231 767.9 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX70004.1 - 0.022 14.6 0.2 0.047 13.5 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX70004.1 - 0.1 12.6 14.6 0.15 12.0 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PapD_N PF00345.20 EAX70006.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70006.1 - 0.084 12.9 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX70006.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PSP PF04046.16 EAX70009.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70010.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX70012.1 - 9.2e-148 492.9 20.2 1.4e-147 492.3 20.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) PapD_N PF00345.20 EAX70013.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70013.1 - 0.057 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX70014.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70014.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70014.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70014.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70014.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70014.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Trypan_PARP PF05887.11 EAX70015.1 - 0.097 12.7 4.3 0.12 12.4 4.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX70016.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX70018.1 - 1.5e-67 227.6 4.5 2e-67 227.2 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX70019.1 - 0.00086 19.8 1.0 0.0021 18.5 0.2 1.9 2 0 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX70019.1 - 0.013 14.8 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 RFX_DNA_binding PF02257.15 EAX70022.1 - 0.00014 22.4 0.1 0.0002 21.9 0.1 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX70022.1 - 0.0011 19.4 1.7 0.0018 18.8 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX70022.1 - 0.051 13.6 0.9 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Pox_D5 PF03288.16 EAX70023.1 - 7.5e-05 23.1 3.1 0.00047 20.6 3.1 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70023.1 - 0.086 13.5 0.1 0.18 12.5 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Trypan_PARP PF05887.11 EAX70024.1 - 0.098 12.6 6.8 0.16 12.0 6.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX70025.1 - 7.8e-79 264.5 9.6 1e-78 264.1 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) AAA_22 PF13401.6 EAX70026.1 - 2.8e-05 24.4 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70026.1 - 3e-05 23.6 1.9 3e-05 23.6 1.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX70026.1 - 9.9e-05 22.1 0.2 0.31 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70026.1 - 0.00034 20.7 4.3 0.00058 19.9 3.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70026.1 - 0.00055 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70026.1 - 0.0011 18.8 0.5 0.0029 17.4 0.5 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70026.1 - 0.0029 17.3 2.6 0.0096 15.6 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70026.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX70026.1 - 0.062 12.9 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX70026.1 - 0.064 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX70026.1 - 0.079 13.4 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70026.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF573 PF04504.14 EAX70026.1 - 3.3 8.4 10.7 0.2 12.3 1.4 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF2897 PF11446.8 EAX70027.1 - 0.2 11.5 3.2 0.4 10.6 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70028.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF257 PF03192.13 EAX70029.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX70029.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p VirE PF05272.11 EAX70030.1 - 1.4e-05 25.0 0.1 2.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX70030.1 - 0.089 13.2 0.2 0.3 11.5 0.1 2.0 1 1 1 2 2 2 0 RNA helicase RRM_9 PF18444.1 EAX70031.1 - 0.014 15.2 0.1 5.7 6.9 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif Fungal_trans PF04082.18 EAX70031.1 - 0.66 8.9 5.0 4.6 6.2 0.3 2.0 1 1 1 2 2 2 0 Fungal specific transcription factor domain zf-H3C2 PF16721.5 EAX70031.1 - 1.8 9.0 5.3 14 6.1 0.6 2.1 1 1 1 2 2 2 0 Zinc-finger like, probable DNA-binding DUF3447 PF11929.8 EAX70032.1 - 1.6e-34 117.7 6.0 1.6e-34 117.7 6.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX70032.1 - 2.4e-05 24.8 0.1 0.00029 21.3 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Amidase02_C PF12123.8 EAX70035.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX70037.1 - 0.0096 15.9 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4140 PF13600.6 EAX70037.1 - 0.12 12.9 1.4 0.15 12.5 1.4 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BRO1 PF03097.18 EAX70038.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Pox_A32 PF04665.12 EAX70039.1 - 5.8e-08 32.5 1.3 7.3e-08 32.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70039.1 - 0.0041 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70039.1 - 0.046 13.4 0.1 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70039.1 - 0.071 13.1 0.4 0.63 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) TMP PF05017.14 EAX70040.1 - 0.072 13.7 4.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70041.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX70042.1 - 3.5e-07 30.0 0.2 3.5e-07 30.0 0.2 2.3 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX70042.1 - 0.007 16.5 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX70042.1 - 0.18 10.3 0.2 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) PapD_N PF00345.20 EAX70043.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70043.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_32 PF13565.6 EAX70045.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Pox_A32 PF04665.12 EAX70046.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70046.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX70046.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX70046.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70046.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX70046.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DNA_pol_B_2 PF03175.13 EAX70047.1 - 7.2e-21 74.6 5.5 1.4e-20 73.7 5.5 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral BRO1 PF03097.18 EAX70048.1 - 0.036 12.9 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF3839 PF12943.7 EAX70049.1 - 8.9e-156 516.5 13.2 1.1e-155 516.1 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70049.1 - 0.14 12.0 0.7 0.43 10.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX70049.1 - 0.21 11.9 1.1 0.52 10.7 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX70049.1 - 0.28 11.8 4.1 1.2 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX70050.1 - 0.02 15.4 0.8 0.041 14.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX70051.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70051.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70051.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70051.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70051.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70051.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70051.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) TubC_N PF18563.1 EAX70052.1 - 0.11 12.5 0.1 17 5.5 0.0 2.4 2 1 0 2 2 2 0 TubC N-terminal docking domain DUF659 PF04937.15 EAX70053.1 - 0.0078 16.1 0.1 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Amidase02_C PF12123.8 EAX70056.1 - 0.004 16.8 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX70057.1 - 6.3e-71 237.8 3.4 8.2e-71 237.4 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) La PF05383.17 EAX70058.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 La domain PAXIP1_C PF15364.6 EAX70059.1 - 0.019 15.3 0.3 0.023 15.0 0.3 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4107 PF13389.6 EAX70061.1 - 1.1e-61 207.7 2.8 1.5e-61 207.3 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX70062.1 - 2.8e-151 501.8 15.0 3.4e-151 501.5 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX70062.1 - 0.056 13.9 2.2 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX70062.1 - 0.23 11.3 2.0 0.55 10.1 0.4 2.0 1 1 0 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX70062.1 - 0.31 11.4 3.3 0.64 10.3 0.1 2.9 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX70062.1 - 0.78 10.2 5.8 4.8 7.7 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX70063.1 - 1.4e-05 25.5 0.1 3.3e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX70064.1 - 6e-08 32.4 1.4 1e-07 31.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX70064.1 - 0.045 14.1 0.1 0.075 13.3 0.1 1.5 1 1 0 1 1 1 0 PRD domain RskA PF10099.9 EAX70068.1 - 0.03 14.6 0.3 0.031 14.6 0.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 EAX70068.1 - 2.8 7.9 4.2 2.8 7.9 4.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HTH_32 PF13565.6 EAX70068.1 - 3.4 8.3 5.4 14 6.4 5.4 1.8 1 1 0 1 1 1 0 Homeodomain-like domain KIAA1430 PF13879.6 EAX70069.1 - 0.013 16.3 2.0 0.019 15.7 2.0 1.3 1 0 0 1 1 1 0 KIAA1430 homologue Ribosomal_60s PF00428.19 EAX70069.1 - 3.3 8.3 6.0 0.33 11.6 0.8 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein KilA-N PF04383.13 EAX70070.1 - 9.5e-40 134.9 0.0 1.8e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX70070.1 - 0.01 16.4 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family PTR PF12789.7 EAX70071.1 - 1.2e-31 108.5 26.3 1.6e-31 108.1 14.6 4.0 2 2 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX70071.1 - 0.018 14.7 1.1 0.038 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX70072.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX70073.1 - 1.1e-138 460.6 10.5 1.2e-138 460.4 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX70073.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.2 3 0 0 3 3 3 0 Zinc binding domain zf-C4pol PF14260.6 EAX70073.1 - 1.7 9.1 5.8 5.3 7.6 0.2 2.9 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX70073.1 - 3.1 8.3 9.5 1.6 9.2 1.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase IstB_IS21 PF01695.17 EAX70074.1 - 2.3e-05 24.2 0.4 0.27 11.0 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70074.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70074.1 - 7.1e-05 22.4 2.3 7.1e-05 22.4 2.3 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX70074.1 - 0.00031 20.8 4.8 0.00049 20.1 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70074.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70074.1 - 0.0015 18.4 1.0 0.0031 17.4 0.5 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70074.1 - 0.004 16.8 2.8 0.014 15.0 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70074.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX70074.1 - 0.06 13.4 0.6 0.95 9.5 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX70074.1 - 0.067 12.8 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70074.1 - 0.072 13.5 0.1 0.7 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70074.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70074.1 - 0.31 11.3 5.2 3.5 7.9 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70074.1 - 5.1 7.8 11.0 0.35 11.6 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DNA_pol_B_2 PF03175.13 EAX70075.1 - 6.3e-23 81.4 4.9 1.1e-22 80.6 4.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70075.1 - 0.056 12.8 0.2 0.087 12.1 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX70075.1 - 0.32 11.1 2.8 13 5.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) GPS2_interact PF15784.5 EAX70076.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70076.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX70077.1 - 0.056 13.4 9.3 0.07 13.1 9.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX70077.1 - 4 5.0 14.7 5.1 4.6 14.7 1.2 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX70077.1 - 7.7 7.0 6.7 12 6.4 6.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX70078.1 - 6.2e-07 29.1 2.7 6.2e-07 29.1 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70078.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70078.1 - 6.6e-05 22.7 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70078.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70078.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70078.1 - 0.0012 18.6 0.6 0.0023 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70078.1 - 0.0018 18.0 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70078.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX70078.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70078.1 - 0.086 13.3 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70078.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70078.1 - 0.4 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Trypan_PARP PF05887.11 EAX70080.1 - 0.077 13.0 10.9 0.12 12.3 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX70081.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70081.1 - 0.13 11.3 0.1 0.13 11.3 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1493 PF07377.12 EAX70082.1 - 0.088 13.3 0.5 0.19 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2939 PF11159.8 EAX70084.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70084.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX70085.1 - 1.7e-43 148.6 0.8 1.9e-43 148.4 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70085.1 - 0.031 14.6 0.2 0.05 14.0 0.1 1.4 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Glyco_hydro_30 PF02055.16 EAX70087.1 - 5.4e-12 45.3 0.5 7.1e-12 45.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EAX70087.1 - 1.1e-07 32.0 2.1 2e-07 31.1 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Amidase02_C PF12123.8 EAX70088.1 - 0.0036 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF2897 PF11446.8 EAX70089.1 - 0.092 12.6 2.4 0.095 12.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70090.1 - 1.2e-63 213.3 5.6 1.3e-63 213.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX70090.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_D5 PF03288.16 EAX70091.1 - 1.6e-05 25.3 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70091.1 - 0.075 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX70092.1 - 5.4e-10 38.7 2.9 3e-09 36.3 2.5 2.1 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70092.1 - 0.13 12.3 0.0 0.91 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX70092.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 TMP PF05017.14 EAX70093.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1731 PF08338.11 EAX70095.1 - 0.23 11.3 0.1 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX70096.1 - 2.4e-23 82.8 4.1 3e-23 82.4 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70096.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Cystatin PF00031.21 EAX70097.1 - 0.013 15.7 0.1 0.015 15.6 0.1 1.0 1 0 0 1 1 1 0 Cystatin domain SpvB PF03534.13 EAX70097.1 - 0.047 12.9 0.5 0.044 13.0 0.5 1.0 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Tom5 PF10642.9 EAX70097.1 - 0.12 12.4 0.6 0.12 12.4 0.6 1.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF4795 PF16043.5 EAX70098.1 - 0.0077 15.9 2.2 0.019 14.6 2.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PTR PF12789.7 EAX70098.1 - 0.029 14.4 2.1 0.029 14.4 2.1 3.3 4 1 0 4 4 4 0 Phage tail repeat like YmaF PF12788.7 EAX70098.1 - 2.4 8.7 5.7 24 5.5 0.1 3.2 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX70098.1 - 3.2 8.2 16.2 3.7 8.0 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4108 PF13390.6 EAX70100.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX70102.1 - 0.018 15.4 0.4 0.025 15.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70102.1 - 0.95 8.4 2.2 1 8.3 2.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein FAS_N PF17828.1 EAX70103.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4106 PF13388.6 EAX70104.1 - 1.9e-217 722.5 24.0 2.2e-217 722.3 24.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.10 EAX70104.1 - 4.8 5.7 9.5 7.4 5.1 9.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup KilA-N PF04383.13 EAX70105.1 - 6.6e-36 122.6 0.3 6.6e-36 122.6 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70105.1 - 0.0092 16.6 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX70105.1 - 0.99 9.4 4.2 1.9 8.5 0.5 2.3 2 0 0 2 2 2 0 Tumour suppressor protein TPR_MLP1_2 PF07926.12 EAX70107.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX70107.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX70107.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX70108.1 - 1.6e-59 200.0 8.9 1.8e-59 199.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70109.1 - 0.00037 20.9 5.8 0.00062 20.2 3.5 2.5 2 1 0 2 2 2 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX70109.1 - 0.15 12.0 1.0 0.22 11.5 0.2 1.7 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain IstB_IS21 PF01695.17 EAX70110.1 - 2e-05 24.4 0.4 0.24 11.1 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70110.1 - 3.4e-05 24.2 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70110.1 - 5e-05 22.9 3.4 6.8e-05 22.4 2.0 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX70110.1 - 0.00036 20.6 5.1 0.00051 20.1 4.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70110.1 - 0.0005 19.9 0.1 0.00098 18.9 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX70110.1 - 0.0045 16.7 3.2 0.012 15.3 0.4 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX70110.1 - 0.006 16.4 1.1 0.006 16.4 1.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70110.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX70110.1 - 0.042 13.6 0.1 0.071 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX70110.1 - 0.066 12.8 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70110.1 - 0.076 13.4 0.1 0.74 10.2 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70110.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX70110.1 - 0.094 12.8 1.0 1.4 8.9 1.0 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX70110.1 - 0.28 11.5 4.9 3.9 7.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70110.1 - 3.8 8.2 12.2 0.16 12.6 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX70111.1 - 2.5e-128 426.6 6.8 2.8e-128 426.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) WASH_WAHD PF11945.8 EAX70113.1 - 0.0026 17.3 1.3 0.06 12.9 0.2 1.9 1 1 1 2 2 2 2 WAHD domain of WASH complex Muted PF14942.6 EAX70113.1 - 0.0039 17.5 0.8 0.55 10.6 0.0 2.0 2 0 0 2 2 2 2 Organelle biogenesis, Muted-like protein Mst1_SARAH PF11629.8 EAX70113.1 - 0.22 11.7 2.6 13 6.0 0.1 2.4 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Rsa3 PF14615.6 EAX70113.1 - 0.44 10.1 3.3 13 5.4 0.3 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF4106 PF13388.6 EAX70113.1 - 1.5 7.9 6.0 3.4 6.8 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4106) Pox_D5 PF03288.16 EAX70114.1 - 0.00016 22.1 4.0 0.0011 19.4 4.0 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Pox_D5 PF03288.16 EAX70115.1 - 0.00012 22.5 3.9 0.00091 19.7 3.9 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX70115.1 - 0.087 12.8 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF5365 PF17326.2 EAX70116.1 - 0.02 15.3 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PapD_N PF00345.20 EAX70117.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70117.1 - 0.031 14.3 0.5 0.042 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX70118.1 - 0.018 15.4 0.4 0.026 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70118.1 - 0.38 9.7 2.2 0.41 9.6 2.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX70118.1 - 2.6 8.0 4.9 2.8 7.9 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KIAA1430 PF13879.6 EAX70119.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue CompInhib_SCIN PF11546.8 EAX70120.1 - 0.054 13.5 0.9 0.061 13.4 0.9 1.1 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN HTH_32 PF13565.6 EAX70120.1 - 0.53 10.9 3.7 1.2 9.8 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain MULE PF10551.9 EAX70121.1 - 7.1e-11 42.4 1.5 1.3e-10 41.5 1.5 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX70121.1 - 0.0014 18.7 1.1 0.0049 16.9 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX70121.1 - 0.0095 14.8 0.2 0.015 14.2 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family T5orf172 PF10544.9 EAX70122.1 - 2.4e-06 28.0 0.2 4.9e-06 27.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX70124.1 - 8.1e-64 213.9 6.2 9e-64 213.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX70127.1 - 3.1e-72 238.5 46.9 9.6e-32 108.8 13.4 4.7 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX70127.1 - 0.03 14.1 0.9 0.058 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX70127.1 - 0.097 12.1 3.7 0.32 10.4 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PcfK PF14058.6 EAX70128.1 - 0.24 11.7 8.0 0.39 11.0 8.0 1.4 1 1 0 1 1 1 0 PcfK-like protein PSP PF04046.16 EAX70129.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MeaB PF03308.16 EAX70130.1 - 0.022 13.8 1.4 0.025 13.6 0.6 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX70130.1 - 0.061 13.1 3.0 0.087 12.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX70130.1 - 0.17 12.3 4.6 0.35 11.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) Transposase_24 PF03004.14 EAX70130.1 - 0.2 11.8 5.0 0.48 10.5 1.5 2.5 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF4108 PF13390.6 EAX70131.1 - 5.3e-64 214.5 5.9 5.9e-64 214.3 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70132.1 - 6.2e-05 23.4 2.2 0.00033 21.1 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70132.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Pox_D5 PF03288.16 EAX70133.1 - 9.7e-05 22.8 3.1 0.00056 20.3 3.1 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like GPS2_interact PF15784.5 EAX70134.1 - 0.019 15.4 0.4 0.023 15.1 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70134.1 - 0.12 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX70135.1 - 2.3e-71 239.2 3.7 3.1e-71 238.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX70137.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70138.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX70140.1 - 3.4e-98 327.9 8.3 4.2e-98 327.6 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX70140.1 - 0.16 12.9 0.7 5.2 8.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) KilA-N PF04383.13 EAX70142.1 - 6.2e-17 61.5 0.1 1.2e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain TMP PF05017.14 EAX70143.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX70144.1 - 6.1e-08 32.4 1.2 7.5e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70144.1 - 0.005 16.5 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70144.1 - 0.051 13.3 0.1 0.091 12.5 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70144.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF5446 PF17522.2 EAX70145.1 - 0.09 12.9 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4106 PF13388.6 EAX70146.1 - 3.1e-222 738.3 23.9 5.7e-222 737.4 23.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX70146.1 - 0.01 16.1 0.1 0.55 10.6 0.1 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated SPATA3 PF15662.5 EAX70146.1 - 8.6 6.9 16.7 19 5.8 16.7 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family PadR PF03551.14 EAX70147.1 - 0.11 12.5 0.0 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX70148.1 - 1.7e-25 88.8 20.9 8e-24 83.5 7.2 4.0 4 0 0 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX70148.1 - 0.012 15.2 8.8 0.26 10.9 8.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX70148.1 - 0.02 15.4 6.1 0.53 10.9 1.0 3.1 3 0 0 3 3 3 0 YmaF family Transposase_24 PF03004.14 EAX70148.1 - 0.11 12.6 5.0 0.56 10.3 4.8 2.2 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF3839 PF12943.7 EAX70149.1 - 7.8e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX70150.1 - 4e-72 241.7 4.1 5.1e-72 241.3 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ATP-synt_E PF05680.12 EAX70151.1 - 4.6 7.6 10.2 5.3 7.5 10.2 1.0 1 0 0 1 1 1 0 ATP synthase E chain DUF4108 PF13390.6 EAX70152.1 - 2.1e-61 206.0 8.3 2.4e-61 205.9 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70153.1 - 3.2e-05 24.3 3.4 0.00021 21.7 3.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PSP PF04046.16 EAX70154.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX70155.1 - 1.7e-44 150.2 1.2 2.5e-44 149.7 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70155.1 - 0.0046 17.6 0.1 0.013 16.1 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Mito_fiss_reg PF05308.11 EAX70156.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX70156.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4108 PF13390.6 EAX70157.1 - 9.8e-57 190.9 6.5 1.1e-56 190.7 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DDR PF08841.10 EAX70159.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX70159.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX70160.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 EAX70161.1 - 1.1e-67 229.1 1.6 1.5e-67 228.7 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Peptidase_C1 PF00112.23 EAX70162.1 - 2e-70 237.3 9.5 2.6e-70 236.9 9.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX70162.1 - 5.7e-09 36.3 0.1 9.2e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAX70162.1 - 2e-05 23.6 1.7 0.0047 15.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C14 PF00656.22 EAX70163.1 - 6.9e-18 65.5 2.8 7e-17 62.2 2.8 2.0 1 1 0 1 1 1 1 Caspase domain IL7 PF01415.16 EAX70163.1 - 0.046 13.8 1.6 0.074 13.1 0.7 1.8 2 0 0 2 2 2 0 Interleukin 7/9 family DUF3781 PF12636.7 EAX70164.1 - 0.021 14.7 1.0 0.033 14.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX70165.1 - 0.027 14.9 0.4 0.031 14.7 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70165.1 - 0.17 10.8 0.1 0.18 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX70168.1 - 1.4e-71 239.9 3.5 2.4e-71 239.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70168.1 - 0.1 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF1493 PF07377.12 EAX70169.1 - 0.072 13.6 1.3 0.096 13.2 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70169.1 - 0.16 12.1 2.8 5.9 7.0 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX70170.1 - 1.6e-31 108.1 14.6 1.6e-31 108.1 14.6 4.5 2 2 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX70170.1 - 0.038 13.7 1.1 0.077 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX70171.1 - 1.1e-06 28.3 1.9 1.1e-06 28.3 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX70171.1 - 4.2e-05 23.4 0.2 0.38 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70171.1 - 4.6e-05 23.7 0.1 0.00031 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX70171.1 - 7.6e-05 22.8 3.1 0.00016 21.7 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70171.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70171.1 - 0.0017 18.2 0.4 0.0036 17.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70171.1 - 0.0023 17.6 0.5 0.016 14.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70171.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX70171.1 - 0.054 13.0 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX70171.1 - 0.068 12.7 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX70171.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX70171.1 - 0.12 12.7 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX70171.1 - 0.21 11.9 4.3 4.1 7.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX70171.1 - 0.39 11.2 3.8 0.29 11.6 0.8 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3829 PF12889.7 EAX70171.1 - 1 8.8 8.6 0.4 10.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF3839 PF12943.7 EAX70172.1 - 1e-150 499.9 11.9 1.1e-150 499.7 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70172.1 - 0.048 13.5 0.4 0.16 11.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX70172.1 - 0.37 11.1 3.0 1 9.7 0.0 2.8 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX70172.1 - 0.65 10.5 6.1 1.5 9.3 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_22 PF13401.6 EAX70173.1 - 2.9e-05 24.4 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70173.1 - 3.8e-05 23.3 2.3 3.8e-05 23.3 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX70173.1 - 0.0001 22.1 0.2 0.31 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70173.1 - 0.0003 20.8 4.1 0.00045 20.2 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70173.1 - 0.00054 19.8 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70173.1 - 0.0011 18.8 0.5 0.0029 17.4 0.5 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70173.1 - 0.0031 17.2 2.5 0.0096 15.6 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70173.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX70173.1 - 0.062 12.9 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX70173.1 - 0.064 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX70173.1 - 0.078 13.4 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70173.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX70173.1 - 0.095 12.8 0.6 1.1 9.4 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX70173.1 - 8.1 7.2 10.7 0.5 11.1 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 FAS_N PF17828.1 EAX70174.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX70175.1 - 0.019 15.4 0.6 0.023 15.1 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70175.1 - 3.4 7.7 5.5 3.6 7.6 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX70176.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX70177.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70177.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX70179.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70179.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70179.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70179.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70179.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70179.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70179.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Chal_sti_synt_N PF00195.19 EAX70180.1 - 0.071 12.5 0.9 0.13 11.7 0.9 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Syja_N PF02383.18 EAX70180.1 - 0.087 12.1 0.5 0.094 12.0 0.5 1.0 1 0 0 1 1 1 0 SacI homology domain DUF3839 PF12943.7 EAX70182.1 - 4.7e-127 422.4 7.0 5.3e-127 422.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX70182.1 - 0.25 11.7 1.3 0.66 10.3 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4108 PF13390.6 EAX70183.1 - 1.3e-44 151.6 3.5 1.5e-44 151.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX70185.1 - 0.00026 21.5 0.2 0.0035 17.9 0.0 2.2 2 0 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX70185.1 - 0.0061 15.8 0.1 0.011 15.0 0.0 1.5 1 1 0 2 2 2 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX70185.1 - 0.031 13.8 0.7 0.2 11.2 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3148 PF11347.8 EAX70185.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) DUF4108 PF13390.6 EAX70186.1 - 3.9e-42 143.6 3.1 4.2e-42 143.4 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX70186.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX70188.1 - 3.3e-07 30.0 3.3 3.8e-07 29.8 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70188.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70188.1 - 0.00015 21.6 0.2 0.53 10.0 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70188.1 - 0.00036 20.6 4.0 0.00061 19.8 3.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70188.1 - 0.00071 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70188.1 - 0.0012 18.7 0.5 0.0035 17.2 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70188.1 - 0.0048 16.6 3.0 0.012 15.2 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70188.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX70188.1 - 0.082 12.5 0.0 0.26 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX70188.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX70188.1 - 0.11 13.0 0.1 0.87 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX70188.1 - 0.42 11.3 11.0 0.24 12.1 1.4 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 PTR PF12789.7 EAX70189.1 - 3.2e-09 36.7 1.5 3.2e-09 36.7 1.5 4.6 2 2 3 5 5 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX70189.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4116) Transposase_24 PF03004.14 EAX70189.1 - 6.7 6.8 12.1 3.7 7.7 1.2 3.0 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) DUF1493 PF07377.12 EAX70190.1 - 0.038 14.5 1.0 0.056 13.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70190.1 - 0.23 11.5 3.4 6.1 7.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF2939 PF11159.8 EAX70191.1 - 0.012 16.0 0.8 0.015 15.7 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70191.1 - 2 7.4 4.3 2.1 7.3 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX70191.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX70191.1 - 6.1 6.8 7.6 6.8 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX70192.1 - 0.012 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX70193.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70193.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX70194.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX70196.1 - 1.4e-60 203.4 9.3 1.5e-60 203.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX70196.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX70197.1 - 0.049 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX70197.1 - 1.8 8.5 3.8 3.4 7.6 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) FAS_N PF17828.1 EAX70199.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX70200.1 - 4.2e-28 97.4 0.5 9.9e-28 96.2 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70200.1 - 0.0036 17.9 0.3 0.013 16.1 0.0 2.1 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX70201.1 - 6.2e-05 22.6 3.6 8.7e-05 22.1 3.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX70201.1 - 0.0036 17.3 0.1 0.0088 16.1 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX70201.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Pox_A32 PF04665.12 EAX70202.1 - 6.1e-08 32.4 1.2 7.5e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70202.1 - 0.005 16.5 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70202.1 - 0.051 13.3 0.1 0.091 12.5 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70202.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX70203.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70203.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70203.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70203.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70203.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70203.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70203.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX70204.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3574 PF12098.8 EAX70205.1 - 0.048 13.5 1.3 0.056 13.2 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) T5orf172 PF10544.9 EAX70206.1 - 0.0002 21.9 0.8 0.00051 20.6 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX70206.1 - 0.0065 16.0 0.5 0.091 12.3 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX70206.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF3839 PF12943.7 EAX70207.1 - 3e-27 95.6 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX70207.1 - 0.14 12.7 1.1 0.88 10.1 0.2 2.0 1 1 0 2 2 2 0 Cell division protein ZapB APC_u14 PF16635.5 EAX70207.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DUF5105 PF17118.5 EAX70210.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) AbiJ_NTD4 PF18863.1 EAX70210.1 - 0.025 15.0 0.3 0.046 14.2 0.3 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 DUF4108 PF13390.6 EAX70211.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70212.1 - 3.2e-05 24.3 2.4 0.0002 21.8 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PTR PF12789.7 EAX70213.1 - 7.4e-66 218.1 46.3 9e-35 118.5 16.3 4.8 4 1 2 6 6 6 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX70213.1 - 0.14 12.0 0.8 0.22 11.4 0.8 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2785 PF10978.8 EAX70213.1 - 1.4 8.6 6.0 1.8 8.3 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2785) PH_TFIIH PF08567.11 EAX70213.1 - 2.3 8.6 6.4 40 4.6 0.1 4.6 2 1 4 6 6 6 0 TFIIH p62 subunit, N-terminal domain DUF4106 PF13388.6 EAX70214.1 - 5.2e-46 157.7 2.0 5.2e-46 157.7 2.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Noggin PF05806.12 EAX70215.1 - 0.29 11.0 1.0 0.44 10.4 1.0 1.2 1 0 0 1 1 1 0 Noggin DUF3408 PF11888.8 EAX70215.1 - 1.1 9.4 5.8 11 6.1 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MULE PF10551.9 EAX70216.1 - 2.7e-05 24.5 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Ank_2 PF12796.7 EAX70218.1 - 5.4e-131 427.5 63.2 3.4e-16 59.6 1.7 7.7 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX70218.1 - 4.7e-82 269.4 25.2 9.9e-12 45.1 0.2 10.4 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX70218.1 - 1.5e-74 237.0 19.7 3.6e-06 26.9 0.1 11.0 11 0 0 11 11 11 11 Ankyrin repeat Ank PF00023.30 EAX70218.1 - 4e-74 242.0 23.1 2.6e-07 30.8 0.3 11.0 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 EAX70218.1 - 1.4e-66 219.6 29.5 3.8e-10 39.8 0.1 7.5 2 1 8 10 10 10 10 Ankyrin repeats (many copies) DUF3677 PF12432.8 EAX70218.1 - 9.9e-07 29.0 0.1 86 3.6 0.0 8.2 1 1 9 10 10 10 0 Protein of unknown function (DUF3677) S4 PF01479.25 EAX70218.1 - 1.4e-06 27.9 0.8 79 3.1 0.0 8.1 10 0 0 10 10 10 0 S4 domain Glyco_hydro_20b PF02838.15 EAX70218.1 - 4.3e-05 24.3 9.3 7.7 7.3 0.1 6.1 1 1 4 5 5 5 1 Glycosyl hydrolase family 20, domain 2 DUF3718 PF12514.8 EAX70218.1 - 7.8e-05 22.8 18.4 2.9 8.1 0.1 9.1 5 5 6 11 11 11 1 Protein of unknown function (DUF3718) Arg_repressor PF01316.21 EAX70218.1 - 0.00012 21.8 7.0 1e+02 2.8 0.0 8.3 11 0 0 11 11 11 0 Arginine repressor, DNA binding domain Stap_Strp_toxin PF01123.20 EAX70218.1 - 0.0002 22.1 14.7 24 5.9 0.1 7.3 1 1 7 8 8 8 0 Staphylococcal/Streptococcal toxin, OB-fold domain Herpes_UL36 PF03586.13 EAX70218.1 - 0.00054 19.4 1.1 6.4 6.0 0.0 4.2 2 2 1 4 4 4 2 Herpesvirus UL36 tegument protein RGP PF03214.13 EAX70218.1 - 0.00064 19.0 0.0 48 2.9 0.0 5.5 1 1 5 8 8 8 0 Reversibly glycosylated polypeptide DUF1861 PF08950.10 EAX70218.1 - 0.0023 17.2 0.0 26 3.9 0.0 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1861) PrmC_N PF17827.1 EAX70218.1 - 0.0064 17.0 6.8 97 3.7 0.0 7.6 2 1 2 6 6 6 0 PrmC N-terminal domain DUF348 PF03990.14 EAX70218.1 - 0.022 14.5 8.4 2.6e+02 1.5 0.0 8.2 10 0 0 10 10 10 0 G5-linked-Ubiquitin-like domain DUF1103 PF06513.11 EAX70218.1 - 1 8.9 13.0 3.6 7.1 2.1 2.5 1 1 2 3 3 3 0 Repeat of unknown function (DUF1103) FAS_N PF17828.1 EAX70219.1 - 0.0024 17.9 0.2 0.0028 17.7 0.2 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX70220.1 - 2.8e-63 213.6 5.4 3.6e-63 213.3 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Mito_fiss_reg PF05308.11 EAX70221.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX70221.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PapD_N PF00345.20 EAX70223.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70223.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX70224.1 - 0.023 14.8 0.4 0.023 14.8 0.4 3.1 4 0 0 4 4 4 0 Phage tail repeat like DUF4108 PF13390.6 EAX70226.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX70227.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX70227.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DNA_pol_B_2 PF03175.13 EAX70228.1 - 3.3e-09 36.1 1.3 5.2e-09 35.5 1.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70228.1 - 0.089 12.8 0.0 0.71 9.9 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor FAS_N PF17828.1 EAX70229.1 - 0.013 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX70230.1 - 0.023 15.1 0.6 0.03 14.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70230.1 - 1 8.3 2.4 1 8.3 2.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX70230.1 - 1.4 8.9 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 T5orf172 PF10544.9 EAX70231.1 - 1.2e-06 28.9 0.2 3.1e-06 27.6 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70231.1 - 0.021 14.7 0.4 0.15 11.9 0.1 2.2 2 1 0 2 2 2 0 KilA-N domain Nckap1 PF09735.9 EAX70232.1 - 0.0067 14.5 2.7 0.0069 14.4 2.7 1.2 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Macoilin PF09726.9 EAX70232.1 - 0.87 8.1 11.8 1 7.8 11.8 1.0 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 EAX70232.1 - 2.1 6.4 9.7 2.6 6.1 9.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PH_11 PF15413.6 EAX70232.1 - 5.3 7.5 6.3 7.1 7.1 1.3 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain DUF5077 PF16871.5 EAX70232.1 - 6 6.7 12.3 1.5 8.7 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5077) DUF4108 PF13390.6 EAX70233.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX70234.1 - 6.1e-155 513.7 11.8 7.4e-155 513.5 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX70234.1 - 0.047 14.3 1.7 0.49 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX70234.1 - 0.36 11.3 3.7 9.9 6.7 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cytadhesin_P30 PF07271.11 EAX70235.1 - 1.8 8.0 18.6 2.3 7.7 18.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Coa1 PF08695.10 EAX70236.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 GPS2_interact PF15784.5 EAX70238.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70238.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX70239.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX70239.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX70240.1 - 3.4e-80 269.0 10.7 4.5e-80 268.6 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX70240.1 - 0.096 13.2 0.6 0.17 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CTD PF12815.7 EAX70241.1 - 0.0014 19.1 8.1 0.016 15.8 3.6 2.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Keratin_B2_2 PF13885.6 EAX70241.1 - 0.01 15.8 26.7 0.089 12.8 15.9 2.5 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein DUF1947 PF09183.10 EAX70241.1 - 0.83 10.0 12.1 2e+02 2.4 0.0 6.9 3 3 5 9 9 9 0 Domain of unknown function (DUF1947) DUF4108 PF13390.6 EAX70242.1 - 2e-57 193.1 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX70243.1 - 0.014 15.9 0.6 0.017 15.6 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70243.1 - 0.077 12.0 0.1 0.08 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain IstB_IS21 PF01695.17 EAX70244.1 - 2e-05 24.4 0.4 0.24 11.1 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX70244.1 - 3.1e-05 23.6 1.8 3.1e-05 23.6 1.8 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70244.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX70244.1 - 0.00027 21.0 4.5 0.00045 20.3 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70244.1 - 0.00053 19.8 0.1 0.00096 19.0 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70244.1 - 0.0022 17.8 1.2 0.0061 16.4 0.8 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70244.1 - 0.0041 16.8 2.3 0.009 15.7 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70244.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX70244.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX70244.1 - 0.085 12.3 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX70244.1 - 0.089 13.2 0.5 0.72 10.3 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX70244.1 - 0.73 10.1 6.6 4.6 7.5 0.3 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70244.1 - 4.3 8.1 10.7 0.36 11.5 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DNA_pol_B_2 PF03175.13 EAX70245.1 - 2.3e-22 79.5 3.6 2.9e-22 79.2 3.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70245.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX70246.1 - 6.1e-64 212.0 44.3 8e-32 109.1 14.5 5.1 2 2 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX70246.1 - 0.039 13.7 0.9 0.078 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX70246.1 - 0.22 10.9 4.2 0.51 9.8 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa GGDEF PF00990.21 EAX70247.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX70247.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX70247.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70248.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70249.1 - 0.096 12.6 1.7 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX70250.1 - 8.1e-17 61.5 3.3 1.3e-16 60.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX70250.1 - 0.038 14.3 0.3 0.11 12.8 0.1 1.9 1 1 1 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX70251.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70251.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70251.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70251.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Amidase02_C PF12123.8 EAX70252.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX70253.1 - 1.9e-158 525.2 13.7 2.3e-158 525.0 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70253.1 - 3.7 8.1 8.8 1.4 9.4 0.5 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KIAA1430 PF13879.6 EAX70255.1 - 0.0082 16.9 1.8 0.011 16.5 1.8 1.2 1 0 0 1 1 1 1 KIAA1430 homologue DUF4108 PF13390.6 EAX70256.1 - 7.7e-64 213.9 6.1 8.6e-64 213.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX70257.1 - 0.36 11.2 2.5 0.73 10.2 2.5 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MULE PF10551.9 EAX70258.1 - 6.1e-14 52.2 0.3 6.1e-14 52.2 0.3 2.4 3 0 0 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX70258.1 - 0.0034 17.1 0.3 0.016 15.0 0.2 1.9 1 1 1 2 2 2 1 Transposase Transposase_mut PF00872.18 EAX70258.1 - 0.047 12.5 2.5 0.16 10.8 2.5 1.8 1 1 0 1 1 1 0 Transposase, Mutator family DUF2960 PF11173.8 EAX70258.1 - 0.06 13.8 1.4 0.11 12.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) T5orf172 PF10544.9 EAX70260.1 - 0.00024 21.6 0.3 0.00056 20.4 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX70260.1 - 0.0092 15.5 1.0 0.1 12.1 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX70260.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX70261.1 - 4.1e-26 91.9 5.6 5.8e-26 91.4 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX70262.1 - 4.7e-155 514.1 13.2 5.8e-155 513.8 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70262.1 - 0.19 11.6 1.5 0.48 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX70262.1 - 0.37 11.3 6.5 2.1 8.9 0.7 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX70262.1 - 0.47 10.8 3.0 1.6 9.0 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain DUF2408 PF10303.9 EAX70262.1 - 1.6 9.3 5.7 0.83 10.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX70263.1 - 1.1e-69 234.6 6.5 1.4e-69 234.3 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX70263.1 - 0.065 13.4 0.1 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Associated with zinc fingers SDA1 PF05285.12 EAX70265.1 - 2.3 7.6 6.7 3.1 7.1 6.7 1.1 1 0 0 1 1 1 0 SDA1 DDE_1 PF03184.19 EAX70266.1 - 6.4e-10 39.0 0.0 7e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX70266.1 - 0.00054 19.7 0.0 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4107 PF13389.6 EAX70267.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70267.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX70268.1 - 1.8e-98 328.9 10.8 5.5e-98 327.2 10.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70268.1 - 0.0048 17.3 3.9 0.65 10.5 0.0 3.0 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase HAP1_N PF04849.13 EAX70268.1 - 0.014 14.7 0.4 0.019 14.2 0.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EAX70268.1 - 0.022 15.2 0.5 0.031 14.7 0.5 1.3 1 0 0 1 1 1 0 Fez1 Gly_rich PF12810.7 EAX70269.1 - 3.9e-47 161.2 43.2 5.8e-47 160.6 43.2 1.2 1 0 0 1 1 1 1 Glycine rich protein EF-hand_10 PF14788.6 EAX70270.1 - 0.0018 18.1 0.1 0.004 17.0 0.1 1.6 1 0 0 1 1 1 1 EF hand YABBY PF04690.13 EAX70270.1 - 0.0036 17.9 1.2 0.006 17.2 1.2 1.2 1 0 0 1 1 1 1 YABBY protein EVC2_like PF12297.8 EAX70270.1 - 0.0056 15.4 0.2 0.0056 15.4 0.2 1.4 2 0 0 2 2 2 1 Ellis van Creveld protein 2 like protein Pox_A32 PF04665.12 EAX70271.1 - 6e-07 29.2 2.6 6e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70271.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70271.1 - 7e-05 22.6 0.3 0.49 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70271.1 - 0.00011 22.2 2.8 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70271.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70271.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70271.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70271.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX70271.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX70271.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70271.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70271.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70271.1 - 0.3 11.3 4.1 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX70272.1 - 2.3e-41 140.1 1.0 4.5e-41 139.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX70272.1 - 0.0089 15.3 0.2 0.028 13.7 0.1 1.7 1 1 1 2 2 2 1 Acyl transferase RPAP3_C PF13877.6 EAX70272.1 - 0.08 13.5 1.8 1.5 9.4 0.3 2.4 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 FPN1 PF06963.12 EAX70272.1 - 0.27 9.7 0.1 0.42 9.1 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) GGDEF PF00990.21 EAX70275.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX70276.1 - 7.8e-63 210.7 6.0 8.7e-63 210.5 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX70277.1 - 8.5e-63 208.3 41.3 1.2e-31 108.5 13.9 4.7 2 2 3 5 5 4 3 Phage tail repeat like AviRa PF11599.8 EAX70277.1 - 0.092 12.2 3.5 0.29 10.6 0.7 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Peptidase_S66 PF02016.15 EAX70277.1 - 0.1 12.7 0.8 53 3.9 0.1 3.5 2 1 1 3 3 3 0 LD-carboxypeptidase N-terminal domain PH_TFIIH PF08567.11 EAX70277.1 - 0.23 11.8 6.1 26 5.3 0.2 4.3 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF4795 PF16043.5 EAX70277.1 - 0.82 9.2 10.8 2.1 7.9 9.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4404 PF14357.6 EAX70277.1 - 9.2 7.0 7.9 13 6.5 0.3 3.2 2 1 3 5 5 5 0 Domain of unknown function (DUF4404) DDE_1 PF03184.19 EAX70278.1 - 7.9e-13 48.4 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_B_2 PF03175.13 EAX70279.1 - 4.5e-09 35.7 0.1 9.7e-09 34.6 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70279.1 - 0.043 13.1 0.3 0.065 12.5 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Ins_beta PF03488.14 EAX70279.1 - 0.18 11.9 0.3 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DUF4107 PF13389.6 EAX70280.1 - 3.6e-44 150.8 1.0 4e-44 150.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70280.1 - 0.081 13.3 0.8 0.095 13.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX70281.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX70282.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70282.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70282.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70282.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70282.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70282.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX70283.1 - 3.3e-51 173.7 1.6 3.9e-51 173.4 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX70285.1 - 0.00014 21.8 3.5 0.00014 21.8 3.5 5.0 3 3 3 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX70285.1 - 0.024 14.4 0.1 0.15 11.8 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX70285.1 - 0.25 10.9 32.1 0.03 13.9 5.7 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) TP53IP5 PF15331.6 EAX70285.1 - 8.7 6.4 12.1 1 9.5 0.3 2.3 1 1 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Nucleopor_Nup85 PF07575.13 EAX70287.1 - 0.007 15.0 0.0 0.009 14.6 0.0 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF4108 PF13390.6 EAX70288.1 - 6.1e-60 201.3 7.5 6.7e-60 201.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70289.1 - 3.7e-05 24.1 2.3 0.00021 21.7 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Trypan_PARP PF05887.11 EAX70291.1 - 0.036 14.0 9.7 0.046 13.7 9.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PT-VENN PF04829.13 EAX70292.1 - 0.31 11.1 2.1 0.47 10.6 2.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 EAX70292.1 - 0.42 10.5 8.2 0.81 9.6 8.2 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain DUF4108 PF13390.6 EAX70294.1 - 3.3e-52 176.2 5.5 3.7e-52 176.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX70295.1 - 0.85 9.2 3.7 4.9 6.7 3.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ABC2_membrane_3 PF12698.7 EAX70296.1 - 4.8e-05 22.6 1.2 6.1e-05 22.3 1.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4366 PF14283.6 EAX70296.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 EAX70296.1 - 0.0039 17.1 1.3 0.0053 16.7 1.3 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAX70296.1 - 0.0041 16.6 0.2 0.0046 16.4 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) BatD PF13584.6 EAX70296.1 - 0.0087 14.9 0.1 0.0094 14.8 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance RIFIN PF02009.16 EAX70296.1 - 0.013 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX70296.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX70296.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OppC_N PF12911.7 EAX70296.1 - 0.026 14.5 0.9 0.051 13.5 0.9 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FeoB_associated PF12669.7 EAX70296.1 - 0.037 14.4 2.1 0.061 13.7 2.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CD34_antigen PF06365.12 EAX70296.1 - 0.04 13.5 0.2 0.056 13.0 0.2 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 EAX70296.1 - 0.098 12.7 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gemini_mov PF01708.16 EAX70296.1 - 1.7 8.4 4.1 3.5 7.5 1.5 2.0 1 1 1 2 2 2 0 Geminivirus putative movement protein DUF4108 PF13390.6 EAX70298.1 - 7.3e-42 142.7 3.5 8.1e-42 142.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX70298.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_D5 PF03288.16 EAX70299.1 - 5.5e-05 23.6 2.5 0.00024 21.5 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX70299.1 - 0.033 13.3 1.0 0.046 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX70300.1 - 6.6e-52 175.2 5.5 7.3e-52 175.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX70301.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX70301.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Rpn9_C PF18261.1 EAX70302.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Rpn9 C-terminal helix PTR PF12789.7 EAX70304.1 - 3e-09 36.8 1.3 3e-09 36.8 1.3 4.5 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX70304.1 - 0.052 13.1 8.4 0.033 13.8 5.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX70304.1 - 0.47 11.0 1.6 1.3 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Amidase02_C PF12123.8 EAX70306.1 - 0.0046 16.6 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX70306.1 - 0.15 12.0 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF1493 PF07377.12 EAX70308.1 - 0.025 15.0 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70308.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein KilA-N PF04383.13 EAX70309.1 - 4.1e-41 139.3 0.3 9.2e-41 138.2 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70309.1 - 0.011 16.4 0.1 0.022 15.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX70310.1 - 4.3e-10 39.0 3.2 2.3e-09 36.6 3.2 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70310.1 - 0.13 12.3 0.0 0.93 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX70310.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 IstB_IS21 PF01695.17 EAX70311.1 - 0.0094 15.7 0.2 0.034 13.9 0.1 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein Frtz PF11768.8 EAX70311.1 - 0.039 12.3 0.0 0.041 12.2 0.0 1.0 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RNA_helicase PF00910.22 EAX70311.1 - 0.04 14.3 0.1 0.043 14.2 0.1 1.1 1 0 0 1 1 1 0 RNA helicase Rad10 PF03834.14 EAX70311.1 - 0.079 13.0 0.1 0.11 12.5 0.1 1.3 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) MULE PF10551.9 EAX70313.1 - 6.7e-11 42.5 0.1 1.2e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX70313.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 PWI domain KilA-N PF04383.13 EAX70314.1 - 7.8e-46 154.5 0.1 1.3e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX70314.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Meiosis_expr PF15163.6 EAX70315.1 - 0.11 13.2 1.5 0.14 12.8 0.6 1.6 2 0 0 2 2 2 0 Meiosis-expressed PSP PF04046.16 EAX70316.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70317.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX70318.1 - 5.7e-35 120.9 3.4 6.9e-35 120.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX70318.1 - 0.028 12.9 0.9 0.027 12.9 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase P22_AR_C PF10548.9 EAX70320.1 - 0.082 13.1 0.1 20 5.5 0.0 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain PBD PF00786.28 EAX70321.1 - 6e-18 65.0 0.6 2e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 P21-Rho-binding domain Tudor_RapA PF18337.1 EAX70321.1 - 0.085 13.0 0.2 9.5 6.5 0.1 2.6 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain DUF257 PF03192.13 EAX70322.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX70322.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2960 PF11173.8 EAX70323.1 - 0.021 15.3 0.3 0.058 13.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Pox_A32 PF04665.12 EAX70324.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70324.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70324.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70324.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4107 PF13389.6 EAX70325.1 - 2.8e-71 238.9 3.6 3.8e-71 238.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX70326.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70326.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70326.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70326.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70326.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70326.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70326.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70326.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX70326.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70326.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70326.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70326.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX70327.1 - 0.0037 16.9 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX70328.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70329.1 - 0.069 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP AAA_22 PF13401.6 EAX70330.1 - 2.1e-05 24.8 0.3 0.00016 22.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70330.1 - 2.1e-05 24.3 0.3 0.24 11.1 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70330.1 - 0.00012 22.2 3.4 0.00024 21.2 3.4 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70330.1 - 0.00043 20.1 0.1 0.00076 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX70330.1 - 0.00044 19.8 2.3 0.00044 19.8 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX70330.1 - 0.0012 18.7 0.7 0.0033 17.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70330.1 - 0.002 17.8 0.5 0.015 14.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70330.1 - 0.011 16.0 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX70330.1 - 0.046 13.3 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70330.1 - 0.059 13.8 0.1 0.52 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX70330.1 - 0.06 12.9 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX70330.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX70330.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX70330.1 - 0.37 11.1 4.7 8.1 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX70330.1 - 5 7.3 12.8 4.7 7.4 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF4106 PF13388.6 EAX70331.1 - 4.9e-212 704.6 19.2 5.9e-212 704.4 19.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX70331.1 - 0.00095 19.4 0.1 0.016 15.5 0.2 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX70331.1 - 0.11 13.1 0.7 0.28 11.8 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit DIT1_PvcA PF05141.12 EAX70331.1 - 0.35 10.3 8.7 0.58 9.6 8.7 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein WBS_methylT PF12589.8 EAX70331.1 - 2.2 9.1 6.7 19 6.1 1.4 2.8 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome TMP PF05017.14 EAX70333.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70334.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2939 PF11159.8 EAX70335.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70335.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX70336.1 - 2e-34 117.8 0.2 2e-34 117.8 0.2 1.8 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX70336.1 - 0.0033 17.6 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX70336.1 - 0.41 11.1 6.2 2.8 8.4 1.8 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 KilA-N PF04383.13 EAX70337.1 - 1.1e-24 86.4 0.1 1.2e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX70338.1 - 0.0069 16.4 11.5 0.024 14.7 1.8 3.2 4 1 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX70338.1 - 0.0074 15.9 1.9 0.017 14.8 1.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) eIF-3_zeta PF05091.12 EAX70340.1 - 7.7 5.4 23.7 8.5 5.2 23.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3839 PF12943.7 EAX70342.1 - 1.9e-155 515.4 13.5 2.2e-155 515.2 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70342.1 - 1.1 9.7 5.3 4.7 7.7 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_D5 PF03288.16 EAX70343.1 - 2.3e-05 24.8 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX70343.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX70343.1 - 0.057 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX70345.1 - 1.1e-57 194.0 4.1 1.2e-57 193.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX70346.1 - 2.7e-19 69.1 0.2 3.6e-19 68.6 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain Cytadhesin_P30 PF07271.11 EAX70347.1 - 7.5 6.0 17.7 9.2 5.7 17.7 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Amidase02_C PF12123.8 EAX70348.1 - 0.0022 17.7 0.0 0.0064 16.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX70348.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Apolipoprotein PF01442.18 EAX70349.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pox_A32 PF04665.12 EAX70350.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70350.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70350.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70350.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX70351.1 - 6e-08 32.4 1.4 1e-07 31.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX70353.1 - 4.8e-22 78.5 5.0 5.7e-22 78.2 5.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX70355.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain T5orf172 PF10544.9 EAX70357.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX70358.1 - 2.3e-150 498.8 13.9 2.6e-150 498.6 13.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70358.1 - 0.037 13.9 1.2 0.1 12.5 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX70358.1 - 0.27 11.7 5.7 1.6 9.2 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX70359.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70359.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70359.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70359.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70359.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70359.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70359.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX70360.1 - 6.3e-35 119.4 0.1 1.1e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX70361.1 - 5.6e-07 30.0 0.2 1.1e-06 29.1 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Csm1_N PF18504.1 EAX70362.1 - 0.00011 22.5 4.4 0.0088 16.4 0.0 2.3 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX70362.1 - 0.00027 21.0 8.8 0.0013 18.7 8.9 1.8 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain HMMR_N PF15905.5 EAX70362.1 - 0.0012 18.4 4.1 0.0013 18.3 4.1 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 EAX70362.1 - 0.0017 18.7 3.7 0.0026 18.1 3.7 1.3 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX70362.1 - 0.0024 16.8 4.6 0.0027 16.7 4.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 EAX70362.1 - 0.0027 18.0 4.4 0.0029 17.9 4.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF641 PF04859.12 EAX70362.1 - 0.0039 17.5 4.0 0.0054 17.1 4.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 EAX70362.1 - 0.0057 16.5 1.5 0.0057 16.5 1.5 2.9 2 1 2 4 4 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 EAX70362.1 - 0.0088 15.9 2.8 0.012 15.5 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) HemX PF04375.14 EAX70362.1 - 0.012 15.0 4.1 0.014 14.7 4.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 EAX70362.1 - 0.012 15.8 5.7 0.015 15.4 5.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EAX70362.1 - 0.015 15.4 7.4 0.018 15.1 6.7 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GNT-I PF03071.15 EAX70362.1 - 0.026 13.3 0.9 0.033 13.0 0.9 1.1 1 0 0 1 1 1 0 GNT-I family FAM76 PF16046.5 EAX70362.1 - 0.035 13.5 4.6 0.042 13.2 4.6 1.1 1 0 0 1 1 1 0 FAM76 protein Phage_GP20 PF06810.11 EAX70362.1 - 0.049 13.4 7.5 0.87 9.4 4.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.9 EAX70362.1 - 0.05 12.7 5.3 0.053 12.6 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EAX70362.1 - 0.084 12.9 1.3 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EAX70362.1 - 0.088 12.0 3.7 0.1 11.8 3.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 EAX70362.1 - 0.12 12.5 9.3 0.24 11.5 8.5 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EAX70362.1 - 0.25 11.5 6.7 21 5.3 0.0 2.5 1 1 0 2 2 2 0 bZIP transcription factor Exonuc_VII_L PF02601.15 EAX70362.1 - 0.27 10.8 3.3 0.28 10.7 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3847 PF12958.7 EAX70362.1 - 0.3 11.2 6.1 9.1 6.5 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF16 PF01519.16 EAX70362.1 - 0.44 11.1 6.6 1.1 9.7 6.6 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 EAX70362.1 - 0.5 10.5 7.7 0.72 10.0 6.5 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 COMP PF11598.8 EAX70362.1 - 0.54 10.8 5.9 1.8 9.1 3.2 2.3 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 EAX70362.1 - 1.4 8.7 8.8 1.4 8.7 3.8 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1493 PF07377.12 EAX70363.1 - 0.019 15.4 0.9 0.037 14.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Mito_fiss_reg PF05308.11 EAX70364.1 - 0.086 12.9 0.6 0.092 12.8 0.6 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4108 PF13390.6 EAX70366.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX70366.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX70367.1 - 9.4e-06 26.0 2.6 5.3e-05 23.6 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70367.1 - 0.057 14.0 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70367.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2939 PF11159.8 EAX70368.1 - 0.015 15.7 0.5 0.017 15.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70368.1 - 2 7.3 3.3 2 7.4 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX70368.1 - 3.6 7.6 7.2 3.8 7.5 7.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX70371.1 - 0.089 13.3 0.6 0.19 12.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF5446 PF17522.2 EAX70372.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4108 PF13390.6 EAX70373.1 - 1.9e-55 186.7 5.5 2.1e-55 186.6 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70374.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Nab1 PF04902.12 EAX70375.1 - 0.03 14.7 1.0 0.034 14.6 1.0 1.0 1 0 0 1 1 1 0 Conserved region in Nab1 DUF4107 PF13389.6 EAX70376.1 - 0.065 13.4 0.3 0.1 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX70377.1 - 7.6e-09 35.4 0.0 8.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70377.1 - 0.00025 20.7 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF2939 PF11159.8 EAX70378.1 - 0.012 16.0 0.8 0.015 15.7 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70378.1 - 2 7.4 4.3 2.1 7.3 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX70378.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX70378.1 - 6.1 6.8 7.6 6.8 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX70379.1 - 0.018 15.1 0.2 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX70381.1 - 2.7e-07 30.3 0.1 4.9e-07 29.5 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein Pox_A32 PF04665.12 EAX70382.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX70382.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase PSP PF04046.16 EAX70383.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70384.1 - 0.041 14.4 3.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX70385.1 - 5.5e-94 308.9 2.0 1.6e-18 67.0 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX70385.1 - 4.1e-66 218.5 0.5 3.3e-12 46.7 0.0 6.5 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX70385.1 - 4e-58 192.7 2.9 5.7e-10 39.3 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX70385.1 - 6.9e-58 190.7 0.0 5.2e-07 29.8 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX70385.1 - 2.7e-48 156.3 0.0 8.2e-06 25.8 0.0 8.2 9 0 0 9 9 9 7 Ankyrin repeat ENTH PF01417.20 EAX70385.1 - 9.6e-06 25.7 1.7 53 3.9 0.0 6.6 3 1 5 8 8 8 0 ENTH domain PilZ_2 PF16823.5 EAX70385.1 - 6.6e-05 23.1 0.0 0.5 10.5 0.0 3.2 1 1 3 4 4 4 2 Atypical PilZ domain, cyclic di-GMP receptor DUF1897 PF09005.10 EAX70385.1 - 0.0005 19.5 0.2 1.3e+02 2.2 0.0 6.7 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) Pox_E8 PF03394.13 EAX70385.1 - 0.0038 16.8 4.9 21 4.6 0.1 5.7 3 2 2 6 6 6 0 Poxvirus E8 protein DUF2795 PF11387.8 EAX70385.1 - 0.004 17.3 4.7 1.8e+02 2.4 0.0 6.6 8 0 0 8 8 8 0 Protein of unknown function (DUF2795) DUF2689 PF10894.8 EAX70385.1 - 0.0046 16.7 0.0 43 4.0 0.0 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2689) PUB_1 PF18486.1 EAX70385.1 - 0.14 12.1 0.0 62 3.6 0.0 3.1 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain DNA_pol_B_2 PF03175.13 EAX70386.1 - 1.3e-23 83.6 10.2 6.6e-23 81.3 10.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70386.1 - 0.028 14.4 0.0 0.92 9.5 0.0 3.0 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX70386.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Amidase02_C PF12123.8 EAX70387.1 - 0.0044 16.7 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DASH_Dad2 PF08654.10 EAX70388.1 - 2.2e-08 34.4 47.8 0.02 15.3 1.2 6.6 5 1 1 6 6 6 6 DASH complex subunit Dad2 DUF5638 PF18688.1 EAX70388.1 - 7.1e-07 29.5 51.8 0.31 11.4 2.9 6.0 1 1 5 6 6 6 6 Family of unknown function (DUF5638) Laminin_II PF06009.12 EAX70388.1 - 0.00019 21.5 71.3 0.032 14.3 10.6 4.8 1 1 4 5 5 5 5 Laminin Domain II LppA PF16708.5 EAX70388.1 - 0.00067 19.6 24.4 9 6.2 0.3 6.0 4 2 1 6 6 6 0 Lipoprotein confined to pathogenic Mycobacterium Fzo_mitofusin PF04799.13 EAX70388.1 - 0.0067 16.0 57.1 1.9 8.1 2.9 6.1 1 1 5 6 6 6 5 fzo-like conserved region DUF3135 PF11333.8 EAX70388.1 - 0.012 15.8 10.8 2.7 8.3 0.3 4.8 3 2 2 5 5 5 0 Protein of unknown function (DUF3135) Myosin_tail_1 PF01576.19 EAX70388.1 - 0.03 12.2 82.7 0.011 13.5 58.7 2.2 1 1 1 2 2 2 0 Myosin tail DMPK_coil PF08826.10 EAX70388.1 - 0.055 13.6 92.0 0.36 11.0 3.8 10.1 2 1 9 11 11 11 0 DMPK coiled coil domain like DUF812 PF05667.11 EAX70388.1 - 0.077 11.9 87.0 0.072 12.0 10.8 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EAX70388.1 - 0.31 11.1 86.2 0.54 10.3 19.5 4.7 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EAX70388.1 - 0.59 9.4 66.2 0.41 9.9 4.2 5.4 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) MoCF_biosynth PF00994.24 EAX70388.1 - 0.78 9.4 18.2 21 4.8 0.2 5.7 1 1 5 6 6 6 0 Probable molybdopterin binding domain BST2 PF16716.5 EAX70388.1 - 0.88 10.2 81.1 1.9 9.1 5.5 6.8 4 2 1 6 6 6 0 Bone marrow stromal antigen 2 Prefoldin_2 PF01920.20 EAX70388.1 - 0.95 9.4 81.7 3.7 7.6 5.4 6.8 5 1 3 8 8 8 0 Prefoldin subunit DUF4686 PF15742.5 EAX70388.1 - 1.9 7.5 81.1 2.4 7.2 39.8 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4686) Filament PF00038.21 EAX70388.1 - 2.3 7.7 71.2 0.64 9.6 15.8 3.4 1 1 3 4 4 4 0 Intermediate filament protein FlaC_arch PF05377.11 EAX70388.1 - 3 8.3 82.0 0.89 10.0 4.9 8.0 1 1 10 11 11 10 0 Flagella accessory protein C (FlaC) Angiomotin_C PF12240.8 EAX70388.1 - 4.3 6.8 55.8 3.9 7.0 2.6 6.3 1 1 5 6 6 6 0 Angiomotin C terminal Tropomyosin PF00261.20 EAX70388.1 - 6.3 6.1 80.2 59 2.9 58.6 2.7 1 1 1 2 2 2 0 Tropomyosin APG6_N PF17675.1 EAX70388.1 - 7 7.2 92.9 7.3 7.1 21.0 4.9 1 1 4 5 5 5 0 Apg6 coiled-coil region Med9 PF07544.13 EAX70388.1 - 8 6.6 70.8 4 7.6 5.7 6.1 1 1 5 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 PTR PF12789.7 EAX70389.1 - 1.5e-12 47.4 17.8 3e-08 33.6 0.8 4.6 4 1 1 5 5 5 2 Phage tail repeat like DUF3417 PF11897.8 EAX70389.1 - 0.007 16.8 2.6 0.12 12.9 0.3 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX70389.1 - 0.099 12.4 3.0 1.9 8.2 0.5 2.8 2 1 1 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 NPV_P10 PF05531.12 EAX70389.1 - 0.56 10.7 9.1 9.3 6.8 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 EAX70389.1 - 6.8 6.0 9.5 14 5.0 9.5 1.4 1 0 0 1 1 1 0 FAM76 protein DUF1731 PF08338.11 EAX70390.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX70391.1 - 1.6e-63 212.9 5.9 1.8e-63 212.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70392.1 - 1.1 9.2 3.4 1.8 8.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX70393.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX70394.1 - 0.039 13.8 0.6 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70395.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PapD_N PF00345.20 EAX70397.1 - 0.025 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4106 PF13388.6 EAX70398.1 - 3.3e-227 754.6 15.9 3.7e-227 754.4 15.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) TFIIA PF03153.13 EAX70398.1 - 0.25 11.3 14.1 0.31 11.0 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T5orf172 PF10544.9 EAX70399.1 - 0.00011 22.7 0.2 0.00025 21.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX70399.1 - 0.0069 16.0 0.4 0.099 12.2 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX70399.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX70399.1 - 0.036 13.9 0.5 0.13 12.1 0.2 2.2 2 1 0 2 2 2 0 KilA-N domain vATP-synt_E PF01991.18 EAX70400.1 - 2.3e-19 69.6 12.0 3e-19 69.2 12.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2777 PF10949.8 EAX70400.1 - 0.00059 19.6 2.0 0.00078 19.2 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2777) DUF3145 PF11343.8 EAX70400.1 - 0.018 14.6 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) HemN_C PF06969.16 EAX70400.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 HemN C-terminal domain DDE_Tnp_4 PF13359.6 EAX70400.1 - 0.17 11.5 1.1 0.21 11.3 1.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Mem_trans PF03547.18 EAX70400.1 - 0.21 9.9 0.6 0.23 9.8 0.6 1.1 1 0 0 1 1 1 0 Membrane transport protein SMC_N PF02463.19 EAX70400.1 - 0.22 10.9 0.9 0.26 10.7 0.9 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PdxJ PF03740.13 EAX70400.1 - 0.29 10.2 5.8 0.64 9.1 3.3 2.0 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ DUF5320 PF17253.2 EAX70400.1 - 0.56 11.3 5.2 1.1 10.4 5.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Pox_A32 PF04665.12 EAX70403.1 - 4.9e-07 29.5 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein TMP PF05017.14 EAX70404.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3781 PF12636.7 EAX70405.1 - 0.027 14.3 1.0 0.047 13.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX70406.1 - 0.036 14.5 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PapD_N PF00345.20 EAX70407.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70407.1 - 0.078 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX70407.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) HTH_32 PF13565.6 EAX70408.1 - 2.6 8.7 6.7 4.9 7.9 6.7 1.5 1 1 0 1 1 1 0 Homeodomain-like domain DNA_pol_B_2 PF03175.13 EAX70409.1 - 7.7e-25 87.7 8.5 3.2e-24 85.6 8.5 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70409.1 - 0.033 14.2 0.1 0.79 9.7 0.0 3.0 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor Phage_fiber PF03335.13 EAX70410.1 - 0.17 12.1 4.8 1.8 8.9 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX70410.1 - 0.29 11.7 1.8 7.6 7.1 0.1 2.1 1 1 0 2 2 2 0 YmaF family Pox_A32 PF04665.12 EAX70413.1 - 3.9e-07 29.8 0.0 5.2e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX70416.1 - 4.3e-07 29.6 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX70417.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX70418.1 - 6.4e-08 32.4 3.5 6.4e-08 32.4 3.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70418.1 - 3.1e-05 24.3 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70418.1 - 4.3e-05 23.3 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70418.1 - 0.00016 21.7 3.5 0.00036 20.6 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70418.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX70418.1 - 0.0018 17.9 0.6 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX70418.1 - 0.0031 17.3 1.6 0.0083 15.9 1.6 1.8 1 1 0 1 1 1 1 AAA domain Epimerase_2 PF02350.19 EAX70418.1 - 0.0063 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase AAA_19 PF13245.6 EAX70418.1 - 0.0095 16.3 0.0 0.023 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX70418.1 - 0.069 12.7 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX70418.1 - 0.077 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX70418.1 - 0.087 13.2 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70418.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70418.1 - 0.52 10.6 4.5 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX70420.1 - 7.5e-19 68.1 1.6 1.3e-18 67.4 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX70420.1 - 3.2e-06 27.6 0.2 1.4e-05 25.6 0.1 2.1 2 1 0 2 2 2 1 T5orf172 domain RUN PF02759.19 EAX70420.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 RUN domain CotJB PF12652.7 EAX70420.1 - 0.57 10.4 2.5 13 6.1 0.4 2.8 2 1 1 3 3 3 0 CotJB protein HNH_3 PF13392.6 EAX70423.1 - 3.4e-07 29.9 0.3 3.4e-07 29.9 0.3 1.8 2 0 0 2 2 2 1 HNH endonuclease Radial_spoke PF04712.12 EAX70423.1 - 0.036 13.0 6.3 0.037 13.0 6.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF740 PF05340.12 EAX70423.1 - 2.7 6.7 5.2 3 6.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Pox_A32 PF04665.12 EAX70424.1 - 4.7e-07 29.5 3.2 8.5e-07 28.7 3.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX70424.1 - 0.00091 19.0 0.1 0.38 10.5 0.0 2.5 2 2 0 2 2 2 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70424.1 - 0.0047 16.9 4.1 0.0099 15.9 3.8 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX70424.1 - 0.0089 15.7 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EAX70424.1 - 0.011 16.0 0.1 0.054 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX70424.1 - 0.011 15.9 4.8 2.6 8.4 0.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DEAD PF00270.29 EAX70424.1 - 0.077 12.8 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70424.1 - 0.1 12.4 0.8 0.18 11.6 0.8 1.7 1 1 0 1 1 1 0 AAA domain DUF1493 PF07377.12 EAX70427.1 - 0.031 14.7 1.2 0.044 14.3 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70427.1 - 0.31 11.1 4.0 7.3 6.7 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PSP PF04046.16 EAX70429.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70430.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX70431.1 - 9e-10 38.5 10.4 4.3e-09 36.3 1.5 4.2 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX70431.1 - 0.0023 17.5 14.2 0.041 13.5 2.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX70431.1 - 0.063 13.8 3.1 18 6.0 0.1 3.4 4 0 0 4 4 4 0 YmaF family DUF4108 PF13390.6 EAX70432.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70433.1 - 1.6 8.7 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) FliD_N PF02465.18 EAX70435.1 - 0.31 11.8 4.8 0.52 11.0 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX70435.1 - 2 7.1 3.9 2.6 6.7 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TMP PF05017.14 EAX70436.1 - 0.12 13.0 7.9 6.3 7.9 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX70436.1 - 5.3 7.0 8.4 5.6 6.9 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4116 PF13475.6 EAX70438.1 - 0.022 14.5 0.4 0.073 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX70439.1 - 0.018 15.5 2.0 0.022 15.2 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX70440.1 - 4.3e-06 26.4 1.8 4.3e-06 26.4 1.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX70440.1 - 7.4e-05 23.1 0.2 0.00046 20.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX70440.1 - 0.00019 21.5 3.5 0.00047 20.2 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX70440.1 - 0.00019 21.2 0.2 0.79 9.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX70440.1 - 0.00064 19.5 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70440.1 - 0.0016 18.3 0.6 0.0031 17.4 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70440.1 - 0.0022 17.7 0.5 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX70440.1 - 0.0081 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase AAA_19 PF13245.6 EAX70440.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX70440.1 - 0.063 12.8 0.1 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX70440.1 - 0.077 12.6 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70440.1 - 0.09 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70440.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70440.1 - 0.4 11.0 3.6 14 6.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX70441.1 - 6.4e-23 81.4 10.7 2.1e-22 79.6 10.7 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX70442.1 - 7.9e-06 25.8 1.1 7.9e-06 25.8 1.1 4.5 6 0 0 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX70442.1 - 0.044 13.5 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX70442.1 - 1.2 8.8 16.0 0.99 9.0 6.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) T5orf172 PF10544.9 EAX70443.1 - 7.7e-07 29.6 0.2 1.6e-06 28.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX70444.1 - 0.019 15.4 0.7 0.038 14.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PapD_N PF00345.20 EAX70446.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX70447.1 - 3.6e-64 215.0 7.0 4e-64 214.9 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX70447.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Btz PF09405.10 EAX70448.1 - 0.086 13.1 4.1 0.11 12.7 4.1 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding GGDEF PF00990.21 EAX70448.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3839 PF12943.7 EAX70450.1 - 3.7e-79 265.6 9.6 4.9e-79 265.2 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70450.1 - 0.075 12.9 1.2 0.3 10.9 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF1493 PF07377.12 EAX70451.1 - 0.033 14.7 0.9 0.067 13.7 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PapD_N PF00345.20 EAX70452.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70452.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX70453.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70453.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX70455.1 - 1.8e-20 73.3 4.4 3.2e-20 72.4 4.4 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70455.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein KilA-N PF04383.13 EAX70456.1 - 2e-41 140.3 0.4 5.3e-41 139.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX70456.1 - 0.32 11.0 2.3 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DDE_1 PF03184.19 EAX70457.1 - 1.6e-10 40.9 0.0 2.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX70457.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3839 PF12943.7 EAX70458.1 - 2.6e-40 138.4 5.1 3.8e-40 137.9 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX70458.1 - 0.32 11.1 4.6 3 8.0 2.2 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Pox_A32 PF04665.12 EAX70459.1 - 7.8e-08 32.1 0.5 8.6e-08 31.9 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70459.1 - 0.0076 15.9 0.1 0.008 15.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX70459.1 - 0.056 13.4 0.4 0.52 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX70459.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein IstB_IS21 PF01695.17 EAX70460.1 - 1.9e-05 24.5 0.4 0.21 11.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70460.1 - 3.1e-05 24.3 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70460.1 - 5.2e-05 22.8 1.8 5.2e-05 22.8 1.8 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX70460.1 - 0.00053 19.8 0.1 0.001 18.9 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX70460.1 - 0.00053 20.0 5.7 0.00067 19.7 4.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX70460.1 - 0.005 16.5 2.9 0.014 15.1 0.2 2.5 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX70460.1 - 0.0067 16.2 1.1 0.0067 16.2 1.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX70460.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX70460.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70460.1 - 0.076 13.4 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70460.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX70460.1 - 0.092 12.8 1.2 1.4 9.0 1.2 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX70460.1 - 0.29 11.4 5.1 3.9 7.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70460.1 - 4.8 7.9 12.9 0.31 11.7 3.6 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 RHH_3 PF12651.7 EAX70461.1 - 0.01 15.8 0.2 0.018 15.0 0.0 1.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Tho1_MOS11_C PF18592.1 EAX70461.1 - 0.094 12.5 0.0 3.3 7.6 0.0 2.7 2 1 1 3 3 3 0 Tho1/MOS11 C-terminal domain DUF4107 PF13389.6 EAX70463.1 - 1.7e-26 93.3 0.2 1.9e-26 93.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) zinc_ribbon_5 PF13719.6 EAX70463.1 - 0.48 10.2 1.3 1.2 9.0 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Nab1 PF04902.12 EAX70464.1 - 0.015 15.7 1.6 0.018 15.5 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 T5orf172 PF10544.9 EAX70465.1 - 4.9e-07 30.2 0.3 9.6e-07 29.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX70465.1 - 0.082 13.6 0.4 0.22 12.2 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX70466.1 - 1.2e-30 105.6 0.8 2.3e-30 104.7 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX70467.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70467.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70467.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70467.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70467.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70467.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70467.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX70470.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70470.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX70471.1 - 1.4e-10 40.7 2.3 6.8e-10 38.4 2.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70471.1 - 0.12 12.4 0.0 0.91 9.6 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4107 PF13389.6 EAX70473.1 - 3.9e-64 215.7 12.3 2e-62 210.2 12.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70473.1 - 0.1 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX70474.1 - 1.2e-60 203.6 9.7 1.3e-60 203.5 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly_rich PF12810.7 EAX70476.1 - 1.7e-47 162.4 38.5 2.1e-47 162.1 38.5 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX70477.1 - 3.3e-102 341.1 8.2 3.8e-102 340.9 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX70477.1 - 0.21 11.9 1.3 0.44 10.9 1.3 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit PapD_N PF00345.20 EAX70479.1 - 0.054 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX70480.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70480.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4106 PF13388.6 EAX70481.1 - 4e-188 625.9 19.3 4e-188 625.9 19.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX70482.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX70486.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70487.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX70488.1 - 1e-24 87.3 6.6 1.7e-24 86.5 6.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70488.1 - 0.089 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Pox_D5 PF03288.16 EAX70489.1 - 6.6e-05 23.3 3.1 0.00035 21.0 3.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70489.1 - 0.0062 17.1 0.3 0.013 16.1 0.3 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70489.1 - 0.094 12.7 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX70490.1 - 6.8e-61 204.4 8.1 7.6e-61 204.2 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX70491.1 - 3e-06 27.7 0.3 8e-06 26.3 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70491.1 - 0.016 15.1 2.1 0.069 13.0 0.9 2.5 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX70491.1 - 0.047 13.2 0.9 3.4 7.1 0.3 2.1 2 0 0 2 2 2 0 Legume lectin domain FRG PF08867.11 EAX70491.1 - 0.05 14.6 0.1 1.2 10.2 0.0 2.2 2 0 0 2 2 2 0 FRG domain DNA_pol_B_2 PF03175.13 EAX70493.1 - 2.9e-20 72.6 4.3 3.6e-20 72.3 4.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70493.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PapD_N PF00345.20 EAX70494.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2897 PF11446.8 EAX70495.1 - 1.1 9.2 3.8 2.4 8.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX70496.1 - 5.6e-25 87.4 0.3 1.4e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX70497.1 - 1.4e-71 239.9 3.6 1.8e-71 239.5 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX70500.1 - 4.1e-41 139.3 0.2 4.1e-41 139.3 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX70500.1 - 0.084 12.1 0.2 0.4 9.9 0.1 1.9 1 1 1 2 2 2 0 Acyl transferase ABC1 PF03109.16 EAX70500.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.1 3 1 1 4 4 4 0 ABC1 family TMP PF05017.14 EAX70501.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX70503.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70503.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX70503.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX70503.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX70504.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX70504.1 - 0.09 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) AAA_22 PF13401.6 EAX70505.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70505.1 - 3.2e-05 23.7 0.3 0.36 10.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX70505.1 - 0.0001 21.9 2.3 0.0001 21.9 2.3 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein ResIII PF04851.15 EAX70505.1 - 0.00034 20.6 4.7 0.0007 19.6 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70505.1 - 0.00052 19.8 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70505.1 - 0.002 18.0 1.6 0.0038 17.1 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70505.1 - 0.0053 16.4 2.8 0.013 15.1 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70505.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX70505.1 - 0.052 13.6 0.9 0.96 9.5 0.9 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX70505.1 - 0.064 12.8 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70505.1 - 0.089 13.2 0.5 0.69 10.3 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX70505.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70505.1 - 0.78 10.0 5.8 7.4 6.9 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX70507.1 - 1.9e-32 111.4 0.5 4.2e-32 110.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Trypan_PARP PF05887.11 EAX70508.1 - 0.092 12.7 7.4 0.12 12.4 7.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX70509.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70509.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX70511.1 - 2.2e-06 27.3 0.8 2.4e-06 27.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX70511.1 - 0.0027 16.6 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX70511.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX70511.1 - 0.022 14.7 0.7 0.047 13.7 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX70511.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70511.1 - 0.085 12.8 0.2 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX70511.1 - 0.22 11.7 1.8 1.7 8.9 0.1 2.5 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain DUF4107 PF13389.6 EAX70513.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70513.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4106 PF13388.6 EAX70514.1 - 1.5e-211 703.0 14.4 1.9e-211 702.7 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX70515.1 - 7.5e-100 333.4 7.8 8.4e-100 333.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX70515.1 - 0.044 13.3 0.4 0.052 13.0 0.4 1.2 1 0 0 1 1 1 0 Z1 domain PTR PF12789.7 EAX70517.1 - 0.0005 20.1 0.4 0.0005 20.1 0.4 2.8 3 0 0 3 3 3 1 Phage tail repeat like CREPT PF16566.5 EAX70517.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour YmaF PF12788.7 EAX70517.1 - 1.7 9.3 4.9 16 6.1 0.1 2.9 2 1 0 2 2 2 0 YmaF family APP_amyloid PF10515.9 EAX70519.1 - 0.087 13.3 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus DNA_pol_B_2 PF03175.13 EAX70520.1 - 3.5e-30 105.3 7.2 4.7e-30 104.9 7.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX70521.1 - 2.3e-07 30.5 2.4 3.1e-07 30.1 2.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70521.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70521.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70521.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70521.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70521.1 - 0.18 11.8 2.2 1.3 9.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70521.1 - 0.62 10.3 8.5 5.6 7.2 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Gly-zipper_Omp PF13488.6 EAX70522.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX70522.1 - 0.51 10.7 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PTR PF12789.7 EAX70523.1 - 1.1e-08 34.9 1.3 1.1e-08 34.9 1.3 5.3 4 2 1 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX70523.1 - 8.2 7.0 16.4 9.5 6.8 3.3 3.4 2 2 0 2 2 2 0 YmaF family Laminin_I PF06008.14 EAX70525.1 - 0.0002 21.2 5.2 0.00033 20.4 5.2 1.4 1 1 0 1 1 1 1 Laminin Domain I APG6_N PF17675.1 EAX70525.1 - 0.0023 18.5 0.8 0.003 18.1 0.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region GCN5L1 PF06320.13 EAX70525.1 - 0.013 15.7 0.5 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF3450 PF11932.8 EAX70525.1 - 0.015 14.6 5.3 0.02 14.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3552 PF12072.8 EAX70525.1 - 0.045 13.2 2.5 1.9 7.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) UPF0449 PF15136.6 EAX70525.1 - 0.053 14.0 5.2 3.3 8.2 5.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Sec34 PF04136.15 EAX70525.1 - 0.055 13.3 13.7 0.11 12.4 3.8 2.1 1 1 1 2 2 2 0 Sec34-like family YabA PF06156.13 EAX70525.1 - 0.08 13.6 0.6 0.91 10.2 0.3 2.0 1 1 1 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 EAX70525.1 - 0.093 12.6 6.9 0.15 11.8 6.9 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Prominin PF05478.11 EAX70525.1 - 0.13 10.1 1.9 0.15 9.9 1.9 1.0 1 0 0 1 1 1 0 Prominin JIP_LZII PF16471.5 EAX70525.1 - 0.27 11.4 2.1 12 6.2 0.5 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II CRR7 PF12095.8 EAX70525.1 - 0.31 11.5 4.7 10 6.6 0.3 2.6 1 1 2 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Jnk-SapK_ap_N PF09744.9 EAX70525.1 - 0.37 11.0 4.6 0.72 10.1 4.6 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SIKE PF05769.11 EAX70525.1 - 0.99 9.3 6.1 6.5 6.7 5.4 2.0 1 1 1 2 2 2 0 SIKE family DUF3839 PF12943.7 EAX70526.1 - 1.4e-128 427.4 7.0 1.6e-128 427.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70526.1 - 0.087 13.3 0.9 1.1 9.8 0.3 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX70527.1 - 0.00076 20.0 0.2 0.0022 18.5 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX70527.1 - 0.0074 15.8 0.2 0.99 8.9 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX70527.1 - 0.059 13.2 0.1 0.3 10.9 0.0 2.3 2 1 0 2 2 2 0 KilA-N domain Nab1 PF04902.12 EAX70529.1 - 0.018 15.5 1.6 0.021 15.2 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 PTR PF12789.7 EAX70532.1 - 4.2e-22 78.0 18.9 4.2e-16 58.7 1.9 4.7 6 0 0 6 6 6 3 Phage tail repeat like PTR PF12789.7 EAX70533.1 - 8.9e-11 41.7 20.8 1.7e-08 34.4 0.2 4.9 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX70533.1 - 0.0086 15.7 1.5 0.0086 15.7 1.5 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) DUF5017 PF16409.5 EAX70533.1 - 0.055 12.9 1.6 1.1 8.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) YmaF PF12788.7 EAX70533.1 - 0.26 11.8 7.8 23 5.6 0.1 3.7 3 1 0 3 3 3 0 YmaF family DUF4106 PF13388.6 EAX70534.1 - 7.9e-96 321.8 5.0 7.9e-96 321.8 5.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX70534.1 - 0.28 9.7 2.7 0.36 9.4 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Amidase02_C PF12123.8 EAX70535.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX70537.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX70538.1 - 1e-65 220.9 12.6 5e-64 215.4 12.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX70539.1 - 3.4e-59 196.8 37.7 1.4e-31 108.3 13.5 5.2 2 2 3 5 5 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX70539.1 - 0.036 13.8 0.9 0.078 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Peptidase_S66 PF02016.15 EAX70539.1 - 0.12 12.5 0.7 59 3.8 0.1 3.7 1 1 2 3 3 3 0 LD-carboxypeptidase N-terminal domain AviRa PF11599.8 EAX70539.1 - 0.2 11.1 4.0 0.51 9.8 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF3839 PF12943.7 EAX70540.1 - 1.2e-157 522.6 12.6 1.4e-157 522.4 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70540.1 - 0.18 12.3 6.5 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX70540.1 - 3.4 8.0 6.8 8.5 6.8 0.1 3.6 3 2 1 4 4 4 0 Tup N-terminal YvrJ PF12841.7 EAX70541.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family HC2 PF07382.11 EAX70542.1 - 9.9e-06 25.8 6.9 1.2e-05 25.5 6.9 1.0 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX70542.1 - 0.008 16.3 0.2 0.01 16.0 0.2 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF4108 PF13390.6 EAX70543.1 - 7.6e-60 201.0 7.7 8.4e-60 200.8 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70544.1 - 0.55 10.2 5.3 0.77 9.7 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RNA_polI_A34 PF08208.11 EAX70544.1 - 5.9 6.9 18.9 6 6.9 18.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2939 PF11159.8 EAX70546.1 - 0.017 15.6 0.5 0.022 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70546.1 - 1.4 8.9 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX70547.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX70548.1 - 0.21 11.5 3.5 0.17 11.8 0.3 2.2 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX70549.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX70551.1 - 7.9e-78 261.2 9.7 1e-77 260.9 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70551.1 - 0.17 11.8 1.6 0.65 9.8 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_D5 PF03288.16 EAX70552.1 - 3.9e-05 24.1 2.2 0.0002 21.8 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like YpsA PF06908.11 EAX70552.1 - 0.042 13.8 0.3 0.087 12.8 0.2 1.5 2 0 0 2 2 2 0 YspA SLOG family RFX_DNA_binding PF02257.15 EAX70552.1 - 0.069 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70552.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX70553.1 - 1.2e-57 193.8 6.1 1.4e-57 193.7 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX70554.1 - 1.6e-11 44.5 0.4 3.1e-11 43.5 0.1 1.7 2 0 0 2 2 2 1 MULE transposase domain DUF5365 PF17326.2 EAX70554.1 - 0.053 13.9 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX70554.1 - 0.08 13.3 0.4 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 PWI domain DUF4107 PF13389.6 EAX70555.1 - 4.9e-66 221.9 13.0 2.3e-64 216.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX70556.1 - 2.8e-16 59.5 0.5 3.3e-16 59.2 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70556.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) TMP PF05017.14 EAX70563.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF2666 PF10869.8 EAX70564.1 - 0.013 15.7 1.7 0.024 14.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX70565.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX70565.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PTR PF12789.7 EAX70566.1 - 1.2e-16 60.5 1.9 1.2e-16 60.5 1.9 5.3 4 2 2 6 6 5 1 Phage tail repeat like DUF3391 PF11871.8 EAX70566.1 - 0.0088 16.6 3.3 0.13 12.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX70566.1 - 1.4 8.5 20.1 0.087 12.4 6.4 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) RNA12 PF10443.9 EAX70566.1 - 3.4 6.3 8.8 1.1 8.0 3.0 2.0 2 0 0 2 2 2 0 RNA12 protein DUF4350 PF14258.6 EAX70567.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) CD99L2 PF12301.8 EAX70568.1 - 0.074 13.3 0.6 0.14 12.4 0.1 1.7 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF347 PF03988.12 EAX70568.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pox_A32 PF04665.12 EAX70569.1 - 3.3e-07 30.0 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70569.1 - 0.0045 16.7 0.1 0.006 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70569.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70569.1 - 0.063 13.0 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70569.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70569.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70569.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) GPS2_interact PF15784.5 EAX70570.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70570.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain AAA_22 PF13401.6 EAX70576.1 - 3.6e-05 24.1 0.1 0.00023 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70576.1 - 7.4e-05 22.5 0.3 0.27 10.9 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX70576.1 - 7.7e-05 22.8 2.8 0.00013 22.0 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70576.1 - 0.00037 20.3 0.1 0.00051 19.9 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70576.1 - 0.00092 19.1 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70576.1 - 0.0084 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70576.1 - 0.055 12.9 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX70576.1 - 0.066 13.0 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX70576.1 - 0.071 13.5 0.1 0.41 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70576.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX70576.1 - 0.2 11.9 4.3 6.2 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX70577.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70577.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta FAS_N PF17828.1 EAX70578.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX70579.1 - 0.0071 16.7 0.3 0.008 16.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) Gly-zipper_Omp PF13488.6 EAX70580.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX70580.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX70580.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Stb3 PF10330.9 EAX70581.1 - 0.098 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative Sin3 binding protein RTT107_BRCT_6 PF16771.5 EAX70581.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PSP PF04046.16 EAX70583.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70584.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat GGDEF PF00990.21 EAX70585.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.5 1 1 1 2 2 2 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX70585.1 - 0.07 13.4 9.3 0.1 12.9 9.3 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX70585.1 - 8.1 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70586.1 - 7.6e-58 194.5 6.0 8.4e-58 194.4 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX70587.1 - 3.9e-72 241.7 3.6 5.1e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX70589.1 - 1.7e-13 50.8 0.1 3.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX70589.1 - 0.086 12.5 1.1 0.15 11.7 1.1 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX70589.1 - 0.42 10.9 5.6 0.95 9.7 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX70589.1 - 0.48 10.2 5.2 0.74 9.6 5.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2939 PF11159.8 EAX70590.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70590.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX70592.1 - 3.8e-63 211.7 6.0 4.2e-63 211.6 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70593.1 - 0.12 12.3 3.6 0.15 11.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OAD_gamma PF04277.13 EAX70593.1 - 6.1 7.5 4.9 6.6 7.4 4.9 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pox_D5 PF03288.16 EAX70594.1 - 1.5e-05 25.4 2.2 7.8e-05 23.1 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70594.1 - 0.078 13.6 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX70595.1 - 4.4e-64 214.7 6.2 4.9e-64 214.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX70596.1 - 0.18 11.7 3.2 0.23 11.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1493 PF07377.12 EAX70597.1 - 0.092 13.2 0.4 0.19 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70597.1 - 0.67 10.0 3.3 13 5.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX70599.1 - 6.2e-05 22.6 3.6 6.3e-05 22.5 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX70599.1 - 0.004 17.2 0.1 0.0094 16.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX70599.1 - 0.031 13.5 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAX70600.1 - 4e-29 101.8 7.0 5.5e-29 101.3 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX70600.1 - 0.13 11.5 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II KilA-N PF04383.13 EAX70601.1 - 2.3e-41 140.2 1.5 3.7e-41 139.5 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX70601.1 - 0.85 9.7 3.9 2.3 8.3 0.4 2.3 2 0 0 2 2 2 0 Tumour suppressor protein PTR PF12789.7 EAX70602.1 - 1.8e-30 104.8 12.4 1.8e-30 104.8 12.4 4.1 4 1 0 4 4 4 1 Phage tail repeat like Ank_2 PF12796.7 EAX70603.1 - 1.2e-06 29.0 0.0 1.4e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX70603.1 - 3.3e-05 24.3 0.0 4.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX70603.1 - 0.00048 20.4 0.0 0.00082 19.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX70603.1 - 0.0046 17.3 0.0 0.091 13.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX70603.1 - 0.1 13.1 0.0 7.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Amidase02_C PF12123.8 EAX70604.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX70605.1 - 4.2e-08 32.9 0.4 5e-08 32.7 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70605.1 - 0.006 16.2 0.1 0.0061 16.2 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX70605.1 - 0.079 12.9 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX70605.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein T5orf172 PF10544.9 EAX70606.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX70607.1 - 5.7e-23 81.5 4.4 7.1e-23 81.2 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral SRP54 PF00448.22 EAX70608.1 - 0.079 12.6 1.4 2.1 8.0 0.2 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain SHIRT PF18655.1 EAX70608.1 - 0.1 13.2 0.5 0.1 13.2 0.5 3.2 4 1 1 5 5 5 0 SHIRT domain MBD PF01429.19 EAX70608.1 - 0.43 10.3 2.5 60 3.4 0.1 3.2 3 0 0 3 3 3 0 Methyl-CpG binding domain Synuclein PF01387.17 EAX70608.1 - 10 6.4 7.9 17 5.6 7.9 1.4 1 0 0 1 1 1 0 Synuclein Trypan_PARP PF05887.11 EAX70609.1 - 0.51 10.3 13.2 0.56 10.2 13.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX70609.1 - 3.6 8.0 6.1 3.9 7.9 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX70611.1 - 3.1e-157 521.2 12.7 4.1e-157 520.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX70611.1 - 0.07 13.5 0.6 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX70611.1 - 0.093 13.2 5.9 2.1 8.9 0.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX70611.1 - 0.14 12.4 2.2 13 6.1 0.1 3.7 3 1 1 4 4 4 0 Tup N-terminal Spo0A_C PF08769.11 EAX70612.1 - 0.078 13.1 0.1 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PSP PF04046.16 EAX70613.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70614.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX70616.1 - 2e-42 143.6 1.4 2.5e-42 143.2 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70616.1 - 0.006 17.2 0.1 0.02 15.5 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX70617.1 - 9.8e-80 267.5 10.4 1.3e-79 267.1 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX70619.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70619.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70619.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70619.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX70620.1 - 6.6e-06 26.6 0.3 1.7e-05 25.3 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70620.1 - 0.011 15.6 0.2 0.053 13.4 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX70620.1 - 0.014 15.0 1.2 0.13 11.7 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX70621.1 - 3.3e-153 508.1 11.1 3.7e-153 507.9 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70621.1 - 0.099 12.5 0.8 0.38 10.6 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX70621.1 - 0.29 11.4 2.5 1.4 9.3 0.0 2.8 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX70621.1 - 0.59 10.6 5.6 6.1 7.4 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX70623.1 - 7.6e-242 802.8 23.5 3.8e-240 797.3 23.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX70623.1 - 0.00047 20.4 0.1 0.02 15.2 0.3 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX70623.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Caprin-1_dimer PF18293.1 EAX70623.1 - 0.046 14.2 0.4 0.097 13.2 0.4 1.6 1 0 0 1 1 1 0 Caprin-1 dimerization domain Peptidase_S28 PF05577.12 EAX70623.1 - 0.73 8.6 4.6 1.1 8.0 4.6 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 KilA-N PF04383.13 EAX70624.1 - 4.1e-37 126.4 0.8 8.7e-37 125.4 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX70624.1 - 0.0034 17.5 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX70624.1 - 0.11 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) PTR PF12789.7 EAX70626.1 - 0.13 12.4 9.2 0.19 11.8 0.2 3.7 4 0 0 4 4 4 0 Phage tail repeat like YmaF PF12788.7 EAX70626.1 - 0.48 11.0 4.2 6 7.5 2.1 2.9 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX70626.1 - 1 9.7 14.7 3.3 8.1 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX70627.1 - 6.8e-10 38.4 3.6 3.5e-09 36.1 3.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX70627.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Parathyroid PF01279.17 EAX70628.1 - 0.021 15.4 0.0 0.046 14.3 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF2939 PF11159.8 EAX70629.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70629.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Gly-zipper_Omp PF13488.6 EAX70630.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX70630.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX70630.1 - 0.74 10.0 5.4 1.2 9.2 5.4 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif JMY PF15871.5 EAX70632.1 - 0.0078 15.6 0.8 0.011 15.0 0.8 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX70632.1 - 0.15 12.1 1.0 0.34 10.9 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) DUF4108 PF13390.6 EAX70635.1 - 4e-58 195.4 4.2 4.5e-58 195.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX70636.1 - 5.7e-19 68.0 1.1 8.7e-19 67.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70636.1 - 0.018 15.6 0.0 0.06 14.0 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX70637.1 - 2.4e-111 371.0 6.5 2.8e-111 370.8 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX70637.1 - 0.044 13.3 0.3 0.052 13.0 0.3 1.2 1 0 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX70639.1 - 6.9e-34 116.1 0.3 6.9e-34 116.1 0.3 1.9 2 1 0 2 2 2 1 KilA-N domain S8_pro-domain PF16470.5 EAX70639.1 - 0.24 12.2 2.3 0.39 11.5 0.4 2.1 2 0 0 2 2 2 0 Peptidase S8 pro-domain Cep57_MT_bd PF06657.13 EAX70639.1 - 0.4 11.2 6.5 2.1 8.8 2.0 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3574 PF12098.8 EAX70640.1 - 0.14 12.0 0.9 0.2 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) ATP-synt_DE PF00401.20 EAX70640.1 - 0.42 10.9 4.8 6.6 7.1 0.3 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TMP PF05017.14 EAX70641.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70642.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX70644.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX70645.1 - 2.6e-10 40.6 0.2 7e-10 39.2 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX70645.1 - 0.007 15.3 0.2 0.013 14.4 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX70645.1 - 0.008 15.9 0.4 0.042 13.5 0.3 1.9 1 1 1 2 2 2 1 Transposase FAR1 PF03101.15 EAX70645.1 - 0.084 13.6 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Ribosomal_S6e PF01092.19 EAX70647.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e Meiosis_expr PF15163.6 EAX70648.1 - 0.031 14.9 1.9 0.033 14.9 0.8 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX70648.1 - 5.9 6.9 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family TMP PF05017.14 EAX70649.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX70651.1 - 3.6e-66 223.1 2.1 4.2e-66 222.8 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ArsA_ATPase PF02374.15 EAX70651.1 - 0.045 12.9 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase PapD_N PF00345.20 EAX70652.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70652.1 - 0.029 14.4 0.3 0.038 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX70652.1 - 0.052 13.6 0.2 0.063 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX70653.1 - 0.031 14.7 1.0 0.035 14.5 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70653.1 - 2.4 7.1 4.5 2.6 7.0 4.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX70653.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX70653.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PSP PF04046.16 EAX70654.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX70655.1 - 0.17 12.6 4.9 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX70659.1 - 0.0032 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX70659.1 - 0.2 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4378 PF14309.6 EAX70660.1 - 0.031 14.6 0.1 0.16 12.3 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX70660.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 La domain Pox_A32 PF04665.12 EAX70661.1 - 6.9e-08 32.2 0.3 8.2e-08 32.0 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70661.1 - 0.0053 16.4 0.1 0.0053 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX70661.1 - 0.06 13.3 0.3 0.51 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX70661.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4107 PF13389.6 EAX70662.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_D5 PF03288.16 EAX70663.1 - 8e-06 26.3 0.5 1.1e-05 25.8 0.5 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70663.1 - 0.011 16.3 0.1 0.015 15.9 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70663.1 - 0.025 14.5 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX70664.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX70665.1 - 0.0099 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DAO_C PF16901.5 EAX70665.1 - 0.06 13.2 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Ly49 PF08391.10 EAX70665.1 - 0.33 11.3 2.6 0.34 11.3 2.6 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Mid2 PF04478.12 EAX70666.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX70666.1 - 0.00045 19.9 2.0 0.00072 19.3 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX70666.1 - 0.00051 20.2 0.0 0.00059 20.0 0.0 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX70666.1 - 0.0034 17.3 0.5 0.0056 16.6 0.3 1.4 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX70666.1 - 0.0036 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX70666.1 - 0.0046 17.2 0.8 0.0072 16.5 0.8 1.5 1 1 0 1 1 1 1 Glycophorin A ECSCR PF15820.5 EAX70666.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 EAX70666.1 - 0.022 15.0 0.2 0.03 14.6 0.2 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX70666.1 - 0.034 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MtrF PF09472.10 EAX70666.1 - 0.04 13.3 3.5 0.068 12.6 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 EAX70666.1 - 0.048 14.5 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 EAX70666.1 - 0.057 12.5 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Gemini_mov PF01708.16 EAX70666.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF5385 PF17359.2 EAX70666.1 - 0.075 12.6 1.0 0.88 9.1 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) SKG6 PF08693.10 EAX70666.1 - 0.078 12.4 4.0 0.14 11.6 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 EAX70666.1 - 0.085 12.9 0.5 0.12 12.3 0.4 1.3 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2207 PF09972.9 EAX70666.1 - 0.095 11.4 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Otopetrin PF03189.13 EAX70666.1 - 0.1 11.4 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Cortexin PF11057.8 EAX70666.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney ODV-E18 PF10717.9 EAX70666.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 EAX70666.1 - 0.2 10.0 2.6 0.29 9.5 2.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) PapD_N PF00345.20 EAX70668.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX70669.1 - 0.027 14.9 0.6 0.037 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70669.1 - 0.6 9.1 3.8 0.66 9.0 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein RR_TM4-6 PF06459.12 EAX70669.1 - 1.9 8.2 9.2 1.9 8.3 9.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 EAX70669.1 - 2.1 8.4 6.3 2.4 8.1 6.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HTH_32 PF13565.6 EAX70669.1 - 2.7 8.7 7.6 6.1 7.5 7.6 1.8 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX70670.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX70671.1 - 6.3e-72 241.0 4.3 8.2e-72 240.7 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX70673.1 - 3.2e-43 147.1 2.9 3.6e-43 146.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX70673.1 - 0.14 11.2 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PEP-utilizers_C PF02896.18 EAX70676.1 - 1.5e-44 152.3 0.0 1.7e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ank_4 PF13637.6 EAX70677.1 - 4.4e-32 110.1 0.1 8.3e-12 45.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX70677.1 - 2e-31 108.4 0.0 1.7e-15 57.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX70677.1 - 5.5e-30 103.0 0.8 1.9e-09 37.6 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX70677.1 - 1.5e-24 85.3 0.1 2.7e-05 24.4 0.0 4.8 5 0 0 5 5 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX70677.1 - 6.7e-21 72.2 0.0 0.00092 19.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Wtap PF17098.5 EAX70677.1 - 0.00023 21.1 1.8 0.0004 20.3 1.8 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family FapA PF03961.13 EAX70677.1 - 0.0012 17.6 6.3 0.0017 17.0 6.3 1.4 1 0 0 1 1 1 1 Flagellar Assembly Protein A APG6_N PF17675.1 EAX70677.1 - 0.0017 18.9 10.6 0.0033 18.0 10.6 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 EAX70677.1 - 0.0037 16.2 8.6 0.0067 15.4 8.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein GBP_C PF02841.14 EAX70677.1 - 0.009 15.5 6.6 0.013 15.0 6.6 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ATG16 PF08614.11 EAX70677.1 - 0.01 16.1 6.8 0.016 15.4 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EAX70677.1 - 0.02 14.4 10.3 0.029 13.9 10.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 EAX70677.1 - 0.021 15.1 9.2 0.037 14.4 9.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EAX70677.1 - 0.023 14.3 3.1 0.028 14.0 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 EAX70677.1 - 0.024 15.4 3.9 0.047 14.4 3.5 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ABC_tran_CTD PF16326.5 EAX70677.1 - 0.029 14.6 6.9 0.076 13.3 6.9 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Het-C PF07217.11 EAX70677.1 - 0.031 12.8 3.5 0.045 12.3 3.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C WXG100 PF06013.12 EAX70677.1 - 0.052 13.8 3.8 0.23 11.7 2.9 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Allexi_40kDa PF05549.11 EAX70677.1 - 0.083 12.4 4.0 0.13 11.7 4.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMF_TATA_bd PF12325.8 EAX70677.1 - 0.11 12.7 11.9 0.19 11.9 8.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAX70677.1 - 0.16 11.3 1.3 0.23 10.8 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 EAX70677.1 - 0.21 11.5 3.7 0.53 10.2 3.7 1.7 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit COG2 PF06148.11 EAX70677.1 - 0.21 11.7 7.6 0.097 12.8 3.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GIT1_C PF12205.8 EAX70677.1 - 0.31 11.2 6.5 0.49 10.5 6.0 1.6 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term FliJ PF02050.16 EAX70677.1 - 0.34 11.1 9.9 0.054 13.7 5.5 1.9 2 0 0 2 2 1 0 Flagellar FliJ protein Lectin_N PF03954.14 EAX70677.1 - 0.35 10.6 5.0 0.66 9.7 5.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Prefoldin PF02996.17 EAX70677.1 - 0.4 10.6 14.8 0.35 10.8 5.8 3.6 1 1 2 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.13 EAX70677.1 - 0.42 11.3 8.7 1.3 9.7 5.4 2.6 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 EAX70677.1 - 0.46 9.5 9.3 0.62 9.1 9.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 EAX70677.1 - 0.59 10.3 5.0 1.2 9.2 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Adenine_glyco PF03352.13 EAX70677.1 - 0.59 9.9 4.6 1.2 8.8 4.6 1.6 1 1 0 1 1 1 0 Methyladenine glycosylase Swi5 PF07061.11 EAX70677.1 - 0.61 10.2 13.6 0.23 11.5 7.9 2.5 1 1 1 2 2 2 0 Swi5 DSPc PF00782.20 EAX70677.1 - 0.64 9.8 5.1 14 5.5 2.1 2.9 1 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain DUF1664 PF07889.12 EAX70677.1 - 0.65 10.0 8.1 3.1 7.8 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 EAX70677.1 - 0.69 9.9 9.7 1.1 9.2 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc24 PF08286.11 EAX70677.1 - 1.1 9.6 14.8 0.65 10.3 9.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Muted PF14942.6 EAX70677.1 - 1.1 9.6 14.8 1.5 9.1 13.3 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 EAX70677.1 - 1.2 9.7 9.4 9.6 6.8 8.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF349 PF03993.12 EAX70677.1 - 1.3 9.4 6.7 8 6.8 3.6 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) LPP PF04728.13 EAX70677.1 - 1.4 9.4 6.6 2.5 8.6 4.3 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EAX70677.1 - 1.4 9.2 6.1 1.6 9.0 2.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 EAX70677.1 - 1.5 9.1 6.0 1.7e+02 2.6 6.0 2.7 1 1 0 1 1 1 0 Rx N-terminal domain GTP-bdg_M PF16360.5 EAX70677.1 - 1.7 9.3 4.7 12 6.6 0.7 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region YtxH PF12732.7 EAX70677.1 - 1.9 9.1 7.0 32 5.1 7.0 2.7 1 1 0 1 1 1 0 YtxH-like protein CC2-LZ PF16516.5 EAX70677.1 - 2.3 8.6 11.5 4.3 7.7 8.9 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Cnd1 PF12717.7 EAX70677.1 - 4 7.4 12.7 0.24 11.4 1.0 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Bap31_Bap29_C PF18035.1 EAX70677.1 - 5 7.2 10.9 7.2 6.7 9.9 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CCDC-167 PF15188.6 EAX70677.1 - 5.5 7.4 10.3 2.1 8.8 7.5 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 NYD-SP28 PF14772.6 EAX70677.1 - 8.5 6.5 15.2 0.98 9.5 5.7 2.4 1 1 1 2 2 2 0 Sperm tail Cytochrom_B562 PF07361.11 EAX70677.1 - 8.9 7.0 10.9 5.6 7.7 2.5 3.1 2 1 2 4 4 3 0 Cytochrome b562 AAA_22 PF13401.6 EAX70678.1 - 2.5e-05 24.6 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70678.1 - 3.3e-05 23.7 0.4 0.4 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX70678.1 - 4.4e-05 23.1 2.2 4.4e-05 23.1 2.2 2.2 1 1 1 3 3 3 1 Poxvirus A32 protein DEAD PF00270.29 EAX70678.1 - 0.0006 19.6 0.1 0.0012 18.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX70678.1 - 0.00087 19.3 5.3 0.0013 18.8 4.5 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX70678.1 - 0.0031 17.2 3.0 0.0088 15.7 0.6 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX70678.1 - 0.0079 16.0 3.4 0.0093 15.8 1.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX70678.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX70678.1 - 0.042 14.3 0.1 0.43 11.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70678.1 - 0.073 12.6 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX70678.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX70678.1 - 0.5 10.6 4.9 7.1 7.0 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70678.1 - 1.8 9.3 11.8 0.094 13.4 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Amidase02_C PF12123.8 EAX70679.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX70681.1 - 4.3e-25 88.6 5.0 6.2e-25 88.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX70681.1 - 0.052 13.8 0.4 0.21 11.9 0.0 2.0 1 1 1 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX70682.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70682.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70682.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70682.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PG_binding_2 PF08823.11 EAX70683.1 - 0.015 15.6 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF4108 PF13390.6 EAX70685.1 - 1.8e-61 206.3 8.3 2e-61 206.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX70688.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain YmaF PF12788.7 EAX70690.1 - 0.0049 17.4 2.9 0.14 12.7 0.3 2.1 1 1 1 2 2 2 2 YmaF family AAL_decarboxy PF03306.13 EAX70690.1 - 0.12 11.6 0.4 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase Phage_fiber PF03335.13 EAX70690.1 - 1.2 9.5 8.6 6 7.3 1.5 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX70691.1 - 1.3e-131 437.3 11.0 1.5e-131 437.2 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70691.1 - 0.17 12.4 2.9 1.4 9.4 1.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX70691.1 - 0.28 11.5 3.4 1.4 9.3 0.0 2.9 2 1 1 3 3 3 0 Rx N-terminal domain DUF2897 PF11446.8 EAX70693.1 - 1 9.3 3.2 2.1 8.3 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX70694.1 - 2.1e-41 140.3 1.0 3.9e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX70694.1 - 0.011 15.1 0.2 0.043 13.1 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX70694.1 - 0.15 12.6 2.0 1.6 9.3 0.4 2.4 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 TMP PF05017.14 EAX70695.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX70696.1 - 1.4e-32 111.5 21.2 1.1e-31 108.6 17.1 4.0 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX70696.1 - 0.024 14.4 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Lipid_DES PF08557.10 EAX70697.1 - 1.9 8.0 4.4 0.54 9.8 1.0 1.9 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) PadR PF03551.14 EAX70699.1 - 0.048 13.6 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX70700.1 - 2.6e-102 341.4 6.0 3e-102 341.2 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX70700.1 - 0.043 13.3 0.3 0.061 12.8 0.3 1.3 1 1 0 1 1 1 0 Z1 domain DUF3781 PF12636.7 EAX70701.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX70703.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70703.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX70704.1 - 0.0099 15.6 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX70705.1 - 9.8e-150 496.7 12.9 1.1e-149 496.5 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70705.1 - 0.028 14.3 2.0 0.21 11.5 2.1 2.1 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX70705.1 - 0.2 12.2 9.5 1.6 9.2 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX70705.1 - 0.33 11.5 4.7 0.65 10.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX70705.1 - 0.63 10.4 4.2 4.1 7.8 0.1 3.1 3 1 0 3 3 3 0 Tup N-terminal Rx_N PF18052.1 EAX70705.1 - 1.6 9.1 4.7 1.3 9.3 0.2 2.9 2 2 1 3 3 3 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX70706.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70706.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70706.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70706.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70706.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX70706.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX70707.1 - 1.4e-125 417.6 6.6 1.7e-125 417.3 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70707.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase Z1 PF10593.9 EAX70707.1 - 0.019 14.4 0.3 0.032 13.7 0.3 1.6 1 1 0 1 1 1 0 Z1 domain DNA_pol_B_2 PF03175.13 EAX70708.1 - 1.6e-29 103.1 7.1 2.7e-29 102.4 7.1 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX70709.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70709.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70709.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70709.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX70710.1 - 1.2e-25 90.4 3.8 1.7e-25 89.9 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX70711.1 - 1.1e-07 31.7 0.0 2.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain GPS2_interact PF15784.5 EAX70712.1 - 0.066 13.7 1.3 0.098 13.1 1.3 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70712.1 - 0.082 11.9 0.1 0.083 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX70713.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX70714.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX70714.1 - 0.13 12.6 0.6 0.24 11.8 0.1 1.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta FliJ PF02050.16 EAX70715.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein PWI PF01480.17 EAX70716.1 - 0.029 14.7 0.1 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 PWI domain KilA-N PF04383.13 EAX70717.1 - 1.3e-34 118.4 1.1 2e-34 117.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain TMP PF05017.14 EAX70719.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat TMCO5 PF14992.6 EAX70721.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.0 1 0 0 1 1 1 0 TMCO5 family bZIP_2 PF07716.15 EAX70721.1 - 0.025 14.7 0.4 0.07 13.2 0.4 1.7 1 1 0 1 1 1 0 Basic region leucine zipper DUF3416 PF11896.8 EAX70721.1 - 0.11 12.7 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Pox_D5 PF03288.16 EAX70724.1 - 0.00012 22.5 2.3 0.00071 20.0 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX70724.1 - 0.036 13.2 1.2 0.049 12.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4106 PF13388.6 EAX70725.1 - 6.9e-233 773.3 35.4 4.4e-152 507.2 9.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX70725.1 - 0.008 16.5 0.1 0.41 11.0 0.2 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX70725.1 - 0.077 12.8 1.1 0.092 12.6 0.2 1.5 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) PNPase PF03726.14 EAX70725.1 - 5.5 7.6 5.4 13 6.3 1.6 2.3 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PapD_N PF00345.20 EAX70726.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol3_a_NII PF11490.8 EAX70726.1 - 0.88 9.5 6.3 1.6 8.6 4.9 1.9 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II T5orf172 PF10544.9 EAX70728.1 - 8.5e-06 26.3 0.2 3.4e-05 24.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX70728.1 - 0.13 12.1 0.4 0.79 9.6 0.1 2.3 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX70729.1 - 2.2e-07 30.6 0.5 1.5e-06 27.8 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX70729.1 - 0.048 13.8 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX70729.1 - 0.063 12.9 0.1 1.4 8.5 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX70729.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase PTR PF12789.7 EAX70730.1 - 3.2e-09 36.7 18.9 1.5e-08 34.5 0.3 4.0 4 1 0 4 4 4 2 Phage tail repeat like DUF2939 PF11159.8 EAX70731.1 - 0.045 14.2 0.2 0.058 13.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) THF_DHG_CYH PF00763.23 EAX70731.1 - 0.14 12.5 2.3 0.2 12.0 2.3 1.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain FAS_N PF17828.1 EAX70732.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta SHIRT PF18655.1 EAX70733.1 - 0.14 12.8 0.5 0.14 12.8 0.5 3.3 3 1 1 4 4 4 0 SHIRT domain Staufen_C PF16482.5 EAX70733.1 - 0.78 9.9 8.3 0.32 11.2 1.4 2.9 1 1 2 3 3 3 0 Staufen C-terminal domain Macoilin PF09726.9 EAX70733.1 - 2.2 6.8 11.3 2.6 6.5 11.3 1.1 1 0 0 1 1 1 0 Macoilin family DNA_pol_B_2 PF03175.13 EAX70734.1 - 7.8e-09 34.9 0.1 7.8e-09 34.9 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF5365 PF17326.2 EAX70735.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX70735.1 - 0.028 14.7 0.3 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain PTR PF12789.7 EAX70736.1 - 1.5e-24 85.8 12.8 1.5e-24 85.8 12.8 3.7 4 1 1 5 5 4 1 Phage tail repeat like DUF3391 PF11871.8 EAX70736.1 - 0.16 12.5 2.7 13 6.4 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4108 PF13390.6 EAX70738.1 - 3.7e-62 208.5 8.2 4.2e-62 208.3 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TFCD_C PF12612.8 EAX70740.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Pox_A32 PF04665.12 EAX70741.1 - 2.9e-07 30.2 2.2 4.5e-07 29.6 1.1 1.8 2 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX70741.1 - 2.1e-05 24.3 0.3 0.25 11.1 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70741.1 - 2.2e-05 24.8 0.2 0.0002 21.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX70741.1 - 0.00055 20.0 3.4 0.0014 18.7 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX70741.1 - 0.0015 18.2 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX70741.1 - 0.0021 17.9 0.4 0.0064 16.3 0.4 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX70741.1 - 0.0041 16.9 0.1 0.0077 16.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX70741.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX70741.1 - 0.022 15.2 0.1 0.19 12.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70741.1 - 0.081 12.5 0.0 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX70741.1 - 0.095 12.1 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX70741.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX70741.1 - 0.35 11.1 3.8 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX70742.1 - 2.7e-34 117.4 1.2 3.7e-34 117.0 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70742.1 - 0.043 14.4 0.0 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX70743.1 - 6.7e-81 271.3 10.9 8.8e-81 270.9 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX70745.1 - 4.8e-56 188.7 4.0 5.3e-56 188.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX70746.1 - 0.035 14.4 4.1 0.034 14.4 4.1 1.0 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX70746.1 - 4.4 7.3 5.6 4.7 7.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX70750.1 - 4.4e-07 29.6 0.1 9e-07 28.6 0.0 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein WEMBL PF05701.11 EAX70751.1 - 0.017 13.8 1.0 0.02 13.6 1.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Meiosis_expr PF15163.6 EAX70751.1 - 0.064 13.9 0.7 0.11 13.2 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed FYVE_2 PF02318.16 EAX70752.1 - 0.024 14.9 0.3 0.047 13.9 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4795 PF16043.5 EAX70754.1 - 0.0062 16.2 1.6 0.014 15.0 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PTR PF12789.7 EAX70754.1 - 0.025 14.6 1.8 0.025 14.6 1.8 3.4 4 1 0 4 4 4 0 Phage tail repeat like YmaF PF12788.7 EAX70754.1 - 2.3 8.8 5.7 25 5.5 0.1 3.3 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX70754.1 - 3.6 8.0 16.2 3.9 7.9 1.1 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DAGK_acc PF00609.19 EAX70755.1 - 5.2e-27 95.1 0.0 8.8e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EAX70755.1 - 4.4e-21 74.8 0.0 7.2e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF2477 PF10631.9 EAX70755.1 - 0.0011 19.7 3.5 0.04 14.6 3.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2477) Nab1 PF04902.12 EAX70756.1 - 0.017 15.5 1.6 0.021 15.2 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 Dynactin_p22 PF07426.11 EAX70757.1 - 0.0003 20.7 3.5 0.093 12.6 0.3 2.2 1 1 1 2 2 2 2 Dynactin subunit p22 WXG100 PF06013.12 EAX70757.1 - 0.0095 16.1 0.4 0.026 14.8 0.4 1.8 1 1 0 1 1 1 1 Proteins of 100 residues with WXG His_Phos_2 PF00328.22 EAX70757.1 - 0.015 14.7 0.3 0.015 14.7 0.3 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) NEMO PF11577.8 EAX70757.1 - 0.017 15.1 3.6 0.088 12.8 1.0 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO GH97_N PF14508.6 EAX70757.1 - 0.02 14.4 0.3 0.02 14.4 0.3 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal T3SSipB PF16535.5 EAX70757.1 - 0.041 14.4 0.4 0.048 14.1 0.4 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB KxDL PF10241.9 EAX70757.1 - 0.055 13.8 1.7 0.13 12.5 1.7 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Pox_A_type_inc PF04508.12 EAX70757.1 - 0.097 12.6 4.7 1.1 9.2 0.8 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ArAE_2_N PF10337.9 EAX70757.1 - 0.1 11.6 0.4 0.11 11.5 0.4 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CdvA PF18822.1 EAX70757.1 - 0.16 11.8 5.5 0.31 10.9 5.5 1.4 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Fib_alpha PF08702.10 EAX70757.1 - 0.17 12.1 3.6 0.19 11.9 3.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EAX70757.1 - 0.38 9.3 3.8 0.39 9.3 3.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_22 PF13401.6 EAX70759.1 - 5.5e-05 23.5 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX70759.1 - 6.5e-05 23.0 2.6 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70759.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70759.1 - 0.00077 19.3 0.8 0.0022 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70759.1 - 0.0027 17.5 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX70759.1 - 0.0075 16.6 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70759.1 - 0.052 13.0 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX70759.1 - 0.091 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70759.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX70759.1 - 0.19 12.0 4.1 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX70759.1 - 0.77 10.2 4.2 0.38 11.2 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3447 PF11929.8 EAX70761.1 - 3.6e-25 87.7 6.1 3.6e-25 87.7 6.1 3.9 2 2 3 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX70761.1 - 4.7e-10 39.9 1.3 1.3e-06 28.9 0.2 2.7 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX70761.1 - 2.6e-09 37.2 0.2 3.7e-07 30.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX70761.1 - 1.3e-08 34.9 0.2 7.2e-08 32.5 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX70761.1 - 1.2e-06 28.9 1.1 0.0097 16.5 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX70761.1 - 0.00034 20.8 3.7 0.0055 17.1 0.1 4.2 5 0 0 5 5 5 1 Ankyrin repeat DUF3839 PF12943.7 EAX70762.1 - 1.1e-155 516.2 12.5 1.3e-155 515.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70762.1 - 0.11 13.0 5.0 2 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX70763.1 - 2.9e-32 110.8 0.6 6.4e-32 109.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Csm1_N PF18504.1 EAX70765.1 - 0.00024 21.4 3.6 0.033 14.5 0.0 2.3 2 0 0 2 2 2 2 Csm1 N-terminal domain DHR10 PF18595.1 EAX70765.1 - 0.0013 18.8 8.1 0.03 14.4 6.9 2.0 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain Spc7 PF08317.11 EAX70765.1 - 0.0046 15.9 3.9 0.005 15.8 3.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX70765.1 - 0.0092 15.8 1.3 0.0092 15.8 1.3 2.5 2 1 2 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CC2-LZ PF16516.5 EAX70765.1 - 0.011 16.1 3.1 0.017 15.5 3.1 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF641 PF04859.12 EAX70765.1 - 0.012 16.0 3.3 0.016 15.5 3.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FAM76 PF16046.5 EAX70765.1 - 0.045 13.1 4.1 0.048 13.0 4.1 1.1 1 0 0 1 1 1 0 FAM76 protein GNT-I PF03071.15 EAX70765.1 - 0.056 12.2 0.8 0.069 11.9 0.8 1.1 1 0 0 1 1 1 0 GNT-I family CT_C_D PF02682.16 EAX70765.1 - 0.057 13.1 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D bZIP_1 PF00170.21 EAX70765.1 - 0.058 13.5 4.5 6.9 6.9 3.5 2.5 2 1 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.9 EAX70765.1 - 0.099 11.7 4.7 0.11 11.6 4.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PTR PF12789.7 EAX70766.1 - 9.9e-51 169.7 32.6 6.7e-35 118.9 16.1 4.2 5 2 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX70766.1 - 0.013 15.2 0.1 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) T5orf172 PF10544.9 EAX70767.1 - 6.8e-06 26.6 0.3 2.1e-05 25.0 0.3 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX70767.1 - 0.01 15.4 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX70767.1 - 0.056 13.3 0.1 0.37 10.6 0.0 2.3 2 1 0 2 2 2 0 KilA-N domain PSP PF04046.16 EAX70768.1 - 0.081 12.8 0.8 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX70769.1 - 0.022 15.2 0.8 0.03 14.8 0.8 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70769.1 - 0.16 10.9 0.1 0.18 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX70770.1 - 0.0093 15.6 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX70770.1 - 0.19 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX70771.1 - 4.7e-31 108.1 1.7 6.9e-31 107.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX70772.1 - 0.0021 17.7 0.0 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX70772.1 - 0.16 11.8 0.3 1.8 8.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX70774.1 - 4.7e-155 514.1 13.7 5.6e-155 513.8 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX70774.1 - 0.011 16.3 3.2 0.53 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX70774.1 - 0.19 11.5 1.6 0.51 10.2 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX70774.1 - 0.3 11.6 6.2 2.5 8.6 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX70775.1 - 0.083 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX70775.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX70776.1 - 0.028 14.8 0.4 0.038 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX70776.1 - 2.6 8.7 6.3 6.1 7.5 6.3 1.7 1 1 0 1 1 1 0 Homeodomain-like domain DUF4107 PF13389.6 EAX70778.1 - 1.7e-50 171.3 1.7 2e-50 171.1 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX70780.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX70782.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX70783.1 - 2.2e-39 134.6 1.8 2.4e-39 134.5 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX70783.1 - 0.11 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX70785.1 - 4.2e-05 23.6 0.1 5.4e-05 23.2 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70785.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70785.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX70785.1 - 0.0022 18.3 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70785.1 - 0.0039 17.5 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70785.1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX70785.1 - 0.053 13.1 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX70785.1 - 0.093 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX70785.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain ComA PF02679.15 EAX70786.1 - 0.05 13.1 0.4 0.054 13.0 0.4 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX70786.1 - 0.18 11.2 0.3 0.32 10.4 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX70787.1 - 1.2e-138 460.4 13.0 1.3e-138 460.3 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX70787.1 - 0.019 15.2 0.2 1.1 9.6 0.0 3.0 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX70787.1 - 0.1 13.1 1.8 1.1 9.7 0.6 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX70788.1 - 5.7e-34 116.3 0.7 1.2e-33 115.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX70788.1 - 0.028 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Herpes_IE2_3 PF03361.14 EAX70789.1 - 0.009 15.9 1.0 0.3 10.9 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX70789.1 - 0.012 15.9 3.8 0.99 9.7 0.8 2.6 2 0 0 2 2 2 0 PPP5 TPR repeat region Amidase02_C PF12123.8 EAX70790.1 - 0.0035 17.0 0.1 0.0097 15.6 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase RFX_DNA_binding PF02257.15 EAX70791.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX70791.1 - 0.00041 20.8 1.5 0.00067 20.1 1.5 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX70791.1 - 0.041 13.9 0.4 0.075 13.0 0.1 1.5 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX70792.1 - 1.1e-63 213.4 5.9 1.3e-63 213.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX70794.1 - 8.3e-10 38.6 24.2 7.9e-08 32.2 2.4 5.3 4 1 0 4 4 4 2 Phage tail repeat like KinB_sensor PF16767.5 EAX70794.1 - 0.15 12.5 0.7 8.4 6.9 0.2 2.7 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB EpuA PF11772.8 EAX70794.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DNA_pol_B_2 PF03175.13 EAX70796.1 - 1.1e-22 80.6 3.9 1.4e-22 80.3 3.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX70797.1 - 7.4e-111 369.4 7.5 8.5e-111 369.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX70797.1 - 0.047 13.2 0.8 0.065 12.7 0.7 1.3 1 1 0 1 1 1 0 Z1 domain Pox_A32 PF04665.12 EAX70799.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70799.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70799.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70799.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70799.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX70799.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX70799.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX70800.1 - 2.9e-19 69.3 3.9 5.9e-19 68.3 3.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX70800.1 - 0.018 15.1 1.0 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) JMY PF15871.5 EAX70800.1 - 0.033 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Trypan_PARP PF05887.11 EAX70801.1 - 0.028 14.4 8.4 0.032 14.2 8.4 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX70802.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX70803.1 - 4.4e-05 23.0 3.9 7.8e-05 22.2 3.9 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX70803.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX70803.1 - 0.01 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX70803.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX70803.1 - 0.068 13.5 2.1 0.15 12.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) GAGA_bind PF06217.12 EAX70804.1 - 0.015 15.6 5.2 0.017 15.5 5.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3464 PF11947.8 EAX70804.1 - 3.2 7.5 6.8 5.8 6.7 6.8 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ResIII PF04851.15 EAX70805.1 - 1.9e-05 24.7 1.0 3.4e-05 23.9 1.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70805.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX70805.1 - 0.00039 20.7 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX70805.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70805.1 - 0.0067 16.8 0.0 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70805.1 - 0.034 13.6 0.1 0.067 12.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX70805.1 - 0.058 13.1 0.4 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX70805.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX70805.1 - 0.1 12.2 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Vac_Fusion PF02346.16 EAX70805.1 - 0.2 11.3 4.1 2.9 7.6 0.2 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 AAA_30 PF13604.6 EAX70805.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX70805.1 - 0.48 10.9 2.7 0.43 11.0 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX70807.1 - 3.7e-150 498.1 10.9 4.5e-150 497.8 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX70807.1 - 0.019 15.4 1.4 0.083 13.3 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX70807.1 - 0.15 12.5 5.2 1.7 9.2 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX70807.1 - 0.18 11.7 1.7 0.48 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase TPR_MLP1_2 PF07926.12 EAX70808.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX70808.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX70808.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3464 PF11947.8 EAX70809.1 - 0.36 10.6 3.3 0.37 10.5 3.3 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 EAX70809.1 - 1.7 8.7 5.2 1.7 8.7 5.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 EAX70809.1 - 3.8 8.2 5.4 4.2 8.0 5.4 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4108 PF13390.6 EAX70810.1 - 1.1e-58 197.2 6.0 1.2e-58 197.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX70811.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX70811.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase EpuA PF11772.8 EAX70812.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta T5orf172 PF10544.9 EAX70813.1 - 3.4e-06 27.5 0.3 9.1e-06 26.2 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70813.1 - 0.0093 15.8 0.5 0.04 13.8 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX70813.1 - 0.038 13.5 1.3 0.36 10.3 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain HTH_32 PF13565.6 EAX70814.1 - 1.1 10.0 3.6 2.6 8.7 3.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain KIAA1430 PF13879.6 EAX70815.1 - 0.027 15.2 2.9 0.042 14.6 2.9 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DUF2939 PF11159.8 EAX70816.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70816.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX70817.1 - 0.022 15.2 1.8 0.029 14.8 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX70818.1 - 0.00014 21.4 0.4 0.00014 21.4 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX70818.1 - 0.068 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX70819.1 - 5.9e-68 228.9 3.6 7.7e-68 228.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX70820.1 - 3.1e-06 26.8 0.6 3.6e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX70820.1 - 0.036 14.4 0.6 0.036 14.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX70821.1 - 2.2e-07 30.6 0.7 1.7e-06 27.7 0.0 2.2 1 1 1 3 3 3 1 Poxvirus A32 protein TK PF00265.18 EAX70821.1 - 0.081 12.8 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Zot PF05707.12 EAX70821.1 - 0.095 12.3 0.2 2.9 7.5 0.2 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) GatB_Yqey PF02637.18 EAX70821.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 GatB domain DNA_pol_B_2 PF03175.13 EAX70822.1 - 2.7e-10 39.7 8.8 3.4e-10 39.4 3.2 2.4 1 1 1 3 3 3 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX70822.1 - 0.1 12.1 0.7 0.23 11.0 0.7 1.6 1 1 0 1 1 1 0 Isy1-like splicing family Amidase02_C PF12123.8 EAX70824.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX70825.1 - 7.9e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX70825.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX70825.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX70825.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PapD_N PF00345.20 EAX70828.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70828.1 - 0.086 12.8 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TALPID3 PF15324.6 EAX70829.1 - 2.7 5.6 30.4 3.6 5.1 30.4 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Pox_A32 PF04665.12 EAX70830.1 - 1.3e-07 31.4 3.5 1.9e-07 30.8 3.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70830.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70830.1 - 0.067 12.9 0.1 0.21 11.3 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70830.1 - 0.067 12.9 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX70830.1 - 0.32 11.4 3.5 1.4 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF4107 PF13389.6 EAX70832.1 - 2.3e-63 213.2 11.7 1.2e-61 207.7 11.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX70833.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70833.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX70834.1 - 1.3e-15 57.2 1.9 2.4e-15 56.4 1.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70834.1 - 0.015 14.6 0.4 0.022 14.1 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein KilA-N PF04383.13 EAX70835.1 - 1.7e-33 114.8 1.0 2.8e-33 114.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX70835.1 - 0.0057 17.3 0.1 0.017 15.7 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX70837.1 - 5.2e-87 291.3 7.2 5.8e-87 291.1 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX70837.1 - 0.027 14.0 0.2 0.03 13.8 0.2 1.1 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX70837.1 - 0.31 11.7 2.4 1.8 9.2 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Presenilin PF01080.17 EAX70839.1 - 0.15 10.8 0.9 0.16 10.7 0.9 1.0 1 0 0 1 1 1 0 Presenilin Mid2 PF04478.12 EAX70840.1 - 0.00014 21.7 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX70840.1 - 0.00018 21.2 2.0 0.00026 20.7 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX70840.1 - 0.00072 19.7 0.0 0.00082 19.5 0.0 1.1 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX70840.1 - 0.0011 18.9 0.1 0.0015 18.5 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX70840.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX70840.1 - 0.0026 18.0 1.6 0.0037 17.5 1.6 1.4 1 1 0 1 1 1 1 Glycophorin A ECSCR PF15820.5 EAX70840.1 - 0.0053 16.6 0.0 0.006 16.4 0.0 1.1 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DUF3827 PF12877.7 EAX70840.1 - 0.014 13.8 0.0 0.014 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 EAX70840.1 - 0.018 14.4 3.6 0.025 13.9 3.6 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 EAX70840.1 - 0.023 15.6 0.0 0.035 15.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gemini_mov PF01708.16 EAX70840.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.3 1 1 0 1 1 1 0 Geminivirus putative movement protein MMM1 PF10296.9 EAX70840.1 - 0.024 13.7 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 SKG6 PF08693.10 EAX70840.1 - 0.024 14.0 3.9 0.045 13.2 3.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orf78 PF06024.12 EAX70840.1 - 0.028 14.7 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) PTP_tm PF18861.1 EAX70840.1 - 0.037 14.0 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J ODV-E18 PF10717.9 EAX70840.1 - 0.05 13.5 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cortexin PF11057.8 EAX70840.1 - 0.051 13.4 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Cortexin of kidney Otopetrin PF03189.13 EAX70840.1 - 0.061 12.1 0.0 0.061 12.1 0.0 1.0 1 0 0 1 1 1 0 Otopetrin DUF2207 PF09972.9 EAX70840.1 - 0.092 11.5 0.0 0.092 11.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PsbW PF07123.12 EAX70840.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) YukC PF10140.9 EAX70840.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF4448 PF14610.6 EAX70840.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM192 PF14802.6 EAX70840.1 - 0.15 11.1 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family Stevor PF17410.2 EAX70840.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 EAX70840.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF5305 PF17231.2 EAX70840.1 - 0.19 11.1 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF5385 PF17359.2 EAX70840.1 - 0.21 11.1 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 EAX70840.1 - 1.3 8.7 4.2 0.72 9.6 1.6 1.7 1 1 1 2 2 2 0 African swine fever virus J13L protein PapD_N PF00345.20 EAX70842.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX70843.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX70843.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX70844.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70844.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX70844.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX70844.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX70844.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX70844.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Ank_4 PF13637.6 EAX70845.1 - 7.9e-39 131.5 7.1 1.1e-12 48.1 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX70845.1 - 1e-36 123.8 3.1 1.1e-09 38.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAX70845.1 - 3.2e-33 114.2 8.9 7.3e-15 55.3 0.6 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX70845.1 - 1.1e-30 102.2 2.2 2.4e-07 30.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX70845.1 - 1.2e-30 105.2 8.2 2.5e-10 40.4 0.3 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) ThiS-like PF14453.6 EAX70845.1 - 5.3e-05 23.2 3.1 16 5.6 0.0 4.1 1 1 3 4 4 4 4 ThiS-like ubiquitin PH_8 PF15409.6 EAX70845.1 - 0.013 15.8 0.2 30 5.0 0.0 3.6 1 1 3 4 4 4 0 Pleckstrin homology domain Phage_G PF02306.15 EAX70845.1 - 0.014 15.1 0.6 4.6 6.9 0.1 2.3 1 1 1 2 2 2 0 Major spike protein (G protein) Ank_4 PF13637.6 EAX70846.1 - 3.2e-21 75.4 3.0 2.5e-10 40.6 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX70846.1 - 9e-20 70.2 1.0 2.6e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX70846.1 - 6.1e-17 62.0 1.0 2.5e-16 60.0 1.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX70846.1 - 3.2e-16 57.8 0.5 1.5e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX70846.1 - 1.2e-11 44.6 1.2 3.7e-06 27.1 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ThiS-like PF14453.6 EAX70846.1 - 0.0099 15.9 0.6 2.4 8.2 0.1 2.2 1 1 1 2 2 2 2 ThiS-like ubiquitin Ank_4 PF13637.6 EAX70847.1 - 2.5e-22 78.9 1.9 9.4e-10 38.8 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX70847.1 - 5.4e-22 77.2 1.4 4.2e-10 39.6 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX70847.1 - 4.7e-20 71.4 4.9 4.9e-09 36.3 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX70847.1 - 1.8e-18 64.7 0.6 6.6e-07 29.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX70847.1 - 1.8e-17 63.7 1.9 1.2e-07 32.2 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) ThiS-like PF14453.6 EAX70847.1 - 0.013 15.5 2.1 0.98 9.5 0.1 2.7 1 1 2 3 3 3 0 ThiS-like ubiquitin PapD_N PF00345.20 EAX70848.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70848.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX70851.1 - 2.1e-157 521.8 15.4 2.5e-157 521.5 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX70851.1 - 0.11 12.9 0.3 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX70851.1 - 0.8 10.2 6.5 2.1 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX70852.1 - 2.7e-06 27.9 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70852.1 - 0.013 15.3 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX70852.1 - 0.13 11.7 0.7 1.5 8.3 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4378 PF14309.6 EAX70853.1 - 0.017 15.5 0.2 0.066 13.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX70853.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 La domain DUF3839 PF12943.7 EAX70854.1 - 5.7e-119 395.9 12.1 7.2e-119 395.6 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX70854.1 - 0.084 13.3 3.1 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX70854.1 - 0.11 12.3 0.9 0.33 10.8 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX70854.1 - 0.79 10.1 0.1 0.79 10.1 0.1 2.8 4 0 0 4 4 4 0 PRD domain DUF4108 PF13390.6 EAX70855.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX70856.1 - 4.1e-05 24.0 2.1 0.00025 21.5 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX70856.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) MULE PF10551.9 EAX70857.1 - 5.9e-09 36.2 0.7 5.9e-09 36.2 0.7 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX70857.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Trypan_PARP PF05887.11 EAX70858.1 - 0.05 13.6 9.3 0.065 13.2 9.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VirE PF05272.11 EAX70861.1 - 2e-05 24.4 0.1 3.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX70861.1 - 8.3e-05 23.0 2.4 0.00052 20.5 2.4 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX70861.1 - 0.045 14.1 0.3 0.15 12.4 0.1 2.0 1 1 1 2 2 2 0 RNA helicase Trypan_PARP PF05887.11 EAX70863.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX70863.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Apolipoprotein PF01442.18 EAX70864.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain KilA-N PF04383.13 EAX70866.1 - 6.7e-18 64.6 0.1 8.5e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX70866.1 - 0.023 14.6 0.0 0.054 13.5 0.0 1.6 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Trypan_PARP PF05887.11 EAX70867.1 - 0.056 13.4 11.0 0.068 13.2 11.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX70867.1 - 5.3 7.5 7.7 6.8 7.1 7.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX70868.1 - 0.036 13.1 0.1 0.036 13.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX70868.1 - 0.044 14.2 0.4 0.053 14.0 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DNA_pol_B_2 PF03175.13 EAX70869.1 - 2.2e-29 102.7 6.3 3.9e-29 101.8 6.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ResIII PF04851.15 EAX70870.1 - 6.2e-05 23.1 2.7 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX70870.1 - 6.4e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX70870.1 - 0.0004 20.2 0.0 0.00054 19.8 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70870.1 - 0.0013 18.6 1.4 0.0042 16.9 1.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70870.1 - 0.0073 16.7 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70870.1 - 0.047 13.2 0.1 0.069 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX70870.1 - 0.076 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX70870.1 - 0.094 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70870.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX70870.1 - 0.23 11.2 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX70870.1 - 0.66 10.3 4.4 17 5.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX70872.1 - 0.048 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SH3BGR PF04908.15 EAX70873.1 - 0.33 11.1 3.5 0.43 10.8 3.3 1.4 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2897 PF11446.8 EAX70873.1 - 0.84 9.6 3.2 1.5 8.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70874.1 - 4.5e-65 217.9 6.3 5.1e-65 217.8 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Noggin PF05806.12 EAX70875.1 - 0.25 11.2 1.8 0.37 10.7 1.8 1.1 1 0 0 1 1 1 0 Noggin T5orf172 PF10544.9 EAX70877.1 - 1e-06 29.2 0.1 2.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70877.1 - 0.062 13.2 0.1 0.51 10.2 0.0 2.3 2 1 0 2 2 2 0 KilA-N domain Trypan_PARP PF05887.11 EAX70878.1 - 0.074 13.0 9.2 0.11 12.4 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX70878.1 - 2.1 8.8 5.9 3 8.3 5.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapD_N PF00345.20 EAX70879.1 - 0.046 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70879.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX70883.1 - 1.6e-10 40.5 2.7 4.4e-10 39.0 2.7 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70883.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX70883.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX70886.1 - 5.6e-08 32.5 1.2 9.2e-08 31.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX70888.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX70889.1 - 0.081 13.4 0.4 0.17 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX70890.1 - 6.8e-05 22.4 3.4 7.1e-05 22.4 2.4 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Y_phosphatase2 PF03162.13 EAX70890.1 - 0.011 15.3 0.3 0.025 14.1 0.3 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX70890.1 - 0.017 15.1 0.9 0.041 13.9 0.2 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX70890.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PSP PF04046.16 EAX70891.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70892.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Chal_sti_synt_N PF00195.19 EAX70894.1 - 0.23 10.9 0.4 0.4 10.1 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain CooT PF10133.9 EAX70896.1 - 0.042 14.1 0.2 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT Pox_D5 PF03288.16 EAX70897.1 - 3.2e-05 24.3 2.8 0.00016 22.1 2.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70897.1 - 0.059 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70897.1 - 0.082 12.9 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX70899.1 - 2.9e-52 174.6 37.6 1.7e-34 117.7 16.8 4.3 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX70899.1 - 0.08 12.7 1.0 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX70899.1 - 1.3 9.4 5.3 17 5.8 0.2 3.8 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF4264 PF14084.6 EAX70900.1 - 0.024 14.2 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Pox_A32 PF04665.12 EAX70901.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF5446 PF17522.2 EAX70902.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3417 PF11897.8 EAX70903.1 - 0.054 14.0 0.6 0.092 13.2 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) ResIII PF04851.15 EAX70904.1 - 5.1e-05 23.3 2.2 9.7e-05 22.4 2.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70904.1 - 0.00034 20.4 0.0 0.00045 20.0 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX70904.1 - 0.00039 20.7 0.0 0.00063 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX70904.1 - 0.00076 19.3 0.9 0.0025 17.7 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX70904.1 - 0.007 16.7 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70904.1 - 0.035 13.6 0.1 0.056 12.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX70904.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FliJ PF02050.16 EAX70907.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX70908.1 - 7e-49 166.1 1.2 9.5e-49 165.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX70909.1 - 0.074 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70910.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX70911.1 - 0.014 15.9 0.6 0.026 15.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70911.1 - 0.87 9.7 4.1 17 5.5 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF1493 PF07377.12 EAX70912.1 - 0.027 15.0 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX70912.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4107 PF13389.6 EAX70914.1 - 4e-34 118.1 2.2 5.8e-34 117.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX70916.1 - 1.1e-153 509.6 13.0 1.3e-153 509.3 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70916.1 - 0.2 11.5 1.8 0.47 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX70916.1 - 0.32 11.5 7.9 1.8 9.0 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX70916.1 - 0.48 10.7 5.5 1.9 8.8 0.1 3.3 2 2 0 2 2 2 0 Rx N-terminal domain DUF5398 PF17376.2 EAX70916.1 - 0.64 10.7 3.3 0.76 10.4 0.1 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5398) PapD_N PF00345.20 EAX70918.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70918.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX70920.1 - 0.013 15.9 0.5 0.015 15.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70920.1 - 1.9 7.4 3.6 1.9 7.4 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX70920.1 - 2.1 8.4 7.5 2.2 8.3 7.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 LRV PF01816.17 EAX70921.1 - 0.061 13.7 1.1 54 4.5 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat variant Ctr PF04145.15 EAX70921.1 - 4.1 8.0 5.0 97 3.6 4.9 2.6 1 1 0 1 1 1 0 Ctr copper transporter family SPX PF03105.19 EAX70921.1 - 7.9 6.3 17.7 4.9 7.0 3.3 2.0 1 1 1 2 2 2 0 SPX domain T5orf172 PF10544.9 EAX70923.1 - 4.4e-06 27.2 0.1 8.7e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4378 PF14309.6 EAX70924.1 - 0.014 15.8 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) DUF3839 PF12943.7 EAX70925.1 - 5.9e-139 461.4 10.0 6.8e-139 461.2 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX70925.1 - 0.086 13.1 3.5 0.8 10.0 0.0 3.0 2 1 0 2 2 2 0 Rx N-terminal domain DUF5398 PF17376.2 EAX70925.1 - 0.16 12.6 1.5 0.61 10.8 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX70925.1 - 0.24 11.9 1.9 2.1 8.8 0.6 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX70926.1 - 8.7e-96 321.7 6.9 8.7e-96 321.7 6.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX70926.1 - 0.12 10.9 3.6 0.15 10.7 3.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A EMC3_TMCO1 PF01956.16 EAX70926.1 - 3.6 7.3 5.7 0.88 9.3 1.1 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DDE_Tnp_4 PF13359.6 EAX70928.1 - 2.7e-29 101.9 0.0 4.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX70928.1 - 1.1e-08 35.0 0.1 5.3e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain Chordopox_G3 PF06129.12 EAX70928.1 - 0.15 12.8 0.7 0.53 11.0 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus G3 protein PapD_N PF00345.20 EAX70930.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX70930.1 - 0.065 13.2 0.7 0.092 12.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF4106 PF13388.6 EAX70931.1 - 5.5e-189 628.7 58.2 3.8e-125 418.4 19.3 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX70931.1 - 0.17 11.7 0.1 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) SOG2 PF10428.9 EAX70931.1 - 4.1 6.5 16.1 5.7 6.0 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EAX70931.1 - 5.3 5.6 15.8 8.6 4.9 15.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2897 PF11446.8 EAX70932.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX70933.1 - 8.7e-05 22.6 3.2 0.00016 21.7 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX70933.1 - 8.8e-05 22.8 0.0 0.00045 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX70933.1 - 0.0004 20.2 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70933.1 - 0.001 18.9 1.2 0.0035 17.2 1.2 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX70933.1 - 0.0018 18.0 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX70933.1 - 0.0093 16.3 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX70933.1 - 0.048 13.1 0.1 0.076 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX70933.1 - 0.051 13.3 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX70933.1 - 0.086 13.3 0.1 0.38 11.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX70933.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX70933.1 - 0.17 12.2 5.0 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX70935.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70936.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP IKKbetaNEMObind PF12179.8 EAX70937.1 - 0.11 12.5 0.1 0.4 10.7 0.1 1.9 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DNA_pol_B_2 PF03175.13 EAX70938.1 - 5.2e-29 101.4 6.8 9.3e-29 100.6 6.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX70939.1 - 1.2e-41 141.1 0.0 1.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX70940.1 - 1.2e-06 28.9 0.3 2.5e-06 28.0 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX70941.1 - 1e-18 67.2 0.1 1.3e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX70941.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PTR PF12789.7 EAX70942.1 - 4e-48 161.3 30.9 5.9e-32 109.5 14.4 3.9 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX70942.1 - 0.025 14.3 1.0 0.05 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX70942.1 - 6.9 7.4 7.1 14 6.4 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DNA_pol_B_2 PF03175.13 EAX70943.1 - 7.3e-12 44.9 0.7 2.8e-10 39.7 0.2 1.9 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70943.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX70944.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX70944.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX70944.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX70944.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DDR PF08841.10 EAX70945.1 - 0.064 12.2 0.1 0.065 12.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX70945.1 - 0.079 13.4 1.5 0.12 12.9 1.5 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain HCBP_related PF06594.11 EAX70946.1 - 0.01 15.7 0.1 1.9e+02 2.1 0.0 4.6 5 0 0 5 5 5 0 Haemolysin-type calcium binding protein related domain TcpS PF17456.2 EAX70946.1 - 0.034 14.2 0.6 5.8 7.0 0.1 2.2 1 1 0 2 2 2 0 Toxin-coregulated pilus protein S Chordopox_A30L PF06015.12 EAX70946.1 - 4.3 7.2 12.4 18 5.3 1.1 3.4 1 1 4 5 5 5 0 Chordopoxvirus A30L protein IstB_IS21 PF01695.17 EAX70947.1 - 2.7e-05 24.0 0.2 0.31 10.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX70947.1 - 3e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX70947.1 - 3.9e-05 23.2 1.8 3.9e-05 23.2 1.8 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX70947.1 - 0.00025 21.1 4.1 0.00041 20.4 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX70947.1 - 0.00055 19.7 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX70947.1 - 0.0014 18.5 0.6 0.0031 17.3 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX70947.1 - 0.0054 16.4 2.2 0.014 15.1 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX70947.1 - 0.014 15.8 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX70947.1 - 0.065 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX70947.1 - 0.069 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX70947.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX70947.1 - 0.099 13.1 0.6 0.72 10.3 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX70947.1 - 0.43 10.9 4.5 8.2 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX70947.1 - 4.4 8.0 11.0 0.29 11.8 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF2939 PF11159.8 EAX70948.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX70948.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX70948.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX70948.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX70949.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX70950.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX70953.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX70953.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX70954.1 - 8.9e-08 32.0 0.2 8.9e-08 32.0 0.2 1.7 2 1 0 2 2 2 1 KilA-N domain NTS PF15447.6 EAX70954.1 - 0.55 10.8 4.3 3.7 8.1 1.7 2.4 1 1 1 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX70955.1 - 5.1e-103 343.7 5.9 6.5e-103 343.4 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX70956.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX70957.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX70958.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX70958.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX70959.1 - 0.092 12.7 7.6 0.14 12.1 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX70960.1 - 3.1e-155 514.7 12.1 3.9e-155 514.4 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70960.1 - 0.15 12.0 0.6 0.34 10.8 0.2 1.7 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX70960.1 - 0.42 10.9 4.2 1.7 9.0 0.1 3.3 2 2 1 3 3 3 0 Rx N-terminal domain PadR PF03551.14 EAX70962.1 - 0.078 13.0 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF659 PF04937.15 EAX70963.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) DUF4107 PF13389.6 EAX70964.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Imm70 PF15601.6 EAX70965.1 - 0.0036 16.8 5.9 2.6 7.6 0.1 3.1 1 1 2 3 3 3 3 Immunity protein 70 DUF3447 PF11929.8 EAX70965.1 - 7.2 6.7 17.9 10 6.2 5.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DNA_pol_B_2 PF03175.13 EAX70966.1 - 2.5e-17 62.9 4.6 4.5e-17 62.1 4.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX70966.1 - 0.0097 15.2 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX70966.1 - 0.028 14.5 1.6 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DNA_pol_B_2 PF03175.13 EAX70967.1 - 4.1e-08 32.5 0.9 7.6e-08 31.6 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX70967.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 PSP PF04046.16 EAX70968.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX70969.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX70971.1 - 4.9e-07 29.6 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX70971.1 - 0.22 10.9 0.2 0.28 10.6 0.2 1.3 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain LBR_tudor PF09465.10 EAX70972.1 - 0.00035 20.3 0.1 0.00066 19.4 0.1 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX70972.1 - 0.033 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor DUF3839 PF12943.7 EAX70973.1 - 1e-156 519.5 13.6 1.3e-156 519.2 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX70973.1 - 0.17 11.7 1.2 0.59 10.0 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX70973.1 - 0.19 12.3 5.6 0.22 12.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX70973.1 - 0.31 11.5 4.6 4.8 7.7 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX70973.1 - 5.7 7.3 7.1 14 6.0 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal DUF4107 PF13389.6 EAX70974.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX70974.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX70975.1 - 2.7e-28 99.1 7.6 4.2e-28 98.4 7.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX70975.1 - 0.053 13.8 0.4 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX70975.1 - 0.075 13.5 0.7 0.41 11.1 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB AlphaC_N PF08829.10 EAX70976.1 - 0.066 13.2 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX70977.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX70977.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX70977.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein BRO1 PF03097.18 EAX70978.1 - 0.04 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX70978.1 - 0.16 12.2 4.8 1.8 8.9 0.3 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX70978.1 - 0.21 12.1 1.8 3.6 8.2 1.9 2.3 1 1 1 2 2 2 0 YmaF family PTR PF12789.7 EAX70979.1 - 7.7e-10 38.7 6.7 1.2e-08 34.9 1.4 4.9 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX70979.1 - 0.37 10.3 14.4 0.85 9.2 2.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX70979.1 - 0.45 10.6 7.2 0.3 11.2 2.6 2.3 1 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) ATR13 PF16829.5 EAX70979.1 - 1.9 8.9 6.0 2.7 8.4 3.1 2.4 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector CppA_C PF14507.6 EAX70979.1 - 2.7 8.8 5.3 1 10.1 0.8 2.4 2 1 1 3 3 3 0 CppA C-terminal ATP-synt_E PF05680.12 EAX70980.1 - 2.7 8.4 9.3 6.5 7.2 9.3 1.6 1 0 0 1 1 1 0 ATP synthase E chain Pox_A32 PF04665.12 EAX70982.1 - 2.7e-06 27.1 0.2 3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX70982.1 - 0.095 13.0 1.1 0.11 12.8 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Amidase02_C PF12123.8 EAX70984.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX70986.1 - 8.3e-35 118.7 19.6 7.6e-34 115.6 15.4 4.6 4 2 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX70986.1 - 0.011 15.5 0.1 0.036 13.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2897 PF11446.8 EAX70987.1 - 0.15 12.0 2.2 0.18 11.7 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX70988.1 - 2.9e-61 205.6 8.2 3.3e-61 205.4 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX70989.1 - 5.4e-49 164.1 32.0 1.1e-32 111.9 15.7 4.1 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX70989.1 - 0.028 14.1 0.9 0.053 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX70989.1 - 1.4 9.3 5.1 26 5.3 0.2 3.6 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain Pox_A32 PF04665.12 EAX70990.1 - 1.5e-06 27.8 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX70992.1 - 7.4e-23 81.1 8.5 8e-22 77.7 8.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX70992.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_D5 PF03288.16 EAX70993.1 - 2.2e-05 24.8 3.3 0.00017 22.0 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX70993.1 - 0.069 13.8 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX70993.1 - 0.089 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX70994.1 - 1.2e-41 141.1 0.1 2.2e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain DUF2939 PF11159.8 EAX70995.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX70995.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX70995.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX70996.1 - 0.0099 15.9 0.5 0.012 15.6 0.5 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX70996.1 - 0.43 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX70997.1 - 3.9e-10 39.2 2.3 1.6e-09 37.2 2.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70997.1 - 0.08 12.9 0.0 0.7 9.9 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX70997.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX70997.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF4116 PF13475.6 EAX70998.1 - 0.01 15.6 0.1 0.054 13.2 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX70998.1 - 0.044 12.8 1.0 0.063 12.3 0.7 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX70998.1 - 0.057 13.9 5.6 0.075 13.5 0.1 3.1 1 1 2 4 4 4 0 Protein of unknown function (DUF3417) PTR PF12789.7 EAX70998.1 - 0.34 11.0 0.1 0.34 11.0 0.1 4.4 2 1 2 4 4 4 0 Phage tail repeat like DUF445 PF04286.12 EAX70998.1 - 0.64 9.8 6.9 1.1 9.0 6.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) TbpB_A PF17484.2 EAX70998.1 - 3.4 8.4 7.3 9.1 7.0 7.3 1.8 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B DNA_pol_B_2 PF03175.13 EAX70999.1 - 9.7e-25 87.4 11.1 3.5e-24 85.5 11.1 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX70999.1 - 0.08 12.9 0.0 0.93 9.5 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX70999.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX71000.1 - 2.4e-22 79.5 4.2 3.3e-22 79.0 4.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71000.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PapD_N PF00345.20 EAX71001.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71001.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX71003.1 - 2.7e-126 419.9 8.2 3.1e-126 419.7 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX71003.1 - 0.16 12.9 0.7 5.2 8.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) KELK PF15796.5 EAX71003.1 - 0.23 12.0 1.6 1.1 9.7 0.7 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAS_N PF17828.1 EAX71005.1 - 0.006 16.6 0.2 0.008 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71006.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71006.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX71007.1 - 6.6e-17 61.5 3.8 1.3e-16 60.6 3.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX71007.1 - 0.038 13.3 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DNA_pol_B_2 PF03175.13 EAX71009.1 - 6.2e-10 38.5 2.3 3.1e-09 36.2 2.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX71009.1 - 0.12 12.4 0.0 0.95 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX71009.1 - 0.12 11.0 2.2 5 5.7 2.0 3.0 2 1 0 2 2 2 0 DNA polymerase family B DDE_1 PF03184.19 EAX71010.1 - 9.6e-10 38.4 0.5 1.7e-09 37.6 0.1 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3839 PF12943.7 EAX71013.1 - 1.4e-153 509.3 11.9 1.8e-153 508.9 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX71013.1 - 0.41 11.0 3.7 15 6.0 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX71013.1 - 0.9 10.0 6.3 1.8 9.1 0.1 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SH3BGR PF04908.15 EAX71014.1 - 0.03 14.5 0.7 0.036 14.2 0.7 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF3417 PF11897.8 EAX71014.1 - 0.089 13.3 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX71014.1 - 0.37 10.7 2.7 0.63 10.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71015.1 - 2.7e-57 192.7 4.4 3e-57 192.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71016.1 - 6.5e-06 26.6 2.6 2.8e-05 24.5 2.6 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71016.1 - 0.013 16.1 0.1 0.024 15.2 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71016.1 - 0.038 14.0 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX71017.1 - 1.3e-17 63.6 2.8 1.3e-17 63.6 2.8 3.2 4 1 0 4 4 4 1 Phage tail repeat like DUF240 PF03086.14 EAX71017.1 - 0.091 12.7 2.5 1.5 8.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Pox_A32 PF04665.12 EAX71019.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX71021.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71021.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF1043 PF06295.12 EAX71023.1 - 0.024 14.6 0.1 0.032 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CBM_15 PF03426.14 EAX71023.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF2939 PF11159.8 EAX71024.1 - 0.015 15.7 0.4 0.017 15.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Amidase02_C PF12123.8 EAX71025.1 - 0.03 14.0 0.1 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX71026.1 - 6.3e-35 119.4 0.4 1.5e-34 118.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain AAA_22 PF13401.6 EAX71027.1 - 2.9e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71027.1 - 3.5e-05 23.6 0.3 0.38 10.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX71027.1 - 4.3e-05 23.1 2.0 4.3e-05 23.1 2.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein ResIII PF04851.15 EAX71027.1 - 0.00039 20.5 4.7 0.00072 19.6 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71027.1 - 0.00056 19.7 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71027.1 - 0.0018 18.1 1.3 0.003 17.4 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71027.1 - 0.0045 16.6 2.4 0.014 15.1 0.2 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71027.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX71027.1 - 0.063 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 TPK_catalytic PF04263.16 EAX71027.1 - 0.065 13.3 0.9 1.1 9.3 0.9 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX71027.1 - 0.068 12.7 0.0 0.23 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX71027.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX71027.1 - 0.097 13.1 0.5 0.73 10.3 0.1 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX71027.1 - 0.33 11.2 4.5 6.4 7.1 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX71027.1 - 4.1 8.1 11.8 0.25 12.0 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX71029.1 - 8.4e-105 349.6 7.6 9.6e-105 349.4 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX71030.1 - 4.3e-64 214.7 6.3 4.8e-64 214.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PcfK PF14058.6 EAX71031.1 - 0.046 14.0 6.3 0.07 13.4 6.3 1.4 1 1 0 1 1 1 0 PcfK-like protein zf-C5HC2 PF02928.16 EAX71032.1 - 0.12 12.8 3.2 0.19 12.1 3.2 1.3 1 0 0 1 1 1 0 C5HC2 zinc finger DDE_1 PF03184.19 EAX71033.1 - 2.9e-11 43.3 0.0 3.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4107 PF13389.6 EAX71034.1 - 1.1e-14 54.9 0.8 1.2e-14 54.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) HTH_44 PF14641.6 EAX71036.1 - 0.059 13.8 0.1 0.069 13.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 PTR PF12789.7 EAX71037.1 - 1.5e-23 82.6 8.8 1.5e-23 82.6 8.8 3.8 2 2 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX71037.1 - 0.027 14.2 0.3 0.077 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX71037.1 - 0.29 11.1 7.5 1.1 9.2 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DNA_pol_B_2 PF03175.13 EAX71038.1 - 1.3e-22 80.3 10.5 9.4e-22 77.5 10.5 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX71039.1 - 0.063 13.7 0.4 0.085 13.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71039.1 - 1.2 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX71039.1 - 1.5 8.8 5.5 1.6 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX71042.1 - 2.9e-152 505.0 10.7 3.3e-152 504.8 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX71042.1 - 0.026 15.0 1.0 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX71042.1 - 0.032 14.5 0.4 8.9 6.7 0.1 3.1 2 1 1 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX71042.1 - 0.38 11.2 5.9 2.4 8.7 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX71043.1 - 0.054 13.4 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71043.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX71045.1 - 2.1e-154 512.0 12.4 2.6e-154 511.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX71045.1 - 0.49 11.0 3.2 4.8 7.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX71045.1 - 1.8 9.1 5.9 2.5 8.6 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX71046.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71046.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX71047.1 - 0.017 15.2 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PadR PF03551.14 EAX71049.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PSP PF04046.16 EAX71050.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX71051.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PapD_N PF00345.20 EAX71054.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX71054.1 - 0.13 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4108 PF13390.6 EAX71055.1 - 1.1e-62 210.2 5.8 1.2e-62 210.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX71056.1 - 0.14 12.0 3.0 0.28 11.1 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) FAS_N PF17828.1 EAX71057.1 - 0.0075 16.3 0.2 0.01 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71058.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71058.1 - 1.6 8.8 5.6 1.7 8.7 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Trypan_PARP PF05887.11 EAX71059.1 - 0.077 13.0 10.9 0.12 12.3 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX71060.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX71060.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX71061.1 - 1.3e-55 187.3 6.6 1.4e-55 187.2 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX71064.1 - 5.8e-146 484.3 10.4 6.7e-146 484.1 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX71064.1 - 0.13 12.9 0.8 0.68 10.6 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX71066.1 - 5.1e-117 389.6 7.6 5.8e-117 389.4 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71066.1 - 0.5 10.9 3.0 1.1 9.7 0.9 2.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_22 PF13401.6 EAX71067.1 - 6.2e-05 23.3 0.1 0.00042 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71067.1 - 7.3e-05 22.8 2.6 0.00013 22.0 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71067.1 - 0.00046 20.0 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71067.1 - 0.0011 18.8 1.0 0.0037 17.1 1.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71067.1 - 0.0018 18.1 0.3 0.18 11.5 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX71067.1 - 0.0088 16.4 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71067.1 - 0.052 13.0 0.1 0.078 12.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX71067.1 - 0.053 13.9 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX71067.1 - 0.065 13.0 0.1 0.098 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX71067.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX71067.1 - 0.35 11.2 5.1 5.7 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX71067.1 - 0.84 10.1 4.2 0.41 11.1 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF2939 PF11159.8 EAX71069.1 - 0.016 15.6 0.4 0.021 15.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX71070.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX71071.1 - 0.47 10.4 3.8 0.26 11.2 0.6 2.2 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX71072.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX71073.1 - 6.1e-07 29.1 3.0 6.1e-07 29.1 3.0 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71073.1 - 2.4e-05 24.7 0.2 0.00017 21.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71073.1 - 0.0001 22.3 2.0 0.00024 21.2 2.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71073.1 - 0.00051 19.8 0.0 0.00093 19.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EAX71073.1 - 0.00079 19.2 0.1 0.43 10.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_11 PF13086.6 EAX71073.1 - 0.0011 18.9 0.7 0.0019 18.0 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71073.1 - 0.0018 18.0 0.5 0.011 15.4 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71073.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX71073.1 - 0.062 12.8 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX71073.1 - 0.067 12.8 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71073.1 - 0.075 13.5 0.1 0.63 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71073.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2666 PF10869.8 EAX71073.1 - 0.85 9.8 8.7 7.3 6.8 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF1493 PF07377.12 EAX71074.1 - 0.05 14.1 0.8 0.092 13.2 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX71074.1 - 0.27 11.3 4.0 5 7.2 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DNA_pol_B_2 PF03175.13 EAX71075.1 - 1.3e-10 40.8 3.7 1.1e-09 37.7 3.1 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71075.1 - 0.093 13.0 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX71076.1 - 4.9e-42 143.8 0.4 5.6e-42 143.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX71077.1 - 9.5e-07 28.5 2.5 9.5e-07 28.5 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71077.1 - 3.1e-05 24.3 0.2 0.00026 21.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71077.1 - 4e-05 23.4 0.3 0.37 10.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71077.1 - 0.00013 22.0 3.1 0.00032 20.7 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71077.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71077.1 - 0.0015 18.4 0.7 0.0031 17.4 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71077.1 - 0.0021 17.7 0.5 0.014 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71077.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX71077.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX71077.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX71077.1 - 0.094 13.1 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX71077.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX71077.1 - 8.6 6.6 13.5 3.4 7.9 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX71078.1 - 7.5e-79 264.6 10.2 9.7e-79 264.2 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71078.1 - 0.19 11.6 1.2 0.81 9.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX71080.1 - 2.1e-07 31.4 0.3 4.3e-07 30.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX71080.1 - 0.15 12.8 0.3 0.4 11.4 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX71081.1 - 9.5e-07 28.7 0.3 1.9e-06 27.7 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX71082.1 - 7.5e-23 80.4 30.2 3.4e-22 78.2 8.4 4.7 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX71082.1 - 0.23 11.0 14.3 72 2.9 14.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX71084.1 - 2e-64 215.8 6.1 2.2e-64 215.7 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX71085.1 - 2.3e-183 610.2 30.6 8.6e-183 608.3 30.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX71085.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Dicty_REP PF05086.12 EAX71085.1 - 1.1 7.1 6.1 1.6 6.6 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sof1 PF04158.14 EAX71085.1 - 1.9 8.8 5.8 8.1 6.8 0.3 2.7 2 0 0 2 2 2 0 Sof1-like domain Ndc1_Nup PF09531.10 EAX71085.1 - 3.6 6.2 7.9 5.6 5.5 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPATA3 PF15662.5 EAX71085.1 - 6.6 7.3 14.7 14 6.3 14.7 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF2939 PF11159.8 EAX71086.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71086.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX71087.1 - 6.1e-148 490.8 14.8 7.5e-148 490.5 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX71087.1 - 0.16 12.5 5.0 1.5 9.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX71087.1 - 2.4 8.7 7.6 3 8.4 0.6 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX71088.1 - 1.7e-22 79.9 4.1 2.2e-22 79.6 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71088.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX71089.1 - 5.5e-26 91.5 8.5 9.2e-26 90.7 8.5 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAX71090.1 - 2.2e-07 31.4 0.3 4.1e-07 30.5 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain EF-hand_10 PF14788.6 EAX71092.1 - 0.0024 17.7 0.1 0.0075 16.1 0.1 1.9 1 0 0 1 1 1 1 EF hand EVC2_like PF12297.8 EAX71092.1 - 0.0056 15.4 0.2 0.01 14.6 0.2 1.4 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein YABBY PF04690.13 EAX71092.1 - 0.012 16.2 0.6 0.024 15.2 0.6 1.4 1 0 0 1 1 1 0 YABBY protein DUF257 PF03192.13 EAX71093.1 - 0.0013 18.5 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX71093.1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3839 PF12943.7 EAX71095.1 - 2e-51 174.8 2.6 2.3e-51 174.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX71095.1 - 0.0032 17.2 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX71095.1 - 0.11 12.8 2.2 0.25 11.7 2.2 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF1493 PF07377.12 EAX71097.1 - 0.023 15.2 0.8 0.045 14.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Peptidase_C74 PF12387.8 EAX71098.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Pox_A32 PF04665.12 EAX71099.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX71101.1 - 1.3e-60 203.5 8.6 1.5e-60 203.3 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71101.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide T5orf172 PF10544.9 EAX71103.1 - 5.1e-05 23.7 0.1 0.00011 22.6 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Egg_lysin PF01303.17 EAX71103.1 - 0.0016 18.7 0.4 0.0049 17.1 0.1 1.9 1 1 1 2 2 2 1 Egg lysin (Sperm-lysin) KilA-N PF04383.13 EAX71103.1 - 0.016 15.1 1.5 0.096 12.5 0.3 2.5 2 1 0 2 2 2 0 KilA-N domain T5orf172 PF10544.9 EAX71105.1 - 7.6e-07 29.6 0.5 2.2e-06 28.1 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX71105.1 - 0.004 16.7 0.5 0.048 13.2 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain Trypan_PARP PF05887.11 EAX71108.1 - 0.05 13.6 8.2 0.059 13.3 8.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX71108.1 - 3.2 8.2 4.9 3.5 8.1 4.9 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX71109.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX71112.1 - 1.1e-41 141.1 1.1 1.7e-41 140.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX71112.1 - 0.031 14.5 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX71113.1 - 1.5e-97 325.8 7.7 1.7e-97 325.7 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DBB PF14545.6 EAX71113.1 - 0.044 13.7 0.7 0.064 13.2 0.6 1.3 1 1 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Pox_D5 PF03288.16 EAX71115.1 - 3.5e-05 24.2 1.9 0.00016 22.1 1.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71115.1 - 0.022 13.8 0.9 0.032 13.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3198 PF11433.8 EAX71115.1 - 0.091 12.7 0.0 9.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) DUF4108 PF13390.6 EAX71116.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX71117.1 - 2.1e-07 30.6 2.1 3.2e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71117.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71117.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71117.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71117.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX71117.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX71117.1 - 0.55 10.4 8.3 5.8 7.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Ank_2 PF12796.7 EAX71118.1 - 1.2e-77 256.5 3.2 1.1e-17 64.3 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX71118.1 - 4.3e-54 180.2 0.1 5.4e-12 46.0 0.0 5.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX71118.1 - 2.9e-49 164.5 3.2 6e-11 42.4 0.0 6.8 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX71118.1 - 1.5e-47 158.0 0.2 2e-06 28.0 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX71118.1 - 1.2e-38 126.7 0.0 5.3e-05 23.3 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat FapA PF03961.13 EAX71118.1 - 0.0013 17.4 6.4 0.0029 16.3 6.4 1.6 1 0 0 1 1 1 1 Flagellar Assembly Protein A Spc29 PF17082.5 EAX71118.1 - 0.0019 18.1 4.4 0.0028 17.5 4.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 APG6_N PF17675.1 EAX71118.1 - 0.0022 18.5 10.7 0.0038 17.7 10.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 EAX71118.1 - 0.0041 16.0 7.4 0.0057 15.6 7.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Wtap PF17098.5 EAX71118.1 - 0.0054 16.7 5.8 0.0094 15.9 5.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family DUF2203 PF09969.9 EAX71118.1 - 0.0093 16.7 1.8 0.018 15.8 1.8 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) ATG16 PF08614.11 EAX71118.1 - 0.011 15.9 6.8 0.017 15.3 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GBP_C PF02841.14 EAX71118.1 - 0.018 14.4 7.0 0.026 13.9 7.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Fmp27_WPPW PF10359.9 EAX71118.1 - 0.021 13.7 5.1 0.028 13.3 5.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FliJ PF02050.16 EAX71118.1 - 0.021 15.0 5.5 0.055 13.7 5.5 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein Muted PF14942.6 EAX71118.1 - 0.031 14.6 8.5 0.054 13.8 8.5 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Het-C PF07217.11 EAX71118.1 - 0.035 12.7 3.5 0.045 12.3 3.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ABC_tran_CTD PF16326.5 EAX71118.1 - 0.036 14.3 6.9 0.078 13.2 6.9 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF812 PF05667.11 EAX71118.1 - 0.044 12.7 8.9 0.06 12.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FBD PF08387.10 EAX71118.1 - 0.05 13.5 0.0 37 4.3 0.0 4.3 4 1 1 5 5 5 0 FBD OmpH PF03938.14 EAX71118.1 - 0.063 13.6 8.2 0.11 12.9 8.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 EAX71118.1 - 0.067 12.7 8.9 0.095 12.1 8.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 WXG100 PF06013.12 EAX71118.1 - 0.098 12.9 2.9 0.23 11.7 2.9 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG COG2 PF06148.11 EAX71118.1 - 0.13 12.3 5.9 0.11 12.6 3.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_32 PF13654.6 EAX71118.1 - 0.16 10.7 6.2 0.23 10.2 6.2 1.1 1 0 0 1 1 1 0 AAA domain RapA_C PF12137.8 EAX71118.1 - 0.17 10.8 4.4 0.26 10.3 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF1664 PF07889.12 EAX71118.1 - 0.18 11.9 4.5 0.32 11.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EAX71118.1 - 0.21 10.8 5.1 0.3 10.3 5.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein YlqD PF11068.8 EAX71118.1 - 0.25 11.7 7.8 0.42 11.0 7.8 1.3 1 0 0 1 1 1 0 YlqD protein TMF_TATA_bd PF12325.8 EAX71118.1 - 0.26 11.5 11.0 0.29 11.4 8.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ACCA PF03255.14 EAX71118.1 - 0.27 11.1 3.7 0.54 10.1 3.7 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Allexi_40kDa PF05549.11 EAX71118.1 - 0.29 10.6 3.4 0.41 10.1 3.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 EAX71118.1 - 0.33 8.8 5.0 0.39 8.6 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 5_nucleotid PF05761.14 EAX71118.1 - 0.38 9.6 4.4 0.54 9.1 4.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family GIT1_C PF12205.8 EAX71118.1 - 0.44 10.7 5.0 0.65 10.1 4.5 1.5 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4407 PF14362.6 EAX71118.1 - 0.51 9.6 2.8 0.73 9.1 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 EAX71118.1 - 0.52 10.1 5.4 0.95 9.2 5.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.8 EAX71118.1 - 0.63 9.3 6.0 0.93 8.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2730 PF10805.8 EAX71118.1 - 0.67 10.1 4.2 1.2 9.3 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Spc24 PF08286.11 EAX71118.1 - 0.68 10.2 13.7 0.46 10.8 8.8 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 EAX71118.1 - 0.83 9.8 13.6 0.25 11.4 8.0 2.3 1 1 1 2 2 2 0 Swi5 PCRF PF03462.18 EAX71118.1 - 0.98 9.2 5.7 1.6 8.6 5.7 1.3 1 0 0 1 1 1 0 PCRF domain Occludin_ELL PF07303.13 EAX71118.1 - 0.98 10.2 7.0 1.3 9.8 2.8 2.3 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 EAX71118.1 - 1.1 8.3 8.8 1.4 8.0 8.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin PF02996.17 EAX71118.1 - 1.1 9.2 11.8 0.22 11.4 5.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF948 PF06103.11 EAX71118.1 - 1.2 9.5 4.7 4.6 7.6 4.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EAX71118.1 - 1.3 9.6 8.6 7.7 7.1 8.4 2.2 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein Tho2 PF11262.8 EAX71118.1 - 1.4 8.0 8.2 2.2 7.4 8.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF349 PF03993.12 EAX71118.1 - 1.7 9.0 6.8 8.3 6.8 3.6 2.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) GTP-bdg_M PF16360.5 EAX71118.1 - 1.8 9.2 4.7 12 6.5 0.7 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Rx_N PF18052.1 EAX71118.1 - 1.9 8.8 6.0 1.7e+02 2.5 6.0 2.5 1 1 0 1 1 1 0 Rx N-terminal domain FemAB PF02388.16 EAX71118.1 - 2.4 6.9 7.0 3.9 6.3 7.0 1.3 1 0 0 1 1 1 0 FemAB family DUF1640 PF07798.11 EAX71118.1 - 3.3 7.7 10.5 5.8 6.9 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YtxH PF12732.7 EAX71118.1 - 5.2 7.7 7.3 44 4.7 7.3 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.6 EAX71118.1 - 5.2 7.2 5.9 8.6 6.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31_Bap29_C PF18035.1 EAX71118.1 - 5.3 7.1 10.9 7.3 6.7 9.9 1.8 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain LMBR1 PF04791.16 EAX71118.1 - 5.8 5.7 4.8 7.9 5.3 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC-167 PF15188.6 EAX71118.1 - 6.3 7.2 10.3 2.1 8.7 7.5 1.6 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Pox_A32 PF04665.12 EAX71119.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71119.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71119.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71119.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX71120.1 - 0.043 14.3 0.5 0.092 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4049 PF13258.6 EAX71121.1 - 0.019 14.1 1.1 0.023 13.8 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) TMP PF05017.14 EAX71122.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX71124.1 - 2.1e-05 24.5 0.6 2.1e-05 24.5 0.6 3.2 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX71124.1 - 0.0029 17.0 0.9 0.0045 16.3 0.9 1.3 1 0 0 1 1 1 1 M penetrans paralogue family 1 DUF4795 PF16043.5 EAX71124.1 - 0.0065 16.1 7.0 0.015 14.9 7.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX71124.1 - 0.014 15.2 1.4 0.02 14.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX71124.1 - 0.024 14.3 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX71124.1 - 0.11 12.9 0.7 0.4 11.2 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) PTR PF12789.7 EAX71126.1 - 6.2e-11 42.2 22.7 2.7e-08 33.7 4.6 4.9 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX71126.1 - 0.0017 18.0 13.7 0.034 13.8 1.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF480 PF04337.12 EAX71126.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 YmaF PF12788.7 EAX71126.1 - 0.39 11.3 10.6 24 5.6 0.1 4.1 3 2 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX71126.1 - 0.95 9.8 20.7 4.7 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF4108 PF13390.6 EAX71128.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71128.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide RSS_P20 PF11757.8 EAX71130.1 - 0.08 13.4 4.0 2.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF2939 PF11159.8 EAX71131.1 - 0.01 16.3 0.6 0.011 16.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Pox_A32 PF04665.12 EAX71132.1 - 8.3e-07 28.7 4.1 8.4e-07 28.7 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX71132.1 - 3.2e-05 23.7 0.4 0.31 10.8 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX71132.1 - 7e-05 23.1 0.2 0.00054 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71132.1 - 0.00027 21.0 4.1 0.00064 19.8 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71132.1 - 0.00069 19.4 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71132.1 - 0.0017 18.2 0.8 0.0055 16.5 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71132.1 - 0.0065 16.1 2.6 0.015 14.9 0.2 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71132.1 - 0.016 15.5 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX71132.1 - 0.093 12.3 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71132.1 - 0.1 13.0 0.1 0.93 9.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71132.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71132.1 - 0.19 12.0 4.6 5.7 7.3 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX71132.1 - 0.99 10.1 11.3 0.52 11.0 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF3781 PF12636.7 EAX71133.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX71134.1 - 3.2e-34 117.2 0.2 4.2e-34 116.7 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX71134.1 - 0.12 12.3 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon T5orf172 PF10544.9 EAX71135.1 - 4.4e-07 30.4 0.1 1e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71135.1 - 0.00072 19.4 0.5 0.0059 16.5 0.1 2.3 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX71135.1 - 0.17 11.4 0.3 0.79 9.2 0.1 1.8 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX71136.1 - 8.6e-33 112.5 0.7 1.6e-32 111.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX71136.1 - 0.35 11.6 2.2 18 6.1 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 PapD_N PF00345.20 EAX71137.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TMP PF05017.14 EAX71138.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX71140.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX71141.1 - 1.7e-156 518.8 13.7 2.1e-156 518.6 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX71141.1 - 1.1 9.6 6.2 0.94 9.8 0.1 3.5 4 1 0 4 4 4 0 PRD domain KELK PF15796.5 EAX71141.1 - 4.3 7.8 7.1 2.3 8.7 0.3 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MG2 PF01835.19 EAX71142.1 - 1.5e-06 28.6 0.4 0.0037 17.7 0.1 3.2 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX71142.1 - 6.4e-06 26.4 1.6 0.018 15.3 0.1 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) NPCBM_assoc PF10633.9 EAX71142.1 - 0.0051 17.0 1.4 0.055 13.7 0.2 3.0 3 1 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase ChitinaseA_N PF08329.10 EAX71142.1 - 0.007 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Chitinase A, N-terminal domain He_PIG PF05345.12 EAX71142.1 - 0.013 15.6 1.9 0.23 11.7 0.1 3.3 2 1 1 3 3 3 0 Putative Ig domain DUF3324 PF11797.8 EAX71142.1 - 0.033 14.2 2.3 0.31 11.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function C-terminal (DUF3324) DUF2914 PF11141.8 EAX71142.1 - 0.04 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) bMG6 PF17962.1 EAX71142.1 - 0.053 13.7 0.2 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 PKD PF00801.20 EAX71142.1 - 0.081 12.8 1.1 0.44 10.4 0.1 2.7 3 1 0 3 3 3 0 PKD domain DUF4106 PF13388.6 EAX71143.1 - 3.5e-97 326.3 5.6 6.2e-97 325.5 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Trypan_PARP PF05887.11 EAX71144.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX71144.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PSP PF04046.16 EAX71145.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71146.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX71148.1 - 0.019 15.0 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71149.1 - 0.0093 16.4 0.3 0.01 16.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) DNA_pol_B_2 PF03175.13 EAX71150.1 - 1.3e-30 106.7 6.4 2.2e-30 106.0 6.4 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX71151.1 - 0.058 13.9 0.4 0.13 12.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Phage_fiber PF03335.13 EAX71152.1 - 0.18 12.0 4.8 1.9 8.8 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat TPR_MLP1_2 PF07926.12 EAX71153.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX71153.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX71153.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX71154.1 - 4.2e-10 39.5 0.0 8.6e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain MtrG PF04210.13 EAX71154.1 - 0.23 11.3 1.2 0.28 11.1 0.2 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G EssA PF10661.9 EAX71154.1 - 0.67 9.8 4.8 1.5 8.6 4.8 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Amidase02_C PF12123.8 EAX71155.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PSP PF04046.16 EAX71158.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71159.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX71162.1 - 1e-55 187.6 7.0 1.1e-55 187.5 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX71163.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX71164.1 - 2.2e-40 137.0 1.1 3.6e-40 136.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71164.1 - 0.016 15.8 0.0 0.05 14.2 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family Acyl_transf_2 PF02273.15 EAX71164.1 - 0.05 12.8 0.2 0.18 11.0 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase DUF3839 PF12943.7 EAX71165.1 - 3e-158 524.6 12.7 3.8e-158 524.2 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX71165.1 - 1.1 9.6 5.0 13 6.2 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX71167.1 - 8.5e-42 141.5 0.1 1.5e-41 140.7 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain LOH1CR12 PF10158.9 EAX71167.1 - 0.21 11.6 2.7 0.71 9.9 0.2 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF3839 PF12943.7 EAX71168.1 - 2e-25 89.7 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX71169.1 - 4.5e-08 32.9 0.5 4.5e-08 32.8 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71169.1 - 0.0048 16.6 0.1 0.0049 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX71169.1 - 0.072 13.1 0.3 0.58 10.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX71169.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein TMP PF05017.14 EAX71170.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat TPR_MLP1_2 PF07926.12 EAX71171.1 - 0.017 15.1 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX71171.1 - 0.062 13.1 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX71171.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX71174.1 - 4.5e-81 271.9 10.4 5.7e-81 271.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX71174.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 DUF2408 PF10303.9 EAX71174.1 - 0.067 13.7 0.3 0.11 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX71175.1 - 6.9e-21 74.6 5.0 1.3e-20 73.8 5.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX71175.1 - 0.013 14.8 0.2 0.021 14.2 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX71175.1 - 0.085 12.9 2.1 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) PapD_N PF00345.20 EAX71176.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71176.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX71177.1 - 3.3e-39 133.2 1.0 6.1e-39 132.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71177.1 - 0.01 16.5 0.1 0.029 15.0 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family RsfS PF02410.15 EAX71177.1 - 0.21 12.0 1.5 2.4 8.7 1.5 2.4 1 1 0 1 1 1 0 Ribosomal silencing factor during starvation TMP PF05017.14 EAX71178.1 - 0.1 13.2 4.6 13 7.0 0.1 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71179.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX71180.1 - 0.026 15.0 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX71180.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4107 PF13389.6 EAX71182.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX71184.1 - 5.8e-121 402.5 11.9 7.3e-121 402.1 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX71184.1 - 0.0085 15.5 0.5 0.014 14.8 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) KELK PF15796.5 EAX71184.1 - 0.045 14.2 2.7 1.6 9.2 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX71184.1 - 0.1 12.4 1.3 0.29 11.0 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX71184.1 - 0.26 11.9 1.5 0.35 11.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX71185.1 - 1.1e-22 80.0 0.7 2.6e-22 78.8 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Pox_D5 PF03288.16 EAX71186.1 - 3.8e-05 24.1 3.4 0.0003 21.2 3.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71186.1 - 0.053 14.1 0.1 0.09 13.4 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71186.1 - 0.061 13.3 0.2 0.09 12.8 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX71187.1 - 8.4e-61 204.1 8.0 9.4e-61 203.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX71188.1 - 0.045 13.5 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX71189.1 - 4.8e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX71189.1 - 0.0059 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX71189.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4108 PF13390.6 EAX71190.1 - 3.1e-54 182.8 7.7 3.4e-54 182.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71190.1 - 0.13 12.6 0.1 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX71191.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX71191.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX71191.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX71192.1 - 8e-07 28.8 2.4 8e-07 28.8 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71192.1 - 3.6e-05 24.1 0.3 0.00026 21.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71192.1 - 4e-05 23.4 0.2 0.32 10.7 0.0 2.5 1 1 0 2 2 2 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71192.1 - 0.00048 20.2 4.7 0.00086 19.3 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71192.1 - 0.00073 19.4 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71192.1 - 0.0021 17.9 1.3 0.0035 17.2 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71192.1 - 0.0055 16.4 2.9 0.012 15.2 0.5 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71192.1 - 0.015 15.6 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX71192.1 - 0.085 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX71192.1 - 0.088 12.4 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71192.1 - 0.11 13.0 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71192.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71192.1 - 0.47 10.7 3.9 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX71192.1 - 0.83 10.3 12.1 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 P22_AR_C PF10548.9 EAX71193.1 - 0.058 13.6 0.2 16 5.8 0.0 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX71193.1 - 0.11 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin TMP PF05017.14 EAX71194.1 - 0.039 14.5 4.2 14 6.9 0.1 3.4 3 1 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX71195.1 - 5.3e-35 119.7 0.7 1.1e-34 118.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX71196.1 - 3.7e-07 30.6 0.2 7.5e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain ResIII PF04851.15 EAX71198.1 - 2.1e-05 24.6 0.7 3.2e-05 24.0 0.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71198.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX71198.1 - 0.0004 20.7 0.0 0.00059 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71198.1 - 0.0019 18.0 0.0 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71198.1 - 0.0069 16.7 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71198.1 - 0.032 13.7 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX71198.1 - 0.061 13.0 0.3 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX71198.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX71198.1 - 0.094 12.3 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX71198.1 - 0.2 11.4 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 EAX71199.1 - 9.1e-23 80.9 4.2 1.3e-22 80.3 4.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Annexin PF00191.20 EAX71201.1 - 0.068 13.3 0.3 0.2 11.7 0.2 1.8 1 1 1 2 2 2 0 Annexin DUF1031 PF06275.11 EAX71201.1 - 0.096 12.9 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) HARE-HTH PF05066.13 EAX71201.1 - 0.12 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain L27_1 PF09058.10 EAX71204.1 - 0.0021 18.0 0.1 0.067 13.2 0.0 2.4 2 0 0 2 2 2 1 L27_1 T5orf172 PF10544.9 EAX71205.1 - 0.00048 20.6 0.2 0.0011 19.4 0.1 1.7 2 0 0 2 2 2 1 T5orf172 domain DUF3839 PF12943.7 EAX71206.1 - 1.5e-37 129.4 3.8 2.1e-37 128.9 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX71206.1 - 0.14 12.6 0.4 1.2 9.7 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB PadR PF03551.14 EAX71207.1 - 0.045 13.7 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family TPR_MLP1_2 PF07926.12 EAX71208.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX71208.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX71208.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family IstB_IS21_ATP PF08483.11 EAX71209.1 - 1.3e-06 28.1 0.2 3e+02 1.4 0.0 8.7 10 0 0 10 10 10 0 IstB-like ATP binding N-terminal WW_FCH_linker PF16623.5 EAX71209.1 - 0.00053 20.7 31.1 19 6.1 1.9 9.1 1 1 7 8 8 8 1 Unstructured linker region between on GAS7 protein LDB19 PF13002.7 EAX71209.1 - 0.0075 16.0 2.1 20 4.8 0.1 3.5 1 1 5 6 6 6 2 Arrestin_N terminal like BORG_CEP PF14957.6 EAX71209.1 - 0.011 17.0 22.5 2.3e+02 2.9 11.9 5.7 2 1 0 2 2 2 0 Cdc42 effector KAAG1 PF15354.6 EAX71209.1 - 0.011 16.2 11.0 8.9 6.9 0.4 3.8 1 1 3 4 4 4 0 Kidney-associated antigen 1 DUF4108 PF13390.6 EAX71210.1 - 2.7e-61 205.7 4.1 3e-61 205.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Methyltr_RsmB-F PF01189.17 EAX71211.1 - 0.065 12.9 0.4 4.4 6.9 0.1 2.1 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DDR PF08841.10 EAX71212.1 - 0.11 11.5 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX71213.1 - 0.18 11.8 9.7 0.28 11.2 9.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.13 EAX71215.1 - 3.3e-23 82.3 4.5 4.1e-23 82.0 4.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_4 PF13637.6 EAX71216.1 - 3.8e-23 81.5 4.2 1.2e-09 38.5 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX71216.1 - 1e-22 80.5 2.6 7.2e-15 55.3 0.6 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX71216.1 - 5.4e-17 60.2 2.5 0.0014 19.0 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX71216.1 - 1.9e-16 59.6 2.2 9.3e-06 25.9 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX71216.1 - 7.7e-15 54.8 4.5 7.6e-05 22.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX71216.1 - 0.00019 21.3 10.4 0.0065 16.4 0.1 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Arg_repressor PF01316.21 EAX71216.1 - 0.12 12.2 0.9 3.7 7.4 0.1 2.9 3 1 0 3 3 3 0 Arginine repressor, DNA binding domain PTR PF12789.7 EAX71217.1 - 8e-06 25.8 4.1 2.1e-05 24.5 0.6 2.9 2 0 0 2 2 2 1 Phage tail repeat like DUF445 PF04286.12 EAX71217.1 - 0.0074 16.1 1.2 0.01 15.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX71217.1 - 0.031 14.7 0.7 0.11 13.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX71217.1 - 0.15 11.7 6.4 0.39 10.3 6.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX71218.1 - 2.3e-57 192.9 4.2 2.6e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71219.1 - 8.9e-05 22.9 2.0 0.00058 20.3 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX71220.1 - 3.4e-79 265.7 10.1 4.5e-79 265.3 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71220.1 - 0.095 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PRD PF00874.20 EAX71220.1 - 0.35 11.2 3.0 0.72 10.2 0.0 2.5 2 1 0 3 3 3 0 PRD domain DUF3221 PF11518.8 EAX71222.1 - 0.027 14.8 1.2 0.051 13.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DNA_pol_B_2 PF03175.13 EAX71223.1 - 4.4e-22 78.6 4.4 5.8e-22 78.2 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71223.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX71224.1 - 5.4e-06 26.0 0.4 6.1e-06 25.9 0.4 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX71224.1 - 0.038 14.3 0.7 0.038 14.3 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) EpuA PF11772.8 EAX71225.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX71225.1 - 0.47 10.6 0.2 0.47 10.6 0.2 3.2 4 0 0 4 4 4 0 Phage tail repeat like Pox_A32 PF04665.12 EAX71230.1 - 5e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX71230.1 - 0.0047 16.9 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX71230.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 HTH_Tnp_4 PF13613.6 EAX71231.1 - 0.002 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF1493 PF07377.12 EAX71232.1 - 0.045 14.2 0.9 0.071 13.6 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX71233.1 - 1.5e-37 127.4 24.2 1.4e-33 114.8 14.2 4.7 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX71233.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX71234.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71234.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71234.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71234.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX71235.1 - 3.4e-77 259.2 8.3 4.4e-77 258.8 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ATG16 PF08614.11 EAX71237.1 - 6.7e-05 23.2 11.1 9.3e-05 22.7 11.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 EAX71237.1 - 9e-05 22.8 25.4 0.0094 16.4 5.3 2.9 2 1 1 3 3 3 2 Cell division protein ZapB DUF3450 PF11932.8 EAX71237.1 - 0.0012 18.3 8.7 0.0012 18.3 8.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) DHR10 PF18595.1 EAX71237.1 - 0.0021 18.1 5.9 0.0021 18.1 5.9 2.3 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain Alpha-L-AF_C PF06964.12 EAX71237.1 - 0.0024 18.0 0.0 0.008 16.3 0.0 1.8 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Fez1 PF06818.15 EAX71237.1 - 0.0033 17.9 14.3 0.0051 17.3 14.3 1.2 1 0 0 1 1 1 1 Fez1 Atg14 PF10186.9 EAX71237.1 - 0.0056 15.8 20.1 0.0087 15.2 20.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 NRBF2 PF08961.10 EAX71237.1 - 0.0068 16.0 16.5 0.049 13.2 5.6 2.4 1 1 1 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator GHL5 PF14872.6 EAX71237.1 - 0.0075 14.4 7.6 0.014 13.5 7.6 1.4 1 0 0 1 1 1 1 Hypothetical glycoside hydrolase 5 APG6_N PF17675.1 EAX71237.1 - 0.01 16.4 18.0 0.023 15.2 17.1 1.9 1 1 1 2 2 2 1 Apg6 coiled-coil region CtIP_N PF10482.9 EAX71237.1 - 0.015 15.3 15.0 0.024 14.7 13.9 2.1 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain UPF0242 PF06785.11 EAX71237.1 - 0.019 15.1 19.9 0.046 13.8 19.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EAX71237.1 - 0.041 14.5 18.2 0.23 12.1 6.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF2968 PF11180.8 EAX71237.1 - 0.043 13.5 5.6 0.072 12.7 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4201 PF13870.6 EAX71237.1 - 0.08 12.7 22.6 0.12 12.0 22.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 EAX71237.1 - 0.092 12.8 18.3 0.67 10.0 13.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 EAX71237.1 - 0.1 13.0 13.4 0.15 12.5 2.9 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF465 PF04325.13 EAX71237.1 - 0.11 12.5 8.7 0.49 10.5 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF465) TMF_TATA_bd PF12325.8 EAX71237.1 - 0.11 12.7 17.1 1.6 8.9 11.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EAX71237.1 - 0.14 11.9 25.6 0.92 9.3 7.9 3.9 1 1 3 4 4 4 0 Septum formation initiator BRE1 PF08647.11 EAX71237.1 - 0.17 11.9 22.2 0.35 11.0 6.5 2.8 1 1 2 3 3 2 0 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 EAX71237.1 - 0.21 11.4 23.9 2.8 7.7 23.8 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Allexi_40kDa PF05549.11 EAX71237.1 - 0.31 10.5 16.6 0.38 10.2 4.7 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4407 PF14362.6 EAX71237.1 - 0.34 10.2 13.4 0.44 9.8 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 EAX71237.1 - 0.37 11.1 5.7 1.4 9.3 5.7 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4530 PF15039.6 EAX71237.1 - 0.37 11.0 3.6 0.62 10.2 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) CENP-H PF05837.12 EAX71237.1 - 0.43 11.0 16.4 1.6 9.2 16.4 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 EAX71237.1 - 0.44 11.2 8.8 1.5 9.5 5.0 2.7 1 1 1 2 2 2 0 SlyX ADIP PF11559.8 EAX71237.1 - 0.48 10.5 24.8 2 8.5 24.3 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 EAX71237.1 - 0.49 10.3 23.0 0.035 14.0 6.3 3.9 3 2 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF724 PF05266.14 EAX71237.1 - 0.68 9.7 20.7 1.5 8.6 8.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) SOGA PF11365.8 EAX71237.1 - 0.79 10.9 15.9 7.8 7.7 0.4 2.5 1 1 1 2 2 2 0 Protein SOGA Ax_dynein_light PF10211.9 EAX71237.1 - 1.2 9.0 20.7 0.11 12.5 13.9 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.9 EAX71237.1 - 1.3 9.2 18.7 4.2 7.6 17.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 EAX71237.1 - 1.3 9.1 22.2 1.7 8.8 5.0 3.5 3 1 1 4 4 3 0 bZIP transcription factor TMPIT PF07851.13 EAX71237.1 - 1.4 8.1 11.0 2.5 7.3 11.0 1.6 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 EAX71237.1 - 2 8.7 18.6 5 7.4 4.7 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIVA PF05103.13 EAX71237.1 - 2.1 8.5 17.1 50 4.0 3.8 2.9 1 1 1 2 2 2 0 DivIVA protein PRKG1_interact PF15898.5 EAX71237.1 - 2.3 9.2 20.7 0.47 11.4 13.2 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2730 PF10805.8 EAX71237.1 - 3.1 8.0 7.5 2.2 8.4 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4200 PF13863.6 EAX71237.1 - 3.3 8.1 20.2 0.4 11.1 10.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Cep57_CLD_2 PF14197.6 EAX71237.1 - 8 6.6 20.2 5.4 7.2 3.0 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 YmaF PF12788.7 EAX71238.1 - 0.054 14.0 1.6 0.73 10.4 1.6 2.1 1 1 0 1 1 1 0 YmaF family Pox_A32 PF04665.12 EAX71239.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71239.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71239.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71239.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DNA_pol_B_2 PF03175.13 EAX71240.1 - 3.2e-17 62.6 4.2 6.4e-17 61.6 4.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX71240.1 - 0.037 13.3 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX71242.1 - 3e-50 170.9 3.1 3.3e-50 170.8 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX71242.1 - 0.16 12.6 1.4 2 9.1 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX71243.1 - 4.1e-17 62.0 0.3 7.2e-17 61.3 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain MtrG PF04210.13 EAX71243.1 - 0.28 11.0 0.9 0.48 10.3 0.2 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G EssA PF10661.9 EAX71243.1 - 1.3 8.9 4.8 3.4 7.5 4.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Pox_D5 PF03288.16 EAX71245.1 - 4.7e-05 23.8 2.6 0.00026 21.4 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71245.1 - 0.024 13.7 0.8 0.033 13.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX71246.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX71247.1 - 9e-23 80.9 4.4 1.3e-22 80.3 4.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KIAA1430 PF13879.6 EAX71248.1 - 0.0089 16.8 2.3 0.011 16.4 2.3 1.2 1 0 0 1 1 1 1 KIAA1430 homologue DUF4108 PF13390.6 EAX71249.1 - 2e-61 206.1 5.8 2.2e-61 205.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX71250.1 - 0.035 14.4 2.2 0.044 14.1 2.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3464 PF11947.8 EAX71250.1 - 0.29 10.9 3.9 0.47 10.2 3.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX71250.1 - 0.72 9.8 5.0 1.5 8.8 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX71252.1 - 6.4e-07 29.9 0.2 1.2e-06 29.0 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71253.1 - 3.8e-40 136.2 0.1 8.8e-40 135.1 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX71253.1 - 0.0028 17.8 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DNA_pol_B_2 PF03175.13 EAX71254.1 - 4.2e-23 82.0 4.1 5.3e-23 81.6 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71254.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) YmaF PF12788.7 EAX71255.1 - 0.18 12.4 1.6 6.9 7.3 0.1 2.1 1 1 0 1 1 1 0 YmaF family PapD_N PF00345.20 EAX71256.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain RHD3 PF05879.12 EAX71259.1 - 0.0026 16.0 2.1 0.0033 15.7 2.1 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Mak16 PF04874.14 EAX71259.1 - 0.086 13.4 0.8 0.44 11.2 0.1 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF4106 PF13388.6 EAX71260.1 - 6.3e-96 322.2 4.1 6.3e-96 322.2 4.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX71260.1 - 0.75 8.3 3.4 0.92 8.0 3.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KilA-N PF04383.13 EAX71261.1 - 5.3e-27 93.9 0.0 7.7e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Pox_D5 PF03288.16 EAX71262.1 - 0.00015 22.2 2.6 0.00089 19.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71262.1 - 0.032 13.3 1.1 0.046 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4107 PF13389.6 EAX71263.1 - 9.3e-73 243.7 3.0 1.2e-72 243.3 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71263.1 - 0.16 12.3 1.0 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX71264.1 - 6.3e-56 186.3 31.0 2.2e-33 114.1 15.5 4.6 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX71264.1 - 0.022 14.5 1.1 0.04 13.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX71265.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71265.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta GPS2_interact PF15784.5 EAX71267.1 - 0.022 15.2 0.4 0.026 14.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAX71267.1 - 0.037 14.4 1.9 0.038 14.4 1.9 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Amidase02_C PF12123.8 EAX71269.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX71269.1 - 0.22 11.4 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX71270.1 - 1.8e-63 212.7 6.3 2e-63 212.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71271.1 - 2.9e-05 24.5 2.8 0.00017 22.0 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71271.1 - 0.011 16.3 0.1 0.024 15.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX71271.1 - 0.015 14.4 1.3 0.02 14.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX71271.1 - 0.026 14.5 0.2 0.065 13.2 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX71272.1 - 5.3e-07 29.3 0.5 2.8e-06 27.0 0.0 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX71272.1 - 0.05 13.2 0.1 1.4 8.5 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71272.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF3839 PF12943.7 EAX71273.1 - 1.3e-140 466.9 8.7 1.5e-140 466.7 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX71275.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX71276.1 - 8.8e-23 80.9 4.0 1.2e-22 80.5 4.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71276.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX71280.1 - 3.8e-66 219.0 53.1 2.7e-32 110.6 18.5 5.3 2 2 2 4 4 4 3 Phage tail repeat like RACo_linker PF17650.1 EAX71280.1 - 0.00054 19.8 0.6 0.47 10.3 0.1 3.3 2 1 1 3 3 3 1 RACo linker region Apolipoprotein PF01442.18 EAX71280.1 - 0.0096 15.8 4.1 0.016 15.1 4.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Peptidase_C78 PF07910.13 EAX71280.1 - 0.021 14.3 3.1 1.5 8.2 0.3 3.2 1 1 2 3 3 3 0 Peptidase family C78 DUF4116 PF13475.6 EAX71280.1 - 0.033 13.9 0.9 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX71280.1 - 0.055 13.8 10.6 1.6 9.1 0.3 4.8 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain GUN4_N PF16416.5 EAX71280.1 - 0.12 12.4 4.4 6.2 6.9 0.2 3.6 1 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal AviRa PF11599.8 EAX71280.1 - 0.2 11.1 5.7 0.43 10.0 1.3 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PSP PF04046.16 EAX71281.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71282.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat JMY PF15871.5 EAX71283.1 - 0.013 14.8 0.5 0.019 14.3 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein GPS2_interact PF15784.5 EAX71284.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX71284.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX71285.1 - 0.054 13.5 9.2 0.069 13.1 9.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX71285.1 - 2.1 8.8 5.8 2.6 8.5 5.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX71286.1 - 1.8e-149 495.8 15.3 2.2e-149 495.5 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71286.1 - 0.11 12.3 0.6 0.4 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX71286.1 - 0.47 11.0 5.3 0.96 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX71286.1 - 0.92 9.9 3.5 0.93 9.8 1.1 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX71286.1 - 1.1 9.8 4.9 4.5 7.8 0.5 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX71287.1 - 2.7e-22 79.3 3.7 3.8e-22 78.8 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71287.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX71288.1 - 4e-07 29.8 0.0 7.7e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein GPS2_interact PF15784.5 EAX71290.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX71290.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX71291.1 - 1.6e-47 159.4 28.1 9.4e-32 108.9 14.4 4.3 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX71291.1 - 0.039 13.7 1.4 0.072 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Poxvirus_B22R_C PF13168.6 EAX71291.1 - 0.099 12.1 0.4 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal Amidase02_C PF12123.8 EAX71292.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX71292.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PSP PF04046.16 EAX71294.1 - 0.068 13.1 0.8 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71295.1 - 0.2 12.4 6.0 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX71295.1 - 5.4 7.0 7.9 5.5 7.0 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3417 PF11897.8 EAX71297.1 - 0.1 13.1 0.5 0.13 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Ly49 PF08391.10 EAX71297.1 - 0.19 12.1 2.0 0.22 11.9 2.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX71297.1 - 0.63 10.0 3.2 1.1 9.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71298.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71298.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3877 PF12993.7 EAX71300.1 - 0.047 13.6 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3839 PF12943.7 EAX71302.1 - 2.9e-114 380.6 7.3 3.3e-114 380.4 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX71304.1 - 1.5e-06 28.7 0.1 3.5e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71304.1 - 0.0058 16.5 1.3 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX71305.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71305.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71305.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71305.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2939 PF11159.8 EAX71306.1 - 0.018 15.4 0.1 0.018 15.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) FAA_hydrolase_N PF09298.11 EAX71306.1 - 0.049 13.8 0.5 0.071 13.3 0.5 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal FAS_N PF17828.1 EAX71307.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX71309.1 - 0.032 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71309.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX71310.1 - 1.1e-156 519.5 13.3 1.3e-156 519.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX71310.1 - 1.6 9.1 5.9 12 6.3 0.0 3.6 4 1 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX71310.1 - 4.3 7.9 8.6 1.2 9.6 0.8 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX71311.1 - 1.9e-07 30.8 0.5 1.7e-06 27.7 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX71311.1 - 0.046 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX71311.1 - 0.056 13.1 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71311.1 - 0.064 13.1 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Clathrin PF00637.20 EAX71312.1 - 3.1e-57 192.5 6.1 9.7e-27 93.6 0.6 3.0 3 0 0 3 3 3 3 Region in Clathrin and VPS TPR_14 PF13428.6 EAX71312.1 - 0.0029 18.3 2.3 1 10.4 0.2 4.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX71312.1 - 0.051 13.8 1.7 0.56 10.6 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAX71312.1 - 0.53 10.4 3.4 7 6.9 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX71312.1 - 0.99 9.7 3.0 2.3 8.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3839 PF12943.7 EAX71313.1 - 3e-140 465.6 15.1 3.9e-140 465.3 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX71314.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71315.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX71316.1 - 1.4e-51 174.2 5.2 1.5e-51 174.1 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VirE PF05272.11 EAX71317.1 - 1.4e-05 24.9 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX71317.1 - 3e-05 24.4 1.8 0.00015 22.1 1.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX71317.1 - 0.048 14.1 0.4 0.16 12.4 0.1 2.0 1 1 1 2 2 2 0 RNA helicase RFX_DNA_binding PF02257.15 EAX71317.1 - 0.08 13.6 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3198 PF11433.8 EAX71317.1 - 0.13 12.2 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) AAA_14 PF13173.6 EAX71317.1 - 0.36 10.9 3.7 7.3 6.6 0.5 2.4 1 1 0 2 2 2 0 AAA domain DUF1493 PF07377.12 EAX71318.1 - 0.017 15.6 0.5 0.032 14.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX71319.1 - 4.9e-157 520.6 14.1 6e-157 520.3 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX71319.1 - 0.092 13.0 0.3 1.7 9.0 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX71319.1 - 0.17 12.3 6.7 0.79 10.2 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ComA PF02679.15 EAX71320.1 - 0.085 12.3 1.0 0.1 12.1 1.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2939 PF11159.8 EAX71321.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71321.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX71322.1 - 0.0074 16.3 0.2 0.0098 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX71323.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX71324.1 - 2.2e-121 403.9 12.6 2.7e-121 403.5 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71324.1 - 0.03 14.8 2.6 1.8 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX71324.1 - 0.17 11.7 1.1 0.53 10.1 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2897 PF11446.8 EAX71326.1 - 0.79 9.6 3.2 1.4 8.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71327.1 - 1.7e-64 216.0 6.3 1.9e-64 215.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71327.1 - 0.1 12.8 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2457 PF10446.9 EAX71328.1 - 2.2 7.3 6.1 3 6.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EpuA PF11772.8 EAX71329.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TMP PF05017.14 EAX71331.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Amidase02_C PF12123.8 EAX71332.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF2939 PF11159.8 EAX71333.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71333.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX71333.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX71333.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX71334.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol3_a_NII PF11490.8 EAX71334.1 - 0.13 12.2 5.9 0.3 11.0 4.5 2.0 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Pox_D5 PF03288.16 EAX71336.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX71337.1 - 2.7e-62 208.9 5.9 3e-62 208.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX71338.1 - 4.3e-27 95.1 8.3 7.1e-27 94.4 8.3 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX71341.1 - 1.5e-79 266.9 10.6 2e-79 266.5 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX71341.1 - 0.095 13.0 1.1 0.24 11.7 1.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DNA_pol_B_2 PF03175.13 EAX71342.1 - 1.4e-23 83.5 10.0 6.1e-23 81.4 10.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX71343.1 - 2e-28 98.2 23.8 6.8e-24 83.7 6.5 4.7 3 1 1 4 4 3 2 Phage tail repeat like DUF3417 PF11897.8 EAX71343.1 - 0.053 14.0 2.4 0.14 12.6 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX71343.1 - 1.4 8.5 25.2 2.3e+02 1.2 16.5 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX71343.1 - 3.2 7.5 12.7 0.1 12.4 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Pox_A32 PF04665.12 EAX71345.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX71345.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Amidase02_C PF12123.8 EAX71346.1 - 0.0098 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase RLL PF10036.9 EAX71349.1 - 0.049 13.5 3.3 0.066 13.0 3.3 1.3 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF2897 PF11446.8 EAX71349.1 - 0.31 10.9 2.8 0.55 10.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX71350.1 - 1.9e-05 25.1 2.6 0.00011 22.6 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71350.1 - 0.02 15.5 0.1 0.036 14.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71350.1 - 0.063 13.3 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Amidase02_C PF12123.8 EAX71351.1 - 0.004 16.8 0.1 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX71352.1 - 2e-25 89.6 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX71352.1 - 0.14 12.6 0.7 0.6 10.6 0.1 1.9 1 1 0 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX71353.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX71353.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF1493 PF07377.12 EAX71354.1 - 0.044 14.2 0.6 0.093 13.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX71355.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Ank_4 PF13637.6 EAX71356.1 - 1.8e-09 38.0 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX71356.1 - 2.1e-08 34.7 0.2 3.7e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX71356.1 - 3.4e-08 33.1 0.0 0.00013 22.1 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX71356.1 - 8.4e-07 29.2 0.1 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX71356.1 - 6.3e-06 26.4 0.1 8e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3839 PF12943.7 EAX71357.1 - 2.6e-29 102.4 6.6 4e-29 101.8 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71357.1 - 0.055 12.6 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX71357.1 - 0.093 13.2 0.3 0.68 10.4 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB RecO_C PF02565.15 EAX71357.1 - 0.2 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal DUF2939 PF11159.8 EAX71358.1 - 0.043 14.2 0.6 0.063 13.7 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF1043 PF06295.12 EAX71359.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TMEM100 PF16311.5 EAX71360.1 - 1.4 8.5 5.8 1.3 8.6 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 PTR PF12789.7 EAX71361.1 - 5.8e-12 45.5 18.8 2.7e-08 33.7 4.6 4.8 4 1 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX71361.1 - 0.00089 18.9 12.8 0.019 14.6 0.6 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF480 PF04337.12 EAX71361.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF480 YmaF PF12788.7 EAX71361.1 - 0.55 10.8 10.3 24 5.5 0.1 4.3 3 1 0 4 4 4 0 YmaF family Phage_fiber PF03335.13 EAX71361.1 - 1.2 9.5 20.9 4.7 7.7 1.1 4.6 4 0 0 4 4 4 0 Phage tail fibre repeat PapD_N PF00345.20 EAX71364.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX71364.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX71364.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MULE PF10551.9 EAX71365.1 - 2.1e-13 50.5 3.0 3e-13 50.0 0.3 2.5 2 1 1 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX71365.1 - 0.01 15.6 0.5 0.042 13.6 0.3 1.9 1 1 1 2 2 2 0 Transposase Transposase_mut PF00872.18 EAX71365.1 - 0.067 12.0 2.7 0.22 10.3 2.7 1.8 1 1 0 1 1 1 0 Transposase, Mutator family DUF2960 PF11173.8 EAX71365.1 - 0.068 13.6 1.5 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) HemX PF04375.14 EAX71366.1 - 0.006 15.9 0.7 0.0069 15.7 0.7 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF641 PF04859.12 EAX71366.1 - 0.02 15.2 1.3 0.032 14.6 1.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 EAX71366.1 - 0.037 14.2 5.4 0.054 13.7 5.4 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EAX71366.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor Gly-zipper_Omp PF13488.6 EAX71367.1 - 0.019 15.0 7.9 0.019 15.0 7.9 1.5 2 0 0 2 2 2 0 Glycine zipper Zincin_2 PF10103.9 EAX71367.1 - 0.17 11.1 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX71367.1 - 0.41 11.0 4.9 0.65 10.3 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX71367.1 - 0.47 10.6 4.2 0.74 9.9 4.2 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Amidase02_C PF12123.8 EAX71368.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX71368.1 - 0.17 11.8 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TMP PF05017.14 EAX71370.1 - 0.036 14.6 4.1 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71371.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX71372.1 - 3.8e-155 514.4 11.8 4.6e-155 514.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX71373.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX71374.1 - 0.11 12.3 0.8 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71375.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4378 PF14309.6 EAX71376.1 - 0.025 14.9 0.3 0.14 12.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX71376.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 La domain HD_3 PF13023.6 EAX71376.1 - 0.14 12.0 1.6 0.2 11.6 0.8 1.6 2 0 0 2 2 2 0 HD domain DUF2897 PF11446.8 EAX71377.1 - 0.67 9.9 2.8 1.2 9.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71378.1 - 3.9e-59 198.7 8.6 4.3e-59 198.5 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71379.1 - 1.7e-05 25.2 2.6 0.00011 22.6 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71379.1 - 0.085 13.5 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain TMP PF05017.14 EAX71381.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71382.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX71383.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71383.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71383.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71383.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71383.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX71383.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX71383.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4795 PF16043.5 EAX71385.1 - 0.0038 16.9 4.3 0.02 14.5 4.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) YvrJ PF12841.7 EAX71386.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Phage_fiber PF03335.13 EAX71388.1 - 1.4 9.3 6.3 6.4 7.2 0.7 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat T5orf172 PF10544.9 EAX71389.1 - 0.0028 18.1 0.1 0.0055 17.2 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71389.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Lectin_legB PF00139.19 EAX71389.1 - 0.08 12.5 1.1 0.23 11.0 0.4 1.8 2 0 0 2 2 2 0 Legume lectin domain Herpes_IE2_3 PF03361.14 EAX71390.1 - 0.014 15.2 0.9 0.52 10.2 0.2 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX71390.1 - 0.016 15.5 3.9 1.2 9.5 0.9 2.6 2 0 0 2 2 2 0 PPP5 TPR repeat region DUF3839 PF12943.7 EAX71391.1 - 9.4e-08 31.8 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX71394.1 - 0.001 19.6 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71394.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX71394.1 - 0.08 12.5 0.4 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Legume lectin domain PTR PF12789.7 EAX71395.1 - 1.1e-53 179.2 38.2 8e-35 118.7 16.3 4.8 3 2 3 6 6 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX71395.1 - 0.078 12.7 1.4 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAX71396.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71397.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71399.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71400.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71401.1 - 0.068 13.1 0.8 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71402.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX71404.1 - 7.8e-41 140.1 1.8 9.4e-41 139.9 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX71405.1 - 9e-79 264.3 9.3 1.2e-78 264.0 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX71406.1 - 0.00014 21.4 2.9 0.0002 20.9 2.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71406.1 - 0.0026 17.4 0.2 0.0034 17.0 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71406.1 - 0.03 14.1 0.3 0.14 11.9 0.2 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX71406.1 - 0.031 13.8 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX71406.1 - 0.043 13.6 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX71406.1 - 0.091 12.7 0.7 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX71406.1 - 0.25 11.5 8.8 4.1 7.6 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX71407.1 - 6.5e-37 127.3 2.7 9.5e-37 126.7 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71407.1 - 0.1 11.7 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Imm70 PF15601.6 EAX71409.1 - 0.27 10.8 3.9 6.9 6.2 0.3 3.0 1 1 3 4 4 4 0 Immunity protein 70 PTR PF12789.7 EAX71410.1 - 8.3e-26 89.8 10.3 8.3e-26 89.8 10.3 3.5 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX71410.1 - 0.051 13.3 1.4 0.077 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) VirDNA-topo-I_N PF09266.10 EAX71410.1 - 0.86 9.8 3.5 3.2 8.0 0.2 2.7 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal DUF4404 PF14357.6 EAX71410.1 - 1.6 9.5 5.1 2.7 8.7 0.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF240 PF03086.14 EAX71410.1 - 2.4 8.1 8.5 1.2 9.1 1.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF240) Amidase02_C PF12123.8 EAX71411.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX71412.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX71415.1 - 0.072 13.6 0.7 0.14 12.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPS2_interact PF15784.5 EAX71416.1 - 0.12 12.8 1.6 0.16 12.4 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX71417.1 - 0.13 12.2 7.5 0.17 11.9 7.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX71419.1 - 4.4e-10 39.5 6.7 7.2e-09 35.6 1.5 4.7 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX71419.1 - 0.13 11.9 12.0 2.7 7.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX71419.1 - 0.31 11.6 7.7 30 5.2 0.1 3.9 3 1 0 3 3 3 0 YmaF family Ank_2 PF12796.7 EAX71420.1 - 2e-34 118.0 1.5 2e-13 50.7 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX71420.1 - 3.8e-34 116.6 3.6 4.8e-10 39.8 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX71420.1 - 5.9e-31 106.1 0.3 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX71420.1 - 1.9e-26 89.2 1.2 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX71420.1 - 8.1e-24 83.0 2.6 0.00026 21.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX71420.1 - 0.0035 17.3 0.7 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Pox_D5 PF03288.16 EAX71421.1 - 3.2e-05 24.3 2.0 0.00016 22.1 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like HD_2 PF12917.7 EAX71423.1 - 0.094 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Pox_A32 PF04665.12 EAX71424.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71424.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71424.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71424.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX71425.1 - 9.6e-08 31.8 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX71426.1 - 1.5e-39 135.9 5.4 2.2e-39 135.4 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX71427.1 - 6.2e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX71427.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX71427.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX71429.1 - 5.1e-97 324.1 6.6 5.7e-97 323.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ARA70 PF12489.8 EAX71432.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3839 PF12943.7 EAX71433.1 - 1.1e-156 519.4 13.6 1.4e-156 519.1 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71433.1 - 0.16 12.4 3.7 4.2 7.9 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX71433.1 - 0.19 11.6 1.7 0.57 10.0 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX71434.1 - 5.1e-158 523.8 12.2 6.1e-158 523.6 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71434.1 - 0.56 10.7 4.9 1.7 9.2 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX71434.1 - 8.7 6.7 7.9 1.2 9.5 0.1 3.2 5 0 0 5 5 5 0 PRD domain DUF3839 PF12943.7 EAX71435.1 - 1.5e-156 519.0 13.7 1.8e-156 518.8 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71435.1 - 0.056 13.3 0.9 0.24 11.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX71435.1 - 0.08 13.2 0.8 1.3 9.3 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX71435.1 - 0.1 13.0 0.4 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX71435.1 - 1.1 9.7 7.8 1.8 9.1 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX71437.1 - 1.1e-07 31.6 1.4 1.3e-07 31.4 1.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71437.1 - 0.0042 16.8 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71437.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71437.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Transposase_mut PF00872.18 EAX71439.1 - 0.06 12.2 1.0 0.25 10.2 0.1 1.9 1 1 0 2 2 2 0 Transposase, Mutator family Amidase02_C PF12123.8 EAX71440.1 - 0.0069 16.0 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX71440.1 - 0.17 11.8 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX71441.1 - 3.7e-07 29.8 0.2 9.1e-07 28.6 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein KilA-N PF04383.13 EAX71442.1 - 1.5e-33 115.0 1.4 1.8e-33 114.7 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71442.1 - 0.0047 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family RsfS PF02410.15 EAX71442.1 - 0.11 13.0 0.6 0.2 12.1 0.6 1.5 1 1 0 1 1 1 0 Ribosomal silencing factor during starvation T5orf172 PF10544.9 EAX71443.1 - 3.8e-07 30.6 0.3 7.2e-07 29.7 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX71443.1 - 0.12 13.0 0.4 0.37 11.5 0.4 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF2897 PF11446.8 EAX71444.1 - 0.44 10.5 3.7 0.81 9.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX71445.1 - 4.1e-05 23.6 2.2 8.3e-05 22.7 2.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71445.1 - 0.0003 20.6 0.0 0.00041 20.1 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX71445.1 - 0.00037 20.8 0.0 0.0006 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71445.1 - 0.00087 19.2 0.7 0.0024 17.7 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71445.1 - 0.0063 16.9 0.0 0.0084 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71445.1 - 0.035 13.6 0.1 0.053 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX71445.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX71445.1 - 0.11 12.0 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX71445.1 - 0.51 10.6 5.5 4.2 7.7 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX71446.1 - 2.3e-71 239.2 3.7 3.1e-71 238.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX71447.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX71449.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX71451.1 - 1.2e-158 525.9 13.4 1.4e-158 525.6 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX71451.1 - 0.11 12.9 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX71451.1 - 0.42 11.1 6.4 2 8.9 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3447 PF11929.8 EAX71453.1 - 1.2 9.1 15.3 0.58 10.1 2.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) HNH_3 PF13392.6 EAX71455.1 - 1.1e-07 31.5 0.2 2.2e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease Tim54 PF11711.8 EAX71455.1 - 0.016 14.0 0.2 0.019 13.8 0.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Radial_spoke PF04712.12 EAX71455.1 - 0.61 9.0 9.3 0.69 8.8 9.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 EAX71455.1 - 5.5 5.0 7.3 6.2 4.8 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mito_fiss_reg PF05308.11 EAX71456.1 - 0.096 12.8 0.5 0.1 12.7 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX71456.1 - 0.51 9.8 2.1 0.48 9.9 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAX71457.1 - 0.075 13.1 0.5 0.08 13.0 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX71457.1 - 0.79 9.1 2.8 0.79 9.1 2.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX71459.1 - 0.024 15.1 0.5 0.05 14.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX71460.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX71461.1 - 3.5e-155 514.5 14.9 4.3e-155 514.2 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX71461.1 - 0.03 14.8 1.9 0.13 12.7 0.3 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX71461.1 - 0.078 12.8 1.3 0.21 11.4 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX71461.1 - 0.28 11.7 6.4 2.1 8.9 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX71461.1 - 0.74 10.4 5.6 0.31 11.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX71464.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX71465.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2939 PF11159.8 EAX71466.1 - 0.016 15.6 0.5 0.02 15.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71466.1 - 1.2 8.1 2.9 1.3 8.0 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX71466.1 - 1.3 9.0 6.0 1.4 8.9 6.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX71467.1 - 7.7e-53 178.3 6.3 8.5e-53 178.1 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71468.1 - 4.9e-05 23.7 2.5 0.00045 20.7 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71468.1 - 0.0097 16.5 0.1 0.02 15.5 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71468.1 - 0.023 14.7 0.2 0.059 13.4 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX71469.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX71469.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71469.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX71469.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX71471.1 - 1.9e-120 400.8 11.7 2.4e-120 400.5 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71471.1 - 0.056 13.9 0.7 5.3 7.6 0.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX71471.1 - 0.098 12.5 0.8 0.3 10.9 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX71472.1 - 1.6e-50 169.0 30.9 6.9e-33 112.5 15.1 3.8 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX71472.1 - 0.031 14.0 0.9 0.062 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX71472.1 - 5.7 7.7 6.5 14 6.4 0.3 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) Mid2 PF04478.12 EAX71473.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX71473.1 - 0.00035 20.3 2.0 0.00055 19.6 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX71473.1 - 0.00094 19.3 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX71473.1 - 0.0026 17.6 0.6 0.003 17.5 0.6 1.4 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX71473.1 - 0.0031 17.4 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX71473.1 - 0.0037 17.5 1.0 0.0052 17.0 1.0 1.4 1 1 0 1 1 1 1 Glycophorin A ECSCR PF15820.5 EAX71473.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4448 PF14610.6 EAX71473.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MtrF PF09472.10 EAX71473.1 - 0.028 13.8 3.5 0.052 12.9 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Orf78 PF06024.12 EAX71473.1 - 0.032 14.5 0.3 0.041 14.2 0.3 1.4 1 1 0 1 1 1 0 Orf78 (ac78) MMM1 PF10296.9 EAX71473.1 - 0.04 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 EphA2_TM PF14575.6 EAX71473.1 - 0.041 14.8 0.1 0.082 13.8 0.0 1.5 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Gemini_mov PF01708.16 EAX71473.1 - 0.048 13.4 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF2207 PF09972.9 EAX71473.1 - 0.057 12.2 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 EAX71473.1 - 0.059 12.8 4.0 0.1 12.0 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 EAX71473.1 - 0.062 13.3 0.3 0.082 12.9 0.3 1.3 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Otopetrin PF03189.13 EAX71473.1 - 0.07 11.9 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Cortexin PF11057.8 EAX71473.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney ODV-E18 PF10717.9 EAX71473.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 EAX71473.1 - 0.14 10.5 2.5 0.16 10.4 2.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) DUF5385 PF17359.2 EAX71473.1 - 0.15 11.6 0.4 0.65 9.5 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Amnionless PF14828.6 EAX71473.1 - 0.18 10.6 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless ASFV_J13L PF05568.11 EAX71473.1 - 3 7.5 4.6 1.7 8.4 1.4 1.8 1 1 1 2 2 2 0 African swine fever virus J13L protein TMP PF05017.14 EAX71474.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX71475.1 - 0.027 14.9 0.5 0.055 13.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX71476.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71476.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71476.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71476.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71476.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71476.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71476.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71476.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX71476.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71476.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71476.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX71476.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX71476.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX71477.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain T5orf172 PF10544.9 EAX71478.1 - 7.4e-05 23.2 0.5 0.00022 21.7 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX71478.1 - 0.0046 16.5 0.4 0.067 12.7 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX71479.1 - 7.2e-12 45.1 0.7 1.1e-11 44.5 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX71479.1 - 0.086 12.2 0.7 0.19 11.1 0.7 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX71479.1 - 4.4 7.1 8.7 13 5.6 8.7 1.7 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA KilA-N PF04383.13 EAX71481.1 - 3.9e-35 120.1 0.7 1.1e-34 118.6 0.1 2.1 2 0 0 2 2 2 1 KilA-N domain DUF4106 PF13388.6 EAX71482.1 - 5e-97 325.8 5.4 5e-97 325.8 5.4 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX71482.1 - 0.08 11.5 3.6 0.1 11.2 3.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SLATT_4 PF18186.1 EAX71482.1 - 0.14 11.8 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF3452 PF11934.8 EAX71482.1 - 0.14 11.7 1.1 0.24 11.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Golgin_A5 PF09787.9 EAX71482.1 - 0.83 9.1 11.5 1.1 8.6 11.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4446 PF14584.6 EAX71482.1 - 2.9 7.9 5.3 0.55 10.2 0.8 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF3839 PF12943.7 EAX71485.1 - 3e-40 138.2 5.0 4.2e-40 137.7 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX71485.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX71485.1 - 0.2 12.1 0.9 1.1 9.8 0.2 2.3 2 1 1 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX71485.1 - 0.35 11.3 2.9 1.4 9.3 1.3 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain FAS_N PF17828.1 EAX71487.1 - 0.0064 16.5 0.2 0.0086 16.1 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX71489.1 - 1.9e-58 197.2 15.2 1e-56 191.6 15.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71489.1 - 0.092 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF2897 PF11446.8 EAX71490.1 - 0.2 11.6 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX71491.1 - 0.0034 17.7 0.0 0.019 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71491.1 - 0.027 14.3 1.4 0.088 12.6 1.4 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX71491.1 - 0.034 13.9 0.0 0.047 13.5 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 EAX71491.1 - 0.041 13.9 4.6 0.077 13.0 4.6 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1827 PF08860.10 EAX71491.1 - 0.14 12.4 3.8 4.4 7.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Exonuc_VII_L PF02601.15 EAX71492.1 - 0.019 14.6 11.7 0.035 13.7 0.3 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit MetOD2 PF18548.1 EAX71492.1 - 0.032 14.3 14.7 0.05 13.7 0.7 3.7 2 1 1 3 3 3 0 Metanogen output domain 2 IFT20 PF14931.6 EAX71492.1 - 0.67 10.1 18.5 0.44 10.7 0.6 2.7 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Fez1 PF06818.15 EAX71492.1 - 1.6 9.2 24.4 1.2e+02 3.0 24.4 2.6 1 1 0 1 1 1 0 Fez1 Laminin_II PF06009.12 EAX71492.1 - 3.2 7.8 12.0 2.3 8.2 6.8 2.6 2 1 0 2 2 2 0 Laminin Domain II NurA PF09376.10 EAX71492.1 - 3.3 7.3 10.9 0.32 10.6 3.1 2.1 1 1 1 2 2 2 0 NurA domain HR1 PF02185.16 EAX71492.1 - 4 7.6 15.6 0.63 10.2 8.1 3.4 3 1 0 3 3 3 0 Hr1 repeat DUF641 PF04859.12 EAX71492.1 - 4.8 7.5 17.9 5.9 7.2 7.1 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.12 EAX71492.1 - 7.4 6.7 24.6 0.045 13.8 4.2 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3839 PF12943.7 EAX71493.1 - 1.3e-149 496.3 13.3 1.7e-149 495.9 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX71493.1 - 0.18 12.1 3.8 11 6.4 0.0 3.7 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX71493.1 - 0.57 10.7 4.0 0.33 11.5 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX71493.1 - 0.64 10.5 4.2 0.86 10.1 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX71494.1 - 2.4e-06 28.0 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71494.1 - 0.022 14.6 1.9 0.1 12.4 1.0 2.4 2 1 0 2 2 2 0 KilA-N domain FYVE_2 PF02318.16 EAX71495.1 - 0.033 14.4 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3839 PF12943.7 EAX71496.1 - 7.8e-160 529.8 13.7 9e-160 529.5 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71496.1 - 0.26 11.1 1.9 1.3 8.9 1.9 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX71496.1 - 1.1 9.8 7.2 1.6 9.2 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX71498.1 - 6.2e-39 133.9 4.9 9e-39 133.4 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71498.1 - 0.03 13.5 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX71498.1 - 0.087 13.3 0.2 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB THOC7 PF05615.13 EAX71498.1 - 0.11 12.8 1.1 0.29 11.4 1.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 KilA-N PF04383.13 EAX71499.1 - 2.5e-43 146.5 0.6 5.8e-43 145.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71499.1 - 0.021 15.4 0.0 0.052 14.2 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF1493 PF07377.12 EAX71500.1 - 0.037 14.5 0.6 0.077 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX71501.1 - 3.9e-08 33.1 1.9 4.7e-08 32.8 1.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71501.1 - 0.0041 16.8 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71501.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71501.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Trypan_PARP PF05887.11 EAX71504.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX71506.1 - 2.6e-07 30.4 0.8 1.3e-06 28.1 0.0 2.2 1 1 1 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX71506.1 - 0.046 13.4 0.1 0.95 9.1 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71506.1 - 0.1 12.4 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX71506.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2939 PF11159.8 EAX71509.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71509.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 T5orf172 PF10544.9 EAX71511.1 - 0.0011 19.5 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX71511.1 - 0.022 14.0 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX71511.1 - 0.022 14.3 0.5 0.047 13.2 0.1 1.6 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX71511.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain Pox_D5 PF03288.16 EAX71513.1 - 7.3e-05 23.2 2.6 0.0004 20.8 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71513.1 - 0.043 12.9 1.3 0.059 12.4 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX71514.1 - 2.8e-58 195.9 5.2 3.1e-58 195.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71514.1 - 0.092 13.0 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4108 PF13390.6 EAX71517.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71520.1 - 5.5e-05 23.6 3.7 0.00038 20.9 3.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71520.1 - 0.064 13.9 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71520.1 - 0.076 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4106 PF13388.6 EAX71522.1 - 1.1e-158 528.9 52.3 2.9e-113 379.3 9.8 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX71522.1 - 0.00028 21.1 0.1 0.019 15.3 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated WYL_3 PF18488.1 EAX71522.1 - 0.2 12.1 6.3 6.7 7.2 0.5 3.5 3 0 0 3 3 3 0 WYL domain BA14K PF07886.11 EAX71522.1 - 1 9.3 5.8 33 4.5 0.2 3.7 1 1 2 3 3 3 0 BA14K-like protein PT PF04886.12 EAX71522.1 - 7.7 6.2 47.9 4.7 6.9 34.5 2.6 1 1 1 2 2 2 0 PT repeat KilA-N PF04383.13 EAX71523.1 - 1.9e-33 114.7 0.2 1.9e-33 114.7 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX71523.1 - 0.0012 19.0 0.1 0.0034 17.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX71523.1 - 0.21 12.1 4.8 0.24 11.9 1.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 T5orf172 PF10544.9 EAX71524.1 - 5.8e-05 23.6 0.0 0.00016 22.2 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71524.1 - 0.029 14.2 2.0 0.064 13.1 0.6 2.3 2 2 0 2 2 2 0 KilA-N domain AAA_22 PF13401.6 EAX71525.1 - 1.8e-05 25.0 0.2 0.00013 22.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71525.1 - 3.2e-05 23.7 0.3 0.44 10.2 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71525.1 - 7.9e-05 22.7 3.1 0.00016 21.8 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71525.1 - 0.00044 20.1 0.1 0.00077 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX71525.1 - 0.00063 19.3 2.3 0.00063 19.3 2.3 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX71525.1 - 0.00094 18.9 0.6 0.01 15.5 0.2 2.2 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX71525.1 - 0.0015 18.4 1.3 0.0044 16.8 1.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71525.1 - 0.0095 16.3 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX71525.1 - 0.035 14.5 0.1 0.3 11.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX71525.1 - 0.037 13.6 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX71525.1 - 0.044 13.3 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX71525.1 - 0.067 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Terminase_6 PF03237.15 EAX71525.1 - 0.089 12.4 0.1 0.25 11.0 0.0 1.7 1 1 0 2 2 2 0 Terminase-like family DUF1827 PF08860.10 EAX71525.1 - 0.34 11.2 5.3 7.4 6.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX71525.1 - 1.8 9.0 6.1 0.35 11.3 1.2 2.3 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 DUF2897 PF11446.8 EAX71526.1 - 7.1 6.6 6.5 15 5.5 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX71527.1 - 3.7e-05 24.2 0.1 0.00047 20.6 0.1 2.3 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX71527.1 - 0.059 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 KilA-N domain DUF3148 PF11347.8 EAX71527.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) TMP PF05017.14 EAX71528.1 - 0.045 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX71529.1 - 0.027 14.9 0.6 0.073 13.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX71530.1 - 5.5e-08 32.7 0.2 5.5e-08 32.7 0.2 2.2 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX71530.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DNA_pol_B_2 PF03175.13 EAX71531.1 - 4.8e-09 35.6 1.3 1e-08 34.5 1.3 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX71531.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX71531.1 - 0.15 12.1 0.1 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor T5orf172 PF10544.9 EAX71532.1 - 2.7e-06 27.9 0.0 6.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71532.1 - 0.01 15.7 1.9 0.069 13.0 0.9 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAX71532.1 - 0.073 14.0 0.2 1.2 10.1 0.0 2.2 2 0 0 2 2 2 0 FRG domain Mito_fiss_reg PF05308.11 EAX71533.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX71533.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FliJ PF02050.16 EAX71534.1 - 0.022 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4106 PF13388.6 EAX71535.1 - 1.8e-93 314.1 5.7 1.8e-93 314.1 5.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF4446 PF14584.6 EAX71535.1 - 2.8 7.9 5.9 0.58 10.1 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) KilA-N PF04383.13 EAX71537.1 - 8.8e-31 106.1 0.1 1.2e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX71538.1 - 5.6e-07 30.0 0.5 1.7e-06 28.5 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX71538.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX71538.1 - 0.1 12.5 1.1 0.52 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain DUF2939 PF11159.8 EAX71539.1 - 0.012 16.0 0.3 0.014 15.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX71540.1 - 0.012 15.6 0.2 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX71541.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX71541.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX71541.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain IstB_IS21 PF01695.17 EAX71543.1 - 2.1e-05 24.3 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX71543.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX71543.1 - 6.5e-05 22.5 2.1 6.5e-05 22.5 2.1 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX71543.1 - 0.0004 20.4 4.9 0.00064 19.8 4.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71543.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71543.1 - 0.0029 17.4 1.7 0.0079 16.0 0.9 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71543.1 - 0.0039 16.9 2.4 0.014 15.1 0.2 2.5 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71543.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX71543.1 - 0.062 13.3 0.7 0.98 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX71543.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71543.1 - 0.077 13.4 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71543.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71543.1 - 0.61 10.4 5.0 8.4 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX71543.1 - 4.5 8.0 11.3 0.35 11.6 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 PadR PF03551.14 EAX71544.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX71544.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX71546.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) UPF0302 PF08864.10 EAX71547.1 - 0.77 9.9 24.2 61 3.7 0.1 9.6 6 4 5 12 12 12 0 UPF0302 domain Pox_A32 PF04665.12 EAX71549.1 - 4e-07 29.8 2.1 5.2e-07 29.4 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71549.1 - 0.0042 16.7 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71549.1 - 0.053 13.0 0.1 0.071 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71549.1 - 0.058 13.1 0.3 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71549.1 - 0.089 12.5 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX71549.1 - 0.16 12.4 3.4 0.5 10.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX71549.1 - 0.18 11.8 2.2 1.3 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX71549.1 - 0.5 10.6 8.3 5.3 7.3 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) TPR_MLP1_2 PF07926.12 EAX71552.1 - 0.033 14.3 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX71552.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX71552.1 - 0.098 12.6 2.7 0.098 12.6 2.7 2.1 2 1 0 2 2 2 0 Spo12 family DUF1493 PF07377.12 EAX71553.1 - 0.053 14.0 0.3 0.11 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX71554.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Vta1 PF04652.16 EAX71555.1 - 0.016 15.2 0.3 0.025 14.5 0.3 1.3 1 0 0 1 1 1 0 Vta1 like Transposase_mut PF00872.18 EAX71555.1 - 0.018 13.9 0.8 0.024 13.5 0.4 1.4 1 1 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX71556.1 - 5.5e-54 183.2 4.2 6.2e-54 183.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX71556.1 - 0.044 13.3 0.2 0.05 13.1 0.2 1.0 1 0 0 1 1 1 0 Z1 domain Pox_A32 PF04665.12 EAX71558.1 - 3.6e-07 29.9 0.0 4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein YmaF PF12788.7 EAX71560.1 - 0.075 13.6 2.0 6.6 7.3 0.2 2.1 1 1 0 2 2 2 0 YmaF family MULE PF10551.9 EAX71561.1 - 9.5e-12 45.2 0.1 1.6e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX71561.1 - 0.099 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 PWI domain Noggin PF05806.12 EAX71562.1 - 0.035 14.0 1.2 0.044 13.7 1.2 1.0 1 0 0 1 1 1 0 Noggin Presenilin PF01080.17 EAX71562.1 - 0.66 8.7 2.0 0.74 8.5 2.0 1.0 1 0 0 1 1 1 0 Presenilin HAUS-augmin3 PF14932.6 EAX71563.1 - 0.038 13.6 1.2 0.056 13.0 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 L_lactis_ph-MCP PF06673.11 EAX71563.1 - 2.2 7.2 4.9 1.1 8.2 1.8 1.9 2 0 0 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein Arm-DNA-bind_5 PF17293.2 EAX71563.1 - 2.6 8.6 11.5 1.2 9.6 7.7 2.5 2 1 0 2 2 2 0 Arm DNA-binding domain DUF4108 PF13390.6 EAX71566.1 - 3e-56 189.3 7.1 3.3e-56 189.2 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71566.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Amidase02_C PF12123.8 EAX71568.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Chal_sti_synt_N PF00195.19 EAX71570.1 - 0.066 12.6 0.2 0.12 11.7 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX71570.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX71571.1 - 7.9e-79 264.5 9.9 1e-78 264.2 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71571.1 - 0.093 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2939 PF11159.8 EAX71572.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71572.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX71573.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX71574.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71575.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX71576.1 - 0.041 14.3 0.2 0.089 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ResIII PF04851.15 EAX71577.1 - 5.4e-05 23.3 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX71577.1 - 6.3e-05 23.3 0.0 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX71577.1 - 0.00044 20.1 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71577.1 - 0.00072 19.4 0.7 0.0021 17.9 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71577.1 - 0.0044 16.8 0.3 0.26 11.0 0.0 2.6 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX71577.1 - 0.0077 16.6 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71577.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX71577.1 - 0.083 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX71577.1 - 0.1 13.0 0.1 0.38 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX71577.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX71577.1 - 0.24 11.6 4.5 5.3 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) His_Phos_2 PF00328.22 EAX71579.1 - 1.6e-06 27.7 0.0 1.6e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MetallophosC PF16370.5 EAX71580.1 - 0.19 11.9 0.0 0.6 10.3 0.0 1.7 2 0 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Mlf1IP PF10248.9 EAX71581.1 - 3.3e-12 46.7 3.7 3.3e-12 46.7 3.7 1.7 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein OHCU_decarbox PF09349.10 EAX71581.1 - 0.024 15.1 1.2 0.032 14.7 1.2 1.2 1 0 0 1 1 1 0 OHCU decarboxylase TMEM214 PF10151.9 EAX71581.1 - 1.4 7.2 14.7 1.6 7.1 14.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator TonB_N PF16031.5 EAX71581.1 - 2.2 8.8 15.1 3.7 8.1 15.1 1.4 1 0 0 1 1 1 0 TonB polyproline region Phage_fiber PF03335.13 EAX71582.1 - 6 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat KilA-N PF04383.13 EAX71583.1 - 5.1e-40 135.8 0.3 1.3e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71583.1 - 0.0061 17.2 0.1 0.018 15.7 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX71584.1 - 2.9e-07 30.2 0.1 4.1e-07 29.7 0.1 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX71586.1 - 3.6e-05 23.6 0.2 3.6e-05 23.6 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71586.1 - 0.0064 17.1 0.1 0.013 16.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX71588.1 - 2.2e-07 30.6 0.7 1.2e-06 28.1 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX71588.1 - 0.06 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71588.1 - 0.099 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX71588.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX71589.1 - 2.7e-06 27.0 1.9 4e-06 26.5 1.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71589.1 - 0.0028 17.3 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71589.1 - 0.043 13.6 0.2 0.19 11.5 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX71589.1 - 0.043 13.3 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX71589.1 - 0.069 12.9 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX71589.1 - 0.16 12.0 2.2 1.2 9.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX71589.1 - 0.42 10.8 8.4 4.7 7.4 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Tubulin PF00091.25 EAX71592.1 - 3.1e-56 190.7 0.0 5.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX71592.1 - 8.4e-39 132.6 0.0 1.4e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAX71592.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAX71592.1 - 0.03 13.5 0.0 0.097 11.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin like DUF3839 PF12943.7 EAX71594.1 - 4.6e-40 137.6 4.6 6.7e-40 137.1 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71594.1 - 0.032 13.4 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX71594.1 - 0.093 13.2 0.2 0.69 10.4 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB THOC7 PF05615.13 EAX71594.1 - 0.11 12.8 1.1 0.27 11.5 1.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Pox_D5 PF03288.16 EAX71595.1 - 0.0001 22.7 2.9 0.00071 20.0 2.9 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX71598.1 - 3.2e-43 147.1 2.9 3.6e-43 146.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX71598.1 - 0.14 11.2 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein FAS_N PF17828.1 EAX71599.1 - 0.012 15.6 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX71600.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX71602.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71603.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71603.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4378 PF14309.6 EAX71604.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) Noggin PF05806.12 EAX71604.1 - 0.17 11.8 0.9 0.31 10.9 0.9 1.3 1 0 0 1 1 1 0 Noggin DUF3839 PF12943.7 EAX71606.1 - 6.3e-08 32.4 1.4 1e-07 31.7 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX71608.1 - 3.4e-08 32.8 3.3 1.6e-07 30.6 3.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX71608.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF1493 PF07377.12 EAX71609.1 - 0.061 13.8 0.5 0.15 12.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX71610.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3781 PF12636.7 EAX71611.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4108 PF13390.6 EAX71613.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX71616.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX71619.1 - 6.1e-62 207.8 8.5 6.8e-62 207.6 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71620.1 - 3.7e-05 24.1 2.6 0.00019 21.8 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71620.1 - 0.075 13.7 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71620.1 - 0.084 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DDE_1 PF03184.19 EAX71622.1 - 1.8e-17 63.6 0.2 4.5e-17 62.3 0.2 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX71622.1 - 5.2e-06 26.3 0.1 0.00044 20.0 0.0 2.8 3 0 0 3 3 3 1 DDE superfamily endonuclease Styelin PF17562.2 EAX71622.1 - 0.0048 17.2 0.5 0.014 15.7 0.5 1.7 1 0 0 1 1 1 1 Styelin DUF512 PF04459.12 EAX71622.1 - 0.064 12.5 1.6 3.3 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF512) DUF4108 PF13390.6 EAX71623.1 - 6.7e-43 146.0 2.9 7.4e-43 145.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX71623.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PcfK PF14058.6 EAX71624.1 - 0.03 14.6 7.4 0.041 14.2 7.4 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX71624.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Gp58 PF07902.11 EAX71625.1 - 0.39 9.0 3.5 0.46 8.7 3.5 1.1 1 0 0 1 1 1 0 gp58-like protein DUF3839 PF12943.7 EAX71626.1 - 1.3e-149 496.3 15.0 1.6e-149 496.0 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX71626.1 - 1.9 9.1 6.1 1.1 9.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX71626.1 - 3.4 8.2 7.1 4.6 7.8 0.3 3.5 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX71628.1 - 0.088 12.7 1.1 0.23 11.3 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX71629.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71629.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71629.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71629.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4795 PF16043.5 EAX71630.1 - 0.025 14.2 27.4 0.6 9.7 5.5 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) DUF2344 PF10105.9 EAX71630.1 - 1.4 8.7 6.0 2.6 7.9 6.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Cag12 PF13117.6 EAX71630.1 - 2.3 8.8 10.2 5 7.7 0.6 3.8 2 1 2 4 4 4 0 Cag pathogenicity island protein Cag12 PTR PF12789.7 EAX71630.1 - 4.8 7.3 12.3 0.3 11.2 3.4 3.6 3 1 0 3 3 3 0 Phage tail repeat like JMY PF15871.5 EAX71632.1 - 0.0088 15.4 0.3 0.013 14.8 0.3 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein Pox_A32 PF04665.12 EAX71637.1 - 7.2e-07 28.9 2.9 7.2e-07 28.9 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71637.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71637.1 - 7.2e-05 22.6 0.2 0.4 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71637.1 - 0.0001 22.3 2.7 0.00021 21.3 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71637.1 - 0.00062 19.6 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71637.1 - 0.0013 18.6 0.7 0.0022 17.8 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71637.1 - 0.0019 17.8 0.5 0.013 15.2 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71637.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX71637.1 - 0.071 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71637.1 - 0.086 13.3 0.1 0.69 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71637.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71637.1 - 0.38 11.0 3.7 12 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX71638.1 - 1.3e-05 25.5 3.3 0.00011 22.7 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71638.1 - 0.027 15.1 0.2 0.051 14.2 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX71639.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX71640.1 - 0.063 13.0 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX71641.1 - 3e-05 23.6 3.2 3.3e-05 23.5 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX71641.1 - 0.0032 17.5 1.1 0.007 16.4 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX71641.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX71641.1 - 0.06 13.6 2.0 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX71642.1 - 1.9e-07 30.8 3.3 3e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71642.1 - 0.0042 16.8 0.2 0.0052 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71642.1 - 0.05 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71642.1 - 0.067 12.9 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71642.1 - 0.094 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) APG12 PF04110.13 EAX71642.1 - 0.16 12.4 2.3 0.22 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1493 PF07377.12 EAX71643.1 - 0.072 13.6 0.6 0.17 12.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX71645.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein PSP PF04046.16 EAX71647.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX71648.1 - 6.8e-70 235.3 2.8 7.6e-70 235.1 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ComA PF02679.15 EAX71649.1 - 0.027 13.9 1.2 0.032 13.7 1.2 1.0 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF3839 PF12943.7 EAX71650.1 - 2.1e-79 266.4 10.3 2.8e-79 266.0 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71650.1 - 0.082 12.8 1.1 0.32 10.8 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX71651.1 - 6.5e-114 379.4 7.6 7.5e-114 379.2 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX71653.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF257 PF03192.13 EAX71654.1 - 0.00097 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX71654.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4107 PF13389.6 EAX71655.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX71656.1 - 2.9e-151 501.7 15.8 3.5e-151 501.4 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71656.1 - 3.8 8.0 8.8 1.4 9.4 0.6 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX71657.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71657.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71657.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71657.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71657.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71657.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71657.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71657.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX71657.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71657.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71657.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71657.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX71659.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71659.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX71660.1 - 2.5e-06 28.0 0.2 5.5e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX71660.1 - 0.012 15.4 0.3 0.061 13.2 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain DUF2939 PF11159.8 EAX71661.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71661.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX71662.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX71663.1 - 5.2e-07 29.4 1.2 5.8e-07 29.2 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71663.1 - 0.0041 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX71663.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX71663.1 - 0.07 13.1 0.3 0.61 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) EF-hand_10 PF14788.6 EAX71664.1 - 0.0026 17.6 0.1 0.0082 16.0 0.1 1.9 1 0 0 1 1 1 1 EF hand DNA_pol_B_2 PF03175.13 EAX71665.1 - 5.5e-23 81.6 4.1 7.1e-23 81.2 4.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4378 PF14309.6 EAX71666.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) La PF05383.17 EAX71666.1 - 0.035 14.2 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 La domain DUF4108 PF13390.6 EAX71668.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX71669.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein PTR PF12789.7 EAX71672.1 - 8.3e-88 288.4 54.4 4.9e-34 116.2 13.6 5.1 3 2 2 5 5 5 3 Phage tail repeat like HigB_toxin PF09907.9 EAX71672.1 - 0.0053 17.0 1.5 25 5.2 0.0 3.8 1 1 3 4 4 4 2 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4116 PF13475.6 EAX71672.1 - 0.025 14.3 0.5 0.062 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX71672.1 - 0.051 13.4 9.0 0.6 9.9 3.7 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) DUF2939 PF11159.8 EAX71673.1 - 0.022 15.2 1.4 0.035 14.5 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71673.1 - 1.6 7.7 4.3 1.8 7.6 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX71673.1 - 1.9 8.5 7.8 2 8.4 7.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spore_II_R PF09551.10 EAX71673.1 - 4.6 7.7 7.4 9.9 6.6 7.4 1.6 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) FAS_N PF17828.1 EAX71674.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX71674.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal EssA PF10661.9 EAX71675.1 - 1.9 8.3 6.2 4.4 7.1 6.2 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DNA_pol_B_2 PF03175.13 EAX71676.1 - 2.7e-09 36.4 0.4 2.8e-09 36.4 0.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pannexin_like PF12534.8 EAX71676.1 - 0.084 11.9 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_22 PF13401.6 EAX71677.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71677.1 - 0.00044 20.3 3.4 0.00079 19.5 3.4 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71677.1 - 0.00059 19.7 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71677.1 - 0.0022 17.8 1.6 0.008 16.0 1.6 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71677.1 - 0.0023 17.7 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX71677.1 - 0.017 15.4 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX71677.1 - 0.021 14.6 0.2 0.03 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX71677.1 - 0.048 13.1 0.1 0.072 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX71677.1 - 0.081 13.3 0.0 0.32 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX71677.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX71677.1 - 0.29 11.4 5.1 5.5 7.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX71678.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX71679.1 - 3.1e-05 24.4 2.8 0.00015 22.2 2.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like YpsA PF06908.11 EAX71679.1 - 0.033 14.2 0.6 0.071 13.1 0.2 1.6 2 0 0 2 2 2 0 YspA SLOG family RFX_DNA_binding PF02257.15 EAX71679.1 - 0.063 13.9 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71679.1 - 0.084 12.9 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX71680.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TPR_MLP1_2 PF07926.12 EAX71681.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX71681.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX71681.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX71682.1 - 2.3e-57 192.9 8.4 2.6e-57 192.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX71684.1 - 1e-09 38.3 7.7 1.1e-08 35.0 0.4 4.3 5 1 0 5 5 5 2 Phage tail repeat like BRO1 PF03097.18 EAX71684.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX71684.1 - 0.22 12.0 8.2 31 5.2 0.1 4.2 4 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX71684.1 - 0.36 10.4 10.6 0.064 12.9 2.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX71684.1 - 0.51 10.4 4.6 3.7 7.6 4.6 2.2 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Phage_fiber PF03335.13 EAX71684.1 - 9.2 6.7 24.5 4.7 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF4106 PF13388.6 EAX71685.1 - 2.9e-252 837.1 15.4 3.3e-252 837.0 15.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX71685.1 - 0.014 15.6 0.1 0.61 10.4 0.1 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated TFIIA PF03153.13 EAX71685.1 - 0.12 12.3 14.3 0.17 11.8 14.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3839 PF12943.7 EAX71686.1 - 1.5e-158 525.5 14.0 1.8e-158 525.3 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71686.1 - 2.2 8.8 8.1 1.9 9.0 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDE_Tnp_ISL3 PF01610.17 EAX71687.1 - 5.9e-06 26.2 0.2 1.2e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Transposase DUF3839 PF12943.7 EAX71690.1 - 7.9e-74 248.2 3.7 9.8e-74 247.8 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX71692.1 - 0.028 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71692.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF257 PF03192.13 EAX71693.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX71693.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX71694.1 - 5.1e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX71694.1 - 0.0051 16.8 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX71694.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PTR PF12789.7 EAX71696.1 - 9.2e-46 153.7 31.1 1.3e-30 105.2 14.8 4.2 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX71696.1 - 0.051 13.3 2.0 0.074 12.8 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX71697.1 - 0.047 14.2 0.5 0.093 13.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX71698.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX71700.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71700.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PSP PF04046.16 EAX71701.1 - 0.39 10.6 4.1 0.24 11.3 0.6 2.5 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX71702.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX71703.1 - 0.03 14.3 12.9 0.032 14.2 12.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX71704.1 - 0.091 13.2 1.6 0.12 12.8 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX71704.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PcfK PF14058.6 EAX71707.1 - 1.8 8.8 14.4 2.9 8.2 14.4 1.4 1 1 0 1 1 1 0 PcfK-like protein PBP_sp32 PF07222.12 EAX71707.1 - 4.6 6.6 8.4 6.4 6.1 8.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4108 PF13390.6 EAX71708.1 - 9.6e-64 213.6 5.8 1.1e-63 213.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX71709.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71709.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71709.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71709.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71709.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX71709.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX71709.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX71710.1 - 6.6e-71 237.7 3.4 8.6e-71 237.3 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX71710.1 - 0.098 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX71712.1 - 8.9e-07 28.6 2.7 1.3e-06 28.0 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX71712.1 - 3.8e-05 23.5 0.3 0.37 10.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX71712.1 - 0.0001 22.6 0.2 0.00077 19.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71712.1 - 0.00022 21.3 3.0 0.00044 20.3 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71712.1 - 0.00037 20.3 0.1 0.00068 19.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71712.1 - 0.0019 18.0 1.3 0.0044 16.8 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71712.1 - 0.0046 16.6 1.6 0.016 14.9 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71712.1 - 0.009 16.4 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX71712.1 - 0.079 12.5 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71712.1 - 0.089 13.2 0.1 0.83 10.1 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71712.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Fibrinogen_BP PF08017.11 EAX71712.1 - 0.12 10.8 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein DUF573 PF04504.14 EAX71712.1 - 0.22 12.2 10.9 0.12 13.0 1.2 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 KilA-N PF04383.13 EAX71715.1 - 1.4e-32 111.9 0.1 2.2e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX71717.1 - 0.0001 22.3 1.3 0.0001 22.3 1.3 3.2 3 1 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX71717.1 - 0.0011 18.3 1.2 0.0011 18.3 1.2 2.4 2 1 1 3 3 3 1 M penetrans paralogue family 1 DUF4116 PF13475.6 EAX71717.1 - 0.025 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX71717.1 - 0.04 14.4 1.8 0.076 13.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) RACo_linker PF17650.1 EAX71717.1 - 0.087 12.7 0.2 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 RACo linker region DUF445 PF04286.12 EAX71717.1 - 0.34 10.7 6.1 0.44 10.3 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CREPT PF16566.5 EAX71717.1 - 0.85 9.8 6.0 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Pox_A32 PF04665.12 EAX71718.1 - 5.3e-07 29.3 2.4 5.3e-07 29.3 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX71718.1 - 3.9e-05 23.5 0.3 0.34 10.6 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX71718.1 - 4.9e-05 23.6 0.2 0.00037 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71718.1 - 0.0002 21.4 3.7 0.00042 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71718.1 - 0.00057 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71718.1 - 0.0016 18.3 0.9 0.0033 17.3 0.9 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71718.1 - 0.0018 18.0 0.4 0.012 15.2 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71718.1 - 0.014 15.8 0.0 0.025 14.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX71718.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71718.1 - 0.081 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX71718.1 - 0.088 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX71718.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71718.1 - 0.32 11.3 4.7 11 6.4 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) PSP PF04046.16 EAX71719.1 - 0.075 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71720.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX71721.1 - 0.02 15.4 0.5 0.038 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX71722.1 - 4.5e-07 29.6 0.2 1.3e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein KilA-N PF04383.13 EAX71723.1 - 2.5e-41 140.0 0.8 5.6e-41 138.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3781 PF12636.7 EAX71724.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX71725.1 - 3.2e-61 206.2 11.9 1.9e-59 200.5 11.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX71727.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX71727.1 - 0.07 13.1 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PSP PF04046.16 EAX71731.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71732.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX71735.1 - 3e-131 438.5 52.5 5e-130 434.5 26.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) SLATT_6 PF18169.1 EAX71735.1 - 3.7 7.1 5.5 0.72 9.4 1.8 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 DUF4107 PF13389.6 EAX71736.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX71736.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4108 PF13390.6 EAX71739.1 - 2.3e-40 137.8 1.6 2.5e-40 137.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX71739.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PapD_N PF00345.20 EAX71741.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX71742.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71742.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX71744.1 - 6.2e-25 88.0 10.7 2.9e-24 85.8 10.6 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX71744.1 - 0.1 12.6 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX71744.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5365 PF17326.2 EAX71745.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) ResIII PF04851.15 EAX71746.1 - 2.6e-05 24.3 0.3 3.1e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71746.1 - 0.00023 21.0 0.0 0.00031 20.5 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX71746.1 - 0.0014 18.9 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71746.1 - 0.0017 18.2 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71746.1 - 0.0054 17.1 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71746.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX71746.1 - 0.077 12.6 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX71746.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain IFT20 PF14931.6 EAX71746.1 - 0.21 11.7 2.6 6.4 7.0 0.4 2.3 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 EF-hand_10 PF14788.6 EAX71747.1 - 0.0015 18.3 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 EF hand FTCD_C PF04961.12 EAX71747.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF2508 PF10704.9 EAX71747.1 - 9.7 6.5 7.9 16 5.7 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) DNMT1-RFD PF12047.8 EAX71750.1 - 0.011 15.8 0.6 0.012 15.7 0.6 1.0 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain CENP-B_dimeris PF09026.10 EAX71750.1 - 0.053 13.9 3.5 0.055 13.9 3.5 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FSAP_sig_propep PF03032.15 EAX71750.1 - 0.25 11.4 6.9 0.4 10.7 6.9 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide PTR PF12789.7 EAX71751.1 - 8.9e-17 60.9 1.9 8.9e-17 60.9 1.9 5.3 3 2 2 5 5 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX71751.1 - 0.017 14.9 0.1 0.059 13.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX71751.1 - 0.11 13.1 5.0 0.86 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX71751.1 - 6.4 6.3 23.4 0.2 11.2 5.8 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX71752.1 - 8.4e-34 115.8 1.0 1.4e-33 115.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX71752.1 - 0.25 12.1 1.3 22 5.8 0.3 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Tantalus PF15386.6 EAX71753.1 - 0.16 12.1 0.7 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Drosophila Tantalus-like DUF4108 PF13390.6 EAX71754.1 - 8.3e-45 152.2 3.1 9.1e-45 152.1 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX71754.1 - 0.078 12.0 0.1 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PTR PF12789.7 EAX71756.1 - 6e-31 106.3 11.4 6e-31 106.3 11.4 3.2 4 0 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX71756.1 - 0.032 13.9 0.2 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX71756.1 - 1.6 8.7 8.2 1.4 8.9 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DDR PF08841.10 EAX71757.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX71757.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX71758.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF5439 PF17507.2 EAX71759.1 - 1.6e-06 28.2 0.0 1.1e+02 3.1 0.0 6.4 7 0 0 7 7 7 0 Family of unknown function (DUF5439) Glyco_hydro_68 PF02435.16 EAX71759.1 - 7e-06 25.1 0.0 18 4.1 0.0 5.3 1 1 5 6 6 6 6 Levansucrase/Invertase IKKbetaNEMObind PF12179.8 EAX71759.1 - 0.00029 20.8 0.0 3.7e+02 1.3 0.0 6.4 7 0 0 7 7 7 0 I-kappa-kinase-beta NEMO binding domain EP400_N PF15790.5 EAX71759.1 - 0.00078 18.4 0.0 79 1.9 0.0 5.2 1 1 6 7 7 7 0 E1A-binding protein p400, N-terminal PSP PF04046.16 EAX71762.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71763.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX71764.1 - 1e-165 552.1 28.4 5e-165 549.8 28.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) PT PF04886.12 EAX71764.1 - 0.0012 18.3 35.2 0.0012 18.3 35.2 2.7 1 1 1 2 2 2 1 PT repeat DUF3391 PF11871.8 EAX71764.1 - 0.91 10.1 15.6 3.8 8.0 4.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3597 PF12200.8 EAX71764.1 - 6.3 7.4 7.6 1.1 9.8 2.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) T5orf172 PF10544.9 EAX71765.1 - 0.0014 19.1 1.0 0.0021 18.6 0.3 1.6 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX71765.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX71765.1 - 0.059 12.9 1.2 0.088 12.3 0.4 1.6 2 0 0 2 2 2 0 Legume lectin domain DUF4106 PF13388.6 EAX71768.1 - 1.3e-96 324.5 5.4 2.7e-96 323.4 5.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX71768.1 - 0.83 8.2 4.1 0.93 8.0 3.5 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4106 PF13388.6 EAX71769.1 - 1.3e-20 74.1 33.3 1.3e-20 74.0 33.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Nucleo_P87 PF07267.11 EAX71769.1 - 8.4 5.1 14.4 8.4 5.1 14.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PapD_N PF00345.20 EAX71770.1 - 0.053 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71770.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mito_fiss_reg PF05308.11 EAX71772.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX71772.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX71773.1 - 0.041 14.3 0.7 0.088 13.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX71774.1 - 3.4e-79 265.7 10.6 4.5e-79 265.3 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX71774.1 - 0.11 13.1 0.6 0.18 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX71774.1 - 0.23 11.3 2.1 0.74 9.7 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase GalP_UDP_transf PF01087.22 EAX71774.1 - 0.42 11.0 2.4 1.7 9.0 1.3 2.1 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX71775.1 - 3.4e-148 491.7 11.9 4.7e-148 491.2 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX71775.1 - 0.032 14.7 0.9 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX71775.1 - 0.69 10.2 3.7 1.7 9.0 0.0 3.1 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX71775.1 - 2.1 8.9 7.2 3.9 8.0 1.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1043 PF06295.12 EAX71776.1 - 0.045 13.7 0.2 0.064 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX71776.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX71777.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71777.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX71779.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX71781.1 - 6.3e-05 23.0 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX71781.1 - 7e-05 23.1 0.1 0.00037 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71781.1 - 0.00033 20.5 0.3 0.64 9.7 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX71781.1 - 0.00041 20.2 0.0 0.00078 19.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71781.1 - 0.0011 18.9 0.9 0.004 17.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71781.1 - 0.0085 16.4 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71781.1 - 0.056 12.9 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX71781.1 - 0.07 13.6 0.1 0.42 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX71781.1 - 0.081 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX71781.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX71781.1 - 0.15 12.3 3.4 8.4 6.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2939 PF11159.8 EAX71783.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71783.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX71784.1 - 0.059 13.4 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta FAS_N PF17828.1 EAX71786.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71787.1 - 0.025 15.0 0.5 0.031 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71787.1 - 1.1 8.2 2.8 1.2 8.1 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX71787.1 - 1.5 8.8 5.6 1.6 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX71788.1 - 1e-117 391.9 7.0 1.1e-117 391.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71788.1 - 0.098 12.5 0.2 0.18 11.6 0.1 1.5 2 0 0 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX71788.1 - 0.46 11.0 2.6 1.2 9.7 1.2 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glyco_hydro_47 PF01532.20 EAX71790.1 - 5e-34 118.0 0.0 5.7e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pox_A32 PF04665.12 EAX71791.1 - 6.2e-07 29.1 2.8 6.2e-07 29.1 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71791.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71791.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71791.1 - 0.00013 22.0 3.1 0.00029 20.9 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71791.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71791.1 - 0.0012 18.7 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71791.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71791.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX71791.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71791.1 - 0.089 13.2 0.1 0.74 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71791.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71791.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX71792.1 - 2.4e-05 24.8 3.2 0.00015 22.2 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like VirE PF05272.11 EAX71793.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.9 EAX71793.1 - 0.038 12.9 0.4 2.9 6.7 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EAX71793.1 - 0.077 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF5067 PF16729.5 EAX71794.1 - 0.035 14.0 1.0 0.044 13.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5067) DUF5118 PF17162.4 EAX71795.1 - 0.75 9.7 3.1 69 3.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5118) Pox_A32 PF04665.12 EAX71798.1 - 7.9e-05 22.2 2.5 0.00014 21.4 2.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein Y_phosphatase2 PF03162.13 EAX71798.1 - 0.0098 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX71798.1 - 0.011 15.8 0.5 0.028 14.4 0.1 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX71798.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 GPS2_interact PF15784.5 EAX71800.1 - 0.14 12.6 1.9 0.19 12.2 1.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain ARA70 PF12489.8 EAX71802.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator KilA-N PF04383.13 EAX71803.1 - 1.1e-33 115.4 0.1 1.1e-33 115.4 0.1 1.9 3 0 0 3 3 3 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX71803.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX71803.1 - 0.11 11.0 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) KilA-N PF04383.13 EAX71804.1 - 2.5e-29 101.4 1.2 4.4e-29 100.6 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain GerD PF17898.1 EAX71805.1 - 0.018 15.0 0.2 0.046 13.7 0.1 1.7 1 1 1 2 2 2 0 Spore germination GerD central core domain HTH_29 PF13551.6 EAX71805.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX71805.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase FAS_N PF17828.1 EAX71806.1 - 0.012 15.6 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71807.1 - 0.018 15.4 0.6 0.027 14.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71807.1 - 2.5 8.1 5.9 2.7 8.0 5.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX71809.1 - 0.04 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71809.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX71811.1 - 6.4e-11 42.1 20.9 1.2e-08 34.9 4.8 4.6 3 1 0 3 3 3 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX71811.1 - 0.015 15.2 7.3 10 6.0 4.9 3.6 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD LIFR_D2 PF17971.1 EAX71811.1 - 0.052 13.8 0.0 16 5.7 0.0 2.5 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain GAGA_bind PF06217.12 EAX71813.1 - 0.065 13.5 5.1 0.08 13.2 5.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX71813.1 - 5.5 7.0 7.8 12 5.8 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71814.1 - 1.3e-63 213.2 6.5 1.4e-63 213.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3213 PF11491.8 EAX71815.1 - 0.042 14.0 0.3 0.098 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX71816.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX71817.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX71820.1 - 0.034 14.6 0.4 0.082 13.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX71820.1 - 0.2 11.8 2.0 7 6.8 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Sec63 PF02889.16 EAX71821.1 - 8.2e-08 31.7 0.0 8.6e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain Amidase02_C PF12123.8 EAX71822.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3781 PF12636.7 EAX71826.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_D5 PF03288.16 EAX71827.1 - 0.00029 21.3 2.8 0.0019 18.7 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71827.1 - 0.041 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX71827.1 - 0.051 14.2 0.2 0.11 13.2 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF2897 PF11446.8 EAX71829.1 - 0.059 13.3 3.0 0.11 12.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX71829.1 - 0.1 13.1 0.4 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) PSP PF04046.16 EAX71830.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71831.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat MULE PF10551.9 EAX71833.1 - 1.2e-11 44.9 0.1 1.8e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain DNA_pol_B_2 PF03175.13 EAX71836.1 - 1.1e-24 87.1 7.8 1.7e-23 83.2 7.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX71836.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX71837.1 - 1.9e-22 79.8 4.2 2.7e-22 79.3 4.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAX71838.1 - 1.9e-05 25.1 0.2 0.00023 21.7 0.1 2.4 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX71838.1 - 0.0051 16.4 0.2 0.66 9.5 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX71838.1 - 0.052 13.4 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 KilA-N domain DUF3148 PF11347.8 EAX71838.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) PTR PF12789.7 EAX71840.1 - 1.1e-23 83.0 7.5 1.1e-23 83.0 7.5 3.8 2 1 2 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX71840.1 - 0.012 15.4 0.1 0.042 13.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX71840.1 - 0.29 11.1 6.4 1.6 8.7 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) Membralin PF09746.9 EAX71841.1 - 1.9 7.5 3.6 2 7.3 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein FAS_N PF17828.1 EAX71842.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX71843.1 - 3e-111 370.7 6.8 3.5e-111 370.5 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX71843.1 - 0.035 13.6 0.5 0.043 13.3 0.5 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX71843.1 - 0.22 12.2 2.0 0.42 11.3 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) AAA_22 PF13401.6 EAX71846.1 - 5.6e-05 23.4 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX71846.1 - 9.1e-05 22.5 3.1 0.00016 21.7 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71846.1 - 0.00038 20.3 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71846.1 - 0.0011 18.8 1.2 0.0039 17.0 1.2 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71846.1 - 0.002 17.9 0.1 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX71846.1 - 0.0076 16.6 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71846.1 - 0.048 13.1 0.1 0.074 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX71846.1 - 0.067 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX71846.1 - 0.1 13.0 0.1 0.39 11.1 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX71846.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX71846.1 - 0.22 11.8 4.5 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX71846.1 - 1 9.8 4.2 0.41 11.1 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 KilA-N PF04383.13 EAX71848.1 - 4.6e-40 135.9 0.1 1.4e-39 134.4 0.1 1.8 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX71848.1 - 0.0072 16.9 0.1 0.02 15.5 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX71850.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein MULE PF10551.9 EAX71851.1 - 2.9e-11 43.6 0.2 3.8e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 MULE transposase domain Amidase02_C PF12123.8 EAX71852.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX71854.1 - 3.5e-31 107.0 9.6 3.5e-31 107.0 9.6 3.2 4 1 0 4 4 4 1 Phage tail repeat like DUF2897 PF11446.8 EAX71855.1 - 0.65 9.9 3.2 1.4 8.8 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX71856.1 - 3e-28 98.9 7.6 4.2e-28 98.4 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX71856.1 - 0.052 12.7 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Pox_A32 PF04665.12 EAX71857.1 - 5.4e-07 29.3 0.9 6.3e-07 29.1 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71857.1 - 0.024 14.3 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX71857.1 - 0.065 13.2 0.4 0.59 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MULE PF10551.9 EAX71860.1 - 0.0018 18.6 0.1 0.004 17.5 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Phage_TAC_12 PF12363.8 EAX71860.1 - 0.11 12.9 2.1 0.7 10.3 0.1 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Trypan_PARP PF05887.11 EAX71861.1 - 0.078 13.0 10.9 0.11 12.5 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX71861.1 - 7.4 7.0 7.7 11 6.4 7.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3446 PF11928.8 EAX71861.1 - 7.5 6.9 11.7 5.3 7.4 4.8 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4108 PF13390.6 EAX71862.1 - 1.3e-42 145.1 2.4 1.5e-42 144.9 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX71862.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX71864.1 - 2.2e-05 24.5 0.2 3e-05 24.1 0.2 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71864.1 - 0.00031 20.6 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX71864.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71864.1 - 0.0016 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71864.1 - 0.0054 17.1 0.0 0.0076 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71864.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX71864.1 - 0.057 13.2 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX71864.1 - 0.069 12.7 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX71864.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX71865.1 - 1.5e-156 519.0 13.6 1.9e-156 518.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX71865.1 - 0.028 14.9 1.2 0.18 12.3 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX71865.1 - 0.44 11.0 6.9 2 8.9 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX71866.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX71866.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX71867.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX71868.1 - 4.8e-10 39.3 23.2 1.4e-09 37.9 0.7 4.7 4 2 1 5 5 5 2 Phage tail repeat like Cas_Csm6 PF09659.10 EAX71868.1 - 0.0021 16.9 0.1 0.0035 16.2 0.1 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) DUF4795 PF16043.5 EAX71868.1 - 0.0027 17.3 11.5 0.071 12.7 1.2 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX71869.1 - 3.8e-07 29.8 0.6 2.6e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX71869.1 - 0.054 13.1 0.2 1.4 8.6 0.2 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX71869.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX71869.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX71870.1 - 1.7e-42 143.8 0.4 4.2e-42 142.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71870.1 - 0.026 15.1 0.0 0.075 13.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX71871.1 - 2.8e-07 31.0 0.2 5.7e-07 30.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX71872.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX71873.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX71873.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4107 PF13389.6 EAX71874.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX71874.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX71875.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) BRO1 PF03097.18 EAX71876.1 - 0.04 12.7 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX71876.1 - 1.2 9.8 5.4 26 5.5 0.1 3.2 3 1 0 3 3 3 0 YmaF family DUF4795 PF16043.5 EAX71876.1 - 3.2 7.3 6.5 25 4.4 6.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX71876.1 - 7.3 7.1 10.3 3.7 8.0 0.4 3.5 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX71876.1 - 9.3 6.4 17.1 0.25 11.4 1.8 4.2 5 1 0 5 5 5 0 Phage tail repeat like DUF4108 PF13390.6 EAX71877.1 - 3.3e-58 195.7 4.5 3.6e-58 195.5 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX71877.1 - 0.09 13.0 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX71878.1 - 1.3e-05 25.6 2.0 6.2e-05 23.4 2.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71878.1 - 0.035 13.2 1.2 0.049 12.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX71878.1 - 0.054 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain T5orf172 PF10544.9 EAX71880.1 - 0.00034 21.1 0.1 0.00069 20.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX71881.1 - 1.2e-16 60.5 1.3 1.2e-16 60.5 1.3 4.0 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX71881.1 - 0.012 15.3 6.4 0.3 10.6 7.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX71884.1 - 1.2e-110 368.7 8.2 1.4e-110 368.4 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX71884.1 - 0.03 13.8 0.8 0.038 13.5 0.8 1.3 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX71884.1 - 0.12 12.8 1.3 0.49 10.9 1.3 2.1 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX71886.1 - 0.024 15.1 1.1 0.043 14.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX71887.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX71889.1 - 1.4e-80 270.3 10.9 1.8e-80 269.9 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX71889.1 - 0.13 12.1 1.2 0.62 9.9 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Aldo_ket_red PF00248.21 EAX71890.1 - 0.032 13.4 0.0 0.033 13.4 0.0 1.0 1 0 0 1 1 1 0 Aldo/keto reductase family DUF4795 PF16043.5 EAX71892.1 - 0.026 14.1 12.4 0.29 10.7 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX71893.1 - 4.3e-121 402.9 11.8 5.3e-121 402.6 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX71893.1 - 0.03 14.8 2.3 1.8 9.0 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF29 PF01724.16 EAX71893.1 - 0.056 13.7 0.2 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX71893.1 - 0.25 11.2 1.6 0.7 9.7 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_D5 PF03288.16 EAX71894.1 - 4e-05 24.0 2.5 0.00026 21.4 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like PSP PF04046.16 EAX71895.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2400 PF09674.10 EAX71896.1 - 0.045 13.7 0.5 0.06 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX71896.1 - 0.062 13.3 0.2 0.08 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX71897.1 - 0.02 15.3 0.7 0.032 14.6 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71897.1 - 1.6 7.7 4.2 1.7 7.6 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX71897.1 - 3 7.8 7.7 3.2 7.7 7.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX71898.1 - 5.3e-34 116.4 0.2 7.2e-34 116.0 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX71898.1 - 0.12 12.4 0.4 0.13 12.2 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF2897 PF11446.8 EAX71899.1 - 1.7 8.6 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX71900.1 - 5.3e-62 208.0 4.6 5.9e-62 207.8 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX71901.1 - 4.7e-07 29.5 0.6 3.7e-06 26.6 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein TK PF00265.18 EAX71901.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX71901.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mito_fiss_reg PF05308.11 EAX71902.1 - 0.11 12.6 0.4 0.11 12.6 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4108 PF13390.6 EAX71903.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) C2-C2_1 PF11618.8 EAX71906.1 - 0.021 14.9 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 ACP_PD PF04336.12 EAX71908.1 - 0.049 14.0 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF4107 PF13389.6 EAX71911.1 - 3.2e-68 229.0 1.8 4.3e-68 228.6 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4588 PF15251.6 EAX71912.1 - 0.045 13.5 0.2 0.065 13.0 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) RNA_helicase PF00910.22 EAX71912.1 - 0.062 13.7 0.3 0.4 11.1 0.0 2.2 1 1 0 2 2 2 0 RNA helicase APG12 PF04110.13 EAX71912.1 - 0.095 13.1 0.9 0.25 11.8 1.1 1.6 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF2897 PF11446.8 EAX71913.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX71914.1 - 1.4e-49 168.7 2.8 1.6e-49 168.6 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX71914.1 - 0.065 12.7 0.2 0.069 12.7 0.2 1.0 1 0 0 1 1 1 0 Z1 domain PTR PF12789.7 EAX71917.1 - 4.3e-21 74.7 6.0 4.3e-21 74.7 6.0 2.8 2 1 0 2 2 2 1 Phage tail repeat like nsp9 PF08710.10 EAX71917.1 - 0.98 9.8 4.6 1.1 9.7 0.1 2.8 2 2 0 2 2 2 0 nsp9 replicase PapD_N PF00345.20 EAX71920.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PSP PF04046.16 EAX71921.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71922.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX71923.1 - 0.076 13.5 0.2 0.13 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX71924.1 - 0.0099 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase GPS2_interact PF15784.5 EAX71925.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX71925.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain LRR_6 PF13516.6 EAX71926.1 - 0.13 12.4 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 Leucine Rich repeat DUF4108 PF13390.6 EAX71928.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX71929.1 - 3.3e-42 142.8 0.6 8e-42 141.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_D5 PF03288.16 EAX71931.1 - 4e-05 24.0 2.5 0.00026 21.4 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX71932.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX71934.1 - 1.1e-10 41.8 0.2 2.2e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 MULE transposase domain Pox_A32 PF04665.12 EAX71936.1 - 7.5e-07 28.9 2.9 7.5e-07 28.9 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX71936.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71936.1 - 6.1e-05 22.8 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71936.1 - 0.00011 22.2 3.1 0.00027 21.0 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71936.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71936.1 - 0.0013 18.6 0.7 0.0033 17.3 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71936.1 - 0.0018 18.0 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71936.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX71936.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71936.1 - 0.085 13.3 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71936.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71936.1 - 0.22 11.8 4.8 3.2 8.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) FAS_N PF17828.1 EAX71937.1 - 0.0066 16.4 0.1 0.0072 16.3 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX71938.1 - 4.2e-44 149.9 2.5 4.6e-44 149.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX71940.1 - 5.8e-107 356.7 7.0 6.5e-107 356.5 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GPI-anchored PF10342.9 EAX71941.1 - 0.069 13.9 0.7 0.069 13.9 0.7 2.4 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ChlI PF13541.6 EAX71941.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase IstB_IS21 PF01695.17 EAX71942.1 - 3e-05 23.8 0.5 0.31 10.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX71942.1 - 3.4e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX71942.1 - 0.00018 21.0 1.8 0.00018 21.0 1.8 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein ResIII PF04851.15 EAX71942.1 - 0.00054 20.0 5.4 0.001 19.1 5.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71942.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71942.1 - 0.0039 17.0 2.1 0.0067 16.2 1.0 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71942.1 - 0.0052 16.4 3.0 0.012 15.2 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71942.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX71942.1 - 0.063 13.3 0.8 1.1 9.4 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX71942.1 - 0.068 12.7 0.0 0.21 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71942.1 - 0.072 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX71942.1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71942.1 - 0.5 10.6 5.1 6.3 7.1 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX71942.1 - 3.2 8.5 11.5 0.23 12.1 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAX71945.1 - 2.6e-56 189.5 6.8 2.9e-56 189.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX71946.1 - 0.049 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3839 PF12943.7 EAX71947.1 - 4e-07 29.7 1.4 6.8e-07 29.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX71948.1 - 6e-74 247.6 4.5 7e-74 247.4 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX71948.1 - 0.13 10.7 1.0 0.18 10.2 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase TMP PF05017.14 EAX71949.1 - 0.031 14.8 3.3 12 7.1 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX71952.1 - 7.2e-05 22.4 2.6 7.4e-05 22.3 1.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX71952.1 - 0.0026 17.8 0.4 0.0094 16.0 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX71952.1 - 0.038 14.3 0.5 0.11 12.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) DUF4108 PF13390.6 EAX71953.1 - 2.4e-61 205.8 8.5 2.7e-61 205.7 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX71956.1 - 2e-05 24.9 0.2 0.00015 22.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX71956.1 - 2.5e-05 24.1 0.3 0.25 11.1 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX71956.1 - 9.8e-05 22.4 3.2 0.0002 21.4 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX71956.1 - 0.00035 20.1 2.3 0.00035 20.1 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX71956.1 - 0.00041 20.2 0.1 0.00076 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX71956.1 - 0.00097 19.0 0.6 0.0037 17.1 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX71956.1 - 0.0012 18.6 0.5 0.0094 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX71956.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX71956.1 - 0.045 13.3 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX71956.1 - 0.051 14.0 0.1 0.48 10.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX71956.1 - 0.056 12.9 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX71956.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX71956.1 - 0.28 11.4 4.3 7.9 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX71957.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71957.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX71957.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX71957.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX71957.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX71957.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PSP PF04046.16 EAX71958.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX71959.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX71960.1 - 7.9e-09 35.3 0.1 1.3e-08 34.6 0.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX71960.1 - 0.00026 20.7 0.0 0.00036 20.2 0.0 1.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX71960.1 - 0.047 13.6 1.4 0.075 12.9 1.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4107 PF13389.6 EAX71961.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) PTR PF12789.7 EAX71962.1 - 8.4e-06 25.7 4.6 8.4e-06 25.7 4.6 6.0 6 2 2 8 8 8 2 Phage tail repeat like DUF4738 PF15889.5 EAX71962.1 - 0.016 15.0 2.0 0.016 15.0 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) DUF4795 PF16043.5 EAX71962.1 - 0.35 10.4 13.4 0.06 13.0 4.6 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAX71963.1 - 0.14 12.8 1.8 37 5.6 0.1 3.4 3 0 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX71964.1 - 4.2e-07 30.5 0.4 8.2e-07 29.5 0.4 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX71964.1 - 0.12 13.0 0.5 0.31 11.8 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX71965.1 - 1.1e-35 121.9 0.6 2e-35 121.0 0.0 1.7 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX71965.1 - 0.0029 18.2 0.0 0.0063 17.1 0.0 1.5 1 0 0 1 1 1 1 Parathyroid hormone family T5orf172 PF10544.9 EAX71966.1 - 2.7e-06 27.9 0.2 5.5e-06 26.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX71967.1 - 0.026 14.5 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71968.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX71968.1 - 1.7 8.7 5.2 1.8 8.6 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3464 PF11947.8 EAX71969.1 - 0.51 10.1 2.5 0.91 9.3 2.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX71970.1 - 3.9e-60 201.9 8.9 4.4e-60 201.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX71971.1 - 5.5e-31 106.4 21.2 2.9e-23 81.7 7.3 3.5 3 0 0 3 3 3 2 Phage tail repeat like DUF4795 PF16043.5 EAX71971.1 - 0.00013 21.7 14.8 0.021 14.4 8.3 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX71971.1 - 0.008 16.7 5.9 0.57 10.8 1.1 3.1 3 0 0 3 3 3 2 YmaF family DUF445 PF04286.12 EAX71971.1 - 0.044 13.6 3.9 0.064 13.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX71971.1 - 0.061 13.8 0.2 0.28 11.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Transposase_24 PF03004.14 EAX71971.1 - 0.17 12.0 4.8 0.22 11.7 2.8 2.3 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF4108 PF13390.6 EAX71973.1 - 5.5e-58 194.9 4.4 6.1e-58 194.8 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX71974.1 - 3.2e-05 24.3 3.2 0.00021 21.7 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX71974.1 - 0.051 14.2 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX71974.1 - 0.094 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX71976.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX71977.1 - 0.079 13.2 2.8 0.12 12.7 2.8 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX71977.1 - 3.5 7.6 6.8 1.4 8.9 4.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX71979.1 - 1.6e-50 169.0 38.0 2e-28 98.2 15.7 3.8 4 1 1 5 5 5 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX71979.1 - 1.1 9.6 4.5 39 4.7 0.2 3.6 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain Sec63 PF02889.16 EAX71982.1 - 2.4e-10 40.0 0.0 2.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EAX71982.1 - 8.4e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX71982.1 - 0.00081 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol_B_2 PF03175.13 EAX71983.1 - 4e-16 59.0 1.2 9.2e-16 57.8 1.2 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX71983.1 - 0.029 13.7 0.4 0.042 13.1 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein VirE PF05272.11 EAX71984.1 - 1.6e-05 24.7 0.1 2.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX71984.1 - 0.00028 21.3 2.3 0.0016 18.9 2.3 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71984.1 - 0.013 14.5 0.8 0.021 13.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX71984.1 - 0.08 13.3 0.1 0.17 12.3 0.1 1.7 1 1 0 1 1 1 0 RNA helicase DUF4108 PF13390.6 EAX71985.1 - 3.4e-53 179.4 5.8 3.7e-53 179.3 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX71986.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX71986.1 - 8.2 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX71987.1 - 2.1e-05 24.6 0.8 3.6e-05 23.8 0.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX71987.1 - 0.00029 20.6 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX71987.1 - 0.00038 20.8 0.0 0.00057 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX71987.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX71987.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX71987.1 - 0.033 13.6 0.1 0.044 13.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX71987.1 - 0.058 13.1 0.3 0.1 12.2 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX71987.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX71987.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX71987.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX71987.1 - 0.35 10.4 3.6 0.096 12.2 0.9 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase APG12 PF04110.13 EAX71987.1 - 0.52 10.8 3.2 0.36 11.3 0.5 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Vac_Fusion PF02346.16 EAX71987.1 - 2.1 8.1 5.4 13 5.5 0.4 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Pox_A32 PF04665.12 EAX71988.1 - 0.00015 21.3 0.2 0.00017 21.1 0.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DUF2805 PF10985.8 EAX71988.1 - 0.064 13.6 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Epimerase_2 PF02350.19 EAX71988.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF1493 PF07377.12 EAX71989.1 - 0.044 14.2 0.3 0.084 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX71989.1 - 0.45 10.6 3.3 9.9 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_D5 PF03288.16 EAX71990.1 - 0.22 12.0 3.8 1.3 9.5 3.8 2.2 1 1 0 1 1 1 0 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX71991.1 - 2.3e-159 528.2 14.8 2.9e-159 527.9 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX71991.1 - 0.12 12.8 2.0 0.24 11.9 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX71991.1 - 0.96 9.9 6.5 2.1 8.9 0.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX71992.1 - 1.2e-07 32.2 0.4 2.4e-07 31.2 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX71993.1 - 1.6e-53 178.6 32.1 9.2e-33 112.1 17.3 5.9 3 3 1 4 4 4 2 Phage tail repeat like DUF3391 PF11871.8 EAX71993.1 - 0.0026 18.3 2.5 0.19 12.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX71993.1 - 0.013 15.2 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX71993.1 - 0.7 10.3 3.8 16 5.9 0.2 3.5 2 1 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF4795 PF16043.5 EAX71993.1 - 5.8 6.5 24.7 0.16 11.6 6.1 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) FAS_N PF17828.1 EAX71994.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX71995.1 - 0.012 16.0 0.8 0.015 15.7 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX71995.1 - 2 7.4 4.3 2.1 7.3 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX71995.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX71995.1 - 6.1 6.8 7.6 6.8 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_D5 PF03288.16 EAX71996.1 - 6.9e-05 23.3 2.7 0.00038 20.9 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX71996.1 - 0.016 14.3 0.8 0.023 13.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX71997.1 - 3.4e-53 179.4 5.8 3.7e-53 179.3 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX71999.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PadR PF03551.14 EAX72001.1 - 0.019 14.9 0.0 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family ResIII PF04851.15 EAX72002.1 - 4.5e-05 23.5 2.8 7.8e-05 22.7 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX72002.1 - 0.00012 22.3 0.0 0.00041 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX72002.1 - 0.0004 20.2 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72002.1 - 0.0012 18.7 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72002.1 - 0.0019 17.9 0.2 0.18 11.5 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX72002.1 - 0.0093 16.3 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX72002.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72002.1 - 0.051 13.3 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX72002.1 - 0.057 13.1 0.4 0.089 12.4 0.2 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF1827 PF08860.10 EAX72002.1 - 0.1 12.8 4.5 2.3 8.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA PF00004.29 EAX72002.1 - 0.13 12.7 0.0 0.38 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX72002.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX72002.1 - 0.22 11.2 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX72002.1 - 0.38 11.2 4.4 0.17 12.3 1.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4107 PF13389.6 EAX72004.1 - 2.6e-29 102.5 4.4 1.6e-26 93.4 2.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX72005.1 - 1.2e-30 106.8 2.5 1.4e-30 106.6 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_4 PF13637.6 EAX72006.1 - 1.8e-39 133.6 6.6 5.9e-12 45.9 0.1 5.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX72006.1 - 4.6e-38 129.7 18.1 1.9e-16 60.4 4.7 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX72006.1 - 6.6e-37 124.4 6.5 7.6e-07 29.3 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX72006.1 - 3.4e-35 119.6 8.0 8.4e-11 41.9 0.2 5.1 2 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX72006.1 - 2.8e-26 88.7 8.0 0.00012 22.2 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX72006.1 - 4.7e-22 77.7 8.1 4.7e-22 77.7 8.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) YcxB PF14317.6 EAX72006.1 - 0.0018 17.9 0.0 19 5.0 0.0 4.2 5 0 0 5 5 5 0 YcxB-like protein PH_8 PF15409.6 EAX72006.1 - 0.0092 16.2 0.6 12 6.2 0.0 3.9 1 1 3 4 4 4 1 Pleckstrin homology domain CEP44 PF15007.6 EAX72006.1 - 0.0098 16.1 2.7 13 5.9 0.0 4.0 2 1 3 5 5 5 1 Centrosomal spindle body, CEP44 PrmC_N PF17827.1 EAX72006.1 - 0.2 12.2 0.3 1.3e+02 3.2 0.0 3.1 1 1 2 3 3 3 0 PrmC N-terminal domain MCC-bdg_PDZ PF10506.9 EAX72006.1 - 1.3 9.1 3.7 16 5.6 0.1 3.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3839 PF12943.7 EAX72007.1 - 4.6e-128 425.7 8.4 5.3e-128 425.5 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72007.1 - 0.09 12.3 0.1 0.28 10.7 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX72007.1 - 0.37 11.3 1.9 1.3 9.6 0.9 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX72007.1 - 0.39 11.0 2.1 2.4 8.5 0.0 2.7 2 1 0 2 2 2 0 Rx N-terminal domain DUF2960 PF11173.8 EAX72008.1 - 0.043 14.3 0.3 0.12 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) TALPID3 PF15324.6 EAX72009.1 - 1.2 6.8 13.9 1.4 6.5 13.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF4107 PF13389.6 EAX72010.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72010.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX72011.1 - 2.4e-17 62.8 0.8 5e-17 61.8 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72011.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX72012.1 - 2.5e-10 39.8 2.8 1.4e-09 37.4 2.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72012.1 - 0.11 12.4 0.1 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor EpuA PF11772.8 EAX72013.1 - 0.025 14.2 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF2897 PF11446.8 EAX72014.1 - 0.051 13.5 3.0 0.12 12.3 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX72014.1 - 0.06 13.8 0.2 0.073 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX72015.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX72017.1 - 2.5e-10 40.2 5.9 2.2e-08 34.0 1.4 4.7 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX72017.1 - 0.71 9.4 13.6 0.7 9.5 3.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX72017.1 - 1.2 9.8 10.3 24 5.5 0.2 4.2 4 1 0 4 4 4 0 YmaF family Phage_fiber PF03335.13 EAX72017.1 - 9.3 6.7 24.5 4.7 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF4106 PF13388.6 EAX72018.1 - 3.1e-181 603.2 18.6 4.9e-181 602.5 18.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX72018.1 - 0.0081 16.4 0.1 0.51 10.7 0.2 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX72018.1 - 0.1 13.2 0.7 0.26 11.9 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX72018.1 - 0.2 12.1 6.5 6.8 7.1 0.4 3.6 3 0 0 3 3 3 0 WYL domain PadR PF03551.14 EAX72020.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TMP PF05017.14 EAX72021.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat CRS1_YhbY PF01985.21 EAX72023.1 - 0.058 13.6 0.2 0.09 13.0 0.2 1.3 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Pox_A32 PF04665.12 EAX72024.1 - 4.5e-05 23.0 2.6 4.5e-05 23.0 2.6 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX72024.1 - 0.0039 17.2 1.1 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX72024.1 - 0.045 14.0 1.5 0.12 12.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX72025.1 - 4.9e-38 130.9 4.1 7.1e-38 130.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX72025.1 - 0.21 12.1 1.0 1.2 9.6 0.2 2.1 1 1 0 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX72026.1 - 3.2e-14 52.7 0.3 3.7e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72026.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Amidase02_C PF12123.8 EAX72029.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX72030.1 - 2.7e-40 136.7 0.5 5.8e-40 135.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72030.1 - 0.012 16.2 0.2 0.032 14.9 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX72032.1 - 3.2e-18 65.8 3.5 4e-18 65.5 3.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX72033.1 - 0.019 15.4 0.7 0.025 15.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX72033.1 - 1.3 8.0 2.7 1.4 7.8 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX72033.1 - 2.5 8.1 5.8 2.7 8.0 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX72034.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX72035.1 - 4.2e-152 504.5 13.5 4.9e-152 504.2 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72035.1 - 0.033 14.1 0.4 0.064 13.1 0.4 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX72035.1 - 0.038 14.4 0.3 0.96 9.9 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4108 PF13390.6 EAX72036.1 - 2.1e-61 206.0 7.8 2.3e-61 205.9 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX72037.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX72037.1 - 8.5 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2939 PF11159.8 EAX72038.1 - 0.027 14.9 0.6 0.031 14.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX72038.1 - 1.4 7.9 3.6 1.5 7.8 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein FAS_N PF17828.1 EAX72039.1 - 0.026 14.5 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX72039.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF3839 PF12943.7 EAX72040.1 - 1.6e-131 437.1 17.7 2.2e-131 436.6 17.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX72040.1 - 0.0016 18.9 1.1 0.0055 17.2 0.1 2.5 2 1 0 2 2 2 1 T5orf172 domain ATP-synt_F6 PF05511.11 EAX72040.1 - 0.17 12.3 1.6 21 5.6 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 KELK PF15796.5 EAX72040.1 - 0.32 11.5 3.7 6.4 7.3 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GCN5L1 PF06320.13 EAX72040.1 - 0.33 11.1 2.2 0.57 10.3 0.1 2.5 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF4106 PF13388.6 EAX72041.1 - 2.3e-240 798.0 20.3 4.1e-240 797.1 20.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX72041.1 - 0.005 17.1 0.2 0.28 11.5 0.3 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated PTR PF12789.7 EAX72042.1 - 2.9e-55 184.2 34.0 1.7e-34 117.7 14.8 4.7 3 2 2 5 5 5 2 Phage tail repeat like DUF3839 PF12943.7 EAX72044.1 - 3.5e-97 324.6 7.3 3.9e-97 324.5 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX72044.1 - 0.038 13.5 0.3 0.049 13.1 0.3 1.2 1 1 0 1 1 1 0 Z1 domain Amidase02_C PF12123.8 EAX72046.1 - 0.0021 17.7 0.0 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX72046.1 - 0.17 11.7 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX72048.1 - 1.7e-33 114.8 0.1 1.7e-33 114.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX72048.1 - 0.0057 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) HNH_3 PF13392.6 EAX72049.1 - 1.1e-05 25.1 0.2 1.9e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Ank_5 PF13857.6 EAX72050.1 - 1.1e-19 70.2 1.4 9.6e-11 41.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX72050.1 - 1.9e-19 69.7 1.5 7.9e-13 48.6 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX72050.1 - 5.1e-19 68.6 1.6 8.2e-09 35.9 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX72050.1 - 4.3e-18 64.9 0.8 1.6e-07 31.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX72050.1 - 4.6e-18 63.4 0.6 1.4e-06 28.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat MetallophosN PF16371.5 EAX72050.1 - 0.03 14.6 0.0 5.9 7.2 0.0 2.1 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase DUF4231 PF14015.6 EAX72050.1 - 0.069 13.6 0.0 11 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Stap_Strp_toxin PF01123.20 EAX72050.1 - 0.073 13.9 0.6 0.54 11.2 0.2 1.9 1 1 1 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain RNAse_A_bac PF18431.1 EAX72050.1 - 0.11 13.5 0.1 3.1 8.8 0.1 2.1 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain JMY PF15871.5 EAX72052.1 - 0.012 15.0 0.6 0.017 14.4 0.6 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX72052.1 - 0.13 12.2 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX72052.1 - 0.41 10.7 2.5 0.51 10.4 0.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DNA_pol_B_2 PF03175.13 EAX72053.1 - 3.1e-21 75.8 5.2 3.8e-21 75.5 5.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX72053.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX72054.1 - 9.8e-06 25.2 0.5 1.2e-05 24.9 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX72054.1 - 0.041 13.8 0.4 0.39 10.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX72055.1 - 5.6e-32 109.9 0.2 1.4e-31 108.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX72055.1 - 0.021 15.5 1.2 11 6.8 0.2 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Parathyroid PF01279.17 EAX72055.1 - 0.043 14.4 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family PTR PF12789.7 EAX72056.1 - 3.1e-37 126.4 34.5 4.8e-33 113.0 13.8 3.5 1 1 2 3 3 3 3 Phage tail repeat like YmaF PF12788.7 EAX72056.1 - 0.15 12.6 11.3 0.74 10.4 11.2 2.0 1 1 0 1 1 1 0 YmaF family PH_TFIIH PF08567.11 EAX72056.1 - 1.5 9.2 5.2 16 5.9 0.2 3.1 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain Pox_D5 PF03288.16 EAX72058.1 - 1.6e-05 25.3 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72058.1 - 0.071 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX72059.1 - 2.4e-56 189.6 4.0 2.7e-56 189.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3417 PF11897.8 EAX72060.1 - 0.1 13.0 0.2 0.13 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX72060.1 - 0.17 11.8 2.0 0.31 10.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX72060.1 - 0.74 10.2 3.4 0.79 10.1 3.4 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pox_A32 PF04665.12 EAX72061.1 - 7.5e-07 28.9 2.3 7.5e-07 28.9 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72061.1 - 2.6e-05 24.5 0.2 0.0002 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72061.1 - 3.9e-05 23.4 0.3 0.32 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72061.1 - 0.00012 22.1 2.9 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72061.1 - 0.00051 19.8 0.1 0.00092 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72061.1 - 0.0015 18.3 0.7 0.0049 16.7 0.4 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72061.1 - 0.0018 17.9 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72061.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72061.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX72061.1 - 0.066 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX72061.1 - 0.085 13.3 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72061.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72061.1 - 0.35 11.1 4.0 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) EssA PF10661.9 EAX72062.1 - 5.5 6.8 9.3 14 5.5 9.3 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PTR PF12789.7 EAX72063.1 - 5.2e-55 183.4 32.3 8.4e-33 112.2 16.3 3.7 3 1 1 4 4 4 2 Phage tail repeat like Gly-zipper_Omp PF13488.6 EAX72064.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX72064.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX72064.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ARA70 PF12489.8 EAX72065.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF4107 PF13389.6 EAX72067.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) CD99L2 PF12301.8 EAX72068.1 - 0.05 13.9 1.3 0.053 13.8 0.2 1.6 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF347 PF03988.12 EAX72068.1 - 0.059 13.6 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF4108 PF13390.6 EAX72070.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TSP_NTD PF17804.1 EAX72072.1 - 0.032 14.5 1.0 0.049 13.9 0.9 1.4 1 1 0 1 1 1 0 Tail specific protease N-terminal domain DUF2897 PF11446.8 EAX72074.1 - 4.7 7.2 7.8 11 6.0 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX72075.1 - 1.4e-19 70.0 0.4 3.9e-19 68.6 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72075.1 - 0.0079 16.8 0.1 0.023 15.3 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family KilA-N PF04383.13 EAX72076.1 - 1.3e-23 82.9 0.9 2.4e-23 82.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain ThiS PF02597.20 EAX72080.1 - 0.11 13.1 0.1 8.1 7.2 0.1 2.4 2 0 0 2 2 2 0 ThiS family IKKbetaNEMObind PF12179.8 EAX72080.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain KilA-N PF04383.13 EAX72081.1 - 1e-18 67.2 0.1 1.3e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72081.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX72082.1 - 7.3e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX72082.1 - 0.096 13.1 1.2 0.37 11.2 0.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB FliJ PF02050.16 EAX72083.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX72084.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX72085.1 - 6.7e-61 204.4 7.3 7.5e-61 204.3 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Btz PF09405.10 EAX72086.1 - 0.033 14.5 2.8 0.035 14.4 2.8 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding GGDEF PF00990.21 EAX72086.1 - 0.039 13.7 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX72086.1 - 1.8 8.5 3.8 3.1 7.8 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1493 PF07377.12 EAX72087.1 - 0.036 14.5 0.8 0.073 13.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ank_2 PF12796.7 EAX72088.1 - 7.1e-66 218.8 30.8 7.3e-21 74.6 3.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX72088.1 - 1e-45 152.2 11.2 2.9e-08 33.8 0.2 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX72088.1 - 1.6e-40 132.4 12.7 5.1e-07 29.5 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX72088.1 - 7.6e-39 131.6 8.9 1.9e-13 50.6 0.3 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX72088.1 - 4e-32 109.8 11.0 1.8e-09 37.7 0.2 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) CEP44 PF15007.6 EAX72088.1 - 0.0031 17.7 0.2 40 4.4 0.0 4.5 2 1 4 6 6 6 0 Centrosomal spindle body, CEP44 AMNp_N PF10423.9 EAX72088.1 - 0.085 12.5 0.0 0.34 10.5 0.0 1.8 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus DUF3447 PF11929.8 EAX72088.1 - 0.48 10.4 4.3 1.4 9.0 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) PapD_N PF00345.20 EAX72089.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72089.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX72092.1 - 7.2e-07 28.9 4.0 9.4e-07 28.5 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72092.1 - 2.7e-05 24.5 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72092.1 - 4.7e-05 23.2 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72092.1 - 0.00012 22.2 2.8 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72092.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72092.1 - 0.0012 18.7 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72092.1 - 0.0018 18.0 0.4 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72092.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX72092.1 - 0.066 12.7 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX72092.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72092.1 - 0.084 13.3 0.1 0.71 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72092.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72092.1 - 0.31 11.3 3.7 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX72094.1 - 6.6e-122 405.6 13.3 8.2e-122 405.3 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72094.1 - 0.045 14.2 3.1 1.8 9.0 0.0 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Alpha-amylase PF00128.24 EAX72095.1 - 3e-06 27.1 0.0 5.8e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Kazal_1 PF00050.21 EAX72095.1 - 0.0095 15.9 0.7 0.021 14.8 0.7 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Malt_amylase_C PF16657.5 EAX72095.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Amidase02_C PF12123.8 EAX72096.1 - 0.0098 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX72097.1 - 3.5e-120 399.9 11.7 4.4e-120 399.6 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72097.1 - 0.063 13.7 1.5 11 6.6 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX72097.1 - 0.077 12.5 0.1 0.27 10.7 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX72097.1 - 0.22 11.4 1.9 0.54 10.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase FAS_N PF17828.1 EAX72098.1 - 0.018 15.0 0.2 0.026 14.5 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72099.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72099.1 - 1.5 8.8 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX72100.1 - 3e-05 24.0 0.6 3e-05 24.0 0.6 4.6 4 1 1 5 5 5 1 Phage tail repeat like MeaB PF03308.16 EAX72100.1 - 0.03 13.3 2.0 0.048 12.6 2.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX72100.1 - 0.063 13.1 5.1 0.096 12.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX72100.1 - 0.081 12.6 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX72100.1 - 0.45 11.0 0.1 0.45 11.0 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX72100.1 - 0.57 9.8 18.0 0.052 13.1 5.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 EAX72101.1 - 6.3e-53 177.3 20.2 3.9e-17 62.6 0.9 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX72101.1 - 1.1e-36 124.3 9.5 3.6e-11 43.1 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX72101.1 - 4.3e-36 122.8 6.6 2.2e-10 40.8 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX72101.1 - 1.7e-33 110.8 5.0 9.3e-07 28.7 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX72101.1 - 2.4e-33 113.1 4.5 4.7e-08 33.1 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat MetallophosN PF16371.5 EAX72101.1 - 1.3e-05 25.4 0.0 18 5.6 0.0 4.0 1 1 3 4 4 4 0 N terminal of Calcineurin-like phosphoesterase Arg_repressor PF01316.21 EAX72101.1 - 0.00061 19.5 0.2 30 4.5 0.0 4.0 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Stap_Strp_toxin PF01123.20 EAX72101.1 - 0.0046 17.8 3.8 4.3 8.3 0.1 3.6 1 1 2 3 3 3 2 Staphylococcal/Streptococcal toxin, OB-fold domain Glyco_hydro_20b PF02838.15 EAX72101.1 - 0.011 16.6 0.4 4 8.2 0.1 2.9 1 1 2 3 3 3 0 Glycosyl hydrolase family 20, domain 2 Phage_GPA PF05840.13 EAX72101.1 - 0.023 13.8 0.0 7.7 5.5 0.0 2.7 1 1 1 2 2 2 0 Bacteriophage replication gene A protein (GPA) DUF3718 PF12514.8 EAX72101.1 - 0.035 14.3 3.2 8 6.7 0.3 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3718) DUF348 PF03990.14 EAX72101.1 - 0.054 13.2 0.5 83 3.1 0.0 3.9 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain PTR PF12789.7 EAX72103.1 - 5.2e-61 202.6 43.6 1.7e-32 111.3 13.8 5.0 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX72103.1 - 0.037 13.7 0.9 0.081 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX72103.1 - 1.2 9.5 7.4 38 4.7 0.2 4.5 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF3839 PF12943.7 EAX72104.1 - 2.9e-158 524.6 14.6 3.6e-158 524.3 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX72104.1 - 0.1 13.0 0.4 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX72104.1 - 0.76 10.3 7.9 2.2 8.8 0.8 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX72105.1 - 3.1e-06 26.8 0.6 3.6e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX72105.1 - 0.036 14.4 0.6 0.036 14.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX72106.1 - 4.8e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX72106.1 - 0.0057 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX72106.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX72106.1 - 0.078 13.3 1.7 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2939 PF11159.8 EAX72107.1 - 0.0097 16.3 0.3 0.011 16.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX72108.1 - 0.0067 16.4 0.2 0.0097 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX72110.1 - 7.5e-61 204.2 8.2 8.4e-61 204.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX72110.1 - 0.1 12.8 0.1 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF563 PF04577.14 EAX72111.1 - 1.2e-17 64.7 0.0 1.9e-17 64.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF563) PAS_6 PF08348.11 EAX72111.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 YheO-like PAS domain PSP PF04046.16 EAX72112.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72113.1 - 0.081 13.5 5.7 11 7.2 0.2 3.4 3 1 1 4 4 4 0 TMP repeat PTR PF12789.7 EAX72114.1 - 2.6e-10 40.2 4.3 1.1e-08 35.0 0.4 4.3 5 0 0 5 5 5 2 Phage tail repeat like DUF5017 PF16409.5 EAX72114.1 - 0.013 14.9 1.5 0.46 9.9 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5017) YmaF PF12788.7 EAX72114.1 - 1.1 9.8 9.8 32 5.2 0.1 4.0 4 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX72114.1 - 2.6 7.6 9.9 0.73 9.4 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX72115.1 - 4e-132 430.4 99.3 3.1e-31 107.2 14.3 6.5 2 2 5 7 7 6 5 Phage tail repeat like HigB_toxin PF09907.9 EAX72115.1 - 0.00074 19.7 2.2 46 4.3 0.0 4.8 1 1 7 8 8 8 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Tis11B_N PF04553.12 EAX72115.1 - 0.0068 17.0 4.4 2.7 8.6 0.9 3.1 1 1 1 2 2 2 2 Tis11B like protein, N terminus DUF2785 PF10978.8 EAX72115.1 - 0.59 9.9 13.6 2.4 7.9 4.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF2785) KilA-N PF04383.13 EAX72119.1 - 2e-43 146.8 1.2 2.2e-43 146.7 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX72119.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) MPS2 PF17060.5 EAX72119.1 - 0.023 14.0 2.3 0.21 10.8 0.6 2.0 2 0 0 2 2 2 0 Monopolar spindle protein 2 T5orf172 PF10544.9 EAX72120.1 - 1.1e-06 29.0 0.2 2.3e-06 28.1 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Amidase02_C PF12123.8 EAX72121.1 - 0.034 13.8 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Nab1 PF04902.12 EAX72129.1 - 0.018 15.5 1.6 0.021 15.2 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 DUF3839 PF12943.7 EAX72130.1 - 4.2e-40 137.7 4.5 5.9e-40 137.2 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX72130.1 - 0.21 12.0 1.5 1.9 8.9 0.6 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4952 PF16310.5 EAX72132.1 - 0.055 13.7 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) DNA_pol_B_2 PF03175.13 EAX72135.1 - 3.5e-14 52.5 4.2 1.5e-13 50.5 4.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX72135.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Gly-zipper_Omp PF13488.6 EAX72136.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX72136.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX72136.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX72136.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX72136.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Trypan_PARP PF05887.11 EAX72137.1 - 0.12 12.3 12.0 0.13 12.2 12.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72137.1 - 0.83 10.1 5.7 0.95 9.9 5.7 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX72138.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX72139.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX72140.1 - 4.3e-75 252.3 7.9 5.4e-75 252.0 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FLYWCH PF04500.16 EAX72141.1 - 0.052 13.7 4.7 0.096 12.8 4.7 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX72141.1 - 0.072 13.8 1.0 0.18 12.5 1.0 1.7 1 1 0 1 1 1 0 FAR1 DNA-binding domain DDR PF08841.10 EAX72145.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX72145.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain IKKbetaNEMObind PF12179.8 EAX72146.1 - 0.097 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PAS_4 PF08448.10 EAX72146.1 - 0.1 12.9 0.0 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 PAS fold DUF4795 PF16043.5 EAX72147.1 - 6.2e-05 22.7 0.3 0.0001 22.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX72147.1 - 0.26 11.5 4.8 2.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX72148.1 - 5.2e-118 392.8 7.9 5.9e-118 392.6 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX72149.1 - 7.3e-23 80.6 0.5 9.8e-23 80.2 0.5 1.2 1 0 0 1 1 1 1 KilA-N domain EF-hand_7 PF13499.6 EAX72149.1 - 0.012 16.0 0.4 0.94 10.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Tox-GHH PF15636.6 EAX72149.1 - 0.028 14.4 0.0 0.073 13.1 0.0 1.8 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMP PF05017.14 EAX72150.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1031 PF06275.11 EAX72152.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX72152.1 - 0.096 12.8 0.3 0.53 10.4 0.2 2.2 1 1 1 2 2 2 0 Annexin GPS2_interact PF15784.5 EAX72154.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72154.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX72157.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX72157.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PTR PF12789.7 EAX72158.1 - 1.4e-57 191.6 32.0 1e-34 118.3 16.5 4.7 3 2 1 4 4 4 2 Phage tail repeat like T5orf172 PF10544.9 EAX72159.1 - 9.7e-07 29.3 0.3 1.9e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain RFX_DNA_binding PF02257.15 EAX72160.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX72160.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX72160.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF1493 PF07377.12 EAX72161.1 - 0.015 15.8 1.3 0.02 15.4 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF2939 PF11159.8 EAX72163.1 - 0.022 15.2 0.5 0.029 14.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72163.1 - 1.3 9.0 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX72164.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4106 PF13388.6 EAX72165.1 - 1e-209 697.0 22.8 1.9e-209 696.1 22.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.10 EAX72165.1 - 6.7 5.3 5.2 11 4.6 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_B_2 PF03175.13 EAX72166.1 - 1.7e-17 63.5 2.9 2e-17 63.3 2.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX72168.1 - 5.7e-10 38.7 3.1 2.9e-09 36.3 3.1 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72168.1 - 0.13 12.3 0.0 0.93 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX72168.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Mito_fiss_reg PF05308.11 EAX72169.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72169.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HTH_29 PF13551.6 EAX72170.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX72170.1 - 0.029 14.7 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Transposase Cas_Csm6 PF09659.10 EAX72171.1 - 0.0045 15.8 0.0 0.0058 15.5 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) DUF4795 PF16043.5 EAX72171.1 - 0.039 13.5 2.0 0.12 12.0 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX72171.1 - 0.94 9.6 18.2 0.15 12.1 2.7 4.2 4 1 0 4 4 4 0 Phage tail repeat like DNA_pol_B_2 PF03175.13 EAX72172.1 - 2.2e-09 36.7 1.1 6.8e-09 35.1 0.9 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72172.1 - 0.15 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX72173.1 - 5.9e-40 135.6 0.8 1e-39 134.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72173.1 - 0.04 14.5 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 Parathyroid hormone family DUF2939 PF11159.8 EAX72174.1 - 0.016 15.6 0.7 0.02 15.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) THF_DHG_CYH PF00763.23 EAX72174.1 - 0.094 13.0 3.4 0.12 12.7 3.4 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Membralin PF09746.9 EAX72174.1 - 2.5 7.1 3.8 2.5 7.1 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX72174.1 - 6.6 6.7 7.3 6.8 6.7 7.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DNA_pol_B_2 PF03175.13 EAX72175.1 - 1.9e-29 102.8 13.2 9.7e-29 100.5 13.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral UCH PF00443.29 EAX72176.1 - 0.0056 16.2 0.1 0.0056 16.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1493 PF07377.12 EAX72177.1 - 0.021 15.3 1.5 0.028 14.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX72178.1 - 0.01 15.9 0.4 0.015 15.3 0.4 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72179.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72179.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX72180.1 - 6e-154 510.5 12.8 7.5e-154 510.2 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX72180.1 - 0.15 12.4 2.7 14 6.1 0.0 3.6 4 1 0 4 4 4 0 Tup N-terminal NTP_transf_6 PF06042.11 EAX72180.1 - 0.15 11.9 1.2 0.51 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX72180.1 - 0.26 11.8 3.7 0.74 10.3 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX72181.1 - 2.6e-231 768.1 47.4 6.9e-154 513.1 22.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX72181.1 - 0.0056 17.0 0.1 0.21 11.9 0.3 2.2 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX72181.1 - 0.024 14.5 0.2 0.053 13.3 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Caprin-1_dimer PF18293.1 EAX72181.1 - 0.077 13.5 0.5 0.18 12.3 0.5 1.7 1 0 0 1 1 1 0 Caprin-1 dimerization domain GGN PF15685.5 EAX72181.1 - 0.75 8.8 33.4 1 8.3 33.4 1.1 1 0 0 1 1 1 0 Gametogenetin GPS2_interact PF15784.5 EAX72182.1 - 0.05 14.0 1.3 0.067 13.6 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72182.1 - 0.14 11.1 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72183.1 - 0.076 13.0 13.2 0.078 13.0 13.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72183.1 - 4.5 7.7 8.2 5.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GCD14 PF08704.10 EAX72184.1 - 9.1 5.9 7.8 1.2 8.7 2.4 1.9 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit KilA-N PF04383.13 EAX72186.1 - 9.1e-42 141.4 0.1 1.3e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF4107 PF13389.6 EAX72187.1 - 1e-72 243.6 4.2 1.3e-72 243.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX72187.1 - 0.18 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Beta_helix PF13229.6 EAX72189.1 - 0.002 18.0 9.0 0.06 13.2 0.2 2.5 2 0 0 2 2 2 2 Right handed beta helix region DUF3839 PF12943.7 EAX72190.1 - 2.7e-135 449.4 10.7 3.1e-135 449.2 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72190.1 - 0.024 15.1 1.9 1.2 9.6 0.4 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ComA PF02679.15 EAX72191.1 - 0.037 13.5 0.4 0.04 13.4 0.4 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX72191.1 - 0.2 11.1 0.3 0.34 10.3 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF4107 PF13389.6 EAX72192.1 - 7.8e-62 208.2 12.2 4.4e-60 202.5 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72192.1 - 0.11 12.9 0.5 0.14 12.5 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX72193.1 - 4.1e-10 39.6 9.3 1.1e-08 35.1 5.6 4.3 5 0 0 5 5 5 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX72193.1 - 0.071 13.3 0.0 8.2 6.7 0.0 2.3 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain EpuA PF11772.8 EAX72193.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta IL2 PF00715.17 EAX72193.1 - 0.2 11.6 3.4 5.6 6.9 0.1 2.8 2 1 1 3 3 3 0 Interleukin 2 EMP24_GP25L PF01105.24 EAX72193.1 - 1.3 8.9 5.2 24 4.8 1.2 3.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF5082 PF16888.5 EAX72193.1 - 5.9 7.2 8.2 4.4 7.6 2.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Spo12 PF05032.12 EAX72194.1 - 0.48 10.4 8.0 0.16 11.9 2.9 2.2 2 0 0 2 2 2 0 Spo12 family DUF4108 PF13390.6 EAX72196.1 - 3e-51 173.1 5.6 3.3e-51 173.0 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX72199.1 - 8.2e-61 204.1 7.9 9.1e-61 204.0 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX72201.1 - 1.6e-50 171.4 1.2 1.9e-50 171.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX72202.1 - 4.8e-157 520.6 14.7 5.7e-157 520.4 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72202.1 - 0.1 13.0 2.1 0.21 12.0 0.3 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX72202.1 - 0.15 11.9 1.3 0.54 10.1 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX72202.1 - 0.96 10.0 8.0 2.1 8.8 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX72203.1 - 4.1e-26 91.9 3.9 5.8e-26 91.4 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX72203.1 - 0.054 13.8 0.4 0.19 12.0 0.0 2.0 1 1 1 2 2 2 0 PRD domain DUF3839 PF12943.7 EAX72204.1 - 2.1e-94 315.5 9.1 2.4e-94 315.3 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX72204.1 - 0.072 13.7 0.8 0.31 11.7 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5398) PTR PF12789.7 EAX72205.1 - 8.1e-77 253.2 54.0 7.9e-32 109.1 14.4 4.9 2 2 3 5 5 4 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX72205.1 - 0.017 15.0 0.7 0.034 14.0 0.7 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX72205.1 - 0.035 13.8 1.0 0.065 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX72205.1 - 0.22 11.0 5.9 0.53 9.7 0.7 2.3 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF2939 PF11159.8 EAX72206.1 - 0.017 15.5 0.4 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72206.1 - 1.6 8.8 5.4 1.7 8.7 5.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX72207.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Csm1_N PF18504.1 EAX72208.1 - 0.00019 21.7 4.4 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX72208.1 - 0.00068 19.7 9.1 0.0033 17.5 9.2 1.9 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 EAX72208.1 - 0.0027 18.1 3.7 0.0044 17.4 3.7 1.4 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX72208.1 - 0.0041 16.1 4.7 0.0047 15.9 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX72208.1 - 0.0054 16.5 5.5 0.0072 16.2 1.4 2.9 1 1 2 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX72208.1 - 0.0063 16.8 4.0 0.0095 16.3 4.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 EAX72208.1 - 0.013 15.7 6.2 0.016 15.4 6.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EAX72208.1 - 0.013 15.4 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HemX PF04375.14 EAX72208.1 - 0.018 14.4 4.0 0.022 14.0 4.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 EAX72208.1 - 0.025 13.7 3.8 0.025 13.7 3.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EAX72208.1 - 0.027 14.5 7.4 0.043 13.9 7.2 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 EAX72208.1 - 0.028 13.8 4.9 0.033 13.5 4.9 1.1 1 0 0 1 1 1 0 FAM76 protein GNT-I PF03071.15 EAX72208.1 - 0.043 12.6 0.9 0.058 12.2 0.9 1.1 1 0 0 1 1 1 0 GNT-I family ATG16 PF08614.11 EAX72208.1 - 0.083 13.1 10.7 0.11 12.7 10.7 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EAX72208.1 - 0.092 12.5 7.4 1.2 8.9 4.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 EAX72208.1 - 0.11 11.8 3.2 0.13 11.5 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 EAX72208.1 - 0.49 10.5 6.6 31 4.8 0.0 2.5 1 1 0 2 2 2 0 bZIP transcription factor COMP PF11598.8 EAX72208.1 - 0.98 9.9 5.8 2.3 8.7 3.1 2.2 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 EAX72208.1 - 2.2 8.1 8.5 2 8.2 3.6 2.2 1 1 1 2 2 2 0 Septum formation initiator PTR PF12789.7 EAX72209.1 - 3.1e-47 158.5 32.0 4.5e-32 109.9 15.8 3.6 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX72209.1 - 0.032 13.9 0.9 0.074 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX72210.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX72212.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72212.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal T5orf172 PF10544.9 EAX72213.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX72215.1 - 2.1e-72 242.6 3.8 2.8e-72 242.2 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX72216.1 - 2e-229 761.9 19.2 2.3e-229 761.7 19.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX72216.1 - 0.01 16.1 0.1 0.52 10.6 0.1 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated DUF1043 PF06295.12 EAX72218.1 - 0.074 13.1 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX72218.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX72219.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72219.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX72220.1 - 3.4e-53 179.4 5.8 3.7e-53 179.3 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX72221.1 - 3.4e-36 123.5 0.1 5.2e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX72221.1 - 0.024 14.8 0.1 0.062 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX72221.1 - 0.32 11.5 8.9 1.6 9.2 3.3 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3839 PF12943.7 EAX72222.1 - 1.1e-141 470.4 10.8 1.3e-141 470.1 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX72222.1 - 0.29 11.6 2.4 4.8 7.7 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF2408 PF10303.9 EAX72222.1 - 0.36 11.4 3.3 0.41 11.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX72222.1 - 1.1 9.8 8.5 4.2 7.9 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX72223.1 - 5e-15 55.3 0.2 9.1e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72223.1 - 0.044 13.8 0.4 0.32 11.0 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pox_A32 PF04665.12 EAX72225.1 - 4.3e-06 26.4 2.8 6.1e-06 25.9 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72225.1 - 0.0045 16.7 0.2 0.0058 16.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72225.1 - 0.054 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72225.1 - 0.059 13.1 0.3 0.25 11.1 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72225.1 - 0.088 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72225.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72225.1 - 0.58 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF2897 PF11446.8 EAX72226.1 - 0.36 10.8 2.6 0.78 9.7 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX72227.1 - 3.2e-53 179.5 7.8 3.6e-53 179.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX72228.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72228.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAS_N PF17828.1 EAX72229.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX72229.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF3839 PF12943.7 EAX72230.1 - 6.8e-155 513.6 11.6 7.7e-155 513.4 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX72230.1 - 0.072 13.4 0.6 1.9 8.8 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX72230.1 - 0.19 12.2 6.8 1.5 9.3 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX72230.1 - 0.66 10.3 4.4 11 6.4 0.1 3.4 3 2 1 4 4 4 0 Tup N-terminal FAS_N PF17828.1 EAX72232.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72233.1 - 0.013 15.9 0.3 0.015 15.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4795 PF16043.5 EAX72235.1 - 0.0021 17.7 21.8 0.91 9.1 2.5 4.3 1 1 3 4 4 4 4 Domain of unknown function (DUF4795) AltA1 PF16541.5 EAX72235.1 - 0.058 14.3 3.7 27 5.7 0.1 3.6 1 1 2 3 3 3 0 Alternaria alternata allergen 1 DNA_meth_N PF18284.1 EAX72235.1 - 0.074 13.0 2.4 40 4.2 0.1 3.4 2 1 1 3 3 3 0 DNA methylase N-terminal domain EpuA PF11772.8 EAX72235.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TetR_C_26 PF17934.1 EAX72235.1 - 0.32 11.3 2.1 6.2 7.2 0.3 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Hep_59 PF07052.11 EAX72235.1 - 1.5 9.6 4.9 1.3e+02 3.3 4.9 3.0 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Topo_Zn_Ribbon PF08272.11 EAX72235.1 - 1.7 8.4 8.4 29 4.4 0.0 4.5 4 1 1 5 5 5 0 Topoisomerase I zinc-ribbon-like Phage_fiber PF03335.13 EAX72235.1 - 1.9 8.9 9.8 0.45 10.8 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat PSP PF04046.16 EAX72236.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72237.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72238.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72239.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX72240.1 - 0.00019 21.8 2.3 0.0011 19.5 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX72241.1 - 2.2e-63 212.4 6.7 2.5e-63 212.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2593 PF10767.9 EAX72242.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Pox_A32 PF04665.12 EAX72243.1 - 6.8e-07 29.0 2.4 6.8e-07 29.0 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72243.1 - 3.9e-05 23.5 0.3 0.37 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72243.1 - 4.3e-05 23.8 0.2 0.00032 21.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72243.1 - 0.00028 20.9 4.2 0.00048 20.2 3.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72243.1 - 0.00079 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72243.1 - 0.0036 17.1 0.7 0.0036 17.1 0.7 1.9 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 EAX72243.1 - 0.007 16.0 3.2 0.014 15.0 0.5 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72243.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72243.1 - 0.091 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX72243.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72243.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX72243.1 - 0.13 12.3 1.0 1.9 8.5 1.0 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX72243.1 - 0.36 11.5 12.7 0.14 12.9 2.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX72243.1 - 0.57 10.5 4.1 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Mer2 PF09074.10 EAX72244.1 - 0.55 10.0 9.4 0.63 9.8 8.7 1.4 1 1 1 2 2 2 0 Mer2 Fibritin_C PF07921.12 EAX72244.1 - 7.2 6.8 16.3 23 5.2 0.1 3.7 1 1 1 3 3 3 0 Fibritin C-terminal region DUF1493 PF07377.12 EAX72245.1 - 0.04 14.4 0.4 0.077 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX72246.1 - 0.042 14.4 3.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX72247.1 - 1.2e-06 28.3 0.9 1.9e-06 27.7 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain DUF4543 PF15076.6 EAX72247.1 - 0.062 13.4 0.2 0.15 12.2 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) EssA PF10661.9 EAX72247.1 - 4.4 7.1 8.4 12 5.7 8.3 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX72248.1 - 6.7e-117 389.2 6.6 7.5e-117 389.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX72248.1 - 2.3 8.5 4.3 10 6.5 0.1 3.0 2 1 1 3 3 3 0 Rx N-terminal domain FAS_N PF17828.1 EAX72249.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72250.1 - 0.026 14.9 1.0 0.033 14.6 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX72250.1 - 2.6 7.0 6.2 2.6 7.0 6.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF3839 PF12943.7 EAX72251.1 - 4.3e-25 88.6 5.0 6.2e-25 88.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX72251.1 - 0.13 11.4 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DNA_pol_B_2 PF03175.13 EAX72252.1 - 9.4e-27 94.0 10.5 3.2e-26 92.2 10.5 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72252.1 - 0.097 12.7 0.0 0.92 9.5 0.0 2.5 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX72253.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72253.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX72255.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72255.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72255.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72255.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72255.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72255.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72255.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72255.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72255.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72255.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72255.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72255.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MULE PF10551.9 EAX72256.1 - 0.021 15.2 1.2 0.13 12.7 0.1 2.8 2 1 0 3 3 3 0 MULE transposase domain DUF2960 PF11173.8 EAX72256.1 - 0.043 14.3 0.3 0.11 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Pox_A32 PF04665.12 EAX72257.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72257.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72257.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72257.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX72258.1 - 6.6e-07 29.0 2.3 6.6e-07 29.0 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72258.1 - 3.8e-05 23.5 0.3 0.35 10.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72258.1 - 4.2e-05 23.8 0.2 0.00032 21.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72258.1 - 0.00048 20.2 4.9 0.00091 19.3 4.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72258.1 - 0.00079 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72258.1 - 0.0034 17.2 0.7 0.0034 17.2 0.7 1.9 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 EAX72258.1 - 0.007 16.0 3.2 0.014 15.0 0.5 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72258.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72258.1 - 0.09 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX72258.1 - 0.1 13.0 0.1 0.93 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72258.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX72258.1 - 0.13 12.3 1.0 1.9 8.5 1.0 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX72258.1 - 0.33 11.6 12.5 0.14 12.9 2.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX72258.1 - 0.56 10.5 4.1 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX72259.1 - 7.9e-154 510.1 12.1 9.5e-154 509.8 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72259.1 - 0.088 13.3 4.5 0.53 10.8 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX72259.1 - 0.09 13.1 1.9 11 6.5 0.0 3.2 3 1 1 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX72260.1 - 1.1e-06 29.1 0.1 2.6e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72260.1 - 0.0041 17.0 1.2 0.028 14.2 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX72260.1 - 0.11 12.0 0.6 0.3 10.6 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain FAS_N PF17828.1 EAX72261.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72262.1 - 0.0042 17.5 0.7 0.005 17.2 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72262.1 - 3.4 7.6 6.9 3.7 7.5 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_D5 PF03288.16 EAX72263.1 - 0.0001 22.7 2.5 0.00064 20.2 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72263.1 - 0.089 13.4 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3839 PF12943.7 EAX72265.1 - 4.3e-68 229.4 2.1 5.4e-68 229.0 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX72267.1 - 6.5e-80 268.1 11.7 8.7e-80 267.7 11.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72267.1 - 0.069 12.7 0.4 0.24 10.9 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 DUF2939 PF11159.8 EAX72268.1 - 0.025 15.0 0.3 0.034 14.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72268.1 - 2.2 8.3 4.8 2.4 8.2 4.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX72269.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Apolipoprotein PF01442.18 EAX72270.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3839 PF12943.7 EAX72271.1 - 6.6e-121 402.3 11.2 8.2e-121 402.0 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72271.1 - 0.14 11.7 0.7 0.64 9.5 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 Pox_D5 PF03288.16 EAX72272.1 - 1.1e-05 25.9 2.5 6e-05 23.5 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72272.1 - 0.064 13.9 0.1 0.11 13.2 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX72272.1 - 0.13 12.3 0.3 0.23 11.4 0.2 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX72273.1 - 2.4e-54 183.1 8.4 2.7e-54 183.0 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GH97_C PF14509.6 EAX72273.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation GGDEF PF00990.21 EAX72274.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Ly49 PF08391.10 EAX72274.1 - 0.84 10.0 3.8 1.1 9.7 3.8 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX72274.1 - 2.8 7.9 5.9 5.8 6.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX72275.1 - 4.4e-10 39.0 0.9 9.2e-10 38.0 0.9 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX72276.1 - 0.042 14.3 1.2 0.057 13.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX72276.1 - 0.23 11.6 3.4 6.1 7.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX72277.1 - 3.8e-07 29.8 3.1 4e-07 29.7 1.5 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72277.1 - 3.9e-05 23.4 0.3 0.39 10.4 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72277.1 - 7.8e-05 23.0 0.2 0.00052 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72277.1 - 0.00015 21.9 3.4 0.00026 21.0 2.9 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72277.1 - 0.00062 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72277.1 - 0.0019 18.1 0.5 0.0035 17.2 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72277.1 - 0.0025 17.5 0.5 0.016 14.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72277.1 - 0.016 15.5 0.0 0.052 13.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX72277.1 - 0.059 12.9 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX72277.1 - 0.08 12.4 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX72277.1 - 0.085 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX72277.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX72277.1 - 0.11 12.9 0.0 0.64 10.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX72277.1 - 0.31 11.3 3.4 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Myb_DNA-binding PF00249.31 EAX72278.1 - 5.2e-24 84.2 4.4 2.1e-11 43.8 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX72278.1 - 1.7e-16 60.2 0.6 1.1e-09 38.4 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EAX72278.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX72278.1 - 0.15 12.4 1.9 3.1 8.2 0.6 3.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain KilA-N PF04383.13 EAX72280.1 - 7.2e-17 61.3 1.2 1.2e-16 60.6 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX72280.1 - 0.0039 17.3 0.1 0.0098 16.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF3819 PF12842.7 EAX72281.1 - 0.064 13.2 4.4 0.074 13.0 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) TCO89 PF10452.9 EAX72281.1 - 2.8 6.8 12.2 3 6.7 12.2 1.0 1 0 0 1 1 1 0 TORC1 subunit TCO89 DUF1493 PF07377.12 EAX72282.1 - 0.043 14.3 0.3 0.1 13.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX72283.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72284.1 - 0.09 13.4 5.4 11 7.3 0.2 3.3 3 1 1 4 4 4 0 TMP repeat DUF2939 PF11159.8 EAX72286.1 - 0.016 15.6 0.4 0.022 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX72287.1 - 0.034 14.0 0.0 0.084 12.8 0.0 1.6 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain AAA_22 PF13401.6 EAX72288.1 - 2.3e-05 24.7 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72288.1 - 3.3e-05 23.7 0.3 0.38 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX72288.1 - 4.5e-05 23.0 2.0 4.5e-05 23.0 2.0 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX72288.1 - 0.00013 22.0 3.5 0.00027 21.0 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72288.1 - 0.00044 20.1 0.1 0.0008 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX72288.1 - 0.0013 18.4 0.4 0.01 15.5 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX72288.1 - 0.0015 18.4 0.9 0.0041 16.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72288.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72288.1 - 0.049 13.2 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72288.1 - 0.059 13.8 0.1 0.54 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX72288.1 - 0.062 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX72288.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX72288.1 - 0.24 11.4 2.2 1.5 8.8 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX72288.1 - 0.31 11.3 4.8 6.4 7.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) YfbU PF03887.14 EAX72291.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 YfbU domain Antimicrobial_8 PF08103.11 EAX72291.1 - 8.2 6.8 6.3 1.5 9.2 0.6 2.6 2 0 0 2 2 2 0 Uperin family Pox_A32 PF04665.12 EAX72294.1 - 4.1e-05 23.2 2.6 4.1e-05 23.2 2.6 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX72294.1 - 0.0025 17.8 1.4 0.007 16.4 0.2 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX72294.1 - 0.0091 15.6 0.3 0.02 14.5 0.3 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX72294.1 - 0.046 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX72294.1 - 0.11 12.8 3.1 0.15 12.4 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) T5orf172 PF10544.9 EAX72295.1 - 1.2e-06 29.0 0.2 4.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 T5orf172 domain Pox_D5 PF03288.16 EAX72296.1 - 4.3e-05 23.9 3.6 0.00033 21.1 3.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72296.1 - 0.03 14.9 0.1 0.055 14.1 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX72296.1 - 0.073 13.1 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX72297.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX72299.1 - 5.6e-27 93.8 0.8 1.1e-26 92.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72299.1 - 0.02 15.5 0.0 0.054 14.1 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX72300.1 - 3.8e-155 514.4 12.8 4.8e-155 514.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72300.1 - 0.19 11.6 1.3 0.58 10.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX72300.1 - 0.37 11.1 4.5 1.1 9.7 0.1 3.2 3 1 0 3 3 3 0 PRD domain KELK PF15796.5 EAX72300.1 - 0.75 10.3 5.2 1.7 9.1 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX72301.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72302.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX72303.1 - 2.2e-64 215.7 5.6 2.5e-64 215.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72304.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX72305.1 - 6.1e-127 422.1 5.9 6.9e-127 421.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX72305.1 - 0.054 13.0 0.5 0.095 12.2 0.3 1.4 1 1 0 1 1 1 0 Z1 domain Mito_fiss_reg PF05308.11 EAX72307.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72307.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_A32 PF04665.12 EAX72310.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72310.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72310.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72310.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 EAX72311.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4108 PF13390.6 EAX72313.1 - 5e-63 211.3 5.7 5.6e-63 211.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX72315.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX72315.1 - 0.081 12.9 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF4107 PF13389.6 EAX72316.1 - 9e-52 175.5 1.3 1.4e-51 174.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FAS_N PF17828.1 EAX72317.1 - 0.016 15.2 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Peptidase_C3G PF12381.8 EAX72317.1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase DUF2939 PF11159.8 EAX72318.1 - 0.017 15.5 0.5 0.021 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72318.1 - 1.4 8.9 5.8 1.5 8.8 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX72318.1 - 1.5 7.8 2.7 1.6 7.7 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TMP PF05017.14 EAX72319.1 - 0.14 12.8 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72320.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP VirE PF05272.11 EAX72321.1 - 0.00053 19.8 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX72321.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX72321.1 - 0.12 11.3 0.2 10 4.9 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PadR PF03551.14 EAX72322.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MULE PF10551.9 EAX72324.1 - 4.9e-08 33.3 0.0 9.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF4108 PF13390.6 EAX72325.1 - 9.2e-70 233.1 12.4 1.1e-69 232.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX72326.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72327.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RFX_DNA_binding PF02257.15 EAX72329.1 - 0.00015 22.3 0.2 0.00022 21.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX72329.1 - 0.00061 20.2 1.7 0.00093 19.6 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX72329.1 - 0.032 14.2 0.1 0.069 13.1 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX72330.1 - 2.4e-62 209.1 5.0 2.7e-62 208.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX72331.1 - 3.5e-231 767.7 16.1 5.6e-231 767.0 16.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX72331.1 - 0.00041 20.6 0.2 0.021 15.1 0.3 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated DNA_pol_B_2 PF03175.13 EAX72332.1 - 1.1e-24 87.2 7.8 4.2e-24 85.2 7.8 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72332.1 - 0.11 12.5 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX72332.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 GPS2_interact PF15784.5 EAX72333.1 - 0.039 14.4 1.5 0.053 14.0 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72333.1 - 0.044 12.8 0.1 0.045 12.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72334.1 - 0.032 14.2 8.7 0.05 13.6 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72334.1 - 6.6 7.2 6.1 9.5 6.7 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX72335.1 - 3e-79 265.9 10.2 4e-79 265.5 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72335.1 - 0.025 15.1 0.4 0.03 14.8 0.4 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX72335.1 - 0.071 13.7 0.7 0.12 12.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) YvrJ PF12841.7 EAX72336.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family HC2 PF07382.11 EAX72337.1 - 3.2e-08 33.9 11.0 3.5e-08 33.8 11.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX72337.1 - 8.9e-05 22.6 1.6 0.00011 22.2 1.6 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) XAP5 PF04921.14 EAX72337.1 - 0.42 10.4 4.7 0.57 10.0 4.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Aurora-A_bind PF09041.10 EAX72337.1 - 2 8.6 8.5 3.2e+02 1.5 8.5 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX72337.1 - 3 7.9 5.1 1e+02 3.0 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) FliD_N PF02465.18 EAX72338.1 - 0.33 11.7 5.2 0.5 11.1 5.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX72338.1 - 1.5 7.5 3.9 1.9 7.2 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3839 PF12943.7 EAX72339.1 - 7.5e-119 395.6 11.4 9.4e-119 395.2 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX72339.1 - 0.038 14.2 0.1 0.099 12.9 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 KELK PF15796.5 EAX72339.1 - 0.21 12.1 3.2 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX72341.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX72341.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DDE_1 PF03184.19 EAX72342.1 - 3.5e-14 52.9 0.0 5.6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PMC2NT PF08066.12 EAX72342.1 - 0.081 13.6 0.1 0.28 11.9 0.1 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain AAA_22 PF13401.6 EAX72344.1 - 2e-05 24.9 0.2 0.00015 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72344.1 - 2.4e-05 24.1 0.3 0.26 11.0 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX72344.1 - 2.7e-05 23.7 2.1 2.7e-05 23.7 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX72344.1 - 0.00011 22.2 3.1 0.00023 21.2 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72344.1 - 0.00038 20.3 0.1 0.00072 19.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX72344.1 - 0.001 18.8 0.4 0.0073 16.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX72344.1 - 0.0012 18.7 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72344.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72344.1 - 0.048 13.2 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX72344.1 - 0.052 13.0 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX72344.1 - 0.062 13.7 0.1 0.55 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72344.1 - 0.071 12.6 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72344.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX72344.1 - 0.32 11.3 4.5 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX72347.1 - 1.1e-18 67.0 0.1 1.5e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72347.1 - 0.077 13.0 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pox_A32 PF04665.12 EAX72349.1 - 4.1e-07 29.7 1.9 5.7e-07 29.2 1.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72349.1 - 0.049 13.3 0.2 0.061 13.0 0.2 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX72349.1 - 0.065 13.0 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX72349.1 - 0.11 12.2 0.2 0.51 10.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72349.1 - 0.23 11.4 2.2 1.6 8.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX72350.1 - 2.2e-07 30.6 0.5 1.5e-06 27.8 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX72350.1 - 0.048 13.8 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX72350.1 - 0.063 12.9 0.1 1.4 8.5 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72350.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase Pox_A32 PF04665.12 EAX72351.1 - 4.1e-07 29.7 0.4 3.1e-06 26.8 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein TK PF00265.18 EAX72351.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72351.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX72352.1 - 1.1e-118 395.1 11.6 1.4e-118 394.7 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72352.1 - 0.11 12.4 0.5 0.21 11.4 0.3 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase PRD PF00874.20 EAX72352.1 - 1.1 9.6 0.1 1.1 9.6 0.1 2.9 4 0 0 4 4 4 0 PRD domain GPS2_interact PF15784.5 EAX72353.1 - 0.019 15.4 0.4 0.023 15.1 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72353.1 - 0.12 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72354.1 - 0.11 12.5 7.1 0.17 11.8 7.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX72358.1 - 5.4e-157 520.5 15.6 6.8e-157 520.1 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72358.1 - 0.16 11.5 0.5 0.46 10.0 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 KELK PF15796.5 EAX72358.1 - 2.2 8.8 8.1 4 7.9 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX72359.1 - 0.021 14.8 8.5 0.028 14.4 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72359.1 - 3.2 8.2 4.9 4 7.9 4.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX72360.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72360.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX72361.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) LRR_5 PF13306.6 EAX72363.1 - 1.3e-67 225.6 40.5 2.9e-30 104.8 12.6 3.3 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX72363.1 - 1.5e-15 56.7 1.1 0.00055 19.7 0.5 5.6 3 2 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EAX72363.1 - 0.037 14.5 13.0 15 6.1 2.0 5.5 5 2 1 7 7 7 0 Leucine Rich repeats (2 copies) DUF4108 PF13390.6 EAX72364.1 - 3.5e-63 211.8 6.3 3.9e-63 211.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72365.1 - 2 8.4 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Tcf25 PF04910.14 EAX72366.1 - 0.082 12.0 0.2 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DUF4795 PF16043.5 EAX72366.1 - 0.25 10.9 10.1 0.32 10.6 4.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX72366.1 - 1 9.4 8.2 0.17 12.0 2.1 3.0 3 1 0 3 3 3 0 Phage tail repeat like Phage_fiber PF03335.13 EAX72366.1 - 4.6 7.7 7.0 5.3 7.5 1.1 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat KilA-N PF04383.13 EAX72367.1 - 8.1e-41 138.4 1.7 8.5e-41 138.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72367.1 - 0.0065 17.1 0.7 0.016 15.8 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX72368.1 - 5.9e-07 29.2 2.6 5.9e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72368.1 - 3e-05 24.3 0.2 0.00022 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72368.1 - 6e-05 22.9 0.2 0.38 10.5 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72368.1 - 0.00012 22.1 2.9 0.0003 20.8 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72368.1 - 0.00052 19.8 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72368.1 - 0.0015 18.4 0.5 0.0026 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72368.1 - 0.002 17.8 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72368.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72368.1 - 0.061 12.9 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX72368.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX72368.1 - 0.11 12.9 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX72368.1 - 0.51 10.6 3.4 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX72369.1 - 2.8e-23 81.7 8.9 2.8e-23 81.7 8.9 4.0 2 2 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX72369.1 - 0.03 14.1 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX72369.1 - 0.15 12.0 5.1 1 9.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Trypan_PARP PF05887.11 EAX72370.1 - 0.14 12.1 12.0 0.23 11.4 12.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX72372.1 - 1.3e-136 453.7 14.7 1.5e-136 453.5 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72372.1 - 0.06 13.2 0.7 0.19 11.6 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX72372.1 - 0.076 13.3 4.6 0.21 11.9 0.1 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX72372.1 - 0.43 11.1 6.9 1.5 9.3 1.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ArsA_ATPase PF02374.15 EAX72372.1 - 1.8 7.7 6.0 0.71 9.0 0.6 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase Pox_D5 PF03288.16 EAX72373.1 - 7.7e-05 23.1 2.5 0.00036 21.0 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX72373.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX72375.1 - 4.4e-57 193.3 3.1 4.8e-57 193.2 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX72375.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.0 1 0 0 1 1 1 0 Z1 domain Pox_A32 PF04665.12 EAX72376.1 - 1.8e-07 30.9 2.2 2.2e-07 30.6 2.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72376.1 - 0.0038 16.9 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72376.1 - 0.04 13.4 0.1 0.052 13.0 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72376.1 - 0.056 13.2 0.2 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72376.1 - 0.073 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72376.1 - 0.17 11.9 2.0 1.2 9.2 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72376.1 - 0.33 11.2 8.6 4.9 7.4 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX72377.1 - 8.7e-25 87.5 6.2 1.6e-24 86.6 6.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX72377.1 - 0.036 14.1 1.2 0.76 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) FAS_N PF17828.1 EAX72378.1 - 0.016 15.2 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Peptidase_C3G PF12381.8 EAX72378.1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase Amidase02_C PF12123.8 EAX72380.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX72381.1 - 1.6e-42 145.4 1.0 1.8e-42 145.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72381.1 - 0.063 13.6 0.2 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4106 PF13388.6 EAX72382.1 - 1.9e-187 623.6 24.4 2.8e-187 623.1 24.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX72382.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DDE_1 PF03184.19 EAX72383.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KilA-N PF04383.13 EAX72385.1 - 1.5e-41 140.7 1.2 2.5e-41 140.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX72385.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Gly-zipper_Omp PF13488.6 EAX72386.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX72386.1 - 0.51 10.7 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF4108 PF13390.6 EAX72388.1 - 8.3e-41 139.3 0.6 9.2e-41 139.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FAS_N PF17828.1 EAX72389.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF257 PF03192.13 EAX72390.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX72390.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Phage_P2_GpE PF06528.12 EAX72391.1 - 1e-06 28.1 0.2 1.7e+02 1.9 0.0 8.7 10 0 0 10 10 10 0 Phage P2 GpE Kelch_1 PF01344.25 EAX72391.1 - 4.2e-06 26.2 0.8 1.4e+02 2.1 0.0 7.3 8 0 0 8 8 8 0 Kelch motif Kelch_1 PF01344.25 EAX72392.1 - 8.4e-05 22.1 0.3 53 3.5 0.0 5.6 5 1 0 5 5 5 0 Kelch motif DUF5438 PF17506.2 EAX72392.1 - 0.04 14.2 20.2 4.6 7.6 0.6 5.9 1 1 5 6 6 6 0 Family of unknown function (DUF5438) Phage_P2_GpE PF06528.12 EAX72392.1 - 0.24 11.0 3.9 1.4e+02 2.2 0.0 4.6 6 0 0 6 6 6 0 Phage P2 GpE Thoc2 PF11732.8 EAX72392.1 - 0.9 9.7 10.3 1.2 9.3 2.7 3.2 1 1 1 2 2 2 0 Transcription- and export-related complex subunit Pox_A32 PF04665.12 EAX72393.1 - 4.5e-07 29.6 2.6 4.5e-07 29.6 2.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72393.1 - 3.8e-05 23.5 0.3 0.36 10.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72393.1 - 4.5e-05 23.7 0.2 0.00033 20.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72393.1 - 0.00036 20.6 4.4 0.00075 19.5 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72393.1 - 0.00079 19.2 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72393.1 - 0.0018 18.2 1.1 0.0029 17.5 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72393.1 - 0.0046 16.6 3.0 0.012 15.3 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72393.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain TPK_catalytic PF04263.16 EAX72393.1 - 0.083 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX72393.1 - 0.091 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX72393.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72393.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72393.1 - 0.49 10.7 4.1 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX72393.1 - 0.75 10.5 11.8 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 FAS_N PF17828.1 EAX72394.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX72394.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX72395.1 - 0.002 18.5 0.3 0.0026 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX72395.1 - 0.09 12.7 0.1 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX72395.1 - 1.5 8.8 5.0 1.6 8.7 5.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX72397.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72397.1 - 0.18 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family JMY PF15871.5 EAX72399.1 - 0.035 13.4 0.3 0.053 12.8 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX72399.1 - 0.091 12.8 3.4 0.74 9.9 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) TMP PF05017.14 EAX72400.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX72401.1 - 0.03 14.8 0.9 0.067 13.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FliJ PF02050.16 EAX72402.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Trypan_PARP PF05887.11 EAX72404.1 - 0.068 13.2 7.2 0.088 12.8 7.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72404.1 - 9.2 6.7 6.0 12 6.4 6.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX72405.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72405.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX72407.1 - 9.7e-25 87.4 7.1 6.3e-24 84.7 7.1 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72407.1 - 0.038 14.0 0.1 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX72407.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF2939 PF11159.8 EAX72408.1 - 0.015 15.7 0.4 0.017 15.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PTR PF12789.7 EAX72409.1 - 9.1e-30 102.5 11.5 9.1e-30 102.5 11.5 3.0 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX72409.1 - 0.037 12.9 0.3 0.74 8.6 0.0 2.1 2 0 0 2 2 2 0 BRO1-like domain YmaF PF12788.7 EAX72409.1 - 1.2 9.8 9.6 39 4.9 0.1 3.0 2 1 0 2 2 2 0 YmaF family DUF240 PF03086.14 EAX72409.1 - 3.3 7.7 8.4 1.9 8.4 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) TPR_MLP1_2 PF07926.12 EAX72410.1 - 0.014 15.5 0.2 0.017 15.2 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX72410.1 - 0.061 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX72410.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family rve PF00665.26 EAX72411.1 - 3.7e-17 62.6 0.1 1e-16 61.2 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX72411.1 - 2.5e-05 24.5 0.1 6.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 EAX72411.1 - 0.014 15.1 0.4 0.14 12.0 0.4 2.5 1 1 0 1 1 1 0 Integrase core domain FAS_N PF17828.1 EAX72412.1 - 0.0022 18.0 0.1 0.0032 17.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Phage_CP76 PF06892.11 EAX72413.1 - 0.61 9.6 10.4 17 4.9 0.5 3.3 1 1 1 2 2 2 0 Phage regulatory protein CII (CP76) PTR PF12789.7 EAX72414.1 - 9.7e-110 358.7 76.5 6.7e-35 119.0 16.4 5.3 3 3 4 7 7 6 4 Phage tail repeat like DUF4116 PF13475.6 EAX72414.1 - 0.037 13.7 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX72415.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX72417.1 - 0.0094 16.0 0.3 0.012 15.7 0.3 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Csm2_III-A PF03750.13 EAX72417.1 - 0.036 14.9 1.7 0.043 14.6 1.7 1.1 1 0 0 1 1 1 0 Csm2 Type III-A PaRep2a PF07903.11 EAX72417.1 - 0.038 13.8 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Amidase02_C PF12123.8 EAX72420.1 - 0.0019 17.8 0.0 0.0056 16.4 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX72420.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TPR_MLP1_2 PF07926.12 EAX72421.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX72421.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX72421.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX72422.1 - 1.8e-07 31.6 0.3 3.6e-07 30.7 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX72422.1 - 0.1 13.3 0.3 0.28 11.9 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4378 PF14309.6 EAX72423.1 - 0.02 15.2 0.1 0.13 12.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) AAA_22 PF13401.6 EAX72424.1 - 2.2e-05 24.8 0.2 0.00016 22.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72424.1 - 3.9e-05 23.5 0.3 0.3 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72424.1 - 9e-05 22.5 3.1 0.00019 21.5 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72424.1 - 0.0004 20.2 0.1 0.00074 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX72424.1 - 0.00051 19.6 2.4 0.00051 19.6 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72424.1 - 0.0014 18.3 0.5 0.01 15.5 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX72424.1 - 0.0016 18.2 1.2 0.0062 16.4 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72424.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72424.1 - 0.041 13.4 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72424.1 - 0.056 13.9 0.1 0.93 9.9 0.0 2.2 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX72424.1 - 0.058 12.9 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX72424.1 - 0.066 12.7 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72424.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX72424.1 - 0.24 11.7 4.9 4.6 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX72425.1 - 5.1e-05 22.8 1.4 8.2e-05 22.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1043 PF06295.12 EAX72426.1 - 0.06 13.3 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX72427.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX72427.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX72427.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX72427.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_D5 PF03288.16 EAX72428.1 - 2.5e-05 24.7 2.5 0.00014 22.2 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72428.1 - 0.028 15.1 0.1 0.05 14.2 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX72428.1 - 0.055 13.5 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX72429.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72430.1 - 0.76 9.7 2.7 1.7 8.6 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX72431.1 - 2.8e-24 85.9 7.0 1.4e-23 83.5 7.0 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72431.1 - 0.1 12.6 0.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAX72432.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX72433.1 - 0.051 14.0 1.4 0.065 13.7 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DDR PF08841.10 EAX72436.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX72436.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX72437.1 - 0.069 13.1 6.3 0.086 12.8 6.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX72437.1 - 2.2 5.8 10.7 2.4 5.7 10.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target PSP PF04046.16 EAX72438.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX72440.1 - 2.3e-73 245.7 4.4 2.8e-73 245.4 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX72440.1 - 0.18 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX72442.1 - 9.5e-10 38.4 5.6 2.1e-08 34.1 1.1 5.6 4 2 2 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX72442.1 - 0.096 12.4 1.3 0.29 10.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Spo12 PF05032.12 EAX72443.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX72444.1 - 5.6e-118 392.7 13.1 7.1e-118 392.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72444.1 - 0.092 12.6 1.8 0.26 11.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX72444.1 - 0.11 12.9 3.8 3.4 8.2 0.1 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX72444.1 - 0.25 10.8 1.0 0.96 8.9 0.1 2.4 2 1 0 2 2 2 0 SLOG cluster2 PRD PF00874.20 EAX72444.1 - 0.79 10.1 0.1 0.79 10.1 0.1 2.8 4 0 0 4 4 4 0 PRD domain DUF2408 PF10303.9 EAX72444.1 - 1.6 9.3 4.2 0.71 10.4 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX72445.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72445.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72445.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72445.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72445.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72445.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72445.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX72446.1 - 9.5e-112 372.3 11.0 1.2e-111 372.0 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72446.1 - 0.024 15.1 1.7 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX72447.1 - 1.1e-25 89.7 0.9 2e-25 88.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain PapD_N PF00345.20 EAX72449.1 - 0.032 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72449.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX72450.1 - 1.8e-59 201.2 3.6 2e-59 201.0 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX72451.1 - 6.5e-10 38.9 0.0 1.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX72452.1 - 1.3e-10 40.7 3.7 7.1e-10 38.3 3.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX72452.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX72452.1 - 0.11 12.4 0.0 0.75 9.8 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX72452.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF365 PF04033.12 EAX72453.1 - 0.05 13.9 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Ank_4 PF13637.6 EAX72454.1 - 2.9e-60 199.9 14.2 3.8e-14 52.8 0.2 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX72454.1 - 1.2e-49 166.8 26.8 6.5e-16 58.7 1.6 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX72454.1 - 1.4e-43 145.5 7.1 7.3e-07 29.4 0.1 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 EAX72454.1 - 1.6e-38 130.2 18.4 8.8e-13 48.2 0.3 4.5 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX72454.1 - 1.8e-38 126.1 5.4 5.6e-06 26.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat DUF3718 PF12514.8 EAX72454.1 - 0.00011 22.3 16.7 1.3 9.3 0.2 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3718) PAZ_siRNAbind PF12212.8 EAX72454.1 - 0.00025 20.9 0.5 9.4 6.1 0.0 4.6 1 1 4 5 5 5 1 PAZ domain CCDC84 PF14968.6 EAX72454.1 - 0.016 14.8 11.6 3.1 7.3 0.5 4.3 1 1 4 5 5 5 0 Coiled coil protein 84 C2 PF00168.30 EAX72454.1 - 0.017 15.4 0.0 6.8 7.0 0.0 3.3 3 1 1 4 4 4 0 C2 domain Prefoldin PF02996.17 EAX72454.1 - 0.032 14.1 0.1 16 5.4 0.0 3.2 1 1 1 3 3 3 0 Prefoldin subunit MTES_1575 PF18741.1 EAX72454.1 - 0.056 13.6 0.1 88 3.4 0.0 3.7 1 1 4 5 5 5 0 REase_MTES_1575 Stap_Strp_toxin PF01123.20 EAX72454.1 - 0.067 14.0 4.9 4.9 8.1 0.2 3.6 1 1 3 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF756 PF05506.12 EAX72454.1 - 0.087 13.8 1.0 29 5.6 0.5 4.1 1 1 1 2 2 2 0 Domain of unknown function (DUF756) PH_8 PF15409.6 EAX72454.1 - 0.098 13.0 1.9 49 4.3 0.1 3.7 1 1 2 4 4 4 0 Pleckstrin homology domain CinA_KH PF18146.1 EAX72454.1 - 0.13 12.5 1.1 68 3.7 0.0 3.6 3 1 1 4 4 4 0 Damage-inducible protein CinA KH domain S10_plectin PF03501.15 EAX72454.1 - 0.18 11.9 0.9 10 6.2 0.1 3.2 2 1 1 4 4 4 0 Plectin/S10 domain Env-gp36 PF09590.10 EAX72454.1 - 0.18 10.2 1.0 6.6 5.0 0.1 2.1 1 1 1 2 2 2 0 Lentivirus surface glycoprotein SAB PF04382.13 EAX72454.1 - 0.32 11.1 6.9 1.8e+02 2.3 0.0 5.5 6 0 0 6 6 6 0 SAB domain DUF3447 PF11929.8 EAX72455.1 - 4.5e-27 93.8 4.7 4.8e-27 93.7 4.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) DNA_pol_B_2 PF03175.13 EAX72456.1 - 1.6e-24 86.6 3.6 2.6e-24 85.9 3.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX72456.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX72456.1 - 0.034 14.2 0.9 0.87 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Amidase02_C PF12123.8 EAX72457.1 - 0.0052 16.4 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX72458.1 - 2.8e-07 30.3 1.1 1.1e-06 28.3 0.1 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72458.1 - 0.027 14.1 0.1 1.2 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72458.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72458.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTR PF12789.7 EAX72460.1 - 0.04 14.0 2.5 0.04 14.0 2.5 3.4 4 1 0 4 4 4 0 Phage tail repeat like DUF4795 PF16043.5 EAX72460.1 - 0.058 13.0 2.3 0.16 11.5 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX72461.1 - 7.4e-27 94.3 11.4 3.1e-26 92.3 11.4 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72461.1 - 0.085 12.8 0.0 0.92 9.5 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF1493 PF07377.12 EAX72462.1 - 0.026 15.0 0.8 0.052 14.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX72464.1 - 6.2e-07 29.2 0.3 1.3e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain IstB_IS21 PF01695.17 EAX72466.1 - 2.1e-05 24.3 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72466.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX72466.1 - 5.8e-05 22.7 1.9 5.8e-05 22.7 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX72466.1 - 0.00041 20.4 4.9 0.00059 19.9 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72466.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72466.1 - 0.0027 17.5 1.5 0.0058 16.5 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72466.1 - 0.0038 16.9 2.7 0.014 15.0 0.2 2.6 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72466.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX72466.1 - 0.064 13.3 0.7 1 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX72466.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72466.1 - 0.075 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72466.1 - 0.089 12.2 0.1 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72466.1 - 0.59 10.4 4.9 8.4 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX72466.1 - 3.2 8.5 10.6 0.28 11.9 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 GPS2_interact PF15784.5 EAX72467.1 - 0.12 12.9 1.7 0.15 12.5 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX72469.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Shikimate_DH PF01488.20 EAX72471.1 - 7.5 6.6 63.9 11 6.1 2.1 9.9 1 1 6 8 8 8 0 Shikimate / quinate 5-dehydrogenase Ribosomal_S6e PF01092.19 EAX72472.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S6e JMY PF15871.5 EAX72473.1 - 0.0097 15.3 0.6 0.014 14.7 0.6 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX72473.1 - 0.15 12.0 0.0 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX72473.1 - 0.37 10.8 2.5 0.52 10.4 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF1493 PF07377.12 EAX72475.1 - 0.013 15.9 0.4 0.025 15.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX72476.1 - 0.045 13.5 1.3 0.092 12.5 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Tfb5 PF06331.12 EAX72476.1 - 1.1 9.2 4.3 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 adh_short_C2 PF13561.6 EAX72476.1 - 1.6 8.2 4.2 4.1 6.9 4.3 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase PTR PF12789.7 EAX72477.1 - 0.024 14.7 1.9 0.024 14.7 1.9 3.2 4 1 0 4 4 4 0 Phage tail repeat like BRO1 PF03097.18 EAX72477.1 - 0.038 12.8 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX72477.1 - 0.083 12.5 2.5 0.21 11.1 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX72477.1 - 2.5 8.7 6.2 22 5.7 0.1 3.3 3 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX72477.1 - 6.6 7.2 15.3 3.4 8.1 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4107 PF13389.6 EAX72478.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72478.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX72478.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase MULE PF10551.9 EAX72479.1 - 4.1e-14 52.8 0.1 7.7e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain TMP PF05017.14 EAX72480.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX72481.1 - 0.028 14.9 0.9 0.063 13.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX72482.1 - 4.9e-06 26.2 0.4 5.6e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX72482.1 - 0.063 13.6 0.5 0.063 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) TEX29 PF15839.5 EAX72482.1 - 0.079 13.6 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein DUF4841 PF16129.5 EAX72482.1 - 0.12 12.6 0.2 0.28 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) DUF4108 PF13390.6 EAX72483.1 - 5.2e-57 191.8 3.5 5.8e-57 191.6 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72484.1 - 0.15 12.0 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Adaptin_binding PF10199.9 EAX72486.1 - 4 8.1 13.7 5.8 7.5 13.7 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TP53IP5 PF15331.6 EAX72486.1 - 4.1 7.5 15.0 4.8 7.3 15.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NPIP PF06409.11 EAX72486.1 - 4.6 6.2 18.5 0.2 10.7 0.9 2.0 1 1 1 2 2 2 0 Nuclear pore complex interacting protein (NPIP) FAS_N PF17828.1 EAX72488.1 - 0.011 15.7 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72489.1 - 0.016 15.6 0.4 0.022 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF1146 PF06612.11 EAX72490.1 - 0.014 15.4 0.1 0.053 13.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX72490.1 - 0.087 12.9 0.5 0.36 11.0 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) zf-BED PF02892.15 EAX72490.1 - 8.6 6.5 9.0 11 6.2 0.3 2.8 2 1 0 2 2 2 0 BED zinc finger VirE PF05272.11 EAX72491.1 - 8.7e-06 25.6 0.1 1.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX72491.1 - 0.058 13.8 0.1 0.13 12.7 0.1 1.7 1 1 0 1 1 1 0 RNA helicase PTR PF12789.7 EAX72492.1 - 3.6e-15 55.7 1.4 3.6e-15 55.7 1.4 5.4 3 2 2 5 5 5 1 Phage tail repeat like DUF3391 PF11871.8 EAX72492.1 - 0.0098 16.4 3.3 1.2 9.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX72492.1 - 0.038 13.7 0.9 0.079 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX72492.1 - 5.9 6.4 19.2 0.045 13.3 5.2 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) T5orf172 PF10544.9 EAX72493.1 - 1.4e-07 32.0 0.8 1.9e-06 28.3 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX72493.1 - 0.016 14.7 0.8 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain RNF111_N PF15303.6 EAX72494.1 - 6.6 6.4 11.5 10 5.8 11.5 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3839 PF12943.7 EAX72495.1 - 5.3e-94 314.2 8.6 6.1e-94 314.0 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX72496.1 - 6.8e-80 268.0 11.1 8.8e-80 267.6 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72496.1 - 0.092 12.3 0.5 0.34 10.4 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 KilA-N PF04383.13 EAX72497.1 - 4.2e-41 139.3 1.1 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX72497.1 - 0.45 10.5 2.9 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein ResIII PF04851.15 EAX72498.1 - 2.2e-05 24.5 1.1 3.8e-05 23.7 1.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72498.1 - 0.00029 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX72498.1 - 0.00041 20.6 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX72498.1 - 0.0015 18.4 0.2 0.0022 17.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72498.1 - 0.0067 16.8 0.0 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX72498.1 - 0.034 13.6 0.1 0.044 13.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX72498.1 - 0.059 13.0 0.3 0.097 12.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX72498.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX72498.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX72498.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX72498.1 - 0.46 10.9 2.7 0.43 11.0 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX72499.1 - 2.6e-158 524.8 13.8 3.1e-158 524.5 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72499.1 - 0.18 12.3 4.9 2.5 8.6 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX72499.1 - 1.9 9.0 5.5 0.87 10.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_D5 PF03288.16 EAX72500.1 - 0.00031 21.2 2.8 0.0019 18.7 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72500.1 - 0.049 14.3 0.2 0.11 13.2 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX72500.1 - 0.051 12.7 1.0 0.067 12.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX72501.1 - 3e-40 138.2 5.0 4.2e-40 137.7 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72501.1 - 0.11 12.0 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX72502.1 - 5.8e-08 32.5 1.3 7.3e-08 32.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72502.1 - 0.0041 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72502.1 - 0.046 13.4 0.1 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72502.1 - 0.071 13.1 0.4 0.63 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX72503.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72503.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72503.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72503.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72503.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72503.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72503.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72503.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72503.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72503.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72503.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72503.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX72504.1 - 1e-24 86.3 18.1 7.3e-17 61.2 1.9 4.3 3 1 0 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX72504.1 - 0.032 14.0 0.1 0.097 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX72504.1 - 0.28 11.1 7.2 1.3 9.0 1.2 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF240) CppA_C PF14507.6 EAX72504.1 - 2 9.2 5.8 0.96 10.2 0.3 2.7 2 1 0 2 2 2 0 CppA C-terminal DUF1493 PF07377.12 EAX72505.1 - 0.032 14.7 0.8 0.055 13.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX72506.1 - 2.2e-06 27.3 2.2 2.2e-06 27.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72506.1 - 3e-05 23.8 0.5 0.37 10.5 0.2 2.9 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72506.1 - 3.8e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72506.1 - 0.00015 21.8 3.0 0.00036 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72506.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72506.1 - 0.0018 18.1 0.5 0.005 16.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72506.1 - 0.0022 17.6 0.4 0.013 15.1 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72506.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72506.1 - 0.067 12.8 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX72506.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX72506.1 - 0.097 13.1 0.1 0.76 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX72506.1 - 0.15 12.4 2.4 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX72506.1 - 0.71 10.2 4.5 11 6.4 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX72507.1 - 8.6e-06 25.4 0.9 1e-05 25.2 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX72507.1 - 0.0037 17.3 0.1 0.0071 16.4 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX72507.1 - 0.064 13.5 0.5 0.064 13.5 0.5 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) KilA-N PF04383.13 EAX72508.1 - 3.6e-43 146.0 0.7 7.6e-43 144.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72508.1 - 0.025 15.2 0.1 0.063 13.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Spo12 PF05032.12 EAX72509.1 - 2.4 8.2 8.9 0.91 9.5 3.5 2.6 3 0 0 3 3 3 0 Spo12 family PTR PF12789.7 EAX72510.1 - 1.3e-49 166.1 33.1 3.3e-33 113.5 17.1 4.7 2 2 3 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX72510.1 - 0.026 14.2 0.1 0.077 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX72510.1 - 0.28 11.5 3.7 8 6.9 0.2 3.4 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF1524 PF07510.11 EAX72510.1 - 1.8 8.4 14.5 0.17 11.7 2.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1524) DUF4107 PF13389.6 EAX72511.1 - 7e-71 237.6 3.2 9.2e-71 237.2 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72511.1 - 0.096 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX72512.1 - 5.3e-34 116.4 0.2 7.2e-34 116.0 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX72512.1 - 0.12 12.4 0.4 0.13 12.2 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAX72513.1 - 2.4e-29 102.5 6.9 3.3e-29 102.0 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX72514.1 - 2.6e-10 40.2 9.7 8.1e-09 35.4 5.6 4.7 4 1 0 4 4 4 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX72514.1 - 0.039 14.2 0.0 9.7 6.4 0.0 2.3 1 1 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain EpuA PF11772.8 EAX72514.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta HD_2 PF12917.7 EAX72514.1 - 0.14 11.9 1.2 11 5.7 0.1 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme IL2 PF00715.17 EAX72514.1 - 0.18 11.7 2.1 5.4 6.9 0.1 2.5 3 0 0 3 3 3 0 Interleukin 2 VirE PF05272.11 EAX72517.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.9 EAX72517.1 - 0.064 12.2 0.1 6.8 5.5 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EAX72517.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PTR PF12789.7 EAX72519.1 - 2.8e-23 81.7 20.2 2.2e-16 59.6 2.0 5.1 4 1 1 5 5 5 2 Phage tail repeat like DUF3391 PF11871.8 EAX72519.1 - 0.066 13.8 0.4 0.58 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Plk4_PB1 PF18190.1 EAX72519.1 - 0.11 12.6 5.9 0.67 10.1 0.1 2.8 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 1 DUF4795 PF16043.5 EAX72519.1 - 2.3 7.8 20.0 0.057 13.0 5.8 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) MULE PF10551.9 EAX72520.1 - 6.8e-11 42.5 0.2 1.2e-10 41.6 0.2 1.4 1 0 0 1 1 1 1 MULE transposase domain FAS_N PF17828.1 EAX72521.1 - 0.022 14.8 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72522.1 - 0.0042 17.5 0.7 0.005 17.2 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72522.1 - 3.4 7.6 6.9 3.7 7.5 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX72523.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72523.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72523.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72523.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DNA_pol_B_2 PF03175.13 EAX72524.1 - 1.1e-17 64.0 6.1 5.4e-17 61.8 5.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72524.1 - 0.15 12.0 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX72524.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX72525.1 - 4e-158 524.2 14.0 4.6e-158 523.9 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72525.1 - 0.13 12.1 1.5 0.41 10.5 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX72525.1 - 0.73 10.3 7.7 2 9.0 0.9 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX72525.1 - 0.82 10.0 3.2 2.2 8.6 0.0 2.9 2 2 1 3 3 3 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX72526.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72526.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72526.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72526.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX72527.1 - 8.3e-08 32.7 0.4 1.7e-07 31.7 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX72527.1 - 0.088 13.5 0.5 0.24 12.1 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3839 PF12943.7 EAX72528.1 - 3.5e-155 514.5 13.7 4.1e-155 514.3 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72528.1 - 4.8 7.7 6.7 2.5 8.6 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX72529.1 - 2.3e-05 24.3 0.6 2.3e-05 24.3 0.6 4.0 2 1 2 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX72529.1 - 0.015 15.0 0.1 0.07 12.9 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX72529.1 - 0.12 12.2 10.1 0.11 12.2 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX72529.1 - 0.13 12.8 5.3 0.18 12.3 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX72529.1 - 0.14 11.1 1.7 0.21 10.5 1.7 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Transposase_24 PF03004.14 EAX72529.1 - 5.2 7.2 8.3 0.81 9.8 0.9 2.9 2 2 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) Mito_fiss_reg PF05308.11 EAX72530.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72530.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4106 PF13388.6 EAX72531.1 - 1.7e-200 666.6 25.0 2.2e-200 666.3 25.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX72531.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX72531.1 - 1.8 8.4 30.5 0.32 10.9 19.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DNA_pol_B_2 PF03175.13 EAX72532.1 - 1.1e-19 70.6 12.0 4.6e-19 68.6 12.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX72532.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX72535.1 - 5.4e-50 170.1 4.7 7e-50 169.7 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX72535.1 - 0.045 14.2 0.5 0.95 10.0 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DNA_pol_B_2 PF03175.13 EAX72536.1 - 5.3e-25 88.2 11.1 2.3e-24 86.1 11.1 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72536.1 - 0.11 12.5 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Amidase02_C PF12123.8 EAX72538.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX72539.1 - 2.6e-41 140.0 0.4 6.6e-41 138.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX72539.1 - 0.2 11.7 2.9 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX72540.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72540.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72540.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72540.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72540.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72540.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72540.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72540.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72540.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72540.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72540.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72540.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX72543.1 - 4.4e-29 101.7 7.3 7.9e-29 100.8 7.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX72543.1 - 0.051 12.9 0.1 0.076 12.3 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX72543.1 - 0.097 12.7 1.1 2 8.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) La PF05383.17 EAX72544.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 La domain Ank_2 PF12796.7 EAX72545.1 - 2.5e-34 117.7 1.9 6.4e-15 55.5 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX72545.1 - 8.6e-34 115.5 3.7 4.8e-10 39.8 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX72545.1 - 1.8e-30 104.6 0.4 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX72545.1 - 2.2e-26 89.0 1.8 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX72545.1 - 4.7e-24 83.7 3.2 0.00026 21.3 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 EAX72545.1 - 0.0036 17.2 0.9 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) PTR PF12789.7 EAX72547.1 - 1.1e-11 44.6 17.7 2.7e-08 33.8 4.6 4.9 4 1 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX72547.1 - 0.079 12.5 15.5 1.3 8.6 2.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX72548.1 - 0.026 15.0 0.4 0.05 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX72548.1 - 0.42 10.7 3.9 7.8 6.6 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX72549.1 - 1.4e-08 34.6 0.8 1.4e-08 34.6 0.8 3.0 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX72549.1 - 0.012 15.4 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF167 PF02594.16 EAX72549.1 - 0.15 12.2 0.5 3.9 7.7 0.2 2.7 1 1 1 2 2 2 0 Uncharacterised ACR, YggU family COG1872 YmaF PF12788.7 EAX72550.1 - 0.87 10.2 4.3 18 5.9 0.1 3.1 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX72550.1 - 1.9 8.9 14.9 3.6 8.0 0.3 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4795 PF16043.5 EAX72550.1 - 2.4 7.7 5.2 18 4.8 5.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX72551.1 - 1.1e-24 87.2 7.5 8.4e-24 84.3 7.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72551.1 - 0.069 13.1 0.0 0.82 9.7 0.0 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX72551.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PSP PF04046.16 EAX72552.1 - 0.067 13.1 0.8 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP Gly-zipper_Omp PF13488.6 EAX72554.1 - 0.0087 16.0 7.7 0.015 15.3 7.7 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX72554.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX72554.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX72554.1 - 0.33 11.3 4.2 0.51 10.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) ArsC PF03960.15 EAX72555.1 - 0.16 12.0 1.0 0.28 11.2 1.0 1.5 1 1 0 1 1 1 0 ArsC family PTR PF12789.7 EAX72556.1 - 6.5e-11 42.1 22.1 2.7e-08 33.7 4.6 4.9 5 1 1 6 6 6 2 Phage tail repeat like DUF480 PF04337.12 EAX72556.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 DUF4795 PF16043.5 EAX72556.1 - 0.07 12.7 14.6 1.5 8.4 2.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX72556.1 - 0.39 11.3 10.2 8.8 6.9 1.5 4.2 3 2 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX72556.1 - 3.8 7.9 23.2 4.1 7.8 0.3 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX72557.1 - 4.4e-79 265.4 10.0 5.6e-79 265.0 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX72561.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72561.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72561.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72561.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF5623 PF18536.1 EAX72563.1 - 0.014 15.6 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX72563.1 - 0.43 10.5 8.0 0.15 12.0 2.9 2.2 2 0 0 2 2 2 0 Spo12 family DUF4108 PF13390.6 EAX72564.1 - 2.1e-61 206.0 7.8 2.3e-61 205.9 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3213 PF11491.8 EAX72566.1 - 0.037 14.2 0.5 0.086 13.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX72568.1 - 1.4e-05 25.6 0.1 3.3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72568.1 - 0.014 15.2 0.9 0.095 12.6 0.3 2.4 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX72568.1 - 0.055 13.0 0.3 0.34 10.4 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain Phage_TAC_2 PF06894.11 EAX72569.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G DUF3839 PF12943.7 EAX72572.1 - 1.2e-91 306.5 8.9 1.4e-91 306.3 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX72572.1 - 0.15 12.4 1.3 0.3 11.4 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF5398 PF17376.2 EAX72572.1 - 2.1 9.0 4.9 2.1 9.0 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) PTR PF12789.7 EAX72573.1 - 4e-10 39.6 21.2 1.7e-08 34.4 0.3 4.9 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX72573.1 - 0.31 10.6 9.3 0.44 10.1 3.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX72573.1 - 1.3 9.6 10.1 20 5.8 0.1 3.8 3 2 0 3 3 3 0 YmaF family DUF3839 PF12943.7 EAX72574.1 - 3.3e-39 134.8 5.0 4.6e-39 134.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX72574.1 - 0.43 11.0 2.3 1.4 9.3 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF2939 PF11159.8 EAX72575.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72575.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX72576.1 - 0.017 15.1 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2400 PF09674.10 EAX72576.1 - 0.025 14.6 0.5 0.033 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) ARA70 PF12489.8 EAX72579.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator TMP PF05017.14 EAX72580.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX72581.1 - 2.7e-217 722.0 28.3 6.3e-217 720.7 28.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX72581.1 - 0.016 15.0 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) KAR PF15222.6 EAX72581.1 - 0.12 12.7 0.0 2.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated TFIIA PF03153.13 EAX72581.1 - 0.15 12.0 22.4 0.2 11.6 22.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4106 PF13388.6 EAX72582.1 - 1e-07 31.6 6.8 1e-07 31.6 6.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Bd3614-deam PF14439.6 EAX72583.1 - 0.082 13.0 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Pox_A32 PF04665.12 EAX72584.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72584.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72584.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72584.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX72585.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72585.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72585.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72585.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX72586.1 - 6.6e-79 264.8 10.4 8.9e-79 264.3 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72586.1 - 0.13 12.1 1.1 0.43 10.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_D5 PF03288.16 EAX72587.1 - 4.4e-05 23.9 1.9 0.0002 21.8 1.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX72587.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) KilA-N PF04383.13 EAX72588.1 - 1e-19 70.5 1.4 1.8e-19 69.6 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX72589.1 - 2.3e-07 30.5 0.6 1.7e-06 27.7 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX72589.1 - 0.06 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX72589.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX72589.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX72590.1 - 4e-80 268.8 10.4 5.1e-80 268.4 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72590.1 - 0.076 12.5 0.8 0.47 9.9 0.0 2.3 2 1 0 3 3 3 0 SLOG cluster2 DUF4107 PF13389.6 EAX72591.1 - 2.6e-73 245.5 3.9 3.3e-73 245.2 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX72593.1 - 1.1e-06 28.3 2.3 1.1e-06 28.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72593.1 - 2.5e-05 24.5 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72593.1 - 4.5e-05 23.3 0.2 0.32 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72593.1 - 0.00014 21.9 3.1 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72593.1 - 0.00054 19.8 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72593.1 - 0.0012 18.7 0.6 0.003 17.4 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72593.1 - 0.0017 18.0 0.4 0.012 15.3 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72593.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX72593.1 - 0.064 12.7 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX72593.1 - 0.064 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72593.1 - 0.081 13.4 0.1 0.67 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72593.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72593.1 - 0.3 11.3 3.8 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX72594.1 - 1.7e-181 604.0 23.7 6.4e-181 602.1 23.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX72594.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PTR PF12789.7 EAX72595.1 - 8.3e-28 96.2 12.2 8.3e-28 96.2 12.2 3.1 4 0 0 4 4 4 1 Phage tail repeat like AAA_22 PF13401.6 EAX72599.1 - 1.8e-05 25.1 0.2 0.00013 22.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72599.1 - 8.7e-05 22.6 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX72599.1 - 8.9e-05 22.3 0.3 0.52 10.0 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX72599.1 - 0.0004 20.2 0.1 0.00063 19.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72599.1 - 0.001 18.9 0.7 0.0027 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX72599.1 - 0.0016 17.9 3.1 0.0017 17.9 1.4 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX72599.1 - 0.0089 16.4 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX72599.1 - 0.037 13.6 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX72599.1 - 0.052 13.0 0.1 0.083 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Elong_Iki1 PF10483.9 EAX72599.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX72599.1 - 0.058 13.8 0.1 0.43 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX72599.1 - 0.086 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF4795 PF16043.5 EAX72600.1 - 0.0036 16.9 4.2 0.027 14.1 4.2 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX72600.1 - 0.3 11.3 5.0 2.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF2897 PF11446.8 EAX72601.1 - 0.41 10.6 3.7 0.81 9.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX72602.1 - 6.1e-05 23.1 3.1 0.00012 22.2 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX72602.1 - 9.6e-05 22.7 0.1 0.00041 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX72602.1 - 0.00037 20.3 0.0 0.0005 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72602.1 - 0.0012 18.7 1.5 0.0041 16.9 1.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72602.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72602.1 - 0.017 14.9 0.2 0.3 10.8 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX72602.1 - 0.04 13.4 0.1 0.064 12.7 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72602.1 - 0.067 13.0 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX72602.1 - 0.12 12.8 0.0 0.35 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX72602.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX72602.1 - 0.59 10.4 3.6 28 5.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX72603.1 - 1.6e-238 791.9 39.8 1.4e-124 416.6 21.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX72603.1 - 0.021 14.6 0.2 0.052 13.4 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) KilA-N PF04383.13 EAX72604.1 - 2.7e-41 139.9 0.6 7.3e-41 138.5 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain GDE_C PF06202.14 EAX72605.1 - 0.00097 18.2 1.2 0.28 10.1 0.1 2.1 1 1 1 2 2 2 2 Amylo-alpha-1,6-glucosidase DUF2379 PF09543.10 EAX72605.1 - 0.0019 18.4 1.9 1 9.6 0.1 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF2379) VWA_2 PF13519.6 EAX72605.1 - 0.24 12.1 3.5 38 5.0 0.2 3.5 1 1 3 4 4 4 0 von Willebrand factor type A domain PTR PF12789.7 EAX72606.1 - 1.2e-13 50.9 3.3 1.2e-13 50.9 3.3 3.0 4 0 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX72606.1 - 0.016 15.7 5.7 4.7 7.8 0.2 3.3 2 1 0 2 2 2 0 YmaF family TMP PF05017.14 EAX72607.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX72608.1 - 0.029 14.9 0.6 0.076 13.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Gly-zipper_Omp PF13488.6 EAX72609.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX72609.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX72609.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF257 PF03192.13 EAX72610.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX72610.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4107 PF13389.6 EAX72611.1 - 6.9e-53 179.1 0.9 9.1e-53 178.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX72613.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX72614.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX72615.1 - 0.017 15.5 0.4 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72615.1 - 1.6 8.8 5.4 1.7 8.7 5.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 L27_1 PF09058.10 EAX72616.1 - 0.0013 18.6 0.7 0.079 13.0 0.0 2.5 2 0 0 2 2 2 2 L27_1 Amidase02_C PF12123.8 EAX72617.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DDR PF08841.10 EAX72620.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX72620.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX72621.1 - 0.027 14.4 10.5 0.03 14.3 10.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72621.1 - 7 7.1 7.8 8.7 6.8 7.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Cation_efflux PF01545.21 EAX72622.1 - 6.1e-20 71.8 1.0 7.7e-20 71.5 1.0 1.1 1 0 0 1 1 1 1 Cation efflux family GPS2_interact PF15784.5 EAX72623.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72623.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72624.1 - 0.088 12.8 7.6 0.13 12.2 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72624.1 - 4.3 7.8 6.0 6.4 7.2 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX72625.1 - 6.1e-22 78.1 11.0 2.3e-21 76.2 11.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX72627.1 - 2e-07 30.2 1.6 8.5e-07 28.2 1.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72627.1 - 0.034 14.1 0.0 0.4 10.7 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PSP PF04046.16 EAX72628.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72629.1 - 0.039 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX72630.1 - 2.4e-06 28.0 0.2 5.9e-06 26.8 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72630.1 - 0.0064 16.3 2.3 0.023 14.5 0.6 2.5 2 2 0 2 2 2 1 KilA-N domain RLL PF10036.9 EAX72631.1 - 0.011 15.5 3.7 0.014 15.3 3.7 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein RNA_polI_A34 PF08208.11 EAX72631.1 - 0.12 12.4 14.0 0.12 12.5 14.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2897 PF11446.8 EAX72631.1 - 3.8 7.5 6.6 6.7 6.7 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX72632.1 - 2.5e-61 205.8 7.1 2.7e-61 205.7 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RFX_DNA_binding PF02257.15 EAX72633.1 - 0.00014 22.4 0.1 0.0002 21.9 0.1 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX72633.1 - 0.0011 19.4 1.7 0.0018 18.8 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX72633.1 - 0.051 13.6 0.9 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX72634.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX72634.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX72634.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PSP PF04046.16 EAX72636.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX72637.1 - 1e-80 270.7 10.5 1.3e-80 270.3 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX72637.1 - 0.11 13.0 0.3 0.2 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) GPS2_interact PF15784.5 EAX72638.1 - 0.014 15.9 0.6 0.017 15.6 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72638.1 - 0.077 12.0 0.1 0.08 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX72639.1 - 7.9e-32 109.4 0.0 1.5e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain DUF5568 PF17724.1 EAX72639.1 - 0.16 11.7 0.1 1.2 8.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5568) T5orf172 PF10544.9 EAX72640.1 - 1e-06 29.2 0.1 2.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72640.1 - 0.0072 16.2 0.2 0.065 13.1 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain DUF257 PF03192.13 EAX72641.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX72641.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PadR PF03551.14 EAX72642.1 - 0.055 13.4 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX72644.1 - 2.9e-32 110.5 9.4 2.9e-32 110.5 9.4 3.6 2 1 1 3 3 3 1 Phage tail repeat like DUF2357 PF09823.9 EAX72644.1 - 0.021 14.1 1.3 0.03 13.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF240 PF03086.14 EAX72644.1 - 1.3 9.0 8.8 1.3 9.0 1.5 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX72645.1 - 0.014 15.9 1.4 0.018 15.5 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX72646.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX72648.1 - 5.2e-08 32.7 0.7 5.9e-08 32.5 0.7 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72648.1 - 0.0055 16.4 0.1 0.0058 16.3 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX72648.1 - 0.06 13.3 0.4 0.56 10.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX72648.1 - 0.073 12.8 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX72650.1 - 4.5e-153 507.6 9.8 5.1e-153 507.4 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72650.1 - 0.035 14.6 7.0 0.38 11.2 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX72650.1 - 0.69 10.3 4.9 8.4 6.8 0.1 3.4 3 2 1 4 4 4 0 Tup N-terminal LRR_5 PF13306.6 EAX72651.1 - 6.2e-19 68.2 9.6 2.1e-18 66.5 9.6 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX72651.1 - 0.00097 18.9 0.6 1.6 8.6 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat DUF1493 PF07377.12 EAX72652.1 - 0.038 14.5 0.9 0.076 13.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX72653.1 - 3.2e-10 39.5 2.6 2e-09 36.8 2.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72653.1 - 0.12 12.4 0.0 0.92 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF2666 PF10869.8 EAX72654.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2666) DUF1043 PF06295.12 EAX72655.1 - 0.031 14.3 0.4 0.053 13.5 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX72656.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX72656.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX72657.1 - 0.011 15.8 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX72658.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72658.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72658.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72658.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72658.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72658.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72658.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX72659.1 - 1.3e-39 134.5 0.5 3e-39 133.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72659.1 - 0.0055 17.3 0.2 0.018 15.7 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family Gly-zipper_Omp PF13488.6 EAX72660.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX72660.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX72660.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ARA70 PF12489.8 EAX72661.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator KilA-N PF04383.13 EAX72662.1 - 4.4e-42 142.5 0.1 7.1e-42 141.8 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain TMP PF05017.14 EAX72664.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat N_Asn_amidohyd PF14736.6 EAX72666.1 - 0.052 12.7 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Amidase02_C PF12123.8 EAX72667.1 - 0.019 14.7 0.1 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX72668.1 - 3.2e-23 82.4 4.4 4e-23 82.0 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAX72669.1 - 6.9e-07 29.8 0.1 1.5e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72669.1 - 0.032 14.1 0.5 0.33 10.8 0.0 2.3 2 1 0 2 2 2 0 KilA-N domain T5orf172 PF10544.9 EAX72670.1 - 2.5e-06 27.9 0.4 8.3e-06 26.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX72670.1 - 0.0097 15.5 0.7 0.15 11.6 0.1 2.2 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX72670.1 - 0.038 13.8 0.6 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 KilA-N domain DUF4107 PF13389.6 EAX72671.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX72672.1 - 7.2e-79 264.7 10.4 9.3e-79 264.3 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX72672.1 - 0.071 13.3 0.2 0.17 12.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 T5orf172 PF10544.9 EAX72673.1 - 9.5e-07 29.3 0.3 2.5e-06 28.0 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX72673.1 - 0.13 11.8 0.5 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX72675.1 - 4.4e-80 268.6 11.6 5.8e-80 268.2 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72675.1 - 0.038 14.5 0.3 0.044 14.2 0.3 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX72675.1 - 0.066 12.7 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX72675.1 - 0.12 13.0 0.7 0.19 12.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX72676.1 - 3.6e-09 36.0 0.1 7.8e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX72676.1 - 0.01 15.2 0.4 0.014 14.7 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX72676.1 - 0.22 11.6 1.1 0.5 10.4 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5065) KilA-N PF04383.13 EAX72679.1 - 3.8e-44 149.1 0.1 7.7e-44 148.1 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX72679.1 - 0.003 18.2 0.1 0.0086 16.7 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family Mito_fiss_reg PF05308.11 EAX72680.1 - 0.026 14.6 1.8 0.028 14.5 1.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72680.1 - 0.27 10.7 5.5 0.26 10.7 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF5365 PF17326.2 EAX72681.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PSP PF04046.16 EAX72682.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72683.1 - 0.068 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat GGDEF PF00990.21 EAX72685.1 - 0.0094 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX72685.1 - 0.15 12.4 9.7 0.2 11.9 9.7 1.4 1 1 0 1 1 1 0 PcfK-like protein ResIII PF04851.15 EAX72686.1 - 6.2e-05 23.1 2.8 0.00012 22.1 2.8 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72686.1 - 0.00036 20.3 0.0 0.0005 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX72686.1 - 0.00039 20.7 0.0 0.00065 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX72686.1 - 0.00073 19.4 1.0 0.0022 17.9 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72686.1 - 0.0071 16.7 0.0 0.0096 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72686.1 - 0.039 13.7 0.3 0.28 10.9 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX72686.1 - 0.043 13.3 0.1 0.059 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX72686.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX72686.1 - 0.15 12.3 4.5 3.5 7.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX72686.1 - 0.25 11.0 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX72687.1 - 8.9e-26 90.8 0.3 9.6e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX72689.1 - 4.6e-138 458.5 11.7 5.1e-138 458.3 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX72689.1 - 0.029 14.6 0.1 0.091 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAX72689.1 - 0.19 12.4 1.9 0.53 10.9 0.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX72689.1 - 0.45 11.0 2.6 1 9.9 0.7 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX72690.1 - 2.3e-57 192.9 4.2 2.5e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX72691.1 - 4.2e-17 62.2 5.6 5.6e-17 61.8 5.6 1.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX72691.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Antimicrobial_7 PF08102.11 EAX72693.1 - 0.046 13.9 0.8 0.091 13.0 0.3 1.8 1 1 1 2 2 2 0 Scorpion antimicrobial peptide ARA70 PF12489.8 EAX72693.1 - 0.083 13.1 0.1 0.095 12.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear coactivator GREB1 PF15782.5 EAX72694.1 - 0.73 6.9 19.1 1.1 6.3 19.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer T3SS_needle_E PF08988.10 EAX72694.1 - 2.7 8.2 9.4 14 5.9 1.0 2.6 1 1 1 2 2 2 0 Type III secretion system, cytoplasmic E component of needle PTR PF12789.7 EAX72695.1 - 1.7e-47 159.3 44.7 2.2e-29 101.3 18.4 2.8 1 1 1 2 2 2 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX72695.1 - 0.18 12.1 5.2 6.7 7.1 0.3 3.1 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain TMP PF05017.14 EAX72697.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72698.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP AAA_22 PF13401.6 EAX72700.1 - 2e-05 24.9 0.2 0.00015 22.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72700.1 - 2.6e-05 24.1 0.3 0.31 10.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX72700.1 - 4.1e-05 23.2 1.9 4.1e-05 23.2 1.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX72700.1 - 0.00011 22.2 3.1 0.00023 21.2 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72700.1 - 0.00039 20.2 0.1 0.00069 19.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX72700.1 - 0.0014 18.3 0.5 0.01 15.5 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX72700.1 - 0.0015 18.4 1.0 0.0042 16.9 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72700.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX72700.1 - 0.048 13.2 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX72700.1 - 0.052 13.0 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX72700.1 - 0.06 13.8 0.1 0.53 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72700.1 - 0.071 12.6 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72700.1 - 0.09 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72700.1 - 0.26 11.3 2.2 1.5 8.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX72700.1 - 0.33 11.2 4.5 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GPS2_interact PF15784.5 EAX72701.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX72702.1 - 0.057 13.4 6.0 0.09 12.8 6.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) T5orf172 PF10544.9 EAX72704.1 - 9.7e-07 29.3 0.3 1.9e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72705.1 - 1.4e-22 79.7 0.0 2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX72705.1 - 0.045 13.7 0.5 0.05 13.6 0.5 1.0 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF846 PF05832.12 EAX72707.1 - 0.053 13.5 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF3035 PF11233.8 EAX72708.1 - 0.012 15.9 2.2 0.023 15.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) RNase_J_C PF17770.1 EAX72708.1 - 0.29 12.2 2.9 95 4.2 0.0 3.4 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain Herpes_UL25 PF01499.16 EAX72709.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2939 PF11159.8 EAX72710.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX72711.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX72712.1 - 2.7e-71 239.0 3.9 3.7e-71 238.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX72712.1 - 0.15 10.5 0.4 0.2 10.0 0.4 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4107 PF13389.6 EAX72715.1 - 8.8e-73 243.8 4.2 1.1e-72 243.4 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72715.1 - 0.065 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX72717.1 - 2.1e-53 180.1 7.8 2.3e-53 180.0 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72718.1 - 1.7 8.6 3.7 3.7 7.5 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX72719.1 - 8e-50 169.2 1.6 9.3e-50 168.9 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1731 PF08338.11 EAX72721.1 - 0.15 12.0 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX72723.1 - 7.8e-43 144.9 0.7 1.6e-42 143.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72723.1 - 0.025 15.2 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF4106 PF13388.6 EAX72724.1 - 1.1e-95 321.4 5.3 1.2e-95 321.2 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) PapD_N PF00345.20 EAX72725.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72725.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Trypan_PARP PF05887.11 EAX72728.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72728.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX72730.1 - 2.2e-16 59.7 0.3 6.2e-16 58.2 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72730.1 - 0.019 15.6 0.0 0.04 14.5 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family PTR PF12789.7 EAX72732.1 - 2.5e-25 88.3 10.0 2.5e-25 88.3 10.0 3.8 3 1 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX72732.1 - 2.7 8.6 17.1 9.6 6.8 7.5 3.7 2 2 0 2 2 2 0 YmaF family Ank_4 PF13637.6 EAX72736.1 - 5.7e-121 393.5 38.6 1.9e-14 53.8 0.2 11.0 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX72736.1 - 1.7e-97 316.0 34.2 6.9e-09 35.8 0.1 12.0 12 0 0 12 12 12 12 Ankyrin repeat Ank_2 PF12796.7 EAX72736.1 - 7.3e-97 318.1 68.8 1.8e-20 73.3 4.5 6.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX72736.1 - 2.1e-75 239.6 26.3 1.1e-06 28.5 0.1 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX72736.1 - 2.3e-61 203.1 38.1 1e-09 38.5 0.0 7.4 2 2 6 9 9 9 9 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX72736.1 - 3.5e-15 56.0 1.8 0.018 15.3 0.0 7.1 1 1 4 6 6 6 3 N terminal of Calcineurin-like phosphoesterase SAB PF04382.13 EAX72736.1 - 0.00048 20.1 38.6 45 4.2 0.1 11.7 12 0 0 12 12 12 0 SAB domain RNase_PH_C PF03725.15 EAX72736.1 - 0.00062 19.7 16.1 13 5.9 0.0 8.0 6 4 4 10 10 10 0 3' exoribonuclease family, domain 2 DUF3130 PF11328.8 EAX72736.1 - 0.0058 16.8 20.0 4.3 7.7 0.2 6.8 1 1 1 6 6 6 1 Protein of unknown function (DUF3130 DUF2028 PF09667.10 EAX72736.1 - 0.42 10.6 4.5 71 3.3 0.1 4.6 2 2 1 5 5 5 0 Domain of unknown function (DUF2028) ApbA_C PF08546.11 EAX72736.1 - 1.7 8.9 15.2 92 3.3 0.4 6.6 1 1 3 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal Ribosomal_S6 PF01250.17 EAX72736.1 - 2 8.7 14.5 38 4.6 0.1 5.8 2 2 4 7 7 7 0 Ribosomal protein S6 Clathrin PF00637.20 EAX72736.1 - 2.9 7.8 22.3 41 4.0 0.3 6.7 1 1 6 7 7 7 0 Region in Clathrin and VPS Lipoprotein_3 PF00938.17 EAX72736.1 - 4.8 7.5 23.7 53 4.1 0.2 7.4 1 1 6 9 9 9 0 Lipoprotein Pox_A32 PF04665.12 EAX72737.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72737.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72737.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72737.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72737.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72737.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72737.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX72738.1 - 2.7e-07 30.3 1.2 4.4e-07 29.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX72739.1 - 8e-143 474.1 8.6 9.1e-143 473.9 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX72739.1 - 0.13 12.8 2.0 4.5 7.8 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX72739.1 - 0.14 12.7 4.9 1.3 9.5 0.6 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf_CopZ PF18423.1 EAX72739.1 - 0.19 11.7 0.3 0.19 11.7 0.3 1.9 2 0 0 2 2 2 0 Zinc binding domain GPS2_interact PF15784.5 EAX72741.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72741.1 - 0.11 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX72742.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72742.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72742.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72742.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72742.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72742.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72742.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Tmemb_9 PF05434.11 EAX72745.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 T5orf172 PF10544.9 EAX72748.1 - 3.4e-07 30.7 0.3 6.9e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72749.1 - 4.2e-42 142.5 0.6 7.4e-42 141.7 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72749.1 - 0.012 16.3 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX72750.1 - 7.5e-10 38.3 2.5 4e-09 35.9 2.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX72750.1 - 0.099 11.3 2.1 4.2 6.0 1.9 3.0 2 1 0 2 2 2 0 DNA polymerase family B gpUL132 PF11359.8 EAX72750.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX72750.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Lac_bphage_repr PF06543.12 EAX72750.1 - 0.16 12.0 0.1 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAX72751.1 - 8.1e-55 184.7 7.5 9e-55 184.5 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX72753.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72753.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX72754.1 - 3.7e-157 521.0 12.8 4.6e-157 520.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72754.1 - 0.17 12.3 3.0 0.29 11.6 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX72754.1 - 0.86 10.1 5.3 5.2 7.6 0.3 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX72754.1 - 0.98 9.7 3.2 3.3 8.0 0.1 3.1 2 2 0 2 2 2 0 Rx N-terminal domain PcfK PF14058.6 EAX72755.1 - 0.043 14.1 8.5 0.067 13.5 8.5 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX72755.1 - 0.051 13.3 0.0 0.099 12.4 0.0 1.5 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX72756.1 - 4.9e-59 198.3 5.2 5.5e-59 198.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX72756.1 - 0.1 12.8 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Viral_P18 PF04521.13 EAX72757.1 - 0.024 14.4 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1493 PF07377.12 EAX72761.1 - 0.069 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX72762.1 - 0.025 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX72762.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DNA_pol_B_2 PF03175.13 EAX72763.1 - 7.2e-32 110.9 11.9 5.1e-31 108.0 11.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72763.1 - 0.04 13.9 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX72763.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) CIDR1_gamma PF18562.1 EAX72765.1 - 0.0031 17.6 1.1 0.0031 17.6 1.1 2.0 2 0 0 2 2 2 1 Cysteine-Rich Interdomain Region 1 gamma WRKY PF03106.15 EAX72765.1 - 0.015 15.5 1.5 0.045 14.0 0.1 2.2 2 0 0 2 2 2 0 WRKY DNA -binding domain PI3K_p85B PF02192.16 EAX72765.1 - 0.064 13.0 0.3 0.59 9.9 0.1 2.2 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain KilA-N PF04383.13 EAX72766.1 - 3.6e-23 81.5 0.4 4.8e-23 81.1 0.4 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72766.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin KilA-N PF04383.13 EAX72767.1 - 1e-18 67.2 0.1 1.3e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX72767.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pox_A32 PF04665.12 EAX72768.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72768.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72768.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72768.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX72769.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72769.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72769.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72769.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX72770.1 - 1.2e-60 203.6 8.0 1.3e-60 203.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX72771.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX72773.1 - 0.031 14.2 8.1 0.049 13.6 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72773.1 - 4.8 7.6 5.7 6.7 7.2 5.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX72774.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72774.1 - 0.075 12.0 0.1 0.07 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX72775.1 - 0.16 12.1 7.4 0.28 11.3 0.2 4.1 3 1 0 3 3 3 0 Phage tail repeat like TMP PF05017.14 EAX72776.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72777.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX72779.1 - 3.4e-142 472.0 14.5 4.1e-142 471.7 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX72779.1 - 0.083 12.8 0.7 0.3 10.9 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX72779.1 - 0.87 9.9 3.6 0.98 9.8 1.2 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX72779.1 - 1.3 9.6 5.4 1.1 9.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX72779.1 - 1.8 8.9 4.2 8.5 6.7 0.0 3.4 2 2 0 2 2 2 0 Rx N-terminal domain ZapB PF06005.12 EAX72779.1 - 2.3 8.7 6.1 1.8 9.0 0.4 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DDE_1 PF03184.19 EAX72781.1 - 3.4e-07 30.1 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KASH_CCD PF14662.6 EAX72782.1 - 3e-09 37.0 15.8 1.4e-06 28.3 6.1 2.1 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Laminin_I PF06008.14 EAX72782.1 - 2.8e-08 33.8 22.4 0.0031 17.3 5.2 3.2 1 1 3 4 4 4 4 Laminin Domain I CheZ PF04344.13 EAX72782.1 - 4.1e-06 26.9 15.1 0.0035 17.3 4.1 2.6 1 1 2 3 3 3 3 Chemotaxis phosphatase, CheZ DUF3552 PF12072.8 EAX72782.1 - 2e-05 24.1 5.1 0.65 9.4 1.4 3.7 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) SNAP PF14938.6 EAX72782.1 - 3.5e-05 23.4 19.8 0.00045 19.7 13.4 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP BLOC1_2 PF10046.9 EAX72782.1 - 7.1e-05 23.0 12.0 0.52 10.7 0.3 4.5 1 1 3 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 EAX72782.1 - 0.00011 22.2 11.6 0.031 14.1 2.1 2.3 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Spc7 PF08317.11 EAX72782.1 - 0.0005 19.1 16.0 0.022 13.7 10.7 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein Sec34 PF04136.15 EAX72782.1 - 0.00068 19.5 32.3 0.79 9.6 3.8 4.2 1 1 3 4 4 4 3 Sec34-like family DUF3450 PF11932.8 EAX72782.1 - 0.00069 19.0 31.9 0.016 14.5 7.7 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) DUF4686 PF15742.5 EAX72782.1 - 0.0011 18.2 18.1 0.016 14.4 7.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4686) Laminin_II PF06009.12 EAX72782.1 - 0.0012 18.8 20.1 0.29 11.2 1.9 3.2 1 1 2 3 3 3 3 Laminin Domain II UPF0449 PF15136.6 EAX72782.1 - 0.0023 18.3 15.9 2.6 8.6 1.0 4.4 1 1 3 4 4 4 1 Uncharacterised protein family UPF0449 ZapB PF06005.12 EAX72782.1 - 0.0048 17.3 9.9 1.9 9.0 1.6 4.1 1 1 3 4 4 4 1 Cell division protein ZapB DUF1664 PF07889.12 EAX72782.1 - 0.0055 16.7 8.9 1 9.4 1.0 3.0 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) TMP_2 PF06791.13 EAX72782.1 - 0.0059 16.3 35.1 1 9.0 6.5 3.4 1 1 2 3 3 3 3 Prophage tail length tape measure protein Jnk-SapK_ap_N PF09744.9 EAX72782.1 - 0.011 16.0 22.6 0.69 10.1 6.2 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 EAX72782.1 - 0.011 15.8 10.7 0.18 11.8 3.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EAX72782.1 - 0.014 15.9 19.1 1.5 9.3 1.4 3.1 1 1 3 4 4 4 0 Apg6 coiled-coil region YabA PF06156.13 EAX72782.1 - 0.016 15.9 6.4 94 3.7 6.4 3.5 1 1 0 1 1 1 0 Initiation control protein YabA BRE1 PF08647.11 EAX72782.1 - 0.016 15.2 17.7 0.52 10.4 0.9 3.3 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase GCN5L1 PF06320.13 EAX72782.1 - 0.021 15.0 12.6 2.7 8.2 0.8 3.6 1 1 3 4 4 4 0 GCN5-like protein 1 (GCN5L1) DUF4795 PF16043.5 EAX72782.1 - 0.026 14.1 18.2 1 8.9 1.7 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Prominin PF05478.11 EAX72782.1 - 0.027 12.4 19.9 0.22 9.4 4.7 2.3 1 1 1 2 2 2 0 Prominin DUF3540 PF12059.8 EAX72782.1 - 0.028 14.3 25.8 0.3 10.9 5.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3540) Serine_rich PF08824.10 EAX72782.1 - 0.036 14.1 29.2 0.8 9.7 10.3 2.8 1 1 1 2 2 2 0 Serine rich protein interaction domain ZNRF_3_ecto PF18212.1 EAX72782.1 - 0.044 13.8 6.1 9.4 6.3 0.1 3.4 1 1 1 3 3 3 0 ZNRF-3 Ectodomain DUF948 PF06103.11 EAX72782.1 - 0.047 14.0 4.4 3.7 7.9 0.4 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 EAX72782.1 - 0.066 13.4 7.6 2 8.5 2.3 2.9 1 1 2 3 3 3 0 Tropomyosin like DUF5082 PF16888.5 EAX72782.1 - 0.073 13.3 26.5 1.5 9.2 3.9 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 EAX72782.1 - 0.11 12.5 9.3 19 5.2 0.1 4.5 1 1 4 5 5 5 0 Prefoldin subunit TACC_C PF05010.14 EAX72782.1 - 0.12 12.2 11.1 0.47 10.2 6.0 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Exonuc_VII_L PF02601.15 EAX72782.1 - 0.14 11.7 31.3 1.2 8.6 12.8 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit SesA PF17107.5 EAX72782.1 - 0.14 12.3 18.0 1.2 9.3 4.6 3.0 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MCPsignal PF00015.21 EAX72782.1 - 0.18 11.6 19.3 2.6 7.8 4.5 3.1 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.11 EAX72782.1 - 0.2 12.3 23.1 6.3 7.4 2.5 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal AAA_19 PF13245.6 EAX72782.1 - 0.32 11.3 9.2 8.7e+02 0.2 9.2 3.7 1 1 0 1 1 1 0 AAA domain RNase_E_G PF10150.9 EAX72782.1 - 0.33 10.3 5.4 1.1 8.6 2.9 2.6 1 1 1 2 2 2 0 Ribonuclease E/G family TPR_MLP1_2 PF07926.12 EAX72782.1 - 0.38 10.8 35.9 0.99 9.5 19.5 3.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein CorA PF01544.18 EAX72782.1 - 0.45 9.8 18.0 0.99 8.7 2.4 3.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 EAX72782.1 - 0.5 10.6 13.2 2.1 8.5 3.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 EAX72782.1 - 0.52 10.1 13.0 1.7 8.4 1.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 EAX72782.1 - 0.97 8.6 21.8 1.6 7.9 5.8 2.9 1 1 2 3 3 3 0 TMPIT-like protein KLRAQ PF10205.9 EAX72782.1 - 1.1 9.5 6.5 43 4.4 0.4 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein H-kinase_dim PF02895.14 EAX72782.1 - 2 8.9 31.0 1.8e+04 -16.9 30.9 5.2 1 1 0 1 1 0 0 Signal transducing histidine kinase, homodimeric domain MAD PF05557.13 EAX72782.1 - 2.3 6.5 17.2 3.5 5.9 17.0 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Leu_zip PF15294.6 EAX72782.1 - 3.3 7.1 14.3 4.3 6.8 5.8 2.2 1 1 1 2 2 2 0 Leucine zipper Ribosomal_L27_C PF18471.1 EAX72782.1 - 3.5 7.0 10.4 2.7 7.3 5.4 2.3 1 1 1 2 2 2 0 Ribosomal L27 protein C-terminal domain FRB_dom PF08771.11 EAX72782.1 - 5.2 7.6 10.4 37 4.8 0.8 3.4 1 1 3 4 4 4 0 FKBP12-rapamycin binding domain HAUS-augmin3 PF14932.6 EAX72782.1 - 5.2 6.6 34.9 81 2.7 13.5 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4736 PF15883.5 EAX72782.1 - 5.5 6.7 17.0 8.7 6.0 1.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4736) Mce4_CUP1 PF11887.8 EAX72782.1 - 6.4 6.1 18.5 5.5 6.4 7.8 2.5 1 1 2 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Uso1_p115_C PF04871.13 EAX72782.1 - 6.8 7.1 42.5 1.8e+04 -21.9 42.5 3.9 1 1 0 1 1 0 0 Uso1 / p115 like vesicle tethering protein, C terminal region YojJ PF10372.9 EAX72782.1 - 7.7 6.7 25.5 9.4 6.4 0.8 5.5 1 1 5 6 6 6 0 Bacterial membrane-spanning protein N-terminus PSP PF04046.16 EAX72783.1 - 0.087 12.7 0.8 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 PSP Pox_D5 PF03288.16 EAX72785.1 - 3.2e-05 24.3 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX72786.1 - 8.6e-58 194.3 4.2 9.5e-58 194.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RRM_1 PF00076.22 EAX72787.1 - 0.011 15.5 0.8 0.016 15.0 0.8 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_1 PF00232.18 EAX72787.1 - 0.015 13.8 0.1 0.016 13.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 IBP39 PF11422.8 EAX72787.1 - 0.035 13.9 0.3 0.046 13.5 0.3 1.1 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Nup35_RRM_2 PF14605.6 EAX72787.1 - 0.13 12.3 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TMP PF05017.14 EAX72789.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72790.1 - 0.078 12.9 0.8 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 PSP DDE_Tnp_4 PF13359.6 EAX72791.1 - 1.7e-20 73.3 0.0 5e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX72791.1 - 1.2e-11 44.7 1.0 4.2e-11 42.8 1.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX72791.1 - 0.00034 20.3 1.5 0.0047 16.6 1.1 2.4 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX72791.1 - 0.04 13.4 1.3 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DDE_Tnp_1_2 PF13586.6 EAX72791.1 - 0.16 12.4 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain Ras PF00071.22 EAX72792.1 - 1.8e-52 177.2 0.1 2.1e-52 177.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX72792.1 - 3.9e-32 111.0 0.0 5.8e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX72792.1 - 1.4e-18 67.0 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX72792.1 - 7.8e-07 28.7 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX72792.1 - 2.1e-06 27.7 2.3 0.028 14.3 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX72792.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX72792.1 - 0.004 16.7 0.1 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EAX72792.1 - 0.022 14.5 0.8 0.27 11.0 0.8 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX72792.1 - 0.024 14.2 0.2 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 EAX72792.1 - 0.024 15.1 0.9 0.034 14.6 0.8 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EAX72792.1 - 0.034 13.9 0.4 0.067 12.9 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX72792.1 - 0.067 12.7 0.3 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EAX72792.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX72793.1 - 2.4e-17 62.8 0.7 5.2e-17 61.7 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX72795.1 - 4.8e-26 91.7 4.2 6.8e-26 91.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RecO_C PF02565.15 EAX72795.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal DUF2939 PF11159.8 EAX72796.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX72796.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX72796.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX72796.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX72797.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX72797.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pox_A32 PF04665.12 EAX72798.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX72798.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PTR PF12789.7 EAX72799.1 - 7.3e-09 35.6 10.5 3.6e-08 33.3 5.2 4.3 5 0 0 5 5 5 2 Phage tail repeat like GAGA_bind PF06217.12 EAX72801.1 - 0.061 13.6 4.2 0.075 13.3 4.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX72801.1 - 0.48 10.3 5.9 0.98 9.3 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX72802.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72802.1 - 6.1e-05 23.1 2.5 9.9e-05 22.4 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX72802.1 - 7.6e-05 22.5 0.3 0.28 10.9 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX72802.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72802.1 - 0.0008 19.3 0.6 0.002 18.0 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72802.1 - 0.009 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX72802.1 - 0.06 12.8 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX72802.1 - 0.069 13.6 0.1 0.41 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX72802.1 - 0.088 12.4 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX72802.1 - 0.27 11.5 4.2 8.1 6.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX72803.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_D5 PF03288.16 EAX72805.1 - 3.8e-05 24.1 2.3 0.00023 21.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX72805.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) TMP PF05017.14 EAX72806.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat RIH_assoc PF08454.11 EAX72807.1 - 0.13 12.1 0.3 0.49 10.3 0.2 2.1 1 1 1 2 2 2 0 RyR and IP3R Homology associated PTR PF12789.7 EAX72808.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.0 4 0 0 4 4 4 0 Phage tail repeat like BRO1 PF03097.18 EAX72808.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain CooT PF10133.9 EAX72809.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT PMP1_2 PF08114.11 EAX72810.1 - 0.0045 16.7 1.0 0.007 16.1 1.0 1.2 1 0 0 1 1 1 1 ATPase proteolipid family Ion_trans PF00520.31 EAX72810.1 - 0.016 14.4 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein SPC22 PF04573.12 EAX72810.1 - 0.021 14.3 0.3 0.029 13.9 0.3 1.1 1 0 0 1 1 1 0 Signal peptidase subunit FAM163 PF15069.6 EAX72810.1 - 0.049 14.1 0.0 0.052 14.0 0.0 1.2 1 0 0 1 1 1 0 FAM163 family DUF4834 PF16118.5 EAX72810.1 - 0.062 14.3 0.0 0.079 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1505 PF07403.11 EAX72810.1 - 0.066 13.4 0.1 0.081 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) DUF3169 PF11368.8 EAX72810.1 - 0.071 12.6 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) EphA2_TM PF14575.6 EAX72810.1 - 0.095 13.6 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4307 PF14155.6 EAX72810.1 - 0.14 12.0 0.2 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) TMEM132D_C PF15706.5 EAX72810.1 - 0.21 11.4 4.2 0.35 10.7 3.7 1.6 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PSP PF04046.16 EAX72811.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX72812.1 - 0.023 14.7 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX72812.1 - 0.076 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX72813.1 - 2e-33 115.8 3.1 2.3e-33 115.7 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72813.1 - 0.11 12.9 0.8 0.13 12.6 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX72814.1 - 4.7e-31 108.1 1.7 6.9e-31 107.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX72815.1 - 7.6e-07 29.6 0.2 1.9e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain DUF2897 PF11446.8 EAX72816.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_11 PF13086.6 EAX72817.1 - 0.0026 17.6 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX72817.1 - 0.0042 17.4 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72817.1 - 0.014 15.4 0.1 0.017 15.2 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX72817.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX72817.1 - 0.021 14.3 0.1 0.026 14.0 0.1 1.2 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX72817.1 - 0.04 13.5 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX72817.1 - 0.062 13.0 0.0 0.063 13.0 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX72817.1 - 0.22 11.2 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain T5orf172 PF10544.9 EAX72818.1 - 2.8e-07 31.0 0.4 5.7e-07 30.0 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX72818.1 - 0.18 12.5 0.5 0.5 11.1 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3839 PF12943.7 EAX72819.1 - 9.2e-114 378.9 7.0 1e-113 378.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX72819.1 - 0.037 13.5 0.8 0.051 13.1 0.5 1.3 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX72819.1 - 0.082 13.4 0.7 0.34 11.4 0.7 2.2 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SRP54 PF00448.22 EAX72820.1 - 0.042 13.5 1.3 1.5 8.4 0.2 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain SHIRT PF18655.1 EAX72820.1 - 0.08 13.5 0.5 0.08 13.5 0.5 3.0 3 1 1 4 4 4 0 SHIRT domain Synuclein PF01387.17 EAX72820.1 - 6.5 7.0 7.9 11 6.2 7.9 1.4 1 0 0 1 1 1 0 Synuclein PapD_N PF00345.20 EAX72821.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain JMY PF15871.5 EAX72822.1 - 0.0066 15.8 0.4 0.01 15.1 0.4 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX72822.1 - 0.13 12.3 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX72822.1 - 0.83 9.7 4.2 0.4 10.7 0.6 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF5065) GPS2_interact PF15784.5 EAX72823.1 - 0.014 15.9 0.6 0.017 15.6 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72823.1 - 0.077 12.0 0.1 0.08 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72824.1 - 0.025 14.5 8.8 0.033 14.2 8.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX72824.1 - 2 8.9 6.0 2.5 8.5 6.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AAA_22 PF13401.6 EAX72826.1 - 6.2e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72826.1 - 7.6e-05 22.8 3.1 0.00015 21.8 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72826.1 - 0.00039 20.2 0.0 0.00061 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72826.1 - 0.00088 19.1 0.9 0.0029 17.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72826.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72826.1 - 0.0079 15.9 0.4 0.19 11.5 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX72826.1 - 0.044 13.2 0.1 0.068 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX72826.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX72826.1 - 0.11 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX72826.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX72826.1 - 0.21 11.8 4.5 5.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX72827.1 - 2.9e-10 39.6 2.9 1.3e-09 37.4 2.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72827.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX72827.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 FAS_N PF17828.1 EAX72828.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72829.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72829.1 - 1.5 8.8 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX72830.1 - 0.027 14.5 3.9 0.027 14.5 3.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EAX72830.1 - 0.057 13.0 3.5 0.096 12.2 3.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit HR1 PF02185.16 EAX72830.1 - 0.097 12.8 10.6 0.47 10.6 8.5 2.9 2 1 0 2 2 2 0 Hr1 repeat Prominin PF05478.11 EAX72830.1 - 0.31 8.9 4.0 0.12 10.3 0.4 1.7 1 1 1 2 2 2 0 Prominin Laminin_II PF06009.12 EAX72830.1 - 0.41 10.6 6.9 1.1 9.3 6.9 1.8 1 1 0 1 1 1 0 Laminin Domain II Atg14 PF10186.9 EAX72830.1 - 0.49 9.4 5.7 0.65 9.0 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIVA PF05103.13 EAX72830.1 - 0.98 9.5 9.3 0.11 12.6 5.1 1.5 2 0 0 2 2 2 0 DivIVA protein DUF3552 PF12072.8 EAX72830.1 - 1.2 8.5 17.1 0.48 9.8 13.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Spc42p PF11544.8 EAX72830.1 - 1.3 9.0 14.3 0.65 10.0 2.9 2.4 1 1 0 2 2 2 0 Spindle pole body component Spc42p CENP-O PF09496.10 EAX72830.1 - 2.8 7.9 7.7 5.4 6.9 7.7 1.6 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component DUF641 PF04859.12 EAX72830.1 - 7.2 7.0 10.1 3.1 8.2 7.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMP PF05017.14 EAX72832.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX72833.1 - 3.5e-154 511.2 14.3 4.4e-154 510.9 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72833.1 - 0.27 11.7 5.8 2.2 8.8 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX72833.1 - 0.34 11.2 4.8 3 8.2 0.0 3.5 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX72833.1 - 2.3 8.8 6.0 0.92 10.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX72834.1 - 4.7e-22 78.5 4.8 6.7e-22 78.0 4.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX72834.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) KilA-N PF04383.13 EAX72835.1 - 1.8e-41 140.5 1.0 2.7e-41 139.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72835.1 - 0.019 15.6 0.1 0.05 14.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family KilA-N PF04383.13 EAX72836.1 - 4.3e-06 26.6 2.1 5.1e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX72836.1 - 0.007 17.0 0.1 0.016 15.8 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family FliJ PF02050.16 EAX72838.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein GPS2_interact PF15784.5 EAX72839.1 - 0.051 14.0 0.6 0.063 13.7 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX72839.1 - 0.087 11.8 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72840.1 - 0.24 11.4 7.1 0.27 11.2 7.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX72841.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX72842.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX72844.1 - 3.4e-30 105.3 13.4 4.3e-29 101.7 13.4 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Mito_fiss_reg PF05308.11 EAX72845.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX72845.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_D5 PF03288.16 EAX72846.1 - 2.8e-05 24.5 3.9 0.00021 21.7 3.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX72846.1 - 0.021 14.8 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX72846.1 - 0.027 15.1 0.2 0.05 14.2 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX72847.1 - 1.5e-58 196.8 8.5 1.6e-58 196.7 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX72848.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3839 PF12943.7 EAX72849.1 - 1.5e-154 512.5 14.1 1.8e-154 512.2 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72849.1 - 2.7 8.5 6.9 4 8.0 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX72851.1 - 1e-22 80.7 5.3 1.3e-22 80.3 5.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX72852.1 - 1.5e-22 80.1 4.8 1.7e-22 79.9 4.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Col_cuticle_N PF01484.17 EAX72853.1 - 0.18 11.9 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain KilA-N PF04383.13 EAX72854.1 - 1.5e-39 134.3 0.2 4.6e-39 132.7 0.2 1.9 1 1 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX72854.1 - 0.0086 16.7 0.1 0.025 15.2 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Amidase02_C PF12123.8 EAX72855.1 - 0.0099 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX72856.1 - 1.6e-07 31.8 0.5 3.2e-07 30.8 0.5 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX72857.1 - 1.3e-32 112.0 0.9 2.7e-32 110.9 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX72857.1 - 0.16 11.9 1.6 0.2 11.6 0.6 1.7 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Pox_A32 PF04665.12 EAX72858.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72858.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72858.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72858.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX72858.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX72858.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72858.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) MULE PF10551.9 EAX72860.1 - 1.8e-09 37.9 3.8 2.9e-09 37.2 3.8 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF4108 PF13390.6 EAX72862.1 - 1.2e-57 193.8 6.1 1.4e-57 193.7 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX72863.1 - 2.1e-05 24.9 2.3 0.00011 22.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72863.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX72864.1 - 1.4e-57 193.6 6.6 1.5e-57 193.5 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX72866.1 - 4.7e-110 366.8 6.7 5.3e-110 366.6 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FAS_N PF17828.1 EAX72867.1 - 0.017 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX72867.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Ank_2 PF12796.7 EAX72868.1 - 6.3e-06 26.7 0.0 7.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX72868.1 - 8.5e-05 23.0 0.0 9.4e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX72868.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX72868.1 - 0.014 15.9 0.0 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat DUF4107 PF13389.6 EAX72869.1 - 2.3e-73 245.7 4.4 2.8e-73 245.4 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX72869.1 - 0.17 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Pox_A32 PF04665.12 EAX72870.1 - 2.4e-05 23.9 3.3 2.8e-05 23.7 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX72870.1 - 0.004 17.2 1.1 0.0072 16.3 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX72870.1 - 0.06 12.6 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX72870.1 - 0.075 13.3 1.9 0.17 12.1 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX72872.1 - 2.8e-158 524.7 12.2 3.2e-158 524.5 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72872.1 - 0.43 11.1 5.8 1.7 9.2 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX72873.1 - 2.3e-152 505.3 15.8 2.8e-152 505.0 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72873.1 - 0.082 13.4 3.0 0.19 12.2 0.6 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX72873.1 - 0.22 11.4 1.9 0.55 10.1 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX72873.1 - 0.29 11.4 3.3 0.57 10.5 0.1 2.9 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX72873.1 - 0.83 10.2 7.3 2.1 8.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAS_N PF17828.1 EAX72874.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Cytadhesin_P30 PF07271.11 EAX72876.1 - 2.1 7.9 14.7 2.6 7.5 14.7 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF4378 PF14309.6 EAX72877.1 - 0.023 15.1 0.1 0.1 13.0 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX72877.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 La domain Meiosis_expr PF15163.6 EAX72879.1 - 0.035 14.8 1.0 0.052 14.2 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX72879.1 - 0.14 11.9 0.1 0.55 10.0 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX72879.1 - 1.6 8.7 11.0 0.18 11.7 2.9 2.9 4 0 0 4 4 4 0 Spo12 family DUF2939 PF11159.8 EAX72882.1 - 0.027 14.9 0.7 0.034 14.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX72882.1 - 1.8 9.3 7.9 3.9 8.1 7.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Membralin PF09746.9 EAX72882.1 - 2.2 7.2 4.5 2.4 7.1 4.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX72882.1 - 5.8 6.9 8.3 6.3 6.8 8.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX72883.1 - 0.024 14.6 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DDR PF08841.10 EAX72886.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX72886.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TPR_MLP1_2 PF07926.12 EAX72888.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX72888.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX72888.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX72890.1 - 8e-34 115.9 0.2 1e-33 115.5 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX72890.1 - 0.036 14.0 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DNA_pol_B_2 PF03175.13 EAX72891.1 - 1.3e-22 80.3 4.3 1.7e-22 79.9 4.3 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX72891.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX72892.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Como_SCP PF02248.16 EAX72895.1 - 0.17 11.4 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Small coat protein DUF3839 PF12943.7 EAX72896.1 - 3.4e-73 246.1 8.2 4.3e-73 245.7 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX72896.1 - 0.24 12.0 2.9 0.45 11.1 2.9 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr T5orf172 PF10544.9 EAX72897.1 - 8.6e-05 23.0 0.8 0.00024 21.6 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX72897.1 - 0.0076 15.8 0.5 0.11 12.0 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX72897.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX72897.1 - 0.072 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX72898.1 - 3e-07 30.1 2.4 3e-07 30.1 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX72898.1 - 3.5e-05 24.1 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX72898.1 - 3.6e-05 23.6 0.2 0.4 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX72898.1 - 0.00015 21.8 3.7 0.00037 20.5 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72898.1 - 0.00041 20.2 0.1 0.00078 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72898.1 - 0.0011 18.8 0.6 0.0019 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX72898.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX72898.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX72898.1 - 0.073 12.6 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX72898.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX72898.1 - 0.088 12.2 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX72898.1 - 0.096 13.1 0.1 0.78 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX72898.1 - 0.41 10.9 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) RRM_1 PF00076.22 EAX72899.1 - 9.8e-17 60.5 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX72899.1 - 3.4e-08 33.1 0.0 3.9e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX72899.1 - 2.6e-06 27.2 0.0 3.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EAX72899.1 - 0.00038 20.4 0.0 0.00049 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 EAX72899.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.3 1 1 0 1 1 1 1 Limkain b1 DapH_N PF08503.10 EAX72899.1 - 0.087 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal DNA_pol_B_2 PF03175.13 EAX72900.1 - 2.2e-11 43.3 3.0 2.1e-10 40.1 2.4 2.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DDE_Tnp_4 PF13359.6 EAX72901.1 - 1.2e-31 109.5 0.0 1.6e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX72901.1 - 1.1e-08 35.0 0.1 5.6e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain DUF3839 PF12943.7 EAX72902.1 - 4.3e-40 137.7 4.5 6e-40 137.2 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX72902.1 - 0.089 13.4 0.2 0.1 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) GalP_UDP_transf PF01087.22 EAX72902.1 - 0.25 11.7 1.7 0.87 10.0 0.9 1.8 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain HTH_32 PF13565.6 EAX72904.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PhaP_Bmeg PF09602.10 EAX72905.1 - 0.026 14.5 0.1 0.37 10.7 0.1 2.1 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Homez PF11569.8 EAX72905.1 - 0.22 11.0 0.5 0.44 10.1 0.5 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez T5orf172 PF10544.9 EAX72907.1 - 8.7e-05 23.0 0.3 0.00025 21.5 0.3 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX72907.1 - 0.0096 15.5 1.0 0.11 12.0 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX72907.1 - 0.027 14.3 2.0 0.061 13.2 0.5 2.3 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX72908.1 - 4.2e-24 85.3 3.0 6.2e-24 84.8 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX72909.1 - 3.9e-07 29.8 3.4 5.4e-07 29.3 3.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72909.1 - 0.0045 16.6 0.2 0.0058 16.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX72909.1 - 0.022 14.5 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX72909.1 - 0.057 13.2 0.2 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX72909.1 - 0.058 12.9 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF3783 PF12646.7 EAX72909.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72909.1 - 0.62 10.3 8.5 5.4 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PapD_N PF00345.20 EAX72912.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72912.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX72913.1 - 1.1e-12 47.8 1.2 2e-12 46.9 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX72914.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Imm70 PF15601.6 EAX72915.1 - 0.15 11.6 3.1 7.2 6.2 0.2 2.7 1 1 3 4 4 4 0 Immunity protein 70 DUF3839 PF12943.7 EAX72917.1 - 9.8e-117 388.6 12.4 3.3e-116 386.9 12.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72917.1 - 0.082 13.4 3.6 0.44 11.0 0.7 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX72919.1 - 7.9e-62 207.4 5.9 8.8e-62 207.3 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX72920.1 - 6.8e-131 435.0 11.8 1.1e-130 434.4 11.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX72920.1 - 0.011 16.2 3.0 0.011 16.2 0.6 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX72920.1 - 0.62 10.6 6.4 5.4 7.6 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX72921.1 - 7.2e-23 81.2 4.7 9.2e-23 80.8 4.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4108 PF13390.6 EAX72923.1 - 3.3e-58 195.7 4.5 3.6e-58 195.5 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX72923.1 - 0.09 13.0 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DDR PF08841.10 EAX72924.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX72926.1 - 3.2e-31 107.2 19.1 7e-28 96.5 11.2 3.9 4 1 1 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX72926.1 - 0.095 13.3 13.7 0.86 10.2 0.1 3.4 2 1 0 2 2 2 0 YmaF family DUF240 PF03086.14 EAX72926.1 - 0.48 10.4 5.7 1.8 8.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Pho88 PF10032.9 EAX72926.1 - 7.9 5.7 6.8 1.8 7.8 0.8 2.1 2 0 0 2 2 2 0 Phosphate transport (Pho88) DUF4108 PF13390.6 EAX72928.1 - 1.2e-57 193.9 7.3 1.3e-57 193.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX72928.1 - 0.12 12.6 0.1 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX72929.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain FAS_N PF17828.1 EAX72930.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72931.1 - 0.016 15.6 0.7 0.02 15.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72931.1 - 5.6 7.0 6.3 6.3 6.8 6.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX72933.1 - 2.7e-120 400.3 10.8 3.4e-120 400.0 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72933.1 - 0.053 14.0 1.2 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX72935.1 - 3.4e-26 92.6 25.0 3.8e-26 92.5 25.0 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4106 PF13388.6 EAX72936.1 - 1.7e-206 686.4 17.7 2e-206 686.2 17.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX72936.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF737 PF05300.11 EAX72936.1 - 2.3 8.5 14.3 0.38 11.1 5.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF737) Ndc1_Nup PF09531.10 EAX72936.1 - 3.3 6.3 3.8 5.4 5.6 3.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMP PF05017.14 EAX72937.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72938.1 - 0.057 13.3 0.5 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2897 PF11446.8 EAX72939.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX72940.1 - 5.2e-05 23.5 0.1 0.00023 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72940.1 - 5.3e-05 23.3 2.1 9.4e-05 22.5 2.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX72940.1 - 9e-05 22.3 0.2 0.24 11.1 0.0 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX72940.1 - 0.00043 20.1 0.0 0.00057 19.7 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX72940.1 - 0.0012 18.6 0.3 0.0033 17.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72940.1 - 0.0094 16.3 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX72940.1 - 0.059 12.8 0.0 0.086 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX72940.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72940.1 - 0.1 13.0 0.0 0.42 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX72940.1 - 0.34 11.2 3.8 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX72942.1 - 7.7e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX72942.1 - 0.06 13.5 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers DNA_pol_B_2 PF03175.13 EAX72943.1 - 8.2e-10 38.1 2.8 3.2e-09 36.2 2.8 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72943.1 - 0.15 12.1 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF4107 PF13389.6 EAX72946.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Csm1_N PF18504.1 EAX72947.1 - 0.00019 21.7 4.4 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX72947.1 - 0.00068 19.7 9.1 0.0033 17.5 9.2 1.9 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 EAX72947.1 - 0.0027 18.1 3.7 0.0044 17.4 3.7 1.4 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX72947.1 - 0.0041 16.1 4.7 0.0047 15.9 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX72947.1 - 0.0054 16.5 5.5 0.0072 16.2 1.4 2.9 1 1 2 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX72947.1 - 0.0063 16.8 4.0 0.0095 16.3 4.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 EAX72947.1 - 0.013 15.7 6.2 0.016 15.4 6.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EAX72947.1 - 0.013 15.4 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HemX PF04375.14 EAX72947.1 - 0.018 14.4 4.0 0.022 14.0 4.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 EAX72947.1 - 0.025 13.7 3.8 0.025 13.7 3.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EAX72947.1 - 0.027 14.5 7.4 0.043 13.9 7.2 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 EAX72947.1 - 0.028 13.8 4.9 0.033 13.5 4.9 1.1 1 0 0 1 1 1 0 FAM76 protein GNT-I PF03071.15 EAX72947.1 - 0.043 12.6 0.9 0.058 12.2 0.9 1.1 1 0 0 1 1 1 0 GNT-I family ATG16 PF08614.11 EAX72947.1 - 0.083 13.1 10.7 0.11 12.7 10.7 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EAX72947.1 - 0.092 12.5 7.4 1.2 8.9 4.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 EAX72947.1 - 0.11 11.8 3.2 0.13 11.5 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 EAX72947.1 - 0.49 10.5 6.6 31 4.8 0.0 2.5 1 1 0 2 2 2 0 bZIP transcription factor COMP PF11598.8 EAX72947.1 - 0.98 9.9 5.8 2.3 8.7 3.1 2.2 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 EAX72947.1 - 2.2 8.1 8.5 2 8.2 3.6 2.2 1 1 1 2 2 2 0 Septum formation initiator KilA-N PF04383.13 EAX72948.1 - 9.2e-33 112.4 0.8 2.1e-32 111.3 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX72948.1 - 0.0052 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) MuF_C PF18819.1 EAX72948.1 - 0.046 13.7 0.5 0.095 12.7 0.5 1.5 1 0 0 1 1 1 0 Phage MuF-C-terminal domain DDR PF08841.10 EAX72949.1 - 0.16 10.9 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX72950.1 - 0.011 15.7 15.2 0.016 15.2 15.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC27 PF09507.10 EAX72950.1 - 5.3 6.3 12.3 6.9 5.9 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PapD_N PF00345.20 EAX72951.1 - 0.057 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX72951.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family YmaF PF12788.7 EAX72953.1 - 0.17 12.5 2.0 2.7 8.6 2.0 2.1 1 1 1 2 2 2 0 YmaF family Pox_D5 PF03288.16 EAX72954.1 - 3.7e-05 24.1 2.6 0.00027 21.4 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX72954.1 - 0.074 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX72955.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX72956.1 - 2.8 7.9 6.6 1.7 8.6 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX72957.1 - 2.9e-52 174.6 28.3 1.7e-32 111.3 14.8 4.4 4 1 1 5 5 5 2 Phage tail repeat like Pox_A32 PF04665.12 EAX72958.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72958.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX72958.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX72958.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72958.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72958.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) GAGA_bind PF06217.12 EAX72959.1 - 0.42 10.9 15.6 0.46 10.7 15.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4551 PF15087.6 EAX72959.1 - 1.6 7.4 11.5 1.6 7.5 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4407 PF14362.6 EAX72959.1 - 1.6 8.0 12.7 1.8 7.9 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 EAX72959.1 - 4.1 6.1 11.2 4.1 6.1 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5365 PF17326.2 EAX72961.1 - 0.03 14.7 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX72961.1 - 0.042 14.2 0.4 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF445 PF04286.12 EAX72962.1 - 0.018 14.9 3.5 0.029 14.2 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX72962.1 - 0.049 14.1 1.9 0.14 12.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF1902 PF08972.11 EAX72962.1 - 0.06 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) RNA_pol_Rpb8 PF03870.15 EAX72962.1 - 0.092 12.9 1.4 0.16 12.2 1.4 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 Nsp1_C PF05064.13 EAX72962.1 - 0.18 11.6 3.6 2.9 7.7 0.1 3.3 3 1 1 4 4 4 0 Nsp1-like C-terminal region DUF4107 PF13389.6 EAX72963.1 - 1e-72 243.6 3.7 1.4e-72 243.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX72963.1 - 0.074 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX72964.1 - 9.3e-10 38.0 1.9 1.3e-09 37.4 1.2 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX72965.1 - 0.018 14.3 0.5 0.029 13.7 0.5 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein 2_5_RNA_ligase2 PF13563.6 EAX72965.1 - 0.12 12.2 0.0 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily DUF3839 PF12943.7 EAX72966.1 - 4e-80 268.8 11.1 5.3e-80 268.4 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX72966.1 - 0.085 12.4 0.5 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX72966.1 - 0.11 13.1 0.5 0.17 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX72968.1 - 1.5e-05 24.6 1.6 1.8e-05 24.3 1.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72968.1 - 0.0035 17.0 0.2 0.005 16.5 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72968.1 - 0.035 13.8 0.3 0.19 11.4 0.1 2.1 1 1 2 3 3 3 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX72968.1 - 0.038 13.5 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF3783 PF12646.7 EAX72968.1 - 0.09 12.8 2.2 0.98 9.4 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX72968.1 - 0.21 11.8 7.4 3.9 7.7 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) APG12 PF04110.13 EAX72968.1 - 0.22 12.0 2.2 0.31 11.5 1.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 KilA-N PF04383.13 EAX72970.1 - 5.2e-17 61.7 0.2 5.2e-17 61.7 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX72970.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX72970.1 - 0.13 10.8 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX72971.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX72971.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX72971.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX72971.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX72972.1 - 1.7 8.6 4.8 3.5 7.6 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX72973.1 - 1.9e-43 147.8 3.7 2.1e-43 147.7 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX72973.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein TMP PF05017.14 EAX72974.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX72975.1 - 3.3e-154 511.4 11.8 4.1e-154 511.0 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX72975.1 - 1.9 9.0 5.8 3.4 8.2 0.7 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX72976.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX72978.1 - 3e-15 56.7 1.2 3.5e-15 56.5 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX72979.1 - 0.22 12.2 4.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX72980.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX72981.1 - 2.2e-17 62.9 0.1 4.4e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF1493 PF07377.12 EAX72982.1 - 0.068 13.6 0.5 0.16 12.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX72983.1 - 5.6e-07 29.3 4.0 5.6e-07 29.3 4.0 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX72983.1 - 4.5e-05 23.3 0.2 0.38 10.5 0.0 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX72983.1 - 6.1e-05 23.3 0.2 0.00049 20.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX72983.1 - 0.00014 22.0 2.6 0.00031 20.8 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX72983.1 - 0.00042 20.1 0.1 0.00075 19.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX72983.1 - 0.0012 18.5 0.6 0.0077 15.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX72983.1 - 0.0024 17.7 0.5 0.0043 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX72983.1 - 0.012 15.9 0.0 0.041 14.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain DUF2805 PF10985.8 EAX72983.1 - 0.057 13.8 1.6 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) AAA_25 PF13481.6 EAX72983.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX72983.1 - 0.095 13.1 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX72983.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX72983.1 - 0.43 10.9 3.5 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) FAS_N PF17828.1 EAX72984.1 - 0.009 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72985.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX72985.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX72988.1 - 7.5e-107 349.4 90.6 1.6e-30 105.0 20.0 6.3 4 2 3 7 7 7 5 Phage tail repeat like RACo_linker PF17650.1 EAX72988.1 - 0.0054 16.6 0.5 1.9 8.4 0.1 3.5 2 1 2 4 4 4 1 RACo linker region PH_TFIIH PF08567.11 EAX72988.1 - 0.073 13.4 12.4 2.6 8.4 0.2 5.0 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain Peptidase_C78 PF07910.13 EAX72988.1 - 0.11 12.0 2.8 2.2 7.7 0.3 3.0 1 1 2 3 3 3 0 Peptidase family C78 SAS4 PF15460.6 EAX72988.1 - 0.11 12.5 12.6 15 5.7 0.1 3.7 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF4116 PF13475.6 EAX72988.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GUN4_N PF16416.5 EAX72988.1 - 0.18 11.9 4.5 9.8 6.3 0.2 3.5 1 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal DUF1493 PF07377.12 EAX72989.1 - 0.021 15.3 0.5 0.04 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX72989.1 - 0.5 10.4 3.6 11 6.2 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX72990.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX72991.1 - 0.033 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) VirE PF05272.11 EAX72992.1 - 0.0087 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX72992.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX72992.1 - 0.1 11.5 0.2 9.3 5.0 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FAS_N PF17828.1 EAX72994.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX72995.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX72995.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX72995.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX72996.1 - 0.024 15.1 0.4 0.045 14.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX72996.1 - 0.15 12.1 1.7 8.9 6.4 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DNA_pol_B_2 PF03175.13 EAX72999.1 - 3.7e-09 36.0 1.6 5.4e-09 35.4 0.8 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX72999.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX73000.1 - 1.3e-152 506.1 12.1 1.5e-152 506.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX73000.1 - 0.31 11.3 3.4 2.1 8.7 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX73000.1 - 0.34 11.4 7.3 1.7 9.1 1.0 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX73001.1 - 4.6e-23 81.8 4.3 6.4e-23 81.3 4.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PSP PF04046.16 EAX73002.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX73003.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat GPS2_interact PF15784.5 EAX73004.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73004.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX73005.1 - 0.03 14.3 8.3 0.047 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX73005.1 - 3.7 8.0 5.1 5.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4108 PF13390.6 EAX73007.1 - 1.5e-60 203.2 9.0 1.7e-60 203.1 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX73008.1 - 0.049 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX73008.1 - 1.5 8.7 3.8 3.2 7.7 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GPS2_interact PF15784.5 EAX73010.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73010.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAX73012.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_D5 PF03288.16 EAX73013.1 - 1.8e-05 25.1 0.3 2.9e-05 24.5 0.3 1.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73013.1 - 0.011 16.4 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73013.1 - 0.026 14.5 0.3 0.038 14.0 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3781 PF12636.7 EAX73015.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX73016.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73016.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX73016.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase PSP PF04046.16 EAX73017.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73018.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX73019.1 - 0.025 15.1 0.7 0.046 14.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX73020.1 - 4.5e-07 29.6 2.7 7.5e-07 28.8 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73020.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73020.1 - 0.055 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73020.1 - 0.063 13.0 0.1 0.27 11.0 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73020.1 - 0.097 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73020.1 - 0.1 12.6 2.2 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX73020.1 - 0.13 12.7 3.2 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX73020.1 - 0.43 10.8 8.5 5.4 7.2 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) TPR_2 PF07719.17 EAX73021.1 - 0.005 16.8 0.3 1.2 9.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX73021.1 - 0.11 12.3 0.9 16 5.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HNH_3 PF13392.6 EAX73022.1 - 1.1e-06 28.2 0.1 2.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Tim54 PF11711.8 EAX73022.1 - 0.003 16.4 0.9 0.0041 15.9 0.9 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF1840 PF08895.11 EAX73022.1 - 0.0068 16.7 2.5 0.0068 16.7 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1840) DUF4746 PF15928.5 EAX73022.1 - 0.01 15.3 10.8 0.012 15.0 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 EAX73022.1 - 0.091 13.0 9.2 0.12 12.7 9.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1682 PF07946.14 EAX73022.1 - 0.096 11.9 5.0 0.12 11.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NOA36 PF06524.12 EAX73022.1 - 0.2 10.9 5.9 0.28 10.5 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein RabGAP-TBC PF00566.18 EAX73022.1 - 0.33 10.6 2.7 0.89 9.2 0.5 2.0 2 0 0 2 2 2 0 Rab-GTPase-TBC domain AATF-Che1 PF13339.6 EAX73022.1 - 0.34 11.6 4.0 0.52 11.0 3.7 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Radial_spoke PF04712.12 EAX73022.1 - 0.38 9.7 15.2 0.065 12.2 11.3 1.6 2 0 0 2 2 2 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 EAX73022.1 - 0.62 8.1 11.8 0.87 7.6 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EAX73022.1 - 1.3 8.2 5.8 2 7.6 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF740 PF05340.12 EAX73022.1 - 3 6.5 7.5 3.8 6.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2457 PF10446.9 EAX73022.1 - 9.2 5.3 12.9 13 4.8 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_A32 PF04665.12 EAX73023.1 - 2.8e-07 30.2 2.9 3.9e-07 29.8 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73023.1 - 0.0045 16.6 0.1 0.006 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73023.1 - 0.056 12.9 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73023.1 - 0.063 13.0 0.3 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73023.1 - 0.2 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73023.1 - 0.51 10.5 8.3 5.7 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX73025.1 - 6.8e-63 210.9 6.4 7.6e-63 210.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX73027.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73027.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73027.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73027.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73027.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73027.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73027.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX73028.1 - 5.8e-16 58.7 3.3 8.8e-16 58.1 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX73028.1 - 0.15 12.5 0.5 0.39 11.2 0.2 1.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF4106 PF13388.6 EAX73030.1 - 5.1e-161 536.6 19.6 5.1e-161 536.6 19.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX73030.1 - 0.55 8.8 3.0 0.84 8.2 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_22 PF13401.6 EAX73032.1 - 6.3e-05 23.3 0.0 0.00032 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX73032.1 - 7e-05 22.9 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73032.1 - 0.00038 20.3 0.0 0.00051 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73032.1 - 0.0013 18.6 1.6 0.0044 16.8 1.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73032.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX73032.1 - 0.009 15.8 0.3 0.19 11.5 0.0 2.3 1 1 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX73032.1 - 0.043 13.3 0.1 0.069 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX73032.1 - 0.075 12.8 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX73032.1 - 0.11 12.9 0.0 0.36 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX73032.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX73032.1 - 0.17 12.2 4.2 5 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX73034.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX73035.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73035.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73035.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73035.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_D5 PF03288.16 EAX73037.1 - 0.0001 22.7 1.5 0.00016 22.1 1.5 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73037.1 - 0.001 19.6 0.1 0.0016 19.0 0.1 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73037.1 - 0.024 14.6 1.1 0.044 13.7 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Adeno_52K PF03052.15 EAX73037.1 - 0.15 11.5 0.1 0.79 9.1 0.1 1.8 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa Pox_D5 PF03288.16 EAX73038.1 - 2.4e-05 24.7 2.5 0.00012 22.5 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73038.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF1493 PF07377.12 EAX73040.1 - 0.0087 16.5 0.8 0.019 15.5 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX73043.1 - 6.5e-25 87.9 10.9 2.5e-24 86.0 10.9 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73043.1 - 0.11 12.5 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX73043.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 ETRAMP PF09716.10 EAX73044.1 - 0.033 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4690 PF15756.5 EAX73044.1 - 0.044 14.4 0.1 0.076 13.6 0.1 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TMEM51 PF15345.6 EAX73044.1 - 0.052 13.4 0.1 0.078 12.8 0.0 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 YlaH PF14036.6 EAX73044.1 - 0.075 13.4 0.2 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 YlaH-like protein TALPID3 PF15324.6 EAX73044.1 - 0.42 8.2 7.5 0.51 8.0 7.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target SLAIN PF15301.6 EAX73044.1 - 0.52 9.5 5.3 20 4.3 6.5 2.0 2 0 0 2 2 2 0 SLAIN motif-containing family Hamartin PF04388.12 EAX73044.1 - 2.2 6.8 6.5 2.7 6.6 6.5 1.1 1 0 0 1 1 1 0 Hamartin protein Pox_D5 PF03288.16 EAX73045.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73045.1 - 0.071 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX73046.1 - 6.3e-65 217.5 5.9 7e-65 217.3 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73046.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF3417 PF11897.8 EAX73047.1 - 0.11 13.0 0.4 0.14 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX73047.1 - 0.3 11.0 2.0 0.51 10.3 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PadR PF03551.14 EAX73048.1 - 0.12 12.4 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX73049.1 - 0.031 14.7 0.4 0.035 14.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4107 PF13389.6 EAX73050.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73050.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX73052.1 - 2.6e-40 136.7 0.5 6.7e-40 135.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX73052.1 - 0.32 11.0 2.6 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF4378 PF14309.6 EAX73053.1 - 0.06 13.7 0.0 0.26 11.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) DUF2294 PF10057.9 EAX73055.1 - 0.00058 20.0 9.4 1.8 8.7 0.3 3.5 1 1 3 4 4 4 3 Uncharacterized conserved protein (DUF2294) DUF1935 PF09149.10 EAX73055.1 - 0.006 17.0 11.2 0.046 14.1 2.7 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1935) ETF PF01012.21 EAX73055.1 - 0.02 14.8 10.6 0.17 11.8 3.8 2.3 1 1 2 3 3 3 0 Electron transfer flavoprotein domain FAM219A PF15260.6 EAX73055.1 - 0.029 14.7 10.9 2.8 8.3 1.2 3.2 1 1 2 3 3 3 0 Protein family FAM219A Fucose_iso_C PF02952.17 EAX73055.1 - 0.074 12.8 2.7 0.25 11.0 0.3 2.3 1 1 2 3 3 3 0 L-fucose isomerase, C-terminal domain MlaD PF02470.20 EAX73055.1 - 0.15 12.4 9.9 1.8 8.9 0.8 3.5 1 1 2 3 3 3 0 MlaD protein DUF749 PF05370.11 EAX73055.1 - 0.25 11.5 6.8 3.8 7.7 1.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF749) DsbC PF11412.8 EAX73055.1 - 0.33 11.0 11.5 4.1 7.5 0.1 3.9 4 0 0 4 4 4 0 Disulphide bond corrector protein DsbC Golgin_A5 PF09787.9 EAX73055.1 - 0.37 10.2 21.8 0.44 10.0 21.8 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 AlkA_N PF06029.11 EAX73055.1 - 0.46 10.8 3.3 9.8 6.5 1.0 2.3 1 1 2 3 3 3 0 AlkA N-terminal domain PS-DH PF14765.6 EAX73055.1 - 0.72 9.0 14.2 1.9 7.6 6.5 2.0 1 1 1 2 2 2 0 Polyketide synthase dehydratase Tail_tube PF10618.9 EAX73055.1 - 0.92 9.4 9.2 1.2 9.0 3.4 2.1 1 1 1 2 2 2 0 Phage tail tube protein DUF2584 PF10763.9 EAX73055.1 - 1.9 8.7 8.5 18 5.6 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2584) DUF4884 PF16225.5 EAX73055.1 - 3 8.0 10.2 67 3.7 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4884) MerB PF03243.15 EAX73055.1 - 4.3 7.5 16.6 5.1 7.3 3.9 2.7 1 1 2 3 3 3 0 Alkylmercury lyase SURF2 PF05477.11 EAX73055.1 - 4.8 6.8 14.2 5.4 6.6 3.3 1.8 1 1 1 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF2031 PF09592.10 EAX73055.1 - 5.4 6.5 12.3 6 6.3 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) DUF2550 PF10739.9 EAX73055.1 - 6.1 6.9 5.5 25 4.9 0.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2550) MG1 PF17790.1 EAX73055.1 - 8.2 6.9 17.9 4 7.9 11.2 2.1 1 1 1 2 2 2 0 Macroglobulin domain MG1 T5orf172 PF10544.9 EAX73056.1 - 1.2e-06 29.0 0.3 2.2e-06 28.1 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF5460 PF17544.2 EAX73057.1 - 0.03 13.3 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5460) SPC25 PF06703.11 EAX73057.1 - 0.091 12.5 0.5 0.11 12.3 0.5 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4108 PF13390.6 EAX73058.1 - 3.3e-58 195.7 7.3 3.7e-58 195.5 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX73060.1 - 3.6e-10 39.3 2.0 2.1e-09 36.8 2.0 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX73062.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73062.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX73063.1 - 1.2e-24 87.1 11.3 4.9e-24 85.0 11.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73063.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4106 PF13388.6 EAX73064.1 - 3.4e-197 655.8 46.2 4e-118 395.3 15.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.10 EAX73064.1 - 1.9 7.1 15.5 3 6.4 15.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4108 PF13390.6 EAX73066.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX73066.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Phage_fiber PF03335.13 EAX73068.1 - 5 7.6 6.9 23 5.5 1.8 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat Amidase02_C PF12123.8 EAX73069.1 - 0.0042 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX73070.1 - 9.1e-34 115.7 0.2 3.1e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF2897 PF11446.8 EAX73071.1 - 0.61 10.0 2.9 1.2 9.1 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) SH3BGR PF04908.15 EAX73071.1 - 0.85 9.8 4.3 0.71 10.1 3.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF4108 PF13390.6 EAX73072.1 - 3.3e-51 173.0 5.3 3.7e-51 172.8 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX73073.1 - 4.8e-52 173.9 38.2 4e-33 113.3 16.2 4.8 3 2 3 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX73073.1 - 0.096 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX73075.1 - 5.6e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX73075.1 - 0.17 12.4 1.1 0.34 11.4 0.5 1.7 1 1 1 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX73076.1 - 6.3e-08 32.4 0.6 7e-08 32.2 0.6 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73076.1 - 0.0068 16.1 0.1 0.0071 16.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX73076.1 - 0.057 13.4 0.4 0.53 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX73076.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1493 PF07377.12 EAX73078.1 - 0.084 13.3 0.7 0.18 12.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX73079.1 - 0.074 13.7 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX73080.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX73080.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX73080.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX73081.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX73083.1 - 5.5e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX73083.1 - 0.046 13.8 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers Pox_A32 PF04665.12 EAX73084.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73084.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73084.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73084.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73084.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73084.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73084.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX73085.1 - 5.2e-63 211.3 6.0 5.7e-63 211.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RNA_polI_A34 PF08208.11 EAX73086.1 - 0.35 10.9 17.0 0.42 10.7 17.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3464 PF11947.8 EAX73086.1 - 8.9 6.1 6.5 9.9 5.9 5.8 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX73086.1 - 9.8 6.1 8.2 20 5.1 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX73089.1 - 2.9e-25 88.3 1.5 4e-25 87.8 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX73089.1 - 0.0049 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Ycf34 PF10718.9 EAX73089.1 - 0.24 12.1 1.3 48 4.7 0.1 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX73090.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73090.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73090.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73090.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX73092.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX73093.1 - 0.32 11.4 1.6 0.38 11.1 1.6 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX73093.1 - 0.49 10.3 2.7 0.87 9.5 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73094.1 - 9.6e-48 161.7 6.1 1.1e-47 161.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FAR1 PF03101.15 EAX73096.1 - 0.014 16.1 0.1 0.029 15.1 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain KilA-N PF04383.13 EAX73097.1 - 1.9e-32 111.4 0.6 4.2e-32 110.3 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73097.1 - 0.01 16.5 0.1 0.027 15.1 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family DUF2344 PF10105.9 EAX73097.1 - 0.065 13.1 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) HNH_3 PF13392.6 EAX73098.1 - 1.2e-07 31.4 0.3 2.1e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3839 PF12943.7 EAX73099.1 - 1.7e-07 30.9 1.6 1.7e-07 30.9 1.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX73099.1 - 0.032 14.5 0.1 0.052 13.8 0.1 1.5 1 1 0 1 1 1 0 PRD domain FAS_N PF17828.1 EAX73100.1 - 0.009 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73101.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73101.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX73101.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX73101.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX73102.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF1493 PF07377.12 EAX73103.1 - 0.0072 16.8 1.9 0.0081 16.6 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73103.1 - 0.68 10.0 4.6 8.6 6.5 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX73105.1 - 3e-05 23.6 3.1 3.4e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX73105.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX73105.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX73105.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX73106.1 - 3e-84 282.3 7.8 3.5e-84 282.0 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73106.1 - 0.032 13.7 0.3 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX73107.1 - 7.2e-11 41.9 0.2 1.4e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX73107.1 - 0.22 10.9 0.2 0.53 9.7 0.2 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX73108.1 - 2.3e-155 515.1 12.5 2.8e-155 514.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX73108.1 - 0.013 15.9 1.6 0.066 13.7 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX73108.1 - 0.12 12.8 5.6 1.6 9.3 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Val_tRNA-synt_C PF10458.9 EAX73108.1 - 0.16 12.3 1.8 0.3 11.4 0.5 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PRD PF00874.20 EAX73108.1 - 0.31 11.4 3.3 0.8 10.0 0.1 3.0 2 2 1 3 3 3 0 PRD domain Amidase02_C PF12123.8 EAX73109.1 - 0.0098 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX73110.1 - 8e-37 126.9 2.8 8.6e-37 126.8 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73110.1 - 0.046 14.1 0.1 0.074 13.4 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX73111.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73111.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73111.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73111.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73111.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73111.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73111.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX73112.1 - 2.5e-07 31.2 0.2 4.7e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX73113.1 - 3.6e-94 314.7 6.8 4.1e-94 314.6 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX73114.1 - 1.6e-05 24.8 1.0 1.6e-05 24.8 1.0 3.9 4 1 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX73114.1 - 0.016 15.0 3.6 0.022 14.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MeaB PF03308.16 EAX73114.1 - 0.071 12.1 0.5 0.12 11.3 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX73114.1 - 0.3 11.6 2.6 0.72 10.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX73114.1 - 1.9 8.0 15.4 0.56 9.8 6.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) VirE PF05272.11 EAX73115.1 - 0.0083 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX73115.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX73115.1 - 0.08 11.8 0.2 7.2 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TMP PF05017.14 EAX73118.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73119.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73120.1 - 0.03 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73121.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX73122.1 - 2.9e-66 222.6 13.3 1.4e-64 217.1 13.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73122.1 - 0.063 13.6 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TMP PF05017.14 EAX73123.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX73125.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73125.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73125.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73125.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73125.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73125.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73125.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX73127.1 - 3.8e-158 524.2 13.5 4.5e-158 524.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX73127.1 - 0.12 12.8 0.4 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX73127.1 - 0.73 10.3 7.6 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73129.1 - 7.3e-155 513.5 11.1 9.2e-155 513.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73129.1 - 0.081 12.8 0.7 0.23 11.3 0.7 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX73129.1 - 0.39 11.0 4.1 2.1 8.7 0.0 3.3 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX73129.1 - 1.6 9.2 5.0 3.8 8.0 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73130.1 - 8.6e-144 477.2 14.1 1e-143 476.9 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX73130.1 - 0.12 12.7 0.8 0.45 10.8 0.2 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit APC_u14 PF16635.5 EAX73130.1 - 0.35 11.4 2.6 0.95 10.0 2.6 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DUF2897 PF11446.8 EAX73131.1 - 0.028 14.3 2.1 0.038 13.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73132.1 - 4.2e-62 208.3 6.8 4.7e-62 208.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73133.1 - 0.00012 22.5 2.3 0.00066 20.1 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73133.1 - 0.038 14.6 0.1 0.078 13.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73133.1 - 0.072 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Ank_2 PF12796.7 EAX73134.1 - 5.2e-16 59.0 0.0 4.5e-07 30.4 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX73134.1 - 1.7e-11 43.3 0.0 0.00041 20.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX73134.1 - 8.4e-10 38.7 0.0 9.3e-05 22.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX73134.1 - 8.9e-10 38.9 0.0 1.8e-06 28.4 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX73134.1 - 2.5e-09 37.2 0.0 0.0013 19.0 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FlgM PF04316.13 EAX73134.1 - 0.027 14.8 0.1 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM L_protein_N PF15518.6 EAX73134.1 - 0.036 13.9 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 L protein N-terminus DUF4108 PF13390.6 EAX73135.1 - 3.8e-52 176.0 6.7 4.2e-52 175.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73136.1 - 6.2e-05 23.4 3.0 0.00042 20.7 3.0 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX73138.1 - 1e-64 216.8 6.2 1.1e-64 216.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX73139.1 - 2.1e-75 253.3 10.4 2.8e-75 252.9 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX73139.1 - 0.047 14.1 0.3 0.056 13.9 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF3839 PF12943.7 EAX73140.1 - 5.4e-158 523.7 13.9 6.6e-158 523.4 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73140.1 - 1.3 9.5 7.5 2.1 8.8 0.5 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX73141.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX73142.1 - 6.7e-07 29.8 0.5 2.2e-06 28.1 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX73142.1 - 0.11 12.3 1.2 0.47 10.3 0.3 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX73142.1 - 0.18 11.3 0.3 2.5 7.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain FLYWCH PF04500.16 EAX73143.1 - 0.034 14.2 3.9 0.058 13.5 3.9 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX73143.1 - 0.053 14.2 1.0 0.14 12.9 1.0 1.7 1 1 0 1 1 1 0 FAR1 DNA-binding domain Ank_2 PF12796.7 EAX73144.1 - 2.1e-41 140.4 19.5 4.7e-13 49.5 0.3 5.1 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX73144.1 - 3.9e-41 137.7 15.7 4.7e-08 33.1 0.2 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX73144.1 - 1.6e-40 137.0 15.2 3.4e-13 49.8 0.3 6.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX73144.1 - 2.4e-37 122.7 16.9 8.4e-07 28.8 0.0 8.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX73144.1 - 2.2e-27 94.7 9.6 3.2e-09 36.9 0.2 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX73144.1 - 1.5e-18 66.5 9.5 1.5e-18 66.5 9.5 4.0 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAX73144.1 - 0.04 14.1 0.3 64 3.7 0.0 4.1 2 2 4 6 6 6 0 Centrosomal spindle body, CEP44 PTS_EIIA_1 PF00358.20 EAX73144.1 - 0.072 12.8 0.1 0.85 9.4 0.0 2.5 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 TFIIA PF03153.13 EAX73146.1 - 0.15 12.0 9.3 0.18 11.8 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EAX73146.1 - 3.3 6.3 7.1 3.8 6.1 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VirE PF05272.11 EAX73147.1 - 0.039 13.7 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Pox_A32 PF04665.12 EAX73147.1 - 0.048 13.1 0.3 0.12 11.8 0.1 1.6 1 1 1 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 EAX73147.1 - 0.092 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EAX73147.1 - 0.14 11.0 0.1 5.5 5.8 0.1 2.0 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 EAX73147.1 - 0.25 10.7 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arm-DNA-bind_5 PF17293.2 EAX73148.1 - 4.1 7.9 14.3 1.4 9.4 7.5 3.2 2 2 0 2 2 2 0 Arm DNA-binding domain DUF4107 PF13389.6 EAX73149.1 - 0.065 13.4 0.3 0.1 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX73150.1 - 2e-07 30.7 2.6 2.8e-07 30.2 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73150.1 - 0.0039 16.9 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF2805 PF10985.8 EAX73150.1 - 0.033 14.6 2.5 0.55 10.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) IstB_IS21 PF01695.17 EAX73150.1 - 0.059 13.1 0.1 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73150.1 - 0.2 11.6 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73150.1 - 0.45 10.7 8.5 5.3 7.3 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) FAS_N PF17828.1 EAX73152.1 - 0.019 15.0 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73153.1 - 0.017 15.5 0.4 0.024 15.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX73153.1 - 3.6 8.3 6.7 8.4 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF3839 PF12943.7 EAX73154.1 - 1.1e-07 31.5 1.6 1.7e-07 30.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX73155.1 - 1.1e-25 89.4 10.0 1.1e-25 89.4 10.0 3.9 2 1 2 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX73155.1 - 0.02 14.6 1.1 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX73156.1 - 1.4e-07 31.2 0.7 1.1e-06 28.3 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX73156.1 - 0.04 13.6 0.1 0.74 9.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX73156.1 - 0.098 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF257 PF03192.13 EAX73157.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX73157.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PTR PF12789.7 EAX73158.1 - 4.8e-46 154.7 33.4 5e-23 80.9 7.1 3.9 3 1 1 4 4 4 3 Phage tail repeat like DUF4795 PF16043.5 EAX73158.1 - 0.0011 18.7 8.4 0.0035 17.0 4.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX73158.1 - 0.7 10.3 3.9 37 4.7 0.1 3.8 2 2 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain NRDE-2 PF08424.10 EAX73159.1 - 0.041 13.0 0.3 0.045 12.9 0.3 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF3574 PF12098.8 EAX73161.1 - 0.13 12.1 0.4 0.27 11.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3574) ATP-synt_DE PF00401.20 EAX73161.1 - 1.2 9.5 4.8 11 6.3 0.3 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CTD PF12815.7 EAX73162.1 - 3.7e-05 24.2 13.7 0.089 13.4 9.5 4.0 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Nmad5 PF18757.1 EAX73162.1 - 0.0048 17.1 0.7 6.8 6.8 0.0 3.0 1 1 2 3 3 3 2 Nucleotide modification associated domain 5 Keratin_B2_2 PF13885.6 EAX73162.1 - 0.0061 16.5 32.9 1.4 8.9 14.0 2.8 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein Dicistro_VP4 PF11492.8 EAX73162.1 - 1.2 9.1 2.9 31 4.6 0.0 3.1 2 1 1 3 3 3 0 Cricket paralysis virus, VP4 JMY PF15871.5 EAX73163.1 - 0.033 13.5 0.3 0.051 12.9 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX73163.1 - 0.28 11.2 4.0 0.8 9.8 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5065) Pox_D5 PF03288.16 EAX73164.1 - 6.7e-06 26.5 2.7 3.7e-05 24.1 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73164.1 - 0.023 15.3 0.1 0.043 14.4 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73164.1 - 0.063 13.3 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73165.1 - 2.2e-59 199.5 9.1 2.4e-59 199.3 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX73166.1 - 0.68 9.9 2.7 1.7 8.6 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4106 PF13388.6 EAX73167.1 - 3e-216 718.5 56.2 6.3e-126 421.0 18.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) SPX PF03105.19 EAX73167.1 - 0.096 12.6 6.4 0.16 11.8 6.4 1.4 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 EAX73167.1 - 3.5 6.2 15.8 5.9 5.5 15.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EAX73167.1 - 9.2 6.1 34.1 0.33 10.9 25.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMP PF05017.14 EAX73170.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Myc_N PF01056.18 EAX73171.1 - 0.09 12.7 1.1 0.1 12.5 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EAX73171.1 - 0.39 10.0 2.6 0.51 9.6 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAX73171.1 - 1.1 9.7 14.5 7.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain T5orf172 PF10544.9 EAX73172.1 - 4.5e-07 30.4 0.1 7.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 T5orf172 domain PSP PF04046.16 EAX73173.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73174.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX73175.1 - 0.057 13.9 0.2 0.098 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX73176.1 - 3.5e-42 142.8 0.6 8e-42 141.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX73177.1 - 3.2e-07 30.8 0.4 6.4e-07 29.9 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain TFIIA PF03153.13 EAX73178.1 - 8.4 6.3 16.8 9.4 6.1 16.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T5orf172 PF10544.9 EAX73180.1 - 9.7e-07 29.3 0.3 1.8e-06 28.4 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73181.1 - 3e-35 120.5 0.3 9.4e-35 118.8 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX73182.1 - 8e-07 28.8 2.4 1e-06 28.4 2.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX73182.1 - 0.022 14.5 0.3 0.094 12.4 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX73182.1 - 0.036 13.6 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Zot PF05707.12 EAX73182.1 - 0.05 13.2 0.2 0.065 12.9 0.2 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX73182.1 - 0.086 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73182.1 - 0.23 11.5 1.9 2.1 8.4 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73182.1 - 0.49 10.6 8.0 6.8 6.9 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX73184.1 - 5.1e-08 32.7 0.2 5.1e-08 32.7 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73184.1 - 0.0027 18.3 0.0 0.0062 17.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family MG2 PF01835.19 EAX73185.1 - 4.3e-05 23.9 1.1 0.0044 17.5 0.1 2.6 2 1 0 2 2 2 1 MG2 domain DUF4625 PF15418.6 EAX73185.1 - 4.7e-05 23.6 2.5 0.016 15.4 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) DapB_N PF01113.20 EAX73185.1 - 0.009 16.1 2.0 0.022 14.9 2.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ChitinaseA_N PF08329.10 EAX73185.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Chitinase A, N-terminal domain RIFIN PF02009.16 EAX73185.1 - 0.015 15.2 6.9 0.018 15.0 6.9 1.2 1 0 0 1 1 1 0 Rifin DUF2914 PF11141.8 EAX73185.1 - 0.03 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) NPCBM_assoc PF10633.9 EAX73185.1 - 0.037 14.3 7.5 0.042 14.1 0.2 3.3 3 2 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PKD PF00801.20 EAX73185.1 - 0.048 13.5 0.2 0.42 10.5 0.0 2.5 2 1 0 2 2 2 0 PKD domain bMG6 PF17962.1 EAX73185.1 - 0.099 12.8 1.1 2.5 8.3 0.1 2.5 2 1 0 2 2 2 0 Bacterial macroglobulin domain 6 Amnionless PF14828.6 EAX73185.1 - 0.14 11.0 0.4 0.2 10.5 0.4 1.3 1 0 0 1 1 1 0 Amnionless He_PIG PF05345.12 EAX73185.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.0 2 1 1 3 3 3 0 Putative Ig domain EMP24_GP25L PF01105.24 EAX73185.1 - 0.26 11.2 5.2 1.8 8.5 5.2 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4328 PF14219.6 EAX73185.1 - 0.39 10.3 4.7 0.16 11.5 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Ank_5 PF13857.6 EAX73186.1 - 4.7e-36 122.4 9.6 3e-11 43.3 0.2 3.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX73186.1 - 7.9e-35 118.8 6.3 3.2e-10 40.3 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX73186.1 - 1.8e-34 118.2 12.4 2.3e-17 63.3 0.9 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX73186.1 - 1.2e-29 101.4 6.7 4.1e-08 33.3 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX73186.1 - 2e-28 95.3 5.8 8.1e-07 28.9 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat MetallophosN PF16371.5 EAX73186.1 - 8.7e-06 25.9 0.0 16 5.8 0.0 4.0 1 1 3 4 4 4 0 N terminal of Calcineurin-like phosphoesterase Arg_repressor PF01316.21 EAX73186.1 - 0.001 18.7 0.1 30 4.4 0.0 4.0 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Stap_Strp_toxin PF01123.20 EAX73186.1 - 0.01 16.6 4.0 3.5 8.6 0.1 3.5 1 1 3 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain Glyco_hydro_20b PF02838.15 EAX73186.1 - 0.012 16.3 0.4 3.4 8.5 0.2 3.0 1 1 2 3 3 3 0 Glycosyl hydrolase family 20, domain 2 Phage_GPA PF05840.13 EAX73186.1 - 0.02 14.0 0.0 7.9 5.5 0.0 2.7 1 1 1 2 2 2 0 Bacteriophage replication gene A protein (GPA) DUF348 PF03990.14 EAX73186.1 - 0.037 13.8 0.5 74 3.2 0.0 4.0 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain DUF3718 PF12514.8 EAX73186.1 - 0.048 13.8 2.3 8.9 6.5 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3718) Chal_sti_synt_N PF00195.19 EAX73187.1 - 0.066 12.6 0.2 0.12 11.7 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX73187.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX73188.1 - 2.2e-156 518.5 13.2 2.5e-156 518.3 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73188.1 - 0.1 12.4 0.7 0.35 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX73188.1 - 0.6 10.6 4.0 3.8 8.0 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73191.1 - 9.7e-117 388.7 11.1 1.2e-116 388.3 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73191.1 - 0.0083 16.6 1.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX73191.1 - 0.081 13.5 0.6 0.21 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX73192.1 - 0.044 14.2 0.5 0.096 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX73193.1 - 5.5e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX73193.1 - 0.034 14.3 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers PRD PF00874.20 EAX73193.1 - 0.042 14.2 0.8 0.097 13.0 0.1 1.9 2 0 0 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX73194.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX73194.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX73194.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX73194.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX73194.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX73195.1 - 4.3e-25 88.6 5.0 6.2e-25 88.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX73196.1 - 1.3e-42 144.2 0.9 3.3e-42 142.9 0.3 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX73196.1 - 0.038 14.2 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) TMP PF05017.14 EAX73197.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73198.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX73199.1 - 1.1e-09 38.2 7.9 7.2e-09 35.6 1.5 5.4 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX73199.1 - 0.024 14.2 13.6 0.12 11.9 1.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF5017 PF16409.5 EAX73199.1 - 0.14 11.6 1.9 2.1 7.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) DUF4108 PF13390.6 EAX73200.1 - 1.7e-51 173.9 5.2 1.8e-51 173.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX73201.1 - 2e-25 89.6 7.0 1.3e-24 86.9 7.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73201.1 - 0.15 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) KilA-N PF04383.13 EAX73202.1 - 3.6e-23 81.6 0.3 5.5e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX73202.1 - 0.036 14.0 0.0 0.088 12.8 0.0 1.6 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3074 PF11274.8 EAX73202.1 - 0.042 13.8 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) KilA-N PF04383.13 EAX73203.1 - 3.6e-20 71.9 0.2 4.5e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX73206.1 - 2.6e-50 168.3 29.4 8.6e-34 115.4 15.4 4.0 2 2 2 4 4 3 2 Phage tail repeat like DUF5365 PF17326.2 EAX73207.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX73207.1 - 0.027 14.8 0.3 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 PWI domain PTR PF12789.7 EAX73208.1 - 1.1e-09 38.1 10.9 2.5e-09 37.1 3.9 5.7 5 1 0 5 5 5 2 Phage tail repeat like DUF1493 PF07377.12 EAX73209.1 - 0.03 14.8 0.4 0.075 13.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73209.1 - 0.12 12.5 1.3 6 7.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX73211.1 - 6.3e-140 464.6 11.6 7.1e-140 464.4 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX73211.1 - 0.0034 17.6 0.4 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF29 KELK PF15796.5 EAX73211.1 - 0.35 11.4 3.5 1.3 9.6 1.1 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73212.1 - 1.3e-86 290.0 6.2 1.5e-86 289.8 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Phage_fiber PF03335.13 EAX73213.1 - 0.039 14.1 12.8 2.5 8.5 0.3 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat YmaF PF12788.7 EAX73213.1 - 0.072 13.6 5.7 20 5.8 0.1 3.0 2 1 0 2 2 2 0 YmaF family PTR PF12789.7 EAX73213.1 - 0.11 12.5 9.0 0.25 11.4 2.1 3.0 3 1 0 3 3 3 0 Phage tail repeat like Mito_fiss_reg PF05308.11 EAX73214.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73214.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX73215.1 - 6.3e-43 145.2 0.2 2e-42 143.6 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX73216.1 - 4.1e-07 30.5 0.2 8.1e-07 29.5 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX73217.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73218.1 - 0.029 14.8 0.3 0.041 14.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73218.1 - 2.8 8.0 5.3 2.9 7.9 5.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX73219.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX73219.1 - 0.11 12.5 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX73220.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73220.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4795 PF16043.5 EAX73221.1 - 0.0056 16.3 9.3 0.081 12.5 1.3 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4795) PTR PF12789.7 EAX73221.1 - 6.3 6.9 20.2 0.17 12.0 2.6 5.3 5 2 1 6 6 6 0 Phage tail repeat like Phage-A118_gp45 PF10653.9 EAX73223.1 - 0.19 11.8 0.0 26 4.9 0.0 2.1 1 1 1 2 2 2 0 Protein gp45 of Bacteriophage A118 DNA_pol_B_2 PF03175.13 EAX73224.1 - 1.5e-11 43.9 0.3 3.3e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX73224.1 - 0.039 13.3 0.4 0.06 12.7 0.4 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF2939 PF11159.8 EAX73225.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73225.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX73226.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase GGDEF PF00990.21 EAX73227.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX73227.1 - 0.12 12.7 10.1 0.17 12.2 10.1 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX73227.1 - 7.7 6.5 6.5 17 5.4 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73228.1 - 3e-60 202.3 5.7 3.3e-60 202.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) IBN_N PF03810.19 EAX73229.1 - 1.9e-07 30.9 0.1 4.4e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ly49 PF08391.10 EAX73230.1 - 0.28 11.6 1.6 0.34 11.3 1.6 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX73230.1 - 0.44 10.5 2.7 0.82 9.6 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73231.1 - 3.4e-61 205.3 7.0 3.8e-61 205.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73231.1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein GPS2_interact PF15784.5 EAX73233.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73233.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Gly-zipper_Omp PF13488.6 EAX73234.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX73234.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX73234.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX73235.1 - 2.2e-17 62.8 7.7 5e-17 61.7 1.4 2.9 3 0 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX73235.1 - 1.4 9.5 11.5 16 6.1 0.1 3.5 2 2 0 2 2 2 0 YmaF family DUF3213 PF11491.8 EAX73236.1 - 0.042 14.0 0.3 0.098 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX73238.1 - 2.1e-07 31.4 0.3 3.9e-07 30.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MCPVI PF02993.14 EAX73239.1 - 2.4 7.9 7.6 15 5.4 0.1 2.1 1 1 0 2 2 2 0 Minor capsid protein VI GCD14 PF08704.10 EAX73239.1 - 9.6 5.8 7.4 1.5 8.4 2.3 1.8 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Trypan_PARP PF05887.11 EAX73240.1 - 0.058 13.4 5.0 0.057 13.4 5.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GGDEF PF00990.21 EAX73240.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX73241.1 - 3.2e-61 205.5 8.3 3.5e-61 205.3 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73242.1 - 4.9e-05 23.7 2.9 0.00028 21.3 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73242.1 - 0.077 13.6 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73242.1 - 0.085 12.8 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PapD_N PF00345.20 EAX73244.1 - 0.027 14.4 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1031 PF06275.11 EAX73245.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX73245.1 - 0.058 13.5 0.4 0.28 11.3 0.3 1.9 1 1 1 2 2 2 0 Annexin HARE-HTH PF05066.13 EAX73245.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Trypan_PARP PF05887.11 EAX73246.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX73247.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Amidase02_C PF12123.8 EAX73248.1 - 0.008 15.8 0.1 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX73250.1 - 1.8e-10 40.7 22.3 8.2e-09 35.4 5.6 4.1 4 0 0 4 4 4 2 Phage tail repeat like HD_2 PF12917.7 EAX73250.1 - 0.039 13.7 0.3 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme Ribosomal_S4e PF00900.20 EAX73250.1 - 0.12 12.4 0.5 15 5.6 0.0 2.7 3 0 0 3 3 3 0 Ribosomal family S4e IL2 PF00715.17 EAX73250.1 - 0.14 12.1 2.8 9.7 6.1 0.1 2.5 3 0 0 3 3 3 0 Interleukin 2 Pox_D5 PF03288.16 EAX73252.1 - 0.00014 22.3 2.4 0.00089 19.7 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX73253.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX73254.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein KilA-N PF04383.13 EAX73257.1 - 4.6e-38 129.5 0.3 1.1e-37 128.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73257.1 - 0.0042 17.7 0.2 0.014 16.0 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family DUF3839 PF12943.7 EAX73258.1 - 1e-157 522.8 13.3 1.1e-157 522.7 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73258.1 - 0.12 12.3 0.7 0.43 10.4 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX73258.1 - 0.17 12.3 6.1 1.4 9.4 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX73259.1 - 4e-07 30.5 0.3 8e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73260.1 - 2.7e-42 143.1 1.4 3.1e-42 142.9 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73260.1 - 0.0063 17.1 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Parathyroid hormone family DUF3839 PF12943.7 EAX73262.1 - 3.8e-78 262.3 9.5 5.1e-78 261.9 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX73262.1 - 0.11 13.5 0.7 0.25 12.3 0.6 1.7 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF3781 PF12636.7 EAX73264.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX73265.1 - 2.3e-65 219.7 6.4 3.6e-65 219.0 6.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2960 PF11173.8 EAX73266.1 - 0.022 15.2 0.2 0.046 14.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX73266.1 - 0.042 13.9 1.6 0.16 12.0 0.5 2.2 2 1 1 3 3 3 0 YpjP-like protein MATalpha_HMGbox PF04769.12 EAX73267.1 - 0.081 12.2 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box DUF3877 PF12993.7 EAX73267.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) RIH_assoc PF08454.11 EAX73268.1 - 0.046 13.6 0.3 0.15 11.9 0.3 1.9 1 1 1 2 2 2 0 RyR and IP3R Homology associated DUF2939 PF11159.8 EAX73271.1 - 0.022 15.1 0.3 0.027 14.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX73272.1 - 0.006 16.6 0.3 0.008 16.2 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX73273.1 - 3.1e-30 104.3 0.3 1e-29 102.6 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX73273.1 - 0.032 14.4 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) PapD_N PF00345.20 EAX73274.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX73274.1 - 0.05 13.6 0.2 0.05 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX73277.1 - 5e-40 137.5 5.0 7.2e-40 137.0 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX73277.1 - 0.073 13.2 0.2 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers ZapB PF06005.12 EAX73277.1 - 0.14 12.6 1.0 0.76 10.3 0.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX73277.1 - 0.37 11.2 2.9 0.96 9.8 1.1 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain BRE1 PF08647.11 EAX73277.1 - 0.87 9.7 5.4 3.9 7.6 1.5 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4108 PF13390.6 EAX73279.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Glyco_hydro_30 PF02055.16 EAX73280.1 - 8.9e-37 126.9 2.5 1.1e-36 126.5 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX73280.1 - 3.6e-08 33.0 0.9 5.4e-08 32.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EAX73280.1 - 2.1e-07 31.0 2.1 4.2e-07 30.1 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF4106 PF13388.6 EAX73281.1 - 1.1e-208 693.6 21.6 1.3e-208 693.3 21.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.10 EAX73281.1 - 5.3 5.6 7.6 9.1 4.8 7.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypan_PARP PF05887.11 EAX73282.1 - 0.012 15.6 5.3 0.018 15.0 5.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX73283.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73283.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliD_N PF02465.18 EAX73285.1 - 0.19 12.5 4.8 0.26 12.0 4.8 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX73285.1 - 1 8.0 3.9 1.3 7.8 3.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HC2 PF07382.11 EAX73286.1 - 3.2e-08 33.9 11.0 3.5e-08 33.8 11.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX73286.1 - 8.9e-05 22.6 1.6 0.00011 22.2 1.6 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) XAP5 PF04921.14 EAX73286.1 - 0.42 10.4 4.7 0.57 10.0 4.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Aurora-A_bind PF09041.10 EAX73286.1 - 2 8.6 8.5 3.2e+02 1.5 8.5 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX73286.1 - 3 7.9 5.1 1e+02 3.0 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) YvrJ PF12841.7 EAX73287.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Pox_D5 PF03288.16 EAX73288.1 - 4.7e-05 23.8 2.7 0.00026 21.4 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX73289.1 - 1e-64 216.8 6.2 1.1e-64 216.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FliJ PF02050.16 EAX73292.1 - 0.0082 16.4 0.1 0.01 16.1 0.1 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DUF4108 PF13390.6 EAX73293.1 - 2.8e-42 144.0 3.6 3.2e-42 143.9 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73293.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX73295.1 - 4.5e-05 23.5 0.1 5.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX73295.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX73295.1 - 0.002 18.4 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX73295.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX73295.1 - 0.0036 17.6 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73295.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX73295.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX73295.1 - 0.086 12.5 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX73295.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX73296.1 - 2.6e-133 442.9 13.3 7.7e-133 441.4 13.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX73296.1 - 0.054 13.9 2.2 0.089 13.2 0.3 1.9 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX73296.1 - 0.066 13.6 1.1 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX73296.1 - 0.29 11.7 3.7 0.26 11.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX73296.1 - 1.5 9.3 8.7 5.1 7.6 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73298.1 - 3.7e-125 416.2 7.3 4.2e-125 416.1 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73298.1 - 0.073 13.5 3.0 2.3 8.7 1.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Z1 PF10593.9 EAX73298.1 - 0.073 12.6 0.6 0.11 11.9 0.4 1.4 1 1 0 1 1 1 0 Z1 domain Pox_A32 PF04665.12 EAX73299.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73299.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73299.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73299.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73299.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73299.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73299.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX73300.1 - 1.2e-96 322.9 7.6 1.4e-96 322.7 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX73300.1 - 0.11 13.5 0.6 3.3 8.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) KilA-N PF04383.13 EAX73301.1 - 1.6e-25 89.1 1.4 2.2e-25 88.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX73301.1 - 0.0032 17.6 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX73303.1 - 6.5e-76 255.0 9.9 8.6e-76 254.6 9.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX73303.1 - 0.063 14.2 0.2 0.12 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KilA-N PF04383.13 EAX73304.1 - 5.6e-31 106.7 0.4 1.6e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF1493 PF07377.12 EAX73306.1 - 0.028 14.9 0.9 0.055 13.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX73307.1 - 1.8e-45 153.4 0.1 1.8e-45 153.4 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX73307.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) PTR PF12789.7 EAX73308.1 - 2.7e-24 85.0 21.8 2e-16 59.8 3.1 4.4 3 1 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX73308.1 - 0.016 15.0 0.1 0.047 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) CppA_C PF14507.6 EAX73308.1 - 2.9 8.7 6.9 0.94 10.2 0.3 2.9 4 0 0 4 4 4 0 CppA C-terminal DUF3781 PF12636.7 EAX73312.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX73313.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73313.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX73314.1 - 3.8e-31 107.2 0.4 8.2e-31 106.2 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX73316.1 - 7.5e-44 149.7 1.0 8.3e-44 149.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73316.1 - 0.089 13.2 0.6 0.11 12.8 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX73317.1 - 0.0073 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX73319.1 - 5.1e-73 244.6 3.7 6.7e-73 244.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX73320.1 - 4.3e-43 146.7 2.9 4.7e-43 146.5 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73320.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PTR PF12789.7 EAX73322.1 - 1.2e-24 86.1 13.2 1.2e-24 86.1 13.2 3.4 3 1 1 4 4 3 1 Phage tail repeat like Mito_fiss_reg PF05308.11 EAX73323.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73323.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PapD_N PF00345.20 EAX73325.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73325.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family rve PF00665.26 EAX73327.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX73327.1 - 0.00059 20.1 0.1 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 DDE domain Meiosis_expr PF15163.6 EAX73330.1 - 0.042 14.5 0.4 0.063 14.0 0.4 1.3 1 0 0 1 1 1 0 Meiosis-expressed Tho2 PF11262.8 EAX73330.1 - 0.076 12.2 2.5 0.088 12.0 2.5 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX73330.1 - 0.39 10.7 7.4 0.091 12.7 2.9 2.4 3 1 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX73332.1 - 1.4e-24 86.9 5.0 2.2e-24 86.3 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX73332.1 - 0.02 15.0 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers ZapB PF06005.12 EAX73332.1 - 0.067 13.7 0.7 0.44 11.0 0.1 2.0 1 1 0 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX73333.1 - 5.7e-16 58.4 0.4 1.7e-15 56.8 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73333.1 - 0.069 13.8 0.0 0.16 12.6 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX73335.1 - 6.7e-07 29.8 0.4 1.3e-06 28.9 0.4 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73336.1 - 3e-42 143.0 0.2 7.7e-42 141.7 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73336.1 - 0.036 14.7 0.0 0.095 13.3 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family KilA-N PF04383.13 EAX73340.1 - 1.9e-11 43.8 0.1 3.8e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain NTS PF15447.6 EAX73340.1 - 0.083 13.4 2.4 2.5 8.7 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX73341.1 - 1.8e-71 240.4 4.7 2.3e-71 240.1 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73341.1 - 0.089 13.4 0.2 0.13 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Aminotran_1_2 PF00155.21 EAX73341.1 - 0.1 11.7 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4108 PF13390.6 EAX73342.1 - 1e-52 177.9 5.6 1.1e-52 177.7 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73343.1 - 4.3e-05 23.9 2.1 0.00025 21.4 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like VirE PF05272.11 EAX73343.1 - 5.2e-05 23.1 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX73343.1 - 0.0095 15.0 0.9 0.014 14.5 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX73343.1 - 0.074 13.4 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 RNA helicase DUF3198 PF11433.8 EAX73343.1 - 0.13 12.1 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) WW_FCH_linker PF16623.5 EAX73344.1 - 0.00058 20.6 36.8 6.4 7.6 1.1 8.4 1 1 7 8 8 8 3 Unstructured linker region between on GAS7 protein LDB19 PF13002.7 EAX73344.1 - 0.0099 15.6 3.8 14 5.3 0.1 4.0 1 1 1 3 3 3 2 Arrestin_N terminal like KAAG1 PF15354.6 EAX73344.1 - 0.13 12.9 20.8 10 6.7 0.6 4.8 1 1 4 5 5 5 0 Kidney-associated antigen 1 PK_C PF02887.16 EAX73344.1 - 0.13 12.4 10.3 7e+02 0.5 10.3 3.7 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain ApoM PF11032.8 EAX73344.1 - 1.4 8.6 7.9 16 5.1 0.6 3.4 1 1 4 5 5 5 0 ApoM domain BORG_CEP PF14957.6 EAX73344.1 - 3.3 8.9 31.2 57 4.9 10.3 5.6 2 1 2 4 4 4 0 Cdc42 effector DDE_1 PF03184.19 EAX73345.1 - 1.2e-12 47.8 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidase02_C PF12123.8 EAX73346.1 - 0.051 13.3 0.5 0.23 11.2 0.0 2.3 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX73347.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX73347.1 - 0.046 13.7 0.6 0.062 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX73348.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73348.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX73349.1 - 0.033 14.3 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX73349.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX73349.1 - 0.098 12.6 2.7 0.098 12.6 2.7 2.1 2 1 0 2 2 2 0 Spo12 family FAS_N PF17828.1 EAX73350.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73351.1 - 0.012 16.0 0.6 0.015 15.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73351.1 - 1.4 7.9 4.0 1.4 7.9 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX73351.1 - 4.3 8.0 6.6 9.2 7.0 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX73351.1 - 6.7 6.7 7.9 7.4 6.6 7.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX73353.1 - 1.6e-86 289.8 7.7 1.8e-86 289.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73353.1 - 0.042 13.3 0.4 0.047 13.2 0.4 1.1 1 0 0 1 1 1 0 Z1 domain DUF4841 PF16129.5 EAX73354.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) PapD_N PF00345.20 EAX73355.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73355.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mito_fiss_reg PF05308.11 EAX73356.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73356.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GPS2_interact PF15784.5 EAX73358.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73358.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX73359.1 - 8.6e-23 80.9 4.3 1.2e-22 80.5 4.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX73360.1 - 5.7e-14 51.9 10.5 5.2e-10 39.2 0.3 4.6 4 0 0 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX73360.1 - 0.032 14.8 9.9 0.79 10.3 0.3 3.8 3 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX73360.1 - 0.49 10.0 10.7 35 3.9 10.7 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX73361.1 - 0.02 15.3 0.5 0.05 14.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX73362.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat LRR_5 PF13306.6 EAX73363.1 - 1.1e-07 31.9 15.0 0.002 18.1 0.6 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Peptidase_M8 PF01457.16 EAX73365.1 - 6.7e-26 91.1 0.0 1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Pox_D5 PF03288.16 EAX73366.1 - 3.5e-05 24.2 2.1 0.0002 21.8 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73366.1 - 0.022 15.4 0.1 0.043 14.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73366.1 - 0.059 13.4 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73367.1 - 2.5e-57 192.8 9.0 2.8e-57 192.7 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX73368.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX73368.1 - 0.57 10.1 2.2 1.2 9.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX73369.1 - 5.5e-05 23.2 2.4 0.00011 22.2 2.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73369.1 - 0.00035 20.4 0.0 0.00053 19.8 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73369.1 - 0.0004 20.7 0.0 0.00064 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73369.1 - 0.00096 19.0 0.7 0.0024 17.7 0.7 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73369.1 - 0.0087 16.4 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73369.1 - 0.044 13.2 0.1 0.063 12.7 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX73369.1 - 0.057 13.2 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX73369.1 - 0.062 13.0 0.4 0.11 12.2 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX73369.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX73369.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX73369.1 - 0.23 11.7 5.3 4.9 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DDR PF08841.10 EAX73372.1 - 0.074 12.0 0.1 0.076 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX73373.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX73374.1 - 6.3e-07 29.1 2.5 6.3e-07 29.1 2.5 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX73374.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX73374.1 - 4.8e-05 23.2 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX73374.1 - 0.00016 21.8 3.5 0.00036 20.6 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73374.1 - 0.00057 19.7 0.1 0.0011 18.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73374.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX73374.1 - 0.0019 17.8 0.4 0.013 15.2 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX73374.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX73374.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX73374.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX73374.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX73374.1 - 0.58 10.4 4.1 14 6.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX73376.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX73377.1 - 0.014 15.8 0.7 0.025 15.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX73378.1 - 3e-22 78.6 0.1 3.7e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain DUF4378 PF14309.6 EAX73379.1 - 0.006 17.0 0.0 0.006 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) Pox_A32 PF04665.12 EAX73380.1 - 8.8e-05 22.1 3.5 0.00016 21.2 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX73380.1 - 0.0061 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX73380.1 - 0.0099 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX73380.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Pox_A32 PF04665.12 EAX73384.1 - 1.5e-07 31.2 0.3 1.6e-07 31.0 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX73384.1 - 0.0047 15.8 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX73384.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX73384.1 - 0.044 13.7 0.4 0.43 10.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX73384.1 - 0.093 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX73385.1 - 3.7e-73 245.9 6.7 4.9e-73 245.5 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX73385.1 - 0.13 11.8 0.3 0.37 10.3 0.0 1.9 2 1 0 2 2 2 0 SLOG cluster2 DUF1043 PF06295.12 EAX73386.1 - 0.031 14.3 0.4 0.053 13.5 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX73387.1 - 0.0094 16.3 0.4 0.011 16.2 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73387.1 - 2.5 8.1 4.9 2.7 8.0 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX73388.1 - 0.01 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4106 PF13388.6 EAX73389.1 - 5.2e-212 704.5 24.6 6.1e-212 704.3 24.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Endostatin PF06482.11 EAX73389.1 - 0.95 8.9 5.9 1.5 8.2 5.9 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ndc1_Nup PF09531.10 EAX73389.1 - 4.3 5.9 11.0 6.9 5.2 11.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_B_2 PF03175.13 EAX73390.1 - 4.9e-24 85.0 7.9 2.3e-23 82.8 7.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73390.1 - 0.11 12.5 0.1 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX73390.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_A32 PF04665.12 EAX73391.1 - 0.00013 21.6 4.9 0.00023 20.7 4.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX73391.1 - 0.0032 17.5 0.7 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX73391.1 - 0.057 13.7 1.4 0.15 12.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX73392.1 - 0.018 14.3 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Y_phosphatase2 PF03162.13 EAX73392.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Pox_A32 PF04665.12 EAX73393.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73393.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73393.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73393.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) TMP PF05017.14 EAX73395.1 - 0.032 14.7 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73396.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX73397.1 - 0.071 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Mito_fiss_reg PF05308.11 EAX73399.1 - 0.058 13.5 1.2 0.063 13.3 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73399.1 - 0.63 9.5 5.8 0.66 9.4 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX73401.1 - 0.052 14.0 0.4 0.094 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73401.1 - 0.27 11.3 3.4 9.3 6.4 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PapD_N PF00345.20 EAX73403.1 - 0.053 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73403.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Trypan_PARP PF05887.11 EAX73404.1 - 0.031 14.2 10.1 0.037 14.0 10.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_22 PF13401.6 EAX73405.1 - 2.7e-05 24.4 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX73405.1 - 5.1e-05 23.1 0.3 0.3 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX73405.1 - 0.00032 20.8 3.8 0.00054 20.0 3.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX73405.1 - 0.00034 20.2 2.1 0.00034 20.2 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX73405.1 - 0.0011 18.9 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX73405.1 - 0.0011 18.8 0.1 0.002 17.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX73405.1 - 0.0014 18.3 0.4 0.01 15.5 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX73405.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX73405.1 - 0.051 13.1 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX73405.1 - 0.058 12.8 0.0 0.097 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Elong_Iki1 PF10483.9 EAX73405.1 - 0.059 12.9 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX73405.1 - 0.075 13.5 0.1 0.68 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX73405.1 - 0.2 12.0 3.9 6.1 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX73405.1 - 1.6 9.2 5.6 0.34 11.3 0.7 2.3 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 DUF2666 PF10869.8 EAX73405.1 - 6.4 7.0 13.6 5 7.3 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF3781 PF12636.7 EAX73407.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX73408.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX73408.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX73409.1 - 0.11 12.4 9.8 0.13 12.3 9.8 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX73409.1 - 3.9 7.9 6.4 4.4 7.7 6.4 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR PF12789.7 EAX73410.1 - 1.1e-34 118.3 22.0 3.9e-31 106.9 14.0 3.8 3 1 1 4 4 4 2 Phage tail repeat like DNA_pol_B_2 PF03175.13 EAX73411.1 - 1.4e-11 44.0 2.1 1e-10 41.1 2.1 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73411.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4108 PF13390.6 EAX73412.1 - 1.2e-59 200.3 5.5 1.3e-59 200.2 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX73414.1 - 2.3e-05 24.5 0.1 3.1e-05 24.0 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73414.1 - 0.00032 20.5 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73414.1 - 0.0015 18.8 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73414.1 - 0.0015 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73414.1 - 0.0055 17.1 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73414.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX73414.1 - 0.069 12.9 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX73414.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX73414.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX73414.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4106 PF13388.6 EAX73415.1 - 1.1e-94 318.1 4.0 1.7e-94 317.5 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) TrfA PF07042.11 EAX73415.1 - 0.12 11.4 0.3 5.1 6.1 0.0 2.1 2 0 0 2 2 2 0 TrfA protein VirE PF05272.11 EAX73416.1 - 1.1e-05 25.3 0.1 2.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX73416.1 - 8.2e-05 23.0 2.4 0.00052 20.5 2.4 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX73416.1 - 0.018 14.1 1.0 0.027 13.6 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX73416.1 - 0.047 14.1 0.5 0.16 12.4 0.1 2.1 1 1 0 2 2 2 0 RNA helicase SplA PF11132.8 EAX73416.1 - 0.08 12.7 0.3 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) DUF4108 PF13390.6 EAX73417.1 - 2.4e-61 205.8 8.5 2.7e-61 205.7 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73418.1 - 5.2e-05 23.6 2.2 0.00034 21.1 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX73418.1 - 0.033 13.3 1.1 0.047 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX73419.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX73419.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Phage_fiber PF03335.13 EAX73421.1 - 1.4 9.3 22.2 1.3 9.4 3.9 3.6 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX73422.1 - 2.6e-24 85.0 13.3 2.6e-24 85.0 13.3 3.0 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX73422.1 - 0.042 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX73422.1 - 0.068 13.7 16.1 1.6 9.3 6.6 3.3 2 2 0 2 2 2 0 YmaF family Pox_D5 PF03288.16 EAX73423.1 - 3.5e-05 24.2 2.1 0.0002 21.8 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73423.1 - 0.022 15.4 0.1 0.043 14.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73423.1 - 0.059 13.4 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73424.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KIAA1430 PF13879.6 EAX73426.1 - 0.016 16.0 2.5 0.024 15.4 2.5 1.3 1 0 0 1 1 1 0 KIAA1430 homologue GED PF02212.18 EAX73427.1 - 0.038 14.1 2.5 0.064 13.4 2.5 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain RskA PF10099.9 EAX73427.1 - 0.062 13.6 0.4 0.065 13.5 0.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 EAX73427.1 - 2.6 8.0 4.2 2.6 8.0 4.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HTH_32 PF13565.6 EAX73427.1 - 2.9 8.6 5.2 13 6.5 5.2 1.9 1 1 0 1 1 1 0 Homeodomain-like domain DUF5365 PF17326.2 EAX73432.1 - 0.027 14.9 0.1 0.064 13.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX73432.1 - 0.037 14.3 0.4 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF3839 PF12943.7 EAX73433.1 - 6e-121 402.4 12.9 8e-121 402.0 12.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73433.1 - 0.23 12.0 4.9 1.2 9.6 0.0 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX73433.1 - 0.5 10.7 0.1 0.5 10.7 0.1 2.6 4 0 0 4 4 4 0 PRD domain PTR PF12789.7 EAX73436.1 - 8.5e-08 32.1 2.4 8.5e-08 32.1 2.4 4.3 5 0 0 5 5 5 2 Phage tail repeat like IL2 PF00715.17 EAX73436.1 - 0.2 11.6 2.8 17 5.4 0.1 2.8 2 1 1 3 3 3 0 Interleukin 2 NPV_P10 PF05531.12 EAX73436.1 - 5.7 7.5 6.8 41 4.7 3.3 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DNA_pol_B_2 PF03175.13 EAX73437.1 - 5e-23 81.7 4.2 6.3e-23 81.4 4.2 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73437.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4108 PF13390.6 EAX73438.1 - 3.9e-38 130.6 2.3 4.3e-38 130.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73438.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Amidase02_C PF12123.8 EAX73440.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase zinc-ribbons_6 PF07191.12 EAX73441.1 - 0.01 15.8 0.9 0.016 15.2 0.9 1.3 1 0 0 1 1 1 1 zinc-ribbons HNH_3 PF13392.6 EAX73444.1 - 4.2e-08 32.8 0.3 7.6e-08 32.0 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF2897 PF11446.8 EAX73447.1 - 0.016 15.0 3.6 0.022 14.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73448.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73449.1 - 9.8e-05 22.8 2.9 0.00057 20.3 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73449.1 - 0.071 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PSP PF04046.16 EAX73450.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73451.1 - 0.041 14.4 3.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat TPR_20 PF14561.6 EAX73452.1 - 0.021 15.2 0.7 0.41 11.0 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Alba PF01918.21 EAX73452.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.7 1 1 0 1 1 1 0 Alba PG_binding_2 PF08823.11 EAX73452.1 - 0.031 14.6 0.2 0.078 13.3 0.2 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain CSG2 PF16965.5 EAX73453.1 - 0.032 13.2 0.0 0.032 13.2 0.0 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator DUF3839 PF12943.7 EAX73454.1 - 1e-27 97.1 6.3 1.7e-27 96.5 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX73454.1 - 0.11 12.9 1.2 0.65 10.5 0.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB T5orf172 PF10544.9 EAX73455.1 - 6e-07 29.9 0.6 1.9e-06 28.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX73455.1 - 0.12 12.2 1.1 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX73455.1 - 0.16 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX73456.1 - 2.1e-15 56.8 3.6 3.5e-15 56.1 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX73456.1 - 0.046 14.2 0.7 0.26 11.8 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF3839 PF12943.7 EAX73457.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX73458.1 - 0.015 15.2 0.2 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 KilA-N domain T5orf172 PF10544.9 EAX73458.1 - 0.068 13.7 0.1 0.17 12.5 0.1 1.7 1 0 0 1 1 1 0 T5orf172 domain Lectin_legB PF00139.19 EAX73458.1 - 0.11 12.0 1.6 0.45 10.0 0.4 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX73459.1 - 2.8e-156 518.1 13.7 3.5e-156 517.8 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73459.1 - 0.14 12.0 1.4 0.37 10.7 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX73459.1 - 1.6 9.1 5.0 0.61 10.4 1.0 2.4 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF3839 PF12943.7 EAX73460.1 - 2.4e-128 426.7 5.2 2.7e-128 426.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX73461.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4106 PF13388.6 EAX73462.1 - 2.1e-157 524.7 32.7 9e-157 522.6 32.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3391 PF11871.8 EAX73462.1 - 2.5 8.6 18.3 5.6 7.5 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 EAX73462.1 - 3.8 7.4 26.8 1.4 8.8 14.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3781 PF12636.7 EAX73463.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX73464.1 - 1.9e-73 245.9 4.0 2.3e-73 245.7 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX73464.1 - 0.045 12.2 0.9 0.062 11.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4107 PF13389.6 EAX73467.1 - 5e-66 221.8 13.2 1.4e-64 217.1 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73467.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX73472.1 - 1.9e-154 512.1 12.6 2.4e-154 511.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX73472.1 - 0.0091 16.2 0.6 1.2 9.4 0.1 3.5 3 1 0 3 3 3 1 Rx N-terminal domain KELK PF15796.5 EAX73472.1 - 0.61 10.6 6.8 2 8.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX73472.1 - 2.1 8.7 6.6 5.4 7.4 0.2 3.7 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX73472.1 - 2.9 8.4 6.7 0.67 10.5 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX73474.1 - 1e-21 76.9 0.4 1.5e-21 76.3 0.4 1.3 1 0 0 1 1 1 1 KilA-N domain FAS_N PF17828.1 EAX73475.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73476.1 - 0.025 15.0 0.5 0.031 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73476.1 - 1.1 8.2 2.8 1.2 8.1 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX73476.1 - 1.5 8.8 5.6 1.6 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1493 PF07377.12 EAX73477.1 - 0.017 15.6 0.6 0.035 14.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Glyco_hydro_30 PF02055.16 EAX73480.1 - 2.9e-30 105.4 0.1 3.6e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX73480.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAX73480.1 - 0.002 17.8 0.1 0.095 12.3 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 DUF3839 PF12943.7 EAX73481.1 - 1.1e-06 28.3 1.5 1.9e-06 27.5 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Lectin_legB PF00139.19 EAX73482.1 - 0.0023 17.5 0.7 0.17 11.4 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX73482.1 - 0.0069 16.9 0.3 0.014 16.0 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73482.1 - 0.016 15.1 0.2 0.036 13.9 0.2 1.8 1 1 0 1 1 1 0 KilA-N domain DNA_pol_B_2 PF03175.13 EAX73483.1 - 8.9e-30 104.0 6.8 1.3e-29 103.4 6.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DDR PF08841.10 EAX73484.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX73485.1 - 0.043 13.8 8.6 0.061 13.3 8.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX73485.1 - 1.3 9.5 4.4 1.6 9.2 4.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4116 PF13475.6 EAX73486.1 - 0.029 14.1 0.1 0.11 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX73486.1 - 0.044 13.6 3.7 0.049 13.4 2.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) F420_ligase PF01996.16 EAX73486.1 - 0.067 12.5 0.5 0.1 12.0 0.5 1.3 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase DUF3417 PF11897.8 EAX73486.1 - 0.12 12.8 4.3 0.13 12.7 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) PTR PF12789.7 EAX73486.1 - 0.84 9.7 0.1 0.84 9.7 0.1 4.0 2 1 2 4 4 4 0 Phage tail repeat like Cgr1 PF03879.14 EAX73486.1 - 6.3 7.2 7.6 1.5 9.2 3.6 2.0 2 0 0 2 2 2 0 Cgr1 family KilA-N PF04383.13 EAX73487.1 - 7e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX73487.1 - 0.038 14.0 0.5 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX73487.1 - 0.29 10.5 0.7 1.4 8.3 0.3 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DNA_pol_B_2 PF03175.13 EAX73489.1 - 3.6e-29 102.0 6.3 6.3e-29 101.2 6.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX73489.1 - 0.023 14.0 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX73489.1 - 0.028 14.5 1.7 1.6 8.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4106 PF13388.6 EAX73491.1 - 1.7e-261 867.6 16.7 2.8e-261 866.9 16.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73491.1 - 0.016 15.5 0.1 0.62 10.4 0.2 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX73491.1 - 0.026 14.4 0.2 0.055 13.3 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) VirE PF05272.11 EAX73492.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX73492.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX73492.1 - 0.084 11.8 0.2 7.4 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF4249 PF14054.6 EAX73493.1 - 0.11 12.1 1.0 0.19 11.4 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4249) DUF1493 PF07377.12 EAX73496.1 - 0.015 15.7 0.5 0.03 14.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX73497.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73498.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP DUF2897 PF11446.8 EAX73499.1 - 0.32 10.9 3.2 0.65 9.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73500.1 - 9.6e-64 213.6 5.8 1.1e-63 213.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX73501.1 - 8.4e-07 28.8 0.1 1.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF1493 PF07377.12 EAX73502.1 - 0.025 15.0 0.6 0.057 13.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX73503.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX73503.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX73505.1 - 4.4e-48 162.8 6.0 4.9e-48 162.7 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GH97_C PF14509.6 EAX73505.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation GAGA_bind PF06217.12 EAX73506.1 - 0.082 13.2 4.5 0.1 12.9 4.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX73506.1 - 6.8 6.7 8.0 16 5.5 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX73508.1 - 1.5e-24 85.9 0.3 4.2e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73508.1 - 0.09 13.4 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX73508.1 - 0.094 13.4 1.3 13 6.6 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DNA_pol_B_2 PF03175.13 EAX73511.1 - 7.9e-25 87.6 11.7 3e-24 85.7 11.7 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX73512.1 - 2.7e-07 30.3 1.0 3.2e-07 30.1 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73512.1 - 0.0042 16.8 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73512.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73512.1 - 0.052 13.5 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX73513.1 - 0.055 13.3 3.0 0.11 12.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX73513.1 - 0.072 13.5 0.5 0.089 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX73514.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73515.1 - 1.9e-05 25.1 2.6 0.00014 22.3 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like PTR PF12789.7 EAX73516.1 - 6e-22 77.5 18.5 1.2e-16 60.5 1.6 4.8 6 0 0 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX73517.1 - 0.077 12.6 1.7 0.2 11.2 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX73517.1 - 0.34 11.0 12.4 0.13 12.3 2.6 3.9 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX73517.1 - 8.7 6.8 15.9 14 6.2 0.4 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX73518.1 - 6.7e-53 176.6 37.0 7.2e-35 118.9 16.2 5.0 4 2 2 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX73518.1 - 0.0032 17.1 11.3 0.088 12.4 6.0 3.2 2 2 0 2 2 2 2 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX73518.1 - 0.096 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) PTR PF12789.7 EAX73519.1 - 2.4e-23 81.9 8.7 2.4e-23 81.9 8.7 4.0 2 2 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX73519.1 - 0.025 14.3 1.4 0.051 13.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX73519.1 - 0.59 10.1 6.9 1.7 8.6 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF2939 PF11159.8 EAX73520.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73520.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX73520.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX73521.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX73521.1 - 0.082 12.9 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX73522.1 - 0.063 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain T5orf172 PF10544.9 EAX73526.1 - 1.8e-05 25.2 0.6 0.00032 21.2 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX73526.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX73526.1 - 0.027 14.0 0.6 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX73529.1 - 9e-127 421.5 6.2 1.1e-126 421.3 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73529.1 - 0.24 11.9 1.3 1.2 9.6 1.3 2.2 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX73530.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX73530.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Amidase02_C PF12123.8 EAX73531.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX73531.1 - 0.21 11.5 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) CG-1 PF03859.16 EAX73532.1 - 0.063 13.1 0.3 0.097 12.5 0.3 1.4 1 1 0 1 1 1 0 CG-1 domain PTR PF12789.7 EAX73533.1 - 3.4e-23 81.5 11.6 1.2e-16 60.5 1.9 3.7 4 0 0 4 4 4 2 Phage tail repeat like DUF240 PF03086.14 EAX73533.1 - 0.065 13.2 2.2 1.8 8.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4108 PF13390.6 EAX73534.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX73537.1 - 9.3e-42 142.9 7.8 7.3e-40 136.8 7.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DDR PF08841.10 EAX73538.1 - 0.11 11.4 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX73539.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Pox_A32 PF04665.12 EAX73540.1 - 3.2e-07 30.0 3.1 4.5e-07 29.6 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73540.1 - 0.0042 16.7 0.2 0.0055 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73540.1 - 0.052 13.0 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73540.1 - 0.056 13.2 0.3 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73540.1 - 0.084 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73540.1 - 0.17 11.9 2.2 1.2 9.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73540.1 - 0.47 10.7 8.3 5.3 7.3 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX73541.1 - 2.3e-25 89.4 10.4 9.4e-25 87.4 10.4 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73541.1 - 0.1 12.6 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX73541.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Shisa PF13908.6 EAX73542.1 - 7.2e-05 23.1 0.0 8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 EAX73542.1 - 0.004 17.4 0.1 0.0089 16.3 0.1 1.7 1 1 1 2 2 2 1 Glycophorin A SieB PF14163.6 EAX73542.1 - 0.15 11.5 0.4 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Epiglycanin_C PF14654.6 EAX73542.1 - 0.19 11.8 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region CYYR1 PF10873.8 EAX73542.1 - 3.7 8.0 11.5 0.13 12.7 4.0 2.4 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 PSP PF04046.16 EAX73543.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX73544.1 - 4e-32 110.1 14.7 4e-32 110.1 14.7 4.1 3 2 1 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX73544.1 - 0.018 14.7 1.1 0.037 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAX73545.1 - 0.083 12.8 1.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP ResIII PF04851.15 EAX73547.1 - 1.8e-05 24.8 0.5 2.9e-05 24.2 0.5 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73547.1 - 0.00033 20.5 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73547.1 - 0.0005 20.4 0.0 0.00075 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73547.1 - 0.0021 17.9 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73547.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73547.1 - 0.037 13.5 0.0 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX73547.1 - 0.092 12.4 0.1 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX73547.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX73547.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX73547.1 - 0.15 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX73547.1 - 0.2 11.2 1.6 0.15 11.5 0.3 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase PTR PF12789.7 EAX73550.1 - 1.6e-23 82.5 11.0 1.6e-23 82.5 11.0 4.1 4 1 1 5 5 4 1 Phage tail repeat like DUF4107 PF13389.6 EAX73551.1 - 6e-74 247.6 4.5 7e-74 247.4 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX73551.1 - 0.13 10.7 1.0 0.18 10.2 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DNA_pol_B_2 PF03175.13 EAX73557.1 - 7.9e-25 87.6 10.9 5.3e-24 84.9 10.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73557.1 - 0.11 12.5 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX73557.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) HECT PF00632.25 EAX73558.1 - 1.8e-21 77.0 0.4 2.3e-19 70.0 0.7 2.1 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DNA_pol_B_2 PF03175.13 EAX73559.1 - 3.4e-23 82.3 9.6 1.7e-22 79.9 9.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73559.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PTR PF12789.7 EAX73561.1 - 5.4e-11 42.4 21.6 6.6e-09 35.7 1.5 4.8 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX73561.1 - 0.016 14.9 14.1 0.11 12.1 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX73561.1 - 0.41 11.2 9.4 12 6.5 1.4 4.1 4 1 0 4 4 4 0 YmaF family Transposase_24 PF03004.14 EAX73561.1 - 1 9.4 6.2 0.84 9.7 1.7 2.4 1 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) ATR13 PF16829.5 EAX73561.1 - 1.2 9.6 5.1 1.8 9.0 2.3 2.3 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Phage_fiber PF03335.13 EAX73561.1 - 2.4 8.6 21.7 4.1 7.8 0.3 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat FliD_N PF02465.18 EAX73562.1 - 0.26 12.0 4.8 0.43 11.3 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX73562.1 - 1.7 7.3 3.9 2.1 7.0 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HC2 PF07382.11 EAX73563.1 - 3.2e-08 33.9 11.0 3.5e-08 33.8 11.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX73563.1 - 8.9e-05 22.6 1.6 0.00011 22.2 1.6 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) XAP5 PF04921.14 EAX73563.1 - 0.42 10.4 4.7 0.57 10.0 4.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Aurora-A_bind PF09041.10 EAX73563.1 - 2 8.6 8.5 3.2e+02 1.5 8.5 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX73563.1 - 3 7.9 5.1 1e+02 3.0 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) YvrJ PF12841.7 EAX73564.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Amidase02_C PF12123.8 EAX73565.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX73565.1 - 0.17 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX73566.1 - 6e-33 114.3 1.9 8.6e-33 113.8 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX73568.1 - 3.8e-07 30.6 0.3 7.6e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain TPR_MLP1_2 PF07926.12 EAX73569.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX73569.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX73569.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4107 PF13389.6 EAX73570.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73570.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta T5orf172 PF10544.9 EAX73571.1 - 0.00038 21.0 0.3 0.0011 19.4 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX73571.1 - 0.0063 16.1 0.5 0.076 12.5 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX73571.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 PaRep2a PF07903.11 EAX73574.1 - 0.086 12.7 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX73574.1 - 0.35 10.8 7.5 0.12 12.3 2.5 2.3 3 0 0 3 3 3 0 Spo12 family DUF4106 PF13388.6 EAX73575.1 - 6.8e-237 786.5 15.8 8e-237 786.3 15.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) FTCD_C PF04961.12 EAX73575.1 - 0.12 12.1 2.4 7.9 6.2 0.2 2.4 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Cas_Csa5 PF09702.10 EAX73577.1 - 1e-05 25.7 7.8 60 4.0 0.0 6.6 1 1 6 7 7 7 0 CRISPR-associated protein (Cas_Csa5) Retinin_C PF04527.12 EAX73577.1 - 0.0014 18.8 37.4 9.4 6.6 0.5 8.1 8 0 0 8 8 8 4 Drosophila Retinin like protein Phage_holin_6_1 PF09682.10 EAX73577.1 - 0.013 15.9 8.4 1.1e+02 3.2 0.1 6.1 1 1 7 8 8 8 0 Bacteriophage holin of superfamily 6 (Holin_LLH) FliG_C PF01706.16 EAX73577.1 - 0.025 14.8 18.0 47 4.2 0.1 6.6 1 1 6 7 7 7 0 FliG C-terminal domain UK PF02512.14 EAX73577.1 - 0.24 11.9 21.2 92 3.7 0.2 7.2 1 1 7 8 8 8 0 Virulence determinant TraC PF07820.12 EAX73577.1 - 0.76 10.1 5.5 85 3.6 0.2 4.1 1 1 4 5 5 5 0 TraC-like protein Pro_dh-DNA_bdg PF14850.6 EAX73577.1 - 1 9.9 17.1 5.1 7.7 1.2 3.6 1 1 4 5 5 5 0 DNA-binding domain of Proline dehydrogenase Cnd1 PF12717.7 EAX73577.1 - 8.8 6.4 21.2 16 5.5 1.4 3.6 1 1 3 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DNA_pol_B_2 PF03175.13 EAX73579.1 - 4.4e-16 58.8 3.7 8.3e-16 57.9 3.7 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX73579.1 - 0.015 14.6 0.5 0.021 14.1 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF2294 PF10057.9 EAX73580.1 - 0.018 15.1 4.7 2 8.6 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DsbC PF11412.8 EAX73580.1 - 0.073 13.1 4.3 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Disulphide bond corrector protein DsbC DUF1935 PF09149.10 EAX73580.1 - 0.097 13.1 6.0 0.14 12.6 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1935) Fucose_iso_C PF02952.17 EAX73580.1 - 0.099 12.3 1.0 0.3 10.8 0.2 1.9 1 1 1 2 2 2 0 L-fucose isomerase, C-terminal domain MlaD PF02470.20 EAX73580.1 - 0.11 12.9 5.3 2 8.8 0.8 3.0 1 1 2 3 3 3 0 MlaD protein FAM219A PF15260.6 EAX73580.1 - 0.16 12.3 5.8 3.3 8.1 1.4 2.4 1 1 1 2 2 2 0 Protein family FAM219A PS-DH PF14765.6 EAX73580.1 - 0.16 11.1 5.7 0.24 10.6 5.7 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase ETF PF01012.21 EAX73580.1 - 0.24 11.3 5.4 0.37 10.6 3.9 1.8 1 1 1 2 2 2 0 Electron transfer flavoprotein domain DUF4058 PF13267.6 EAX73580.1 - 0.99 8.8 8.9 1.3 8.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) KH_4 PF13083.6 EAX73580.1 - 1.1 9.2 3.8 4.7 7.2 0.1 2.9 1 1 2 3 3 3 0 KH domain MerB PF03243.15 EAX73580.1 - 1.7 8.8 11.0 5.5 7.1 3.9 2.6 1 1 2 3 3 3 0 Alkylmercury lyase Mem_trans PF03547.18 EAX73580.1 - 2.2 6.6 4.9 2.5 6.4 4.9 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF5077 PF16871.5 EAX73580.1 - 2.5 7.9 9.8 11 5.9 9.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5077) SURF2 PF05477.11 EAX73580.1 - 3.4 7.3 7.9 4.9 6.8 7.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF3332 PF11810.8 EAX73580.1 - 3.5 7.2 9.5 7 6.3 9.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) DUF2690 PF10901.8 EAX73580.1 - 5 7.5 7.3 4.4 7.7 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2690) TP53IP5 PF15331.6 EAX73580.1 - 7.8 6.6 9.1 9.3 6.3 9.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GPS2_interact PF15784.5 EAX73585.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73585.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3877 PF12993.7 EAX73587.1 - 0.052 13.4 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) RIH_assoc PF08454.11 EAX73587.1 - 0.17 11.7 1.2 0.41 10.5 0.2 2.2 2 1 1 3 3 3 0 RyR and IP3R Homology associated Pox_A32 PF04665.12 EAX73588.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73588.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73588.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73588.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX73589.1 - 4.2e-07 29.7 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX73591.1 - 1.3e-06 28.0 2.7 1.3e-06 28.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX73591.1 - 1.5e-05 25.1 1.2 2.8e-05 24.2 1.2 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX73591.1 - 3.3e-05 24.2 0.2 0.00044 20.5 0.2 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAX73591.1 - 0.00022 21.0 0.2 0.35 10.6 0.0 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX73591.1 - 0.00029 20.6 0.1 0.00054 19.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73591.1 - 0.0014 18.4 0.7 0.0037 17.1 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX73591.1 - 0.0041 16.8 0.5 0.025 14.2 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX73591.1 - 0.014 15.7 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX73591.1 - 0.073 12.6 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX73591.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4795 PF16043.5 EAX73591.1 - 0.55 9.8 7.2 0.17 11.5 2.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) JMY PF15871.5 EAX73592.1 - 0.03 13.6 0.4 0.048 13.0 0.4 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX73593.1 - 1.2e-68 231.1 2.4 1.4e-68 231.0 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73593.1 - 0.022 14.2 0.2 0.026 14.0 0.2 1.0 1 0 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX73593.1 - 0.14 12.6 1.1 0.37 11.3 1.1 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX73593.1 - 0.23 12.1 1.8 1.9 9.1 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) T5orf172 PF10544.9 EAX73594.1 - 9.7e-07 29.3 0.3 1.9e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73595.1 - 1.1e-27 96.1 1.1 1.6e-27 95.6 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73595.1 - 0.038 14.6 0.0 0.089 13.4 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF3040 PF11239.8 EAX73595.1 - 0.085 13.1 0.1 0.29 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Transposase_mut PF00872.18 EAX73596.1 - 0.0085 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DNA_pol_B_2 PF03175.13 EAX73597.1 - 5.2e-25 88.2 10.2 2.5e-24 86.0 10.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73597.1 - 0.1 12.6 0.0 1 9.4 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF1493 PF07377.12 EAX73598.1 - 0.058 13.9 0.5 0.15 12.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4106 PF13388.6 EAX73599.1 - 2.9e-262 870.1 18.1 3.2e-262 869.9 18.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73599.1 - 0.00096 19.4 0.2 0.024 14.9 0.3 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX73599.1 - 0.014 15.2 0.2 0.034 13.9 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Pox_D5 PF03288.16 EAX73600.1 - 3.9e-05 24.0 2.5 0.00018 21.9 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX73601.1 - 1.1e-58 197.2 6.0 1.2e-58 197.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX73602.1 - 0.021 14.6 0.0 0.022 14.5 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3464 PF11947.8 EAX73602.1 - 0.67 9.7 3.1 0.66 9.7 3.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX73602.1 - 1 9.3 5.3 1.8 8.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DDE_1 PF03184.19 EAX73603.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Styelin PF17562.2 EAX73603.1 - 0.0034 17.7 0.8 0.0065 16.8 0.8 1.4 1 0 0 1 1 1 1 Styelin dsDNA_bind PF01984.20 EAX73603.1 - 0.068 13.4 0.4 0.1 12.9 0.4 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain PapD_N PF00345.20 EAX73604.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73604.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4107 PF13389.6 EAX73605.1 - 2.5e-57 193.6 1.5 3.3e-57 193.2 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX73606.1 - 0.29 11.9 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX73606.1 - 8.1 6.4 8.5 8.7 6.3 8.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.22 EAX73608.1 - 7.8e-09 35.3 0.0 8.3e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX73608.1 - 2.6e-08 34.1 0.0 2.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX73608.1 - 0.00061 19.3 0.0 0.00062 19.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX73608.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 EAX73608.1 - 0.021 14.2 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX73608.1 - 0.03 14.7 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EAX73608.1 - 0.035 13.9 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EAX73608.1 - 0.036 14.0 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EAX73608.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAX73608.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX73608.1 - 0.086 13.1 0.0 0.086 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX73608.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol_B_2 PF03175.13 EAX73609.1 - 1.3e-08 34.2 0.8 2.7e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX73609.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX73609.1 - 0.16 12.0 0.0 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX73610.1 - 6.6e-157 520.2 12.7 8.2e-157 519.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Chordopox_G3 PF06129.12 EAX73613.1 - 0.023 15.4 0.7 0.039 14.6 0.3 1.6 2 0 0 2 2 2 0 Chordopoxvirus G3 protein HTH_Tnp_4 PF13613.6 EAX73613.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF3839 PF12943.7 EAX73614.1 - 6.8e-25 87.9 3.8 9.3e-25 87.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX73616.1 - 0.0083 15.8 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX73617.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX73617.1 - 0.18 11.6 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF563 PF04577.14 EAX73618.1 - 3.2e-21 76.4 0.0 3.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pox_A32 PF04665.12 EAX73619.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73619.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73619.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73619.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_D5 PF03288.16 EAX73620.1 - 4.4e-05 23.9 2.8 0.00034 21.1 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX73620.1 - 0.014 15.3 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX73620.1 - 0.015 15.9 0.1 0.03 14.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX73621.1 - 4.1e-58 195.4 8.5 4.6e-58 195.2 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX73622.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PTR PF12789.7 EAX73623.1 - 2.1e-11 43.7 16.2 3.1e-08 33.5 0.8 4.3 4 0 0 4 4 4 2 Phage tail repeat like DUF3417 PF11897.8 EAX73623.1 - 0.0047 17.4 2.0 0.1 13.0 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX73623.1 - 0.0091 15.7 3.9 1.9 8.2 0.4 3.0 2 1 1 3 3 3 2 Ethylene-responsive protein kinase Le-CTR1 CREPT PF16566.5 EAX73623.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.8 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour NPV_P10 PF05531.12 EAX73623.1 - 0.96 10.0 8.3 16 6.0 0.0 3.3 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF445 PF04286.12 EAX73623.1 - 3 7.6 10.1 4.1 7.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phage_fiber PF03335.13 EAX73623.1 - 3.7 8.0 16.5 9.6 6.7 0.1 4.8 4 0 0 4 4 4 0 Phage tail fibre repeat KilA-N PF04383.13 EAX73628.1 - 5.3e-42 142.2 0.1 5.3e-42 142.2 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX73628.1 - 0.03 14.5 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX73629.1 - 5.1e-07 30.2 0.3 1e-06 29.2 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF2939 PF11159.8 EAX73630.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73630.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX73631.1 - 0.049 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX73631.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX73632.1 - 2.8e-56 190.7 4.0 3.2e-56 190.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73632.1 - 0.022 14.2 0.2 0.026 14.0 0.2 1.0 1 0 0 1 1 1 0 Z1 domain Trypan_PARP PF05887.11 EAX73633.1 - 0.031 14.3 12.6 0.032 14.2 12.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2897 PF11446.8 EAX73635.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73636.1 - 1.5e-55 187.1 7.2 1.7e-55 186.9 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX73638.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73639.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX73640.1 - 5.7e-35 120.9 3.4 6.9e-35 120.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX73640.1 - 0.028 12.9 0.9 0.027 12.9 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX73641.1 - 3.8e-24 84.5 12.2 3.8e-24 84.5 12.2 2.7 3 0 0 3 3 3 1 Phage tail repeat like Med18 PF09637.10 EAX73642.1 - 0.062 13.1 0.1 0.075 12.9 0.1 1.0 1 0 0 1 1 1 0 Med18 protein Pox_A32 PF04665.12 EAX73643.1 - 2.6e-07 30.4 2.3 3.5e-07 29.9 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73643.1 - 0.0043 16.7 0.1 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73643.1 - 0.053 13.0 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73643.1 - 0.059 13.1 0.3 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73643.1 - 0.084 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX73643.1 - 0.18 11.8 2.2 1.3 9.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73643.1 - 0.51 10.6 8.4 5.5 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX73644.1 - 3.1e-120 400.1 11.4 3.9e-120 399.8 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73644.1 - 0.0054 17.2 2.4 1.8 9.0 0.0 3.2 2 1 1 3 3 3 3 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX73646.1 - 1.2e-06 28.2 2.7 1.2e-06 28.2 2.7 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX73646.1 - 4.9e-05 23.1 0.2 0.36 10.5 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX73646.1 - 0.00013 22.2 0.1 0.00089 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX73646.1 - 0.00021 21.3 4.1 0.00049 20.1 4.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73646.1 - 0.00066 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX73646.1 - 0.002 17.8 0.5 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX73646.1 - 0.0045 16.8 2.2 0.024 14.4 2.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73646.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX73646.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX73646.1 - 0.083 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX73646.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX73646.1 - 0.1 13.0 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX73646.1 - 0.67 10.2 4.6 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX73647.1 - 5.4e-47 160.3 3.8 6.1e-47 160.1 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX73648.1 - 4.4e-72 241.5 3.8 6.2e-72 241.0 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73648.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX73649.1 - 7.2e-51 173.0 2.5 8e-51 172.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4106 PF13388.6 EAX73650.1 - 3.7e-276 915.9 18.9 4.3e-276 915.7 18.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73650.1 - 0.013 15.8 0.1 0.61 10.4 0.2 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated DUF2939 PF11159.8 EAX73651.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73651.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX73652.1 - 0.017 15.2 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX73653.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73653.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2939 PF11159.8 EAX73654.1 - 0.015 15.7 0.5 0.018 15.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73654.1 - 2 7.4 3.5 1.9 7.4 3.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX73654.1 - 7.9 6.5 7.4 8.3 6.4 7.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDR PF08841.10 EAX73656.1 - 0.11 11.5 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Mito_fiss_reg PF05308.11 EAX73658.1 - 0.027 14.6 1.6 0.028 14.5 1.6 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73658.1 - 0.66 9.4 6.8 0.66 9.4 6.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4106 PF13388.6 EAX73660.1 - 4.7e-272 902.3 21.0 5.3e-272 902.2 21.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73660.1 - 0.00065 20.0 0.1 0.03 14.6 0.3 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated YppG PF14179.6 EAX73660.1 - 8.5 7.2 30.1 2.1 9.1 25.9 2.3 3 0 0 3 3 3 0 YppG-like protein YmaF PF12788.7 EAX73662.1 - 0.074 13.6 0.3 1.5 9.4 0.1 2.2 2 0 0 2 2 2 0 YmaF family DUF3839 PF12943.7 EAX73663.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HTH_29 PF13551.6 EAX73664.1 - 0.024 14.6 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX73664.1 - 0.038 14.3 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Transposase DNA_pol_B_2 PF03175.13 EAX73665.1 - 1.7e-11 43.7 0.3 1.7e-11 43.7 0.3 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX73665.1 - 0.031 13.6 0.2 0.043 13.1 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4404 PF14357.6 EAX73666.1 - 0.023 15.3 9.2 0.023 15.3 9.2 6.6 3 3 4 7 7 7 0 Domain of unknown function (DUF4404) HemX PF04375.14 EAX73666.1 - 0.04 13.2 65.8 0.36 10.1 8.5 5.0 1 1 4 5 5 5 0 HemX, putative uroporphyrinogen-III C-methyltransferase SF-assemblin PF06705.11 EAX73666.1 - 0.065 12.6 77.9 0.4 10.0 24.5 4.2 1 1 0 3 3 3 0 SF-assemblin/beta giardin Titin_Ig-rpts PF06582.12 EAX73666.1 - 0.55 10.2 3.1 29 4.7 0.2 2.8 2 0 0 2 2 2 0 Titin repeat Golgin_A5 PF09787.9 EAX73666.1 - 0.62 9.5 68.1 0.3 10.5 14.4 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 EAX73666.1 - 2.6 6.5 21.0 4.9 5.6 1.1 3.3 1 1 2 3 3 3 0 Fusaric acid resistance protein family YwqJ-deaminase PF14431.6 EAX73666.1 - 5.5 7.2 18.8 9 6.5 1.5 3.9 1 1 1 3 3 3 0 YwqJ-like deaminase Lebercilin PF15619.6 EAX73666.1 - 9.8 5.8 77.9 2.8 7.6 27.3 4.3 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF3839 PF12943.7 EAX73667.1 - 6e-80 268.2 9.5 7.8e-80 267.8 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX73668.1 - 1.8e-05 24.4 0.5 2.1e-05 24.1 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX73668.1 - 0.047 13.7 0.4 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Zot PF05707.12 EAX73668.1 - 0.066 12.8 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PapD_N PF00345.20 EAX73669.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX73670.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73670.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_D5 PF03288.16 EAX73671.1 - 8.2e-06 26.2 0.5 1.2e-05 25.7 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73671.1 - 0.046 14.4 0.2 0.061 13.9 0.2 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73671.1 - 0.075 13.0 0.3 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73672.1 - 4.6e-59 198.5 8.5 5.1e-59 198.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX73674.1 - 0.043 13.7 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX73675.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73675.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX73675.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX73675.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ank_2 PF12796.7 EAX73676.1 - 2.9e-81 268.1 32.9 2.1e-16 60.3 1.7 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX73676.1 - 6.9e-53 176.4 12.7 4.9e-12 46.1 0.2 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX73676.1 - 2.4e-48 161.6 14.3 1.8e-10 40.8 0.1 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX73676.1 - 3.4e-47 152.9 6.7 5.1e-06 26.4 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX73676.1 - 4.4e-45 150.2 11.4 1.4e-07 31.7 0.3 7.3 8 0 0 8 8 8 6 Ankyrin repeat MetallophosN PF16371.5 EAX73676.1 - 9.4e-07 29.0 0.0 33 4.8 0.0 5.9 1 1 5 6 6 6 0 N terminal of Calcineurin-like phosphoesterase Glyco_hydro_20b PF02838.15 EAX73676.1 - 0.0001 23.1 2.6 3.4 8.5 0.1 4.2 1 1 3 4 4 4 2 Glycosyl hydrolase family 20, domain 2 Stap_Strp_toxin PF01123.20 EAX73676.1 - 0.00042 21.1 6.5 15 6.5 0.1 4.9 1 1 3 5 5 5 0 Staphylococcal/Streptococcal toxin, OB-fold domain Arg_repressor PF01316.21 EAX73676.1 - 0.0012 18.5 0.7 42 4.0 0.0 4.9 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain DUF3718 PF12514.8 EAX73676.1 - 0.0013 18.8 10.4 1.6 9.0 0.1 5.7 3 2 4 7 7 7 1 Protein of unknown function (DUF3718) DUF3677 PF12432.8 EAX73676.1 - 0.0013 19.0 0.0 83 3.6 0.0 5.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3677) RGP PF03214.13 EAX73676.1 - 0.0029 16.8 0.0 14 4.7 0.0 4.3 1 1 5 6 6 6 0 Reversibly glycosylated polypeptide DUF4231 PF14015.6 EAX73676.1 - 0.0042 17.5 0.0 55 4.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) S4 PF01479.25 EAX73676.1 - 0.0043 16.7 0.1 44 3.9 0.0 4.9 6 0 0 6 6 6 0 S4 domain ACD PF16671.5 EAX73676.1 - 0.016 13.5 0.6 4.4 5.5 0.0 2.7 1 1 3 4 4 4 0 Actin cross-linking domain Herpes_UL36 PF03586.13 EAX73676.1 - 0.023 14.0 0.2 2.5 7.4 0.0 2.8 2 1 1 3 3 3 0 Herpesvirus UL36 tegument protein DUF1861 PF08950.10 EAX73676.1 - 0.05 12.8 0.0 38 3.4 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1861) DUF348 PF03990.14 EAX73676.1 - 0.078 12.7 4.6 1.5e+02 2.2 0.0 5.8 7 0 0 7 7 7 0 G5-linked-Ubiquitin-like domain EF-hand_1 PF00036.32 EAX73677.1 - 2e-26 89.5 15.3 1.9e-07 30.1 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAX73677.1 - 2.2e-22 77.0 16.9 3.8e-06 26.4 0.3 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EAX73677.1 - 2.3e-20 72.8 12.0 2.2e-12 47.2 2.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX73677.1 - 8e-18 63.1 15.3 0.00057 19.3 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAX73677.1 - 6.7e-13 48.3 10.3 6.1e-06 26.0 1.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EAX73677.1 - 2e-06 27.7 7.1 0.088 12.8 0.1 3.2 2 1 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand IF2_N PF04760.15 EAX73677.1 - 0.00013 21.7 1.6 0.046 13.5 0.0 3.5 3 1 1 4 4 4 1 Translation initiation factor IF-2, N-terminal region EF-hand_10 PF14788.6 EAX73677.1 - 0.0005 19.9 7.3 0.0033 17.3 0.8 3.0 3 1 0 3 3 3 1 EF hand PRESAN PF09687.10 EAX73677.1 - 0.004 17.7 1.0 0.68 10.5 0.1 2.5 1 1 1 2 2 2 1 Plasmodium RESA N-terminal SPARC_Ca_bdg PF10591.9 EAX73677.1 - 0.017 15.4 2.7 0.063 13.6 0.5 2.5 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EAX73677.1 - 0.067 13.5 0.0 5.7 7.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain UPF0154 PF03672.13 EAX73677.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) p25-alpha PF05517.12 EAX73677.1 - 0.11 12.6 1.7 0.57 10.3 2.4 1.8 2 0 0 2 2 2 0 p25-alpha SCF PF02404.15 EAX73677.1 - 0.16 11.3 1.3 0.23 10.8 1.3 1.2 1 0 0 1 1 1 0 Stem cell factor DUF3839 PF12943.7 EAX73679.1 - 1.1e-159 529.3 13.4 1.5e-159 528.8 13.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX73679.1 - 0.22 11.8 4.3 13 6.2 0.0 3.8 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX73679.1 - 3.9 8.0 8.1 2.6 8.6 0.8 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5305 PF17231.2 EAX73680.1 - 0.0031 16.9 0.4 0.0035 16.8 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) PRIMA1 PF16101.5 EAX73680.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CEND1 PF15677.5 EAX73680.1 - 0.01 16.4 0.2 0.032 14.8 0.2 1.8 1 1 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 DUF4064 PF13273.6 EAX73680.1 - 0.014 15.7 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2749 PF10907.8 EAX73680.1 - 0.015 15.4 1.1 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) TMEM154 PF15102.6 EAX73680.1 - 0.025 14.5 0.7 0.035 14.0 0.7 1.3 1 1 0 1 1 1 0 TMEM154 protein family GRA6 PF05084.13 EAX73680.1 - 0.029 14.3 3.1 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 Granule antigen protein (GRA6) EphA2_TM PF14575.6 EAX73680.1 - 0.039 14.8 1.2 0.043 14.7 0.2 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 EAX73680.1 - 0.067 13.6 2.5 0.11 13.0 2.5 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Baculo_11_kDa PF06143.11 EAX73680.1 - 0.092 12.3 0.3 0.14 11.7 0.3 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.6 EAX73680.1 - 0.1 12.9 0.3 0.15 12.3 0.3 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GPS2_interact PF15784.5 EAX73681.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73681.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BRO1 PF03097.18 EAX73682.1 - 0.044 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX73682.1 - 0.71 9.4 4.3 2.3 7.8 4.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX73685.1 - 4.6e-43 146.6 3.0 5e-43 146.4 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX73685.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF2897 PF11446.8 EAX73686.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX73687.1 - 1.8e-05 24.8 0.6 3e-05 24.1 0.6 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73687.1 - 0.0003 20.6 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73687.1 - 0.00043 20.6 0.0 0.00065 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73687.1 - 0.0019 18.0 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73687.1 - 0.007 16.7 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73687.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX73687.1 - 0.083 12.5 0.2 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX73687.1 - 0.093 12.3 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX73687.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX73687.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX73687.1 - 0.25 10.8 2.4 0.12 11.9 0.5 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase PTR PF12789.7 EAX73688.1 - 2.9e-16 59.3 2.5 2.9e-16 59.3 2.5 5.0 4 2 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX73688.1 - 0.01 15.5 1.0 0.01 15.5 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX73688.1 - 0.018 14.7 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX73688.1 - 0.039 13.9 2.5 1.5 8.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4107 PF13389.6 EAX73689.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX73689.1 - 0.1 11.0 1.1 0.14 10.6 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase MetW PF07021.12 EAX73690.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW EF-hand_10 PF14788.6 EAX73692.1 - 0.0028 17.5 0.1 0.0079 16.0 0.1 1.8 1 0 0 1 1 1 1 EF hand PapD_N PF00345.20 EAX73693.1 - 0.057 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73693.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Amidase02_C PF12123.8 EAX73694.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase YmaF PF12788.7 EAX73695.1 - 0.047 14.2 1.2 0.2 12.2 1.2 1.8 1 1 0 1 1 1 0 YmaF family Pox_A32 PF04665.12 EAX73696.1 - 4.1e-07 29.7 2.2 5.9e-07 29.2 2.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73696.1 - 0.0045 16.7 0.1 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73696.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73696.1 - 0.065 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX73696.1 - 0.078 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX73696.1 - 0.14 12.6 3.3 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX73696.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73696.1 - 0.53 10.5 8.3 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX73697.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX73697.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF4107 PF13389.6 EAX73698.1 - 5.1e-34 117.8 1.8 7.3e-34 117.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX73699.1 - 9.6e-41 138.1 1.0 1.6e-40 137.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73699.1 - 0.039 14.6 0.5 0.15 12.7 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family POX PF07526.11 EAX73699.1 - 0.76 10.3 3.7 13 6.4 0.2 2.3 2 0 0 2 2 2 0 Associated with HOX PTR PF12789.7 EAX73700.1 - 3.5e-36 123.1 21.7 3.1e-31 107.2 13.3 4.3 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX73700.1 - 0.025 14.3 1.0 0.05 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX73701.1 - 0.029 14.8 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73701.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX73702.1 - 4.2e-152 504.5 13.3 5.2e-152 504.1 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73702.1 - 0.088 13.3 2.5 1.8 9.1 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX73702.1 - 0.38 11.1 3.8 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX73703.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73704.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX73705.1 - 0.02 15.4 1.1 0.036 14.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX73707.1 - 1e-07 31.7 1.1 1.3e-07 31.4 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73707.1 - 0.0055 16.4 0.1 0.0059 16.3 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX73707.1 - 0.074 13.0 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX73707.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DNA_pol_B_2 PF03175.13 EAX73708.1 - 1.6e-22 80.0 3.7 2.3e-22 79.5 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral OrsD PF12013.8 EAX73710.1 - 0.13 12.7 3.3 0.26 11.8 3.3 1.4 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D PyrI_C PF02748.15 EAX73710.1 - 1.8 8.5 7.9 1.3 8.9 1.1 2.8 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Colicin_Pyocin PF01320.18 EAX73711.1 - 0.026 14.6 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein DpnI_C PF17726.1 EAX73711.1 - 0.066 13.3 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain MtrG PF04210.13 EAX73712.1 - 0.00097 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4107 PF13389.6 EAX73715.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX73716.1 - 7.1e-80 267.9 9.4 9.4e-80 267.6 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73716.1 - 0.075 13.6 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Mlf1IP PF10248.9 EAX73717.1 - 2.7e-12 47.0 2.8 2.7e-12 47.0 2.8 1.7 2 1 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein CDC27 PF09507.10 EAX73717.1 - 1.2 8.4 32.7 1.4 8.2 32.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WRNPLPNID PF15017.6 EAX73717.1 - 9.9 7.1 22.1 0.82 10.6 7.0 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box His_Phos_2 PF00328.22 EAX73718.1 - 2.1e-11 43.8 0.0 3.7e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) T5orf172 PF10544.9 EAX73719.1 - 6.5e-06 26.6 0.1 1.6e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73719.1 - 0.036 13.9 0.2 0.15 12.0 0.1 2.2 2 1 0 2 2 2 0 KilA-N domain C2-C2_1 PF11618.8 EAX73720.1 - 0.021 14.9 0.1 0.022 14.8 0.1 1.0 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 TMP PF05017.14 EAX73721.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX73721.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX73722.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP YmaF PF12788.7 EAX73724.1 - 0.15 12.6 1.4 2.6 8.6 1.4 2.1 1 1 1 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX73724.1 - 2.3 8.6 8.7 2.7 8.4 0.6 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat DDE_1 PF03184.19 EAX73727.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease KilA-N PF04383.13 EAX73728.1 - 1.4e-35 121.5 0.6 2.9e-35 120.5 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73728.1 - 0.014 16.0 0.1 0.035 14.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX73728.1 - 0.35 10.9 4.6 2.6 8.1 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DNA_pol_B_2 PF03175.13 EAX73729.1 - 9.3e-09 34.7 1.4 5.3e-08 32.2 1.4 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX73729.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Gly-zipper_Omp PF13488.6 EAX73730.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX73730.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX73730.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX73732.1 - 4.1e-37 126.0 20.7 2.1e-34 117.3 14.4 4.3 2 2 1 3 3 3 2 Phage tail repeat like PBP5_C PF07943.13 EAX73732.1 - 0.016 15.4 1.0 0.08 13.2 0.1 2.3 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DUF4116 PF13475.6 EAX73732.1 - 0.035 13.8 0.9 0.074 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Pox_D5 PF03288.16 EAX73733.1 - 0.0001 22.7 1.5 0.00016 22.1 1.5 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73733.1 - 0.001 19.6 0.1 0.0016 19.0 0.1 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73733.1 - 0.024 14.6 1.1 0.044 13.7 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Adeno_52K PF03052.15 EAX73733.1 - 0.15 11.5 0.1 0.79 9.1 0.1 1.8 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa DUF4108 PF13390.6 EAX73734.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX73735.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX73736.1 - 0.017 15.5 0.5 0.021 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73736.1 - 1.4 8.9 5.8 1.5 8.8 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX73736.1 - 1.5 7.8 2.7 1.6 7.7 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein MULE PF10551.9 EAX73737.1 - 9e-11 42.0 1.1 1.6e-10 41.2 0.2 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX73737.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family KilA-N PF04383.13 EAX73739.1 - 3.5e-31 107.3 0.5 9.7e-31 105.9 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF4106 PF13388.6 EAX73741.1 - 5.2e-253 839.6 17.9 6.2e-253 839.4 17.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73741.1 - 0.015 15.6 0.1 0.7 10.2 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated Phage_fiber_2 PF03406.13 EAX73741.1 - 4 7.1 6.5 0.82 9.3 2.3 2.0 2 0 0 2 2 2 0 Phage tail fibre repeat FAS_N PF17828.1 EAX73742.1 - 0.0085 16.1 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73743.1 - 0.027 14.9 0.3 0.037 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3839 PF12943.7 EAX73744.1 - 1.3e-16 60.8 3.4 2e-16 60.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX73744.1 - 0.092 13.2 0.9 0.48 10.9 0.1 2.0 1 1 0 2 2 2 0 Cell division protein ZapB FAS_N PF17828.1 EAX73745.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX73745.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX73746.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73746.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RFX_DNA_binding PF02257.15 EAX73747.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX73747.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX73747.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DNA_pol_B_2 PF03175.13 EAX73749.1 - 3e-24 85.7 7.5 1.7e-23 83.3 7.5 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX73749.1 - 0.12 12.3 0.1 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Pox_D5 PF03288.16 EAX73750.1 - 0.00011 22.7 3.2 0.00068 20.1 3.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX73750.1 - 0.096 12.7 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73751.1 - 3.4e-61 205.4 5.0 3.7e-61 205.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX73751.1 - 0.12 12.7 0.1 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX73752.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX73752.1 - 0.98 9.3 3.4 1.8 8.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73753.1 - 5.7e-51 172.2 5.5 6.3e-51 172.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX73754.1 - 9.9e-07 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX73755.1 - 4.7e-10 38.9 3.2 3.3e-09 36.1 2.5 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX73755.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DNA_pol_B_2 PF03175.13 EAX73756.1 - 9.9e-23 80.7 4.7 1.4e-22 80.2 4.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX73757.1 - 0.024 15.1 1.5 0.031 14.7 0.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73757.1 - 0.69 10.0 3.8 21 5.3 0.4 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX73758.1 - 8.9e-114 371.6 80.9 1.2e-34 118.1 16.5 5.7 3 1 3 6 6 6 4 Phage tail repeat like AviRa PF11599.8 EAX73758.1 - 0.29 10.6 3.4 1 8.8 0.5 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF2785 PF10978.8 EAX73758.1 - 1.6 8.5 5.4 1.6 8.5 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) PH_TFIIH PF08567.11 EAX73758.1 - 1.8 8.9 7.6 40 4.6 0.1 4.4 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF4108 PF13390.6 EAX73759.1 - 1.9e-61 206.2 7.3 2.1e-61 206.0 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX73760.1 - 0.57 10.1 3.8 1.1 9.2 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX73761.1 - 8.2e-07 29.5 0.3 1.6e-06 28.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX73763.1 - 4.2e-08 32.9 1.0 5e-08 32.7 1.0 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73763.1 - 0.0041 16.8 0.1 0.0045 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73763.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73763.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX73764.1 - 4.1e-10 39.5 0.1 5.1e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain LRR_5 PF13306.6 EAX73765.1 - 1.4e-21 76.8 5.6 2.5e-21 76.0 5.6 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX73765.1 - 0.069 12.9 0.0 0.68 9.7 0.0 2.2 1 1 2 3 3 3 0 Leucine rich repeat DUF1440 PF07274.12 EAX73765.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) PTR PF12789.7 EAX73766.1 - 1e-28 99.1 12.2 1e-28 99.1 12.2 3.6 5 1 0 5 5 5 1 Phage tail repeat like Imm32 PF15566.6 EAX73766.1 - 0.39 10.6 2.9 5.7 6.8 0.3 3.0 1 1 1 2 2 2 0 Immunity protein 32 Phage_fiber PF03335.13 EAX73766.1 - 0.43 10.9 21.4 13 6.3 0.2 5.4 5 0 0 5 5 5 0 Phage tail fibre repeat YmaF PF12788.7 EAX73766.1 - 0.74 10.4 15.6 17 6.0 6.4 3.5 2 2 0 2 2 2 0 YmaF family DUF4795 PF16043.5 EAX73766.1 - 4.7 6.7 10.3 2.1 7.9 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX73769.1 - 5.5e-55 185.2 7.3 6.1e-55 185.1 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DAO_C PF16901.5 EAX73770.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF3464 PF11947.8 EAX73770.1 - 0.15 11.8 3.5 0.15 11.8 3.5 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX73770.1 - 0.61 10.0 5.3 0.77 9.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S49_N PF08496.10 EAX73770.1 - 4.6 7.3 6.5 4.6 7.3 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 EAX73770.1 - 5.9 7.6 4.8 6.6 7.4 4.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3839 PF12943.7 EAX73772.1 - 1.5e-31 109.7 1.8 2.4e-31 109.0 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Lectin_legB PF00139.19 EAX73772.1 - 0.0058 16.2 0.3 0.24 10.9 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX73772.1 - 0.0068 16.9 0.5 0.02 15.4 0.1 2.1 3 0 0 3 3 3 1 T5orf172 domain DUF3839 PF12943.7 EAX73773.1 - 3.2e-107 357.5 8.0 3.6e-107 357.3 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GPS2_interact PF15784.5 EAX73775.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73775.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX73776.1 - 4.2e-65 215.7 45.5 1.4e-25 89.1 13.2 5.3 3 2 1 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX73776.1 - 0.014 15.1 0.2 0.094 12.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX73776.1 - 0.44 10.1 21.0 0.012 15.2 9.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX73776.1 - 0.63 10.4 8.2 43 4.5 0.1 4.8 2 2 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain Transposase_24 PF03004.14 EAX73776.1 - 2.6 8.2 13.5 0.16 12.1 1.5 3.2 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) Amidase02_C PF12123.8 EAX73777.1 - 0.0039 16.8 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase AAA_11 PF13086.6 EAX73779.1 - 0.0028 17.5 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX73779.1 - 0.0059 16.9 0.0 0.0097 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73779.1 - 0.016 14.7 0.1 0.019 14.5 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX73779.1 - 0.017 15.1 0.3 0.023 14.7 0.3 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX73779.1 - 0.027 14.8 0.1 0.041 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX73779.1 - 0.037 13.6 0.0 0.043 13.4 0.0 1.2 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX73779.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein T5orf172 PF10544.9 EAX73780.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain NPA PF16469.5 EAX73782.1 - 0.084 13.5 0.3 5.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 DUF4108 PF13390.6 EAX73783.1 - 5.1e-63 211.3 6.5 5.7e-63 211.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX73785.1 - 6.7e-78 261.5 9.8 8.9e-78 261.1 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73785.1 - 0.089 12.6 0.9 0.3 10.9 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PSP PF04046.16 EAX73787.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX73788.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX73789.1 - 9.5e-33 113.6 2.7 1.1e-32 113.5 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73789.1 - 0.11 12.9 0.8 0.13 12.7 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PSP PF04046.16 EAX73790.1 - 0.051 13.5 0.6 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73791.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX73792.1 - 6.3e-157 520.2 14.5 7.7e-157 520.0 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX73792.1 - 0.08 13.4 1.7 0.15 12.5 0.3 1.9 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX73792.1 - 0.1 12.1 0.1 0.37 10.3 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX73792.1 - 0.97 9.9 6.6 4.3 7.9 0.3 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX73793.1 - 3e-63 212.0 6.6 3.4e-63 211.8 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX73794.1 - 1.9e-05 25.0 2.5 9.5e-05 22.8 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX73794.1 - 0.034 13.2 1.2 0.049 12.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX73794.1 - 0.039 14.6 0.2 0.082 13.5 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain YpsA PF06908.11 EAX73794.1 - 0.063 13.3 1.0 0.12 12.4 0.3 1.7 2 0 0 2 2 2 0 YspA SLOG family PTR PF12789.7 EAX73795.1 - 6.9e-13 48.5 22.5 2.5e-07 30.6 0.9 5.0 4 1 1 5 5 5 2 Phage tail repeat like DUF3417 PF11897.8 EAX73795.1 - 0.0075 16.7 1.4 0.27 11.7 0.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX73795.1 - 0.0083 15.9 4.1 2 8.1 0.3 3.1 2 1 1 3 3 3 2 Ethylene-responsive protein kinase Le-CTR1 NPV_P10 PF05531.12 EAX73795.1 - 0.12 12.9 8.7 1.5 9.3 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF445 PF04286.12 EAX73795.1 - 1.5 8.6 8.8 2.1 8.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Flavodoxin_2 PF02525.17 EAX73797.1 - 1.6e-10 41.1 0.2 1.7e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_2 PF02525.17 EAX73798.1 - 8.9e-09 35.3 0.0 9.2e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold DUF257 PF03192.13 EAX73799.1 - 0.0014 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 PTR PF12789.7 EAX73800.1 - 4.4e-65 215.6 46.1 4.7e-32 109.8 14.3 4.7 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX73800.1 - 0.061 13.1 0.5 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX73800.1 - 0.24 11.7 6.4 26 5.2 0.2 4.3 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF1248 PF06852.12 EAX73801.1 - 0.12 11.8 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Pox_D5 PF03288.16 EAX73802.1 - 6.9e-05 23.3 3.7 0.00056 20.4 3.7 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73802.1 - 0.072 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX73803.1 - 1.9e-10 40.2 2.3 6.3e-10 38.5 2.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX73803.1 - 0.1 11.3 2.0 4.4 5.9 1.8 3.0 2 1 0 2 2 2 0 DNA polymerase family B Lac_bphage_repr PF06543.12 EAX73803.1 - 0.13 12.2 0.0 0.93 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4107 PF13389.6 EAX73804.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX73805.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF3839 PF12943.7 EAX73806.1 - 2.9e-40 138.2 5.0 4.2e-40 137.7 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX73806.1 - 0.1 12.1 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX73806.1 - 0.12 12.8 0.2 1.2 9.7 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX73806.1 - 0.44 11.0 3.1 1.3 9.4 1.4 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF1493 PF07377.12 EAX73807.1 - 0.024 15.1 0.5 0.047 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2584 PF10763.9 EAX73808.1 - 0.17 12.0 3.4 1.1 9.4 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2584) DUF1935 PF09149.10 EAX73808.1 - 0.22 11.9 6.4 0.17 12.3 2.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1935) Mem_trans PF03547.18 EAX73808.1 - 0.23 9.8 2.5 0.24 9.7 2.5 1.2 1 0 0 1 1 1 0 Membrane transport protein FAM219A PF15260.6 EAX73808.1 - 0.55 10.6 11.5 3 8.2 3.4 2.4 1 1 1 2 2 2 0 Protein family FAM219A MlaD PF02470.20 EAX73808.1 - 0.6 10.4 6.8 4.6 7.6 0.7 3.1 2 1 1 3 3 3 0 MlaD protein PS-DH PF14765.6 EAX73808.1 - 1.9 7.7 11.1 6 6.0 5.9 1.9 1 1 1 2 2 2 0 Polyketide synthase dehydratase Peptidase_S55 PF05580.12 EAX73808.1 - 3.6 7.5 8.9 5.1 7.0 8.9 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 Pkinase PF00069.25 EAX73810.1 - 4.8e-26 91.7 0.1 5.6e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX73810.1 - 3.1e-17 62.7 0.0 3.7e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase CbtA_toxin PF06755.12 EAX73810.1 - 0.062 13.3 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system TMP PF05017.14 EAX73811.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX73812.1 - 0.029 14.9 0.4 0.06 13.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73812.1 - 0.27 11.3 2.1 9.1 6.4 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX73814.1 - 0.058 14.0 8.2 2.2 9.3 1.3 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX73814.1 - 4.4 7.3 7.9 4.6 7.2 7.9 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX73815.1 - 0.087 12.7 0.7 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX73816.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX73816.1 - 0.064 13.4 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF2408 PF10303.9 EAX73816.1 - 0.088 13.4 0.5 0.1 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX73816.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 PapD_N PF00345.20 EAX73818.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4795 PF16043.5 EAX73819.1 - 0.0023 17.6 4.5 0.014 15.0 4.7 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX73819.1 - 1.7 9.0 6.3 7.1 7.1 0.7 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat ResIII PF04851.15 EAX73821.1 - 2.3e-05 24.5 0.9 3.7e-05 23.8 0.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73821.1 - 0.00028 20.7 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73821.1 - 0.00037 20.8 0.0 0.00063 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73821.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73821.1 - 0.0058 17.0 0.0 0.0083 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73821.1 - 0.036 13.5 0.1 0.079 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX73821.1 - 0.054 13.2 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX73821.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX73821.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SATase_N PF06426.14 EAX73824.1 - 0.0053 17.1 5.8 6.4 7.2 0.1 3.7 1 1 3 4 4 4 1 Serine acetyltransferase, N-terminal Peptidase_S24 PF00717.23 EAX73824.1 - 0.019 14.9 17.8 8.3 6.4 1.0 4.6 1 1 3 4 4 4 0 Peptidase S24-like DUF5301 PF17225.3 EAX73824.1 - 0.033 14.6 12.4 3.5 8.1 8.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Atg31 PF09795.9 EAX73824.1 - 0.038 14.0 33.8 3.1 7.8 3.5 4.2 1 1 4 5 5 5 0 Autophagy-related protein 31 DUF1287 PF06940.11 EAX73824.1 - 0.32 10.7 3.6 9.4 5.9 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1287) Pox_A32 PF04665.12 EAX73826.1 - 4.3e-08 32.9 1.4 4.4e-08 32.9 1.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73826.1 - 0.0021 17.7 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73826.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73826.1 - 0.093 12.7 0.5 0.96 9.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1269 PF06897.12 EAX73827.1 - 0.51 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PapD_N PF00345.20 EAX73828.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX73828.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HNH_3 PF13392.6 EAX73830.1 - 2.3e-08 33.6 0.2 4e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Pox_A32 PF04665.12 EAX73831.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73831.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73831.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73831.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX73832.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein RL10P_insert PF17777.1 EAX73834.1 - 0.0016 18.4 1.1 0.073 13.1 0.1 2.1 1 1 1 2 2 2 2 Insertion domain in 60S ribosomal protein L10P DUF3976 PF13121.6 EAX73834.1 - 3 8.0 12.8 1.3e+02 2.9 0.1 5.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3976) DUF3839 PF12943.7 EAX73835.1 - 5.7e-78 261.7 11.6 7.3e-78 261.4 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73835.1 - 0.052 14.1 0.3 0.088 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) P4Ha_N PF08336.11 EAX73835.1 - 0.064 13.3 1.0 2.5 8.1 0.0 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pox_A32 PF04665.12 EAX73836.1 - 5.2e-07 29.4 2.3 5.2e-07 29.4 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX73836.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX73836.1 - 4.4e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX73836.1 - 0.00018 21.6 3.5 0.00037 20.5 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73836.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73836.1 - 0.0015 18.4 0.6 0.003 17.4 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX73836.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX73836.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX73836.1 - 0.073 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX73836.1 - 0.092 13.2 0.1 0.76 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX73836.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX73836.1 - 0.39 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX73838.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Ank_4 PF13637.6 EAX73839.1 - 1.5e-05 25.5 0.0 1.5e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX73839.1 - 0.0094 16.2 0.0 0.011 16.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX73839.1 - 0.022 15.2 0.0 7.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 EAX73839.1 - 0.032 14.7 0.0 2.8 8.8 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EAX73839.1 - 0.059 14.0 0.1 0.073 13.7 0.1 1.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF2897 PF11446.8 EAX73840.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73841.1 - 4.9e-63 211.3 5.8 5.5e-63 211.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX73842.1 - 2e-62 210.8 4.6 2.8e-62 210.3 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX73842.1 - 0.046 14.7 0.4 0.082 13.9 0.4 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PRD PF00874.20 EAX73842.1 - 0.062 13.6 0.2 0.21 11.9 0.1 2.0 1 1 1 2 2 2 0 PRD domain APC_u14 PF16635.5 EAX73842.1 - 0.17 12.5 2.0 0.3 11.6 2.0 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr T5orf172 PF10544.9 EAX73843.1 - 3.7e-06 27.4 0.3 1e-05 26.0 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73843.1 - 0.017 15.0 0.1 0.078 12.8 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX73843.1 - 0.21 11.1 0.9 2.3 7.7 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain EpuA PF11772.8 EAX73844.1 - 0.0049 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta DUF3781 PF12636.7 EAX73845.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF1493 PF07377.12 EAX73846.1 - 0.03 14.8 0.7 0.053 14.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX73847.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73848.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX73849.1 - 6.3e-57 192.8 4.3 7.3e-57 192.6 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73849.1 - 0.036 13.6 0.2 0.041 13.4 0.2 1.0 1 0 0 1 1 1 0 Z1 domain DUF3839 PF12943.7 EAX73850.1 - 1.9e-156 518.6 13.7 2.4e-156 518.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73850.1 - 0.066 13.1 0.8 0.28 11.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX73850.1 - 0.074 13.3 0.6 1.4 9.2 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX73850.1 - 0.11 12.9 0.4 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX73850.1 - 1.3 9.6 7.6 2 8.9 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX73852.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73852.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73852.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73852.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX73853.1 - 3.2e-14 52.7 0.3 3.2e-14 52.7 0.3 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX73853.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF5623 PF18536.1 EAX73856.1 - 0.075 13.3 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX73856.1 - 0.18 11.7 5.6 0.15 12.0 2.9 2.1 2 1 0 2 2 2 0 Spo12 family Pox_D5 PF03288.16 EAX73858.1 - 2.9e-05 24.5 2.3 0.00017 22.0 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73858.1 - 0.03 14.9 0.1 0.058 14.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73858.1 - 0.092 12.7 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX73861.1 - 4.6e-07 29.6 0.0 6e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX73863.1 - 5.5e-10 39.1 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain EssA PF10661.9 EAX73863.1 - 1.8 8.4 9.8 4.5 7.1 9.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX73864.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73864.1 - 0.08 13.5 0.5 0.094 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRE_C2HC PF07530.11 EAX73864.1 - 0.082 13.0 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers LD_cluster2 PF18163.1 EAX73864.1 - 0.098 12.2 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX73864.1 - 0.16 12.5 1.2 0.76 10.3 0.3 2.3 2 1 1 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX73864.1 - 0.34 11.3 2.7 1.1 9.6 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4106 PF13388.6 EAX73865.1 - 5.6e-206 684.7 30.7 1.2e-205 683.5 30.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX73865.1 - 0.37 10.6 1.6 0.49 10.2 0.1 1.9 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) PapD_N PF00345.20 EAX73867.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX73867.1 - 0.071 13.1 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) SIR2 PF02146.17 EAX73868.1 - 1.6e-40 138.9 0.0 2.2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EAX73868.1 - 0.0059 16.3 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF4106 PF13388.6 EAX73870.1 - 2e-246 817.9 21.2 2.3e-246 817.7 21.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73870.1 - 0.012 15.9 0.1 0.6 10.4 0.2 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX73870.1 - 0.014 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PSP PF04046.16 EAX73872.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX73873.1 - 3.3e-253 840.3 25.7 2.3e-251 834.2 25.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73873.1 - 0.00074 19.8 0.2 0.029 14.7 0.4 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX73873.1 - 0.0061 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) Peptidase_S28 PF05577.12 EAX73873.1 - 0.86 8.3 5.0 1.3 7.7 5.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 KilA-N PF04383.13 EAX73874.1 - 1.8e-34 117.9 1.4 2.3e-34 117.6 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73874.1 - 0.015 15.9 0.0 0.036 14.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX73875.1 - 3.6e-08 33.2 1.2 4.1e-08 33.0 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73875.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX73875.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73875.1 - 0.088 12.8 0.3 0.7 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) ResIII PF04851.15 EAX73877.1 - 5.3e-05 23.3 2.4 9.6e-05 22.4 2.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73877.1 - 0.00032 20.5 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX73877.1 - 0.00039 20.7 0.0 0.0007 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX73877.1 - 0.00066 19.5 1.0 0.0019 18.0 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73877.1 - 0.0067 16.8 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73877.1 - 0.042 13.3 0.1 0.099 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX73877.1 - 0.043 13.5 0.3 0.27 10.9 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein DUF1827 PF08860.10 EAX73877.1 - 0.12 12.6 4.3 3.5 7.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX73877.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX73877.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX73877.1 - 0.8 10.2 4.6 0.31 11.5 1.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4106 PF13388.6 EAX73878.1 - 9.5e-69 232.6 2.9 9.5e-69 232.6 2.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Ribosomal_L18_c PF14204.6 EAX73878.1 - 1.3 10.0 10.3 7.9 7.5 2.3 3.8 2 1 0 2 2 2 0 Ribosomal L18 C-terminal region PSP PF04046.16 EAX73879.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX73880.1 - 0.062 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX73882.1 - 5.4e-55 185.3 5.6 5.9e-55 185.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX73884.1 - 2.3e-05 24.5 0.1 2.9e-05 24.2 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73884.1 - 0.00041 20.1 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73884.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX73884.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX73884.1 - 0.0055 17.1 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX73884.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX73884.1 - 0.067 12.9 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX73884.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX73884.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain YmgB PF10798.8 EAX73885.1 - 0.0088 15.8 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR DNA_alkylation PF08713.11 EAX73885.1 - 0.047 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme DUF2897 PF11446.8 EAX73887.1 - 5.4 7.0 8.4 0.33 10.9 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73888.1 - 3.8e-62 208.4 6.2 4.2e-62 208.3 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX73889.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX73889.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX73890.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX73890.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX73891.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX73891.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX73891.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX73891.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX73892.1 - 1.1e-113 378.7 7.7 1.2e-113 378.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73892.1 - 0.31 11.5 2.1 1.2 9.7 1.0 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX73894.1 - 6.6e-141 467.8 14.9 8.3e-141 467.5 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73894.1 - 1.2 9.7 6.6 1.9 9.0 0.5 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX73896.1 - 7.1e-30 104.3 7.1 1.2e-29 103.5 7.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral FAS_N PF17828.1 EAX73897.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73898.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX73898.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX73898.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX73899.1 - 6.5e-32 109.7 0.7 1.7e-31 108.4 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain MGC-24 PF05283.11 EAX73901.1 - 1.5 9.2 6.4 2.2 8.7 6.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR PF12789.7 EAX73902.1 - 7.9e-35 118.7 19.4 6.6e-34 115.8 15.3 4.3 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX73902.1 - 0.11 12.2 1.0 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX73903.1 - 3.4e-39 134.8 5.0 4.6e-39 134.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX73904.1 - 0.00012 22.6 0.3 0.00025 21.5 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73904.1 - 0.065 13.1 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX73904.1 - 0.12 11.9 0.4 1.8 8.1 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain T5orf172 PF10544.9 EAX73906.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX73908.1 - 3.2e-46 156.8 4.5 3.8e-46 156.6 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX73908.1 - 0.077 13.2 0.3 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide AcMNPV_Ac109 PF05054.12 EAX73908.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein KilA-N PF04383.13 EAX73910.1 - 2.8e-38 130.2 1.8 2.9e-38 130.1 0.4 1.7 2 0 0 2 2 2 1 KilA-N domain RsfS PF02410.15 EAX73910.1 - 0.038 14.4 1.6 0.094 13.2 1.2 1.7 1 1 0 1 1 1 0 Ribosomal silencing factor during starvation RRP36 PF06102.12 EAX73910.1 - 0.056 13.4 6.7 0.039 13.9 2.9 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Parathyroid PF01279.17 EAX73910.1 - 0.058 14.0 0.2 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family YmaF PF12788.7 EAX73911.1 - 0.17 12.4 1.6 2.3 8.8 1.7 2.0 1 1 0 1 1 1 0 YmaF family Trypan_PARP PF05887.11 EAX73912.1 - 0.22 11.5 12.8 0.24 11.4 12.8 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX73912.1 - 6.6 7.2 5.2 7.1 7.1 5.2 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2939 PF11159.8 EAX73914.1 - 0.016 15.6 0.5 0.017 15.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DNA_pol_B_2 PF03175.13 EAX73915.1 - 8.6e-10 38.1 3.3 4.6e-09 35.7 3.3 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX73915.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) Lac_bphage_repr PF06543.12 EAX73915.1 - 0.16 12.0 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX73915.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Mito_fiss_reg PF05308.11 EAX73919.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73919.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4106 PF13388.6 EAX73920.1 - 5.9e-257 852.6 16.2 6.7e-257 852.4 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX73920.1 - 0.00065 20.0 0.1 0.028 14.7 0.3 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX73920.1 - 0.023 14.5 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF4106 PF13388.6 EAX73921.1 - 1.1e-208 693.5 24.4 1.1e-208 693.5 24.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Ank_2 PF12796.7 EAX73922.1 - 2.2e-56 188.4 33.7 7.8e-16 58.4 2.2 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX73922.1 - 8.6e-52 171.4 19.0 1.7e-06 28.2 0.1 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 EAX73922.1 - 2e-49 165.3 17.9 9.7e-12 45.2 0.1 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX73922.1 - 4.3e-41 134.2 13.4 3.5e-05 23.9 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX73922.1 - 2.8e-40 135.9 12.5 5.9e-11 42.4 0.3 6.4 2 2 3 6 6 6 6 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX73922.1 - 0.0082 16.3 4.2 21 5.3 0.1 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX73922.1 - 0.013 15.8 1.4 2.3 8.5 0.1 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain Mago_nashi PF02792.14 EAX73922.1 - 0.087 12.9 0.2 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Mago nashi protein DUF3839 PF12943.7 EAX73923.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX73923.1 - 0.065 13.8 0.6 0.075 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX73923.1 - 0.095 12.2 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX73923.1 - 0.22 12.0 1.4 0.66 10.5 1.2 2.0 2 1 0 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX73923.1 - 0.37 11.2 2.4 1.2 9.5 1.3 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain T5orf172 PF10544.9 EAX73926.1 - 2.1e-07 31.4 0.3 3.9e-07 30.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain T5orf172 PF10544.9 EAX73928.1 - 2.4e-06 28.0 0.2 5e-06 27.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX73929.1 - 2.2e-43 146.7 0.6 5.4e-43 145.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX73929.1 - 0.02 15.5 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF3839 PF12943.7 EAX73931.1 - 3.8e-80 268.8 10.1 4.9e-80 268.5 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX73932.1 - 0.01 15.8 6.5 0.016 15.2 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SOG2 PF10428.9 EAX73932.1 - 1.2 8.2 6.2 1.3 8.1 6.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein MGC-24 PF05283.11 EAX73932.1 - 6.5 7.2 6.9 9.3 6.7 6.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR PF12789.7 EAX73933.1 - 0.00025 21.0 3.0 0.0099 15.9 0.1 2.9 3 0 0 3 3 3 2 Phage tail repeat like YmaF PF12788.7 EAX73933.1 - 0.81 10.3 5.0 9 6.9 2.0 3.0 2 1 1 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX73933.1 - 7.2 7.1 9.9 2.7 8.4 0.3 3.3 3 0 0 3 3 3 0 Phage tail fibre repeat HNH_3 PF13392.6 EAX73934.1 - 9.3e-06 25.3 0.2 1.7e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Lipid_DES PF08557.10 EAX73937.1 - 2.1 7.9 4.4 0.57 9.7 1.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) DUF3839 PF12943.7 EAX73941.1 - 1.3e-88 296.6 7.8 1.4e-88 296.4 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX73941.1 - 0.021 14.3 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX73942.1 - 3.2e-07 30.2 0.1 5e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain PapD_N PF00345.20 EAX73943.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX73943.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TMP PF05017.14 EAX73946.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX73947.1 - 1.5e-96 322.6 5.6 5.5e-96 320.7 5.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX73949.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX73949.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX73949.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX73949.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX73949.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX73949.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX73951.1 - 3e-58 195.8 5.5 3.3e-58 195.7 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX73951.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX73952.1 - 0.00014 22.3 2.6 0.0009 19.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX73952.1 - 0.077 13.6 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX73952.1 - 0.088 12.8 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX73953.1 - 7.7e-53 178.3 6.3 8.5e-53 178.1 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Annexin PF00191.20 EAX73955.1 - 0.11 12.5 0.3 0.49 10.5 0.2 2.1 1 1 1 2 2 2 0 Annexin Ank PF00023.30 EAX73956.1 - 3.3e-15 55.8 0.1 1.7e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX73956.1 - 1.4e-13 49.7 0.1 4.4e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX73956.1 - 6.4e-13 48.9 0.0 9.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX73956.1 - 2.5e-12 46.8 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX73956.1 - 2.8e-12 47.1 0.1 1e-11 45.3 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) FAS_N PF17828.1 EAX73958.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX73959.1 - 0.012 16.0 0.8 0.015 15.7 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX73959.1 - 2 7.4 4.3 2.1 7.3 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX73959.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX73959.1 - 6.1 6.8 7.6 6.8 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMP PF05017.14 EAX73960.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX73961.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX73963.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1031 PF06275.11 EAX73965.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX73965.1 - 0.14 12.3 0.3 0.61 10.2 0.2 2.0 1 1 1 2 2 2 0 Annexin DUF3839 PF12943.7 EAX73967.1 - 2e-148 492.4 15.1 2.4e-148 492.1 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX73967.1 - 0.099 12.5 1.0 0.37 10.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX73967.1 - 3.4 8.2 8.4 2 8.9 0.9 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GGDEF PF00990.21 EAX73968.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3464 PF11947.8 EAX73968.1 - 0.65 9.7 3.2 1 9.1 3.2 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX73968.1 - 9.6 6.2 6.2 19 5.2 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX73969.1 - 2.2e-63 212.5 7.2 2.4e-63 212.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4116 PF13475.6 EAX73970.1 - 0.047 13.4 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX73970.1 - 0.17 12.4 1.8 9.1 6.9 0.0 3.0 3 0 0 3 3 3 0 YmaF family adh_short_C2 PF13561.6 EAX73970.1 - 0.42 10.1 2.4 0.65 9.5 2.4 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PTR PF12789.7 EAX73971.1 - 3e-49 164.9 32.1 3.6e-33 113.4 15.7 4.5 2 2 3 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX73971.1 - 0.079 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) IKKbetaNEMObind PF12179.8 EAX73972.1 - 0.19 11.8 0.1 0.47 10.5 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Pox_A32 PF04665.12 EAX73974.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX73974.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX73974.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX73974.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX73974.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX73974.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX73974.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX73974.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX73974.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX73974.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX73974.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX73974.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Meiosis_expr PF15163.6 EAX73975.1 - 0.055 14.2 1.5 0.065 13.9 0.6 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX73975.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family DUF4108 PF13390.6 EAX73976.1 - 1.1e-63 213.4 5.9 1.3e-63 213.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX73977.1 - 2.6 8.0 4.8 5.4 7.0 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX73978.1 - 1.4e-05 25.1 1.0 1.4e-05 25.1 1.0 3.9 2 1 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX73978.1 - 0.023 14.4 0.1 0.12 12.1 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX73978.1 - 0.077 12.8 11.2 0.059 13.2 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) MeaB PF03308.16 EAX73978.1 - 0.12 11.3 2.2 0.18 10.7 2.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX73978.1 - 0.56 10.7 0.0 0.56 10.7 0.0 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3417) zf-RNPHF PF08080.12 EAX73980.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger Trypan_PARP PF05887.11 EAX73982.1 - 0.29 11.1 9.4 0.46 10.5 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX73982.1 - 2.7 5.5 13.0 3.4 5.2 13.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX73982.1 - 8.4 6.8 7.3 12 6.3 7.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX73983.1 - 5.6e-89 297.7 7.2 6.6e-89 297.5 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX73984.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX73985.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX73986.1 - 6.1e-157 520.3 13.0 7e-157 520.1 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX73986.1 - 1.1 9.8 7.1 1.3 9.5 0.5 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX73987.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX73987.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX73988.1 - 0.046 14.2 0.5 0.09 13.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX73988.1 - 0.58 10.2 3.7 14 5.8 0.2 2.7 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein KilA-N PF04383.13 EAX73989.1 - 4.6e-25 87.6 0.1 5.1e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX73990.1 - 1.2e-33 115.3 0.1 1.2e-33 115.3 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX73990.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) PTR PF12789.7 EAX73991.1 - 3.4e-21 75.1 7.3 2e-16 59.8 2.3 4.4 6 0 0 6 6 6 2 Phage tail repeat like DUF4107 PF13389.6 EAX73992.1 - 5.1e-40 137.3 3.6 5.7e-40 137.1 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX73992.1 - 0.071 13.5 0.6 0.098 13.0 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX73993.1 - 0.0037 16.9 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Tugs PF17840.1 EAX73996.1 - 0.089 13.0 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF2939 PF11159.8 EAX73999.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX73999.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74000.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX74001.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX74003.1 - 6.1e-10 38.9 0.4 1.1e-09 38.1 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain MULE PF10551.9 EAX74004.1 - 1.2e-10 41.7 1.5 2.5e-10 40.6 1.5 1.5 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX74004.1 - 0.0018 18.3 1.1 0.0059 16.7 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX74004.1 - 0.011 14.6 0.2 0.019 13.8 0.2 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF4795 PF16043.5 EAX74005.1 - 0.019 14.6 3.1 0.055 13.1 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX74005.1 - 0.038 14.1 2.5 0.038 14.1 2.5 3.2 4 1 0 4 4 4 0 Phage tail repeat like DDR PF08841.10 EAX74006.1 - 0.1 11.5 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX74006.1 - 0.13 12.8 1.4 0.18 12.2 1.4 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX74007.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pneumo_att_G PF05539.11 EAX74009.1 - 0.11 12.1 7.8 0.12 12.0 7.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_C37 PF05416.12 EAX74009.1 - 2 6.8 5.7 2.9 6.3 5.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase KilA-N PF04383.13 EAX74010.1 - 3.9e-33 113.6 0.8 7.3e-33 112.8 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74010.1 - 0.029 15.0 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX74011.1 - 1.3e-22 80.3 3.7 1.8e-22 79.9 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX74011.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX74012.1 - 8.8e-138 457.6 8.4 1e-137 457.4 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX74012.1 - 0.082 12.6 1.8 0.71 9.5 0.5 2.4 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX74012.1 - 0.16 12.3 0.9 0.47 10.8 1.1 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit KilA-N PF04383.13 EAX74013.1 - 2.4e-10 40.3 0.0 4.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain MtrG PF04210.13 EAX74013.1 - 0.19 11.6 1.0 0.27 11.1 0.2 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G EssA PF10661.9 EAX74013.1 - 0.65 9.8 4.8 1.6 8.6 4.8 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF1731 PF08338.11 EAX74015.1 - 0.16 11.9 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX74017.1 - 7.3e-07 28.9 2.6 7.3e-07 28.9 2.6 2.0 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX74017.1 - 5.7e-05 22.9 0.2 0.41 10.4 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX74017.1 - 7.7e-05 23.0 0.2 0.00062 20.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74017.1 - 0.00011 22.3 3.5 0.00028 20.9 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74017.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74017.1 - 0.0014 18.5 1.0 0.003 17.4 1.0 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74017.1 - 0.002 17.8 0.4 0.014 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74017.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74017.1 - 0.071 12.7 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX74017.1 - 0.078 13.4 0.1 0.65 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX74017.1 - 0.095 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74017.1 - 0.38 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX74019.1 - 3.4e-07 30.0 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74019.1 - 0.0059 16.3 0.1 0.0077 15.9 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74019.1 - 0.05 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74019.1 - 0.069 12.9 0.1 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74019.1 - 0.095 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74019.1 - 0.15 12.1 2.2 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX74019.1 - 0.16 12.4 2.3 0.22 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX74020.1 - 5.5e-79 265.0 9.7 7e-79 264.7 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Peptidase_M49 PF03571.15 EAX74022.1 - 5.2e-95 318.9 0.0 6.2e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 RPN6_N PF18055.1 EAX74022.1 - 0.037 14.4 0.1 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF5442 PF17514.2 EAX74022.1 - 0.048 13.9 0.6 0.93 9.7 0.2 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5442) MnmE_helical PF12631.7 EAX74022.1 - 0.052 13.7 0.3 0.1 12.7 0.3 1.5 1 1 0 1 1 1 0 MnmE helical domain Tautomerase PF01361.21 EAX74022.1 - 0.099 12.6 0.4 0.87 9.6 0.1 2.3 2 0 0 2 2 2 0 Tautomerase enzyme DUF5314 PF17241.2 EAX74022.1 - 0.11 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DUF3839 PF12943.7 EAX74023.1 - 4.2e-54 183.6 4.0 4.8e-54 183.4 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74023.1 - 0.058 12.9 0.1 0.062 12.8 0.1 1.0 1 0 0 1 1 1 0 Z1 domain Glu-tRNAGln PF02686.15 EAX74023.1 - 0.15 12.4 1.3 0.36 11.2 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4107 PF13389.6 EAX74025.1 - 5.3e-72 241.3 3.2 6.9e-72 240.9 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX74026.1 - 0.0048 17.0 0.7 0.006 16.6 0.7 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX74026.1 - 2 8.4 10.5 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PMP1_2 PF08114.11 EAX74027.1 - 0.0065 16.2 1.0 0.011 15.4 1.0 1.3 1 0 0 1 1 1 1 ATPase proteolipid family Ion_trans PF00520.31 EAX74027.1 - 0.026 13.7 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein SPC22 PF04573.12 EAX74027.1 - 0.074 12.5 1.6 0.071 12.6 0.6 1.5 1 1 1 2 2 2 0 Signal peptidase subunit FAM163 PF15069.6 EAX74027.1 - 0.097 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 FAM163 family TMEM132D_C PF15706.5 EAX74027.1 - 0.27 11.1 3.9 0.46 10.3 3.9 1.5 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term T5orf172 PF10544.9 EAX74028.1 - 0.00025 21.5 0.2 0.00066 20.2 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX74028.1 - 0.0057 15.9 0.1 0.01 15.1 0.0 1.4 2 0 0 2 2 2 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX74028.1 - 0.019 14.5 0.8 0.24 10.9 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain PTR PF12789.7 EAX74030.1 - 2.8e-22 78.5 16.3 6.6e-17 61.3 1.6 4.0 4 1 0 4 4 4 2 Phage tail repeat like RNA_lig_T4_1 PF09511.10 EAX74030.1 - 0.032 14.1 1.2 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 RNA ligase DUF4116 PF13475.6 EAX74030.1 - 0.049 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX74030.1 - 0.052 13.5 2.8 1.1 9.2 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4738 PF15889.5 EAX74030.1 - 0.095 12.5 3.7 0.19 11.6 2.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4738) DUF1493 PF07377.12 EAX74031.1 - 0.042 14.3 2.0 0.047 14.2 1.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX74033.1 - 2.2e-78 263.1 11.0 2.7e-78 262.8 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74033.1 - 0.14 12.0 1.5 0.4 10.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase LD_cluster2 PF18163.1 EAX74033.1 - 0.18 11.3 0.5 1.1 8.8 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 DUF4107 PF13389.6 EAX74034.1 - 9.5e-59 198.2 11.7 1.3e-56 191.3 11.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74034.1 - 0.08 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX74035.1 - 3.7e-59 198.8 8.6 4.1e-59 198.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VirE PF05272.11 EAX74036.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX74036.1 - 0.011 16.2 0.9 0.02 15.3 0.3 1.7 2 0 0 2 2 2 0 RNA helicase Bac_RepA_C PF18008.1 EAX74036.1 - 0.085 13.2 0.3 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain DUF1493 PF07377.12 EAX74037.1 - 0.017 15.6 0.5 0.031 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX74038.1 - 0.19 12.4 4.0 14 6.9 0.1 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX74039.1 - 4.2e-77 260.1 17.0 3.2e-60 204.5 6.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX74039.1 - 0.014 15.2 0.5 0.024 14.5 0.5 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) FTCD_C PF04961.12 EAX74039.1 - 1 9.1 6.2 43 3.8 0.0 3.4 2 2 1 3 3 3 0 Formiminotransferase-cyclodeaminase Pox_A32 PF04665.12 EAX74040.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74040.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74040.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74040.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4107 PF13389.6 EAX74041.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX74042.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4108 PF13390.6 EAX74043.1 - 2e-37 128.3 1.9 2.2e-37 128.2 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX74043.1 - 0.11 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX74045.1 - 4.7e-05 23.4 2.4 8.5e-05 22.6 2.4 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74045.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX74045.1 - 0.0004 20.7 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX74045.1 - 0.0008 19.3 0.4 0.0018 18.1 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX74045.1 - 0.0067 16.8 0.0 0.0086 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX74045.1 - 0.04 13.4 0.1 0.056 12.9 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX74045.1 - 0.066 12.9 0.1 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX74045.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX74045.1 - 0.16 12.2 4.2 4.3 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX74045.1 - 0.24 11.1 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.8 EAX74046.1 - 0.0095 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX74047.1 - 3.6e-120 399.9 7.2 4e-120 399.7 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX74048.1 - 2.9e-10 40.0 0.0 7.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX74048.1 - 0.027 13.9 0.9 0.032 13.7 0.9 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) T5orf172 PF10544.9 EAX74050.1 - 0.048 14.2 0.2 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 T5orf172 domain DUF4106 PF13388.6 EAX74051.1 - 7.5e-265 878.6 39.5 6.2e-263 872.3 39.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX74051.1 - 0.017 15.4 0.1 0.64 10.3 0.2 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated BA14K PF07886.11 EAX74051.1 - 2.9 7.9 4.0 44 4.1 0.2 3.3 1 1 2 3 3 3 0 BA14K-like protein PapD_N PF00345.20 EAX74052.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74052.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX74053.1 - 1.8e-07 30.9 0.9 2.1e-07 30.7 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74053.1 - 0.0041 16.8 0.1 0.0048 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74053.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74053.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX74054.1 - 5.3e-40 135.8 0.8 1.2e-39 134.6 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX74055.1 - 2.3e-07 31.3 0.3 4.8e-07 30.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX74055.1 - 0.13 12.9 0.4 0.36 11.5 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Pox_A32 PF04665.12 EAX74056.1 - 7.4e-07 28.9 3.1 7.4e-07 28.9 3.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74056.1 - 1e-05 25.9 0.4 7.1e-05 23.1 0.4 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74056.1 - 3.4e-05 23.6 0.7 0.55 9.9 0.0 2.9 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74056.1 - 0.00013 22.0 3.6 0.0003 20.8 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74056.1 - 0.00055 19.8 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74056.1 - 0.00097 19.0 1.2 0.002 18.0 1.2 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74056.1 - 0.0016 18.1 0.7 0.0092 15.6 0.7 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74056.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX74056.1 - 0.061 13.8 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX74056.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74056.1 - 0.083 12.3 0.1 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74056.1 - 0.28 11.4 4.9 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX74057.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74058.1 - 0.027 14.9 0.8 0.063 13.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX74059.1 - 1.1e-58 195.1 39.4 3.1e-31 107.2 14.3 4.8 2 2 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX74059.1 - 0.04 13.7 1.2 0.077 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Poxvirus_B22R_C PF13168.6 EAX74059.1 - 0.13 11.7 0.6 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal Mito_fiss_reg PF05308.11 EAX74060.1 - 0.09 12.8 0.3 0.095 12.8 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74060.1 - 0.4 10.1 1.7 0.4 10.1 1.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX74061.1 - 3.3e-42 142.9 0.3 8.7e-42 141.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX74061.1 - 0.14 10.7 0.2 0.21 10.1 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX74062.1 - 1.2e-67 227.9 3.4 1.6e-67 227.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX74064.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Spo12 PF05032.12 EAX74065.1 - 3.7 7.5 11.8 0.21 11.5 2.9 3.0 4 0 0 4 4 4 0 Spo12 family Pox_A32 PF04665.12 EAX74066.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74066.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74066.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74066.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74066.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74066.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74066.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) HTH_Tnp_4 PF13613.6 EAX74067.1 - 4.1e-05 23.2 0.2 0.00056 19.6 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 EAX74068.1 - 1.1e-19 70.7 0.0 1.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 EAX74068.1 - 0.062 13.7 0.2 0.13 12.6 0.1 1.6 2 0 0 2 2 2 0 Transposase DDE domain DUF3839 PF12943.7 EAX74073.1 - 5.9e-110 366.4 6.7 6.9e-110 366.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74073.1 - 0.043 13.3 0.4 0.061 12.8 0.4 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX74073.1 - 0.22 12.2 1.7 0.51 11.0 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX74074.1 - 1.9e-24 85.7 0.5 4.3e-24 84.5 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74074.1 - 0.0032 17.6 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) HTH_Tnp_1_2 PF13022.6 EAX74075.1 - 0.049 13.8 0.4 0.049 13.8 0.4 2.1 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase Z1 PF10593.9 EAX74075.1 - 2.7 7.4 9.9 8.5 5.8 0.2 2.2 2 0 0 2 2 2 0 Z1 domain zf-CCCH_7 PF18586.1 EAX74075.1 - 5.9 7.3 6.7 4.1 7.8 0.2 2.8 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Pox_A32 PF04665.12 EAX74076.1 - 3.6e-07 29.9 2.7 3.6e-07 29.9 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74076.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74076.1 - 0.00016 21.7 3.0 0.00037 20.5 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX74076.1 - 0.00023 20.9 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX74076.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74076.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74076.1 - 0.0013 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74076.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74076.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74076.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74076.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GPS2_interact PF15784.5 EAX74078.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74078.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain T5orf172 PF10544.9 EAX74079.1 - 9.5e-07 29.3 0.3 2.1e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74079.1 - 0.023 14.5 0.1 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain Amidase02_C PF12123.8 EAX74080.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX74081.1 - 5.7e-55 185.9 1.0 6.8e-55 185.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) SGP PF17228.2 EAX74081.1 - 0.0064 17.3 0.2 0.012 16.5 0.2 1.4 1 0 0 1 1 1 1 Sulphur globule protein DUF1476 PF07345.11 EAX74081.1 - 0.076 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX74082.1 - 4.2e-07 29.7 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX74083.1 - 0.12 13.0 4.8 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX74083.1 - 6.5 6.7 8.4 6.9 6.6 8.4 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX74084.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX74086.1 - 2.8e-05 23.7 2.7 3.6e-05 23.3 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74086.1 - 0.0036 17.0 0.2 0.005 16.5 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74086.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 L27 PF02828.16 EAX74086.1 - 0.023 14.5 0.3 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 L27 domain IstB_IS21 PF01695.17 EAX74086.1 - 0.035 13.8 0.3 0.15 11.7 0.2 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74086.1 - 0.076 12.8 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74086.1 - 0.12 12.4 2.3 1 9.4 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74086.1 - 0.48 10.6 8.8 4.8 7.4 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX74089.1 - 5.1e-10 38.8 1.5 9.9e-10 37.9 1.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX74091.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74091.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74091.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74091.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74091.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74091.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74091.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74091.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74091.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX74091.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX74091.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74091.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Trypan_PARP PF05887.11 EAX74095.1 - 0.015 15.3 10.2 0.017 15.1 10.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX74096.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) FAS_N PF17828.1 EAX74097.1 - 0.017 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX74097.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX74098.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74098.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX74099.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX74099.1 - 0.078 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX74099.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) JMY PF15871.5 EAX74100.1 - 0.045 13.1 0.4 0.075 12.3 0.4 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3447 PF11929.8 EAX74101.1 - 5.9e-30 103.1 9.4 5.9e-30 103.1 9.4 3.6 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX74101.1 - 7.7e-20 71.0 5.4 1.3e-10 41.6 0.3 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX74101.1 - 1.4e-16 60.8 10.3 3.5e-10 40.3 2.9 4.2 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX74101.1 - 1.4e-14 53.7 8.6 9.2e-05 22.7 0.3 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX74101.1 - 6.8e-14 50.6 4.2 0.00024 21.3 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX74101.1 - 2.2e-12 46.9 3.4 5e-07 29.9 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Cnd1 PF12717.7 EAX74101.1 - 0.014 15.5 0.4 0.042 13.9 0.2 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1048 PF06304.11 EAX74101.1 - 0.034 14.6 0.5 0.35 11.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) Amidase02_C PF12123.8 EAX74102.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX74103.1 - 2.9e-63 212.1 5.8 3.2e-63 211.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74104.1 - 0.38 10.7 3.6 0.74 9.7 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX74104.1 - 0.44 10.9 3.0 0.56 10.6 3.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3839 PF12943.7 EAX74105.1 - 1.4e-102 342.3 6.7 1.5e-102 342.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) EpuA PF11772.8 EAX74106.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pox_A32 PF04665.12 EAX74108.1 - 1.1e-07 31.6 3.1 1.3e-07 31.3 0.5 2.0 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74108.1 - 0.061 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74108.1 - 0.096 12.5 0.2 0.16 11.8 0.2 1.4 1 1 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74108.1 - 0.21 11.7 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMP PF05017.14 EAX74112.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74113.1 - 0.087 13.3 0.5 0.19 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX74114.1 - 9.6e-45 151.0 0.2 9.6e-45 151.0 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74114.1 - 0.037 14.2 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX74115.1 - 7.2e-05 22.4 0.4 8.2e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74115.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pox_A32 PF04665.12 EAX74116.1 - 2.5e-07 30.4 2.5 3.3e-07 30.0 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74116.1 - 0.0045 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74116.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74116.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74116.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74116.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74116.1 - 0.57 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Nrf1_DNA-bind PF10491.9 EAX74117.1 - 0.0068 16.1 0.4 0.0075 16.0 0.4 1.1 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2939 PF11159.8 EAX74117.1 - 0.022 15.1 0.2 0.026 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX74118.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX74118.1 - 0.047 13.7 0.9 0.068 13.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Ank_4 PF13637.6 EAX74120.1 - 1.8e-11 44.3 1.3 4.4e-06 27.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX74120.1 - 2.5e-11 44.0 0.3 2.8e-11 43.8 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX74120.1 - 1.4e-07 31.6 4.4 9.1e-05 22.7 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX74120.1 - 6.6e-07 29.5 0.2 1e-06 28.9 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX74120.1 - 7.5e-07 29.0 0.1 0.0001 22.4 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat DUF1440 PF07274.12 EAX74121.1 - 0.022 15.1 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) TMEM154 PF15102.6 EAX74121.1 - 0.067 13.1 2.6 0.098 12.6 2.6 1.3 1 1 0 1 1 1 0 TMEM154 protein family ORC6 PF05460.13 EAX74121.1 - 0.22 10.7 7.9 0.24 10.6 7.9 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AvrE_T3Es PF11725.8 EAX74121.1 - 0.41 7.8 2.2 0.46 7.6 2.2 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) Shisa PF13908.6 EAX74121.1 - 8.8 6.5 8.4 0.83 9.9 2.7 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Pox_A32 PF04665.12 EAX74122.1 - 3.2e-07 30.1 0.9 1.7e-06 27.7 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74122.1 - 0.063 12.9 0.1 0.77 9.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74122.1 - 0.065 13.1 0.3 0.12 12.2 0.3 1.5 1 1 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74122.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GPS2_interact PF15784.5 EAX74125.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74125.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain RFX_DNA_binding PF02257.15 EAX74126.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX74126.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX74126.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF5623 PF18536.1 EAX74127.1 - 0.075 13.3 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX74127.1 - 0.18 11.7 5.6 0.15 12.0 2.9 2.1 2 1 0 2 2 2 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX74128.1 - 1.5e-11 43.9 0.3 3.3e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX74128.1 - 0.083 12.2 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX74130.1 - 1.8e-26 93.1 4.2 2.1e-26 92.9 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RecO_C PF02565.15 EAX74130.1 - 0.15 11.9 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Recombination protein O C terminal Amidase02_C PF12123.8 EAX74131.1 - 0.0036 16.9 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF2294 PF10057.9 EAX74132.1 - 0.0022 18.1 10.6 2.3 8.4 0.3 3.8 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2294) DUF1935 PF09149.10 EAX74132.1 - 0.057 13.8 12.1 0.078 13.4 2.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1935) Fucose_iso_C PF02952.17 EAX74132.1 - 0.14 11.9 3.2 0.42 10.3 0.2 2.4 1 1 2 3 3 3 0 L-fucose isomerase, C-terminal domain Porin_10 PF14121.6 EAX74132.1 - 0.21 10.1 8.0 0.75 8.3 1.0 1.9 1 1 1 2 2 2 0 Putative porin FAM219A PF15260.6 EAX74132.1 - 0.25 11.7 15.4 4.1 7.8 1.5 3.2 1 1 2 3 3 3 0 Protein family FAM219A PS-DH PF14765.6 EAX74132.1 - 0.27 10.4 17.5 2.4 7.3 6.5 2.1 1 1 1 2 2 2 0 Polyketide synthase dehydratase MlaD PF02470.20 EAX74132.1 - 0.59 10.5 12.0 2.6 8.4 0.7 3.7 1 1 3 4 4 4 0 MlaD protein AlkA_N PF06029.11 EAX74132.1 - 0.63 10.3 3.2 12 6.2 1.6 2.5 1 1 2 3 3 3 0 AlkA N-terminal domain DUF749 PF05370.11 EAX74132.1 - 0.75 9.9 7.8 5.3 7.2 1.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF749) Tail_tube PF10618.9 EAX74132.1 - 0.99 9.3 9.3 1.7 8.6 3.3 2.2 1 1 1 2 2 2 0 Phage tail tube protein DUF2584 PF10763.9 EAX74132.1 - 3.4 7.9 9.1 18 5.6 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2584) Golgin_A5 PF09787.9 EAX74132.1 - 5.7 6.3 25.9 2.8 7.3 24.1 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2031 PF09592.10 EAX74132.1 - 6.5 6.2 15.5 5.4 6.5 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) DUF4884 PF16225.5 EAX74132.1 - 6.7 6.9 10.2 84 3.4 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4884) DsbC PF11412.8 EAX74132.1 - 7.8 6.6 11.5 51 3.9 0.1 4.0 4 0 0 4 4 4 0 Disulphide bond corrector protein DsbC KilA-N PF04383.13 EAX74133.1 - 1e-33 115.5 1.1 2.2e-33 114.4 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74133.1 - 0.039 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX74133.1 - 0.15 10.6 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Spo0A_C PF08769.11 EAX74138.1 - 0.052 13.6 0.4 0.094 12.8 0.4 1.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF1128 PF06569.11 EAX74139.1 - 0.33 11.0 3.5 4.5 7.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) TMP PF05017.14 EAX74141.1 - 0.041 14.4 5.9 4.4 8.4 0.4 3.3 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX74142.1 - 8.8e-22 77.6 5.0 1.1e-21 77.2 5.0 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.7 EAX74144.1 - 6.6e-46 154.8 17.9 1.5e-14 54.3 0.5 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX74144.1 - 1.6e-32 111.4 5.0 4.7e-12 46.2 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX74144.1 - 9.9e-26 89.0 6.3 9.5e-08 32.2 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX74144.1 - 1.6e-25 86.3 3.9 3.7e-07 29.9 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX74144.1 - 7.8e-21 73.9 3.4 1.9e-10 40.8 0.2 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) PrmC_N PF17827.1 EAX74144.1 - 0.0046 17.5 0.8 14 6.4 0.1 3.7 3 1 0 3 3 3 1 PrmC N-terminal domain DUF3677 PF12432.8 EAX74144.1 - 0.013 15.8 0.0 1.1e+02 3.3 0.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3677) DUF348 PF03990.14 EAX74144.1 - 0.027 14.2 1.5 51 3.7 0.0 4.1 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain Arg_repressor PF01316.21 EAX74144.1 - 0.029 14.1 0.1 29 4.5 0.0 3.7 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain DUF3718 PF12514.8 EAX74144.1 - 0.08 13.1 2.4 16 5.8 0.1 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3718) DUF3492 PF11997.8 EAX74144.1 - 0.097 12.4 0.1 26 4.4 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3492) RGP PF03214.13 EAX74144.1 - 0.13 11.4 0.0 14 4.7 0.0 2.9 1 1 3 4 4 4 0 Reversibly glycosylated polypeptide Stap_Strp_toxin PF01123.20 EAX74144.1 - 0.18 12.6 1.0 43 5.1 0.0 3.2 1 1 2 3 3 3 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3839 PF12943.7 EAX74145.1 - 2.9e-120 400.2 5.2 3.3e-120 400.0 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74145.1 - 0.24 11.9 1.5 1.1 9.8 0.5 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX74147.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74147.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX74148.1 - 2.4e-119 397.2 11.0 3e-119 396.9 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74148.1 - 0.051 13.4 1.0 0.17 11.7 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX74148.1 - 0.1 13.1 1.9 4.4 7.8 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX74148.1 - 0.19 12.3 1.0 0.33 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX74149.1 - 4.3e-16 58.8 0.8 5.1e-16 58.6 0.8 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX74149.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX74150.1 - 3.5e-08 33.2 1.9 4.3e-08 32.9 1.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74150.1 - 0.0031 17.2 0.2 0.0033 17.1 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX74150.1 - 0.0094 15.9 0.8 0.62 10.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX74150.1 - 0.043 13.6 0.1 0.087 12.6 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein RnlB_antitoxin PF15933.5 EAX74150.1 - 0.078 13.3 0.4 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA Trypan_PARP PF05887.11 EAX74151.1 - 0.12 12.3 7.1 0.19 11.7 7.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX74152.1 - 0.018 15.4 0.4 0.027 14.9 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74152.1 - 2.5 8.1 5.5 2.6 8.0 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX74154.1 - 6.4e-08 32.4 1.3 7.8e-08 32.1 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74154.1 - 0.0038 16.9 0.1 0.0038 16.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74154.1 - 0.055 13.2 0.0 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74154.1 - 0.063 13.3 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) UCH PF00443.29 EAX74155.1 - 9.8e-23 81.0 0.0 4.6e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX74155.1 - 2.1e-06 27.6 0.4 3.4e-05 23.6 0.1 2.0 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Vps39_2 PF10367.9 EAX74155.1 - 0.077 13.5 0.1 0.96 9.9 0.1 2.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Transposase_1 PF01359.18 EAX74156.1 - 0.00012 21.9 0.2 0.00024 20.9 0.1 1.7 1 1 1 2 2 2 1 Transposase (partial DDE domain) Lar_N PF09861.9 EAX74156.1 - 0.002 17.3 0.1 0.0022 17.2 0.1 1.0 1 0 0 1 1 1 1 Lactate racemase N-terminal domain DDE_3 PF13358.6 EAX74156.1 - 0.055 13.2 0.2 0.061 13.1 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease TMP PF05017.14 EAX74157.1 - 0.037 14.6 4.0 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74158.1 - 0.024 15.1 0.4 0.055 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) CREPT PF16566.5 EAX74159.1 - 0.032 14.4 0.3 0.076 13.2 0.3 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX74159.1 - 0.72 10.0 5.2 0.33 11.1 1.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pox_D5 PF03288.16 EAX74163.1 - 6.2e-06 26.6 2.1 3.2e-05 24.3 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74163.1 - 0.032 14.8 0.1 0.064 13.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74163.1 - 0.091 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain MetallophosC PF16370.5 EAX74164.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Dimer_Tnp_hAT PF05699.14 EAX74165.1 - 0.073 12.9 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PTR PF12789.7 EAX74166.1 - 1.5e-34 117.8 25.9 1.9e-32 111.1 13.7 6.3 4 2 3 7 7 7 3 Phage tail repeat like Transposase_24 PF03004.14 EAX74166.1 - 5.7 7.0 16.2 0.3 11.2 1.1 3.5 2 1 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) DUF2939 PF11159.8 EAX74167.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74167.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX74167.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein PapD_N PF00345.20 EAX74168.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain FucT_N PF18025.1 EAX74168.1 - 0.39 11.2 5.1 0.52 10.8 0.3 2.9 2 1 1 3 3 3 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain HD_3 PF13023.6 EAX74169.1 - 0.034 14.1 0.3 0.045 13.7 0.3 1.1 1 0 0 1 1 1 0 HD domain Amidase02_C PF12123.8 EAX74170.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX74171.1 - 1.4e-40 139.1 3.6 1.5e-40 139.0 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74171.1 - 0.065 13.6 0.7 0.084 13.3 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX74172.1 - 1.8e-124 414.0 8.5 2e-124 413.8 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74172.1 - 0.35 11.4 2.3 1.3 9.5 1.1 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX74173.1 - 3.2e-61 205.5 8.5 3.5e-61 205.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX74173.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX74174.1 - 9.4e-05 22.8 3.5 0.00054 20.4 3.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX74174.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX74174.1 - 0.073 13.7 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain KilA-N PF04383.13 EAX74176.1 - 6.6e-23 80.7 0.7 1.4e-22 79.6 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX74177.1 - 2.1e-06 28.2 0.1 4.2e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX74178.1 - 6.4e-08 32.4 0.9 7.6e-08 32.1 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74178.1 - 0.0047 16.6 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74178.1 - 0.048 13.4 0.1 0.085 12.6 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74178.1 - 0.064 13.2 0.4 0.59 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX74179.1 - 3e-28 98.9 7.6 4.2e-28 98.4 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX74179.1 - 0.052 12.7 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II PapD_N PF00345.20 EAX74181.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74181.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4106 PF13388.6 EAX74182.1 - 1.1e-20 74.3 5.1 1.6e-20 73.7 4.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) LZ3wCH PF18517.1 EAX74182.1 - 0.15 12.1 0.9 13 5.9 0.1 2.8 2 0 0 2 2 2 0 Leucine zipper with capping helix domain FapA PF03961.13 EAX74182.1 - 0.75 8.3 3.3 1.1 7.8 3.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A RSS_P20 PF11757.8 EAX74183.1 - 0.18 12.3 4.7 4.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF3839 PF12943.7 EAX74184.1 - 1.9e-25 89.7 4.4 2.8e-25 89.2 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_D5 PF03288.16 EAX74185.1 - 6.1e-05 23.4 3.7 0.0004 20.8 3.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74185.1 - 0.068 13.8 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74185.1 - 0.08 12.9 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX74186.1 - 1.4e-62 209.8 8.3 1.6e-62 209.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RGS12_us1 PF16613.5 EAX74187.1 - 0.18 12.1 4.0 0.24 11.7 4.0 1.2 1 0 0 1 1 1 0 Unstructured region of RGS12 DUF3447 PF11929.8 EAX74188.1 - 1.6e-34 117.7 6.0 1.6e-34 117.7 6.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX74188.1 - 2.4e-05 24.8 0.1 0.00029 21.3 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX74190.1 - 9.5e-13 48.5 3.0 3.2e-12 46.9 0.9 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX74190.1 - 1.8e-10 41.1 1.9 4.5e-06 27.1 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX74190.1 - 1.9e-10 40.0 0.2 0.1 13.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX74190.1 - 2.9e-10 40.2 1.3 3.7e-06 27.1 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX74190.1 - 4.7e-05 23.6 0.2 0.94 10.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Trypan_PARP PF05887.11 EAX74191.1 - 0.019 14.9 8.2 0.024 14.6 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74191.1 - 6.1 7.3 6.1 7.4 7.0 6.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX74192.1 - 0.023 15.1 0.6 0.03 14.8 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAX74192.1 - 0.038 14.4 2.2 0.038 14.4 2.2 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DNA_pol_B_2 PF03175.13 EAX74193.1 - 9.9e-16 57.6 0.5 1.2e-15 57.4 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ly49 PF08391.10 EAX74195.1 - 0.13 12.6 2.0 0.16 12.3 2.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX74195.1 - 0.55 10.2 3.0 0.8 9.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74196.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74197.1 - 2.5e-05 24.7 2.5 0.00015 22.2 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX74198.1 - 3.2e-79 265.8 11.6 4.2e-79 265.4 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX74198.1 - 0.07 12.7 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 KilA-N PF04383.13 EAX74199.1 - 1.2e-25 89.6 0.2 3.3e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74199.1 - 0.086 13.5 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_D5 PF03288.16 EAX74200.1 - 3e-05 24.4 2.7 0.00018 21.9 2.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX74201.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) SH3BGR PF04908.15 EAX74202.1 - 0.2 11.8 3.3 0.23 11.6 3.1 1.3 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ly49 PF08391.10 EAX74202.1 - 0.21 11.9 2.1 0.27 11.6 2.1 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX74202.1 - 0.54 10.2 3.0 0.77 9.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) JMY PF15871.5 EAX74203.1 - 0.0013 18.1 0.6 0.0016 17.8 0.6 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX74203.1 - 0.1 12.7 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DUF4107 PF13389.6 EAX74204.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX74205.1 - 6.7e-97 325.4 4.4 7.8e-97 325.1 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) HRM PF02793.22 EAX74207.1 - 0.15 12.4 2.4 0.66 10.3 2.4 2.2 1 1 0 1 1 1 0 Hormone receptor domain Pox_A32 PF04665.12 EAX74209.1 - 2.3e-07 30.5 0.6 1.3e-06 28.1 0.0 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein PBAN PF05874.11 EAX74209.1 - 0.031 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) TK PF00265.18 EAX74209.1 - 0.043 13.7 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Zot PF05707.12 EAX74209.1 - 0.055 13.1 0.1 1.2 8.8 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2897 PF11446.8 EAX74210.1 - 0.7 9.8 3.2 1.5 8.7 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX74210.1 - 1.4 9.3 4.6 1.9 8.9 4.2 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4108 PF13390.6 EAX74211.1 - 3.9e-62 208.4 6.1 4.3e-62 208.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_5 PF13306.6 EAX74212.1 - 3.4e-44 149.9 20.4 1.6e-26 92.7 14.0 2.9 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX74212.1 - 3.8e-10 39.4 0.0 0.1 12.4 0.0 5.0 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EAX74212.1 - 0.00084 19.7 0.3 2.7 8.6 0.0 4.2 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF3839 PF12943.7 EAX74213.1 - 6.8e-118 392.4 10.1 8.3e-118 392.1 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74213.1 - 0.063 13.1 0.8 0.2 11.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX74214.1 - 2.9e-08 33.5 0.8 3.5e-08 33.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74214.1 - 0.0035 17.0 0.1 0.0036 17.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74214.1 - 0.071 12.8 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74214.1 - 0.081 12.9 0.4 0.65 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX74215.1 - 2e-25 89.7 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX74216.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74216.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74216.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74216.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX74217.1 - 4.8e-07 30.3 0.5 9.6e-07 29.3 0.5 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74218.1 - 2.9e-41 139.8 0.2 2.9e-41 139.8 0.2 2.0 2 1 1 3 3 3 1 KilA-N domain DUF2608 PF11019.8 EAX74218.1 - 0.017 14.6 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Acyl_transf_2 PF02273.15 EAX74218.1 - 0.055 12.7 0.2 0.34 10.1 0.1 1.9 1 1 1 2 2 2 0 Acyl transferase ABC1 PF03109.16 EAX74218.1 - 0.18 12.0 0.1 0.18 12.0 0.1 1.8 2 1 1 3 3 3 0 ABC1 family Amidase02_C PF12123.8 EAX74221.1 - 0.0037 16.9 0.1 0.0097 15.6 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX74222.1 - 6.3e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX74222.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX74222.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_A32 PF04665.12 EAX74223.1 - 1e-06 28.4 2.7 1e-06 28.4 2.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX74223.1 - 3.6e-05 23.6 0.3 0.35 10.6 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX74223.1 - 5.2e-05 23.5 0.2 0.00034 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74223.1 - 0.00043 20.3 3.6 0.00099 19.1 3.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74223.1 - 0.00074 19.3 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74223.1 - 0.0023 17.8 1.0 0.0045 16.8 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74223.1 - 0.006 16.2 2.7 0.016 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74223.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX74223.1 - 0.074 13.5 0.0 0.66 10.4 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX74223.1 - 0.098 12.2 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX74223.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX74223.1 - 0.12 12.4 0.7 1.8 8.7 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX74223.1 - 0.56 10.9 11.3 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX74223.1 - 0.66 10.3 4.6 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX74225.1 - 1.5e-157 522.3 15.1 1.8e-157 522.0 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74225.1 - 0.068 13.6 1.9 0.15 12.5 0.3 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX74225.1 - 0.1 12.1 0.1 0.35 10.4 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX74225.1 - 0.94 10.0 8.1 2.1 8.9 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX74226.1 - 3.1e-41 139.7 0.7 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX74226.1 - 0.33 9.5 0.2 0.48 8.9 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) LOH1CR12 PF10158.9 EAX74226.1 - 0.42 10.6 3.1 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX74227.1 - 1.2e-07 31.4 0.4 1.3e-07 31.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74227.1 - 0.0051 15.7 0.0 0.0064 15.4 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX74227.1 - 0.01 15.5 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX74227.1 - 0.049 13.6 0.4 0.47 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX74227.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX74228.1 - 7.1e-81 271.2 10.4 9.1e-81 270.9 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74228.1 - 0.051 14.1 0.3 0.088 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX74229.1 - 4.5e-80 268.6 11.6 5.8e-80 268.2 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74229.1 - 0.037 14.5 0.5 0.044 14.2 0.5 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX74229.1 - 0.064 12.8 0.7 0.24 10.9 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX74229.1 - 0.093 13.3 0.8 0.15 12.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX74231.1 - 2e-64 215.8 6.1 2.2e-64 215.7 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX74232.1 - 0.083 12.8 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX74233.1 - 3e-72 242.1 3.6 3.9e-72 241.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74233.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Peptidase_M8 PF01457.16 EAX74234.1 - 7.8e-10 38.1 0.0 1.1e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 Leishmanolysin Reprolysin_3 PF13582.6 EAX74234.1 - 0.097 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Porin_4 PF13609.6 EAX74235.1 - 7.3e-08 32.5 1.8 1.2e-07 31.8 1.8 1.3 1 0 0 1 1 1 1 Gram-negative porin DcpS_C PF11969.8 EAX74235.1 - 0.024 15.1 2.5 4.3 7.8 0.0 3.0 2 1 1 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding Sec_GG PF07549.14 EAX74235.1 - 9.9 5.8 8.0 80 2.9 0.2 3.6 3 0 0 3 3 3 0 SecD/SecF GG Motif Pox_A32 PF04665.12 EAX74238.1 - 8.2e-09 35.3 0.1 1.2e-08 34.7 0.1 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74238.1 - 0.00026 20.7 0.0 0.00034 20.3 0.0 1.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX74238.1 - 0.071 13.0 1.6 0.1 12.4 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 PTR PF12789.7 EAX74239.1 - 7.3e-84 275.8 59.7 1.1e-31 108.7 14.5 6.0 2 2 3 5 5 5 4 Phage tail repeat like DUF4116 PF13475.6 EAX74239.1 - 0.031 14.0 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) P22_AR_C PF10548.9 EAX74240.1 - 0.094 12.9 0.2 26 5.1 0.1 2.6 2 0 0 2 2 2 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX74240.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin TMP PF05017.14 EAX74241.1 - 0.14 12.8 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX74244.1 - 0.0055 17.1 0.4 0.0067 16.8 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74244.1 - 1.1 9.3 4.8 1.2 9.2 4.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74245.1 - 0.014 15.4 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX74247.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74247.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX74247.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX74247.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74248.1 - 0.0099 15.9 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Tmemb_9 PF05434.11 EAX74249.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 DUF3467 PF11950.8 EAX74250.1 - 0.13 12.5 0.6 2.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DUF3574 PF12098.8 EAX74250.1 - 0.17 11.7 0.9 0.25 11.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) DUF1493 PF07377.12 EAX74251.1 - 0.02 15.4 1.4 0.028 14.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX74252.1 - 6.6e-24 83.7 7.1 6.6e-24 83.7 7.1 3.9 4 1 1 5 5 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX74252.1 - 0.015 15.0 0.1 0.057 13.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX74252.1 - 0.43 10.5 6.8 1.6 8.7 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF4106 PF13388.6 EAX74253.1 - 1.1e-262 871.5 17.4 1.3e-262 871.3 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX74253.1 - 0.028 14.2 0.2 0.066 13.0 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) KAR PF15222.6 EAX74253.1 - 0.028 14.7 0.1 0.71 10.2 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated HD-ZIP_N PF04618.12 EAX74254.1 - 0.018 15.6 0.1 0.028 14.9 0.1 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF4106 PF13388.6 EAX74256.1 - 1.3e-249 828.5 37.2 6.1e-151 503.4 13.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX74256.1 - 0.031 14.6 0.1 0.62 10.4 0.2 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated DIT1_PvcA PF05141.12 EAX74256.1 - 1.8 7.9 9.5 2.9 7.3 9.5 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4108 PF13390.6 EAX74258.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74259.1 - 3.9e-156 517.7 13.5 4.8e-156 517.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74259.1 - 0.027 14.9 1.5 0.16 12.4 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX74259.1 - 0.39 11.2 6.8 2.2 8.8 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX74259.1 - 6.3 7.2 7.5 12 6.2 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal Nmad5 PF18757.1 EAX74260.1 - 0.00014 22.1 4.6 22 5.2 0.0 5.2 1 1 5 6 6 6 2 Nucleotide modification associated domain 5 DUF481 PF04338.12 EAX74260.1 - 0.0094 16.0 12.7 2 8.4 2.3 4.0 1 1 2 3 3 3 3 Protein of unknown function, DUF481 CTD PF12815.7 EAX74260.1 - 0.018 15.6 9.5 1.2 9.8 1.2 3.7 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF2897 PF11446.8 EAX74261.1 - 2 8.4 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74262.1 - 3.4e-64 215.1 5.5 3.8e-64 214.9 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DDR PF08841.10 EAX74263.1 - 0.085 11.8 0.1 0.088 11.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX74263.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX74264.1 - 0.021 14.8 7.6 0.032 14.2 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74264.1 - 2 8.9 5.8 2.9 8.3 5.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapD_N PF00345.20 EAX74266.1 - 0.022 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain NAD_Gly3P_dh_N PF01210.23 EAX74267.1 - 4.9e-24 85.1 0.0 5.4e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EAX74267.1 - 0.0008 19.9 0.1 0.014 16.0 0.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Herpes_VP19C PF03327.14 EAX74268.1 - 0.13 11.7 0.3 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Caskin-tail PF16632.5 EAX74268.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin DUF1493 PF07377.12 EAX74269.1 - 0.028 14.9 0.8 0.085 13.3 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX74270.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX74271.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74271.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74271.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74271.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74271.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74271.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) HD_3 PF13023.6 EAX74272.1 - 0.062 13.2 0.9 0.082 12.8 0.9 1.1 1 0 0 1 1 1 0 HD domain DDE_Tnp_ISL3 PF01610.17 EAX74273.1 - 9e-06 25.6 0.1 1.3e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Transposase Adeno_E1B_55K PF01696.17 EAX74273.1 - 0.034 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Pox_A32 PF04665.12 EAX74276.1 - 4.5e-05 23.0 0.4 5.4e-05 22.8 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein PTR PF12789.7 EAX74277.1 - 2.9e-46 155.4 32.0 1.5e-30 105.1 12.4 6.2 5 2 2 7 7 7 3 Phage tail repeat like Phage_TAC_2 PF06894.11 EAX74278.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G ECH_1 PF00378.20 EAX74278.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DDE_Tnp_ISL3 PF01610.17 EAX74279.1 - 0.033 13.9 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 Transposase DUF3839 PF12943.7 EAX74280.1 - 8.8e-53 179.2 3.9 1e-52 179.1 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Gly-zipper_Omp PF13488.6 EAX74282.1 - 0.0098 15.9 9.0 0.0098 15.9 9.0 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX74282.1 - 0.32 11.3 4.8 0.49 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74282.1 - 1.3 9.2 5.8 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif T5orf172 PF10544.9 EAX74283.1 - 0.00087 19.8 0.1 0.0024 18.4 0.1 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX74283.1 - 0.078 12.5 0.3 0.72 9.3 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX74284.1 - 2.7e-56 190.7 4.0 3e-56 190.6 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX74285.1 - 5.9e-07 29.2 2.4 5.9e-07 29.2 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74285.1 - 0.00024 21.4 0.3 0.0018 18.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74285.1 - 0.00027 20.7 0.5 0.43 10.3 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74285.1 - 0.00038 20.5 4.1 0.00091 19.3 4.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74285.1 - 0.0009 19.1 0.1 0.0016 18.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX74285.1 - 0.0034 17.1 0.5 0.012 15.2 0.2 1.9 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74285.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX74285.1 - 0.088 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_11 PF13086.6 EAX74285.1 - 0.13 12.0 1.2 0.29 10.9 1.2 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX74285.1 - 0.21 11.8 4.1 10 6.5 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_14 PF13173.6 EAX74285.1 - 0.44 10.6 3.2 5.7 7.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain PadR PF03551.14 EAX74288.1 - 0.13 12.3 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX74290.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX74291.1 - 1.2e-38 131.0 28.7 1.2e-32 111.7 13.6 3.8 4 1 1 5 5 5 2 Phage tail repeat like Gly-zipper_Omp PF13488.6 EAX74294.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX74294.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX74294.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX74294.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74294.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Amidase02_C PF12123.8 EAX74296.1 - 0.0035 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX74297.1 - 3.6e-44 150.8 1.0 4e-44 150.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74297.1 - 0.081 13.3 0.8 0.095 13.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX74298.1 - 3.1e-74 249.5 5.2 3.6e-74 249.3 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74298.1 - 0.054 13.0 0.1 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 Z1 domain Glu-tRNAGln PF02686.15 EAX74298.1 - 0.088 13.1 1.2 0.21 11.9 1.2 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit TMP PF05017.14 EAX74299.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74300.1 - 0.039 14.4 0.3 0.079 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX74301.1 - 2.2e-05 24.4 0.6 2.2e-05 24.4 0.6 4.2 2 1 2 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX74301.1 - 0.014 15.2 0.1 0.064 13.0 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX74301.1 - 0.052 12.5 2.0 0.078 11.9 2.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX74301.1 - 0.11 13.0 0.1 0.11 13.0 0.1 3.3 2 1 2 5 5 5 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX74301.1 - 0.41 10.4 11.0 0.87 9.3 11.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX74301.1 - 0.61 9.6 23.5 0.18 11.4 7.9 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX74302.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74303.1 - 0.41 10.5 2.8 0.76 9.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX74305.1 - 0.0011 18.6 0.1 0.0032 17.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX74306.1 - 9.6e-269 891.4 20.0 1.1e-268 891.3 20.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX74306.1 - 0.00054 20.2 0.2 0.026 14.8 0.3 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX74306.1 - 0.046 13.5 0.2 0.09 12.6 0.2 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NPA PF16469.5 EAX74307.1 - 0.078 13.6 0.3 18 5.9 0.0 2.2 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 KilA-N PF04383.13 EAX74308.1 - 2.7e-13 49.8 1.0 5.6e-13 48.7 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74308.1 - 0.02 15.5 0.0 0.041 14.5 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family DUF4107 PF13389.6 EAX74310.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX74313.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74313.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74313.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74313.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MULE PF10551.9 EAX74314.1 - 7.1e-11 42.4 0.2 1.3e-10 41.6 0.2 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF3839 PF12943.7 EAX74316.1 - 2.2e-39 135.3 4.4 3.2e-39 134.8 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX74316.1 - 0.078 13.3 0.7 0.26 11.6 0.1 2.0 1 1 1 2 2 2 0 PRD domain PapD_N PF00345.20 EAX74318.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Trypan_PARP PF05887.11 EAX74320.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX74321.1 - 0.006 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX74321.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX74323.1 - 3.3e-22 78.4 0.1 5.8e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX74323.1 - 0.018 15.0 0.4 0.095 12.7 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin EF-hand_1 PF00036.32 EAX74323.1 - 0.17 11.5 1.4 14 5.5 0.0 2.8 2 0 0 2 2 2 0 EF hand Pox_A32 PF04665.12 EAX74325.1 - 4.2e-08 32.9 0.5 4.7e-08 32.8 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74325.1 - 0.0048 16.5 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX74325.1 - 0.073 13.0 0.3 0.59 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX74325.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4108 PF13390.6 EAX74326.1 - 3.6e-62 208.5 7.7 4e-62 208.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX74327.1 - 0.028 14.8 0.3 0.038 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX74327.1 - 2.7 8.7 6.8 6.3 7.5 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX74328.1 - 0.0065 16.5 0.2 0.0088 16.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX74329.1 - 0.0037 16.9 0.1 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase EpuA PF11772.8 EAX74331.1 - 0.018 14.7 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DUF1947 PF09183.10 EAX74331.1 - 0.11 12.9 0.9 0.27 11.5 0.1 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) PTR PF12789.7 EAX74332.1 - 4.8e-22 77.8 8.2 2.4e-16 59.5 2.0 4.1 6 0 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX74332.1 - 0.05 13.3 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX74333.1 - 8.3e-75 251.4 7.8 1e-74 251.0 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ANAPC4_WD40 PF12894.7 EAX74334.1 - 0.00016 21.9 0.1 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_B_2 PF03175.13 EAX74335.1 - 3.6e-17 62.4 3.3 6.8e-17 61.5 3.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX74335.1 - 0.053 12.8 0.3 0.083 12.2 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX74336.1 - 2.1e-05 25.0 0.9 0.00032 21.2 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX74336.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX74336.1 - 0.032 13.8 0.9 0.42 10.1 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4106 PF13388.6 EAX74338.1 - 2.6e-175 583.7 67.0 3.3e-110 369.2 10.9 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) PT PF04886.12 EAX74338.1 - 0.00083 18.8 39.8 0.00083 18.8 39.8 2.7 1 1 1 2 2 2 1 PT repeat DDE_Tnp_4 PF13359.6 EAX74339.1 - 7.9e-16 58.1 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.29 EAX74339.1 - 7e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX74339.1 - 0.00051 19.7 0.0 0.0014 18.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.11 EAX74339.1 - 0.044 13.5 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Renin_r PF07850.14 EAX74340.1 - 0.032 14.8 0.0 36 5.1 0.0 3.2 1 1 2 3 3 3 0 Renin receptor-like protein PH_TFIIH PF08567.11 EAX74340.1 - 0.15 12.4 1.7 64 4.0 0.0 3.7 2 1 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain Pox_D5 PF03288.16 EAX74343.1 - 8.1e-05 23.0 2.2 0.00055 20.4 2.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX74344.1 - 7.9e-60 200.9 7.7 8.8e-60 200.8 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX74345.1 - 2e-60 202.8 6.4 2.3e-60 202.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX74347.1 - 8.8e-05 23.0 0.1 0.00021 21.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX74347.1 - 0.0092 15.5 0.3 0.055 13.0 0.1 1.9 2 0 0 2 2 2 1 Legume lectin domain PTR PF12789.7 EAX74349.1 - 2e-16 59.8 2.5 2e-16 59.8 2.5 3.7 2 1 1 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX74349.1 - 0.031 13.9 8.5 0.042 13.4 5.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX74349.1 - 0.045 14.3 0.0 0.085 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Amidase02_C PF12123.8 EAX74350.1 - 0.0038 16.9 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX74351.1 - 2.3e-64 218.2 1.5 2.3e-64 218.2 1.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) DUF885 PF05960.11 EAX74351.1 - 0.00031 20.5 1.9 0.00036 20.3 1.9 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) FapA PF03961.13 EAX74351.1 - 0.57 8.7 4.3 0.7 8.4 4.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4472 PF14739.6 EAX74351.1 - 0.85 10.4 10.1 1.5 9.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4446 PF14584.6 EAX74351.1 - 4 7.4 4.9 0.86 9.6 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) La PF05383.17 EAX74352.1 - 0.033 14.2 0.1 0.085 12.9 0.1 1.7 1 0 0 1 1 1 0 La domain DUF4378 PF14309.6 EAX74352.1 - 0.06 13.7 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) RST PF12174.8 EAX74352.1 - 0.083 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF2897 PF11446.8 EAX74353.1 - 0.093 12.6 2.1 0.18 11.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74354.1 - 1.1e-59 200.5 7.9 1.2e-59 200.4 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74355.1 - 2.1e-05 24.9 2.2 9.7e-05 22.8 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74355.1 - 0.049 14.3 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74355.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX74356.1 - 3.4e-154 511.3 14.2 3.9e-154 511.1 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74356.1 - 0.07 13.6 1.3 0.43 11.0 0.2 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX74356.1 - 0.095 13.3 4.3 1.2 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX74356.1 - 0.18 12.1 2.1 0.36 11.2 1.1 2.1 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX74356.1 - 0.36 11.1 4.7 3.7 7.9 0.0 3.3 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX74356.1 - 0.56 10.7 6.6 4.3 7.9 0.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX74356.1 - 1.7 9.3 4.6 1.3 9.7 0.1 3.0 2 2 2 4 4 4 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX74357.1 - 6.9e-35 120.6 2.7 7.6e-35 120.5 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74357.1 - 0.062 13.7 0.2 0.098 13.0 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX74358.1 - 0.0091 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF5623 PF18536.1 EAX74359.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX74359.1 - 0.18 11.7 5.6 0.15 12.0 2.9 2.1 2 1 0 2 2 2 0 Spo12 family TPR_MLP1_2 PF07926.12 EAX74360.1 - 0.046 13.8 0.2 0.058 13.5 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX74360.1 - 0.088 12.6 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX74360.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Aa_trans PF01490.18 EAX74361.1 - 2.5e-14 52.8 16.6 3e-14 52.6 16.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PSI_8 PF00796.18 EAX74361.1 - 0.04 13.8 4.6 0.04 13.8 4.6 2.6 4 0 0 4 4 4 0 Photosystem I reaction centre subunit VIII TatC PF00902.18 EAX74361.1 - 0.37 10.6 13.4 0.79 9.5 13.4 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF3522 PF12036.8 EAX74361.1 - 2.2 8.5 12.1 24 5.1 12.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) DUF4106 PF13388.6 EAX74362.1 - 7e-258 855.7 20.8 8.5e-258 855.4 20.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX74362.1 - 0.00084 19.6 0.2 0.03 14.6 0.3 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX74362.1 - 0.0075 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) Peptidase_S28 PF05577.12 EAX74362.1 - 0.94 8.2 4.9 1.4 7.6 4.9 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DegS PF05384.11 EAX74362.1 - 1.2 8.6 7.2 0.24 10.9 2.0 2.1 2 0 0 2 2 2 0 Sensor protein DegS PTR PF12789.7 EAX74363.1 - 3.6e-28 97.4 25.2 7.6e-24 83.5 6.5 4.7 4 1 0 4 4 4 2 Phage tail repeat like DUF3417 PF11897.8 EAX74363.1 - 0.14 12.7 3.6 0.16 12.4 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX74363.1 - 1.5 8.5 13.3 0.073 12.9 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX74363.1 - 1.9 8.0 26.3 1.5e+04 -4.7 26.3 3.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Gly-zipper_Omp PF13488.6 EAX74365.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX74365.1 - 0.23 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74365.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX74366.1 - 2e-29 101.4 22.4 6.8e-21 74.1 7.7 4.4 4 3 1 5 5 5 2 Phage tail repeat like Phage_fiber PF03335.13 EAX74366.1 - 9.4 6.7 14.3 6.2 7.3 0.2 3.7 4 0 0 4 4 4 0 Phage tail fibre repeat T5orf172 PF10544.9 EAX74368.1 - 1.9e-06 28.4 0.2 3.6e-06 27.4 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74369.1 - 5.3e-32 110.0 0.4 1.2e-31 108.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX74370.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74370.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX74370.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX74370.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX74370.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PTR PF12789.7 EAX74371.1 - 1.5e-27 95.4 13.8 1.5e-27 95.4 13.8 3.8 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX74371.1 - 0.086 12.6 1.0 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX74371.1 - 8.2 6.4 10.0 1.7 8.6 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF240) Pox_A32 PF04665.12 EAX74372.1 - 6.5e-07 29.1 2.7 6.5e-07 29.1 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX74372.1 - 3.1e-05 23.8 0.2 0.36 10.5 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX74372.1 - 7.5e-05 23.0 0.2 0.00047 20.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74372.1 - 9.5e-05 22.5 3.4 0.00017 21.6 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74372.1 - 0.00057 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX74372.1 - 0.0028 17.3 0.6 0.016 14.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX74372.1 - 0.0029 17.5 1.0 0.0054 16.6 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX74372.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX74372.1 - 0.06 12.9 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX74372.1 - 0.064 12.8 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX74372.1 - 0.083 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX74372.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74372.1 - 0.11 12.9 0.1 0.61 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX74372.1 - 0.21 11.8 4.3 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1031 PF06275.11 EAX74373.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX74373.1 - 0.16 12.0 0.3 0.82 9.8 0.2 2.1 1 1 1 2 2 2 0 Annexin ARA70 PF12489.8 EAX74374.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DNA_pol_B_2 PF03175.13 EAX74375.1 - 8.8e-30 104.0 5.2 1.6e-29 103.1 5.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Retinin_C PF04527.12 EAX74376.1 - 0.08 13.2 7.6 6.5 7.1 0.2 3.4 3 0 0 3 3 3 0 Drosophila Retinin like protein Trypan_PARP PF05887.11 EAX74380.1 - 0.059 13.3 9.5 0.089 12.8 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74380.1 - 4.1 7.9 6.0 5.8 7.4 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX74381.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74381.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX74382.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74382.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4795 PF16043.5 EAX74383.1 - 0.0088 15.7 5.0 1 8.9 0.3 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) ESAG1 PF03238.13 EAX74383.1 - 0.053 13.0 4.1 0.43 10.0 0.4 3.0 1 1 2 3 3 3 0 ESAG protein GST_C PF00043.25 EAX74383.1 - 0.087 13.0 1.0 2.3 8.5 0.0 3.1 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain GP3_package PF16677.5 EAX74383.1 - 1.9 8.7 4.3 37 4.5 4.3 2.9 1 1 0 1 1 1 0 DNA-packaging protein gp3 DUF3839 PF12943.7 EAX74386.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX74387.1 - 1.8e-156 518.8 10.6 2.2e-156 518.5 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX74388.1 - 6.4e-07 29.1 2.6 6.4e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74388.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74388.1 - 6.9e-05 22.6 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74388.1 - 0.00012 22.2 2.9 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74388.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74388.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74388.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74388.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74388.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX74388.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX74388.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74388.1 - 0.4 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PI_PP_C PF18365.1 EAX74389.1 - 0.12 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Pox_A32 PF04665.12 EAX74392.1 - 1.3e-06 28.0 2.3 1.3e-06 28.0 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74392.1 - 3.6e-05 24.1 0.2 0.00025 21.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74392.1 - 4e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74392.1 - 0.00013 22.0 3.3 0.00027 21.0 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74392.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74392.1 - 0.0014 18.5 0.6 0.0028 17.5 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74392.1 - 0.0017 18.0 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74392.1 - 0.0099 16.2 0.0 0.022 15.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain Epimerase_2 PF02350.19 EAX74392.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase AAA_25 PF13481.6 EAX74392.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74392.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74392.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX74392.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4795 PF16043.5 EAX74394.1 - 0.011 15.3 1.8 0.026 14.1 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX74394.1 - 0.026 14.6 1.8 0.026 14.6 1.8 3.3 4 1 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX74394.1 - 8.7 6.8 15.3 3.7 8.0 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX74395.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74395.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74395.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74395.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX74396.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX74397.1 - 3.5e-98 321.6 72.4 9.2e-33 112.1 15.2 5.4 2 2 4 6 6 6 4 Phage tail repeat like HS1_rep PF02218.15 EAX74397.1 - 0.00022 21.5 0.0 62 4.0 0.0 5.4 6 0 0 6 6 6 0 Repeat in HS1/Cortactin HigB_toxin PF09907.9 EAX74397.1 - 0.013 15.7 0.1 8.1 6.8 0.0 3.1 1 1 2 3 3 3 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system PBP5_C PF07943.13 EAX74397.1 - 0.031 14.5 0.1 0.24 11.6 0.0 2.5 2 1 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain PH_TFIIH PF08567.11 EAX74397.1 - 4 7.8 9.7 45 4.5 0.2 4.7 1 1 5 6 6 6 0 TFIIH p62 subunit, N-terminal domain DUF4108 PF13390.6 EAX74398.1 - 6.4e-65 217.4 6.7 7.2e-65 217.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX74399.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX74399.1 - 8.2 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX74401.1 - 3.4e-08 33.3 0.1 7.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX74401.1 - 0.2 11.1 0.3 0.37 10.2 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX74402.1 - 8.8e-121 401.9 11.6 1.1e-120 401.6 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74402.1 - 0.028 14.9 1.3 5.3 7.6 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX74402.1 - 0.19 11.6 1.8 0.51 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX74403.1 - 3.5e-11 43.0 5.3 3.5e-11 43.0 5.3 4.4 4 1 0 4 4 4 1 Phage tail repeat like Phage_fiber PF03335.13 EAX74403.1 - 5.2 7.5 19.1 9.1 6.8 0.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX74404.1 - 2.3e-75 253.2 8.2 3e-75 252.8 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX74404.1 - 0.096 12.2 0.5 0.28 10.7 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX74405.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74405.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74405.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74405.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PapD_N PF00345.20 EAX74407.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74407.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX74408.1 - 0.0038 17.7 0.3 0.0044 17.5 0.3 1.2 1 0 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX74409.1 - 1.3e-37 129.4 3.2 1.5e-37 129.2 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX74411.1 - 3.3e-41 139.6 0.2 3.3e-41 139.6 0.2 2.0 2 1 1 3 3 3 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX74411.1 - 0.063 12.5 0.2 0.37 10.0 0.1 1.9 1 1 1 2 2 2 0 Acyl transferase ABC1 PF03109.16 EAX74411.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.8 2 1 2 4 4 4 0 ABC1 family T5orf172 PF10544.9 EAX74412.1 - 4.8e-07 30.3 0.5 9.6e-07 29.3 0.5 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF2897 PF11446.8 EAX74414.1 - 0.095 12.6 3.0 0.17 11.8 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74415.1 - 5.4e-63 211.2 5.8 6e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74416.1 - 1.7e-05 25.2 2.4 9.4e-05 22.8 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74416.1 - 0.04 14.5 0.1 0.084 13.5 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74416.1 - 0.14 12.2 0.8 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX74417.1 - 4.2e-79 265.4 9.8 5.4e-79 265.1 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX74417.1 - 0.44 10.6 2.7 2.1 8.5 1.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pox_A32 PF04665.12 EAX74418.1 - 5.7e-08 32.5 1.0 7e-08 32.2 1.0 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74418.1 - 0.0048 16.6 0.1 0.0052 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74418.1 - 0.065 13.0 0.0 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74418.1 - 0.067 13.1 0.4 0.61 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF563 PF04577.14 EAX74419.1 - 3.3e-31 109.0 0.6 4.6e-31 108.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pox_A32 PF04665.12 EAX74421.1 - 4.9e-07 29.5 0.1 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein PBAN PF05874.11 EAX74421.1 - 0.084 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) DUF948 PF06103.11 EAX74422.1 - 0.27 11.5 9.3 0.37 11.1 9.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pox_A32 PF04665.12 EAX74426.1 - 6.5e-08 32.3 0.9 7.8e-08 32.1 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74426.1 - 0.0048 16.6 0.1 0.0052 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74426.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.5 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74426.1 - 0.072 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_Ag35 PF03286.14 EAX74427.1 - 1.7 8.4 2.8 2.2 8.0 0.5 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3839 PF12943.7 EAX74429.1 - 2.7e-53 180.9 3.5 3.1e-53 180.7 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74429.1 - 0.096 12.2 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Z1 domain Glu-tRNAGln PF02686.15 EAX74429.1 - 0.18 12.1 1.3 0.41 11.0 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Amidase02_C PF12123.8 EAX74430.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX74431.1 - 3.6e-44 150.8 1.0 4e-44 150.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74431.1 - 0.081 13.3 0.8 0.095 13.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4106 PF13388.6 EAX74432.1 - 1.2e-267 887.8 18.4 1.4e-267 887.6 18.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX74432.1 - 0.017 14.9 0.2 0.038 13.8 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) KAR PF15222.6 EAX74432.1 - 0.032 14.5 0.1 0.74 10.2 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated FAS_N PF17828.1 EAX74434.1 - 0.0041 17.1 0.3 0.0054 16.7 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HI0933_like PF03486.14 EAX74434.1 - 0.19 10.4 1.0 0.24 10.1 1.0 1.0 1 0 0 1 1 1 0 HI0933-like protein DUF2939 PF11159.8 EAX74435.1 - 0.0093 16.4 0.4 0.011 16.1 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74435.1 - 4.1 7.4 5.7 4.3 7.3 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Glyco_hydro_2_C PF02836.17 EAX74438.1 - 0.074 12.1 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DDR PF08841.10 EAX74439.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX74440.1 - 0.02 14.9 9.5 0.022 14.8 9.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74440.1 - 0.62 10.5 5.7 0.72 10.3 5.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX74441.1 - 7.2e-43 145.0 0.6 1.4e-42 144.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74441.1 - 0.0056 17.3 0.0 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family KilA-N PF04383.13 EAX74442.1 - 1.3e-17 63.6 0.1 1.6e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain FAS_N PF17828.1 EAX74445.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX74446.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74446.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX74446.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX74446.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Mito_fiss_reg PF05308.11 EAX74447.1 - 0.063 13.4 0.3 0.068 13.3 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74447.1 - 0.34 10.3 1.6 0.34 10.4 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX74448.1 - 4.3e-155 514.2 12.1 5.1e-155 514.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74448.1 - 0.28 11.7 5.1 4.1 7.9 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX74449.1 - 5e-63 211.3 6.0 5.6e-63 211.2 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74450.1 - 2.1e-56 191.1 4.0 2.4e-56 190.9 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74450.1 - 0.04 13.4 0.2 0.044 13.3 0.2 1.0 1 0 0 1 1 1 0 Z1 domain DUF3781 PF12636.7 EAX74451.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX74452.1 - 3.3e-27 95.5 6.0 4.7e-27 95.0 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX74452.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DNA_pol_B_2 PF03175.13 EAX74453.1 - 5.7e-23 81.5 8.2 2.1e-22 79.6 3.6 1.9 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX74454.1 - 5.9e-36 122.7 0.7 5.9e-36 122.7 0.7 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74454.1 - 0.027 14.7 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KilA-N PF04383.13 EAX74455.1 - 6.1e-44 148.4 0.8 1.1e-43 147.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74455.1 - 0.048 14.3 0.3 0.19 12.3 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family DUF3447 PF11929.8 EAX74456.1 - 0.0016 18.4 0.3 0.0032 17.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) DUF3781 PF12636.7 EAX74458.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX74459.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX74460.1 - 0.017 15.1 7.6 0.021 14.8 7.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX74461.1 - 6.1e-63 211.0 5.4 6.7e-63 210.9 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX74463.1 - 9.4e-23 80.0 9.6 3.1e-16 59.2 2.5 5.7 6 2 0 6 6 6 2 Phage tail repeat like DUF3391 PF11871.8 EAX74463.1 - 3.3 8.2 7.3 1.8 9.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) KilA-N PF04383.13 EAX74464.1 - 1.4e-25 89.3 1.3 2.1e-25 88.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX74464.1 - 0.05 14.3 1.4 13 6.6 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DDR PF08841.10 EAX74466.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX74466.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain ARA70 PF12489.8 EAX74470.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator Gly-zipper_Omp PF13488.6 EAX74472.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX74472.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74472.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DNA_pol_B_2 PF03175.13 EAX74473.1 - 1.7e-10 40.4 2.5 8.6e-10 38.1 2.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX74473.1 - 0.045 12.5 1.7 4.4 5.9 1.8 3.1 2 1 0 2 2 2 0 DNA polymerase family B Lac_bphage_repr PF06543.12 EAX74473.1 - 0.14 12.2 0.0 0.93 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX74473.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) BHD_1 PF10403.9 EAX74475.1 - 0.052 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 T5orf172 PF10544.9 EAX74477.1 - 1.2e-06 28.9 0.1 2.4e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74478.1 - 2.4e-40 136.9 1.0 3.6e-40 136.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74478.1 - 0.012 16.2 0.6 0.029 15.0 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family DUF4352 PF11611.8 EAX74480.1 - 0.019 15.3 1.1 0.031 14.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Pox_A32 PF04665.12 EAX74481.1 - 1.6e-07 31.0 0.6 1.2e-06 28.1 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74481.1 - 0.054 13.1 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74481.1 - 0.099 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74481.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX74482.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74482.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74482.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74482.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) HNH_3 PF13392.6 EAX74484.1 - 3.4e-08 33.1 0.3 6.1e-08 32.3 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3839 PF12943.7 EAX74486.1 - 1.1e-156 519.4 13.9 1.4e-156 519.1 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX74486.1 - 0.11 12.9 0.2 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX74486.1 - 1.3 9.5 7.7 1.5 9.3 0.5 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX74487.1 - 1.8e-63 214.2 4.2 2.4e-63 213.8 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX74487.1 - 0.055 12.6 0.1 0.076 12.2 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX74487.1 - 0.15 12.6 0.4 1 9.8 0.1 2.2 3 0 0 3 3 3 0 Cell division protein ZapB PTR PF12789.7 EAX74488.1 - 1.7e-73 242.6 47.6 4.1e-31 106.8 13.3 5.0 2 2 2 4 4 4 3 Phage tail repeat like AviRa PF11599.8 EAX74488.1 - 0.17 11.4 5.2 0.56 9.6 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF3839 PF12943.7 EAX74489.1 - 1.4e-134 447.1 12.4 1.6e-134 446.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74489.1 - 0.04 14.4 2.0 1.2 9.7 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX74490.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74490.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74490.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74490.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX74492.1 - 0.38 10.7 2.8 0.76 9.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX74494.1 - 1.2e-06 29.0 0.2 2.5e-06 27.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74495.1 - 1.1e-40 138.0 0.1 1.5e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX74496.1 - 7.7e-78 261.3 10.0 1.1e-77 260.8 10.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74496.1 - 0.068 13.7 0.3 0.12 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 EAX74496.1 - 0.076 13.3 0.4 0.14 12.4 0.4 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Gly-zipper_Omp PF13488.6 EAX74497.1 - 0.00069 19.6 8.3 0.0012 18.8 8.3 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX74497.1 - 0.035 13.4 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase PsbY PF06298.11 EAX74497.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) DUF1269 PF06897.12 EAX74497.1 - 0.1 12.9 4.6 0.16 12.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74497.1 - 0.83 9.8 4.9 1.4 9.0 4.9 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif SLBB PF10531.9 EAX74498.1 - 1e-05 25.3 0.0 1.9e+02 2.0 0.0 6.7 7 0 0 7 7 7 0 SLBB domain DUF5439 PF17507.2 EAX74498.1 - 1.3e-05 25.3 0.0 1.1e+02 3.2 0.0 6.0 7 0 0 7 7 7 0 Family of unknown function (DUF5439) Glyco_hydro_68 PF02435.16 EAX74498.1 - 1.5e-05 24.0 0.0 15 4.3 0.0 5.0 1 1 5 6 6 6 5 Levansucrase/Invertase IKKbetaNEMObind PF12179.8 EAX74498.1 - 0.00022 21.2 0.0 3.5e+02 1.3 0.0 6.4 7 0 0 7 7 7 0 I-kappa-kinase-beta NEMO binding domain EP400_N PF15790.5 EAX74498.1 - 0.0006 18.8 0.0 29 3.3 0.0 5.2 1 1 5 6 6 6 0 E1A-binding protein p400, N-terminal zf-C2H2_3rep PF18868.1 EAX74498.1 - 0.026 15.2 0.0 50 4.6 0.0 4.7 6 1 0 7 7 7 0 Zinc finger C2H2-type, 3 repeats Tht1 PF04163.12 EAX74498.1 - 3.1 6.4 5.3 9.5 4.9 0.2 3.4 1 1 5 6 6 6 0 Tht1-like nuclear fusion protein FAS_N PF17828.1 EAX74499.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX74499.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX74500.1 - 0.027 14.9 0.4 0.036 14.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74500.1 - 1 8.3 2.5 1.1 8.2 2.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX74500.1 - 1.1 9.3 5.5 1.2 9.1 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX74501.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74501.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX74503.1 - 1.3e-63 213.2 6.5 1.4e-63 213.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX74505.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74505.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX74508.1 - 3.3e-17 62.8 0.3 3.6e-17 62.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX74509.1 - 0.0098 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX74510.1 - 7e-44 148.3 0.7 1.5e-43 147.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74510.1 - 0.019 15.1 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) LOH1CR12 PF10158.9 EAX74510.1 - 1.1 9.3 4.3 1.4 8.9 0.3 2.3 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX74511.1 - 2.1e-07 31.5 0.4 4.1e-07 30.5 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX74511.1 - 0.13 13.0 0.5 0.34 11.6 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX74513.1 - 9.5e-25 86.6 1.2 1.8e-24 85.7 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain RRP36 PF06102.12 EAX74513.1 - 0.08 12.9 7.3 0.12 12.3 7.3 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF2897 PF11446.8 EAX74515.1 - 0.8 9.6 3.2 1.4 8.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74516.1 - 4.1e-60 201.9 7.2 4.5e-60 201.7 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74517.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74517.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74517.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain Trypan_PARP PF05887.11 EAX74518.1 - 0.13 12.2 11.8 0.14 12.1 11.8 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74518.1 - 1.1 9.8 5.4 1.2 9.6 5.4 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX74519.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX74519.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GPS2_interact PF15784.5 EAX74521.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74521.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3447 PF11929.8 EAX74523.1 - 9.6e-27 92.8 1.4 9.6e-27 92.8 1.4 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX74523.1 - 2.6e-24 85.3 4.5 1.1e-10 41.8 0.0 5.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX74523.1 - 2.9e-22 79.0 3.7 4.1e-13 49.7 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX74523.1 - 7.6e-18 64.1 5.1 2.2e-05 24.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX74523.1 - 9.7e-18 64.0 0.3 6.5e-12 45.4 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX74523.1 - 2e-15 55.3 2.8 3.8e-06 26.8 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat DUF4107 PF13389.6 EAX74524.1 - 1.2e-71 240.2 4.4 1.4e-71 239.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ComA PF02679.15 EAX74525.1 - 0.056 12.9 0.7 0.067 12.6 0.7 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX74525.1 - 0.11 11.9 0.5 0.21 11.0 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX74526.1 - 1.2e-150 499.7 11.9 1.4e-150 499.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74526.1 - 0.039 14.4 1.1 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX74526.1 - 0.13 12.1 1.1 0.48 10.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX74526.1 - 6.2 7.4 7.2 5.1 7.6 0.6 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX74527.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74527.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74527.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74527.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX74528.1 - 2.2e-24 85.4 1.7 2.7e-24 85.2 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74528.1 - 0.0042 17.7 0.1 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX74530.1 - 8.5e-21 74.3 4.4 1.2e-20 73.8 4.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Flavodoxin_2 PF02525.17 EAX74532.1 - 3.3e-37 128.1 0.0 4.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX74532.1 - 0.0031 17.3 0.0 0.058 13.1 0.0 2.2 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Pox_A32 PF04665.12 EAX74534.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74534.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74534.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74534.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX74535.1 - 2.2e-16 59.7 2.1 2.4e-16 59.6 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74535.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX74535.1 - 0.081 11.5 0.1 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX74536.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74536.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74536.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74536.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74536.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX74536.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX74537.1 - 5.2e-10 39.2 0.1 6e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX74538.1 - 4.7e-44 148.8 0.3 1.1e-43 147.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74538.1 - 0.02 15.5 0.1 0.068 13.8 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family Spo0A_C PF08769.11 EAX74539.1 - 0.049 13.7 0.2 0.1 12.7 0.2 1.4 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Ank_2 PF12796.7 EAX74540.1 - 3.4e-68 226.3 24.3 7.7e-15 55.2 0.4 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX74540.1 - 8.5e-55 180.9 16.3 3.8e-08 33.4 0.1 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAX74540.1 - 4.2e-52 173.5 18.7 8.2e-11 41.9 0.2 4.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX74540.1 - 1.1e-49 166.2 13.4 2e-12 47.4 0.2 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX74540.1 - 9.5e-45 145.4 9.0 9.2e-06 25.6 0.0 6.0 6 0 0 6 6 6 6 Ankyrin repeat DUF3718 PF12514.8 EAX74540.1 - 4.7e-08 33.1 3.0 14 5.9 0.0 6.0 1 1 5 6 6 6 0 Protein of unknown function (DUF3718) B5 PF03484.15 EAX74540.1 - 6.9e-06 26.3 0.1 48 4.4 0.0 5.1 1 1 4 5 5 5 0 tRNA synthetase B5 domain DUF1965 PF09248.10 EAX74540.1 - 1.2e-05 25.0 0.1 46 3.9 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1965) MTHFR PF02219.17 EAX74540.1 - 0.00012 21.6 2.0 42 3.3 0.0 5.1 6 0 0 6 6 6 0 Methylenetetrahydrofolate reductase Imm53 PF15580.6 EAX74540.1 - 0.00023 20.8 15.0 3.1 7.6 1.1 5.1 1 1 4 5 5 5 4 Immunity protein 53 DUF503 PF04456.12 EAX74540.1 - 0.00024 20.9 5.9 32 4.5 0.0 5.3 1 1 5 6 6 6 0 Protein of unknown function (DUF503) B12-binding PF02310.19 EAX74540.1 - 0.0052 16.8 0.1 14 5.7 0.0 4.1 1 1 2 4 4 4 0 B12 binding domain GspH PF12019.8 EAX74540.1 - 0.0058 17.0 1.2 7 7.1 1.2 3.7 1 1 0 1 1 1 1 Type II transport protein GspH AbrB_C PF18277.1 EAX74540.1 - 0.027 14.1 5.1 2e+02 1.8 0.0 5.7 6 0 0 6 6 6 0 AbrB C-terminal domain PH_8 PF15409.6 EAX74540.1 - 0.18 12.1 8.7 1.4e+02 2.9 0.0 5.4 1 1 5 6 6 6 0 Pleckstrin homology domain Sec31 PF11549.8 EAX74540.1 - 8.9 6.3 23.2 44 4.1 0.3 5.7 6 0 0 6 6 6 0 Protein transport protein SEC31 Pox_A32 PF04665.12 EAX74543.1 - 2e-07 30.7 0.5 1.7e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74543.1 - 0.058 13.0 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74543.1 - 0.098 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74543.1 - 0.2 11.8 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX74546.1 - 1.7e-25 89.9 4.1 2.4e-25 89.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Kelch_1 PF01344.25 EAX74549.1 - 0.00011 21.7 0.2 62 3.3 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Phage_P2_GpE PF06528.12 EAX74549.1 - 0.00015 21.2 0.3 1.2e+02 2.4 0.0 5.6 6 0 0 6 6 6 0 Phage P2 GpE DUF5438 PF17506.2 EAX74549.1 - 0.011 16.1 14.3 10 6.5 0.8 5.4 1 1 4 5 5 5 0 Family of unknown function (DUF5438) Phage_P2_GpE PF06528.12 EAX74550.1 - 3.2e-05 23.4 0.1 1.1e+02 2.5 0.0 6.4 7 0 0 7 7 7 0 Phage P2 GpE Kelch_1 PF01344.25 EAX74550.1 - 0.092 12.3 0.1 88 2.8 0.0 3.5 3 1 0 3 3 3 0 Kelch motif DUF5438 PF17506.2 EAX74550.1 - 0.13 12.6 15.1 24 5.3 0.3 5.4 1 1 3 5 5 5 0 Family of unknown function (DUF5438) Imm41 PF15592.6 EAX74550.1 - 0.66 10.3 9.0 4.5 7.6 3.4 2.2 1 1 1 2 2 2 0 Immunity protein 41 S_100 PF01023.19 EAX74550.1 - 6.6 6.5 9.7 2.4e+02 1.5 0.0 5.7 7 0 0 7 7 7 0 S-100/ICaBP type calcium binding domain PTR PF12789.7 EAX74553.1 - 3.2e-22 78.3 7.7 3.2e-22 78.3 7.7 3.3 2 1 2 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX74553.1 - 0.011 15.4 0.1 0.046 13.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX74555.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Chal_sti_synt_N PF00195.19 EAX74559.1 - 0.071 12.5 0.2 0.13 11.6 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX74559.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX74560.1 - 4e-157 520.9 13.5 4.7e-157 520.7 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74560.1 - 0.17 11.8 1.0 0.5 10.2 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX74561.1 - 1.4e-156 519.1 15.6 1.7e-156 518.8 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX74561.1 - 0.11 12.9 0.3 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX74561.1 - 1.8 9.1 7.4 2.3 8.8 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDR PF08841.10 EAX74562.1 - 0.14 11.1 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4795 PF16043.5 EAX74563.1 - 2.6e-05 23.9 17.1 0.055 13.1 1.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) SEP PF08059.13 EAX74563.1 - 0.64 10.6 3.6 12 6.6 1.0 2.7 1 1 1 2 2 2 0 SEP domain Phage_fiber PF03335.13 EAX74563.1 - 2 8.8 9.8 0.47 10.7 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat GPS2_interact PF15784.5 EAX74565.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74565.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Mito_fiss_reg PF05308.11 EAX74566.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74566.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX74571.1 - 5e-13 48.9 0.4 5e-13 48.9 0.4 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74571.1 - 0.01 16.5 0.1 0.022 15.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Gly-zipper_Omp PF13488.6 EAX74573.1 - 0.0045 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX74573.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74573.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Fumble PF03630.14 EAX74576.1 - 1.8e-47 162.1 0.2 2.8e-47 161.5 0.2 1.3 1 1 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 EAX74576.1 - 0.015 14.8 0.1 0.022 14.3 0.1 1.2 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 EAX74576.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family DUF3839 PF12943.7 EAX74577.1 - 3.3e-115 383.6 7.8 3.8e-115 383.4 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX74577.1 - 0.26 11.6 1.3 0.61 10.4 1.4 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4108 PF13390.6 EAX74579.1 - 3.2e-62 208.7 6.0 3.6e-62 208.5 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX74581.1 - 5.5e-37 126.0 0.9 9.2e-37 125.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74581.1 - 0.0052 17.4 0.5 0.012 16.2 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family FLYWCH PF04500.16 EAX74582.1 - 0.036 14.2 3.9 0.061 13.4 3.9 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX74582.1 - 0.058 14.1 1.0 0.15 12.8 1.0 1.6 1 1 0 1 1 1 0 FAR1 DNA-binding domain ABC2_membrane_3 PF12698.7 EAX74584.1 - 4.8e-05 22.6 0.8 6e-05 22.3 0.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4366 PF14283.6 EAX74584.1 - 0.0034 17.4 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 EAX74584.1 - 0.004 17.1 1.3 0.0053 16.7 1.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAX74584.1 - 0.0042 16.5 0.2 0.0047 16.4 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RIFIN PF02009.16 EAX74584.1 - 0.014 15.3 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX74584.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) OppC_N PF12911.7 EAX74584.1 - 0.027 14.5 0.9 0.051 13.5 0.9 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4448 PF14610.6 EAX74584.1 - 0.028 14.2 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FeoB_associated PF12669.7 EAX74584.1 - 0.037 14.4 2.1 0.061 13.7 2.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CD34_antigen PF06365.12 EAX74584.1 - 0.057 13.0 0.3 0.08 12.5 0.3 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 EAX74584.1 - 0.099 12.7 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gemini_mov PF01708.16 EAX74584.1 - 1.7 8.4 4.1 3.5 7.5 1.5 2.0 1 1 1 2 2 2 0 Geminivirus putative movement protein KilA-N PF04383.13 EAX74585.1 - 1.1e-41 141.1 0.5 2.4e-41 140.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74585.1 - 0.065 13.9 0.1 0.17 12.5 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX74586.1 - 1.5e-06 28.7 0.2 2.9e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Dynein_light PF01221.18 EAX74587.1 - 2.9e-21 75.6 0.1 3.2e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Hormone_1 PF00103.20 EAX74587.1 - 0.046 13.5 0.1 0.048 13.4 0.1 1.1 1 0 0 1 1 1 0 Somatotropin hormone family Dehydrin PF00257.19 EAX74588.1 - 0.036 14.6 1.7 0.04 14.5 1.7 1.2 1 0 0 1 1 1 0 Dehydrin Presenilin PF01080.17 EAX74588.1 - 2.7 6.7 3.6 2.9 6.6 3.6 1.0 1 0 0 1 1 1 0 Presenilin KilA-N PF04383.13 EAX74589.1 - 1e-39 134.9 0.6 1e-39 134.9 0.6 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74589.1 - 0.013 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX74590.1 - 1.1e-06 29.1 0.2 2e-06 28.3 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX74591.1 - 5.5e-21 74.4 6.5 2.7e-16 59.4 1.7 5.5 5 2 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX74591.1 - 0.017 14.8 1.8 0.017 14.8 1.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DDE_1 PF03184.19 EAX74592.1 - 2.1e-13 50.3 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Spo0A_C PF08769.11 EAX74592.1 - 0.13 12.4 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF4108 PF13390.6 EAX74596.1 - 2.3e-57 192.9 4.2 2.5e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74597.1 - 0.1 12.5 3.0 0.2 11.6 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX74598.1 - 7.6e-30 102.8 12.3 7.6e-30 102.8 12.3 3.2 2 1 0 2 2 2 1 Phage tail repeat like Imm32 PF15566.6 EAX74598.1 - 0.39 10.5 4.7 3 7.7 0.4 2.9 1 1 1 2 2 2 0 Immunity protein 32 Phage_fiber PF03335.13 EAX74598.1 - 1.2 9.5 12.5 6.9 7.1 0.2 3.6 4 0 0 4 4 4 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX74599.1 - 0.019 15.4 1.3 0.027 14.9 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX74600.1 - 3.8e-07 29.8 2.1 5.7e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74600.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74600.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74600.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74600.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX74600.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX74600.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74600.1 - 0.59 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PadR PF03551.14 EAX74602.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX74603.1 - 5e-10 38.9 1.9 7.3e-10 38.3 1.0 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Amidase02_C PF12123.8 EAX74604.1 - 0.0091 15.7 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX74605.1 - 6.2e-122 405.7 12.5 7.6e-122 405.4 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74605.1 - 0.0089 16.5 2.1 0.69 10.4 0.0 2.8 2 1 0 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF29 PF01724.16 EAX74605.1 - 0.061 13.6 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX74605.1 - 0.11 12.3 1.6 0.3 10.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX74606.1 - 2.3e-33 115.7 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX74608.1 - 0.025 15.1 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX74608.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Parathyroid PF01279.17 EAX74609.1 - 0.038 14.6 0.1 0.08 13.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family FAS_N PF17828.1 EAX74610.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX74611.1 - 0.0058 17.0 0.7 0.0074 16.7 0.4 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74611.1 - 1.4 7.8 4.0 1.4 7.9 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX74611.1 - 4.8 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX74611.1 - 6.8 6.7 7.9 7.5 6.6 7.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX74612.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX74612.1 - 0.053 13.5 0.2 0.065 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PTR PF12789.7 EAX74614.1 - 2e-50 168.7 34.8 2.8e-33 113.8 16.9 4.7 3 2 2 5 5 5 2 Phage tail repeat like DUF4108 PF13390.6 EAX74615.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74616.1 - 3.8e-05 24.1 2.5 0.00018 21.9 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74616.1 - 0.025 15.2 0.1 0.055 14.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX74616.1 - 0.067 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX74618.1 - 6.9e-42 141.8 0.3 1.6e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74618.1 - 0.072 13.7 0.0 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX74619.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain L27_1 PF09058.10 EAX74620.1 - 0.035 14.1 0.4 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 L27_1 Gly_rich PF12810.7 EAX74621.1 - 1.1e-53 182.7 40.4 1.5e-53 182.2 40.4 1.2 1 0 0 1 1 1 1 Glycine rich protein Trypan_PARP PF05887.11 EAX74623.1 - 0.031 14.3 8.5 0.041 13.9 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74623.1 - 1.9 8.9 5.6 2.4 8.6 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX74624.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74624.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX74625.1 - 2e-15 56.6 0.0 3.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX74626.1 - 3e-122 406.7 5.3 3.5e-122 406.5 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX74626.1 - 0.52 10.6 2.3 2.8 8.3 0.0 2.7 2 1 1 3 3 3 0 Rx N-terminal domain DUF4106 PF13388.6 EAX74628.1 - 2.5e-91 307.0 5.9 3.1e-91 306.7 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Arabino_trans_N PF17689.1 EAX74628.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain AAA_22 PF13401.6 EAX74630.1 - 3.6e-05 24.1 0.1 0.00023 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74630.1 - 6.2e-05 23.1 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX74630.1 - 8.6e-05 22.3 0.2 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX74630.1 - 0.00039 20.2 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74630.1 - 0.00068 19.5 0.5 0.0019 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX74630.1 - 0.0085 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX74630.1 - 0.059 12.8 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74630.1 - 0.067 13.6 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX74630.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX74630.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX74630.1 - 0.16 12.2 3.9 6.2 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX74630.1 - 1.1 9.7 4.7 0.44 11.0 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 His_Phos_2 PF00328.22 EAX74631.1 - 1.6e-11 44.2 0.0 2.9e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TMP PF05017.14 EAX74634.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74635.1 - 0.011 16.2 0.5 0.028 14.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX74636.1 - 4.9e-70 234.9 3.8 6.5e-70 234.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX74638.1 - 8.6e-155 513.3 12.2 1e-154 513.0 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX74638.1 - 0.033 14.5 0.8 2.4 8.5 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain DUF5398 PF17376.2 EAX74638.1 - 0.36 11.5 3.8 1 10.0 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX74638.1 - 0.5 10.8 5.2 4 8.0 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX74639.1 - 0.0042 16.7 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX74641.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX74641.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX74641.1 - 0.24 10.8 0.6 1.1 8.6 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain SH3BGR PF04908.15 EAX74642.1 - 0.036 14.2 1.4 0.039 14.1 1.4 1.1 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2897 PF11446.8 EAX74642.1 - 0.081 12.8 3.2 0.1 12.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74643.1 - 8.7e-58 194.3 5.0 9.7e-58 194.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74644.1 - 2e-05 25.0 2.0 8.1e-05 23.0 2.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74644.1 - 0.064 13.9 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Pox_D5 PF03288.16 EAX74647.1 - 2.3e-05 24.8 1.8 0.00016 22.1 1.8 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like IKKbetaNEMObind PF12179.8 EAX74648.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Mito_fiss_reg PF05308.11 EAX74650.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74650.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX74651.1 - 2.4e-155 515.1 13.0 2.9e-155 514.8 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX74651.1 - 0.12 12.8 0.3 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX74651.1 - 0.52 10.8 9.1 3.7 8.1 1.3 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX74651.1 - 0.75 10.1 5.2 13 6.1 0.1 3.7 4 1 1 5 5 5 0 Tup N-terminal DNA_pol_B_2 PF03175.13 EAX74652.1 - 7.5e-09 35.0 1.2 1.5e-08 33.9 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX74652.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX74652.1 - 0.16 11.9 0.0 0.95 9.5 0.0 2.1 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF2939 PF11159.8 EAX74653.1 - 0.018 15.4 0.4 0.025 15.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74653.1 - 0.95 8.4 2.2 1 8.3 2.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein PTR PF12789.7 EAX74654.1 - 6.3e-18 64.6 1.9 6.3e-18 64.6 1.9 4.5 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX74654.1 - 1.4e-05 24.8 4.6 0.00024 20.8 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX74654.1 - 0.28 11.7 1.7 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) YmaF PF12788.7 EAX74654.1 - 4.9 7.7 11.2 16 6.1 2.0 3.5 2 2 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX74654.1 - 7.4 7.0 14.5 12 6.4 0.2 4.1 4 0 0 4 4 4 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX74655.1 - 5.3e-138 458.3 10.1 8.1e-138 457.7 10.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74655.1 - 0.011 16.2 2.8 0.013 16.0 0.6 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX74655.1 - 0.9 10.0 6.7 5.9 7.4 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX74655.1 - 3.1 8.2 8.6 8.4 6.8 0.4 4.1 4 1 0 4 4 4 0 Tup N-terminal Phage-A118_gp45 PF10653.9 EAX74656.1 - 0.085 12.9 0.0 18 5.5 0.0 2.1 1 1 1 2 2 2 0 Protein gp45 of Bacteriophage A118 Pox_A32 PF04665.12 EAX74657.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74657.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74657.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74657.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2207 PF09972.9 EAX74659.1 - 0.0026 16.6 0.9 0.0028 16.5 0.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 EAX74659.1 - 0.0038 16.7 4.0 0.0043 16.5 4.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) BatD PF13584.6 EAX74659.1 - 0.0068 15.3 1.5 0.0079 15.1 1.5 1.1 1 0 0 1 1 1 1 Oxygen tolerance RIFIN PF02009.16 EAX74659.1 - 0.029 14.3 3.1 0.031 14.2 3.1 1.1 1 0 0 1 1 1 0 Rifin DUF4328 PF14219.6 EAX74659.1 - 0.039 13.5 2.4 0.049 13.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Synaptobrevin PF00957.21 EAX74659.1 - 0.049 13.4 0.9 0.067 13.0 0.9 1.2 1 0 0 1 1 1 0 Synaptobrevin Amnionless PF14828.6 EAX74659.1 - 0.14 10.9 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 EAX74659.1 - 0.15 12.4 2.8 0.2 12.0 2.8 1.3 1 1 0 1 1 1 0 Orf78 (ac78) DUF3357 PF11837.8 EAX74659.1 - 0.2 12.1 0.8 0.34 11.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TMEM154 PF15102.6 EAX74659.1 - 0.24 11.3 4.0 0.3 11.0 4.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.10 EAX74659.1 - 3.7 7.7 8.5 4.1 7.5 8.5 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4107 PF13389.6 EAX74660.1 - 8e-50 169.2 1.6 9.3e-50 168.9 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX74661.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX74662.1 - 1.1e-109 365.6 6.9 1.2e-109 365.4 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74662.1 - 0.04 13.4 0.4 0.061 12.8 0.3 1.3 1 1 0 1 1 1 0 Z1 domain DUF1043 PF06295.12 EAX74663.1 - 0.048 13.7 0.5 0.061 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX74664.1 - 0.024 15.0 0.5 0.03 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74664.1 - 1.3 8.0 2.7 1.4 7.9 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX74664.1 - 2.5 8.1 5.5 2.7 8.0 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74665.1 - 0.021 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX74666.1 - 2.1e-29 102.7 7.3 3.5e-29 102.0 7.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX74666.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF2939 PF11159.8 EAX74667.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF1043 PF06295.12 EAX74668.1 - 0.014 15.4 0.2 0.019 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX74668.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_N PF00345.20 EAX74669.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX74669.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX74669.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX74672.1 - 1.3e-111 371.9 6.9 1.4e-111 371.8 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FAS_N PF17828.1 EAX74673.1 - 0.023 14.7 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX74674.1 - 0.028 14.8 0.3 0.038 14.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74674.1 - 0.68 8.9 1.9 0.74 8.8 1.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX74674.1 - 2.2 8.3 4.6 2.3 8.2 4.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GPS2_interact PF15784.5 EAX74676.1 - 0.12 12.9 1.7 0.15 12.5 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74676.1 - 0.16 10.9 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MIG-14_Wnt-bd PF06664.12 EAX74677.1 - 0.0037 16.5 34.5 0.11 11.7 34.5 2.0 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4108 PF13390.6 EAX74678.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX74679.1 - 0.036 14.4 5.7 0.04 14.2 5.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family JMY PF15871.5 EAX74680.1 - 0.008 15.5 0.6 0.011 15.0 0.6 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX74680.1 - 0.1 12.5 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX74680.1 - 0.2 11.7 2.2 0.4 10.7 0.7 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX74681.1 - 1e-85 287.1 7.1 4.3e-85 285.0 7.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX74683.1 - 4.6e-05 23.4 0.3 4.6e-05 23.4 0.3 4.1 2 1 2 4 4 4 1 Phage tail repeat like EDR1 PF14381.6 EAX74683.1 - 0.031 14.0 0.1 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF445 PF04286.12 EAX74683.1 - 0.055 13.3 9.1 0.11 12.2 9.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX74683.1 - 0.059 13.1 0.1 0.25 11.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Tli4_C PF18426.1 EAX74683.1 - 0.19 12.0 1.0 4.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain MeaB PF03308.16 EAX74683.1 - 0.27 10.2 1.7 0.4 9.6 1.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX74683.1 - 0.52 10.8 0.0 0.52 10.8 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX74683.1 - 1.7 8.2 22.4 1.2e+04 -4.3 22.4 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX74686.1 - 6.3e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX74686.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX74686.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX74687.1 - 9.1e-156 516.4 14.9 1.1e-155 516.2 14.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX74687.1 - 0.035 14.3 0.7 0.068 13.4 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX74687.1 - 0.05 14.0 1.1 0.13 12.7 0.2 1.9 2 0 0 2 2 2 0 Fez1 DUF5398 PF17376.2 EAX74687.1 - 0.43 11.2 4.7 0.81 10.4 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX74687.1 - 0.89 10.1 8.5 1.8 9.1 1.0 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX74688.1 - 5.5e-55 185.2 7.3 6.1e-55 185.1 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX74689.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX74689.1 - 8.9 6.3 6.6 17 5.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74690.1 - 5.5e-63 211.2 5.8 6.2e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX74691.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74691.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74691.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74691.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74691.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74691.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74691.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Spo12 PF05032.12 EAX74692.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Ank_2 PF12796.7 EAX74693.1 - 1.1e-32 112.4 1.6 9.2e-12 45.4 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX74693.1 - 1.8e-32 111.3 2.7 3.2e-08 33.9 0.2 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX74693.1 - 9.4e-31 105.5 0.2 3.3e-07 30.5 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX74693.1 - 3.1e-25 85.5 0.5 5.7e-05 23.2 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAX74693.1 - 1e-21 76.3 2.7 0.00025 21.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX74693.1 - 0.003 17.5 0.8 1.4 8.9 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DUF3781 PF12636.7 EAX74695.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX74696.1 - 6.7e-08 32.3 1.1 7.4e-08 32.2 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74696.1 - 0.0049 16.5 0.1 0.0054 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) MSL1_dimer PF16801.5 EAX74696.1 - 0.048 13.4 1.3 0.11 12.3 1.3 1.6 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 IstB_IS21 PF01695.17 EAX74696.1 - 0.068 12.9 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74696.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX74697.1 - 0.029 14.8 0.8 0.063 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX74698.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat MMtag PF10159.9 EAX74700.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 Multiple myeloma tumor-associated DUF4108 PF13390.6 EAX74701.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX74704.1 - 1.1e-31 109.0 0.5 2.4e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX74704.1 - 0.066 13.2 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF4108 PF13390.6 EAX74705.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74706.1 - 1.6 8.7 4.7 3.1 7.7 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX74707.1 - 4.3e-111 370.2 7.7 5.2e-111 369.9 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX74707.1 - 0.072 12.6 0.7 0.1 12.1 0.6 1.3 1 1 0 1 1 1 0 Z1 domain DUF3839 PF12943.7 EAX74708.1 - 2.5e-119 397.1 12.0 3.1e-119 396.8 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74708.1 - 0.051 13.4 1.0 0.17 11.7 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX74708.1 - 0.14 12.6 3.3 2.4 8.7 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX74709.1 - 6e-11 42.2 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX74709.1 - 0.034 13.6 0.5 0.041 13.3 0.5 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF4543 PF15076.6 EAX74709.1 - 0.095 12.9 0.2 0.22 11.7 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) EssA PF10661.9 EAX74709.1 - 5.7 6.8 7.9 13 5.6 7.9 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX74710.1 - 1.8e-127 423.8 6.1 2.1e-127 423.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74710.1 - 0.26 11.7 1.3 1.1 9.8 0.5 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX74712.1 - 4.5e-96 322.6 5.6 4.5e-96 322.6 5.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX74712.1 - 0.66 8.5 4.0 0.82 8.2 4.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMP PF05017.14 EAX74713.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Caskin-tail PF16632.5 EAX74714.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin DUF2672 PF10878.8 EAX74715.1 - 0.024 14.6 0.9 0.078 12.9 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) IL3 PF02059.15 EAX74715.1 - 0.068 13.2 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Interleukin-3 IstB_IS21_ATP PF08483.11 EAX74716.1 - 4.8e-10 39.2 1.6 4.7e+02 0.8 0.0 14.6 18 0 0 18 18 18 0 IstB-like ATP binding N-terminal LDB19 PF13002.7 EAX74716.1 - 4.7e-08 33.0 10.5 5.4 6.7 0.0 6.7 2 1 4 7 7 7 5 Arrestin_N terminal like BORG_CEP PF14957.6 EAX74716.1 - 1.4e-06 29.5 41.0 5.5 8.2 3.9 8.5 1 1 4 5 5 5 4 Cdc42 effector KAAG1 PF15354.6 EAX74716.1 - 2.1e-05 25.0 40.8 2.3 8.8 0.6 8.7 1 1 8 10 10 10 4 Kidney-associated antigen 1 HTH_24 PF13412.6 EAX74716.1 - 0.00059 19.3 9.0 4.1 7.1 0.1 4.8 5 0 0 5 5 5 3 Winged helix-turn-helix DNA-binding PK_C PF02887.16 EAX74716.1 - 0.011 16.0 11.7 14 5.9 0.5 5.3 3 3 2 5 5 5 0 Pyruvate kinase, alpha/beta domain Baculo_p26 PF04766.12 EAX74716.1 - 0.073 12.5 19.8 0.55 9.6 1.2 3.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus p26 protein KilA-N PF04383.13 EAX74717.1 - 9.9e-40 134.9 0.7 2.4e-39 133.7 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74717.1 - 0.0068 17.0 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family DUF1493 PF07377.12 EAX74719.1 - 0.018 15.5 0.5 0.033 14.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) LPD28 PF18843.1 EAX74720.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 Large polyvalent protein associated domain 28 DUF2890 PF11081.8 EAX74720.1 - 0.11 12.6 0.1 0.11 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Mito_fiss_reg PF05308.11 EAX74721.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74721.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4108 PF13390.6 EAX74724.1 - 1.4e-63 213.1 6.5 1.5e-63 213.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74725.1 - 3.4e-05 24.2 2.2 0.00017 22.0 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX74725.1 - 0.077 13.6 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX74726.1 - 6.2e-09 35.2 1.0 1.2e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX74726.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX74726.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF1493 PF07377.12 EAX74727.1 - 0.016 15.7 0.4 0.029 14.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX74727.1 - 0.46 10.6 4.1 6.3 6.9 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4107 PF13389.6 EAX74728.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX74729.1 - 3.9e-151 501.3 16.4 4.8e-151 501.0 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74729.1 - 1.9 9.0 7.8 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX74731.1 - 0.027 14.4 8.1 0.043 13.8 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX74732.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX74732.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Collagen_bind_2 PF12904.7 EAX74734.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase PTR PF12789.7 EAX74735.1 - 6.1e-18 64.6 1.9 6.1e-18 64.6 1.9 5.2 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX74735.1 - 5.4e-05 22.9 10.5 0.089 12.4 2.1 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX74736.1 - 3.9e-05 23.3 3.5 6.9e-05 22.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX74736.1 - 0.0057 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX74736.1 - 0.01 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX74736.1 - 0.051 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MULE PF10551.9 EAX74737.1 - 2.9e-12 46.8 0.1 5.6e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF4852 PF16144.5 EAX74738.1 - 0.031 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) EF-hand_10 PF14788.6 EAX74739.1 - 0.0023 17.8 0.1 0.0072 16.2 0.1 1.9 1 0 0 1 1 1 1 EF hand YmaF PF12788.7 EAX74740.1 - 0.0048 17.4 2.9 0.14 12.7 0.3 2.1 1 1 1 2 2 2 2 YmaF family AAL_decarboxy PF03306.13 EAX74740.1 - 0.12 11.7 0.4 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase Phage_fiber PF03335.13 EAX74740.1 - 1.2 9.5 8.6 6 7.3 1.5 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat Annexin PF00191.20 EAX74741.1 - 0.017 15.2 0.3 0.083 13.0 0.3 2.1 1 1 1 2 2 2 0 Annexin Pox_A32 PF04665.12 EAX74742.1 - 6.5e-07 29.0 2.6 6.5e-07 29.0 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74742.1 - 3.7e-05 24.0 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74742.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74742.1 - 0.00026 21.0 3.1 0.00056 20.0 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74742.1 - 0.00059 19.6 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74742.1 - 0.0013 18.5 0.7 0.0027 17.5 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74742.1 - 0.0021 17.8 0.4 0.014 15.1 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74742.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX74742.1 - 0.062 13.7 0.1 0.52 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX74742.1 - 0.075 12.6 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX74742.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74742.1 - 0.21 11.8 4.4 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX74744.1 - 4.1e-07 30.5 0.2 7.7e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74745.1 - 3.9e-45 152.3 0.1 3.9e-45 152.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX74745.1 - 0.031 14.5 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX74746.1 - 2.3e-158 524.9 13.8 2.8e-158 524.6 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX74746.1 - 0.98 9.7 3.7 3.1 8.1 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX74746.1 - 1.7 9.2 7.5 2.1 8.8 1.0 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Meiosis_expr PF15163.6 EAX74747.1 - 0.068 13.9 0.8 0.11 13.2 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX74747.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated DUF3839 PF12943.7 EAX74748.1 - 3.3e-156 517.9 11.8 4.1e-156 517.6 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX74749.1 - 5.2e-157 520.5 13.5 6.5e-157 520.2 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX74749.1 - 0.084 13.3 0.3 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX74749.1 - 0.091 12.6 0.7 0.26 11.1 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX74749.1 - 0.58 10.6 6.4 2 8.9 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX74749.1 - 0.59 10.4 3.9 1.8 8.9 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain DUF4108 PF13390.6 EAX74750.1 - 2.7e-61 205.7 4.1 3e-61 205.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX74751.1 - 4.9e-05 23.7 2.1 0.00022 21.7 2.1 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX74751.1 - 0.032 13.3 1.0 0.046 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX74752.1 - 1.5e-62 209.7 6.2 1.7e-62 209.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX74752.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DAO_C PF16901.5 EAX74753.1 - 0.14 12.0 0.1 0.17 11.7 0.1 1.3 1 1 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF4108 PF13390.6 EAX74756.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74757.1 - 1.9e-120 400.8 11.7 2.4e-120 400.5 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74757.1 - 0.056 13.9 0.7 5.3 7.6 0.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX74757.1 - 0.098 12.5 0.8 0.3 10.9 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX74760.1 - 0.085 13.5 5.7 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX74761.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX74762.1 - 2.2e-21 76.3 4.7 3.9e-21 75.5 4.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX74762.1 - 0.053 12.8 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3781 PF12636.7 EAX74763.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX74764.1 - 4.6e-67 225.2 2.9 6.1e-67 224.8 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74764.1 - 0.12 12.7 0.7 0.15 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX74766.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX74768.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain JMY PF15871.5 EAX74769.1 - 0.014 14.8 0.5 0.02 14.2 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX74769.1 - 0.43 10.6 2.6 0.6 10.2 0.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) Trypan_PARP PF05887.11 EAX74770.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX74771.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PH_TFIIH PF08567.11 EAX74772.1 - 2.6 8.4 6.3 32 4.9 0.1 4.1 3 1 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF4108 PF13390.6 EAX74774.1 - 1.2e-62 210.0 8.4 1.4e-62 209.9 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74775.1 - 4.1e-149 494.7 14.9 5.1e-149 494.4 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74775.1 - 0.24 11.2 1.8 0.62 9.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX74775.1 - 0.45 10.8 3.7 1 9.6 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX74775.1 - 0.74 10.3 7.9 2 8.9 0.9 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX74776.1 - 6.6e-08 32.3 0.9 8e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74776.1 - 0.003 17.2 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74776.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74776.1 - 0.091 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX74776.1 - 0.13 12.7 1.3 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF3839 PF12943.7 EAX74777.1 - 3.3e-39 134.8 5.0 4.6e-39 134.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX74777.1 - 0.43 11.0 2.3 1.4 9.3 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain KilA-N PF04383.13 EAX74778.1 - 2.3e-31 107.9 0.0 3.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain C2-C2_1 PF11618.8 EAX74779.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 DNA_pol_B_2 PF03175.13 EAX74781.1 - 5.6e-07 28.8 3.9 1.9e-06 27.0 0.3 2.5 1 1 1 3 3 3 1 DNA polymerase type B, organellar and viral PhaP_Bmeg PF09602.10 EAX74781.1 - 0.1 12.5 0.1 1.2 9.1 0.1 2.1 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Isy1 PF06246.12 EAX74781.1 - 0.14 11.7 0.7 0.25 10.9 0.7 1.3 1 0 0 1 1 1 0 Isy1-like splicing family HTH_32 PF13565.6 EAX74782.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF4108 PF13390.6 EAX74785.1 - 3.9e-38 130.6 2.3 4.3e-38 130.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX74785.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Amidase02_C PF12123.8 EAX74786.1 - 0.05 13.3 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX74787.1 - 7.5e-154 510.2 12.0 9.5e-154 509.8 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74787.1 - 0.062 13.9 2.5 0.51 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX74789.1 - 4.2e-32 110.3 0.4 1.1e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX74790.1 - 2.2e-06 27.3 0.8 2.4e-06 27.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74790.1 - 0.0027 16.6 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX74790.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX74790.1 - 0.022 14.7 0.7 0.047 13.7 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX74790.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74790.1 - 0.085 12.8 0.2 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX74790.1 - 0.22 11.7 1.8 1.7 8.9 0.1 2.5 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain VirE PF05272.11 EAX74791.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX74791.1 - 0.083 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PcfK PF14058.6 EAX74792.1 - 0.15 12.4 10.6 0.2 11.9 10.6 1.4 1 1 0 1 1 1 0 PcfK-like protein AAA_22 PF13401.6 EAX74793.1 - 6.2e-05 23.3 0.0 0.00033 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74793.1 - 7.7e-05 22.8 3.2 0.00015 21.8 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74793.1 - 0.00038 20.3 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74793.1 - 0.00086 19.2 0.9 0.0028 17.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX74793.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74793.1 - 0.0089 15.8 0.3 0.18 11.5 0.0 2.3 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX74793.1 - 0.044 13.2 0.1 0.067 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX74793.1 - 0.073 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX74793.1 - 0.11 13.0 0.0 0.36 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX74793.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX74793.1 - 0.16 12.2 4.1 5.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF1043 PF06295.12 EAX74795.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX74795.1 - 0.1 12.6 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DDR PF08841.10 EAX74796.1 - 0.074 12.0 0.1 0.076 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX74797.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX74798.1 - 1.7e-07 30.9 2.5 1.7e-07 30.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74798.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74798.1 - 4.2e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74798.1 - 0.0002 21.4 3.6 0.00047 20.2 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74798.1 - 0.00058 19.7 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74798.1 - 0.0012 18.7 0.9 0.0023 17.8 0.9 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74798.1 - 0.0018 18.0 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74798.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74798.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74798.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74798.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX74798.1 - 0.38 11.0 4.0 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX74799.1 - 2.9e-116 387.1 8.0 3.4e-116 386.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX74800.1 - 8.5e-23 80.3 0.5 1.4e-22 79.6 0.5 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX74800.1 - 0.034 14.1 0.5 0.13 12.2 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin KilA-N PF04383.13 EAX74802.1 - 2.3e-11 43.5 0.5 6.8e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX74803.1 - 2.6e-73 245.5 4.3 3.1e-73 245.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74803.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX74804.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX74806.1 - 9.2e-07 28.6 2.6 9.2e-07 28.6 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74806.1 - 3e-05 24.3 0.2 0.00025 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74806.1 - 4.6e-05 23.2 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74806.1 - 0.00013 22.0 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74806.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74806.1 - 0.0015 18.4 0.8 0.0036 17.1 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX74806.1 - 0.0018 17.9 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX74806.1 - 0.012 16.0 0.0 0.026 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX74806.1 - 0.068 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX74806.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX74806.1 - 0.084 13.3 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX74806.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74806.1 - 0.37 11.1 3.9 10 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) ArsC PF03960.15 EAX74807.1 - 0.15 12.1 1.1 0.27 11.3 1.0 1.5 1 1 0 1 1 1 0 ArsC family DUF2939 PF11159.8 EAX74808.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX74808.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74809.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX74810.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74810.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74810.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74810.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74810.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74810.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX74811.1 - 2e-23 82.4 0.1 3.8e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX74812.1 - 6.8e-25 86.9 14.1 6.8e-25 86.9 14.1 3.9 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX74812.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) KilA-N PF04383.13 EAX74813.1 - 1.8e-42 143.7 0.1 2.9e-42 143.0 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX74813.1 - 0.025 14.8 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX74815.1 - 1.9e-110 368.0 12.3 2.4e-110 367.7 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX74816.1 - 1.9e-05 25.1 0.2 4.5e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX74817.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.7 5 1 1 6 6 6 1 Phage tail repeat like MeaB PF03308.16 EAX74817.1 - 0.099 11.6 0.6 0.18 10.8 0.6 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX74817.1 - 0.14 12.6 4.6 0.19 12.2 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX74817.1 - 0.29 10.9 9.6 0.31 10.8 8.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4108 PF13390.6 EAX74818.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74819.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74819.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX74821.1 - 2.2e-30 106.0 14.3 1.1e-29 103.6 14.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX74821.1 - 0.12 12.4 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Amidase02_C PF12123.8 EAX74822.1 - 0.0034 17.0 0.1 0.0086 15.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX74824.1 - 3.2e-155 514.7 12.1 4.1e-155 514.3 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX74824.1 - 0.11 12.4 1.0 0.36 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX74825.1 - 1.1e-156 519.4 14.0 1.4e-156 519.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74825.1 - 0.15 12.6 3.5 0.9 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX74825.1 - 0.25 11.7 1.3 0.52 10.6 0.2 2.1 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF4108 PF13390.6 EAX74826.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX74828.1 - 9.1e-06 25.3 2.3 1.3e-05 24.8 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74828.1 - 0.0026 17.4 0.1 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX74828.1 - 0.032 13.7 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX74828.1 - 0.038 13.7 0.2 0.18 11.6 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX74828.1 - 0.055 13.2 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX74828.1 - 0.12 12.4 2.1 1.1 9.2 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX74828.1 - 0.26 11.5 8.1 4.3 7.6 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) APG12 PF04110.13 EAX74828.1 - 0.29 11.5 2.3 0.41 11.1 1.0 1.9 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 XhlA PF10779.9 EAX74829.1 - 1.6e-05 25.0 111.1 0.49 10.6 6.4 9.9 2 2 8 10 10 10 8 Haemolysin XhlA BRX_N PF13713.6 EAX74829.1 - 2.7e-05 23.8 6.0 0.0049 16.6 1.0 3.4 2 0 0 2 2 2 2 Transcription factor BRX N-terminal domain DUF4404 PF14357.6 EAX74829.1 - 0.025 15.2 8.8 0.025 15.2 8.8 7.8 2 1 12 14 14 14 0 Domain of unknown function (DUF4404) TfoX_C PF04994.13 EAX74829.1 - 6.8 6.9 27.0 56 3.9 0.2 8.7 1 1 5 9 9 9 0 TfoX C-terminal domain Nup54 PF13874.6 EAX74829.1 - 6.9 6.8 53.6 4.2 7.5 1.6 6.0 2 1 5 7 7 7 0 Nucleoporin complex subunit 54 DUF724 PF05266.14 EAX74829.1 - 8.1 6.2 86.5 0.2 11.5 13.9 5.0 2 1 3 5 5 5 0 Protein of unknown function (DUF724) Pox_A32 PF04665.12 EAX74832.1 - 3.2e-05 23.5 1.7 3.2e-05 23.5 1.7 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX74832.1 - 9.7e-05 22.7 0.1 0.00061 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74832.1 - 0.00011 22.2 2.8 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74832.1 - 0.00078 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74832.1 - 0.0017 18.2 0.7 0.0035 17.2 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74832.1 - 0.0047 16.7 0.2 0.51 10.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX74832.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74832.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX74832.1 - 0.47 10.7 4.1 10 6.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MULE PF10551.9 EAX74833.1 - 1.4e-13 51.1 0.1 2.6e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX74833.1 - 0.047 13.4 1.2 0.078 12.7 1.2 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Pox_Ag35 PF03286.14 EAX74833.1 - 1.9 8.3 6.3 2.7 7.8 6.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mito_fiss_reg PF05308.11 EAX74834.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX74834.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PTR PF12789.7 EAX74835.1 - 2e-78 258.3 51.8 5.9e-33 112.7 13.2 5.5 2 2 3 5 5 5 3 Phage tail repeat like DUF2785 PF10978.8 EAX74835.1 - 0.054 13.3 3.0 1.4 8.7 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) DUF4116 PF13475.6 EAX74835.1 - 0.12 12.1 1.0 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX74835.1 - 7.8 7.2 11.3 12 6.6 0.3 4.0 2 1 4 6 6 6 0 Domain of unknown function (DUF4404) SL4P PF17618.2 EAX74836.1 - 0.12 12.5 2.7 6 7.0 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF1493 PF07377.12 EAX74836.1 - 0.12 12.8 1.4 0.15 12.5 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) AAA_22 PF13401.6 EAX74837.1 - 1.8e-05 25.1 0.2 0.00013 22.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX74837.1 - 0.00011 21.9 0.4 0.33 10.7 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX74837.1 - 0.00012 22.2 3.3 0.00021 21.3 3.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX74837.1 - 0.00039 20.2 0.1 0.00061 19.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74837.1 - 0.0012 18.6 1.0 0.0032 17.3 1.0 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX74837.1 - 0.0013 18.2 3.2 0.0014 18.2 1.5 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX74837.1 - 0.0091 16.3 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX74837.1 - 0.033 13.8 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX74837.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Elong_Iki1 PF10483.9 EAX74837.1 - 0.055 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX74837.1 - 0.056 13.9 0.1 0.44 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAX74837.1 - 0.22 11.2 0.0 0.22 11.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 EAX74839.1 - 4.6e-11 42.3 2.2 2.6e-10 39.8 2.2 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX74839.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Meiosis_expr PF15163.6 EAX74840.1 - 0.022 15.4 1.0 0.034 14.8 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX74840.1 - 0.17 11.7 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX74840.1 - 2 8.4 9.7 0.14 12.1 2.8 2.7 3 1 0 3 3 3 0 Spo12 family Gly-zipper_Omp PF13488.6 EAX74841.1 - 0.0063 16.5 9.0 0.01 15.8 9.0 1.3 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX74841.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74841.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PapD_N PF00345.20 EAX74843.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX74845.1 - 8.3e-29 100.7 6.8 1.2e-28 100.2 6.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX74845.1 - 0.065 13.5 0.7 0.2 11.9 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX74845.1 - 0.17 12.3 1.1 0.72 10.3 0.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB TMP PF05017.14 EAX74846.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74847.1 - 0.019 15.4 0.5 0.04 14.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Spo12 PF05032.12 EAX74849.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX74851.1 - 4.7e-42 142.4 0.5 1.2e-41 141.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX74851.1 - 0.36 10.8 3.2 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX74852.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74852.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74852.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74852.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX74857.1 - 4.5e-158 524.0 13.6 5.7e-158 523.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX74857.1 - 0.57 10.5 3.2 2.7 8.3 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX74857.1 - 0.74 10.3 7.0 2.4 8.7 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX74857.1 - 4.6 7.6 7.7 12 6.3 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal DUF5446 PF17522.2 EAX74859.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) TMP PF05017.14 EAX74860.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74861.1 - 0.086 13.3 0.7 0.23 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX74862.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74863.1 - 0.31 11.0 3.2 0.65 9.9 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1731 PF08338.11 EAX74865.1 - 0.19 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX74866.1 - 7.3e-79 264.6 10.5 9.6e-79 264.2 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74866.1 - 0.11 13.0 0.7 0.19 12.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX74868.1 - 4.7e-08 32.8 1.2 5.3e-08 32.6 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74868.1 - 0.0025 17.5 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) SAS4 PF15460.6 EAX74868.1 - 0.036 14.2 0.8 0.078 13.1 0.3 1.8 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 IstB_IS21 PF01695.17 EAX74868.1 - 0.064 13.0 0.0 0.096 12.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2805 PF10985.8 EAX74868.1 - 0.082 13.3 0.3 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX74868.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PadR PF03551.14 EAX74870.1 - 0.086 12.8 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family VirE PF05272.11 EAX74872.1 - 0.044 13.5 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.9 EAX74872.1 - 0.088 11.7 0.2 8 5.3 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF4108 PF13390.6 EAX74873.1 - 2.9e-57 192.6 4.7 3.2e-57 192.5 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX74874.1 - 0.14 12.0 3.0 0.28 11.1 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX74875.1 - 2.1e-109 364.7 7.7 2.3e-109 364.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74875.1 - 0.27 11.7 1.9 1.2 9.6 1.9 2.1 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX74876.1 - 2.9e-276 916.2 19.8 3.4e-276 916.0 19.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX74876.1 - 0.015 15.6 0.1 0.73 10.2 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated Ank_4 PF13637.6 EAX74877.1 - 3.5e-124 403.7 42.8 2e-14 53.7 0.2 12.6 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX74877.1 - 5.2e-116 379.5 81.9 2e-20 73.2 4.5 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX74877.1 - 1.5e-105 341.4 36.7 7.3e-09 35.7 0.1 13.0 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 EAX74877.1 - 1.5e-81 258.5 28.7 1.1e-06 28.4 0.1 13.0 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 EAX74877.1 - 4.5e-66 218.1 45.3 1.1e-09 38.4 0.0 8.1 3 2 7 10 10 10 10 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX74877.1 - 3.6e-17 62.4 2.0 0.019 15.2 0.0 8.0 1 1 6 8 8 8 4 N terminal of Calcineurin-like phosphoesterase SAB PF04382.13 EAX74877.1 - 3.3e-05 23.9 39.5 47 4.2 0.1 12.7 13 0 0 13 13 13 0 SAB domain DUF3130 PF11328.8 EAX74877.1 - 0.0015 18.7 21.6 4.3 7.6 0.2 6.9 1 1 2 7 7 7 2 Protein of unknown function (DUF3130 RNase_PH_C PF03725.15 EAX74877.1 - 0.0021 18.1 17.0 21 5.2 0.1 8.1 6 4 3 10 10 10 0 3' exoribonuclease family, domain 2 Ribosomal_S6 PF01250.17 EAX74877.1 - 0.53 10.6 14.7 45 4.4 0.1 6.1 1 1 2 6 6 6 0 Ribosomal protein S6 DUF2028 PF09667.10 EAX74877.1 - 0.59 10.1 5.1 81 3.1 0.1 4.6 2 2 1 5 5 5 0 Domain of unknown function (DUF2028) ApbA_C PF08546.11 EAX74877.1 - 3.5 7.8 16.5 98 3.2 0.1 6.9 1 1 3 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal Lipoprotein_3 PF00938.17 EAX74877.1 - 4.8 7.4 26.5 53 4.1 0.1 8.2 2 2 9 11 11 11 0 Lipoprotein Clathrin PF00637.20 EAX74877.1 - 9.1 6.1 24.7 49 3.8 0.1 7.3 1 1 7 9 9 9 0 Region in Clathrin and VPS Trypan_PARP PF05887.11 EAX74878.1 - 0.073 13.1 9.7 0.11 12.4 9.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX74878.1 - 1.8 9.0 5.4 2.6 8.5 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX74880.1 - 0.023 15.1 0.6 0.03 14.8 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAX74880.1 - 0.038 14.4 2.2 0.038 14.4 2.2 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DNA_pol_B_2 PF03175.13 EAX74881.1 - 4.9e-23 81.7 3.4 7e-23 81.2 3.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX74883.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX74883.1 - 1.3 8.0 2.7 1.4 7.8 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX74883.1 - 1.5 8.8 5.6 1.6 8.7 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX74884.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX74885.1 - 1e-06 28.4 2.4 1.5e-06 27.9 2.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74885.1 - 0.0051 16.5 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74885.1 - 0.065 13.0 0.2 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX74885.1 - 0.066 12.7 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX74885.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX74885.1 - 0.51 10.5 8.5 4.8 7.4 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Spo12 PF05032.12 EAX74886.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX74887.1 - 1e-18 67.2 0.1 1.3e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX74887.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4107 PF13389.6 EAX74888.1 - 5.1e-67 225.1 9.8 1.8e-66 223.3 9.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX74888.1 - 0.11 12.9 0.4 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX74889.1 - 7.7e-157 519.9 12.8 9.5e-157 519.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74889.1 - 3.3 8.2 7.8 3.4 8.2 1.7 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX74890.1 - 5.8e-07 29.2 0.8 7.1e-07 28.9 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74890.1 - 0.0027 16.7 0.0 0.003 16.5 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX74890.1 - 0.0044 16.7 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74890.1 - 0.087 12.5 0.1 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74890.1 - 0.12 12.4 0.5 1.4 8.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) GGDEF PF00990.21 EAX74891.1 - 0.023 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain GAGA_bind PF06217.12 EAX74891.1 - 0.061 13.6 4.9 0.077 13.3 4.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PcfK PF14058.6 EAX74891.1 - 1.5 9.1 15.3 2 8.7 15.3 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX74892.1 - 1.2e-57 193.9 4.7 1.3e-57 193.7 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX74894.1 - 0.00065 20.2 0.2 0.0012 19.3 0.2 1.4 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74895.1 - 5.6e-12 45.5 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX74895.1 - 0.26 10.7 0.2 0.53 9.7 0.2 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX74896.1 - 1.5e-79 266.9 10.6 2e-79 266.5 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74896.1 - 0.069 13.7 0.5 0.12 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX74896.1 - 0.079 12.5 0.6 0.41 10.1 0.0 2.3 2 1 1 3 3 3 0 SLOG cluster2 Noggin PF05806.12 EAX74897.1 - 0.058 13.3 1.1 0.074 13.0 1.1 1.1 1 0 0 1 1 1 0 Noggin DUF4106 PF13388.6 EAX74898.1 - 7.8e-68 229.6 2.7 9.3e-68 229.4 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX74899.1 - 3.5e-157 521.1 12.1 4e-157 520.9 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74899.1 - 0.097 13.1 5.9 1.7 9.2 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX74899.1 - 0.11 13.0 1.3 0.79 10.1 0.2 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX74899.1 - 1.1 9.6 4.9 8.3 6.8 0.1 3.3 2 2 2 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX74900.1 - 4.7e-42 142.4 0.3 1.2e-41 141.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74900.1 - 0.0055 17.3 0.1 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family KilA-N PF04383.13 EAX74902.1 - 7.2e-11 41.9 0.2 1.4e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX74902.1 - 0.22 10.9 0.2 0.53 9.7 0.2 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX74903.1 - 1.1e-80 270.7 10.5 1.3e-80 270.3 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX74903.1 - 0.33 11.3 1.9 1.3 9.4 1.0 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain PTR PF12789.7 EAX74904.1 - 2.4e-48 162.0 28.2 1.5e-32 111.5 14.5 3.6 2 2 1 3 3 3 2 Phage tail repeat like PBP5_C PF07943.13 EAX74904.1 - 0.024 14.9 0.2 0.18 12.1 0.0 2.3 2 1 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DUF3839 PF12943.7 EAX74905.1 - 1.1e-110 368.8 7.2 1.4e-110 368.5 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX74905.1 - 0.23 11.8 1.2 0.47 10.8 1.2 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3839 PF12943.7 EAX74908.1 - 2.8e-148 491.9 10.8 3.7e-148 491.5 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX74908.1 - 0.039 14.4 0.5 0.098 13.1 0.1 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX74908.1 - 0.049 14.1 3.3 2 8.9 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX74908.1 - 0.088 13.2 0.2 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KilA-N PF04383.13 EAX74909.1 - 1.8e-45 153.4 0.3 4.2e-45 152.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74909.1 - 0.056 14.1 0.2 0.2 12.3 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX74909.1 - 0.51 10.4 3.7 6.1 6.9 0.3 2.4 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX74910.1 - 3.9e-05 24.1 0.1 9.9e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX74910.1 - 0.0038 16.8 0.7 0.089 12.3 0.2 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX74910.1 - 0.022 14.6 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX74912.1 - 7.7e-05 22.3 0.4 7.8e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX74912.1 - 0.093 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX74913.1 - 4.7e-79 265.3 9.7 6e-79 264.9 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX74913.1 - 0.44 10.6 2.7 2.1 8.5 1.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PTR PF12789.7 EAX74914.1 - 9.5e-28 96.0 12.2 9.5e-28 96.0 12.2 3.6 3 1 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX74914.1 - 0.037 13.7 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Phage_fiber PF03335.13 EAX74914.1 - 0.98 9.8 13.3 4.4 7.7 1.1 3.6 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4795 PF16043.5 EAX74914.1 - 6.1 6.4 15.0 17 5.0 8.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX74915.1 - 2.9e-127 423.1 6.7 3.4e-127 422.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMEM154 PF15102.6 EAX74916.1 - 1.5e-05 24.9 0.2 2.3e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF2140 PF09911.9 EAX74916.1 - 0.0014 18.3 3.2 0.062 12.8 0.9 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2140) DUF5385 PF17359.2 EAX74916.1 - 0.0015 18.1 3.4 0.0025 17.4 3.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5385) EphA2_TM PF14575.6 EAX74916.1 - 0.0018 19.1 1.0 0.0034 18.2 1.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain 7TM_GPCR_Srh PF10318.9 EAX74916.1 - 0.0039 16.3 0.1 0.0051 15.9 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sru PF10322.9 EAX74916.1 - 0.004 16.5 0.1 0.0058 16.0 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru DUF4834 PF16118.5 EAX74916.1 - 0.0061 17.5 2.3 0.011 16.7 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Shisa PF13908.6 EAX74916.1 - 0.0076 16.5 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator 7TM_GPCR_Srx PF10328.9 EAX74916.1 - 0.0091 15.6 0.3 0.015 14.9 0.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Orf78 PF06024.12 EAX74916.1 - 0.013 15.8 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF4083 PF13314.6 EAX74916.1 - 0.019 14.9 4.1 0.036 14.0 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Baculo_11_kDa PF06143.11 EAX74916.1 - 0.022 14.4 1.4 0.046 13.3 1.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family PRIMA1 PF16101.5 EAX74916.1 - 0.022 14.8 0.5 0.038 14.0 0.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Phage_holin_3_6 PF07332.11 EAX74916.1 - 0.025 14.6 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AsmA_2 PF13502.6 EAX74916.1 - 0.03 13.8 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region 7TM_GPCR_Srv PF10323.9 EAX74916.1 - 0.035 13.5 0.2 0.061 12.7 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Podoplanin PF05808.11 EAX74916.1 - 0.072 13.2 4.2 0.1 12.7 3.5 1.5 1 1 0 1 1 1 0 Podoplanin ECSCR PF15820.5 EAX74916.1 - 0.073 12.9 3.0 0.18 11.7 2.3 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF997 PF06196.12 EAX74916.1 - 0.073 13.1 2.2 0.13 12.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) OAD_gamma PF04277.13 EAX74916.1 - 0.086 13.4 3.0 0.18 12.4 3.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Synaptobrevin PF00957.21 EAX74916.1 - 0.11 12.4 2.6 0.2 11.4 2.6 1.5 1 0 0 1 1 1 0 Synaptobrevin ODV-E18 PF10717.9 EAX74916.1 - 0.13 12.2 7.0 0.3 11.0 7.0 1.7 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4381 PF14316.6 EAX74916.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Chordopox_A13L PF05961.11 EAX74916.1 - 0.17 12.1 3.5 0.17 12.1 0.8 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Sigma_reg_N PF13800.6 EAX74916.1 - 0.22 11.9 4.4 0.38 11.1 2.1 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Syndecan PF01034.20 EAX74916.1 - 0.22 11.5 1.4 0.41 10.6 1.4 1.4 1 0 0 1 1 1 0 Syndecan domain DUF929 PF06053.11 EAX74916.1 - 0.31 10.3 5.4 0.21 10.8 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF929) ASFV_J13L PF05568.11 EAX74916.1 - 0.49 10.1 6.0 0.24 11.2 2.6 2.1 2 1 0 2 2 2 0 African swine fever virus J13L protein SID-1_RNA_chan PF13965.6 EAX74916.1 - 0.53 8.6 4.0 0.74 8.1 0.7 2.4 2 1 1 3 3 3 0 dsRNA-gated channel SID-1 TPPK_C PF12555.8 EAX74916.1 - 2.1 8.4 9.8 3.5 7.7 9.8 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF2749 PF10907.8 EAX74916.1 - 2.4 8.4 5.4 0.58 10.4 2.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2749) FeoB_associated PF12669.7 EAX74916.1 - 3.3 8.2 8.1 6.4 7.3 8.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Collectrin PF16959.5 EAX74916.1 - 4 7.2 7.4 1.5 8.5 4.8 1.7 2 0 0 2 2 2 0 Renal amino acid transporter DUF4378 PF14309.6 EAX74918.1 - 0.047 14.1 0.2 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) La PF05383.17 EAX74918.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 La domain KilA-N PF04383.13 EAX74919.1 - 2.6e-44 149.6 1.1 3.8e-44 149.1 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74919.1 - 0.014 16.0 0.1 0.053 14.1 0.0 2.0 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX74920.1 - 2.1e-65 220.6 4.6 2.7e-65 220.2 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX74921.1 - 5.5e-10 38.7 0.9 1.1e-09 37.7 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ribosomal_S6e PF01092.19 EAX74921.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e DUF4106 PF13388.6 EAX74922.1 - 8.2e-94 315.2 5.5 8.2e-94 315.2 5.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF4107 PF13389.6 EAX74923.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX74924.1 - 3.3e-07 30.8 0.2 6.2e-07 29.9 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX74924.1 - 0.17 12.6 0.5 0.51 11.1 0.5 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3839 PF12943.7 EAX74925.1 - 1.1e-39 136.3 4.6 1.5e-39 135.9 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX74925.1 - 0.2 12.1 1.2 2.1 8.7 0.6 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain FliJ PF02050.16 EAX74926.1 - 0.022 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein SL4P PF17618.2 EAX74928.1 - 0.41 10.7 3.4 6.5 6.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX74929.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX74930.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP PapD_N PF00345.20 EAX74932.1 - 0.045 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX74932.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX74933.1 - 2.4e-05 24.3 0.6 2.4e-05 24.3 0.6 3.7 3 0 0 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX74933.1 - 0.02 14.7 3.2 0.028 14.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX74933.1 - 0.03 14.0 0.1 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX74933.1 - 0.054 13.1 13.6 0.042 13.4 8.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX74933.1 - 0.085 13.3 0.5 0.48 10.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX74933.1 - 0.18 10.7 0.9 0.3 10.0 0.9 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2120 PF09893.9 EAX74933.1 - 0.21 11.7 1.5 1.2 9.3 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4841 PF16129.5 EAX74935.1 - 0.086 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DUF2897 PF11446.8 EAX74936.1 - 0.44 10.5 3.7 0.81 9.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74937.1 - 7.7e-57 191.2 4.9 8.6e-57 191.1 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX74937.1 - 0.13 12.6 0.5 7.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX74939.1 - 7e-78 261.4 9.5 8.9e-78 261.1 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX74939.1 - 0.068 13.4 0.1 0.38 11.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF29 APC_u14 PF16635.5 EAX74939.1 - 0.12 12.9 1.0 0.23 12.0 1.0 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr T5orf172 PF10544.9 EAX74940.1 - 1.5e-06 28.7 0.5 3e-06 27.7 0.5 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74942.1 - 5.2e-16 58.5 0.5 1.4e-15 57.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX74942.1 - 0.024 15.2 0.0 0.055 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF4378 PF14309.6 EAX74944.1 - 0.0076 16.6 0.1 0.023 15.1 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4378) La PF05383.17 EAX74944.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 La domain Amidase02_C PF12123.8 EAX74946.1 - 0.0039 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX74947.1 - 5.3e-21 75.3 3.7 5.3e-21 75.3 3.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX74947.1 - 0.031 12.9 4.4 0.038 12.6 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PTR PF12789.7 EAX74948.1 - 3e-49 164.9 40.5 5.6e-31 106.4 13.4 4.3 3 2 2 5 5 4 2 Phage tail repeat like GUN4_N PF16416.5 EAX74948.1 - 0.42 10.6 1.9 4.7 7.3 0.3 2.8 1 1 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal PH_TFIIH PF08567.11 EAX74948.1 - 0.52 10.7 5.5 27 5.2 0.3 3.7 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DNA_pol_B_2 PF03175.13 EAX74949.1 - 7.6e-07 28.4 1.4 9.8e-07 28.0 0.7 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX74949.1 - 0.094 12.3 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX74949.1 - 0.12 12.4 0.1 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX74950.1 - 4.4e-80 268.6 10.7 5.8e-80 268.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX74950.1 - 0.062 13.9 0.9 0.099 13.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX74950.1 - 0.14 11.6 0.7 0.82 9.1 0.0 2.4 2 1 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX74950.1 - 0.33 11.4 1.6 0.97 9.9 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX74951.1 - 2.3e-07 30.6 0.6 1.7e-06 27.7 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74951.1 - 0.049 13.3 0.1 1 9.0 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74951.1 - 0.092 12.6 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74951.1 - 0.21 11.8 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX74952.1 - 1.4e-120 401.2 11.9 1.7e-120 400.9 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74952.1 - 0.0059 17.0 2.7 1.8 9.0 0.0 3.3 2 1 1 3 3 3 3 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX74953.1 - 0.0073 16.2 0.1 0.014 15.3 0.0 1.5 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX74953.1 - 0.021 14.8 0.5 0.026 14.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX74955.1 - 3.6e-121 403.2 12.0 4.4e-121 402.9 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX74955.1 - 0.017 15.5 1.0 5.3 7.6 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX74955.1 - 0.21 11.4 1.5 0.52 10.1 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX74956.1 - 1.2e-41 141.1 0.1 2.5e-41 140.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX74956.1 - 0.01 16.0 0.4 0.024 14.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX74956.1 - 0.014 14.7 0.2 0.058 12.6 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX74956.1 - 0.069 11.7 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Amidase02_C PF12123.8 EAX74957.1 - 0.0093 15.6 0.1 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX74958.1 - 9.3e-09 34.7 1.0 1.7e-08 33.8 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX74958.1 - 0.0079 14.9 1.8 0.092 11.4 1.8 2.3 1 1 0 1 1 1 1 DNA polymerase family B KilA-N PF04383.13 EAX74959.1 - 1.6e-31 108.5 0.8 2.9e-31 107.6 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX74960.1 - 4.8e-07 30.3 0.1 1e-06 29.2 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX74960.1 - 0.0062 16.4 0.1 0.04 13.8 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain RNA_bind PF08675.11 EAX74960.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA binding domain DUF3839 PF12943.7 EAX74961.1 - 5.2e-112 373.2 12.9 6.9e-112 372.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) IKKbetaNEMObind PF12179.8 EAX74964.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PTR PF12789.7 EAX74965.1 - 2.7e-37 126.6 25.4 2.7e-32 110.6 13.8 5.0 4 2 2 6 6 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX74965.1 - 0.059 13.1 0.9 0.099 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX74967.1 - 9e-62 207.2 7.0 1e-61 207.1 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX74967.1 - 0.037 13.1 0.1 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF3839 PF12943.7 EAX74969.1 - 3.2e-25 89.0 5.0 4.7e-25 88.5 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX74969.1 - 0.044 13.9 1.0 0.16 12.1 1.0 2.0 1 1 0 1 1 1 0 Associated with zinc fingers DUF2897 PF11446.8 EAX74970.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX74971.1 - 2.6e-63 212.2 6.1 2.9e-63 212.1 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX74972.1 - 3.3e-34 117.1 0.2 4.5e-34 116.7 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX74972.1 - 0.024 14.6 0.5 0.028 14.4 0.5 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAX74973.1 - 2.3e-81 272.8 10.3 3.4e-81 272.3 10.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX74973.1 - 0.075 13.3 1.1 0.24 11.7 0.1 2.4 3 0 0 3 3 3 0 PRD domain Podoplanin PF05808.11 EAX74976.1 - 0.044 13.9 3.1 0.085 13.0 0.0 2.2 2 0 0 2 2 2 0 Podoplanin Syndecan PF01034.20 EAX74976.1 - 0.089 12.7 1.2 0.17 11.8 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain MtrF PF09472.10 EAX74976.1 - 0.12 11.7 3.0 0.23 10.9 3.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3474 PF11960.8 EAX74976.1 - 0.15 12.2 0.4 3.3 7.9 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3474) TQ PF18202.1 EAX74976.1 - 0.76 10.3 7.6 0.67 10.5 1.9 2.9 3 0 0 3 3 3 0 T-Q ester bond containing domain DUF5445 PF17520.2 EAX74980.1 - 5.3 7.0 11.3 2.8 7.9 3.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5445) DUF3839 PF12943.7 EAX74981.1 - 4e-75 252.4 9.4 5.3e-75 252.0 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Com_YlbF PF06133.11 EAX74981.1 - 1 10.0 6.0 5.7 7.6 1.0 3.0 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF4108 PF13390.6 EAX74983.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX74984.1 - 1.9e-118 394.3 8.5 5.7e-118 392.7 8.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) AAA_22 PF13401.6 EAX74986.1 - 3.6e-05 24.1 0.1 0.00023 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX74986.1 - 6.2e-05 23.1 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX74986.1 - 8.6e-05 22.3 0.2 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX74986.1 - 0.00039 20.2 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX74986.1 - 0.00068 19.5 0.5 0.0019 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX74986.1 - 0.0085 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX74986.1 - 0.059 12.8 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX74986.1 - 0.067 13.6 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX74986.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX74986.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX74986.1 - 0.16 12.2 3.9 6.2 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX74986.1 - 1.1 9.7 4.7 0.44 11.0 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 Pox_A32 PF04665.12 EAX74987.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX74987.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX74987.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX74987.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Gly-zipper_Omp PF13488.6 EAX74988.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX74988.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX74988.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4107 PF13389.6 EAX74989.1 - 1.3e-51 175.0 1.6 1.8e-51 174.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX74991.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX74991.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX74991.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX74991.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PSP PF04046.16 EAX74993.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX74994.1 - 0.062 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX74995.1 - 0.052 14.0 0.2 0.089 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Chal_sti_synt_N PF00195.19 EAX74997.1 - 0.024 14.1 0.6 0.047 13.1 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX74998.1 - 2.1e-62 210.8 3.7 2.3e-62 210.6 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX75000.1 - 0.043 13.7 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75000.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX75001.1 - 4.1e-46 157.4 3.6 5.4e-46 157.0 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rab5-bind PF09311.11 EAX75001.1 - 0.0089 15.4 0.4 0.011 15.2 0.4 1.1 1 0 0 1 1 1 1 Rabaptin-like protein BrkDBD PF09607.10 EAX75001.1 - 0.087 12.6 0.7 0.19 11.6 0.7 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain KilA-N PF04383.13 EAX75002.1 - 5e-44 148.7 0.1 5e-44 148.7 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX75002.1 - 0.039 14.1 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX75003.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain TMP PF05017.14 EAX75005.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX75007.1 - 1.5e-06 28.6 0.2 3e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Pox_D5 PF03288.16 EAX75008.1 - 2.7e-05 24.6 2.9 0.00015 22.2 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Tho2 PF11262.8 EAX75009.1 - 0.037 13.2 1.4 0.04 13.1 1.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX75009.1 - 0.53 10.2 8.3 0.21 11.5 2.9 2.5 3 0 0 3 3 3 0 Spo12 family GPS2_interact PF15784.5 EAX75012.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75012.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX75013.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Chal_sti_synt_N PF00195.19 EAX75014.1 - 0.035 13.5 0.4 0.063 12.7 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX75015.1 - 1.1e-07 31.6 1.6 1.7e-07 30.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2897 PF11446.8 EAX75016.1 - 4.6 7.2 5.9 9.7 6.2 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX75017.1 - 5.1e-07 29.4 2.0 5.1e-07 29.4 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75017.1 - 4.5e-05 23.2 0.2 0.41 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX75017.1 - 8.4e-05 22.9 0.1 0.00052 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX75017.1 - 8.8e-05 22.6 2.7 0.00019 21.5 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75017.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX75017.1 - 0.0025 17.5 0.4 0.018 14.7 0.1 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX75017.1 - 0.0027 17.5 0.5 0.0046 16.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75017.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX75017.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX75017.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX75017.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX75017.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX75017.1 - 0.5 10.6 3.3 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pep1_7 PF17232.2 EAX75018.1 - 5.3e-06 26.8 0.7 0.015 15.7 0.0 2.9 2 1 1 3 3 3 2 Elicitor peptide 1-7 Peroxin-13_N PF04088.13 EAX75018.1 - 0.047 14.0 0.1 2.9 8.2 0.0 2.5 1 1 2 3 3 3 0 Peroxin 13, N-terminal region SPX PF03105.19 EAX75018.1 - 0.064 13.2 3.8 0.083 12.8 3.8 1.1 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 EAX75018.1 - 0.1 13.6 0.5 15 6.6 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4834) DUF2615 PF11027.8 EAX75018.1 - 0.23 11.6 4.7 0.4 10.8 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Ntox24 PF15529.6 EAX75018.1 - 1.6 9.1 6.4 18 5.7 0.2 2.9 3 0 0 3 3 3 0 Bacterial toxin 24 DNA_pol_B_2 PF03175.13 EAX75019.1 - 6.7e-10 38.4 3.1 4.3e-09 35.8 3.1 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX75019.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycoprotein UL132 SRP68 PF16969.5 EAX75020.1 - 6.7e-28 98.0 0.1 7.8e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 RPN7 PF10602.9 EAX75020.1 - 0.0056 16.4 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 EAX75020.1 - 0.17 12.1 1.0 0.48 10.7 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MULE PF10551.9 EAX75021.1 - 1.2e-12 48.1 0.1 2.3e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX75021.1 - 0.087 12.5 1.1 0.15 11.7 1.1 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX75021.1 - 0.42 10.9 5.6 0.95 9.7 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX75021.1 - 0.78 9.5 5.3 1.2 8.9 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KilA-N PF04383.13 EAX75022.1 - 2.2e-34 117.7 1.4 5.2e-34 116.5 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain RPAP3_C PF13877.6 EAX75022.1 - 0.014 15.9 0.7 0.06 13.9 0.1 2.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 T5orf172 PF10544.9 EAX75023.1 - 4.2e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PSP PF04046.16 EAX75025.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX75026.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX75027.1 - 0.022 15.2 0.8 0.037 14.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) MORN_2 PF07661.13 EAX75030.1 - 0.013 15.6 0.0 32 5.2 0.0 3.9 3 0 0 3 3 3 0 MORN repeat variant DUF3839 PF12943.7 EAX75032.1 - 2e-80 269.7 10.4 2.6e-80 269.4 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75032.1 - 0.15 11.9 1.0 0.59 10.0 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX75033.1 - 1.4e-149 496.2 11.7 1.6e-149 496.0 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75033.1 - 0.046 13.6 0.5 0.18 11.7 0.5 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX75033.1 - 0.45 10.8 3.3 0.91 9.8 0.1 2.8 2 1 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX75033.1 - 1.2 9.6 5.5 1.5 9.4 0.9 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX75034.1 - 0.12 12.5 0.5 0.12 12.4 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX75034.1 - 0.67 9.4 2.6 0.67 9.4 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NAD_Gly3P_dh_C PF07479.14 EAX75035.1 - 8.3e-37 126.6 0.3 9.7e-37 126.4 0.3 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF4108 PF13390.6 EAX75039.1 - 6.2e-59 198.0 6.4 6.8e-59 197.9 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX75040.1 - 2.4e-05 24.7 2.5 0.00011 22.6 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75040.1 - 0.03 14.9 0.1 0.054 14.1 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75040.1 - 0.049 13.6 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4107 PF13389.6 EAX75042.1 - 5.6e-12 46.1 0.8 6.3e-12 45.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX75043.1 - 5.1e-157 520.6 16.0 6.4e-157 520.2 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75043.1 - 0.057 13.7 0.4 1.1 9.6 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain Fez1 PF06818.15 EAX75043.1 - 0.067 13.6 1.7 0.14 12.6 0.3 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX75043.1 - 0.11 12.3 1.5 0.32 10.9 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75043.1 - 1.1 9.7 7.6 2.5 8.6 0.8 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HNH_3 PF13392.6 EAX75044.1 - 1.4e-07 31.2 0.3 2.3e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 HNH endonuclease SKA2 PF16740.5 EAX75045.1 - 0.12 12.2 0.0 1 9.2 0.0 2.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 CTD PF12815.7 EAX75046.1 - 8e-16 58.4 27.2 0.0011 19.5 4.7 6.3 1 1 4 5 5 5 5 Spt5 C-terminal nonapeptide repeat binding Spt4 SR1P PF13790.6 EAX75046.1 - 0.23 11.6 5.8 4.2e+02 1.2 0.0 7.4 6 0 0 6 6 6 0 SR1 protein LAMTOR5 PF16672.5 EAX75046.1 - 6.9 6.7 11.4 12 5.9 0.5 4.1 3 1 2 5 5 5 0 Ragulator complex protein LAMTOR5 DUF4108 PF13390.6 EAX75047.1 - 6.1e-77 256.4 12.7 7e-77 256.2 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PIP49_N PF14875.6 EAX75048.1 - 0.18 11.6 3.5 3.3 7.6 1.4 2.0 1 1 1 2 2 2 0 N-term cysteine-rich ER, FAM69 Pox_A32 PF04665.12 EAX75049.1 - 3.9e-07 29.8 3.8 5.7e-07 29.2 3.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75049.1 - 0.0026 17.4 0.2 0.0033 17.1 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75049.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX75049.1 - 0.061 13.1 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX75049.1 - 0.2 11.7 2.4 1.2 9.2 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX75049.1 - 0.53 10.5 8.7 4.4 7.5 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) IstB_IS21 PF01695.17 EAX75050.1 - 7.2e-06 25.8 0.2 0.084 12.6 0.0 2.5 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX75050.1 - 1.6e-05 24.5 1.9 1.6e-05 24.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75050.1 - 2.7e-05 24.5 0.2 0.00016 21.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX75050.1 - 7.1e-05 22.9 2.3 0.00014 21.9 2.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75050.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75050.1 - 0.0013 18.6 0.4 0.0026 17.6 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75050.1 - 0.0017 18.0 0.3 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75050.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX75050.1 - 0.053 13.1 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX75050.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX75050.1 - 0.092 13.2 0.1 0.66 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3783 PF12646.7 EAX75050.1 - 0.12 12.4 0.8 1.6 8.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75054.1 - 1.4e-81 273.5 10.5 1.8e-81 273.2 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX75054.1 - 0.081 13.5 0.3 0.12 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX75054.1 - 0.21 11.4 1.5 0.81 9.5 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase HTH_ABP1_N PF18107.1 EAX75055.1 - 0.038 13.7 3.0 0.17 11.6 0.1 2.3 1 1 1 2 2 2 0 Fission yeast centromere protein N-terminal domain PAP1 PF08601.10 EAX75057.1 - 0.0029 17.4 9.0 0.0035 17.1 9.0 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 DUF572 PF04502.13 EAX75057.1 - 0.0037 17.0 26.8 0.0042 16.8 26.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Hamartin PF04388.12 EAX75057.1 - 0.061 12.0 10.9 0.076 11.7 10.9 1.2 1 0 0 1 1 1 0 Hamartin protein DUF5427 PF10310.9 EAX75057.1 - 0.069 12.1 29.2 0.1 11.5 29.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MAP7 PF05672.11 EAX75057.1 - 0.42 10.3 77.0 0.42 10.3 56.6 2.0 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Caldesmon PF02029.15 EAX75057.1 - 0.54 9.0 51.9 0.71 8.6 51.9 1.1 1 0 0 1 1 1 0 Caldesmon Mitofilin PF09731.9 EAX75057.1 - 0.63 8.8 42.1 0.8 8.5 42.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 EAX75057.1 - 1.6 8.6 36.2 2.3 8.1 36.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GREB1 PF15782.5 EAX75057.1 - 5.1 4.1 16.9 6.3 3.8 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 EAX75057.1 - 5.7 5.7 21.9 7.5 5.3 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Asp-B-Hydro_N PF05279.11 EAX75057.1 - 10 6.1 43.2 15 5.6 43.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2486 PF10667.9 EAX75058.1 - 0.0036 17.6 5.2 0.0043 17.3 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) DUF3035 PF11233.8 EAX75058.1 - 0.0094 16.2 3.9 0.012 15.9 3.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3035) DUF938 PF06080.12 EAX75058.1 - 0.029 14.1 0.0 0.23 11.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF938) KilA-N PF04383.13 EAX75059.1 - 4.2e-31 107.1 0.4 8.2e-31 106.2 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX75060.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75060.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75060.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75060.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX75060.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX75060.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX75061.1 - 1.3e-25 89.4 1.0 2.3e-25 88.6 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75061.1 - 0.0064 17.1 0.1 0.017 15.8 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family FPN1 PF06963.12 EAX75061.1 - 0.32 9.5 0.1 0.39 9.2 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4116 PF13475.6 EAX75063.1 - 0.016 14.9 0.3 0.08 12.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX75063.1 - 0.07 12.1 0.7 0.1 11.6 0.3 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Transposase_24 PF03004.14 EAX75063.1 - 0.35 11.0 4.8 1.2 9.2 3.0 2.3 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) TbpB_A PF17484.2 EAX75063.1 - 2.9 8.6 7.1 1.5 9.6 4.4 1.7 1 1 1 2 2 2 0 N-Lobe handle Tf-binding protein B Pox_A32 PF04665.12 EAX75065.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75065.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75065.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75065.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75066.1 - 5.9e-40 137.2 4.9 8.1e-40 136.8 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX75066.1 - 0.27 11.6 2.3 1.2 9.5 1.3 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain KilA-N PF04383.13 EAX75067.1 - 4.1e-40 136.1 1.0 6.3e-40 135.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75067.1 - 0.023 15.3 0.2 0.055 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family PSP PF04046.16 EAX75068.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX75069.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX75069.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX75071.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75071.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX75071.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX75071.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75071.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX75071.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF3839 PF12943.7 EAX75072.1 - 8.9e-143 473.9 9.9 1e-142 473.7 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75072.1 - 0.013 15.7 0.6 0.89 9.9 0.1 2.9 3 0 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX75072.1 - 0.025 14.4 0.6 0.061 13.2 0.5 1.7 1 1 0 1 1 1 0 Nucleotidyltransferase DUF5398 PF17376.2 EAX75072.1 - 0.14 12.8 2.7 0.8 10.4 0.0 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX75073.1 - 9.9e-43 144.5 0.5 1.6e-42 143.9 0.0 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75073.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) MPS2 PF17060.5 EAX75073.1 - 0.025 13.9 0.8 0.77 9.0 0.2 2.0 2 0 0 2 2 2 0 Monopolar spindle protein 2 Cep57_MT_bd PF06657.13 EAX75073.1 - 0.23 11.9 3.6 1.1 9.7 2.6 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 T5orf172 PF10544.9 EAX75074.1 - 4.5e-07 30.4 0.3 8.9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX75074.1 - 0.12 13.1 0.5 0.3 11.8 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4107 PF13389.6 EAX75076.1 - 4.4e-72 241.5 3.7 5.7e-72 241.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX75076.1 - 0.0041 17.5 0.1 0.0096 16.3 0.1 1.6 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta UPF0175 PF03683.13 EAX75077.1 - 0.076 12.7 0.0 5.7 6.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) DUF4108 PF13390.6 EAX75080.1 - 5.6e-61 204.7 8.2 6.2e-61 204.5 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX75082.1 - 0.015 14.9 5.8 1.7 8.2 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) ESAG1 PF03238.13 EAX75082.1 - 0.03 13.8 2.9 0.61 9.5 0.2 3.2 2 1 2 4 4 4 0 ESAG protein GST_C PF00043.25 EAX75082.1 - 0.14 12.4 0.7 2.6 8.3 0.0 3.0 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF4108 PF13390.6 EAX75085.1 - 1.2e-61 206.8 6.5 1.3e-61 206.7 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HAUS-augmin3 PF14932.6 EAX75086.1 - 0.018 14.6 2.0 0.027 14.1 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 L_lactis_ph-MCP PF06673.11 EAX75086.1 - 3.5 6.5 5.2 1.2 8.0 2.1 1.7 2 0 0 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein FliD_N PF02465.18 EAX75087.1 - 0.33 11.7 5.2 0.5 11.1 5.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX75087.1 - 1.5 7.5 3.9 1.9 7.2 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YvrJ PF12841.7 EAX75088.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family DUF2897 PF11446.8 EAX75089.1 - 1.9 8.4 3.7 3.6 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75090.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX75092.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX75092.1 - 0.18 11.7 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX75093.1 - 1.8e-120 400.9 6.1 1.9e-120 400.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75093.1 - 0.094 13.2 1.8 1.2 9.6 0.8 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX75094.1 - 4.7e-138 458.4 8.3 5.5e-138 458.2 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4106 PF13388.6 EAX75095.1 - 3.2e-204 678.9 61.2 2.3e-119 399.4 23.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX75095.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Alph_Pro_TM PF09608.10 EAX75095.1 - 0.087 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) GGN PF15685.5 EAX75095.1 - 0.73 8.8 33.4 0.99 8.4 33.4 1.1 1 0 0 1 1 1 0 Gametogenetin SOG2 PF10428.9 EAX75095.1 - 0.82 8.8 10.2 1.1 8.4 10.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_B_2 PF03175.13 EAX75096.1 - 1.4e-23 83.5 11.5 9.3e-23 80.8 11.5 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral U62_UL91 PF17442.2 EAX75097.1 - 0.11 12.5 2.0 0.28 11.2 0.4 2.4 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins Herpes_UL37_2 PF07413.11 EAX75097.1 - 0.15 11.3 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Pox_D5 PF03288.16 EAX75098.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75098.1 - 0.075 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain RFX_DNA_binding PF02257.15 EAX75099.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX75099.1 - 0.00064 20.2 1.7 0.00098 19.6 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX75099.1 - 0.034 14.1 0.8 0.073 13.1 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX75100.1 - 2.8e-54 182.9 3.6 3.1e-54 182.8 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX75102.1 - 0.087 12.7 0.8 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX75103.1 - 0.025 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75103.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Spc7 PF08317.11 EAX75109.1 - 1.1 8.1 11.4 0.13 11.1 3.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EAX75109.1 - 3.9 7.3 8.8 1.2 8.9 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TetR_C_23 PF17931.1 EAX75109.1 - 4.8 7.3 5.6 18 5.4 1.3 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1493 PF07377.12 EAX75110.1 - 0.038 14.4 1.9 0.039 14.4 1.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX75111.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX75112.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75112.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX75112.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX75112.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2939 PF11159.8 EAX75113.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX75113.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX75114.1 - 0.0057 16.7 0.1 0.0074 16.3 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX75116.1 - 3.2e-06 27.1 0.5 3.2e-06 27.1 0.5 4.3 3 2 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX75116.1 - 0.054 13.1 8.1 0.15 11.7 0.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2120 PF09893.9 EAX75116.1 - 0.11 12.6 1.1 2.1 8.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1493 PF07377.12 EAX75117.1 - 0.012 16.1 0.8 0.024 15.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX75118.1 - 6.4e-15 55.0 6.3 6.4e-15 55.0 6.3 4.5 4 2 0 4 4 4 1 Phage tail repeat like Transposase_mut PF00872.18 EAX75119.1 - 0.0069 15.3 0.1 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family DUF2939 PF11159.8 EAX75120.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75120.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX75120.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX75120.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX75121.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DDE_1 PF03184.19 EAX75122.1 - 6.6e-12 45.4 0.2 1.4e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease PSP PF04046.16 EAX75123.1 - 0.15 12.0 0.3 0.15 12.0 0.3 1.9 2 1 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX75124.1 - 0.074 13.5 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX75125.1 - 1.6e-40 137.4 0.1 4.4e-40 136.0 0.1 1.8 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX75125.1 - 0.0073 16.9 0.1 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX75126.1 - 2.4e-07 30.5 1.3 2.9e-07 30.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75126.1 - 0.018 14.8 0.1 0.045 13.5 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein Zot PF05707.12 EAX75126.1 - 0.049 13.3 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX75126.1 - 0.11 12.5 0.2 1 9.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Cytadhesin_P30 PF07271.11 EAX75127.1 - 2.3 7.7 14.8 2.8 7.4 14.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 PSP PF04046.16 EAX75128.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX75129.1 - 0.058 14.0 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX75131.1 - 2.3e-05 24.8 2.6 0.00011 22.7 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75131.1 - 0.048 14.3 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX75132.1 - 1.8e-63 212.7 6.2 2e-63 212.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3417 PF11897.8 EAX75133.1 - 0.1 13.1 0.2 0.12 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAX75135.1 - 1.8e-134 446.7 12.6 2e-134 446.6 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX75135.1 - 0.35 11.5 3.3 4.5 8.0 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX75135.1 - 0.45 11.0 3.9 1.3 9.5 1.6 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX75136.1 - 1.4e-61 207.4 12.2 4.7e-60 202.4 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX75136.1 - 0.11 12.9 0.5 0.14 12.5 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX75137.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Trypan_PARP PF05887.11 EAX75138.1 - 0.077 13.0 10.9 0.12 12.3 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_D5 PF03288.16 EAX75139.1 - 0.00012 22.5 3.0 0.0007 20.0 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX75139.1 - 0.038 13.1 1.1 0.054 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX75139.1 - 0.047 14.3 0.1 0.098 13.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75139.1 - 0.061 13.3 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX75140.1 - 2.8e-55 186.2 4.5 3.1e-55 186.1 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX75140.1 - 0.092 13.0 0.1 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PTR PF12789.7 EAX75142.1 - 3.2e-27 94.4 13.4 3.2e-27 94.4 13.4 4.2 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX75142.1 - 8.7 5.9 18.4 6.3e+02 -0.2 18.4 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX75144.1 - 4.4e-41 139.2 1.9 5.3e-41 139.0 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain Trypan_PARP PF05887.11 EAX75145.1 - 0.036 14.0 11.3 0.05 13.6 11.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX75146.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX75147.1 - 1.8e-147 489.3 11.5 2.1e-147 489.1 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX75147.1 - 0.15 12.7 1.1 0.56 10.9 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX75147.1 - 2.8 8.5 5.4 1.1 9.7 0.5 2.8 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX75148.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX75149.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX75150.1 - 0.079 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Laminin_I PF06008.14 EAX75152.1 - 2.3e-09 37.4 13.8 0.0045 16.7 2.7 3.0 1 1 2 3 3 3 3 Laminin Domain I Sec34 PF04136.15 EAX75152.1 - 0.00025 21.0 31.1 0.055 13.4 5.6 3.9 1 1 4 5 5 5 5 Sec34-like family TPR_MLP1_2 PF07926.12 EAX75152.1 - 0.00064 19.8 25.4 0.0017 18.4 8.5 2.2 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein GCN5L1 PF06320.13 EAX75152.1 - 0.00087 19.4 4.0 1.5 9.0 0.4 3.5 1 1 1 3 3 3 1 GCN5-like protein 1 (GCN5L1) YabA PF06156.13 EAX75152.1 - 0.0017 19.0 5.4 1.1 9.9 0.4 3.2 1 1 1 2 2 2 1 Initiation control protein YabA UPF0449 PF15136.6 EAX75152.1 - 0.0025 18.3 15.6 0.58 10.7 2.6 3.5 1 1 2 3 3 3 3 Uncharacterised protein family UPF0449 KASH_CCD PF14662.6 EAX75152.1 - 0.0027 17.6 16.0 0.025 14.4 15.0 2.0 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX75152.1 - 0.0028 17.1 9.0 0.31 10.4 2.4 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) DUF3450 PF11932.8 EAX75152.1 - 0.0072 15.7 24.6 0.0084 15.4 7.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 EAX75152.1 - 0.013 15.6 7.8 7.1 6.9 0.1 4.2 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II Ax_dynein_light PF10211.9 EAX75152.1 - 0.013 15.4 1.7 1 9.3 0.2 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain ZapB PF06005.12 EAX75152.1 - 0.023 15.1 8.2 11 6.5 3.6 3.6 1 1 2 3 3 3 0 Cell division protein ZapB Laminin_II PF06009.12 EAX75152.1 - 0.028 14.5 16.4 0.49 10.4 4.8 2.5 1 1 1 2 2 2 0 Laminin Domain II ERM PF00769.19 EAX75152.1 - 0.03 14.1 3.9 0.41 10.4 4.0 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 EAX75152.1 - 0.031 14.5 15.7 1.3 9.2 3.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EAX75152.1 - 0.036 14.1 6.9 0.8 9.8 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 EAX75152.1 - 0.05 13.7 13.7 0.68 10.1 4.3 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EAX75152.1 - 0.1 13.1 18.3 2.9 8.4 5.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 EAX75152.1 - 0.13 12.6 13.8 1.5 9.2 2.0 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EAX75152.1 - 0.15 10.9 14.4 0.4 9.5 4.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein PI_PP_I PF18363.1 EAX75152.1 - 0.26 11.5 7.0 7.1 6.9 0.7 3.4 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain TACC_C PF05010.14 EAX75152.1 - 0.47 10.2 4.5 4.8 6.9 0.6 2.2 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF948 PF06103.11 EAX75152.1 - 0.53 10.6 6.2 5 7.4 0.5 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 EAX75152.1 - 2.3 8.0 8.0 5.4 6.9 0.3 3.6 1 1 3 4 4 4 0 Septum formation initiator TMPIT PF07851.13 EAX75152.1 - 3.4 6.8 15.0 14 4.8 8.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EAX75152.1 - 5.2 7.1 13.4 0.37 10.8 2.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRR7 PF12095.8 EAX75152.1 - 7.3 7.1 12.2 15 6.1 0.7 4.3 1 1 2 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 FUSC PF04632.12 EAX75152.1 - 7.8 4.9 21.2 14 4.0 21.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family MCU PF04678.13 EAX75152.1 - 9.3 6.3 7.0 1.6e+02 2.3 7.0 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Prominin PF05478.11 EAX75152.1 - 9.6 4.0 16.1 5.1 4.9 7.9 2.0 1 1 1 2 2 2 0 Prominin DUF4108 PF13390.6 EAX75154.1 - 1.2e-64 216.6 6.2 1.3e-64 216.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX75155.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75155.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75155.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75155.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75155.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX75155.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4841 PF16129.5 EAX75159.1 - 0.088 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DUF2897 PF11446.8 EAX75160.1 - 1.6 8.7 3.7 3.2 7.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75161.1 - 1.1e-63 213.4 5.9 1.3e-63 213.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX75162.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75162.1 - 0.069 13.8 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain TMP PF05017.14 EAX75163.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX75164.1 - 0.051 14.0 1.3 0.089 13.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX75164.1 - 0.27 11.3 3.3 5.6 7.1 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX75165.1 - 1.8e-08 34.1 1.7 2.8e-08 33.5 0.2 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX75165.1 - 1.5e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) Fer4_12 PF13353.6 EAX75165.1 - 0.036 14.3 0.2 5.6 7.2 0.2 2.7 1 1 2 3 3 3 0 4Fe-4S single cluster domain SPATA24 PF15175.6 EAX75165.1 - 0.17 11.7 3.2 0.29 11.0 3.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Tho2 PF11262.8 EAX75167.1 - 0.061 12.5 2.7 0.068 12.4 2.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TPR_22 PF18833.1 EAX75167.1 - 0.064 13.4 0.6 0.18 12.0 0.1 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Spo12 PF05032.12 EAX75167.1 - 0.11 12.4 2.2 0.11 12.4 2.2 2.6 4 0 0 4 4 4 0 Spo12 family DUF1493 PF07377.12 EAX75168.1 - 0.082 13.4 0.5 0.16 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX75169.1 - 1.7e-26 92.3 0.8 3.2e-26 91.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75169.1 - 0.071 13.7 0.0 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family DUF4108 PF13390.6 EAX75170.1 - 4.4e-58 195.3 5.0 4.9e-58 195.1 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1031 PF06275.11 EAX75171.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX75171.1 - 0.11 12.6 0.3 0.58 10.3 0.2 2.2 1 1 1 2 2 2 0 Annexin PTR PF12789.7 EAX75172.1 - 3.2e-39 132.8 16.3 2.3e-23 82.0 6.9 5.2 5 1 0 5 5 5 2 Phage tail repeat like Gly-zipper_Omp PF13488.6 EAX75173.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX75173.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75173.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Amidase02_C PF12123.8 EAX75175.1 - 0.0078 15.9 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX75176.1 - 0.03 14.8 4.9 8.7 7.5 0.2 3.3 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75177.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX75178.1 - 3.5e-155 514.5 11.0 4.4e-155 514.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2897 PF11446.8 EAX75179.1 - 0.95 9.4 3.5 1.7 8.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75180.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX75181.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX75181.1 - 0.051 13.6 0.4 0.076 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX75181.1 - 0.083 12.9 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) YmaF PF12788.7 EAX75182.1 - 0.066 13.7 1.7 2 9.0 1.6 2.0 1 1 0 1 1 1 0 YmaF family FliD_N PF02465.18 EAX75183.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX75183.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein T5orf172 PF10544.9 EAX75185.1 - 1.5e-06 28.7 0.1 3.8e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Gly-zipper_Omp PF13488.6 EAX75186.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX75186.1 - 0.28 11.5 4.8 0.41 11.0 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75186.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4795 PF16043.5 EAX75187.1 - 0.0015 18.2 0.2 0.002 17.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX75187.1 - 0.26 11.5 4.8 2.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DNA_pol_B_2 PF03175.13 EAX75190.1 - 1.6e-11 43.7 0.3 1.6e-11 43.7 0.3 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX75190.1 - 0.0097 15.3 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein PTR PF12789.7 EAX75192.1 - 5.3e-09 36.0 2.1 5.3e-09 36.0 2.1 3.0 4 0 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX75192.1 - 1.5 9.4 8.4 21 5.7 0.1 3.5 3 1 0 3 3 3 0 YmaF family T5orf172 PF10544.9 EAX75194.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX75195.1 - 9.2e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein JMY PF15871.5 EAX75197.1 - 0.041 13.2 0.6 0.059 12.7 0.6 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein YvrJ PF12841.7 EAX75198.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family HC2 PF07382.11 EAX75199.1 - 8.2e-08 32.6 16.9 1.6e-07 31.7 16.9 1.4 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX75199.1 - 1.3e-05 25.3 1.0 2.2e-05 24.5 1.0 1.4 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF840 PF05801.11 EAX75199.1 - 0.54 10.4 2.3 6 7.0 2.3 2.4 1 1 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Aurora-A_bind PF09041.10 EAX75199.1 - 3 8.0 10.4 1.8e+03 -0.9 10.4 3.4 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX75199.1 - 5.7 7.0 7.1 5.9e+02 0.5 7.1 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) DUF3839 PF12943.7 EAX75200.1 - 4.2e-157 520.8 14.1 5.2e-157 520.5 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75200.1 - 0.14 12.5 0.8 1.9 8.8 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX75200.1 - 0.94 10.0 9.2 1.8 9.1 1.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX75201.1 - 1.9e-77 260.0 6.9 2.1e-77 259.8 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ArsA_ATPase PF02374.15 EAX75201.1 - 0.0081 15.4 0.2 0.01 15.1 0.2 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase Z1 PF10593.9 EAX75201.1 - 0.016 14.7 0.3 0.018 14.5 0.3 1.1 1 0 0 1 1 1 0 Z1 domain DUF2547 PF10818.8 EAX75201.1 - 0.1 13.5 0.6 13 6.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) KELK PF15796.5 EAX75201.1 - 0.18 12.3 1.4 0.59 10.6 1.4 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX75202.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX75203.1 - 0.022 15.1 0.3 0.027 14.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4106 PF13388.6 EAX75204.1 - 9.1e-256 848.7 13.5 1.5e-255 848.0 13.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75204.1 - 0.011 16.1 0.1 0.67 10.3 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated WYL_3 PF18488.1 EAX75204.1 - 1 9.8 6.6 9.1 6.7 0.4 3.2 3 0 0 3 3 3 0 WYL domain WBS_methylT PF12589.8 EAX75204.1 - 3.8 8.3 6.0 29 5.5 2.0 2.9 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF4108 PF13390.6 EAX75205.1 - 2e-56 189.9 8.1 2.2e-56 189.8 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2247 PF10004.9 EAX75207.1 - 0.1 12.3 1.0 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF3839 PF12943.7 EAX75208.1 - 2.1e-25 89.6 4.5 3.3e-25 88.9 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tho2 PF11262.8 EAX75209.1 - 0.039 13.1 2.7 0.044 13.0 2.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX75209.1 - 6.1 6.8 12.1 0.21 11.5 2.9 2.8 4 0 0 4 4 4 0 Spo12 family PapD_N PF00345.20 EAX75210.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX75210.1 - 0.057 13.4 0.3 0.087 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX75211.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX75211.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX75212.1 - 2.3e-69 229.4 60.2 3.4e-32 110.3 18.5 4.6 3 1 2 5 5 5 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX75212.1 - 0.0048 16.8 1.8 0.0069 16.3 1.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Peptidase_C78 PF07910.13 EAX75212.1 - 0.036 13.5 2.8 1.9 7.9 0.2 3.1 1 1 3 4 4 4 0 Peptidase family C78 RACo_linker PF17650.1 EAX75212.1 - 0.042 13.7 0.3 0.95 9.4 0.3 2.5 1 1 0 1 1 1 0 RACo linker region PH_TFIIH PF08567.11 EAX75212.1 - 0.12 12.7 10.2 2.1 8.7 0.3 4.6 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain GUN4_N PF16416.5 EAX75212.1 - 0.3 11.1 4.6 7.7 6.6 0.3 3.3 2 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal AviRa PF11599.8 EAX75212.1 - 0.42 10.0 5.0 0.91 8.9 1.0 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Kelch_1 PF01344.25 EAX75213.1 - 0.00028 20.4 0.1 86 2.8 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Phage_P2_GpE PF06528.12 EAX75213.1 - 0.00032 20.2 0.1 1.5e+02 2.0 0.0 5.5 6 0 0 6 6 6 0 Phage P2 GpE DUF5438 PF17506.2 EAX75213.1 - 0.0027 18.0 12.4 22 5.5 0.0 5.4 1 1 5 6 6 6 5 Family of unknown function (DUF5438) Phage_P2_GpE PF06528.12 EAX75214.1 - 0.001 18.5 0.1 66 3.2 0.0 4.7 5 0 0 5 5 5 0 Phage P2 GpE Kelch_1 PF01344.25 EAX75214.1 - 0.0021 17.6 0.1 53 3.5 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DUF5438 PF17506.2 EAX75214.1 - 0.029 14.7 10.9 25 5.3 0.1 4.6 1 1 4 5 5 5 0 Family of unknown function (DUF5438) Imm41 PF15592.6 EAX75214.1 - 0.57 10.5 4.4 1.3 9.3 4.4 1.6 1 1 0 1 1 1 0 Immunity protein 41 DUF3839 PF12943.7 EAX75215.1 - 3.9e-151 501.3 11.2 4.5e-151 501.1 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75215.1 - 0.072 12.9 0.5 0.22 11.4 0.4 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX75215.1 - 0.18 12.1 4.7 1.3 9.3 0.0 3.2 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX75215.1 - 0.6 10.6 5.6 3.6 8.1 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX75216.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX75219.1 - 3e-07 30.2 2.9 5e-07 29.4 1.7 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75219.1 - 8.3e-06 26.1 0.2 0.00012 22.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75219.1 - 6.1e-05 22.8 0.2 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75219.1 - 0.00024 21.1 2.5 0.00058 19.9 2.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75219.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75219.1 - 0.0017 18.2 0.6 0.0032 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75219.1 - 0.0021 17.7 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75219.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX75219.1 - 0.044 14.2 0.1 0.37 11.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX75219.1 - 0.085 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX75219.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX75219.1 - 0.36 11.1 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Ank_4 PF13637.6 EAX75221.1 - 1.7e-48 162.3 7.6 1.1e-13 51.4 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX75221.1 - 1.6e-39 132.7 3.9 2.8e-07 30.7 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX75221.1 - 4.4e-39 132.9 19.4 2e-16 60.4 1.6 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX75221.1 - 8.6e-29 96.4 3.1 7.5e-05 22.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX75221.1 - 1.1e-28 98.9 3.8 6.1e-12 45.5 0.0 3.9 1 1 2 5 5 5 4 Ankyrin repeats (many copies) YcxB PF14317.6 EAX75221.1 - 1.2e-06 28.2 0.0 0.51 10.1 0.0 4.4 5 0 0 5 5 5 2 YcxB-like protein CEP44 PF15007.6 EAX75221.1 - 2.3e-06 27.8 0.3 2.9 8.1 0.0 4.0 1 1 3 4 4 4 2 Centrosomal spindle body, CEP44 Mic1 PF07035.12 EAX75221.1 - 0.00018 21.2 0.3 13 5.5 0.0 3.9 1 1 3 4 4 4 1 Colon cancer-associated protein Mic1-like MetallophosN PF16371.5 EAX75221.1 - 0.00019 21.6 0.1 0.16 12.3 0.0 3.3 1 1 3 4 4 4 3 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX75221.1 - 0.00049 20.3 0.9 12 6.3 0.0 3.9 1 1 3 4 4 4 1 Pleckstrin homology domain DUF4205 PF13898.6 EAX75221.1 - 0.011 14.6 0.6 1.3 7.9 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4205) Ribosomal_S6 PF01250.17 EAX75221.1 - 0.017 15.4 3.6 11 6.4 0.2 3.6 1 1 3 4 4 4 0 Ribosomal protein S6 TraI PF07057.11 EAX75221.1 - 0.032 14.4 2.3 1.9 8.7 0.2 2.2 1 1 1 2 2 2 0 DNA helicase TraI PrmC_N PF17827.1 EAX75221.1 - 0.16 12.6 0.2 94 3.7 0.0 3.2 1 1 2 3 3 3 0 PrmC N-terminal domain Pox_A32 PF04665.12 EAX75222.1 - 8e-08 32.0 2.0 9.8e-08 31.8 2.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75222.1 - 0.0035 17.0 0.2 0.0038 16.9 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75222.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4106 PF13388.6 EAX75223.1 - 9.6e-266 881.6 17.9 1.2e-265 881.3 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75223.1 - 0.0007 19.9 0.1 0.032 14.5 0.3 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX75223.1 - 0.027 14.3 0.2 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PapD_N PF00345.20 EAX75224.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX75225.1 - 8.3e-24 83.4 25.3 1e-22 79.9 5.0 5.3 4 1 2 6 6 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX75225.1 - 0.14 11.9 0.9 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DNA_pol_B_2 PF03175.13 EAX75227.1 - 4.9e-24 85.0 10.6 2e-23 83.0 10.5 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75227.1 - 0.099 12.6 0.0 1 9.4 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX75227.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 PSP PF04046.16 EAX75228.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX75229.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75229.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75229.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75229.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX75232.1 - 2.7e-57 192.7 4.4 3e-57 192.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX75233.1 - 0.0054 17.2 3.2 0.035 14.6 3.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX75233.1 - 0.034 13.2 1.1 0.044 12.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX75233.1 - 0.064 13.9 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX75234.1 - 3.5e-22 78.9 4.4 4.9e-22 78.4 4.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX75235.1 - 5.6e-25 87.2 6.8 5.6e-25 87.2 6.8 3.1 2 1 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX75235.1 - 0.026 14.3 1.0 0.073 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Poxvirus_B22R_C PF13168.6 EAX75235.1 - 0.059 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal GGDEF PF00990.21 EAX75236.1 - 0.032 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3464 PF11947.8 EAX75236.1 - 0.68 9.7 2.3 0.62 9.8 2.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX75237.1 - 2.1e-63 212.5 6.6 2.3e-63 212.4 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX75238.1 - 5.8e-05 23.5 2.1 0.00031 21.2 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX75239.1 - 4.6e-81 271.8 6.4 5.1e-81 271.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX75239.1 - 0.039 13.5 0.1 0.043 13.3 0.1 1.1 1 0 0 1 1 1 0 Z1 domain FliJ PF02050.16 EAX75241.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3839 PF12943.7 EAX75242.1 - 3.4e-151 501.5 13.8 4.4e-151 501.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX75242.1 - 0.013 15.9 0.8 0.81 10.1 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX75242.1 - 1.7 9.2 8.2 2.3 8.7 1.5 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glyco_hydro_30C PF17189.4 EAX75243.1 - 2.9e-08 33.8 2.1 4.4e-08 33.2 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain EpuA PF11772.8 EAX75245.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX75245.1 - 0.47 10.6 0.2 0.47 10.6 0.2 3.1 4 0 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX75245.1 - 3.3 8.1 23.9 4.8 7.6 0.5 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat Pox_D5 PF03288.16 EAX75246.1 - 9.7e-06 26.0 2.7 6.9e-05 23.3 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75246.1 - 0.059 14.0 0.1 0.11 13.2 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75246.1 - 0.12 12.3 0.3 0.23 11.4 0.2 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX75247.1 - 1.2e-52 177.7 8.0 1.3e-52 177.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PcfK PF14058.6 EAX75248.1 - 3.8 7.8 15.9 5.4 7.3 15.9 1.4 1 1 0 1 1 1 0 PcfK-like protein KilA-N PF04383.13 EAX75249.1 - 8.5e-42 141.5 0.5 1.9e-41 140.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75249.1 - 0.053 14.1 0.1 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family SHIPPO-rpt PF07004.12 EAX75251.1 - 9.1 7.4 12.9 7.9 7.6 0.4 3.9 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat DUF3839 PF12943.7 EAX75252.1 - 7.3e-80 267.9 9.6 9.2e-80 267.6 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX75252.1 - 0.084 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II NTP_transf_6 PF06042.11 EAX75252.1 - 0.13 12.1 0.8 0.52 10.2 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3420 PF11900.8 EAX75253.1 - 0.057 13.6 1.7 4.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DPM3 PF08285.11 EAX75253.1 - 0.26 11.5 0.7 2.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2362 PF10154.9 EAX75255.1 - 0.0021 17.1 4.1 0.0028 16.7 4.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) LBP_C PF17386.2 EAX75255.1 - 0.018 14.9 0.4 50 3.9 0.0 3.7 3 0 0 3 3 3 0 Lacto-N-biose phosphorylase C-terminal domain AMPKBI PF04739.15 EAX75255.1 - 2.2 8.6 23.1 8.9 6.7 0.6 4.1 1 1 2 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain KilA-N PF04383.13 EAX75256.1 - 2.6e-34 117.4 1.4 3.2e-34 117.1 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75256.1 - 0.0027 17.8 0.0 0.0081 16.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX75256.1 - 0.18 12.3 4.6 3.7 8.1 0.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4108 PF13390.6 EAX75258.1 - 3.7e-54 182.5 4.5 4.1e-54 182.4 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX75258.1 - 0.14 12.5 0.0 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Phage_fiber PF03335.13 EAX75259.1 - 6.3 7.3 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat PRA-PH PF01503.17 EAX75261.1 - 0.21 12.1 1.8 2 8.9 2.8 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase T5orf172 PF10544.9 EAX75262.1 - 2.6e-07 31.1 0.2 4.8e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX75263.1 - 9.4e-40 135.0 0.6 2.1e-39 133.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75263.1 - 0.0047 17.5 0.1 0.016 15.8 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family BAR_2 PF10455.9 EAX75264.1 - 0.064 12.4 1.0 0.074 12.2 1.0 1.0 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ResIII PF04851.15 EAX75265.1 - 2.1e-05 24.6 0.1 2.7e-05 24.3 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75265.1 - 0.00038 20.3 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75265.1 - 0.0015 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX75265.1 - 0.0017 18.7 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75265.1 - 0.0054 17.1 0.0 0.0076 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX75265.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX75265.1 - 0.065 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX75265.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX75265.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Terminase_6 PF03237.15 EAX75265.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family AAA_30 PF13604.6 EAX75265.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain SL4P PF17618.2 EAX75266.1 - 0.29 11.2 2.2 18 5.5 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4106 PF13388.6 EAX75267.1 - 5.2e-266 882.4 21.1 6.1e-266 882.2 21.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75267.1 - 0.011 16.0 0.1 0.53 10.6 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX75267.1 - 0.03 14.1 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Caprin-1_dimer PF18293.1 EAX75267.1 - 0.046 14.2 0.5 0.11 12.9 0.5 1.7 1 0 0 1 1 1 0 Caprin-1 dimerization domain PapD_N PF00345.20 EAX75269.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX75269.1 - 0.04 13.9 0.5 0.055 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX75270.1 - 3.3e-155 514.6 13.9 4.1e-155 514.3 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75270.1 - 0.15 11.9 1.1 0.62 9.9 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75270.1 - 1.8 9.1 7.4 1.8 9.1 1.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX75271.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX75271.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75271.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX75273.1 - 1.3e-62 210.0 5.8 1.4e-62 209.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX75273.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein ResIII PF04851.15 EAX75275.1 - 2.2e-05 24.6 0.1 3.1e-05 24.0 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75275.1 - 0.0005 19.9 0.0 0.00068 19.5 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75275.1 - 0.0012 18.7 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX75275.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75275.1 - 0.0042 17.4 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX75275.1 - 0.023 14.1 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX75275.1 - 0.056 13.0 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX75275.1 - 0.069 12.9 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX75275.1 - 0.098 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX75277.1 - 4.3e-07 29.7 4.5 4.6e-07 29.5 2.9 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75277.1 - 5.4e-05 23.0 0.2 0.39 10.4 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX75277.1 - 5.8e-05 23.4 0.1 0.00038 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX75277.1 - 8e-05 22.7 2.8 0.00014 21.9 2.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75277.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX75277.1 - 0.0017 18.0 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX75277.1 - 0.0018 18.1 0.4 0.0031 17.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75277.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX75277.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX75277.1 - 0.075 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX75277.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX75277.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX75277.1 - 0.44 10.8 3.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX75277.1 - 0.85 10.1 4.8 0.33 11.4 1.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PapD_N PF00345.20 EAX75279.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain RNA_polI_A34 PF08208.11 EAX75280.1 - 0.93 9.6 15.6 0.95 9.5 15.6 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2897 PF11446.8 EAX75280.1 - 4 7.4 6.9 8.3 6.4 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75281.1 - 7.3e-64 214.0 6.9 8.1e-64 213.9 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX75281.1 - 0.12 12.6 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX75282.1 - 5e-05 23.7 2.7 0.00042 20.7 2.7 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like PTR PF12789.7 EAX75283.1 - 7.1e-51 170.1 38.4 9.5e-29 99.3 11.8 4.4 4 1 0 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX75283.1 - 0.096 12.3 22.7 3.2 7.3 19.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX75283.1 - 1.3 9.4 5.1 43 4.5 0.1 3.9 2 2 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain Pox_A32 PF04665.12 EAX75284.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75284.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75284.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75284.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75285.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX75286.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75286.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75286.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75286.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX75286.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX75286.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX75286.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX75287.1 - 1.5e-56 190.3 4.7 1.6e-56 190.2 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) JMY PF15871.5 EAX75289.1 - 0.063 12.6 0.2 0.094 12.0 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Mid2 PF04478.12 EAX75290.1 - 0.00054 19.8 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX75290.1 - 0.00067 19.4 2.0 0.0011 18.7 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX75290.1 - 0.00089 19.4 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX75290.1 - 0.0032 17.8 0.4 0.064 13.6 0.3 2.3 2 1 0 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 EAX75290.1 - 0.0043 17.0 0.1 0.0077 16.1 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX75290.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX75290.1 - 0.0077 16.5 0.8 0.013 15.8 0.8 1.5 1 1 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 EAX75290.1 - 0.027 14.3 0.1 0.038 13.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX75290.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 EAX75290.1 - 0.052 14.4 0.1 0.18 12.7 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 EAX75290.1 - 0.055 11.9 0.0 0.073 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 EAX75290.1 - 0.061 12.7 3.5 0.1 12.0 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PTP_tm PF18861.1 EAX75290.1 - 0.084 12.9 1.0 0.21 11.6 0.3 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MMM1 PF10296.9 EAX75290.1 - 0.093 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ABC2_membrane_3 PF12698.7 EAX75290.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5385 PF17359.2 EAX75290.1 - 0.12 12.0 0.6 1.4 8.4 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Gemini_mov PF01708.16 EAX75290.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Otopetrin PF03189.13 EAX75290.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Otopetrin SKG6 PF08693.10 EAX75290.1 - 0.39 10.2 5.7 0.69 9.4 5.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Trypan_PARP PF05887.11 EAX75293.1 - 0.039 13.9 8.7 0.052 13.5 8.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX75294.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF2939 PF11159.8 EAX75297.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX75297.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2315 PF10231.9 EAX75298.1 - 2 8.6 8.9 0.23 11.6 4.2 1.9 2 1 0 2 2 2 0 Apoptogenic protein 1 DUF4107 PF13389.6 EAX75300.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX75300.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Armet PF10208.9 EAX75303.1 - 0.071 13.0 4.0 0.051 13.5 1.6 1.8 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding STAT_bind PF02864.15 EAX75303.1 - 0.1 13.2 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 STAT protein, DNA binding domain Chal_sti_synt_N PF00195.19 EAX75303.1 - 0.16 11.3 1.0 0.31 10.4 1.0 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX75304.1 - 1.5e-85 286.5 7.9 1.7e-85 286.3 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX75304.1 - 0.2 12.0 1.3 0.38 11.1 1.3 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit T5orf172 PF10544.9 EAX75305.1 - 6.1e-06 26.7 0.2 1.5e-05 25.4 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX75305.1 - 0.0072 16.2 1.6 0.042 13.7 0.8 2.4 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX75306.1 - 8.9e-06 26.2 0.3 2e-05 25.0 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX75307.1 - 0.068 13.6 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX75308.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX75310.1 - 2e-07 30.7 0.7 1.7e-06 27.7 0.0 2.3 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX75310.1 - 0.054 13.1 0.1 1.1 8.8 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX75310.1 - 0.087 12.7 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX75310.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX75311.1 - 5.5e-158 523.7 11.5 6.6e-158 523.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75311.1 - 0.12 12.8 5.7 1.9 9.0 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX75311.1 - 2.6 8.4 6.9 8.5 6.8 0.1 3.7 4 2 0 4 4 4 0 Tup N-terminal DUF3839 PF12943.7 EAX75313.1 - 1.2e-48 165.7 4.2 1.3e-48 165.6 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2258 PF10015.9 EAX75313.1 - 0.091 12.9 0.2 0.38 10.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) T5orf172 PF10544.9 EAX75314.1 - 2.7e-05 24.6 0.1 0.0005 20.6 0.0 2.4 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX75314.1 - 0.078 12.8 0.8 0.29 11.0 0.4 2.2 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX75314.1 - 0.078 12.5 0.5 0.25 10.8 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain T5orf172 PF10544.9 EAX75315.1 - 1.8e-06 28.4 0.3 4.2e-06 27.2 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain GPS2_interact PF15784.5 EAX75318.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75318.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX75319.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX75320.1 - 3.9e-07 29.8 2.6 7e-07 28.9 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75320.1 - 0.00065 19.5 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX75320.1 - 0.0042 17.4 0.2 0.031 14.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75320.1 - 0.0059 16.3 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ResIII PF04851.15 EAX75320.1 - 0.014 15.4 3.1 0.029 14.4 3.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX75320.1 - 0.032 14.0 0.5 0.063 13.1 0.5 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX75320.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF1827 PF08860.10 EAX75320.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX75322.1 - 1.4e-09 37.3 2.1 2.7e-09 36.4 1.1 1.7 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX75324.1 - 2.3e-29 102.6 6.9 3.3e-29 102.0 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX75325.1 - 3.4e-41 139.6 1.0 7.3e-41 138.5 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX75325.1 - 0.19 10.3 0.2 0.28 9.7 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) LOH1CR12 PF10158.9 EAX75325.1 - 0.5 10.4 3.8 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein PTR PF12789.7 EAX75326.1 - 1.2e-28 98.9 12.2 1.2e-28 98.9 12.2 3.5 4 1 1 5 5 5 1 Phage tail repeat like Imm32 PF15566.6 EAX75326.1 - 0.46 10.3 2.9 6.3 6.7 0.3 3.0 1 1 1 2 2 2 0 Immunity protein 32 YmaF PF12788.7 EAX75326.1 - 0.47 11.0 15.5 15 6.2 6.2 3.7 2 2 0 2 2 2 0 YmaF family TMP PF05017.14 EAX75328.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX75330.1 - 3.2e-53 179.5 7.8 3.6e-53 179.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX75331.1 - 3.4e-30 103.9 10.2 3.4e-30 103.9 10.2 4.4 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX75331.1 - 0.019 14.5 14.1 0.028 14.0 2.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) SHIRT PF18655.1 EAX75332.1 - 0.98 10.1 8.4 0.47 11.1 0.4 3.3 2 1 1 3 3 3 0 SHIRT domain AMPKBI PF04739.15 EAX75332.1 - 1.8 8.9 21.7 8.8 6.7 0.6 4.2 1 1 2 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain Ank_2 PF12796.7 EAX75333.1 - 0.0036 17.8 0.0 0.0089 16.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) CTD PF12815.7 EAX75333.1 - 0.5 11.0 9.0 2.4 8.8 2.7 2.7 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 SWI-SNF_Ssr4 PF08549.10 EAX75333.1 - 7.8 5.0 24.1 9.7 4.7 24.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 EAX75333.1 - 8.8 3.3 25.3 10 3.1 25.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GGDEF PF00990.21 EAX75334.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX75335.1 - 6.8e-64 214.1 7.1 7.6e-64 214.0 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HTH_Tnp_4 PF13613.6 EAX75336.1 - 1.1e-05 25.1 0.8 0.0006 19.5 0.5 2.3 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease Imm59 PF15597.6 EAX75337.1 - 0.2 12.2 3.1 0.75 10.3 0.1 2.6 2 1 0 2 2 2 0 Immunity protein 59 TPR_MLP1_2 PF07926.12 EAX75338.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX75338.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX75338.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family RNA_polI_A34 PF08208.11 EAX75339.1 - 0.039 14.0 33.1 0.049 13.7 33.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.8 EAX75339.1 - 0.072 12.0 25.4 0.085 11.8 25.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3807 PF12720.7 EAX75339.1 - 0.083 13.2 14.7 0.094 13.0 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.12 EAX75339.1 - 0.1 12.9 14.1 0.11 12.7 14.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EAX75339.1 - 0.13 12.1 17.3 0.13 12.0 17.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EAX75339.1 - 0.16 10.8 10.1 0.14 10.9 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 EAX75339.1 - 0.21 11.8 5.8 0.23 11.6 5.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF2828 PF11443.8 EAX75339.1 - 0.26 9.3 11.0 0.24 9.5 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM91_C PF14648.6 EAX75339.1 - 0.28 10.0 5.4 0.32 9.8 5.4 1.1 1 0 0 1 1 1 0 FAM91 C-terminus CPSF100_C PF13299.6 EAX75339.1 - 0.32 11.1 11.3 0.37 11.0 11.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 EAX75339.1 - 0.35 11.2 24.1 0.42 10.9 24.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 EAX75339.1 - 0.37 10.1 13.8 0.45 9.9 13.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EAX75339.1 - 0.39 9.4 7.7 0.38 9.5 7.7 1.1 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 EAX75339.1 - 0.41 10.5 27.4 0.55 10.1 27.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 EAX75339.1 - 0.43 10.0 14.4 0.5 9.8 14.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 EAX75339.1 - 0.57 9.9 8.7 0.65 9.7 8.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SET PF00856.28 EAX75339.1 - 0.58 10.5 4.4 0.69 10.3 4.4 1.1 1 0 0 1 1 1 0 SET domain DUF5427 PF10310.9 EAX75339.1 - 0.69 8.8 14.2 0.73 8.7 14.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF913 PF06025.12 EAX75339.1 - 0.78 8.6 8.5 0.9 8.5 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EAX75339.1 - 0.81 10.1 16.2 1.1 9.7 16.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 EOS1 PF12326.8 EAX75339.1 - 0.84 9.5 2.5 0.83 9.6 2.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein SAPS PF04499.15 EAX75339.1 - 0.93 8.2 9.9 0.98 8.1 9.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MCM_bind PF09739.9 EAX75339.1 - 0.97 7.8 10.6 0.97 7.8 10.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 EAX75339.1 - 1 9.1 11.3 1.2 8.9 11.3 1.1 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.7 EAX75339.1 - 1.2 7.1 7.0 1.2 7.2 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 EAX75339.1 - 1.4 9.0 4.7 1.4 8.9 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FancD2 PF14631.6 EAX75339.1 - 1.6 6.0 9.3 1.6 6.0 9.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease V_ATPase_I PF01496.19 EAX75339.1 - 1.7 6.5 9.0 1.6 6.5 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paramyxo_ncap PF00973.19 EAX75339.1 - 1.9 7.3 4.9 1.7 7.4 4.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1943 PF09172.11 EAX75339.1 - 2 7.6 10.2 2.2 7.4 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Connexin PF00029.19 EAX75339.1 - 2.1 8.0 14.7 3.2 7.5 14.7 1.3 1 0 0 1 1 1 0 Connexin eIF_4EBP PF05456.11 EAX75339.1 - 2.4 8.1 7.5 3.6 7.6 7.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Peroxin-13_N PF04088.13 EAX75339.1 - 2.4 8.4 4.3 2.6 8.3 4.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM176 PF14851.6 EAX75339.1 - 2.6 7.7 10.8 4.2 7.0 10.8 1.4 1 0 0 1 1 1 0 FAM176 family MDM10 PF12519.8 EAX75339.1 - 2.8 6.7 6.9 2.6 6.8 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RP-C_C PF11800.8 EAX75339.1 - 3 7.9 8.2 3.6 7.6 8.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3464 PF11947.8 EAX75339.1 - 3.3 7.4 19.3 5.2 6.8 19.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ALMT PF11744.8 EAX75339.1 - 3.7 6.3 7.4 4.2 6.1 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RRN3 PF05327.11 EAX75339.1 - 4 5.9 11.0 4.4 5.7 11.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sec62 PF03839.16 EAX75339.1 - 5 6.6 16.7 6.7 6.1 16.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RPA43_OB PF17875.1 EAX75339.1 - 5.1 7.7 10.0 8.4 7.0 10.0 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Tim54 PF11711.8 EAX75339.1 - 6.1 5.5 20.4 9.2 4.9 20.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CLN3 PF02487.17 EAX75339.1 - 6.7 5.6 6.6 7.8 5.4 6.6 1.1 1 0 0 1 1 1 0 CLN3 protein PPL5 PF18168.1 EAX75339.1 - 7 5.9 12.9 8.7 5.5 12.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 AIF_C PF14721.6 EAX75339.1 - 8.9 6.7 11.8 14 6.1 11.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4108 PF13390.6 EAX75340.1 - 3.6e-62 208.5 6.7 4e-62 208.4 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX75341.1 - 0.00079 19.9 0.1 0.0018 18.8 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX75341.1 - 0.015 15.2 1.0 0.056 13.3 1.0 2.0 1 1 0 1 1 1 0 KilA-N domain FRG PF08867.11 EAX75341.1 - 0.096 13.6 0.1 0.76 10.8 0.0 2.1 2 0 0 2 2 2 0 FRG domain DUF1493 PF07377.12 EAX75342.1 - 0.075 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX75343.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75344.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX75345.1 - 2.5e-22 79.4 10.9 1.5e-21 76.9 10.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX75345.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF2939 PF11159.8 EAX75346.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX75346.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX75347.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX75349.1 - 2.6e-29 102.4 6.6 4e-29 101.8 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX75349.1 - 0.055 12.6 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX75349.1 - 0.093 13.2 0.3 0.68 10.4 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB RecO_C PF02565.15 EAX75349.1 - 0.2 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal TPR_22 PF18833.1 EAX75350.1 - 0.052 13.7 0.2 0.14 12.3 0.1 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Tho2 PF11262.8 EAX75350.1 - 0.054 12.7 2.2 0.058 12.6 2.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pox_D5 PF03288.16 EAX75351.1 - 2.6e-05 24.6 2.9 0.00035 21.0 2.9 2.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX75352.1 - 1.3e-58 197.0 8.2 1.5e-58 196.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX75353.1 - 9 6.3 6.7 20 5.1 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) MG2 PF01835.19 EAX75354.1 - 1e-05 25.9 0.9 0.0043 17.5 0.1 3.3 3 1 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX75354.1 - 7.8e-05 22.9 2.6 0.022 15.0 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX75354.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain DapB_N PF01113.20 EAX75354.1 - 0.017 15.2 2.0 0.038 14.1 2.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus He_PIG PF05345.12 EAX75354.1 - 0.018 15.2 0.4 0.26 11.5 0.1 3.1 1 1 1 2 2 2 0 Putative Ig domain NPCBM_assoc PF10633.9 EAX75354.1 - 0.042 14.1 7.3 0.061 13.6 0.2 3.7 3 2 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2914 PF11141.8 EAX75354.1 - 0.044 13.5 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) PKD PF00801.20 EAX75354.1 - 0.051 13.4 0.1 0.47 10.3 0.0 2.6 2 0 0 2 2 2 0 PKD domain bMG6 PF17962.1 EAX75354.1 - 0.065 13.4 0.9 3.7 7.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 Orf78 PF06024.12 EAX75354.1 - 0.27 11.5 2.2 0.61 10.4 2.2 1.6 1 1 0 1 1 1 0 Orf78 (ac78) DUF4328 PF14219.6 EAX75354.1 - 0.3 10.6 3.2 0.15 11.6 1.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) RIFIN PF02009.16 EAX75354.1 - 0.57 10.0 6.7 0.77 9.6 6.7 1.2 1 0 0 1 1 1 0 Rifin EMP24_GP25L PF01105.24 EAX75354.1 - 0.81 9.6 6.4 12 5.8 6.4 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4711 PF15829.5 EAX75354.1 - 2.1 8.3 7.4 0.65 9.9 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) DUF3839 PF12943.7 EAX75355.1 - 1.8e-156 518.7 13.0 2.3e-156 518.4 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75355.1 - 0.53 10.8 5.1 4 7.9 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GGDEF PF00990.21 EAX75356.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX75356.1 - 9 6.3 6.6 20 5.2 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75357.1 - 1e-60 203.8 5.9 1.2e-60 203.6 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX75358.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75358.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75358.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75358.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75358.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX75358.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX75359.1 - 2.3e-63 212.4 6.4 2.6e-63 212.2 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX75362.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX75363.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX75364.1 - 0.025 15.0 2.9 11 7.2 0.2 3.0 3 0 0 3 3 3 0 TMP repeat TilS PF09179.11 EAX75366.1 - 0.048 14.1 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 TilS substrate binding domain KilA-N PF04383.13 EAX75367.1 - 3.2e-15 55.9 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX75367.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4108 PF13390.6 EAX75368.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX75370.1 - 5.6e-79 265.0 8.4 7.1e-79 264.7 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2897 PF11446.8 EAX75371.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX75372.1 - 1.9e-05 24.9 0.2 0.00016 22.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX75372.1 - 3.2e-05 24.0 4.2 6.3e-05 23.0 4.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX75372.1 - 3.2e-05 23.5 1.8 3.2e-05 23.5 1.8 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75372.1 - 3.9e-05 23.5 0.2 0.27 10.9 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX75372.1 - 0.00043 20.1 0.0 0.00083 19.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75372.1 - 0.0012 18.7 0.5 0.0025 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75372.1 - 0.0015 18.3 0.4 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75372.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX75372.1 - 0.049 13.2 0.0 0.17 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX75372.1 - 0.065 12.7 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX75372.1 - 0.072 13.5 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX75372.1 - 0.08 12.4 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX75372.1 - 0.3 11.1 2.5 1.6 8.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX75372.1 - 0.33 11.2 4.2 8.6 6.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX75373.1 - 1.8e-06 28.4 0.3 3.6e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX75374.1 - 5.9e-123 409.0 7.0 6.9e-123 408.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX75374.1 - 0.25 11.7 1.2 0.67 10.3 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF5623 PF18536.1 EAX75376.1 - 0.082 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX75376.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3781 PF12636.7 EAX75377.1 - 0.031 14.1 1.0 0.055 13.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) hEGF PF12661.7 EAX75378.1 - 2.7 8.8 5.1 7.4 7.4 5.1 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3839 PF12943.7 EAX75379.1 - 4.7e-26 91.7 4.2 6.8e-26 91.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX75380.1 - 1.5e-57 191.5 39.6 2.1e-30 104.6 13.8 5.3 2 2 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX75380.1 - 0.037 13.8 0.9 0.074 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX75381.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat JMY PF15871.5 EAX75383.1 - 0.0075 15.6 0.4 0.012 15.0 0.4 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF4107 PF13389.6 EAX75385.1 - 2.6e-09 37.4 0.4 2.6e-09 37.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2890 PF11081.8 EAX75386.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Arm-DNA-bind_5 PF17293.2 EAX75387.1 - 2.1 8.8 13.0 0.53 10.7 6.2 3.0 2 2 1 3 3 3 0 Arm DNA-binding domain DUF3839 PF12943.7 EAX75389.1 - 8.1e-135 447.9 7.4 9.1e-135 447.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75389.1 - 0.011 16.2 1.5 0.47 11.0 0.7 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Z1 PF10593.9 EAX75389.1 - 0.038 13.5 0.6 0.061 12.8 0.6 1.6 1 1 0 1 1 1 0 Z1 domain Amidase02_C PF12123.8 EAX75390.1 - 0.0078 15.9 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1031 PF06275.11 EAX75392.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF4106 PF13388.6 EAX75393.1 - 6.9e-249 826.0 19.6 8.6e-249 825.7 19.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75393.1 - 0.015 15.6 0.1 0.74 10.1 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated MRI PF15325.6 EAX75393.1 - 1.7 9.8 6.0 7.6 7.7 6.0 2.0 1 0 0 1 1 1 0 Modulator of retrovirus infection RSS_P20 PF11757.8 EAX75393.1 - 1.8 9.1 5.8 2.5 8.6 4.2 2.1 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain WBS_methylT PF12589.8 EAX75393.1 - 5.3 7.9 10.3 19 6.1 1.1 3.0 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF4106 PF13388.6 EAX75394.1 - 1.3e-204 680.1 19.3 1.3e-204 680.1 19.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX75394.1 - 0.084 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) FapA PF03961.13 EAX75394.1 - 0.23 10.1 2.3 0.39 9.3 2.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A LRR_5 PF13306.6 EAX75395.1 - 1.7e-52 176.7 34.6 9.3e-28 96.8 16.0 2.8 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX75395.1 - 2.9e-09 36.6 0.0 0.26 11.1 0.0 5.1 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EAX75395.1 - 0.0045 17.4 2.1 2.6 8.6 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF3839 PF12943.7 EAX75397.1 - 1.5e-79 266.9 10.5 1.9e-79 266.5 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX75400.1 - 1.1e-29 103.7 1.3 1.6e-29 103.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX75401.1 - 0.042 13.8 8.8 0.066 13.2 8.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX75402.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75402.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain RFX_DNA_binding PF02257.15 EAX75405.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX75405.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX75405.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4090 PF13319.6 EAX75406.1 - 8.3e-05 22.8 0.9 17 5.7 0.0 5.6 1 1 5 7 7 7 2 Protein of unknown function (DUF4090) DUF521 PF04412.13 EAX75406.1 - 0.00017 20.4 0.5 1.1 7.9 0.0 3.3 2 1 1 4 4 4 2 Protein of unknown function (DUF521) Transketolase_C PF02780.20 EAX75406.1 - 0.00033 20.5 8.4 9.3 6.1 0.2 5.6 1 1 5 6 6 6 3 Transketolase, C-terminal domain Inv-AAD PF18785.1 EAX75406.1 - 0.0017 18.2 15.6 0.14 12.0 1.5 4.6 1 1 3 5 5 5 3 Invertebrate-AID/APOBEC-deaminase AMMECR1 PF01871.17 EAX75406.1 - 2.5 7.7 19.8 19 4.8 0.2 5.5 1 1 5 6 6 6 0 AMMECR1 Mlf1IP PF10248.9 EAX75408.1 - 2.7e-09 37.2 11.0 9.7e-09 35.4 11.0 1.8 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein zf-BED PF02892.15 EAX75408.1 - 0.047 13.7 0.8 0.11 12.5 0.8 1.6 1 0 0 1 1 1 0 BED zinc finger Ribosomal_L18_c PF14204.6 EAX75408.1 - 0.077 13.9 9.0 0.3 12.0 5.9 2.4 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region TPR_MLP1_2 PF07926.12 EAX75409.1 - 0.042 13.9 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX75409.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX75409.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family CREPT PF16566.5 EAX75410.1 - 0.023 14.9 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX75410.1 - 0.11 12.7 1.9 0.14 12.4 1.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family La PF05383.17 EAX75411.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 La domain Imm70 PF15601.6 EAX75414.1 - 0.077 12.5 5.2 10 5.6 0.3 3.0 1 1 2 3 3 3 0 Immunity protein 70 DUF3447 PF11929.8 EAX75414.1 - 4 7.5 15.2 7.9 6.5 5.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) 2_5_RNA_ligase2 PF13563.6 EAX75415.1 - 0.1 12.5 0.0 6.9 6.6 0.0 2.4 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily KilA-N PF04383.13 EAX75416.1 - 1.6e-37 127.8 0.4 4.2e-37 126.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75416.1 - 0.0046 17.1 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX75417.1 - 4.1e-07 29.7 1.2 6.8e-07 29.0 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX75418.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75419.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX75420.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX75422.1 - 4.6e-21 75.2 4.6 6.5e-21 74.7 4.6 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral MULE PF10551.9 EAX75423.1 - 1.1e-11 45.0 0.1 1.7e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain Ank_2 PF12796.7 EAX75424.1 - 4.4e-38 129.7 0.1 4.3e-19 68.9 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX75424.1 - 2.4e-22 79.0 0.0 1.3e-09 38.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX75424.1 - 1.6e-18 66.5 0.0 9.5e-07 29.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX75424.1 - 2.5e-16 59.3 0.0 9.2e-06 25.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX75424.1 - 7.4e-13 47.4 0.0 0.012 16.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat DAP_B PF07930.12 EAX75424.1 - 0.021 14.8 0.2 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B SlyX PF04102.12 EAX75424.1 - 0.14 12.8 5.6 0.23 12.1 3.5 2.2 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 EAX75424.1 - 0.22 11.5 4.3 0.42 10.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2115 PF09888.9 EAX75424.1 - 0.38 11.3 8.2 0.94 10.0 4.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Fib_alpha PF08702.10 EAX75424.1 - 0.75 10.0 6.6 0.86 9.8 3.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3839 PF12943.7 EAX75426.1 - 1.8e-128 427.0 5.9 2.1e-128 426.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75426.1 - 0.043 14.3 1.8 1.3 9.6 0.8 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX75427.1 - 8.1e-60 202.3 3.8 9.3e-60 202.1 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX75427.1 - 0.14 12.8 0.8 0.57 10.8 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX75428.1 - 5.5e-156 517.2 13.1 6.8e-156 516.9 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX75428.1 - 0.032 14.7 1.3 0.24 11.9 0.2 2.1 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX75428.1 - 0.11 13.0 0.3 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX75428.1 - 0.28 11.7 7.5 1.8 9.1 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Btz PF09405.10 EAX75430.1 - 0.68 10.2 8.4 0.67 10.2 8.4 1.0 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF4108 PF13390.6 EAX75431.1 - 1.3e-53 180.7 4.9 1.5e-53 180.6 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX75431.1 - 0.088 13.1 0.1 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX75432.1 - 6e-05 23.5 2.7 0.00029 21.3 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX75432.1 - 0.034 13.2 1.2 0.049 12.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX75432.1 - 0.052 14.2 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75432.1 - 0.064 13.2 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4107 PF13389.6 EAX75433.1 - 4.7e-72 241.4 3.9 6.2e-72 241.1 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX75435.1 - 4e-34 116.8 0.1 4e-34 116.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75435.1 - 0.0054 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX75436.1 - 8.9e-07 29.4 0.2 1.8e-06 28.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX75437.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75437.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX75438.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75438.1 - 0.15 11.0 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX75440.1 - 0.097 12.5 1.2 0.23 11.3 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX75441.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75441.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75441.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75441.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PapD_N PF00345.20 EAX75443.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX75443.1 - 0.1 12.6 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX75446.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75446.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4106 PF13388.6 EAX75447.1 - 1.7e-248 824.8 18.5 2e-248 824.5 18.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75447.1 - 0.012 15.9 0.1 0.6 10.4 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated DNA_pol_B_2 PF03175.13 EAX75448.1 - 7.2e-31 107.6 12.9 3.6e-30 105.2 12.9 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75448.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Pox_A32 PF04665.12 EAX75450.1 - 3.2e-07 30.1 0.9 1.7e-06 27.7 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX75450.1 - 0.063 12.9 0.1 0.77 9.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX75450.1 - 0.065 13.1 0.3 0.12 12.2 0.3 1.5 1 1 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX75450.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4980 PF16352.5 EAX75451.1 - 0.00026 20.9 3.2 7.2 6.7 0.1 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4980) BppL_N PF18338.1 EAX75451.1 - 0.00032 20.3 0.1 24 4.9 0.0 4.5 3 0 0 3 3 3 0 Lower baseplate protein N-terminal domain Chordopox_G3 PF06129.12 EAX75451.1 - 0.0014 19.3 8.9 4.6 8.0 0.3 3.5 3 0 0 3 3 3 3 Chordopoxvirus G3 protein TQ PF18202.1 EAX75451.1 - 0.0017 18.9 27.6 1.1 9.8 4.7 3.6 1 1 2 3 3 3 3 T-Q ester bond containing domain DUF4124 PF13511.6 EAX75451.1 - 0.0034 17.7 0.4 38 4.7 0.0 4.1 4 2 0 4 4 3 0 Domain of unknown function (DUF4124) DUF3474 PF11960.8 EAX75451.1 - 0.0056 16.9 6.8 9.1 6.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) RraB PF06877.11 EAX75451.1 - 0.011 16.5 0.0 66 4.3 0.0 3.1 3 0 0 3 3 3 0 Regulator of ribonuclease activity B UL41A PF17591.2 EAX75451.1 - 0.012 15.7 0.7 50 4.1 0.0 3.3 3 0 0 3 3 3 0 Herpesvirus UL41A DUF3416 PF11896.8 EAX75451.1 - 0.015 15.6 0.0 53 4.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) DsbC_N PF10411.9 EAX75451.1 - 0.017 14.6 0.3 30 4.2 0.0 3.6 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus SPG4 PF17325.2 EAX75451.1 - 0.034 15.2 13.1 6.9 7.8 0.6 3.4 3 0 0 3 3 3 0 Stationary phase protein 4 Kunitz_legume PF00197.18 EAX75451.1 - 0.037 14.0 7.0 13 5.7 0.2 3.2 3 0 0 3 3 3 0 Trypsin and protease inhibitor MVP_shoulder PF11978.8 EAX75451.1 - 0.051 13.6 0.6 80 3.3 0.0 3.4 3 0 0 3 3 3 0 Shoulder domain Vhr1 PF04001.13 EAX75451.1 - 0.051 13.9 1.5 76 3.7 0.0 3.2 3 0 0 3 3 3 0 Transcription factor Vhr1 LOR PF04525.12 EAX75451.1 - 0.065 12.8 9.0 9 5.8 0.2 3.3 3 0 0 3 3 3 0 LURP-one-related TERB2 PF15101.6 EAX75451.1 - 0.11 12.5 4.6 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Telomere-associated protein TERB2 PQQ PF01011.21 EAX75451.1 - 0.11 12.4 4.5 58 3.9 0.1 4.1 3 0 0 3 3 3 0 PQQ enzyme repeat PRMT5_C PF17286.2 EAX75451.1 - 0.12 12.2 4.6 32 4.3 0.1 3.1 3 0 0 3 3 3 0 PRMT5 oligomerisation domain Enterotoxin_a PF01375.17 EAX75451.1 - 2.1 7.9 12.3 13 5.3 0.2 3.2 3 0 0 3 3 3 0 Heat-labile enterotoxin alpha chain bZIP_C PF12498.8 EAX75451.1 - 5.9 7.9 11.6 52 4.8 0.4 3.1 3 0 0 3 3 3 0 Basic leucine-zipper C terminal DUF3839 PF12943.7 EAX75452.1 - 2.2e-152 505.4 12.0 2.6e-152 505.1 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75452.1 - 0.18 11.7 1.7 0.58 10.0 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75452.1 - 0.23 12.0 4.1 3.2 8.3 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HNH_3 PF13392.6 EAX75454.1 - 2.2e-07 30.5 0.1 3.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF4625 PF15418.6 EAX75455.1 - 0.00071 19.8 2.5 0.55 10.5 0.6 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) DUF3858 PF12970.7 EAX75455.1 - 0.04 14.0 0.3 0.11 12.5 0.2 1.9 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) DUF1583 PF07622.11 EAX75456.1 - 0.08 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) DNA_pol_B_2 PF03175.13 EAX75457.1 - 2e-24 86.3 7.3 9.2e-24 84.1 7.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75457.1 - 0.14 12.1 0.1 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor PTR PF12789.7 EAX75459.1 - 2.6e-24 85.1 14.2 2.6e-24 85.1 14.2 4.3 4 1 0 4 4 4 2 Phage tail repeat like DUF4404 PF14357.6 EAX75459.1 - 6.6 7.4 6.1 7.1 7.3 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF257 PF03192.13 EAX75460.1 - 0.00096 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX75460.1 - 0.086 12.8 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX75461.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75461.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75461.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75461.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Amidase02_C PF12123.8 EAX75463.1 - 0.0036 17.0 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX75464.1 - 1.1e-44 150.9 0.1 1.7e-44 150.2 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX75464.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF1493 PF07377.12 EAX75465.1 - 0.018 15.5 0.7 0.036 14.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX75466.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75466.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75466.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75466.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75467.1 - 7.3e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX75467.1 - 0.073 13.2 0.1 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF4107 PF13389.6 EAX75469.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Arm-DNA-bind_5 PF17293.2 EAX75470.1 - 2.1 8.8 13.0 0.53 10.7 6.2 3.0 2 2 1 3 3 3 0 Arm DNA-binding domain PTR PF12789.7 EAX75472.1 - 4.1e-55 183.7 33.3 8.8e-31 105.8 14.3 3.6 3 1 1 4 4 4 2 Phage tail repeat like Pox_D5 PF03288.16 EAX75473.1 - 5e-06 26.9 0.4 7e-06 26.5 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75473.1 - 0.017 15.7 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75473.1 - 0.041 13.9 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX75474.1 - 4.1e-58 195.4 9.0 4.6e-58 195.2 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX75476.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX75477.1 - 1.8e-72 242.8 3.7 2.6e-72 242.3 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX75478.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75478.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75478.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75478.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX75480.1 - 0.08 13.4 0.7 0.16 12.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KilA-N PF04383.13 EAX75481.1 - 8.7e-17 61.0 0.7 2.4e-16 59.6 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75481.1 - 0.015 15.9 0.0 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX75482.1 - 1.2e-07 31.4 2.5 1.7e-07 31.0 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75482.1 - 0.0042 16.8 0.2 0.0052 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75482.1 - 0.051 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75482.1 - 0.064 13.0 0.2 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX75482.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) APG12 PF04110.13 EAX75482.1 - 0.18 12.3 2.4 0.24 11.8 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 ACP53EA PF06313.11 EAX75483.1 - 0.026 14.7 0.3 0.053 13.7 0.3 1.6 1 0 0 1 1 1 0 Drosophila ACP53EA protein BACK PF07707.15 EAX75483.1 - 0.05 13.7 0.1 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch SLM4 PF16818.5 EAX75483.1 - 0.22 11.5 7.1 0.33 10.9 2.6 2.1 2 0 0 2 2 2 0 Protein SLM4 DUF1128 PF06569.11 EAX75483.1 - 0.33 11.0 4.9 2.5 8.1 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) RNase_P_pop3 PF08228.11 EAX75484.1 - 0.053 13.6 4.4 1.3 9.1 0.6 2.2 1 1 0 2 2 2 0 RNase P subunit Pop3 Laminin_I PF06008.14 EAX75486.1 - 4.3e-05 23.4 8.6 9.6e-05 22.2 8.0 1.5 1 1 0 1 1 1 1 Laminin Domain I SNAP PF14938.6 EAX75486.1 - 0.00072 19.1 6.5 0.0011 18.5 6.5 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP KASH_CCD PF14662.6 EAX75486.1 - 0.007 16.2 7.6 0.025 14.4 7.6 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Sec34 PF04136.15 EAX75486.1 - 0.0079 16.1 13.4 0.16 11.8 3.9 2.2 1 1 1 2 2 2 2 Sec34-like family CorA PF01544.18 EAX75486.1 - 0.015 14.6 3.9 0.018 14.4 3.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 EAX75486.1 - 0.018 15.5 2.4 0.55 10.7 0.5 2.1 1 1 1 2 2 2 0 Cell division protein ZapB UPF0449 PF15136.6 EAX75486.1 - 0.022 15.2 4.8 0.77 10.3 1.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 YojJ PF10372.9 EAX75486.1 - 0.027 14.6 9.7 0.63 10.2 0.8 2.7 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus Spc7 PF08317.11 EAX75486.1 - 0.036 12.9 6.1 0.12 11.2 6.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein CheZ PF04344.13 EAX75486.1 - 0.046 13.6 6.5 0.059 13.3 6.5 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ ERM PF00769.19 EAX75486.1 - 0.051 13.4 4.4 0.076 12.8 4.4 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prominin PF05478.11 EAX75486.1 - 0.062 11.3 5.5 0.066 11.2 5.5 1.1 1 0 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 EAX75486.1 - 0.091 13.1 9.5 1.5 9.2 2.3 2.1 1 1 1 2 2 2 0 Syntaxin-like protein Prefoldin PF02996.17 EAX75486.1 - 0.13 12.2 1.3 7.1 6.6 0.1 2.4 1 1 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 EAX75486.1 - 0.16 12.6 0.6 1.4 9.6 0.6 2.1 1 1 0 1 1 1 0 Initiation control protein YabA DUF3450 PF11932.8 EAX75486.1 - 0.18 11.1 14.1 0.48 9.7 14.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 EAX75486.1 - 0.21 11.6 16.3 0.24 11.4 8.5 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 EAX75486.1 - 0.3 11.2 6.1 1.2 9.2 6.1 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 EAX75486.1 - 0.45 10.7 11.6 0.65 10.2 3.6 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 EAX75486.1 - 0.49 8.9 17.7 0.61 8.6 17.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EAX75486.1 - 0.57 9.7 12.4 0.62 9.6 12.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Serine_rich PF08824.10 EAX75486.1 - 0.69 9.9 13.3 2.6 8.0 13.3 1.8 1 1 0 1 1 1 0 Serine rich protein interaction domain Ank_2 PF12796.7 EAX75486.1 - 0.71 10.5 8.2 1.3 9.6 1.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF4618 PF15397.6 EAX75486.1 - 0.94 8.8 6.4 0.89 8.9 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) TMP_2 PF06791.13 EAX75486.1 - 1 9.0 14.8 1.6 8.4 8.1 2.1 1 1 1 2 2 2 0 Prophage tail length tape measure protein TMPIT PF07851.13 EAX75486.1 - 1.2 8.4 7.6 2.4 7.3 7.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.11 EAX75486.1 - 1.8 9.1 10.4 6.7 7.3 2.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF5082 PF16888.5 EAX75486.1 - 2.4 8.4 12.0 9.1 6.6 3.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 EAX75486.1 - 2.6 7.6 15.1 9.9 5.6 6.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EAX75486.1 - 2.8 8.1 19.7 3.7 7.7 19.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cluap1 PF10234.9 EAX75486.1 - 4.7 6.5 10.2 5.5 6.3 10.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2400 PF09674.10 EAX75487.1 - 0.013 15.5 1.1 0.016 15.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX75487.1 - 0.053 13.5 0.3 0.07 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX75488.1 - 0.011 16.1 0.3 0.013 15.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3839 PF12943.7 EAX75489.1 - 3.3e-157 521.2 14.4 4e-157 520.9 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75489.1 - 0.28 11.6 6.8 2 8.9 1.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX75489.1 - 1.2 9.7 6.9 0.44 11.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX75491.1 - 9.5e-09 35.2 12.1 2e-08 34.1 5.2 6.0 5 1 0 5 5 5 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX75491.1 - 0.0022 18.0 7.0 0.68 9.9 2.3 3.5 2 1 1 3 3 3 3 emp24/gp25L/p24 family/GOLD DUF1910 PF08928.10 EAX75491.1 - 0.04 13.9 0.9 2 8.5 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) IL2 PF00715.17 EAX75491.1 - 0.11 12.4 5.2 1.1 9.2 0.2 3.0 3 0 0 3 3 3 0 Interleukin 2 DUF3839 PF12943.7 EAX75492.1 - 2e-25 89.6 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX75492.1 - 0.14 12.6 0.7 0.6 10.6 0.1 1.9 1 1 0 2 2 2 0 Cell division protein ZapB Amidase02_C PF12123.8 EAX75495.1 - 0.0078 15.9 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase AAA_22 PF13401.6 EAX75497.1 - 3.4e-05 24.1 0.1 0.00023 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75497.1 - 7.7e-05 22.5 0.3 0.31 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75497.1 - 7.8e-05 22.7 2.8 0.00013 22.0 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75497.1 - 0.00029 20.7 0.1 0.00048 20.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75497.1 - 0.00063 19.6 0.5 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75497.1 - 0.0084 16.5 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX75497.1 - 0.059 12.8 0.1 0.087 12.3 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX75497.1 - 0.063 13.7 0.1 0.4 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX75497.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX75497.1 - 0.15 12.3 3.7 6.1 7.2 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX75497.1 - 1.1 9.7 4.7 0.44 11.0 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 DUF1493 PF07377.12 EAX75499.1 - 0.028 14.9 0.4 0.055 13.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX75499.1 - 0.25 11.4 2.2 8.4 6.5 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein KilA-N PF04383.13 EAX75500.1 - 3e-41 139.8 0.5 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75500.1 - 0.029 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) LOH1CR12 PF10158.9 EAX75500.1 - 0.58 10.2 3.0 2.3 8.3 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF3839 PF12943.7 EAX75501.1 - 1.7e-117 391.1 12.7 2.1e-117 390.8 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75501.1 - 0.11 12.9 2.5 1.7 9.2 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX75501.1 - 0.12 13.0 0.7 0.24 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX75501.1 - 0.12 12.2 0.6 0.64 9.9 0.6 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX75502.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75502.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75502.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75502.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75502.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX75502.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX75503.1 - 2.9e-17 62.5 0.1 5.6e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX75504.1 - 3.9e-78 262.2 11.5 5.1e-78 261.9 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX75504.1 - 0.0086 16.1 0.6 2.6 8.1 0.0 2.3 1 1 0 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NTP_transf_6 PF06042.11 EAX75504.1 - 0.13 12.2 1.6 0.39 10.6 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX75505.1 - 1.8e-80 269.9 11.5 2.3e-80 269.5 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX75505.1 - 0.041 14.3 0.5 0.046 14.2 0.5 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX75505.1 - 0.1 13.1 0.4 0.18 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX75506.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX75506.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Trypan_PARP PF05887.11 EAX75508.1 - 0.0052 16.8 8.7 0.0081 16.1 8.7 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Collagen_bind_2 PF12904.7 EAX75511.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF3839 PF12943.7 EAX75513.1 - 4e-157 520.9 14.1 5e-157 520.6 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX75513.1 - 0.2 12.2 4.7 0.37 11.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX75513.1 - 0.49 10.9 5.1 5.2 7.6 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX75515.1 - 1.2e-118 394.9 11.4 1.5e-118 394.6 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX75515.1 - 0.029 14.6 0.1 0.074 13.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX75515.1 - 0.19 11.6 1.2 0.6 10.0 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75515.1 - 0.21 12.1 3.2 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX75516.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain KilA-N PF04383.13 EAX75517.1 - 8.7e-27 93.2 1.6 1e-26 93.0 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX75517.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX75519.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75519.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75519.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75519.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75520.1 - 7.3e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX75520.1 - 0.16 12.4 0.9 0.69 10.4 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF3839 PF12943.7 EAX75522.1 - 7.8e-79 264.5 9.6 1e-78 264.1 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX75523.1 - 1.3e-35 121.6 0.6 2.8e-35 120.6 0.0 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75523.1 - 0.0035 17.9 0.0 0.008 16.8 0.0 1.6 1 0 0 1 1 1 1 Parathyroid hormone family PapD_N PF00345.20 EAX75524.1 - 0.03 14.2 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75524.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX75527.1 - 4e-31 107.2 0.6 9.2e-31 106.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX75529.1 - 1.3e-55 185.3 30.8 2.4e-34 117.2 15.3 3.7 3 1 1 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX75529.1 - 0.26 11.8 17.3 10 6.7 9.0 3.7 2 2 0 3 3 3 0 YmaF family PTR PF12789.7 EAX75530.1 - 1e-27 96.0 12.2 1e-27 96.0 12.2 2.8 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX75530.1 - 0.28 10.7 7.0 8.1 6.0 7.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX75531.1 - 2.4e-05 24.3 0.6 2.4e-05 24.3 0.6 3.7 4 1 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX75531.1 - 0.0063 16.4 2.2 0.0087 15.9 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) MpPF1 PF07668.11 EAX75531.1 - 0.019 14.3 0.3 0.03 13.6 0.3 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF3417 PF11897.8 EAX75531.1 - 0.046 14.2 0.7 0.19 12.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX75531.1 - 0.07 12.1 0.5 0.12 11.4 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4795 PF16043.5 EAX75531.1 - 0.65 9.6 11.9 24 4.4 11.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4107 PF13389.6 EAX75532.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2939 PF11159.8 EAX75533.1 - 0.024 15.0 1.0 0.032 14.6 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75533.1 - 2 7.4 3.7 2.1 7.3 3.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX75533.1 - 3.4 7.7 7.0 3.9 7.5 7.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX75534.1 - 0.017 15.2 0.2 0.022 14.8 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX75534.1 - 0.085 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX75534.1 - 0.94 9.4 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX75535.1 - 1.3e-156 519.2 14.8 1.7e-156 518.9 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75535.1 - 0.59 10.6 6.7 2.3 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX75535.1 - 4 8.0 6.5 1.4 9.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX75536.1 - 3.7e-07 29.9 2.1 3.7e-07 29.9 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX75536.1 - 4.5e-05 23.2 0.2 0.43 10.3 0.1 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX75536.1 - 8.8e-05 22.8 0.2 0.00067 19.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX75536.1 - 0.00024 21.1 3.9 0.0005 20.1 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75536.1 - 0.00095 19.0 0.1 0.0018 18.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75536.1 - 0.0034 17.2 1.3 0.0071 16.2 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75536.1 - 0.0036 17.0 2.9 0.012 15.3 0.4 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75536.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX75536.1 - 0.076 13.4 0.1 0.64 10.4 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX75536.1 - 0.081 13.0 0.6 1.3 9.1 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX75536.1 - 0.083 12.5 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX75536.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF573 PF04504.14 EAX75536.1 - 0.57 10.9 12.0 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX75536.1 - 0.57 10.5 4.6 10 6.4 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX75536.1 - 2.5 8.6 5.4 0.68 10.4 0.9 2.4 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX75543.1 - 1.9e-112 374.6 8.1 2.2e-112 374.4 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX75544.1 - 1.8e-10 40.6 0.0 4.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain LRV PF01816.17 EAX75545.1 - 0.0017 18.6 27.1 36 5.1 0.1 12.9 13 2 0 13 13 13 2 Leucine rich repeat variant MULE PF10551.9 EAX75546.1 - 6.6e-05 23.2 1.9 8.5e-05 22.9 0.5 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX75546.1 - 0.0081 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Pox_D5 PF03288.16 EAX75548.1 - 2.4e-05 24.7 2.3 0.00012 22.5 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75548.1 - 0.012 16.3 0.1 0.024 15.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX75548.1 - 0.026 14.5 0.2 0.065 13.2 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX75549.1 - 2.2e-60 202.7 6.8 2.5e-60 202.6 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) OAD_gamma PF04277.13 EAX75550.1 - 2.9 8.5 4.1 2.8 8.6 4.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4107 PF13389.6 EAX75551.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX75552.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75553.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Methyltransf_PK PF05891.12 EAX75554.1 - 8.6e-39 133.3 0.1 9.6e-39 133.2 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EAX75554.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EAX75554.1 - 9e-05 23.1 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EAX75554.1 - 0.0013 18.2 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.12 EAX75554.1 - 0.0032 18.1 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GrpE PF01025.19 EAX75554.1 - 0.041 13.5 0.0 0.095 12.4 0.0 1.5 2 0 0 2 2 2 0 GrpE PadR PF03551.14 EAX75555.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2689 PF10894.8 EAX75557.1 - 0.0014 18.4 3.8 2.9 7.8 0.1 4.2 2 2 3 5 5 5 3 Protein of unknown function (DUF2689) MORN_2 PF07661.13 EAX75557.1 - 0.0069 16.5 0.1 68 4.2 0.0 3.9 4 0 0 4 4 4 0 MORN repeat variant BATS PF06968.13 EAX75557.1 - 0.067 13.3 0.0 20 5.4 0.0 3.1 2 2 1 3 3 3 0 Biotin and Thiamin Synthesis associated domain Autophagy_N PF03986.13 EAX75557.1 - 0.13 12.1 1.3 23 5.0 0.1 3.5 2 2 1 3 3 3 0 Autophagocytosis associated protein (Atg3), N-terminal domain KilA-N PF04383.13 EAX75558.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX75558.1 - 0.038 14.0 0.5 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX75558.1 - 0.094 12.1 0.6 0.41 10.0 0.3 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Pep1_7 PF17232.2 EAX75560.1 - 0.56 10.7 7.1 0.47 11.0 0.3 2.7 1 1 1 2 2 2 0 Elicitor peptide 1-7 TMP PF05017.14 EAX75561.1 - 0.036 14.6 4.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX75564.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75565.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX75567.1 - 7.2e-07 28.9 2.6 7.2e-07 28.9 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75567.1 - 3.3e-05 24.2 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75567.1 - 5.4e-05 23.0 0.2 0.33 10.7 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75567.1 - 0.00014 21.9 3.2 0.00031 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75567.1 - 0.00063 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75567.1 - 0.0016 18.3 0.8 0.003 17.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75567.1 - 0.0018 18.0 0.3 0.013 15.2 0.1 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75567.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX75567.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX75567.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX75567.1 - 0.11 13.0 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3839 PF12943.7 EAX75569.1 - 1.4e-153 509.3 13.3 1.7e-153 509.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75569.1 - 0.31 11.5 6.8 1.9 9.0 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX75570.1 - 4.3e-34 116.4 23.1 8.8e-31 105.8 13.6 4.3 3 2 2 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX75570.1 - 0.037 13.7 0.9 0.078 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1043 PF06295.12 EAX75571.1 - 0.051 13.6 0.4 0.064 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX75572.1 - 0.03 14.7 0.4 0.038 14.4 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX75573.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta START PF01852.19 EAX75574.1 - 1.3e-09 37.8 0.0 1.5e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 START domain DUF4539 PF15072.6 EAX75574.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF3781 PF12636.7 EAX75575.1 - 0.024 14.5 1.0 0.041 13.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX75576.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX75576.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX75576.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX75576.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF563 PF04577.14 EAX75577.1 - 1.5e-10 41.6 0.4 1.8e-10 41.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pox_A32 PF04665.12 EAX75578.1 - 8.2e-08 32.0 1.3 1e-07 31.7 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75578.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75578.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75578.1 - 0.048 13.6 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PapD_N PF00345.20 EAX75580.1 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain EMP24_GP25L PF01105.24 EAX75580.1 - 0.082 12.8 0.1 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PadR PF03551.14 EAX75580.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4107 PF13389.6 EAX75582.1 - 7.3e-65 218.1 13.8 2.1e-63 213.3 13.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX75583.1 - 9.1e-73 240.2 44.5 1e-32 111.9 13.2 5.9 3 2 3 6 6 6 3 Phage tail repeat like PH_TFIIH PF08567.11 EAX75583.1 - 5.9 7.3 10.7 97 3.4 0.5 4.9 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain PTR PF12789.7 EAX75584.1 - 2.9e-56 187.4 33.8 1.4e-33 114.8 17.7 3.6 2 1 1 3 3 3 2 Phage tail repeat like Hormone_6 PF00236.18 EAX75587.1 - 0.24 11.4 1.7 0.27 11.2 0.0 1.9 3 0 0 3 3 3 0 Glycoprotein hormone TPR_MLP1_2 PF07926.12 EAX75588.1 - 0.0055 16.8 0.3 0.0069 16.4 0.3 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX75588.1 - 0.094 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX75588.1 - 0.33 10.9 7.7 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX75590.1 - 4.8e-55 186.7 3.4 5.5e-55 186.5 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX75590.1 - 0.0088 15.6 0.1 0.01 15.4 0.1 1.0 1 0 0 1 1 1 1 Z1 domain DUF5398 PF17376.2 EAX75590.1 - 0.16 12.6 1.4 1.5 9.5 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX75591.1 - 2.2e-156 518.5 13.6 2.6e-156 518.2 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75591.1 - 0.065 13.1 0.9 0.24 11.2 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX75591.1 - 0.088 13.1 0.9 1.6 9.0 0.0 3.0 3 1 1 4 4 4 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX75591.1 - 0.093 13.2 0.3 0.72 10.3 0.1 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX75591.1 - 1.3 9.6 7.8 1.8 9.1 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX75593.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX75594.1 - 0.057 13.4 6.9 0.072 13.1 6.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75594.1 - 8.5 6.8 5.7 10 6.6 5.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PWI PF01480.17 EAX75596.1 - 0.041 14.2 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 PWI domain UPRTase PF14681.6 EAX75596.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase KilA-N PF04383.13 EAX75597.1 - 3.8e-11 42.8 0.2 7.6e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX75597.1 - 0.25 10.7 0.2 0.53 9.7 0.2 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX75598.1 - 4.7e-80 268.5 8.8 6.1e-80 268.2 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX75598.1 - 0.041 14.4 0.4 0.07 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RRM_1 PF00076.22 EAX75599.1 - 0.11 12.4 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gly-zipper_Omp PF13488.6 EAX75600.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX75600.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75600.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX75602.1 - 1.1e-24 87.3 3.5 1.7e-24 86.6 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX75602.1 - 0.0094 15.2 0.1 0.01 15.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PRD PF00874.20 EAX75602.1 - 0.04 14.2 1.3 0.11 12.8 0.1 2.1 1 1 1 2 2 2 0 PRD domain THOC7 PF05615.13 EAX75602.1 - 0.075 13.3 0.8 0.12 12.7 0.8 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 PTR PF12789.7 EAX75603.1 - 1.6e-11 44.1 18.4 2.9e-10 40.0 1.2 4.7 5 0 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX75603.1 - 0.033 13.8 8.3 0.12 12.0 8.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX75603.1 - 5.3 7.6 11.0 30 5.2 0.1 3.7 2 2 1 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX75603.1 - 5.6 7.4 23.8 4.4 7.7 1.1 4.6 4 0 0 4 4 4 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX75604.1 - 6.6e-80 268.1 11.7 8.7e-80 267.7 11.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX75604.1 - 0.068 12.7 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX75605.1 - 2.4e-05 23.9 0.3 2.8e-05 23.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75605.1 - 0.0022 17.7 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX75605.1 - 0.02 14.9 0.7 0.042 13.9 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX75605.1 - 0.022 14.5 0.1 0.06 13.1 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein Frtz PF11768.8 EAX75605.1 - 0.036 12.4 0.0 0.037 12.3 0.0 1.0 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3783 PF12646.7 EAX75605.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX75605.1 - 0.41 10.8 2.4 2.5 8.3 0.1 2.6 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Pox_A32 PF04665.12 EAX75606.1 - 0.00014 21.4 0.4 0.00014 21.4 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX75606.1 - 0.068 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX75607.1 - 2e-146 485.9 14.2 2.4e-146 485.6 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75607.1 - 0.41 11.1 4.1 1.9 9.0 0.5 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF257 PF03192.13 EAX75610.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX75610.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4107 PF13389.6 EAX75611.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX75612.1 - 2.6e-148 492.0 8.8 2.9e-148 491.9 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX75614.1 - 6.4e-07 29.1 2.6 6.4e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75614.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75614.1 - 6.9e-05 22.6 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75614.1 - 0.00012 22.2 2.9 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75614.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75614.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX75614.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX75614.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX75614.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX75614.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX75614.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX75614.1 - 0.4 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX75615.1 - 3.3e-29 101.0 0.2 3.3e-29 101.0 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX75616.1 - 6.7e-07 29.8 0.5 2.2e-06 28.1 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX75616.1 - 0.11 12.3 1.1 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX75616.1 - 0.16 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain RIC3 PF15361.6 EAX75617.1 - 0.034 14.6 2.0 0.033 14.6 2.0 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GPS2_interact PF15784.5 EAX75617.1 - 0.037 14.5 1.2 0.048 14.1 1.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX75618.1 - 6.1e-08 32.4 1.2 7.5e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75618.1 - 0.005 16.5 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75618.1 - 0.051 13.3 0.1 0.091 12.5 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75618.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2939 PF11159.8 EAX75620.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX75621.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX75622.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX75623.1 - 0.029 14.8 1.1 0.051 14.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) DUF257 PF03192.13 EAX75624.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX75624.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3839 PF12943.7 EAX75625.1 - 2.1e-73 246.8 9.3 2.7e-73 246.4 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75625.1 - 0.047 14.0 0.5 0.12 12.7 0.1 1.9 2 1 1 3 3 3 0 Rx N-terminal domain GalP_UDP_transf PF01087.22 EAX75625.1 - 0.3 11.5 1.8 1.5 9.2 1.5 2.0 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX75626.1 - 4.3e-136 452.0 8.9 5e-136 451.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX75626.1 - 0.088 13.4 2.3 0.67 10.6 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Trypan_PARP PF05887.11 EAX75628.1 - 0.032 14.2 9.8 0.044 13.8 9.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX75631.1 - 4.3e-57 193.3 3.6 4.9e-57 193.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX75631.1 - 0.028 13.9 0.3 0.033 13.7 0.3 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX75631.1 - 0.21 12.2 1.8 1.4 9.6 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX75632.1 - 1e-42 144.5 0.6 2.2e-42 143.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75632.1 - 0.011 16.3 0.2 0.04 14.5 0.0 2.1 2 1 0 2 2 2 0 Parathyroid hormone family PTR PF12789.7 EAX75633.1 - 3.1e-23 81.6 8.5 3.1e-23 81.6 8.5 3.6 2 1 2 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX75633.1 - 0.013 15.2 0.6 0.032 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX75634.1 - 0.073 13.5 0.7 0.15 12.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX75635.1 - 0.061 13.8 1.4 0.074 13.5 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX75636.1 - 6.3e-54 179.9 36.7 5.3e-35 119.3 16.2 4.4 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX75636.1 - 0.068 12.9 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX75637.1 - 6.3e-126 418.7 6.8 7.1e-126 418.6 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75637.1 - 0.1 12.9 0.6 3.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX75637.1 - 0.1 13.0 1.5 1.2 9.6 0.8 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX75638.1 - 6.5e-24 83.8 12.2 6.5e-24 83.8 12.2 4.1 3 1 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX75638.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX75639.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75639.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX75639.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX75639.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75639.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX75639.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF4107 PF13389.6 EAX75640.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) SRP68 PF16969.5 EAX75641.1 - 1.9e-09 37.1 0.0 2.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 GPS2_interact PF15784.5 EAX75643.1 - 0.06 13.8 2.3 0.082 13.4 2.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75643.1 - 0.076 12.0 0.1 0.077 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX75644.1 - 0.022 14.6 1.0 0.034 14.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX75645.1 - 2.3e-108 361.2 6.6 2.7e-108 361.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75645.1 - 0.045 14.2 1.4 0.098 13.1 0.9 1.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX75645.1 - 0.11 13.1 2.6 0.24 12.0 0.1 2.6 1 1 1 3 3 3 0 Family of unknown function (DUF5398) TPR_MLP1_2 PF07926.12 EAX75648.1 - 0.0017 18.4 0.1 0.0021 18.1 0.1 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX75648.1 - 0.13 12.2 5.7 0.16 11.9 2.9 2.3 2 1 0 2 2 2 0 Spo12 family Meiosis_expr PF15163.6 EAX75649.1 - 0.0092 16.6 1.3 0.012 16.3 0.5 1.6 2 0 0 2 2 2 1 Meiosis-expressed Spo12 PF05032.12 EAX75649.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family T5orf172 PF10544.9 EAX75650.1 - 5.2e-07 30.1 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX75650.1 - 0.058 13.2 1.4 0.31 10.9 0.3 2.5 2 2 0 2 2 2 0 KilA-N domain PTR PF12789.7 EAX75651.1 - 7.1e-17 61.2 2.8 7.1e-17 61.2 2.8 1.9 2 0 0 2 2 2 1 Phage tail repeat like DUF4107 PF13389.6 EAX75652.1 - 3.1e-67 225.8 10.9 1.6e-66 223.4 10.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX75653.1 - 0.036 14.5 0.4 0.068 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX75653.1 - 0.38 10.8 3.4 8.9 6.4 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PRA-PH PF01503.17 EAX75654.1 - 0.27 11.7 1.9 2 8.9 2.8 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Ank_2 PF12796.7 EAX75655.1 - 1.2e-07 32.2 0.1 3.6e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX75655.1 - 1.6e-06 28.0 1.2 0.0081 16.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX75655.1 - 0.0013 19.0 0.3 0.2 12.0 0.0 3.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX75655.1 - 0.0013 19.1 0.2 1.1 9.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX75655.1 - 0.0034 17.9 0.4 0.77 10.4 0.4 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) CTD PF12815.7 EAX75655.1 - 0.1 13.2 8.4 2.7 8.6 1.9 2.8 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 PapD_N PF00345.20 EAX75658.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75658.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mito_fiss_reg PF05308.11 EAX75660.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX75660.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX75661.1 - 4.5e-148 491.3 17.0 5.6e-148 490.9 17.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX75661.1 - 0.17 11.4 1.0 0.52 9.8 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 Glu-tRNAGln PF02686.15 EAX75661.1 - 0.71 10.2 3.9 0.86 9.9 0.5 2.6 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX75661.1 - 0.97 9.9 8.9 2.4 8.7 1.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX75661.1 - 1.2 9.4 3.9 2.6 8.4 0.1 3.1 2 2 1 3 3 3 0 Rx N-terminal domain ZapB PF06005.12 EAX75661.1 - 8.5 6.9 6.7 2.2 8.8 0.2 2.9 3 0 0 3 3 3 0 Cell division protein ZapB DUF2939 PF11159.8 EAX75662.1 - 0.028 14.8 0.4 0.038 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX75662.1 - 2.6 8.7 6.3 6.1 7.5 6.3 1.7 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX75663.1 - 0.006 16.6 0.2 0.0079 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX75664.1 - 2e-05 24.2 4.1 2.5e-05 23.8 4.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75664.1 - 0.011 15.4 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75664.1 - 0.023 14.4 0.3 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX75664.1 - 0.032 13.7 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX75664.1 - 0.04 13.7 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) RNA_helicase PF00910.22 EAX75664.1 - 0.064 13.7 0.4 0.38 11.2 0.1 2.3 1 1 0 2 2 2 0 RNA helicase DUF3783 PF12646.7 EAX75664.1 - 0.095 12.7 1.2 1 9.3 0.0 3.1 3 1 0 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX75664.1 - 0.13 12.7 2.3 0.17 12.3 1.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 TMP PF05017.14 EAX75667.1 - 0.024 15.1 3.3 11 7.3 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75668.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX75669.1 - 1.7e-06 28.5 0.4 5.5e-06 26.9 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX75669.1 - 0.026 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX75669.1 - 0.1 12.5 0.3 0.49 10.2 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain DUF4107 PF13389.6 EAX75671.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX75671.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta zinc_ribbon_10 PF10058.9 EAX75672.1 - 2.3 8.0 6.1 5.1 6.9 6.1 1.6 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Spo12 PF05032.12 EAX75674.1 - 0.55 10.2 8.3 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Imm70 PF15601.6 EAX75675.1 - 0.2 11.2 3.2 1.7 8.2 0.2 2.7 1 1 2 3 3 3 0 Immunity protein 70 Cytadhesin_P30 PF07271.11 EAX75676.1 - 8.7 5.8 18.8 11 5.5 18.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 KilA-N PF04383.13 EAX75677.1 - 5.4e-20 71.3 1.6 1.4e-17 63.6 0.1 2.8 2 1 1 3 3 3 2 KilA-N domain Parathyroid PF01279.17 EAX75677.1 - 0.0062 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Parathyroid hormone family KilA-N PF04383.13 EAX75678.1 - 1.7e-36 124.4 0.7 3.3e-36 123.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75678.1 - 0.015 15.9 0.5 0.039 14.6 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX75679.1 - 4.5e-07 30.4 0.2 9.1e-07 29.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX75680.1 - 1.3e-156 519.2 13.4 1.6e-156 518.9 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75680.1 - 5.7 7.5 8.0 1.9 9.0 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX75681.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) HAUS-augmin3 PF14932.6 EAX75682.1 - 0.0087 15.7 1.7 0.012 15.2 1.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Arm-DNA-bind_5 PF17293.2 EAX75682.1 - 9.4 6.8 14.0 2.3 8.7 7.4 3.1 2 2 0 2 2 2 0 Arm DNA-binding domain DUF3839 PF12943.7 EAX75683.1 - 4.8e-158 523.9 13.1 5.5e-158 523.7 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75683.1 - 0.16 12.4 7.5 1.8 9.1 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX75684.1 - 6.5e-157 520.2 15.2 8e-157 519.9 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX75684.1 - 0.088 12.3 0.1 0.37 10.3 0.0 2.0 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX75684.1 - 0.25 11.2 1.8 0.74 9.7 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75684.1 - 1 9.9 7.8 2.3 8.8 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX75686.1 - 5.8e-223 740.6 24.5 5.8e-223 740.6 24.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX75686.1 - 0.15 11.6 0.5 0.44 10.1 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) FapA PF03961.13 EAX75686.1 - 0.56 8.8 4.9 0.92 8.0 4.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TFIIA PF03153.13 EAX75686.1 - 1.9 8.4 32.7 0.82 9.6 19.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3839 PF12943.7 EAX75687.1 - 1.8e-156 518.8 13.5 2.2e-156 518.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX75687.1 - 0.073 13.4 0.4 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX75687.1 - 0.082 13.3 0.4 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX75687.1 - 0.083 12.7 0.8 0.27 11.1 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75687.1 - 0.62 10.6 6.9 2.1 8.9 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_D5 PF03288.16 EAX75688.1 - 0.0054 17.2 3.2 0.035 14.6 3.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX75688.1 - 0.034 13.2 1.1 0.044 12.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX75688.1 - 0.064 13.9 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DNA_pol_B_2 PF03175.13 EAX75689.1 - 1.2e-08 34.3 1.7 2.3e-08 33.4 1.7 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX75689.1 - 0.076 12.6 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX75689.1 - 0.12 12.3 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX75690.1 - 4e-23 81.4 0.3 5.9e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX75690.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin HTH_7 PF02796.15 EAX75691.1 - 0.00045 20.2 0.2 0.0008 19.4 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EAX75691.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EAX75691.1 - 0.0035 17.3 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Phage_AlpA PF05930.12 EAX75691.1 - 0.039 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Gly-zipper_Omp PF13488.6 EAX75692.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX75692.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PapD_N PF00345.20 EAX75693.1 - 0.024 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX75694.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX75694.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain KilA-N PF04383.13 EAX75695.1 - 5.7e-42 142.1 0.8 1e-41 141.3 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX75695.1 - 0.019 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX75695.1 - 0.16 10.5 0.2 0.23 10.0 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) PTR PF12789.7 EAX75696.1 - 3.3e-48 161.6 28.2 8.6e-32 109.0 14.2 4.2 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX75696.1 - 0.095 12.4 0.1 0.095 12.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Thymosin PF01290.20 EAX75697.1 - 0.029 14.1 0.0 34 4.3 0.0 4.1 3 0 0 3 3 3 0 Thymosin beta-4 family SHIPPO-rpt PF07004.12 EAX75697.1 - 7 7.7 13.6 12 7.0 1.0 4.0 3 1 1 4 4 4 0 Sperm-tail PG-rich repeat Pox_A32 PF04665.12 EAX75698.1 - 8e-07 28.8 2.4 8e-07 28.8 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75698.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75698.1 - 3.9e-05 23.4 0.3 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75698.1 - 0.00021 21.4 3.8 0.00049 20.1 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75698.1 - 0.00059 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX75698.1 - 0.0018 18.0 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX75698.1 - 0.0019 18.1 0.9 0.0039 17.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75698.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX75698.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX75698.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX75698.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX75698.1 - 0.39 11.0 4.1 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX75699.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX75699.1 - 0.18 12.1 10.8 0.25 11.6 10.8 1.3 1 1 0 1 1 1 0 PcfK-like protein FAS_N PF17828.1 EAX75700.1 - 0.021 14.8 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX75701.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75701.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX75701.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Btz PF09405.10 EAX75704.1 - 1.1 9.5 8.4 1.5 9.1 8.4 1.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF2897 PF11446.8 EAX75704.1 - 9.5 6.2 6.7 22 5.0 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75705.1 - 2.4e-58 196.1 7.7 2.7e-58 196.0 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX75706.1 - 1.7e-05 25.2 2.6 0.00011 22.6 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75706.1 - 0.085 13.5 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain TPR_MLP1_2 PF07926.12 EAX75709.1 - 0.005 16.9 0.2 0.0064 16.6 0.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX75709.1 - 0.051 13.4 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX75709.1 - 0.9 9.5 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX75710.1 - 2.3e-22 79.5 5.8 3.2e-22 79.1 5.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1493 PF07377.12 EAX75711.1 - 0.047 14.2 0.5 0.098 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Trypan_PARP PF05887.11 EAX75714.1 - 0.14 12.1 11.5 0.15 12.0 11.5 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75714.1 - 0.69 10.4 4.9 0.77 10.2 4.9 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX75715.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2897 PF11446.8 EAX75716.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75717.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX75718.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75718.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75718.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75718.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX75719.1 - 0.00019 21.2 0.2 0.00019 21.2 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75719.1 - 0.002 18.7 0.0 0.0048 17.5 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DUF3781 PF12636.7 EAX75720.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX75721.1 - 0.087 11.8 0.1 0.082 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX75724.1 - 3.4e-71 238.7 3.5 4.4e-71 238.3 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX75725.1 - 2.5e-05 24.2 0.6 2.5e-05 24.2 0.6 3.9 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX75725.1 - 0.046 13.5 4.7 0.069 13.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX75725.1 - 0.068 12.9 0.1 1.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX75725.1 - 0.087 12.4 14.7 0.041 13.5 7.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX75725.1 - 0.15 12.6 1.4 0.49 10.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX75725.1 - 0.21 10.6 1.1 0.34 9.8 1.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_A32 PF04665.12 EAX75726.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75726.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75726.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75726.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX75727.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX75727.1 - 0.064 13.4 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF2408 PF10303.9 EAX75727.1 - 0.088 13.4 0.5 0.1 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX75727.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 Trypan_PARP PF05887.11 EAX75728.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75728.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX75733.1 - 7.4e-12 45.1 1.4 1.2e-11 44.4 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX75734.1 - 1.1e-42 144.4 0.2 1.1e-42 144.4 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX75734.1 - 0.0092 16.1 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) ABC1 PF03109.16 EAX75734.1 - 0.028 14.6 1.6 0.32 11.2 0.1 2.6 1 1 1 2 2 2 0 ABC1 family Cep57_MT_bd PF06657.13 EAX75734.1 - 2.1 8.9 7.4 0.87 10.1 2.9 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 T5orf172 PF10544.9 EAX75735.1 - 1.5e-06 28.6 0.2 3e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain MULE PF10551.9 EAX75736.1 - 6.5e-11 42.5 0.3 1.2e-10 41.7 0.3 1.5 1 0 0 1 1 1 1 MULE transposase domain Amidase02_C PF12123.8 EAX75737.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX75738.1 - 3.5e-26 92.1 4.3 5.1e-26 91.6 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX75739.1 - 6.2e-08 32.4 0.7 7.6e-08 32.1 0.7 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75739.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX75739.1 - 0.026 14.3 0.0 0.064 13.0 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75739.1 - 0.071 13.1 0.3 0.65 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX75740.1 - 1.8e-45 153.4 0.1 1.8e-45 153.4 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75740.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Col_cuticle_N PF01484.17 EAX75741.1 - 0.098 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF1731 PF08338.11 EAX75742.1 - 0.14 12.0 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Collagen_bind_2 PF12904.7 EAX75743.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase GPS2_interact PF15784.5 EAX75744.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75744.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX75745.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX75745.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF5623 PF18536.1 EAX75746.1 - 0.06 13.6 0.2 0.08 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX75746.1 - 0.078 12.9 2.2 0.078 12.9 2.2 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX75747.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF2897 PF11446.8 EAX75749.1 - 4.1 7.4 5.4 7.8 6.5 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX75750.1 - 6.2e-05 23.4 2.2 0.00033 21.1 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX75750.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Spo12 PF05032.12 EAX75751.1 - 7.4 6.6 12.1 0.2 11.6 2.9 2.6 4 0 0 4 4 4 0 Spo12 family Pox_A32 PF04665.12 EAX75752.1 - 2.1e-07 30.6 2.1 3.2e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75752.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75752.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75752.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX75752.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX75752.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX75752.1 - 0.55 10.4 8.3 5.8 7.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX75753.1 - 2.5e-45 152.9 0.0 6.2e-45 151.6 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX75753.1 - 0.022 14.9 0.3 0.056 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) Noggin PF05806.12 EAX75755.1 - 0.11 12.5 1.3 0.18 11.7 1.3 1.3 1 0 0 1 1 1 0 Noggin Pox_A32 PF04665.12 EAX75756.1 - 1.9e-06 27.5 1.8 1.9e-06 27.5 1.8 2.0 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX75756.1 - 3.9e-05 24.0 0.2 0.00028 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75756.1 - 4.1e-05 23.4 0.2 0.34 10.6 0.0 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75756.1 - 0.00036 20.6 4.3 0.00049 20.1 3.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75756.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX75756.1 - 0.0058 16.3 2.7 0.018 14.7 0.1 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX75756.1 - 0.006 16.4 2.8 0.0079 16.0 0.7 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX75756.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX75756.1 - 0.084 12.4 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX75756.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX75756.1 - 0.13 12.7 0.0 0.91 10.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX75756.1 - 0.14 12.2 1.0 1.9 8.5 1.0 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX75756.1 - 1.4 9.7 11.3 0.14 12.9 2.3 3.1 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX75757.1 - 5.3e-132 438.6 8.3 6e-132 438.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75757.1 - 0.15 12.5 1.7 1.4 9.4 1.2 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX75757.1 - 0.18 12.1 2.9 1.7 9.0 0.0 2.9 2 1 1 3 3 3 0 Rx N-terminal domain PapD_N PF00345.20 EAX75758.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75758.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX75760.1 - 1.5e-05 25.5 0.3 6e-05 23.5 0.3 1.9 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX75760.1 - 0.0087 15.9 0.2 0.04 13.8 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX75761.1 - 5.1e-25 87.3 11.2 5.1e-25 87.3 11.2 4.5 5 1 0 5 5 5 1 Phage tail repeat like YmaF PF12788.7 EAX75761.1 - 0.23 12.0 18.8 0.91 10.1 0.3 4.0 2 2 0 3 3 3 0 YmaF family HIP1_clath_bdg PF16515.5 EAX75761.1 - 0.64 10.7 7.3 2.7 8.7 4.2 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pox_A32 PF04665.12 EAX75762.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein PTR PF12789.7 EAX75765.1 - 2.6e-10 40.2 33.2 1.3e-08 34.8 5.2 5.6 5 1 0 5 5 5 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX75765.1 - 0.0054 16.9 0.4 0.85 9.8 0.0 2.4 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain EpuA PF11772.8 EAX75765.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX75765.1 - 0.37 10.7 7.5 2.1 8.2 1.6 3.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD IL2 PF00715.17 EAX75765.1 - 0.54 10.2 4.1 22 5.0 0.1 3.0 2 1 1 3 3 3 0 Interleukin 2 Gly-zipper_Omp PF13488.6 EAX75767.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX75767.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX75767.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75767.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif FAS_N PF17828.1 EAX75768.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Nrf1_DNA-bind PF10491.9 EAX75769.1 - 0.0068 16.1 0.4 0.0075 16.0 0.4 1.1 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2939 PF11159.8 EAX75769.1 - 0.022 15.1 0.2 0.026 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PTR PF12789.7 EAX75771.1 - 2.1e-10 40.5 3.8 1.1e-08 35.0 0.4 4.2 5 0 0 5 5 5 2 Phage tail repeat like BRO1 PF03097.18 EAX75771.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain YmaF PF12788.7 EAX75771.1 - 1.8 9.2 10.6 32 5.1 0.1 4.1 4 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX75771.1 - 2.3 7.8 10.2 0.58 9.7 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4107 PF13389.6 EAX75772.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1269 PF06897.12 EAX75774.1 - 0.63 10.4 5.4 1.1 9.6 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TMP PF05017.14 EAX75774.1 - 3 8.9 0.2 3 8.9 0.2 3.3 4 0 0 4 4 4 0 TMP repeat DUF3839 PF12943.7 EAX75775.1 - 1.5e-143 476.5 15.5 1.9e-143 476.1 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX75775.1 - 0.031 14.7 2.8 0.083 13.3 0.4 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX75775.1 - 0.3 10.9 2.2 0.61 9.9 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX75775.1 - 0.36 11.3 6.7 1.9 9.0 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TBCC_N PF16752.5 EAX75775.1 - 0.41 11.1 4.9 0.16 12.4 1.0 2.2 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain SUKH_6 PF14568.6 EAX75777.1 - 0.038 14.4 3.0 5.2 7.5 0.3 2.9 2 2 1 3 3 3 0 SMI1-KNR4 cell-wall Pox_A32 PF04665.12 EAX75778.1 - 1.9e-07 30.8 3.1 2.9e-07 30.2 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75778.1 - 0.0034 17.1 0.2 0.0045 16.7 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX75778.1 - 0.055 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX75778.1 - 0.06 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX75778.1 - 0.43 10.8 8.5 5.8 7.1 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Autophagy_N PF03986.13 EAX75779.1 - 0.00075 19.5 1.6 1.3 8.9 0.3 3.4 1 1 2 3 3 3 2 Autophagocytosis associated protein (Atg3), N-terminal domain Aldose_epim PF01263.20 EAX75779.1 - 0.038 13.3 1.0 7.4 5.8 0.1 2.9 1 1 1 2 2 2 0 Aldose 1-epimerase DUF2846 PF11008.8 EAX75779.1 - 0.045 13.8 0.1 20 5.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2846) BATS PF06968.13 EAX75779.1 - 0.053 13.7 0.0 11 6.3 0.0 3.0 2 1 1 3 3 3 0 Biotin and Thiamin Synthesis associated domain DUF2689 PF10894.8 EAX75779.1 - 0.1 12.4 4.3 7.3 6.4 0.2 3.8 2 1 3 5 5 5 0 Protein of unknown function (DUF2689) Thymosin PF01290.20 EAX75779.1 - 0.11 12.3 0.1 1.5e+02 2.2 0.0 4.2 4 0 0 4 4 4 0 Thymosin beta-4 family Pax7 PF12360.8 EAX75779.1 - 4.6 7.5 9.5 31 4.9 0.0 4.1 3 1 1 4 4 4 0 Paired box protein 7 DUF4107 PF13389.6 EAX75780.1 - 1.9e-71 239.4 3.6 2.9e-71 238.8 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) LT-IIB PF06453.11 EAX75783.1 - 0.04 13.8 0.1 0.14 12.0 0.0 1.8 1 1 1 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF3839 PF12943.7 EAX75784.1 - 5e-99 330.7 7.4 5.7e-99 330.5 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75784.1 - 0.039 13.8 0.2 0.061 13.2 0.2 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase KilA-N PF04383.13 EAX75785.1 - 3.2e-07 30.2 0.1 5e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain Gly-zipper_Omp PF13488.6 EAX75786.1 - 0.0045 17.0 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX75786.1 - 0.062 13.2 0.5 0.12 12.3 0.5 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX75786.1 - 0.25 10.6 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX75786.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75786.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX75787.1 - 6.9e-79 262.7 11.9 7.9e-79 262.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX75789.1 - 8e-102 339.8 8.3 8.9e-102 339.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX75789.1 - 0.041 13.4 0.5 0.051 13.1 0.5 1.3 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX75789.1 - 0.1 13.1 1.0 0.29 11.6 0.4 2.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mito_fiss_reg PF05308.11 EAX75790.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX75790.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DNA_pol_B_2 PF03175.13 EAX75791.1 - 1.7e-09 37.1 0.2 3.1e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75791.1 - 0.14 12.2 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX75791.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX75794.1 - 8.3e-24 84.3 6.0 1.4e-23 83.5 6.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX75794.1 - 0.087 12.1 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX75795.1 - 2.6e-154 511.7 12.7 3.4e-154 511.3 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75795.1 - 1.1 9.7 5.3 1.9 9.0 0.7 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APC_u14 PF16635.5 EAX75795.1 - 1.3 9.6 4.1 1.4 9.5 2.1 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Trypan_PARP PF05887.11 EAX75796.1 - 0.15 12.0 12.2 0.17 11.9 12.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75796.1 - 3.6 8.1 6.3 4 7.9 6.3 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX75797.1 - 0.036 14.5 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX75799.1 - 3.9e-07 29.8 0.1 9.1e-07 28.6 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein PBAN PF05874.11 EAX75799.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) PTR PF12789.7 EAX75800.1 - 2.5e-05 24.3 0.6 2.5e-05 24.3 0.6 3.9 2 1 2 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX75800.1 - 0.016 14.9 0.1 0.074 12.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX75800.1 - 0.16 12.4 5.4 0.2 12.1 0.0 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX75800.1 - 0.18 10.7 1.9 0.28 10.1 1.9 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX75800.1 - 0.32 10.7 9.9 0.41 10.4 9.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX75800.1 - 0.83 9.2 22.0 0.089 12.4 5.8 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX75801.1 - 9.7e-64 213.6 5.8 1.1e-63 213.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX75803.1 - 3.2e-05 24.0 0.1 4.1e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75803.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX75803.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX75803.1 - 0.0019 18.5 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75803.1 - 0.0039 17.5 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX75803.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX75803.1 - 0.047 13.3 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX75803.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX75803.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX75804.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF4108 PF13390.6 EAX75806.1 - 3.2e-63 211.9 5.9 3.6e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX75807.1 - 6.6e-24 84.7 4.3 1.1e-23 84.0 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX75807.1 - 0.13 12.7 1.0 0.53 10.8 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DNA_pol_B_2 PF03175.13 EAX75808.1 - 7.8e-11 41.5 2.1 4.3e-10 39.1 2.1 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX75810.1 - 0.056 12.7 0.3 0.088 12.1 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX75811.1 - 6.1e-80 268.2 8.8 7.8e-80 267.8 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RasGAP_C PF03836.15 EAX75811.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Fez1 PF06818.15 EAX75811.1 - 0.058 13.9 0.2 0.064 13.7 0.2 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX75811.1 - 0.085 13.4 0.3 0.14 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) HAUS-augmin3 PF14932.6 EAX75812.1 - 0.024 14.2 2.5 0.034 13.7 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4107 PF13389.6 EAX75813.1 - 0.087 13.0 0.2 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX75814.1 - 1.6 7.9 9.5 1.7 7.8 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Xpo1 PF08389.12 EAX75816.1 - 3.4e-19 69.4 5.1 4.9e-19 68.9 5.1 1.2 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 EAX75816.1 - 0.0048 16.8 0.7 0.057 13.4 0.0 2.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain DUF2232 PF09991.9 EAX75816.1 - 0.005 16.1 1.0 0.21 10.7 0.2 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2232) DCB PF16213.5 EAX75816.1 - 0.017 14.8 1.1 0.026 14.2 1.1 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 NAAA-beta PF15508.6 EAX75816.1 - 0.03 14.6 0.0 3.9 7.9 0.0 2.9 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase THP2 PF09432.10 EAX75816.1 - 0.037 14.1 0.5 0.065 13.3 0.1 1.7 2 0 0 2 2 2 0 Tho complex subunit THP2 TetR_C_8 PF14278.6 EAX75816.1 - 0.096 12.8 4.3 3.6 7.7 0.5 2.8 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region Pup PF05639.11 EAX75816.1 - 0.1 13.5 1.6 0.11 13.4 0.2 1.7 2 0 0 2 2 2 0 Pup-like protein Pox_A32 PF04665.12 EAX75817.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX75817.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX75817.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX75817.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX75817.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX75817.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) KilA-N PF04383.13 EAX75820.1 - 1.1e-11 44.6 0.1 2.1e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX75822.1 - 2.3e-32 111.1 1.4 3.9e-32 110.4 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75822.1 - 0.0038 17.8 0.1 0.013 16.1 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family DUF5446 PF17522.2 EAX75823.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PapD_N PF00345.20 EAX75824.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain KilA-N PF04383.13 EAX75828.1 - 4.3e-43 145.7 0.3 1e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75828.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX75829.1 - 4.3e-06 27.2 0.2 9.5e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF2939 PF11159.8 EAX75830.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX75830.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX75831.1 - 0.016 15.2 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX75832.1 - 0.018 15.4 0.4 0.026 14.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75832.1 - 0.38 9.7 2.2 0.41 9.6 2.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX75832.1 - 2.6 8.0 4.9 2.8 7.9 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX75833.1 - 0.0096 15.9 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PadR PF03551.14 EAX75835.1 - 0.049 13.6 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Meiosis_expr PF15163.6 EAX75837.1 - 0.03 15.0 1.3 0.038 14.7 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX75837.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family GPS2_interact PF15784.5 EAX75838.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75838.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX75840.1 - 4.6e-63 211.4 6.7 5.1e-63 211.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX75840.1 - 0.058 12.5 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PTR PF12789.7 EAX75842.1 - 3.8e-31 106.9 9.6 3.8e-31 106.9 9.6 3.1 4 0 0 4 4 4 1 Phage tail repeat like DUF240 PF03086.14 EAX75842.1 - 8.9 6.3 7.8 4.8 7.1 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) TMP PF05017.14 EAX75844.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX75844.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX75846.1 - 0.028 14.9 0.6 0.058 13.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX75847.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX75847.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX75848.1 - 0.063 13.2 0.9 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP FliJ PF02050.16 EAX75849.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Presenilin PF01080.17 EAX75850.1 - 0.81 8.4 2.1 0.81 8.4 2.1 1.0 1 0 0 1 1 1 0 Presenilin DUF3839 PF12943.7 EAX75852.1 - 6.6e-128 425.2 6.3 7.6e-128 425.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX75853.1 - 2e-51 174.4 4.0 3.1e-51 173.8 4.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX75853.1 - 0.076 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX75854.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2486 PF10667.9 EAX75856.1 - 0.18 12.0 29.8 0.12 12.6 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) KilA-N PF04383.13 EAX75858.1 - 7.2e-42 141.8 0.3 1.6e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75858.1 - 0.014 16.0 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family DUF2939 PF11159.8 EAX75861.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX75861.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX75865.1 - 0.0033 17.1 0.1 0.0088 15.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase IKKbetaNEMObind PF12179.8 EAX75866.1 - 0.18 11.8 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain GPS2_interact PF15784.5 EAX75868.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75868.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF908 PF06012.12 EAX75870.1 - 0.001 18.5 1.2 0.065 12.7 0.3 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF908) Not1 PF04054.15 EAX75870.1 - 0.0018 17.3 0.5 1.2 8.0 0.0 2.0 1 1 1 2 2 2 2 CCR4-Not complex component, Not1 CLIP_SPH_mas PF18398.1 EAX75870.1 - 0.023 15.1 1.2 55 4.3 0.0 3.1 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade AAA_lid_4 PF17864.1 EAX75870.1 - 0.041 13.6 0.6 12 5.8 0.0 2.9 1 1 1 3 3 3 0 RuvB AAA lid domain RWD PF05773.22 EAX75870.1 - 0.48 10.7 3.3 12 6.2 0.6 2.9 1 1 0 2 2 2 0 RWD domain RIH_assoc PF08454.11 EAX75872.1 - 0.19 11.6 0.8 0.47 10.3 0.2 2.0 2 1 0 2 2 2 0 RyR and IP3R Homology associated Laminin_I PF06008.14 EAX75873.1 - 2e-11 44.1 25.6 0.0015 18.3 3.3 3.9 1 1 3 4 4 4 4 Laminin Domain I KASH_CCD PF14662.6 EAX75873.1 - 5.8e-08 32.8 25.2 2e-05 24.5 8.7 2.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX75873.1 - 3e-06 26.8 12.6 0.25 10.7 0.3 4.4 1 1 4 5 5 5 3 Domain of unknown function (DUF3552) ERM PF00769.19 EAX75873.1 - 2.4e-05 24.3 13.3 0.017 15.0 5.2 2.7 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Sec34 PF04136.15 EAX75873.1 - 7.2e-05 22.7 41.0 1.4 8.8 9.1 5.0 1 1 5 6 6 6 4 Sec34-like family Spc7 PF08317.11 EAX75873.1 - 0.00018 20.5 24.1 0.0017 17.3 7.4 2.6 1 1 1 2 2 2 2 Spc7 kinetochore protein ZapB PF06005.12 EAX75873.1 - 0.00028 21.3 15.2 0.56 10.7 1.3 4.6 1 1 5 6 6 6 1 Cell division protein ZapB JIP_LZII PF16471.5 EAX75873.1 - 0.00066 19.8 12.3 9.8 6.4 0.2 6.2 1 1 3 6 6 6 0 JNK-interacting protein leucine zipper II YabA PF06156.13 EAX75873.1 - 0.0013 19.4 7.8 1.1e+02 3.5 7.8 4.0 1 1 0 1 1 1 0 Initiation control protein YabA BLOC1_2 PF10046.9 EAX75873.1 - 0.0017 18.6 20.3 1.9 8.8 0.2 4.9 1 1 3 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.13 EAX75873.1 - 0.0041 17.2 12.6 4.1 7.6 0.2 4.6 1 1 4 5 5 5 1 GCN5-like protein 1 (GCN5L1) DUF3450 PF11932.8 EAX75873.1 - 0.0056 16.0 42.3 0.23 10.7 5.7 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EAX75873.1 - 0.0072 16.4 14.5 0.58 10.2 1.1 3.5 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) UPF0449 PF15136.6 EAX75873.1 - 0.01 16.3 23.7 4.6 7.8 4.4 4.7 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 BRE1 PF08647.11 EAX75873.1 - 0.01 15.9 23.7 0.18 11.9 4.9 3.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 EAX75873.1 - 0.019 15.2 27.4 0.88 9.8 4.2 3.5 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 DUF4686 PF15742.5 EAX75873.1 - 0.02 14.0 28.8 0.054 12.6 7.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Laminin_II PF06009.12 EAX75873.1 - 0.021 14.9 26.2 1.2 9.2 3.6 3.9 1 1 3 4 4 4 0 Laminin Domain II TACC_C PF05010.14 EAX75873.1 - 0.024 14.5 11.3 0.095 12.5 3.1 2.7 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APG6_N PF17675.1 EAX75873.1 - 0.029 14.9 28.1 1.8 9.1 8.8 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EAX75873.1 - 0.042 13.9 43.2 0.19 11.8 16.7 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 EAX75873.1 - 0.066 11.6 20.6 0.024 13.0 15.4 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Fib_alpha PF08702.10 EAX75873.1 - 0.086 13.0 18.9 0.68 10.1 3.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 EAX75873.1 - 0.14 11.7 26.3 8.8 5.9 10.5 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4200 PF13863.6 EAX75873.1 - 0.19 12.2 0.1 24 5.4 0.1 2.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EAX75873.1 - 0.21 11.6 18.5 0.91 9.5 6.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CheZ PF04344.13 EAX75873.1 - 0.24 11.3 20.5 1.2 9.0 3.4 3.1 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ COG7 PF10191.9 EAX75873.1 - 0.56 8.4 30.6 3.1 5.9 7.9 3.7 1 1 3 4 4 4 0 Golgi complex component 7 (COG7) DUF4201 PF13870.6 EAX75873.1 - 0.57 9.9 10.2 2.6 7.8 1.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF5082 PF16888.5 EAX75873.1 - 0.82 10.0 32.6 5.5 7.3 2.1 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 EAX75873.1 - 0.96 9.4 13.9 21 5.1 0.1 4.9 1 1 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EAX75873.1 - 1.8 8.4 14.9 21 4.9 0.5 4.8 1 1 5 6 6 6 0 Septum formation initiator Serine_rich PF08824.10 EAX75873.1 - 2.1 8.3 33.5 8.1 6.4 9.6 3.4 1 1 2 3 3 3 0 Serine rich protein interaction domain TMPIT PF07851.13 EAX75873.1 - 2.1 7.5 26.5 11 5.1 7.7 3.2 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.12 EAX75873.1 - 2.4 6.6 38.2 0.66 8.4 16.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Leu_zip PF15294.6 EAX75873.1 - 2.5 7.6 20.0 4.1 6.8 7.6 2.3 1 1 1 2 2 2 0 Leucine zipper CorA PF01544.18 EAX75873.1 - 2.5 7.3 24.6 3.8 6.7 6.0 3.3 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EAX75873.1 - 2.9 7.4 34.9 5.1 6.6 16.8 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit Prominin PF05478.11 EAX75873.1 - 4 5.3 25.9 1.8e+04 -8.3 25.9 3.0 1 1 0 1 1 0 0 Prominin Tropomyosin_1 PF12718.7 EAX75873.1 - 4.5 7.4 15.1 38 4.4 4.0 3.4 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.14 EAX75873.1 - 6 6.7 16.7 9.4 6.0 3.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMP_2 PF06791.13 EAX75873.1 - 6.2 6.4 32.0 1 9.0 7.1 3.4 1 1 2 3 3 3 0 Prophage tail length tape measure protein Pex14_N PF04695.13 EAX75874.1 - 1.9 9.1 13.1 2.3 8.8 13.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region T5orf172 PF10544.9 EAX75875.1 - 0.00072 20.1 0.7 0.0012 19.4 0.2 1.6 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX75875.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX75875.1 - 0.036 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX75875.1 - 0.049 13.2 0.4 0.081 12.4 0.4 1.3 1 0 0 1 1 1 0 Legume lectin domain DUF3839 PF12943.7 EAX75876.1 - 2.1e-117 390.8 11.5 2.7e-117 390.5 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75876.1 - 0.18 12.3 3.4 1.9 9.0 0.0 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMEM154 PF15102.6 EAX75877.1 - 3.6 7.5 7.9 4.5 7.2 7.9 1.1 1 0 0 1 1 1 0 TMEM154 protein family PTR PF12789.7 EAX75878.1 - 3.2e-05 23.9 0.6 3.2e-05 23.9 0.6 4.4 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX75878.1 - 0.042 13.7 5.6 0.061 13.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MeaB PF03308.16 EAX75878.1 - 0.17 10.8 1.7 0.27 10.2 1.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX75878.1 - 0.74 10.3 2.9 2.3 8.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) Phage_fiber PF03335.13 EAX75878.1 - 1.3 9.4 10.6 0.22 11.8 0.6 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4795 PF16043.5 EAX75878.1 - 8.3 5.9 18.1 0.51 9.9 5.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PapD_N PF00345.20 EAX75880.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4795 PF16043.5 EAX75882.1 - 0.0044 16.7 5.5 0.025 14.2 5.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX75882.1 - 9.6 6.7 8.1 21 5.6 1.8 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX75883.1 - 0.074 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX75884.1 - 1.8e-39 133.6 34.1 9e-24 83.3 6.5 5.8 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX75884.1 - 0.019 14.5 29.2 0.056 13.0 4.9 4.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) PapD_N PF00345.20 EAX75885.1 - 0.032 14.1 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX75888.1 - 1.2e-54 184.2 5.8 1.3e-54 184.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX75889.1 - 1.1e-128 427.7 7.1 1.3e-128 427.5 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75889.1 - 0.2 12.1 1.7 1.2 9.6 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX75891.1 - 1e-10 41.5 0.2 2e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Styelin PF17562.2 EAX75892.1 - 0.0093 16.3 2.3 0.014 15.7 0.5 2.1 2 0 0 2 2 2 1 Styelin dsDNA_bind PF01984.20 EAX75892.1 - 0.12 12.7 0.4 0.27 11.5 0.4 1.6 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Gly-zipper_Omp PF13488.6 EAX75893.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX75893.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX75893.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX75893.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX75893.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX75894.1 - 8.2e-56 189.2 4.2 9.4e-56 189.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX75894.1 - 0.026 14.0 0.2 0.03 13.8 0.2 1.0 1 0 0 1 1 1 0 Z1 domain MvaI_BcnI PF15515.6 EAX75894.1 - 0.05 13.4 0.9 3.3 7.5 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family DUF1493 PF07377.12 EAX75896.1 - 0.033 14.7 0.6 0.07 13.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX75897.1 - 3.4e-20 71.9 6.8 3.4e-20 71.9 6.8 3.4 3 1 1 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX75897.1 - 0.013 15.3 0.4 0.03 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2897 PF11446.8 EAX75898.1 - 1.8 8.5 5.1 3.4 7.6 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75899.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX75901.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX75902.1 - 0.038 14.0 8.0 0.05 13.6 8.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX75902.1 - 3 8.3 5.0 3.8 8.0 5.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AAA_22 PF13401.6 EAX75904.1 - 1e-05 25.8 0.1 0.0001 22.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX75904.1 - 2.9e-05 23.9 0.3 0.38 10.5 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX75904.1 - 0.0011 19.0 3.4 0.002 18.2 3.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX75904.1 - 0.0013 18.2 0.9 0.0013 18.2 0.9 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX75904.1 - 0.0019 18.0 1.0 0.0065 16.3 0.9 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX75904.1 - 0.0032 17.2 0.1 0.0051 16.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX75904.1 - 0.014 15.8 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX75904.1 - 0.04 13.5 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX75904.1 - 0.049 13.1 0.1 0.092 12.2 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein Elong_Iki1 PF10483.9 EAX75904.1 - 0.056 12.9 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX75904.1 - 0.14 12.6 0.1 0.91 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX75904.1 - 0.21 11.9 3.9 6.8 7.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX75905.1 - 1.7e-14 53.6 0.2 3.4e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX75906.1 - 1.1e-143 476.9 9.4 1.2e-143 476.7 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX75906.1 - 0.013 15.9 0.6 0.34 11.4 0.1 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PA28_beta PF02252.18 EAX75906.1 - 0.028 14.1 0.9 0.1 12.3 0.3 2.2 1 1 0 2 2 2 0 Proteasome activator pa28 beta subunit JMY PF15871.5 EAX75908.1 - 0.027 13.8 0.3 0.036 13.4 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein KilA-N PF04383.13 EAX75909.1 - 1.7e-34 118.0 0.5 3.5e-34 117.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX75909.1 - 0.012 16.3 0.1 0.031 14.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family RRP36 PF06102.12 EAX75909.1 - 0.25 11.3 6.4 0.11 12.4 2.1 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4108 PF13390.6 EAX75911.1 - 1.4e-60 203.4 9.3 1.5e-60 203.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX75911.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DNA_pol_B_2 PF03175.13 EAX75912.1 - 5.2e-17 61.9 1.9 9.6e-17 61.0 1.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX75913.1 - 5.6e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX75913.1 - 0.053 13.8 0.5 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX75913.1 - 0.17 12.3 1.2 0.42 11.1 1.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF3839 PF12943.7 EAX75914.1 - 4.7e-25 88.4 4.4 7e-25 87.9 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX75914.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4107 PF13389.6 EAX75915.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_2 PF12796.7 EAX75916.1 - 1.8e-112 368.1 12.9 1.6e-14 54.3 0.1 7.1 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX75916.1 - 2.3e-70 232.1 0.0 1.9e-12 47.4 0.0 9.7 5 4 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX75916.1 - 1.5e-59 197.2 0.0 6.1e-08 32.8 0.0 12.2 3 3 10 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX75916.1 - 3.7e-51 169.4 0.0 5.3e-05 23.5 0.0 13.0 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.6 EAX75916.1 - 4.8e-51 164.8 0.0 0.00013 22.1 0.0 13.5 11 2 2 13 13 13 10 Ankyrin repeat YfmQ PF10787.9 EAX75916.1 - 4.3e-09 36.3 1.0 0.21 11.4 0.0 5.8 2 2 3 6 6 6 3 Uncharacterised protein from bacillus cereus group CdAMP_rec PF06153.11 EAX75916.1 - 0.0001 22.5 3.4 23 5.2 0.0 5.5 3 1 2 6 6 6 0 Cyclic-di-AMP receptor HTH_22 PF13309.6 EAX75916.1 - 0.00033 20.7 5.5 11 6.2 0.1 6.7 7 3 2 9 9 9 2 HTH domain DUF5049 PF16468.5 EAX75916.1 - 0.00035 20.4 5.4 3.7 7.5 0.0 7.6 9 2 2 11 11 11 1 Domain of unknown function (DUF5049) DUF249 PF03158.13 EAX75916.1 - 0.0014 18.4 2.2 14 5.4 0.0 4.3 4 1 0 4 4 4 1 Multigene family 530 protein Decorin_bind PF02352.15 EAX75916.1 - 0.0033 17.7 2.8 1 9.7 0.1 3.1 3 0 0 3 3 3 2 Decorin binding protein L_protein_N PF15518.6 EAX75916.1 - 0.02 14.7 0.1 6.1 6.8 0.0 4.1 3 1 0 4 4 4 0 L protein N-terminus Pox_F17 PF04767.12 EAX75916.1 - 0.027 15.0 0.0 99 3.5 0.0 5.1 4 1 2 6 6 6 0 DNA-binding 11 kDa phosphoprotein La PF05383.17 EAX75917.1 - 0.039 14.0 0.1 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 La domain HD_3 PF13023.6 EAX75917.1 - 0.16 11.9 3.9 0.074 13.0 0.9 1.9 2 1 0 2 2 2 0 HD domain GPS2_interact PF15784.5 EAX75919.1 - 0.035 14.6 1.5 0.048 14.1 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75919.1 - 0.083 11.9 0.1 0.085 11.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX75920.1 - 5.4e-07 29.4 0.3 1.1e-06 28.5 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain Viral_P18 PF04521.13 EAX75921.1 - 0.0085 15.9 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein Csm2_III-A PF03750.13 EAX75922.1 - 0.02 15.7 0.8 0.024 15.4 0.8 1.1 1 0 0 1 1 1 0 Csm2 Type III-A Spo12 PF05032.12 EAX75922.1 - 0.31 11.0 7.7 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX75923.1 - 2.8e-80 269.3 9.7 3.7e-80 268.9 9.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX75923.1 - 0.056 13.7 0.1 0.13 12.5 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 DUF3839 PF12943.7 EAX75924.1 - 4.4e-80 268.6 11.6 5.8e-80 268.2 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX75924.1 - 0.035 14.6 0.3 0.04 14.4 0.3 1.2 1 0 0 1 1 1 0 Fez1 LD_cluster2 PF18163.1 EAX75924.1 - 0.063 12.8 0.7 0.24 10.9 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX75924.1 - 0.073 13.6 0.5 0.11 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX75924.1 - 0.12 12.7 1.1 0.33 11.3 0.1 2.3 3 0 0 3 3 3 0 PRD domain DNA_pol_B_2 PF03175.13 EAX75926.1 - 3.7e-25 88.7 10.3 1.5e-24 86.8 10.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75926.1 - 0.032 14.2 0.1 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX75927.1 - 1.4e-25 90.2 4.4 2.1e-25 89.6 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX75927.1 - 0.061 13.6 0.9 0.18 12.1 0.1 2.1 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX75927.1 - 0.15 12.6 1.1 0.7 10.4 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Mid2 PF04478.12 EAX75928.1 - 0.00086 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX75928.1 - 0.0011 18.7 1.9 0.0019 17.9 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX75928.1 - 0.0012 19.0 1.5 0.003 17.7 0.0 2.0 2 0 0 2 2 2 1 Podoplanin Glycophorin_A PF01102.18 EAX75928.1 - 0.0046 17.2 1.4 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 Glycophorin A Syndecan PF01034.20 EAX75928.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 EAX75928.1 - 0.011 15.6 3.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family Orf78 PF06024.12 EAX75928.1 - 0.014 15.7 2.1 0.15 12.4 0.2 2.6 3 1 0 3 3 3 0 Orf78 (ac78) DUF4448 PF14610.6 EAX75928.1 - 0.035 13.9 0.3 0.09 12.5 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX75928.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF2207 PF09972.9 EAX75928.1 - 0.068 11.9 0.4 0.21 10.3 0.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3827 PF12877.7 EAX75928.1 - 0.087 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 EAX75928.1 - 0.095 13.6 0.1 0.32 11.9 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 EAX75928.1 - 0.098 12.1 3.5 0.17 11.3 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Cortexin PF11057.8 EAX75928.1 - 0.17 11.7 0.1 0.7 9.8 0.0 2.1 3 0 0 3 3 3 0 Cortexin of kidney PsbW PF07123.12 EAX75928.1 - 0.18 11.8 0.4 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) PTP_tm PF18861.1 EAX75928.1 - 0.2 11.6 1.1 0.46 10.5 0.5 1.8 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MMM1 PF10296.9 EAX75928.1 - 0.25 10.3 1.2 0.28 10.2 0.1 1.5 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 DUF4330 PF14221.6 EAX75928.1 - 6.5 7.0 6.3 29 4.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) DUF2897 PF11446.8 EAX75929.1 - 0.79 9.6 3.2 1.4 8.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75930.1 - 9.8e-65 216.8 6.2 1.1e-64 216.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX75932.1 - 4.9 6.9 5.3 9.8 5.9 5.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX75932.1 - 10 6.1 8.3 22 5.0 8.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PapD_N PF00345.20 EAX75933.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX75933.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX75937.1 - 9e-07 29.4 0.3 1.8e-06 28.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX75937.1 - 0.13 13.0 0.4 0.32 11.7 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX75938.1 - 2.3e-42 143.4 0.4 4.8e-42 142.3 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX75939.1 - 2.1e-73 245.9 5.2 2.4e-73 245.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX75939.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase KilA-N PF04383.13 EAX75941.1 - 2.8e-41 139.9 0.6 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF2939 PF11159.8 EAX75943.1 - 0.056 13.9 0.1 0.066 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX75944.1 - 0.032 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX75944.1 - 0.092 12.7 0.4 0.14 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX75946.1 - 4.8e-07 29.5 0.1 9.1e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein PapD_N PF00345.20 EAX75947.1 - 0.037 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX75947.1 - 0.1 12.6 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX75948.1 - 0.024 15.1 0.8 0.029 14.8 0.5 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX75948.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX75948.1 - 8.1 6.4 7.2 8.6 6.3 7.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Arch_flagellin PF01917.16 EAX75949.1 - 0.13 12.5 0.2 0.24 11.6 0.1 1.5 1 1 0 1 1 1 0 Archaebacterial flagellin DUF4106 PF13388.6 EAX75950.1 - 5.4e-147 490.4 18.7 8.9e-147 489.7 18.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) WYL_3 PF18488.1 EAX75950.1 - 0.16 12.4 6.2 6.5 7.2 0.4 3.5 3 0 0 3 3 3 0 WYL domain DUF3839 PF12943.7 EAX75951.1 - 7.7e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5365 PF17326.2 EAX75952.1 - 0.024 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX75952.1 - 0.029 14.7 0.4 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain KilA-N PF04383.13 EAX75954.1 - 1.4e-30 105.4 1.1 2.4e-30 104.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75954.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF1493 PF07377.12 EAX75955.1 - 0.062 13.8 0.7 0.12 12.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX75956.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75957.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PWI PF01480.17 EAX75958.1 - 0.022 15.1 0.5 0.067 13.5 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF5365 PF17326.2 EAX75958.1 - 0.066 13.6 0.2 0.2 12.0 0.2 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5365) GPS2_interact PF15784.5 EAX75961.1 - 0.054 13.9 1.5 0.076 13.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX75961.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX75964.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat UBA PF00627.31 EAX75966.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DUF1840 PF08895.11 EAX75966.1 - 0.13 12.6 1.0 0.16 12.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DNA_pol_phi PF04931.13 EAX75966.1 - 0.2 9.7 6.3 0.24 9.5 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Polyoma_lg_T_C PF06431.11 EAX75966.1 - 0.28 10.0 2.0 0.32 9.8 2.0 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus GGDEF PF00990.21 EAX75967.1 - 0.042 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX75967.1 - 9.8 6.2 6.6 20 5.2 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX75968.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX75969.1 - 2.7e-78 262.8 9.5 3.5e-78 262.4 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX75969.1 - 0.14 12.7 1.3 0.25 11.9 1.3 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr T5orf172 PF10544.9 EAX75970.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain TMP PF05017.14 EAX75972.1 - 0.33 11.7 7.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX75973.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF641 PF04859.12 EAX75974.1 - 0.014 15.7 1.7 0.02 15.2 1.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 EAX75974.1 - 0.08 13.0 0.1 0.096 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pertus-S5-tox PF09276.10 EAX75974.1 - 0.1 12.6 0.1 0.3 11.2 0.1 1.7 1 1 0 1 1 1 0 Pertussis toxin S5 subunit bZIP_1 PF00170.21 EAX75974.1 - 0.2 11.8 8.7 0.24 11.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor Sec8_exocyst PF04048.14 EAX75974.1 - 0.21 11.5 2.5 2.3 8.1 1.5 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DHR10 PF18595.1 EAX75974.1 - 0.21 11.6 5.1 0.33 11.0 3.9 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3839 PF12943.7 EAX75975.1 - 6.9e-29 101.0 7.4 6.9e-29 101.0 7.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX75975.1 - 0.071 13.2 0.1 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers Aminotran_1_2 PF00155.21 EAX75975.1 - 0.083 12.0 0.1 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II KilA-N PF04383.13 EAX75976.1 - 6.9e-34 116.1 0.3 9.4e-34 115.6 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX75976.1 - 0.026 14.5 0.4 0.03 14.3 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAX75977.1 - 8.4e-91 303.7 9.5 9.6e-91 303.5 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX75977.1 - 0.051 14.5 0.8 5.1 8.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) KELK PF15796.5 EAX75977.1 - 0.21 12.1 2.0 0.64 10.5 2.0 1.9 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX75978.1 - 3.2e-25 88.9 9.9 1.1e-24 87.2 9.9 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX75978.1 - 0.14 12.2 0.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF4106 PF13388.6 EAX75979.1 - 1.1e-268 891.3 27.8 3.1e-268 889.8 27.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX75979.1 - 0.021 15.1 0.1 0.79 10.0 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX75979.1 - 0.025 14.4 0.2 0.062 13.1 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3839 PF12943.7 EAX75980.1 - 7.2e-154 510.2 12.2 8.4e-154 510.0 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX75982.1 - 3.1e-113 377.2 6.6 3.5e-113 377.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PSP PF04046.16 EAX75983.1 - 0.19 11.6 2.7 0.21 11.5 0.3 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX75984.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pox_D5 PF03288.16 EAX75985.1 - 7e-05 23.2 1.8 0.00036 21.0 1.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX75985.1 - 0.036 13.1 0.9 0.049 12.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX75985.1 - 0.061 14.0 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX75986.1 - 4.9e-63 211.3 6.7 5.4e-63 211.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX75988.1 - 2.5e-30 104.3 20.8 1e-29 102.3 17.0 4.0 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX75988.1 - 0.043 13.5 0.9 0.091 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX75988.1 - 5.4 7.4 6.7 15 6.0 0.2 3.2 2 1 2 4 4 4 0 TFIIH p62 subunit, N-terminal domain DNA_pol_B_2 PF03175.13 EAX75989.1 - 8.8e-09 34.7 1.2 1.6e-08 33.9 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX75989.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX75989.1 - 0.15 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PTR PF12789.7 EAX75990.1 - 7.7e-31 106.0 11.4 7.7e-31 106.0 11.4 3.1 4 0 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX75990.1 - 0.94 10.1 8.4 37 4.9 0.0 2.9 2 1 0 2 2 2 0 YmaF family DUF240 PF03086.14 EAX75990.1 - 2.9 7.8 8.4 1.9 8.4 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAX75990.1 - 5.4 6.6 13.2 2e+02 1.4 13.2 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX75991.1 - 1.3e-33 115.2 0.4 1.3e-33 115.2 0.4 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX75991.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX75991.1 - 0.05 14.1 4.3 3.2 8.3 1.5 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DDE_Tnp_ISL3 PF01610.17 EAX75992.1 - 0.0038 17.0 1.2 0.0042 16.8 0.1 1.6 2 0 0 2 2 2 1 Transposase PTR PF12789.7 EAX75993.1 - 4e-50 167.7 31.5 4.6e-34 116.3 15.2 4.1 2 2 1 3 3 3 2 Phage tail repeat like PBP5_C PF07943.13 EAX75993.1 - 0.013 15.7 0.3 0.18 12.0 0.0 2.6 2 1 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain Vps51 PF08700.11 EAX75993.1 - 0.31 11.1 4.3 20 5.3 4.3 2.7 1 1 0 1 1 1 0 Vps51/Vps67 PTR PF12789.7 EAX75994.1 - 9.5e-06 25.6 3.4 2.6e-05 24.2 0.3 2.7 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX75994.1 - 0.041 14.4 0.4 4.5 7.9 0.0 2.8 3 0 0 3 3 3 0 YmaF family Glyco_transf_36 PF06165.11 EAX75995.1 - 0.0011 18.4 1.5 0.0012 18.3 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 36 DUF2141 PF09912.9 EAX75995.1 - 0.017 15.0 0.9 0.028 14.3 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF4108 PF13390.6 EAX75996.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX75997.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX75998.1 - 2.5e-05 24.4 1.3 4.4e-05 23.5 1.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX75998.1 - 0.00029 20.7 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX75998.1 - 0.00039 20.7 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX75998.1 - 0.0013 18.6 0.1 0.0021 17.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX75998.1 - 0.0064 16.8 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX75998.1 - 0.033 13.7 0.1 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX75998.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX75998.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX75998.1 - 0.22 11.2 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX75999.1 - 1.2e-153 509.5 12.5 1.5e-153 509.2 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX75999.1 - 0.1 12.5 1.1 0.38 10.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX75999.1 - 1.4 9.3 4.2 9.2 6.6 0.0 3.4 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX75999.1 - 1.5 9.3 5.1 3.3 8.2 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX76001.1 - 1.1e-155 516.1 13.1 1.3e-155 515.9 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX76001.1 - 0.27 11.7 6.3 1.8 9.1 0.8 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX76001.1 - 0.94 10.0 4.8 0.79 10.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX76002.1 - 1.3e-07 32.1 0.3 2.6e-07 31.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain C2 PF00168.30 EAX76004.1 - 2.8e-39 133.6 0.2 3.4e-22 78.7 0.1 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 EAX76004.1 - 0.044 13.6 0.0 0.093 12.5 0.0 1.4 1 1 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins FAS_meander PF17951.1 EAX76004.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain CEP76-C2 PF15627.6 EAX76004.1 - 0.061 12.9 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 CEP76 C2 domain B9-C2 PF07162.11 EAX76004.1 - 0.078 13.2 0.0 0.52 10.5 0.0 2.1 2 1 0 2 2 2 0 Ciliary basal body-associated, B9 protein C2 PF00168.30 EAX76005.1 - 4.7e-21 75.0 0.0 6.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain DNA_pol_B_2 PF03175.13 EAX76006.1 - 3.9e-09 35.9 1.9 5.7e-09 35.4 0.9 1.7 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX76006.1 - 0.1 12.6 0.0 0.82 9.7 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAX76007.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX76009.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DNA_pol_B_2 PF03175.13 EAX76010.1 - 1.4e-10 40.7 0.3 1.4e-10 40.7 0.3 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX76011.1 - 2.6e-86 289.0 8.1 3e-86 288.8 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76011.1 - 0.026 14.1 0.4 0.028 13.9 0.4 1.1 1 0 0 1 1 1 0 Z1 domain PapD_N PF00345.20 EAX76013.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain ResIII PF04851.15 EAX76016.1 - 6.4e-05 23.0 2.4 0.00012 22.2 2.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76016.1 - 0.00032 20.5 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX76016.1 - 0.0004 20.7 0.0 0.00061 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX76016.1 - 0.00082 19.2 1.2 0.0028 17.5 1.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76016.1 - 0.0084 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76016.1 - 0.035 13.6 0.1 0.052 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX76016.1 - 0.047 13.4 0.2 0.066 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX76016.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF257 PF03192.13 EAX76018.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX76018.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PSP PF04046.16 EAX76019.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX76021.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX76021.1 - 0.051 13.6 0.6 0.073 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) FucT_N PF18025.1 EAX76021.1 - 0.18 12.3 2.8 0.39 11.2 0.3 2.5 2 1 1 3 3 3 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain Pox_D5 PF03288.16 EAX76022.1 - 4.6e-05 23.8 2.6 0.00026 21.4 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX76022.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX76023.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76024.1 - 0.15 12.0 3.0 0.19 11.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PcfK PF14058.6 EAX76025.1 - 0.22 11.8 11.8 0.32 11.3 11.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX76026.1 - 1.6e-59 200.0 8.9 1.8e-59 199.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX76027.1 - 9.8e-74 246.9 4.2 1.2e-73 246.7 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76027.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase KilA-N PF04383.13 EAX76028.1 - 1.8e-31 108.2 0.1 3.5e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF5568 PF17724.1 EAX76028.1 - 0.15 11.9 0.1 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5568) DUF5365 PF17326.2 EAX76030.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX76030.1 - 0.028 14.7 0.3 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain Flp_N PF03930.14 EAX76031.1 - 0.041 13.8 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Pox_A32 PF04665.12 EAX76033.1 - 6.5e-08 32.3 1.1 7.7e-08 32.1 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76033.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76033.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76033.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) ComA PF02679.15 EAX76034.1 - 0.056 12.9 0.7 0.067 12.6 0.7 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX76034.1 - 0.11 11.9 0.5 0.21 11.0 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX76035.1 - 3.7e-150 498.1 11.8 4.6e-150 497.8 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76035.1 - 0.1 13.0 2.0 0.18 12.2 0.3 2.0 2 0 0 2 2 2 0 Fez1 Pox_A32 PF04665.12 EAX76036.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76036.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76036.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76036.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76036.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76036.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX76036.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Hormone_3 PF00159.18 EAX76037.1 - 0.14 12.3 5.0 36 4.6 0.1 3.4 3 0 0 3 3 3 0 Pancreatic hormone peptide KilA-N PF04383.13 EAX76038.1 - 3.3e-08 33.4 0.1 7.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX76038.1 - 0.15 11.5 0.2 0.3 10.5 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX76038.1 - 1.2 9.5 4.7 4.2 7.7 0.4 2.3 1 1 0 2 2 2 0 PRD domain EssA PF10661.9 EAX76038.1 - 3.5 7.5 7.8 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX76039.1 - 6.9e-154 510.3 14.8 8e-154 510.1 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76039.1 - 0.16 11.8 1.7 0.5 10.2 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76039.1 - 0.68 10.4 5.9 3.9 8.0 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX76039.1 - 0.99 9.7 3.5 0.64 10.4 1.1 2.0 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Spectrin_like PF18373.1 EAX76040.1 - 0.0067 16.5 1.9 0.011 15.8 1.7 1.5 1 1 0 1 1 1 1 Spectrin like domain Popeye PF04831.13 EAX76040.1 - 0.066 13.4 0.1 0.074 13.2 0.1 1.2 1 0 0 1 1 1 0 Popeye protein conserved region DUF2939 PF11159.8 EAX76041.1 - 0.012 16.0 0.5 0.015 15.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76041.1 - 1.8 8.5 5.6 2 8.5 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76042.1 - 0.0091 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX76042.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal CH PF00307.31 EAX76043.1 - 0.11 12.7 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain HNH_3 PF13392.6 EAX76045.1 - 9.1e-07 28.5 0.1 2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3482 PF11981.8 EAX76045.1 - 0.18 11.2 2.6 0.073 12.5 0.4 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) E1_dh PF00676.20 EAX76045.1 - 0.19 10.7 2.7 0.35 9.8 0.5 2.0 2 0 0 2 2 2 0 Dehydrogenase E1 component PTR PF12789.7 EAX76046.1 - 2.3e-05 24.3 0.6 2.3e-05 24.3 0.6 3.9 3 2 1 4 4 4 1 Phage tail repeat like EDR1 PF14381.6 EAX76046.1 - 0.03 14.0 0.1 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4116 PF13475.6 EAX76046.1 - 0.033 13.9 0.1 0.14 11.9 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX76046.1 - 0.084 12.7 8.1 0.14 11.9 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX76046.1 - 0.52 10.8 0.0 0.52 10.8 0.0 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX76047.1 - 4e-45 153.3 1.4 4.4e-45 153.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX76049.1 - 2.8e-11 43.7 0.0 4.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Glyco_H_20C_C PF18088.1 EAX76049.1 - 0.01 15.7 0.0 0.049 13.5 0.0 1.9 1 1 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain PWI PF01480.17 EAX76049.1 - 0.098 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 PWI domain DUF3839 PF12943.7 EAX76050.1 - 1.2e-78 264.0 4.5 1.5e-78 263.6 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX76050.1 - 0.0051 16.5 0.6 0.0091 15.7 0.6 1.6 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX76050.1 - 0.094 13.0 1.9 0.18 12.1 1.9 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF1493 PF07377.12 EAX76052.1 - 0.059 13.8 0.8 0.12 12.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX76053.1 - 0.001 19.6 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX76053.1 - 0.022 14.3 0.5 0.045 13.3 0.1 1.6 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX76053.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX76054.1 - 1.5e-38 132.7 4.6 1.9e-38 132.3 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX76054.1 - 0.36 11.2 1.8 1.5 9.2 1.0 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain KilA-N PF04383.13 EAX76055.1 - 1.5e-34 118.2 0.4 3e-34 117.2 0.4 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX76055.1 - 0.014 16.0 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Parathyroid hormone family FPN1 PF06963.12 EAX76055.1 - 0.23 10.0 0.1 0.3 9.6 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RRP36 PF06102.12 EAX76055.1 - 0.37 10.7 7.4 0.15 12.0 2.7 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 LOH1CR12 PF10158.9 EAX76055.1 - 0.61 10.1 4.8 1.4 8.9 0.5 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX76056.1 - 5.4e-07 29.3 2.8 5.4e-07 29.3 2.8 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76056.1 - 1.9e-05 24.9 0.2 0.00014 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX76056.1 - 0.00016 21.8 3.2 0.00037 20.5 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX76056.1 - 0.00025 20.8 0.3 0.43 10.3 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX76056.1 - 0.00067 19.5 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX76056.1 - 0.0012 18.6 0.4 0.0075 15.9 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX76056.1 - 0.0015 18.4 0.7 0.0045 16.8 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76056.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX76056.1 - 0.059 12.9 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX76056.1 - 0.071 13.5 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76056.1 - 0.081 12.4 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX76056.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Gly-zipper_Omp PF13488.6 EAX76059.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX76059.1 - 0.24 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76059.1 - 0.85 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX76060.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76061.1 - 0.067 13.1 0.8 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX76062.1 - 0.0035 17.4 0.2 0.0047 16.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX76063.1 - 0.021 15.2 0.4 0.031 14.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76063.1 - 2 8.4 4.9 2.1 8.4 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX76065.1 - 4.4e-45 152.1 0.1 4.4e-45 152.1 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX76065.1 - 0.022 15.0 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DNA_pol_B_2 PF03175.13 EAX76066.1 - 1e-21 77.4 4.2 1.5e-21 76.9 4.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX76066.1 - 0.093 13.0 0.0 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) Pox_A32 PF04665.12 EAX76067.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX76068.1 - 6.4e-67 224.7 5.3 9.8e-67 224.1 5.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX76069.1 - 0.0085 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pec_lyase_N PF04431.13 EAX76072.1 - 0.0094 16.2 0.2 0.028 14.7 0.2 1.8 1 0 0 1 1 1 1 Pectate lyase, N terminus PTR PF12789.7 EAX76073.1 - 5.5e-10 39.2 6.1 5.5e-10 39.2 6.1 3.1 4 0 0 4 4 4 1 Phage tail repeat like BRO1 PF03097.18 EAX76073.1 - 0.036 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF3839 PF12943.7 EAX76074.1 - 6.8e-117 389.2 5.7 7.9e-117 388.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RRM_Rrp7 PF17799.1 EAX76074.1 - 0.067 13.0 0.6 0.09 12.6 0.6 1.4 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Glu-tRNAGln PF02686.15 EAX76074.1 - 0.22 11.8 1.2 0.56 10.5 1.2 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX76074.1 - 1.8 8.9 4.8 4.3 7.7 0.1 2.9 2 1 1 3 3 3 0 Rx N-terminal domain KilA-N PF04383.13 EAX76075.1 - 4e-14 52.4 0.2 7.2e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76075.1 - 0.03 14.3 1.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX76075.1 - 0.11 11.9 0.3 0.27 10.6 0.3 1.7 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain JMY PF15871.5 EAX76077.1 - 0.035 13.4 0.3 0.051 12.9 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX76077.1 - 0.16 12.0 2.6 0.73 9.9 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4107 PF13389.6 EAX76079.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX76082.1 - 0.022 14.6 1.1 0.051 13.4 1.1 1.7 1 1 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX76082.1 - 0.033 13.4 0.1 0.034 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX76082.1 - 0.054 13.0 0.2 0.076 12.5 0.2 1.2 1 0 0 1 1 1 0 Legume lectin domain DUF3839 PF12943.7 EAX76083.1 - 5.7e-25 88.2 4.9 8.7e-25 87.6 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX76085.1 - 2.1e-21 76.3 5.8 3.4e-10 40.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX76085.1 - 4.1e-16 57.4 4.5 0.0086 16.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX76085.1 - 4.2e-11 43.2 3.8 0.00048 20.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX76085.1 - 5.1e-08 33.0 2.9 0.093 13.1 0.0 4.9 1 1 5 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX76085.1 - 5.3e-05 23.5 4.5 1.1 9.8 0.0 5.4 6 1 1 7 7 7 2 Ankyrin repeat ASD1 PF08688.10 EAX76086.1 - 0.086 13.2 2.0 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD1 CTU2 PF10288.9 EAX76086.1 - 0.83 9.9 4.5 4.6 7.5 0.1 2.6 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 KilA-N PF04383.13 EAX76088.1 - 1.3e-14 53.9 0.0 2.8e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain DUF2939 PF11159.8 EAX76089.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76089.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX76089.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF1043 PF06295.12 EAX76090.1 - 0.14 12.2 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX76091.1 - 6.6e-91 304.1 8.9 7.5e-91 303.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX76091.1 - 0.18 12.3 1.5 0.56 10.7 1.5 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GGDEF PF00990.21 EAX76092.1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX76092.1 - 1.3 9.0 5.3 2.6 8.0 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) EpuA PF11772.8 EAX76093.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Phage_fiber PF03335.13 EAX76093.1 - 2.4 8.5 20.4 1.5 9.2 3.0 3.5 2 1 1 3 3 3 0 Phage tail fibre repeat Gly_rich PF12810.7 EAX76094.1 - 7.2e-55 186.5 41.3 9.7e-55 186.1 41.3 1.2 1 0 0 1 1 1 1 Glycine rich protein DDE_Tnp_4 PF13359.6 EAX76096.1 - 1.5e-32 112.5 0.0 1.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX76096.1 - 5.4e-09 36.0 0.1 3.3e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain DUF4108 PF13390.6 EAX76098.1 - 1.1e-55 187.4 7.6 1.3e-55 187.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76098.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX76099.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF5348 PF17295.2 EAX76100.1 - 0.07 13.1 0.1 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5348) Phage_fiber PF03335.13 EAX76100.1 - 0.25 11.6 6.4 1.6 9.1 1.3 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF4107 PF13389.6 EAX76103.1 - 1.2e-71 240.1 3.8 1.5e-71 239.8 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76103.1 - 0.17 10.3 0.7 0.22 9.9 0.7 1.2 1 0 0 1 1 1 0 Lipoxygenase T5orf172 PF10544.9 EAX76104.1 - 1.2e-06 29.0 0.2 2.5e-06 28.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76105.1 - 6.2e-42 142.0 1.0 1e-41 141.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76105.1 - 0.0052 17.4 0.1 0.02 15.5 0.0 2.0 2 0 0 2 2 2 1 Parathyroid hormone family Laminin_I PF06008.14 EAX76106.1 - 4e-08 33.3 25.2 0.00039 20.2 4.2 3.3 1 1 2 3 3 3 3 Laminin Domain I Sec34 PF04136.15 EAX76106.1 - 0.0022 17.9 37.9 0.56 10.1 3.1 4.8 1 1 4 5 5 5 4 Sec34-like family GCN5L1 PF06320.13 EAX76106.1 - 0.0046 17.1 13.5 3 8.0 2.4 4.1 1 1 3 4 4 4 1 GCN5-like protein 1 (GCN5L1) KASH_CCD PF14662.6 EAX76106.1 - 0.0048 16.8 25.5 0.049 13.4 6.4 2.9 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX76106.1 - 0.0079 15.6 11.3 4.9 6.5 3.5 3.7 1 1 3 4 4 4 1 Domain of unknown function (DUF3552) RNase_E_G PF10150.9 EAX76106.1 - 0.019 14.4 5.6 0.15 11.5 4.0 2.6 1 1 1 2 2 2 0 Ribonuclease E/G family UPF0449 PF15136.6 EAX76106.1 - 0.03 14.8 21.4 1.9 9.0 1.8 4.5 1 1 4 5 5 5 0 Uncharacterised protein family UPF0449 YabA PF06156.13 EAX76106.1 - 0.039 14.6 7.9 22 5.8 2.9 3.9 1 1 0 2 2 2 0 Initiation control protein YabA ERM PF00769.19 EAX76106.1 - 0.046 13.5 13.9 0.18 11.6 11.9 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EAX76106.1 - 0.16 11.3 38.2 0.067 12.5 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 EAX76106.1 - 0.17 10.8 22.0 1.1 8.1 2.3 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein ZapB PF06005.12 EAX76106.1 - 0.35 11.3 13.8 16 6.0 1.6 4.4 1 1 2 3 3 3 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EAX76106.1 - 0.37 10.7 5.2 11 5.9 0.4 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain JIP_LZII PF16471.5 EAX76106.1 - 0.38 10.9 9.6 41 4.4 0.0 5.2 1 1 4 6 6 6 0 JNK-interacting protein leucine zipper II Prominin PF05478.11 EAX76106.1 - 0.68 7.8 22.1 0.67 7.8 8.3 2.8 1 1 1 2 2 2 0 Prominin DUF948 PF06103.11 EAX76106.1 - 0.73 10.1 8.8 15 5.9 0.2 3.8 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YojJ PF10372.9 EAX76106.1 - 0.85 9.8 20.8 2.7 8.1 1.8 5.4 1 1 5 6 6 6 0 Bacterial membrane-spanning protein N-terminus Exonuc_VII_L PF02601.15 EAX76106.1 - 0.93 9.0 32.5 1.4 8.4 12.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 EAX76106.1 - 0.97 9.6 25.8 1 9.6 4.0 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Apolipoprotein PF01442.18 EAX76106.1 - 0.98 9.3 28.5 0.035 14.0 10.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 EAX76106.1 - 1.5 8.9 38.3 2.9 8.0 12.4 3.4 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 EAX76106.1 - 1.6 8.4 10.3 15 5.3 1.7 3.0 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 EAX76106.1 - 1.7 8.6 24.4 7.5 6.6 1.0 3.6 1 1 3 4 4 4 0 Laminin Domain II BRE1 PF08647.11 EAX76106.1 - 2.6 8.2 18.5 7.3 6.7 5.0 3.6 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EAX76106.1 - 3.7 8.1 24.8 6.8 7.2 6.9 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region TMCO5 PF14992.6 EAX76106.1 - 9.1 5.8 7.2 10 5.6 3.7 2.2 1 1 1 2 2 2 0 TMCO5 family Serine_rich PF08824.10 EAX76106.1 - 9.2 6.3 30.3 5.9 6.9 15.1 3.1 1 1 2 3 3 3 0 Serine rich protein interaction domain DUF4795 PF16043.5 EAX76106.1 - 9.2 5.8 22.6 8.7 5.9 4.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Pox_D5 PF03288.16 EAX76108.1 - 0.00013 22.3 3.5 0.001 19.5 3.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX76109.1 - 1.3e-57 193.7 6.1 1.4e-57 193.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX76110.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2939 PF11159.8 EAX76111.1 - 0.016 15.6 0.4 0.019 15.4 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76111.1 - 5.2 7.1 6.2 5.4 7.0 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76112.1 - 0.0062 16.5 0.1 0.0085 16.1 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta T5orf172 PF10544.9 EAX76113.1 - 8.8e-05 23.0 0.6 0.00025 21.6 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX76113.1 - 0.027 14.3 0.1 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX76114.1 - 9.9e-40 134.9 1.0 1.6e-39 134.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76114.1 - 0.033 14.8 0.0 0.084 13.5 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family KilA-N PF04383.13 EAX76115.1 - 7.6e-36 122.4 0.3 2.3e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76115.1 - 0.02 15.5 0.1 0.047 14.3 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF3653 PF12375.8 EAX76116.1 - 0.0029 17.7 0.4 5.2 7.3 0.0 3.1 3 0 0 3 3 3 2 Phage protein RRM_1 PF00076.22 EAX76117.1 - 4.6e-16 58.4 0.2 2.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX76117.1 - 9.9e-08 31.6 0.0 5e-07 29.4 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX76117.1 - 1.8e-05 24.5 0.0 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RrnaAD PF00398.20 EAX76117.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase YL1 PF05764.13 EAX76118.1 - 0.051 13.7 9.3 0.067 13.3 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PK_C PF02887.16 EAX76118.1 - 0.053 13.8 0.4 0.084 13.1 0.4 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain WW_FCH_linker PF16623.5 EAX76118.1 - 0.29 11.9 7.5 2 9.2 3.2 2.7 1 1 1 2 2 2 0 Unstructured linker region between on GAS7 protein DUF2689 PF10894.8 EAX76119.1 - 0.087 12.6 0.6 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) SHIPPO-rpt PF07004.12 EAX76119.1 - 5.9 8.0 9.0 3.3e+02 2.5 5.4 3.8 2 1 0 2 2 2 0 Sperm-tail PG-rich repeat DUF3839 PF12943.7 EAX76120.1 - 3.6e-136 452.3 11.6 4e-136 452.1 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trns_repr_metal PF02583.17 EAX76120.1 - 0.14 12.5 0.2 8.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor GPS2_interact PF15784.5 EAX76121.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76121.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX76122.1 - 0.027 14.5 8.1 0.041 13.9 8.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX76125.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX76126.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX76127.1 - 4.5e-33 113.5 0.2 1.2e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76127.1 - 0.052 14.2 0.1 0.13 12.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX76128.1 - 3.4e-98 327.9 7.5 3.8e-98 327.8 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX76129.1 - 9.8e-123 408.3 9.8 3.3e-122 406.6 9.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX76131.1 - 6.2e-39 133.9 4.9 9e-39 133.4 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX76131.1 - 0.03 13.5 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX76131.1 - 0.087 13.3 0.2 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB THOC7 PF05615.13 EAX76131.1 - 0.11 12.8 1.1 0.29 11.4 1.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Collagen_bind_2 PF12904.7 EAX76132.1 - 0.11 12.4 0.1 4.2 7.4 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase YmaF PF12788.7 EAX76133.1 - 0.19 12.3 1.5 11 6.6 0.1 2.1 1 1 0 2 2 2 0 YmaF family GPS2_interact PF15784.5 EAX76135.1 - 0.099 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Borrelia_P83 PF05262.11 EAX76137.1 - 0.00083 18.0 24.2 0.0017 17.0 24.2 1.5 1 0 0 1 1 1 1 Borrelia P83/100 protein CDC45 PF02724.14 EAX76137.1 - 0.03 12.6 17.0 0.042 12.2 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF445 PF04286.12 EAX76137.1 - 1.6 8.5 16.0 0.64 9.8 12.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) V_ATPase_I PF01496.19 EAX76137.1 - 3.8 5.3 9.8 6.9 4.4 9.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4551 PF15087.6 EAX76137.1 - 5 5.8 22.3 8.3 5.1 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mito_fiss_reg PF05308.11 EAX76138.1 - 0.13 12.4 0.7 0.13 12.3 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX76138.1 - 0.76 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Toxin_R_bind_C PF07951.12 EAX76139.1 - 0.062 12.9 2.1 0.047 13.3 0.8 1.5 2 0 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding YfbU PF03887.14 EAX76139.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 YfbU domain Antimicrobial_8 PF08103.11 EAX76139.1 - 9 6.7 6.3 1.5 9.1 0.6 2.6 2 0 0 2 2 2 0 Uperin family DUF3839 PF12943.7 EAX76140.1 - 2.2e-121 403.9 5.4 2.4e-121 403.7 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX76140.1 - 0.22 12.0 2.0 1 9.8 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX76141.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76141.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PapD_N PF00345.20 EAX76142.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX76143.1 - 0.035 14.5 0.4 0.043 14.2 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Efg1 PF10153.9 EAX76143.1 - 0.78 10.1 11.0 0.86 10.0 11.0 1.1 1 0 0 1 1 1 0 rRNA-processing protein Efg1 TERB2 PF15101.6 EAX76143.1 - 0.79 9.7 5.5 0.85 9.6 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX76143.1 - 1.4 7.9 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein FAS_N PF17828.1 EAX76144.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX76145.1 - 3.8e-91 304.8 8.6 4.4e-91 304.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX76146.1 - 6.7e-07 29.8 0.5 2.2e-06 28.1 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX76146.1 - 0.11 12.3 1.1 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX76146.1 - 0.16 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX76147.1 - 6.8e-31 106.4 0.1 1.1e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX76149.1 - 2.5e-07 30.4 2.5 2.5e-07 30.4 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76149.1 - 1.1e-05 25.8 0.2 6.8e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76149.1 - 1.9e-05 24.5 0.3 0.23 11.2 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX76149.1 - 9.3e-05 22.5 4.3 0.00017 21.6 3.6 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76149.1 - 0.0002 21.2 0.1 0.00038 20.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76149.1 - 0.0009 19.1 1.0 0.0018 18.1 1.0 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76149.1 - 0.0013 18.4 0.5 0.0095 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76149.1 - 0.008 16.5 0.0 0.021 15.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EAX76149.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX76149.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX76149.1 - 0.092 13.2 0.1 0.78 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAX76149.1 - 0.17 11.6 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX76149.1 - 0.46 10.8 4.6 8.3 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX76151.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76151.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76151.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76151.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) YvrJ PF12841.7 EAX76152.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family FliD_N PF02465.18 EAX76153.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX76153.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF5077 PF16871.5 EAX76155.1 - 0.18 11.7 2.7 0.26 11.2 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) MGC-24 PF05283.11 EAX76155.1 - 0.45 11.0 5.0 0.74 10.3 5.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4106 PF13388.6 EAX76156.1 - 3e-96 323.2 5.5 6.1e-96 322.2 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4378 PF14309.6 EAX76156.1 - 0.041 14.3 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) DUF3839 PF12943.7 EAX76157.1 - 1.5e-79 266.9 9.0 1.9e-79 266.5 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX76157.1 - 0.092 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Pox_A32 PF04665.12 EAX76158.1 - 2.6e-07 30.3 3.0 4.1e-07 29.7 3.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76158.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76158.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76158.1 - 0.062 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76158.1 - 0.082 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76158.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX76158.1 - 0.39 10.9 8.5 5.7 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Protoglobin PF11563.8 EAX76160.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protoglobin DNA_pol_B_2 PF03175.13 EAX76161.1 - 1.6e-29 103.1 7.7 2.7e-29 102.4 7.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76161.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Gly-zipper_Omp PF13488.6 EAX76163.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX76163.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF3839 PF12943.7 EAX76164.1 - 1.6e-156 518.9 11.9 2e-156 518.6 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76164.1 - 0.099 12.5 0.9 0.29 11.0 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX76164.1 - 0.44 10.9 4.5 1.5 9.1 0.1 3.3 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX76164.1 - 1.6 9.3 6.8 1.9 9.0 0.6 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ly49 PF08391.10 EAX76165.1 - 1.2 9.5 4.8 0.66 10.3 3.0 1.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Gly-zipper_Omp PF13488.6 EAX76166.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX76166.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX76166.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX76166.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76166.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Apolipoprotein PF01442.18 EAX76167.1 - 0.2 11.5 0.0 0.22 11.4 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain KilA-N PF04383.13 EAX76168.1 - 4.1e-40 136.1 0.5 4.1e-40 136.1 0.5 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76168.1 - 0.016 15.9 0.0 0.047 14.3 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family DUF2939 PF11159.8 EAX76169.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76169.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76169.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX76169.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76170.1 - 0.0075 16.3 0.2 0.01 15.8 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX76171.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX76172.1 - 5.9e-47 159.8 4.8 9.8e-47 159.1 4.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76172.1 - 0.062 13.7 0.1 0.074 13.4 0.1 1.1 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta SGP PF17228.2 EAX76172.1 - 0.16 12.8 2.0 0.3 11.9 2.0 1.5 1 1 0 1 1 1 0 Sulphur globule protein KilA-N PF04383.13 EAX76173.1 - 4.8e-41 139.1 0.1 7e-41 138.6 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX76174.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Amidase02_C PF12123.8 EAX76175.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX76175.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX76176.1 - 4e-23 81.4 0.3 5.9e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76176.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4108 PF13390.6 EAX76177.1 - 2.4e-63 212.3 6.9 2.7e-63 212.2 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76177.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4107 PF13389.6 EAX76179.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX76180.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX76181.1 - 0.00022 20.8 2.6 0.00032 20.2 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76181.1 - 0.0031 17.2 0.2 0.0041 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76181.1 - 0.025 14.1 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76181.1 - 0.035 13.9 0.2 0.19 11.4 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76181.1 - 0.048 13.4 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76181.1 - 0.17 11.9 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX76181.1 - 0.2 12.1 2.3 0.29 11.6 1.0 1.9 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 GPS2_interact PF15784.5 EAX76184.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76184.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX76187.1 - 2.5e-57 192.8 5.0 2.8e-57 192.7 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX76189.1 - 0.061 13.8 0.6 0.12 12.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Trypan_PARP PF05887.11 EAX76190.1 - 0.023 14.7 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX76190.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76191.1 - 0.064 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX76192.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76192.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX76195.1 - 2.2e-156 518.5 12.9 2.5e-156 518.3 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76195.1 - 0.11 12.3 0.9 0.37 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76195.1 - 1.1 9.7 4.6 4.4 7.8 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX76196.1 - 8.4e-08 32.7 0.5 1.7e-07 31.7 0.5 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX76196.1 - 0.15 12.7 0.5 0.43 11.3 0.5 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX76197.1 - 2.5e-11 43.4 0.5 6.5e-11 42.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX76199.1 - 4.4e-51 170.8 44.4 7.7e-30 102.7 19.5 6.2 4 2 1 5 5 5 4 Phage tail repeat like PH_TFIIH PF08567.11 EAX76199.1 - 0.83 10.0 4.6 47 4.4 0.1 3.6 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain EssA PF10661.9 EAX76200.1 - 5.1 6.9 8.3 13 5.6 8.3 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX76203.1 - 1.3e-16 60.8 3.4 2e-16 60.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX76204.1 - 1.1e-05 25.9 0.2 3e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76204.1 - 0.024 14.5 0.2 0.077 12.9 0.1 2.0 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX76204.1 - 0.15 11.6 0.2 1.2 8.6 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF257 PF03192.13 EAX76205.1 - 0.00097 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX76205.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3839 PF12943.7 EAX76206.1 - 4.9e-128 425.6 8.1 5.6e-128 425.5 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX76206.1 - 0.083 12.4 0.1 0.26 10.8 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 Rx_N PF18052.1 EAX76206.1 - 0.29 11.4 1.9 2.2 8.6 0.0 2.8 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76206.1 - 0.36 11.3 2.1 1.3 9.6 1.0 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX76207.1 - 0.068 13.1 0.8 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76208.1 - 0.047 14.2 4.8 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX76209.1 - 0.063 13.7 1.0 0.11 13.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX76210.1 - 1.1e-06 28.3 1.3 1.3e-06 28.1 1.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX76210.1 - 0.034 14.1 0.4 0.37 10.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX76211.1 - 9.2e-16 57.7 0.6 2.5e-15 56.3 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX76211.1 - 0.0026 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF2400 PF09674.10 EAX76213.1 - 0.013 15.5 0.3 0.017 15.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX76213.1 - 0.054 13.5 0.3 0.066 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX76213.1 - 0.075 12.9 0.1 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX76214.1 - 0.015 15.7 0.5 0.021 15.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX76214.1 - 2.9 8.5 6.4 6.9 7.4 6.4 1.7 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX76215.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX76216.1 - 1.3e-06 28.0 3.6 1.6e-06 27.8 2.2 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76216.1 - 2.8e-05 24.4 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76216.1 - 3.3e-05 23.7 0.3 0.42 10.3 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX76216.1 - 0.00016 21.7 3.5 0.00035 20.6 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76216.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76216.1 - 0.0015 18.4 0.8 0.0039 17.0 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76216.1 - 0.0019 17.9 0.5 0.012 15.3 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76216.1 - 0.011 16.0 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX76216.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX76216.1 - 0.076 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX76216.1 - 0.079 13.4 0.1 0.66 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76216.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX76216.1 - 0.7 10.2 4.3 16 5.9 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX76218.1 - 7.3e-114 379.2 9.4 8.2e-114 379.1 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX76219.1 - 1.5e-07 31.1 1.4 1.2e-06 28.1 0.0 2.5 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX76219.1 - 0.019 14.6 0.1 0.39 10.3 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76219.1 - 0.077 12.9 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Thymidine kinase PBAN PF05874.11 EAX76219.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) AAA_33 PF13671.6 EAX76219.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1947 PF09183.10 EAX76221.1 - 0.054 13.8 0.6 0.26 11.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) DUF3839 PF12943.7 EAX76222.1 - 1.2e-156 519.4 13.0 1.5e-156 519.0 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76222.1 - 0.11 12.3 0.7 0.35 10.7 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX76222.1 - 1.1 9.7 3.5 0.96 9.8 1.1 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX76222.1 - 1.2 9.7 4.9 1.2 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX76223.1 - 1.2e-17 64.0 1.6 1.4e-17 63.7 1.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX76225.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX76227.1 - 2.7e-07 30.3 2.8 4e-07 29.7 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76227.1 - 0.0047 16.6 0.1 0.0062 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76227.1 - 0.07 12.9 0.1 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76227.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76227.1 - 0.2 11.6 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF4795 PF16043.5 EAX76229.1 - 0.023 14.3 13.5 2 8.0 4.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX76229.1 - 0.031 14.3 0.3 0.031 14.3 0.3 3.1 3 0 0 3 3 3 0 Phage tail repeat like DUF2018 PF09442.10 EAX76229.1 - 0.11 13.5 1.0 0.42 11.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) FAS_N PF17828.1 EAX76230.1 - 0.013 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX76231.1 - 0.01 16.2 1.1 0.012 16.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX76231.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX76231.1 - 10 6.1 9.5 11 6.0 9.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX76232.1 - 0.06 13.4 0.1 0.069 13.2 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX76232.1 - 0.083 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX76232.1 - 0.45 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX76233.1 - 2e-55 186.7 6.5 2.2e-55 186.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76233.1 - 0.1 12.9 0.1 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX76234.1 - 0.045 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3839 PF12943.7 EAX76237.1 - 1.9e-144 479.4 9.2 2.4e-144 479.1 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX76237.1 - 0.8 10.0 4.8 10 6.5 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX76238.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX76238.1 - 0.15 11.5 0.2 0.3 10.5 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX76238.1 - 1.5 9.1 4.9 4.4 7.7 0.4 2.3 1 1 0 2 2 2 0 PRD domain EssA PF10661.9 EAX76238.1 - 3.6 7.4 7.8 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA ASD1 PF08688.10 EAX76239.1 - 0.0031 17.9 0.1 0.0037 17.7 0.1 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD1 PapD_N PF00345.20 EAX76241.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TMP PF05017.14 EAX76242.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX76243.1 - 0.012 16.1 0.9 0.022 15.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX76244.1 - 9.7e-07 29.3 0.3 1.9e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX76245.1 - 2.3e-29 102.6 7.9 4.2e-29 101.8 7.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76245.1 - 0.0098 15.2 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5106 PF17127.4 EAX76245.1 - 0.065 13.5 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF5065 PF16723.5 EAX76245.1 - 0.13 12.3 0.6 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4378 PF14309.6 EAX76246.1 - 0.021 15.2 0.1 0.079 13.3 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) T5orf172 PF10544.9 EAX76247.1 - 8.4e-07 29.5 0.2 1.6e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76248.1 - 4.8e-34 116.6 0.7 8.8e-34 115.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX76249.1 - 3.4e-44 149.3 1.1 5.3e-44 148.7 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76249.1 - 0.019 15.6 0.1 0.067 13.8 0.0 2.0 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX76250.1 - 1.7e-06 28.5 0.2 3.3e-06 27.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX76250.1 - 0.16 12.7 0.3 0.43 11.3 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3839 PF12943.7 EAX76251.1 - 7.9e-72 241.6 5.5 1e-71 241.2 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX76251.1 - 0.03 14.3 0.4 7.5 6.6 0.0 2.2 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region T5orf172 PF10544.9 EAX76252.1 - 4.8e-05 23.8 0.5 0.00086 19.8 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX76252.1 - 0.0075 15.5 0.1 0.014 14.6 0.0 1.5 1 1 1 2 2 2 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX76252.1 - 0.032 13.8 0.6 0.24 10.9 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain Fe-ADH PF00465.19 EAX76254.1 - 7.2e-09 34.9 0.0 7.8e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF761 PF05553.11 EAX76254.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Cotton fibre expressed protein Cytadhesin_P30 PF07271.11 EAX76256.1 - 5.1 6.6 18.1 6.3 6.3 18.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Trypan_PARP PF05887.11 EAX76257.1 - 0.11 12.5 7.6 0.17 11.9 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ArsC PF03960.15 EAX76261.1 - 0.097 12.7 1.0 0.14 12.2 1.0 1.5 1 1 0 1 1 1 0 ArsC family PTR PF12789.7 EAX76262.1 - 1.8e-05 24.7 0.4 1.8e-05 24.7 0.4 3.4 2 1 1 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX76262.1 - 0.0037 17.1 6.4 0.0053 16.6 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX76262.1 - 0.019 15.4 1.1 0.11 13.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF2120 PF09893.9 EAX76262.1 - 0.024 14.7 2.4 0.37 10.9 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1048 PF06304.11 EAX76262.1 - 0.032 14.7 0.6 0.11 12.9 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF4116 PF13475.6 EAX76262.1 - 0.061 13.1 0.1 0.23 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) ATP-cone PF03477.16 EAX76262.1 - 0.29 11.7 2.6 1.2 9.8 0.4 2.7 1 1 2 3 3 3 0 ATP cone domain PKcGMP_CC PF16808.5 EAX76262.1 - 3 7.8 6.6 2.3 8.1 0.3 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spo12 PF05032.12 EAX76263.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX76264.1 - 3.5e-19 68.7 0.1 4.5e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX76265.1 - 8e-22 77.7 5.7 1.1e-21 77.2 5.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX76266.1 - 2.7e-79 266.0 10.8 3.5e-79 265.7 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX76266.1 - 0.46 10.6 2.9 2.1 8.5 1.2 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PSP PF04046.16 EAX76267.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76268.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76269.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX76272.1 - 0.0058 16.3 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX76272.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX76273.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76273.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX76275.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase HTH_16 PF12645.7 EAX76276.1 - 0.084 12.9 0.0 0.63 10.1 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain Myb_DNA-binding PF00249.31 EAX76277.1 - 6.2e-14 51.9 0.5 4.1e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX76277.1 - 1.1e-11 44.8 3.5 2.7e-06 27.5 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX76277.1 - 0.0015 18.4 1.4 0.0032 17.3 1.2 1.7 1 1 0 1 1 1 1 Myb DNA-binding like DUF4108 PF13390.6 EAX76280.1 - 1.9e-59 199.7 7.8 2.1e-59 199.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX76283.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Ras PF00071.22 EAX76284.1 - 1.7e-23 83.0 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EAX76284.1 - 8e-07 28.7 0.0 9.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX76284.1 - 3.6e-05 23.9 0.0 9.4e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAX76284.1 - 0.098 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Thioredoxin_14 PF18402.1 EAX76284.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain YvrJ PF12841.7 EAX76285.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family FliD_N PF02465.18 EAX76286.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX76286.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DDE_Tnp_4 PF13359.6 EAX76287.1 - 2.3e-31 108.6 0.0 5e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX76287.1 - 1.7e-09 37.6 0.1 2.8e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAX76287.1 - 3.9e-08 33.2 0.1 1.7e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain UCH_1 PF13423.6 EAX76287.1 - 0.00044 19.9 0.1 0.001 18.7 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Fungal_lectin_2 PF18647.1 EAX76287.1 - 0.088 13.3 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin DUF2897 PF11446.8 EAX76288.1 - 0.34 10.8 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76289.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Meiosis_expr PF15163.6 EAX76291.1 - 0.03 15.0 1.3 0.038 14.7 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX76291.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family PTR PF12789.7 EAX76294.1 - 8.5e-11 41.7 4.0 1.2e-08 34.8 0.4 5.1 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX76294.1 - 0.073 12.8 0.1 0.29 10.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Phage_fiber PF03335.13 EAX76294.1 - 9.5 6.7 14.9 5 7.6 1.1 3.6 3 0 0 3 3 3 0 Phage tail fibre repeat T5orf172 PF10544.9 EAX76295.1 - 0.0002 21.9 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76295.1 - 0.0061 16.4 0.8 0.024 14.5 0.5 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX76295.1 - 0.095 12.2 0.5 0.31 10.5 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain MULE PF10551.9 EAX76296.1 - 1.6e-13 50.9 2.4 2.1e-13 50.5 0.6 2.2 2 0 0 2 2 2 1 MULE transposase domain WRKY PF03106.15 EAX76296.1 - 0.033 14.4 2.5 0.069 13.4 0.7 2.4 1 1 1 2 2 2 0 WRKY DNA -binding domain Transposase_mut PF00872.18 EAX76296.1 - 0.44 9.4 4.5 0.082 11.8 0.3 1.8 2 0 0 2 2 2 0 Transposase, Mutator family DUF4106 PF13388.6 EAX76297.1 - 3.2e-272 902.9 18.0 4e-272 902.6 18.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76297.1 - 0.017 15.4 0.1 0.57 10.5 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated PT PF04886.12 EAX76297.1 - 0.61 9.7 45.1 0.053 13.1 31.7 2.6 1 1 1 2 2 2 0 PT repeat WBS_methylT PF12589.8 EAX76297.1 - 4.7 8.0 7.2 26 5.7 1.3 2.9 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Caskin-tail PF16632.5 EAX76298.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin DUF4887 PF16228.5 EAX76299.1 - 0.18 12.0 2.7 0.23 11.6 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DUF1493 PF07377.12 EAX76300.1 - 0.057 13.9 1.2 0.078 13.4 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX76301.1 - 7.6e-110 359.0 73.8 4e-33 113.3 14.9 5.1 2 2 3 5 5 5 4 Phage tail repeat like DUF4116 PF13475.6 EAX76301.1 - 0.13 12.0 0.9 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) IstB_IS21 PF01695.17 EAX76303.1 - 2.4e-05 24.1 0.2 0.26 11.0 0.0 2.5 1 1 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX76303.1 - 4.3e-05 23.8 0.2 0.00027 21.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX76303.1 - 0.00022 21.3 3.8 0.00036 20.6 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 EAX76303.1 - 0.00048 19.7 2.0 0.00048 19.7 2.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 EAX76303.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76303.1 - 0.002 17.9 0.3 0.0046 16.8 0.2 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76303.1 - 0.0043 16.7 2.9 0.0077 15.9 0.7 2.3 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76303.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX76303.1 - 0.048 13.2 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX76303.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX76303.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX76303.1 - 0.13 12.6 0.7 0.7 10.3 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX76303.1 - 1.1 9.9 8.9 0.23 12.1 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX76303.1 - 2 8.7 5.8 9.2 6.6 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX76304.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76305.1 - 1.8 8.5 3.7 3.9 7.4 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX76306.1 - 1e-29 102.3 11.5 1e-29 102.3 11.5 3.8 5 0 0 5 5 5 1 Phage tail repeat like DUF240 PF03086.14 EAX76306.1 - 5.6 6.9 8.7 2.3 8.2 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) Pox_A32 PF04665.12 EAX76307.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76307.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76307.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76307.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX76310.1 - 2e-05 24.5 0.6 2e-05 24.5 0.6 2.6 3 0 0 3 3 3 1 Phage tail repeat like MpPF1 PF07668.11 EAX76310.1 - 0.0047 16.2 0.3 0.007 15.7 0.3 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 1 DUF445 PF04286.12 EAX76310.1 - 0.019 14.8 0.6 0.026 14.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX76310.1 - 0.024 14.4 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX76310.1 - 0.031 13.9 3.6 0.068 12.8 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX76310.1 - 0.033 14.6 0.3 0.11 12.9 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) ASL_C PF08328.11 EAX76311.1 - 0.069 13.2 2.3 0.13 12.3 2.3 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal LMBR1 PF04791.16 EAX76311.1 - 0.093 11.6 4.3 0.11 11.4 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pox_A32 PF04665.12 EAX76312.1 - 2.7e-07 30.3 2.7 3.8e-07 29.8 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76312.1 - 0.0058 16.3 0.1 0.0077 15.9 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76312.1 - 0.049 13.1 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76312.1 - 0.067 12.9 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76312.1 - 0.097 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76312.1 - 0.14 12.1 2.2 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX76312.1 - 0.15 12.5 2.3 0.22 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Tmemb_9 PF05434.11 EAX76313.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 DUF3574 PF12098.8 EAX76314.1 - 0.14 12.0 0.9 0.2 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) ATP-synt_DE PF00401.20 EAX76314.1 - 0.42 10.9 4.8 6.6 7.1 0.3 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF4108 PF13390.6 EAX76316.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TPR_MLP1_2 PF07926.12 EAX76317.1 - 0.012 15.6 0.6 0.015 15.3 0.6 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX76317.1 - 0.058 13.2 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein AAA_11 PF13086.6 EAX76319.1 - 0.0021 17.9 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX76319.1 - 0.0047 17.2 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76319.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX76319.1 - 0.019 14.5 0.1 0.025 14.0 0.1 1.2 1 1 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX76319.1 - 0.023 14.7 0.1 0.029 14.4 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EAX76319.1 - 0.04 13.5 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX76319.1 - 0.098 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4106 PF13388.6 EAX76321.1 - 1.7e-123 413.0 30.2 1.7e-123 413.0 30.2 2.3 2 2 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76321.1 - 0.018 15.3 3.6 0.38 11.1 0.2 3.5 3 1 0 3 3 3 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX76321.1 - 1 9.2 8.7 0.21 11.4 0.3 2.7 2 1 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) PSP PF04046.16 EAX76322.1 - 0.073 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX76323.1 - 2.8e-269 893.2 34.7 2.8e-267 886.6 34.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX76323.1 - 0.021 14.7 0.1 0.055 13.3 0.1 1.7 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) KAR PF15222.6 EAX76323.1 - 0.022 15.0 0.1 0.88 9.9 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated PTR PF12789.7 EAX76324.1 - 3.8e-65 215.8 44.5 6.4e-35 119.0 16.3 5.7 3 2 2 6 6 6 3 Phage tail repeat like DUF1493 PF07377.12 EAX76325.1 - 0.026 15.0 1.5 0.034 14.6 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) ARA70 PF12489.8 EAX76326.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Gly-zipper_Omp PF13488.6 EAX76327.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX76327.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76327.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX76328.1 - 2.2e-06 27.3 0.8 2.6e-06 27.1 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX76328.1 - 0.036 14.0 0.4 0.31 11.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Zot PF05707.12 EAX76328.1 - 0.064 12.9 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76328.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein VirE PF05272.11 EAX76329.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E RNA_helicase PF00910.22 EAX76329.1 - 0.08 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EAX76329.1 - 0.08 11.8 0.2 7.1 5.4 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KHA PF11834.8 EAX76332.1 - 0.00074 19.6 0.1 0.0016 18.5 0.1 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel DCX PF03607.17 EAX76332.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Doublecortin Aa_trans PF01490.18 EAX76333.1 - 1.1e-26 93.6 40.8 1.3e-26 93.3 40.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GPS2_interact PF15784.5 EAX76335.1 - 0.022 15.2 0.4 0.026 14.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAX76335.1 - 0.037 14.4 1.9 0.038 14.4 1.9 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Trypan_PARP PF05887.11 EAX76337.1 - 0.088 12.8 9.3 0.11 12.5 9.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX76338.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX76338.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PapD_N PF00345.20 EAX76339.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX76341.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX76344.1 - 8.3e-154 510.0 12.8 1e-153 509.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76344.1 - 0.062 13.6 0.5 6.4 7.1 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76344.1 - 0.39 11.2 5.9 1.9 9.0 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX76344.1 - 0.75 10.5 4.9 1.1 9.9 0.1 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX76345.1 - 9.5e-43 144.6 0.0 1.4e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain DUF2939 PF11159.8 EAX76346.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76346.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76346.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX76346.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76347.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Ank_2 PF12796.7 EAX76349.1 - 1.1e-06 29.2 0.0 1.2e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX76349.1 - 1.9e-05 25.1 0.0 2.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX76349.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76349.1 - 0.0051 17.2 0.0 0.058 14.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX76349.1 - 0.078 13.5 0.0 5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DUF4107 PF13389.6 EAX76351.1 - 3.9e-71 238.5 3.5 5.9e-71 237.9 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76351.1 - 0.069 13.5 0.6 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX76352.1 - 2.5e-08 33.9 2.5 2.5e-08 33.9 2.5 3.9 4 0 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX76352.1 - 0.00099 18.8 5.1 0.00099 18.8 5.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX76352.1 - 0.032 14.0 4.4 0.047 13.5 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX76352.1 - 0.055 13.9 0.3 0.28 11.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) DUF4106 PF13388.6 EAX76353.1 - 9.1e-22 77.9 1.3 9.6e-22 77.8 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) FliD_N PF02465.18 EAX76354.1 - 0.19 12.5 4.8 0.26 12.0 4.8 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX76354.1 - 1 8.0 3.9 1.3 7.8 3.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YvrJ PF12841.7 EAX76355.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family DUF4108 PF13390.6 EAX76356.1 - 1.7e-61 206.4 6.9 1.8e-61 206.2 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76357.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX76358.1 - 2.3e-07 30.5 0.6 1.4e-06 28.0 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX76358.1 - 0.055 13.1 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76358.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX76358.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX76359.1 - 1.2e-125 417.9 7.3 1.3e-125 417.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76359.1 - 0.055 13.0 1.4 0.09 12.3 0.3 1.7 1 1 1 2 2 2 0 Z1 domain LD_cluster2 PF18163.1 EAX76359.1 - 0.065 12.8 0.1 0.21 11.1 0.1 1.8 1 1 0 1 1 1 0 SLOG cluster2 Pox_A32 PF04665.12 EAX76361.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76361.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76361.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX76361.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76361.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76361.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76361.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76361.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX76361.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX76361.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76361.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX76361.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX76362.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76362.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX76362.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF4107 PF13389.6 EAX76363.1 - 1.1e-72 243.4 4.2 1.4e-72 243.2 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76363.1 - 0.21 10.0 0.9 0.3 9.4 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX76364.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX76366.1 - 5.1e-08 32.7 0.2 5.1e-08 32.7 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76366.1 - 0.003 18.2 0.1 0.0062 17.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX76367.1 - 5.2e-06 26.1 2.5 5.2e-06 26.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76367.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76367.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX76367.1 - 0.00012 22.1 2.8 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76367.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76367.1 - 0.0013 18.6 0.5 0.0046 16.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76367.1 - 0.0014 18.3 0.4 0.0095 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76367.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX76367.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX76367.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX76367.1 - 0.091 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76367.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX76367.1 - 0.3 11.4 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX76368.1 - 1.5e-271 900.7 40.8 1.3e-144 482.6 11.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76368.1 - 0.0081 16.4 0.1 0.33 11.3 0.2 2.3 2 0 0 2 2 2 1 Kidney androgen-regulated DUF3839 PF12943.7 EAX76369.1 - 4.6e-80 268.6 10.1 6e-80 268.2 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76369.1 - 0.1 12.5 0.8 0.35 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX76370.1 - 3.2e-16 59.2 0.4 1e-15 57.5 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain TMP PF05017.14 EAX76373.1 - 0.062 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76374.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP P22_AR_C PF10548.9 EAX76375.1 - 0.081 13.1 0.2 20 5.4 0.1 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain TMP PF05017.14 EAX76376.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76377.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP MetOD2 PF18548.1 EAX76378.1 - 0.036 14.2 1.0 0.036 14.2 1.0 3.3 2 2 1 3 3 3 0 Metanogen output domain 2 Citrate_bind PF16114.5 EAX76378.1 - 0.15 11.6 0.3 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding BRE1 PF08647.11 EAX76378.1 - 0.18 11.9 12.6 0.075 13.1 1.3 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase NurA PF09376.10 EAX76378.1 - 0.77 9.4 7.8 0.15 11.7 3.1 1.8 1 1 1 2 2 2 0 NurA domain Csm1_N PF18504.1 EAX76378.1 - 4.9 7.6 15.2 2 8.8 2.7 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Amidase02_C PF12123.8 EAX76379.1 - 0.0087 15.7 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX76380.1 - 1.8e-244 811.5 17.5 1.8e-244 811.5 17.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76380.1 - 0.016 15.5 0.1 0.82 10.0 0.1 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated RSS_P20 PF11757.8 EAX76380.1 - 0.58 10.6 8.7 1.1 9.8 3.0 2.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF3839 PF12943.7 EAX76382.1 - 4e-118 393.2 7.4 4.6e-118 393.0 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4106 PF13388.6 EAX76383.1 - 1.7e-218 725.9 20.6 2e-218 725.7 20.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX76383.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Ndc1_Nup PF09531.10 EAX76383.1 - 3.7 6.1 6.8 5.9 5.5 6.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3839 PF12943.7 EAX76384.1 - 5e-116 386.3 6.7 5.8e-116 386.1 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76384.1 - 0.044 13.3 0.7 0.061 12.8 0.6 1.4 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX76384.1 - 0.16 12.6 2.2 0.93 10.2 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX76384.1 - 0.88 9.9 4.5 4.7 7.6 0.1 2.9 2 1 1 3 3 3 0 Rx N-terminal domain DUF3839 PF12943.7 EAX76385.1 - 1.2e-59 201.7 4.2 1.4e-59 201.5 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76385.1 - 0.023 14.2 0.2 0.027 14.0 0.2 1.0 1 0 0 1 1 1 0 Z1 domain MvaI_BcnI PF15515.6 EAX76385.1 - 0.048 13.5 1.1 2.6 7.8 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family FAS_N PF17828.1 EAX76386.1 - 0.0054 16.7 0.2 0.0073 16.3 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX76387.1 - 0.0053 17.2 0.8 0.0061 17.0 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76387.1 - 1.2 9.2 6.9 1.3 9.0 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ank_4 PF13637.6 EAX76389.1 - 1.6e-08 34.9 0.1 8.7e-06 26.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76389.1 - 3.1e-06 27.1 3.0 0.00013 22.1 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAX76389.1 - 3.9e-06 27.1 0.1 0.00063 20.1 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EAX76389.1 - 8.9e-06 26.2 0.2 1.4e-05 25.5 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX76389.1 - 0.00036 20.8 0.1 0.00069 19.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) UCH PF00443.29 EAX76389.1 - 0.059 12.9 0.4 0.077 12.5 0.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3839 PF12943.7 EAX76390.1 - 1.5e-38 132.7 4.6 2.1e-38 132.1 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX76390.1 - 0.079 12.1 0.1 0.096 11.8 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II JMY PF15871.5 EAX76392.1 - 0.021 14.1 0.8 0.032 13.6 0.8 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX76392.1 - 0.52 10.4 2.7 0.64 10.1 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4108 PF13390.6 EAX76393.1 - 3.2e-62 208.7 5.6 3.6e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX76394.1 - 0.032 14.7 0.4 0.061 13.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX76394.1 - 0.42 10.7 3.5 9.1 6.4 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein IKKbetaNEMObind PF12179.8 EAX76395.1 - 0.12 12.4 0.1 0.43 10.7 0.1 1.9 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF515 PF04415.12 EAX76395.1 - 0.13 10.6 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Guanylate_cyc PF00211.20 EAX76396.1 - 1.4e-34 119.3 0.1 1.6e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4106 PF13388.6 EAX76397.1 - 3.2e-280 929.2 20.6 4.8e-280 928.7 20.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76397.1 - 0.019 15.3 0.1 0.86 9.9 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated KilA-N PF04383.13 EAX76398.1 - 8.3e-39 131.9 0.5 2.1e-38 130.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX76398.1 - 0.27 9.8 0.1 0.39 9.2 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Bromodomain PF00439.25 EAX76399.1 - 3.5e-22 78.3 1.3 8.8e-22 77.0 1.3 1.7 1 0 0 1 1 1 1 Bromodomain PTR PF12789.7 EAX76400.1 - 2e-05 24.5 0.6 2e-05 24.5 0.6 3.2 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX76400.1 - 0.0048 16.5 4.1 0.01 15.5 4.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) MpPF1 PF07668.11 EAX76400.1 - 0.0055 16.0 0.5 0.0086 15.4 0.5 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 1 EDR1 PF14381.6 EAX76400.1 - 0.043 13.5 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX76400.1 - 0.063 13.7 0.3 0.26 11.8 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX76400.1 - 0.099 12.4 0.6 0.13 12.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phage_fiber PF03335.13 EAX76400.1 - 6 7.3 9.4 3.4 8.1 0.3 3.5 3 0 0 3 3 3 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX76402.1 - 2.1e-127 423.6 9.1 2.3e-127 423.4 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX76402.1 - 0.061 12.8 0.1 0.2 11.2 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 Z1 PF10593.9 EAX76402.1 - 0.1 12.1 2.0 0.13 11.7 0.7 1.7 1 1 1 2 2 2 0 Z1 domain KELK PF15796.5 EAX76402.1 - 0.13 12.8 2.4 0.63 10.5 1.1 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX76405.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX76405.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX76405.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX76406.1 - 4.9e-09 35.6 1.0 9.1e-09 34.7 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX76406.1 - 0.14 12.2 0.0 0.95 9.5 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Spo12 PF05032.12 EAX76407.1 - 0.21 11.5 5.5 0.17 11.8 2.9 2.1 2 1 0 2 2 2 0 Spo12 family DUF4107 PF13389.6 EAX76409.1 - 2.2e-69 232.8 3.4 2.5e-69 232.5 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76409.1 - 0.099 11.0 1.1 0.13 10.6 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1476 PF07345.11 EAX76409.1 - 0.11 12.8 0.5 0.16 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX76410.1 - 0.024 14.5 1.0 0.04 13.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDE_Tnp_ISL3 PF01610.17 EAX76411.1 - 9.5e-06 25.5 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Transposase Adeno_E1B_55K PF01696.17 EAX76411.1 - 0.017 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Laminin_I PF06008.14 EAX76414.1 - 0.0017 18.1 0.3 0.0022 17.7 0.3 1.0 1 0 0 1 1 1 1 Laminin Domain I Spatacsin_C PF14649.6 EAX76414.1 - 0.015 14.5 0.1 0.015 14.5 0.1 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus RNase_E_G PF10150.9 EAX76414.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Ribonuclease E/G family Sec34 PF04136.15 EAX76414.1 - 0.12 12.2 1.7 0.21 11.5 1.7 1.4 1 0 0 1 1 1 0 Sec34-like family Synaptobrevin PF00957.21 EAX76414.1 - 1.9 8.3 4.5 11 5.9 0.6 2.2 1 1 1 2 2 2 0 Synaptobrevin DNA_pol_B_2 PF03175.13 EAX76416.1 - 1.2e-08 34.3 1.0 1.2e-08 34.3 1.0 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX76416.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX76416.1 - 0.12 12.3 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Zn_peptidase PF04228.13 EAX76418.1 - 0.21 11.0 0.8 2.2 7.6 0.1 2.0 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase DNA_pol_B_2 PF03175.13 EAX76419.1 - 4.6e-23 81.8 3.9 6.6e-23 81.3 3.9 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX76420.1 - 9.9e-29 99.2 22.6 8.4e-24 83.4 6.5 4.5 3 1 0 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX76420.1 - 0.059 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX76420.1 - 0.085 12.6 1.7 3.7 7.2 0.7 2.7 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX76420.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3417) DUF240 PF03086.14 EAX76420.1 - 0.29 11.1 5.5 1.3 9.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAX76420.1 - 2.7 7.6 29.2 1.6e+03 -1.5 25.4 4.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX76420.1 - 3.2 7.5 16.1 24 4.6 14.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PTR PF12789.7 EAX76421.1 - 6.4e-80 263.2 53.5 7.9e-35 118.7 16.6 5.6 2 2 3 5 5 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX76421.1 - 0.037 13.8 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GUN4_N PF16416.5 EAX76421.1 - 0.053 13.5 2.3 6.1 6.9 0.1 3.3 1 1 3 4 4 4 0 ARM-like repeat domain, GUN4-N terminal DUF4106 PF13388.6 EAX76422.1 - 8.9e-223 740.0 13.4 1e-222 739.8 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX76422.1 - 0.054 13.3 0.2 0.097 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) SRP-alpha_N PF04086.13 EAX76422.1 - 0.12 12.2 4.6 0.2 11.5 4.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 EAX76422.1 - 0.37 10.8 14.0 0.47 10.4 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EAX76422.1 - 7.5 7.0 15.0 23 5.3 15.0 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Pox_A32 PF04665.12 EAX76423.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76423.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76423.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76423.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76424.1 - 8.6e-82 274.2 7.7 1e-81 274.0 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX76424.1 - 0.045 13.4 1.4 0.081 12.6 1.4 1.6 1 1 0 1 1 1 0 Proteasome activator pa28 beta subunit Z1 PF10593.9 EAX76424.1 - 0.09 12.3 0.4 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 Z1 domain DUF2547 PF10818.8 EAX76424.1 - 0.11 13.5 0.7 3.7 8.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) PTR PF12789.7 EAX76425.1 - 1.2e-85 281.5 54.0 6.6e-32 109.4 14.3 5.6 2 2 3 5 5 5 4 Phage tail repeat like DUF4116 PF13475.6 EAX76425.1 - 0.031 14.0 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX76425.1 - 0.11 12.0 5.2 0.47 9.9 0.6 2.5 1 1 0 2 2 2 0 RRNA methyltransferase AviRa Peptidase_S66 PF02016.15 EAX76425.1 - 0.14 12.3 0.9 49 4.1 0.1 3.7 2 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain DUF4795 PF16043.5 EAX76425.1 - 1.1 8.9 15.3 2.9 7.4 12.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2939 PF11159.8 EAX76426.1 - 0.0058 17.0 0.7 0.0074 16.7 0.4 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76426.1 - 1.4 7.8 4.0 1.4 7.9 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76426.1 - 4.8 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX76426.1 - 6.8 6.7 7.9 7.5 6.6 7.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX76427.1 - 0.035 14.0 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX76427.1 - 0.12 12.4 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX76428.1 - 6.5e-149 494.0 11.9 7.3e-149 493.8 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76428.1 - 0.064 13.5 0.3 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX76428.1 - 0.13 12.1 0.7 0.44 10.4 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76428.1 - 0.42 11.1 3.9 3.1 8.3 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FliJ PF02050.16 EAX76429.1 - 0.02 15.1 2.2 0.024 14.9 2.2 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Ank_4 PF13637.6 EAX76430.1 - 3.1e-40 136.0 5.5 3.6e-09 37.0 0.0 7.0 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX76430.1 - 4.1e-34 115.5 8.2 2.2e-06 27.8 0.3 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_2 PF12796.7 EAX76430.1 - 5.3e-32 110.3 6.8 1.9e-10 41.2 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX76430.1 - 4.5e-27 93.8 2.4 4.8e-07 29.9 0.0 4.5 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76430.1 - 7.8e-26 87.3 7.9 2.9e-05 24.1 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat PapD_N PF00345.20 EAX76431.1 - 0.045 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX76433.1 - 2e-58 196.4 5.5 2.2e-58 196.3 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76433.1 - 0.006 16.8 0.7 3 8.1 0.1 2.4 2 0 0 2 2 2 2 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX76436.1 - 3.4e-80 269.0 10.0 4.4e-80 268.6 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76436.1 - 0.088 12.7 1.1 0.28 11.0 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX76436.1 - 0.099 13.2 0.3 0.17 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX76438.1 - 1.6e-05 24.8 5.0 1.6e-05 24.8 5.0 6.2 5 2 2 7 7 7 2 Phage tail repeat like DUF4795 PF16043.5 EAX76438.1 - 0.00032 20.4 0.2 0.00032 20.4 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4795) DUF4738 PF15889.5 EAX76438.1 - 0.019 14.8 1.9 0.019 14.8 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) DUF3391 PF11871.8 EAX76438.1 - 0.15 12.6 2.5 0.67 10.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF3839 PF12943.7 EAX76439.1 - 1.5e-118 394.6 8.7 1.7e-118 394.4 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX76440.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX76440.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX76441.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76441.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX76443.1 - 2.8e-29 102.3 6.9 4.9e-29 101.5 6.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5454 PF17535.2 EAX76444.1 - 0.05 13.0 0.2 0.064 12.6 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Gal-bind_lectin PF00337.22 EAX76444.1 - 0.053 13.1 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin PSP PF04046.16 EAX76445.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3819 PF12842.7 EAX76446.1 - 0.65 9.9 3.4 0.74 9.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) S-AdoMet_synt_N PF00438.20 EAX76446.1 - 1.9 9.2 5.5 1.8e+02 2.9 5.5 2.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain TCO89 PF10452.9 EAX76446.1 - 5.5 5.8 16.8 5.9 5.7 16.8 1.0 1 0 0 1 1 1 0 TORC1 subunit TCO89 KilA-N PF04383.13 EAX76448.1 - 1.4e-22 79.7 0.2 1.8e-22 79.3 0.2 1.1 1 0 0 1 1 1 1 KilA-N domain Cullin PF00888.22 EAX76448.1 - 0.024 13.3 0.1 0.025 13.2 0.1 1.0 1 0 0 1 1 1 0 Cullin family DUF3038 PF11237.8 EAX76448.1 - 0.18 11.9 0.1 0.24 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF3839 PF12943.7 EAX76449.1 - 4.9e-157 520.6 12.7 5.6e-157 520.4 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76449.1 - 0.27 11.5 2.9 1.3 9.3 0.1 3.0 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76449.1 - 0.46 11.0 5.9 3.9 8.0 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Chal_sti_synt_N PF00195.19 EAX76450.1 - 0.079 12.4 0.6 0.15 11.5 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX76451.1 - 2.8e-152 505.0 12.6 3.3e-152 504.8 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX76451.1 - 0.11 12.9 0.3 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX76451.1 - 1.4 9.4 5.9 5 7.7 0.4 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX76452.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76453.1 - 0.047 14.2 5.5 6.4 7.9 0.8 3.1 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX76455.1 - 5.9e-63 211.1 5.8 6.6e-63 210.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PSP PF04046.16 EAX76457.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX76458.1 - 5.2e-42 142.2 0.5 1.1e-41 141.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76458.1 - 0.013 16.1 0.1 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX76460.1 - 2.4e-148 492.2 15.5 2.9e-148 491.9 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX76460.1 - 0.32 11.3 1.8 0.87 9.9 0.5 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX76460.1 - 0.34 11.4 6.9 2.3 8.7 1.0 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX76460.1 - 0.48 11.0 5.4 0.74 10.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX76460.1 - 0.51 10.6 3.8 2.8 8.3 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain YtxC PF08812.11 EAX76464.1 - 0.033 13.8 0.0 5 6.7 0.0 2.1 2 0 0 2 2 2 0 YtxC-like family DUF2939 PF11159.8 EAX76465.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76465.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76465.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX76466.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta 2_5_RNA_ligase2 PF13563.6 EAX76468.1 - 0.074 13.0 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily DUF2897 PF11446.8 EAX76469.1 - 9.5 6.2 7.0 0.78 9.7 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76470.1 - 6.2e-64 214.2 6.7 6.9e-64 214.1 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VirE PF05272.11 EAX76471.1 - 2.8e-05 24.0 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX76471.1 - 4.1e-05 24.0 2.0 0.00024 21.5 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3198 PF11433.8 EAX76471.1 - 0.13 12.1 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) PTR PF12789.7 EAX76472.1 - 3.5e-51 171.1 38.5 1.1e-32 111.9 16.8 3.8 4 1 1 5 5 5 2 Phage tail repeat like PapD_N PF00345.20 EAX76474.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Amidase02_C PF12123.8 EAX76475.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX76476.1 - 4.7e-141 468.3 12.3 5.4e-141 468.1 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX76476.1 - 0.082 12.4 0.1 0.43 10.1 0.0 1.8 1 1 1 2 2 2 0 SLOG cluster2 KELK PF15796.5 EAX76476.1 - 0.16 12.5 2.9 0.73 10.3 1.0 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX76476.1 - 0.49 10.7 2.2 2.3 8.5 0.0 2.7 2 1 0 2 2 2 0 Rx N-terminal domain DUF4108 PF13390.6 EAX76477.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76478.1 - 0.38 10.7 3.7 0.81 9.6 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX76479.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) JMY PF15871.5 EAX76480.1 - 0.0082 15.5 0.6 0.011 15.0 0.6 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein MULE PF10551.9 EAX76481.1 - 3.7e-05 24.1 1.8 5.1e-05 23.6 0.5 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX76481.1 - 0.0088 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DNA_pol_B_2 PF03175.13 EAX76482.1 - 5.1e-29 101.5 7.1 9.5e-29 100.6 7.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX76482.1 - 0.0062 16.6 1.4 0.42 10.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5065) JMY PF15871.5 EAX76482.1 - 0.018 14.4 0.3 0.026 13.8 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Amidase02_C PF12123.8 EAX76483.1 - 0.0051 16.5 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX76483.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Gly-zipper_Omp PF13488.6 EAX76485.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX76485.1 - 0.24 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76485.1 - 0.85 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DDE_1 PF03184.19 EAX76487.1 - 2.7e-07 30.4 0.1 3.7e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX76487.1 - 0.01 15.6 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease GPS2_interact PF15784.5 EAX76489.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76489.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain APP_amyloid PF10515.9 EAX76490.1 - 0.099 13.2 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus Pox_D5 PF03288.16 EAX76491.1 - 6.7e-06 26.5 3.0 3.7e-05 24.1 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76491.1 - 0.021 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX76491.1 - 0.059 13.3 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX76492.1 - 2e-64 215.8 7.6 2.2e-64 215.7 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76492.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4107 PF13389.6 EAX76495.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) HAUS-augmin3 PF14932.6 EAX76496.1 - 0.0025 17.4 1.7 0.0032 17.1 1.7 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Filament PF00038.21 EAX76496.1 - 0.019 14.5 5.0 0.024 14.2 5.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Lipoxygenase PF00305.19 EAX76496.1 - 0.03 12.7 0.9 0.037 12.5 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase Arm-DNA-bind_5 PF17293.2 EAX76496.1 - 0.082 13.4 8.8 0.77 10.2 8.8 2.4 1 1 0 1 1 1 0 Arm DNA-binding domain DUF3839 PF12943.7 EAX76497.1 - 4.7e-157 520.7 12.8 5.7e-157 520.4 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76497.1 - 0.064 13.7 1.3 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX76497.1 - 0.16 12.4 7.2 0.73 10.3 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX76497.1 - 5.2 7.4 7.5 12 6.3 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal Ank_2 PF12796.7 EAX76498.1 - 5.4e-14 52.5 0.2 1.3e-07 32.1 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX76498.1 - 1.2e-13 51.3 0.0 6.1e-05 23.5 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76498.1 - 1.9e-08 33.9 0.6 0.00036 20.7 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX76498.1 - 4.9e-08 33.1 0.0 3.8e-06 27.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX76498.1 - 9.3e-07 29.0 0.0 3.6e-05 24.0 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeat Melittin PF01372.17 EAX76498.1 - 0.093 12.7 0.5 5.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Melittin MULE PF10551.9 EAX76499.1 - 1.4e-10 41.4 2.2 5.3e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX76499.1 - 0.0022 18.1 1.1 0.0067 16.5 1.1 1.8 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX76499.1 - 0.0028 16.6 0.3 0.0047 15.8 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Cas_APE2256 PF09651.10 EAX76500.1 - 0.097 12.6 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Amidase02_C PF12123.8 EAX76501.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Ly49 PF08391.10 EAX76502.1 - 0.39 11.1 2.6 0.78 10.1 2.6 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4108 PF13390.6 EAX76503.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX76504.1 - 0.0089 15.7 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1493 PF07377.12 EAX76505.1 - 0.023 15.1 0.5 0.043 14.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX76506.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76507.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ARA70 PF12489.8 EAX76508.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Gly-zipper_Omp PF13488.6 EAX76509.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX76509.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76509.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX76510.1 - 7.2e-39 131.7 25.1 1.2e-20 73.3 10.1 3.9 4 1 1 5 5 5 2 Phage tail repeat like PAXIP1_C PF15364.6 EAX76511.1 - 0.09 13.1 10.1 0.12 12.7 10.1 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Btz PF09405.10 EAX76511.1 - 2.2 8.5 9.7 4.2 7.6 9.7 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF4108 PF13390.6 EAX76512.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX76514.1 - 0.00019 21.0 0.5 0.00023 20.7 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76514.1 - 0.077 12.6 0.0 0.077 12.6 0.0 1.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) PapD_N PF00345.20 EAX76516.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76516.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX76518.1 - 0.056 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX76519.1 - 1.4e-24 86.9 5.0 2.2e-24 86.3 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX76519.1 - 0.02 15.0 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers ZapB PF06005.12 EAX76519.1 - 0.067 13.7 0.7 0.44 11.0 0.1 2.0 1 1 0 2 2 2 0 Cell division protein ZapB T5orf172 PF10544.9 EAX76520.1 - 2.8e-05 24.6 0.1 6.6e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX76521.1 - 0.0043 17.1 0.3 0.0056 16.7 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX76522.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3839 PF12943.7 EAX76525.1 - 1.3e-155 515.9 13.0 1.5e-155 515.7 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX76525.1 - 0.056 13.7 0.7 0.12 12.6 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 Rx_N PF18052.1 EAX76525.1 - 0.1 12.9 0.6 1.7 9.0 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76525.1 - 0.61 10.6 6.1 3.9 8.0 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX76526.1 - 4.8e-36 123.0 1.3 6.7e-36 122.5 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76526.1 - 0.0061 17.2 0.1 0.018 15.7 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX76526.1 - 0.82 9.7 4.7 1.9 8.5 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein HAGH_C PF16123.5 EAX76527.1 - 1.3e-13 51.3 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EAX76527.1 - 1.8e-08 34.7 2.4 3.7e-08 33.6 2.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAX76527.1 - 0.0065 16.0 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PTR PF12789.7 EAX76528.1 - 2e-22 79.0 9.7 6.6e-16 58.1 2.1 5.0 5 1 1 6 6 6 2 Phage tail repeat like Pox_A32 PF04665.12 EAX76530.1 - 4.8e-07 29.5 3.0 4.8e-07 29.5 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX76530.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX76530.1 - 0.00016 21.7 3.0 0.00037 20.5 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX76530.1 - 0.00025 20.8 0.3 0.38 10.5 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX76530.1 - 0.00064 19.5 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76530.1 - 0.0013 18.6 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76530.1 - 0.0015 18.2 0.5 0.0098 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76530.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX76530.1 - 0.07 12.7 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX76530.1 - 0.088 12.3 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX76530.1 - 0.093 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3839 PF12943.7 EAX76531.1 - 1.2e-45 155.9 2.4 1.3e-45 155.7 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PcfK PF14058.6 EAX76533.1 - 0.17 12.1 8.0 0.26 11.6 8.0 1.1 1 0 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX76534.1 - 1.4e-42 145.0 3.9 1.5e-42 144.9 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX76534.1 - 0.12 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DNA_pol_B_2 PF03175.13 EAX76537.1 - 3e-08 33.0 0.6 5.3e-08 32.2 0.3 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Ribosomal_S6e PF01092.19 EAX76537.1 - 0.022 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e DNA_pol_B PF00136.21 EAX76537.1 - 0.032 13.0 3.0 0.45 9.2 2.8 2.1 1 1 0 1 1 1 0 DNA polymerase family B DUF3839 PF12943.7 EAX76538.1 - 1.8e-155 515.5 11.7 2.2e-155 515.2 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76538.1 - 0.07 13.6 1.9 0.2 12.1 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX76538.1 - 0.11 13.0 7.0 0.69 10.4 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX76538.1 - 0.12 12.2 1.7 0.3 10.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX76538.1 - 0.92 10.1 6.5 0.33 11.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX76539.1 - 8e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX76539.1 - 0.093 13.2 0.5 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX76540.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76540.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76540.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76540.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MG2 PF01835.19 EAX76541.1 - 1.2e-06 28.9 1.1 0.0061 17.0 0.1 3.4 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX76541.1 - 2e-05 24.8 3.4 0.03 14.6 0.1 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX76541.1 - 0.0099 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain NPCBM_assoc PF10633.9 EAX76541.1 - 0.016 15.5 5.5 0.084 13.1 0.2 3.9 3 2 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase He_PIG PF05345.12 EAX76541.1 - 0.019 15.2 1.9 0.32 11.2 0.1 3.6 3 0 0 3 3 3 0 Putative Ig domain DUF3324 PF11797.8 EAX76541.1 - 0.026 14.5 1.0 0.5 10.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) bMG6 PF17962.1 EAX76541.1 - 0.052 13.7 1.1 5.2 7.3 0.1 3.2 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 DUF2914 PF11141.8 EAX76541.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) PKD PF00801.20 EAX76541.1 - 0.082 12.8 0.1 0.65 9.9 0.0 2.6 2 0 0 2 2 2 0 PKD domain RIFIN PF02009.16 EAX76541.1 - 0.14 12.1 6.4 0.19 11.6 6.4 1.2 1 0 0 1 1 1 0 Rifin ARA70 PF12489.8 EAX76542.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Frigida PF07899.11 EAX76543.1 - 0.087 12.1 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein Pox_A32 PF04665.12 EAX76544.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76544.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76544.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76544.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76545.1 - 2.9e-75 252.8 8.3 3.8e-75 252.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX76546.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX76548.1 - 1.3e-05 25.3 1.3 2.4e-05 24.4 1.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76548.1 - 0.00036 20.4 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX76548.1 - 0.00047 20.4 0.0 0.00071 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX76548.1 - 0.0019 18.1 0.2 0.003 17.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76548.1 - 0.0032 17.8 0.0 0.0042 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX76548.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76548.1 - 0.084 12.3 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX76548.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX76548.1 - 0.16 11.7 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX76548.1 - 0.22 11.1 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 EAX76549.1 - 1e-29 103.7 6.6 1.9e-29 102.9 6.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76549.1 - 0.024 13.9 0.5 0.039 13.3 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5106 PF17127.4 EAX76549.1 - 0.028 14.7 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF5065 PF16723.5 EAX76549.1 - 0.15 12.1 0.5 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DNA_pol_B_2 PF03175.13 EAX76550.1 - 8.4e-23 81.0 3.7 1.2e-22 80.5 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX76551.1 - 7.9e-80 267.8 10.5 1e-79 267.4 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76551.1 - 0.1 12.4 0.9 0.33 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX76553.1 - 4.3e-41 139.3 1.1 7.5e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX76554.1 - 2e-130 433.5 6.8 2.3e-130 433.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX76555.1 - 9.8e-15 54.4 0.1 1.9e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76555.1 - 0.022 14.7 1.4 0.16 12.0 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NTS PF15447.6 EAX76555.1 - 0.37 11.3 3.2 2.9 8.5 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX76556.1 - 1e-141 470.4 9.2 1.2e-141 470.2 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76556.1 - 0.078 12.8 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX76556.1 - 0.2 11.9 2.7 1 9.7 0.0 2.8 2 1 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX76556.1 - 0.24 11.9 1.5 1.2 9.6 0.6 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AbrB_C PF18277.1 EAX76557.1 - 0.046 13.4 0.2 69 3.2 0.0 3.2 3 0 0 3 3 3 0 AbrB C-terminal domain DUF4210 PF13915.6 EAX76557.1 - 0.12 13.0 0.0 18 6.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4210) Helicase_C PF00271.31 EAX76558.1 - 5.1e-06 26.8 2.1 2.3e-05 24.7 2.1 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain RRM_occluded PF16842.5 EAX76558.1 - 0.05 13.5 0.1 0.77 9.7 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif KilA-N PF04383.13 EAX76559.1 - 7e-42 141.8 0.6 1.4e-41 140.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76559.1 - 0.047 14.3 0.1 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX76560.1 - 2.9e-06 27.8 0.2 5.8e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1731 PF08338.11 EAX76561.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX76562.1 - 1.8e-07 30.8 0.6 1.5e-06 27.9 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX76562.1 - 0.021 14.4 0.1 0.76 9.4 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76562.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX76562.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX76563.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX76563.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76563.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX76563.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4106 PF13388.6 EAX76564.1 - 3.6e-246 817.1 30.1 1.2e-245 815.3 30.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) TFIIA PF03153.13 EAX76564.1 - 5.9 6.8 36.0 0.36 10.8 21.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4107 PF13389.6 EAX76565.1 - 3.8e-72 241.7 3.6 5e-72 241.4 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX76567.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX76567.1 - 0.18 11.7 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) TMP PF05017.14 EAX76568.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76569.1 - 0.072 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX76571.1 - 5.2e-111 369.9 7.4 6.1e-111 369.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_4 PF13637.6 EAX76573.1 - 2.7e-12 46.9 1.3 1.8e-06 28.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX76573.1 - 7.5e-11 42.5 0.2 7.9e-11 42.4 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX76573.1 - 2.8e-07 30.7 0.2 3.5e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX76573.1 - 1.6e-06 28.2 3.5 4.3e-05 23.8 0.2 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX76573.1 - 5.6e-06 26.3 0.1 5e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Gly-zipper_Omp PF13488.6 EAX76574.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX76574.1 - 0.64 10.3 5.9 1.1 9.6 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PSP PF04046.16 EAX76577.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76578.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX76579.1 - 3.2e-05 24.4 0.3 9.5e-05 22.9 0.3 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX76579.1 - 0.0097 15.5 1.2 0.13 11.7 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX76579.1 - 0.011 15.6 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX76580.1 - 3.1e-27 95.6 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX76580.1 - 0.18 12.2 0.9 0.76 10.3 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB APC_u14 PF16635.5 EAX76580.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr PTR PF12789.7 EAX76581.1 - 8.5e-64 211.5 44.5 2.4e-31 107.6 14.1 5.1 2 2 3 5 5 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX76581.1 - 0.025 14.3 0.1 0.11 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YidD PF01809.18 EAX76582.1 - 3.2 7.7 18.5 5.3 7.0 0.4 5.5 2 1 4 6 6 6 0 Putative membrane protein insertion efficiency factor DUF3839 PF12943.7 EAX76583.1 - 9e-158 523.0 12.1 1.1e-157 522.7 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76583.1 - 0.053 14.0 2.0 0.11 13.0 0.3 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX76583.1 - 0.088 13.1 1.6 12 6.3 0.1 3.7 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX76583.1 - 0.4 11.2 6.0 1.9 9.0 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX76584.1 - 3.1e-62 208.7 6.0 3.5e-62 208.6 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76585.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX76586.1 - 2.1e-05 24.6 1.0 3.5e-05 23.9 1.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76586.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX76586.1 - 0.0004 20.7 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX76586.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76586.1 - 0.0068 16.7 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76586.1 - 0.034 13.6 0.0 0.074 12.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX76586.1 - 0.058 13.0 0.4 0.094 12.4 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX76586.1 - 0.072 12.8 0.0 0.099 12.4 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX76586.1 - 0.099 12.2 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX76586.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Vac_Fusion PF02346.16 EAX76586.1 - 0.33 10.6 3.6 7.4 6.3 0.1 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 APG12 PF04110.13 EAX76586.1 - 0.51 10.8 2.7 0.42 11.0 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX76587.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PWI PF01480.17 EAX76588.1 - 0.021 15.1 0.4 0.079 13.3 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF5365 PF17326.2 EAX76588.1 - 0.022 15.2 0.1 0.05 14.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4107 PF13389.6 EAX76590.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4795 PF16043.5 EAX76591.1 - 0.00021 20.9 20.3 0.024 14.2 2.7 3.9 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX76591.1 - 0.12 12.1 0.2 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) RNA12 PF10443.9 EAX76591.1 - 0.13 10.9 8.2 2.7 6.6 8.2 2.2 1 1 0 1 1 1 0 RNA12 protein RlmM_FDX PF18125.1 EAX76591.1 - 0.29 11.6 2.1 4.9 7.7 0.4 2.6 1 1 1 2 2 2 0 RlmM ferredoxin-like domain Topo_Zn_Ribbon PF08272.11 EAX76591.1 - 0.61 9.8 13.2 28 4.5 0.2 5.3 1 1 5 6 6 6 0 Topoisomerase I zinc-ribbon-like DUF809 PF05663.11 EAX76591.1 - 1.1 9.3 5.2 7.4 6.7 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF809) DUF4107 PF13389.6 EAX76592.1 - 1.7e-54 184.4 16.5 9e-53 178.8 16.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76592.1 - 0.088 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX76593.1 - 1.8e-41 140.5 1.3 2.3e-41 140.1 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76593.1 - 0.0044 17.6 0.1 0.015 15.9 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family ABC1 PF03109.16 EAX76593.1 - 0.043 14.0 1.0 1 9.6 0.1 2.6 1 1 1 2 2 2 0 ABC1 family DUF1493 PF07377.12 EAX76594.1 - 0.01 16.3 0.4 0.019 15.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX76595.1 - 2.1e-08 34.1 2.5 2.1e-08 34.1 2.5 4.0 3 1 1 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX76595.1 - 0.003 17.2 4.6 0.003 17.2 4.6 3.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) MeaB PF03308.16 EAX76595.1 - 0.17 10.8 1.2 0.27 10.2 0.9 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX76595.1 - 0.25 11.8 0.1 0.25 11.8 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX76595.1 - 0.31 10.8 12.3 0.46 10.3 12.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2939 PF11159.8 EAX76596.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76596.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76597.1 - 0.0064 16.5 0.2 0.0086 16.1 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX76598.1 - 1e-36 125.2 1.9 1e-36 125.2 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX76598.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FTHFS PF01268.19 EAX76599.1 - 0.3 9.2 0.0 0.36 9.0 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DNA_pol_B_2 PF03175.13 EAX76600.1 - 5.4e-29 101.4 7.2 9.3e-29 100.6 7.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76600.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein KilA-N PF04383.13 EAX76601.1 - 2.9e-42 143.1 1.2 4.1e-42 142.6 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76601.1 - 0.0062 17.1 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family DUF3839 PF12943.7 EAX76602.1 - 5.3e-148 491.0 12.1 6.2e-148 490.8 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX76602.1 - 0.11 12.0 0.1 0.47 9.9 0.1 1.9 1 1 1 2 2 2 0 SLOG cluster2 Rx_N PF18052.1 EAX76602.1 - 0.36 11.1 2.2 1.5 9.1 0.0 2.7 2 1 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX76602.1 - 0.92 10.0 4.1 1.6 9.3 0.9 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX76605.1 - 6.2e-10 39.0 2.3 6.2e-10 39.0 2.3 2.6 2 2 0 2 2 2 1 Phage tail repeat like DUF2175 PF09943.9 EAX76605.1 - 0.063 13.6 1.1 0.48 10.7 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4795 PF16043.5 EAX76605.1 - 0.086 12.4 2.1 0.32 10.6 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4087 PF13316.6 EAX76605.1 - 0.11 12.9 0.2 0.25 11.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4087) EpuA PF11772.8 EAX76606.1 - 0.0068 16.1 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta DUF1947 PF09183.10 EAX76606.1 - 0.024 14.9 1.0 0.12 12.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) KilA-N PF04383.13 EAX76610.1 - 7e-23 80.6 0.3 1.3e-22 79.7 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76610.1 - 0.04 13.9 0.7 0.16 12.0 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX76610.1 - 0.24 10.8 0.6 1.1 8.6 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Ank_2 PF12796.7 EAX76611.1 - 1e-179 583.7 13.2 2e-17 63.5 0.0 8.0 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX76611.1 - 1.9e-103 337.6 1.3 2.1e-13 50.5 0.0 10.2 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX76611.1 - 7.8e-100 323.4 0.1 1.1e-06 28.8 0.0 13.8 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 EAX76611.1 - 6.1e-97 316.4 16.0 9e-11 41.8 0.0 13.0 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76611.1 - 3.2e-82 260.6 0.0 1.7e-05 24.8 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat PilZ_2 PF16823.5 EAX76611.1 - 5.1e-07 29.9 0.0 1.1 9.5 0.0 4.5 1 1 2 5 5 5 3 Atypical PilZ domain, cyclic di-GMP receptor FBD PF08387.10 EAX76611.1 - 1.2e-05 25.0 0.0 51 3.9 0.0 8.3 9 3 1 10 10 10 0 FBD DUF1897 PF09005.10 EAX76611.1 - 0.00016 21.1 0.7 62 3.2 0.0 8.2 12 0 0 12 12 12 0 Domain of unknown function (DUF1897) DUF3083 PF11281.8 EAX76611.1 - 0.0014 18.1 0.2 11 5.3 0.0 4.7 1 1 1 4 4 4 1 Protein of unknown function (DUF3083) DUF2689 PF10894.8 EAX76611.1 - 0.0018 18.0 0.0 82 3.1 0.0 7.1 10 0 0 10 10 10 0 Protein of unknown function (DUF2689) Pox_E8 PF03394.13 EAX76611.1 - 0.0026 17.3 9.1 41 3.6 0.1 8.3 3 2 8 11 11 11 0 Poxvirus E8 protein DUF2795 PF11387.8 EAX76611.1 - 0.0067 16.6 6.3 2.8e+02 1.8 0.0 7.8 8 0 0 8 8 8 0 Protein of unknown function (DUF2795) LRR_5 PF13306.6 EAX76613.1 - 9.4e-67 222.8 72.6 1.7e-24 86.2 16.3 4.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX76613.1 - 2.1e-16 59.4 23.0 0.011 15.4 0.2 9.6 4 2 7 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 EAX76613.1 - 2.4 8.7 53.2 0.35 11.4 0.3 9.4 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) Laminin_I PF06008.14 EAX76615.1 - 1.6e-12 47.7 30.6 0.0019 17.9 1.8 4.6 1 1 5 6 6 6 6 Laminin Domain I KASH_CCD PF14662.6 EAX76615.1 - 2e-10 40.8 27.7 5.8e-05 23.0 9.6 2.1 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX76615.1 - 9.2e-06 25.2 15.2 0.71 9.2 0.8 5.0 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) BLOC1_2 PF10046.9 EAX76615.1 - 4.1e-05 23.8 23.0 0.91 9.9 2.1 5.5 1 1 3 4 4 4 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 EAX76615.1 - 7.4e-05 22.7 15.0 0.12 12.2 2.2 3.2 1 1 3 4 4 4 4 Ezrin/radixin/moesin family ZapB PF06005.12 EAX76615.1 - 0.0001 22.7 16.3 11 6.5 3.6 5.5 1 1 3 4 4 4 0 Cell division protein ZapB UPF0449 PF15136.6 EAX76615.1 - 0.00021 21.7 26.5 1.5 9.3 2.4 5.7 1 1 4 5 5 5 1 Uncharacterised protein family UPF0449 YabA PF06156.13 EAX76615.1 - 0.00028 21.5 9.6 14 6.4 3.2 4.8 1 1 2 3 3 3 0 Initiation control protein YabA Sec34 PF04136.15 EAX76615.1 - 0.00048 20.0 51.0 0.83 9.5 3.3 6.0 1 1 5 6 6 6 5 Sec34-like family BRE1 PF08647.11 EAX76615.1 - 0.0012 18.8 25.7 1.2 9.2 3.0 4.2 1 1 2 4 4 4 4 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 EAX76615.1 - 0.002 17.0 27.0 0.25 10.2 1.8 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein JIP_LZII PF16471.5 EAX76615.1 - 0.0023 18.1 13.7 13 6.0 0.2 6.5 1 1 6 7 7 7 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 EAX76615.1 - 0.0031 16.9 49.1 0.12 11.6 11.1 3.2 1 1 1 3 3 3 3 Protein of unknown function (DUF3450) CheZ PF04344.13 EAX76615.1 - 0.0082 16.1 22.8 0.069 13.1 4.8 3.2 1 1 2 3 3 3 2 Chemotaxis phosphatase, CheZ DUF1664 PF07889.12 EAX76615.1 - 0.015 15.3 15.6 1.4 9.0 1.5 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 EAX76615.1 - 0.017 15.4 29.5 9.3 6.5 5.5 4.1 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 EAX76615.1 - 0.017 15.1 28.9 0.82 9.7 3.4 3.9 1 1 4 5 5 5 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EAX76615.1 - 0.055 13.5 47.4 0.056 13.5 15.2 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4795 PF16043.5 EAX76615.1 - 0.13 11.8 28.9 1.4 8.5 0.5 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Tropomyosin_1 PF12718.7 EAX76615.1 - 0.22 11.7 15.5 7.6 6.7 2.2 3.7 1 1 2 3 3 3 0 Tropomyosin like APG6_N PF17675.1 EAX76615.1 - 0.28 11.7 33.6 8.5 6.9 8.6 3.6 1 1 1 2 2 1 0 Apg6 coiled-coil region PI_PP_I PF18363.1 EAX76615.1 - 0.54 10.5 8.9 35 4.7 0.2 4.0 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain COG7 PF10191.9 EAX76615.1 - 0.57 8.4 37.0 0.055 11.7 7.0 4.0 1 1 3 4 4 4 0 Golgi complex component 7 (COG7) TACC_C PF05010.14 EAX76615.1 - 0.88 9.3 13.2 1.8 8.3 3.8 3.4 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cluap1 PF10234.9 EAX76615.1 - 1 8.7 33.8 0.52 9.7 12.8 2.9 1 1 2 3 3 3 0 Clusterin-associated protein-1 Fib_alpha PF08702.10 EAX76615.1 - 1.1 9.5 21.8 1.5 9.0 1.8 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 EAX76615.1 - 1.2 8.9 18.3 7.2 6.4 3.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 EAX76615.1 - 1.4 9.5 38.4 1.8e+04 -21.4 38.4 4.8 1 1 0 1 1 0 0 Syntaxin 6, N-terminal Prominin PF05478.11 EAX76615.1 - 2.3 6.1 29.8 3.5 5.5 2.9 3.1 1 1 2 3 3 3 0 Prominin Occludin_ELL PF07303.13 EAX76615.1 - 2.5 8.9 10.7 45 4.8 0.1 4.5 1 1 4 5 5 5 0 Occludin homology domain CENP-F_leu_zip PF10473.9 EAX76615.1 - 4.3 7.3 21.7 2.4 8.2 4.0 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRR7 PF12095.8 EAX76615.1 - 4.5 7.8 19.5 11 6.6 0.8 6.2 1 1 7 8 8 8 0 Protein CHLORORESPIRATORY REDUCTION 7 TMPIT PF07851.13 EAX76615.1 - 4.6 6.4 29.5 18 4.4 3.6 3.6 1 1 1 2 2 1 0 TMPIT-like protein PI3K_P85_iSH2 PF16454.5 EAX76615.1 - 6.2 6.4 19.7 2.4e+02 1.2 7.8 4.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5082 PF16888.5 EAX76615.1 - 8.5 6.7 36.7 7.2 6.9 12.7 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Mito_fiss_reg PF05308.11 EAX76616.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX76616.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMP PF05017.14 EAX76617.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX76618.1 - 0.035 14.6 0.6 0.088 13.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX76618.1 - 1.6 8.8 4.8 20 5.3 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX76619.1 - 2e-40 136.7 28.4 1e-23 83.1 6.8 4.6 3 1 0 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX76619.1 - 0.011 15.4 0.1 0.034 13.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX76619.1 - 1.1 9.2 10.7 1.7 8.6 1.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAX76619.1 - 2.7 7.5 19.5 0.84 9.2 7.9 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4887 PF16228.5 EAX76620.1 - 0.071 13.3 2.7 0.086 13.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Meiosis_expr PF15163.6 EAX76621.1 - 0.05 14.3 1.4 0.06 14.0 0.6 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX76621.1 - 1.5 8.8 11.0 0.17 11.8 2.9 3.0 4 0 0 4 4 4 0 Spo12 family PTR PF12789.7 EAX76622.1 - 1.7e-09 37.6 9.7 1.4e-08 34.7 4.8 4.8 5 1 1 6 6 6 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX76622.1 - 0.0045 17.0 5.0 1.3 8.9 1.1 3.4 2 1 1 3 3 3 1 emp24/gp25L/p24 family/GOLD Ribosomal_S4e PF00900.20 EAX76622.1 - 0.094 12.6 0.1 30 4.6 0.0 2.8 2 0 0 2 2 2 0 Ribosomal family S4e KinB_sensor PF16767.5 EAX76622.1 - 0.39 11.2 2.4 5.6 7.5 0.3 2.6 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB IL2 PF00715.17 EAX76622.1 - 0.89 9.5 4.7 15 5.5 0.1 3.0 2 1 1 3 3 3 0 Interleukin 2 NPV_P10 PF05531.12 EAX76622.1 - 7.7 7.1 6.1 31 5.1 1.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 EAX76625.1 - 0.00042 20.6 3.6 0.049 14.0 0.0 2.4 2 0 0 2 2 2 2 Csm1 N-terminal domain DHR10 PF18595.1 EAX76625.1 - 0.0032 17.5 8.5 0.078 13.0 8.3 2.0 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain PKcGMP_CC PF16808.5 EAX76625.1 - 0.0074 16.1 4.1 0.012 15.5 1.1 2.5 1 1 2 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX76625.1 - 0.019 15.3 3.3 0.029 14.7 3.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 EAX76625.1 - 0.02 15.3 3.3 0.033 14.5 3.3 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 EAX76625.1 - 0.034 13.5 4.3 0.037 13.4 4.3 1.1 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 EAX76625.1 - 0.055 12.6 3.3 0.055 12.5 3.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CT_C_D PF02682.16 EAX76625.1 - 0.064 13.0 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D bZIP_1 PF00170.21 EAX76625.1 - 0.12 12.4 4.6 9.9 6.4 3.5 2.4 2 1 0 2 2 2 0 bZIP transcription factor ATG16 PF08614.11 EAX76625.1 - 0.34 11.1 9.4 0.45 10.7 9.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1892 PF08987.10 EAX76626.1 - 0.00036 20.7 0.3 0.97 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1892) BTRD1 PF17660.1 EAX76626.1 - 0.004 16.9 0.0 5 7.0 0.0 2.7 2 0 0 2 2 2 2 Bacterial tandem repeat domain 1 AAA PF00004.29 EAX76626.1 - 0.018 15.5 0.1 7.8 6.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HlyC PF02794.16 EAX76626.1 - 0.047 13.6 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 RTX toxin acyltransferase family SCVP PF17619.2 EAX76626.1 - 0.57 11.1 3.6 3.6 8.5 0.0 2.8 4 0 0 4 4 4 0 Secreted clade V proteins DUF4106 PF13388.6 EAX76629.1 - 2.5e-132 442.1 17.6 4.4e-132 441.3 17.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KilA-N PF04383.13 EAX76630.1 - 3.1e-23 81.8 0.4 4.2e-23 81.3 0.4 1.2 1 0 0 1 1 1 1 KilA-N domain NTS PF15447.6 EAX76630.1 - 0.028 14.9 0.6 0.067 13.7 0.6 1.6 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 Tox-GHH PF15636.6 EAX76630.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF5365 PF17326.2 EAX76631.1 - 0.02 15.3 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4108 PF13390.6 EAX76633.1 - 1.9e-59 199.7 7.8 2.1e-59 199.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX76634.1 - 4.7e-43 146.6 5.0 5.1e-43 146.4 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX76635.1 - 5.1e-05 23.7 3.6 0.00037 20.9 3.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76635.1 - 0.061 13.9 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX76635.1 - 0.072 13.1 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX76636.1 - 8.5e-48 161.9 8.4 9.4e-48 161.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX76638.1 - 1.4e-52 178.6 2.9 1.6e-52 178.4 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76638.1 - 0.069 12.6 0.1 0.076 12.5 0.1 1.0 1 0 0 1 1 1 0 Z1 domain Pox_A32 PF04665.12 EAX76639.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76639.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76639.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76639.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76641.1 - 3.3e-128 426.2 7.7 3.8e-128 426.0 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX76641.1 - 0.049 13.1 1.4 0.074 12.5 1.4 1.5 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX76641.1 - 0.095 13.2 2.2 0.54 10.8 1.1 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX76641.1 - 0.61 10.4 2.5 2.7 8.3 0.0 2.7 2 1 1 3 3 3 0 Rx N-terminal domain Spo12 PF05032.12 EAX76642.1 - 0.52 10.3 8.3 0.18 11.7 2.9 2.5 3 0 0 3 3 3 0 Spo12 family GPS2_interact PF15784.5 EAX76643.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76643.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX76644.1 - 0.058 13.4 7.4 0.082 12.9 7.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX76644.1 - 5.3 7.5 7.0 7.9 6.9 7.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adaptin_N PF01602.20 EAX76645.1 - 4.5e-07 28.8 2.2 5.4e-07 28.5 2.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Arm PF00514.23 EAX76645.1 - 0.00011 22.1 0.0 0.049 13.7 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAX76645.1 - 0.00056 20.0 2.3 0.0011 19.0 2.3 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EAX76645.1 - 0.012 15.7 1.1 0.028 14.5 0.5 1.8 2 1 0 2 2 2 0 V-ATPase subunit H HEAT_EZ PF13513.6 EAX76645.1 - 0.017 15.6 0.0 0.63 10.6 0.0 2.7 2 1 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 EAX76645.1 - 0.033 14.6 0.1 5.4 7.5 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats PapD_N PF00345.20 EAX76647.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX76648.1 - 3.1e-06 26.8 0.6 3.6e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX76648.1 - 0.036 14.4 0.6 0.036 14.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX76649.1 - 1.1e-140 467.0 10.7 1.3e-140 466.9 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76649.1 - 0.12 12.6 2.0 0.8 10.0 0.0 2.7 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76649.1 - 0.19 12.2 3.4 1.1 9.7 1.4 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX76650.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76650.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76651.1 - 0.0057 16.7 0.2 0.0076 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX76652.1 - 2.1e-07 30.7 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76652.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76652.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76652.1 - 0.059 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX76652.1 - 0.41 10.9 8.5 5.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX76653.1 - 1.3e-63 213.1 6.0 1.5e-63 213.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76655.1 - 1.2 9.1 3.2 2.3 8.2 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76656.1 - 1.3e-62 210.0 5.9 1.4e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX76658.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX76660.1 - 5.1e-25 88.3 7.3 9.9e-25 87.3 7.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76660.1 - 0.03 13.7 0.4 0.046 13.0 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Meiosis_expr PF15163.6 EAX76661.1 - 0.061 14.0 2.0 0.069 13.8 0.9 1.6 2 0 0 2 2 2 0 Meiosis-expressed Baculo_LEF-11 PF06385.12 EAX76661.1 - 0.18 12.3 3.3 0.19 12.3 1.9 1.6 1 1 1 2 2 2 0 Baculovirus LEF-11 protein DUF3839 PF12943.7 EAX76662.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX76663.1 - 2.1e-07 30.7 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76663.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76663.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76663.1 - 0.059 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX76663.1 - 0.41 10.9 8.5 5.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3781 PF12636.7 EAX76667.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4108 PF13390.6 EAX76668.1 - 4e-77 257.0 11.7 4.6e-77 256.8 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAX76668.1 - 0.42 11.6 3.1 1 10.4 3.1 1.6 1 0 0 1 1 1 0 Deacetylase PdaC DUF3839 PF12943.7 EAX76670.1 - 7e-156 516.8 12.2 8.9e-156 516.5 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX76670.1 - 0.058 13.7 0.6 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Tup N-terminal NTP_transf_6 PF06042.11 EAX76670.1 - 0.12 12.2 0.8 0.43 10.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76670.1 - 0.27 11.7 2.0 5.3 7.6 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX76671.1 - 2.6e-51 173.3 3.3 2.9e-51 173.2 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX76675.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HNH_3 PF13392.6 EAX76677.1 - 4.4e-07 29.6 0.1 1.1e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Tim54 PF11711.8 EAX76677.1 - 0.0013 17.6 1.0 0.0016 17.3 1.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.12 EAX76677.1 - 0.0025 17.3 6.1 0.0038 16.7 6.1 1.4 1 0 0 1 1 1 1 SDA1 Dymeclin PF09742.9 EAX76677.1 - 0.0031 16.0 4.7 0.013 14.0 3.9 1.8 1 1 1 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein Baculo_PEP_C PF04513.12 EAX76677.1 - 0.0036 17.4 2.1 0.0036 17.4 2.1 1.6 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Na_trans_assoc PF06512.13 EAX76677.1 - 0.0064 16.8 3.0 0.0081 16.5 3.0 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated RNA_pol_3_Rpc31 PF11705.8 EAX76677.1 - 0.0097 16.2 8.6 0.013 15.8 8.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HsdM_N PF12161.8 EAX76677.1 - 0.0099 16.5 9.6 0.018 15.7 3.6 2.3 2 0 0 2 2 2 1 HsdM N-terminal domain CobT PF06213.12 EAX76677.1 - 0.012 15.0 6.6 0.015 14.7 6.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 EAX76677.1 - 0.015 14.7 15.4 0.019 14.4 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 EAX76677.1 - 0.028 14.6 0.5 0.034 14.3 0.5 1.2 1 0 0 1 1 1 0 DDHD domain Mlh1_C PF16413.5 EAX76677.1 - 0.031 13.7 4.3 0.039 13.3 4.3 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus TRAP_alpha PF03896.16 EAX76677.1 - 0.07 12.3 6.6 0.11 11.7 6.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EAX76677.1 - 0.074 12.4 8.6 0.11 11.8 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EAX76677.1 - 0.1 12.2 8.2 0.2 11.3 8.2 1.4 1 0 0 1 1 1 0 FAM176 family RPA43_OB PF17875.1 EAX76677.1 - 0.27 11.9 3.2 0.5 11.0 3.2 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RPN2_C PF18004.1 EAX76677.1 - 0.27 11.1 7.9 0.5 10.3 7.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CAC1F_C PF16885.5 EAX76677.1 - 0.29 10.8 5.5 0.039 13.6 1.2 1.6 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term PI3K_1B_p101 PF10486.9 EAX76677.1 - 0.3 8.8 4.6 0.34 8.6 4.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP_sp32 PF07222.12 EAX76677.1 - 0.37 10.2 10.4 0.65 9.4 10.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1840 PF08895.11 EAX76677.1 - 0.4 11.0 10.7 0.21 11.9 7.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) CENP-B_dimeris PF09026.10 EAX76677.1 - 0.74 10.2 14.0 1.3 9.5 14.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Paf1 PF03985.13 EAX76677.1 - 1.3 8.0 17.0 2.1 7.3 17.0 1.3 1 0 0 1 1 1 0 Paf1 DUF740 PF05340.12 EAX76677.1 - 1.4 7.6 7.2 1.5 7.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2052 PF09747.9 EAX76677.1 - 3.6 7.7 21.9 6.7 6.8 21.9 1.5 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) tRNA_bind_2 PF13725.6 EAX76677.1 - 3.9 7.1 12.0 9.2 5.9 6.0 2.1 2 0 0 2 2 2 0 Possible tRNA binding domain E1_dh PF00676.20 EAX76677.1 - 3.9 6.3 6.6 6.7 5.6 6.6 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component AATF-Che1 PF13339.6 EAX76677.1 - 5.3 7.7 9.1 10 6.8 8.7 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2457 PF10446.9 EAX76677.1 - 6.2 5.8 17.2 9.2 5.3 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) U1snRNP70_N PF12220.8 EAX76677.1 - 7.3 7.3 11.0 3.4 8.4 5.5 2.7 3 1 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MRNIP PF15749.5 EAX76677.1 - 7.6 7.3 7.9 0.59 10.9 3.0 1.7 2 0 0 2 2 1 0 MRN-interacting protein DUF4108 PF13390.6 EAX76679.1 - 2.1e-57 193.1 4.0 2.4e-57 192.9 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX76679.1 - 0.11 11.6 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF4108 PF13390.6 EAX76681.1 - 2.3e-63 212.4 6.0 2.6e-63 212.2 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX76683.1 - 2e-05 24.6 0.8 3.5e-05 23.9 0.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76683.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX76683.1 - 0.00039 20.7 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX76683.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76683.1 - 0.0068 16.8 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76683.1 - 0.032 13.7 0.1 0.041 13.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX76683.1 - 0.058 13.1 0.4 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX76683.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX76683.1 - 0.098 12.2 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX76683.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4106 PF13388.6 EAX76684.1 - 3e-207 688.9 20.2 3e-207 688.9 20.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX76684.1 - 0.31 9.6 4.2 0.54 8.8 4.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EAX76684.1 - 3.4 7.6 5.2 1.2 9.1 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Pex14_N PF04695.13 EAX76687.1 - 5.8 7.6 10.9 6.4 7.4 10.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3839 PF12943.7 EAX76689.1 - 1.6e-156 518.9 13.6 1.9e-156 518.6 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76689.1 - 0.1 12.9 0.3 2.2 8.6 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX76689.1 - 0.39 11.2 5.3 4.8 7.7 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX76689.1 - 0.59 10.7 5.3 0.86 10.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX76691.1 - 1.9e-07 30.8 0.5 1.7e-06 27.7 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX76691.1 - 0.046 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX76691.1 - 0.056 13.1 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76691.1 - 0.064 13.1 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_22 PF13401.6 EAX76693.1 - 1.9e-05 24.9 0.2 0.00015 22.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76693.1 - 2.2e-05 24.3 0.3 0.31 10.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX76693.1 - 0.00011 22.2 3.8 0.00024 21.2 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76693.1 - 0.00035 20.4 0.1 0.00065 19.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76693.1 - 0.00067 19.5 0.5 0.0015 18.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX76693.1 - 0.00084 18.9 1.9 0.00084 18.9 1.9 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX76693.1 - 0.0017 18.0 0.5 0.01 15.5 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX76693.1 - 0.0098 16.2 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX76693.1 - 0.04 13.5 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX76693.1 - 0.053 13.0 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX76693.1 - 0.055 13.9 0.1 0.48 10.8 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX76693.1 - 0.059 12.8 0.1 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX76693.1 - 0.15 12.3 3.3 7.1 7.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DDR PF08841.10 EAX76695.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX76695.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2897 PF11446.8 EAX76696.1 - 0.39 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76697.1 - 1.1e-57 194.0 4.1 1.2e-57 193.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX76699.1 - 0.058 13.3 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76699.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX76701.1 - 5.4e-07 30.1 0.3 1e-06 29.2 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX76701.1 - 0.14 12.8 0.3 0.38 11.4 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 SRP9-21 PF05486.12 EAX76702.1 - 0.43 11.0 3.6 4.7 7.7 1.6 2.6 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Parathyroid PF01279.17 EAX76704.1 - 0.078 13.6 0.1 0.17 12.5 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX76705.1 - 7.8e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX76705.1 - 0.0061 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX76705.1 - 0.0096 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX76705.1 - 0.052 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 T5orf172 PF10544.9 EAX76706.1 - 4.8e-07 30.3 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76706.1 - 0.053 13.4 2.7 0.16 11.8 0.8 2.5 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX76706.1 - 0.095 12.2 0.8 0.38 10.2 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX76707.1 - 1.1e-41 141.2 0.2 2.7e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76707.1 - 0.033 14.8 0.0 0.09 13.4 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family KilA-N PF04383.13 EAX76708.1 - 8.3e-10 38.5 1.3 1.9e-09 37.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain DUF4795 PF16043.5 EAX76709.1 - 0.006 16.2 1.2 0.013 15.1 1.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) PTR PF12789.7 EAX76710.1 - 1.1e-52 175.9 31.2 5.5e-33 112.8 13.6 4.8 3 2 2 5 5 5 2 Phage tail repeat like DUF3839 PF12943.7 EAX76712.1 - 4.9e-25 88.4 4.4 7e-25 87.9 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX76712.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II T5orf172 PF10544.9 EAX76713.1 - 2.6e-06 27.9 0.2 6.6e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76713.1 - 0.013 15.4 0.1 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX76713.1 - 0.014 14.9 0.9 0.16 11.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF2939 PF11159.8 EAX76714.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76714.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX76715.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX76716.1 - 3.2e-63 211.9 6.3 3.7e-63 211.7 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX76717.1 - 9.8e-07 29.3 0.3 2.6e-06 27.9 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76718.1 - 4.3e-41 139.3 0.0 5.6e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX76719.1 - 1.3e-145 483.2 16.0 1.6e-145 482.9 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX76719.1 - 0.077 13.6 1.0 0.5 11.0 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF29 PF01724.16 EAX76719.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function DUF29 KELK PF15796.5 EAX76719.1 - 3.9 8.0 8.0 1.6 9.3 1.0 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank PF00023.30 EAX76720.1 - 2.6e-33 113.0 1.9 7.3e-08 32.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX76720.1 - 2.5e-30 104.5 2.8 3.7e-13 49.7 0.1 4.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX76720.1 - 1.9e-29 102.1 8.3 1.2e-15 57.8 0.9 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX76720.1 - 3.4e-26 88.4 1.8 1.1e-05 25.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX76720.1 - 3.8e-24 84.4 4.8 2.4e-12 46.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PrpR_N PF06506.11 EAX76720.1 - 0.0022 17.6 0.4 4.2 6.9 0.0 3.7 1 1 2 4 4 4 1 Propionate catabolism activator MetallophosN PF16371.5 EAX76720.1 - 0.0022 18.2 0.2 0.61 10.4 0.1 2.8 1 1 1 2 2 2 1 N terminal of Calcineurin-like phosphoesterase SAB PF04382.13 EAX76720.1 - 0.0028 17.7 5.7 5.4 7.2 0.1 4.0 4 0 0 4 4 4 2 SAB domain PH_8 PF15409.6 EAX76720.1 - 0.095 13.0 0.7 17 5.8 0.1 3.2 1 1 3 4 4 4 0 Pleckstrin homology domain Gly_rich PF12810.7 EAX76721.1 - 1.4e-18 67.7 13.1 1.8e-18 67.4 13.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Pox_D5 PF03288.16 EAX76722.1 - 2.4e-05 24.7 2.5 0.00012 22.5 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76722.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX76723.1 - 2.1e-63 212.5 6.6 2.3e-63 212.4 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76724.1 - 0.37 10.7 2.8 0.83 9.6 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX76725.1 - 9.8e-148 490.1 15.3 1.2e-147 489.8 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76725.1 - 0.042 14.3 3.2 0.079 13.4 0.5 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX76725.1 - 0.15 11.9 1.0 0.53 10.1 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX76725.1 - 0.56 10.5 4.7 0.63 10.4 1.0 2.7 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX76725.1 - 0.65 10.5 6.2 4.3 7.9 0.3 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX76729.1 - 5.8e-53 178.7 7.1 6.3e-53 178.5 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX76731.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76731.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX76732.1 - 1.7e-25 89.9 4.1 2.4e-25 89.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX76733.1 - 1.1e-08 35.5 0.0 1.4e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX76733.1 - 7.1e-06 26.2 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX76733.1 - 8.3e-06 26.3 0.0 1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX76733.1 - 9.6e-06 25.8 0.0 0.0022 18.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX76733.1 - 7.5e-05 22.8 0.0 0.11 13.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat DUF3781 PF12636.7 EAX76734.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX76736.1 - 3.6e-08 33.2 1.2 4.1e-08 33.0 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76736.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76736.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76736.1 - 0.088 12.8 0.3 0.7 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76737.1 - 3.8e-127 422.7 7.7 4.4e-127 422.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX76737.1 - 0.26 11.6 1.3 0.66 10.3 1.3 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit T5orf172 PF10544.9 EAX76738.1 - 1.1e-05 25.9 0.2 2.3e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76739.1 - 1.9e-42 143.6 0.5 4.5e-42 142.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76739.1 - 0.0063 17.1 0.1 0.022 15.4 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX76740.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76740.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76740.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76740.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76741.1 - 2e-155 515.3 13.7 2.4e-155 515.1 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76741.1 - 0.033 14.5 0.9 1.1 9.5 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX76741.1 - 0.14 12.1 1.2 0.41 10.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76741.1 - 0.41 11.1 7.5 1.8 9.1 0.9 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX76741.1 - 0.47 11.1 4.0 0.86 10.3 0.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF2408 PF10303.9 EAX76741.1 - 0.78 10.3 5.1 1.1 9.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX76742.1 - 6.7e-22 77.3 16.0 1.3e-16 60.4 1.9 3.9 4 1 0 4 4 4 2 Phage tail repeat like DUF4738 PF15889.5 EAX76742.1 - 0.059 13.2 2.6 0.15 11.9 2.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) CREPT PF16566.5 EAX76743.1 - 0.032 14.4 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX76743.1 - 0.5 10.6 4.9 0.29 11.3 1.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4107 PF13389.6 EAX76747.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76747.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase TMP PF05017.14 EAX76749.1 - 0.049 14.2 4.6 6 8.0 0.8 2.7 2 0 0 2 2 2 0 TMP repeat Trypan_PARP PF05887.11 EAX76749.1 - 4.6 7.2 8.2 4.8 7.2 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX76750.1 - 0.038 14.4 0.4 0.083 13.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX76751.1 - 0.018 14.7 0.5 0.058 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX76753.1 - 2.1e-25 89.6 4.5 3.3e-25 88.9 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX76754.1 - 4.6e-60 201.7 7.4 5.2e-60 201.5 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76755.1 - 0.56 10.1 2.7 1.2 9.1 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX76756.1 - 5.2e-158 523.8 11.3 6.6e-158 523.4 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX76756.1 - 0.07 12.8 2.3 1.1 9.0 0.1 3.3 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit Tup_N PF08581.10 EAX76756.1 - 0.62 10.4 5.1 13 6.2 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal DUF4108 PF13390.6 EAX76757.1 - 3.2e-63 211.9 5.9 3.6e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX76760.1 - 5.5e-153 507.3 13.6 6.9e-153 507.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX76760.1 - 0.095 13.1 0.3 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX76760.1 - 0.49 10.9 5.9 2 8.9 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX76761.1 - 6.7e-33 112.6 18.3 5.6e-32 109.6 14.3 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4404 PF14357.6 EAX76761.1 - 2.8 8.6 5.3 12 6.6 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) PTR PF12789.7 EAX76763.1 - 3.7e-44 148.6 50.3 2.2e-23 82.0 7.8 6.9 7 2 2 9 9 8 3 Phage tail repeat like DUF5327 PF17261.2 EAX76763.1 - 0.012 16.4 1.7 7.1 7.4 0.6 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5327) DUF4116 PF13475.6 EAX76763.1 - 0.082 12.6 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX76763.1 - 0.34 11.5 6.2 2.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) PH_TFIIH PF08567.11 EAX76763.1 - 0.64 10.4 4.5 42 4.6 0.2 3.9 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF4108 PF13390.6 EAX76765.1 - 6e-64 214.3 5.6 6.7e-64 214.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX76765.1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF4108 PF13390.6 EAX76767.1 - 9.8e-57 190.9 7.3 1.1e-56 190.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76767.1 - 0.11 12.7 0.1 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX76768.1 - 1.3e-05 25.6 3.0 0.0001 22.7 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76768.1 - 0.062 13.9 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX76768.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_D5 PF03288.16 EAX76770.1 - 7.8e-05 23.1 3.3 0.00046 20.6 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX76770.1 - 0.086 12.8 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 EAX76770.1 - 0.092 13.4 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX76771.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PDCD9 PF07147.12 EAX76772.1 - 0.07 12.3 0.7 0.078 12.2 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF2897 PF11446.8 EAX76772.1 - 1.2 9.1 3.8 3.3 7.7 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) YmaF PF12788.7 EAX76773.1 - 0.17 12.4 1.8 5.9 7.5 0.1 2.1 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX76773.1 - 3.6 8.0 8.1 12 6.4 1.8 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat PSP PF04046.16 EAX76774.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76775.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX76777.1 - 1.7e-64 216.1 6.7 1.8e-64 215.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76777.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide JMY PF15871.5 EAX76779.1 - 0.032 13.5 0.7 0.049 12.9 0.7 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3781 PF12636.7 EAX76781.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4106 PF13388.6 EAX76782.1 - 3e-273 906.3 18.7 3.7e-273 906.0 18.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76782.1 - 0.00057 20.1 0.2 0.032 14.5 0.3 2.7 2 0 0 2 2 2 1 Kidney androgen-regulated DUF3839 PF12943.7 EAX76785.1 - 1.3e-157 522.5 12.8 1.7e-157 522.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76785.1 - 0.11 13.0 2.9 0.24 11.8 0.5 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX76785.1 - 0.87 10.1 7.0 2.5 8.6 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX76786.1 - 1.1e-149 496.6 16.4 1.3e-149 496.3 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76786.1 - 0.055 13.9 2.1 0.14 12.6 0.3 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX76786.1 - 0.28 11.0 1.9 0.76 9.6 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX76786.1 - 0.62 10.5 7.8 2 8.9 1.0 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Caskin-tail PF16632.5 EAX76787.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin PTR PF12789.7 EAX76788.1 - 5.1e-25 87.3 24.0 4.5e-23 81.1 2.6 5.7 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX76788.1 - 0.16 11.7 1.0 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX76788.1 - 10 5.7 22.1 0.021 14.4 1.6 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF4108 PF13390.6 EAX76789.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Peptidase_M8 PF01457.16 EAX76790.1 - 2.1e-08 33.3 1.2 3e-08 32.8 1.2 1.5 1 1 0 1 1 1 1 Leishmanolysin Nab1 PF04902.12 EAX76791.1 - 0.017 15.5 1.6 0.021 15.2 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 T5orf172 PF10544.9 EAX76792.1 - 5.4e-07 30.1 0.3 1.1e-06 29.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain VirE PF05272.11 EAX76793.1 - 1.4e-05 25.0 0.1 2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX76793.1 - 0.074 13.4 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 RNA helicase DUF4107 PF13389.6 EAX76794.1 - 2.2e-69 232.8 3.4 2.5e-69 232.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX76794.1 - 0.065 11.7 1.1 0.089 11.2 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1476 PF07345.11 EAX76794.1 - 0.11 12.9 0.9 0.16 12.4 0.1 1.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX76795.1 - 2.9e-31 107.3 9.6 2.9e-31 107.3 9.6 3.3 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX76795.1 - 0.082 12.7 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX76795.1 - 4.8 7.1 8.7 1.9 8.4 0.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF3839 PF12943.7 EAX76797.1 - 1.1e-153 509.7 14.5 1.3e-153 509.4 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX76797.1 - 0.52 10.8 7.5 2.1 8.8 1.0 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX76798.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76798.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76798.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76798.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX76798.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX76798.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX76798.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX76799.1 - 0.0031 18.0 0.1 0.0061 17.1 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76799.1 - 0.0081 16.0 0.5 0.018 14.9 0.5 1.7 1 1 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX76800.1 - 7.7e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX76800.1 - 0.06 13.5 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers ArsC PF03960.15 EAX76801.1 - 0.075 13.1 1.0 0.12 12.4 1.0 1.5 1 1 0 1 1 1 0 ArsC family DUF3839 PF12943.7 EAX76802.1 - 2.4e-78 262.9 10.2 3.2e-78 262.6 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX76803.1 - 0.11 12.4 9.5 0.17 11.9 9.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX76804.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76804.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX76806.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX76809.1 - 2.9e-72 242.1 3.8 3.8e-72 241.7 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX76810.1 - 1.2e-06 29.0 0.0 2.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76810.1 - 0.0016 18.2 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX76811.1 - 8.1e-08 32.0 0.7 9e-08 31.9 0.7 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76811.1 - 0.0079 15.9 0.1 0.0083 15.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX76811.1 - 0.059 13.3 0.4 0.54 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX76811.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol_B_2 PF03175.13 EAX76812.1 - 1e-29 103.8 7.3 1.8e-29 103.0 7.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76812.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX76813.1 - 1.3e-126 420.9 8.4 1.5e-126 420.7 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX76813.1 - 0.072 12.6 0.1 0.5 9.8 0.0 2.0 1 1 1 2 2 2 0 SLOG cluster2 Rx_N PF18052.1 EAX76813.1 - 0.59 10.4 2.7 3 8.2 0.0 2.8 2 1 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX76813.1 - 0.68 10.4 3.8 1.6 9.2 2.0 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX76815.1 - 1.4e-29 103.3 7.6 2.5e-29 102.5 7.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX76815.1 - 0.022 14.1 0.2 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX76815.1 - 0.085 12.9 0.8 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Transposase_mut PF00872.18 EAX76816.1 - 0.0019 17.1 0.4 0.0028 16.6 0.4 1.3 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 EAX76816.1 - 0.026 14.9 0.8 0.19 12.2 0.3 2.4 2 0 0 2 2 2 0 MULE transposase domain Amidase02_C PF12123.8 EAX76817.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX76818.1 - 1.5e-43 147.2 0.5 3.5e-43 146.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX76818.1 - 0.032 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX76819.1 - 4.6e-07 30.3 0.2 9.5e-07 29.3 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX76820.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76820.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76820.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76820.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3209 PF11483.8 EAX76822.1 - 0.086 13.3 0.0 8.3 6.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) RFX_DNA_binding PF02257.15 EAX76823.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX76823.1 - 0.00064 20.2 1.7 0.00098 19.6 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX76823.1 - 0.034 14.1 0.8 0.073 13.1 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX76824.1 - 1.9e-63 212.7 4.9 2.1e-63 212.5 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76825.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76826.1 - 5.6e-63 211.1 6.6 6.3e-63 211.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX76827.1 - 1.9e-157 522.0 15.1 2.4e-157 521.6 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX76827.1 - 0.1 13.0 2.3 0.16 12.4 0.4 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX76827.1 - 0.11 12.0 0.1 0.4 10.2 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX76827.1 - 0.83 10.2 7.6 2.3 8.8 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX76828.1 - 4.2e-08 32.9 0.5 4.7e-08 32.8 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76828.1 - 0.0048 16.5 0.1 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX76828.1 - 0.073 13.0 0.3 0.59 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX76828.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX76829.1 - 8.9e-152 503.4 14.0 1e-151 503.2 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76829.1 - 0.031 14.1 0.4 0.1 12.5 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX76829.1 - 0.14 12.4 2.1 13 6.2 0.0 3.1 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX76829.1 - 0.25 11.8 5.0 1.3 9.5 0.2 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Occludin_ELL PF07303.13 EAX76830.1 - 9.1e-05 23.1 0.9 9.1e-05 23.1 0.9 5.6 2 2 4 6 6 6 3 Occludin homology domain DUF3138 PF11336.8 EAX76830.1 - 0.0045 15.7 0.7 0.0045 15.7 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3138) SF-assemblin PF06705.11 EAX76830.1 - 0.018 14.4 74.0 1.5 8.1 25.0 4.2 1 1 2 3 3 3 0 SF-assemblin/beta giardin DUF4404 PF14357.6 EAX76830.1 - 0.024 15.3 9.1 0.024 15.3 9.1 6.8 2 2 6 8 8 8 0 Domain of unknown function (DUF4404) CENP-K PF11802.8 EAX76830.1 - 0.27 10.8 63.1 0.28 10.7 22.4 3.4 1 1 2 3 3 3 0 Centromere-associated protein K HemX PF04375.14 EAX76830.1 - 0.68 9.2 69.0 2.1 7.6 8.5 5.2 1 1 4 5 5 5 0 HemX, putative uroporphyrinogen-III C-methyltransferase YwqJ-deaminase PF14431.6 EAX76830.1 - 1.6 8.9 11.1 6.7 6.9 2.0 3.1 1 1 0 2 2 2 0 YwqJ-like deaminase Titin_Ig-rpts PF06582.12 EAX76830.1 - 1.7 8.6 5.8 31 4.6 0.2 3.4 3 0 0 3 3 3 0 Titin repeat DUF4140 PF13600.6 EAX76830.1 - 2 8.9 74.3 0.62 10.5 0.7 8.7 2 2 7 9 9 9 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.12 EAX76830.1 - 5.7 5.4 26.5 6.1 5.2 5.5 3.5 1 1 2 3 3 3 0 Fusaric acid resistance protein family Lebercilin PF15619.6 EAX76830.1 - 6.9 6.3 87.3 0.24 11.1 14.6 5.0 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF3781 PF12636.7 EAX76831.1 - 0.023 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX76832.1 - 1.7e-14 53.6 0.1 3.4e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76832.1 - 0.016 15.1 2.3 0.058 13.4 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NTS PF15447.6 EAX76832.1 - 0.35 11.4 3.5 2.9 8.5 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX76833.1 - 1.1e-145 483.4 10.7 1.3e-145 483.2 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX76833.1 - 0.78 10.0 3.3 4.1 7.7 0.0 3.0 2 1 1 3 3 3 0 Rx N-terminal domain AlkA_N PF06029.11 EAX76834.1 - 0.0049 17.1 0.0 16 5.8 0.0 3.4 1 1 1 3 3 3 2 AlkA N-terminal domain DUF4795 PF16043.5 EAX76834.1 - 0.02 14.5 17.6 1.5 8.4 0.5 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF5348 PF17295.2 EAX76834.1 - 0.053 13.4 2.8 18 5.4 0.5 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5348) EpuA PF11772.8 EAX76834.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta IL17_R_N PF15037.6 EAX76834.1 - 0.3 10.0 1.9 1.2 8.0 0.4 2.1 1 1 0 2 2 2 0 Interleukin-17 receptor extracellular region DUF4107 PF13389.6 EAX76835.1 - 5.1e-72 241.3 3.2 7.7e-72 240.7 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX76837.1 - 2.8e-25 89.2 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX76837.1 - 0.057 13.9 0.2 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PRE_C2HC PF07530.11 EAX76837.1 - 0.064 13.4 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF563 PF04577.14 EAX76838.1 - 3.8e-09 37.0 0.2 5.2e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 EAX76839.1 - 0.001 19.2 0.0 0.0011 19.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF563) KilA-N PF04383.13 EAX76840.1 - 1e-33 115.5 1.8 1.1e-33 115.4 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX76841.1 - 1.2e-07 32.2 0.4 2.5e-07 31.2 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX76841.1 - 0.074 13.7 0.4 0.21 12.3 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 WW_FCH_linker PF16623.5 EAX76842.1 - 0.016 15.9 24.3 7.3 7.4 0.7 6.5 2 1 5 7 7 7 0 Unstructured linker region between on GAS7 protein KAAG1 PF15354.6 EAX76842.1 - 0.069 13.7 6.2 2.4 8.7 0.4 2.7 1 1 2 3 3 3 0 Kidney-associated antigen 1 BORG_CEP PF14957.6 EAX76842.1 - 4.4 8.5 22.9 3.3 8.9 5.8 4.0 2 1 1 3 3 3 0 Cdc42 effector DUF4106 PF13388.6 EAX76843.1 - 1.8e-242 804.9 17.2 1.8e-242 804.9 17.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX76843.1 - 0.027 14.3 0.2 0.067 13.0 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3452 PF11934.8 EAX76843.1 - 1.1 8.9 3.2 0.91 9.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) FapA PF03961.13 EAX76843.1 - 2.1 6.9 8.2 0.97 8.0 4.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EAX76843.1 - 6.9 6.6 5.7 1.8 8.5 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TFIIA PF03153.13 EAX76843.1 - 9 6.2 31.7 0.62 10.0 16.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FTCD_C PF04961.12 EAX76843.1 - 9.2 6.0 9.2 20 4.9 0.1 3.3 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase Pox_D5 PF03288.16 EAX76844.1 - 3.2e-05 24.3 2.4 0.0002 21.8 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX76845.1 - 8.7e-53 178.1 4.4 9.6e-53 178.0 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX76846.1 - 0.053 13.3 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3417 PF11897.8 EAX76846.1 - 0.077 13.5 0.4 0.085 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Pox_A32 PF04665.12 EAX76848.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76848.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76848.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76848.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX76849.1 - 1.1e-154 512.9 10.3 1.5e-154 512.5 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX76849.1 - 0.25 11.6 4.2 13 6.1 0.0 3.6 4 0 0 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX76850.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX76851.1 - 0.024 15.1 5.8 2.7 9.0 0.3 3.3 3 0 0 3 3 3 0 TMP repeat SL4P PF17618.2 EAX76852.1 - 0.57 10.3 3.2 13 5.9 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX76853.1 - 1.4e-115 384.9 10.9 1.8e-115 384.5 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX76853.1 - 0.046 14.2 3.3 0.29 11.6 0.0 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX76856.1 - 3e-05 24.0 4.0 3.7e-05 23.7 0.3 3.1 2 1 0 2 2 2 1 Phage tail repeat like DUF445 PF04286.12 EAX76856.1 - 0.0089 15.9 6.9 0.016 15.0 6.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX76856.1 - 0.013 15.9 0.9 0.11 12.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4116 PF13475.6 EAX76856.1 - 0.031 14.0 0.1 0.13 12.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Transposase_24 PF03004.14 EAX76856.1 - 0.12 12.5 2.2 0.54 10.4 0.3 2.7 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) Pox_D5 PF03288.16 EAX76857.1 - 3.6e-05 24.2 3.7 0.00027 21.3 3.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76857.1 - 0.05 14.2 0.1 0.09 13.4 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX76857.1 - 0.056 13.4 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX76858.1 - 4.9e-56 188.6 6.2 5.5e-56 188.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX76860.1 - 9.3e-29 99.3 12.2 9.3e-29 99.3 12.2 3.5 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX76860.1 - 0.00098 18.8 0.6 0.14 11.9 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) Imm32 PF15566.6 EAX76860.1 - 0.36 10.7 3.0 5.2 6.9 0.3 2.9 1 1 1 2 2 2 0 Immunity protein 32 Phage_fiber PF03335.13 EAX76860.1 - 0.58 10.5 8.3 12 6.4 0.2 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat DUF4108 PF13390.6 EAX76861.1 - 2.2e-63 212.5 7.2 2.4e-63 212.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX76862.1 - 0.058 13.3 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76862.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX76864.1 - 1.8e-80 269.9 9.6 2.4e-80 269.5 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX76864.1 - 0.089 12.6 1.1 0.34 10.7 1.1 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX76865.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76865.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX76865.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76865.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX76866.1 - 4.8e-09 36.2 1.8 4.8e-09 36.2 1.8 5.2 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX76866.1 - 0.042 13.6 0.9 0.097 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX76866.1 - 0.66 10.5 13.0 6.4 7.4 4.0 3.5 2 1 0 2 2 2 0 YmaF family DUF4108 PF13390.6 EAX76867.1 - 6.5e-57 191.5 4.2 7.2e-57 191.3 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX76868.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX76869.1 - 2e-07 30.8 0.6 1.7e-06 27.7 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX76869.1 - 0.045 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX76869.1 - 0.049 13.3 0.1 3.8 7.1 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76869.1 - 0.064 13.1 0.2 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Thymidine kinase DUF1043 PF06295.12 EAX76871.1 - 0.093 12.7 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX76871.1 - 0.12 12.3 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PSP PF04046.16 EAX76873.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX76875.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76876.1 - 5.7e-41 138.9 0.7 1.1e-40 137.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76876.1 - 0.0079 16.8 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX76876.1 - 0.75 10.1 3.1 0.29 11.4 0.4 1.7 2 1 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Mito_fiss_reg PF05308.11 EAX76877.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX76877.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal rve PF00665.26 EAX76878.1 - 7.4e-13 48.7 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EAX76878.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Hydrolase_6 PF13344.6 EAX76878.1 - 0.089 12.9 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase KilA-N PF04383.13 EAX76879.1 - 3.9e-32 110.4 0.3 1e-31 109.1 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Cep57_MT_bd PF06657.13 EAX76879.1 - 0.19 12.2 5.0 0.91 10.0 0.9 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2897 PF11446.8 EAX76881.1 - 0.93 9.4 3.2 1.8 8.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76882.1 - 6.8e-60 201.1 8.6 7.6e-60 201.0 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX76883.1 - 7.3e-05 23.2 2.5 0.00045 20.6 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX76883.1 - 0.032 13.3 1.1 0.046 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) TMP PF05017.14 EAX76884.1 - 0.038 14.5 4.6 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76885.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX76886.1 - 2.6e-15 56.2 0.7 7.1e-15 54.8 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76886.1 - 0.021 15.4 0.0 0.048 14.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family PTR PF12789.7 EAX76888.1 - 3.7e-23 81.4 11.7 8.6e-23 80.2 5.0 5.0 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX76888.1 - 0.021 14.5 11.2 0.034 13.8 1.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) GPS2_interact PF15784.5 EAX76889.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX76889.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MGC-24 PF05283.11 EAX76890.1 - 7.9 6.9 6.5 11 6.4 6.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MULE PF10551.9 EAX76891.1 - 7.4e-14 51.9 0.1 1.5e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX76891.1 - 0.36 10.5 4.4 0.18 11.5 1.1 2.0 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX76891.1 - 0.52 10.6 5.6 1.1 9.5 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX76891.1 - 0.91 9.3 5.3 1.5 8.6 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3035 PF11233.8 EAX76892.1 - 0.012 16.0 3.6 0.015 15.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF3781 PF12636.7 EAX76893.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4106 PF13388.6 EAX76894.1 - 1.5e-240 798.6 15.5 1.5e-240 798.6 15.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX76894.1 - 0.063 13.1 1.5 0.067 13.0 0.2 1.7 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) FapA PF03961.13 EAX76894.1 - 0.59 8.7 7.0 0.35 9.4 3.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EAX76894.1 - 4.1 7.4 5.2 1.9 8.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4108 PF13390.6 EAX76895.1 - 6.4e-48 162.3 2.8 7.4e-48 162.1 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX76895.1 - 0.092 13.0 0.1 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide AAA_22 PF13401.6 EAX76897.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX76897.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76897.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76897.1 - 0.00089 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76897.1 - 0.0026 17.5 0.2 0.27 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX76897.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76897.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX76897.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX76897.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX76897.1 - 0.25 11.6 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) CH PF00307.31 EAX76898.1 - 0.11 12.7 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF3781 PF12636.7 EAX76899.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX76900.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX76900.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX76901.1 - 0.042 13.8 7.2 0.065 13.2 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX76901.1 - 1.9 8.9 5.7 2.8 8.4 5.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX76902.1 - 2e-25 89.6 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX76902.1 - 0.14 12.6 0.7 0.6 10.6 0.1 1.9 1 1 0 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX76903.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76903.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76903.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76903.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX76903.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX76903.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX76904.1 - 6.8e-05 22.5 3.7 7.6e-05 22.3 2.2 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX76904.1 - 0.0045 17.0 0.6 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX76904.1 - 0.0097 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Gly-zipper_Omp PF13488.6 EAX76907.1 - 0.0056 16.7 9.1 0.008 16.2 9.1 1.2 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX76907.1 - 0.23 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76907.1 - 0.89 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX76908.1 - 2.3e-64 215.6 6.5 2.5e-64 215.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX76909.1 - 1 9.3 2.8 2.1 8.3 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX76910.1 - 1.9e-05 24.7 0.1 2.6e-05 24.3 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76910.1 - 0.00033 20.5 0.0 0.00043 20.1 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76910.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX76910.1 - 0.0015 18.8 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76910.1 - 0.0052 17.1 0.0 0.007 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76910.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX76910.1 - 0.062 13.0 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX76910.1 - 0.069 12.7 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX76910.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX76910.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain GPS2_interact PF15784.5 EAX76911.1 - 0.033 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX76914.1 - 3.2e-32 110.7 0.4 7.7e-32 109.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Alba PF01918.21 EAX76915.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 0 Alba TPR_20 PF14561.6 EAX76915.1 - 0.023 15.0 0.7 0.24 11.8 0.2 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 EAX76915.1 - 0.061 13.1 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PG_binding_2 PF08823.11 EAX76915.1 - 0.22 11.9 1.3 0.25 11.7 0.2 1.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF2939 PF11159.8 EAX76916.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76916.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76916.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX76917.1 - 0.0098 15.9 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Gly-zipper_Omp PF13488.6 EAX76919.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX76919.1 - 0.077 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX76919.1 - 0.084 12.1 0.0 0.094 12.0 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX76919.1 - 0.23 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX76919.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4106 PF13388.6 EAX76922.1 - 1.5e-240 798.6 35.8 3.3e-152 507.6 11.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76922.1 - 0.018 15.3 0.1 0.79 10.1 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated WYL_3 PF18488.1 EAX76922.1 - 0.92 9.9 6.6 9.1 6.7 0.4 3.2 3 0 0 3 3 3 0 WYL domain PapD_N PF00345.20 EAX76923.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX76924.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX76924.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX76924.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX76924.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX76925.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76925.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family CbtB PF09489.10 EAX76926.1 - 10 6.3 8.3 12 6.1 0.9 2.5 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Pox_A32 PF04665.12 EAX76928.1 - 1.3e-07 31.3 2.2 1.6e-07 31.1 2.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX76928.1 - 0.0029 17.3 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX76928.1 - 0.032 13.7 0.1 0.04 13.4 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX76928.1 - 0.046 13.4 0.1 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX76928.1 - 0.049 13.8 4.4 3.6 7.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF3783 PF12646.7 EAX76928.1 - 0.16 12.0 1.3 0.93 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX76929.1 - 5.3e-43 145.4 1.4 5.4e-43 145.4 0.1 1.7 2 1 1 3 3 3 1 KilA-N domain Parathyroid PF01279.17 EAX76929.1 - 0.0044 17.6 0.1 0.014 16.0 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX76929.1 - 1 9.4 4.5 5.7 7.0 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein KilA-N PF04383.13 EAX76930.1 - 2.1e-17 62.9 0.1 4.4e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX76930.1 - 0.072 12.5 0.5 0.14 11.5 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain TPR_MLP1_2 PF07926.12 EAX76931.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX76931.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX76931.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX76932.1 - 3.9e-07 29.8 2.3 7.5e-07 28.9 2.3 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX76932.1 - 0.0014 18.4 0.3 0.44 10.3 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX76932.1 - 0.0024 18.2 0.2 0.017 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX76932.1 - 0.0069 16.0 1.5 0.013 15.1 0.1 2.0 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX76932.1 - 0.047 13.5 1.1 0.085 12.6 0.7 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX76932.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase TPK_catalytic PF04263.16 EAX76932.1 - 0.08 13.0 0.7 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain ResIII PF04851.15 EAX76932.1 - 0.28 11.2 6.6 0.33 10.9 5.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1827 PF08860.10 EAX76932.1 - 0.3 11.3 3.5 9.5 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX76932.1 - 0.71 10.6 11.7 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF4107 PF13389.6 EAX76933.1 - 5e-49 166.6 14.3 2.9e-47 160.9 14.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76933.1 - 0.076 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX76934.1 - 4.3e-22 78.1 0.2 8.1e-22 77.2 0.2 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX76934.1 - 0.063 13.3 0.8 0.27 11.2 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Gly_rich PF12810.7 EAX76937.1 - 6.4e-11 42.6 2.3 7.7e-11 42.4 2.3 1.0 1 0 0 1 1 1 1 Glycine rich protein KilA-N PF04383.13 EAX76939.1 - 1.6e-34 118.1 0.1 3.9e-34 116.9 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX76939.1 - 0.0025 18.0 0.1 0.0065 16.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX76939.1 - 0.084 13.3 5.3 0.48 10.9 0.9 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 JMY PF15871.5 EAX76940.1 - 0.057 12.7 0.3 0.088 12.1 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Pox_D5 PF03288.16 EAX76941.1 - 0.00011 22.7 2.6 0.00073 20.0 2.6 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX76942.1 - 9.4e-61 203.9 7.4 1e-60 203.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX76944.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX76944.1 - 7.8e-05 22.7 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX76944.1 - 0.0001 22.1 0.4 0.35 10.6 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX76944.1 - 0.0004 20.2 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX76944.1 - 0.0011 18.8 1.0 0.0043 16.9 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76944.1 - 0.0087 16.4 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX76944.1 - 0.055 12.9 0.1 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX76944.1 - 0.07 13.6 0.1 0.42 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX76944.1 - 0.078 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX76944.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX76944.1 - 0.24 11.7 4.9 4.7 7.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) ResIII PF04851.15 EAX76945.1 - 3.7e-05 23.8 1.9 7.1e-05 22.9 1.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX76945.1 - 0.00032 20.5 0.0 0.00046 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX76945.1 - 0.00039 20.7 0.0 0.00069 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX76945.1 - 0.00066 19.6 0.9 0.0019 18.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX76945.1 - 0.0067 16.8 0.0 0.0091 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX76945.1 - 0.032 14.0 0.2 0.18 11.6 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX76945.1 - 0.042 13.3 0.1 0.098 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX76945.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX76945.1 - 0.15 12.3 4.2 4.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX76945.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX76945.1 - 0.76 10.2 4.3 0.31 11.5 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX76947.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX76948.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX76949.1 - 9.2e-59 197.5 8.5 1e-58 197.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX76950.1 - 5e-05 23.7 2.2 0.00031 21.2 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX76950.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX76951.1 - 1.6e-101 338.8 6.1 1.9e-101 338.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX76952.1 - 1.5e-79 266.9 9.6 2e-79 266.5 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX76952.1 - 0.37 11.2 1.8 1.4 9.3 0.8 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain T5orf172 PF10544.9 EAX76953.1 - 3.8e-07 30.6 0.1 9.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX76953.1 - 0.059 12.9 0.3 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF4106 PF13388.6 EAX76954.1 - 3.1e-265 879.9 45.3 1.8e-148 495.2 21.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76954.1 - 0.00056 20.2 0.2 0.035 14.4 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated DUF3839 PF12943.7 EAX76955.1 - 5.5e-156 517.2 14.5 6.9e-156 516.8 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX76955.1 - 1 9.7 4.8 11 6.5 0.1 3.5 4 0 0 4 4 4 0 Tup N-terminal Amidase02_C PF12123.8 EAX76956.1 - 0.0024 17.5 0.0 0.0066 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX76956.1 - 0.19 11.6 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX76958.1 - 2.4e-154 511.8 12.8 2.9e-154 511.5 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX76958.1 - 0.15 12.6 3.1 1.3 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX76958.1 - 0.23 11.3 1.9 0.56 10.0 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX76958.1 - 0.35 11.2 2.7 1.1 9.6 0.0 2.9 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX76958.1 - 0.68 10.4 6.6 3.1 8.3 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX76959.1 - 6.9e-40 135.4 1.8 8.1e-40 135.2 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX76959.1 - 0.0089 16.6 0.3 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family T5orf172 PF10544.9 EAX76960.1 - 4.6e-07 30.3 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX76960.1 - 0.013 15.4 2.7 0.069 13.0 0.9 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAX76960.1 - 0.057 14.4 0.2 0.98 10.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain TMP PF05017.14 EAX76962.1 - 0.081 13.5 3.3 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX76963.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2939 PF11159.8 EAX76964.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76964.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX76965.1 - 0.079 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX76965.1 - 0.084 12.9 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) ATG101 PF07855.12 EAX76966.1 - 1.1e-12 48.2 0.1 1.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 DUF4108 PF13390.6 EAX76969.1 - 3.5e-61 205.3 7.8 3.9e-61 205.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FAS_N PF17828.1 EAX76970.1 - 0.018 15.1 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PET PF06297.14 EAX76970.1 - 0.045 14.1 0.5 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 PET Domain DUF2939 PF11159.8 EAX76971.1 - 0.016 15.6 0.6 0.019 15.4 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX76971.1 - 3.3 7.7 6.2 3.7 7.5 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX76972.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX76972.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_D5 PF03288.16 EAX76973.1 - 9.7e-05 22.8 2.1 0.00056 20.3 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX76973.1 - 0.04 13.0 1.1 0.055 12.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Amidase02_C PF12123.8 EAX76976.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX76978.1 - 2.6e-07 30.4 1.0 1.3e-06 28.1 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX76978.1 - 0.059 13.0 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76978.1 - 0.097 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase PTR PF12789.7 EAX76979.1 - 8.5e-30 102.6 11.5 8.5e-30 102.6 11.5 3.5 4 1 0 4 4 4 1 Phage tail repeat like Pox_A32 PF04665.12 EAX76980.1 - 3e-07 30.1 0.7 1.8e-06 27.6 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX76980.1 - 0.06 13.0 0.2 1.4 8.5 0.2 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX76980.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX76980.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3385 PF11865.8 EAX76982.1 - 0.0074 16.2 0.3 0.012 15.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) P66_CC PF16563.5 EAX76982.1 - 0.063 12.9 1.0 0.14 11.8 1.0 1.6 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Plasmodium_Vir PF05795.11 EAX76983.1 - 0.06 12.8 12.6 0.069 12.6 12.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 EAX76983.1 - 0.17 11.9 15.2 0.18 11.8 15.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LAP1C PF05609.12 EAX76983.1 - 0.2 10.7 15.2 0.22 10.6 15.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Bacteriocin_II PF01721.18 EAX76983.1 - 0.21 11.7 6.7 89 3.3 0.0 4.8 2 2 3 5 5 5 0 Class II bacteriocin HCO3_cotransp PF00955.21 EAX76983.1 - 0.22 10.3 5.3 0.26 10.1 5.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family Neurensin PF14927.6 EAX76983.1 - 0.34 10.6 2.6 1.4 8.6 2.6 2.1 1 1 0 1 1 1 0 Neurensin Band_3_cyto PF07565.13 EAX76983.1 - 0.62 9.8 11.6 0.87 9.3 11.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sec62 PF03839.16 EAX76983.1 - 0.84 9.1 12.9 1.1 8.7 12.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 EAX76983.1 - 0.94 8.2 17.0 1 8.0 17.0 1.1 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 EAX76983.1 - 2.7 6.9 18.3 3.2 6.6 18.3 1.0 1 0 0 1 1 1 0 Mitoguardin RFXA_RFXANK_bdg PF15289.6 EAX76983.1 - 2.7 8.3 24.7 6.7 7.1 11.1 2.1 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain RR_TM4-6 PF06459.12 EAX76983.1 - 4.1 7.2 17.1 5 6.9 17.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.13 EAX76983.1 - 4.1 5.6 15.2 5 5.4 15.2 1.0 1 0 0 1 1 1 0 Menin MDFI PF15316.6 EAX76983.1 - 7.6 6.6 18.8 11 6.1 18.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Peptidase_S64 PF08192.11 EAX76983.1 - 8.1 4.8 22.5 8.6 4.7 22.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4090 PF13319.6 EAX76986.1 - 0.00056 20.1 4.6 17 5.7 0.0 5.1 2 1 6 8 8 8 5 Protein of unknown function (DUF4090) Transketolase_C PF02780.20 EAX76986.1 - 0.0022 17.8 8.1 9 6.2 0.0 6.0 1 1 5 7 7 7 1 Transketolase, C-terminal domain DUF4106 PF13388.6 EAX76987.1 - 1.7e-278 923.6 21.9 2.1e-278 923.3 21.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX76987.1 - 0.00057 20.1 0.2 0.025 14.9 0.3 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated Viral_P18 PF04521.13 EAX76988.1 - 0.0086 15.9 0.1 4.7 7.0 0.0 2.2 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein DUF2897 PF11446.8 EAX76989.1 - 0.32 10.9 3.2 0.65 9.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX76990.1 - 8.6e-58 194.3 4.2 9.5e-58 194.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX76991.1 - 5.9e-06 26.7 0.5 8.5e-06 26.2 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX76991.1 - 0.039 14.6 0.1 0.052 14.2 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX76991.1 - 0.073 13.1 0.4 0.12 12.4 0.4 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX76992.1 - 5.4e-145 481.2 8.9 6.9e-145 480.8 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX76992.1 - 0.29 11.6 2.0 5.8 7.5 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Tup_N PF08581.10 EAX76992.1 - 1 9.7 5.0 12 6.2 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal PapD_N PF00345.20 EAX76996.1 - 0.032 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX76996.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX77001.1 - 1.7e-23 83.2 9.9 5.7e-23 81.5 9.9 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX77002.1 - 0.046 13.8 0.8 0.046 13.8 0.8 4.0 3 1 1 4 4 4 0 Phage tail repeat like TMP PF05017.14 EAX77004.1 - 0.053 14.1 5.2 9.1 7.5 0.2 3.3 3 1 1 4 4 4 0 TMP repeat DUF2897 PF11446.8 EAX77005.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX77006.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77006.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77006.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77006.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77006.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77006.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77006.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77006.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX77006.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77006.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77006.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX77006.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX77006.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX77007.1 - 1.9e-136 453.2 13.9 2.1e-136 453.0 13.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX77007.1 - 0.067 12.7 0.1 0.21 11.1 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX77007.1 - 0.25 11.8 3.2 1.3 9.6 0.9 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX77007.1 - 0.39 11.0 2.4 1.9 8.8 0.0 2.7 2 1 1 3 3 3 0 Rx N-terminal domain DUF5398 PF17376.2 EAX77007.1 - 3.8 8.2 5.8 4.5 8.0 0.1 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX77009.1 - 3.2e-38 131.5 3.8 4.6e-38 131.0 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX77009.1 - 0.083 13.3 0.5 0.49 10.9 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DNA_pol_B_2 PF03175.13 EAX77010.1 - 5.3e-09 35.5 1.9 1.2e-08 34.3 1.0 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX77010.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX77010.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Pox_A32 PF04665.12 EAX77012.1 - 2.8e-07 30.3 2.6 3.9e-07 29.8 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77012.1 - 0.0049 16.5 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77012.1 - 0.061 12.8 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77012.1 - 0.067 12.9 0.2 0.48 10.1 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77012.1 - 0.099 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77012.1 - 0.22 11.5 2.2 1.4 8.9 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77012.1 - 0.64 10.2 8.4 6.2 7.0 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX77014.1 - 0.00058 20.4 0.1 0.0012 19.4 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX77014.1 - 0.0051 16.4 0.6 0.11 12.1 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX77014.1 - 0.032 14.1 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX77015.1 - 5.5e-119 396.0 11.9 7e-119 395.7 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77015.1 - 0.022 15.2 2.6 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX77015.1 - 0.16 11.8 1.6 0.43 10.4 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX77015.1 - 0.34 11.3 3.4 0.71 10.2 0.1 2.9 3 1 1 4 4 4 0 PRD domain DDR PF08841.10 EAX77017.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX77020.1 - 7.4e-61 204.3 8.3 8.3e-61 204.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3035 PF11233.8 EAX77022.1 - 0.072 13.4 3.4 0.087 13.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF3839 PF12943.7 EAX77023.1 - 1.6e-78 263.5 11.1 2.1e-78 263.2 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX77024.1 - 0.00048 20.6 0.2 0.0011 19.4 0.2 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX77025.1 - 2e-157 521.9 14.9 2.5e-157 521.6 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77025.1 - 0.65 10.5 6.9 2.3 8.8 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX77027.1 - 1.2e-05 25.8 0.2 3.4e-05 24.3 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX77029.1 - 6.4e-55 185.0 6.6 7.1e-55 184.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77029.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3417 PF11897.8 EAX77030.1 - 0.11 13.0 0.5 0.13 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAX77031.1 - 2.5e-129 429.9 8.1 2.9e-129 429.7 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX77031.1 - 0.059 12.9 1.0 0.082 12.4 0.6 1.5 1 1 0 1 1 1 0 Z1 domain NTP_transf_6 PF06042.11 EAX77031.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX77031.1 - 0.7 10.2 2.9 3.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Rx N-terminal domain ApbA_C PF08546.11 EAX77032.1 - 4.4e-27 94.8 0.1 7.5e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EAX77032.1 - 7e-22 77.7 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EAX77032.1 - 8.4e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EAX77032.1 - 0.00048 20.7 0.0 0.0014 19.2 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EAX77032.1 - 0.0022 18.2 0.0 0.0057 16.8 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EAX77032.1 - 0.012 15.5 0.3 0.042 13.7 0.0 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAX77032.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.2 1 1 0 1 1 1 0 TrkA-N domain DUF5603 PF18231.1 EAX77032.1 - 4.2 7.7 5.3 8.6 6.7 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5603) PapD_N PF00345.20 EAX77033.1 - 0.017 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX77033.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2897 PF11446.8 EAX77035.1 - 1.3 9.0 3.8 3.3 7.7 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77036.1 - 6.8e-60 201.1 6.5 7.6e-60 201.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77036.1 - 0.038 14.2 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX77037.1 - 1.1e-06 28.5 0.5 1.9e-06 27.7 0.1 1.6 2 1 0 2 2 2 1 KilA-N domain DUF4543 PF15076.6 EAX77037.1 - 0.012 15.7 0.3 0.026 14.6 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) EssA PF10661.9 EAX77037.1 - 4.4 7.2 8.8 11 5.8 8.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF4108 PF13390.6 EAX77039.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77039.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX77040.1 - 8.7e-05 22.9 2.2 0.00046 20.6 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77040.1 - 0.038 14.6 0.1 0.079 13.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77040.1 - 0.073 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX77041.1 - 2.8e-57 192.6 6.1 3.2e-57 192.5 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77042.1 - 0.15 11.9 2.1 0.32 10.9 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX77043.1 - 9.9e-10 37.9 3.4 7.2e-09 35.0 3.4 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX77043.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Amidase02_C PF12123.8 EAX77044.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX77045.1 - 2.4e-42 143.3 0.7 4.9e-42 142.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77045.1 - 0.024 15.3 0.1 0.059 14.0 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family ABC1 PF03109.16 EAX77045.1 - 0.044 13.9 0.6 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 ABC1 family T5orf172 PF10544.9 EAX77046.1 - 2.4e-06 28.0 0.2 5e-06 27.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_D5 PF03288.16 EAX77048.1 - 7.8e-05 23.1 2.9 0.00038 20.9 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77048.1 - 0.031 14.9 0.1 0.066 13.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77048.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX77049.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77050.1 - 0.036 14.0 3.0 0.066 13.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX77051.1 - 1.6e-10 40.8 0.0 4.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX77052.1 - 6.7e-100 333.5 4.5 7.6e-100 333.3 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX77052.1 - 0.056 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Zinc binding domain Gly-zipper_Omp PF13488.6 EAX77054.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX77054.1 - 0.18 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX77054.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77054.1 - 1.3 9.2 5.9 2.3 8.4 5.8 1.6 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PSP PF04046.16 EAX77055.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77056.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX77058.1 - 5.1e-71 238.1 3.5 7.7e-71 237.5 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX77058.1 - 0.02 15.2 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX77059.1 - 0.0032 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase HAUS-augmin3 PF14932.6 EAX77061.1 - 0.26 10.8 6.1 0.026 14.1 1.7 1.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3839 PF12943.7 EAX77062.1 - 2.8e-80 269.3 10.4 3.6e-80 268.9 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HSM3_C PF18794.1 EAX77063.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain TMP PF05017.14 EAX77065.1 - 0.36 11.6 3.5 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77066.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX77067.1 - 5.1e-63 209.0 42.1 6e-32 109.5 14.4 5.5 2 2 3 5 5 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX77067.1 - 0.03 14.0 1.0 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PTR PF12789.7 EAX77071.1 - 7e-62 205.4 47.6 5.3e-32 109.7 14.4 5.8 4 2 3 7 7 7 3 Phage tail repeat like Pox_A32 PF04665.12 EAX77075.1 - 1.4e-07 31.2 1.0 1.7e-07 31.0 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77075.1 - 0.041 13.5 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX77075.1 - 0.083 12.9 0.4 0.74 9.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX77075.1 - 0.093 12.5 0.1 0.23 11.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF1269 PF06897.12 EAX77076.1 - 0.51 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PTR PF12789.7 EAX77079.1 - 1.1e-12 47.9 33.7 1.4e-08 34.7 4.8 6.4 5 1 0 5 5 5 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX77079.1 - 0.001 19.3 0.2 6.3 7.0 0.1 3.4 1 1 1 3 3 3 1 Leukemia inhibitory factor receptor D2 domain Ribosomal_S4e PF00900.20 EAX77079.1 - 0.014 15.3 0.5 62 3.6 0.0 3.8 3 0 0 3 3 3 0 Ribosomal family S4e HCNGP PF07818.13 EAX77079.1 - 0.024 15.3 0.1 1.1e+02 3.5 0.0 3.8 3 0 0 3 3 3 0 HCNGP-like protein TT_ORF2a PF08197.11 EAX77079.1 - 0.036 14.1 0.0 50 4.0 0.0 3.3 3 0 0 3 3 3 0 pORF2a truncated protein IL2 PF00715.17 EAX77079.1 - 0.3 11.0 7.0 22 5.0 0.0 3.8 4 0 0 4 4 4 0 Interleukin 2 PTR PF12789.7 EAX77080.1 - 1e-166 541.2 123.2 3.4e-34 116.7 17.3 5.4 3 1 5 8 8 8 6 Phage tail repeat like Apolipoprotein PF01442.18 EAX77080.1 - 0.11 12.4 1.0 0.26 11.1 1.1 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2785 PF10978.8 EAX77080.1 - 0.22 11.3 7.9 2 8.1 5.9 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2785) AviRa PF11599.8 EAX77080.1 - 0.59 9.6 5.9 1.6 8.2 0.5 2.5 1 1 2 3 3 3 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX77080.1 - 2.2 8.7 12.4 43 4.5 0.1 5.7 1 1 6 7 7 7 0 TFIIH p62 subunit, N-terminal domain PapD_N PF00345.20 EAX77083.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX77083.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family JMY PF15871.5 EAX77084.1 - 0.05 12.9 0.3 0.085 12.1 0.3 1.4 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PRA-PH PF01503.17 EAX77085.1 - 0.29 11.6 3.0 4.1 7.9 4.2 2.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Gly-zipper_Omp PF13488.6 EAX77086.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX77086.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77086.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DNA_pol_B_2 PF03175.13 EAX77089.1 - 1.7e-28 99.8 6.3 3.1e-28 98.9 6.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX77089.1 - 0.057 12.7 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX77089.1 - 0.082 13.0 1.0 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) GPS2_interact PF15784.5 EAX77090.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX77090.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAM110_N PF14161.6 EAX77091.1 - 0.047 13.9 3.0 0.076 13.2 2.8 1.5 1 1 0 1 1 1 0 Centrosome-associated N terminus Trypan_PARP PF05887.11 EAX77091.1 - 0.1 12.6 5.9 0.16 12.0 5.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX77091.1 - 5.8 7.4 5.1 8.5 6.8 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1493 PF07377.12 EAX77092.1 - 0.082 13.4 0.8 0.17 12.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PapD_N PF00345.20 EAX77093.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX77093.1 - 0.081 12.9 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX77095.1 - 1.5e-07 31.1 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77095.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77095.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77095.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77095.1 - 0.084 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX77095.1 - 0.52 10.5 8.3 5.7 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX77096.1 - 5.9e-08 32.5 1.4 1e-07 31.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX77096.1 - 0.042 14.2 0.1 0.069 13.4 0.1 1.5 1 1 0 1 1 1 0 PRD domain DUF4108 PF13390.6 EAX77098.1 - 6.1e-62 207.8 8.5 6.8e-62 207.6 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX77100.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX77100.1 - 0.0027 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77100.1 - 0.0036 17.7 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77100.1 - 0.005 16.9 0.1 0.0066 16.5 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX77100.1 - 0.02 14.4 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX77100.1 - 0.047 13.3 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX77100.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX77100.1 - 0.11 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 EAX77100.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase PSP PF04046.16 EAX77102.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77103.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Pox_A32 PF04665.12 EAX77105.1 - 4.8e-08 32.8 1.5 5.9e-08 32.5 1.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77105.1 - 0.0036 17.0 0.1 0.0036 17.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX77105.1 - 0.022 14.8 0.8 0.048 13.7 0.7 1.6 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX77105.1 - 0.057 13.2 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77105.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77106.1 - 4.5e-135 448.7 15.0 5.5e-135 448.4 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX77106.1 - 0.24 11.9 2.2 5 7.7 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX77106.1 - 4.9 7.7 9.0 2.2 8.8 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX77107.1 - 4.8e-111 370.0 6.4 5.4e-111 369.8 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77108.1 - 1e-06 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX77109.1 - 0.00068 19.3 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77109.1 - 0.19 11.6 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PG_binding_2 PF08823.11 EAX77110.1 - 0.018 15.3 0.1 0.05 13.9 0.1 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Alba PF01918.21 EAX77110.1 - 0.039 13.8 0.1 0.085 12.7 0.1 1.7 1 1 0 1 1 1 0 Alba TPR_20 PF14561.6 EAX77110.1 - 0.047 14.0 0.6 0.59 10.5 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Y_phosphatase2 PF03162.13 EAX77111.1 - 0.0038 16.8 0.3 0.0069 16.0 0.3 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX77111.1 - 0.01 15.9 0.7 0.032 14.2 0.0 1.9 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX77111.1 - 0.02 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Thymosin PF01290.20 EAX77113.1 - 0.03 14.1 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Thymosin beta-4 family SVS_QK PF10578.9 EAX77113.1 - 0.089 13.4 0.9 14 6.6 0.1 2.6 2 0 0 2 2 2 0 Seminal vesicle protein repeat KilA-N PF04383.13 EAX77114.1 - 8e-25 86.9 0.3 2e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3837 PF12939.7 EAX77115.1 - 0.0015 18.9 3.7 6 7.3 0.1 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3837) DUF3924 PF13062.6 EAX77115.1 - 0.066 13.2 0.1 0.21 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) ITI_HC_C PF06668.12 EAX77115.1 - 0.64 9.6 7.1 0.19 11.3 3.2 1.9 2 0 0 2 2 2 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Herpes_VP19C PF03327.14 EAX77116.1 - 0.14 11.6 0.3 0.19 11.1 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Caskin-tail PF16632.5 EAX77116.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin TMP PF05017.14 EAX77117.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77118.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX77119.1 - 2.2e-152 508.1 21.5 1e-151 505.9 21.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX77119.1 - 0.058 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein CCDC53 PF10152.9 EAX77119.1 - 0.091 13.2 3.3 0.16 12.3 3.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SANTA PF09133.10 EAX77120.1 - 0.094 13.2 0.1 0.098 13.2 0.1 1.1 1 0 0 1 1 1 0 SANTA (SANT Associated) DUF4108 PF13390.6 EAX77122.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX77123.1 - 1e-06 28.4 3.0 1e-06 28.4 3.0 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX77123.1 - 4.1e-05 23.4 0.2 0.42 10.3 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX77123.1 - 4.5e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77123.1 - 0.00025 21.1 3.9 0.00042 20.4 2.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77123.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77123.1 - 0.0015 18.4 0.5 0.003 17.4 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77123.1 - 0.006 16.3 2.1 0.015 15.0 0.4 2.3 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77123.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX77123.1 - 0.092 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX77123.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX77123.1 - 0.12 12.8 0.4 0.92 9.9 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX77123.1 - 0.58 10.9 11.3 0.29 11.8 1.4 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX77123.1 - 0.64 10.3 4.5 9.7 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX77125.1 - 9.5e-67 224.2 3.1 1.3e-66 223.8 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) HD_3 PF13023.6 EAX77126.1 - 0.051 13.5 0.8 0.093 12.7 0.6 1.5 2 0 0 2 2 2 0 HD domain PapD_N PF00345.20 EAX77127.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX77130.1 - 1.7e-07 31.0 3.2 2.5e-07 30.4 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77130.1 - 0.0032 17.1 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77130.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77130.1 - 0.062 13.0 0.1 0.32 10.7 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77130.1 - 0.08 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX77130.1 - 0.41 10.9 8.5 5.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX77131.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX77133.1 - 1.8e-99 332.1 12.8 2.3e-99 331.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77133.1 - 0.036 13.9 1.1 0.14 12.0 1.1 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX77135.1 - 5.2e-07 29.4 4.1 7.2e-07 28.9 4.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77135.1 - 0.0039 16.9 0.2 0.0049 16.5 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77135.1 - 0.053 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77135.1 - 0.059 13.1 0.1 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX77135.1 - 0.38 11.0 8.7 4.4 7.5 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Adaptin_N PF01602.20 EAX77136.1 - 7.8e-22 77.5 0.0 7.9e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region YpsA PF06908.11 EAX77136.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Cnd1 PF12717.7 EAX77136.1 - 0.04 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF908 PF06012.12 EAX77136.1 - 0.072 12.5 0.2 0.1 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Vitellogenin_N PF01347.22 EAX77136.1 - 0.073 11.4 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region KilA-N PF04383.13 EAX77138.1 - 8.5e-16 57.8 0.5 2.5e-15 56.3 0.0 2.0 2 1 0 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX77138.1 - 0.00098 19.3 0.1 0.0023 18.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX77140.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77140.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77140.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77140.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77140.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77140.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77140.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX77141.1 - 4.9e-09 36.0 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX77141.1 - 0.16 11.4 0.3 0.32 10.4 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX77141.1 - 1.2 9.5 4.7 4.2 7.7 0.4 2.3 1 1 0 2 2 2 0 PRD domain EssA PF10661.9 EAX77141.1 - 3.5 7.5 7.8 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX77142.1 - 2.7e-154 511.6 11.6 3.2e-154 511.4 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77142.1 - 0.052 13.4 0.4 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX77142.1 - 0.39 11.0 2.2 1.8 8.9 0.0 2.7 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX77142.1 - 1.3 9.6 4.7 8 7.0 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX77144.1 - 8.1e-14 51.3 2.0 9.8e-13 47.8 2.0 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX77144.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX77144.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX77145.1 - 1e-86 290.4 6.6 1.1e-86 290.2 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX77146.1 - 2.7e-07 30.3 1.2 4.2e-07 29.7 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5365 PF17326.2 EAX77147.1 - 0.022 15.2 0.3 0.05 14.0 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) PTR PF12789.7 EAX77148.1 - 0.34 11.0 0.2 0.34 11.0 0.2 4.9 5 0 0 5 5 5 0 Phage tail repeat like Gp5_C PF06715.12 EAX77148.1 - 0.52 10.6 4.5 1.7 8.9 0.3 3.8 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) EMP24_GP25L PF01105.24 EAX77148.1 - 0.8 9.6 6.8 3.8 7.4 3.4 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD YmaF PF12788.7 EAX77148.1 - 1.9 9.1 9.4 1.1 9.8 0.3 3.3 2 2 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX77148.1 - 4.8 7.6 16.4 5.9 7.4 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX77149.1 - 0.03 14.8 0.5 0.067 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ResIII PF04851.15 EAX77150.1 - 4.8e-05 23.4 1.4 6.4e-05 23.0 0.4 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77150.1 - 0.0004 20.2 0.0 0.0006 19.6 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77150.1 - 0.0015 18.4 0.4 0.0041 17.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EAX77150.1 - 0.0022 18.3 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77150.1 - 0.0094 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TPK_catalytic PF04263.16 EAX77150.1 - 0.032 14.3 1.1 0.41 10.7 1.1 2.0 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX77150.1 - 0.047 13.1 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX77150.1 - 0.063 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF573 PF04504.14 EAX77150.1 - 0.066 13.9 4.7 0.064 13.9 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 AAA_25 PF13481.6 EAX77150.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX77150.1 - 0.22 11.2 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gly-zipper_Omp PF13488.6 EAX77151.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX77151.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77151.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX77152.1 - 1.3e-09 37.9 7.6 1.4e-08 34.7 4.8 4.8 5 1 1 6 6 6 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX77152.1 - 0.0069 16.3 4.9 2.1 8.3 1.6 3.6 1 1 2 3 3 3 1 emp24/gp25L/p24 family/GOLD LIFR_D2 PF17971.1 EAX77152.1 - 0.083 13.1 0.0 23 5.2 0.0 2.4 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain KinB_sensor PF16767.5 EAX77152.1 - 0.15 12.6 0.7 6.2 7.3 0.3 2.4 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB EpuA PF11772.8 EAX77152.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta IL2 PF00715.17 EAX77152.1 - 0.62 10.0 4.2 10 6.0 0.1 3.0 2 1 0 3 3 3 0 Interleukin 2 NPV_P10 PF05531.12 EAX77152.1 - 9.4 6.8 6.5 61 4.2 2.3 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4107 PF13389.6 EAX77154.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX77155.1 - 2.9e-33 114.1 0.1 2.9e-33 114.1 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX77155.1 - 0.019 15.2 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX77155.1 - 0.26 9.8 0.1 0.37 9.3 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMP PF05017.14 EAX77158.1 - 0.42 11.4 2.9 42 5.5 0.2 3.0 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77159.1 - 0.035 14.6 0.2 0.075 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX77160.1 - 0.061 13.9 6.7 5.2 8.2 0.4 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77161.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX77162.1 - 2.7e-71 239.0 3.9 3.7e-71 238.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX77162.1 - 0.15 10.5 0.4 0.2 10.0 0.4 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX77163.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX77165.1 - 7.3e-76 254.8 8.6 9.5e-76 254.4 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77165.1 - 0.065 13.8 0.4 0.097 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX77165.1 - 0.078 12.5 0.8 0.39 10.2 0.0 2.3 2 1 1 3 3 3 0 SLOG cluster2 DUF3839 PF12943.7 EAX77169.1 - 3.7e-128 426.0 8.0 4.2e-128 425.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX77171.1 - 2.5e-25 89.3 4.3 3.8e-25 88.8 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX77171.1 - 0.092 11.9 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II RecO_C PF02565.15 EAX77171.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal EMP24_GP25L PF01105.24 EAX77173.1 - 0.052 13.5 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PapD_N PF00345.20 EAX77173.1 - 0.07 13.0 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4108 PF13390.6 EAX77174.1 - 1.1e-56 190.7 3.5 1.3e-56 190.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77174.1 - 0.098 12.9 0.0 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4107 PF13389.6 EAX77176.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX77177.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HTH_11 PF08279.12 EAX77178.1 - 0.033 14.1 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 HTH domain INSC_LBD PF16748.5 EAX77178.1 - 0.51 9.8 1.6 5.6 6.5 0.0 2.7 3 0 0 3 3 3 0 Inscuteable LGN-binding domain DUF5065 PF16723.5 EAX77178.1 - 0.66 10.0 2.8 0.8 9.8 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4108 PF13390.6 EAX77180.1 - 6e-64 214.3 6.9 6.6e-64 214.1 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX77181.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX77181.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX77181.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX77181.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1493 PF07377.12 EAX77183.1 - 0.014 15.8 0.4 0.028 14.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX77184.1 - 3.7e-159 527.5 12.7 4.7e-159 527.2 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX77184.1 - 0.39 11.1 3.7 13 6.2 0.0 3.6 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX77184.1 - 1.1 9.8 6.9 2 8.9 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HNH_3 PF13392.6 EAX77185.1 - 1.9e-07 30.7 0.1 3.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Mito_fiss_reg PF05308.11 EAX77187.1 - 0.026 14.6 1.8 0.028 14.5 1.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX77187.1 - 0.27 10.7 5.5 0.26 10.7 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PSP PF04046.16 EAX77188.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX77189.1 - 1.1e-06 29.0 0.1 2.8e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX77189.1 - 0.0061 16.4 1.0 0.043 13.7 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX77190.1 - 2.6e-16 59.5 0.3 2.6e-16 59.5 0.3 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77190.1 - 0.0026 18.3 0.0 0.0059 17.2 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family T5orf172 PF10544.9 EAX77191.1 - 1.9e-07 31.6 0.4 3.9e-07 30.6 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX77191.1 - 0.12 13.0 0.3 0.33 11.7 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 GPS2_interact PF15784.5 EAX77194.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX77194.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX77195.1 - 1.4e-25 90.1 11.0 4.3e-25 88.5 11.0 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX77195.1 - 0.011 15.7 0.1 1 9.4 0.0 3.2 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX77196.1 - 6.3e-157 520.2 14.7 8.1e-157 519.9 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77196.1 - 0.2 11.5 1.3 0.65 9.8 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX77196.1 - 1.3 9.5 8.0 2.5 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HAUS-augmin3 PF14932.6 EAX77197.1 - 0.026 14.1 1.0 0.037 13.6 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Trypan_PARP PF05887.11 EAX77200.1 - 0.031 14.3 12.6 0.032 14.2 12.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX77201.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3470 PF11953.8 EAX77202.1 - 0.075 13.0 2.4 3.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) DUF3839 PF12943.7 EAX77205.1 - 4.6e-78 262.0 10.9 5.8e-78 261.7 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77205.1 - 0.026 15.1 0.5 0.043 14.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX77205.1 - 0.059 13.7 1.1 0.23 11.8 0.0 2.4 2 1 1 3 3 3 0 PRD domain LD_cluster2 PF18163.1 EAX77205.1 - 0.1 12.1 0.3 0.77 9.2 0.0 2.3 2 1 0 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX77206.1 - 1e-98 329.6 11.3 3.6e-98 327.8 11.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77206.1 - 0.01 16.3 3.0 1.7 9.2 0.0 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.12 EAX77206.1 - 0.069 13.6 0.8 0.16 12.5 0.8 1.7 1 1 0 1 1 1 0 Cell division protein ZapB TLE_N PF03920.15 EAX77206.1 - 0.09 12.9 0.9 0.26 11.4 0.6 2.0 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DNA_pol3_a_NII PF11490.8 EAX77206.1 - 2.1 8.2 8.7 3.2 7.7 3.1 2.4 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II PTR PF12789.7 EAX77208.1 - 5.3e-39 132.1 25.6 1.1e-21 76.7 7.7 4.9 4 2 1 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX77208.1 - 0.0047 16.6 8.3 0.34 10.5 6.6 2.9 2 1 1 3 3 3 3 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX77210.1 - 3.3e-39 134.8 5.0 4.6e-39 134.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX77210.1 - 0.15 12.5 1.2 1.1 9.7 1.1 2.3 2 1 0 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX77210.1 - 0.31 11.5 2.6 1.5 9.2 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain IKKbetaNEMObind PF12179.8 EAX77211.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Amidase02_C PF12123.8 EAX77212.1 - 0.0099 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX77213.1 - 2.9e-39 134.8 3.2 3.3e-39 134.6 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX77213.1 - 0.078 13.4 0.7 0.095 13.1 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX77214.1 - 3.9e-121 403.1 11.7 4.8e-121 402.8 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77214.1 - 0.019 15.4 2.9 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX77214.1 - 0.06 13.9 1.3 0.1 13.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX77215.1 - 8.3e-10 38.5 1.3 1.9e-09 37.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX77216.1 - 1.4e-16 60.3 1.9 1.4e-16 60.3 1.9 6.2 5 2 2 7 7 6 1 Phage tail repeat like DUF4795 PF16043.5 EAX77216.1 - 0.2 11.3 24.7 0.086 12.4 1.6 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX77217.1 - 1e-08 35.1 5.1 1e-08 35.1 5.1 3.4 4 0 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX77217.1 - 0.012 15.2 0.3 0.018 14.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) EpuA PF11772.8 EAX77217.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX77217.1 - 0.15 12.0 1.4 3 7.7 1.0 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Ank_2 PF12796.7 EAX77218.1 - 4.4e-25 88.1 5.9 3e-06 27.7 0.2 5.2 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX77218.1 - 8.2e-18 64.5 1.6 0.00067 20.2 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77218.1 - 5.8e-17 60.1 5.0 0.75 10.6 0.0 8.7 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.30 EAX77218.1 - 2.6e-15 56.1 1.8 0.16 12.5 0.0 7.6 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX77218.1 - 4.8e-11 42.7 3.6 0.098 13.0 0.0 6.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) GAT PF03127.14 EAX77218.1 - 0.06 13.7 0.1 0.56 10.6 0.0 2.3 2 0 0 2 2 2 0 GAT domain Pox_A32 PF04665.12 EAX77220.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77220.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77220.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77220.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77220.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77220.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77220.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77220.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX77220.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77220.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77220.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX77220.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Parathyroid PF01279.17 EAX77221.1 - 0.018 15.7 0.1 0.038 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Stanniocalcin PF03298.13 EAX77221.1 - 0.087 12.1 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Stanniocalcin family DDR PF08841.10 EAX77222.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX77224.1 - 2e-40 137.1 0.2 3.7e-40 136.2 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain LOH1CR12 PF10158.9 EAX77224.1 - 0.42 10.6 3.0 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX77226.1 - 1e-07 31.7 0.5 1.3e-07 31.4 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX77226.1 - 0.049 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77226.1 - 0.063 13.2 0.3 0.51 10.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Zot PF05707.12 EAX77226.1 - 0.068 12.8 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3839 PF12943.7 EAX77227.1 - 2.1e-121 403.9 13.3 2.7e-121 403.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77227.1 - 0.041 14.3 3.1 1.8 9.0 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX77227.1 - 0.11 12.0 0.8 0.31 10.5 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX77227.1 - 0.24 11.2 1.9 0.65 9.8 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX77227.1 - 0.32 11.6 1.9 0.29 11.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX77227.1 - 0.5 10.7 0.1 0.5 10.7 0.1 2.7 4 0 0 4 4 4 0 PRD domain KilA-N PF04383.13 EAX77229.1 - 2e-41 140.4 0.3 3.6e-41 139.5 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX77229.1 - 0.0074 16.9 0.2 0.02 15.5 0.0 1.7 2 1 0 2 2 2 1 Parathyroid hormone family Acyl_transf_2 PF02273.15 EAX77229.1 - 0.061 12.5 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase LOH1CR12 PF10158.9 EAX77229.1 - 0.65 10.0 3.9 1.8 8.6 0.3 2.2 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX77230.1 - 1.3e-06 28.9 0.2 3.7e-06 27.4 0.2 1.7 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX77230.1 - 0.029 14.2 0.1 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain Amidase02_C PF12123.8 EAX77234.1 - 0.0078 15.9 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX77235.1 - 1.2e-144 480.0 12.2 1.4e-144 479.8 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX77235.1 - 1 9.7 3.1 11 6.3 0.0 3.0 2 1 1 3 3 3 0 Rx N-terminal domain DUF2897 PF11446.8 EAX77236.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX77237.1 - 0.00056 19.5 1.9 0.00078 19.0 1.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Elong_Iki1 PF10483.9 EAX77237.1 - 0.03 13.8 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77237.1 - 0.032 14.0 0.3 0.22 11.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77237.1 - 0.047 13.5 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PTR PF12789.7 EAX77238.1 - 1e-51 172.8 37.3 1.4e-33 114.7 14.8 5.8 4 2 2 6 6 6 3 Phage tail repeat like DUF4116 PF13475.6 EAX77238.1 - 0.063 13.0 1.0 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) HNH_3 PF13392.6 EAX77239.1 - 1e-07 31.6 0.3 1.9e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3839 PF12943.7 EAX77241.1 - 1.4e-156 519.1 15.1 1.7e-156 518.8 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX77241.1 - 0.11 12.0 0.1 0.4 10.2 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX77241.1 - 0.97 9.9 7.8 2.3 8.8 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX77242.1 - 3.9e-07 29.8 1.4 6.8e-07 29.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MULE PF10551.9 EAX77243.1 - 4.9e-06 26.9 0.0 9.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF1878 PF08963.10 EAX77243.1 - 0.19 12.3 1.3 2.9 8.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) DUF2897 PF11446.8 EAX77244.1 - 0.044 13.7 3.0 0.079 12.9 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX77244.1 - 0.1 13.1 0.2 0.13 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX77245.1 - 4e-58 195.4 4.2 4.5e-58 195.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX77247.1 - 0.035 14.1 10.4 0.035 14.1 10.4 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX77247.1 - 0.53 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) HNH_3 PF13392.6 EAX77248.1 - 2e-07 30.6 0.1 3.4e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3839 PF12943.7 EAX77249.1 - 2.3e-80 269.6 10.4 2.9e-80 269.2 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BRE1 PF08647.11 EAX77249.1 - 0.46 10.6 2.9 2.1 8.5 1.2 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pox_A32 PF04665.12 EAX77250.1 - 5.7e-07 29.2 3.1 8.2e-07 28.7 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77250.1 - 0.0045 16.7 0.1 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77250.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77250.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77250.1 - 0.079 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77250.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77250.1 - 0.44 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX77251.1 - 2e-07 30.8 2.4 2.7e-07 30.3 1.6 1.8 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX77251.1 - 7.9e-05 22.5 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77251.1 - 9.6e-05 22.4 3.3 0.00022 21.3 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX77251.1 - 0.0012 18.5 0.4 0.0078 15.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EAX77251.1 - 0.0013 19.0 0.3 0.0093 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX77251.1 - 0.0027 17.5 0.1 0.005 16.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77251.1 - 0.0046 16.8 0.6 0.0092 15.8 0.6 1.7 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EAX77251.1 - 0.026 14.2 0.1 0.048 13.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF1827 PF08860.10 EAX77251.1 - 0.21 11.8 3.3 9.7 6.5 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX77253.1 - 2.8e-158 524.6 13.1 3.4e-158 524.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX77253.1 - 0.047 14.1 0.5 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX77253.1 - 2.8 8.4 7.3 4.3 7.9 0.3 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1199 PF06712.11 EAX77255.1 - 0.4 10.8 3.3 1 9.4 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1199) HTH_29 PF13551.6 EAX77256.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX77256.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DNA_pol_B_2 PF03175.13 EAX77257.1 - 2.8e-10 39.7 4.4 2.8e-10 39.7 4.4 2.3 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX77257.1 - 0.13 11.8 0.6 0.26 10.8 0.6 1.5 1 1 0 1 1 1 0 Isy1-like splicing family CompInhib_SCIN PF11546.8 EAX77258.1 - 0.018 15.1 0.7 0.02 14.9 0.7 1.1 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN FliD_N PF02465.18 EAX77260.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX77260.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YvrJ PF12841.7 EAX77261.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family PapD_N PF00345.20 EAX77262.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX77265.1 - 5.4e-09 36.0 10.5 1.4e-08 34.7 4.8 5.8 6 1 0 6 6 6 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX77265.1 - 0.0072 16.5 0.3 0.66 10.2 0.0 2.5 2 0 0 2 2 2 1 Leukemia inhibitory factor receptor D2 domain DUF1910 PF08928.10 EAX77265.1 - 0.029 14.4 0.5 4 7.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) IL2 PF00715.17 EAX77265.1 - 0.088 12.7 1.1 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Interleukin 2 Mito_fiss_reg PF05308.11 EAX77266.1 - 0.058 13.5 1.2 0.063 13.3 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX77266.1 - 0.63 9.5 5.8 0.66 9.4 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX77267.1 - 1.2e-96 322.9 7.6 1.4e-96 322.7 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX77267.1 - 0.11 13.5 0.6 3.3 8.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) DUF3839 PF12943.7 EAX77268.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX77268.1 - 0.067 13.3 0.1 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers Gly_rich PF12810.7 EAX77269.1 - 6.4e-19 68.8 41.1 7e-19 68.7 41.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Pox_A32 PF04665.12 EAX77270.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77270.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77270.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77270.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77270.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77270.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4106 PF13388.6 EAX77271.1 - 4.5e-274 909.0 38.8 3.7e-272 902.7 38.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77271.1 - 0.044 14.1 0.1 0.83 10.0 0.2 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated DIT1_PvcA PF05141.12 EAX77271.1 - 3.1 7.2 9.7 5.1 6.5 9.7 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF3839 PF12943.7 EAX77272.1 - 1.3e-102 342.4 8.6 1.5e-102 342.2 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX77273.1 - 5.1e-109 363.4 7.3 5.8e-109 363.2 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX77276.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77277.1 - 0.057 13.9 0.5 0.13 12.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX77278.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX77279.1 - 0.004 16.8 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX77282.1 - 3e-63 212.0 5.9 3.3e-63 211.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX77283.1 - 0.018 15.5 0.4 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX77283.1 - 1.6 8.8 4.8 1.7 8.7 4.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX77284.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX77285.1 - 3.1e-05 24.4 2.3 0.00019 21.9 2.3 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX77286.1 - 3.3e-148 491.7 9.5 4e-148 491.4 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77286.1 - 0.77 10.3 4.1 1.5 9.3 0.1 2.7 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ARA70 PF12489.8 EAX77288.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator KilA-N PF04383.13 EAX77289.1 - 6.5e-23 80.7 0.3 1.1e-22 80.0 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX77289.1 - 0.045 13.7 0.8 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX77291.1 - 6.9e-152 503.7 16.1 9e-152 503.4 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX77291.1 - 0.0041 16.5 1.9 0.0044 16.4 0.4 1.7 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) NTP_transf_6 PF06042.11 EAX77291.1 - 0.017 15.0 1.1 0.046 13.6 0.4 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX77291.1 - 0.031 14.7 0.8 0.53 10.7 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX77291.1 - 0.35 11.4 5.5 1.7 9.1 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase THOC7 PF05615.13 EAX77291.1 - 0.56 10.5 3.5 0.45 10.8 0.4 2.3 2 2 0 2 2 2 0 Tho complex subunit 7 DUF2408 PF10303.9 EAX77291.1 - 0.65 10.6 6.1 0.24 11.9 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX77291.1 - 3.3 8.1 6.9 1.4 9.3 0.1 3.4 4 1 1 5 5 5 0 PRD domain Pox_D5 PF03288.16 EAX77293.1 - 5.7e-05 23.5 3.6 0.00039 20.9 3.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77293.1 - 0.058 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77293.1 - 0.072 13.1 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX77294.1 - 1.5e-56 190.3 9.0 1.7e-56 190.1 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77295.1 - 1.4 8.8 4.9 3.1 7.8 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) UPF0175 PF03683.13 EAX77297.1 - 0.076 12.7 0.0 5.7 6.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) DUF4469 PF14734.6 EAX77298.1 - 0.079 13.1 0.1 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold DUF3839 PF12943.7 EAX77299.1 - 1.4e-133 443.7 8.3 1.7e-133 443.5 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX77299.1 - 0.04 14.1 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAX77299.1 - 0.24 12.0 1.9 0.57 10.8 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX77300.1 - 2.7e-16 59.4 0.2 5.3e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Armet PF10208.9 EAX77300.1 - 1.3 8.9 9.2 0.24 11.3 1.3 2.7 2 1 0 3 3 3 0 Degradation arginine-rich protein for mis-folding LRRCT PF01463.24 EAX77301.1 - 2.1e-06 27.8 6.8 1.6e+02 3.2 0.0 8.0 8 0 0 8 8 8 0 Leucine rich repeat C-terminal domain Zincin_1 PF06262.11 EAX77301.1 - 0.00019 21.5 1.3 3.3e+02 1.5 0.0 6.9 8 0 0 8 8 8 0 Zincin-like metallopeptidase CdiI_2 PF18593.1 EAX77301.1 - 0.00025 21.6 0.0 2.2e+02 2.6 0.0 5.4 6 0 0 6 6 6 0 CdiI immunity protein RFX_DNA_binding PF02257.15 EAX77302.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX77302.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX77302.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Flagellin_IN PF07196.13 EAX77303.1 - 0.19 11.9 3.5 0.53 10.5 3.3 1.9 1 1 0 1 1 1 0 Flagellin hook IN motif SapB_1 PF05184.15 EAX77303.1 - 4.7 7.3 5.8 4 7.5 0.2 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF3568 PF12092.8 EAX77303.1 - 7.7 6.6 7.8 0.45 10.6 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Pox_A32 PF04665.12 EAX77304.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77304.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77304.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77304.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77305.1 - 2.5e-79 266.2 9.6 3.3e-79 265.8 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77305.1 - 0.089 13.4 0.4 0.15 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX77305.1 - 0.12 12.7 1.3 0.51 10.7 0.1 2.5 2 1 0 3 3 3 0 PRD domain ZapB PF06005.12 EAX77305.1 - 0.28 11.7 1.4 1.1 9.7 0.2 2.3 3 0 0 3 3 3 0 Cell division protein ZapB DUF3839 PF12943.7 EAX77307.1 - 1.4e-104 348.8 7.9 1.6e-104 348.6 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_D5 PF03288.16 EAX77310.1 - 1.5e-05 25.4 1.0 2.2e-05 24.8 1.0 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77310.1 - 0.033 14.8 0.1 0.045 14.4 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77310.1 - 0.036 14.1 0.4 0.055 13.4 0.4 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX77311.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77311.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide CLIP_SPH_mas PF18398.1 EAX77313.1 - 0.065 13.7 0.7 4.5 7.8 0.4 2.3 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade KilA-N PF04383.13 EAX77314.1 - 2.5e-15 56.3 0.0 4.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain CPG4 PF15481.6 EAX77314.1 - 0.025 15.2 0.4 0.3 11.7 0.1 2.2 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 DUF3839 PF12943.7 EAX77315.1 - 4.8e-157 520.6 13.3 5.5e-157 520.4 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77315.1 - 1.2 9.7 7.4 1.5 9.3 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NMT PF01233.19 EAX77316.1 - 0.077 12.8 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Pox_A32 PF04665.12 EAX77317.1 - 8.5e-07 28.7 3.0 8.5e-07 28.7 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77317.1 - 3.3e-05 24.2 0.3 0.00023 21.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77317.1 - 7.9e-05 22.5 0.3 0.34 10.6 0.1 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77317.1 - 0.0002 21.4 3.8 0.00049 20.1 3.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77317.1 - 0.0007 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX77317.1 - 0.0017 18.1 0.6 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX77317.1 - 0.0025 17.7 1.1 0.0059 16.4 1.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77317.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX77317.1 - 0.065 12.8 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77317.1 - 0.073 13.5 0.1 0.6 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77317.1 - 0.094 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX77317.1 - 0.69 10.2 5.7 7.8 6.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX77317.1 - 1.1 9.8 4.7 0.55 10.7 1.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DDE_1 PF03184.19 EAX77318.1 - 2.6e-15 56.5 0.0 4.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4107 PF13389.6 EAX77320.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX77321.1 - 0.072 13.6 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4834 PF16118.5 EAX77322.1 - 5 8.2 5.9 6.6 7.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) GGDEF PF00990.21 EAX77323.1 - 0.093 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX77324.1 - 1.8e-61 206.3 8.3 2e-61 206.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX77325.1 - 6.7e-05 23.3 2.4 0.00036 20.9 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Mito_fiss_reg PF05308.11 EAX77326.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX77326.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Amidase02_C PF12123.8 EAX77327.1 - 0.0019 17.9 0.0 0.005 16.5 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77327.1 - 0.17 11.8 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX77329.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX77330.1 - 1.4e-118 394.7 11.8 1.7e-118 394.4 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77330.1 - 0.045 14.2 2.3 5.3 7.6 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX77330.1 - 0.19 11.6 2.0 0.48 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX77333.1 - 4e-23 81.2 14.3 4e-23 81.2 14.3 4.3 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX77333.1 - 0.056 13.2 0.9 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Macoilin PF09726.9 EAX77333.1 - 3.2 6.2 11.8 4.2 5.8 11.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF3781 PF12636.7 EAX77334.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX77335.1 - 0.059 13.8 1.8 0.079 13.4 1.8 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX77335.1 - 0.098 11.6 0.1 0.097 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX77336.1 - 0.042 13.8 7.8 0.065 13.2 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX77336.1 - 2.6 8.5 4.7 3.7 8.0 4.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX77338.1 - 2.7e-05 23.8 0.4 3.3e-05 23.5 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX77338.1 - 0.033 14.1 0.4 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX77339.1 - 1.3e-07 32.1 0.8 2e-06 28.3 0.3 2.3 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX77339.1 - 0.013 14.8 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 T5orf172 PF10544.9 EAX77340.1 - 2.5e-07 31.2 0.2 4.7e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX77341.1 - 2.2e-35 120.9 0.5 2.2e-35 120.9 0.5 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77341.1 - 0.0042 17.7 0.1 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family DUF2939 PF11159.8 EAX77342.1 - 0.017 15.6 0.7 0.021 15.2 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX77342.1 - 1.9 7.5 3.9 2 7.3 3.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX77342.1 - 3.9 7.5 7.3 4.4 7.3 7.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX77343.1 - 0.026 14.5 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Amidase02_C PF12123.8 EAX77344.1 - 0.0078 15.9 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase ABC2_membrane_3 PF12698.7 EAX77345.1 - 4.8e-05 22.6 1.2 6.1e-05 22.3 1.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4366 PF14283.6 EAX77345.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 EAX77345.1 - 0.0039 17.1 1.3 0.0053 16.7 1.3 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAX77345.1 - 0.0041 16.6 0.2 0.0046 16.4 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) BatD PF13584.6 EAX77345.1 - 0.0087 14.9 0.1 0.0094 14.8 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance RIFIN PF02009.16 EAX77345.1 - 0.013 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX77345.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX77345.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OppC_N PF12911.7 EAX77345.1 - 0.026 14.5 0.9 0.051 13.5 0.9 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FeoB_associated PF12669.7 EAX77345.1 - 0.037 14.4 2.1 0.061 13.7 2.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CD34_antigen PF06365.12 EAX77345.1 - 0.04 13.5 0.2 0.056 13.0 0.2 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 EAX77345.1 - 0.098 12.7 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gemini_mov PF01708.16 EAX77345.1 - 1.7 8.4 4.1 3.5 7.5 1.5 2.0 1 1 1 2 2 2 0 Geminivirus putative movement protein DUF257 PF03192.13 EAX77347.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX77347.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4108 PF13390.6 EAX77348.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PapD_N PF00345.20 EAX77351.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Ank_4 PF13637.6 EAX77352.1 - 2.2e-32 111.0 2.3 3.4e-10 40.3 0.1 4.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX77352.1 - 2.6e-29 101.6 0.4 5.2e-09 36.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX77352.1 - 1.6e-25 88.8 0.4 2.5e-07 30.8 0.1 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77352.1 - 6.4e-25 84.5 0.5 4.5e-05 23.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAX77352.1 - 6.5e-22 77.0 2.1 0.0002 21.7 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat DUF3447 PF11929.8 EAX77352.1 - 0.12 12.3 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DUF3839 PF12943.7 EAX77355.1 - 5.3e-93 310.9 6.9 6e-93 310.8 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RNase_3_N PF18497.1 EAX77358.1 - 0.00031 20.9 15.0 1 9.6 0.3 5.9 1 1 7 8 8 8 4 Ribonuclease III N-terminal domain Pep1_7 PF17232.2 EAX77358.1 - 0.07 13.6 22.7 65 4.1 0.0 7.6 1 1 7 8 8 8 0 Elicitor peptide 1-7 DHC_N1 PF08385.12 EAX77358.1 - 8.1 4.9 10.8 1.3 7.6 2.8 2.9 2 1 1 3 3 3 0 Dynein heavy chain, N-terminal region 1 DUF4108 PF13390.6 EAX77360.1 - 1.7e-61 206.3 8.9 1.9e-61 206.2 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Fumble PF03630.14 EAX77362.1 - 3e-50 171.3 1.5 3.6e-49 167.7 1.5 2.1 1 1 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 EAX77362.1 - 0.00051 19.6 0.3 0.0068 15.9 0.3 2.2 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 EAX77362.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family T5orf172 PF10544.9 EAX77363.1 - 0.00011 22.7 0.1 0.00025 21.5 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX77363.1 - 0.0056 16.2 0.4 0.033 13.7 0.1 1.9 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX77363.1 - 0.0079 16.0 0.1 0.022 14.6 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF4588 PF15251.6 EAX77364.1 - 0.022 14.5 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Ead_Ea22 PF13935.6 EAX77364.1 - 0.069 13.8 0.6 0.14 12.8 0.6 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Pox_A32 PF04665.12 EAX77365.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77365.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77365.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77365.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX77366.1 - 3.5e-56 187.1 32.9 1.7e-34 117.6 16.8 5.6 3 2 3 6 6 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX77366.1 - 0.079 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAX77369.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX77370.1 - 2.6e-29 102.5 7.1 4.5e-29 101.6 7.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX77370.1 - 0.022 14.1 0.2 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX77371.1 - 2.2e-157 521.7 13.8 2.8e-157 521.4 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX77371.1 - 0.037 14.3 0.9 11 6.4 0.0 3.5 3 0 0 3 3 3 0 Tup N-terminal Rx_N PF18052.1 EAX77371.1 - 0.064 13.5 0.6 5.8 7.2 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX77371.1 - 0.17 12.4 2.6 1.8 9.1 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX77371.1 - 1.4 9.5 5.2 0.46 11.0 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) FAS_N PF17828.1 EAX77372.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX77374.1 - 6.1e-140 464.6 12.0 6.7e-140 464.5 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77374.1 - 0.012 16.1 1.8 1.3 9.6 0.9 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MtrG PF04210.13 EAX77375.1 - 0.26 11.2 0.6 0.43 10.5 0.2 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3839 PF12943.7 EAX77376.1 - 1.5e-87 293.1 8.0 1.8e-87 292.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX77376.1 - 0.03 13.8 0.3 0.034 13.6 0.3 1.2 1 0 0 1 1 1 0 Z1 domain PTR PF12789.7 EAX77377.1 - 1.8e-18 66.3 29.3 2.8e-11 43.3 6.1 4.2 4 0 0 4 4 4 2 Phage tail repeat like EpuA PF11772.8 EAX77377.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta RraB PF06877.11 EAX77377.1 - 0.49 11.2 4.2 5.8 7.7 0.6 2.8 2 1 0 2 2 2 0 Regulator of ribonuclease activity B Phage_pRha PF09669.10 EAX77377.1 - 2.8 8.6 6.9 0.89 10.2 0.7 2.7 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Ras PF00071.22 EAX77378.1 - 9.5e-52 174.9 0.1 1.2e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX77378.1 - 7.8e-30 103.6 0.1 1.5e-29 102.7 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX77378.1 - 2.4e-18 66.2 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX77378.1 - 4.3e-09 36.1 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX77378.1 - 8.3e-06 25.3 0.0 9.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX77378.1 - 4.5e-05 23.1 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX77378.1 - 0.00012 22.1 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX77378.1 - 0.00032 20.7 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX77378.1 - 0.0018 18.5 0.1 0.012 15.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.20 EAX77378.1 - 0.016 14.4 0.0 0.082 12.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EAX77378.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAX77378.1 - 0.04 13.6 0.1 0.072 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAX77378.1 - 0.041 13.6 0.2 0.079 12.7 0.1 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain TniB PF05621.11 EAX77378.1 - 0.048 13.1 0.1 0.2 11.0 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 EAX77378.1 - 0.051 13.0 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EAX77378.1 - 0.053 12.9 0.1 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 EAX77378.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 EAX77378.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAX77378.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EAX77378.1 - 0.17 12.4 0.1 0.41 11.2 0.1 2.0 1 1 0 1 1 1 0 ABC transporter IKKbetaNEMObind PF12179.8 EAX77379.1 - 0.091 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain EF-hand_10 PF14788.6 EAX77380.1 - 0.0038 17.1 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 EF hand EVC2_like PF12297.8 EAX77380.1 - 0.0077 15.0 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein YABBY PF04690.13 EAX77380.1 - 0.016 15.8 0.6 0.039 14.5 0.6 1.5 1 0 0 1 1 1 0 YABBY protein 14-3-3 PF00244.20 EAX77380.1 - 0.028 13.9 2.7 2.8 7.4 1.4 2.5 2 0 0 2 2 2 0 14-3-3 protein KilA-N PF04383.13 EAX77382.1 - 8.6e-17 61.0 0.8 1.8e-16 60.0 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77382.1 - 0.01 16.4 0.1 0.026 15.2 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family ComA PF02679.15 EAX77385.1 - 0.069 12.6 0.9 0.08 12.4 0.9 1.0 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX77385.1 - 0.18 11.2 0.4 0.35 10.3 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX77386.1 - 1.5e-144 479.8 9.2 1.7e-144 479.5 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) AMP-binding_C_2 PF14535.6 EAX77386.1 - 0.038 14.3 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MitMem_reg PF13012.6 EAX77386.1 - 0.054 13.9 0.4 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function zf_CopZ PF18423.1 EAX77386.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 Zinc binding domain zf-C4pol PF14260.6 EAX77386.1 - 0.28 11.7 2.4 4.7 7.8 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Tup_N PF08581.10 EAX77386.1 - 0.64 10.4 5.2 3.5 8.0 0.3 3.1 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX77386.1 - 2.5 8.6 6.3 7.7 7.0 0.2 3.4 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CREPT PF16566.5 EAX77388.1 - 0.029 14.5 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX77388.1 - 0.93 9.7 6.0 0.33 11.1 1.6 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3839 PF12943.7 EAX77389.1 - 1.5e-78 263.6 10.2 2e-78 263.2 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77389.1 - 0.098 12.5 1.2 0.4 10.5 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX77391.1 - 5.3e-155 513.9 12.6 6.1e-155 513.7 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX77391.1 - 0.012 16.0 2.2 0.063 13.7 0.3 2.1 2 0 0 2 2 2 0 Fez1 DUF5398 PF17376.2 EAX77391.1 - 0.58 10.8 3.7 0.9 10.2 0.1 3.0 2 2 2 4 4 4 0 Family of unknown function (DUF5398) DUF2408 PF10303.9 EAX77391.1 - 1.3 9.6 5.5 0.98 10.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX77391.1 - 1.6 9.3 7.7 1.5 9.3 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX77393.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX77396.1 - 4.7e-147 487.9 12.6 5.5e-147 487.7 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77396.1 - 4.3 7.8 7.5 1.5 9.3 0.5 3.2 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX77397.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX77400.1 - 2e-15 56.5 16.6 9.9e-09 35.1 3.9 4.3 5 0 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX77400.1 - 1.1 8.8 14.4 11 5.6 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1690 PF07956.11 EAX77400.1 - 6.8 7.1 10.9 0.99 9.8 6.7 1.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Amidase02_C PF12123.8 EAX77401.1 - 0.006 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX77402.1 - 2.4e-48 164.3 0.5 3.4e-48 163.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX77402.1 - 0.093 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX77403.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77403.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77403.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77403.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MORN_2 PF07661.13 EAX77404.1 - 2.3e-06 27.2 0.2 42 4.8 0.0 5.9 6 0 0 6 6 6 2 MORN repeat variant SVS_QK PF10578.9 EAX77404.1 - 0.032 14.7 18.7 2.4 9.0 0.2 5.8 6 0 0 6 6 6 0 Seminal vesicle protein repeat Autophagy_N PF03986.13 EAX77404.1 - 0.038 13.9 1.4 3 7.8 0.0 3.5 2 2 2 4 4 4 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF4108 PF13390.6 EAX77405.1 - 4.9e-63 211.3 5.8 5.5e-63 211.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77406.1 - 0.063 13.2 2.3 0.087 12.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DDE_Tnp_ISL3 PF01610.17 EAX77409.1 - 8.2e-06 25.7 0.9 1.2e-05 25.2 0.9 1.2 1 0 0 1 1 1 1 Transposase T5orf172 PF10544.9 EAX77411.1 - 2.1e-05 25.0 0.3 5.4e-05 23.7 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Stanniocalcin PF03298.13 EAX77413.1 - 0.16 11.3 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Stanniocalcin family Pox_A32 PF04665.12 EAX77414.1 - 7.5e-07 28.8 2.4 7.5e-07 28.8 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX77414.1 - 3.1e-05 23.8 0.4 0.28 10.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX77414.1 - 5e-05 23.6 0.3 0.00036 20.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77414.1 - 0.00024 21.2 4.3 0.00046 20.2 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77414.1 - 0.00051 19.8 0.1 0.00094 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77414.1 - 0.002 18.0 1.2 0.0034 17.2 0.8 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77414.1 - 0.0057 16.3 2.8 0.014 15.1 0.4 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77414.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX77414.1 - 0.054 13.6 0.8 0.81 9.8 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX77414.1 - 0.094 12.3 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX77414.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX77414.1 - 0.11 12.9 0.1 1 9.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX77414.1 - 0.57 10.5 4.3 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX77414.1 - 1.1 9.9 11.9 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF3781 PF12636.7 EAX77416.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX77419.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77419.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77419.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77419.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77420.1 - 2.3e-81 272.9 10.8 2.9e-81 272.5 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77420.1 - 0.087 13.4 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX77420.1 - 0.15 11.9 1.2 0.45 10.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3781 PF12636.7 EAX77421.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX77422.1 - 3.9e-73 245.0 4.1 4.6e-73 244.7 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX77422.1 - 0.15 10.5 0.9 0.22 9.9 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase MtrG PF04210.13 EAX77423.1 - 0.032 14.1 0.2 0.06 13.2 0.0 1.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3837 PF12939.7 EAX77425.1 - 0.045 14.1 5.5 4.2 7.8 0.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF3837) DUF3924 PF13062.6 EAX77425.1 - 0.066 13.2 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) DUF4460 PF14687.6 EAX77425.1 - 9.9 6.3 10.5 0.49 10.5 0.4 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4460) DUF3781 PF12636.7 EAX77427.1 - 0.031 14.1 1.0 0.055 13.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) hEGF PF12661.7 EAX77428.1 - 2.9 8.6 5.1 7.9 7.3 5.1 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF DUF2939 PF11159.8 EAX77430.1 - 0.018 15.5 0.4 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX77430.1 - 1.5 7.8 2.9 1.6 7.7 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX77430.1 - 1.8 8.6 5.9 1.9 8.5 5.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX77431.1 - 0.017 15.1 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX77431.1 - 0.023 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal T5orf172 PF10544.9 EAX77432.1 - 2.2e-07 31.3 0.2 3e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX77432.1 - 0.023 14.2 0.3 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX77432.1 - 0.091 12.6 0.2 0.63 9.9 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain PSP PF04046.16 EAX77435.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX77436.1 - 5.4e-81 271.6 10.7 7.1e-81 271.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX77436.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX77436.1 - 0.25 11.2 1.8 0.97 9.3 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX77437.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77437.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77437.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77437.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77437.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77437.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77437.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX77438.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77438.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77438.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77438.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77439.1 - 2.2e-79 266.4 8.5 2.8e-79 266.0 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX77441.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77442.1 - 0.03 14.8 0.8 0.063 13.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX77443.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77443.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77443.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77443.1 - 0.063 13.0 0.2 0.33 10.6 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77443.1 - 0.073 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77443.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77443.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX77444.1 - 1.2e-25 90.4 3.8 1.7e-25 89.9 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX77445.1 - 4.8e-08 32.8 0.9 5.4e-08 32.6 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77445.1 - 0.0056 16.3 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX77445.1 - 0.027 14.5 0.7 0.059 13.4 0.6 1.7 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF3783 PF12646.7 EAX77445.1 - 0.06 13.3 0.4 0.55 10.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX77445.1 - 0.074 12.8 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Gly-zipper_Omp PF13488.6 EAX77448.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX77448.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77448.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif SHIRT PF18655.1 EAX77451.1 - 0.13 12.9 0.5 0.13 12.9 0.5 3.1 3 1 1 4 4 4 0 SHIRT domain SOBP PF15279.6 EAX77451.1 - 0.18 12.4 17.9 0.22 12.1 17.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 EAX77451.1 - 0.9 7.9 12.9 1.1 7.7 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Staufen_C PF16482.5 EAX77451.1 - 1 9.6 8.5 0.3 11.2 1.4 2.7 1 1 2 3 3 3 0 Staufen C-terminal domain PTR PF12789.7 EAX77453.1 - 1.7e-08 34.4 4.8 1.7e-08 34.4 4.8 6.2 5 1 0 5 5 5 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX77453.1 - 0.041 13.8 7.2 11 5.9 4.2 3.6 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Ribosomal_S4e PF00900.20 EAX77453.1 - 0.1 12.5 1.0 36 4.4 0.1 3.5 3 0 0 3 3 3 0 Ribosomal family S4e IL2 PF00715.17 EAX77453.1 - 0.36 10.7 3.8 9.3 6.2 0.1 2.9 3 0 0 3 3 3 0 Interleukin 2 DUF3839 PF12943.7 EAX77454.1 - 4.2e-151 501.2 16.8 5.1e-151 500.9 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX77454.1 - 0.064 13.7 2.9 0.13 12.7 0.5 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX77454.1 - 0.5 10.9 8.2 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX77454.1 - 6.9 7.0 8.1 11 6.4 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal Fumble PF03630.14 EAX77455.1 - 9.1e-43 146.7 0.3 1.1e-42 146.5 0.3 1.0 1 0 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 EAX77455.1 - 0.013 15.0 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 EAX77455.1 - 0.068 12.8 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Mid2 PF04478.12 EAX77456.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAX77456.1 - 0.00044 19.9 2.0 0.00071 19.3 2.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX77456.1 - 0.00053 20.1 0.0 0.00063 19.9 0.0 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EAX77456.1 - 0.0034 17.3 0.5 0.0055 16.6 0.3 1.4 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX77456.1 - 0.0035 17.2 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX77456.1 - 0.0043 17.3 0.8 0.0067 16.7 0.8 1.5 1 1 0 1 1 1 1 Glycophorin A ECSCR PF15820.5 EAX77456.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 EAX77456.1 - 0.022 15.1 0.2 0.029 14.6 0.2 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 EAX77456.1 - 0.034 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MtrF PF09472.10 EAX77456.1 - 0.04 13.3 3.5 0.068 12.6 3.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.6 EAX77456.1 - 0.05 14.5 0.1 0.11 13.4 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 EAX77456.1 - 0.056 12.5 0.1 0.09 11.8 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Gemini_mov PF01708.16 EAX77456.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein SKG6 PF08693.10 EAX77456.1 - 0.078 12.4 4.0 0.13 11.6 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 EAX77456.1 - 0.084 12.9 0.5 0.12 12.3 0.4 1.3 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5385 PF17359.2 EAX77456.1 - 0.085 12.4 1.0 0.86 9.1 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF2207 PF09972.9 EAX77456.1 - 0.094 11.5 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Otopetrin PF03189.13 EAX77456.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Cortexin PF11057.8 EAX77456.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney ODV-E18 PF10717.9 EAX77456.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 EAX77456.1 - 0.18 10.2 2.4 0.27 9.5 2.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Nucleopor_Nup85 PF07575.13 EAX77457.1 - 0.0033 16.1 0.0 0.0052 15.4 0.0 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin KilA-N PF04383.13 EAX77458.1 - 8.4e-36 122.2 1.0 1.5e-35 121.4 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77458.1 - 0.019 15.6 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX77459.1 - 1.3e-06 28.9 0.1 3.5e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX77459.1 - 0.0081 16.0 0.1 0.04 13.8 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain RNA_bind PF08675.11 EAX77459.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain FAS_N PF17828.1 EAX77461.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX77461.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF4108 PF13390.6 EAX77464.1 - 1.1e-62 210.2 7.3 1.2e-62 210.1 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX77465.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4106 PF13388.6 EAX77466.1 - 2.3e-278 923.1 22.1 3.4e-278 922.6 22.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77466.1 - 0.018 15.4 0.1 0.9 9.9 0.1 2.7 2 1 0 2 2 2 0 Kidney androgen-regulated VP4_2 PF08935.10 EAX77466.1 - 0.14 12.8 0.6 0.3 11.7 0.6 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX77466.1 - 1.9 8.9 7.7 10 6.6 0.4 3.4 3 0 0 3 3 3 0 WYL domain DUF3839 PF12943.7 EAX77467.1 - 1.7e-79 266.7 9.8 2.3e-79 266.2 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX77467.1 - 0.047 14.1 1.4 1.9 8.9 1.1 2.2 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF2408 PF10303.9 EAX77467.1 - 0.084 13.4 0.5 0.15 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX77467.1 - 0.1 12.9 1.1 0.19 12.0 0.3 1.9 3 0 0 3 3 3 0 PRD domain LD_cluster2 PF18163.1 EAX77467.1 - 0.14 11.7 0.1 0.83 9.1 0.0 2.1 2 1 1 3 3 3 0 SLOG cluster2 DUF3275 PF11679.8 EAX77470.1 - 0.021 14.8 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Mak16 PF04874.14 EAX77470.1 - 0.13 12.9 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region DUF3213 PF11491.8 EAX77471.1 - 0.028 14.6 0.5 0.065 13.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX77473.1 - 4.8e-81 271.8 10.0 6.2e-81 271.4 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) AAA_11 PF13086.6 EAX77476.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX77476.1 - 0.0053 17.0 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX77476.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.2 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 EAX77476.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EAX77476.1 - 0.016 15.2 0.1 0.019 14.9 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EAX77476.1 - 0.038 13.6 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX77476.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein PcfK PF14058.6 EAX77477.1 - 0.051 13.9 8.8 0.073 13.3 8.8 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX77477.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX77477.1 - 8.5 6.3 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX77478.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77478.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77478.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77478.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77478.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77478.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77478.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4107 PF13389.6 EAX77479.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PRP3 PF08572.10 EAX77481.1 - 0.023 14.4 2.0 0.026 14.3 2.0 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) PTR PF12789.7 EAX77481.1 - 0.041 13.9 1.0 0.07 13.2 0.2 1.9 2 0 0 2 2 2 0 Phage tail repeat like Med14 PF08638.11 EAX77483.1 - 0.095 12.1 0.1 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 Mediator complex subunit MED14 GPS2_interact PF15784.5 EAX77483.1 - 0.13 12.7 1.7 0.17 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX77487.1 - 4.7e-25 87.6 0.5 4.7e-25 87.6 0.5 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77487.1 - 0.0024 18.5 0.1 0.0077 16.8 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX77488.1 - 2.2e-07 30.6 0.7 1.3e-06 28.0 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX77488.1 - 0.051 13.7 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TK PF00265.18 EAX77488.1 - 0.058 13.3 0.2 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Zot PF05707.12 EAX77488.1 - 0.12 12.0 0.1 2.6 7.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Amidase02_C PF12123.8 EAX77489.1 - 0.0047 16.6 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77489.1 - 0.13 12.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX77490.1 - 1.9e-71 240.4 4.3 2.6e-71 239.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77490.1 - 0.072 13.7 0.3 0.099 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) AAA_22 PF13401.6 EAX77491.1 - 6.2e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77491.1 - 7.8e-05 22.7 3.2 0.00014 21.9 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77491.1 - 0.00038 20.3 0.0 0.00061 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77491.1 - 0.00088 19.1 0.9 0.0029 17.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77491.1 - 0.0072 16.7 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77491.1 - 0.0099 15.6 0.3 0.25 11.1 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX77491.1 - 0.044 13.2 0.1 0.068 12.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX77491.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX77491.1 - 0.1 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX77491.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX77491.1 - 0.18 12.1 4.7 3.9 7.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX77492.1 - 1.5 8.7 4.7 3.2 7.7 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77493.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX77495.1 - 0.72 9.4 2.4 0.56 9.8 0.8 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX77495.1 - 1.5 8.9 13.9 0.057 13.5 3.3 3.2 3 1 0 3 3 3 0 Phage tail repeat like AZUL PF16558.5 EAX77496.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PTR PF12789.7 EAX77497.1 - 7.1e-22 77.2 20.1 1.6e-16 60.1 1.3 5.0 5 1 1 6 6 6 2 Phage tail repeat like DUF3391 PF11871.8 EAX77497.1 - 0.11 13.0 0.3 0.76 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Plk4_PB1 PF18190.1 EAX77497.1 - 0.22 11.7 3.5 6.4 7.0 0.1 2.7 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 DUF4795 PF16043.5 EAX77497.1 - 1.5 8.4 20.8 0.099 12.2 6.0 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX77498.1 - 0.023 15.2 2.0 0.025 15.0 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX77499.1 - 3e-31 107.3 9.6 3e-31 107.3 9.6 2.5 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX77499.1 - 3.9 7.0 5.9 41 3.7 5.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAX77501.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77502.1 - 0.029 14.8 0.9 0.059 13.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Gly-zipper_Omp PF13488.6 EAX77503.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX77503.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77503.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2689 PF10894.8 EAX77505.1 - 0.011 15.4 3.8 2.7 7.9 0.1 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2689) MORN_2 PF07661.13 EAX77505.1 - 0.13 12.5 0.3 46 4.7 0.0 4.0 5 0 0 5 5 5 0 MORN repeat variant KilA-N PF04383.13 EAX77506.1 - 1.2e-30 105.7 0.5 2.7e-30 104.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77506.1 - 0.022 15.4 0.1 0.058 14.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX77507.1 - 5.3e-07 29.4 2.3 5.3e-07 29.4 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77507.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77507.1 - 5.4e-05 23.0 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77507.1 - 0.00022 21.2 4.2 0.00055 20.0 4.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77507.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77507.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77507.1 - 0.0018 18.0 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77507.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX77507.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77507.1 - 0.088 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77507.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3839 PF12943.7 EAX77508.1 - 1e-07 31.7 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX77509.1 - 7e-06 26.5 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain Csm1_N PF18504.1 EAX77511.1 - 0.0002 21.6 4.4 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX77511.1 - 0.00069 19.7 9.1 0.0033 17.5 9.2 1.8 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain HMMR_N PF15905.5 EAX77511.1 - 0.0019 17.7 4.1 0.0022 17.5 4.1 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 EAX77511.1 - 0.0028 18.0 3.7 0.0044 17.4 3.7 1.3 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX77511.1 - 0.0031 16.5 4.3 0.0036 16.2 4.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX77511.1 - 0.0054 16.5 5.5 0.0072 16.2 1.4 2.9 1 1 2 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX77511.1 - 0.0064 16.8 4.0 0.0095 16.3 4.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EAX77511.1 - 0.013 15.3 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EAX77511.1 - 0.013 15.6 6.1 0.016 15.3 6.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 EAX77511.1 - 0.018 14.4 4.0 0.022 14.0 4.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ADIP PF11559.8 EAX77511.1 - 0.028 14.5 7.4 0.043 13.9 7.2 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 EAX77511.1 - 0.038 13.4 5.1 0.045 13.1 5.1 1.1 1 0 0 1 1 1 0 FAM76 protein GNT-I PF03071.15 EAX77511.1 - 0.044 12.6 0.9 0.058 12.2 0.9 1.1 1 0 0 1 1 1 0 GNT-I family Atg14 PF10186.9 EAX77511.1 - 0.058 12.5 4.8 0.069 12.2 4.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EAX77511.1 - 0.094 12.9 9.9 0.12 12.6 9.9 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EAX77511.1 - 0.095 12.5 7.4 1.2 8.9 4.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 EAX77511.1 - 0.11 11.8 3.2 0.13 11.5 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 EAX77511.1 - 0.5 10.5 6.6 31 4.8 0.0 2.4 1 1 0 2 2 2 0 bZIP transcription factor COMP PF11598.8 EAX77511.1 - 0.97 10.0 5.8 2.3 8.7 3.1 2.2 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 EAX77511.1 - 2.2 8.1 8.5 2 8.2 3.6 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF3839 PF12943.7 EAX77513.1 - 2.8e-127 423.2 6.3 3.2e-127 423.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX77513.1 - 0.085 13.1 0.5 4.3 7.7 0.1 2.9 3 0 0 3 3 3 0 Rx N-terminal domain PTR PF12789.7 EAX77514.1 - 1.4e-73 242.8 50.6 9e-32 108.9 14.6 5.5 3 2 3 6 6 5 3 Phage tail repeat like AviRa PF11599.8 EAX77514.1 - 0.19 11.2 5.5 0.53 9.7 0.6 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa MULE PF10551.9 EAX77515.1 - 0.0069 16.8 2.1 0.053 13.9 0.1 2.8 2 1 1 3 3 3 1 MULE transposase domain DUF2960 PF11173.8 EAX77515.1 - 0.015 15.7 0.2 0.036 14.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Amidase02_C PF12123.8 EAX77517.1 - 0.0034 17.0 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX77518.1 - 0.0012 19.3 0.6 0.0022 18.5 0.2 1.6 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX77518.1 - 0.078 12.5 0.3 0.22 11.0 0.1 1.6 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX77519.1 - 7.8e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX77520.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77520.1 - 0.18 11.7 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) KilA-N PF04383.13 EAX77522.1 - 2.4e-43 146.5 0.1 3.2e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX77523.1 - 1.9e-65 220.7 5.0 2.5e-65 220.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX77523.1 - 0.014 15.9 0.3 0.017 15.6 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX77523.1 - 0.057 14.0 0.5 0.079 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) BRE1 PF08647.11 EAX77523.1 - 0.17 12.0 3.0 2.5 8.2 1.0 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4107 PF13389.6 EAX77524.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX77526.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Fungal_trans PF04082.18 EAX77528.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain FAS_N PF17828.1 EAX77532.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX77533.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX77534.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX77534.1 - 0.057 13.4 0.2 0.07 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX77535.1 - 4.8e-29 101.5 7.4 6.9e-29 101.0 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX77536.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77536.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77536.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77536.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) FAS_N PF17828.1 EAX77537.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX77538.1 - 0.019 15.4 0.4 0.026 14.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX77538.1 - 0.31 10.1 2.6 0.33 9.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX77538.1 - 1.5 8.9 5.5 1.6 8.8 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAX77539.1 - 0.03 14.3 0.5 0.041 13.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX77539.1 - 0.048 13.7 0.3 0.057 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pox_A32 PF04665.12 EAX77540.1 - 2.1e-07 30.6 2.1 3.2e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77540.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77540.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77540.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77540.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX77540.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX77540.1 - 0.55 10.4 8.3 5.8 7.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX77541.1 - 6e-07 30.0 0.2 1.1e-06 29.1 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX77542.1 - 1.7e-40 137.4 0.3 1.7e-40 137.4 0.3 1.8 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX77542.1 - 0.0047 17.1 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) JMY PF15871.5 EAX77543.1 - 0.012 14.9 0.5 0.021 14.1 0.5 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein 2_5_RNA_ligase2 PF13563.6 EAX77543.1 - 0.16 11.9 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily DUF5065 PF16723.5 EAX77543.1 - 1.3 9.1 4.0 0.69 10.0 0.9 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5065) TerB_N PF13208.6 EAX77544.1 - 0.0015 18.3 0.1 0.0017 18.1 0.1 1.0 1 0 0 1 1 1 1 TerB N-terminal domain PTR PF12789.7 EAX77545.1 - 4.5e-05 23.4 0.7 4.5e-05 23.4 0.7 4.0 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX77545.1 - 0.0071 16.2 6.1 0.01 15.7 6.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF2120 PF09893.9 EAX77545.1 - 0.045 13.8 3.1 0.22 11.7 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4116 PF13475.6 EAX77545.1 - 0.058 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX77545.1 - 0.13 11.9 0.4 3.2 7.4 0.3 2.4 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX77545.1 - 1 9.9 3.7 1.1 9.8 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX77545.1 - 6.6 6.3 17.6 2.3 7.7 8.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 EAX77546.1 - 9.2e-36 122.3 12.8 1.4e-14 54.4 0.5 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX77546.1 - 1.1e-28 98.9 6.0 9.7e-11 41.7 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX77546.1 - 3.7e-28 97.5 4.8 2.1e-11 44.1 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77546.1 - 9.8e-22 74.7 2.7 9.5e-07 28.7 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX77546.1 - 2.8e-20 71.8 6.4 3.7e-07 30.3 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat MetallophosN PF16371.5 EAX77546.1 - 0.0081 16.4 0.0 16 5.9 0.0 3.7 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase RGP PF03214.13 EAX77546.1 - 0.047 12.8 0.0 12 4.9 0.0 3.0 1 1 3 4 4 4 0 Reversibly glycosylated polypeptide S4 PF01479.25 EAX77546.1 - 0.078 12.7 0.0 33 4.3 0.0 3.3 4 0 0 4 4 4 0 S4 domain DUF348 PF03990.14 EAX77546.1 - 0.13 12.0 1.3 96 2.8 0.0 3.9 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain Stap_Strp_toxin PF01123.20 EAX77546.1 - 0.14 13.0 1.0 14 6.6 0.1 3.0 1 1 3 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3677 PF12432.8 EAX77546.1 - 0.17 12.2 0.0 32 4.9 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3677) PTR PF12789.7 EAX77547.1 - 1e-20 73.5 36.5 2.7e-11 43.3 5.8 5.2 5 0 0 5 5 5 3 Phage tail repeat like RraB PF06877.11 EAX77547.1 - 0.22 12.2 2.4 5.2 7.9 0.2 2.7 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Phage_pRha PF09669.10 EAX77547.1 - 1.3 9.6 5.4 1.1 9.9 0.7 2.7 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) DUF4355 PF14265.6 EAX77547.1 - 8 6.7 14.4 2.2 8.5 2.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) AAA_22 PF13401.6 EAX77548.1 - 3.4e-05 24.2 0.1 0.00021 21.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77548.1 - 6.5e-05 23.0 2.7 0.00011 22.3 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX77548.1 - 6.7e-05 22.7 0.3 0.29 10.9 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX77548.1 - 0.00043 20.1 0.0 0.0006 19.6 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77548.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77548.1 - 0.009 16.3 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX77548.1 - 0.059 12.8 0.0 0.09 12.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX77548.1 - 0.067 13.6 0.0 0.41 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX77548.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX77548.1 - 0.086 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX77548.1 - 0.19 12.0 4.1 6.2 7.1 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) HECT PF00632.25 EAX77550.1 - 1.6e-18 67.3 0.4 1.9e-18 67.0 0.4 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4108 PF13390.6 EAX77552.1 - 2e-57 193.1 4.5 2.2e-57 193.0 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX77554.1 - 1.2e-05 25.6 0.2 8.5e-05 22.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77554.1 - 5.2e-05 23.0 0.7 0.27 10.9 0.0 2.9 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77554.1 - 0.00011 22.2 4.1 0.00019 21.5 4.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77554.1 - 0.00036 20.3 0.1 0.00055 19.7 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77554.1 - 0.00057 19.8 1.2 0.0017 18.2 1.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77554.1 - 0.0057 17.0 0.0 0.0088 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX77554.1 - 0.046 14.1 0.1 0.77 10.2 0.0 2.2 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77554.1 - 0.05 13.1 0.1 0.09 12.2 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX77554.1 - 0.059 13.1 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX77554.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX77554.1 - 0.14 12.4 5.1 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX77554.1 - 2.1 8.8 5.2 0.73 10.3 1.3 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 PTR PF12789.7 EAX77555.1 - 1.6e-09 37.7 19.7 2.8e-08 33.7 5.2 3.7 4 0 0 4 4 4 2 Phage tail repeat like DUF4107 PF13389.6 EAX77558.1 - 4.5e-72 241.5 3.7 5.9e-72 241.1 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PadR PF03551.14 EAX77560.1 - 0.069 13.1 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DDE_1 PF03184.19 EAX77562.1 - 6.8e-09 35.6 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3839 PF12943.7 EAX77563.1 - 5.3e-76 255.3 10.1 7.1e-76 254.9 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77564.1 - 1.6e-45 153.5 0.1 3.3e-45 152.5 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX77564.1 - 0.0025 18.0 0.2 0.0068 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) DUF4108 PF13390.6 EAX77565.1 - 5.2e-63 211.2 7.1 5.8e-63 211.1 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX77567.1 - 1.1e-05 25.8 3.0 7.5e-05 23.1 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77567.1 - 0.0054 17.3 0.1 0.012 16.2 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77567.1 - 0.02 14.9 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF562 PF04763.12 EAX77567.1 - 0.023 14.1 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF562) DUF4108 PF13390.6 EAX77568.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX77569.1 - 6.9e-23 80.6 0.2 1.1e-22 80.0 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain MADF_DNA_bdg PF10545.9 EAX77569.1 - 0.052 13.9 0.2 0.099 13.0 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pox_A32 PF04665.12 EAX77570.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77570.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77570.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77570.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77570.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77570.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77570.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX77571.1 - 5.2e-31 108.0 13.3 2.5e-30 105.8 13.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX77571.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX77571.1 - 0.091 13.0 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) KilA-N PF04383.13 EAX77572.1 - 1e-41 141.2 0.1 1.5e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX77573.1 - 1.6e-128 427.2 4.9 1.8e-128 427.0 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX77574.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX77575.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77575.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77575.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77575.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77576.1 - 1e-79 267.5 9.0 1.3e-79 267.1 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX77577.1 - 1.4e-158 525.7 13.0 1.7e-158 525.4 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX77577.1 - 0.25 11.7 3.5 12 6.3 0.0 3.8 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX77577.1 - 1.8 9.1 7.0 2 8.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX77578.1 - 7.9e-60 202.3 3.8 8.8e-60 202.2 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77579.1 - 6.2e-11 42.1 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX77579.1 - 0.24 10.8 0.3 0.59 9.5 0.3 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX77579.1 - 0.82 9.5 7.2 1.8 8.4 7.2 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PapD_N PF00345.20 EAX77580.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX77580.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX77581.1 - 1.3e-12 47.5 25.4 1.3e-08 34.8 5.2 4.8 4 1 0 4 4 4 3 Phage tail repeat like Pox_A32 PF04665.12 EAX77582.1 - 1.2e-06 28.2 2.3 1.2e-06 28.2 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77582.1 - 3.9e-05 23.9 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77582.1 - 6.5e-05 22.7 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77582.1 - 0.00013 22.0 3.3 0.00032 20.7 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77582.1 - 0.00084 19.1 0.1 0.0016 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX77582.1 - 0.0015 18.2 0.5 0.013 15.2 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX77582.1 - 0.0026 17.6 1.1 0.0077 16.0 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77582.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77582.1 - 0.065 13.7 0.1 0.51 10.8 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX77582.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX77582.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX77582.1 - 0.17 12.3 3.4 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX77582.1 - 0.73 10.1 5.1 11 6.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX77582.1 - 1.7 9.1 5.0 0.59 10.6 1.1 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4107 PF13389.6 EAX77586.1 - 2.6e-73 245.5 4.3 3.1e-73 245.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX77586.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX77587.1 - 4.5e-95 317.7 6.7 7.4e-95 317.0 6.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX77587.1 - 0.013 15.0 0.3 0.015 14.8 0.3 1.1 1 0 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX77587.1 - 0.14 12.6 1.6 0.33 11.4 0.9 2.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX77588.1 - 5.6e-16 58.4 0.6 1.4e-15 57.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77588.1 - 0.027 15.1 0.0 0.062 13.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF4108 PF13390.6 EAX77591.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Lipid_DES PF08557.10 EAX77592.1 - 2 8.0 4.4 0.56 9.8 1.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) DUF4108 PF13390.6 EAX77596.1 - 2e-57 193.1 3.8 2.2e-57 193.0 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77596.1 - 0.095 12.9 0.1 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF1043 PF06295.12 EAX77597.1 - 0.055 13.5 0.3 0.07 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX77598.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX77598.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX77601.1 - 7.7e-57 191.2 5.9 8.5e-57 191.1 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX77603.1 - 3.3e-58 195.7 7.3 3.7e-58 195.5 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX77604.1 - 4e-45 152.3 1.5 4.4e-45 152.1 0.1 1.8 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX77604.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF4108 PF13390.6 EAX77605.1 - 6.4e-63 210.9 8.4 7.3e-63 210.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77607.1 - 0.13 12.1 2.2 0.18 11.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77608.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77608.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX77610.1 - 3.4e-118 393.4 7.5 3.9e-118 393.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77610.1 - 0.52 10.8 2.7 1.6 9.2 0.6 2.7 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UCH PF00443.29 EAX77611.1 - 0.0056 16.2 0.1 0.0056 16.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A32 PF04665.12 EAX77612.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77612.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77612.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77612.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77612.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77612.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77612.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX77613.1 - 4e-08 33.2 5.2 4e-08 33.2 5.2 4.0 5 0 0 5 5 5 2 Phage tail repeat like EpuA PF11772.8 EAX77613.1 - 0.15 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4795 PF16043.5 EAX77613.1 - 0.63 9.6 4.9 3.2 7.3 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) EMP24_GP25L PF01105.24 EAX77613.1 - 0.9 9.4 6.8 1.5 8.7 2.1 2.8 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Pox_A32 PF04665.12 EAX77614.1 - 1.4e-05 24.7 1.8 1.4e-05 24.7 1.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77614.1 - 2.5e-05 24.6 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77614.1 - 2.8e-05 23.9 0.3 0.39 10.4 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77614.1 - 0.00011 22.2 3.3 0.00024 21.1 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77614.1 - 0.00046 20.0 0.1 0.00087 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX77614.1 - 0.0016 18.1 0.5 0.011 15.3 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX77614.1 - 0.0016 18.2 0.9 0.0039 17.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77614.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX77614.1 - 0.056 13.0 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX77614.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX77614.1 - 0.069 13.6 0.1 0.6 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77614.1 - 0.076 12.5 0.1 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX77614.1 - 0.11 12.5 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX77614.1 - 0.24 11.6 5.0 3.8 7.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX77615.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX77616.1 - 2.4e-07 30.5 2.5 3.3e-07 30.0 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77616.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77616.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77616.1 - 0.059 13.1 0.3 0.25 11.0 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77616.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) TrmK PF04816.12 EAX77616.1 - 0.18 11.3 3.0 0.31 10.5 3.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DUF3783 PF12646.7 EAX77616.1 - 0.18 11.8 2.2 1.3 9.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77616.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4106 PF13388.6 EAX77617.1 - 3.7e-96 322.9 4.3 4.5e-96 322.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KilA-N PF04383.13 EAX77618.1 - 7.2e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX77618.1 - 0.038 14.0 0.5 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3781 PF12636.7 EAX77620.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) PTR PF12789.7 EAX77621.1 - 2e-09 37.3 9.5 2.1e-08 34.1 5.3 5.7 6 1 0 6 6 6 2 Phage tail repeat like Ribosomal_S4e PF00900.20 EAX77621.1 - 0.0036 17.2 0.4 3.9 7.5 0.0 3.0 2 0 0 2 2 2 2 Ribosomal family S4e PatG_C PF18065.1 EAX77621.1 - 0.0076 16.2 0.4 1.2 9.2 0.1 2.7 2 0 0 2 2 2 1 PatG C-terminal LIFR_D2 PF17971.1 EAX77621.1 - 0.035 14.3 0.1 11 6.3 0.1 2.6 1 1 2 3 3 3 0 Leukemia inhibitory factor receptor D2 domain KinB_sensor PF16767.5 EAX77621.1 - 0.55 10.7 2.5 17 5.9 0.3 3.1 2 1 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF2939 PF11159.8 EAX77623.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX77623.1 - 1.3 9.0 5.5 1.4 8.9 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX77624.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX77624.1 - 0.059 13.5 0.1 0.52 10.5 0.0 2.1 2 1 0 2 2 2 0 Associated with zinc fingers DUF3839 PF12943.7 EAX77625.1 - 8.3e-50 169.5 2.6 1e-49 169.2 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_4 PF13637.6 EAX77627.1 - 2.5e-22 79.0 0.5 2.8e-05 24.5 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX77627.1 - 8.6e-21 74.3 0.2 8.3e-09 35.9 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX77627.1 - 4.1e-13 48.2 0.0 0.49 11.1 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX77627.1 - 4.7e-13 49.1 0.0 0.00022 21.4 0.0 4.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX77627.1 - 1.5e-09 37.8 0.0 0.0012 19.2 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeat KilA-N PF04383.13 EAX77628.1 - 1.1e-28 99.3 0.5 2.7e-28 98.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77628.1 - 0.0042 17.7 0.0 0.013 16.1 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Med16 PF11635.8 EAX77629.1 - 0.013 13.4 0.0 0.013 13.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PTR PF12789.7 EAX77631.1 - 7.4e-35 118.8 28.2 1.9e-31 107.9 15.9 5.3 4 2 1 5 5 5 2 Phage tail repeat like PTR PF12789.7 EAX77632.1 - 2.4e-36 123.6 41.1 1.4e-33 114.8 15.3 5.1 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX77632.1 - 0.028 14.1 1.0 0.053 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX77632.1 - 0.75 10.4 14.5 4.3 7.9 14.4 2.3 1 1 0 1 1 1 0 YmaF family Amidase02_C PF12123.8 EAX77634.1 - 0.0068 16.1 0.1 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77634.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX77636.1 - 2.1e-159 528.3 13.6 2.7e-159 528.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77636.1 - 0.18 11.7 1.1 0.61 9.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX77636.1 - 0.53 10.8 5.2 2 8.9 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX77639.1 - 6.7e-80 268.0 9.5 8.6e-80 267.7 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4795 PF16043.5 EAX77640.1 - 0.0046 16.6 5.4 0.037 13.6 5.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX77640.1 - 1.8 8.9 6.3 7 7.1 0.7 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX77641.1 - 6.9e-155 513.6 13.5 8.6e-155 513.3 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX77641.1 - 0.11 12.0 0.5 0.65 9.5 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 KELK PF15796.5 EAX77641.1 - 1.4 9.5 6.8 4.3 7.9 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX77645.1 - 5e-59 196.2 39.3 2.1e-33 114.1 17.6 5.6 3 3 3 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX77645.1 - 0.021 14.6 0.1 0.089 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) ParD PF09386.10 EAX77645.1 - 0.11 12.9 8.2 9.6 6.7 0.9 4.1 1 1 3 4 4 4 0 Antitoxin ParD Imm32 PF15566.6 EAX77645.1 - 5.8 6.8 11.7 6.7 6.6 0.4 4.4 2 1 2 4 4 4 0 Immunity protein 32 DUF1493 PF07377.12 EAX77646.1 - 0.01 16.3 0.4 0.019 15.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Trypan_PARP PF05887.11 EAX77647.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) T5orf172 PF10544.9 EAX77648.1 - 1.1e-06 29.1 0.2 2.2e-06 28.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX77648.1 - 0.16 12.7 0.3 0.41 11.4 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4107 PF13389.6 EAX77649.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) La PF05383.17 EAX77650.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 La domain Ank_2 PF12796.7 EAX77651.1 - 2.7e-33 114.4 12.1 3.7e-20 72.3 3.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX77651.1 - 2.3e-31 106.8 7.2 4.6e-10 39.5 0.2 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX77651.1 - 2.1e-28 98.3 4.8 7.3e-10 39.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX77651.1 - 1.8e-24 85.5 8.1 9.6e-12 44.9 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77651.1 - 3.1e-24 82.4 2.8 1.1e-06 28.5 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ribosomal_S6 PF01250.17 EAX77651.1 - 0.035 14.4 0.1 0.74 10.1 0.0 2.4 1 1 2 3 3 3 0 Ribosomal protein S6 BRCT_2 PF16589.5 EAX77651.1 - 0.061 13.7 1.3 1.9 8.9 0.5 2.8 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain MTES_1575 PF18741.1 EAX77651.1 - 0.14 12.3 0.1 18 5.6 0.0 2.4 2 1 1 3 3 3 0 REase_MTES_1575 T5orf172 PF10544.9 EAX77654.1 - 4.9e-06 27.0 0.5 1.5e-05 25.5 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX77654.1 - 0.095 12.6 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX77655.1 - 2.5e-44 149.7 0.0 3.7e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX77656.1 - 2e-05 24.2 2.1 2e-05 24.2 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77656.1 - 2.5e-05 24.6 0.2 0.00018 21.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77656.1 - 3.8e-05 23.5 0.3 0.28 10.9 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77656.1 - 0.00014 21.9 3.5 0.00031 20.8 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77656.1 - 0.00047 20.0 0.1 0.00093 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX77656.1 - 0.0012 18.6 0.5 0.008 15.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX77656.1 - 0.0018 18.1 1.0 0.0049 16.7 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77656.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX77656.1 - 0.054 13.1 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX77656.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX77656.1 - 0.068 13.6 0.1 0.6 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77656.1 - 0.076 12.5 0.1 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX77656.1 - 0.32 11.3 4.6 6.7 7.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) RGS12_us1 PF16613.5 EAX77657.1 - 0.31 11.4 3.4 0.52 10.6 3.4 1.4 1 0 0 1 1 1 0 Unstructured region of RGS12 DASH_Dam1 PF08653.10 EAX77659.1 - 0.12 12.2 0.0 0.78 9.6 0.0 2.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 KilA-N PF04383.13 EAX77660.1 - 8.9e-34 115.7 0.0 1.2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX77661.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PapD_N PF00345.20 EAX77664.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX77665.1 - 2.9e-127 423.1 6.7 3.4e-127 422.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FAS_N PF17828.1 EAX77666.1 - 0.038 14.0 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX77667.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX77667.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX77668.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77668.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77668.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77668.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77668.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77668.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77668.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX77669.1 - 5.5e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX77669.1 - 0.035 14.2 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers PRD PF00874.20 EAX77669.1 - 0.046 14.0 0.4 0.14 12.5 0.1 2.0 1 1 1 2 2 2 0 PRD domain Mito_fiss_reg PF05308.11 EAX77671.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX77671.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX77672.1 - 1.7e-16 60.0 0.1 2.1e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX77672.1 - 0.072 13.1 0.5 0.079 12.9 0.5 1.0 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon T5orf172 PF10544.9 EAX77673.1 - 2.1e-05 25.0 0.4 6.8e-05 23.4 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX77673.1 - 0.021 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX77673.1 - 0.12 12.3 1.5 0.46 10.4 0.2 2.5 2 2 0 2 2 2 0 KilA-N domain DUF4108 PF13390.6 EAX77675.1 - 7.4e-61 204.3 7.6 8.3e-61 204.1 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX77676.1 - 2.7e-119 397.0 12.2 3.3e-119 396.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77676.1 - 0.011 16.1 2.2 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX77676.1 - 0.12 12.2 1.5 0.31 10.9 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX77676.1 - 0.74 10.2 0.1 0.74 10.2 0.1 2.8 4 0 0 4 4 4 0 PRD domain DUF5365 PF17326.2 EAX77677.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4108 PF13390.6 EAX77679.1 - 2.2e-43 147.6 3.1 2.3e-43 147.5 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX77681.1 - 0.1 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain TSGP1 PF07771.11 EAX77681.1 - 3.9 7.6 10.6 6.5 6.9 10.6 1.4 1 1 0 1 1 1 0 Tick salivary peptide group 1 DUF4108 PF13390.6 EAX77682.1 - 3.2e-63 211.9 7.0 3.5e-63 211.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX77683.1 - 1.9e-05 25.1 3.0 0.00015 22.2 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77683.1 - 0.084 13.5 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PadR PF03551.14 EAX77688.1 - 0.069 13.1 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX77691.1 - 3.1e-27 94.7 0.3 7.6e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77691.1 - 0.037 14.7 0.0 0.096 13.3 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF3040 PF11239.8 EAX77691.1 - 0.22 11.8 0.2 0.67 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ank_4 PF13637.6 EAX77693.1 - 2.2e-31 107.8 10.2 2e-09 37.8 0.3 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX77693.1 - 3.4e-26 91.7 7.3 1.5e-15 57.5 2.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX77693.1 - 5.6e-26 87.7 8.2 8.8e-06 25.7 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX77693.1 - 3.2e-24 84.7 9.1 3.6e-08 33.5 0.2 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX77693.1 - 2.3e-21 75.2 6.7 1.5e-07 31.5 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat DUF4107 PF13389.6 EAX77694.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX77695.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF3839 PF12943.7 EAX77696.1 - 1.2e-126 421.1 7.1 1.4e-126 420.9 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77696.1 - 0.11 13.0 1.3 1.2 9.6 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_11 PF13086.6 EAX77697.1 - 0.0013 18.6 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX77697.1 - 0.0032 17.8 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77697.1 - 0.0037 17.6 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX77697.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX77697.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX77697.1 - 0.043 13.4 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX77697.1 - 0.07 12.9 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX77697.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX77699.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX77700.1 - 2.9e-12 46.4 15.0 4e-12 46.0 7.2 4.3 5 0 0 5 5 5 2 Phage tail repeat like Cas_Csm6 PF09659.10 EAX77700.1 - 0.00023 20.0 4.2 0.017 13.9 2.1 2.2 1 1 1 2 2 2 2 CRISPR-associated protein (Cas_Csm6) Ribosomal_S4e PF00900.20 EAX77700.1 - 0.11 12.4 0.2 35 4.4 0.0 3.2 3 0 0 3 3 3 0 Ribosomal family S4e IL2 PF00715.17 EAX77700.1 - 0.18 11.7 2.1 13 5.7 0.1 2.6 2 1 0 2 2 2 0 Interleukin 2 KilA-N PF04383.13 EAX77701.1 - 3.4e-44 149.3 1.1 5.2e-44 148.7 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77701.1 - 0.019 15.6 0.1 0.067 13.8 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX77702.1 - 6.6e-08 32.3 0.9 7.8e-08 32.1 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77702.1 - 0.0038 16.9 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77702.1 - 0.043 13.5 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77702.1 - 0.065 13.2 0.4 0.59 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77704.1 - 1.5e-38 132.7 4.6 1.9e-38 132.3 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX77704.1 - 0.36 11.2 1.8 1.5 9.2 1.0 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX77705.1 - 9.4e-156 516.4 13.3 1.1e-155 516.2 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77705.1 - 0.32 11.5 4.6 0.85 10.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX77705.1 - 0.38 11.2 7.3 2.4 8.7 1.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX77705.1 - 0.74 10.1 4.7 2.9 8.2 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KilA-N PF04383.13 EAX77706.1 - 1.3e-16 60.5 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX77706.1 - 0.07 12.6 0.5 0.091 12.2 0.5 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX77706.1 - 0.28 10.6 0.5 0.58 9.5 0.5 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX77707.1 - 1.2e-108 362.2 6.7 1.4e-108 362.0 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX77708.1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX77708.1 - 0.17 11.8 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) FAS_N PF17828.1 EAX77709.1 - 0.018 15.0 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX77710.1 - 0.016 15.6 0.7 0.02 15.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX77710.1 - 2.3 7.1 4.9 2.3 7.2 4.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX77710.1 - 5 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FliJ PF02050.16 EAX77711.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3781 PF12636.7 EAX77712.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX77713.1 - 2.8e-11 43.3 0.2 5.8e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX77714.1 - 3e-07 30.1 3.0 4.5e-07 29.6 3.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77714.1 - 0.0059 16.3 0.1 0.0077 15.9 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77714.1 - 0.05 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77714.1 - 0.069 12.9 0.1 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77714.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77714.1 - 0.15 12.1 2.2 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX77714.1 - 0.15 12.4 2.3 0.22 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX77715.1 - 7.9e-25 87.7 4.5 1.2e-24 87.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX77715.1 - 0.054 13.8 1.0 0.19 12.1 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX77715.1 - 0.18 12.3 1.5 0.66 10.5 0.3 2.0 1 1 0 2 2 2 0 Cell division protein ZapB Pox_D5 PF03288.16 EAX77716.1 - 0.00026 21.4 2.2 0.0024 18.3 2.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77716.1 - 0.011 16.4 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77716.1 - 0.025 14.5 0.2 0.066 13.2 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF1697 PF08002.11 EAX77717.1 - 0.061 13.8 2.4 0.1 13.1 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1697) DUF3490 PF11995.8 EAX77717.1 - 0.084 12.7 1.5 0.12 12.2 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Amidase02_C PF12123.8 EAX77718.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX77719.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX77720.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX77721.1 - 0.045 14.2 0.5 0.058 13.8 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX77721.1 - 0.093 11.7 0.1 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX77722.1 - 0.021 14.8 7.9 0.033 14.2 7.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX77722.1 - 2 8.9 5.5 2.9 8.3 5.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4106 PF13388.6 EAX77725.1 - 1.2e-265 881.2 16.3 1.4e-265 881.0 16.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77725.1 - 0.016 15.5 0.1 0.65 10.3 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated Pox_A32 PF04665.12 EAX77726.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77726.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX77726.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX77726.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77726.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX77726.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF2294 PF10057.9 EAX77728.1 - 0.01 16.0 3.6 1.8 8.8 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF1935 PF09149.10 EAX77728.1 - 0.021 15.2 2.6 0.052 13.9 2.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1935) PS-DH PF14765.6 EAX77728.1 - 0.083 12.1 5.7 0.11 11.7 5.7 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase ETF PF01012.21 EAX77728.1 - 0.09 12.7 5.7 0.47 10.3 3.1 2.0 1 1 1 2 2 2 0 Electron transfer flavoprotein domain FAM219A PF15260.6 EAX77728.1 - 0.098 13.0 4.7 3.8 7.9 1.3 2.3 1 1 1 2 2 2 0 Protein family FAM219A Fucose_iso_C PF02952.17 EAX77728.1 - 0.13 11.9 0.8 0.39 10.4 0.2 1.8 1 1 1 2 2 2 0 L-fucose isomerase, C-terminal domain SPATA3 PF15662.5 EAX77728.1 - 0.33 11.6 8.4 0.42 11.2 8.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family MlaD PF02470.20 EAX77728.1 - 0.39 11.0 4.2 2.4 8.5 0.8 2.3 1 1 1 2 2 2 0 MlaD protein DUF3332 PF11810.8 EAX77728.1 - 0.69 9.5 5.2 0.97 9.0 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) RP-C_C PF11800.8 EAX77728.1 - 1.3 9.1 6.8 4 7.5 7.4 1.4 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF5077 PF16871.5 EAX77728.1 - 2 8.2 9.4 7.5 6.4 9.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) TP53IP5 PF15331.6 EAX77728.1 - 2.3 8.3 8.8 3 7.9 8.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MerB PF03243.15 EAX77728.1 - 6.6 6.9 10.3 8.5 6.5 3.4 2.2 1 1 1 2 2 2 0 Alkylmercury lyase DUF4106 PF13388.6 EAX77729.1 - 9e-258 855.3 20.2 1.2e-257 854.9 20.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77729.1 - 0.00072 19.8 0.2 0.035 14.4 0.3 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated Pox_D5 PF03288.16 EAX77730.1 - 2.1e-05 24.9 2.3 0.00011 22.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX77730.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX77731.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX77733.1 - 9.6e-151 500.0 13.5 1.2e-150 499.7 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77733.1 - 0.12 12.9 5.7 1.9 9.0 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX77733.1 - 2.5 8.5 6.5 8.5 6.8 0.1 3.7 4 2 0 4 4 4 0 Tup N-terminal Amidase02_C PF12123.8 EAX77735.1 - 0.0086 15.8 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DDE_1 PF03184.19 EAX77736.1 - 6.1e-16 58.6 0.1 9.2e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX77736.1 - 7.1e-05 22.6 0.0 0.0039 17.0 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PTR PF12789.7 EAX77738.1 - 1.1e-53 179.2 38.2 8e-35 118.7 16.3 4.0 4 1 1 5 5 5 3 Phage tail repeat like DUF3781 PF12636.7 EAX77740.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) PSP PF04046.16 EAX77741.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77742.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF563 PF04577.14 EAX77743.1 - 3.3e-11 43.7 0.1 6.3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MULE PF10551.9 EAX77743.1 - 1.7e-10 41.2 0.2 5e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX77743.1 - 0.045 12.6 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX77745.1 - 2.6e-155 514.9 13.7 3.3e-155 514.6 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX77745.1 - 1.1 9.6 3.4 1.2 9.5 0.6 2.5 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX77745.1 - 1.6 9.3 9.2 3.4 8.2 1.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX77746.1 - 2.5e-07 30.4 2.5 3.7e-07 29.9 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77746.1 - 0.0047 16.6 0.1 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77746.1 - 0.066 12.9 0.1 0.25 11.1 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77746.1 - 0.068 12.9 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77746.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX77748.1 - 6.1e-07 29.1 2.3 6.1e-07 29.1 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77748.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77748.1 - 4.3e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77748.1 - 0.00014 22.0 3.0 0.00032 20.7 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77748.1 - 0.00053 19.8 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77748.1 - 0.0015 18.4 0.8 0.0032 17.3 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77748.1 - 0.0019 17.9 0.4 0.014 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77748.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX77748.1 - 0.069 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX77748.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX77748.1 - 0.09 13.2 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77748.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX77748.1 - 0.42 10.9 4.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF5582 PF17819.1 EAX77749.1 - 0.095 13.2 4.6 0.11 12.9 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) POP1 PF06978.11 EAX77749.1 - 0.48 10.4 9.1 0.54 10.2 9.1 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 PA26 PF04636.13 EAX77749.1 - 4.1 6.2 7.5 4.5 6.1 7.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PapD_N PF00345.20 EAX77752.1 - 0.055 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX77752.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX77753.1 - 1.8e-154 512.2 12.9 2.1e-154 512.0 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77753.1 - 0.56 10.8 4.9 1 9.9 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX77753.1 - 1.7 9.2 6.3 4.4 7.8 0.2 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX77754.1 - 2.8e-06 27.8 0.2 6.5e-06 26.6 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Ank_4 PF13637.6 EAX77755.1 - 3.5e-09 37.0 0.3 4.5e-05 23.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX77755.1 - 2.8e-08 33.9 0.1 3.5e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX77755.1 - 4.7e-07 30.0 1.8 0.018 15.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX77755.1 - 4.3e-06 27.2 0.6 8.7e-06 26.2 0.4 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX77755.1 - 0.00027 21.1 0.9 0.016 15.7 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat DUF4108 PF13390.6 EAX77756.1 - 1.4e-39 135.3 1.1 1.6e-39 135.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX77756.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PG_binding_2 PF08823.11 EAX77758.1 - 0.027 14.8 0.1 0.079 13.3 0.1 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Alba PF01918.21 EAX77758.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Alba TPR_20 PF14561.6 EAX77758.1 - 0.11 12.9 0.5 1 9.8 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3839 PF12943.7 EAX77759.1 - 9.4e-08 31.8 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2400 PF09674.10 EAX77760.1 - 0.031 14.3 0.5 0.045 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX77760.1 - 0.032 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2362 PF10154.9 EAX77762.1 - 0.0014 17.7 3.8 0.002 17.2 3.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) PSP PF04046.16 EAX77764.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77765.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX77768.1 - 6e-08 32.4 1.4 1e-07 31.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX77769.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77769.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX77769.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX77769.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX77769.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX77769.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX77769.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX77770.1 - 1.4e-05 24.7 1.8 1.4e-05 24.7 1.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77770.1 - 2.5e-05 24.6 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77770.1 - 2.8e-05 23.9 0.3 0.39 10.4 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77770.1 - 0.00011 22.2 3.3 0.00024 21.1 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77770.1 - 0.00046 20.0 0.1 0.00087 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX77770.1 - 0.0016 18.1 0.5 0.011 15.3 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX77770.1 - 0.0016 18.2 0.9 0.0039 17.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77770.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX77770.1 - 0.056 13.0 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX77770.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX77770.1 - 0.069 13.6 0.1 0.6 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX77770.1 - 0.076 12.5 0.1 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX77770.1 - 0.11 12.5 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX77770.1 - 0.24 11.6 5.0 3.8 7.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX77772.1 - 0.035 14.6 0.6 0.076 13.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX77773.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX77773.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX77774.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX77774.1 - 0.075 12.0 0.1 0.07 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX77775.1 - 0.097 12.7 7.4 0.15 12.0 7.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX77776.1 - 5.7e-158 523.7 14.7 7.2e-158 523.3 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77776.1 - 3.2 8.3 7.3 2.5 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX77777.1 - 4.6e-59 198.5 6.7 5.1e-59 198.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77778.1 - 1.4 8.9 3.8 3.5 7.6 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX77779.1 - 3.7e-05 23.8 0.8 5.8e-05 23.2 0.5 1.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77779.1 - 0.00035 20.4 0.0 0.00054 19.8 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX77779.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX77779.1 - 0.0023 17.8 0.1 0.0042 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77779.1 - 0.0088 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77779.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 EAX77779.1 - 0.041 13.3 0.0 0.079 12.4 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX77779.1 - 0.068 13.2 0.6 0.61 10.1 0.6 2.0 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX77779.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF573 PF04504.14 EAX77779.1 - 1.2 9.8 8.1 0.1 13.3 1.7 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DNA_pol_B_2 PF03175.13 EAX77780.1 - 6e-09 35.3 1.0 1.2e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX77780.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX77780.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX77781.1 - 2.5e-19 69.2 0.3 3.4e-19 68.7 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX77782.1 - 1.7e-25 89.9 4.1 2.4e-25 89.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX77784.1 - 2.8e-09 36.4 0.8 5.4e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX77784.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX77785.1 - 6.6e-43 145.1 1.1 1e-42 144.5 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain ABC1 PF03109.16 EAX77785.1 - 0.018 15.2 1.2 0.31 11.2 0.1 2.6 1 1 1 2 2 2 0 ABC1 family Parathyroid PF01279.17 EAX77785.1 - 0.019 15.5 0.1 0.059 14.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX77786.1 - 6.2e-06 26.7 0.1 1.3e-05 25.7 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX77787.1 - 2.7e-81 272.6 11.0 3.5e-81 272.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77787.1 - 0.061 13.9 0.5 0.11 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Trypan_PARP PF05887.11 EAX77788.1 - 0.3 11.1 9.5 0.45 10.5 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX77790.1 - 3.8e-23 81.5 0.3 5.5e-23 81.0 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX77790.1 - 0.031 14.2 0.0 0.088 12.8 0.0 1.8 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Trypan_PARP PF05887.11 EAX77791.1 - 0.075 13.0 11.1 0.12 12.4 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX77793.1 - 1.9e-44 149.5 29.1 1.6e-30 104.9 12.3 5.6 4 1 2 6 6 6 3 Phage tail repeat like DUF2897 PF11446.8 EAX77794.1 - 8.1 6.4 6.5 17 5.4 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77795.1 - 3e-56 189.3 8.8 3.3e-56 189.2 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX77796.1 - 2.8e-152 505.0 10.2 3.2e-152 504.8 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77796.1 - 0.25 11.8 4.6 1.4 9.4 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX77797.1 - 5.3e-08 32.6 0.9 6.2e-08 32.4 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77797.1 - 0.0035 17.0 0.2 0.0037 16.9 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77797.1 - 0.061 13.1 0.1 0.14 11.8 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77797.1 - 0.082 12.9 0.3 0.71 9.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4107 PF13389.6 EAX77800.1 - 8.5e-53 178.8 9.4 5.4e-51 173.0 9.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX77802.1 - 5.3e-38 128.9 26.3 2.3e-32 110.8 13.8 4.7 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX77802.1 - 0.041 13.6 0.6 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX77802.1 - 1.8 9.1 6.1 13 6.4 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) PSP PF04046.16 EAX77804.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX77805.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX77807.1 - 1.4e-147 489.6 14.3 1.8e-147 489.3 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX77807.1 - 0.032 14.7 1.5 0.14 12.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX77807.1 - 0.21 12.0 6.3 2 8.9 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX77807.1 - 0.86 10.2 7.1 0.28 11.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) O-antigen_lig PF13425.6 EAX77808.1 - 1.6 7.4 3.5 2.1 7.0 3.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4108 PF13390.6 EAX77810.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77810.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX77811.1 - 1.6 8.7 4.7 3.2 7.7 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX77812.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX77813.1 - 2.3e-11 43.5 0.4 6.5e-11 42.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF4106 PF13388.6 EAX77814.1 - 1.2e-289 960.3 22.5 1.5e-289 960.0 22.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77814.1 - 0.029 14.7 0.1 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated Phage_fiber_2 PF03406.13 EAX77814.1 - 2.4 7.8 6.6 0.53 9.9 2.4 2.1 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX77816.1 - 6.3e-155 513.7 15.5 7.8e-155 513.4 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX77816.1 - 0.6 10.4 3.1 1 9.7 0.1 2.8 2 2 0 2 2 2 0 Rx N-terminal domain PapD_N PF00345.20 EAX77817.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX77817.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ARA70 PF12489.8 EAX77819.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Ribosomal_S21e PF01249.18 EAX77820.1 - 7.3e-34 115.7 0.0 8.3e-34 115.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pox_A32 PF04665.12 EAX77822.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77822.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77822.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77822.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PapD_N PF00345.20 EAX77823.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX77823.1 - 0.075 13.0 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PadR PF03551.14 EAX77823.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX77826.1 - 2.1e-23 83.0 3.9 2.4e-23 82.8 3.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX77827.1 - 7.9e-11 41.5 8.0 1.1e-10 41.1 4.2 2.0 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX77827.1 - 0.099 12.2 0.7 0.21 11.2 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX77827.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF3839 PF12943.7 EAX77828.1 - 1.8e-100 335.4 7.7 2.1e-100 335.2 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX77828.1 - 0.035 13.6 0.3 0.043 13.3 0.3 1.2 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX77828.1 - 0.61 10.7 3.0 2.3 8.9 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5398) PSP PF04046.16 EAX77829.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77830.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77831.1 - 0.044 14.2 0.4 0.13 12.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX77832.1 - 2.1e-154 512.0 13.2 2.5e-154 511.8 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77832.1 - 0.015 15.7 3.3 1.3 9.6 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX77832.1 - 0.42 11.2 5.2 0.43 11.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX77833.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77833.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77833.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77833.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX77834.1 - 1 9.3 3.6 2.4 8.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77835.1 - 4.4e-58 195.3 5.0 4.9e-58 195.1 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX77836.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX77836.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX77837.1 - 0.012 15.6 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX77838.1 - 2.3e-79 266.3 9.5 2.9e-79 265.9 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX77838.1 - 0.12 12.9 1.4 0.11 13.0 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX77838.1 - 0.17 12.4 0.3 1 9.8 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF1493 PF07377.12 EAX77839.1 - 0.022 15.2 0.2 0.029 14.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX77841.1 - 1.8e-56 190.1 6.3 1.9e-56 189.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX77842.1 - 0.00011 22.6 2.5 0.00051 20.5 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4107 PF13389.6 EAX77843.1 - 7.4e-53 179.0 9.8 4.7e-51 173.2 9.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX77844.1 - 8.5e-05 22.5 1.2 8.5e-05 22.5 1.2 2.8 3 0 0 3 3 3 1 Phage tail repeat like DEAD PF00270.29 EAX77845.1 - 2.9e-08 33.7 0.1 1.4e-07 31.4 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX77845.1 - 3.9e-06 27.0 2.6 6.4e-06 26.3 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DDE_1 PF03184.19 EAX77846.1 - 6.6e-16 58.5 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4107 PF13389.6 EAX77849.1 - 7.3e-73 244.1 3.0 9.5e-73 243.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX77851.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein TMP PF05017.14 EAX77853.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77854.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX77855.1 - 8.2e-104 346.3 7.8 9.5e-104 346.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX77855.1 - 0.19 12.2 1.3 0.81 10.2 1.3 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3781 PF12636.7 EAX77856.1 - 0.025 14.5 0.8 0.045 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Spo12 PF05032.12 EAX77857.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX77858.1 - 3e-154 511.5 13.4 3.7e-154 511.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX77858.1 - 0.77 10.3 3.5 0.79 10.3 1.4 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX77858.1 - 3.1 8.3 6.4 2 8.9 0.3 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX77859.1 - 2.8e-110 367.5 6.1 3.3e-110 367.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77860.1 - 9.7e-39 131.7 2.4 3.2e-37 126.8 2.4 2.6 1 1 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX77860.1 - 0.009 16.6 0.2 0.032 14.8 0.0 2.0 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX77861.1 - 2.7e-06 27.0 0.6 1.6e-05 24.5 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX77861.1 - 0.056 13.1 0.1 1.2 8.8 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) KilA-N PF04383.13 EAX77863.1 - 4e-23 81.4 0.3 5.9e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX77863.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TPR_MLP1_2 PF07926.12 EAX77864.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX77864.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX77864.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX77866.1 - 7.4e-155 513.5 12.8 9e-155 513.2 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77867.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX77867.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX77867.1 - 0.24 10.8 0.6 1.1 8.6 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Ank_4 PF13637.6 EAX77868.1 - 3.6e-26 91.2 3.7 2.2e-08 34.5 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX77868.1 - 3.8e-25 88.3 0.9 1e-10 42.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX77868.1 - 3.8e-23 81.2 0.3 7.1e-07 29.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77868.1 - 1.6e-19 67.9 0.3 4.1e-05 23.6 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX77868.1 - 2.2e-18 65.8 0.8 0.00018 21.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 EAX77868.1 - 0.0015 18.4 1.0 1.2 9.2 0.1 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) DUF3839 PF12943.7 EAX77869.1 - 1.4e-80 270.3 10.8 1.8e-80 269.9 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX77870.1 - 4.8e-41 139.1 1.4 7.5e-41 138.5 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DUF4108 PF13390.6 EAX77871.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DAO_C PF16901.5 EAX77872.1 - 0.1 12.5 0.1 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF2897 PF11446.8 EAX77872.1 - 1.2 9.0 4.2 1.6 8.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OAD_gamma PF04277.13 EAX77872.1 - 6.6 7.4 6.0 6.7 7.4 6.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ank_2 PF12796.7 EAX77873.1 - 2.4e-06 28.0 0.0 0.0077 16.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX77873.1 - 0.00069 20.1 0.0 1.1 9.9 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX77873.1 - 0.0012 19.1 0.0 1.3 9.8 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 EAX77873.1 - 0.0036 17.2 2.6 0.0036 17.2 2.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX77873.1 - 0.1 13.1 0.0 14 6.3 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat PSP PF04046.16 EAX77874.1 - 0.052 13.4 0.7 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX77875.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX77876.1 - 0.055 13.9 1.5 0.08 13.4 0.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF1031 PF06275.11 EAX77877.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DNA_pol_B_2 PF03175.13 EAX77879.1 - 3.8e-10 39.2 1.7 5.2e-10 38.8 1.0 1.5 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral DAGK_cat PF00781.24 EAX77881.1 - 1.2e-21 76.6 0.0 1.7e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 EAX77881.1 - 1.1e-05 25.8 0.1 2.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain Trypan_PARP PF05887.11 EAX77883.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX77883.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gly-zipper_Omp PF13488.6 EAX77885.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX77885.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX77885.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX77885.1 - 3 8.9 0.2 3 8.9 0.2 3.4 4 0 0 4 4 4 0 TMP repeat FadA PF09403.10 EAX77886.1 - 0.0071 16.8 2.1 0.011 16.2 0.4 2.1 2 0 0 2 2 2 1 Adhesion protein FadA Pox_A32 PF04665.12 EAX77887.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Nup35_RRM PF05172.13 EAX77888.1 - 0.055 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Trypan_PARP PF05887.11 EAX77889.1 - 0.031 14.3 8.5 0.041 13.9 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX77889.1 - 1.9 8.9 5.6 2.4 8.6 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin UCH PF00443.29 EAX77890.1 - 3.7e-28 98.7 1.8 4.3e-28 98.5 1.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX77890.1 - 6.5e-08 32.5 1.0 7.6e-08 32.3 1.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M8 PF01457.16 EAX77891.1 - 2.5e-08 33.1 0.0 2.9e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Pox_D5 PF03288.16 EAX77892.1 - 0.00019 21.9 3.1 0.001 19.5 3.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX77892.1 - 0.021 13.9 1.0 0.03 13.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX77892.1 - 0.056 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX77892.1 - 0.057 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX77893.1 - 1.9e-62 209.4 6.6 2.1e-62 209.3 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX77895.1 - 1.1e-113 378.6 7.8 1.3e-113 378.4 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX77895.1 - 0.15 13.0 0.7 4.6 8.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Mgr1 PF08602.10 EAX77896.1 - 2.2 7.0 10.2 2.3 7.0 10.2 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1129 PF06570.11 EAX77896.1 - 2.7 7.4 4.8 2.8 7.4 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ECH_1 PF00378.20 EAX77897.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF4107 PF13389.6 EAX77899.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ResIII PF04851.15 EAX77900.1 - 0.00012 22.2 4.3 0.00017 21.6 3.5 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX77900.1 - 0.00026 21.3 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX77900.1 - 0.00054 19.8 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77900.1 - 0.0014 18.4 0.8 0.0034 17.2 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77900.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX77900.1 - 0.027 14.2 0.2 0.17 11.6 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX77900.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX77900.1 - 0.12 12.5 0.5 1.1 9.3 0.5 2.2 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX77900.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF573 PF04504.14 EAX77900.1 - 0.91 10.2 9.5 0.14 12.8 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX77900.1 - 0.92 9.8 5.6 6.6 7.1 0.2 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX77902.1 - 9.9e-57 190.9 4.3 1.1e-56 190.7 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX77903.1 - 1.1e-06 29.1 0.1 2.8e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX77903.1 - 0.0046 16.8 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX77904.1 - 1.1e-29 103.6 6.5 2e-29 102.8 6.5 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX77904.1 - 0.018 14.4 0.2 0.028 13.7 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX77904.1 - 0.16 12.0 0.6 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4106 PF13388.6 EAX77907.1 - 2.4e-249 827.5 19.0 3.1e-249 827.2 19.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX77907.1 - 0.00074 19.8 0.6 0.03 14.6 0.3 2.7 3 0 0 3 3 3 1 Kidney androgen-regulated EpuA PF11772.8 EAX77908.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX77908.1 - 0.068 13.2 0.3 0.068 13.2 0.3 3.5 4 0 0 4 4 4 0 Phage tail repeat like Phage_fiber PF03335.13 EAX77908.1 - 5.9 7.3 20.9 5.3 7.5 0.5 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat PTR PF12789.7 EAX77909.1 - 1.9e-22 79.1 8.3 3.2e-16 59.1 2.0 6.1 7 1 1 8 8 8 2 Phage tail repeat like Peptidase_C78 PF07910.13 EAX77909.1 - 0.05 13.1 0.4 6 6.3 0.0 2.5 1 1 1 2 2 2 0 Peptidase family C78 DUF4116 PF13475.6 EAX77909.1 - 0.08 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX77909.1 - 4 7.0 23.2 0.052 13.2 5.0 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX77911.1 - 2.8e-18 65.7 34.1 1.6e-08 34.5 3.9 5.2 5 0 0 5 5 5 3 Phage tail repeat like IL2 PF00715.17 EAX77911.1 - 3.9 7.4 7.0 26 4.7 0.1 3.2 2 1 1 3 3 3 0 Interleukin 2 DUF3839 PF12943.7 EAX77912.1 - 2e-78 263.2 10.6 2.7e-78 262.8 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77912.1 - 0.19 11.6 1.6 0.53 10.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase LD_cluster2 PF18163.1 EAX77912.1 - 0.19 11.2 0.7 1.2 8.6 0.0 2.3 2 1 0 3 3 3 0 SLOG cluster2 PTR PF12789.7 EAX77913.1 - 6.1e-05 23.0 0.3 6.1e-05 23.0 0.3 3.8 4 1 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX77913.1 - 0.0053 16.6 5.4 0.0079 16.0 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX77913.1 - 0.12 12.1 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX77913.1 - 0.17 12.3 1.0 0.66 10.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX77913.1 - 0.95 9.0 14.9 20 4.7 14.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX77914.1 - 2.1e-41 140.2 0.6 4.3e-41 139.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77914.1 - 0.021 15.4 0.1 0.054 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX77915.1 - 2.1e-06 28.2 0.2 4.2e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Amidase02_C PF12123.8 EAX77916.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX77917.1 - 5.4e-23 80.8 8.8 1.7e-16 60.0 1.9 4.6 5 1 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX77917.1 - 0.086 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX77917.1 - 0.34 10.9 4.8 2.4 8.1 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) Pox_A32 PF04665.12 EAX77918.1 - 5.5e-05 22.8 1.9 5.5e-05 22.8 1.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX77918.1 - 0.0061 16.6 0.7 0.011 15.8 0.1 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX77918.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DNA_pol_B_2 PF03175.13 EAX77919.1 - 2.9e-14 52.8 1.6 3.5e-14 52.5 1.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4378 PF14309.6 EAX77920.1 - 0.002 18.5 0.0 0.013 15.9 0.0 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4378) La PF05383.17 EAX77920.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 La domain Pox_A32 PF04665.12 EAX77921.1 - 5.8e-07 29.2 2.4 5.8e-07 29.2 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX77921.1 - 2.8e-05 24.4 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX77921.1 - 7.2e-05 22.6 0.2 0.37 10.5 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX77921.1 - 0.00012 22.1 2.9 0.0003 20.8 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77921.1 - 0.00056 19.7 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX77921.1 - 0.0012 18.7 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX77921.1 - 0.0018 17.9 0.3 0.013 15.2 0.1 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX77921.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX77921.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX77921.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX77921.1 - 0.11 13.0 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RGS12_us1 PF16613.5 EAX77922.1 - 0.33 11.3 3.4 0.52 10.6 3.4 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 Pox_D5 PF03288.16 EAX77923.1 - 0.00011 22.7 2.8 0.0005 20.5 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX77923.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX77924.1 - 9.1e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX77924.1 - 0.11 12.8 0.1 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DNA_pol_B_2 PF03175.13 EAX77925.1 - 8.2e-31 107.4 12.0 5.3e-30 104.7 12.0 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX77925.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF5106 PF17127.4 EAX77925.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX77926.1 - 3.4e-126 419.6 8.4 4e-126 419.4 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX77926.1 - 0.13 11.8 0.1 0.67 9.4 0.0 2.0 1 1 1 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX77928.1 - 1.9e-154 512.1 13.5 2.3e-154 511.8 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX77928.1 - 0.45 10.8 3.7 1.7 8.9 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX77928.1 - 0.73 10.3 7.3 2.4 8.7 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX77928.1 - 5 7.5 7.8 12 6.3 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX77929.1 - 4.6e-12 45.8 0.1 6.9e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF1493 PF07377.12 EAX77930.1 - 0.049 14.1 0.7 0.1 13.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX77931.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77932.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX77933.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77933.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77933.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77933.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX77934.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX77935.1 - 6e-07 29.9 0.6 1.9e-06 28.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX77935.1 - 0.17 11.4 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DNA_pol_B_2 PF03175.13 EAX77936.1 - 3.1e-29 102.2 6.6 6.2e-29 101.2 6.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pkinase PF00069.25 EAX77937.1 - 0.00031 20.2 0.0 0.00068 19.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain T5orf172 PF10544.9 EAX77938.1 - 1.1e-06 29.1 0.2 3e-06 27.7 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX77938.1 - 0.002 17.7 0.6 0.025 14.1 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX77938.1 - 0.011 15.6 0.2 0.058 13.2 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX77939.1 - 2.9e-25 89.1 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX77941.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX77942.1 - 0.77 9.7 2.7 1.7 8.6 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4710 PF15828.5 EAX77943.1 - 0.018 15.2 1.0 0.03 14.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Pox_D5 PF03288.16 EAX77944.1 - 2.3e-05 24.8 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX77944.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX77944.1 - 0.057 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain CREPT PF16566.5 EAX77945.1 - 0.012 15.8 0.3 0.021 15.0 0.3 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AMH_N PF04709.12 EAX77945.1 - 0.078 11.9 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Fib_alpha PF08702.10 EAX77945.1 - 0.2 11.8 2.8 0.26 11.5 2.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3839 PF12943.7 EAX77947.1 - 1.1e-18 67.6 3.5 1.6e-18 67.0 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX77947.1 - 0.073 13.4 1.8 0.2 12.0 0.1 2.2 1 1 1 2 2 2 0 PRD domain T5orf172 PF10544.9 EAX77948.1 - 0.00046 20.7 0.1 0.0012 19.4 0.1 1.7 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX77948.1 - 0.0048 16.5 0.6 0.099 12.2 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX77948.1 - 0.028 13.7 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 ResIII PF04851.15 EAX77949.1 - 2e-05 24.6 0.5 3.1e-05 24.0 0.5 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX77949.1 - 0.00029 20.6 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX77949.1 - 0.00043 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX77949.1 - 0.002 17.9 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX77949.1 - 0.0069 16.7 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX77949.1 - 0.032 13.7 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX77949.1 - 0.08 12.6 0.2 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX77949.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX77949.1 - 0.091 12.3 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX77949.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX77949.1 - 0.26 10.8 2.4 0.13 11.8 0.5 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase DNA_pol_B_2 PF03175.13 EAX77951.1 - 1.7e-09 37.1 3.0 1.2e-08 34.3 3.1 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX77951.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX77951.1 - 0.11 12.5 0.0 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX77952.1 - 5.1e-79 265.1 10.8 6.5e-79 264.8 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX77952.1 - 0.19 11.5 1.4 0.74 9.7 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX77953.1 - 5.2e-73 244.6 3.6 6.8e-73 244.2 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX77954.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX77954.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX77957.1 - 5.7e-25 87.4 1.0 1e-24 86.5 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX77957.1 - 0.74 10.6 2.8 12 6.6 0.2 2.9 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF2897 PF11446.8 EAX77958.1 - 1.2 9.0 5.9 1.8 8.5 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX77959.1 - 1.4e-56 190.4 7.5 1.6e-56 190.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX77961.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX77961.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX77961.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX77961.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4107 PF13389.6 EAX77964.1 - 1.4e-72 243.1 3.8 1.9e-72 242.7 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX77965.1 - 8.8e-17 61.1 3.1 1.5e-16 60.4 3.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX77965.1 - 0.35 10.9 4.1 1.3 9.1 0.5 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5065) Pox_A32 PF04665.12 EAX77967.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX77967.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DNA_pol_B_2 PF03175.13 EAX77968.1 - 2.5e-38 132.1 14.7 1.3e-37 129.8 14.7 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAX77969.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TMP PF05017.14 EAX77971.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77972.1 - 0.055 13.4 0.8 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX77973.1 - 2.7e-11 43.3 0.8 6.8e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Autophagy_N PF03986.13 EAX77974.1 - 0.0011 18.9 0.5 0.29 11.1 0.0 2.5 1 1 2 3 3 3 2 Autophagocytosis associated protein (Atg3), N-terminal domain SVS_QK PF10578.9 EAX77974.1 - 0.0038 17.6 7.5 1 10.1 0.2 3.4 3 0 0 3 3 3 2 Seminal vesicle protein repeat LBR_tudor PF09465.10 EAX77976.1 - 0.00024 20.8 0.3 0.00045 20.0 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX77976.1 - 0.033 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor KilA-N PF04383.13 EAX77977.1 - 6.2e-40 135.5 0.5 1.3e-39 134.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX77977.1 - 0.013 16.1 0.2 0.036 14.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF1493 PF07377.12 EAX77978.1 - 0.019 15.4 0.7 0.039 14.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX77979.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX77980.1 - 0.19 11.6 2.7 0.21 11.5 0.3 2.1 2 1 0 2 2 2 0 PSP PadR PF03551.14 EAX77981.1 - 0.17 11.9 0.0 0.8 9.7 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family FAS_N PF17828.1 EAX77983.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX77984.1 - 0.024 15.0 1.1 0.027 14.9 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX77984.1 - 1.3 8.0 3.5 1.4 7.9 3.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX77984.1 - 1.7 8.6 6.7 2 8.4 6.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAX77985.1 - 0.044 13.8 0.8 0.056 13.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_MLP1_2 PF07926.12 EAX77988.1 - 0.011 15.8 0.8 0.014 15.5 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX77988.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX77989.1 - 2e-146 485.9 11.8 2.7e-146 485.4 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX77989.1 - 0.026 15.0 1.0 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 Fez1 GCN5L1 PF06320.13 EAX77989.1 - 0.067 13.4 1.6 0.92 9.7 0.0 3.2 4 0 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) Rx_N PF18052.1 EAX77989.1 - 0.69 10.2 3.8 3.4 8.0 0.0 3.3 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX77989.1 - 0.87 10.1 5.5 2.6 8.6 1.0 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX77989.1 - 1 9.7 4.3 27 5.1 0.0 3.2 3 1 0 3 3 3 0 Tup N-terminal DUF4108 PF13390.6 EAX77991.1 - 7.4e-58 194.5 5.2 8.2e-58 194.4 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Chlam_PMP PF02415.17 EAX77993.1 - 0.00014 22.1 32.6 0.13 12.8 1.2 5.4 6 1 0 6 6 6 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4795 PF16043.5 EAX77996.1 - 0.044 13.4 3.2 0.16 11.5 3.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX77996.1 - 0.26 11.4 9.5 0.14 12.2 2.5 3.2 3 1 0 3 3 3 0 Phage tail repeat like Synaptobrevin PF00957.21 EAX77997.1 - 0.00084 19.1 0.4 0.0011 18.8 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.9 EAX77997.1 - 0.09 12.7 0.2 0.097 12.5 0.2 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3467 PF11950.8 EAX77998.1 - 0.17 12.1 1.0 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DUF3574 PF12098.8 EAX77998.1 - 0.18 11.6 1.2 0.26 11.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) PTR PF12789.7 EAX77999.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX77999.1 - 1.5 9.4 4.1 13 6.4 1.7 2.7 2 1 1 3 3 3 0 YmaF family KilA-N PF04383.13 EAX78001.1 - 2.2e-42 143.4 0.2 3.4e-42 142.8 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX78002.1 - 9.9e-07 29.3 0.2 2.4e-06 28.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX78002.1 - 0.00057 19.2 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX78002.1 - 0.0094 15.5 0.7 0.098 12.2 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX78002.1 - 0.028 14.3 0.4 0.22 11.3 0.1 2.3 2 1 0 2 2 2 0 KilA-N domain T5orf172 PF10544.9 EAX78003.1 - 0.001 19.6 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX78003.1 - 0.0039 16.8 0.3 0.009 15.6 0.1 1.6 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX78003.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain Pox_D5 PF03288.16 EAX78004.1 - 6e-05 23.5 2.8 0.00035 21.0 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX78005.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78005.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PBP_sp32 PF07222.12 EAX78006.1 - 1.1 8.7 7.7 1.6 8.2 7.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PcfK PF14058.6 EAX78006.1 - 2.5 8.4 14.9 3.8 7.8 14.9 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF3839 PF12943.7 EAX78007.1 - 1.4e-123 411.0 7.4 1.6e-123 410.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_D5 PF03288.16 EAX78008.1 - 5.2e-05 23.6 2.9 0.00029 21.3 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX78008.1 - 0.038 13.1 1.1 0.054 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX78009.1 - 6.3e-63 211.0 8.4 7.1e-63 210.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX78010.1 - 2.1e-155 515.3 12.7 2.6e-155 514.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78010.1 - 0.17 12.4 5.4 5.2 7.6 0.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX78010.1 - 0.21 12.2 3.5 0.78 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Ribosomal_S6e PF01092.19 EAX78012.1 - 0.061 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S6e HECT_2 PF09814.9 EAX78014.1 - 0.0016 17.4 4.7 0.04 12.8 0.3 2.6 1 1 2 3 3 3 3 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Herpes_LP PF03363.13 EAX78014.1 - 8.2 6.2 13.3 1.4 8.7 0.4 3.4 2 2 2 4 4 4 0 Herpesvirus leader protein T5orf172 PF10544.9 EAX78016.1 - 0.0019 18.7 0.0 0.0039 17.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78016.1 - 0.0095 15.8 0.3 0.022 14.6 0.3 1.8 1 1 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX78017.1 - 2.6e-07 30.3 1.2 4.4e-07 29.6 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PSP PF04046.16 EAX78018.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX78019.1 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX78020.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX78021.1 - 2.6e-06 27.9 0.0 6.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78021.1 - 0.0036 17.2 0.1 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain FRG PF08867.11 EAX78021.1 - 0.059 14.3 0.1 1 10.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain DUF3839 PF12943.7 EAX78022.1 - 1.3e-21 77.2 3.9 1.9e-21 76.7 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) BrkDBD PF09607.10 EAX78022.1 - 0.22 11.3 1.8 0.28 11.0 1.0 1.6 2 0 0 2 2 2 0 Brinker DNA-binding domain PSP PF04046.16 EAX78023.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX78024.1 - 0.024 15.1 0.6 0.046 14.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX78025.1 - 4.7e-66 221.9 12.9 2.2e-64 216.5 12.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX78026.1 - 0.09 13.4 2.2 37 5.6 0.1 3.6 3 0 0 3 3 3 0 TMP repeat DUF3781 PF12636.7 EAX78027.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Amidase02_C PF12123.8 EAX78028.1 - 0.0011 18.5 0.1 0.0034 17.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX78029.1 - 0.0021 17.7 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78029.1 - 0.13 12.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX78030.1 - 1.7e-07 30.9 0.4 1.4e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein TK PF00265.18 EAX78030.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX78030.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX78032.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78033.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX78034.1 - 5.2e-54 183.3 5.1 6.8e-54 182.9 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX78034.1 - 0.096 13.2 0.3 0.12 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX78036.1 - 2.2e-23 82.1 11.1 2.2e-23 82.1 11.1 4.3 4 1 0 4 4 4 1 Phage tail repeat like DUF3781 PF12636.7 EAX78037.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX78038.1 - 2.1e-66 223.1 12.3 1.4e-65 220.4 12.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX78039.1 - 1.9e-17 63.1 1.2 3.4e-17 62.3 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78039.1 - 0.031 14.9 0.0 0.07 13.8 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX78040.1 - 8e-07 28.8 2.5 8e-07 28.8 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78040.1 - 3.2e-05 23.7 0.4 0.3 10.8 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78040.1 - 6.8e-05 23.2 0.2 0.00054 20.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78040.1 - 0.00037 20.5 4.5 0.00089 19.3 4.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78040.1 - 0.00071 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78040.1 - 0.0025 17.6 1.4 0.0043 16.9 0.9 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78040.1 - 0.0074 16.0 3.2 0.016 14.9 0.6 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78040.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX78040.1 - 0.086 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX78040.1 - 0.092 12.3 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78040.1 - 0.096 13.1 0.1 0.93 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78040.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78040.1 - 0.44 10.8 4.9 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX78040.1 - 0.74 10.5 11.9 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAX78042.1 - 4.1e-54 182.4 6.1 4.6e-54 182.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Herpes_IE2_3 PF03361.14 EAX78043.1 - 0.017 15.0 0.8 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX78043.1 - 0.036 14.3 4.7 4.4 7.7 0.1 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region Pox_A32 PF04665.12 EAX78044.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4795 PF16043.5 EAX78046.1 - 0.0025 17.5 15.5 0.3 10.7 7.7 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Phasin PF05597.11 EAX78046.1 - 0.0073 16.3 5.5 0.0079 16.2 0.7 2.9 3 0 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 EAX78046.1 - 0.011 15.8 11.6 0.1 12.6 2.0 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF1-HH PF16275.5 EAX78046.1 - 0.017 15.4 0.7 0.1 12.9 0.1 2.4 2 1 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Lip_prot_lig_C PF10437.9 EAX78046.1 - 0.025 14.5 4.3 0.37 10.8 0.2 3.2 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Apolipoprotein PF01442.18 EAX78046.1 - 0.028 14.3 4.5 2.4 8.0 4.6 3.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EAX78046.1 - 0.038 14.1 10.9 0.37 10.9 1.8 2.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GvpG PF05120.12 EAX78046.1 - 0.14 12.2 2.4 0.42 10.6 0.0 2.6 3 0 0 3 3 3 0 Gas vesicle protein G ARD PF03079.14 EAX78046.1 - 0.25 11.5 6.5 0.55 10.4 1.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Tmpp129 PF10272.9 EAX78046.1 - 0.34 10.2 2.1 0.5 9.6 2.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Arg_decarbox_C PF17944.1 EAX78046.1 - 0.53 10.9 0.2 0.53 10.9 0.2 2.7 4 0 0 4 4 2 0 Arginine decarboxylase C-terminal helical extension DNA_primase_lrg PF04104.14 EAX78046.1 - 0.59 9.5 5.2 0.97 8.8 0.1 2.6 1 1 1 3 3 3 0 Eukaryotic and archaeal DNA primase, large subunit Prominin PF05478.11 EAX78046.1 - 0.78 7.6 9.0 0.29 9.0 2.6 1.7 1 1 0 1 1 1 0 Prominin AI-2E_transport PF01594.16 EAX78046.1 - 1 8.4 3.6 1.3 8.1 0.1 2.4 1 1 2 3 3 3 0 AI-2E family transporter Cep57_CLD_2 PF14197.6 EAX78046.1 - 1.1 9.4 5.8 3.9 7.6 1.0 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DNA_repr_REX1B PF14966.6 EAX78046.1 - 1.1 9.9 4.8 6 7.6 0.1 2.8 1 1 1 3 3 3 0 DNA repair REX1-B Allexi_40kDa PF05549.11 EAX78046.1 - 1.3 8.5 8.1 5.4 6.4 2.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DASH_Dad1 PF08649.10 EAX78046.1 - 1.3 9.2 5.2 2.4 8.4 0.3 3.4 4 0 0 4 4 4 0 DASH complex subunit Dad1 DUF1664 PF07889.12 EAX78046.1 - 1.4 8.9 11.9 0.39 10.8 2.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EAX78046.1 - 1.5 9.0 7.6 12 6.1 0.9 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation SlyX PF04102.12 EAX78046.1 - 2.2 9.0 7.0 6.3 7.5 0.3 3.3 3 1 1 4 4 4 0 SlyX DUF4094 PF13334.6 EAX78046.1 - 2.9 8.4 7.6 4.5 7.8 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TMPIT PF07851.13 EAX78046.1 - 4.8 6.3 7.7 3.2 6.9 1.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein ResIII PF04851.15 EAX78047.1 - 2.2e-05 24.5 0.1 2.9e-05 24.1 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78047.1 - 0.00036 20.3 0.0 0.00048 19.9 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78047.1 - 0.0015 18.3 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX78047.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78047.1 - 0.0052 17.1 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX78047.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX78047.1 - 0.058 13.1 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX78047.1 - 0.068 12.7 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX78047.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX78048.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78048.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX78048.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX78048.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78048.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX78048.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) KilA-N PF04383.13 EAX78049.1 - 1.8e-18 66.4 1.3 3e-18 65.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78049.1 - 0.0035 17.9 0.0 0.0077 16.8 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Peptidase_C1 PF00112.23 EAX78050.1 - 4.4e-46 157.7 4.5 5.7e-46 157.3 4.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX78050.1 - 4.3e-09 36.7 0.1 6.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) MULE PF10551.9 EAX78051.1 - 6.1e-14 52.2 2.9 6.3e-14 52.2 0.4 2.1 2 1 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX78051.1 - 0.03 14.1 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EAX78051.1 - 0.078 11.8 0.1 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family TMP PF05017.14 EAX78053.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX78055.1 - 9.3e-157 519.7 13.8 1.2e-156 519.4 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX78055.1 - 0.057 13.5 0.2 0.33 11.1 0.1 2.3 2 0 0 2 2 2 0 Associated with zinc fingers KELK PF15796.5 EAX78055.1 - 1.6 9.2 8.5 2.5 8.6 1.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX78056.1 - 1.8e-24 85.6 13.3 1.8e-24 85.6 13.3 3.5 3 1 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX78056.1 - 0.058 13.1 1.0 0.097 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DNA_pol_B_2 PF03175.13 EAX78057.1 - 2.2e-31 109.2 12.2 5.1e-31 108.1 12.2 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX78059.1 - 5.8e-26 91.4 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX78061.1 - 1.6e-118 394.5 10.7 1.8e-118 394.3 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78061.1 - 0.07 13.6 3.1 0.42 11.1 1.6 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX78061.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase LD_cluster2 PF18163.1 EAX78061.1 - 0.17 11.4 0.1 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX78063.1 - 5.9e-07 29.2 2.2 5.9e-07 29.2 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78063.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78063.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78063.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78063.1 - 0.00063 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX78063.1 - 0.0014 18.3 0.4 0.0097 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78063.1 - 0.0015 18.4 0.7 0.0041 16.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78063.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX78063.1 - 0.072 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78063.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78063.1 - 0.097 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX78063.1 - 0.15 12.4 2.9 0.73 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX78063.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX78065.1 - 0.014 15.3 0.1 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX78067.1 - 4.9e-80 268.5 11.6 6.5e-80 268.1 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78067.1 - 0.071 12.6 0.7 0.27 10.7 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX78067.1 - 0.098 13.2 0.5 0.16 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX78067.1 - 0.12 12.7 1.3 0.31 11.4 0.1 2.3 3 0 0 3 3 3 0 PRD domain Pox_A32 PF04665.12 EAX78068.1 - 2.2e-07 30.6 2.6 3.2e-07 30.1 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78068.1 - 0.0045 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78068.1 - 0.056 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78068.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78068.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78068.1 - 0.51 10.6 8.3 5.7 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF4106 PF13388.6 EAX78069.1 - 9.9e-275 911.2 21.6 1.2e-274 910.9 21.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78069.1 - 0.00062 20.0 0.2 0.032 14.5 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated T5orf172 PF10544.9 EAX78070.1 - 6.3e-06 26.7 0.1 1.5e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78070.1 - 0.0061 16.4 0.1 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain VirE PF05272.11 EAX78071.1 - 0.0002 21.1 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX78071.1 - 0.047 14.1 0.1 0.087 13.2 0.1 1.5 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 EAX78071.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.3 1 1 2 3 3 3 0 Poxvirus A32 protein KilA-N PF04383.13 EAX78072.1 - 3.2e-16 59.2 0.4 1e-15 57.5 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX78073.1 - 7.8e-08 32.1 0.5 8.6e-08 31.9 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78073.1 - 0.0076 15.9 0.1 0.008 15.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX78073.1 - 0.056 13.4 0.4 0.52 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX78073.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PadR PF03551.14 EAX78074.1 - 0.11 12.5 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family KilA-N PF04383.13 EAX78076.1 - 3.6e-39 133.1 0.2 1e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78076.1 - 0.009 16.2 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) CBF PF03914.17 EAX78076.1 - 0.17 11.9 0.5 0.4 10.7 0.1 1.6 1 1 1 2 2 2 0 CBF/Mak21 family PcfK PF14058.6 EAX78077.1 - 0.021 15.1 5.9 0.029 14.7 5.9 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX78077.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX78078.1 - 2.2e-62 209.2 8.6 2.5e-62 209.0 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78078.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX78079.1 - 9.8e-05 22.8 3.6 0.00089 19.7 3.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78079.1 - 0.065 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78079.1 - 0.087 12.8 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4107 PF13389.6 EAX78080.1 - 2e-55 187.3 1.1 2.7e-55 186.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDR PF08841.10 EAX78082.1 - 0.099 11.6 0.2 0.095 11.7 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX78082.1 - 0.31 11.5 3.2 0.37 11.2 3.2 1.3 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX78083.1 - 0.016 15.2 9.8 0.023 14.7 9.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HTH_Tnp_4 PF13613.6 EAX78085.1 - 9e-06 25.3 0.8 0.0005 19.7 0.5 2.2 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease DUF4108 PF13390.6 EAX78086.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Adaptin_N PF01602.20 EAX78087.1 - 5e-06 25.4 2.1 5e-06 25.4 2.1 2.4 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 EAX78087.1 - 7.2e-06 26.3 3.1 0.022 15.1 0.2 4.4 3 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EAX78087.1 - 1e-05 25.9 0.8 2.1 8.9 0.0 4.4 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EAX78087.1 - 1.5e-05 24.9 0.1 0.11 12.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 EAX78087.1 - 6.8e-05 22.8 0.2 0.15 12.1 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAX78087.1 - 0.00089 19.3 9.1 0.0097 16.0 2.2 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RRF PF01765.19 EAX78087.1 - 0.0059 16.6 2.5 0.92 9.4 0.1 3.1 2 1 0 2 2 2 1 Ribosome recycling factor Tht1 PF04163.12 EAX78087.1 - 0.0083 14.9 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein V-ATPase_H_C PF11698.8 EAX78087.1 - 0.029 14.5 0.5 0.15 12.2 0.5 2.2 1 0 0 1 1 1 0 V-ATPase subunit H Transposase_31 PF04754.12 EAX78087.1 - 0.06 12.9 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative transposase, YhgA-like CLASP_N PF12348.8 EAX78087.1 - 0.11 12.0 1.4 2.9 7.4 0.1 3.1 2 2 0 2 2 2 0 CLASP N terminal FANCI_S2 PF14676.6 EAX78087.1 - 4.5 7.6 5.9 3.1 8.1 0.7 3.0 3 2 0 3 3 3 0 FANCI solenoid 2 PTR PF12789.7 EAX78088.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.7 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX78088.1 - 0.027 14.2 0.1 0.1 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX78088.1 - 0.089 11.8 0.7 0.16 10.9 0.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX78088.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX78088.1 - 1.2 8.9 10.4 1.2 8.9 9.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX78088.1 - 1.4 8.5 22.1 0.089 12.4 6.0 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TbpB_A PF17484.2 EAX78088.1 - 6.4 7.5 7.8 11 6.8 6.2 2.3 3 1 0 3 3 3 0 N-Lobe handle Tf-binding protein B Pox_A32 PF04665.12 EAX78089.1 - 8e-07 28.8 3.0 8e-07 28.8 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78089.1 - 2.8e-05 24.4 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78089.1 - 2.9e-05 24.1 3.8 6.7e-05 23.0 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX78089.1 - 6.6e-05 22.7 0.3 0.35 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX78089.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78089.1 - 0.0012 18.7 0.4 0.0022 17.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78089.1 - 0.002 17.8 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78089.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78089.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX78089.1 - 0.099 12.1 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78089.1 - 0.11 13.0 0.1 0.86 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78089.1 - 0.36 11.1 3.8 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX78090.1 - 0.00013 22.3 2.4 0.00069 20.1 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX78091.1 - 3.5e-64 215.0 6.6 3.9e-64 214.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Cytadhesin_P30 PF07271.11 EAX78093.1 - 1.9 8.0 18.6 2.4 7.7 18.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Amidase02_C PF12123.8 EAX78094.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX78095.1 - 1.6e-140 466.6 9.8 1.8e-140 466.3 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX78095.1 - 0.038 14.2 0.2 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 Rx_N PF18052.1 EAX78095.1 - 0.069 13.4 0.2 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Rx N-terminal domain FAS_N PF17828.1 EAX78097.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX78098.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78098.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX78098.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX78098.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GPS2_interact PF15784.5 EAX78100.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX78101.1 - 7.5e-05 22.3 3.5 0.00014 21.5 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX78101.1 - 0.0055 16.7 0.9 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX78101.1 - 0.0094 15.6 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX78101.1 - 0.052 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3447 PF11929.8 EAX78102.1 - 6.3e-14 51.7 2.5 1.3e-13 50.7 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) PSP PF04046.16 EAX78103.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX78104.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX78105.1 - 0.03 14.8 0.8 0.063 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPS2_interact PF15784.5 EAX78106.1 - 0.64 10.5 4.3 1.1 9.8 4.3 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX78107.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX78107.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1493 PF07377.12 EAX78108.1 - 0.022 15.2 1.9 0.023 15.1 0.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX78111.1 - 1e-07 31.7 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78112.1 - 7.6e-05 23.2 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78112.1 - 0.0042 16.9 0.5 0.016 15.0 0.3 2.2 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX78114.1 - 2e-146 485.9 9.9 2.3e-146 485.7 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX78114.1 - 0.11 12.7 0.3 4.7 7.5 0.0 2.9 3 0 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX78114.1 - 0.11 12.3 0.3 0.24 11.2 0.2 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase zf-ribbon_3 PF13248.6 EAX78115.1 - 0.047 13.1 3.2 4.1 7.0 0.3 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Rpr2 PF04032.16 EAX78115.1 - 0.12 12.7 4.0 1.9 8.8 0.3 2.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Fer4_22 PF17179.4 EAX78115.1 - 0.12 13.2 0.8 19 6.2 0.0 3.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain zinc_ribbon_2 PF13240.6 EAX78115.1 - 0.23 11.2 3.6 12 5.8 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CarbpepA_inh PF02977.15 EAX78115.1 - 1.6 8.6 6.6 6.1 6.7 0.2 3.3 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor PapD_N PF00345.20 EAX78117.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain GPS2_interact PF15784.5 EAX78119.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78119.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX78121.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase ZapB PF06005.12 EAX78123.1 - 0.0068 16.8 7.6 0.3 11.6 0.3 3.2 2 1 1 3 3 3 2 Cell division protein ZapB DivIC PF04977.15 EAX78123.1 - 0.022 14.5 4.3 2.5 7.9 0.8 2.6 2 1 0 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.13 EAX78123.1 - 0.037 14.7 3.1 0.24 12.1 0.7 2.9 2 1 0 2 2 2 0 Occludin homology domain GIT_CC PF16559.5 EAX78123.1 - 0.052 13.4 5.5 1.6 8.7 0.0 3.7 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2205 PF10224.9 EAX78123.1 - 0.072 13.1 4.4 0.33 11.0 0.6 3.0 2 1 1 3 3 3 0 Short coiled-coil protein DUF2524 PF10732.9 EAX78123.1 - 0.074 13.4 1.1 0.18 12.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) V_ATPase_I PF01496.19 EAX78123.1 - 0.12 10.3 2.8 0.12 10.3 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EAX78123.1 - 0.14 12.7 6.7 0.091 13.3 2.7 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Mito_fiss_reg PF05308.11 EAX78123.1 - 0.38 10.8 3.2 1.2 9.2 1.5 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator NusA_N PF08529.11 EAX78123.1 - 0.43 10.9 7.1 1.8 8.9 2.2 2.4 2 1 0 2 2 2 0 NusA N-terminal domain DUF4841 PF16129.5 EAX78124.1 - 0.07 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) Pox_A32 PF04665.12 EAX78125.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78125.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78125.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78125.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78126.1 - 1.3e-113 378.4 10.4 1.7e-113 378.1 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78126.1 - 0.013 15.9 2.7 1.9 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78127.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78127.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78127.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78127.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78127.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78127.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78127.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX78128.1 - 6.5e-08 32.3 1.9 7.3e-08 32.2 1.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78128.1 - 0.011 15.4 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX78128.1 - 0.022 14.8 1.1 0.05 13.6 1.0 1.6 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX78128.1 - 0.029 14.1 0.1 0.07 12.9 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78128.1 - 0.066 13.2 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) RNA_helicase PF00910.22 EAX78128.1 - 0.1 13.0 0.1 0.26 11.7 0.0 1.7 1 1 0 2 2 2 0 RNA helicase DUF3839 PF12943.7 EAX78129.1 - 1.3e-153 509.4 11.9 1.6e-153 509.1 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78129.1 - 1.1 9.7 4.9 6.3 7.3 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78130.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78130.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78130.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78130.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78130.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78130.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78130.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX78131.1 - 1.6e-53 181.7 4.6 2.1e-53 181.3 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX78131.1 - 0.042 14.4 0.6 0.053 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX78131.1 - 0.042 14.3 0.3 0.049 14.1 0.3 1.2 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 EAX78131.1 - 0.12 12.8 0.9 0.73 10.3 0.1 2.4 3 0 0 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX78131.1 - 0.4 11.1 2.3 1.1 9.7 1.1 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain PapD_N PF00345.20 EAX78133.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PTR PF12789.7 EAX78134.1 - 9.2e-23 80.1 13.7 8.4e-17 61.0 1.6 3.8 4 0 0 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX78134.1 - 2.5 8.7 18.8 1.3 9.6 3.1 4.2 2 2 0 2 2 2 0 YmaF family MULE PF10551.9 EAX78135.1 - 8.6e-10 38.9 0.3 1.9e-09 37.8 0.3 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX78135.1 - 0.016 15.0 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EAX78135.1 - 0.039 12.8 0.1 0.058 12.2 0.1 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF1196 PF06709.11 EAX78135.1 - 0.61 10.3 2.2 2.2 8.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1196) O-antigen_lig PF13425.6 EAX78136.1 - 0.6 8.8 2.9 0.72 8.6 2.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Spo12 PF05032.12 EAX78138.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family TPR_MLP1_2 PF07926.12 EAX78139.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX78139.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX78139.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX78140.1 - 5.7e-07 30.0 0.4 1.1e-06 29.1 0.4 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF4106 PF13388.6 EAX78141.1 - 1.4e-84 284.7 6.2 1.4e-84 284.7 6.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX78142.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78142.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78142.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78142.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78142.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78142.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78142.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pax7 PF12360.8 EAX78143.1 - 0.13 12.5 0.2 9.3 6.5 0.0 2.1 1 1 1 2 2 2 0 Paired box protein 7 OrfB_IS605 PF01385.19 EAX78143.1 - 0.14 12.4 0.2 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Probable transposase DUF3839 PF12943.7 EAX78144.1 - 1.5e-63 214.5 4.0 1.7e-63 214.4 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78144.1 - 0.034 13.6 0.4 0.039 13.5 0.4 1.0 1 0 0 1 1 1 0 Z1 domain DUF4108 PF13390.6 EAX78146.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DPM3 PF08285.11 EAX78147.1 - 0.16 12.1 0.7 2.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pox_D5 PF03288.16 EAX78148.1 - 7.3e-05 23.2 2.9 0.00034 21.1 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78148.1 - 0.027 15.1 0.1 0.057 14.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78148.1 - 0.069 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX78149.1 - 1.3e-58 197.0 5.3 1.4e-58 196.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78149.1 - 0.1 12.8 0.1 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX78150.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF5365 PF17326.2 EAX78152.1 - 0.02 15.3 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF1493 PF07377.12 EAX78153.1 - 0.023 15.2 0.5 0.041 14.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX78154.1 - 0.046 14.3 4.8 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX78155.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX78156.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78157.1 - 0.0021 18.6 0.1 0.0041 17.6 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78157.1 - 0.012 15.5 1.0 0.041 13.7 1.0 2.0 1 1 0 1 1 1 0 KilA-N domain T5orf172 PF10544.9 EAX78158.1 - 4.3e-07 30.4 0.4 8.6e-07 29.5 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX78161.1 - 0.038 14.4 0.7 0.078 13.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX78162.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX78165.1 - 2.2e-06 28.2 0.1 5.3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78165.1 - 0.0089 15.9 0.3 0.038 13.8 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX78165.1 - 0.011 15.2 1.0 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Helicase_C PF00271.31 EAX78166.1 - 1.9e-07 31.4 6.0 3.8e-06 27.2 6.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAX78166.1 - 3e-07 30.4 0.0 8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX78166.1 - 1.8e-06 28.1 3.9 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cnd1_N PF12922.7 EAX78166.1 - 0.075 12.9 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Toxin_TOLIP PF00087.21 EAX78166.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Snake toxin and toxin-like protein HA2 PF04408.23 EAX78166.1 - 1 9.7 2.9 15 5.9 0.2 2.5 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF4106 PF13388.6 EAX78167.1 - 1.3e-293 973.3 23.6 1.9e-293 972.8 23.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78167.1 - 0.00081 19.7 0.1 0.038 14.3 0.2 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated T5orf172 PF10544.9 EAX78168.1 - 0.00034 21.1 0.0 0.00075 20.0 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78168.1 - 0.019 14.8 0.9 0.048 13.5 0.9 1.8 1 1 0 1 1 1 0 KilA-N domain Trypan_PARP PF05887.11 EAX78169.1 - 0.095 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX78170.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX78171.1 - 8.9e-144 477.2 13.4 1.1e-143 476.9 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78171.1 - 0.064 13.7 4.7 1.6 9.2 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78172.1 - 6e-08 32.4 1.0 6.9e-08 32.3 1.0 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78172.1 - 0.0047 16.6 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78172.1 - 0.064 13.0 0.0 0.094 12.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78172.1 - 0.065 13.2 0.4 0.6 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Ank_4 PF13637.6 EAX78173.1 - 6.1e-06 26.7 0.0 8.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX78173.1 - 0.00051 20.6 0.0 0.00063 20.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX78173.1 - 0.0023 18.3 0.1 0.9 10.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX78173.1 - 0.03 14.8 0.0 7.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat LRR_5 PF13306.6 EAX78174.1 - 8.3e-43 145.4 23.2 2.9e-24 85.4 9.5 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX78174.1 - 1.9e-06 27.5 0.1 0.024 14.4 0.0 3.1 1 1 2 3 3 3 2 Leucine rich repeat KilA-N PF04383.13 EAX78175.1 - 1.5e-16 60.2 1.2 2.6e-16 59.4 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78175.1 - 0.031 14.9 0.0 0.063 13.9 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX78176.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78176.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78176.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78176.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3781 PF12636.7 EAX78178.1 - 0.029 14.3 0.8 0.05 13.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) PapD_N PF00345.20 EAX78179.1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX78180.1 - 0.017 15.5 0.5 0.024 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4107 PF13389.6 EAX78181.1 - 2.4e-70 235.9 3.2 3e-70 235.6 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78181.1 - 0.094 13.1 1.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DDE_Tnp_4 PF13359.6 EAX78182.1 - 1.3e-31 109.4 0.0 2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX78182.1 - 1.6e-08 34.5 0.1 7.7e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain Pox_A32 PF04665.12 EAX78184.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78184.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78184.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78184.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78184.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78184.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78184.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX78185.1 - 3e-40 138.2 5.0 4.2e-40 137.7 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78185.1 - 0.086 12.4 0.2 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX78185.1 - 0.1 13.1 0.4 0.12 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spo12 PF05032.12 EAX78186.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX78188.1 - 8.4e-63 210.6 8.3 9.4e-63 210.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX78190.1 - 1.1e-06 28.3 2.3 1.1e-06 28.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78190.1 - 2.7e-05 24.0 0.2 0.21 11.3 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78190.1 - 8.8e-05 22.8 0.2 0.00055 20.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78190.1 - 0.00017 21.6 3.4 0.00041 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78190.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX78190.1 - 0.0013 18.4 0.4 0.0085 15.8 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78190.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78190.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78190.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78190.1 - 0.084 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78190.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78190.1 - 0.37 11.1 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX78192.1 - 1.1e-94 316.5 8.4 1.2e-94 316.3 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78192.1 - 0.032 13.7 0.3 0.037 13.5 0.3 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX78192.1 - 0.32 11.6 2.6 0.36 11.5 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Pox_A32 PF04665.12 EAX78193.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78193.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX78193.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX78193.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78193.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX78193.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Pox_A32 PF04665.12 EAX78194.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78194.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78194.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78194.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78194.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78194.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78194.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX78196.1 - 4.8e-07 29.5 0.0 8.9e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX78197.1 - 4.7e-28 98.3 6.3 8.3e-28 97.5 6.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78197.1 - 0.026 13.9 0.2 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF2939 PF11159.8 EAX78198.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78198.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX78198.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX78198.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX78199.1 - 0.024 14.6 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF4108 PF13390.6 EAX78202.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX78203.1 - 3.1e-05 24.4 3.0 0.0002 21.8 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX78204.1 - 1.8e-147 489.3 13.6 2.2e-147 489.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX78204.1 - 0.09 13.1 0.4 1.9 8.8 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX78204.1 - 0.68 10.4 5.7 4.2 7.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX78206.1 - 0.0094 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX78207.1 - 0.0027 17.3 0.0 0.0091 15.7 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78207.1 - 0.12 12.2 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PapD_N PF00345.20 EAX78208.1 - 0.017 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX78210.1 - 1.3e-78 263.9 11.7 1.7e-78 263.5 11.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78210.1 - 0.079 12.5 0.3 0.21 11.1 0.0 1.9 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX78210.1 - 0.13 12.1 2.0 0.4 10.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX78211.1 - 5.1e-07 29.4 2.4 5.1e-07 29.4 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78211.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78211.1 - 4.4e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78211.1 - 0.00017 21.6 3.5 0.00036 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78211.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78211.1 - 0.0017 18.2 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78211.1 - 0.0019 17.9 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78211.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78211.1 - 0.073 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78211.1 - 0.091 13.2 0.1 0.76 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78211.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78211.1 - 0.39 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX78212.1 - 2.2e-118 394.0 6.7 2.5e-118 393.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78212.1 - 0.082 12.4 0.8 0.14 11.7 0.6 1.3 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX78212.1 - 0.22 12.0 2.5 1.3 9.5 1.3 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX78213.1 - 6.5e-15 55.0 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain PadR PF03551.14 EAX78215.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX78216.1 - 4.9e-80 268.5 11.6 6.5e-80 268.1 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78216.1 - 0.071 12.6 0.7 0.27 10.7 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX78216.1 - 0.098 13.2 0.5 0.16 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX78216.1 - 0.12 12.7 1.3 0.31 11.4 0.1 2.3 3 0 0 3 3 3 0 PRD domain Pox_A32 PF04665.12 EAX78217.1 - 2.1e-07 30.7 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78217.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78217.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78217.1 - 0.059 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX78217.1 - 0.41 10.9 8.5 5.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX78219.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78219.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78219.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78219.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Mito_fiss_reg PF05308.11 EAX78222.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX78222.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX78223.1 - 7.9e-155 513.4 12.7 1e-154 513.0 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX78223.1 - 0.22 11.8 1.3 0.51 10.7 0.2 2.2 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX78223.1 - 0.49 10.9 5.0 1.3 9.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX78223.1 - 0.88 10.1 6.2 5 7.7 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX78223.1 - 1.5 9.2 4.4 2.8 8.3 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KilA-N PF04383.13 EAX78226.1 - 8.9e-21 73.8 1.5 1.3e-20 73.3 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78226.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78227.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78227.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78227.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78227.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78227.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78227.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78227.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78227.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78227.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78227.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78227.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78227.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX78228.1 - 3.3e-07 30.8 0.4 7.1e-07 29.7 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX78228.1 - 0.1 13.3 0.6 0.29 11.8 0.6 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX78229.1 - 5.9e-33 113.1 1.0 9.5e-33 112.4 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX78229.1 - 0.0045 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX78229.1 - 0.081 13.4 4.7 0.49 10.9 1.1 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX78230.1 - 2.8e-07 30.3 1.1 1.2e-06 28.2 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX78230.1 - 0.046 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX78230.1 - 0.056 13.1 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX78230.1 - 0.064 13.1 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF1731 PF08338.11 EAX78231.1 - 0.12 12.2 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX78232.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78232.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78232.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78232.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78232.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78232.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78232.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) NMT PF01233.19 EAX78233.1 - 0.034 14.0 0.3 0.041 13.7 0.3 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Pox_A32 PF04665.12 EAX78234.1 - 3.9e-07 29.8 2.6 3.9e-07 29.8 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78234.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78234.1 - 5.5e-05 23.0 0.3 0.47 10.2 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78234.1 - 0.00016 21.7 3.4 0.00039 20.5 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78234.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78234.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78234.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78234.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78234.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78234.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78234.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78234.1 - 0.38 11.0 4.4 7.8 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX78235.1 - 1.2e-156 519.3 13.2 1.6e-156 518.9 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX78235.1 - 0.5 10.7 4.2 9.9 6.6 0.0 3.5 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX78235.1 - 0.76 10.3 3.9 5.2 7.6 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX78235.1 - 2.7 8.6 5.5 1.1 9.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX78236.1 - 2e-24 86.3 6.8 3e-24 85.7 6.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral KilA-N PF04383.13 EAX78237.1 - 7.4e-39 132.1 0.3 2e-38 130.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX78238.1 - 0.0018 18.0 0.0 0.0054 16.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78238.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) GerD PF17898.1 EAX78239.1 - 0.018 15.0 0.2 0.046 13.7 0.1 1.7 1 1 1 2 2 2 0 Spore germination GerD central core domain HTH_29 PF13551.6 EAX78239.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX78239.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DUF3839 PF12943.7 EAX78240.1 - 1.1e-128 427.7 9.5 1.3e-128 427.6 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78240.1 - 0.46 11.0 2.8 1.3 9.5 0.9 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Imm70 PF15601.6 EAX78241.1 - 0.037 13.6 18.7 9.9 5.7 0.2 5.8 1 1 7 8 8 8 0 Immunity protein 70 DUF4327 PF14217.6 EAX78242.1 - 0.027 14.6 0.4 2.7 8.2 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4327) CdiA_C_tRNase PF18664.1 EAX78242.1 - 0.12 12.6 1.8 3 8.1 0.1 2.8 1 1 1 2 2 2 0 CdiA C-terminal tRNase domain DDE_Tnp_IS1 PF03400.13 EAX78242.1 - 0.13 12.6 0.2 20 5.5 0.0 2.7 2 1 1 3 3 3 0 IS1 transposase DUF3592 PF12158.8 EAX78243.1 - 5.1 7.1 5.8 2.3 8.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) Pox_A32 PF04665.12 EAX78244.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78244.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78244.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78244.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX78245.1 - 2.5e-33 113.9 19.2 6e-32 109.5 13.5 4.6 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX78245.1 - 0.018 14.8 1.1 0.038 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2939 PF11159.8 EAX78247.1 - 0.028 14.8 0.4 0.038 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX78247.1 - 2.6 8.7 6.3 6.1 7.5 6.3 1.7 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX78248.1 - 0.013 15.5 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX78250.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX78250.1 - 0.14 12.2 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DDR PF08841.10 EAX78251.1 - 0.066 12.2 0.1 0.069 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX78251.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4107 PF13389.6 EAX78253.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX78253.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX78254.1 - 1.3e-118 394.8 11.2 1.6e-118 394.5 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX78254.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX78254.1 - 0.18 12.3 2.6 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX78255.1 - 5.5e-28 97.0 1.5 6.8e-28 96.8 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain Parathyroid PF01279.17 EAX78255.1 - 0.026 15.1 0.4 0.062 13.9 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family Amidase02_C PF12123.8 EAX78257.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78257.1 - 0.18 11.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PTR PF12789.7 EAX78258.1 - 6e-59 196.0 36.7 7.7e-34 115.6 17.4 5.4 4 2 2 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX78258.1 - 0.15 11.9 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX78258.1 - 2.3 8.6 5.8 27 5.2 0.1 3.7 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain GPS2_interact PF15784.5 EAX78259.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78259.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX78260.1 - 0.063 13.3 6.3 0.079 12.9 6.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX78260.1 - 1.5 9.2 5.0 1.9 8.9 5.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX78261.1 - 5.8e-128 425.4 8.7 6.5e-128 425.2 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78261.1 - 0.063 12.8 0.1 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX78261.1 - 0.25 11.8 2.3 1.3 9.6 1.0 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78263.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX78263.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX78263.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX78263.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 EAX78264.1 - 1.3e-28 100.1 8.7 2.3e-28 99.3 8.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78264.1 - 0.02 14.2 0.2 0.033 13.5 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX78264.1 - 0.077 13.1 2.2 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX78265.1 - 2.3e-78 263.0 10.7 2.9e-78 262.7 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78265.1 - 0.22 11.4 1.3 0.65 9.8 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase GPS2_interact PF15784.5 EAX78267.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78267.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX78269.1 - 2.2e-156 518.5 13.4 2.7e-156 518.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78269.1 - 0.22 11.0 5.7 0.083 12.4 0.7 2.3 1 1 2 3 3 3 0 Z1 domain KELK PF15796.5 EAX78269.1 - 0.74 10.3 8.0 0.91 10.0 1.0 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX78272.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX78272.1 - 0.072 13.1 0.7 0.1 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) KilA-N PF04383.13 EAX78273.1 - 6.5e-24 83.9 1.1 1.1e-23 83.2 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX78273.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78274.1 - 7.2e-05 22.4 0.4 8.2e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX78274.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase PapD_N PF00345.20 EAX78276.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX78276.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DHR10 PF18595.1 EAX78278.1 - 0.013 15.5 3.9 0.96 9.5 1.7 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF5521 PF17659.1 EAX78278.1 - 0.026 12.4 0.0 0.031 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF2203 PF09969.9 EAX78278.1 - 0.038 14.7 0.5 0.042 14.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ERp29 PF07749.12 EAX78278.1 - 0.055 14.4 1.4 0.26 12.2 0.2 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain CENP-H PF05837.12 EAX78278.1 - 0.089 13.2 2.7 4.4 7.8 0.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NYD-SP28_assoc PF14775.6 EAX78278.1 - 0.094 12.8 4.3 1.1 9.4 1.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain PCRF PF03462.18 EAX78278.1 - 0.1 12.4 1.5 0.13 12.1 1.5 1.2 1 0 0 1 1 1 0 PCRF domain TSC22 PF01166.18 EAX78278.1 - 0.25 11.7 5.2 5.9 7.3 0.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family FapA PF03961.13 EAX78278.1 - 0.3 9.6 4.3 0.34 9.5 4.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 EAX78278.1 - 0.32 11.4 2.0 8.8 6.8 0.3 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mga PF05043.13 EAX78278.1 - 0.34 11.5 4.9 5.4 7.7 0.3 2.4 2 1 0 2 2 2 0 Mga helix-turn-helix domain Spc24 PF08286.11 EAX78278.1 - 1 9.6 7.4 8 6.8 3.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.13 EAX78278.1 - 1.2 9.2 6.8 5.4 7.2 0.4 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ZapB PF06005.12 EAX78278.1 - 2.4 8.7 9.7 7.2 7.1 3.0 2.2 1 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EAX78278.1 - 3.6 8.3 6.4 1.7 9.3 2.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF3839 PF12943.7 EAX78280.1 - 1.7e-113 378.0 8.3 1.9e-113 377.9 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78280.1 - 0.078 12.5 0.9 0.11 12.0 0.7 1.3 1 1 0 1 1 1 0 Z1 domain DNA_pol_B_2 PF03175.13 EAX78281.1 - 7e-30 104.3 7.6 1.3e-29 103.5 7.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78281.1 - 0.02 14.2 0.2 0.033 13.5 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX78281.1 - 0.041 13.9 2.1 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Pox_A32 PF04665.12 EAX78283.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78283.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78283.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78283.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78283.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78283.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX78285.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78285.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78285.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78285.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78285.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78285.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78285.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX78286.1 - 1.6e-77 260.2 12.5 2.1e-77 259.9 12.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX78286.1 - 0.06 13.6 0.8 0.15 12.3 0.1 2.0 2 1 1 3 3 3 0 Rx N-terminal domain PRD PF00874.20 EAX78286.1 - 0.068 13.5 0.5 0.74 10.2 0.0 2.6 2 1 1 3 3 3 0 PRD domain LD_cluster2 PF18163.1 EAX78286.1 - 0.13 11.7 1.0 0.91 9.0 0.0 2.4 2 1 1 3 3 3 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX78286.1 - 0.16 11.8 2.0 0.39 10.5 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX78287.1 - 3.9e-74 249.2 9.2 5.1e-74 248.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX78287.1 - 0.01 15.2 0.4 0.014 14.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 EAX78287.1 - 0.037 14.5 0.3 0.041 14.3 0.3 1.2 1 0 0 1 1 1 0 Fez1 P4Ha_N PF08336.11 EAX78287.1 - 0.037 14.0 0.5 5.6 7.0 0.2 2.3 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region THOC7 PF05615.13 EAX78287.1 - 0.041 14.1 0.6 0.066 13.5 0.2 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 LD_cluster2 PF18163.1 EAX78287.1 - 0.14 11.7 0.1 0.55 9.7 0.0 2.1 2 1 0 2 2 2 0 SLOG cluster2 BRE1 PF08647.11 EAX78287.1 - 0.23 11.5 2.7 1.4 9.0 1.1 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2939 PF11159.8 EAX78289.1 - 0.02 15.3 0.5 0.028 14.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78289.1 - 1.2 8.1 3.5 1.3 8.0 3.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein FAS_N PF17828.1 EAX78290.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX78290.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF3839 PF12943.7 EAX78291.1 - 1.5e-22 80.2 5.8 2.2e-22 79.7 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX78291.1 - 0.02 15.0 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF4106 PF13388.6 EAX78292.1 - 1.7e-240 798.4 19.1 1.7e-240 798.4 19.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX78292.1 - 1.3 7.6 6.8 0.46 9.0 2.3 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A FAS_N PF17828.1 EAX78293.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX78294.1 - 0.0085 16.5 0.2 0.0094 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) Pox_A32 PF04665.12 EAX78295.1 - 3.1e-06 26.8 2.7 3.1e-06 26.8 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78295.1 - 1.4e-05 25.4 0.2 0.00011 22.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78295.1 - 0.00014 21.9 2.8 0.00033 20.7 2.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78295.1 - 0.00061 19.6 0.1 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX78295.1 - 0.0008 19.1 0.5 0.0061 16.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78295.1 - 0.0012 18.7 0.8 0.0021 17.9 0.8 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78295.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX78295.1 - 0.09 12.2 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78295.1 - 0.14 12.6 0.1 0.76 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX78295.1 - 0.17 11.5 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF3839 PF12943.7 EAX78296.1 - 2.8e-104 347.9 7.5 3.2e-104 347.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78296.1 - 0.044 13.3 0.4 0.056 12.9 0.4 1.2 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX78296.1 - 0.4 11.3 2.8 1.4 9.6 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF4106 PF13388.6 EAX78299.1 - 1.8e-45 156.0 2.9 1.8e-45 156.0 2.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX78299.1 - 1.1 7.8 5.0 0.9 8.1 4.0 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A TcpS PF17456.2 EAX78300.1 - 0.097 12.7 3.1 13 5.8 0.3 3.0 1 1 3 4 4 4 0 Toxin-coregulated pilus protein S Glyco_hydr_116N PF12215.8 EAX78300.1 - 0.15 11.6 0.9 9 5.7 0.9 2.7 1 1 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RibD_C PF01872.17 EAX78301.1 - 1.8e-09 37.8 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF4478 PF14793.6 EAX78301.1 - 0.048 13.5 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF3839 PF12943.7 EAX78304.1 - 1.4e-94 316.1 9.2 1.7e-94 315.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX78304.1 - 0.045 14.2 0.8 1.9 9.0 0.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF3839 PF12943.7 EAX78305.1 - 9e-82 274.2 11.0 1.2e-81 273.8 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX78305.1 - 0.018 15.6 0.4 0.031 14.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX78306.1 - 6.5e-110 366.3 7.1 7.5e-110 366.1 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) UCH PF00443.29 EAX78308.1 - 4.6e-12 46.0 2.0 1.6e-10 40.9 2.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX78308.1 - 7e-06 25.9 3.3 0.00038 20.1 0.3 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX78308.1 - 0.00012 21.6 1.3 0.15 11.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_S64 PF08192.11 EAX78308.1 - 0.0019 16.8 1.1 0.027 13.0 0.0 2.0 2 0 0 2 2 2 2 Peptidase family S64 Fungal_lectin_2 PF18647.1 EAX78308.1 - 0.035 14.6 0.8 0.077 13.5 0.3 1.8 1 1 1 2 2 2 0 Alpha-galactosyl-binding fungal lectin DUF4107 PF13389.6 EAX78309.1 - 2.1e-40 138.5 3.2 2.5e-40 138.3 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78309.1 - 0.079 13.3 0.6 0.1 13.0 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DDR PF08841.10 EAX78310.1 - 0.17 10.8 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX78311.1 - 5.1e-10 38.8 3.0 2.7e-09 36.4 3.0 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX78311.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DNA_pol_B_2 PF03175.13 EAX78312.1 - 4.5e-21 75.3 3.6 8.3e-21 74.4 3.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78312.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PTR PF12789.7 EAX78314.1 - 4.8e-06 26.5 1.1 4.8e-06 26.5 1.1 3.4 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX78314.1 - 0.0062 16.2 2.9 0.093 12.3 2.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX78314.1 - 0.23 12.0 2.8 8.9 6.9 0.1 2.8 2 1 0 2 2 2 0 YmaF family DUF4106 PF13388.6 EAX78315.1 - 4.2e-231 767.4 22.1 8.3e-231 766.5 22.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX78316.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX78316.1 - 0.0049 15.8 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX78316.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX78316.1 - 0.046 13.7 0.4 0.45 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX78316.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein KilA-N PF04383.13 EAX78317.1 - 3.3e-21 75.2 0.3 8.8e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX78318.1 - 9e-109 355.6 80.5 4.3e-31 106.8 14.3 6.5 2 2 4 6 6 6 5 Phage tail repeat like DUF4116 PF13475.6 EAX78318.1 - 0.057 13.1 0.9 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX78318.1 - 0.13 12.1 4.9 1.1 9.0 1.5 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) PrpR_N PF06506.11 EAX78318.1 - 0.24 11.0 3.7 17 4.9 0.1 3.5 1 1 1 3 3 3 0 Propionate catabolism activator AviRa PF11599.8 EAX78318.1 - 0.57 9.6 9.3 1.2 8.6 0.6 3.1 1 1 2 3 3 3 0 RRNA methyltransferase AviRa GGDEF PF00990.21 EAX78319.1 - 0.094 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain FUSC PF04632.12 EAX78320.1 - 0.03 12.9 1.3 0.035 12.7 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TraF_2 PF13729.6 EAX78320.1 - 0.084 12.2 1.6 0.19 11.1 0.4 1.9 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF1664 PF07889.12 EAX78320.1 - 0.17 12.0 1.5 2.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAX78320.1 - 0.18 12.0 1.5 0.3 11.3 0.9 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A32 PF04665.12 EAX78321.1 - 5.1e-07 29.4 2.3 7.2e-07 28.9 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78321.1 - 0.0051 16.5 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78321.1 - 0.055 13.2 0.2 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX78321.1 - 0.059 12.9 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX78321.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78321.1 - 0.18 11.8 2.0 1.5 8.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78322.1 - 1e-158 526.1 13.1 1.3e-158 525.8 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX78322.1 - 0.044 14.0 0.1 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF29 MitMem_reg PF13012.6 EAX78322.1 - 0.097 13.1 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78322.1 - 1.5 9.3 7.5 2.6 8.6 0.9 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX78323.1 - 4e-34 118.1 2.2 5.8e-34 117.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX78325.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX78326.1 - 0.072 13.7 5.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX78328.1 - 1e-29 102.6 1.6 1.4e-29 102.2 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX78328.1 - 0.031 14.5 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX78329.1 - 7.4e-80 267.9 11.7 9.7e-80 267.5 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78329.1 - 0.069 12.7 0.6 0.27 10.7 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX78330.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78330.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78330.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78330.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78331.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX78332.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DOCK-C2 PF14429.6 EAX78333.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins DUF4107 PF13389.6 EAX78337.1 - 2.2e-35 122.2 1.9 3.1e-35 121.7 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX78338.1 - 0.022 15.2 0.6 0.05 14.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX78339.1 - 5.6e-80 268.3 10.3 7.5e-80 267.9 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX78339.1 - 0.05 12.8 0.1 0.071 12.3 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II NTP_transf_6 PF06042.11 EAX78339.1 - 0.1 12.5 1.0 0.29 11.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX78340.1 - 1e-42 144.5 0.4 2.4e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78340.1 - 0.0037 17.8 0.1 0.014 16.0 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family ABC1 PF03109.16 EAX78340.1 - 0.069 13.3 0.3 2.3 8.4 0.0 2.7 1 1 1 2 2 2 0 ABC1 family DUF3213 PF11491.8 EAX78341.1 - 0.032 14.4 0.4 0.074 13.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KIP1 PF07765.12 EAX78341.1 - 2.1 8.6 6.9 13 6.0 0.3 2.4 1 1 1 2 2 2 0 KIP1-like protein Pox_A32 PF04665.12 EAX78342.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78342.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78342.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78342.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) SPATA3 PF15662.5 EAX78343.1 - 2.8 8.5 6.0 3.5 8.2 6.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family ANAPC4_WD40 PF12894.7 EAX78345.1 - 0.017 15.4 0.0 0.21 11.9 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX78345.1 - 0.072 14.0 0.1 0.4 11.6 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Pox_D5 PF03288.16 EAX78347.1 - 4.8e-05 23.8 2.2 0.00033 21.1 2.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like GGDEF PF00990.21 EAX78348.1 - 0.065 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX78349.1 - 2.8e-55 186.2 6.4 3.3e-55 186.0 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX78350.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78350.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX78351.1 - 0.22 11.5 7.2 0.24 11.4 7.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX78352.1 - 1.6e-05 24.5 3.7 3.1e-05 23.5 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX78352.1 - 0.0093 16.0 1.2 0.016 15.2 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX78352.1 - 0.017 14.7 0.4 0.034 13.7 0.4 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX78352.1 - 0.047 14.0 1.6 0.12 12.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX78352.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF2897 PF11446.8 EAX78353.1 - 0.33 10.9 2.3 0.7 9.8 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX78354.1 - 7.4e-58 194.5 4.4 8.3e-58 194.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX78355.1 - 0.0002 21.8 2.0 0.0013 19.2 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX78355.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX78355.1 - 0.041 14.5 0.1 0.085 13.5 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain SR-25 PF10500.9 EAX78356.1 - 0.046 13.3 27.9 0.055 13.1 27.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4887 PF16228.5 EAX78356.1 - 0.26 11.5 37.9 0.3 11.3 37.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DUF4551 PF15087.6 EAX78356.1 - 1.5 7.5 14.2 1.6 7.5 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RRN3 PF05327.11 EAX78356.1 - 4.7 5.6 11.5 6 5.3 11.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_UL25 PF01499.16 EAX78356.1 - 5 5.5 8.7 6.2 5.2 8.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family MID_MedPIWI PF18296.1 EAX78356.1 - 6 6.6 13.2 7 6.4 13.2 1.0 1 0 0 1 1 1 0 MID domain of medPIWI SWIRM-assoc_2 PF16496.5 EAX78356.1 - 9.6 5.0 24.6 11 4.8 24.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Porin_4 PF13609.6 EAX78357.1 - 7.9e-05 22.6 0.5 8.7e-05 22.4 0.5 1.0 1 0 0 1 1 1 1 Gram-negative porin MULE PF10551.9 EAX78358.1 - 3.6e-10 40.1 0.3 6.6e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF1878 PF08963.10 EAX78358.1 - 0.2 12.2 1.3 2.2 8.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) DUF3839 PF12943.7 EAX78359.1 - 1.7e-25 89.9 3.9 2.6e-25 89.3 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX78359.1 - 0.045 12.9 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX78359.1 - 0.058 13.8 0.2 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PapD_N PF00345.20 EAX78361.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX78363.1 - 6.1e-07 29.1 2.6 6.1e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78363.1 - 4.4e-05 23.3 0.3 0.41 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78363.1 - 8.1e-05 22.9 0.2 0.00053 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78363.1 - 0.00011 22.3 3.1 0.00024 21.2 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78363.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78363.1 - 0.0021 17.9 0.5 0.0042 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78363.1 - 0.0024 17.6 0.5 0.013 15.1 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78363.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX78363.1 - 0.06 12.8 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX78363.1 - 0.073 12.6 0.1 0.23 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX78363.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX78363.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78363.1 - 0.13 12.7 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78363.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX78364.1 - 1.2e-13 50.9 0.1 2.3e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX78364.1 - 0.045 13.7 1.1 0.19 11.7 0.0 2.4 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX78364.1 - 0.61 9.5 1.5 1.1 8.6 0.9 1.7 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX78365.1 - 1.2e-157 522.6 11.5 1.4e-157 522.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78365.1 - 1.8 9.1 6.9 1.8 9.1 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX78366.1 - 8.7e-264 875.1 19.9 1.3e-263 874.6 19.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78366.1 - 0.017 15.4 0.1 0.87 9.9 0.2 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated PapD_N PF00345.20 EAX78368.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX78368.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX78369.1 - 1.1e-111 372.1 6.7 1.3e-111 371.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78369.1 - 0.087 12.3 0.5 0.13 11.7 0.4 1.3 1 1 0 1 1 1 0 Z1 domain DUF1493 PF07377.12 EAX78370.1 - 0.011 16.2 0.7 0.021 15.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX78371.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX78372.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX78375.1 - 2.3e-33 114.4 0.6 5.6e-33 113.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX78375.1 - 0.086 12.8 0.7 0.18 11.8 0.7 1.6 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon KilA-N PF04383.13 EAX78376.1 - 2.4e-35 120.8 1.3 3.3e-35 120.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78376.1 - 0.0049 17.5 0.1 0.013 16.1 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX78376.1 - 0.73 9.9 4.1 2.3 8.2 0.5 2.3 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX78377.1 - 5.4e-07 30.1 0.4 1.1e-06 29.2 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX78377.1 - 0.16 12.7 0.4 0.44 11.2 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 C2 PF00168.30 EAX78379.1 - 7.5e-64 212.5 1.1 7.5e-23 80.8 0.2 3.2 3 0 0 3 3 3 3 C2 domain DOCK-C2 PF14429.6 EAX78379.1 - 0.00018 21.4 0.1 5 6.9 0.0 3.9 4 0 0 4 4 4 2 C2 domain in Dock180 and Zizimin proteins VID27_PH PF17747.1 EAX78379.1 - 0.014 15.6 0.8 47 4.3 0.0 3.6 4 0 0 4 4 4 0 VID27 PH-like domain B9-C2 PF07162.11 EAX78379.1 - 0.033 14.4 0.0 5.8 7.1 0.0 3.2 3 1 1 4 4 4 0 Ciliary basal body-associated, B9 protein DNA_pol_B_2 PF03175.13 EAX78380.1 - 1.9e-37 129.3 16.0 9.5e-37 126.9 16.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX78382.1 - 3.8e-158 524.2 12.7 4.4e-158 524.0 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78382.1 - 0.097 13.1 0.3 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78382.1 - 0.55 10.7 7.2 1.8 9.1 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX78383.1 - 1.1e-05 26.0 0.1 2.5e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78383.1 - 0.014 15.2 0.2 0.081 12.8 0.1 2.3 2 1 0 2 2 2 0 KilA-N domain FAS_N PF17828.1 EAX78384.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX78384.1 - 0.12 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF2939 PF11159.8 EAX78385.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF1043 PF06295.12 EAX78386.1 - 0.043 13.8 0.2 0.056 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX78388.1 - 1.7e-29 101.9 1.0 2.4e-29 101.5 0.2 1.7 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX78388.1 - 1.1 9.3 4.6 2.4 8.2 0.6 2.3 2 1 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX78389.1 - 6.7e-07 29.8 0.5 2.2e-06 28.1 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX78389.1 - 0.11 12.3 1.1 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX78389.1 - 0.16 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain PTR PF12789.7 EAX78392.1 - 4.1e-10 39.6 9.3 1.1e-08 35.1 5.6 4.2 5 0 0 5 5 5 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX78392.1 - 0.074 13.2 0.1 8.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain EpuA PF11772.8 EAX78392.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pirin PF02678.16 EAX78392.1 - 0.12 12.4 0.4 0.62 10.1 0.0 2.3 3 0 0 3 3 3 0 Pirin IL2 PF00715.17 EAX78392.1 - 0.27 11.2 3.3 7.6 6.5 0.1 2.8 2 1 1 3 3 3 0 Interleukin 2 EMP24_GP25L PF01105.24 EAX78392.1 - 2.5 8.0 4.8 36 4.2 1.0 3.1 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF5082 PF16888.5 EAX78392.1 - 8.2 6.7 8.6 20 5.5 4.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) GGDEF PF00990.21 EAX78393.1 - 0.057 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX78394.1 - 8e-62 207.4 6.4 8.9e-62 207.2 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) FliJ PF02050.16 EAX78395.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX78396.1 - 1.1e-71 240.2 4.0 1.4e-71 239.9 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDE_Tnp_4 PF13359.6 EAX78397.1 - 9.1e-37 126.2 0.0 1.2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX78397.1 - 7.5e-08 32.3 0.7 2.3e-06 27.4 0.7 2.2 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 EAX78397.1 - 0.039 14.3 0.1 0.095 13.1 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain DUF3839 PF12943.7 EAX78398.1 - 1e-07 31.7 1.4 1e-07 31.7 1.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78398.1 - 0.045 14.1 0.1 0.065 13.5 0.1 1.4 1 0 0 1 1 1 0 PRD domain PTR PF12789.7 EAX78400.1 - 1.1e-51 172.7 36.4 5.4e-34 116.0 16.1 5.4 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX78400.1 - 0.16 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4106 PF13388.6 EAX78401.1 - 1.9e-275 913.6 35.7 2.5e-273 906.5 35.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78401.1 - 0.022 15.0 0.1 1 9.7 0.2 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated Meiosis_expr PF15163.6 EAX78402.1 - 0.089 13.5 1.2 0.13 13.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX78402.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX78404.1 - 9.2e-158 523.0 12.6 1.1e-157 522.7 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78404.1 - 0.078 13.4 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78404.1 - 0.16 12.5 7.1 2 8.9 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX78404.1 - 0.86 9.9 5.1 13 6.1 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal Pox_A32 PF04665.12 EAX78405.1 - 4.7e-07 29.5 2.6 4.7e-07 29.5 2.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78405.1 - 3.7e-05 23.5 0.2 0.38 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78405.1 - 3.8e-05 24.0 0.2 0.00028 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78405.1 - 0.00025 21.1 3.8 0.00047 20.2 3.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78405.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78405.1 - 0.002 17.9 1.3 0.003 17.4 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78405.1 - 0.0038 16.9 2.7 0.01 15.5 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78405.1 - 0.013 15.8 0.0 0.032 14.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain TPK_catalytic PF04263.16 EAX78405.1 - 0.082 13.0 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX78405.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78405.1 - 0.1 13.0 0.1 0.89 10.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78405.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78405.1 - 0.45 10.8 4.0 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX78405.1 - 0.69 10.6 11.5 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Pox_A32 PF04665.12 EAX78408.1 - 5.8e-07 29.2 2.2 5.8e-07 29.2 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78408.1 - 5.4e-05 23.0 0.2 0.39 10.4 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78408.1 - 6.1e-05 23.3 0.2 0.00043 20.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78408.1 - 7.9e-05 22.7 2.7 0.00016 21.7 2.7 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78408.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX78408.1 - 0.0018 18.0 0.4 0.0092 15.6 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78408.1 - 0.0019 18.0 0.3 0.004 17.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78408.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX78408.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX78408.1 - 0.076 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX78408.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX78408.1 - 0.1 13.0 1.9 0.73 10.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2805) AAA PF00004.29 EAX78408.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78408.1 - 0.44 10.8 3.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX78408.1 - 0.87 10.0 4.8 0.33 11.4 1.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX78410.1 - 2.1e-156 518.5 14.1 2.5e-156 518.3 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78410.1 - 0.094 13.2 1.5 0.58 10.6 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX78410.1 - 0.32 11.5 6.7 1.9 9.0 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX78410.1 - 1.6 9.3 4.8 2.5 8.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX78411.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX78412.1 - 7e-55 184.9 7.9 7.8e-55 184.7 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78412.1 - 0.089 13.0 0.1 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3464 PF11947.8 EAX78413.1 - 1.3 8.8 3.0 0.99 9.1 1.8 1.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 AAA_22 PF13401.6 EAX78414.1 - 2.4e-05 24.6 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78414.1 - 2.4e-05 24.1 0.3 0.26 11.0 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX78414.1 - 4.2e-05 23.1 1.9 4.2e-05 23.1 1.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX78414.1 - 0.00015 21.8 3.6 0.00031 20.8 3.6 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78414.1 - 0.00044 20.1 0.1 0.00081 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX78414.1 - 0.0014 18.3 0.4 0.011 15.4 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78414.1 - 0.0015 18.4 0.9 0.0041 16.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78414.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX78414.1 - 0.049 13.2 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78414.1 - 0.062 13.7 0.1 0.55 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX78414.1 - 0.063 12.8 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX78414.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78414.1 - 0.38 11.0 4.6 8.4 6.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Ank_2 PF12796.7 EAX78415.1 - 7.9e-36 122.5 9.7 2e-13 50.7 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX78415.1 - 2.7e-32 110.7 5.1 4.8e-10 39.8 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX78415.1 - 6.4e-29 99.6 0.7 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX78415.1 - 5.1e-25 84.8 2.3 0.00021 21.5 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX78415.1 - 9.6e-21 73.3 4.1 0.0052 17.2 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX78415.1 - 0.0017 18.3 1.0 1.5 8.9 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) DUF4108 PF13390.6 EAX78416.1 - 4.2e-64 214.8 6.4 4.7e-64 214.6 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78416.1 - 0.1 12.8 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide ResIII PF04851.15 EAX78418.1 - 2.3e-05 24.5 0.4 3.1e-05 24.0 0.4 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78418.1 - 0.00032 20.5 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX78418.1 - 0.00052 20.3 0.0 0.00079 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX78418.1 - 0.0022 17.9 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78418.1 - 0.0078 16.6 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX78418.1 - 0.038 13.4 0.0 0.071 12.6 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX78418.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX78418.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX78418.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX78419.1 - 7e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX78419.1 - 0.04 13.9 0.6 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin KilA-N PF04383.13 EAX78422.1 - 9.3e-32 109.2 0.1 1.8e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX78422.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KilA-N PF04383.13 EAX78424.1 - 5.8e-25 87.3 0.2 1.6e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF2362 PF10154.9 EAX78425.1 - 0.0018 17.3 3.9 0.0025 16.9 3.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) LBP_C PF17386.2 EAX78425.1 - 0.4 10.6 5.0 47 4.0 0.0 3.7 4 0 0 4 4 4 0 Lacto-N-biose phosphorylase C-terminal domain AMPKBI PF04739.15 EAX78425.1 - 1.2 9.4 22.6 8.2 6.8 0.6 4.1 1 1 2 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain Pox_D5 PF03288.16 EAX78426.1 - 3.8e-06 27.3 2.3 2.9e-05 24.4 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78426.1 - 0.029 15.0 0.1 0.057 14.1 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78426.1 - 0.083 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX78427.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78428.1 - 0.31 11.0 3.2 0.65 9.9 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX78429.1 - 2.8e-156 518.1 13.7 3.3e-156 517.9 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78429.1 - 0.11 12.0 0.1 0.57 9.7 0.0 1.8 1 1 1 2 2 2 0 SLOG cluster2 MitMem_reg PF13012.6 EAX78429.1 - 0.14 12.5 0.7 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX78429.1 - 0.26 11.1 1.9 0.76 9.6 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78429.1 - 1.2 9.6 6.2 7.3 7.1 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX78430.1 - 4.3e-28 98.4 6.7 5.8e-28 98.0 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX78430.1 - 0.05 12.8 0.1 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX78430.1 - 0.11 13.0 0.2 0.21 12.1 0.1 1.6 2 0 0 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EAX78431.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX78431.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX78431.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PapD_N PF00345.20 EAX78433.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX78434.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX78434.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KRAB PF01352.27 EAX78435.1 - 1.9e-07 30.6 9.2 27 4.5 0.0 7.5 7 0 0 7 7 7 0 KRAB box UPF0223 PF05256.12 EAX78435.1 - 4.6e-07 30.1 32.7 1.3 9.4 0.6 6.5 1 1 5 6 6 6 6 Uncharacterised protein family (UPF0223) DUF3644 PF12358.8 EAX78435.1 - 0.00025 21.4 12.1 10 6.7 0.8 5.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3644) TetR_C_35 PF18556.1 EAX78435.1 - 0.00038 20.5 0.3 18 5.5 0.0 3.0 1 1 2 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain SpecificRecomb PF10136.9 EAX78435.1 - 0.00068 18.1 5.9 0.035 12.4 1.2 1.9 1 1 1 2 2 2 2 Site-specific recombinase CCDC117 PF15810.5 EAX78435.1 - 0.0012 19.2 11.9 1 9.7 1.9 3.3 1 1 2 3 3 3 3 Coiled-coil domain-containing protein 117 DUF2358 PF10184.9 EAX78435.1 - 0.0015 18.8 12.7 58 4.0 0.1 6.2 1 1 6 7 7 7 0 Uncharacterized conserved protein (DUF2358) PAS_2 PF08446.11 EAX78435.1 - 0.0065 17.1 10.2 6.3 7.5 1.7 3.9 1 1 3 4 4 4 2 PAS fold DUF2787 PF10980.8 EAX78435.1 - 0.016 15.4 7.1 8 6.7 0.5 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2787) Lipoprotein_16 PF03923.13 EAX78435.1 - 0.026 14.2 19.0 0.72 9.5 3.1 3.0 1 1 2 3 3 3 0 Uncharacterized lipoprotein DUF445 PF04286.12 EAX78435.1 - 0.034 14.0 16.1 0.05 13.4 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Endopep_inhib PF16800.5 EAX78435.1 - 0.043 13.7 24.0 8.4 6.3 0.5 5.7 1 1 5 6 6 6 0 IseA DL-endopeptidase inhibitor UvrB PF12344.8 EAX78435.1 - 0.052 13.4 8.3 81 3.2 0.0 5.4 1 1 5 6 6 6 0 Ultra-violet resistance protein B CARD_2 PF16739.5 EAX78435.1 - 0.23 11.4 3.5 54 3.9 0.1 3.0 1 1 2 3 3 3 0 Caspase recruitment domain DUF234 PF03008.14 EAX78435.1 - 0.27 11.7 10.1 19 5.8 0.4 3.3 1 1 4 5 5 5 0 Archaea bacterial proteins of unknown function CEP19 PF14933.6 EAX78435.1 - 0.38 11.0 18.0 1.5 9.1 7.7 2.2 1 1 1 2 2 2 0 CEP19-like protein Flavodoxin_2 PF02525.17 EAX78435.1 - 0.39 10.4 3.0 22 4.7 3.0 2.6 1 1 0 1 1 1 0 Flavodoxin-like fold Rhabdo_NV PF02484.15 EAX78435.1 - 1.9 8.7 5.7 96 3.2 0.2 3.2 1 1 5 6 6 6 0 Rhabdovirus Non-virion protein P5-ATPase PF12409.8 EAX78435.1 - 2.7 8.1 19.2 21 5.2 1.0 4.1 1 1 2 3 3 3 0 P5-type ATPase cation transporter DnaI_N PF07319.11 EAX78435.1 - 3.4 8.4 20.7 12 6.7 2.0 3.1 1 1 3 4 4 4 0 Primosomal protein DnaI N-terminus Chalcone_3 PF16036.5 EAX78435.1 - 7.6 6.6 12.8 16 5.5 2.9 2.3 1 1 0 2 2 2 0 Chalcone isomerase-like DUF5371 PF17341.2 EAX78435.1 - 9.8 6.5 16.3 2.1e+02 2.2 0.1 5.9 6 1 0 6 6 6 0 Family of unknown function (DUF5371) PapD_N PF00345.20 EAX78437.1 - 0.033 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain UCH PF00443.29 EAX78439.1 - 2.4e-10 40.3 0.4 3.9e-10 39.7 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX78439.1 - 0.00062 19.5 1.3 0.0011 18.7 1.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3839 PF12943.7 EAX78440.1 - 5.7e-152 504.0 12.2 7e-152 503.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78440.1 - 0.0096 16.4 7.2 0.059 13.8 0.4 3.4 2 2 1 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX78440.1 - 0.037 14.5 1.3 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX78440.1 - 0.27 11.8 5.9 0.29 11.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX78440.1 - 0.27 11.6 1.4 1.1 9.7 0.5 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2897 PF11446.8 EAX78442.1 - 0.078 12.9 3.1 0.14 12.0 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX78443.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX78445.1 - 1e-158 526.1 14.3 1.3e-158 525.8 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78445.1 - 0.063 13.7 1.9 0.14 12.5 0.4 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX78445.1 - 0.12 12.6 0.5 3.8 7.9 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain LD_cluster2 PF18163.1 EAX78445.1 - 0.15 11.6 0.6 0.4 10.2 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 KELK PF15796.5 EAX78445.1 - 0.53 10.8 6.7 2 8.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX78445.1 - 0.89 9.9 5.1 12 6.2 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal DUF3839 PF12943.7 EAX78447.1 - 5.7e-157 520.4 12.7 7.1e-157 520.1 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78447.1 - 0.12 12.8 0.3 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78447.1 - 0.28 11.6 7.3 2.3 8.8 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX78448.1 - 4.5e-11 42.6 0.0 9.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain NAD_Gly3P_dh_N PF01210.23 EAX78449.1 - 3.2e-40 137.7 0.0 5.5e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EAX78449.1 - 2e-36 125.4 0.3 4.5e-36 124.2 0.3 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EAX78449.1 - 0.016 15.8 0.5 0.27 11.9 0.1 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3839 PF12943.7 EAX78450.1 - 2.4e-81 272.8 10.8 3.1e-81 272.4 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX78450.1 - 0.074 13.6 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CREPT PF16566.5 EAX78451.1 - 0.029 14.6 0.2 0.07 13.3 0.2 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX78451.1 - 0.91 9.7 6.0 0.33 11.1 1.6 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3839 PF12943.7 EAX78452.1 - 4.2e-07 29.7 1.4 7.7e-07 28.8 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_D5 PF03288.16 EAX78454.1 - 2.2e-05 24.8 2.3 0.00011 22.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78454.1 - 0.057 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX78455.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78456.1 - 3.3 7.7 6.8 1.4 8.9 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX78457.1 - 1.7e-31 108.1 9.6 1.7e-31 108.1 9.6 2.3 2 0 0 2 2 2 1 Phage tail repeat like DUF4795 PF16043.5 EAX78457.1 - 0.66 9.5 4.9 6.8 6.2 4.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX78458.1 - 4.4e-12 45.6 2.6 7.7e-12 44.8 2.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PSP PF04046.16 EAX78460.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX78461.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat ABC2_membrane_3 PF12698.7 EAX78463.1 - 0.048 12.8 0.4 0.049 12.7 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DNA_pol_B_2 PF03175.13 EAX78464.1 - 5.9e-20 71.6 4.2 1.2e-19 70.6 4.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78464.1 - 0.027 13.8 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Col_cuticle_N PF01484.17 EAX78464.1 - 0.12 12.5 0.4 0.38 10.8 0.4 1.8 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain TPR_MLP1_2 PF07926.12 EAX78465.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX78465.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX78465.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Ketoacyl-synt_C PF02801.22 EAX78466.1 - 0.073 13.1 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Pox_A32 PF04665.12 EAX78467.1 - 7.1e-08 32.2 1.1 8.6e-08 31.9 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78467.1 - 0.0041 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78467.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78467.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) YvrJ PF12841.7 EAX78470.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family PTR PF12789.7 EAX78471.1 - 2.9e-25 88.1 40.8 2.3e-09 37.2 5.7 5.1 5 0 0 5 5 5 3 Phage tail repeat like EMP24_GP25L PF01105.24 EAX78471.1 - 0.053 13.5 11.2 1.6 8.6 1.2 3.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD PH_TFIIH PF08567.11 EAX78471.1 - 0.34 11.2 3.2 82 3.6 0.1 3.4 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain RraB PF06877.11 EAX78471.1 - 0.43 11.3 7.4 24 5.7 0.2 3.5 2 1 1 3 3 3 0 Regulator of ribonuclease activity B Ferritin PF00210.24 EAX78471.1 - 0.47 10.4 7.4 6.3 6.7 0.3 2.6 2 0 0 2 2 2 0 Ferritin-like domain DUF1722 PF08349.11 EAX78471.1 - 0.61 10.4 4.4 2.2 8.6 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PA28_alpha PF02251.18 EAX78471.1 - 0.65 10.1 6.9 10 6.3 0.3 3.2 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit SesA PF17107.5 EAX78471.1 - 1.8 8.8 6.4 5.9 7.1 0.6 2.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF5082 PF16888.5 EAX78471.1 - 4 7.7 21.0 2.1 8.6 10.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) RecG_N PF17190.4 EAX78471.1 - 7.5 7.4 14.4 2 9.2 0.6 3.9 3 1 0 4 4 4 0 RecG N-terminal helical domain L27 PF02828.16 EAX78471.1 - 9.7 6.0 6.4 15 5.4 0.4 3.7 3 2 1 4 4 4 0 L27 domain Pox_A32 PF04665.12 EAX78472.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78472.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78472.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78472.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX78473.1 - 3.8e-07 29.8 2.1 5.7e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78473.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78473.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78473.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78473.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX78473.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX78473.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78473.1 - 0.59 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX78474.1 - 1.1e-06 29.1 0.3 2.2e-06 28.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX78475.1 - 4.5e-37 125.9 27.3 8.3e-32 109.0 17.1 3.2 3 1 1 4 4 4 2 Phage tail repeat like AviRa PF11599.8 EAX78475.1 - 0.17 11.3 0.6 0.36 10.3 0.6 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF3839 PF12943.7 EAX78476.1 - 2.1e-150 498.9 13.9 2.6e-150 498.6 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX78476.1 - 0.015 15.6 0.6 1.4 9.3 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX78476.1 - 0.18 11.6 2.1 0.4 10.5 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF5398 PF17376.2 EAX78476.1 - 0.33 11.6 3.4 1 10.0 0.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX78476.1 - 0.35 11.4 4.8 4.2 7.9 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4795 PF16043.5 EAX78478.1 - 0.0051 16.4 5.6 0.11 12.1 6.5 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX78479.1 - 4.6e-94 314.4 7.8 5.2e-94 314.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX78480.1 - 1e-121 405.0 8.3 1.2e-121 404.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78480.1 - 0.093 13.2 1.5 0.94 10.0 0.2 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2547 PF10818.8 EAX78480.1 - 0.14 13.1 0.6 5 8.1 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Trypan_PARP PF05887.11 EAX78483.1 - 0.049 13.6 9.0 0.065 13.2 9.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MATalpha_HMGbox PF04769.12 EAX78485.1 - 0.14 11.4 0.0 2.3 7.5 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box Amidase02_C PF12123.8 EAX78486.1 - 0.006 16.3 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78486.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX78487.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein zf-C2H2_assoc2 PF16624.5 EAX78488.1 - 0.0029 18.6 1.1 0.0032 18.4 1.1 1.1 1 0 0 1 1 1 1 Unstructured region upstream of a zinc-finger NEMP PF10225.9 EAX78488.1 - 0.53 9.9 1.2 0.57 9.8 1.2 1.0 1 0 0 1 1 1 0 NEMP family DUF4106 PF13388.6 EAX78489.1 - 8.8e-270 894.9 38.6 6.9e-268 888.6 38.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78489.1 - 0.00099 19.4 0.1 0.049 13.9 0.2 2.7 2 0 0 2 2 2 1 Kidney androgen-regulated Mid2 PF04478.12 EAX78490.1 - 0.00021 21.1 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAX78490.1 - 0.0038 17.2 0.1 0.0046 16.9 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EAX78490.1 - 0.005 17.1 0.3 0.0075 16.5 0.2 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 EAX78490.1 - 0.026 12.9 0.0 0.028 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Rhabdo_glycop PF00974.18 EAX78490.1 - 0.087 11.3 0.0 0.092 11.2 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.6 EAX78490.1 - 0.1 13.5 1.2 0.12 13.3 0.4 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR19-TM PF15176.6 EAX78490.1 - 0.12 12.4 0.8 0.16 12.0 0.6 1.3 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain UL45 PF05473.12 EAX78490.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like FGFR3_TM PF18123.1 EAX78490.1 - 0.26 10.9 6.1 0.38 10.3 6.1 1.2 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain PRIMA1 PF16101.5 EAX78490.1 - 0.92 9.6 5.9 1.9 8.6 5.9 1.5 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Synaptobrevin PF00957.21 EAX78490.1 - 2.8 7.8 5.6 4 7.3 5.6 1.2 1 0 0 1 1 1 0 Synaptobrevin Insulin_TMD PF17870.1 EAX78490.1 - 4.6 7.4 7.5 4 7.6 4.7 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4108 PF13390.6 EAX78491.1 - 1.2e-62 210.1 6.1 1.3e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78492.1 - 1.9 8.4 3.7 3.9 7.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GGDEF PF00990.21 EAX78493.1 - 0.042 13.6 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3417 PF11897.8 EAX78493.1 - 0.1 13.0 0.3 0.12 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Ly49 PF08391.10 EAX78493.1 - 0.21 12.0 1.4 0.25 11.7 1.4 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX78493.1 - 0.45 10.4 3.8 0.93 9.4 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX78496.1 - 9.3e-06 26.1 0.2 2.1e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain ARA70 PF12489.8 EAX78497.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3839 PF12943.7 EAX78498.1 - 1e-155 516.3 12.6 1.2e-155 516.0 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78498.1 - 0.015 15.8 1.5 0.099 13.1 0.2 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX78498.1 - 0.15 11.9 1.7 0.39 10.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78498.1 - 0.55 10.7 7.2 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78499.1 - 2.3e-07 30.6 0.9 2.7e-07 30.3 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX78499.1 - 0.0064 15.4 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX78499.1 - 0.0085 15.7 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78499.1 - 0.016 14.9 0.1 0.035 13.8 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78499.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) RNA_helicase PF00910.22 EAX78499.1 - 0.1 13.0 0.1 0.24 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DUF2939 PF11159.8 EAX78500.1 - 0.063 13.7 0.4 0.085 13.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78500.1 - 1.2 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX78500.1 - 1.5 8.8 5.5 1.6 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Gly-zipper_Omp PF13488.6 EAX78503.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX78503.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX78503.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DDE_Tnp_4 PF13359.6 EAX78504.1 - 2.9e-12 46.5 0.0 5.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX78504.1 - 2.3e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX78504.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Pox_A32 PF04665.12 EAX78506.1 - 2.3e-07 30.5 1.0 1.3e-06 28.1 0.0 2.3 1 1 2 3 3 3 1 Poxvirus A32 protein Zot PF05707.12 EAX78506.1 - 0.062 12.9 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 EAX78506.1 - 0.21 11.8 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2897 PF11446.8 EAX78507.1 - 0.25 11.2 3.6 0.47 10.4 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX78507.1 - 0.29 11.5 2.6 0.33 11.3 2.6 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4108 PF13390.6 EAX78508.1 - 1.4e-62 209.8 5.9 1.6e-62 209.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX78509.1 - 1.1e-34 118.7 0.7 2.1e-34 117.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX78510.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78510.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78510.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78510.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78511.1 - 4e-80 268.8 11.1 5.3e-80 268.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78511.1 - 0.081 12.4 0.8 0.3 10.6 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX78511.1 - 0.1 13.2 0.7 0.16 12.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX78512.1 - 3.8e-07 29.8 0.3 4.6e-07 29.6 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX78512.1 - 0.0044 15.9 0.0 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF3783 PF12646.7 EAX78512.1 - 0.043 13.8 0.4 0.41 10.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX78512.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Zot PF05707.12 EAX78512.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3839 PF12943.7 EAX78513.1 - 3.2e-73 246.1 8.0 4.3e-73 245.7 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4106 PF13388.6 EAX78514.1 - 1.8e-274 910.3 21.7 1.8e-274 910.3 21.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX78514.1 - 0.49 10.0 3.0 0.49 9.9 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) FapA PF03961.13 EAX78514.1 - 1.7 7.2 9.5 0.31 9.6 3.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Pox_A32 PF04665.12 EAX78519.1 - 3e-05 23.6 3.2 3.3e-05 23.5 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX78519.1 - 0.0032 17.5 1.1 0.007 16.4 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX78519.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX78519.1 - 0.06 13.6 2.0 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX78520.1 - 7.9e-151 500.3 14.6 9.6e-151 500.0 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78520.1 - 0.1 13.1 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78520.1 - 0.58 10.6 7.0 1.9 9.0 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78521.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78521.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78521.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78521.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX78523.1 - 3e-54 182.9 4.2 3.5e-54 182.6 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2939 PF11159.8 EAX78524.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78524.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX78524.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX78524.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX78525.1 - 0.023 14.7 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX78527.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX78527.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX78527.1 - 0.24 10.8 0.6 1.1 8.6 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain T5orf172 PF10544.9 EAX78528.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78529.1 - 2.2e-35 120.9 0.8 3.8e-35 120.1 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78529.1 - 0.0043 17.7 0.1 0.011 16.4 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family KilA-N PF04383.13 EAX78530.1 - 2.2e-21 75.8 0.5 5.4e-21 74.5 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain YvrJ PF12841.7 EAX78531.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family FliD_N PF02465.18 EAX78532.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX78532.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ZapB PF06005.12 EAX78533.1 - 0.00094 19.6 0.5 0.4 11.2 0.1 2.2 2 0 0 2 2 2 2 Cell division protein ZapB GIT_CC PF16559.5 EAX78533.1 - 0.0049 16.7 0.8 0.95 9.4 0.0 3.1 2 1 1 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor LURAP PF14854.6 EAX78533.1 - 0.018 15.0 0.5 0.87 9.6 0.0 2.3 1 1 1 2 2 2 0 Leucine rich adaptor protein DivIC PF04977.15 EAX78533.1 - 0.058 13.2 0.6 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF1493 PF07377.12 EAX78534.1 - 0.092 13.2 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1493 PF07377.12 EAX78537.1 - 0.018 15.5 0.6 0.031 14.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX78538.1 - 1.7e-118 394.4 8.8 2e-118 394.2 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78538.1 - 0.34 11.4 1.9 1.1 9.8 0.7 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78539.1 - 3.8e-07 29.8 2.1 5.7e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78539.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78539.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78539.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78539.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX78539.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX78539.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78539.1 - 0.59 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PadR PF03551.14 EAX78540.1 - 0.007 16.3 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX78541.1 - 1.3e-08 34.2 1.2 2.4e-08 33.3 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3781 PF12636.7 EAX78544.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX78545.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX78547.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78547.1 - 0.18 11.7 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX78548.1 - 9.7e-41 139.6 3.6 1.1e-40 139.4 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78548.1 - 0.049 14.0 0.1 0.083 13.3 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX78549.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX78552.1 - 8.2e-07 28.7 3.0 8.2e-07 28.7 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78552.1 - 5.6e-05 23.0 0.2 0.34 10.6 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX78552.1 - 6.1e-05 23.3 0.2 0.0004 20.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78552.1 - 9.6e-05 22.5 3.0 0.00021 21.3 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78552.1 - 0.00063 19.6 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78552.1 - 0.0019 18.0 0.4 0.0033 17.3 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78552.1 - 0.0024 17.5 0.4 0.017 14.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78552.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX78552.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX78552.1 - 0.075 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX78552.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78552.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78552.1 - 0.45 10.8 3.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX78552.1 - 0.85 10.1 4.8 0.33 11.4 1.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3781 PF12636.7 EAX78554.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4106 PF13388.6 EAX78555.1 - 1.1e-265 881.3 23.0 1.1e-265 881.3 23.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78555.1 - 0.019 15.3 0.2 0.86 9.9 0.2 2.7 2 1 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX78555.1 - 0.026 14.4 0.2 0.077 12.8 0.2 1.8 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) VP4_2 PF08935.10 EAX78555.1 - 0.15 12.7 0.6 0.32 11.6 0.6 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit DUF3839 PF12943.7 EAX78556.1 - 3.8e-50 170.6 3.2 4.3e-50 170.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78556.1 - 0.086 12.3 0.1 0.092 12.2 0.1 1.0 1 0 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX78557.1 - 1.2e-41 141.1 0.5 1.2e-41 141.1 0.5 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78557.1 - 0.015 15.9 0.1 0.057 14.0 0.0 2.0 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX78558.1 - 5.2e-07 30.2 0.3 1e-06 29.2 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain PapD_N PF00345.20 EAX78560.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Transposase_mut PF00872.18 EAX78561.1 - 0.0015 17.5 0.2 0.0017 17.3 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX78561.1 - 0.014 15.3 0.4 0.018 15.0 0.4 1.1 1 0 0 1 1 1 0 Vta1 like DDE_Tnp_ISL3 PF01610.17 EAX78561.1 - 0.038 13.7 0.4 1.8 8.2 0.0 2.0 1 1 1 2 2 2 0 Transposase MULE PF10551.9 EAX78561.1 - 0.18 12.3 0.4 0.46 10.9 0.1 1.9 2 0 0 2 2 2 0 MULE transposase domain Pox_A32 PF04665.12 EAX78563.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78563.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78563.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78563.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78564.1 - 2.3e-78 263.0 9.9 3e-78 262.6 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78565.1 - 9e-06 26.2 0.1 1.6e-05 25.4 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78566.1 - 8.8e-44 147.9 0.4 2.2e-43 146.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78566.1 - 0.0041 17.7 0.1 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX78567.1 - 4.6e-40 137.6 4.6 6.7e-40 137.1 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX78567.1 - 0.032 13.4 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ZapB PF06005.12 EAX78567.1 - 0.093 13.2 0.2 0.69 10.4 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB THOC7 PF05615.13 EAX78567.1 - 0.11 12.8 1.1 0.27 11.5 1.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4108 PF13390.6 EAX78569.1 - 1.9e-61 206.2 8.1 2.1e-61 206.0 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX78570.1 - 6e-06 26.7 0.4 8.8e-06 26.1 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78570.1 - 0.017 15.8 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78570.1 - 0.041 13.9 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX78572.1 - 0.00016 21.6 0.4 0.00016 21.6 0.4 4.2 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX78572.1 - 0.058 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX78572.1 - 0.23 11.2 5.6 0.49 10.2 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX78572.1 - 0.25 11.8 3.2 0.43 11.1 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF4106 PF13388.6 EAX78573.1 - 3.5e-269 892.9 18.7 4.4e-269 892.6 18.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78573.1 - 0.00091 19.5 0.2 0.038 14.3 0.3 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated Pox_A32 PF04665.12 EAX78574.1 - 2.2e-07 30.6 2.1 3e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78574.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78574.1 - 0.051 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78574.1 - 0.065 13.0 0.2 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2805 PF10985.8 EAX78574.1 - 0.084 13.3 1.9 0.52 10.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF4588 PF15251.6 EAX78574.1 - 0.089 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) APG12 PF04110.13 EAX78574.1 - 0.17 12.3 2.3 0.24 11.8 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3783 PF12646.7 EAX78574.1 - 0.19 11.7 2.2 1.5 8.8 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF4106 PF13388.6 EAX78575.1 - 3.6e-258 856.6 19.7 6.2e-258 855.8 19.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX78575.1 - 0.0082 16.0 0.1 0.03 14.1 0.1 2.0 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) KAR PF15222.6 EAX78575.1 - 0.022 15.0 0.1 0.91 9.8 0.2 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated SLIDE PF09111.10 EAX78575.1 - 0.45 10.6 5.1 1.1 9.3 0.6 2.8 2 0 0 2 2 2 0 SLIDE FapA PF03961.13 EAX78575.1 - 0.7 8.4 8.8 2.7 6.5 5.0 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF2939 PF11159.8 EAX78576.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX78576.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX78576.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX78577.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DASH_Dam1 PF08653.10 EAX78578.1 - 0.13 12.1 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3781 PF12636.7 EAX78579.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4108 PF13390.6 EAX78580.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78581.1 - 1.8 8.5 3.7 3.7 7.5 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX78582.1 - 6.5e-05 23.2 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78582.1 - 0.00011 22.2 3.1 0.0002 21.4 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78582.1 - 0.00046 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78582.1 - 0.00091 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78582.1 - 0.008 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78582.1 - 0.013 15.3 0.3 1.2 8.8 0.0 2.7 1 1 1 3 3 3 0 IstB-like ATP binding protein PhoH PF02562.16 EAX78582.1 - 0.047 13.1 0.1 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78582.1 - 0.094 13.1 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX78582.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3819 PF12842.7 EAX78585.1 - 0.2 11.6 4.3 0.22 11.5 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF4107 PF13389.6 EAX78587.1 - 2.2e-70 236.0 3.4 2.9e-70 235.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX78588.1 - 7.1e-57 189.3 31.3 1.5e-34 117.9 16.6 6.6 5 3 1 6 6 6 2 Phage tail repeat like DUF3391 PF11871.8 EAX78588.1 - 0.025 15.1 2.4 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX78588.1 - 0.23 11.0 21.7 0.41 10.2 6.6 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX78590.1 - 6e-121 402.4 11.1 7.4e-121 402.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78590.1 - 0.0078 16.6 1.9 1.8 9.0 0.0 3.3 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78591.1 - 6.9e-08 32.3 1.1 7.6e-08 32.1 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78591.1 - 0.0043 16.7 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78591.1 - 0.049 13.4 0.1 0.1 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78591.1 - 0.067 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX78592.1 - 0.044 14.3 0.3 0.084 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX78592.1 - 0.45 10.6 3.3 9.9 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX78593.1 - 6.5e-33 112.6 18.3 5.5e-32 109.6 14.3 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4404 PF14357.6 EAX78593.1 - 2.7 8.7 5.3 12 6.6 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Pox_A32 PF04665.12 EAX78594.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78594.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78594.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78594.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78594.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78594.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DAO_C PF16901.5 EAX78596.1 - 0.078 12.8 0.0 0.084 12.7 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF3464 PF11947.8 EAX78596.1 - 0.18 11.5 2.2 0.18 11.5 2.2 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX78596.1 - 0.59 10.1 3.4 0.71 9.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX78597.1 - 1.1e-57 193.9 5.9 1.2e-57 193.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78597.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Mito_fiss_reg PF05308.11 EAX78598.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX78598.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FliJ PF02050.16 EAX78599.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein PTR PF12789.7 EAX78601.1 - 2.5e-51 171.5 35.0 1.1e-32 111.8 15.2 5.1 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX78601.1 - 0.039 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) ComA PF02679.15 EAX78603.1 - 0.085 12.3 1.0 0.1 12.1 1.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF3839 PF12943.7 EAX78604.1 - 1.4e-65 221.1 5.8 1.9e-65 220.7 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78604.1 - 0.011 16.2 0.4 0.013 15.9 0.4 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX78604.1 - 0.039 14.5 0.6 0.055 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) BRE1 PF08647.11 EAX78604.1 - 0.18 11.9 3.7 2.3 8.4 1.4 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4107 PF13389.6 EAX78605.1 - 3.9e-72 241.7 3.6 5.1e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX78606.1 - 3.1e-41 139.7 1.3 4.4e-41 139.2 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78606.1 - 0.031 14.5 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78607.1 - 1.9e-07 30.8 2.4 1.9e-07 30.8 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78607.1 - 3.3e-05 24.2 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78607.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78607.1 - 0.00023 21.2 3.9 0.0005 20.1 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78607.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78607.1 - 0.0014 18.4 0.7 0.0027 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78607.1 - 0.002 17.8 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78607.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX78607.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78607.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78607.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78607.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX78608.1 - 9.9e-139 460.7 6.8 1.1e-138 460.5 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Gly-zipper_Omp PF13488.6 EAX78609.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX78609.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX78609.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX78611.1 - 8.6e-43 146.5 3.6 1.1e-42 146.2 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78612.1 - 0.00029 21.3 0.1 0.00061 20.3 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain PSP PF04046.16 EAX78613.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX78614.1 - 0.029 14.8 5.7 4.6 8.3 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX78615.1 - 0.031 14.7 0.8 0.062 13.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DNA_pol_B_2 PF03175.13 EAX78616.1 - 6.8e-29 101.0 7.6 1.2e-28 100.3 7.6 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78616.1 - 0.048 13.0 0.2 0.08 12.2 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX78617.1 - 1.7e-06 28.5 0.1 3.2e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78618.1 - 7.8e-40 135.2 0.6 1.4e-39 134.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78618.1 - 0.014 16.0 0.2 0.033 14.8 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DDR PF08841.10 EAX78619.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX78619.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX78620.1 - 0.063 13.2 10.3 0.089 12.8 10.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX78621.1 - 4.4e-45 152.1 0.1 4.4e-45 152.1 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78621.1 - 0.027 14.6 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78622.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78622.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78622.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78622.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78622.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78622.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX78623.1 - 1.8e-61 206.2 9.1 2e-61 206.1 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PDCD9 PF07147.12 EAX78624.1 - 0.059 12.6 0.6 0.067 12.4 0.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) DNA_pol_B_2 PF03175.13 EAX78625.1 - 2.8e-09 36.4 1.1 4.9e-09 35.6 0.9 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ribosomal_S6e PF01092.19 EAX78625.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S6e Lac_bphage_repr PF06543.12 EAX78625.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX78626.1 - 9.8e-78 260.9 8.9 1.2e-77 260.6 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX78626.1 - 0.06 13.9 2.3 0.11 13.1 2.3 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr KilA-N PF04383.13 EAX78627.1 - 8.5e-43 144.8 0.7 1.5e-42 144.0 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78627.1 - 0.0076 16.9 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Parathyroid hormone family FAS_N PF17828.1 EAX78628.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX78629.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX78629.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PTR PF12789.7 EAX78630.1 - 4e-59 196.6 41.2 3.4e-31 107.1 14.3 4.0 2 1 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX78630.1 - 0.045 13.5 0.9 0.087 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX78631.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Tmemb_9 PF05434.11 EAX78633.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 Trypan_PARP PF05887.11 EAX78636.1 - 0.036 14.1 8.2 0.056 13.4 8.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX78636.1 - 2.7 8.4 5.3 3.9 7.9 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX78637.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78637.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX78640.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX78642.1 - 1.3e-58 197.0 4.6 1.4e-58 196.9 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78642.1 - 0.1 12.8 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX78643.1 - 1.3e-05 25.6 2.6 7.8e-05 23.1 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78643.1 - 0.067 13.8 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78643.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Gly-zipper_Omp PF13488.6 EAX78645.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX78645.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX78645.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif KilA-N PF04383.13 EAX78647.1 - 7.6e-26 90.2 0.6 1.8e-25 89.0 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX78648.1 - 1.8e-158 525.3 13.8 2.3e-158 525.0 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78648.1 - 0.095 13.1 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78648.1 - 2.4 8.7 8.4 2.6 8.6 0.9 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Peptidase_M8 PF01457.16 EAX78650.1 - 2.4e-18 66.1 0.0 4.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.24 EAX78650.1 - 7e-06 26.0 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain DUF3839 PF12943.7 EAX78651.1 - 1.1e-79 267.3 9.3 1.4e-79 266.9 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX78654.1 - 0.044 13.7 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX78654.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX78656.1 - 3.6e-80 268.9 9.9 4.6e-80 268.6 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78656.1 - 0.087 12.3 0.6 0.41 10.1 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 DUF4106 PF13388.6 EAX78657.1 - 2.3e-276 916.5 59.7 7.3e-152 506.4 20.8 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78657.1 - 0.023 15.0 0.1 0.86 9.9 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated Zds_C PF08632.10 EAX78658.1 - 0.034 13.9 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term YvrJ PF12841.7 EAX78659.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family FliD_N PF02465.18 EAX78660.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX78660.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Polysacc_deac_1 PF01522.21 EAX78661.1 - 0.012 15.6 0.3 0.014 15.3 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF3839 PF12943.7 EAX78662.1 - 1.2e-16 60.9 3.3 1.9e-16 60.3 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78662.1 - 0.051 13.9 0.5 0.14 12.4 0.1 1.9 1 1 1 2 2 2 0 PRD domain DUF4378 PF14309.6 EAX78664.1 - 0.011 16.1 0.1 0.058 13.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) KilA-N PF04383.13 EAX78665.1 - 2.7e-41 139.9 1.1 4.1e-41 139.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78665.1 - 0.031 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX78666.1 - 6.7e-122 405.6 12.5 8.4e-122 405.2 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78666.1 - 0.018 15.5 2.7 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF29 PF01724.16 EAX78666.1 - 0.052 13.8 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX78666.1 - 0.18 11.6 1.7 0.53 10.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX78667.1 - 2.2e-50 171.0 2.2 2.6e-50 170.7 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX78667.1 - 0.033 12.6 1.1 0.041 12.3 1.1 1.1 1 0 0 1 1 1 0 Lipoxygenase PSP PF04046.16 EAX78668.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX78669.1 - 0.33 11.7 7.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX78669.1 - 5.9 6.9 8.4 6.3 6.8 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX78672.1 - 8.8e-07 28.6 0.4 6.8e-06 25.7 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX78672.1 - 0.066 12.8 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX78672.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX78672.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EAX78674.1 - 0.002 17.1 14.7 0.002 17.1 14.7 4.0 1 1 3 4 4 4 2 Spc7 kinetochore protein BLOC1_2 PF10046.9 EAX78674.1 - 0.016 15.5 5.4 0.016 15.5 5.4 4.9 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.12 EAX78674.1 - 0.074 11.2 49.9 0.12 10.6 30.9 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 EAX78674.1 - 0.12 12.5 42.5 0.1 12.6 7.5 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SAB PF04382.13 EAX78674.1 - 0.27 11.4 0.1 0.27 11.4 0.1 4.6 4 1 1 5 5 5 0 SAB domain WEMBL PF05701.11 EAX78674.1 - 0.42 9.2 49.4 0.54 8.9 30.5 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light MAD PF05557.13 EAX78674.1 - 0.59 8.4 51.8 2.7 6.2 32.0 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4201 PF13870.6 EAX78674.1 - 0.72 9.6 52.5 0.4 10.4 5.8 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.22 EAX78674.1 - 0.77 10.0 54.3 0.1 12.8 10.1 4.9 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain MCPsignal PF00015.21 EAX78674.1 - 0.83 9.4 37.0 0.93 9.3 8.5 3.7 2 2 1 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUSC PF04632.12 EAX78674.1 - 0.99 7.9 4.9 0.35 9.3 1.3 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family HOOK PF05622.12 EAX78674.1 - 3.3 5.7 49.3 0.051 11.7 17.3 2.8 1 1 2 3 3 3 0 HOOK protein TMPIT PF07851.13 EAX78674.1 - 4.5 6.4 47.8 0.062 12.5 10.9 4.0 1 1 3 4 4 4 0 TMPIT-like protein Fez1 PF06818.15 EAX78674.1 - 4.5 7.7 46.9 10 6.5 19.6 3.0 1 1 2 3 3 3 0 Fez1 Filament PF00038.21 EAX78674.1 - 4.6 6.7 49.0 2.2 7.8 11.5 3.8 1 1 2 3 3 3 0 Intermediate filament protein DUF4200 PF13863.6 EAX78674.1 - 4.6 7.7 54.1 11 6.4 14.1 4.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) CALCOCO1 PF07888.11 EAX78674.1 - 4.7 6.0 46.7 0.053 12.4 34.1 2.7 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_I PF06008.14 EAX78674.1 - 4.7 6.8 52.0 0.67 9.6 10.8 4.9 1 1 3 5 5 5 0 Laminin Domain I DUF812 PF05667.11 EAX78674.1 - 5.6 5.7 53.7 5.7 5.7 29.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.9 EAX78674.1 - 9 5.3 47.6 36 3.3 13.7 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A32 PF04665.12 EAX78675.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX78675.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Amidase02_C PF12123.8 EAX78676.1 - 0.0099 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX78680.1 - 2.4e-05 23.7 0.1 2.4e-05 23.7 0.1 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) Polysacc_deac_1 PF01522.21 EAX78680.1 - 0.15 11.9 3.2 2.5 8.0 0.9 3.4 1 1 2 3 3 3 0 Polysaccharide deacetylase WYL_3 PF18488.1 EAX78680.1 - 0.84 10.1 11.8 14 6.2 2.6 3.8 2 1 1 3 3 3 0 WYL domain GPS2_interact PF15784.5 EAX78682.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78682.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX78684.1 - 2e-16 59.7 3.8 2e-16 59.7 3.8 3.7 2 1 1 4 4 4 1 Phage tail repeat like Myc_N PF01056.18 EAX78685.1 - 0.1 12.5 1.4 0.12 12.3 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 EAX78685.1 - 3.6 8.0 15.4 11 6.5 0.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 EAX78686.1 - 9.5e-13 48.5 3.0 3.2e-12 46.9 0.9 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX78686.1 - 1.8e-10 41.1 1.9 4.5e-06 27.1 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX78686.1 - 1.9e-10 40.0 0.2 0.1 13.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX78686.1 - 2.9e-10 40.2 1.3 3.7e-06 27.1 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX78686.1 - 4.7e-05 23.6 0.2 0.94 10.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 EAX78687.1 - 2.5e-41 140.0 0.4 7.3e-41 138.5 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX78690.1 - 4.8e-30 103.7 0.2 4.8e-30 103.7 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX78690.1 - 0.02 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78691.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78691.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78691.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78691.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78692.1 - 1.8e-121 404.1 13.3 2.3e-121 403.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78692.1 - 0.031 14.7 2.7 1.8 9.0 0.0 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX78692.1 - 0.093 12.2 0.5 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX78692.1 - 0.18 11.6 1.5 0.59 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PapD_N PF00345.20 EAX78693.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX78693.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family FliD_N PF02465.18 EAX78695.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX78695.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HC2 PF07382.11 EAX78696.1 - 1.3e-07 31.9 12.4 1.5e-07 31.7 12.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX78696.1 - 4.2e-05 23.6 0.5 5.1e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Aurora-A_bind PF09041.10 EAX78696.1 - 0.96 9.6 8.7 2.3e+02 1.9 8.7 3.1 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX78696.1 - 1.8 8.6 5.1 71 3.5 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) YvrJ PF12841.7 EAX78697.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family DNA_pol_B_2 PF03175.13 EAX78699.1 - 6.1e-25 88.0 10.1 2.3e-24 86.1 10.1 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX78700.1 - 1.2e-47 159.8 28.3 3.4e-31 107.1 13.2 4.6 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX78700.1 - 0.027 14.2 1.0 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX78700.1 - 0.5 10.7 4.1 18 5.7 0.3 3.7 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain Amidase02_C PF12123.8 EAX78701.1 - 0.0034 17.1 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX78702.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78702.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Nucleopor_Nup85 PF07575.13 EAX78703.1 - 0.0036 15.9 0.0 0.006 15.2 0.0 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin Pox_D5 PF03288.16 EAX78706.1 - 6.9e-05 23.3 2.9 0.00034 21.1 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX78706.1 - 0.028 15.0 0.1 0.057 14.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78706.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Chal_sti_synt_N PF00195.19 EAX78707.1 - 0.014 14.8 1.1 0.028 13.8 1.1 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain WASH-7_C PF14746.6 EAX78708.1 - 0.043 13.5 4.6 0.11 12.2 1.1 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX78708.1 - 0.25 11.6 5.6 0.72 10.1 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX78708.1 - 0.51 10.1 5.3 0.8 9.5 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KilA-N PF04383.13 EAX78709.1 - 7.4e-15 54.8 0.2 1.5e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain DOCK-C2 PF14429.6 EAX78710.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins KilA-N PF04383.13 EAX78711.1 - 3.3e-43 146.1 0.5 9.1e-43 144.7 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX78712.1 - 6.1e-07 29.9 0.6 1.9e-06 28.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX78712.1 - 0.14 11.6 0.2 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAX78713.1 - 2.9e-07 30.2 4.3 7.8e-07 28.8 4.3 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78713.1 - 0.0043 16.7 0.1 0.0057 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78713.1 - 0.066 12.9 0.1 0.24 11.1 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein APG12 PF04110.13 EAX78713.1 - 0.18 12.3 1.9 0.28 11.6 0.7 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3783 PF12646.7 EAX78713.1 - 0.18 11.8 1.7 1.2 9.1 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78715.1 - 2.4e-156 518.3 13.5 2.8e-156 518.1 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78715.1 - 0.084 12.7 0.5 0.2 11.5 0.5 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX78715.1 - 0.086 13.1 0.6 1.3 9.4 0.0 2.8 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX78715.1 - 2.3 8.8 7.7 1.8 9.1 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78716.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78716.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78716.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78716.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78717.1 - 2.8e-121 403.5 13.4 3.5e-121 403.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78717.1 - 0.024 15.1 2.5 1.8 9.0 0.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX78717.1 - 0.093 12.2 0.6 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX78717.1 - 0.22 11.4 1.9 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4124 PF13511.6 EAX78718.1 - 0.00088 19.6 0.0 22 5.5 0.0 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4124) DUF4980 PF16352.5 EAX78718.1 - 0.0047 16.9 0.7 3.5 7.7 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4980) TQ PF18202.1 EAX78718.1 - 0.014 15.9 17.0 0.53 10.8 4.8 2.7 1 1 1 2 2 2 0 T-Q ester bond containing domain Chordopox_G3 PF06129.12 EAX78718.1 - 0.018 15.8 5.2 2.3 8.9 0.2 2.8 3 0 0 3 3 3 0 Chordopoxvirus G3 protein DUF3474 PF11960.8 EAX78718.1 - 0.02 15.1 2.0 4.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) SPG4 PF17325.2 EAX78718.1 - 0.025 15.7 4.4 3 9.0 0.4 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 Kunitz_legume PF00197.18 EAX78718.1 - 0.043 13.8 1.7 6.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Trypsin and protease inhibitor CBM60 PF16841.5 EAX78718.1 - 0.12 12.8 3.8 9.9 6.7 0.3 2.7 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding LOR PF04525.12 EAX78718.1 - 0.17 11.4 4.3 5.2 6.6 0.3 2.2 2 0 0 2 2 2 0 LURP-one-related PQQ PF01011.21 EAX78718.1 - 0.21 11.6 1.1 37 4.5 0.1 3.2 2 0 0 2 2 2 0 PQQ enzyme repeat BppL_N PF18338.1 EAX78718.1 - 0.37 10.6 8.9 15 5.5 0.0 4.7 6 0 0 6 6 6 0 Lower baseplate protein N-terminal domain Alpha_GJ PF03229.13 EAX78718.1 - 5 7.7 10.1 13 6.4 1.5 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J DNA_pol_B_2 PF03175.13 EAX78719.1 - 6.5e-29 101.1 7.6 1.1e-28 100.4 7.6 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX78719.1 - 0.03 13.6 0.2 0.05 12.9 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5106 PF17127.4 EAX78719.1 - 0.039 14.2 0.1 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DUF5065 PF16723.5 EAX78719.1 - 0.081 13.0 1.0 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) RRM_1 PF00076.22 EAX78721.1 - 8.9e-19 67.1 0.1 6e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAX78721.1 - 0.0092 16.2 0.0 2.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 EAX78721.1 - 0.064 13.5 0.0 3 8.1 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 DUF3839 PF12943.7 EAX78722.1 - 7.1e-151 500.4 12.6 1e-150 499.9 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78722.1 - 0.0053 17.3 0.3 0.079 13.5 0.2 2.9 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX78722.1 - 0.029 14.9 1.0 0.076 13.5 0.1 1.9 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX78722.1 - 0.078 13.4 0.6 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78722.1 - 0.71 10.4 5.3 2.8 8.4 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MULE PF10551.9 EAX78723.1 - 4.3e-09 36.7 0.1 1e-08 35.5 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX78723.1 - 0.047 14.4 0.1 0.097 13.4 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain Baculo_E66 PF04850.12 EAX78723.1 - 0.096 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein DUF3839 PF12943.7 EAX78724.1 - 3.9e-25 88.7 5.0 6.2e-25 88.1 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78724.1 - 0.056 13.8 0.7 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX78724.1 - 0.066 13.7 0.8 0.37 11.3 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX78725.1 - 1.5e-37 127.9 1.0 2.7e-37 127.0 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78725.1 - 0.0029 18.2 0.1 0.0091 16.6 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX78726.1 - 6.3e-07 29.1 2.6 6.3e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78726.1 - 2.3e-05 24.7 0.2 0.00017 21.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX78726.1 - 6.9e-05 22.9 1.9 0.00015 21.8 1.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX78726.1 - 7.4e-05 22.5 0.2 0.38 10.5 0.0 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX78726.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78726.1 - 0.0015 18.4 0.4 0.0026 17.6 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78726.1 - 0.0019 17.8 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78726.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX78726.1 - 0.062 12.8 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX78726.1 - 0.067 12.9 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX78726.1 - 0.073 12.6 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX78726.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX78726.1 - 0.1 13.0 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78726.1 - 0.46 10.7 3.7 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX78727.1 - 2.1e-25 89.6 4.5 3.3e-25 88.9 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX78728.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX78728.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MAP7 PF05672.11 EAX78730.1 - 4.3 7.0 60.0 0.17 11.6 51.0 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF3839 PF12943.7 EAX78731.1 - 3.7e-138 458.8 8.6 4.3e-138 458.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2939 PF11159.8 EAX78733.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX78733.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PadR PF03551.14 EAX78734.1 - 0.078 12.9 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX78736.1 - 9.4e-25 87.5 4.0 1.4e-24 86.9 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78736.1 - 0.046 14.0 0.8 0.18 12.1 0.1 2.1 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX78736.1 - 0.097 13.1 1.1 0.41 11.1 0.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF3781 PF12636.7 EAX78737.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DNA_pol_B_2 PF03175.13 EAX78738.1 - 3.3e-11 42.7 1.5 3.3e-11 42.7 1.5 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral TFCD_C PF12612.8 EAX78738.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF4108 PF13390.6 EAX78740.1 - 1.9e-60 202.9 8.4 2.1e-60 202.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX78741.1 - 1.7e-149 495.9 14.7 2.1e-149 495.6 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78741.1 - 0.044 14.2 2.2 0.14 12.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX78741.1 - 0.23 11.9 6.6 1.6 9.3 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX78741.1 - 1.3 9.5 7.0 0.28 11.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Ank_4 PF13637.6 EAX78743.1 - 1e-11 45.1 1.3 3.5e-06 27.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX78743.1 - 1.8e-11 44.4 0.3 2e-11 44.3 0.3 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX78743.1 - 8.8e-08 32.3 4.4 7.4e-05 23.0 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX78743.1 - 5.2e-07 29.5 0.1 8.3e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAX78743.1 - 5.2e-07 29.8 0.2 7.6e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3839 PF12943.7 EAX78744.1 - 6.3e-159 526.8 12.4 8.1e-159 526.4 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX78744.1 - 0.2 12.1 2.9 0.26 11.7 0.6 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX78744.1 - 0.27 11.7 7.3 2 8.9 0.4 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX78744.1 - 0.9 9.9 6.1 12 6.3 0.1 4.0 4 1 1 5 5 5 0 Tup N-terminal DUF4107 PF13389.6 EAX78745.1 - 1.7e-66 223.4 12.1 1.1e-65 220.7 12.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78745.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Ribosomal_L6e PF01159.19 EAX78747.1 - 1.1 9.8 8.5 1.1 9.9 0.1 2.9 2 1 1 3 3 3 0 Ribosomal protein L6e PapD_N PF00345.20 EAX78749.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX78751.1 - 1.3e-28 100.1 6.5 1.9e-28 99.5 6.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX78751.1 - 0.074 12.2 0.1 0.094 11.9 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II PRD PF00874.20 EAX78751.1 - 0.078 13.3 0.6 0.29 11.4 0.1 2.0 1 1 1 2 2 2 0 PRD domain DUF4107 PF13389.6 EAX78752.1 - 2.3e-64 216.4 2.4 3.1e-64 216.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MG2 PF01835.19 EAX78753.1 - 7.3e-06 26.3 2.1 0.012 16.0 0.1 3.7 4 0 0 4 4 4 1 MG2 domain DUF4625 PF15418.6 EAX78753.1 - 8.5e-05 22.8 3.2 0.05 13.8 0.1 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX78753.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Chitinase A, N-terminal domain NPCBM_assoc PF10633.9 EAX78753.1 - 0.018 15.2 3.7 0.13 12.5 0.1 3.6 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase He_PIG PF05345.12 EAX78753.1 - 0.033 14.4 0.4 0.48 10.7 0.1 2.9 2 0 0 2 2 2 0 Putative Ig domain DUF2914 PF11141.8 EAX78753.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) bMG6 PF17962.1 EAX78753.1 - 0.11 12.6 1.1 6.8 6.9 0.1 3.2 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 RIFIN PF02009.16 EAX78753.1 - 0.37 10.6 7.3 0.59 10.0 7.3 1.3 1 0 0 1 1 1 0 Rifin DUF2897 PF11446.8 EAX78754.1 - 0.71 9.8 2.9 1.4 8.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX78755.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX78757.1 - 5.7e-39 134.0 4.3 7.8e-39 133.6 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX78758.1 - 9.6e-06 26.1 0.2 2.6e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX78758.1 - 0.0024 17.4 0.5 0.24 10.9 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX78758.1 - 0.0057 16.5 0.0 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain PadR PF03551.14 EAX78760.1 - 0.067 13.2 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX78761.1 - 7.4e-30 102.8 12.5 7.4e-30 102.8 12.5 3.8 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX78761.1 - 0.32 10.8 0.1 0.32 10.8 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX78763.1 - 1.4e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX78764.1 - 0.29 11.0 3.2 0.63 10.0 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX78766.1 - 2e-05 25.0 2.6 0.00014 22.3 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX78767.1 - 5.6e-64 214.4 7.0 6.2e-64 214.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX78767.1 - 0.12 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX78768.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PTR PF12789.7 EAX78770.1 - 1.8e-48 162.4 30.8 3.2e-32 110.4 15.7 4.2 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX78770.1 - 0.019 14.7 0.4 0.14 12.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX78783.1 - 6.5e-157 520.2 12.3 8.1e-157 519.9 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78783.1 - 0.072 13.5 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78783.1 - 0.42 11.1 8.0 2.6 8.6 0.9 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78784.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX78784.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX78785.1 - 1.8e-149 495.9 16.1 2.2e-149 495.6 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX78785.1 - 0.13 12.5 0.7 2.5 8.5 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX78785.1 - 0.2 11.5 1.4 0.54 10.1 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78785.1 - 0.3 11.6 6.6 2.2 8.8 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX78785.1 - 0.79 10.3 5.9 0.61 10.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX78786.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78786.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78786.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78786.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX78787.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.9 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX78787.1 - 0.027 14.2 0.1 0.095 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX78787.1 - 0.27 11.0 10.1 0.3 10.8 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX78787.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAX78788.1 - 1.7e-155 515.5 12.7 2.2e-155 515.2 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78788.1 - 0.11 12.3 0.8 0.34 10.8 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PapD_N PF00345.20 EAX78790.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX78790.1 - 0.13 12.3 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX78792.1 - 2.4e-155 515.1 11.5 3e-155 514.7 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78792.1 - 0.1 12.4 0.9 0.37 10.6 0.9 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX78792.1 - 0.43 10.9 4.4 1.8 8.9 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX78792.1 - 1.7 9.1 6.2 3.3 8.2 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDR PF08841.10 EAX78793.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Fusion_gly PF00523.18 EAX78794.1 - 0.0046 15.3 1.9 0.0055 15.0 1.9 1.0 1 0 0 1 1 1 1 Fusion glycoprotein F0 ETRAMP PF09716.10 EAX78794.1 - 0.34 11.0 2.2 0.49 10.5 2.2 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) JIP_LZII PF16471.5 EAX78795.1 - 0.00085 19.5 2.8 0.00085 19.5 2.8 3.7 3 2 1 4 4 4 2 JNK-interacting protein leucine zipper II CCDC144C PF14915.6 EAX78795.1 - 0.0035 16.5 33.5 0.0052 15.9 33.5 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region STE PF02200.16 EAX78795.1 - 0.0065 16.9 1.3 0.016 15.7 0.7 1.9 1 1 1 2 2 2 1 STE like transcription factor DUF3584 PF12128.8 EAX78795.1 - 0.024 12.2 31.5 0.028 12.0 31.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 EAX78795.1 - 0.13 12.7 19.3 0.27 11.7 12.9 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB PIN_8 PF18476.1 EAX78795.1 - 0.22 11.3 23.5 0.24 11.3 11.1 2.1 1 1 1 2 2 2 0 PIN like domain ArgoMid PF16487.5 EAX78795.1 - 0.34 11.2 4.1 0.6 10.4 0.3 2.6 1 1 2 3 3 3 0 Mid domain of argonaute Thioredoxin_8 PF13905.6 EAX78795.1 - 1.7 9.0 6.9 0.54 10.6 1.2 2.5 1 1 1 2 2 2 0 Thioredoxin-like HAUS-augmin3 PF14932.6 EAX78795.1 - 3.3 7.2 32.1 8.9 5.8 20.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DAGK_cat PF00781.24 EAX78795.1 - 5.1 6.7 8.5 2.7 7.6 0.3 2.7 1 1 2 3 3 3 0 Diacylglycerol kinase catalytic domain RecG_N PF17190.4 EAX78795.1 - 6.4 7.6 21.3 7.6 7.3 3.0 3.0 1 1 2 3 3 3 0 RecG N-terminal helical domain DUF1664 PF07889.12 EAX78795.1 - 9.9 6.2 23.9 4.5 7.3 3.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) T5orf172 PF10544.9 EAX78796.1 - 4.3e-06 27.2 0.2 9.5e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78797.1 - 1.3e-42 144.1 0.1 1.9e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Trypan_PARP PF05887.11 EAX78798.1 - 0.094 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX78800.1 - 4.8e-29 101.5 7.4 6.9e-29 101.0 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX78800.1 - 0.069 13.3 0.1 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers KilA-N PF04383.13 EAX78801.1 - 1.3e-32 112.0 0.1 2.7e-32 110.9 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF5568 PF17724.1 EAX78801.1 - 0.16 11.8 0.1 1.2 8.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5568) FAS_N PF17828.1 EAX78803.1 - 0.0047 16.9 0.4 0.0067 16.4 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX78804.1 - 0.0052 17.2 0.7 0.0063 16.9 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX78804.1 - 2.3 8.2 6.6 2.5 8.1 6.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 KilA-N PF04383.13 EAX78805.1 - 4.2e-39 132.9 1.3 6.3e-39 132.3 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78805.1 - 0.0024 18.4 0.4 0.012 16.2 0.0 2.2 2 0 0 2 2 2 1 Parathyroid hormone family T5orf172 PF10544.9 EAX78806.1 - 2.8e-07 31.0 0.3 6.7e-07 29.8 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78806.1 - 0.03 14.2 2.6 0.07 13.0 0.8 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX78806.1 - 0.047 13.2 0.9 0.54 9.8 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF2939 PF11159.8 EAX78807.1 - 0.017 15.5 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78807.1 - 1.3 8.0 3.0 1.4 7.9 3.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX78807.1 - 3 7.8 6.2 3.2 7.7 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX78808.1 - 0.006 16.6 0.2 0.008 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DHC_N2 PF08393.13 EAX78809.1 - 5.9e-101 338.4 16.7 5.9e-101 338.4 16.7 2.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 PTH2 PF01981.16 EAX78809.1 - 0.37 11.1 2.2 0.59 10.4 0.5 2.3 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 DUF4108 PF13390.6 EAX78810.1 - 2.9e-61 205.6 8.4 3.2e-61 205.4 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX78811.1 - 0.097 12.4 0.0 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX78811.1 - 0.59 10.4 15.3 0.83 9.9 15.3 1.4 1 1 0 1 1 1 0 PcfK-like protein PBP_sp32 PF07222.12 EAX78811.1 - 1.1 8.6 9.2 1.7 8.1 9.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ResIII PF04851.15 EAX78812.1 - 2.2e-05 24.5 0.2 2.8e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78812.1 - 0.00026 20.8 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX78812.1 - 0.00069 19.9 0.0 0.00094 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX78812.1 - 0.0018 18.1 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX78812.1 - 0.0064 16.8 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX78812.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX78812.1 - 0.068 12.9 0.0 0.085 12.6 0.0 1.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX78812.1 - 0.083 12.5 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX78812.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX78812.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mito_fiss_reg PF05308.11 EAX78813.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX78813.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Big_8 PF17961.1 EAX78814.1 - 0.024 14.7 0.3 0.06 13.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig domain B3R PF17057.5 EAX78814.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxviridae B3 protein SH3_5 PF08460.10 EAX78814.1 - 0.059 13.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain DUF4106 PF13388.6 EAX78815.1 - 7.4e-268 888.5 20.1 1.1e-267 887.9 20.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78815.1 - 0.022 15.0 0.1 1.1 9.6 0.1 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated WYL_3 PF18488.1 EAX78815.1 - 1.7 9.1 6.8 11 6.5 0.4 3.2 3 0 0 3 3 3 0 WYL domain WBS_methylT PF12589.8 EAX78815.1 - 6.6 7.6 9.5 33 5.3 1.8 3.2 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF3839 PF12943.7 EAX78817.1 - 5.9e-156 517.0 13.0 6.9e-156 516.8 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78817.1 - 0.15 11.9 0.9 0.42 10.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78817.1 - 2.1 8.9 6.2 3.6 8.1 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX78818.1 - 1.8e-120 400.8 11.9 2.3e-120 400.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78818.1 - 0.041 14.3 2.8 1.6 9.2 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX78818.1 - 0.047 13.6 1.0 0.19 11.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase FAS_N PF17828.1 EAX78819.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX78820.1 - 0.031 14.7 1.4 0.032 14.6 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX78820.1 - 2.4 7.1 5.7 2.4 7.1 5.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF2400 PF09674.10 EAX78821.1 - 0.025 14.6 0.6 0.036 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX78821.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX78824.1 - 2.6e-09 36.5 0.8 5e-09 35.5 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX78824.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Amidase02_C PF12123.8 EAX78825.1 - 0.0085 15.8 0.1 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DDA1 PF10172.9 EAX78826.1 - 0.41 11.0 10.9 4 7.8 2.6 3.7 2 1 2 4 4 4 0 Det1 complexing ubiquitin ligase EpuA PF11772.8 EAX78827.1 - 0.033 13.9 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF3839 PF12943.7 EAX78828.1 - 2.9e-157 521.4 14.2 3.6e-157 521.0 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78828.1 - 0.15 11.9 1.5 0.48 10.3 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78828.1 - 2.6 8.6 8.0 1.9 9.0 1.1 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX78831.1 - 9.7e-17 60.8 1.9 9.7e-17 60.8 1.9 4.4 4 1 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX78831.1 - 0.05 13.2 8.8 0.065 12.8 6.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX78831.1 - 0.066 13.7 2.0 0.097 13.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3839 PF12943.7 EAX78832.1 - 3.6e-25 88.8 4.6 5.2e-25 88.3 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ntox23 PF15528.6 EAX78833.1 - 0.02 15.1 2.3 0.024 14.8 2.3 1.1 1 0 0 1 1 1 0 Bacterial toxin 23 YL1 PF05764.13 EAX78833.1 - 0.038 14.1 11.8 0.044 13.9 11.8 1.0 1 0 0 1 1 1 0 YL1 nuclear protein TMEM43 PF07787.12 EAX78833.1 - 0.36 10.2 2.2 0.41 10.0 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 Osteopontin PF00865.18 EAX78833.1 - 0.46 9.9 15.2 0.55 9.7 15.2 1.2 1 0 0 1 1 1 0 Osteopontin Rsc14 PF08586.10 EAX78833.1 - 0.77 10.6 4.7 0.5 11.2 2.2 1.8 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit CDC45 PF02724.14 EAX78833.1 - 0.8 7.9 10.8 0.9 7.7 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EAX78833.1 - 1.4 7.4 10.4 1.4 7.4 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EAX78833.1 - 2 6.4 13.8 2 6.4 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EAX78833.1 - 4.2 5.5 14.0 4.6 5.3 14.0 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_B_2 PF03175.13 EAX78834.1 - 4.4e-29 101.7 8.9 7.6e-29 100.9 8.9 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Aldo_ket_red PF00248.21 EAX78835.1 - 4.3e-39 134.5 0.0 4.9e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pox_A32 PF04665.12 EAX78836.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78836.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78836.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78836.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78836.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78836.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78836.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78836.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX78836.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX78836.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78836.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78836.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78836.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Cir_Bir_Yir PF06022.11 EAX78838.1 - 0.023 14.2 2.0 0.034 13.6 2.0 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir HAUS-augmin3 PF14932.6 EAX78838.1 - 0.057 13.0 1.1 0.12 12.0 1.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pox_A32 PF04665.12 EAX78839.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78839.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78839.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78839.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78839.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78839.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX78840.1 - 3.5e-43 146.0 0.3 8.7e-43 144.7 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78840.1 - 0.06 14.0 0.1 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX78841.1 - 1.8e-06 28.4 0.0 4.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78841.1 - 0.0043 16.9 1.2 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX78842.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78842.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78842.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78842.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX78843.1 - 5e-53 180.0 5.8 6.6e-53 179.6 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX78843.1 - 0.0038 17.3 0.6 2.2 8.3 0.2 2.3 1 1 1 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 EAX78843.1 - 0.012 16.1 0.4 0.013 15.9 0.4 1.1 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX78843.1 - 0.069 13.7 0.6 0.085 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX78843.1 - 0.14 12.7 1.2 0.72 10.3 0.9 2.3 2 1 0 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 EAX78843.1 - 0.2 11.8 4.6 4 7.6 4.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase WRKY PF03106.15 EAX78845.1 - 0.04 14.1 0.8 0.04 14.1 0.8 2.9 2 1 1 3 3 3 0 WRKY DNA -binding domain DUF3839 PF12943.7 EAX78846.1 - 1.2e-16 60.9 3.4 2e-16 60.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78846.1 - 0.056 13.7 0.5 0.13 12.6 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX78846.1 - 0.078 13.4 1.4 0.29 11.6 0.4 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF2362 PF10154.9 EAX78847.1 - 0.012 14.6 6.9 0.015 14.3 6.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) MBD PF01429.19 EAX78847.1 - 0.45 10.3 1.8 80 3.1 0.1 3.2 3 0 0 3 3 3 0 Methyl-CpG binding domain ChlamPMP_M PF07548.11 EAX78847.1 - 0.74 9.7 9.7 1.7 8.5 9.7 1.5 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain AMPKBI PF04739.15 EAX78847.1 - 1.9 8.8 21.4 12 6.2 0.5 4.1 1 1 2 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain T5orf172 PF10544.9 EAX78848.1 - 1.1e-06 29.0 0.2 3e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX78848.1 - 0.045 13.3 0.1 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3213 PF11491.8 EAX78850.1 - 0.031 14.5 0.5 0.072 13.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX78852.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78852.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78852.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78852.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78852.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78852.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78852.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX78853.1 - 0.00063 20.3 0.1 0.0013 19.3 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX78853.1 - 0.071 12.6 0.6 0.73 9.3 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Gly-zipper_Omp PF13488.6 EAX78854.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX78854.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF3839 PF12943.7 EAX78855.1 - 4.4e-93 311.2 8.3 4.9e-93 311.0 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78855.1 - 0.18 12.3 1.5 0.58 10.7 1.5 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX78856.1 - 6.5e-30 104.4 5.7 1.6e-27 96.6 5.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX78856.1 - 0.26 9.6 1.0 0.28 9.6 1.0 1.0 1 0 0 1 1 1 0 Lipoxygenase KilA-N PF04383.13 EAX78857.1 - 8.4e-07 28.8 0.2 8.4e-07 28.8 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX78857.1 - 0.0032 18.1 0.0 0.0065 17.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX78858.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78858.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78858.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78858.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78858.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78858.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX78859.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78859.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78859.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78859.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78859.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78859.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78859.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78859.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX78859.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX78859.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78859.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78859.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78859.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) MULE PF10551.9 EAX78860.1 - 0.00064 20.1 0.0 0.00091 19.6 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain LuxE PF04443.12 EAX78860.1 - 0.017 14.2 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE GLF PF03275.13 EAX78860.1 - 0.069 12.9 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 UDP-galactopyranose mutase Transposase_mut PF00872.18 EAX78860.1 - 0.1 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX78861.1 - 2.7e-79 266.0 8.7 3.5e-79 265.7 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX78862.1 - 2e-07 30.8 1.7 2e-07 30.8 1.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78862.1 - 0.004 16.8 0.1 0.0052 16.5 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX78862.1 - 0.041 13.4 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX78862.1 - 0.058 13.1 0.2 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX78862.1 - 0.076 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX78862.1 - 0.16 11.9 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX78862.1 - 0.33 11.1 8.5 5.2 7.3 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX78863.1 - 2.2e-25 89.5 4.6 3.2e-25 89.0 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX78863.1 - 0.14 12.6 0.6 0.32 11.5 0.2 1.7 1 1 1 2 2 2 0 Cell division protein ZapB DNA_pol_B_2 PF03175.13 EAX78864.1 - 9.9e-22 77.4 3.7 1.1e-21 77.2 3.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Chal_sti_synt_N PF00195.19 EAX78865.1 - 0.092 12.2 0.2 0.17 11.3 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX78865.1 - 2.7 7.9 7.3 6.5 6.6 7.3 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX78866.1 - 1e-153 509.7 15.1 1.2e-153 509.5 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX78866.1 - 0.063 13.6 2.2 0.11 12.8 1.0 2.1 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX78866.1 - 0.19 12.3 5.8 0.66 10.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2547 PF10818.8 EAX78866.1 - 0.52 11.3 2.7 7.5 7.6 0.3 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2547) KELK PF15796.5 EAX78866.1 - 0.55 10.7 6.8 3.5 8.2 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX78866.1 - 1.6 9.1 4.4 4.2 7.7 0.0 3.1 2 2 0 2 2 2 0 Rx N-terminal domain PTR PF12789.7 EAX78867.1 - 2e-05 24.5 1.0 2e-05 24.5 1.0 4.2 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX78867.1 - 0.06 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX78867.1 - 0.069 12.9 7.8 0.13 12.0 7.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX78867.1 - 0.21 11.1 16.6 0.044 13.4 8.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX78867.1 - 1 9.8 4.1 0.91 10.0 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) MORN_2 PF07661.13 EAX78868.1 - 0.001 19.0 0.3 37 5.0 0.0 4.5 5 0 0 5 5 5 1 MORN repeat variant DUF3653 PF12375.8 EAX78868.1 - 0.024 14.7 3.7 41 4.4 0.0 4.2 4 1 0 4 4 4 0 Phage protein DUF2689 PF10894.8 EAX78868.1 - 0.059 13.1 5.5 3.2 7.6 0.1 3.8 2 2 3 5 5 5 0 Protein of unknown function (DUF2689) Pox_A32 PF04665.12 EAX78869.1 - 1.6e-07 31.0 0.8 2e-07 30.7 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78869.1 - 0.0043 16.7 0.1 0.0063 16.2 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78869.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78869.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pkinase PF00069.25 EAX78870.1 - 3.9e-51 173.9 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX78870.1 - 1.1e-13 51.1 0.0 4.8e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX78870.1 - 5e-06 26.6 0.1 0.00094 19.2 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX78870.1 - 0.0051 16.2 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAX78870.1 - 0.0052 16.4 0.1 0.35 10.5 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX78870.1 - 0.027 13.2 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF4295 PF14128.6 EAX78870.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Serendipity_A PF05482.12 EAX78870.1 - 0.21 10.2 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Trypan_PARP PF05887.11 EAX78872.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX78872.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX78873.1 - 1.1e-66 224.0 9.5 3.9e-66 222.2 9.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) YmgB PF10798.8 EAX78874.1 - 0.0032 17.2 0.1 0.0062 16.3 0.1 1.5 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR TOM13 PF08219.11 EAX78874.1 - 0.037 14.0 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein TOM13 DUF3839 PF12943.7 EAX78876.1 - 1.4e-25 90.2 4.4 2.1e-25 89.6 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX78876.1 - 0.061 13.6 0.9 0.18 12.1 0.1 2.1 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX78876.1 - 0.15 12.6 1.1 0.7 10.4 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB O-antigen_lig PF13425.6 EAX78879.1 - 1.6 7.4 3.5 2.1 7.0 3.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4108 PF13390.6 EAX78881.1 - 1.1e-57 194.0 4.4 1.2e-57 193.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX78883.1 - 1e-33 115.5 0.4 2.5e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78883.1 - 0.0011 19.1 0.4 0.0029 17.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX78883.1 - 0.037 14.5 5.0 0.19 12.2 1.2 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ycf34 PF10718.9 EAX78883.1 - 0.14 12.8 1.4 73 4.2 0.0 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3013 PF11217.8 EAX78884.1 - 0.055 13.3 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) PTR PF12789.7 EAX78886.1 - 4.3e-56 186.8 37.7 1.3e-32 111.6 17.2 5.5 4 2 1 5 5 5 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX78886.1 - 1.3 9.4 6.6 25 5.3 0.2 3.9 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain KilA-N PF04383.13 EAX78887.1 - 8.3e-10 38.5 1.3 1.9e-09 37.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX78888.1 - 9.9e-27 92.8 13.3 9.9e-27 92.8 13.3 2.2 3 0 0 3 3 3 1 Phage tail repeat like DUF4107 PF13389.6 EAX78889.1 - 2.2e-72 242.5 3.1 3.1e-72 242.0 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX78891.1 - 6.4e-244 809.7 17.2 6.4e-244 809.7 17.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX78891.1 - 0.022 15.0 0.4 1.1 9.6 0.6 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated KilA-N PF04383.13 EAX78893.1 - 5.4e-42 142.2 0.2 1.4e-41 140.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX78893.1 - 0.029 14.6 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX78894.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain Phage_fiber PF03335.13 EAX78897.1 - 5.8 7.4 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat KilA-N PF04383.13 EAX78898.1 - 2.1e-41 140.3 0.5 5.6e-41 138.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF563 PF04577.14 EAX78899.1 - 1.6e-26 93.8 0.1 2.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PapD_N PF00345.20 EAX78900.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX78900.1 - 0.064 13.2 0.6 0.094 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PadR PF03551.14 EAX78900.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_D5 PF03288.16 EAX78905.1 - 3.3e-05 24.3 2.7 0.00015 22.2 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX78905.1 - 0.038 13.1 1.1 0.054 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX78905.1 - 0.068 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX78905.1 - 0.095 12.7 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4107 PF13389.6 EAX78906.1 - 7.5e-62 208.3 12.2 4.3e-60 202.6 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78906.1 - 0.082 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX78908.1 - 1.3e-62 210.0 5.8 1.4e-62 209.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX78908.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Ank_2 PF12796.7 EAX78909.1 - 0.00084 19.9 0.0 0.25 12.0 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX78909.1 - 0.0012 18.8 3.8 0.0019 18.1 0.2 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) MGS PF02142.22 EAX78909.1 - 0.058 13.6 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain Ank_4 PF13637.6 EAX78909.1 - 0.11 13.1 0.0 2.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX78909.1 - 0.13 12.9 0.4 11 7.0 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat PTR PF12789.7 EAX78910.1 - 6.2e-10 39.0 17.2 9.3e-09 35.2 0.4 3.4 4 1 0 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX78910.1 - 0.011 15.3 2.0 0.011 15.3 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF5017 PF16409.5 EAX78910.1 - 0.21 11.1 1.8 4.2 6.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) Transposase_24 PF03004.14 EAX78910.1 - 0.36 10.9 4.5 0.38 10.9 0.9 2.2 1 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) GPS2_interact PF15784.5 EAX78911.1 - 0.049 14.1 1.4 0.068 13.6 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain T5orf172 PF10544.9 EAX78913.1 - 5.9e-07 30.0 0.3 1.1e-06 29.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX78913.1 - 0.096 13.4 0.4 0.25 12.1 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Pox_A32 PF04665.12 EAX78914.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78914.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78914.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78914.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MG2 PF01835.19 EAX78915.1 - 1.3e-06 28.7 1.9 0.018 15.5 0.1 4.0 5 0 0 5 5 4 1 MG2 domain DUF4625 PF15418.6 EAX78915.1 - 3.8e-06 27.2 1.3 0.061 13.6 0.1 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) NPCBM_assoc PF10633.9 EAX78915.1 - 0.0019 18.4 3.2 0.12 12.7 0.1 3.8 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Y_Y_Y PF07495.13 EAX78915.1 - 0.0043 17.0 0.9 0.57 10.2 0.1 3.4 3 0 0 3 3 3 1 Y_Y_Y domain ChitinaseA_N PF08329.10 EAX78915.1 - 0.0068 16.1 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Chitinase A, N-terminal domain PKD PF00801.20 EAX78915.1 - 0.011 15.5 0.9 0.81 9.6 0.0 3.6 4 1 1 5 5 5 0 PKD domain He_PIG PF05345.12 EAX78915.1 - 0.069 13.3 1.7 0.49 10.6 0.1 2.9 2 0 0 2 2 2 0 Putative Ig domain bMG6 PF17962.1 EAX78915.1 - 0.07 13.3 0.1 1.8 8.8 0.1 2.7 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 Lipocalin PF00061.23 EAX78915.1 - 0.28 11.4 5.6 0.065 13.4 1.0 2.4 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DUF4832 PF16116.5 EAX78915.1 - 0.29 11.0 2.1 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4832) RIFIN PF02009.16 EAX78915.1 - 0.32 10.9 7.4 0.62 9.9 7.4 1.5 1 0 0 1 1 1 0 Rifin BsuPI PF12690.7 EAX78915.1 - 4.2 7.4 8.3 31 4.7 0.0 4.6 6 0 0 6 6 6 0 Intracellular proteinase inhibitor DUF3839 PF12943.7 EAX78917.1 - 3.6e-83 278.7 10.9 4.6e-83 278.4 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX78917.1 - 0.079 12.5 0.8 0.49 9.9 0.0 2.3 2 1 1 3 3 3 0 SLOG cluster2 DUF2408 PF10303.9 EAX78917.1 - 0.12 12.9 1.4 0.24 11.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Amidase02_C PF12123.8 EAX78918.1 - 0.0075 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TP53IP5 PF15331.6 EAX78919.1 - 0.062 13.4 8.8 1.6 8.8 0.5 2.9 2 1 1 3 3 3 0 Cellular tumour antigen p53-inducible 5 RNA_pol_Rpc4 PF05132.14 EAX78919.1 - 0.15 12.5 0.0 2.2 8.7 0.0 2.4 3 0 0 3 3 3 0 RNA polymerase III RPC4 KilA-N PF04383.13 EAX78923.1 - 8.6e-17 61.0 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX78924.1 - 5.1e-59 199.7 3.2 5.7e-59 199.5 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78924.1 - 0.022 14.2 0.1 0.024 14.2 0.1 1.0 1 0 0 1 1 1 0 Z1 domain MvaI_BcnI PF15515.6 EAX78924.1 - 0.04 13.7 0.6 1.6 8.4 0.1 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family DUF5398 PF17376.2 EAX78924.1 - 0.15 12.7 1.6 1.4 9.6 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Amidase02_C PF12123.8 EAX78925.1 - 0.011 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78925.1 - 0.24 11.3 0.4 3.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1731) Tho2 PF11262.8 EAX78926.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Maf1 PF09174.10 EAX78928.1 - 4.8e-22 78.9 2.7 5.5e-22 78.7 2.7 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF3839 PF12943.7 EAX78929.1 - 1.3e-154 512.7 12.4 1.5e-154 512.5 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX78929.1 - 0.55 11.2 2.8 0.52 11.3 0.3 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX78929.1 - 1.2 9.6 5.9 1.9 9.0 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX78930.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAX78931.1 - 0.093 12.9 0.2 24 5.2 0.1 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain Pox_A32 PF04665.12 EAX78932.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78932.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78932.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78932.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Phage-A118_gp45 PF10653.9 EAX78933.1 - 0.12 12.4 0.1 2.6 8.1 0.0 2.4 2 1 0 2 2 2 0 Protein gp45 of Bacteriophage A118 KilA-N PF04383.13 EAX78934.1 - 1.1e-33 115.5 0.1 1.1e-33 115.5 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX78934.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX78934.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX78934.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) MULE PF10551.9 EAX78935.1 - 5.5e-12 45.9 0.1 8.7e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX78935.1 - 0.072 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 PWI domain CREPT PF16566.5 EAX78936.1 - 0.033 14.3 0.3 0.082 13.1 0.3 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AMH_N PF04709.12 EAX78936.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Fib_alpha PF08702.10 EAX78936.1 - 0.89 9.7 6.2 0.26 11.5 1.5 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KilA-N PF04383.13 EAX78938.1 - 5.5e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX78938.1 - 0.041 13.3 0.7 0.045 13.2 0.7 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX78938.1 - 0.12 11.8 0.3 0.21 11.0 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX78939.1 - 5.7e-157 520.4 12.6 6.5e-157 520.2 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78939.1 - 0.45 11.0 7.4 1.5 9.3 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX78941.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX78941.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX78941.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DNA_pol_B_2 PF03175.13 EAX78945.1 - 1.6e-29 103.1 6.4 2.8e-29 102.3 6.4 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX78945.1 - 0.025 14.7 0.6 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) JMY PF15871.5 EAX78945.1 - 0.071 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PTR PF12789.7 EAX78946.1 - 2.7e-07 30.6 35.4 3.4e-06 27.0 7.4 5.7 5 1 0 5 5 5 3 Phage tail repeat like DUF1910 PF08928.10 EAX78946.1 - 0.0089 16.0 0.5 0.78 9.7 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1910) LIFR_D2 PF17971.1 EAX78946.1 - 0.011 15.9 0.4 0.99 9.6 0.0 2.6 2 1 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX78946.1 - 1.8 8.5 4.7 23 4.9 0.1 2.7 3 0 0 3 3 3 0 Interleukin 2 XhlA PF10779.9 EAX78946.1 - 8.8 6.6 7.1 3.5 7.9 2.6 2.5 3 0 0 3 3 3 0 Haemolysin XhlA DDR PF08841.10 EAX78948.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX78948.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX78949.1 - 3e-07 30.2 2.3 3e-07 30.2 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX78949.1 - 5.6e-05 22.9 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78949.1 - 0.00016 21.7 2.7 0.0004 20.4 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX78949.1 - 0.00042 20.6 0.2 0.0033 17.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78949.1 - 0.0015 18.3 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX78949.1 - 0.0022 17.8 0.5 0.0036 17.1 0.5 1.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX78949.1 - 0.0023 17.7 0.1 0.0042 16.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX78949.1 - 0.081 13.3 0.0 0.19 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX78949.1 - 0.091 13.2 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX78949.1 - 0.21 11.9 3.1 10 6.5 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX78953.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX78953.1 - 0.071 13.1 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_MLP1_2 PF07926.12 EAX78954.1 - 0.018 15.1 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX78954.1 - 0.063 13.1 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX78954.1 - 0.44 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Spo12 PF05032.12 EAX78955.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX78956.1 - 9.4e-117 388.7 6.5 1.1e-116 388.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX78956.1 - 0.031 13.8 0.6 0.046 13.2 0.6 1.5 1 1 0 1 1 1 0 Z1 domain MetOD2 PF18548.1 EAX78957.1 - 0.015 15.4 13.1 0.05 13.7 0.7 3.6 2 1 1 3 3 3 0 Metanogen output domain 2 Exonuc_VII_L PF02601.15 EAX78957.1 - 0.031 13.9 11.5 0.066 12.8 0.2 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAX78957.1 - 0.047 12.6 24.0 0.019 13.9 4.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT20 PF14931.6 EAX78957.1 - 0.65 10.2 16.8 0.44 10.7 0.6 2.8 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Fez1 PF06818.15 EAX78957.1 - 2.1 8.8 24.3 82 3.6 14.4 2.6 1 1 1 2 2 2 0 Fez1 DivIVA PF05103.13 EAX78957.1 - 2.2 8.4 11.8 0.32 11.1 5.2 2.4 2 0 0 2 2 2 0 DivIVA protein Laminin_II PF06009.12 EAX78957.1 - 2.5 8.1 11.7 1.6 8.7 6.5 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF641 PF04859.12 EAX78957.1 - 3.2 8.1 17.0 3.8 7.9 6.4 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) NurA PF09376.10 EAX78957.1 - 4.4 6.9 10.9 0.35 10.5 2.9 2.1 1 1 1 2 2 2 0 NurA domain HR1 PF02185.16 EAX78957.1 - 5.4 7.2 16.2 0.93 9.7 8.7 3.4 3 1 0 3 3 3 0 Hr1 repeat TPR_MLP1_2 PF07926.12 EAX78957.1 - 7.6 6.6 24.9 0.035 14.2 3.3 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3839 PF12943.7 EAX78958.1 - 6.1e-154 510.5 11.9 7.2e-154 510.2 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX78958.1 - 0.077 12.9 0.7 0.26 11.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX78958.1 - 0.34 11.4 4.7 1.4 9.4 0.6 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX78960.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX78960.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX78960.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX78960.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX78961.1 - 1e-41 141.2 0.3 2.2e-41 140.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX78963.1 - 1e-156 519.5 12.9 1.3e-156 519.2 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX78963.1 - 0.13 12.7 4.1 0.84 10.1 0.6 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tho2 PF11262.8 EAX78964.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX78964.1 - 0.072 13.8 0.7 0.13 13.0 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX78964.1 - 0.39 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX78966.1 - 4.4e-157 520.7 13.3 5.5e-157 520.4 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX78966.1 - 0.14 12.6 0.3 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX78966.1 - 1.5 9.3 8.5 3.2 8.3 1.1 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX78967.1 - 4.2e-31 107.1 0.5 9.2e-31 106.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX78968.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX78968.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX78968.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX78968.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX78968.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX78968.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX78968.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX78968.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX78968.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX78968.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX78968.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX78968.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX78968.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Robl_LC7 PF03259.17 EAX78969.1 - 8.5e-12 44.7 0.0 9.3e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain PTR PF12789.7 EAX78970.1 - 4.7e-30 103.4 35.8 6.9e-09 35.6 6.2 4.6 4 0 0 4 4 4 4 Phage tail repeat like PA28_alpha PF02251.18 EAX78970.1 - 0.38 10.8 8.7 10 6.2 0.3 4.1 4 0 0 4 4 4 0 Proteasome activator pa28 alpha subunit PH_TFIIH PF08567.11 EAX78970.1 - 0.44 10.9 3.9 84 3.6 0.1 3.5 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain EMP24_GP25L PF01105.24 EAX78970.1 - 0.75 9.7 13.2 6.9 6.6 1.1 3.4 2 2 1 3 3 3 0 emp24/gp25L/p24 family/GOLD RecG_N PF17190.4 EAX78970.1 - 1.3 9.8 10.5 3.4 8.4 0.6 4.0 2 1 0 3 3 3 0 RecG N-terminal helical domain RraB PF06877.11 EAX78970.1 - 1.4 9.6 7.3 28 5.5 1.2 3.5 2 1 1 3 3 3 0 Regulator of ribonuclease activity B GUN4_N PF16416.5 EAX78970.1 - 2 8.4 7.6 7.3 6.7 0.4 3.7 2 1 1 3 3 3 0 ARM-like repeat domain, GUN4-N terminal Ferritin PF00210.24 EAX78970.1 - 2.9 7.8 8.6 11 6.0 2.0 3.0 3 0 0 3 3 3 0 Ferritin-like domain DUF4378 PF14309.6 EAX78971.1 - 0.034 14.5 0.0 0.12 12.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) T5orf172 PF10544.9 EAX78973.1 - 6.1e-06 26.7 0.3 1.4e-05 25.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX78974.1 - 3.6e-36 123.4 0.1 6.6e-36 122.6 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX78974.1 - 0.0046 17.6 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX78974.1 - 0.44 10.6 5.0 0.96 9.5 0.5 2.2 2 0 0 2 2 2 0 Tumour suppressor protein DUF4108 PF13390.6 EAX78976.1 - 4.4e-61 205.0 8.3 4.9e-61 204.8 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX78977.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain YvrJ PF12841.7 EAX78979.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family HC2 PF07382.11 EAX78980.1 - 4.7e-07 30.1 12.5 5.8e-07 29.8 12.5 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX78980.1 - 0.00013 22.1 0.4 0.00017 21.6 0.4 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Aurora-A_bind PF09041.10 EAX78980.1 - 3.2 7.9 8.1 4.1e+02 1.1 8.1 3.0 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX78980.1 - 4.9 7.2 5.3 1.8e+02 2.2 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) DUF4090 PF13319.6 EAX78982.1 - 0.0036 17.5 0.8 6.2 7.2 0.0 4.3 1 1 4 6 6 6 1 Protein of unknown function (DUF4090) DUF4717 PF15838.5 EAX78982.1 - 3 7.9 11.9 24 5.0 0.1 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4717) DUF3841 PF12952.7 EAX78982.1 - 8.7 6.1 11.0 12 5.7 0.5 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF3841) DUF4106 PF13388.6 EAX78983.1 - 7.4e-46 157.2 2.2 7.4e-46 157.2 2.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FapA PF03961.13 EAX78983.1 - 0.7 8.4 3.8 0.87 8.1 3.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CDRN PF05174.12 EAX78986.1 - 0.019 14.7 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus Prp18 PF02840.15 EAX78987.1 - 1.4e-34 119.2 2.0 5.6e-33 114.0 0.0 2.0 2 0 0 2 2 2 2 Prp18 domain PAP_central PF04928.17 EAX78987.1 - 1.2 8.0 3.8 0.86 8.5 0.1 2.1 1 1 1 2 2 2 0 Poly(A) polymerase central domain DUF4107 PF13389.6 EAX78988.1 - 9.7e-62 207.9 12.5 5.5e-60 202.2 12.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX78988.1 - 0.053 13.9 0.1 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PapD_N PF00345.20 EAX78989.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX78989.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FliJ PF02050.16 EAX78991.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein PadR PF03551.14 EAX78992.1 - 0.069 13.1 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family GPS2_interact PF15784.5 EAX78996.1 - 0.051 14.0 0.6 0.063 13.7 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX78996.1 - 0.087 11.8 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX78997.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Pox_A32 PF04665.12 EAX78998.1 - 3.2e-07 30.1 1.6 9e-07 28.6 0.1 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX78998.1 - 0.055 13.1 0.1 0.9 9.1 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX78998.1 - 0.1 12.4 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Tox-GHH PF15636.6 EAX78998.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin AAA_33 PF13671.6 EAX78998.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.8 EAX78999.1 - 0.0023 17.6 0.0 0.0065 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX78999.1 - 0.18 11.7 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX79001.1 - 8.8e-156 516.5 15.9 1.1e-155 516.2 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX79001.1 - 0.15 11.6 0.7 0.48 9.9 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 Fez1 PF06818.15 EAX79001.1 - 0.17 12.3 3.4 0.19 12.2 0.7 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX79001.1 - 0.21 11.4 2.1 0.52 10.2 0.8 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX79001.1 - 0.55 10.5 3.1 1.1 9.6 0.1 2.9 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX79001.1 - 1.2 9.6 8.5 2 9.0 0.9 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX79002.1 - 8.8e-121 401.9 11.6 1.1e-120 401.6 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79002.1 - 0.028 14.9 1.3 5.3 7.6 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX79002.1 - 0.19 11.6 1.8 0.51 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX79003.1 - 6.1e-56 189.6 3.9 7e-56 189.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MvaI_BcnI PF15515.6 EAX79003.1 - 0.071 12.9 0.7 3.3 7.5 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family DNA_pol_B_2 PF03175.13 EAX79006.1 - 1.7e-29 103.0 7.0 3.1e-29 102.2 7.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79006.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX79006.1 - 0.16 12.0 1.2 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DNA_pol_B_2 PF03175.13 EAX79007.1 - 4.7e-13 48.8 2.5 8.2e-13 48.0 2.5 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral 3-alpha PF03475.14 EAX79009.1 - 0.01 15.7 4.7 4.5 7.2 0.1 3.3 3 0 0 3 3 3 0 3-alpha domain DUF3470 PF11953.8 EAX79009.1 - 0.013 15.5 7.7 6.4 6.8 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) Spike_torovirin PF17072.5 EAX79009.1 - 0.016 12.4 1.2 1.7 5.7 0.0 2.3 3 0 0 3 3 3 0 Torovirinae spike glycoprotein DmsC PF04976.12 EAX79009.1 - 0.021 14.3 4.0 2.1 7.7 0.3 2.9 3 0 0 3 3 3 0 DMSO reductase anchor subunit (DmsC) Pkinase PF00069.25 EAX79009.1 - 0.022 14.1 0.0 21 4.3 0.0 2.9 3 0 0 3 3 3 0 Protein kinase domain DUF5488 PF17590.2 EAX79009.1 - 0.11 12.2 0.8 9.7 6.0 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5488) Pkinase PF00069.25 EAX79010.1 - 1.1e-05 24.9 0.6 14 5.0 0.0 4.8 5 0 0 5 5 5 4 Protein kinase domain 3-alpha PF03475.14 EAX79010.1 - 0.0038 17.1 13.5 22 5.0 0.1 5.5 5 0 0 5 5 5 5 3-alpha domain DUF3470 PF11953.8 EAX79010.1 - 0.051 13.6 14.3 19 5.3 0.2 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3470) PadR PF03551.14 EAX79011.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX79012.1 - 1.2e-08 34.3 2.1 1.2e-08 34.2 1.1 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79012.1 - 0.15 12.1 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor ResIII PF04851.15 EAX79013.1 - 6e-05 23.1 2.7 0.00012 22.1 2.7 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79013.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79013.1 - 0.00038 20.7 0.0 0.00064 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79013.1 - 0.00079 19.3 1.0 0.0027 17.5 1.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79013.1 - 0.007 16.7 0.0 0.0093 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79013.1 - 0.025 14.3 0.2 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX79013.1 - 0.039 13.4 0.1 0.058 12.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX79013.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79013.1 - 0.21 11.9 4.7 4.6 7.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX79015.1 - 5.1e-63 211.3 6.5 5.7e-63 211.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX79017.1 - 1.1e-271 901.2 32.8 2.1e-270 896.9 32.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX79017.1 - 0.016 15.5 0.1 0.72 10.2 0.1 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated Porin_4 PF13609.6 EAX79018.1 - 3.8e-07 30.2 1.5 4.4e-07 30.0 1.5 1.1 1 0 0 1 1 1 1 Gram-negative porin MULE PF10551.9 EAX79019.1 - 2.3e-13 50.3 0.1 4.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain MCM6_C PF18263.1 EAX79019.1 - 0.16 12.2 5.7 0.35 11.1 5.7 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain WASH-7_C PF14746.6 EAX79019.1 - 0.32 10.7 3.7 0.21 11.3 1.0 1.9 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Pox_Ag35 PF03286.14 EAX79019.1 - 1.1 9.1 5.5 1.7 8.4 5.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTR PF12789.7 EAX79020.1 - 1.2e-31 108.5 8.9 1.2e-31 108.5 8.9 4.9 4 2 2 6 6 6 1 Phage tail repeat like DUF3391 PF11871.8 EAX79020.1 - 0.022 15.3 1.4 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX79020.1 - 0.057 13.2 0.9 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX79020.1 - 8.2 6.0 21.6 0.049 13.2 4.6 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX79021.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79021.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79021.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79021.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79021.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79021.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) TPR_MLP1_2 PF07926.12 EAX79023.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX79023.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX79023.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79023.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family T5orf172 PF10544.9 EAX79024.1 - 0.00022 21.7 0.3 0.00054 20.5 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79024.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX79024.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX79024.1 - 0.034 13.7 1.6 0.32 10.5 0.5 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX79025.1 - 2.9e-78 262.7 10.0 3.8e-78 262.3 10.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79025.1 - 0.13 12.2 1.0 0.5 10.2 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX79026.1 - 1e-24 87.3 4.2 1.7e-24 86.6 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX79026.1 - 0.022 15.0 0.3 0.087 13.1 0.1 2.1 2 0 0 2 2 2 0 PRD domain T5orf172 PF10544.9 EAX79027.1 - 0.00042 20.8 0.1 0.00083 19.9 0.1 1.4 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79027.1 - 0.02 14.7 0.4 0.054 13.4 0.4 1.8 1 1 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX79028.1 - 9e-152 503.4 13.5 1e-151 503.1 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79028.1 - 0.23 11.9 4.6 1.3 9.5 0.2 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX79028.1 - 0.33 11.5 4.2 0.58 10.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX79029.1 - 7.3e-10 38.3 3.3 3.3e-09 36.1 3.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX79029.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 T5orf172 PF10544.9 EAX79030.1 - 3.9e-05 24.1 0.3 9.8e-05 22.8 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79030.1 - 0.0082 16.0 0.2 0.054 13.4 0.1 2.2 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX79030.1 - 0.033 13.7 0.7 0.13 11.7 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain Podoplanin PF05808.11 EAX79031.1 - 0.00082 19.5 2.1 0.0015 18.7 2.1 1.5 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 EAX79031.1 - 0.004 17.0 2.8 0.028 14.2 1.6 2.7 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor EGF_2 PF07974.13 EAX79031.1 - 0.031 14.7 12.5 0.031 14.7 12.5 1.7 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 EAX79031.1 - 0.069 13.5 9.1 0.14 12.5 9.1 1.5 1 0 0 1 1 1 0 EGF-like domain TMEM65 PF10507.9 EAX79031.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 65 TMEM154 PF15102.6 EAX79031.1 - 0.15 11.9 4.0 0.41 10.6 3.8 1.9 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 EAX79031.1 - 0.2 11.4 4.1 0.43 10.4 4.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4679 PF15728.5 EAX79031.1 - 1.2 8.0 7.3 1.8 7.5 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) DUF3839 PF12943.7 EAX79032.1 - 3.4e-157 521.1 15.6 3.8e-157 520.9 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79032.1 - 0.2 11.5 1.3 0.63 9.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79032.1 - 1.3 9.5 7.7 1.8 9.1 0.9 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX79034.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79034.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79034.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79034.1 - 0.00011 22.2 2.7 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79034.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79034.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79034.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79034.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX79034.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX79034.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79034.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79034.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79034.1 - 0.3 11.4 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2214 PF09980.9 EAX79035.1 - 0.088 12.6 1.9 0.097 12.5 1.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF1179 PF06678.11 EAX79035.1 - 0.13 12.2 3.3 0.089 12.8 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) DUF3592 PF12158.8 EAX79035.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) PH_10 PF15411.6 EAX79035.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain SelK_SelG PF10961.8 EAX79035.1 - 5.1 7.8 9.1 4.6 7.9 1.6 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG CLASP_N PF12348.8 EAX79037.1 - 0.0033 17.0 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal PPDFL PF15060.6 EAX79038.1 - 8.5e-05 23.0 5.2 3.9 8.0 0.2 3.7 3 0 0 3 3 3 3 Differentiation and proliferation regulator TQ PF18202.1 EAX79038.1 - 0.0022 18.5 32.1 0.71 10.4 4.1 4.2 2 1 2 4 4 4 3 T-Q ester bond containing domain Chordopox_G3 PF06129.12 EAX79038.1 - 0.0059 17.3 8.3 12 6.7 0.1 3.8 4 0 0 4 4 4 0 Chordopoxvirus G3 protein AMP-binding_C_2 PF14535.6 EAX79038.1 - 0.0086 16.4 0.2 60 4.0 0.0 3.6 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain DUF2011 PF09428.10 EAX79038.1 - 0.011 15.9 8.6 9.9 6.5 0.2 3.6 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2011) Arm-DNA-bind_4 PF14657.6 EAX79038.1 - 0.014 15.2 0.0 60 3.5 0.0 3.6 3 0 0 3 3 3 0 Arm DNA-binding domain ETC_C1_NDUFA4 PF04800.12 EAX79038.1 - 0.045 14.0 1.2 79 3.6 0.0 3.5 3 0 0 3 3 3 0 ETC complex I subunit conserved region DUF3416 PF11896.8 EAX79038.1 - 0.048 13.9 1.6 58 3.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3416) PhoD_N PF16655.5 EAX79038.1 - 0.053 14.1 12.1 3.4 8.3 0.2 4.8 3 1 2 5 5 5 0 PhoD-like phosphatase, N-terminal domain DUF2536 PF10750.9 EAX79038.1 - 0.064 13.2 0.8 19 5.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) THF_DHG_CYH PF00763.23 EAX79038.1 - 0.11 12.7 2.4 1.4e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CBM60 PF16841.5 EAX79038.1 - 0.75 10.3 12.3 19 5.7 0.4 3.6 3 0 0 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding BAT PF15915.5 EAX79038.1 - 1.2 9.0 4.0 1e+02 2.8 0.1 3.2 3 0 0 3 3 3 0 GAF and HTH_10 associated domain HYR PF02494.16 EAX79038.1 - 1.4 9.3 11.3 13 6.2 0.7 3.5 3 0 0 3 3 3 0 HYR domain Adap_comp_sub PF00928.21 EAX79038.1 - 1.9 7.8 13.7 5.8 6.2 0.6 3.4 2 1 1 4 4 4 0 Adaptor complexes medium subunit family PQQ PF01011.21 EAX79038.1 - 5.4 7.1 8.5 92 3.2 0.2 4.1 3 0 0 3 3 3 0 PQQ enzyme repeat PTR PF12789.7 EAX79039.1 - 4.9e-24 84.1 7.3 4.9e-24 84.1 7.3 3.4 2 1 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX79039.1 - 0.022 14.5 0.1 0.074 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX79039.1 - 0.44 10.5 7.8 0.92 9.4 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF3839 PF12943.7 EAX79040.1 - 2.1e-147 489.1 14.4 2.6e-147 488.8 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79040.1 - 0.098 13.1 2.2 0.21 12.0 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX79040.1 - 0.27 11.7 5.5 1.8 9.1 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79041.1 - 1.7e-10 40.7 0.8 4.4e-10 39.4 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX79042.1 - 1.3e-148 493.0 13.5 1.7e-148 492.7 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX79042.1 - 0.086 13.2 1.0 0.27 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) NTP_transf_6 PF06042.11 EAX79042.1 - 0.13 12.1 0.6 0.39 10.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79042.1 - 0.82 10.2 4.1 1.9 9.0 0.6 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MULE PF10551.9 EAX79043.1 - 7.5e-11 42.3 1.5 1.1e-10 41.7 1.5 1.2 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX79043.1 - 0.0017 18.4 2.2 0.0049 16.9 2.2 1.7 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Na_H_antiporter PF03553.14 EAX79043.1 - 0.13 11.4 0.3 0.17 11.1 0.3 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter family DUF3839 PF12943.7 EAX79044.1 - 1.2e-16 60.9 3.4 2e-16 60.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX79044.1 - 0.12 12.8 1.0 0.55 10.7 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF3839 PF12943.7 EAX79045.1 - 3.6e-125 416.3 6.4 4.1e-125 416.1 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX79045.1 - 0.043 14.1 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAX79045.1 - 0.26 11.9 2.0 0.55 10.9 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX79046.1 - 2.9e-156 518.0 13.4 3.7e-156 517.7 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79046.1 - 0.028 14.9 1.9 0.082 13.4 0.4 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX79046.1 - 0.59 10.6 6.4 2.3 8.8 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX79046.1 - 0.68 10.5 6.4 0.18 12.3 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX79048.1 - 1.6e-59 200.0 8.9 1.8e-59 199.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79049.1 - 3.5e-05 24.2 4.0 0.00027 21.4 4.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79049.1 - 0.044 14.4 0.1 0.08 13.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79049.1 - 0.051 13.6 0.2 0.077 13.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain VirE PF05272.11 EAX79050.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX79050.1 - 0.053 13.9 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 EAX79050.1 - 0.28 10.6 0.1 0.28 10.6 0.1 2.4 1 1 1 2 2 2 0 Poxvirus A32 protein PTR PF12789.7 EAX79051.1 - 5.6e-13 48.7 24.0 1.2e-08 34.9 5.2 4.6 5 0 0 5 5 5 3 Phage tail repeat like EpuA PF11772.8 EAX79051.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta CH PF00307.31 EAX79052.1 - 0.11 12.6 0.0 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF2939 PF11159.8 EAX79053.1 - 0.083 13.3 0.2 0.1 13.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Tctex-1 PF03645.13 EAX79053.1 - 0.11 12.7 0.3 0.16 12.2 0.3 1.3 1 0 0 1 1 1 0 Tctex-1 family PadR PF03551.14 EAX79054.1 - 0.082 12.9 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX79055.1 - 4.3e-48 162.9 8.2 4.7e-48 162.7 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX79056.1 - 0.067 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX79056.1 - 0.11 12.7 10.5 0.16 12.3 10.5 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX79057.1 - 1.1e-59 200.4 8.5 1.3e-59 200.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79058.1 - 8.4e-41 140.0 4.3 1.2e-40 139.6 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX79059.1 - 1e-152 506.5 12.3 1.2e-152 506.2 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79059.1 - 0.092 13.2 3.2 1.4 9.4 0.2 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX79060.1 - 3e-57 193.3 11.3 1.8e-55 187.5 11.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79060.1 - 0.1 13.0 0.5 0.14 12.6 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX79061.1 - 5.3e-15 55.3 1.6 6.7e-15 54.9 1.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX79062.1 - 1.8e-08 33.7 1.5 1.2e-07 31.0 1.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX79062.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX79063.1 - 2.6e-155 515.0 14.1 3.2e-155 514.6 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX79063.1 - 0.15 12.6 5.5 0.55 10.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5398 PF17376.2 EAX79063.1 - 0.37 11.4 4.3 0.54 10.9 0.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX79063.1 - 0.5 10.8 5.6 3.5 8.1 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX79064.1 - 4.1e-25 88.6 3.6 6.1e-25 88.1 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX79064.1 - 0.028 14.7 0.7 0.081 13.2 0.1 1.9 1 1 1 2 2 2 0 PRD domain DUF3839 PF12943.7 EAX79065.1 - 3.6e-154 511.2 15.1 4.3e-154 511.0 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79065.1 - 0.26 11.6 5.0 0.38 11.1 0.1 3.1 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX79065.1 - 0.43 11.1 6.1 4.5 7.8 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX79065.1 - 0.77 10.3 5.2 0.76 10.3 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF563 PF04577.14 EAX79066.1 - 4.9e-31 108.5 0.6 7.1e-31 108.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3839 PF12943.7 EAX79067.1 - 5e-102 340.5 7.7 5.6e-102 340.3 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX79068.1 - 5e-10 39.2 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX79069.1 - 2e-149 495.7 13.9 2.4e-149 495.4 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79069.1 - 0.16 12.4 5.5 4.5 7.8 0.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX79069.1 - 2.1 8.9 5.5 1 9.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) rve PF00665.26 EAX79071.1 - 8.4e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EAX79071.1 - 0.0072 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Sugar_tr PF00083.24 EAX79072.1 - 1.8e-55 188.7 23.0 1.2e-54 185.9 23.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX79072.1 - 7.8e-28 97.4 46.1 8.1e-22 77.6 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX79072.1 - 5.9e-09 35.0 14.7 0.0001 21.0 2.5 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein VIT1 PF01988.19 EAX79072.1 - 0.73 9.7 11.3 0.83 9.5 0.0 3.1 2 1 1 3 3 3 0 VIT family DUF3839 PF12943.7 EAX79074.1 - 3e-157 521.3 14.5 3.7e-157 521.0 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79074.1 - 0.11 12.7 0.4 2.5 8.5 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX79074.1 - 0.68 10.4 7.6 2.3 8.8 0.7 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79075.1 - 1.4e-26 92.6 0.6 2.9e-26 91.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79075.1 - 0.081 13.5 0.0 0.23 12.1 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX79075.1 - 0.27 12.0 1.3 13 6.5 0.2 2.9 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3839 PF12943.7 EAX79077.1 - 3.2e-148 491.7 11.1 3.7e-148 491.5 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79077.1 - 0.039 13.8 0.8 0.15 11.9 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX79078.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX79079.1 - 8.9e-29 100.6 6.2 1.5e-28 99.9 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX79079.1 - 0.049 13.9 0.7 0.12 12.6 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX79079.1 - 0.13 12.7 0.5 0.29 11.6 0.3 1.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF3839 PF12943.7 EAX79080.1 - 2.4e-156 518.4 13.3 3e-156 518.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79080.1 - 0.17 11.7 1.5 0.5 10.2 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX79080.1 - 1.2 9.5 4.0 4.3 7.7 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain Glu-tRNAGln PF02686.15 EAX79080.1 - 1.6 9.1 4.3 0.96 9.8 1.1 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX79080.1 - 4.6 7.8 7.0 4.6 7.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ANAPC4_WD40 PF12894.7 EAX79081.1 - 0.0027 18.0 0.0 6.5 7.1 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain FliJ PF02050.16 EAX79082.1 - 0.022 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1493 PF07377.12 EAX79083.1 - 0.061 13.8 0.4 0.12 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX79084.1 - 5.6e-39 132.0 25.2 5.5e-33 112.8 12.9 4.4 3 2 2 5 5 5 2 Phage tail repeat like DUF3391 PF11871.8 EAX79084.1 - 0.3 11.6 3.0 10 6.7 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Pox_A32 PF04665.12 EAX79088.1 - 9.5e-05 22.0 3.7 0.00017 21.1 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX79088.1 - 0.0061 16.6 0.8 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX79088.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4108 PF13390.6 EAX79090.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79091.1 - 0.0001 22.7 2.3 0.00066 20.1 2.3 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79091.1 - 0.038 14.6 0.1 0.078 13.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79091.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DNA_pol_B_2 PF03175.13 EAX79092.1 - 4.5e-28 98.3 6.7 7.5e-28 97.6 6.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79092.1 - 0.054 12.8 0.3 0.085 12.1 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX79092.1 - 0.092 12.8 4.3 1.4 9.0 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5065) ANAPC4_WD40 PF12894.7 EAX79093.1 - 0.0011 19.3 0.0 3.9 7.8 0.0 3.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain MMtag PF10159.9 EAX79093.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated KilA-N PF04383.13 EAX79094.1 - 4e-23 81.4 1.6 5.1e-23 81.1 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79094.1 - 0.0028 18.3 0.1 0.009 16.6 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX79095.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX79095.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DDR PF08841.10 EAX79096.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX79096.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX79098.1 - 1e-118 395.1 12.1 1.3e-118 394.8 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79098.1 - 0.048 14.1 2.2 5.3 7.6 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX79098.1 - 0.24 11.2 1.8 0.62 9.9 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PadR PF03551.14 EAX79100.1 - 0.078 12.9 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DNA_pol3_a_NII PF11490.8 EAX79100.1 - 0.72 9.8 6.1 0.14 12.0 0.9 2.0 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II DDE_Tnp_ISL3 PF01610.17 EAX79101.1 - 2.9e-05 23.9 0.2 5.5e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Transposase DUF3839 PF12943.7 EAX79102.1 - 7.8e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DDR PF08841.10 EAX79104.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX79104.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain LRR_5 PF13306.6 EAX79106.1 - 2.7e-52 176.1 49.6 2.9e-23 82.2 12.7 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX79106.1 - 8.6e-10 38.2 15.0 0.0086 15.8 0.1 7.3 3 3 6 9 9 9 4 Leucine rich repeat LRR_4 PF12799.7 EAX79106.1 - 0.00054 20.3 27.7 0.15 12.5 0.2 6.8 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF3781 PF12636.7 EAX79107.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DNA_pol_B_2 PF03175.13 EAX79108.1 - 1.7e-30 106.3 12.6 9e-30 103.9 12.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX79109.1 - 6.5e-31 107.7 13.6 2.9e-30 105.6 13.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79109.1 - 0.021 14.2 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein GPS2_interact PF15784.5 EAX79112.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX79113.1 - 2.1e-07 30.7 1.8 2.9e-07 30.2 1.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79113.1 - 0.0057 16.3 0.1 0.0074 16.0 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79113.1 - 0.07 12.6 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF3783 PF12646.7 EAX79113.1 - 0.076 13.0 0.8 1.3 9.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX79113.1 - 0.096 12.4 0.1 0.26 11.0 0.0 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3839 PF12943.7 EAX79114.1 - 8.4e-06 25.4 1.0 1.5e-05 24.6 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX79116.1 - 3.1e-149 485.9 13.6 1.8e-21 76.5 0.1 7.0 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX79116.1 - 2.4e-88 289.4 0.8 1.5e-12 47.8 0.0 8.5 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX79116.1 - 4.5e-83 272.2 7.5 2.3e-10 40.5 0.0 10.6 2 1 9 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX79116.1 - 4.6e-82 267.2 0.1 1.3e-06 28.6 0.0 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 EAX79116.1 - 4.6e-70 223.2 0.0 2e-05 24.6 0.0 11.6 11 0 0 11 11 11 11 Ankyrin repeat PilZ_2 PF16823.5 EAX79116.1 - 3.4e-05 24.0 0.0 1.3 9.2 0.0 3.9 1 1 3 5 5 4 1 Atypical PilZ domain, cyclic di-GMP receptor DUF2795 PF11387.8 EAX79116.1 - 0.00037 20.7 9.2 96 3.3 0.0 9.1 10 0 0 10 10 10 0 Protein of unknown function (DUF2795) APG6_N PF17675.1 EAX79116.1 - 0.0028 18.2 10.2 0.0053 17.3 10.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc29 PF17082.5 EAX79116.1 - 0.0029 17.5 4.1 0.0046 16.8 4.1 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 FapA PF03961.13 EAX79116.1 - 0.0049 15.5 6.2 0.0049 15.5 6.2 1.6 2 0 0 2 2 2 1 Flagellar Assembly Protein A Spc7 PF08317.11 EAX79116.1 - 0.0069 15.3 7.2 0.01 14.8 7.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Wtap PF17098.5 EAX79116.1 - 0.009 15.9 5.8 0.016 15.1 5.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family Pox_E8 PF03394.13 EAX79116.1 - 0.017 14.7 6.7 48 3.4 0.1 6.9 4 2 6 10 10 10 0 Poxvirus E8 protein ATG16 PF08614.11 EAX79116.1 - 0.02 15.1 6.8 0.031 14.5 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 EAX79116.1 - 0.026 15.2 2.4 0.053 14.2 2.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) GBP_C PF02841.14 EAX79116.1 - 0.043 13.2 7.4 0.067 12.6 7.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF812 PF05667.11 EAX79116.1 - 0.051 12.5 8.2 0.074 11.9 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WXG100 PF06013.12 EAX79116.1 - 0.055 13.7 1.2 0.12 12.6 1.2 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG ABC_tran_CTD PF16326.5 EAX79116.1 - 0.065 13.5 6.9 0.13 12.5 6.9 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Muted PF14942.6 EAX79116.1 - 0.07 13.5 8.9 0.13 12.6 8.9 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Golgin_A5 PF09787.9 EAX79116.1 - 0.076 12.5 8.2 0.11 11.9 8.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 FliJ PF02050.16 EAX79116.1 - 0.077 13.2 8.4 0.1 12.9 5.5 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein OmpH PF03938.14 EAX79116.1 - 0.077 13.3 7.7 0.14 12.5 7.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Het-C PF07217.11 EAX79116.1 - 0.088 11.3 4.0 0.12 10.9 4.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Fmp27_WPPW PF10359.9 EAX79116.1 - 0.096 11.5 6.3 0.14 10.9 6.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ketoacyl-synt_2 PF13723.6 EAX79116.1 - 0.24 11.0 0.8 57 3.2 0.0 4.0 3 1 1 4 4 3 0 Beta-ketoacyl synthase, N-terminal domain COG2 PF06148.11 EAX79116.1 - 0.25 11.5 5.7 0.18 11.9 3.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2730 PF10805.8 EAX79116.1 - 0.27 11.4 2.3 0.65 10.1 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) AAA_32 PF13654.6 EAX79116.1 - 0.29 9.9 6.2 0.45 9.3 6.2 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EAX79116.1 - 0.3 11.1 4.5 0.56 10.3 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EAX79116.1 - 0.39 10.9 10.4 0.35 11.1 7.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Allexi_40kDa PF05549.11 EAX79116.1 - 0.52 9.8 3.4 0.8 9.2 3.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMPIT PF07851.13 EAX79116.1 - 0.52 9.5 5.5 0.79 8.9 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein ACCA PF03255.14 EAX79116.1 - 0.54 10.1 3.8 1.1 9.2 3.8 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit V_ATPase_I PF01496.19 EAX79116.1 - 0.58 8.0 4.9 0.74 7.7 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 5_nucleotid PF05761.14 EAX79116.1 - 0.64 8.9 4.3 0.98 8.2 4.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family GIT1_C PF12205.8 EAX79116.1 - 0.75 9.9 4.8 1.4 9.1 4.6 1.5 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Lectin_N PF03954.14 EAX79116.1 - 0.81 9.4 5.2 1.6 8.5 5.2 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 EAX79116.1 - 0.97 8.7 2.9 1.5 8.1 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EAX79116.1 - 1.1 9.5 13.2 4 7.7 11.7 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 EAX79116.1 - 1.3 9.0 10.7 0.53 10.2 5.7 2.5 1 1 1 2 2 2 0 Prefoldin subunit Swi5 PF07061.11 EAX79116.1 - 1.3 9.1 13.2 0.4 10.8 7.9 2.3 1 1 1 2 2 2 0 Swi5 Bap31_Bap29_C PF18035.1 EAX79116.1 - 1.4 9.0 8.2 3.9 7.6 8.2 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 EAX79116.1 - 1.6 7.8 8.5 2.2 7.3 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 EAX79116.1 - 1.7 9.0 4.5 2.7 8.3 2.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.18 EAX79116.1 - 1.9 8.3 5.8 3.4 7.5 5.8 1.4 1 0 0 1 1 1 0 PCRF domain CCDC-167 PF15188.6 EAX79116.1 - 2 8.8 7.9 4.9 7.6 7.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 EAX79116.1 - 2.7 8.5 8.5 9.1 6.8 7.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GTP-bdg_M PF16360.5 EAX79116.1 - 4.1 8.1 4.7 20 5.9 0.7 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF349 PF03993.12 EAX79116.1 - 4.6 7.6 6.9 14 6.1 3.6 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1640 PF07798.11 EAX79116.1 - 5.6 7.0 10.4 10 6.1 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YtxH PF12732.7 EAX79116.1 - 7.5 7.2 6.8 3.4 8.2 2.8 2.4 1 1 1 2 2 2 0 YtxH-like protein TPR_MLP1_2 PF07926.12 EAX79118.1 - 0.035 14.2 0.2 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX79118.1 - 0.085 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79118.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX79120.1 - 1.6e-41 140.6 0.5 3.3e-41 139.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79120.1 - 0.014 16.0 0.0 0.045 14.4 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF4107 PF13389.6 EAX79121.1 - 4.9e-30 104.8 4.5 4.5e-28 98.4 4.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX79122.1 - 2.6e-21 76.4 1.7 2.9e-21 76.3 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX79124.1 - 7.7e-10 38.2 3.0 4.1e-09 35.8 3.0 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX79124.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX79126.1 - 7.6e-26 91.0 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX79126.1 - 0.057 13.7 0.4 0.18 12.1 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX79126.1 - 0.096 13.1 1.2 0.37 11.2 0.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX79127.1 - 1.3e-41 140.9 0.1 2.3e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX79128.1 - 5.2e-06 27.0 0.2 1e-05 26.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79129.1 - 9e-40 135.0 0.8 1.5e-39 134.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain ABC1 PF03109.16 EAX79129.1 - 0.0038 17.4 0.7 0.97 9.6 0.1 2.7 1 1 1 2 2 2 2 ABC1 family Parathyroid PF01279.17 EAX79129.1 - 0.015 15.9 0.0 0.051 14.2 0.0 1.9 1 0 0 1 1 1 0 Parathyroid hormone family Amidase02_C PF12123.8 EAX79130.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX79131.1 - 5.8e-07 30.0 1.0 1.5e-06 28.7 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX79131.1 - 0.034 13.7 0.7 0.4 10.2 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4107 PF13389.6 EAX79132.1 - 2.7e-71 239.0 3.9 3.6e-71 238.6 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX79133.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX79134.1 - 0.028 14.9 0.6 0.05 14.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX79135.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79135.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79135.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79135.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX79136.1 - 1.6e-18 66.5 1.8 1.9e-18 66.3 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79136.1 - 0.013 16.1 0.0 0.027 15.1 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family PTR PF12789.7 EAX79137.1 - 1.3e-33 114.8 26.7 1.1e-25 89.4 13.7 4.7 5 1 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX79137.1 - 0.03 14.0 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX79137.1 - 1.1 9.9 18.5 1.2 9.8 0.3 4.3 3 2 0 4 4 4 0 YmaF family DUF3839 PF12943.7 EAX79139.1 - 1.1e-47 162.6 2.3 1.2e-47 162.4 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4795 PF16043.5 EAX79141.1 - 2.5e-05 24.0 5.4 0.0091 15.6 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) Cyclin_C_2 PF16899.5 EAX79141.1 - 0.018 15.4 0.3 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain PTR PF12789.7 EAX79141.1 - 0.028 14.5 6.3 0.36 10.9 1.5 3.4 2 2 0 2 2 2 0 Phage tail repeat like DUF826 PF05696.11 EAX79141.1 - 0.11 12.6 0.7 2.6 8.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF826) DUF4106 PF13388.6 EAX79142.1 - 3.6e-275 912.6 18.7 3.6e-275 912.6 18.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX79142.1 - 0.023 15.0 0.1 1.1 9.6 0.2 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated TPR_MLP1_2 PF07926.12 EAX79143.1 - 0.018 15.1 0.3 0.023 14.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX79143.1 - 0.063 13.1 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79143.1 - 0.47 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX79144.1 - 4.8e-05 23.0 2.1 4.8e-05 23.0 2.1 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX79144.1 - 0.004 17.2 0.1 0.0094 16.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX79144.1 - 0.017 14.7 0.2 0.034 13.7 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX79144.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PTR PF12789.7 EAX79145.1 - 8.4e-111 362.1 74.9 5.7e-31 106.4 13.4 6.7 2 2 4 6 6 6 5 Phage tail repeat like PH_TFIIH PF08567.11 EAX79145.1 - 0.12 12.7 19.2 26 5.2 0.3 7.6 1 1 7 8 8 8 0 TFIIH p62 subunit, N-terminal domain AviRa PF11599.8 EAX79145.1 - 0.24 10.8 7.7 0.77 9.2 0.6 3.1 1 1 2 3 3 3 0 RRNA methyltransferase AviRa DUF1493 PF07377.12 EAX79146.1 - 0.011 16.2 0.3 0.018 15.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX79149.1 - 3e-157 521.3 13.1 3.8e-157 521.0 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79149.1 - 0.16 11.9 1.0 0.46 10.3 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX79150.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79150.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79150.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79150.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79150.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79150.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF2897 PF11446.8 EAX79152.1 - 0.97 9.4 3.0 2.2 8.2 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79153.1 - 7.1e-54 181.6 8.0 7.9e-54 181.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX79157.1 - 1.8e-40 137.2 1.8 2.4e-40 136.9 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79157.1 - 0.013 15.7 0.7 0.036 14.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) KilA-N PF04383.13 EAX79159.1 - 2.4e-44 149.8 0.7 5.9e-44 148.5 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DUF5446 PF17522.2 EAX79160.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Amidase02_C PF12123.8 EAX79161.1 - 0.0033 17.1 0.1 0.009 15.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX79162.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79162.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79162.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79162.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79162.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79162.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79162.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX79163.1 - 2.3e-11 43.5 0.5 6.5e-11 42.1 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF4108 PF13390.6 EAX79164.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79167.1 - 6.6e-05 23.3 3.8 0.00049 20.5 3.8 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79167.1 - 0.017 15.7 0.2 0.033 14.8 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PTR PF12789.7 EAX79168.1 - 3.1e-05 23.9 0.6 3.1e-05 23.9 0.6 3.7 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX79168.1 - 0.019 14.7 0.3 0.093 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX79168.1 - 0.096 11.6 0.6 0.17 10.9 0.6 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX79168.1 - 0.12 12.2 9.0 0.18 11.6 9.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX79168.1 - 0.22 12.0 4.6 0.26 11.8 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) PTR PF12789.7 EAX79169.1 - 5.6e-23 80.8 21.4 2.6e-16 59.4 2.5 4.6 6 0 0 6 6 6 2 Phage tail repeat like Peptidase_C78 PF07910.13 EAX79169.1 - 0.04 13.4 0.4 5.1 6.5 0.0 2.4 1 1 1 2 2 2 0 Peptidase family C78 YmaF PF12788.7 EAX79169.1 - 3.5 8.2 19.3 2 9.0 2.7 4.1 2 2 0 2 2 2 0 YmaF family DUF2897 PF11446.8 EAX79172.1 - 0.74 9.7 3.9 0.98 9.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79173.1 - 1.2e-61 206.8 7.3 1.3e-61 206.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79174.1 - 0.00016 22.1 4.0 0.0011 19.4 4.0 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX79174.1 - 0.032 13.3 1.1 0.045 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) KilA-N PF04383.13 EAX79175.1 - 2.6e-17 62.7 0.0 5.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain GGDEF PF00990.21 EAX79176.1 - 0.044 13.5 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX79177.1 - 2e-60 202.9 7.4 2.2e-60 202.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX79178.1 - 0.0074 16.0 0.1 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX79179.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX79180.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX79181.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX79181.1 - 0.12 12.3 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FAS_N PF17828.1 EAX79182.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX79183.1 - 0.024 15.0 0.3 0.032 14.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX79183.1 - 2 8.4 4.6 2.2 8.3 4.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX79184.1 - 0.0081 16.1 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Ank_2 PF12796.7 EAX79185.1 - 3.1e-66 220.0 3.3 1.2e-15 57.8 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX79185.1 - 6.5e-43 143.4 0.0 1.8e-06 28.1 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX79185.1 - 7.9e-42 140.8 0.5 7e-11 42.2 0.1 5.9 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX79185.1 - 3.4e-40 135.9 0.0 1.3e-11 44.7 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX79185.1 - 2.2e-35 116.7 0.0 1.4e-05 25.1 0.0 6.8 7 0 0 7 7 6 6 Ankyrin repeat Spc29 PF17082.5 EAX79185.1 - 0.0019 18.1 4.4 0.0028 17.5 4.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 APG6_N PF17675.1 EAX79185.1 - 0.002 18.7 10.7 0.0038 17.7 10.7 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 EAX79185.1 - 0.0029 16.3 6.4 0.0029 16.3 6.4 1.8 2 0 0 2 2 2 1 Flagellar Assembly Protein A Spc7 PF08317.11 EAX79185.1 - 0.004 16.1 7.4 0.0057 15.6 7.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein L_protein_N PF15518.6 EAX79185.1 - 0.0045 16.8 0.0 5.9 6.8 0.0 4.0 2 1 2 4 4 4 0 L protein N-terminus Wtap PF17098.5 EAX79185.1 - 0.0052 16.7 5.8 0.0094 15.9 5.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family DUF2203 PF09969.9 EAX79185.1 - 0.0085 16.8 1.8 0.018 15.8 1.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 EAX79185.1 - 0.01 16.1 5.1 0.055 13.7 5.5 2.0 2 0 0 2 2 1 1 Flagellar FliJ protein ATG16 PF08614.11 EAX79185.1 - 0.011 15.9 6.8 0.017 15.3 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GBP_C PF02841.14 EAX79185.1 - 0.018 14.5 7.0 0.026 13.9 7.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TerB_C PF15615.6 EAX79185.1 - 0.023 15.0 3.6 0.053 13.8 3.5 1.7 2 0 0 2 2 1 0 TerB-C domain Muted PF14942.6 EAX79185.1 - 0.031 14.6 8.5 0.054 13.8 8.5 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Het-C PF07217.11 EAX79185.1 - 0.035 12.7 3.5 0.045 12.3 3.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ABC_tran_CTD PF16326.5 EAX79185.1 - 0.035 14.4 6.9 0.078 13.2 6.9 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF812 PF05667.11 EAX79185.1 - 0.044 12.7 8.9 0.06 12.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fmp27_WPPW PF10359.9 EAX79185.1 - 0.05 12.5 6.3 0.072 11.9 6.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain OmpH PF03938.14 EAX79185.1 - 0.06 13.7 8.2 0.11 12.9 8.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 EAX79185.1 - 0.066 12.7 8.9 0.095 12.1 8.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 WXG100 PF06013.12 EAX79185.1 - 0.095 12.9 2.9 0.23 11.7 2.9 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG COG2 PF06148.11 EAX79185.1 - 0.12 12.4 5.9 0.11 12.6 3.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_32 PF13654.6 EAX79185.1 - 0.14 10.9 6.1 0.22 10.3 6.1 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EAX79185.1 - 0.17 11.9 4.5 0.32 11.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RapA_C PF12137.8 EAX79185.1 - 0.17 10.8 4.4 0.26 10.3 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal TMPIT PF07851.13 EAX79185.1 - 0.21 10.8 5.1 0.3 10.3 5.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.8 EAX79185.1 - 0.23 11.7 11.0 0.29 11.4 8.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YlqD PF11068.8 EAX79185.1 - 0.24 11.8 7.8 0.42 11.0 7.8 1.4 1 0 0 1 1 1 0 YlqD protein ACCA PF03255.14 EAX79185.1 - 0.26 11.2 3.7 0.54 10.1 3.7 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Allexi_40kDa PF05549.11 EAX79185.1 - 0.28 10.7 3.4 0.41 10.1 3.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein 5_nucleotid PF05761.14 EAX79185.1 - 0.37 9.6 4.4 0.54 9.1 4.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family V_ATPase_I PF01496.19 EAX79185.1 - 0.38 8.6 5.2 0.44 8.4 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT1_C PF12205.8 EAX79185.1 - 0.43 10.7 5.0 0.65 10.1 4.5 1.6 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4407 PF14362.6 EAX79185.1 - 0.49 9.7 2.8 0.73 9.1 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 EAX79185.1 - 0.51 10.1 5.4 0.95 9.2 5.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2730 PF10805.8 EAX79185.1 - 0.59 10.3 4.2 1.2 9.3 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Spc24 PF08286.11 EAX79185.1 - 0.63 10.3 13.7 0.46 10.8 8.8 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 EAX79185.1 - 0.73 10.0 13.6 0.25 11.4 8.0 2.4 1 1 1 2 2 2 0 Swi5 Prefoldin PF02996.17 EAX79185.1 - 0.82 9.6 11.8 0.22 11.4 5.1 2.8 1 1 1 2 2 2 0 Prefoldin subunit PCRF PF03462.18 EAX79185.1 - 0.95 9.3 5.7 1.6 8.6 5.7 1.3 1 0 0 1 1 1 0 PCRF domain DUF948 PF06103.11 EAX79185.1 - 1 9.7 4.7 4.6 7.6 4.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 EAX79185.1 - 1 8.4 8.8 1.4 8.0 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 EAX79185.1 - 1 10.1 7.0 1.3 9.8 2.8 2.3 1 1 1 2 2 2 0 Occludin homology domain NPV_P10 PF05531.12 EAX79185.1 - 1.1 9.8 8.6 7.7 7.1 8.4 2.3 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein Rx_N PF18052.1 EAX79185.1 - 1.4 9.3 5.6 16 5.9 0.1 2.6 1 1 1 2 2 2 0 Rx N-terminal domain Tho2 PF11262.8 EAX79185.1 - 1.4 8.1 8.2 2.2 7.4 8.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF349 PF03993.12 EAX79185.1 - 1.5 9.2 6.8 8.3 6.8 3.6 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) GTP-bdg_M PF16360.5 EAX79185.1 - 1.6 9.4 4.7 12 6.5 0.7 2.6 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Laminin_II PF06009.12 EAX79185.1 - 3.1 7.8 10.9 0.71 9.9 7.1 1.9 2 0 0 2 2 2 0 Laminin Domain II DUF1640 PF07798.11 EAX79185.1 - 3.2 7.8 10.5 5.8 6.9 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YtxH PF12732.7 EAX79185.1 - 4.2 8.0 7.3 44 4.7 7.3 2.5 1 1 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.6 EAX79185.1 - 4.8 7.3 5.9 8.6 6.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31_Bap29_C PF18035.1 EAX79185.1 - 5.1 7.2 10.9 7.3 6.7 9.9 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CCDC-167 PF15188.6 EAX79185.1 - 5.8 7.3 10.3 2.1 8.7 7.5 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 EAX79185.1 - 6.7 5.5 5.1 9.4 5.0 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S64 PF08192.11 EAX79186.1 - 3.6 6.0 25.7 4.2 5.7 25.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3839 PF12943.7 EAX79187.1 - 7.5e-155 513.4 11.8 9.4e-155 513.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79187.1 - 0.099 12.5 0.7 0.28 11.0 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX79187.1 - 0.52 10.6 4.8 2 8.8 0.0 3.4 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX79187.1 - 0.83 10.1 5.5 3.8 8.0 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX79189.1 - 2.9e-06 27.8 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79189.1 - 0.0071 16.2 0.1 0.035 14.0 0.1 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX79189.1 - 0.01 15.4 1.0 0.1 12.1 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain PapD_N PF00345.20 EAX79191.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79191.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX79192.1 - 6.1e-10 39.0 8.4 2.9e-09 36.8 2.0 5.4 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX79192.1 - 0.0032 17.1 15.8 0.045 13.4 2.9 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Cas_Csm6 PF09659.10 EAX79192.1 - 0.004 16.0 0.4 0.0065 15.3 0.2 1.4 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) CppA_C PF14507.6 EAX79192.1 - 0.059 14.1 0.5 0.059 14.1 0.5 2.1 3 0 0 3 3 3 0 CppA C-terminal YmaF PF12788.7 EAX79192.1 - 2.9 8.5 11.1 27 5.4 0.1 3.8 3 1 0 3 3 3 0 YmaF family DUF4108 PF13390.6 EAX79193.1 - 5.1e-61 204.8 9.3 5.7e-61 204.6 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX79194.1 - 1.3 8.8 3.0 0.99 9.1 1.8 1.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF3839 PF12943.7 EAX79195.1 - 1e-149 496.6 14.2 1.3e-149 496.3 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79195.1 - 0.14 12.6 6.7 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX79195.1 - 3.8 8.1 6.5 1.2 9.7 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX79195.1 - 6.6 7.1 7.7 13 6.1 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal Pox_A32 PF04665.12 EAX79196.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX79196.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase PTR PF12789.7 EAX79198.1 - 2e-08 34.2 2.1 2e-08 34.2 2.1 4.2 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX79198.1 - 0.048 13.4 0.1 0.21 11.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX79198.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX79198.1 - 0.58 9.9 8.7 0.83 9.4 8.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1493 PF07377.12 EAX79199.1 - 0.012 16.0 0.6 0.023 15.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX79200.1 - 1.8e-62 209.5 6.4 2e-62 209.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX79201.1 - 0.061 13.1 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DAO_C PF16901.5 EAX79201.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Ndc1_Nup PF09531.10 EAX79201.1 - 0.12 11.1 0.6 0.13 10.9 0.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup T5orf172 PF10544.9 EAX79202.1 - 3.3e-08 34.0 0.4 7e-08 32.9 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX79202.1 - 0.077 13.7 0.5 0.23 12.2 0.5 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4106 PF13388.6 EAX79203.1 - 7e-274 908.4 20.4 7e-274 908.4 20.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX79203.1 - 0.016 15.5 0.1 0.99 9.7 0.2 2.9 2 0 0 2 2 2 0 Kidney androgen-regulated DUF3839 PF12943.7 EAX79204.1 - 1.9e-157 522.0 14.2 2.1e-157 521.8 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79204.1 - 0.66 10.5 7.2 1.6 9.2 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX79205.1 - 0.048 13.6 8.1 0.075 13.0 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX79206.1 - 0.058 13.8 1.5 0.076 13.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79206.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX79208.1 - 3.1e-35 120.4 1.1 4.8e-35 119.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79208.1 - 0.013 16.2 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family RPAP3_C PF13877.6 EAX79208.1 - 0.024 15.2 1.3 0.073 13.6 0.3 2.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 DUF2344 PF10105.9 EAX79208.1 - 0.059 13.2 0.8 0.11 12.3 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) T5orf172 PF10544.9 EAX79209.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Pkinase PF00069.25 EAX79211.1 - 4.7e-55 186.8 0.0 5.8e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX79211.1 - 4.4e-29 101.6 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX79211.1 - 4.1e-08 32.9 0.0 1.5e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF3839 PF12943.7 EAX79212.1 - 6.5e-52 176.4 5.1 8.6e-52 176.0 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rab5-bind PF09311.11 EAX79212.1 - 0.0094 15.4 0.4 0.012 15.0 0.4 1.2 1 0 0 1 1 1 1 Rabaptin-like protein Fez1 PF06818.15 EAX79212.1 - 0.01 16.3 0.5 0.011 16.2 0.5 1.1 1 0 0 1 1 1 0 Fez1 T5orf172 PF10544.9 EAX79214.1 - 2.3e-06 28.1 0.2 5e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79214.1 - 0.013 15.4 0.1 0.048 13.5 0.0 2.0 2 1 0 2 2 2 0 KilA-N domain FAS_N PF17828.1 EAX79215.1 - 0.008 16.2 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX79215.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX79216.1 - 0.03 14.7 1.0 0.035 14.5 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX79216.1 - 2 7.4 3.5 2.2 7.3 3.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX79216.1 - 2.4 8.2 6.8 2.7 8.0 6.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX79217.1 - 0.13 12.3 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX79218.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX79219.1 - 4.9e-09 35.6 0.9 7.5e-09 35.0 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79219.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX79219.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Podoplanin PF05808.11 EAX79221.1 - 0.0017 18.5 0.1 0.0037 17.4 0.1 1.6 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 EAX79221.1 - 0.0028 17.9 0.7 0.0053 17.0 0.1 1.8 2 0 0 2 2 2 1 Glycophorin A Orf78 PF06024.12 EAX79221.1 - 0.0044 17.3 0.4 0.08 13.2 0.1 2.7 3 0 0 3 3 3 1 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 EAX79221.1 - 0.011 15.5 3.7 0.019 14.7 3.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECSCR PF15820.5 EAX79221.1 - 0.015 15.1 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF3823_C PF18003.1 EAX79221.1 - 0.021 15.5 0.3 11 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3823_C) DUF5385 PF17359.2 EAX79221.1 - 0.022 14.3 2.4 0.49 9.9 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF4448 PF14610.6 EAX79221.1 - 0.029 14.2 0.6 0.08 12.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Stevor PF17410.2 EAX79221.1 - 0.045 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 EAX79221.1 - 0.051 12.4 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EAX79221.1 - 0.064 14.1 0.3 0.17 12.8 0.1 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 EAX79221.1 - 0.092 13.0 0.2 0.24 11.6 0.2 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Syndecan PF01034.20 EAX79221.1 - 0.1 12.6 0.5 0.1 12.6 0.5 1.7 2 0 0 2 2 2 0 Syndecan domain DUF4307 PF14155.6 EAX79221.1 - 0.14 12.0 1.8 5.8 6.8 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4307) Otopetrin PF03189.13 EAX79221.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Otopetrin PTP_tm PF18861.1 EAX79221.1 - 0.18 11.8 2.7 1.2 9.1 1.6 2.4 2 1 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MtrF PF09472.10 EAX79221.1 - 0.28 10.6 2.7 0.52 9.7 2.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 EAX79221.1 - 1.3 8.5 10.5 2.3 7.7 10.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ABC2_membrane_3 PF12698.7 EAX79221.1 - 8.2 5.4 6.8 13 4.7 5.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Nucleopor_Nup85 PF07575.13 EAX79222.1 - 0.0036 15.9 0.0 0.006 15.2 0.0 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin KilA-N PF04383.13 EAX79223.1 - 4.5e-31 107.0 1.7 4.7e-31 106.9 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79223.1 - 0.0045 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX79223.1 - 0.78 10.2 6.3 4.9 7.7 1.7 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX79224.1 - 3.3e-07 30.0 3.0 5e-07 29.4 3.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79224.1 - 0.0045 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79224.1 - 0.055 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79224.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79224.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79224.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79224.1 - 0.44 10.7 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX79225.1 - 5.7e-07 30.0 0.2 1.1e-06 29.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Amidase02_C PF12123.8 EAX79226.1 - 0.0038 16.9 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase StbA PF06406.11 EAX79227.1 - 0.026 13.8 0.2 0.03 13.6 0.2 1.0 1 0 0 1 1 1 0 StbA protein AKAP95 PF04988.12 EAX79227.1 - 0.051 13.8 0.2 0.18 12.0 0.1 1.7 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Pox_A32 PF04665.12 EAX79228.1 - 6.2e-07 29.1 3.1 6.2e-07 29.1 3.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79228.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79228.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79228.1 - 0.00014 21.9 3.2 0.00035 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79228.1 - 0.00063 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79228.1 - 0.0012 18.7 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79228.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79228.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79228.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79228.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79228.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79228.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX79229.1 - 6.5e-37 125.8 1.6 8e-37 125.5 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79229.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX79229.1 - 0.22 10.1 0.2 0.29 9.7 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX79231.1 - 9.3e-154 509.9 12.0 1.1e-153 509.6 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79231.1 - 0.16 12.4 4.2 8 7.0 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX79232.1 - 6.1e-05 23.0 0.3 6.1e-05 23.0 0.3 3.9 5 0 0 5 5 5 1 Phage tail repeat like DUF445 PF04286.12 EAX79232.1 - 0.003 17.4 5.5 0.0042 17.0 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX79232.1 - 0.04 14.4 0.7 0.17 12.3 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX79232.1 - 0.052 13.3 0.1 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4116 PF13475.6 EAX79232.1 - 0.1 12.4 0.1 0.33 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX79232.1 - 2.6 7.6 14.1 0.23 11.0 6.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF5365 PF17326.2 EAX79233.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Tecti-min-caps PF09300.10 EAX79234.1 - 0.12 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Tectiviridae, minor capsid Pox_A32 PF04665.12 EAX79235.1 - 6.4e-06 25.8 0.5 7.4e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX79235.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4107 PF13389.6 EAX79236.1 - 1e-71 240.4 3.0 1.3e-71 240.0 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Herp-Cyclin PF09241.10 EAX79237.1 - 0.0028 18.3 0.1 0.0068 17.0 0.1 1.7 1 0 0 1 1 1 1 Herpesviridae viral cyclin HtrL_YibB PF09612.10 EAX79237.1 - 0.086 12.4 0.2 0.086 12.4 0.2 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (HtrL_YibB) KilA-N PF04383.13 EAX79239.1 - 1.5e-17 63.4 0.1 2.9e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF846 PF05832.12 EAX79240.1 - 0.032 14.3 0.1 0.064 13.3 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF3839 PF12943.7 EAX79243.1 - 7.2e-158 523.3 12.4 8.2e-158 523.1 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79243.1 - 0.19 11.6 1.8 0.53 10.1 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79243.1 - 0.23 12.0 6.4 1.2 9.7 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79244.1 - 7.9e-41 138.4 0.2 1.9e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79244.1 - 0.032 14.8 0.0 0.091 13.4 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX79245.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79247.1 - 5.5e-33 113.2 0.3 1.3e-32 112.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain PTR PF12789.7 EAX79249.1 - 3.2e-05 23.9 0.6 3.2e-05 23.9 0.6 3.7 5 1 0 5 5 5 1 Phage tail repeat like DUF445 PF04286.12 EAX79249.1 - 0.042 13.6 6.8 0.073 12.9 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX79249.1 - 0.69 9.5 19.5 90 2.6 19.5 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX79249.1 - 3.2 8.3 6.4 0.6 10.6 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) PapD_N PF00345.20 EAX79252.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79252.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX79252.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX79253.1 - 0.0093 16.4 0.2 0.01 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) LpoB PF13036.6 EAX79253.1 - 0.083 12.8 0.5 0.11 12.5 0.5 1.1 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB FAS_N PF17828.1 EAX79254.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX79255.1 - 8e-80 267.8 9.9 1e-79 267.4 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79255.1 - 0.018 15.5 0.4 0.02 15.3 0.4 1.2 1 0 0 1 1 1 0 Fez1 RasGAP_C PF03836.15 EAX79255.1 - 0.027 14.6 0.3 0.047 13.8 0.3 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Peptidase_M49 PF03571.15 EAX79256.1 - 1.4e-147 492.4 0.0 1.7e-147 492.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF5403 PF17395.2 EAX79256.1 - 0.0012 19.1 0.2 3.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5403) RPN6_N PF18055.1 EAX79256.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain MnmE_helical PF12631.7 EAX79256.1 - 0.13 12.5 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 MnmE helical domain DUF3839 PF12943.7 EAX79257.1 - 1.1e-126 421.2 8.4 1.3e-126 421.0 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX79257.1 - 0.029 14.6 0.1 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 LD_cluster2 PF18163.1 EAX79257.1 - 0.099 12.2 0.2 0.3 10.6 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 DUF3781 PF12636.7 EAX79258.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX79259.1 - 1.4e-117 391.4 6.7 1.6e-117 391.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79259.1 - 2.8 8.3 5.7 11 6.3 0.1 3.1 2 1 0 2 2 2 0 Rx N-terminal domain Amidase02_C PF12123.8 EAX79260.1 - 0.0065 16.1 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX79260.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF1493 PF07377.12 EAX79261.1 - 0.03 14.8 0.6 0.061 13.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX79262.1 - 3e-08 33.6 1.2 3e-08 33.6 1.2 4.0 2 1 1 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX79262.1 - 0.027 14.3 7.7 0.044 13.6 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MeaB PF03308.16 EAX79262.1 - 0.17 10.8 1.2 0.27 10.2 0.9 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4795 PF16043.5 EAX79262.1 - 0.19 11.3 23.1 0.011 15.3 5.6 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX79262.1 - 0.21 12.1 4.6 0.23 11.9 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX79263.1 - 6.4e-62 207.7 5.6 7.1e-62 207.6 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79264.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79264.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79264.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX79265.1 - 5.2e-06 26.3 1.6 1e-05 25.3 0.1 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79265.1 - 0.017 15.7 0.1 0.036 14.7 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Nitr_red_alph_N PF14710.6 EAX79266.1 - 0.33 11.4 2.6 1.9 9.0 0.5 2.4 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Retrotrans_gag PF03732.17 EAX79266.1 - 0.35 11.2 3.5 9.6 6.6 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein RIG-I_C PF18119.1 EAX79266.1 - 1.5 8.8 3.9 0.6 10.1 0.8 1.7 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Pox_A32 PF04665.12 EAX79267.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79267.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79267.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79267.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79267.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79267.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) SBDS PF01172.18 EAX79270.1 - 5.7e-24 84.0 1.5 6.1e-24 83.9 0.6 1.4 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EAX79270.1 - 3.4e-09 36.7 0.0 7.6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF3877 PF12993.7 EAX79272.1 - 0.083 12.8 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) ARA70 PF12489.8 EAX79273.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DNA_pol_B_2 PF03175.13 EAX79274.1 - 5.8e-23 81.5 3.9 7.5e-23 81.1 3.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79275.1 - 0.008 15.5 0.3 0.0096 15.3 0.3 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX79275.1 - 0.1 12.7 1.1 0.17 11.9 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX79275.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain DUF4107 PF13389.6 EAX79278.1 - 1.9e-20 73.6 0.6 2.2e-20 73.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX79279.1 - 2.1e-80 269.7 10.2 2.8e-80 269.3 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79279.1 - 0.027 14.9 0.3 0.034 14.6 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX79279.1 - 0.029 14.9 0.6 0.051 14.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX79279.1 - 0.14 11.7 0.2 0.83 9.1 0.0 2.1 2 1 1 3 3 3 0 SLOG cluster2 T5orf172 PF10544.9 EAX79280.1 - 7.3e-05 23.3 0.2 0.00021 21.8 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79280.1 - 0.012 15.1 1.1 0.13 11.7 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX79280.1 - 0.013 15.4 0.1 0.049 13.5 0.0 2.0 2 1 0 2 2 2 0 KilA-N domain DUF4107 PF13389.6 EAX79281.1 - 1.4e-61 207.4 12.2 4.7e-60 202.4 12.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79281.1 - 0.11 12.9 0.5 0.14 12.5 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX79282.1 - 3.3e-10 39.4 3.0 1.5e-09 37.2 3.1 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79282.1 - 0.11 12.5 0.0 0.79 9.8 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX79282.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 T5orf172 PF10544.9 EAX79284.1 - 1e-06 29.2 0.1 2.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79284.1 - 0.039 13.8 0.3 0.33 10.8 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX79285.1 - 1.3e-33 115.2 0.6 2.8e-33 114.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79285.1 - 0.0026 17.9 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Stanniocalcin PF03298.13 EAX79286.1 - 0.069 12.5 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Stanniocalcin family Pox_A32 PF04665.12 EAX79287.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79287.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79287.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79287.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79287.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79287.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) VirE PF05272.11 EAX79288.1 - 0.043 13.6 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.9 EAX79288.1 - 0.091 11.7 0.2 8.2 5.2 0.0 2.1 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 EAX79288.1 - 0.092 12.2 0.7 0.23 10.9 0.1 1.9 1 1 1 2 2 2 0 Poxvirus A32 protein DNA_pol_B_2 PF03175.13 EAX79289.1 - 1.2e-23 83.8 11.3 5.1e-23 81.7 11.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79289.1 - 0.16 12.0 0.0 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX79291.1 - 3.5e-80 269.0 10.0 4.4e-80 268.6 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX79291.1 - 0.039 14.5 0.3 0.066 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX79291.1 - 0.088 12.7 1.0 0.29 11.0 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4795 PF16043.5 EAX79292.1 - 0.081 12.5 4.6 0.22 11.1 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX79293.1 - 3.2e-29 100.8 12.1 3.2e-29 100.8 12.1 4.4 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX79293.1 - 0.033 13.9 0.2 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX79293.1 - 3.7 7.5 9.0 2.4 8.1 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF240) EF-hand_10 PF14788.6 EAX79294.1 - 0.0042 16.9 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 EF hand YABBY PF04690.13 EAX79294.1 - 0.019 15.5 2.0 0.024 15.2 0.8 1.7 2 0 0 2 2 2 0 YABBY protein T5orf172 PF10544.9 EAX79296.1 - 5.7e-07 30.0 0.3 1.1e-06 29.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX79296.1 - 0.13 12.9 0.4 0.34 11.6 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX79297.1 - 2.8e-33 114.1 1.6 3.5e-33 113.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX79297.1 - 0.057 13.4 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon ResIII PF04851.15 EAX79298.1 - 0.00023 21.2 4.4 0.00032 20.8 3.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79298.1 - 0.00048 20.0 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79298.1 - 0.00055 20.2 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79298.1 - 0.0027 17.6 2.4 0.0044 16.8 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79298.1 - 0.0096 16.3 0.0 0.014 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79298.1 - 0.023 14.4 0.3 0.12 12.1 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein TPK_catalytic PF04263.16 EAX79298.1 - 0.029 14.4 0.7 0.48 10.5 0.7 2.3 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX79298.1 - 0.054 12.9 0.1 0.082 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX79298.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79298.1 - 1.3 9.3 6.8 6 7.2 0.2 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX79298.1 - 2 9.1 11.3 0.16 12.6 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAX79299.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GPS2_interact PF15784.5 EAX79300.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79300.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX79302.1 - 1.9e-156 518.7 14.3 2.4e-156 518.3 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX79302.1 - 0.066 13.6 0.6 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX79302.1 - 0.2 11.5 1.3 0.59 10.0 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79302.1 - 1.5 9.4 6.2 7.3 7.1 0.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX79303.1 - 8.9e-152 503.4 13.6 1e-151 503.2 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79303.1 - 0.098 12.5 1.2 0.34 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79303.1 - 3.5 8.1 8.3 1.3 9.5 0.8 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX79304.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX79304.1 - 0.16 11.8 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX79305.1 - 2.4e-07 30.5 0.8 1.2e-06 28.2 0.1 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX79305.1 - 0.021 14.5 0.1 0.81 9.3 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 EAX79305.1 - 0.048 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TK PF00265.18 EAX79305.1 - 0.064 13.1 0.2 0.095 12.6 0.2 1.3 1 0 0 1 1 1 0 Thymidine kinase HD_3 PF13023.6 EAX79306.1 - 0.054 13.4 1.0 0.065 13.2 1.0 1.1 1 0 0 1 1 1 0 HD domain Presenilin PF01080.17 EAX79306.1 - 1.4 7.6 2.4 1.5 7.5 2.4 1.0 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 EAX79306.1 - 3.4 6.6 9.8 4.2 6.3 9.8 1.0 1 0 0 1 1 1 0 Paf1 DUF4108 PF13390.6 EAX79308.1 - 7.7e-64 213.9 6.1 8.6e-64 213.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79309.1 - 5.9e-05 23.5 2.5 0.00026 21.4 2.5 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX79309.1 - 0.014 14.5 0.8 0.02 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4106 PF13388.6 EAX79310.1 - 2.1e-209 696.0 17.0 3.7e-209 695.2 17.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Vasculin PF15337.6 EAX79311.1 - 0.13 13.2 0.5 0.23 12.3 0.1 1.7 1 1 1 2 2 2 0 Vascular protein family Vasculin-like 1 Spo12 PF05032.12 EAX79311.1 - 2.9 7.9 11.0 0.19 11.6 3.4 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX79312.1 - 5.7e-07 29.3 2.5 5.7e-07 29.3 2.5 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79312.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX79312.1 - 0.00012 22.1 3.0 0.00028 20.9 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX79312.1 - 0.00023 21.0 0.2 0.59 9.8 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX79312.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79312.1 - 0.0014 18.4 0.7 0.0028 17.5 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79312.1 - 0.0021 17.7 0.6 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79312.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79312.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX79312.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX79312.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Atg14 PF10186.9 EAX79313.1 - 5.7 5.9 14.1 1.6 7.8 9.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Amidase02_C PF12123.8 EAX79314.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX79315.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PPDK_N PF01326.19 EAX79318.1 - 1.3e-20 73.9 0.0 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF3781 PF12636.7 EAX79319.1 - 0.022 14.6 0.8 0.038 13.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX79320.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79320.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79320.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79320.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79320.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79320.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX79321.1 - 4.1e-36 123.2 0.7 6.5e-36 122.6 0.7 1.3 1 0 0 1 1 1 1 KilA-N domain HECA PF15353.6 EAX79321.1 - 0.022 15.0 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 Headcase protein family homologue DUF5446 PF17522.2 EAX79322.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX79323.1 - 1.2e-120 401.4 11.6 1.5e-120 401.1 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79323.1 - 0.051 14.0 0.7 5.2 7.6 0.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX79323.1 - 0.088 12.7 0.7 0.29 11.0 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX79324.1 - 0.088 12.5 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX79324.1 - 0.15 11.9 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) FAS_N PF17828.1 EAX79326.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX79327.1 - 0.013 15.8 0.3 0.016 15.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF2167 PF09935.9 EAX79327.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF4106 PF13388.6 EAX79328.1 - 1.9e-254 844.3 45.3 1.4e-252 838.2 45.3 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX79328.1 - 0.028 14.7 0.1 1 9.7 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX79328.1 - 0.077 12.8 1.9 0.08 12.8 0.2 1.9 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Pkinase PF00069.25 EAX79329.1 - 5e-25 88.3 0.0 9e-25 87.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX79329.1 - 4.7e-16 58.8 0.0 7.2e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX79329.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX79329.1 - 0.018 15.0 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2236 PF09995.9 EAX79329.1 - 0.18 12.0 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) GPS2_interact PF15784.5 EAX79331.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79331.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF2400 PF09674.10 EAX79335.1 - 0.024 14.6 0.6 0.037 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX79335.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX79336.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX79336.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ABC_tran PF00005.27 EAX79337.1 - 6.3e-11 43.0 0.0 1.1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX79337.1 - 0.0008 19.3 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX79337.1 - 0.13 11.7 0.6 0.17 11.3 0.1 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3819 PF12842.7 EAX79338.1 - 0.17 11.8 4.1 0.18 11.7 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Pox_A32 PF04665.12 EAX79339.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79339.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79339.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79339.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX79340.1 - 9.6e-33 112.4 0.3 2.3e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79340.1 - 0.0094 16.6 0.1 0.024 15.3 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family KilA-N PF04383.13 EAX79342.1 - 6.1e-42 142.0 0.1 6.1e-42 142.0 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain UCH PF00443.29 EAX79343.1 - 3e-19 69.5 0.2 3.6e-19 69.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX79343.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4116 PF13475.6 EAX79344.1 - 0.0091 15.7 0.4 0.05 13.3 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) TMP PF05017.14 EAX79346.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX79349.1 - 6.5e-79 264.8 10.6 8.6e-79 264.4 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Mem_trans PF03547.18 EAX79352.1 - 6.4e-14 51.1 3.1 7.5e-14 50.9 3.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Orthoreo_P10 PF07204.11 EAX79352.1 - 0.047 13.6 0.7 0.047 13.6 0.7 1.7 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 SBF PF01758.16 EAX79352.1 - 0.18 11.4 12.7 0.047 13.4 8.6 1.8 1 1 1 2 2 2 0 Sodium Bile acid symporter family DUF4107 PF13389.6 EAX79353.1 - 3.5e-72 241.8 4.8 4.3e-72 241.6 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX79353.1 - 0.18 10.2 1.1 0.26 9.7 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX79354.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Fip1 PF05182.13 EAX79355.1 - 0.069 12.7 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Fip1 motif DNA_pol_B_2 PF03175.13 EAX79356.1 - 4.9e-25 88.3 10.7 2.2e-24 86.2 10.6 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79356.1 - 0.11 12.5 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX79356.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Meiosis_expr PF15163.6 EAX79357.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX79357.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX79357.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family KilA-N PF04383.13 EAX79358.1 - 4.9e-15 55.3 1.1 9.2e-15 54.5 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79358.1 - 0.019 15.6 0.1 0.04 14.5 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX79359.1 - 2.4e-07 30.4 2.8 3.5e-07 29.9 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79359.1 - 0.0041 16.8 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79359.1 - 0.043 13.3 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79359.1 - 0.058 13.1 0.1 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79359.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79359.1 - 0.17 11.8 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79359.1 - 0.35 11.1 8.5 5.4 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX79363.1 - 0.0038 16.9 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX79363.1 - 0.22 11.4 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX79364.1 - 6.1e-63 211.0 5.9 6.7e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX79365.1 - 0.059 13.3 3.0 0.11 12.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3417 PF11897.8 EAX79365.1 - 0.1 13.1 0.4 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) PTR PF12789.7 EAX79366.1 - 3.2e-09 36.7 12.1 1.8e-08 34.3 5.5 4.4 5 1 0 5 5 5 2 Phage tail repeat like DUF4805 PF16063.5 EAX79366.1 - 0.25 10.6 2.2 10 5.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Pox_A32 PF04665.12 EAX79368.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79368.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79368.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79368.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79368.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79368.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79368.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79368.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79368.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79368.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79368.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79368.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX79369.1 - 1.8e-44 150.2 0.3 4.6e-44 148.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX79370.1 - 4.2e-06 27.3 0.2 1.2e-05 25.8 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79370.1 - 0.022 14.6 0.3 0.11 12.3 0.1 2.3 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX79370.1 - 0.038 13.5 0.1 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF4108 PF13390.6 EAX79372.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX79374.1 - 2e-05 24.6 0.3 3e-05 24.1 0.3 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79374.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79374.1 - 0.00043 20.6 0.0 0.00062 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79374.1 - 0.0019 18.0 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79374.1 - 0.0072 16.7 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79374.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX79374.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein SWI2_SNF2 PF18766.1 EAX79374.1 - 0.084 12.5 0.2 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX79374.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX79374.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1493 PF07377.12 EAX79375.1 - 0.013 15.9 0.6 0.026 15.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX79376.1 - 2.7e-31 107.4 9.8 2.7e-31 107.4 9.8 3.8 3 1 0 3 3 3 1 Phage tail repeat like DUF3839 PF12943.7 EAX79378.1 - 4e-156 517.6 16.5 5e-156 517.3 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX79378.1 - 0.096 13.1 0.4 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79378.1 - 2.7 8.5 8.2 2.5 8.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79379.1 - 2.1e-41 140.2 0.4 6e-41 138.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX79379.1 - 0.011 14.9 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase DNA_pol_B_2 PF03175.13 EAX79380.1 - 3.5e-29 102.0 7.0 6e-29 101.2 7.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79380.1 - 0.035 13.4 0.2 0.058 12.7 0.2 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5106 PF17127.4 EAX79380.1 - 0.091 13.0 0.1 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) T5orf172 PF10544.9 EAX79381.1 - 0.00031 21.2 0.1 0.00078 20.0 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79381.1 - 0.021 14.7 2.1 0.057 13.3 1.0 2.3 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX79382.1 - 1.4e-79 267.0 10.5 1.8e-79 266.6 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF641 PF04859.12 EAX79383.1 - 0.015 15.7 1.7 0.021 15.2 1.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 EAX79383.1 - 0.089 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pertus-S5-tox PF09276.10 EAX79383.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 Pertussis toxin S5 subunit DHR10 PF18595.1 EAX79383.1 - 0.21 11.7 5.0 0.34 11.0 3.8 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 EAX79383.1 - 0.21 11.7 8.6 0.25 11.5 0.0 2.6 2 1 1 3 3 3 0 bZIP transcription factor Sec8_exocyst PF04048.14 EAX79383.1 - 0.23 11.4 2.5 2.5 8.0 1.5 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TMP PF05017.14 EAX79386.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79387.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FAS_N PF17828.1 EAX79388.1 - 0.004 17.2 0.1 0.0064 16.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DinB PF05163.12 EAX79388.1 - 0.084 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 DinB family DUF4576 PF15144.6 EAX79388.1 - 0.15 12.0 3.2 0.099 12.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) Pox_A32 PF04665.12 EAX79389.1 - 2.2e-07 30.6 2.4 3.2e-07 30.1 2.4 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79389.1 - 0.0047 16.6 0.1 0.0062 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79389.1 - 0.067 12.9 0.1 0.21 11.3 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79389.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79389.1 - 0.2 11.6 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) HTH_AraC PF00165.23 EAX79390.1 - 0.094 12.8 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family T5orf172 PF10544.9 EAX79391.1 - 2.9e-07 31.0 0.2 7.5e-07 29.6 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79391.1 - 0.0038 16.8 0.6 0.049 13.2 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX79391.1 - 0.014 15.2 0.7 0.042 13.7 0.3 2.1 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX79392.1 - 1e-28 100.4 6.2 1.5e-28 99.9 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX79392.1 - 0.013 14.7 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3839 PF12943.7 EAX79393.1 - 9.1e-107 356.0 8.2 1e-106 355.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX79395.1 - 3.9e-29 101.9 4.8 3.6e-27 95.5 4.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2960 PF11173.8 EAX79396.1 - 0.015 15.7 0.3 0.044 14.2 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) Amidase02_C PF12123.8 EAX79398.1 - 0.0031 17.2 0.1 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX79399.1 - 2.3e-156 518.4 13.8 2.7e-156 518.2 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79399.1 - 0.21 11.4 1.3 0.67 9.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79399.1 - 0.78 10.2 8.2 2.6 8.6 1.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79400.1 - 2e-34 117.8 0.5 4.4e-34 116.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX79401.1 - 6e-07 29.9 0.5 1.6e-06 28.6 0.3 1.8 2 1 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EAX79401.1 - 0.16 12.6 0.4 0.45 11.2 0.4 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX79402.1 - 8.1e-16 57.9 1.3 1.5e-15 57.0 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79402.1 - 0.0029 18.2 0.0 0.0066 17.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX79403.1 - 1.7e-07 30.9 3.1 2.4e-07 30.5 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79403.1 - 0.0029 17.3 0.2 0.0036 17.0 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79403.1 - 0.052 13.1 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79403.1 - 0.056 13.2 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79403.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX79403.1 - 0.38 11.0 8.5 5.5 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF2939 PF11159.8 EAX79405.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX79405.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX79406.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX79406.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal PapD_N PF00345.20 EAX79408.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79408.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX79409.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX79409.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX79410.1 - 0.009 16.0 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta GGDEF PF00990.21 EAX79412.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain ARGLU PF15346.6 EAX79412.1 - 0.039 13.8 14.4 0.058 13.3 14.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GAGA_bind PF06217.12 EAX79412.1 - 0.054 13.8 4.3 0.064 13.5 4.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Btz PF09405.10 EAX79412.1 - 0.3 11.4 8.5 0.6 10.4 8.5 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PcfK PF14058.6 EAX79412.1 - 0.3 11.4 14.1 0.44 10.8 14.1 1.3 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX79412.1 - 5.2 7.0 7.8 12 5.8 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3464 PF11947.8 EAX79412.1 - 7.8 6.2 6.4 7.8 6.2 5.7 1.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX79413.1 - 1.7e-57 193.3 8.6 1.9e-57 193.2 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79414.1 - 5.5e-05 23.6 3.7 0.00038 20.9 3.7 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79414.1 - 0.064 13.9 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79414.1 - 0.076 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX79415.1 - 5.3e-27 93.9 0.9 1.1e-26 92.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79415.1 - 0.028 15.0 0.0 0.071 13.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DDE_1 PF03184.19 EAX79416.1 - 6.3e-17 61.8 0.0 8.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PTR PF12789.7 EAX79418.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.2 4 1 1 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX79418.1 - 0.055 13.2 0.1 0.2 11.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX79418.1 - 0.06 13.1 7.1 0.089 12.6 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MeaB PF03308.16 EAX79418.1 - 0.072 12.1 0.7 0.13 11.2 0.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX79418.1 - 0.083 13.3 4.2 0.18 12.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) YmaF PF12788.7 EAX79418.1 - 0.35 11.4 5.8 1 9.9 0.3 2.9 2 1 0 3 3 3 0 YmaF family DUF4795 PF16043.5 EAX79418.1 - 2.7 7.6 20.1 4.7e+03 -3.0 20.1 3.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4106 PF13388.6 EAX79420.1 - 9.9e-260 861.8 22.6 9.9e-260 861.8 22.6 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX79420.1 - 0.022 15.0 0.1 0.99 9.7 0.2 2.8 2 0 0 2 2 2 0 Kidney androgen-regulated WBS_methylT PF12589.8 EAX79420.1 - 0.89 10.3 6.2 34 5.3 0.1 3.3 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome WYL_3 PF18488.1 EAX79420.1 - 1.9 8.9 8.0 7.4 7.0 0.9 3.3 3 0 0 3 3 3 0 WYL domain DNA_methylase PF00145.17 EAX79421.1 - 0.21 10.9 15.1 0.26 10.6 15.1 1.0 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Red1 PF07964.11 EAX79421.1 - 2.2 6.4 32.5 2.1 6.5 32.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Asp-B-Hydro_N PF05279.11 EAX79421.1 - 2.5 8.1 27.7 3.2 7.8 27.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CCSAP PF15748.5 EAX79421.1 - 4.1 7.5 26.1 5.6 7.1 26.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Pox_D5 PF03288.16 EAX79422.1 - 1.9e-05 25.1 3.3 0.00014 22.3 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79422.1 - 0.074 13.7 0.2 0.13 12.9 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79422.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX79423.1 - 3.7e-58 195.5 9.0 4.1e-58 195.4 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79425.1 - 1.1e-157 522.7 14.8 1.3e-157 522.5 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79425.1 - 0.098 12.9 0.2 2.1 8.7 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX79425.1 - 0.23 11.3 1.4 0.8 9.5 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79425.1 - 0.64 10.5 7.0 2.1 8.8 0.8 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX79426.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX79427.1 - 1 9.3 4.1 2 8.4 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX79428.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX79428.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79428.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79428.1 - 0.00089 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79428.1 - 0.0026 17.5 0.2 0.27 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX79428.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79428.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX79428.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX79428.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79428.1 - 0.25 11.6 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX79430.1 - 0.044 14.3 5.1 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79431.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX79433.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79433.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GGDEF PF00990.21 EAX79435.1 - 0.067 12.9 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX79435.1 - 0.2 11.9 10.1 0.31 11.3 10.1 1.4 1 1 0 1 1 1 0 PcfK-like protein Pox_D5 PF03288.16 EAX79436.1 - 5.6e-05 23.6 2.9 0.00036 21.0 2.9 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX79437.1 - 3.2e-117 390.2 6.6 3.6e-117 390.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX79437.1 - 0.043 13.3 0.5 0.062 12.8 0.4 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX79437.1 - 0.12 13.0 0.9 0.59 10.8 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5398) EF-hand_10 PF14788.6 EAX79439.1 - 0.0025 17.7 0.1 0.0075 16.1 0.1 1.8 1 0 0 1 1 1 1 EF hand YABBY PF04690.13 EAX79439.1 - 0.0083 16.7 0.7 0.017 15.7 0.7 1.4 1 0 0 1 1 1 1 YABBY protein GPS2_interact PF15784.5 EAX79441.1 - 0.03 14.8 0.6 0.036 14.5 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX79442.1 - 0.021 14.8 8.3 0.027 14.4 8.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX79442.1 - 1.4 9.3 5.6 1.9 8.9 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX79443.1 - 1.3e-124 414.4 6.9 1.5e-124 414.3 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79443.1 - 0.049 14.1 3.3 2.1 8.9 2.1 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Z1 PF10593.9 EAX79443.1 - 0.06 12.9 0.9 0.091 12.2 0.6 1.4 1 1 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX79444.1 - 1.2e-41 141.0 0.1 2e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain PapD_N PF00345.20 EAX79446.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79446.1 - 0.049 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX79446.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PTR PF12789.7 EAX79448.1 - 1e-05 25.5 1.1 1e-05 25.5 1.1 4.7 6 0 0 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX79448.1 - 0.025 14.3 0.1 0.1 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX79448.1 - 0.042 12.8 1.0 0.075 12.0 1.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX79448.1 - 0.61 9.8 10.6 1.2 8.8 9.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX79448.1 - 0.76 10.3 3.5 0.7 10.4 0.1 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF2120 PF09893.9 EAX79448.1 - 0.96 9.6 4.6 1.5 8.9 0.7 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) YmaF PF12788.7 EAX79448.1 - 1.9 9.1 4.7 5.2 7.7 1.0 3.2 3 1 0 3 3 3 0 YmaF family DUF4795 PF16043.5 EAX79448.1 - 3.5 7.2 20.5 0.024 14.2 6.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) T5orf172 PF10544.9 EAX79450.1 - 1.3e-06 28.9 0.3 2.6e-06 27.9 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX79450.1 - 0.063 14.0 0.3 0.15 12.8 0.3 1.6 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX79451.1 - 3.6e-43 145.9 0.4 9e-43 144.7 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79451.1 - 0.0066 17.1 0.1 0.028 15.0 0.0 2.1 2 0 0 2 2 2 1 Parathyroid hormone family RRP36 PF06102.12 EAX79451.1 - 0.43 10.5 9.2 0.094 12.7 3.3 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Rad51 PF08423.11 EAX79452.1 - 0.072 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Rad51 PapD_N PF00345.20 EAX79454.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79454.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX79455.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX79455.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX79455.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX79457.1 - 9.2e-08 31.8 0.7 1.1e-07 31.6 0.7 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79457.1 - 0.0034 17.1 0.1 0.0042 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79457.1 - 0.048 13.4 0.1 0.11 12.2 0.0 1.5 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79457.1 - 0.09 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX79458.1 - 1.6e-129 430.5 7.6 1.8e-129 430.4 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79458.1 - 0.087 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX79458.1 - 0.18 12.3 1.7 1.3 9.6 0.9 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX79458.1 - 0.57 10.5 2.7 2.2 8.6 0.0 2.7 2 1 0 2 2 2 0 Rx N-terminal domain T5orf172 PF10544.9 EAX79459.1 - 0.00095 19.7 0.2 0.0018 18.8 0.2 1.5 1 0 0 1 1 1 1 T5orf172 domain MG2 PF01835.19 EAX79461.1 - 1.5e-05 25.3 0.2 0.022 15.2 0.0 3.6 4 0 0 4 4 4 1 MG2 domain DUF4625 PF15418.6 EAX79461.1 - 4.6e-05 23.7 1.3 0.073 13.3 0.1 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4625) ChitinaseA_N PF08329.10 EAX79461.1 - 0.0055 16.3 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Chitinase A, N-terminal domain Y_Y_Y PF07495.13 EAX79461.1 - 0.034 14.1 1.4 9.7 6.2 0.3 3.4 2 1 1 3 3 3 0 Y_Y_Y domain NPCBM_assoc PF10633.9 EAX79461.1 - 0.036 14.3 3.6 0.15 12.3 0.1 3.3 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase bMG6 PF17962.1 EAX79461.1 - 0.13 12.5 0.4 2.1 8.5 0.1 2.8 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 Lipocalin PF00061.23 EAX79461.1 - 0.33 11.1 3.9 0.17 12.1 0.6 2.2 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family RIFIN PF02009.16 EAX79461.1 - 0.55 10.1 7.7 0.81 9.5 7.7 1.2 1 0 0 1 1 1 0 Rifin DUF4107 PF13389.6 EAX79462.1 - 2.6e-57 193.5 11.3 1.6e-55 187.7 11.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79462.1 - 0.086 13.2 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX79463.1 - 1.1e-57 193.9 5.9 1.2e-57 193.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79463.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide AAA_22 PF13401.6 EAX79465.1 - 2.5e-05 24.6 0.2 0.00017 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79465.1 - 4.1e-05 23.4 0.3 0.29 10.8 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX79465.1 - 0.00012 21.7 2.7 0.00012 21.7 2.7 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX79465.1 - 0.00022 21.3 3.4 0.00045 20.3 3.4 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79465.1 - 0.00042 20.1 0.0 0.00076 19.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79465.1 - 0.0013 18.6 0.8 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79465.1 - 0.0015 18.2 0.4 0.0086 15.7 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79465.1 - 0.011 16.1 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79465.1 - 0.04 14.3 0.1 0.38 11.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX79465.1 - 0.052 13.1 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX79465.1 - 0.061 12.8 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX79465.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79465.1 - 0.19 12.0 5.3 2.6 8.3 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3783 PF12646.7 EAX79465.1 - 0.22 11.5 1.7 1.6 8.7 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) TMP PF05017.14 EAX79466.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAX79467.1 - 0.099 12.8 0.2 24 5.2 0.1 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain PTR PF12789.7 EAX79468.1 - 6.1e-49 163.9 28.3 6.7e-33 112.6 15.9 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX79468.1 - 0.019 14.7 1.1 0.037 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX79469.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3781 PF12636.7 EAX79470.1 - 0.025 14.4 1.1 0.043 13.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TPR_MLP1_2 PF07926.12 EAX79471.1 - 0.016 15.3 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX79471.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79471.1 - 0.96 9.4 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX79472.1 - 5.1e-154 510.7 13.7 6.4e-154 510.4 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79472.1 - 0.072 13.4 0.5 1.4 9.2 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX79472.1 - 0.11 12.3 0.8 0.5 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX79472.1 - 0.12 12.8 0.4 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79472.1 - 1.3 9.5 7.6 2.1 8.9 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX79473.1 - 2.5e-155 515.0 14.0 3.2e-155 514.7 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79473.1 - 0.13 12.1 1.1 0.46 10.3 0.3 2.0 1 1 0 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX79473.1 - 0.73 10.4 4.7 1.7 9.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX79473.1 - 0.89 9.9 4.4 0.62 10.4 0.9 2.5 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX79473.1 - 8.6 6.9 8.4 5.7 7.5 0.6 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX79474.1 - 1.3e-37 129.8 16.0 7.1e-37 127.4 16.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral TFIIA PF03153.13 EAX79475.1 - 0.078 13.0 13.4 0.089 12.8 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EAX79475.1 - 4.1 6.0 11.4 4.8 5.7 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PTR PF12789.7 EAX79476.1 - 1.1e-46 156.7 27.6 1.4e-31 108.3 14.3 4.3 3 2 1 4 4 4 2 Phage tail repeat like DUF5448 PF17526.2 EAX79476.1 - 0.03 14.5 1.1 0.15 12.3 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5448) PBP5_C PF07943.13 EAX79476.1 - 0.067 13.4 0.8 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DNA_pol_B_2 PF03175.13 EAX79477.1 - 2.5e-10 39.8 0.1 4.7e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX79477.1 - 0.052 12.8 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF1493 PF07377.12 EAX79478.1 - 0.023 15.1 0.7 0.042 14.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79479.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79480.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX79481.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX79483.1 - 6e-05 23.0 1.2 6e-05 23.0 1.2 2.8 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX79483.1 - 0.29 11.7 5.5 2.5 8.7 1.6 3.0 2 1 0 2 2 2 0 YmaF family DUF3839 PF12943.7 EAX79484.1 - 2.6e-149 495.3 11.3 3.5e-149 494.9 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79484.1 - 0.021 15.3 0.7 0.063 13.7 0.1 1.9 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX79484.1 - 0.11 12.9 0.3 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79484.1 - 0.29 11.6 5.3 3 8.4 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_22 PF13401.6 EAX79485.1 - 5e-05 23.6 0.0 0.00029 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX79485.1 - 7.1e-05 22.9 3.0 0.00014 21.9 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79485.1 - 0.00041 20.2 0.0 0.00055 19.8 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79485.1 - 0.00071 19.4 0.8 0.002 17.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79485.1 - 0.0029 17.3 0.4 0.24 11.1 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX79485.1 - 0.0075 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79485.1 - 0.048 13.1 0.1 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX79485.1 - 0.086 12.6 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX79485.1 - 0.12 12.8 0.1 0.37 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX79485.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79485.1 - 0.17 12.2 4.0 5.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX79486.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79487.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX79488.1 - 9.9e-16 57.6 1.2 2.1e-15 56.6 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79488.1 - 0.0036 17.4 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Ribosomal_S18 PF01084.20 EAX79489.1 - 6.6e-06 26.3 0.1 0.13 12.5 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein S18 Gag_p10 PF02337.17 EAX79489.1 - 0.0036 17.2 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral GAG p10 protein Myb_DNA-bind_6 PF13921.6 EAX79489.1 - 0.0071 16.6 0.5 4.1 7.7 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Pox_A32 PF04665.12 EAX79490.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79490.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79490.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79490.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF5623 PF18536.1 EAX79492.1 - 0.081 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX79492.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX79494.1 - 1.2e-134 447.3 13.9 3.2e-134 445.9 13.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79494.1 - 0.053 14.0 2.2 0.093 13.2 0.4 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX79494.1 - 0.08 13.4 0.7 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79494.1 - 0.14 12.6 6.2 2.1 8.9 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX79495.1 - 3.7e-37 128.3 14.7 2e-36 125.9 14.7 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral ResIII PF04851.15 EAX79496.1 - 6.3e-05 23.1 2.8 0.00011 22.2 2.8 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79496.1 - 0.00035 20.4 0.0 0.00054 19.8 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79496.1 - 0.00038 20.8 0.0 0.00062 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79496.1 - 0.00066 19.5 0.8 0.0019 18.1 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79496.1 - 0.007 16.7 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79496.1 - 0.031 14.0 0.2 0.2 11.4 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX79496.1 - 0.042 13.3 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Terminase_6 PF03237.15 EAX79496.1 - 0.064 12.9 0.1 0.42 10.2 0.0 1.9 1 1 0 2 2 2 0 Terminase-like family AAA_25 PF13481.6 EAX79496.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79496.1 - 0.18 12.1 4.3 4.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX79496.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX79496.1 - 0.85 10.1 4.3 0.35 11.3 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX79499.1 - 2.5e-78 262.9 10.5 3.3e-78 262.5 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79499.1 - 0.26 11.1 2.0 0.82 9.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4108 PF13390.6 EAX79500.1 - 1.5e-60 203.2 9.0 1.7e-60 203.1 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) SH3BGR PF04908.15 EAX79501.1 - 0.78 9.9 4.1 0.67 10.2 2.9 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF2897 PF11446.8 EAX79501.1 - 1.9 8.4 3.7 4 7.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX79502.1 - 1e-06 28.4 4.1 1.1e-06 28.2 3.2 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein ResIII PF04851.15 EAX79502.1 - 9e-05 22.5 3.4 0.00018 21.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX79502.1 - 0.00018 21.3 0.3 0.41 10.4 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX79502.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79502.1 - 0.00091 19.5 0.2 0.0068 16.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79502.1 - 0.00095 19.0 0.8 0.0018 18.2 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79502.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79502.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX79502.1 - 0.12 12.0 0.0 0.41 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79502.1 - 0.18 12.1 2.9 9.8 6.5 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4795 PF16043.5 EAX79502.1 - 2.1 7.9 8.1 0.77 9.3 2.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF3464 PF11947.8 EAX79503.1 - 8.8 6.1 7.2 8.8 6.1 7.2 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX79504.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2960 PF11173.8 EAX79507.1 - 0.026 15.0 0.3 0.053 14.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX79507.1 - 0.055 13.5 1.8 0.17 11.9 0.5 2.2 2 1 1 3 3 3 0 YpjP-like protein GPS2_interact PF15784.5 EAX79508.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain IstB_IS21_ATP PF08483.11 EAX79509.1 - 1.3e-10 41.0 6.9 6.5e+02 0.3 0.0 19.0 25 0 0 25 25 25 0 IstB-like ATP binding N-terminal Lectin_like PF18560.1 EAX79509.1 - 9.5e-10 38.8 61.3 1.9 8.6 0.7 12.3 1 1 12 14 14 14 14 Lectin like domain BORG_CEP PF14957.6 EAX79509.1 - 5.4e-09 37.3 57.1 3.2 8.9 3.1 11.9 1 1 6 7 7 7 5 Cdc42 effector LDB19 PF13002.7 EAX79509.1 - 1e-05 25.3 18.1 6.6 6.4 0.0 9.0 1 1 8 11 11 11 2 Arrestin_N terminal like KAAG1 PF15354.6 EAX79509.1 - 0.00015 22.2 53.2 4.1 8.0 0.4 11.0 1 1 16 17 17 17 5 Kidney-associated antigen 1 HTH_24 PF13412.6 EAX79509.1 - 0.019 14.5 8.4 5.8 6.6 0.1 4.9 5 0 0 5 5 5 0 Winged helix-turn-helix DNA-binding PK_C PF02887.16 EAX79509.1 - 0.027 14.7 8.5 24 5.2 0.0 5.8 2 1 2 4 4 4 0 Pyruvate kinase, alpha/beta domain DUF3839 PF12943.7 EAX79510.1 - 2.3e-155 515.1 12.9 2.8e-155 514.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79510.1 - 1 9.9 5.7 2.1 8.9 0.9 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX79513.1 - 0.031 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79513.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pox_D5 PF03288.16 EAX79514.1 - 9.3e-05 22.8 1.9 0.00043 20.7 1.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX79515.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Spo12 PF05032.12 EAX79517.1 - 0.078 12.9 2.2 0.078 12.9 2.2 2.4 3 0 0 3 3 3 0 Spo12 family DUF5623 PF18536.1 EAX79517.1 - 0.08 13.2 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) DUF5365 PF17326.2 EAX79518.1 - 0.03 14.7 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX79518.1 - 0.071 13.4 0.3 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain FAS_N PF17828.1 EAX79519.1 - 0.0089 16.0 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Peptidase_C14 PF00656.22 EAX79519.1 - 0.025 14.5 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 Caspase domain GPS2_interact PF15784.5 EAX79521.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79521.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX79522.1 - 1.8e-120 400.8 11.9 2.3e-120 400.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79522.1 - 0.041 14.3 2.8 1.6 9.2 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX79522.1 - 0.047 13.6 1.0 0.19 11.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX79523.1 - 0.00078 19.4 0.0 0.00078 19.4 0.0 3.0 4 0 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX79523.1 - 1.5 9.4 5.5 6.8 7.3 2.1 2.9 2 1 0 2 2 2 0 YmaF family DDR PF08841.10 EAX79526.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Collagen_bind_2 PF12904.7 EAX79527.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase PWI PF01480.17 EAX79528.1 - 0.016 15.5 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 PWI domain OmdA PF13376.6 EAX79528.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF2939 PF11159.8 EAX79529.1 - 0.073 13.5 0.3 0.087 13.2 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX79530.1 - 0.028 14.4 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX79530.1 - 0.092 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal HNH_3 PF13392.6 EAX79531.1 - 1.2e-07 31.3 0.3 2.2e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Csm2_III-A PF03750.13 EAX79532.1 - 0.022 15.6 0.6 0.027 15.3 0.6 1.1 1 0 0 1 1 1 0 Csm2 Type III-A TPR_MLP1_2 PF07926.12 EAX79532.1 - 0.023 14.8 0.2 0.029 14.4 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX79532.1 - 0.041 13.7 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79532.1 - 0.25 11.3 7.2 0.12 12.3 2.5 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX79533.1 - 2.1e-06 28.2 0.4 6.6e-06 26.6 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX79533.1 - 0.0063 16.1 0.6 0.083 12.4 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain DUF5446 PF17522.2 EAX79535.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX79536.1 - 1.7e-79 266.7 10.0 2.2e-79 266.3 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79536.1 - 0.089 12.6 0.9 0.35 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF5446 PF17522.2 EAX79537.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4108 PF13390.6 EAX79538.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) SH3BGR PF04908.15 EAX79539.1 - 0.032 14.4 1.0 0.054 13.7 1.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein ResIII PF04851.15 EAX79540.1 - 2.3e-05 24.4 1.2 4.4e-05 23.6 1.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79540.1 - 0.00031 20.6 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79540.1 - 0.00039 20.7 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79540.1 - 0.0011 18.8 0.1 0.0019 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79540.1 - 0.0064 16.8 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79540.1 - 0.036 13.5 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX79540.1 - 0.061 13.0 0.4 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX79540.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX79540.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX79540.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX79540.1 - 0.69 10.3 3.7 0.35 11.3 0.7 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1493 PF07377.12 EAX79541.1 - 0.029 14.8 0.6 0.078 13.4 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79542.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79543.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP Mito_fiss_reg PF05308.11 EAX79544.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX79544.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4107 PF13389.6 EAX79545.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX79546.1 - 0.009 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX79547.1 - 3.9e-157 520.9 13.4 4.6e-157 520.7 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79547.1 - 0.45 10.8 4.0 1.2 9.5 0.0 3.1 2 2 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX79547.1 - 0.72 10.3 7.5 2.2 8.8 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX79548.1 - 4.9e-211 701.3 20.8 4.9e-211 701.3 20.8 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) Peptidase_M49 PF03571.15 EAX79549.1 - 5.4e-42 143.9 0.0 6.1e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Chromadorea_ALT PF05535.12 EAX79549.1 - 0.2 11.9 0.4 0.2 11.9 0.4 1.7 2 0 0 2 2 2 0 Chromadorea ALT protein DUF3839 PF12943.7 EAX79550.1 - 1.8e-153 508.9 13.8 2.1e-153 508.7 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79550.1 - 0.098 12.5 1.1 0.38 10.6 0.5 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase PA28_beta PF02252.18 EAX79550.1 - 0.14 11.9 4.2 0.38 10.4 1.0 2.8 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX79550.1 - 0.36 11.1 2.2 0.89 9.9 1.0 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX79550.1 - 1.2 9.6 7.3 2.1 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX79550.1 - 1.5 9.2 5.5 6.1 7.2 0.0 3.2 2 2 2 4 4 4 0 Rx N-terminal domain KilA-N PF04383.13 EAX79551.1 - 2.9e-10 40.0 0.0 7.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX79552.1 - 9.1e-156 516.4 12.4 1.1e-155 516.1 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79552.1 - 0.1 12.9 0.3 2.3 8.5 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX79552.1 - 0.94 10.0 4.9 8.6 6.9 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GGDEF PF00990.21 EAX79553.1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX79553.1 - 1.3 9.0 5.3 2.6 8.0 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79554.1 - 3.1e-54 182.8 7.7 3.4e-54 182.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79554.1 - 0.13 12.6 0.1 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide TPR_MLP1_2 PF07926.12 EAX79555.1 - 0.037 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX79555.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX79555.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Spore_coat_CotO PF14153.6 EAX79556.1 - 0.007 16.3 5.6 0.0097 15.9 5.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO FAS_N PF17828.1 EAX79556.1 - 0.0074 16.3 0.2 0.01 15.8 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX79557.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX79557.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX79558.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79558.1 - 0.09 12.8 0.5 0.14 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) KilA-N PF04383.13 EAX79559.1 - 1.5e-43 147.2 0.4 3.3e-43 146.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79559.1 - 0.013 16.2 0.3 0.045 14.4 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX79561.1 - 8.9e-149 493.5 16.2 1.1e-148 493.2 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX79561.1 - 0.042 13.4 0.1 0.19 11.3 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 Fez1 PF06818.15 EAX79561.1 - 0.073 13.5 2.1 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX79561.1 - 0.089 13.1 1.5 0.97 9.8 0.1 3.2 3 1 1 4 4 4 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX79561.1 - 0.11 12.9 0.2 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX79561.1 - 0.17 11.7 1.4 0.52 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79561.1 - 0.27 11.7 7.5 1.9 9.0 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX79562.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_D5 PF03288.16 EAX79564.1 - 0.00015 22.2 2.2 0.00076 19.9 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79564.1 - 0.043 14.4 0.1 0.089 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79564.1 - 0.082 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX79565.1 - 7.1e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX79565.1 - 0.088 13.3 0.3 0.61 10.6 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF4107 PF13389.6 EAX79567.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX79568.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF2897 PF11446.8 EAX79569.1 - 1.8 8.5 3.7 3.8 7.5 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79570.1 - 1.9e-63 212.7 6.2 2.1e-63 212.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX79571.1 - 0.028 14.9 0.8 0.061 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79572.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79573.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX79574.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79575.1 - 0.064 13.1 0.8 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX79576.1 - 3.8e-54 183.7 3.7 4.3e-54 183.5 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MvaI_BcnI PF15515.6 EAX79576.1 - 0.026 14.3 0.6 3.2 7.5 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family Z1 PF10593.9 EAX79576.1 - 0.067 12.7 0.1 0.074 12.5 0.1 1.0 1 0 0 1 1 1 0 Z1 domain DNA_pol_B_2 PF03175.13 EAX79578.1 - 6e-09 35.3 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX79578.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX79578.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX79579.1 - 0.036 14.0 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79579.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family LRV PF01816.17 EAX79580.1 - 0.61 10.6 4.1 32 5.2 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat variant HEAT_EZ PF13513.6 EAX79580.1 - 5.2 7.7 15.8 22 5.7 0.1 4.7 1 1 3 4 4 4 0 HEAT-like repeat ThrE PF06738.12 EAX79582.1 - 0.021 14.2 4.4 0.026 13.9 4.4 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF1761 PF08570.10 EAX79582.1 - 0.054 13.8 6.6 0.065 13.5 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF2798 PF11391.8 EAX79582.1 - 1.1 9.3 18.6 3.4 7.8 18.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Cytochrome-c551 PF10643.9 EAX79582.1 - 1.1 8.7 6.2 1.3 8.5 6.2 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 AAA_lid_5 PF17865.1 EAX79582.1 - 5.5 7.1 11.1 3.7e+02 1.3 11.1 2.6 1 1 0 1 1 1 0 Midasin AAA lid domain PapD_N PF00345.20 EAX79583.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79583.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2897 PF11446.8 EAX79585.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Amidase02_C PF12123.8 EAX79586.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX79587.1 - 2.9e-06 27.8 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79587.1 - 0.013 15.3 0.4 0.064 13.1 0.2 2.3 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX79587.1 - 0.21 11.1 0.6 2.4 7.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4108 PF13390.6 EAX79589.1 - 1.3e-58 197.0 5.0 1.4e-58 196.8 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79589.1 - 0.087 13.1 0.1 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide IKKbetaNEMObind PF12179.8 EAX79590.1 - 0.18 11.8 0.1 0.46 10.6 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PTR PF12789.7 EAX79591.1 - 5.8e-31 106.4 10.5 5.8e-31 106.4 10.5 3.6 5 0 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX79591.1 - 0.032 14.0 0.1 0.093 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX79591.1 - 7.5 6.5 9.0 2.3 8.1 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF563 PF04577.14 EAX79592.1 - 5e-16 59.5 0.1 6.2e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CH PF00307.31 EAX79593.1 - 0.11 12.7 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain Pox_A32 PF04665.12 EAX79594.1 - 9.7e-07 28.5 2.8 9.7e-07 28.5 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79594.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79594.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79594.1 - 0.00011 22.3 2.7 0.00026 21.1 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79594.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79594.1 - 0.0012 18.7 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79594.1 - 0.0018 18.0 0.3 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79594.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX79594.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX79594.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79594.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79594.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79594.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Mid2 PF04478.12 EAX79595.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX79595.1 - 0.035 14.2 4.7 0.072 13.2 4.7 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M8 PF01457.16 EAX79595.1 - 0.12 11.0 0.5 0.43 9.2 0.0 1.8 2 0 0 2 2 2 0 Leishmanolysin Protocadherin PF08374.11 EAX79595.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.5 2 0 0 2 2 2 0 Protocadherin KilA-N PF04383.13 EAX79596.1 - 4.1e-08 33.1 0.1 4.9e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain PapD_N PF00345.20 EAX79598.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79598.1 - 0.058 13.4 0.4 0.086 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX79598.1 - 0.092 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX79600.1 - 5.9e-39 132.4 0.5 1.3e-38 131.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79600.1 - 0.0044 17.6 0.1 0.012 16.2 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family PTR PF12789.7 EAX79601.1 - 2.5e-10 40.2 6.3 1.5e-08 34.6 1.4 5.0 4 2 1 5 5 5 2 Phage tail repeat like DUF480 PF04337.12 EAX79601.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF480 DUF4795 PF16043.5 EAX79601.1 - 0.65 9.6 22.3 0.057 13.0 2.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF4107 PF13389.6 EAX79604.1 - 1.2e-72 243.4 4.1 1.4e-72 243.1 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX79606.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX79608.1 - 0.037 14.5 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX79608.1 - 0.25 11.4 3.6 6.7 6.8 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4116 PF13475.6 EAX79609.1 - 0.029 14.1 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX79610.1 - 1.8e-78 263.4 10.6 2.3e-78 263.0 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79610.1 - 0.16 11.9 1.4 0.62 9.9 0.8 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Alpha_adaptin_C PF02296.16 EAX79611.1 - 8.3e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain B2-adapt-app_C PF09066.10 EAX79611.1 - 0.063 13.4 0.2 15 5.7 0.1 2.7 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain Coatamer_beta_C PF07718.12 EAX79611.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Coatomer beta C-terminal region DUF3839 PF12943.7 EAX79612.1 - 5e-117 389.6 5.5 5.9e-117 389.4 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX79612.1 - 0.04 14.1 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF4107 PF13389.6 EAX79613.1 - 1e-56 191.6 1.6 1.4e-56 191.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Myb_DNA-binding PF00249.31 EAX79614.1 - 1e-28 99.3 1.6 2.4e-13 50.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX79614.1 - 3.2e-27 94.6 1.1 6.5e-16 58.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX79614.1 - 0.0014 18.5 0.1 0.037 13.9 0.0 2.9 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX79614.1 - 0.0051 16.8 0.1 0.63 10.1 0.0 2.4 1 1 1 2 2 2 1 SLIDE DUF4167 PF13763.6 EAX79614.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) Myb_DNA-bind_4 PF13837.6 EAX79614.1 - 0.014 15.7 1.0 0.69 10.3 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX79614.1 - 0.03 14.5 0.3 0.64 10.2 0.2 2.6 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-binding PF00249.31 EAX79615.1 - 8.5e-27 93.1 2.0 7.9e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX79615.1 - 2.8e-25 88.3 1.6 4.4e-14 52.5 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX79615.1 - 0.00087 19.1 0.2 0.037 13.9 0.0 3.0 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX79615.1 - 0.0038 17.3 0.2 0.63 10.1 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_2 PF08914.11 EAX79615.1 - 0.0066 16.6 0.5 0.13 12.5 0.4 2.5 2 1 0 2 2 2 1 Rap1 Myb domain DUF4167 PF13763.6 EAX79615.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) Myb_DNA-bind_4 PF13837.6 EAX79615.1 - 0.07 13.5 1.3 2.8 8.4 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4108 PF13390.6 EAX79616.1 - 1.1e-61 206.9 8.3 1.3e-61 206.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF1493 PF07377.12 EAX79617.1 - 0.042 14.3 0.2 0.07 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX79617.1 - 0.23 11.5 3.2 6.6 6.9 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX79618.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Herpes_IE2_3 PF03361.14 EAX79621.1 - 0.0045 16.9 1.0 0.29 11.0 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX79621.1 - 0.011 16.0 4.4 1.4 9.3 1.3 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region YlbD_coat PF14071.6 EAX79621.1 - 0.074 13.3 1.8 2.4 8.5 0.4 2.1 2 0 0 2 2 2 0 Putative coat protein DUF3839 PF12943.7 EAX79623.1 - 1.3e-62 211.4 3.6 1.4e-62 211.3 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAX79624.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79624.1 - 0.086 12.8 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2486 PF10667.9 EAX79626.1 - 3.2 7.9 16.2 6.1 7.0 16.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2486) Senescence PF06911.12 EAX79627.1 - 0.0074 16.6 1.0 0.045 14.1 0.1 2.1 2 0 0 2 2 2 1 Senescence-associated protein PTR PF12789.7 EAX79628.1 - 1.2e-05 25.3 0.6 1.2e-05 25.3 0.6 2.6 3 0 0 3 3 3 1 Phage tail repeat like YmaF PF12788.7 EAX79628.1 - 0.63 10.6 3.8 7.6 7.1 1.8 2.8 2 1 0 2 2 2 0 YmaF family Pox_A32 PF04665.12 EAX79629.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79629.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79629.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79629.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79629.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79629.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79629.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79629.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79629.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79629.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79629.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79629.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PapD_N PF00345.20 EAX79632.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1493 PF07377.12 EAX79633.1 - 0.041 14.3 0.2 0.089 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79634.1 - 0.036 14.6 5.1 9.2 7.5 0.1 3.4 3 1 0 3 3 3 0 TMP repeat Ribosomal_60s PF00428.19 EAX79635.1 - 0.059 14.0 0.4 0.08 13.5 0.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein HTH_32 PF13565.6 EAX79636.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DNA_pol_B_2 PF03175.13 EAX79638.1 - 6.7e-11 41.7 7.8 9.3e-11 41.3 4.3 2.0 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX79638.1 - 0.095 12.2 0.7 0.19 11.3 0.6 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX79638.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF3839 PF12943.7 EAX79639.1 - 3.7e-127 422.8 8.4 4.2e-127 422.6 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX79639.1 - 0.095 12.4 2.8 1.1 8.9 0.8 2.5 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit Rx_N PF18052.1 EAX79639.1 - 0.39 11.0 4.7 2.4 8.5 0.1 3.0 2 1 0 2 2 2 0 Rx N-terminal domain DUF3839 PF12943.7 EAX79640.1 - 3.1e-57 193.8 6.1 4.1e-57 193.4 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79640.1 - 0.031 14.7 0.2 0.036 14.5 0.2 1.1 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX79640.1 - 0.062 13.9 0.5 0.077 13.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX79640.1 - 0.2 12.1 1.0 0.5 10.9 0.7 2.0 2 1 0 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 EAX79640.1 - 0.36 10.9 4.2 1.5 9.0 2.0 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase T5orf172 PF10544.9 EAX79641.1 - 4.2e-05 24.0 0.1 0.00011 22.7 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79641.1 - 0.041 13.4 0.6 0.21 11.1 0.2 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF1031 PF06275.11 EAX79642.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX79642.1 - 0.12 12.5 0.3 0.61 10.2 0.2 2.2 1 1 1 2 2 2 0 Annexin KilA-N PF04383.13 EAX79643.1 - 9.2e-12 44.8 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain EssA PF10661.9 EAX79643.1 - 3.9 7.3 8.7 13 5.6 8.7 1.8 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA TMEM154 PF15102.6 EAX79644.1 - 2.8 7.9 7.9 3.3 7.6 7.9 1.1 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.11 EAX79644.1 - 2.8 6.0 16.2 3 5.9 16.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 KilA-N PF04383.13 EAX79645.1 - 1.8e-33 114.7 1.7 2e-33 114.6 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79645.1 - 0.022 15.3 0.0 0.074 13.7 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX79645.1 - 0.36 10.8 4.6 1.9 8.5 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX79646.1 - 1.7e-06 28.5 0.6 5.2e-06 26.9 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain VirE PF05272.11 EAX79647.1 - 1e-05 25.4 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX79647.1 - 0.058 13.8 0.4 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF5445 PF17520.2 EAX79649.1 - 9.1 6.2 22.1 11 5.9 5.4 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5445) DUF3839 PF12943.7 EAX79650.1 - 1.2e-142 473.5 10.1 1.5e-142 473.2 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX79650.1 - 0.16 12.4 1.6 4.5 7.8 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX79650.1 - 8.4 6.9 8.2 4.3 7.9 0.5 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX79651.1 - 6.5e-40 135.5 0.9 1.4e-39 134.4 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79651.1 - 0.0054 17.3 0.3 0.017 15.7 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family T5orf172 PF10544.9 EAX79652.1 - 0.00081 19.9 0.2 0.0022 18.5 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79652.1 - 0.0019 17.8 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain IstB_IS21 PF01695.17 EAX79654.1 - 2.5e-05 24.1 0.2 0.31 10.8 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX79654.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX79654.1 - 7.4e-05 22.3 2.3 7.4e-05 22.3 2.3 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein ResIII PF04851.15 EAX79654.1 - 0.00031 20.8 4.6 0.0006 19.8 4.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79654.1 - 0.00059 19.7 0.1 0.0012 18.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79654.1 - 0.0014 18.4 0.7 0.005 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79654.1 - 0.0046 16.6 2.1 0.013 15.1 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79654.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX79654.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79654.1 - 0.09 13.2 0.6 0.7 10.3 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79654.1 - 0.092 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79654.1 - 1.2 9.5 5.9 11 6.4 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX79654.1 - 4.7 7.9 11.3 0.31 11.7 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Pkinase PF00069.25 EAX79655.1 - 1.1e-26 93.8 0.0 1.3e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX79655.1 - 1e-14 54.5 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GPI PF06560.11 EAX79655.1 - 0.06 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) CbtA_toxin PF06755.12 EAX79655.1 - 0.13 12.3 0.1 9.7 6.3 0.0 2.2 2 0 0 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system Prp18 PF02840.15 EAX79656.1 - 1.4e-34 119.2 2.6 5.6e-33 114.0 0.0 2.0 2 0 0 2 2 2 2 Prp18 domain PAP_central PF04928.17 EAX79656.1 - 2 7.3 5.2 0.84 8.6 0.1 2.2 1 1 1 2 2 2 0 Poly(A) polymerase central domain ResIII PF04851.15 EAX79657.1 - 5.8e-05 23.2 4.0 0.00013 22.0 4.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79657.1 - 0.00029 20.7 0.0 0.0004 20.2 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79657.1 - 0.00032 21.0 0.0 0.00055 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79657.1 - 0.00054 19.8 0.1 0.001 18.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79657.1 - 0.0063 16.9 0.0 0.0093 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79657.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX79657.1 - 0.065 12.9 0.7 0.085 12.5 0.4 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF4588 PF15251.6 EAX79657.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX79657.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX79657.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79657.1 - 0.42 10.9 4.6 4.8 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX79657.1 - 0.62 10.5 3.8 0.3 11.5 0.8 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3417 PF11897.8 EAX79658.1 - 0.1 13.1 0.4 0.19 12.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF4108 PF13390.6 EAX79659.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX79661.1 - 8e-51 172.4 1.1 1.1e-50 172.0 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX79662.1 - 0.0081 16.6 0.4 0.015 15.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DUF2939 PF11159.8 EAX79663.1 - 0.013 15.9 0.3 0.015 15.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX79663.1 - 1.2 9.8 5.3 3.2 8.4 5.2 1.6 1 1 1 2 2 2 0 Homeodomain-like domain FAS_N PF17828.1 EAX79664.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX79666.1 - 6.5e-05 23.3 3.0 0.00037 20.9 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX79667.1 - 2.2e-62 209.2 5.3 2.4e-62 209.1 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) NAD_binding_8 PF13450.6 EAX79671.1 - 0.068 13.4 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1493 PF07377.12 EAX79672.1 - 0.047 14.2 0.3 0.11 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79673.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79674.1 - 0.067 13.1 0.8 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX79675.1 - 1.5e-25 88.9 6.0 1.5e-25 88.9 6.0 3.8 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX79675.1 - 1.9e-10 41.2 1.0 2.4e-06 28.1 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX79675.1 - 2.5e-09 37.2 0.4 2.8e-07 30.7 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX79675.1 - 2.9e-08 33.8 0.1 1.9e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX79675.1 - 2.5e-06 27.9 1.8 0.0014 19.2 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX79675.1 - 0.00013 22.1 3.6 0.0039 17.6 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeat DDE_Tnp_4 PF13359.6 EAX79676.1 - 6.7e-17 61.6 0.0 8.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX79676.1 - 4.8e-07 29.6 0.0 6.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 EAX79676.1 - 0.053 13.9 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Pox_A32 PF04665.12 EAX79677.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79677.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79677.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79677.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX79678.1 - 5.1e-43 145.5 0.4 1.1e-42 144.4 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX79679.1 - 1.7e-152 505.7 11.3 2.2e-152 505.4 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX79680.1 - 6e-56 189.6 3.9 6.8e-56 189.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MvaI_BcnI PF15515.6 EAX79680.1 - 0.069 13.0 0.7 3.2 7.5 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family IL7 PF01415.16 EAX79681.1 - 0.047 13.7 0.1 0.05 13.6 0.1 1.0 1 0 0 1 1 1 0 Interleukin 7/9 family KilA-N PF04383.13 EAX79682.1 - 8.7e-23 80.3 0.5 2e-22 79.1 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF4108 PF13390.6 EAX79683.1 - 8.5e-62 207.3 8.3 9.4e-62 207.2 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79683.1 - 0.11 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4108 PF13390.6 EAX79684.1 - 4.7e-61 204.9 8.5 5.2e-61 204.8 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79684.1 - 0.11 12.7 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide IstB_IS21 PF01695.17 EAX79685.1 - 2.5e-05 24.1 0.3 0.29 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX79685.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX79685.1 - 6.2e-05 22.6 2.2 6.2e-05 22.6 2.2 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX79685.1 - 0.00029 20.9 4.5 0.0005 20.1 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79685.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79685.1 - 0.0022 17.8 1.5 0.0036 17.1 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79685.1 - 0.004 16.8 2.7 0.014 15.0 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79685.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX79685.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79685.1 - 0.075 13.5 0.1 0.7 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79685.1 - 0.093 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX79685.1 - 0.13 12.3 0.8 1.7 8.7 0.8 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX79685.1 - 0.49 10.7 4.4 9.3 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX79685.1 - 1.8 9.3 11.2 0.12 13.0 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 GGDEF PF00990.21 EAX79686.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Peptidase_S49_N PF08496.10 EAX79686.1 - 7.1 6.7 7.9 8.1 6.5 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4108 PF13390.6 EAX79687.1 - 1.8e-59 199.8 5.2 2e-59 199.7 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79687.1 - 0.1 12.8 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX79688.1 - 1.1e-41 141.2 0.5 2.2e-41 140.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79688.1 - 0.01 16.4 0.1 0.03 15.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family HTH_7 PF02796.15 EAX79690.1 - 0.00083 19.4 0.4 0.0016 18.5 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EAX79690.1 - 0.0025 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EAX79690.1 - 0.0078 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Phage_AlpA PF05930.12 EAX79690.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Cadherin_2 PF08266.12 EAX79690.1 - 0.13 12.1 0.1 16 5.4 0.0 2.2 1 1 1 2 2 2 0 Cadherin-like DNA_pol_B_2 PF03175.13 EAX79692.1 - 1.2e-37 129.9 15.3 6.8e-37 127.4 15.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX79693.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX79693.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX79693.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX79693.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 T5orf172 PF10544.9 EAX79694.1 - 8.4e-07 29.5 0.7 1.9e-06 28.3 0.2 1.8 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX79694.1 - 0.0015 18.3 0.1 0.0091 15.8 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain DUF4106 PF13388.6 EAX79695.1 - 1e-97 328.0 5.4 1.2e-97 327.8 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF433 PF04255.14 EAX79696.1 - 0.012 15.5 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF433) GerE PF00196.19 EAX79696.1 - 0.17 11.5 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Pox_A32 PF04665.12 EAX79697.1 - 1.6e-07 31.1 2.9 2.3e-07 30.5 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79697.1 - 0.003 17.2 0.2 0.0037 16.9 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79697.1 - 0.044 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79697.1 - 0.051 13.3 0.2 0.23 11.2 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79697.1 - 0.056 13.2 0.1 0.079 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX79697.1 - 0.54 10.5 8.6 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) ATP_Ca_trans_C PF12424.8 EAX79699.1 - 0.04 14.4 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal GPS2_interact PF15784.5 EAX79700.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79700.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX79701.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX79702.1 - 0.093 13.2 0.5 0.2 12.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX79702.1 - 0.32 11.1 2.3 11 6.2 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX79703.1 - 2.4e-34 117.2 20.0 5.2e-33 112.9 14.2 4.1 3 2 1 4 4 4 2 Phage tail repeat like DUF4404 PF14357.6 EAX79703.1 - 9.1 7.0 7.9 8.1 7.2 0.3 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) DUF3467 PF11950.8 EAX79704.1 - 0.14 12.4 1.4 2 8.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DUF3574 PF12098.8 EAX79704.1 - 0.2 11.5 1.3 0.25 11.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) UPF0175 PF03683.13 EAX79705.1 - 0.076 12.7 0.0 5.7 6.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) KilA-N PF04383.13 EAX79706.1 - 8.7e-36 122.2 0.3 2.1e-35 121.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79706.1 - 0.01 16.4 0.1 0.028 15.0 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX79706.1 - 0.33 11.0 4.4 3.3 7.8 0.4 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX79707.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79707.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79707.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79707.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79707.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX79707.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX79708.1 - 1.2e-66 220.6 49.7 1.6e-33 114.6 14.8 6.4 4 2 3 7 7 6 3 Phage tail repeat like Pox_A32 PF04665.12 EAX79709.1 - 4e-07 29.8 0.1 4.6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1493 PF07377.12 EAX79710.1 - 0.039 14.4 0.5 0.087 13.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX79711.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX79712.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX79713.1 - 0.00034 21.1 0.2 0.0008 19.9 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79713.1 - 0.023 14.3 1.3 0.25 10.9 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX79713.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX79714.1 - 1.4e-150 499.5 15.1 1.7e-150 499.2 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79714.1 - 0.066 13.5 0.2 2.4 8.5 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX79714.1 - 0.23 11.3 1.4 0.91 9.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79714.1 - 0.61 10.6 4.8 6.7 7.2 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX79714.1 - 2.6 8.4 6.8 10 6.5 0.1 3.9 4 1 0 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX79715.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX79716.1 - 1.5e-126 420.8 6.3 1.7e-126 420.6 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79716.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Ank_2 PF12796.7 EAX79718.1 - 2.4e-06 28.0 0.0 0.0077 16.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX79718.1 - 0.00069 20.1 0.0 1.1 9.9 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX79718.1 - 0.0012 19.1 0.0 1.3 9.8 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 EAX79718.1 - 0.0036 17.2 2.6 0.0036 17.2 2.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX79718.1 - 0.1 13.1 0.0 14 6.3 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat T5orf172 PF10544.9 EAX79720.1 - 5.3e-06 26.9 0.3 1.3e-05 25.6 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX79721.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79721.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79721.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79721.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79721.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79721.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX79721.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX79721.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79721.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79721.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79721.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79721.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) HNH_3 PF13392.6 EAX79722.1 - 4.5e-07 29.5 0.3 4.5e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 HNH endonuclease Mito_fiss_reg PF05308.11 EAX79723.1 - 0.1 12.7 0.6 0.1 12.6 0.6 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX79723.1 - 0.32 10.5 2.3 0.32 10.5 2.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3839 PF12943.7 EAX79724.1 - 1.3e-155 515.9 12.4 1.6e-155 515.6 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX79724.1 - 0.11 12.8 0.6 1.2 9.5 0.1 2.8 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX79724.1 - 0.13 12.1 0.5 0.32 10.9 0.2 1.7 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX79725.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Imm70 PF15601.6 EAX79727.1 - 3.5 7.2 45.3 29 4.2 0.2 11.6 1 1 17 18 18 18 0 Immunity protein 70 Cnd1 PF12717.7 EAX79728.1 - 6.2e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX79728.1 - 1.1e-05 25.3 0.0 0.001 19.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EAX79728.1 - 1.7e-05 25.1 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EAX79728.1 - 0.004 17.7 0.0 0.0088 16.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAX79728.1 - 0.0063 17.0 0.0 6.5 7.4 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat Cohesin_HEAT PF12765.7 EAX79728.1 - 0.024 14.9 0.1 0.29 11.5 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 EAX79728.1 - 0.13 10.8 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region DUF4107 PF13389.6 EAX79729.1 - 2.4e-58 196.9 12.3 2.4e-32 112.3 1.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79729.1 - 0.1 13.0 0.6 0.13 12.6 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta P22_AR_C PF10548.9 EAX79730.1 - 0.059 13.6 0.1 14 6.0 0.0 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX79730.1 - 0.11 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin DUF4108 PF13390.6 EAX79733.1 - 3.1e-61 205.5 8.1 3.4e-61 205.3 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79734.1 - 2.4e-157 521.6 12.2 3e-157 521.3 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX79734.1 - 0.025 14.9 0.2 16 5.9 0.0 3.7 3 0 0 3 3 3 0 Tup N-terminal DUF29 PF01724.16 EAX79734.1 - 0.064 13.5 0.7 0.16 12.2 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX79734.1 - 0.24 11.9 2.9 2.1 8.9 0.1 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ly49 PF08391.10 EAX79735.1 - 0.24 11.8 1.8 0.28 11.5 1.8 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX79735.1 - 0.43 10.5 2.7 0.79 9.7 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DNA_pol_B_2 PF03175.13 EAX79736.1 - 3.7e-09 36.0 1.5 5.3e-09 35.5 0.8 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79736.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX79736.1 - 0.15 10.8 1.9 2.1 7.0 1.9 2.3 1 1 0 1 1 1 0 DNA polymerase family B PapD_N PF00345.20 EAX79737.1 - 0.03 14.2 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX79737.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX79738.1 - 5.3e-40 137.4 3.9 7.2e-40 137.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX79739.1 - 3.6e-35 120.2 0.7 7.1e-35 119.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79739.1 - 0.025 15.2 0.0 0.074 13.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX79740.1 - 4.3e-25 88.6 5.0 6.2e-25 88.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX79740.1 - 0.12 11.5 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Glycos_transf_1 PF00534.20 EAX79744.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF4107 PF13389.6 EAX79745.1 - 2.4e-72 242.4 4.9 2.8e-72 242.2 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79745.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX79745.1 - 0.17 10.2 1.1 0.25 9.7 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX79746.1 - 1.1e-82 272.0 58.4 1.3e-34 118.1 16.2 5.8 4 2 3 7 7 6 3 Phage tail repeat like DUF4116 PF13475.6 EAX79746.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX79746.1 - 0.43 10.0 4.1 1.6 8.2 0.6 2.3 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF2785 PF10978.8 EAX79746.1 - 4 7.2 7.4 1.8 8.3 3.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2785) DUF2897 PF11446.8 EAX79747.1 - 1.1 9.2 3.8 2.4 8.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX79748.1 - 2.2e-06 27.3 0.8 2.4e-06 27.2 0.8 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX79748.1 - 0.0027 16.6 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX79748.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX79748.1 - 0.022 14.7 0.7 0.047 13.7 0.6 1.6 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IstB_IS21 PF01695.17 EAX79748.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79748.1 - 0.085 12.8 0.2 0.39 10.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3783) PPIP5K2_N PF18086.1 EAX79748.1 - 0.22 11.7 1.8 1.7 8.9 0.1 2.5 1 1 2 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain DUF4107 PF13389.6 EAX79750.1 - 1.1e-73 246.8 4.7 1.4e-73 246.4 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX79750.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1476 PF07345.11 EAX79750.1 - 0.2 12.0 1.3 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX79751.1 - 0 1085.9 259.3 6.6e-31 106.2 14.4 9.4 2 2 12 14 14 14 13 Phage tail repeat like DUF4116 PF13475.6 EAX79751.1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Tis11B_N PF04553.12 EAX79751.1 - 0.51 10.9 9.4 10 6.7 0.5 4.2 1 1 2 3 3 3 0 Tis11B like protein, N terminus DUF2785 PF10978.8 EAX79751.1 - 1.3 8.7 18.8 5.7 6.7 4.1 4.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) DUF3839 PF12943.7 EAX79752.1 - 2.2e-99 331.9 7.2 2.4e-99 331.7 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX79752.1 - 0.044 13.3 0.3 0.05 13.1 0.3 1.1 1 0 0 1 1 1 0 Z1 domain LRR_5 PF13306.6 EAX79753.1 - 1.5e-24 86.4 7.8 8.8e-17 61.3 3.4 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX79753.1 - 0.015 15.1 0.0 21 5.0 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat DNA_pol_B_2 PF03175.13 EAX79754.1 - 1.3e-30 106.7 12.6 5.7e-30 104.6 12.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX79755.1 - 4.5e-157 520.7 16.0 5.5e-157 520.4 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX79755.1 - 0.11 12.9 0.3 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79755.1 - 1.8 9.1 7.4 2.3 8.8 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX79756.1 - 1.5e-156 519.0 14.4 1.8e-156 518.7 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79756.1 - 0.058 13.9 1.6 0.1 13.0 0.3 1.9 2 0 0 2 2 2 0 Fez1 DUF5398 PF17376.2 EAX79756.1 - 0.096 13.3 1.2 0.99 10.1 0.1 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5398) NTP_transf_6 PF06042.11 EAX79756.1 - 0.19 11.6 1.8 0.52 10.2 0.5 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX79756.1 - 0.84 10.1 7.7 2.1 8.9 0.9 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX79757.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEAD PF00270.29 EAX79759.1 - 6.5e-08 32.5 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX79759.1 - 8.6e-07 29.3 6.9 1.2e-05 25.6 3.9 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX79759.1 - 1.7e-06 28.1 3.5 5.1e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4106 PF13388.6 EAX79760.1 - 1.1e-203 677.1 15.2 1.2e-203 677.0 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX79760.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX79760.1 - 1 9.3 15.7 1.3 8.9 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF737 PF05300.11 EAX79760.1 - 2.3 8.5 12.0 5.3 7.3 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF4108 PF13390.6 EAX79761.1 - 2.7e-57 192.7 5.1 3e-57 192.6 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX79762.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX79762.1 - 9.8 6.1 6.6 20 5.2 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX79763.1 - 2.2e-05 24.6 1.1 3.7e-05 23.8 1.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79763.1 - 0.00028 20.7 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79763.1 - 0.00038 20.8 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79763.1 - 0.0014 18.5 0.1 0.002 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79763.1 - 0.0062 16.9 0.0 0.008 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79763.1 - 0.03 13.8 0.1 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX79763.1 - 0.058 13.1 0.6 0.086 12.5 0.2 1.5 1 1 1 2 2 2 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX79763.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX79763.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX79763.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX79763.1 - 0.28 10.7 3.4 0.098 12.2 1.0 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase APG12 PF04110.13 EAX79763.1 - 0.57 10.6 3.0 0.45 11.0 0.4 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PapD_N PF00345.20 EAX79765.1 - 0.031 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX79765.1 - 0.063 13.3 0.6 0.088 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX79766.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX79766.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX79766.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX79766.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sulfatase PF00884.23 EAX79767.1 - 1.4e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EAX79767.1 - 0.0043 15.7 0.0 0.054 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DNA_pol_B_2 PF03175.13 EAX79768.1 - 7.3e-09 35.0 1.1 1.4e-08 34.1 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX79768.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX79768.1 - 0.15 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX79769.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Spo12 PF05032.12 EAX79770.1 - 0.52 10.3 8.3 0.18 11.7 2.9 2.5 3 0 0 3 3 3 0 Spo12 family PTR PF12789.7 EAX79771.1 - 1e-30 105.5 10.7 1e-30 105.5 10.7 4.2 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX79771.1 - 0.017 14.9 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Gp5_C PF06715.12 EAX79771.1 - 0.074 13.2 2.2 7.1 7.0 0.2 4.1 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) YmaF PF12788.7 EAX79771.1 - 0.25 11.9 16.2 1.1 9.8 0.3 3.7 2 2 0 3 3 3 0 YmaF family DUF240 PF03086.14 EAX79771.1 - 1.1 9.2 6.7 1.2 9.1 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) TbpB_A PF17484.2 EAX79771.1 - 5.2 7.8 7.7 16 6.3 6.7 2.4 2 2 0 2 2 2 0 N-Lobe handle Tf-binding protein B Cas_St_Csn2 PF16813.5 EAX79772.1 - 0.037 13.1 0.6 0.037 13.1 0.6 1.6 2 0 0 2 2 2 0 CRISPR-associated protein Csn2 subfamily St YmaF PF12788.7 EAX79773.1 - 0.11 13.1 1.4 1.3 9.6 1.4 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX79773.1 - 0.61 10.4 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX79774.1 - 1.5e-06 28.1 1.2 2.5e-06 27.4 0.4 1.7 2 0 0 2 2 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX79775.1 - 0.0073 16.0 0.8 0.021 14.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX79779.1 - 1.1e-29 103.7 4.7 6e-28 98.0 4.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Meiosis_expr PF15163.6 EAX79781.1 - 0.022 15.4 0.6 0.035 14.8 0.2 1.5 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX79781.1 - 0.17 11.7 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX79781.1 - 1.6 8.7 9.8 0.14 12.0 2.8 2.8 4 1 0 4 4 4 0 Spo12 family Polysacc_deac_1 PF01522.21 EAX79782.1 - 0.01 15.7 0.4 0.011 15.6 0.4 1.0 1 0 0 1 1 1 0 Polysaccharide deacetylase FliD_N PF02465.18 EAX79783.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX79783.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YvrJ PF12841.7 EAX79784.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Pox_A32 PF04665.12 EAX79786.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79786.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79786.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79786.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79786.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79786.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79786.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX79790.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX79790.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX79790.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain T5orf172 PF10544.9 EAX79791.1 - 7.5e-07 29.6 0.2 2.2e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79791.1 - 0.014 15.0 1.2 0.12 11.9 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX79791.1 - 0.023 14.5 1.9 0.074 12.9 0.5 2.4 2 2 0 2 2 2 0 KilA-N domain DDR PF08841.10 EAX79792.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX79792.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4107 PF13389.6 EAX79793.1 - 1.6e-66 223.4 13.0 8.4e-65 217.9 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX79794.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79794.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79794.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79794.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79794.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79794.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX79795.1 - 5e-80 268.5 12.0 6.5e-80 268.1 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX79795.1 - 0.056 13.0 0.6 0.24 10.9 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX79796.1 - 1.6e-154 512.3 11.7 2.1e-154 512.0 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79796.1 - 0.033 14.6 1.9 0.17 12.3 0.4 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX79796.1 - 0.04 14.2 1.5 14 6.0 0.1 3.8 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX79796.1 - 0.13 12.8 5.7 1.1 9.7 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4168 PF13767.6 EAX79796.1 - 0.29 12.3 3.3 15 6.9 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF2408 PF10303.9 EAX79796.1 - 0.9 10.1 6.5 0.24 12.0 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) EF-hand_10 PF14788.6 EAX79798.1 - 0.006 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 EF hand FliD_C PF07195.12 EAX79798.1 - 0.093 12.1 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Ank_4 PF13637.6 EAX79800.1 - 4.7e-27 94.0 1.4 1.3e-11 44.7 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX79800.1 - 2.4e-23 82.5 7.9 3.2e-13 50.1 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX79800.1 - 5.2e-22 77.3 10.9 1.5e-08 34.7 0.1 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX79800.1 - 1.3e-19 68.2 1.9 1.3e-06 28.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX79800.1 - 3.2e-16 59.2 8.1 2.6e-10 40.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) BAT PF15915.5 EAX79800.1 - 0.0032 17.4 0.1 0.0099 15.8 0.1 1.8 1 1 0 1 1 1 1 GAF and HTH_10 associated domain DHquinase_II PF01220.19 EAX79800.1 - 0.012 15.3 2.5 0.03 14.0 2.4 1.8 1 1 0 1 1 1 0 Dehydroquinase class II DUF3895 PF13034.6 EAX79800.1 - 0.02 14.9 1.8 4.6 7.3 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3895) Aldolase PF01081.19 EAX79800.1 - 0.032 13.6 0.3 0.046 13.1 0.3 1.3 1 1 0 1 1 1 0 KDPG and KHG aldolase Alpha-amylase_N PF02903.14 EAX79800.1 - 0.088 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain Tex_N PF09371.10 EAX79800.1 - 0.14 11.9 1.1 4 7.1 0.0 2.2 1 1 1 2 2 2 0 Tex-like protein N-terminal domain T5orf172 PF10544.9 EAX79801.1 - 1.4e-06 28.8 0.5 3.5e-06 27.5 0.5 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79801.1 - 0.01 15.4 0.7 0.13 11.7 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX79801.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX79802.1 - 3.2e-27 95.5 6.0 4.7e-27 95.0 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX79802.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr KilA-N PF04383.13 EAX79803.1 - 1.8e-34 118.0 0.8 3.7e-34 117.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX79803.1 - 0.29 11.9 2.2 18 6.1 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 T5orf172 PF10544.9 EAX79804.1 - 8.3e-07 29.5 0.1 2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79804.1 - 0.0073 16.2 1.1 0.043 13.7 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX79804.1 - 0.079 12.5 0.4 0.29 10.6 0.2 1.8 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX79805.1 - 3.5e-79 265.7 8.8 4.5e-79 265.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX79805.1 - 0.09 13.3 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX79808.1 - 0.037 14.5 0.6 0.069 13.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) RRM_9 PF18444.1 EAX79809.1 - 0.00027 20.7 2.8 12 5.9 0.0 4.0 1 1 3 4 4 4 3 RNA recognition motif Fungal_trans PF04082.18 EAX79809.1 - 7 5.6 17.1 1.8e+04 -7.3 17.1 3.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF3447 PF11929.8 EAX79810.1 - 1.4e-34 117.9 11.1 2.1e-34 117.3 5.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX79810.1 - 2e-05 25.1 0.2 0.0009 19.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX79810.1 - 0.11 13.1 0.1 1.3 9.7 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) PPV_E2_C PF00511.17 EAX79812.1 - 0.0097 16.1 0.6 0.45 10.7 0.1 2.6 1 1 1 2 2 2 1 E2 (early) protein, C terminal YL1 PF05764.13 EAX79812.1 - 0.019 15.1 8.0 0.029 14.5 8.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein WW_FCH_linker PF16623.5 EAX79812.1 - 0.091 13.5 11.2 3.8 8.3 1.0 3.7 1 1 2 3 3 3 0 Unstructured linker region between on GAS7 protein KAAG1 PF15354.6 EAX79812.1 - 0.96 10.0 6.7 1.8 9.2 2.1 2.4 1 1 1 2 2 2 0 Kidney-associated antigen 1 YmaF PF12788.7 EAX79813.1 - 0.17 12.4 1.6 2.3 8.8 1.7 2.0 1 1 0 1 1 1 0 YmaF family DUF4108 PF13390.6 EAX79814.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX79817.1 - 4.3e-07 29.6 3.0 4.3e-07 29.6 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79817.1 - 3.3e-05 24.2 0.3 0.00025 21.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79817.1 - 4.3e-05 23.3 0.3 0.35 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79817.1 - 0.00018 21.5 3.6 0.00034 20.7 3.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79817.1 - 0.00061 19.6 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX79817.1 - 0.0011 18.6 0.4 0.0062 16.2 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX79817.1 - 0.0013 18.6 0.7 0.0026 17.6 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79817.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX79817.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX79817.1 - 0.089 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX79817.1 - 0.092 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX79817.1 - 0.51 10.6 4.1 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX79818.1 - 7.2e-119 395.6 7.5 8.2e-119 395.4 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79818.1 - 0.019 14.8 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX79820.1 - 4.3e-33 114.8 1.7 6.3e-33 114.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ribosomal_S6e PF01092.19 EAX79821.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e DUF1043 PF06295.12 EAX79822.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2400 PF09674.10 EAX79822.1 - 0.015 15.3 0.5 0.02 14.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) KilA-N PF04383.13 EAX79823.1 - 7.2e-33 112.8 1.1 1.1e-32 112.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX79823.1 - 0.016 15.8 0.1 0.04 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DNA_pol_B_2 PF03175.13 EAX79824.1 - 1.4e-29 103.3 13.2 6.3e-29 101.2 13.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX79824.1 - 0.014 15.5 0.9 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) JMY PF15871.5 EAX79824.1 - 0.018 14.4 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX79825.1 - 1.3e-157 522.5 12.3 1.5e-157 522.3 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79825.1 - 0.081 13.4 1.1 0.55 10.6 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX79825.1 - 0.21 12.0 6.6 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX79825.1 - 3.4 8.0 7.2 9.5 6.6 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX79826.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX79826.1 - 0.032 13.5 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX79826.1 - 0.038 13.5 0.3 0.048 13.2 0.3 1.1 1 0 0 1 1 1 0 Legume lectin domain DUF3839 PF12943.7 EAX79827.1 - 3.5e-78 262.4 9.3 4.6e-78 262.0 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX79827.1 - 0.016 15.3 0.1 5.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TFIIA PF03153.13 EAX79828.1 - 1.9 8.4 20.2 2.4 8.1 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_D5 PF03288.16 EAX79829.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79829.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79829.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX79830.1 - 1.7e-63 212.9 5.6 1.8e-63 212.7 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX79831.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX79832.1 - 2.2e-05 24.5 0.2 2.8e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79832.1 - 0.00026 20.8 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79832.1 - 0.00069 19.9 0.0 0.00094 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79832.1 - 0.0018 18.1 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79832.1 - 0.0064 16.8 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79832.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX79832.1 - 0.068 12.9 0.0 0.085 12.6 0.0 1.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX79832.1 - 0.083 12.5 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX79832.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX79832.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain PTR PF12789.7 EAX79834.1 - 6.5e-17 61.3 1.0 6.5e-17 61.3 1.0 5.1 6 0 0 6 6 6 1 Phage tail repeat like DUF4795 PF16043.5 EAX79834.1 - 0.026 14.2 1.8 0.026 14.2 1.8 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX79834.1 - 0.027 14.2 0.1 0.11 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Gp5_C PF06715.12 EAX79834.1 - 0.038 14.1 0.3 2 8.8 0.3 3.3 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) YmaF PF12788.7 EAX79834.1 - 0.41 11.2 12.8 1.5 9.4 3.1 3.9 2 2 0 2 2 2 0 YmaF family Tox-REase-3 PF15647.6 EAX79835.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 CTU2 PF10288.9 EAX79836.1 - 0.041 14.1 0.9 0.076 13.3 0.9 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1289 PF06945.13 EAX79836.1 - 0.14 12.0 2.0 0.22 11.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) KilA-N PF04383.13 EAX79837.1 - 9.5e-30 102.7 0.9 1.9e-29 101.7 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX79837.1 - 0.02 15.1 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX79838.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79838.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79838.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79838.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4378 PF14309.6 EAX79839.1 - 0.031 14.7 0.1 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) DUF3839 PF12943.7 EAX79840.1 - 1.7e-78 263.5 10.2 2e-78 263.2 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX79840.1 - 0.15 11.9 1.3 0.66 9.8 1.3 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX79842.1 - 2e-157 521.9 14.9 2.5e-157 521.6 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79842.1 - 0.61 10.6 6.9 2.3 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX79843.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX79843.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DNA_pol_B_2 PF03175.13 EAX79844.1 - 2e-17 63.2 3.2 3.4e-17 62.5 3.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Parathyroid PF01279.17 EAX79845.1 - 0.038 14.6 0.1 0.08 13.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX79846.1 - 7.7e-06 25.5 1.9 7.7e-06 25.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX79846.1 - 3e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79846.1 - 3.9e-05 23.5 0.3 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX79846.1 - 0.00016 21.7 3.3 0.00035 20.6 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79846.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX79846.1 - 0.0018 18.0 0.5 0.013 15.1 0.2 2.2 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX79846.1 - 0.0018 18.1 0.7 0.0051 16.6 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79846.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX79846.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX79846.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX79846.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX79846.1 - 0.38 11.0 4.1 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2805 PF10985.8 EAX79846.1 - 0.45 10.9 4.1 0.77 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) ResIII PF04851.15 EAX79847.1 - 2.2e-05 24.5 0.2 2.8e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79847.1 - 0.00027 20.8 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79847.1 - 0.001 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79847.1 - 0.0018 18.2 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79847.1 - 0.0062 16.9 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX79847.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX79847.1 - 0.068 12.9 0.0 0.086 12.6 0.0 1.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX79847.1 - 0.079 12.5 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX79847.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX79847.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX79849.1 - 2.1e-62 209.3 5.7 2.3e-62 209.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Trypan_PARP PF05887.11 EAX79850.1 - 0.12 12.4 12.1 0.13 12.2 12.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX79850.1 - 3 8.3 7.2 3.5 8.1 7.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TALPID3 PF15324.6 EAX79850.1 - 5 4.7 16.7 5.6 4.5 16.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GPS2_interact PF15784.5 EAX79851.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX79851.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX79853.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat AAA_22 PF13401.6 EAX79855.1 - 5.4e-05 23.5 0.1 0.00032 21.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX79855.1 - 0.00011 22.3 3.5 0.00019 21.5 3.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79855.1 - 0.00035 20.4 0.0 0.00048 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX79855.1 - 0.00098 19.0 1.2 0.0032 17.3 1.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79855.1 - 0.0068 16.7 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79855.1 - 0.01 15.6 0.3 0.25 11.0 0.0 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX79855.1 - 0.043 13.3 0.1 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX79855.1 - 0.063 13.0 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX79855.1 - 0.1 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX79855.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79855.1 - 0.17 12.2 4.7 3.9 7.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX79855.1 - 1 9.8 4.6 0.38 11.2 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX79857.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX79859.1 - 1.7e-15 56.8 41.5 1.3e-08 34.8 3.9 5.1 6 0 0 6 6 6 3 Phage tail repeat like EpuA PF11772.8 EAX79859.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX79859.1 - 6 6.8 9.0 41 4.0 0.1 3.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4795 PF16043.5 EAX79859.1 - 9.3 5.8 18.5 13 5.3 10.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX79860.1 - 0.011 16.2 3.6 0.23 12.0 0.4 2.1 1 1 0 2 2 2 0 YmaF family Gp5_C PF06715.12 EAX79860.1 - 0.54 10.5 0.3 0.54 10.5 0.3 2.4 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Phage_fiber PF03335.13 EAX79860.1 - 2.3 8.6 9.5 7.7 7.0 1.5 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat PTR PF12789.7 EAX79861.1 - 5.7e-37 125.6 21.2 8.9e-32 108.9 11.3 3.9 4 1 1 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX79861.1 - 1 9.9 18.7 11 6.6 8.2 3.7 3 2 0 3 3 3 0 YmaF family DUF3839 PF12943.7 EAX79862.1 - 4.3e-40 137.7 4.5 6e-40 137.2 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX79862.1 - 0.065 13.7 0.5 0.57 10.7 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX79862.1 - 0.27 11.6 2.2 0.73 10.2 0.9 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Pox_A32 PF04665.12 EAX79863.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79863.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79863.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79863.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DDR PF08841.10 EAX79865.1 - 0.14 11.1 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX79867.1 - 8e-27 93.1 14.0 3.1e-23 81.6 7.0 4.3 5 1 0 5 5 5 2 Phage tail repeat like EDR1 PF14381.6 EAX79867.1 - 0.023 14.4 1.2 1.2 8.9 0.7 2.4 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX79867.1 - 0.038 14.4 3.2 0.039 14.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4116 PF13475.6 EAX79867.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX79867.1 - 0.27 11.8 13.8 0.4 11.2 1.9 3.8 3 1 0 3 3 3 0 YmaF family Pox_A32 PF04665.12 EAX79869.1 - 3.8e-08 33.1 1.1 4.6e-08 32.8 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79869.1 - 0.003 17.2 0.1 0.0033 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX79869.1 - 0.045 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX79869.1 - 0.09 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX79870.1 - 3.5e-155 514.5 13.3 4.3e-155 514.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX79870.1 - 0.36 11.3 6.1 1.9 9.0 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX79871.1 - 1.2e-37 129.9 16.9 6.1e-37 127.6 16.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX79871.1 - 0.15 12.0 0.1 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF5065 PF16723.5 EAX79871.1 - 0.16 12.0 0.9 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) PWI PF01480.17 EAX79872.1 - 0.032 14.6 0.1 0.048 14.0 0.1 1.2 1 0 0 1 1 1 0 PWI domain TIG PF01833.24 EAX79873.1 - 2.7e-06 27.4 0.0 6.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_M8 PF01457.16 EAX79873.1 - 0.0018 17.1 0.4 0.0026 16.5 0.4 1.2 1 0 0 1 1 1 1 Leishmanolysin DUF563 PF04577.14 EAX79874.1 - 1.1e-18 68.2 0.0 1.3e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pox_A32 PF04665.12 EAX79875.1 - 2e-07 30.8 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79875.1 - 0.0031 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79875.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79875.1 - 0.06 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX79875.1 - 0.41 10.8 8.5 5.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PTR PF12789.7 EAX79877.1 - 5.2e-06 26.4 0.5 5.2e-06 26.4 0.5 4.6 4 3 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX79877.1 - 0.0056 16.3 15.2 0.36 10.4 1.4 3.4 1 1 1 3 3 3 2 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX79877.1 - 0.01 16.3 0.6 1.9 9.1 0.1 3.1 3 0 0 3 3 3 0 YmaF family DUF2120 PF09893.9 EAX79877.1 - 0.96 9.5 3.4 6.2 6.9 0.3 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3978 PF13123.6 EAX79879.1 - 0.079 12.7 0.0 0.084 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) NurA PF09376.10 EAX79880.1 - 0.0098 15.6 0.6 0.012 15.3 0.6 1.2 1 0 0 1 1 1 1 NurA domain MetOD2 PF18548.1 EAX79880.1 - 0.032 14.3 6.9 0.036 14.2 1.1 2.6 2 1 0 2 2 2 0 Metanogen output domain 2 Citrate_bind PF16114.5 EAX79880.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding CENP-O PF09496.10 EAX79880.1 - 2.3 8.2 8.5 1.5 8.8 2.6 2.2 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component DUF3839 PF12943.7 EAX79882.1 - 4e-80 268.8 11.1 5.3e-80 268.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX79882.1 - 0.087 12.3 0.5 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX79883.1 - 9.2e-23 80.9 0.5 1e-22 80.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX79884.1 - 7.7e-148 490.5 11.4 1.1e-147 490.0 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX79884.1 - 0.001 19.6 0.4 0.0084 16.6 0.3 2.5 2 0 0 2 2 2 1 T5orf172 domain Fez1 PF06818.15 EAX79884.1 - 0.028 14.9 0.9 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Fez1 ATP-synt_F6 PF05511.11 EAX79884.1 - 0.17 12.3 1.2 35 4.9 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 KELK PF15796.5 EAX79884.1 - 0.25 11.8 5.7 0.92 10.0 0.7 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX79884.1 - 0.52 10.6 4.0 1.2 9.4 0.0 3.2 2 2 2 4 4 4 0 Rx N-terminal domain DUF3839 PF12943.7 EAX79885.1 - 4.8e-109 363.5 7.5 5.5e-109 363.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX79885.1 - 0.083 13.5 0.5 0.44 11.2 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX79886.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX79886.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX79887.1 - 2.9e-29 102.3 6.7 4.8e-29 101.5 6.7 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX79889.1 - 8.3e-18 64.2 1.9 8.3e-18 64.2 1.9 3.1 3 0 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX79889.1 - 0.13 12.1 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PG_binding_2 PF08823.11 EAX79890.1 - 0.023 15.0 0.1 0.07 13.5 0.1 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Alba PF01918.21 EAX79890.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 Alba TPR_20 PF14561.6 EAX79890.1 - 0.087 13.2 0.5 0.89 9.9 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Csm2_III-A PF03750.13 EAX79891.1 - 0.03 15.2 0.6 0.036 14.9 0.6 1.1 1 0 0 1 1 1 0 Csm2 Type III-A Spo12 PF05032.12 EAX79891.1 - 0.32 10.9 7.7 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX79892.1 - 1.3e-06 28.8 0.4 1.3e-05 25.7 0.3 2.3 2 1 0 2 2 2 1 T5orf172 domain DUF3148 PF11347.8 EAX79892.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Pox_A32 PF04665.12 EAX79893.1 - 1.7e-07 31.0 0.3 2e-07 30.7 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX79893.1 - 0.0069 15.3 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX79893.1 - 0.059 13.0 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX79893.1 - 0.064 13.2 0.3 0.53 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX79893.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) IstB_IS21 PF01695.17 EAX79893.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4108 PF13390.6 EAX79894.1 - 1.8e-62 209.5 4.8 2e-62 209.4 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX79896.1 - 2.8e-05 24.1 0.6 2.8e-05 24.1 0.6 4.8 5 1 1 6 6 6 1 Phage tail repeat like DUF3417 PF11897.8 EAX79896.1 - 0.16 12.4 3.2 0.31 11.5 0.0 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX79896.1 - 0.48 10.0 21.3 0.12 12.0 5.6 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX79896.1 - 1.4 8.7 8.7 2.3 7.9 8.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) KilA-N PF04383.13 EAX79897.1 - 6.8e-23 80.7 0.7 1.5e-22 79.6 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX79898.1 - 1.4e-06 28.8 0.2 3.4e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79898.1 - 0.071 12.6 0.4 1 8.9 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain FRG PF08867.11 EAX79898.1 - 0.14 13.1 0.0 5.9 7.9 0.0 2.3 2 0 0 2 2 2 0 FRG domain NPA PF16469.5 EAX79899.1 - 0.062 13.9 0.4 13 6.4 0.1 2.2 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 DUF1031 PF06275.11 EAX79899.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Pox_A32 PF04665.12 EAX79900.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79900.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79900.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79900.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79900.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79900.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79900.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PRA-PH PF01503.17 EAX79902.1 - 0.21 12.1 1.8 2 8.9 2.8 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase I-set PF07679.16 EAX79903.1 - 0.0013 18.8 0.5 0.012 15.7 0.1 3.0 3 1 1 4 4 4 1 Immunoglobulin I-set domain DUF3324 PF11797.8 EAX79903.1 - 0.023 14.7 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) SH3_2 PF07653.17 EAX79903.1 - 0.039 13.6 0.2 0.98 9.2 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain PBP PF01161.20 EAX79903.1 - 0.11 12.8 0.0 14 6.0 0.0 2.4 1 1 1 2 2 2 0 Phosphatidylethanolamine-binding protein Matrilin_ccoil PF10393.9 EAX79903.1 - 0.12 12.2 0.4 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Cupredoxin_1 PF13473.6 EAX79903.1 - 0.46 10.6 2.6 7.7 6.7 1.0 3.1 2 1 1 3 3 3 0 Cupredoxin-like domain DUF916 PF06030.12 EAX79903.1 - 0.5 10.4 0.0 0.5 10.4 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF916) DUF5067 PF16729.5 EAX79903.1 - 0.6 10.0 0.0 0.6 10.0 0.0 3.6 3 2 1 5 5 5 0 Domain of unknown function (DUF5067) HSCB_C PF07743.13 EAX79904.1 - 0.045 14.2 0.1 0.048 14.2 0.1 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF5446 PF17522.2 EAX79904.1 - 0.067 13.4 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5446) KilA-N PF04383.13 EAX79905.1 - 4.5e-41 139.2 0.3 1.4e-40 137.6 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain BRO1 PF03097.18 EAX79906.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX79906.1 - 5.5 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat PTR PF12789.7 EAX79907.1 - 2.5e-05 24.3 0.4 2.5e-05 24.3 0.4 4.2 3 1 0 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX79907.1 - 0.0051 16.7 5.8 0.0071 16.2 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX79907.1 - 0.028 14.1 0.1 0.093 12.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX79907.1 - 0.032 14.7 0.5 0.16 12.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX79907.1 - 0.051 13.3 0.1 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX79907.1 - 1.8 8.2 14.1 0.29 10.7 6.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Flavodoxin_2 PF02525.17 EAX79909.1 - 4.9e-15 55.8 0.5 1e-14 54.7 0.5 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX79909.1 - 0.0067 16.2 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 1 NADPH-dependent FMN reductase HTH_54 PF18607.1 EAX79909.1 - 0.043 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 ParA helix turn helix domain DUF3839 PF12943.7 EAX79910.1 - 2.2e-152 505.3 13.0 2.8e-152 505.0 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX79910.1 - 0.024 13.8 0.2 0.037 13.2 0.2 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II THOC7 PF05615.13 EAX79910.1 - 0.057 13.7 0.7 0.19 12.0 0.8 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 MitMem_reg PF13012.6 EAX79910.1 - 0.11 12.9 2.2 1.9 9.0 0.2 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function PRD PF00874.20 EAX79910.1 - 0.24 11.7 3.5 0.59 10.5 0.3 3.1 3 1 0 3 3 3 0 PRD domain KELK PF15796.5 EAX79910.1 - 0.3 11.6 2.2 4.9 7.7 0.2 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec63 PF02889.16 EAX79912.1 - 7.5e-11 41.7 0.0 8.4e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain DUF4108 PF13390.6 EAX79913.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX79913.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide RapH_N PF18801.1 EAX79914.1 - 0.38 10.9 2.7 1.5 8.9 1.3 2.1 1 1 1 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF4108 PF13390.6 EAX79915.1 - 5e-63 211.3 6.0 5.6e-63 211.2 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79916.1 - 1.5e-156 519.0 13.4 1.8e-156 518.7 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX79916.1 - 0.15 12.6 4.2 0.57 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX79916.1 - 0.15 11.9 0.8 0.51 10.2 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX79916.1 - 0.2 12.0 1.1 0.52 10.6 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Pox_D5 PF03288.16 EAX79917.1 - 8.8e-05 22.9 3.6 0.00056 20.3 3.6 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79917.1 - 0.04 14.5 0.2 0.083 13.5 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3839 PF12943.7 EAX79919.1 - 5.2e-116 386.3 5.5 6e-116 386.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX79919.1 - 0.053 13.0 0.5 0.079 12.5 0.3 1.4 1 1 0 1 1 1 0 Z1 domain Rx_N PF18052.1 EAX79919.1 - 1.3 9.3 5.1 4.3 7.7 0.1 3.0 2 1 1 3 3 3 0 Rx N-terminal domain Gly-zipper_Omp PF13488.6 EAX79921.1 - 0.0068 16.4 9.0 0.01 15.8 9.0 1.3 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX79921.1 - 0.29 9.4 0.0 0.33 9.3 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX79921.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX79921.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ResIII PF04851.15 EAX79922.1 - 6e-05 23.1 2.7 0.00012 22.2 2.7 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX79922.1 - 0.00037 20.3 0.0 0.0005 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX79922.1 - 0.00038 20.7 0.0 0.00066 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX79922.1 - 0.00071 19.4 0.9 0.0021 17.9 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX79922.1 - 0.0073 16.7 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX79922.1 - 0.033 13.9 0.2 0.28 10.9 0.0 2.1 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX79922.1 - 0.044 13.2 0.1 0.061 12.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX79922.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX79922.1 - 0.17 12.1 4.5 3.6 7.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX79923.1 - 0.045 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX79924.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79925.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX79926.1 - 3.3e-07 30.0 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79926.1 - 0.0045 16.7 0.1 0.006 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX79926.1 - 0.045 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX79926.1 - 0.063 13.0 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX79926.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX79926.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX79926.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) T5orf172 PF10544.9 EAX79927.1 - 4.7e-06 27.1 0.3 5.5e-05 23.7 0.2 2.3 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX79927.1 - 0.057 13.3 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 KilA-N domain DUF3148 PF11347.8 EAX79927.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) KilA-N PF04383.13 EAX79928.1 - 1.3e-13 50.8 0.1 2.7e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX79928.1 - 0.042 13.8 0.2 0.55 10.2 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX79929.1 - 1.2e-158 525.9 13.6 1.4e-158 525.6 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX79929.1 - 0.069 13.6 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX79929.1 - 0.12 12.9 7.0 1.9 9.0 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX79929.1 - 3.4 8.1 6.6 12 6.2 0.1 3.6 4 2 1 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX79930.1 - 9.9e-07 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF4795 PF16043.5 EAX79931.1 - 0.003 17.2 4.8 0.019 14.6 4.7 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX79931.1 - 1.2 9.4 4.6 11 6.5 0.2 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat FYVE_2 PF02318.16 EAX79933.1 - 0.043 14.0 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2897 PF11446.8 EAX79934.1 - 0.25 11.2 2.1 0.47 10.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX79935.1 - 1.2e-05 25.6 2.2 5.5e-05 23.6 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79935.1 - 0.034 14.8 0.1 0.073 13.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX79935.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX79935.1 - 0.092 12.7 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain CHASE3 PF05227.13 EAX79936.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX79936.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) DDE_1 PF03184.19 EAX79938.1 - 2.1e-13 50.3 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease T5orf172 PF10544.9 EAX79939.1 - 4.3e-07 30.4 0.1 1e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX79940.1 - 7.4e-61 204.3 7.6 8.3e-61 204.1 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX79942.1 - 2.7e-77 254.8 49.7 1.2e-32 111.7 12.7 6.2 4 2 2 6 6 6 3 Phage tail repeat like RFX_DNA_binding PF02257.15 EAX79943.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX79943.1 - 0.00063 20.2 1.7 0.00098 19.6 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX79943.1 - 0.038 14.0 0.9 0.073 13.1 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX79944.1 - 4.1e-156 517.6 13.3 4.9e-156 517.3 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX79944.1 - 0.11 12.0 0.1 0.83 9.1 0.0 2.1 1 1 1 2 2 2 0 SLOG cluster2 Glu-tRNAGln PF02686.15 EAX79944.1 - 0.25 11.7 2.6 0.75 10.1 1.1 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX79944.1 - 0.87 9.9 3.8 3.4 8.0 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KilA-N PF04383.13 EAX79945.1 - 1.3e-22 79.8 0.6 2.4e-22 78.9 0.6 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX79945.1 - 0.048 13.6 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF2939 PF11159.8 EAX79946.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX79946.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX79946.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX79946.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX79947.1 - 0.0061 16.6 0.2 0.0082 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PTR PF12789.7 EAX79948.1 - 1.1e-58 195.1 30.9 9.9e-34 115.2 13.6 4.7 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX79948.1 - 0.13 12.0 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PapD_N PF00345.20 EAX79949.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX79949.1 - 0.12 12.4 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4795 PF16043.5 EAX79951.1 - 3.3e-06 26.8 7.4 0.005 16.5 1.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) EpuA PF11772.8 EAX79951.1 - 0.044 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Phage_fiber PF03335.13 EAX79951.1 - 0.53 10.6 9.8 0.23 11.7 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat SEP PF08059.13 EAX79951.1 - 0.6 10.7 2.3 2.9 8.5 2.3 1.9 1 1 0 1 1 1 0 SEP domain PSP PF04046.16 EAX79953.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX79954.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX79956.1 - 2.6e-11 43.1 2.1 8.5e-11 41.4 2.1 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX79957.1 - 1.8e-146 486.0 10.6 2.3e-146 485.6 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX79957.1 - 0.01 16.3 0.5 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX79957.1 - 0.11 13.0 1.7 4.1 7.9 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX79957.1 - 0.52 10.6 2.7 3.8 7.9 0.0 3.2 2 2 2 4 4 4 0 Rx N-terminal domain Tup_N PF08581.10 EAX79957.1 - 0.79 10.1 4.9 9.4 6.6 0.2 3.2 2 2 2 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX79960.1 - 7.9e-07 29.6 0.2 2.2e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX79960.1 - 0.002 17.7 0.6 0.026 14.1 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX79960.1 - 0.022 14.6 1.7 0.072 13.0 0.4 2.4 2 2 0 2 2 2 0 KilA-N domain DUF2897 PF11446.8 EAX79961.1 - 0.43 10.5 2.3 0.79 9.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79962.1 - 4.7e-59 198.4 9.4 5.3e-59 198.3 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Flavodoxin_2 PF02525.17 EAX79964.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold MCRA PF06100.11 EAX79968.1 - 1.7e-63 215.2 0.0 1.9e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EAX79968.1 - 1e-07 32.1 0.1 6.1e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAS_N PF17828.1 EAX79974.1 - 0.0022 18.0 0.1 0.0032 17.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta CREPT PF16566.5 EAX79975.1 - 0.03 14.5 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX79975.1 - 1 9.5 5.7 0.33 11.1 1.6 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GGDEF PF00990.21 EAX79976.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX79976.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX79976.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79977.1 - 2.5e-58 196.1 7.7 2.7e-58 195.9 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX79978.1 - 1.3e-05 25.6 3.9 0.00019 21.9 3.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX79978.1 - 0.035 14.7 0.1 0.065 13.9 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX79978.1 - 0.064 13.2 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PTR PF12789.7 EAX79979.1 - 1.5e-48 162.7 29.2 1.6e-32 111.3 14.5 4.3 3 2 1 4 4 4 2 Phage tail repeat like DUF2897 PF11446.8 EAX79983.1 - 4 7.4 7.8 9.9 6.1 7.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79984.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX79985.1 - 2e-156 518.6 13.5 2.6e-156 518.2 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX79985.1 - 0.02 15.1 0.1 0.071 13.3 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF29 KELK PF15796.5 EAX79985.1 - 1.5 9.4 6.3 2.1 8.9 0.3 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4304 PF14137.6 EAX79986.1 - 0.028 14.6 0.1 0.028 14.6 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4304) DBP10CT PF08147.12 EAX79986.1 - 1.4 9.3 8.6 0.97 9.7 0.1 3.0 3 0 0 3 3 3 0 DBP10CT (NUC160) domain DNA_pol_B_2 PF03175.13 EAX79987.1 - 6.1e-25 88.0 4.8 9.1e-25 87.4 4.8 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Trypan_PARP PF05887.11 EAX79989.1 - 0.03 14.3 8.3 0.047 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX79989.1 - 3.7 8.0 5.1 5.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX79990.1 - 1.9e-79 266.6 9.7 2.4e-79 266.2 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF948 PF06103.11 EAX79991.1 - 0.61 10.4 7.7 0.7 10.2 7.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2121 PF09894.9 EAX79991.1 - 1.2 8.6 7.9 16 5.0 7.9 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) T5orf172 PF10544.9 EAX79992.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX79993.1 - 4e-25 87.8 0.0 5.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX79994.1 - 1.2e-07 31.5 1.2 1.4e-07 31.2 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX79994.1 - 0.0041 16.8 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX79994.1 - 0.0065 15.4 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF3783 PF12646.7 EAX79994.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX79994.1 - 0.076 12.7 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MSL1_dimer PF16801.5 EAX79994.1 - 0.13 12.0 1.5 0.27 11.0 1.5 1.6 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Peptidase_M49 PF03571.15 EAX79995.1 - 0.002 16.6 0.0 0.0027 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 DUF3839 PF12943.7 EAX79997.1 - 9e-38 130.1 1.1 1e-37 129.9 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX79997.1 - 0.066 13.6 0.1 0.077 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) DUF2897 PF11446.8 EAX79998.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX79999.1 - 1.1e-60 203.7 6.5 1.2e-60 203.6 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80000.1 - 6.4e-05 23.4 2.0 0.00035 21.0 2.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80000.1 - 0.053 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Amidase02_C PF12123.8 EAX80001.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX80002.1 - 3.7e-61 206.0 13.2 1.9e-59 200.4 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80002.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta ResIII PF04851.15 EAX80004.1 - 4.5e-05 23.5 2.0 8.7e-05 22.6 2.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80004.1 - 0.0003 20.6 0.0 0.00056 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX80004.1 - 0.00044 20.5 0.0 0.00077 19.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80004.1 - 0.0013 18.5 0.1 0.0022 17.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80004.1 - 0.0058 17.0 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80004.1 - 0.04 13.3 0.1 0.09 12.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX80004.1 - 0.063 12.9 0.4 0.096 12.3 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX80004.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX80004.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Polysacc_deac_2 PF04748.13 EAX80004.1 - 0.12 11.6 0.0 0.61 9.2 0.0 1.8 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase AAA_30 PF13604.6 EAX80004.1 - 0.24 11.1 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 EAX80006.1 - 8.6e-09 34.8 1.2 1.6e-08 33.9 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX80006.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX80006.1 - 0.15 12.1 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PadR PF03551.14 EAX80007.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RFX_DNA_binding PF02257.15 EAX80008.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX80008.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX80008.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pkinase PF00069.25 EAX80009.1 - 1.3e-15 57.5 0.0 1.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 EAX80009.1 - 3.8e-09 37.0 0.0 1.4e-08 35.2 0.0 1.9 2 1 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 EAX80009.1 - 0.00017 21.0 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_9 PF15410.6 EAX80009.1 - 0.00085 19.7 0.0 0.32 11.4 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain DUF2897 PF11446.8 EAX80012.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX80013.1 - 1.5e-49 167.6 5.9 1.6e-49 167.5 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX80015.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80015.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80015.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80015.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80015.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80015.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80015.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) CREPT PF16566.5 EAX80017.1 - 0.035 14.3 0.2 0.072 13.3 0.2 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX80017.1 - 0.97 9.6 5.9 0.34 11.1 1.6 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KilA-N PF04383.13 EAX80018.1 - 9.7e-46 154.2 0.1 1.7e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX80018.1 - 0.013 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DNA_pol_B_2 PF03175.13 EAX80019.1 - 4.7e-29 101.6 9.3 7.9e-29 100.8 9.3 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX80019.1 - 0.022 14.1 0.6 0.037 13.3 0.6 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX80019.1 - 0.033 14.2 3.1 0.99 9.5 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) PTR PF12789.7 EAX80020.1 - 1.3e-09 37.9 9.2 1.2e-08 34.8 5.2 4.9 4 1 0 4 4 4 2 Phage tail repeat like DUF1910 PF08928.10 EAX80020.1 - 0.0047 16.9 1.7 0.0058 16.6 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1910) ZZ PF00569.17 EAX80020.1 - 0.061 13.2 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type EMP24_GP25L PF01105.24 EAX80020.1 - 1.6 8.6 5.9 1.9 8.4 4.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Alpha-2-MRAP_C PF06401.11 EAX80020.1 - 6.1 6.7 10.5 1.9 8.4 5.6 2.3 2 1 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain GPS2_interact PF15784.5 EAX80021.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80021.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80022.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80022.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX80023.1 - 6.5e-08 32.3 1.1 7.7e-08 32.1 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80023.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80023.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80023.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX80024.1 - 1.2e-06 29.0 0.2 3.1e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80024.1 - 0.0016 18.3 0.1 0.011 15.6 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX80024.1 - 0.0057 16.2 0.4 0.06 12.9 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain PTR PF12789.7 EAX80027.1 - 1.2e-05 25.3 0.1 1.2e-05 25.3 0.1 4.5 5 1 0 5 5 5 1 Phage tail repeat like DUF445 PF04286.12 EAX80027.1 - 0.055 13.3 4.7 0.093 12.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX80027.1 - 0.094 12.5 0.1 0.37 10.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX80027.1 - 0.096 12.4 0.1 15 5.2 0.0 2.3 1 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX80027.1 - 0.61 10.6 0.0 0.61 10.6 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX80027.1 - 1.6 8.3 20.5 0.19 11.3 0.5 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX80027.1 - 8.3 6.9 12.6 18 5.8 0.7 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat HSP70 PF00012.20 EAX80028.1 - 0.93 7.6 7.8 1.1 7.3 7.8 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF3839 PF12943.7 EAX80030.1 - 1.1e-157 522.7 14.2 1.3e-157 522.5 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80030.1 - 0.092 13.2 6.1 0.7 10.4 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX80030.1 - 1.7 9.0 4.4 3.5 8.0 0.0 3.1 2 2 2 4 4 4 0 Rx N-terminal domain DUF3839 PF12943.7 EAX80031.1 - 1.2e-86 290.1 5.2 1.4e-86 289.9 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80032.1 - 5e-86 288.1 6.9 5.7e-86 287.9 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX80033.1 - 9.5e-11 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX80034.1 - 0.00018 22.0 0.0 0.00043 20.8 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80034.1 - 0.0061 16.4 1.1 0.024 14.5 0.5 2.3 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80035.1 - 1.2e-72 244.3 6.3 1.6e-72 243.9 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX80036.1 - 7.4e-12 45.2 18.3 2.4e-08 33.9 0.4 5.5 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX80036.1 - 4 7.0 17.8 0.13 11.8 1.9 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX80036.1 - 6.7 7.2 27.6 5.5 7.4 0.3 5.5 5 0 0 5 5 5 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX80037.1 - 2.3e-81 272.9 10.8 2.9e-81 272.5 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80037.1 - 0.087 13.4 0.2 0.15 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX80037.1 - 0.15 11.9 1.2 0.45 10.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX80039.1 - 3.3e-38 130.0 0.4 8.7e-38 128.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80039.1 - 0.019 15.2 0.3 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) TALPID3 PF15324.6 EAX80040.1 - 2.6 5.6 10.1 3.4 5.2 10.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Amidase02_C PF12123.8 EAX80041.1 - 0.0075 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX80042.1 - 6.9e-278 921.6 21.3 6.9e-278 921.6 21.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80042.1 - 0.024 14.9 0.2 1.1 9.6 0.2 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated FAS_N PF17828.1 EAX80043.1 - 0.022 14.8 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX80044.1 - 1.5e-125 417.5 7.1 1.7e-125 417.4 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80044.1 - 0.053 13.0 1.2 0.078 12.5 0.6 1.6 1 1 1 2 2 2 0 Z1 domain KELK PF15796.5 EAX80044.1 - 0.13 12.7 2.0 0.99 9.9 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX80044.1 - 0.15 12.7 1.0 0.58 10.8 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX80046.1 - 4.8e-38 129.5 0.5 1.1e-37 128.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80046.1 - 0.0057 17.2 0.2 0.018 15.7 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family KilA-N PF04383.13 EAX80047.1 - 2.5e-14 53.0 0.0 4.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX80048.1 - 6.1e-59 199.4 3.3 6.8e-59 199.2 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80048.1 - 0.042 14.3 1.8 0.11 13.0 1.8 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX80048.1 - 0.12 13.1 1.4 1.1 9.9 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX80049.1 - 1.5e-11 44.2 0.6 2.3e-11 43.5 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain TPR_MLP1_2 PF07926.12 EAX80050.1 - 0.012 15.7 0.4 0.015 15.4 0.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX80050.1 - 0.052 13.4 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX80050.1 - 0.082 12.8 2.2 0.082 12.8 2.2 2.4 3 0 0 3 3 3 0 Spo12 family Tho2 PF11262.8 EAX80050.1 - 0.12 11.5 3.3 0.14 11.4 3.3 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KilA-N PF04383.13 EAX80051.1 - 3.9e-17 62.1 0.0 6.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX80051.1 - 0.21 11.0 0.3 0.43 10.0 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain KilA-N PF04383.13 EAX80052.1 - 4.8e-25 87.6 1.7 5e-25 87.5 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX80052.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX80053.1 - 7.1e-08 32.2 1.1 8.6e-08 31.9 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80053.1 - 0.0041 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80053.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80053.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF257 PF03192.13 EAX80054.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX80054.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Flavodoxin_2 PF02525.17 EAX80056.1 - 1.4e-05 24.9 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3839 PF12943.7 EAX80057.1 - 2.3e-156 518.4 13.1 2.9e-156 518.1 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80057.1 - 0.12 12.7 0.3 2.5 8.4 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX80057.1 - 0.82 10.2 4.9 8.6 6.9 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX80058.1 - 2.8e-08 33.5 0.7 3.2e-08 33.4 0.7 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80058.1 - 0.0036 17.0 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80058.1 - 0.071 12.8 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80058.1 - 0.078 12.9 0.4 0.64 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX80059.1 - 4e-155 514.3 12.2 4.9e-155 514.0 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80059.1 - 0.056 13.9 1.9 2.1 8.9 0.0 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX80059.1 - 0.35 11.2 3.2 1 9.7 0.1 2.9 3 0 0 3 3 3 0 PRD domain DUF2408 PF10303.9 EAX80059.1 - 0.53 10.9 4.3 0.25 11.9 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MULE PF10551.9 EAX80060.1 - 2.1e-08 34.4 2.5 3.6e-08 33.7 0.1 2.6 3 0 0 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX80060.1 - 0.0039 16.9 0.3 0.019 14.7 0.2 2.1 1 1 0 1 1 1 1 Transposase WRKY PF03106.15 EAX80060.1 - 0.037 14.3 2.2 0.075 13.3 0.6 2.4 1 1 1 2 2 2 0 WRKY DNA -binding domain Transposase_mut PF00872.18 EAX80060.1 - 1.2 7.9 6.2 0.33 9.7 2.0 2.1 2 1 0 2 2 2 0 Transposase, Mutator family DUF4108 PF13390.6 EAX80063.1 - 7.1e-54 181.6 8.0 7.9e-54 181.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX80066.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX80068.1 - 0.058 13.5 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX80068.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX80068.1 - 6.2 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family BACK PF07707.15 EAX80069.1 - 0.048 13.8 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch SH3_9 PF14604.6 EAX80069.1 - 0.056 13.3 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 Variant SH3 domain PTR PF12789.7 EAX80073.1 - 1e-51 172.8 25.6 1.3e-30 105.3 10.7 5.6 7 1 0 7 7 7 2 Phage tail repeat like DUF4116 PF13475.6 EAX80073.1 - 0.017 14.9 0.4 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX80073.1 - 1 8.9 23.1 0.95 9.0 12.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Trypan_PARP PF05887.11 EAX80074.1 - 0.018 15.0 8.3 0.022 14.7 8.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80074.1 - 2.2 8.7 6.2 2.6 8.5 6.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX80076.1 - 4.3e-21 75.8 1.4 7.3e-20 71.8 1.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX80077.1 - 0.096 12.5 1.5 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain MORN_2 PF07661.13 EAX80078.1 - 0.01 15.9 0.0 68 4.2 0.0 4.7 6 0 0 6 6 6 0 MORN repeat variant DUF2689 PF10894.8 EAX80078.1 - 0.014 15.1 1.5 13 5.7 0.1 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF2689) T5orf172 PF10544.9 EAX80079.1 - 0.0056 17.2 0.2 0.012 16.2 0.2 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80079.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX80079.1 - 0.1 12.1 0.5 0.21 11.1 0.2 1.6 2 0 0 2 2 2 0 Legume lectin domain T5orf172 PF10544.9 EAX80080.1 - 3.7e-06 27.4 0.2 8.8e-06 26.2 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80080.1 - 0.1 12.5 1.0 0.24 11.2 0.5 2.0 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX80081.1 - 1.3e-31 108.7 0.7 2.7e-31 107.7 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX80082.1 - 6.7e-07 29.0 2.7 6.7e-07 29.0 2.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80082.1 - 3.7e-05 24.0 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80082.1 - 6.9e-05 22.7 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80082.1 - 0.0002 21.4 3.4 0.00049 20.1 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80082.1 - 0.00044 20.1 0.0 0.00082 19.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80082.1 - 0.001 18.9 0.7 0.0018 18.1 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80082.1 - 0.0017 18.0 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80082.1 - 0.0097 16.2 0.0 0.02 15.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX80082.1 - 0.061 12.9 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80082.1 - 0.089 12.2 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX80082.1 - 0.092 13.2 0.1 0.78 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX80082.1 - 0.18 12.2 3.6 3.3 8.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX80082.1 - 0.32 11.3 3.8 7.8 6.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX80084.1 - 2.3e-54 183.2 6.0 2.5e-54 183.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VASP_tetra PF08776.11 EAX80085.1 - 0.051 13.1 0.5 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain PapD_N PF00345.20 EAX80087.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain KilA-N PF04383.13 EAX80088.1 - 3.6e-17 62.2 0.2 6.6e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain PRD PF00874.20 EAX80088.1 - 0.046 14.0 3.0 6 7.2 0.1 2.8 2 1 0 2 2 2 0 PRD domain PapD_N PF00345.20 EAX80089.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX80089.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX80090.1 - 9.5e-09 34.6 0.9 1.9e-08 33.7 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX80090.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX80090.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Ank PF00023.30 EAX80091.1 - 1.4e-60 199.3 2.7 1.8e-09 37.6 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 EAX80091.1 - 5.5e-54 179.5 6.6 3.3e-12 46.4 0.0 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX80091.1 - 4e-47 158.0 7.3 2e-09 37.8 0.0 7.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX80091.1 - 1.4e-45 153.8 9.1 1.2e-15 57.9 0.4 5.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX80091.1 - 1.2e-40 132.8 9.6 2.2e-06 27.6 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat DUF3447 PF11929.8 EAX80091.1 - 3e-25 88.0 7.4 3e-25 88.0 7.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) ThiS-like PF14453.6 EAX80091.1 - 2e-07 30.9 2.8 2.7 8.1 0.1 5.4 1 1 4 5 5 5 2 ThiS-like ubiquitin GATase_7 PF13537.6 EAX80091.1 - 0.00077 19.4 0.0 39 4.2 0.0 4.8 4 1 2 6 6 6 0 Glutamine amidotransferase domain MetallophosN PF16371.5 EAX80091.1 - 0.0012 19.1 0.0 1.8 8.9 0.0 3.6 1 1 2 4 4 4 2 N terminal of Calcineurin-like phosphoesterase NMT1_2 PF13379.6 EAX80091.1 - 0.0014 18.4 0.0 3.8 7.1 0.0 3.1 1 1 2 3 3 3 2 NMT1-like family Clathrin PF00637.20 EAX80091.1 - 0.0026 17.6 1.7 1.5 8.7 0.0 3.8 2 1 1 4 4 4 1 Region in Clathrin and VPS PH_8 PF15409.6 EAX80091.1 - 0.0097 16.2 0.4 66 3.9 0.0 4.3 1 1 2 4 4 4 0 Pleckstrin homology domain CEP44 PF15007.6 EAX80091.1 - 0.025 14.8 0.0 13 6.0 0.0 3.9 2 1 4 6 6 6 0 Centrosomal spindle body, CEP44 Staphylokinase PF02821.16 EAX80091.1 - 0.027 14.9 0.5 75 3.8 0.0 4.1 1 1 3 4 4 4 0 Staphylokinase/Streptokinase family CCDC84 PF14968.6 EAX80091.1 - 0.061 12.9 0.0 29 4.1 0.0 3.1 1 1 2 3 3 3 0 Coiled coil protein 84 Pox_D5 PF03288.16 EAX80092.1 - 3.2e-05 24.3 3.2 0.00021 21.7 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80092.1 - 0.051 14.2 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX80092.1 - 0.094 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX80093.1 - 5.7e-59 198.1 7.8 6.3e-59 198.0 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX80095.1 - 2.2e-05 24.5 0.2 3.1e-05 24.1 0.2 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80095.1 - 0.00034 20.4 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80095.1 - 0.0016 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX80095.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80095.1 - 0.0053 17.1 0.0 0.0075 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80095.1 - 0.027 13.9 0.0 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX80095.1 - 0.057 13.1 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX80095.1 - 0.069 12.7 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX80095.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4107 PF13389.6 EAX80096.1 - 5.7e-35 120.9 3.4 6.9e-35 120.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX80096.1 - 0.028 12.9 0.9 0.027 12.9 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase Collagen_bind_2 PF12904.7 EAX80097.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Pkinase PF00069.25 EAX80100.1 - 9e-58 195.7 0.1 1.3e-57 195.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX80100.1 - 1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX80100.1 - 3.3e-08 33.2 0.0 4.6e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EAX80100.1 - 5.6e-06 26.5 0.3 2.3e-05 24.4 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX80100.1 - 3.3e-05 23.6 0.2 5e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAX80100.1 - 9.4e-05 21.8 0.7 0.00016 21.1 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX80100.1 - 0.006 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YukC PF10140.9 EAX80100.1 - 0.006 15.5 0.1 0.0087 14.9 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 EAX80100.1 - 0.059 13.0 0.7 0.12 11.9 0.7 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF3839 PF12943.7 EAX80102.1 - 8.9e-81 270.9 3.4 1e-80 270.7 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80102.1 - 0.025 14.1 0.2 0.028 13.9 0.2 1.1 1 0 0 1 1 1 0 Z1 domain T5orf172 PF10544.9 EAX80103.1 - 1.1e-06 29.1 0.1 2.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX80104.1 - 5.5e-100 333.8 8.1 6.2e-100 333.6 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX80104.1 - 0.1 13.5 0.7 3.6 8.6 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Glu-tRNAGln PF02686.15 EAX80104.1 - 0.18 12.1 1.0 0.42 10.9 1.0 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3781 PF12636.7 EAX80105.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX80106.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80106.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Collagen_bind_2 PF12904.7 EAX80107.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4456 PF14644.6 EAX80109.1 - 4.3e-27 95.2 1.3 4.3e-27 95.2 1.3 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) DUF2897 PF11446.8 EAX80110.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX80111.1 - 2.5e-05 24.7 2.5 0.00016 22.1 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80111.1 - 0.09 13.4 0.2 0.18 12.4 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PTR PF12789.7 EAX80112.1 - 6.8e-28 96.5 12.1 6.8e-28 96.5 12.1 2.4 2 0 0 2 2 2 1 Phage tail repeat like Phage_fiber PF03335.13 EAX80112.1 - 6.5 7.2 28.9 3.4 8.1 1.1 5.6 5 0 0 5 5 5 0 Phage tail fibre repeat MULE PF10551.9 EAX80113.1 - 1.5e-05 25.3 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FliJ PF02050.16 EAX80114.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX80115.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80116.1 - 2.3e-39 135.3 4.4 3.2e-39 134.8 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX80116.1 - 0.078 13.3 0.7 0.26 11.6 0.1 2.0 1 1 1 2 2 2 0 PRD domain C2 PF00168.30 EAX80117.1 - 1.5e-70 234.0 8.9 3.2e-22 78.8 0.2 4.2 4 0 0 4 4 4 4 C2 domain DOCK-C2 PF14429.6 EAX80117.1 - 7.1e-06 26.0 3.1 0.45 10.3 0.1 4.2 3 1 1 4 4 4 2 C2 domain in Dock180 and Zizimin proteins B9-C2 PF07162.11 EAX80117.1 - 7.1e-06 26.3 0.0 1 9.6 0.0 3.6 3 1 0 3 3 3 3 Ciliary basal body-associated, B9 protein FAS_meander PF17951.1 EAX80117.1 - 0.097 12.5 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain DUF4107 PF13389.6 EAX80118.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80118.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX80119.1 - 1.2e-41 141.1 0.7 2.2e-41 140.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80119.1 - 0.0032 18.1 0.1 0.0095 16.6 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX80120.1 - 6e-39 133.9 4.5 8.3e-39 133.5 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX80120.1 - 0.046 12.9 0.1 0.057 12.6 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Pox_A32 PF04665.12 EAX80121.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80121.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80121.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80121.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80121.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80121.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80121.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80121.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX80121.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80121.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80121.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80121.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX80122.1 - 1.7e-65 220.1 9.6 4.9e-65 218.6 9.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80125.1 - 9.9e-153 506.5 11.9 1.2e-152 506.3 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80125.1 - 0.096 12.5 0.4 0.28 11.0 0.4 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX80125.1 - 0.39 11.2 3.6 3.7 8.1 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80126.1 - 5.5e-152 504.1 12.3 7e-152 503.7 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX80126.1 - 0.035 14.4 0.6 10 6.5 0.1 3.4 3 0 0 3 3 3 0 Tup N-terminal FKBP_N PF01346.18 EAX80126.1 - 0.14 13.1 0.8 0.37 11.8 0.2 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2408 PF10303.9 EAX80126.1 - 5.3 7.6 6.6 1.1 9.8 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80126.1 - 6.1 7.4 8.0 1.7 9.1 0.4 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX80127.1 - 0.052 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX80127.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX80128.1 - 3.1e-09 36.2 1.0 6.1e-09 35.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX80128.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor YqeY PF09424.10 EAX80129.1 - 0.074 13.1 0.6 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 Yqey-like protein DUF3781 PF12636.7 EAX80130.1 - 0.027 14.3 1.0 0.047 13.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_A32 PF04665.12 EAX80131.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein ANAPC4_WD40 PF12894.7 EAX80132.1 - 3.7e-08 33.6 0.0 0.0016 18.7 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EAX80132.1 - 7.1e-07 28.8 0.8 0.009 15.4 0.1 2.7 2 1 2 4 4 4 2 CPSF A subunit region WD40_like PF17005.5 EAX80132.1 - 0.00017 21.0 8.2 0.037 13.4 0.6 2.3 1 1 0 1 1 1 1 WD40-like domain pXO2-34 PF17362.2 EAX80132.1 - 0.0097 15.8 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function IKI3 PF04762.12 EAX80132.1 - 0.01 13.9 0.1 0.24 9.4 0.1 2.0 1 1 1 2 2 2 0 IKI3 family WD40 PF00400.32 EAX80132.1 - 0.011 16.6 5.6 24 6.0 0.0 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EAX80132.1 - 0.014 13.9 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EAX80132.1 - 0.015 14.3 0.1 0.025 13.6 0.1 1.4 1 1 0 1 1 1 0 Coatomer WD associated region DUF3839 PF12943.7 EAX80134.1 - 6.4e-158 523.5 13.0 8.1e-158 523.2 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX80134.1 - 0.029 14.6 0.9 0.062 13.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX80134.1 - 0.16 12.4 5.4 1.9 9.0 0.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80134.1 - 1.6 9.3 6.6 0.39 11.3 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glyco_transf_64 PF09258.10 EAX80136.1 - 1.1e-33 116.5 0.3 1.4e-33 116.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF3839 PF12943.7 EAX80137.1 - 2.5e-25 89.3 4.3 3.8e-25 88.8 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX80137.1 - 0.092 11.9 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II RecO_C PF02565.15 EAX80137.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal PG_binding_2 PF08823.11 EAX80139.1 - 0.0088 16.3 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Pox_A32 PF04665.12 EAX80140.1 - 4.9e-07 29.5 2.7 4.9e-07 29.5 2.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80140.1 - 3.8e-05 24.0 0.2 0.00028 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80140.1 - 3.8e-05 23.5 0.3 0.38 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80140.1 - 0.00034 20.7 4.2 0.00057 19.9 3.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80140.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80140.1 - 0.0012 18.7 0.6 0.0023 17.8 0.4 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80140.1 - 0.0036 17.0 2.7 0.012 15.3 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80140.1 - 0.013 15.8 0.0 0.032 14.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain TPK_catalytic PF04263.16 EAX80140.1 - 0.084 12.9 0.7 1.3 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX80140.1 - 0.089 12.4 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80140.1 - 0.1 13.0 0.1 0.89 10.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80140.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80140.1 - 0.44 10.8 4.0 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX80140.1 - 0.63 10.7 11.4 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX80141.1 - 2e-25 89.7 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80142.1 - 2.6e-148 492.1 15.9 3.1e-148 491.8 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80142.1 - 0.094 12.6 0.8 0.28 11.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80142.1 - 2.4 8.5 4.7 4.1 7.8 0.0 3.2 2 2 1 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX80142.1 - 2.5 8.6 8.5 2.6 8.6 1.1 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf-C2H2_assoc2 PF16624.5 EAX80145.1 - 3 8.9 10.2 0.21 12.6 3.3 2.3 2 1 0 2 2 2 0 Unstructured region upstream of a zinc-finger DUF3839 PF12943.7 EAX80146.1 - 6.2e-119 395.8 12.8 7.8e-119 395.5 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80146.1 - 0.14 12.0 1.5 0.44 10.4 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80146.1 - 0.26 11.8 3.4 1.8 9.0 0.0 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX80147.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80147.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80147.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80147.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX80148.1 - 1e-71 241.3 6.4 1.3e-71 240.9 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX80149.1 - 1.2e-34 118.5 1.1 1.9e-34 117.9 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80149.1 - 0.00097 19.3 0.1 0.0027 17.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX80149.1 - 0.0064 16.9 5.0 0.2 12.2 1.1 2.4 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 DBR1 PF05011.13 EAX80149.1 - 1 9.8 4.5 0.55 10.7 0.9 2.0 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Pox_A32 PF04665.12 EAX80150.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80150.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80150.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80150.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80150.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80150.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80150.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX80151.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX80151.1 - 0.064 13.4 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF2408 PF10303.9 EAX80151.1 - 0.088 13.4 0.5 0.1 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX80151.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 PTR PF12789.7 EAX80152.1 - 1.4e-25 89.1 14.5 1.4e-25 89.1 14.5 4.6 4 1 0 5 5 5 1 Phage tail repeat like SAS4 PF15460.6 EAX80152.1 - 0.039 14.0 2.4 6.9 6.8 0.3 3.0 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF4116 PF13475.6 EAX80152.1 - 0.12 12.1 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3464 PF11947.8 EAX80153.1 - 2 8.2 4.5 1.7 8.4 3.4 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX80154.1 - 5.1e-57 191.8 6.9 5.6e-57 191.7 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2866 PF11065.8 EAX80155.1 - 0.0092 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2866) DUF4106 PF13388.6 EAX80159.1 - 7.6e-65 219.8 4.0 1.3e-64 219.0 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KilA-N PF04383.13 EAX80160.1 - 1.1e-31 109.0 0.5 2.6e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80161.1 - 2.8e-115 383.9 6.3 3.3e-115 383.7 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80161.1 - 0.26 11.8 1.5 0.97 9.9 0.5 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX80161.1 - 3.6 7.9 5.3 10 6.5 0.1 2.9 2 1 1 3 3 3 0 Rx N-terminal domain Tho2 PF11262.8 EAX80162.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KilA-N PF04383.13 EAX80163.1 - 1.2e-23 83.1 0.7 2.4e-23 82.1 0.0 1.8 2 1 1 3 3 3 1 KilA-N domain DUF3839 PF12943.7 EAX80164.1 - 3e-79 265.9 8.8 3.8e-79 265.6 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GPS2_interact PF15784.5 EAX80166.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80166.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX80168.1 - 3e-31 108.8 16.1 4.2e-31 108.3 16.1 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX80169.1 - 4.6e-158 524.0 11.4 5.8e-158 523.6 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX80169.1 - 0.12 12.8 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX80169.1 - 0.98 9.9 5.3 4.8 7.7 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80170.1 - 8.4e-156 516.6 12.3 1e-155 516.3 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80170.1 - 0.07 13.6 4.5 2.1 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Lectin_legB PF00139.19 EAX80171.1 - 0.0025 17.4 0.3 0.37 10.3 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX80171.1 - 0.0051 17.3 0.1 0.013 16.1 0.1 1.7 2 0 0 2 2 2 1 T5orf172 domain Gly_rich PF12810.7 EAX80172.1 - 4.3e-32 112.0 18.2 7e-32 111.3 18.2 1.3 1 1 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX80173.1 - 1.7e-157 522.1 13.2 2.1e-157 521.8 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80173.1 - 0.029 14.9 1.5 0.12 12.8 0.2 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX80173.1 - 0.17 11.8 1.5 0.41 10.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX80173.1 - 0.27 11.8 5.3 0.17 12.5 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80173.1 - 0.36 11.3 5.2 5 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX80175.1 - 5.7e-63 211.1 5.7 6.4e-63 211.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX80176.1 - 0.12 12.3 1.9 0.25 11.2 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX80177.1 - 1.5e-41 140.7 0.5 3.7e-41 139.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80177.1 - 0.012 16.3 0.1 0.038 14.6 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX80177.1 - 0.24 11.4 2.7 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein ANAPC15 PF15243.6 EAX80177.1 - 1.9 9.0 6.6 0.97 9.9 2.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 ResIII PF04851.15 EAX80178.1 - 2.2e-05 24.5 0.3 2.9e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80178.1 - 0.00027 20.7 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX80178.1 - 0.00047 20.5 0.0 0.00071 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80178.1 - 0.0019 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80178.1 - 0.0066 16.8 0.0 0.0091 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80178.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX80178.1 - 0.086 12.4 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX80178.1 - 0.096 12.4 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein NIBRIN_BRCT_II PF16508.5 EAX80178.1 - 0.099 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_30 PF13604.6 EAX80178.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain ARGLU PF15346.6 EAX80179.1 - 0.0012 18.7 8.5 0.0017 18.3 8.5 1.1 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 KilA-N PF04383.13 EAX80180.1 - 5.7e-44 148.5 0.6 1.2e-43 147.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80180.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF2939 PF11159.8 EAX80181.1 - 0.0059 17.0 0.4 0.0068 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX80181.1 - 1 9.4 3.6 1.1 9.3 3.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX80182.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta VirE PF05272.11 EAX80184.1 - 1.1e-05 25.3 0.1 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX80184.1 - 0.014 14.5 1.7 0.037 13.1 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX80184.1 - 0.085 13.3 0.1 0.2 12.1 0.1 1.8 1 1 0 1 1 1 0 RNA helicase DUF4108 PF13390.6 EAX80185.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX80185.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX80186.1 - 0.74 9.7 3.9 0.98 9.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX80187.1 - 3.8e-30 104.0 0.4 9e-30 102.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Aa_trans PF01490.18 EAX80189.1 - 6.1e-11 41.7 16.6 7.3e-11 41.4 16.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PSI_8 PF00796.18 EAX80189.1 - 0.033 14.0 4.6 0.033 14.0 4.6 2.7 4 0 0 4 4 4 0 Photosystem I reaction centre subunit VIII DUF3522 PF12036.8 EAX80189.1 - 0.97 9.7 10.2 6.2 7.1 10.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Myb_DNA-binding PF00249.31 EAX80191.1 - 6.5e-26 90.3 0.0 2.6e-13 49.9 0.0 2.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX80191.1 - 4e-21 75.0 0.1 8.6e-15 54.7 0.1 2.9 1 1 2 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX80191.1 - 0.024 14.7 0.0 1.7 8.7 0.0 2.5 1 1 1 2 2 2 0 SLIDE GPS2_interact PF15784.5 EAX80192.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80192.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 EAX80194.1 - 5.4e-45 151.9 28.0 1.6e-21 76.6 2.7 5.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX80194.1 - 2.6e-43 144.6 15.9 1.5e-08 34.7 0.1 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX80194.1 - 2.7e-41 139.4 11.3 6.3e-13 49.0 0.2 6.0 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX80194.1 - 1.8e-37 123.1 16.5 8.4e-07 28.8 0.0 8.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX80194.1 - 1.7e-26 91.9 9.8 9.9e-08 32.1 0.3 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX80194.1 - 2.2e-18 66.0 10.7 2.2e-18 66.0 10.7 4.1 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) PTS_EIIA_1 PF00358.20 EAX80194.1 - 0.053 13.3 0.1 2.2 8.1 0.0 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF3839 PF12943.7 EAX80195.1 - 3.7e-58 196.8 3.6 4.8e-58 196.5 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80195.1 - 0.063 12.8 0.1 0.068 12.7 0.1 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX80195.1 - 0.21 12.2 1.2 2.1 9.0 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX80196.1 - 6.6e-80 268.1 11.7 8.7e-80 267.7 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX80196.1 - 0.067 12.7 0.4 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX80197.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80197.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80197.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80197.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80197.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80197.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80197.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Meiosis_expr PF15163.6 EAX80199.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX80199.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX80199.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family EpuA PF11772.8 EAX80200.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta DNA_pol_B_2 PF03175.13 EAX80202.1 - 1.8e-21 76.6 4.5 2.7e-21 76.0 4.5 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX80203.1 - 5.9e-11 41.9 7.8 8.4e-11 41.4 4.4 2.0 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX80203.1 - 0.11 12.1 1.0 0.18 11.3 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family Trypan_PARP PF05887.11 EAX80204.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80204.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX80205.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX80205.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX80206.1 - 1.3e-41 140.9 0.4 1.3e-41 140.9 0.4 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80206.1 - 0.0095 16.5 0.2 0.041 14.5 0.0 2.1 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX80207.1 - 3.7e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80207.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80207.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80207.1 - 0.061 13.1 0.1 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80207.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80207.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX80208.1 - 3.4e-07 30.0 0.1 5.3e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX80210.1 - 4e-33 113.6 0.5 9.5e-33 112.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80210.1 - 0.022 15.4 0.0 0.061 14.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX80211.1 - 7.2e-07 28.9 2.3 7.2e-07 28.9 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX80211.1 - 4.1e-05 23.4 0.3 0.38 10.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX80211.1 - 5.3e-05 23.5 0.2 0.00038 20.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80211.1 - 0.00017 21.6 4.3 0.00037 20.6 4.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80211.1 - 0.00094 19.0 0.1 0.0017 18.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80211.1 - 0.0034 17.2 1.2 0.0062 16.4 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80211.1 - 0.0075 16.6 0.0 0.017 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80211.1 - 0.0079 15.9 2.3 0.015 14.9 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA PF00004.29 EAX80211.1 - 0.035 14.5 0.1 0.31 11.5 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX80211.1 - 0.092 12.8 0.6 1.4 9.0 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX80211.1 - 0.19 11.3 0.0 0.85 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX80211.1 - 0.61 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX80211.1 - 0.68 10.6 11.6 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 NOG1_N PF17835.1 EAX80212.1 - 0.0017 18.4 2.7 0.0049 16.9 2.6 1.7 1 1 0 1 1 1 1 NOG1 N-terminal helical domain LRRFIP PF09738.9 EAX80212.1 - 0.26 10.7 8.0 0.29 10.6 8.0 1.0 1 0 0 1 1 1 0 LRRFIP family zf-C2H2_aberr PF17017.5 EAX80212.1 - 0.4 10.8 4.1 0.7 10.0 4.1 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger Phage_Gp23 PF10669.9 EAX80212.1 - 2.5 8.5 10.5 0.49 10.7 4.8 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Myb_DNA-binding PF00249.31 EAX80213.1 - 4.9e-38 129.1 13.6 4.4e-16 58.8 1.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX80213.1 - 5.4e-33 113.0 10.6 6.1e-13 48.8 0.3 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EAX80213.1 - 1.9e-05 24.6 0.7 0.24 11.5 0.0 3.4 2 2 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 EAX80213.1 - 5.9e-05 22.9 3.6 0.00032 20.5 0.0 2.7 2 1 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EAX80213.1 - 0.00051 20.1 3.6 2.5 8.3 0.1 3.3 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX80213.1 - 0.015 15.5 3.8 6.5 7.0 0.0 3.9 2 2 1 3 3 3 0 Rap1 Myb domain T5orf172 PF10544.9 EAX80214.1 - 1.4e-06 28.7 0.2 3.4e-06 27.5 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80214.1 - 0.047 13.2 0.7 0.51 9.8 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX80214.1 - 0.11 12.4 2.6 0.36 10.7 0.8 2.5 2 2 0 2 2 2 0 KilA-N domain DUF2939 PF11159.8 EAX80215.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX80215.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX80216.1 - 0.065 13.2 0.2 0.09 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX80217.1 - 1.2e-155 516.1 13.8 1.3e-155 515.9 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80217.1 - 0.49 10.9 8.7 1.7 9.2 0.9 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phage_TTP_1 PF04630.12 EAX80218.1 - 0.08 12.2 0.0 0.092 12.1 0.0 1.0 1 0 0 1 1 1 0 Phage tail tube protein BspA_v PF18220.1 EAX80220.1 - 0.28 11.3 5.2 2 8.5 0.9 2.1 2 0 0 2 2 2 0 Adhesin BspA variable domain I-set PF07679.16 EAX80221.1 - 0.001 19.1 1.2 0.0042 17.1 0.1 2.5 3 1 0 3 3 3 1 Immunoglobulin I-set domain PBP PF01161.20 EAX80221.1 - 0.01 16.2 0.1 3.8 7.8 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylethanolamine-binding protein Pox_Ag35 PF03286.14 EAX80222.1 - 1.8 8.3 6.6 3 7.6 6.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GGDEF PF00990.21 EAX80223.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX80224.1 - 5.8e-64 214.3 6.4 6.4e-64 214.2 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80225.1 - 4.6e-05 23.8 2.1 0.00022 21.7 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like GPS2_interact PF15784.5 EAX80226.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80226.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX80228.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80228.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80228.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80228.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80228.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80228.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80228.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX80229.1 - 1.7e-19 69.7 1.5 2.4e-19 69.2 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80229.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family GAGA_bind PF06217.12 EAX80231.1 - 0.048 13.9 4.2 0.058 13.7 4.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4108 PF13390.6 EAX80232.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80233.1 - 1.3e-05 25.6 2.6 7e-05 23.2 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80233.1 - 0.036 14.7 0.1 0.071 13.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX80233.1 - 0.083 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF846 PF05832.12 EAX80234.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) TFCD_C PF12612.8 EAX80235.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal TPR_MLP1_2 PF07926.12 EAX80237.1 - 0.004 17.2 1.2 0.005 16.9 1.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein KilA-N PF04383.13 EAX80238.1 - 7.1e-23 80.6 0.3 1.3e-22 79.7 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX80238.1 - 0.046 13.7 0.5 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4108 PF13390.6 EAX80239.1 - 6.9e-79 262.7 11.9 7.9e-79 262.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TPR_MLP1_2 PF07926.12 EAX80240.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX80240.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX80240.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family TMP PF05017.14 EAX80241.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat SL4P PF17618.2 EAX80242.1 - 0.099 12.7 0.6 0.21 11.6 0.5 1.7 1 1 0 1 1 1 0 Uncharacterized Strongylid L4 protein Trypan_PARP PF05887.11 EAX80244.1 - 0.02 14.9 9.9 0.028 14.4 9.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX80246.1 - 1.8e-21 75.9 20.8 1.3e-16 60.4 1.9 4.8 6 0 0 6 6 6 2 Phage tail repeat like DUF3839 PF12943.7 EAX80247.1 - 1.2e-103 345.8 9.5 1.4e-103 345.5 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80247.1 - 0.37 11.3 3.4 3.5 8.1 0.0 2.6 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Parathyroid PF01279.17 EAX80249.1 - 0.052 14.2 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Trypan_PARP PF05887.11 EAX80250.1 - 0.022 14.7 8.3 0.028 14.4 8.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80250.1 - 1.6 9.2 5.6 2 8.9 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX80251.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80251.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PadR PF03551.14 EAX80253.1 - 0.081 12.9 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family T5orf172 PF10544.9 EAX80254.1 - 7.6e-07 29.6 0.5 2.2e-06 28.1 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX80254.1 - 0.004 16.7 0.5 0.048 13.2 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain NDUFB10 PF10249.9 EAX80255.1 - 0.034 14.6 0.7 7.7 7.0 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 T5orf172 PF10544.9 EAX80256.1 - 1.6e-06 28.6 0.2 3.1e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF5104 PF17117.5 EAX80257.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF5104) DUF4107 PF13389.6 EAX80258.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX80259.1 - 2e-62 209.3 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX80259.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3464 PF11947.8 EAX80260.1 - 1.6 8.5 4.2 2.9 7.6 4.2 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pox_A32 PF04665.12 EAX80261.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX80261.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase ResIII PF04851.15 EAX80262.1 - 1.9e-05 24.7 0.6 3e-05 24.1 0.6 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80262.1 - 0.00028 20.7 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX80262.1 - 0.00045 20.5 0.0 0.00067 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80262.1 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80262.1 - 0.0067 16.8 0.0 0.0091 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80262.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX80262.1 - 0.075 12.8 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein SWI2_SNF2 PF18766.1 EAX80262.1 - 0.085 12.5 0.2 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX80262.1 - 0.091 12.3 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX80262.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX80262.1 - 0.23 11.0 1.8 0.16 11.5 0.4 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase PTR PF12789.7 EAX80264.1 - 1.2e-86 284.7 63.4 2.9e-33 113.7 16.0 6.0 5 1 2 7 7 7 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX80264.1 - 0.0031 17.4 4.1 0.0067 16.3 3.8 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX80264.1 - 0.025 14.3 0.1 0.07 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TTRAP PF14203.6 EAX80264.1 - 3.4 7.7 6.5 31 4.6 1.0 4.7 1 1 4 5 5 5 0 Putative tranposon-transfer assisting protein DNA_pol_B_2 PF03175.13 EAX80265.1 - 2.9e-25 89.1 4.4 3.2e-25 88.9 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX80265.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX80266.1 - 2.4e-10 39.9 2.9 2.4e-10 39.9 2.9 2.3 1 1 0 3 3 3 1 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX80266.1 - 0.089 12.3 0.7 0.19 11.3 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX80266.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PhaP_Bmeg PF09602.10 EAX80266.1 - 0.12 12.3 0.1 1.4 8.9 0.1 2.2 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4108 PF13390.6 EAX80267.1 - 1.4e-52 177.4 6.0 1.6e-52 177.3 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX80268.1 - 5.1e-12 45.7 24.4 9.6e-07 28.8 3.4 4.6 5 0 0 5 5 5 3 Phage tail repeat like KIAA1430 PF13879.6 EAX80269.1 - 1.5e-15 57.8 3.9 1.5e-15 57.8 3.9 6.1 2 1 0 2 2 2 1 KIAA1430 homologue DUF1731 PF08338.11 EAX80270.1 - 0.11 12.4 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PTR PF12789.7 EAX80271.1 - 4.1e-14 52.4 35.7 8.4e-08 32.2 5.0 6.0 6 0 0 6 6 6 4 Phage tail repeat like LIFR_D2 PF17971.1 EAX80271.1 - 0.0003 20.9 0.3 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain PatG_C PF18065.1 EAX80271.1 - 0.041 13.8 0.0 3.7 7.5 0.0 3.0 2 0 0 2 2 2 0 PatG C-terminal Trypan_PARP PF05887.11 EAX80272.1 - 0.029 14.4 8.5 0.045 13.7 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX80273.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80273.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX80274.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) F5_F8_type_C PF00754.25 EAX80276.1 - 0.00012 22.2 0.0 0.00041 20.5 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain RuBisCO_large_N PF02788.16 EAX80276.1 - 0.15 12.2 0.2 0.26 11.5 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain PTR PF12789.7 EAX80277.1 - 8.4e-10 38.6 42.8 2.5e-08 33.8 5.3 6.8 6 1 0 6 6 6 3 Phage tail repeat like Cas_Csm6 PF09659.10 EAX80277.1 - 1e-06 27.8 12.4 0.025 13.4 3.2 3.3 1 1 2 3 3 3 3 CRISPR-associated protein (Cas_Csm6) Ribosomal_S4e PF00900.20 EAX80277.1 - 4.2e-06 26.6 0.6 4.2 7.4 0.0 4.0 3 0 0 3 3 3 3 Ribosomal family S4e PatG_C PF18065.1 EAX80277.1 - 0.00019 21.4 1.1 4.1 7.4 0.0 3.8 3 0 0 3 3 3 2 PatG C-terminal LIFR_D2 PF17971.1 EAX80277.1 - 0.00081 19.6 0.2 6.2 7.0 0.1 3.5 3 0 0 3 3 3 1 Leukemia inhibitory factor receptor D2 domain MDD_C PF18376.1 EAX80277.1 - 0.047 13.4 5.7 19 4.9 0.1 3.8 2 1 2 4 4 4 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain HD_2 PF12917.7 EAX80277.1 - 0.19 11.5 10.0 13 5.5 0.3 4.1 4 1 1 5 5 5 0 HD containing hydrolase-like enzyme KinB_sensor PF16767.5 EAX80277.1 - 0.65 10.5 3.8 20 5.6 0.2 3.7 3 1 1 4 4 4 0 Sensor domain of alginate biosynthesis sensor protein KinB Gly-zipper_Omp PF13488.6 EAX80278.1 - 0.02 14.9 10.4 0.035 14.1 10.4 1.4 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX80278.1 - 0.52 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Spo12 PF05032.12 EAX80279.1 - 0.55 10.2 8.3 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF1493 PF07377.12 EAX80280.1 - 0.019 15.4 1.6 0.026 15.0 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX80281.1 - 9.3e-32 108.9 8.0 9.3e-32 108.9 8.0 3.0 3 0 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX80281.1 - 0.045 13.5 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX80281.1 - 0.46 10.1 10.4 0.28 10.8 3.7 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) DUF240 PF03086.14 EAX80281.1 - 2.4 8.1 8.1 1.3 8.9 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF1910 PF08928.10 EAX80282.1 - 0.029 14.4 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF1493 PF07377.12 EAX80282.1 - 0.089 13.3 0.1 0.092 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) RRF PF01765.19 EAX80282.1 - 0.13 12.2 0.3 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor TFIIA PF03153.13 EAX80284.1 - 0.21 11.6 8.9 0.24 11.4 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EAX80284.1 - 2.8 6.5 6.9 3.2 6.3 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_B_2 PF03175.13 EAX80285.1 - 3.4e-29 102.0 6.3 4.6e-29 101.6 6.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX80286.1 - 4.7e-10 38.9 1.6 6.1e-10 38.6 1.1 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Amidase02_C PF12123.8 EAX80287.1 - 0.0096 15.6 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX80288.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein Pox_Ag35 PF03286.14 EAX80289.1 - 0.49 10.2 5.9 0.69 9.7 5.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ARA70 PF12489.8 EAX80290.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3839 PF12943.7 EAX80291.1 - 6.3e-155 513.7 14.4 7.4e-155 513.5 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX80291.1 - 0.07 13.6 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX80291.1 - 0.23 11.9 6.0 4.6 7.8 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80291.1 - 0.35 11.4 4.9 0.6 10.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5398 PF17376.2 EAX80291.1 - 2.2 9.0 5.1 3 8.5 0.1 3.2 2 2 2 4 4 4 0 Family of unknown function (DUF5398) Pox_A32 PF04665.12 EAX80292.1 - 2.2e-07 30.6 2.1 3.2e-07 30.1 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80292.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80292.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80292.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80292.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX80292.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX80292.1 - 0.6 10.3 8.4 5.8 7.1 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX80293.1 - 1e-06 28.4 2.0 1.2e-06 28.2 2.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80293.1 - 0.0037 16.9 0.2 0.0044 16.7 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80293.1 - 0.028 13.9 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80293.1 - 0.046 13.5 0.1 0.29 10.8 0.0 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80293.1 - 0.11 12.5 1.1 0.93 9.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) Podoplanin PF05808.11 EAX80294.1 - 0.013 15.7 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Podoplanin PGP_phosphatase PF09419.10 EAX80294.1 - 0.028 14.0 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase nsp7 PF08716.10 EAX80294.1 - 0.23 12.1 1.2 0.53 10.9 0.1 2.1 2 1 0 2 2 2 0 nsp7 replicase CoatB PF10389.9 EAX80294.1 - 0.23 11.3 2.3 0.41 10.5 2.3 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B EphA2_TM PF14575.6 EAX80294.1 - 0.42 11.5 2.2 7.4 7.5 0.4 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4108 PF13390.6 EAX80295.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX80295.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX80296.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX80297.1 - 3.6e-05 24.1 0.1 0.00023 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80297.1 - 6.2e-05 23.1 2.5 0.00011 22.3 2.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX80297.1 - 8.6e-05 22.3 0.2 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX80297.1 - 0.00039 20.2 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80297.1 - 0.00068 19.5 0.5 0.0019 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80297.1 - 0.0085 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80297.1 - 0.059 12.8 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX80297.1 - 0.067 13.6 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX80297.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX80297.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX80297.1 - 0.16 12.2 3.9 6.2 7.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX80297.1 - 1.1 9.7 4.7 0.44 11.0 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 PSP PF04046.16 EAX80299.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX80300.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX80303.1 - 1.1e-155 516.1 13.3 1.4e-155 515.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80303.1 - 3.7 8.1 7.6 1.7 9.1 0.4 3.1 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80303.1 - 4.1 8.0 6.4 1.6 9.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX80304.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80304.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80304.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80304.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80304.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80304.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX80305.1 - 5.1e-35 119.7 0.7 1e-34 118.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80305.1 - 0.053 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX80305.1 - 0.51 10.4 4.0 1.9 8.5 0.5 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Chal_sti_synt_N PF00195.19 EAX80306.1 - 0.066 12.6 0.2 0.12 11.7 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX80306.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF4107 PF13389.6 EAX80307.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80307.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta ResIII PF04851.15 EAX80308.1 - 3.2e-05 24.0 0.5 5.6e-05 23.2 0.4 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX80308.1 - 0.00038 20.7 0.0 0.00075 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX80308.1 - 0.00062 19.6 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80308.1 - 0.0028 17.5 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80308.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80308.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX80308.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2939 PF11159.8 EAX80310.1 - 0.015 15.7 0.2 0.022 15.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX80311.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX80315.1 - 4.3e-05 23.9 2.8 0.00025 21.5 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX80316.1 - 3.1e-45 153.6 1.6 3.7e-45 153.4 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX80318.1 - 2.3e-05 24.5 0.1 3.1e-05 24.1 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80318.1 - 0.00048 20.0 0.0 0.00067 19.5 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80318.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX80318.1 - 0.0017 18.6 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80318.1 - 0.0046 17.3 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80318.1 - 0.025 14.0 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX80318.1 - 0.057 13.0 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX80318.1 - 0.078 12.7 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX80318.1 - 0.14 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX80319.1 - 1.5e-157 522.2 13.1 1.9e-157 521.9 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX80319.1 - 0.08 13.2 1.8 11 6.4 0.1 3.8 3 1 0 3 3 3 0 Tup N-terminal Rx_N PF18052.1 EAX80319.1 - 0.091 13.0 0.9 2.8 8.3 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain Fez1 PF06818.15 EAX80319.1 - 0.11 12.9 2.0 0.2 12.1 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80319.1 - 0.24 11.9 4.9 2.1 8.9 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80319.1 - 3.8 8.1 6.4 0.61 10.6 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX80320.1 - 9.9e-07 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80322.1 - 2.3e-155 515.1 14.4 2.7e-155 514.9 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80322.1 - 0.2 11.5 2.6 0.32 10.8 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80322.1 - 0.24 11.7 6.5 0.48 10.7 0.1 3.3 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX80322.1 - 0.42 11.1 6.9 1.8 9.1 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX80323.1 - 8.6e-07 29.4 0.3 1.6e-06 28.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF2400 PF09674.10 EAX80326.1 - 0.05 13.6 0.3 0.074 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX80326.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX80327.1 - 3.8e-156 517.7 13.7 4.8e-156 517.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80327.1 - 0.11 12.4 0.8 0.41 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX80327.1 - 0.94 10.0 4.7 1.7 9.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80327.1 - 6.5 7.3 8.5 2.8 8.5 1.0 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80328.1 - 1.1e-125 418.0 6.4 1.2e-125 417.8 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ComA PF02679.15 EAX80329.1 - 0.037 13.5 0.4 0.04 13.4 0.4 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX80329.1 - 0.2 11.1 0.3 0.34 10.3 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX80330.1 - 9.3e-157 519.7 14.2 1.2e-156 519.4 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80330.1 - 0.039 14.2 0.5 2.7 8.3 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX80330.1 - 0.05 14.0 4.0 0.72 10.3 0.1 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX80330.1 - 0.061 13.8 1.9 0.2 12.1 0.4 2.1 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX80330.1 - 0.15 11.5 0.6 0.48 9.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Tup_N PF08581.10 EAX80330.1 - 0.8 10.1 5.5 11 6.4 0.1 3.8 4 2 1 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX80331.1 - 2.3e-26 91.8 1.2 3.5e-26 91.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80331.1 - 0.072 13.7 0.0 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX80331.1 - 0.26 12.0 2.6 13 6.5 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX80332.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80332.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80332.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80332.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX80333.1 - 2.3e-34 117.6 0.6 4.4e-34 116.7 0.0 1.7 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80333.1 - 0.027 15.1 0.0 0.06 14.0 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family PAS_7 PF12860.7 EAX80333.1 - 0.16 12.1 1.6 1.5 9.0 0.2 2.1 2 0 0 2 2 2 0 PAS fold DUF4107 PF13389.6 EAX80334.1 - 2.7e-33 115.4 1.8 3.9e-33 114.9 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX80335.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80335.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80335.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80335.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX80336.1 - 2.2e-06 28.1 0.0 5.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80336.1 - 0.011 15.3 0.2 0.063 12.8 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain KIAA1430 PF13879.6 EAX80337.1 - 0.0049 17.6 0.9 0.0062 17.3 0.9 1.2 1 0 0 1 1 1 1 KIAA1430 homologue DUF745 PF05335.13 EAX80339.1 - 0.021 14.6 3.6 0.027 14.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 EAX80339.1 - 0.026 14.8 2.7 0.038 14.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) MitMem_reg PF13012.6 EAX80339.1 - 0.033 14.6 0.6 0.057 13.8 0.3 1.6 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function SMBP PF16785.5 EAX80339.1 - 0.035 14.3 1.4 0.047 13.9 1.4 1.2 1 0 0 1 1 1 0 Small metal-binding protein Syntaxin-6_N PF09177.11 EAX80339.1 - 0.037 14.6 1.4 0.053 14.1 1.4 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal COG5 PF10392.9 EAX80339.1 - 0.049 13.8 2.0 0.26 11.4 1.2 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 MCPsignal PF00015.21 EAX80339.1 - 0.077 12.8 0.4 0.098 12.5 0.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tweety PF04906.13 EAX80339.1 - 0.1 11.2 0.2 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Tweety BRE1 PF08647.11 EAX80339.1 - 0.17 12.0 8.7 0.24 11.5 8.2 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 EAX80339.1 - 0.27 11.4 1.9 0.41 10.9 0.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 EAX80339.1 - 0.35 10.1 3.1 0.44 9.8 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EAX80339.1 - 0.54 10.3 8.9 6.7 6.7 8.9 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin_2 PF14523.6 EAX80339.1 - 0.55 10.6 4.9 6.9 7.1 4.8 2.3 1 1 0 1 1 1 0 Syntaxin-like protein YtxH PF12732.7 EAX80339.1 - 2.2 8.9 4.6 5.9 7.5 4.6 2.0 1 1 0 1 1 1 0 YtxH-like protein IBD PF10416.9 EAX80340.1 - 3.5e-13 49.7 0.0 6.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD KilA-N PF04383.13 EAX80341.1 - 7.3e-35 119.2 0.2 1.9e-34 117.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80341.1 - 0.034 14.8 0.0 0.084 13.5 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family RHH_3 PF12651.7 EAX80342.1 - 0.01 15.8 0.2 0.018 15.0 0.0 1.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Tho1_MOS11_C PF18592.1 EAX80342.1 - 0.094 12.5 0.0 3.3 7.6 0.0 2.7 2 1 1 3 3 3 0 Tho1/MOS11 C-terminal domain Cep57_MT_bd PF06657.13 EAX80343.1 - 0.017 15.6 14.9 0.46 11.0 0.2 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EAX80343.1 - 0.58 9.5 15.4 16 4.7 15.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 EAX80343.1 - 3 8.1 22.9 0.21 11.8 3.6 3.0 1 1 2 3 3 3 0 Flagellar FliJ protein Pox_A32 PF04665.12 EAX80344.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80344.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80344.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80344.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80344.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80344.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX80346.1 - 5.4e-55 185.2 6.0 6e-55 185.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX80346.1 - 0.085 13.1 0.1 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4106 PF13388.6 EAX80347.1 - 3.3e-211 701.9 21.6 5.7e-211 701.1 21.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX80347.1 - 0.1 12.2 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4107 PF13389.6 EAX80350.1 - 1.1e-69 233.7 4.1 1.4e-69 233.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX80351.1 - 4.1e-28 98.5 6.8 9e-28 97.3 6.8 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX80351.1 - 0.61 10.1 6.1 7.2 6.7 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF5065) DUF4107 PF13389.6 EAX80354.1 - 1.1e-29 103.7 4.7 6e-28 98.0 4.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80355.1 - 4.7e-80 268.5 10.3 6e-80 268.2 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80355.1 - 0.11 13.1 0.6 0.18 12.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX80357.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80358.1 - 8.9e-05 22.9 3.2 0.00045 20.7 3.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80358.1 - 0.02 15.5 0.1 0.043 14.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX80358.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX80358.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2939 PF11159.8 EAX80359.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX80359.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX80360.1 - 0.0091 16.0 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta T5orf172 PF10544.9 EAX80361.1 - 0.00018 22.0 0.2 0.00042 20.8 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80361.1 - 0.014 15.2 0.2 0.039 13.8 0.2 1.8 1 1 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX80362.1 - 9.1e-80 267.6 11.0 1.2e-79 267.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX80363.1 - 0.0036 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Apolipoprotein PF01442.18 EAX80364.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3781 PF12636.7 EAX80365.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Trypan_PARP PF05887.11 EAX80366.1 - 0.063 13.3 14.5 0.1 12.5 14.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC27 PF09507.10 EAX80366.1 - 7.6 5.8 12.3 10 5.4 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3839 PF12943.7 EAX80367.1 - 7.8e-156 516.7 13.7 9.7e-156 516.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80367.1 - 0.17 11.8 1.1 0.49 10.2 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX80367.1 - 3.2 8.3 5.9 1.4 9.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80367.1 - 3.2 8.3 6.7 5 7.7 0.3 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX80369.1 - 1.4e-42 144.0 0.8 2.6e-42 143.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80369.1 - 0.0094 16.6 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family PTR PF12789.7 EAX80371.1 - 7.7e-18 64.3 1.9 7.7e-18 64.3 1.9 4.4 5 1 0 5 5 5 1 Phage tail repeat like TbpB_A PF17484.2 EAX80371.1 - 0.044 14.6 4.5 0.13 13.0 3.5 2.2 2 1 0 2 2 2 0 N-Lobe handle Tf-binding protein B YmaF PF12788.7 EAX80371.1 - 1.6 9.3 10.2 29 5.3 0.1 3.7 2 2 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX80371.1 - 2.8 8.4 14.9 4.8 7.6 0.3 4.3 4 0 0 4 4 4 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAX80373.1 - 2.3e-07 30.6 2.9 3.4e-07 30.0 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80373.1 - 0.0045 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80373.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80373.1 - 0.063 13.0 0.2 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80373.1 - 0.2 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80373.1 - 0.44 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX80374.1 - 8.9e-16 57.7 0.5 2.7e-15 56.2 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX80374.1 - 0.0029 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Trypan_PARP PF05887.11 EAX80375.1 - 0.042 13.8 6.8 0.051 13.5 6.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80375.1 - 7.2 7.1 5.7 8.6 6.8 5.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX80378.1 - 0.058 12.4 0.2 0.059 12.3 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TPR_MLP1_2 PF07926.12 EAX80380.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX80380.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX80380.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Trypan_PARP PF05887.11 EAX80381.1 - 0.013 15.4 8.3 0.016 15.2 8.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80381.1 - 0.95 9.9 5.7 1.1 9.7 5.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX80382.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80382.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX80383.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX80383.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF3839 PF12943.7 EAX80384.1 - 2.2e-157 521.8 14.9 2.7e-157 521.4 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80384.1 - 0.78 10.2 7.0 2.5 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX80385.1 - 3.6e-06 27.5 0.3 7.7e-06 26.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80386.1 - 1.2e-41 141.1 4.9 6.4e-41 138.7 2.3 2.6 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80386.1 - 0.0072 16.9 0.0 0.028 15.0 0.0 2.0 1 0 0 1 1 1 1 Parathyroid hormone family DUF4107 PF13389.6 EAX80388.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80388.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX80389.1 - 6.8e-38 130.5 4.2 9.1e-38 130.1 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX80389.1 - 0.04 14.2 1.9 0.19 12.1 0.1 2.1 1 1 1 2 2 2 0 PRD domain DUF3839 PF12943.7 EAX80390.1 - 3.7e-103 344.2 6.2 4.2e-103 344.0 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX80392.1 - 3.3e-22 78.3 17.2 1.6e-16 60.1 1.3 4.2 5 0 0 5 5 5 2 Phage tail repeat like DUF4738 PF15889.5 EAX80392.1 - 0.13 12.1 3.0 0.27 11.1 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) GPS2_interact PF15784.5 EAX80394.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80394.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80395.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4795 PF16043.5 EAX80396.1 - 0.023 14.3 18.5 1.6 8.3 1.2 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX80396.1 - 2.3 8.6 9.8 0.5 10.7 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat DUF4108 PF13390.6 EAX80397.1 - 8.6e-58 194.3 4.2 9.5e-58 194.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX80398.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX80399.1 - 3.6e-05 23.8 1.9 6.9e-05 22.9 1.9 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80399.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX80399.1 - 0.00036 20.8 0.0 0.00061 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80399.1 - 0.00096 19.0 1.1 0.0027 17.5 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80399.1 - 0.0071 16.7 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EAX80399.1 - 0.029 14.1 0.8 0.045 13.4 0.3 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase PhoH PF02562.16 EAX80399.1 - 0.042 13.3 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX80399.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX80399.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX80399.1 - 0.25 11.0 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX80399.1 - 0.74 10.3 4.2 0.3 11.5 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1827 PF08860.10 EAX80399.1 - 0.81 10.0 4.2 4.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) NYD-SP28 PF14772.6 EAX80399.1 - 1.9 8.6 9.0 2.1 8.5 1.5 2.6 3 0 0 3 3 3 0 Sperm tail DUF4107 PF13389.6 EAX80400.1 - 2.2e-64 216.5 2.8 2.8e-64 216.2 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX80401.1 - 2.6e-10 40.2 24.7 1.3e-08 34.8 0.5 6.2 5 1 0 5 5 5 3 Phage tail repeat like DUF4108 PF13390.6 EAX80402.1 - 5.7e-62 207.9 5.6 6.3e-62 207.7 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX80402.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Trypan_PARP PF05887.11 EAX80404.1 - 0.06 13.3 10.1 0.089 12.8 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX80406.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX80408.1 - 0.042 14.3 0.9 0.058 13.8 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TALPID3 PF15324.6 EAX80409.1 - 0.45 8.1 13.5 0.56 7.8 13.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX80409.1 - 7.6 7.0 6.6 11 6.5 6.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX80410.1 - 7.3e-151 500.4 13.4 8.5e-151 500.2 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80410.1 - 0.047 14.0 0.7 3.2 8.1 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain DUF5398 PF17376.2 EAX80410.1 - 0.9 10.2 0.1 0.9 10.2 0.1 3.2 3 2 1 4 4 4 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX80410.1 - 3.6 8.1 6.6 1.6 9.2 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX80411.1 - 0.064 13.7 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX80411.1 - 0.42 10.7 3.4 10 6.2 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX80412.1 - 7.7e-52 173.2 38.8 8.5e-33 112.2 16.8 3.0 3 1 1 4 4 4 2 Phage tail repeat like BppL_N PF18338.1 EAX80413.1 - 2.1e-05 24.1 0.2 41 4.2 0.0 5.6 4 0 0 4 4 4 0 Lower baseplate protein N-terminal domain Chordopox_G3 PF06129.12 EAX80413.1 - 4.8e-05 24.0 21.3 9.1 7.0 0.2 6.1 6 0 0 6 6 6 4 Chordopoxvirus G3 protein RraB PF06877.11 EAX80413.1 - 6.7e-05 23.5 0.4 1.2e+02 3.5 0.0 5.1 5 0 0 5 5 5 0 Regulator of ribonuclease activity B DUF3416 PF11896.8 EAX80413.1 - 0.00011 22.6 1.2 91 3.3 0.0 5.7 5 1 1 6 6 6 0 Domain of unknown function (DUF3416) UL41A PF17591.2 EAX80413.1 - 0.00013 21.9 1.4 86 3.3 0.0 5.2 5 0 0 5 5 5 0 Herpesvirus UL41A DUF4980 PF16352.5 EAX80413.1 - 0.0011 19.0 12.5 15 5.7 0.1 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF4980) DUF3474 PF11960.8 EAX80413.1 - 0.0021 18.3 19.2 16 5.7 0.1 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF3474) MVP_shoulder PF11978.8 EAX80413.1 - 0.0076 16.3 6.7 1.5e+02 2.4 0.0 6.1 6 0 0 6 6 6 0 Shoulder domain TQ PF18202.1 EAX80413.1 - 0.011 16.2 55.9 2.1 8.9 4.5 6.4 2 2 4 6 6 6 0 T-Q ester bond containing domain DsbC_N PF10411.9 EAX80413.1 - 0.016 14.6 0.9 1.3e+02 2.1 0.0 4.4 4 0 0 4 4 4 0 Disulfide bond isomerase protein N-terminus TERB2 PF15101.6 EAX80413.1 - 0.04 14.0 15.2 37 4.3 0.1 5.2 5 0 0 5 5 5 0 Telomere-associated protein TERB2 LOR PF04525.12 EAX80413.1 - 0.051 13.2 20.0 17 5.0 0.2 5.2 5 0 0 5 5 5 0 LURP-one-related Kunitz_legume PF00197.18 EAX80413.1 - 0.055 13.4 17.9 26 4.7 0.2 5.4 5 0 0 5 5 5 0 Trypsin and protease inhibitor PQQ PF01011.21 EAX80413.1 - 0.17 11.9 17.4 1.1e+02 3.0 0.1 7.0 6 0 0 6 6 6 0 PQQ enzyme repeat DUF2206 PF09971.9 EAX80413.1 - 1.9 7.2 35.9 2.3 6.9 1.2 5.0 5 0 0 5 5 5 0 Predicted membrane protein (DUF2206) DNA_pol_B_2 PF03175.13 EAX80414.1 - 1.1e-22 80.6 3.7 1.4e-22 80.2 3.7 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX80414.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX80416.1 - 9.2e-21 74.2 4.9 1.1e-20 74.0 4.9 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX80417.1 - 8.9e-25 86.5 32.5 1.5e-24 85.8 8.6 6.2 5 1 1 6 6 5 2 Phage tail repeat like Glyco_hydro_30 PF02055.16 EAX80418.1 - 7.2e-19 68.0 2.7 1e-18 67.5 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EAX80418.1 - 1.7e-07 31.4 2.1 3.1e-07 30.5 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain KilA-N PF04383.13 EAX80419.1 - 4.7e-42 142.4 1.2 6.3e-42 142.0 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80419.1 - 0.013 16.1 0.1 0.039 14.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF4107 PF13389.6 EAX80420.1 - 1.7e-45 155.1 8.1 1.2e-43 149.0 8.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_D5 PF03288.16 EAX80421.1 - 5.8e-05 23.5 2.5 0.00041 20.8 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like T5orf172 PF10544.9 EAX80422.1 - 6.5e-05 23.4 0.1 0.00015 22.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Bacillus_HBL PF05791.11 EAX80423.1 - 0.051 13.4 8.5 0.56 10.0 3.7 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YlqD PF11068.8 EAX80423.1 - 0.09 13.2 7.9 0.64 10.4 5.5 2.2 2 0 0 2 2 2 0 YlqD protein HMw1_D2 PF18254.1 EAX80423.1 - 0.094 13.1 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 HMW1 domain 2 TolA_bind_tri PF16331.5 EAX80423.1 - 0.2 11.7 3.7 0.32 11.1 0.8 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Enkurin PF13864.6 EAX80423.1 - 0.94 9.9 7.8 1.1 9.8 1.3 2.8 1 1 1 2 2 2 0 Calmodulin-binding BLOC1_2 PF10046.9 EAX80423.1 - 1.2 9.5 7.0 16 5.9 6.9 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 EAX80423.1 - 2.3 8.2 8.8 2.5 8.1 6.7 2.1 2 1 0 2 2 2 0 FlxA-like protein FTHFS PF01268.19 EAX80424.1 - 0.13 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Herpes_UL25 PF01499.16 EAX80425.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family TAF4 PF05236.14 EAX80426.1 - 0.0038 17.0 11.5 0.0038 17.0 11.5 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 EAX80426.1 - 0.023 13.0 9.5 0.03 12.6 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4106 PF13388.6 EAX80427.1 - 2.8e-277 919.6 20.0 2.8e-277 919.6 20.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80427.1 - 0.0012 19.1 0.2 0.049 13.9 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated FliD_N PF02465.18 EAX80429.1 - 0.16 12.7 2.3 0.25 12.1 2.3 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF3839 PF12943.7 EAX80431.1 - 2.8e-26 92.4 4.0 4.3e-26 91.8 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX80432.1 - 2.6e-06 27.9 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80432.1 - 0.018 14.9 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX80433.1 - 5.5e-151 500.8 12.6 6.8e-151 500.5 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80433.1 - 0.054 13.0 3.3 0.042 13.3 0.4 2.0 1 1 0 2 2 2 0 Z1 domain KELK PF15796.5 EAX80433.1 - 1.4 9.4 4.8 2.3 8.7 0.6 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX80435.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80435.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX80437.1 - 4.7e-121 402.8 12.1 5.8e-121 402.5 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80437.1 - 0.032 14.7 2.9 1.8 9.0 0.0 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX80438.1 - 1.8e-69 235.0 2.1 2.1e-69 234.8 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4107 PF13389.6 EAX80440.1 - 7.2e-71 237.6 3.7 1.1e-70 237.0 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Annexin PF00191.20 EAX80441.1 - 0.2 11.7 1.3 0.86 9.7 0.3 2.6 2 1 0 2 2 2 0 Annexin TMA7 PF09072.10 EAX80442.1 - 0.17 12.7 1.9 0.21 12.5 0.5 1.8 2 0 0 2 2 2 0 Translation machinery associated TMA7 HNH_3 PF13392.6 EAX80443.1 - 2.4e-07 30.4 0.4 4.3e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 HNH endonuclease RVT_N PF13655.6 EAX80443.1 - 0.088 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase DUF3839 PF12943.7 EAX80444.1 - 6.4e-156 516.9 14.5 8.1e-156 516.6 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80444.1 - 0.26 11.6 2.8 1.3 9.3 0.1 3.1 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX80444.1 - 0.39 11.2 7.2 2 8.9 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80444.1 - 0.44 11.1 4.4 1.2 9.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX80444.1 - 4.1 7.8 6.6 15 6.0 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal DUF4107 PF13389.6 EAX80445.1 - 3.4e-49 167.1 2.9 5e-49 166.6 2.9 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) GGDEF PF00990.21 EAX80446.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX80447.1 - 1.7e-56 190.1 6.9 1.9e-56 190.0 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80448.1 - 1.4e-05 25.5 2.6 7.5e-05 23.1 2.6 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80448.1 - 0.039 14.6 0.1 0.076 13.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX80448.1 - 0.091 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAX80449.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80449.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80449.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80449.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX80450.1 - 4.8e-07 30.3 0.1 1.1e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX80451.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80451.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80451.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80451.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80451.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80451.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX80452.1 - 2.1e-79 266.4 9.8 2.6e-79 266.1 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX80452.1 - 0.035 14.1 0.8 8.7 6.4 0.0 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 EAX80452.1 - 0.056 13.9 0.3 0.068 13.6 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX80452.1 - 0.06 13.9 0.3 0.1 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX80452.1 - 0.2 11.5 1.2 0.71 9.7 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase GalP_UDP_transf PF01087.22 EAX80452.1 - 0.24 11.8 2.0 1.2 9.6 1.3 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Ank_2 PF12796.7 EAX80453.1 - 2.3e-88 290.9 6.1 1.3e-19 70.6 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX80453.1 - 1.9e-53 177.8 0.1 3.9e-09 36.6 0.0 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX80453.1 - 1.3e-52 174.0 0.0 1.3e-06 28.6 0.0 7.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX80453.1 - 4.8e-52 173.7 0.5 1.4e-11 44.7 0.0 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX80453.1 - 5.6e-38 124.6 0.0 0.00032 20.9 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat L_protein_N PF15518.6 EAX80453.1 - 4.8e-05 23.1 0.0 7.2 6.5 0.0 4.8 2 1 1 3 3 3 2 L protein N-terminus DUF3839 PF12943.7 EAX80455.1 - 3.7e-25 88.8 5.0 6.2e-25 88.1 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX80455.1 - 0.02 15.1 0.7 0.061 13.6 0.1 2.0 1 1 1 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX80456.1 - 5.3e-05 22.8 3.2 7.7e-05 22.3 3.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX80456.1 - 0.004 17.2 0.1 0.0094 16.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX80456.1 - 0.017 14.7 0.2 0.034 13.7 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX80456.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF5588 PF17826.1 EAX80458.1 - 0.0042 16.0 0.7 0.0058 15.6 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) DUF745 PF05335.13 EAX80458.1 - 0.099 12.4 9.5 0.12 12.1 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) SH3_14 PF18343.1 EAX80458.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Dda helicase SH3 domain PCRF PF03462.18 EAX80458.1 - 0.12 12.2 5.1 0.16 11.8 5.1 1.2 1 0 0 1 1 1 0 PCRF domain Fib_alpha PF08702.10 EAX80458.1 - 0.15 12.2 11.9 0.22 11.7 8.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.11 EAX80458.1 - 0.31 11.1 7.0 0.41 10.7 7.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Herpes_UL6 PF01763.16 EAX80458.1 - 0.36 9.3 5.6 0.42 9.1 5.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Bap31_Bap29_C PF18035.1 EAX80458.1 - 0.36 10.9 0.3 0.36 10.9 0.3 3.0 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Tropomyosin_1 PF12718.7 EAX80458.1 - 0.44 10.7 15.6 0.61 10.2 15.6 1.3 1 0 0 1 1 1 0 Tropomyosin like CTU2 PF10288.9 EAX80458.1 - 0.44 10.8 4.7 0.53 10.6 0.0 2.4 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 V_ATPase_I PF01496.19 EAX80458.1 - 1.4 6.8 6.2 1.5 6.7 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 EAX80458.1 - 1.4 8.7 11.2 1.8 8.3 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 EAX80458.1 - 3.3 7.1 18.6 4.4 6.7 16.3 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4061 PF13270.6 EAX80458.1 - 4.3 7.7 9.2 0.32 11.3 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) GrpE PF01025.19 EAX80458.1 - 5.5 6.6 15.3 5 6.8 7.9 2.0 1 1 1 2 2 2 0 GrpE CorA PF01544.18 EAX80458.1 - 6 6.1 10.2 7.9 5.7 10.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EAX80458.1 - 8 5.9 10.5 9.1 5.7 10.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KilA-N PF04383.13 EAX80459.1 - 5.6e-07 29.4 0.3 1.3e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80460.1 - 4.9e-152 504.2 11.1 6.7e-152 503.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX80460.1 - 0.028 14.8 0.3 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX80460.1 - 0.54 10.8 4.4 2.1 8.8 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX80461.1 - 3.3e-30 103.9 16.7 3.3e-30 103.9 16.7 4.8 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX80461.1 - 0.16 11.8 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) CAAP1 PF15335.6 EAX80463.1 - 0.89 10.1 44.9 12 6.5 0.8 7.2 7 0 0 7 7 7 0 Caspase activity and apoptosis inhibitor 1 Kinetochor_Ybp2 PF08568.10 EAX80463.1 - 1.2 7.5 31.9 2.1 6.7 0.8 6.4 1 1 6 7 7 7 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF1892 PF08987.10 EAX80464.1 - 0.00038 20.6 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1892) Leucyl-specific PF14795.6 EAX80464.1 - 0.0024 17.9 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 2 Leucine-tRNA synthetase-specific domain BTRD1 PF17660.1 EAX80464.1 - 0.0077 16.0 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 2 Bacterial tandem repeat domain 1 SCVP PF17619.2 EAX80464.1 - 0.0084 16.9 0.6 5.3 8.0 0.0 2.9 3 0 0 3 3 3 2 Secreted clade V proteins AAA PF00004.29 EAX80464.1 - 0.027 14.9 0.1 10 6.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RE_BsaWI PF18643.1 EAX80464.1 - 0.04 13.8 1.7 12 5.8 0.0 3.6 2 2 2 4 4 4 0 BsaWI restriction endonuclease type 2 Nup160 PF11715.8 EAX80464.1 - 0.062 11.9 0.1 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HlyC PF02794.16 EAX80464.1 - 0.14 12.1 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 RTX toxin acyltransferase family Calx-beta PF03160.14 EAX80464.1 - 0.15 12.2 6.1 7.7 6.7 0.3 3.5 2 2 1 3 3 3 0 Calx-beta domain RFX_DNA_binding PF02257.15 EAX80465.1 - 6.6e-05 23.5 0.2 9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX80465.1 - 0.00073 20.0 2.0 0.0011 19.4 2.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX80465.1 - 0.013 15.5 1.3 0.018 15.0 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF2939 PF11159.8 EAX80466.1 - 0.0046 17.3 0.7 0.0049 17.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) DUF1043 PF06295.12 EAX80467.1 - 0.042 13.9 0.2 0.06 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX80467.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Mo-nitro_C PF06967.11 EAX80471.1 - 5.5 7.0 8.6 1.7 8.7 2.5 2.1 1 1 1 2 2 2 0 Mo-dependent nitrogenase C-terminus DUF3839 PF12943.7 EAX80472.1 - 1.2e-115 385.1 8.9 1.4e-115 384.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80472.1 - 0.34 11.4 3.2 0.8 10.2 0.9 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80473.1 - 1e-108 362.4 6.6 1.2e-108 362.2 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX80474.1 - 3.3e-52 176.2 5.5 3.7e-52 176.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Spo12 PF05032.12 EAX80476.1 - 0.53 10.2 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Chal_sti_synt_N PF00195.19 EAX80477.1 - 0.023 14.1 0.7 0.046 13.1 0.7 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Armet PF10208.9 EAX80477.1 - 0.038 13.9 0.3 0.038 13.9 0.3 1.9 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding EssA PF10661.9 EAX80477.1 - 2.4 8.0 8.5 6.6 6.6 8.5 1.7 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX80480.1 - 2.9e-154 511.5 12.6 3.6e-154 511.2 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80480.1 - 0.19 11.5 1.3 0.53 10.1 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80480.1 - 0.97 9.8 4.9 8.3 6.8 0.0 3.5 2 2 1 3 3 3 0 Rx N-terminal domain Glu-tRNAGln PF02686.15 EAX80480.1 - 1 9.7 3.5 0.68 10.3 0.2 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF1043 PF06295.12 EAX80482.1 - 0.022 14.7 0.2 0.028 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX80482.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX80485.1 - 1.1e-71 240.2 3.7 1.5e-71 239.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX80486.1 - 6.3e-29 100.1 2.2 6.8e-29 100.0 0.4 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX80487.1 - 7.6e-07 28.8 2.0 7.6e-07 28.8 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80487.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80487.1 - 3.8e-05 23.5 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80487.1 - 0.00016 21.7 3.4 0.00039 20.5 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80487.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX80487.1 - 0.0014 18.3 0.5 0.0097 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX80487.1 - 0.0015 18.3 0.5 0.0039 17.0 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80487.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX80487.1 - 0.069 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80487.1 - 0.09 13.2 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80487.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX80487.1 - 0.24 11.8 3.2 0.73 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX80487.1 - 0.38 11.0 4.1 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX80489.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TPR_MLP1_2 PF07926.12 EAX80492.1 - 0.0083 16.2 0.3 0.01 15.9 0.3 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX80492.1 - 0.081 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX80492.1 - 0.96 9.4 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family PPDK_N PF01326.19 EAX80494.1 - 1.8e-57 195.1 0.0 3e-31 108.9 0.0 3.1 2 1 1 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EAX80494.1 - 1.4e-22 79.2 0.4 3.1e-22 78.0 0.4 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEP-utilizers_C PF02896.18 EAX80494.1 - 0.00014 21.1 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain DUF1493 PF07377.12 EAX80495.1 - 0.02 15.4 0.6 0.039 14.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX80496.1 - 4e-59 196.5 38.3 4.3e-34 116.4 15.9 4.4 3 2 1 4 4 4 2 Phage tail repeat like RACo_linker PF17650.1 EAX80496.1 - 0.013 15.3 0.4 1.7 8.6 0.0 3.2 3 1 1 4 4 4 0 RACo linker region DUF4116 PF13475.6 EAX80496.1 - 0.031 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX80496.1 - 0.52 10.7 6.1 25 5.3 0.8 4.0 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain KilA-N PF04383.13 EAX80497.1 - 6.1e-10 38.9 0.4 1.1e-09 38.1 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80498.1 - 7.2e-143 474.2 13.8 8.9e-143 473.9 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX80498.1 - 0.068 13.5 2.4 8.9 6.7 0.1 3.7 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX80498.1 - 1.1 9.7 6.3 1.6 9.2 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX80499.1 - 3.1e-41 139.7 0.6 6.4e-41 138.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80499.1 - 0.017 15.3 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX80499.1 - 0.037 13.3 0.1 0.13 11.5 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX80499.1 - 0.13 10.8 0.1 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Amidase02_C PF12123.8 EAX80500.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX80501.1 - 2.1e-158 525.0 14.5 2.5e-158 524.8 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80501.1 - 1.8 9.1 7.9 2 8.9 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDR PF08841.10 EAX80505.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX80507.1 - 0.0026 17.4 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX80508.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX80509.1 - 8e-06 25.5 1.7 8e-06 25.5 1.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80509.1 - 2.5e-05 24.6 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80509.1 - 3.1e-05 23.8 0.3 0.29 10.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80509.1 - 0.00013 22.0 3.3 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80509.1 - 0.0005 19.9 0.1 0.00095 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80509.1 - 0.0015 18.3 0.7 0.0042 16.9 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80509.1 - 0.0016 18.1 0.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80509.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX80509.1 - 0.058 13.0 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX80509.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX80509.1 - 0.071 13.5 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80509.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX80509.1 - 0.11 12.5 0.8 1.7 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX80509.1 - 0.44 10.8 4.6 9.1 6.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Tctex-1 PF03645.13 EAX80510.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Tctex-1 family Trypan_PARP PF05887.11 EAX80511.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80511.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX80512.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80512.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX80513.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX80514.1 - 5.8e-79 265.0 10.1 7.4e-79 264.6 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX80514.1 - 0.067 13.4 0.2 0.16 12.2 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF29 Pox_A32 PF04665.12 EAX80515.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80515.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80515.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80515.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80515.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80515.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80515.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80515.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX80515.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80515.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80515.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80515.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1043 PF06295.12 EAX80517.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX80518.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX80518.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX80518.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein PSP PF04046.16 EAX80520.1 - 0.087 12.7 0.8 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX80522.1 - 0.022 15.2 0.5 0.045 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX80522.1 - 0.68 10.0 3.9 8.4 6.5 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX80523.1 - 7.8e-58 192.4 68.7 1.4e-28 98.8 21.8 4.2 2 2 3 5 5 4 3 Phage tail repeat like RACo_linker PF17650.1 EAX80523.1 - 0.018 14.9 0.2 1.3 8.9 0.1 3.1 2 1 1 3 3 3 0 RACo linker region DUF4116 PF13475.6 EAX80523.1 - 0.02 14.6 0.7 0.04 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX80523.1 - 0.025 14.9 6.7 2.4 8.6 0.3 3.4 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain Peptidase_C78 PF07910.13 EAX80523.1 - 0.084 12.3 1.7 2.4 7.6 0.3 2.4 1 1 1 2 2 2 0 Peptidase family C78 Macoilin PF09726.9 EAX80523.1 - 0.27 9.7 11.7 0.33 9.5 11.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF4404 PF14357.6 EAX80523.1 - 2.4 8.8 6.8 21 5.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Aa_trans PF01490.18 EAX80524.1 - 5.6e-12 45.1 13.7 6.8e-12 44.8 13.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.7 EAX80525.1 - 1.3e-98 323.7 64.4 1e-20 74.1 5.1 8.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAX80525.1 - 1.1e-92 300.8 18.3 1.4e-07 31.6 0.0 12.3 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.6 EAX80525.1 - 5.3e-86 282.0 22.9 4e-11 43.2 0.0 11.9 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX80525.1 - 1.2e-70 225.0 20.3 7.2e-06 26.0 0.1 12.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 EAX80525.1 - 1.5e-63 210.0 19.5 5.9e-12 45.6 0.1 8.4 5 4 3 8 8 8 8 Ankyrin repeats (many copies) YcxB PF14317.6 EAX80525.1 - 1.6e-15 56.5 1.6 1.8 8.4 0.0 7.9 8 0 0 8 8 8 6 YcxB-like protein DUF3130 PF11328.8 EAX80525.1 - 2.3e-06 27.8 9.8 12 6.2 0.0 6.6 3 2 4 7 7 7 0 Protein of unknown function (DUF3130 SH3_9 PF14604.6 EAX80525.1 - 1e-05 25.3 0.0 35 4.4 0.0 6.4 7 0 0 7 7 7 0 Variant SH3 domain KdgM PF06178.13 EAX80525.1 - 1.3e-05 25.0 11.8 1 8.9 0.2 4.3 2 2 1 3 3 3 3 Oligogalacturonate-specific porin protein (KdgM) DUF5064 PF16703.5 EAX80525.1 - 0.00026 21.4 3.1 2 8.9 0.2 3.6 2 2 1 3 3 3 2 Domain of unknown function (DUF5064) PAZ_siRNAbind PF12212.8 EAX80525.1 - 0.0087 15.9 3.1 87 3.0 0.0 6.0 2 2 6 8 8 8 0 PAZ domain Env-gp36 PF09590.10 EAX80525.1 - 0.011 14.2 10.2 1.3 7.4 0.2 3.3 1 1 1 3 3 3 0 Lentivirus surface glycoprotein DUF640 PF04852.12 EAX80525.1 - 0.019 15.1 5.4 7.9 6.7 0.0 5.7 4 3 3 7 7 7 0 Protein of unknown function (DUF640) Importin_rep_5 PF18816.1 EAX80525.1 - 0.15 12.4 19.0 53 4.2 0.1 7.1 8 0 0 8 8 7 0 Importin repeat DUF2149 PF09919.9 EAX80525.1 - 0.19 12.0 2.3 38 4.6 0.0 4.8 3 3 5 8 8 8 0 Uncharacterized conserved protein (DUF2149) RNase_PH_C PF03725.15 EAX80525.1 - 0.32 11.1 1.6 29 4.8 0.1 4.0 5 0 0 5 5 4 0 3' exoribonuclease family, domain 2 Bac_surface_Ag PF01103.23 EAX80525.1 - 0.32 10.4 7.9 0.84 9.1 2.2 2.3 2 0 0 2 2 2 0 Surface antigen PH_8 PF15409.6 EAX80525.1 - 0.78 10.1 4.0 6.3 7.2 0.1 3.8 2 2 2 4 4 4 0 Pleckstrin homology domain DUF1102 PF06510.11 EAX80525.1 - 3.3 7.9 7.6 79 3.4 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1102) DDR PF08841.10 EAX80528.1 - 0.18 10.8 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Chal_sti_synt_N PF00195.19 EAX80529.1 - 0.064 12.7 0.2 0.12 11.8 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF4108 PF13390.6 EAX80530.1 - 2.4e-65 218.8 6.8 2.6e-65 218.7 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX80531.1 - 0.37 10.7 2.8 0.83 9.6 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX80532.1 - 2.6e-05 24.2 0.6 2.6e-05 24.2 0.6 3.9 4 1 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX80532.1 - 0.0019 18.1 3.4 0.0027 17.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX80532.1 - 0.064 13.0 0.1 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX80532.1 - 0.12 12.0 12.4 0.14 11.8 8.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3417 PF11897.8 EAX80532.1 - 0.14 12.6 0.7 0.52 10.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) YmaF PF12788.7 EAX80532.1 - 0.54 10.8 2.6 1.9 9.1 0.9 2.7 2 1 0 2 2 2 0 YmaF family DUF3839 PF12943.7 EAX80533.1 - 3.9e-65 219.7 2.0 4.9e-65 219.4 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80533.1 - 0.067 12.7 0.2 0.076 12.5 0.2 1.1 1 0 0 1 1 1 0 Z1 domain MitMem_reg PF13012.6 EAX80533.1 - 0.13 12.7 0.8 0.2 12.1 0.8 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Ribosomal_L27e PF01777.18 EAX80533.1 - 0.4 11.0 2.8 22 5.5 0.1 3.0 3 0 0 3 3 3 0 Ribosomal L27e protein family F5_F8_type_C PF00754.25 EAX80535.1 - 1.4e-05 25.3 0.1 4.6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain GAS2 PF02187.17 EAX80535.1 - 0.084 13.0 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain DUF4107 PF13389.6 EAX80536.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX80538.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX80538.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase P22_AR_C PF10548.9 EAX80540.1 - 0.067 13.4 0.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain Gly_rich PF12810.7 EAX80541.1 - 2.5e-23 83.3 23.1 2.9e-23 83.0 23.1 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX80543.1 - 1.1e-154 512.9 12.2 1.4e-154 512.6 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80543.1 - 3.5 8.2 6.2 1.5 9.4 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80543.1 - 4.2 7.9 7.5 1.9 9.0 0.7 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80544.1 - 3.2e-120 400.0 12.8 4e-120 399.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX80544.1 - 0.023 14.7 0.7 5.7 7.0 0.0 2.6 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 EAX80544.1 - 0.029 14.8 0.5 0.047 14.2 0.5 1.4 1 0 0 1 1 1 0 Fez1 KELK PF15796.5 EAX80544.1 - 0.052 14.0 5.2 1.5 9.4 0.1 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX80544.1 - 0.15 11.9 1.0 0.61 9.9 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Terminase_2 PF03592.16 EAX80544.1 - 0.27 11.7 3.8 0.75 10.3 0.3 2.3 1 1 1 2 2 2 0 Terminase small subunit PRD PF00874.20 EAX80544.1 - 0.34 11.2 2.6 0.7 10.2 0.1 2.6 3 0 0 3 3 3 0 PRD domain DUF2408 PF10303.9 EAX80544.1 - 0.75 10.4 3.4 0.42 11.2 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Trypan_PARP PF05887.11 EAX80548.1 - 0.1 12.6 5.1 0.15 12.0 5.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX80550.1 - 4.5e-63 211.4 5.0 5.1e-63 211.3 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX80551.1 - 1.5e-79 266.9 10.5 1.9e-79 266.5 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX80552.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80552.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80552.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80552.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4106 PF13388.6 EAX80553.1 - 3e-96 323.2 5.4 3e-96 323.2 5.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF4106 PF13388.6 EAX80554.1 - 9.5e-99 331.5 10.1 9.5e-99 331.5 10.1 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80554.1 - 0.00016 22.0 0.4 0.015 15.6 0.4 2.8 2 1 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX80554.1 - 0.073 13.7 0.7 0.19 12.3 0.7 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX80554.1 - 6.9 7.1 17.1 7.9 6.9 0.4 4.5 4 1 1 5 5 5 0 WYL domain DUF3839 PF12943.7 EAX80555.1 - 4.4e-157 520.7 14.4 5.5e-157 520.4 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80555.1 - 0.047 14.3 4.6 0.2 12.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80555.1 - 0.45 11.0 5.3 2.1 8.8 1.0 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX80557.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX80557.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX80557.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX80558.1 - 5e-63 211.3 6.1 5.6e-63 211.1 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX80559.1 - 0.0067 16.0 22.2 0.6 9.7 1.4 4.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) SEP PF08059.13 EAX80559.1 - 0.19 12.3 1.7 8.7 7.0 0.2 3.1 2 1 1 3 3 3 0 SEP domain Cag12 PF13117.6 EAX80559.1 - 0.21 12.2 8.9 0.47 11.0 0.5 4.2 3 1 1 4 4 4 0 Cag pathogenicity island protein Cag12 PTR PF12789.7 EAX80559.1 - 4 7.6 13.0 0.51 10.4 1.9 4.5 4 1 1 5 5 5 0 Phage tail repeat like HTH_22 PF13309.6 EAX80559.1 - 6.4 6.9 7.7 9.3 6.4 0.4 2.9 2 1 1 3 3 3 0 HTH domain DUF3839 PF12943.7 EAX80560.1 - 7.7e-147 487.2 15.3 1e-146 486.8 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX80560.1 - 0.0026 18.3 1.6 0.0082 16.7 0.3 2.5 3 0 0 3 3 3 1 T5orf172 domain Rx_N PF18052.1 EAX80560.1 - 0.021 15.1 0.6 0.17 12.2 0.1 2.6 3 1 0 3 3 3 0 Rx N-terminal domain Fez1 PF06818.15 EAX80560.1 - 0.084 13.3 1.8 0.14 12.6 0.3 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX80560.1 - 0.3 10.9 2.0 0.71 9.7 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80560.1 - 0.76 10.3 7.0 2.8 8.4 1.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80561.1 - 5.2e-121 402.6 11.1 6.3e-121 402.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80561.1 - 0.013 16.0 2.6 1.8 9.0 0.0 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX80562.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80562.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80562.1 - 4e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80562.1 - 0.00015 21.8 3.5 0.00035 20.6 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80562.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80562.1 - 0.0014 18.5 0.6 0.0027 17.5 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80562.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80562.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX80562.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80562.1 - 0.088 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX80562.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX80562.1 - 0.21 11.8 4.4 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GPS2_interact PF15784.5 EAX80563.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80563.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX80565.1 - 3.5e-35 119.8 26.3 2.9e-32 110.5 14.4 5.0 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX80565.1 - 0.042 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1947 PF09183.10 EAX80566.1 - 0.017 15.4 0.2 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) DUF4107 PF13389.6 EAX80567.1 - 8.2e-68 227.6 2.6 1.1e-67 227.3 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX80568.1 - 5.2e-09 36.4 0.0 9.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF960 PF06124.11 EAX80568.1 - 0.07 13.8 0.1 0.19 12.4 0.1 1.7 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) DUF4106 PF13388.6 EAX80570.1 - 8.2e-96 321.8 5.6 1.6e-95 320.8 5.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ribosomal_L18_c PF14204.6 EAX80570.1 - 0.06 14.3 3.2 3.3 8.7 2.3 3.0 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region DUF3839 PF12943.7 EAX80572.1 - 8.1e-159 526.4 13.4 9.5e-159 526.2 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80572.1 - 0.038 14.4 0.8 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80572.1 - 0.62 10.6 7.0 1.9 9.0 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX80573.1 - 1.4e-22 79.7 0.4 2.6e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 KilA-N domain EF-hand_7 PF13499.6 EAX80573.1 - 0.023 15.2 2.5 1.9 9.0 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair Tox-GHH PF15636.6 EAX80573.1 - 0.045 13.7 0.7 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX80573.1 - 0.24 10.8 0.7 1.1 8.7 0.2 2.2 2 2 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain FAS_N PF17828.1 EAX80575.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX80576.1 - 0.016 15.6 0.4 0.021 15.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF2400 PF09674.10 EAX80577.1 - 0.016 15.2 0.4 0.024 14.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) GPS2_interact PF15784.5 EAX80579.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX80580.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80580.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX80581.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80581.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX80582.1 - 1.1e-06 28.3 2.2 1.1e-06 28.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80582.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80582.1 - 5.7e-05 22.9 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80582.1 - 0.00013 22.0 3.1 0.00027 21.0 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80582.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80582.1 - 0.0013 18.6 0.6 0.005 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80582.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80582.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX80582.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80582.1 - 0.093 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80582.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX80582.1 - 0.26 11.7 3.2 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX80582.1 - 0.3 11.4 3.9 8.8 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX80583.1 - 4.6e-156 517.4 12.5 5.7e-156 517.1 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80583.1 - 0.1 12.9 0.4 2.1 8.7 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX80583.1 - 0.17 11.7 1.2 0.56 10.1 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80583.1 - 0.79 10.2 5.0 8.6 6.9 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX80584.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80584.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80584.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80584.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3781 PF12636.7 EAX80585.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Zn_peptidase PF04228.13 EAX80586.1 - 0.21 11.0 0.8 2.2 7.6 0.1 2.0 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase Amidase02_C PF12123.8 EAX80587.1 - 0.0062 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX80588.1 - 5.7e-155 513.8 12.6 7e-155 513.5 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80588.1 - 0.048 13.5 1.8 0.11 12.3 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80588.1 - 0.39 11.0 2.8 1.6 9.0 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX80588.1 - 0.76 10.3 7.4 2.1 8.9 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ly49 PF08391.10 EAX80589.1 - 0.29 11.5 2.0 0.34 11.3 2.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX80589.1 - 0.44 10.5 2.7 0.87 9.5 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX80590.1 - 4.5e-55 185.5 7.4 5e-55 185.4 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX80591.1 - 3.8e-153 507.9 16.2 4.7e-153 507.6 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80591.1 - 0.028 14.3 1.5 0.068 13.0 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Phage_lysozyme PF00959.19 EAX80591.1 - 0.036 14.5 0.3 0.6 10.6 0.1 2.3 2 0 0 2 2 2 0 Phage lysozyme Fez1 PF06818.15 EAX80591.1 - 0.054 13.9 1.9 0.27 11.7 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80591.1 - 0.076 13.5 6.3 0.66 10.5 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2547 PF10818.8 EAX80591.1 - 0.28 12.2 1.2 11 7.1 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Tup_N PF08581.10 EAX80591.1 - 1.5 9.2 7.2 17 5.8 0.1 4.1 4 2 1 5 5 5 0 Tup N-terminal GPS2_interact PF15784.5 EAX80592.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80592.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX80594.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80594.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80594.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80594.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF5623 PF18536.1 EAX80595.1 - 0.075 13.3 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX80595.1 - 0.18 11.7 5.6 0.15 12.0 2.9 2.1 2 1 0 2 2 2 0 Spo12 family DUF3839 PF12943.7 EAX80596.1 - 1.3e-153 509.4 16.1 1.6e-153 509.1 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80596.1 - 0.1 12.4 1.5 0.39 10.6 1.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80596.1 - 1.2 9.6 5.8 4.8 7.7 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX80597.1 - 3.3e-15 55.9 1.4 4.9e-15 55.3 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80597.1 - 0.0078 16.8 0.1 0.017 15.8 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX80598.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80598.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80598.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80598.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80598.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX80598.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Amidase02_C PF12123.8 EAX80599.1 - 0.0028 17.3 0.0 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX80600.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX80600.1 - 0.18 11.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) MULE PF10551.9 EAX80601.1 - 4.6e-10 39.8 1.8 4.8e-10 39.7 0.4 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX80601.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family PTR PF12789.7 EAX80603.1 - 5.4e-25 87.2 11.2 5.4e-25 87.2 11.2 4.5 4 1 0 4 4 4 1 Phage tail repeat like Pox_A32 PF04665.12 EAX80604.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80604.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80604.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80604.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX80605.1 - 9.6e-80 267.5 10.4 1.3e-79 267.1 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80605.1 - 0.11 13.0 0.6 0.18 12.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX80605.1 - 0.27 11.7 1.4 0.99 9.9 0.5 2.2 2 1 1 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX80605.1 - 0.42 11.0 2.3 2 8.8 1.1 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX80606.1 - 2.9e-148 491.9 16.8 3.5e-148 491.6 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80606.1 - 1.1 9.8 5.6 2.8 8.5 0.7 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80606.1 - 2 9.0 6.3 1.3 9.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5446 PF17522.2 EAX80607.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) AAA_22 PF13401.6 EAX80608.1 - 6.7e-05 23.2 0.1 0.00039 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80608.1 - 0.00013 22.0 3.8 0.00023 21.2 3.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80608.1 - 0.00039 20.2 0.0 0.00072 19.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80608.1 - 0.00066 19.6 1.2 0.0022 17.8 1.2 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80608.1 - 0.00089 19.0 0.4 0.076 12.7 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX80608.1 - 0.018 15.4 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80608.1 - 0.036 13.5 0.1 0.055 12.9 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX80608.1 - 0.073 12.7 0.9 0.12 12.0 0.4 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA PF00004.29 EAX80608.1 - 0.12 12.8 0.1 0.48 10.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrmK PF04816.12 EAX80608.1 - 0.13 11.8 3.0 0.24 10.9 3.0 1.5 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase AAA_25 PF13481.6 EAX80608.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX80608.1 - 0.34 11.2 5.2 5.5 7.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX80610.1 - 2.1e-59 199.6 7.9 2.3e-59 199.4 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80611.1 - 7.8e-06 26.3 2.9 4.5e-05 23.8 2.9 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80611.1 - 0.02 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX80611.1 - 0.06 13.3 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF1031 PF06275.11 EAX80612.1 - 0.023 14.9 0.0 0.035 14.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX80612.1 - 0.049 13.7 0.3 0.22 11.6 0.2 1.9 1 1 1 2 2 2 0 Annexin HARE-HTH PF05066.13 EAX80612.1 - 0.11 12.9 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DUF3839 PF12943.7 EAX80614.1 - 7.3e-77 258.1 12.1 9.3e-77 257.7 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80614.1 - 0.055 13.7 0.6 0.16 12.3 0.1 1.9 2 1 1 3 3 3 0 Rx N-terminal domain PRD PF00874.20 EAX80614.1 - 0.11 12.8 1.3 0.45 10.8 0.2 2.4 3 0 0 3 3 3 0 PRD domain NTP_transf_6 PF06042.11 EAX80614.1 - 0.13 12.1 1.5 0.48 10.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX80615.1 - 0.00014 22.4 0.3 0.00036 21.0 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX80616.1 - 0.093 12.7 12.7 0.1 12.6 12.7 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80616.1 - 1.9 8.9 5.0 2.3 8.7 5.0 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX80617.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80617.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF846 PF05832.12 EAX80618.1 - 0.034 14.2 0.1 0.067 13.2 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF4108 PF13390.6 EAX80621.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX80623.1 - 2.1e-72 242.6 3.2 2.7e-72 242.2 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80623.1 - 0.085 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta T5orf172 PF10544.9 EAX80624.1 - 3.8e-07 30.6 0.3 7.6e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Myb_DNA-bind_6 PF13921.6 EAX80625.1 - 1.6e-16 60.3 2.5 3.2e-10 40.1 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX80625.1 - 5.4e-16 58.5 0.9 4.3e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX80625.1 - 0.006 16.4 1.8 0.057 13.3 0.5 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX80625.1 - 0.11 12.8 5.2 0.78 10.2 3.4 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX80625.1 - 0.57 10.5 5.5 3.6 8.0 0.5 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HMG_box_2 PF09011.10 EAX80625.1 - 2.9 8.5 5.1 6.7 7.4 0.1 2.8 2 1 1 3 3 3 0 HMG-box domain DUF5365 PF17326.2 EAX80626.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) T5orf172 PF10544.9 EAX80627.1 - 3.5e-06 27.5 0.1 7.7e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80627.1 - 0.0034 17.2 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX80628.1 - 2e-79 266.5 10.2 2.6e-79 266.1 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX80629.1 - 6.6e-68 228.0 2.6 8.6e-68 227.6 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80631.1 - 2.9e-71 239.7 9.4 1.2e-70 237.8 9.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX80632.1 - 7.7e-07 29.6 0.1 1.9e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80632.1 - 0.0041 16.7 0.2 0.023 14.2 0.1 1.9 2 0 0 2 2 2 1 Legume lectin domain DUF4108 PF13390.6 EAX80633.1 - 0.006 16.5 9.3 0.0075 16.2 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phi-29_GP4 PF05464.11 EAX80633.1 - 0.083 13.2 1.1 0.16 12.3 0.2 1.9 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) KilA-N PF04383.13 EAX80634.1 - 7.1e-41 138.6 0.1 7.1e-41 138.6 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX80634.1 - 0.024 14.8 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX80634.1 - 0.12 11.0 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Meiosis_expr PF15163.6 EAX80635.1 - 0.0075 16.9 1.3 0.0099 16.5 0.6 1.6 2 0 0 2 2 2 1 Meiosis-expressed PHP_C PF13263.6 EAX80635.1 - 0.14 11.9 0.1 0.55 10.0 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX80635.1 - 1.6 8.7 11.0 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family DUF3839 PF12943.7 EAX80636.1 - 6.5e-158 523.5 13.1 8e-158 523.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX80636.1 - 0.085 13.3 0.3 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX80636.1 - 0.41 11.1 7.2 2.3 8.8 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX80636.1 - 5.2 7.4 7.5 14 6.1 0.1 3.8 3 2 1 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX80637.1 - 6.6e-08 32.3 1.3 7.8e-08 32.1 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80637.1 - 0.0039 16.9 0.1 0.0042 16.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80637.1 - 0.039 13.7 0.1 0.091 12.5 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80637.1 - 0.069 13.1 0.4 0.63 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3781 PF12636.7 EAX80638.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX80639.1 - 1.1e-72 243.4 4.1 1.6e-72 242.9 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80640.1 - 2.4e-153 508.5 13.1 2.8e-153 508.3 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80640.1 - 0.085 13.3 6.5 1.7 9.1 0.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX80640.1 - 0.1 13.1 0.3 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4108 PF13390.6 EAX80642.1 - 3.9e-63 211.6 5.7 4.4e-63 211.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX80643.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX80643.1 - 0.92 9.4 5.3 1.8 8.5 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S49_N PF08496.10 EAX80643.1 - 2.8 8.0 6.5 3 7.9 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PapD_N PF00345.20 EAX80645.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX80646.1 - 9e-09 34.7 2.6 1.5e-08 34.0 1.4 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX80646.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX80646.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Gly_rich PF12810.7 EAX80647.1 - 3.3e-50 171.3 33.3 4.1e-50 171.0 33.3 1.0 1 0 0 1 1 1 1 Glycine rich protein KilA-N PF04383.13 EAX80648.1 - 9.6e-23 80.2 0.3 1.8e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX80648.1 - 0.068 13.2 0.8 0.2 11.6 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NB-ARC PF00931.22 EAX80648.1 - 0.072 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2313 PF10076.9 EAX80648.1 - 0.076 12.9 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Chal_sti_synt_N PF00195.19 EAX80648.1 - 0.24 10.8 0.5 1.1 8.7 0.2 2.1 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX80649.1 - 3.7e-158 524.3 13.6 4.6e-158 524.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80649.1 - 4.3 7.8 8.6 2.4 8.7 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX80650.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80650.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX80650.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80650.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX80651.1 - 1e-33 115.5 0.4 2.4e-33 114.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80651.1 - 0.021 15.5 0.0 0.054 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF4107 PF13389.6 EAX80653.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX80653.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX80654.1 - 2e-37 127.0 29.3 7.2e-31 106.0 10.2 4.2 5 1 0 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX80654.1 - 0.081 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX80655.1 - 0.017 15.6 0.4 0.032 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX80656.1 - 4.8e-24 85.1 3.3 7.7e-24 84.5 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX80656.1 - 0.04 14.2 0.9 0.081 13.2 0.9 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 ZapB PF06005.12 EAX80656.1 - 0.044 14.2 0.4 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PRD PF00874.20 EAX80656.1 - 0.047 14.0 0.3 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain T5orf172 PF10544.9 EAX80657.1 - 9.6e-06 26.1 0.2 2.6e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80657.1 - 0.00014 21.4 0.2 0.016 14.7 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX80657.1 - 0.013 15.3 0.1 0.094 12.6 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX80658.1 - 3.2e-155 514.7 12.8 3.8e-155 514.4 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80658.1 - 0.065 13.7 2.5 0.23 11.9 0.5 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX80658.1 - 0.15 11.9 1.6 0.5 10.2 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80658.1 - 0.84 10.1 6.3 4 7.9 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAX80659.1 - 5.5e-64 216.1 0.0 6.3e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX80659.1 - 8.9e-34 116.9 0.0 1.3e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX80659.1 - 6.1e-07 29.0 0.1 0.022 14.1 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 EAX80659.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Imm7 PF15585.6 EAX80659.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 DUF3839 PF12943.7 EAX80660.1 - 1.2e-79 267.2 9.8 1.6e-79 266.8 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80660.1 - 0.052 14.1 0.4 0.083 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX80661.1 - 4e-49 164.5 28.8 9.2e-32 108.9 13.4 4.2 3 2 2 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX80661.1 - 0.029 14.1 0.9 0.057 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX80662.1 - 0.018 15.5 0.5 0.036 14.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX80663.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX80663.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase GPS2_interact PF15784.5 EAX80667.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80667.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80668.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80668.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX80670.1 - 1.9e-73 245.9 4.2 2.3e-73 245.7 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80670.1 - 0.098 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX80670.1 - 0.15 10.4 0.9 0.22 9.9 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX80672.1 - 2.3e-156 518.4 13.1 2.9e-156 518.1 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80672.1 - 0.2 11.5 1.7 0.62 9.9 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80672.1 - 0.54 10.8 5.6 5.2 7.6 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80672.1 - 0.57 10.7 5.3 0.74 10.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) MULE PF10551.9 EAX80673.1 - 2.8e-06 27.6 0.0 4.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF3013 PF11217.8 EAX80673.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) DDR PF08841.10 EAX80674.1 - 0.066 12.2 0.1 0.069 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX80674.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TMP PF05017.14 EAX80675.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX80677.1 - 7.7e-52 173.2 33.0 8.2e-35 118.7 16.8 4.6 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX80677.1 - 0.017 14.9 1.7 0.021 14.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PapD_N PF00345.20 EAX80678.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX80678.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX80679.1 - 6.3e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX80679.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX80679.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4107 PF13389.6 EAX80680.1 - 4.4e-72 241.5 3.7 5.7e-72 241.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80680.1 - 0.0041 17.5 0.1 0.0096 16.3 0.1 1.6 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX80682.1 - 4.1e-07 29.7 1.4 6.8e-07 29.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80683.1 - 3.2e-132 439.4 9.9 3.7e-132 439.1 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80683.1 - 0.095 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase DNA_pol_B_2 PF03175.13 EAX80684.1 - 8.1e-31 107.4 12.4 3.6e-30 105.3 12.4 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX80685.1 - 2.1e-157 521.8 11.4 2.5e-157 521.5 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80685.1 - 0.6 10.7 5.2 0.24 12.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80685.1 - 1 9.9 4.3 5.2 7.6 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX80685.1 - 1.6 9.1 5.9 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Tup N-terminal YmaF PF12788.7 EAX80688.1 - 0.18 12.4 1.6 6.9 7.3 0.1 2.1 1 1 0 1 1 1 0 YmaF family DUF3839 PF12943.7 EAX80689.1 - 4.9e-127 422.4 4.5 5.5e-127 422.2 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX80690.1 - 1.9e-36 124.3 0.8 3.3e-36 123.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80690.1 - 0.0037 17.9 0.4 0.0096 16.5 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX80691.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80691.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX80691.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX80691.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX80691.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX80691.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) AAA_22 PF13401.6 EAX80693.1 - 7.7e-05 23.0 0.1 0.0004 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80693.1 - 8.5e-05 22.6 2.7 0.00016 21.7 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80693.1 - 0.00058 19.7 0.0 0.00085 19.1 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80693.1 - 0.0009 19.1 0.6 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80693.1 - 0.0016 18.2 0.4 0.36 10.5 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX80693.1 - 0.01 16.2 0.0 0.014 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80693.1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX80693.1 - 0.09 13.2 0.1 0.49 10.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX80693.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX80693.1 - 0.42 10.9 4.8 7 7.0 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX80695.1 - 1.5e-46 158.5 2.0 2.1e-46 158.1 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX80697.1 - 7.3e-07 28.9 2.9 7.3e-07 28.9 2.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX80697.1 - 2.3e-05 24.2 0.2 0.29 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX80697.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80697.1 - 0.00015 21.9 3.2 0.00032 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80697.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80697.1 - 0.0011 18.9 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80697.1 - 0.002 17.8 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80697.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX80697.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX80697.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80697.1 - 0.084 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80697.1 - 0.094 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80697.1 - 0.21 11.8 3.8 6.7 7.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) IstB_IS21 PF01695.17 EAX80698.1 - 2.1e-05 24.3 0.4 0.23 11.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX80698.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX80698.1 - 6.5e-05 22.5 2.1 6.5e-05 22.5 2.1 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX80698.1 - 0.00031 20.8 4.5 0.00057 19.9 4.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80698.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80698.1 - 0.0029 17.4 1.7 0.0079 16.0 0.9 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80698.1 - 0.0038 16.9 2.7 0.014 15.1 0.2 2.6 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80698.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX80698.1 - 0.063 13.3 0.7 0.99 9.5 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX80698.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80698.1 - 0.075 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80698.1 - 0.088 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80698.1 - 0.61 10.4 5.0 8.4 6.7 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX80698.1 - 3.2 8.5 10.7 0.28 11.9 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAX80699.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX80700.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Mem_trans PF03547.18 EAX80701.1 - 4.5e-20 71.4 2.8 5.4e-20 71.1 2.8 1.0 1 0 0 1 1 1 1 Membrane transport protein DNA_pol_B_2 PF03175.13 EAX80702.1 - 1.8e-10 40.3 3.3 1e-09 37.8 3.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX80702.1 - 0.054 13.5 0.0 0.55 10.3 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX80702.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF5106 PF17127.4 EAX80702.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) DNA_pol_B_2 PF03175.13 EAX80703.1 - 1.9e-15 56.7 2.1 3.2e-15 56.0 2.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX80705.1 - 7.8e-129 428.3 7.4 8.9e-129 428.1 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX80705.1 - 0.037 14.2 0.1 0.091 13.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF29 KELK PF15796.5 EAX80705.1 - 0.28 11.7 2.7 0.81 10.2 0.6 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80706.1 - 3.2e-40 138.1 4.4 4.3e-40 137.7 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80706.1 - 0.083 13.5 0.3 0.096 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ER PF01133.17 EAX80709.1 - 0.0037 17.3 3.8 0.0039 17.2 0.9 2.1 1 1 1 2 2 2 1 Enhancer of rudimentary DUF2458 PF10454.9 EAX80709.1 - 0.0075 15.9 5.3 0.0099 15.5 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) ZapB PF06005.12 EAX80709.1 - 0.031 14.7 12.4 0.22 12.0 0.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB HAUS-augmin3 PF14932.6 EAX80709.1 - 0.044 13.4 6.7 0.11 12.1 6.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF848 PF05852.11 EAX80709.1 - 0.08 13.1 7.7 0.069 13.3 6.2 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) MitMem_reg PF13012.6 EAX80709.1 - 0.4 11.1 3.9 0.98 9.9 3.9 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Baculo_PEP_C PF04513.12 EAX80709.1 - 0.5 10.4 8.1 1.1 9.3 8.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 EAX80709.1 - 0.63 10.4 15.5 12 6.3 15.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 EAX80709.1 - 1 8.5 8.6 1.8 7.8 8.6 1.5 1 1 0 1 1 1 0 TMPIT-like protein PEP-utilisers_N PF05524.13 EAX80709.1 - 1.1 9.5 4.4 9 6.5 0.8 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1664 PF07889.12 EAX80709.1 - 1.7 8.7 7.1 2.6 8.1 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EAX80709.1 - 2 7.2 7.6 2.2 7.1 7.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2179 PF10035.9 EAX80709.1 - 3 7.6 6.0 18 5.1 0.1 3.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2179) ING PF12998.7 EAX80709.1 - 5.8 7.6 11.6 3.9 8.1 7.2 2.4 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding S_layer_C PF05124.12 EAX80710.1 - 0.058 13.4 0.3 0.069 13.1 0.3 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF3839 PF12943.7 EAX80711.1 - 1.2e-57 195.2 4.1 1.3e-57 195.0 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80711.1 - 0.018 14.5 0.3 0.021 14.4 0.3 1.0 1 0 0 1 1 1 0 Z1 domain DUF3839 PF12943.7 EAX80714.1 - 5.8e-133 441.8 13.3 1.8e-132 440.2 13.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80714.1 - 0.088 13.3 3.1 0.13 12.6 0.7 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80714.1 - 0.2 12.1 9.0 0.55 10.7 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX80716.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80716.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX80718.1 - 0.053 14.0 0.5 0.065 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX80719.1 - 0.093 12.7 6.6 0.14 12.1 6.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80719.1 - 2.6 8.5 5.1 3.6 8.0 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TsaE PF02367.17 EAX80720.1 - 0.051 13.6 0.9 50 3.9 0.0 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mo-nitro_C PF06967.11 EAX80722.1 - 4.5 7.3 21.1 6.1 6.9 1.8 3.3 1 1 2 3 3 3 0 Mo-dependent nitrogenase C-terminus DUF3839 PF12943.7 EAX80723.1 - 6.1e-97 323.8 7.6 7.5e-97 323.5 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80725.1 - 1.9e-154 512.1 14.5 2.3e-154 511.9 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80725.1 - 0.098 12.9 3.7 0.13 12.5 0.1 2.9 2 2 0 2 2 2 0 Rx N-terminal domain Fez1 PF06818.15 EAX80725.1 - 0.12 12.8 2.8 0.38 11.2 0.5 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX80725.1 - 0.21 11.4 2.0 0.5 10.2 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80725.1 - 0.38 11.3 7.4 2 9.0 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX80725.1 - 4.5 7.7 6.9 1.3 9.3 0.1 3.2 4 1 1 5 5 5 0 PRD domain DUF3839 PF12943.7 EAX80728.1 - 1.8e-93 312.4 7.9 2.1e-93 312.2 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80729.1 - 2.8e-156 518.1 12.0 3.4e-156 517.8 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80729.1 - 0.058 13.8 1.8 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80729.1 - 0.55 10.7 7.6 2 8.9 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX80730.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80730.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX80731.1 - 5.1e-22 77.7 20.6 4.2e-16 58.7 1.7 4.7 6 0 0 6 6 6 2 Phage tail repeat like T5orf172 PF10544.9 EAX80732.1 - 1.3e-06 28.9 0.2 2.5e-06 28.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain T5orf172 PF10544.9 EAX80734.1 - 7.5e-07 29.6 0.3 2.1e-06 28.2 0.3 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80734.1 - 0.018 14.6 1.1 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX80734.1 - 0.038 13.8 1.2 0.075 12.9 0.5 2.0 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX80735.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 KilA-N domain Baculo_ME53 PF06061.11 EAX80735.1 - 0.042 13.1 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX80735.1 - 0.061 12.8 0.4 0.084 12.4 0.4 1.2 1 0 0 1 1 1 0 Legume lectin domain T5orf172 PF10544.9 EAX80735.1 - 0.07 13.7 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 T5orf172 domain DUF3839 PF12943.7 EAX80736.1 - 2.4e-78 262.9 10.2 3.2e-78 262.6 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) UCH PF00443.29 EAX80737.1 - 1.2e-09 38.1 0.2 1.9e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX80737.1 - 0.00071 19.3 0.2 0.00097 18.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX80737.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase VirK PF06903.12 EAX80739.1 - 0.032 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 VirK protein DUF4108 PF13390.6 EAX80742.1 - 1.3e-62 209.9 5.9 1.5e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RFX_DNA_binding PF02257.15 EAX80743.1 - 0.00021 21.9 0.2 0.00031 21.3 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX80743.1 - 0.00066 20.1 1.7 0.0013 19.2 1.7 1.5 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX80743.1 - 0.056 13.4 1.1 0.093 12.7 0.1 1.9 2 1 0 2 2 2 0 CDC6, C terminal winged helix domain DUF3839 PF12943.7 EAX80744.1 - 2.1e-133 443.2 13.4 6.3e-133 441.7 13.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX80744.1 - 0.11 12.9 1.1 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX80744.1 - 0.17 12.4 8.4 0.97 9.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80745.1 - 4.5e-158 524.0 15.9 5.5e-158 523.7 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80745.1 - 0.074 12.9 1.9 0.16 11.8 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX80745.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.0 5 0 0 5 5 5 0 PRD domain KELK PF15796.5 EAX80745.1 - 2.5 8.6 8.0 2.1 8.8 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1031 PF06275.11 EAX80746.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) DUF2791 PF10923.8 EAX80746.1 - 0.031 13.1 0.0 0.031 13.1 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Annexin PF00191.20 EAX80746.1 - 0.066 13.3 0.7 0.29 11.3 0.2 2.1 2 1 1 3 3 3 0 Annexin HARE-HTH PF05066.13 EAX80746.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain T5orf172 PF10544.9 EAX80747.1 - 7.9e-07 29.6 0.2 1.9e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80747.1 - 0.0073 16.1 0.6 0.038 13.8 0.1 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX80747.1 - 0.025 14.1 1.1 0.22 11.0 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX80748.1 - 1.5e-155 515.8 14.3 1.8e-155 515.4 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80748.1 - 0.11 13.0 4.0 2.3 8.8 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX80748.1 - 0.31 11.4 1.5 1.1 9.6 0.4 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX80748.1 - 0.9 10.1 4.4 1.2 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX80750.1 - 4.5e-37 126.3 1.4 6e-37 125.9 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX80750.1 - 0.046 13.7 7.4 0.085 12.8 7.4 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF4106 PF13388.6 EAX80752.1 - 2.4e-276 916.5 43.0 2.6e-152 507.9 14.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80752.1 - 0.0016 18.7 0.2 0.06 13.6 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated Metallophos PF00149.28 EAX80754.1 - 1.9e-22 80.8 0.2 3e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3839 PF12943.7 EAX80755.1 - 5.6e-154 510.6 14.8 6.6e-154 510.3 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80755.1 - 0.0046 17.2 0.7 0.32 11.3 0.1 3.0 3 1 0 3 3 3 1 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX80755.1 - 0.06 13.2 1.2 0.19 11.6 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80755.1 - 0.13 12.7 5.9 1.5 9.3 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX80755.1 - 1.4 9.6 4.6 1.9 9.2 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF4108 PF13390.6 EAX80756.1 - 8.1e-61 204.1 7.5 9e-61 204.0 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX80758.1 - 2.9e-152 505.0 14.8 3.7e-152 504.6 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80758.1 - 0.036 14.5 1.9 1.8 9.1 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX80758.1 - 0.096 12.5 0.8 0.32 10.9 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX80758.1 - 0.35 11.2 3.8 13 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal DUF4107 PF13389.6 EAX80759.1 - 5.2e-30 104.7 4.5 4.7e-28 98.4 4.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX80760.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Peptidase_S64 PF08192.11 EAX80761.1 - 0.0062 15.1 0.0 0.0063 15.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 Pox_A32 PF04665.12 EAX80762.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80762.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80762.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80762.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80762.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80762.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80762.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX80763.1 - 8.6e-42 141.5 0.3 2.1e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80763.1 - 0.007 17.0 0.1 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family GPS2_interact PF15784.5 EAX80764.1 - 0.1 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4106 PF13388.6 EAX80765.1 - 1e-95 321.5 11.0 1e-95 321.5 11.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80765.1 - 0.0025 18.1 0.2 0.19 12.1 0.1 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAX80765.1 - 0.056 14.0 0.5 0.17 12.5 0.5 1.8 1 0 0 1 1 1 0 Viral protein VP4 subunit WYL_3 PF18488.1 EAX80765.1 - 2.5 8.5 11.4 4.8 7.6 0.7 3.9 4 0 0 4 4 4 0 WYL domain DUF3839 PF12943.7 EAX80766.1 - 4.3e-88 294.8 6.5 4.9e-88 294.7 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) VirE PF05272.11 EAX80767.1 - 1.2e-05 25.2 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX80767.1 - 0.028 13.5 1.2 0.095 11.8 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX80768.1 - 8.6e-157 519.8 14.1 1.1e-156 519.5 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80768.1 - 0.11 12.9 2.5 0.14 12.5 0.4 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80768.1 - 0.86 10.1 7.6 2.3 8.8 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF668 PF05003.12 EAX80770.1 - 0.22 12.0 1.9 0.48 10.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF668) COPIIcoated_ERV PF07970.12 EAX80770.1 - 0.87 9.4 4.0 2.1 8.1 4.0 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum vesicle transporter Gly-zipper_Omp PF13488.6 EAX80772.1 - 0.0072 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX80772.1 - 0.12 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX80772.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX80772.1 - 1.4 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Aa_trans PF01490.18 EAX80773.1 - 2.4e-16 59.5 18.9 3.1e-16 59.1 18.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4108 PF13390.6 EAX80775.1 - 3.8e-59 198.7 9.1 4.2e-59 198.6 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX80775.1 - 0.1 12.9 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide AAA_22 PF13401.6 EAX80777.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80777.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80777.1 - 0.0043 17.4 0.0 0.0061 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX80777.1 - 0.0052 16.8 0.0 0.0063 16.5 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX80777.1 - 0.023 14.1 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX80777.1 - 0.057 13.0 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX80777.1 - 0.075 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX80777.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EAX80779.1 - 1.9e-05 24.7 0.9 3.6e-05 23.8 0.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80779.1 - 0.00031 20.6 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX80779.1 - 0.00041 20.6 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX80779.1 - 0.0013 18.6 0.1 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX80779.1 - 0.0068 16.8 0.0 0.0085 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80779.1 - 0.037 13.5 0.0 0.046 13.2 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX80779.1 - 0.061 13.0 0.3 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX80779.1 - 0.098 12.4 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX80779.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX80779.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX80779.1 - 0.43 11.0 2.7 0.4 11.1 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX80781.1 - 2.2e-62 209.2 6.2 2.5e-62 209.1 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3447 PF11929.8 EAX80782.1 - 5.2e-31 106.4 1.7 1.2e-30 105.3 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Aminotran_3 PF00202.21 EAX80783.1 - 2.7e-100 335.9 0.0 3.1e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CAF1-p150_C2 PF15539.6 EAX80783.1 - 0.19 11.2 1.2 0.29 10.5 1.2 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term KilA-N PF04383.13 EAX80784.1 - 3.8e-10 39.6 0.9 5.5e-10 39.1 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF2313 PF10076.9 EAX80784.1 - 0.043 13.7 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) PcfK PF14058.6 EAX80785.1 - 0.029 14.7 7.4 0.039 14.2 7.4 1.3 1 1 0 1 1 1 0 PcfK-like protein Trypan_PARP PF05887.11 EAX80785.1 - 0.24 11.4 5.2 0.31 11.0 5.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX80786.1 - 4.3e-63 211.5 5.7 4.8e-63 211.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX80787.1 - 0.00022 21.7 2.5 0.0014 19.0 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX80787.1 - 0.036 13.1 1.2 0.049 12.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF5106 PF17127.4 EAX80788.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX80790.1 - 4.5e-55 186.7 2.8 5e-55 186.6 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX80790.1 - 0.047 14.3 0.8 0.18 12.5 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DDE_1 PF03184.19 EAX80791.1 - 5.4e-13 49.0 0.3 9.8e-13 48.1 0.1 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3781 PF12636.7 EAX80792.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) ACP_PD PF04336.12 EAX80794.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Trypan_PARP PF05887.11 EAX80795.1 - 0.025 14.6 8.2 0.031 14.3 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80795.1 - 7.8 7.0 6.1 9.6 6.6 6.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX80796.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DNA_pol_B_2 PF03175.13 EAX80797.1 - 5.6e-12 45.3 0.2 1e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX80799.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX80800.1 - 8.9e-81 270.9 3.4 1e-80 270.7 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80800.1 - 0.025 14.1 0.2 0.028 13.9 0.2 1.1 1 0 0 1 1 1 0 Z1 domain PSP PF04046.16 EAX80801.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX80802.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX80804.1 - 1.3e-117 391.5 8.8 1.5e-117 391.3 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trns_repr_metal PF02583.17 EAX80804.1 - 0.02 15.3 0.2 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor KilA-N PF04383.13 EAX80805.1 - 6.8e-23 80.7 0.3 1.3e-22 79.8 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX80805.1 - 0.046 13.7 1.0 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX80806.1 - 2.7e-157 521.4 11.5 3.2e-157 521.2 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80806.1 - 0.092 13.2 5.0 2 9.0 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX80807.1 - 0.075 13.0 11.1 0.12 12.4 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX80808.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80808.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX80810.1 - 1.6e-72 243.0 3.9 2.1e-72 242.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2939 PF11159.8 EAX80812.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX80812.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAX80813.1 - 0.048 13.6 1.0 0.072 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX80816.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX80817.1 - 0.039 14.4 0.4 0.054 13.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX80817.1 - 1.5 9.5 4.8 2.6 8.7 4.8 1.5 1 1 0 1 1 1 0 Homeodomain-like domain Pox_A32 PF04665.12 EAX80820.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80820.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80820.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80820.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80820.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80820.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80820.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80820.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX80820.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX80820.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80820.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX80820.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80820.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX80821.1 - 9.3e-148 490.2 14.0 1.2e-147 489.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80821.1 - 0.093 13.0 0.6 2.5 8.4 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX80821.1 - 0.3 11.6 7.1 2.2 8.8 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX80821.1 - 5.1 7.5 7.8 14 6.1 0.1 4.0 4 2 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX80821.1 - 7.4 7.1 7.4 0.68 10.5 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX80822.1 - 1.7e-11 43.9 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX80822.1 - 0.14 11.5 0.6 0.3 10.5 0.6 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX80823.1 - 2.1e-158 525.1 13.2 2.6e-158 524.8 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80823.1 - 0.27 11.1 1.7 1.3 8.8 1.7 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX80823.1 - 1.6 9.3 7.9 1.3 9.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Microtub_bd PF16796.5 EAX80824.1 - 0.05 13.5 0.7 0.11 12.4 0.7 1.7 1 1 1 2 2 2 0 Microtubule binding DUF4108 PF13390.6 EAX80825.1 - 2e-61 206.1 5.2 2.2e-61 206.0 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX80825.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Methyltr_RsmB-F PF01189.17 EAX80826.1 - 0.064 12.9 0.4 1.3 8.7 0.2 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F ResIII PF04851.15 EAX80827.1 - 8.7e-05 22.6 3.2 0.00016 21.7 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX80827.1 - 8.8e-05 22.8 0.0 0.00045 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX80827.1 - 0.0004 20.2 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80827.1 - 0.001 18.9 1.2 0.0035 17.2 1.2 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80827.1 - 0.0018 18.0 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX80827.1 - 0.0093 16.3 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX80827.1 - 0.048 13.1 0.1 0.076 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX80827.1 - 0.051 13.3 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX80827.1 - 0.086 13.3 0.1 0.38 11.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX80827.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX80827.1 - 0.17 12.2 5.0 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX80828.1 - 2.8e-149 495.2 11.7 3.3e-149 495.0 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80828.1 - 0.1 12.4 0.4 0.29 11.0 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase DUF1731 PF08338.11 EAX80830.1 - 0.11 12.3 0.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) VirE PF05272.11 EAX80831.1 - 3.5e-05 23.6 0.1 6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Virulence-associated protein E Pox_D5 PF03288.16 EAX80831.1 - 0.00018 21.9 3.2 0.0014 19.1 3.2 2.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RNA_helicase PF00910.22 EAX80831.1 - 0.055 13.9 0.3 0.19 12.1 0.1 2.0 1 1 0 2 2 2 0 RNA helicase DUF4108 PF13390.6 EAX80832.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX80833.1 - 0.56 10.1 2.7 1.2 9.1 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX80834.1 - 1.5e-32 111.4 28.9 3.4e-31 107.1 12.4 7.1 5 2 2 7 7 7 3 Phage tail repeat like DUF4116 PF13475.6 EAX80834.1 - 0.03 14.1 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DDR PF08841.10 EAX80835.1 - 0.088 11.8 0.2 0.091 11.7 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80836.1 - 0.033 14.2 7.8 0.043 13.8 7.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80836.1 - 1.9 8.9 4.7 2.4 8.6 4.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin T5orf172 PF10544.9 EAX80837.1 - 6e-07 30.0 0.2 1.2e-06 29.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX80839.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80839.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX80840.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX80842.1 - 2.4e-66 222.9 13.1 2.6e-64 216.3 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80842.1 - 0.097 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta HTH_Tnp_4 PF13613.6 EAX80843.1 - 1.7e-05 24.4 0.2 0.00032 20.4 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease PadR PF03551.14 EAX80845.1 - 0.037 14.0 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family CDC45 PF02724.14 EAX80848.1 - 0.61 8.3 18.9 1 7.6 18.9 1.3 1 0 0 1 1 1 0 CDC45-like protein MAP7 PF05672.11 EAX80848.1 - 9.4 5.9 62.2 0.35 10.5 52.6 2.7 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF3839 PF12943.7 EAX80850.1 - 1.6e-156 518.9 14.1 2e-156 518.6 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80850.1 - 0.092 13.2 1.8 0.37 11.2 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80850.1 - 0.23 11.9 4.9 2 8.9 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX80850.1 - 0.49 10.7 2.9 2.2 8.6 0.1 3.1 2 2 1 3 3 3 0 Rx N-terminal domain Tup_N PF08581.10 EAX80850.1 - 0.54 10.6 4.4 11 6.4 0.1 3.9 4 1 0 4 4 4 0 Tup N-terminal DUF4107 PF13389.6 EAX80852.1 - 7.3e-73 244.1 3.0 9.5e-73 243.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDR PF08841.10 EAX80853.1 - 0.083 11.9 0.2 0.084 11.8 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX80853.1 - 0.28 11.7 3.0 0.33 11.4 3.0 1.3 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX80854.1 - 0.048 13.6 10.5 0.063 13.3 10.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX80855.1 - 5.6e-07 29.4 0.3 1.3e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Pkinase PF00069.25 EAX80856.1 - 3.8e-66 223.2 0.0 5.8e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX80856.1 - 1.6e-36 126.0 0.0 6.8e-36 123.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX80856.1 - 6.4e-09 35.5 0.1 2.2e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EAX80856.1 - 9.7e-07 28.9 0.1 0.023 14.6 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 EAX80856.1 - 2.9e-06 27.1 0.6 0.024 14.3 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX80856.1 - 0.00022 20.1 0.7 0.00043 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EAX80856.1 - 0.00092 18.9 0.2 0.0061 16.2 0.2 2.1 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAX80856.1 - 0.0032 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX80856.1 - 0.069 12.2 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3839 PF12943.7 EAX80857.1 - 1.7e-127 423.9 5.6 2e-127 423.7 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX80859.1 - 2.9e-58 197.2 4.0 3.4e-58 197.0 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX80859.1 - 0.041 13.4 0.1 0.046 13.2 0.1 1.0 1 0 0 1 1 1 0 Z1 domain Glu-tRNAGln PF02686.15 EAX80859.1 - 0.1 12.9 1.3 0.21 11.9 1.3 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF5398 PF17376.2 EAX80859.1 - 0.18 12.4 2.2 1.1 9.9 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) NAD_binding_8 PF13450.6 EAX80860.1 - 0.068 13.4 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3839 PF12943.7 EAX80862.1 - 2e-156 518.6 13.7 2.5e-156 518.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX80862.1 - 0.41 11.1 7.3 2.1 8.9 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80862.1 - 0.9 10.1 6.2 0.38 11.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX80863.1 - 6e-149 494.1 15.3 7.3e-149 493.8 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX80863.1 - 0.031 14.5 0.7 0.064 13.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX80863.1 - 0.04 14.4 0.9 0.073 13.5 0.2 1.7 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80863.1 - 0.37 11.3 6.8 1.3 9.5 0.5 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX80864.1 - 6.1e-06 26.7 0.1 1.4e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80864.1 - 0.003 17.4 1.9 0.016 15.0 0.8 2.5 2 1 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX80865.1 - 4.5e-40 136.0 0.6 9.5e-40 134.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80865.1 - 0.014 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX80865.1 - 0.081 12.2 0.1 0.27 10.4 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase Pkinase PF00069.25 EAX80866.1 - 2.2e-20 73.1 3.3 3.6e-20 72.4 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX80866.1 - 4.6e-09 36.0 0.0 9.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3839 PF12943.7 EAX80867.1 - 4.7e-80 268.5 8.8 6.1e-80 268.2 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80867.1 - 0.041 14.4 0.4 0.07 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX80868.1 - 7.1e-23 80.6 0.3 1.3e-22 79.7 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX80868.1 - 0.15 11.4 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain KilA-N PF04383.13 EAX80869.1 - 1.9e-45 153.3 0.5 3.8e-45 152.3 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80869.1 - 0.0049 17.5 0.2 0.017 15.7 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX80869.1 - 0.95 9.5 3.7 7.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF3839 PF12943.7 EAX80870.1 - 2.3e-25 89.5 4.0 3.2e-25 89.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX80870.1 - 0.049 13.9 0.6 0.19 12.0 0.1 2.0 1 1 1 2 2 2 0 PRD domain DUF5077 PF16871.5 EAX80871.1 - 0.077 12.9 4.4 0.087 12.7 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) EpuA PF11772.8 EAX80872.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Phage_fiber PF03335.13 EAX80872.1 - 1.1 9.7 22.2 0.95 9.8 3.3 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat T5orf172 PF10544.9 EAX80873.1 - 1.4e-05 25.6 0.3 5.2e-05 23.7 0.1 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX80874.1 - 1.2e-25 89.6 0.1 1.2e-25 89.6 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80874.1 - 0.0034 17.5 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX80875.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80875.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX80875.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80875.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80875.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80875.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80875.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Trypan_PARP PF05887.11 EAX80876.1 - 0.074 13.0 6.5 0.11 12.4 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX80877.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80877.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX80879.1 - 1.7e-65 220.1 13.4 1.9e-63 213.4 13.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80879.1 - 0.097 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Gln-synt_C-ter PF18318.1 EAX80880.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain GPS2_interact PF15784.5 EAX80881.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80881.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80882.1 - 0.075 13.0 6.9 0.098 12.6 6.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80882.1 - 1.8 9.0 5.4 2.3 8.7 5.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX80883.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80883.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Collagen_bind_2 PF12904.7 EAX80884.1 - 0.089 12.8 0.0 2.5 8.1 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase MinE PF03776.14 EAX80885.1 - 0.13 12.3 1.7 23 5.1 0.1 3.1 1 1 3 4 4 4 0 Septum formation topological specificity factor MinE ECF_trnsprt PF12822.7 EAX80885.1 - 0.52 10.4 9.6 0.67 10.0 9.6 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component BIRC6 PF12356.8 EAX80885.1 - 1.5 8.2 7.0 5.2 6.5 0.8 2.0 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Pox_A14 PF05767.12 EAX80885.1 - 2.9 8.1 12.8 11 6.3 0.5 3.4 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 GPS2_interact PF15784.5 EAX80887.1 - 0.032 14.7 0.4 0.041 14.3 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX80888.1 - 0.017 15.1 9.6 0.019 14.9 9.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80888.1 - 6.9 7.1 8.0 8.5 6.8 8.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_D5 PF03288.16 EAX80889.1 - 7.6e-05 23.1 2.7 0.00036 21.0 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80889.1 - 0.032 14.9 0.1 0.066 13.8 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX80889.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX80889.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX80890.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX80891.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX80892.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX80893.1 - 0.0043 16.7 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX80894.1 - 4.3e-07 29.7 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX80895.1 - 1.4e-155 515.8 12.2 1.8e-155 515.5 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80895.1 - 0.15 11.9 1.0 0.53 10.1 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX80896.1 - 1.3e-31 108.5 37.1 8.6e-25 86.6 6.1 6.4 5 2 1 6 6 6 3 Phage tail repeat like DUF4116 PF13475.6 EAX80896.1 - 0.12 12.2 0.1 0.46 10.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX80896.1 - 0.21 12.1 2.9 0.3 11.6 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3417) SAS4 PF15460.6 EAX80896.1 - 3 8.0 10.0 18 5.5 4.3 2.9 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF1493 PF07377.12 EAX80897.1 - 0.095 13.2 0.6 0.16 12.4 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) Amidase02_C PF12123.8 EAX80898.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX80899.1 - 1.7e-156 518.9 11.8 1.9e-156 518.7 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80899.1 - 0.0085 16.6 1.0 0.071 13.5 0.1 2.1 2 0 0 2 2 2 1 Fez1 KELK PF15796.5 EAX80899.1 - 0.33 11.4 6.5 1.4 9.5 0.4 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80899.1 - 0.96 10.0 4.2 1.2 9.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX80900.1 - 5.2e-07 29.4 2.3 5.2e-07 29.4 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX80900.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80900.1 - 5.4e-05 23.0 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80900.1 - 0.00014 21.9 3.4 0.00031 20.8 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80900.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX80900.1 - 0.0015 18.4 0.7 0.0029 17.4 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80900.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80900.1 - 0.011 16.0 0.0 0.023 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX80900.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX80900.1 - 0.089 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX80900.1 - 0.09 13.2 0.1 0.76 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX80900.1 - 0.22 11.8 4.8 3.3 8.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX80901.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX80902.1 - 8.9e-56 187.8 7.4 9.9e-56 187.6 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX80903.1 - 8.3e-07 28.9 0.1 1.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX80904.1 - 2.3e-73 246.6 5.9 2.5e-73 246.5 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX80905.1 - 2.7e-27 94.6 28.4 1.1e-23 83.0 6.5 5.4 4 1 1 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX80905.1 - 0.023 14.4 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX80905.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF240 PF03086.14 EAX80905.1 - 0.59 10.1 5.3 2.7 7.9 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAX80905.1 - 1.6 8.3 28.9 0.086 12.4 7.5 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Polysacc_synt PF01943.17 EAX80906.1 - 0.0069 15.8 0.0 0.0079 15.6 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PapD_N PF00345.20 EAX80907.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX80908.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX80908.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX80908.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX80908.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX80909.1 - 0.0055 16.7 0.2 0.0075 16.3 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX80910.1 - 1e-23 84.1 5.3 1.5e-23 83.5 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX80910.1 - 0.02 15.0 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF3839 PF12943.7 EAX80911.1 - 1.5e-91 306.2 5.0 1.7e-91 306.0 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX80913.1 - 3.3e-72 241.9 3.6 4.3e-72 241.6 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX80915.1 - 2.2e-156 518.5 15.1 2.5e-156 518.3 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX80915.1 - 0.088 12.3 0.1 0.29 10.6 0.1 1.8 1 1 0 1 1 1 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX80915.1 - 0.16 11.8 1.2 0.57 10.0 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80915.1 - 0.62 10.5 8.1 1.7 9.2 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX80915.1 - 0.64 10.3 2.8 2.4 8.5 0.0 2.9 2 2 0 2 2 2 0 Rx N-terminal domain PTR PF12789.7 EAX80916.1 - 5e-20 71.3 7.9 7.2e-16 58.0 2.3 5.5 7 1 0 7 7 7 2 Phage tail repeat like DUF4795 PF16043.5 EAX80916.1 - 0.0062 16.2 0.2 0.0062 16.2 0.2 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX80917.1 - 2.9e-37 128.6 15.1 1.7e-36 126.1 15.1 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAX80919.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80919.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX80921.1 - 3.3e-72 241.9 3.6 4.3e-72 241.6 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2960 PF11173.8 EAX80922.1 - 0.03 14.7 0.3 0.071 13.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX80922.1 - 0.068 13.2 2.2 0.3 11.1 0.5 2.6 2 1 1 3 3 3 0 YpjP-like protein Ank_2 PF12796.7 EAX80923.1 - 7.3e-80 263.6 10.4 2.3e-13 50.5 0.1 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX80923.1 - 6.7e-61 201.6 4.0 1.5e-05 25.2 0.0 9.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX80923.1 - 4.8e-59 194.4 0.0 7.3e-05 23.0 0.0 9.6 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX80923.1 - 1.1e-53 179.0 1.5 9.5e-10 38.8 0.0 7.5 4 3 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX80923.1 - 6.9e-42 136.6 0.0 0.0082 16.6 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat DUF1147 PF06615.11 EAX80923.1 - 5.5e-08 32.7 12.8 16 5.7 0.0 8.1 9 0 0 9 9 9 5 Protein of unknown function (DUF1147) DUF1897 PF09005.10 EAX80923.1 - 1.3e-05 24.6 6.9 1.1e+02 2.4 0.0 10.1 12 0 0 12 12 12 0 Domain of unknown function (DUF1897) KH_4 PF13083.6 EAX80923.1 - 0.00083 19.2 6.4 1.2e+02 2.6 0.0 7.4 9 0 0 9 9 9 0 KH domain DUF1947 PF09183.10 EAX80923.1 - 0.088 13.1 11.2 1.3e+02 2.9 0.3 6.5 1 1 6 7 7 7 0 Domain of unknown function (DUF1947) STAT6_C PF14596.6 EAX80923.1 - 0.47 10.4 3.5 1.4e+02 2.3 0.0 4.7 1 1 6 7 7 7 0 STAT6 C-terminal DUF3839 PF12943.7 EAX80924.1 - 8.6e-156 516.5 12.4 1.1e-155 516.2 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX80924.1 - 0.035 14.5 1.9 0.16 12.4 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX80924.1 - 0.53 10.8 6.8 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX80924.1 - 1.4 9.5 6.8 0.42 11.2 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) YmgB PF10798.8 EAX80926.1 - 0.0099 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR DUF4108 PF13390.6 EAX80926.1 - 0.083 12.8 8.1 0.17 11.8 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX80927.1 - 2.3e-58 196.2 9.5 2.5e-58 196.0 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Laminin_I PF06008.14 EAX80928.1 - 3.4e-23 82.7 74.7 0.00067 19.4 7.6 7.9 1 1 8 9 9 9 9 Laminin Domain I KASH_CCD PF14662.6 EAX80928.1 - 4.6e-17 62.5 65.6 0.00011 22.1 9.3 6.0 1 1 4 6 6 6 6 Coiled-coil region of CCDC155 or KASH SNAP PF14938.6 EAX80928.1 - 3.9e-14 52.7 69.8 0.00075 19.0 11.7 5.0 1 1 4 5 5 5 5 Soluble NSF attachment protein, SNAP CheZ PF04344.13 EAX80928.1 - 2.4e-09 37.4 58.7 0.031 14.2 4.3 6.8 1 1 7 8 8 8 6 Chemotaxis phosphatase, CheZ Spc7 PF08317.11 EAX80928.1 - 1.9e-07 30.3 59.5 0.053 12.4 8.0 5.7 1 1 5 6 6 6 4 Spc7 kinetochore protein Sec34 PF04136.15 EAX80928.1 - 4.6e-07 29.8 102.7 1 9.3 3.3 11.0 1 1 13 14 14 14 9 Sec34-like family ERM PF00769.19 EAX80928.1 - 2.3e-06 27.6 56.8 0.49 10.2 9.4 5.4 1 1 4 5 5 5 5 Ezrin/radixin/moesin family ZapB PF06005.12 EAX80928.1 - 2.8e-05 24.5 41.9 1.7 9.1 0.7 10.0 2 2 8 10 10 10 2 Cell division protein ZapB DUF3450 PF11932.8 EAX80928.1 - 6.4e-05 22.4 107.0 0.072 12.4 7.6 7.1 1 1 6 7 7 7 5 Protein of unknown function (DUF3450) PhoU PF01895.19 EAX80928.1 - 9.5e-05 22.8 0.4 50 4.4 0.0 6.3 1 1 6 8 8 8 0 PhoU domain BLOC1_2 PF10046.9 EAX80928.1 - 9.6e-05 22.6 44.9 2.3 8.6 0.3 10.6 1 1 6 7 7 7 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EAX80928.1 - 0.00024 21.3 24.4 7.1 7.0 0.1 7.9 3 3 5 8 8 8 0 Bacterial protein of unknown function (DUF948) UPF0449 PF15136.6 EAX80928.1 - 0.00042 20.7 58.5 3.2 8.3 1.0 10.6 1 1 8 9 9 9 2 Uncharacterised protein family UPF0449 Laminin_II PF06009.12 EAX80928.1 - 0.00043 20.3 69.0 0.87 9.6 1.8 8.2 1 1 8 9 9 9 7 Laminin Domain II JIP_LZII PF16471.5 EAX80928.1 - 0.0015 18.7 24.7 15 5.9 0.0 11.4 2 2 9 14 14 14 0 JNK-interacting protein leucine zipper II YabA PF06156.13 EAX80928.1 - 0.0021 18.7 30.1 23 5.7 0.5 8.6 1 1 4 5 5 5 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 EAX80928.1 - 0.003 17.8 76.8 6 7.1 4.6 8.6 1 1 10 12 12 12 1 JNK_SAPK-associated protein-1 RNase_E_G PF10150.9 EAX80928.1 - 0.0038 16.7 22.7 0.74 9.2 0.4 5.7 1 1 3 5 5 5 2 Ribonuclease E/G family BRE1 PF08647.11 EAX80928.1 - 0.0065 16.5 60.9 1.8 8.7 0.7 8.1 1 1 9 10 10 10 4 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EAX80928.1 - 0.031 14.3 38.9 4.4 7.3 1.0 7.4 1 1 8 9 9 9 0 Protein of unknown function (DUF1664) CorA PF01544.18 EAX80928.1 - 0.096 12.0 59.2 0.29 10.4 4.4 6.8 1 1 6 7 7 7 0 CorA-like Mg2+ transporter protein TACC_C PF05010.14 EAX80928.1 - 0.15 11.9 43.7 1.6 8.5 3.8 4.9 1 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GCN5L1 PF06320.13 EAX80928.1 - 0.2 11.8 45.0 8.1 6.6 0.6 9.2 1 1 11 12 12 12 0 GCN5-like protein 1 (GCN5L1) TMP_2 PF06791.13 EAX80928.1 - 0.58 9.8 105.9 2.3 7.8 7.7 8.9 1 1 9 10 10 10 0 Prophage tail length tape measure protein TPR_MLP1_2 PF07926.12 EAX80928.1 - 0.93 9.6 115.6 2 8.5 15.3 7.3 1 1 8 9 9 9 0 TPR/MLP1/MLP2-like protein Serine_rich PF08824.10 EAX80928.1 - 2.8 7.9 100.8 4.2 7.3 12.4 6.7 1 1 6 7 7 7 0 Serine rich protein interaction domain CENP-F_leu_zip PF10473.9 EAX80928.1 - 3.1 7.8 47.5 2 8.4 4.1 6.0 1 1 7 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 EAX80928.1 - 3.2 7.2 99.2 11 5.5 18.0 5.2 1 1 2 3 3 2 0 Exonuclease VII, large subunit DUF4795 PF16043.5 EAX80928.1 - 4.6 6.8 62.5 4.2 6.9 1.6 8.0 1 1 3 4 4 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX80929.1 - 1.9e-155 515.4 13.5 2.3e-155 515.1 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80929.1 - 0.17 11.7 1.6 0.47 10.3 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80929.1 - 0.2 11.9 4.7 1.4 9.2 0.1 3.4 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX80929.1 - 0.45 11.0 6.3 2 8.9 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX80929.1 - 1.3 9.4 5.3 12 6.2 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal DUF4106 PF13388.6 EAX80930.1 - 9.7e-280 927.7 23.3 1.7e-279 926.9 23.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX80930.1 - 0.0015 18.8 0.1 0.057 13.7 0.2 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated Myc_N PF01056.18 EAX80931.1 - 0.068 13.1 1.4 0.076 12.9 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EAX80931.1 - 0.37 10.1 2.3 0.51 9.6 2.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAX80931.1 - 3.1 8.2 15.9 8.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain KilA-N PF04383.13 EAX80932.1 - 7.8e-38 128.8 1.6 1.1e-37 128.3 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80932.1 - 0.023 15.3 0.1 0.07 13.8 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX80933.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Gly-zipper_Omp PF13488.6 EAX80936.1 - 0.0025 17.8 10.1 0.0042 17.1 10.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX80936.1 - 0.067 13.1 0.2 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX80936.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX80936.1 - 0.18 12.1 4.7 0.29 11.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX80936.1 - 0.87 9.7 6.0 1.5 9.0 5.9 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DAGK_cat PF00781.24 EAX80937.1 - 2.8e-21 75.4 0.0 4.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 EAX80937.1 - 6.9e-14 52.5 0.0 1.2e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DUF3839 PF12943.7 EAX80938.1 - 8.8e-75 251.3 7.1 1.2e-74 250.9 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX80938.1 - 0.047 12.9 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II KilA-N PF04383.13 EAX80939.1 - 2.2e-41 140.2 1.2 3.6e-41 139.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX80939.1 - 0.012 14.9 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX80939.1 - 0.21 12.1 2.1 1.6 9.4 0.4 2.4 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 FPN1 PF06963.12 EAX80939.1 - 0.26 9.8 0.1 0.41 9.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) KilA-N PF04383.13 EAX80941.1 - 2.2e-41 140.2 0.6 6e-41 138.8 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX80941.1 - 0.011 15.0 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX80941.1 - 0.19 12.3 2.1 1.9 9.1 0.4 2.5 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 T5orf172 PF10544.9 EAX80942.1 - 2.6e-06 27.9 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80942.1 - 0.023 14.5 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX80942.1 - 0.22 11.0 0.8 2.4 7.6 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX80943.1 - 1.6e-76 257.0 11.0 2e-76 256.6 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX80944.1 - 2.5e-06 28.0 0.2 7.2e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80944.1 - 0.012 15.2 1.1 0.11 12.0 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX80944.1 - 0.015 15.2 0.1 0.072 12.9 0.1 2.1 2 0 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX80945.1 - 8.3e-17 61.1 0.2 1.6e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX80946.1 - 6.1e-07 29.1 2.9 9.1e-07 28.6 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80946.1 - 0.006 16.2 0.1 0.009 15.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF4795 PF16043.5 EAX80946.1 - 0.047 13.3 2.1 0.3 10.7 2.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Elong_Iki1 PF10483.9 EAX80946.1 - 0.051 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF2805 PF10985.8 EAX80946.1 - 0.061 13.7 1.9 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) IstB_IS21 PF01695.17 EAX80946.1 - 0.07 12.9 0.1 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80946.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80946.1 - 0.15 12.1 2.2 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX80946.1 - 0.16 12.4 2.3 0.22 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4107 PF13389.6 EAX80947.1 - 1.8e-48 164.7 1.1 2.5e-48 164.3 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX80947.1 - 0.069 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX80948.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX80949.1 - 4.6e-44 148.8 0.3 1.2e-43 147.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80949.1 - 0.0099 16.0 0.3 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX80949.1 - 0.3 9.6 0.1 0.47 9.0 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) tRNA_anti-codon PF01336.25 EAX80950.1 - 0.00015 21.7 0.1 4 7.5 0.1 4.5 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain DUF4107 PF13389.6 EAX80951.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX80952.1 - 0.0093 15.6 0.1 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_D5 PF03288.16 EAX80954.1 - 1.7e-05 25.2 0.4 2.9e-05 24.5 0.4 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX80954.1 - 0.026 15.1 0.2 0.035 14.7 0.2 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX80954.1 - 0.079 12.9 0.3 0.12 12.4 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX80955.1 - 3.7e-62 208.5 6.6 4.2e-62 208.3 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX80957.1 - 4.7e-06 26.2 1.9 7e-06 25.7 1.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX80957.1 - 0.0036 17.0 0.2 0.0052 16.5 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX80957.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX80957.1 - 0.035 13.6 0.1 0.046 13.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX80957.1 - 0.039 13.7 0.3 0.21 11.3 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX80957.1 - 0.046 13.5 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX80957.1 - 0.14 12.1 2.4 1.1 9.3 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX80957.1 - 0.43 10.8 8.8 4.6 7.5 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) AAA_22 PF13401.6 EAX80958.1 - 1.8e-05 25.1 0.1 0.00013 22.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX80958.1 - 2e-05 24.4 0.3 0.29 10.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX80958.1 - 9.1e-05 22.5 3.2 0.00018 21.6 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX80958.1 - 0.00039 20.2 0.1 0.00064 19.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX80958.1 - 0.0011 18.5 1.5 0.0011 18.5 1.5 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX80958.1 - 0.0012 18.8 0.8 0.003 17.4 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX80958.1 - 0.006 16.2 0.5 0.048 13.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX80958.1 - 0.0097 16.2 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX80958.1 - 0.037 13.6 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX80958.1 - 0.054 13.9 0.1 0.44 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX80958.1 - 0.055 13.0 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX80958.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX80958.1 - 0.44 10.8 5.1 7.1 6.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX80959.1 - 1.9e-08 34.2 7.9 9.2e-08 32.0 2.4 4.3 5 1 1 6 6 6 2 Phage tail repeat like EpuA PF11772.8 EAX80959.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX80959.1 - 0.65 9.9 4.8 0.9 9.5 1.1 2.7 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Alpha-2-MRAP_C PF06401.11 EAX80959.1 - 1 9.3 6.2 0.28 11.1 2.8 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Trypan_PARP PF05887.11 EAX80960.1 - 0.81 9.7 8.6 0.95 9.4 8.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX80961.1 - 0.037 13.0 0.1 0.037 13.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDR PF08841.10 EAX80963.1 - 0.037 13.0 0.1 0.037 13.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX80964.1 - 3.1e-29 102.2 6.5 5.5e-29 101.3 6.5 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX80964.1 - 0.086 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX80966.1 - 1.9e-157 521.9 12.4 2.4e-157 521.6 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80966.1 - 0.12 12.7 0.6 3 8.2 0.0 3.1 3 1 1 4 4 4 0 Rx N-terminal domain Tup_N PF08581.10 EAX80966.1 - 0.3 11.4 3.4 15 6.0 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX80966.1 - 0.35 11.4 6.2 0.72 10.3 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX80968.1 - 1.3e-39 134.5 0.8 2.5e-39 133.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX80968.1 - 0.0063 17.1 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 Parathyroid hormone family T5orf172 PF10544.9 EAX80969.1 - 1.8e-06 28.4 0.1 4.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX80969.1 - 0.077 12.5 0.7 1.5 8.3 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain IstB_IS21_ATP PF08483.11 EAX80970.1 - 4.5e-08 32.9 0.7 7e+02 0.2 0.0 13.6 18 0 0 18 18 18 0 IstB-like ATP binding N-terminal LDB19 PF13002.7 EAX80970.1 - 6.4e-07 29.3 13.5 8.6 6.0 0.0 7.4 1 1 7 9 9 9 5 Arrestin_N terminal like BORG_CEP PF14957.6 EAX80970.1 - 0.00076 20.6 52.7 8.6 7.5 1.6 9.9 2 1 5 7 7 7 4 Cdc42 effector KAAG1 PF15354.6 EAX80970.1 - 0.0014 19.1 49.5 3.4 8.3 0.7 9.8 1 1 11 13 13 13 5 Kidney-associated antigen 1 PK_C PF02887.16 EAX80970.1 - 0.0029 17.8 19.2 10 6.4 0.7 7.4 4 3 2 6 6 6 1 Pyruvate kinase, alpha/beta domain DUF2089 PF09862.9 EAX80970.1 - 0.38 10.8 6.7 18 5.4 0.1 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF2089) Baculo_p26 PF04766.12 EAX80970.1 - 0.57 9.6 25.3 0.55 9.6 1.1 4.8 1 1 5 6 6 6 0 Nucleopolyhedrovirus p26 protein PTR PF12789.7 EAX80971.1 - 4.6e-13 49.0 37.4 2e-08 34.1 4.3 6.5 7 0 0 7 7 7 4 Phage tail repeat like LIFR_D2 PF17971.1 EAX80971.1 - 0.01 16.0 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain RecG_N PF17190.4 EAX80971.1 - 0.78 10.5 6.4 34 5.3 0.0 4.1 4 0 0 4 4 4 0 RecG N-terminal helical domain DUF4286 PF14114.6 EAX80974.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) DUF1947 PF09183.10 EAX80975.1 - 0.023 15.0 1.0 0.12 12.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) EpuA PF11772.8 EAX80975.1 - 0.03 14.0 0.0 0.096 12.4 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF3781 PF12636.7 EAX80977.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX80978.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX80978.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX80979.1 - 0.029 14.3 8.5 0.044 13.7 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX80979.1 - 2.3 8.6 6.2 3.4 8.1 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX80980.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX80981.1 - 6.3e-07 29.9 0.3 1.3e-06 28.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80982.1 - 2.7e-34 117.4 1.3 3.2e-34 117.1 0.1 1.7 2 1 1 3 3 3 1 KilA-N domain RPAP3_C PF13877.6 EAX80982.1 - 0.018 15.6 0.1 0.041 14.4 0.1 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Parathyroid PF01279.17 EAX80982.1 - 0.019 15.6 0.0 0.047 14.3 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX80983.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX80984.1 - 1.4e-33 115.0 1.6 1.8e-33 114.8 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX80984.1 - 0.02 15.1 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX80984.1 - 0.038 14.4 4.1 2.2 8.8 1.3 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 KilA-N PF04383.13 EAX80985.1 - 1.2e-41 141.1 0.0 1.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Trypan_PARP PF05887.11 EAX80986.1 - 0.12 12.4 7.6 0.18 11.7 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX80987.1 - 0.049 14.1 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX80989.1 - 2.1e-155 515.3 14.2 2.6e-155 515.0 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX80989.1 - 0.066 13.5 0.5 1.6 9.0 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX80989.1 - 0.12 12.8 0.4 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX80989.1 - 0.2 11.5 1.5 0.59 10.0 0.5 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX80989.1 - 0.43 11.1 7.4 2.5 8.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80990.1 - 6.8e-81 271.3 10.4 8.8e-81 270.9 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX80990.1 - 0.055 14.0 0.5 0.098 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX80992.1 - 1.8e-10 40.3 1.2 3.8e-09 36.0 0.4 2.2 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX80992.1 - 0.1 11.3 1.6 4.3 5.9 1.4 3.0 2 1 0 2 2 2 0 DNA polymerase family B PapD_N PF00345.20 EAX80993.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX80993.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Amidase02_C PF12123.8 EAX80994.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX80995.1 - 3.3e-154 511.3 13.3 4.2e-154 511.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX80995.1 - 0.13 12.1 0.7 0.46 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX80995.1 - 0.41 10.9 2.9 6.8 7.0 0.0 3.4 2 1 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX80995.1 - 2.2 8.8 6.3 1.2 9.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX80995.1 - 3.3 8.2 7.4 1.8 9.1 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX80996.1 - 5.8e-89 297.7 7.7 7.2e-89 297.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glyco_hydro_30 PF02055.16 EAX80997.1 - 4.1e-45 154.3 3.1 5.2e-45 153.9 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAX80997.1 - 3.3e-11 43.0 0.3 5.6e-11 42.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAX80997.1 - 0.0001 22.1 0.1 0.26 10.8 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 TLE_N PF03920.15 EAX80999.1 - 0.031 14.4 0.4 0.072 13.2 0.2 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DDE_Tnp_ISL3 PF01610.17 EAX80999.1 - 0.046 13.4 0.1 0.093 12.4 0.1 1.5 1 1 0 1 1 1 0 Transposase FadA PF09403.10 EAX80999.1 - 0.11 13.0 6.9 4.5 7.8 4.7 2.9 1 1 1 2 2 2 0 Adhesion protein FadA PET PF06297.14 EAX80999.1 - 0.79 10.1 3.5 2.1 8.7 0.4 2.3 1 1 1 2 2 2 0 PET Domain Myosin_TH1 PF06017.13 EAX81000.1 - 3.8e-18 65.8 3.3 4.3e-18 65.7 3.3 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding G-alpha PF00503.20 EAX81001.1 - 1e-33 117.0 0.1 1.3e-33 116.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF1955 PF09205.10 EAX81001.1 - 0.01 15.6 0.1 0.026 14.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) KilA-N PF04383.13 EAX81002.1 - 2.9e-40 136.6 0.6 6.1e-40 135.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81002.1 - 0.022 14.9 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_D5 PF03288.16 EAX81003.1 - 9.2e-05 22.9 3.3 0.00057 20.3 3.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX81003.1 - 0.045 14.4 0.2 0.093 13.4 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4107 PF13389.6 EAX81005.1 - 1.5e-71 239.8 3.5 2.3e-71 239.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81005.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF357 PF04010.13 EAX81007.1 - 0.029 14.4 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DUF4456 PF14644.6 EAX81007.1 - 0.061 13.0 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) ApoO PF09769.9 EAX81007.1 - 0.097 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O DUF768 PF05589.11 EAX81007.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF768) GPS2_interact PF15784.5 EAX81009.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81009.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81010.1 - 0.062 13.3 4.5 0.071 13.1 4.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NAD_Gly3P_dh_C PF07479.14 EAX81011.1 - 8.8e-37 126.5 0.3 1.1e-36 126.3 0.3 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EAX81011.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3839 PF12943.7 EAX81012.1 - 7.3e-156 516.8 13.1 9.2e-156 516.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81012.1 - 0.037 13.9 0.8 0.11 12.4 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX81012.1 - 0.31 11.5 1.8 1.9 8.9 0.4 2.3 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81012.1 - 6.6 7.3 7.8 1.8 9.1 0.6 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX81013.1 - 6.5e-08 32.3 1.1 7.7e-08 32.1 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81013.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81013.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81013.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX81014.1 - 1.5e-41 140.7 1.2 2.3e-41 140.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81015.1 - 9.3e-103 342.9 6.6 1.1e-102 342.7 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81015.1 - 0.048 13.1 0.3 0.064 12.8 0.3 1.3 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX81015.1 - 0.22 12.2 2.0 0.43 11.2 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX81017.1 - 2e-156 518.6 13.8 2.5e-156 518.3 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81017.1 - 0.097 12.9 0.3 2 8.8 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX81017.1 - 0.26 11.1 1.8 0.71 9.7 0.5 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81017.1 - 0.73 10.3 5.7 4.5 7.8 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 EAX81019.1 - 0.035 14.2 0.2 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81019.1 - 0.085 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81019.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3781 PF12636.7 EAX81020.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX81021.1 - 2.3e-66 222.9 13.3 1.1e-64 217.4 13.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81021.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX81023.1 - 5.3e-07 29.3 3.0 7.9e-07 28.8 3.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81023.1 - 0.0051 16.5 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81023.1 - 0.038 13.7 0.3 0.54 10.0 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81023.1 - 0.2 11.6 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX81023.1 - 0.37 11.0 8.3 5.7 7.1 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX81024.1 - 1.2e-117 391.6 7.2 1.4e-117 391.4 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81024.1 - 0.13 12.5 0.9 9.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Rx N-terminal domain EpuA PF11772.8 EAX81025.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF1477 PF07346.11 EAX81026.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) HTH_40 PF14493.6 EAX81026.1 - 0.12 12.9 0.8 2.6 8.6 0.8 2.6 1 1 0 1 1 1 0 Helix-turn-helix domain DUF3746 PF12562.8 EAX81026.1 - 0.21 11.5 1.8 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF4108 PF13390.6 EAX81027.1 - 1.6e-57 193.4 3.7 1.8e-57 193.3 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX81029.1 - 3.4e-07 30.0 4.0 3.4e-07 30.0 4.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81029.1 - 3.1e-05 24.3 0.6 0.00024 21.4 0.6 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81029.1 - 3.9e-05 23.5 0.9 0.36 10.5 0.1 2.8 2 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81029.1 - 0.00023 21.2 4.4 0.0005 20.1 4.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81029.1 - 0.00049 19.9 0.1 0.001 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81029.1 - 0.00066 19.6 0.6 0.0011 18.8 0.6 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81029.1 - 0.0094 16.3 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81029.1 - 0.015 15.0 1.2 0.08 12.6 1.2 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 EAX81029.1 - 0.063 12.8 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX81029.1 - 0.067 13.6 0.1 0.77 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81029.1 - 0.085 12.3 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81029.1 - 0.29 11.4 3.7 11 6.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Ribosomal_L6e PF01159.19 EAX81030.1 - 6.5e-10 39.5 0.2 0.00068 20.1 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L6e KOW PF00467.29 EAX81030.1 - 1.3 9.1 7.8 0.38 10.8 4.1 2.1 2 1 1 3 3 3 0 KOW motif DUF4108 PF13390.6 EAX81032.1 - 6.8e-59 197.9 6.0 7.6e-59 197.7 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX81033.1 - 2.7e-05 24.7 0.4 7.6e-05 23.2 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81033.1 - 0.0014 18.2 0.4 0.15 11.6 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain Pox_A32 PF04665.12 EAX81034.1 - 6.6e-08 32.3 0.9 8e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81034.1 - 0.003 17.2 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81034.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81034.1 - 0.091 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX81034.1 - 0.13 12.7 1.3 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Pox_A32 PF04665.12 EAX81036.1 - 3.4e-07 30.0 2.1 3.4e-07 30.0 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81036.1 - 3.1e-05 24.3 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81036.1 - 3.6e-05 23.6 0.3 0.32 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81036.1 - 0.00013 22.0 3.3 0.00032 20.7 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81036.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81036.1 - 0.0013 18.6 0.6 0.0027 17.6 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81036.1 - 0.0013 18.4 0.6 0.0097 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81036.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81036.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX81036.1 - 0.087 12.3 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX81036.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX81036.1 - 0.22 11.8 4.5 4.3 7.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX81037.1 - 1.6e-24 86.6 5.3 2.9e-24 85.8 5.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX81037.1 - 0.012 14.9 0.4 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein GGDEF PF00990.21 EAX81039.1 - 0.06 13.1 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX81040.1 - 4.1e-54 182.4 5.7 4.6e-54 182.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) CREPT PF16566.5 EAX81041.1 - 0.028 14.6 0.2 0.059 13.5 0.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX81041.1 - 0.61 10.3 5.3 0.29 11.3 1.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3839 PF12943.7 EAX81042.1 - 1.3e-153 509.3 13.6 1.7e-153 509.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81042.1 - 3.9 8.0 6.7 1.7 9.1 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF983 PF06170.12 EAX81043.1 - 0.97 9.9 5.1 0.66 10.4 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) KilA-N PF04383.13 EAX81044.1 - 5.5e-33 113.1 0.9 9.5e-33 112.4 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81044.1 - 0.0013 18.8 0.1 0.0039 17.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX81044.1 - 0.043 14.3 4.7 0.26 11.7 1.1 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX81045.1 - 1.1e-07 31.6 2.6 1.5e-07 31.1 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81045.1 - 0.0026 17.4 0.2 0.0034 17.1 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81045.1 - 0.056 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81045.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81045.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81045.1 - 0.11 12.5 2.8 0.44 10.5 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX81045.1 - 0.4 10.9 8.8 3 8.1 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) TMP PF05017.14 EAX81047.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX81048.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX81049.1 - 6.7e-118 392.5 7.2 7.8e-118 392.2 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX81049.1 - 0.25 11.7 1.2 0.56 10.5 1.2 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Imm70 PF15601.6 EAX81050.1 - 0.0059 16.1 15.6 8.7 5.9 0.2 5.2 1 1 4 5 5 5 5 Immunity protein 70 GIIM PF08388.11 EAX81050.1 - 3.6 7.7 5.3 1.1e+02 2.9 0.0 4.0 1 1 4 6 6 6 0 Group II intron, maturase-specific domain Ank_2 PF12796.7 EAX81052.1 - 1e-05 26.0 0.5 0.073 13.7 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX81052.1 - 0.0016 18.4 2.6 0.0016 18.4 2.6 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX81052.1 - 0.0028 18.0 0.1 26 5.8 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX81052.1 - 0.031 14.7 0.1 14 6.3 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EAX81052.1 - 0.042 14.4 0.2 43 4.9 0.0 3.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF3839 PF12943.7 EAX81054.1 - 2.6e-104 348.0 8.5 3e-104 347.7 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX81054.1 - 0.067 13.7 0.8 2.6 8.6 0.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX81054.1 - 0.073 13.5 1.3 6.2 7.4 0.0 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX81055.1 - 1.7e-06 28.5 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81055.1 - 0.007 16.2 0.9 0.048 13.5 0.3 2.4 2 1 0 2 2 2 1 KilA-N domain DUF3781 PF12636.7 EAX81056.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF563 PF04577.14 EAX81058.1 - 6.4e-20 72.2 0.0 1.3e-19 71.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PAS_6 PF08348.11 EAX81058.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 YheO-like PAS domain KilA-N PF04383.13 EAX81059.1 - 7.1e-23 80.6 0.4 2.2e-22 79.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX81060.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX81062.1 - 6.5e-07 29.9 0.2 1.3e-06 28.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX81063.1 - 3.3e-157 521.2 15.3 4.2e-157 520.8 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81063.1 - 1.1 9.7 7.8 2.3 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Meiosis_expr PF15163.6 EAX81065.1 - 0.028 15.1 1.2 0.035 14.8 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed DUF365 PF04033.12 EAX81065.1 - 0.044 14.1 0.4 0.059 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Spo12 PF05032.12 EAX81065.1 - 0.82 9.6 10.0 0.17 11.8 2.9 2.9 4 0 0 4 4 4 0 Spo12 family DUF3839 PF12943.7 EAX81067.1 - 3.5e-152 504.7 13.0 4.2e-152 504.4 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Suc_Fer-like PF06999.12 EAX81067.1 - 0.14 12.0 0.3 0.26 11.1 0.2 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like DUF2408 PF10303.9 EAX81067.1 - 1.1 9.9 4.2 1.7 9.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MG2 PF01835.19 EAX81068.1 - 2.3e-06 28.0 1.1 0.01 16.3 0.1 3.5 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX81068.1 - 0.00028 21.1 3.7 0.04 14.2 0.1 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) NPCBM_assoc PF10633.9 EAX81068.1 - 0.013 15.7 4.0 0.11 12.8 0.1 3.8 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ChitinaseA_N PF08329.10 EAX81068.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain He_PIG PF05345.12 EAX81068.1 - 0.019 15.1 0.4 0.41 10.9 0.1 3.2 2 0 0 2 2 2 0 Putative Ig domain DUF2914 PF11141.8 EAX81068.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Sipho_Gp157 PF05565.11 EAX81068.1 - 0.082 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Siphovirus Gp157 bMG6 PF17962.1 EAX81068.1 - 0.082 13.1 1.0 5.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 RIFIN PF02009.16 EAX81068.1 - 0.35 10.7 8.4 0.48 10.3 8.4 1.2 1 0 0 1 1 1 0 Rifin Pox_A32 PF04665.12 EAX81070.1 - 3.4e-07 30.0 2.5 3.4e-07 30.0 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81070.1 - 2.7e-05 24.5 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81070.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81070.1 - 0.00014 21.9 3.0 0.00034 20.7 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81070.1 - 0.00053 19.8 0.1 0.00097 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81070.1 - 0.0014 18.5 0.7 0.0026 17.6 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81070.1 - 0.0014 18.3 0.6 0.0097 15.6 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81070.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81070.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81070.1 - 0.09 13.2 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81070.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81070.1 - 0.41 10.9 4.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX81071.1 - 2.3e-40 138.6 5.1 3.3e-40 138.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX81071.1 - 0.062 13.4 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF2408 PF10303.9 EAX81071.1 - 0.071 13.7 0.6 0.083 13.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX81071.1 - 0.073 13.5 0.8 0.49 10.9 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB PRD PF00874.20 EAX81071.1 - 0.092 13.1 0.8 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 PRD domain LD_cluster2 PF18163.1 EAX81071.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 GalP_UDP_transf PF01087.22 EAX81071.1 - 0.37 11.2 2.9 1.1 9.6 1.2 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3781 PF12636.7 EAX81072.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX81075.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FAR1 PF03101.15 EAX81076.1 - 0.026 15.2 0.1 0.053 14.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Ras PF00071.22 EAX81077.1 - 1.9e-06 27.6 0.4 2.2e-06 27.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX81077.1 - 7.3e-06 26.2 0.2 8.2e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX81077.1 - 0.00015 21.8 0.2 0.00016 21.8 0.2 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX81077.1 - 0.0017 18.1 0.3 0.027 14.2 0.3 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 EAX81077.1 - 0.005 16.3 0.1 0.0054 16.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EAX81077.1 - 0.0099 15.4 0.3 0.017 14.6 0.1 1.5 1 1 1 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAX81077.1 - 0.012 15.6 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EAX81077.1 - 0.064 13.5 0.2 0.088 13.1 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX81077.1 - 0.11 12.2 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 EAX81077.1 - 0.13 12.2 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Microtubule binding GPS2_interact PF15784.5 EAX81079.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4107 PF13389.6 EAX81081.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX81082.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase GPS2_interact PF15784.5 EAX81084.1 - 0.023 15.1 0.5 0.024 15.0 0.5 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX81087.1 - 7.2e-119 395.6 11.8 8.9e-119 395.3 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81087.1 - 0.037 14.5 3.2 1.7 9.2 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX81087.1 - 0.047 14.1 0.1 0.071 13.6 0.1 1.3 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX81087.1 - 0.12 12.9 1.6 0.19 12.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) BRE1 PF08647.11 EAX81087.1 - 0.36 10.9 3.4 1.3 9.1 2.2 2.3 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4107 PF13389.6 EAX81091.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81091.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX81093.1 - 1.6e-31 108.5 0.3 4.4e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81094.1 - 4.5e-07 30.3 0.4 9.2e-07 29.4 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain LRR_5 PF13306.6 EAX81095.1 - 1.1e-80 267.8 67.4 2.5e-24 85.7 10.9 5.5 3 3 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX81095.1 - 8.8e-18 63.8 7.8 0.0028 17.4 0.0 8.2 7 1 1 8 8 8 7 Leucine rich repeat CBM49 PF09478.10 EAX81095.1 - 0.053 13.8 0.9 2.8 8.3 0.0 3.3 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 Toxin_2 PF00451.19 EAX81095.1 - 0.62 10.4 2.8 29 5.1 0.2 3.4 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Keratin_matx PF04579.12 EAX81095.1 - 0.83 10.0 4.7 3.3 8.1 0.2 3.2 2 1 1 3 3 3 0 Keratin, high-sulphur matrix protein AAA_22 PF13401.6 EAX81097.1 - 1.6e-05 25.2 0.1 0.00013 22.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81097.1 - 0.00011 22.3 3.0 0.0002 21.4 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81097.1 - 0.00054 19.8 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81097.1 - 0.0013 18.6 0.9 0.0044 16.9 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81097.1 - 0.0017 18.1 0.3 0.3 10.8 0.0 2.8 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX81097.1 - 0.0095 16.3 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX81097.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX81097.1 - 0.096 13.1 0.0 0.45 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX81097.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX81097.1 - 0.43 10.9 4.8 6.9 7.0 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Collagen_bind_2 PF12904.7 EAX81100.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAX81101.1 - 6.1e-47 159.8 2.2 8.5e-47 159.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX81102.1 - 0.02 14.8 8.6 0.032 14.2 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81102.1 - 3.6 8.0 5.0 5.1 7.5 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81103.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81103.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX81105.1 - 9.3e-53 178.7 1.1 1.4e-52 178.1 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) SGP PF17228.2 EAX81105.1 - 0.03 15.2 0.1 0.056 14.3 0.1 1.4 1 0 0 1 1 1 0 Sulphur globule protein DUF1476 PF07345.11 EAX81105.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta P22_AR_C PF10548.9 EAX81106.1 - 0.091 12.9 0.1 21 5.4 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain KilA-N PF04383.13 EAX81107.1 - 1.4e-06 28.1 0.9 1.9e-06 27.7 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81108.1 - 8.1e-128 424.9 7.1 9.2e-128 424.8 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX81108.1 - 0.14 11.6 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX81108.1 - 0.26 11.8 2.3 1.2 9.6 0.8 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX81110.1 - 6.1e-31 106.6 0.4 1.5e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81111.1 - 1.2e-138 460.3 14.0 1.5e-138 460.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81111.1 - 0.022 15.2 2.5 1.9 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81113.1 - 5.3e-155 513.9 14.0 6.4e-155 513.7 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81113.1 - 0.3 11.6 5.5 1.9 9.0 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81116.1 - 8.8e-155 513.2 15.3 1.1e-154 512.9 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81116.1 - 0.055 13.7 4.9 0.35 11.2 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX81116.1 - 0.12 12.2 1.5 0.29 11.0 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81116.1 - 0.26 11.8 6.8 2 9.0 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81116.1 - 0.26 11.8 4.4 1.2 9.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX81118.1 - 2.9e-148 491.9 15.9 3.6e-148 491.6 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81118.1 - 0.074 13.5 2.4 0.29 11.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81118.1 - 0.33 11.4 6.6 2.4 8.7 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX81118.1 - 0.56 10.9 3.9 0.63 10.7 0.2 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX81118.1 - 0.9 9.9 5.3 4.1 7.8 0.0 3.4 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX81118.1 - 1.3 9.6 7.1 0.43 11.1 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX81119.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDE_1 PF03184.19 EAX81121.1 - 1.2e-08 34.8 1.1 1.4e-08 34.6 0.2 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease KilA-N PF04383.13 EAX81122.1 - 4.3e-09 36.2 0.1 1.2e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain Syja_N PF02383.18 EAX81122.1 - 0.099 11.9 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 SacI homology domain NTS PF15447.6 EAX81122.1 - 0.17 12.4 3.2 1.8 9.1 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX81123.1 - 5.9e-156 517.1 16.4 7.4e-156 516.7 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81123.1 - 0.078 13.4 3.2 0.17 12.3 0.8 2.1 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX81123.1 - 0.36 11.2 2.2 2 8.9 0.4 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81123.1 - 0.46 11.0 8.7 2.4 8.7 0.7 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81123.1 - 8 6.9 8.1 13 6.1 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal DDR PF08841.10 EAX81125.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX81125.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX81126.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX81127.1 - 6.9e-121 402.2 12.1 9e-121 401.8 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81127.1 - 0.029 14.8 0.4 0.047 14.1 0.4 1.4 1 0 0 1 1 1 0 Fez1 KELK PF15796.5 EAX81127.1 - 0.031 14.7 3.3 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81127.1 - 0.16 12.6 2.5 0.18 12.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) MULE PF10551.9 EAX81129.1 - 1.4e-13 51.0 0.1 3.1e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX81129.1 - 0.05 13.3 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Transposase MCM6_C PF18263.1 EAX81129.1 - 0.83 9.9 6.7 1.5 9.1 6.7 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain GPS2_interact PF15784.5 EAX81130.1 - 0.11 13.0 1.6 0.15 12.5 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81130.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81131.1 - 0.046 13.7 9.0 0.062 13.3 9.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81131.1 - 2.4 8.6 6.0 3.1 8.2 6.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin T5orf172 PF10544.9 EAX81132.1 - 0.0001 22.8 0.3 0.00027 21.4 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81132.1 - 0.16 11.5 0.3 2.7 7.4 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81133.1 - 5.9e-148 490.9 15.7 7.2e-148 490.6 15.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX81133.1 - 0.079 13.4 0.2 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81133.1 - 0.091 13.2 8.3 1.9 9.0 1.4 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF563 PF04577.14 EAX81134.1 - 6.9e-22 78.6 0.1 1.1e-21 78.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Chal_sti_synt_N PF00195.19 EAX81135.1 - 0.071 12.5 0.2 0.13 11.6 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX81135.1 - 3.5 7.5 7.7 8.5 6.2 7.7 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA GPS2_interact PF15784.5 EAX81136.1 - 0.096 13.1 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81136.1 - 0.12 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81137.1 - 0.19 11.7 10.1 0.2 11.6 10.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81137.1 - 0.59 10.6 5.4 0.67 10.4 5.4 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amidase02_C PF12123.8 EAX81138.1 - 0.0075 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX81139.1 - 4.1e-72 241.6 3.7 5.4e-72 241.2 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX81140.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX81142.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX81142.1 - 0.077 13.0 0.4 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX81142.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX81143.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX81143.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ResIII PF04851.15 EAX81145.1 - 2.1e-05 24.6 0.9 3.3e-05 23.9 0.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81145.1 - 0.00032 20.5 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX81145.1 - 0.00037 20.8 0.0 0.00057 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX81145.1 - 0.0015 18.3 0.1 0.0021 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81145.1 - 0.007 16.7 0.0 0.0087 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX81145.1 - 0.036 13.5 0.1 0.082 12.3 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX81145.1 - 0.061 13.0 0.3 0.097 12.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX81145.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX81145.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX81145.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX81145.1 - 0.31 10.5 3.6 0.082 12.4 0.9 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase APG12 PF04110.13 EAX81145.1 - 0.64 10.5 3.2 0.42 11.1 0.5 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX81147.1 - 3.4e-126 419.6 7.9 3.9e-126 419.4 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_4 PF13637.6 EAX81148.1 - 5e-10 39.7 0.2 0.0012 19.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX81148.1 - 9.9e-09 35.7 0.9 8.4e-05 23.1 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX81148.1 - 0.00046 20.4 0.2 5 8.0 0.0 4.9 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 EAX81148.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DUF3839 PF12943.7 EAX81149.1 - 6.7e-142 471.0 11.6 8e-142 470.8 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81149.1 - 0.47 10.9 6.6 3.1 8.3 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CDI PF02234.19 EAX81150.1 - 0.014 15.6 0.4 0.043 14.0 0.1 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor LRR_3 PF07725.12 EAX81150.1 - 0.026 14.4 0.3 0.051 13.4 0.3 1.5 1 0 0 1 1 1 0 Leucine Rich Repeat LRR_4 PF12799.7 EAX81150.1 - 0.058 13.8 0.3 0.28 11.7 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3922 PF13059.6 EAX81150.1 - 0.094 13.2 0.2 0.24 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DUF3839 PF12943.7 EAX81153.1 - 9.3e-146 483.7 11.6 1.3e-145 483.1 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX81153.1 - 5.8e-06 26.8 0.1 7.6e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81153.1 - 0.055 13.0 0.6 0.55 9.7 0.2 2.1 2 0 0 2 2 2 0 Legume lectin domain NTP_transf_6 PF06042.11 EAX81153.1 - 0.13 12.1 0.6 0.41 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX81154.1 - 3.6e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81154.1 - 0.0057 16.3 0.2 0.0075 15.9 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81154.1 - 0.039 13.4 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81154.1 - 0.062 13.0 0.1 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81154.1 - 0.063 13.0 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81154.1 - 0.14 12.1 2.1 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX81154.1 - 0.15 12.5 2.3 0.21 12.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX81155.1 - 9.6e-75 251.1 9.8 1.3e-74 250.7 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81155.1 - 0.064 13.1 1.3 0.28 11.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX81157.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMP PF05017.14 EAX81160.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX81161.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX81163.1 - 3.2e-80 269.1 11.6 4.1e-80 268.7 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX81163.1 - 0.081 12.4 0.4 0.46 10.0 0.0 2.1 2 1 1 3 3 3 0 SLOG cluster2 KilA-N PF04383.13 EAX81164.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX81164.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX81164.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX81165.1 - 4.6e-157 520.7 11.8 5.6e-157 520.4 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81165.1 - 0.3 11.6 6.9 2.3 8.8 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81165.1 - 4.3 7.7 7.7 8.8 6.7 0.1 3.8 3 2 1 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX81166.1 - 6e-07 29.2 2.6 6e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81166.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81166.1 - 7e-05 22.6 0.3 0.49 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81166.1 - 0.00011 22.2 2.8 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81166.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81166.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81166.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81166.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX81166.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX81166.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81166.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81166.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81166.1 - 0.3 11.3 4.1 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) ANAPC15 PF15243.6 EAX81167.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 EMP24_GP25L PF01105.24 EAX81167.1 - 1.3 8.9 6.0 1.6 8.6 6.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 EAX81167.1 - 1.7 8.8 13.1 1.9 8.5 13.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EAX81167.1 - 6.9 5.7 13.5 7.6 5.5 13.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sugar_tr PF00083.24 EAX81168.1 - 1.9e-13 50.1 1.8 2.4e-13 49.8 1.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX81168.1 - 3.9e-07 29.3 8.7 4.6e-07 29.1 8.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAX81168.1 - 0.0027 16.3 2.4 0.0031 16.2 2.4 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 EAX81169.1 - 4.5e-18 65.3 6.2 5.7e-18 65.0 6.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX81169.1 - 5.1e-09 35.5 12.6 6.2e-09 35.2 12.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily START PF01852.19 EAX81170.1 - 1.8e-11 43.9 0.0 5.4e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 START domain S-layer PF07752.11 EAX81170.1 - 0.031 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 S-layer protein T5orf172 PF10544.9 EAX81172.1 - 8.7e-07 29.4 0.2 1.7e-06 28.5 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX81172.1 - 0.11 13.2 0.3 0.31 11.7 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX81173.1 - 7e-41 138.6 0.6 1.4e-40 137.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81173.1 - 0.00061 19.9 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX81173.1 - 0.076 13.5 2.5 0.61 10.6 2.7 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Acyl_transf_2 PF02273.15 EAX81173.1 - 0.091 12.0 0.1 0.32 10.2 0.0 1.8 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX81173.1 - 0.16 10.5 0.1 0.27 9.8 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX81174.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81174.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81174.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81174.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4107 PF13389.6 EAX81175.1 - 1.8e-63 213.5 2.2 2.4e-63 213.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX81176.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DDR PF08841.10 EAX81177.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DHR-2 PF06920.13 EAX81178.1 - 0.03 13.0 0.2 0.033 12.8 0.2 1.0 1 0 0 1 1 1 0 Dock homology region 2 DpnI_C PF17726.1 EAX81178.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain PTR PF12789.7 EAX81179.1 - 3.9e-23 81.3 23.4 4.3e-16 58.7 3.1 4.9 6 0 0 6 6 6 2 Phage tail repeat like DUF240 PF03086.14 EAX81179.1 - 0.67 9.9 6.1 2.8 7.9 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX81180.1 - 0.0074 16.7 0.7 0.014 15.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DUF3781 PF12636.7 EAX81182.1 - 0.024 14.5 1.0 0.04 13.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) L27_1 PF09058.10 EAX81183.1 - 0.01 15.8 3.3 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 L27_1 CREPT PF16566.5 EAX81183.1 - 0.044 14.0 0.9 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX81183.1 - 0.091 12.8 0.8 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX81183.1 - 0.9 9.7 7.2 0.47 10.6 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4108 PF13390.6 EAX81185.1 - 3.1e-58 195.8 8.6 3.4e-58 195.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX81186.1 - 8.3e-05 23.0 2.5 0.00043 20.7 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX81186.1 - 0.099 12.6 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DDR PF08841.10 EAX81187.1 - 0.11 11.5 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81188.1 - 0.1 12.5 9.5 0.13 12.2 9.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX81190.1 - 3.5e-62 208.6 8.4 3.9e-62 208.4 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX81191.1 - 4.7e-05 23.8 2.9 0.00042 20.7 2.9 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Pox_A32 PF04665.12 EAX81192.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81192.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81192.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81192.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81192.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81192.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81192.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81192.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81192.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81192.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81192.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81192.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX81193.1 - 6.1e-25 87.2 0.6 2e-24 85.6 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81194.1 - 1.6e-156 518.9 13.1 1.9e-156 518.7 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81194.1 - 0.42 11.1 6.6 1.6 9.2 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Metallophos PF00149.28 EAX81196.1 - 2.1e-31 110.1 2.1 3.1e-31 109.5 2.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX81196.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Meiosis_expr PF15163.6 EAX81197.1 - 0.0062 17.2 1.0 0.0092 16.6 0.4 1.6 2 0 0 2 2 2 1 Meiosis-expressed Spo12 PF05032.12 EAX81197.1 - 1.4 8.9 11.1 0.14 12.0 2.8 3.2 4 1 0 4 4 4 0 Spo12 family UQ_con PF00179.26 EAX81198.1 - 1.1e-43 148.2 0.4 1.3e-43 148.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAX81198.1 - 0.012 15.9 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 0 RWD domain T5orf172 PF10544.9 EAX81199.1 - 0.00027 21.4 0.3 0.0006 20.3 0.3 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX81200.1 - 2.3e-120 400.5 12.1 2.9e-120 400.2 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81200.1 - 0.015 15.7 2.5 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81201.1 - 2.4e-151 502.0 12.7 3e-151 501.6 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX81201.1 - 0.39 11.4 3.6 0.7 10.5 0.1 3.1 2 2 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX81202.1 - 3.3e-103 344.4 5.6 3.8e-103 344.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX81203.1 - 4.5e-05 23.0 4.6 4.7e-05 23.0 3.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX81203.1 - 0.0026 17.8 1.2 0.0045 17.0 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX81203.1 - 0.038 14.3 1.6 0.091 13.1 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX81203.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 T5orf172 PF10544.9 EAX81204.1 - 3.4e-05 24.3 0.4 0.00012 22.5 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81204.1 - 0.0087 15.6 0.2 0.94 9.0 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX81204.1 - 0.016 15.1 0.1 0.14 12.0 0.0 2.4 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX81205.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81205.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81205.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81205.1 - 0.00011 22.2 2.7 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81205.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81205.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81205.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81205.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX81205.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX81205.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81205.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81205.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81205.1 - 0.3 11.4 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX81206.1 - 8.2e-33 112.6 0.6 2.1e-32 111.3 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX81206.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Trypan_PARP PF05887.11 EAX81208.1 - 0.084 12.8 9.3 0.13 12.2 9.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81208.1 - 1.9 8.9 4.8 2.7 8.5 4.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81209.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81209.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX81210.1 - 5.3e-146 484.5 12.6 6.2e-146 484.3 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81210.1 - 0.42 11.1 2.9 1.2 9.6 0.2 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX81211.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX81212.1 - 2.9e-05 24.6 0.3 7.3e-05 23.3 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81212.1 - 0.011 15.6 0.2 0.053 13.4 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX81212.1 - 0.016 14.7 1.0 0.13 11.7 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81213.1 - 7.8e-79 264.5 9.6 1e-78 264.1 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX81215.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX81216.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX81217.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX81217.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX81217.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain PTR PF12789.7 EAX81219.1 - 8.8e-60 198.7 40.7 4.1e-31 106.8 15.9 4.3 2 2 2 4 4 4 2 Phage tail repeat like DUF4795 PF16043.5 EAX81219.1 - 0.25 10.9 8.2 0.46 10.0 6.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4404 PF14357.6 EAX81219.1 - 6.8 7.4 7.0 11 6.8 0.3 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) DUF3839 PF12943.7 EAX81220.1 - 4e-158 524.2 13.5 4.8e-158 523.9 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81220.1 - 0.21 11.4 1.6 0.64 9.9 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81220.1 - 0.56 10.7 7.0 1.7 9.1 0.9 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81220.1 - 1.4 9.3 5.9 11 6.4 0.1 3.8 4 2 1 5 5 5 0 Tup N-terminal PRD PF00874.20 EAX81220.1 - 8.1 6.8 8.0 1.2 9.5 0.1 3.2 5 0 0 5 5 5 0 PRD domain DUF4107 PF13389.6 EAX81221.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81222.1 - 2.2e-153 508.6 14.5 2.8e-153 508.3 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81222.1 - 0.15 11.9 1.1 0.39 10.6 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX81222.1 - 0.24 12.0 3.0 4.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX81222.1 - 0.29 11.4 4.8 2.2 8.6 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX81222.1 - 3.8 8.0 6.5 4.2 7.9 0.3 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX81225.1 - 5.2e-37 128.1 27.8 6e-37 127.9 27.8 1.0 1 0 0 1 1 1 1 Glycine rich protein PTR PF12789.7 EAX81226.1 - 8.6e-09 35.3 10.6 8.3e-08 32.2 5.4 5.3 6 0 0 6 6 6 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX81226.1 - 0.00056 20.1 0.1 0.17 12.1 0.0 2.3 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain EMP24_GP25L PF01105.24 EAX81226.1 - 0.083 12.8 6.0 14 5.6 1.5 3.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD IL2 PF00715.17 EAX81226.1 - 0.33 10.9 3.6 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Interleukin 2 XPG_I PF00867.18 EAX81227.1 - 1.8e-27 95.5 0.3 4.7e-27 94.2 0.3 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAX81227.1 - 1.1e-19 70.8 0.0 2.9e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EAX81227.1 - 1.3e-07 32.1 0.2 3.8e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EAX81227.1 - 0.039 14.1 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif M16C_assoc PF08367.11 EAX81227.1 - 0.073 12.2 1.3 0.12 11.5 1.3 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DUF1493 PF07377.12 EAX81230.1 - 0.041 14.3 0.6 0.088 13.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX81231.1 - 1.4e-77 260.4 9.7 1.7e-77 260.2 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX81231.1 - 0.052 13.8 0.8 0.16 12.3 0.1 2.1 3 0 0 3 3 3 0 PRD domain DUF4107 PF13389.6 EAX81232.1 - 6e-59 198.8 1.6 6.9e-59 198.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81232.1 - 0.076 13.4 0.1 0.092 13.1 0.1 1.1 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PapD_N PF00345.20 EAX81235.1 - 0.022 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX81235.1 - 0.039 14.0 0.3 0.053 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX81235.1 - 0.064 13.3 0.2 0.079 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX81236.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX81236.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX81236.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain GPS2_interact PF15784.5 EAX81237.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81237.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Methyltransf_3 PF01596.17 EAX81239.1 - 0.39 9.8 2.0 0.65 9.1 0.1 2.3 2 1 1 3 3 3 0 O-methyltransferase T5orf172 PF10544.9 EAX81240.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX81242.1 - 6.8e-60 201.1 8.9 7.6e-60 201.0 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX81244.1 - 5.3e-62 208.0 5.1 5.9e-62 207.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PAXIP1_C PF15364.6 EAX81245.1 - 0.14 12.4 10.4 0.19 12.0 10.4 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2897 PF11446.8 EAX81245.1 - 0.64 9.9 5.0 1.5 8.8 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX81246.1 - 2.7e-07 30.3 2.8 4e-07 29.8 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81246.1 - 0.0051 16.5 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81246.1 - 0.05 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81246.1 - 0.062 13.0 0.1 0.27 11.0 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81246.1 - 0.067 12.9 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81246.1 - 0.2 11.6 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX81246.1 - 0.25 11.7 3.1 2.3 8.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX81246.1 - 0.28 11.4 7.4 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX81247.1 - 1.4e-103 345.6 7.2 1.5e-103 345.4 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX81248.1 - 1.3e-76 257.3 10.1 1.6e-76 256.9 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ARA70 PF12489.8 EAX81249.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3839 PF12943.7 EAX81250.1 - 4.4e-147 488.0 12.0 5.5e-147 487.7 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81250.1 - 4.7 7.7 6.7 3 8.4 0.6 3.2 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX81251.1 - 8e-72 240.7 3.7 9.5e-72 240.4 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX81251.1 - 0.17 10.2 0.8 0.23 9.8 0.8 1.1 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX81253.1 - 1.3e-143 476.7 15.2 1.5e-143 476.4 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81253.1 - 0.059 13.6 0.9 4 7.8 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain DUF5398 PF17376.2 EAX81253.1 - 0.97 10.1 0.1 0.97 10.1 0.1 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX81253.1 - 3.7 8.1 6.6 1.9 9.0 0.6 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81254.1 - 9.3e-158 523.0 13.0 1.2e-157 522.6 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81254.1 - 0.019 15.4 2.4 0.064 13.7 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81254.1 - 0.48 10.9 6.5 2 8.9 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81254.1 - 0.62 10.4 5.7 11 6.4 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX81254.1 - 1.2 9.7 6.6 0.26 11.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 EAX81255.1 - 0.037 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81255.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81255.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family GPS2_interact PF15784.5 EAX81256.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81256.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDE_1 PF03184.19 EAX81257.1 - 2.4e-16 59.9 0.0 4.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease KilA-N PF04383.13 EAX81258.1 - 4.8e-19 68.3 0.8 1.1e-18 67.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81258.1 - 0.0052 17.4 0.1 0.013 16.2 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family FPN1 PF06963.12 EAX81258.1 - 0.36 9.3 0.1 0.45 9.0 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX81259.1 - 6.9e-07 29.0 2.6 6.9e-07 29.0 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81259.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81259.1 - 6.1e-05 22.8 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81259.1 - 0.00018 21.5 3.3 0.00044 20.3 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81259.1 - 0.00062 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81259.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81259.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81259.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81259.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81259.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81259.1 - 0.094 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4107 PF13389.6 EAX81261.1 - 3.5e-73 245.1 4.0 4.2e-73 244.8 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX81261.1 - 0.19 10.1 0.9 0.27 9.6 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX81262.1 - 0.021 14.7 1.4 0.035 14.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) P22_AR_C PF10548.9 EAX81263.1 - 0.082 13.1 0.3 17 5.6 0.0 2.5 3 0 0 3 3 3 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX81263.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of Caskin AgrB PF04647.15 EAX81265.1 - 0.029 13.7 1.7 0.051 12.9 1.7 1.3 1 0 0 1 1 1 0 Accessory gene regulator B Podoplanin PF05808.11 EAX81265.1 - 0.029 14.5 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Orf78 PF06024.12 EAX81265.1 - 0.08 13.2 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 Orf78 (ac78) UL45 PF05473.12 EAX81265.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4690 PF15756.5 EAX81265.1 - 0.14 12.8 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Syndecan PF01034.20 EAX81265.1 - 0.55 10.2 2.2 0.96 9.4 0.4 2.2 2 0 0 2 2 2 0 Syndecan domain KilA-N PF04383.13 EAX81266.1 - 6.6e-21 74.3 0.0 7.2e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 KilA-N domain EpuA PF11772.8 EAX81267.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX81267.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.2 4 0 0 4 4 4 0 Phage tail repeat like DUF2897 PF11446.8 EAX81268.1 - 0.21 11.5 2.1 0.36 10.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX81269.1 - 4e-63 211.6 6.7 4.5e-63 211.5 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Meiosis_expr PF15163.6 EAX81270.1 - 0.058 14.1 0.6 0.1 13.3 0.2 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX81270.1 - 0.17 11.7 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Trypan_PARP PF05887.11 EAX81271.1 - 0.017 15.1 8.5 0.02 14.9 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GvpK PF05121.12 EAX81273.1 - 0.51 10.4 4.0 4 7.6 0.0 2.4 2 0 0 2 2 2 0 Gas vesicle protein K Myb_DNA-binding PF00249.31 EAX81274.1 - 1.6e-24 85.8 6.4 5.1e-13 49.0 0.8 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX81274.1 - 6.3e-23 80.8 7.6 4.4e-16 58.9 1.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX81274.1 - 5.8e-07 29.3 1.5 0.00039 20.3 0.1 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX81274.1 - 7.3e-05 22.8 0.5 0.21 11.6 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_5 PF13873.6 EAX81274.1 - 0.1 12.7 12.1 7.6 6.7 0.7 4.2 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Histone_HNS PF00816.21 EAX81274.1 - 0.17 12.7 2.1 0.28 12.0 0.5 1.9 2 0 0 2 2 2 0 H-NS histone family SANT_DAMP1_like PF16282.5 EAX81274.1 - 0.24 11.6 2.4 19 5.5 1.1 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF4108 PF13390.6 EAX81275.1 - 3.6e-72 240.9 11.9 4.1e-72 240.8 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4116 PF13475.6 EAX81276.1 - 0.068 12.9 0.8 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX81276.1 - 0.11 13.1 5.1 1.1 9.8 0.3 3.1 2 1 1 3 3 3 0 YmaF family PTR PF12789.7 EAX81276.1 - 0.34 11.0 0.2 0.34 11.0 0.2 5.2 5 1 1 6 6 6 0 Phage tail repeat like Phage_fiber PF03335.13 EAX81276.1 - 6.1 7.3 17.6 5.9 7.4 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX81277.1 - 0.0085 16.6 0.6 0.016 15.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX81278.1 - 7.3e-73 244.1 3.0 9.5e-73 243.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX81279.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX81282.1 - 8.7e-157 519.8 14.2 1.1e-156 519.5 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81282.1 - 0.09 13.1 0.3 2.1 8.7 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX81282.1 - 0.14 12.0 1.3 0.44 10.4 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81282.1 - 0.57 10.7 6.9 2.3 8.8 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX81283.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX81283.1 - 0.17 11.8 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX81285.1 - 9.5e-153 506.6 15.8 1.2e-152 506.2 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81285.1 - 0.2 12.0 6.4 0.39 11.0 0.1 3.5 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX81285.1 - 0.23 11.9 6.1 2 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81285.1 - 2.4 8.7 6.3 0.88 10.1 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX81287.1 - 7.2e-154 510.2 13.1 9e-154 509.9 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX81287.1 - 0.11 12.8 0.8 0.5 10.7 0.1 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX81287.1 - 3.6 8.1 6.3 4.7 7.7 0.1 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3781 PF12636.7 EAX81288.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Transposase_mut PF00872.18 EAX81289.1 - 0.0032 16.4 0.6 0.0047 15.8 0.4 1.4 1 1 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX81289.1 - 0.025 14.6 0.3 0.041 13.9 0.3 1.3 1 0 0 1 1 1 0 Vta1 like KilA-N PF04383.13 EAX81290.1 - 3.9e-06 26.7 0.2 3.9e-06 26.7 0.2 2.2 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81290.1 - 0.0052 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX81291.1 - 2.2e-07 30.6 2.8 2.2e-07 30.6 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81291.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81291.1 - 4.8e-05 23.2 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81291.1 - 0.00014 21.9 3.1 0.00033 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81291.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81291.1 - 0.0016 18.3 0.8 0.003 17.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81291.1 - 0.002 17.8 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81291.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX81291.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81291.1 - 0.082 13.3 0.1 0.74 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81291.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81291.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX81292.1 - 2.9e-156 518.0 12.6 3.7e-156 517.7 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81292.1 - 0.12 12.2 0.9 0.35 10.7 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase YmgB PF10798.8 EAX81296.1 - 0.012 15.4 0.2 0.027 14.3 0.2 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR PTR PF12789.7 EAX81297.1 - 6e-105 343.3 79.2 4e-31 106.9 14.7 6.8 3 2 3 6 6 6 4 Phage tail repeat like Cor1 PF04803.12 EAX81297.1 - 0.12 12.6 5.1 1.3 9.3 0.7 2.8 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region AviRa PF11599.8 EAX81297.1 - 2.3 7.6 7.5 1.7 8.0 0.7 2.7 1 1 2 3 3 3 0 RRNA methyltransferase AviRa DUF2785 PF10978.8 EAX81297.1 - 3.3 7.4 7.8 5.3 6.8 4.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) PAN_3 PF08277.12 EAX81298.1 - 0.025 14.4 1.7 0.097 12.5 1.7 2.0 1 0 0 1 1 1 0 PAN-like domain DUF4624 PF15417.6 EAX81298.1 - 0.12 12.2 2.0 0.46 10.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4624) Pox_A32 PF04665.12 EAX81299.1 - 1.1e-07 31.5 1.1 1.3e-07 31.4 1.1 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX81299.1 - 0.01 14.7 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Rad10 PF03834.14 EAX81299.1 - 0.02 14.9 0.4 0.047 13.7 0.3 1.7 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Zot PF05707.12 EAX81299.1 - 0.028 14.0 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) I-set PF07679.16 EAX81300.1 - 0.00014 21.9 0.5 0.0092 16.0 0.1 3.2 1 1 1 2 2 2 1 Immunoglobulin I-set domain CBM_4_9 PF02018.17 EAX81300.1 - 0.00038 20.7 0.1 0.00038 20.7 0.1 3.1 2 1 1 3 3 3 1 Carbohydrate binding domain TMEM154 PF15102.6 EAX81300.1 - 0.0015 18.5 0.7 0.005 16.7 0.3 2.1 2 1 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 EAX81300.1 - 0.012 15.9 0.6 0.045 14.1 0.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) PBP PF01161.20 EAX81300.1 - 0.054 13.8 0.1 11 6.4 0.0 2.5 1 1 1 2 2 2 0 Phosphatidylethanolamine-binding protein Matrilin_ccoil PF10393.9 EAX81300.1 - 0.11 12.4 0.4 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1676 PF07898.13 EAX81300.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Afi1 PF07792.12 EAX81300.1 - 0.43 11.1 9.8 0.094 13.2 1.2 2.8 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking IPK PF03770.16 EAX81301.1 - 1.9e-35 122.5 0.0 2.9e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase T5orf172 PF10544.9 EAX81302.1 - 5e-05 23.8 0.2 0.00013 22.4 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81302.1 - 0.021 14.4 0.1 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain Amidase02_C PF12123.8 EAX81303.1 - 0.0014 18.2 0.0 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX81304.1 - 5.6e-59 198.9 1.4 7.4e-59 198.5 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81304.1 - 0.14 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta P22_AR_C PF10548.9 EAX81306.1 - 0.084 13.1 0.2 21 5.4 0.1 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain Caskin-tail PF16632.5 EAX81306.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin PTR PF12789.7 EAX81307.1 - 6.3e-27 93.4 15.1 6.3e-27 93.4 15.1 3.5 3 0 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX81307.1 - 0.039 13.7 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PapD_N PF00345.20 EAX81308.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX81308.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX81309.1 - 0.054 13.9 0.4 0.063 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF4107 PF13389.6 EAX81312.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ABC_tran PF00005.27 EAX81314.1 - 1e-29 103.8 0.0 1.4e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX81314.1 - 2.3e-13 50.6 0.4 1.1e-05 25.4 0.8 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX81314.1 - 6.2e-07 29.1 0.4 1.3e-06 28.1 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX81314.1 - 1.8e-06 27.6 0.5 0.00068 19.1 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAX81314.1 - 3.3e-06 27.8 0.1 4.7e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAX81314.1 - 4.6e-06 26.6 0.2 7e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX81314.1 - 0.00016 21.6 0.1 0.00027 20.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EAX81314.1 - 0.0016 18.0 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EAX81314.1 - 0.0044 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_27 PF13514.6 EAX81314.1 - 0.0056 16.3 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAX81314.1 - 0.0063 16.6 0.2 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX81314.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EAX81314.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain T2SSE PF00437.20 EAX81314.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EAX81314.1 - 0.022 15.1 0.1 0.049 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX81314.1 - 0.024 14.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 EAX81314.1 - 0.026 14.1 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2813 PF11398.8 EAX81314.1 - 0.032 13.5 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) SbcCD_C PF13558.6 EAX81314.1 - 0.062 13.5 0.0 1.2 9.4 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EAX81314.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EAX81314.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAX81314.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EAX81314.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAX81314.1 - 0.17 11.9 0.2 0.31 11.1 0.2 1.4 1 0 0 1 1 1 0 Dynamin family FAS_N PF17828.1 EAX81315.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX81315.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX81316.1 - 0.03 14.7 1.0 0.033 14.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX81316.1 - 2 7.3 4.2 2.2 7.2 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX81316.1 - 3.8 8.2 6.7 8.1 7.1 6.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX81316.1 - 5.9 6.9 7.6 6.7 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Trypan_PARP PF05887.11 EAX81319.1 - 0.11 12.5 8.6 0.17 11.9 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81319.1 - 2.2 8.7 6.3 3.1 8.2 6.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81320.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81320.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81321.1 - 0.12 12.4 5.1 0.18 11.8 5.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX81322.1 - 2.1e-137 456.3 8.8 2.4e-137 456.1 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81322.1 - 0.041 13.4 0.6 0.075 12.5 0.3 1.5 1 1 1 2 2 2 0 Z1 domain KELK PF15796.5 EAX81322.1 - 0.2 12.2 1.1 0.73 10.3 0.7 2.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF257 PF03192.13 EAX81323.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX81323.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A32 PF04665.12 EAX81325.1 - 4.2e-07 29.7 0.0 7.7e-07 28.8 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX81326.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX81328.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase GPS2_interact PF15784.5 EAX81329.1 - 0.047 14.1 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX81330.1 - 8e-05 22.2 0.4 8.7e-05 22.1 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX81331.1 - 5e-33 113.3 0.8 9.3e-33 112.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81332.1 - 8.4e-07 29.5 0.2 1.6e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX81333.1 - 9.6e-59 195.3 36.2 1.8e-32 111.2 12.3 5.8 3 2 2 5 5 5 3 Phage tail repeat like PBP5_C PF07943.13 EAX81333.1 - 0.046 14.0 0.2 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DUF1493 PF07377.12 EAX81334.1 - 0.025 15.1 1.3 0.034 14.6 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX81334.1 - 0.17 11.9 3.8 4.2 7.5 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX81335.1 - 3e-27 95.6 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX81335.1 - 0.14 12.7 1.1 0.88 10.1 0.2 2.0 1 1 0 2 2 2 0 Cell division protein ZapB APC_u14 PF16635.5 EAX81335.1 - 0.21 12.1 2.2 0.29 11.7 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DUF3839 PF12943.7 EAX81336.1 - 9.4e-76 254.4 4.8 1.1e-75 254.2 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81336.1 - 0.016 14.7 0.3 0.018 14.5 0.3 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX81336.1 - 0.091 13.4 1.7 0.18 12.4 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Gly-zipper_Omp PF13488.6 EAX81338.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX81338.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX81338.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif KilA-N PF04383.13 EAX81339.1 - 1e-42 144.5 0.5 2.2e-42 143.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81339.1 - 0.0067 17.0 0.1 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX81340.1 - 6.6e-08 32.3 1.2 7.9e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81340.1 - 0.0048 16.6 0.1 0.0053 16.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81340.1 - 0.06 13.1 0.0 0.094 12.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81340.1 - 0.074 13.0 0.4 0.65 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) SEO_C PF14577.6 EAX81341.1 - 0.047 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PadR PF03551.14 EAX81343.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX81344.1 - 0.017 15.6 0.5 0.022 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX81344.1 - 1.4 8.9 5.6 1.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Amidase02_C PF12123.8 EAX81346.1 - 0.0086 15.7 0.1 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX81347.1 - 3.9e-35 120.1 0.2 3.9e-35 120.1 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81347.1 - 0.019 15.1 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX81347.1 - 1.7 9.2 8.4 5.7 7.5 3.9 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX81348.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81348.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81348.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81348.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX81349.1 - 1.7e-156 518.8 13.7 2.2e-156 518.5 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX81349.1 - 0.099 13.2 4.3 0.29 11.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX81349.1 - 0.24 11.7 2.3 0.62 10.4 0.9 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX81349.1 - 0.98 9.9 7.0 5.7 7.5 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX81350.1 - 0.3 11.1 9.4 0.46 10.5 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX81350.1 - 2.7 5.5 13.0 3.4 5.2 13.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX81350.1 - 8.4 6.8 7.3 12 6.3 7.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81351.1 - 0.046 14.2 0.5 0.055 13.9 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81351.1 - 0.059 12.3 0.1 0.059 12.3 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX81352.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein T5orf172 PF10544.9 EAX81353.1 - 7.8e-07 29.6 0.2 1.9e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81353.1 - 0.0099 15.7 0.2 0.06 13.2 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX81353.1 - 0.011 15.3 0.6 0.12 11.9 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Trypan_PARP PF05887.11 EAX81355.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81355.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81356.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81356.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX81357.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein LBR_tudor PF09465.10 EAX81358.1 - 0.00053 19.7 0.3 0.00098 18.9 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX81358.1 - 0.034 14.6 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor DUF3839 PF12943.7 EAX81359.1 - 3.7e-145 481.7 10.1 4.3e-145 481.5 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX81359.1 - 0.08 13.6 0.8 0.36 11.5 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5398) HSCB_C PF07743.13 EAX81360.1 - 0.045 14.2 0.1 0.048 14.2 0.1 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF5446 PF17522.2 EAX81360.1 - 0.067 13.4 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX81361.1 - 3.7e-157 521.0 12.9 4.6e-157 520.7 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81361.1 - 0.23 11.9 2.9 0.18 12.2 0.5 1.8 2 0 0 2 2 2 0 Fez1 DUF1689 PF07954.11 EAX81361.1 - 0.39 11.1 3.3 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) KELK PF15796.5 EAX81361.1 - 0.62 10.6 5.1 5.2 7.6 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81362.1 - 4.3e-159 527.3 14.9 5.5e-159 527.0 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81362.1 - 2.4 8.7 7.7 2.5 8.6 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX81364.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX81364.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX81365.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX81365.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_MLP1_2 PF07926.12 EAX81366.1 - 0.015 15.3 0.4 0.019 15.0 0.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81366.1 - 0.061 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81366.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4378 PF14309.6 EAX81367.1 - 0.036 14.5 0.0 0.079 13.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) DUF4106 PF13388.6 EAX81368.1 - 4.1e-117 392.0 23.5 4.1e-117 392.0 23.5 2.1 2 2 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3112 PF11309.8 EAX81368.1 - 0.12 11.8 0.3 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) SLIDE PF09111.10 EAX81368.1 - 0.21 11.6 3.3 3.4 7.7 0.2 2.7 2 0 0 2 2 2 0 SLIDE DUF3839 PF12943.7 EAX81369.1 - 6.5e-40 137.1 3.8 9.4e-40 136.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX81369.1 - 0.064 12.4 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II TetR_C_34 PF17929.1 EAX81372.1 - 0.018 15.1 0.0 0.36 10.9 0.0 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3461 PF11944.8 EAX81372.1 - 0.046 13.9 9.9 0.84 9.8 3.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) Fez1 PF06818.15 EAX81372.1 - 0.11 12.9 12.6 0.35 11.3 7.2 2.5 3 0 0 3 3 3 0 Fez1 AATF-Che1 PF13339.6 EAX81372.1 - 5.9 7.6 18.1 0.8 10.4 5.4 3.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor NACHT_N PF17100.5 EAX81372.1 - 8.2 6.2 11.0 0.53 10.1 4.5 2.3 3 0 0 3 3 3 0 N-terminal domain of NWD NACHT-NTPase TMPIT PF07851.13 EAX81372.1 - 9 5.4 11.1 25 4.0 5.9 2.8 3 0 0 3 3 3 0 TMPIT-like protein CHDCT2 PF08074.11 EAX81372.1 - 9.1 6.4 12.4 3.1 7.9 3.6 3.0 2 1 0 3 3 3 0 CHDCT2 (NUC038) domain Ank_2 PF12796.7 EAX81373.1 - 2.6e-118 386.8 56.3 5.4e-19 68.6 3.7 8.8 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAX81373.1 - 2.4e-91 296.5 40.4 1.4e-07 31.7 0.1 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 EAX81373.1 - 1.2e-89 293.2 41.4 3.1e-10 40.1 0.2 8.0 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX81373.1 - 3.1e-88 289.1 36.0 9.1e-10 38.9 0.2 12.5 2 1 11 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX81373.1 - 9.5e-73 231.5 27.3 2.9e-05 24.1 0.0 11.4 12 0 0 12 12 11 11 Ankyrin repeat DUF3447 PF11929.8 EAX81373.1 - 6.8e-15 54.8 2.9 2.6e-14 52.9 2.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX81373.1 - 1.7e-09 37.7 10.2 76 3.6 0.0 9.9 1 1 9 10 10 10 0 Protein of unknown function (DUF3718) B5 PF03484.15 EAX81373.1 - 1.5e-08 34.8 1.3 1e+02 3.3 0.0 9.4 2 2 8 10 10 10 0 tRNA synthetase B5 domain Mic1 PF07035.12 EAX81373.1 - 3.9e-08 33.1 2.7 0.47 10.2 0.0 6.7 3 1 5 8 8 8 1 Colon cancer-associated protein Mic1-like Phage_G PF02306.15 EAX81373.1 - 1.7e-05 24.6 14.3 6.2 6.5 0.1 6.9 1 1 8 9 9 9 1 Major spike protein (G protein) Imm53 PF15580.6 EAX81373.1 - 3.7e-05 23.3 35.5 16 5.3 0.2 9.5 1 1 8 9 9 9 0 Immunity protein 53 DUF503 PF04456.12 EAX81373.1 - 0.00016 21.5 14.1 98 2.9 0.0 8.2 2 2 7 9 9 9 0 Protein of unknown function (DUF503) DUF5623 PF18536.1 EAX81375.1 - 0.082 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX81375.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX81376.1 - 1.5e-34 119.7 14.1 7.4e-34 117.4 14.1 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX81376.1 - 0.02 14.2 0.4 0.034 13.5 0.4 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5106 PF17127.4 EAX81376.1 - 0.047 14.0 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) Lac_bphage_repr PF06543.12 EAX81376.1 - 0.14 12.2 0.1 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Pox_A32 PF04665.12 EAX81377.1 - 3.8e-07 29.8 2.3 3.8e-07 29.8 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81377.1 - 3.3e-05 24.2 0.2 0.00025 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81377.1 - 5.2e-05 23.0 0.3 0.45 10.2 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81377.1 - 0.00015 21.8 3.1 0.00032 20.8 3.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81377.1 - 0.00053 19.8 0.1 0.0012 18.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX81377.1 - 0.00086 19.0 0.6 0.0059 16.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX81377.1 - 0.0013 18.5 0.5 0.0027 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81377.1 - 0.0085 16.4 0.0 0.026 14.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX81377.1 - 0.076 13.4 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX81377.1 - 0.077 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX81377.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81377.1 - 0.42 10.9 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX81378.1 - 4.8e-56 188.7 4.0 5.3e-56 188.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX81379.1 - 2.7e-05 24.2 0.4 4.3e-05 23.6 0.4 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX81379.1 - 0.00032 21.0 0.0 0.00048 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX81379.1 - 0.00035 20.4 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81379.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81379.1 - 0.019 15.3 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX81379.1 - 0.034 13.6 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX81379.1 - 0.056 13.1 0.2 0.12 12.0 0.0 1.5 1 1 0 2 2 2 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX81379.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX81379.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX81381.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX81382.1 - 3.8e-05 24.1 2.5 0.00021 21.7 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX81382.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4108 PF13390.6 EAX81383.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX81385.1 - 4.6e-05 23.5 2.0 8.1e-05 22.7 2.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX81385.1 - 8.3e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX81385.1 - 0.00029 20.7 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81385.1 - 0.00097 19.0 0.4 0.0022 17.8 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81385.1 - 0.0074 16.6 0.0 0.0099 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX81385.1 - 0.044 13.2 0.1 0.058 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX81385.1 - 0.075 12.7 0.4 0.16 11.6 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX81385.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81385.1 - 0.1 12.4 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX81385.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX81385.1 - 0.51 10.8 3.5 0.29 11.6 0.6 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF1827 PF08860.10 EAX81385.1 - 1.4 9.2 4.7 4.8 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX81386.1 - 8e-123 408.6 14.1 1.1e-122 408.1 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81386.1 - 0.042 14.1 0.6 9.6 6.6 0.0 2.9 2 1 0 2 2 2 0 Rx N-terminal domain PRD PF00874.20 EAX81386.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.7 3 1 0 3 3 3 0 PRD domain HTH_7 PF02796.15 EAX81387.1 - 0.00041 20.4 0.2 0.00075 19.5 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EAX81387.1 - 0.00093 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EAX81387.1 - 0.0032 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Phage_AlpA PF05930.12 EAX81387.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) ResIII PF04851.15 EAX81388.1 - 3.5e-05 23.9 1.8 6e-05 23.1 1.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81388.1 - 0.00029 20.7 0.1 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX81388.1 - 0.00029 21.1 0.0 0.00046 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX81388.1 - 0.0015 18.4 0.6 0.0034 17.2 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81388.1 - 0.0085 16.4 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX81388.1 - 0.043 13.3 0.1 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX81388.1 - 0.062 13.1 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX81388.1 - 0.064 12.9 0.5 0.11 12.2 0.2 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX81388.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX81388.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX81388.1 - 0.2 11.4 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX81388.1 - 0.43 11.0 3.7 0.22 11.9 0.7 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3839 PF12943.7 EAX81389.1 - 2.1e-155 515.2 14.0 2.7e-155 514.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81389.1 - 0.8 10.2 8.2 3.1 8.3 1.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81389.1 - 1.6 9.3 6.5 1.4 9.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX81390.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) SOG2 PF10428.9 EAX81391.1 - 0.28 10.3 27.9 0.32 10.1 27.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L6 PF00347.23 EAX81392.1 - 4.7e-10 40.0 0.7 0.00037 21.1 0.0 3.1 2 1 1 3 3 3 3 Ribosomal protein L6 DUF3839 PF12943.7 EAX81393.1 - 8.8e-156 516.5 12.0 1.1e-155 516.2 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81393.1 - 0.022 15.0 0.8 2.5 8.4 0.1 3.4 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX81393.1 - 0.28 11.6 5.2 2 8.9 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX81394.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF5065 PF16723.5 EAX81396.1 - 0.02 15.0 1.5 0.91 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX81397.1 - 6.7e-157 520.1 13.2 8e-157 519.9 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX81397.1 - 0.12 11.9 0.2 0.5 9.8 0.1 2.1 1 1 0 1 1 1 0 SLOG cluster2 Rx_N PF18052.1 EAX81397.1 - 0.69 10.2 2.9 3 8.2 0.0 2.9 2 2 1 3 3 3 0 Rx N-terminal domain Podoplanin PF05808.11 EAX81399.1 - 0.019 15.0 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Podoplanin AgrB PF04647.15 EAX81399.1 - 0.023 14.0 1.7 0.037 13.3 1.7 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Orf78 PF06024.12 EAX81399.1 - 0.056 13.8 0.1 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF4690 PF15756.5 EAX81399.1 - 0.094 13.3 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage UL45 PF05473.12 EAX81399.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Amnionless PF14828.6 EAX81399.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 EAX81399.1 - 0.3 11.1 1.7 0.69 9.9 0.4 2.1 2 0 0 2 2 2 0 Syndecan domain Glyco_transf_8 PF01501.20 EAX81400.1 - 1.4e-13 51.0 5.6 2.2e-13 50.4 5.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF3839 PF12943.7 EAX81401.1 - 4.9e-152 504.2 10.8 5.6e-152 504.0 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81401.1 - 0.11 12.3 0.8 0.38 10.6 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81401.1 - 2.8 8.4 6.2 3 8.4 0.4 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Meiosis_expr PF15163.6 EAX81402.1 - 0.0089 16.7 1.2 0.012 16.2 0.5 1.6 2 0 0 2 2 2 1 Meiosis-expressed DUF4108 PF13390.6 EAX81403.1 - 1.4e-63 213.1 6.0 1.6e-63 212.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX81405.1 - 2.1e-120 400.6 12.9 2.6e-120 400.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81405.1 - 0.013 15.9 0.7 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Aminotran_1_2 PF00155.21 EAX81405.1 - 0.086 12.0 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2408 PF10303.9 EAX81405.1 - 0.096 13.3 0.6 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX81406.1 - 3.6e-06 27.5 0.2 9.8e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81406.1 - 0.021 14.4 0.4 0.28 10.7 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Beta_helix PF13229.6 EAX81408.1 - 3.2e-22 79.1 38.9 3.2e-14 53.1 15.8 2.8 2 1 1 3 3 3 2 Right handed beta helix region Pectate_lyase_3 PF12708.7 EAX81408.1 - 0.0007 19.5 11.7 0.034 14.0 3.4 2.7 2 1 0 2 2 2 2 Pectate lyase superfamily protein TMEM154 PF15102.6 EAX81408.1 - 0.011 15.6 1.3 0.02 14.8 1.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4957 PF16318.5 EAX81408.1 - 0.048 13.6 11.6 0.18 11.7 5.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4957) ECSCR PF15820.5 EAX81408.1 - 0.058 13.2 1.6 0.13 12.1 1.6 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ASFV_J13L PF05568.11 EAX81408.1 - 3 7.5 6.2 4.6 6.9 6.2 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3781 PF12636.7 EAX81409.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX81410.1 - 2.2e-158 525.0 14.4 2.8e-158 524.7 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81410.1 - 0.02 15.4 1.4 0.1 13.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX81410.1 - 0.19 11.5 1.7 0.47 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase P4Ha_N PF08336.11 EAX81410.1 - 0.62 10.1 5.2 7.3 6.6 0.0 2.9 2 2 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KELK PF15796.5 EAX81410.1 - 0.62 10.5 7.9 2.4 8.6 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81411.1 - 5.1e-150 497.6 11.0 6.8e-150 497.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81411.1 - 0.0043 17.5 0.8 0.039 14.4 0.1 2.1 2 0 0 2 2 2 1 Fez1 GCN5L1 PF06320.13 EAX81411.1 - 0.025 14.7 0.3 0.8 9.9 0.0 3.1 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) MitMem_reg PF13012.6 EAX81411.1 - 0.093 13.2 0.6 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81411.1 - 0.3 11.6 4.6 2.1 8.9 0.6 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DegS PF05384.11 EAX81411.1 - 0.36 10.3 3.8 0.17 11.3 0.7 2.0 2 0 0 2 2 2 0 Sensor protein DegS DUF5065 PF16723.5 EAX81413.1 - 0.56 10.3 3.8 13 5.8 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX81414.1 - 1.1e-156 519.4 14.0 1.4e-156 519.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81414.1 - 0.37 11.3 7.1 2.1 8.9 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81414.1 - 0.48 11.0 6.4 0.21 12.1 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) GST_N PF02798.20 EAX81415.1 - 0.027 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MULE PF10551.9 EAX81416.1 - 3.7e-12 46.5 0.1 5.9e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain Ank_2 PF12796.7 EAX81417.1 - 4.9e-52 174.5 23.0 1.7e-18 67.0 4.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX81417.1 - 1.5e-45 151.7 12.4 9.8e-10 38.4 0.0 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAX81417.1 - 9.7e-45 150.4 12.6 1.6e-12 47.7 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX81417.1 - 6.4e-42 141.1 15.0 8.2e-12 45.1 0.5 3.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX81417.1 - 5.2e-36 118.6 8.1 6.3e-07 29.2 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat ThiS-like PF14453.6 EAX81417.1 - 3.7e-06 26.9 5.9 9.8 6.3 0.0 5.1 1 1 4 5 5 5 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX81417.1 - 0.00061 20.0 0.0 0.21 11.9 0.0 2.9 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase Phage_G PF02306.15 EAX81417.1 - 0.0075 16.0 1.6 13 5.4 0.1 3.2 1 1 2 3 3 3 2 Major spike protein (G protein) PH_8 PF15409.6 EAX81417.1 - 0.017 15.4 0.5 67 3.9 0.0 4.0 1 1 4 5 5 5 0 Pleckstrin homology domain AbrB_C PF18277.1 EAX81417.1 - 1.4 8.6 5.0 2.1e+02 1.6 0.0 4.4 5 0 0 5 5 5 0 AbrB C-terminal domain Ank PF00023.30 EAX81418.1 - 2.7e-83 271.1 19.3 2.5e-09 37.2 0.0 9.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 EAX81418.1 - 2.7e-78 257.4 23.3 5.1e-13 49.2 0.0 9.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX81418.1 - 6.5e-77 252.6 34.8 2.7e-12 46.6 0.2 6.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX81418.1 - 3.8e-75 248.5 32.8 2.2e-14 53.8 0.7 7.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX81418.1 - 1.5e-67 215.5 14.8 1.6e-06 28.0 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat ThiS-like PF14453.6 EAX81418.1 - 1.6e-09 37.6 13.2 2.8 8.0 0.0 8.8 1 1 8 9 9 9 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX81418.1 - 2.3e-06 27.8 0.0 0.96 9.8 0.0 5.0 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase LolA PF03548.15 EAX81418.1 - 2.6e-06 27.3 0.5 0.65 9.7 0.1 4.2 3 1 0 4 4 4 1 Outer membrane lipoprotein carrier protein LolA Phage_G PF02306.15 EAX81418.1 - 8.6e-05 22.3 3.1 1.7 8.4 0.0 5.0 1 1 5 6 6 6 1 Major spike protein (G protein) PH_8 PF15409.6 EAX81418.1 - 0.00088 19.5 1.6 98 3.3 0.0 6.2 1 1 8 9 9 9 0 Pleckstrin homology domain CEP44 PF15007.6 EAX81418.1 - 0.0011 19.1 0.0 1.1e+02 2.9 0.0 6.0 2 2 5 8 8 8 0 Centrosomal spindle body, CEP44 AnkUBD PF18418.1 EAX81418.1 - 0.0031 17.6 0.0 30 4.9 0.0 3.5 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain Staphylokinase PF02821.16 EAX81418.1 - 0.0073 16.7 1.2 1.6e+02 2.7 0.0 5.4 1 1 7 8 8 8 0 Staphylokinase/Streptokinase family CCG PF02754.16 EAX81418.1 - 0.02 15.1 3.1 80 3.6 0.0 4.7 2 2 2 5 5 5 0 Cysteine-rich domain PUB_1 PF18486.1 EAX81418.1 - 0.049 13.5 0.3 97 2.9 0.0 3.7 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain GPI-anchored PF10342.9 EAX81418.1 - 0.22 12.3 1.4 26 5.7 0.1 4.1 2 2 3 6 6 6 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SIP PF04954.13 EAX81418.1 - 0.58 10.7 2.7 13 6.3 0.1 2.9 2 1 1 3 3 3 0 Siderophore-interacting protein Defensin_3 PF08131.11 EAX81418.1 - 1.3 9.3 4.4 99 3.2 0.1 3.8 3 0 0 3 3 3 0 Defensin-like peptide family 3Beta_HSD PF01073.19 EAX81418.1 - 3.7 6.5 9.6 10 5.0 0.1 4.3 3 1 1 5 5 5 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4108 PF13390.6 EAX81420.1 - 3.2e-53 179.5 7.8 3.6e-53 179.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX81421.1 - 7 6.4 5.9 7.3 6.3 5.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Xpo1 PF08389.12 EAX81422.1 - 0.075 13.1 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Exportin 1-like protein Laminin_EGF PF00053.24 EAX81422.1 - 5.3 7.3 10.9 9.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Laminin EGF domain DUF3839 PF12943.7 EAX81423.1 - 2.1e-154 512.0 12.2 2.7e-154 511.6 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX81423.1 - 0.51 11.3 2.5 1.3 10.0 0.4 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Glu-tRNAGln PF02686.15 EAX81423.1 - 5.4 7.4 6.3 0.9 9.9 1.1 2.4 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF4625 PF15418.6 EAX81424.1 - 5.4e-06 26.7 5.3 0.0071 16.6 0.0 4.1 3 2 0 3 3 3 2 Domain of unknown function (DUF4625) DUF4469 PF14734.6 EAX81424.1 - 0.044 13.9 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold Omp28 PF11551.8 EAX81424.1 - 0.053 13.4 0.1 0.51 10.2 0.0 2.5 3 0 0 3 3 3 0 Outer membrane protein Omp28 Amidase02_C PF12123.8 EAX81426.1 - 0.0089 15.7 0.1 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase S_layer_C PF05124.12 EAX81426.1 - 0.085 12.8 0.2 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 S-layer like family, C-terminal region DUF4107 PF13389.6 EAX81427.1 - 4.3e-72 241.6 3.6 5.6e-72 241.2 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81427.1 - 0.12 12.8 0.3 0.29 11.5 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX81428.1 - 5.3e-37 127.8 16.5 2.5e-36 125.6 16.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral TPR_MLP1_2 PF07926.12 EAX81429.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81429.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81429.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family FliJ PF02050.16 EAX81430.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX81431.1 - 2.9e-72 242.1 3.8 3.8e-72 241.7 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX81433.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ActA PF05058.12 EAX81434.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX81434.1 - 0.31 11.4 4.7 0.51 10.6 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX81434.1 - 1.9 8.6 6.5 1.5 9.0 5.0 1.6 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX81434.1 - 3 8.9 0.2 3 8.9 0.2 3.4 4 1 0 4 4 4 0 TMP repeat DUF3839 PF12943.7 EAX81435.1 - 9e-40 136.6 4.2 1.3e-39 136.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX81435.1 - 0.096 13.1 0.5 0.57 10.7 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB T5orf172 PF10544.9 EAX81436.1 - 1.7e-06 28.5 0.1 4.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81436.1 - 0.0042 16.6 0.8 0.08 12.5 0.2 2.0 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX81437.1 - 2.7e-38 130.3 0.7 3.4e-38 129.9 0.1 1.5 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81437.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX81437.1 - 0.25 9.9 0.1 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) T5orf172 PF10544.9 EAX81439.1 - 2.7e-06 27.8 0.2 7.6e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81439.1 - 0.013 15.4 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain E2F_TDP PF02319.20 EAX81440.1 - 3.5e-11 43.0 0.0 8.7e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF3839 PF12943.7 EAX81441.1 - 3.4e-67 226.4 2.2 3.8e-67 226.3 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81441.1 - 0.04 13.4 0.2 0.046 13.2 0.2 1.0 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX81441.1 - 0.093 13.4 1.6 0.8 10.4 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX81443.1 - 3e-45 154.3 2.2 4.2e-45 153.8 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX81445.1 - 3.6e-72 241.8 3.6 4.7e-72 241.4 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81445.1 - 0.022 15.1 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX81446.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase WD40 PF00400.32 EAX81447.1 - 2.5e-11 43.9 2.4 0.22 12.4 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX81447.1 - 2.9e-08 33.9 0.0 0.2 12.0 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX81447.1 - 0.00013 21.9 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.9 EAX81447.1 - 0.0012 17.6 0.0 0.0066 15.1 0.1 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 EAX81447.1 - 0.15 12.6 0.0 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Lactonase PF10282.9 EAX81447.1 - 0.15 11.3 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF4852 PF16144.5 EAX81449.1 - 0.029 14.5 0.2 0.067 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) DUF4107 PF13389.6 EAX81451.1 - 1.5e-70 236.6 3.2 2e-70 236.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81454.1 - 2.7e-149 495.2 12.1 4e-149 494.7 12.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX81454.1 - 0.0014 19.1 0.1 0.012 16.2 0.1 2.6 2 0 0 2 2 2 1 T5orf172 domain Fez1 PF06818.15 EAX81454.1 - 0.006 17.0 0.2 0.05 14.0 0.0 2.1 2 0 0 2 2 2 1 Fez1 Lectin_legB PF00139.19 EAX81454.1 - 0.031 13.8 0.4 2 7.9 0.1 2.2 2 0 0 2 2 2 0 Legume lectin domain KELK PF15796.5 EAX81454.1 - 0.46 11.0 3.7 3.1 8.3 0.4 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase F5_F8_type_C PF00754.25 EAX81456.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain RuBisCO_large_N PF02788.16 EAX81456.1 - 0.14 12.3 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF4107 PF13389.6 EAX81457.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81457.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TPR_MLP1_2 PF07926.12 EAX81458.1 - 0.0084 16.2 0.4 0.011 15.9 0.4 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81458.1 - 0.044 13.6 0.1 0.059 13.2 0.1 1.3 1 1 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81458.1 - 0.32 11.0 7.8 0.12 12.3 2.5 2.4 3 0 0 3 3 3 0 Spo12 family Pox_D5 PF03288.16 EAX81459.1 - 4.2e-05 23.9 2.4 0.0002 21.8 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like KilA-N PF04383.13 EAX81460.1 - 1.9e-34 117.9 0.6 3.7e-34 117.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81460.1 - 0.038 14.6 0.0 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX81460.1 - 0.13 13.0 1.6 11 6.8 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX81461.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81461.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81461.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81461.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DASH_Dam1 PF08653.10 EAX81462.1 - 0.095 12.5 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3839 PF12943.7 EAX81464.1 - 1.2e-156 519.3 13.2 1.5e-156 519.0 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81464.1 - 2 8.9 5.9 5 7.7 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81465.1 - 2.4e-148 492.1 12.2 3.1e-148 491.8 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX81465.1 - 0.011 16.1 0.7 0.87 10.0 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX81465.1 - 0.023 15.2 0.4 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX81465.1 - 0.14 12.7 3.5 1.1 9.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX81465.1 - 0.2 12.0 3.0 19 5.6 0.1 3.2 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX81465.1 - 0.99 9.9 6.5 2 8.9 1.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4168 PF13767.6 EAX81465.1 - 1.4 10.2 4.2 27 6.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF4107 PF13389.6 EAX81466.1 - 1e-65 220.9 12.6 5e-64 215.4 12.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX81467.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX81467.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81467.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF2897 PF11446.8 EAX81468.1 - 1.1 9.2 3.8 2.4 8.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GDE_C PF06202.14 EAX81469.1 - 0.11 11.5 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase KilA-N PF04383.13 EAX81470.1 - 2.4e-42 143.3 1.7 6.2e-42 142.0 0.2 2.4 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81470.1 - 0.0069 17.0 0.0 0.025 15.2 0.0 1.9 1 0 0 1 1 1 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX81470.1 - 0.58 10.4 2.7 2.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pox_A32 PF04665.12 EAX81471.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81471.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81471.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81471.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81471.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81471.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81471.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81471.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81471.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81471.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81471.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81471.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) P_proprotein PF01483.20 EAX81472.1 - 2.3e-08 33.9 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain LPD18 PF18832.1 EAX81472.1 - 0.14 12.3 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 Arc_C PF18162.1 EAX81472.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Arc C-lobe DUF1947 PF09183.10 EAX81473.1 - 0.019 15.3 0.3 0.096 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) TPR_MLP1_2 PF07926.12 EAX81474.1 - 0.055 13.5 0.1 0.076 13.1 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX81474.1 - 0.088 12.0 1.9 0.098 11.8 1.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX81474.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX81474.1 - 6.2 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family PTR PF12789.7 EAX81475.1 - 7.9e-12 45.1 31.2 2.2e-08 34.0 5.6 4.5 5 0 0 5 5 5 3 Phage tail repeat like EMP24_GP25L PF01105.24 EAX81475.1 - 6.8 6.6 9.2 2.2 8.2 1.6 3.2 3 1 1 4 4 4 0 emp24/gp25L/p24 family/GOLD T5orf172 PF10544.9 EAX81476.1 - 2.2e-06 28.1 0.4 7.2e-06 26.5 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81476.1 - 0.13 11.8 0.3 1.8 8.1 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81477.1 - 3.5e-79 265.7 10.7 4.7e-79 265.3 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX81477.1 - 0.031 14.5 0.3 0.075 13.3 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 PRD PF00874.20 EAX81477.1 - 0.1 12.9 1.2 0.42 10.9 0.1 2.4 3 0 0 3 3 3 0 PRD domain DUF4108 PF13390.6 EAX81480.1 - 4.6e-60 201.7 8.6 5.1e-60 201.5 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX81483.1 - 3.9e-157 520.9 12.1 4.8e-157 520.6 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81483.1 - 0.48 10.9 5.0 1.5 9.3 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81483.1 - 0.76 10.1 4.9 12 6.2 0.0 3.8 4 1 1 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX81484.1 - 1.5e-33 115.0 0.4 3.5e-33 113.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81486.1 - 6e-89 297.7 8.1 6.7e-89 297.5 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81486.1 - 0.031 13.8 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 Z1 domain MetOD2 PF18548.1 EAX81487.1 - 0.019 15.0 14.3 0.042 13.9 0.6 3.4 2 1 1 3 3 3 0 Metanogen output domain 2 Exonuc_VII_L PF02601.15 EAX81487.1 - 0.045 13.3 8.9 0.054 13.1 0.1 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAX81487.1 - 0.078 11.8 22.7 0.039 12.9 2.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NurA PF09376.10 EAX81487.1 - 0.4 10.3 4.5 0.54 9.9 0.1 2.1 1 1 1 2 2 2 0 NurA domain DivIVA PF05103.13 EAX81487.1 - 0.92 9.6 11.0 0.17 12.0 5.1 2.3 2 0 0 2 2 2 0 DivIVA protein Fez1 PF06818.15 EAX81487.1 - 1.2 9.5 23.6 2 8.8 8.7 2.4 1 1 1 2 2 2 0 Fez1 IFT20 PF14931.6 EAX81487.1 - 1.5 9.0 15.2 0.91 9.7 3.0 2.8 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Laminin_II PF06009.12 EAX81487.1 - 2.5 8.1 12.2 1.5 8.8 6.7 2.5 2 1 0 2 2 2 0 Laminin Domain II HR1 PF02185.16 EAX81487.1 - 3.6 7.8 15.6 0.6 10.3 8.4 3.2 3 1 0 3 3 3 0 Hr1 repeat TPR_MLP1_2 PF07926.12 EAX81487.1 - 6.6 6.8 23.9 0.039 14.0 3.9 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 EAX81487.1 - 7.3 4.4 8.3 0.24 9.3 0.4 2.0 2 1 0 3 3 3 0 Prominin DUF4108 PF13390.6 EAX81489.1 - 1.7e-71 238.8 11.5 1.9e-71 238.6 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAX81489.1 - 0.39 11.7 3.1 0.85 10.6 3.1 1.5 1 0 0 1 1 1 0 Deacetylase PdaC DUF4106 PF13388.6 EAX81490.1 - 3.1e-274 909.5 21.2 5.1e-274 908.8 21.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX81490.1 - 0.024 14.2 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein KAR PF15222.6 EAX81490.1 - 0.057 13.7 0.1 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated TFIIA PF03153.13 EAX81490.1 - 1 9.3 29.1 0.78 9.7 19.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit T5orf172 PF10544.9 EAX81491.1 - 4.2e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF1493 PF07377.12 EAX81493.1 - 0.035 14.6 0.7 0.071 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) IBD PF10416.9 EAX81496.1 - 6.4e-35 120.0 0.4 1.2e-34 119.1 0.1 1.5 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD GPS2_interact PF15784.5 EAX81497.1 - 0.039 14.4 0.5 0.048 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81497.1 - 0.085 11.8 0.1 0.088 11.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81498.1 - 0.29 11.1 9.4 0.46 10.5 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX81498.1 - 2.7 5.5 13.0 3.4 5.2 13.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX81498.1 - 8.4 6.8 7.3 12 6.3 7.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR PF12789.7 EAX81500.1 - 1.9e-15 56.6 6.8 1.9e-15 56.6 6.8 4.7 3 1 1 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX81500.1 - 0.12 12.1 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DDR PF08841.10 EAX81503.1 - 0.1 11.5 0.1 0.098 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81504.1 - 0.05 13.6 4.2 0.058 13.4 4.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 EAX81507.1 - 6.2e-280 928.3 50.7 2.5e-151 504.6 16.7 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX81507.1 - 0.0019 18.4 0.2 0.064 13.6 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated Phage_fiber_2 PF03406.13 EAX81507.1 - 1.1 8.9 5.5 1.6 8.3 2.4 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat PG_binding_2 PF08823.11 EAX81508.1 - 0.014 15.7 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF3835 PF12927.7 EAX81508.1 - 1.5 9.7 6.0 8.1 7.4 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) T5orf172 PF10544.9 EAX81509.1 - 2.9e-06 27.8 0.2 7.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81509.1 - 0.011 15.6 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX81509.1 - 0.012 15.2 0.9 0.13 11.7 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81510.1 - 2.8e-117 390.4 11.8 3.6e-117 390.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX81510.1 - 0.04 14.2 0.1 0.1 12.8 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX81510.1 - 0.19 11.6 1.4 0.51 10.2 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81510.1 - 0.2 12.1 3.2 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX81511.1 - 1.9e-06 28.4 0.1 4.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81511.1 - 0.0044 16.8 0.1 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain Ank_2 PF12796.7 EAX81512.1 - 4.1e-13 49.7 0.2 3.4e-06 27.5 0.0 3.6 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX81512.1 - 1.1e-11 43.8 0.2 0.0085 16.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX81512.1 - 1.1e-08 35.4 0.0 0.00033 21.2 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX81512.1 - 2.9e-07 30.6 0.0 0.11 12.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX81512.1 - 8.5e-06 26.0 0.0 2 8.8 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) B5 PF03484.15 EAX81512.1 - 0.11 12.9 0.1 0.38 11.1 0.1 2.0 2 1 0 2 2 2 0 tRNA synthetase B5 domain Trm5_N PF18093.1 EAX81512.1 - 1.5 8.8 5.2 11 6.0 0.1 3.8 5 0 0 5 5 5 0 tRNA methyltransferase 5 N-terminal domain FlxA PF14282.6 EAX81513.1 - 0.042 13.8 4.9 0.051 13.6 4.9 1.0 1 0 0 1 1 1 0 FlxA-like protein Acetyltransf_11 PF13720.6 EAX81513.1 - 0.093 13.2 0.4 0.1 13.1 0.4 1.0 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CorA PF01544.18 EAX81513.1 - 0.44 9.8 3.8 0.46 9.8 3.8 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Shisa PF13908.6 EAX81514.1 - 1.3e-06 28.8 5.9 2.4e-06 27.9 5.9 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EAX81514.1 - 0.00057 20.7 0.3 0.0013 19.6 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 EAX81514.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TMEM154 PF15102.6 EAX81514.1 - 0.017 15.1 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Comm PF15957.5 EAX81514.1 - 0.033 14.5 2.9 0.061 13.7 1.9 1.9 2 0 0 2 2 2 0 Commissureless Cadherin_C_2 PF16492.5 EAX81514.1 - 0.1 13.3 1.7 0.32 11.8 1.7 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MLANA PF14991.6 EAX81514.1 - 0.12 12.7 0.4 0.27 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein melan-A EVC2_like PF12297.8 EAX81514.1 - 0.36 9.5 0.8 0.55 8.9 0.8 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Mucin PF01456.17 EAX81514.1 - 0.53 10.3 6.3 1.1 9.3 6.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3839 PF12943.7 EAX81515.1 - 1.1e-156 519.5 12.2 1.3e-156 519.2 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81515.1 - 0.15 12.6 6.1 2.3 8.8 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81515.1 - 2.1 8.9 5.1 2.3 8.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX81516.1 - 3.6e-08 33.2 1.2 4.1e-08 33.0 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81516.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81516.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81516.1 - 0.088 12.8 0.3 0.7 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF1493 PF07377.12 EAX81517.1 - 0.015 15.8 0.7 0.028 14.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX81518.1 - 2e-30 104.6 13.8 2e-30 104.6 13.8 4.7 4 1 1 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX81518.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Trypan_PARP PF05887.11 EAX81519.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX81522.1 - 1.4e-100 335.8 9.0 1.6e-100 335.6 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1493 PF07377.12 EAX81523.1 - 0.028 14.9 1.9 0.029 14.8 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) CENP-B_dimeris PF09026.10 EAX81524.1 - 9.7 6.7 14.1 22 5.5 0.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PTR PF12789.7 EAX81525.1 - 1.7e-17 63.2 34.2 1.9e-08 34.2 5.2 6.8 6 1 1 7 7 7 6 Phage tail repeat like LIFR_D2 PF17971.1 EAX81525.1 - 0.0016 18.6 0.4 0.48 10.6 0.0 2.5 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain OKR_DC_1_C PF03711.15 EAX81525.1 - 0.16 12.2 0.5 10 6.4 0.0 2.7 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain EpuA PF11772.8 EAX81525.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PatG_C PF18065.1 EAX81525.1 - 0.42 10.6 2.4 4.6 7.2 0.0 2.8 3 0 0 3 3 3 0 PatG C-terminal DUF1471 PF07338.13 EAX81525.1 - 0.49 10.4 5.5 35 4.5 0.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1471) EMP24_GP25L PF01105.24 EAX81525.1 - 5.5 6.9 8.9 5.1 7.0 2.0 3.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD T5orf172 PF10544.9 EAX81526.1 - 7.1e-07 29.7 0.2 1.8e-06 28.4 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81526.1 - 0.013 15.3 1.2 0.047 13.5 0.3 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX81526.1 - 0.016 14.7 1.0 0.16 11.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81527.1 - 2.1e-99 331.9 13.5 2.7e-99 331.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX81527.1 - 0.031 14.5 0.1 0.067 13.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX81527.1 - 0.14 12.0 1.4 0.4 10.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX81528.1 - 9.8e-156 516.3 14.4 1.4e-155 515.8 14.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81528.1 - 0.065 13.7 3.4 0.72 10.4 0.1 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81528.1 - 0.17 12.2 4.3 14 6.1 0.0 3.9 4 1 0 4 4 4 0 Tup N-terminal THOC7 PF05615.13 EAX81528.1 - 0.32 11.3 3.3 0.21 11.8 0.4 2.2 2 2 0 2 2 2 0 Tho complex subunit 7 DUF3839 PF12943.7 EAX81529.1 - 3.8e-80 268.8 9.5 5.1e-80 268.4 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81529.1 - 0.018 15.5 0.4 0.022 15.2 0.4 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX81529.1 - 0.063 13.8 0.5 0.11 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) BRE1 PF08647.11 EAX81529.1 - 0.26 11.4 3.0 4.8 7.3 0.6 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Pox_A32 PF04665.12 EAX81530.1 - 2e-06 27.5 3.0 4.2e-06 26.4 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81530.1 - 0.0038 16.9 0.2 0.0054 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX81530.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX81530.1 - 0.042 13.4 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81530.1 - 0.046 13.4 0.2 0.18 11.5 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81530.1 - 0.2 11.6 2.8 1.1 9.3 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX81530.1 - 0.32 11.2 8.3 4.5 7.5 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3781 PF12636.7 EAX81531.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Trigger_C PF05698.14 EAX81532.1 - 7.7e-07 29.3 0.0 0.00032 20.8 0.0 2.9 1 1 2 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus DUF3644 PF12358.8 EAX81532.1 - 2.6e-05 24.6 1.5 1.5 9.4 0.0 4.7 2 2 3 5 5 5 2 Protein of unknown function (DUF3644) SNAD3 PF18749.1 EAX81532.1 - 3.8e-05 23.0 0.1 0.11 11.6 0.0 2.9 1 1 2 3 3 3 2 Secreted Novel AID/APOBEC-like Deaminase 3 DUF1103 PF06513.11 EAX81532.1 - 0.0073 15.9 0.1 0.015 14.9 0.1 1.6 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) Speriolin_N PF15058.6 EAX81532.1 - 0.0079 16.3 1.3 2.9 7.9 0.1 2.2 1 1 1 2 2 2 2 Speriolin N terminus AdoMet_Synthase PF01941.19 EAX81532.1 - 0.025 13.4 0.4 0.83 8.4 0.0 2.7 1 1 2 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) MetOD1 PF18546.1 EAX81532.1 - 0.044 13.8 1.5 0.7 9.9 0.4 2.7 1 1 1 2 2 2 0 Metanogen output domain 1 CCDC117 PF15810.5 EAX81532.1 - 0.2 12.0 3.6 2.3 8.5 0.2 3.0 1 1 3 4 4 4 0 Coiled-coil domain-containing protein 117 Hexapep_loop PF18776.1 EAX81532.1 - 0.27 10.9 2.5 1.1e+02 2.6 0.0 3.8 4 0 0 4 4 4 0 Hexapeptide repeat including loop DUF1340 PF07067.11 EAX81532.1 - 2.8 7.3 9.9 1.8 7.9 1.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1340) Ery_res_leader2 PF08057.11 EAX81532.1 - 3.8 8.3 4.6 96 4.1 0.1 3.6 3 0 0 3 3 2 0 Erythromycin resistance leader peptide DDE_Tnp_ISL3 PF01610.17 EAX81533.1 - 2.2e-05 24.3 0.2 2.7e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Transposase DUF4107 PF13389.6 EAX81534.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX81534.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Trypan_PARP PF05887.11 EAX81535.1 - 0.097 12.6 10.3 0.15 12.0 10.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX81536.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81536.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX81537.1 - 4.1e-156 517.6 12.9 5e-156 517.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81537.1 - 0.32 11.5 6.2 2.1 8.8 0.6 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX81537.1 - 0.78 10.1 3.8 2.3 8.5 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX81537.1 - 2.4 8.7 5.3 1.1 9.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX81538.1 - 7.7e-42 141.7 0.0 1.2e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain PTR PF12789.7 EAX81540.1 - 1e-21 76.8 8.9 3.1e-16 59.2 2.5 4.6 6 0 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX81540.1 - 0.037 13.8 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX81540.1 - 0.058 13.3 2.4 2.4 8.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) YmaF PF12788.7 EAX81540.1 - 3.9 8.1 18.4 1.8 9.2 3.0 4.2 2 2 0 2 2 2 0 YmaF family Trypan_PARP PF05887.11 EAX81541.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX81542.1 - 6.2e-155 513.7 12.5 7.8e-155 513.4 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81542.1 - 0.042 14.3 1.8 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX81542.1 - 0.25 11.2 1.8 0.52 10.1 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81542.1 - 0.34 11.4 3.1 10 6.6 0.2 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81542.1 - 1.6 9.1 5.6 12 6.3 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal Lectin_legB PF00139.19 EAX81543.1 - 0.0016 18.0 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX81543.1 - 0.002 18.6 0.1 0.0047 17.5 0.0 1.7 2 0 0 2 2 2 1 T5orf172 domain DUF3148 PF11347.8 EAX81543.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Podoplanin PF05808.11 EAX81544.1 - 0.00043 20.4 0.8 0.00072 19.7 0.0 1.6 1 1 1 2 2 2 1 Podoplanin Mid2 PF04478.12 EAX81544.1 - 0.002 18.0 2.4 0.0023 17.8 1.2 1.8 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor TMEM65 PF10507.9 EAX81544.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 65 Rax2 PF12768.7 EAX81544.1 - 0.023 14.1 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Amnionless PF14828.6 EAX81544.1 - 0.05 12.4 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 EAX81544.1 - 0.05 13.4 4.2 0.09 12.5 4.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECF_trnsprt PF12822.7 EAX81544.1 - 0.053 13.6 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component AI-2E_transport PF01594.16 EAX81544.1 - 0.077 12.1 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 AI-2E family transporter Syndecan PF01034.20 EAX81544.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Nramp PF01566.18 EAX81544.1 - 0.16 10.9 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein KilA-N PF04383.13 EAX81545.1 - 1.3e-41 140.9 1.1 2.8e-41 139.9 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81545.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX81545.1 - 0.025 13.8 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX81545.1 - 0.16 10.5 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) LOH1CR12 PF10158.9 EAX81545.1 - 1.3 9.1 4.7 3.5 7.6 0.3 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX81546.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81546.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81546.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81546.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX81547.1 - 1.1e-34 118.6 0.6 2.2e-34 117.7 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81547.1 - 0.026 15.1 0.0 0.078 13.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX81548.1 - 1.4e-06 28.8 0.2 2.7e-06 27.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX81548.1 - 0.17 12.6 0.4 0.46 11.2 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4107 PF13389.6 EAX81549.1 - 5.2e-72 241.3 4.1 7.9e-72 240.7 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81549.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4108 PF13390.6 EAX81550.1 - 5.5e-53 178.7 4.0 6.4e-53 178.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX81550.1 - 0.1 12.9 0.1 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide NMT PF01233.19 EAX81551.1 - 0.55 10.1 3.0 0.21 11.4 0.3 1.8 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF3464 PF11947.8 EAX81551.1 - 0.65 9.7 2.1 1.1 9.0 2.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX81551.1 - 3.1 7.7 4.9 6.2 6.8 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX81552.1 - 6.5e-07 29.1 2.7 6.5e-07 29.1 2.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81552.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81552.1 - 5.7e-05 22.9 0.3 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81552.1 - 0.00016 21.8 3.5 0.00032 20.7 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81552.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81552.1 - 0.0013 18.6 0.9 0.0036 17.1 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81552.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81552.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81552.1 - 0.066 12.8 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81552.1 - 0.086 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81552.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81552.1 - 0.31 11.3 4.7 4.7 7.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX81553.1 - 1.2e-16 60.9 3.4 2e-16 60.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX81553.1 - 0.12 12.8 1.0 0.55 10.7 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX81554.1 - 1.8e-32 111.5 0.4 4.2e-32 110.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81555.1 - 1.3e-06 28.9 0.3 2.7e-06 27.9 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain ArsC PF03960.15 EAX81556.1 - 0.16 12.0 1.6 0.29 11.2 1.6 1.5 1 1 0 1 1 1 0 ArsC family Myb_DNA-binding PF00249.31 EAX81557.1 - 2.7e-12 46.7 0.1 3.3e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX81557.1 - 2.9e-11 43.4 1.8 1.7e-10 41.0 1.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PAS_10 PF13596.6 EAX81557.1 - 0.038 14.6 1.1 4 8.1 0.2 2.3 2 0 0 2 2 2 0 PAS domain Binary_toxB_3 PF17476.2 EAX81557.1 - 0.081 13.1 1.9 0.094 12.9 0.8 1.7 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 Gly-zipper_Omp PF13488.6 EAX81558.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX81558.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TMP PF05017.14 EAX81561.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX81562.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX81564.1 - 2.6e-46 157.1 3.4 3e-46 156.9 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX81564.1 - 0.14 11.2 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Ank_2 PF12796.7 EAX81565.1 - 1.9e-05 25.2 0.1 0.13 12.9 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX81565.1 - 0.002 18.1 2.6 0.002 18.1 2.6 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX81565.1 - 0.0036 17.7 0.0 33 5.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX81565.1 - 0.084 13.5 0.0 43 4.8 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) KilA-N PF04383.13 EAX81566.1 - 7.2e-11 41.9 0.2 1.4e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX81566.1 - 0.22 10.9 0.2 0.53 9.7 0.2 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX81567.1 - 7.1e-155 513.5 11.8 9e-155 513.2 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81567.1 - 0.44 10.9 4.6 1.6 9.0 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX81567.1 - 0.89 10.0 5.6 3.8 8.0 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2897 PF11446.8 EAX81568.1 - 0.99 9.3 3.0 1.6 8.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4107 PF13389.6 EAX81570.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81571.1 - 8.6e-157 519.8 12.7 1e-156 519.5 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81571.1 - 0.082 13.2 1.2 2.7 8.3 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX81571.1 - 0.11 12.9 0.3 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81571.1 - 0.35 11.4 6.9 2.2 8.8 0.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3447 PF11929.8 EAX81572.1 - 3.8e-37 126.1 4.9 3.8e-37 126.1 4.9 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX81572.1 - 0.00015 22.3 0.1 0.0058 17.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX81572.1 - 0.017 15.7 0.2 31 5.3 0.0 4.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF3839 PF12943.7 EAX81573.1 - 3.2e-153 508.1 12.7 4.1e-153 507.7 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81573.1 - 2.6 8.5 7.0 1.9 9.0 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX81574.1 - 3.8e-06 26.5 0.6 4.5e-06 26.3 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3783 PF12646.7 EAX81574.1 - 0.069 13.1 0.3 0.53 10.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Zot PF05707.12 EAX81574.1 - 0.085 12.5 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) KilA-N PF04383.13 EAX81575.1 - 2e-32 111.4 0.6 4.2e-32 110.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain RRM_1 PF00076.22 EAX81576.1 - 3e-31 107.1 0.0 4e-12 45.8 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX81576.1 - 4.3e-07 29.6 0.0 9.6e-06 25.2 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX81576.1 - 0.011 15.8 0.1 1.9 8.7 0.0 3.1 2 1 1 3 3 3 0 RNA recognition motif BRAP2 PF07576.12 EAX81576.1 - 0.046 13.9 0.0 3.7 7.8 0.0 3.0 3 0 0 3 3 3 0 BRCA1-associated protein 2 PHM7_cyt PF14703.6 EAX81576.1 - 0.05 13.8 0.0 10 6.3 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Mlf1IP PF10248.9 EAX81577.1 - 2.2e-12 47.3 8.3 4e-12 46.4 2.6 2.2 1 1 1 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein ORC_WH_C PF18137.1 EAX81577.1 - 1.4 8.9 8.7 0.18 11.8 4.4 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal HNH_3 PF13392.6 EAX81578.1 - 8.7e-08 31.8 0.3 1.7e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease PSP PF04046.16 EAX81579.1 - 0.12 12.3 1.6 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX81581.1 - 1.3e-62 210.0 5.9 1.4e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX81582.1 - 1.1 9.2 4.2 2.2 8.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX81584.1 - 1.7e-154 512.3 11.6 2.1e-154 512.0 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81584.1 - 0.039 14.4 0.7 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81584.1 - 0.11 12.9 3.5 3.1 8.3 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX81584.1 - 0.14 12.5 1.1 0.78 10.1 0.2 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF4168 PF13767.6 EAX81584.1 - 0.48 11.6 2.8 24 6.2 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF2408 PF10303.9 EAX81584.1 - 0.71 10.4 5.0 0.36 11.4 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX81585.1 - 2.2e-19 69.3 20.1 1.4e-08 34.6 4.3 4.6 4 0 0 4 4 4 4 Phage tail repeat like PatG_C PF18065.1 EAX81585.1 - 0.068 13.1 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 PatG C-terminal malic PF00390.19 EAX81587.1 - 1.1e-69 233.9 0.0 1.7e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EAX81587.1 - 2.6e-26 92.5 0.5 3.5e-26 92.0 0.5 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 EAX81587.1 - 0.11 11.7 1.3 1 8.6 0.1 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Arb2 PF09757.9 EAX81587.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain Chal_sti_synt_N PF00195.19 EAX81588.1 - 0.14 11.5 0.7 0.27 10.6 0.7 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF4107 PF13389.6 EAX81589.1 - 1.1e-33 116.7 3.4 1.3e-33 116.4 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX81589.1 - 0.042 12.3 0.8 0.04 12.3 0.8 1.0 1 0 0 1 1 1 0 Lipoxygenase FliJ PF02050.16 EAX81590.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein CRM1_repeat_3 PF18787.1 EAX81592.1 - 2.9e-07 30.5 13.0 9.3 6.5 0.1 6.0 6 0 0 6 6 6 6 CRM1 / Exportin repeat 3 DUF5106 PF17127.4 EAX81592.1 - 4e-06 27.2 0.1 2.4 8.4 0.0 3.6 1 1 4 5 5 5 5 Domain of unknown function (DUF5106) A2L_zn_ribbon PF08792.10 EAX81592.1 - 0.00057 19.5 18.1 6.2 6.7 0.4 5.5 5 0 0 5 5 5 5 A2L zinc ribbon domain Wyosine_form PF08608.12 EAX81592.1 - 0.0019 18.5 9.1 24 5.4 0.1 5.2 5 0 0 5 5 5 2 Wyosine base formation DUF1186 PF06685.11 EAX81592.1 - 0.0031 16.9 1.0 1.6 8.0 0.1 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1186) NOD PF06816.13 EAX81592.1 - 7.6 6.2 12.0 82 2.9 0.1 4.8 2 1 4 6 6 6 0 NOTCH protein Polyoma_agno PF01736.16 EAX81592.1 - 8.6 6.2 25.7 20 5.0 1.2 5.5 1 1 5 6 6 6 0 Polyomavirus agnoprotein PTR PF12789.7 EAX81594.1 - 1.3e-08 34.7 4.8 1.3e-08 34.7 4.8 5.8 6 1 1 7 7 7 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX81594.1 - 0.0032 17.7 0.0 21 5.3 0.0 3.3 1 1 1 3 3 3 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX81594.1 - 0.0096 15.9 2.3 22 5.0 0.1 3.3 3 0 0 3 3 3 0 Interleukin 2 Toprim PF01751.22 EAX81594.1 - 0.019 15.2 0.2 19 5.6 0.0 3.1 3 0 0 3 3 3 0 Toprim domain Ribosomal_S4e PF00900.20 EAX81594.1 - 0.019 14.9 0.5 60 3.6 0.0 3.4 3 0 0 3 3 3 0 Ribosomal family S4e DUF4805 PF16063.5 EAX81594.1 - 0.027 13.8 3.2 22 4.3 0.0 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4805) HCNGP PF07818.13 EAX81594.1 - 0.033 14.8 0.1 1.1e+02 3.6 0.0 3.5 3 0 0 3 3 3 0 HCNGP-like protein TT_ORF2a PF08197.11 EAX81594.1 - 0.033 14.2 0.0 48 4.1 0.0 3.3 3 0 0 3 3 3 0 pORF2a truncated protein ATG7_N PF16420.5 EAX81594.1 - 0.055 13.1 1.9 8 6.0 0.1 2.8 1 1 1 2 2 2 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF3781 PF12636.7 EAX81595.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX81596.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81596.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81597.1 - 0.073 13.0 10.9 0.098 12.6 10.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MULE PF10551.9 EAX81598.1 - 3.2e-09 37.1 0.5 9.2e-09 35.6 0.5 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF3781 PF12636.7 EAX81599.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX81600.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX81601.1 - 0.12 12.3 12.0 0.13 12.2 12.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81601.1 - 0.83 10.1 5.7 0.95 9.9 5.7 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX81602.1 - 1.4e-34 118.3 0.2 1.4e-34 118.3 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81602.1 - 0.0054 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX81603.1 - 7.1e-07 29.7 0.1 1.7e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81603.1 - 0.044 13.3 0.3 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain GPS2_interact PF15784.5 EAX81605.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81605.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX81606.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX81607.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX81607.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF842 PF05811.13 EAX81608.1 - 0.0081 15.9 0.5 0.0088 15.7 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Styelin PF17562.2 EAX81608.1 - 0.028 14.8 0.2 0.036 14.4 0.2 1.2 1 0 0 1 1 1 0 Styelin DUF1729 PF08354.10 EAX81608.1 - 0.067 12.1 0.0 0.069 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) CUE PF02845.16 EAX81609.1 - 0.0069 16.1 0.0 4.1 7.2 0.0 3.6 1 1 3 4 4 4 1 CUE domain HCBP_related PF06594.11 EAX81609.1 - 0.16 12.0 0.0 2.1e+02 1.9 0.0 3.7 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain Qua1 PF16274.5 EAX81609.1 - 0.3 10.9 5.5 14 5.7 0.1 3.7 1 1 3 4 4 4 0 Qua1 domain Chordopox_A30L PF06015.12 EAX81609.1 - 0.78 9.6 5.9 10 6.0 0.4 2.4 1 1 2 3 3 3 0 Chordopoxvirus A30L protein KilA-N PF04383.13 EAX81610.1 - 2.6e-34 117.4 0.2 6.4e-34 116.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX81611.1 - 1.5e-07 31.1 2.5 2.3e-07 30.6 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81611.1 - 0.0094 15.6 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81611.1 - 0.057 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81611.1 - 0.062 13.0 0.2 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81611.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) T5orf172 PF10544.9 EAX81612.1 - 3.9e-07 30.5 0.7 4.9e-06 27.0 0.4 2.5 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX81612.1 - 0.03 14.2 0.1 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX81612.1 - 0.063 12.8 0.2 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain DNA_pol_B_2 PF03175.13 EAX81613.1 - 6.3e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX81613.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX81613.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX81614.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX81614.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MULE PF10551.9 EAX81616.1 - 1e-06 29.1 0.0 2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DNA_pol_B_2 PF03175.13 EAX81617.1 - 1.3e-08 34.1 2.0 1.5e-08 34.0 1.0 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX81617.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX81617.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX81618.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX81618.1 - 0.062 13.3 0.6 0.088 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX81619.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX81619.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Trypan_PARP PF05887.11 EAX81620.1 - 0.012 15.6 10.2 0.013 15.4 10.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-binding PF00249.31 EAX81621.1 - 2.6e-32 110.7 5.2 2.4e-16 59.6 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX81621.1 - 7.8e-26 90.1 5.7 4.8e-15 55.6 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX81621.1 - 5.3e-06 26.2 0.8 0.00025 20.9 0.2 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EAX81621.1 - 2.3e-05 24.4 0.1 0.004 17.2 0.2 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EAX81621.1 - 2.3e-05 24.4 0.1 0.29 11.2 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX81621.1 - 0.0013 18.9 0.4 0.23 11.7 0.2 2.7 1 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Ank_2 PF12796.7 EAX81622.1 - 2.3e-43 146.7 13.1 1.5e-12 47.9 0.8 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX81622.1 - 2.1e-40 136.6 7.9 4.5e-12 46.3 0.0 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX81622.1 - 3.8e-38 125.1 9.2 5.6e-06 26.3 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EAX81622.1 - 5.6e-32 108.8 8.5 1.2e-05 25.5 0.0 7.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX81622.1 - 1.2e-29 102.0 6.5 3.9e-07 30.2 0.0 6.3 2 2 6 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX81622.1 - 3.6e-19 68.5 27.0 6.3e-18 64.5 6.6 5.1 2 1 4 6 6 6 3 Domain of unknown function (DUF3447) Shigella_OspC PF06128.11 EAX81622.1 - 4.2e-06 26.7 9.8 0.22 11.2 0.0 4.3 3 2 1 4 4 4 3 Shigella flexneri OspC protein Mic1 PF07035.12 EAX81622.1 - 0.0046 16.7 0.3 0.31 10.7 0.1 3.1 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like CppA_N PF14506.6 EAX81622.1 - 0.015 15.3 0.8 4.1 7.5 0.1 2.6 1 1 1 2 2 2 0 CppA N-terminal LRR_5 PF13306.6 EAX81623.1 - 7e-96 317.0 15.1 8.2e-35 119.6 0.5 4.3 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX81623.1 - 1.9e-07 30.7 0.0 2.6 7.9 0.0 7.2 7 2 2 9 9 9 1 Leucine rich repeat VSP PF03302.13 EAX81623.1 - 0.00085 18.3 0.7 0.0014 17.5 0.7 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EAX81623.1 - 0.00095 19.3 0.9 0.0034 17.5 0.9 1.9 1 0 0 1 1 1 1 Podoplanin Borrelia_P13 PF05628.12 EAX81623.1 - 0.0025 17.8 22.9 1.4 8.9 0.1 6.2 4 1 3 8 8 6 3 Borrelia membrane protein P13 ECSCR PF15820.5 EAX81623.1 - 0.01 15.7 0.5 0.04 13.7 0.5 2.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CYYR1 PF10873.8 EAX81623.1 - 0.013 15.9 1.4 0.024 15.1 1.4 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Extensin-like_C PF06904.12 EAX81623.1 - 0.014 15.5 0.0 34 4.4 0.0 3.5 2 1 1 3 3 3 0 Extensin-like protein C-terminus YajC PF02699.15 EAX81623.1 - 0.017 15.0 2.8 0.2 11.5 0.1 3.6 4 0 0 4 4 4 0 Preprotein translocase subunit SKG6 PF08693.10 EAX81623.1 - 0.038 13.4 7.2 0.072 12.5 7.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EAX81623.1 - 0.041 13.8 1.0 0.088 12.7 1.0 1.6 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 EAX81623.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 EAX81623.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 EAX81623.1 - 0.087 12.4 0.8 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 EAX81623.1 - 0.12 13.3 1.1 0.25 12.3 1.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAX81623.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless FeoB_associated PF12669.7 EAX81623.1 - 0.22 11.9 3.6 0.46 10.9 3.6 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein FNIP PF05725.12 EAX81623.1 - 0.24 11.6 10.1 8.5 6.6 0.0 6.6 10 0 0 10 10 9 0 FNIP Repeat YflT PF11181.8 EAX81625.1 - 9e-05 22.9 9.4 2.6 8.6 0.3 4.3 1 1 4 5 5 5 5 Heat induced stress protein YflT HSA PF07529.13 EAX81625.1 - 0.00046 20.5 5.3 21 5.5 0.1 4.9 1 1 5 6 6 6 0 HSA Calpain_u2 PF16648.5 EAX81625.1 - 0.001 19.5 21.7 3.5 8.2 0.7 5.6 1 1 5 6 6 6 5 Unstructured region on Calpain-3 ErmC PF06308.11 EAX81625.1 - 0.0017 18.7 5.1 2.1e+02 2.3 0.0 5.9 6 0 0 6 6 6 0 23S rRNA methylastransferase leader peptide (ErmCL) Cauli_AT PF03233.13 EAX81625.1 - 0.0024 17.8 16.0 0.25 11.3 3.6 2.9 1 1 2 3 3 3 3 Aphid transmission protein MscS_porin PF12795.7 EAX81625.1 - 0.01 15.4 0.7 16 4.9 0.1 3.0 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain DKNYY PF13644.6 EAX81625.1 - 0.02 15.7 3.9 0.36 11.6 3.9 2.3 1 1 0 1 1 1 0 DKNYY family Connexin50 PF03509.14 EAX81625.1 - 0.058 14.2 11.6 91 4.0 0.5 5.7 1 1 4 5 5 5 0 Gap junction alpha-8 protein (Cx50) DUF4612 PF15389.6 EAX81625.1 - 0.14 13.2 17.5 12 7.0 1.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4612) DUF5344 PF17279.2 EAX81625.1 - 0.23 12.1 10.8 20 5.8 0.3 3.7 1 1 4 5 5 5 0 Family of unknown function (DUF5344) APC_u5 PF16630.5 EAX81625.1 - 1 10.4 5.1 35 5.5 0.3 2.7 1 1 4 5 5 5 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs SRR PF07709.11 EAX81625.1 - 1.3 9.7 13.3 3.7e+02 2.3 0.1 6.1 6 0 0 6 6 6 0 Seven Residue Repeat PASTA PF03793.19 EAX81625.1 - 1.6 8.6 7.6 3.6e+02 1.1 0.0 5.2 6 0 0 6 6 6 0 PASTA domain DUF3781 PF12636.7 EAX81626.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX81627.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81627.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81628.1 - 0.14 12.1 12.5 0.16 12.0 12.5 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81628.1 - 4.1 7.9 7.1 4.7 7.7 7.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX81629.1 - 5.7e-07 29.2 2.6 5.7e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81629.1 - 3.1e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81629.1 - 0.00012 21.8 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81629.1 - 0.00019 21.5 3.9 0.00044 20.3 3.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81629.1 - 0.00062 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81629.1 - 0.0013 18.6 0.7 0.0022 17.8 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81629.1 - 0.0019 17.9 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81629.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81629.1 - 0.072 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81629.1 - 0.084 13.3 0.1 0.69 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81629.1 - 0.091 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein KilA-N PF04383.13 EAX81630.1 - 1.7e-41 140.5 0.3 4e-41 139.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81630.1 - 0.015 15.9 0.1 0.039 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX81632.1 - 4.6e-120 399.5 10.7 5.7e-120 399.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81632.1 - 0.068 13.6 1.4 11 6.6 0.0 2.9 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX81632.1 - 0.12 12.2 1.5 0.42 10.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX81633.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81633.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81633.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81633.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81633.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81633.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81633.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81633.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81633.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81633.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81633.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81633.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Phage_fiber PF03335.13 EAX81635.1 - 8.1 6.9 21.4 1.5 9.1 2.6 3.5 3 0 0 3 3 3 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX81636.1 - 5.1e-159 527.1 12.5 6.3e-159 526.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81636.1 - 0.34 11.4 6.2 2.6 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81636.1 - 1 9.7 5.7 14 6.0 0.1 4.1 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX81636.1 - 3.4 8.2 7.1 0.39 11.3 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX81637.1 - 9.9e-07 28.6 1.0 1.3e-06 28.2 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF1947 PF09183.10 EAX81638.1 - 0.013 15.7 0.7 0.12 12.7 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) EpuA PF11772.8 EAX81638.1 - 0.029 14.1 0.0 0.099 12.3 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF3839 PF12943.7 EAX81639.1 - 3.2e-153 508.1 13.3 4e-153 507.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX81639.1 - 0.22 11.9 1.7 0.93 9.8 0.5 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit APC_u14 PF16635.5 EAX81639.1 - 0.41 11.2 3.0 0.82 10.2 1.6 2.1 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX81639.1 - 4.5 7.8 8.9 2.7 8.5 1.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LSM PF01423.22 EAX81640.1 - 2.4e-13 49.5 0.0 2.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Fringe PF02434.16 EAX81641.1 - 3.2e-10 39.9 0.1 4.5e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EAX81641.1 - 0.0018 17.7 0.6 0.0033 16.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Stealth_CR2 PF11380.8 EAX81641.1 - 0.0024 18.0 1.5 0.21 11.8 0.1 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 IstB_IS21 PF01695.17 EAX81643.1 - 1.6e-05 24.7 0.4 0.14 11.9 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX81643.1 - 2.4e-05 24.6 0.1 0.00018 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81643.1 - 0.00011 22.2 3.2 0.00024 21.2 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81643.1 - 0.00046 20.0 0.1 0.00085 19.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX81643.1 - 0.00057 19.4 3.0 0.00057 19.4 3.0 2.0 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX81643.1 - 0.001 18.9 0.5 0.0027 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81643.1 - 0.0011 18.7 0.6 0.0067 16.1 0.6 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81643.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX81643.1 - 0.05 13.2 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81643.1 - 0.056 13.9 0.1 0.52 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX81643.1 - 0.063 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX81643.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81643.1 - 0.33 11.2 4.3 8.5 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX81644.1 - 3.7e-57 192.3 3.2 4.1e-57 192.1 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX81644.1 - 0.11 11.5 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PSP PF04046.16 EAX81645.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX81646.1 - 1e-33 115.5 0.8 1.9e-33 114.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81646.1 - 0.056 14.1 0.0 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX81646.1 - 0.26 12.0 1.3 10 6.9 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX81648.1 - 3.8e-07 29.8 2.0 3.8e-07 29.8 2.0 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81648.1 - 2.9e-05 24.3 0.2 0.00021 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81648.1 - 0.00013 22.1 2.7 0.00029 20.9 2.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX81648.1 - 0.00043 20.1 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX81648.1 - 0.00056 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81648.1 - 0.0013 18.6 0.6 0.0025 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81648.1 - 0.0017 18.0 0.4 0.012 15.3 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81648.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81648.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81648.1 - 0.082 13.3 0.1 0.66 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81648.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2666 PF10869.8 EAX81648.1 - 0.99 9.6 8.4 7.4 6.8 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PALP PF00291.25 EAX81652.1 - 2.6e-65 220.7 0.4 3.8e-65 220.2 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_S6e PF01092.19 EAX81653.1 - 0.034 14.1 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S6e PapD_N PF00345.20 EAX81655.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX81655.1 - 0.14 12.1 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX81656.1 - 0.02 15.3 0.7 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX81656.1 - 1.6 7.7 4.0 1.7 7.6 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX81656.1 - 3.8 8.2 6.6 8.4 7.1 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX81656.1 - 4.1 7.4 7.6 4.4 7.3 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX81657.1 - 1.1e-71 240.2 3.4 1.5e-71 239.8 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81657.1 - 0.089 13.2 0.5 0.28 11.6 0.1 1.9 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF4107 PF13389.6 EAX81659.1 - 2.5e-30 105.8 2.4 2.7e-30 105.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX81660.1 - 4e-32 111.6 2.8 7.4e-32 110.8 2.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81662.1 - 7.3e-117 389.1 10.5 9.2e-117 388.7 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Treslin_N PF15292.6 EAX81662.1 - 0.037 12.4 1.0 0.045 12.1 1.0 1.1 1 0 0 1 1 1 0 Treslin N-terminus KELK PF15796.5 EAX81662.1 - 0.059 13.8 0.8 1.8 9.1 0.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX81662.1 - 0.11 12.3 0.9 0.41 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase YmgB PF10798.8 EAX81663.1 - 0.0091 15.8 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR DUF3839 PF12943.7 EAX81665.1 - 1.5e-156 519.0 14.3 1.9e-156 518.7 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81665.1 - 0.099 12.5 1.1 0.36 10.7 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81665.1 - 0.47 10.9 6.1 2 8.9 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDR PF08841.10 EAX81666.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX81666.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1910 PF08928.10 EAX81668.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) DUF4108 PF13390.6 EAX81669.1 - 3e-76 254.2 11.4 3.4e-76 254.0 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAX81669.1 - 0.42 11.6 3.1 1 10.4 3.1 1.6 1 0 0 1 1 1 0 Deacetylase PdaC DUF2207 PF09972.9 EAX81670.1 - 0.0046 15.8 6.0 0.0056 15.5 6.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4625 PF15418.6 EAX81670.1 - 0.013 15.8 1.2 3.7 7.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4625) RIFIN PF02009.16 EAX81670.1 - 0.014 15.3 5.8 0.018 14.9 5.8 1.1 1 0 0 1 1 1 0 Rifin MG2 PF01835.19 EAX81670.1 - 0.05 14.1 0.2 15 6.1 0.0 2.5 2 1 0 2 2 2 0 MG2 domain Amnionless PF14828.6 EAX81670.1 - 0.067 12.0 0.2 0.09 11.6 0.2 1.2 1 0 0 1 1 1 0 Amnionless PKD PF00801.20 EAX81670.1 - 0.09 12.6 0.1 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 PKD domain DUF5305 PF17231.2 EAX81670.1 - 0.1 12.0 10.7 0.036 13.5 8.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF2914 PF11141.8 EAX81670.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) He_PIG PF05345.12 EAX81670.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.9 3 0 0 3 3 3 0 Putative Ig domain Ald_Xan_dh_C PF01315.22 EAX81670.1 - 0.37 11.2 3.9 0.81 10.1 3.9 1.5 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DUF3839 PF12943.7 EAX81672.1 - 1.3e-24 87.0 4.1 2e-24 86.4 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX81672.1 - 0.05 13.9 0.9 0.17 12.2 0.1 2.0 1 1 1 2 2 2 0 PRD domain DUF3839 PF12943.7 EAX81673.1 - 7.4e-97 323.6 5.3 8.4e-97 323.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81673.1 - 0.0063 16.0 0.2 0.0078 15.7 0.2 1.3 1 1 0 1 1 1 1 Z1 domain DUF3839 PF12943.7 EAX81674.1 - 9.2e-156 516.4 13.7 1.2e-155 516.0 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81674.1 - 0.018 15.5 1.4 0.16 12.4 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81674.1 - 0.33 11.4 6.6 1.8 9.1 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81674.1 - 0.81 10.3 7.1 0.31 11.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX81675.1 - 1e-06 29.2 0.2 3.6e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81675.1 - 0.011 15.3 0.6 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Baculo_ME53 PF06061.11 EAX81675.1 - 0.03 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 Trypan_PARP PF05887.11 EAX81676.1 - 0.11 12.5 7.4 0.17 11.9 7.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PRA-PH PF01503.17 EAX81678.1 - 0.19 12.2 2.3 5.1 7.6 3.5 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF2897 PF11446.8 EAX81679.1 - 0.55 10.2 5.3 0.77 9.7 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RNA_polI_A34 PF08208.11 EAX81679.1 - 5.9 6.9 18.9 6 6.9 18.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4108 PF13390.6 EAX81680.1 - 1.3e-54 184.0 7.5 1.5e-54 183.8 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX81681.1 - 4.2e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81682.1 - 2.6e-40 136.8 0.6 5.8e-40 135.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX81682.1 - 0.0096 15.2 0.2 0.035 13.3 0.1 1.8 1 1 1 2 2 2 1 Acyl transferase FAM76 PF16046.5 EAX81682.1 - 0.13 11.6 1.0 0.15 11.4 1.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF3839 PF12943.7 EAX81684.1 - 9.8e-59 198.7 3.6 1.1e-58 198.6 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) rve PF00665.26 EAX81685.1 - 0.0046 17.1 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF3746 PF12562.8 EAX81685.1 - 0.35 10.8 1.8 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) VirE PF05272.11 EAX81687.1 - 9.3e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Virulence-associated protein E DUF4049 PF13258.6 EAX81687.1 - 0.026 13.6 0.9 0.038 13.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RNA_helicase PF00910.22 EAX81687.1 - 0.053 13.9 0.1 0.097 13.1 0.1 1.6 1 1 0 1 1 1 0 RNA helicase DUF4108 PF13390.6 EAX81688.1 - 9.8e-57 190.9 6.5 1.1e-56 190.7 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX81690.1 - 3.7e-05 24.0 0.1 0.00024 21.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81690.1 - 9.6e-05 22.4 3.0 0.00017 21.7 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX81690.1 - 0.00029 20.6 0.3 1.1 8.9 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX81690.1 - 0.0004 20.2 0.1 0.00055 19.8 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81690.1 - 0.00098 19.0 0.8 0.0031 17.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81690.1 - 0.0086 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX81690.1 - 0.049 13.1 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX81690.1 - 0.073 13.5 0.1 0.43 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX81690.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX81690.1 - 0.08 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_30 PF13604.6 EAX81690.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX81691.1 - 6.1e-153 507.2 12.9 7.7e-153 506.9 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81691.1 - 0.093 12.6 1.0 0.33 10.8 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81691.1 - 1.6 9.2 5.8 2.2 8.8 0.6 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX81692.1 - 8.1e-48 162.0 7.5 9e-48 161.8 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4107 PF13389.6 EAX81696.1 - 2.2e-72 242.5 3.1 3e-72 242.1 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_4 PF13637.6 EAX81697.1 - 4.3e-84 275.9 22.1 2e-14 53.7 0.1 11.7 3 1 9 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX81697.1 - 2e-78 255.7 21.8 2.6e-10 40.3 0.1 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_2 PF12796.7 EAX81697.1 - 5.7e-70 231.9 41.7 3.9e-16 59.4 0.9 7.4 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX81697.1 - 2.8e-62 199.3 28.2 5.9e-07 29.3 0.1 12.6 13 0 0 13 13 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX81697.1 - 1.4e-55 184.6 24.5 5.8e-10 39.2 0.1 8.4 5 2 6 11 11 11 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX81697.1 - 6.1e-39 131.8 4.9 6.1e-39 131.8 4.9 3.5 2 2 1 3 3 3 1 Domain of unknown function (DUF3447) RNase_PH_C PF03725.15 EAX81697.1 - 0.003 17.5 8.3 49 4.0 0.1 7.1 1 1 8 9 9 9 0 3' exoribonuclease family, domain 2 PH_8 PF15409.6 EAX81697.1 - 0.0033 17.7 8.9 18 5.7 0.0 5.7 1 1 2 6 6 6 0 Pleckstrin homology domain HEM4 PF02602.15 EAX81697.1 - 0.0041 16.5 0.3 4.9 6.4 0.0 3.6 1 1 3 5 5 5 2 Uroporphyrinogen-III synthase HemD DUF503 PF04456.12 EAX81697.1 - 0.0093 15.8 3.3 36 4.3 0.0 5.2 2 2 3 6 6 6 0 Protein of unknown function (DUF503) PyocinActivator PF11112.8 EAX81697.1 - 0.025 14.7 0.0 30 4.8 0.0 3.9 4 0 0 4 4 4 0 Pyocin activator protein PrtN MTES_1575 PF18741.1 EAX81697.1 - 0.031 14.4 2.6 53 4.1 0.0 5.1 3 2 4 7 7 7 0 REase_MTES_1575 WPP PF13943.6 EAX81697.1 - 0.088 13.2 2.6 4.3 7.8 0.0 3.7 3 1 2 5 5 4 0 WPP domain B PF02216.16 EAX81697.1 - 0.18 11.8 7.4 10 6.2 0.3 4.6 4 0 0 4 4 4 0 B domain ThiS-like PF14453.6 EAX81697.1 - 0.37 10.9 11.0 23 5.1 0.6 4.9 2 2 3 5 5 5 0 ThiS-like ubiquitin DUF5006 PF16397.5 EAX81697.1 - 0.44 9.7 7.7 3.8 6.6 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5006) Minor_capsid_3 PF12691.7 EAX81697.1 - 0.6 10.5 4.9 12 6.3 0.2 3.7 1 1 1 2 2 2 0 Minor capsid protein from bacteriophage DUF3895 PF13034.6 EAX81697.1 - 1.4 9.0 10.9 41 4.3 0.0 6.5 3 3 5 9 9 9 0 Protein of unknown function (DUF3895) Ank_4 PF13637.6 EAX81698.1 - 3.5e-09 37.0 0.3 4.5e-05 23.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX81698.1 - 2.8e-08 33.9 0.1 3.5e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX81698.1 - 4.7e-07 30.0 1.8 0.018 15.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX81698.1 - 4.3e-06 27.2 0.6 8.7e-06 26.2 0.4 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX81698.1 - 0.00027 21.1 0.9 0.016 15.7 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 EAX81699.1 - 1.3e-36 124.4 6.8 1.3e-36 124.4 6.8 5.3 3 1 2 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX81699.1 - 9.5e-36 122.3 26.0 3.1e-14 53.3 1.2 5.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX81699.1 - 3.8e-34 116.6 11.6 1.2e-10 41.7 0.1 7.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX81699.1 - 2.8e-26 88.7 15.6 0.00015 21.9 0.0 9.1 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 EAX81699.1 - 2.8e-21 74.9 14.9 3.6e-05 24.0 0.0 7.8 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX81699.1 - 3.1e-18 65.6 7.2 1.5e-06 28.3 0.3 6.5 3 2 1 6 6 6 4 Ankyrin repeats (many copies) Gly-zipper_Omp PF13488.6 EAX81707.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX81707.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX81707.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Csm2_III-A PF03750.13 EAX81708.1 - 0.023 15.5 0.4 0.027 15.3 0.4 1.1 1 0 0 1 1 1 0 Csm2 Type III-A Spo12 PF05032.12 EAX81708.1 - 0.32 10.9 7.7 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX81709.1 - 9.7e-153 506.5 12.6 1.2e-152 506.2 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX81709.1 - 0.0073 16.0 3.1 0.015 15.0 0.3 2.6 2 2 0 2 2 2 1 Proteasome activator pa28 beta subunit FKBP_N PF01346.18 EAX81709.1 - 0.13 13.3 3.0 0.31 12.0 0.4 2.4 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2408 PF10303.9 EAX81709.1 - 0.29 11.7 2.8 1.5 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX81709.1 - 2.4 8.7 6.4 1.6 9.2 0.2 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX81709.1 - 6.4 7.2 5.9 1.4 9.3 1.1 2.4 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF257 PF03192.13 EAX81710.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX81710.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p T5orf172 PF10544.9 EAX81711.1 - 5.4e-07 30.1 0.5 1.7e-06 28.5 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX81711.1 - 0.0039 16.7 0.2 0.055 13.0 0.0 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX81712.1 - 1e-12 47.9 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX81713.1 - 3.1e-35 120.4 0.6 6.5e-35 119.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81713.1 - 0.0037 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) LOH1CR12 PF10158.9 EAX81713.1 - 0.77 9.8 4.2 1.7 8.7 0.3 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX81714.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX81714.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pox_A32 PF04665.12 EAX81716.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81716.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81716.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81716.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81716.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81716.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81716.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81716.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81716.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81716.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81716.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81716.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX81717.1 - 3.1e-42 142.9 0.7 6.2e-42 142.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81717.1 - 0.013 16.1 0.1 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF4108 PF13390.6 EAX81719.1 - 3.2e-53 179.5 7.8 3.6e-53 179.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX81721.1 - 2.8e-156 518.1 11.2 3.4e-156 517.8 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX81721.1 - 0.86 10.2 5.4 0.25 11.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX81722.1 - 1.6e-72 242.9 3.3 2.1e-72 242.5 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX81723.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX81724.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Cornifin PF02389.15 EAX81725.1 - 0.0094 16.2 1.1 0.011 15.9 1.1 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF2939 PF11159.8 EAX81725.1 - 0.01 16.2 0.5 0.01 16.2 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) PadR PF03551.14 EAX81726.1 - 0.13 12.2 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Renin_r PF07850.14 EAX81728.1 - 0.021 15.4 0.2 17 6.1 0.0 3.9 2 2 1 3 3 3 0 Renin receptor-like protein GET2 PF08690.10 EAX81728.1 - 0.034 13.8 4.0 1.1 8.8 0.1 2.9 2 1 1 3 3 3 0 GET complex subunit GET2 CTD PF12815.7 EAX81729.1 - 0.023 15.2 0.5 0.029 14.9 0.5 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Keratin_B2_2 PF13885.6 EAX81729.1 - 0.25 11.3 16.6 6 6.9 16.6 2.1 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein DUF4108 PF13390.6 EAX81730.1 - 2.5e-60 202.6 8.2 2.7e-60 202.4 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX81732.1 - 6.9e-05 23.3 0.1 0.00016 22.1 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81732.1 - 0.017 14.6 0.4 0.087 12.3 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX81732.1 - 0.024 14.5 0.1 0.066 13.1 0.1 1.9 1 1 0 1 1 1 0 KilA-N domain DUF2960 PF11173.8 EAX81735.1 - 0.03 14.8 0.3 0.077 13.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) MULE PF10551.9 EAX81735.1 - 0.035 14.5 3.0 0.096 13.1 0.1 3.0 3 1 1 4 4 4 0 MULE transposase domain DUF3839 PF12943.7 EAX81736.1 - 1.2e-156 519.4 13.9 1.5e-156 519.0 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81736.1 - 0.25 11.2 1.5 0.76 9.6 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX81736.1 - 0.34 11.5 5.0 0.51 10.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX81736.1 - 0.46 11.0 5.3 5.2 7.6 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX81737.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81737.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81738.1 - 0.1 12.6 9.7 0.16 12.0 9.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_47 PF01532.20 EAX81739.1 - 1e-115 387.3 0.1 1.2e-115 387.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GPS2_interact PF15784.5 EAX81741.1 - 0.026 14.9 1.5 0.035 14.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81741.1 - 0.093 11.7 0.1 0.088 11.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Utp12 PF04003.12 EAX81742.1 - 0.02 15.2 0.5 0.078 13.3 0.1 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family PK_C PF02887.16 EAX81743.1 - 0.00018 21.7 19.2 13 6.1 0.6 8.1 3 2 2 5 5 5 3 Pyruvate kinase, alpha/beta domain LDB19 PF13002.7 EAX81743.1 - 0.14 11.9 5.6 63 3.2 0.1 4.4 3 1 1 4 4 4 0 Arrestin_N terminal like HTH_24 PF13412.6 EAX81743.1 - 1.9 8.1 20.6 11 5.7 0.1 7.1 8 0 0 8 8 8 0 Winged helix-turn-helix DNA-binding BORG_CEP PF14957.6 EAX81743.1 - 6.2 8.0 44.2 9.1 7.5 4.8 5.9 3 1 1 4 4 4 0 Cdc42 effector KilA-N PF04383.13 EAX81745.1 - 1.9e-39 133.9 0.4 1.9e-39 133.9 0.4 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81745.1 - 0.032 14.4 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Peptidase_S10 PF00450.22 EAX81745.1 - 0.074 12.4 3.2 0.031 13.7 0.5 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase ABC1 PF03109.16 EAX81745.1 - 0.085 13.0 0.2 0.32 11.2 0.1 2.0 1 1 0 1 1 1 0 ABC1 family T5orf172 PF10544.9 EAX81746.1 - 8.4e-07 29.5 0.2 1.6e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX81747.1 - 1.7e-155 515.5 13.1 2.2e-155 515.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX81748.1 - 6.5e-23 80.7 0.3 1.3e-22 79.8 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX81748.1 - 0.051 13.5 1.1 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NTS PF15447.6 EAX81748.1 - 0.26 11.8 2.7 5.8 7.5 1.1 2.6 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 MULE PF10551.9 EAX81750.1 - 8.7e-05 22.9 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF3839 PF12943.7 EAX81751.1 - 1.7e-145 482.8 14.3 2e-145 482.6 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81751.1 - 0.002 18.6 1.2 0.016 15.7 0.1 2.1 2 0 0 2 2 2 1 Fez1 LD_cluster2 PF18163.1 EAX81751.1 - 0.092 12.3 0.0 0.32 10.5 0.0 2.0 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX81751.1 - 0.17 12.4 5.5 1.5 9.3 0.5 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81751.1 - 9.1 6.7 8.6 10 6.5 0.1 3.9 3 2 0 3 3 3 0 Tup N-terminal DUF285 PF03382.14 EAX81752.1 - 0.061 13.1 0.5 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF5624 PF18538.1 EAX81752.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Myb_DNA-binding PF00249.31 EAX81753.1 - 2e-30 104.7 1.3 4.2e-14 52.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX81753.1 - 3.5e-24 84.8 0.2 1.1e-11 44.7 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX81753.1 - 0.00023 21.0 0.9 0.015 15.1 0.0 3.2 2 1 1 3 3 3 1 Myb DNA-binding like DUF4167 PF13763.6 EAX81753.1 - 0.00088 19.4 0.0 0.0024 18.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4167) SLIDE PF09111.10 EAX81753.1 - 0.0041 17.1 0.1 0.46 10.5 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_2 PF08914.11 EAX81753.1 - 0.011 15.8 0.7 0.49 10.6 0.3 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX81753.1 - 0.02 15.2 0.2 2.2 8.7 0.0 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX81753.1 - 0.081 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Sigma70_r4_2 PF08281.12 EAX81753.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Peptidase_C14 PF00656.22 EAX81754.1 - 1.1e-06 28.8 0.7 8.3e-06 25.9 0.7 1.9 1 1 0 1 1 1 1 Caspase domain Amidase02_C PF12123.8 EAX81756.1 - 0.0057 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX81757.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FAR1 PF03101.15 EAX81758.1 - 0.055 14.2 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Pox_A32 PF04665.12 EAX81759.1 - 0.00018 21.1 2.8 0.00029 20.4 2.8 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81759.1 - 0.0035 17.0 0.2 0.0048 16.6 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81759.1 - 0.035 13.6 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81759.1 - 0.037 13.7 0.2 0.19 11.5 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81759.1 - 0.067 12.9 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81759.1 - 0.13 12.3 0.7 1 9.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX81759.1 - 0.32 11.2 9.1 4.2 7.6 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX81761.1 - 2e-35 121.0 0.8 3.7e-35 120.2 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81762.1 - 7.2e-07 29.7 0.2 1.5e-06 28.7 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX81762.1 - 0.067 13.9 0.3 0.18 12.5 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF4107 PF13389.6 EAX81763.1 - 6.7e-66 221.4 12.9 3.2e-64 216.0 12.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81767.1 - 1.7e-135 450.1 8.9 2e-135 449.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX81767.1 - 0.043 14.0 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 Z1 PF10593.9 EAX81767.1 - 0.053 13.0 0.7 0.076 12.5 0.7 1.5 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX81767.1 - 0.27 11.9 1.9 0.63 10.7 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF4416 PF14385.6 EAX81769.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) GPS2_interact PF15784.5 EAX81769.1 - 0.076 13.5 1.1 0.1 13.1 1.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX81770.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81770.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin T5orf172 PF10544.9 EAX81771.1 - 5.2e-06 27.0 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81772.1 - 3.8e-41 139.5 0.7 7.6e-41 138.5 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX81772.1 - 0.037 13.2 0.1 0.12 11.6 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase Parathyroid PF01279.17 EAX81772.1 - 0.071 13.7 0.1 0.24 12.1 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX81773.1 - 2.6e-07 31.1 0.4 7.2e-07 29.7 0.4 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81773.1 - 0.015 14.8 1.0 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX81773.1 - 0.016 15.0 0.1 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX81774.1 - 3.5e-157 521.1 12.9 4.5e-157 520.7 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX81774.1 - 0.11 12.8 1.9 13 6.2 0.0 3.4 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX81774.1 - 0.38 11.2 5.5 1.1 9.8 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CREPT PF16566.5 EAX81775.1 - 0.062 13.5 1.3 0.083 13.1 0.1 1.8 2 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX81775.1 - 0.084 12.9 1.0 0.34 10.9 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX81775.1 - 0.1 12.8 6.6 0.39 10.9 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PriX PF18689.1 EAX81775.1 - 0.35 11.2 4.8 1 9.7 0.5 2.7 2 1 0 2 2 2 0 Primase X L27_1 PF09058.10 EAX81775.1 - 0.69 9.9 3.9 5.2 7.1 0.1 2.8 3 0 0 3 3 3 0 L27_1 MapZ_EC1 PF18041.1 EAX81775.1 - 0.94 9.7 5.2 0.25 11.6 1.7 1.8 2 0 0 2 2 2 0 MapZ extracellular domain 1 Peptidase_C74 PF12387.8 EAX81776.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase ARA70 PF12489.8 EAX81777.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF4108 PF13390.6 EAX81778.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX81780.1 - 1.6e-07 31.1 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX81780.1 - 0.088 12.2 0.3 0.17 11.3 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX81781.1 - 1.5e-120 401.1 5.7 1.7e-120 400.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81781.1 - 0.063 12.8 1.0 0.086 12.3 0.5 1.5 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX81781.1 - 0.14 12.6 1.0 1 9.9 0.6 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX81781.1 - 2.3 8.5 4.6 12 6.3 0.1 3.0 2 1 0 2 2 2 0 Rx N-terminal domain DUF4795 PF16043.5 EAX81782.1 - 0.16 11.6 11.8 1 8.9 0.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX81782.1 - 1.5 9.2 9.8 0.4 11.0 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat GPS2_interact PF15784.5 EAX81783.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81783.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain CmcI PF04989.12 EAX81785.1 - 0.095 12.4 0.1 5.9 6.5 0.0 2.0 1 1 1 2 2 2 0 Cephalosporin hydroxylase DUF3839 PF12943.7 EAX81786.1 - 9.5e-158 522.9 12.4 1.1e-157 522.7 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81786.1 - 0.1 12.9 0.7 2.5 8.5 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX81786.1 - 0.11 12.9 4.7 1.8 9.1 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX81786.1 - 0.32 11.3 3.1 13 6.2 0.1 3.5 3 2 1 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX81786.1 - 1.5 9.4 4.4 0.88 10.1 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2121 PF09894.9 EAX81787.1 - 1.7 8.1 6.8 14 5.2 6.8 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) SSP160 PF06933.11 EAX81787.1 - 5.7 5.0 20.1 6.5 4.8 20.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3839 PF12943.7 EAX81789.1 - 3.4e-113 377.1 8.5 4e-113 376.8 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81789.1 - 0.026 14.0 2.1 0.037 13.5 1.8 1.5 1 1 0 1 1 1 0 Z1 domain PSP PF04046.16 EAX81790.1 - 0.065 13.1 0.9 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX81791.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX81793.1 - 1.4e-14 53.9 33.1 1.6e-08 34.5 5.2 5.8 5 1 0 5 5 5 4 Phage tail repeat like MMR_HSR1 PF01926.23 EAX81793.1 - 0.1 12.7 2.8 25 5.0 0.1 3.4 2 1 1 3 3 3 0 50S ribosome-binding GTPase EpuA PF11772.8 EAX81793.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Ribosomal_S4e PF00900.20 EAX81793.1 - 0.13 12.2 1.2 1.1e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 Ribosomal family S4e PapD_N PF00345.20 EAX81794.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX81794.1 - 0.13 12.3 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX81795.1 - 0.021 15.2 0.8 0.031 14.7 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX81795.1 - 1.5 7.8 3.8 1.6 7.7 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX81795.1 - 1.6 8.8 6.6 1.8 8.6 6.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX81796.1 - 0.016 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Myb_DNA-bind_6 PF13921.6 EAX81797.1 - 2.6e-27 94.8 8.0 4.2e-16 58.9 1.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX81797.1 - 1.1e-25 89.5 5.1 1e-13 51.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX81797.1 - 3.9e-06 27.0 2.9 0.0069 16.6 0.6 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX81797.1 - 1.5e-05 24.8 6.6 8.6e-05 22.4 2.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX81797.1 - 0.00024 21.1 3.4 0.041 13.9 0.7 2.8 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX81797.1 - 0.026 14.6 0.0 0.9 9.7 0.0 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.6 EAX81797.1 - 0.047 13.8 8.3 0.49 10.5 0.7 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Peptidase_C33 PF05412.12 EAX81798.1 - 0.007 16.4 3.4 1.4 8.9 0.2 2.1 2 0 0 2 2 2 2 Equine arterivirus Nsp2-type cysteine proteinase DUF3470 PF11953.8 EAX81798.1 - 0.047 13.7 2.9 4.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) 3-alpha PF03475.14 EAX81798.1 - 0.11 12.3 1.3 16 5.5 0.1 2.5 2 0 0 2 2 2 0 3-alpha domain zf-TRAF PF02176.18 EAX81799.1 - 0.0089 16.7 6.3 17 6.2 0.1 3.3 3 0 0 3 3 3 3 TRAF-type zinc finger DUF3470 PF11953.8 EAX81799.1 - 0.038 14.0 8.0 11 6.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) 3-alpha PF03475.14 EAX81799.1 - 0.088 12.7 4.8 34 4.4 0.1 3.4 3 0 0 3 3 3 0 3-alpha domain DUF3939 PF13075.6 EAX81799.1 - 0.19 11.7 0.0 1.3e+02 2.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3939) HNH_2 PF13391.6 EAX81799.1 - 1.4 9.1 8.7 45 4.3 0.2 3.6 3 0 0 3 3 3 0 HNH endonuclease KilA-N PF04383.13 EAX81801.1 - 3.2e-34 117.1 0.7 6.8e-34 116.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81802.1 - 4.2e-07 30.4 0.3 8.3e-07 29.5 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF4090 PF13319.6 EAX81803.1 - 0.0039 17.4 0.1 1.5 9.1 0.0 3.7 1 1 5 6 6 6 1 Protein of unknown function (DUF4090) Keratin_B2 PF01500.17 EAX81803.1 - 0.0068 16.4 4.0 0.016 15.2 4.0 1.6 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein Transketolase_C PF02780.20 EAX81803.1 - 0.022 14.6 4.2 6.2 6.7 0.1 4.2 1 1 3 4 4 4 0 Transketolase, C-terminal domain DUF521 PF04412.13 EAX81803.1 - 0.023 13.4 0.1 0.58 8.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF521) DUF3586 PF12131.8 EAX81803.1 - 0.13 12.5 2.9 7.2 6.9 0.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3586) Inv-AAD PF18785.1 EAX81803.1 - 1.5 8.7 5.9 3 7.7 0.2 3.0 1 1 1 2 2 2 0 Invertebrate-AID/APOBEC-deaminase AMMECR1 PF01871.17 EAX81803.1 - 1.7 8.3 7.9 11 5.6 0.2 3.5 1 1 3 4 4 4 0 AMMECR1 DUF3839 PF12943.7 EAX81805.1 - 1.3e-119 398.1 11.8 1.6e-119 397.8 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81805.1 - 0.0018 18.7 2.2 0.49 10.9 0.0 3.0 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX81805.1 - 0.026 15.0 0.2 0.039 14.4 0.2 1.3 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX81805.1 - 0.085 13.4 1.2 0.15 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX81808.1 - 1.5e-156 519.0 12.1 1.9e-156 518.7 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX81808.1 - 0.14 12.8 3.9 0.49 11.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX81808.1 - 0.46 11.0 6.2 4.2 7.9 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAX81809.1 - 2.9e-52 177.6 0.0 4.8e-52 176.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX81809.1 - 1.1e-33 116.6 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX81809.1 - 0.00021 20.3 0.6 0.00047 19.2 0.6 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX81809.1 - 0.0053 16.7 0.5 0.016 15.1 0.7 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX81809.1 - 0.017 14.4 0.0 0.11 11.8 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EAX81809.1 - 0.036 13.4 0.2 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_A32 PF04665.12 EAX81810.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein zf-C3HC4_3 PF13920.6 EAX81811.1 - 1.9e-07 30.8 6.6 1.9e-07 30.8 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX81811.1 - 5.3e-07 29.4 9.3 5.3e-07 29.4 9.3 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAX81811.1 - 7.9e-07 29.3 9.3 7.9e-07 29.3 9.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAX81811.1 - 2.9e-06 27.1 10.1 7.1e-06 25.8 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX81811.1 - 5.5e-06 26.1 11.0 1.1e-05 25.1 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX81811.1 - 1.3e-05 25.1 5.2 1.3e-05 25.1 5.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX81811.1 - 0.0041 17.1 11.6 0.0041 17.1 11.6 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-Di19 PF05605.12 EAX81811.1 - 0.019 15.3 9.9 0.57 10.5 8.8 2.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-rbx1 PF12678.7 EAX81811.1 - 0.023 15.0 8.6 0.051 13.9 8.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 EAX81811.1 - 0.032 14.0 6.9 0.19 11.5 1.9 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Zn_ribbon_17 PF17120.5 EAX81811.1 - 0.037 13.7 7.9 0.066 12.9 7.2 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_13 PF17977.1 EAX81811.1 - 0.067 13.3 3.6 0.13 12.4 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gin PF10764.9 EAX81811.1 - 0.33 10.9 9.5 5.5 7.0 1.8 3.9 4 0 0 4 4 4 0 Inhibitor of sigma-G Gin zf-Nse PF11789.8 EAX81811.1 - 0.62 9.9 9.5 4.7 7.1 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EAX81811.1 - 0.77 10.0 13.1 2.8 8.2 11.1 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EAX81811.1 - 1.3 8.9 4.6 4.1 7.3 0.1 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-B_box PF00643.24 EAX81811.1 - 1.5 9.0 7.0 6.6 7.0 7.0 2.1 1 1 0 1 1 1 0 B-box zinc finger Zn-ribbon_8 PF09723.10 EAX81811.1 - 1.9 8.7 8.4 5 7.3 3.1 2.8 3 0 0 3 3 2 0 Zinc ribbon domain zf-ANAPC11 PF12861.7 EAX81811.1 - 2.3 8.3 7.7 5.3 7.2 6.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EAX81811.1 - 2.8 7.9 7.6 0.33 10.8 2.9 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 EAX81811.1 - 2.8 8.0 7.8 16 5.6 7.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF1451 PF07295.11 EAX81811.1 - 3.3 7.7 5.0 4.3 7.4 2.4 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain KilA-N PF04383.13 EAX81812.1 - 2.9e-42 143.0 0.4 7e-42 141.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81812.1 - 0.006 17.2 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX81813.1 - 1.2e-06 28.2 2.1 1.2e-06 28.2 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81813.1 - 3.6e-05 24.1 0.2 0.00025 21.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81813.1 - 4.2e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81813.1 - 0.00014 21.9 3.2 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81813.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX81813.1 - 0.0017 18.0 0.5 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX81813.1 - 0.0017 18.2 0.8 0.0053 16.6 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81813.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Epimerase_2 PF02350.19 EAX81813.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase AAA_25 PF13481.6 EAX81813.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX81813.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX81813.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX81813.1 - 0.39 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX81816.1 - 1.7e-21 76.1 46.7 2.2e-11 43.6 5.7 6.0 6 0 0 6 6 6 4 Phage tail repeat like Cas_Csm6 PF09659.10 EAX81816.1 - 6.9e-08 31.7 10.0 0.0027 16.5 2.0 3.3 1 1 1 3 3 3 3 CRISPR-associated protein (Cas_Csm6) PatG_C PF18065.1 EAX81816.1 - 0.01 15.8 0.7 19 5.3 0.0 3.5 3 0 0 3 3 3 0 PatG C-terminal Ribosomal_S4e PF00900.20 EAX81816.1 - 0.014 15.3 0.1 58 3.7 0.0 3.8 3 0 0 3 3 3 0 Ribosomal family S4e RraB PF06877.11 EAX81816.1 - 0.26 12.0 2.4 8.2 7.2 0.1 2.8 2 0 0 2 2 2 0 Regulator of ribonuclease activity B DASH_Dad2 PF08654.10 EAX81817.1 - 2.1e-06 28.0 82.8 0.0059 17.0 1.8 10.9 5 3 5 11 11 11 6 DASH complex subunit Dad2 AAA_13 PF13166.6 EAX81817.1 - 0.00018 20.3 14.8 0.00018 20.3 14.8 4.9 1 1 2 4 4 4 2 AAA domain MobL PF18555.1 EAX81817.1 - 0.0026 17.1 19.1 0.0026 17.1 19.1 4.9 1 1 3 4 4 4 1 MobL relaxases DUF3584 PF12128.8 EAX81817.1 - 0.01 13.4 133.8 0.005 14.4 44.7 4.3 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) APG6_N PF17675.1 EAX81817.1 - 0.012 16.1 21.2 0.012 16.1 21.2 8.8 2 2 6 8 8 8 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 EAX81817.1 - 0.015 15.1 3.5 0.015 15.1 3.5 10.5 1 1 8 9 9 9 0 Phage minor structural protein GP20 FUSC PF04632.12 EAX81817.1 - 0.46 9.0 23.9 2 6.9 3.1 3.3 1 1 2 3 3 3 0 Fusaric acid resistance protein family AA_permease_N PF08403.10 EAX81817.1 - 0.89 9.1 4.4 1.4 8.4 0.1 3.7 3 0 0 3 3 3 0 Amino acid permease N-terminal DUF4407 PF14362.6 EAX81817.1 - 8.9 5.6 109.9 0.19 11.1 9.1 5.9 1 1 5 6 6 6 0 Domain of unknown function (DUF4407) PTR PF12789.7 EAX81818.1 - 3.3e-17 62.3 28.1 2.2e-08 34.0 5.1 5.4 5 0 0 5 5 5 4 Phage tail repeat like EMP24_GP25L PF01105.24 EAX81818.1 - 0.032 14.2 4.0 8 6.4 2.0 3.4 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD EpuA PF11772.8 EAX81818.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF2120 PF09893.9 EAX81818.1 - 0.26 11.4 1.7 4.3 7.4 0.2 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) IL2 PF00715.17 EAX81818.1 - 0.72 9.8 3.0 27 4.7 0.0 2.8 3 0 0 3 3 3 0 Interleukin 2 DUF4107 PF13389.6 EAX81820.1 - 4.8e-66 221.9 13.2 1.4e-64 217.2 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81820.1 - 0.097 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX81827.1 - 1.5e-24 86.8 8.6 1.3e-23 83.6 7.8 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX81827.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DNA_pol_B_2 PF03175.13 EAX81828.1 - 1.3e-37 129.8 14.9 2.9e-37 128.7 14.9 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX81828.1 - 0.26 11.4 1.5 10 6.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) T5orf172 PF10544.9 EAX81829.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain Lipid_DES PF08557.10 EAX81830.1 - 0.21 11.1 1.0 0.77 9.3 1.0 2.0 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) DUF4108 PF13390.6 EAX81832.1 - 8.1e-58 194.4 8.9 9e-58 194.3 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX81832.1 - 0.11 12.7 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX81833.1 - 2.2e-151 502.1 12.9 2.7e-151 501.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX81833.1 - 0.083 13.3 0.4 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX81833.1 - 0.9 10.0 7.6 2.5 8.6 0.8 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX81834.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4795 PF16043.5 EAX81835.1 - 0.0029 17.3 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Glyco_transf_49 PF13896.6 EAX81835.1 - 0.0094 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Phage_fiber PF03335.13 EAX81835.1 - 1.3 9.4 9.8 0.38 11.0 1.9 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF4108 PF13390.6 EAX81836.1 - 5.9e-58 194.8 7.4 6.9e-58 194.6 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) EF-hand_4 PF12763.7 EAX81836.1 - 0.036 14.0 0.6 0.063 13.2 0.2 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 EAX81837.1 - 3.4e-35 121.1 0.0 3.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX81837.1 - 6.7e-27 94.1 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX81837.1 - 6.7e-10 38.7 0.0 8.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX81837.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX81837.1 - 0.014 15.3 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EAX81837.1 - 0.017 14.4 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EAX81837.1 - 0.048 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EAX81837.1 - 0.059 13.4 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3839 PF12943.7 EAX81838.1 - 1.6e-156 518.9 12.5 2e-156 518.6 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81838.1 - 2.8 8.4 7.3 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX81839.1 - 3.4e-07 30.8 0.3 6.1e-07 29.9 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX81839.1 - 0.12 13.1 0.4 0.36 11.5 0.4 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Pox_A32 PF04665.12 EAX81840.1 - 4.2e-07 29.7 3.3 4.8e-07 29.5 1.6 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81840.1 - 1.9e-05 24.9 0.2 0.00019 21.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81840.1 - 9.8e-05 22.4 2.7 0.00021 21.4 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81840.1 - 0.00014 21.7 0.1 0.00027 20.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EAX81840.1 - 0.00015 21.6 0.3 0.41 10.4 0.0 2.8 2 2 1 3 3 3 2 IstB-like ATP binding protein AAA_11 PF13086.6 EAX81840.1 - 0.001 18.9 1.0 0.0019 18.1 1.0 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81840.1 - 0.0023 17.6 0.6 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81840.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain NIBRIN_BRCT_II PF16508.5 EAX81840.1 - 0.06 13.7 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_25 PF13481.6 EAX81840.1 - 0.079 12.5 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX81840.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81840.1 - 0.34 11.2 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX81841.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX81842.1 - 2.1e-10 40.5 21.6 7.5e-09 35.5 4.9 4.1 4 0 0 4 4 4 2 Phage tail repeat like Ribosomal_S4e PF00900.20 EAX81842.1 - 0.11 12.4 0.1 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Ribosomal family S4e KilA-N PF04383.13 EAX81843.1 - 6.3e-31 106.5 0.3 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX81846.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF563 PF04577.14 EAX81847.1 - 8.2e-33 114.3 0.2 1.3e-32 113.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FliJ PF02050.16 EAX81848.1 - 0.03 14.5 0.1 0.037 14.2 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein GPS2_interact PF15784.5 EAX81849.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81849.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81850.1 - 0.069 13.1 13.0 0.072 13.1 13.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81850.1 - 2.7 8.4 6.6 3 8.3 6.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 EAX81851.1 - 0.053 13.5 10.2 0.074 13.0 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX81852.1 - 0.0099 15.5 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX81853.1 - 7.7e-07 28.8 0.1 2e-06 27.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX81855.1 - 1.8e-155 515.5 13.2 2.2e-155 515.2 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LZ3wCH PF18517.1 EAX81855.1 - 0.1 12.7 3.3 0.11 12.6 0.4 2.6 2 0 0 2 2 2 0 Leucine zipper with capping helix domain NTP_transf_6 PF06042.11 EAX81855.1 - 0.2 11.5 1.5 0.49 10.2 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase L1R_F9L PF02442.17 EAX81856.1 - 0.061 13.2 0.1 0.062 13.1 0.1 1.0 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Drf_FH1 PF06346.12 EAX81858.1 - 2.4e-06 27.3 39.5 0.00091 19.0 20.7 2.6 1 1 1 2 2 2 2 Formin Homology Region 1 Tho2 PF11262.8 EAX81859.1 - 0.12 11.5 3.5 0.13 11.4 3.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAS_N PF17828.1 EAX81860.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX81861.1 - 0.037 14.5 0.3 0.063 13.7 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) DUF3839 PF12943.7 EAX81862.1 - 3.4e-157 521.1 13.9 4.4e-157 520.8 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81862.1 - 0.15 11.9 1.5 0.51 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX81862.1 - 4.6 7.8 6.9 3.7 8.1 0.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2689 PF10894.8 EAX81864.1 - 0.016 15.0 0.9 3.1 7.6 0.1 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF2689) DUF3653 PF12375.8 EAX81864.1 - 0.016 15.3 3.4 2.8 8.1 0.3 3.8 2 1 2 4 4 4 0 Phage protein MORN_2 PF07661.13 EAX81864.1 - 0.046 13.9 0.0 50 4.6 0.0 3.9 5 0 0 5 5 5 0 MORN repeat variant Autophagy_N PF03986.13 EAX81864.1 - 0.085 12.8 8.3 2.3 8.2 0.0 3.9 2 2 2 4 4 4 0 Autophagocytosis associated protein (Atg3), N-terminal domain Glyco_hydro_65C PF03633.15 EAX81864.1 - 1.6 8.7 6.3 63 3.6 0.1 3.6 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain KilA-N PF04383.13 EAX81865.1 - 3.2e-32 110.7 0.4 7.7e-32 109.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81866.1 - 1.5e-156 519.0 12.6 1.8e-156 518.7 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81866.1 - 0.015 15.7 2.2 0.065 13.7 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81866.1 - 0.56 10.7 7.3 1.6 9.2 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81866.1 - 0.66 10.5 6.6 0.25 11.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX81868.1 - 2.5e-07 30.4 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81868.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81868.1 - 0.046 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81868.1 - 0.064 13.0 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81868.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81868.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX81868.1 - 0.5 10.6 8.3 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX81869.1 - 1.7e-78 263.4 5.5 1.9e-78 263.3 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81869.1 - 0.056 12.9 0.2 0.061 12.8 0.2 1.1 1 0 0 1 1 1 0 Z1 domain Glu-tRNAGln PF02686.15 EAX81869.1 - 0.13 12.6 1.3 0.35 11.2 1.4 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DDR PF08841.10 EAX81871.1 - 0.096 11.7 0.1 0.097 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX81872.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Arm-DNA-bind_5 PF17293.2 EAX81873.1 - 0.00099 19.5 1.9 0.00099 19.5 1.9 2.2 2 1 0 2 2 2 1 Arm DNA-binding domain Allexi_40kDa PF05549.11 EAX81873.1 - 0.073 12.6 3.5 0.081 12.4 3.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Hrs_helical PF12210.8 EAX81873.1 - 0.17 12.4 6.7 0.83 10.2 3.1 2.1 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Enkurin PF13864.6 EAX81873.1 - 0.61 10.6 10.4 0.82 10.1 10.4 1.2 1 0 0 1 1 1 0 Calmodulin-binding KilA-N PF04383.13 EAX81875.1 - 3.7e-43 145.9 0.7 7.1e-43 145.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81875.1 - 0.03 14.5 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX81876.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81876.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81876.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81876.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81876.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81876.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81876.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81876.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81876.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81876.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81876.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81876.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX81877.1 - 1.4e-157 522.4 13.5 1.8e-157 522.1 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX81877.1 - 0.15 11.9 1.3 0.45 10.4 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX81877.1 - 0.55 10.5 2.8 2.4 8.5 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX81877.1 - 3.2 8.3 7.4 2.1 8.9 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81878.1 - 7.3e-155 513.5 11.8 8.8e-155 513.2 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX81878.1 - 0.012 15.9 1.2 1.1 9.6 0.1 3.3 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX81878.1 - 0.14 12.0 0.8 0.6 9.9 0.7 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase BACK PF07707.15 EAX81879.1 - 0.00032 20.8 1.6 0.00035 20.6 1.6 1.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch SmaI PF17411.2 EAX81879.1 - 0.021 14.0 0.3 0.021 14.0 0.3 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease DUF3839 PF12943.7 EAX81881.1 - 3.3e-127 422.9 7.2 3.8e-127 422.7 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81881.1 - 0.058 12.9 1.2 0.088 12.3 0.5 1.5 1 1 1 2 2 2 0 Z1 domain KELK PF15796.5 EAX81881.1 - 0.08 13.4 0.9 1 9.8 0.5 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX81881.1 - 0.11 12.8 4.4 1.2 9.5 0.0 3.1 2 1 0 2 2 2 0 Rx N-terminal domain DUF5398 PF17376.2 EAX81881.1 - 0.26 11.9 1.8 0.6 10.8 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Clathrin PF00637.20 EAX81882.1 - 3.4e-23 82.1 2.3 1.7e-20 73.3 0.6 2.4 1 1 1 2 2 2 2 Region in Clathrin and VPS TPR_7 PF13176.6 EAX81882.1 - 0.012 15.6 0.6 0.25 11.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CARD_2 PF16739.5 EAX81882.1 - 0.041 13.9 0.5 1.8 8.6 0.0 3.1 2 1 1 3 3 3 0 Caspase recruitment domain Myb_DNA-bind_6 PF13921.6 EAX81882.1 - 0.085 13.1 0.4 0.37 11.1 0.0 2.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Ribonuc_2-5A PF06479.12 EAX81882.1 - 0.088 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A TPR_2 PF07719.17 EAX81882.1 - 0.12 12.6 0.1 0.46 10.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Clathrin_propel PF01394.20 EAX81883.1 - 8.8e-05 22.6 0.1 0.1 12.9 0.1 3.8 3 0 0 3 3 3 2 Clathrin propeller repeat DUF5114 PF17141.4 EAX81883.1 - 0.078 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) T5orf172 PF10544.9 EAX81884.1 - 1e-06 29.2 0.2 3e-06 27.7 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81884.1 - 0.012 15.4 0.5 0.071 13.0 0.1 2.2 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX81884.1 - 0.036 13.6 1.2 0.18 11.3 0.5 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX81885.1 - 1.1e-70 237.8 5.6 1.3e-70 237.6 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81885.1 - 0.027 15.0 0.3 0.033 14.6 0.3 1.1 1 0 0 1 1 1 0 Fez1 P4Ha_N PF08336.11 EAX81885.1 - 0.028 14.4 0.7 6.4 6.8 0.2 2.2 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2408 PF10303.9 EAX81885.1 - 0.084 13.4 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 EAX81885.1 - 0.12 11.6 0.4 0.14 11.4 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein TMP PF05017.14 EAX81888.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX81889.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX81890.1 - 9e-42 141.5 0.7 2.2e-41 140.2 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX81891.1 - 3.9e-119 396.5 11.3 4.9e-119 396.2 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81891.1 - 0.0034 17.8 1.5 1.5 9.4 0.0 3.0 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase P4Ha_N PF08336.11 EAX81891.1 - 0.019 15.0 0.6 3 7.9 0.2 2.5 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region THOC7 PF05615.13 EAX81891.1 - 0.089 13.1 0.7 0.22 11.8 0.7 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2408 PF10303.9 EAX81891.1 - 0.13 12.8 1.7 0.2 12.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX81891.1 - 0.15 11.6 0.2 1.1 8.7 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 Pox_A32 PF04665.12 EAX81892.1 - 5.1e-07 29.4 1.2 5.1e-07 29.4 1.2 1.9 2 2 1 3 3 3 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX81892.1 - 3.1e-05 23.8 0.3 0.29 10.9 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX81892.1 - 4.9e-05 23.6 0.2 0.00034 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81892.1 - 0.00036 20.6 4.0 0.00084 19.4 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81892.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81892.1 - 0.0019 18.0 0.8 0.0033 17.2 0.4 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81892.1 - 0.0036 17.0 2.5 0.016 14.9 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81892.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX81892.1 - 0.092 12.3 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX81892.1 - 0.1 12.6 0.7 1.6 8.8 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX81892.1 - 0.21 11.9 4.1 3.9 7.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX81892.1 - 0.52 11.0 10.7 0.5 11.0 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF4107 PF13389.6 EAX81893.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81895.1 - 5.9e-157 520.3 12.7 7.5e-157 520.0 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX81895.1 - 0.035 14.6 2.3 0.15 12.5 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX81895.1 - 0.51 10.8 7.4 2.1 8.9 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX81895.1 - 1.2 9.7 7.9 0.22 12.1 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) CREPT PF16566.5 EAX81896.1 - 0.033 14.3 0.2 0.081 13.1 0.2 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX81896.1 - 0.77 9.9 5.7 0.33 11.1 1.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DDE_Tnp_ISL3 PF01610.17 EAX81897.1 - 0.03 14.0 0.2 0.052 13.3 0.1 1.5 2 0 0 2 2 2 0 Transposase PTR PF12789.7 EAX81902.1 - 1.6e-09 37.7 10.9 1.7e-08 34.4 5.8 4.3 5 0 0 5 5 5 2 Phage tail repeat like GIT1_C PF12205.8 EAX81902.1 - 0.045 13.9 0.9 6.1 7.0 0.2 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term LIFR_D2 PF17971.1 EAX81902.1 - 0.14 12.4 0.0 14 5.9 0.0 2.3 1 1 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX81902.1 - 0.16 11.9 1.6 9.1 6.2 0.1 2.5 2 1 0 2 2 2 0 Interleukin 2 KilA-N PF04383.13 EAX81903.1 - 2.2e-34 117.6 0.5 5.4e-34 116.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX81903.1 - 0.059 14.1 1.5 12 6.7 0.3 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 T5orf172 PF10544.9 EAX81904.1 - 4e-06 27.3 0.2 7.7e-06 26.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF5623 PF18536.1 EAX81905.1 - 0.02 15.1 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX81905.1 - 0.43 10.5 8.0 0.15 12.0 2.9 2.2 2 0 0 2 2 2 0 Spo12 family T5orf172 PF10544.9 EAX81906.1 - 7.8e-07 29.6 0.2 2.2e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX81906.1 - 0.018 14.6 1.2 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX81906.1 - 0.023 14.5 1.9 0.074 12.9 0.5 2.4 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX81907.1 - 4.8e-157 520.6 14.2 6e-157 520.3 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX81907.1 - 0.27 11.6 4.0 13 6.2 0.0 3.7 4 1 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX81907.1 - 0.81 10.2 7.3 0.76 10.3 0.1 3.4 3 2 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX81908.1 - 4.3e-16 58.8 1.4 5.1e-16 58.6 1.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX81909.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein T5orf172 PF10544.9 EAX81910.1 - 5.4e-07 30.1 0.2 1e-06 29.2 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81911.1 - 4.9e-33 113.3 1.7 5.1e-33 113.3 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81911.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX81911.1 - 0.0069 16.8 4.9 0.26 11.7 1.1 2.5 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 DUF3653 PF12375.8 EAX81912.1 - 0.031 14.4 1.5 11 6.2 0.0 3.0 2 1 0 3 3 3 0 Phage protein SHIPPO-rpt PF07004.12 EAX81912.1 - 0.08 13.9 8.1 4.2 8.4 0.7 3.6 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat Pox_A32 PF04665.12 EAX81913.1 - 5.2e-08 32.6 1.0 6.3e-08 32.4 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81913.1 - 0.004 16.8 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX81913.1 - 0.053 13.2 0.0 0.099 12.4 0.0 1.4 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX81913.1 - 0.08 12.9 0.3 0.71 9.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX81913.1 - 0.14 12.6 1.5 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF4108 PF13390.6 EAX81914.1 - 2.3e-57 192.9 4.2 2.5e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX81915.1 - 1.1 9.2 4.2 2.2 8.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX81916.1 - 3.6e-07 29.9 2.7 3.6e-07 29.9 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81916.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX81916.1 - 0.00016 21.7 3.0 0.00037 20.5 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX81916.1 - 0.00023 20.9 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX81916.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81916.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81916.1 - 0.0013 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81916.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX81916.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX81916.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX81916.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 EAX81917.1 - 1.6e-41 140.8 12.4 3.3e-14 53.2 1.4 5.1 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX81917.1 - 4.6e-41 137.5 3.1 1.5e-06 28.4 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX81917.1 - 2.4e-40 136.4 3.3 7.1e-08 32.9 0.0 7.6 3 2 6 9 9 9 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX81917.1 - 3e-37 126.4 6.1 3e-37 126.4 6.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX81917.1 - 1e-29 99.3 7.9 0.002 18.4 0.0 8.4 8 1 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX81917.1 - 6.3e-25 86.9 0.2 3.2e-08 33.7 0.0 5.1 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Stap_Strp_toxin PF01123.20 EAX81917.1 - 0.0018 19.1 4.8 13 6.7 0.1 4.6 1 1 4 5 5 5 1 Staphylococcal/Streptococcal toxin, OB-fold domain Rop PF01815.16 EAX81917.1 - 0.0045 16.8 0.1 1.1e+02 2.8 0.0 4.3 4 0 0 4 4 4 0 Rop protein DUF4760 PF15956.5 EAX81917.1 - 0.014 15.6 4.3 1.6 8.8 1.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) Topo_Zn_Ribbon PF08272.11 EAX81917.1 - 0.034 13.8 2.5 18 5.1 0.0 4.2 5 0 0 5 5 5 0 Topoisomerase I zinc-ribbon-like YkuD_2 PF13645.6 EAX81917.1 - 0.041 13.3 1.4 2.8 7.4 0.1 3.5 1 1 4 5 5 5 0 L,D-transpeptidase catalytic domain PH_8 PF15409.6 EAX81917.1 - 0.13 12.5 4.2 61 4.0 0.1 4.2 1 1 3 4 4 4 0 Pleckstrin homology domain SAB PF04382.13 EAX81917.1 - 1.3 9.1 7.8 65 3.7 0.1 4.8 5 0 0 5 5 5 0 SAB domain Gly-zipper_Omp PF13488.6 EAX81918.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX81918.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX81918.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4625 PF15418.6 EAX81920.1 - 0.00052 20.3 0.3 0.0083 16.4 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) Cohesin PF00963.18 EAX81920.1 - 0.00097 19.4 2.1 0.00097 19.4 2.1 2.0 1 1 1 2 2 2 1 Cohesin domain Big_9 PF17963.1 EAX81920.1 - 0.003 18.3 2.2 2.1 9.1 0.1 2.2 2 0 0 2 2 2 2 Bacterial Ig domain ChitinaseA_N PF08329.10 EAX81920.1 - 0.0056 16.3 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Chitinase A, N-terminal domain DUF4832 PF16116.5 EAX81920.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) MG2 PF01835.19 EAX81920.1 - 0.023 15.1 0.1 0.057 13.9 0.0 1.6 2 0 0 2 2 2 0 MG2 domain NPCBM_assoc PF10633.9 EAX81920.1 - 0.032 14.5 0.3 0.095 13.0 0.2 1.9 1 1 1 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase BACON PF13004.7 EAX81920.1 - 0.048 13.7 0.6 0.16 12.0 0.7 1.9 1 1 1 2 2 2 0 Putative binding domain, N-terminal DUF2914 PF11141.8 EAX81920.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2914) He_PIG PF05345.12 EAX81920.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative Ig domain T5orf172 PF10544.9 EAX81921.1 - 7.4e-07 29.7 0.2 1.9e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX81922.1 - 2e-38 130.7 1.5 3e-38 130.1 0.4 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX81922.1 - 0.059 14.0 0.3 0.2 12.3 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family PTR PF12789.7 EAX81923.1 - 3.2e-08 33.5 21.3 1.1e-07 31.8 1.6 5.8 6 2 1 7 7 7 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX81923.1 - 0.39 10.6 4.0 4.6 7.1 0.1 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4795 PF16043.5 EAX81923.1 - 2.3 7.8 14.6 0.25 10.9 7.2 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Mito_fiss_reg PF05308.11 EAX81924.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX81924.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pox_A32 PF04665.12 EAX81928.1 - 4.8e-07 29.5 3.2 4.8e-07 29.5 3.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81928.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81928.1 - 4.6e-05 23.2 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81928.1 - 0.00014 21.9 3.4 0.00032 20.8 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81928.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX81928.1 - 0.00092 18.9 0.6 0.0051 16.5 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX81928.1 - 0.0011 18.8 0.7 0.002 17.9 0.7 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX81928.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 EAX81928.1 - 0.027 14.2 0.5 0.041 13.5 0.5 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX81928.1 - 0.071 12.7 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX81928.1 - 0.086 13.3 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81928.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX81928.1 - 0.33 11.2 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Cytomega_UL84 PF06284.11 EAX81929.1 - 4.8 5.5 7.1 6.1 5.2 7.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Flavodoxin_2 PF02525.17 EAX81931.1 - 8.7e-26 90.8 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX81931.1 - 8.6e-05 22.3 0.0 0.00051 19.8 0.0 2.0 1 1 0 1 1 1 1 NADPH-dependent FMN reductase TfoX_N PF04993.13 EAX81931.1 - 0.05 13.8 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 TfoX N-terminal domain Chal_sti_synt_N PF00195.19 EAX81932.1 - 0.047 13.1 0.6 0.092 12.2 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX81933.1 - 5.2e-155 514.0 12.8 6.2e-155 513.7 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX81933.1 - 0.38 11.3 2.7 2.4 8.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX81934.1 - 2.4e-45 153.0 0.9 4.4e-45 152.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX81934.1 - 0.031 14.5 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX81935.1 - 1.1e-06 28.3 2.3 1.1e-06 28.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX81935.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX81935.1 - 7.2e-05 22.6 0.2 0.4 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX81935.1 - 0.00011 22.2 2.8 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX81935.1 - 0.00063 19.6 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX81935.1 - 0.0013 18.6 0.4 0.0032 17.3 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX81935.1 - 0.0019 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX81935.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX81935.1 - 0.071 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX81935.1 - 0.087 13.3 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX81935.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX81935.1 - 0.14 12.6 2.8 0.72 10.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX81935.1 - 0.38 11.0 3.7 12 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) FliD_N PF02465.18 EAX81937.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX81937.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YvrJ PF12841.7 EAX81938.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family DUF4107 PF13389.6 EAX81939.1 - 1.8e-65 220.0 13.2 8.8e-64 214.5 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX81941.1 - 8.6e-155 513.2 13.2 1.1e-154 512.9 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX81941.1 - 0.18 12.1 2.1 0.54 10.6 0.2 2.6 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX81941.1 - 0.39 11.2 4.5 11 6.6 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX81942.1 - 2.6e-11 43.4 0.2 5.2e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX81942.1 - 0.24 10.8 0.3 0.59 9.5 0.3 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Peptidase_M8 PF01457.16 EAX81943.1 - 6.7e-26 91.1 0.1 4.8e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 Leishmanolysin Mid2 PF04478.12 EAX81943.1 - 0.0042 16.9 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX81943.1 - 0.025 14.6 3.9 0.059 13.4 3.9 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Protocadherin PF08374.11 EAX81943.1 - 0.2 11.6 1.5 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 Protocadherin Phage_holin_3_6 PF07332.11 EAX81943.1 - 0.2 11.7 1.1 0.35 10.9 1.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III T5orf172 PF10544.9 EAX81944.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain IQ PF00612.27 EAX81945.1 - 0.0085 15.8 5.6 0.26 11.2 0.6 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif ATP-synt_F PF01990.17 EAX81945.1 - 0.28 11.5 0.7 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit DUF4106 PF13388.6 EAX81946.1 - 3.5e-278 922.5 18.5 6.8e-278 921.6 18.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX81946.1 - 0.069 13.5 0.1 1.9 8.8 0.1 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated DUF4378 PF14309.6 EAX81946.1 - 0.077 13.4 0.4 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) WYL_3 PF18488.1 EAX81946.1 - 0.47 10.8 4.5 18 5.8 0.4 3.2 2 0 0 2 2 2 0 WYL domain DUF2121 PF09894.9 EAX81947.1 - 0.39 10.2 3.8 1.1 8.8 3.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) PTR PF12789.7 EAX81948.1 - 7e-26 90.1 42.6 1.7e-09 37.6 3.6 5.8 5 1 1 6 6 6 5 Phage tail repeat like EMP24_GP25L PF01105.24 EAX81948.1 - 0.029 14.3 9.6 3.4 7.6 1.7 3.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD GUN4_N PF16416.5 EAX81948.1 - 4 7.5 7.6 9.1 6.4 0.3 3.8 3 1 1 4 4 4 0 ARM-like repeat domain, GUN4-N terminal RraB PF06877.11 EAX81948.1 - 6.8 7.5 7.1 54 4.6 2.4 3.5 2 1 0 2 2 2 0 Regulator of ribonuclease activity B RecG_N PF17190.4 EAX81948.1 - 9.6 7.0 16.4 4.2 8.2 0.6 4.4 3 1 1 4 4 4 0 RecG N-terminal helical domain Trypan_PARP PF05887.11 EAX81949.1 - 0.14 12.1 6.3 0.22 11.5 6.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX81950.1 - 0.034 14.6 1.1 0.045 14.2 1.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1746 PF08508.10 EAX81952.1 - 0.01 16.2 1.1 0.32 11.3 0.2 2.3 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1746) Pep1_7 PF17232.2 EAX81952.1 - 0.36 11.3 8.0 31 5.1 0.1 4.0 2 1 2 4 4 4 0 Elicitor peptide 1-7 DUF4107 PF13389.6 EAX81954.1 - 5.2e-72 241.3 4.0 6.8e-72 240.9 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX81954.1 - 0.075 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Peptidase_S64 PF08192.11 EAX81956.1 - 0.0039 15.8 0.0 0.0048 15.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 DUF3781 PF12636.7 EAX81957.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDE_1 PF03184.19 EAX81958.1 - 6.1e-12 45.5 0.2 1.6e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease GPS2_interact PF15784.5 EAX81959.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX81960.1 - 0.077 13.0 10.9 0.12 12.3 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX81961.1 - 5.6e-22 77.7 0.1 1.1e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Latarcin PF10279.9 EAX81961.1 - 5.8 7.4 7.9 3.2 8.2 1.5 2.9 1 1 2 3 3 3 0 Latarcin precursor DUF3839 PF12943.7 EAX81962.1 - 3.9e-153 507.8 11.1 4.8e-153 507.5 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81962.1 - 1.2 9.6 6.6 3.3 8.2 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX81963.1 - 2e-30 104.9 0.1 2.7e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX81963.1 - 0.023 14.7 0.4 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon KilA-N PF04383.13 EAX81964.1 - 1.6e-11 44.0 0.0 3.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX81965.1 - 4.7e-42 142.4 0.6 1.1e-41 141.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain MFS_2 PF13347.6 EAX81966.1 - 5.6e-77 259.1 33.5 6.3e-77 258.9 33.5 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EAX81966.1 - 8.2e-21 74.3 32.2 2.6e-20 72.6 32.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Ndc1_Nup PF09531.10 EAX81966.1 - 0.0017 17.1 1.1 0.0017 17.1 1.1 3.3 1 1 0 3 3 3 2 Nucleoporin protein Ndc1-Nup DUF4231 PF14015.6 EAX81966.1 - 0.046 14.2 0.0 0.046 14.2 0.0 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) DUF3784 PF12650.7 EAX81966.1 - 0.35 11.1 0.0 0.35 11.1 0.0 5.2 3 1 3 6 6 6 0 Domain of unknown function (DUF3784) Myb_DNA-binding PF00249.31 EAX81967.1 - 1.2e-31 108.6 0.5 1.8e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX81967.1 - 1.6e-22 79.5 2.1 1.4e-15 57.3 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX81967.1 - 2.5e-07 30.7 6.1 0.00051 20.0 0.1 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX81967.1 - 8.8e-05 22.3 5.9 0.0019 18.1 0.5 2.8 1 1 1 2 2 2 2 Myb DNA-binding like DUF4424 PF14415.6 EAX81967.1 - 0.00048 19.5 0.4 0.00049 19.5 0.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4424) SANT_DAMP1_like PF16282.5 EAX81967.1 - 0.0024 18.0 1.1 0.065 13.4 0.1 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX81967.1 - 0.003 17.7 0.8 1.6 9.0 0.3 3.0 1 1 1 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 EAX81967.1 - 0.0042 17.2 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF489 PF04356.12 EAX81967.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) RTP801_C PF07809.11 EAX81967.1 - 0.1 12.5 0.5 12 5.8 0.1 2.3 2 0 0 2 2 2 0 RTP801 C-terminal region MULE PF10551.9 EAX81968.1 - 0.019 15.4 1.3 0.1 13.1 0.1 2.6 2 1 1 3 3 3 0 MULE transposase domain DUF2960 PF11173.8 EAX81968.1 - 0.032 14.7 0.3 0.081 13.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) BLOC1_2 PF10046.9 EAX81968.1 - 0.035 14.4 1.0 4.5 7.6 0.1 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3839 PF12943.7 EAX81969.1 - 8.9e-119 395.3 7.3 1e-118 395.1 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX81969.1 - 0.061 12.8 1.0 0.079 12.4 1.0 1.4 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX81969.1 - 0.25 12.0 1.9 0.56 10.9 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DOCK-C2 PF14429.6 EAX81970.1 - 0.0026 17.6 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF4108 PF13390.6 EAX81971.1 - 2e-72 241.8 11.6 2.3e-72 241.6 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Apolipoprotein PF01442.18 EAX81972.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cytadhesin_P30 PF07271.11 EAX81973.1 - 6.1 6.3 16.4 7.7 6.0 16.4 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Alba PF01918.21 EAX81974.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.8 2 1 0 2 2 2 0 Alba PG_binding_2 PF08823.11 EAX81974.1 - 0.014 15.6 0.6 0.024 14.9 0.1 1.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Transpos_assoc PF13963.6 EAX81974.1 - 0.16 12.3 0.4 0.68 10.3 0.1 1.9 1 1 1 2 2 2 0 Transposase-associated domain GPS2_interact PF15784.5 EAX81975.1 - 0.14 12.6 1.9 0.19 12.2 1.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX81976.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX81976.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX81978.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX81978.1 - 0.15 11.0 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Laminin_I PF06008.14 EAX81979.1 - 9e-26 91.1 72.6 0.0014 18.4 4.3 8.2 1 1 7 8 8 8 8 Laminin Domain I KASH_CCD PF14662.6 EAX81979.1 - 9.8e-18 64.7 76.1 1.1e-05 25.4 9.1 6.2 1 1 5 6 6 6 5 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX81979.1 - 6.5e-11 42.0 47.0 0.42 10.0 2.8 10.0 1 1 11 12 12 12 11 Domain of unknown function (DUF3552) ERM PF00769.19 EAX81979.1 - 8.5e-11 42.1 46.9 0.042 13.7 6.1 6.0 1 1 4 5 5 5 5 Ezrin/radixin/moesin family Spc7 PF08317.11 EAX81979.1 - 8.9e-07 28.1 73.8 0.053 12.4 8.2 7.3 1 1 7 8 8 8 6 Spc7 kinetochore protein BRE1 PF08647.11 EAX81979.1 - 7.4e-06 26.0 67.3 0.69 10.0 6.3 8.6 1 1 7 9 9 9 9 BRE1 E3 ubiquitin ligase ZapB PF06005.12 EAX81979.1 - 1.3e-05 25.6 43.5 1.9 9.0 0.9 10.4 1 1 11 12 12 12 1 Cell division protein ZapB DUF4200 PF13863.6 EAX81979.1 - 4.5e-05 23.8 3.1 30 5.0 0.1 6.1 1 1 6 8 8 8 0 Domain of unknown function (DUF4200) JIP_LZII PF16471.5 EAX81979.1 - 6.5e-05 23.0 37.1 19 5.5 0.3 14.2 1 1 17 19 19 19 0 JNK-interacting protein leucine zipper II YabA PF06156.13 EAX81979.1 - 6.5e-05 23.5 29.8 1.8e+04 -19.2 29.8 9.0 1 1 0 1 1 0 0 Initiation control protein YabA Sec34 PF04136.15 EAX81979.1 - 0.00011 22.2 110.0 0.91 9.4 2.7 11.6 1 1 14 15 15 15 5 Sec34-like family GCN5L1 PF06320.13 EAX81979.1 - 0.00011 22.3 41.2 6.3 7.0 0.4 10.1 1 1 12 13 13 13 0 GCN5-like protein 1 (GCN5L1) Laminin_II PF06009.12 EAX81979.1 - 0.00019 21.4 75.1 0.68 9.9 2.5 8.2 1 1 7 8 8 8 6 Laminin Domain II DUF1664 PF07889.12 EAX81979.1 - 0.00031 20.8 47.3 1.2 9.2 1.9 7.9 1 1 7 8 8 8 3 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EAX81979.1 - 0.0032 17.7 60.9 3.9 7.8 0.3 11.3 1 1 9 10 10 10 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 EAX81979.1 - 0.007 16.9 82.4 1.1 9.8 4.4 7.4 1 1 6 7 7 7 2 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EAX81979.1 - 0.012 15.6 25.5 41 4.1 0.1 8.5 1 1 6 7 7 7 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 EAX81979.1 - 0.012 15.6 58.5 0.95 9.5 5.1 6.7 1 1 6 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EAX81979.1 - 0.013 15.5 116.8 0.07 13.2 20.7 7.1 1 1 7 8 8 8 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EAX81979.1 - 0.019 14.3 116.9 0.3 10.4 9.7 7.7 1 1 9 10 10 10 0 Protein of unknown function (DUF3450) GPS2_interact PF15784.5 EAX81979.1 - 0.02 15.3 43.7 2.2 8.8 1.9 7.9 2 2 7 9 9 9 0 G-protein pathway suppressor 2-interacting domain UPF0449 PF15136.6 EAX81979.1 - 0.038 14.5 70.5 2 8.9 3.7 10.3 1 1 6 7 7 7 0 Uncharacterised protein family UPF0449 TACC_C PF05010.14 EAX81979.1 - 0.04 13.7 41.9 0.78 9.5 3.2 6.2 1 1 5 6 6 6 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 EAX81979.1 - 0.059 13.6 81.3 4.4 7.5 2.5 8.6 1 1 9 10 10 10 0 JNK_SAPK-associated protein-1 DUF4686 PF15742.5 EAX81979.1 - 0.089 11.9 79.6 1.5 7.9 19.3 5.5 1 1 7 8 8 8 0 Domain of unknown function (DUF4686) COG7 PF10191.9 EAX81979.1 - 0.12 10.6 80.3 0.18 10.0 6.6 8.6 1 1 7 8 8 8 0 Golgi complex component 7 (COG7) Fib_alpha PF08702.10 EAX81979.1 - 0.25 11.5 61.0 0.87 9.8 2.7 7.0 1 1 6 7 7 7 0 Fibrinogen alpha/beta chain family CheZ PF04344.13 EAX81979.1 - 1.6 8.6 59.5 1.1 9.1 0.3 7.0 1 1 7 8 8 8 0 Chemotaxis phosphatase, CheZ DUF4795 PF16043.5 EAX81979.1 - 5.5 6.5 75.1 25 4.4 0.9 8.2 1 1 3 4 4 3 0 Domain of unknown function (DUF4795) Lebercilin PF15619.6 EAX81980.1 - 0.041 13.6 2.8 0.049 13.3 2.8 1.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 EAX81980.1 - 0.059 13.7 1.1 0.089 13.1 1.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pertus-S5-tox PF09276.10 EAX81980.1 - 0.073 13.1 0.2 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 Pertussis toxin S5 subunit DUF1664 PF07889.12 EAX81980.1 - 0.076 13.1 0.2 0.095 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 EAX81980.1 - 0.11 12.7 8.1 0.16 12.1 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor Pox_A32 PF04665.12 EAX81981.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81981.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX81981.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81981.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81981.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX81981.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX81982.1 - 1.8e-31 108.3 0.2 4.6e-31 107.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX81983.1 - 0.06 13.9 0.0 0.091 13.3 0.0 1.4 1 1 0 1 1 1 0 T5orf172 domain DUF3839 PF12943.7 EAX81984.1 - 1.4e-152 506.0 12.1 1.8e-152 505.7 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX81984.1 - 0.27 12.2 1.6 0.55 11.2 0.4 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Glu-tRNAGln PF02686.15 EAX81984.1 - 2 8.8 4.2 1.6 9.1 1.3 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX81984.1 - 2.3 8.7 6.6 1.8 9.1 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX81985.1 - 9.4e-157 519.7 13.5 1.2e-156 519.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX81985.1 - 1.1 9.8 6.2 4.8 7.7 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX81987.1 - 5.9e-06 25.9 2.0 8.8e-06 25.3 2.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX81987.1 - 0.0038 16.9 0.2 0.0055 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX81987.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX81987.1 - 0.043 13.3 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX81987.1 - 0.044 13.5 0.3 0.19 11.4 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX81987.1 - 0.072 12.8 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX81987.1 - 0.14 12.1 2.4 1.1 9.3 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) TrmK PF04816.12 EAX81987.1 - 0.18 11.3 3.0 0.29 10.7 3.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DUF2666 PF10869.8 EAX81987.1 - 0.54 10.5 8.8 4.6 7.5 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_D5 PF03288.16 EAX81989.1 - 0.00012 22.5 1.8 0.00059 20.3 1.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX81989.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF4107 PF13389.6 EAX81990.1 - 4.6e-73 244.7 3.6 6e-73 244.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Gly-zipper_Omp PF13488.6 EAX81992.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX81992.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX81992.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX81992.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX81992.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Amidase02_C PF12123.8 EAX81995.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase LRR_5 PF13306.6 EAX81996.1 - 2e-35 121.5 7.3 3e-35 121.0 7.3 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX81996.1 - 0.00059 19.5 0.0 0.48 10.2 0.2 3.1 1 1 3 4 4 4 3 Leucine rich repeat DUF745 PF05335.13 EAX81998.1 - 0.0021 17.8 16.1 0.0066 16.2 14.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF745) SesA PF17107.5 EAX81998.1 - 0.0099 16.1 5.8 0.0099 16.1 5.8 1.9 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Tropomyosin_1 PF12718.7 EAX81998.1 - 0.01 16.0 26.2 0.029 14.5 8.5 2.9 1 1 2 3 3 3 0 Tropomyosin like SKA1 PF07160.12 EAX81998.1 - 0.076 12.9 16.2 0.18 11.6 14.7 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 EAX81998.1 - 0.098 12.8 26.1 0.17 12.0 8.6 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Cast PF10174.9 EAX81998.1 - 0.13 10.4 24.4 0.088 11.0 22.8 1.4 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SlyX PF04102.12 EAX81998.1 - 0.15 12.7 19.1 0.92 10.2 1.2 5.0 1 1 4 5 5 5 0 SlyX Golgin_A5 PF09787.9 EAX81998.1 - 0.21 11.0 29.4 0.075 12.5 25.2 2.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Myosin_tail_1 PF01576.19 EAX81998.1 - 0.22 9.3 26.5 0.27 9.0 26.5 1.0 1 0 0 1 1 1 0 Myosin tail Tropomyosin PF00261.20 EAX81998.1 - 0.29 10.5 25.0 0.72 9.2 3.6 3.3 1 1 1 3 3 3 0 Tropomyosin Lebercilin PF15619.6 EAX81998.1 - 0.4 10.3 27.5 15 5.1 27.5 2.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CTU2 PF10288.9 EAX81998.1 - 0.9 9.8 0.0 0.9 9.8 0.0 2.8 1 1 1 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PCRF PF03462.18 EAX81998.1 - 1.2 9.0 14.7 0.57 10.0 9.5 2.1 1 1 1 2 2 2 0 PCRF domain Csm1_N PF18504.1 EAX81998.1 - 1.7 9.1 24.2 1.4 9.3 1.6 4.7 4 1 1 5 5 5 0 Csm1 N-terminal domain OmpH PF03938.14 EAX81998.1 - 1.7 9.0 19.1 2.3 8.5 13.3 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 EAX81998.1 - 1.7 8.7 28.3 4.9 7.2 15.1 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 EAX81998.1 - 2 8.0 21.0 12 5.6 9.0 3.1 1 1 2 3 3 3 0 GrpE PKcGMP_CC PF16808.5 EAX81998.1 - 2.2 8.2 11.2 0.45 10.4 0.3 3.8 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 EAX81998.1 - 3.1 7.9 28.6 4.1 7.5 5.1 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 EAX81998.1 - 3.7 7.6 9.9 8.3 6.5 2.0 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EAX81998.1 - 4 6.2 27.9 0.23 10.3 10.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Bap31_Bap29_C PF18035.1 EAX81998.1 - 6.4 6.9 10.9 0.6 10.1 0.7 3.5 2 2 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF724 PF05266.14 EAX81998.1 - 7.8 6.3 23.8 6.1 6.6 11.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_HK97_TLTM PF06120.11 EAX81998.1 - 8.7 5.4 14.4 68 2.5 14.4 2.0 1 1 0 1 1 1 0 Tail length tape measure protein TMF_TATA_bd PF12325.8 EAX81998.1 - 10 6.4 23.8 0.59 10.4 13.0 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3213 PF11491.8 EAX81999.1 - 0.016 15.4 0.1 0.071 13.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) MMS19_N PF14500.6 EAX81999.1 - 0.04 13.5 4.5 0.83 9.2 0.0 3.8 3 1 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II RasGEF_N PF00618.20 EAX81999.1 - 1.3 9.3 17.0 12 6.1 6.6 4.8 3 2 1 4 4 4 0 RasGEF N-terminal motif KilA-N PF04383.13 EAX82000.1 - 3.8e-41 139.4 1.5 6e-41 138.8 0.3 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82000.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KilA-N PF04383.13 EAX82002.1 - 1.5e-36 124.6 0.2 2.5e-36 123.9 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX82003.1 - 4.1e-156 517.6 10.9 5.1e-156 517.3 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82003.1 - 0.19 12.2 3.7 10 6.6 0.1 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX82007.1 - 1.1e-72 243.4 4.2 1.4e-72 243.2 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX82007.1 - 0.21 10.0 0.9 0.3 9.4 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase Ank_4 PF13637.6 EAX82008.1 - 1.3e-17 63.9 0.0 2.2e-10 40.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX82008.1 - 1.8e-14 54.1 0.2 2.5e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX82008.1 - 1.2e-11 43.7 0.1 0.0037 17.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX82008.1 - 1.6e-08 34.6 0.0 0.0084 16.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX82008.1 - 7.6e-08 32.5 0.0 2e-05 24.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pox_A32 PF04665.12 EAX82009.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX82009.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX82009.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX82009.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.8 EAX82010.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX82011.1 - 2.9e-34 118.6 1.9 3.3e-34 118.4 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX82014.1 - 1.6e-24 85.9 1.0 2.8e-24 85.1 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX82015.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82015.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82015.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82015.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82015.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82015.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82015.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82015.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82015.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82015.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82015.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82015.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX82017.1 - 9.6e-138 457.4 13.9 2.9e-137 455.8 13.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82017.1 - 5.6 7.5 7.3 5.1 7.6 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase WRKY PF03106.15 EAX82020.1 - 0.011 16.0 3.6 0.028 14.7 0.9 2.7 1 1 1 2 2 2 0 WRKY DNA -binding domain DUF4107 PF13389.6 EAX82021.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MKLP1_Arf_bdg PF16540.5 EAX82022.1 - 2.5 8.2 7.3 3.1 7.9 7.3 1.2 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Glutaminase PF04960.15 EAX82022.1 - 3.2 6.8 8.0 2.3 7.3 1.1 2.0 1 1 1 2 2 2 0 Glutaminase GPS2_interact PF15784.5 EAX82024.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82024.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX82025.1 - 0.34 10.9 12.5 0.39 10.7 12.5 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2897 PF11446.8 EAX82026.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX82027.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX82028.1 - 1.4e-05 25.5 0.4 2.1e-05 24.9 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82028.1 - 0.015 15.9 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82028.1 - 0.038 14.0 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain T5orf172 PF10544.9 EAX82029.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX82030.1 - 5.9e-154 510.5 13.4 7.5e-154 510.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82030.1 - 0.27 11.1 1.9 0.7 9.7 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF5398 PF17376.2 EAX82030.1 - 0.33 11.6 3.0 1.2 9.8 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX82030.1 - 0.87 10.1 6.2 5.2 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82031.1 - 0.00095 19.7 0.3 0.0021 18.6 0.3 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX82031.1 - 0.16 11.5 0.2 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Legume lectin domain PSP PF04046.16 EAX82033.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX82034.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX82035.1 - 0.074 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX82036.1 - 3e-51 171.3 32.7 1e-32 112.0 14.6 4.5 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX82036.1 - 0.086 12.6 0.1 0.086 12.6 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX82037.1 - 2.2e-07 30.6 2.6 3.2e-07 30.1 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82037.1 - 0.0045 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82037.1 - 0.056 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82037.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82037.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82037.1 - 0.51 10.6 8.3 5.7 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX82038.1 - 4.1e-157 520.9 14.6 5e-157 520.6 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX82038.1 - 0.097 13.1 0.4 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX82038.1 - 0.34 11.4 7.8 2.3 8.8 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX82039.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX82039.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82039.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ank_4 PF13637.6 EAX82040.1 - 3.3e-45 151.9 14.9 2.4e-11 43.9 0.5 6.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX82040.1 - 2.6e-43 146.5 6.6 1.8e-14 54.1 0.7 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX82040.1 - 1.2e-37 126.7 7.2 3.6e-09 36.6 0.5 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX82040.1 - 1.5e-32 111.2 2.5 1.8e-09 37.6 0.6 4.7 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82040.1 - 3.4e-32 106.9 14.7 1.4e-05 25.1 0.2 8.5 8 1 0 8 8 8 6 Ankyrin repeat DUF3718 PF12514.8 EAX82040.1 - 0.15 12.3 4.7 2.6 8.2 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) s48_45 PF07422.13 EAX82040.1 - 0.19 12.3 2.3 0.49 11.0 2.3 2.1 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain KilA-N PF04383.13 EAX82042.1 - 7.6e-44 148.1 0.3 2e-43 146.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82042.1 - 0.0059 17.2 0.1 0.018 15.7 0.0 1.9 3 0 0 3 3 3 1 Parathyroid hormone family KilA-N PF04383.13 EAX82044.1 - 1.5e-06 28.1 1.0 1.9e-06 27.7 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX82045.1 - 3.8e-157 521.0 12.4 4.7e-157 520.6 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82045.1 - 0.22 12.0 5.4 0.57 10.7 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82046.1 - 0.00011 22.7 0.6 0.0003 21.3 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX82046.1 - 0.017 14.6 0.3 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF5446 PF17522.2 EAX82047.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX82048.1 - 1e-40 139.7 4.5 1.4e-40 139.3 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82048.1 - 0.041 14.4 0.6 0.048 14.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX82048.1 - 0.32 11.5 2.0 0.66 10.5 1.2 2.1 2 1 0 2 2 2 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX82048.1 - 0.39 11.1 2.5 1.2 9.5 1.3 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DDR PF08841.10 EAX82050.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX82050.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CGI-121 PF08617.10 EAX82053.1 - 0.087 12.9 0.1 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Kinase binding protein CGI-121 rve PF00665.26 EAX82054.1 - 0.0041 17.3 0.1 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF3746 PF12562.8 EAX82054.1 - 0.59 10.1 4.9 0.4 10.6 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF3839 PF12943.7 EAX82055.1 - 1.4e-16 60.7 1.5 2.1e-16 60.1 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX82055.1 - 0.025 15.0 1.3 0.088 13.3 0.4 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF1811 PF08838.10 EAX82055.1 - 0.1 12.8 0.7 0.34 11.2 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1811) FliD_N PF02465.18 EAX82057.1 - 0.43 11.3 3.9 0.71 10.6 3.9 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX82057.1 - 3.5 6.3 4.6 4.6 5.9 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FBA PF04300.13 EAX82060.1 - 0.15 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 F-box associated region DUF3839 PF12943.7 EAX82061.1 - 2.2e-156 518.5 14.5 2.8e-156 518.1 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82061.1 - 0.1 12.9 0.3 2.1 8.7 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX82061.1 - 0.24 11.2 1.5 0.78 9.6 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82061.1 - 0.82 10.2 7.9 1.9 9.0 1.1 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UQ_con PF00179.26 EAX82062.1 - 1.3e-37 128.5 1.4 1.5e-37 128.3 1.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EAX82062.1 - 0.0011 18.8 0.6 0.0019 18.0 0.4 1.5 1 1 0 1 1 1 1 UEV domain DUF4455 PF14643.6 EAX82063.1 - 0.0019 16.9 6.5 0.004 15.9 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4455) WXG100 PF06013.12 EAX82063.1 - 0.085 13.1 0.3 0.42 10.9 0.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG SPACA7 PF15307.6 EAX82063.1 - 0.22 11.8 5.0 0.2 11.9 2.3 2.2 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 DUF4107 PF13389.6 EAX82064.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) BUD22 PF09073.10 EAX82066.1 - 3 7.1 10.8 3.4 6.9 10.8 1.1 1 0 0 1 1 1 0 BUD22 120_Rick_ant PF12574.8 EAX82067.1 - 0.0028 16.9 0.4 0.0033 16.7 0.4 1.1 1 0 0 1 1 1 1 120 KDa Rickettsia surface antigen Fibroin_P25 PF07294.11 EAX82067.1 - 0.072 13.1 0.1 0.083 12.9 0.1 1.1 1 0 0 1 1 1 0 Fibroin P25 Beta_helix PF13229.6 EAX82068.1 - 0.048 13.5 0.7 0.059 13.2 0.7 1.1 1 0 0 1 1 1 0 Right handed beta helix region DUF1251 PF06856.11 EAX82068.1 - 0.05 13.3 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) Spo12 PF05032.12 EAX82069.1 - 0.43 10.5 7.7 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX82070.1 - 5e-14 52.1 0.1 9.6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX82070.1 - 0.038 13.4 0.4 0.075 12.4 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX82071.1 - 3e-156 518.0 10.2 3.7e-156 517.7 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82071.1 - 0.091 13.2 4.6 0.77 10.3 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82071.1 - 0.39 11.0 2.9 14 6.1 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX82071.1 - 0.74 10.4 3.9 0.5 10.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_22 PF13401.6 EAX82072.1 - 6.3e-05 23.3 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82072.1 - 8.1e-05 22.7 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82072.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82072.1 - 0.00089 19.1 0.9 0.0026 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82072.1 - 0.0026 17.5 0.2 0.27 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX82072.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82072.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82072.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX82072.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX82072.1 - 0.25 11.6 4.4 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX82074.1 - 2.7e-59 199.2 6.4 3e-59 199.1 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX82075.1 - 7.3e-05 23.2 2.6 0.0004 20.8 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX82075.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) DUF3839 PF12943.7 EAX82076.1 - 3.6e-157 521.1 11.3 4.4e-157 520.7 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82076.1 - 0.26 11.8 4.9 9.3 6.8 0.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82076.1 - 5 7.5 7.3 12 6.3 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal DUF3839 PF12943.7 EAX82077.1 - 4.4e-78 262.1 10.1 5.7e-78 261.7 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX82078.1 - 1.5e-40 139.2 1.2 1.7e-40 139.0 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX82078.1 - 0.079 13.4 0.1 0.088 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) DUF5398 PF17376.2 EAX82078.1 - 0.12 13.0 0.7 0.56 10.9 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX82079.1 - 5.9e-41 138.8 2.2 5.9e-41 138.8 2.2 2.3 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82079.1 - 0.0047 17.5 0.4 0.021 15.4 0.0 2.2 2 0 0 2 2 2 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX82079.1 - 0.13 12.5 7.7 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF3839 PF12943.7 EAX82080.1 - 2.3e-79 266.3 9.9 3e-79 265.9 9.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82080.1 - 0.042 14.3 0.3 0.053 14.0 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX82080.1 - 0.047 14.2 0.7 0.081 13.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX82080.1 - 0.13 11.7 0.2 0.83 9.1 0.0 2.1 2 1 1 3 3 3 0 SLOG cluster2 DUF3839 PF12943.7 EAX82081.1 - 1.1e-56 192.0 4.2 1.2e-56 191.9 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82081.1 - 0.025 14.1 0.2 0.028 13.9 0.2 1.0 1 0 0 1 1 1 0 Z1 domain Trypan_PARP PF05887.11 EAX82082.1 - 0.11 12.4 12.1 0.12 12.3 12.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82082.1 - 1 9.8 5.7 1.2 9.6 5.7 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX82083.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82083.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 EAX82084.1 - 4.2e-60 200.3 10.6 2.8e-21 75.9 0.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX82084.1 - 8.4e-32 108.2 0.0 2.7e-05 24.4 0.0 5.8 6 0 0 6 6 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX82084.1 - 9.7e-32 108.6 1.0 1.2e-08 35.1 0.0 5.4 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX82084.1 - 9.9e-31 105.7 0.0 6.4e-11 42.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82084.1 - 3.3e-24 82.3 0.0 0.0044 17.4 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat DUF1664 PF07889.12 EAX82084.1 - 0.043 13.9 5.3 0.083 12.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC74_C PF14917.6 EAX82084.1 - 0.12 12.9 2.2 0.22 12.0 2.2 1.5 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal DivIC PF04977.15 EAX82084.1 - 0.13 12.1 4.0 0.44 10.3 4.0 2.0 1 0 0 1 1 1 0 Septum formation initiator DUF1897 PF09005.10 EAX82084.1 - 0.15 11.6 0.0 1.4e+02 2.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) DAP_B PF07930.12 EAX82084.1 - 0.15 12.0 0.3 0.33 10.9 0.3 1.6 1 0 0 1 1 1 0 D-aminopeptidase, domain B DUF2115 PF09888.9 EAX82084.1 - 0.17 12.4 9.3 0.36 11.3 5.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Fib_alpha PF08702.10 EAX82084.1 - 0.31 11.2 9.8 0.26 11.5 6.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nas2_N PF18265.1 EAX82084.1 - 0.34 10.9 3.2 0.53 10.2 1.9 2.1 1 1 0 1 1 1 0 Nas2 N_terminal domain SlyX PF04102.12 EAX82084.1 - 1.5 9.5 7.0 2.1 9.0 4.8 2.2 2 0 0 2 2 2 0 SlyX DUF3839 PF12943.7 EAX82085.1 - 2.4e-155 515.0 11.8 3e-155 514.7 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82085.1 - 0.81 10.0 3.0 3.7 7.9 0.0 3.0 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82085.1 - 1.3 9.5 4.4 4.9 7.7 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX82086.1 - 0.036 14.5 0.3 0.046 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX82087.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX82087.1 - 0.052 13.5 0.6 0.077 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Clathrin PF00637.20 EAX82089.1 - 7.1e-54 181.6 6.8 2.1e-29 102.3 1.9 2.2 2 0 0 2 2 2 2 Region in Clathrin and VPS DUF2383 PF09537.10 EAX82089.1 - 0.028 14.8 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF4795 PF16043.5 EAX82090.1 - 0.0024 17.5 7.5 0.33 10.5 1.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAX82090.1 - 0.39 11.0 2.2 4.2 7.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Phage_fiber PF03335.13 EAX82090.1 - 1.8 9.0 9.8 0.44 10.8 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat GPS2_interact PF15784.5 EAX82093.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82093.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX82094.1 - 0.025 14.6 8.5 0.033 14.2 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82094.1 - 1.6 9.2 5.6 2 8.9 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX82095.1 - 4.1e-42 142.5 0.1 1.1e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82095.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family GGDEF PF00990.21 EAX82096.1 - 0.072 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF3464 PF11947.8 EAX82096.1 - 0.68 9.7 2.7 0.6 9.9 2.0 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX82097.1 - 1.1e-58 197.2 8.8 1.3e-58 197.0 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) zf-B_box PF00643.24 EAX82099.1 - 0.17 12.1 0.4 0.28 11.4 0.4 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF4107 PF13389.6 EAX82100.1 - 2.9e-72 242.1 4.0 3.5e-72 241.9 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX82102.1 - 1.5e-147 489.5 10.5 2.3e-147 488.9 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX82102.1 - 1e-05 26.0 0.0 8.4e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX82102.1 - 0.017 14.6 0.2 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 Legume lectin domain Fez1 PF06818.15 EAX82102.1 - 0.036 14.5 0.7 0.18 12.2 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82102.1 - 0.54 10.7 2.9 3 8.4 0.1 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82103.1 - 1.8e-06 28.4 0.3 3.8e-06 27.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82104.1 - 2.7e-34 117.4 0.4 6.1e-34 116.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain RPAP3_C PF13877.6 EAX82104.1 - 0.014 15.9 0.8 0.067 13.7 0.1 2.2 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 PapD_N PF00345.20 EAX82106.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX82107.1 - 0.016 15.6 0.4 0.022 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX82108.1 - 0.015 15.3 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX82109.1 - 1.1e-143 476.9 9.8 1.3e-143 476.6 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LRR_5 PF13306.6 EAX82110.1 - 3.6e-52 175.7 24.3 8e-17 61.4 1.4 4.8 2 1 4 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX82110.1 - 2.2e-06 27.3 0.0 5.8 6.8 0.0 5.9 4 2 2 6 6 6 2 Leucine rich repeat Pentapeptide_4 PF13599.6 EAX82110.1 - 0.016 15.3 0.1 0.61 10.3 0.0 3.3 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EAX82110.1 - 0.017 15.3 0.9 0.36 11.0 0.0 3.3 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Chordopox_E11 PF06138.12 EAX82110.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus E11 protein DUF3839 PF12943.7 EAX82111.1 - 2.6e-103 344.7 5.2 2.9e-103 344.5 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82111.1 - 0.071 12.6 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Z1 domain TMP PF05017.14 EAX82112.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX82113.1 - 0.082 13.4 0.2 0.18 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF257 PF03192.13 EAX82114.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX82114.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p KilA-N PF04383.13 EAX82117.1 - 1.1e-33 115.4 0.1 1.3e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain DUF4108 PF13390.6 EAX82118.1 - 3.5e-78 260.4 12.7 4.1e-78 260.2 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX82119.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX82119.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82119.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4107 PF13389.6 EAX82122.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX82123.1 - 2.9e-31 108.8 0.3 3.5e-31 108.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4309 PF14172.6 EAX82123.1 - 0.09 12.8 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DUF3839 PF12943.7 EAX82124.1 - 1.8e-157 522.1 13.4 2.2e-157 521.7 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX82124.1 - 0.037 14.3 0.7 0.093 13.0 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX82124.1 - 0.057 13.9 1.1 0.46 10.9 0.1 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82124.1 - 0.68 10.4 7.1 1.9 9.0 0.8 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX82126.1 - 1.1e-06 28.3 3.5 1.1e-06 28.3 3.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82126.1 - 3.7e-05 24.0 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82126.1 - 5.3e-05 23.0 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82126.1 - 0.00012 22.1 3.3 0.00028 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82126.1 - 0.00043 20.1 0.1 0.00081 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82126.1 - 0.00088 19.1 0.4 0.0015 18.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82126.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82126.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82126.1 - 0.073 12.6 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX82126.1 - 0.09 12.5 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX82126.1 - 0.092 13.2 0.1 0.77 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82126.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82126.1 - 0.44 10.8 3.9 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82127.1 - 1.9e-42 143.6 0.3 4.3e-42 142.5 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82127.1 - 0.0054 17.3 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family KilA-N PF04383.13 EAX82128.1 - 2.4e-44 149.7 1.2 3.3e-44 149.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82128.1 - 0.0034 18.0 0.4 0.012 16.2 0.0 2.1 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX82129.1 - 3.5e-07 29.9 2.2 3.5e-07 29.9 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82129.1 - 3e-05 24.3 0.2 0.00023 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82129.1 - 5.6e-05 22.9 0.3 0.49 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82129.1 - 0.00012 22.1 2.9 0.00032 20.7 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82129.1 - 0.00062 19.6 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX82129.1 - 0.00083 19.1 0.6 0.0052 16.4 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX82129.1 - 0.0014 18.5 0.5 0.0027 17.5 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82129.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82129.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82129.1 - 0.089 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82129.1 - 0.092 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82129.1 - 0.52 10.6 4.5 7.8 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX82130.1 - 4.2e-156 517.5 15.1 5.8e-156 517.1 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82130.1 - 0.0056 16.5 0.8 0.012 15.4 0.8 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase DUF3549 PF12069.8 EAX82130.1 - 0.0095 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) DUF29 PF01724.16 EAX82130.1 - 0.043 14.1 1.2 0.14 12.4 0.2 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF29 Z1 PF10593.9 EAX82130.1 - 0.17 11.4 5.5 0.11 11.9 1.3 2.4 1 1 1 2 2 2 0 Z1 domain MitMem_reg PF13012.6 EAX82130.1 - 0.19 12.2 1.0 0.71 10.3 0.1 2.2 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX82130.1 - 0.31 11.5 3.3 1.4 9.4 0.3 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX82130.1 - 0.58 10.5 4.3 1.9 8.8 0.1 3.2 3 2 0 3 3 3 0 PRD domain Clathrin PF00637.20 EAX82133.1 - 7.7e-120 395.4 22.8 4.3e-29 101.2 0.1 6.2 5 1 1 6 6 6 6 Region in Clathrin and VPS TPR_2 PF07719.17 EAX82133.1 - 0.00082 19.3 1.5 2.1 8.7 0.1 3.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX82133.1 - 0.0047 16.7 1.6 5.9 6.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX82133.1 - 0.0097 16.7 7.5 3.2 8.8 0.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EAX82133.1 - 0.019 14.0 3.8 1 8.3 0.6 2.6 2 0 0 2 2 2 0 Coatomer WD associated region BCIP PF13862.6 EAX82133.1 - 0.026 14.3 0.4 0.09 12.5 0.1 2.1 2 0 0 2 2 2 0 p21-C-terminal region-binding protein DUF1400 PF07176.11 EAX82133.1 - 0.054 13.8 2.4 22 5.3 0.0 4.1 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_7 PF13176.6 EAX82133.1 - 0.067 13.3 1.0 1.1 9.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 EAX82133.1 - 0.076 13.3 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_6 PF13921.6 EAX82133.1 - 0.099 12.9 0.2 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain TPR_8 PF13181.6 EAX82133.1 - 4.7 7.7 6.9 1.6 9.1 0.2 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat T5orf172 PF10544.9 EAX82134.1 - 2.2e-06 28.2 0.1 4.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82135.1 - 1.5e-38 131.1 0.8 3.5e-38 129.9 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX82137.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX82137.1 - 0.21 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX82139.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX82142.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82142.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82142.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82142.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) LRR_5 PF13306.6 EAX82143.1 - 9.1e-29 100.0 7.9 8.5e-21 74.2 0.4 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX82143.1 - 0.00097 18.9 0.1 1.1 9.1 0.0 2.9 2 1 1 3 3 3 2 Leucine rich repeat Frag1 PF10277.9 EAX82144.1 - 2.1e-13 50.3 24.8 2.4e-13 50.2 24.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF5325 PF17259.2 EAX82144.1 - 6.6 6.7 8.9 2.2 8.2 0.8 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5325) Bromodomain PF00439.25 EAX82145.1 - 0.032 14.3 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Bromodomain HSBP1 PF06825.12 EAX82145.1 - 0.043 13.7 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF1660 PF07874.11 EAX82145.1 - 0.096 13.2 0.2 0.26 11.8 0.0 1.8 2 0 0 2 2 2 0 Prophage protein (DUF1660) Oxidored_FMN PF00724.20 EAX82146.1 - 8.7e-58 196.2 0.0 1.1e-57 195.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 EAX82146.1 - 1.6e-05 24.5 0.0 4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF3839 PF12943.7 EAX82147.1 - 6.1e-117 389.3 7.5 7.1e-117 389.1 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82147.1 - 0.01 15.7 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX82148.1 - 6.3e-07 29.9 0.5 3.4e-06 27.5 0.2 2.2 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX82148.1 - 0.0077 15.8 0.6 0.084 12.4 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX82149.1 - 1.6e-31 108.5 0.4 4.4e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF4107 PF13389.6 EAX82153.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX82154.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Trypan_PARP PF05887.11 EAX82156.1 - 0.093 12.7 6.6 0.14 12.1 6.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82156.1 - 2.5 8.5 5.1 3.6 8.0 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX82157.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82157.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX82159.1 - 6.8e-34 116.1 0.7 1.3e-33 115.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX82159.1 - 0.15 12.8 1.7 11 6.8 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3839 PF12943.7 EAX82160.1 - 3.3e-155 514.6 11.9 4.1e-155 514.3 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82160.1 - 0.55 10.6 3.6 1.6 9.1 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82160.1 - 0.82 10.2 6.1 5 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82160.1 - 3.7 7.9 7.4 12 6.3 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal DDR PF08841.10 EAX82162.1 - 0.049 12.6 0.1 0.05 12.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX82162.1 - 0.13 12.8 1.4 0.18 12.2 1.4 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Zn_peptidase PF04228.13 EAX82163.1 - 0.16 11.4 0.8 1.7 8.0 0.1 2.0 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase KilA-N PF04383.13 EAX82169.1 - 3.7e-17 62.2 0.3 7.2e-17 61.3 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX82170.1 - 4.7e-154 510.8 14.7 6e-154 510.5 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82170.1 - 0.022 15.0 0.7 0.38 11.0 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82170.1 - 0.43 11.1 6.9 1.8 9.1 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5446 PF17522.2 EAX82171.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) HTH_AraC PF00165.23 EAX82172.1 - 0.081 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family PMBR PF09373.10 EAX82172.1 - 0.1 12.8 0.5 24 5.3 0.0 3.6 4 0 0 4 4 4 0 Pseudomurein-binding repeat Gly-zipper_Omp PF13488.6 EAX82174.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX82174.1 - 0.64 10.3 5.9 1.1 9.6 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Cytadhesin_P30 PF07271.11 EAX82175.1 - 5.1 6.6 18.1 6.3 6.3 18.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 NMT PF01233.19 EAX82176.1 - 0.084 12.7 0.3 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain KilA-N PF04383.13 EAX82177.1 - 1.3e-41 140.9 1.5 1.6e-41 140.7 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX82177.1 - 0.13 12.3 6.3 0.25 11.3 6.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Pox_A32 PF04665.12 EAX82178.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82178.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82178.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82178.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82178.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX82178.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82178.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX82179.1 - 4.1e-33 113.6 0.5 9.6e-33 112.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82179.1 - 0.036 14.7 0.0 0.096 13.3 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family Ycf34 PF10718.9 EAX82179.1 - 0.062 14.0 1.6 11 6.8 0.3 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 T5orf172 PF10544.9 EAX82180.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX82181.1 - 1.5e-154 512.5 11.9 1.9e-154 512.1 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82181.1 - 5 7.6 7.5 1.9 9.0 0.7 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82183.1 - 2.8e-06 27.8 0.2 6.4e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82183.1 - 0.0021 17.9 0.1 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX82184.1 - 3e-40 136.6 0.3 3e-40 136.6 0.3 2.0 2 1 0 2 2 2 1 KilA-N domain Peptidase_S10 PF00450.22 EAX82184.1 - 0.47 9.8 3.2 0.16 11.3 0.6 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase Pox_A32 PF04665.12 EAX82186.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82186.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82186.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82186.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82186.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX82186.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82186.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX82189.1 - 3.6e-07 29.9 2.7 3.6e-07 29.9 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82189.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82189.1 - 0.00016 21.7 3.0 0.00037 20.5 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX82189.1 - 0.00023 20.9 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX82189.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82189.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82189.1 - 0.0013 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82189.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82189.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82189.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82189.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2897 PF11446.8 EAX82190.1 - 1.9 8.4 3.7 3.6 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) JMY PF15871.5 EAX82192.1 - 0.0032 16.9 0.4 0.0052 16.1 0.4 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX82192.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF5065 PF16723.5 EAX82192.1 - 0.71 9.9 3.4 0.56 10.3 0.7 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5065) DUF3839 PF12943.7 EAX82193.1 - 2.2e-147 489.0 12.3 2.8e-147 488.7 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82193.1 - 0.012 16.0 0.5 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX82193.1 - 0.11 12.4 1.7 0.39 10.6 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase CENP-F_leu_zip PF10473.9 EAX82193.1 - 0.13 12.2 2.4 5.7 7.0 1.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 EAX82193.1 - 0.58 10.6 5.0 2.4 8.7 1.1 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 EAX82194.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX82194.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82194.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4795 PF16043.5 EAX82195.1 - 0.014 15.0 5.0 0.86 9.2 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ESAG1 PF03238.13 EAX82195.1 - 0.033 13.6 2.9 0.57 9.6 0.2 3.2 2 1 2 4 4 4 0 ESAG protein GST_C PF00043.25 EAX82195.1 - 0.14 12.4 0.8 3.4 8.0 0.5 3.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain PTR PF12789.7 EAX82196.1 - 1.8e-17 63.1 24.5 5.9e-08 32.6 5.3 5.7 5 0 0 5 5 5 4 Phage tail repeat like LIFR_D2 PF17971.1 EAX82196.1 - 0.0086 16.3 0.0 24 5.2 0.0 3.3 1 1 1 3 3 3 1 Leukemia inhibitory factor receptor D2 domain TT_ORF2a PF08197.11 EAX82196.1 - 0.035 14.1 0.0 73 3.5 0.0 3.3 3 0 0 3 3 3 0 pORF2a truncated protein Ribosomal_S4e PF00900.20 EAX82196.1 - 0.15 12.0 0.9 1.4e+02 2.5 0.0 3.7 3 0 0 3 3 3 0 Ribosomal family S4e HiaBD2 PF15403.6 EAX82196.1 - 8.5 6.9 7.8 1.4e+02 3.0 0.2 3.8 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF3839 PF12943.7 EAX82197.1 - 5.3e-156 517.2 12.1 6.6e-156 516.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82197.1 - 0.09 13.2 2.5 0.22 12.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82197.1 - 0.45 11.0 6.6 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82197.1 - 0.83 10.2 6.5 0.25 11.9 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Trypan_PARP PF05887.11 EAX82198.1 - 0.047 13.7 13.1 0.076 13.0 13.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX82198.1 - 3.6 5.1 21.6 5.9 4.4 21.6 1.3 1 1 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX82198.1 - 5.1 7.6 6.2 7.4 7.0 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX82199.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82199.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX82201.1 - 3.8e-59 198.7 9.8 4.2e-59 198.6 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX82201.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Arch_flagellin PF01917.16 EAX82203.1 - 0.17 12.0 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin T5orf172 PF10544.9 EAX82205.1 - 6.3e-06 26.7 0.3 7.6e-05 23.2 0.2 2.4 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX82205.1 - 0.0061 16.1 0.3 0.7 9.4 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX82205.1 - 0.049 13.5 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain DUF3148 PF11347.8 EAX82205.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) DUF3839 PF12943.7 EAX82206.1 - 7.7e-153 506.9 13.1 9e-153 506.6 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX82206.1 - 0.17 12.2 2.7 0.32 11.3 1.0 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit AAA_22 PF13401.6 EAX82207.1 - 6.3e-05 23.3 0.1 0.00035 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82207.1 - 7.5e-05 22.8 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82207.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82207.1 - 0.0013 18.6 1.4 0.0043 16.9 1.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82207.1 - 0.0021 17.8 0.3 0.22 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX82207.1 - 0.0078 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82207.1 - 0.049 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX82207.1 - 0.075 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX82207.1 - 0.095 13.1 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX82207.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX82207.1 - 0.24 11.7 4.5 5.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82208.1 - 2.3e-33 114.4 0.6 4.8e-33 113.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82208.1 - 0.034 14.8 0.0 0.094 13.3 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX82208.1 - 0.2 12.4 1.4 11 6.8 0.3 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 LOH1CR12 PF10158.9 EAX82208.1 - 1 9.4 4.6 2.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Glycos_transf_2 PF00535.26 EAX82209.1 - 0.015 15.1 0.0 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 Staphostatin_B PF09023.10 EAX82210.1 - 0.17 11.9 3.7 0.086 12.9 1.0 1.9 2 0 0 2 2 2 0 Staphostatin B DUF3839 PF12943.7 EAX82211.1 - 4.7e-158 523.9 13.3 5.9e-158 523.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82211.1 - 0.13 12.1 1.0 0.4 10.5 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82211.1 - 1.4 9.4 4.8 4.9 7.7 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX82212.1 - 4.9e-09 36.0 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX82212.1 - 0.15 11.4 0.2 0.3 10.5 0.2 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX82212.1 - 1.2 9.5 4.7 4.2 7.7 0.4 2.3 1 1 0 2 2 2 0 PRD domain EssA PF10661.9 EAX82212.1 - 3.5 7.4 7.8 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX82214.1 - 2.2e-145 482.4 11.5 2.6e-145 482.2 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82214.1 - 0.68 10.4 3.7 2 8.9 1.2 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX82214.1 - 1.5 9.5 5.3 4 8.1 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Gly-zipper_Omp PF13488.6 EAX82215.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX82215.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Antimicrobial_8 PF08103.11 EAX82217.1 - 8.5 6.7 6.3 1.7 8.9 0.6 2.8 2 0 0 2 2 2 0 Uperin family DUF3839 PF12943.7 EAX82219.1 - 4.4e-157 520.7 13.6 5.4e-157 520.4 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82219.1 - 0.085 13.3 1.3 0.16 12.4 0.2 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82219.1 - 0.75 10.3 7.3 3.5 8.1 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX82220.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX82221.1 - 0.031 14.7 0.9 0.074 13.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX82223.1 - 2.9e-71 238.9 4.5 3.5e-71 238.6 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX82225.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82225.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82225.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82225.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82225.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82225.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82225.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82225.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82225.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82225.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82225.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82225.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3213 PF11491.8 EAX82226.1 - 0.022 14.9 0.5 0.056 13.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DDR PF08841.10 EAX82227.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX82228.1 - 6.8e-73 244.2 3.8 8.7e-73 243.8 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX82229.1 - 3e-44 149.4 0.5 7e-44 148.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3552 PF12072.8 EAX82229.1 - 0.014 14.9 7.1 0.024 14.1 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3213 PF11491.8 EAX82229.1 - 0.12 12.6 3.9 4.9 7.4 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3213) RRP36 PF06102.12 EAX82229.1 - 0.13 12.3 6.5 0.27 11.2 6.5 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Pox_A32 PF04665.12 EAX82230.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82230.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX82230.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX82230.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82230.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX82230.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF4107 PF13389.6 EAX82231.1 - 3.4e-22 79.3 1.2 3.7e-22 79.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ABC_tran PF00005.27 EAX82233.1 - 9.4e-23 81.2 0.3 2.4e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAX82233.1 - 1.3e-05 25.2 9.7 0.013 15.3 0.1 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EAX82233.1 - 0.0059 15.9 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 EAX82233.1 - 0.0086 16.0 0.8 0.017 15.1 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EAX82233.1 - 0.082 12.3 1.9 1.8 7.9 0.0 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAX82233.1 - 0.13 12.6 0.1 2.4 8.4 0.0 2.7 2 2 0 2 2 2 0 AAA domain AAA PF00004.29 EAX82233.1 - 0.4 11.1 2.1 2.2 8.7 0.2 3.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MAP PF03642.13 EAX82233.1 - 1.7 9.0 8.3 0.83 10.0 0.1 3.6 3 0 0 3 3 3 0 MAP domain DUF3839 PF12943.7 EAX82234.1 - 3.2e-155 514.7 12.3 4e-155 514.3 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82234.1 - 2.8 8.5 5.7 1.5 9.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82234.1 - 4.9 7.7 8.4 2.1 8.9 0.7 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 EAX82235.1 - 1.1e-112 368.8 10.4 4.6e-20 72.0 0.0 5.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX82235.1 - 6.5e-56 184.5 0.0 3.6e-06 27.2 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX82235.1 - 6.1e-49 163.4 1.5 1.5e-08 34.7 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX82235.1 - 1.6e-47 159.2 0.0 7.2e-10 39.2 0.0 5.5 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82235.1 - 2.8e-43 140.9 0.1 0.0014 18.9 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat L_protein_N PF15518.6 EAX82235.1 - 3.1e-06 26.9 0.9 18 5.2 0.0 6.7 2 1 5 7 7 7 1 L protein N-terminus DUF4515 PF14988.6 EAX82235.1 - 0.056 13.3 4.1 0.048 13.5 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Gly-zipper_Omp PF13488.6 EAX82236.1 - 0.0058 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX82236.1 - 0.28 11.5 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82236.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX82239.1 - 6.4e-151 500.6 14.3 7.8e-151 500.3 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82239.1 - 0.47 10.9 4.6 1.9 9.0 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82239.1 - 1.1 9.6 5.2 11 6.4 0.0 3.7 4 1 0 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX82240.1 - 1.5e-34 118.2 0.1 2e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX82240.1 - 0.093 12.7 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon KilA-N PF04383.13 EAX82241.1 - 1.3e-34 118.4 1.2 1.8e-34 118.0 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain PLAC8 PF04749.17 EAX82244.1 - 2e-13 51.2 26.3 2.7e-13 50.8 26.3 1.2 1 0 0 1 1 1 1 PLAC8 family KilA-N PF04383.13 EAX82245.1 - 2.4e-40 136.9 0.4 5.5e-40 135.7 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82245.1 - 0.029 15.0 0.2 0.1 13.2 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family ANAPC15 PF15243.6 EAX82245.1 - 0.12 12.8 2.8 0.15 12.5 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Pox_A32 PF04665.12 EAX82246.1 - 6.1e-07 29.1 2.5 6.1e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82246.1 - 4.3e-05 23.3 0.2 0.41 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82246.1 - 6.1e-05 23.3 0.2 0.00039 20.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82246.1 - 9.2e-05 22.5 3.2 0.00021 21.3 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82246.1 - 0.00057 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82246.1 - 0.0022 17.8 0.5 0.004 17.0 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82246.1 - 0.0025 17.5 0.4 0.017 14.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82246.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82246.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82246.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82246.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82246.1 - 0.29 11.4 3.8 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX82247.1 - 3.3e-28 97.5 27.6 5.6e-25 87.2 7.0 4.5 5 0 0 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX82247.1 - 0.022 15.3 10.1 1.5 9.4 1.3 3.5 3 1 0 3 3 3 0 YmaF family DUF4116 PF13475.6 EAX82247.1 - 0.038 13.7 0.1 0.093 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX82247.1 - 0.083 13.4 1.3 0.25 11.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF1493 PF07377.12 EAX82248.1 - 0.051 14.0 0.5 0.1 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2939 PF11159.8 EAX82249.1 - 0.084 13.3 0.2 0.12 12.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Tctex-1 PF03645.13 EAX82249.1 - 0.12 12.7 0.3 0.16 12.2 0.3 1.2 1 0 0 1 1 1 0 Tctex-1 family FAS_N PF17828.1 EAX82250.1 - 0.017 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KilA-N PF04383.13 EAX82252.1 - 0.0098 15.7 0.6 0.029 14.2 0.6 1.9 1 1 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX82252.1 - 0.014 16.0 0.1 0.025 15.1 0.1 1.5 1 0 0 1 1 1 0 T5orf172 domain Lectin_legB PF00139.19 EAX82252.1 - 0.089 12.3 0.3 0.17 11.4 0.2 1.4 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX82253.1 - 7.9e-06 25.7 0.6 1.4e-05 24.9 0.0 1.7 2 1 0 2 2 2 1 KilA-N domain Actin PF00022.19 EAX82254.1 - 6.8e-85 285.1 0.0 3.5e-84 282.8 0.0 1.8 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX82254.1 - 0.044 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT DUF724 PF05266.14 EAX82255.1 - 1.6e-05 24.8 15.4 2.3e-05 24.3 15.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 EAX82255.1 - 0.00015 21.8 18.0 0.00015 21.8 18.0 1.4 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EAX82255.1 - 0.00028 21.2 9.1 0.00042 20.6 9.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EAX82255.1 - 0.0043 16.5 4.5 0.0045 16.4 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EAX82255.1 - 0.006 16.8 16.9 0.16 12.2 6.8 2.4 1 1 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EAX82255.1 - 0.0064 16.2 24.3 0.046 13.5 3.0 3.6 1 1 2 3 3 3 2 Septum formation initiator CEP63 PF17045.5 EAX82255.1 - 0.0078 16.1 16.1 0.15 11.9 7.7 2.1 1 1 1 2 2 2 2 Centrosomal protein of 63 kDa Vps4_C PF09336.10 EAX82255.1 - 0.039 14.0 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Rootletin PF15035.6 EAX82255.1 - 0.13 12.3 9.5 0.2 11.7 9.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 EAX82255.1 - 0.2 11.3 23.2 0.37 10.4 3.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SIKE PF05769.11 EAX82255.1 - 0.3 11.0 20.6 20 5.0 19.4 2.5 1 1 0 1 1 1 0 SIKE family Xrn1_D3 PF18194.1 EAX82255.1 - 0.54 10.4 7.0 0.85 9.8 0.1 3.7 3 1 1 4 4 4 0 Exoribonuclease 1 Domain-3 Tropomyosin_1 PF12718.7 EAX82255.1 - 0.57 10.3 22.6 1.3 9.2 4.5 2.2 1 1 1 2 2 2 0 Tropomyosin like UPF0242 PF06785.11 EAX82255.1 - 0.58 10.2 20.3 2.6 8.1 20.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3573 PF12097.8 EAX82255.1 - 0.8 8.5 8.8 0.99 8.2 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4291 PF14124.6 EAX82255.1 - 0.84 9.5 7.4 1.6 8.6 5.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4291) CALCOCO1 PF07888.11 EAX82255.1 - 0.86 8.4 15.6 1.7 7.4 15.6 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ABC_tran_CTD PF16326.5 EAX82255.1 - 0.86 9.9 16.2 2.9 8.2 0.9 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain HemX PF04375.14 EAX82255.1 - 0.89 8.8 12.2 0.12 11.6 0.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fez1 PF06818.15 EAX82255.1 - 1 9.8 16.5 7.1 7.0 16.0 2.0 1 1 1 2 2 2 0 Fez1 SlyX PF04102.12 EAX82255.1 - 1 10.0 8.6 2.5 8.8 0.4 2.9 1 1 1 2 2 2 0 SlyX Atg14 PF10186.9 EAX82255.1 - 1.1 8.2 21.0 6.7 5.7 4.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PCRF PF03462.18 EAX82255.1 - 2.3 8.1 14.6 0.067 13.0 1.6 2.1 1 1 1 2 2 2 0 PCRF domain APG6_N PF17675.1 EAX82255.1 - 4 8.0 19.5 0.82 10.2 3.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3847 PF12958.7 EAX82255.1 - 4.4 7.5 16.9 28 4.9 1.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3847) FlxA PF14282.6 EAX82255.1 - 4.8 7.2 18.0 2.7 8.1 11.2 2.4 1 1 1 2 2 2 0 FlxA-like protein Med9 PF07544.13 EAX82255.1 - 4.9 7.3 18.7 1.2 9.2 3.4 3.4 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF5595 PF18077.1 EAX82255.1 - 5.2 7.2 16.3 2.9 8.0 1.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) TMF_DNA_bd PF12329.8 EAX82255.1 - 5.2 7.1 30.0 17 5.5 6.1 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 EAX82255.1 - 5.8 7.1 14.3 3.2 7.9 5.9 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF641 PF04859.12 EAX82255.1 - 6.8 7.0 16.2 11 6.3 11.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Geminin PF07412.12 EAX82255.1 - 8.5 6.1 21.5 0.053 13.3 4.8 3.0 1 1 1 3 3 3 0 Geminin Spc7 PF08317.11 EAX82255.1 - 8.7 5.1 22.9 8.7 5.1 21.3 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3839 PF12943.7 EAX82257.1 - 3.6e-154 511.2 12.6 4.7e-154 510.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82257.1 - 0.064 13.8 2.0 0.51 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) MitMem_reg PF13012.6 EAX82257.1 - 0.13 12.7 0.4 0.57 10.6 0.1 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX82257.1 - 0.42 11.1 3.7 11 6.6 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82257.1 - 1.2 9.5 4.8 15 6.0 0.1 3.7 4 1 1 5 5 5 0 Tup N-terminal Pox_A32 PF04665.12 EAX82258.1 - 1.3e-07 31.4 0.9 1.5e-07 31.2 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82258.1 - 0.003 17.2 0.1 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX82258.1 - 0.0099 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase RnlB_antitoxin PF15933.5 EAX82258.1 - 0.049 13.9 1.1 0.13 12.5 0.3 1.9 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA IstB_IS21 PF01695.17 EAX82258.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82258.1 - 0.097 12.6 0.3 0.76 9.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX82259.1 - 5.9e-40 135.6 0.6 1.4e-39 134.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82259.1 - 0.013 16.1 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX82260.1 - 2.2e-07 31.4 0.3 4.5e-07 30.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX82260.1 - 0.13 13.0 0.4 0.34 11.6 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Adaptin_N PF01602.20 EAX82262.1 - 7.9e-76 255.7 2.2 1e-75 255.3 2.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EAX82262.1 - 2.2e-05 24.6 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 EAX82262.1 - 0.00014 21.9 0.1 0.48 10.4 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX82262.1 - 0.0039 17.3 0.4 64 4.2 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat DUF5578 PF17741.1 EAX82262.1 - 0.1 12.0 5.9 0.71 9.2 0.1 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5578) DUF3772 PF12607.8 EAX82262.1 - 0.27 11.0 1.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) PTR PF12789.7 EAX82263.1 - 2.3e-29 101.2 11.7 2.3e-29 101.2 11.7 3.6 5 0 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX82263.1 - 0.089 12.5 3.0 0.095 12.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX82263.1 - 4.1 7.4 8.5 2.6 8.0 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX82264.1 - 0.023 15.1 1.0 0.044 14.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Trypan_PARP PF05887.11 EAX82265.1 - 0.04 13.9 8.4 0.054 13.5 8.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX82267.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX82269.1 - 6.9e-36 122.5 0.0 1.7e-35 121.3 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX82269.1 - 0.0041 17.7 0.1 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX82270.1 - 8.8e-07 28.6 1.8 1.3e-06 28.0 1.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82270.1 - 0.0042 16.7 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX82270.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX82270.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82270.1 - 0.061 13.1 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82270.1 - 0.094 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX82270.1 - 0.54 10.5 8.3 5.3 7.3 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX82271.1 - 9.3e-154 509.9 13.3 1.1e-153 509.7 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82271.1 - 0.15 12.0 1.8 0.45 10.4 0.6 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82271.1 - 0.28 11.7 4.6 3.5 8.1 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COX15-CtaA PF02628.15 EAX82272.1 - 0.0073 15.4 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein LELP1 PF15042.6 EAX82272.1 - 0.82 10.1 3.1 0.5 10.8 1.4 1.5 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Myb_DNA-binding PF00249.31 EAX82273.1 - 3.8e-20 71.8 1.7 1.6e-09 37.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82273.1 - 1e-18 67.3 0.5 1.2e-09 38.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX82273.1 - 1.1e-06 28.4 4.4 5.6e-06 26.2 4.5 2.1 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX82273.1 - 0.0078 16.6 8.9 0.73 10.3 0.0 3.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EAX82273.1 - 0.067 13.2 5.6 0.3 11.1 0.1 3.0 1 1 1 2 2 2 0 SLIDE MADF_DNA_bdg PF10545.9 EAX82273.1 - 0.15 12.4 0.3 0.15 12.4 0.3 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TPR_MLP1_2 PF07926.12 EAX82274.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX82274.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82274.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family EpuA PF11772.8 EAX82275.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX82275.1 - 0.44 10.6 0.0 0.44 10.6 0.0 3.1 5 0 0 5 5 5 0 Phage tail repeat like Lsm_C PF14894.6 EAX82278.1 - 0.0054 16.5 25.0 2.4e+02 1.6 0.0 11.8 13 0 0 13 13 13 0 Lsm C-terminal GPS2_interact PF15784.5 EAX82279.1 - 0.029 14.8 0.5 0.036 14.5 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX82280.1 - 0.083 12.8 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) KilA-N PF04383.13 EAX82281.1 - 4.6e-31 107.0 0.7 9.2e-31 106.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF4108 PF13390.6 EAX82282.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX82283.1 - 1.9e-55 186.7 7.5 2.2e-55 186.5 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX82285.1 - 1.4e-07 31.2 0.9 6.9e-07 29.0 0.1 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX82285.1 - 0.061 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX82285.1 - 0.099 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX82285.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX82287.1 - 7.4e-34 116.0 0.6 1.6e-33 114.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82287.1 - 0.057 14.0 0.0 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX82287.1 - 0.13 12.9 1.8 9.6 7.0 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX82288.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82288.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82288.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82288.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82288.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX82288.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82288.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PapD_N PF00345.20 EAX82290.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX82291.1 - 5.1e-24 85.0 7.9 3e-23 82.4 7.9 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX82291.1 - 0.085 12.9 0.1 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX82292.1 - 2.2e-25 89.6 4.6 3.2e-25 89.0 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX82292.1 - 0.14 12.6 0.6 0.35 11.3 0.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX82293.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82293.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82293.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82293.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82293.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82293.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82293.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82293.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82293.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82293.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82293.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82293.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX82295.1 - 8.2e-62 207.4 8.3 9.1e-62 207.2 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX82295.1 - 0.11 12.7 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4108 PF13390.6 EAX82296.1 - 5.5e-63 211.2 6.1 6.1e-63 211.0 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) NMT PF01233.19 EAX82297.1 - 2.5 7.9 6.0 0.19 11.6 0.8 1.7 2 1 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain T5orf172 PF10544.9 EAX82298.1 - 0.00019 21.9 0.3 0.00043 20.8 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX82298.1 - 0.0057 16.2 0.9 0.069 12.7 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX82298.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain T5orf172 PF10544.9 EAX82300.1 - 3.5e-07 30.7 1.3 7e-07 29.7 0.4 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX82300.1 - 0.0065 16.0 0.4 0.11 12.1 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain Baculo_ME53 PF06061.11 EAX82300.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF5623 PF18536.1 EAX82301.1 - 0.081 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX82301.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Myb_DNA-binding PF00249.31 EAX82302.1 - 1e-27 96.0 1.2 9e-15 54.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82302.1 - 1.8e-24 85.8 4.2 1.7e-17 63.4 0.2 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX82302.1 - 2.3e-06 27.6 3.1 0.00046 20.2 0.4 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX82302.1 - 0.00016 21.5 1.5 0.078 12.9 0.1 2.8 1 1 2 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX82302.1 - 0.016 15.4 0.3 0.39 10.9 0.1 2.6 1 1 1 2 2 2 0 Rap1 Myb domain Phage_RpbA PF10789.9 EAX82302.1 - 0.021 14.9 0.8 7 6.8 0.1 2.2 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Myb_DNA-bind_4 PF13837.6 EAX82302.1 - 0.53 10.7 5.0 5.7 7.4 0.6 3.2 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EAX82302.1 - 8.2 6.6 8.7 26 5.0 0.1 3.9 2 2 3 5 5 5 0 Myb/SANT-like DNA-binding domain LRR_5 PF13306.6 EAX82303.1 - 9.2e-11 41.8 3.8 6.8e-07 29.3 1.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) IBR PF01485.21 EAX82307.1 - 4.2e-06 26.9 10.9 4.2e-06 26.9 10.9 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain HTH_16 PF12645.7 EAX82307.1 - 0.059 13.4 0.6 8 6.6 0.2 3.3 2 1 1 3 3 3 0 Helix-turn-helix domain DUF3924 PF13062.6 EAX82307.1 - 0.12 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) ITI_HC_C PF06668.12 EAX82307.1 - 0.15 11.7 3.1 0.33 10.6 3.1 1.5 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus zf-C2H2_4 PF13894.6 EAX82307.1 - 0.25 12.3 0.1 0.25 12.3 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger DUF3073 PF11273.8 EAX82308.1 - 0.087 13.6 0.1 0.14 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) IL1 PF00340.19 EAX82309.1 - 0.028 14.1 0.2 0.035 13.7 0.2 1.3 1 1 0 1 1 1 0 Interleukin-1 / 18 DUF4028 PF13220.6 EAX82309.1 - 0.091 12.5 0.7 0.19 11.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4028) Ank_2 PF12796.7 EAX82310.1 - 1.9e-12 47.6 0.1 2.3e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82310.1 - 8.3e-12 45.4 0.3 2.6e-08 34.3 0.2 2.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX82310.1 - 1.2e-08 35.1 0.8 2.8e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX82310.1 - 1.8e-07 31.3 0.0 0.0014 19.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX82310.1 - 6.6e-06 26.1 0.0 0.0055 17.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF3781 PF12636.7 EAX82311.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX82312.1 - 5.2e-30 104.7 4.5 4.7e-28 98.4 4.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) EB1 PF03271.17 EAX82313.1 - 1.4e-10 41.2 1.0 3.6e-10 39.9 1.0 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EAX82313.1 - 6.9e-10 39.1 0.3 1.5e-09 38.0 0.3 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EAX82313.1 - 6.3e-05 23.0 0.2 0.00019 21.5 0.2 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EAX82313.1 - 0.00097 18.9 0.2 0.0022 17.8 0.2 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CLZ PF16526.5 EAX82313.1 - 0.079 13.3 1.9 0.2 12.0 1.9 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KilA-N PF04383.13 EAX82314.1 - 5.6e-14 51.9 0.2 1e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX82314.1 - 0.0098 15.8 1.2 0.064 13.2 0.0 2.5 2 1 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX82315.1 - 4.9e-152 504.2 11.9 6e-152 503.9 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82315.1 - 0.026 14.4 0.7 0.073 12.9 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX82315.1 - 0.14 12.7 3.9 0.28 11.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX82315.1 - 0.17 12.2 0.6 0.67 10.3 0.2 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Pox_A32 PF04665.12 EAX82316.1 - 7.2e-07 28.9 2.3 7.2e-07 28.9 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82316.1 - 2.8e-05 24.4 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82316.1 - 0.00016 21.7 3.1 0.00034 20.7 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX82316.1 - 0.00017 21.3 0.2 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX82316.1 - 0.00055 19.7 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82316.1 - 0.0017 18.2 0.8 0.0034 17.2 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82316.1 - 0.0019 17.9 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82316.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX82316.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX82316.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX82316.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82316.1 - 0.088 13.2 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4108 PF13390.6 EAX82318.1 - 1e-55 187.6 7.7 1.1e-55 187.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX82319.1 - 0.00014 22.3 2.2 0.00076 19.9 2.2 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82319.1 - 0.043 14.4 0.1 0.089 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82319.1 - 0.083 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Tetraspanin PF00335.20 EAX82320.1 - 0.01 15.5 0.4 0.01 15.5 0.4 1.7 1 1 0 1 1 1 0 Tetraspanin family Protocadherin PF08374.11 EAX82320.1 - 0.054 13.5 0.6 2.3 8.1 0.0 2.4 1 1 2 3 3 3 0 Protocadherin Wzy_C PF04932.15 EAX82320.1 - 0.58 9.8 5.9 2.3 7.8 6.2 1.9 1 1 0 1 1 1 0 O-Antigen ligase DUF4795 PF16043.5 EAX82321.1 - 4.9e-06 26.3 17.2 0.028 14.0 0.9 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) Glyco_transf_49 PF13896.6 EAX82321.1 - 0.0066 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan SEP PF08059.13 EAX82321.1 - 0.21 12.1 3.8 6.4 7.4 1.1 2.7 1 1 1 2 2 2 0 SEP domain Phage_fiber PF03335.13 EAX82321.1 - 0.69 10.2 9.8 0.27 11.5 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat Laminin_I PF06008.14 EAX82322.1 - 6.3e-10 39.2 24.1 0.0014 18.4 5.5 3.6 1 1 2 3 3 3 3 Laminin Domain I KASH_CCD PF14662.6 EAX82322.1 - 7.5e-06 25.9 22.6 0.0028 17.5 4.6 2.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX82322.1 - 8.9e-06 25.3 15.1 0.84 9.0 0.4 4.3 1 1 3 4 4 4 4 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 EAX82322.1 - 2.4e-05 24.6 22.3 0.013 15.7 3.2 3.2 1 1 2 3 3 3 3 JNK_SAPK-associated protein-1 GCN5L1 PF06320.13 EAX82322.1 - 7.8e-05 22.8 8.9 3 8.0 0.7 4.3 1 1 3 4 4 4 2 GCN5-like protein 1 (GCN5L1) Sec34 PF04136.15 EAX82322.1 - 0.0001 22.2 40.1 0.099 12.5 7.5 4.8 1 1 5 6 6 6 6 Sec34-like family ERM PF00769.19 EAX82322.1 - 0.00018 21.4 9.4 0.087 12.6 1.3 2.8 1 1 1 2 2 2 2 Ezrin/radixin/moesin family ZapB PF06005.12 EAX82322.1 - 0.00039 20.8 10.7 1.6 9.2 0.2 4.7 1 1 3 4 4 4 1 Cell division protein ZapB Spc7 PF08317.11 EAX82322.1 - 0.0005 19.0 21.7 0.1 11.5 5.4 2.6 1 1 2 3 3 3 3 Spc7 kinetochore protein YabA PF06156.13 EAX82322.1 - 0.00051 20.6 6.2 2.3 8.9 0.2 3.7 1 1 1 2 2 2 2 Initiation control protein YabA BRE1 PF08647.11 EAX82322.1 - 0.0017 18.4 19.3 0.41 10.8 0.9 4.0 1 1 3 4 4 4 3 BRE1 E3 ubiquitin ligase UPF0449 PF15136.6 EAX82322.1 - 0.002 18.6 21.5 0.4 11.2 2.2 4.7 1 1 2 3 3 3 2 Uncharacterised protein family UPF0449 Ax_dynein_light PF10211.9 EAX82322.1 - 0.0031 17.5 5.2 4.4 7.2 0.2 3.8 1 1 3 4 4 4 1 Axonemal dynein light chain BLOC1_2 PF10046.9 EAX82322.1 - 0.008 16.5 22.1 1.8 8.9 4.1 5.1 1 1 3 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 EAX82322.1 - 0.0084 16.3 9.6 33 4.8 0.1 5.5 1 1 5 7 7 7 0 JNK-interacting protein leucine zipper II Laminin_II PF06009.12 EAX82322.1 - 0.013 15.5 25.2 0.15 12.1 3.9 3.8 1 1 3 4 4 4 0 Laminin Domain II COG7 PF10191.9 EAX82322.1 - 0.022 13.0 29.0 0.098 10.9 7.1 3.3 1 1 3 4 4 4 0 Golgi complex component 7 (COG7) APG6_N PF17675.1 EAX82322.1 - 0.033 14.7 25.6 10 6.7 13.8 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 EAX82322.1 - 0.038 14.0 15.3 1.8 8.6 1.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EAX82322.1 - 0.043 13.9 38.4 0.32 11.1 15.4 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAX82322.1 - 0.1 12.6 17.8 0.75 9.8 3.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 EAX82322.1 - 0.24 10.7 41.5 0.15 11.3 9.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 EAX82322.1 - 0.3 10.6 30.0 1.3 8.5 12.3 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Prominin PF05478.11 EAX82322.1 - 0.32 8.9 23.4 1.1 7.2 6.2 2.9 1 1 2 3 3 3 0 Prominin DUF948 PF06103.11 EAX82322.1 - 0.7 10.2 7.9 19 5.6 0.9 3.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 EAX82322.1 - 0.76 9.5 6.5 16 5.2 0.4 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) CheZ PF04344.13 EAX82322.1 - 0.87 9.5 17.8 2.7 7.9 3.9 3.1 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ Tropomyosin_1 PF12718.7 EAX82322.1 - 1.1 9.4 14.5 12 6.1 0.9 3.5 1 1 3 4 4 4 0 Tropomyosin like DUF724 PF05266.14 EAX82322.1 - 1.7 8.5 15.3 4.8 7.0 4.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 EAX82322.1 - 2.2 7.4 23.9 1.3 8.2 3.5 3.0 1 1 1 3 3 3 0 TMPIT-like protein Occludin_ELL PF07303.13 EAX82322.1 - 2.4 8.9 9.5 41 5.0 0.1 4.2 1 1 2 4 4 4 0 Occludin homology domain Fib_alpha PF08702.10 EAX82322.1 - 2.4 8.3 19.3 10 6.3 3.0 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 EAX82322.1 - 4.6 7.2 14.1 40 4.1 0.4 4.9 1 1 3 5 5 5 0 Prefoldin subunit TACC_C PF05010.14 EAX82322.1 - 5 6.9 10.4 12 5.6 2.6 2.7 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Gly_rich PF12810.7 EAX82324.1 - 4.6e-32 111.9 34.5 7.7e-32 111.1 34.5 1.2 1 0 0 1 1 1 1 Glycine rich protein Furin-like_2 PF15913.5 EAX82324.1 - 0.0012 19.0 25.1 0.043 14.0 6.1 2.3 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EAX82324.1 - 0.12 11.2 25.6 0.075 11.9 23.0 1.9 2 1 0 2 2 2 0 Giardia variant-specific surface protein TMEM154 PF15102.6 EAX82325.1 - 0.00022 21.2 6.2 0.0003 20.7 6.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 EAX82325.1 - 0.00049 20.1 0.8 0.00058 19.8 0.8 1.1 1 0 0 1 1 1 1 Rifin DUF5305 PF17231.2 EAX82325.1 - 0.00056 19.4 3.5 0.0009 18.7 3.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) ETRAMP PF09716.10 EAX82325.1 - 0.0013 18.8 1.0 0.0019 18.3 1.0 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) PIRT PF15099.6 EAX82325.1 - 0.0022 17.6 5.4 0.003 17.1 5.0 1.4 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family ASFV_J13L PF05568.11 EAX82325.1 - 0.003 17.4 1.4 0.003 17.4 1.4 1.5 2 0 0 2 2 2 1 African swine fever virus J13L protein DUF4064 PF13273.6 EAX82325.1 - 0.0074 16.5 0.5 0.014 15.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Orf78 PF06024.12 EAX82325.1 - 0.0075 16.6 2.5 0.016 15.5 2.5 1.6 1 1 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 EAX82325.1 - 0.0089 14.8 0.0 0.0091 14.8 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Sec3_C PF09763.9 EAX82325.1 - 0.015 13.7 1.0 0.016 13.6 1.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 HRG PF16954.5 EAX82325.1 - 0.036 14.5 0.1 0.059 13.8 0.1 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Sigma_reg_N PF13800.6 EAX82325.1 - 0.038 14.3 3.3 0.07 13.4 3.3 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syndecan PF01034.20 EAX82325.1 - 0.05 13.5 1.2 0.08 12.9 1.2 1.3 1 0 0 1 1 1 0 Syndecan domain Pox_A14 PF05767.12 EAX82325.1 - 0.051 13.7 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_M56 PF05569.11 EAX82325.1 - 0.065 12.4 0.1 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Viral_Beta_CD PF04530.12 EAX82325.1 - 0.072 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family TRP PF06011.12 EAX82325.1 - 0.089 11.5 0.2 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 EAX82325.1 - 0.1 13.5 0.3 0.18 12.7 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0239 PF06783.11 EAX82325.1 - 0.16 12.2 4.2 0.3 11.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) ECSCR PF15820.5 EAX82325.1 - 0.38 10.6 4.4 0.11 12.3 0.9 1.8 1 1 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FAM163 PF15069.6 EAX82325.1 - 0.48 10.9 2.3 0.39 11.1 0.3 1.8 1 1 1 2 2 2 0 FAM163 family Shisa PF13908.6 EAX82325.1 - 1.9 8.7 7.3 3.9 7.7 1.3 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator KilA-N PF04383.13 EAX82326.1 - 5.1e-22 77.8 0.3 9.7e-22 76.9 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX82326.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX82326.1 - 0.2 11.1 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain TPR_MLP1_2 PF07926.12 EAX82327.1 - 0.027 14.5 0.2 0.031 14.3 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX82327.1 - 0.085 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82327.1 - 0.47 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX82328.1 - 1.3e-155 515.9 13.5 1.7e-155 515.6 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82328.1 - 0.021 14.7 0.8 0.084 12.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX82328.1 - 0.072 13.4 0.4 1.5 9.1 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX82328.1 - 0.1 13.0 0.3 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX82328.1 - 1.5 9.3 7.7 2.1 8.8 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82329.1 - 1.8e-07 31.7 0.3 3.3e-07 30.8 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX82330.1 - 2.9e-156 518.1 12.6 3.7e-156 517.7 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82330.1 - 0.12 12.3 0.8 0.35 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Laminin_I PF06008.14 EAX82331.1 - 7.3e-09 35.7 27.5 0.018 14.8 4.8 3.8 1 1 4 5 5 5 5 Laminin Domain I KASH_CCD PF14662.6 EAX82331.1 - 0.0091 15.8 24.1 0.07 12.9 12.4 2.4 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH RNase_E_G PF10150.9 EAX82331.1 - 0.012 15.0 6.3 2.8 7.3 0.5 3.0 1 1 1 3 3 3 0 Ribonuclease E/G family Sec34 PF04136.15 EAX82331.1 - 0.014 15.3 49.3 0.36 10.7 5.2 5.3 1 1 4 5 5 5 0 Sec34-like family YabA PF06156.13 EAX82331.1 - 0.092 13.4 12.3 17 6.1 0.4 4.1 1 1 3 4 4 4 0 Initiation control protein YabA Ax_dynein_light PF10211.9 EAX82331.1 - 0.1 12.5 5.7 10 6.0 0.1 3.6 1 1 3 4 4 4 0 Axonemal dynein light chain UPF0449 PF15136.6 EAX82331.1 - 0.11 13.0 24.1 2.1 8.9 0.3 4.6 1 1 4 5 5 5 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 EAX82331.1 - 0.18 12.3 10.3 20 5.7 0.1 4.3 2 1 2 4 4 4 0 Cell division protein ZapB BRE1 PF08647.11 EAX82331.1 - 0.39 10.8 19.7 1.7 8.8 1.8 4.0 1 1 4 5 5 5 0 BRE1 E3 ubiquitin ligase DUF3552 PF12072.8 EAX82331.1 - 0.86 9.0 15.3 3.8 6.9 1.9 3.9 1 1 4 5 5 5 0 Domain of unknown function (DUF3552) DUF948 PF06103.11 EAX82331.1 - 0.94 9.8 8.8 44 4.4 1.8 4.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 EAX82331.1 - 0.98 9.5 41.2 2 8.5 13.7 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 EAX82331.1 - 1.1 9.0 10.4 9.4 6.0 0.2 3.0 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 EAX82331.1 - 2.3 8.2 24.7 1.5 8.8 3.5 4.0 1 1 3 4 4 4 0 Laminin Domain II GPS2_interact PF15784.5 EAX82331.1 - 2.5 8.6 6.4 14 6.2 1.2 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Jnk-SapK_ap_N PF09744.9 EAX82331.1 - 3 8.1 32.1 2.6 8.2 4.7 4.3 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 EAX82331.1 - 9.2 4.7 36.6 1.6 7.2 25.0 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family KilA-N PF04383.13 EAX82332.1 - 8.9e-34 115.7 1.1 1.4e-33 115.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82332.1 - 0.024 15.2 0.0 0.074 13.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX82333.1 - 7e-07 29.7 0.3 1.8e-06 28.4 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82333.1 - 0.0059 16.4 0.1 0.036 13.9 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX82333.1 - 0.01 15.4 0.2 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4107 PF13389.6 EAX82335.1 - 6.2e-73 244.3 3.9 7.9e-73 244.0 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX82336.1 - 0.0033 17.1 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase ComA PF02679.15 EAX82337.1 - 0.06 12.8 0.5 0.074 12.5 0.5 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) MtrG PF04210.13 EAX82337.1 - 0.22 11.4 0.6 0.43 10.5 0.2 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3839 PF12943.7 EAX82338.1 - 8.8e-156 516.5 13.5 1.1e-155 516.2 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82338.1 - 0.05 14.2 4.5 0.46 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82338.1 - 0.32 11.5 7.5 1.7 9.2 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX82339.1 - 1.9e-61 206.2 7.0 2.1e-61 206.0 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Dsh_C PF12316.8 EAX82341.1 - 1.4 9.3 8.8 1.6 9.1 8.8 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SprA-related PF12118.8 EAX82341.1 - 9.3 5.3 14.2 11 5.0 14.2 1.0 1 0 0 1 1 1 0 SprA-related family PTR PF12789.7 EAX82342.1 - 4.2e-11 42.7 4.2 2.1e-09 37.3 0.4 4.3 5 0 0 5 5 5 2 Phage tail repeat like BRO1 PF03097.18 EAX82342.1 - 0.049 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain LegC3_N PF18654.1 EAX82342.1 - 0.42 9.8 3.5 0.21 10.8 0.9 1.7 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain YmaF PF12788.7 EAX82342.1 - 0.55 10.8 9.1 26 5.4 0.0 4.0 4 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX82342.1 - 2.9 7.5 9.9 1.6 8.3 2.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3781 PF12636.7 EAX82343.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX82345.1 - 1e-154 513.0 12.9 1.2e-154 512.8 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX82345.1 - 0.013 15.5 0.6 5.5 7.0 0.0 2.6 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NTP_transf_6 PF06042.11 EAX82345.1 - 0.11 12.3 0.7 0.23 11.3 0.4 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase Tup_N PF08581.10 EAX82345.1 - 0.17 12.2 2.2 14 6.0 0.0 3.2 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX82345.1 - 0.31 11.5 5.4 0.87 10.1 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Annexin PF00191.20 EAX82346.1 - 0.049 13.7 0.3 0.073 13.2 0.2 1.4 1 1 0 1 1 1 0 Annexin DUF1031 PF06275.11 EAX82346.1 - 0.076 13.3 0.1 0.091 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) HARE-HTH PF05066.13 EAX82346.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain PepSY_TM_like_2 PF16357.5 EAX82346.1 - 0.24 11.3 0.5 0.27 11.2 0.5 1.0 1 0 0 1 1 1 0 Putative PepSY_TM-like Pox_A32 PF04665.12 EAX82348.1 - 5.3e-05 22.8 3.0 8.5e-05 22.1 3.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX82348.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX82348.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX82348.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1493 PF07377.12 EAX82351.1 - 0.057 13.9 0.6 0.13 12.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX82352.1 - 5.2e-79 260.2 53.6 2e-31 107.8 13.4 4.5 2 2 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX82352.1 - 0.036 13.8 0.9 0.069 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX82352.1 - 0.14 11.6 4.6 0.52 9.7 0.7 2.3 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF4795 PF16043.5 EAX82352.1 - 0.3 10.7 13.3 1.1 8.9 12.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX82353.1 - 2.6e-154 511.7 13.4 3.3e-154 511.4 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82353.1 - 0.03 14.8 2.3 0.11 13.0 0.4 2.1 2 0 0 2 2 2 0 Fez1 PRD PF00874.20 EAX82353.1 - 0.33 11.3 4.3 1 9.7 0.0 3.2 2 2 0 2 2 2 0 PRD domain KELK PF15796.5 EAX82353.1 - 0.85 10.1 8.0 1.8 9.1 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82353.1 - 2.6 8.6 8.1 0.38 11.3 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX82353.1 - 3 8.2 5.9 9 6.6 0.1 3.4 2 2 0 2 2 2 0 Rx N-terminal domain Ank_2 PF12796.7 EAX82354.1 - 1.1e-27 96.4 5.5 2.5e-17 63.2 1.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX82354.1 - 9e-21 73.7 2.9 1.8e-10 40.9 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX82354.1 - 2.5e-19 69.4 0.6 3.1e-07 30.8 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX82354.1 - 1e-18 66.9 3.5 7.2e-09 35.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAX82354.1 - 2.1e-17 61.4 1.9 1e-07 31.7 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX82355.1 - 4.2e-61 200.9 19.6 2.2e-07 31.0 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX82355.1 - 6.3e-61 202.0 20.3 2.6e-12 47.0 0.1 9.1 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX82355.1 - 1.3e-59 198.8 29.6 1.6e-13 51.0 1.0 6.1 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX82355.1 - 5.9e-53 176.2 22.9 1e-10 41.6 0.1 6.7 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82355.1 - 1.2e-46 151.3 23.2 0.00012 22.2 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat DUF3447 PF11929.8 EAX82355.1 - 1.5e-08 34.5 1.7 1.5e-08 34.5 1.7 4.6 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX82355.1 - 0.0011 19.1 4.0 9.7 6.4 0.2 5.0 4 2 2 6 6 6 1 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX82355.1 - 0.082 13.2 0.6 7.5 6.9 0.0 3.6 1 1 3 4 4 4 0 Pleckstrin homology domain STAS PF01740.21 EAX82355.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain PRA-PH PF01503.17 EAX82356.1 - 0.42 11.1 3.0 10 6.6 3.5 2.4 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Herpes_IE2_3 PF03361.14 EAX82357.1 - 0.0092 15.9 1.0 0.3 10.9 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX82357.1 - 0.013 15.8 3.8 0.99 9.7 0.8 2.6 2 0 0 2 2 2 0 PPP5 TPR repeat region DUF3839 PF12943.7 EAX82359.1 - 3.3e-157 521.2 14.0 4.2e-157 520.8 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82359.1 - 0.11 12.4 1.2 0.29 11.0 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX82359.1 - 0.14 12.7 5.6 0.15 12.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX82359.1 - 0.16 12.4 2.9 0.14 12.6 0.6 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82359.1 - 0.45 11.0 5.6 5.1 7.6 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX82361.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82361.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX82363.1 - 6.9e-09 35.1 1.6 1.2e-08 34.3 1.1 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX82363.1 - 0.078 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX82363.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor Collagen_bind_2 PF12904.7 EAX82364.1 - 0.077 13.0 0.1 2.6 8.1 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF3839 PF12943.7 EAX82365.1 - 1.2e-156 519.3 13.3 1.6e-156 518.9 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX82365.1 - 0.74 10.2 4.9 13 6.2 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX82365.1 - 4.9 7.7 8.5 1.3 9.6 0.8 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 EAX82366.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX82366.1 - 0.039 13.8 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82366.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX82367.1 - 5.2e-108 360.1 4.8 6.2e-108 359.8 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82367.1 - 0.065 12.7 0.5 0.089 12.3 0.5 1.3 1 1 0 1 1 1 0 Z1 domain DUF4107 PF13389.6 EAX82369.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX82371.1 - 3.2e-34 117.2 0.2 4.2e-34 116.7 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX82371.1 - 0.12 12.3 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon KilA-N PF04383.13 EAX82372.1 - 1.5e-35 121.4 0.8 2.8e-35 120.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82372.1 - 0.0073 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX82372.1 - 0.47 10.9 6.5 4.5 7.8 1.5 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX82373.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82373.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82373.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82373.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) OstA PF03968.14 EAX82376.1 - 0.023 14.9 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 OstA-like protein GPS2_interact PF15784.5 EAX82378.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82378.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1493 PF07377.12 EAX82381.1 - 0.042 14.3 0.6 0.08 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX82381.1 - 0.42 10.7 3.4 9.8 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Trypan_PARP PF05887.11 EAX82382.1 - 0.016 15.2 9.2 0.018 15.0 9.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DOPA_dioxygen PF08883.11 EAX82384.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Dopa 4,5-dioxygenase family 2-oxoacid_dh PF00198.23 EAX82384.1 - 0.19 11.1 3.4 0.61 9.5 0.3 1.9 1 1 1 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF3447 PF11929.8 EAX82385.1 - 4.1e-35 119.6 5.8 4.1e-35 119.6 5.8 3.6 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX82385.1 - 4.4e-29 100.9 9.8 2.4e-17 63.3 1.9 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82385.1 - 4.6e-27 94.0 6.5 1.9e-12 47.4 0.1 6.7 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX82385.1 - 1.1e-22 79.4 2.0 1.7e-06 28.2 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAX82385.1 - 1.5e-21 74.2 4.9 2e-05 24.6 0.0 6.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX82385.1 - 9.5e-16 57.7 5.4 2.4e-07 30.9 0.3 4.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX82385.1 - 0.0051 16.9 1.0 11 6.2 0.1 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3718) ACP53EA PF06313.11 EAX82385.1 - 0.035 14.3 0.5 0.21 11.8 0.2 2.5 2 0 0 2 2 2 0 Drosophila ACP53EA protein Ank_4 PF13637.6 EAX82386.1 - 4.8e-17 62.1 0.3 5.4e-11 42.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX82386.1 - 1.1e-12 48.3 0.5 1.7e-12 47.8 0.5 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX82386.1 - 7e-12 45.2 0.0 2.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX82386.1 - 1.1e-08 34.6 0.1 5.2e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX82386.1 - 1.8e-06 28.1 0.1 0.0044 17.3 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) HEAT_2 PF13646.6 EAX82388.1 - 3.3e-23 81.9 2.0 1.3e-12 47.9 0.2 2.9 1 1 2 3 3 3 3 HEAT repeats PC_rep PF01851.22 EAX82388.1 - 2.3e-15 56.2 15.9 5.4e-10 39.2 0.2 5.5 6 0 0 6 6 6 2 Proteasome/cyclosome repeat DUF1702 PF08012.11 EAX82388.1 - 0.00011 21.2 0.2 0.0022 16.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1702) HEAT_EZ PF13513.6 EAX82388.1 - 0.00036 20.9 3.7 0.3 11.6 0.2 4.1 1 1 3 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EAX82388.1 - 0.002 18.2 0.2 2.5 8.1 0.0 2.4 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX82388.1 - 0.01 16.0 1.2 9 6.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_PBS PF03130.16 EAX82388.1 - 0.038 14.7 6.0 2.4 9.1 0.1 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat IBN_N PF03810.19 EAX82388.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Importin-beta N-terminal domain IL22 PF14565.6 EAX82388.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.6 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor RRM_1 PF00076.22 EAX82389.1 - 2.2e-21 75.4 0.1 4e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX82389.1 - 0.12 12.5 0.4 0.37 10.9 0.0 2.0 2 1 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 EAX82389.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KilA-N PF04383.13 EAX82391.1 - 1.1e-10 41.3 0.4 1.4e-10 41.0 0.1 1.3 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX82391.1 - 0.065 13.3 0.1 0.076 13.0 0.1 1.0 1 0 0 1 1 1 0 Tumour suppressor protein KilA-N PF04383.13 EAX82392.1 - 6.3e-11 42.1 1.0 1.4e-10 41.0 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX82393.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82393.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82393.1 - 4.8e-05 23.2 0.2 0.36 10.5 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82393.1 - 0.00018 21.6 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82393.1 - 0.00063 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82393.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82393.1 - 0.0018 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82393.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82393.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82393.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82393.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82393.1 - 0.51 10.6 4.5 9.3 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) V_cholerae_RfbT PF05575.11 EAX82394.1 - 0.076 12.3 0.0 0.078 12.3 0.0 1.0 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein KilA-N PF04383.13 EAX82395.1 - 1.5e-21 76.4 0.1 2.8e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX82395.1 - 0.067 12.6 0.9 0.091 12.2 0.9 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) His_Phos_2 PF00328.22 EAX82395.1 - 0.33 10.3 2.4 5.9 6.1 0.7 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) DUF3839 PF12943.7 EAX82396.1 - 6.7e-156 516.9 11.8 8.3e-156 516.6 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1444 PF07285.11 EAX82397.1 - 0.035 13.7 0.0 0.039 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Pox_A32 PF04665.12 EAX82398.1 - 3.8e-07 29.8 2.1 5.7e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82398.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82398.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82398.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82398.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX82398.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX82398.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82398.1 - 0.59 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX82399.1 - 3.7e-42 142.7 1.1 6.1e-42 142.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82399.1 - 0.0034 18.0 0.4 0.022 15.4 0.0 2.3 3 0 0 3 3 3 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX82399.1 - 2.2 8.6 6.9 2 8.7 0.3 2.3 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated T5orf172 PF10544.9 EAX82400.1 - 8.2e-06 26.3 0.4 2.6e-05 24.7 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX82400.1 - 0.02 14.7 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX82400.1 - 0.089 12.3 0.2 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain EpuA PF11772.8 EAX82401.1 - 0.026 14.2 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pox_D5 PF03288.16 EAX82403.1 - 0.00016 22.1 2.9 0.0011 19.4 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX82403.1 - 0.0098 15.0 1.0 0.013 14.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX82403.1 - 0.028 15.0 0.1 0.063 13.9 0.1 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82403.1 - 0.08 12.9 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain CHASE3 PF05227.13 EAX82406.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX82406.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) ZoocinA_TRD PF16775.5 EAX82407.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme AAA_22 PF13401.6 EAX82408.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82408.1 - 6.3e-05 22.8 0.3 0.23 11.2 0.0 2.8 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82408.1 - 7.4e-05 22.8 3.1 0.00013 22.0 3.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82408.1 - 0.00038 20.3 0.0 0.00067 19.5 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82408.1 - 0.0011 18.8 1.1 0.0043 16.9 1.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82408.1 - 0.0084 16.4 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82408.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82408.1 - 0.071 13.5 0.1 0.42 11.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX82408.1 - 0.077 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX82408.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX82408.1 - 0.16 12.2 5.2 2.5 8.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX82408.1 - 0.25 11.0 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain GGDEF PF00990.21 EAX82409.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX82409.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX82409.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX82410.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX82411.1 - 3.3e-06 26.9 10.4 0.0047 16.6 0.0 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF4795) Glyco_transf_49 PF13896.6 EAX82411.1 - 0.016 14.6 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan DUF1947 PF09183.10 EAX82411.1 - 0.4 11.0 5.7 4.4 7.7 0.2 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Pox_A32 PF04665.12 EAX82412.1 - 1e-06 28.4 3.4 1e-06 28.4 3.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82412.1 - 3.7e-05 24.0 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82412.1 - 4.5e-05 23.2 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82412.1 - 9.3e-05 22.5 3.0 0.00023 21.2 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82412.1 - 0.00043 20.1 0.1 0.00081 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82412.1 - 0.00089 19.1 0.4 0.0015 18.4 0.4 1.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82412.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82412.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82412.1 - 0.073 12.6 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX82412.1 - 0.091 12.5 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX82412.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82412.1 - 0.093 13.2 0.1 0.77 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82412.1 - 0.37 11.1 3.8 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82413.1 - 2.3e-45 153.0 0.7 4.2e-45 152.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82413.1 - 0.031 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Gly-zipper_Omp PF13488.6 EAX82414.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX82414.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX82414.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX82414.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82414.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif KilA-N PF04383.13 EAX82415.1 - 1.4e-23 82.9 0.1 1.6e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain KilA-N PF04383.13 EAX82416.1 - 2.4e-33 114.3 0.2 2.4e-33 114.3 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82416.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX82416.1 - 0.63 10.5 6.9 4.9 7.7 1.7 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX82417.1 - 3.9e-07 29.8 2.8 3.9e-07 29.8 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82417.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82417.1 - 6.3e-05 22.8 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82417.1 - 0.00016 21.7 3.4 0.00036 20.6 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82417.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82417.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82417.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82417.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82417.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82417.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82417.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82417.1 - 0.39 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Phage_fiber PF03335.13 EAX82419.1 - 9.2 6.8 8.1 21 5.6 1.8 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF2400 PF09674.10 EAX82421.1 - 0.03 14.3 0.5 0.044 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX82421.1 - 0.033 14.2 0.3 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX82421.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX82422.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX82422.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX82423.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta 40S_S4_C PF16121.5 EAX82424.1 - 2.7e-10 39.7 0.0 4.4 7.0 0.0 9.3 10 0 0 10 10 10 10 40S ribosomal protein S4 C-terminus HSP70 PF00012.20 EAX82425.1 - 8.2e-136 453.6 0.1 9.2e-136 453.5 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX82425.1 - 5.9e-12 45.0 0.0 3.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 EAX82425.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 EAX82425.1 - 0.022 14.0 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EAX82425.1 - 0.26 11.7 0.9 1.4 9.3 0.1 2.5 2 2 0 2 2 2 0 Cell division protein FtsA Glutaminase PF04960.15 EAX82426.1 - 2.8e-91 305.7 0.3 3.1e-91 305.5 0.3 1.0 1 0 0 1 1 1 1 Glutaminase Thymidylate_kin PF02223.17 EAX82427.1 - 2.6e-44 151.1 0.0 3.1e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EAX82427.1 - 1.4e-05 25.4 0.0 1.8e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAX82427.1 - 0.00044 20.8 0.1 0.0018 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX82427.1 - 0.0072 16.6 0.0 0.025 14.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EAX82427.1 - 0.0087 16.1 0.9 0.38 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EAX82427.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 EAX82427.1 - 0.022 15.2 0.0 0.09 13.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EAX82427.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EAX82427.1 - 0.037 14.6 0.1 0.069 13.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EAX82427.1 - 0.054 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 EAX82427.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EAX82427.1 - 0.07 13.5 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAX82427.1 - 0.16 11.8 0.0 0.58 10.1 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase CAMSAP_CH PF11971.8 EAX82428.1 - 1.8e-07 30.9 1.0 4.1e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 EAX82428.1 - 0.0044 17.1 0.1 0.011 15.8 0.1 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 EAX82428.1 - 0.021 15.0 0.2 0.021 15.0 0.2 3.4 3 0 0 3 3 3 0 Calponin homology (CH) domain DUF1075 PF06388.11 EAX82428.1 - 0.8 9.8 0.0 0.8 9.8 0.0 4.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1075) Pox_A32 PF04665.12 EAX82429.1 - 7.2e-05 22.4 3.6 0.00014 21.4 3.6 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX82429.1 - 0.014 15.4 0.4 0.039 14.0 0.1 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX82429.1 - 0.016 14.8 0.2 0.031 13.9 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3839 PF12943.7 EAX82430.1 - 2e-156 518.6 12.0 2.5e-156 518.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82430.1 - 0.13 12.8 5.5 2.1 8.9 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82430.1 - 5.5 7.4 7.9 9.2 6.7 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal DUF4108 PF13390.6 EAX82434.1 - 1.3e-62 209.9 5.9 1.5e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX82435.1 - 8.4e-156 516.6 14.7 9.8e-156 516.3 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX82435.1 - 0.12 11.9 0.1 0.52 9.8 0.1 1.9 1 1 1 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX82435.1 - 0.16 11.8 1.1 0.63 9.9 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82435.1 - 0.33 11.4 6.5 1.5 9.3 0.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX82435.1 - 0.39 11.0 2.4 1.8 8.9 0.0 2.9 2 2 1 3 3 3 0 Rx N-terminal domain PTR PF12789.7 EAX82436.1 - 3.5e-09 36.6 9.2 3.8e-08 33.3 5.0 4.2 5 0 0 5 5 5 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX82436.1 - 0.053 13.7 0.0 5.8 7.2 0.1 2.4 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX82436.1 - 0.97 9.4 3.6 18 5.3 0.1 2.9 2 1 1 3 3 3 0 Interleukin 2 DUF3839 PF12943.7 EAX82437.1 - 9.4e-149 493.5 12.6 1.3e-148 493.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX82437.1 - 0.0049 17.4 0.3 0.095 13.2 0.2 3.0 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX82437.1 - 0.017 15.5 0.9 0.05 14.0 0.1 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82437.1 - 1.1 9.8 5.6 2.9 8.4 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX82438.1 - 2.5e-05 24.3 0.4 2.5e-05 24.3 0.4 4.2 5 0 0 5 5 5 1 Phage tail repeat like DUF3417 PF11897.8 EAX82438.1 - 0.026 15.0 0.6 0.2 12.1 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX82438.1 - 0.03 14.1 7.3 0.055 13.3 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX82438.1 - 0.055 13.2 0.1 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4116 PF13475.6 EAX82438.1 - 0.057 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX82438.1 - 0.5 9.9 14.1 0.089 12.4 6.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX82439.1 - 0.018 15.5 0.8 0.036 14.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX82440.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX82441.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX82442.1 - 3.4e-22 79.3 1.2 3.7e-22 79.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF45 PF01863.17 EAX82443.1 - 0.039 14.0 2.2 0.043 13.9 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 Trypan_PARP PF05887.11 EAX82444.1 - 0.025 14.6 9.1 0.034 14.1 9.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2960 PF11173.8 EAX82445.1 - 0.033 14.6 0.3 0.069 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) GPS2_interact PF15784.5 EAX82446.1 - 0.077 13.4 1.5 0.12 12.9 1.5 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82446.1 - 0.099 11.6 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX82447.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Amidase02_C PF12123.8 EAX82448.1 - 0.026 14.2 0.0 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX82450.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82450.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82450.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82450.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82450.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82450.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82450.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82450.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82450.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82450.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82450.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82450.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82451.1 - 3.6e-40 136.3 0.6 9e-40 135.0 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82451.1 - 0.002 18.7 0.7 0.014 16.0 0.0 2.3 3 0 0 3 3 3 1 Parathyroid hormone family zf-RING_9 PF13901.6 EAX82451.1 - 0.14 12.1 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon T5orf172 PF10544.9 EAX82452.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX82453.1 - 1.2e-133 444.0 13.4 3.7e-133 442.4 13.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82453.1 - 0.04 14.4 6.4 3.6 8.1 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX82453.1 - 0.061 13.8 1.7 0.15 12.5 0.3 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX82453.1 - 0.083 13.3 0.5 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX82453.1 - 2.4 8.5 8.4 6.5 7.1 0.3 4.0 3 2 2 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX82454.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82454.1 - 0.013 15.3 0.9 0.045 13.6 0.9 1.9 1 1 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX82454.1 - 0.16 11.4 0.8 0.36 10.3 0.3 1.7 2 0 0 2 2 2 0 Legume lectin domain GPS2_interact PF15784.5 EAX82455.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82455.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX82456.1 - 4.7e-41 139.1 0.4 1.2e-40 137.8 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3552 PF12072.8 EAX82456.1 - 0.019 14.4 6.7 0.038 13.4 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DNA_pol_B_2 PF03175.13 EAX82457.1 - 4.6e-24 85.1 9.3 5.3e-23 81.6 8.4 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX82457.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4107 PF13389.6 EAX82458.1 - 5.2e-72 241.3 4.1 7.9e-72 240.7 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82458.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX82459.1 - 4.9e-07 29.6 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX82460.1 - 2.1e-136 453.0 11.3 2.4e-136 452.9 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82460.1 - 0.05 14.0 3.3 0.1 13.0 0.7 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82460.1 - 0.4 11.2 7.1 3.9 8.0 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX82462.1 - 0.044 13.8 7.8 0.062 13.3 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX82463.1 - 0.047 14.1 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PTR PF12789.7 EAX82464.1 - 1.8e-14 53.6 26.9 8.5e-09 35.3 4.5 5.4 5 0 0 5 5 5 3 Phage tail repeat like Cas_Csm6 PF09659.10 EAX82464.1 - 0.00017 20.5 6.2 0.067 12.0 2.7 2.3 1 1 1 2 2 2 2 CRISPR-associated protein (Cas_Csm6) RecG_N PF17190.4 EAX82464.1 - 2.1 9.1 9.5 32 5.3 0.0 4.3 5 0 0 5 5 5 0 RecG N-terminal helical domain RPA_C PF08784.11 EAX82465.1 - 0.0075 16.9 0.0 0.014 16.1 0.0 1.5 1 1 0 1 1 1 1 Replication protein A C terminal RMI2 PF16100.5 EAX82465.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 EAX82465.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain BOF PF04076.13 EAX82465.1 - 0.072 13.1 0.3 0.25 11.4 0.3 1.8 1 1 1 2 2 2 0 Bacterial OB fold (BOF) protein GPS2_interact PF15784.5 EAX82466.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82466.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX82467.1 - 0.042 13.8 9.8 0.057 13.4 9.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX82468.1 - 5.2e-54 182.1 7.3 5.7e-54 181.9 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX82468.1 - 0.03 14.5 0.1 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX82469.1 - 6.1e-06 26.6 1.7 3.3e-05 24.3 1.7 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82469.1 - 0.0063 17.1 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82469.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Myb_DNA-binding PF00249.31 EAX82470.1 - 6.2e-21 74.3 3.6 3.8e-10 39.8 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82470.1 - 4.9e-20 71.5 11.9 2.3e-12 47.0 4.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX82470.1 - 0.017 15.3 4.4 0.1 12.8 0.6 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Atg29_N PF18388.1 EAX82470.1 - 0.054 13.3 0.3 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Atg29 N-terminal domain Ndr PF03096.14 EAX82470.1 - 0.18 10.5 1.2 0.24 10.0 1.2 1.4 1 0 0 1 1 1 0 Ndr family Myb_DNA-bind_7 PF15963.5 EAX82470.1 - 0.95 9.4 10.0 0.09 12.7 1.3 2.4 2 1 0 2 2 2 0 Myb DNA-binding like GPS2_interact PF15784.5 EAX82471.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82471.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX82472.1 - 1.3e-156 519.2 13.7 1.6e-156 519.0 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82472.1 - 0.019 15.4 0.8 0.1 13.1 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82472.1 - 0.043 14.3 4.2 1.9 9.0 0.1 3.4 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase P4Ha_N PF08336.11 EAX82472.1 - 0.054 13.5 1.8 4.5 7.3 0.0 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2408 PF10303.9 EAX82472.1 - 1.4 9.4 4.0 1.2 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Terminase_2 PF03592.16 EAX82472.1 - 4.2 7.8 8.0 2.9 8.3 3.0 2.6 1 1 1 2 2 2 0 Terminase small subunit KilA-N PF04383.13 EAX82473.1 - 1.6e-21 76.3 0.3 4.3e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Tubulin_C PF03953.17 EAX82474.1 - 6.8e-40 136.1 0.0 9.2e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain PRKCSH PF07915.13 EAX82475.1 - 9.7e-07 29.7 0.6 6.3e-06 27.1 0.3 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EAX82475.1 - 0.00049 19.8 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 EAX82475.1 - 0.01 15.9 0.2 0.049 13.7 0.0 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 EAX82475.1 - 0.03 14.2 0.2 0.049 13.5 0.1 1.4 1 1 0 1 1 1 0 Autophagy-related protein 27 Ribosomal_L14 PF00238.19 EAX82476.1 - 7e-34 116.5 0.6 8.4e-34 116.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF1722 PF08349.11 EAX82477.1 - 0.035 14.4 0.4 5 7.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) HlyD_D23 PF16576.5 EAX82477.1 - 0.074 12.3 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3839 PF12943.7 EAX82478.1 - 3.2e-114 380.4 8.5 3.6e-114 380.2 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82478.1 - 0.72 10.3 3.8 0.79 10.2 1.0 2.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX82479.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX82481.1 - 2.3e-73 245.7 4.4 2.8e-73 245.4 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX82481.1 - 0.17 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX82482.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF806 PF05657.11 EAX82483.1 - 0.037 14.5 0.4 0.083 13.4 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF806) Skp1 PF01466.19 EAX82483.1 - 0.25 11.5 1.6 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Skp1 family, dimerisation domain PaRep2a PF07903.11 EAX82484.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82484.1 - 6.7 6.7 11.8 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family KilA-N PF04383.13 EAX82486.1 - 3e-18 65.7 1.8 3.3e-18 65.6 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82486.1 - 0.0039 17.8 0.0 0.0094 16.6 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX82487.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82487.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82487.1 - 4.9e-05 23.1 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82487.1 - 0.00014 21.9 3.1 0.00035 20.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82487.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82487.1 - 0.0012 18.6 0.6 0.0023 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82487.1 - 0.0018 18.0 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82487.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82487.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82487.1 - 0.087 13.2 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82487.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82487.1 - 0.39 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX82489.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX82490.1 - 5.1e-05 23.7 2.3 0.00031 21.2 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82490.1 - 0.023 15.3 0.1 0.044 14.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82490.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Imm70 PF15601.6 EAX82491.1 - 1.4 8.5 63.1 12 5.5 0.1 15.4 1 1 23 24 24 24 0 Immunity protein 70 PTR PF12789.7 EAX82492.1 - 3.8e-64 212.6 47.4 8.3e-34 115.5 16.7 4.9 3 1 2 5 5 5 4 Phage tail repeat like Apolipoprotein PF01442.18 EAX82492.1 - 0.22 11.4 1.0 0.32 10.8 1.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PH_TFIIH PF08567.11 EAX82492.1 - 2 8.8 8.0 44 4.5 0.1 4.5 2 1 4 6 6 6 0 TFIIH p62 subunit, N-terminal domain PTR PF12789.7 EAX82493.1 - 3.1e-12 46.3 30.8 2.8e-08 33.7 4.8 5.2 5 0 0 5 5 5 3 Phage tail repeat like RecG_N PF17190.4 EAX82493.1 - 0.054 14.2 2.5 27 5.6 0.0 3.9 3 0 0 3 3 3 0 RecG N-terminal helical domain UPF0242 PF06785.11 EAX82493.1 - 1 9.4 6.2 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3839 PF12943.7 EAX82494.1 - 2.5e-154 511.7 12.3 2.8e-154 511.5 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82494.1 - 1.4 9.4 6.9 3.6 8.1 0.2 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82496.1 - 6.7e-151 500.5 14.6 7.6e-151 500.3 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82496.1 - 0.098 12.5 1.3 0.35 10.7 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82496.1 - 0.43 11.1 9.0 0.59 10.6 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82496.1 - 1.3 9.4 7.4 3.1 8.2 0.7 3.6 3 2 2 5 5 5 0 Tup N-terminal Rx_N PF18052.1 EAX82496.1 - 1.3 9.4 4.2 1.6 9.1 0.2 2.9 2 2 1 3 3 3 0 Rx N-terminal domain KilA-N PF04383.13 EAX82497.1 - 1.8e-34 118.0 0.1 2.3e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX82497.1 - 0.022 14.8 0.3 0.026 14.5 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF4107 PF13389.6 EAX82498.1 - 8.3e-63 211.4 2.4 1.1e-62 211.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82498.1 - 0.11 12.8 0.5 0.16 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF2939 PF11159.8 EAX82500.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX82500.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX82500.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX82500.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX82501.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_D5 PF03288.16 EAX82502.1 - 1.9e-05 25.1 3.0 0.00013 22.4 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82502.1 - 0.04 14.5 0.1 0.073 13.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82502.1 - 0.078 13.0 0.3 0.15 12.1 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX82503.1 - 2.3e-57 192.9 4.2 2.5e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX82504.1 - 0.12 12.6 4.3 0.15 12.3 4.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX82504.1 - 6.8 6.7 8.0 16 5.5 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T5orf172 PF10544.9 EAX82505.1 - 2.1e-06 28.2 0.2 5.7e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82505.1 - 0.027 14.3 0.2 0.096 12.5 0.1 1.9 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX82505.1 - 0.18 11.3 0.7 2.3 7.7 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX82506.1 - 2.8e-66 223.4 5.2 3.6e-66 223.1 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX82506.1 - 0.013 15.5 0.7 2.8 8.0 0.0 2.3 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MSA-2c PF12238.8 EAX82507.1 - 0.00036 20.6 1.7 0.0005 20.1 1.7 1.3 1 1 0 1 1 1 1 Merozoite surface antigen 2c CCDC53 PF10152.9 EAX82507.1 - 0.0082 16.6 0.2 0.57 10.6 0.0 2.2 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex MitMem_reg PF13012.6 EAX82507.1 - 0.012 16.0 0.5 0.026 14.9 0.5 1.9 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Phage_pRha PF09669.10 EAX82507.1 - 0.032 14.8 3.3 0.94 10.1 0.6 2.6 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF4200 PF13863.6 EAX82507.1 - 0.034 14.5 2.6 0.034 14.5 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin_2 PF14523.6 EAX82507.1 - 0.043 14.2 4.5 0.054 13.9 1.5 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF3584 PF12128.8 EAX82507.1 - 0.052 11.1 2.2 0.068 10.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSBP1 PF06825.12 EAX82507.1 - 0.053 13.4 0.4 0.36 10.7 0.3 2.4 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Herpes_UL4 PF03277.13 EAX82507.1 - 0.097 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF1664 PF07889.12 EAX82507.1 - 0.21 11.6 2.6 0.15 12.1 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 EAX82507.1 - 0.42 10.7 4.5 1.4 9.0 1.8 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.9 EAX82507.1 - 1.3 9.1 5.1 0.86 9.6 0.5 2.7 2 2 1 3 3 3 0 Short coiled-coil protein Meiosis_expr PF15163.6 EAX82508.1 - 0.019 15.6 0.9 0.026 15.2 0.3 1.5 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX82508.1 - 0.83 9.6 11.0 0.12 12.3 2.8 3.2 4 1 0 4 4 4 0 Spo12 family TPR_MLP1_2 PF07926.12 EAX82509.1 - 0.012 15.7 0.8 0.015 15.4 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX82509.1 - 0.44 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX82510.1 - 1.4e-157 522.4 14.6 1.7e-157 522.1 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82510.1 - 0.076 12.9 1.3 0.22 11.4 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX82510.1 - 0.13 12.7 0.3 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX82510.1 - 0.83 10.1 5.4 5 7.6 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82511.1 - 3.9e-05 24.1 0.1 8.8e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX82513.1 - 2.6e-68 229.3 2.8 3.4e-68 228.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82513.1 - 0.12 12.8 0.6 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta GPS2_interact PF15784.5 EAX82515.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82515.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX82518.1 - 2.4e-68 230.2 4.5 3.1e-68 229.8 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX82519.1 - 1.8e-07 31.6 0.1 2.5e-06 28.0 0.1 2.4 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX82520.1 - 1.3e-32 112.0 1.5 1.5e-32 111.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX82522.1 - 2.8e-149 495.2 16.8 3.4e-149 494.9 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82522.1 - 0.36 11.4 4.8 1.7 9.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82522.1 - 1 9.9 6.3 1.8 9.1 1.0 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82523.1 - 6.9e-25 87.9 4.2 9.9e-25 87.4 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX82523.1 - 0.048 14.0 0.6 0.26 11.6 0.0 2.1 1 1 1 2 2 2 0 PRD domain KilA-N PF04383.13 EAX82524.1 - 4.3e-41 139.3 1.2 6e-41 138.8 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82524.1 - 0.0073 16.9 0.2 0.024 15.3 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX82525.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82525.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82525.1 - 7.3e-05 22.6 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82525.1 - 0.00011 22.2 2.6 0.00024 21.2 2.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82525.1 - 0.00064 19.5 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82525.1 - 0.0014 18.5 0.7 0.0026 17.6 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82525.1 - 0.0017 18.0 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82525.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82525.1 - 0.075 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82525.1 - 0.089 13.2 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82525.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82525.1 - 0.18 12.1 3.1 8.8 6.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX82525.1 - 0.69 10.1 8.4 8.1 6.7 0.1 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) GPS2_interact PF15784.5 EAX82526.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82526.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Gly-zipper_Omp PF13488.6 EAX82528.1 - 0.0045 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX82528.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82528.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif bZIP_1 PF00170.21 EAX82530.1 - 0.0083 16.2 0.1 0.036 14.1 0.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF4108 PF13390.6 EAX82531.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RNA_polI_A34 PF08208.11 EAX82532.1 - 0.93 9.6 15.6 0.95 9.5 15.6 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2897 PF11446.8 EAX82532.1 - 4 7.4 6.9 8.3 6.4 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) Transposase_mut PF00872.18 EAX82533.1 - 0.0026 16.7 0.7 0.0034 16.3 0.4 1.4 1 1 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX82533.1 - 0.021 14.8 0.3 0.029 14.3 0.3 1.2 1 0 0 1 1 1 0 Vta1 like DUF4107 PF13389.6 EAX82535.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX82535.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX82536.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF2897 PF11446.8 EAX82537.1 - 0.65 9.9 4.1 1.2 9.1 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX82538.1 - 7e-62 207.6 6.2 7.8e-62 207.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX82540.1 - 6.5e-103 337.5 75.2 9.8e-16 58.1 1.5 8.1 2 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX82540.1 - 1.2e-72 237.4 15.7 1.1e-06 28.8 0.0 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.6 EAX82540.1 - 6.6e-70 230.6 18.3 3.4e-10 40.2 0.0 12.2 6 2 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82540.1 - 7.4e-59 188.8 29.9 9.3e-06 25.6 0.0 14.9 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 EAX82540.1 - 8.4e-53 175.8 16.5 6.1e-11 42.3 0.0 10.0 5 2 7 12 12 12 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX82540.1 - 3.3e-35 119.9 10.0 3.3e-35 119.9 10.0 5.7 4 2 1 5 5 5 2 Domain of unknown function (DUF3447) RL PF17797.1 EAX82540.1 - 0.4 10.7 8.5 4.2 7.4 1.2 4.9 5 0 0 5 5 5 0 RL domain RNase_PH_C PF03725.15 EAX82540.1 - 0.78 9.8 3.6 1e+02 3.0 0.0 4.6 4 1 2 6 6 6 0 3' exoribonuclease family, domain 2 MCC-bdg_PDZ PF10506.9 EAX82540.1 - 2.6 8.1 5.2 31 4.7 0.1 4.4 5 0 0 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ribosomal_L27e PF01777.18 EAX82541.1 - 2.2e-21 76.0 6.8 2.8e-21 75.6 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAX82541.1 - 0.0062 16.4 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAX82541.1 - 0.16 11.4 0.1 0.18 11.2 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PQ-loop PF04193.14 EAX82542.1 - 5.4e-10 38.9 1.8 5.4e-10 38.9 1.8 2.8 2 1 1 3 3 3 1 PQ loop repeat DUF805 PF05656.14 EAX82542.1 - 0.27 11.7 3.4 0.77 10.2 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) KilA-N PF04383.13 EAX82543.1 - 4.2e-40 136.1 1.0 6.3e-40 135.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82543.1 - 0.017 15.7 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX82544.1 - 1e-06 29.2 0.1 2.5e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82544.1 - 0.0045 16.8 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX82544.1 - 0.14 11.7 0.4 0.41 10.1 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain T5orf172 PF10544.9 EAX82545.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4108 PF13390.6 EAX82547.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Roc PF08477.13 EAX82548.1 - 8.1e-30 103.5 0.0 9.4e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX82548.1 - 9.2e-30 103.4 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EAX82548.1 - 2.4e-08 33.6 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX82548.1 - 5e-07 29.3 0.0 2.9e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX82548.1 - 8.8e-05 22.6 0.0 0.0001 22.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX82548.1 - 0.0017 17.8 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX82548.1 - 0.0063 16.4 0.3 0.06 13.2 0.1 2.2 1 1 2 3 3 3 1 RsgA GTPase cobW PF02492.19 EAX82548.1 - 0.012 15.2 0.0 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EAX82548.1 - 0.016 14.9 0.0 0.044 13.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAX82548.1 - 0.025 14.3 0.2 0.036 13.8 0.2 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX82548.1 - 0.029 14.8 0.0 0.037 14.4 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EAX82548.1 - 0.036 14.1 0.0 0.05 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX82548.1 - 0.038 14.3 0.0 0.045 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX82548.1 - 0.049 13.1 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EAX82548.1 - 0.084 12.9 0.0 0.097 12.7 0.0 1.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EAX82548.1 - 0.087 11.7 0.1 3.1 6.6 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PTR PF12789.7 EAX82549.1 - 5.9e-11 42.3 3.7 1.1e-08 35.0 0.4 4.3 5 0 0 5 5 5 2 Phage tail repeat like YmaF PF12788.7 EAX82549.1 - 0.19 12.3 8.0 31 5.2 0.1 4.2 4 1 0 4 4 4 0 YmaF family DUF4795 PF16043.5 EAX82549.1 - 0.45 10.1 10.9 0.15 11.7 2.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX82549.1 - 8.7 6.8 24.5 4.7 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat T5orf172 PF10544.9 EAX82550.1 - 4.2e-07 30.4 0.3 8.5e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82552.1 - 6.3e-31 106.5 0.3 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX82553.1 - 1.1e-156 519.4 13.1 1.4e-156 519.1 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82553.1 - 0.1 12.9 0.5 2 8.8 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82553.1 - 0.2 12.1 6.3 0.85 10.1 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX82553.1 - 1.6 9.4 4.8 6 7.6 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF2408 PF10303.9 EAX82553.1 - 2.3 8.8 4.8 1.2 9.8 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX82554.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX82555.1 - 1.2e-06 29.0 0.2 2.4e-06 28.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82557.1 - 9.8e-40 134.9 0.3 2.2e-39 133.8 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX82557.1 - 0.091 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase VirK PF06903.12 EAX82558.1 - 0.029 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 VirK protein Gcd10p PF04189.13 EAX82558.1 - 0.68 9.0 3.4 0.99 8.5 1.7 2.0 1 1 1 2 2 2 0 Gcd10p family T5orf172 PF10544.9 EAX82559.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX82560.1 - 5.4e-155 513.9 11.8 6.9e-155 513.6 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82560.1 - 0.14 12.6 2.3 0.7 10.4 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82560.1 - 0.43 11.1 4.7 0.2 12.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX82561.1 - 5.8e-43 145.3 0.7 1e-42 144.5 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82561.1 - 0.0097 16.5 0.4 0.03 15.0 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family DUF3839 PF12943.7 EAX82562.1 - 6.5e-40 137.1 3.8 9.4e-40 136.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX82562.1 - 0.064 12.4 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DNA_pol_B_2 PF03175.13 EAX82563.1 - 1.6e-09 37.2 0.8 3e-09 36.3 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAX82568.1 - 3.9e-07 30.5 0.3 7.8e-07 29.6 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX82568.1 - 0.12 13.0 0.4 0.3 11.8 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX82569.1 - 2.1e-35 120.9 0.7 2.1e-35 120.9 0.7 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82569.1 - 0.0051 17.4 0.1 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX82569.1 - 0.99 9.4 4.6 2.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX82570.1 - 1.1e-06 28.3 4.7 1.1e-06 28.3 3.0 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82570.1 - 3.4e-05 23.7 0.2 0.34 10.6 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82570.1 - 4.5e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82570.1 - 0.00029 20.9 4.3 0.00051 20.1 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82570.1 - 0.00076 19.3 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82570.1 - 0.0016 18.3 0.9 0.0029 17.5 0.5 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82570.1 - 0.0048 16.6 2.5 0.015 15.0 0.4 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82570.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX82570.1 - 0.081 13.0 0.6 1.2 9.2 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX82570.1 - 0.09 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX82570.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82570.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82570.1 - 0.27 11.5 4.5 4.3 7.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX82570.1 - 0.97 10.1 11.8 0.43 11.3 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Clathrin PF00637.20 EAX82571.1 - 0.011 15.7 1.7 0.022 14.6 0.1 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Med14 PF08638.11 EAX82571.1 - 0.023 14.1 0.0 0.07 12.5 0.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit MED14 CNH PF00780.22 EAX82571.1 - 0.049 13.2 0.2 0.22 11.1 0.2 2.1 1 1 0 1 1 1 0 CNH domain Spc7 PF08317.11 EAX82572.1 - 0.00056 18.9 19.5 0.0006 18.8 19.0 1.2 1 1 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 EAX82572.1 - 0.00074 19.8 15.6 0.0012 19.2 15.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EAX82572.1 - 0.0015 18.4 15.6 0.0076 16.1 15.6 1.9 1 1 0 1 1 1 1 Phage minor structural protein GP20 V_ATPase_I PF01496.19 EAX82572.1 - 0.0023 16.0 5.1 0.0023 15.9 5.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ADIP PF11559.8 EAX82572.1 - 0.0055 16.8 9.5 0.0055 16.8 9.5 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.13 EAX82572.1 - 0.014 15.9 4.0 0.014 15.9 4.0 3.7 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3130 PF11328.8 EAX82572.1 - 0.029 14.6 2.5 4.9 7.5 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 THP2 PF09432.10 EAX82572.1 - 0.042 13.9 7.3 0.095 12.7 7.3 1.5 1 1 0 1 1 1 0 Tho complex subunit THP2 TMF_DNA_bd PF12329.8 EAX82572.1 - 0.042 13.8 11.0 0.042 13.8 11.0 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2009 PF09418.10 EAX82572.1 - 0.055 12.5 8.0 0.065 12.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) SKA1 PF07160.12 EAX82572.1 - 0.075 12.9 16.7 0.085 12.7 6.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Prefoldin_2 PF01920.20 EAX82572.1 - 0.081 12.9 18.6 0.42 10.6 2.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit ZapB PF06005.12 EAX82572.1 - 0.11 13.0 21.3 0.23 11.9 7.6 2.4 2 1 0 2 2 2 0 Cell division protein ZapB FapA PF03961.13 EAX82572.1 - 0.13 10.8 12.0 0.15 10.7 12.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EAX82572.1 - 0.14 11.9 15.3 0.37 10.6 4.7 2.5 2 0 0 2 2 2 0 Septum formation initiator TSNAXIP1_N PF15739.5 EAX82572.1 - 0.18 12.2 14.1 0.45 10.9 4.5 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus RBD-FIP PF09457.10 EAX82572.1 - 0.19 11.7 0.4 0.19 11.7 0.4 3.6 4 0 0 4 4 3 0 FIP domain CENP-F_leu_zip PF10473.9 EAX82572.1 - 0.2 11.7 24.4 1.1 9.3 4.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EAX82572.1 - 0.24 11.4 10.5 1.1 9.3 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EAX82572.1 - 0.28 10.4 10.3 0.35 10.1 10.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 EAX82572.1 - 0.28 11.7 17.1 0.13 12.8 6.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 EAX82572.1 - 0.3 11.1 19.1 1.5 8.9 2.2 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_TATA_bd PF12325.8 EAX82572.1 - 0.54 10.5 18.3 0.81 9.9 16.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EAX82572.1 - 0.59 10.2 23.0 0.6 10.2 9.9 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4363 PF14276.6 EAX82572.1 - 0.63 10.2 11.6 0.15 12.2 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) YabA PF06156.13 EAX82572.1 - 0.65 10.7 17.2 2.6 8.7 2.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Phlebovirus_NSM PF07246.11 EAX82572.1 - 0.69 9.2 9.1 3.5 6.9 9.1 1.9 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Peptidase_M41 PF01434.18 EAX82572.1 - 1 9.2 7.4 0.62 9.9 4.4 2.0 1 1 1 2 2 2 0 Peptidase family M41 Jnk-SapK_ap_N PF09744.9 EAX82572.1 - 1.1 9.5 19.3 1.7 8.9 19.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Baculo_p24 PF05073.12 EAX82572.1 - 1.1 9.0 9.3 7.2 6.4 9.3 2.2 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF724 PF05266.14 EAX82572.1 - 1.1 9.0 16.1 0.043 13.6 6.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 EAX82572.1 - 1.2 8.4 11.4 2.9 7.2 11.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EAX82572.1 - 1.5 8.9 26.4 4.5 7.3 21.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 EAX82572.1 - 1.6 7.6 11.3 1.8 7.4 11.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Allexi_40kDa PF05549.11 EAX82572.1 - 1.7 8.1 13.1 4.1 6.8 4.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein vATP-synt_E PF01991.18 EAX82572.1 - 1.8 7.9 19.2 2.1 7.7 6.5 2.3 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit IL31 PF15209.6 EAX82572.1 - 2.3 8.0 11.2 3.1 7.6 1.8 2.5 1 1 1 2 2 2 0 Interleukin 31 APG6_N PF17675.1 EAX82572.1 - 2.3 8.7 24.3 40 4.7 22.7 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Peptidase_C98 PF15499.6 EAX82572.1 - 2.4 7.6 9.2 13 5.1 9.2 1.9 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ax_dynein_light PF10211.9 EAX82572.1 - 2.7 7.9 18.8 1.2 9.0 3.4 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain Dzip-like_N PF13815.6 EAX82572.1 - 2.7 8.0 14.8 0.73 9.8 4.8 2.4 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C4H2 PF10146.9 EAX82572.1 - 2.7 8.2 13.5 4.1 7.7 13.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.14 EAX82572.1 - 3.5 8.0 20.1 5.8 7.3 20.1 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tho2 PF11262.8 EAX82572.1 - 3.8 6.6 16.9 0.57 9.3 7.5 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 FlaC_arch PF05377.11 EAX82572.1 - 4.6 7.7 12.5 15 6.1 5.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.6 EAX82572.1 - 4.6 7.4 22.5 1.2e+02 2.8 22.5 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 EAX82572.1 - 6.4 5.8 20.5 14 4.7 20.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 EAX82572.1 - 7.3 7.0 22.0 1e+02 3.3 22.0 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region BRE1 PF08647.11 EAX82572.1 - 7.7 6.7 25.5 0.25 11.5 12.3 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 EAX82572.1 - 9.5 6.5 9.4 2.2 8.6 5.2 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Tho2 PF11262.8 EAX82573.1 - 0.084 12.1 3.0 0.093 11.9 3.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PEPcase PF00311.17 EAX82573.1 - 0.11 10.6 0.5 0.12 10.5 0.5 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Spo12 PF05032.12 EAX82573.1 - 7.2 6.6 12.1 0.21 11.5 2.9 2.6 4 0 0 4 4 4 0 Spo12 family DUF4107 PF13389.6 EAX82575.1 - 1.3e-72 243.2 3.7 1.7e-72 242.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX82577.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX82578.1 - 1.2e-72 243.3 4.8 1.4e-72 243.1 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX82579.1 - 0.006 16.2 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase TPR_MLP1_2 PF07926.12 EAX82580.1 - 0.007 16.4 0.4 0.0096 16.0 0.4 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX82580.1 - 0.015 14.5 2.1 0.016 14.4 2.1 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX82580.1 - 0.051 13.4 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Pox_D5 PF03288.16 EAX82581.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82581.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82581.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX82582.1 - 4.4e-64 214.7 6.2 4.9e-64 214.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX82583.1 - 1.9 8.8 5.1 1.9 8.8 3.8 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region AAA_11 PF13086.6 EAX82584.1 - 0.0067 16.3 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX82584.1 - 0.017 15.4 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82584.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 EAX82584.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX82584.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain FAR1 PF03101.15 EAX82586.1 - 0.02 15.6 0.1 0.04 14.6 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain GPS2_interact PF15784.5 EAX82587.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82587.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX82588.1 - 0.073 13.0 6.7 0.094 12.7 6.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82588.1 - 1.9 8.9 5.1 2.4 8.6 5.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX82589.1 - 0.021 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PSP PF04046.16 EAX82591.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Thioredoxin PF00085.20 EAX82592.1 - 6.5e-14 51.8 0.0 7.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAX82592.1 - 0.0055 16.9 0.1 0.0062 16.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 EAX82592.1 - 0.027 13.4 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin Ank_2 PF12796.7 EAX82593.1 - 3.7e-19 69.1 2.8 1.3e-14 54.5 0.4 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82593.1 - 1e-15 57.9 0.5 5.1e-10 39.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX82593.1 - 8.7e-13 48.2 0.1 0.00056 20.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82593.1 - 1.3e-10 40.6 0.4 0.21 12.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAX82593.1 - 5.8e-07 29.7 0.3 0.15 12.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat hDGE_amylase PF14701.6 EAX82593.1 - 0.0062 15.7 0.2 0.0089 15.2 0.2 1.3 1 1 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF2812 PF11193.8 EAX82593.1 - 0.092 13.0 0.1 0.63 10.3 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2812) DUF3839 PF12943.7 EAX82594.1 - 1.1e-156 519.4 13.1 1.4e-156 519.1 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82594.1 - 3.9 8.0 8.0 1.9 9.0 0.7 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX82595.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX82596.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX82597.1 - 0.029 14.8 0.9 0.059 13.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX82598.1 - 3e-05 24.0 0.6 3e-05 24.0 0.6 4.4 4 1 1 5 5 5 1 Phage tail repeat like EDR1 PF14381.6 EAX82598.1 - 0.047 13.4 0.1 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 MeaB PF03308.16 EAX82598.1 - 0.21 10.5 0.8 0.38 9.7 0.8 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF445 PF04286.12 EAX82598.1 - 0.23 11.2 7.4 0.37 10.5 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX82598.1 - 0.67 10.4 0.0 0.67 10.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) Pkinase PF00069.25 EAX82599.1 - 1.1e-77 261.0 0.0 1.3e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX82599.1 - 4.5e-35 121.2 0.1 2.5e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAX82599.1 - 0.025 13.9 0.0 1.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 EAX82599.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3839 PF12943.7 EAX82600.1 - 4.6e-155 514.1 15.8 5.6e-155 513.8 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4917 PF16263.5 EAX82600.1 - 0.015 14.7 0.2 0.027 13.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4917) Fez1 PF06818.15 EAX82600.1 - 0.052 14.0 1.7 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX82600.1 - 0.24 11.7 3.3 0.74 10.1 0.1 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX82600.1 - 0.71 10.4 7.2 1.9 9.0 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82601.1 - 1.5e-158 525.5 13.9 1.9e-158 525.2 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82601.1 - 1.1 9.9 5.2 0.35 11.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82601.1 - 1.3 9.6 7.7 1.5 9.3 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX82602.1 - 4.1e-08 33.1 0.1 4.9e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain CooT PF10133.9 EAX82603.1 - 0.14 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT T5orf172 PF10544.9 EAX82604.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82605.1 - 1.5e-35 121.5 0.8 2.8e-35 120.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82605.1 - 0.029 14.6 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX82605.1 - 3.5 8.2 8.7 13 6.3 3.6 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX82606.1 - 1.5e-06 27.9 2.2 1.5e-06 27.9 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82606.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82606.1 - 7e-05 22.6 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82606.1 - 0.00018 21.6 3.5 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82606.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82606.1 - 0.0014 18.4 0.5 0.0032 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82606.1 - 0.0019 17.8 0.4 0.014 15.1 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82606.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX82606.1 - 0.072 12.6 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82606.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82606.1 - 0.097 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82606.1 - 0.4 10.9 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX82607.1 - 0.0036 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase HD_3 PF13023.6 EAX82608.1 - 0.066 13.1 0.6 0.095 12.6 0.6 1.2 1 0 0 1 1 1 0 HD domain Pox_A32 PF04665.12 EAX82610.1 - 2e-07 30.8 0.5 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX82610.1 - 0.058 13.0 0.1 1.3 8.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX82610.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX82610.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.8 EAX82611.1 - 0.0023 17.6 0.0 0.0066 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX82611.1 - 0.19 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4108 PF13390.6 EAX82612.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX82614.1 - 0.0015 18.4 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX82614.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82614.1 - 0.0016 18.4 0.1 0.0022 18.0 0.1 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX82614.1 - 0.0037 17.6 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82614.1 - 0.024 14.1 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX82614.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX82614.1 - 0.075 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 EAX82614.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EAX82614.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX82616.1 - 1.9e-15 56.7 0.1 3.7e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX82617.1 - 3.5e-154 511.3 12.4 4.3e-154 511.0 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82617.1 - 0.021 15.2 4.1 0.26 11.8 0.1 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX82617.1 - 0.056 13.9 0.9 0.26 11.7 0.2 2.0 2 0 0 2 2 2 0 Fez1 DNA_pol_B_2 PF03175.13 EAX82618.1 - 8.6e-09 34.8 1.2 1.5e-08 33.9 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX82618.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX82618.1 - 0.16 12.0 0.0 0.95 9.5 0.0 2.1 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF1043 PF06295.12 EAX82619.1 - 0.023 14.7 0.3 0.032 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2400 PF09674.10 EAX82619.1 - 0.04 13.9 0.4 0.059 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX82619.1 - 0.045 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX82620.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX82620.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX82621.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAX82623.1 - 0.054 13.9 1.5 0.076 13.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82623.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX82629.1 - 1.3e-155 516.0 11.4 1.6e-155 515.7 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82629.1 - 0.023 15.1 1.0 0.065 13.7 0.2 1.9 2 0 0 2 2 2 0 Fez1 DUF29 PF01724.16 EAX82629.1 - 0.035 14.4 0.1 0.11 12.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 Rx_N PF18052.1 EAX82629.1 - 0.067 13.5 0.4 2.1 8.7 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82629.1 - 0.91 10.0 6.0 5.2 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82629.1 - 6.8 7.1 7.5 12 6.3 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal AAA_11 PF13086.6 EAX82630.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX82630.1 - 0.0034 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82630.1 - 0.0038 17.6 0.0 0.0057 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82630.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX82630.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX82630.1 - 0.04 13.5 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX82630.1 - 0.066 12.9 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX82630.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX82631.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82631.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82631.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82631.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX82632.1 - 2e-41 140.4 0.6 3.6e-41 139.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82632.1 - 0.0081 16.8 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Parathyroid hormone family KilA-N PF04383.13 EAX82633.1 - 6.6e-18 64.6 0.0 7.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX82634.1 - 2.4e-65 220.3 5.7 3.3e-65 219.9 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82634.1 - 0.017 15.6 0.4 0.021 15.3 0.4 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX82634.1 - 0.056 14.0 0.6 0.078 13.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) BRE1 PF08647.11 EAX82634.1 - 0.53 10.4 4.3 2.8 8.1 1.8 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3839 PF12943.7 EAX82635.1 - 1.1e-154 513.0 12.2 1.3e-154 512.6 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82635.1 - 0.042 14.1 0.6 1.6 9.0 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX82635.1 - 0.094 12.6 1.2 0.36 10.7 0.8 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82635.1 - 4.3 7.9 7.1 3.3 8.2 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX82636.1 - 4.7e-59 198.4 5.2 5.2e-59 198.3 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX82636.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide AAA_22 PF13401.6 EAX82638.1 - 5.3e-05 23.5 0.1 0.00033 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82638.1 - 8.4e-05 22.6 3.0 0.00015 21.8 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82638.1 - 0.00049 19.9 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82638.1 - 0.0007 19.5 0.8 0.0023 17.8 0.8 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82638.1 - 0.0046 16.7 0.3 0.37 10.5 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX82638.1 - 0.0072 16.7 0.0 0.0097 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82638.1 - 0.043 13.3 0.1 0.12 11.8 0.0 1.7 1 1 0 2 2 2 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX82638.1 - 0.051 13.2 0.7 0.085 12.5 0.3 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase DUF1827 PF08860.10 EAX82638.1 - 0.11 12.8 3.4 4.1 7.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TrmK PF04816.12 EAX82638.1 - 0.11 12.1 2.4 0.2 11.2 2.4 1.5 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase AAA PF00004.29 EAX82638.1 - 0.12 12.8 0.1 0.45 10.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX82638.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX82638.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gly-zipper_Omp PF13488.6 EAX82640.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX82640.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82640.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4106 PF13388.6 EAX82642.1 - 7.5e-249 825.9 37.5 1.1e-129 433.4 20.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX82642.1 - 0.061 13.1 1.5 0.068 13.0 0.2 1.7 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX82642.1 - 7.3 6.5 38.7 0.51 10.3 24.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PSP PF04046.16 EAX82643.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNTTIP1_dimer PF18192.1 EAX82644.1 - 0.068 13.5 1.5 0.15 12.4 1.5 1.5 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain Phage_int_SAM_4 PF13495.6 EAX82645.1 - 5.5e-05 23.6 0.9 0.026 15.0 0.0 2.1 1 1 1 2 2 2 2 Phage integrase, N-terminal SAM-like domain HAUS5 PF14817.6 EAX82646.1 - 0.062 12.1 6.3 0.069 11.9 6.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Gly-zipper_Omp PF13488.6 EAX82647.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX82647.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX82647.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Apolipoprotein PF01442.18 EAX82648.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4107 PF13389.6 EAX82649.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX82650.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Myb_DNA-binding PF00249.31 EAX82651.1 - 5.1e-29 100.2 0.9 2.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82651.1 - 3.3e-24 84.9 2.2 4.4e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX82651.1 - 0.00012 22.0 0.7 0.18 11.9 1.0 2.5 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX82651.1 - 0.0036 17.5 0.9 0.0073 16.5 0.5 1.7 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX82651.1 - 0.0079 16.1 1.1 0.0079 16.1 1.1 2.0 1 1 1 2 2 2 1 Myb DNA-binding like DUF3685 PF12452.8 EAX82651.1 - 0.038 13.7 0.6 0.046 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) AHJR-like PF18743.1 EAX82651.1 - 0.053 13.1 0.1 0.093 12.3 0.0 1.5 1 1 0 1 1 1 0 REase_AHJR-like Mito_fiss_Elm1 PF06258.11 EAX82651.1 - 0.11 11.7 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Skp1 PF01466.19 EAX82651.1 - 5.4 7.2 5.9 11 6.2 0.0 3.4 3 1 0 3 3 3 0 Skp1 family, dimerisation domain GPS2_interact PF15784.5 EAX82653.1 - 0.033 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX82655.1 - 4.3e-11 42.7 0.7 7e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Ly49 PF08391.10 EAX82656.1 - 1.3 9.4 4.8 0.71 10.2 3.0 1.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Pox_A32 PF04665.12 EAX82657.1 - 1.7e-07 31.0 3.0 2.5e-07 30.4 3.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82657.1 - 0.0032 17.1 0.3 0.0039 16.9 0.3 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82657.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82657.1 - 0.059 13.1 0.2 0.42 10.3 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein TrmK PF04816.12 EAX82657.1 - 0.17 11.4 2.8 0.28 10.7 2.8 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase APG12 PF04110.13 EAX82657.1 - 0.3 11.5 2.5 0.39 11.2 1.2 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF2666 PF10869.8 EAX82657.1 - 0.54 10.5 9.5 5.9 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX82658.1 - 1.7e-33 114.8 0.0 1.7e-33 114.8 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82658.1 - 0.0055 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) TMEM154 PF15102.6 EAX82659.1 - 4 7.3 6.8 4.8 7.1 6.8 1.1 1 0 0 1 1 1 0 TMEM154 protein family Collagen_bind_2 PF12904.7 EAX82661.1 - 0.12 12.3 0.0 3.6 7.6 0.0 2.1 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase MbeD_MobD PF04899.12 EAX82662.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 MbeD/MobD like DUF3464 PF11947.8 EAX82663.1 - 0.48 10.2 2.7 0.48 10.2 1.8 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX82664.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX82665.1 - 1.5e-51 172.3 35.4 4.5e-33 113.1 14.6 4.9 3 2 2 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX82665.1 - 0.14 11.9 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) T5orf172 PF10544.9 EAX82666.1 - 0.00081 19.9 0.2 0.0018 18.8 0.2 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX82666.1 - 0.012 15.2 0.2 0.093 12.2 0.0 1.9 2 0 0 2 2 2 0 Legume lectin domain T5orf172 PF10544.9 EAX82667.1 - 0.00035 21.1 0.0 0.00089 19.8 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX82667.1 - 0.0073 15.9 0.2 0.048 13.2 0.1 1.9 2 0 0 2 2 2 1 Legume lectin domain DUF4107 PF13389.6 EAX82669.1 - 1.5e-71 239.8 3.5 2.3e-71 239.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX82670.1 - 0.0027 17.4 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX82674.1 - 9.9e-156 516.3 14.1 1.1e-155 516.2 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82674.1 - 0.068 13.6 1.8 0.43 11.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82674.1 - 0.35 11.4 8.0 1.5 9.3 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX82674.1 - 1.3 9.3 5.3 9.7 6.6 0.1 3.4 2 2 2 4 4 4 0 Tup N-terminal AAA_22 PF13401.6 EAX82675.1 - 7.4e-05 23.0 0.1 0.0004 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82675.1 - 8.4e-05 22.6 2.9 0.00018 21.6 2.9 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82675.1 - 0.0005 19.9 0.0 0.00077 19.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82675.1 - 0.001 18.9 0.9 0.0029 17.5 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82675.1 - 0.0086 16.4 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82675.1 - 0.011 15.4 0.2 1.3 8.8 0.0 2.7 1 1 1 3 3 3 0 IstB-like ATP binding protein PhoH PF02562.16 EAX82675.1 - 0.053 13.0 0.1 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX82675.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX82675.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX82675.1 - 0.12 12.8 0.0 0.45 10.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAX82675.1 - 0.25 11.0 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Phage_Coat_A PF05357.13 EAX82676.1 - 0.014 15.1 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Phage Coat Protein A EpuA PF11772.8 EAX82676.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Gln-synt_N PF03951.19 EAX82676.1 - 0.05 13.3 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain DUF3839 PF12943.7 EAX82677.1 - 5.3e-124 412.4 8.5 6.1e-124 412.2 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LMBR1 PF04791.16 EAX82677.1 - 0.15 10.9 0.3 0.18 10.7 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2547 PF10818.8 EAX82677.1 - 0.21 12.5 1.4 5.6 8.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2547) KELK PF15796.5 EAX82677.1 - 0.33 11.4 4.4 1.1 9.8 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX82678.1 - 0.0036 16.9 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX82679.1 - 2.8e-71 238.9 3.6 3.8e-71 238.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX82681.1 - 3.7e-156 517.7 12.9 4.4e-156 517.5 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82681.1 - 0.19 11.6 1.3 0.53 10.1 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX82681.1 - 0.39 11.0 3.4 1.6 9.1 0.0 3.0 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82681.1 - 0.39 11.2 5.2 4.6 7.8 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82681.1 - 1.3 9.5 4.6 1.6 9.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX82682.1 - 0.00012 22.0 8.9 0.00014 21.8 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phi-29_GP4 PF05464.11 EAX82682.1 - 0.072 13.4 1.3 0.15 12.3 0.2 2.0 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Arf PF00025.21 EAX82683.1 - 7.8e-41 139.4 0.1 9.1e-41 139.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX82683.1 - 1.1e-14 54.7 0.0 1.8e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX82683.1 - 3.1e-14 52.9 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EAX82683.1 - 5.7e-10 39.3 0.1 1.8e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX82683.1 - 7.8e-07 28.7 0.0 9.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX82683.1 - 2e-05 23.9 1.2 0.0048 16.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX82683.1 - 3e-05 23.5 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX82683.1 - 8.4e-05 22.5 0.4 0.11 12.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 EAX82683.1 - 0.00019 22.0 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 EAX82683.1 - 0.00022 20.8 0.1 0.081 12.5 0.0 2.2 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAX82683.1 - 0.0046 17.0 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Virul_Fac PF10139.9 EAX82683.1 - 0.059 11.6 0.0 0.075 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor AAA_29 PF13555.6 EAX82683.1 - 0.063 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EAX82683.1 - 0.081 13.2 0.2 0.91 9.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EAX82683.1 - 0.14 11.7 0.5 0.29 10.7 0.5 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 EAX82683.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX82684.1 - 7.9e-26 91.0 7.3 1.3e-25 90.3 7.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX82684.1 - 0.16 12.4 0.9 0.85 10.1 0.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB Trypan_PARP PF05887.11 EAX82686.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82686.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin VirK PF06903.12 EAX82688.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 VirK protein MFS_1 PF07690.16 EAX82689.1 - 5.6e-29 101.2 17.6 6.1e-29 101.0 17.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAX82689.1 - 0.00024 20.1 14.3 0.00024 20.1 14.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EAX82689.1 - 0.17 10.1 6.1 0.65 8.2 0.9 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4225 PF13988.6 EAX82689.1 - 0.47 10.0 4.5 0.13 11.8 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) MFS_1 PF07690.16 EAX82690.1 - 3.3e-05 23.0 0.0 3.5e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pox_A32 PF04665.12 EAX82695.1 - 5.3e-07 29.4 2.8 7.8e-07 28.8 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82695.1 - 0.0046 16.6 0.1 0.007 16.0 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82695.1 - 0.046 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82695.1 - 0.064 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82695.1 - 0.086 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX82695.1 - 0.12 12.8 3.5 0.52 10.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX82695.1 - 0.2 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82695.1 - 0.46 10.7 8.6 5.6 7.2 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX82696.1 - 6.5e-31 106.5 0.3 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX82697.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82698.1 - 1.5e-41 140.8 0.3 3.9e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82698.1 - 0.012 16.2 0.6 0.038 14.6 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX82699.1 - 6.6e-07 29.0 2.2 6.6e-07 29.0 2.2 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82699.1 - 3.1e-05 23.8 0.4 0.3 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82699.1 - 4.5e-05 23.7 0.2 0.00033 20.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82699.1 - 0.00029 20.9 4.3 0.00061 19.8 3.8 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82699.1 - 0.00072 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82699.1 - 0.0036 17.1 1.9 0.0053 16.6 1.0 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82699.1 - 0.0054 16.4 2.7 0.015 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82699.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX82699.1 - 0.082 13.0 0.6 1.2 9.2 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX82699.1 - 0.091 12.3 0.0 0.3 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82699.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82699.1 - 0.11 13.0 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82699.1 - 0.33 11.2 4.8 4.3 7.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX82699.1 - 0.91 10.2 11.7 0.43 11.3 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 GDE_C PF06202.14 EAX82700.1 - 0.046 12.7 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase PRA-PH PF01503.17 EAX82700.1 - 0.17 12.3 3.4 10 6.6 3.5 2.8 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Annexin PF00191.20 EAX82700.1 - 0.26 11.4 1.1 1.2 9.3 0.2 2.6 2 1 0 2 2 2 0 Annexin Myb_DNA-binding PF00249.31 EAX82701.1 - 6.5e-24 83.9 0.1 1.7e-12 47.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82701.1 - 1.1e-18 67.2 1.4 5.7e-15 55.3 0.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX82701.1 - 8.9e-06 25.7 0.2 0.052 13.6 0.1 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX82701.1 - 0.0003 20.6 0.3 0.037 13.9 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX82701.1 - 0.092 12.9 0.8 1.6 8.9 0.0 2.9 3 1 0 3 3 3 0 Rap1 Myb domain PriCT_2 PF08707.11 EAX82701.1 - 0.13 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) DUF4107 PF13389.6 EAX82702.1 - 4.8e-66 221.9 13.2 1.4e-64 217.2 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82702.1 - 0.097 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX82703.1 - 1.8e-41 140.5 1.3 2.9e-41 139.8 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX82703.1 - 0.13 12.2 6.3 0.25 11.3 6.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 T5orf172 PF10544.9 EAX82704.1 - 3.5e-06 27.5 0.3 7.7e-06 26.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX82705.1 - 6.7e-73 244.2 4.5 8e-73 243.9 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82705.1 - 0.053 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX82705.1 - 0.18 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX82709.1 - 4.2e-47 158.0 29.7 1.4e-31 108.4 13.4 3.7 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX82709.1 - 0.016 14.9 0.7 0.11 12.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) nsp9 PF08710.10 EAX82709.1 - 0.96 9.9 4.2 0.92 9.9 0.1 2.8 2 1 0 2 2 2 0 nsp9 replicase TPR_MLP1_2 PF07926.12 EAX82710.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX82710.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX82710.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family GPS2_interact PF15784.5 EAX82711.1 - 0.05 14.0 1.3 0.067 13.6 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82711.1 - 0.13 11.2 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX82713.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4108 PF13390.6 EAX82714.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX82715.1 - 1.3 9.0 5.8 0.11 12.4 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF3839 PF12943.7 EAX82716.1 - 1.4e-118 394.7 11.4 1.7e-118 394.4 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82716.1 - 0.014 15.8 2.3 1.8 9.0 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82716.1 - 0.11 13.1 1.8 0.16 12.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX82717.1 - 1.1e-42 144.4 0.5 2.4e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82717.1 - 0.0064 17.1 0.1 0.039 14.6 0.0 2.1 1 1 1 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX82718.1 - 2.7e-07 30.3 2.7 3.6e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82718.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82718.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82718.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82718.1 - 0.086 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX82718.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX82718.1 - 0.55 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) EpuA PF11772.8 EAX82719.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta T5orf172 PF10544.9 EAX82720.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82721.1 - 1.2e-33 115.3 0.3 2.9e-33 114.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82721.1 - 0.028 15.0 0.0 0.078 13.6 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family Ycf34 PF10718.9 EAX82721.1 - 0.043 14.5 1.4 17 6.2 0.2 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 SR-25 PF10500.9 EAX82723.1 - 0.0023 17.6 10.4 0.0023 17.6 10.4 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Oxysterol_BP PF01237.18 EAX82723.1 - 0.012 14.5 5.3 0.013 14.3 5.3 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein DUF755 PF05501.11 EAX82723.1 - 0.13 12.5 12.3 0.15 12.4 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BROMI PF14961.6 EAX82723.1 - 0.87 6.9 3.6 0.93 6.8 3.6 1.0 1 0 0 1 1 1 0 Broad-minded protein Atrophin-1 PF03154.15 EAX82723.1 - 1.8 6.7 11.6 1.9 6.6 11.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Phage_Gp23 PF10669.9 EAX82723.1 - 3.2 8.1 7.0 3.7 7.9 7.0 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Presenilin PF01080.17 EAX82723.1 - 10 4.8 5.8 11 4.6 5.8 1.0 1 0 0 1 1 1 0 Presenilin DUF3839 PF12943.7 EAX82724.1 - 4.4e-148 491.3 10.2 5.8e-148 490.9 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82724.1 - 0.014 15.9 0.3 0.044 14.2 0.0 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82724.1 - 0.1 13.0 1.2 5.3 7.6 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX82724.1 - 0.19 11.6 1.3 0.52 10.1 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX82725.1 - 1.2e-40 139.3 4.0 1.3e-40 139.2 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX82725.1 - 0.061 13.7 0.6 0.082 13.3 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX82726.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase LRV PF01816.17 EAX82727.1 - 1.6 9.3 7.3 21 5.8 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat variant Cytadhesin_P30 PF07271.11 EAX82729.1 - 4.4 6.8 17.8 5.7 6.4 17.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF3839 PF12943.7 EAX82730.1 - 1.9e-157 521.9 15.2 2.4e-157 521.6 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) UPF0242 PF06785.11 EAX82730.1 - 0.0041 17.3 1.2 0.0041 17.3 1.2 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus KELK PF15796.5 EAX82730.1 - 0.36 11.3 9.8 2.1 8.9 0.7 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82730.1 - 0.58 10.7 8.8 0.073 13.6 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX82730.1 - 6 7.4 7.5 0.56 10.7 1.5 2.3 3 0 0 3 3 3 0 Cell division protein ZapB DUF2121 PF09894.9 EAX82731.1 - 0.6 9.6 4.4 1.6 8.2 4.4 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) RNA_pol_Rpb1_2 PF00623.20 EAX82734.1 - 1.7e-61 207.3 0.0 4e-61 206.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 EAX82734.1 - 1.5e-57 195.1 8.8 3.5e-57 193.9 7.3 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 EAX82734.1 - 1.1e-32 113.2 0.3 2.8e-32 111.8 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAX82734.1 - 3.8e-22 78.3 0.1 3.8e-22 78.3 0.1 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 CobT PF06213.12 EAX82734.1 - 0.0094 15.4 9.5 0.013 14.9 8.7 1.6 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DDHD PF02862.17 EAX82734.1 - 0.16 12.1 3.2 0.34 11.0 3.2 1.5 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 EAX82734.1 - 0.2 11.4 4.1 0.37 10.5 4.1 1.3 1 0 0 1 1 1 0 Connexin zinc_ribbon_6 PF14599.6 EAX82734.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon NOA36 PF06524.12 EAX82734.1 - 2.2 7.5 12.3 3.8 6.7 12.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF641 PF04859.12 EAX82735.1 - 0.031 14.6 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX82735.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor DUF3839 PF12943.7 EAX82737.1 - 1.9e-139 463.0 8.3 2.4e-139 462.7 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX82737.1 - 0.11 12.9 2.3 2.5 8.6 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta zf_CopZ PF18423.1 EAX82737.1 - 0.17 11.9 0.3 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Zinc binding domain KELK PF15796.5 EAX82737.1 - 1 9.9 6.3 2 8.9 0.7 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82738.1 - 3.2e-06 27.6 0.1 7.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82738.1 - 0.0081 16.0 2.4 0.049 13.5 1.2 2.6 2 1 0 2 2 2 1 KilA-N domain FRG PF08867.11 EAX82738.1 - 0.11 13.4 0.1 2 9.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain T5orf172 PF10544.9 EAX82739.1 - 7.5e-07 29.6 0.3 2.1e-06 28.2 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82739.1 - 0.015 15.1 0.2 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX82739.1 - 0.059 12.9 1.0 0.63 9.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX82740.1 - 5.4e-78 261.8 11.1 7e-78 261.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX82740.1 - 0.0055 16.7 0.8 2.6 8.1 0.0 2.3 1 1 1 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4107 PF13389.6 EAX82741.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Myb_DNA-binding PF00249.31 EAX82742.1 - 1.8e-27 95.3 1.8 9.9e-13 48.1 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82742.1 - 5.3e-22 77.8 5.8 4.3e-14 52.5 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX82742.1 - 1.6e-06 27.9 2.3 0.0011 18.8 0.3 2.5 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX82742.1 - 1.9e-05 24.7 0.4 0.047 13.7 0.0 3.1 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX82742.1 - 8.9e-05 22.6 1.7 0.015 15.5 0.1 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX82742.1 - 0.092 12.9 0.1 15 5.9 0.1 2.7 2 1 0 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.8 EAX82742.1 - 0.11 12.6 0.2 1.3 9.2 0.1 2.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EF-hand_1 PF00036.32 EAX82743.1 - 2.4e-16 58.0 0.8 0.00057 19.3 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EAX82743.1 - 4.9e-14 51.0 0.2 0.0011 18.7 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EAX82743.1 - 1.2e-11 44.8 0.4 8.3e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX82743.1 - 3.5e-09 35.8 1.0 0.00014 21.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EAX82743.1 - 4e-07 29.8 1.6 0.097 12.5 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair PSP PF04046.16 EAX82744.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX82745.1 - 0.089 12.7 3.9 0.1 12.5 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) HTH_12 PF08461.10 EAX82748.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain LRR_5 PF13306.6 EAX82749.1 - 1.7e-08 34.5 17.5 0.0021 18.0 0.6 3.3 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DNA_pol_B_2 PF03175.13 EAX82750.1 - 7.1e-37 127.4 13.8 3.3e-36 125.2 13.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Collagen PF01391.18 EAX82750.1 - 3.2e-05 23.6 10.6 5e-05 23.0 10.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Trypan_PARP PF05887.11 EAX82754.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX82754.1 - 2 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX82755.1 - 0.041 14.3 0.5 0.049 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX82756.1 - 6e-41 138.8 0.1 6e-41 138.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX82756.1 - 0.011 15.0 0.2 0.038 13.2 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase DUF3213 PF11491.8 EAX82756.1 - 0.017 15.3 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX82756.1 - 0.13 10.8 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX82757.1 - 6.6e-08 32.3 0.9 8e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82757.1 - 0.003 17.2 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82757.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82757.1 - 0.091 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX82757.1 - 0.13 12.7 1.3 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF3839 PF12943.7 EAX82758.1 - 7.4e-101 336.6 8.0 8.6e-101 336.4 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82758.1 - 0.024 14.1 0.6 0.032 13.7 0.5 1.2 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX82758.1 - 0.53 10.9 4.1 0.76 10.4 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Pox_A32 PF04665.12 EAX82759.1 - 3e-05 23.6 3.1 3.4e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX82759.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX82759.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX82759.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DDE_1 PF03184.19 EAX82760.1 - 9.7e-13 48.1 0.0 2.1e-12 47.1 0.0 1.4 1 1 1 2 2 2 1 DDE superfamily endonuclease PapD_N PF00345.20 EAX82762.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX82762.1 - 0.053 13.5 0.5 0.08 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX82762.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) T5orf172 PF10544.9 EAX82764.1 - 0.00019 21.9 0.4 0.00051 20.5 0.4 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX82764.1 - 0.0063 16.1 1.1 0.1 12.1 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX82764.1 - 0.013 15.3 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX82765.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX82765.1 - 0.06 13.5 0.2 0.32 11.2 0.2 2.2 1 1 0 1 1 1 0 Associated with zinc fingers GPS2_interact PF15784.5 EAX82768.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_A32 PF04665.12 EAX82769.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82769.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82769.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82769.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82769.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82769.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82769.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82769.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82769.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82769.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82769.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82769.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX82770.1 - 4.2e-157 520.8 14.5 5.4e-157 520.5 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82770.1 - 0.1 13.0 2.0 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82770.1 - 1 9.8 7.7 2.2 8.8 0.9 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX82771.1 - 0.034 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX82772.1 - 7.7e-67 224.5 2.5 1e-66 224.1 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX82773.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX82774.1 - 5.1e-82 275.0 5.5 5.7e-82 274.8 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX82775.1 - 2.2e-155 515.2 15.1 2.8e-155 514.8 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82775.1 - 0.11 12.9 2.2 0.14 12.6 0.6 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82775.1 - 0.28 11.7 6.8 2 8.9 0.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Myb_DNA-binding PF00249.31 EAX82776.1 - 1.9e-24 85.6 1.5 2e-11 43.9 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82776.1 - 1.7e-21 76.2 1.2 2.3e-12 46.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX82776.1 - 1.5e-05 24.8 0.3 0.0075 16.1 0.2 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EAX82776.1 - 0.036 14.1 0.2 0.76 9.9 0.1 2.7 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EAX82776.1 - 0.076 13.0 0.1 8.3 6.5 0.0 2.8 2 1 0 2 2 2 0 SLIDE DEAD_assoc PF08494.11 EAX82776.1 - 0.13 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 DEAD/H associated Ank_2 PF12796.7 EAX82777.1 - 1.5e-34 118.4 1.4 7e-15 55.4 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82777.1 - 4.9e-34 116.3 3.6 5.1e-10 39.7 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX82777.1 - 7.7e-31 105.8 0.3 3.8e-07 30.2 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82777.1 - 2.4e-26 88.9 1.6 6.4e-05 23.1 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX82777.1 - 1e-23 82.7 2.8 0.00028 21.2 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX82777.1 - 0.0031 17.4 1.4 1.8 8.6 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DNA_pol_B_2 PF03175.13 EAX82778.1 - 3.6e-09 36.0 1.2 5.4e-09 35.4 1.2 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX82778.1 - 0.054 13.5 0.0 0.5 10.4 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX82778.1 - 0.066 12.8 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 PadR PF03551.14 EAX82780.1 - 0.043 13.8 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX82782.1 - 2.8e-58 195.9 5.2 3.1e-58 195.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX82782.1 - 0.092 13.0 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX82783.1 - 3.1e-07 30.1 2.6 4.6e-07 29.6 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82783.1 - 0.0034 17.1 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX82783.1 - 0.046 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82783.1 - 0.063 13.0 0.1 0.32 10.7 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82783.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX82783.1 - 0.12 12.8 3.5 0.52 10.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF2666 PF10869.8 EAX82783.1 - 0.42 10.8 8.5 5.8 7.1 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX82784.1 - 3e-158 524.5 15.7 3.5e-158 524.3 15.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82784.1 - 2.2 8.8 7.9 1.9 9.0 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LRR_5 PF13306.6 EAX82785.1 - 2.1e-09 37.4 2.2 5.4e-06 26.4 0.5 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Pox_A32 PF04665.12 EAX82786.1 - 5.3e-07 29.3 2.4 5.3e-07 29.3 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82786.1 - 0.00013 22.3 0.3 0.00074 19.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82786.1 - 0.00077 19.5 4.4 0.0018 18.3 4.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX82786.1 - 0.0016 18.2 0.5 0.33 10.7 0.1 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein Zot PF05707.12 EAX82786.1 - 0.0026 17.4 0.5 0.013 15.2 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) DEAD PF00270.29 EAX82786.1 - 0.005 16.6 0.1 0.011 15.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase NYN PF01936.18 EAX82786.1 - 0.013 16.0 0.3 1 9.9 0.0 2.8 2 1 1 3 3 3 0 NYN domain AAA_19 PF13245.6 EAX82786.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAX82786.1 - 0.11 12.3 0.8 0.25 11.1 0.8 1.7 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX82786.1 - 0.39 11.0 4.1 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pro-NT_NN PF07421.11 EAX82788.1 - 0.01 16.1 1.0 0.01 16.1 1.0 1.0 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor MAJIN PF15077.6 EAX82788.1 - 4 7.2 8.9 4.1 7.1 8.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein PWI PF01480.17 EAX82789.1 - 0.027 14.8 0.1 0.051 13.9 0.1 1.4 1 0 0 1 1 1 0 PWI domain DUF2939 PF11159.8 EAX82790.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX82790.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX82791.1 - 0.024 14.7 0.2 0.034 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX82792.1 - 1.2e-23 83.7 7.0 6.3e-23 81.4 7.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PSP PF04046.16 EAX82793.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX82794.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82794.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAX82796.1 - 0.026 14.4 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX82796.1 - 0.063 13.3 0.4 0.086 12.8 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX82797.1 - 0.011 16.1 0.6 0.013 15.9 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX82797.1 - 1.5 7.8 2.9 1.5 7.8 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX82797.1 - 2.6 8.1 5.7 2.8 7.9 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX82798.1 - 0.009 16.0 0.4 0.013 15.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF3839 PF12943.7 EAX82799.1 - 3.9e-156 517.6 12.9 5e-156 517.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX82799.1 - 0.049 14.3 0.7 0.32 11.6 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX82799.1 - 6.3 7.3 7.6 2.9 8.4 0.4 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX82800.1 - 1.3e-06 28.1 2.4 1.3e-06 28.1 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82800.1 - 3.7e-05 24.0 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82800.1 - 5.2e-05 23.1 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82800.1 - 0.00016 21.7 3.9 0.0004 20.4 3.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82800.1 - 0.00041 20.1 0.1 0.00078 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82800.1 - 0.0014 18.5 0.5 0.0031 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82800.1 - 0.0019 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82800.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX82800.1 - 0.073 12.6 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX82800.1 - 0.084 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX82800.1 - 0.087 12.3 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82800.1 - 0.096 13.1 0.1 0.78 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX82800.1 - 0.17 12.3 2.8 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX82800.1 - 0.42 10.9 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82801.1 - 6.8e-40 135.4 1.2 1.2e-39 134.7 0.2 2.0 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82801.1 - 0.0022 18.6 0.1 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 Parathyroid hormone family zf-RING_9 PF13901.6 EAX82801.1 - 0.14 12.1 0.2 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon RRP36 PF06102.12 EAX82801.1 - 3 7.8 11.3 0.6 10.0 3.6 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 ANAPC15 PF15243.6 EAX82801.1 - 3.2 8.2 8.6 8.6 6.8 3.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 T5orf172 PF10544.9 EAX82802.1 - 4.8e-06 27.0 0.3 1.1e-05 25.9 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain ANAPC4_WD40 PF12894.7 EAX82803.1 - 0.0052 17.1 0.0 0.029 14.6 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX82803.1 - 0.0074 17.1 2.5 2.5 9.1 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Pentapeptide_2 PF01469.18 EAX82804.1 - 0.0032 17.3 1.0 8 6.4 0.1 3.0 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) NTPase_P4 PF11602.8 EAX82804.1 - 2.4 7.3 6.7 2 7.5 1.9 2.1 1 1 1 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Gly-zipper_Omp PF13488.6 EAX82805.1 - 0.02 14.9 10.4 0.035 14.1 10.4 1.4 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX82805.1 - 0.54 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MULE PF10551.9 EAX82806.1 - 8.7e-11 42.1 0.1 2.6e-10 40.6 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain HTH_Tnp_1_2 PF13022.6 EAX82806.1 - 0.0086 16.2 3.1 0.043 14.0 0.6 2.6 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase Salp15 PF12115.8 EAX82806.1 - 0.87 10.0 3.1 0.34 11.4 0.3 1.7 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation LRR_5 PF13306.6 EAX82807.1 - 2.3e-76 253.9 49.0 3.8e-21 75.4 5.2 5.1 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX82807.1 - 5.2e-22 77.4 0.3 0.0026 17.5 0.0 7.9 5 3 4 9 9 9 8 Leucine rich repeat Sec7 PF01369.20 EAX82808.1 - 7.9e-10 38.7 0.4 1.3e-09 38.0 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EAX82808.1 - 0.15 12.5 0.3 0.3 11.6 0.3 1.5 1 0 0 1 1 1 0 PH domain Pox_A32 PF04665.12 EAX82810.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82810.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82810.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82810.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX82811.1 - 5.2e-06 26.1 2.7 7.2e-06 25.6 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82811.1 - 0.0038 16.9 0.1 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX82811.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Elong_Iki1 PF10483.9 EAX82811.1 - 0.037 13.5 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX82811.1 - 0.05 13.3 0.2 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX82811.1 - 0.067 12.9 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX82811.1 - 0.15 12.0 2.4 1.1 9.2 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX82811.1 - 0.32 11.4 2.4 0.43 11.0 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF2666 PF10869.8 EAX82811.1 - 0.33 11.2 8.6 4.8 7.4 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX82812.1 - 1.9e-44 150.1 0.3 4.7e-44 148.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82812.1 - 0.1 13.2 0.3 0.31 11.7 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX82813.1 - 1.1e-06 29.1 0.1 2.6e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82813.1 - 0.014 15.3 1.1 0.028 14.2 0.4 2.0 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX82814.1 - 2.8e-93 311.9 7.9 3.1e-93 311.7 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82814.1 - 0.036 13.6 0.4 0.042 13.4 0.4 1.2 1 0 0 1 1 1 0 Z1 domain DUF3839 PF12943.7 EAX82815.1 - 6.7e-80 268.0 9.5 8.6e-80 267.7 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5446 PF17522.2 EAX82816.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) KilA-N PF04383.13 EAX82817.1 - 5e-39 132.6 0.9 1.3e-38 131.3 0.1 2.1 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX82819.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82820.1 - 5e-33 113.3 0.4 1.2e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82820.1 - 0.0036 17.4 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX82821.1 - 8.8e-07 28.6 2.2 8.8e-07 28.6 2.2 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82821.1 - 2.9e-05 23.9 0.2 0.34 10.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82821.1 - 4.9e-05 23.6 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82821.1 - 0.00021 21.4 3.4 0.00042 20.3 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82821.1 - 0.00077 19.3 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82821.1 - 0.0014 18.4 0.4 0.003 17.4 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82821.1 - 0.018 15.4 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX82821.1 - 0.027 14.1 2.4 0.054 13.1 0.5 2.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 EAX82821.1 - 0.096 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX82821.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82821.1 - 0.14 12.6 0.5 0.91 9.9 0.1 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX82821.1 - 0.83 10.3 11.5 0.29 11.8 1.4 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX82821.1 - 0.97 9.7 5.4 9.7 6.5 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX82821.1 - 7.1 6.9 14.9 2.9 8.1 0.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX82822.1 - 2.6e-155 514.9 12.2 3e-155 514.8 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82822.1 - 0.092 12.2 1.8 0.15 11.5 0.3 1.8 1 1 0 2 2 2 0 Z1 domain KELK PF15796.5 EAX82822.1 - 0.59 10.6 7.4 0.36 11.3 0.3 3.2 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82823.1 - 7.4e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX82824.1 - 5.2e-113 376.4 6.7 5.8e-113 376.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX82824.1 - 0.31 11.7 3.0 4.2 8.0 0.2 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5398) Myb_DNA-binding PF00249.31 EAX82826.1 - 2.2e-24 85.4 0.3 4.5e-11 42.8 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX82826.1 - 3.9e-22 78.3 6.2 4e-16 59.0 1.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Skp1 PF01466.19 EAX82826.1 - 0.011 15.8 0.1 9.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Myb_DNA-bind_2 PF08914.11 EAX82826.1 - 0.078 13.2 0.7 0.59 10.3 0.1 2.7 1 1 1 2 2 2 0 Rap1 Myb domain DUF3839 PF12943.7 EAX82827.1 - 9e-80 267.6 12.0 1.1e-79 267.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX82827.1 - 0.0007 19.0 0.5 0.0011 18.4 0.3 1.4 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Aminotran_1_2 PF00155.21 EAX82827.1 - 0.0014 17.9 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II NTP_transf_6 PF06042.11 EAX82827.1 - 0.019 14.8 1.5 0.061 13.2 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX82827.1 - 0.028 15.0 1.3 0.054 14.1 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 EAX82827.1 - 0.076 13.3 2.0 0.11 12.8 0.7 1.9 2 1 0 2 2 2 0 Tho complex subunit 7 PRD PF00874.20 EAX82827.1 - 0.095 13.0 1.2 0.39 11.0 0.1 2.4 3 0 0 3 3 3 0 PRD domain STAT_alpha PF01017.20 EAX82827.1 - 0.2 11.5 1.5 2.8 7.8 0.3 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Importin_rep PF18773.1 EAX82830.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF4107 PF13389.6 EAX82832.1 - 5.5e-68 228.2 2.8 7.2e-68 227.8 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX82833.1 - 1.2e-155 516.0 11.4 1.4e-155 515.8 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82833.1 - 0.033 14.6 6.9 0.62 10.6 0.5 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82835.1 - 3.2e-126 419.7 6.2 3.7e-126 419.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) SL4P PF17618.2 EAX82836.1 - 0.34 11.0 3.3 8.9 6.4 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX82838.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX82839.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_D5 PF03288.16 EAX82840.1 - 2.2e-05 24.9 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82840.1 - 0.055 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX82841.1 - 1.1e-57 194.0 8.9 1.2e-57 193.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_5 PF13306.6 EAX82843.1 - 3.7e-173 566.8 107.1 2.7e-39 134.1 8.6 5.6 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX82843.1 - 1.1e-21 76.3 0.0 0.029 14.1 0.1 9.5 3 1 7 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 EAX82843.1 - 6.5e-07 29.6 10.9 3.1 8.3 0.4 9.0 6 3 6 12 12 12 1 Leucine Rich repeats (2 copies) PTP_tm PF18861.1 EAX82843.1 - 0.0053 16.8 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J ZF-HD_dimer PF04770.12 EAX82843.1 - 0.021 15.2 0.0 55 4.2 0.0 4.4 4 1 0 4 4 4 0 ZF-HD protein dimerisation region Podoplanin PF05808.11 EAX82843.1 - 0.039 14.1 0.4 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 Podoplanin HRM PF02793.22 EAX82843.1 - 0.063 13.6 0.4 48 4.3 0.0 5.0 4 2 0 4 4 4 0 Hormone receptor domain SKG6 PF08693.10 EAX82843.1 - 5.9 6.4 9.6 11 5.5 9.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Thioredoxin PF00085.20 EAX82844.1 - 3e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAX82844.1 - 0.00043 19.7 0.1 0.00068 19.1 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EAX82844.1 - 0.048 13.9 0.2 0.72 10.1 0.1 2.8 3 0 0 3 3 3 0 Glutaredoxin DUF836 PF05768.14 EAX82844.1 - 0.055 13.9 0.3 0.21 12.0 0.0 2.3 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 EAX82844.1 - 0.095 12.9 0.2 0.27 11.4 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin Pox_D5 PF03288.16 EAX82845.1 - 5.1e-06 26.9 0.5 7.5e-06 26.4 0.5 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82845.1 - 0.015 15.9 0.1 0.02 15.5 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82845.1 - 0.037 14.0 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX82846.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX82847.1 - 0.11 12.7 4.2 0.14 12.4 4.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2897 PF11446.8 EAX82847.1 - 7.3 6.6 8.0 15 5.5 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX82848.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82848.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82848.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82848.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82848.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82848.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82848.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82848.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82848.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82848.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82848.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX82848.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX82849.1 - 1.6e-77 260.2 12.5 2.1e-77 259.9 12.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82849.1 - 0.06 13.6 0.8 0.15 12.3 0.1 2.0 2 1 1 3 3 3 0 Rx N-terminal domain PRD PF00874.20 EAX82849.1 - 0.068 13.5 0.5 0.74 10.2 0.0 2.6 2 1 1 3 3 3 0 PRD domain LD_cluster2 PF18163.1 EAX82849.1 - 0.13 11.7 1.0 0.91 9.0 0.0 2.4 2 1 1 3 3 3 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX82849.1 - 0.16 11.8 2.0 0.39 10.5 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX82850.1 - 6.5e-06 26.6 0.2 1.6e-05 25.3 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82851.1 - 3.2e-35 120.4 1.3 4.9e-35 119.8 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX82851.1 - 0.032 14.2 6.4 0.05 13.6 6.4 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FPN1 PF06963.12 EAX82851.1 - 0.32 9.5 0.2 0.43 9.1 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) BATS PF06968.13 EAX82852.1 - 0.17 12.0 0.0 2.4 8.4 0.0 2.2 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain DUF3839 PF12943.7 EAX82853.1 - 1.1e-157 522.7 13.1 1.4e-157 522.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX82853.1 - 0.099 13.1 1.6 0.43 11.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX82853.1 - 0.13 12.8 6.4 0.81 10.2 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82853.1 - 0.73 10.4 4.8 0.51 10.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5446 PF17522.2 EAX82854.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF3839 PF12943.7 EAX82855.1 - 1.5e-155 515.7 13.5 2.1e-155 515.3 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82855.1 - 0.21 11.9 5.1 1.3 9.3 0.0 3.5 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82855.1 - 2 8.9 9.4 2 8.9 0.4 3.3 3 2 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX82856.1 - 1.3e-34 118.4 0.2 1.3e-34 118.4 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82856.1 - 0.0055 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX82856.1 - 0.55 10.7 6.9 4.9 7.7 1.7 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3781 PF12636.7 EAX82857.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Meiosis_expr PF15163.6 EAX82858.1 - 0.065 13.9 0.8 0.1 13.3 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX82858.1 - 0.17 11.7 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated DUF4107 PF13389.6 EAX82860.1 - 1.2e-71 240.1 3.1 1.9e-71 239.5 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX82861.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Asp_protease PF09668.10 EAX82862.1 - 0.0013 18.5 20.4 22 4.9 0.3 7.8 1 1 8 9 9 9 7 Aspartyl protease DUF1993 PF09351.10 EAX82862.1 - 0.0025 18.0 32.3 23 5.1 0.2 8.0 1 1 7 8 8 8 8 Domain of unknown function (DUF1993) DUF3839 PF12943.7 EAX82863.1 - 3e-109 364.1 6.2 1.1e-108 362.3 6.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Glyco_transf_36 PF06165.11 EAX82864.1 - 0.00084 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 36 Meiosis_expr PF15163.6 EAX82865.1 - 0.029 15.0 1.7 0.033 14.9 0.8 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX82865.1 - 0.47 10.4 7.9 0.18 11.7 2.9 2.7 3 1 0 3 3 3 0 Spo12 family UBX PF00789.20 EAX82866.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Lar_restr_allev PF14354.6 EAX82866.1 - 0.12 12.8 0.2 0.32 11.4 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar PA26 PF04636.13 EAX82866.1 - 0.12 11.3 2.4 0.15 10.9 2.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3292 PF11696.8 EAX82866.1 - 1 7.7 8.5 1.1 7.5 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RR_TM4-6 PF06459.12 EAX82866.1 - 2 8.1 12.2 2.8 7.7 12.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 EAX82866.1 - 8.2 5.9 7.4 10 5.5 7.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 EAX82866.1 - 8.4 6.4 6.3 10 6.1 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 EAX82869.1 - 1.8e-37 129.1 0.0 3.1e-37 128.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX82869.1 - 3e-24 85.7 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX82869.1 - 4e-05 23.7 0.1 6.3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX82869.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX82869.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAX82869.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX82869.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GSHPx PF00255.19 EAX82870.1 - 1.3e-44 150.1 1.0 1.7e-44 149.8 1.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EAX82870.1 - 3.5e-05 23.7 0.1 4.8e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAX82870.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.4 1 1 0 1 1 1 1 Redoxin DUF3839 PF12943.7 EAX82871.1 - 3.5e-153 508.0 12.6 4.4e-153 507.7 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX82871.1 - 0.031 13.9 1.8 0.076 12.7 0.2 2.4 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit Fez1 PF06818.15 EAX82871.1 - 0.078 13.4 1.2 0.13 12.7 0.2 1.7 2 0 0 2 2 2 0 Fez1 Pox_A32 PF04665.12 EAX82872.1 - 1.3e-07 31.3 0.2 1.5e-07 31.2 0.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX82872.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX82872.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX82872.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX82872.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein T5orf172 PF10544.9 EAX82873.1 - 1.8e-06 28.4 0.1 3.7e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82874.1 - 8.1e-36 122.3 0.3 8.1e-36 122.3 0.3 1.9 2 1 1 3 3 3 1 KilA-N domain Cep57_MT_bd PF06657.13 EAX82874.1 - 0.011 16.1 5.5 0.59 10.6 1.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ApoL PF05461.11 EAX82874.1 - 2.4 7.4 6.3 2.4 7.4 0.4 2.1 2 0 0 2 2 2 0 Apolipoprotein L RabGAP-TBC PF00566.18 EAX82876.1 - 1.6e-13 50.8 3.1 2.1e-13 50.4 3.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Oxysterol_BP PF01237.18 EAX82877.1 - 1.2e-47 162.6 2.9 1.6e-46 158.9 2.9 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3839 PF12943.7 EAX82878.1 - 9.8e-155 513.1 13.3 1.3e-154 512.7 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX82878.1 - 0.2 12.2 3.8 1.7 9.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82878.1 - 5.4 7.5 8.3 1.9 9.0 1.0 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX82879.1 - 7.1e-07 29.7 0.5 2.4e-06 28.0 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX82879.1 - 0.086 12.7 1.1 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX82879.1 - 0.16 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3482 PF11981.8 EAX82880.1 - 0.037 13.4 0.4 0.037 13.4 0.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) E1_dh PF00676.20 EAX82880.1 - 0.08 11.9 2.8 0.19 10.7 0.5 2.0 2 0 0 2 2 2 0 Dehydrogenase E1 component KilA-N PF04383.13 EAX82881.1 - 4.9e-43 145.5 0.0 8.8e-43 144.7 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX82881.1 - 0.006 17.2 0.1 0.014 16.1 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family DUF3447 PF11929.8 EAX82882.1 - 2e-07 30.9 0.1 2e-07 30.9 0.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) ATP13 PF12921.7 EAX82882.1 - 0.054 13.4 2.4 0.14 12.0 1.4 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase expression DUF3839 PF12943.7 EAX82883.1 - 1.2e-153 509.5 12.8 1.5e-153 509.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX82883.1 - 0.44 11.5 2.2 0.72 10.9 0.5 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX82883.1 - 1.8 9.1 7.5 0.69 10.4 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82883.1 - 2.3 8.8 5.3 2.3 8.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DDR PF08841.10 EAX82884.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX82884.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Pox_D5 PF03288.16 EAX82886.1 - 2.7e-05 24.6 2.8 0.00017 22.0 2.8 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX82886.1 - 0.011 16.3 0.1 0.024 15.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX82886.1 - 0.027 14.4 0.2 0.065 13.2 0.2 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX82887.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX82889.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82889.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82889.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82889.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX82893.1 - 1.1e-154 512.9 13.0 1.3e-154 512.6 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82893.1 - 0.18 11.2 3.5 0.14 11.6 0.7 1.9 1 1 0 2 2 2 0 Z1 domain DUF2408 PF10303.9 EAX82893.1 - 2.3 8.8 5.3 2.8 8.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX82893.1 - 4.1 7.9 9.6 0.89 10.1 1.4 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ResIII PF04851.15 EAX82894.1 - 1.8e-05 24.8 0.5 2.9e-05 24.1 0.5 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82894.1 - 0.00028 20.7 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX82894.1 - 0.00043 20.6 0.0 0.00062 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX82894.1 - 0.0019 18.0 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82894.1 - 0.0067 16.8 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82894.1 - 0.032 13.7 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX82894.1 - 0.057 13.2 0.0 0.08 12.7 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein SWI2_SNF2 PF18766.1 EAX82894.1 - 0.085 12.5 0.3 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX82894.1 - 0.091 12.3 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX82894.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX82894.1 - 0.27 10.8 2.4 0.13 11.8 0.5 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase KilA-N PF04383.13 EAX82895.1 - 4.2e-08 33.0 0.1 6.4e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 KilA-N domain DDR PF08841.10 EAX82900.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX82901.1 - 8.2e-07 28.7 2.1 8.2e-07 28.7 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82901.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82901.1 - 5.5e-05 23.0 0.3 0.54 10.0 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82901.1 - 0.00014 22.0 3.1 0.00032 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82901.1 - 0.00061 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX82901.1 - 0.00088 19.0 0.4 0.0063 16.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX82901.1 - 0.0013 18.6 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82901.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX82901.1 - 0.032 13.8 0.1 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX82901.1 - 0.065 12.8 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX82901.1 - 0.076 13.4 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX82901.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX82901.1 - 0.17 12.3 3.1 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX82901.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX82902.1 - 3.4e-44 149.3 0.2 8.5e-44 148.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82902.1 - 0.0089 16.6 0.1 0.031 14.9 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family DUF3839 PF12943.7 EAX82903.1 - 7.6e-142 470.9 10.5 1e-141 470.5 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82903.1 - 0.079 13.4 2.6 4.5 7.8 0.1 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82903.1 - 1.1 9.8 5.3 0.3 11.6 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX82903.1 - 4.1 7.8 6.9 13 6.2 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal Trypan_PARP PF05887.11 EAX82904.1 - 0.081 12.9 11.3 0.13 12.3 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX82905.1 - 0.047 14.1 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TMP PF05017.14 EAX82910.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX82911.1 - 0.065 13.1 0.7 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX82913.1 - 1.6e-24 86.7 2.8 5.8e-20 71.8 1.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX82913.1 - 1.1e-12 47.8 1.3 4.4e-11 42.6 0.2 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_A32 PF04665.12 EAX82915.1 - 2.7e-06 27.0 2.8 2.7e-06 27.0 2.8 1.8 1 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82915.1 - 1.2e-05 25.1 0.3 0.17 11.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82915.1 - 3.7e-05 24.0 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82915.1 - 0.00015 21.8 2.9 0.00029 20.9 2.8 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82915.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82915.1 - 0.0008 19.3 0.6 0.0016 18.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82915.1 - 0.0022 17.7 0.6 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82915.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82915.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82915.1 - 0.12 12.8 0.1 0.77 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX82915.1 - 0.14 11.8 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX82915.1 - 0.48 10.7 3.6 16 5.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX82916.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) GGDEF PF00990.21 EAX82917.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX82917.1 - 0.099 12.9 8.1 0.15 12.3 8.1 1.3 1 1 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX82918.1 - 7.3e-57 191.3 6.8 8.1e-57 191.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX82919.1 - 2.1e-06 28.2 0.2 4.2e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX82920.1 - 6.5e-34 116.1 1.1 9.8e-34 115.6 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX82921.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82921.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82921.1 - 5.3e-05 23.0 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82921.1 - 0.00018 21.6 3.8 0.00044 20.3 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82921.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82921.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82921.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82921.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82921.1 - 0.071 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82921.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82921.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82921.1 - 0.22 11.8 4.8 3.3 8.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX82924.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX82925.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Collagen_bind_2 PF12904.7 EAX82926.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase GPS2_interact PF15784.5 EAX82927.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82927.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX82931.1 - 1.4e-07 31.3 1.3 1.5e-07 31.1 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82931.1 - 0.0036 17.0 0.1 0.0041 16.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX82931.1 - 0.0047 15.8 0.1 0.0064 15.4 0.1 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX82931.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein YtxH PF12732.7 EAX82932.1 - 0.081 13.5 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 YtxH-like protein DUF3839 PF12943.7 EAX82933.1 - 9.2e-156 516.4 13.7 1.1e-155 516.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82933.1 - 0.17 11.7 1.7 0.47 10.3 0.5 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX82933.1 - 0.44 10.9 2.9 0.89 9.9 1.1 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX82933.1 - 1 9.8 6.5 5 7.7 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX82934.1 - 1.7e-28 100.2 16.9 2.1e-28 99.9 16.9 1.0 1 0 0 1 1 1 1 Glycine rich protein BACK PF07707.15 EAX82935.1 - 0.00056 20.0 1.3 0.001 19.2 1.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF2400 PF09674.10 EAX82935.1 - 0.14 12.1 1.2 16 5.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) GP17 PF17420.2 EAX82935.1 - 0.3 11.3 6.0 2 8.6 0.1 3.0 1 1 2 3 3 3 0 Superinfection exclusion gene product 17 DUF4107 PF13389.6 EAX82936.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX82939.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX82940.1 - 0.075 13.6 4.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX82941.1 - 0.026 15.0 0.9 0.045 14.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX82942.1 - 2.3e-158 525.0 14.1 2.8e-158 524.7 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82942.1 - 1.4 9.4 7.6 1.5 9.3 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX82944.1 - 0.011 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX82945.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX82945.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Ank_4 PF13637.6 EAX82947.1 - 5.3e-28 97.0 1.8 7.5e-13 48.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX82947.1 - 4.5e-25 86.9 4.8 5.7e-07 29.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAX82947.1 - 4.1e-23 81.8 2.8 1.2e-11 45.0 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX82947.1 - 7.4e-21 72.0 1.4 7.5e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX82947.1 - 4.7e-20 71.4 0.5 1.1e-09 38.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX82947.1 - 0.00025 20.8 0.6 0.016 14.9 0.1 2.4 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like Arg_repressor PF01316.21 EAX82947.1 - 0.014 15.1 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain BING4CT PF08149.11 EAX82947.1 - 0.047 13.5 0.1 0.89 9.4 0.0 2.5 1 1 1 2 2 2 0 BING4CT (NUC141) domain DUF3839 PF12943.7 EAX82949.1 - 7.8e-39 133.6 4.0 1.1e-38 133.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX82949.1 - 0.17 12.4 0.9 0.79 10.2 0.1 2.2 3 0 0 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX82949.1 - 0.41 11.1 2.1 1.7 9.0 1.0 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain KilA-N PF04383.13 EAX82950.1 - 2.7e-32 110.9 0.0 3.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain Ank_2 PF12796.7 EAX82951.1 - 4.6e-54 181.0 3.3 1.7e-19 70.2 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82951.1 - 3.5e-43 145.5 1.7 1.1e-08 35.4 0.1 7.1 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX82951.1 - 8.6e-42 139.8 0.7 8.2e-05 22.9 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX82951.1 - 7.6e-41 137.7 7.8 1.9e-07 31.2 0.0 8.2 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82951.1 - 8e-38 124.1 5.4 0.0017 18.6 0.0 9.0 9 1 0 9 9 9 8 Ankyrin repeat DBD_Tnp_Hermes PF10683.9 EAX82951.1 - 0.0031 17.2 0.0 12 5.6 0.0 4.5 4 1 1 5 5 5 1 Hermes transposase DNA-binding domain DUF3839 PF12943.7 EAX82953.1 - 6.7e-157 520.1 12.5 8.5e-157 519.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX82953.1 - 0.13 12.1 0.8 0.36 10.7 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX82953.1 - 0.31 11.5 2.7 5.4 7.5 0.2 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82954.1 - 1e-153 509.7 12.0 1.3e-153 509.4 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX82954.1 - 0.19 12.2 3.0 11 6.6 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX82954.1 - 0.86 10.2 3.5 0.7 10.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Ank_2 PF12796.7 EAX82955.1 - 1.7e-73 243.3 27.6 1e-16 61.3 0.4 6.5 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX82955.1 - 3.6e-53 177.3 13.6 6.5e-13 48.9 0.0 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX82955.1 - 6.4e-49 158.2 24.5 1.1e-05 25.3 0.0 11.5 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EAX82955.1 - 5e-46 154.2 15.7 7.6e-12 45.2 0.1 9.7 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX82955.1 - 1.2e-44 148.8 15.1 0.00014 22.1 0.0 10.7 10 0 0 10 10 10 9 Ankyrin repeat DUF3447 PF11929.8 EAX82955.1 - 1.3e-05 25.0 21.7 0.00056 19.8 0.2 6.1 4 2 2 7 7 7 2 Domain of unknown function (DUF3447) Meiosis_expr PF15163.6 EAX82956.1 - 0.068 13.9 0.8 0.11 13.2 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX82956.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated DUF4108 PF13390.6 EAX82959.1 - 3e-57 192.6 6.7 3.4e-57 192.4 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX82960.1 - 5.5e-05 23.6 3.2 0.00035 21.0 3.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like MA3 PF02847.17 EAX82962.1 - 0.027 14.5 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 MA3 domain Spore_III_AE PF09546.10 EAX82962.1 - 0.038 13.2 0.6 0.038 13.2 0.6 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) DNA_repr_REX1B PF14966.6 EAX82962.1 - 0.052 14.2 0.3 1.3 9.7 0.2 2.0 1 1 1 2 2 2 0 DNA repair REX1-B GPS2_interact PF15784.5 EAX82964.1 - 0.061 13.8 1.1 0.08 13.4 1.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX82964.1 - 0.068 12.1 0.1 0.068 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX82965.1 - 0.081 12.9 7.2 0.12 12.3 7.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX82966.1 - 4.6e-23 81.2 0.3 1.5e-22 79.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX82967.1 - 8.3e-38 128.7 0.1 8.3e-38 128.7 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX82967.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX82967.1 - 0.35 9.4 0.2 0.44 9.0 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Methyltransf_11 PF08241.12 EAX82968.1 - 3.6e-13 50.0 0.0 5.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX82968.1 - 3.8e-11 43.5 0.0 6.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX82968.1 - 8.8e-07 28.9 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX82968.1 - 1.1e-06 28.5 0.1 2.1e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX82968.1 - 2.9e-06 27.9 0.1 6.6e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAX82968.1 - 0.00085 19.2 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 EAX82968.1 - 0.073 12.4 0.2 0.83 8.9 0.2 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 EAX82968.1 - 0.097 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 EAX82968.1 - 0.13 11.7 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Ras PF00071.22 EAX82969.1 - 2.4e-53 180.1 0.3 2.9e-53 179.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX82969.1 - 1.4e-30 106.0 0.2 3.1e-30 104.9 0.1 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX82969.1 - 3.9e-14 52.5 0.1 4.9e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX82969.1 - 2.8e-08 33.8 0.1 4.7e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX82969.1 - 6.9e-05 22.5 0.2 0.003 17.1 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX82969.1 - 8.6e-05 22.0 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 EAX82969.1 - 0.00048 19.5 0.1 0.00081 18.8 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EAX82969.1 - 0.00069 19.9 0.1 0.0024 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAX82969.1 - 0.00076 19.0 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAX82969.1 - 0.0011 18.8 0.3 0.17 11.8 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 EAX82969.1 - 0.0029 16.8 1.5 0.63 9.1 0.1 3.0 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 EAX82969.1 - 0.0036 16.8 0.0 0.006 16.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EAX82969.1 - 0.0039 16.8 0.1 0.045 13.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EAX82969.1 - 0.0045 16.9 0.1 0.0094 15.9 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.6 EAX82969.1 - 0.0068 16.8 0.1 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EAX82969.1 - 0.0085 15.8 0.1 0.072 12.8 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 EAX82969.1 - 0.0089 15.8 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 EAX82969.1 - 0.01 15.3 0.1 0.019 14.5 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 EAX82969.1 - 0.011 16.2 0.1 0.048 14.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAX82969.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 EAX82969.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EAX82969.1 - 0.017 14.9 0.1 3.2 7.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EAX82969.1 - 0.018 15.4 0.1 0.26 11.7 0.1 2.3 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EAX82969.1 - 0.028 14.9 0.5 0.034 14.7 0.5 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EAX82969.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EAX82969.1 - 0.061 13.0 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.6 EAX82969.1 - 0.064 12.0 0.1 1 8.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EAX82969.1 - 0.069 13.7 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX82969.1 - 0.076 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAX82969.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ig_3 PF13927.6 EAX82969.1 - 0.086 13.4 0.0 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain AAA_5 PF07728.14 EAX82969.1 - 0.09 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EAX82969.1 - 0.091 12.8 0.8 0.22 11.6 0.8 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 EAX82969.1 - 0.14 11.3 0.5 0.44 9.7 0.2 1.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EAX82969.1 - 0.16 11.7 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAX82969.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EAX82969.1 - 0.16 12.2 0.2 0.39 11.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain T5orf172 PF10544.9 EAX82970.1 - 1e-06 29.2 0.3 1.8e-06 28.4 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX82971.1 - 6.1e-07 29.2 2.0 6.1e-07 29.2 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX82971.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX82971.1 - 6e-05 23.3 0.1 0.00039 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX82971.1 - 9.8e-05 22.4 3.3 0.00023 21.2 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82971.1 - 0.00056 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX82971.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX82971.1 - 0.0022 17.8 0.5 0.0042 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82971.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX82971.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82971.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82971.1 - 0.14 12.6 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82971.1 - 0.28 11.4 3.8 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX82972.1 - 0.14 12.0 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF2897 PF11446.8 EAX82975.1 - 1.1 9.1 3.8 2.4 8.1 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) KilA-N PF04383.13 EAX82976.1 - 3.8e-10 39.6 0.1 9e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain NTS PF15447.6 EAX82976.1 - 0.18 12.3 3.3 2.3 8.8 0.9 2.6 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 KilA-N PF04383.13 EAX82978.1 - 1.8e-34 118.0 0.6 3.4e-34 117.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX82979.1 - 9.5e-07 28.5 2.0 9.5e-07 28.5 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82979.1 - 3.4e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82979.1 - 4.2e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82979.1 - 0.00015 21.8 3.3 0.00035 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82979.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX82979.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX82979.1 - 0.0021 17.9 0.9 0.0086 15.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82979.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX82979.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82979.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82979.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX82979.1 - 0.24 11.8 3.2 0.73 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX82979.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3328 PF11807.8 EAX82980.1 - 0.021 14.6 0.2 0.041 13.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) OAD_gamma PF04277.13 EAX82980.1 - 0.049 14.2 0.5 0.11 13.1 0.5 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain C-C_Bond_Lyase PF15617.6 EAX82980.1 - 0.074 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold UPF0203 PF05254.12 EAX82980.1 - 0.1 12.9 2.0 3 8.1 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Orf78 PF06024.12 EAX82980.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) ETRAMP PF09716.10 EAX82980.1 - 0.11 12.6 0.3 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3149 PF11346.8 EAX82980.1 - 0.11 12.1 3.2 0.1 12.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF4108 PF13390.6 EAX82981.1 - 6e-42 143.0 3.1 6.5e-42 142.9 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX82981.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein GGDEF PF00990.21 EAX82982.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX82983.1 - 5.2e-07 29.4 2.3 5.2e-07 29.4 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX82983.1 - 5.6e-05 23.4 0.2 0.00037 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX82983.1 - 6.3e-05 22.8 0.2 0.34 10.6 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX82983.1 - 0.00011 22.3 3.1 0.00026 21.1 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82983.1 - 0.00054 19.8 0.1 0.00096 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX82983.1 - 0.0021 17.9 0.5 0.0052 16.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX82983.1 - 0.0026 17.5 0.5 0.018 14.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX82983.1 - 0.013 15.9 0.0 0.029 14.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX82983.1 - 0.062 12.8 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX82983.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX82983.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX82983.1 - 0.14 12.6 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX82983.1 - 0.4 11.0 3.5 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX82984.1 - 8.7e-158 523.1 13.3 1.1e-157 522.7 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX82984.1 - 0.11 12.8 0.2 2.3 8.6 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82984.1 - 0.33 11.4 6.4 2.4 8.7 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82986.1 - 5.8e-86 287.9 5.4 7e-86 287.6 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FNIP_M PF14637.6 EAX82988.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain GGDEF PF00990.21 EAX82991.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX82991.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX82991.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX82992.1 - 4.7e-05 23.4 0.1 6.1e-05 23.1 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX82992.1 - 0.00028 20.7 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX82992.1 - 0.001 19.4 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX82992.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX82992.1 - 0.0035 17.7 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX82992.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX82992.1 - 0.062 12.9 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX82992.1 - 0.07 12.9 0.0 0.085 12.6 0.0 1.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 EAX82992.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAX82992.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX82993.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX82993.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX82993.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX82993.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX82994.1 - 3.6e-35 120.2 1.0 6.2e-35 119.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX82994.1 - 0.026 15.1 0.0 0.075 13.7 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX82995.1 - 2.3e-07 31.3 0.3 4.8e-07 30.3 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX82995.1 - 0.13 12.9 0.4 0.36 11.5 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 NYD-SP28 PF14772.6 EAX82996.1 - 3.7e-07 30.1 7.3 3.7e-07 30.1 7.3 5.4 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 EAX82996.1 - 3e-06 27.3 2.3 3e-06 27.3 2.3 3.3 4 0 0 4 4 4 1 Sperm tail C-terminal domain GTP_cyclohydroI PF01227.22 EAX82996.1 - 0.04 13.3 0.4 0.04 13.3 0.4 2.5 2 1 1 3 3 3 0 GTP cyclohydrolase I TrbI_Ftype PF09677.10 EAX82996.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.5 3 1 0 4 4 4 0 Type-F conjugative transfer system protein (TrbI_Ftype) HALZ PF02183.18 EAX82996.1 - 1.2 9.4 15.5 0.88 9.8 1.6 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Phe_tRNA-synt_N PF02912.18 EAX82996.1 - 5.7 7.0 13.2 4.3 7.4 0.6 4.2 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain T3SS_needle_F PF09392.10 EAX82996.1 - 7 6.9 17.7 35 4.7 0.0 5.5 4 2 1 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3839 PF12943.7 EAX82997.1 - 7.1e-147 487.3 11.9 1e-146 486.8 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX82997.1 - 0.011 16.3 0.1 0.074 13.6 0.2 2.4 2 0 0 2 2 2 0 T5orf172 domain Rx_N PF18052.1 EAX82997.1 - 0.079 13.2 0.8 1.7 9.0 0.1 2.8 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX82997.1 - 0.44 11.0 2.6 3 8.4 0.3 2.8 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX82998.1 - 5.2e-81 271.7 6.8 6.2e-81 271.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX82998.1 - 0.015 14.8 0.4 0.017 14.7 0.4 1.1 1 0 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX82998.1 - 0.094 13.2 1.2 0.33 11.5 1.2 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX82999.1 - 0.085 12.7 0.8 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83000.1 - 0.099 13.3 3.8 14 6.9 0.1 3.3 3 0 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAX83001.1 - 0.1 12.8 0.2 22 5.3 0.1 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain PapD_N PF00345.20 EAX83002.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX83002.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Trypan_PARP PF05887.11 EAX83005.1 - 0.032 14.2 10.1 0.037 14.0 10.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83005.1 - 3 8.3 4.7 3.6 8.0 4.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX83006.1 - 0.097 13.1 1.3 0.13 12.7 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TMP PF05017.14 EAX83008.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83009.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAX83010.1 - 1.1e-41 141.2 0.5 2.2e-41 140.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83010.1 - 0.011 16.4 0.1 0.03 15.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX83011.1 - 5.3e-156 517.2 11.5 6.7e-156 516.9 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83011.1 - 0.028 14.9 2.0 0.064 13.7 0.4 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX83011.1 - 0.12 12.9 3.9 0.26 11.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83011.1 - 0.62 10.6 5.6 4.4 7.8 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2897 PF11446.8 EAX83012.1 - 0.28 11.1 3.0 0.4 10.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX83013.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX83014.1 - 4.8e-153 507.5 11.7 6e-153 507.2 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX83014.1 - 0.05 13.3 2.1 0.61 9.8 0.5 2.7 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX83014.1 - 0.11 12.8 1.0 0.43 10.9 0.2 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit APC_u14 PF16635.5 EAX83014.1 - 1.7 9.2 4.3 1.5 9.4 2.3 1.9 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KilA-N PF04383.13 EAX83015.1 - 4.3e-17 62.0 0.3 8.7e-17 61.0 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain COPIIcoated_ERV PF07970.12 EAX83017.1 - 5.1e-41 140.9 0.4 7.5e-41 140.4 0.4 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX83017.1 - 2.9e-08 33.9 0.8 6e-07 29.7 0.5 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OAD_gamma PF04277.13 EAX83017.1 - 0.035 14.7 0.6 0.085 13.5 0.6 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Toxin_R_bind_C PF07951.12 EAX83019.1 - 0.026 14.2 4.0 0.077 12.6 0.5 2.6 2 1 1 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding Herpes_IE2_3 PF03361.14 EAX83019.1 - 0.028 14.3 1.1 0.63 9.9 0.2 2.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX83019.1 - 0.54 10.6 8.2 2.3 8.6 0.9 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region Trypan_PARP PF05887.11 EAX83020.1 - 0.037 14.0 11.1 0.052 13.5 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX83021.1 - 0.036 14.5 0.6 0.05 14.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83021.1 - 0.93 9.5 4.8 1 9.3 4.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX83022.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX83022.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX83023.1 - 1.4e-30 106.6 11.8 7.4e-30 104.2 11.8 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX83024.1 - 4e-157 520.9 13.2 5e-157 520.6 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83024.1 - 0.032 14.7 2.3 0.12 12.8 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83024.1 - 0.41 11.1 7.0 2.1 8.9 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83024.1 - 0.52 10.9 6.7 0.18 12.4 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX83025.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX83026.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX83027.1 - 3.3e-60 203.5 3.9 3.7e-60 203.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX83029.1 - 4.6e-155 514.1 13.3 5.9e-155 513.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2730 PF10805.8 EAX83029.1 - 0.03 14.4 3.6 6.8 6.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 EAX83029.1 - 0.033 14.6 2.7 0.099 13.1 0.4 2.1 2 0 0 2 2 2 0 Fez1 DUF5398 PF17376.2 EAX83029.1 - 0.37 11.5 0.1 0.37 11.5 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX83029.1 - 1 9.8 8.1 1.9 9.0 0.8 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83029.1 - 3.9 8.0 7.3 0.4 11.2 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX83030.1 - 5.6e-157 520.4 15.4 7e-157 520.1 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX83030.1 - 0.079 12.5 0.1 0.42 10.1 0.1 2.2 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX83030.1 - 1.2 9.7 8.6 1.9 9.0 1.0 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83031.1 - 2.1e-06 28.2 0.2 5.1e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83031.1 - 0.0076 16.1 0.1 0.055 13.3 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Styelin PF17562.2 EAX83032.1 - 0.0014 19.0 0.9 0.0023 18.3 0.9 1.4 1 0 0 1 1 1 1 Styelin dsDNA_bind PF01984.20 EAX83032.1 - 0.025 14.8 0.4 0.036 14.3 0.4 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain T5orf172 PF10544.9 EAX83034.1 - 7.9e-07 29.6 0.2 1.9e-06 28.3 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83034.1 - 0.0085 15.9 0.3 0.051 13.4 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX83034.1 - 0.019 14.5 0.7 0.21 11.1 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83035.1 - 3e-42 143.0 1.6 3.6e-42 142.7 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83035.1 - 0.0074 16.9 0.8 0.022 15.4 0.0 2.1 3 0 0 3 3 3 1 Parathyroid hormone family DUF3653 PF12375.8 EAX83036.1 - 0.1 12.7 0.3 3.3 7.9 0.0 2.6 2 1 1 3 3 3 0 Phage protein Pox_A32 PF04665.12 EAX83037.1 - 9.3e-07 28.5 1.9 9.3e-07 28.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83037.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83037.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83037.1 - 0.00019 21.5 3.6 0.00045 20.3 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83037.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83037.1 - 0.0017 18.2 0.6 0.0044 16.8 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83037.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83037.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX83037.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX83037.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83037.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX83037.1 - 0.25 11.8 3.2 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX83037.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX83038.1 - 0.023 15.2 0.9 0.041 14.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX83039.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83041.1 - 1.7e-05 24.4 1.7 1.7e-05 24.4 1.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83041.1 - 3.3e-05 23.7 0.3 0.28 10.9 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83041.1 - 3.6e-05 24.1 0.2 0.00026 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83041.1 - 0.00016 21.7 3.9 0.00042 20.4 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83041.1 - 0.00038 20.3 0.1 0.001 18.9 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX83041.1 - 0.0016 18.1 0.5 0.01 15.5 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX83041.1 - 0.0018 18.2 0.4 0.0044 16.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83041.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83041.1 - 0.053 13.9 0.0 1 9.8 0.0 2.3 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX83041.1 - 0.065 12.8 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX83041.1 - 0.07 12.6 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Elong_Iki1 PF10483.9 EAX83041.1 - 0.077 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX83041.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83041.1 - 0.22 11.5 2.0 1.6 8.8 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) Trypan_PARP PF05887.11 EAX83042.1 - 0.0083 16.1 6.0 0.013 15.5 6.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX83044.1 - 3.4e-49 164.7 35.3 5.4e-23 80.8 5.8 4.7 3 2 1 4 4 4 3 Phage tail repeat like DUF480 PF04337.12 EAX83044.1 - 0.023 14.8 0.0 0.058 13.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF480 DUF4116 PF13475.6 EAX83044.1 - 0.03 14.1 0.9 0.072 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Mcm10 PF09332.11 EAX83044.1 - 1.2 8.5 14.5 0.81 9.1 9.8 2.1 2 0 0 2 2 2 0 Mcm10 replication factor PH_TFIIH PF08567.11 EAX83044.1 - 2.2 8.6 9.2 21 5.5 0.1 4.3 3 2 2 5 5 5 0 TFIIH p62 subunit, N-terminal domain SAS4 PF15460.6 EAX83044.1 - 3.3 7.9 16.5 14 5.9 5.3 3.4 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 TMP PF05017.14 EAX83046.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83047.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX83048.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83049.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DDE_Tnp_4 PF13359.6 EAX83050.1 - 3.9e-36 124.1 0.0 9.1e-36 122.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX83050.1 - 1.2e-13 51.1 1.2 3.3e-13 49.7 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAX83050.1 - 8.4e-07 28.8 0.5 9.2e-06 25.4 0.5 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX83050.1 - 0.00018 21.2 0.8 0.0031 17.2 0.5 2.4 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease UCH_1 PF13423.6 EAX83050.1 - 0.002 17.8 2.5 0.011 15.4 1.0 2.4 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX83050.1 - 0.018 14.5 0.6 0.57 9.6 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH PF00443.29 EAX83051.1 - 0.0085 15.6 2.5 0.061 12.8 1.6 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX83051.1 - 0.26 10.8 2.6 0.68 9.5 0.8 2.3 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF3839 PF12943.7 EAX83052.1 - 2.9e-155 514.8 12.7 3.5e-155 514.5 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83052.1 - 1 9.9 4.2 5.1 7.6 0.1 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83052.1 - 1.4 9.5 4.4 0.97 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX83053.1 - 1.2e-06 28.2 0.7 1.4e-06 28.0 0.7 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83053.1 - 0.0049 16.6 0.1 0.012 15.3 0.0 1.6 1 1 1 2 2 2 1 IstB-like ATP binding protein Epimerase_2 PF02350.19 EAX83053.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Tetraspanin PF00335.20 EAX83054.1 - 1.4e-05 24.9 1.9 1.7e-05 24.6 1.9 1.2 1 0 0 1 1 1 1 Tetraspanin family PapD_N PF00345.20 EAX83055.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX83055.1 - 0.07 13.1 0.5 0.1 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX83056.1 - 6.3e-158 523.5 12.7 7.8e-158 523.2 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83056.1 - 0.096 13.1 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83056.1 - 0.32 11.5 4.6 2 8.9 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83057.1 - 1.5e-153 509.2 12.7 1.9e-153 508.8 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX83059.1 - 5.3e-33 114.5 1.9 7.7e-33 113.9 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX83060.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83061.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX83062.1 - 2.1e-157 521.8 11.7 2.7e-157 521.5 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX83062.1 - 0.92 9.9 5.2 13 6.2 0.0 3.8 3 1 1 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX83063.1 - 4.7e-14 52.2 0.1 4.7e-14 52.2 0.1 1.0 1 0 0 1 1 1 1 KilA-N domain Gly-zipper_Omp PF13488.6 EAX83064.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX83064.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX83064.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX83064.1 - 3 8.9 0.2 3 8.9 0.2 3.4 4 0 0 4 4 4 0 TMP repeat Myb_DNA-binding PF00249.31 EAX83065.1 - 5.5e-22 77.7 0.4 1.1e-11 44.7 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX83065.1 - 1e-16 60.9 2.8 8e-13 48.4 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX83065.1 - 0.0043 16.9 3.9 0.27 11.2 0.3 2.6 2 1 0 2 2 2 2 Myb DNA-binding like HEPN_RES_NTD1 PF18870.1 EAX83065.1 - 0.077 13.2 0.7 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 Myb_DNA-bind_4 PF13837.6 EAX83065.1 - 0.44 11.0 3.8 0.48 10.8 0.6 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PTR PF12789.7 EAX83066.1 - 1.3e-09 37.9 34.6 2.3e-08 34.0 6.0 5.1 6 0 0 6 6 6 3 Phage tail repeat like LIFR_D2 PF17971.1 EAX83066.1 - 0.0038 17.4 0.3 0.68 10.2 0.0 2.3 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain DUF1910 PF08928.10 EAX83066.1 - 0.031 14.3 0.3 4.7 7.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) EpuA PF11772.8 EAX83066.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF5082 PF16888.5 EAX83066.1 - 1.6 9.0 6.5 0.63 10.3 1.4 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF2939 PF11159.8 EAX83067.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX83067.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX83067.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX83067.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX83068.1 - 0.015 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF1340 PF07067.11 EAX83070.1 - 0.17 11.3 0.6 0.18 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Ank_4 PF13637.6 EAX83071.1 - 6.1e-15 55.4 0.3 1.4e-12 47.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX83071.1 - 1.2e-14 54.0 0.5 2.3e-06 27.8 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX83071.1 - 5.2e-14 52.6 1.8 9.5e-14 51.8 1.8 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX83071.1 - 1.2e-12 46.8 0.1 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX83071.1 - 2.1e-12 47.0 2.2 6.5e-07 29.5 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX83071.1 - 0.059 13.5 0.1 0.53 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3718) DUF3447 PF11929.8 EAX83072.1 - 2.7e-40 136.2 5.1 5.1e-40 135.3 5.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX83072.1 - 5.9e-07 30.0 0.1 0.00083 19.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83072.1 - 0.026 15.1 1.1 20 5.9 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83072.1 - 0.033 14.7 1.2 6.9 7.6 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeat NICE-3 PF07406.11 EAX83073.1 - 0.0054 16.7 0.5 0.011 15.8 0.5 1.5 1 0 0 1 1 1 1 NICE-3 protein SF3A3 PF16837.5 EAX83073.1 - 0.52 10.9 4.7 5.3 7.6 0.2 3.4 3 1 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF1493 PF07377.12 EAX83074.1 - 0.094 13.2 0.6 0.2 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX83075.1 - 9.9e-48 160.1 33.3 3.9e-23 81.3 5.7 5.8 6 1 1 7 7 7 3 Phage tail repeat like YmaF PF12788.7 EAX83075.1 - 0.019 15.5 22.2 1.9 9.1 0.6 4.9 3 2 0 3 3 3 0 YmaF family DUF4116 PF13475.6 EAX83075.1 - 0.037 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF5519 PF17648.1 EAX83075.1 - 0.17 11.7 1.5 0.61 10.0 0.1 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5519) DUF3839 PF12943.7 EAX83076.1 - 4.9e-154 510.8 13.8 6.3e-154 510.4 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83076.1 - 3.2 8.3 7.5 1.9 9.0 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX83077.1 - 3.7e-62 208.5 8.2 4.2e-62 208.3 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83079.1 - 5e-07 29.4 2.1 5e-07 29.4 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83079.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83079.1 - 5.1e-05 23.6 0.2 0.0004 20.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83079.1 - 8.9e-05 22.5 2.4 0.00021 21.3 2.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83079.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83079.1 - 0.0014 18.5 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83079.1 - 0.002 17.8 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83079.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83079.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83079.1 - 0.088 13.2 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83079.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83079.1 - 0.32 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83080.1 - 2e-25 89.7 4.4 2.8e-25 89.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX83082.1 - 1e-66 224.1 2.5 1.4e-66 223.7 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83082.1 - 0.11 12.8 0.6 0.16 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF2939 PF11159.8 EAX83085.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83085.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX83086.1 - 0.0079 16.2 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Collagen_bind_2 PF12904.7 EAX83087.1 - 0.11 12.5 0.0 4.5 7.3 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase PTR PF12789.7 EAX83088.1 - 9.3e-136 442.0 105.1 2.3e-30 104.4 14.4 7.6 2 2 5 7 7 7 6 Phage tail repeat like Peptidase_S66 PF02016.15 EAX83088.1 - 8.1e-07 29.2 9.4 47 4.1 0.0 8.9 1 1 8 9 9 9 0 LD-carboxypeptidase N-terminal domain VCX_VCY PF15231.6 EAX83088.1 - 1.4e-05 25.8 11.5 1.9 9.2 0.4 4.5 1 1 5 6 6 6 6 Variable charge X/Y family DUF4116 PF13475.6 EAX83088.1 - 0.074 12.8 0.6 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX83088.1 - 0.08 12.4 18.2 0.79 9.1 0.8 4.1 1 1 5 6 6 6 0 RRNA methyltransferase AviRa Mucin-like PF16058.5 EAX83088.1 - 0.24 11.5 1.5 23 5.1 0.2 2.6 1 1 1 2 2 2 0 Mucin-like PH_TFIIH PF08567.11 EAX83088.1 - 0.41 11.0 25.7 35 4.8 0.3 8.9 1 1 9 10 10 10 0 TFIIH p62 subunit, N-terminal domain DUF2785 PF10978.8 EAX83088.1 - 2.9 7.6 12.9 3.7 7.3 2.6 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2785) DUF3839 PF12943.7 EAX83089.1 - 7.3e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX83089.1 - 0.073 13.2 0.1 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers T5orf172 PF10544.9 EAX83090.1 - 3.5e-06 27.5 0.1 7.9e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83090.1 - 0.056 13.3 0.1 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX83091.1 - 3e-40 136.6 1.5 3.5e-40 136.3 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83091.1 - 0.0017 19.0 0.7 0.02 15.5 0.0 2.4 3 0 0 3 3 3 1 Parathyroid hormone family RRP36 PF06102.12 EAX83091.1 - 0.21 11.6 9.2 0.18 11.8 4.0 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 GGDEF PF00990.21 EAX83093.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX83093.1 - 0.082 13.2 7.7 0.12 12.6 7.7 1.3 1 1 0 1 1 1 0 PcfK-like protein AAA_11 PF13086.6 EAX83094.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX83094.1 - 0.0026 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83094.1 - 0.0037 17.6 0.0 0.0055 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83094.1 - 0.0052 16.8 0.0 0.0067 16.4 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX83094.1 - 0.02 14.4 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX83094.1 - 0.049 13.2 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX83094.1 - 0.081 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX83094.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX83094.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX83095.1 - 6.2e-07 29.1 2.6 6.2e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83095.1 - 1.7e-05 24.7 0.3 0.16 11.7 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83095.1 - 8.5e-05 22.8 0.2 0.00057 20.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83095.1 - 0.00018 21.5 4.0 0.0003 20.8 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83095.1 - 0.00043 20.1 0.1 0.00077 19.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83095.1 - 0.0012 18.8 0.7 0.0041 16.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83095.1 - 0.0021 17.7 0.5 0.016 14.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83095.1 - 0.03 14.7 0.0 0.087 13.2 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX83095.1 - 0.047 13.2 0.1 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX83095.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX83095.1 - 0.076 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX83095.1 - 0.084 12.4 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX83095.1 - 0.13 12.5 3.8 4.2 7.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX83097.1 - 3.5e-61 205.3 6.3 3.9e-61 205.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX83097.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF3839 PF12943.7 EAX83098.1 - 9e-143 473.9 12.0 1.1e-142 473.6 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83098.1 - 0.055 13.9 0.4 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83098.1 - 0.9 10.0 8.2 0.47 11.0 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAS_N PF17828.1 EAX83099.1 - 0.0086 16.1 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX83100.1 - 0.032 14.6 1.2 0.037 14.4 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83100.1 - 1.7 8.7 6.8 2 8.4 6.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX83100.1 - 1.7 7.6 3.8 1.8 7.5 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein PapD_N PF00345.20 EAX83101.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX83101.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX83102.1 - 2.9e-08 33.0 1.1 6.8e-08 31.8 0.5 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX83102.1 - 0.051 12.3 1.6 0.75 8.4 1.6 2.3 1 1 0 1 1 1 0 DNA polymerase family B Homeodomain PF00046.29 EAX83103.1 - 0.1 12.5 0.5 0.23 11.3 0.5 1.8 1 1 0 1 1 1 0 Homeodomain GPS2_interact PF15784.5 EAX83105.1 - 0.045 14.2 1.3 0.062 13.8 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83105.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83106.1 - 0.062 13.3 8.6 0.1 12.6 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) APP_amyloid PF10515.9 EAX83106.1 - 0.19 12.3 0.9 0.33 11.5 0.9 1.5 1 1 0 1 1 1 0 Beta-amyloid precursor protein C-terminus MGC-24 PF05283.11 EAX83106.1 - 8 6.9 6.8 12 6.4 6.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_A_exo1 PF01612.20 EAX83107.1 - 0.039 13.7 0.1 0.066 12.9 0.1 1.3 1 1 0 1 1 1 0 3'-5' exonuclease DUF3839 PF12943.7 EAX83108.1 - 1.2e-125 417.9 6.4 1.3e-125 417.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83108.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX83108.1 - 0.14 12.6 0.6 2.6 8.5 0.3 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX83108.1 - 0.47 10.8 3.7 1.6 9.1 0.1 2.9 2 1 0 2 2 2 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX83109.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX83109.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX83109.1 - 0.011 15.4 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX83109.1 - 0.048 13.6 0.4 0.46 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX83109.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein KilA-N PF04383.13 EAX83110.1 - 7.2e-42 141.8 0.4 1.6e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83110.1 - 0.013 16.1 0.1 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX83111.1 - 1e-06 29.2 0.1 2.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX83112.1 - 8.8e-80 267.6 10.0 1.1e-79 267.3 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TPR_MLP1_2 PF07926.12 EAX83113.1 - 0.0085 16.2 0.4 0.011 15.9 0.4 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX83113.1 - 0.042 13.7 0.1 0.057 13.2 0.1 1.3 1 1 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX83113.1 - 0.32 10.9 7.8 0.12 12.3 2.5 2.4 3 0 0 3 3 3 0 Spo12 family DOCK-C2 PF14429.6 EAX83114.1 - 8e-05 22.5 0.1 0.0003 20.7 0.1 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF2939 PF11159.8 EAX83115.1 - 0.016 15.6 0.4 0.022 15.2 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX83115.1 - 1.9 7.5 3.6 1.8 7.5 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX83115.1 - 3 7.8 7.1 3.1 7.8 7.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX83116.1 - 0.0081 16.2 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX83117.1 - 4.1e-71 238.4 4.0 5.4e-71 238.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX83118.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX83120.1 - 2.1e-70 237.0 5.7 2.7e-70 236.6 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX83120.1 - 0.019 15.0 0.6 2.1 8.3 0.0 2.3 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RFX_DNA_binding PF02257.15 EAX83121.1 - 0.00029 21.4 0.2 0.00057 20.4 0.2 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX83121.1 - 0.00076 19.9 1.8 0.0012 19.3 1.8 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX83121.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RinB PF06116.12 EAX83121.1 - 0.24 11.5 0.3 55 4.0 0.0 3.0 1 1 2 3 3 3 0 Transcriptional activator RinB NdhO PF11910.8 EAX83121.1 - 0.47 10.7 2.8 0.63 10.3 0.2 2.4 1 1 2 3 3 3 0 Cyanobacterial and plant NDH-1 subunit O DUF3839 PF12943.7 EAX83126.1 - 9.3e-119 395.3 8.2 1.1e-118 395.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) CHASE3 PF05227.13 EAX83128.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX83128.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) KilA-N PF04383.13 EAX83129.1 - 5.4e-32 110.0 0.2 1.4e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX83130.1 - 1.1e-06 29.1 0.1 2.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83131.1 - 7.1e-43 145.0 0.4 1.7e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83131.1 - 0.0074 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX83131.1 - 0.25 11.8 4.4 0.68 10.4 3.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3504 PF12012.8 EAX83133.1 - 7.3e-11 42.2 0.4 21 5.0 0.0 8.3 8 0 0 8 8 8 7 Domain of unknown function (DUF3504) DUF4107 PF13389.6 EAX83134.1 - 2.3e-73 245.7 4.4 2.8e-73 245.4 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX83134.1 - 0.17 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX83135.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX83136.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3519 PF12033.8 EAX83137.1 - 0.14 12.6 0.2 0.71 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) PSP PF04046.16 EAX83138.1 - 0.11 12.3 2.5 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX83139.1 - 3.3e-138 459.0 12.4 3.6e-138 458.8 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83139.1 - 0.061 13.8 2.6 1.1 9.7 0.9 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX83140.1 - 0.69 10.8 4.0 37 5.6 0.1 3.5 4 0 0 4 4 4 0 TMP repeat DUF3839 PF12943.7 EAX83141.1 - 5.1e-156 517.3 13.3 6.3e-156 517.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX83141.1 - 0.052 13.8 1.1 1.3 9.4 0.1 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX83141.1 - 0.44 11.0 5.3 5.3 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83141.1 - 1.5 9.4 5.5 0.93 10.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) ResIII PF04851.15 EAX83142.1 - 5.6e-05 23.2 2.6 0.00013 22.1 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX83142.1 - 0.00025 20.9 0.2 0.26 11.0 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83142.1 - 0.00026 21.3 0.1 0.0006 20.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX83142.1 - 0.00041 20.2 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83142.1 - 0.0012 18.7 0.6 0.0029 17.4 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83142.1 - 0.012 16.0 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX83142.1 - 0.012 15.0 3.4 0.01 15.3 1.5 2.1 1 1 1 2 2 2 0 Poxvirus A32 protein DUF4588 PF15251.6 EAX83142.1 - 0.048 13.4 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX83142.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX83142.1 - 0.091 12.3 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX83142.1 - 0.11 12.8 4.1 3.3 8.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX83142.1 - 0.82 10.1 5.4 0.19 12.1 1.0 2.2 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX83144.1 - 4.2e-59 198.6 4.4 4.6e-59 198.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX83144.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Amidase02_C PF12123.8 EAX83145.1 - 0.0025 17.5 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83146.1 - 7.3e-73 244.1 3.6 9.2e-73 243.7 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83146.1 - 0.098 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4870 PF09685.10 EAX83148.1 - 0.0069 16.5 0.9 0.01 16.0 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) Ycf66_N PF07444.11 EAX83148.1 - 0.028 14.5 1.3 0.047 13.8 1.3 1.3 1 0 0 1 1 1 0 Ycf66 protein N-terminus Sec34 PF04136.15 EAX83149.1 - 0.0013 18.6 1.4 0.0026 17.7 1.4 1.5 1 0 0 1 1 1 1 Sec34-like family DUF3839 PF12943.7 EAX83152.1 - 1.3e-156 519.2 12.5 1.6e-156 518.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83152.1 - 0.58 10.6 5.0 5 7.7 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX83154.1 - 0.27 12.0 5.7 22 6.3 0.5 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX83154.1 - 3.4 7.6 7.5 3.6 7.6 7.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX83155.1 - 0.0041 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX83155.1 - 0.16 11.8 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Imm70 PF15601.6 EAX83157.1 - 0.36 10.4 19.0 22 4.6 0.9 5.7 1 1 5 6 6 6 0 Immunity protein 70 DNA_pol_A_exo1 PF01612.20 EAX83157.1 - 0.83 9.3 10.9 8.7 6.0 0.2 3.1 1 1 1 2 2 2 0 3'-5' exonuclease GPS2_interact PF15784.5 EAX83158.1 - 0.045 14.2 0.7 0.062 13.7 0.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Sulfatase PF00884.23 EAX83159.1 - 6.8e-17 61.8 0.7 3.5e-16 59.5 0.7 2.0 1 1 0 1 1 1 1 Sulfatase Pox_A32 PF04665.12 EAX83160.1 - 1.5e-06 27.9 2.3 1.5e-06 27.9 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83160.1 - 3.8e-05 23.5 0.3 0.35 10.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83160.1 - 4.6e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83160.1 - 0.00032 20.8 4.2 0.00061 19.8 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83160.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83160.1 - 0.0021 17.9 1.0 0.0043 16.9 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83160.1 - 0.0059 16.3 2.8 0.014 15.0 0.4 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83160.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX83160.1 - 0.087 12.9 0.7 1.3 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX83160.1 - 0.09 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX83160.1 - 0.1 13.0 0.1 0.93 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83160.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83160.1 - 0.5 10.7 4.1 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2805 PF10985.8 EAX83160.1 - 0.85 10.0 0.0 0.85 10.0 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2805) DUF573 PF04504.14 EAX83160.1 - 1.7 9.3 11.7 0.34 11.6 1.7 3.5 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX83162.1 - 1.1e-120 401.5 11.7 1.4e-120 401.2 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83162.1 - 0.048 14.1 1.9 5.3 7.6 0.0 2.9 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX83162.1 - 0.092 12.6 1.7 0.25 11.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX83163.1 - 3e-39 133.3 0.4 8e-39 132.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83163.1 - 0.013 16.1 0.4 0.038 14.6 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family Gly_rich PF12810.7 EAX83165.1 - 2.4e-46 158.6 57.4 2.8e-46 158.4 57.4 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX83166.1 - 1.9e-78 263.3 10.3 2.5e-78 262.9 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Treslin_N PF15292.6 EAX83166.1 - 0.048 12.0 1.3 0.056 11.8 1.3 1.0 1 0 0 1 1 1 0 Treslin N-terminus NTP_transf_6 PF06042.11 EAX83166.1 - 0.12 12.2 1.1 0.51 10.2 1.1 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX83168.1 - 0.0023 17.6 0.0 0.0066 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX83168.1 - 0.18 11.6 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Pox_A32 PF04665.12 EAX83169.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX83169.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase KilA-N PF04383.13 EAX83170.1 - 1.6e-33 114.9 0.6 3.4e-33 113.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX83171.1 - 1.4e-156 519.1 14.1 1.8e-156 518.8 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83171.1 - 0.38 11.2 6.4 2.5 8.6 0.8 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83171.1 - 1.9 9.0 6.5 0.63 10.6 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX83172.1 - 9.8e-36 122.0 0.4 9.8e-36 122.0 0.4 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83172.1 - 0.0066 17.0 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX83173.1 - 1.3e-07 31.4 0.3 1.5e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX83173.1 - 0.0049 15.8 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Zot PF05707.12 EAX83173.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX83173.1 - 0.046 13.7 0.4 0.45 10.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX83173.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Coatomer_g_Cpla PF16381.5 EAX83174.1 - 3.8e-20 72.1 0.1 1.3e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 EAX83174.1 - 1.5e-19 70.7 0.9 3.8e-19 69.3 0.9 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain YqjK PF13997.6 EAX83175.1 - 0.059 13.6 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 YqjK-like protein HEAT_2 PF13646.6 EAX83176.1 - 0.0064 16.9 0.0 0.76 10.2 0.0 3.0 2 1 1 4 4 4 1 HEAT repeats DUF2674 PF10879.8 EAX83177.1 - 0.028 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) PWI PF01480.17 EAX83178.1 - 0.016 15.5 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 PWI domain OmdA PF13376.6 EAX83178.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated T5orf172 PF10544.9 EAX83179.1 - 1.7e-06 28.5 0.2 3.3e-06 27.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain AAA_11 PF13086.6 EAX83181.1 - 0.0092 15.8 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX83181.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX83181.1 - 0.033 14.5 0.1 0.049 14.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX83181.1 - 0.04 14.2 0.1 0.06 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EAX83181.1 - 0.041 13.9 0.1 0.05 13.6 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX83181.1 - 0.042 13.3 0.1 0.049 13.1 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX83181.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4108 PF13390.6 EAX83183.1 - 1.4e-64 216.3 5.4 1.6e-64 216.2 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PG_binding_2 PF08823.11 EAX83184.1 - 0.0064 16.8 0.1 0.21 11.9 0.1 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain DUF87 PF01935.17 EAX83184.1 - 0.13 12.3 0.6 0.4 10.7 0.6 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain DUF3839 PF12943.7 EAX83185.1 - 1.3e-147 489.7 11.2 1.5e-147 489.5 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX83185.1 - 0.039 14.2 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAX83185.1 - 0.13 12.9 0.9 0.65 10.7 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX83185.1 - 2.5 8.6 5.4 1.1 9.8 0.5 2.9 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX83187.1 - 0.048 14.1 1.3 0.062 13.8 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83187.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX83189.1 - 4.1e-43 145.8 0.0 7e-43 145.0 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX83189.1 - 0.0084 16.7 0.0 0.02 15.5 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX83189.1 - 0.96 9.5 4.1 2.5 8.1 0.3 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF4106 PF13388.6 EAX83190.1 - 6.9e-179 595.4 28.0 2.7e-178 593.5 28.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX83190.1 - 0.057 13.2 0.3 0.097 12.5 0.3 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX83190.1 - 1.9 8.4 17.4 2.3 8.1 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_5 PF13306.6 EAX83197.1 - 6.1e-46 155.5 56.2 1.9e-17 63.4 10.1 3.6 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX83197.1 - 2.1e-11 43.4 16.1 0.015 15.1 0.1 7.3 3 2 5 9 9 9 7 Leucine rich repeat Mid2 PF04478.12 EAX83197.1 - 0.00022 21.1 0.6 0.00055 19.8 0.6 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM51 PF15345.6 EAX83197.1 - 0.00064 19.6 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 LRR_4 PF12799.7 EAX83197.1 - 0.012 16.0 39.5 0.42 11.1 0.1 8.3 3 2 4 8 8 8 0 Leucine Rich repeats (2 copies) SKG6 PF08693.10 EAX83197.1 - 0.017 14.6 1.1 0.029 13.8 1.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3827 PF12877.7 EAX83197.1 - 0.025 13.0 0.3 0.035 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pentapeptide_3 PF13576.6 EAX83197.1 - 1.3 9.2 4.5 15 5.8 0.1 4.1 4 2 0 4 4 4 0 Pentapeptide repeats (9 copies) LRR_5 PF13306.6 EAX83198.1 - 1.1e-106 351.9 74.2 3.9e-23 81.8 5.0 7.4 1 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX83198.1 - 2.4e-24 84.8 6.8 0.04 13.7 0.0 10.4 9 3 5 14 14 14 9 Leucine rich repeat LRR_4 PF12799.7 EAX83198.1 - 7.2e-06 26.3 14.4 13 6.4 0.0 8.6 7 3 1 9 9 9 2 Leucine Rich repeats (2 copies) Ly49 PF08391.10 EAX83199.1 - 0.38 11.1 2.5 0.45 10.9 2.5 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX83199.1 - 0.6 10.0 3.2 1.2 9.1 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX83200.1 - 2.3e-57 192.9 4.2 2.6e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Amidase02_C PF12123.8 EAX83202.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83203.1 - 2.4e-73 245.7 4.7 2.8e-73 245.4 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX83203.1 - 0.074 11.5 1.0 0.11 10.9 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX83205.1 - 1.2e-155 516.0 14.6 1.5e-155 515.7 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83205.1 - 0.038 14.5 2.4 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83205.1 - 0.69 10.4 6.8 2.3 8.7 0.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83205.1 - 2 9.0 7.6 0.5 10.9 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX83208.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83208.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83208.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83208.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83208.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83208.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83208.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83208.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX83208.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83208.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83208.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX83208.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX83208.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Sulfatase PF00884.23 EAX83210.1 - 2.1e-16 60.2 0.1 5.2e-16 58.9 0.1 1.7 1 1 1 2 2 2 1 Sulfatase DUF229 PF02995.17 EAX83210.1 - 0.014 14.0 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF1761 PF08570.10 EAX83210.1 - 0.039 14.2 0.7 0.14 12.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF3839 PF12943.7 EAX83211.1 - 3.1e-117 390.3 5.5 3.5e-117 390.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX83211.1 - 0.071 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Zinc binding domain KELK PF15796.5 EAX83211.1 - 0.46 11.0 2.4 1.2 9.6 0.8 2.5 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83212.1 - 5.2e-16 58.8 3.7 8e-16 58.2 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TPR_MLP1_2 PF07926.12 EAX83213.1 - 0.057 13.5 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX83213.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX83213.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family DUF3839 PF12943.7 EAX83214.1 - 1.4e-116 388.1 5.9 1.7e-116 387.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX83216.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX83217.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83217.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Spo12 PF05032.12 EAX83219.1 - 0.095 12.6 2.2 0.095 12.6 2.2 2.4 3 0 0 3 3 3 0 Spo12 family PAXIP1_C PF15364.6 EAX83221.1 - 0.082 13.2 1.6 0.15 12.4 0.7 1.9 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein BAR PF03114.18 EAX83222.1 - 0.0088 15.7 0.5 0.011 15.4 0.5 1.1 1 0 0 1 1 1 1 BAR domain Arabino_trans_C PF14896.6 EAX83222.1 - 0.026 13.5 0.0 0.027 13.5 0.0 1.0 1 0 0 1 1 1 0 EmbC C-terminal domain ABC_tran_CTD PF16326.5 EAX83222.1 - 0.12 12.7 0.0 8 6.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF2897 PF11446.8 EAX83223.1 - 0.4 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) NMT PF01233.19 EAX83223.1 - 3.4 7.5 5.8 0.24 11.2 0.8 1.7 2 1 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4108 PF13390.6 EAX83224.1 - 1.7e-64 216.0 6.3 1.9e-64 215.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX83224.1 - 0.1 12.8 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Gly-zipper_Omp PF13488.6 EAX83225.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX83225.1 - 1.4 9.2 7.1 2.3 8.6 6.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Pox_A32 PF04665.12 EAX83227.1 - 6.7e-07 29.0 2.3 6.7e-07 29.0 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83227.1 - 3.1e-05 24.2 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83227.1 - 4.5e-05 23.3 0.3 0.35 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83227.1 - 0.00014 21.9 3.2 0.00032 20.7 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83227.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83227.1 - 0.0016 18.3 0.5 0.003 17.4 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83227.1 - 0.0023 17.6 0.4 0.017 14.8 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83227.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83227.1 - 0.073 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX83227.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83227.1 - 0.34 11.2 3.8 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX83228.1 - 3.7e-41 139.5 0.7 7.4e-41 138.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83228.1 - 0.00058 20.0 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX83229.1 - 1.3e-06 28.8 0.2 2.7e-06 27.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX83229.1 - 0.17 12.6 0.4 0.44 11.3 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF846 PF05832.12 EAX83230.1 - 0.048 13.7 0.1 0.094 12.8 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) HTH_Tnp_4 PF13613.6 EAX83232.1 - 0.004 16.9 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF4106 PF13388.6 EAX83232.1 - 1.2 8.2 7.9 1.8 7.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SUZ PF12752.7 EAX83232.1 - 4 8.3 9.0 1.2e+02 3.6 7.9 2.5 2 0 0 2 2 2 0 SUZ domain FliJ PF02050.16 EAX83233.1 - 0.028 14.6 0.1 0.035 14.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX83234.1 - 2.2e-71 239.3 3.5 2.9e-71 238.9 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX83238.1 - 1.2e-154 512.8 12.3 1.5e-154 512.4 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83238.1 - 0.71 10.4 4.3 8.7 6.9 0.1 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RRP36 PF06102.12 EAX83239.1 - 1.9e-34 119.1 15.8 2.2e-34 118.8 15.8 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 BRCA-2_OB3 PF09104.10 EAX83239.1 - 0.055 13.1 0.1 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF4407 PF14362.6 EAX83239.1 - 0.083 12.2 3.1 0.11 11.8 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nmad5 PF18757.1 EAX83239.1 - 0.25 11.5 5.3 0.51 10.5 0.9 2.2 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 Fungal_TACC PF12709.7 EAX83239.1 - 0.43 11.0 0.2 0.43 11.0 0.2 2.9 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins BET PF17035.5 EAX83240.1 - 0.0021 18.2 0.3 0.0045 17.1 0.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EAX83240.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF1574 PF07611.11 EAX83240.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) zf-C2H2_aberr PF17017.5 EAX83241.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger MULE PF10551.9 EAX83242.1 - 3.1e-09 37.1 0.1 7.3e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX83242.1 - 0.05 14.3 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3781 PF12636.7 EAX83243.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX83244.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX83245.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX83246.1 - 5.3e-137 455.0 11.8 1.4e-136 453.6 11.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83246.1 - 1.3 9.5 5.3 5.2 7.6 0.4 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83247.1 - 3.2e-06 27.6 0.1 7.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83247.1 - 0.0081 16.0 2.4 0.049 13.5 1.2 2.6 2 1 0 2 2 2 1 KilA-N domain FRG PF08867.11 EAX83247.1 - 0.11 13.5 0.1 2 9.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain DUF3839 PF12943.7 EAX83248.1 - 2e-156 518.6 13.7 2.5e-156 518.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX83248.1 - 0.068 13.4 0.4 1.4 9.2 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX83248.1 - 0.068 13.0 0.8 0.29 11.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX83248.1 - 0.12 12.8 0.5 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83248.1 - 1.3 9.5 7.6 2.1 8.9 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX83249.1 - 2.3e-41 140.1 0.6 6e-41 138.8 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX83249.1 - 0.011 15.0 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX83249.1 - 0.19 12.3 2.1 1.9 9.1 0.4 2.4 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 T5orf172 PF10544.9 EAX83250.1 - 9.9e-07 29.3 0.2 2.6e-06 27.9 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83250.1 - 0.021 14.6 0.5 0.16 11.8 0.1 2.5 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX83250.1 - 0.13 11.8 0.4 1.7 8.1 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83251.1 - 2.7e-43 146.4 0.3 7.2e-43 145.0 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83251.1 - 0.02 15.5 0.1 0.056 14.1 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX83252.1 - 4.4e-08 32.9 0.9 5.4e-08 32.6 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83252.1 - 0.0037 16.9 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Rad10 PF03834.14 EAX83252.1 - 0.028 14.5 0.5 0.066 13.2 0.4 1.6 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF3783 PF12646.7 EAX83252.1 - 0.065 13.2 0.4 0.58 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX83252.1 - 0.072 12.8 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4108 PF13390.6 EAX83253.1 - 1.5e-53 180.6 7.7 1.6e-53 180.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83255.1 - 5.9e-07 29.2 2.8 8.3e-07 28.7 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83255.1 - 0.0042 16.8 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83255.1 - 0.052 13.0 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83255.1 - 0.059 13.1 0.2 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83255.1 - 0.099 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX83255.1 - 0.11 12.9 3.5 0.49 10.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX83255.1 - 0.18 11.8 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83255.1 - 0.42 10.8 8.6 5.4 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX83256.1 - 2.7e-09 36.4 0.9 5.4e-09 35.4 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX83256.1 - 0.11 12.6 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAX83257.1 - 9e-156 516.5 14.3 1.1e-155 516.1 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83257.1 - 0.034 14.5 0.6 0.83 10.1 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX83257.1 - 0.16 12.5 0.2 0.16 12.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83257.1 - 0.25 11.8 4.9 2.1 8.9 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phage_mat-A PF03863.13 EAX83258.1 - 0.083 11.8 0.1 0.093 11.6 0.1 1.0 1 0 0 1 1 1 0 Phage maturation protein HTH_19 PF12844.7 EAX83258.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Meiosis_expr PF15163.6 EAX83259.1 - 0.024 15.3 0.9 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX83259.1 - 0.16 11.7 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX83259.1 - 8.6 6.4 13.7 0.14 12.0 2.8 3.2 4 1 0 4 4 4 0 Spo12 family DUF1947 PF09183.10 EAX83260.1 - 0.051 13.9 0.6 0.26 11.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) KilA-N PF04383.13 EAX83261.1 - 3.8e-10 39.6 0.0 8.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX83262.1 - 2.5e-153 508.5 15.4 3.1e-153 508.2 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83262.1 - 0.094 13.2 7.8 0.25 11.8 0.9 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX83262.1 - 0.12 12.8 2.5 0.3 11.5 0.6 2.2 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX83262.1 - 0.15 12.3 5.1 0.47 10.8 0.1 3.4 2 2 0 2 2 2 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX83262.1 - 0.21 11.4 2.0 0.49 10.2 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4106 PF13388.6 EAX83263.1 - 5.6e-268 888.9 51.6 7.2e-150 499.8 22.4 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX83263.1 - 0.025 14.9 2.6 0.11 12.8 0.2 3.0 3 0 0 3 3 3 0 Kidney androgen-regulated KilA-N PF04383.13 EAX83264.1 - 2.8e-12 46.5 0.7 5.3e-12 45.6 0.7 1.5 1 0 0 1 1 1 1 KilA-N domain NTS PF15447.6 EAX83264.1 - 0.38 11.3 3.4 3 8.4 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX83265.1 - 8.5e-156 516.5 12.2 1.1e-155 516.2 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX83265.1 - 0.061 13.5 0.8 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF29 DUF2408 PF10303.9 EAX83265.1 - 1.9 9.1 5.2 0.81 10.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX83266.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX83267.1 - 0.021 15.3 0.5 0.044 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX83268.1 - 1.6e-107 351.5 78.6 4.5e-34 116.3 15.0 8.6 8 3 2 10 10 10 5 Phage tail repeat like DUF4943 PF16301.5 EAX83268.1 - 0.0085 16.1 2.1 4.2 7.4 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4943) DUF4116 PF13475.6 EAX83268.1 - 0.032 14.0 0.1 0.087 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Apolipoprotein PF01442.18 EAX83268.1 - 0.087 12.7 8.1 0.59 10.0 1.5 3.4 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain Big_7 PF17957.1 EAX83268.1 - 2.2 9.1 6.6 27 5.6 0.2 3.3 3 0 0 3 3 3 0 Bacterial Ig domain EpuA PF11772.8 EAX83269.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX83270.1 - 1.8e-08 34.3 8.6 6.3e-08 32.6 2.4 4.8 5 1 1 6 6 6 2 Phage tail repeat like EpuA PF11772.8 EAX83270.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Transposase_mut PF00872.18 EAX83271.1 - 0.0016 17.4 0.1 0.0019 17.1 0.1 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX83271.1 - 0.051 13.3 0.1 0.86 9.3 0.0 1.9 1 1 1 2 2 2 0 Transposase MULE PF10551.9 EAX83271.1 - 0.11 12.9 0.3 0.35 11.3 0.1 1.9 2 0 0 2 2 2 0 MULE transposase domain DprA_WH PF17782.1 EAX83271.1 - 0.13 12.4 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 DprA winged helix domain rve PF00665.26 EAX83272.1 - 0.037 14.2 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_AraC PF00165.23 EAX83272.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family PTR PF12789.7 EAX83274.1 - 1.4e-09 37.9 0.5 1.4e-09 37.9 0.5 4.2 4 2 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX83274.1 - 0.13 12.0 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) T5orf172 PF10544.9 EAX83275.1 - 3.1e-07 30.9 0.3 8.7e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX83275.1 - 0.044 13.3 0.1 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83275.1 - 0.094 12.6 0.2 0.79 9.6 0.0 2.5 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX83276.1 - 6.1e-157 520.3 15.4 7.5e-157 520.0 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83276.1 - 0.12 12.2 1.8 0.29 11.0 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83276.1 - 1.4 9.4 6.8 2.1 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83277.1 - 3.7e-141 468.6 10.9 4.6e-141 468.3 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83277.1 - 0.05 14.1 2.9 0.075 13.5 0.4 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83277.1 - 0.31 11.5 8.3 3 8.4 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83277.1 - 0.91 10.1 4.3 0.81 10.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX83277.1 - 1.2 9.5 7.2 9.9 6.5 0.3 4.0 4 1 1 5 5 5 0 Tup N-terminal AbLIM_anchor PF16182.5 EAX83278.1 - 4.1 7.1 14.6 0.82 9.4 11.0 1.6 1 1 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Fibritin_C PF07921.12 EAX83279.1 - 2.1 8.5 7.7 19 5.4 0.1 2.9 1 1 1 2 2 2 0 Fibritin C-terminal region ANAPC4_WD40 PF12894.7 EAX83281.1 - 3.9e-09 36.7 0.1 0.032 14.5 0.0 5.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX83281.1 - 5.3e-09 36.6 1.0 0.032 15.1 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAX83281.1 - 0.063 12.2 0.0 0.37 9.7 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Itfg2 PF15907.5 EAX83281.1 - 0.11 11.5 0.0 0.45 9.5 0.0 1.9 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Peptidase_M28 PF04389.17 EAX83282.1 - 2.1e-10 40.6 0.0 4.9e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 Herpes_IE2_3 PF03361.14 EAX83283.1 - 0.0035 17.2 1.2 0.16 11.9 0.3 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX83283.1 - 0.0054 17.0 3.7 0.6 10.4 0.9 2.4 2 0 0 2 2 2 2 PPP5 TPR repeat region OSCP PF00213.18 EAX83284.1 - 0.029 14.5 0.8 0.067 13.3 0.1 1.9 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit DUF659 PF04937.15 EAX83285.1 - 0.022 14.6 0.1 0.4 10.5 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF 659) TMP PF05017.14 EAX83286.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat RLL PF10036.9 EAX83289.1 - 0.09 12.6 3.4 0.15 11.9 3.3 1.4 1 1 1 2 2 2 0 RNA transcription, translation and transport factor protein DUF2897 PF11446.8 EAX83289.1 - 0.49 10.3 2.8 0.87 9.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX83290.1 - 5.8e-07 29.2 3.0 5.8e-07 29.2 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83290.1 - 2.8e-05 24.4 0.3 0.00021 21.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83290.1 - 4.7e-05 23.2 0.2 0.41 10.3 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83290.1 - 0.00016 21.8 3.2 0.00036 20.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83290.1 - 0.00053 19.8 0.1 0.00098 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83290.1 - 0.0016 18.3 0.8 0.0032 17.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83290.1 - 0.0017 18.0 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX83290.1 - 0.0064 15.4 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase AAA_19 PF13245.6 EAX83290.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX83290.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX83290.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83290.1 - 0.089 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83290.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83290.1 - 1.8 8.8 6.5 11 6.4 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX83290.1 - 9.4 6.4 14.0 2.8 8.1 0.1 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX83291.1 - 2.7e-43 146.4 0.7 5.5e-43 145.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83291.1 - 0.021 15.0 0.1 0.052 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) LOH1CR12 PF10158.9 EAX83291.1 - 1.2 9.1 4.3 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX83292.1 - 1.1e-06 29.2 0.3 2.7e-06 27.8 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83292.1 - 0.015 14.8 0.4 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83293.1 - 8.4e-44 148.0 1.3 1.1e-43 147.6 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83293.1 - 0.031 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX83294.1 - 2.1e-06 28.2 0.2 4.8e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83294.1 - 0.0055 16.6 0.1 0.041 13.7 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX83294.1 - 0.08 12.5 0.6 0.71 9.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX83295.1 - 6.6e-80 268.1 11.7 8.7e-80 267.7 11.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX83295.1 - 0.068 12.7 0.5 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Trypan_PARP PF05887.11 EAX83296.1 - 0.035 14.1 11.0 0.036 14.1 11.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83296.1 - 5.3 7.5 9.0 6.4 7.2 9.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TALPID3 PF15324.6 EAX83296.1 - 5.9 4.4 18.5 6.6 4.3 18.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GPS2_interact PF15784.5 EAX83297.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83297.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX83298.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) BLOC1S3 PF15753.5 EAX83299.1 - 0.05 13.7 0.3 0.071 13.2 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ATG16 PF08614.11 EAX83299.1 - 0.083 13.1 2.1 0.11 12.6 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 EAX83299.1 - 0.1 12.9 0.9 0.14 12.5 0.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3839 PF12943.7 EAX83300.1 - 8.4e-156 516.5 13.1 1.1e-155 516.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83300.1 - 0.13 12.8 4.6 1.7 9.1 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83300.1 - 0.49 11.0 5.3 0.44 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 EAX83302.1 - 0.037 14.1 0.2 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX83302.1 - 0.092 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX83302.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX83303.1 - 6.1e-155 513.7 15.0 7.6e-155 513.4 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83303.1 - 0.031 14.7 1.7 0.14 12.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX83303.1 - 0.12 12.8 0.4 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83303.1 - 0.38 11.2 7.7 1.9 9.0 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase THOC7 PF05615.13 EAX83303.1 - 1.4 9.2 5.1 0.35 11.2 0.3 2.4 3 1 0 3 3 3 0 Tho complex subunit 7 Rx_N PF18052.1 EAX83303.1 - 5 7.5 5.6 5.7 7.3 0.1 3.3 2 2 2 4 4 4 0 Rx N-terminal domain Tup_N PF08581.10 EAX83303.1 - 6.4 7.2 7.4 14 6.1 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal Ferritin PF00210.24 EAX83304.1 - 4.4e-27 94.8 1.7 4.9e-27 94.6 1.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 EAX83304.1 - 3.4e-05 24.3 1.0 3.6e-05 24.2 1.0 1.1 1 0 0 1 1 1 1 Rubrerythrin COesterase PF00135.28 EAX83305.1 - 0.0016 17.4 0.1 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 EAX83305.1 - 0.0017 17.6 0.1 0.0046 16.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 EAX83305.1 - 0.0018 17.2 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Chlorophyllase2 PF12740.7 EAX83305.1 - 0.0035 16.3 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EAX83305.1 - 0.0045 16.1 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 EAX83305.1 - 0.1 13.2 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PSP1 PF04468.12 EAX83306.1 - 8.7e-33 112.5 2.1 7.1e-32 109.5 0.8 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region HAS-barrel PF09378.10 EAX83306.1 - 0.091 12.9 4.1 0.085 13.0 0.6 2.2 2 0 0 2 2 2 0 HAS barrel domain DAO_C PF16901.5 EAX83307.1 - 0.16 11.8 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF4108 PF13390.6 EAX83308.1 - 3e-62 208.8 6.6 3.3e-62 208.6 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF262 PF03235.14 EAX83310.1 - 6.5 6.9 9.9 2.5 8.2 6.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF262 DUF1947 PF09183.10 EAX83312.1 - 0.012 15.9 0.2 0.096 13.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) EpuA PF11772.8 EAX83312.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta GPS2_interact PF15784.5 EAX83313.1 - 0.091 13.2 1.6 0.12 12.8 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83313.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83314.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX83315.1 - 0.0051 16.8 0.2 0.0067 16.4 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX83316.1 - 0.012 16.0 0.7 0.015 15.7 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX83316.1 - 1.8 7.5 4.4 1.8 7.5 4.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX83316.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX83316.1 - 6.4 6.8 7.6 6.9 6.7 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 LBR_tudor PF09465.10 EAX83317.1 - 0.00054 19.7 0.3 0.001 18.9 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX83317.1 - 0.044 14.2 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor Ank_2 PF12796.7 EAX83319.1 - 1.7e-35 121.4 1.2 5.1e-14 52.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX83319.1 - 9e-25 86.0 0.0 0.00012 22.4 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX83319.1 - 2e-23 82.1 0.2 1.9e-06 28.0 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX83319.1 - 2.7e-23 82.0 0.0 7.1e-09 36.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83319.1 - 1.6e-18 64.9 0.0 0.0077 16.7 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat HOOK PF05622.12 EAX83319.1 - 6.5e-06 24.6 14.2 8.3e-06 24.2 14.2 1.1 1 0 0 1 1 1 1 HOOK protein HR1 PF02185.16 EAX83319.1 - 0.00056 20.0 18.8 0.23 11.6 2.6 3.6 1 1 2 3 3 3 3 Hr1 repeat MAD PF05557.13 EAX83319.1 - 0.00058 18.4 18.5 0.00078 17.9 18.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Spc7 PF08317.11 EAX83319.1 - 0.00077 18.4 15.3 0.0011 17.9 15.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 EAX83319.1 - 0.0016 17.4 14.6 0.0028 16.7 14.6 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DHR10 PF18595.1 EAX83319.1 - 0.0029 17.7 18.0 0.0057 16.7 18.0 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF4407 PF14362.6 EAX83319.1 - 0.0032 16.9 8.0 0.0049 16.3 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EAX83319.1 - 0.0055 16.9 17.7 0.0095 16.1 17.7 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family GAS PF13851.6 EAX83319.1 - 0.007 15.7 26.8 0.02 14.2 26.8 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 EAX83319.1 - 0.0072 16.8 16.9 0.27 11.7 4.0 2.8 1 1 1 2 2 2 2 Spectrin repeat LUC7 PF03194.15 EAX83319.1 - 0.0075 16.0 7.5 0.011 15.4 7.5 1.4 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Dam1 PF08653.10 EAX83319.1 - 0.012 15.4 6.8 1.7 8.5 0.4 3.1 1 1 2 3 3 3 0 DASH complex subunit Dam1 Golgin_A5 PF09787.9 EAX83319.1 - 0.013 15.0 15.8 0.018 14.5 15.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 EAX83319.1 - 0.016 15.7 16.8 0.062 13.8 7.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EAX83319.1 - 0.018 14.6 9.0 0.024 14.2 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.6 EAX83319.1 - 0.021 14.5 21.5 0.091 12.4 21.3 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_S46 PF10459.9 EAX83319.1 - 0.027 13.1 7.3 0.032 12.9 7.3 1.1 1 0 0 1 1 1 0 Peptidase S46 FapA PF03961.13 EAX83319.1 - 0.033 12.8 17.0 0.035 12.7 15.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A CcmH PF03918.14 EAX83319.1 - 0.035 13.4 4.0 1 8.6 1.3 2.5 1 1 1 2 2 2 0 Cytochrome C biogenesis protein TMPIT PF07851.13 EAX83319.1 - 0.042 13.1 14.9 0.064 12.5 14.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2968 PF11180.8 EAX83319.1 - 0.043 13.5 16.1 0.14 11.8 16.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4988 PF16378.5 EAX83319.1 - 0.048 13.3 11.8 0.43 10.2 6.6 2.9 1 1 1 2 2 2 0 Domain of unknown function Prefoldin PF02996.17 EAX83319.1 - 0.048 13.6 20.2 0.62 10.0 3.5 3.6 1 1 3 4 4 4 0 Prefoldin subunit V_ATPase_I PF01496.19 EAX83319.1 - 0.06 11.3 11.2 0.073 11.0 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAT PF03127.14 EAX83319.1 - 0.077 13.3 13.9 0.54 10.6 4.3 2.6 1 1 1 2 2 2 0 GAT domain Rx_N PF18052.1 EAX83319.1 - 0.077 13.3 10.0 3.3 8.0 3.0 3.4 1 1 2 3 3 3 0 Rx N-terminal domain Phage_HK97_TLTM PF06120.11 EAX83319.1 - 0.077 12.2 21.5 0.27 10.4 21.4 2.0 1 1 0 1 1 1 0 Tail length tape measure protein DUF4140 PF13600.6 EAX83319.1 - 0.081 13.4 14.0 3.1 8.3 3.2 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 EAX83319.1 - 0.12 12.8 13.2 1.4 9.4 2.4 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MIS13 PF08202.11 EAX83319.1 - 0.12 11.6 15.8 0.19 11.0 15.8 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Cep57_MT_bd PF06657.13 EAX83319.1 - 0.13 12.8 9.8 16 6.0 0.4 3.2 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 EAX83319.1 - 0.14 12.3 18.4 0.67 10.2 7.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) T2SSG PF08334.11 EAX83319.1 - 0.15 12.2 8.4 2.9 8.0 3.0 2.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein G SCO1-SenC PF02630.14 EAX83319.1 - 0.16 11.9 2.1 0.71 9.8 2.1 2.0 1 1 0 1 1 1 0 SCO1/SenC DUF16 PF01519.16 EAX83319.1 - 0.17 12.4 21.0 1.2 9.6 12.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 P66_CC PF16563.5 EAX83319.1 - 0.19 11.3 7.7 4.7 6.9 0.6 3.6 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Atg14 PF10186.9 EAX83319.1 - 0.19 10.8 13.5 0.35 9.9 13.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RILP PF11461.8 EAX83319.1 - 0.23 11.7 14.6 3.1 8.1 1.7 3.4 1 1 2 3 3 3 0 Rab interacting lysosomal protein IF-2B PF01008.17 EAX83319.1 - 0.23 10.6 3.4 0.36 10.0 3.4 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family Occludin_ELL PF07303.13 EAX83319.1 - 0.25 12.1 17.1 0.69 10.7 14.1 2.3 1 1 1 2 2 2 0 Occludin homology domain Cas_DxTHG PF09455.10 EAX83319.1 - 0.25 10.9 10.7 0.074 12.6 8.2 1.5 2 0 0 2 2 1 0 CRISPR-associated (Cas) DxTHG family LMBR1 PF04791.16 EAX83319.1 - 0.27 10.1 8.4 0.44 9.4 8.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein AAT PF03417.16 EAX83319.1 - 0.27 10.9 4.3 1.3 8.7 3.7 2.1 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DivIVA PF05103.13 EAX83319.1 - 0.29 11.2 20.4 30 4.7 20.2 3.1 1 1 0 1 1 1 0 DivIVA protein Med21 PF11221.8 EAX83319.1 - 0.39 11.0 14.3 0.4 10.9 4.9 2.7 1 1 2 3 3 3 0 Subunit 21 of Mediator complex PspA_IM30 PF04012.12 EAX83319.1 - 0.42 10.2 17.9 0.69 9.4 8.8 2.1 1 1 1 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.8 EAX83319.1 - 0.47 10.7 15.9 3.1 8.1 10.4 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MCU PF04678.13 EAX83319.1 - 0.5 10.4 5.6 1.2 9.2 5.6 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Prominin PF05478.11 EAX83319.1 - 0.52 8.2 13.2 0.64 7.9 13.2 1.1 1 0 0 1 1 1 0 Prominin HemX PF04375.14 EAX83319.1 - 0.56 9.4 15.4 0.26 10.5 13.2 1.5 2 0 0 2 2 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FliJ PF02050.16 EAX83319.1 - 0.73 10.1 19.4 0.67 10.2 12.2 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein WEMBL PF05701.11 EAX83319.1 - 0.73 8.5 18.3 1.4 7.5 17.9 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF2730 PF10805.8 EAX83319.1 - 0.74 9.9 10.0 0.73 10.0 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) SKA2 PF16740.5 EAX83319.1 - 0.75 9.6 15.2 3.5 7.4 1.6 2.4 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2203 PF09969.9 EAX83319.1 - 0.77 10.5 9.9 2.4 8.9 9.9 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sec8_exocyst PF04048.14 EAX83319.1 - 0.8 9.6 15.0 2.1 8.2 12.7 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain PilO PF04350.13 EAX83319.1 - 1.1 9.4 17.7 0.078 13.1 8.0 2.2 1 1 2 3 3 3 0 Pilus assembly protein, PilO ATP_sub_h PF10775.9 EAX83319.1 - 1.3 9.1 7.3 13 5.9 0.3 3.1 1 1 3 4 4 4 0 ATP synthase complex subunit h FliD_N PF02465.18 EAX83319.1 - 1.5 9.6 21.3 2 9.1 7.8 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HIP1_clath_bdg PF16515.5 EAX83319.1 - 1.5 9.5 18.6 4.2 8.0 8.1 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 EAX83319.1 - 1.6 8.5 24.5 2.3 8.1 7.4 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF948 PF06103.11 EAX83319.1 - 1.7 8.9 9.3 6.8 7.0 7.3 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.18 EAX83319.1 - 2.8 7.8 15.6 2.7 7.8 14.2 1.6 1 1 1 2 2 2 0 PCRF domain OmpH PF03938.14 EAX83319.1 - 2.9 8.2 27.1 14 6.1 27.1 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 EAX83319.1 - 3 8.1 21.3 6.2 7.1 20.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SLATT_5 PF18160.1 EAX83319.1 - 3.1 7.1 11.0 5.9 6.2 11.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cauli_AT PF03233.13 EAX83319.1 - 3.5 7.5 24.3 1.6 8.6 8.7 3.2 1 1 2 3 3 3 0 Aphid transmission protein DUF349 PF03993.12 EAX83319.1 - 3.6 8.0 21.1 10 6.5 8.6 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF349) CorA PF01544.18 EAX83319.1 - 4.8 6.4 11.5 37 3.5 3.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CENP-H PF05837.12 EAX83319.1 - 4.8 7.6 16.8 8.4 6.8 16.3 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 EAX83319.1 - 4.9 7.2 11.2 64 3.6 11.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 EAX83319.1 - 5.2 7.2 20.4 1.3e+04 -3.6 20.4 2.7 1 1 0 1 1 0 0 Swi5 GrpE PF01025.19 EAX83319.1 - 5.4 6.6 23.4 19 4.9 10.8 2.3 1 1 1 2 2 2 0 GrpE FlxA PF14282.6 EAX83319.1 - 5.9 6.9 27.0 14 5.7 18.0 2.5 1 1 2 3 3 3 0 FlxA-like protein DUF3450 PF11932.8 EAX83319.1 - 6 6.1 19.1 13 5.0 19.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EAX83319.1 - 7.4 7.1 22.8 18 5.9 22.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Laminin_II PF06009.12 EAX83319.1 - 7.8 6.5 16.5 16 5.5 16.5 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF4108 PF13390.6 EAX83320.1 - 5.8e-64 214.3 6.4 6.4e-64 214.2 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83322.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83322.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83322.1 - 5.3e-05 23.0 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83322.1 - 0.00018 21.6 3.8 0.00044 20.3 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83322.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83322.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83322.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83322.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83322.1 - 0.071 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX83322.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83322.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX83322.1 - 0.22 11.8 4.8 3.3 8.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83323.1 - 3e-150 498.4 17.3 3.8e-150 498.1 17.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX83323.1 - 0.11 12.0 0.1 0.36 10.3 0.1 1.9 1 1 0 1 1 1 0 SLOG cluster2 KELK PF15796.5 EAX83323.1 - 0.77 10.3 7.7 2.2 8.8 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX83324.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83324.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX83325.1 - 0.08 11.9 0.1 0.083 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Prion PF00377.18 EAX83328.1 - 0.11 12.3 0.2 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Trypan_PARP PF05887.11 EAX83329.1 - 0.041 13.9 8.7 0.064 13.2 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX83330.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83330.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Tnp_22_trimer PF17489.2 EAX83332.1 - 0.32 11.0 5.2 8.7 6.4 0.2 2.4 1 1 1 2 2 2 0 L1 transposable element trimerization domain DUF3839 PF12943.7 EAX83333.1 - 1.6e-156 518.9 13.8 2e-156 518.6 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83333.1 - 0.061 13.8 1.5 0.3 11.5 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83333.1 - 0.43 11.1 6.0 2 8.9 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX83336.1 - 1.3e-62 209.9 5.9 1.5e-62 209.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RFX_DNA_binding PF02257.15 EAX83337.1 - 0.00016 22.2 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX83337.1 - 0.00064 20.2 1.7 0.00098 19.6 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX83337.1 - 0.034 14.1 0.8 0.073 13.1 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PSP PF04046.16 EAX83338.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83339.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX83339.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_D5 PF03288.16 EAX83341.1 - 3.5e-05 24.2 4.0 0.00027 21.4 4.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX83341.1 - 0.044 14.4 0.1 0.08 13.6 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX83341.1 - 0.051 13.6 0.2 0.077 13.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX83343.1 - 1.9e-34 117.8 0.3 4.9e-34 116.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83343.1 - 0.057 14.0 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Trypan_PARP PF05887.11 EAX83344.1 - 0.098 12.6 11.5 0.16 12.0 11.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83344.1 - 9.4 6.7 7.4 14 6.1 7.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX83345.1 - 0.045 12.7 0.3 0.045 12.7 0.3 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3285 PF11688.8 EAX83347.1 - 0.089 12.7 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) GPS2_interact PF15784.5 EAX83348.1 - 0.026 14.9 1.5 0.035 14.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83348.1 - 0.099 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX83350.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83350.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83350.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83350.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83350.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83350.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83350.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83350.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83350.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83350.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83350.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83350.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83351.1 - 5e-149 494.4 14.0 6.1e-149 494.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83351.1 - 0.13 12.7 0.2 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83351.1 - 0.19 12.2 6.2 4.6 7.8 0.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX83352.1 - 1.7e-56 190.1 7.2 1.9e-56 190.0 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX83353.1 - 0.009 16.3 5.8 0.011 16.1 5.8 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Btz PF09405.10 EAX83353.1 - 1 9.6 10.8 1.9 8.8 10.8 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF3464 PF11947.8 EAX83353.1 - 3.7 7.3 9.1 6.3 6.5 9.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA_22 PF13401.6 EAX83354.1 - 7.3e-05 23.1 0.0 0.00038 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83354.1 - 0.00026 21.1 2.8 0.00051 20.1 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83354.1 - 0.00068 19.4 0.0 0.00091 19.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83354.1 - 0.0014 18.5 1.0 0.0049 16.7 1.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83354.1 - 0.0037 17.0 0.2 0.26 11.0 0.0 2.6 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX83354.1 - 0.018 15.4 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX83354.1 - 0.028 14.2 0.2 0.038 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX83354.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83354.1 - 0.087 13.2 0.0 0.51 10.8 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NIBRIN_BRCT_II PF16508.5 EAX83354.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein AAA_25 PF13481.6 EAX83354.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX83354.1 - 0.25 11.6 4.7 5.4 7.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4106 PF13388.6 EAX83355.1 - 7.1e-273 905.0 39.0 2e-270 897.0 39.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX83355.1 - 0.036 14.4 0.1 0.69 10.2 0.2 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX83355.1 - 0.12 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIIA PF03153.13 EAX83355.1 - 0.36 10.8 29.7 0.053 13.5 23.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DegS PF05384.11 EAX83355.1 - 0.55 9.7 8.1 0.13 11.7 1.2 2.2 2 0 0 2 2 2 0 Sensor protein DegS Pkinase PF00069.25 EAX83357.1 - 7.9e-25 87.7 0.0 9.3e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX83357.1 - 1.3e-09 37.8 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX83357.1 - 4.6e-05 23.5 0.0 0.064 13.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAX83357.1 - 0.0043 16.4 0.7 0.0088 15.4 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cullin_Nedd8 PF10557.9 EAX83357.1 - 0.057 13.5 0.6 0.59 10.2 0.2 2.5 2 0 0 2 2 2 0 Cullin protein neddylation domain Kinase-like PF14531.6 EAX83357.1 - 0.07 12.4 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pox_A32 PF04665.12 EAX83358.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX83358.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase ResIII PF04851.15 EAX83359.1 - 4.7e-05 23.4 2.6 8.8e-05 22.6 2.6 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83359.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX83359.1 - 0.00037 20.8 0.0 0.00062 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX83359.1 - 0.00055 19.8 0.7 0.0016 18.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83359.1 - 0.0066 16.8 0.0 0.0088 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83359.1 - 0.029 14.1 0.2 0.18 11.5 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX83359.1 - 0.04 13.4 0.1 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83359.1 - 0.1 12.8 4.9 1.9 8.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_25 PF13481.6 EAX83359.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX83359.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3464 PF11947.8 EAX83360.1 - 0.88 9.3 2.6 1.5 8.6 2.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4108 PF13390.6 EAX83361.1 - 6.7e-63 210.9 8.7 7.4e-63 210.7 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX83363.1 - 1.8e-55 184.9 29.3 3.3e-33 113.5 13.6 5.0 5 2 1 6 6 6 2 Phage tail repeat like RACo_linker PF17650.1 EAX83363.1 - 0.061 13.2 0.2 2.4 8.1 0.1 2.9 2 1 1 3 3 3 0 RACo linker region DUF4116 PF13475.6 EAX83363.1 - 0.1 12.4 0.1 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) B9-C2 PF07162.11 EAX83364.1 - 1.7e-40 139.0 0.0 1.9e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ribosomal_L36e PF01158.18 EAX83365.1 - 9e-21 73.9 2.7 1.1e-20 73.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EAX83365.1 - 0.051 13.4 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF3839 PF12943.7 EAX83366.1 - 3.2e-80 269.1 10.3 4.3e-80 268.6 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83366.1 - 0.29 11.0 2.0 1 9.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4106 PF13388.6 EAX83367.1 - 6e-179 595.6 18.0 7.1e-179 595.4 18.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX83367.1 - 0.00054 20.2 0.1 0.034 14.4 0.3 2.2 2 0 0 2 2 2 1 Kidney androgen-regulated DegS PF05384.11 EAX83367.1 - 0.044 13.3 2.0 0.066 12.7 2.0 1.2 1 0 0 1 1 1 0 Sensor protein DegS Peptidase_S28 PF05577.12 EAX83367.1 - 0.34 9.7 5.1 0.45 9.2 5.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 eIF3_N PF09440.10 EAX83367.1 - 0.56 10.6 4.2 0.66 10.4 1.4 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain BA14K PF07886.11 EAX83367.1 - 9 6.3 5.6 28 4.7 0.2 3.3 2 1 0 3 3 3 0 BA14K-like protein Ank_4 PF13637.6 EAX83368.1 - 4.3e-10 39.9 0.1 4.8e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83368.1 - 1.3e-06 28.2 0.2 0.0039 17.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX83368.1 - 5.2e-06 26.7 0.1 0.11 13.0 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX83368.1 - 0.00033 21.2 0.1 0.00036 21.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX83368.1 - 0.00044 20.5 0.3 0.00073 19.8 0.3 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX83368.1 - 0.028 14.2 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein Ank PF00023.30 EAX83369.1 - 9.1e-40 133.4 7.1 4.2e-08 33.3 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX83369.1 - 7.9e-38 128.4 17.9 8.8e-09 35.7 0.2 6.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX83369.1 - 3.1e-35 120.6 14.7 3.9e-13 49.8 2.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX83369.1 - 1.4e-30 101.9 9.8 0.00052 20.3 0.3 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX83369.1 - 1.3e-20 73.2 5.4 8e-09 35.6 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX83369.1 - 4.7e-09 36.1 15.5 1.9e-06 27.7 0.6 4.5 2 1 0 3 3 3 2 Domain of unknown function (DUF3447) PTCB-BRCT PF12738.7 EAX83369.1 - 0.00044 20.1 0.4 1.5 8.9 0.0 4.8 3 1 3 6 6 6 1 twin BRCT domain Mic1 PF07035.12 EAX83369.1 - 0.0091 15.7 0.6 7.1 6.3 0.0 3.4 1 1 3 4 4 4 2 Colon cancer-associated protein Mic1-like ResIII PF04851.15 EAX83370.1 - 5.5e-05 23.2 1.9 8.6e-05 22.6 1.4 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83370.1 - 0.00049 19.9 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX83370.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX83370.1 - 0.0017 18.2 0.2 0.0031 17.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EAX83370.1 - 0.0099 16.2 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPK_catalytic PF04263.16 EAX83370.1 - 0.026 14.6 0.7 0.37 10.8 0.7 2.1 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX83370.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX83370.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX83370.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF573 PF04504.14 EAX83370.1 - 0.3 11.8 8.0 0.14 12.9 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF573 KilA-N PF04383.13 EAX83372.1 - 8.5e-43 144.8 0.7 1.6e-42 143.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83372.1 - 0.0068 17.0 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX83373.1 - 1.1e-06 28.3 2.2 1.1e-06 28.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83373.1 - 2.9e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83373.1 - 4.6e-05 23.2 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83373.1 - 0.00018 21.6 3.4 0.00041 20.4 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83373.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83373.1 - 0.0015 18.4 0.5 0.0035 17.2 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83373.1 - 0.0019 17.9 0.4 0.012 15.3 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83373.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX83373.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX83373.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX83373.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83373.1 - 0.092 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX83373.1 - 0.19 12.1 3.0 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX83373.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX83375.1 - 5.9e-63 211.1 5.8 6.6e-63 210.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Cnd1 PF12717.7 EAX83376.1 - 0.002 18.2 2.2 0.0027 17.8 2.2 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF4184 PF13803.6 EAX83378.1 - 0.087 12.5 1.6 0.13 12.0 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) ABC2_membrane_3 PF12698.7 EAX83378.1 - 1.7 7.6 6.0 2.3 7.2 6.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Yip1 PF04893.17 EAX83378.1 - 8.8 6.0 16.1 2 8.1 12.4 1.7 2 0 0 2 2 2 0 Yip1 domain DDE_1 PF03184.19 EAX83379.1 - 3.1e-14 53.0 0.0 3.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Collagen_bind_2 PF12904.7 EAX83380.1 - 0.12 12.4 0.0 4.7 7.3 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase LRRCT PF01463.24 EAX83381.1 - 2.3e-05 24.6 1.4 1.1e+02 3.7 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat C-terminal domain CdiI_2 PF18593.1 EAX83381.1 - 0.00027 21.5 0.0 1.4e+02 3.2 0.0 5.0 5 0 0 5 5 5 0 CdiI immunity protein Zincin_1 PF06262.11 EAX83381.1 - 0.0038 17.3 0.5 2.3e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 Zincin-like metallopeptidase Trypan_PARP PF05887.11 EAX83382.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83382.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CHASE3 PF05227.13 EAX83385.1 - 0.019 14.9 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 CHASE3 domain DUF3685 PF12452.8 EAX83385.1 - 0.056 13.2 0.1 0.077 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) Amidase02_C PF12123.8 EAX83387.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83388.1 - 4.8e-72 241.4 4.5 5.7e-72 241.2 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX83388.1 - 0.16 10.4 1.0 0.21 10.0 1.0 1.1 1 0 0 1 1 1 0 Lipoxygenase TMP PF05017.14 EAX83390.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF4108 PF13390.6 EAX83391.1 - 8.5e-58 194.3 5.6 9.5e-58 194.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX83391.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX83392.1 - 7.4 6.5 6.4 15 5.5 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) TPR_MLP1_2 PF07926.12 EAX83393.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX83393.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX83393.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX83394.1 - 4.8e-08 33.5 0.4 1e-07 32.4 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX83394.1 - 0.1 13.3 0.5 0.29 11.8 0.5 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 GPS2_interact PF15784.5 EAX83395.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83395.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83396.1 - 0.22 11.5 8.4 0.33 10.9 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83396.1 - 4.5 7.7 6.0 6.5 7.2 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX83397.1 - 0.087 12.8 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAX83398.1 - 0.37 11.3 3.7 0.48 10.9 3.7 1.3 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4107 PF13389.6 EAX83399.1 - 1.4e-65 220.4 13.4 1.6e-63 213.7 13.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83399.1 - 0.091 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TMP PF05017.14 EAX83401.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83402.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX83403.1 - 3.3e-64 213.4 0.7 3.9e-18 65.8 0.0 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83403.1 - 1.3e-30 105.3 0.1 8.8e-08 32.6 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX83403.1 - 1.6e-27 94.7 0.0 4.7e-05 23.6 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX83403.1 - 1.1e-26 92.5 0.0 1.7e-06 28.2 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83403.1 - 4.8e-21 72.6 0.0 0.023 15.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat DAP_B PF07930.12 EAX83403.1 - 0.14 12.1 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B DUF1664 PF07889.12 EAX83403.1 - 0.18 11.8 3.2 0.36 10.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EAX83403.1 - 0.22 12.2 3.5 0.52 11.0 3.5 1.6 1 0 0 1 1 1 0 SlyX DUF2115 PF09888.9 EAX83403.1 - 7.9 7.0 8.6 14 6.2 4.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) MULE PF10551.9 EAX83404.1 - 4.1e-05 23.9 0.1 7.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF4108 PF13390.6 EAX83405.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83407.1 - 3.1e-07 30.1 2.3 3.1e-07 30.1 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83407.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83407.1 - 0.00017 21.6 3.1 0.00039 20.5 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX83407.1 - 0.00023 20.9 0.3 0.36 10.5 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX83407.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83407.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83407.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83407.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83407.1 - 0.067 12.8 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX83407.1 - 0.082 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83407.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3839 PF12943.7 EAX83408.1 - 1.6e-25 90.0 4.1 2.4e-25 89.4 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX83410.1 - 1.9e-72 242.8 4.2 2.5e-72 242.3 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX83411.1 - 0.035 14.1 10.9 0.05 13.6 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX83412.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX83412.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX83413.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3781 PF12636.7 EAX83414.1 - 0.021 14.7 0.8 0.035 14.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) PTR PF12789.7 EAX83417.1 - 5.2e-12 45.6 41.5 2.3e-08 34.0 4.7 6.8 7 1 0 7 7 7 4 Phage tail repeat like Collagen PF01391.18 EAX83417.1 - 3e-05 23.7 10.3 5.2e-05 22.9 10.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX83417.1 - 0.002 18.2 5.4 0.047 13.8 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus LIFR_D2 PF17971.1 EAX83417.1 - 0.011 15.9 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain RecG_N PF17190.4 EAX83417.1 - 0.13 13.0 2.6 73 4.2 0.0 4.4 4 0 0 4 4 4 0 RecG N-terminal helical domain DUF948 PF06103.11 EAX83417.1 - 3 8.2 4.7 1.3 9.3 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EAX83417.1 - 4.5 7.3 7.9 42 4.2 0.0 4.3 3 1 1 4 4 4 0 Laminin Domain II DUF3839 PF12943.7 EAX83418.1 - 1.2e-158 525.9 12.1 1.5e-158 525.6 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83418.1 - 0.94 10.0 5.6 2 8.9 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX83419.1 - 1.6e-10 40.8 0.0 4.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain DUF4543 PF15076.6 EAX83419.1 - 0.015 15.4 0.1 0.031 14.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) ComA PF02679.15 EAX83419.1 - 0.039 13.4 0.5 0.046 13.2 0.5 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) EssA PF10661.9 EAX83419.1 - 3.4 7.5 8.5 8.4 6.2 8.4 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PSP PF04046.16 EAX83420.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83421.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX83422.1 - 0.02 15.4 0.5 0.042 14.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX83423.1 - 1.8e-32 111.1 15.2 1.8e-32 111.1 15.2 3.3 2 1 1 3 3 2 1 Phage tail repeat like DUF4116 PF13475.6 EAX83423.1 - 0.026 14.3 0.3 0.073 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX83424.1 - 7.5e-25 87.8 4.5 1.2e-24 87.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX83424.1 - 0.06 13.7 1.2 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX83424.1 - 0.18 12.3 1.5 0.66 10.5 0.3 2.0 1 1 0 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX83425.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83425.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83425.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83425.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83425.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83425.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83425.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83425.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83425.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83425.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83425.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83425.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83426.1 - 4.1e-156 517.6 12.4 5.3e-156 517.2 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83426.1 - 3.3 8.2 7.6 3.8 8.0 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ARA70 PF12489.8 EAX83427.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX83428.1 - 1.3e-07 31.3 2.9 2e-07 30.8 2.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83428.1 - 0.0022 17.7 0.2 0.0028 17.3 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83428.1 - 0.058 12.9 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83428.1 - 0.059 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83428.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83428.1 - 0.14 12.2 2.2 0.96 9.5 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) AAA_22 PF13401.6 EAX83431.1 - 0.00015 22.0 0.1 0.0008 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83431.1 - 0.0004 20.4 4.5 0.00054 20.0 3.5 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX83431.1 - 0.00077 19.2 0.4 0.23 11.2 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein DEAD PF00270.29 EAX83431.1 - 0.00079 19.2 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83431.1 - 0.0027 17.5 1.5 0.007 16.2 0.8 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83431.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX83431.1 - 0.059 13.4 0.7 0.9 9.6 0.7 2.3 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX83431.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX83431.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX83431.1 - 0.73 10.1 5.2 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX83431.1 - 3.7 8.3 10.8 0.26 12.0 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Ank_2 PF12796.7 EAX83432.1 - 1.1e-06 29.1 0.0 0.0074 16.9 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX83432.1 - 2.6e-05 24.3 0.1 2.2 9.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX83432.1 - 0.0067 17.0 0.7 5.3 7.7 0.0 3.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX83432.1 - 1 9.4 10.5 0.51 10.3 5.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) MULE PF10551.9 EAX83434.1 - 1.5e-10 41.3 1.5 2.7e-10 40.5 1.5 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX83434.1 - 0.0011 19.0 1.1 0.0042 17.2 1.1 2.0 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX83434.1 - 0.042 12.7 0.2 0.067 12.0 0.2 1.2 1 0 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX83435.1 - 5.3e-156 517.2 12.2 6.7e-156 516.9 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83435.1 - 0.15 11.9 0.7 0.49 10.2 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83435.1 - 2.8 8.5 5.7 5.3 7.6 0.3 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Apolipoprotein PF01442.18 EAX83436.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3781 PF12636.7 EAX83439.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX83440.1 - 1.1e-29 103.7 4.7 6e-28 98.0 4.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX83442.1 - 1.2e-42 144.3 0.1 1.7e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX83443.1 - 2.5e-153 508.4 12.0 3.2e-153 508.1 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX83443.1 - 0.016 15.5 0.8 5.4 7.4 0.0 3.5 3 0 0 3 3 3 0 Tup N-terminal DUF2408 PF10303.9 EAX83443.1 - 0.29 11.7 5.0 0.15 12.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83443.1 - 0.29 11.6 5.0 1.1 9.7 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX83445.1 - 0.016 15.2 9.1 0.016 15.2 9.1 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX83445.1 - 0.34 11.2 4.9 0.54 10.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX83445.1 - 2.1 8.5 6.8 3.6 7.7 6.5 1.6 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAX83446.1 - 3.1e-121 403.4 11.6 3.9e-121 403.0 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83446.1 - 0.012 16.0 1.0 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX83446.1 - 0.14 12.0 1.3 0.52 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PTR PF12789.7 EAX83447.1 - 5.6e-101 330.6 89.7 5e-33 113.0 19.7 4.8 2 2 4 6 6 5 4 Phage tail repeat like Apolipoprotein PF01442.18 EAX83447.1 - 0.00018 21.4 5.5 0.00026 20.9 5.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Peptidase_C78 PF07910.13 EAX83447.1 - 0.022 14.2 2.6 1.8 8.0 0.4 2.9 1 1 2 3 3 3 0 Peptidase family C78 DUF4116 PF13475.6 EAX83447.1 - 0.032 14.0 1.0 0.056 13.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX83447.1 - 0.19 12.1 9.5 19 5.7 0.1 4.7 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain AviRa PF11599.8 EAX83447.1 - 0.22 10.9 7.0 0.21 11.0 1.2 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa GUN4_N PF16416.5 EAX83447.1 - 0.45 10.5 4.4 12 6.0 0.2 3.6 1 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal DUF1493 PF07377.12 EAX83448.1 - 0.019 15.5 0.7 0.035 14.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX83448.1 - 0.35 10.9 5.0 4.8 7.3 0.4 2.8 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pox_A32 PF04665.12 EAX83450.1 - 6e-07 29.2 2.6 6e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83450.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83450.1 - 7e-05 22.6 0.3 0.49 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83450.1 - 0.00011 22.2 2.8 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83450.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83450.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83450.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83450.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX83450.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX83450.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83450.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83450.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83450.1 - 0.3 11.3 4.1 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX83452.1 - 0.00012 22.5 2.6 0.00076 19.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Guanylate_cyc PF00211.20 EAX83453.1 - 2.8e-43 147.7 0.1 4.4e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX83453.1 - 3.1e-08 33.8 0.9 6.4e-08 32.8 0.5 1.8 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EAX83453.1 - 0.00015 21.7 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX83453.1 - 0.00016 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX83453.1 - 0.00021 21.5 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EAX83453.1 - 0.066 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold PTR PF12789.7 EAX83455.1 - 1.1e-73 243.2 46.4 1.2e-31 108.5 13.4 4.7 2 2 2 4 4 4 3 Phage tail repeat like Peptidase_S66 PF02016.15 EAX83455.1 - 0.013 15.6 1.7 56 3.9 0.0 4.5 1 1 3 4 4 4 0 LD-carboxypeptidase N-terminal domain DUF4116 PF13475.6 EAX83455.1 - 0.04 13.7 0.9 0.074 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX83455.1 - 0.1 12.0 4.3 0.45 9.9 0.6 2.3 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Scm3 PF10384.9 EAX83456.1 - 0.071 12.9 0.8 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Centromere protein Scm3 60KD_IMP PF02096.20 EAX83456.1 - 0.52 10.2 4.1 0.63 9.9 2.2 1.9 1 1 1 2 2 2 0 60Kd inner membrane protein PTR PF12789.7 EAX83457.1 - 2.8e-25 88.1 39.7 1.4e-09 37.9 3.6 5.1 5 0 0 5 5 5 3 Phage tail repeat like EpuA PF11772.8 EAX83457.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX83457.1 - 0.13 12.2 11.1 2.8 7.8 1.8 3.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD PH_TFIIH PF08567.11 EAX83457.1 - 0.54 10.6 4.0 89 3.5 0.1 3.5 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain PA28_alpha PF02251.18 EAX83457.1 - 0.73 9.9 6.9 11 6.2 0.3 3.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit RraB PF06877.11 EAX83457.1 - 2 9.2 7.4 32 5.3 1.3 3.6 2 1 1 3 3 3 0 Regulator of ribonuclease activity B DUF2939 PF11159.8 EAX83458.1 - 0.017 15.5 0.4 0.025 15.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83458.1 - 2.7 8.0 5.7 2.9 7.9 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX83459.1 - 0.0046 16.9 0.4 0.0061 16.6 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Peptidase_S8 PF00082.22 EAX83460.1 - 6.2e-32 111.0 0.0 8.9e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family ECR1_N PF14382.6 EAX83460.1 - 0.01 15.6 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DUF4107 PF13389.6 EAX83462.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX83463.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX83466.1 - 3.3e-156 517.9 13.1 4.2e-156 517.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83466.1 - 0.2 12.2 3.2 0.69 10.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83466.1 - 0.39 11.2 4.9 5.3 7.6 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83468.1 - 5.7e-74 248.6 9.1 7.3e-74 248.3 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX83469.1 - 8.5e-59 198.9 3.0 9.5e-59 198.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX83469.1 - 0.067 13.5 0.6 0.12 12.6 0.6 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit KilA-N PF04383.13 EAX83470.1 - 1.1e-10 41.4 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain DUF4543 PF15076.6 EAX83470.1 - 0.039 14.1 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) YvrJ PF12841.7 EAX83471.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family HC2 PF07382.11 EAX83472.1 - 1.3e-09 38.4 20.8 8.1e-09 35.8 20.8 1.8 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pentapeptide_4 PF13599.6 EAX83472.1 - 1e-06 28.8 1.8 5.9e-06 26.4 1.8 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EAX83472.1 - 0.035 13.8 0.2 14 5.4 0.0 2.4 1 1 0 2 2 2 0 Pentapeptide repeats (8 copies) Keratin_B2 PF01500.17 EAX83472.1 - 0.076 13.0 0.1 0.086 12.8 0.1 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Aurora-A_bind PF09041.10 EAX83472.1 - 1.6 8.9 13.9 9.6e+03 -3.3 13.9 3.9 1 1 0 1 1 1 0 Aurora-A binding DUF2767 PF10965.8 EAX83472.1 - 5.5 7.1 10.2 2.7e+03 -1.5 10.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2767) FliD_N PF02465.18 EAX83473.1 - 0.29 11.8 4.8 0.48 11.1 4.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus O-antigen_lig PF13425.6 EAX83473.1 - 1.9 7.2 3.9 2.4 6.8 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Y_Y_Y PF07495.13 EAX83477.1 - 0.0071 16.3 2.1 4 7.5 0.1 3.9 3 0 0 3 3 3 2 Y_Y_Y domain PKD PF00801.20 EAX83477.1 - 0.011 15.6 0.8 0.26 11.2 0.1 3.7 4 0 0 4 4 4 0 PKD domain Herpes_gE PF02480.16 EAX83477.1 - 0.019 13.7 0.4 0.061 12.1 0.1 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.16 EAX83477.1 - 0.02 14.9 0.5 22 5.2 0.0 3.9 3 0 0 3 3 3 0 Immunoglobulin I-set domain Ig_3 PF13927.6 EAX83477.1 - 0.11 13.2 4.8 2 9.1 0.0 4.5 5 0 0 5 5 5 0 Immunoglobulin domain CBM_35 PF16990.5 EAX83477.1 - 0.74 10.1 5.5 9.7 6.5 0.7 3.8 4 0 0 4 4 4 0 Carbohydrate binding module (family 35) Spc7_C2 PF15577.6 EAX83477.1 - 1.2 9.2 4.5 1.8 8.7 0.1 3.3 3 0 0 3 3 3 0 Spc7_C2 Pox_D5 PF03288.16 EAX83478.1 - 0.0001 22.7 3.4 0.00062 20.2 3.4 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX83479.1 - 2e-61 206.1 8.7 2.3e-61 205.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX83480.1 - 0.57 9.9 2.0 0.91 9.3 2.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA_22 PF13401.6 EAX83481.1 - 5.4e-05 23.5 0.1 0.00031 21.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83481.1 - 6.2e-05 23.1 2.7 0.00012 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83481.1 - 0.00037 20.3 0.0 0.00052 19.8 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83481.1 - 0.00074 19.4 0.9 0.0021 17.9 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83481.1 - 0.007 16.7 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83481.1 - 0.0097 15.7 0.3 0.24 11.1 0.0 2.4 1 1 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX83481.1 - 0.047 13.1 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX83481.1 - 0.07 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX83481.1 - 0.1 13.0 0.1 0.36 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX83481.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX83481.1 - 0.19 12.0 4.3 5.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX83481.1 - 0.72 10.3 4.0 0.35 11.3 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Gly_rich PF12810.7 EAX83482.1 - 2.1e-42 145.7 37.3 2.5e-42 145.5 37.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Flavodoxin_2 PF02525.17 EAX83483.1 - 4.7e-34 117.8 0.1 5.6e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX83483.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Myb_DNA-binding PF00249.31 EAX83484.1 - 2.7e-28 97.9 3.1 2.1e-15 56.6 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX83484.1 - 2.3e-23 82.2 2.9 2e-16 60.0 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX83484.1 - 4.3e-07 29.7 0.5 0.0004 20.2 0.2 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX83484.1 - 5.6e-06 26.3 0.0 0.11 12.5 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX83484.1 - 0.013 15.7 0.2 0.024 14.8 0.2 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX83484.1 - 4.3 7.8 7.0 23 5.4 0.2 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain NESP55 PF06390.12 EAX83485.1 - 0.92 9.1 10.5 0.99 9.0 10.5 1.0 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3781 PF12636.7 EAX83486.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX83487.1 - 1.8e-72 242.8 3.3 2.3e-72 242.4 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX83489.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83489.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX83490.1 - 2.1e-151 502.1 12.1 2.6e-151 501.8 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX83490.1 - 0.52 10.7 2.5 1.4 9.3 1.1 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX83490.1 - 0.65 10.6 4.2 0.82 10.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX83491.1 - 2.3e-07 30.6 2.6 3.2e-07 30.1 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83491.1 - 0.0057 16.3 0.2 0.0072 16.0 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83491.1 - 0.04 13.4 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX83491.1 - 0.057 13.2 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX83491.1 - 0.061 13.1 0.2 0.42 10.3 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83491.1 - 0.14 12.2 2.1 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX83491.1 - 0.17 12.3 2.3 0.23 11.9 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Trypan_PARP PF05887.11 EAX83492.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83492.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX83493.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83493.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX83494.1 - 6e-155 513.8 12.4 7.3e-155 513.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83494.1 - 0.027 14.9 1.5 0.11 12.9 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83494.1 - 0.11 12.9 5.6 0.71 10.4 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phage_XkdX PF09693.10 EAX83496.1 - 0.061 13.3 1.1 1 9.5 0.5 2.4 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Amidase02_C PF12123.8 EAX83498.1 - 0.01 15.5 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase TMP PF05017.14 EAX83499.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83500.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-bind_6 PF13921.6 EAX83501.1 - 1.5e-19 69.9 1.2 3.5e-10 40.0 0.1 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX83501.1 - 1.1e-16 60.8 1.2 1.8e-07 31.2 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Snapin_Pallidin PF14712.6 EAX83501.1 - 0.055 13.9 0.4 0.055 13.9 0.4 4.0 2 1 0 3 3 3 0 Snapin/Pallidin AAR2 PF05282.11 EAX83502.1 - 0.15 11.4 0.1 11 5.4 0.0 2.1 1 1 1 2 2 2 0 AAR2 protein PTR PF12789.7 EAX83504.1 - 7.1e-21 74.0 20.1 5.3e-16 58.4 2.4 4.6 6 0 0 6 6 6 2 Phage tail repeat like DUF3839 PF12943.7 EAX83506.1 - 1.7e-156 518.8 13.4 2.2e-156 518.5 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX83506.1 - 0.02 14.9 1.4 6.2 6.8 0.0 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KELK PF15796.5 EAX83506.1 - 0.032 14.7 3.4 2.2 8.8 0.1 3.4 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX83506.1 - 0.042 14.3 2.1 0.094 13.2 0.5 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX83506.1 - 0.091 13.1 1.4 13 6.2 0.1 3.7 3 1 1 4 4 4 0 Tup N-terminal Terminase_2 PF03592.16 EAX83506.1 - 4.2 7.8 7.6 3.7 8.0 2.9 2.6 1 1 1 2 2 2 0 Terminase small subunit DUF2408 PF10303.9 EAX83506.1 - 4.6 7.8 6.1 1.1 9.9 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX83507.1 - 2.9e-06 27.8 0.2 8.8e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83507.1 - 0.0044 16.9 0.1 0.02 14.7 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX83507.1 - 0.052 13.1 1.3 0.39 10.2 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain Gly_rich PF12810.7 EAX83508.1 - 1.2e-13 51.5 22.1 2e-13 50.9 22.1 1.2 1 0 0 1 1 1 1 Glycine rich protein Pox_A32 PF04665.12 EAX83510.1 - 5.3e-07 29.4 0.3 2.2e-06 27.3 0.0 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX83510.1 - 0.12 12.0 0.1 2.5 7.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) GPS2_interact PF15784.5 EAX83512.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX83513.1 - 0.053 13.5 10.7 0.082 12.9 10.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX83514.1 - 0.002 18.5 0.3 0.0026 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX83514.1 - 0.089 12.8 0.1 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX83514.1 - 1.5 8.8 4.9 1.7 8.7 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX83516.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PSP PF04046.16 EAX83517.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83518.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat FAS_N PF17828.1 EAX83519.1 - 0.0044 17.0 0.2 0.0056 16.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX83520.1 - 0.021 14.8 7.8 0.033 14.2 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX83521.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83521.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX83523.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83523.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX83524.1 - 5.6e-26 91.5 5.0 8.5e-26 90.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX83524.1 - 0.035 14.2 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers T5orf172 PF10544.9 EAX83525.1 - 4.6e-06 27.1 0.2 1.1e-05 25.9 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83525.1 - 0.0084 15.9 0.3 0.051 13.4 0.1 2.2 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX83526.1 - 1.4e-32 111.9 1.7 1.8e-32 111.5 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX83527.1 - 6.5e-08 32.3 1.1 7.8e-08 32.1 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83527.1 - 0.0044 16.7 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX83527.1 - 0.05 13.3 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83527.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) PTR PF12789.7 EAX83528.1 - 2.5e-52 174.8 35.0 8.1e-34 115.5 16.6 4.6 2 2 2 5 5 5 2 Phage tail repeat like Poxvirus_B22R_C PF13168.6 EAX83528.1 - 0.012 15.1 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF4116 PF13475.6 EAX83528.1 - 0.028 14.2 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX83528.1 - 0.27 11.6 6.7 38 4.7 0.1 4.1 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain SAS4 PF15460.6 EAX83528.1 - 4.5 7.4 13.0 12 6.1 0.2 3.8 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 KilA-N PF04383.13 EAX83529.1 - 1.2e-33 115.2 0.2 1.2e-33 115.2 0.2 2.0 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX83530.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83530.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX83530.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83530.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX83531.1 - 5.9e-153 507.2 13.6 7.4e-153 506.9 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83531.1 - 0.11 12.9 2.7 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83531.1 - 0.12 12.9 4.1 0.14 12.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX83532.1 - 2.7e-156 518.2 11.7 3.3e-156 517.9 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX83532.1 - 0.66 10.3 3.4 2.5 8.5 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX83532.1 - 0.74 10.3 6.8 2.4 8.7 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LRR_5 PF13306.6 EAX83533.1 - 4.2e-136 447.0 121.1 5.8e-32 110.3 10.6 7.0 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX83533.1 - 7.3e-31 105.7 25.8 0.00071 19.3 0.3 12.3 5 3 9 14 14 14 12 Leucine rich repeat LRR_4 PF12799.7 EAX83533.1 - 3.8 8.1 42.3 3 8.4 0.1 11.3 3 2 6 11 11 11 0 Leucine Rich repeats (2 copies) ARA70 PF12489.8 EAX83534.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF4107 PF13389.6 EAX83535.1 - 3.3e-66 222.4 14.1 8.2e-65 217.9 14.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX83536.1 - 0.042 14.3 0.5 0.081 13.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX83536.1 - 0.49 10.5 3.4 9.9 6.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein KilA-N PF04383.13 EAX83538.1 - 2.4e-41 140.1 0.1 2.4e-41 140.1 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX83538.1 - 0.0047 16.2 0.2 0.019 14.2 0.1 1.8 1 1 1 2 2 2 1 Acyl transferase DUF3213 PF11491.8 EAX83538.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX83538.1 - 0.065 11.8 0.1 0.1 11.1 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Glyco_transf_17 PF04724.13 EAX83539.1 - 1.1e-23 83.9 1.2 1.3e-23 83.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 JMY PF15871.5 EAX83541.1 - 0.008 15.5 0.4 0.012 15.0 0.4 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein HTH_11 PF08279.12 EAX83541.1 - 0.13 12.3 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 HTH domain DUF5065 PF16723.5 EAX83541.1 - 0.28 11.3 2.5 0.43 10.6 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4108 PF13390.6 EAX83542.1 - 2.9e-59 199.1 6.6 3.3e-59 198.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX83544.1 - 0.0013 18.6 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX83544.1 - 0.0027 18.0 0.0 0.0039 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83544.1 - 0.0034 17.7 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83544.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX83544.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX83544.1 - 0.042 13.4 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX83544.1 - 0.07 12.8 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX83544.1 - 0.14 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX83545.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83545.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX83545.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83545.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX83546.1 - 5.6e-35 119.6 0.6 1.1e-34 118.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX83547.1 - 1.4e-06 28.8 0.2 2.8e-06 27.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain T5orf172 PF10544.9 EAX83548.1 - 8.4e-05 23.1 0.3 0.00023 21.6 0.3 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83548.1 - 0.049 13.2 0.4 0.84 9.1 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX83549.1 - 1.5e-158 525.6 14.4 1.8e-158 525.3 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83549.1 - 0.11 13.0 2.7 0.26 11.7 0.5 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83549.1 - 0.46 11.0 7.3 2.4 8.7 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83549.1 - 0.69 10.5 6.0 0.22 12.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX83550.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX83554.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX83556.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83556.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX83557.1 - 1.4e-157 522.4 14.1 1.8e-157 522.1 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83557.1 - 0.067 13.8 6.2 0.12 12.9 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83557.1 - 1.3 9.5 8.0 2.1 8.8 1.0 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX83558.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83559.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Spo12 PF05032.12 EAX83562.1 - 0.2 11.6 5.5 0.16 11.9 2.9 2.1 2 1 0 2 2 2 0 Spo12 family Ank_2 PF12796.7 EAX83563.1 - 4.4e-79 261.1 62.7 2.5e-16 60.0 2.1 7.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83563.1 - 1.1e-64 214.0 24.2 1e-11 45.1 0.0 11.7 3 2 9 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX83563.1 - 9.1e-63 206.1 22.7 1.6e-07 31.5 0.3 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 EAX83563.1 - 5.8e-54 173.7 31.4 2e-05 24.6 0.2 12.2 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 EAX83563.1 - 3.6e-47 157.8 13.8 6.6e-11 42.2 0.1 7.4 6 3 2 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX83563.1 - 1.2e-37 127.6 8.0 1.2e-37 127.6 8.0 5.3 4 2 2 6 6 6 2 Domain of unknown function (DUF3447) MTES_1575 PF18741.1 EAX83563.1 - 0.0041 17.3 1.5 3.4 7.9 0.0 4.2 3 1 2 5 5 5 1 REase_MTES_1575 DHBP_synthase PF00926.19 EAX83563.1 - 0.08 12.5 4.8 1.5 8.3 0.3 3.6 3 1 1 4 4 4 0 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF5119 PF17145.4 EAX83563.1 - 0.17 11.9 2.2 0.38 10.7 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) RL PF17797.1 EAX83563.1 - 0.21 11.6 15.5 17 5.4 0.1 5.7 6 0 0 6 6 6 0 RL domain Ank PF00023.30 EAX83564.1 - 3.8e-59 194.7 0.0 3.4e-08 33.6 0.0 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 EAX83564.1 - 4.8e-58 192.5 9.6 7.6e-10 38.8 0.0 6.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX83564.1 - 2.4e-57 190.6 7.8 2.5e-09 37.5 0.0 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX83564.1 - 1.4e-42 144.1 12.1 1.5e-11 44.7 0.4 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX83564.1 - 5.1e-38 124.8 0.7 1.6e-05 24.9 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat MINDY_DUB PF04424.13 EAX83564.1 - 4e-05 23.6 2.0 5.9 6.9 0.0 3.9 1 1 3 4 4 4 2 MINDY deubiquitinase DUF1601 PF07671.11 EAX83564.1 - 0.00035 20.4 0.0 15 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) eRF1_1 PF03463.15 EAX83564.1 - 0.00048 20.1 1.1 23 5.0 0.0 4.5 1 1 4 5 5 5 0 eRF1 domain 1 zinc_ribbon_13 PF09855.9 EAX83564.1 - 0.00056 20.0 6.5 16 5.7 0.0 5.6 7 0 0 7 7 7 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) SAB PF04382.13 EAX83564.1 - 0.0014 18.7 0.4 98 3.1 0.0 4.6 4 0 0 4 4 4 0 SAB domain MetallophosN PF16371.5 EAX83564.1 - 0.0025 18.0 0.1 1.1e+02 3.1 0.0 5.1 1 1 2 5 5 5 0 N terminal of Calcineurin-like phosphoesterase DUF3718 PF12514.8 EAX83564.1 - 0.0057 16.8 0.9 49 4.2 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) B5 PF03484.15 EAX83564.1 - 0.0092 16.3 0.1 55 4.2 0.0 3.7 1 1 1 3 3 3 0 tRNA synthetase B5 domain DNA_meth_N PF18284.1 EAX83564.1 - 0.03 14.2 6.2 2.1e+02 1.9 0.0 6.2 7 0 0 7 7 7 0 DNA methylase N-terminal domain DUF348 PF03990.14 EAX83564.1 - 0.052 13.3 8.5 78 3.1 0.0 6.2 7 0 0 7 7 7 0 G5-linked-Ubiquitin-like domain DUF3895 PF13034.6 EAX83564.1 - 0.054 13.5 9.2 46 4.1 0.1 5.7 1 1 6 7 7 7 0 Protein of unknown function (DUF3895) MCC-bdg_PDZ PF10506.9 EAX83564.1 - 0.33 11.0 6.1 44 4.2 0.1 3.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AvrRpt-cleavage PF05627.11 EAX83564.1 - 1.3 8.4 11.9 43 3.6 0.2 4.3 4 0 0 4 4 4 0 Cleavage site for pathogenic type III effector avirulence factor Avr Ank PF00023.30 EAX83566.1 - 3.1e-53 176.0 10.9 1.7e-08 34.5 0.2 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 EAX83566.1 - 1.9e-52 175.8 29.6 8.2e-18 64.8 2.7 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83566.1 - 3.8e-47 158.1 14.6 2.9e-13 50.0 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX83566.1 - 2.9e-40 135.8 20.2 3.3e-09 36.8 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83566.1 - 5.9e-38 124.5 9.4 4e-05 23.7 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Peptidase_M16 PF00675.20 EAX83566.1 - 0.0026 17.7 4.0 0.31 11.0 0.2 3.6 1 1 1 3 3 3 1 Insulinase (Peptidase family M16) DUF3718 PF12514.8 EAX83566.1 - 0.011 15.8 4.6 21 5.4 0.2 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF3718) SNase PF00565.17 EAX83566.1 - 0.021 15.3 1.3 0.5 10.9 0.2 2.6 1 1 0 2 2 2 0 Staphylococcal nuclease homologue Fe-S_assembly PF04384.13 EAX83566.1 - 0.16 12.6 0.6 1.7e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 Iron-sulphur cluster assembly CCDC84 PF14968.6 EAX83566.1 - 0.58 9.7 4.7 12 5.4 0.3 3.5 1 1 3 4 4 4 0 Coiled coil protein 84 Trypan_PARP PF05887.11 EAX83568.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PapD_N PF00345.20 EAX83570.1 - 0.045 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX83570.1 - 0.07 13.1 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX83570.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX83570.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX83571.1 - 5.9e-16 58.6 3.3 8.8e-16 58.1 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX83572.1 - 3.7e-123 409.7 8.1 4.2e-123 409.5 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX83572.1 - 0.034 15.1 1.2 0.89 10.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) PA28_beta PF02252.18 EAX83572.1 - 0.12 12.1 3.6 0.35 10.5 1.2 2.4 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit PTR PF12789.7 EAX83573.1 - 3.7e-10 39.7 9.3 1e-08 35.1 5.6 4.3 5 0 0 5 5 5 2 Phage tail repeat like LIFR_D2 PF17971.1 EAX83573.1 - 0.063 13.5 0.0 6.5 7.0 0.0 2.3 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain EpuA PF11772.8 EAX83573.1 - 0.11 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta IL2 PF00715.17 EAX83573.1 - 0.44 10.5 3.1 7.2 6.5 0.1 2.5 3 0 0 3 3 3 0 Interleukin 2 DUF3839 PF12943.7 EAX83574.1 - 6.8e-81 271.3 10.4 8.8e-81 270.9 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83574.1 - 0.055 14.0 0.5 0.098 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Trypan_PARP PF05887.11 EAX83575.1 - 0.026 14.5 7.8 0.041 13.9 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mga PF05043.13 EAX83576.1 - 0.00086 19.9 0.1 0.0013 19.3 0.1 1.3 1 0 0 1 1 1 1 Mga helix-turn-helix domain Myb_DNA-binding PF00249.31 EAX83577.1 - 1.7e-30 104.9 0.4 2.8e-15 56.2 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX83577.1 - 1.3e-22 79.8 0.6 6.6e-15 55.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX83577.1 - 2.8e-05 23.9 0.8 9.3e-05 22.2 0.1 2.2 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX83577.1 - 0.0072 16.3 0.4 0.28 11.2 0.1 2.4 1 1 1 2 2 2 1 SLIDE MADF_DNA_bdg PF10545.9 EAX83577.1 - 0.03 14.6 0.5 0.14 12.5 0.1 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NLE PF08154.12 EAX83577.1 - 0.056 14.0 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain Polysacc_syn_2C PF08485.10 EAX83577.1 - 0.08 12.7 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Myb_DNA-bind_4 PF13837.6 EAX83577.1 - 0.14 12.5 1.5 0.43 11.0 0.1 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FCH PF00611.23 EAX83580.1 - 0.049 13.9 3.0 0.17 12.2 3.0 2.1 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF5344 PF17279.2 EAX83580.1 - 0.74 10.4 15.0 4.6 7.9 2.1 3.9 2 1 0 3 3 3 0 Family of unknown function (DUF5344) DUF4168 PF13767.6 EAX83580.1 - 0.74 11.0 12.9 1 10.6 4.5 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4168) HIP1_clath_bdg PF16515.5 EAX83580.1 - 1.5 9.4 17.8 0.88 10.2 0.9 3.3 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 EAX83580.1 - 2.2 7.5 7.6 6.5 6.0 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PSP PF04046.16 EAX83581.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83582.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX83582.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX83584.1 - 1.1e-156 519.4 13.4 1.4e-156 519.1 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83584.1 - 0.21 12.1 5.4 2 8.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX83585.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83585.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83585.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83585.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83585.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83585.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83585.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX83587.1 - 4.5e-157 520.7 14.4 5.6e-157 520.4 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX83587.1 - 0.033 14.2 2.3 6.3 6.8 0.0 2.9 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 EAX83587.1 - 0.075 13.5 2.3 0.12 12.9 0.5 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX83587.1 - 0.082 12.8 1.7 0.24 11.3 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83587.1 - 0.33 11.4 7.3 2.4 8.7 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX83588.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83588.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83588.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83588.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83588.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83588.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83588.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX83589.1 - 1.5e-156 519.0 13.5 1.9e-156 518.7 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83589.1 - 0.15 11.9 1.0 0.39 10.6 0.4 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX83589.1 - 0.19 12.3 5.4 0.5 10.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83589.1 - 0.21 12.1 6.4 2.1 8.8 1.0 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX83589.1 - 0.72 10.2 3.3 3.4 8.0 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain Tup_N PF08581.10 EAX83589.1 - 2.9 8.2 7.2 9.1 6.7 0.1 3.9 3 2 1 4 4 4 0 Tup N-terminal DUF4108 PF13390.6 EAX83590.1 - 6.6e-62 207.7 7.5 7.3e-62 207.5 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX83590.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX83592.1 - 7.5e-97 323.5 6.2 9.4e-97 323.2 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX83592.1 - 0.053 13.8 0.6 0.17 12.2 0.7 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF2897 PF11446.8 EAX83594.1 - 0.41 10.6 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX83595.1 - 1.7e-05 25.1 0.2 0.00013 22.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83595.1 - 1.8e-05 24.5 0.3 0.29 10.9 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83595.1 - 7.9e-05 22.7 3.1 0.00015 21.8 3.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83595.1 - 0.00038 20.3 0.1 0.0006 19.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83595.1 - 0.0012 18.7 1.0 0.0032 17.3 1.0 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX83595.1 - 0.0014 18.1 1.6 0.0014 18.1 1.6 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX83595.1 - 0.0092 16.3 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX83595.1 - 0.035 13.7 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX83595.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX83595.1 - 0.056 13.9 0.1 0.44 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83595.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83595.1 - 0.15 12.4 4.8 2.8 8.3 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX83595.1 - 0.22 11.2 0.0 0.22 11.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF4106 PF13388.6 EAX83596.1 - 5.3e-264 875.8 95.2 1.5e-140 469.2 33.9 5.3 3 1 2 5 5 5 3 Protein of unknown function (DUF4106) KAR PF15222.6 EAX83596.1 - 0.07 13.4 1.5 1.5 9.2 0.2 3.0 3 0 0 3 3 3 0 Kidney androgen-regulated DNA_pol_B_2 PF03175.13 EAX83597.1 - 8.1e-30 104.1 12.9 3.6e-29 102.0 12.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX83598.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX83598.1 - 0.087 12.8 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX83599.1 - 0.0052 17.2 0.7 0.0063 16.9 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83599.1 - 2.3 8.2 6.6 2.5 8.1 6.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX83600.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX83600.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal WASH-7_C PF14746.6 EAX83602.1 - 0.055 13.1 3.0 0.26 10.9 0.4 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX83602.1 - 0.23 11.7 5.6 0.73 10.1 5.6 1.8 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX83602.1 - 0.87 9.4 4.9 1.4 8.7 4.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PdaC PF13739.6 EAX83603.1 - 0.087 13.8 0.8 0.18 12.8 0.8 1.5 1 0 0 1 1 1 0 Deacetylase PdaC DUF613 PF04764.12 EAX83604.1 - 0.0038 17.3 0.1 0.051 13.7 0.1 3.0 1 0 0 1 1 1 1 Protein of unknown function (DUF613) Phage_hub_GP28 PF11110.8 EAX83605.1 - 0.09 12.7 1.2 0.23 11.4 0.3 1.9 2 1 0 2 2 2 0 Baseplate hub distal subunit DUF3839 PF12943.7 EAX83606.1 - 2.8e-153 508.3 12.6 3.4e-153 508.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83606.1 - 0.085 13.4 0.2 0.085 13.4 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MitMem_reg PF13012.6 EAX83606.1 - 0.13 12.6 0.4 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83606.1 - 1.1 9.7 6.3 2 8.9 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX83607.1 - 1.7e-11 44.0 0.1 3.5e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX83607.1 - 0.13 11.6 0.6 0.28 10.6 0.6 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain zf-Sec23_Sec24 PF04810.15 EAX83608.1 - 0.013 15.6 3.8 0.05 13.7 3.8 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger C6_DPF PF10170.9 EAX83608.1 - 0.027 14.8 1.7 0.046 14.1 1.7 1.4 1 0 0 1 1 1 0 Cysteine-rich domain Vps36-NZF-N PF16988.5 EAX83608.1 - 0.046 13.1 3.3 1.3 8.5 0.1 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF1272 PF06906.11 EAX83608.1 - 0.051 13.7 0.9 0.098 12.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) KilA-N PF04383.13 EAX83609.1 - 3.8e-10 39.6 0.9 5.5e-10 39.1 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF2313 PF10076.9 EAX83609.1 - 0.043 13.7 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF3839 PF12943.7 EAX83610.1 - 4.7e-126 419.2 7.4 5.4e-126 418.9 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX83610.1 - 0.04 13.4 0.9 0.06 12.8 0.9 1.5 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX83610.1 - 0.11 13.1 1.4 0.37 11.4 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX83610.1 - 0.31 11.3 3.9 4.4 7.6 0.0 3.1 2 1 1 3 3 3 0 Rx N-terminal domain CHASE3 PF05227.13 EAX83612.1 - 0.01 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 CHASE3 domain DUF3685 PF12452.8 EAX83612.1 - 0.055 13.2 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) GPS2_interact PF15784.5 EAX83613.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83613.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83614.1 - 0.018 15.0 9.1 0.025 14.6 9.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83614.1 - 9.3 6.7 7.5 14 6.1 7.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin T5orf172 PF10544.9 EAX83615.1 - 4.1e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX83616.1 - 1.3e-36 126.5 15.6 7.1e-36 124.1 15.6 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX83617.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX83617.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PTR PF12789.7 EAX83618.1 - 4.1e-30 103.6 10.9 4.1e-30 103.6 10.9 4.0 4 1 1 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX83618.1 - 0.05 13.3 0.2 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX83618.1 - 4.1 7.4 8.7 2.7 7.9 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAX83618.1 - 9.9 5.7 21.2 11 5.5 5.1 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX83619.1 - 0.01 16.3 1.1 0.016 15.6 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX83620.1 - 4e-26 92.0 3.9 5.8e-26 91.4 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ResIII PF04851.15 EAX83621.1 - 3.5e-05 23.9 1.1 5.8e-05 23.1 1.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83621.1 - 0.00017 21.4 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX83621.1 - 0.00035 20.8 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX83621.1 - 0.00095 19.0 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83621.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX83621.1 - 0.026 14.0 0.0 0.037 13.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX83621.1 - 0.027 14.1 0.4 0.044 13.5 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX83621.1 - 0.096 12.3 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX83621.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX83621.1 - 0.19 11.4 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4108 PF13390.6 EAX83623.1 - 2.1e-61 206.0 7.3 2.4e-61 205.9 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX83624.1 - 7.2e-05 23.2 2.2 0.00052 20.4 2.2 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX83624.1 - 0.089 13.4 0.2 0.18 12.4 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PTR PF12789.7 EAX83625.1 - 2.5e-06 27.5 36.0 5.6e-05 23.1 2.3 7.1 5 3 1 6 6 6 4 Phage tail repeat like DUF4795 PF16043.5 EAX83625.1 - 0.0007 19.2 27.8 1.4 8.5 0.7 4.9 3 1 2 5 5 5 5 Domain of unknown function (DUF4795) Pox_A32 PF04665.12 EAX83626.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83626.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83626.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83626.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83626.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83626.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83626.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83626.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83626.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83626.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83626.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83626.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX83627.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF4108 PF13390.6 EAX83628.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX83628.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide T5orf172 PF10544.9 EAX83630.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83631.1 - 5.6e-35 119.6 0.6 1.1e-34 118.7 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83631.1 - 0.011 16.3 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX83631.1 - 0.94 9.5 4.1 2.8 8.0 0.4 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX83632.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83632.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83632.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83632.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83632.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83632.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83632.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83632.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83632.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83632.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83632.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83632.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX83634.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83634.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX83635.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX83636.1 - 2.6e-154 511.7 13.0 3.4e-154 511.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83636.1 - 1.1 9.8 5.2 1.8 9.0 0.7 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83637.1 - 4.3e-157 520.8 14.2 5.3e-157 520.5 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX83637.1 - 0.17 11.4 3.7 0.13 11.7 0.5 2.2 1 1 1 2 2 2 0 Z1 domain DUF2408 PF10303.9 EAX83637.1 - 0.29 11.7 4.1 0.28 11.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83637.1 - 0.31 11.5 5.8 0.76 10.3 0.3 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX83637.1 - 0.47 10.8 3.7 14 6.0 0.0 3.8 4 1 0 4 4 4 0 Tup N-terminal Rx_N PF18052.1 EAX83637.1 - 0.8 10.0 4.1 2.8 8.3 0.1 3.2 2 2 0 2 2 2 0 Rx N-terminal domain DUF4107 PF13389.6 EAX83640.1 - 1.5e-70 236.6 3.2 2e-70 236.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX83642.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX83644.1 - 2.2e-157 521.7 15.0 2.8e-157 521.4 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83644.1 - 0.044 14.4 5.5 0.25 11.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX83644.1 - 0.11 12.4 1.3 0.32 10.8 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Fez1 PF06818.15 EAX83644.1 - 0.14 12.6 2.5 0.15 12.5 0.5 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83644.1 - 0.5 10.8 8.3 2.1 8.9 1.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83645.1 - 0.00017 22.1 0.7 0.00044 20.7 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX83645.1 - 0.068 13.0 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KilA-N domain DUF3148 PF11347.8 EAX83645.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) DUF3839 PF12943.7 EAX83646.1 - 5.9e-144 477.8 13.2 7.6e-144 477.4 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83646.1 - 0.16 11.8 1.1 0.5 10.2 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83646.1 - 0.36 11.3 4.8 1.7 9.1 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83647.1 - 1e-06 29.2 0.1 2.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83647.1 - 0.13 11.8 0.2 0.67 9.4 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83648.1 - 2.4e-32 111.1 0.3 5.9e-32 109.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Myb_DNA-binding PF00249.31 EAX83649.1 - 0.03 14.5 0.1 4.4 7.6 0.1 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain Gag_p10 PF02337.17 EAX83649.1 - 0.038 13.9 0.9 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 Retroviral GAG p10 protein TSP_NTD PF17804.1 EAX83649.1 - 0.07 13.4 1.0 0.099 12.9 1.0 1.3 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Retrotrans_gag PF03732.17 EAX83649.1 - 0.57 10.5 2.8 7.1 7.0 0.4 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein KilA-N PF04383.13 EAX83650.1 - 2.1e-45 153.2 0.1 2.1e-45 153.2 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83650.1 - 0.012 15.8 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Hormone_1 PF00103.20 EAX83650.1 - 1 9.1 5.3 7.3 6.3 0.2 2.1 1 1 1 2 2 2 0 Somatotropin hormone family DUF3839 PF12943.7 EAX83651.1 - 7.5e-151 500.3 13.6 9.7e-151 500.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83651.1 - 0.03 14.8 1.3 0.19 12.2 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83651.1 - 0.59 10.6 5.1 4.8 7.7 0.4 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX83651.1 - 1.6 9.1 4.8 1.2 9.5 1.3 2.5 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX83651.1 - 2.1 8.6 5.4 4.4 7.6 0.3 3.5 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX83651.1 - 3.3 8.3 5.9 1.8 9.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) GPS2_interact PF15784.5 EAX83652.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83652.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pox_A32 PF04665.12 EAX83654.1 - 3.6e-07 29.9 5.6 4.1e-07 29.7 3.7 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83654.1 - 2.6e-05 24.5 0.1 0.00017 21.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83654.1 - 5.9e-05 22.9 0.2 0.39 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83654.1 - 0.00058 19.9 3.4 0.0013 18.8 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX83654.1 - 0.0019 18.1 0.3 0.0059 16.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83654.1 - 0.0021 17.7 0.4 0.016 14.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) DEAD PF00270.29 EAX83654.1 - 0.0024 17.7 0.1 0.0044 16.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX83654.1 - 0.016 15.6 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX83654.1 - 0.06 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX83654.1 - 0.079 12.5 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX83654.1 - 0.09 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83654.1 - 0.3 11.3 3.3 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83655.1 - 7.5e-152 503.6 14.7 9.9e-152 503.2 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83655.1 - 0.041 14.3 1.9 0.11 12.9 0.2 2.0 2 0 0 2 2 2 0 Fez1 Glu-tRNAGln PF02686.15 EAX83655.1 - 1.1 9.6 3.5 0.95 9.8 0.5 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX83655.1 - 1.8 9.1 8.6 3.3 8.2 1.3 3.4 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83655.1 - 5 7.7 6.7 2.7 8.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Spo12 PF05032.12 EAX83656.1 - 0.24 11.3 6.2 0.17 11.8 2.9 2.3 2 1 0 2 2 2 0 Spo12 family DUF4107 PF13389.6 EAX83658.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX83658.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX83659.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase FAS_N PF17828.1 EAX83660.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX83661.1 - 0.034 14.1 8.6 0.053 13.5 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83661.1 - 0.86 10.1 4.9 1.2 9.5 4.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX83662.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX83662.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX83663.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX83665.1 - 0.091 13.2 1.6 0.12 12.8 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83665.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83666.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4108 PF13390.6 EAX83667.1 - 2.1e-57 193.1 4.0 2.4e-57 192.9 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX83667.1 - 0.11 11.6 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX83668.1 - 1.5e-06 27.8 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Trypan_PARP PF05887.11 EAX83669.1 - 0.031 14.3 8.5 0.041 13.9 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83669.1 - 1.9 9.0 5.6 2.4 8.6 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX83670.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX83672.1 - 4.8e-157 520.6 14.0 6.1e-157 520.3 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX83672.1 - 0.072 13.3 1.2 0.14 12.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF29 MitMem_reg PF13012.6 EAX83672.1 - 0.072 13.5 0.7 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83672.1 - 0.39 11.2 5.5 2 8.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX83672.1 - 0.6 10.4 0.1 0.6 10.4 0.1 3.2 4 1 0 4 4 4 0 PRD domain T5orf172 PF10544.9 EAX83673.1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83673.1 - 0.069 13.0 0.1 0.39 10.6 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain MULE PF10551.9 EAX83675.1 - 6.7e-05 23.2 1.9 8.5e-05 22.9 0.5 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX83675.1 - 0.0084 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DUF1493 PF07377.12 EAX83676.1 - 0.078 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX83679.1 - 4.6e-155 514.1 12.5 5.8e-155 513.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83679.1 - 0.17 11.8 1.4 0.53 10.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX83679.1 - 0.21 11.9 3.4 1.3 9.3 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX83679.1 - 0.62 10.5 6.0 4.3 7.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX83679.1 - 1.9 8.8 4.7 1.2 9.4 1.2 2.4 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Ras PF00071.22 EAX83680.1 - 1.6e-51 174.1 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX83680.1 - 2.6e-22 79.3 0.0 3.8e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX83680.1 - 2.8e-08 33.4 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX83680.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX83680.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Apolipoprotein PF01442.18 EAX83682.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4108 PF13390.6 EAX83685.1 - 1.5e-58 196.8 7.2 1.7e-58 196.6 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Spo12 PF05032.12 EAX83688.1 - 0.21 11.5 5.5 0.17 11.8 2.9 2.1 2 1 0 2 2 2 0 Spo12 family KilA-N PF04383.13 EAX83689.1 - 2.8e-40 136.7 2.0 3.4e-40 136.4 0.6 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83689.1 - 0.027 14.6 0.4 0.07 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX83690.1 - 2.2e-06 28.1 0.2 5.1e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83690.1 - 0.018 14.8 2.9 0.069 13.0 0.9 2.7 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX83690.1 - 0.02 14.4 0.6 0.23 11.0 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain FRG PF08867.11 EAX83690.1 - 0.034 15.1 0.1 1.2 10.1 0.0 2.2 2 0 0 2 2 2 0 FRG domain DUF3839 PF12943.7 EAX83691.1 - 2.4e-81 272.7 10.2 3.1e-81 272.4 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83691.1 - 0.042 14.4 0.3 0.074 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) GalP_UDP_transf PF01087.22 EAX83691.1 - 0.31 11.4 1.7 1.6 9.1 1.0 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF745 PF05335.13 EAX83692.1 - 0.0025 17.6 14.3 0.0064 16.2 13.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 EAX83692.1 - 0.0047 17.1 23.0 0.078 13.1 4.3 2.3 1 1 1 2 2 2 2 Tropomyosin like AphA_like PF14557.6 EAX83692.1 - 0.01 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator SesA PF17107.5 EAX83692.1 - 0.012 15.8 5.8 0.012 15.8 5.8 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HTH_18 PF12833.7 EAX83692.1 - 0.017 15.4 3.1 0.021 15.1 1.7 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain Cast PF10174.9 EAX83692.1 - 0.017 13.4 20.1 0.022 13.0 20.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.19 EAX83692.1 - 0.032 12.1 21.4 0.04 11.7 21.4 1.0 1 0 0 1 1 1 0 Myosin tail Golgin_A5 PF09787.9 EAX83692.1 - 0.043 13.3 25.3 0.025 14.1 22.9 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 SKA1 PF07160.12 EAX83692.1 - 0.083 12.7 15.2 0.18 11.6 13.9 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Lebercilin PF15619.6 EAX83692.1 - 0.12 12.0 23.4 2.2 7.9 23.4 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 EAX83692.1 - 0.21 11.8 21.9 0.11 12.7 12.6 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EAX83692.1 - 0.27 11.3 5.4 4.1 7.4 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 EAX83692.1 - 0.36 10.9 24.6 1.5 8.9 1.3 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 EAX83692.1 - 0.47 10.4 0.1 0.47 10.4 0.1 3.8 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GrpE PF01025.19 EAX83692.1 - 0.55 9.9 18.2 1.2 8.8 1.5 2.8 1 1 2 3 3 3 0 GrpE SlyX PF04102.12 EAX83692.1 - 0.55 10.9 18.5 1.7 9.4 1.3 4.7 1 1 4 5 5 5 0 SlyX Tropomyosin PF00261.20 EAX83692.1 - 0.57 9.5 22.7 1.5 8.1 1.5 3.2 1 1 1 3 3 3 0 Tropomyosin PCRF PF03462.18 EAX83692.1 - 0.86 9.4 12.0 0.85 9.5 10.1 1.8 1 1 1 2 2 2 0 PCRF domain CTU2 PF10288.9 EAX83692.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.8 1 1 1 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Spc7 PF08317.11 EAX83692.1 - 1.3 7.9 24.2 0.3 9.9 13.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2400 PF09674.10 EAX83692.1 - 1.6 8.7 12.8 0.055 13.4 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) ADIP PF11559.8 EAX83692.1 - 1.9 8.5 25.3 34 4.5 14.4 3.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 EAX83692.1 - 2.3 8.6 18.9 0.26 11.6 9.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 EAX83692.1 - 2.4 8.5 26.8 0.049 13.9 10.6 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 Csm1_N PF18504.1 EAX83692.1 - 2.4 8.6 21.9 1.3 9.4 1.6 4.3 4 1 1 5 5 4 0 Csm1 N-terminal domain APG6_N PF17675.1 EAX83692.1 - 2.8 8.5 25.8 9.1 6.8 23.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Peptidase_S46 PF10459.9 EAX83692.1 - 3 6.4 9.9 3.3 6.2 9.9 1.1 1 0 0 1 1 1 0 Peptidase S46 TMF_TATA_bd PF12325.8 EAX83692.1 - 4.3 7.6 21.1 13 6.1 17.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding USP8_interact PF08941.10 EAX83692.1 - 6.4 6.6 9.3 2.2 8.1 3.1 2.3 1 1 1 2 2 2 0 USP8 interacting Bap31_Bap29_C PF18035.1 EAX83692.1 - 7.4 6.7 10.6 0.65 10.0 0.7 3.3 2 2 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 EAX83692.1 - 9.5 5.5 15.4 32 3.8 14.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EAX83692.1 - 9.7 6.7 11.1 3.5 8.1 0.2 4.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF3839 PF12943.7 EAX83693.1 - 2.7e-143 475.6 10.1 3.1e-143 475.4 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83693.1 - 0.12 12.8 2.0 1.4 9.4 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX83694.1 - 3.4e-157 521.1 11.5 4.2e-157 520.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX83694.1 - 0.077 13.3 1.6 9.2 6.7 0.1 3.6 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX83694.1 - 0.093 13.2 4.6 2.1 8.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX83695.1 - 1.6e-22 79.5 0.2 3e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX83695.1 - 0.051 13.6 1.2 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NTS PF15447.6 EAX83695.1 - 0.059 13.9 0.4 0.15 12.5 0.4 1.8 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 DUF4541 PF15074.6 EAX83696.1 - 0.069 13.8 0.2 0.14 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) TMP PF05017.14 EAX83697.1 - 0.046 14.3 4.9 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83698.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Apolipoprotein PF01442.18 EAX83699.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TRAM_LAG1_CLN8 PF03798.16 EAX83701.1 - 1.2e-19 70.9 13.9 1.9e-19 70.2 13.9 1.3 1 0 0 1 1 1 1 TLC domain UCH PF00443.29 EAX83703.1 - 1.6e-06 27.8 0.3 1.9e-06 27.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX83703.1 - 0.0044 16.6 0.1 0.0057 16.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A32 PF04665.12 EAX83704.1 - 3.9e-07 29.8 0.2 4.6e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein GAGA_bind PF06217.12 EAX83705.1 - 0.019 15.3 3.0 0.023 15.0 3.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Btz PF09405.10 EAX83705.1 - 0.066 13.5 8.2 0.12 12.6 8.2 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF4108 PF13390.6 EAX83706.1 - 1.5e-57 193.5 5.5 1.7e-57 193.4 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX83706.1 - 0.2 11.9 0.9 7.6 6.9 0.3 2.5 2 1 1 3 3 3 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX83707.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF3839 PF12943.7 EAX83708.1 - 2.7e-68 230.0 4.9 3.7e-68 229.6 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX83708.1 - 0.17 12.5 1.4 0.29 11.7 1.4 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr KilA-N PF04383.13 EAX83709.1 - 2.7e-33 114.2 1.2 3.8e-33 113.7 0.1 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX83709.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX83710.1 - 1e-05 26.0 0.2 2.5e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83710.1 - 0.00098 19.0 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX83710.1 - 0.14 11.7 0.4 9.4 5.7 0.1 2.1 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX83711.1 - 4.1e-156 517.6 11.3 5.2e-156 517.2 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83711.1 - 0.21 12.1 4.3 4.3 7.9 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83711.1 - 0.93 10.1 5.5 0.31 11.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX83711.1 - 4.6 7.6 7.5 14 6.1 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal DUF3839 PF12943.7 EAX83712.1 - 7e-153 507.0 13.2 8.3e-153 506.7 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83712.1 - 1.8 9.1 8.8 1.6 9.2 0.6 3.1 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83713.1 - 1.8e-07 31.7 0.3 3.5e-07 30.7 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX83714.1 - 2e-108 361.4 5.2 2.3e-108 361.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX83714.1 - 0.045 13.2 0.5 0.066 12.7 0.4 1.3 1 1 0 1 1 1 0 Z1 domain MULE PF10551.9 EAX83715.1 - 1.4e-10 41.5 0.2 3.8e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX83715.1 - 0.024 13.5 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family MULE PF10551.9 EAX83716.1 - 1.9e-11 44.2 0.6 5.6e-11 42.7 0.6 1.9 1 0 0 1 1 1 1 MULE transposase domain CREPT PF16566.5 EAX83716.1 - 0.025 14.7 2.9 0.31 11.2 0.3 2.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DDE_Tnp_ISL3 PF01610.17 EAX83716.1 - 0.045 13.5 0.8 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Transposase X8 PF07983.13 EAX83716.1 - 0.065 13.9 0.4 2.7 8.8 0.2 2.6 2 0 0 2 2 2 0 X8 domain L27_1 PF09058.10 EAX83716.1 - 0.084 12.9 5.3 0.26 11.3 0.0 3.5 3 1 0 3 3 3 0 L27_1 Transposase_mut PF00872.18 EAX83716.1 - 0.087 11.7 1.0 0.18 10.6 1.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX83717.1 - 3.4e-155 514.6 13.1 4.2e-155 514.3 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83717.1 - 0.063 13.1 1.9 0.14 12.0 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX83717.1 - 0.5 10.7 3.3 1.6 9.1 0.0 3.1 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX83717.1 - 1.1 9.8 7.5 3.4 8.2 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX83717.1 - 2.4 8.5 6.1 12 6.2 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX83719.1 - 1.5e-06 28.7 0.1 4.6e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX83719.1 - 0.023 14.6 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX83719.1 - 0.051 13.1 0.2 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain LIF_OSM PF01291.17 EAX83720.1 - 0.032 14.4 0.8 0.08 13.1 0.0 2.0 3 0 0 3 3 3 0 LIF / OSM family DUF3781 PF12636.7 EAX83721.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX83722.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83722.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83723.1 - 0.076 13.0 13.2 0.078 13.0 13.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83723.1 - 4.5 7.7 8.2 5.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PSP PF04046.16 EAX83725.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX83726.1 - 1.4e-155 515.8 12.7 1.8e-155 515.4 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83726.1 - 0.017 15.6 0.9 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83726.1 - 0.15 12.5 5.5 2.2 8.8 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83726.1 - 0.83 10.2 4.8 0.6 10.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX83728.1 - 0.11 13.2 7.1 6.5 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83729.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX83730.1 - 2.3e-15 56.4 17.6 1.3e-09 38.0 4.3 4.4 5 0 0 5 5 5 2 Phage tail repeat like EpuA PF11772.8 EAX83730.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF5082 PF16888.5 EAX83730.1 - 8.8 6.6 16.1 15 5.8 2.8 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 EAX83730.1 - 9.3 6.2 9.8 4.6 7.1 1.8 3.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF3839 PF12943.7 EAX83731.1 - 5.6e-158 523.7 13.9 6.9e-158 523.4 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83731.1 - 3 8.4 8.1 1.5 9.3 0.5 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83732.1 - 3.4e-06 27.6 0.4 9.2e-06 26.1 0.1 1.9 2 1 0 2 2 2 1 T5orf172 domain Pox_A32 PF04665.12 EAX83733.1 - 2e-07 30.8 2.4 2e-07 30.7 1.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83733.1 - 0.004 16.8 0.1 0.0052 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83733.1 - 0.042 13.4 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83733.1 - 0.059 13.1 0.2 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83733.1 - 0.077 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83733.1 - 0.16 11.9 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83733.1 - 0.34 11.1 8.5 5.3 7.3 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX83734.1 - 4.3e-07 29.6 2.6 6.8e-07 29.0 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83734.1 - 4e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83734.1 - 0.00017 21.9 0.1 0.0012 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83734.1 - 0.00098 19.2 3.7 0.0024 17.9 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83734.1 - 0.0032 17.2 0.1 0.0059 16.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83734.1 - 0.0049 16.7 0.3 0.0097 15.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83734.1 - 0.0054 16.4 0.1 0.0095 15.6 0.1 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83734.1 - 0.05 13.9 0.0 0.097 13.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX83734.1 - 0.1 13.1 0.1 0.83 10.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX83734.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX83735.1 - 1.7e-154 512.2 12.9 2.1e-154 512.0 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83735.1 - 0.019 15.4 1.5 0.098 13.1 0.2 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX83735.1 - 0.061 13.6 1.4 7 7.0 0.2 3.6 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX83735.1 - 0.42 11.1 7.1 2 8.9 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX83736.1 - 1.5e-32 113.0 4.0 1.9e-32 112.7 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pkinase PF00069.25 EAX83737.1 - 6.6e-27 94.5 0.0 7.4e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX83737.1 - 2.6e-12 46.6 0.0 3e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX83737.1 - 0.0034 16.7 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX83737.1 - 0.025 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EAX83737.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX83737.1 - 0.088 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAX83738.1 - 3.7e-43 147.8 0.2 4.8e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX83738.1 - 2.1e-22 79.7 0.1 2.5e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX83738.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX83738.1 - 0.02 14.3 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX83738.1 - 0.022 14.4 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DUF3839 PF12943.7 EAX83739.1 - 5.9e-158 523.6 12.8 7.4e-158 523.3 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83739.1 - 0.16 12.5 4.5 2 8.9 0.0 3.4 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83739.1 - 0.55 10.8 5.5 0.14 12.7 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX83739.1 - 0.63 10.4 4.1 12 6.3 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal DUF3839 PF12943.7 EAX83740.1 - 1.2e-145 483.4 12.0 1.5e-145 483.0 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83740.1 - 0.074 13.5 0.2 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX83740.1 - 0.53 10.8 5.5 4.6 7.8 0.2 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX83740.1 - 1.4 9.3 5.3 13 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX83741.1 - 1.1e-06 29.1 0.1 2.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83741.1 - 0.016 15.1 0.3 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 KilA-N domain Aa_trans PF01490.18 EAX83742.1 - 8.5e-10 37.9 40.6 1.2e-09 37.4 40.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pox_A32 PF04665.12 EAX83743.1 - 8.1e-07 28.7 2.5 8.1e-07 28.7 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83743.1 - 3.3e-05 23.7 0.3 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83743.1 - 4.5e-05 23.7 0.2 0.00032 21.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83743.1 - 0.00056 20.0 5.0 0.001 19.1 4.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83743.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83743.1 - 0.0023 17.7 1.1 0.0041 17.0 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83743.1 - 0.0065 16.1 2.9 0.016 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83743.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX83743.1 - 0.086 12.9 0.7 1.3 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX83743.1 - 0.091 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83743.1 - 0.11 13.0 0.1 0.94 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83743.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83743.1 - 0.6 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX83743.1 - 0.71 10.6 11.7 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 KilA-N PF04383.13 EAX83744.1 - 3.5e-42 142.8 1.1 5.4e-42 142.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83744.1 - 0.0075 16.9 0.7 0.022 15.4 0.0 2.1 3 0 0 3 3 3 1 Parathyroid hormone family PTPRCAP PF15713.5 EAX83744.1 - 0.92 9.8 7.2 2.2 8.6 0.3 2.3 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated KilA-N PF04383.13 EAX83745.1 - 6.8e-31 106.4 0.1 1.1e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DDR PF08841.10 EAX83746.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX83746.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4108 PF13390.6 EAX83747.1 - 1.8e-63 212.7 6.9 2e-63 212.6 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX83749.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83749.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83749.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83749.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83749.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83749.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83749.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83749.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83749.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83749.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83749.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83749.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX83750.1 - 1.1e-40 138.0 0.8 2e-40 137.1 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83750.1 - 0.025 15.2 0.0 0.078 13.6 0.0 1.8 1 0 0 1 1 1 0 Parathyroid hormone family ANAPC4_WD40 PF12894.7 EAX83751.1 - 3.4e-10 40.1 1.1 0.00024 21.4 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX83751.1 - 2.2e-06 28.3 7.6 0.00047 20.9 0.1 4.5 4 1 1 5 5 5 2 WD domain, G-beta repeat PHTB1_N PF14727.6 EAX83751.1 - 1.1e-05 24.9 0.2 0.22 10.8 0.0 3.0 1 1 2 3 3 3 2 PTHB1 N-terminus Peptidase_M23 PF01551.22 EAX83751.1 - 0.071 13.3 0.2 1.4 9.1 0.0 2.9 2 1 1 3 3 3 0 Peptidase family M23 Ank_2 PF12796.7 EAX83752.1 - 6.4e-43 145.2 16.1 2.9e-16 59.8 1.4 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX83752.1 - 2.7e-40 135.1 0.7 5.7e-08 32.9 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX83752.1 - 1.7e-36 123.8 12.2 4.6e-12 45.9 0.2 3.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX83752.1 - 4.8e-35 119.5 2.4 2.9e-11 43.7 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83752.1 - 8.1e-29 96.5 1.1 1.5e-05 25.0 0.0 5.3 5 1 0 5 5 5 4 Ankyrin repeat WYL PF13280.6 EAX83752.1 - 0.015 15.4 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 WYL domain Shigella_OspC PF06128.11 EAX83752.1 - 0.016 14.9 0.9 4.7 6.8 0.0 2.9 2 1 1 3 3 3 0 Shigella flexneri OspC protein MCC-bdg_PDZ PF10506.9 EAX83752.1 - 0.024 14.6 1.6 4.6 7.3 0.3 3.6 2 1 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome BRCT_2 PF16589.5 EAX83752.1 - 0.058 13.8 1.4 10 6.6 0.1 3.1 1 1 2 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain DUF3839 PF12943.7 EAX83753.1 - 3.4e-155 514.6 11.9 3.9e-155 514.4 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83753.1 - 0.12 12.3 0.4 0.29 11.0 0.2 1.7 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83753.1 - 0.27 11.7 3.5 0.5 10.9 0.6 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 EAX83754.1 - 7.4e-33 113.0 22.7 3.7e-14 53.1 1.8 5.6 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83754.1 - 8.4e-30 102.8 10.2 2.6e-09 37.4 0.3 7.1 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX83754.1 - 1.3e-26 91.8 13.4 4.2e-05 23.8 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 EAX83754.1 - 1.6e-23 82.4 5.2 1.6e-23 82.4 5.2 4.4 4 2 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX83754.1 - 3e-20 72.0 8.4 1.3e-05 25.3 0.1 5.3 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83754.1 - 5.3e-19 66.3 14.1 0.0023 18.3 0.2 9.5 9 0 0 9 9 9 4 Ankyrin repeat CbiA PF01656.23 EAX83754.1 - 0.0011 19.0 0.1 0.0028 17.7 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MULE PF10551.9 EAX83755.1 - 1.4e-10 41.4 2.2 5.3e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX83755.1 - 0.002 18.2 1.1 0.0067 16.5 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX83755.1 - 0.0049 15.8 0.3 0.0085 15.0 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF4108 PF13390.6 EAX83757.1 - 7.3e-43 145.9 2.9 8e-43 145.8 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX83757.1 - 0.14 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF2897 PF11446.8 EAX83758.1 - 0.52 10.2 3.5 0.85 9.6 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX83759.1 - 2.6e-62 209.0 7.7 2.9e-62 208.8 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX83760.1 - 1.5e-43 147.2 0.6 3.2e-43 146.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX83760.1 - 0.12 12.4 6.3 0.23 11.4 6.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Hormone_1 PF00103.20 EAX83760.1 - 0.3 10.8 4.7 4.4 7.0 0.6 2.2 2 0 0 2 2 2 0 Somatotropin hormone family DUF3839 PF12943.7 EAX83761.1 - 6.1e-152 503.9 15.5 7.6e-152 503.6 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83761.1 - 0.13 12.7 2.2 0.4 11.1 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83761.1 - 0.26 11.8 4.7 4.8 7.7 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX83761.1 - 0.32 11.3 3.2 0.66 10.3 0.1 2.8 2 2 0 2 2 2 0 Rx N-terminal domain DUF2408 PF10303.9 EAX83761.1 - 1.6 9.3 6.3 0.55 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX83762.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX83764.1 - 8.7e-05 22.6 3.2 0.00016 21.7 3.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX83764.1 - 0.00024 21.4 0.0 0.00054 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX83764.1 - 0.00038 20.3 0.0 0.00051 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83764.1 - 0.00085 19.2 1.1 0.0025 17.6 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83764.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83764.1 - 0.014 15.2 0.2 0.22 11.2 0.0 2.1 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAX83764.1 - 0.045 13.2 0.0 0.062 12.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX83764.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX83764.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX83764.1 - 0.19 12.0 4.3 4.9 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) CTU2 PF10288.9 EAX83765.1 - 0.067 13.4 0.1 0.21 11.9 0.0 1.7 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF842 PF05811.13 EAX83765.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF4061 PF13270.6 EAX83765.1 - 0.15 12.4 2.6 0.2 12.0 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) SlyX PF04102.12 EAX83765.1 - 0.43 11.2 2.4 5.9 7.6 0.6 2.2 1 1 1 2 2 2 0 SlyX DUF3839 PF12943.7 EAX83766.1 - 1.1e-156 519.5 15.1 1.4e-156 519.1 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83766.1 - 0.052 14.0 2.2 0.076 13.5 0.4 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX83766.1 - 0.13 12.1 1.9 0.27 11.1 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83766.1 - 0.46 11.0 5.8 5 7.6 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX83766.1 - 2.7 8.4 6.4 12 6.3 0.1 3.6 4 1 1 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX83767.1 - 4.8e-07 30.3 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83767.1 - 0.053 13.4 2.7 0.16 11.8 0.8 2.5 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX83767.1 - 0.095 12.2 0.8 0.38 10.2 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain PDEase_I PF00233.19 EAX83768.1 - 1.3e-43 149.5 0.1 2.4e-43 148.6 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX83768.1 - 2e-08 34.9 0.0 3.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EAX83768.1 - 7.3e-08 32.8 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EAX83768.1 - 1.3e-05 25.6 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain DUF676 PF05057.14 EAX83769.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3839 PF12943.7 EAX83770.1 - 1.5e-77 260.4 11.6 1.8e-77 260.1 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83770.1 - 0.074 12.9 2.0 0.23 11.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX83770.1 - 0.075 13.3 0.4 0.22 11.8 0.4 2.0 1 1 0 1 1 1 0 Rx N-terminal domain PRD PF00874.20 EAX83770.1 - 0.098 13.0 1.0 0.5 10.7 0.1 2.4 2 1 1 3 3 3 0 PRD domain LD_cluster2 PF18163.1 EAX83770.1 - 0.14 11.7 0.5 0.8 9.2 0.0 2.2 2 1 1 3 3 3 0 SLOG cluster2 Mito_fiss_reg PF05308.11 EAX83771.1 - 0.15 12.1 0.9 0.16 12.0 0.9 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX83771.1 - 2 7.8 3.9 2 7.8 3.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Snf7 PF03357.21 EAX83772.1 - 6.8e-20 71.4 17.1 7.9e-20 71.1 17.1 1.0 1 0 0 1 1 1 1 Snf7 SF-assemblin PF06705.11 EAX83772.1 - 0.0043 16.4 5.4 0.0064 15.9 5.4 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF2854 PF11016.8 EAX83772.1 - 0.064 13.2 0.4 0.14 12.1 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2854) Spc24 PF08286.11 EAX83772.1 - 0.17 12.1 10.3 0.16 12.2 4.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PYRIN PF02758.16 EAX83772.1 - 0.61 10.3 4.9 0.2 11.9 0.7 2.3 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain COG2 PF06148.11 EAX83772.1 - 1.3 9.1 5.5 1.6 8.8 4.3 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1479 PF07350.12 EAX83772.1 - 4.8 5.8 6.3 1.7 7.4 3.6 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) PSP PF04046.16 EAX83773.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX83774.1 - 0.029 14.9 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX83776.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX83776.1 - 0.16 12.5 0.4 0.38 11.2 0.4 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF5065 PF16723.5 EAX83777.1 - 1.1 9.3 3.7 20 5.2 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) Trypan_PARP PF05887.11 EAX83778.1 - 0.042 13.8 12.0 0.043 13.8 12.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83778.1 - 2.7 8.4 6.8 3 8.3 6.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX83779.1 - 0.056 13.9 1.4 0.075 13.5 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83779.1 - 0.057 12.4 0.1 0.059 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX83781.1 - 1.9e-80 269.8 10.7 2.4e-80 269.5 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MciZ PF13072.6 EAX83781.1 - 1 9.2 4.1 68 3.4 0.1 3.6 2 1 2 4 4 4 0 Mother cell inhibitor of FtsZ Trypan_PARP PF05887.11 EAX83783.1 - 0.12 12.3 9.1 0.15 12.1 9.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83783.1 - 0.68 10.4 5.2 0.77 10.2 5.2 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Laminin_I PF06008.14 EAX83785.1 - 5.1e-13 49.3 41.1 0.012 15.3 2.4 5.2 1 1 4 5 5 5 5 Laminin Domain I KASH_CCD PF14662.6 EAX83785.1 - 3.5e-11 43.3 42.6 0.00015 21.7 9.5 3.3 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX83785.1 - 2.9e-10 39.9 28.8 0.091 12.2 1.9 6.8 1 1 5 6 6 6 6 Domain of unknown function (DUF3552) ERM PF00769.19 EAX83785.1 - 7.1e-10 39.1 24.9 0.0079 16.0 6.4 4.5 1 1 3 4 4 4 4 Ezrin/radixin/moesin family Spc7 PF08317.11 EAX83785.1 - 2.2e-08 33.3 43.3 0.0032 16.4 9.6 4.4 1 1 4 5 5 5 5 Spc7 kinetochore protein BLOC1_2 PF10046.9 EAX83785.1 - 3.7e-05 24.0 34.6 1.3 9.3 1.6 7.3 1 1 4 5 5 5 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EAX83785.1 - 4.2e-05 23.6 28.0 0.46 10.5 1.3 5.1 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EAX83785.1 - 0.00013 22.3 2.0 16 5.9 0.0 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 EAX83785.1 - 0.00017 21.0 74.9 0.068 12.5 11.1 5.0 1 1 4 5 5 5 4 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 EAX83785.1 - 0.00024 21.2 19.0 46 4.3 0.1 8.9 2 1 6 10 10 10 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 EAX83785.1 - 0.00038 20.5 31.9 0.12 12.4 5.4 4.2 1 1 5 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EAX83785.1 - 0.00038 20.7 48.5 0.48 10.6 5.1 5.3 1 1 4 5 5 5 3 JNK_SAPK-associated protein-1 BRE1 PF08647.11 EAX83785.1 - 0.00046 20.2 37.8 0.75 9.9 4.7 5.2 1 1 6 7 7 7 6 BRE1 E3 ubiquitin ligase ZapB PF06005.12 EAX83785.1 - 0.00049 20.5 26.0 33 5.0 0.8 7.5 1 1 5 6 6 6 0 Cell division protein ZapB Laminin_II PF06009.12 EAX83785.1 - 0.00053 20.0 40.8 0.7 9.9 3.4 5.1 1 1 4 5 5 5 3 Laminin Domain II GCN5L1 PF06320.13 EAX83785.1 - 0.00056 20.0 21.3 6.3 7.0 0.2 6.7 1 1 6 7 7 7 0 GCN5-like protein 1 (GCN5L1) DUF4686 PF15742.5 EAX83785.1 - 0.00064 19.0 48.5 0.1 11.8 9.2 4.3 1 1 4 5 5 5 4 Domain of unknown function (DUF4686) YabA PF06156.13 EAX83785.1 - 0.00065 20.3 13.8 21 5.8 0.2 5.4 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EAX83785.1 - 0.0016 18.5 68.6 0.22 11.6 17.3 4.8 1 1 3 4 4 4 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EAX83785.1 - 0.0019 18.3 30.9 1.8 8.7 1.7 5.4 1 1 3 4 4 4 2 Tropomyosin like UPF0449 PF15136.6 EAX83785.1 - 0.0036 17.7 43.0 5 7.6 4.9 6.3 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 Fib_alpha PF08702.10 EAX83785.1 - 0.0094 16.1 33.2 0.51 10.5 2.9 4.6 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 EAX83785.1 - 0.0094 15.6 30.9 2.4 7.7 1.0 5.7 1 1 3 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ax_dynein_light PF10211.9 EAX83785.1 - 0.011 15.7 15.8 13 5.6 0.5 5.5 1 1 3 4 4 4 0 Axonemal dynein light chain DUF4201 PF13870.6 EAX83785.1 - 0.053 13.2 14.4 1.2 8.8 0.0 4.9 1 1 2 5 5 5 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 EAX83785.1 - 0.11 13.1 50.3 1.2 9.7 11.2 4.9 1 1 4 5 5 5 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 EAX83785.1 - 0.14 12.5 79.0 1.6e+04 -3.8 23.9 6.1 1 1 1 2 2 0 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sec34 PF04136.15 EAX83785.1 - 0.17 11.7 57.6 5.9 6.8 4.7 6.5 1 1 7 8 8 8 0 Sec34-like family PI_PP_I PF18363.1 EAX83785.1 - 0.19 11.9 14.3 28 5.0 0.3 5.7 1 1 6 7 7 7 0 Phosphoinositide phosphatase insertion domain Exonuc_VII_L PF02601.15 EAX83785.1 - 0.19 11.3 54.0 1.8e+04 -24.7 54.0 3.5 1 1 0 1 1 0 0 Exonuclease VII, large subunit DUF5082 PF16888.5 EAX83785.1 - 0.26 11.6 61.9 3 8.1 12.6 6.0 1 1 3 5 5 5 0 Domain of unknown function (DUF5082) DUF4795 PF16043.5 EAX83785.1 - 0.82 9.2 45.3 3.6e+02 0.6 15.8 5.5 1 1 1 2 2 1 0 Domain of unknown function (DUF4795) DUF724 PF05266.14 EAX83785.1 - 2.7 7.8 34.2 14 5.5 2.1 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF724) MAD PF05557.13 EAX83785.1 - 3.9 5.7 41.8 3.8 5.7 21.2 3.2 1 1 1 2 2 2 0 Mitotic checkpoint protein TMPIT PF07851.13 EAX83785.1 - 4.8 6.3 44.6 5.7 6.1 5.4 4.8 1 1 3 4 4 4 0 TMPIT-like protein Prominin PF05478.11 EAX83785.1 - 5.4 4.8 40.6 0.82 7.5 3.0 4.4 1 1 2 3 3 2 0 Prominin CheZ PF04344.13 EAX83785.1 - 6.4 6.6 33.0 46 3.8 5.7 4.5 1 1 3 4 4 4 0 Chemotaxis phosphatase, CheZ DUF563 PF04577.14 EAX83787.1 - 0.001 19.2 0.3 0.0017 18.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5365 PF17326.2 EAX83788.1 - 0.0084 16.5 0.2 0.019 15.4 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5365) PWI PF01480.17 EAX83788.1 - 0.031 14.6 0.3 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain KilA-N PF04383.13 EAX83789.1 - 1.7e-22 79.4 0.2 2.1e-22 79.1 0.2 1.1 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX83789.1 - 0.016 15.2 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pox_A32 PF04665.12 EAX83790.1 - 5.3e-08 32.6 0.9 6.4e-08 32.3 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83790.1 - 0.0053 16.4 0.1 0.0056 16.3 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX83790.1 - 0.062 13.3 0.4 0.58 10.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX83790.1 - 0.074 12.8 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T5orf172 PF10544.9 EAX83793.1 - 4.2e-07 30.5 0.3 8.5e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83794.1 - 3.2e-40 136.5 0.3 7.9e-40 135.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83794.1 - 0.013 16.1 0.2 0.032 14.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX83795.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83795.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83795.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83795.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83795.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83795.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83795.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83795.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX83795.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX83795.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83795.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83795.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83795.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX83797.1 - 7.5e-06 26.4 0.3 3.1e-05 24.5 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX83797.1 - 0.014 14.9 0.2 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83797.1 - 0.059 13.2 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX83798.1 - 1.1e-15 57.7 2.9 1.9e-15 57.0 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX83800.1 - 0.027 15.0 2.7 11 7.2 0.2 2.9 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX83801.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX83802.1 - 7.2e-158 523.3 13.6 9e-158 523.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83802.1 - 0.032 14.7 1.0 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX83802.1 - 0.17 11.7 1.5 0.38 10.6 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83802.1 - 0.46 11.0 6.3 2.5 8.6 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83802.1 - 0.9 10.1 5.5 0.42 11.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX83802.1 - 3.6 8.0 6.6 13 6.2 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAX83803.1 - 3.6e-45 152.4 0.3 9.5e-45 151.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Hormone_1 PF00103.20 EAX83803.1 - 0.37 10.5 5.3 3 7.5 2.0 2.2 1 1 1 2 2 2 0 Somatotropin hormone family Pox_A32 PF04665.12 EAX83804.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83804.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83804.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83804.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83804.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83804.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83804.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Myb_DNA-binding PF00249.31 EAX83805.1 - 4.8e-27 93.9 2.9 1.1e-15 57.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX83805.1 - 2.7e-22 78.8 0.5 6.6e-11 42.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX83805.1 - 1.6e-10 41.0 0.1 6e-06 26.3 0.0 2.4 1 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX83805.1 - 0.067 13.4 0.7 0.32 11.2 0.1 2.4 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 T5orf172 PF10544.9 EAX83806.1 - 0.0011 19.4 0.3 0.0023 18.4 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83806.1 - 0.094 12.2 0.3 0.19 11.2 0.1 1.5 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX83807.1 - 5.5e-155 513.9 14.3 6.4e-155 513.7 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83807.1 - 0.05 14.1 1.0 0.33 11.4 0.1 2.1 2 0 0 2 2 2 0 Fez1 THOC7 PF05615.13 EAX83807.1 - 0.094 13.0 0.2 0.094 13.0 0.2 1.9 2 1 0 2 2 2 0 Tho complex subunit 7 NTP_transf_6 PF06042.11 EAX83807.1 - 0.2 11.5 2.6 0.55 10.1 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83807.1 - 0.6 10.6 8.8 1.9 9.0 1.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMPIT PF07851.13 EAX83807.1 - 0.64 9.2 5.4 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein Rx_N PF18052.1 EAX83807.1 - 1.2 9.5 5.7 2.2 8.6 0.0 3.5 2 2 1 4 4 4 0 Rx N-terminal domain Tup_N PF08581.10 EAX83807.1 - 2.5 8.5 7.1 5.5 7.4 0.5 3.5 2 2 2 4 4 4 0 Tup N-terminal Med4 PF10018.9 EAX83807.1 - 2.8 7.6 5.5 10 5.8 1.2 2.3 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4108 PF13390.6 EAX83811.1 - 1.6e-53 180.5 5.4 1.7e-53 180.4 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX83812.1 - 1.3e-06 28.8 0.2 2.7e-06 27.9 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain TMP PF05017.14 EAX83815.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX83817.1 - 3.3e-05 23.9 0.6 3.3e-05 23.9 0.6 4.1 3 1 0 3 3 3 1 Phage tail repeat like DUF445 PF04286.12 EAX83817.1 - 0.0035 17.2 5.6 0.0053 16.6 5.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX83817.1 - 0.027 14.2 0.1 0.093 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX83817.1 - 0.063 13.0 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX83817.1 - 0.13 12.7 2.6 0.3 11.6 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) WD40 PF00400.32 EAX83819.1 - 5.5e-05 23.9 2.1 0.16 12.9 0.1 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX83819.1 - 0.00069 19.9 0.0 0.12 12.7 0.0 2.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EAX83819.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) LRR_5 PF13306.6 EAX83820.1 - 3.4e-16 59.4 0.1 9.8e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX83820.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat DUF5596 PF18082.1 EAX83820.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) DUF3839 PF12943.7 EAX83822.1 - 1e-153 509.8 11.8 1.3e-153 509.4 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83822.1 - 0.11 12.4 1.0 0.36 10.7 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX83822.1 - 1.8 8.9 4.1 8.7 6.7 0.0 3.3 2 2 2 4 4 4 0 Rx N-terminal domain DUF4292 PF14125.6 EAX83823.1 - 0.015 15.0 0.3 0.021 14.5 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4292) ABC_tran PF00005.27 EAX83824.1 - 1.3e-35 122.9 0.0 2.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAX83824.1 - 4.2e-17 62.7 8.6 5.9e-17 62.2 8.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EAX83824.1 - 3.7e-06 26.5 0.1 4.2e-05 23.1 0.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAX83824.1 - 3.8e-05 24.1 0.1 0.00022 21.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX83824.1 - 0.00035 20.5 0.0 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EAX83824.1 - 0.00077 19.3 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAX83824.1 - 0.0038 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAX83824.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 EAX83824.1 - 0.0059 16.9 0.1 0.053 13.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAX83824.1 - 0.011 15.8 0.0 0.27 11.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EAX83824.1 - 0.023 15.2 0.0 0.051 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83824.1 - 0.024 15.1 0.2 0.54 10.7 0.2 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAX83824.1 - 0.036 14.2 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX83824.1 - 0.039 13.5 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CMV_1a PF12467.8 EAX83824.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Rad17 PF03215.15 EAX83824.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EAX83824.1 - 0.084 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAX83824.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3839 PF12943.7 EAX83826.1 - 1e-156 519.5 13.9 1.3e-156 519.2 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83826.1 - 0.11 13.0 2.2 0.13 12.7 0.4 1.9 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX83826.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX83826.1 - 0.15 11.9 1.5 0.37 10.6 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83826.1 - 0.19 12.2 3.6 5.1 7.6 0.1 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX83827.1 - 1.3e-41 141.0 0.7 2.5e-41 140.0 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83827.1 - 0.015 15.9 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF4407 PF14362.6 EAX83828.1 - 0.047 13.0 22.4 0.84 8.9 18.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 EAX83828.1 - 0.41 11.1 22.3 0.8 10.2 0.2 4.2 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Ntox1 PF15500.6 EAX83828.1 - 0.6 10.5 5.7 0.97 9.8 1.0 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF1843 PF08898.10 EAX83828.1 - 1.2 9.7 4.1 26 5.4 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) EAP30 PF04157.16 EAX83828.1 - 2.8 7.1 13.3 0.25 10.6 6.4 2.5 1 1 0 2 2 2 0 EAP30/Vps36 family DUF4239 PF14023.6 EAX83828.1 - 4.8 6.8 8.1 0.98 9.1 3.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) Fez1 PF06818.15 EAX83828.1 - 6.8 7.1 29.8 3.4 8.1 20.3 2.2 1 1 1 2 2 2 0 Fez1 RPA_interact_C PF14768.6 EAX83828.1 - 9.1 6.9 7.0 15 6.3 0.1 2.9 2 1 1 3 3 3 0 Replication protein A interacting C-terminal Ank_4 PF13637.6 EAX83829.1 - 1.3e-14 54.4 0.3 1.3e-10 41.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX83829.1 - 1.8e-13 50.9 3.1 7.7e-10 39.2 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX83829.1 - 3.2e-13 49.4 5.7 3.2e-13 49.4 5.7 3.4 1 1 3 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX83829.1 - 2.6e-10 39.6 0.7 0.0025 18.2 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX83829.1 - 3.1e-08 33.7 0.1 1.3e-06 28.6 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX83829.1 - 9.6e-07 29.0 0.3 0.0012 19.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat DUF4535 PF15054.6 EAX83829.1 - 0.098 12.4 0.7 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) Ank_4 PF13637.6 EAX83830.1 - 7.8e-07 29.5 0.7 0.00013 22.4 0.1 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX83830.1 - 2.3e-06 28.1 0.7 6.5e-05 23.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX83830.1 - 9e-05 22.7 0.2 0.32 11.5 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX83830.1 - 0.00022 21.4 0.1 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83830.1 - 0.0019 18.5 0.1 15 6.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat CX PF01705.19 EAX83830.1 - 0.2 12.2 0.1 0.57 10.8 0.1 1.7 2 0 0 2 2 2 0 CX module DUF1340 PF07067.11 EAX83831.1 - 0.17 11.3 0.6 0.18 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) DUF682 PF05081.12 EAX83832.1 - 0.0049 16.6 5.5 0.005 16.6 1.8 2.6 1 1 1 3 3 3 1 Protein of unknown function (DUF682) DUF563 PF04577.14 EAX83833.1 - 8.1e-20 71.9 0.4 1.2e-19 71.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 EAX83834.1 - 7.9e-31 107.8 0.5 1.1e-30 107.3 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF563) GPS2_interact PF15784.5 EAX83836.1 - 0.06 13.8 2.3 0.082 13.4 2.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83836.1 - 0.076 12.0 0.1 0.077 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX83837.1 - 0.063 13.2 6.9 0.081 12.9 6.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX83838.1 - 7.8e-06 25.7 0.6 1.4e-05 24.9 0.0 1.7 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX83839.1 - 1.2e-157 522.6 13.1 1.4e-157 522.3 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83839.1 - 2.6 8.6 7.6 1.5 9.3 0.5 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83840.1 - 7.9e-06 26.4 0.1 2.2e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX83840.1 - 0.012 15.4 0.9 0.029 14.2 0.4 2.0 2 1 0 2 2 2 0 KilA-N domain Baculo_ME53 PF06061.11 EAX83840.1 - 0.014 14.7 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 MORN_2 PF07661.13 EAX83841.1 - 0.0004 20.3 0.1 1e+02 3.7 0.0 5.1 5 0 0 5 5 5 0 MORN repeat variant Autophagy_N PF03986.13 EAX83841.1 - 0.035 14.1 2.7 2.8 7.9 0.0 3.9 3 2 1 4 4 4 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF2689 PF10894.8 EAX83841.1 - 0.13 12.1 0.2 13 5.6 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2689) T5orf172 PF10544.9 EAX83842.1 - 9.7e-06 26.1 0.6 3.7e-05 24.2 0.2 2.1 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX83842.1 - 0.042 13.4 0.2 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83842.1 - 0.045 13.6 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX83843.1 - 7.4e-79 264.6 12.8 9.8e-79 264.2 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX83843.1 - 0.028 13.6 0.0 0.045 13.0 0.0 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EAX83843.1 - 0.037 14.5 0.3 0.044 14.2 0.3 1.2 1 0 0 1 1 1 0 Fez1 NTP_transf_6 PF06042.11 EAX83843.1 - 0.05 13.5 2.4 0.1 12.5 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX83844.1 - 1.2e-152 506.2 10.6 1.5e-152 505.9 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX83844.1 - 0.18 12.8 1.0 0.51 11.3 0.3 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pox_A32 PF04665.12 EAX83845.1 - 7.9e-08 32.0 0.9 9.6e-08 31.8 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83845.1 - 0.0042 16.7 0.1 0.0049 16.5 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX83845.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX83845.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83845.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) ResIII PF04851.15 EAX83846.1 - 2.2e-05 24.6 0.1 3.1e-05 24.0 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83846.1 - 0.0005 19.9 0.0 0.00068 19.5 0.0 1.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83846.1 - 0.0012 18.7 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX83846.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83846.1 - 0.0042 17.4 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX83846.1 - 0.023 14.1 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX83846.1 - 0.056 13.0 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX83846.1 - 0.069 12.9 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX83846.1 - 0.098 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 EAX83849.1 - 0.0033 17.4 6.7 0.0052 16.8 6.7 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) LRV PF01816.17 EAX83850.1 - 0.16 12.4 4.3 9.1 6.9 0.2 3.4 3 1 0 3 3 3 0 Leucine rich repeat variant DUF3724 PF12521.8 EAX83850.1 - 6.4 6.9 10.4 11 6.2 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) DUF3839 PF12943.7 EAX83851.1 - 2.1e-79 266.4 10.3 2.8e-79 266.0 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83851.1 - 0.082 12.8 1.1 0.32 10.8 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX83852.1 - 5e-72 241.4 3.4 6.5e-72 241.0 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX83853.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) PTR PF12789.7 EAX83854.1 - 4e-56 186.9 33.0 3.7e-34 116.6 15.2 5.3 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX83854.1 - 0.064 13.0 1.0 0.097 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PTR PF12789.7 EAX83856.1 - 3.4e-25 87.9 10.1 3.4e-25 87.9 10.1 4.3 4 1 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX83856.1 - 0.22 12.1 16.1 0.46 11.0 4.4 3.5 2 2 1 3 3 3 0 YmaF family DUF1493 PF07377.12 EAX83857.1 - 0.064 13.7 0.5 0.14 12.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Spo12 PF05032.12 EAX83858.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX83859.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83859.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83859.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83859.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83859.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83859.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83859.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83859.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83859.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83859.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83859.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83859.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX83860.1 - 3.1e-41 139.7 0.2 3.1e-41 139.7 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX83860.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX83860.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX83860.1 - 0.14 10.7 0.1 0.22 10.0 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) T5orf172 PF10544.9 EAX83861.1 - 1.1e-06 29.1 0.3 3.3e-06 27.6 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83861.1 - 0.057 12.9 0.6 0.71 9.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX83862.1 - 7.6e-49 166.3 2.1 9.1e-49 166.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX83863.1 - 5.3e-154 510.7 11.7 6.6e-154 510.4 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX83863.1 - 0.014 15.0 2.1 0.074 12.7 0.1 2.7 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit DUF2408 PF10303.9 EAX83863.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX83863.1 - 0.13 12.5 0.5 0.68 10.3 0.2 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX83863.1 - 0.6 10.6 3.7 4.8 7.7 0.1 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX83863.1 - 3.3 8.1 6.1 8.5 6.7 0.1 3.3 3 2 1 4 4 4 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX83864.1 - 3.2e-07 30.1 2.6 4.4e-07 29.6 2.6 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83864.1 - 0.0059 16.3 0.2 0.0075 15.9 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83864.1 - 0.04 13.4 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX83864.1 - 0.058 13.2 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) IstB_IS21 PF01695.17 EAX83864.1 - 0.058 13.1 0.2 0.48 10.1 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein APG12 PF04110.13 EAX83864.1 - 0.18 12.2 2.5 0.23 11.9 1.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF3783 PF12646.7 EAX83864.1 - 0.25 11.3 2.2 2.3 8.2 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) Gly-zipper_Omp PF13488.6 EAX83865.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX83865.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX83865.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Myb_DNA-binding PF00249.31 EAX83866.1 - 1.2e-31 108.6 0.5 1.8e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX83866.1 - 1.6e-22 79.5 2.1 1.4e-15 57.3 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX83866.1 - 2.5e-07 30.7 6.1 0.00051 20.0 0.1 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX83866.1 - 8.8e-05 22.3 5.9 0.0019 18.1 0.5 2.8 1 1 1 2 2 2 2 Myb DNA-binding like DUF4424 PF14415.6 EAX83866.1 - 0.00048 19.5 0.4 0.00049 19.5 0.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4424) SANT_DAMP1_like PF16282.5 EAX83866.1 - 0.0024 18.0 1.1 0.065 13.4 0.1 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX83866.1 - 0.003 17.7 0.8 1.6 9.0 0.3 3.0 1 1 1 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 EAX83866.1 - 0.0042 17.2 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF489 PF04356.12 EAX83866.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) RTP801_C PF07809.11 EAX83866.1 - 0.1 12.5 0.5 12 5.8 0.1 2.3 2 0 0 2 2 2 0 RTP801 C-terminal region DUF3839 PF12943.7 EAX83867.1 - 5.2e-157 520.5 14.2 6.6e-157 520.2 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX83867.1 - 0.1 13.0 0.4 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX83867.1 - 0.13 12.1 1.5 0.5 10.2 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83867.1 - 0.42 11.1 5.0 5.1 7.6 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX83868.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX83870.1 - 2.2e-05 24.6 0.2 2.7e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83870.1 - 0.00026 20.8 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX83870.1 - 0.00096 19.4 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX83870.1 - 0.0018 18.1 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX83870.1 - 0.0062 16.9 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX83870.1 - 0.028 13.9 0.0 0.058 12.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX83870.1 - 0.052 13.3 0.0 0.072 12.8 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX83870.1 - 0.079 12.5 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX83870.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX83871.1 - 1.2e-07 31.5 1.2 1.4e-07 31.2 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83871.1 - 0.004 16.8 0.1 0.0044 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX83871.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83871.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) GPS2_interact PF15784.5 EAX83874.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83874.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX83876.1 - 1.3e-148 493.0 11.8 1.8e-148 492.5 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX83876.1 - 0.0022 18.5 0.5 0.074 13.6 0.2 3.0 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX83876.1 - 0.015 15.7 1.2 0.041 14.3 0.2 1.9 2 0 0 2 2 2 0 Fez1 Lectin_legB PF00139.19 EAX83876.1 - 0.1 12.1 1.4 0.28 10.7 0.4 1.9 2 0 0 2 2 2 0 Legume lectin domain KELK PF15796.5 EAX83876.1 - 0.4 11.2 4.7 2.8 8.4 0.8 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX83877.1 - 8.3e-06 26.3 0.2 2.1e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX83877.1 - 0.017 14.6 0.8 1.5 8.3 0.2 2.1 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX83877.1 - 0.058 13.3 0.2 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX83878.1 - 3.4e-149 494.9 11.6 4.2e-149 494.6 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX83878.1 - 0.14 12.7 2.1 0.29 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX83878.1 - 6.3 7.3 7.9 6.1 7.4 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2897 PF11446.8 EAX83879.1 - 1.9 8.4 4.1 3.7 7.5 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX83880.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83880.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83880.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83880.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83880.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83880.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83880.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83880.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX83880.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83880.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX83880.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83880.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX83881.1 - 4.9e-44 148.7 0.3 1.1e-43 147.6 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83881.1 - 0.018 15.7 0.1 0.059 14.0 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX83881.1 - 0.4 10.7 2.8 7.9 6.5 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF3839 PF12943.7 EAX83882.1 - 5.8e-39 134.0 4.3 7.8e-39 133.6 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX83882.1 - 0.074 13.4 0.8 0.29 11.5 0.1 2.1 1 1 1 2 2 2 0 PRD domain Pkinase_Tyr PF07714.17 EAX83883.1 - 2.8e-28 98.9 0.0 4.8e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX83883.1 - 1.3e-23 83.7 0.0 2.6e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EAX83883.1 - 0.0016 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAX83883.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX83883.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family eIF-5a PF01287.20 EAX83884.1 - 1.3e-20 73.3 0.3 2.3e-20 72.4 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EAX83884.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Peptidase_C14 PF00656.22 EAX83884.1 - 0.06 13.3 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Caspase domain DUF3839 PF12943.7 EAX83885.1 - 6e-153 507.2 13.3 7.6e-153 506.9 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX83885.1 - 0.059 13.6 0.9 0.19 12.0 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF29 KELK PF15796.5 EAX83885.1 - 1.5 9.4 6.0 1.8 9.1 0.4 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APC_u14 PF16635.5 EAX83885.1 - 1.5 9.4 4.5 1.5 9.4 2.3 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Ras PF00071.22 EAX83888.1 - 4e-53 179.3 0.6 5e-53 179.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX83888.1 - 2.3e-31 108.5 0.8 3.8e-31 107.8 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX83888.1 - 4.3e-15 55.6 0.1 5.2e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX83888.1 - 7.4e-08 32.0 0.1 9.4e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX83888.1 - 8.7e-06 25.3 0.1 1.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX83888.1 - 0.00013 21.6 0.3 0.00044 19.8 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX83888.1 - 0.0002 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MnmE_helical PF12631.7 EAX83888.1 - 0.0099 16.1 0.1 0.01 16.0 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain AAA_22 PF13401.6 EAX83888.1 - 0.13 12.5 0.5 23 5.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain HMD PF03201.16 EAX83889.1 - 0.089 13.0 2.0 0.16 12.2 2.0 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF3671 PF12420.8 EAX83889.1 - 4.5 7.4 18.9 1.4 9.1 9.2 2.6 2 1 0 2 2 2 0 Protein of unknown function KilA-N PF04383.13 EAX83890.1 - 1.7e-15 56.8 0.1 2.3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain RPAP3_C PF13877.6 EAX83890.1 - 0.068 13.7 0.1 0.09 13.3 0.1 1.1 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 YbfN PF13982.6 EAX83890.1 - 0.073 13.4 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 YbfN-like lipoprotein KilA-N PF04383.13 EAX83891.1 - 5.2e-43 145.4 0.3 1.3e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83891.1 - 0.0051 17.4 0.1 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX83892.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83892.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX83892.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX83892.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX83892.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX83892.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX83892.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_D5 PF03288.16 EAX83894.1 - 8.3e-05 23.0 2.4 0.00055 20.4 2.4 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like VHL PF01847.16 EAX83895.1 - 0.00057 19.7 0.1 0.89 9.5 0.0 2.2 1 1 1 2 2 2 2 VHL beta domain Cas9_C PF18525.1 EAX83895.1 - 0.018 15.2 0.5 0.19 12.0 0.1 2.2 1 1 1 2 2 2 0 Cas9 C-terminal domain CmcI PF04989.12 EAX83895.1 - 0.17 11.5 0.1 7.5 6.2 0.0 2.1 1 1 1 2 2 2 0 Cephalosporin hydroxylase Collagen_bind_2 PF12904.7 EAX83896.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Trypan_PARP PF05887.11 EAX83898.1 - 0.045 13.7 10.2 0.06 13.3 10.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX83899.1 - 1.8e-65 220.0 13.2 8.8e-64 214.5 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX83900.1 - 0.0039 16.8 0.1 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase CTU2 PF10288.9 EAX83902.1 - 0.067 13.4 0.2 0.22 11.8 0.0 1.7 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4061 PF13270.6 EAX83902.1 - 0.087 13.2 2.6 0.1 12.9 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) zf-DNA_Pol PF08996.10 EAX83902.1 - 0.16 11.7 0.4 0.18 11.6 0.4 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger SlyX PF04102.12 EAX83902.1 - 0.26 11.9 2.6 3.7 8.2 0.6 2.2 1 1 1 2 2 2 0 SlyX DPM3 PF08285.11 EAX83903.1 - 0.25 11.6 0.9 2.1 8.6 0.2 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sulfatase PF00884.23 EAX83904.1 - 4e-16 59.3 0.3 5.4e-16 58.9 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Thioredoxin PF00085.20 EAX83905.1 - 7.3e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ABC_transp_aux PF09822.9 EAX83905.1 - 0.0092 15.5 0.3 0.014 14.9 0.3 1.4 1 1 0 1 1 1 1 ABC-type uncharacterized transport system Glutaredoxin PF00462.24 EAX83905.1 - 0.013 15.7 0.1 0.083 13.1 0.0 2.4 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.6 EAX83905.1 - 0.013 15.8 0.0 0.097 13.0 0.0 2.1 1 1 2 3 3 3 0 Thioredoxin-like Orn_DAP_Arg_deC PF00278.22 EAX83906.1 - 1.3e-10 41.4 0.0 1.6e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3447 PF11929.8 EAX83908.1 - 8.5e-41 137.8 6.6 8.5e-41 137.8 6.6 3.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX83908.1 - 6.5e-24 84.3 8.2 1.6e-13 51.0 0.9 3.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX83908.1 - 3.3e-19 69.0 5.4 8.6e-07 29.4 0.1 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX83908.1 - 2.9e-18 65.4 3.2 5.2e-06 26.7 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX83908.1 - 1.4e-15 55.8 8.8 0.00012 22.2 0.0 6.8 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX83908.1 - 1.1e-09 38.4 2.9 6.2e-08 32.8 0.2 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) RAMPs PF03787.15 EAX83908.1 - 0.091 12.8 2.5 0.17 11.9 2.5 1.4 1 0 0 1 1 1 0 RAMP superfamily DUF3839 PF12943.7 EAX83909.1 - 1.2e-154 512.8 12.5 1.5e-154 512.5 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83909.1 - 0.27 11.7 4.1 5.1 7.6 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83909.1 - 0.41 11.2 4.9 1 9.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX83911.1 - 5.6e-158 523.7 13.9 6.9e-158 523.4 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX83911.1 - 3 8.4 8.1 1.5 9.3 0.5 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase IBD PF10416.9 EAX83912.1 - 4.8e-31 107.4 0.6 5.7e-31 107.2 0.6 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD T5orf172 PF10544.9 EAX83913.1 - 7e-06 26.5 0.5 2.1e-05 25.0 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain DUF3839 PF12943.7 EAX83914.1 - 3.1e-154 511.4 13.6 3.8e-154 511.1 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83914.1 - 0.09 12.6 1.0 0.3 10.9 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase FKBP_N PF01346.18 EAX83914.1 - 0.52 11.3 3.5 0.29 12.1 0.3 2.1 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4108 PF13390.6 EAX83915.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX83916.1 - 3.2 7.7 4.6 6.7 6.7 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX83917.1 - 0.048 13.9 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EAX83917.1 - 0.077 13.0 0.1 0.11 12.5 0.1 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX83917.1 - 0.083 12.3 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DUF4107 PF13389.6 EAX83918.1 - 3.2e-59 199.7 2.2 3.8e-59 199.5 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX83918.1 - 0.067 11.6 1.0 0.093 11.1 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF4106 PF13388.6 EAX83920.1 - 2.1e-66 224.9 2.0 2.4e-66 224.7 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX83921.1 - 6.5e-08 32.3 1.1 7.8e-08 32.1 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX83921.1 - 0.0044 16.7 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX83921.1 - 0.05 13.3 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX83921.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3653 PF12375.8 EAX83922.1 - 0.037 14.1 2.2 21 5.3 0.1 3.3 3 1 0 3 3 3 0 Phage protein MORN_2 PF07661.13 EAX83922.1 - 0.041 14.1 0.0 31 5.2 0.0 3.4 4 0 0 4 4 4 0 MORN repeat variant DUF2689 PF10894.8 EAX83922.1 - 0.16 11.7 1.1 1.6 8.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2689) SHIPPO-rpt PF07004.12 EAX83922.1 - 4.6 8.3 12.3 6.1 7.9 0.4 3.7 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat KilA-N PF04383.13 EAX83923.1 - 5.6e-43 145.4 1.8 5.7e-43 145.3 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX83923.1 - 0.012 16.2 0.5 0.037 14.6 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX83924.1 - 1.1e-06 29.1 0.2 2.1e-06 28.2 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX83925.1 - 5.7e-07 29.2 2.5 5.7e-07 29.2 2.5 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83925.1 - 2.7e-05 24.0 0.3 0.33 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83925.1 - 8.2e-05 22.9 0.2 0.00053 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83925.1 - 0.00014 21.9 3.2 0.00025 21.1 2.7 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83925.1 - 0.00057 19.7 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83925.1 - 0.0021 17.9 0.5 0.0043 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83925.1 - 0.0024 17.5 0.5 0.013 15.1 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83925.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX83925.1 - 0.061 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX83925.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX83925.1 - 0.088 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX83925.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83925.1 - 0.13 12.7 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 EAX83929.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAX83929.1 - 0.088 12.1 0.0 0.088 12.1 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3858 PF12970.7 EAX83930.1 - 0.13 12.3 2.2 0.28 11.2 0.2 2.7 2 2 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3858) Pkinase PF00069.25 EAX83931.1 - 2e-71 240.5 0.0 2.4e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX83931.1 - 1.1e-33 116.6 0.0 1.1e-32 113.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX83931.1 - 0.0069 16.3 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX83931.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DUF1387 PF07139.11 EAX83931.1 - 0.028 14.1 0.9 0.028 14.1 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PDEase_I PF00233.19 EAX83932.1 - 7.5e-55 186.2 1.2 1.2e-54 185.6 1.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Syntaxin_2 PF14523.6 EAX83932.1 - 0.057 13.8 1.1 0.63 10.4 0.2 2.8 3 0 0 3 3 3 0 Syntaxin-like protein DUF4108 PF13390.6 EAX83933.1 - 4.7e-68 227.6 9.5 5.6e-68 227.3 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pkinase_C PF00433.24 EAX83935.1 - 2.2e-06 28.2 0.1 3.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF3839 PF12943.7 EAX83936.1 - 1.1e-156 519.4 13.8 1.4e-156 519.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83936.1 - 0.17 11.8 1.3 0.55 10.1 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX83936.1 - 0.79 10.2 7.6 1.3 9.5 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RibD_C PF01872.17 EAX83937.1 - 4.6e-13 49.5 0.0 5.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF4478 PF14793.6 EAX83937.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases RibD_C PF01872.17 EAX83938.1 - 3.1e-13 50.0 0.0 3.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF4478 PF14793.6 EAX83938.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases LRR_5 PF13306.6 EAX83939.1 - 4.2e-85 282.2 56.9 6.1e-23 81.2 12.0 5.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX83939.1 - 9.1e-16 57.4 0.0 0.21 11.4 0.0 7.6 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EAX83939.1 - 7.4e-05 23.0 0.9 7 7.2 0.0 6.7 5 2 3 8 8 8 1 Leucine Rich repeats (2 copies) HNHc_6 PF16784.5 EAX83939.1 - 0.086 12.4 0.4 15 5.1 0.0 2.9 3 0 0 3 3 3 0 Putative HNHc nuclease EF-hand_10 PF14788.6 EAX83940.1 - 0.11 12.4 1.0 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 EF hand DUF4108 PF13390.6 EAX83941.1 - 0.0052 16.7 8.0 0.0065 16.4 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phi-29_GP4 PF05464.11 EAX83941.1 - 0.087 13.1 1.3 0.15 12.3 0.3 1.9 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) DUF3447 PF11929.8 EAX83942.1 - 6.4e-10 38.8 7.2 2.1e-08 34.0 1.2 3.1 2 2 2 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX83942.1 - 0.0048 17.5 0.1 7 7.4 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX83942.1 - 0.0088 16.4 0.0 33 4.9 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX83942.1 - 0.017 15.6 0.4 4.4 8.2 0.0 4.1 3 1 1 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 EAX83942.1 - 0.022 15.3 0.0 3.9 8.1 0.0 2.6 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Peptidase_S8 PF00082.22 EAX83943.1 - 0.0086 15.4 0.3 0.019 14.2 0.3 1.4 1 1 0 1 1 1 1 Subtilase family KilA-N PF04383.13 EAX83944.1 - 5e-43 145.5 0.4 1.1e-42 144.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX83945.1 - 1.2e-06 28.2 1.9 1.2e-06 28.2 1.9 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83945.1 - 3.1e-05 23.8 0.4 0.3 10.8 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83945.1 - 4.7e-05 23.7 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83945.1 - 0.00045 20.3 4.9 0.0006 19.9 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83945.1 - 0.00073 19.4 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83945.1 - 0.003 17.4 1.4 0.0069 16.2 0.7 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83945.1 - 0.0053 16.4 2.6 0.018 14.7 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83945.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX83945.1 - 0.083 13.0 0.6 1.2 9.2 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX83945.1 - 0.091 12.3 0.0 0.3 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX83945.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83945.1 - 0.11 12.9 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX83945.1 - 0.33 11.2 4.8 4.3 7.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2805 PF10985.8 EAX83945.1 - 0.86 10.0 0.0 0.86 10.0 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2805) DUF573 PF04504.14 EAX83945.1 - 2.3 9.0 11.7 0.43 11.3 1.7 3.5 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Imm70 PF15601.6 EAX83946.1 - 0.059 12.9 3.4 0.9 9.1 0.1 2.6 1 1 3 4 4 4 0 Immunity protein 70 DUF3447 PF11929.8 EAX83946.1 - 1.4 8.9 16.9 38 4.3 3.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DDR PF08841.10 EAX83947.1 - 0.092 11.7 0.2 0.094 11.7 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Collagen_bind_2 PF12904.7 EAX83949.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Trypan_PARP PF05887.11 EAX83950.1 - 0.81 9.7 8.6 0.95 9.4 8.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX83952.1 - 6.4e-32 109.7 0.2 1.6e-31 108.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX83953.1 - 1e-05 26.0 0.4 3.7e-05 24.2 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX83953.1 - 0.0031 17.1 0.1 0.2 11.2 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain DUF3839 PF12943.7 EAX83954.1 - 7.3e-157 520.0 12.2 9.1e-157 519.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX83954.1 - 0.063 13.6 0.4 2.1 8.7 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX83954.1 - 0.44 11.0 5.0 4.8 7.7 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX83954.1 - 2 8.8 6.6 12 6.3 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal GGDEF PF00990.21 EAX83955.1 - 0.039 13.7 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX83955.1 - 1.4 8.9 3.8 2.8 7.9 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX83956.1 - 2.8e-57 192.7 4.8 3.1e-57 192.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ACP_PD PF04336.12 EAX83957.1 - 0.058 13.8 0.1 0.31 11.5 0.0 2.1 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase GPS2_interact PF15784.5 EAX83960.1 - 0.054 13.9 1.5 0.076 13.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX83960.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain EVC2_like PF12297.8 EAX83961.1 - 0.0018 17.0 0.1 0.0027 16.5 0.1 1.2 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein Trypan_PARP PF05887.11 EAX83961.1 - 0.14 12.1 8.3 0.23 11.5 8.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX83962.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX83963.1 - 0.011 16.1 0.6 0.014 15.8 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX83963.1 - 2.7 8.0 5.8 2.9 7.9 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PadR PF03551.14 EAX83964.1 - 0.039 13.9 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF1043 PF06295.12 EAX83964.1 - 0.043 13.8 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX83965.1 - 2.2e-28 99.4 11.6 1.1e-27 97.1 11.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Trypan_PARP PF05887.11 EAX83966.1 - 0.031 14.3 8.1 0.048 13.7 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX83966.1 - 1.2 9.6 5.3 1.7 9.1 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX83967.1 - 0.14 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain CHRD PF07452.12 EAX83969.1 - 0.12 13.3 2.6 1.3 10.0 2.6 2.1 1 1 0 1 1 1 0 CHRD domain DUF4107 PF13389.6 EAX83971.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83971.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Pox_A32 PF04665.12 EAX83974.1 - 5.5e-07 29.3 1.9 5.5e-07 29.3 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX83974.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX83974.1 - 5.2e-05 23.5 0.2 0.00041 20.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX83974.1 - 8e-05 22.7 2.2 0.0002 21.4 2.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83974.1 - 0.00055 19.7 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83974.1 - 0.0017 18.2 0.5 0.0032 17.3 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83974.1 - 0.0021 17.7 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83974.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX83974.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX83974.1 - 0.075 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX83974.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX83974.1 - 0.09 13.2 0.0 0.73 10.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX83974.1 - 0.093 12.5 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1827 PF08860.10 EAX83974.1 - 0.42 10.9 4.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX83975.1 - 3.5e-32 110.6 0.6 6.9e-32 109.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX83976.1 - 4.4e-07 30.4 0.1 1.1e-06 29.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain DUF4107 PF13389.6 EAX83978.1 - 2e-72 242.6 4.6 2.4e-72 242.4 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83978.1 - 0.082 13.3 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX83979.1 - 2.5e-78 262.9 10.5 3.1e-78 262.6 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX83979.1 - 0.2 11.5 1.6 0.86 9.5 1.6 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase PRD PF00874.20 EAX83979.1 - 0.22 11.8 1.8 0.94 9.8 0.1 2.5 3 0 0 3 3 3 0 PRD domain TPR_MLP1_2 PF07926.12 EAX83980.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX83980.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX83980.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DDE_1 PF03184.19 EAX83981.1 - 1.6e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EAX83982.1 - 4e-13 49.4 0.0 7.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Mo-nitro_C PF06967.11 EAX83985.1 - 9.7 6.2 18.3 3.5 7.6 1.7 3.3 1 1 2 3 3 3 0 Mo-dependent nitrogenase C-terminus DUF5623 PF18536.1 EAX83987.1 - 0.075 13.3 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX83987.1 - 0.82 9.6 6.0 0.46 10.4 1.3 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX83989.1 - 2.4e-06 27.2 2.0 2.4e-06 27.2 2.0 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX83989.1 - 2.6e-05 24.5 0.2 0.0002 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX83989.1 - 3.7e-05 23.5 0.3 0.29 10.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX83989.1 - 0.00014 21.9 3.3 0.00031 20.8 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX83989.1 - 0.00053 19.8 0.1 0.00099 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX83989.1 - 0.0011 18.8 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX83989.1 - 0.0011 18.6 0.4 0.0079 15.9 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX83989.1 - 0.0099 16.2 0.0 0.02 15.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX83989.1 - 0.059 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX83989.1 - 0.07 13.6 0.1 0.61 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX83989.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX83989.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX83989.1 - 0.41 10.9 4.3 9.2 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Amidase02_C PF12123.8 EAX83990.1 - 0.0041 16.8 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX83991.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX83993.1 - 0.0016 18.5 1.7 0.0019 18.2 1.7 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Helicase_PWI PF18149.1 EAX83993.1 - 0.029 14.6 0.8 0.046 13.9 0.5 1.5 1 1 0 1 1 1 0 N-terminal helicase PWI domain PaRep2a PF07903.11 EAX83993.1 - 0.033 14.0 0.2 0.042 13.7 0.2 1.2 1 0 0 1 1 1 0 PaRep2a protein BspA_v PF18220.1 EAX83994.1 - 1.3 9.1 6.8 4.2 7.5 1.2 2.3 2 1 0 2 2 2 0 Adhesin BspA variable domain DUF4107 PF13389.6 EAX83995.1 - 5e-66 221.8 13.2 1.4e-64 217.1 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX83995.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX83996.1 - 1.3e-157 522.5 13.5 1.6e-157 522.2 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX83996.1 - 0.027 14.9 1.7 0.061 13.8 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX83996.1 - 0.62 10.6 7.3 1.5 9.3 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX83996.1 - 1.8 9.2 5.1 0.64 10.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX83996.1 - 2.3 8.6 6.1 12 6.3 0.1 3.7 4 2 2 6 6 6 0 Tup N-terminal T5orf172 PF10544.9 EAX83999.1 - 6.9e-07 29.8 0.3 1.3e-06 28.9 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX83999.1 - 0.12 13.1 0.2 0.21 12.3 0.2 1.5 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX84000.1 - 5.1e-43 145.5 0.7 1.2e-42 144.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84000.1 - 0.019 15.5 1.0 0.071 13.7 0.0 2.3 3 0 0 3 3 3 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX84001.1 - 3.8e-07 29.8 2.1 5.7e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84001.1 - 0.0045 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX84001.1 - 0.056 12.9 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX84001.1 - 0.062 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX84001.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2805 PF10985.8 EAX84001.1 - 0.19 12.1 3.6 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF3783 PF12646.7 EAX84001.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX84001.1 - 0.59 10.4 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX84002.1 - 2.3e-140 466.0 10.6 2.8e-140 465.7 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX84002.1 - 0.28 11.7 2.5 4.4 7.8 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX84002.1 - 0.31 11.5 5.6 4.3 7.9 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84002.1 - 0.56 10.8 3.5 0.73 10.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) LAP1C PF05609.12 EAX84003.1 - 0.003 16.7 9.9 0.0043 16.2 9.9 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) TMEM190 PF15431.6 EAX84003.1 - 0.13 12.4 0.3 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 190 DUF4711 PF15829.5 EAX84003.1 - 0.16 11.9 4.5 0.07 13.1 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4711) Orf78 PF06024.12 EAX84003.1 - 2.3 8.6 7.1 88 3.5 7.1 3.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF2370 PF10176.9 EAX84003.1 - 5.7 6.5 10.5 93 2.5 10.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2370) DUF3781 PF12636.7 EAX84004.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX84005.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84005.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX84006.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84006.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RFX_DNA_binding PF02257.15 EAX84007.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX84007.1 - 0.00065 20.1 1.5 0.001 19.5 1.5 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX84007.1 - 0.043 13.8 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain UDG PF03167.19 EAX84009.1 - 1.2e-22 80.6 0.1 2.2e-22 79.7 0.0 1.4 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DegS PF05384.11 EAX84010.1 - 0.074 12.5 0.1 0.079 12.4 0.1 1.1 1 0 0 1 1 1 0 Sensor protein DegS T2SSB PF16537.5 EAX84010.1 - 0.22 11.2 0.4 6.5 6.4 0.1 2.7 2 1 1 3 3 3 0 Type II secretion system protein B Spo12 PF05032.12 EAX84011.1 - 0.8 9.7 8.0 0.18 11.7 2.9 2.3 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX84012.1 - 3.7e-152 504.6 12.7 4.7e-152 504.3 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84012.1 - 0.063 13.7 1.4 3.3 8.2 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX84012.1 - 0.14 12.6 0.4 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX84012.1 - 0.29 11.7 4.1 0.34 11.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX84012.1 - 0.37 11.1 3.5 17 5.8 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX84013.1 - 2.6e-42 143.2 1.0 6.2e-42 142.0 0.1 2.1 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84013.1 - 0.023 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX84015.1 - 1.1e-121 404.8 12.4 1.4e-121 404.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84015.1 - 0.019 15.4 1.1 0.69 10.4 0.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX84015.1 - 0.096 12.5 1.0 0.28 11.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX84016.1 - 0.008 16.0 0.4 0.018 14.9 0.4 1.7 1 1 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX84016.1 - 0.015 15.8 0.2 0.032 14.8 0.2 1.5 1 0 0 1 1 1 0 T5orf172 domain Baculo_ME53 PF06061.11 EAX84016.1 - 0.048 12.9 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX84016.1 - 0.072 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Legume lectin domain DUF3839 PF12943.7 EAX84017.1 - 2.6e-155 515.0 13.9 3.3e-155 514.6 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84017.1 - 2.4 8.7 6.3 2 9.0 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX84018.1 - 0.083 13.4 0.7 0.22 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX84019.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3781 PF12636.7 EAX84021.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX84022.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX84022.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX84023.1 - 0.045 13.7 8.4 0.067 13.2 8.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Collagen_bind_2 PF12904.7 EAX84024.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAX84025.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX84027.1 - 7.5e-143 474.1 9.2 9.3e-143 473.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84027.1 - 0.076 13.4 0.2 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84027.1 - 1.3 9.5 4.7 9.1 6.8 0.2 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84028.1 - 5.6e-07 30.0 0.1 1.4e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84028.1 - 0.0068 16.2 0.2 0.045 13.6 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain RNA_bind PF08675.11 EAX84028.1 - 0.073 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain KilA-N PF04383.13 EAX84029.1 - 3.4e-33 113.8 0.9 8.1e-33 112.6 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain IstB_IS21 PF01695.17 EAX84030.1 - 2.2e-05 24.3 0.4 0.27 11.0 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84030.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX84030.1 - 6.5e-05 22.5 2.1 6.5e-05 22.5 2.1 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX84030.1 - 0.0004 20.4 4.9 0.00067 19.7 4.3 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84030.1 - 0.00055 19.8 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84030.1 - 0.0026 17.6 1.5 0.0059 16.4 0.8 1.9 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84030.1 - 0.0043 16.7 2.5 0.014 15.1 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84030.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84030.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84030.1 - 0.075 13.5 0.1 0.73 10.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84030.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX84030.1 - 0.11 12.5 0.6 1.5 8.9 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX84030.1 - 0.49 10.7 4.7 8.2 6.8 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX84030.1 - 3.9 8.2 11.5 0.29 11.8 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAX84031.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HMG_box PF00505.19 EAX84032.1 - 3.6e-09 36.9 0.2 5.8e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX84032.1 - 4.3e-09 36.8 0.4 1.1e-08 35.6 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 EAX84032.1 - 0.0002 21.3 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF3106 PF11304.8 EAX84032.1 - 0.06 13.8 0.6 0.12 12.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) YABBY PF04690.13 EAX84032.1 - 0.062 13.9 0.1 0.097 13.2 0.0 1.4 1 1 0 1 1 1 0 YABBY protein Myb_DNA-binding PF00249.31 EAX84033.1 - 4.8e-20 71.5 0.0 9.3e-09 35.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX84033.1 - 3.1e-17 62.5 0.1 5.6e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX84033.1 - 4.7e-06 26.6 0.1 0.015 15.3 0.1 3.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX84033.1 - 0.0017 18.2 1.5 0.07 13.0 0.1 2.4 2 1 0 2 2 2 1 Myb DNA-binding like NHS PF15273.6 EAX84033.1 - 0.091 11.9 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 NHS-like T5orf172 PF10544.9 EAX84034.1 - 1.1e-06 29.2 0.3 1.9e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84035.1 - 3.6e-40 136.3 0.8 6.4e-40 135.5 0.3 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84035.1 - 0.0068 17.0 0.1 0.02 15.5 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family RsfS PF02410.15 EAX84035.1 - 0.013 15.9 0.3 0.027 14.9 0.3 1.6 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation Acyl_transf_2 PF02273.15 EAX84035.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX84035.1 - 0.26 9.8 0.1 0.38 9.3 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4108 PF13390.6 EAX84036.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX84039.1 - 6.2e-07 29.9 0.1 1.5e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX84040.1 - 7.8e-157 519.9 13.3 9.9e-157 519.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84040.1 - 0.093 12.6 1.2 0.25 11.2 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX84040.1 - 0.11 13.0 0.4 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84040.1 - 1.1 9.8 4.9 6.6 7.3 0.2 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Metallophos PF00149.28 EAX84041.1 - 2.8e-16 60.7 1.0 2.8e-16 60.7 1.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase UNC-50 PF05216.13 EAX84041.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 UNC-50 family DUF3839 PF12943.7 EAX84042.1 - 5.1e-05 22.8 1.4 8.2e-05 22.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX84043.1 - 1.2e-06 28.9 0.5 4.7e-06 27.1 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX84043.1 - 0.037 13.6 0.6 0.42 10.1 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX84043.1 - 0.25 11.2 1.8 0.85 9.5 0.5 2.4 2 2 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX84044.1 - 1.5e-33 114.9 0.8 2.7e-33 114.2 0.0 1.8 2 1 1 3 3 3 1 KilA-N domain Pox_A32 PF04665.12 EAX84045.1 - 5e-07 29.4 2.1 5e-07 29.4 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84045.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84045.1 - 5.1e-05 23.6 0.2 0.0004 20.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84045.1 - 8.9e-05 22.5 2.4 0.00021 21.3 2.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84045.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84045.1 - 0.0014 18.5 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84045.1 - 0.002 17.8 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84045.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84045.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84045.1 - 0.088 13.2 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84045.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84045.1 - 0.32 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX84046.1 - 2.1e-45 152.6 27.3 5.8e-32 109.5 13.0 4.3 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX84046.1 - 0.04 13.7 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX84047.1 - 2.3e-154 511.9 15.2 2.9e-154 511.5 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84047.1 - 0.016 15.5 0.8 0.36 11.1 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX84047.1 - 0.16 11.8 1.9 0.38 10.6 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84047.1 - 0.28 11.7 7.3 2.4 8.7 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX84047.1 - 3 8.2 7.5 9.3 6.6 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal DUF1947 PF09183.10 EAX84048.1 - 0.021 15.1 1.8 0.074 13.4 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) EpuA PF11772.8 EAX84048.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TPR_MLP1_2 PF07926.12 EAX84049.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX84049.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX84049.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX84049.1 - 6.2 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family PapD_N PF00345.20 EAX84050.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX84050.1 - 0.086 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EF-hand_10 PF14788.6 EAX84052.1 - 0.0015 18.3 0.8 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 EF hand DUF2855 PF11017.8 EAX84052.1 - 0.04 13.7 0.6 0.045 13.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) LPD30 PF18850.1 EAX84052.1 - 0.084 12.6 2.3 0.31 10.8 0.8 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 YmgB PF10798.8 EAX84053.1 - 0.0081 16.0 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR Amidase02_C PF12123.8 EAX84056.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX84057.1 - 7.9e-13 48.9 0.5 8.8e-13 48.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX84058.1 - 1.5e-33 116.2 3.3 1.8e-33 116.0 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX84058.1 - 0.12 10.8 1.0 0.12 10.8 1.0 1.0 1 0 0 1 1 1 0 Lipoxygenase DUF5365 PF17326.2 EAX84060.1 - 0.012 16.0 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4107 PF13389.6 EAX84062.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84062.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DRMBL PF07522.14 EAX84063.1 - 8.2e-24 83.9 0.1 1.3e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EAX84063.1 - 7.7e-07 28.8 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAX84063.1 - 0.012 15.7 1.5 0.12 12.4 1.5 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EAX84063.1 - 0.015 15.2 0.1 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Pox_polyA_pol PF03296.13 EAX84063.1 - 0.099 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain E3_UbLigase_EDD PF11547.8 EAX84064.1 - 0.019 14.6 1.1 0.06 13.0 1.1 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD DUF3839 PF12943.7 EAX84066.1 - 8e-82 274.3 3.3 9.8e-82 274.0 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX84066.1 - 0.12 13.0 0.9 0.25 12.0 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Pox_A32 PF04665.12 EAX84067.1 - 1.7e-07 31.0 0.5 2.1e-07 30.7 0.5 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX84067.1 - 0.0051 15.7 0.0 0.0067 15.3 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF3783 PF12646.7 EAX84067.1 - 0.052 13.5 0.4 0.47 10.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX84067.1 - 0.062 13.0 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.12 EAX84067.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3839 PF12943.7 EAX84068.1 - 4.6e-157 520.7 15.7 5.8e-157 520.4 15.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84068.1 - 0.099 13.1 2.2 0.16 12.4 0.4 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX84068.1 - 0.14 11.7 0.6 0.41 10.1 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 KELK PF15796.5 EAX84068.1 - 0.89 10.1 7.5 2.4 8.7 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ANAPC1 PF12859.7 EAX84072.1 - 0.092 13.3 2.5 0.11 13.1 2.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 CcmF_C PF16327.5 EAX84072.1 - 0.15 11.4 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Pox_A32 PF04665.12 EAX84073.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84073.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX84073.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX84073.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX84073.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX84073.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX84073.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX84074.1 - 1.3e-79 267.1 9.2 1.6e-79 266.8 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX84075.1 - 1.8e-86 284.2 58.0 4e-34 116.5 16.9 6.1 5 2 2 7 7 7 3 Phage tail repeat like DUF4116 PF13475.6 EAX84075.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX84075.1 - 0.29 10.9 4.4 0.88 9.3 2.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2785) DUF3839 PF12943.7 EAX84076.1 - 8.4e-157 519.8 13.4 1.1e-156 519.5 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84076.1 - 0.032 14.5 1.7 0.045 14.0 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX84076.1 - 0.26 11.8 5.8 2.5 8.6 0.8 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84076.1 - 0.66 10.5 5.6 0.41 11.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX84077.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84077.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX84077.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX84077.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84077.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX84077.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF4106 PF13388.6 EAX84078.1 - 3.4e-277 919.3 22.8 4.9e-277 918.8 22.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX84078.1 - 0.00085 19.6 0.1 0.039 14.3 0.2 2.5 2 0 0 2 2 2 1 Kidney androgen-regulated DDE_1 PF03184.19 EAX84079.1 - 2.3e-15 56.7 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_5 PF13306.6 EAX84085.1 - 7e-09 35.7 5.0 1.3e-08 34.8 5.0 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) PapD_N PF00345.20 EAX84087.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX84087.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX84088.1 - 0.084 13.3 0.6 0.1 13.0 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX84088.1 - 2.1 7.3 4.5 2.2 7.2 4.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein LRR_5 PF13306.6 EAX84090.1 - 4.5e-135 443.7 118.5 5.6e-27 94.2 18.1 7.2 2 1 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84090.1 - 8.4e-26 89.5 11.4 0.032 14.0 0.2 12.9 8 4 7 15 15 15 8 Leucine rich repeat LRR_4 PF12799.7 EAX84090.1 - 5.1e-06 26.7 16.4 20 5.7 0.0 9.9 6 3 3 9 9 9 4 Leucine Rich repeats (2 copies) DUF3839 PF12943.7 EAX84091.1 - 1.8e-158 525.3 13.2 2.2e-158 525.0 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84091.1 - 2 8.9 7.9 1.5 9.4 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84092.1 - 1.6e-06 28.6 0.1 3.6e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84092.1 - 0.011 15.6 1.7 0.061 13.2 0.8 2.5 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX84092.1 - 0.041 13.4 0.5 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX84093.1 - 1.1e-41 141.2 0.2 1.1e-41 141.2 0.2 2.0 2 1 1 3 3 3 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX84093.1 - 0.035 13.3 0.2 0.15 11.3 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase FAM76 PF16046.5 EAX84093.1 - 0.63 9.3 4.2 0.98 8.7 4.2 1.3 1 0 0 1 1 1 0 FAM76 protein DUF3839 PF12943.7 EAX84094.1 - 2e-155 515.3 8.8 2.5e-155 515.0 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84094.1 - 0.06 13.8 1.8 5.2 7.6 0.1 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84094.1 - 0.94 10.0 5.3 0.36 11.4 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX84094.1 - 1.7 9.0 5.8 16 5.9 0.1 3.7 4 1 1 5 5 5 0 Tup N-terminal Aldo_ket_red PF00248.21 EAX84095.1 - 1.4e-46 159.0 0.1 5.8e-46 157.0 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EAX84095.1 - 0.016 15.1 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Development and cell death domain LRR_5 PF13306.6 EAX84096.1 - 2.3e-100 331.5 89.6 1.3e-27 96.2 0.1 5.8 2 2 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84096.1 - 2.7e-21 75.1 0.4 0.017 14.8 0.2 8.6 6 2 5 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 EAX84096.1 - 9.6e-06 25.9 20.3 1.8 9.1 0.0 7.8 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) DUF2179 PF10035.9 EAX84096.1 - 0.061 13.1 0.0 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Crystall_2 PF09076.10 EAX84096.1 - 0.28 11.1 4.6 5.3 7.0 0.0 3.8 4 0 0 4 4 4 0 Beta/Gamma crystallin DUF4107 PF13389.6 EAX84097.1 - 1.1e-44 152.5 0.5 1.2e-44 152.3 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX84098.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX84099.1 - 2e-156 518.6 13.7 2.5e-156 518.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84099.1 - 0.069 13.0 0.8 0.29 11.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84099.1 - 0.073 13.4 0.4 1.4 9.2 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX84099.1 - 0.13 12.7 0.4 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84099.1 - 1.5 9.4 7.6 2.1 8.9 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5446 PF17522.2 EAX84100.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Gly_rich PF12810.7 EAX84102.1 - 4.6e-08 33.3 14.3 5.4e-08 33.0 14.3 1.1 1 0 0 1 1 1 1 Glycine rich protein TFIIF_beta_N PF17683.1 EAX84103.1 - 0.094 13.4 2.4 0.13 13.0 2.4 1.2 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus TMEM43 PF07787.12 EAX84103.1 - 0.32 10.4 3.7 0.35 10.2 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 CDC45 PF02724.14 EAX84103.1 - 2.2 6.4 8.6 2.5 6.3 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 EAX84103.1 - 8.3 5.4 14.5 9.3 5.3 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_A32 PF04665.12 EAX84104.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84104.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84104.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84104.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84104.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84104.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84104.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84104.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84104.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84104.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84104.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84104.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84105.1 - 1.1e-14 54.2 1.0 2.3e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain SLC35F PF06027.12 EAX84106.1 - 2.5e-30 106.1 22.5 3.1e-30 105.7 22.5 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX84106.1 - 4.8e-13 49.5 36.6 4.6e-08 33.3 14.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAX84106.1 - 7.1e-05 22.1 20.2 0.00027 20.3 20.2 1.7 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EAX84106.1 - 0.0011 18.3 6.4 0.0011 18.3 6.4 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport PKcGMP_CC PF16808.5 EAX84108.1 - 1.3e-28 98.5 36.5 0.00018 21.3 0.2 10.3 3 2 8 11 11 10 7 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EAX84108.1 - 1.2e-13 51.5 37.8 0.013 15.8 0.4 7.0 1 1 5 6 6 6 5 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 EAX84108.1 - 2.4e-13 49.9 63.3 0.00087 19.2 3.3 6.8 2 2 3 6 6 6 4 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EAX84108.1 - 9.9e-13 47.6 43.2 1.8e-05 23.8 5.4 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein Csm1_N PF18504.1 EAX84108.1 - 1.2e-12 48.0 49.2 0.045 14.1 0.3 8.8 1 1 9 10 10 10 6 Csm1 N-terminal domain Fez1 PF06818.15 EAX84108.1 - 1.9e-12 48.1 41.3 1.6e-06 28.7 5.6 4.5 1 1 4 5 5 5 4 Fez1 Fib_alpha PF08702.10 EAX84108.1 - 4e-12 46.5 47.2 2.5e-06 27.8 8.9 4.9 2 1 3 5 5 4 4 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 EAX84108.1 - 1.7e-11 44.2 59.3 4.6e-06 26.3 21.6 3.7 1 1 3 4 4 4 4 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 EAX84108.1 - 3.8e-11 43.2 33.5 0.00037 20.2 13.9 3.3 1 1 2 3 3 3 3 Intermediate filament protein Bap31_Bap29_C PF18035.1 EAX84108.1 - 2e-10 40.5 48.8 0.00091 19.2 2.3 9.3 5 3 5 10 10 9 2 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_13 PF13166.6 EAX84108.1 - 6.3e-10 38.4 36.0 8e-09 34.7 24.2 2.1 1 1 1 2 2 2 2 AAA domain Lebercilin PF15619.6 EAX84108.1 - 6.5e-10 39.0 44.3 1.4e-07 31.3 13.8 3.7 1 1 3 4 4 4 3 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 EAX84108.1 - 2.7e-09 35.8 45.7 1.7e-05 23.3 12.7 2.9 1 1 2 3 3 3 3 HOOK protein CEP63 PF17045.5 EAX84108.1 - 1.1e-08 35.3 37.0 0.016 15.2 1.4 5.9 1 1 4 6 6 6 4 Centrosomal protein of 63 kDa HAP1_N PF04849.13 EAX84108.1 - 1.3e-08 34.5 36.4 5.7e-05 22.5 4.2 4.4 1 1 3 4 4 4 3 HAP1 N-terminal conserved region Atg14 PF10186.9 EAX84108.1 - 3.9e-08 32.7 56.9 3.5e-05 23.1 12.2 3.4 1 1 2 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EAX84108.1 - 5.2e-08 33.3 42.7 0.00011 22.5 9.4 3.4 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 EAX84108.1 - 6.4e-08 32.9 43.7 0.0045 17.2 7.0 5.9 1 1 6 7 7 7 3 Tropomyosin like TPD52 PF04201.15 EAX84108.1 - 8e-08 32.1 26.5 0.091 12.4 2.4 6.1 1 1 5 6 6 6 4 Tumour protein D52 family Golgin_A5 PF09787.9 EAX84108.1 - 3.2e-07 30.1 44.8 0.019 14.4 22.6 3.4 1 1 2 3 3 3 3 Golgin subfamily A member 5 BRE1 PF08647.11 EAX84108.1 - 5.5e-07 29.6 45.4 0.0019 18.2 1.4 4.5 1 1 3 4 4 4 3 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 EAX84108.1 - 6e-07 29.4 44.1 0.00059 19.6 2.4 4.7 1 1 3 4 4 4 3 Domain of unknown function (DUF4201) MAD PF05557.13 EAX84108.1 - 6.9e-07 28.0 40.2 6e-06 24.9 26.6 2.5 1 1 1 2 2 2 2 Mitotic checkpoint protein SPATA24 PF15175.6 EAX84108.1 - 7e-07 29.3 50.9 0.047 13.6 2.2 5.4 1 1 3 4 4 4 3 Spermatogenesis-associated protein 24 HrpB7 PF09486.10 EAX84108.1 - 7.5e-07 29.7 8.0 0.47 10.8 0.0 4.8 1 1 5 6 6 6 1 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 EAX84108.1 - 1.2e-06 29.0 43.0 0.086 13.5 2.0 5.5 1 1 5 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3552 PF12072.8 EAX84108.1 - 1.7e-06 27.6 43.2 0.0027 17.1 4.3 4.2 1 1 4 5 5 5 3 Domain of unknown function (DUF3552) UPF0242 PF06785.11 EAX84108.1 - 1.9e-06 28.1 46.9 0.00011 22.4 10.0 3.5 1 1 3 4 4 4 3 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 EAX84108.1 - 2.1e-06 27.9 25.5 0.04 14.2 0.3 6.8 2 2 6 8 8 8 1 ABC transporter C-terminal domain SlyX PF04102.12 EAX84108.1 - 2.5e-06 28.0 26.4 0.34 11.6 0.1 6.3 1 1 6 8 8 8 2 SlyX Cluap1 PF10234.9 EAX84108.1 - 2.7e-06 27.0 39.9 0.00026 20.5 13.1 3.9 1 1 2 4 4 4 3 Clusterin-associated protein-1 Cast PF10174.9 EAX84108.1 - 3.8e-06 25.5 45.2 5.6e-06 24.9 41.8 2.1 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone TolA_bind_tri PF16331.5 EAX84108.1 - 4.2e-06 26.8 37.2 0.016 15.3 0.3 6.2 3 2 3 6 6 5 2 TolA binding protein trimerisation Phage_GPO PF05929.11 EAX84108.1 - 4.6e-06 26.5 27.3 0.01 15.5 9.3 4.3 1 1 3 4 4 4 1 Phage capsid scaffolding protein (GPO) serine peptidase ERM PF00769.19 EAX84108.1 - 7.8e-06 25.9 24.4 0.025 14.4 11.6 2.8 1 1 2 3 3 3 3 Ezrin/radixin/moesin family GrpE PF01025.19 EAX84108.1 - 1e-05 25.2 32.3 0.097 12.3 0.2 5.6 1 1 5 6 6 6 5 GrpE DUF5082 PF16888.5 EAX84108.1 - 1.1e-05 25.8 50.4 0.00036 20.8 16.8 5.0 1 1 3 4 4 4 3 Domain of unknown function (DUF5082) Laminin_I PF06008.14 EAX84108.1 - 1.2e-05 25.1 30.1 0.00045 20.0 4.5 3.8 1 1 2 3 3 3 1 Laminin Domain I TPR_MLP1_2 PF07926.12 EAX84108.1 - 1.4e-05 25.1 43.3 0.16 12.0 3.3 4.6 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 EAX84108.1 - 1.5e-05 23.1 35.4 0.00054 17.9 14.8 2.3 1 1 1 2 2 2 2 Myosin tail CENP-F_leu_zip PF10473.9 EAX84108.1 - 1.6e-05 25.0 47.6 0.55 10.2 6.9 4.8 1 1 4 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 EAX84108.1 - 3e-05 23.1 43.5 0.0017 17.4 14.7 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF812) DUF4407 PF14362.6 EAX84108.1 - 3.2e-05 23.4 24.8 28 3.9 24.9 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 EAX84108.1 - 4.9e-05 22.8 43.0 0.03 13.7 5.8 4.6 1 1 3 4 4 4 2 FAM76 protein ADIP PF11559.8 EAX84108.1 - 5.7e-05 23.2 46.9 0.018 15.1 5.7 4.7 1 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 EAX84108.1 - 8.9e-05 22.5 32.8 0.2 11.7 0.6 5.4 1 1 5 6 6 6 2 Designed helical repeat protein 10 domain Spc29 PF17082.5 EAX84108.1 - 0.00011 22.1 39.1 0.022 14.6 7.9 4.4 1 1 3 4 4 4 2 Spindle Pole Component 29 MscS_porin PF12795.7 EAX84108.1 - 0.00014 21.6 47.3 0.066 12.7 14.7 3.1 1 1 2 3 3 3 3 Mechanosensitive ion channel porin domain GAS PF13851.6 EAX84108.1 - 0.00018 20.9 40.1 0.17 11.2 15.4 3.7 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding XLF PF09302.11 EAX84108.1 - 0.00029 21.1 42.0 0.086 13.0 1.2 6.4 1 1 7 8 8 8 3 XLF-Cernunnos, XRcc4-like factor, NHEJ component Leu_zip PF15294.6 EAX84108.1 - 0.0003 20.4 38.5 0.0046 16.5 13.6 3.1 1 1 2 3 3 3 3 Leucine zipper FPP PF05911.11 EAX84108.1 - 0.0003 19.1 45.0 0.058 11.6 13.9 2.7 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 EAX84108.1 - 0.00037 20.4 40.6 0.0054 16.6 8.1 3.7 1 1 3 4 4 4 3 Protein of unknown function (DUF724) DUF4763 PF15960.5 EAX84108.1 - 0.0004 19.8 40.3 0.013 14.8 1.9 4.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4763) WEMBL PF05701.11 EAX84108.1 - 0.00045 19.1 34.2 0.0047 15.7 15.0 2.2 1 1 1 2 2 2 2 Weak chloroplast movement under blue light DUF1664 PF07889.12 EAX84108.1 - 0.0005 20.1 30.6 0.074 13.1 7.4 4.4 1 1 4 5 5 5 3 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 EAX84108.1 - 0.00056 19.4 3.9 0.00056 19.4 3.9 4.4 1 1 2 4 4 4 1 Tropomyosin TMPIT PF07851.13 EAX84108.1 - 0.0006 19.2 37.8 0.086 12.1 4.5 3.3 1 1 2 3 3 3 3 TMPIT-like protein Tup_N PF08581.10 EAX84108.1 - 0.00068 19.9 26.9 0.0017 18.6 0.3 5.7 2 1 4 6 6 6 1 Tup N-terminal TMF_TATA_bd PF12325.8 EAX84108.1 - 0.00071 19.8 40.5 0.44 10.8 2.8 6.6 1 1 5 6 6 6 2 TATA element modulatory factor 1 TATA binding MPS2 PF17060.5 EAX84108.1 - 0.00082 18.7 23.2 0.00082 18.7 23.2 3.1 1 1 2 3 3 3 1 Monopolar spindle protein 2 APG6_N PF17675.1 EAX84108.1 - 0.00093 19.7 43.2 0.34 11.4 6.1 3.9 1 1 2 3 3 3 1 Apg6 coiled-coil region E2R135 PF11570.8 EAX84108.1 - 0.0015 18.8 19.4 0.83 9.9 0.3 5.9 1 1 5 6 6 6 1 Coiled-coil receptor-binding R-domain of colicin E2 Phe_tRNA-synt_N PF02912.18 EAX84108.1 - 0.0019 18.1 6.2 1.3 9.0 0.1 5.4 3 2 3 6 6 4 0 Aminoacyl tRNA synthetase class II, N-terminal domain TACC_C PF05010.14 EAX84108.1 - 0.0019 18.0 38.4 0.28 10.9 8.6 3.7 1 1 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4349 PF14257.6 EAX84108.1 - 0.0019 17.7 32.9 0.016 14.7 8.1 4.7 1 1 3 4 4 4 1 Domain of unknown function (DUF4349) HemX PF04375.14 EAX84108.1 - 0.0022 17.4 35.3 0.21 10.8 1.2 4.2 1 1 1 2 2 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase CALCOCO1 PF07888.11 EAX84108.1 - 0.0026 16.7 40.8 0.015 14.2 12.8 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 EAX84108.1 - 0.0026 18.1 40.6 0.64 10.4 8.3 5.8 2 2 2 4 4 3 1 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 EAX84108.1 - 0.003 17.6 35.6 0.0058 16.7 0.4 7.6 4 3 3 7 7 6 1 bZIP transcription factor BLOC1_2 PF10046.9 EAX84108.1 - 0.0036 17.6 36.5 0.031 14.6 9.0 5.6 1 1 4 6 6 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CC2-LZ PF16516.5 EAX84108.1 - 0.0037 17.6 38.5 2 8.8 0.3 7.0 1 1 4 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF16 PF01519.16 EAX84108.1 - 0.0039 17.7 34.9 0.54 10.8 3.8 4.6 1 1 3 4 4 4 2 Protein of unknown function DUF16 FlaC_arch PF05377.11 EAX84108.1 - 0.0047 17.3 36.6 0.21 12.0 1.0 7.5 1 1 6 7 7 7 1 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EAX84108.1 - 0.0055 16.6 46.5 0.16 11.9 1.2 6.8 1 1 5 8 8 7 2 Prefoldin subunit DUF211 PF02680.14 EAX84108.1 - 0.0063 16.7 3.3 0.32 11.2 0.2 3.6 3 1 3 6 6 5 1 Uncharacterized ArCR, COG1888 Med4 PF10018.9 EAX84108.1 - 0.0085 15.8 38.8 1.9 8.1 5.5 5.5 1 1 3 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1192 PF06698.11 EAX84108.1 - 0.01 15.9 10.2 1 9.5 0.0 5.5 4 3 1 5 5 4 0 Protein of unknown function (DUF1192) Exonuc_VII_L PF02601.15 EAX84108.1 - 0.01 15.4 38.3 1.8e+04 -5.8 38.3 2.9 1 1 0 1 1 0 0 Exonuclease VII, large subunit DUF2730 PF10805.8 EAX84108.1 - 0.018 15.2 21.8 0.8 9.8 0.8 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF2730) Swi5 PF07061.11 EAX84108.1 - 0.018 15.1 39.3 1.3 9.2 0.3 7.4 2 2 2 4 4 2 0 Swi5 NYD-SP28 PF14772.6 EAX84108.1 - 0.019 15.0 37.5 6.1 7.0 0.2 6.8 3 2 3 6 6 6 0 Sperm tail Gp58 PF07902.11 EAX84108.1 - 0.019 13.3 36.2 0.16 10.3 13.2 2.2 1 1 1 2 2 2 0 gp58-like protein DUF4094 PF13334.6 EAX84108.1 - 0.022 15.2 42.7 4.3 7.8 2.5 6.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) Mod_r PF07200.13 EAX84108.1 - 0.035 14.2 48.2 0.34 11.0 12.9 4.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 EAX84108.1 - 0.036 14.1 38.1 0.26 11.4 2.7 5.6 1 1 4 5 5 5 0 Centrosome localisation domain of PPC89 DUF4088 PF13317.6 EAX84108.1 - 0.043 13.4 5.4 2.3 7.7 0.7 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF4088) KASH_CCD PF14662.6 EAX84108.1 - 0.044 13.6 40.7 0.098 12.5 8.9 3.6 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 EAX84108.1 - 0.058 13.2 0.5 0.058 13.2 0.5 7.5 2 2 6 8 8 7 0 Septum formation initiator Cob_adeno_trans PF01923.18 EAX84108.1 - 0.063 13.4 12.6 4.5 7.4 4.5 4.0 1 1 2 3 3 3 0 Cobalamin adenosyltransferase DUF4472 PF14739.6 EAX84108.1 - 0.073 13.8 33.3 0.24 12.2 1.9 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4472) ZapB PF06005.12 EAX84108.1 - 0.081 13.4 0.3 0.081 13.4 0.3 5.4 1 1 2 3 3 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 EAX84108.1 - 0.082 13.2 39.0 0.21 11.9 12.7 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Cut12 PF11500.8 EAX84108.1 - 0.083 12.8 28.2 1.6 8.7 0.5 6.0 1 1 4 5 5 5 0 Spindle pole body formation-associated protein Spectrin PF00435.21 EAX84108.1 - 0.083 13.4 24.4 1.9 9.0 8.2 4.7 1 1 4 5 5 5 0 Spectrin repeat DUF3584 PF12128.8 EAX84108.1 - 0.083 10.4 38.7 0.7 7.3 16.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) PKHD_C PF18331.1 EAX84108.1 - 0.091 12.8 8.7 16 5.7 0.0 6.3 4 3 4 9 9 5 0 PKHD-type hydroxylase C-terminal domain LRRFIP PF09738.9 EAX84108.1 - 0.1 12.0 41.7 0.14 11.6 4.8 4.3 1 1 0 2 2 2 0 LRRFIP family Med9 PF07544.13 EAX84108.1 - 0.12 12.5 40.8 1.1 9.4 12.2 5.4 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 COG5 PF10392.9 EAX84108.1 - 0.12 12.6 41.0 0.043 14.0 4.1 5.0 1 1 4 5 5 5 0 Golgi transport complex subunit 5 HAUS-augmin3 PF14932.6 EAX84108.1 - 0.13 11.9 36.3 1.6 8.3 1.7 3.4 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 Fungal_TACC PF12709.7 EAX84108.1 - 0.13 12.7 37.9 1.7 9.2 1.6 6.6 1 1 3 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins EzrA PF06160.12 EAX84108.1 - 0.19 9.9 39.2 0.22 9.7 19.0 2.8 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.11 EAX84108.1 - 0.2 11.5 38.8 7.7 6.3 6.1 5.1 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CCDC-167 PF15188.6 EAX84108.1 - 0.24 11.7 40.6 0.11 12.9 5.3 5.6 1 1 2 3 3 2 0 Coiled-coil domain-containing protein 167 WD40_alt PF14077.6 EAX84108.1 - 0.29 11.0 6.0 45 4.0 0.0 5.4 5 1 1 7 7 3 0 Alternative WD40 repeat motif DUF948 PF06103.11 EAX84108.1 - 0.29 11.4 6.2 13 6.1 2.6 3.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 EAX84108.1 - 0.31 11.7 28.4 2.2 9.0 3.9 5.3 1 1 2 3 3 2 0 Initiation control protein YabA Occludin_ELL PF07303.13 EAX84108.1 - 0.34 11.7 30.2 0.094 13.4 10.6 4.5 1 1 3 4 4 4 0 Occludin homology domain Nup54 PF13874.6 EAX84108.1 - 0.43 10.7 26.0 1.5 8.9 10.5 3.5 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 DUF2203 PF09969.9 EAX84108.1 - 0.45 11.2 21.5 33 5.2 1.0 4.4 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 EAX84108.1 - 0.45 9.1 39.6 0.17 10.4 14.1 3.3 1 1 2 3 3 3 0 Flagellar Assembly Protein A RPW8 PF05659.11 EAX84108.1 - 0.46 10.2 30.7 0.52 10.0 3.4 6.2 2 2 5 7 7 7 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Jnk-SapK_ap_N PF09744.9 EAX84108.1 - 0.48 10.6 38.9 0.31 11.3 5.5 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 SYCE1 PF15233.6 EAX84108.1 - 0.49 10.4 32.8 0.12 12.5 1.7 3.7 1 1 3 4 4 3 0 Synaptonemal complex central element protein 1 IFT57 PF10498.9 EAX84108.1 - 0.56 9.1 39.6 1.3 8.0 12.1 3.2 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DASH_Spc34 PF08657.10 EAX84108.1 - 0.58 9.9 43.7 0.34 10.7 5.0 3.6 1 1 2 3 3 3 0 DASH complex subunit Spc34 PI3K_P85_iSH2 PF16454.5 EAX84108.1 - 0.71 9.5 41.3 0.46 10.1 17.8 4.3 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Phage_tail_NK PF16532.5 EAX84108.1 - 0.86 9.2 30.3 0.36 10.4 2.2 5.2 2 1 3 5 5 5 0 Sf6-type phage tail needle knob or tip of some Caudovirales Spc24 PF08286.11 EAX84108.1 - 0.88 9.8 41.2 61 3.9 7.0 6.2 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 EAX84108.1 - 0.99 9.9 29.2 17 5.9 1.2 6.1 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) L31 PF09784.9 EAX84108.1 - 1.1 9.7 23.0 4.7 7.7 0.8 5.2 1 1 3 4 4 4 0 Mitochondrial ribosomal protein L31 DUF4795 PF16043.5 EAX84108.1 - 1.5 8.4 39.1 4 7.0 0.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Val_tRNA-synt_C PF10458.9 EAX84108.1 - 2 8.7 23.0 13 6.1 0.7 6.6 3 2 3 7 7 7 0 Valyl tRNA synthetase tRNA binding arm PCRF PF03462.18 EAX84108.1 - 2.4 8.0 30.1 1.6 8.6 5.0 3.8 1 1 2 3 3 2 0 PCRF domain MIP-T3_C PF17749.1 EAX84108.1 - 2.5 8.0 33.0 6.7 6.7 6.8 5.3 1 1 2 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region NPV_P10 PF05531.12 EAX84108.1 - 2.5 8.6 29.4 3.1 8.3 2.9 5.8 1 1 3 4 4 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 EAX84108.1 - 2.8 7.6 20.3 2.2 8.0 0.5 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 EAX84108.1 - 2.9 7.1 39.6 1.6 8.0 7.2 4.6 1 1 3 5 5 5 0 Protein of unknown function (DUF3450) Rho_Binding PF08912.11 EAX84108.1 - 3.1 8.7 39.6 20 6.1 1.7 6.4 1 1 5 6 6 6 0 Rho Binding APG17 PF04108.12 EAX84108.1 - 3.3 6.7 35.4 0.86 8.6 3.4 2.7 1 1 1 2 2 2 0 Autophagy protein Apg17 USP8_interact PF08941.10 EAX84108.1 - 4.2 7.1 26.7 8.9 6.1 1.5 5.1 1 1 3 4 4 4 0 USP8 interacting Laminin_II PF06009.12 EAX84108.1 - 4.6 7.3 33.3 0.52 10.3 9.6 3.8 1 1 3 4 4 4 0 Laminin Domain II DUF3138 PF11336.8 EAX84108.1 - 4.6 5.7 7.2 6.1 5.3 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) SHE3 PF17078.5 EAX84108.1 - 5.3 6.7 51.1 0.2 11.3 17.4 3.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Yuri_gagarin PF15934.5 EAX84108.1 - 5.5 6.8 37.3 6 6.6 2.7 3.8 1 1 2 3 3 3 0 Yuri gagarin DUF4988 PF16378.5 EAX84108.1 - 6.5 6.4 21.3 3.2 7.4 0.0 5.8 3 2 3 6 6 6 0 Domain of unknown function Spc42p PF11544.8 EAX84108.1 - 8 6.5 35.4 36 4.5 0.1 7.9 4 1 5 9 9 8 0 Spindle pole body component Spc42p RasGAP_C PF03836.15 EAX84108.1 - 8.7 6.5 38.8 0.41 10.8 2.9 4.8 1 1 3 4 4 3 0 RasGAP C-terminus Ank_4 PF13637.6 EAX84109.1 - 3.7e-09 37.0 0.1 1.8e-05 25.2 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX84109.1 - 8.6e-09 35.9 1.4 1.6e-06 28.6 0.2 3.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Spc7 PF08317.11 EAX84109.1 - 1.1e-05 24.5 21.2 2.3e-05 23.4 21.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF641 PF04859.12 EAX84109.1 - 6.5e-05 23.3 22.2 0.005 17.2 12.8 2.7 1 1 1 2 2 2 2 Plant protein of unknown function (DUF641) Filament PF00038.21 EAX84109.1 - 7.2e-05 22.5 16.4 0.00015 21.5 16.4 1.6 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.8 EAX84109.1 - 0.00016 21.6 43.2 0.011 15.7 8.5 3.9 3 1 1 4 4 3 3 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 EAX84109.1 - 0.0003 19.6 18.9 0.00046 19.0 18.9 1.2 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.6 EAX84109.1 - 0.00037 20.0 8.8 0.00069 19.1 8.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Bap31_Bap29_C PF18035.1 EAX84109.1 - 0.0022 18.0 3.2 0.0022 18.0 3.2 4.5 2 2 2 4 4 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain HMMR_N PF15905.5 EAX84109.1 - 0.0026 17.3 32.1 0.2 11.1 9.9 2.5 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 EAX84109.1 - 0.003 17.8 21.9 0.003 17.8 21.9 1.5 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) Ank_5 PF13857.6 EAX84109.1 - 0.0043 17.3 0.5 0.1 12.9 0.0 3.2 4 0 0 4 4 2 1 Ankyrin repeats (many copies) MAD PF05557.13 EAX84109.1 - 0.0043 15.5 26.8 0.024 13.0 13.8 1.9 1 1 1 2 2 2 2 Mitotic checkpoint protein BLOC1_2 PF10046.9 EAX84109.1 - 0.005 17.1 21.9 0.085 13.2 11.1 2.7 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 EAX84109.1 - 0.0055 16.5 4.5 0.027 14.3 1.1 4.5 3 1 3 6 6 5 3 Coiled-coil N-terminus of cGMP-dependent protein kinase Exonuc_VII_L PF02601.15 EAX84109.1 - 0.0059 16.2 12.1 0.011 15.4 12.1 1.5 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4349 PF14257.6 EAX84109.1 - 0.011 15.2 5.7 0.011 15.2 5.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Gp58 PF07902.11 EAX84109.1 - 0.011 14.1 13.4 0.017 13.5 13.4 1.2 1 0 0 1 1 1 0 gp58-like protein HAP1_N PF04849.13 EAX84109.1 - 0.012 14.8 21.0 0.022 14.0 21.0 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region V_ATPase_I PF01496.19 EAX84109.1 - 0.013 13.5 11.4 0.023 12.7 11.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EAX84109.1 - 0.013 14.6 21.3 0.027 13.6 21.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EAX84109.1 - 0.016 15.4 25.8 0.029 14.5 16.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EAX84109.1 - 0.018 15.1 5.3 0.047 13.7 5.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EAX84109.1 - 0.019 15.2 4.7 0.13 12.6 0.1 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 EAX84109.1 - 0.019 15.0 21.9 0.019 15.0 21.9 2.9 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase DUF2385 PF09539.10 EAX84109.1 - 0.03 14.8 0.7 0.13 12.8 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Sec34 PF04136.15 EAX84109.1 - 0.031 14.1 24.2 0.031 14.2 10.3 2.4 1 1 1 2 2 2 0 Sec34-like family DUF3584 PF12128.8 EAX84109.1 - 0.045 11.3 21.0 0.065 10.8 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 EAX84109.1 - 0.059 12.7 29.7 0.054 12.9 17.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EAX84109.1 - 0.12 12.1 22.0 0.23 11.2 2.8 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 EAX84109.1 - 0.12 12.8 13.8 1.2 9.7 3.3 3.2 1 1 2 3 3 2 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 EAX84109.1 - 0.15 11.7 17.6 0.26 10.8 4.0 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF812 PF05667.11 EAX84109.1 - 0.16 10.9 28.3 0.35 9.7 15.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3552 PF12072.8 EAX84109.1 - 0.18 11.2 26.1 0.13 11.7 16.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.15 EAX84109.1 - 0.19 12.2 26.4 0.16 12.4 23.3 2.3 2 1 1 3 3 2 0 Fez1 ZnuA PF01297.17 EAX84109.1 - 0.21 11.0 7.9 0.49 9.8 7.6 1.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic HOOK PF05622.12 EAX84109.1 - 0.3 9.2 27.4 1.2 7.2 27.5 1.7 1 1 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 EAX84109.1 - 0.3 11.1 13.2 0.83 9.7 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TACC_C PF05010.14 EAX84109.1 - 0.33 10.7 26.7 0.15 11.9 5.0 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Phage_GPO PF05929.11 EAX84109.1 - 0.35 10.4 19.1 0.13 11.9 9.8 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Lipoprotein_6 PF01441.19 EAX84109.1 - 0.38 10.7 13.2 3.4 7.6 1.5 2.8 1 1 1 2 2 2 0 Lipoprotein PI3K_P85_iSH2 PF16454.5 EAX84109.1 - 0.38 10.3 28.1 0.87 9.2 27.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Csm1_N PF18504.1 EAX84109.1 - 0.39 11.1 28.1 0.18 12.2 2.8 4.1 1 1 3 4 4 4 0 Csm1 N-terminal domain HrpB7 PF09486.10 EAX84109.1 - 0.39 11.1 5.0 1.5 9.2 5.0 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 EAX84109.1 - 0.46 11.1 17.9 2.7 8.7 0.5 3.5 1 1 2 3 3 3 0 SlyX TMF_TATA_bd PF12325.8 EAX84109.1 - 0.49 10.6 24.8 0.39 10.9 17.3 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 EAX84109.1 - 0.51 10.3 29.3 0.68 9.9 3.6 3.4 1 1 1 2 2 2 0 Prefoldin subunit DUF87 PF01935.17 EAX84109.1 - 0.69 10.0 11.5 1.4 8.9 11.5 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF724 PF05266.14 EAX84109.1 - 0.71 9.7 24.6 0.65 9.8 14.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) T3SSipB PF16535.5 EAX84109.1 - 1.1 9.7 18.0 1.3 9.5 15.7 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB UPF0242 PF06785.11 EAX84109.1 - 1.2 9.2 32.9 0.19 11.8 17.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cluap1 PF10234.9 EAX84109.1 - 1.3 8.4 23.4 0.095 12.1 15.5 2.6 2 1 1 3 3 3 0 Clusterin-associated protein-1 TPR_MLP1_2 PF07926.12 EAX84109.1 - 1.7 8.7 28.6 52 3.9 28.6 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Med4 PF10018.9 EAX84109.1 - 1.9 8.1 18.5 2.2 7.9 11.5 2.7 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 ADIP PF11559.8 EAX84109.1 - 2.2 8.3 30.8 1.3 9.1 18.1 3.3 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 EAX84109.1 - 2.8 7.1 27.3 0.38 10.0 16.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 EAX84109.1 - 3.6 7.6 19.7 4.6 7.3 2.3 2.5 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 EAX84109.1 - 3.8 8.1 14.6 10 6.7 13.2 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 EAX84109.1 - 4.5 7.4 27.9 56 3.9 27.4 2.7 1 1 0 1 1 1 0 Tropomyosin like FapA PF03961.13 EAX84109.1 - 4.5 5.8 27.0 0.64 8.6 15.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4200 PF13863.6 EAX84109.1 - 4.8 7.6 26.9 10 6.6 3.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 EAX84109.1 - 5.1 6.9 24.2 2.6 7.9 3.1 3.8 1 1 1 2 2 1 0 Septum formation initiator LMBR1 PF04791.16 EAX84109.1 - 5.9 5.7 15.4 8.7 5.1 15.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MetOD2 PF18548.1 EAX84109.1 - 6.7 6.9 17.7 11 6.2 8.9 3.3 2 1 0 2 2 2 0 Metanogen output domain 2 Het-C PF07217.11 EAX84109.1 - 8.2 4.8 15.2 0.41 9.1 8.1 2.0 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C DHR10 PF18595.1 EAX84109.1 - 9.1 6.4 25.5 17 5.5 16.6 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4107 PF13389.6 EAX84110.1 - 2e-71 239.4 3.9 2.7e-71 239.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX84112.1 - 1.4e-152 506.1 13.8 1.7e-152 505.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84112.1 - 0.05 14.1 1.9 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84112.1 - 0.24 11.9 3.8 0.38 11.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX84112.1 - 0.28 11.5 2.8 17 5.8 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal DDR PF08841.10 EAX84114.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX84114.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX84115.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX84116.1 - 3.3e-156 517.9 13.8 4e-156 517.6 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX84116.1 - 0.22 11.9 3.0 11 6.4 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX84116.1 - 3.1 8.3 9.0 3.4 8.2 1.7 3.6 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX84117.1 - 8.2e-08 32.0 1.3 1e-07 31.7 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84117.1 - 0.0042 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84117.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84117.1 - 0.048 13.6 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DDR PF08841.10 EAX84120.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Myb_DNA-binding PF00249.31 EAX84123.1 - 5.3e-22 77.7 2.6 7.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX84123.1 - 4.3e-21 74.9 5.1 7.9e-13 48.5 1.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX84123.1 - 9.4e-05 22.5 1.7 0.0015 18.7 0.2 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX84123.1 - 0.00021 21.1 2.5 0.00023 21.0 0.1 2.1 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX84123.1 - 0.032 14.6 6.6 0.16 12.4 1.9 2.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain PilJ_C PF18223.1 EAX84123.1 - 0.076 13.5 1.6 0.13 12.8 1.4 1.4 1 1 0 1 1 1 0 Pili PilJ C-terminal domain Rap1_C PF11626.8 EAX84123.1 - 0.13 12.4 1.2 6.2 7.0 0.5 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EF-hand_13 PF17958.1 EAX84123.1 - 0.13 12.0 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain DUF3839 PF12943.7 EAX84124.1 - 2.4e-156 518.4 13.6 2.9e-156 518.1 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX84124.1 - 0.092 13.3 4.4 0.43 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX84124.1 - 0.22 12.0 6.0 2 8.9 1.0 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX84124.1 - 2.9 8.2 7.1 14 6.0 0.1 4.1 3 2 3 6 6 6 0 Tup N-terminal DUF3839 PF12943.7 EAX84125.1 - 5.5e-25 88.2 0.4 6.2e-25 88.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84126.1 - 6.8e-25 87.9 4.3 9.9e-25 87.4 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX84126.1 - 0.04 14.2 0.3 0.15 12.4 0.1 2.0 1 1 1 2 2 2 0 PRD domain Pox_A32 PF04665.12 EAX84127.1 - 6.6e-08 32.3 0.9 7.8e-08 32.1 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84127.1 - 0.0038 16.9 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84127.1 - 0.043 13.5 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84127.1 - 0.065 13.2 0.4 0.59 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) TPR_MLP1_2 PF07926.12 EAX84128.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX84128.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX84128.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DNA_pol_B_2 PF03175.13 EAX84129.1 - 6.1e-37 127.6 17.1 3.2e-36 125.2 17.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX84129.1 - 0.023 14.0 0.4 0.043 13.1 0.4 1.4 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF3839 PF12943.7 EAX84130.1 - 6.1e-147 487.5 10.6 8.4e-147 487.1 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX84130.1 - 0.0058 17.2 0.3 0.07 13.7 0.2 2.6 2 0 0 2 2 2 1 T5orf172 domain Fez1 PF06818.15 EAX84130.1 - 0.014 15.8 0.2 0.09 13.2 0.0 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84130.1 - 0.24 11.9 3.3 2.3 8.7 0.6 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84131.1 - 2.5e-154 511.7 13.9 3.1e-154 511.4 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84131.1 - 0.088 13.3 4.6 1.8 9.0 0.6 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84131.1 - 1.5 9.4 6.0 0.48 11.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX84132.1 - 3.9e-41 139.4 0.1 3.9e-41 139.4 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84132.1 - 0.014 15.5 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX84132.1 - 0.16 10.5 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX84133.1 - 8.2e-07 28.7 2.9 8.2e-07 28.7 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84133.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84133.1 - 4.7e-05 23.2 0.2 0.33 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84133.1 - 0.00012 22.2 3.1 0.00025 21.1 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84133.1 - 0.00061 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84133.1 - 0.0013 18.6 0.7 0.0024 17.7 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84133.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84133.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84133.1 - 0.071 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84133.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84133.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84133.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Trypan_PARP PF05887.11 EAX84135.1 - 0.037 14.0 11.1 0.052 13.5 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX84137.1 - 2.3e-117 390.7 14.6 2.8e-117 390.4 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84137.1 - 0.037 14.5 4.5 1.5 9.4 0.1 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX84137.1 - 0.062 13.6 0.6 0.19 12.0 0.2 2.2 2 1 0 2 2 2 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX84137.1 - 0.089 12.6 2.0 0.19 11.6 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF3839 PF12943.7 EAX84138.1 - 5.8e-111 369.7 8.0 6.5e-111 369.6 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX84138.1 - 0.071 12.6 0.8 0.098 12.1 0.7 1.3 1 1 0 1 1 1 0 Z1 domain Ank_2 PF12796.7 EAX84139.1 - 2.7e-70 232.9 4.1 5.4e-18 65.4 0.1 5.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX84139.1 - 1.2e-49 164.6 0.7 8.1e-06 26.1 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 EAX84139.1 - 1.3e-43 146.8 0.0 1.9e-08 34.7 0.0 7.5 6 2 1 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84139.1 - 6.6e-37 121.3 0.5 0.0026 18.1 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX84139.1 - 8.8e-35 118.3 0.9 3.5e-06 27.2 0.1 7.8 2 1 6 8 8 8 7 Ankyrin repeats (many copies) DUF4105 PF13387.6 EAX84139.1 - 0.00076 19.2 0.0 0.026 14.1 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4105) T4_Gp59_N PF08993.10 EAX84139.1 - 0.037 14.4 2.2 47 4.5 0.0 4.7 5 1 1 6 6 6 0 T4 gene Gp59 loader of gp41 DNA helicase Phage_T7_Capsid PF05396.11 EAX84139.1 - 0.21 11.9 0.8 12 6.3 0.1 3.2 3 1 0 4 4 4 0 Phage T7 capsid assembly protein DUF3839 PF12943.7 EAX84140.1 - 3.6e-154 511.2 12.8 4.4e-154 510.9 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84140.1 - 0.12 12.7 0.3 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84140.1 - 0.54 10.7 5.5 2.6 8.6 0.7 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84142.1 - 2.1e-16 59.7 0.2 3.8e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX84142.1 - 0.12 11.7 0.4 0.25 10.7 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX84143.1 - 3.8e-64 216.5 5.0 4.5e-64 216.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84144.1 - 3.3e-119 396.7 7.6 3.9e-119 396.5 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84145.1 - 1.7e-147 489.4 13.4 2e-147 489.1 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84145.1 - 1.7 9.2 5.1 4.2 7.9 0.1 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84145.1 - 1.7 9.2 4.4 1.2 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX84146.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84146.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84146.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84146.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84146.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84146.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84146.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84146.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84146.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84146.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84146.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84146.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TPR_MLP1_2 PF07926.12 EAX84148.1 - 0.004 17.2 1.2 0.005 16.9 1.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF641 PF04859.12 EAX84149.1 - 0.032 14.6 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX84149.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor Sin3a_C PF16879.5 EAX84151.1 - 0.0015 18.3 2.6 0.0021 17.9 2.6 1.3 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein Hexose_dehydrat PF03559.14 EAX84151.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase CpxA_peri PF16527.5 EAX84151.1 - 0.064 13.6 3.5 0.31 11.4 1.3 2.1 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain SbcD_C PF12320.8 EAX84151.1 - 0.1 12.9 2.1 0.17 12.2 2.1 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Syntaxin_2 PF14523.6 EAX84151.1 - 0.13 12.6 3.1 0.19 12.1 1.4 1.9 2 0 0 2 2 2 0 Syntaxin-like protein APG6_N PF17675.1 EAX84151.1 - 0.36 11.3 8.5 0.61 10.6 8.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Amidase02_C PF12123.8 EAX84153.1 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX84154.1 - 2.4e-71 239.1 3.2 3.2e-71 238.7 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84154.1 - 0.061 13.7 0.1 0.14 12.6 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta DUF2939 PF11159.8 EAX84158.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84158.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ribosomal_S13 PF00416.22 EAX84159.1 - 1.2e-35 122.6 0.4 1.4e-35 122.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 EAX84159.1 - 0.0097 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Ank_2 PF12796.7 EAX84160.1 - 6.1e-40 135.7 16.8 1.9e-09 38.0 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84160.1 - 6.2e-30 103.2 3.8 5.8e-07 29.9 0.0 7.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84160.1 - 7e-25 84.4 11.5 0.081 13.5 0.0 12.5 13 1 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 EAX84160.1 - 8.9e-22 76.9 5.3 0.00013 22.2 0.0 8.8 4 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX84160.1 - 7.3e-17 61.0 0.1 5.1e-05 23.5 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat DUF3447 PF11929.8 EAX84160.1 - 9.9e-08 31.8 11.7 1.1e-06 28.5 0.2 4.5 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) FBD PF08387.10 EAX84160.1 - 0.11 12.4 1.7 57 3.7 0.0 4.5 5 0 0 5 5 5 0 FBD LRR_9 PF14580.6 EAX84161.1 - 7.6e-06 25.5 0.0 8.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat Rota_NSP4 PF01452.16 EAX84161.1 - 0.0072 16.0 0.0 0.0074 16.0 0.0 1.0 1 0 0 1 1 1 1 Rotavirus non structural protein LRR_4 PF12799.7 EAX84161.1 - 0.08 13.4 2.5 1.1 9.8 0.1 2.3 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) FAS_N PF17828.1 EAX84162.1 - 0.0054 16.7 0.1 0.0074 16.3 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX84163.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84163.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX84165.1 - 2.1e-80 269.7 10.5 2.7e-80 269.3 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX84165.1 - 0.038 14.6 0.4 0.069 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX84165.1 - 0.13 12.6 1.6 0.27 11.6 0.1 2.2 3 0 0 3 3 3 0 PRD domain GalP_UDP_transf PF01087.22 EAX84165.1 - 0.27 11.6 1.6 1.2 9.5 0.8 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Gly_rich PF12810.7 EAX84166.1 - 3.5e-28 99.2 9.8 4.5e-28 98.8 9.8 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX84167.1 - 1.7e-32 113.3 24.0 2e-32 113.0 24.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX84168.1 - 1.3e-48 166.1 29.9 1.5e-48 165.8 29.9 1.1 1 0 0 1 1 1 1 Glycine rich protein Amidase02_C PF12123.8 EAX84169.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Chlam_PMP PF02415.17 EAX84170.1 - 0.76 10.4 39.4 0.4 11.3 0.7 7.7 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4064 PF13273.6 EAX84171.1 - 0.00024 21.3 0.3 0.00029 21.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) TMEM154 PF15102.6 EAX84171.1 - 0.00033 20.6 0.9 0.0004 20.3 0.9 1.1 1 0 0 1 1 1 1 TMEM154 protein family Collectrin PF16959.5 EAX84171.1 - 0.00039 20.2 1.0 0.00045 20.0 1.0 1.0 1 0 0 1 1 1 1 Renal amino acid transporter Stevor PF17410.2 EAX84171.1 - 0.00097 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 EAX84171.1 - 0.0013 18.5 0.3 0.0015 18.3 0.3 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein ODV-E18 PF10717.9 EAX84171.1 - 0.0019 18.0 2.8 0.0033 17.3 2.8 1.4 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF5305 PF17231.2 EAX84171.1 - 0.003 17.0 0.4 0.0036 16.7 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Orf78 PF06024.12 EAX84171.1 - 0.0031 17.8 0.1 0.0037 17.5 0.1 1.1 1 0 0 1 1 1 1 Orf78 (ac78) Shisa PF13908.6 EAX84171.1 - 0.0033 17.7 0.4 0.0036 17.6 0.4 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4690 PF15756.5 EAX84171.1 - 0.0041 17.7 0.3 0.0053 17.3 0.3 1.2 1 0 0 1 1 1 1 Small Novel Rich in Cartilage RIFIN PF02009.16 EAX84171.1 - 0.007 16.3 1.4 0.0079 16.1 1.4 1.1 1 0 0 1 1 1 1 Rifin DUF4448 PF14610.6 EAX84171.1 - 0.0087 15.8 0.5 0.0099 15.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF997 PF06196.12 EAX84171.1 - 0.0088 16.0 0.7 0.011 15.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF997) UL42 PF17638.2 EAX84171.1 - 0.012 15.6 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 HCMV UL42 LRRC37AB_C PF14914.6 EAX84171.1 - 0.012 15.5 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Rhabdo_glycop PF00974.18 EAX84171.1 - 0.015 13.8 0.1 0.015 13.8 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein CrgA PF06781.12 EAX84171.1 - 0.017 15.2 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Cell division protein CrgA DUF2207 PF09972.9 EAX84171.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 EAX84171.1 - 0.019 15.2 0.1 0.022 15.0 0.1 1.1 1 0 0 1 1 1 0 Glycophorin A Baculo_F PF12259.8 EAX84171.1 - 0.024 13.2 0.1 0.024 13.2 0.1 1.0 1 0 0 1 1 1 0 Baculovirus F protein DUF4366 PF14283.6 EAX84171.1 - 0.031 14.3 0.2 0.04 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EAX84171.1 - 0.037 12.9 0.3 0.042 12.7 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FeoB_associated PF12669.7 EAX84171.1 - 0.06 13.8 9.6 0.099 13.1 9.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3827 PF12877.7 EAX84171.1 - 0.062 11.7 0.5 0.061 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 EAX84171.1 - 0.13 13.1 5.7 0.25 12.2 5.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAX84171.1 - 0.16 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless Gemini_mov PF01708.16 EAX84171.1 - 0.38 10.5 2.1 0.56 10.0 1.5 1.7 1 1 0 1 1 1 0 Geminivirus putative movement protein Syndecan PF01034.20 EAX84171.1 - 0.49 10.4 4.0 0.88 9.5 4.0 1.4 1 0 0 1 1 1 0 Syndecan domain TMIE PF16038.5 EAX84171.1 - 0.51 10.2 3.6 0.26 11.1 1.0 1.7 2 0 0 2 2 2 0 TMIE protein DUF5385 PF17359.2 EAX84171.1 - 0.52 9.8 4.7 0.18 11.3 2.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Baculo_11_kDa PF06143.11 EAX84171.1 - 0.88 9.2 8.0 0.62 9.7 4.8 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Peptidase_S49_N PF08496.10 EAX84171.1 - 1.5 8.9 4.5 3.1 7.9 2.4 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Protocadherin PF08374.11 EAX84171.1 - 1.8 8.5 5.3 2 8.3 5.3 1.3 1 1 0 1 1 1 0 Protocadherin RCR PF12273.8 EAX84171.1 - 2.2 8.9 5.7 0.57 10.8 2.6 1.5 2 0 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red DUF929 PF06053.11 EAX84171.1 - 7.5 5.8 7.8 11 5.2 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Pox_A32 PF04665.12 EAX84173.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84173.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84173.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84173.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Trypan_PARP PF05887.11 EAX84174.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84174.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX84175.1 - 0.03 14.7 0.6 0.036 14.5 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX84176.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) T2SSS_2 PF16549.5 EAX84177.1 - 0.022 14.7 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS) pilotin, S protein DUF4107 PF13389.6 EAX84179.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX84180.1 - 2e-10 41.0 1.4 2.4e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX84180.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Pox_A32 PF04665.12 EAX84181.1 - 3.1e-07 30.1 1.9 4.1e-07 29.7 1.9 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84181.1 - 0.0067 16.1 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84181.1 - 0.095 12.4 0.1 0.32 10.7 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX84181.1 - 1.1 9.5 8.1 7.4 6.8 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX84182.1 - 4.5e-41 139.2 0.7 9.2e-41 138.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84182.1 - 0.062 13.9 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX84183.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain EpuA PF11772.8 EAX84191.1 - 0.017 14.8 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta KilA-N PF04383.13 EAX84193.1 - 3.9e-10 39.6 0.2 4.8e-10 39.3 0.2 1.2 1 1 0 1 1 1 1 KilA-N domain Glyco_hydro_88 PF07470.13 EAX84195.1 - 0.15 11.1 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DUF3839 PF12943.7 EAX84197.1 - 1.1e-149 496.5 11.2 1.3e-149 496.3 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84197.1 - 0.047 13.9 0.4 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 Rx_N PF18052.1 EAX84197.1 - 0.074 13.3 0.4 1.2 9.5 0.1 2.8 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84197.1 - 0.51 10.8 4.8 3.3 8.2 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4483 PF14825.6 EAX84200.1 - 1.3e-31 109.6 0.3 1.5e-31 109.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Pox_A32 PF04665.12 EAX84201.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84201.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84201.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84201.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) T5orf172 PF10544.9 EAX84203.1 - 2.5e-06 27.9 0.1 5.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84203.1 - 0.0084 15.9 0.2 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX84203.1 - 0.011 15.3 0.2 0.039 13.5 0.1 1.8 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84204.1 - 6.8e-154 510.3 14.9 8.4e-154 510.0 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84204.1 - 0.11 13.0 3.1 0.18 12.2 1.0 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX84204.1 - 0.19 12.1 1.3 1.2 9.6 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX84204.1 - 0.32 10.8 2.1 0.69 9.8 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84204.1 - 1.3 9.6 9.7 2.1 8.8 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84204.1 - 5.6 7.5 6.9 0.97 10.0 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX84205.1 - 5.1e-144 478.0 9.0 6e-144 477.7 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX84205.1 - 0.35 11.4 3.9 2.6 8.6 0.1 2.7 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX84205.1 - 1.7 9.2 6.4 2.1 8.9 1.2 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 EAX84206.1 - 6.9e-56 186.8 35.5 1.1e-14 54.8 1.8 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84206.1 - 3e-51 171.2 17.6 1.4e-12 47.8 0.1 6.7 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX84206.1 - 1.3e-49 164.5 15.4 5.9e-06 26.5 0.1 8.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 EAX84206.1 - 1.4e-44 145.0 11.9 6.9e-05 23.0 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX84206.1 - 1.2e-40 137.0 19.1 2e-10 40.7 0.5 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX84206.1 - 0.011 15.9 7.2 5.7 7.2 0.2 5.5 5 2 2 7 7 7 0 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX84206.1 - 0.025 14.9 0.7 4.8 7.5 0.0 3.6 1 1 3 4 4 4 0 Pleckstrin homology domain Mago_nashi PF02792.14 EAX84206.1 - 0.055 13.6 0.3 0.37 10.9 0.3 2.3 2 1 0 2 2 2 0 Mago nashi protein Chi-conotoxin PF16981.5 EAX84206.1 - 0.19 12.0 0.3 5.5 7.3 0.0 3.0 4 0 0 4 4 4 0 chi-Conotoxin or t superfamily RasGAP PF00616.19 EAX84207.1 - 1.1e-10 41.6 0.3 2.4e-08 33.9 0.1 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CtsR_C PF17727.1 EAX84207.1 - 0.077 13.1 0.8 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain DUF3052 PF11253.8 EAX84208.1 - 0.24 11.3 2.6 1.9 8.4 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3052) DUF2897 PF11446.8 EAX84208.1 - 0.42 10.5 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_D5 PF03288.16 EAX84209.1 - 1.1e-05 25.8 0.6 1.6e-05 25.3 0.6 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX84209.1 - 0.0083 16.7 0.1 0.011 16.3 0.1 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX84209.1 - 0.026 14.5 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX84210.1 - 2.5e-11 43.4 0.0 4.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain D5_N PF08706.11 EAX84210.1 - 0.087 13.1 1.6 0.47 10.7 1.2 2.1 1 1 1 2 2 2 0 D5 N terminal like Chal_sti_synt_N PF00195.19 EAX84210.1 - 0.15 11.4 0.4 0.33 10.3 0.4 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX84210.1 - 6.1 6.7 7.6 16 5.3 7.6 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3839 PF12943.7 EAX84211.1 - 1.8e-25 89.8 3.9 2.6e-25 89.3 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX84211.1 - 0.031 13.4 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3839 PF12943.7 EAX84212.1 - 6.7e-27 94.5 0.3 7.3e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84213.1 - 3.1e-116 387.0 11.8 3.9e-116 386.7 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84213.1 - 0.047 13.6 1.4 0.13 12.1 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX84214.1 - 7.4e-05 23.2 0.2 0.00021 21.8 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX84214.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX84214.1 - 0.017 14.7 1.0 0.19 11.2 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX84214.1 - 0.045 13.6 0.1 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain T5orf172 PF10544.9 EAX84215.1 - 5.1e-07 30.2 0.3 1.3e-06 28.9 0.3 1.6 1 1 0 1 1 1 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX84215.1 - 0.003 16.9 0.0 0.0061 15.8 0.0 1.5 2 0 0 2 2 2 1 Baculoviridae ME53 KilA-N PF04383.13 EAX84215.1 - 0.017 15.0 0.8 0.07 13.0 0.1 2.2 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX84215.1 - 0.11 12.0 1.0 1.3 8.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84216.1 - 1.2e-156 519.4 12.2 1.4e-156 519.1 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84216.1 - 0.26 11.8 6.6 2.4 8.7 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX84216.1 - 0.8 10.1 5.0 9.2 6.7 0.1 3.8 4 1 0 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX84217.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84217.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84217.1 - 4.8e-05 23.2 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84217.1 - 0.00011 22.3 2.8 0.00028 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84217.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84217.1 - 0.0011 18.8 0.6 0.002 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84217.1 - 0.0012 18.5 0.4 0.0095 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84217.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84217.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84217.1 - 0.088 13.2 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84217.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84217.1 - 0.39 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX84219.1 - 4.5e-08 32.9 0.9 5.3e-08 32.6 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84219.1 - 0.0023 17.6 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84219.1 - 0.041 13.6 0.1 0.1 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84219.1 - 0.1 12.6 0.4 0.99 9.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX84220.1 - 5.9e-33 113.1 0.7 1.1e-32 112.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX84220.1 - 0.1 13.3 1.4 18 6.1 0.2 3.2 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3839 PF12943.7 EAX84221.1 - 7.4e-155 513.5 10.8 9.2e-155 513.2 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX84221.1 - 0.03 14.6 0.7 11 6.4 0.1 3.7 3 1 1 4 4 4 0 Tup N-terminal Fez1 PF06818.15 EAX84221.1 - 0.035 14.6 1.1 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84221.1 - 0.15 12.6 4.8 1.6 9.3 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX84221.1 - 0.24 11.7 3.5 0.54 10.6 0.1 2.9 2 2 1 3 3 3 0 PRD domain DUF2408 PF10303.9 EAX84221.1 - 0.48 11.0 5.8 0.16 12.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TBCC PF07986.12 EAX84222.1 - 7.7e-36 122.5 9.3 1.1e-35 122.0 9.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EAX84222.1 - 0.00091 18.9 4.4 0.0014 18.3 4.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DHC_N2 PF08393.13 EAX84223.1 - 2.3e-45 155.4 7.3 2.3e-45 155.4 7.3 3.9 3 2 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 PTH2 PF01981.16 EAX84223.1 - 0.29 11.4 1.1 1 9.7 0.3 2.4 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Baculo_PEP_C PF04513.12 EAX84223.1 - 3.7 7.6 29.5 0.26 11.3 2.0 5.8 5 2 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI_PP_I PF18363.1 EAX84223.1 - 7.9 6.7 13.6 1.2 9.4 1.5 4.5 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain GPS2_interact PF15784.5 EAX84225.1 - 0.05 14.0 1.3 0.067 13.6 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84225.1 - 0.14 11.1 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Glyco_hydro_47 PF01532.20 EAX84227.1 - 7e-09 35.1 0.0 9.7e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4107 PF13389.6 EAX84230.1 - 1.3e-67 227.0 2.7 1.7e-67 226.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX84231.1 - 6.1e-150 497.4 10.8 7.4e-150 497.1 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84231.1 - 0.032 14.5 1.2 1.6 9.1 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain Pox_D5 PF03288.16 EAX84232.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX84233.1 - 1.5e-61 206.5 6.1 1.6e-61 206.4 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX84235.1 - 2.9e-157 521.4 13.7 3.6e-157 521.0 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84235.1 - 0.035 14.6 2.2 0.13 12.7 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84235.1 - 0.23 11.9 5.8 2.1 8.9 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84235.1 - 0.83 10.2 6.6 0.19 12.3 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX84235.1 - 0.91 9.9 5.8 14 6.1 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal Pox_A32 PF04665.12 EAX84236.1 - 7e-07 28.9 2.3 7e-07 28.9 2.3 2.2 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84236.1 - 9e-05 22.8 0.3 0.00065 20.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84236.1 - 0.00021 21.1 0.6 0.42 10.3 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX84236.1 - 0.00093 19.0 0.1 0.0018 18.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX84236.1 - 0.0016 18.5 5.5 0.0027 17.8 4.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX84236.1 - 0.0052 16.5 2.8 0.015 14.9 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX84236.1 - 0.039 13.7 1.8 0.084 12.6 1.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX84236.1 - 0.042 14.2 0.0 0.09 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX84236.1 - 0.082 13.0 0.7 1.3 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX84236.1 - 0.12 11.9 0.0 0.39 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX84236.1 - 0.21 11.8 4.3 3.9 7.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX84236.1 - 0.9 10.2 11.7 0.42 11.3 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF3839 PF12943.7 EAX84237.1 - 1.8e-137 456.5 10.6 2.3e-137 456.2 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84237.1 - 0.051 14.0 0.5 0.55 10.7 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function zf_CopZ PF18423.1 EAX84237.1 - 0.15 12.1 0.4 0.15 12.1 0.4 2.0 2 0 0 2 2 2 0 Zinc binding domain KELK PF15796.5 EAX84237.1 - 0.35 11.3 9.2 0.9 10.0 2.8 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf-C4pol PF14260.6 EAX84237.1 - 0.48 10.9 4.4 3.9 8.0 0.1 2.8 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF3839 PF12943.7 EAX84238.1 - 5e-141 468.2 14.1 1.5e-140 466.6 14.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84238.1 - 1.5 9.4 4.8 4.9 7.7 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84239.1 - 2.1e-06 28.2 0.1 4.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84239.1 - 0.006 16.4 0.3 0.031 14.1 0.1 2.2 2 1 0 2 2 2 1 KilA-N domain Shisa PF13908.6 EAX84240.1 - 0.00014 22.1 0.0 0.00018 21.8 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 EAX84240.1 - 0.0076 16.5 0.1 0.017 15.4 0.1 1.7 1 1 1 2 2 2 1 Glycophorin A MBDa PF16564.5 EAX84240.1 - 0.14 12.4 0.9 0.33 11.2 0.5 1.9 2 0 0 2 2 2 0 p55-binding region of Methyl-CpG-binding domain proteins MBD CYYR1 PF10873.8 EAX84240.1 - 1.1 9.7 8.7 6.1 7.3 8.4 2.4 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 EAX84242.1 - 5.6e-08 33.2 3.7 6.3e-08 33.1 3.7 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Prominin PF05478.11 EAX84242.1 - 2.5e-05 22.5 0.1 2.7e-05 22.4 0.1 1.0 1 0 0 1 1 1 1 Prominin TMEM52 PF14979.6 EAX84242.1 - 2.8e-05 24.1 0.1 4.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Transmembrane 52 Comm PF15957.5 EAX84242.1 - 0.00015 22.1 1.4 0.00015 22.1 1.4 1.7 2 0 0 2 2 2 1 Commissureless EphA2_TM PF14575.6 EAX84242.1 - 0.00029 21.6 0.1 0.00048 21.0 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 EAX84242.1 - 0.0006 19.6 1.4 0.00084 19.1 1.4 1.3 1 0 0 1 1 1 1 TMIE protein SIT PF15330.6 EAX84242.1 - 0.0031 17.9 0.4 0.0057 17.1 0.4 1.5 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 EAX84242.1 - 0.0041 18.1 0.0 0.0077 17.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Mucin PF01456.17 EAX84242.1 - 0.0041 17.1 3.1 0.0041 17.1 3.1 1.5 1 1 1 2 2 2 1 Mucin-like glycoprotein Rhabdo_glycop PF00974.18 EAX84242.1 - 0.0042 15.6 0.2 0.0051 15.3 0.2 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein SARAF PF06682.12 EAX84242.1 - 0.0045 16.7 1.4 0.0062 16.2 1.0 1.4 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis NS3_envE PF02723.14 EAX84242.1 - 0.005 16.9 2.6 0.0084 16.2 2.6 1.3 1 0 0 1 1 1 1 Non-structural protein NS3/Small envelope protein E VSP PF03302.13 EAX84242.1 - 0.007 15.3 1.7 0.0089 14.9 1.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein ECSCR PF15820.5 EAX84242.1 - 0.0072 16.1 1.3 0.011 15.5 1.3 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator LAT PF15234.6 EAX84242.1 - 0.011 15.5 1.0 0.015 15.0 1.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells SCIMP PF15050.6 EAX84242.1 - 0.014 15.9 0.2 0.021 15.3 0.2 1.3 1 0 0 1 1 1 0 SCIMP protein Baculo_F PF12259.8 EAX84242.1 - 0.022 13.3 0.2 0.022 13.3 0.2 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF997 PF06196.12 EAX84242.1 - 0.028 14.4 1.7 0.049 13.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) HemY_N PF07219.13 EAX84242.1 - 0.035 14.3 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus MAP17 PF15807.5 EAX84242.1 - 0.044 14.0 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Corona_S2 PF01601.16 EAX84242.1 - 0.066 11.7 3.2 0.082 11.4 3.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 EAX84242.1 - 0.095 13.4 7.5 0.24 12.0 7.5 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Stevor PF17410.2 EAX84242.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3328 PF11807.8 EAX84242.1 - 0.12 12.1 5.1 0.11 12.3 3.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Orf78 PF06024.12 EAX84242.1 - 0.57 10.5 2.7 0.45 10.9 0.5 1.8 1 1 1 2 2 2 0 Orf78 (ac78) Pox_EPC_I2-L1 PF12575.8 EAX84242.1 - 0.91 9.8 3.6 0.25 11.6 0.6 1.6 2 0 0 2 2 1 0 Poxvirus entry protein complex L1 and I2 DUF4690 PF15756.5 EAX84242.1 - 1.5 9.4 4.7 0.49 11.0 0.9 2.0 1 1 1 2 2 2 0 Small Novel Rich in Cartilage DUF4083 PF13314.6 EAX84242.1 - 2.8 8.0 8.4 7.8 6.5 8.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4083) PDDEXK_3 PF13366.6 EAX84243.1 - 0.019 15.3 0.8 0.035 14.5 0.1 1.7 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily BsuBI_PstI_RE_N PF17728.1 EAX84243.1 - 0.062 13.2 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain Prim-Pol PF09250.11 EAX84243.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal PTR PF12789.7 EAX84244.1 - 3.5e-163 529.8 128.2 7.7e-33 112.3 14.8 7.2 3 2 5 8 8 8 6 Phage tail repeat like Tis11B_N PF04553.12 EAX84244.1 - 0.075 13.6 4.6 6.3 7.4 0.6 2.9 1 1 1 2 2 2 0 Tis11B like protein, N terminus Apolipoprotein PF01442.18 EAX84244.1 - 0.14 12.0 4.7 0.41 10.5 2.6 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain SAS4 PF15460.6 EAX84244.1 - 1.2 9.3 18.4 20 5.3 1.8 4.7 2 1 4 6 6 6 0 Something about silencing, SAS, complex subunit 4 DUF2785 PF10978.8 EAX84244.1 - 1.9 8.2 14.3 3.8 7.3 6.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) DUF3781 PF12636.7 EAX84245.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX84246.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX84246.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Chlam_PMP PF02415.17 EAX84248.1 - 0.035 14.6 0.7 0.035 14.6 0.7 7.8 8 1 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PMP1_2 PF08114.11 EAX84248.1 - 0.061 13.1 1.0 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family TMEM132D_C PF15706.5 EAX84248.1 - 0.13 12.0 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4774 PF15999.5 EAX84248.1 - 4.4 7.2 5.6 4.2 7.3 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4774) DUF3781 PF12636.7 EAX84252.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX84253.1 - 5e-66 221.8 13.2 1.4e-64 217.1 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84253.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF4106 PF13388.6 EAX84254.1 - 6.2e-271 898.7 20.4 7.3e-271 898.4 20.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX84254.1 - 0.00087 19.6 0.2 0.037 14.3 0.3 2.6 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX84254.1 - 0.032 14.0 0.2 0.075 12.8 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF4108 PF13390.6 EAX84255.1 - 7.4e-61 204.3 8.3 8.3e-61 204.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX84257.1 - 2.8e-07 30.3 2.7 2.8e-07 30.3 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84257.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84257.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84257.1 - 0.00017 21.6 3.5 0.00041 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84257.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84257.1 - 0.0015 18.3 0.7 0.003 17.4 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84257.1 - 0.0017 18.0 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84257.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84257.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84257.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84257.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84257.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84258.1 - 8e-26 90.1 1.4 1.1e-25 89.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84258.1 - 0.083 13.5 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX84258.1 - 0.11 13.2 2.0 13 6.6 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF4108 PF13390.6 EAX84259.1 - 8.7e-54 181.3 7.7 9.7e-54 181.2 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ATP-synt_E PF05680.12 EAX84260.1 - 1.7 9.0 9.1 4 7.8 9.1 1.6 1 0 0 1 1 1 0 ATP synthase E chain Pox_A32 PF04665.12 EAX84261.1 - 6.1e-07 29.1 2.4 6.1e-07 29.1 2.4 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84261.1 - 3.1e-05 24.3 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84261.1 - 4.2e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84261.1 - 0.00014 21.9 3.8 0.00034 20.6 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84261.1 - 0.00094 19.0 0.1 0.0017 18.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84261.1 - 0.0019 18.1 0.8 0.0039 17.0 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84261.1 - 0.002 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84261.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84261.1 - 0.075 12.6 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX84261.1 - 0.086 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84261.1 - 0.11 12.9 0.1 0.89 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84261.1 - 0.23 11.8 4.9 3.2 8.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX84262.1 - 7.4e-155 513.5 15.6 9e-155 513.2 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84262.1 - 0.08 13.4 2.1 0.29 11.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84262.1 - 0.41 11.1 7.7 2.2 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84262.1 - 0.89 10.1 6.0 0.33 11.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX84263.1 - 2.8e-05 24.1 0.6 2.8e-05 24.1 0.6 4.4 3 1 1 4 4 4 1 Phage tail repeat like DUF3417 PF11897.8 EAX84263.1 - 0.035 14.6 1.2 0.15 12.5 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX84263.1 - 0.043 13.6 5.9 0.065 13.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX84263.1 - 0.089 12.5 0.3 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX84263.1 - 0.17 11.4 17.7 0.04 13.5 7.6 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) TPR_MLP1_2 PF07926.12 EAX84264.1 - 0.012 15.7 0.8 0.015 15.4 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX84264.1 - 0.44 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF2316 PF10078.9 EAX84266.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) TerB_N PF13208.6 EAX84267.1 - 0.031 14.0 0.1 0.037 13.7 0.1 1.0 1 0 0 1 1 1 0 TerB N-terminal domain Imm40 PF15569.6 EAX84268.1 - 0.048 13.8 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Immunity protein 40 NRDE-2 PF08424.10 EAX84268.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF3839 PF12943.7 EAX84269.1 - 5.7e-157 520.4 14.3 7.2e-157 520.0 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84269.1 - 0.55 10.7 6.2 2.1 8.8 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX84270.1 - 7.1e-08 32.2 1.1 8.6e-08 31.9 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84270.1 - 0.0041 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84270.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84270.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Syja_N PF02383.18 EAX84271.1 - 0.098 12.0 0.3 0.11 11.8 0.3 1.0 1 0 0 1 1 1 0 SacI homology domain Chal_sti_synt_N PF00195.19 EAX84271.1 - 0.21 11.0 0.6 0.4 10.1 0.6 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX84271.1 - 6.1 6.7 9.0 15 5.4 9.0 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA KilA-N PF04383.13 EAX84272.1 - 4.2e-09 36.2 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain FAS_N PF17828.1 EAX84273.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX84273.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX84274.1 - 0.0015 18.9 0.7 0.0023 18.3 0.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX84274.1 - 0.084 12.8 0.2 0.086 12.8 0.2 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX84274.1 - 1.7 8.7 6.2 1.9 8.5 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX84275.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Trypan_PARP PF05887.11 EAX84276.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX84277.1 - 9.3e-158 523.0 15.0 1.1e-157 522.7 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84277.1 - 0.072 12.9 1.2 0.23 11.3 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX84277.1 - 0.096 13.1 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Rx_N PF18052.1 EAX84277.1 - 0.18 12.1 0.9 4.2 7.7 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84277.1 - 0.23 11.9 4.2 2 8.9 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84278.1 - 4.1e-05 24.1 0.1 0.00011 22.7 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX84278.1 - 0.11 12.0 0.5 0.64 9.5 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84279.1 - 6.8e-135 448.1 12.6 7.6e-135 447.9 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84280.1 - 1.3e-154 512.6 12.4 1.6e-154 512.4 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84280.1 - 0.19 12.0 5.0 1.4 9.2 0.0 3.3 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX84280.1 - 0.51 10.8 7.0 1.8 9.0 0.8 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX84280.1 - 1 10.0 3.9 0.77 10.4 0.2 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5398) Mito_fiss_reg PF05308.11 EAX84281.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX84281.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX84283.1 - 2.5e-40 136.8 0.1 4.4e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain ARA70 PF12489.8 EAX84284.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Adeno_E3 PF06040.11 EAX84286.1 - 0.04 14.1 0.2 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein Adeno_E3B PF03376.14 EAX84286.1 - 0.88 9.9 6.3 8.5 6.7 0.6 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein DUF3839 PF12943.7 EAX84287.1 - 5e-122 406.0 14.1 6.3e-122 405.6 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84287.1 - 0.11 13.0 3.3 1.8 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84288.1 - 1.7e-06 28.5 0.6 5.2e-06 26.9 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Pox_A32 PF04665.12 EAX84289.1 - 3.5e-07 30.0 2.8 3.7e-07 29.9 1.2 1.8 2 1 0 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX84289.1 - 4.2e-06 26.9 2.0 9.8e-06 25.7 2.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84289.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX84289.1 - 6e-05 23.3 0.2 0.00036 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84289.1 - 7.9e-05 22.5 0.1 0.4 10.4 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein Zot PF05707.12 EAX84289.1 - 0.0012 18.5 0.3 0.017 14.8 0.1 2.2 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX84289.1 - 0.0025 17.6 0.4 0.0049 16.7 0.4 1.7 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EAX84289.1 - 0.0036 17.0 0.3 0.0071 16.0 0.2 1.4 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 EAX84289.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84289.1 - 0.074 12.6 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX84289.1 - 0.08 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX84289.1 - 0.1 13.0 0.0 0.46 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84289.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DNA_pol_B_2 PF03175.13 EAX84291.1 - 2.4e-08 33.3 0.1 3.4e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX84291.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF4106 PF13388.6 EAX84292.1 - 7.1e-269 891.9 21.5 7.1e-269 891.9 21.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3112 PF11309.8 EAX84292.1 - 0.072 12.5 0.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) KAR PF15222.6 EAX84292.1 - 0.074 13.3 0.9 1.6 9.1 0.2 2.9 3 0 0 3 3 3 0 Kidney androgen-regulated DUF3839 PF12943.7 EAX84293.1 - 2.7e-156 518.2 13.4 3.4e-156 517.8 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84293.1 - 0.022 15.0 1.1 0.047 13.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX84293.1 - 0.21 12.1 5.4 1.8 9.0 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84293.1 - 0.35 11.4 6.2 0.21 12.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5398 PF17376.2 EAX84293.1 - 0.39 11.4 5.2 0.41 11.3 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5398) T5orf172 PF10544.9 EAX84294.1 - 0.0013 19.3 0.2 0.0025 18.3 0.2 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84294.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX84294.1 - 0.057 13.0 0.2 0.086 12.4 0.2 1.3 1 0 0 1 1 1 0 Legume lectin domain Pox_A32 PF04665.12 EAX84295.1 - 4e-06 26.5 2.2 5.7e-06 26.0 2.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84295.1 - 0.0042 16.7 0.2 0.0053 16.4 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX84295.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX84295.1 - 0.061 13.1 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX84295.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX84295.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX84295.1 - 0.61 10.3 8.4 5.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX84296.1 - 7.6e-25 87.8 3.5 1.2e-24 87.1 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX84296.1 - 0.055 13.8 1.6 0.26 11.6 0.1 2.2 1 1 1 2 2 2 0 PRD domain DUF3781 PF12636.7 EAX84297.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX84298.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84299.1 - 0.18 10.8 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX84300.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84300.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 EAX84301.1 - 2.2e-56 191.1 0.1 3.1e-56 190.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84301.1 - 3.1e-39 134.8 0.1 3.8e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX84301.1 - 2.8e-10 40.0 0.1 2.7e-08 33.5 0.0 2.8 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EAX84301.1 - 0.0045 16.0 0.4 0.0085 15.1 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Metallophos PF00149.28 EAX84302.1 - 7.9e-22 78.8 0.1 2.6e-21 77.1 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Trypan_PARP PF05887.11 EAX84304.1 - 0.11 12.5 8.4 0.17 11.9 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84304.1 - 2.7 8.4 6.0 3.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX84305.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84305.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX84307.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX84308.1 - 2e-73 245.9 4.7 2.4e-73 245.7 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX84308.1 - 0.082 11.3 1.0 0.12 10.8 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1731 PF08338.11 EAX84309.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Bromodomain PF00439.25 EAX84310.1 - 5.8e-05 23.1 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain KfrA_N PF11740.8 EAX84310.1 - 0.01 16.5 0.0 0.012 16.2 0.0 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Glyco_transf_28 PF03033.20 EAX84310.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain YtxH PF12732.7 EAX84310.1 - 5.2 7.7 6.0 30 5.2 6.0 2.1 1 1 0 1 1 1 0 YtxH-like protein CLPTM1 PF05602.12 EAX84311.1 - 4.7e-26 91.8 5.1 9.3e-26 90.8 5.1 1.5 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EAX84311.1 - 5.2e-09 35.7 5.2 2e-06 27.5 3.9 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF4912 PF16258.5 EAX84311.1 - 0.028 14.6 0.1 0.087 13.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) SecB PF02556.14 EAX84311.1 - 0.089 12.7 0.0 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit SecB DUF3839 PF12943.7 EAX84312.1 - 2.1e-157 521.8 13.7 2.6e-157 521.5 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84312.1 - 2.7 8.5 7.9 1.5 9.3 0.5 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX84313.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX84314.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX84314.1 - 8.8 6.3 6.6 20 5.2 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX84315.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84315.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84315.1 - 4.1e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84315.1 - 0.00014 21.9 3.4 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84315.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84315.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84315.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84315.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84315.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84315.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84315.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84315.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84316.1 - 3e-40 136.6 1.0 5e-40 135.8 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX84316.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX84317.1 - 2.4e-06 28.0 0.0 5.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84317.1 - 0.0065 16.3 0.9 0.043 13.7 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX84317.1 - 0.01 15.4 0.2 0.036 13.6 0.1 1.8 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84318.1 - 6.2e-147 487.5 14.4 8.3e-147 487.1 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84318.1 - 0.007 16.8 1.0 0.031 14.7 0.1 2.0 2 0 0 2 2 2 1 Fez1 Lectin_legB PF00139.19 EAX84318.1 - 0.029 13.9 0.3 0.049 13.2 0.3 1.3 1 0 0 1 1 1 0 Legume lectin domain NTP_transf_6 PF06042.11 EAX84318.1 - 0.063 13.1 1.2 0.21 11.4 0.6 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase CENP-F_leu_zip PF10473.9 EAX84318.1 - 0.081 13.0 4.7 3.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GCN5L1 PF06320.13 EAX84318.1 - 0.091 12.9 0.7 0.51 10.5 0.2 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF4094 PF13334.6 EAX84318.1 - 0.63 10.5 2.4 6 7.3 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) KELK PF15796.5 EAX84318.1 - 2.1 8.9 6.9 3.8 8.0 1.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX84319.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX84320.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DDR PF08841.10 EAX84321.1 - 0.066 12.2 0.1 0.069 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX84321.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2939 PF11159.8 EAX84322.1 - 0.065 13.7 0.1 0.087 13.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX84323.1 - 0.0099 15.9 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX84328.1 - 9.6e-07 28.5 3.9 9.6e-07 28.5 3.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84328.1 - 2.7e-05 24.0 0.2 0.19 11.4 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84328.1 - 3.8e-05 24.0 0.2 0.00027 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84328.1 - 0.00017 21.7 3.8 0.00029 20.9 3.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84328.1 - 0.00064 19.5 0.1 0.0013 18.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX84328.1 - 0.0013 18.4 0.4 0.0091 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX84328.1 - 0.0026 17.6 1.3 0.0058 16.4 1.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX84328.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84328.1 - 0.062 12.9 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84328.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84328.1 - 0.11 12.9 0.1 0.77 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84328.1 - 0.8 10.0 5.4 11 6.4 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1827) CSG2 PF16965.5 EAX84329.1 - 0.032 13.2 0.0 0.032 13.2 0.0 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator LRR_5 PF13306.6 EAX84330.1 - 3.2e-34 117.7 12.1 2e-23 82.8 1.9 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84330.1 - 1.9e-08 33.9 3.8 0.0093 15.7 0.0 5.3 3 1 2 5 5 5 2 Leucine rich repeat RIFIN PF02009.16 EAX84330.1 - 0.00059 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 EAX84330.1 - 0.00069 19.5 1.7 0.0013 18.7 1.7 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 EAX84330.1 - 0.0027 18.0 2.6 0.0091 16.3 2.6 1.8 1 1 0 1 1 1 1 Orf78 (ac78) PRIMA1 PF16101.5 EAX84330.1 - 0.032 14.3 4.6 0.71 9.9 3.7 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4366 PF14283.6 EAX84330.1 - 0.036 14.1 1.7 0.065 13.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1180 PF06679.12 EAX84330.1 - 0.087 13.2 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Shisa PF13908.6 EAX84330.1 - 0.09 13.0 0.9 0.19 11.9 0.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Menin PF05053.13 EAX84330.1 - 0.17 10.2 1.5 0.24 9.7 1.5 1.1 1 0 0 1 1 1 0 Menin UL42 PF17638.2 EAX84330.1 - 0.83 9.6 7.8 3.6 7.6 2.5 2.4 2 0 0 2 2 2 0 HCMV UL42 Ldh_1_N PF00056.23 EAX84331.1 - 4.9e-28 98.0 0.0 7.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX84331.1 - 1.9e-21 76.7 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX84331.1 - 0.044 14.0 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons DUF3839 PF12943.7 EAX84332.1 - 3.2e-158 524.5 13.8 4.1e-158 524.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84332.1 - 0.051 13.9 0.6 3.6 7.9 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84332.1 - 1.6 9.2 5.4 2.3 8.8 0.3 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX84334.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX84335.1 - 4.4e-157 520.8 12.4 5.4e-157 520.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84335.1 - 0.81 10.2 4.5 4.5 7.8 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX84336.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAX84337.1 - 7.4e-25 87.7 6.5 1.4e-24 86.8 6.5 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX84337.1 - 0.018 15.1 2.4 1.2 9.2 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX84337.1 - 0.13 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain KilA-N PF04383.13 EAX84339.1 - 3.9e-23 81.4 0.4 5.3e-23 81.0 0.4 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX84339.1 - 0.031 14.2 0.0 0.085 12.8 0.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX84340.1 - 1.4e-155 515.9 11.6 1.7e-155 515.5 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84340.1 - 0.099 12.5 0.9 0.29 11.0 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84340.1 - 0.33 11.2 4.0 1.5 9.1 0.1 3.3 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84340.1 - 2 8.9 5.9 3.8 8.0 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84341.1 - 1.5e-41 140.7 0.5 3.9e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX84343.1 - 5.9e-06 26.8 0.2 1.5e-05 25.5 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX84343.1 - 0.024 14.2 0.4 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF2897 PF11446.8 EAX84344.1 - 0.9 9.5 3.3 1.7 8.6 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Ly49 PF08391.10 EAX84344.1 - 1.6 9.1 5.3 1.1 9.7 3.8 1.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF3839 PF12943.7 EAX84345.1 - 9.4e-156 516.4 14.1 1.2e-155 516.0 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84345.1 - 0.06 13.8 0.4 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX84345.1 - 0.14 12.7 5.5 0.18 12.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX84345.1 - 0.3 11.6 5.8 5.5 7.5 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX84346.1 - 1.4e-228 759.2 15.3 2.3e-228 758.4 15.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX84346.1 - 0.019 14.8 1.1 0.025 14.4 0.1 1.7 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) FapA PF03961.13 EAX84346.1 - 6.8 5.2 7.2 2.4 6.7 3.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A FTCD_C PF04961.12 EAX84346.1 - 9.2 6.0 6.9 24 4.6 0.1 2.8 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase Pox_D5 PF03288.16 EAX84347.1 - 5e-06 26.9 0.4 7e-06 26.5 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX84347.1 - 0.017 15.7 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX84347.1 - 0.041 13.9 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX84348.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX84349.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX84350.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84350.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84350.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84350.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84350.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84350.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84350.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84350.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84350.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84350.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84350.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84350.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84351.1 - 3.7e-17 62.2 2.1 3.9e-17 62.1 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84351.1 - 0.0036 17.9 0.0 0.008 16.8 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family DUF4107 PF13389.6 EAX84352.1 - 1.4e-71 239.9 3.5 2.4e-71 239.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84352.1 - 0.1 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF2960 PF11173.8 EAX84354.1 - 0.045 14.2 0.3 0.12 12.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) KilA-N PF04383.13 EAX84355.1 - 7.2e-11 41.9 0.2 1.4e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX84355.1 - 0.22 10.9 0.2 0.53 9.7 0.2 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX84356.1 - 2.2e-156 518.4 13.3 2.8e-156 518.1 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) EF-hand_10 PF14788.6 EAX84358.1 - 0.0031 17.4 0.1 0.0085 15.9 0.1 1.8 1 0 0 1 1 1 1 EF hand KilA-N PF04383.13 EAX84359.1 - 3.1e-41 139.7 0.2 3.1e-41 139.7 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX84359.1 - 0.018 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase DUF3213 PF11491.8 EAX84359.1 - 0.021 15.0 0.1 0.059 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX84359.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ResIII PF04851.15 EAX84360.1 - 3.7e-05 23.8 3.0 7.4e-05 22.8 2.9 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84360.1 - 0.00041 20.2 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX84360.1 - 0.00043 20.6 0.0 0.00072 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX84360.1 - 0.00096 19.0 0.1 0.0016 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX84360.1 - 0.0022 17.5 0.6 0.047 13.1 0.6 2.2 1 1 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 EAX84360.1 - 0.0086 16.4 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain RPA_interact_M PF14767.6 EAX84360.1 - 0.017 15.7 0.1 0.03 14.9 0.1 1.5 1 1 0 1 1 1 0 Replication protein A interacting middle DUF4588 PF15251.6 EAX84360.1 - 0.056 13.2 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX84360.1 - 0.077 12.7 0.5 0.14 11.8 0.2 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX84360.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX84360.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX84360.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX84360.1 - 0.54 10.7 2.8 0.41 11.1 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 EAX84361.1 - 1.1e-70 238.1 0.0 3e-70 236.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84361.1 - 7.7e-38 130.3 0.0 1.6e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX84361.1 - 1.3e-07 31.2 0.0 3.8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX84361.1 - 1.7e-05 23.8 0.0 3.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX84361.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX84361.1 - 0.0026 17.4 0.9 1.9 8.0 0.0 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX84361.1 - 0.013 15.5 0.0 0.044 13.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX84361.1 - 0.016 14.2 2.6 0.037 13.0 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EAX84361.1 - 0.046 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FeoB_Cyto PF17910.1 EAX84361.1 - 4.6 7.9 7.6 2 9.0 0.3 3.9 5 1 1 6 6 6 0 FeoB cytosolic helical domain Ras PF00071.22 EAX84362.1 - 6.4e-38 129.9 0.0 7.6e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX84362.1 - 8.1e-25 87.4 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX84362.1 - 7.3e-12 45.1 0.0 9.5e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX84362.1 - 1.4e-05 24.5 0.0 1.7e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX84362.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX84362.1 - 0.0029 17.6 0.1 1.1 9.1 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX84362.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX84362.1 - 0.0047 16.5 0.1 0.06 12.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAX84362.1 - 0.19 12.1 0.1 0.39 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DDR PF08841.10 EAX84364.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX84364.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FAS_N PF17828.1 EAX84366.1 - 0.0089 16.0 0.1 0.01 15.9 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX84367.1 - 6.3e-30 104.4 7.7 8.4e-30 104.0 7.7 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX84370.1 - 1.2e-140 466.9 9.6 1.4e-140 466.7 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX84370.1 - 0.2 12.1 2.3 4 8.0 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX84370.1 - 0.93 10.0 4.8 5.6 7.5 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX84372.1 - 5.5e-06 26.0 0.5 6.5e-06 25.8 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX84372.1 - 0.04 14.2 0.9 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 EAX84373.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84373.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84373.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84373.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84373.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84373.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84373.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84373.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84373.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84373.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84373.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84373.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) NMT PF01233.19 EAX84374.1 - 1.2 9.0 4.3 0.29 10.9 0.4 1.9 2 1 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4108 PF13390.6 EAX84375.1 - 1.4e-57 193.6 6.6 1.5e-57 193.5 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX84376.1 - 5e-06 26.9 0.4 7e-06 26.5 0.4 1.4 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX84376.1 - 0.017 15.7 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX84376.1 - 0.041 13.9 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Trypan_PARP PF05887.11 EAX84379.1 - 0.09 12.8 10.9 0.14 12.1 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.13 EAX84381.1 - 1.4e-43 147.2 0.8 3e-43 146.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84381.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF4106 PF13388.6 EAX84382.1 - 2.6e-274 909.8 21.8 2.6e-274 909.8 21.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3839 PF12943.7 EAX84384.1 - 6.5e-157 520.2 12.2 8.2e-157 519.9 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84384.1 - 0.082 13.4 3.7 2.2 8.8 0.1 3.4 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX84384.1 - 0.084 13.3 1.9 0.2 12.1 0.5 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX84384.1 - 0.12 12.7 1.4 17 5.8 0.1 3.6 3 1 1 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX84384.1 - 2.7 8.6 6.6 0.41 11.2 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX84385.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX84385.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX84386.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Drf_FH1 PF06346.12 EAX84387.1 - 4.6e-11 42.7 41.2 6e-06 26.1 16.4 3.4 1 1 2 3 3 3 3 Formin Homology Region 1 MgtE_N PF03448.17 EAX84387.1 - 0.14 12.7 8.9 6.9 7.3 0.2 4.8 2 1 4 6 6 6 0 MgtE intracellular N domain Pox_A32 PF04665.12 EAX84388.1 - 0.00011 21.8 2.9 0.00012 21.6 1.8 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX84388.1 - 0.0058 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX84388.1 - 0.027 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4795 PF16043.5 EAX84389.1 - 0.00093 18.8 13.9 0.08 12.5 1.2 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) IL17_R_N PF15037.6 EAX84389.1 - 0.0059 15.6 3.4 0.75 8.7 0.4 2.1 1 1 1 2 2 2 2 Interleukin-17 receptor extracellular region PH_3 PF14593.6 EAX84389.1 - 0.015 15.4 0.5 6.1 7.0 0.1 2.5 2 0 0 2 2 2 0 PH domain AlkA_N PF06029.11 EAX84389.1 - 0.032 14.5 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AlkA N-terminal domain EpuA PF11772.8 EAX84389.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF5348 PF17295.2 EAX84389.1 - 0.29 11.1 3.2 13 5.8 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5348) GPS2_interact PF15784.5 EAX84391.1 - 0.094 13.2 1.2 0.13 12.8 1.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain UPF0254 PF06787.11 EAX84391.1 - 0.16 11.7 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Trypan_PARP PF05887.11 EAX84392.1 - 0.15 12.0 11.9 0.24 11.4 11.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX84393.1 - 3.9e-11 42.9 0.2 4.6e-11 42.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX84395.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TNFR_16_TM PF18422.1 EAX84397.1 - 3.5 7.7 5.3 3.4 7.7 0.7 2.8 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Pox_A32 PF04665.12 EAX84399.1 - 3.3e-05 23.5 2.3 3.3e-05 23.5 2.3 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX84399.1 - 0.0041 17.1 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX84399.1 - 0.0096 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX84399.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX84399.1 - 0.068 13.4 2.1 0.15 12.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX84400.1 - 1.3e-135 450.4 10.6 1.5e-135 450.3 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84400.1 - 0.24 11.9 2.6 0.8 10.2 0.6 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84401.1 - 5.4e-156 517.2 13.6 7.1e-156 516.8 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84401.1 - 0.13 12.5 2.0 0.17 12.1 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function DUF29 KELK PF15796.5 EAX84401.1 - 0.13 12.7 4.6 2 8.9 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX84401.1 - 1.3 9.7 4.8 3.4 8.3 0.0 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF2408 PF10303.9 EAX84401.1 - 2.2 8.8 6.8 0.34 11.5 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX84403.1 - 2.2e-157 521.7 14.5 2.8e-157 521.4 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84403.1 - 0.03 14.2 1.1 0.1 12.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Fez1 PF06818.15 EAX84403.1 - 0.13 12.7 2.9 0.14 12.6 0.6 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84403.1 - 0.41 11.1 7.0 2.5 8.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84403.1 - 1.2 9.7 8.1 0.26 11.8 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX84404.1 - 1.5e-140 466.6 14.3 1.9e-140 466.3 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX84404.1 - 0.0021 18.6 1.1 0.01 16.3 0.2 2.6 3 0 0 3 3 3 1 T5orf172 domain DUF29 PF01724.16 EAX84404.1 - 0.0059 16.8 0.5 0.18 12.0 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF29 ArsA_ATPase PF02374.15 EAX84404.1 - 0.18 11.0 2.2 0.74 8.9 0.2 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase DUF3839 PF12943.7 EAX84405.1 - 7.4e-155 513.5 11.8 9.3e-155 513.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84405.1 - 0.12 12.9 1.4 0.3 11.5 0.2 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX84405.1 - 0.12 12.2 1.1 0.32 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84405.1 - 0.12 12.8 4.8 4.2 7.9 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DpnII PF04556.12 EAX84406.1 - 0.0086 15.4 1.1 0.0094 15.3 1.1 1.2 1 0 0 1 1 1 1 DpnII restriction endonuclease CpxA_peri PF16527.5 EAX84406.1 - 0.018 15.4 1.7 0.022 15.2 1.7 1.2 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain ERM PF00769.19 EAX84406.1 - 0.025 14.4 9.7 0.026 14.3 9.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2203 PF09969.9 EAX84406.1 - 0.046 14.4 3.2 0.048 14.4 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Carbpep_Y_N PF05388.11 EAX84406.1 - 0.048 14.2 0.9 0.059 13.9 0.9 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF720 PF05302.11 EAX84406.1 - 0.056 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF641 PF04859.12 EAX84406.1 - 0.086 13.2 9.3 0.044 14.1 7.7 1.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) pRN1_helical PF13010.6 EAX84406.1 - 0.42 10.6 6.3 0.55 10.2 6.3 1.2 1 0 0 1 1 1 0 Primase helical domain Borrelia_P83 PF05262.11 EAX84406.1 - 1.1 7.7 8.6 1.3 7.5 8.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.9 EAX84406.1 - 2.2 7.3 7.4 2.1 7.3 7.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gemini_AL1_M PF08283.11 EAX84407.1 - 0.014 15.4 0.2 0.037 14.1 0.2 1.8 1 0 0 1 1 1 0 Geminivirus rep protein central domain ABC_membrane PF00664.23 EAX84408.1 - 1.8e-43 149.2 19.6 2.2e-43 148.9 19.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX84408.1 - 1.2e-33 116.5 0.0 2.2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX84408.1 - 4.9e-08 32.7 0.0 3.2e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAX84408.1 - 0.00076 19.4 0.0 0.14 12.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAX84408.1 - 0.00088 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX84408.1 - 0.0019 18.5 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAX84408.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EAX84408.1 - 0.0029 18.0 0.3 0.0085 16.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAX84408.1 - 0.014 15.1 0.0 0.05 13.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAX84408.1 - 0.028 13.7 0.0 0.077 12.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 EAX84408.1 - 0.03 13.1 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 EAX84408.1 - 0.048 13.7 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EAX84408.1 - 0.048 12.8 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.15 EAX84408.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 EAX84408.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_membrane PF00664.23 EAX84409.1 - 4.7e-42 144.5 7.0 6.7e-42 144.0 7.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX84409.1 - 5.2e-36 124.2 1.6 5.4e-36 124.1 0.1 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAX84409.1 - 0.00019 21.0 1.9 0.00019 21.0 1.9 2.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAX84409.1 - 0.00032 21.1 0.5 0.001 19.5 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EAX84409.1 - 0.00046 19.5 0.1 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EAX84409.1 - 0.0025 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EAX84409.1 - 0.004 17.4 0.4 0.019 15.2 0.4 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAX84409.1 - 0.0079 16.1 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 EAX84409.1 - 0.015 15.0 0.1 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF3671 PF12420.8 EAX84409.1 - 0.37 10.9 1.6 2.3 8.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function Toprim_3 PF13362.6 EAX84409.1 - 0.43 11.0 1.6 3.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Toprim domain CDC45 PF02724.14 EAX84409.1 - 0.62 8.3 15.0 0.87 7.8 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane_3 PF12698.7 EAX84409.1 - 2.8 7.0 8.8 7.7 5.5 2.4 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein NPR3 PF03666.13 EAX84409.1 - 5.7 5.6 12.3 8.9 5.0 12.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 EAX84409.1 - 5.7 6.6 9.0 94 2.6 0.0 2.4 2 0 0 2 2 2 0 Connexin SID-1_RNA_chan PF13965.6 EAX84409.1 - 8 4.7 6.4 70 1.6 5.6 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ABC_tran PF00005.27 EAX84410.1 - 3.1e-34 118.4 0.0 4.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX84410.1 - 1.4e-08 34.4 0.3 1.1e-06 28.3 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAX84410.1 - 8.1e-05 22.6 0.0 0.042 13.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAX84410.1 - 0.0004 20.7 0.2 0.0019 18.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX84410.1 - 0.00043 20.7 0.1 0.0013 19.1 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EAX84410.1 - 0.00057 19.7 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX84410.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 EAX84410.1 - 0.0051 16.1 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.9 EAX84410.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 EAX84410.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EAX84410.1 - 0.025 14.6 0.1 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAX84410.1 - 0.03 14.1 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAX84410.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 EAX84410.1 - 0.033 13.3 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.25 EAX84410.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EAX84410.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain U71 PF17474.2 EAX84410.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Tegument protein UL11 homolog tRNA_lig_kinase PF08303.11 EAX84410.1 - 0.14 12.2 0.1 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_24 PF13479.6 EAX84410.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAX84410.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase KilA-N PF04383.13 EAX84411.1 - 6.3e-34 116.2 0.2 1.7e-33 114.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84411.1 - 0.0013 18.8 0.1 0.0039 17.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX84411.1 - 0.049 14.1 4.9 0.26 11.7 1.1 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4108 PF13390.6 EAX84414.1 - 2.3e-58 196.2 8.8 2.6e-58 196.0 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX84415.1 - 5.4e-40 135.7 0.6 1.1e-39 134.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84415.1 - 0.011 16.4 0.0 0.038 14.6 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family ABC1 PF03109.16 EAX84415.1 - 0.11 12.6 0.5 2.3 8.4 0.0 2.6 1 1 1 2 2 2 0 ABC1 family T5orf172 PF10544.9 EAX84416.1 - 1.1e-06 29.1 0.1 2.8e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84416.1 - 0.016 15.1 0.1 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX84416.1 - 0.075 12.6 0.5 0.2 11.2 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84417.1 - 4.6e-157 520.7 13.1 5.7e-157 520.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84417.1 - 0.17 12.3 4.7 2 8.9 0.1 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84419.1 - 4.3e-154 511.0 12.1 5.3e-154 510.7 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84419.1 - 0.12 12.9 1.2 0.47 10.9 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84419.1 - 0.14 12.6 3.7 4.9 7.7 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84419.1 - 1.1 9.8 5.1 0.62 10.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX84420.1 - 4.3e-39 132.8 0.6 8.9e-39 131.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX84421.1 - 1.1e-31 109.0 0.6 2.3e-31 107.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX84422.1 - 3.3e-05 24.4 0.1 8.6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84422.1 - 0.0026 17.6 0.3 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX84422.1 - 0.023 14.2 0.2 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Legume lectin domain DUF3447 PF11929.8 EAX84423.1 - 4e-40 135.6 6.4 4e-40 135.6 6.4 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX84423.1 - 4.8e-24 84.8 17.4 4.2e-13 49.7 1.6 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84423.1 - 1.6e-16 60.4 5.5 8.7e-08 32.6 0.0 5.2 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84423.1 - 1.5e-13 49.5 3.9 6.6e-06 26.1 0.0 6.2 5 1 2 7 7 7 2 Ankyrin repeat Ank PF00023.30 EAX84423.1 - 2.1e-12 46.9 0.4 9.3e-07 29.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX84423.1 - 3.1e-10 40.1 1.2 1.1e-07 32.0 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) RPAP2_Rtr1 PF04181.13 EAX84424.1 - 8.5e-05 22.8 4.2 0.00047 20.4 0.2 2.5 1 1 1 2 2 2 1 Rtr1/RPAP2 family DUF2116 PF09889.9 EAX84424.1 - 0.095 12.7 1.2 0.34 10.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Metallothio_Pro PF02069.16 EAX84424.1 - 0.12 12.6 1.0 0.21 11.8 1.0 1.3 1 0 0 1 1 1 0 Prokaryotic metallothionein RGI_lyase PF18370.1 EAX84425.1 - 3.3e-19 69.0 1.3 8.6e-19 67.6 0.3 2.3 2 0 0 2 2 2 1 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 EAX84425.1 - 0.00015 22.3 17.1 0.00016 22.2 3.2 4.3 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC2_membrane_3 PF12698.7 EAX84425.1 - 0.00049 19.3 0.4 0.00049 19.3 0.4 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein FG-GAP PF01839.23 EAX84425.1 - 0.0048 17.0 1.1 0.0048 17.0 1.1 3.3 3 0 0 3 3 3 1 FG-GAP repeat PQQ PF01011.21 EAX84425.1 - 0.013 15.4 0.1 0.17 11.8 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat PHZA_PHZB PF03284.13 EAX84425.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B DUF4366 PF14283.6 EAX84425.1 - 0.048 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TcdB_toxin_midN PF12256.8 EAX84425.1 - 0.056 12.8 0.2 6.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region TMEM154 PF15102.6 EAX84425.1 - 0.068 13.1 1.2 0.12 12.2 1.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 EAX84425.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Rifin FeoB_associated PF12669.7 EAX84425.1 - 0.15 12.5 0.9 0.26 11.7 0.9 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein OppC_N PF12911.7 EAX84425.1 - 0.37 10.8 1.5 0.78 9.8 1.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Insulin_TMD PF17870.1 EAX84425.1 - 0.93 9.6 3.2 1.5 8.9 0.8 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Flavodoxin_2 PF02525.17 EAX84426.1 - 7.6e-15 55.1 0.1 9.3e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold DDE_Tnp_4 PF13359.6 EAX84426.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease CREPT PF16566.5 EAX84428.1 - 0.023 14.9 0.3 0.053 13.7 0.3 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX84428.1 - 0.42 10.8 5.0 0.21 11.8 1.0 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3781 PF12636.7 EAX84429.1 - 0.032 14.1 1.0 0.055 13.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX84430.1 - 1.6e-71 239.7 4.4 2.1e-71 239.3 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84430.1 - 0.066 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX84432.1 - 0.0075 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase C2 PF00168.30 EAX84433.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 C2 domain B56 PF01603.20 EAX84437.1 - 1.1e-13 51.0 0.1 1.6e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF782 PF05614.11 EAX84437.1 - 0.055 13.9 0.4 5 7.6 0.1 2.4 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) DUF3839 PF12943.7 EAX84438.1 - 7.2e-80 267.9 9.3 9.8e-80 267.5 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX84438.1 - 0.02 14.9 0.4 6 6.9 0.2 2.3 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2408 PF10303.9 EAX84438.1 - 0.067 13.7 0.5 0.11 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX84439.1 - 3.3e-42 142.9 0.5 7.3e-42 141.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84439.1 - 0.0069 17.0 0.1 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX84440.1 - 1.6e-06 27.8 3.3 1.6e-06 27.8 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84440.1 - 2.5e-05 24.5 0.2 0.00018 21.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84440.1 - 4.7e-05 23.2 0.3 0.53 10.0 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84440.1 - 0.00013 22.0 3.2 0.00027 21.0 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84440.1 - 0.00048 20.0 0.1 0.00091 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84440.1 - 0.0014 18.4 0.5 0.0051 16.6 0.4 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84440.1 - 0.0015 18.2 0.4 0.011 15.3 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84440.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX84440.1 - 0.03 13.8 0.2 0.045 13.2 0.2 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX84440.1 - 0.051 13.1 0.0 0.17 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84440.1 - 0.071 13.5 0.1 0.61 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84440.1 - 0.081 12.4 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84440.1 - 0.49 10.7 4.4 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GST_C PF00043.25 EAX84443.1 - 0.013 15.7 1.5 4.5 7.6 0.0 3.2 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF4795 PF16043.5 EAX84443.1 - 0.049 13.2 9.0 3.6 7.1 0.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX84443.1 - 0.47 10.6 6.8 3.9 7.6 0.5 3.0 2 1 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) ESAG1 PF03238.13 EAX84443.1 - 1.6 8.1 5.4 7.5 5.9 0.2 3.3 2 1 1 4 4 4 0 ESAG protein Meiosis_expr PF15163.6 EAX84444.1 - 0.0086 16.7 1.3 0.011 16.4 0.5 1.6 2 0 0 2 2 2 1 Meiosis-expressed DUF365 PF04033.12 EAX84444.1 - 0.043 14.1 0.4 0.059 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Spo12 PF05032.12 EAX84444.1 - 0.82 9.6 10.0 0.17 11.8 2.9 2.9 4 0 0 4 4 4 0 Spo12 family DUF257 PF03192.13 EAX84445.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX84445.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Gly_rich PF12810.7 EAX84446.1 - 7.7e-22 78.4 46.9 9.3e-22 78.1 46.9 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX84447.1 - 1.4e-157 522.4 13.6 1.7e-157 522.1 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84447.1 - 0.15 12.5 2.9 0.13 12.7 0.6 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX84447.1 - 0.18 11.7 1.6 0.58 10.0 0.4 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84447.1 - 0.9 10.0 6.7 5.2 7.6 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84448.1 - 2e-17 63.1 0.1 4.4e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain DUF4795 PF16043.5 EAX84449.1 - 0.056 13.0 17.8 0.47 10.0 2.6 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX84449.1 - 0.096 12.8 9.6 0.048 13.7 2.2 3.9 3 1 0 3 3 3 0 Phage tail repeat like DUF2634 PF10934.8 EAX84449.1 - 0.22 11.7 4.6 5.4 7.2 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2634) Cag12 PF13117.6 EAX84449.1 - 2.1 8.9 6.7 0.62 10.6 0.6 3.1 2 1 0 3 3 3 0 Cag pathogenicity island protein Cag12 GPS2_interact PF15784.5 EAX84451.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84451.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX84452.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX84454.1 - 3.5e-13 49.4 27.3 4.6e-08 33.0 4.5 5.2 5 0 0 5 5 5 3 Phage tail repeat like WHEP-TRS PF00458.20 EAX84454.1 - 0.57 10.4 2.6 9.9 6.4 1.3 2.9 2 0 0 2 2 2 0 WHEP-TRS domain KilA-N PF04383.13 EAX84455.1 - 3.6e-40 136.3 2.9 7.1e-40 135.4 1.2 2.4 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84455.1 - 0.031 14.9 1.0 0.097 13.3 0.0 2.2 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX84456.1 - 1.7e-06 28.5 0.0 4.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84456.1 - 0.022 14.6 2.1 0.1 12.4 1.0 2.4 2 1 0 2 2 2 0 KilA-N domain DDR PF08841.10 EAX84457.1 - 0.11 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX84457.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX84458.1 - 0.14 12.1 12.0 0.23 11.4 12.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX84459.1 - 7.9e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX84459.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX84459.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX84459.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DNA_pol_B_2 PF03175.13 EAX84460.1 - 2.7e-10 39.7 3.1 1.3e-09 37.5 3.1 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX84461.1 - 4.8e-155 514.1 12.4 6.1e-155 513.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX84461.1 - 0.046 14.0 0.2 9.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Tup N-terminal NTP_transf_6 PF06042.11 EAX84461.1 - 0.13 12.1 0.7 0.35 10.7 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84461.1 - 0.14 12.4 1.0 7.8 6.8 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84461.1 - 1.6 9.2 4.7 5.1 7.6 0.1 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 EAX84462.1 - 5.2e-23 81.6 0.1 1.3e-21 77.0 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX84462.1 - 8.3e-23 81.1 0.1 1.4e-21 77.0 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAX84462.1 - 0.0038 17.2 0.1 0.0059 16.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family SelP_N PF04592.14 EAX84462.1 - 0.2 11.0 10.2 0.28 10.5 10.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Adeno_E3_CR2 PF02439.15 EAX84463.1 - 1.4e-05 24.8 7.1 2.8e-05 23.8 7.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 EAX84463.1 - 4.1e-05 23.5 0.4 7.7e-05 22.6 0.3 1.6 1 1 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 EAX84463.1 - 0.00027 20.4 0.0 0.00049 19.6 0.0 1.5 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Orf78 PF06024.12 EAX84463.1 - 0.00032 21.0 0.0 0.00089 19.5 0.0 1.7 2 0 0 2 2 1 1 Orf78 (ac78) DAG1 PF05454.11 EAX84463.1 - 0.00056 19.4 0.2 0.00074 19.0 0.2 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4690 PF15756.5 EAX84463.1 - 0.00071 20.1 0.2 0.0018 18.8 0.2 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage EphA2_TM PF14575.6 EAX84463.1 - 0.00072 20.4 0.0 0.0014 19.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EAX84463.1 - 0.0036 17.1 0.0 0.0055 16.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 EAX84463.1 - 0.0036 16.9 0.1 0.0091 15.6 0.1 1.5 1 1 0 1 1 1 1 CD34/Podocalyxin family ABC2_membrane_3 PF12698.7 EAX84463.1 - 0.0041 16.3 5.0 0.028 13.5 5.0 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein Stevor PF17410.2 EAX84463.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF5412 PF17428.2 EAX84463.1 - 0.011 15.6 1.4 6.6 6.6 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5412) Glycophorin_A PF01102.18 EAX84463.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF5305 PF17231.2 EAX84463.1 - 0.016 14.6 0.3 0.016 14.6 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) RIFIN PF02009.16 EAX84463.1 - 0.016 15.1 3.8 0.023 14.6 3.6 1.3 1 1 0 1 1 1 0 Rifin Podoplanin PF05808.11 EAX84463.1 - 0.019 15.1 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Podoplanin OAD_gamma PF04277.13 EAX84463.1 - 0.02 15.5 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ECSCR PF15820.5 EAX84463.1 - 0.028 14.2 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Tweety PF04906.13 EAX84463.1 - 0.03 13.0 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Tweety YajC PF02699.15 EAX84463.1 - 0.046 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 1 0 Preprotein translocase subunit Amnionless PF14828.6 EAX84463.1 - 0.05 12.4 0.0 0.076 11.8 0.0 1.3 1 1 0 1 1 1 0 Amnionless Shisa PF13908.6 EAX84463.1 - 0.06 13.6 0.2 0.091 13.0 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.11 EAX84463.1 - 0.077 13.2 0.7 0.18 12.1 0.3 1.8 2 0 0 2 2 1 0 Chordopoxvirus A13L protein DUF5385 PF17359.2 EAX84463.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RCR PF12273.8 EAX84463.1 - 0.14 12.8 0.1 0.38 11.4 0.1 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Asp4 PF16996.5 EAX84463.1 - 0.17 11.7 0.7 0.36 10.6 0.7 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 PTR PF12789.7 EAX84464.1 - 5.8e-39 132.0 29.9 2.1e-23 82.1 7.4 4.5 4 1 1 5 5 4 2 Phage tail repeat like DUF240 PF03086.14 EAX84464.1 - 0.083 12.8 6.6 1.7 8.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF240) DUF4116 PF13475.6 EAX84464.1 - 0.098 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GDP_Man_Dehyd PF16363.5 EAX84465.1 - 3.2e-69 233.9 0.0 3.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAX84465.1 - 6.2e-55 186.3 0.0 7.5e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAX84465.1 - 6.3e-25 87.9 0.0 3.9e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EAX84465.1 - 3.1e-19 69.1 0.1 4.1e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAX84465.1 - 2.8e-16 59.5 0.1 2.9e-11 43.0 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EAX84465.1 - 7.2e-10 38.4 0.0 1.1e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EAX84465.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAX84465.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family Ank_2 PF12796.7 EAX84468.1 - 9e-26 90.3 3.6 4.9e-11 43.1 0.5 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX84468.1 - 1.3e-23 80.5 3.4 0.00097 19.4 0.0 7.4 7 1 1 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 EAX84468.1 - 3.6e-22 78.4 2.8 2.9e-07 30.9 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX84468.1 - 8e-17 61.1 0.7 6.3e-06 26.4 0.4 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX84468.1 - 1.8e-13 50.3 1.6 0.019 15.4 0.0 5.9 7 0 0 7 7 7 4 Ankyrin repeat Aa_trans PF01490.18 EAX84470.1 - 6.5e-16 58.0 16.3 7.3e-16 57.9 16.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_B_2 PF03175.13 EAX84471.1 - 2.3e-11 43.3 1.9 1.1e-10 41.1 1.9 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX84471.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF3839 PF12943.7 EAX84474.1 - 9.3e-154 509.9 15.6 1.1e-153 509.6 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84474.1 - 0.065 13.7 1.5 0.23 11.9 0.3 2.1 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX84474.1 - 0.14 12.5 5.5 0.45 10.8 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84474.1 - 0.25 11.8 5.0 2.1 8.9 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX84474.1 - 0.29 11.0 1.8 0.72 9.7 0.3 2.0 1 1 0 2 2 2 0 Nucleotidyltransferase Ank_2 PF12796.7 EAX84475.1 - 1e-36 125.4 28.0 2.7e-15 56.7 4.7 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84475.1 - 8.5e-34 115.5 6.6 1.3e-09 38.4 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX84475.1 - 7.3e-20 70.5 3.3 0.014 15.8 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAX84475.1 - 1.1e-19 68.4 0.6 0.024 15.1 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX84475.1 - 1.5e-16 60.2 7.5 0.001 19.3 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) RL PF17797.1 EAX84475.1 - 0.00063 19.6 2.1 2.5 8.1 0.1 3.6 2 1 2 4 4 4 3 RL domain NADH-G_4Fe-4S_3 PF10588.9 EAX84475.1 - 0.00089 18.7 3.4 5.1 6.7 0.1 4.2 4 0 0 4 4 4 2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Shigella_OspC PF06128.11 EAX84475.1 - 0.0099 15.6 10.7 0.75 9.5 7.3 3.0 1 1 1 2 2 2 2 Shigella flexneri OspC protein Ribosomal_L30_N PF08079.12 EAX84475.1 - 0.02 15.1 12.0 0.13 12.6 0.3 3.4 1 1 2 3 3 3 0 Ribosomal L30 N-terminal domain DUF5064 PF16703.5 EAX84475.1 - 0.022 15.2 4.2 0.33 11.5 1.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5064) EZH2_WD-Binding PF11616.8 EAX84475.1 - 0.032 14.3 0.8 60 3.9 0.0 3.9 3 0 0 3 3 3 0 WD repeat binding protein EZH2 Glyco_hydro_92N PF17678.1 EAX84475.1 - 0.051 13.5 0.5 0.096 12.6 0.5 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain Ribosomal_S15 PF00312.22 EAX84475.1 - 0.25 11.6 7.7 27 5.1 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein S15 Stap_Strp_toxin PF01123.20 EAX84475.1 - 1.4 9.8 11.4 31 5.5 0.4 4.1 2 1 2 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain NAM-associated PF14303.6 EAX84475.1 - 4.1 8.1 17.8 24 5.6 6.4 3.1 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain DUF3447 PF11929.8 EAX84476.1 - 4.3e-15 55.4 4.7 4.3e-15 55.4 4.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX84476.1 - 0.00011 22.6 0.1 0.00089 19.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX84476.1 - 0.019 15.5 0.1 0.21 12.2 0.1 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX84477.1 - 1.4e-13 50.6 1.1 1.9e-13 50.2 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Alba PF01918.21 EAX84479.1 - 5.1e-13 48.6 0.9 6.6e-13 48.3 0.9 1.2 1 0 0 1 1 1 1 Alba DUF3839 PF12943.7 EAX84481.1 - 1.1e-157 522.7 14.2 1.5e-157 522.3 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84481.1 - 0.029 14.8 0.7 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Glu-tRNAGln PF02686.15 EAX84481.1 - 0.3 11.4 1.9 1.4 9.2 0.7 2.6 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX84481.1 - 2.2 8.8 9.0 2.4 8.7 1.2 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX84482.1 - 3e-57 192.6 5.0 3.3e-57 192.4 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX84483.1 - 1.1 9.2 4.2 2.2 8.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX84484.1 - 9.7e-07 28.5 2.0 9.7e-07 28.5 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84484.1 - 5e-05 23.6 0.2 0.0004 20.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84484.1 - 5.3e-05 23.0 0.4 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84484.1 - 0.00017 21.6 3.9 0.00041 20.4 4.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84484.1 - 0.00051 19.9 0.1 0.00095 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX84484.1 - 0.0012 18.5 0.7 0.014 15.0 0.7 2.2 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX84484.1 - 0.0017 18.2 0.9 0.0051 16.6 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX84484.1 - 0.014 15.8 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84484.1 - 0.073 12.6 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84484.1 - 0.08 12.4 0.1 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84484.1 - 0.086 13.3 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX84484.1 - 0.24 11.8 3.2 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX84484.1 - 0.39 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX84486.1 - 6.7e-55 186.2 5.6 9.1e-55 185.7 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX84486.1 - 0.087 13.4 0.4 0.11 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) GalP_UDP_transf PF01087.22 EAX84486.1 - 0.4 11.1 2.2 1 9.7 1.0 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX84487.1 - 1e-85 287.1 7.7 1.2e-85 286.9 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX84488.1 - 8.6e-62 207.3 8.6 9.5e-62 207.2 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_5 PF13306.6 EAX84493.1 - 8.2e-37 126.0 25.7 5.7e-20 71.6 6.7 4.0 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84493.1 - 2.8e-07 30.2 4.7 2.4 8.0 0.1 5.3 5 0 0 5 5 5 4 Leucine rich repeat DNA_pol_B_2 PF03175.13 EAX84495.1 - 2.3e-23 82.8 11.7 8.4e-23 81.0 11.7 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX84495.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Glycoprotein UL132 PTR PF12789.7 EAX84496.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.9 3 0 0 3 3 3 1 Phage tail repeat like Kinetochor_Ybp2 PF08568.10 EAX84496.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin PSP PF04046.16 EAX84497.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX84498.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX84500.1 - 2.3e-137 447.2 110.3 2.6e-31 107.5 21.4 6.9 2 2 6 8 8 7 5 Phage tail repeat like Apolipoprotein PF01442.18 EAX84500.1 - 6.9e-05 22.8 8.1 0.00086 19.2 5.7 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain RACo_linker PF17650.1 EAX84500.1 - 0.00035 20.4 4.8 0.99 9.3 0.1 4.9 2 1 5 7 7 7 1 RACo linker region PolyA_pol_arg_C PF12626.7 EAX84500.1 - 0.013 15.6 0.3 22 5.1 0.0 5.1 1 1 5 6 6 6 0 Polymerase A arginine-rich C-terminus HigB_toxin PF09907.9 EAX84500.1 - 0.014 15.6 4.5 38 4.6 0.1 4.7 2 1 4 6 6 6 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4116 PF13475.6 EAX84500.1 - 0.15 11.8 0.6 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX84500.1 - 0.19 12.1 23.9 11 6.5 0.3 8.3 1 1 8 9 9 9 0 TFIIH p62 subunit, N-terminal domain DUF2785 PF10978.8 EAX84500.1 - 1.6 8.5 16.1 0.92 9.3 3.5 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) Pox_A32 PF04665.12 EAX84501.1 - 1.2e-07 31.4 1.0 1.5e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84501.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Epimerase_2 PF02350.19 EAX84501.1 - 0.0066 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase IstB_IS21 PF01695.17 EAX84501.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84501.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF2805 PF10985.8 EAX84501.1 - 0.13 12.7 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) PTR PF12789.7 EAX84503.1 - 1.4e-48 162.7 29.4 2.3e-33 114.1 14.0 4.4 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX84503.1 - 0.088 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX84506.1 - 1e-65 220.9 12.6 5e-64 215.4 12.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX84510.1 - 1.5e-71 239.8 3.4 1.9e-71 239.4 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX84513.1 - 0.0094 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX84514.1 - 3.4e-156 517.8 13.1 4.2e-156 517.5 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84514.1 - 0.81 10.2 4.9 8.6 6.9 0.2 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84515.1 - 7.3e-128 425.1 7.8 8.2e-128 424.9 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX84518.1 - 3.8e-33 113.7 0.1 3.8e-33 113.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84518.1 - 0.0053 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Ycf34 PF10718.9 EAX84518.1 - 0.17 12.6 0.9 63 4.3 0.1 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3839 PF12943.7 EAX84519.1 - 8.5e-158 523.1 12.4 1.1e-157 522.8 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84519.1 - 0.11 12.9 0.2 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84519.1 - 0.21 12.0 3.6 2.1 8.9 0.4 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX84522.1 - 3.3e-07 30.0 2.3 4.8e-07 29.5 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84522.1 - 0.0032 17.2 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX84522.1 - 0.052 13.0 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX84522.1 - 0.056 13.2 0.2 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX84522.1 - 0.097 12.4 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX84522.1 - 0.42 10.8 8.5 5.5 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX84523.1 - 3e-41 139.8 1.8 3e-41 139.8 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84523.1 - 0.018 15.2 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX84523.1 - 0.025 13.8 0.1 0.074 12.3 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX84523.1 - 0.26 9.8 0.1 0.39 9.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX84525.1 - 3.1e-157 521.2 12.4 3.8e-157 520.9 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84525.1 - 0.083 13.3 1.6 0.4 11.1 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84525.1 - 0.24 11.9 6.9 2.4 8.7 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX84525.1 - 4.3 7.7 7.0 12 6.3 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal DUF3839 PF12943.7 EAX84526.1 - 1.7e-25 89.9 4.1 2.4e-25 89.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX84527.1 - 2.2e-32 111.2 0.5 5.5e-32 109.9 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX84528.1 - 1.6e-07 31.0 0.8 2e-07 30.7 0.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84528.1 - 0.0043 16.7 0.1 0.0063 16.2 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84528.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84528.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX84529.1 - 4.1e-52 177.0 3.5 4.5e-52 176.9 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4108 PF13390.6 EAX84530.1 - 2e-58 196.4 8.6 2.3e-58 196.2 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RGS12_us1 PF16613.5 EAX84531.1 - 0.32 11.3 3.4 0.52 10.6 3.4 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 ResIII PF04851.15 EAX84532.1 - 6.5e-05 23.0 0.1 8.3e-05 22.7 0.1 1.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX84532.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX84532.1 - 0.0019 18.5 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX84532.1 - 0.0025 17.6 0.0 0.0033 17.2 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX84532.1 - 0.0039 17.5 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX84532.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX84532.1 - 0.047 13.3 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX84532.1 - 0.086 12.6 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX84532.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2294 PF10057.9 EAX84534.1 - 0.00034 20.7 23.3 9.8 6.3 0.6 6.6 1 1 5 6 6 6 6 Uncharacterized conserved protein (DUF2294) DUF1935 PF09149.10 EAX84534.1 - 0.00093 19.6 23.9 0.51 10.7 2.9 3.8 1 1 2 3 3 3 3 Domain of unknown function (DUF1935) FAM219A PF15260.6 EAX84534.1 - 0.2 12.0 25.4 18 5.7 1.3 6.1 2 1 5 7 7 7 0 Protein family FAM219A FSAP_sig_propep PF03032.15 EAX84534.1 - 4.4 7.4 6.8 17 5.6 6.8 2.1 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide AlkA_N PF06029.11 EAX84534.1 - 5.1 7.4 10.3 47 4.3 1.1 3.7 1 1 3 4 4 4 0 AlkA N-terminal domain Fucose_iso_C PF02952.17 EAX84534.1 - 5.5 6.7 7.1 2.2 8.0 0.2 3.2 1 1 2 3 3 3 0 L-fucose isomerase, C-terminal domain DUF749 PF05370.11 EAX84534.1 - 6.4 6.9 19.9 19 5.4 0.6 5.2 2 1 5 7 7 7 0 Domain of unknown function (DUF749) Tail_tube PF10618.9 EAX84534.1 - 7.7 6.4 23.9 8.4 6.3 2.9 3.4 1 1 2 3 3 3 0 Phage tail tube protein GPS2_interact PF15784.5 EAX84536.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84536.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX84537.1 - 2.5e-156 518.3 12.1 3.1e-156 518.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84537.1 - 0.073 12.9 1.1 0.32 10.9 1.1 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84537.1 - 0.092 13.0 0.8 1.4 9.2 0.1 3.0 3 0 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84537.1 - 0.8 10.2 4.6 5.2 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84538.1 - 7.6e-22 77.3 3.2 1.2e-21 76.6 3.2 1.5 1 1 0 1 1 1 1 KilA-N domain GHBP PF12772.7 EAX84538.1 - 0.018 14.6 2.7 0.021 14.4 2.7 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Glyco_hydro_79n PF03662.14 EAX84538.1 - 0.072 12.0 0.1 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Imm70 PF15601.6 EAX84539.1 - 0.064 12.8 9.6 9.8 5.7 0.2 4.0 1 1 3 4 4 4 0 Immunity protein 70 DNA_pol_B_2 PF03175.13 EAX84540.1 - 3.2e-20 72.4 5.3 5.6e-20 71.6 5.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX84540.1 - 0.052 13.6 3.5 1.3 9.0 0.5 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5065) JMY PF15871.5 EAX84540.1 - 0.067 12.5 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF4107 PF13389.6 EAX84542.1 - 1.3e-67 227.0 2.7 1.7e-67 226.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX84543.1 - 4.9e-37 126.2 0.4 1.3e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84543.1 - 0.015 15.9 0.2 0.036 14.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX84544.1 - 1.9e-06 28.3 0.3 5e-06 27.0 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain FRG PF08867.11 EAX84544.1 - 0.01 16.7 0.1 0.59 11.1 0.0 2.2 2 0 0 2 2 2 0 FRG domain KilA-N PF04383.13 EAX84544.1 - 0.031 14.1 2.2 0.082 12.8 0.7 2.3 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX84545.1 - 7.6e-157 520.0 14.5 9.4e-157 519.7 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84545.1 - 1 9.9 7.8 2.3 8.8 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 EAX84546.1 - 1.1e-38 131.7 0.6 1.9e-10 41.2 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84546.1 - 1.1e-32 112.0 2.3 4.7e-10 39.8 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX84546.1 - 2.2e-27 94.8 0.3 3.5e-07 30.4 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84546.1 - 8.3e-26 87.2 0.6 5.9e-05 23.2 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EAX84546.1 - 4.5e-22 77.5 1.3 0.00026 21.3 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat DUF3447 PF11929.8 EAX84546.1 - 0.007 16.3 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX84546.1 - 0.061 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase Mito_fiss_reg PF05308.11 EAX84548.1 - 0.15 12.2 0.5 0.16 12.1 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3839 PF12943.7 EAX84549.1 - 2.4e-155 515.0 12.5 3e-155 514.7 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84549.1 - 0.041 14.3 2.2 0.098 13.1 0.4 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX84549.1 - 0.1 13.0 1.7 10 6.5 0.2 3.6 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX84549.1 - 0.35 11.4 4.4 5.2 7.6 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84549.1 - 0.85 10.2 6.1 0.37 11.4 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX84550.1 - 1.3e-72 243.3 4.1 1.5e-72 243.0 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2730 PF10805.8 EAX84553.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Ank_2 PF12796.7 EAX84554.1 - 2.8e-08 34.3 0.7 0.0036 17.9 0.0 4.8 3 2 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX84554.1 - 3.2e-08 33.2 1.1 0.17 12.5 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EAX84554.1 - 7.7e-08 32.7 0.2 0.28 11.8 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX84554.1 - 7.9e-06 26.0 0.1 0.0026 18.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX84554.1 - 0.0001 22.6 0.1 0.067 13.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 EAX84554.1 - 0.00023 21.1 0.1 0.00023 21.1 0.1 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) CDC37_C PF08564.10 EAX84554.1 - 0.0043 17.1 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Cdc37 C terminal domain DUF3896 PF13035.6 EAX84554.1 - 0.032 14.4 0.3 0.11 12.7 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) CSTF2_hinge PF14327.6 EAX84554.1 - 0.11 12.9 0.0 32 5.1 0.0 2.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 ubiquitin PF00240.23 EAX84555.1 - 0.0029 17.3 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX84555.1 - 0.099 12.5 0.1 0.37 10.6 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like KilA-N PF04383.13 EAX84556.1 - 6.4e-23 80.7 0.3 1.3e-22 79.7 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX84556.1 - 0.042 13.8 0.6 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX84556.1 - 0.3 10.5 0.7 1.3 8.3 0.3 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX84557.1 - 1.4e-156 519.1 13.4 1.7e-156 518.8 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84557.1 - 0.12 12.3 0.6 0.44 10.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX84557.1 - 0.2 11.9 1.1 0.5 10.7 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX84557.1 - 0.28 11.7 4.2 1.1 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2666 PF10869.8 EAX84558.1 - 0.028 14.6 1.2 0.07 13.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) PapD_N PF00345.20 EAX84560.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX84560.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX84560.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4107 PF13389.6 EAX84562.1 - 1.3e-72 243.3 4.1 1.7e-72 242.9 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84562.1 - 0.095 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX84563.1 - 0.0036 16.9 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX84564.1 - 7.4e-76 254.8 10.8 9.6e-76 254.4 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RIG-I_C PF18119.1 EAX84564.1 - 0.046 13.7 2.0 0.072 13.1 2.0 1.4 1 1 0 1 1 1 0 RIG-I receptor C-terminal domain DUF2408 PF10303.9 EAX84564.1 - 0.062 13.9 0.2 0.12 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) HSP70 PF00012.20 EAX84565.1 - 1.7e-57 195.0 1.6 1.9e-57 194.8 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX84565.1 - 1.7e-13 50.1 0.6 9.8e-13 47.6 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 EAX84565.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 StbA protein DDR PF08841.10 EAX84565.1 - 0.0012 17.9 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EAX84565.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Ppx-GppA PF02541.16 EAX84565.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Shisa PF13908.6 EAX84566.1 - 8.4e-09 35.9 5.8 9.6e-09 35.7 5.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.6 EAX84566.1 - 2.6e-06 28.0 0.2 3.3e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 FAM163 family RCR PF12273.8 EAX84566.1 - 7.9e-06 26.5 4.9 1.1e-05 26.0 4.9 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 EAX84566.1 - 0.00052 20.8 3.0 0.00092 20.0 3.0 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 EAX84566.1 - 0.00068 19.4 0.5 0.00077 19.2 0.5 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4083 PF13314.6 EAX84566.1 - 0.00092 19.1 0.4 0.0015 18.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) TMEM52 PF14979.6 EAX84566.1 - 0.0021 18.0 2.8 0.003 17.5 2.8 1.3 1 1 0 1 1 1 1 Transmembrane 52 Epiglycanin_C PF14654.6 EAX84566.1 - 0.0045 17.0 0.7 0.0072 16.4 0.7 1.3 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region DUF3328 PF11807.8 EAX84566.1 - 0.0063 16.3 0.2 0.0079 16.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4834 PF16118.5 EAX84566.1 - 0.012 16.6 0.6 0.022 15.7 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Podoplanin PF05808.11 EAX84566.1 - 0.022 14.9 3.1 0.022 14.9 3.1 1.4 1 1 0 1 1 1 0 Podoplanin Tmemb_185A PF10269.9 EAX84566.1 - 0.023 14.4 0.2 0.028 14.1 0.2 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein LRR19-TM PF15176.6 EAX84566.1 - 0.032 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Sigma_reg_N PF13800.6 EAX84566.1 - 0.034 14.4 0.0 0.051 13.9 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ECSCR PF15820.5 EAX84566.1 - 0.046 13.5 0.9 0.074 12.9 0.9 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Comm PF15957.5 EAX84566.1 - 0.057 13.8 2.5 0.094 13.1 2.5 1.4 1 1 0 1 1 1 0 Commissureless MFS_1 PF07690.16 EAX84566.1 - 0.059 12.3 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3139 PF11337.8 EAX84566.1 - 0.061 14.0 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) CD34_antigen PF06365.12 EAX84566.1 - 0.08 12.5 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family tRNA_anti-like PF12869.7 EAX84566.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like Baculo_F PF12259.8 EAX84566.1 - 0.1 11.1 0.2 0.12 10.9 0.2 1.0 1 0 0 1 1 1 0 Baculovirus F protein ODV-E18 PF10717.9 EAX84566.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Stevor PF17410.2 EAX84566.1 - 0.15 11.6 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF805 PF05656.14 EAX84566.1 - 0.19 12.2 0.1 0.27 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Adeno_E3_CR2 PF02439.15 EAX84566.1 - 0.38 10.5 13.7 0.68 9.7 13.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Claudin_2 PF13903.6 EAX84566.1 - 1.2 8.8 7.3 0.72 9.6 5.3 1.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TMEM154 PF15102.6 EAX84566.1 - 5.9 6.8 4.9 2.7 7.9 2.4 1.6 1 1 1 2 2 2 0 TMEM154 protein family DUF1179 PF06678.11 EAX84566.1 - 6.5 6.8 6.7 0.46 10.5 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) Pox_A32 PF04665.12 EAX84568.1 - 6e-06 25.9 3.2 8.8e-06 25.3 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84568.1 - 0.019 14.6 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX84568.1 - 0.095 12.5 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) LRR_5 PF13306.6 EAX84570.1 - 1.8e-86 286.5 56.6 1.8e-30 105.5 7.3 3.8 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84570.1 - 1.3e-12 47.2 5.4 0.0018 18.0 0.1 6.3 3 1 2 6 6 6 3 Leucine rich repeat TMEM154 PF15102.6 EAX84570.1 - 0.095 12.6 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 EAX84570.1 - 1.2 9.3 3.7 3 8.0 3.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DAG1 PF05454.11 EAX84570.1 - 3 7.2 7.3 0.97 8.8 3.1 2.2 3 0 0 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LRR_4 PF12799.7 EAX84570.1 - 3.5 8.2 15.5 19 5.9 0.8 5.6 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF5365 PF17326.2 EAX84571.1 - 0.012 16.0 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5365) MULE PF10551.9 EAX84572.1 - 0.079 13.4 0.5 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 MULE transposase domain Pox_A32 PF04665.12 EAX84574.1 - 6.1e-08 32.4 1.1 7.4e-08 32.1 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84574.1 - 0.0046 16.6 0.1 0.0071 16.0 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF3783 PF12646.7 EAX84574.1 - 0.021 14.8 0.5 0.62 10.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) IstB_IS21 PF01695.17 EAX84574.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein KilA-N PF04383.13 EAX84575.1 - 5.4e-19 68.1 1.0 1e-18 67.2 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84575.1 - 0.0083 16.7 0.1 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX84576.1 - 1.4e-153 509.2 12.6 1.8e-153 508.9 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2730 PF10805.8 EAX84576.1 - 0.062 13.4 1.2 8.6 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) KELK PF15796.5 EAX84576.1 - 0.49 10.9 4.2 3.9 8.0 0.2 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84577.1 - 1.6e-06 28.5 0.2 4.6e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX84577.1 - 0.014 14.9 0.4 0.33 10.4 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain F5_F8_type_C PF00754.25 EAX84578.1 - 0.00066 19.8 0.3 0.0017 18.4 0.3 1.6 2 0 0 2 2 2 1 F5/8 type C domain DUF641 PF04859.12 EAX84578.1 - 0.0024 18.2 0.5 0.0041 17.5 0.5 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) BTB PF00651.31 EAX84578.1 - 0.0063 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GrpE PF01025.19 EAX84578.1 - 0.029 14.0 0.3 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 EAX84578.1 - 0.048 13.4 1.5 0.088 12.6 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 EAX84578.1 - 0.055 14.1 0.2 0.099 13.3 0.2 1.4 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 EAX84578.1 - 0.071 13.2 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation RsfS PF02410.15 EAX84578.1 - 0.093 13.2 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation DUF1664 PF07889.12 EAX84578.1 - 0.1 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc29 PF17082.5 EAX84578.1 - 0.24 11.2 3.3 0.65 9.8 3.3 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 RGS PF00615.19 EAX84579.1 - 6.4e-07 29.7 0.8 2e-06 28.0 0.8 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2797 PF10977.8 EAX84579.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Pkinase PF00069.25 EAX84581.1 - 8.4e-56 189.3 0.0 1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84581.1 - 7.8e-32 110.6 0.0 1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX84581.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX84581.1 - 0.0071 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX84581.1 - 0.064 12.2 0.9 3.7 6.4 0.1 2.1 1 1 1 2 2 2 0 Haspin like kinase domain DNA_pol_B_2 PF03175.13 EAX84583.1 - 5.6e-09 35.4 1.0 1.2e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX84583.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX84583.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DNA_pol_B PF00136.21 EAX84583.1 - 0.16 10.6 1.6 1.9 7.1 1.5 2.2 1 1 0 1 1 1 0 DNA polymerase family B PapD_N PF00345.20 EAX84584.1 - 0.05 13.5 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX84585.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84585.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX84586.1 - 0.0053 16.8 0.2 0.007 16.4 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Spo12 PF05032.12 EAX84587.1 - 0.78 9.7 7.1 0.16 11.9 2.9 2.0 2 0 0 2 2 2 0 Spo12 family Tecti-min-caps PF09300.10 EAX84589.1 - 0.079 13.0 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Tectiviridae, minor capsid Pox_A32 PF04665.12 EAX84591.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84591.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84591.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84591.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84591.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84591.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84591.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84591.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84591.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84591.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84591.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84591.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX84592.1 - 0.25 11.2 2.2 0.51 10.3 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Trypan_PARP PF05887.11 EAX84593.1 - 0.063 13.3 11.3 0.099 12.6 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX84594.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84594.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX84596.1 - 1.2e-43 147.5 0.8 2.7e-43 146.4 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84596.1 - 0.021 15.0 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) TPR_MLP1_2 PF07926.12 EAX84597.1 - 0.0083 16.2 0.3 0.01 15.9 0.3 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX84597.1 - 0.081 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX84597.1 - 0.96 9.4 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family DUF4107 PF13389.6 EAX84600.1 - 5.1e-67 225.1 9.8 1.8e-66 223.3 9.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84600.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta GPS2_interact PF15784.5 EAX84602.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84602.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PSP PF04046.16 EAX84603.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX84604.1 - 7.4e-26 91.1 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX84604.1 - 0.073 13.2 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Associated with zinc fingers ZapB PF06005.12 EAX84604.1 - 0.16 12.4 0.9 0.69 10.4 0.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Pox_D5 PF03288.16 EAX84606.1 - 2.2e-05 24.8 2.3 0.00012 22.5 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX84606.1 - 0.059 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX84606.1 - 0.096 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain FAM153 PF15722.5 EAX84608.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 FAM153 family DUF3839 PF12943.7 EAX84609.1 - 1.9e-156 518.7 13.2 2.4e-156 518.4 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84609.1 - 0.084 12.7 1.3 0.35 10.7 1.3 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase PRD PF00874.20 EAX84609.1 - 0.62 10.4 4.5 0.7 10.2 0.1 3.0 3 1 0 3 3 3 0 PRD domain KELK PF15796.5 EAX84609.1 - 0.86 10.1 5.5 1.6 9.2 0.3 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84612.1 - 3.2e-155 514.7 12.6 3.6e-155 514.5 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84612.1 - 0.076 12.9 0.7 0.23 11.3 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84612.1 - 0.14 12.5 0.6 5.8 7.3 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84612.1 - 1.4 9.4 5.2 3.7 8.1 0.3 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5365 PF17326.2 EAX84614.1 - 0.029 14.8 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX84614.1 - 0.041 14.2 0.4 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 PWI domain KilA-N PF04383.13 EAX84615.1 - 0.0006 19.6 0.3 0.0016 18.3 0.2 1.7 1 1 1 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX84616.1 - 3.7e-32 110.5 0.4 9.2e-32 109.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX84617.1 - 4.6e-07 30.3 0.1 1e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84617.1 - 0.0088 15.9 0.5 0.073 12.9 0.1 2.3 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX84618.1 - 1.7e-156 518.8 14.9 2.2e-156 518.5 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84618.1 - 0.061 13.8 1.2 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX84618.1 - 0.18 11.7 1.5 0.47 10.3 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84618.1 - 3.4 8.2 7.6 4.1 7.9 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84619.1 - 7.1e-13 48.4 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX84619.1 - 0.12 11.8 0.8 0.15 11.5 0.8 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX84619.1 - 0.23 10.9 0.5 0.42 10.0 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Ribosomal_S26e PF01283.19 EAX84621.1 - 4.8e-46 155.6 7.3 5.4e-46 155.5 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Sgf11 PF08209.11 EAX84621.1 - 0.013 15.0 0.2 0.013 15.0 0.2 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 EAX84621.1 - 0.027 14.5 0.9 0.67 10.0 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon SRP19 PF01922.17 EAX84621.1 - 0.064 14.2 0.1 0.095 13.7 0.1 1.5 1 1 0 1 1 1 0 SRP19 protein OrfB_Zn_ribbon PF07282.11 EAX84621.1 - 0.49 10.4 6.0 7 6.7 0.5 2.2 1 1 0 2 2 2 0 Putative transposase DNA-binding domain LRR_5 PF13306.6 EAX84622.1 - 1.8e-62 209.0 24.8 7.9e-29 100.2 3.9 4.6 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84622.1 - 2e-10 40.3 2.8 0.0018 18.0 0.0 5.6 6 1 0 6 6 6 2 Leucine rich repeat MGC-24 PF05283.11 EAX84622.1 - 0.0038 17.7 2.0 0.0096 16.4 0.1 2.5 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_4 PF12799.7 EAX84622.1 - 0.012 16.0 7.8 2.8 8.5 0.0 5.5 7 2 1 8 8 8 0 Leucine Rich repeats (2 copies) RIC3 PF15361.6 EAX84622.1 - 0.053 13.9 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4366 PF14283.6 EAX84622.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Pox_A32 PF04665.12 EAX84623.1 - 6.3e-07 29.1 2.7 6.3e-07 29.1 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84623.1 - 3.2e-05 24.2 0.3 0.00022 21.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84623.1 - 8e-05 22.7 3.2 0.00018 21.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX84623.1 - 0.00016 21.5 0.3 0.42 10.3 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX84623.1 - 0.00021 21.1 0.1 0.00037 20.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84623.1 - 0.0011 18.9 0.8 0.0019 18.1 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84623.1 - 0.002 17.8 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84623.1 - 0.0096 16.3 0.0 0.019 15.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX84623.1 - 0.068 12.7 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX84623.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84623.1 - 0.087 13.3 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2947 PF11163.8 EAX84624.1 - 0.059 13.2 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) KilA-N PF04383.13 EAX84625.1 - 2.2e-40 137.0 1.5 2.9e-40 136.6 0.3 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84625.1 - 0.007 16.5 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX84625.1 - 0.12 10.9 0.2 0.18 10.3 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX84626.1 - 3.4e-158 524.4 13.5 4.3e-158 524.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84626.1 - 3 8.4 6.0 5.1 7.6 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84627.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Ras PF00071.22 EAX84628.1 - 7e-53 178.5 0.3 8.1e-53 178.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX84628.1 - 4.9e-30 104.2 0.0 9.3e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX84628.1 - 6.3e-12 45.3 0.1 8.1e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX84628.1 - 2.1e-05 24.0 0.2 2.7e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX84628.1 - 7.7e-05 22.7 0.1 0.11 12.5 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX84628.1 - 0.00049 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EAX84628.1 - 0.0019 18.2 0.0 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.17 EAX84628.1 - 0.0027 17.5 0.2 0.47 10.2 0.2 2.2 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EAX84628.1 - 0.01 15.8 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EAX84628.1 - 0.024 14.1 0.0 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit YTH PF04146.15 EAX84628.1 - 0.058 13.3 0.2 0.11 12.5 0.2 1.4 1 1 0 1 1 1 0 YT521-B-like domain AAA_16 PF13191.6 EAX84628.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MAP65_ASE1 PF03999.12 EAX84630.1 - 8.3e-25 87.5 17.7 2.2e-24 86.2 17.4 1.6 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) BCDHK_Adom3 PF10436.9 EAX84630.1 - 0.02 14.8 1.7 0.031 14.1 0.1 2.1 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF760 PF05542.11 EAX84630.1 - 0.087 13.2 0.0 0.36 11.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF760) BAR PF03114.18 EAX84630.1 - 1.2 8.8 16.8 6.2 6.4 3.1 3.8 2 2 1 3 3 3 0 BAR domain Adaptin_binding PF10199.9 EAX84630.1 - 1.4 9.5 8.8 8.2 7.1 3.2 3.1 2 2 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 P4Ha_N PF08336.11 EAX84630.1 - 3.9 7.5 18.2 1.5 8.9 3.2 3.9 2 2 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Apolipoprotein PF01442.18 EAX84630.1 - 3.9 7.3 14.5 2.5 8.0 0.1 3.3 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain Peptidase_C2 PF00648.21 EAX84631.1 - 1.4e-24 86.7 0.0 2.1e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Caldesmon PF02029.15 EAX84631.1 - 0.049 12.4 44.1 0.067 11.9 44.1 1.1 1 0 0 1 1 1 0 Caldesmon Paf1 PF03985.13 EAX84631.1 - 1.4 7.9 33.9 2.2 7.2 33.9 1.3 1 0 0 1 1 1 0 Paf1 DDHD PF02862.17 EAX84631.1 - 4 7.5 6.2 9.1 6.4 6.2 1.7 1 0 0 1 1 1 0 DDHD domain PSP PF04046.16 EAX84632.1 - 0.065 13.1 0.8 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4795 PF16043.5 EAX84633.1 - 0.23 11.0 18.0 0.19 11.3 5.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) TetR_C_26 PF17934.1 EAX84633.1 - 2.3 8.6 10.5 1.4 9.3 0.6 3.2 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2018 PF09442.10 EAX84633.1 - 2.3 9.2 7.6 0.42 11.6 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF3839 PF12943.7 EAX84634.1 - 1.7e-157 522.1 12.8 2.1e-157 521.8 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84634.1 - 0.13 12.1 0.7 0.43 10.4 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX84634.1 - 1.1 9.8 4.3 1.3 9.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX84634.1 - 3.3 8.2 7.3 2.6 8.6 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84635.1 - 2.8e-41 139.9 0.5 7.4e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_D5 PF03288.16 EAX84636.1 - 0.00014 22.3 3.8 0.0011 19.4 3.8 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX84636.1 - 0.092 12.7 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX84638.1 - 6.6e-31 106.5 0.3 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX84639.1 - 6.5e-26 91.3 4.5 9.5e-26 90.7 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84640.1 - 6.8e-154 510.3 12.6 8.5e-154 510.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84640.1 - 0.03 14.6 0.6 2.5 8.5 0.0 3.4 3 1 1 4 4 4 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX84640.1 - 0.072 13.0 0.5 0.23 11.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84640.1 - 0.54 10.7 4.6 4.3 7.9 0.4 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84641.1 - 1.1e-05 25.8 0.1 2.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84642.1 - 1.2e-33 115.3 0.7 2.1e-33 114.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84642.1 - 0.028 15.0 0.1 0.074 13.7 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX84643.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84643.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84643.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84643.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84643.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84643.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84643.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84643.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84643.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84643.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84643.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84643.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TQ PF18202.1 EAX84644.1 - 3.6e-06 27.5 15.9 0.0069 16.9 4.7 2.3 1 1 1 2 2 2 2 T-Q ester bond containing domain DUF3474 PF11960.8 EAX84644.1 - 0.0019 18.4 0.8 0.98 9.6 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3474) CBX7_C PF17218.3 EAX84644.1 - 0.0036 17.0 4.1 1.3 8.8 0.3 2.6 2 0 0 2 2 2 2 CBX family C-terminal motif Tyr-DNA_phospho PF06087.12 EAX84644.1 - 0.0081 15.1 2.1 1.1 8.0 0.1 2.1 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase PQQ PF01011.21 EAX84644.1 - 0.046 13.7 0.9 11 6.2 0.1 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat PhoD_N PF16655.5 EAX84644.1 - 0.046 14.3 2.6 5.9 7.5 0.8 2.6 1 1 1 2 2 2 0 PhoD-like phosphatase, N-terminal domain Imm26 PF15428.6 EAX84644.1 - 0.069 13.4 1.2 11 6.3 0.0 2.5 2 1 0 2 2 2 0 Immunity protein 26 UL41A PF17591.2 EAX84644.1 - 0.11 12.6 0.1 28 4.9 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus UL41A Chordopox_G3 PF06129.12 EAX84644.1 - 0.13 13.0 2.3 12 6.7 0.2 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein PapD_N PF00345.20 EAX84644.1 - 0.89 9.5 7.6 6.3 6.7 1.1 2.5 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain IPU_b_solenoid PF18783.1 EAX84644.1 - 8.5 6.5 6.8 36 4.5 0.7 2.6 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat DUF3839 PF12943.7 EAX84645.1 - 1.4e-148 492.9 10.5 1.7e-148 492.6 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX84645.1 - 0.1 12.1 3.2 0.081 12.4 1.2 1.8 1 1 1 2 2 2 0 Z1 domain KELK PF15796.5 EAX84645.1 - 5.3 7.6 7.8 1.6 9.3 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HNH_3 PF13392.6 EAX84646.1 - 3.8e-06 26.6 0.5 6.8e-06 25.7 0.5 1.4 1 0 0 1 1 1 1 HNH endonuclease T2SSS_2 PF16549.5 EAX84646.1 - 0.023 14.7 1.1 0.041 13.9 0.5 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS) pilotin, S protein Selenoprotein_S PF06936.11 EAX84646.1 - 0.14 12.0 7.3 0.23 11.3 7.3 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Peroxin-13_N PF04088.13 EAX84646.1 - 4 7.7 9.0 1.2 9.4 4.3 2.3 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Pox_A32 PF04665.12 EAX84649.1 - 4.2e-07 29.7 0.1 1.2e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX84651.1 - 8.2e-79 264.5 11.0 1.1e-78 264.1 11.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX84652.1 - 2.2e-06 28.2 0.1 0.021 15.4 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX84652.1 - 0.0011 18.9 2.2 0.0011 18.9 2.2 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX84652.1 - 0.0017 18.7 0.1 7.5 7.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX84652.1 - 0.0032 18.0 0.4 7 7.4 0.0 3.6 4 2 0 4 4 4 2 Ankyrin repeats (many copies) CUE PF02845.16 EAX84652.1 - 0.086 12.6 0.1 5.1 6.9 0.0 2.7 3 0 0 3 3 3 0 CUE domain KRTAP7 PF15034.6 EAX84652.1 - 0.12 13.4 0.1 0.35 11.8 0.0 1.8 2 0 0 2 2 2 0 KRTAP type 7 family Ank PF00023.30 EAX84652.1 - 0.3 11.6 2.1 18 6.0 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat DUF4108 PF13390.6 EAX84653.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4108 PF13390.6 EAX84655.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Trypan_PARP PF05887.11 EAX84656.1 - 0.026 14.5 7.8 0.034 14.1 7.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_A32 PF04665.12 EAX84659.1 - 3.9e-07 29.8 0.0 5.3e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX84661.1 - 1.9e-145 482.6 15.9 2.3e-145 482.4 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84661.1 - 0.24 11.2 1.8 1.4 8.8 1.8 2.1 1 1 0 1 1 1 0 Nucleotidyltransferase PRD PF00874.20 EAX84661.1 - 0.82 10.0 0.1 0.82 10.0 0.1 3.4 4 1 1 5 5 5 0 PRD domain KELK PF15796.5 EAX84661.1 - 3.8 8.0 8.4 1.6 9.2 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84662.1 - 3.5e-156 517.8 13.5 4.3e-156 517.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX84663.1 - 1e-06 29.2 0.7 2.3e-06 28.1 0.2 1.8 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX84663.1 - 0.073 12.9 0.1 0.59 10.0 0.0 2.4 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX84664.1 - 1.9e-44 150.1 1.4 2.4e-44 149.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain RRP36 PF06102.12 EAX84664.1 - 0.64 10.0 10.4 0.12 12.4 6.7 1.6 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4106 PF13388.6 EAX84665.1 - 4.9e-264 875.9 63.0 5.8e-134 447.5 22.8 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF4106) DDR PF08841.10 EAX84666.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_5 PF13857.6 EAX84670.1 - 0.01 16.2 0.0 0.032 14.6 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CENP-R PF06729.12 EAX84670.1 - 3.4 7.6 12.4 8.4 6.3 7.3 2.4 1 1 1 2 2 2 0 Kinetochore component, CENP-R RasGAP PF00616.19 EAX84672.1 - 1.2e-10 41.5 0.0 2.5e-08 33.9 0.1 2.9 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase BssB_TutG PF18512.1 EAX84673.1 - 0.058 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Benzylsuccinate synthase beta subunit DUF3644 PF12358.8 EAX84674.1 - 1.7e-07 31.6 0.3 1.4 9.5 0.0 3.9 1 1 3 4 4 4 3 Protein of unknown function (DUF3644) DUF1930 PF09122.10 EAX84674.1 - 4.1e-05 23.5 8.9 1.4 9.0 0.1 6.3 1 1 6 7 7 7 1 Domain of unknown function (DUF1930) SNAD3 PF18749.1 EAX84674.1 - 8.4e-05 21.9 0.0 0.17 11.0 0.0 2.7 1 1 2 3 3 3 2 Secreted Novel AID/APOBEC-like Deaminase 3 Trigger_C PF05698.14 EAX84674.1 - 0.0015 18.6 0.0 0.66 10.0 0.0 2.1 1 1 1 2 2 2 2 Bacterial trigger factor protein (TF) C-terminus PTSIIA_gutA PF03829.13 EAX84674.1 - 0.0037 17.1 0.0 0.41 10.5 0.0 2.7 1 1 2 3 3 3 2 PTS system glucitol/sorbitol-specific IIA component UvrB PF12344.8 EAX84674.1 - 0.0041 16.9 0.1 55 3.7 0.0 4.2 3 0 0 3 3 3 0 Ultra-violet resistance protein B Speriolin_N PF15058.6 EAX84674.1 - 0.01 16.0 0.2 1.4 9.0 0.0 2.0 1 1 1 2 2 2 0 Speriolin N terminus FlgH PF02107.16 EAX84674.1 - 0.017 14.8 0.4 1.2 8.7 0.4 2.7 1 1 0 1 1 1 0 Flagellar L-ring protein AphA_like PF14557.6 EAX84674.1 - 0.059 13.1 1.2 0.77 9.5 0.3 2.0 1 1 1 2 2 2 0 Putative AphA-like transcriptional regulator Ery_res_leader2 PF08057.11 EAX84674.1 - 0.11 13.0 5.8 73 4.4 0.1 4.0 3 0 0 3 3 3 0 Erythromycin resistance leader peptide Cyclin_N PF00134.23 EAX84675.1 - 2.1e-17 63.0 0.0 5.2e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAX84675.1 - 1.1e-12 48.0 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain FAR1 PF03101.15 EAX84676.1 - 0.0069 17.1 0.3 0.013 16.2 0.3 1.5 1 1 0 1 1 1 1 FAR1 DNA-binding domain MULE PF10551.9 EAX84677.1 - 5.5e-10 39.5 0.2 9.8e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF1196 PF06709.11 EAX84677.1 - 0.34 11.1 2.4 1.2 9.3 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1196) HEAT PF02985.22 EAX84678.1 - 3.1e-05 23.9 0.1 0.004 17.3 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 EAX84678.1 - 0.00064 19.4 1.1 0.018 14.6 0.0 3.4 3 2 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 EAX84678.1 - 0.003 17.6 4.7 0.12 12.4 0.1 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EAX84678.1 - 0.0039 16.9 2.8 2.8 7.6 0.0 5.1 5 1 0 5 5 5 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EAX84678.1 - 0.0064 16.9 0.0 0.11 12.9 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats TIP120 PF08623.10 EAX84678.1 - 0.0092 15.8 0.2 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) FANCI_S2 PF14676.6 EAX84678.1 - 0.012 15.9 1.6 1.8 8.9 1.4 3.5 2 1 0 2 2 2 0 FANCI solenoid 2 SPG48 PF14764.6 EAX84678.1 - 0.028 14.9 2.2 0.23 11.9 0.2 3.6 3 1 1 4 4 4 0 AP-5 complex subunit, vesicle trafficking Adaptin_N PF01602.20 EAX84678.1 - 0.044 12.3 16.8 3 6.3 0.0 4.3 3 2 0 3 3 3 0 Adaptin N terminal region CBP4 PF07960.11 EAX84678.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 CBP4 HEAT_EZ PF13513.6 EAX84678.1 - 0.1 13.1 0.0 0.78 10.3 0.0 2.7 1 0 0 1 1 1 0 HEAT-like repeat alpha-hel2 PF14456.6 EAX84678.1 - 1.7 7.8 4.9 2 7.6 0.0 2.9 3 0 0 3 3 3 0 Alpha-helical domain 2 XPC-binding PF09280.11 EAX84678.1 - 2.1 8.1 7.4 1.5 8.6 0.2 3.4 3 0 0 3 3 3 0 XPC-binding domain RTP1_C1 PF10363.9 EAX84678.1 - 3.5 7.9 6.1 17 5.6 0.7 4.3 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4107 PF13389.6 EAX84680.1 - 1.3e-70 236.7 3.7 1.8e-70 236.3 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84680.1 - 0.065 13.6 0.7 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX84681.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX84682.1 - 9.5e-07 29.3 0.2 2.4e-06 28.0 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX84683.1 - 6.4e-16 58.5 3.2 9.2e-16 58.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX84684.1 - 5e-37 126.4 15.8 5.7e-18 65.3 0.1 5.4 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX84684.1 - 4.8e-27 91.0 6.5 1.4e-05 25.0 0.0 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX84684.1 - 1.6e-26 92.0 8.0 2.1e-08 34.3 0.0 7.8 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX84684.1 - 1.4e-25 89.3 11.7 1.1e-06 29.1 0.1 7.2 4 3 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX84684.1 - 7.9e-25 86.2 2.5 8.7e-05 22.8 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX84684.1 - 5.9e-15 55.0 8.2 5.9e-15 55.0 8.2 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Pkinase PF00069.25 EAX84685.1 - 3.2e-46 157.8 0.1 4.6e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84685.1 - 1.7e-17 63.6 0.0 2.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX84685.1 - 0.00036 19.9 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX84685.1 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX84685.1 - 0.002 17.3 0.1 0.0034 16.5 0.1 1.5 1 1 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EAX84685.1 - 0.006 15.9 0.0 0.065 12.5 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Choline_kinase PF01633.20 EAX84685.1 - 0.0064 16.1 0.1 0.017 14.7 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase T5orf172 PF10544.9 EAX84686.1 - 7.7e-07 29.6 0.2 2e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX84686.1 - 0.05 13.1 0.4 0.68 9.4 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX84686.1 - 0.059 13.2 0.1 0.34 10.8 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX84687.1 - 1.5e-33 114.9 0.6 3.3e-33 113.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX84688.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84688.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84688.1 - 4.1e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84688.1 - 0.00014 21.9 3.4 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84688.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84688.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84688.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84688.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84688.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84688.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84688.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84688.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX84689.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX84689.1 - 8.2 6.4 6.5 17 5.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX84690.1 - 9.6e-65 216.9 6.9 1.1e-64 216.7 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX84690.1 - 0.12 12.6 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX84691.1 - 1.5e-05 25.3 2.5 8.4e-05 23.0 2.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX84691.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) YpsA PF06908.11 EAX84691.1 - 0.04 13.9 0.7 0.084 12.9 0.2 1.7 2 0 0 2 2 2 0 YspA SLOG family RFX_DNA_binding PF02257.15 EAX84691.1 - 0.054 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3839 PF12943.7 EAX84692.1 - 8e-156 516.6 13.2 9.6e-156 516.4 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84692.1 - 0.58 10.6 8.2 0.79 10.2 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84694.1 - 1.8e-156 518.8 13.5 2.2e-156 518.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84694.1 - 0.77 10.3 5.1 2.1 8.9 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1947 PF09183.10 EAX84695.1 - 0.016 15.5 0.2 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) EpuA PF11772.8 EAX84695.1 - 0.027 14.2 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Gly-zipper_Omp PF13488.6 EAX84696.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX84696.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX84696.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif FGGY_N PF00370.21 EAX84697.1 - 1.3e-76 257.4 0.1 1.9e-76 256.9 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EAX84697.1 - 2.2e-53 180.9 0.1 4.3e-53 180.0 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pox_D5 PF03288.16 EAX84698.1 - 7.1e-05 23.2 2.8 0.00039 20.9 2.8 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX84698.1 - 0.015 14.4 1.0 0.021 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX84698.1 - 0.091 13.4 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX84699.1 - 2.6e-50 170.1 5.4 2.9e-50 169.9 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX84701.1 - 3.4e-33 113.8 0.9 8.1e-33 112.6 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX84702.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84702.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84702.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84702.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Tetraspanin PF00335.20 EAX84703.1 - 2.1e-20 73.4 19.6 2.8e-20 73.0 19.6 1.1 1 0 0 1 1 1 1 Tetraspanin family YfhO PF09586.10 EAX84703.1 - 0.021 13.1 1.6 0.032 12.5 1.6 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1772 PF08592.11 EAX84703.1 - 0.043 14.1 3.4 0.089 13.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 EAX84703.1 - 0.058 13.4 23.8 0.35 10.9 9.3 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 EAX84703.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.8 3 1 1 4 4 4 0 HemY protein N-terminus 7tm_6 PF02949.20 EAX84703.1 - 1 8.4 10.2 2 7.4 10.2 1.4 1 0 0 1 1 1 0 7tm Odorant receptor Jagunal PF07086.12 EAX84703.1 - 1.3 9.1 12.9 0.35 10.9 7.2 2.3 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF420 PF04238.12 EAX84703.1 - 5.5 7.3 15.7 0.86 9.9 10.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF420) TctB PF07331.11 EAX84703.1 - 6.1 7.1 21.1 3.8 7.8 14.8 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family CooT PF10133.9 EAX84704.1 - 0.06 13.6 0.4 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT PRA-PH PF01503.17 EAX84705.1 - 0.3 11.6 3.1 4.1 7.9 4.2 2.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Ax_dynein_light PF10211.9 EAX84707.1 - 2.4e-71 239.6 9.5 2.4e-71 239.6 9.5 1.6 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4055 PF13264.6 EAX84707.1 - 0.0044 17.2 2.1 0.0094 16.1 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) Filament PF00038.21 EAX84707.1 - 0.0055 16.3 2.8 0.0055 16.3 2.8 2.5 2 1 0 3 3 3 1 Intermediate filament protein TSNAXIP1_N PF15739.5 EAX84707.1 - 0.0081 16.5 2.8 0.0081 16.5 2.8 2.6 2 1 1 3 3 3 2 Translin-associated factor X-interacting N-terminus JIP_LZII PF16471.5 EAX84707.1 - 0.03 14.5 4.2 0.03 14.5 4.2 2.6 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 EAX84707.1 - 0.12 12.6 4.8 0.35 11.1 1.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMPIT PF07851.13 EAX84707.1 - 0.58 9.4 5.5 1.1 8.4 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein TMCO5 PF14992.6 EAX84707.1 - 1.2 8.6 15.2 0.31 10.6 8.4 2.4 1 1 1 2 2 2 0 TMCO5 family DUF5320 PF17253.2 EAX84707.1 - 1.8 9.7 5.1 2.7 9.1 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF724 PF05266.14 EAX84707.1 - 2.2 8.1 16.8 0.14 11.9 9.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 EAX84707.1 - 2.4 7.4 14.6 4.8 6.5 14.6 1.7 1 1 0 1 1 1 0 FAM76 protein Mod_r PF07200.13 EAX84707.1 - 2.9 8.0 16.4 0.32 11.1 7.9 2.9 2 2 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Uso1_p115_C PF04871.13 EAX84707.1 - 5.3 7.4 21.1 0.16 12.4 10.9 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 EAX84707.1 - 6.1 7.5 10.6 0.76 10.4 5.7 2.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.15 EAX84707.1 - 6.6 6.6 24.3 0.037 13.8 7.8 4.1 3 1 1 4 4 4 0 Septum formation initiator Pox_A32 PF04665.12 EAX84710.1 - 1.1e-06 28.3 3.3 1.1e-06 28.3 3.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84710.1 - 3.8e-05 23.5 0.3 0.41 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84710.1 - 7.7e-05 23.0 0.2 0.00053 20.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84710.1 - 0.00012 22.1 3.6 0.00026 21.0 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84710.1 - 0.00054 19.8 0.1 0.00097 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84710.1 - 0.002 18.0 0.9 0.0037 17.1 0.9 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84710.1 - 0.0023 17.6 0.5 0.013 15.1 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84710.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX84710.1 - 0.059 12.9 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX84710.1 - 0.081 12.5 0.0 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX84710.1 - 0.082 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX84710.1 - 0.086 12.3 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84710.1 - 0.13 12.7 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84710.1 - 0.38 11.0 4.1 9 6.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX84712.1 - 1.8e-114 373.8 84.7 8.3e-32 109.0 14.4 6.3 2 1 4 6 6 6 5 Phage tail repeat like Tis11B_N PF04553.12 EAX84712.1 - 0.041 14.4 2.8 4.3 7.9 0.3 2.7 1 1 1 2 2 2 0 Tis11B like protein, N terminus Apolipoprotein PF01442.18 EAX84712.1 - 0.063 13.1 4.3 1.4 8.7 1.1 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2785 PF10978.8 EAX84712.1 - 0.29 10.9 10.1 5.1 6.8 0.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) AviRa PF11599.8 EAX84712.1 - 0.43 10.0 9.1 0.51 9.8 0.6 3.0 1 1 2 3 3 3 0 RRNA methyltransferase AviRa DUF1493 PF07377.12 EAX84713.1 - 0.029 14.8 0.6 0.076 13.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Fusion_gly PF00523.18 EAX84717.1 - 0.049 11.9 1.4 0.075 11.3 1.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3839 PF12943.7 EAX84723.1 - 1.4e-155 515.8 14.0 1.8e-155 515.5 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84723.1 - 0.044 14.2 1.7 0.13 12.7 0.2 2.0 2 0 0 2 2 2 0 Fez1 Glu-tRNAGln PF02686.15 EAX84723.1 - 0.3 11.4 1.6 0.97 9.8 0.5 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX84723.1 - 1.5 9.4 9.0 3.3 8.2 1.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84724.1 - 7e-155 513.5 12.4 8.8e-155 513.2 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84724.1 - 0.028 14.9 1.9 0.11 12.9 0.3 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX84724.1 - 0.043 14.1 1.5 13 6.1 0.1 3.7 3 1 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX84724.1 - 0.081 13.4 4.4 1.7 9.2 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84724.1 - 0.66 10.5 6.0 0.16 12.5 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX84725.1 - 2e-06 28.3 0.7 5.7e-06 26.8 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX84725.1 - 0.018 14.6 0.8 0.19 11.2 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX84726.1 - 2.3e-37 127.2 0.4 5.7e-37 126.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84726.1 - 0.005 17.5 0.1 0.013 16.1 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX84727.1 - 2.1e-156 518.5 13.3 2.7e-156 518.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX84727.1 - 0.86 10.2 4.7 1.3 9.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX84729.1 - 2.6e-73 245.5 4.3 3.1e-73 245.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX84729.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta KilA-N PF04383.13 EAX84730.1 - 3.1e-41 139.7 0.7 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX84730.1 - 0.38 10.8 2.6 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein RFX_DNA_binding PF02257.15 EAX84731.1 - 0.00028 21.5 0.2 0.00046 20.8 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX84731.1 - 0.00045 20.7 1.3 0.00069 20.1 1.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX84731.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PadR PF03551.14 EAX84733.1 - 0.059 13.3 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Pox_A32 PF04665.12 EAX84735.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84735.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84735.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84735.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84735.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84735.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84735.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84735.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84735.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84735.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84735.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84735.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84736.1 - 1.4e-40 137.6 0.5 3e-40 136.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84736.1 - 0.0043 17.7 0.3 0.016 15.8 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family DUF3839 PF12943.7 EAX84737.1 - 4.8e-123 409.3 6.3 5.9e-123 409.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84737.1 - 0.23 11.9 1.5 0.99 9.9 0.4 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5004 PF16395.5 EAX84739.1 - 0.019 15.0 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) Gly-zipper_Omp PF13488.6 EAX84742.1 - 0.0055 16.7 9.0 0.01 15.8 9.0 1.5 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX84742.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX84742.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Coatomer_g_Cpla PF16381.5 EAX84743.1 - 2.9e-19 69.3 1.2 6e-19 68.3 0.0 2.2 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 EAX84743.1 - 1.5e-18 67.3 2.4 1.8e-18 67.1 0.7 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 EAX84743.1 - 3e-07 30.7 0.2 5.7e-05 23.4 0.0 3.9 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EAX84743.1 - 0.034 14.6 0.2 0.85 10.2 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EAX84743.1 - 0.2 12.0 7.0 5.2 7.6 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat KilA-N PF04383.13 EAX84745.1 - 7.2e-07 29.1 0.1 1.9e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX84746.1 - 1.6e-57 194.7 1.4 1.9e-57 194.5 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX84747.1 - 1.1e-24 87.2 3.6 1.7e-24 86.6 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX84748.1 - 1.5e-06 28.6 0.1 3.9e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84748.1 - 0.059 13.2 1.6 0.17 11.8 0.9 2.2 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX84749.1 - 8.8e-136 451.0 11.9 1.1e-135 450.7 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX84749.1 - 0.55 10.7 3.0 5 7.7 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX84749.1 - 1.9 9.0 6.3 4.1 7.9 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sin_N PF04801.13 EAX84751.1 - 7.6e-29 101.2 3.0 8.2e-15 54.9 0.2 3.0 1 1 2 3 3 3 3 Sin-like protein conserved region MOZART1 PF12554.8 EAX84752.1 - 7.2e-22 76.9 1.3 8.2e-22 76.7 1.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated EcoEI_R_C PF08463.10 EAX84752.1 - 0.063 13.4 0.4 0.066 13.3 0.4 1.1 1 0 0 1 1 1 0 EcoEI R protein C-terminal CAP PF00188.26 EAX84753.1 - 5.4e-27 95.1 0.0 6.5e-10 39.9 0.0 3.3 3 0 0 3 3 3 3 Cysteine-rich secretory protein family DUF764 PF05561.11 EAX84753.1 - 0.058 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) TssO PF17561.2 EAX84753.1 - 0.077 13.1 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssO DUF2897 PF11446.8 EAX84754.1 - 1.8 8.5 3.7 3.3 7.7 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX84755.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84755.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84755.1 - 4.1e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84755.1 - 0.00014 21.9 3.4 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84755.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84755.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84755.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84755.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84755.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84755.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84755.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84755.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84756.1 - 4.5e-43 145.6 1.2 6.1e-43 145.2 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84756.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX84757.1 - 1.6e-06 28.6 0.1 4e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX84757.1 - 0.038 13.5 0.3 0.81 9.2 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX84758.1 - 3.2e-156 517.9 12.7 4.1e-156 517.6 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84758.1 - 0.035 14.6 1.0 0.22 11.9 0.2 2.1 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX84758.1 - 0.12 12.8 0.4 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX84758.1 - 0.18 12.3 5.8 2.5 8.6 0.7 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX84758.1 - 6.9 7.1 8.0 14 6.1 0.1 3.9 3 2 1 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX84760.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX84761.1 - 0.039 14.5 4.6 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX84762.1 - 0.033 14.6 0.5 0.085 13.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX84762.1 - 0.69 10.0 3.7 9.8 6.3 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX84763.1 - 4.2e-125 416.0 6.4 4.7e-125 415.9 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX84764.1 - 0.028 14.4 8.3 0.043 13.8 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84764.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX84765.1 - 0.17 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX84766.1 - 0.043 14.0 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3839 PF12943.7 EAX84767.1 - 8.9e-155 513.2 12.6 1.2e-154 512.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84767.1 - 0.39 11.2 5.8 2.5 8.6 1.0 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2666 PF10869.8 EAX84768.1 - 0.028 14.6 1.2 0.07 13.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF5446 PF17522.2 EAX84769.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Zn_ribbon_2 PF12674.7 EAX84770.1 - 0.024 15.3 4.3 0.83 10.4 0.4 2.9 1 1 1 2 2 2 0 Putative zinc ribbon domain PAS_7 PF12860.7 EAX84770.1 - 0.51 10.5 4.3 10 6.3 1.9 2.5 2 0 0 2 2 2 0 PAS fold MscS_porin PF12795.7 EAX84771.1 - 0.0055 16.3 17.7 0.0055 16.3 17.7 4.3 2 1 3 5 5 5 1 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.8 EAX84771.1 - 0.0073 16.5 5.3 0.0073 16.5 5.3 5.5 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EAX84771.1 - 3.6 8.1 19.8 12 6.4 0.1 7.1 4 3 1 5 5 5 0 Flagella accessory protein C (FlaC) PTR PF12789.7 EAX84772.1 - 1e-09 38.3 10.0 1.3e-08 34.7 5.6 4.2 5 0 0 5 5 5 2 Phage tail repeat like EMP24_GP25L PF01105.24 EAX84772.1 - 0.067 13.1 3.8 3.4 7.6 1.1 3.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD LIFR_D2 PF17971.1 EAX84772.1 - 0.072 13.3 0.1 10 6.3 0.0 2.4 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain IL2 PF00715.17 EAX84772.1 - 0.84 9.6 3.5 16 5.4 0.1 2.8 2 1 1 3 3 3 0 Interleukin 2 DUF4107 PF13389.6 EAX84773.1 - 1.5e-72 243.0 4.2 2e-72 242.6 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ras PF00071.22 EAX84774.1 - 1.9e-44 151.1 0.0 2.2e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX84774.1 - 1.1e-32 112.8 0.0 1.4e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX84774.1 - 4.7e-15 55.5 0.0 6.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX84774.1 - 1.6e-05 24.4 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX84774.1 - 3e-05 23.6 0.1 0.00068 19.2 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX84774.1 - 0.00011 22.2 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX84774.1 - 0.00032 20.8 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX84774.1 - 0.0021 17.8 0.1 0.005 16.6 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX84774.1 - 0.0077 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 EAX84774.1 - 0.0082 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX84774.1 - 0.083 13.3 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF4408 PF14364.6 EAX84774.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) ATP_bind_1 PF03029.17 EAX84774.1 - 0.12 12.1 0.2 15 5.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EAX84774.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Thioredoxin PF00085.20 EAX84775.1 - 1.9e-18 66.4 0.1 2.2e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EAX84775.1 - 0.00016 21.6 0.2 0.00037 20.4 0.2 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EAX84775.1 - 0.00023 21.4 0.7 0.052 13.9 0.2 2.2 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EAX84775.1 - 0.0004 19.8 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EAX84775.1 - 0.00061 19.9 0.0 0.00097 19.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EAX84775.1 - 0.0014 18.4 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_3 PF13192.6 EAX84775.1 - 0.0034 17.4 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DIM1 PF02966.16 EAX84775.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 EAX84775.1 - 0.012 16.1 0.1 0.019 15.4 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 EAX84775.1 - 0.013 15.9 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Carb_anhydrase PF00194.21 EAX84775.1 - 0.025 14.1 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Thioredoxin_9 PF14595.6 EAX84775.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Pox_A32 PF04665.12 EAX84776.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84776.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX84776.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX84776.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX84776.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX84776.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX84776.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Pox_A32 PF04665.12 EAX84777.1 - 1.4e-06 28.0 2.1 1.4e-06 28.0 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84777.1 - 3.3e-05 23.7 0.3 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84777.1 - 4.7e-05 23.7 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84777.1 - 0.00036 20.6 4.4 0.00061 19.8 3.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84777.1 - 0.00076 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84777.1 - 0.0026 17.6 1.1 0.0059 16.4 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84777.1 - 0.0055 16.4 2.6 0.015 14.9 0.4 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84777.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX84777.1 - 0.085 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX84777.1 - 0.092 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84777.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84777.1 - 0.11 12.9 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX84777.1 - 0.61 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2805 PF10985.8 EAX84777.1 - 0.86 10.0 0.0 0.86 10.0 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2805) DUF573 PF04504.14 EAX84777.1 - 1.8 9.3 11.7 0.34 11.6 1.7 3.5 3 1 1 4 4 4 0 Protein of unknown function, DUF573 KilA-N PF04383.13 EAX84778.1 - 2.7e-41 139.9 1.1 4.6e-41 139.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX84778.1 - 0.0094 15.2 0.2 0.038 13.2 0.1 1.8 1 1 1 2 2 2 1 Acyl transferase DUF3213 PF11491.8 EAX84778.1 - 0.0097 16.1 0.1 0.031 14.4 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX84778.1 - 0.13 10.7 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX84779.1 - 3.2e-155 514.7 12.9 3.9e-155 514.4 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX84779.1 - 0.3 11.4 3.5 1.6 9.1 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain Glu-tRNAGln PF02686.15 EAX84779.1 - 0.32 11.3 2.7 0.68 10.3 1.0 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX84779.1 - 0.47 10.9 5.9 4.4 7.8 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84779.1 - 2.3 8.8 5.8 1.2 9.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4795 PF16043.5 EAX84780.1 - 0.00038 20.1 14.6 0.0084 15.7 3.3 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) Poxvirus_B22R_C PF13168.6 EAX84780.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal PTR PF12789.7 EAX84780.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.7 4 0 0 4 4 4 0 Phage tail repeat like DUF3839 PF12943.7 EAX84781.1 - 5e-153 507.5 11.7 6.2e-153 507.2 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX84781.1 - 0.42 10.9 3.8 13 6.2 0.0 3.7 5 1 0 5 5 5 0 Tup N-terminal FKBP_N PF01346.18 EAX84781.1 - 0.43 11.6 2.5 0.51 11.3 0.3 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase T5orf172 PF10544.9 EAX84782.1 - 0.012 16.1 0.9 0.032 14.8 0.2 1.9 2 0 0 2 2 2 0 T5orf172 domain Baculo_ME53 PF06061.11 EAX84782.1 - 0.029 13.6 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 KilA-N PF04383.13 EAX84782.1 - 0.04 13.8 0.3 0.088 12.7 0.3 1.7 1 1 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX84782.1 - 0.048 13.2 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Legume lectin domain Apolipoprotein PF01442.18 EAX84784.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Antimicrobial_7 PF08102.11 EAX84784.1 - 0.14 12.4 0.9 0.14 12.4 0.9 2.1 1 1 1 2 2 2 0 Scorpion antimicrobial peptide DNA_pol_B_2 PF03175.13 EAX84785.1 - 1.8e-09 37.0 2.0 2.9e-09 36.3 1.3 1.6 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX84786.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX84786.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX84787.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84787.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX84788.1 - 0.008 16.2 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX84788.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal PSP PF04046.16 EAX84789.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX84790.1 - 0.068 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Mito_fiss_reg PF05308.11 EAX84792.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX84792.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4108 PF13390.6 EAX84793.1 - 1.3e-52 177.5 6.1 1.5e-52 177.4 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Zn_peptidase PF04228.13 EAX84794.1 - 0.21 11.0 0.8 2.2 7.6 0.1 2.0 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase ABC_membrane PF00664.23 EAX84795.1 - 5.6e-37 127.9 6.6 8.4e-37 127.3 6.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX84795.1 - 2.9e-31 108.8 0.0 5.7e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX84795.1 - 8.8e-09 35.1 2.7 4e-08 33.0 2.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAX84795.1 - 0.0002 21.6 0.0 0.00067 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX84795.1 - 0.00094 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAX84795.1 - 0.00096 18.8 0.0 0.0028 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAX84795.1 - 0.0041 17.0 0.2 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EAX84795.1 - 0.0042 16.8 0.2 0.0042 16.8 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EAX84795.1 - 0.0051 16.1 0.3 0.071 12.4 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 EAX84795.1 - 0.014 14.6 0.3 0.029 13.5 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_21 PF13304.6 EAX84795.1 - 0.042 13.7 0.1 0.68 9.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EAX84795.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAX84795.1 - 0.076 12.4 0.4 0.55 9.5 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EAX84795.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EAX84795.1 - 0.2 12.1 1.7 0.54 10.7 0.1 2.3 2 1 1 3 3 3 0 AAA domain DUF5616 PF18481.1 EAX84795.1 - 0.29 11.5 3.0 2.1 8.7 0.3 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF5616) PSP PF04046.16 EAX84796.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Sec1 PF00995.23 EAX84798.1 - 3.8e-91 307.1 6.4 4.4e-91 306.9 6.4 1.0 1 0 0 1 1 1 1 Sec1 family DUF1947 PF09183.10 EAX84800.1 - 0.0048 17.2 0.2 0.069 13.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) Ank_2 PF12796.7 EAX84802.1 - 1.2e-47 160.3 0.2 3.1e-22 79.0 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX84802.1 - 3.8e-38 128.3 0.0 5.7e-05 23.4 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX84802.1 - 4.3e-36 122.5 0.4 1.5e-08 34.7 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX84802.1 - 3.6e-35 119.9 0.1 1.1e-09 38.6 0.0 4.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84802.1 - 4.7e-32 106.4 0.0 0.0013 19.0 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat L_protein_N PF15518.6 EAX84802.1 - 0.00011 22.0 1.2 0.74 9.7 0.0 5.0 3 1 1 4 4 4 1 L protein N-terminus DUF4515 PF14988.6 EAX84802.1 - 0.0099 15.7 1.6 0.018 14.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) HEAT PF02985.22 EAX84803.1 - 3.6e-05 23.7 0.1 0.004 17.3 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 EAX84803.1 - 0.00063 19.4 1.1 0.018 14.6 0.0 3.4 3 2 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 EAX84803.1 - 0.0036 17.4 5.0 0.12 12.4 0.1 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 EAX84803.1 - 0.0094 15.7 0.2 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EAX84803.1 - 0.011 16.1 0.0 0.11 12.9 0.0 2.8 1 0 0 1 1 1 0 HEAT repeats FANCI_S2 PF14676.6 EAX84803.1 - 0.012 15.9 1.6 1.8 8.9 1.4 3.5 2 1 0 2 2 2 0 FANCI solenoid 2 SPG48 PF14764.6 EAX84803.1 - 0.029 14.8 1.5 0.23 11.9 0.2 3.2 2 1 1 3 3 3 0 AP-5 complex subunit, vesicle trafficking HEAT_EZ PF13513.6 EAX84803.1 - 0.12 12.9 0.0 0.78 10.3 0.0 2.5 1 0 0 1 1 1 0 HEAT-like repeat Glutaminase PF04960.15 EAX84803.1 - 0.15 11.2 0.9 3.3 6.8 0.1 3.0 3 1 0 3 3 3 0 Glutaminase alpha-hel2 PF14456.6 EAX84803.1 - 1.5 8.1 5.0 2 7.6 0.0 2.9 3 0 0 3 3 3 0 Alpha-helical domain 2 RTP1_C1 PF10363.9 EAX84803.1 - 3.8 7.7 6.1 17 5.6 0.7 4.2 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-3CxxC PF13695.6 EAX84804.1 - 0.078 13.5 2.6 0.095 13.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-binding domain Sugarporin_N PF11471.8 EAX84804.1 - 0.1 12.6 1.5 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF2316 PF10078.9 EAX84804.1 - 0.11 12.8 1.8 0.82 10.0 0.1 3.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) TetR_C_34 PF17929.1 EAX84804.1 - 0.11 12.6 0.0 0.51 10.4 0.0 2.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PSII_Pbs27 PF13326.6 EAX84804.1 - 0.12 12.7 9.0 6.8 7.0 0.1 4.1 3 2 1 4 4 4 0 Photosystem II Pbs27 HAND PF09110.11 EAX84804.1 - 0.28 11.9 0.1 0.28 11.9 0.1 3.0 2 0 0 2 2 2 0 HAND DNTTIP1_dimer PF18192.1 EAX84804.1 - 5.1 7.5 10.3 0.25 11.7 1.0 3.5 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain Ima1_N PF09779.9 EAX84804.1 - 6.9 7.5 10.1 0.73 10.7 1.4 3.3 2 1 0 3 3 3 0 Ima1 N-terminal domain Pro_isomerase PF00160.21 EAX84805.1 - 2.7e-08 34.2 0.0 4.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4885 PF16226.5 EAX84805.1 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) zf-NOSIP PF15906.5 EAX84805.1 - 0.033 14.3 0.0 0.092 12.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein DUF4315 PF14193.6 EAX84805.1 - 0.081 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) TPR_19 PF14559.6 EAX84806.1 - 3.8e-11 43.3 0.1 0.0027 18.2 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX84806.1 - 1.3e-10 41.2 0.4 0.06 14.2 0.0 7.5 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX84806.1 - 1.5e-05 24.3 0.7 0.097 11.9 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX84806.1 - 3.7e-05 23.9 0.7 1.5 9.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAX84806.1 - 0.00078 20.0 0.0 1.1 10.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX84806.1 - 0.00088 19.3 8.9 4.4 7.8 0.2 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EAX84806.1 - 0.002 18.1 2.3 3.1 7.8 0.0 4.3 3 1 2 5 5 5 1 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 EAX84806.1 - 0.0095 16.1 2.1 2.2 8.6 0.1 3.5 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EAX84806.1 - 0.016 15.2 1.1 5.6 7.2 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX84806.1 - 0.022 14.8 4.1 34 4.9 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CH PF00307.31 EAX84806.1 - 0.026 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Calponin homology (CH) domain RPN7 PF10602.9 EAX84806.1 - 0.026 14.2 3.1 0.32 10.7 0.3 3.4 4 2 2 6 6 6 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 EAX84806.1 - 0.033 14.6 0.3 0.44 11.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RmuC PF02646.16 EAX84806.1 - 0.053 12.7 2.0 6.1 5.9 0.1 2.4 2 0 0 2 2 2 0 RmuC family DnaB PF00772.21 EAX84806.1 - 0.11 12.6 0.1 14 5.8 0.0 3.3 2 1 1 3 3 3 0 DnaB-like helicase N terminal domain TPR_6 PF13174.6 EAX84806.1 - 1.2 9.9 3.4 4.7 8.1 0.2 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat Pox_A32 PF04665.12 EAX84807.1 - 5.5e-08 32.6 0.9 6.5e-08 32.3 0.9 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX84807.1 - 0.0041 16.8 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX84807.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX84807.1 - 0.07 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX84808.1 - 4.1e-25 88.6 3.6 6.1e-25 88.1 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX84808.1 - 0.028 14.7 0.7 0.081 13.2 0.1 1.9 1 1 1 2 2 2 0 PRD domain SLT_2 PF13406.6 EAX84810.1 - 0.079 12.2 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Gly_rich PF12810.7 EAX84811.1 - 1.1e-17 64.8 13.7 1.2e-17 64.6 13.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Trypan_PARP PF05887.11 EAX84815.1 - 0.036 14.1 10.9 0.05 13.6 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX84816.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta RRM_1 PF00076.22 EAX84817.1 - 3.6e-36 122.8 0.5 1.1e-16 60.4 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX84817.1 - 4.8e-08 32.7 0.1 9.8e-05 22.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX84817.1 - 3.3e-06 27.1 0.2 0.0044 17.1 0.0 3.7 3 1 1 4 4 4 1 RNA recognition motif BRAP2 PF07576.12 EAX84817.1 - 8.8e-05 22.7 0.4 0.00057 20.0 0.0 2.4 4 0 0 4 4 4 1 BRCA1-associated protein 2 RRM_occluded PF16842.5 EAX84817.1 - 0.034 14.0 0.2 2.3 8.1 0.0 3.3 4 0 0 4 4 4 0 Occluded RNA-recognition motif DUF1664 PF07889.12 EAX84819.1 - 0.13 12.3 3.4 0.23 11.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 EAX84820.1 - 9.1e-57 192.4 0.0 1.7e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84820.1 - 5.3e-29 101.3 0.0 2.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX84820.1 - 5.4e-08 32.2 4.1 1.2e-07 31.1 4.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 EAX84820.1 - 0.00032 21.3 0.1 0.00032 21.3 0.1 2.3 3 0 0 3 3 3 1 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 EAX84820.1 - 0.0019 17.3 0.1 0.0035 16.4 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EAX84820.1 - 0.0096 15.9 0.1 0.029 14.3 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX84820.1 - 0.033 13.5 0.1 0.075 12.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX84820.1 - 0.035 13.4 0.6 3.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Kinase-like His_Phos_2 PF00328.22 EAX84821.1 - 9.4e-20 71.3 0.1 8.8e-11 41.8 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TPR_14 PF13428.6 EAX84822.1 - 1.7e-06 28.4 0.4 0.028 15.2 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAX84822.1 - 1e-05 26.0 0.0 0.24 11.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX84822.1 - 0.0011 19.0 0.8 2.2 8.7 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX84822.1 - 0.0076 15.5 0.4 0.018 14.3 0.4 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.9 EAX84822.1 - 0.018 14.7 0.9 0.15 11.7 0.2 2.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 EAX84822.1 - 0.03 15.0 0.0 0.49 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAX84822.1 - 0.073 13.1 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2205 PF10224.9 EAX84822.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Short coiled-coil protein PolyA_pol PF01743.20 EAX84823.1 - 1.5e-25 90.1 0.0 2.7e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAX84823.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF1679 PF07914.11 EAX84823.1 - 0.019 13.8 0.1 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MbtH PF03621.13 EAX84823.1 - 0.058 12.9 1.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 MbtH-like protein Spo12 PF05032.12 EAX84827.1 - 6.4 6.8 13.2 0.21 11.5 2.9 3.1 4 0 0 4 4 4 0 Spo12 family Amidase02_C PF12123.8 EAX84828.1 - 0.0027 17.3 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX84828.1 - 0.17 11.8 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX84829.1 - 3.8e-157 521.0 13.1 4.7e-157 520.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84829.1 - 0.06 13.8 1.6 0.31 11.5 0.3 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX84829.1 - 0.16 11.8 1.9 0.4 10.5 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84829.1 - 4.5 7.8 6.9 4.4 7.8 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84830.1 - 8.8e-155 513.2 14.4 1.1e-154 513.0 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4917 PF16263.5 EAX84830.1 - 0.021 14.2 0.1 0.04 13.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4917) Rx_N PF18052.1 EAX84830.1 - 0.43 10.9 3.6 1.4 9.2 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84830.1 - 0.85 10.1 7.6 2.1 8.8 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX84831.1 - 6.5e-157 520.2 13.1 8.1e-157 519.9 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84831.1 - 0.02 15.4 1.4 0.12 12.8 0.2 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX84831.1 - 0.4 11.2 6.5 0.15 12.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX84831.1 - 0.42 11.1 6.9 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX84832.1 - 1e-41 141.3 1.3 1.3e-41 140.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84832.1 - 0.028 14.6 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Amidase02_C PF12123.8 EAX84833.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase CreA PF05981.12 EAX84833.1 - 0.049 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 CreA protein DUF4107 PF13389.6 EAX84834.1 - 2.2e-26 93.0 2.1 2.6e-26 92.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX84835.1 - 4.4e-28 98.5 2.3 7.2e-28 97.8 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) RhoGAP PF00620.27 EAX84836.1 - 9.4e-31 106.7 0.0 2.8e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 EAX84836.1 - 6.6e-16 58.7 0.0 9.1e-14 51.9 0.0 2.6 2 0 0 2 2 2 1 MyTH4 domain ApoA-II PF04711.13 EAX84836.1 - 0.054 13.7 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) WW PF00397.26 EAX84836.1 - 0.28 11.3 8.7 0.08 13.1 4.6 2.2 2 0 0 2 2 2 0 WW domain Beta_helix PF13229.6 EAX84838.1 - 1.4e-11 44.5 25.7 4.2e-08 33.2 5.9 4.6 4 2 0 5 5 5 2 Right handed beta helix region NosD PF05048.13 EAX84838.1 - 0.0016 17.7 17.9 0.0016 17.7 17.9 3.8 4 1 1 5 5 5 2 Periplasmic copper-binding protein (NosD) DUF5123 PF17161.4 EAX84838.1 - 0.49 11.5 14.6 0.6 11.2 0.7 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5123) DUF5365 PF17326.2 EAX84841.1 - 0.027 14.9 0.1 0.07 13.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX84841.1 - 0.037 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 PWI domain DDR PF08841.10 EAX84844.1 - 0.048 12.6 0.3 0.05 12.6 0.3 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MULE PF10551.9 EAX84846.1 - 1.6e-13 50.9 2.7 1.8e-13 50.7 0.5 2.1 2 1 1 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX84846.1 - 0.039 13.7 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EAX84846.1 - 0.073 11.9 0.1 0.084 11.7 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family KilA-N PF04383.13 EAX84847.1 - 3e-35 120.4 0.6 6.1e-35 119.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX84848.1 - 1.1e-06 29.2 0.1 2.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84848.1 - 0.021 14.7 1.5 0.14 12.0 0.6 2.6 2 1 0 2 2 2 0 KilA-N domain UN_NPL4 PF11543.8 EAX84849.1 - 0.09 13.3 0.3 0.22 12.0 0.3 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Kinocilin PF15033.6 EAX84849.1 - 0.091 12.4 0.1 44 3.7 0.0 3.6 3 1 0 4 4 4 0 Kinocilin protein DUF3839 PF12943.7 EAX84850.1 - 3.5e-142 471.9 9.5 5.6e-142 471.3 9.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84850.1 - 1.4 9.4 6.7 2.4 8.7 1.3 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4116 PF13475.6 EAX84851.1 - 0.081 12.7 0.1 0.33 10.7 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PTR PF12789.7 EAX84851.1 - 0.34 11.0 0.2 0.34 11.0 0.2 5.2 5 1 0 5 5 5 0 Phage tail repeat like YmaF PF12788.7 EAX84851.1 - 0.56 10.8 8.3 0.93 10.1 0.3 3.4 3 1 0 4 4 4 0 YmaF family Gp5_C PF06715.12 EAX84851.1 - 0.78 10.0 3.8 1.7 8.9 0.3 3.3 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Phage_fiber PF03335.13 EAX84851.1 - 5.7 7.4 17.6 5.9 7.4 1.1 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX84852.1 - 0.037 14.5 0.6 0.088 13.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX84853.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX84854.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP DUF3781 PF12636.7 EAX84855.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX84856.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX84857.1 - 1.5e-155 515.7 12.2 1.9e-155 515.4 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84857.1 - 1.8 9.1 4.9 4.9 7.7 0.3 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX84859.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX84860.1 - 9.3e-07 28.5 1.9 9.3e-07 28.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84860.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84860.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84860.1 - 0.00019 21.5 3.6 0.00045 20.3 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84860.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84860.1 - 0.0017 18.2 0.6 0.0044 16.8 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84860.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84860.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84860.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84860.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84860.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX84860.1 - 0.25 11.8 3.2 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX84860.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84861.1 - 2e-35 121.0 1.5 2.3e-35 120.8 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX84861.1 - 0.025 14.7 0.0 0.086 13.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX84861.1 - 5.3 7.6 9.2 13 6.3 3.6 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PTR PF12789.7 EAX84863.1 - 1.3e-18 66.8 2.2 1.3e-18 66.8 2.2 3.6 3 1 1 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX84863.1 - 0.029 14.1 0.2 0.25 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX84863.1 - 1.2 8.7 17.3 0.068 12.8 3.4 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) B56 PF01603.20 EAX84865.1 - 7.3e-53 180.0 14.4 8.3e-53 179.8 14.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd3 PF12719.7 EAX84865.1 - 0.01 15.1 6.0 0.76 8.9 0.4 3.1 2 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain B56 PF01603.20 EAX84866.1 - 0.022 13.7 0.2 0.029 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pox_A32 PF04665.12 EAX84867.1 - 8.5e-07 28.7 2.5 8.5e-07 28.7 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84867.1 - 3.3e-05 23.7 0.3 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84867.1 - 4.6e-05 23.7 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84867.1 - 0.00028 20.9 4.1 0.00058 19.9 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84867.1 - 0.00076 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84867.1 - 0.0024 17.7 1.2 0.0043 16.9 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84867.1 - 0.0065 16.1 2.9 0.016 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84867.1 - 0.015 15.7 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX84867.1 - 0.084 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX84867.1 - 0.091 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84867.1 - 0.11 12.9 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84867.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84867.1 - 0.61 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX84867.1 - 0.72 10.6 11.7 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 KilA-N PF04383.13 EAX84868.1 - 5.5e-28 97.1 0.0 7.8e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX84869.1 - 1.9e-07 31.6 0.4 3.9e-07 30.6 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX84869.1 - 0.12 13.0 0.3 0.33 11.7 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX84871.1 - 1.1e-33 115.4 0.1 1.3e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain DDE_1 PF03184.19 EAX84872.1 - 5.3e-15 55.5 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Pox_A32 PF04665.12 EAX84874.1 - 5.4e-07 29.3 2.2 5.4e-07 29.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84874.1 - 3e-05 24.3 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84874.1 - 0.00017 21.7 3.6 0.0004 20.4 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX84874.1 - 0.00024 20.9 0.3 0.39 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_11 PF13086.6 EAX84874.1 - 0.00063 19.6 0.4 0.00098 19.0 0.4 1.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX84874.1 - 0.00065 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX84874.1 - 0.0021 17.8 0.4 0.012 15.2 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84874.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84874.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84874.1 - 0.087 13.2 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84874.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein KilA-N PF04383.13 EAX84875.1 - 7.9e-07 28.9 2.5 8.4e-07 28.8 0.2 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84875.1 - 0.0024 18.5 0.0 0.0049 17.5 0.0 1.6 2 0 0 2 2 2 1 Parathyroid hormone family DUF1493 PF07377.12 EAX84876.1 - 0.016 15.7 0.5 0.028 14.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX84877.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX84878.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4106 PF13388.6 EAX84879.1 - 1.6e-94 317.5 4.8 1.9e-94 317.3 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Rgp1 PF08737.10 EAX84880.1 - 1.9 7.5 12.1 1.9 7.5 12.1 1.0 1 0 0 1 1 1 0 Rgp1 Pox_A32 PF04665.12 EAX84881.1 - 7.5e-07 28.9 2.4 7.5e-07 28.9 2.4 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX84881.1 - 4e-05 23.4 0.3 0.4 10.4 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX84881.1 - 4.6e-05 23.7 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX84881.1 - 0.00028 20.9 4.1 0.00065 19.7 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84881.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84881.1 - 0.0023 17.8 1.0 0.0046 16.8 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84881.1 - 0.0067 16.1 3.1 0.016 14.9 0.2 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84881.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX84881.1 - 0.092 12.3 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX84881.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX84881.1 - 0.11 12.9 0.1 0.95 9.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX84881.1 - 0.13 12.3 0.7 1.7 8.7 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1827 PF08860.10 EAX84881.1 - 1.1 9.5 5.3 11 6.4 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX84881.1 - 2.1 9.1 12.4 0.89 10.2 2.2 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Mito_fiss_reg PF05308.11 EAX84883.1 - 0.077 13.1 0.4 0.083 13.0 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX84883.1 - 0.63 9.5 2.6 0.62 9.5 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_2 PF12796.7 EAX84884.1 - 1.5e-70 233.8 1.3 2e-18 66.8 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84884.1 - 2.4e-40 136.4 0.0 1.9e-10 41.0 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX84884.1 - 1.6e-33 114.3 0.0 6.3e-07 29.6 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX84884.1 - 6.5e-33 111.7 0.0 4.6e-05 23.7 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAX84884.1 - 4.5e-26 88.1 0.0 0.0034 17.7 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat YgaB PF14182.6 EAX84884.1 - 0.077 13.4 0.9 0.16 12.4 0.9 1.5 1 0 0 1 1 1 0 YgaB-like protein DUF1147 PF06615.11 EAX84884.1 - 0.3 11.2 0.7 2.2 8.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1147) DUF4844 PF16133.5 EAX84884.1 - 0.31 11.6 4.6 0.21 12.1 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) DNTTIP1_dimer PF18192.1 EAX84885.1 - 0.16 12.3 2.1 3.2 8.2 0.4 2.7 1 1 1 2 2 2 0 DNTTIP1 dimerisation domain Ank_2 PF12796.7 EAX84886.1 - 1.2e-08 35.4 0.0 7.9e-07 29.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84886.1 - 6.2e-07 29.8 0.1 0.00011 22.7 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84886.1 - 0.00021 21.5 0.0 1.5 9.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX84886.1 - 0.0019 18.4 0.0 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LisH_TPL PF17814.1 EAX84886.1 - 0.07 12.8 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain Ank PF00023.30 EAX84886.1 - 0.076 13.5 0.0 0.6 10.7 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat DUF3447 PF11929.8 EAX84886.1 - 0.093 12.7 2.7 0.2 11.7 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) PSP PF04046.16 EAX84887.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX84888.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX84890.1 - 7.6e-159 526.5 13.4 9.5e-159 526.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX84890.1 - 0.1 13.0 0.3 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX84890.1 - 0.3 11.4 3.4 14 6.1 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX84890.1 - 1.3 9.6 7.6 2 8.9 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Peptidase_M8 PF01457.16 EAX84891.1 - 0.0069 15.1 0.0 0.0069 15.1 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Med18 PF09637.10 EAX84893.1 - 0.05 13.4 0.1 0.076 12.8 0.1 1.1 1 0 0 1 1 1 0 Med18 protein KilA-N PF04383.13 EAX84894.1 - 1.5e-34 118.2 1.1 2.4e-34 117.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84894.1 - 0.0046 17.6 0.1 0.012 16.2 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family COMP PF11598.8 EAX84894.1 - 0.064 13.7 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein T5orf172 PF10544.9 EAX84895.1 - 4e-06 27.3 0.1 9.7e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84895.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX84895.1 - 0.0093 15.5 0.3 0.07 12.7 0.1 1.9 2 0 0 2 2 2 1 Legume lectin domain DUF3839 PF12943.7 EAX84896.1 - 3.2e-157 521.2 11.1 4.1e-157 520.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84896.1 - 0.14 12.6 2.2 0.24 11.8 0.5 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84896.1 - 0.25 11.8 4.8 5 7.6 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX84896.1 - 0.35 11.2 0.1 0.35 11.2 0.1 2.6 4 0 0 4 4 4 0 PRD domain DUF3447 PF11929.8 EAX84897.1 - 0.0005 20.0 0.8 0.0005 20.0 0.8 4.1 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX84897.1 - 0.011 16.4 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX84898.1 - 4.5e-17 62.4 5.1 3.8e-09 37.0 2.3 4.1 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84898.1 - 3.3e-13 49.8 3.0 8e-05 23.1 0.4 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX84898.1 - 1.3e-07 31.8 1.7 0.15 12.4 0.2 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84898.1 - 6.8e-07 29.1 12.7 0.05 14.2 0.1 6.6 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EAX84898.1 - 4.1e-06 27.0 2.2 8 7.1 0.0 5.4 4 1 1 5 5 5 2 Ankyrin repeat DUF249 PF03158.13 EAX84898.1 - 0.0048 16.6 6.4 0.72 9.5 1.3 3.1 3 1 0 3 3 3 2 Multigene family 530 protein PUB PF09409.10 EAX84898.1 - 0.026 14.4 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 PUB domain FAS_N PF17828.1 EAX84900.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta LRR_5 PF13306.6 EAX84902.1 - 1.5e-57 193.1 51.8 2.2e-30 105.2 15.7 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84902.1 - 1.5e-12 47.1 4.9 0.026 14.3 0.5 5.8 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EAX84902.1 - 0.12 12.8 10.4 0.47 11.0 0.2 5.3 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX84903.1 - 1.6e-45 154.2 26.9 9.6e-22 77.3 8.9 3.5 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX84903.1 - 9.1e-10 38.2 0.6 0.0001 22.0 0.0 4.6 3 2 1 4 4 4 2 Leucine rich repeat RNA_lig_T4_1 PF09511.10 EAX84904.1 - 0.09 12.6 2.6 0.17 11.7 2.6 1.5 1 1 0 1 1 1 0 RNA ligase BNIP2 PF12496.8 EAX84904.1 - 0.11 13.0 3.6 0.19 12.2 3.6 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF885 PF05960.11 EAX84904.1 - 0.19 11.4 0.5 0.27 10.8 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) VIT1 PF01988.19 EAX84904.1 - 0.56 10.0 1.8 1.9 8.3 0.0 1.9 2 0 0 2 2 2 0 VIT family dsRBD2 PF17842.1 EAX84904.1 - 4.1 7.6 6.5 0.99 9.6 1.4 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 NRIP1_repr_3 PF15689.5 EAX84904.1 - 8.6 6.7 11.5 0.73 10.2 2.2 2.9 2 1 1 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 PTR PF12789.7 EAX84905.1 - 1.1e-65 217.5 47.4 2.1e-31 107.7 13.5 6.4 4 2 2 6 6 6 3 Phage tail repeat like DUF4795 PF16043.5 EAX84905.1 - 1.8 8.1 13.6 5.9 6.4 10.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX84906.1 - 2.2e-156 518.5 13.7 2.7e-156 518.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84906.1 - 0.18 11.7 1.3 0.47 10.3 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX84906.1 - 0.38 11.1 3.3 1.6 9.0 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX84906.1 - 0.42 11.1 6.7 2.5 8.6 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84906.1 - 3.9 8.0 6.5 1.1 9.8 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX84906.1 - 5.2 7.4 7.5 15 6.0 0.1 3.9 3 2 2 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX84907.1 - 7.1e-06 26.5 0.6 2.1e-05 25.0 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX84907.1 - 0.0054 16.0 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX84907.1 - 0.0062 16.1 0.3 0.76 9.3 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain PTR PF12789.7 EAX84908.1 - 6.5e-17 61.3 27.1 4.1e-08 33.2 4.8 6.0 6 0 0 6 6 6 4 Phage tail repeat like Collagen PF01391.18 EAX84908.1 - 2.2e-08 33.8 18.6 3.4e-08 33.1 18.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX84908.1 - 0.012 15.7 3.5 0.042 13.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RecG_N PF17190.4 EAX84908.1 - 0.22 12.3 2.2 55 4.6 0.0 4.4 4 0 0 4 4 4 0 RecG N-terminal helical domain Baculo_PEP_C PF04513.12 EAX84908.1 - 0.25 11.4 9.2 1.7 8.6 0.5 4.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EAX84908.1 - 0.97 9.7 3.5 1.3 9.3 0.1 3.1 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 EAX84908.1 - 1.4 8.5 13.5 6.1 6.4 0.1 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4795) DNA_pol_B_2 PF03175.13 EAX84909.1 - 2.8e-09 36.4 0.8 5.4e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX84909.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX84910.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX84911.1 - 0.018 15.4 0.8 0.026 14.9 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84911.1 - 3.1 7.8 5.3 3.3 7.7 5.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pkinase PF00069.25 EAX84912.1 - 1.6e-64 217.8 0.7 2.6e-64 217.1 0.7 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX84912.1 - 3.1e-44 151.2 0.2 4.4e-44 150.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX84912.1 - 2.8e-07 30.2 0.0 3.6e-06 26.5 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX84912.1 - 3e-05 23.5 0.1 9.2e-05 21.9 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX84912.1 - 7.8e-05 22.7 0.2 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX84912.1 - 0.0009 18.1 0.3 0.0015 17.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX84912.1 - 0.0011 18.6 0.9 0.0027 17.3 0.9 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EAX84912.1 - 0.0059 15.6 0.6 0.0095 14.9 0.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAX84912.1 - 0.0066 15.5 1.2 0.012 14.7 0.1 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 EAX84912.1 - 0.059 13.0 0.1 0.17 11.5 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 EAX84912.1 - 0.075 12.7 0.3 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 BLOC1_2 PF10046.9 EAX84913.1 - 0.0013 18.9 0.5 0.0015 18.8 0.5 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EAX84913.1 - 0.0026 18.0 0.2 0.0031 17.7 0.2 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Mod_r PF07200.13 EAX84913.1 - 0.012 15.7 0.3 0.014 15.5 0.3 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HeLo PF14479.6 EAX84913.1 - 0.03 14.2 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation FlgN PF05130.12 EAX84913.1 - 0.041 14.4 0.1 0.045 14.3 0.1 1.1 1 0 0 1 1 1 0 FlgN protein Spc7 PF08317.11 EAX84917.1 - 0.004 16.1 19.9 0.004 16.1 19.9 8.5 3 2 7 10 10 10 5 Spc7 kinetochore protein SHE3 PF17078.5 EAX84917.1 - 0.0047 16.7 29.6 0.0047 16.7 29.6 7.9 3 2 5 8 8 8 2 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 EAX84917.1 - 0.0085 16.4 8.6 0.0085 16.4 8.6 16.5 6 4 9 17 17 17 3 Csm1 N-terminal domain VP9 PF09625.10 EAX84917.1 - 0.079 13.1 6.4 0.41 10.9 1.3 3.6 3 0 0 3 3 3 0 VP9 protein MT0933_antitox PF14013.6 EAX84917.1 - 0.16 12.3 3.0 0.48 10.8 0.1 3.4 3 0 0 3 3 3 0 MT0933-like antitoxin protein TTRAP PF14203.6 EAX84919.1 - 0.04 13.9 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Trypan_PARP PF05887.11 EAX84920.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84920.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX84921.1 - 0.063 12.3 0.1 0.065 12.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain SL4P PF17618.2 EAX84924.1 - 0.21 11.6 3.1 6.4 6.9 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Gly-zipper_Omp PF13488.6 EAX84926.1 - 0.0062 16.5 7.8 0.01 15.8 7.8 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX84926.1 - 0.24 11.7 4.3 0.38 11.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) KilA-N PF04383.13 EAX84927.1 - 3.2e-40 136.5 1.3 4.5e-40 136.0 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84927.1 - 0.041 14.5 0.2 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX84928.1 - 2.5e-06 28.0 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84928.1 - 0.019 14.8 1.0 0.063 13.1 0.4 2.2 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX84929.1 - 4.2e-07 29.7 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MutS_IV PF05190.18 EAX84930.1 - 0.17 12.2 0.5 13 6.2 0.0 2.1 2 0 0 2 2 2 0 MutS family domain IV Phage_fiber PF03335.13 EAX84930.1 - 0.4 11.0 4.9 4 7.9 0.3 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat BphX PF06139.12 EAX84931.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 BphX-like Beta_helix PF13229.6 EAX84933.1 - 1.1e-41 142.3 59.8 2.1e-13 50.4 8.4 4.7 2 2 2 4 4 4 4 Right handed beta helix region GFO_IDH_MocA PF01408.22 EAX84934.1 - 1.2e-24 87.5 0.0 2.1e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAX84934.1 - 2.8e-05 24.1 0.0 6.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peptidase_C1 PF00112.23 EAX84935.1 - 2.2e-73 246.9 5.0 2.5e-73 246.8 5.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX84935.1 - 9.7e-06 24.6 0.6 0.0051 15.7 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF4107 PF13389.6 EAX84937.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX84937.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase PLAC8 PF04749.17 EAX84938.1 - 1.6e-10 41.9 9.7 2.1e-10 41.5 9.7 1.2 1 0 0 1 1 1 1 PLAC8 family CCDC32 PF14989.6 EAX84940.1 - 0.0037 17.3 1.8 0.0037 17.3 1.8 2.6 3 0 0 3 3 3 1 Coiled-coil domain containing 32 CENP-X PF09415.10 EAX84940.1 - 0.71 10.2 3.0 0.4 11.0 0.3 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF3839 PF12943.7 EAX84941.1 - 1.1e-157 522.7 12.8 1.4e-157 522.4 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX84942.1 - 0.048 13.6 8.4 0.067 13.2 8.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX84943.1 - 0.067 13.6 2.0 0.09 13.2 2.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX84946.1 - 2.2e-101 338.4 8.0 2.5e-101 338.2 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aldo_ket_red PF00248.21 EAX84947.1 - 1.4e-43 149.2 0.1 5.8e-43 147.2 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family RIC3 PF15361.6 EAX84948.1 - 0.04 14.3 1.6 0.041 14.3 1.6 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GPS2_interact PF15784.5 EAX84948.1 - 0.047 14.1 0.3 0.055 13.9 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX84949.1 - 6.4e-156 516.9 11.9 8.1e-156 516.6 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX84950.1 - 1.2e-22 79.8 0.3 2.3e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3781 PF12636.7 EAX84951.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX84953.1 - 2.4e-156 518.4 13.7 3e-156 518.0 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX84953.1 - 1 9.9 5.7 5 7.6 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX84954.1 - 0.00069 20.1 0.1 0.0014 19.2 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX84954.1 - 0.014 15.3 0.2 0.033 14.1 0.2 1.8 1 1 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX84954.1 - 0.018 14.6 0.9 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Gly-zipper_Omp PF13488.6 EAX84956.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX84956.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX84956.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX84957.1 - 3.1e-62 208.7 6.2 3.4e-62 208.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX84957.1 - 0.08 13.2 0.3 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX84959.1 - 2.6e-30 104.5 0.6 5.7e-30 103.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84959.1 - 0.013 16.1 0.7 0.03 14.9 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX84960.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84960.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84960.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84960.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84960.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84960.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84960.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84960.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX84960.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX84960.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84960.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84960.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84960.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX84961.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX84962.1 - 5.7e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX84963.1 - 5.9e-155 513.8 12.1 7.3e-155 513.5 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX84963.1 - 0.14 12.6 2.7 0.32 11.4 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX84963.1 - 0.28 11.7 4.9 4.9 7.7 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX84963.1 - 0.95 10.0 6.4 0.41 11.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX84963.1 - 2.3 8.6 4.8 11 6.4 0.0 3.3 2 2 1 3 3 3 0 Rx N-terminal domain Trypan_PARP PF05887.11 EAX84964.1 - 0.086 12.8 6.1 0.13 12.3 6.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84964.1 - 2 8.8 4.7 2.9 8.3 4.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HAD_2 PF13419.6 EAX84967.1 - 3.2e-23 82.7 0.0 4.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX84967.1 - 8.6e-11 42.5 0.2 9.3e-09 35.9 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX84967.1 - 0.00035 20.6 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAX84967.1 - 0.043 14.2 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAX84967.1 - 0.057 13.5 0.2 2.8 8.1 0.1 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mac PF12464.8 EAX84967.1 - 0.12 12.7 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Maltose acetyltransferase EGF_3 PF12947.7 EAX84968.1 - 0.027 14.7 9.5 0.027 14.7 9.5 3.9 4 0 0 4 4 4 0 EGF domain EGF PF00008.27 EAX84968.1 - 1.3 9.4 18.4 6.3 7.2 0.2 3.7 3 0 0 3 3 3 0 EGF-like domain cEGF PF12662.7 EAX84968.1 - 1.7 8.6 13.9 0.44 10.5 1.0 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 EAX84968.1 - 4.1 8.2 20.2 5.8 7.7 2.2 4.7 3 1 1 4 4 4 0 Human growth factor-like EGF TMEM154 PF15102.6 EAX84969.1 - 3.9 7.4 7.4 5.2 7.0 5.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family DUF3484 PF11983.8 EAX84969.1 - 6.5 8.0 7.4 13 7.0 7.4 1.5 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch malic PF00390.19 EAX84970.1 - 1.7e-30 106.2 0.0 1.2e-21 77.4 0.0 2.8 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 EAX84970.1 - 3.9e-30 105.0 6.0 6.3e-29 101.0 6.0 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 EAX84970.1 - 0.0058 16.4 0.4 0.0092 15.7 0.4 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EAX84970.1 - 0.0093 15.3 3.3 0.016 14.5 3.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EAX84970.1 - 0.027 13.8 0.6 0.069 12.5 0.5 1.7 1 1 0 1 1 1 0 ThiF family Ank_2 PF12796.7 EAX84971.1 - 3.8e-20 72.3 3.6 7.9e-13 48.8 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX84971.1 - 1.4e-14 54.2 0.5 4.7e-07 30.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX84971.1 - 1e-11 44.7 1.0 0.0026 18.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX84971.1 - 3.4e-11 43.2 0.3 8.2e-07 29.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX84971.1 - 2.9e-08 33.3 0.2 0.035 14.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat PrmC_N PF17827.1 EAX84971.1 - 0.016 15.8 0.1 6.7 7.4 0.0 2.1 2 0 0 2 2 2 0 PrmC N-terminal domain DNA_pol_B_2 PF03175.13 EAX84972.1 - 3.8e-15 55.7 0.8 4.6e-15 55.5 0.8 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 EAX84973.1 - 6.2e-09 35.2 1.1 1.2e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX84973.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX84973.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Fib_alpha PF08702.10 EAX84974.1 - 5.8e-05 23.3 34.9 0.00027 21.1 11.2 3.1 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EAX84974.1 - 9.8e-05 22.5 9.1 9.8e-05 22.5 9.1 3.1 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EAX84974.1 - 0.00012 22.6 25.1 0.3 11.8 0.1 5.9 2 1 4 6 6 6 2 SlyX Golgin_A5 PF09787.9 EAX84974.1 - 0.00018 21.1 40.2 0.0013 18.3 22.8 2.5 1 1 1 2 2 2 2 Golgin subfamily A member 5 ATG16 PF08614.11 EAX84974.1 - 0.0002 21.7 2.5 0.0002 21.7 2.5 3.5 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EAX84974.1 - 0.0017 18.1 24.9 0.0065 16.2 13.5 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF745) NPV_P10 PF05531.12 EAX84974.1 - 0.0081 16.6 9.5 0.51 10.9 0.1 3.9 3 1 0 3 3 3 1 Nucleopolyhedrovirus P10 protein HOOK PF05622.12 EAX84974.1 - 0.0085 14.3 32.9 0.0073 14.5 8.9 2.0 1 1 1 2 2 2 1 HOOK protein Csm1_N PF18504.1 EAX84974.1 - 0.0088 16.4 36.9 0.39 11.1 0.6 6.3 4 1 2 6 6 6 2 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 EAX84974.1 - 0.014 15.6 41.7 0.028 14.6 4.4 4.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding SesA PF17107.5 EAX84974.1 - 0.019 15.1 6.2 0.019 15.1 6.2 2.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_MLP1_2 PF07926.12 EAX84974.1 - 0.042 13.9 45.3 1.6 8.8 1.2 4.7 1 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EAX84974.1 - 0.12 12.8 27.1 0.84 10.1 2.2 5.6 2 1 4 6 6 6 0 Flagella accessory protein C (FlaC) CCDC144C PF14915.6 EAX84974.1 - 0.21 10.7 39.1 0.32 10.1 3.3 2.3 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region SKA1 PF07160.12 EAX84974.1 - 0.24 11.2 27.0 0.16 11.8 14.0 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 APG6_N PF17675.1 EAX84974.1 - 0.29 11.6 42.0 0.43 11.1 3.8 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EAX84974.1 - 0.32 9.8 43.1 0.64 8.8 11.5 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EAX84974.1 - 0.33 11.0 45.3 0.028 14.4 15.9 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 EAX84974.1 - 0.46 10.6 37.5 0.023 14.8 7.2 3.5 1 1 2 4 4 3 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 EAX84974.1 - 0.64 10.3 9.7 4.4 7.6 0.1 3.9 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) YscO PF07321.12 EAX84974.1 - 0.75 9.7 31.1 1 9.3 0.7 3.4 1 1 1 3 3 3 0 Type III secretion protein YscO Intimin_C PF07979.11 EAX84974.1 - 0.98 9.9 4.9 16 6.0 0.1 2.9 3 0 0 3 3 2 0 Intimin C-type lectin domain Tropomyosin_1 PF12718.7 EAX84974.1 - 0.99 9.6 43.5 0.031 14.4 11.1 4.2 1 1 2 3 3 2 0 Tropomyosin like PCRF PF03462.18 EAX84974.1 - 1.2 9.0 26.4 0.16 11.8 10.1 3.1 1 1 2 3 3 3 0 PCRF domain HALZ PF02183.18 EAX84974.1 - 1.3 9.4 17.2 0.087 13.1 1.4 4.6 5 0 0 5 5 3 0 Homeobox associated leucine zipper Fez1 PF06818.15 EAX84974.1 - 1.3 9.5 39.0 72 3.7 30.7 3.2 1 1 1 2 2 2 0 Fez1 Prefoldin_3 PF13758.6 EAX84974.1 - 1.5 9.0 18.6 2 8.5 6.0 3.8 2 2 2 4 4 4 0 Prefoldin subunit Bap31_Bap29_C PF18035.1 EAX84974.1 - 1.5 8.9 25.6 0.72 9.9 0.7 5.7 4 3 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain CALCOCO1 PF07888.11 EAX84974.1 - 1.8 7.4 36.3 0.25 10.1 19.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cnn_1N PF07989.11 EAX84974.1 - 1.9 8.7 32.4 0.085 13.0 5.4 4.8 2 2 1 3 3 2 0 Centrosomin N-terminal motif 1 Lebercilin PF15619.6 EAX84974.1 - 2 8.0 43.1 4.2 7.0 22.6 3.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 EAX84974.1 - 2.1 8.1 36.7 0.15 11.8 18.9 2.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 EAX84974.1 - 2.3 7.5 40.0 0.39 10.1 11.9 3.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding FlgN PF05130.12 EAX84974.1 - 3.1 8.3 29.0 1.8 9.1 0.9 3.5 1 1 1 3 3 3 0 FlgN protein KASH_CCD PF14662.6 EAX84974.1 - 3.4 7.5 41.4 0.19 11.6 18.1 3.8 1 1 1 2 2 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 EAX84974.1 - 3.5 8.3 31.6 0.34 11.6 4.5 4.1 1 1 2 3 3 2 0 Initiation control protein YabA MscS_porin PF12795.7 EAX84974.1 - 3.5 7.1 37.3 1.6 8.2 9.2 3.6 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 EAX84974.1 - 3.7 7.6 20.4 1 9.4 1.4 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EAX84974.1 - 3.8 6.8 20.9 1.9e+03 -2.1 20.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Leu_zip PF15294.6 EAX84974.1 - 4 6.9 31.3 1.4 8.4 11.9 2.5 1 1 1 2 2 2 0 Leucine zipper Lipoprotein_6 PF01441.19 EAX84974.1 - 4.1 7.4 8.5 11 6.0 1.2 2.5 1 1 1 2 2 2 0 Lipoprotein Rootletin PF15035.6 EAX84974.1 - 4.2 7.3 34.8 5.6 6.9 10.1 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spectrin PF00435.21 EAX84974.1 - 5.4 7.6 24.8 0.57 10.7 0.4 4.2 1 1 1 3 3 3 0 Spectrin repeat ADIP PF11559.8 EAX84974.1 - 5.7 7.0 42.8 19 5.3 6.1 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 EAX84974.1 - 6.3 6.7 35.2 0.17 11.8 5.4 4.1 1 1 3 5 5 5 0 Sec34-like family LPP PF04728.13 EAX84974.1 - 7.1 7.1 21.0 2.3 8.7 0.5 5.4 6 1 0 6 6 6 0 Lipoprotein leucine-zipper Atg14 PF10186.9 EAX84974.1 - 8.8 5.3 40.6 4.9 6.1 31.5 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SpecificRecomb PF10136.9 EAX84974.1 - 9.8 4.3 11.6 1.4 7.1 7.4 1.6 1 1 0 1 1 1 0 Site-specific recombinase Tropomyosin PF00261.20 EAX84974.1 - 9.8 5.5 37.0 3.5 6.9 12.7 3.8 1 1 2 3 3 3 0 Tropomyosin T5orf172 PF10544.9 EAX84975.1 - 0.0014 19.2 0.2 0.0041 17.6 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX84975.1 - 0.002 17.7 0.8 0.11 12.0 0.3 2.1 2 0 0 2 2 2 2 Legume lectin domain KilA-N PF04383.13 EAX84975.1 - 0.011 15.5 0.0 0.034 14.0 0.0 1.9 2 0 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX84976.1 - 8.1e-78 261.2 10.1 1.1e-77 260.8 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84976.1 - 0.058 13.6 0.2 0.14 12.4 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX84976.1 - 0.075 12.9 1.7 0.27 11.1 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase LD_cluster2 PF18163.1 EAX84976.1 - 0.12 11.9 0.5 1.5 8.3 0.0 2.4 2 1 0 3 3 3 0 SLOG cluster2 PapD_N PF00345.20 EAX84977.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX84977.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4108 PF13390.6 EAX84979.1 - 3e-58 195.8 5.2 3.3e-58 195.7 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX84979.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX84980.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX84980.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX84980.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX84980.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX84980.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX84980.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX84980.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX84980.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX84980.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX84980.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX84980.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX84980.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX84981.1 - 9.4e-42 141.4 0.2 2.2e-41 140.2 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX84981.1 - 0.015 15.9 0.1 0.039 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX84982.1 - 6e-16 58.6 3.3 9.6e-16 58.0 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX84982.1 - 0.037 14.3 0.4 0.11 12.8 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX84982.1 - 0.14 12.7 1.6 0.49 10.9 1.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB PTR PF12789.7 EAX84983.1 - 2.3e-57 190.9 40.4 2.1e-32 111.0 18.9 4.5 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX84983.1 - 0.057 13.2 0.9 0.098 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) RICTOR_V PF14668.6 EAX84985.1 - 0.014 15.6 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Pox_polyA_pol_N PF12630.7 EAX84985.1 - 0.025 14.9 3.4 0.36 11.2 0.0 3.2 2 1 1 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Arm_2 PF04826.13 EAX84985.1 - 0.053 13.0 8.5 0.067 12.6 0.0 2.8 1 1 1 3 3 3 0 Armadillo-like PIEZO PF15917.5 EAX84985.1 - 0.054 13.0 1.6 0.1 12.0 1.6 1.4 1 0 0 1 1 1 0 Piezo DRY_EERY PF09750.9 EAX84985.1 - 0.73 10.1 3.8 1.3 9.3 3.8 1.4 1 0 0 1 1 1 0 Alternative splicing regulator IFP_35_N PF07334.13 EAX84985.1 - 0.9 9.7 5.7 14 5.9 4.6 2.5 1 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus T5orf172 PF10544.9 EAX84987.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX84988.1 - 5e-147 487.8 11.2 6.3e-147 487.5 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX84988.1 - 0.1 12.4 0.5 0.28 11.0 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX84988.1 - 0.63 10.5 3.9 0.7 10.4 0.8 2.7 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX84989.1 - 2.7e-09 36.4 0.8 5.4e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX84989.1 - 0.089 11.5 2.9 0.79 8.4 2.9 2.1 1 1 0 1 1 1 0 DNA polymerase family B Lac_bphage_repr PF06543.12 EAX84989.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX84990.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX84990.1 - 0.06 13.3 0.5 0.088 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX84991.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX84991.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX84992.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta KHA PF11834.8 EAX84993.1 - 0.16 12.1 1.7 0.33 11.1 1.0 2.0 1 1 1 2 2 2 0 KHA, dimerisation domain of potassium ion channel DUF4295 PF14128.6 EAX84994.1 - 0.061 13.1 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) TIG PF01833.24 EAX84995.1 - 0.00012 22.1 1.0 0.00029 20.9 0.5 2.0 1 1 1 2 2 2 1 IPT/TIG domain TIG_plexin PF17960.1 EAX84995.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 1.8 2 0 0 2 2 2 1 TIG domain DUF3839 PF12943.7 EAX84996.1 - 2.2e-117 390.8 11.9 2.8e-117 390.4 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX84996.1 - 0.03 14.6 0.1 0.083 13.1 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 KELK PF15796.5 EAX84996.1 - 0.081 13.4 1.3 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX84996.1 - 0.089 12.7 2.0 0.37 10.6 1.8 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase KilA-N PF04383.13 EAX84997.1 - 2.8e-22 78.7 0.1 4.1e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX84997.1 - 0.079 12.9 0.4 0.088 12.8 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Trypan_PARP PF05887.11 EAX84998.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX84998.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX84999.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX84999.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX85000.1 - 1.7e-155 515.5 14.0 2.2e-155 515.2 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX85000.1 - 0.095 13.0 0.3 1.5 9.1 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX85000.1 - 0.33 11.4 5.7 2.1 8.9 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX85001.1 - 0.00012 22.6 0.3 0.00028 21.4 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85001.1 - 0.0074 16.1 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Xpo1 PF08389.12 EAX85002.1 - 0.025 14.7 1.0 0.056 13.5 1.0 1.6 1 0 0 1 1 1 0 Exportin 1-like protein UvsY PF11056.8 EAX85002.1 - 0.073 13.4 1.7 1 9.7 0.5 2.4 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DUF3361 PF11841.8 EAX85002.1 - 0.14 12.1 3.2 0.14 12.1 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Ribosomal_S4e PF00900.20 EAX85004.1 - 3e-26 91.1 0.1 1e-25 89.4 0.1 2.0 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 EAX85004.1 - 5.4e-16 58.4 4.9 1.1e-15 57.5 4.9 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 EAX85004.1 - 3.2e-14 52.3 0.0 7.1e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 EAX85004.1 - 6.5e-08 32.2 0.0 1.9e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EAX85004.1 - 0.00011 22.0 0.8 0.00011 22.0 0.8 3.2 3 1 1 4 4 4 1 KOW motif Ank_2 PF12796.7 EAX85005.1 - 1e-21 77.3 0.1 1.3e-08 35.3 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85005.1 - 2.4e-13 48.9 1.6 0.00049 20.3 0.0 6.5 6 1 1 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 EAX85005.1 - 3.6e-11 43.4 0.2 8.6e-05 23.0 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX85005.1 - 6.3e-11 42.3 0.0 2.2e-06 27.8 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX85005.1 - 1e-09 38.4 0.0 4.9e-05 23.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF3839 PF12943.7 EAX85006.1 - 3.6e-157 521.0 12.8 4.6e-157 520.7 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85006.1 - 0.054 13.9 1.5 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Fez1 Z1 PF10593.9 EAX85006.1 - 0.28 10.7 3.8 0.32 10.5 0.1 2.3 1 1 1 2 2 2 0 Z1 domain NTP_transf_6 PF06042.11 EAX85006.1 - 0.38 10.6 2.3 0.71 9.7 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX85006.1 - 0.48 10.9 4.5 7.5 7.1 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85006.1 - 0.9 10.1 5.3 0.43 11.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX85006.1 - 2.4 8.5 6.2 13 6.2 0.1 3.6 4 1 1 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX85007.1 - 1.1e-06 29.1 0.1 2.8e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85007.1 - 0.0047 16.8 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain Ank_2 PF12796.7 EAX85008.1 - 1.1e-06 29.2 0.0 1.2e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85008.1 - 1.9e-05 25.1 0.0 2.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX85008.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85008.1 - 0.0051 17.2 0.0 0.058 14.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX85008.1 - 0.078 13.5 0.0 5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat KilA-N PF04383.13 EAX85011.1 - 1.9e-44 150.1 1.5 2.4e-44 149.8 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85011.1 - 0.021 15.0 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX85012.1 - 1.4e-155 515.9 13.1 1.7e-155 515.5 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85012.1 - 0.11 13.0 0.2 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85012.1 - 2.5 8.6 6.2 5.3 7.6 0.3 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX85013.1 - 6.8e-38 128.5 25.8 4.5e-31 106.7 12.8 4.2 4 2 1 5 5 5 2 Phage tail repeat like DUF2357 PF09823.9 EAX85013.1 - 0.011 15.0 3.5 0.018 14.3 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF4116 PF13475.6 EAX85013.1 - 0.022 14.5 1.0 0.045 13.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX85013.1 - 7.9 7.2 8.4 9.7 6.9 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) T5orf172 PF10544.9 EAX85014.1 - 1.3e-05 25.7 0.2 2.8e-05 24.6 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX85015.1 - 1.4e-156 519.1 13.7 1.8e-156 518.7 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85015.1 - 0.41 11.1 5.5 2.1 8.8 0.7 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85015.1 - 0.79 10.3 5.8 2.2 8.9 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX85015.1 - 1.8 8.9 6.2 12 6.3 0.0 3.8 3 1 1 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX85016.1 - 7.8e-45 151.3 0.6 1.6e-44 150.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85016.1 - 0.033 14.4 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) TMEM132D_C PF15706.5 EAX85017.1 - 0.00088 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Syndecan PF01034.20 EAX85017.1 - 0.011 15.6 0.8 0.017 15.0 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.6 EAX85017.1 - 0.11 12.9 0.3 0.15 12.5 0.3 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Col_cuticle_N PF01484.17 EAX85017.1 - 0.15 12.1 1.3 0.28 11.3 1.3 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain LRR_5 PF13306.6 EAX85018.1 - 5.3e-111 365.9 72.5 4.5e-23 81.6 20.2 8.3 1 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85018.1 - 1.7e-10 40.5 8.0 6.2 6.7 0.0 11.9 7 3 8 15 15 15 4 Leucine rich repeat CTV_P13 PF06922.11 EAX85018.1 - 0.017 15.2 1.0 0.45 10.6 0.4 2.7 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein FLgD_tudor PF13861.6 EAX85018.1 - 0.15 12.3 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 FlgD Tudor-like domain Pentapeptide_3 PF13576.6 EAX85018.1 - 2.4 8.4 15.8 23 5.2 0.3 6.5 7 1 0 7 7 7 0 Pentapeptide repeats (9 copies) Pox_A32 PF04665.12 EAX85019.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85019.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85019.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85019.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85019.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85019.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85019.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85019.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85019.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85019.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85019.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85019.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX85020.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX85020.1 - 10 6.1 6.6 20 5.2 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX85021.1 - 1.2e-57 193.9 6.4 1.3e-57 193.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX85022.1 - 0.00012 22.5 3.5 0.00061 20.2 3.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX85022.1 - 0.024 15.2 0.1 0.052 14.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX85022.1 - 0.034 13.2 1.2 0.049 12.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX85022.1 - 0.06 13.3 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DDR PF08841.10 EAX85023.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85023.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX85024.1 - 0.0043 17.0 6.4 0.0064 16.5 6.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Myb_DNA-bind_6 PF13921.6 EAX85025.1 - 2e-28 98.4 3.2 1.6e-17 63.4 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX85025.1 - 3.7e-27 94.2 0.5 9.5e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85025.1 - 0.00012 22.1 0.1 0.074 13.1 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX85025.1 - 0.0033 17.6 1.1 1.6 8.9 0.1 2.8 2 1 1 3 3 3 2 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAX85025.1 - 0.0045 17.2 0.2 0.45 10.7 0.0 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX85025.1 - 0.022 15.1 8.4 7.4 7.0 0.1 3.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX85025.1 - 0.11 12.4 2.0 7.5 6.5 0.3 2.3 1 1 1 2 2 2 0 Myb DNA-binding like MIS13 PF08202.11 EAX85026.1 - 0.02 14.2 1.2 0.024 14.0 1.2 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family zf-C2HE PF16278.5 EAX85026.1 - 0.065 13.7 3.2 1.9 9.0 0.0 3.1 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3839 PF12943.7 EAX85029.1 - 2.4e-155 515.0 13.5 3.1e-155 514.7 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX85029.1 - 0.86 10.2 4.5 1.3 9.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85029.1 - 2.5 8.6 7.0 2.2 8.8 0.5 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3781 PF12636.7 EAX85031.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX85032.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85032.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain M60-like_N PF17291.2 EAX85034.1 - 7.9e-10 38.6 0.0 2.5e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 EAX85034.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Trans_reg_C PF00486.28 EAX85034.1 - 0.2 11.8 0.0 0.5 10.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Pkinase PF00069.25 EAX85035.1 - 9.6e-74 248.1 0.2 1.7e-73 247.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85035.1 - 2.9e-43 148.0 0.0 4.4e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85035.1 - 0.00013 21.4 0.0 0.00046 19.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX85035.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX85035.1 - 0.00033 20.1 0.5 0.00057 19.3 0.5 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX85035.1 - 0.0011 18.0 0.5 0.002 17.1 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EAX85035.1 - 0.0015 18.2 1.0 0.0023 17.5 0.4 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAX85035.1 - 0.044 13.4 0.2 3.2 7.3 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX85035.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3781 PF12636.7 EAX85036.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX85037.1 - 0.096 11.7 0.1 0.097 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85037.1 - 0.12 12.8 1.4 0.18 12.2 1.4 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX85038.1 - 1.3e-153 509.4 13.8 1.6e-153 509.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX85038.1 - 0.19 12.0 2.4 0.88 9.9 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX85038.1 - 0.65 10.5 7.4 3 8.4 1.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX85041.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85043.1 - 2.6e-152 505.1 12.5 3.2e-152 504.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX85043.1 - 0.14 13.1 1.6 0.36 11.8 0.4 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Glu-tRNAGln PF02686.15 EAX85043.1 - 0.32 11.3 1.6 0.68 10.3 0.2 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX85043.1 - 1.9 9.1 5.7 1.4 9.5 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX85044.1 - 3.6e-30 105.2 11.0 1.6e-29 103.2 11.0 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAX85045.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85045.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85046.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85046.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX85047.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85047.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Shisa PF13908.6 EAX85049.1 - 0.00086 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 EAX85049.1 - 0.035 14.3 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A MBDa PF16564.5 EAX85049.1 - 0.63 10.2 2.3 1.4 9.1 0.5 2.3 2 0 0 2 2 2 0 p55-binding region of Methyl-CpG-binding domain proteins MBD CYYR1 PF10873.8 EAX85049.1 - 1 9.8 6.3 0.2 12.1 0.7 2.7 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF4625 PF15418.6 EAX85050.1 - 1.5e-05 25.3 13.0 0.089 13.0 0.1 6.5 6 0 0 6 6 6 1 Domain of unknown function (DUF4625) Herpes_gE PF02480.16 EAX85050.1 - 0.00011 21.1 0.3 0.071 11.9 0.1 2.8 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 EAX85050.1 - 0.0047 16.8 0.6 0.0047 16.8 0.6 2.4 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 EAX85050.1 - 0.011 16.6 0.5 0.075 13.9 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0239 PF06783.11 EAX85050.1 - 0.034 14.3 0.2 0.11 12.7 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) Amnionless PF14828.6 EAX85050.1 - 0.038 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 EAX85050.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Peptidase_M56 PF05569.11 EAX85050.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM51 PF15345.6 EAX85050.1 - 0.096 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4577 PF15145.6 EAX85050.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) PBP_N PF17093.5 EAX85050.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Hydrolase_6 PF13344.6 EAX85051.1 - 3.5e-22 78.4 0.0 6.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX85051.1 - 9.4e-20 70.5 0.0 2.1e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EAX85051.1 - 1.4e-08 35.0 0.0 0.00096 19.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX85051.1 - 6.7e-07 29.8 0.0 8.6e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EAX85051.1 - 0.029 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase CH PF00307.31 EAX85052.1 - 0.1 12.8 0.0 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF4108 PF13390.6 EAX85054.1 - 3.5e-61 205.3 7.8 3.9e-61 205.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4457 PF14652.6 EAX85056.1 - 0.091 12.0 0.1 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) SpoVAE PF14097.6 EAX85056.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AE1 HALZ PF02183.18 EAX85057.1 - 0.0087 16.3 0.3 0.0087 16.3 0.3 5.1 5 0 0 5 5 5 2 Homeobox associated leucine zipper YabA PF06156.13 EAX85057.1 - 0.05 14.3 2.9 0.05 14.3 2.9 5.7 1 1 4 5 5 5 0 Initiation control protein YabA Filament PF00038.21 EAX85057.1 - 0.42 10.2 63.5 2 7.9 22.2 2.4 1 1 2 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 EAX85057.1 - 4 4.8 54.9 0.18 9.3 31.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) XhlA PF10779.9 EAX85058.1 - 0.012 15.8 13.1 0.1 12.8 0.7 3.9 3 0 0 3 3 3 0 Haemolysin XhlA UPF0242 PF06785.11 EAX85058.1 - 0.057 13.5 42.9 0.044 13.9 13.3 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus MerR-DNA-bind PF09278.11 EAX85058.1 - 0.1 13.2 3.7 0.4 11.3 0.5 2.8 2 1 1 3 3 3 0 MerR, DNA binding ABC_tran_CTD PF16326.5 EAX85058.1 - 0.12 12.7 0.1 0.12 12.7 0.1 5.6 4 2 1 5 5 5 0 ABC transporter C-terminal domain HALZ PF02183.18 EAX85058.1 - 2.9 8.2 7.7 0.29 11.4 1.9 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3839 PF12943.7 EAX85060.1 - 4e-154 511.1 12.2 5.1e-154 510.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85060.1 - 0.17 11.7 1.3 0.57 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX85061.1 - 5.2e-44 148.7 0.7 1e-43 147.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85061.1 - 0.013 16.1 0.2 0.043 14.5 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family HD PF01966.22 EAX85062.1 - 6.3e-10 39.3 0.1 1.2e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EAX85062.1 - 0.063 13.0 0.3 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Gly_rich PF12810.7 EAX85063.1 - 7.9e-60 202.8 33.0 9.5e-60 202.5 33.0 1.0 1 0 0 1 1 1 1 Glycine rich protein PQ-loop PF04193.14 EAX85064.1 - 3.7e-06 26.6 18.6 8.9e-06 25.4 0.6 3.9 4 0 0 4 4 4 2 PQ loop repeat Sarcolipin PF05366.11 EAX85064.1 - 2.8 7.7 11.4 23 4.8 7.6 2.8 2 0 0 2 2 2 0 Sarcolipin Syndecan PF01034.20 EAX85064.1 - 5.8 6.9 6.0 25 4.9 0.5 3.1 3 0 0 3 3 3 0 Syndecan domain Pox_A32 PF04665.12 EAX85065.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85065.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85065.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85065.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX85066.1 - 4.1e-43 145.8 1.1 6.2e-43 145.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85066.1 - 0.025 15.2 0.2 0.091 13.4 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX85067.1 - 5e-145 481.3 15.0 6.2e-145 481.0 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85067.1 - 0.062 13.2 1.2 0.21 11.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX85067.1 - 5.2 7.6 7.3 2.2 8.8 0.8 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85068.1 - 1.8e-142 472.9 14.6 2.5e-142 472.5 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85068.1 - 0.0056 17.1 1.3 0.029 14.8 0.2 2.0 2 0 0 2 2 2 1 Fez1 DUF848 PF05852.11 EAX85068.1 - 0.18 11.9 2.8 0.95 9.6 0.2 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) KELK PF15796.5 EAX85068.1 - 0.38 11.2 5.1 3.4 8.2 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85068.1 - 1.7 9.2 6.1 0.9 10.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX85069.1 - 1.4e-40 137.6 2.8 1.5e-40 137.5 0.9 2.1 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85069.1 - 0.0046 17.5 0.3 0.017 15.7 0.0 2.1 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX85070.1 - 2.7e-07 30.3 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85070.1 - 0.0048 16.6 0.1 0.0064 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX85070.1 - 0.048 13.1 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX85070.1 - 0.057 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85070.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF3839 PF12943.7 EAX85071.1 - 9.3e-156 516.4 12.1 1.2e-155 516.1 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX85071.1 - 0.37 11.1 2.0 0.58 10.5 0.2 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF4107 PF13389.6 EAX85073.1 - 3.8e-72 241.7 3.6 5e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX85075.1 - 2.8 7.9 12.0 3 7.8 12.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX85076.1 - 0.041 14.3 0.5 0.049 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PWI PF01480.17 EAX85079.1 - 0.07 13.5 0.2 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 PWI domain DNA_pol_B_2 PF03175.13 EAX85081.1 - 4.5e-37 128.0 15.4 1.6e-36 126.2 15.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Collagen PF01391.18 EAX85081.1 - 4.4e-05 23.1 10.3 7.1e-05 22.5 10.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX85081.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus JMY PF15871.5 EAX85081.1 - 0.098 11.9 0.4 0.21 10.9 0.4 1.5 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX85081.1 - 0.11 12.6 0.9 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF2939 PF11159.8 EAX85083.1 - 0.03 14.7 0.5 0.037 14.4 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX85083.1 - 1.2 9.1 5.8 1.3 9.0 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX85084.1 - 8.2e-150 496.9 15.3 1e-149 496.6 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85084.1 - 0.072 12.9 1.6 0.17 11.7 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KilA-N PF04383.13 EAX85085.1 - 3.1e-41 139.7 0.2 3.1e-41 139.7 0.2 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85085.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX85085.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX85085.1 - 0.15 10.6 0.1 0.22 10.0 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX85086.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85086.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85086.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85086.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85086.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85086.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85086.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85086.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85086.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85086.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85086.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85086.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX85087.1 - 2.4e-54 184.3 3.9 2.8e-54 184.2 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX85087.1 - 0.011 15.3 0.4 0.012 15.1 0.4 1.0 1 0 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX85087.1 - 0.15 12.5 2.1 0.39 11.2 2.1 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85089.1 - 7.1e-137 454.6 8.0 8.4e-137 454.3 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85089.1 - 0.44 11.0 7.5 2.3 8.7 0.8 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85089.1 - 1.6 9.1 6.1 5.9 7.3 0.1 3.1 2 1 1 3 3 3 0 Tup N-terminal LRR_5 PF13306.6 EAX85090.1 - 4e-118 388.9 114.3 3.7e-22 78.7 12.7 8.9 1 1 8 9 9 9 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85090.1 - 5.8e-30 102.9 16.8 0.00069 19.3 0.0 12.1 10 3 3 13 13 13 8 Leucine rich repeat LRR_4 PF12799.7 EAX85090.1 - 0.0001 22.6 20.2 5.1 7.7 0.0 8.9 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) Pox_A32 PF04665.12 EAX85091.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX85091.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PSP PF04046.16 EAX85092.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85093.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat BspA_v PF18220.1 EAX85094.1 - 1.6 8.8 5.7 3.9 7.6 0.8 2.3 2 1 0 2 2 2 0 Adhesin BspA variable domain Spc7_N PF15402.6 EAX85095.1 - 0.02 13.2 5.4 0.023 13.0 5.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pox_A32 PF04665.12 EAX85098.1 - 4.9e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX85098.1 - 0.0057 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX85098.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX85098.1 - 0.077 13.3 1.7 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4107 PF13389.6 EAX85099.1 - 9e-73 243.8 3.9 1.2e-72 243.4 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Peptidase_S8 PF00082.22 EAX85101.1 - 2.6e-16 59.8 0.1 3.7e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Sulf_coat_C PF12193.8 EAX85101.1 - 0.0089 16.1 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 Sulfolobus virus coat protein C terminal EGF PF00008.27 EAX85101.1 - 0.13 12.6 9.1 0.26 11.6 9.1 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 EAX85101.1 - 0.74 10.2 17.4 0.056 13.8 12.5 1.7 2 0 0 2 2 2 0 EGF-like domain Gly_rich PF12810.7 EAX85102.1 - 2.2e-40 139.1 65.0 2.7e-40 138.8 65.0 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4107 PF13389.6 EAX85104.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX85106.1 - 0.096 13.2 1.6 0.12 12.9 0.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX85107.1 - 2.9e-18 65.7 26.0 1.6e-11 44.1 4.1 5.1 6 0 0 6 6 6 2 Phage tail repeat like NPV_P10 PF05531.12 EAX85107.1 - 0.0081 16.6 2.7 14 6.2 0.0 3.5 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF4943 PF16301.5 EAX85107.1 - 0.023 14.7 4.2 3.3 7.7 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4943) EMP24_GP25L PF01105.24 EAX85107.1 - 0.59 10.1 3.7 5.4 6.9 3.6 2.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YmaF PF12788.7 EAX85107.1 - 1.4 9.5 0.0 1.4 9.5 0.0 4.0 3 1 0 3 3 3 0 YmaF family CppA_C PF14507.6 EAX85107.1 - 9.9 7.0 7.7 13 6.5 0.2 3.4 4 0 0 4 4 4 0 CppA C-terminal KilA-N PF04383.13 EAX85108.1 - 3.8e-22 78.3 0.1 7.1e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX85108.1 - 0.21 11.0 1.5 0.68 9.3 0.6 2.1 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain T5orf172 PF10544.9 EAX85109.1 - 1.1e-06 29.1 0.2 2.3e-06 28.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85110.1 - 1.7e-42 143.8 0.7 3.6e-42 142.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85110.1 - 0.01 16.0 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX85111.1 - 5.1e-07 29.4 2.1 5.1e-07 29.4 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85111.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85111.1 - 3.7e-05 23.5 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85111.1 - 0.00012 22.1 3.0 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85111.1 - 0.00062 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85111.1 - 0.0013 18.6 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85111.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85111.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX85111.1 - 0.075 12.6 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85111.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85111.1 - 0.094 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85111.1 - 0.74 10.1 4.2 17 5.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX85112.1 - 1.7 8.6 3.7 3.6 7.5 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX85113.1 - 2.8e-64 215.4 6.3 3.1e-64 215.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85113.1 - 0.12 12.6 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide KilA-N PF04383.13 EAX85114.1 - 1.6e-42 143.9 0.3 2.2e-42 143.5 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX85115.1 - 1.9e-06 28.3 0.1 5.3e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX85115.1 - 0.017 14.7 0.6 0.35 10.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX85116.1 - 3.2e-119 396.8 12.4 4.1e-119 396.4 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85116.1 - 0.026 15.0 3.0 1.8 9.0 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX85116.1 - 0.18 11.6 1.9 0.47 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PRD PF00874.20 EAX85116.1 - 0.41 11.0 3.3 0.77 10.1 0.1 2.9 3 1 1 4 4 4 0 PRD domain PTR PF12789.7 EAX85118.1 - 2.1e-126 412.0 99.3 3.7e-32 110.2 15.8 5.5 3 2 4 7 7 7 5 Phage tail repeat like DUF4116 PF13475.6 EAX85118.1 - 0.053 13.2 0.9 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX85118.1 - 1.2 9.6 9.1 77 3.7 0.1 5.2 1 1 5 6 6 6 0 TFIIH p62 subunit, N-terminal domain DUF1493 PF07377.12 EAX85119.1 - 0.054 14.0 0.4 0.16 12.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX85120.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85121.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX85122.1 - 1.1e-142 473.6 10.4 1.4e-142 473.3 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85122.1 - 0.096 13.1 0.3 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85122.1 - 0.33 11.5 4.4 3.8 8.0 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85122.1 - 2.6 8.4 6.3 13 6.1 0.0 3.5 3 1 1 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX85123.1 - 5.7e-07 30.0 0.3 1.5e-06 28.7 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85123.1 - 0.0076 16.1 0.1 0.064 13.1 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX85124.1 - 1.5e-27 95.6 1.2 9e-26 89.9 1.2 2.2 1 1 0 1 1 1 1 KilA-N domain Connexin PF00029.19 EAX85124.1 - 0.47 10.2 1.4 1 9.0 1.4 1.6 1 1 0 1 1 1 0 Connexin PTR PF12789.7 EAX85127.1 - 1.5e-151 492.6 105.4 8e-31 105.9 13.4 7.6 2 2 5 7 7 7 6 Phage tail repeat like DUF4116 PF13475.6 EAX85127.1 - 0.036 13.8 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX85127.1 - 0.26 11.0 9.0 15 5.3 1.8 4.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) Peptidase_C39_2 PF13529.6 EAX85127.1 - 5.8 7.5 9.0 5 7.7 2.1 3.5 1 1 1 3 3 3 0 Peptidase_C39 like family TMP PF05017.14 EAX85130.1 - 0.15 12.7 5.5 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX85130.1 - 9.8 6.2 9.0 10 6.1 9.0 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX85131.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Gly-zipper_Omp PF13488.6 EAX85132.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX85132.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX85132.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX85132.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX85132.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PARP PF00644.20 EAX85134.1 - 1.7e-13 50.6 0.7 2.9e-13 49.9 0.7 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EAX85134.1 - 4.6e-06 26.8 0.1 0.00012 22.2 0.1 2.8 2 0 0 2 2 2 1 ARTD15 N-terminal domain UBA PF00627.31 EAX85134.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain UBA_4 PF14555.6 EAX85134.1 - 0.022 14.6 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 UBA-like domain RuvA_C PF07499.13 EAX85134.1 - 0.08 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain zf-P11 PF03854.14 EAX85134.1 - 0.17 11.5 3.3 0.56 9.9 3.3 1.8 1 0 0 1 1 1 0 P-11 zinc finger Chromo PF00385.24 EAX85135.1 - 0.062 13.2 2.2 0.12 12.3 2.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_MLP1_2 PF07926.12 EAX85136.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX85136.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX85136.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4795 PF16043.5 EAX85137.1 - 0.0015 18.2 13.2 0.26 10.9 5.4 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) AlkA_N PF06029.11 EAX85137.1 - 0.033 14.5 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 AlkA N-terminal domain DUF1947 PF09183.10 EAX85137.1 - 0.22 11.8 6.7 3.1 8.2 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) TetR_C_26 PF17934.1 EAX85137.1 - 0.31 11.4 5.9 3.9 7.9 0.5 3.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4902 PF16245.5 EAX85137.1 - 0.37 10.7 1.5 15 5.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4902) Pkinase PF00069.25 EAX85139.1 - 8.6e-58 195.8 0.6 1.4e-57 195.1 0.5 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85139.1 - 4.8e-40 137.5 0.0 5.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85139.1 - 3.2e-07 29.9 0.0 2.6e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EAX85139.1 - 0.00028 20.3 0.5 0.00052 19.4 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX85139.1 - 0.00049 19.0 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX85139.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX85139.1 - 0.0056 16.3 0.1 0.0084 15.7 0.1 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 EAX85140.1 - 3.2e-59 200.4 0.5 4.1e-59 200.1 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85140.1 - 9e-42 143.1 0.1 1.1e-41 142.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX85140.1 - 1.4e-05 25.2 0.0 6.6e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX85140.1 - 0.00034 20.0 0.0 0.00077 18.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX85140.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4949 PF16307.5 EAX85140.1 - 0.024 14.7 0.1 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4949) PglD_N PF17836.1 EAX85140.1 - 0.091 13.4 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain PTR PF12789.7 EAX85141.1 - 1.1e-51 172.7 33.3 7.6e-32 109.2 14.3 5.4 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX85141.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4108 PF13390.6 EAX85142.1 - 4.2e-59 198.6 4.4 4.6e-59 198.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX85142.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX85144.1 - 4.7e-06 26.2 2.1 4.7e-06 26.2 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EAX85144.1 - 9.4e-05 22.5 2.9 0.0002 21.4 2.2 1.8 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX85144.1 - 0.00037 20.8 0.1 0.0011 19.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85144.1 - 0.0005 19.8 0.2 0.45 10.2 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX85144.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85144.1 - 0.0017 18.2 0.5 0.004 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85144.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 EAX85144.1 - 0.019 14.6 0.4 0.11 12.1 0.5 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX85144.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX85144.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX85144.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX85144.1 - 0.26 11.6 4.5 5 7.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX85145.1 - 2e-39 133.9 0.6 3.6e-39 133.1 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85145.1 - 0.081 13.1 2.4 0.11 12.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX85146.1 - 1.2e-153 509.5 11.8 1.5e-153 509.2 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85146.1 - 0.033 14.6 2.7 0.095 13.1 0.5 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX85146.1 - 1.3 9.6 6.9 0.3 11.6 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85146.1 - 1.3 9.5 6.5 4.4 7.8 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX85146.1 - 3.7 7.9 7.1 0.91 9.9 0.2 3.1 3 1 1 4 4 4 0 PRD domain DUF3781 PF12636.7 EAX85147.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX85148.1 - 6.6e-133 441.6 13.1 2e-132 440.0 13.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85148.1 - 0.095 13.1 3.1 0.11 12.9 0.7 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX85148.1 - 0.13 12.7 0.5 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85148.1 - 0.21 12.1 8.3 0.77 10.3 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX85149.1 - 7.5e-74 247.3 4.5 9e-74 247.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85149.1 - 0.033 14.6 0.3 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX85149.1 - 0.13 10.6 1.2 0.18 10.2 1.2 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX85150.1 - 0.0095 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase T5orf172 PF10544.9 EAX85151.1 - 9.1e-05 22.9 0.1 0.00077 20.0 0.1 2.1 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX85151.1 - 0.044 13.3 0.6 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Legume lectin domain Rer1 PF03248.13 EAX85152.1 - 0.024 14.4 0.8 0.044 13.5 0.8 1.4 1 0 0 1 1 1 0 Rer1 family TMEM156 PF15106.6 EAX85152.1 - 1.1 8.7 6.3 4.8 6.6 6.8 1.7 1 1 1 2 2 2 0 TMEM156 protein family Orf78 PF06024.12 EAX85153.1 - 0.0018 18.5 12.0 0.02 15.2 5.3 2.5 2 0 0 2 2 2 2 Orf78 (ac78) SMP_2 PF10144.9 EAX85153.1 - 0.75 9.4 4.7 0.11 12.2 0.5 1.7 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Vpu PF00558.19 EAX85153.1 - 0.89 9.4 7.9 0.32 10.8 1.8 2.6 2 1 0 2 2 2 0 Vpu protein UCH PF00443.29 EAX85156.1 - 0.00042 19.9 1.6 0.011 15.3 1.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fungal_lectin_2 PF18647.1 EAX85156.1 - 0.031 14.7 0.8 0.056 13.9 0.3 1.8 1 1 1 2 2 2 0 Alpha-galactosyl-binding fungal lectin DUF3839 PF12943.7 EAX85157.1 - 1.2e-80 270.5 9.9 1.5e-80 270.1 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX85157.1 - 0.048 13.9 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF29 GalP_UDP_transf PF01087.22 EAX85157.1 - 0.21 12.0 1.7 1.4 9.3 0.9 2.0 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain NTP_transf_6 PF06042.11 EAX85157.1 - 0.3 10.9 1.9 0.99 9.3 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase T5orf172 PF10544.9 EAX85158.1 - 0.00033 21.1 0.1 0.00078 20.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX85158.1 - 0.12 11.9 0.3 1.9 7.9 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Pkinase PF00069.25 EAX85159.1 - 2.9e-38 131.8 1.4 3.5e-38 131.5 1.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85159.1 - 5.9e-18 65.1 0.4 7.6e-18 64.7 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85159.1 - 3.4e-07 29.9 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3839 PF12943.7 EAX85161.1 - 6.3e-158 523.5 12.6 7.8e-158 523.2 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85161.1 - 0.086 13.3 0.3 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85161.1 - 0.16 12.4 7.1 2 8.9 0.4 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85161.1 - 1.2 9.5 5.1 13 6.1 0.1 3.7 4 1 1 5 5 5 0 Tup N-terminal Pox_A32 PF04665.12 EAX85162.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85162.1 - 3e-05 24.3 0.2 0.00022 21.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX85162.1 - 0.00014 21.9 2.7 0.00031 20.8 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX85162.1 - 0.00016 21.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX85162.1 - 0.00032 20.5 0.1 0.00061 19.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX85162.1 - 0.0011 18.6 0.6 0.012 15.3 0.6 2.2 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX85162.1 - 0.0055 16.5 1.0 0.011 15.6 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85162.1 - 0.016 15.5 0.0 0.032 14.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX85162.1 - 0.039 14.4 0.1 0.32 11.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX85162.1 - 0.069 13.4 1.6 8.9 6.6 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Cytochrom_B562 PF07361.11 EAX85163.1 - 0.022 15.4 2.1 3.8 8.2 0.2 2.6 2 0 0 2 2 2 0 Cytochrome b562 DUF148 PF02520.17 EAX85163.1 - 0.066 13.3 2.7 3.8 7.7 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF150 PF02576.17 EAX85163.1 - 0.17 12.3 0.3 2.2 8.7 0.0 2.7 3 0 0 3 3 3 0 RimP N-terminal domain DUF3839 PF12943.7 EAX85164.1 - 2.7e-151 501.8 10.9 3.3e-151 501.5 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX85164.1 - 0.14 13.1 0.5 0.62 11.1 0.2 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX85164.1 - 0.25 11.8 3.1 0.54 10.8 0.2 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX85165.1 - 0.0085 15.8 0.1 0.022 14.5 0.0 1.6 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX85166.1 - 4.9e-67 225.1 2.5 6.5e-67 224.7 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85166.1 - 0.056 13.8 0.3 0.1 13.0 0.1 1.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta FliJ PF02050.16 EAX85167.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein IQ PF00612.27 EAX85168.1 - 1.1e-10 40.3 11.9 0.0031 17.2 0.7 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif MVP_shoulder PF11978.8 EAX85168.1 - 0.084 12.9 1.9 0.26 11.3 1.9 1.9 1 1 0 1 1 1 0 Shoulder domain PRD PF00874.20 EAX85168.1 - 0.085 13.2 5.2 0.69 10.3 0.1 2.5 2 0 0 2 2 2 0 PRD domain IBD PF10416.9 EAX85169.1 - 7.9e-35 119.7 3.1 1.2e-34 119.1 3.1 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD ADK_lid PF05191.14 EAX85171.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF5013 PF16405.5 EAX85171.1 - 0.051 13.8 1.2 0.066 13.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) Pkinase PF00069.25 EAX85172.1 - 1.9e-34 119.2 0.1 2.2e-34 119.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85172.1 - 4.2e-17 62.3 0.0 5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX85172.1 - 6.1e-10 38.4 0.1 7.4e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX85172.1 - 2.2e-05 23.9 0.0 4.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX85172.1 - 0.00071 19.0 0.3 0.00089 18.7 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX85172.1 - 0.0034 17.3 0.2 0.005 16.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX85172.1 - 0.037 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EAX85172.1 - 0.056 12.5 1.7 0.077 12.0 1.7 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 EAX85172.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 EAX85172.1 - 0.11 12.1 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EAX85172.1 - 0.13 11.8 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GPS2_interact PF15784.5 EAX85176.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85176.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX85178.1 - 0.012 15.7 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX85178.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal T5orf172 PF10544.9 EAX85179.1 - 0.00018 22.0 0.3 0.00047 20.6 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85179.1 - 0.029 14.2 0.3 0.055 13.3 0.3 1.6 1 1 0 1 1 1 0 KilA-N domain Lectin_legB PF00139.19 EAX85179.1 - 0.16 11.5 0.9 2.5 7.5 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX85180.1 - 4.6e-155 514.1 12.5 5.9e-155 513.8 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85180.1 - 0.071 13.6 1.5 0.34 11.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX85180.1 - 1.6 9.2 5.4 26 5.4 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85180.1 - 3.5 8.0 7.6 8.1 6.8 0.1 3.8 3 2 2 5 5 5 0 Tup N-terminal Raptor_N PF14538.6 EAX85181.1 - 5.1e-36 123.8 2.1 7.4e-36 123.3 0.6 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain COPI_assoc PF08507.10 EAX85182.1 - 0.038 14.0 20.3 0.056 13.5 20.3 1.2 1 0 0 1 1 1 0 COPI associated protein DUF2417 PF10329.9 EAX85182.1 - 1.5 8.2 10.8 1.8 7.9 10.8 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DoxX_3 PF13781.6 EAX85182.1 - 3.3 8.4 7.8 0.52 11.0 0.2 2.6 2 1 1 3 3 3 0 DoxX-like family TMP PF05017.14 EAX85185.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX85187.1 - 3.4e-06 27.0 0.5 3.4e-06 27.0 0.5 4.1 3 3 2 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX85187.1 - 0.007 16.0 17.9 0.24 11.0 1.4 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX85187.1 - 0.048 13.4 0.2 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2120 PF09893.9 EAX85187.1 - 0.69 10.0 3.8 2.8 8.0 0.5 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Antimicrobial_7 PF08102.11 EAX85188.1 - 0.076 13.3 2.0 0.23 11.7 2.0 2.0 1 1 0 1 1 1 0 Scorpion antimicrobial peptide Ank_2 PF12796.7 EAX85189.1 - 1.3e-21 76.9 0.3 2.4e-11 44.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85189.1 - 5.5e-21 74.6 0.3 8.5e-08 32.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX85189.1 - 1.4e-20 73.0 0.1 2.2e-07 31.0 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX85189.1 - 2.6e-17 62.4 0.1 1.1e-06 28.8 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX85189.1 - 3.4e-17 60.8 0.5 1.8e-05 24.8 0.1 4.8 5 0 0 5 5 4 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX85189.1 - 9.5e-09 35.0 15.7 2e-08 34.0 15.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX85189.1 - 0.00026 20.8 13.4 0.00054 19.8 13.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3447 PF11929.8 EAX85189.1 - 0.019 14.9 0.1 0.058 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) zf-RING_2 PF13639.6 EAX85189.1 - 0.02 15.2 16.5 0.044 14.1 16.5 1.6 1 0 0 1 1 1 0 Ring finger domain DUF1981 PF09324.10 EAX85189.1 - 0.048 13.5 0.0 0.84 9.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) zf-RING_5 PF14634.6 EAX85189.1 - 0.17 11.8 18.7 1.8 8.6 19.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAX85189.1 - 7.1 6.6 18.1 17 5.4 18.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 EAX85190.1 - 6.7e-08 32.7 0.2 0.032 14.5 0.0 4.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX85190.1 - 2e-07 31.6 5.2 0.12 13.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat KilA-N PF04383.13 EAX85191.1 - 6.8e-26 90.3 0.3 1.8e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX85191.1 - 0.053 14.2 1.3 13 6.6 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Parathyroid PF01279.17 EAX85191.1 - 0.081 13.6 0.0 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX85192.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85192.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85192.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85192.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) LRR_5 PF13306.6 EAX85193.1 - 6.1e-51 171.7 24.2 1.7e-22 79.8 0.9 4.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85193.1 - 1.9e-08 33.9 0.0 1.2 8.9 0.0 6.1 3 2 4 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAX85193.1 - 0.002 18.5 3.9 1.7 9.1 0.0 4.4 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) DUF560 PF04575.13 EAX85193.1 - 0.048 13.1 0.3 0.081 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF560) DUF1126 PF06565.12 EAX85194.1 - 1.3e-93 307.8 1.3 1.4e-33 114.8 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 EAX85194.1 - 0.0045 17.3 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator, RHH-like, CopG Peptidase_C1 PF00112.23 EAX85195.1 - 9.1e-28 97.8 1.9 9.9e-28 97.7 1.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Profilin PF00235.19 EAX85196.1 - 2.9e-21 76.1 0.5 3.2e-21 75.9 0.5 1.0 1 0 0 1 1 1 1 Profilin YgbA_NO PF11756.8 EAX85198.1 - 1.1 9.7 7.9 2.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter DUF3781 PF12636.7 EAX85200.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX85201.1 - 0.12 11.4 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85202.1 - 0.13 12.3 10.2 0.17 11.8 10.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX85202.1 - 0.34 8.5 14.5 0.43 8.2 14.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX85202.1 - 9.2 6.7 8.2 14 6.2 8.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX85204.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85204.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX85205.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF1289 PF06945.13 EAX85206.1 - 0.041 13.7 1.0 0.077 12.8 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) TMP PF05017.14 EAX85207.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85208.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP tRNA_synt_1c_R1 PF04558.15 EAX85209.1 - 0.0032 17.5 1.6 0.0072 16.3 0.1 2.0 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX85209.1 - 0.0056 16.3 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX85209.1 - 0.029 13.6 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4108 PF13390.6 EAX85211.1 - 2.8e-57 192.7 4.8 3.1e-57 192.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pentapeptide_4 PF13599.6 EAX85212.1 - 0.00026 21.1 20.1 0.027 14.6 3.5 5.2 2 2 3 5 5 5 4 Pentapeptide repeats (9 copies) TGBp3 PF02495.17 EAX85212.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Triple gene block 3 DUF3839 PF12943.7 EAX85213.1 - 6.9e-158 523.4 13.8 8.5e-158 523.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85213.1 - 2.9 8.4 8.1 1.5 9.3 0.5 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85214.1 - 3.2e-33 113.9 0.6 6.9e-33 112.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAX85215.1 - 4.6e-25 87.6 0.7 9.9e-25 86.6 0.0 1.9 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX85215.1 - 0.006 16.7 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX85216.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85216.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85216.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85216.1 - 0.00012 22.1 2.9 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85216.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85216.1 - 0.00099 19.0 0.4 0.0018 18.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85216.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85216.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX85216.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX85216.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85216.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85216.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85216.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DDE_Tnp_4 PF13359.6 EAX85217.1 - 7.5e-17 61.4 0.0 8.5e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX85217.1 - 2.6e-06 27.3 0.0 3.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Pox_A32 PF04665.12 EAX85220.1 - 1.9e-07 30.8 3.1 2.6e-07 30.3 3.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85220.1 - 0.0021 17.8 0.1 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX85220.1 - 0.062 12.8 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX85220.1 - 0.065 13.0 0.2 0.28 10.9 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX85220.1 - 0.093 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX85220.1 - 0.41 10.6 2.2 2.9 7.9 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF4107 PF13389.6 EAX85221.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX85221.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase P22_AR_C PF10548.9 EAX85222.1 - 0.091 12.9 0.1 20 5.5 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain PTR PF12789.7 EAX85223.1 - 5e-31 106.6 19.5 5.6e-30 103.2 15.1 3.7 2 2 2 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX85223.1 - 0.03 14.1 0.9 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) ResIII PF04851.15 EAX85224.1 - 4.6e-05 23.5 2.0 7.2e-05 22.8 2.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85224.1 - 0.00022 21.1 0.1 0.00035 20.4 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX85224.1 - 0.00048 20.4 0.0 0.00076 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX85224.1 - 0.0013 18.6 0.1 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85224.1 - 0.013 15.3 0.1 0.017 14.8 0.1 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EAX85224.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX85224.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX85224.1 - 0.06 13.0 1.8 0.071 12.8 0.3 1.7 1 1 0 2 2 2 0 SWI2/SNF2 ATPase TPK_catalytic PF04263.16 EAX85224.1 - 0.13 12.3 1.7 1.2 9.3 1.7 2.1 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX85224.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain APG12 PF04110.13 EAX85224.1 - 0.46 10.9 3.0 0.39 11.2 0.4 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Vac_Fusion PF02346.16 EAX85224.1 - 1 9.1 3.7 23 4.7 0.2 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 MULE PF10551.9 EAX85225.1 - 3.7e-11 43.3 0.6 1e-10 41.8 0.6 1.8 1 0 0 1 1 1 1 MULE transposase domain L27_1 PF09058.10 EAX85225.1 - 0.031 14.2 3.1 0.29 11.1 0.0 3.2 3 0 0 3 3 3 0 L27_1 X8 PF07983.13 EAX85225.1 - 0.08 13.6 0.4 3 8.6 0.2 2.5 2 0 0 2 2 2 0 X8 domain PapD_N PF00345.20 EAX85226.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX85226.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) LIM PF00412.22 EAX85227.1 - 8.4e-23 80.4 44.2 2.8e-11 43.5 7.0 3.3 3 0 0 3 3 3 3 LIM domain Utp21 PF04192.12 EAX85227.1 - 0.04 13.4 0.2 0.057 12.9 0.2 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain RPA_C PF08784.11 EAX85227.1 - 0.14 12.8 0.1 0.29 11.8 0.1 1.4 1 0 0 1 1 1 0 Replication protein A C terminal GPW_gp25 PF04965.14 EAX85228.1 - 0.16 11.8 0.0 0.16 11.8 0.0 4.1 5 0 0 5 5 5 0 Gene 25-like lysozyme Ank_2 PF12796.7 EAX85230.1 - 1.4e-64 214.7 29.4 4e-14 53.0 0.1 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85230.1 - 8.7e-51 169.7 11.9 4.9e-07 30.2 0.0 9.3 5 3 4 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX85230.1 - 5.5e-45 150.8 11.5 1e-09 38.5 0.0 8.5 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85230.1 - 7e-36 118.2 15.3 0.0003 21.0 0.0 12.6 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 EAX85230.1 - 1.9e-32 110.3 15.5 5.1e-06 26.7 0.0 12.3 13 0 0 13 13 13 6 Ankyrin repeat MULE PF10551.9 EAX85231.1 - 3e-13 50.0 0.1 6.3e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX85231.1 - 0.15 11.7 4.6 0.23 11.1 1.1 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX85231.1 - 0.49 10.6 5.6 1.4 9.2 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX85231.1 - 1.2 8.9 5.3 1.9 8.2 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DPM3 PF08285.11 EAX85232.1 - 0.18 12.0 0.6 2.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PRKCSH-like PF12999.7 EAX85233.1 - 0.00027 20.8 1.6 0.00097 19.0 1.6 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like SUIM_assoc PF16619.5 EAX85233.1 - 7.1 6.8 6.1 54 4.0 6.1 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pox_A32 PF04665.12 EAX85234.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85234.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85234.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85234.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX85235.1 - 1.5e-40 137.5 0.3 3.4e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Mito_fiss_reg PF05308.11 EAX85237.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX85237.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal T5orf172 PF10544.9 EAX85238.1 - 2.2e-06 28.1 0.2 5.8e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85238.1 - 0.0097 15.7 0.2 0.04 13.8 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX85238.1 - 0.034 13.7 1.1 0.34 10.4 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX85240.1 - 1.4e-42 144.0 0.8 2.6e-42 143.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85240.1 - 0.0094 16.6 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family Trypan_PARP PF05887.11 EAX85241.1 - 0.032 14.2 8.7 0.05 13.6 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85241.1 - 6.6 7.2 6.1 9.5 6.7 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX85242.1 - 0.039 14.4 1.5 0.053 14.0 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85242.1 - 0.044 12.8 0.1 0.045 12.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX85245.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX85246.1 - 0.0038 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX85247.1 - 1.5e-154 512.4 14.8 1.9e-154 512.1 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85247.1 - 1.1 9.7 7.3 2 8.9 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX85247.1 - 1.9 8.9 4.5 1.5 9.1 1.2 2.5 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Insulin_TMD PF17870.1 EAX85248.1 - 0.00045 20.2 0.7 0.00098 19.2 0.7 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment SKG6 PF08693.10 EAX85248.1 - 0.00085 18.7 3.8 0.0015 17.9 3.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 EAX85248.1 - 0.0028 17.6 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 EAX85248.1 - 0.0042 17.0 0.1 0.0074 16.2 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF5385 PF17359.2 EAX85248.1 - 0.0046 16.6 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Adeno_E3_CR2 PF02439.15 EAX85248.1 - 0.011 15.5 3.7 0.027 14.2 3.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EAX85248.1 - 0.029 15.2 0.1 0.067 14.1 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 EAX85248.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 EAX85248.1 - 0.063 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 EAX85248.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.25 EAX85249.1 - 7e-06 25.6 0.0 3e-05 23.5 0.0 2.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAX85249.1 - 0.0043 16.4 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3839 PF12943.7 EAX85250.1 - 3.2e-157 521.2 13.6 4.1e-157 520.9 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX85250.1 - 0.097 13.2 4.5 0.46 11.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85250.1 - 0.5 10.9 6.5 4.1 7.9 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85250.1 - 2.8 8.3 6.4 14 6.1 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal DUF2911 PF11138.8 EAX85252.1 - 0.028 14.3 0.0 55 3.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2911) AcetDehyd-dimer PF09290.11 EAX85252.1 - 0.048 13.9 0.1 84 3.3 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation ddrB-ParB PF18763.1 EAX85252.1 - 0.54 10.4 3.5 41 4.3 0.8 3.2 1 1 1 2 2 2 0 ddrB-like ParB superfamily domain LRR_8 PF13855.6 EAX85253.1 - 1.6e-31 107.8 38.6 2e-14 53.1 5.6 4.1 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EAX85253.1 - 2.6e-17 62.6 18.7 9.5e-08 32.2 2.4 4.6 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX85253.1 - 4.2e-07 29.6 3.5 3.7e-05 23.3 2.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 EAX85253.1 - 3e-06 27.2 3.7 3e-06 27.2 3.7 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EAX85253.1 - 6.2e-06 26.1 5.6 2.3 9.1 0.1 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 EAX85253.1 - 8.2e-06 25.5 7.9 2.1 8.6 0.4 5.2 5 0 0 5 5 5 3 Leucine Rich repeat FTH PF01827.27 EAX85253.1 - 0.04 13.7 5.3 2.2 8.1 0.0 2.6 2 1 0 2 2 2 0 FTH domain Cas3_C PF18395.1 EAX85253.1 - 0.13 12.8 0.0 0.66 10.5 0.0 2.0 2 1 0 2 2 2 0 Cas3 C-terminal domain LRR_2 PF07723.13 EAX85253.1 - 0.28 11.9 2.2 47 4.9 0.0 4.3 3 1 1 4 4 4 0 Leucine Rich Repeat FliJ PF02050.16 EAX85254.1 - 0.047 13.9 0.1 0.059 13.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein RepL PF05732.11 EAX85255.1 - 0.21 11.0 2.2 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) DUF3839 PF12943.7 EAX85258.1 - 7.7e-143 474.1 9.9 1.1e-142 473.6 9.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85258.1 - 0.71 10.4 5.7 4.1 7.9 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX85259.1 - 7.1e-07 29.7 0.2 2e-06 28.3 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85260.1 - 6.4e-29 100.1 0.1 9.9e-29 99.5 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF1493 PF07377.12 EAX85262.1 - 0.029 14.8 0.6 0.076 13.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) VIGSSK PF14773.6 EAX85263.1 - 0.28 11.3 1.8 17 5.6 0.2 2.2 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal DNA_pol_B_2 PF03175.13 EAX85264.1 - 1.3e-15 57.2 1.0 2.5e-15 56.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX85264.1 - 0.048 13.0 0.3 0.077 12.3 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein YmaF PF12788.7 EAX85265.1 - 0.12 12.9 1.4 1.3 9.7 1.4 2.1 1 1 0 1 1 1 0 YmaF family T5orf172 PF10544.9 EAX85266.1 - 1.8e-06 28.4 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85266.1 - 0.0043 16.9 1.2 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX85266.1 - 0.096 12.2 0.6 0.32 10.5 0.3 1.8 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX85267.1 - 1.7e-39 134.1 1.1 2.8e-39 133.4 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85267.1 - 0.015 15.9 0.1 0.038 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family ABC1 PF03109.16 EAX85267.1 - 1.5 9.0 4.7 1.7 8.8 0.1 2.7 2 1 1 3 3 3 0 ABC1 family PTR PF12789.7 EAX85268.1 - 2.8e-40 136.2 27.8 1.7e-34 117.7 15.9 6.0 4 3 2 6 6 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX85268.1 - 0.011 15.3 1.0 0.011 15.3 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX85268.1 - 0.086 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX85270.1 - 1.1e-155 516.2 14.6 1.4e-155 515.8 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85270.1 - 0.092 13.2 2.3 0.13 12.7 0.4 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX85270.1 - 0.14 11.6 0.7 0.66 9.4 0.0 2.0 2 1 1 3 3 3 0 SLOG cluster2 KELK PF15796.5 EAX85270.1 - 0.21 12.1 7.8 0.57 10.7 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85272.1 - 2.5e-117 390.6 13.3 3.3e-117 390.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX85272.1 - 0.017 15.4 0.7 0.13 12.5 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF29 KELK PF15796.5 EAX85272.1 - 0.027 14.9 3.7 1.3 9.6 0.1 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX85272.1 - 0.038 14.4 0.1 0.064 13.7 0.1 1.4 1 0 0 1 1 1 0 Fez1 PRD PF00874.20 EAX85272.1 - 0.093 13.0 6.1 0.4 11.0 0.1 3.1 4 0 0 4 4 4 0 PRD domain NTP_transf_6 PF06042.11 EAX85272.1 - 0.17 11.7 2.1 0.44 10.4 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DDR PF08841.10 EAX85274.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85275.1 - 0.04 13.9 8.0 0.062 13.3 8.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85275.1 - 3.3 8.2 5.0 4.7 7.7 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MULE PF10551.9 EAX85277.1 - 2.6e-10 40.6 1.5 3.1e-10 40.3 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX85277.1 - 0.019 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DUF3839 PF12943.7 EAX85278.1 - 2.8e-154 511.6 12.7 3.4e-154 511.3 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85278.1 - 0.057 13.9 1.4 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX85278.1 - 0.17 12.4 4.2 0.36 11.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85278.1 - 0.21 12.1 5.5 1.7 9.1 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX85278.1 - 0.41 11.0 2.9 1.4 9.3 1.1 2.6 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2939 PF11159.8 EAX85279.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) TALPID3 PF15324.6 EAX85280.1 - 2.4 5.7 13.7 3 5.4 13.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX85280.1 - 5.9 7.3 7.0 8.7 6.8 7.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX85281.1 - 0.097 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85281.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX85283.1 - 0.051 13.6 9.5 0.071 13.1 9.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX85283.1 - 3.6 5.1 15.4 4.4 4.9 15.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GPS2_interact PF15784.5 EAX85284.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85284.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX85285.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TMP PF05017.14 EAX85286.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85287.1 - 0.078 12.9 0.9 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP Metallophos PF00149.28 EAX85289.1 - 3e-30 106.3 0.4 4.3e-30 105.7 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX85289.1 - 0.0023 18.3 0.1 0.005 17.3 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX85289.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF2897 PF11446.8 EAX85290.1 - 2 8.4 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX85291.1 - 1.4e-61 206.6 5.7 1.6e-61 206.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Glycos_transf_2 PF00535.26 EAX85292.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Spo12 PF05032.12 EAX85293.1 - 0.54 10.2 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family TMP PF05017.14 EAX85294.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85295.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ABC_membrane_2 PF06472.15 EAX85298.1 - 4.4e-49 167.3 6.3 7e-49 166.6 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EAX85298.1 - 1.4e-20 74.2 0.0 3.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAX85298.1 - 0.0017 18.0 9.3 0.0056 16.4 9.3 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EAX85298.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EAX85298.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EAX85298.1 - 0.025 14.9 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EAX85298.1 - 0.033 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX85298.1 - 0.057 12.8 0.2 7.2 6.0 0.1 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAX85298.1 - 0.084 13.1 0.6 1.2 9.3 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 EAX85298.1 - 0.093 13.2 0.1 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAX85298.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 EAX85298.1 - 0.2 11.9 0.6 16 5.7 0.1 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF3839 PF12943.7 EAX85299.1 - 3.6e-156 517.8 12.1 4.4e-156 517.5 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85299.1 - 0.065 13.7 4.3 2 9.0 0.2 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX85299.1 - 0.096 13.1 0.2 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TPR_MLP1_2 PF07926.12 EAX85301.1 - 0.016 15.2 0.4 0.021 14.9 0.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX85301.1 - 0.059 13.2 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX85301.1 - 0.098 12.6 2.7 0.098 12.6 2.7 2.4 3 0 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX85302.1 - 8e-07 29.5 0.1 2.6e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX85302.1 - 0.072 12.9 0.5 0.66 9.8 0.2 2.5 2 1 0 2 2 2 0 KilA-N domain Lipid_DES PF08557.10 EAX85303.1 - 1.7 8.2 4.4 0.42 10.2 1.0 1.7 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) GPS2_interact PF15784.5 EAX85304.1 - 0.06 13.8 1.7 0.082 13.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain HD-ZIP_N PF04618.12 EAX85305.1 - 0.006 17.1 0.7 0.0077 16.7 0.7 1.2 1 0 0 1 1 1 1 HD-ZIP protein N terminus MMR1 PF08505.10 EAX85305.1 - 0.16 12.2 8.9 0.18 12.1 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein LpoB PF13036.6 EAX85305.1 - 0.35 10.8 7.0 0.89 9.5 6.8 1.7 1 1 1 2 2 2 0 Peptidoglycan-synthase activator LpoB Vfa1 PF08432.10 EAX85305.1 - 0.43 10.9 16.3 0.43 10.9 16.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 T2SSC PF11356.8 EAX85305.1 - 0.54 10.1 3.7 0.67 9.9 3.7 1.2 1 0 0 1 1 1 0 Type II secretion system protein C Med12-LCEWAV PF12145.8 EAX85305.1 - 0.66 8.8 6.1 0.76 8.5 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DDRGK PF09756.9 EAX85305.1 - 1 8.9 22.8 1.4 8.5 22.8 1.2 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 EAX85305.1 - 1.1 8.0 9.1 1.2 7.8 9.1 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EAX85305.1 - 1.5 8.6 18.0 1.8 8.4 18.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EAX85305.1 - 1.6 8.4 9.9 2 8.0 9.9 1.2 1 0 0 1 1 1 0 FAM176 family MDM10 PF12519.8 EAX85305.1 - 2.2 7.1 6.5 2.3 7.0 6.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SLC12 PF03522.15 EAX85305.1 - 2.4 7.1 9.1 2.6 7.0 9.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 EAX85305.1 - 2.6 8.2 7.1 2.6 8.1 7.1 1.2 1 0 0 1 1 1 0 DDHD domain ALMT PF11744.8 EAX85305.1 - 2.7 6.7 7.2 3 6.6 7.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter EIIBC-GUT_N PF03612.14 EAX85305.1 - 3 7.6 9.2 3.5 7.3 9.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Folate_carrier PF01770.18 EAX85305.1 - 3.1 6.4 3.3 3.4 6.3 3.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.14 EAX85305.1 - 3.4 5.8 11.8 3.6 5.7 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.12 EAX85305.1 - 3.5 6.9 15.3 3.7 6.8 15.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.7 EAX85305.1 - 3.9 5.5 7.3 4.2 5.4 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GNAT_acetyltr_2 PF13718.6 EAX85305.1 - 4 6.8 6.8 4 6.8 6.8 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CENP-N PF05238.13 EAX85305.1 - 4.6 6.4 9.5 4.7 6.4 9.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4746 PF15928.5 EAX85305.1 - 4.9 6.5 15.4 6.1 6.2 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 EAX85305.1 - 5.6 6.1 4.6 6.2 5.9 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EAX85305.1 - 6 5.5 9.8 6.2 5.5 9.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP70 PF00012.20 EAX85305.1 - 7.6 4.6 13.0 8 4.5 13.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Connexin PF00029.19 EAX85305.1 - 7.9 6.2 10.0 9 6.0 10.0 1.2 1 0 0 1 1 1 0 Connexin SBDS_C PF09377.10 EAX85307.1 - 1.9e-27 95.5 0.4 3.7e-27 94.6 0.4 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EAX85307.1 - 3.5e-24 84.7 0.7 2.8e-23 81.8 0.6 2.2 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein LANC_like PF05147.13 EAX85308.1 - 0.014 14.0 0.3 0.069 11.7 0.1 2.1 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Pox_A32 PF04665.12 EAX85309.1 - 3.5e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85309.1 - 0.0044 16.7 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX85309.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX85309.1 - 0.062 13.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85309.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX85309.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX85310.1 - 1.1e-43 147.6 0.9 1.9e-43 146.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85310.1 - 0.019 15.6 0.4 0.052 14.2 0.0 1.9 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX85311.1 - 7.2e-06 26.5 0.2 1.6e-05 25.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX85312.1 - 1.6e-151 502.5 13.1 2.1e-151 502.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX85312.1 - 0.048 14.2 2.4 0.18 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85312.1 - 0.089 13.3 2.2 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX85313.1 - 5.3e-72 241.3 4.2 6.9e-72 240.9 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX85314.1 - 0.034 14.0 1.3 0.058 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX85317.1 - 2.5e-71 239.1 4.2 3.7e-71 238.5 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85317.1 - 0.09 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX85318.1 - 4.7e-151 501.0 14.3 6e-151 500.7 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX85318.1 - 0.014 15.1 4.2 0.74 9.5 0.6 3.0 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit NTP_transf_6 PF06042.11 EAX85318.1 - 0.056 13.3 0.4 0.16 11.8 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX85318.1 - 0.28 11.5 3.2 20 5.6 0.0 3.6 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX85318.1 - 0.55 10.7 4.3 1.9 9.0 0.1 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85319.1 - 9.4e-153 506.6 15.0 1.2e-152 506.3 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX85319.1 - 0.055 13.1 3.8 0.3 10.7 0.2 3.0 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit Trns_repr_metal PF02583.17 EAX85319.1 - 0.068 13.5 0.0 6 7.3 0.0 2.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor NTP_transf_6 PF06042.11 EAX85319.1 - 0.19 11.6 1.6 0.43 10.4 0.7 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX85319.1 - 0.35 11.3 3.7 6.3 7.3 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85319.1 - 0.98 10.0 4.4 0.31 11.6 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Rx_N PF18052.1 EAX85319.1 - 1.3 9.4 4.4 4.8 7.5 0.1 3.2 2 2 1 3 3 3 0 Rx N-terminal domain rve PF00665.26 EAX85320.1 - 4.9e-09 36.4 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Inhibitor_I69 PF13734.6 EAX85320.1 - 0.00028 21.3 0.7 0.0026 18.1 0.7 2.6 1 1 0 1 1 1 1 Spi protease inhibitor DUF4107 PF13389.6 EAX85322.1 - 2.2e-72 242.5 3.1 3.1e-72 242.0 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85324.1 - 7e-153 507.0 13.1 8.9e-153 506.6 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX85324.1 - 0.068 13.5 0.9 0.27 11.5 0.8 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 PRD PF00874.20 EAX85324.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.1 5 0 0 5 5 5 0 PRD domain KELK PF15796.5 EAX85324.1 - 1.4 9.4 7.7 1.7 9.1 0.6 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Thioredoxin PF00085.20 EAX85325.1 - 6.5e-14 51.8 0.0 7.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAX85325.1 - 0.0055 16.9 0.1 0.0062 16.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 EAX85325.1 - 0.027 13.4 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin DUF3839 PF12943.7 EAX85326.1 - 4e-151 501.2 11.9 5.1e-151 500.9 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85326.1 - 0.098 13.1 0.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX85326.1 - 0.1 13.2 0.1 0.1 13.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX85326.1 - 0.27 11.6 3.0 14 6.1 0.1 3.3 4 0 0 4 4 4 0 Tup N-terminal DUF3839 PF12943.7 EAX85330.1 - 6.9e-150 497.2 11.7 8.1e-150 497.0 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85330.1 - 0.091 13.2 0.3 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85330.1 - 0.46 11.0 5.0 6 7.4 0.2 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AIP3 PF03915.13 EAX85332.1 - 0.00054 19.2 4.9 0.00072 18.8 4.9 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 NYD-SP28 PF14772.6 EAX85332.1 - 0.046 13.8 4.0 0.11 12.6 4.0 1.6 1 0 0 1 1 1 0 Sperm tail TSC22 PF01166.18 EAX85332.1 - 0.061 13.6 1.7 1.8 8.9 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 EAX85332.1 - 0.22 11.8 10.7 0.14 12.4 7.8 2.0 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Vps51 PF08700.11 EAX85332.1 - 1.9 8.6 7.9 2.2 8.4 0.2 3.0 2 1 0 2 2 2 0 Vps51/Vps67 Tup_N PF08581.10 EAX85332.1 - 2.1 8.7 8.5 2.5 8.4 6.7 2.2 1 1 1 2 2 2 0 Tup N-terminal ZapB PF06005.12 EAX85332.1 - 2.3 8.7 10.4 24 5.4 10.3 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF3447 PF11929.8 EAX85334.1 - 6.2e-08 32.5 1.4 1.9e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) DUF3452 PF11934.8 EAX85334.1 - 0.058 12.9 0.4 0.16 11.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) LPD28 PF18843.1 EAX85335.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 Large polyvalent protein associated domain 28 DUF2890 PF11081.8 EAX85335.1 - 0.11 12.6 0.1 0.11 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4107 PF13389.6 EAX85338.1 - 2.2e-69 232.8 3.4 2.5e-69 232.5 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX85338.1 - 0.099 11.0 1.1 0.13 10.6 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF1476 PF07345.11 EAX85338.1 - 0.11 12.8 0.5 0.16 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta LRR_4 PF12799.7 EAX85340.1 - 6.3e-39 131.3 71.9 5.6e-08 33.0 2.0 14.0 9 3 5 14 14 14 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX85340.1 - 1.1e-31 108.3 58.9 1.6e-07 31.0 0.6 12.3 5 5 9 14 14 14 10 Leucine rich repeat LRR_6 PF13516.6 EAX85340.1 - 5.5e-06 26.0 42.3 0.74 10.0 0.3 12.9 15 0 0 15 15 15 3 Leucine Rich repeat LRR_1 PF00560.33 EAX85340.1 - 0.0055 17.1 56.4 2.2 9.1 0.4 15.9 17 3 1 18 18 18 3 Leucine Rich Repeat RHH_4 PF13467.6 EAX85340.1 - 0.0056 16.5 0.4 0.02 14.8 0.1 2.0 2 0 0 2 2 2 1 Ribbon-helix-helix domain Phage_X PF05155.15 EAX85340.1 - 0.11 12.9 0.1 8.4 6.9 0.0 3.0 2 0 0 2 2 2 0 Phage X family efb-c PF12199.8 EAX85340.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal ABC_trans_CmpB PF06541.11 EAX85341.1 - 0.064 13.5 0.8 0.16 12.2 0.8 1.7 1 0 0 1 1 1 0 Putative ABC-transporter type IV Lipase_GDSL_3 PF14606.6 EAX85341.1 - 0.085 13.0 2.3 9.1 6.4 0.1 2.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family ANAPC3 PF12895.7 EAX85341.1 - 0.1 12.8 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 T5orf172 PF10544.9 EAX85342.1 - 0.0012 19.4 0.2 0.0029 18.1 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX85342.1 - 0.067 12.7 0.3 3.1 7.3 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX85343.1 - 9.6e-154 509.8 13.5 1.2e-153 509.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85343.1 - 1.3 9.5 5.3 5.2 7.6 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX85344.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX85345.1 - 5.4e-58 195.0 8.0 6e-58 194.8 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85345.1 - 0.11 12.8 0.1 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF4793 PF16041.5 EAX85346.1 - 0.097 12.8 3.7 0.29 11.3 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4793) TMEM154 PF15102.6 EAX85347.1 - 0.012 15.5 1.7 0.012 15.5 1.7 1.6 1 1 0 1 1 1 0 TMEM154 protein family DUF4577 PF15145.6 EAX85347.1 - 0.034 14.2 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Orf78 PF06024.12 EAX85347.1 - 0.059 13.7 3.1 0.12 12.7 3.1 1.8 1 1 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 EAX85347.1 - 0.059 14.3 0.9 0.11 13.4 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 EAX85347.1 - 0.064 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) FeoB_associated PF12669.7 EAX85347.1 - 0.079 13.4 0.5 0.14 12.6 0.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Collectrin PF16959.5 EAX85347.1 - 0.15 11.8 1.6 0.22 11.3 1.6 1.4 1 1 0 1 1 1 0 Renal amino acid transporter DUF4106 PF13388.6 EAX85350.1 - 4e-15 56.0 3.0 4e-15 56.0 3.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) VP4_2 PF08935.10 EAX85350.1 - 0.091 13.4 0.8 0.2 12.3 0.8 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit ArsC PF03960.15 EAX85350.1 - 3.9 7.6 7.2 0.51 10.4 0.2 3.0 2 1 0 3 3 3 0 ArsC family DUF4108 PF13390.6 EAX85351.1 - 1.5e-63 213.0 5.8 1.6e-63 212.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX85352.1 - 1.4 8.8 4.4 3 7.8 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX85353.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85353.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85353.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85353.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85353.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85353.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85353.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85353.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85353.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85353.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85353.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85353.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX85354.1 - 1.5e-39 134.3 2.3 1.6e-39 134.2 0.4 2.0 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85354.1 - 0.029 15.0 0.4 0.089 13.4 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX85355.1 - 2.1e-25 89.6 4.0 3.2e-25 89.0 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX85355.1 - 0.087 13.1 0.9 0.29 11.5 0.1 2.1 1 1 1 2 2 2 0 PRD domain RecO_C PF02565.15 EAX85355.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal Fib_alpha PF08702.10 EAX85356.1 - 4.5e-05 23.7 54.2 0.00065 19.9 11.2 3.9 2 1 2 4 4 4 3 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EAX85356.1 - 0.0003 20.4 15.1 0.0003 20.4 15.1 3.5 1 1 3 4 4 4 2 Golgin subfamily A member 5 UPF0242 PF06785.11 EAX85356.1 - 0.00037 20.7 10.5 0.00037 20.7 10.5 3.7 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 EAX85356.1 - 0.00075 19.8 3.5 0.00075 19.8 3.5 4.1 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EAX85356.1 - 0.001 19.3 57.9 0.032 14.5 4.9 5.3 1 1 4 5 5 5 2 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 EAX85356.1 - 0.021 15.4 34.1 0.34 11.5 0.7 7.5 2 2 5 8 8 8 0 SlyX TSC22 PF01166.18 EAX85356.1 - 0.025 14.9 2.0 0.025 14.9 2.0 6.8 5 3 3 8 8 8 0 TSC-22/dip/bun family NPV_P10 PF05531.12 EAX85356.1 - 0.081 13.4 14.3 0.98 9.9 0.1 5.0 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EAX85356.1 - 0.11 11.4 61.2 0.064 12.1 25.7 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAX85356.1 - 0.12 12.4 57.6 1.6 8.8 13.8 4.9 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EAX85356.1 - 0.18 11.2 65.9 0.16 11.3 23.0 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 EAX85356.1 - 0.18 9.9 54.9 1.9 6.6 54.9 2.1 1 1 0 1 1 1 0 HOOK protein SKA1 PF07160.12 EAX85356.1 - 0.34 10.7 46.4 0.45 10.3 14.1 3.7 1 1 2 4 4 4 0 Spindle and kinetochore-associated protein 1 DUF745 PF05335.13 EAX85356.1 - 0.35 10.6 36.9 0.023 14.4 14.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 EAX85356.1 - 0.59 10.0 11.1 0.88 9.5 0.1 5.0 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 EAX85356.1 - 0.74 9.4 62.2 6.4 6.4 24.8 4.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 EAX85356.1 - 1.8 9.0 57.8 2.3 8.6 22.8 3.4 1 1 2 3 3 3 0 Fez1 HMMR_N PF15905.5 EAX85356.1 - 2.8 7.3 64.5 0.056 12.9 31.0 3.3 1 1 2 3 3 2 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 EAX85356.1 - 4.5 7.3 22.0 8.3 6.5 0.5 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EAX85356.1 - 8.9 6.7 14.9 8 6.8 0.1 4.8 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 EAX85356.1 - 8.9 6.0 53.4 1.9 8.3 14.8 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family MF_alpha_N PF05436.11 EAX85357.1 - 0.031 14.2 0.7 0.17 11.8 0.7 2.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF2070 PF09843.9 EAX85357.1 - 6.4 4.9 6.4 0.81 7.9 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Ank_2 PF12796.7 EAX85358.1 - 9.2e-18 64.6 3.6 4.3e-09 36.8 0.0 4.4 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85358.1 - 5.6e-11 42.7 0.5 0.00014 22.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX85358.1 - 3.7e-10 39.6 4.3 3.7e-10 39.6 4.3 4.5 3 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX85358.1 - 2.8e-08 33.9 3.3 7.7e-06 26.1 0.0 4.3 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85358.1 - 4.6e-06 26.6 4.2 2.3 9.1 0.0 7.0 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 EAX85358.1 - 0.0011 19.3 0.0 5.8 7.5 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat RasGEF_N PF00618.20 EAX85358.1 - 0.48 10.7 5.0 0.67 10.2 0.2 3.2 2 2 0 3 3 3 0 RasGEF N-terminal motif LRR_5 PF13306.6 EAX85359.1 - 9.6e-127 416.8 89.6 1.5e-28 99.3 5.4 7.5 3 2 5 8 8 8 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85359.1 - 4.6e-25 87.2 2.1 0.00089 19.0 0.1 11.2 10 2 2 12 12 12 7 Leucine rich repeat LRR_4 PF12799.7 EAX85359.1 - 5.5e-06 26.6 12.2 2 9.0 0.1 8.2 9 1 0 9 9 9 2 Leucine Rich repeats (2 copies) STAT2_C PF12188.8 EAX85359.1 - 0.59 10.1 1.7 5.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal T5orf172 PF10544.9 EAX85360.1 - 1.1e-06 29.1 0.3 2.9e-06 27.8 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85360.1 - 0.0087 15.9 1.9 0.025 14.4 0.4 2.4 2 2 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX85360.1 - 0.014 14.9 0.8 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Trypan_PARP PF05887.11 EAX85361.1 - 0.12 12.4 8.6 0.18 11.8 8.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 EAX85364.1 - 9.2e-70 235.0 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85364.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85364.1 - 9.7e-05 21.8 0.1 0.00068 19.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX85364.1 - 0.0025 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 EAX85364.1 - 0.0058 17.1 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 PH domain bPH_3 PF14470.6 EAX85364.1 - 0.013 15.9 0.2 0.047 14.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial PH domain APH PF01636.23 EAX85364.1 - 0.066 13.1 0.0 0.46 10.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family GhoS PF11080.8 EAX85364.1 - 0.1 12.6 0.1 0.37 10.8 0.1 1.9 1 1 1 2 2 2 0 Endoribonuclease GhoS Cyclin_N PF00134.23 EAX85365.1 - 2.5e-23 82.2 0.1 6.7e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAX85365.1 - 4.6e-09 36.4 0.6 1.7e-08 34.6 0.0 2.0 2 1 0 2 2 2 1 Cyclin, C-terminal domain U-box PF04564.15 EAX85366.1 - 2.1e-05 24.6 0.1 4.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 U-box domain Ribosomal_L5_C PF00673.21 EAX85367.1 - 3.5e-17 62.3 0.0 5.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAX85367.1 - 1e-09 38.5 0.3 1.7e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Chromo PF00385.24 EAX85368.1 - 0.053 13.4 3.5 0.17 11.8 3.5 1.9 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pox_Ag35 PF03286.14 EAX85369.1 - 0.82 9.4 6.0 1.3 8.8 6.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MULE PF10551.9 EAX85370.1 - 2.5e-08 34.2 0.0 3.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain COX15-CtaA PF02628.15 EAX85371.1 - 0.0073 15.4 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein LELP1 PF15042.6 EAX85371.1 - 1.3 9.5 3.8 0.66 10.4 1.9 1.5 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Vps51 PF08700.11 EAX85372.1 - 0.061 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Vps51/Vps67 zf-C2HCIx2C PF10782.9 EAX85372.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger DUF3839 PF12943.7 EAX85373.1 - 6.5e-158 523.5 13.0 7.5e-158 523.3 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85373.1 - 2.7 8.5 7.7 2.5 8.6 0.3 3.5 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TH1 PF04858.13 EAX85375.1 - 1.8e-20 73.1 0.1 6.3e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 TH1 protein CelTOS PF18659.1 EAX85375.1 - 7e-05 23.2 0.1 0.00024 21.5 0.0 1.9 2 0 0 2 2 2 1 Cell-traversal protein for ookinetes and sporozoites VasI PF11319.8 EAX85375.1 - 0.16 11.7 0.6 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 NEAT PF05031.12 EAX85376.1 - 0.05 14.2 0.6 0.09 13.4 0.2 1.6 2 0 0 2 2 2 0 Iron Transport-associated domain DUF2870 PF11069.8 EAX85376.1 - 0.084 13.3 3.1 0.16 12.4 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) PG_binding_2 PF08823.11 EAX85377.1 - 0.012 15.9 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Transpos_assoc PF13963.6 EAX85377.1 - 0.015 15.6 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Transposase-associated domain Myb_DNA-binding PF00249.31 EAX85378.1 - 6.2e-27 93.5 0.4 1.3e-12 47.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85378.1 - 4.8e-18 65.2 0.2 1.6e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85378.1 - 0.00093 19.2 0.1 1.1 9.3 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX85378.1 - 0.004 17.0 0.1 0.012 15.5 0.1 1.9 1 1 0 1 1 1 1 Myb DNA-binding like DUF4625 PF15418.6 EAX85380.1 - 0.0017 18.6 3.9 3.6 7.9 0.0 4.9 2 1 2 5 5 5 2 Domain of unknown function (DUF4625) ETRAMP PF09716.10 EAX85380.1 - 0.011 15.8 0.2 0.023 14.7 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Protocadherin PF08374.11 EAX85380.1 - 0.016 15.2 0.3 0.03 14.3 0.3 1.4 1 0 0 1 1 1 0 Protocadherin DUF4083 PF13314.6 EAX85380.1 - 0.052 13.5 0.6 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Sigma_reg_N PF13800.6 EAX85380.1 - 0.1 12.9 0.6 0.3 11.4 0.6 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal RIFIN PF02009.16 EAX85380.1 - 4.1 7.2 7.4 0.6 10.0 2.9 1.8 2 0 0 2 2 2 0 Rifin TMEM154 PF15102.6 EAX85381.1 - 8.1e-05 22.6 3.0 0.00018 21.4 1.8 2.2 2 0 0 2 2 2 1 TMEM154 protein family MG2 PF01835.19 EAX85381.1 - 0.00079 19.8 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 MG2 domain Orf78 PF06024.12 EAX85381.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) DUF4625 PF15418.6 EAX85381.1 - 0.0041 17.3 4.1 1.6 9.0 0.0 4.0 3 2 1 4 4 4 1 Domain of unknown function (DUF4625) Sigma_reg_N PF13800.6 EAX85381.1 - 0.0045 17.2 0.3 0.015 15.5 0.3 1.9 1 0 0 1 1 1 1 Sigma factor regulator N-terminal ODV-E18 PF10717.9 EAX85381.1 - 0.012 15.5 0.8 0.029 14.3 0.1 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Wzt_C PF14524.6 EAX85381.1 - 0.012 15.6 1.1 1.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Wzt C-terminal domain Cadherin PF00028.17 EAX85381.1 - 0.029 14.8 1.5 0.56 10.7 0.1 2.8 2 0 0 2 2 2 0 Cadherin domain ETRAMP PF09716.10 EAX85381.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ly49 PF08391.10 EAX85381.1 - 0.094 13.1 0.3 3.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TMEM51 PF15345.6 EAX85381.1 - 0.099 12.5 0.8 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 Insulin_TMD PF17870.1 EAX85381.1 - 0.25 11.4 3.0 0.65 10.1 3.0 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EMP24_GP25L PF01105.24 EAX85381.1 - 1.8 8.5 7.6 0.56 10.1 0.4 2.8 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Big_7 PF17957.1 EAX85381.1 - 3.2 8.6 14.5 0.3 11.9 1.8 4.4 4 1 0 4 4 4 0 Bacterial Ig domain TMP PF05017.14 EAX85385.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX85387.1 - 6e-157 520.3 13.6 7.5e-157 520.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX85387.1 - 0.041 14.1 1.5 0.081 13.2 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function DUF29 KELK PF15796.5 EAX85387.1 - 0.36 11.3 6.8 2.5 8.6 0.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85387.1 - 0.87 10.1 5.8 0.52 10.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX85388.1 - 3e-05 23.6 0.5 3.4e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85388.1 - 0.0021 17.7 0.1 0.0024 17.5 0.1 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85388.1 - 0.019 14.7 0.1 0.053 13.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85388.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) SET_assoc PF11767.8 EAX85388.1 - 0.23 11.1 1.1 11 5.8 0.2 2.4 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated DUF2666 PF10869.8 EAX85388.1 - 0.26 11.5 2.1 1.2 9.3 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX85389.1 - 1.2e-34 118.5 0.5 2.7e-34 117.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85389.1 - 0.024 14.8 0.0 0.086 13.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX85389.1 - 2.5 8.6 8.8 13 6.3 3.6 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 T5orf172 PF10544.9 EAX85390.1 - 9.3e-07 29.3 0.3 2.3e-06 28.1 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85390.1 - 0.01 15.7 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX85390.1 - 0.063 12.8 0.6 0.61 9.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX85391.1 - 1.1e-25 90.5 4.9 1.6e-25 90.0 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX85393.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX85393.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX85394.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP T5orf172 PF10544.9 EAX85395.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PKcGMP_CC PF16808.5 EAX85397.1 - 0.039 13.8 1.7 0.096 12.6 1.5 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4107 PF13389.6 EAX85398.1 - 9.4e-50 168.9 1.2 1.1e-49 168.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FAS_N PF17828.1 EAX85399.1 - 0.003 17.6 0.2 0.0049 16.9 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Peptidase_C14 PF00656.22 EAX85399.1 - 0.038 13.9 0.1 0.044 13.7 0.1 1.1 1 0 0 1 1 1 0 Caspase domain DinB PF05163.12 EAX85399.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 DinB family Beach PF02138.18 EAX85401.1 - 2.4e-85 286.3 1.7 3.7e-85 285.6 0.0 2.1 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX85401.1 - 0.003 17.6 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH PSP PF04046.16 EAX85403.1 - 0.069 13.0 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85404.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85405.1 - 0.022 15.2 0.4 0.045 14.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX85406.1 - 2.7e-34 117.0 26.7 3.5e-29 100.6 13.0 3.9 4 1 1 5 5 5 2 Phage tail repeat like MULE PF10551.9 EAX85408.1 - 1.3e-11 44.7 0.1 2.4e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX85408.1 - 0.046 14.1 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX85408.1 - 0.096 13.0 0.3 0.26 11.6 0.1 1.9 2 0 0 2 2 2 0 PWI domain DUF4107 PF13389.6 EAX85409.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85410.1 - 5.4e-150 497.5 11.5 7.3e-150 497.1 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GCN5L1 PF06320.13 EAX85410.1 - 0.029 14.5 0.6 0.66 10.1 0.0 3.0 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Fez1 PF06818.15 EAX85410.1 - 0.039 14.4 0.7 0.13 12.7 0.1 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX85410.1 - 0.098 12.5 0.6 0.34 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX85410.1 - 0.1 12.9 0.7 2.2 8.6 0.1 3.1 3 1 1 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX85410.1 - 1.8 9.1 5.1 2.3 8.7 0.6 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85411.1 - 8.6e-140 464.1 12.8 2.4e-139 462.7 12.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85411.1 - 1.4 9.5 6.3 2.3 8.7 1.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX85412.1 - 4e-23 81.2 14.4 6.7e-23 80.5 7.0 5.2 5 1 0 5 5 5 2 Phage tail repeat like DUF1493 PF07377.12 EAX85413.1 - 0.016 15.7 0.5 0.033 14.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX85414.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85415.1 - 0.33 10.8 3.4 0.25 11.2 0.4 2.3 2 1 0 2 2 2 0 PSP PSP PF04046.16 EAX85416.1 - 0.087 12.7 0.7 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX85417.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX85417.1 - 0.062 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85418.1 - 0.057 13.9 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX85419.1 - 7.6e-94 313.7 7.3 8.6e-94 313.5 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX85419.1 - 0.09 13.1 1.0 0.19 12.0 1.0 1.7 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3839 PF12943.7 EAX85420.1 - 5.8e-21 75.1 3.0 9.8e-21 74.3 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX85420.1 - 0.044 14.1 0.8 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain DUF1269 PF06897.12 EAX85422.1 - 0.68 10.2 5.4 1.1 9.6 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Pox_A32 PF04665.12 EAX85423.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85423.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85423.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85423.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX85424.1 - 6e-43 145.2 0.3 1.5e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85424.1 - 0.064 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Parathyroid hormone family T5orf172 PF10544.9 EAX85425.1 - 2.7e-06 27.8 0.1 1.1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX85425.1 - 0.06 12.9 0.3 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX85425.1 - 0.084 12.7 0.5 0.53 10.1 0.2 2.4 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX85426.1 - 3.2e-121 403.3 12.9 4e-121 403.0 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85426.1 - 0.18 12.3 4.5 1.2 9.6 0.0 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX85427.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85428.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP CTD PF12815.7 EAX85430.1 - 2.3e-18 66.5 34.1 0.00024 21.6 1.9 6.1 1 1 3 4 4 4 4 Spt5 C-terminal nonapeptide repeat binding Spt4 Glyoxalase_3 PF13468.6 EAX85430.1 - 1.7 8.7 20.7 1.9e+03 -1.2 0.0 6.6 1 1 1 2 2 2 0 Glyoxalase-like domain DUF4107 PF13389.6 EAX85431.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3256 PF11644.8 EAX85432.1 - 0.063 12.8 0.6 0.073 12.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Mito_fiss_reg PF05308.11 EAX85433.1 - 0.11 12.6 0.4 0.11 12.6 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator KilA-N PF04383.13 EAX85435.1 - 5.7e-34 116.3 0.8 1e-33 115.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85435.1 - 0.00088 19.4 0.0 0.0026 17.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX85435.1 - 0.025 15.0 4.5 0.53 10.8 0.6 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spo12 PF05032.12 EAX85436.1 - 0.44 10.5 6.6 0.2 11.6 2.9 2.2 3 1 0 3 3 3 0 Spo12 family T5orf172 PF10544.9 EAX85437.1 - 1.3e-07 32.1 0.3 2.6e-07 31.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX85437.1 - 0.14 12.8 0.4 0.41 11.4 0.4 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3839 PF12943.7 EAX85438.1 - 3.7e-158 524.3 12.5 4.6e-158 524.0 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85438.1 - 0.93 10.0 5.7 2.1 8.8 0.9 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase adh_short PF00106.25 EAX85439.1 - 9.7e-21 74.1 0.0 1.2e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAX85439.1 - 8e-10 38.9 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAX85439.1 - 2.9e-08 33.5 0.0 3.6e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EAX85439.1 - 7.4e-06 25.3 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EAX85439.1 - 0.00055 19.5 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAX85439.1 - 0.0033 17.7 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EAX85439.1 - 0.069 12.2 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 EAX85439.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spo12 PF05032.12 EAX85440.1 - 0.54 10.2 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Alpha-amylase PF00128.24 EAX85441.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain B12-binding PF02310.19 EAX85441.1 - 0.009 16.1 0.0 0.031 14.3 0.0 1.7 2 0 0 2 2 2 1 B12 binding domain Malic_M PF03949.15 EAX85441.1 - 0.34 10.1 0.7 0.89 8.8 0.3 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain GPS2_interact PF15784.5 EAX85443.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 EAX85445.1 - 2.7e-29 101.1 1.0 2e-13 50.3 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85445.1 - 5e-26 90.7 6.0 5.8e-17 61.7 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85445.1 - 0.00029 20.8 4.0 0.11 12.5 0.1 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX85445.1 - 0.0032 17.6 5.8 1.3 9.2 0.2 3.2 1 1 1 2 2 2 2 Rap1 Myb domain SOSSC PF15925.5 EAX85445.1 - 0.026 15.8 0.5 0.052 14.9 0.5 1.5 1 0 0 1 1 1 0 SOSS complex subunit C Myb_DNA-bind_4 PF13837.6 EAX85445.1 - 0.038 14.4 4.7 0.12 12.7 0.6 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EAX85445.1 - 0.072 13.2 0.3 1.6 8.9 0.1 2.2 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LRV PF01816.17 EAX85446.1 - 0.7 10.4 2.6 46 4.7 0.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat variant YmaF PF12788.7 EAX85447.1 - 0.14 12.7 1.9 6.6 7.3 0.1 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX85447.1 - 0.68 10.2 6.3 4 7.9 0.7 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat Gly-zipper_Omp PF13488.6 EAX85450.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX85450.1 - 0.25 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX85450.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX85451.1 - 8.9e-78 259.1 12.1 1e-77 258.9 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TMP PF05017.14 EAX85452.1 - 0.089 13.4 2.2 37 5.6 0.1 3.6 3 0 0 3 3 3 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX85453.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX85453.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX85453.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Thioredoxin_7 PF13899.6 EAX85454.1 - 0.0014 18.8 0.1 0.026 14.7 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like EMC3_TMCO1 PF01956.16 EAX85454.1 - 0.14 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MKT1_N PF12247.8 EAX85454.1 - 0.16 12.3 0.3 3.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF4108 PF13390.6 EAX85457.1 - 1.7e-62 209.6 6.3 1.9e-62 209.4 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAX85459.1 - 3e-05 24.1 0.1 4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85459.1 - 0.0007 19.4 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85459.1 - 0.0021 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX85459.1 - 0.0032 17.7 0.0 0.0046 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85459.1 - 0.0089 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX85459.1 - 0.036 13.5 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX85459.1 - 0.059 13.1 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX85459.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX85459.1 - 0.2 11.4 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain PTR PF12789.7 EAX85461.1 - 4.9e-34 116.2 32.4 9.4e-21 73.6 12.5 4.7 4 2 1 5 5 5 2 Phage tail repeat like RACo_linker PF17650.1 EAX85461.1 - 0.00099 18.9 1.5 3.1 7.7 0.0 3.2 2 1 1 3 3 3 2 RACo linker region PH_TFIIH PF08567.11 EAX85461.1 - 0.048 14.0 1.8 4.3 7.7 0.1 2.8 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain Macoilin PF09726.9 EAX85461.1 - 0.6 8.6 10.4 0.77 8.2 10.4 1.1 1 0 0 1 1 1 0 Macoilin family VirDNA-topo-I_N PF09266.10 EAX85461.1 - 0.6 10.3 2.6 2 8.6 0.2 2.7 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal TMPIT PF07851.13 EAX85461.1 - 5.3 6.2 7.8 0.53 9.5 3.4 1.6 2 0 0 2 2 2 0 TMPIT-like protein Lipoprotein_2 PF00921.17 EAX85461.1 - 5.8 6.4 11.2 0.58 9.7 5.8 1.9 1 1 0 2 2 2 0 Borrelia lipoprotein DUF1493 PF07377.12 EAX85462.1 - 0.1 13.1 0.7 0.24 11.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pro_3_hydrox_C PF05373.11 EAX85464.1 - 0.038 14.1 0.2 0.055 13.6 0.2 1.3 1 1 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Ank_5 PF13857.6 EAX85464.1 - 0.067 13.5 0.2 0.097 13.0 0.2 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 EAX85465.1 - 0.00015 21.9 1.7 0.0003 20.9 0.1 2.1 2 1 0 2 2 2 1 F5/8 type C domain DUF2968 PF11180.8 EAX85465.1 - 0.00056 19.6 1.7 0.002 17.8 1.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) HAP1_N PF04849.13 EAX85465.1 - 0.0025 17.1 3.9 0.0033 16.7 3.9 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF3450 PF11932.8 EAX85465.1 - 0.006 15.9 4.4 0.0094 15.3 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ZapB PF06005.12 EAX85465.1 - 0.015 15.7 6.1 0.027 14.9 6.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB APG17 PF04108.12 EAX85465.1 - 0.021 13.9 2.7 0.03 13.4 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 APG6_N PF17675.1 EAX85465.1 - 0.036 14.6 3.2 0.056 14.0 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 EAX85465.1 - 0.075 13.3 3.8 0.12 12.6 2.6 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper Lectin_N PF03954.14 EAX85465.1 - 0.078 12.7 3.5 0.15 11.8 3.5 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EAX85465.1 - 0.44 10.6 4.3 0.77 9.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.9 EAX85465.1 - 0.69 9.8 7.6 1.3 8.9 7.6 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain bZIP_1 PF00170.21 EAX85465.1 - 3 8.0 7.7 3.4 7.8 3.5 2.2 1 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EAX85465.1 - 6.2 6.7 8.0 9.4 6.1 6.2 1.9 1 1 1 2 2 2 0 Septum formation initiator mRNA_decap_C PF16741.5 EAX85466.1 - 0.12 11.7 0.6 0.36 10.2 0.2 2.0 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF3723 PF12520.8 EAX85466.1 - 0.16 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) DUF3839 PF12943.7 EAX85468.1 - 3.7e-141 468.6 9.5 4.7e-141 468.3 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85468.1 - 1.1 9.8 7.9 2.6 8.6 1.2 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf-C4pol PF14260.6 EAX85468.1 - 1.6 9.2 4.6 7.3 7.1 0.2 2.7 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta T5orf172 PF10544.9 EAX85469.1 - 3.3e-06 27.6 0.0 8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85469.1 - 0.013 15.3 2.1 0.078 12.8 1.0 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAX85469.1 - 0.096 13.6 0.2 1.8 9.6 0.0 2.2 2 0 0 2 2 2 0 FRG domain 3HCDH_N PF02737.18 EAX85470.1 - 0.039 13.8 0.1 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIA PF03153.13 EAX85470.1 - 0.049 13.6 26.8 0.06 13.3 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSP PF04046.16 EAX85471.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3213 PF11491.8 EAX85473.1 - 0.042 14.0 0.5 0.1 12.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Ras PF00071.22 EAX85475.1 - 4.6e-55 185.6 0.2 5.4e-55 185.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX85475.1 - 1.1e-32 112.7 0.1 1.7e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX85475.1 - 5.1e-16 58.6 0.1 6.6e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX85475.1 - 7.7e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX85475.1 - 3.2e-05 23.4 0.2 4.3e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX85475.1 - 5.9e-05 23.0 0.0 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EAX85475.1 - 0.0004 19.9 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX85475.1 - 0.0004 19.9 0.1 0.0039 16.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 EAX85475.1 - 0.0011 18.3 1.8 0.39 9.8 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Septin PF00735.18 EAX85475.1 - 0.006 15.9 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Septin DUF5034 PF16437.5 EAX85475.1 - 0.025 14.5 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5034) PduV-EutP PF10662.9 EAX85475.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EAX85475.1 - 0.035 13.9 0.3 0.099 12.4 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein LppX_LprAFG PF07161.13 EAX85475.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein Sel1 PF08238.12 EAX85476.1 - 2.1e-55 183.9 40.0 5.4e-09 36.4 1.4 10.6 12 0 0 12 12 12 9 Sel1 repeat RelB_N PF18506.1 EAX85476.1 - 0.088 12.6 0.2 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain TPR_7 PF13176.6 EAX85476.1 - 5.3 7.3 17.1 15 5.9 0.1 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAX85476.1 - 8.8 6.4 12.6 28 4.7 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.7 EAX85477.1 - 9.8e-36 122.2 0.3 2.9e-19 69.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX85477.1 - 1.5e-26 91.6 0.1 5.6e-05 23.4 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAX85477.1 - 2.6e-21 75.7 0.0 1.6e-07 31.7 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85477.1 - 1.1e-20 71.4 0.7 0.0075 16.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX85477.1 - 3.5e-20 71.8 2.9 1.5e-08 34.7 0.1 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) BACK PF07707.15 EAX85477.1 - 0.0063 16.6 0.6 0.019 15.1 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch SpoU_sub_bind PF08032.12 EAX85477.1 - 0.058 13.7 0.1 0.57 10.5 0.0 2.8 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding TetR_C_8 PF14278.6 EAX85477.1 - 5.7 7.1 9.2 1.3 9.2 2.2 3.1 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region DUF3447 PF11929.8 EAX85479.1 - 1.1e-28 99.0 0.5 1.1e-28 99.0 0.5 3.1 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX85479.1 - 0.00016 22.2 0.0 0.00081 19.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF4533 PF15047.6 EAX85479.1 - 0.053 13.1 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DHHC PF01529.20 EAX85480.1 - 9.4e-23 80.8 18.9 9.4e-23 80.8 18.9 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase TPR_2 PF07719.17 EAX85481.1 - 1.1e-18 65.8 6.1 0.0006 19.7 0.6 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EAX85481.1 - 1.6e-12 46.6 11.6 9.8e-06 25.2 0.9 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX85481.1 - 2.6e-11 43.1 10.4 0.024 15.0 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAX85481.1 - 2.8e-08 33.9 0.6 0.028 15.1 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX85481.1 - 4e-08 32.8 9.5 0.79 10.1 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX85481.1 - 3.8e-07 30.5 1.1 0.11 13.1 0.1 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX85481.1 - 4.9e-06 26.9 0.3 0.97 10.4 0.0 4.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX85481.1 - 5.7e-06 26.5 3.4 0.035 14.4 0.3 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX85481.1 - 7.6e-05 23.3 0.1 2 9.2 0.1 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX85481.1 - 0.00022 21.4 5.4 0.046 14.0 0.2 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EAX85481.1 - 0.00088 18.9 0.1 0.00088 18.9 0.1 4.6 6 0 0 6 6 6 1 TPR repeat TPR_15 PF13429.6 EAX85481.1 - 0.0012 18.1 0.5 1.3 8.1 0.0 3.5 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX85481.1 - 0.0017 18.3 0.1 0.43 10.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EAX85481.1 - 0.0095 15.7 0.0 2.5 7.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain ApoLp-III PF07464.11 EAX85481.1 - 0.16 12.0 1.6 9.3 6.3 0.1 3.3 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TPR_3 PF07720.12 EAX85481.1 - 0.26 11.3 11.0 0.2 11.7 2.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TRIF-NTD PF17798.1 EAX85482.1 - 0.07 13.2 0.5 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 TRIF N-terminal domain PAXIP1_C PF15364.6 EAX85482.1 - 1 9.7 8.5 2.1 8.7 8.5 1.5 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Vps51 PF08700.11 EAX85483.1 - 2.3e-21 75.7 2.8 8.4e-21 73.9 2.8 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 EAX85483.1 - 1.3e-12 47.9 7.4 1.3e-12 47.9 7.4 2.4 3 0 0 3 3 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 EAX85483.1 - 8.4e-12 44.4 3.9 2.5e-11 42.9 3.9 1.8 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 EAX85483.1 - 2.5e-05 23.7 8.5 2.5e-05 23.7 8.5 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Ax_dynein_light PF10211.9 EAX85483.1 - 0.00051 20.0 2.5 0.0011 19.0 2.5 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain COG5 PF10392.9 EAX85483.1 - 0.0062 16.7 3.0 0.014 15.6 1.4 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 YabA PF06156.13 EAX85483.1 - 0.0093 16.6 0.7 0.068 13.8 0.6 2.6 2 0 0 2 2 1 1 Initiation control protein YabA FliJ PF02050.16 EAX85483.1 - 0.018 15.2 3.6 0.057 13.7 3.6 1.8 1 0 0 1 1 1 0 Flagellar FliJ protein KxDL PF10241.9 EAX85483.1 - 0.028 14.7 1.8 0.096 13.0 1.8 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein Occludin_ELL PF07303.13 EAX85483.1 - 0.034 14.9 3.8 0.12 13.1 2.7 2.5 1 1 0 1 1 1 0 Occludin homology domain Phage_GP20 PF06810.11 EAX85483.1 - 0.041 13.7 2.1 0.11 12.3 2.1 1.9 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mt_ATP-synt_D PF05873.12 EAX85483.1 - 0.051 13.4 2.2 0.17 11.8 2.2 1.9 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) SlyX PF04102.12 EAX85483.1 - 0.088 13.4 1.5 0.17 12.6 0.1 2.2 2 0 0 2 2 1 0 SlyX Laminin_II PF06009.12 EAX85483.1 - 0.14 12.2 4.5 0.085 12.9 1.1 2.4 2 1 0 2 2 2 0 Laminin Domain II Filament PF00038.21 EAX85483.1 - 0.15 11.6 6.1 0.27 10.8 2.6 2.6 3 0 0 3 3 3 0 Intermediate filament protein COG2 PF06148.11 EAX85483.1 - 0.17 12.0 7.7 0.03 14.4 2.1 2.7 4 0 0 4 4 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 EAX85483.1 - 0.42 10.5 6.4 0.12 12.2 2.8 2.1 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain Seryl_tRNA_N PF02403.22 EAX85483.1 - 0.43 10.8 3.6 1.1 9.6 1.0 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 EAX85483.1 - 0.58 10.2 4.0 1.1 9.3 3.3 1.8 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 EAX85483.1 - 0.77 10.2 3.7 3.1 8.3 2.5 2.8 2 1 0 2 2 1 0 Snapin/Pallidin YtxH PF12732.7 EAX85483.1 - 0.95 10.0 5.1 23 5.6 0.0 3.9 4 1 0 4 4 3 0 YtxH-like protein DUF1664 PF07889.12 EAX85483.1 - 1.3 9.1 5.0 2.5 8.1 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EAX85483.1 - 2.2 8.5 5.8 4.6 7.5 3.8 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EAX85483.1 - 2.6 8.5 6.4 0.56 10.7 0.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB KilA-N PF04383.13 EAX85485.1 - 3.3e-22 78.5 0.0 6.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX85486.1 - 2e-158 525.2 13.3 2.4e-158 524.9 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85486.1 - 0.12 12.8 0.2 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85486.1 - 1.3 9.5 7.1 2.1 8.8 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX85487.1 - 1.7e-06 28.5 0.3 7.3e-06 26.5 0.2 2.1 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX85488.1 - 1.8e-38 130.8 1.0 2.8e-38 130.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85488.1 - 0.0033 18.0 0.4 0.02 15.5 0.0 2.3 3 0 0 3 3 3 1 Parathyroid hormone family Mito_fiss_reg PF05308.11 EAX85489.1 - 0.11 12.5 0.4 0.12 12.5 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX85489.1 - 0.85 9.0 2.5 0.83 9.1 2.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4107 PF13389.6 EAX85490.1 - 2.1e-72 242.6 4.5 2.5e-72 242.3 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX85492.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX85494.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX85495.1 - 0.0035 17.0 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX85496.1 - 2.5e-146 485.5 10.5 3.1e-146 485.2 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Lectin_legB PF00139.19 EAX85497.1 - 0.0012 18.4 0.5 0.3 10.6 0.2 2.1 2 0 0 2 2 2 2 Legume lectin domain T5orf172 PF10544.9 EAX85497.1 - 0.0044 17.5 0.0 0.0083 16.7 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85497.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain FYVE_2 PF02318.16 EAX85498.1 - 0.043 14.0 0.3 0.083 13.1 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3839 PF12943.7 EAX85500.1 - 8.3e-154 510.0 15.8 1e-153 509.7 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85500.1 - 0.063 13.7 2.6 0.13 12.7 0.6 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX85500.1 - 0.086 12.7 1.2 0.23 11.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX85500.1 - 0.16 12.6 5.1 0.23 12.0 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX85500.1 - 0.26 11.6 2.0 0.94 9.8 0.5 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX85500.1 - 0.42 11.1 7.3 2.3 8.7 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UBA PF00627.31 EAX85501.1 - 2.2e-05 24.3 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF1840 PF08895.11 EAX85501.1 - 0.53 10.6 4.3 0.34 11.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) LT-IIB PF06453.11 EAX85502.1 - 0.04 13.8 0.1 0.14 12.0 0.0 1.8 1 1 1 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF3839 PF12943.7 EAX85503.1 - 2.8e-157 521.4 13.9 3.5e-157 521.1 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) RasGAP_C PF03836.15 EAX85503.1 - 0.087 13.0 0.2 0.087 13.0 0.2 1.8 2 0 0 2 2 2 0 RasGAP C-terminus KELK PF15796.5 EAX85503.1 - 2.9 8.4 8.4 1.9 9.0 1.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX85504.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85505.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85506.1 - 0.052 14.0 0.2 0.089 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX85509.1 - 2.9e-72 242.1 3.8 3.8e-72 241.8 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85509.1 - 0.064 13.6 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX85510.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX85511.1 - 4.8e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX85511.1 - 0.0058 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX85511.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX85511.1 - 0.098 12.9 2.0 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) fn3_3 PF14686.6 EAX85512.1 - 0.0008 19.1 1.3 0.039 13.7 0.0 3.5 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II PKD PF00801.20 EAX85512.1 - 0.049 13.5 0.7 0.94 9.4 0.0 3.6 4 1 0 4 4 4 0 PKD domain Spc7_C2 PF15577.6 EAX85512.1 - 0.13 12.3 0.8 1.4 9.0 0.1 2.9 2 0 0 2 2 2 0 Spc7_C2 DUF4446 PF14584.6 EAX85512.1 - 0.19 11.7 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CBM-like PF14683.6 EAX85512.1 - 2.6 7.9 8.1 18 5.2 0.1 4.0 2 1 3 5 5 5 0 Polysaccharide lyase family 4, domain III CHASE3 PF05227.13 EAX85514.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX85514.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) Ank_2 PF12796.7 EAX85515.1 - 3.1e-55 184.7 35.9 2.8e-15 56.7 1.9 5.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85515.1 - 4.2e-42 142.0 14.0 5.6e-10 39.5 0.1 7.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX85515.1 - 6.2e-42 141.4 5.9 6.2e-42 141.4 5.9 3.7 3 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX85515.1 - 7.1e-32 108.4 7.7 1.9e-06 28.0 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAX85515.1 - 9e-30 99.4 10.1 1.5e-05 25.0 0.0 8.5 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX85515.1 - 6.9e-28 96.3 17.0 2.7e-12 46.6 0.4 5.9 4 2 5 9 9 9 6 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX85515.1 - 0.0007 19.7 10.3 3.3 7.9 0.2 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3718) CCDC84 PF14968.6 EAX85515.1 - 0.72 9.4 4.6 20 4.7 0.1 3.1 1 1 2 3 3 3 0 Coiled coil protein 84 DUF4107 PF13389.6 EAX85518.1 - 1.9e-71 239.4 3.6 2.9e-71 238.8 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85519.1 - 1.4e-152 506.0 13.0 1.7e-152 505.8 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85519.1 - 1.6 9.3 7.0 1.5 9.4 1.1 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX85520.1 - 0.005 16.8 7.4 0.0077 16.2 7.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF2897 PF11446.8 EAX85522.1 - 2.5 8.0 4.3 5.4 7.0 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX85523.1 - 5.6e-63 211.2 6.0 6.2e-63 211.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) F5_F8_type_C PF00754.25 EAX85524.1 - 6.6e-08 32.7 0.0 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 2 F5/8 type C domain GAS2 PF02187.17 EAX85524.1 - 0.045 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain SAS-6_N PF16531.5 EAX85525.1 - 6.9e-19 68.2 3.3 1.4e-18 67.3 3.3 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal SeqA PF03925.13 EAX85525.1 - 0.019 14.9 0.4 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 SeqA protein C-terminal domain DUSP PF06337.12 EAX85525.1 - 0.12 13.0 0.4 0.23 12.1 0.1 1.8 1 1 1 2 2 2 0 DUSP domain DUF501 PF04417.12 EAX85526.1 - 0.69 9.7 4.8 0.87 9.4 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF501) Metallophos PF00149.28 EAX85527.1 - 8.2e-28 98.3 0.8 1.1e-27 97.9 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX85527.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FAM217 PF15344.6 EAX85528.1 - 0.21 11.5 20.5 0.45 10.4 20.5 1.5 1 0 0 1 1 1 0 FAM217 family CDC27 PF09507.10 EAX85528.1 - 2.6 7.4 39.3 3 7.1 39.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Apolipoprotein PF01442.18 EAX85529.1 - 0.00093 19.1 10.6 0.15 11.9 0.6 3.8 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 EAX85529.1 - 0.0025 17.4 25.4 0.092 12.3 6.2 4.2 2 2 2 4 4 4 2 Domain of unknown function (DUF4795) Phasin PF05597.11 EAX85529.1 - 0.02 14.9 0.6 0.02 14.9 0.6 3.8 4 1 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 EAX85529.1 - 0.027 14.5 19.8 0.072 13.1 1.9 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EAX85529.1 - 0.059 12.7 7.9 1.5 8.1 7.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SF1-HH PF16275.5 EAX85529.1 - 0.066 13.6 3.6 0.27 11.6 0.1 3.4 4 0 0 4 4 4 0 Splicing factor 1 helix-hairpin domain OrfB_IS605 PF01385.19 EAX85529.1 - 0.14 12.4 1.3 0.33 11.2 0.2 2.2 2 0 0 2 2 2 0 Probable transposase GvpG PF05120.12 EAX85529.1 - 0.15 12.1 1.1 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Gas vesicle protein G Baculo_PEP_C PF04513.12 EAX85529.1 - 0.19 11.7 18.8 0.26 11.3 1.7 4.3 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapD PF07072.11 EAX85529.1 - 0.43 10.3 8.2 4.5 7.0 0.3 3.4 2 1 0 3 3 3 0 Cell division protein TolA_bind_tri PF16331.5 EAX85529.1 - 0.46 10.6 5.7 24 5.1 0.9 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation ApoLp-III PF07464.11 EAX85529.1 - 0.49 10.5 21.3 0.99 9.5 1.8 3.8 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Syntaxin-6_N PF09177.11 EAX85529.1 - 0.74 10.4 14.4 1.3e+02 3.2 14.4 3.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Prominin PF05478.11 EAX85529.1 - 0.81 7.6 17.2 0.89 7.4 2.7 2.2 1 1 0 2 2 2 0 Prominin Med9 PF07544.13 EAX85529.1 - 0.87 9.7 15.0 0.25 11.4 0.4 4.6 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Arg_decarbox_C PF17944.1 EAX85529.1 - 0.9 10.1 3.8 1.1 9.8 0.2 3.1 4 0 0 4 4 1 0 Arginine decarboxylase C-terminal helical extension ABC_tran_CTD PF16326.5 EAX85529.1 - 0.94 9.8 8.4 8 6.8 0.2 3.8 5 0 0 5 5 3 0 ABC transporter C-terminal domain AI-2E_transport PF01594.16 EAX85529.1 - 0.97 8.5 1.6 3.8 6.6 0.1 2.4 1 1 1 2 2 2 0 AI-2E family transporter Bap31_Bap29_C PF18035.1 EAX85529.1 - 1.1 9.3 5.5 12 6.0 0.3 3.0 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain SlyX PF04102.12 EAX85529.1 - 1.4 9.6 10.2 15 6.3 0.3 4.4 4 1 0 4 4 3 0 SlyX T3SSipB PF16535.5 EAX85529.1 - 1.8 9.0 8.4 3.1 8.3 0.7 3.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB CLZ PF16526.5 EAX85529.1 - 1.8 9.0 14.5 6.3 7.2 0.1 4.7 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HalX PF08663.10 EAX85529.1 - 2 8.8 3.8 47 4.4 0.0 3.7 4 0 0 4 4 3 0 HalX domain DNA_primase_lrg PF04104.14 EAX85529.1 - 2.7 7.3 7.3 0.6 9.5 0.5 2.7 2 2 1 3 3 3 0 Eukaryotic and archaeal DNA primase, large subunit Uds1 PF15456.6 EAX85529.1 - 2.8 8.1 7.6 3.7 7.7 4.1 2.9 1 1 1 2 2 2 0 Up-regulated During Septation Cep57_CLD_2 PF14197.6 EAX85529.1 - 2.9 8.0 8.9 7.1 6.8 0.5 4.2 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF745 PF05335.13 EAX85529.1 - 3.4 7.3 8.6 2.1 8.0 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 EAX85529.1 - 3.4 7.8 16.5 0.78 9.9 1.2 3.4 3 1 0 3 3 3 0 Tropomyosin like DUF5082 PF16888.5 EAX85529.1 - 5.2 7.4 22.1 3.4 7.9 4.9 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) Tmpp129 PF10272.9 EAX85529.1 - 6.4 6.0 6.2 1.3 8.2 1.9 1.8 2 0 0 2 2 2 0 Putative transmembrane protein precursor Ank_2 PF12796.7 EAX85530.1 - 5.2e-64 212.8 15.5 1.8e-17 63.7 0.2 4.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85530.1 - 1.1e-36 124.7 0.1 3.2e-08 33.9 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX85530.1 - 4.5e-33 112.2 0.1 8.2e-07 29.2 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX85530.1 - 7.8e-33 112.1 8.5 6e-09 36.0 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85530.1 - 3.5e-30 100.7 0.0 0.00013 22.1 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ribosomal_L29 PF00831.23 EAX85530.1 - 0.0055 16.6 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal L29 protein DivIC PF04977.15 EAX85530.1 - 0.047 13.5 2.1 0.17 11.7 2.1 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF724 PF05266.14 EAX85530.1 - 0.073 12.9 5.3 0.14 12.0 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 EAX85530.1 - 0.077 13.2 5.2 0.17 12.0 5.2 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF1910 PF08928.10 EAX85530.1 - 0.097 12.7 4.9 0.23 11.5 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Glycos_transf_N PF04413.16 EAX85530.1 - 0.17 11.5 0.0 21 4.7 0.0 2.5 3 0 0 3 3 3 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) YabA PF06156.13 EAX85530.1 - 0.28 11.9 4.0 1 10.1 4.0 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Ndc80_HEC PF03801.13 EAX85530.1 - 0.33 10.6 5.6 1.3 8.7 2.6 2.9 2 1 1 3 3 3 0 HEC/Ndc80p family GIT_CC PF16559.5 EAX85530.1 - 5 7.1 9.9 7.6 6.5 1.7 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF720 PF05302.11 EAX85530.1 - 5.2 6.9 12.8 0.59 10.0 6.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF720) TMP PF05017.14 EAX85531.1 - 0.078 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85532.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Nup35_RRM_2 PF14605.6 EAX85534.1 - 0.0011 18.9 0.3 0.0026 17.7 0.3 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EAX85534.1 - 0.0013 18.5 1.9 0.0013 18.5 0.2 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFP PF01353.22 EAX85534.1 - 0.0013 18.2 0.4 0.0028 17.2 0.4 1.5 1 0 0 1 1 1 1 Green fluorescent protein DUF3921 PF13060.6 EAX85534.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Ank_4 PF13637.6 EAX85535.1 - 4.7e-23 81.3 0.0 2.4e-08 34.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX85535.1 - 2.1e-20 73.1 0.0 1.1e-08 35.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85535.1 - 2.3e-15 55.2 0.0 0.0012 19.1 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX85535.1 - 5.7e-12 45.6 0.5 0.0019 18.5 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX85535.1 - 9.3e-12 44.8 0.0 0.014 15.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF249 PF03158.13 EAX85535.1 - 0.014 15.1 0.0 0.08 12.6 0.0 1.9 2 0 0 2 2 2 0 Multigene family 530 protein B277 PF17623.2 EAX85536.1 - 8.7 5.3 11.9 1 8.4 7.2 1.7 2 0 0 2 2 2 0 Domain of unknown function YabA PF06156.13 EAX85536.1 - 9 7.0 11.6 1 10.1 5.6 2.1 2 1 0 2 2 2 0 Initiation control protein YabA DUF5603 PF18231.1 EAX85537.1 - 0.13 12.5 2.1 24 5.3 0.0 3.3 3 2 0 3 3 3 0 Domain of unknown function (DUF5603) Pox_A32 PF04665.12 EAX85538.1 - 1.7e-07 31.0 3.2 2.5e-07 30.4 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85538.1 - 0.0032 17.1 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX85538.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX85538.1 - 0.062 13.0 0.1 0.32 10.7 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX85538.1 - 0.08 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX85538.1 - 0.41 10.9 8.5 5.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Ribosomal_L24e PF01246.20 EAX85539.1 - 2.3e-22 79.0 1.5 2.3e-22 79.0 1.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Lipase_3 PF01764.25 EAX85540.1 - 3.7e-15 56.0 0.0 6.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EAX85540.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX85540.1 - 0.038 14.6 0.0 0.049 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EAX85540.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EAX85540.1 - 0.14 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 EAX85540.1 - 0.15 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PG_isomerase_N PF18353.1 EAX85541.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain DUF4106 PF13388.6 EAX85542.1 - 5e-275 912.1 17.9 8.6e-275 911.4 17.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX85542.1 - 0.039 14.3 0.1 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated ArsC PF03960.15 EAX85543.1 - 0.091 12.8 0.9 0.16 12.0 0.9 1.5 1 1 0 1 1 1 0 ArsC family LRR_5 PF13306.6 EAX85544.1 - 1e-53 180.7 26.0 4.5e-26 91.3 13.9 4.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85544.1 - 2.3e-09 36.9 0.0 0.21 11.4 0.0 5.3 2 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EAX85544.1 - 0.0045 17.4 1.1 4.8 7.8 0.0 4.3 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) PSP PF04046.16 EAX85545.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85546.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Mem_trans PF03547.18 EAX85547.1 - 1.2e-14 53.6 19.8 2.8e-12 45.8 10.1 2.0 1 1 1 2 2 2 2 Membrane transport protein Orthoreo_P10 PF07204.11 EAX85547.1 - 0.031 14.2 0.7 0.08 12.9 0.7 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF563 PF04577.14 EAX85548.1 - 2.3e-34 119.4 1.1 3.7e-34 118.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LRR_4 PF12799.7 EAX85549.1 - 1.2e-12 47.8 4.4 1.1e-06 28.9 2.8 3.2 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX85549.1 - 1.5e-10 40.9 1.6 4.6e-10 39.3 1.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAX85549.1 - 5.9e-08 32.4 3.9 7.9e-06 25.5 3.8 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EAX85549.1 - 0.0082 16.1 1.3 8 6.8 0.2 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EAX85549.1 - 8 7.4 7.1 1e+02 4.1 0.4 4.5 5 1 0 5 5 5 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 EAX85550.1 - 1.2e-39 134.2 5.2 1.8e-12 47.2 0.4 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85550.1 - 1e-36 124.9 7.5 1.7e-15 57.0 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX85550.1 - 4.5e-08 32.9 0.0 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX85550.1 - 0.00055 19.9 0.5 0.83 9.7 0.0 3.6 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX85550.1 - 0.016 15.4 1.4 0.079 13.1 0.0 2.9 3 1 1 4 4 4 0 Rap1 Myb domain Spore_III_AB PF09548.10 EAX85550.1 - 0.029 14.5 0.1 7.3 6.7 0.0 3.2 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EAX85550.1 - 0.47 10.9 7.0 3.5 8.1 0.1 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4108 PF13390.6 EAX85553.1 - 3.1e-64 215.2 5.5 3.5e-64 215.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Transposase_mut PF00872.18 EAX85555.1 - 0.0035 16.2 0.6 0.0052 15.7 0.3 1.4 1 1 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX85555.1 - 0.026 14.5 0.3 0.04 13.9 0.3 1.3 1 0 0 1 1 1 0 Vta1 like DUF3839 PF12943.7 EAX85557.1 - 4.9e-151 501.0 11.0 6.8e-151 500.5 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX85557.1 - 0.0073 16.8 0.3 0.048 14.2 0.1 2.5 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX85557.1 - 0.015 15.8 1.3 0.06 13.8 0.1 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX85557.1 - 0.14 12.5 0.5 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Lectin_legB PF00139.19 EAX85557.1 - 0.27 10.7 1.4 7.1 6.1 0.2 2.2 2 0 0 2 2 2 0 Legume lectin domain KELK PF15796.5 EAX85557.1 - 0.69 10.4 4.5 3 8.4 0.4 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX85558.1 - 3.8e-74 244.7 60.8 7.7e-31 105.9 17.4 6.3 4 2 2 6 6 6 3 Phage tail repeat like Peptidase_C78 PF07910.13 EAX85558.1 - 0.013 15.0 5.5 2.7 7.4 0.5 3.7 1 1 2 3 3 3 0 Peptidase family C78 Apolipoprotein PF01442.18 EAX85558.1 - 0.013 15.4 2.7 0.023 14.6 2.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX85558.1 - 0.044 13.5 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX85558.1 - 0.26 10.7 8.3 1.4 8.3 1.0 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX85558.1 - 0.28 11.5 13.6 22 5.5 0.2 5.6 1 1 5 6 6 6 0 TFIIH p62 subunit, N-terminal domain KilA-N PF04383.13 EAX85559.1 - 3.1e-43 146.1 0.5 6.6e-43 145.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85559.1 - 0.0055 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family DUF3447 PF11929.8 EAX85560.1 - 3.9e-38 129.3 15.7 2.6e-37 126.6 5.9 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX85560.1 - 6.4e-29 100.4 8.8 9.8e-15 54.9 0.7 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85560.1 - 1.1e-22 80.1 5.3 2.6e-09 37.4 0.0 5.8 2 2 5 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX85560.1 - 2.1e-20 72.2 0.1 2.9e-06 27.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX85560.1 - 1.9e-18 64.6 5.9 0.0011 19.3 0.1 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX85560.1 - 8.2e-18 64.2 0.7 2.3e-09 37.3 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) CCDC84 PF14968.6 EAX85560.1 - 0.031 13.9 0.3 0.058 13.0 0.3 1.5 1 1 0 1 1 1 0 Coiled coil protein 84 RL PF17797.1 EAX85560.1 - 1.9 8.5 5.5 25 4.9 0.3 3.3 3 1 0 3 3 3 0 RL domain Ank_4 PF13637.6 EAX85562.1 - 1.8e-20 73.0 1.9 1.1e-11 44.9 0.1 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX85562.1 - 1e-19 70.0 1.6 3.8e-08 33.4 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX85562.1 - 9.5e-18 64.0 0.4 4.4e-10 39.6 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX85562.1 - 1.3e-17 64.2 0.1 1.7e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85562.1 - 2.2e-17 61.3 2.1 3.5e-07 30.0 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat DUF3447 PF11929.8 EAX85562.1 - 0.26 11.3 7.5 2.8 8.0 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DAG1 PF05454.11 EAX85564.1 - 0.0016 17.9 0.1 0.0021 17.5 0.1 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) PRIMA1 PF16101.5 EAX85564.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ETRAMP PF09716.10 EAX85564.1 - 0.041 13.9 3.3 0.061 13.4 3.3 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Fusion_gly PF00523.18 EAX85564.1 - 1.3 7.2 5.7 0.96 7.6 4.6 1.3 1 1 0 1 1 1 0 Fusion glycoprotein F0 Trypan_PARP PF05887.11 EAX85566.1 - 0.054 13.5 13.6 0.057 13.4 13.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX85568.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) HECW_N PF16562.5 EAX85570.1 - 0.017 14.9 0.7 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Collagen_bind_2 PF12904.7 EAX85571.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase GPS2_interact PF15784.5 EAX85572.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85572.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain LysM PF01476.20 EAX85574.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 LysM domain BRCT_2 PF16589.5 EAX85575.1 - 5.1e-20 71.7 0.1 9.3e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EAX85575.1 - 1e-08 35.4 0.1 2.2e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EAX85575.1 - 1.6e-05 24.7 0.1 3.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EAX85575.1 - 0.0046 17.2 0.4 0.0046 17.2 0.4 2.1 2 1 0 2 2 2 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EAX85575.1 - 0.015 15.2 0.4 0.058 13.3 0.1 2.1 2 1 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Guanylate_cyc PF00211.20 EAX85576.1 - 2.8e-35 121.6 0.0 7.8e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ETRAMP PF09716.10 EAX85576.1 - 0.012 15.7 0.8 1.5 8.9 0.0 4.0 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) HNOBA PF07701.14 EAX85576.1 - 0.049 13.0 0.3 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Heme NO binding associated PAS_9 PF13426.7 EAX85576.1 - 0.054 13.7 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 EAX85576.1 - 0.17 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold Myb_DNA-binding PF00249.31 EAX85577.1 - 2e-30 104.7 3.7 1.1e-17 63.9 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85577.1 - 9.1e-22 77.1 1.5 1.2e-12 47.9 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85577.1 - 0.00055 19.9 0.1 0.013 15.6 0.0 2.2 1 1 1 2 2 2 1 SLIDE Rap1_C PF11626.8 EAX85577.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX85577.1 - 0.068 13.5 4.1 11 6.4 1.4 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX85577.1 - 0.11 12.4 0.2 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX85577.1 - 0.12 12.6 1.2 0.44 10.8 0.2 2.4 1 1 1 2 2 2 0 Rap1 Myb domain Ribosomal_S4 PF00163.19 EAX85578.1 - 7.3e-07 30.0 0.6 1.5e-06 29.0 0.6 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EAX85578.1 - 1.1e-06 28.3 0.1 2.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 S4 domain His_Phos_2 PF00328.22 EAX85579.1 - 1.2e-14 54.5 2.6 2.5e-10 40.3 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) Thioredoxin PF00085.20 EAX85580.1 - 0.0056 16.6 0.1 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin PSP PF04046.16 EAX85581.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85582.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85583.1 - 0.075 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX85584.1 - 4.7e-156 517.4 14.7 5.8e-156 517.1 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX85584.1 - 0.34 11.2 1.7 0.97 9.8 0.5 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX85584.1 - 0.54 10.8 5.5 1.9 9.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85584.1 - 0.75 10.3 8.8 2.9 8.4 1.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX85585.1 - 7.4e-06 26.4 0.7 2.1e-05 25.0 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX85585.1 - 0.0044 16.6 0.3 0.52 9.8 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain Baculo_ME53 PF06061.11 EAX85585.1 - 0.0055 16.0 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 Baculoviridae ME53 Trypan_PARP PF05887.11 EAX85588.1 - 0.07 13.1 12.8 0.072 13.1 12.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85588.1 - 3 8.3 6.3 3.3 8.2 6.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Maf1 PF09174.10 EAX85590.1 - 2.8e-31 109.0 0.8 3.7e-31 108.6 0.8 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF4106 PF13388.6 EAX85591.1 - 2e-274 910.1 20.8 3e-274 909.6 20.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX85591.1 - 0.017 15.4 0.1 0.8 10.0 0.2 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated WYL_3 PF18488.1 EAX85591.1 - 1.9 8.9 7.2 10 6.6 0.4 3.2 3 0 0 3 3 3 0 WYL domain Myb_DNA-binding PF00249.31 EAX85593.1 - 2e-29 101.5 2.5 9.5e-15 54.5 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85593.1 - 3e-21 75.4 4.6 7.4e-13 48.5 0.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85593.1 - 8.9e-05 22.5 0.1 0.017 15.1 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX85593.1 - 0.0034 17.5 0.8 0.32 11.2 0.1 2.9 3 1 0 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX85593.1 - 0.012 16.0 0.9 0.51 10.8 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Acetone_carb_G PF08882.11 EAX85593.1 - 0.034 14.3 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Myb_DNA-bind_5 PF13873.6 EAX85593.1 - 1.5 8.9 5.3 44 4.3 0.1 3.5 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Chromo PF00385.24 EAX85594.1 - 1.2e-16 60.3 3.7 4.6e-16 58.5 0.3 2.4 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAX85594.1 - 1.5e-11 44.2 0.2 3e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain EF-hand_10 PF14788.6 EAX85595.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF3839 PF12943.7 EAX85597.1 - 7e-154 510.3 12.2 8.7e-154 510.0 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85597.1 - 0.057 13.9 1.4 0.26 11.7 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX85597.1 - 0.86 10.1 4.6 12 6.5 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX85597.1 - 4.3 7.7 7.0 12 6.2 0.1 3.6 3 2 2 5 5 5 0 Tup N-terminal Amidase02_C PF12123.8 EAX85598.1 - 0.0023 17.6 0.0 0.0066 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX85598.1 - 0.19 11.6 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) MAP65_ASE1 PF03999.12 EAX85599.1 - 4.2e-33 114.9 12.5 5e-33 114.7 12.5 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Bap31_Bap29_C PF18035.1 EAX85599.1 - 0.002 18.1 1.8 0.002 18.1 1.8 4.0 3 1 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain BCDHK_Adom3 PF10436.9 EAX85599.1 - 0.018 14.8 0.7 0.044 13.6 0.7 1.7 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF760 PF05542.11 EAX85599.1 - 0.065 13.6 0.2 0.38 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DnaI_N PF07319.11 EAX85599.1 - 0.11 13.2 3.0 0.64 10.7 0.2 2.9 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus LMBR1 PF04791.16 EAX85599.1 - 0.28 10.0 4.6 0.7 8.7 4.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.13 EAX85599.1 - 1.6 7.3 3.4 1.3 7.6 0.3 1.9 2 0 0 2 2 2 0 Tweety Apolipoprotein PF01442.18 EAX85599.1 - 1.7 8.5 10.8 2.6 7.9 0.1 3.1 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF4404 PF14357.6 EAX85599.1 - 2.6 8.8 10.5 0.88 10.2 1.9 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) LRR_5 PF13306.6 EAX85600.1 - 3.7e-54 182.1 42.2 5.5e-21 74.9 15.6 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85600.1 - 9e-14 51.0 2.6 0.11 12.3 0.0 6.0 3 2 6 9 9 9 8 Leucine rich repeat DUF3450 PF11932.8 EAX85601.1 - 4.6e-06 26.1 14.1 4.6e-06 26.1 14.1 6.3 2 2 3 6 6 6 2 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EAX85601.1 - 0.00019 21.5 75.2 0.00024 21.1 3.8 7.6 4 1 4 8 8 8 4 Protein of unknown function (DUF1664) MAD PF05557.13 EAX85601.1 - 0.00023 19.7 43.9 0.00023 19.7 43.9 3.4 2 1 1 3 3 3 1 Mitotic checkpoint protein TPD52 PF04201.15 EAX85601.1 - 0.002 17.7 4.7 0.002 17.7 4.7 6.4 2 2 5 7 7 7 1 Tumour protein D52 family TPR_MLP1_2 PF07926.12 EAX85601.1 - 0.0035 17.4 22.4 0.0035 17.4 22.4 6.4 2 2 5 7 7 6 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EAX85601.1 - 0.0043 16.0 106.1 0.0089 14.9 16.9 5.2 2 2 4 6 6 6 5 Spc7 kinetochore protein FliJ PF02050.16 EAX85601.1 - 0.013 15.7 10.2 0.013 15.7 10.2 5.7 4 2 2 6 6 6 0 Flagellar FliJ protein Fez1 PF06818.15 EAX85601.1 - 0.12 12.8 92.3 0.14 12.5 13.9 5.1 2 2 3 5 5 5 0 Fez1 Golgin_A5 PF09787.9 EAX85601.1 - 0.43 10.0 101.6 0.011 15.2 32.4 4.0 2 2 1 3 3 3 0 Golgin subfamily A member 5 CALCOCO1 PF07888.11 EAX85601.1 - 0.95 8.2 87.1 0.023 13.6 10.9 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 EAX85601.1 - 3.7 7.3 95.4 0.11 12.3 25.0 5.1 2 2 3 5 5 5 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EAX85601.1 - 5.2 7.1 108.4 1.7 8.7 14.5 5.4 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF3839 PF12943.7 EAX85602.1 - 1.5e-160 532.1 13.6 1.9e-160 531.8 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX85602.1 - 0.048 13.9 0.7 0.1 12.8 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX85602.1 - 1.5 9.4 7.2 2.1 8.8 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase EF-hand_7 PF13499.6 EAX85603.1 - 1.8e-23 82.8 2.3 7.3e-13 48.8 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAX85603.1 - 8.1e-18 64.0 2.2 5.7e-08 32.5 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAX85603.1 - 1.4e-16 58.9 6.1 3e-07 29.8 0.2 4.7 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EAX85603.1 - 2.6e-16 57.9 11.3 7.5e-07 28.3 0.8 4.2 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 EAX85603.1 - 1.7e-05 24.1 9.2 0.01 15.3 0.6 3.8 3 1 1 4 4 4 2 EF hand EF-hand_4 PF12763.7 EAX85603.1 - 6.3e-05 22.9 0.4 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EAX85603.1 - 0.00091 19.5 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 EAX85603.1 - 0.021 14.9 0.2 0.79 9.9 0.1 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RNaseH_C PF09293.10 EAX85603.1 - 0.093 13.1 0.2 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 T4 RNase H, C terminal DUF3349 PF11829.8 EAX85603.1 - 0.095 13.5 0.3 4.5 8.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) SPARC_Ca_bdg PF10591.9 EAX85603.1 - 0.1 12.9 0.0 2.8 8.3 0.0 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EAX85603.1 - 0.23 11.7 2.1 19 5.5 0.3 2.6 2 2 0 2 2 2 0 Dockerin type I domain Apolipoprotein PF01442.18 EAX85604.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PSP PF04046.16 EAX85605.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85606.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85607.1 - 0.077 13.5 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX85608.1 - 1.2e-156 519.3 14.6 1.5e-156 519.0 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX85608.1 - 0.15 12.7 5.4 0.92 10.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85608.1 - 0.31 11.5 7.4 2.1 8.9 0.9 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX85608.1 - 0.98 10.1 0.1 0.98 10.1 0.1 3.0 2 2 2 4 4 4 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX85609.1 - 4.3e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX85609.1 - 0.015 14.7 0.5 0.028 13.8 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX85610.1 - 4.4e-119 396.3 7.5 5.1e-119 396.1 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MFS_2 PF13347.6 EAX85611.1 - 5.7e-37 127.3 15.8 6.2e-37 127.2 15.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EAX85611.1 - 7.3e-11 41.6 15.3 1.6e-10 40.4 13.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Ndc1_Nup PF09531.10 EAX85611.1 - 0.0064 15.2 0.2 0.0064 15.2 0.2 2.6 1 1 0 2 2 2 1 Nucleoporin protein Ndc1-Nup MFS_1_like PF12832.7 EAX85611.1 - 0.1 11.4 12.8 0.093 11.6 10.9 1.9 1 1 1 2 2 2 0 MFS_1 like family UPF0242 PF06785.11 EAX85611.1 - 3.5 7.7 5.5 4.6 7.3 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 EAX85612.1 - 0.00045 19.9 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Glyco_transf_49 PF13896.6 EAX85612.1 - 0.0065 15.9 0.1 0.0095 15.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Phage_fiber PF03335.13 EAX85612.1 - 0.45 10.8 9.8 0.22 11.8 1.9 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX85612.1 - 0.46 11.1 2.9 4.8 7.8 0.2 2.2 1 1 1 2 2 2 0 YmaF family Gly-zipper_Omp PF13488.6 EAX85613.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX85613.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Ank_2 PF12796.7 EAX85614.1 - 1.8e-19 70.1 0.5 9.5e-07 29.3 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX85614.1 - 1.4e-15 57.1 0.5 9.7e-08 32.1 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX85614.1 - 4e-12 46.0 0.1 0.013 15.9 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX85614.1 - 7.2e-12 45.6 0.2 0.00051 20.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85614.1 - 9.5e-12 44.0 0.4 0.18 12.5 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat NMT_C PF02799.15 EAX85614.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain GPS2_interact PF15784.5 EAX85615.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85615.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85616.1 - 0.071 13.1 11.2 0.1 12.6 11.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 EAX85617.1 - 1.1e-67 228.2 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85617.1 - 2.4e-39 135.2 0.0 3.1e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85617.1 - 3.6e-07 29.8 0.0 9.4e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX85617.1 - 5.7e-06 25.5 0.1 8.3e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX85617.1 - 0.0027 17.6 0.1 0.76 9.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF3232 PF11554.8 EAX85617.1 - 0.0042 17.5 0.5 0.0084 16.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) Choline_kinase PF01633.20 EAX85617.1 - 0.018 14.6 0.8 0.031 13.9 0.5 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase zf-DNA_Pol PF08996.10 EAX85618.1 - 0.95 9.2 5.8 0.21 11.3 1.2 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Nitroreductase PF00881.24 EAX85619.1 - 8e-29 100.9 0.0 9.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX85619.1 - 1.5e-05 24.7 0.1 0.0018 17.9 0.2 2.3 1 1 1 2 2 2 2 Putative TM nitroreductase DUF3839 PF12943.7 EAX85620.1 - 2.8e-153 508.3 12.6 3.6e-153 508.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85620.1 - 0.023 15.1 2.4 0.094 13.2 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX85620.1 - 0.41 11.1 7.7 0.77 10.3 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX85621.1 - 6.7e-07 29.0 2.7 6.7e-07 29.0 2.7 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85621.1 - 0.0001 22.6 0.1 0.00072 19.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX85621.1 - 0.00025 21.1 3.0 0.0006 19.9 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX85621.1 - 0.00031 20.5 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX85621.1 - 0.00097 19.0 0.1 0.002 17.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX85621.1 - 0.0015 18.2 0.5 0.0087 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX85621.1 - 0.013 15.3 0.7 0.025 14.4 0.7 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX85621.1 - 0.031 14.6 0.0 0.061 13.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX85621.1 - 0.062 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.29 EAX85621.1 - 0.13 12.7 0.1 0.86 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2897 PF11446.8 EAX85622.1 - 1.8 8.5 3.7 3.9 7.4 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX85623.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX85624.1 - 2.8e-05 24.5 2.0 0.00012 22.5 2.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX85624.1 - 0.034 13.2 0.8 0.046 12.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX85624.1 - 0.067 13.8 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3839 PF12943.7 EAX85625.1 - 1.4e-114 381.6 6.4 1.7e-114 381.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX85627.1 - 0.12 12.3 9.1 0.15 12.1 9.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85627.1 - 0.68 10.4 5.2 0.77 10.2 5.2 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX85628.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85628.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX85631.1 - 1.4e-148 492.9 12.0 2e-148 492.4 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX85631.1 - 0.0011 19.5 0.6 0.074 13.6 0.2 3.3 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX85631.1 - 0.0063 17.0 1.2 0.029 14.8 0.1 2.0 2 0 0 2 2 2 1 Fez1 Lectin_legB PF00139.19 EAX85631.1 - 0.14 11.7 1.4 0.32 10.5 0.3 1.9 2 0 0 2 2 2 0 Legume lectin domain Rx_N PF18052.1 EAX85631.1 - 0.48 10.7 3.1 2.1 8.7 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX85631.1 - 0.79 10.2 5.9 1.9 9.0 1.0 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LRR_5 PF13306.6 EAX85632.1 - 5.5e-16 58.7 7.3 1.3e-15 57.5 2.8 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85632.1 - 0.0047 16.7 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Leucine rich repeat DUF4834 PF16118.5 EAX85633.1 - 3.2e-05 24.8 1.7 0.00014 22.7 1.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) MMM1 PF10296.9 EAX85633.1 - 0.00032 19.9 2.0 0.00054 19.1 2.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SID-1_RNA_chan PF13965.6 EAX85633.1 - 0.00032 19.3 1.2 0.00051 18.6 1.2 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Amnionless PF14828.6 EAX85633.1 - 0.00059 18.8 0.3 0.0011 17.9 0.3 1.3 1 0 0 1 1 1 1 Amnionless Tmemb_9 PF05434.11 EAX85633.1 - 0.00072 19.5 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 TMEM9 SpoIIIAH PF12685.7 EAX85633.1 - 0.00091 19.1 6.6 0.0025 17.7 6.6 1.7 1 0 0 1 1 1 1 SpoIIIAH-like protein EphA2_TM PF14575.6 EAX85633.1 - 0.00092 20.0 0.7 0.0035 18.2 0.7 2.1 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain V_ATPase_I PF01496.19 EAX85633.1 - 0.0013 16.8 4.0 0.0022 16.0 4.0 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4199 PF13858.6 EAX85633.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) VSP PF03302.13 EAX85633.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Protocadherin PF08374.11 EAX85633.1 - 0.0024 17.9 2.3 0.0045 17.0 2.3 1.4 1 0 0 1 1 1 1 Protocadherin FAM176 PF14851.6 EAX85633.1 - 0.0025 17.5 1.8 0.0058 16.3 1.8 1.6 1 0 0 1 1 1 1 FAM176 family MAP17 PF15807.5 EAX85633.1 - 0.0034 17.6 6.1 0.0086 16.3 6.1 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 EAX85633.1 - 0.0037 17.6 0.2 0.0074 16.6 0.2 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CLN3 PF02487.17 EAX85633.1 - 0.0037 16.4 2.5 0.0061 15.7 2.5 1.3 1 0 0 1 1 1 1 CLN3 protein Coilin_N PF15862.5 EAX85633.1 - 0.0046 16.8 9.7 0.0046 16.8 9.7 1.9 2 0 0 2 2 1 1 Coilin N-terminus O-antigen_lig PF13425.6 EAX85633.1 - 0.0066 15.3 4.2 0.011 14.6 4.2 1.3 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF4446 PF14584.6 EAX85633.1 - 0.0093 16.0 1.7 0.02 14.9 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Serinc PF03348.15 EAX85633.1 - 0.0097 14.9 1.2 0.019 13.9 1.2 1.4 1 0 0 1 1 1 1 Serine incorporator (Serinc) Connexin PF00029.19 EAX85633.1 - 0.013 15.3 3.2 0.026 14.3 3.2 1.4 1 0 0 1 1 1 0 Connexin UPF0242 PF06785.11 EAX85633.1 - 0.016 15.3 2.3 0.026 14.6 2.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OSTbeta PF15048.6 EAX85633.1 - 0.017 15.3 4.8 0.053 13.7 4.8 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4690 PF15756.5 EAX85633.1 - 0.018 15.6 0.9 0.018 15.6 0.9 2.2 2 0 0 2 2 1 0 Small Novel Rich in Cartilage SARAF PF06682.12 EAX85633.1 - 0.021 14.5 0.5 0.037 13.7 0.5 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DAP10 PF07213.11 EAX85633.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein FAM163 PF15069.6 EAX85633.1 - 0.04 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 FAM163 family HemX PF04375.14 EAX85633.1 - 0.042 13.1 0.2 0.066 12.5 0.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase RNA_pol_Rpc4 PF05132.14 EAX85633.1 - 0.044 14.2 4.0 0.096 13.1 4.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Syndecan PF01034.20 EAX85633.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Syndecan domain DUF2615 PF11027.8 EAX85633.1 - 0.075 13.2 1.2 0.45 10.7 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) CYYR1 PF10873.8 EAX85633.1 - 0.094 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MBD PF01429.19 EAX85633.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Methyl-CpG binding domain SIT PF15330.6 EAX85633.1 - 0.11 13.0 3.7 0.35 11.3 3.7 2.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEMspv1-c74-12 PF11044.8 EAX85633.1 - 0.13 12.3 0.6 0.52 10.3 0.6 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Phage_Gp23 PF10669.9 EAX85633.1 - 0.14 12.5 6.4 0.35 11.2 6.4 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Nucleoside_tran PF01733.18 EAX85633.1 - 0.18 11.1 0.4 0.46 9.8 0.4 1.6 1 0 0 1 1 1 0 Nucleoside transporter tRNA_anti-like PF12869.7 EAX85633.1 - 0.19 11.3 2.5 0.63 9.6 2.5 1.9 1 1 0 1 1 1 0 tRNA_anti-like DUF1980 PF09323.10 EAX85633.1 - 0.23 11.4 4.8 0.065 13.1 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Folate_carrier PF01770.18 EAX85633.1 - 0.24 10.1 0.6 0.38 9.5 0.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Zip PF02535.22 EAX85633.1 - 0.29 10.3 3.3 0.53 9.5 3.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LRR19-TM PF15176.6 EAX85633.1 - 0.3 11.1 3.0 0.49 10.4 0.1 2.6 3 0 0 3 3 2 0 Leucine-rich repeat family 19 TM domain Baculo_11_kDa PF06143.11 EAX85633.1 - 0.31 10.6 3.1 0.25 11.0 0.6 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Conotoxin PF02950.17 EAX85633.1 - 0.38 11.8 3.0 2 9.5 3.0 2.2 1 1 0 1 1 1 0 Conotoxin Chordopox_A13L PF05961.11 EAX85633.1 - 0.43 10.8 3.7 1.1 9.6 2.2 2.7 2 1 0 2 2 1 0 Chordopoxvirus A13L protein CobT PF06213.12 EAX85633.1 - 0.48 9.8 10.8 0.78 9.1 10.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2681 PF10883.8 EAX85633.1 - 0.64 10.5 4.9 0.31 11.5 1.7 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) Peptidase_S49_N PF08496.10 EAX85633.1 - 1.2 9.2 9.8 0.6 10.2 5.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 EAX85633.1 - 2.2 8.9 12.8 0.96 10.1 8.6 2.5 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain DUF4083 PF13314.6 EAX85633.1 - 6.4 6.8 8.5 0.12 12.4 1.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4083) ODV-E18 PF10717.9 EAX85633.1 - 9.5 6.2 9.6 0.1 12.5 0.8 2.3 3 0 0 3 3 1 0 Occlusion-derived virus envelope protein ODV-E18 Aldo_ket_red PF00248.21 EAX85634.1 - 1.1e-48 165.9 0.1 4.5e-48 163.9 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EAX85634.1 - 0.016 15.1 0.1 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Development and cell death domain LRR_5 PF13306.6 EAX85635.1 - 3.6e-09 36.7 1.4 0.00029 20.8 0.2 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF1493 PF07377.12 EAX85636.1 - 0.027 14.9 1.3 0.039 14.4 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX85636.1 - 0.3 11.1 3.8 6.8 6.8 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein T5orf172 PF10544.9 EAX85638.1 - 9.3e-07 29.3 0.2 2.4e-06 28.0 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX85638.1 - 0.0053 16.3 0.1 0.077 12.5 0.0 2.0 2 0 0 2 2 2 1 Legume lectin domain Pox_A32 PF04665.12 EAX85639.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85639.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85639.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85639.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85639.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85639.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85639.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85639.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85639.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85639.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85639.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85639.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX85641.1 - 9.4e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX85641.1 - 0.051 14.2 0.1 0.095 13.3 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX85641.1 - 0.11 12.5 0.4 0.22 11.5 0.3 1.5 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX85643.1 - 7.7e-43 144.9 0.5 1.7e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85643.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX85644.1 - 3.8e-153 507.9 11.9 4.7e-153 507.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85644.1 - 0.23 12.0 4.5 2.2 8.8 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX85646.1 - 0.075 13.5 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX85647.1 - 4.5e-72 241.5 2.8 5.8e-72 241.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85647.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX85648.1 - 0.0098 15.6 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1031 PF06275.11 EAX85649.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Peptidase_C1 PF00112.23 EAX85650.1 - 2.6e-31 109.4 0.9 2.8e-31 109.3 0.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease KilA-N PF04383.13 EAX85651.1 - 8.6e-39 131.9 3.7 1e-38 131.6 1.2 2.4 2 1 0 2 2 2 1 KilA-N domain Trypan_PARP PF05887.11 EAX85652.1 - 0.072 13.1 9.4 0.12 12.4 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX85653.1 - 0.11 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX85653.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX85654.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_Ag35 PF03286.14 EAX85655.1 - 0.88 9.3 5.9 1.4 8.7 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PfUIS3 PF11567.8 EAX85656.1 - 0.013 15.8 0.2 0.013 15.8 0.2 3.4 3 1 1 4 4 4 0 Plasmodium falciparum UIS3 membrane protein DarA_N PF18788.1 EAX85656.1 - 0.026 14.6 0.0 0.22 11.6 0.0 2.3 2 1 0 2 2 2 0 Defence against restriction A N-terminal RNase_E_G PF10150.9 EAX85656.1 - 0.4 10.0 3.4 0.3 10.4 0.3 2.1 1 1 1 2 2 2 0 Ribonuclease E/G family Osmo_CC PF08946.10 EAX85656.1 - 0.62 10.3 2.9 1.7 9.0 0.0 3.0 3 1 0 3 3 3 0 Osmosensory transporter coiled coil Trypan_PARP PF05887.11 EAX85657.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_5 PF13306.6 EAX85658.1 - 2.5e-72 240.8 71.9 2.5e-16 59.8 10.8 6.4 4 1 1 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX85658.1 - 6.7e-05 22.6 9.4 6.5 6.6 0.0 8.9 7 5 5 12 12 12 2 Leucine rich repeat AP4E_app_platf PF14807.6 EAX85658.1 - 0.022 15.1 0.1 0.19 12.1 0.0 2.6 2 1 1 3 3 3 0 Adaptin AP4 complex epsilon appendage platform LRR_5 PF13306.6 EAX85659.1 - 1.6e-08 34.6 15.2 2e-08 34.2 13.0 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) HIM1 PF08732.10 EAX85659.1 - 0.17 11.4 2.3 5.9 6.4 0.6 2.1 1 1 1 2 2 2 0 HIM1 DUF3839 PF12943.7 EAX85660.1 - 4e-79 265.5 11.0 5.1e-79 265.1 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) THOC7 PF05615.13 EAX85660.1 - 0.077 13.3 0.2 0.13 12.6 0.1 1.5 2 0 0 2 2 2 0 Tho complex subunit 7 DUF2408 PF10303.9 EAX85660.1 - 0.096 13.3 0.2 0.17 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX85660.1 - 0.1 12.4 0.8 0.44 10.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Bap31 PF05529.12 EAX85663.1 - 1.8e-05 24.6 2.6 2.5e-05 24.2 2.6 1.4 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region Claudin_2 PF13903.6 EAX85663.1 - 0.00045 20.0 2.5 0.0013 18.5 0.8 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction LapA_dom PF06305.11 EAX85663.1 - 0.098 12.5 4.2 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LrgA PF03788.14 EAX85663.1 - 0.23 11.4 3.5 0.088 12.8 0.8 1.6 2 0 0 2 2 2 0 LrgA family Herpes_LMP1 PF05297.11 EAX85663.1 - 0.81 8.8 6.0 0.15 11.2 2.3 1.6 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Zip PF02535.22 EAX85663.1 - 3.2 6.9 5.4 12 5.0 2.7 2.3 1 1 1 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EAX85664.1 - 0.00064 19.6 2.6 0.00064 19.6 2.6 1.8 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 EAX85664.1 - 0.97 9.6 6.4 0.25 11.5 1.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FliC PF12445.8 EAX85664.1 - 2.2 8.6 6.8 17 5.7 0.2 3.2 3 0 0 3 3 3 0 Flagellin protein DAG_kinase_N PF14513.6 EAX85664.1 - 4.4 7.5 10.3 2.1 8.5 0.3 3.2 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Coilin_N PF15862.5 EAX85664.1 - 6.7 6.5 15.1 0.016 15.0 3.4 2.3 2 0 0 2 2 2 0 Coilin N-terminus GAGA_bind PF06217.12 EAX85664.1 - 9.9 6.3 10.8 0.24 11.7 3.8 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family RabGAP-TBC PF00566.18 EAX85665.1 - 1.2e-13 51.2 4.7 1.7e-13 50.8 4.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 EAX85667.1 - 4.1e-05 23.3 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MgtE_N PF03448.17 EAX85667.1 - 0.003 18.1 0.4 0.0086 16.7 0.4 1.9 1 1 0 1 1 1 1 MgtE intracellular N domain DivIC PF04977.15 EAX85668.1 - 0.0022 17.7 1.8 0.0022 17.7 1.8 6.8 2 1 4 7 7 7 1 Septum formation initiator Cep57_CLD_2 PF14197.6 EAX85668.1 - 0.0048 17.0 1.8 0.0048 17.0 1.8 5.2 5 2 0 5 5 5 1 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.7 EAX85668.1 - 0.065 13.5 0.3 0.065 13.5 0.3 3.8 5 0 0 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Baculo_PEP_C PF04513.12 EAX85668.1 - 0.74 9.9 33.5 0.3 11.1 7.4 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 EAX85668.1 - 1 8.9 67.5 0.69 9.4 24.6 3.1 1 1 1 2 2 2 0 Intermediate filament protein DUF4618 PF15397.6 EAX85668.1 - 1.2 8.4 61.3 3.4 7.0 6.8 4.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.19 EAX85668.1 - 2.4 6.0 49.3 5.1 4.9 49.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EAX85668.1 - 3.2 6.5 67.5 0.039 12.8 15.6 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 EAX85668.1 - 7.4 6.5 62.5 0.064 13.2 15.3 5.2 1 1 3 5 5 5 0 Bacteriophage Mu Gam like protein MtrB PF05440.12 EAX85668.1 - 8.8 6.8 7.7 17 5.9 0.3 3.7 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4108 PF13390.6 EAX85670.1 - 9.2e-62 207.2 4.9 1e-61 207.0 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85670.1 - 0.12 12.6 0.2 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GPS2_interact PF15784.5 EAX85673.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85673.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85674.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85674.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX85676.1 - 9.7e-157 519.6 13.9 1.2e-156 519.3 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85676.1 - 2.1 8.9 7.1 2.1 8.8 0.4 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX85677.1 - 2e-23 82.2 7.3 2e-23 82.2 7.3 5.8 4 2 2 6 6 4 2 Phage tail repeat like TMP PF05017.14 EAX85679.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85680.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX85681.1 - 5.8e-65 218.4 2.5 7.7e-65 218.0 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85681.1 - 0.094 13.1 0.7 0.11 12.8 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX85682.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX85683.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85683.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX85684.1 - 2.4e-30 104.4 36.0 3.9e-09 36.4 4.3 5.4 5 0 0 5 5 5 4 Phage tail repeat like YmaF PF12788.7 EAX85684.1 - 0.28 11.7 15.1 0.077 13.5 5.3 3.3 3 0 0 3 3 3 0 YmaF family PH_TFIIH PF08567.11 EAX85684.1 - 0.94 9.9 4.0 87 3.5 0.1 3.4 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain PA28_alpha PF02251.18 EAX85684.1 - 1.2 9.2 6.4 11 6.1 0.3 3.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit GUN4_N PF16416.5 EAX85684.1 - 2.4 8.2 7.6 8.5 6.5 0.3 3.8 2 1 1 3 3 3 0 ARM-like repeat domain, GUN4-N terminal RraB PF06877.11 EAX85684.1 - 3.2 8.5 7.3 77 4.1 0.1 3.6 2 1 1 3 3 3 0 Regulator of ribonuclease activity B DUF2797 PF10977.8 EAX85684.1 - 8.8 6.1 7.6 7.2 6.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2797) DUF3839 PF12943.7 EAX85685.1 - 1.8e-156 518.7 14.6 2.2e-156 518.4 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX85685.1 - 0.5 10.9 5.6 0.36 11.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85685.1 - 2.2 8.8 7.2 2.3 8.8 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX85686.1 - 1.9e-155 515.4 11.7 2.4e-155 515.0 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX85686.1 - 0.056 13.7 0.5 14 6.1 0.0 3.4 3 0 0 3 3 3 0 Tup N-terminal FKBP_N PF01346.18 EAX85686.1 - 0.16 13.0 1.2 0.34 11.9 0.3 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX85686.1 - 3.8 8.0 6.7 1.8 9.1 0.3 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85687.1 - 1e-40 138.1 0.4 2e-40 137.1 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX85687.1 - 0.017 15.7 0.2 0.069 13.8 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family IstB_IS21 PF01695.17 EAX85688.1 - 2.7e-06 27.3 0.4 0.036 13.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX85688.1 - 4e-05 23.9 0.1 0.00027 21.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX85688.1 - 0.00011 22.2 3.2 0.00021 21.3 3.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85688.1 - 0.00047 20.0 0.1 0.00083 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85688.1 - 0.0013 18.6 0.6 0.0033 17.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAX85688.1 - 0.0081 15.6 2.0 0.0081 15.6 2.0 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 EAX85688.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX85688.1 - 0.071 12.6 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX85688.1 - 0.079 13.4 0.1 0.54 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX85688.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX85688.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX85688.1 - 0.62 10.4 5.5 8.1 6.8 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1827) DDR PF08841.10 EAX85690.1 - 0.11 11.4 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain T5orf172 PF10544.9 EAX85692.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Trypan_PARP PF05887.11 EAX85693.1 - 0.047 13.7 10.2 0.074 13.0 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sulfatase PF00884.23 EAX85696.1 - 6.5e-13 48.7 0.1 1.7e-12 47.4 0.1 1.7 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EAX85696.1 - 0.017 13.7 0.0 0.14 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF1761 PF08570.10 EAX85696.1 - 0.078 13.2 4.6 0.14 12.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) DUF3839 PF12943.7 EAX85697.1 - 9.6e-155 513.1 13.8 1.2e-154 512.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX85697.1 - 0.029 14.4 0.1 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NTP_transf_6 PF06042.11 EAX85697.1 - 0.071 13.0 1.6 0.25 11.2 1.6 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Tup_N PF08581.10 EAX85697.1 - 0.22 11.9 2.4 15 6.0 0.0 3.3 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX85697.1 - 0.27 11.7 4.9 1.2 9.6 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85698.1 - 0.00086 19.1 0.9 0.0013 18.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain TMP PF05017.14 EAX85700.1 - 0.046 14.3 4.9 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85701.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_D5 PF03288.16 EAX85702.1 - 0.00015 22.2 2.2 0.00076 19.9 2.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX85702.1 - 0.043 12.9 1.0 0.06 12.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX85702.1 - 0.043 14.4 0.1 0.089 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX85702.1 - 0.084 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX85703.1 - 2e-57 193.2 4.3 2.2e-57 193.0 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX85705.1 - 5.6e-05 23.4 0.1 0.0003 21.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX85705.1 - 6.9e-05 22.9 3.0 0.00013 22.0 3.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85705.1 - 0.00033 20.5 0.0 0.0005 19.9 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85705.1 - 0.00096 19.0 1.2 0.0033 17.3 1.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85705.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX85705.1 - 0.041 13.3 0.1 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX85705.1 - 0.068 12.9 0.1 0.18 11.5 0.0 1.7 1 1 0 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX85705.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SWI2_SNF2 PF18766.1 EAX85705.1 - 0.079 12.6 0.7 0.12 12.0 0.3 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_25 PF13481.6 EAX85705.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX85705.1 - 0.15 12.3 4.3 4.9 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) TMEM43 PF07787.12 EAX85706.1 - 1.3e-47 162.3 0.5 1.8e-47 161.9 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 Colicin_E5 PF12106.8 EAX85706.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain ARA70 PF12489.8 EAX85707.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Amidase02_C PF12123.8 EAX85710.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pkinase PF00069.25 EAX85713.1 - 1.6e-72 244.1 0.0 1.9e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85713.1 - 4.6e-42 144.1 0.0 5.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85713.1 - 5.3e-09 35.8 0.0 3e-08 33.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX85713.1 - 0.0013 17.8 0.6 0.0022 17.0 0.6 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX85713.1 - 0.0094 15.3 0.3 0.015 14.7 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Shikimate_DH PF01488.20 EAX85713.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FTA2 PF13095.6 EAX85713.1 - 0.2 11.2 0.7 0.48 10.0 0.2 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3447 PF11929.8 EAX85714.1 - 2.2e-23 82.0 4.6 2.8e-23 81.7 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) 6PGD PF00393.19 EAX85715.1 - 4.9e-114 380.6 0.2 6.2e-114 380.3 0.2 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAX85715.1 - 1.7e-41 142.1 0.0 2.8e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAX85715.1 - 3.1e-06 27.7 0.1 8.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EAX85715.1 - 7.7e-06 26.0 0.1 4e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EAX85715.1 - 3.4e-05 23.8 0.0 7.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EAX85715.1 - 0.0002 21.4 1.4 0.00082 19.4 0.2 2.5 3 1 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EAX85715.1 - 0.0038 16.6 0.0 0.0088 15.4 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EAX85715.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.6 EAX85715.1 - 0.18 12.0 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IF4E PF01652.18 EAX85716.1 - 1.6e-27 96.2 1.3 1.9e-27 96.0 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Adeno_E3_CR2 PF02439.15 EAX85717.1 - 0.00018 21.2 0.6 0.00037 20.2 0.6 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EAX85717.1 - 0.0029 17.5 0.1 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.12 EAX85717.1 - 0.0056 16.5 0.6 0.0056 16.5 0.6 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF3827 PF12877.7 EAX85717.1 - 0.0067 14.9 0.4 0.014 13.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) Protocadherin PF08374.11 EAX85717.1 - 0.01 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 0 Protocadherin DUF4064 PF13273.6 EAX85717.1 - 0.011 16.0 0.3 0.011 16.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) 7TM_GPCR_Srv PF10323.9 EAX85717.1 - 0.039 13.3 0.1 0.064 12.6 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Rab5ip PF07019.12 EAX85717.1 - 0.15 12.7 0.8 0.33 11.6 0.8 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) K1 PF02960.14 EAX85717.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.8 3 1 1 4 4 4 0 K1 glycoprotein DUF4106 PF13388.6 EAX85718.1 - 4.7e-263 872.7 15.6 4.7e-263 872.7 15.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX85718.1 - 0.021 15.1 0.1 1 9.7 0.1 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated FapA PF03961.13 EAX85718.1 - 5.3 5.5 10.5 1.3 7.6 4.5 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4710 PF15828.5 EAX85721.1 - 0.09 12.9 0.0 0.098 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) AhpC-TSA PF00578.21 EAX85722.1 - 1.6e-38 131.4 0.0 2.3e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAX85722.1 - 4.4e-18 65.4 0.0 5.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAX85722.1 - 3.9e-12 45.8 0.1 6.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Gly_rich PF12810.7 EAX85723.1 - 7.3e-13 49.0 11.8 8.4e-13 48.8 11.8 1.0 1 0 0 1 1 1 1 Glycine rich protein KilA-N PF04383.13 EAX85724.1 - 1.7e-32 111.6 0.4 4.2e-32 110.3 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX85725.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85725.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85725.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85725.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85725.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85725.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85725.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85725.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85725.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85725.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85725.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85725.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) GGDEF PF00990.21 EAX85726.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX85726.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX85726.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF563 PF04577.14 EAX85727.1 - 6.8e-33 114.6 0.0 8.8e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ank_5 PF13857.6 EAX85728.1 - 1.1e-57 191.3 11.3 8.9e-12 45.0 0.1 6.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX85728.1 - 2.2e-52 173.3 9.5 5.3e-08 33.0 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_2 PF12796.7 EAX85728.1 - 1.5e-50 169.7 13.0 1.1e-15 58.0 0.5 6.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85728.1 - 3.7e-50 167.7 11.8 9.8e-10 38.8 0.1 9.4 2 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85728.1 - 2.1e-39 129.0 10.2 8e-06 25.8 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 EAX85728.1 - 6.1e-38 128.6 6.9 6.1e-38 128.6 6.9 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) ThiS-like PF14453.6 EAX85728.1 - 1.1e-06 28.6 7.7 8.6 6.5 0.1 7.4 2 1 5 7 7 7 1 ThiS-like ubiquitin PH_8 PF15409.6 EAX85728.1 - 0.00034 20.9 0.3 6.8 7.1 0.0 5.4 1 1 5 6 6 6 1 Pleckstrin homology domain CCG PF02754.16 EAX85728.1 - 0.01 16.0 0.1 6 7.1 0.0 2.7 1 1 1 2 2 2 0 Cysteine-rich domain TMIE PF16038.5 EAX85729.1 - 0.028 14.3 0.1 0.077 12.8 0.1 1.7 2 0 0 2 2 2 0 TMIE protein ARA70 PF12489.8 EAX85731.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Zincin_2 PF10103.9 EAX85732.1 - 0.25 10.6 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF4061 PF13270.6 EAX85734.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) HMG_box PF00505.19 EAX85735.1 - 2.3e-19 69.6 0.4 3.3e-19 69.1 0.2 1.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX85735.1 - 2.2e-10 41.0 0.5 3.2e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 HMG-box domain RR_TM4-6 PF06459.12 EAX85735.1 - 0.016 15.1 9.8 0.018 14.9 9.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 EAX85735.1 - 0.27 11.3 3.9 0.27 11.3 3.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S49_N PF08496.10 EAX85735.1 - 1.1 9.3 4.0 1.2 9.1 4.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 EAX85735.1 - 1.4 7.6 2.7 1.3 7.7 2.7 1.0 1 0 0 1 1 1 0 Presenilin Ribosomal_L27A PF00828.19 EAX85736.1 - 1.7e-21 77.2 0.0 2.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GPS2_interact PF15784.5 EAX85739.1 - 0.043 14.2 1.2 0.06 13.8 1.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX85740.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX85741.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85741.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDR PF08841.10 EAX85743.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain eIF3_subunit PF08597.10 EAX85745.1 - 2.4e-05 24.4 1.0 3.3e-05 23.9 1.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF1473 PF07341.11 EAX85745.1 - 0.00072 19.4 0.2 0.0013 18.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1473) DUF2634 PF10934.8 EAX85745.1 - 0.068 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Ank_5 PF13857.6 EAX85746.1 - 5.3e-13 48.9 0.9 4.3e-07 30.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX85746.1 - 4.9e-12 44.9 0.1 1.1e-05 25.4 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX85746.1 - 5.5e-10 39.7 0.2 6.4e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX85746.1 - 1.4e-09 38.3 0.3 1.6e-09 38.1 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX85746.1 - 2.9e-09 37.0 0.0 0.0022 18.4 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX85747.1 - 2.2e-29 101.4 0.6 3.8e-06 27.4 0.1 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX85747.1 - 4.1e-28 96.6 2.1 1e-06 28.9 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 EAX85747.1 - 8.4e-25 87.2 1.9 2.2e-13 50.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85747.1 - 1.2e-19 68.3 0.6 0.00012 22.2 0.0 5.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX85747.1 - 6.7e-18 64.5 0.1 1.6e-07 31.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) GPS2_interact PF15784.5 EAX85748.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85748.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85749.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85749.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAR1 PF03101.15 EAX85750.1 - 0.015 16.0 0.1 0.026 15.2 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain Transposase_mut PF00872.18 EAX85751.1 - 0.0035 16.3 0.7 0.0046 15.9 0.3 1.4 1 1 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX85751.1 - 0.028 14.4 0.3 0.041 13.9 0.3 1.3 1 0 0 1 1 1 0 Vta1 like DUF4770 PF15994.5 EAX85752.1 - 3.1 8.0 9.0 7.3 6.8 9.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4770) SIR2 PF02146.17 EAX85753.1 - 1.1e-49 168.7 0.0 1.5e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 EAX85753.1 - 0.0082 16.0 1.9 0.018 14.9 1.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EAX85753.1 - 0.16 11.9 3.8 0.98 9.3 0.2 2.7 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit zf-trcl PF13451.6 EAX85753.1 - 4.4 7.3 7.1 19 5.2 7.1 2.0 1 1 0 1 1 1 0 Probable zinc-ribbon domain Trypan_PARP PF05887.11 EAX85754.1 - 0.017 15.1 8.4 0.02 14.8 8.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85754.1 - 0.15 12.5 2.7 0.17 12.3 2.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX85755.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85755.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ashwin PF15323.6 EAX85757.1 - 0.34 10.9 14.7 0.55 10.2 14.7 1.2 1 0 0 1 1 1 0 Developmental protein DNA_repr_REX1B PF14966.6 EAX85759.1 - 0.0052 17.4 1.2 0.091 13.4 0.0 2.8 1 1 3 4 4 4 1 DNA repair REX1-B YojJ PF10372.9 EAX85759.1 - 0.013 15.6 0.1 0.21 11.7 0.0 2.8 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus LOH1CR12 PF10158.9 EAX85759.1 - 0.03 14.3 1.8 1.3 9.1 0.0 2.4 1 1 0 2 2 2 0 Tumour suppressor protein AAA_lid_10 PF17872.1 EAX85759.1 - 0.13 12.4 1.2 5.6 7.2 0.1 3.0 2 1 0 2 2 2 0 AAA lid domain MnmE_helical PF12631.7 EAX85759.1 - 0.18 11.9 6.3 4.2 7.5 0.3 2.3 1 1 1 2 2 2 0 MnmE helical domain Ribosomal_S20p PF01649.18 EAX85759.1 - 0.83 10.3 9.1 0.9 10.2 2.5 3.3 2 1 2 4 4 4 0 Ribosomal protein S20 GrpE PF01025.19 EAX85759.1 - 1.6 8.4 6.6 2.1 8.0 0.1 2.8 2 1 1 3 3 3 0 GrpE DUF3839 PF12943.7 EAX85761.1 - 6.8e-152 503.7 14.0 8.7e-152 503.4 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX85761.1 - 0.041 14.1 0.9 0.098 12.9 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX85761.1 - 1.3 9.5 5.0 2.2 8.8 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX85763.1 - 0.004 16.8 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX85764.1 - 2.6e-72 242.3 3.6 3.4e-72 241.9 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DDE_1 PF03184.19 EAX85766.1 - 3.5e-11 43.1 0.0 8.1e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-GRF PF06839.12 EAX85766.1 - 0.17 12.0 0.2 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 GRF zinc finger Peptidase_S8 PF00082.22 EAX85767.1 - 1.3e-05 24.6 4.2 0.00017 21.0 4.1 2.1 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAX85767.1 - 4e-05 23.6 0.0 0.00086 19.3 0.0 2.9 3 0 0 3 3 3 1 Proprotein convertase P-domain Fumble PF03630.14 EAX85768.1 - 2.2e-06 27.1 0.4 4e-05 22.9 0.4 2.2 1 1 0 1 1 1 1 Fumble Taeniidae_ag PF05596.11 EAX85768.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.5 2 0 0 2 2 2 0 Taeniidae antigen DUF3839 PF12943.7 EAX85770.1 - 4.9e-153 507.5 12.7 5.5e-153 507.3 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85770.1 - 0.099 12.5 0.9 0.37 10.6 0.9 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase DUF5398 PF17376.2 EAX85770.1 - 0.11 13.1 0.7 0.69 10.6 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) Rx_N PF18052.1 EAX85770.1 - 0.52 10.6 3.6 5.6 7.3 0.0 3.2 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX85770.1 - 3.8 8.0 7.1 2.5 8.6 0.6 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX85772.1 - 0.019 15.4 0.4 0.035 14.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX85772.1 - 0.38 10.8 3.4 6.8 6.8 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DDE_1 PF03184.19 EAX85773.1 - 2.5e-05 24.0 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PTR PF12789.7 EAX85775.1 - 1.2e-08 34.8 0.7 1.2e-08 34.8 0.7 3.6 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX85775.1 - 0.0056 16.3 0.7 0.0056 16.3 0.7 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX85775.1 - 5 7.6 10.1 12 6.4 0.7 3.7 3 0 0 3 3 3 0 Phage tail fibre repeat KilA-N PF04383.13 EAX85776.1 - 2.6e-17 62.7 0.1 5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain ComA PF02679.15 EAX85776.1 - 0.074 12.5 0.8 0.095 12.1 0.8 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF3839 PF12943.7 EAX85777.1 - 3.9e-127 422.7 6.9 4.4e-127 422.5 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85777.1 - 0.034 14.6 1.3 1.2 9.7 0.5 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Z1 PF10593.9 EAX85777.1 - 0.096 12.2 0.5 0.15 11.6 0.3 1.4 1 1 0 1 1 1 0 Z1 domain SMODS PF18144.1 EAX85778.1 - 0.036 14.2 0.1 0.055 13.6 0.1 1.2 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain GAS PF13851.6 EAX85779.1 - 2.1e-05 24.0 56.1 0.001 18.4 18.3 3.2 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding Latarcin PF10279.9 EAX85779.1 - 4.2e-05 23.9 4.5 0.19 12.1 0.0 4.1 1 1 1 2 2 1 1 Latarcin precursor Snapin_Pallidin PF14712.6 EAX85779.1 - 0.012 16.0 5.3 0.012 16.0 5.3 5.4 1 1 4 5 5 5 0 Snapin/Pallidin Fez1 PF06818.15 EAX85779.1 - 0.014 15.9 22.9 0.014 15.9 22.9 3.3 1 1 1 3 3 3 0 Fez1 Spc7 PF08317.11 EAX85779.1 - 0.018 13.9 63.4 0.02 13.8 21.2 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAX85779.1 - 0.019 14.3 40.8 0.13 11.6 14.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) THP2 PF09432.10 EAX85779.1 - 0.022 14.8 4.7 0.022 14.8 4.7 4.2 1 1 4 5 5 5 0 Tho complex subunit THP2 SHE3 PF17078.5 EAX85779.1 - 0.023 14.4 56.1 0.081 12.6 37.0 3.7 1 1 1 2 2 1 0 SWI5-dependent HO expression protein 3 FPP PF05911.11 EAX85779.1 - 0.029 12.6 57.8 0.035 12.3 57.8 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EAX85779.1 - 0.029 14.4 44.1 0.041 13.9 3.9 4.9 1 1 1 4 4 4 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EAX85779.1 - 0.034 14.5 39.9 1.5 9.2 1.1 6.1 3 2 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bacillus_HBL PF05791.11 EAX85779.1 - 0.039 13.8 46.2 0.096 12.5 5.0 3.6 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) SseC PF04888.12 EAX85779.1 - 0.053 13.1 0.5 0.053 13.1 0.5 4.8 1 1 3 5 5 5 0 Secretion system effector C (SseC) like family PI3K_P85_iSH2 PF16454.5 EAX85779.1 - 0.17 11.5 55.1 1.8 8.1 13.2 4.3 1 1 3 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF724 PF05266.14 EAX85779.1 - 0.17 11.7 51.8 0.82 9.5 6.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Spectrin PF00435.21 EAX85779.1 - 0.2 12.1 45.9 0.046 14.2 13.9 4.4 3 1 1 4 4 4 0 Spectrin repeat Laminin_II PF06009.12 EAX85779.1 - 0.25 11.3 52.1 0.023 14.7 12.8 4.0 2 2 0 3 3 3 0 Laminin Domain II HOOK PF05622.12 EAX85779.1 - 0.72 7.9 57.5 1.2 7.2 57.5 1.5 1 1 0 1 1 1 0 HOOK protein ATG16 PF08614.11 EAX85779.1 - 0.82 9.9 56.1 0.52 10.5 5.5 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EAX85779.1 - 1.3 9.6 60.3 0.85 10.2 13.8 4.2 3 1 2 5 5 4 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 EAX85779.1 - 2 9.2 37.6 0.25 12.1 5.9 5.2 1 1 2 5 5 5 0 Occludin homology domain Taxilin PF09728.9 EAX85779.1 - 2.6 7.1 61.1 2 7.5 23.5 3.5 2 1 2 4 4 4 0 Myosin-like coiled-coil protein ERM PF00769.19 EAX85779.1 - 3.4 7.4 56.6 5 6.9 35.9 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 EAX85779.1 - 5.3 7.2 56.9 0.87 9.8 11.0 4.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 EAX85779.1 - 7.2 6.7 37.3 2.2 8.4 2.1 3.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 FlgN PF05130.12 EAX85779.1 - 7.3 7.1 40.1 3.8 8.0 12.5 3.4 2 1 1 3 3 3 0 FlgN protein BAR_3 PF16746.5 EAX85779.1 - 7.6 6.2 44.9 0.082 12.6 12.2 3.6 1 1 1 3 3 3 0 BAR domain of APPL family HMMR_N PF15905.5 EAX85779.1 - 7.8 5.9 64.4 0.33 10.4 27.4 3.2 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 EAX85779.1 - 7.9 5.2 47.2 1.1 8.0 34.7 2.6 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like OmpH PF03938.14 EAX85779.1 - 8.4 6.7 59.6 3.4 8.0 15.5 4.8 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) ALIX_LYPXL_bnd PF13949.6 EAX85779.1 - 8.5 5.6 53.0 3.9 6.7 17.6 3.2 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Tropomyosin_1 PF12718.7 EAX85779.1 - 8.9 6.5 63.1 0.79 9.9 22.9 4.3 1 1 2 3 3 2 0 Tropomyosin like DUF3584 PF12128.8 EAX85779.1 - 9.2 3.6 53.5 0.47 7.9 36.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) NAD_Gly3P_dh_N PF01210.23 EAX85781.1 - 1.8e-38 132.0 0.0 2e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EAX85781.1 - 0.0021 18.6 0.0 0.037 14.6 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PAS PF00989.25 EAX85781.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 PAS fold Aa_trans PF01490.18 EAX85782.1 - 1.1e-06 27.7 15.5 1.3e-06 27.4 15.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRA-PH PF01503.17 EAX85783.1 - 0.12 12.8 3.5 8 7.0 4.2 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4108 PF13390.6 EAX85784.1 - 1.2e-50 171.1 5.8 1.3e-50 171.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85784.1 - 0.089 13.0 0.0 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide GGDEF PF00990.21 EAX85785.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX85785.1 - 0.37 11.1 13.6 0.53 10.6 13.6 1.4 1 1 0 1 1 1 0 PcfK-like protein Pox_A32 PF04665.12 EAX85786.1 - 3.9e-07 29.8 2.8 3.9e-07 29.8 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85786.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85786.1 - 6.3e-05 22.8 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85786.1 - 0.00016 21.7 3.4 0.00036 20.6 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85786.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85786.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85786.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85786.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85786.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85786.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85786.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85786.1 - 0.39 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX85787.1 - 2.3e-11 43.5 0.5 6.5e-11 42.1 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain FAM212 PF15342.6 EAX85789.1 - 0.015 15.1 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 FAM212 family YqzH PF14164.6 EAX85790.1 - 0.052 13.6 1.2 0.052 13.6 1.2 2.0 1 1 1 2 2 2 0 YqzH-like protein Proteasome PF00227.26 EAX85791.1 - 1e-37 129.5 0.0 1.2e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4174 PF13778.6 EAX85791.1 - 0.0071 16.8 0.1 2.1 8.8 0.1 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4174) TMP PF05017.14 EAX85792.1 - 0.059 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX85794.1 - 3.7e-08 33.3 1.3 3.7e-08 33.3 1.3 3.4 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX85794.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX85794.1 - 0.23 11.9 2.3 0.31 11.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) NPV_P10 PF05531.12 EAX85794.1 - 1.7 9.2 4.9 1.4 9.5 0.1 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein T5orf172 PF10544.9 EAX85795.1 - 9.2e-07 29.4 0.2 2.4e-06 28.0 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX85795.1 - 0.022 14.3 0.3 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAX85796.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85796.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85796.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX85796.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Gly-zipper_Omp PF13488.6 EAX85797.1 - 0.011 15.8 8.2 0.016 15.2 8.2 1.2 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX85797.1 - 0.72 10.2 5.4 0.49 10.7 3.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF4795 PF16043.5 EAX85798.1 - 0.059 13.0 9.2 0.35 10.4 1.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) EpuA PF11772.8 EAX85798.1 - 0.066 12.9 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta KilA-N PF04383.13 EAX85799.1 - 5.4e-40 135.7 0.1 1.4e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85799.1 - 0.006 16.7 0.3 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX85799.1 - 0.1 13.0 3.4 0.65 10.5 3.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX85800.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85800.1 - 2.9e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85800.1 - 5.2e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85800.1 - 0.00012 22.2 2.8 0.00028 20.9 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85800.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85800.1 - 0.0014 18.5 0.6 0.0031 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85800.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85800.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX85800.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX85800.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85800.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85800.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX85800.1 - 0.16 12.4 3.2 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX85800.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DNA_pol_B_2 PF03175.13 EAX85801.1 - 3.7e-25 88.7 7.3 1.9e-24 86.4 7.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX85802.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX85803.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX85804.1 - 0.014 15.4 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX85804.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DNA_pol_B_2 PF03175.13 EAX85805.1 - 7.4e-09 35.0 1.2 1.5e-08 33.9 1.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX85805.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX85805.1 - 0.16 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX85806.1 - 0.058 13.3 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Trypan_PARP PF05887.11 EAX85807.1 - 0.051 13.6 10.5 0.078 13.0 10.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85807.1 - 3.8 8.0 7.8 5.5 7.4 7.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX85808.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 EAX85809.1 - 1.2e-27 95.8 0.7 4.8e-15 55.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX85809.1 - 3e-17 62.6 0.2 6.7e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX85809.1 - 2.8e-05 24.1 0.2 0.34 10.9 0.0 3.1 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX85809.1 - 0.015 15.2 0.3 1.7 8.6 0.3 2.7 1 1 1 2 2 2 0 Myb DNA-binding like OTCace_N PF02729.21 EAX85810.1 - 2.7e-19 69.6 0.0 3.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EAX85811.1 - 7.3e-39 133.4 0.0 1.5e-38 132.3 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Alpha-amylase PF00128.24 EAX85812.1 - 2.1e-09 37.4 0.0 1.2e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain TPR_MLP1_2 PF07926.12 EAX85813.1 - 0.029 14.4 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX85813.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX85813.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family zf-RING_2 PF13639.6 EAX85814.1 - 0.00068 19.9 4.9 0.0014 18.9 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAX85814.1 - 0.0017 18.3 5.5 0.0033 17.4 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EAX85814.1 - 0.0027 17.4 1.2 0.0056 16.4 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EAX85814.1 - 0.0074 16.1 5.8 0.016 15.0 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EAX85814.1 - 0.015 15.3 8.0 0.04 14.0 6.5 2.3 2 0 0 2 2 2 0 Zinc-finger zf-RING_UBOX PF13445.6 EAX85814.1 - 0.079 13.0 5.5 0.19 11.8 5.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PRR20 PF15708.5 EAX85814.1 - 0.18 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 zf-rbx1 PF12678.7 EAX85814.1 - 0.3 11.4 3.5 0.67 10.3 3.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAX85814.1 - 0.39 10.6 4.8 1.5 8.8 4.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NPL PF17800.1 EAX85815.1 - 1.6e-08 35.1 0.0 1.8e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoplasmin-like domain C2 PF00168.30 EAX85816.1 - 8.7e-24 83.8 0.3 1e-23 83.6 0.3 1.0 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.9 EAX85816.1 - 0.042 13.6 0.8 0.08 12.7 0.3 1.6 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins PTR PF12789.7 EAX85817.1 - 3.9e-11 42.8 30.7 9.2e-08 32.0 5.3 4.9 5 0 0 5 5 5 3 Phage tail repeat like Collagen PF01391.18 EAX85817.1 - 1.7e-06 27.7 12.2 3.1e-06 26.9 12.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX85817.1 - 0.039 14.0 0.0 0.039 14.0 0.0 3.2 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 EAX85817.1 - 4 7.5 8.4 34 4.5 0.1 4.1 3 1 1 4 4 4 0 Laminin Domain II DUF4107 PF13389.6 EAX85819.1 - 9.8e-72 240.4 3.5 1.3e-71 240.0 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85820.1 - 2.5e-25 89.4 4.3 3.8e-25 88.8 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX85820.1 - 0.058 13.7 0.6 0.2 11.9 0.5 2.0 1 1 0 1 1 1 0 PRD domain DUF4108 PF13390.6 EAX85822.1 - 2.4e-61 205.8 8.9 2.7e-61 205.7 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) NPL PF17800.1 EAX85823.1 - 9.3e-05 22.9 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain Sec-ASP3 PF15432.6 EAX85823.1 - 0.047 13.8 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 AAA_7 PF12775.7 EAX85825.1 - 1.1e-07 31.5 0.3 2.3e-06 27.2 0.3 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EAX85825.1 - 0.00014 21.5 0.4 0.00031 20.5 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EAX85825.1 - 0.00024 21.1 0.2 0.0062 16.5 0.2 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EAX85825.1 - 0.0012 19.3 1.5 0.0099 16.3 0.6 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAX85825.1 - 0.0043 17.6 0.7 0.021 15.4 0.2 2.5 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 EAX85825.1 - 0.0077 16.0 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 EAX85825.1 - 0.043 12.9 0.1 0.086 11.9 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NICE-3 PF07406.11 EAX85825.1 - 0.044 13.8 2.5 0.051 13.6 0.4 2.2 2 0 0 2 2 2 0 NICE-3 protein RsgA_GTPase PF03193.16 EAX85825.1 - 0.064 13.2 1.2 0.26 11.2 0.1 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 EAX85825.1 - 0.065 13.8 2.9 10 6.7 0.1 3.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EAX85825.1 - 0.075 12.7 0.1 0.24 11.1 0.1 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EAX85825.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAX85825.1 - 0.34 11.3 1.1 3.7 7.9 0.5 2.8 2 1 1 3 3 3 0 AAA domain Peptidase_M4_C PF02868.15 EAX85825.1 - 1 9.2 4.3 7.2 6.4 0.7 3.0 3 0 0 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain DUF4108 PF13390.6 EAX85827.1 - 7.9e-65 217.1 6.2 8.8e-65 217.0 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85827.1 - 0.11 12.8 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pkinase PF00069.25 EAX85828.1 - 1.5e-51 175.3 0.0 2.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX85828.1 - 3.6e-33 114.9 0.0 4.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX85828.1 - 0.00012 21.5 0.0 0.00039 19.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like TMEM154 PF15102.6 EAX85829.1 - 0.0024 17.8 0.7 0.0027 17.6 0.7 1.2 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAX85829.1 - 0.0029 17.6 3.1 0.0042 17.1 3.1 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Protocadherin PF08374.11 EAX85829.1 - 0.0045 17.0 0.3 0.0057 16.7 0.3 1.2 1 0 0 1 1 1 1 Protocadherin Sigma_reg_N PF13800.6 EAX85829.1 - 0.007 16.6 0.9 0.0092 16.2 0.9 1.2 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DUF4064 PF13273.6 EAX85829.1 - 0.0078 16.5 0.4 0.0095 16.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF4083 PF13314.6 EAX85829.1 - 0.0095 15.9 0.6 0.016 15.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF5305 PF17231.2 EAX85829.1 - 0.01 15.3 0.7 0.015 14.7 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Shisa PF13908.6 EAX85829.1 - 0.01 16.1 0.3 0.011 16.1 0.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4330 PF14221.6 EAX85829.1 - 0.011 15.9 0.7 0.013 15.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF5455 PF17537.2 EAX85829.1 - 0.018 15.5 0.5 0.023 15.1 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Amnionless PF14828.6 EAX85829.1 - 0.018 13.9 0.0 0.021 13.7 0.0 1.0 1 0 0 1 1 1 0 Amnionless ODV-E18 PF10717.9 EAX85829.1 - 0.035 14.0 1.5 0.05 13.5 1.5 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Sarcoglycan_2 PF05510.13 EAX85829.1 - 0.057 12.2 0.2 0.066 12.0 0.2 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon MFS_3 PF05977.13 EAX85829.1 - 0.11 10.9 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3149 PF11346.8 EAX85829.1 - 0.5 10.0 4.2 0.84 9.3 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3149) MAAL_N PF05034.13 EAX85830.1 - 0.00024 20.8 0.4 2.2 7.9 0.0 3.5 1 1 3 4 4 4 2 Methylaspartate ammonia-lyase N-terminus Linker_histone PF00538.19 EAX85830.1 - 0.0056 17.0 3.9 0.21 12.0 0.5 3.0 1 1 1 2 2 2 1 linker histone H1 and H5 family SLH PF00395.20 EAX85830.1 - 0.1 12.6 5.2 43 4.2 0.1 4.6 1 1 4 5 5 5 0 S-layer homology domain SepRS_C PF18006.1 EAX85830.1 - 0.13 12.3 14.1 5.6 7.2 0.1 5.9 5 1 0 5 5 5 0 O-phosphoseryl-tRNA synthetase C-terminal domain UPF0126 PF03458.13 EAX85830.1 - 0.25 11.2 3.7 7.6 6.5 0.1 2.7 1 1 1 3 3 3 0 UPF0126 domain YdjC PF04794.12 EAX85830.1 - 0.28 11.1 2.1 12 5.8 0.1 3.3 2 2 2 4 4 4 0 YdjC-like protein Orthopox_C10L PF07020.11 EAX85830.1 - 3.3 8.5 23.0 30 5.4 4.7 4.1 1 1 1 2 2 2 0 Orthopoxvirus C10L protein Pax7 PF12360.8 EAX85830.1 - 5.1 7.4 8.2 31 4.9 0.0 4.1 3 1 1 4 4 4 0 Paired box protein 7 zf-C3Hc3H PF13891.6 EAX85832.1 - 1.7e-07 31.5 7.5 3.1e-07 30.7 7.5 1.4 1 0 0 1 1 1 1 Potential DNA-binding domain Aminotran_1_2 PF00155.21 EAX85835.1 - 1.2e-41 143.1 0.0 1.9e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EAX85835.1 - 0.021 13.5 0.0 0.039 12.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.21 EAX85835.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2407_C PF13373.6 EAX85836.1 - 1.6e-07 31.6 0.0 2.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EAX85836.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family PSP PF04046.16 EAX85837.1 - 0.051 13.4 0.3 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85838.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85839.1 - 0.038 14.4 0.8 0.079 13.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SEP PF08059.13 EAX85840.1 - 5.6e-09 36.5 0.0 1.8e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EAX85840.1 - 0.0022 18.2 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Spc29 PF17082.5 EAX85840.1 - 0.018 14.9 0.3 0.031 14.1 0.3 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 CLU_N PF15044.6 EAX85840.1 - 0.028 14.8 1.0 0.028 14.8 1.0 2.3 2 1 0 2 2 2 0 Mitochondrial function, CLU-N-term Armet PF10208.9 EAX85840.1 - 0.029 14.3 2.8 0.047 13.6 2.8 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Laminin_II PF06009.12 EAX85840.1 - 0.86 9.6 4.3 0.69 9.9 2.6 1.6 2 0 0 2 2 2 0 Laminin Domain II DSPc PF00782.20 EAX85841.1 - 1.4e-26 92.9 0.0 2.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAX85841.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sec61_beta PF03911.16 EAX85842.1 - 0.041 13.9 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Sec61beta family SpoIIP PF07454.11 EAX85843.1 - 0.052 13.0 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rota_NS35 PF02509.14 EAX85844.1 - 0.031 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 PSP PF04046.16 EAX85845.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85846.1 - 0.064 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX85847.1 - 3.1e-29 102.2 7.7 5.4e-29 101.4 7.7 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral JMY PF15871.5 EAX85847.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Formin_GBD_N PF18382.1 EAX85849.1 - 0.11 12.9 1.2 0.15 12.5 0.4 1.6 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain DUF2939 PF11159.8 EAX85850.1 - 0.018 15.5 0.4 0.026 14.9 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX85850.1 - 1.3 9.0 5.3 1.4 8.9 5.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX85851.1 - 0.039 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF5301 PF17225.3 EAX85851.1 - 0.17 12.4 3.3 0.14 12.6 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) Amidase02_C PF12123.8 EAX85852.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX85854.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX85855.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4108 PF13390.6 EAX85858.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly_rich PF12810.7 EAX85861.1 - 6.9e-33 114.6 34.3 8.2e-33 114.3 34.3 1.0 1 0 0 1 1 1 1 Glycine rich protein PaRep2a PF07903.11 EAX85862.1 - 0.019 14.8 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein TPR_MLP1_2 PF07926.12 EAX85862.1 - 0.038 14.1 0.2 0.047 13.8 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein T5orf172 PF10544.9 EAX85863.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85863.1 - 0.015 15.2 0.8 0.11 12.4 0.3 2.5 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX85863.1 - 0.14 11.6 0.9 0.31 10.5 0.3 1.7 2 0 0 2 2 2 0 Legume lectin domain DUF4108 PF13390.6 EAX85865.1 - 2.8e-55 186.2 6.5 3.1e-55 186.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85865.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Spo0A_C PF08769.11 EAX85867.1 - 0.072 13.2 0.3 0.16 12.1 0.2 1.5 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Amidase02_C PF12123.8 EAX85869.1 - 0.0045 16.7 0.1 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX85870.1 - 3.5e-51 173.6 0.7 4.9e-51 173.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85871.1 - 1.3e-157 522.5 12.8 1.7e-157 522.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85871.1 - 0.76 10.3 5.6 5 7.7 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX85871.1 - 1.2 9.4 4.1 3 8.2 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain PSP PF04046.16 EAX85873.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX85874.1 - 3.2e-141 468.8 11.9 3.9e-141 468.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85874.1 - 0.12 12.7 0.3 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85874.1 - 0.49 10.9 5.3 5.6 7.5 0.1 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX85875.1 - 2.4e-29 101.2 35.1 1.6e-20 72.9 9.3 5.9 3 3 3 6 6 6 3 Phage tail repeat like Poxvirus_B22R_C PF13168.6 EAX85875.1 - 0.017 14.6 0.1 0.043 13.3 0.1 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF480 PF04337.12 EAX85875.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF480 nsp9 PF08710.10 EAX85875.1 - 0.75 10.2 0.1 0.75 10.2 0.1 2.8 2 1 0 2 2 2 0 nsp9 replicase DUF4795 PF16043.5 EAX85875.1 - 2.2 7.9 21.5 0.14 11.7 1.4 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAX85877.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85878.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP FliJ PF02050.16 EAX85879.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX85880.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX85880.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3839 PF12943.7 EAX85881.1 - 5e-123 409.2 8.2 5.7e-123 409.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX85881.1 - 0.67 10.3 5.3 2.9 8.2 0.1 3.0 2 1 0 3 3 3 0 Rx N-terminal domain GPS2_interact PF15784.5 EAX85882.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX85882.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX85883.1 - 0.026 14.5 8.1 0.041 13.8 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX85883.1 - 1.6 9.2 5.1 2.3 8.7 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pox_A32 PF04665.12 EAX85884.1 - 2.1e-07 30.6 1.8 2.6e-07 30.4 1.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX85884.1 - 0.0047 16.6 0.1 0.0059 16.3 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX85884.1 - 0.049 13.1 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX85884.1 - 0.076 12.7 0.1 0.27 11.0 0.0 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX85884.1 - 0.099 12.9 4.5 5.4 7.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX85885.1 - 4.8e-32 110.1 0.4 1.1e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX85886.1 - 1e-157 522.8 14.8 1.3e-157 522.5 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85886.1 - 0.071 13.5 0.8 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function PRD PF00874.20 EAX85886.1 - 0.61 10.4 0.1 0.61 10.4 0.1 3.3 4 1 1 5 5 5 0 PRD domain KELK PF15796.5 EAX85886.1 - 1.3 9.6 6.1 3.4 8.2 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85887.1 - 1.1e-41 141.2 0.3 2.7e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX85887.1 - 0.004 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) T5orf172 PF10544.9 EAX85888.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX85889.1 - 1.1e-30 107.0 13.3 2.5e-30 105.8 13.3 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX85889.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4107 PF13389.6 EAX85890.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX85891.1 - 4.5e-150 497.8 11.2 5.6e-150 497.5 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX85891.1 - 0.27 11.6 1.6 0.43 10.9 0.2 2.2 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit APC_u14 PF16635.5 EAX85891.1 - 0.36 11.4 2.3 1 9.9 2.3 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr T5orf172 PF10544.9 EAX85892.1 - 5.8e-07 30.0 0.1 1.3e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX85892.1 - 0.045 13.6 1.7 0.098 12.5 0.7 2.2 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX85893.1 - 1.4e-145 483.1 9.6 1.8e-145 482.7 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX85893.1 - 0.2 12.1 1.7 5.9 7.4 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX85893.1 - 1.8 9.1 6.0 2.6 8.6 0.8 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4795 PF16043.5 EAX85894.1 - 0.014 15.0 22.8 0.17 11.4 2.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) RNA12 PF10443.9 EAX85894.1 - 0.56 8.9 8.9 0.49 9.1 2.5 2.1 2 0 0 2 2 2 0 RNA12 protein Phage_fiber PF03335.13 EAX85894.1 - 5.2 7.5 6.3 13 6.3 0.7 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Transposase_24 PF03004.14 EAX85894.1 - 5.4 7.1 13.0 6.2 6.9 3.4 3.5 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) Ank_4 PF13637.6 EAX85896.1 - 2.3e-07 31.2 0.1 2.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX85896.1 - 0.0006 20.2 0.2 0.1 13.1 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX85896.1 - 0.00061 20.0 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX85896.1 - 0.0037 17.8 0.1 0.0043 17.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85896.1 - 0.019 15.5 0.1 6.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat FlaF PF07309.11 EAX85896.1 - 0.019 14.9 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlaF UCH PF00443.29 EAX85897.1 - 3.1e-39 135.0 1.7 4.7e-39 134.4 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX85897.1 - 3.9e-11 43.1 0.7 1.7e-10 41.0 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAX85897.1 - 2e-06 27.3 0.3 4.8e-06 26.1 0.3 1.5 1 1 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Peptidase_C98 PF15499.6 EAX85897.1 - 0.00016 21.2 0.8 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase F_actin_cap_B PF01115.17 EAX85898.1 - 3.4e-74 249.5 0.0 3.8e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF4973 PF16343.5 EAX85898.1 - 0.092 12.8 0.1 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) Pox_VLTF3 PF04947.14 EAX85901.1 - 3.1e-05 23.7 4.9 3.1e-05 23.7 4.9 2.0 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like CdvA PF18822.1 EAX85901.1 - 0.025 14.4 3.2 0.043 13.6 1.0 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3189 PF11385.8 EAX85901.1 - 0.028 14.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) RecG_N PF17190.4 EAX85901.1 - 0.56 11.0 6.3 2.4 9.0 1.0 3.8 4 0 0 4 4 4 0 RecG N-terminal helical domain DUF2120 PF09893.9 EAX85901.1 - 0.75 9.9 5.0 0.36 10.9 1.9 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) ARA70 PF12489.8 EAX85902.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator PqiA PF04403.13 EAX85903.1 - 3.1e-14 53.1 20.1 4e-08 33.3 6.1 3.0 3 0 0 3 3 3 2 Paraquat-inducible protein A Caldesmon PF02029.15 EAX85903.1 - 0.016 14.0 8.0 0.024 13.4 8.0 1.2 1 0 0 1 1 1 0 Caldesmon Pox_A32 PF04665.12 EAX85905.1 - 7.3e-07 28.9 2.1 7.3e-07 28.9 2.1 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85905.1 - 4.8e-05 23.6 0.1 0.00032 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85905.1 - 0.00011 22.0 0.2 0.38 10.5 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85905.1 - 0.00025 21.1 3.4 0.00056 20.0 3.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85905.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX85905.1 - 0.0012 18.5 2.0 0.0068 16.1 0.1 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX85905.1 - 0.0018 18.1 0.8 0.0035 17.2 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85905.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX85905.1 - 0.091 12.8 0.6 1.3 9.0 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX85905.1 - 0.094 12.3 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX85905.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85905.1 - 0.5 10.6 3.8 10 6.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX85905.1 - 0.62 10.8 11.6 0.34 11.6 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 Ank_2 PF12796.7 EAX85906.1 - 0.00017 22.1 0.2 0.25 11.9 0.0 2.6 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX85906.1 - 0.00045 20.4 0.1 2.2 9.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAX85906.1 - 0.017 15.1 3.3 0.017 15.1 3.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX85906.1 - 0.033 14.8 0.1 5.2 7.8 0.0 3.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) PcfK PF14058.6 EAX85907.1 - 0.03 14.6 7.4 0.041 14.2 7.4 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX85907.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX85908.1 - 6.6e-07 29.0 2.7 6.6e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85908.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85908.1 - 4.3e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85908.1 - 0.00014 21.9 3.1 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85908.1 - 0.00053 19.8 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85908.1 - 0.0016 18.3 0.8 0.0032 17.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85908.1 - 0.002 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85908.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX85908.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85908.1 - 0.09 13.2 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85908.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85908.1 - 0.42 10.9 4.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX85909.1 - 9.5e-159 526.2 12.6 1.2e-158 525.9 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX85909.1 - 0.32 11.3 3.1 11 6.4 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX85909.1 - 3.9 8.0 7.7 2.6 8.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX85910.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85911.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85912.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX85913.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX85914.1 - 6.3e-155 513.7 13.7 8.2e-155 513.3 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX85914.1 - 0.054 13.8 0.4 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX85914.1 - 0.057 13.9 1.9 2 8.9 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX85914.1 - 0.53 10.9 3.4 0.56 10.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX85915.1 - 6.3e-73 244.3 3.6 8.2e-73 243.9 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX85917.1 - 1e-59 198.4 35.6 2.3e-34 117.2 15.3 5.0 3 2 1 5 5 5 2 Phage tail repeat like DUF3839 PF12943.7 EAX85919.1 - 9.4e-156 516.4 12.7 1.2e-155 516.1 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85919.1 - 0.088 13.2 1.7 0.37 11.2 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX85919.1 - 0.15 12.5 6.3 0.63 10.5 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85920.1 - 4.1e-34 116.8 0.4 9.1e-34 115.7 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Csm2_III-A PF03750.13 EAX85921.1 - 0.02 15.7 0.7 0.024 15.5 0.7 1.1 1 0 0 1 1 1 0 Csm2 Type III-A Spo12 PF05032.12 EAX85921.1 - 0.32 10.9 7.7 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4107 PF13389.6 EAX85924.1 - 1.1e-70 237.0 3.7 1.6e-70 236.4 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX85925.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX85927.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX85928.1 - 5.5e-30 104.7 2.2 6.1e-30 104.5 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX85928.1 - 0.078 13.4 0.1 0.14 12.5 0.1 1.5 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX85929.1 - 1.7e-146 486.1 12.6 2.3e-146 485.6 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX85929.1 - 0.013 14.8 0.0 0.067 12.4 0.0 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region PA28_beta PF02252.18 EAX85929.1 - 0.081 12.6 3.9 0.48 10.1 0.4 2.9 3 0 0 3 3 3 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX85929.1 - 2.9 8.4 6.2 2.6 8.6 1.2 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FOP_dimer PF09398.10 EAX85930.1 - 0.0025 18.0 0.2 0.011 16.0 0.0 1.9 1 1 0 2 2 2 1 FOP N terminal dimerisation domain LAGLIDADG_3 PF14528.6 EAX85930.1 - 0.007 16.7 0.5 0.05 13.9 0.1 2.0 2 0 0 2 2 2 1 LAGLIDADG-like domain HMD PF03201.16 EAX85930.1 - 0.017 15.4 0.1 0.049 13.8 0.0 1.7 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Latrotoxin_C PF15658.6 EAX85931.1 - 0.021 14.6 1.8 0.052 13.3 1.8 1.6 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Big_5 PF13205.6 EAX85931.1 - 0.14 12.9 2.5 0.77 10.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain Gly_rich PF12810.7 EAX85932.1 - 7.4e-20 71.9 33.3 8.9e-20 71.6 33.3 1.1 1 0 0 1 1 1 1 Glycine rich protein Methyltrn_RNA_3 PF02598.17 EAX85932.1 - 0.2 11.1 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase HEAT PF02985.22 EAX85933.1 - 1.9e-05 24.5 0.1 2.9 8.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EAX85933.1 - 5.4e-05 23.5 0.0 0.013 15.9 0.0 2.6 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EAX85933.1 - 0.0001 22.7 0.0 0.00071 20.0 0.0 2.4 3 0 0 3 3 3 1 HEAT-like repeat UME PF08064.13 EAX85933.1 - 0.016 15.1 9.2 4 7.4 0.1 5.3 4 1 1 5 5 5 0 UME (NUC010) domain DUF2678 PF10856.8 EAX85933.1 - 0.028 14.4 0.1 0.028 14.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) DNA_alkylation PF08713.11 EAX85933.1 - 0.092 12.4 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme RIX1 PF08167.12 EAX85933.1 - 0.12 12.2 8.7 0.09 12.5 0.3 3.8 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis TPR_7 PF13176.6 EAX85933.1 - 0.14 12.3 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1803 PF08820.10 EAX85933.1 - 0.18 11.8 4.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1803) NLRC4_HD PF17889.1 EAX85933.1 - 0.49 10.7 5.8 12 6.3 0.2 3.8 3 0 0 3 3 3 0 NLRC4 helical domain GGDEF PF00990.21 EAX85934.1 - 0.07 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain RGS12_us1 PF16613.5 EAX85934.1 - 0.44 10.9 6.3 0.75 10.1 6.3 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 Btz PF09405.10 EAX85934.1 - 1.2 9.4 10.4 2.4 8.4 10.4 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PcfK PF14058.6 EAX85934.1 - 2.1 8.6 16.4 3 8.1 16.4 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF4108 PF13390.6 EAX85935.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ribosomal_L33 PF00471.20 EAX85937.1 - 0.0073 16.7 5.7 0.066 13.7 0.1 2.9 2 0 0 2 2 2 2 Ribosomal protein L33 PP2C PF00481.21 EAX85938.1 - 3.1e-32 112.2 0.0 5.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EAX85938.1 - 2.2e-16 59.7 72.7 0.0052 17.2 3.4 13.2 7 4 9 16 16 16 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX85938.1 - 1.1e-12 47.5 63.1 0.0072 16.1 5.3 11.2 4 3 10 15 15 15 10 Leucine rich repeat PP2C_2 PF13672.6 EAX85938.1 - 1.7e-06 27.9 0.0 1.4e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3839 PF12943.7 EAX85939.1 - 2.7e-155 514.9 14.6 3.4e-155 514.6 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX85939.1 - 0.085 13.3 3.2 0.093 13.2 0.6 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX85939.1 - 0.19 12.3 5.5 0.3 11.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX85939.1 - 0.19 11.6 1.2 0.6 9.9 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX85939.1 - 0.2 12.1 7.7 5.7 7.5 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX85939.1 - 0.25 11.6 2.4 0.62 10.4 0.9 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit ZapB PF06005.12 EAX85939.1 - 0.93 10.0 4.5 0.58 10.6 0.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF4106 PF13388.6 EAX85940.1 - 9.4e-275 911.2 24.5 9.4e-275 911.2 24.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) PT PF04886.12 EAX85940.1 - 0.00017 21.0 44.5 0.00017 21.0 44.5 1.9 1 1 0 1 1 1 1 PT repeat KAR PF15222.6 EAX85940.1 - 0.0049 17.1 2.6 0.064 13.6 0.2 3.2 3 0 0 3 3 3 1 Kidney androgen-regulated DUF4108 PF13390.6 EAX85941.1 - 1.3e-58 197.0 5.1 1.5e-58 196.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX85941.1 - 0.096 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX85943.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85943.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85943.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85943.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85943.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85943.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85943.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85943.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX85943.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85943.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85943.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85943.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Gly-zipper_Omp PF13488.6 EAX85944.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX85944.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX85944.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX85944.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX85945.1 - 2e-71 238.6 13.3 2.2e-71 238.4 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAX85945.1 - 0.77 10.8 4.3 1.8 9.6 4.3 1.6 1 0 0 1 1 1 0 Deacetylase PdaC DUF4924 PF16271.5 EAX85946.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4924) Sugar_tr PF00083.24 EAX85947.1 - 1.7e-47 162.4 43.2 1.1e-24 87.1 15.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX85947.1 - 1.7e-25 89.7 37.9 4.2e-17 62.1 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX85947.1 - 1.9e-05 23.5 4.3 1.9e-05 23.5 4.3 3.7 1 1 0 3 3 3 1 MFS/sugar transport protein zf-C2HC5 PF06221.13 EAX85948.1 - 0.033 14.2 6.0 0.073 13.1 6.0 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 EAX85948.1 - 0.45 10.6 5.3 1 9.5 5.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EAX85948.1 - 0.78 9.2 5.6 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FYDLN_acid PF09538.10 EAX85948.1 - 1.3 9.7 2.7 1.8 9.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) PHD PF00628.29 EAX85949.1 - 4.5e-07 29.6 33.6 0.0002 21.2 12.6 3.2 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 EAX85949.1 - 1.7e-06 27.4 18.3 5.3e-05 22.7 2.1 2.6 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EAX85949.1 - 1.7 8.6 28.7 0.085 12.8 6.7 3.2 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Spo0A_C PF08769.11 EAX85952.1 - 0.087 12.9 0.3 0.18 11.9 0.3 1.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PSP PF04046.16 EAX85953.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85954.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX85955.1 - 2.1e-149 495.6 10.9 2.5e-149 495.3 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX85955.1 - 0.098 13.1 0.3 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX85955.1 - 0.99 9.9 5.6 4.4 7.8 0.4 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX85956.1 - 4.1e-25 87.8 0.4 1e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX85956.1 - 0.71 10.6 2.6 13 6.6 0.2 2.9 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX85957.1 - 3.2e-07 30.1 2.6 3.2e-07 30.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85957.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85957.1 - 6.5e-05 22.7 0.2 0.33 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85957.1 - 0.00019 21.5 3.5 0.00043 20.3 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85957.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX85957.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX85957.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX85957.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX85957.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX85957.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX85957.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX85957.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX85957.1 - 0.3 11.4 4.1 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PSP PF04046.16 EAX85958.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX85959.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX85960.1 - 0.078 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX85962.1 - 6e-156 517.0 14.1 7.5e-156 516.7 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85962.1 - 0.2 11.5 1.9 0.5 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX85962.1 - 0.24 11.7 2.5 1.6 9.1 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain DUF2408 PF10303.9 EAX85962.1 - 0.31 11.6 5.0 1.5 9.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX85962.1 - 0.94 10.0 8.5 2 8.9 1.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX85963.1 - 6.5e-07 29.1 3.1 6.5e-07 29.1 3.1 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85963.1 - 1.3e-05 25.5 0.2 9.8e-05 22.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX85963.1 - 0.00013 22.1 1.8 0.0003 20.8 1.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX85963.1 - 0.0004 20.2 0.1 0.00072 19.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX85963.1 - 0.0015 18.2 0.5 0.0081 15.8 0.5 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX85963.1 - 0.0015 18.3 0.2 0.38 10.5 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_11 PF13086.6 EAX85963.1 - 0.008 16.0 0.5 0.015 15.1 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX85963.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX85963.1 - 0.064 13.7 0.1 0.55 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX85963.1 - 0.067 12.7 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX85963.1 - 0.074 12.6 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX85963.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX85963.1 - 0.11 12.5 0.8 1.6 8.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX85963.1 - 0.69 10.1 8.6 6.8 6.9 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DNA_pol_B_2 PF03175.13 EAX85964.1 - 2.4e-10 39.9 2.1 1.3e-09 37.5 2.1 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX85965.1 - 3e-22 79.3 0.1 3.4e-22 79.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX85967.1 - 7e-71 237.6 1.6 9.2e-71 237.2 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Glyco_transf_64 PF09258.10 EAX85969.1 - 4.9e-08 32.6 1.6 2e-07 30.6 1.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Fez1 PF06818.15 EAX85970.1 - 0.022 15.2 0.2 0.027 14.9 0.2 1.0 1 0 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 EAX85970.1 - 0.03 14.4 0.3 0.13 12.4 0.0 2.1 2 1 1 3 3 3 0 bZIP transcription factor Uds1 PF15456.6 EAX85970.1 - 0.038 14.2 0.3 0.34 11.1 0.1 1.9 1 1 1 2 2 2 0 Up-regulated During Septation DUF641 PF04859.12 EAX85970.1 - 0.054 13.8 0.1 0.076 13.4 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TPT PF03151.16 EAX85971.1 - 1.2e-10 41.2 26.3 1.5e-10 41.0 26.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLATT_5 PF18160.1 EAX85971.1 - 0.031 13.6 0.3 0.031 13.6 0.3 2.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 LRR_1 PF00560.33 EAX85972.1 - 0.0078 16.6 0.8 63 4.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 EAX85972.1 - 0.017 15.5 7.6 7.9 7.1 0.1 5.2 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) SesA PF17107.5 EAX85972.1 - 0.069 13.3 2.1 0.84 9.8 0.8 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PIN_8 PF18476.1 EAX85972.1 - 0.37 10.6 8.8 0.041 13.7 3.4 2.0 2 0 0 2 2 2 0 PIN like domain LRR_8 PF13855.6 EAX85972.1 - 0.46 10.3 3.1 0.81 9.5 0.1 3.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 EAX85972.1 - 0.5 10.6 4.6 3.6 7.9 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Rop-like PF05082.13 EAX85973.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Rop-like Dynamin_N PF00350.23 EAX85975.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Dynamin family AA_permease_2 PF13520.6 EAX85976.1 - 0.00074 18.4 1.5 0.00087 18.2 1.5 1.1 1 0 0 1 1 1 1 Amino acid permease CBS PF00571.28 EAX85977.1 - 0.026 14.9 0.0 9.9 6.7 0.0 2.5 2 0 0 2 2 2 0 CBS domain DUF1349 PF07081.11 EAX85977.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) DUF3839 PF12943.7 EAX85978.1 - 1.3e-156 519.2 12.8 1.6e-156 518.9 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85978.1 - 0.12 12.3 0.9 0.32 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX85978.1 - 1.6 9.3 4.4 1.8 9.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) WASH-7_C PF14746.6 EAX85980.1 - 0.051 13.3 4.2 0.27 10.9 0.8 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Pox_Ag35 PF03286.14 EAX85980.1 - 0.59 9.9 5.1 0.94 9.2 5.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MCM6_C PF18263.1 EAX85980.1 - 5.1 7.4 8.8 1.2 9.4 5.1 1.8 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain PTR PF12789.7 EAX85981.1 - 4.3e-47 158.0 25.3 4.9e-31 106.6 11.4 4.7 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX85981.1 - 0.023 14.4 0.4 0.15 11.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX85981.1 - 0.072 13.3 0.7 0.31 11.3 0.0 2.4 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain DUF3839 PF12943.7 EAX85983.1 - 2.6e-153 508.4 13.3 3.3e-153 508.1 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX85983.1 - 0.25 11.2 2.7 0.61 9.9 0.4 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX85983.1 - 0.64 10.3 5.0 2.1 8.7 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain APC_u14 PF16635.5 EAX85983.1 - 0.67 10.5 3.2 0.92 10.1 1.4 2.1 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DUF2408 PF10303.9 EAX85983.1 - 1.2 9.7 5.3 0.92 10.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX85984.1 - 1.3e-06 28.0 2.3 1.3e-06 28.0 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX85984.1 - 3.9e-05 23.9 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX85984.1 - 4e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX85984.1 - 0.0011 19.0 3.5 0.0026 17.8 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX85984.1 - 0.002 17.8 0.4 0.014 15.1 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX85984.1 - 0.002 17.9 0.7 0.0062 16.4 0.6 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX85984.1 - 0.0044 16.8 0.0 0.0082 15.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX85984.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX85984.1 - 0.081 12.5 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX85984.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX85984.1 - 0.11 12.9 0.1 0.91 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX85984.1 - 0.21 12.0 3.0 0.74 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX85984.1 - 0.42 10.9 4.1 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX85988.1 - 2.4e-58 194.1 39.2 8.2e-32 109.1 14.3 4.6 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX85988.1 - 0.047 13.4 0.9 0.086 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX85989.1 - 1.4e-153 509.3 10.3 1.8e-153 509.0 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX85989.1 - 1.2 9.6 4.7 4.5 7.8 0.3 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX85991.1 - 1.6e-38 131.9 1.7 1.7e-38 131.8 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX85991.1 - 0.15 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein PmrD PF11183.8 EAX85994.1 - 0.041 14.0 0.2 0.16 12.1 0.0 2.1 2 1 1 3 3 3 0 Polymyxin resistance protein PmrD KAAG1 PF15354.6 EAX85998.1 - 8.5 7.0 10.3 0.63 10.6 1.2 2.9 1 1 2 3 3 3 0 Kidney-associated antigen 1 Beta_helix PF13229.6 EAX85999.1 - 0.046 13.6 23.3 0.016 15.1 15.9 2.4 1 1 1 2 2 2 0 Right handed beta helix region Oxidored_q5_N PF01059.17 EAX86000.1 - 0.032 14.3 0.6 0.078 13.1 0.6 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF4107 PF13389.6 EAX86001.1 - 5.1e-71 238.1 3.5 7.7e-71 237.5 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86001.1 - 0.02 15.2 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX86002.1 - 8.2e-13 48.2 36.4 1.9e-08 34.2 4.3 5.7 5 1 0 5 5 5 4 Phage tail repeat like EpuA PF11772.8 EAX86002.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PapD_N PF00345.20 EAX86003.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX86004.1 - 0.024 15.0 0.9 0.033 14.6 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX86004.1 - 2.1 7.3 3.8 2.3 7.2 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX86004.1 - 4.2 7.4 7.4 4.5 7.3 7.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX86005.1 - 0.025 14.6 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Pox_A32 PF04665.12 EAX86006.1 - 5.7e-07 29.3 2.4 5.7e-07 29.3 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86006.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86006.1 - 7e-05 22.6 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86006.1 - 0.00014 21.9 3.1 0.00033 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86006.1 - 0.00063 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86006.1 - 0.0013 18.6 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86006.1 - 0.0019 17.9 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86006.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX86006.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86006.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86006.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86006.1 - 0.4 10.9 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX86007.1 - 3.9e-33 113.6 0.4 9e-33 112.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86007.1 - 0.039 14.6 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family GPS2_interact PF15784.5 EAX86009.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86009.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Guanylate_cyc PF00211.20 EAX86010.1 - 1.5e-42 145.3 0.1 4.9e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX86010.1 - 3.8e-10 39.9 0.5 3.8e-10 39.9 0.5 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX86010.1 - 8e-05 22.6 0.1 0.00019 21.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold DUF4229 PF14012.6 EAX86010.1 - 0.0067 16.5 0.4 0.049 13.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4229) HNOBA PF07701.14 EAX86010.1 - 0.029 13.8 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Heme NO binding associated DUF202 PF02656.15 EAX86010.1 - 0.035 14.5 0.1 0.7 10.4 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PAS_4 PF08448.10 EAX86010.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold Vma12 PF11712.8 EAX86010.1 - 1.1 9.3 5.7 0.77 9.8 0.3 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4106 PF13388.6 EAX86011.1 - 3.7e-244 810.5 18.2 3.7e-244 810.5 18.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX86011.1 - 2.4e-06 27.2 0.5 6.4e-06 25.8 0.5 1.7 1 0 0 1 1 1 1 Poxvirus A32 protein KAR PF15222.6 EAX86011.1 - 0.11 12.8 2.0 1.8 8.9 0.1 3.0 3 0 0 3 3 3 0 Kidney androgen-regulated ArsC PF03960.15 EAX86011.1 - 2 8.5 4.1 1.8 8.6 0.1 3.1 4 0 0 4 4 4 0 ArsC family Gp_dh_C PF02800.20 EAX86014.1 - 2.8e-55 186.2 0.0 3.8e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAX86014.1 - 1.9e-28 98.8 0.1 5.4e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Hydrolase_like PF13242.6 EAX86014.1 - 0.018 15.1 0.1 0.8 9.8 0.0 2.6 3 0 0 3 3 3 0 HAD-hyrolase-like zf-CSL PF05207.13 EAX86014.1 - 0.058 13.1 0.2 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 CSL zinc finger CK_II_beta PF01214.18 EAX86015.1 - 7.7e-55 185.5 0.1 1e-54 185.1 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit GDA1_CD39 PF01150.17 EAX86016.1 - 1.1e-74 251.7 0.4 1.3e-74 251.4 0.4 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EAX86016.1 - 0.03 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Ank_4 PF13637.6 EAX86017.1 - 1.4e-15 57.5 0.5 1.1e-08 35.5 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX86017.1 - 9.8e-13 48.5 0.6 8.1e-10 39.2 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX86017.1 - 3.4e-12 45.4 0.7 2.6e-07 30.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX86017.1 - 1.2e-11 44.4 1.0 9.8e-08 32.1 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX86017.1 - 1.4e-11 44.4 0.1 1.7e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Stap_Strp_toxin PF01123.20 EAX86017.1 - 0.051 14.4 0.3 2 9.3 0.0 2.1 1 1 1 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain MetallophosN PF16371.5 EAX86017.1 - 0.16 12.3 0.0 4 7.8 0.0 2.0 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase PTR PF12789.7 EAX86018.1 - 1.1e-40 137.5 25.0 3.3e-34 116.7 13.8 4.3 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX86018.1 - 0.11 12.2 1.0 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX86019.1 - 0.043 14.3 0.6 0.091 13.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86020.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86021.1 - 0.07 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ribosomal_S3Ae PF01015.18 EAX86022.1 - 1.2e-56 191.5 3.3 1.5e-56 191.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DHR-2 PF06920.13 EAX86023.1 - 2.8e-12 46.1 6.4 4.9e-12 45.3 6.4 1.3 1 0 0 1 1 1 1 Dock homology region 2 PapD_N PF00345.20 EAX86024.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX86024.1 - 0.085 12.8 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX86025.1 - 0.014 15.8 0.7 0.016 15.6 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX86025.1 - 1.6 8.7 7.1 1.8 8.6 7.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDR PF08841.10 EAX86028.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain NIF PF03031.18 EAX86029.1 - 2.2e-45 154.2 0.0 2.7e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UCMA PF17085.5 EAX86032.1 - 0.089 12.8 0.1 0.089 12.8 0.1 2.3 3 0 0 3 3 3 0 Unique cartilage matrix associated protein TMEM154 PF15102.6 EAX86033.1 - 0.022 14.7 1.3 0.041 13.8 1.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 EAX86033.1 - 0.038 14.1 4.1 0.093 12.8 4.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Shisa PF13908.6 EAX86033.1 - 0.076 13.3 5.9 0.13 12.5 5.9 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.8 EAX86033.1 - 0.097 13.3 0.3 0.19 12.4 0.3 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMIE PF16038.5 EAX86033.1 - 0.67 9.8 5.3 1.6 8.6 5.3 1.6 1 0 0 1 1 1 0 TMIE protein DAG1 PF05454.11 EAX86033.1 - 1.2 8.5 6.1 0.43 9.9 2.8 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3827 PF12877.7 EAX86033.1 - 2.8 6.2 4.3 4 5.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 EAX86033.1 - 6.5 7.7 8.7 5.2 8.0 4.3 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Metallophos PF00149.28 EAX86034.1 - 5.9e-06 26.9 1.4 8e-06 26.5 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Erf4 PF10256.9 EAX86034.1 - 0.044 13.9 0.3 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family HEAT PF02985.22 EAX86035.1 - 0.091 13.1 0.0 1.7e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat TMEM154 PF15102.6 EAX86036.1 - 0.0053 16.7 0.1 0.0056 16.6 0.1 1.0 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAX86036.1 - 0.014 15.5 1.3 0.016 15.3 1.3 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PTP_tm PF18861.1 EAX86036.1 - 0.018 15.0 0.2 0.02 14.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 EAX86036.1 - 0.026 15.4 0.5 0.043 14.7 0.5 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 EAX86036.1 - 0.042 13.3 0.1 0.045 13.1 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Peptidase_M60 PF13402.6 EAX86037.1 - 9.2e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like F5_F8_type_C PF00754.25 EAX86037.1 - 0.0035 17.5 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX86039.1 - 0.0093 16.1 0.9 0.049 13.8 0.3 2.3 2 1 0 2 2 2 1 F5/8 type C domain MULE PF10551.9 EAX86040.1 - 2e-13 50.5 0.1 3.9e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX86040.1 - 0.084 12.6 1.1 0.14 11.8 1.1 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX86040.1 - 0.41 10.9 5.6 0.92 9.8 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX86040.1 - 0.46 10.2 5.2 0.71 9.6 5.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTR PF12789.7 EAX86041.1 - 2e-58 194.3 41.0 6.8e-33 112.5 19.8 5.1 4 2 2 6 6 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX86041.1 - 0.14 11.9 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX86041.1 - 0.52 10.7 5.4 6 7.3 0.2 3.8 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain DUF3839 PF12943.7 EAX86042.1 - 1.9e-77 260.0 10.6 2.5e-77 259.6 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86042.1 - 0.073 12.9 1.1 0.3 10.9 1.1 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase DUF4107 PF13389.6 EAX86043.1 - 2.6e-68 229.3 2.2 3.4e-68 228.9 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86043.1 - 0.12 12.7 0.5 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX86044.1 - 6.9e-88 294.2 8.6 8e-88 294.0 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX86044.1 - 0.02 14.4 0.3 0.022 14.2 0.3 1.1 1 0 0 1 1 1 0 Z1 domain TAF4 PF05236.14 EAX86045.1 - 0.58 9.9 7.8 1.4 8.6 7.8 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GED PF02212.18 EAX86046.1 - 0.047 13.8 0.2 0.18 12.0 0.2 2.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain Sen15 PF09631.10 EAX86046.1 - 0.047 14.0 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Sen15 protein RasGEF_N_2 PF14663.6 EAX86046.1 - 0.057 13.8 1.1 1.2 9.6 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 EAX86046.1 - 0.13 12.2 3.6 5.3 7.0 0.1 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) DUF3839 PF12943.7 EAX86047.1 - 1.3e-148 493.0 9.5 1.8e-148 492.6 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86047.1 - 0.011 16.2 0.3 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX86047.1 - 0.024 14.9 0.9 1.5 9.1 0.0 3.4 3 1 1 4 4 4 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX86047.1 - 0.058 13.2 0.8 0.19 11.6 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86047.1 - 1.1 9.8 3.9 3.4 8.2 0.2 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX86048.1 - 0.01 15.5 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86049.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Hydrolase_4 PF12146.8 EAX86051.1 - 3e-28 98.7 0.0 3.8e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX86051.1 - 4.2e-09 36.4 0.0 1.7e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAX86051.1 - 1.4e-05 25.8 0.0 1.6e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAX86051.1 - 5.1e-05 22.8 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EAX86051.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EAX86051.1 - 0.00034 19.6 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 EAX86051.1 - 0.0031 17.2 0.1 0.0073 16.1 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EAX86051.1 - 0.0046 16.8 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EAX86051.1 - 0.0074 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Say1_Mug180 PF10340.9 EAX86051.1 - 0.0097 14.8 0.5 0.033 13.1 0.1 2.1 1 1 1 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EAX86051.1 - 0.02 14.7 0.1 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EAX86051.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 EAX86051.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 EAX86051.1 - 0.087 12.6 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EAX86051.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase PapD_N PF00345.20 EAX86052.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX86053.1 - 0.016 15.6 0.3 0.019 15.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX86054.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta FliT PF05400.13 EAX86056.1 - 2.3 9.1 8.4 32 5.4 0.2 3.1 2 1 1 3 3 3 0 Flagellar protein FliT GDI PF00996.18 EAX86057.1 - 2.1e-165 550.5 0.0 2.3e-165 550.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor LRR_5 PF13306.6 EAX86058.1 - 1.6e-179 587.4 91.6 1.7e-29 102.4 6.4 8.8 1 1 4 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX86058.1 - 2.6e-60 200.1 1.5 0.0027 17.5 0.0 16.7 13 3 4 17 17 17 14 Leucine rich repeat LRR_4 PF12799.7 EAX86058.1 - 1.8e-18 66.3 18.1 0.32 11.5 0.5 15.2 14 2 2 16 16 16 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX86058.1 - 0.049 14.2 11.5 1e+02 4.1 0.1 9.0 8 1 0 8 8 8 0 Leucine Rich Repeat F5_F8_type_C PF00754.25 EAX86060.1 - 1.3e-06 28.5 1.0 3e-06 27.3 1.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Atg14 PF10186.9 EAX86060.1 - 0.0036 16.4 3.4 0.0052 15.9 3.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EAX86060.1 - 0.011 16.3 6.8 0.021 15.4 6.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region BRE1 PF08647.11 EAX86060.1 - 0.014 15.5 7.2 0.026 14.6 7.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1640 PF07798.11 EAX86060.1 - 0.017 15.2 3.7 0.031 14.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HTH_26 PF13443.6 EAX86060.1 - 0.023 15.1 0.3 0.35 11.3 0.4 2.9 2 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF4201 PF13870.6 EAX86060.1 - 0.042 13.6 8.7 0.08 12.7 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 EAX86060.1 - 0.19 12.1 3.3 0.35 11.2 3.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 EAX86060.1 - 0.2 11.4 14.2 1.8 8.4 5.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Wtap PF17098.5 EAX86060.1 - 0.29 11.1 6.5 0.49 10.3 6.5 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Geminin PF07412.12 EAX86060.1 - 0.52 10.0 16.7 1.4 8.6 4.1 2.4 1 1 1 2 2 2 0 Geminin DUF3450 PF11932.8 EAX86060.1 - 0.71 9.1 4.8 1.1 8.5 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 EAX86060.1 - 0.72 10.0 4.4 4.2 7.5 2.6 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 EAX86060.1 - 1.3 9.0 16.3 2.7 8.1 16.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF5339 PF17274.2 EAX86060.1 - 2.5 9.0 7.0 12 6.8 7.0 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5339) bZIP_1 PF00170.21 EAX86060.1 - 3.5 7.8 11.4 4.2 7.5 2.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 EAX86060.1 - 6.7 6.9 9.7 15 5.8 9.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ANAPC4 PF12896.7 EAX86061.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 hSH3 PF14603.6 EAX86061.1 - 0.23 11.9 2.9 0.87 10.1 0.1 2.6 3 0 0 3 3 3 0 Helically-extended SH3 domain PSP PF04046.16 EAX86062.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86063.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX86064.1 - 7.9e-148 490.4 11.5 1.1e-147 490.0 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX86064.1 - 0.0076 16.8 0.2 0.078 13.5 0.2 2.5 2 0 0 2 2 2 1 T5orf172 domain Fez1 PF06818.15 EAX86064.1 - 0.011 16.2 0.4 0.063 13.7 0.0 2.0 2 0 0 2 2 2 0 Fez1 ATP-synt_F6 PF05511.11 EAX86064.1 - 0.25 11.8 1.9 21 5.6 0.3 2.8 3 0 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 KELK PF15796.5 EAX86064.1 - 1.4 9.4 5.9 2.6 8.6 0.9 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Baculo_PEP_C PF04513.12 EAX86065.1 - 0.17 11.9 7.9 0.82 9.7 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 EAX86066.1 - 0.00015 22.2 13.9 0.00015 22.2 13.9 4.0 1 1 2 3 3 3 1 Zinc finger-containing protein QueC PF06508.13 EAX86066.1 - 0.12 11.9 2.6 0.41 10.1 2.6 1.9 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Baculo_PEP_N PF04512.12 EAX86066.1 - 0.53 10.6 5.7 0.8 10.0 0.3 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF4298 PF14131.6 EAX86066.1 - 3.2 7.8 30.6 3.1 7.8 0.5 6.2 3 2 3 6 6 6 0 Domain of unknown function (DUF4298) SHE3 PF17078.5 EAX86066.1 - 3.3 7.3 49.2 0.063 13.0 30.3 3.2 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Vac14_Fig4_bd PF11916.8 EAX86067.1 - 0.0024 17.6 0.2 0.0034 17.1 0.1 1.3 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding DUF3839 PF12943.7 EAX86068.1 - 2.2e-157 521.8 13.7 2.5e-157 521.5 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86068.1 - 4.5 7.8 9.2 1.4 9.4 0.7 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX86069.1 - 0.69 10.8 4.0 37 5.6 0.1 3.5 4 0 0 4 4 4 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX86070.1 - 0.0048 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX86070.1 - 0.25 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX86070.1 - 0.85 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Nuc_sug_transp PF04142.15 EAX86071.1 - 5.9e-08 32.2 8.6 5.9e-08 32.2 8.6 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 EAX86071.1 - 0.0018 17.6 10.6 0.0018 17.6 10.6 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EAX86071.1 - 0.0029 17.8 14.8 0.0029 17.8 14.8 3.4 3 2 0 3 3 3 2 EamA-like transporter family TMEMspv1-c74-12 PF11044.8 EAX86071.1 - 3.2 7.8 5.7 0.69 9.9 0.6 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4107 PF13389.6 EAX86072.1 - 1.5e-71 239.8 3.4 1.9e-71 239.4 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86072.1 - 0.076 13.4 0.7 0.14 12.5 0.1 1.7 2 1 0 2 2 2 0 ATPase inhibitor subunit zeta Pkinase PF00069.25 EAX86075.1 - 1.4e-50 172.1 0.0 1.7e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86075.1 - 4e-31 108.2 0.0 5.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX86075.1 - 0.12 11.7 0.0 1.4 8.1 0.0 2.3 2 1 0 2 2 2 0 Kinase-like DUF4108 PF13390.6 EAX86076.1 - 3.5e-62 208.6 8.3 3.8e-62 208.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX86076.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2897 PF11446.8 EAX86077.1 - 5.9 6.9 6.4 16 5.5 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1146 PF06612.11 EAX86078.1 - 0.045 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX86078.1 - 0.074 13.2 0.9 0.3 11.2 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) UBA PF00627.31 EAX86079.1 - 0.00099 19.0 0.4 0.13 12.2 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain WD40 PF00400.32 EAX86080.1 - 3.7e-07 30.7 9.1 0.00044 21.0 0.5 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat GAPES4 PF17157.4 EAX86080.1 - 0.0083 16.5 0.1 0.028 14.8 0.0 1.8 2 0 0 2 2 2 1 Gammaproteobacterial periplasmic sensor domain BBS1 PF14779.6 EAX86080.1 - 0.028 13.9 0.3 0.11 12.0 0.0 2.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 1 CASP_C PF08172.12 EAX86080.1 - 0.2 11.0 0.1 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 CASP C terminal ResIII PF04851.15 EAX86082.1 - 2.1e-05 24.6 0.7 3.2e-05 24.0 0.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86082.1 - 0.0003 20.6 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX86082.1 - 0.00039 20.7 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX86082.1 - 0.0019 18.1 0.0 0.0023 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX86082.1 - 0.007 16.7 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX86082.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 EAX86082.1 - 0.058 13.0 0.3 0.097 12.3 0.1 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EAX86082.1 - 0.07 12.9 0.0 0.097 12.4 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX86082.1 - 0.098 12.2 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX86082.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrmK PF04816.12 EAX86082.1 - 0.43 10.1 3.9 0.11 12.0 1.1 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase DUF2897 PF11446.8 EAX86083.1 - 0.15 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX86084.1 - 9e-60 200.8 7.2 1e-59 200.6 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX86085.1 - 7.6e-240 796.3 39.5 4.5e-239 793.7 32.0 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX86085.1 - 0.066 13.5 2.2 1.2 9.4 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated ArsC PF03960.15 EAX86085.1 - 0.36 10.9 2.6 0.62 10.1 0.1 2.7 3 0 0 3 3 3 0 ArsC family PSP PF04046.16 EAX86086.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX86087.1 - 1.9e-138 459.7 9.6 2.2e-138 459.5 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX86087.1 - 0.0091 15.7 1.0 0.03 14.0 0.2 2.2 2 1 0 2 2 2 1 Proteasome activator pa28 beta subunit DUF4107 PF13389.6 EAX86089.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86089.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase T5orf172 PF10544.9 EAX86090.1 - 6.5e-07 29.8 0.2 1.2e-06 28.9 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX86091.1 - 4e-85 285.1 6.5 4.8e-85 284.9 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX86091.1 - 0.023 14.2 0.4 0.026 14.0 0.4 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX86091.1 - 0.16 12.6 2.8 0.31 11.7 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX86092.1 - 3e-27 95.6 6.0 4.7e-27 95.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX86092.1 - 0.24 12.0 2.4 0.32 11.5 2.4 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr FYVE_2 PF02318.16 EAX86093.1 - 0.016 15.4 0.9 0.025 14.8 0.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Tetraspanin PF00335.20 EAX86094.1 - 1.1e-16 61.3 12.7 1.4e-16 61.0 12.7 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 EAX86094.1 - 0.011 15.8 7.8 0.05 13.6 1.7 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1772 PF08592.11 EAX86094.1 - 0.079 13.3 1.6 1.1 9.6 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4446 PF14584.6 EAX86094.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) HemY_N PF07219.13 EAX86094.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.8 2 1 1 3 3 3 0 HemY protein N-terminus CitMHS PF03600.16 EAX86094.1 - 0.25 10.5 3.6 0.48 9.6 3.6 1.5 1 1 0 1 1 1 0 Citrate transporter DUF2207 PF09972.9 EAX86094.1 - 0.27 9.9 9.2 2.3 6.9 6.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 EAX86094.1 - 0.93 8.2 15.0 0.22 10.3 8.6 1.9 2 0 0 2 2 2 0 Amino acid permease SUR7 PF06687.12 EAX86094.1 - 1.2 8.7 9.1 1.1 8.8 5.9 2.0 2 0 0 2 2 2 0 SUR7/PalI family DUF3899 PF13038.6 EAX86094.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) GPI2 PF06432.11 EAX86094.1 - 2 7.8 6.5 1.1 8.7 4.6 1.6 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase EssA PF10661.9 EAX86094.1 - 5.4 6.8 8.3 0.5 10.2 0.1 2.3 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA CooT PF10133.9 EAX86095.1 - 0.13 12.5 0.3 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT S1-P1_nuclease PF02265.16 EAX86096.1 - 5.4e-13 49.3 0.0 7.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease zf_CCCH_4 PF18345.1 EAX86096.1 - 0.25 11.5 1.3 0.45 10.6 1.3 1.5 1 0 0 1 1 1 0 Zinc finger domain S1-P1_nuclease PF02265.16 EAX86097.1 - 7.2e-12 45.7 0.0 7.7e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GPS2_interact PF15784.5 EAX86098.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86098.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86099.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86099.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ARA70 PF12489.8 EAX86100.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DDE_Tnp_4 PF13359.6 EAX86103.1 - 3.5e-31 108.0 0.0 7.5e-31 106.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX86103.1 - 9.1e-09 35.2 0.1 1.8e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAX86103.1 - 6.2e-08 32.5 0.1 2.5e-07 30.6 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain UCH_1 PF13423.6 EAX86103.1 - 0.00067 19.3 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Trypan_PARP PF05887.11 EAX86105.1 - 0.099 12.6 8.7 0.15 12.0 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86105.1 - 6.8 7.1 6.2 9.8 6.6 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX86106.1 - 3.6e-79 265.7 8.9 4.6e-79 265.3 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86106.1 - 0.057 14.0 0.3 0.096 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PSP PF04046.16 EAX86107.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86108.1 - 0.063 13.9 4.8 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86109.1 - 0.03 14.8 0.5 0.067 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX86110.1 - 9.2e-158 523.0 13.8 1.1e-157 522.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86110.1 - 0.18 12.4 5.6 0.47 11.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86110.1 - 0.42 11.1 7.1 2.1 8.8 1.0 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX86110.1 - 0.57 10.5 3.1 2.8 8.3 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain PSP PF04046.16 EAX86112.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86113.1 - 0.037 14.6 4.1 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat KilA-N PF04383.13 EAX86115.1 - 4.1e-13 49.1 0.0 5.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX86116.1 - 2.1e-152 505.4 15.0 2.6e-152 505.2 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86116.1 - 0.073 13.5 1.3 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX86116.1 - 0.15 12.4 5.7 0.4 11.0 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX86116.1 - 0.26 11.8 3.6 5.3 7.6 0.1 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX86116.1 - 0.28 11.0 1.8 0.73 9.7 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX86116.1 - 1.4 9.5 4.4 0.89 10.1 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 EAX86117.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX86117.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX86117.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3340 PF11818.8 EAX86118.1 - 0.015 15.5 0.7 0.021 15.0 0.7 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF3450 PF11932.8 EAX86121.1 - 0.0016 17.8 6.9 0.0016 17.8 6.9 3.7 1 1 4 5 5 5 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 EAX86121.1 - 0.013 15.7 18.4 0.013 15.7 18.4 4.4 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EAX86121.1 - 0.014 15.5 52.0 0.021 14.9 16.5 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 EAX86121.1 - 0.037 13.8 49.3 0.066 13.0 20.0 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CEP63 PF17045.5 EAX86121.1 - 0.29 11.0 47.7 0.48 10.3 47.7 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Sec34 PF04136.15 EAX86121.1 - 0.52 10.2 26.5 0.31 10.9 12.7 3.0 2 1 0 2 2 2 0 Sec34-like family TrmB PF01978.19 EAX86121.1 - 1.3 8.9 4.2 8 6.4 0.4 3.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB PSI_PsaF PF02507.15 EAX86121.1 - 1.4 8.8 3.9 1.5 8.6 1.3 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III MAD PF05557.13 EAX86121.1 - 4.9 5.4 57.5 1.1 7.6 2.0 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 EAX86121.1 - 6.7 7.1 19.5 1.6 9.1 9.9 2.8 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) ApoO PF09769.9 EAX86121.1 - 8.8 6.3 16.5 9.9 6.1 0.6 3.9 2 2 1 3 3 3 0 Apolipoprotein O DUF3839 PF12943.7 EAX86122.1 - 1.1e-148 493.3 13.4 1.4e-148 493.0 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86122.1 - 0.53 10.8 5.5 2.1 8.9 0.8 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX86122.1 - 1.8 8.9 4.1 6.9 7.0 0.0 3.3 2 2 1 4 4 4 0 Rx N-terminal domain Annexin PF00191.20 EAX86124.1 - 0.032 14.3 0.9 0.2 11.8 0.2 2.7 2 1 0 2 2 2 0 Annexin PRA-PH PF01503.17 EAX86124.1 - 2.9 8.4 5.6 3.2 8.3 3.5 2.0 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4106 PF13388.6 EAX86125.1 - 9.6e-271 898.0 17.5 9.6e-271 898.0 17.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) TMP PF05017.14 EAX86126.1 - 0.061 13.9 5.6 11 7.3 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86127.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX86129.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86129.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86130.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86130.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX86131.1 - 8e-37 127.2 16.3 2.4e-36 125.6 16.3 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX86131.1 - 0.14 12.1 0.1 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Ank_4 PF13637.6 EAX86132.1 - 3.2e-30 104.1 3.5 9.4e-14 51.6 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX86132.1 - 2.2e-27 95.5 9.9 1.5e-14 54.3 1.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX86132.1 - 3.3e-26 90.5 1.0 2.6e-07 30.8 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX86132.1 - 2.8e-25 88.0 8.7 7e-12 45.3 0.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86132.1 - 3.1e-19 67.0 1.5 8.8e-06 25.7 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat MetallophosN PF16371.5 EAX86132.1 - 1.4e-05 25.2 0.0 0.14 12.4 0.0 2.2 1 1 1 2 2 2 2 N terminal of Calcineurin-like phosphoesterase S4 PF01479.25 EAX86132.1 - 0.041 13.6 0.0 17 5.2 0.0 2.8 3 0 0 3 3 3 0 S4 domain NAD_binding_4 PF07993.12 EAX86132.1 - 0.047 12.9 0.5 0.7 9.0 0.5 2.1 1 1 0 1 1 1 0 Male sterility protein RNase_PH_C PF03725.15 EAX86132.1 - 0.075 13.1 0.0 6.5 6.9 0.0 2.7 1 1 2 3 3 3 0 3' exoribonuclease family, domain 2 Smr PF01713.21 EAX86132.1 - 0.13 12.7 0.3 1.6 9.1 0.1 2.4 1 1 1 2 2 2 0 Smr domain DUF3718 PF12514.8 EAX86132.1 - 0.92 9.7 3.3 20 5.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) MULE PF10551.9 EAX86133.1 - 1.5e-10 41.3 2.4 5.2e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX86133.1 - 0.0028 17.7 1.5 0.0087 16.1 1.5 1.8 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX86133.1 - 0.0048 15.8 0.3 0.0082 15.0 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family FliJ PF02050.16 EAX86134.1 - 0.022 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3839 PF12943.7 EAX86135.1 - 3.7e-157 521.0 14.3 4.8e-157 520.6 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86135.1 - 0.15 12.6 6.9 0.3 11.6 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX86135.1 - 0.16 12.4 2.4 0.41 11.1 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX86135.1 - 0.5 10.9 8.0 2.1 8.8 1.0 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86135.1 - 2.8 8.3 7.6 13 6.1 0.1 4.1 3 2 1 4 4 4 0 Tup N-terminal YnfE PF17452.2 EAX86136.1 - 0.021 15.1 0.2 0.021 15.1 0.2 2.3 3 0 0 3 3 3 0 Uncharacterized YnfE-like DUF5106 PF17127.4 EAX86136.1 - 0.024 14.9 0.4 0.14 12.4 0.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5106) YabA PF06156.13 EAX86137.1 - 0.045 14.4 3.4 0.15 12.7 3.4 1.9 1 0 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 EAX86137.1 - 0.41 11.1 3.5 0.88 10.0 3.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) LRR_5 PF13306.6 EAX86138.1 - 0.0026 17.7 3.6 0.0036 17.2 3.1 1.4 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) CARDB PF07705.11 EAX86138.1 - 0.026 14.8 0.6 0.051 13.8 0.6 1.5 1 0 0 1 1 1 0 CARDB GARS_N PF02844.15 EAX86138.1 - 0.1 13.4 0.0 0.14 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Collagen_bind_2 PF12904.7 EAX86139.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase GPS2_interact PF15784.5 EAX86140.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86140.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86141.1 - 0.041 13.9 9.9 0.066 13.2 9.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86141.1 - 6.3 7.3 6.0 9.5 6.7 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Kelch_6 PF13964.6 EAX86142.1 - 2.8e-17 62.3 9.5 5.4e-05 23.3 0.3 5.2 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EAX86142.1 - 2.1e-14 53.1 2.4 0.005 16.8 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EAX86142.1 - 5e-13 48.8 10.5 0.0059 16.6 0.0 5.5 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX86142.1 - 3.7e-12 45.6 4.4 0.00024 20.6 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EAX86142.1 - 1.4e-09 38.0 4.3 0.7 10.2 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EAX86142.1 - 5.3e-08 32.5 4.8 0.00017 21.4 0.1 4.9 6 0 0 6 6 6 2 Kelch motif DUF563 PF04577.14 EAX86143.1 - 6e-14 52.7 0.4 9.6e-14 52.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF4107 PF13389.6 EAX86145.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX86147.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Presenilin PF01080.17 EAX86148.1 - 8e-112 373.9 0.0 9.1e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Presenilin YL1 PF05764.13 EAX86148.1 - 0.076 13.1 9.1 0.12 12.5 9.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Podoplanin PF05808.11 EAX86148.1 - 0.8 9.8 2.4 0.51 10.4 0.3 1.7 2 0 0 2 2 2 0 Podoplanin FKBP_C PF00254.28 EAX86149.1 - 4.2e-15 55.8 0.0 7.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EAX86149.1 - 2.1e-05 24.3 4.2 1.5 9.2 0.3 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX86149.1 - 0.00094 19.6 1.2 0.012 16.2 0.4 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAX86149.1 - 0.0035 17.1 2.5 5.7 6.9 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAX86149.1 - 0.0056 16.5 0.0 8.4 6.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX86149.1 - 0.0059 16.9 0.4 11 6.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EAX86149.1 - 0.0073 16.4 0.3 0.07 13.2 0.0 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EAX86149.1 - 0.017 15.3 0.2 0.017 15.3 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX86149.1 - 0.13 13.2 0.1 19 6.4 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat Amidase02_C PF12123.8 EAX86150.1 - 0.0071 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86152.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX86154.1 - 2.8e-150 498.5 13.3 3.2e-150 498.3 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86154.1 - 0.059 13.2 0.6 0.23 11.3 0.1 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86154.1 - 0.26 11.8 8.5 1.6 9.3 1.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX86154.1 - 0.35 11.2 3.2 1.4 9.2 0.1 3.0 2 2 0 3 3 3 0 Rx N-terminal domain Trypan_PARP PF05887.11 EAX86155.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86155.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX86156.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain zf-C3H2C3 PF17122.5 EAX86158.1 - 6e-05 23.0 10.0 0.00012 22.0 10.0 1.6 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 EAX86158.1 - 0.0005 20.1 2.2 0.0012 18.8 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EAX86158.1 - 0.00072 19.5 9.8 0.0016 18.4 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EAX86158.1 - 0.0045 16.6 1.5 0.011 15.3 1.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EAX86158.1 - 0.014 15.7 10.4 0.014 15.7 10.4 2.3 2 0 0 2 2 2 0 Ring finger domain Cluap1 PF10234.9 EAX86158.1 - 0.041 13.3 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Clusterin-associated protein-1 BBS2_N PF14781.6 EAX86158.1 - 0.05 13.5 0.1 0.21 11.5 0.1 2.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Fer2_BFD PF04324.15 EAX86158.1 - 0.062 13.7 1.9 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain zf-rbx1 PF12678.7 EAX86158.1 - 0.1 12.9 10.1 0.33 11.3 10.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAX86158.1 - 0.12 12.2 6.7 0.33 10.8 6.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX86158.1 - 0.15 12.1 10.6 0.088 12.8 5.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger C1_1 PF00130.22 EAX86158.1 - 0.18 11.7 5.4 0.54 10.2 5.4 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EAX86158.1 - 0.2 12.0 7.4 0.047 14.0 3.4 2.0 2 0 0 2 2 1 0 C1 domain DZR PF12773.7 EAX86158.1 - 0.21 11.7 8.7 0.5 10.4 8.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EAX86158.1 - 0.31 11.2 7.4 0.086 13.0 3.6 2.2 2 0 0 2 2 1 0 Zinc ribbon domain zf-C3HC4_2 PF13923.6 EAX86158.1 - 0.43 10.5 11.3 1 9.3 11.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EAX86158.1 - 2 8.4 7.7 6.1 6.8 7.7 1.8 1 1 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 EAX86158.1 - 8.7 6.3 8.9 27 4.7 4.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cu_amine_oxidN1 PF07833.11 EAX86159.1 - 7.2 7.2 7.3 3.2 8.3 0.1 3.5 4 0 0 4 4 4 0 Copper amine oxidase N-terminal domain PTR PF12789.7 EAX86160.1 - 2.3e-23 82.0 14.6 2.2e-22 78.9 7.7 6.1 4 2 2 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX86160.1 - 3.1 7.3 19.5 1.4 8.4 0.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) HAD_2 PF13419.6 EAX86161.1 - 5.1e-24 85.3 0.1 6.4e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX86161.1 - 1.9e-12 47.9 0.0 5.7e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX86161.1 - 0.00028 20.9 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAX86161.1 - 0.033 14.6 0.0 0.053 13.9 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 EAX86162.1 - 9.2e-38 129.0 0.0 1.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAX86162.1 - 3.1e-14 52.9 0.0 4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAX86162.1 - 4.5e-09 36.0 0.1 7.4e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.25 EAX86163.1 - 3.2e-56 190.6 0.1 4e-56 190.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86163.1 - 3.5e-39 134.7 0.0 4.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX86163.1 - 7.8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX86163.1 - 0.0062 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF4116 PF13475.6 EAX86163.1 - 0.016 14.9 0.2 0.087 12.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Choline_kinase PF01633.20 EAX86163.1 - 0.038 13.6 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_MLP1_2 PF07926.12 EAX86164.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX86164.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX86164.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX86164.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family Armet PF10208.9 EAX86165.1 - 0.14 12.0 4.5 0.063 13.2 1.2 1.8 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding Chal_sti_synt_N PF00195.19 EAX86165.1 - 0.29 10.5 1.0 0.58 9.5 1.0 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX86166.1 - 4.7e-26 91.7 4.2 6.8e-26 91.2 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tubulin PF00091.25 EAX86167.1 - 2.2e-68 230.3 0.0 3.2e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX86167.1 - 2.4e-50 169.9 0.0 3.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAX86167.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAX86167.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Gly_rich PF12810.7 EAX86168.1 - 9.5e-21 74.8 25.3 1.1e-20 74.6 25.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Tubulin_C PF03953.17 EAX86169.1 - 3.1e-21 75.8 0.0 3.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin C-terminal domain PTR PF12789.7 EAX86170.1 - 7e-62 205.4 35.0 4.5e-34 116.3 14.2 4.1 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX86170.1 - 0.02 14.6 1.3 0.027 14.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX86170.1 - 4.2 8.1 6.9 13 6.5 0.2 3.3 2 1 3 5 5 5 0 Domain of unknown function (DUF4404) DUF1493 PF07377.12 EAX86171.1 - 0.021 15.3 0.6 0.045 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86172.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86173.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX86174.1 - 6.6e-102 340.1 6.6 7.5e-102 339.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX86174.1 - 0.028 13.9 0.2 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX86174.1 - 0.064 13.9 2.6 0.43 11.2 0.1 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5398) DUF4107 PF13389.6 EAX86175.1 - 5.5e-70 234.7 3.8 8.3e-70 234.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86175.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta SRP9-21 PF05486.12 EAX86177.1 - 0.25 11.8 9.0 14 6.2 0.0 2.8 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF4330 PF14221.6 EAX86177.1 - 1.9 8.7 4.6 8.2 6.6 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) FSAP_sig_propep PF03032.15 EAX86177.1 - 4 7.6 6.8 11 6.1 6.8 1.8 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide GPS2_interact PF15784.5 EAX86179.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86179.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX86181.1 - 1.6e-12 47.3 22.2 3.1e-09 36.7 3.9 5.1 5 0 0 5 5 5 3 Phage tail repeat like PatG_C PF18065.1 EAX86181.1 - 0.0075 16.2 0.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 PatG C-terminal FliD_C PF07195.12 EAX86181.1 - 0.014 14.9 3.6 0.78 9.1 0.9 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus EMP24_GP25L PF01105.24 EAX86181.1 - 0.087 12.8 4.1 2 8.3 1.1 3.3 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD TraW_N PF12477.8 EAX86182.1 - 5.1e-10 39.0 0.1 84 3.3 0.0 8.2 8 0 0 8 8 8 0 Sex factor F TraW protein N terminal CTD PF12815.7 EAX86182.1 - 1.4e-05 25.5 48.0 0.45 11.1 5.3 5.3 1 1 4 5 5 5 5 Spt5 C-terminal nonapeptide repeat binding Spt4 Keratin_B2_2 PF13885.6 EAX86182.1 - 5e-05 23.2 150.8 6.4 6.8 10.8 9.2 1 1 8 9 9 9 8 Keratin, high sulfur B2 protein DDR PF08841.10 EAX86184.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX86184.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3839 PF12943.7 EAX86186.1 - 6e-157 520.3 12.1 7.6e-157 520.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX86186.1 - 0.046 14.1 0.8 0.8 10.1 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86186.1 - 0.44 11.0 5.5 2.5 8.6 1.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86186.1 - 1 9.9 5.5 0.4 11.2 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX86187.1 - 1.2e-07 32.2 0.1 3e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX86187.1 - 0.0046 16.8 0.1 0.02 14.7 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX86187.1 - 0.12 11.9 0.3 0.52 9.8 0.1 1.8 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX86188.1 - 8.3e-32 109.4 0.7 1.6e-31 108.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Amidase02_C PF12123.8 EAX86190.1 - 0.0032 17.1 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86191.1 - 3e-72 242.1 3.6 3.9e-72 241.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF563 PF04577.14 EAX86193.1 - 8.2e-31 107.8 1.3 1.1e-30 107.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ChAPs PF09295.10 EAX86194.1 - 9.3e-06 24.9 0.6 0.00032 19.8 0.1 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TRAM_LAG1_CLN8 PF03798.16 EAX86195.1 - 8.2e-24 84.4 22.7 1.1e-23 84.1 22.7 1.2 1 0 0 1 1 1 1 TLC domain DUF4107 PF13389.6 EAX86196.1 - 4.9e-41 140.6 3.5 5.8e-41 140.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX86197.1 - 7.5e-268 888.5 23.4 7.5e-268 888.5 23.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX86197.1 - 0.11 12.9 2.4 1.6 9.1 0.1 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated DUF4107 PF13389.6 EAX86199.1 - 6e-72 241.1 3.0 7.8e-72 240.7 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Fumble PF03630.14 EAX86200.1 - 2.7e-45 155.0 0.1 7e-44 150.4 0.1 2.1 1 1 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 EAX86200.1 - 1.8e-06 27.7 0.0 2.2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 EAX86200.1 - 0.0045 16.7 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Peptidase_M8 PF01457.16 EAX86201.1 - 7e-08 31.6 0.0 1e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Leishmanolysin Nup35_RRM PF05172.13 EAX86202.1 - 0.072 13.1 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cuticle_1 PF08140.11 EAX86202.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Peptidase_M18 PF02127.15 EAX86204.1 - 3.2e-12 46.0 0.0 7.2e-12 44.8 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF952 PF06108.12 EAX86204.1 - 0.048 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Ank_2 PF12796.7 EAX86205.1 - 2.4e-179 582.4 26.5 5.7e-21 74.9 0.2 8.1 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86205.1 - 1.3e-112 366.4 8.0 9.9e-13 48.0 0.0 11.7 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 EAX86205.1 - 7.6e-93 301.2 0.0 4.4e-07 30.1 0.0 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 EAX86205.1 - 2.4e-91 299.0 0.0 2.1e-12 47.3 0.0 8.8 2 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86205.1 - 1.5e-75 240.1 0.0 6.5e-05 23.0 0.0 12.8 12 0 0 12 12 12 12 Ankyrin repeat FBD PF08387.10 EAX86205.1 - 0.00013 21.8 7.9 7.8 6.5 0.0 8.0 9 1 1 10 10 10 1 FBD DUF2795 PF11387.8 EAX86205.1 - 0.00037 20.6 7.6 2.2e+02 2.1 0.0 9.2 10 0 0 10 10 10 0 Protein of unknown function (DUF2795) DUF4988 PF16378.5 EAX86205.1 - 0.00039 20.1 0.3 39 3.8 0.0 5.5 1 1 5 7 7 7 0 Domain of unknown function Fer4_14 PF13394.6 EAX86205.1 - 0.0012 19.0 1.4 96 3.1 0.0 6.7 2 2 8 10 10 10 0 4Fe-4S single cluster domain BACK PF07707.15 EAX86205.1 - 0.051 13.7 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch Mago-bind PF09282.10 EAX86205.1 - 0.28 11.1 2.3 3.3e+02 1.3 0.0 5.1 8 0 0 8 8 8 0 Mago binding AGO_N PF18236.1 EAX86205.1 - 1.1 9.5 4.7 0.4 10.9 0.5 2.4 2 1 0 2 2 2 0 Argonaute N domain Metallophos PF00149.28 EAX86206.1 - 9.7e-25 88.3 0.3 1.1e-24 88.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX86206.1 - 0.0039 17.4 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EAX86206.1 - 0.0057 17.1 1.6 0.013 15.9 1.6 1.6 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF1493 PF07377.12 EAX86208.1 - 0.07 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX86209.1 - 7e-22 77.3 7.3 7e-22 77.3 7.3 6.0 5 2 1 6 6 6 2 Phage tail repeat like YmaF PF12788.7 EAX86209.1 - 0.0094 16.5 13.4 1.4 9.5 0.1 4.2 3 1 0 3 3 3 2 YmaF family DUF4116 PF13475.6 EAX86209.1 - 0.028 14.1 0.1 0.11 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX86210.1 - 8.5e-148 490.3 13.3 1.1e-147 490.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX86210.1 - 0.00082 19.9 0.8 0.0044 17.5 0.1 2.5 3 0 0 3 3 3 1 T5orf172 domain Rx_N PF18052.1 EAX86210.1 - 0.81 10.0 5.5 1.9 8.8 0.1 3.1 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX86210.1 - 0.89 10.0 3.7 6.8 7.2 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX86211.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Brr6_like_C_C PF10104.9 EAX86212.1 - 5.1e-19 68.4 5.5 5.1e-19 68.4 5.5 1.4 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain OAD_gamma PF04277.13 EAX86212.1 - 0.27 11.8 0.1 0.27 11.8 0.1 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Thoc2 PF11732.8 EAX86213.1 - 0.016 15.3 0.1 0.097 12.7 0.2 2.4 1 1 1 2 2 2 0 Transcription- and export-related complex subunit UNC45-central PF11701.8 EAX86213.1 - 1.2 9.1 8.8 4.9 7.1 0.3 4.0 1 1 2 3 3 3 0 Myosin-binding striated muscle assembly central Ank_2 PF12796.7 EAX86214.1 - 1.5e-96 317.1 58.1 9.1e-18 64.6 5.7 7.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86214.1 - 4.3e-95 311.0 22.0 8.2e-12 45.4 0.2 11.6 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 EAX86214.1 - 3.5e-86 280.2 19.0 2.1e-08 34.2 0.1 13.0 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 EAX86214.1 - 2.9e-72 230.0 11.4 2.3e-06 27.5 0.0 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 EAX86214.1 - 5.3e-64 211.4 44.5 2.7e-11 43.5 0.2 9.3 2 2 10 12 12 12 11 Ankyrin repeats (many copies) BCS1_N PF08740.11 EAX86214.1 - 0.13 12.2 0.2 8.2 6.4 0.0 2.8 2 1 0 3 3 3 0 BCS1 N terminal DUF3718 PF12514.8 EAX86214.1 - 0.48 10.6 13.9 11 6.3 0.1 6.6 5 3 3 8 8 8 0 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAX86215.1 - 4.8e-16 58.9 1.8 5.9e-09 36.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX86215.1 - 1.5e-11 44.7 0.5 1.7e-11 44.5 0.5 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX86215.1 - 8.2e-09 35.5 0.8 5.5e-06 26.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX86215.1 - 5.2e-07 29.8 0.5 2.9e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86215.1 - 4.7e-06 26.5 0.1 0.00054 20.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat RCC1 PF00415.18 EAX86216.1 - 6.9e-34 116.2 21.8 2.8e-09 37.4 0.0 8.0 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAX86216.1 - 6.9e-16 57.6 23.0 3.5e-06 26.7 0.4 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat CcmD PF04995.14 EAX86217.1 - 0.0061 16.6 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 EAX86217.1 - 0.0095 16.8 0.0 0.0095 16.8 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX86217.1 - 0.015 15.2 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 EAX86217.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NfeD PF01957.18 EAX86217.1 - 0.057 13.8 0.1 0.067 13.6 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF5385 PF17359.2 EAX86217.1 - 0.061 12.9 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Orf78 PF06024.12 EAX86217.1 - 0.065 13.5 0.2 0.093 13.0 0.2 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Phage_holin_2_1 PF04971.12 EAX86217.1 - 0.065 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF3149 PF11346.8 EAX86217.1 - 0.089 12.4 0.3 0.18 11.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3149) FeoB_associated PF12669.7 EAX86217.1 - 0.1 13.0 1.6 0.15 12.5 1.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4307 PF14155.6 EAX86217.1 - 0.2 11.5 2.0 0.3 10.9 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) AA_permease PF00324.21 EAX86219.1 - 4.3e-15 55.3 31.3 9.9e-15 54.1 31.3 1.5 1 1 0 1 1 1 1 Amino acid permease PTR PF12789.7 EAX86220.1 - 1.5e-26 92.2 14.7 4.4e-23 81.1 7.8 5.3 5 1 0 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX86220.1 - 0.091 12.5 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX86220.1 - 0.32 10.6 27.6 0.21 11.2 8.6 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF240 PF03086.14 EAX86220.1 - 0.65 9.9 5.2 2.9 7.8 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF3417 PF11897.8 EAX86220.1 - 0.67 10.4 0.0 0.67 10.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX86220.1 - 10 5.8 12.8 0.26 11.1 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PSP PF04046.16 EAX86221.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Chal_sti_synt_N PF00195.19 EAX86223.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain tRNA_synt_1c_R1 PF04558.15 EAX86224.1 - 0.0043 17.1 1.3 0.0072 16.3 0.1 1.8 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX86224.1 - 0.015 14.8 0.2 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX86224.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Gly-zipper_Omp PF13488.6 EAX86225.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX86225.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX86225.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX86225.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX86225.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PSP PF04046.16 EAX86226.1 - 0.071 13.0 0.9 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP OSTbeta PF15048.6 EAX86227.1 - 0.16 12.1 0.0 0.17 12.1 0.0 1.0 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Phosphorylase PF00343.20 EAX86229.1 - 1.2e-288 959.3 0.0 1.4e-288 959.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1348 PF07080.11 EAX86229.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Peptidase_M8 PF01457.16 EAX86230.1 - 8.2e-25 87.5 0.0 2.9e-24 85.6 0.0 1.8 2 1 0 2 2 2 1 Leishmanolysin ETRAMP PF09716.10 EAX86230.1 - 0.0003 20.8 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.6 EAX86231.1 - 7.2e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EAX86231.1 - 0.0014 18.9 0.5 0.0026 18.0 0.0 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EAX86231.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) ETRAMP PF09716.10 EAX86231.1 - 0.003 17.6 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) LRRC37AB_C PF14914.6 EAX86231.1 - 0.0041 17.0 0.1 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain DUF5305 PF17231.2 EAX86231.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4573 PF15140.6 EAX86231.1 - 0.035 13.9 7.3 0.058 13.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) LAP1C PF05609.12 EAX86231.1 - 0.038 13.1 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Syndecan PF01034.20 EAX86231.1 - 0.049 13.6 1.9 0.087 12.8 1.9 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3377 PF11857.8 EAX86231.1 - 0.057 13.4 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4366 PF14283.6 EAX86231.1 - 0.059 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5383 PF17355.2 EAX86231.1 - 0.099 13.0 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF2207 PF09972.9 EAX86231.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 EAX86231.1 - 0.14 12.5 12.8 6.2 7.2 12.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0258 PF06789.12 EAX86231.1 - 0.22 11.6 3.5 0.37 10.9 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Insulin_TMD PF17870.1 EAX86231.1 - 6.3 6.9 7.9 1.4 9.0 4.3 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Peptidase_M8 PF01457.16 EAX86232.1 - 5.7e-11 41.8 0.0 1.1e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 EAX86232.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Matrixin HMG_box PF00505.19 EAX86233.1 - 1.7e-09 38.0 0.5 5.8e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX86233.1 - 4.9e-05 23.8 0.0 8.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain Peptidase_M8 PF01457.16 EAX86234.1 - 8.7e-09 34.6 0.0 2.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Leishmanolysin TAS2R PF05296.13 EAX86234.1 - 0.084 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) DUF5305 PF17231.2 EAX86234.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 EAX86234.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF4106 PF13388.6 EAX86235.1 - 3e-226 751.5 24.9 3e-226 751.5 24.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX86235.1 - 0.15 12.4 3.9 1 9.7 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated PKcGMP_CC PF16808.5 EAX86236.1 - 0.0013 18.6 5.1 0.0013 18.6 5.1 18.2 17 4 4 21 21 21 8 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 EAX86236.1 - 0.0017 18.5 40.3 0.0017 18.5 40.3 10.4 1 1 11 12 12 12 3 Uncharacterised protein family (UPF0242) N-terminus Toxin_8 PF07365.12 EAX86236.1 - 0.14 12.4 0.7 35 4.7 0.0 3.9 2 0 0 2 2 2 0 Alpha conotoxin precursor GPS2_interact PF15784.5 EAX86238.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86238.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86239.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86239.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Exo_endo_phos PF03372.23 EAX86241.1 - 5.9e-12 45.6 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nucleo_P87 PF07267.11 EAX86241.1 - 3.2 6.5 22.4 4.3 6.1 22.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3839 PF12943.7 EAX86243.1 - 5.5e-157 520.4 14.4 6.8e-157 520.1 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86243.1 - 0.18 11.7 1.2 0.6 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86243.1 - 0.83 10.1 6.5 2.4 8.7 0.7 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX86244.1 - 2.3e-44 149.8 0.6 5e-44 148.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86244.1 - 0.011 16.4 0.1 0.043 14.4 0.0 2.0 2 0 0 2 2 2 0 Parathyroid hormone family DUF4106 PF13388.6 EAX86246.1 - 6.8e-244 809.6 17.1 6.8e-244 809.6 17.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX86246.1 - 0.01 16.1 0.1 0.63 10.4 0.2 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated ORC_WH_C PF18137.1 EAX86249.1 - 0.68 10.0 6.2 0.81 9.8 6.2 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Eapp_C PF10238.9 EAX86249.1 - 0.69 10.0 4.8 0.71 9.9 4.8 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein FoP_duplication PF13865.6 EAX86249.1 - 1.1 9.8 16.3 1.4 9.5 16.3 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PPL5 PF18168.1 EAX86249.1 - 1.3 8.2 5.2 1.3 8.2 5.2 1.0 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 EAX86249.1 - 3.2 6.4 9.3 3.9 6.2 9.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 EAX86249.1 - 4.1 7.2 13.1 5 6.9 13.1 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF2828 PF11443.8 EAX86249.1 - 5.3 5.0 7.5 5.7 4.9 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MAP17 PF15807.5 EAX86249.1 - 9 6.6 8.9 11 6.3 8.9 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DDE_1 PF03184.19 EAX86250.1 - 5.6e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GPS2_interact PF15784.5 EAX86252.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86252.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86253.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86253.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX86254.1 - 1.8e-155 515.5 12.3 2.2e-155 515.2 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX86254.1 - 0.72 10.5 3.1 0.79 10.4 0.1 2.7 3 1 1 4 4 4 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX86254.1 - 9 6.8 8.0 1.9 9.0 1.0 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX86257.1 - 2.7e-57 192.7 4.4 3e-57 192.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX86258.1 - 1.1e-05 25.8 3.2 6.9e-05 23.3 3.2 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX86258.1 - 0.0082 16.8 0.1 0.017 15.7 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX86258.1 - 0.011 15.6 0.1 0.028 14.4 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Meiosis_expr PF15163.6 EAX86259.1 - 0.021 15.5 1.0 0.03 15.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX86259.1 - 0.051 13.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX86259.1 - 8.5 6.4 13.7 0.14 12.0 2.8 3.2 4 1 0 4 4 4 0 Spo12 family Inhibitor_I69 PF13734.6 EAX86260.1 - 0.00076 19.9 0.2 0.0037 17.7 0.1 2.1 2 0 0 2 2 2 1 Spi protease inhibitor DUF2931 PF11153.8 EAX86260.1 - 0.0062 16.2 0.1 0.0078 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2931) DUF3839 PF12943.7 EAX86262.1 - 8.9e-134 444.4 7.8 1.1e-133 444.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86262.1 - 0.15 12.5 0.6 1.3 9.5 0.1 2.5 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX86263.1 - 3.1e-25 89.0 5.0 4.7e-25 88.5 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX86263.1 - 0.026 14.8 0.6 0.08 13.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain GPS2_interact PF15784.5 EAX86265.1 - 0.072 13.5 1.0 0.095 13.1 1.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX86266.1 - 0.18 11.7 9.4 0.28 11.2 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86266.1 - 8.1 6.9 6.2 12 6.4 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 EAX86267.1 - 8.2e-25 87.6 8.3 3.2e-24 85.7 8.3 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX86269.1 - 2.4e-12 46.7 39.1 3.1e-08 33.5 5.2 6.4 7 0 0 7 7 7 4 Phage tail repeat like Collagen PF01391.18 EAX86269.1 - 3e-05 23.7 10.3 5.2e-05 22.9 10.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX86269.1 - 0.021 14.9 5.4 0.043 13.9 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus LIFR_D2 PF17971.1 EAX86269.1 - 0.035 14.3 0.3 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain RecG_N PF17190.4 EAX86269.1 - 0.86 10.4 6.3 56 4.6 0.0 4.5 5 0 0 5 5 5 0 RecG N-terminal helical domain EMP24_GP25L PF01105.24 EAX86269.1 - 4.3 7.2 9.3 5.7 6.8 1.6 3.9 3 1 1 4 4 4 0 emp24/gp25L/p24 family/GOLD DUF4107 PF13389.6 EAX86271.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86271.1 - 0.077 13.4 0.5 0.15 12.4 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF667 PF05018.13 EAX86273.1 - 4.7e-83 277.5 0.2 5.2e-83 277.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF3781 PF12636.7 EAX86275.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX86276.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86276.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86277.1 - 0.14 12.1 11.5 0.15 12.0 11.5 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86277.1 - 0.69 10.4 4.9 0.77 10.2 4.9 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapD_N PF00345.20 EAX86278.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX86278.1 - 0.07 13.1 0.5 0.1 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Sec23_helical PF04815.15 EAX86279.1 - 0.15 11.9 0.3 0.31 10.9 0.3 1.6 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Annexin PF00191.20 EAX86279.1 - 0.16 12.1 0.3 0.61 10.2 0.2 2.0 1 1 1 2 2 2 0 Annexin UPF0242 PF06785.11 EAX86281.1 - 0.0004 20.5 11.3 0.0004 20.5 11.3 3.5 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EAX86281.1 - 0.00099 19.7 31.7 0.13 12.9 0.8 6.7 2 1 4 6 6 6 1 SlyX ATG16 PF08614.11 EAX86281.1 - 0.0013 19.0 5.2 0.0013 19.0 5.2 4.0 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EAX86281.1 - 0.0015 18.7 11.8 0.0015 18.7 11.8 3.9 1 1 2 4 4 4 2 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EAX86281.1 - 0.0016 18.0 45.7 0.0061 16.1 25.4 3.0 1 1 2 3 3 3 1 Golgin subfamily A member 5 HOOK PF05622.12 EAX86281.1 - 0.0038 15.5 37.2 0.051 11.7 37.2 2.1 1 1 0 1 1 1 1 HOOK protein DUF745 PF05335.13 EAX86281.1 - 0.01 15.6 27.2 0.014 15.1 14.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) TSC22 PF01166.18 EAX86281.1 - 0.02 15.2 2.1 0.02 15.2 2.1 5.7 4 2 3 7 7 7 0 TSC-22/dip/bun family NPV_P10 PF05531.12 EAX86281.1 - 0.026 15.0 13.6 0.57 10.7 0.1 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 EAX86281.1 - 0.029 14.6 44.8 0.055 13.7 7.9 4.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding ERM PF00769.19 EAX86281.1 - 0.08 12.7 40.2 0.072 12.9 11.7 2.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Csm1_N PF18504.1 EAX86281.1 - 0.29 11.5 42.4 0.39 11.1 1.3 6.6 5 1 2 7 7 6 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 EAX86281.1 - 0.35 10.8 12.3 0.66 9.9 0.2 5.1 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HALZ PF02183.18 EAX86281.1 - 0.35 11.1 15.3 0.19 12.0 2.2 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 EAX86281.1 - 0.38 10.9 46.6 0.14 12.3 4.6 4.2 1 1 2 3 3 2 0 Tropomyosin like TPR_MLP1_2 PF07926.12 EAX86281.1 - 0.64 10.1 49.4 2.1 8.4 1.3 4.8 1 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAX86281.1 - 0.71 9.9 49.9 0.088 12.8 18.0 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA1 PF07160.12 EAX86281.1 - 1 9.2 30.4 0.38 10.6 14.8 3.1 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DHR10 PF18595.1 EAX86281.1 - 1 9.4 43.1 0.076 13.1 10.1 3.9 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 EAX86281.1 - 1.1 9.7 50.1 4.9 7.7 16.7 3.7 2 2 1 3 3 3 0 Apg6 coiled-coil region SesA PF17107.5 EAX86281.1 - 1.3 9.2 16.9 0.028 14.6 6.3 3.0 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Fez1 PF06818.15 EAX86281.1 - 1.4 9.4 42.7 5.9 7.3 15.3 3.2 1 1 1 2 2 2 0 Fez1 CCDC144C PF14915.6 EAX86281.1 - 1.8 7.6 45.9 0.58 9.2 5.7 3.0 1 1 2 3 3 3 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 EAX86281.1 - 1.9 7.3 46.7 0.39 9.6 8.6 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Lebercilin PF15619.6 EAX86281.1 - 2.5 7.7 46.8 7.2 6.2 24.0 4.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 EAX86281.1 - 2.8 8.3 12.4 4 7.8 0.2 4.4 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 EAX86281.1 - 3.3 8.1 45.4 0.47 10.8 8.3 4.3 2 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 EAX86281.1 - 3.9 6.8 45.7 2.5 7.4 13.9 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding GrpE PF01025.19 EAX86281.1 - 4.8 6.8 38.7 2.3 7.9 1.9 4.7 1 1 2 3 3 2 0 GrpE Prefoldin_3 PF13758.6 EAX86281.1 - 4.9 7.3 21.3 2.5 8.2 6.2 3.9 2 2 2 4 4 4 0 Prefoldin subunit DUF724 PF05266.14 EAX86281.1 - 5.6 6.7 39.2 1 9.1 8.5 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 EAX86281.1 - 5.7 6.2 40.6 15 4.9 12.4 4.4 1 1 2 4 4 4 0 Tropomyosin FlaC_arch PF05377.11 EAX86281.1 - 7.1 7.1 33.3 4.7 7.7 3.6 6.2 3 1 4 7 7 7 0 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.19 EAX86281.1 - 7.6 4.2 43.7 25 2.5 43.7 1.7 1 1 0 1 1 1 0 Myosin tail ADIP PF11559.8 EAX86281.1 - 7.8 6.6 47.5 8.1 6.5 6.5 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 EAX86281.1 - 8.5 3.7 36.7 2.3 5.6 8.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.11 EAX86281.1 - 9.5 5.0 40.9 0.73 8.6 22.8 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3839 PF12943.7 EAX86282.1 - 5.3e-155 513.9 13.9 6.7e-155 513.6 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86282.1 - 0.019 15.4 2.0 0.086 13.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX86282.1 - 0.057 14.0 0.8 0.057 14.0 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX86282.1 - 0.084 12.4 0.0 0.24 10.9 0.0 1.8 1 1 0 1 1 1 0 SLOG cluster2 THOC7 PF05615.13 EAX86282.1 - 0.19 12.0 2.8 0.22 11.8 0.6 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 Glu-tRNAGln PF02686.15 EAX86282.1 - 1.2 9.5 3.5 1.4 9.2 0.5 2.6 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX86282.1 - 1.8 9.1 7.5 5 7.7 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX86283.1 - 8.5e-40 135.1 0.7 1.5e-39 134.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86283.1 - 0.01 16.4 0.3 0.045 14.4 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX86284.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX86284.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX86284.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX86284.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Ashwin PF15323.6 EAX86285.1 - 0.47 10.4 13.3 0.73 9.8 13.3 1.2 1 0 0 1 1 1 0 Developmental protein DUF3839 PF12943.7 EAX86286.1 - 4.3e-152 504.4 11.4 6e-152 503.9 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX86286.1 - 0.0066 17.0 0.3 0.077 13.5 0.2 2.7 3 0 0 3 3 3 1 T5orf172 domain Fez1 PF06818.15 EAX86286.1 - 0.039 14.4 0.7 0.14 12.6 0.1 1.9 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX86286.1 - 0.059 13.8 0.3 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86286.1 - 0.2 12.1 4.4 2.9 8.4 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX86287.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ras PF00071.22 EAX86289.1 - 2.6e-57 192.9 0.2 3.1e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86289.1 - 2.1e-33 115.1 0.1 3.6e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86289.1 - 5.8e-17 61.7 0.1 7.1e-17 61.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX86289.1 - 2.4e-05 24.0 0.4 0.00029 20.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX86289.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX86289.1 - 4.7e-05 22.9 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX86289.1 - 0.00022 21.2 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EAX86289.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain SRPRB PF09439.10 EAX86289.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX86289.1 - 0.021 15.2 0.0 0.028 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 EAX86289.1 - 0.022 14.0 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 EAX86289.1 - 0.028 14.7 0.0 0.085 13.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EAX86289.1 - 0.036 14.2 0.1 0.08 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX86289.1 - 0.037 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EAX86289.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Septin cobW PF02492.19 EAX86289.1 - 0.047 13.3 0.2 6.9 6.2 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EAX86289.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CheR PF01739.18 EAX86289.1 - 0.065 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain ATPase_2 PF01637.18 EAX86289.1 - 0.069 13.1 0.0 0.17 11.7 0.0 1.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EAX86289.1 - 0.085 12.4 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAX86289.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 NTPase Fez1 PF06818.15 EAX86290.1 - 0.001 19.5 34.8 0.001 19.5 34.8 2.9 1 1 1 2 2 2 1 Fez1 DUF3584 PF12128.8 EAX86290.1 - 0.0023 15.6 32.1 0.0023 15.6 32.1 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 EAX86290.1 - 0.02 13.8 60.3 0.084 11.7 27.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EAX86290.1 - 0.17 11.9 60.1 0.054 13.5 18.1 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EAX86290.1 - 0.94 9.7 55.2 0.37 11.0 19.4 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EAX86290.1 - 0.98 8.2 61.8 45 2.7 61.5 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) MscS_porin PF12795.7 EAX86290.1 - 1.2 8.7 56.1 1.4 8.4 9.6 3.2 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 EAX86290.1 - 1.4 7.8 52.0 1.8 7.4 20.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 EAX86290.1 - 1.5 9.1 23.6 1.7 8.9 6.5 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 EAX86290.1 - 1.7 8.4 41.2 3.5 7.3 26.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 EAX86290.1 - 1.8 8.6 38.9 0.042 13.9 8.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) T3SSipB PF16535.5 EAX86290.1 - 2.5 8.5 35.7 0.11 13.0 15.2 3.2 1 1 2 3 3 3 0 Type III cell invasion protein SipB MCPsignal PF00015.21 EAX86290.1 - 3.7 7.3 23.7 0.34 10.7 2.0 2.9 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PspA_IM30 PF04012.12 EAX86290.1 - 4.2 6.9 46.9 2.4 7.7 30.0 2.9 1 1 0 2 2 2 0 PspA/IM30 family APG6_N PF17675.1 EAX86290.1 - 5.4 7.5 62.6 21 5.7 22.5 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 EAX86290.1 - 7.3 6.6 63.8 0.75 9.9 44.0 2.9 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 EAX86290.1 - 7.7 6.7 40.8 0.092 12.8 7.4 4.4 2 2 1 3 3 3 0 TolA binding protein trimerisation ERM PF00769.19 EAX86290.1 - 7.8 6.2 57.7 0.048 13.5 40.0 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Herpes_gE PF02480.16 EAX86291.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PAP_PilO PF06864.12 EAX86291.1 - 0.059 12.2 0.1 0.091 11.6 0.1 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Peptidase_C25_C PF03785.14 EAX86291.1 - 0.57 10.1 3.7 0.37 10.7 0.2 2.4 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain TnpW PF14202.6 EAX86292.1 - 0.018 14.9 0.3 6 6.8 0.0 2.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpW EamA PF00892.20 EAX86295.1 - 6.4e-05 23.1 2.6 0.03 14.5 0.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 EAX86295.1 - 0.00044 19.8 0.5 0.0005 19.7 0.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 Jiraiya PF15038.6 EAX86295.1 - 0.0031 17.0 0.5 0.0055 16.2 0.1 1.7 2 0 0 2 2 2 1 Jiraiya PET117 PF15786.5 EAX86295.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF2614 PF11023.8 EAX86296.1 - 0.69 10.0 6.1 0.84 9.8 3.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain COX14 PF14880.6 EAX86296.1 - 8.4 6.3 7.3 2.3 8.1 4.2 1.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF5564 PF17719.1 EAX86298.1 - 0.24 11.6 14.4 45 4.3 0.1 5.6 1 1 5 6 6 6 0 Family of unknown function (DUF5564) CH PF00307.31 EAX86298.1 - 0.28 11.4 5.2 91 3.3 0.0 4.2 1 1 4 5 5 5 0 Calponin homology (CH) domain gp45-slide_C PF09116.10 EAX86298.1 - 3.4 7.8 21.3 28 4.8 0.1 5.8 1 1 4 6 6 6 0 gp45 sliding clamp, C terminal GSH-S_N PF02951.14 EAX86298.1 - 6.6 6.9 18.1 47 4.1 0.8 4.9 4 2 1 5 5 5 0 Prokaryotic glutathione synthetase, N-terminal domain MULE PF10551.9 EAX86299.1 - 1.6e-10 41.3 0.3 2.7e-10 40.5 0.3 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF948 PF06103.11 EAX86300.1 - 0.3 11.4 8.3 0.35 11.1 8.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NST1 PF13945.6 EAX86300.1 - 2.2 8.4 6.4 2.8 8.0 6.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3839 PF12943.7 EAX86301.1 - 3.7e-154 511.2 13.7 4.7e-154 510.8 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86301.1 - 0.22 11.4 2.0 0.56 10.1 0.6 2.2 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX86301.1 - 0.4 11.0 2.7 0.73 10.2 1.3 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX86301.1 - 0.62 10.6 6.0 4.7 7.8 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86301.1 - 1.9 9.1 5.9 0.83 10.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX86302.1 - 3.5e-156 517.8 12.2 4.4e-156 517.5 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX86302.1 - 0.51 10.7 3.3 0.39 11.0 0.2 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX86302.1 - 1 10.0 4.8 1.7 9.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86302.1 - 6.5 7.3 7.8 4 8.0 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX86303.1 - 3.5e-40 136.3 0.1 4.7e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain DUF4107 PF13389.6 EAX86305.1 - 3.3e-72 241.9 5.1 3.9e-72 241.7 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86305.1 - 0.066 11.6 1.0 0.088 11.2 1.0 1.1 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX86306.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX86307.1 - 2.2e-39 135.3 2.9 3.1e-39 134.9 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX86308.1 - 1.9e-41 140.4 1.3 3.1e-41 139.7 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Syntaxin PF00804.25 EAX86310.1 - 0.002 17.8 1.9 0.023 14.4 0.2 2.0 1 1 1 2 2 2 2 Syntaxin Importin_rep_6 PF18829.1 EAX86311.1 - 0.012 15.8 1.4 0.032 14.4 1.4 1.7 1 0 0 1 1 1 0 Importin repeat 6 zf-C3HC4_5 PF17121.5 EAX86311.1 - 0.23 11.4 1.2 0.75 9.7 1.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ARL2_Bind_BART PF11527.8 EAX86311.1 - 0.91 9.6 5.0 1.8 8.7 1.7 2.9 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART RRM_1 PF00076.22 EAX86313.1 - 3.6e-07 29.9 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EAX86314.1 - 4.4e-45 154.1 0.0 5.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86314.1 - 4.3e-16 59.0 0.0 8.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Repressor_Mnt PF11423.8 EAX86314.1 - 5.9 6.8 6.0 0.78 9.6 1.5 1.9 2 0 0 2 2 2 0 Regulatory protein Mnt Zip PF02535.22 EAX86315.1 - 0.12 11.6 2.4 0.15 11.2 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 EAX86315.1 - 0.22 9.9 2.8 0.27 9.6 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3043 PF11241.8 EAX86315.1 - 0.89 9.6 4.4 1.7 8.6 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CEP19 PF14933.6 EAX86315.1 - 2.6 8.3 13.8 2 8.7 12.0 2.0 1 1 0 1 1 1 0 CEP19-like protein Neur_chan_memb PF02932.16 EAX86315.1 - 4.2 7.4 7.2 6 6.9 7.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HSP70 PF00012.20 EAX86315.1 - 4.2 5.4 11.4 5.8 5.0 11.4 1.2 1 0 0 1 1 1 0 Hsp70 protein LRR_5 PF13306.6 EAX86316.1 - 1e-20 74.0 6.3 7e-15 55.1 2.7 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX86316.1 - 0.022 14.5 0.0 20 5.0 0.0 3.2 2 1 1 3 3 3 0 Leucine rich repeat MbeD_MobD PF04899.12 EAX86317.1 - 0.31 11.2 7.4 13 6.0 0.2 4.6 3 1 2 5 5 5 0 MbeD/MobD like NEMO PF11577.8 EAX86317.1 - 0.9 9.6 8.4 2.5 8.2 2.8 3.4 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO HrpB7 PF09486.10 EAX86317.1 - 1.3 9.4 3.6 5.9 7.3 0.8 2.8 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) KASH_CCD PF14662.6 EAX86317.1 - 2.6 7.8 46.2 4.8 7.0 14.5 3.0 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 EAX86317.1 - 2.6 8.7 19.4 3.2 8.5 0.3 5.0 4 1 1 5 5 5 0 SlyX HALZ PF02183.18 EAX86317.1 - 5.7 7.2 19.0 2.6 8.3 0.2 5.1 5 0 0 5 5 5 0 Homeobox associated leucine zipper WD40 PF00400.32 EAX86318.1 - 1.7e-08 34.9 1.7 1.1 10.2 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX86318.1 - 6.5e-07 29.6 0.7 0.021 15.1 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX86318.1 - 0.0024 17.8 0.3 0.31 10.9 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mcl1_mid PF12341.8 EAX86318.1 - 0.057 12.8 0.1 0.18 11.1 0.1 1.9 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Bromodomain PF00439.25 EAX86319.1 - 0.031 14.3 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Bromodomain Nairo_nucleo PF02477.15 EAX86319.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleocapsid N protein Ank_2 PF12796.7 EAX86320.1 - 2.1e-30 105.1 0.0 6.2e-16 58.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86320.1 - 7.6e-28 96.5 0.0 1.1e-12 48.2 0.0 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX86320.1 - 4.4e-27 93.3 0.0 2.6e-06 27.6 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX86320.1 - 1.3e-25 89.1 0.1 1.7e-07 31.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86320.1 - 5.3e-24 81.7 0.0 4.6e-05 23.5 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ribosomal_L30 PF00327.20 EAX86320.1 - 0.0047 16.8 0.1 1.7 8.6 0.0 3.7 4 0 0 4 4 4 1 Ribosomal protein L30p/L7e PSP PF04046.16 EAX86321.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86322.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86323.1 - 0.025 15.0 0.4 0.059 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX86323.1 - 0.26 11.4 2.3 18 5.5 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein NMT PF01233.19 EAX86325.1 - 6.6e-52 175.6 0.0 5.2e-51 172.6 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EAX86325.1 - 6.6e-31 107.5 0.1 1.1e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EAX86325.1 - 5.2e-06 26.7 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAX86325.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4094 PF13334.6 EAX86326.1 - 0.032 14.7 1.2 0.032 14.7 1.2 3.8 4 2 0 4 4 4 0 Domain of unknown function (DUF4094) ACP_PD PF04336.12 EAX86326.1 - 0.085 13.3 0.1 0.085 13.3 0.1 3.4 2 2 1 3 3 3 0 Acyl carrier protein phosphodiesterase DUF4407 PF14362.6 EAX86326.1 - 0.82 9.0 37.7 1.6 8.0 12.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 EAX86326.1 - 0.89 7.0 48.4 0.095 10.2 18.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DivIVA PF05103.13 EAX86326.1 - 4.8 7.3 51.6 0.29 11.2 15.2 4.3 3 1 1 4 4 4 0 DivIVA protein DEK_C PF08766.11 EAX86326.1 - 5.5 7.0 12.5 0.17 11.9 1.7 3.0 3 0 0 3 3 3 0 DEK C terminal domain Exonuc_VII_L PF02601.15 EAX86326.1 - 8.5 5.8 36.8 0.93 9.0 8.5 3.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF4107 PF13389.6 EAX86329.1 - 4.6e-66 222.0 12.9 2.2e-64 216.5 12.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) KilA-N PF04383.13 EAX86330.1 - 7.3e-23 80.6 0.1 1.5e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX86330.1 - 0.038 14.0 1.2 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin His_Phos_2 PF00328.22 EAX86330.1 - 0.33 10.3 3.6 0.5 9.6 3.1 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF3839 PF12943.7 EAX86331.1 - 1.2e-156 519.3 13.8 1.5e-156 519.0 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86331.1 - 0.11 12.9 1.7 0.36 11.3 0.3 2.0 2 0 0 2 2 2 0 Fez1 LD_cluster2 PF18163.1 EAX86331.1 - 0.12 11.9 0.1 0.46 10.0 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 Rx_N PF18052.1 EAX86331.1 - 0.48 10.7 2.7 3.1 8.1 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX86331.1 - 1.5 9.3 5.8 9.3 6.8 0.2 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86331.1 - 3.9 7.9 7.1 12 6.3 0.1 3.7 3 2 2 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX86332.1 - 3.4e-06 27.5 0.2 9.3e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX86332.1 - 0.045 13.6 0.2 0.15 12.0 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAX86333.1 - 5.6e-07 29.3 2.3 5.6e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86333.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86333.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86333.1 - 0.00012 22.2 2.8 0.00028 20.9 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86333.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86333.1 - 0.0012 18.7 0.5 0.0037 17.1 0.3 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86333.1 - 0.002 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86333.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX86333.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX86333.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86333.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86333.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86333.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Ank_2 PF12796.7 EAX86335.1 - 1.9e-25 89.2 0.0 1.2e-12 48.2 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86335.1 - 7.7e-22 77.4 0.0 2.4e-09 37.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86335.1 - 1.7e-17 61.7 0.0 0.00048 20.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EAX86335.1 - 4.6e-17 61.6 0.0 0.00061 20.1 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX86335.1 - 2.2e-16 59.7 0.0 7.8e-05 22.9 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Type_III_YscG PF09477.10 EAX86335.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) DUF1147 PF06615.11 EAX86335.1 - 0.13 12.3 0.1 48 4.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1147) Ins134_P3_kin PF05770.11 EAX86336.1 - 1.9e-21 76.5 0.1 1.1e-20 74.0 0.0 2.1 1 1 1 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 EAX86336.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain IstB_IS21_ATP PF08483.11 EAX86338.1 - 1.3e-08 34.6 1.3 4.6e+02 0.8 0.0 12.0 14 0 0 14 14 14 0 IstB-like ATP binding N-terminal BORG_CEP PF14957.6 EAX86338.1 - 1.7e-05 26.0 25.0 1.8e+04 -8.1 25.0 6.3 1 1 0 1 1 1 0 Cdc42 effector LDB19 PF13002.7 EAX86338.1 - 0.0023 17.7 5.3 76 2.9 0.0 4.9 1 1 9 10 10 10 0 Arrestin_N terminal like WW_FCH_linker PF16623.5 EAX86338.1 - 0.0027 18.4 44.3 99 3.8 0.3 12.2 1 1 11 13 13 13 0 Unstructured linker region between on GAS7 protein ResIII PF04851.15 EAX86339.1 - 2.6e-05 24.3 0.3 4.1e-05 23.6 0.3 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86339.1 - 0.0003 20.6 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX86339.1 - 0.00046 20.5 0.0 0.00067 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX86339.1 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX86339.1 - 0.0067 16.8 0.0 0.0091 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX86339.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX86339.1 - 0.081 12.5 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX86339.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2897 PF11446.8 EAX86340.1 - 1 9.3 4.2 2.2 8.3 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX86341.1 - 2.3e-57 192.9 4.2 2.5e-57 192.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX86342.1 - 1.5e-70 238.6 10.0 1.5e-70 238.6 10.0 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) Phage_fiber_2 PF03406.13 EAX86342.1 - 0.41 10.2 7.4 0.13 11.8 1.2 3.1 3 0 0 3 3 3 0 Phage tail fibre repeat ArsC PF03960.15 EAX86342.1 - 0.63 10.1 3.3 0.88 9.6 0.1 2.9 2 1 0 2 2 2 0 ArsC family RibD_C PF01872.17 EAX86344.1 - 1.1e-13 51.4 0.0 2.2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain Cupin_2 PF07883.11 EAX86344.1 - 1.7e-08 34.0 0.4 7.1e-08 32.1 0.2 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EAX86344.1 - 0.00085 18.9 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EAX86344.1 - 0.19 11.6 0.3 1 9.3 0.2 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Myb_DNA-binding PF00249.31 EAX86345.1 - 3.1e-13 49.7 0.7 8.7e-09 35.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86345.1 - 1.2e-10 41.5 2.2 6.7e-08 32.7 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX86345.1 - 0.0081 16.3 0.4 0.017 15.3 0.1 1.7 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX86345.1 - 0.012 15.8 0.2 6 7.1 0.0 2.8 1 1 1 2 2 2 0 Rap1 Myb domain CFAP91 PF14738.6 EAX86345.1 - 0.072 13.1 1.9 0.1 12.6 1.9 1.2 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 T5orf172 PF10544.9 EAX86346.1 - 1.5e-06 28.7 0.1 3.5e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX86346.1 - 0.043 13.3 0.5 1 8.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX86347.1 - 1e-156 519.6 12.0 1.2e-156 519.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86347.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86347.1 - 0.38 11.2 5.6 0.82 10.2 0.6 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX86348.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX86350.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86350.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86351.1 - 0.041 13.9 8.7 0.064 13.2 8.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) T5orf172 PF10544.9 EAX86352.1 - 0.00065 20.2 0.6 0.0018 18.8 0.2 1.9 2 0 0 2 2 2 1 T5orf172 domain DUF3839 PF12943.7 EAX86353.1 - 3.5e-152 504.7 10.7 4.5e-152 504.3 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86353.1 - 0.25 11.8 4.7 0.82 10.2 0.5 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX86354.1 - 5.1e-73 244.6 4.2 6.2e-73 244.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86354.1 - 0.12 10.8 0.9 0.17 10.2 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX86355.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX86357.1 - 1.3e-65 220.5 1.9 1.7e-65 220.1 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86357.1 - 0.082 13.3 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX86358.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase EF-hand_10 PF14788.6 EAX86359.1 - 0.0028 17.5 0.7 0.0075 16.1 0.1 2.0 2 0 0 2 2 2 1 EF hand EVC2_like PF12297.8 EAX86359.1 - 0.0046 15.7 0.1 0.0083 14.9 0.1 1.4 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein YABBY PF04690.13 EAX86359.1 - 0.012 16.2 0.5 0.024 15.2 0.5 1.4 1 0 0 1 1 1 0 YABBY protein DUF3839 PF12943.7 EAX86360.1 - 6.6e-156 516.9 16.0 8.4e-156 516.6 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86360.1 - 0.048 14.1 2.1 0.19 12.2 0.5 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX86360.1 - 0.22 11.3 2.2 0.47 10.3 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86360.1 - 0.76 10.3 7.8 2.2 8.8 0.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86360.1 - 4.8 7.6 7.4 13 6.2 0.1 3.8 3 2 2 5 5 5 0 Tup N-terminal TLD PF07534.16 EAX86361.1 - 1.7e-30 106.1 0.3 3.6e-30 105.0 0.1 1.7 2 0 0 2 2 2 1 TLD Zip PF02535.22 EAX86363.1 - 8.6e-07 28.5 13.5 4.1e-05 23.0 2.5 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter SPT_ssu-like PF11779.8 EAX86363.1 - 0.039 13.6 0.3 0.039 13.6 0.3 3.5 5 0 0 5 5 5 0 Small subunit of serine palmitoyltransferase-like DUF4220 PF13968.6 EAX86363.1 - 0.12 11.8 6.4 0.033 13.6 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) COE1_DBD PF16422.5 EAX86363.1 - 0.19 11.2 0.1 0.82 9.1 0.1 1.9 1 1 1 2 2 2 0 Transcription factor COE1 DNA-binding domain DUF4108 PF13390.6 EAX86365.1 - 6.2e-60 201.3 5.8 7e-60 201.1 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX86366.1 - 6.3e-120 399.1 11.5 7.9e-120 398.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86366.1 - 0.059 13.8 2.5 5.3 7.6 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX86368.1 - 4.4e-60 201.8 9.0 4.9e-60 201.6 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MCPVI PF02993.14 EAX86371.1 - 3.3 7.5 8.1 12 5.7 0.1 2.1 1 1 0 2 2 2 0 Minor capsid protein VI DUF2369 PF10179.9 EAX86372.1 - 0.029 14.8 0.3 0.23 11.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) BPA_C PF18040.1 EAX86372.1 - 0.28 11.1 4.7 1.2 9.1 0.1 3.6 4 0 0 4 4 4 0 beta porphyranase A C-terminal TagA PF12561.8 EAX86373.1 - 0.11 12.9 2.8 0.6 10.5 0.3 3.1 3 0 0 3 3 3 0 ToxR activated gene A lipoprotein domain Imm59 PF15597.6 EAX86373.1 - 5.8 7.5 9.0 11 6.6 0.1 3.9 4 0 0 4 4 4 0 Immunity protein 59 Dysbindin PF04440.16 EAX86374.1 - 0.011 15.8 1.2 0.022 14.9 1.2 1.4 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) BRCT_2 PF16589.5 EAX86374.1 - 0.037 14.4 0.1 0.76 10.2 0.0 2.9 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain zf-RING_2 PF13639.6 EAX86376.1 - 1e-09 38.6 8.3 1e-09 38.6 8.3 2.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX86376.1 - 3.8e-06 26.6 9.9 3.8e-06 26.6 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX86376.1 - 4.4e-05 23.2 9.9 4.4e-05 23.2 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAX86376.1 - 5.3e-05 23.1 10.5 5.3e-05 23.1 10.5 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 EAX86376.1 - 0.00023 21.4 9.2 0.00023 21.4 9.2 2.5 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAX86376.1 - 0.00039 20.2 8.0 0.00039 20.2 8.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX86376.1 - 0.00077 19.2 3.2 0.00077 19.2 3.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EAX86376.1 - 0.0011 18.9 1.7 0.0011 18.9 1.7 2.8 2 2 2 4 4 4 1 RING-type zinc-finger zf-RING_6 PF14835.6 EAX86376.1 - 0.0071 16.2 1.5 0.0071 16.2 1.5 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DZR PF12773.7 EAX86376.1 - 0.008 16.2 12.7 0.023 14.7 0.3 2.9 2 1 0 2 2 2 1 Double zinc ribbon Zn_ribbon_17 PF17120.5 EAX86376.1 - 0.0088 15.6 6.7 0.0088 15.6 6.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc-ribbons_6 PF07191.12 EAX86376.1 - 0.11 12.5 11.2 3.9 7.5 6.4 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_10 PF16685.5 EAX86376.1 - 0.26 11.4 8.6 0.61 10.3 8.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EAX86376.1 - 3.8 7.4 14.8 1.6 8.6 4.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_2 PF13240.6 EAX86376.1 - 5.3 6.9 14.8 1.5 8.7 0.5 4.3 4 1 0 4 4 4 0 zinc-ribbon domain zf-C3H2C3 PF17122.5 EAX86376.1 - 5.6 7.1 21.6 0.081 13.0 8.9 3.1 3 0 0 3 3 3 0 Zinc-finger Prok-RING_4 PF14447.6 EAX86376.1 - 5.9 6.8 18.3 6.6 6.7 9.8 3.1 2 2 2 4 4 4 0 Prokaryotic RING finger family 4 DUF4379 PF14311.6 EAX86376.1 - 6.8 7.1 16.3 6.7 7.2 5.8 3.1 2 1 0 2 2 2 0 Probable Zinc-ribbon domain Myb_DNA-binding PF00249.31 EAX86377.1 - 9.4e-25 86.6 0.6 1.1e-11 44.8 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86377.1 - 2.8e-22 78.7 1.8 7.8e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EAX86377.1 - 4.1e-05 23.9 1.5 0.00016 22.0 0.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Poxvirus_B22R_N PF13169.6 EAX86377.1 - 0.012 16.1 0.7 0.012 16.1 0.7 2.0 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal MADF_DNA_bdg PF10545.9 EAX86377.1 - 0.16 12.3 4.3 3.5 8.0 1.0 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4108 PF13390.6 EAX86379.1 - 3.2e-63 211.9 5.9 3.5e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GAGA_bind PF06217.12 EAX86380.1 - 0.086 13.1 5.8 0.094 13.0 5.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PcfK PF14058.6 EAX86380.1 - 3.4 8.0 16.9 4.7 7.5 16.9 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX86380.1 - 5.4 7.0 7.8 12 5.8 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX86381.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86381.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86381.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86381.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86381.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86381.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86381.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86381.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX86381.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86381.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86381.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86381.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX86382.1 - 1.5e-37 127.9 4.4 2.7e-37 127.1 1.3 2.5 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86382.1 - 0.014 16.0 0.3 0.053 14.1 0.0 2.1 2 0 0 2 2 2 0 Parathyroid hormone family Arrestin_N PF00339.29 EAX86385.1 - 1.3e-08 35.0 0.6 1.9e-07 31.2 0.6 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 EAX86385.1 - 3.3e-06 26.3 0.4 5.5e-06 25.6 0.4 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 EAX86385.1 - 0.00016 22.2 5.2 0.00023 21.6 0.2 2.7 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF563 PF04577.14 EAX86386.1 - 9.9e-12 45.4 0.0 1.1e-11 45.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5488 PF17590.2 EAX86386.1 - 0.046 13.5 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5488) HSP70 PF00012.20 EAX86387.1 - 1.1e-84 284.8 7.2 4.6e-72 243.1 0.5 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAX86387.1 - 3e-15 55.9 1.4 4.7e-15 55.2 0.4 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EAX86387.1 - 0.0027 17.0 0.0 0.0084 15.4 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase PilM_2 PF11104.8 EAX86387.1 - 0.024 13.7 0.3 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Actin PF00022.19 EAX86387.1 - 0.072 11.7 0.0 2 7.0 0.0 2.5 2 1 0 2 2 2 0 Actin StbA PF06406.11 EAX86387.1 - 0.082 12.1 1.6 0.14 11.4 0.0 2.3 3 0 0 3 3 3 0 StbA protein RPN1_C PF18051.1 EAX86388.1 - 1.5e-21 76.1 0.0 2.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EAX86388.1 - 8.3e-07 29.1 1.2 1.9e-06 28.0 0.2 2.3 2 0 0 2 2 2 1 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EAX86388.1 - 0.0031 17.9 0.1 0.017 15.5 0.0 2.3 2 1 1 3 3 3 1 HEAT repeats Amidase02_C PF12123.8 EAX86389.1 - 0.0024 17.5 0.0 0.0074 16.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX86389.1 - 0.22 11.4 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF3839 PF12943.7 EAX86390.1 - 3.4e-155 514.6 13.9 4.4e-155 514.2 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86390.1 - 0.22 12.0 3.4 2.1 8.8 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX86391.1 - 0.00017 22.1 0.5 0.00036 21.0 0.5 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX86391.1 - 0.009 15.9 0.2 0.049 13.5 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX86391.1 - 0.011 15.3 1.0 0.12 11.9 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain Gly_rich PF12810.7 EAX86392.1 - 1.4e-10 41.5 17.7 1.6e-10 41.3 17.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX86393.1 - 9.4e-15 55.2 18.0 1.1e-14 55.0 18.0 1.0 1 0 0 1 1 1 1 Glycine rich protein PSP PF04046.16 EAX86394.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86395.1 - 0.097 13.3 2.9 21 6.4 0.2 2.9 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX86396.1 - 1.8e-160 531.9 13.6 2.2e-160 531.6 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX86396.1 - 0.033 14.4 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF29 Tup_N PF08581.10 EAX86396.1 - 0.3 11.4 3.8 12 6.3 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX86396.1 - 1.3 9.5 6.8 2.1 8.8 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX86397.1 - 7.4e-157 520.0 13.0 9.3e-157 519.7 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86397.1 - 0.095 12.6 0.9 0.28 11.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX86397.1 - 1.1 9.8 4.0 1.6 9.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Methyltransf_12 PF08242.12 EAX86399.1 - 0.032 15.0 0.5 0.79 10.5 0.1 2.8 2 0 0 2 2 2 0 Methyltransferase domain LRR_4 PF12799.7 EAX86399.1 - 3 8.4 23.0 15 6.2 2.0 7.2 2 2 4 7 7 7 0 Leucine Rich repeats (2 copies) Aldo_ket_red PF00248.21 EAX86400.1 - 3.4e-20 72.4 0.1 4.2e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EAX86401.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BHD_3 PF10405.9 EAX86401.1 - 0.069 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 PPDFL PF15060.6 EAX86403.1 - 1.1e-06 29.1 14.9 4.9 7.7 0.1 5.4 5 0 0 5 5 5 4 Differentiation and proliferation regulator PhoD_N PF16655.5 EAX86403.1 - 1.7e-06 28.5 15.8 3.9 8.1 0.2 5.7 4 2 1 5 5 5 4 PhoD-like phosphatase, N-terminal domain Arm-DNA-bind_4 PF14657.6 EAX86403.1 - 1.2e-05 24.9 0.0 66 3.4 0.0 5.6 5 0 0 5 5 5 0 Arm DNA-binding domain Chordopox_G3 PF06129.12 EAX86403.1 - 0.00018 22.2 10.4 13 6.5 0.1 4.4 4 0 0 4 4 4 0 Chordopoxvirus G3 protein TQ PF18202.1 EAX86403.1 - 0.00019 22.0 41.5 0.8 10.2 3.7 4.5 1 1 3 4 4 4 4 T-Q ester bond containing domain AMP-binding_C_2 PF14535.6 EAX86403.1 - 0.00031 21.0 0.2 78 3.7 0.0 4.5 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain DUF2536 PF10750.9 EAX86403.1 - 0.00054 19.8 2.2 48 3.9 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2536) DUF3416 PF11896.8 EAX86403.1 - 0.0008 19.7 0.3 63 3.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3416) DUF2011 PF09428.10 EAX86403.1 - 0.0063 16.7 19.5 11 6.3 0.2 5.3 5 0 0 5 5 5 0 Fungal protein of unknown function (DUF2011) ETC_C1_NDUFA4 PF04800.12 EAX86403.1 - 0.026 14.7 4.3 1e+02 3.3 0.0 4.3 4 0 0 4 4 4 0 ETC complex I subunit conserved region HYR PF02494.16 EAX86403.1 - 0.11 12.8 18.9 17 5.8 0.5 4.7 4 0 0 4 4 4 0 HYR domain THF_DHG_CYH PF00763.23 EAX86403.1 - 0.13 12.5 3.7 1.7e+02 2.5 0.0 4.2 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3992 PF13157.6 EAX86403.1 - 0.22 12.3 11.2 81 4.1 0.1 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3992) CBM60 PF16841.5 EAX86403.1 - 0.24 11.8 17.8 22 5.6 0.4 4.6 4 0 0 4 4 4 0 Ca-dependent carbohydrate-binding module xylan-binding ANAPC5 PF12862.7 EAX86403.1 - 0.33 11.0 7.4 1.6e+02 2.4 0.0 4.8 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 Adap_comp_sub PF00928.21 EAX86403.1 - 0.38 10.1 17.6 11 5.3 0.6 4.0 1 1 3 4 4 4 0 Adaptor complexes medium subunit family BAT PF15915.5 EAX86403.1 - 0.79 9.6 7.2 1.1e+02 2.6 0.1 4.1 4 0 0 4 4 4 0 GAF and HTH_10 associated domain XdhC_C PF13478.6 EAX86403.1 - 1 9.9 3.3 2.9e+02 2.0 0.0 3.8 1 1 3 4 4 4 0 XdhC Rossmann domain Myosin_N PF02736.19 EAX86403.1 - 2.4 8.1 6.7 4.3e+02 0.8 0.0 5.7 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PQQ PF01011.21 EAX86403.1 - 9.6 6.3 14.0 1e+02 3.1 0.2 5.2 4 0 0 4 4 4 0 PQQ enzyme repeat GPS2_interact PF15784.5 EAX86404.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86404.1 - 0.1 11.5 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86405.1 - 0.033 14.2 8.5 0.051 13.6 8.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86405.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMP PF05017.14 EAX86406.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86407.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX86408.1 - 1.1e-193 627.5 141.6 6.2e-34 115.9 16.3 7.3 4 1 6 10 10 10 7 Phage tail repeat like Apolipoprotein PF01442.18 EAX86408.1 - 0.14 12.0 3.9 1.9 8.3 3.9 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2785 PF10978.8 EAX86408.1 - 0.22 11.3 12.6 1.4 8.6 3.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) DUF1248 PF06852.12 EAX86408.1 - 4 6.9 7.1 3.1 7.2 0.0 3.4 1 1 1 4 4 4 0 Protein of unknown function (DUF1248) DUF4107 PF13389.6 EAX86410.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86410.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF1731 PF08338.11 EAX86412.1 - 0.12 12.2 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Gly_rich PF12810.7 EAX86413.1 - 3e-36 125.6 40.2 3.6e-36 125.3 40.2 1.0 1 0 0 1 1 1 1 Glycine rich protein PDEase_I PF00233.19 EAX86414.1 - 0.00073 19.3 3.0 0.0055 16.5 0.6 2.9 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX86414.1 - 0.0025 18.4 0.0 0.0078 16.8 0.0 1.9 2 0 0 2 2 2 1 GAF domain DUF3839 PF12943.7 EAX86415.1 - 1.3e-157 522.5 12.7 1.5e-157 522.3 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX86415.1 - 0.095 13.1 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86415.1 - 1 9.9 7.8 2.2 8.8 0.7 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SL4P PF17618.2 EAX86416.1 - 0.47 10.5 2.9 5.4 7.1 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX86417.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86418.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PMM PF03332.13 EAX86421.1 - 5.7e-92 307.5 0.7 6.7e-92 307.2 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EAX86421.1 - 7.7e-05 22.6 0.0 0.00086 19.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Med10 PF09748.9 EAX86421.1 - 0.11 12.4 0.3 0.96 9.4 0.1 2.4 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Tnp_22_trimer PF17489.2 EAX86423.1 - 3.1 7.9 6.6 5.4 7.1 1.4 2.4 1 1 1 2 2 2 0 L1 transposable element trimerization domain Trypan_PARP PF05887.11 EAX86424.1 - 0.098 12.6 6.7 0.15 12.0 6.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX86425.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86425.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PSP PF04046.16 EAX86427.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86428.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86429.1 - 0.014 15.9 0.7 0.03 14.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX86430.1 - 1.6e-156 518.9 13.5 2e-156 518.6 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86430.1 - 0.056 13.9 1.5 0.24 11.8 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX86430.1 - 0.34 11.4 6.1 2.2 8.8 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX86431.1 - 1.6e-156 518.9 13.6 2e-156 518.6 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX86431.1 - 0.099 13.1 0.4 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86431.1 - 1.9 9.0 7.8 2.5 8.6 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX86432.1 - 1.8e-36 126.1 15.9 1.1e-35 123.5 15.9 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX86432.1 - 0.084 12.9 1.6 2.2 8.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5065) DUF5106 PF17127.4 EAX86432.1 - 0.093 13.0 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) HSP70 PF00012.20 EAX86434.1 - 4.5e-68 229.9 0.2 5.8e-68 229.5 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX86434.1 - 2.1e-08 33.4 0.1 2.9e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein YmaF PF12788.7 EAX86434.1 - 0.014 15.9 0.4 0.52 10.9 0.1 2.5 2 0 0 2 2 2 0 YmaF family STAR_dimer PF16544.5 EAX86434.1 - 0.033 13.8 0.3 0.069 12.7 0.3 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Phage_fiber PF03335.13 EAX86434.1 - 3.6 8.0 8.2 18 5.8 0.7 3.1 2 0 0 2 2 2 0 Phage tail fibre repeat PSP PF04046.16 EAX86435.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PSP PF04046.16 EAX86437.1 - 0.067 13.1 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86438.1 - 0.062 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX86440.1 - 3.2e-150 498.3 14.7 4e-150 498.0 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86440.1 - 4.7 7.8 8.8 2.3 8.7 1.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX86441.1 - 9.5e-06 26.1 0.2 2.6e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX86441.1 - 0.027 14.0 0.1 3.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain Roc PF08477.13 EAX86442.1 - 1.1e-07 32.0 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX86442.1 - 4.4e-07 29.6 0.0 6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EAX86442.1 - 0.004 17.2 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EAX86442.1 - 0.025 14.1 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX86442.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase DUF3839 PF12943.7 EAX86443.1 - 2.2e-151 502.1 12.4 3e-151 501.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX86443.1 - 0.078 13.4 0.7 1.9 8.9 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86443.1 - 2.1 8.8 5.6 2.6 8.5 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 EAX86444.1 - 0.01 15.9 0.2 0.015 15.4 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX86444.1 - 0.061 13.2 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Tho2 PF11262.8 EAX86444.1 - 0.087 12.0 2.7 0.097 11.9 2.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX86444.1 - 0.38 10.7 8.3 0.13 12.2 2.8 2.6 3 1 0 3 3 3 0 Spo12 family Ras PF00071.22 EAX86445.1 - 1.4e-43 148.3 0.0 1.7e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86445.1 - 2e-23 82.9 0.0 2.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86445.1 - 6.4e-11 42.0 0.0 9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX86445.1 - 5.4e-05 23.2 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX86445.1 - 0.00076 19.1 0.0 0.0021 17.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX86445.1 - 0.0026 17.8 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX86445.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EAX86445.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX86445.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EAX86445.1 - 0.032 14.5 0.0 0.085 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EAX86445.1 - 0.033 13.6 0.0 0.085 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EAX86445.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAX86445.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF4108 PF13390.6 EAX86447.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX86449.1 - 6.5e-07 29.1 2.3 6.5e-07 29.1 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX86449.1 - 5e-05 23.1 0.4 0.45 10.2 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX86449.1 - 6.1e-05 23.3 0.2 0.00045 20.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX86449.1 - 0.0002 21.4 3.9 0.00043 20.3 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86449.1 - 0.00044 20.1 0.1 0.00095 19.0 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86449.1 - 0.0015 18.4 0.9 0.0031 17.3 0.9 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86449.1 - 0.0015 18.2 0.5 0.0097 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86449.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX86449.1 - 0.088 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX86449.1 - 0.09 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX86449.1 - 0.11 12.1 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX86449.1 - 0.12 12.8 0.1 0.77 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX86449.1 - 0.18 12.0 5.1 4.4 7.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX86449.1 - 4 7.7 14.3 1.5 9.0 0.1 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF2666) SHE3 PF17078.5 EAX86450.1 - 0.011 15.5 17.4 0.013 15.2 17.4 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HD_assoc PF13286.6 EAX86450.1 - 0.056 14.0 0.1 0.12 12.9 0.1 1.7 1 1 0 1 1 1 0 Phosphohydrolase-associated domain HIRAN PF08797.11 EAX86450.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.7 2 0 0 2 2 2 0 HIRAN domain SSXT PF05030.12 EAX86450.1 - 0.28 10.9 0.2 0.28 10.9 0.2 3.0 2 1 0 2 2 2 0 SSXT protein (N-terminal region) CENP-F_leu_zip PF10473.9 EAX86450.1 - 1.5 8.8 28.0 3.6 7.6 27.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 EAX86450.1 - 5.6 7.0 26.0 2.3 8.3 19.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus UCH PF00443.29 EAX86451.1 - 0.0034 16.9 0.1 0.0034 16.9 0.1 3.2 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF1151 PF06625.11 EAX86451.1 - 1.2 9.1 11.0 18 5.3 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1151) Trypan_PARP PF05887.11 EAX86452.1 - 0.11 12.5 8.9 0.16 11.9 8.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Shisa PF13908.6 EAX86454.1 - 4.9e-08 33.4 1.5 4.9e-08 33.4 1.5 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator NS3_envE PF02723.14 EAX86454.1 - 0.003 17.6 4.4 0.01 15.9 1.9 2.6 2 0 0 2 2 2 1 Non-structural protein NS3/Small envelope protein E Prominin PF05478.11 EAX86454.1 - 0.0071 14.4 0.3 0.01 13.8 0.3 1.2 1 0 0 1 1 1 1 Prominin SCIMP PF15050.6 EAX86454.1 - 0.083 13.3 0.3 0.2 12.1 0.3 1.6 1 0 0 1 1 1 0 SCIMP protein TMIE PF16038.5 EAX86454.1 - 0.56 10.1 2.9 0.95 9.4 2.9 1.3 1 0 0 1 1 1 0 TMIE protein DUF2749 PF10907.8 EAX86454.1 - 2.1 8.6 5.4 1.2 9.4 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Shisa PF13908.6 EAX86455.1 - 2.6e-08 34.4 1.5 4.9e-08 33.4 1.5 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator NS3_envE PF02723.14 EAX86455.1 - 0.0042 17.1 1.9 0.01 15.9 1.9 1.6 1 0 0 1 1 1 1 Non-structural protein NS3/Small envelope protein E Prominin PF05478.11 EAX86455.1 - 0.0071 14.4 0.3 0.011 13.8 0.3 1.2 1 0 0 1 1 1 1 Prominin AJAP1_PANP_C PF15298.6 EAX86455.1 - 0.028 14.6 0.1 0.028 14.6 0.1 2.7 3 0 0 3 3 3 0 AJAP1/PANP C-terminus SCIMP PF15050.6 EAX86455.1 - 0.081 13.4 0.3 0.2 12.1 0.3 1.6 1 0 0 1 1 1 0 SCIMP protein TMIE PF16038.5 EAX86455.1 - 0.52 10.2 2.9 0.95 9.3 2.9 1.4 1 0 0 1 1 1 0 TMIE protein DUF2749 PF10907.8 EAX86455.1 - 2.4 8.4 5.4 1.2 9.4 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF4108 PF13390.6 EAX86456.1 - 9.9e-63 210.3 7.3 1.1e-62 210.2 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX86456.1 - 0.11 12.7 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Cupin_2 PF07883.11 EAX86457.1 - 0.11 12.2 0.3 51 3.7 0.0 3.3 3 0 0 3 3 3 0 Cupin domain Dzip-like_N PF13815.6 EAX86458.1 - 9.7e-37 125.5 0.1 9.7e-37 125.5 0.1 1.8 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal TBCC_N PF16752.5 EAX86458.1 - 0.0049 17.3 2.3 0.61 10.5 0.1 2.3 1 1 1 2 2 2 2 Tubulin-specific chaperone C N-terminal domain V-SNARE PF05008.15 EAX86458.1 - 0.028 14.8 5.4 0.047 14.1 1.2 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF745 PF05335.13 EAX86458.1 - 0.046 13.5 3.4 0.13 12.0 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 EAX86458.1 - 0.066 13.8 3.3 2.1 9.0 0.8 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TFA2_Winged_2 PF18121.1 EAX86458.1 - 0.12 12.0 0.5 12 5.6 0.0 2.4 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Tropomyosin PF00261.20 EAX86458.1 - 0.22 10.9 8.7 0.33 10.3 8.7 1.2 1 0 0 1 1 1 0 Tropomyosin ALMT PF11744.8 EAX86458.1 - 0.41 9.4 2.2 0.58 8.9 1.9 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter TPR_MLP1_2 PF07926.12 EAX86458.1 - 0.42 10.7 12.2 1.4 9.0 1.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4388 PF14332.6 EAX86459.1 - 0.12 12.6 0.4 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) TMP PF05017.14 EAX86460.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86461.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP UbiA PF01040.18 EAX86462.1 - 0.0027 17.0 8.6 0.0042 16.4 8.6 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Mad3_BUB1_II PF08171.11 EAX86464.1 - 0.047 13.9 0.3 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 AMMECR1 PF01871.17 EAX86465.1 - 4.8e-49 166.2 0.0 5.6e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 RepB-RCR_reg PF10723.9 EAX86465.1 - 0.00064 19.6 0.0 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 Replication regulatory protein RepB DUF1604 PF07713.13 EAX86465.1 - 0.037 13.8 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) ARA70 PF12489.8 EAX86466.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator Apolipoprotein PF01442.18 EAX86466.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF445 PF04286.12 EAX86467.1 - 0.16 11.7 0.3 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Endonuc_Holl PF10107.9 EAX86467.1 - 1.1 9.1 5.2 0.49 10.2 1.2 2.0 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Chromo PF00385.24 EAX86467.1 - 1.3 9.0 8.7 0.18 11.7 3.5 2.4 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain UNC45-central PF11701.8 EAX86470.1 - 0.026 14.5 4.9 0.15 12.0 0.3 2.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central RICTOR_V PF14668.6 EAX86470.1 - 0.032 14.5 0.1 0.14 12.4 0.1 2.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 CAMSAP_CH PF11971.8 EAX86470.1 - 0.22 11.4 1.2 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 CAMSAP CH domain tRNA-synt_1d PF00750.19 EAX86471.1 - 1.4e-22 80.1 4.3 6.8e-12 45.0 0.0 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 EAX86471.1 - 2.5e-15 56.7 0.0 1.8e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 EAX86471.1 - 0.042 13.2 0.1 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EAX86471.1 - 0.05 12.5 0.0 0.6 9.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF4106 PF13388.6 EAX86472.1 - 7.8e-226 750.1 50.3 2.5e-129 432.2 29.7 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX86472.1 - 0.028 14.7 0.1 0.87 9.9 0.1 2.3 2 0 0 2 2 2 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX86472.1 - 0.037 13.8 0.3 0.074 12.9 0.3 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF2897 PF11446.8 EAX86473.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX86474.1 - 3.6e-07 29.9 1.7 3.6e-07 29.9 1.7 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86474.1 - 7.6e-06 26.2 0.2 0.00011 22.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86474.1 - 5e-05 23.1 0.2 0.39 10.4 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86474.1 - 0.00025 21.1 2.4 0.00053 20.0 2.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86474.1 - 0.00086 19.1 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX86474.1 - 0.0018 18.0 0.4 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX86474.1 - 0.0025 17.7 1.0 0.0052 16.6 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX86474.1 - 0.0091 16.3 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX86474.1 - 0.044 14.2 0.1 0.37 11.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX86474.1 - 0.071 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF3783 PF12646.7 EAX86474.1 - 0.079 12.9 1.3 2.4 8.2 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) AAA_25 PF13481.6 EAX86474.1 - 0.081 12.5 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX86474.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86474.1 - 0.39 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX86475.1 - 8.7e-156 516.5 13.7 1.1e-155 516.2 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX86475.1 - 0.025 14.8 1.3 1.3 9.3 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX86475.1 - 0.35 11.3 6.2 1.9 9.0 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX86475.1 - 0.61 10.7 4.1 1.1 9.9 0.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX86476.1 - 1.1e-45 154.1 0.1 2.2e-45 153.1 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAX86476.1 - 0.014 15.6 0.3 0.035 14.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX86477.1 - 1.1e-157 522.8 14.8 1.3e-157 522.4 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX86477.1 - 0.12 13.0 1.4 1.1 9.9 0.1 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5398) NTP_transf_6 PF06042.11 EAX86477.1 - 0.15 11.9 1.7 0.46 10.3 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86477.1 - 1.8 9.1 6.4 1.9 9.0 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX86478.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86482.1 - 0.33 10.8 3.4 0.25 11.2 0.4 2.3 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX86483.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86484.1 - 0.026 15.0 0.5 0.046 14.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX86485.1 - 1.5e-31 108.2 26.1 3.5e-19 68.6 6.8 5.2 5 1 1 6 6 6 3 Phage tail repeat like PH_TFIIH PF08567.11 EAX86485.1 - 0.85 10.0 3.4 5.4 7.4 0.2 3.5 3 1 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain Antimicrobial_1 PF08018.11 EAX86486.1 - 0.21 11.7 0.6 0.47 10.7 0.6 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide Ank_4 PF13637.6 EAX86487.1 - 4.2e-59 196.2 20.2 3.3e-10 40.3 0.1 9.3 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX86487.1 - 9.3e-58 190.3 21.6 1.5e-08 34.7 0.1 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_2 PF12796.7 EAX86487.1 - 6.3e-53 177.3 29.9 3.3e-17 62.8 3.8 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86487.1 - 1.3e-45 152.8 26.8 1.8e-11 44.1 0.8 7.4 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86487.1 - 3.8e-45 146.7 22.2 3.2e-05 24.0 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat DUF3447 PF11929.8 EAX86487.1 - 1.6e-38 130.5 5.3 1.6e-38 130.5 5.3 4.7 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) VirE_N PF08800.10 EAX86487.1 - 0.091 12.9 1.5 24 5.0 0.0 3.6 3 1 1 4 4 4 0 VirE N-terminal domain CCDC84 PF14968.6 EAX86487.1 - 2.8 7.5 5.9 7.5 6.1 5.8 1.8 1 1 0 1 1 1 0 Coiled coil protein 84 SAB PF04382.13 EAX86487.1 - 5.4 7.2 5.5 1.4e+02 2.6 0.1 4.8 6 0 0 6 6 6 0 SAB domain Spc7 PF08317.11 EAX86488.1 - 0.0024 16.8 13.4 0.0024 16.8 13.4 3.1 1 1 2 3 3 3 1 Spc7 kinetochore protein Taxilin PF09728.9 EAX86488.1 - 0.0073 15.5 14.9 0.0073 15.5 14.9 3.3 1 1 0 2 2 2 1 Myosin-like coiled-coil protein GAS PF13851.6 EAX86488.1 - 0.19 11.1 43.5 0.051 12.9 2.4 4.1 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding CdiI_2 PF18593.1 EAX86488.1 - 0.36 11.5 3.9 0.83 10.4 0.2 3.2 3 1 1 4 4 4 0 CdiI immunity protein DUF1664 PF07889.12 EAX86488.1 - 0.48 10.5 26.5 2.2 8.4 3.8 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EAX86488.1 - 0.77 9.0 31.7 0.67 9.2 6.4 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Cep57_MT_bd PF06657.13 EAX86488.1 - 1.8 9.1 16.3 9 6.8 2.4 4.6 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 KfrA_N PF11740.8 EAX86488.1 - 2.4 8.9 7.0 2.4 8.9 1.2 3.0 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term FlaC_arch PF05377.11 EAX86488.1 - 2.5 8.5 0.0 2.5 8.5 0.0 5.5 4 3 3 7 7 7 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EAX86488.1 - 5.8 6.9 31.8 0.61 10.1 2.2 4.2 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 EAX86489.1 - 2.8e-140 457.3 23.4 8e-21 74.4 0.2 10.4 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86489.1 - 1.3e-109 357.2 2.6 5.4e-10 39.6 0.0 15.8 12 5 7 19 19 19 18 Ankyrin repeats (many copies) Ank PF00023.30 EAX86489.1 - 1.7e-105 341.3 30.1 0.00012 22.3 0.1 20.0 20 0 0 20 20 20 19 Ankyrin repeat Ank_5 PF13857.6 EAX86489.1 - 1.5e-98 321.6 21.3 6e-08 32.8 0.1 19.1 1 1 18 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86489.1 - 2.1e-87 276.5 0.9 0.0016 18.8 0.0 19.9 20 0 0 20 20 20 18 Ankyrin repeat T4_Gp59_N PF08993.10 EAX86489.1 - 1.6e-06 28.4 8.6 54 4.3 0.0 10.5 5 4 6 12 12 12 0 T4 gene Gp59 loader of gp41 DNA helicase Vasculin PF15337.6 EAX86489.1 - 2.7e-05 24.9 0.0 41 5.1 0.0 5.5 4 1 1 5 5 5 0 Vascular protein family Vasculin-like 1 FmdA_AmdA PF03069.15 EAX86489.1 - 0.11 11.3 5.3 2.3 7.0 0.3 4.3 1 1 3 5 5 5 0 Acetamidase/Formamidase family Pfk_N PF18468.1 EAX86489.1 - 1.2 9.6 3.5 2.2e+02 2.3 0.0 4.2 4 0 0 4 4 4 0 Phosphofructokinase N-terminal domain yeast GPS2_interact PF15784.5 EAX86490.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86490.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain F5_F8_type_C PF00754.25 EAX86491.1 - 4.3e-06 26.9 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Gly-zipper_Omp PF13488.6 EAX86493.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX86493.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX86493.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TPR_MLP1_2 PF07926.12 EAX86494.1 - 0.035 14.2 0.2 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX86494.1 - 0.085 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX86494.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX86495.1 - 2.4e-156 518.4 13.5 3e-156 518.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX86495.1 - 0.11 12.8 0.4 2 8.8 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX86495.1 - 0.29 11.7 3.4 0.83 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86495.1 - 0.31 11.5 6.7 2 9.0 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX86497.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86498.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF900 PF05990.12 EAX86499.1 - 0.061 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PSP PF04046.16 EAX86500.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86501.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Pkinase PF00069.25 EAX86504.1 - 1.7e-17 63.7 0.0 2.9e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86504.1 - 2.4e-06 27.1 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4107 PF13389.6 EAX86505.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX86506.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX86507.1 - 0.00058 19.8 7.5 0.00066 19.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Trypan_PARP PF05887.11 EAX86508.1 - 0.043 13.8 8.5 0.068 13.1 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_5 PF07728.14 EAX86510.1 - 1.7e-11 44.3 0.0 6.6e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EAX86510.1 - 0.02 13.9 1.2 0.033 13.3 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 EAX86510.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Hydrolase_6 PF13344.6 EAX86510.1 - 0.044 13.9 0.0 3.7 7.7 0.0 3.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Nudc_N PF14050.6 EAX86510.1 - 0.074 13.0 0.2 2.3 8.3 0.2 2.8 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. FAS_N PF17828.1 EAX86511.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAX86512.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86512.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain LIM PF00412.22 EAX86513.1 - 2.3e-21 75.8 79.6 1.6e-08 34.6 8.0 4.4 4 0 0 4 4 4 4 LIM domain WD40 PF00400.32 EAX86514.1 - 2.8e-25 88.1 23.6 0.00012 22.7 0.1 9.4 8 1 1 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX86514.1 - 1.1e-18 67.3 0.3 2.3e-05 24.6 0.1 7.2 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX86514.1 - 6.5e-11 42.1 3.2 0.0074 15.7 0.0 4.3 4 1 0 4 4 4 3 WD40-like domain eIF2A PF08662.11 EAX86514.1 - 1.1e-08 35.3 0.1 0.0022 17.9 0.0 3.7 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EAX86514.1 - 1.1e-05 25.2 0.0 0.087 12.4 0.0 3.2 2 2 1 3 3 3 2 PQQ-like domain Nbas_N PF15492.6 EAX86514.1 - 6.1e-05 22.5 0.0 0.011 15.0 0.0 2.8 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EAX86514.1 - 0.0058 15.3 2.9 0.075 11.7 0.1 3.3 3 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EAX86514.1 - 0.02 15.3 0.4 0.77 10.3 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 EAX86514.1 - 0.038 13.9 0.9 1.5 8.9 0.0 3.9 5 0 0 5 5 5 0 PQQ enzyme repeat Tetraspanin PF00335.20 EAX86515.1 - 0.095 12.4 13.8 0.32 10.7 14.1 1.7 1 1 1 2 2 2 0 Tetraspanin family DUF5353 PF17304.2 EAX86515.1 - 0.096 12.4 0.4 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5353) DUF716 PF04819.12 EAX86515.1 - 0.16 11.6 5.9 0.086 12.5 3.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF716) FHA PF00498.26 EAX86516.1 - 2.1e-11 44.0 0.3 4.1e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 EAX86516.1 - 2.6e-05 24.0 15.9 8.2e-05 22.4 15.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX86516.1 - 0.0015 18.3 14.9 0.005 16.7 14.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAX86516.1 - 0.0034 17.7 17.9 0.0034 17.7 17.9 2.3 2 0 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 EAX86516.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 EAX86516.1 - 0.084 13.1 17.9 0.24 11.6 16.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAX86516.1 - 6.2 6.9 14.4 20 5.3 14.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger T5orf172 PF10544.9 EAX86517.1 - 0.00014 22.3 0.1 0.00038 21.0 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX86517.1 - 0.0054 16.3 0.5 0.14 11.7 0.2 2.0 2 0 0 2 2 2 2 Legume lectin domain Baculo_ME53 PF06061.11 EAX86517.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 DUF3839 PF12943.7 EAX86518.1 - 2.5e-39 135.2 4.6 3.5e-39 134.7 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX86518.1 - 0.1 13.1 0.5 0.57 10.7 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PTR PF12789.7 EAX86520.1 - 1.9e-32 111.1 18.1 8.6e-32 109.0 14.3 4.1 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX86520.1 - 0.048 13.4 0.9 0.086 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX86521.1 - 0.029 14.8 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX86521.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX86522.1 - 0.12 13.1 3.9 16 6.7 0.1 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86523.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP CLASP_N PF12348.8 EAX86524.1 - 7.3e-09 35.5 1.2 1.2e-08 34.8 1.2 1.2 1 0 0 1 1 1 1 CLASP N terminal Nrap_D2 PF17403.2 EAX86524.1 - 0.00072 19.3 0.2 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain TAN PF11640.8 EAX86524.1 - 0.017 15.3 0.6 0.054 13.6 0.6 1.9 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair EcoEI_R_C PF08463.10 EAX86524.1 - 0.078 13.1 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 EcoEI R protein C-terminal Zea_mays_MuDR PF05928.11 EAX86525.1 - 0.19 11.4 0.1 0.43 10.2 0.0 1.6 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) DUF2841 PF11001.8 EAX86526.1 - 0.003 17.6 0.4 0.005 16.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Ima1_N PF09779.9 EAX86526.1 - 3.3 8.6 5.6 2.1 9.2 0.5 2.4 2 1 0 2 2 2 0 Ima1 N-terminal domain Orthoreo_P10 PF07204.11 EAX86527.1 - 0.037 14.0 0.7 0.064 13.2 0.7 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 EAX86527.1 - 0.18 12.0 0.7 0.32 11.2 0.7 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF948 PF06103.11 EAX86528.1 - 0.012 15.9 0.1 0.49 10.7 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.6 EAX86528.1 - 0.015 15.3 3.5 0.032 14.2 0.9 2.0 1 1 0 2 2 2 0 FlxA-like protein HOOK PF05622.12 EAX86528.1 - 0.016 13.4 4.6 0.018 13.2 4.6 1.0 1 0 0 1 1 1 0 HOOK protein SKA2 PF16740.5 EAX86528.1 - 0.033 14.0 2.8 0.17 11.7 2.8 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 LPP PF04728.13 EAX86528.1 - 0.074 13.5 0.9 6.4 7.2 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DHR10 PF18595.1 EAX86528.1 - 0.075 13.1 3.0 0.21 11.7 1.8 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF1515 PF07439.11 EAX86528.1 - 0.085 12.9 1.8 0.4 10.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Perilipin PF03036.16 EAX86528.1 - 0.087 11.8 0.6 0.14 11.1 0.4 1.2 1 1 0 1 1 1 0 Perilipin family V_ATPase_I PF01496.19 EAX86528.1 - 0.2 9.5 2.4 0.23 9.3 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 EAX86528.1 - 0.29 11.3 4.5 0.72 10.0 2.6 2.0 1 1 1 2 2 2 0 Tropomyosin like zf-C4H2 PF10146.9 EAX86528.1 - 0.67 10.2 3.1 9.2 6.5 0.5 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.9 EAX86528.1 - 0.82 10.0 4.7 5.4 7.4 0.1 2.5 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ANAPC4_WD40 PF12894.7 EAX86529.1 - 1.8e-10 41.0 0.0 1.5e-09 38.1 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4107 PF13389.6 EAX86531.1 - 1.5e-72 243.0 3.8 2e-72 242.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX86532.1 - 1.2e-191 637.5 18.7 1.2e-191 637.5 18.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX86532.1 - 0.086 12.6 0.1 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DUF1722 PF08349.11 EAX86532.1 - 0.18 12.1 3.6 13 6.1 0.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) FapA PF03961.13 EAX86532.1 - 0.26 9.8 3.5 0.42 9.1 3.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PSP PF04046.16 EAX86533.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86534.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX86536.1 - 3.7e-157 521.0 14.4 4.7e-157 520.7 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86536.1 - 0.041 14.3 1.1 0.11 13.0 0.2 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX86536.1 - 0.13 12.1 2.0 0.32 10.8 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX86536.1 - 0.56 10.7 5.9 7.3 7.1 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX86537.1 - 0.00024 21.6 0.1 0.00056 20.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX86538.1 - 2.2e-155 515.2 12.6 2.7e-155 514.9 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86538.1 - 0.14 12.0 1.0 0.46 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX86538.1 - 0.71 10.2 3.0 0.59 10.5 0.2 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Pox_A32 PF04665.12 EAX86539.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX86539.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX86539.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX86539.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) AAA_22 PF13401.6 EAX86540.1 - 0.00089 19.5 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX86540.1 - 0.0038 17.1 0.0 0.0042 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX86540.1 - 0.0061 16.6 0.0 0.0081 16.2 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAX86540.1 - 0.0087 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX86540.1 - 0.021 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX86540.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DctM PF06808.12 EAX86540.1 - 0.066 12.0 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component DUF2897 PF11446.8 EAX86541.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RIIa PF02197.17 EAX86542.1 - 1.6e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MHB PF16525.5 EAX86542.1 - 0.066 13.5 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding F_bP_aldolase PF01116.20 EAX86543.1 - 2.6e-92 309.3 0.0 3.3e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II T5orf172 PF10544.9 EAX86544.1 - 2.5e-06 27.9 0.1 5.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX86544.1 - 0.015 15.2 1.6 0.11 12.4 0.8 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAX86544.1 - 0.097 13.6 0.1 1.2 10.1 0.0 2.2 2 0 0 2 2 2 0 FRG domain DUF3839 PF12943.7 EAX86545.1 - 8.1e-153 506.8 12.6 9.9e-153 506.5 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86545.1 - 0.047 14.1 2.2 0.054 13.9 0.4 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX86545.1 - 0.37 11.3 6.4 2.4 8.7 0.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX86546.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Myb_DNA-binding PF00249.31 EAX86547.1 - 1.4e-20 73.1 0.0 9.4e-17 60.9 0.0 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86547.1 - 4.1e-20 71.8 0.0 5.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EAX86547.1 - 0.023 14.7 0.0 0.23 11.5 0.0 2.0 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_2 PF08914.11 EAX86547.1 - 0.093 12.9 0.1 2.2 8.6 0.0 2.5 1 1 1 2 2 2 0 Rap1 Myb domain TPR_12 PF13424.6 EAX86548.1 - 0.00022 21.4 0.8 0.026 14.8 0.0 2.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX86548.1 - 0.00075 19.5 0.6 6.5 7.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAX86548.1 - 0.0031 16.9 0.6 0.0094 15.4 0.0 2.2 3 0 0 3 3 3 1 SHNi-TPR TPR_14 PF13428.6 EAX86548.1 - 0.026 15.3 0.4 5.2 8.2 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2982 PF11201.8 EAX86548.1 - 0.04 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) TPR_2 PF07719.17 EAX86548.1 - 2.6 8.4 6.8 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EAX86550.1 - 3.5e-21 75.2 11.8 4.7e-21 74.8 11.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAX86550.1 - 1.7e-14 53.6 10.4 2.4e-14 53.1 10.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAX86550.1 - 1.6e-08 34.7 17.1 4.4e-07 30.1 17.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX86550.1 - 1.1e-05 25.3 12.9 4.7e-05 23.2 12.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX86550.1 - 0.00012 21.9 18.2 0.02 14.7 18.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX86550.1 - 0.00048 19.9 8.5 0.002 17.9 6.5 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EAX86550.1 - 0.0012 18.6 7.9 0.0012 18.6 7.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAX86550.1 - 0.024 14.6 11.6 0.41 10.6 9.7 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAX86550.1 - 0.046 13.7 12.4 0.32 11.0 12.4 2.5 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EAX86550.1 - 0.084 12.5 15.1 0.38 10.4 10.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EAX86550.1 - 0.29 11.5 11.6 1.1 9.7 11.6 1.9 1 1 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 EAX86550.1 - 0.39 10.9 8.3 9.7 6.4 8.2 2.5 1 1 1 2 2 2 0 KIAA1045 RING finger FANCL_C PF11793.8 EAX86550.1 - 3.2 8.0 11.4 16 5.7 11.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EAX86550.1 - 4.2 7.2 15.5 1.1e+02 2.7 15.5 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EAX86550.1 - 5.8 7.1 12.4 0.35 11.0 3.2 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EAX86550.1 - 7 6.9 12.7 0.21 11.8 1.8 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Fer2 PF00111.27 EAX86552.1 - 2e-09 37.3 3.4 2.4e-09 37.0 3.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Porin_3 PF01459.22 EAX86553.1 - 7.1e-07 28.9 0.3 2.5e-06 27.2 0.0 1.9 2 1 1 3 3 3 1 Eukaryotic porin Adap_comp_sub PF00928.21 EAX86554.1 - 1.7e-48 165.3 0.0 2.1e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EAX86554.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF4369 PF14289.6 EAX86554.1 - 0.0043 17.5 0.1 5.3 7.6 0.0 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF4369) Clat_adaptor_s PF01217.20 EAX86554.1 - 0.038 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Mrr_cat PF04471.12 EAX86554.1 - 0.15 12.1 0.1 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease Trypan_PARP PF05887.11 EAX86557.1 - 0.028 14.4 8.3 0.045 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86557.1 - 1.8 9.0 5.2 2.6 8.5 5.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX86558.1 - 0.1 11.6 0.1 0.094 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX86560.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX86561.1 - 0.059 13.1 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Pox_A32 PF04665.12 EAX86562.1 - 3.9e-07 29.8 2.6 3.9e-07 29.8 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86562.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86562.1 - 5.5e-05 23.0 0.3 0.47 10.2 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86562.1 - 0.00016 21.7 3.4 0.00039 20.5 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86562.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86562.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86562.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86562.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX86562.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86562.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86562.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86562.1 - 0.38 11.0 4.4 7.8 6.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX86563.1 - 3.2e-35 120.4 0.7 6.2e-35 119.4 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86563.1 - 0.0045 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Parathyroid hormone family DUF3839 PF12943.7 EAX86564.1 - 4.2e-156 517.5 12.8 5.4e-156 517.2 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86564.1 - 2.5 8.6 6.1 5 7.7 0.3 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86564.1 - 2.7 8.5 5.4 2.2 8.9 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAX86565.1 - 1.7e-73 246.2 4.4 2e-73 245.9 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86565.1 - 0.15 10.5 1.0 0.21 10.0 1.0 1.1 1 0 0 1 1 1 0 Lipoxygenase PSP PF04046.16 EAX86567.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86568.1 - 0.066 13.8 4.9 12 7.1 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86569.1 - 0.029 14.9 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX86569.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein T5orf172 PF10544.9 EAX86570.1 - 2.7e-05 24.6 0.4 7.6e-05 23.2 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX86570.1 - 0.0017 17.9 0.5 0.17 11.4 0.2 2.1 2 0 0 2 2 2 2 Legume lectin domain Amidase02_C PF12123.8 EAX86571.1 - 0.0034 17.0 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86572.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86572.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase GPS2_interact PF15784.5 EAX86574.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86574.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86575.1 - 0.3 11.1 10.6 0.32 11.0 10.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86575.1 - 4.8 7.6 6.1 5.5 7.4 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX86577.1 - 2.2e-41 140.2 0.6 6e-41 138.8 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX86577.1 - 0.011 15.0 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX86577.1 - 0.19 12.3 2.1 1.9 9.1 0.4 2.5 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Pox_A32 PF04665.12 EAX86578.1 - 1.7e-05 24.4 2.2 1.7e-05 24.4 2.2 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86578.1 - 2.5e-05 24.6 0.2 0.00019 21.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86578.1 - 3.6e-05 23.6 0.2 0.29 10.8 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86578.1 - 0.00013 22.1 3.2 0.00026 21.0 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86578.1 - 0.00051 19.8 0.1 0.00097 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86578.1 - 0.0012 18.7 0.5 0.0027 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86578.1 - 0.0015 18.2 0.4 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86578.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX86578.1 - 0.057 13.0 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86578.1 - 0.067 13.6 0.1 0.59 10.6 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 EAX86578.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX86578.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX86578.1 - 0.11 12.5 0.8 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX86578.1 - 0.4 11.0 4.4 9 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) RGS12_us1 PF16613.5 EAX86579.1 - 0.31 11.4 3.4 0.52 10.6 3.4 1.4 1 0 0 1 1 1 0 Unstructured region of RGS12 DUF4108 PF13390.6 EAX86580.1 - 3.1e-61 205.5 8.1 3.5e-61 205.3 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GCV_H PF01597.19 EAX86583.1 - 4.3e-32 110.6 0.4 4.8e-32 110.4 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EAX86583.1 - 0.00042 20.1 0.6 0.00079 19.2 0.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 EAX86583.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain COX15-CtaA PF02628.15 EAX86584.1 - 0.044 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Rft-1 PF04506.13 EAX86585.1 - 9e-61 206.2 24.9 3.2e-60 204.4 24.9 1.8 1 1 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 EAX86585.1 - 7.5 6.6 32.4 0.44 10.6 15.4 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain RRM_1 PF00076.22 EAX86586.1 - 7.8e-17 60.9 0.0 1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX86586.1 - 0.0003 20.6 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif DNA_topoisoIV PF00521.20 EAX86586.1 - 0.013 14.4 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RRM_Rrp7 PF17799.1 EAX86586.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DUF1866 PF08952.11 EAX86586.1 - 0.21 11.4 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) ATG13 PF10033.9 EAX86587.1 - 2.1e-10 40.7 2.1 6.8e-08 32.5 0.5 2.9 2 1 0 2 2 2 2 Autophagy-related protein 13 eIF_4EBP PF05456.11 EAX86587.1 - 0.077 12.9 0.6 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Dzip-like_N PF13815.6 EAX86588.1 - 1e-05 25.5 2.7 1e-05 25.5 2.7 3.4 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-met PF12874.7 EAX86588.1 - 0.0038 17.6 0.2 0.013 15.9 0.2 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAX86588.1 - 0.0089 16.3 0.4 0.0089 16.3 0.4 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAX86588.1 - 0.015 16.1 1.3 0.042 14.7 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX86588.1 - 0.069 13.6 1.5 0.18 12.3 1.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAX86588.1 - 1.4 9.3 8.4 0.53 10.6 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2203 PF09969.9 EAX86588.1 - 7.6 7.3 15.6 0.066 13.9 2.8 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) NDUFB10 PF10249.9 EAX86590.1 - 0.051 14.1 0.6 12 6.4 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 DUF2559 PF10832.8 EAX86590.1 - 0.12 12.4 0.0 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Ank_2 PF12796.7 EAX86592.1 - 1.6e-50 169.6 4.4 3.6e-18 65.9 0.0 6.4 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86592.1 - 5.6e-38 128.5 0.4 1.1e-13 51.2 0.0 6.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX86592.1 - 1.2e-36 123.5 0.0 5.2e-05 23.5 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 EAX86592.1 - 5.7e-36 122.4 5.2 7.7e-07 29.6 0.0 9.7 3 3 7 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86592.1 - 3.1e-35 116.2 2.9 3.9e-06 26.8 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat DUF3447 PF11929.8 EAX86592.1 - 9.9e-24 83.1 5.2 9.9e-24 83.1 5.2 4.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) PEGA PF08308.11 EAX86592.1 - 0.078 12.9 0.0 2.7 8.0 0.0 3.3 5 0 0 5 5 5 0 PEGA domain Peptidase_M60 PF13402.6 EAX86593.1 - 6.6e-52 176.7 3.4 6.6e-52 176.7 3.4 1.6 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like PA14 PF07691.12 EAX86593.1 - 0.0063 16.3 0.3 0.016 15.0 0.3 1.7 1 0 0 1 1 1 1 PA14 domain Big_9 PF17963.1 EAX86593.1 - 0.039 14.7 2.6 0.21 12.3 0.0 3.3 4 0 0 4 4 4 0 Bacterial Ig domain DUF1180 PF06679.12 EAX86593.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1508 PF07411.12 EAX86593.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) DUF1387 PF07139.11 EAX86593.1 - 1.6 8.4 6.1 2.5 7.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PTR PF12789.7 EAX86594.1 - 1.6e-33 114.5 18.9 3.1e-33 113.6 15.0 4.2 3 2 1 4 4 4 2 Phage tail repeat like DUF4057 PF13266.6 EAX86594.1 - 0.023 14.4 0.2 0.051 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) DUF4116 PF13475.6 EAX86594.1 - 0.024 14.4 0.1 0.078 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX86594.1 - 0.087 13.1 1.7 0.38 11.0 0.0 2.7 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain DUF3839 PF12943.7 EAX86595.1 - 3e-99 331.4 5.0 3.4e-99 331.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4107 PF13389.6 EAX86596.1 - 3.4e-53 180.1 9.2 2.1e-51 174.3 9.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) RPA_C PF08784.11 EAX86597.1 - 0.0005 20.7 0.0 0.00079 20.1 0.0 1.3 1 1 0 1 1 1 1 Replication protein A C terminal PqqD PF05402.12 EAX86597.1 - 0.046 14.0 0.4 13 6.2 0.1 2.2 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DDR PF08841.10 EAX86598.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX86598.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX86599.1 - 0.27 11.2 7.6 0.32 11.0 7.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) T5orf172 PF10544.9 EAX86600.1 - 0.0001 22.8 0.2 0.00024 21.6 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX86600.1 - 0.093 12.2 0.6 1.4 8.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX86601.1 - 2.3e-153 508.6 13.4 2.8e-153 508.3 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86601.1 - 0.22 11.3 2.1 0.54 10.1 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX86601.1 - 1.1 9.9 5.5 0.58 10.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86601.1 - 1.3 9.5 7.4 3.4 8.2 0.9 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX86603.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86604.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX86605.1 - 4.5e-05 23.0 2.5 4.5e-05 23.0 2.5 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86605.1 - 0.0024 17.9 0.2 0.0071 16.4 0.2 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX86605.1 - 0.0076 15.8 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX86605.1 - 0.045 14.0 1.0 0.14 12.5 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX86605.1 - 0.058 12.6 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Kinesin PF00225.23 EAX86606.1 - 2e-73 247.2 0.0 3.3e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAX86606.1 - 1.3e-19 70.7 2.7 2.5e-19 69.7 0.1 2.5 3 0 0 3 3 3 1 Microtubule binding Uso1_p115_C PF04871.13 EAX86606.1 - 0.0029 18.0 3.2 0.0093 16.3 3.2 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Secretin PF00263.21 EAX86606.1 - 0.04 13.6 2.3 0.76 9.4 0.1 3.0 3 0 0 3 3 3 0 Bacterial type II and III secretion system protein UPF0242 PF06785.11 EAX86606.1 - 0.093 12.8 11.1 0.2 11.7 11.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rx_N PF18052.1 EAX86606.1 - 0.17 12.2 1.8 4 7.8 1.2 2.6 1 1 1 2 2 2 0 Rx N-terminal domain IL5 PF02025.15 EAX86606.1 - 0.2 12.0 3.2 1.8 8.9 0.0 3.0 2 1 0 2 2 2 0 Interleukin 5 FapA PF03961.13 EAX86606.1 - 0.51 8.9 9.4 1.1 7.7 9.4 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4559 PF15112.6 EAX86606.1 - 1 8.9 6.8 1.7 8.3 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TolA_bind_tri PF16331.5 EAX86606.1 - 6.9 6.8 10.8 0.57 10.3 3.1 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation DENN PF02141.21 EAX86607.1 - 3.2e-15 56.5 5.4 1.1e-14 54.8 4.0 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain Sulfotransfer_1 PF00685.27 EAX86607.1 - 0.011 15.2 0.2 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 Sulfotransferase domain DUF563 PF04577.14 EAX86608.1 - 3.7e-35 122.0 0.4 5e-35 121.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) zf-CCHC_2 PF13696.6 EAX86608.1 - 0.099 12.5 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 Zinc knuckle DMSP_lyase PF16867.5 EAX86608.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Sugar_tr PF00083.24 EAX86609.1 - 5.7e-51 173.8 26.2 5.7e-50 170.5 26.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX86609.1 - 4.1e-24 85.2 51.4 2.1e-18 66.4 26.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX86609.1 - 2.1e-06 26.6 12.4 0.00031 19.4 2.8 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein VIT1 PF01988.19 EAX86609.1 - 1.2 8.9 8.8 3 7.7 2.6 3.1 2 1 1 3 3 3 0 VIT family DDE_1 PF03184.19 EAX86610.1 - 4.3e-09 36.3 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PTR PF12789.7 EAX86611.1 - 2.7e-31 107.4 10.5 2.7e-31 107.4 10.5 3.2 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX86611.1 - 0.0063 16.2 0.1 0.021 14.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX86611.1 - 6 6.8 10.5 1.2 9.1 1.2 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX86612.1 - 0.022 15.2 0.6 0.046 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86613.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86614.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP YIF1 PF03878.15 EAX86615.1 - 1.6e-24 86.7 9.6 1.9e-24 86.5 9.6 1.0 1 0 0 1 1 1 1 YIF1 DDR PF08841.10 EAX86618.1 - 0.074 12.0 0.1 0.076 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX86619.1 - 9.5e-139 460.7 9.9 1.5e-138 460.1 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86619.1 - 0.029 14.8 3.1 0.034 14.6 0.7 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX86619.1 - 0.68 10.4 6.7 5.1 7.6 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86619.1 - 2 9.0 5.7 0.48 11.0 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX86619.1 - 9.1 6.7 9.7 17 5.8 0.5 4.1 3 2 2 5 5 5 0 Tup N-terminal PTR PF12789.7 EAX86620.1 - 8.2e-37 125.1 23.3 1.3e-33 114.8 15.4 5.2 4 2 2 6 6 5 2 Phage tail repeat like Pox_A32 PF04665.12 EAX86621.1 - 1.4e-07 31.2 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX86621.1 - 0.0032 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX86621.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX86621.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX86621.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX86621.1 - 0.53 10.5 8.3 5.8 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAX86623.1 - 7.4e-32 109.5 1.0 1.2e-31 108.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86623.1 - 0.0036 17.9 0.1 0.0097 16.5 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family DUF3839 PF12943.7 EAX86624.1 - 2.4e-156 518.3 15.5 3.1e-156 518.0 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86624.1 - 0.08 12.8 1.3 0.24 11.2 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Fez1 PF06818.15 EAX86624.1 - 0.091 13.2 1.9 0.15 12.5 0.3 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX86624.1 - 0.22 12.0 7.0 0.83 10.2 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX86625.1 - 0.023 15.2 0.8 0.039 14.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86626.1 - 0.066 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86627.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MIP-T3 PF10243.9 EAX86628.1 - 0.13 12.3 1.6 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain Drf_FH1 PF06346.12 EAX86629.1 - 7.8e-06 25.7 86.9 0.19 11.4 15.4 5.5 2 2 3 5 5 5 5 Formin Homology Region 1 Orn_Arg_deC_N PF02784.16 EAX86630.1 - 7e-66 222.1 0.0 8.8e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EAX86630.1 - 5.4e-12 45.8 0.0 5.9e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Matrix PF00661.21 EAX86630.1 - 0.016 13.9 0.0 2.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Viral matrix protein AP_endonuc_2 PF01261.24 EAX86630.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3839 PF12943.7 EAX86631.1 - 1.8e-150 499.1 10.5 2.2e-150 498.8 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86631.1 - 0.0064 17.0 0.5 0.089 13.2 0.0 2.1 2 0 0 2 2 2 1 Fez1 GCN5L1 PF06320.13 EAX86631.1 - 0.028 14.6 0.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) KELK PF15796.5 EAX86631.1 - 0.27 11.7 5.4 1.7 9.2 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX86632.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX86633.1 - 7.8e-155 513.4 13.5 9.9e-155 513.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX86633.1 - 0.15 12.5 0.4 0.15 12.5 0.4 2.4 3 0 0 3 3 3 0 Cell division protein ZapB KELK PF15796.5 EAX86633.1 - 0.35 11.4 6.7 2 9.0 0.6 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tho2 PF11262.8 EAX86634.1 - 0.12 11.5 3.5 0.13 11.4 3.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3447 PF11929.8 EAX86635.1 - 3.5e-19 68.5 7.8 2.7e-18 65.7 7.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3447) SAM_Exu PF18609.1 EAX86635.1 - 0.11 12.7 0.1 0.53 10.4 0.1 2.0 1 1 1 2 2 2 0 Exuperantia SAM-like domain Ank PF00023.30 EAX86636.1 - 2.9e-65 214.0 8.2 2e-10 40.6 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 EAX86636.1 - 1.7e-64 213.4 12.6 1e-12 48.3 0.0 8.0 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86636.1 - 7.2e-56 179.6 9.7 9.5e-08 31.8 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_2 PF12796.7 EAX86636.1 - 7.8e-56 186.6 16.8 2.9e-19 69.4 2.1 5.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86636.1 - 1e-44 150.0 4.9 1.2e-10 41.4 0.1 7.4 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX86636.1 - 0.00063 19.5 0.1 0.93 9.2 0.0 3.3 1 1 0 2 2 2 2 Colon cancer-associated protein Mic1-like Ribosomal_S6 PF01250.17 EAX86636.1 - 0.00069 19.8 0.3 5.6 7.3 0.0 3.7 2 1 2 4 4 4 2 Ribosomal protein S6 HEM4 PF02602.15 EAX86636.1 - 0.0071 15.7 0.0 1.9 7.8 0.0 2.9 2 1 1 3 3 3 1 Uroporphyrinogen-III synthase HemD CHASE9 PF17153.4 EAX86636.1 - 0.043 13.9 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular RNase_PH_C PF03725.15 EAX86636.1 - 0.13 12.3 0.0 7.1 6.7 0.0 3.4 4 0 0 4 4 4 0 3' exoribonuclease family, domain 2 DUF249 PF03158.13 EAX86636.1 - 0.34 10.6 4.9 8.3 6.1 0.3 3.8 2 1 1 3 3 3 0 Multigene family 530 protein CCDC84 PF14968.6 EAX86636.1 - 0.44 10.1 4.1 47 3.5 0.4 3.9 1 1 2 3 3 3 0 Coiled coil protein 84 Thioredoxin PF00085.20 EAX86637.1 - 1.4e-14 53.9 0.1 3.3e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 EAX86637.1 - 1.8e-06 28.0 0.2 5.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain DIM1 PF02966.16 EAX86637.1 - 8.2e-05 22.4 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 UBA PF00627.31 EAX86637.1 - 0.025 14.5 2.5 1.1 9.2 0.0 3.1 4 0 0 4 4 4 0 UBA/TS-N domain DUF3527 PF12043.8 EAX86637.1 - 0.034 13.7 5.5 0.053 13.1 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) PEHE PF15275.6 EAX86637.1 - 7.1 7.3 13.8 0.61 10.7 7.9 2.1 2 1 0 2 2 2 0 PEHE domain HAP1_N PF04849.13 EAX86638.1 - 0.00087 18.6 1.9 0.00089 18.5 1.9 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DivIC PF04977.15 EAX86638.1 - 0.0074 16.0 7.1 0.0087 15.8 5.8 1.7 1 1 1 2 2 2 1 Septum formation initiator Ax_dynein_light PF10211.9 EAX86638.1 - 0.021 14.8 4.7 0.024 14.6 4.7 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain APG6_N PF17675.1 EAX86638.1 - 0.028 14.9 4.9 0.033 14.7 4.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 EAX86638.1 - 0.12 13.0 5.5 0.19 12.4 2.2 2.1 1 1 1 2 2 2 0 SlyX YabA PF06156.13 EAX86638.1 - 0.13 12.9 1.8 0.16 12.6 1.8 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EAX86638.1 - 0.17 12.4 7.4 0.26 11.8 7.4 1.4 1 1 0 1 1 1 0 Cell division protein ZapB E2F_TDP PF02319.20 EAX86640.1 - 8.2e-16 57.8 1.5 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HTH_28 PF13518.6 EAX86640.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ABC2_membrane_6 PF06182.11 EAX86641.1 - 0.026 14.3 0.8 0.05 13.4 0.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Aft1_OSA PF11785.8 EAX86642.1 - 0.13 12.7 0.7 0.33 11.4 0.7 1.6 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain MULE PF10551.9 EAX86643.1 - 4.3e-09 36.7 0.1 1.4e-08 35.0 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain WRKY PF03106.15 EAX86643.1 - 0.023 14.9 2.9 0.05 13.8 0.7 2.5 1 1 1 2 2 2 0 WRKY DNA -binding domain EpuA PF11772.8 EAX86644.1 - 0.022 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF2101 PF09874.9 EAX86645.1 - 0.06 13.0 1.4 0.11 12.2 1.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) IFRD PF05004.13 EAX86645.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF4107 PF13389.6 EAX86646.1 - 4.2e-34 118.1 2.2 6.1e-34 117.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PhoLip_ATPase_C PF16212.5 EAX86649.1 - 0.004 17.0 15.3 0.21 11.3 12.8 2.0 1 1 1 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Tetraspanin PF00335.20 EAX86649.1 - 2.3 7.9 21.0 11 5.6 21.0 2.0 1 1 0 1 1 1 0 Tetraspanin family Thioredoxin PF00085.20 EAX86650.1 - 7.7e-22 77.2 0.0 2.8e-16 59.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 EAX86650.1 - 2.3e-05 24.6 0.1 8.2 6.8 0.0 4.4 3 1 1 4 4 4 1 Thioredoxin-like OST3_OST6 PF04756.13 EAX86650.1 - 2.3e-05 23.9 0.1 7.3e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAX86650.1 - 9.7e-05 22.8 0.5 0.55 10.7 0.1 3.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EAX86650.1 - 0.0035 17.3 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EAX86650.1 - 0.0037 17.0 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EAX86650.1 - 0.0066 16.3 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 EAX86650.1 - 0.087 12.5 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Redoxin Gly-zipper_Omp PF13488.6 EAX86652.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX86652.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX86652.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PTR PF12789.7 EAX86653.1 - 9.2e-11 41.6 5.1 9.2e-11 41.6 5.1 4.6 6 0 0 6 6 6 1 Phage tail repeat like YmaF PF12788.7 EAX86653.1 - 0.0075 16.8 3.9 1.2 9.7 0.0 3.5 3 0 0 3 3 3 1 YmaF family DUF4116 PF13475.6 EAX86653.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Goodbye PF17109.5 EAX86653.1 - 0.79 10.2 2.3 5.3 7.5 0.2 2.7 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF1493 PF07377.12 EAX86654.1 - 0.094 13.2 0.7 0.24 11.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86655.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86656.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Adeno_E3_CR2 PF02439.15 EAX86657.1 - 7.9e-05 22.3 2.3 0.00013 21.7 2.3 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EAX86657.1 - 0.00075 19.6 0.0 0.00096 19.3 0.0 1.2 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 EAX86657.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Glycophorin_A PF01102.18 EAX86657.1 - 0.0033 17.6 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 EAX86657.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PTP_tm PF18861.1 EAX86657.1 - 0.047 13.7 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Chordopox_A13L PF05961.11 EAX86657.1 - 0.066 13.5 1.2 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein ODV-E18 PF10717.9 EAX86657.1 - 0.12 12.3 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Mid2 PF04478.12 EAX86657.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 EAX86657.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless TPPK_C PF12555.8 EAX86657.1 - 0.2 11.7 1.3 0.3 11.2 1.3 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF5385 PF17359.2 EAX86657.1 - 0.5 9.9 2.5 0.91 9.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF4690 PF15756.5 EAX86657.1 - 6.8 7.4 6.2 6.6 7.4 4.6 1.9 1 1 1 2 2 2 0 Small Novel Rich in Cartilage Ras PF00071.22 EAX86658.1 - 6.8e-44 149.3 0.1 8e-44 149.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86658.1 - 4.2e-19 68.9 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86658.1 - 7.4e-13 48.3 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX86658.1 - 1.5e-06 27.9 0.1 3.1e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX86658.1 - 3.8e-05 23.2 0.1 6.9e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX86658.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EAX86658.1 - 0.024 13.8 0.2 0.64 9.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EAX86658.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF948 PF06103.11 EAX86660.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GAIN_A PF18619.1 EAX86660.1 - 0.12 12.6 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Ank_2 PF12796.7 EAX86661.1 - 3.8e-30 104.3 4.4 1.8e-13 50.8 0.4 4.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86661.1 - 5.1e-26 90.7 3.8 1.9e-11 44.2 0.0 5.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86661.1 - 3.3e-25 87.8 4.7 2.1e-07 31.1 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86661.1 - 5.9e-21 72.3 3.1 0.00036 20.8 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EAX86661.1 - 5.5e-15 55.1 2.4 0.00014 22.1 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat DUF3839 PF12943.7 EAX86662.1 - 1.3e-152 506.1 13.8 1.7e-152 505.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86662.1 - 0.042 13.7 0.5 0.1 12.5 0.3 1.7 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX86662.1 - 0.15 12.5 4.6 0.43 11.1 0.5 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86662.1 - 0.17 12.2 2.7 15 6.0 0.0 3.4 3 1 0 3 3 3 0 Tup N-terminal DUF2408 PF10303.9 EAX86662.1 - 1.2 9.7 4.5 0.63 10.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) LRR_8 PF13855.6 EAX86663.1 - 7.3e-14 51.3 22.3 3.5e-07 29.9 0.1 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX86663.1 - 7.9e-10 38.8 32.0 0.00012 22.3 0.2 6.1 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX86663.1 - 0.00096 18.7 7.9 0.1 12.1 0.6 3.5 2 1 1 3 3 3 2 Leucine-rich repeat MarR_2 PF12802.7 EAX86663.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 MarR family LRR_1 PF00560.33 EAX86663.1 - 8.6 7.4 20.2 32 5.6 1.1 7.1 7 1 1 8 8 8 0 Leucine Rich Repeat SOGA PF11365.8 EAX86665.1 - 0.038 15.1 0.3 0.052 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein SOGA DUF5623 PF18536.1 EAX86665.1 - 0.064 13.6 0.2 0.088 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX86665.1 - 0.41 10.6 7.1 0.17 11.8 2.9 2.3 3 1 0 3 3 3 0 Spo12 family DUF3447 PF11929.8 EAX86667.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 3.5 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX86667.1 - 0.00019 22.0 0.4 0.03 14.9 0.4 3.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX86667.1 - 0.017 15.6 0.1 14 6.6 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Vps4_C PF09336.10 EAX86667.1 - 0.018 15.1 0.1 0.07 13.1 0.1 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Ank_4 PF13637.6 EAX86667.1 - 0.028 15.0 0.1 16 6.2 0.0 3.6 1 1 4 5 5 5 0 Ankyrin repeats (many copies) DUF745 PF05335.13 EAX86667.1 - 0.21 11.3 3.3 0.089 12.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) EMP70 PF02990.16 EAX86668.1 - 3.1e-29 102.1 14.7 3.8e-29 101.7 14.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2684 PF10885.8 EAX86668.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2684) DUF4149 PF13664.6 EAX86668.1 - 6 7.2 14.0 0.15 12.4 4.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) PPR_3 PF13812.6 EAX86669.1 - 0.084 13.0 0.5 1.9 8.6 0.0 2.4 2 1 0 2 2 2 0 Pentatricopeptide repeat domain PAS_9 PF13426.7 EAX86671.1 - 0.00091 19.4 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EAX86671.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold Amnionless PF14828.6 EAX86671.1 - 0.19 10.5 1.3 9.8 4.9 0.1 3.2 3 0 0 3 3 3 0 Amnionless EF-hand_6 PF13405.6 EAX86672.1 - 2.4e-13 48.8 11.9 0.012 15.5 0.1 9.0 8 0 0 8 8 8 3 EF-hand domain EF-hand_8 PF13833.6 EAX86672.1 - 3.1e-08 33.3 2.2 1 9.3 0.0 6.8 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 EAX86672.1 - 8.4e-08 31.2 1.5 0.019 14.5 0.0 6.4 7 0 0 7 7 7 2 EF hand EF-hand_7 PF13499.6 EAX86672.1 - 1.8e-07 31.5 25.5 0.069 13.6 0.2 8.7 8 0 0 8 8 8 4 EF-hand domain pair EF-hand_11 PF08976.11 EAX86672.1 - 0.00033 21.5 16.2 20 6.1 0.1 7.4 6 1 2 8 8 8 1 EF-hand domain RlaP PF10127.9 EAX86672.1 - 0.043 13.4 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family DUF3106 PF11304.8 EAX86672.1 - 1.5 9.3 7.6 7.5 7.1 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ATG16 PF08614.11 EAX86673.1 - 5.4e-06 26.8 2.5 5.4e-06 26.8 2.5 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EAX86673.1 - 0.0021 18.4 9.8 0.0021 18.4 9.8 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) DivIC PF04977.15 EAX86673.1 - 0.0024 17.6 8.9 2.7 7.8 0.7 3.4 3 0 0 3 3 3 3 Septum formation initiator DUF489 PF04356.12 EAX86673.1 - 0.013 15.5 8.4 0.35 10.9 0.8 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF1664 PF07889.12 EAX86673.1 - 0.051 13.6 6.1 10 6.2 0.8 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 EAX86673.1 - 0.097 12.8 9.6 0.56 10.4 9.1 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 MPS2 PF17060.5 EAX86673.1 - 0.35 10.1 9.6 0.043 13.1 3.1 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF1192 PF06698.11 EAX86673.1 - 0.58 10.3 5.6 13 5.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) KxDL PF10241.9 EAX86673.1 - 0.87 9.9 6.5 0.23 11.7 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF16 PF01519.16 EAX86673.1 - 0.98 9.9 10.7 4.8 7.7 0.0 3.6 1 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4201 PF13870.6 EAX86673.1 - 1.7 8.3 12.4 0.38 10.5 6.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 EAX86673.1 - 2 8.6 12.3 0.34 11.1 4.7 3.0 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EAX86673.1 - 2.2 8.7 12.8 10 6.5 5.6 2.7 1 1 0 2 2 2 0 Fez1 Sec8_exocyst PF04048.14 EAX86673.1 - 2.5 8.0 8.5 7.2 6.5 0.2 3.2 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain ADIP PF11559.8 EAX86673.1 - 3.7 7.6 14.8 5.9 7.0 0.8 3.8 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 EAX86673.1 - 4.9 7.4 14.6 0.31 11.3 0.4 4.0 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 EAX86673.1 - 5.8 7.6 10.2 20 5.9 0.5 3.8 3 1 1 4 4 4 0 SlyX bZIP_1 PF00170.21 EAX86673.1 - 8.2 6.6 9.9 3.6 7.8 1.5 3.3 3 0 0 3 3 3 0 bZIP transcription factor Laminin_II PF06009.12 EAX86673.1 - 9.7 6.2 9.3 3.3 7.7 3.1 2.6 3 1 0 3 3 2 0 Laminin Domain II Ras PF00071.22 EAX86674.1 - 5.5e-57 191.9 0.1 6.6e-57 191.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86674.1 - 1.2e-32 112.7 0.0 2.3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86674.1 - 5.7e-15 55.2 0.0 7.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX86674.1 - 4.8e-06 26.2 0.1 1.4e-05 24.7 0.1 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX86674.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX86674.1 - 0.00023 20.6 0.0 0.00031 20.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX86674.1 - 0.0043 17.0 0.1 3.1 7.7 0.0 2.5 1 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 EAX86674.1 - 0.0053 16.3 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SLC12 PF03522.15 EAX86676.1 - 1.6e-27 96.6 0.1 2.7e-13 49.8 0.0 3.1 1 1 2 3 3 3 3 Solute carrier family 12 AA_permease PF00324.21 EAX86676.1 - 8.6e-16 57.6 39.1 2.3e-15 56.2 39.1 1.6 1 1 0 1 1 1 1 Amino acid permease PSP PF04046.16 EAX86677.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86678.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat MBOAT PF03062.19 EAX86679.1 - 1.7e-20 73.7 12.6 1.7e-20 73.7 12.6 1.5 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DNA_pol_B_2 PF03175.13 EAX86680.1 - 8.8e-31 107.3 12.1 4.5e-30 104.9 12.1 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX86680.1 - 0.12 12.4 0.1 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor PTR PF12789.7 EAX86681.1 - 2.7e-12 46.5 43.5 2.7e-08 33.7 5.2 7.1 7 1 0 7 7 7 4 Phage tail repeat like Collagen PF01391.18 EAX86681.1 - 0.0072 16.1 5.6 0.0072 16.1 5.6 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX86681.1 - 0.015 15.4 6.3 0.035 14.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus LIFR_D2 PF17971.1 EAX86681.1 - 0.027 14.6 0.3 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain RecG_N PF17190.4 EAX86681.1 - 0.53 11.0 6.4 47 4.8 0.0 4.5 5 0 0 5 5 5 0 RecG N-terminal helical domain NPV_P10 PF05531.12 EAX86681.1 - 6.1 7.4 7.1 54 4.4 0.2 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Pox_A32 PF04665.12 EAX86682.1 - 5.4e-07 29.3 2.2 5.4e-07 29.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX86682.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86682.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX86682.1 - 0.00015 21.9 3.2 0.00031 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86682.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86682.1 - 0.0016 18.3 0.6 0.004 17.0 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX86682.1 - 0.002 17.8 0.5 0.013 15.2 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX86682.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX86682.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX86682.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86682.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX86682.1 - 0.39 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX86683.1 - 9.4e-45 151.1 0.2 2.2e-44 149.9 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86683.1 - 0.028 15.0 0.0 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX86684.1 - 4.8e-155 514.1 13.2 6e-155 513.8 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX86684.1 - 0.067 13.0 0.9 0.21 11.5 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX86685.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86686.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP GPS2_interact PF15784.5 EAX86687.1 - 0.022 15.2 1.1 0.029 14.8 1.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 EAX86688.1 - 1.3e-25 89.3 0.5 1.7e-12 47.3 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86688.1 - 1.3e-17 63.8 5.9 5.5e-13 49.0 1.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX86688.1 - 0.0065 16.5 4.4 0.015 15.3 1.9 2.4 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAX86688.1 - 0.023 14.6 5.7 0.051 13.5 0.3 2.5 1 1 0 2 2 2 0 Myb DNA-binding like Mem_trans PF03547.18 EAX86689.1 - 4.7e-23 81.2 27.0 2.8e-17 62.2 10.2 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF3989 PF13150.6 EAX86689.1 - 0.021 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Meiosis_expr PF15163.6 EAX86690.1 - 0.065 13.9 0.8 0.1 13.3 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX86690.1 - 0.17 11.7 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated RRM_1 PF00076.22 EAX86692.1 - 1.4e-11 44.1 0.1 2e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX86692.1 - 0.00042 20.2 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAX86692.1 - 0.091 12.9 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 RNA recognition motif IQ PF00612.27 EAX86693.1 - 0.058 13.2 4.1 0.28 11.1 4.1 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pox_A32 PF04665.12 EAX86695.1 - 0.00022 20.8 4.5 0.00038 20.0 4.5 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86695.1 - 0.0037 17.3 0.8 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX86695.1 - 0.011 15.3 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX86695.1 - 0.052 13.8 1.1 0.15 12.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Gly-zipper_Omp PF13488.6 EAX86696.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper ActA PF05058.12 EAX86696.1 - 0.14 10.5 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX86696.1 - 0.52 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MSC PF09402.10 EAX86697.1 - 7.4e-10 38.8 6.8 3.7e-09 36.5 6.8 1.8 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain ATG27 PF09451.10 EAX86697.1 - 0.072 12.9 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 Viral_Beta_CD PF04530.12 EAX86697.1 - 0.089 13.1 0.5 1.5 9.1 0.3 2.4 2 0 0 2 2 2 0 Viral Beta C/D like family Vps53_N PF04100.12 EAX86698.1 - 4.5e-61 206.9 3.9 1.1e-60 205.6 3.9 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal COG7 PF10191.9 EAX86698.1 - 2.8e-05 22.6 0.7 0.0021 16.4 0.0 3.0 3 0 0 3 3 3 1 Golgi complex component 7 (COG7) YnfE PF17452.2 EAX86698.1 - 0.0096 16.2 2.7 0.04 14.2 0.2 3.2 3 0 0 3 3 3 1 Uncharacterized YnfE-like Occludin_ELL PF07303.13 EAX86698.1 - 0.017 15.8 5.2 2.7 8.8 0.3 4.4 4 0 0 4 4 4 0 Occludin homology domain FliS PF02561.14 EAX86698.1 - 0.12 12.7 1.8 0.46 10.8 0.2 2.7 2 0 0 2 2 2 0 Flagellar protein FliS Peroxin-22 PF12827.7 EAX86698.1 - 0.21 11.5 2.0 1.6 8.6 1.2 2.5 1 1 1 2 2 2 0 Peroxisomal biogenesis protein family Ank_2 PF12796.7 EAX86699.1 - 5.8e-32 110.1 0.0 5.5e-14 52.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86699.1 - 1.8e-22 79.4 0.0 1.3e-07 32.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX86699.1 - 5.2e-22 77.3 0.0 9.2e-06 25.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX86699.1 - 1.5e-20 71.1 0.0 0.0004 20.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX86699.1 - 8.9e-19 67.3 0.1 9.9e-08 32.1 0.0 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) L_protein_N PF15518.6 EAX86699.1 - 0.0017 18.2 0.1 7.1 6.5 0.0 3.8 2 1 2 4 4 4 2 L protein N-terminus Ig_3 PF13927.6 EAX86702.1 - 0.00061 20.3 2.5 12 6.5 0.0 5.1 6 0 0 6 6 6 1 Immunoglobulin domain Big_3_5 PF16640.5 EAX86702.1 - 0.016 15.3 4.2 0.71 10.1 0.0 4.5 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) SH3_2 PF07653.17 EAX86702.1 - 0.021 14.5 0.0 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Variant SH3 domain tRNA_anti-codon PF01336.25 EAX86702.1 - 0.029 14.3 0.7 14 5.7 0.0 4.0 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain DUF4108 PF13390.6 EAX86703.1 - 2.9e-49 166.7 4.7 3.2e-49 166.6 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX86704.1 - 0.028 14.3 2.1 0.038 13.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PAS_2 PF08446.11 EAX86705.1 - 0.023 15.3 0.0 0.092 13.4 0.0 2.0 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 EAX86705.1 - 0.07 13.4 0.1 0.07 13.4 0.1 2.5 2 0 0 2 2 2 0 PAS domain ComA PF02679.15 EAX86706.1 - 9.6e-05 22.0 0.5 0.0013 18.2 0.1 2.0 1 1 1 2 2 2 1 (2R)-phospho-3-sulfolactate synthase (ComA) GTSE1_N PF15259.6 EAX86706.1 - 0.026 14.7 0.1 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 YGGT PF02325.17 EAX86707.1 - 0.00088 19.6 0.2 0.017 15.5 0.2 2.5 1 1 0 1 1 1 1 YGGT family PTR PF12789.7 EAX86708.1 - 3.3e-08 33.4 0.8 3.3e-08 33.4 0.8 3.1 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX86708.1 - 0.061 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Phage_TTP_12 PF16461.5 EAX86708.1 - 0.11 12.2 2.5 0.21 11.3 1.4 2.0 2 1 1 3 3 3 0 Lambda phage tail tube protein, TTP DUF3417 PF11897.8 EAX86708.1 - 0.17 12.4 1.8 0.37 11.3 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) Stathmin PF00836.19 EAX86708.1 - 3.1 7.8 9.3 0.59 10.1 3.4 2.1 2 0 0 2 2 2 0 Stathmin family DUF4107 PF13389.6 EAX86710.1 - 3e-71 238.8 2.8 3.9e-71 238.5 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX86711.1 - 7.1e-153 507.0 13.8 8.9e-153 506.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86711.1 - 0.16 12.5 2.8 2.6 8.6 0.2 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2547 PF10818.8 EAX86711.1 - 0.21 12.5 0.7 5.6 8.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Tup_N PF08581.10 EAX86711.1 - 0.35 11.2 3.6 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX86712.1 - 0.00015 22.2 0.1 0.0004 20.9 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX86712.1 - 0.01 15.6 0.1 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX86712.1 - 0.014 14.9 0.6 0.16 11.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain GPS2_interact PF15784.5 EAX86714.1 - 0.028 14.8 0.7 0.039 14.4 0.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86714.1 - 0.16 11.0 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX86715.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86716.1 - 0.078 12.9 0.6 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX86717.1 - 3.9e-72 241.7 3.6 5.1e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) LRR_5 PF13306.6 EAX86719.1 - 2.8e-54 182.5 65.0 5.1e-18 65.3 18.3 5.6 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX86719.1 - 4.7e-16 58.3 10.1 0.03 14.1 0.2 7.1 5 2 2 7 7 7 6 Leucine rich repeat PTR PF12789.7 EAX86720.1 - 2.6e-25 88.2 22.0 1.5e-22 79.4 8.3 4.7 3 1 1 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX86720.1 - 0.0086 16.6 15.4 0.72 10.4 1.4 4.0 3 1 0 4 4 4 2 YmaF family DUF4795 PF16043.5 EAX86720.1 - 0.26 10.9 10.2 2 8.0 4.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX86721.1 - 6.2e-145 481.0 10.6 7.8e-145 480.6 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX86721.1 - 0.069 13.6 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX86721.1 - 0.25 11.8 5.1 2 8.9 0.4 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86721.1 - 1.9 8.8 5.9 13 6.1 0.0 3.6 4 1 0 4 4 4 0 Tup N-terminal Rhodanese PF00581.20 EAX86722.1 - 1.1e-10 41.9 0.0 1.9e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Actin PF00022.19 EAX86723.1 - 3.2e-45 154.5 0.0 2.4e-42 145.0 0.0 2.0 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 EAX86723.1 - 0.0019 17.3 0.0 0.077 12.0 0.0 2.1 1 1 1 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 EAX86723.1 - 0.0026 16.6 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein CH PF00307.31 EAX86724.1 - 1.2e-09 38.4 0.3 1.2e-09 38.4 0.3 2.4 3 0 0 3 3 3 1 Calponin homology (CH) domain Cornifin PF02389.15 EAX86724.1 - 1.2e-06 28.8 23.0 0.00094 19.4 2.2 3.2 1 1 2 3 3 3 2 Cornifin (SPRR) family Myb_DNA-binding PF00249.31 EAX86725.1 - 3.9e-27 94.2 0.7 2.2e-14 53.4 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86725.1 - 5.9e-26 90.5 1.3 2.6e-13 50.0 1.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX86725.1 - 8.3e-08 32.0 0.6 5e-05 23.1 0.2 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX86725.1 - 2.6e-05 24.3 0.1 5.7e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX86725.1 - 0.0048 16.9 0.7 6.8 6.8 0.0 3.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX86725.1 - 0.021 15.0 0.3 2.1 8.6 0.0 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX86725.1 - 0.021 15.2 3.5 4.3 7.8 0.0 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EAX86725.1 - 0.036 14.1 0.3 0.036 14.1 0.3 1.7 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 EAX86725.1 - 0.085 13.0 0.1 0.87 9.7 0.2 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) WIYLD PF10440.9 EAX86725.1 - 0.13 12.1 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain ACP_PD PF04336.12 EAX86726.1 - 0.13 12.7 0.1 0.35 11.3 0.0 1.8 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase Ank_2 PF12796.7 EAX86728.1 - 3.5e-05 24.3 0.3 0.0087 16.6 0.3 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX86728.1 - 0.00012 22.0 0.5 0.00049 20.0 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX86728.1 - 0.00067 20.2 0.4 6.4 7.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86728.1 - 0.0031 17.9 0.0 6.2 7.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat GPS2_interact PF15784.5 EAX86729.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86729.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX86730.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX86730.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX86731.1 - 6.1e-80 268.2 9.7 8.1e-80 267.8 9.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX86731.1 - 0.084 13.2 0.8 0.26 11.6 0.1 2.2 3 0 0 3 3 3 0 PRD domain DUF2408 PF10303.9 EAX86731.1 - 0.11 13.0 0.4 0.19 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) GalP_UDP_transf PF01087.22 EAX86731.1 - 0.11 12.9 2.1 0.91 9.9 0.8 2.1 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain T5orf172 PF10544.9 EAX86732.1 - 1.2e-06 29.0 0.3 4.1e-06 27.3 0.2 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX86732.1 - 0.0012 18.4 0.3 0.016 14.7 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX86733.1 - 2.3e-32 111.1 0.4 5.9e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX86733.1 - 0.035 14.7 0.0 0.096 13.3 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Ycf34 PF10718.9 EAX86733.1 - 0.27 11.9 1.5 11 6.8 0.3 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX86734.1 - 8.5e-05 22.1 3.6 8.5e-05 22.1 3.6 1.5 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86734.1 - 0.0031 17.5 1.0 0.006 16.6 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX86734.1 - 0.015 14.9 0.2 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX86734.1 - 0.057 13.7 1.2 0.16 12.2 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX86734.1 - 0.058 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ank_2 PF12796.7 EAX86736.1 - 1.4e-19 70.4 5.7 1.8e-10 41.3 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX86736.1 - 6.3e-13 47.6 6.7 0.44 11.3 0.1 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX86736.1 - 3.5e-11 43.1 1.8 0.43 10.9 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX86736.1 - 4.6e-10 39.8 5.2 0.0023 18.4 0.2 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX86736.1 - 0.004 17.5 3.3 16 6.2 0.0 5.2 4 0 0 4 4 4 1 Ankyrin repeat SWI-SNF_Ssr4 PF08549.10 EAX86736.1 - 2 6.9 21.1 2.7 6.5 21.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) phiKZ_IP PF12699.7 EAX86737.1 - 0.25 10.4 2.9 1.4 8.0 0.8 2.3 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins AAA_22 PF13401.6 EAX86739.1 - 1.6e-05 25.2 0.1 0.00012 22.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX86739.1 - 0.00011 22.2 3.2 0.0002 21.4 3.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX86739.1 - 0.00051 19.9 0.0 0.00072 19.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX86739.1 - 0.0012 18.7 0.9 0.0037 17.1 0.9 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX86739.1 - 0.002 17.9 0.2 0.26 11.0 0.0 2.7 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX86739.1 - 0.0091 16.3 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX86739.1 - 0.056 12.9 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX86739.1 - 0.091 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX86739.1 - 0.13 12.6 0.1 0.48 10.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX86739.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX86739.1 - 0.24 11.7 4.2 6.2 7.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX86741.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2362 PF10154.9 EAX86742.1 - 0.0012 17.9 2.6 0.0017 17.4 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) EF-hand_1 PF00036.32 EAX86743.1 - 3.6e-13 48.0 3.6 9.8e-05 21.6 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EAX86743.1 - 1.7e-12 47.6 4.0 3.5e-09 37.0 0.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX86743.1 - 2.1e-12 45.9 1.4 5.5e-05 22.8 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EAX86743.1 - 1.3e-08 33.9 0.2 0.00069 19.0 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EAX86743.1 - 4.5e-08 32.8 4.9 0.068 13.0 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EAX86743.1 - 0.0069 16.7 0.2 0.13 12.6 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain Metallophos PF00149.28 EAX86745.1 - 0.047 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase pEK499_p136 PF18736.1 EAX86745.1 - 0.71 9.5 5.4 0.93 9.1 0.7 2.4 1 1 1 2 2 2 0 HEPN pEK499 p136 Metallophos PF00149.28 EAX86746.1 - 0.037 14.5 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Wzy_C PF04932.15 EAX86746.1 - 0.065 12.9 0.1 0.076 12.6 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF1736 PF08409.11 EAX86746.1 - 0.22 11.5 3.2 11 6.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1736) DUF1985 PF09331.11 EAX86747.1 - 0.029 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) Proton_antipo_N PF00662.20 EAX86747.1 - 0.15 12.1 0.4 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus dNK PF01712.19 EAX86748.1 - 1.2e-21 77.6 4.2 7.6e-19 68.4 4.2 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EAX86748.1 - 5.4e-12 46.4 0.2 1.6e-10 41.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EAX86748.1 - 3.4e-06 27.3 0.9 0.12 12.5 0.1 2.7 1 1 2 3 3 3 2 Shikimate kinase AAA_33 PF13671.6 EAX86748.1 - 1.5e-05 25.2 0.0 0.078 13.1 0.0 2.2 2 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 EAX86748.1 - 0.00029 20.6 0.8 0.062 13.0 0.2 2.5 2 1 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.6 EAX86748.1 - 0.00039 20.7 0.0 0.00074 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAX86748.1 - 0.00046 20.5 0.0 0.0008 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAX86748.1 - 0.00052 20.0 0.1 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 EAX86748.1 - 0.00055 20.5 0.2 0.0013 19.3 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 EAX86748.1 - 0.00057 20.3 0.4 0.0061 17.0 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EAX86748.1 - 0.00082 19.4 0.8 0.0011 19.0 0.2 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EAX86748.1 - 0.0013 18.5 0.2 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase WES_acyltransf PF03007.16 EAX86748.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AAA_14 PF13173.6 EAX86748.1 - 0.0026 17.8 0.7 0.0075 16.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAX86748.1 - 0.0035 17.8 0.0 0.0059 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EAX86748.1 - 0.0041 17.5 0.3 0.019 15.3 0.1 2.1 1 1 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 EAX86748.1 - 0.0048 16.8 0.4 0.028 14.3 0.1 2.3 2 1 0 2 2 2 1 NTPase TsaE PF02367.17 EAX86748.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EAX86748.1 - 0.0062 17.0 0.3 0.28 11.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EAX86748.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.18 EAX86748.1 - 0.011 15.4 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EAX86748.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 EAX86748.1 - 0.016 15.3 1.1 0.34 11.0 0.1 2.3 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.6 EAX86748.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAX86748.1 - 0.026 13.6 0.1 0.051 12.6 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Guanylate_kin PF00625.21 EAX86748.1 - 0.029 14.0 0.3 6 6.5 0.0 2.6 2 1 0 2 2 2 0 Guanylate kinase NACHT PF05729.12 EAX86748.1 - 0.043 13.7 0.0 0.079 12.9 0.0 1.6 1 1 0 1 1 1 0 NACHT domain CoaE PF01121.20 EAX86748.1 - 0.055 13.1 0.2 0.13 12.0 0.1 1.9 2 1 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.12 EAX86748.1 - 0.056 12.7 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EAX86748.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EAX86748.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EAX86748.1 - 0.12 12.8 2.5 0.28 11.7 2.5 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAX86748.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LRR_5 PF13306.6 EAX86749.1 - 1.7e-49 167.0 53.6 1e-23 83.7 19.2 4.2 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX86749.1 - 7e-12 44.9 20.5 5e-06 26.2 0.4 8.6 5 2 4 9 9 9 6 Leucine rich repeat Acetyltransf_19 PF18015.1 EAX86749.1 - 0.098 12.9 3.9 9 6.5 0.1 3.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain LRR_5 PF13306.6 EAX86750.1 - 2.1e-59 199.1 59.0 4.7e-17 62.2 6.0 6.1 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX86750.1 - 1.4e-06 27.9 8.6 6.8 6.5 0.0 8.0 5 3 3 8 8 8 3 Leucine rich repeat LRR_4 PF12799.7 EAX86750.1 - 0.01 16.3 8.3 5.6 7.5 0.0 5.7 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) PSP PF04046.16 EAX86751.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86752.1 - 0.064 13.8 4.9 13 7.0 0.2 3.4 3 1 0 3 3 3 0 TMP repeat SSP160 PF06933.11 EAX86753.1 - 7.7 4.6 18.5 7.9 4.5 18.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LRR_4 PF12799.7 EAX86755.1 - 4e-08 33.4 6.0 3.5e-05 24.1 1.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX86755.1 - 2.5e-07 30.4 0.2 4.2e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAX86755.1 - 3.9e-05 23.3 1.0 0.0001 22.0 1.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 EAX86755.1 - 0.12 12.5 1.2 0.36 11.0 0.2 2.2 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 EAX86755.1 - 0.27 11.9 2.5 10 7.1 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 EAX86756.1 - 2e-26 92.9 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86756.1 - 3.3e-14 52.8 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX86756.1 - 0.00012 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX86756.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX86756.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 EAX86756.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAX86756.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 EAX86757.1 - 8e-52 175.1 0.3 1e-51 174.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86757.1 - 5.6e-33 113.7 0.2 7.9e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86757.1 - 1e-11 44.6 0.1 1.3e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX86757.1 - 4.7e-09 36.0 0.1 5.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX86757.1 - 2.1e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX86757.1 - 6.1e-07 29.2 0.2 6.2e-06 25.9 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX86757.1 - 4.1e-05 23.6 0.5 0.032 14.1 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX86757.1 - 0.00015 21.2 0.1 0.00025 20.5 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAX86757.1 - 0.00067 19.2 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 EAX86757.1 - 0.00095 18.9 0.2 0.0019 18.0 0.2 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX86757.1 - 0.0025 17.2 0.2 0.0047 16.2 0.1 1.5 1 1 0 1 1 1 1 Septin FeoB_N PF02421.18 EAX86757.1 - 0.0033 17.0 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 EAX86757.1 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 EAX86757.1 - 0.026 14.9 0.0 0.034 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EAX86757.1 - 0.029 14.4 0.4 0.22 11.6 0.1 2.2 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 EAX86757.1 - 0.034 14.4 0.0 2 8.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX86757.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EAX86757.1 - 0.043 13.2 0.2 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 KaiC G-alpha PF00503.20 EAX86757.1 - 0.071 12.3 2.1 1.5 7.9 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 EAX86757.1 - 0.11 13.0 0.1 0.16 12.5 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EAX86757.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EAX86757.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PglD_N PF17836.1 EAX86758.1 - 0.14 12.8 0.1 0.99 10.1 0.0 2.4 3 0 0 3 3 3 0 PglD N-terminal domain Glyco_hydro_47 PF01532.20 EAX86759.1 - 6.6e-43 147.2 0.0 8.5e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DDE_Tnp_ISL3 PF01610.17 EAX86760.1 - 4e-05 23.5 0.2 0.00011 22.1 0.2 1.7 1 0 0 1 1 1 1 Transposase ubiquitin PF00240.23 EAX86763.1 - 3.3e-20 71.6 0.6 9.3e-13 47.7 0.3 2.7 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX86763.1 - 5e-16 58.3 0.2 3.4e-07 30.0 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX86763.1 - 0.00033 21.1 0.4 0.0011 19.3 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX86763.1 - 0.0019 18.1 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX86763.1 - 0.12 12.8 0.6 1.8 9.0 0.0 2.9 3 1 0 3 3 3 0 Ubiquitin-like domain ThiF PF00899.21 EAX86764.1 - 6e-71 238.7 0.5 1.2e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_FCCH PF16190.5 EAX86764.1 - 1e-23 83.3 0.8 2.1e-23 82.3 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EAX86764.1 - 0.0017 18.5 0.1 0.067 13.4 0.1 2.7 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle UBA_e1_thiolCys PF10585.9 EAX86765.1 - 3.2e-57 194.3 0.5 4.2e-57 194.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 EAX86765.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Ank_2 PF12796.7 EAX86766.1 - 7e-09 36.2 0.0 1.1e-08 35.5 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86766.1 - 1.3e-07 32.0 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86766.1 - 3.2e-07 30.5 0.0 6.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86766.1 - 1.2e-05 25.2 0.0 0.0039 17.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAX86766.1 - 0.00036 20.8 0.0 0.094 13.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Tubulin PF00091.25 EAX86767.1 - 2.4e-65 220.5 0.0 2.9e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EAX86767.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAX86767.1 - 0.21 11.3 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 Tubulin domain DUF3839 PF12943.7 EAX86768.1 - 4e-153 507.8 13.9 5.1e-153 507.5 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86768.1 - 0.094 13.2 2.5 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX86768.1 - 0.33 11.3 3.3 14 6.1 0.0 3.3 4 0 0 4 4 4 0 Tup N-terminal DDR PF08841.10 EAX86769.1 - 0.18 10.8 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1397 PF07165.11 EAX86770.1 - 0.077 12.4 0.2 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) MULE PF10551.9 EAX86771.1 - 1.7e-12 47.6 0.1 3.5e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX86771.1 - 0.15 11.7 4.6 0.23 11.1 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX86771.1 - 0.48 10.7 5.6 1.4 9.2 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX86771.1 - 1.2 8.9 5.3 1.9 8.2 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PSP PF04046.16 EAX86772.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX86774.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX86774.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX86774.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX86774.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX86774.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX86774.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX86774.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX86775.1 - 4.2e-80 268.7 9.9 5.3e-80 268.4 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86775.1 - 0.07 13.7 0.3 0.12 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX86775.1 - 0.12 11.8 0.0 0.78 9.2 0.0 2.1 1 1 1 2 2 2 0 SLOG cluster2 DUF3839 PF12943.7 EAX86776.1 - 3e-36 125.1 0.5 3.3e-36 125.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3781 PF12636.7 EAX86777.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Ank_2 PF12796.7 EAX86778.1 - 3.4e-38 130.1 20.8 1.4e-13 51.2 1.0 5.0 1 1 5 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX86778.1 - 9.8e-34 114.3 13.0 1.1e-07 31.9 0.1 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX86778.1 - 1.4e-33 114.8 11.4 1.1e-10 41.8 0.0 7.2 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86778.1 - 3.3e-29 100.6 7.5 1.8e-10 40.8 0.2 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86778.1 - 6.4e-27 90.6 14.3 0.00083 19.6 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 EAX86778.1 - 1.2e-24 86.0 7.2 1.2e-24 86.0 7.2 4.9 3 2 1 5 5 5 1 Domain of unknown function (DUF3447) CheD PF03975.13 EAX86778.1 - 0.078 13.1 0.2 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 CheD chemotactic sensory transduction PTR PF12789.7 EAX86779.1 - 6e-52 173.6 37.3 9e-30 102.5 11.4 4.3 3 1 2 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX86779.1 - 0.086 12.6 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX86779.1 - 0.73 9.4 19.7 0.065 12.8 10.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) BRO1 PF03097.18 EAX86780.1 - 0.11 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 BRO1-like domain DUF3839 PF12943.7 EAX86781.1 - 1.6e-71 240.6 2.5 1.8e-71 240.4 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX86781.1 - 0.061 13.3 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc binding domain DUF4108 PF13390.6 EAX86783.1 - 6e-65 217.5 6.2 6.7e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX86783.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3839 PF12943.7 EAX86784.1 - 4.6e-156 517.4 13.6 5.8e-156 517.1 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86784.1 - 1 9.9 8.1 3.3 8.2 1.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86784.1 - 2.4 8.7 7.1 0.87 10.2 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX86785.1 - 1.9e-23 82.3 53.5 1.2e-08 34.8 4.0 7.0 8 0 0 8 8 8 4 Phage tail repeat like Collagen PF01391.18 EAX86785.1 - 3.5e-07 29.9 14.9 5.6e-07 29.2 14.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX86785.1 - 0.011 15.9 14.6 0.04 14.0 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus EpuA PF11772.8 EAX86785.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta EMP24_GP25L PF01105.24 EAX86785.1 - 5.1 7.0 18.6 12 5.8 1.6 5.0 4 1 1 5 5 5 0 emp24/gp25L/p24 family/GOLD RraB PF06877.11 EAX86785.1 - 9 7.1 7.5 78 4.1 1.5 3.5 2 1 1 3 3 3 0 Regulator of ribonuclease activity B Amidase02_C PF12123.8 EAX86786.1 - 0.006 16.3 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86787.1 - 2.4e-71 239.1 3.8 3.2e-71 238.7 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX86788.1 - 0.16 12.0 0.0 4.5 7.3 0.0 2.1 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Gly_rich PF12810.7 EAX86789.1 - 4.3e-16 59.6 27.7 5.4e-16 59.2 27.7 1.1 1 0 0 1 1 1 1 Glycine rich protein AbiJ_NTD4 PF18863.1 EAX86790.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX86790.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein Calreticulin PF00262.18 EAX86791.1 - 2.1e-146 487.5 10.1 2.1e-146 487.5 10.1 1.8 2 0 0 2 2 1 1 Calreticulin family DUF4446 PF14584.6 EAX86791.1 - 0.021 14.8 0.3 0.037 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM176 PF14851.6 EAX86791.1 - 0.024 14.3 0.9 0.024 14.3 0.9 1.9 2 0 0 2 2 2 0 FAM176 family O-antigen_lig PF13425.6 EAX86791.1 - 0.031 13.1 2.8 0.045 12.6 2.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DNA_pol_phi PF04931.13 EAX86791.1 - 0.056 11.5 4.3 0.081 11.0 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EAX86791.1 - 0.088 12.0 1.8 0.16 11.1 1.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoside_tran PF01733.18 EAX86791.1 - 0.1 11.9 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 Nucleoside transporter SID-1_RNA_chan PF13965.6 EAX86791.1 - 0.13 10.6 0.4 0.18 10.2 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Eapp_C PF10238.9 EAX86791.1 - 0.15 12.1 3.2 0.53 10.4 0.9 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein FHIPEP PF00771.20 EAX86791.1 - 0.22 9.9 0.0 0.8 8.1 0.0 1.7 2 0 0 2 2 2 0 FHIPEP family Connexin PF00029.19 EAX86791.1 - 0.25 11.1 3.1 0.16 11.7 0.8 1.7 2 0 0 2 2 2 0 Connexin Vpu PF00558.19 EAX86791.1 - 0.58 10.0 2.9 1.3 8.9 2.9 1.5 1 0 0 1 1 1 0 Vpu protein OAD_gamma PF04277.13 EAX86791.1 - 1.2 9.8 2.5 2.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Protocadherin PF08374.11 EAX86791.1 - 2.8 7.9 5.2 1.8 8.5 0.4 2.1 1 1 1 2 2 2 0 Protocadherin Phage_Gp23 PF10669.9 EAX86791.1 - 3.4 8.0 11.3 0.044 14.1 3.9 1.6 2 0 0 2 2 1 0 Protein gp23 (Bacteriophage A118) ORC_WH_C PF18137.1 EAX86791.1 - 5.4 7.1 7.9 2.2 8.4 2.2 2.4 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal IBN_N PF03810.19 EAX86792.1 - 0.016 15.1 0.5 0.082 12.8 0.5 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain Pox_EPC_I2-L1 PF12575.8 EAX86792.1 - 0.02 15.1 0.9 0.12 12.6 0.2 2.7 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Desmo_N PF06771.11 EAX86792.1 - 0.11 12.9 0.6 0.79 10.1 0.3 2.8 1 1 0 1 1 1 0 Viral Desmoplakin N-terminus Ank_2 PF12796.7 EAX86793.1 - 3.9e-33 113.9 0.0 1.9e-11 44.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86793.1 - 1.8e-23 82.6 0.0 2.9e-07 30.9 0.0 4.2 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86793.1 - 9.3e-23 80.0 0.0 1.3e-06 28.5 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86793.1 - 3.1e-17 60.9 0.0 0.01 16.3 0.0 6.1 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX86793.1 - 5e-14 52.0 0.0 0.05 14.1 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeat DDR PF08841.10 EAX86794.1 - 0.15 11.1 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 EAX86796.1 - 3.3e-28 98.1 5.6 5.4e-16 59.0 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86796.1 - 4.7e-23 81.2 0.2 1.5e-12 47.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86796.1 - 5e-17 61.7 1.0 5.2e-12 45.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86796.1 - 1.3e-15 55.9 0.9 4.5e-07 29.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX86796.1 - 5.5e-13 48.7 0.2 6.4e-06 26.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat YabA PF06156.13 EAX86796.1 - 0.079 13.6 6.7 0.3 11.7 6.7 2.1 1 0 0 1 1 1 0 Initiation control protein YabA BST2 PF16716.5 EAX86796.1 - 0.49 11.0 10.8 1.2 9.7 10.8 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DPM3 PF08285.11 EAX86796.1 - 1.4 9.1 7.1 1.8 8.8 1.0 2.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HALZ PF02183.18 EAX86796.1 - 4 7.7 12.7 0.13 12.5 5.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMEM154 PF15102.6 EAX86797.1 - 1.3e-06 28.3 3.5 1.3e-06 28.3 3.5 2.5 3 0 0 3 3 2 1 TMEM154 protein family Orf78 PF06024.12 EAX86797.1 - 3e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Syndecan PF01034.20 EAX86797.1 - 0.0006 19.7 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain Chordopox_A13L PF05961.11 EAX86797.1 - 0.0019 18.4 1.5 0.0057 16.9 1.5 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF4834 PF16118.5 EAX86797.1 - 0.0038 18.2 0.8 0.0081 17.1 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) ECSCR PF15820.5 EAX86797.1 - 0.0048 16.7 1.1 0.013 15.3 1.1 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Rax2 PF12768.7 EAX86797.1 - 0.0067 15.9 0.2 0.015 14.7 0.2 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF5385 PF17359.2 EAX86797.1 - 0.0092 15.6 1.4 0.014 15.0 1.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 EAX86797.1 - 0.011 15.7 6.4 0.03 14.4 6.4 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RIFIN PF02009.16 EAX86797.1 - 0.015 15.3 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 EAX86797.1 - 0.042 14.7 0.1 0.089 13.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EAX86797.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Sigma_reg_N PF13800.6 EAX86797.1 - 0.09 13.1 4.7 0.11 12.8 1.3 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Podoplanin PF05808.11 EAX86797.1 - 0.16 12.0 3.3 0.42 10.7 3.3 1.7 1 0 0 1 1 1 0 Podoplanin TTL PF03133.15 EAX86798.1 - 8.5e-74 248.3 0.2 1.2e-73 247.8 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX86798.1 - 1.2e-10 41.1 0.1 9.6e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX86798.1 - 9.6e-07 28.3 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX86798.1 - 0.0026 17.8 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain LRR_4 PF12799.7 EAX86799.1 - 0.0091 16.4 0.0 0.33 11.4 0.0 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX86799.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat Hamartin PF04388.12 EAX86799.1 - 3.8 6.1 33.9 5.5 5.5 33.9 1.3 1 0 0 1 1 1 0 Hamartin protein DUF4108 PF13390.6 EAX86800.1 - 4.5e-63 211.4 5.0 5e-63 211.3 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX86802.1 - 2e-07 30.8 3.3 2.9e-07 30.2 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX86802.1 - 0.0031 17.2 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX86802.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX86802.1 - 0.06 13.1 0.1 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX86802.1 - 0.41 10.8 8.5 5.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) Ribosomal_S7e PF01251.18 EAX86804.1 - 5.1e-40 137.2 0.2 5.5e-40 137.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4108 PF13390.6 EAX86808.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) COPIIcoated_ERV PF07970.12 EAX86809.1 - 5.3e-52 176.8 0.0 6.8e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX86809.1 - 3e-16 59.5 0.1 5.2e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CBM_10 PF02013.16 EAX86809.1 - 0.26 11.8 3.9 0.51 10.9 3.9 1.4 1 0 0 1 1 1 0 Cellulose or protein binding domain EphA2_TM PF14575.6 EAX86811.1 - 0.014 16.3 3.8 0.03 15.2 3.8 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 7tm_7 PF08395.12 EAX86811.1 - 0.018 14.3 0.5 0.021 14.1 0.5 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Dehydrin PF00257.19 EAX86811.1 - 0.023 15.2 2.7 0.028 15.0 2.7 1.2 1 0 0 1 1 1 0 Dehydrin Corona_S2 PF01601.16 EAX86811.1 - 0.12 10.8 7.3 0.12 10.8 7.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2371 PF10177.9 EAX86811.1 - 0.15 12.3 0.3 0.31 11.2 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Adeno_E3_CR2 PF02439.15 EAX86811.1 - 0.52 10.1 18.7 1 9.2 18.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF347 PF03988.12 EAX86811.1 - 0.86 9.8 5.7 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) S1FA PF04689.13 EAX86811.1 - 2.3 8.4 4.1 3.9 7.7 4.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA PDCD2_C PF04194.13 EAX86812.1 - 2.8e-27 95.9 0.8 1.6e-26 93.4 0.2 2.4 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zinc_ribbon_2 PF13240.6 EAX86812.1 - 0.043 13.5 12.5 2.4 8.0 0.4 4.1 4 0 0 4 4 4 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EAX86812.1 - 0.048 13.6 8.0 0.54 10.3 1.1 3.6 3 1 0 3 3 3 0 PhnA Zinc-Ribbon DUF1451 PF07295.11 EAX86812.1 - 0.064 13.3 4.7 0.44 10.6 0.4 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain CpXC PF14353.6 EAX86812.1 - 0.11 12.5 7.2 13 5.9 0.2 3.6 4 0 0 4 4 4 0 CpXC protein ADK_lid PF05191.14 EAX86812.1 - 0.26 11.3 7.1 2.7 8.0 0.1 3.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 EAX86812.1 - 0.68 9.4 17.5 1.4 8.4 0.1 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-C4_Topoisom PF01396.19 EAX86812.1 - 1.4 8.8 12.9 6.3 6.7 0.2 3.5 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger TFIIS_C PF01096.18 EAX86812.1 - 1.4 8.8 15.0 4.3 7.3 0.9 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-Mss51 PF13824.6 EAX86812.1 - 1.8 8.7 5.5 4.9 7.3 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 A2L_zn_ribbon PF08792.10 EAX86812.1 - 2.6 7.9 6.1 6.6 6.6 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain DZR PF12773.7 EAX86812.1 - 3.4 7.8 11.4 0.32 11.1 1.0 3.0 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 EAX86812.1 - 7.2 6.6 9.8 5.7 7.0 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF563 PF04577.14 EAX86813.1 - 3.9e-12 46.8 0.1 1.1e-11 45.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LigD_N PF13298.6 EAX86813.1 - 0.14 12.4 0.0 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) PRKCSH_1 PF13015.6 EAX86814.1 - 0.072 12.8 2.3 0.42 10.3 2.3 2.0 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Ribosomal_L40e PF01020.17 EAX86815.1 - 1.3e-23 82.6 10.1 1.9e-23 82.1 10.1 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 EAX86815.1 - 4e-17 61.7 0.1 5.8e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX86815.1 - 6.9e-09 35.4 0.0 9.7e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GntR PF00392.21 EAX86815.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family zinc_ribbon_2 PF13240.6 EAX86815.1 - 0.99 9.2 6.4 11 5.9 4.0 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.7 EAX86816.1 - 4.4e-136 443.8 18.7 4.8e-21 75.1 0.1 8.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86816.1 - 5.6e-85 278.7 0.6 1.1e-11 45.0 0.0 9.6 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX86816.1 - 7.2e-82 266.5 1.1 1e-05 25.8 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 EAX86816.1 - 2.5e-75 247.6 2.9 5.7e-08 32.9 0.0 13.3 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86816.1 - 1.1e-71 228.2 0.2 0.0014 18.9 0.0 13.9 13 0 0 13 13 13 13 Ankyrin repeat DUF3083 PF11281.8 EAX86816.1 - 0.00021 20.8 0.0 4.5 6.5 0.0 4.5 1 1 2 4 4 4 1 Protein of unknown function (DUF3083) DBD_Tnp_Hermes PF10683.9 EAX86816.1 - 0.0044 16.7 0.0 89 2.9 0.0 5.7 3 2 4 7 7 7 0 Hermes transposase DNA-binding domain DUF4988 PF16378.5 EAX86816.1 - 0.0069 16.1 0.4 81 2.8 0.0 4.8 2 1 2 5 5 5 0 Domain of unknown function DUF2795 PF11387.8 EAX86816.1 - 0.01 16.0 7.6 4.7e+02 1.1 0.0 8.9 11 0 0 11 11 11 0 Protein of unknown function (DUF2795) BACK PF07707.15 EAX86816.1 - 0.031 14.4 0.5 0.065 13.3 0.5 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch DUF5082 PF16888.5 EAX86816.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) AGO_N PF18236.1 EAX86816.1 - 0.13 12.5 1.0 0.31 11.3 0.2 2.1 2 0 0 2 2 2 0 Argonaute N domain Phage_T7_Capsid PF05396.11 EAX86816.1 - 0.72 10.2 4.7 2.1e+02 2.2 0.0 5.1 6 0 0 6 6 6 0 Phage T7 capsid assembly protein DUF4106 PF13388.6 EAX86817.1 - 6e-270 895.4 22.8 6e-270 895.4 22.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX86818.1 - 6.5e-06 25.8 0.6 7.4e-06 25.6 0.6 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86818.1 - 0.0027 17.7 0.1 0.0054 16.8 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX86818.1 - 0.073 13.4 2.0 0.07 13.4 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3781 PF12636.7 EAX86819.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX86820.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX86820.1 - 0.1 11.0 1.1 0.14 10.6 1.1 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX86821.1 - 0.0025 17.5 0.0 0.007 16.0 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX86821.1 - 0.22 11.4 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Trypan_PARP PF05887.11 EAX86824.1 - 0.21 11.6 9.5 0.32 11.0 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX86825.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86826.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX86828.1 - 2.4e-156 518.3 14.1 3e-156 518.0 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86828.1 - 2.7 8.5 7.0 2 8.9 0.3 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX86828.1 - 3.3 8.3 5.6 1.2 9.7 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX86829.1 - 1.1e-05 25.9 0.9 0.00012 22.6 0.3 2.4 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX86829.1 - 0.069 12.7 0.6 0.88 9.0 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF4107 PF13389.6 EAX86830.1 - 1.1e-33 116.7 2.2 1.6e-33 116.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX86831.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF295 PF03478.18 EAX86832.1 - 0.047 13.3 1.9 0.08 12.5 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Tho2 PF11262.8 EAX86833.1 - 0.072 12.3 1.5 0.08 12.1 1.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX86833.1 - 0.6 10.1 6.9 0.21 11.5 2.9 2.2 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX86834.1 - 4.1e-155 514.3 13.2 5.1e-155 514.0 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX86834.1 - 0.048 14.1 1.4 0.22 11.9 0.2 2.1 2 0 0 2 2 2 0 Fez1 P4Ha_N PF08336.11 EAX86834.1 - 0.064 13.3 0.9 6.9 6.7 0.0 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KELK PF15796.5 EAX86834.1 - 0.074 13.5 5.4 1 9.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX86834.1 - 0.11 12.3 2.0 0.23 11.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX86834.1 - 0.27 11.6 3.6 13 6.2 0.1 3.6 3 2 2 5 5 5 0 Tup N-terminal Pkinase PF00069.25 EAX86835.1 - 3.8e-27 95.3 0.0 4.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86835.1 - 6e-15 55.2 0.0 7.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX86835.1 - 1.3e-09 37.3 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX86835.1 - 0.00022 20.9 0.0 0.00062 19.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EAX86835.1 - 0.0033 16.8 0.1 0.005 16.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX86835.1 - 0.028 14.3 0.0 0.51 10.2 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX86835.1 - 0.031 13.8 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4691 PF15762.5 EAX86835.1 - 0.094 12.9 1.1 0.15 12.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) AMP-binding PF00501.28 EAX86836.1 - 5.4e-98 328.3 0.0 7.1e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Gly-zipper_Omp PF13488.6 EAX86837.1 - 0.02 14.9 10.4 0.035 14.1 10.4 1.4 1 0 0 1 1 1 0 Glycine zipper PsbY PF06298.11 EAX86837.1 - 0.075 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX86837.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX86837.1 - 0.55 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Cytadhesin_P30 PF07271.11 EAX86838.1 - 0.44 10.1 19.4 0.74 9.3 19.4 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF4116 PF13475.6 EAX86839.1 - 0.0067 16.1 1.4 3.2 7.6 0.0 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF4116) Gp-FAR-1 PF05823.12 EAX86839.1 - 0.092 13.1 0.6 0.47 10.8 0.1 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ank_2 PF12796.7 EAX86840.1 - 2.3e-38 130.7 0.2 6.8e-19 68.2 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86840.1 - 3.4e-19 68.9 0.2 1.4e-07 31.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX86840.1 - 3.9e-16 58.7 0.0 1.4e-05 25.3 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX86840.1 - 9.4e-16 56.3 0.1 0.00025 21.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX86840.1 - 2.7e-13 49.9 0.1 1.5e-05 25.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF5049 PF16468.5 EAX86840.1 - 0.016 15.1 0.2 2.3 8.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) SEO_C PF14577.6 EAX86840.1 - 0.066 12.6 1.0 0.1 12.0 1.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Cnd1 PF12717.7 EAX86840.1 - 0.071 13.2 1.6 0.38 10.8 1.4 2.3 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2443 PF10398.9 EAX86840.1 - 1.3 9.1 6.1 0.23 11.5 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) Herpes_IE2_3 PF03361.14 EAX86841.1 - 0.0035 17.2 1.2 0.16 11.9 0.3 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX86841.1 - 0.0054 17.0 3.7 0.6 10.4 0.9 2.4 2 0 0 2 2 2 2 PPP5 TPR repeat region TolA_bind_tri PF16331.5 EAX86842.1 - 0.0094 16.0 5.0 0.0094 16.0 5.0 2.3 1 1 0 2 2 2 1 TolA binding protein trimerisation CLZ PF16526.5 EAX86842.1 - 0.01 16.2 5.1 0.01 16.2 5.1 1.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF349 PF03993.12 EAX86842.1 - 0.018 15.3 10.8 0.099 13.0 4.7 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Katanin_con80 PF13925.6 EAX86842.1 - 0.021 14.9 1.2 0.031 14.3 1.2 1.2 1 0 0 1 1 1 0 con80 domain of Katanin FAM76 PF16046.5 EAX86842.1 - 0.033 13.6 7.0 0.047 13.0 7.0 1.4 1 0 0 1 1 1 0 FAM76 protein Mut7-C PF01927.16 EAX86842.1 - 0.057 13.5 1.8 0.072 13.2 1.8 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain AIP3 PF03915.13 EAX86842.1 - 0.093 11.8 11.2 0.11 11.5 11.2 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 SpoOE-like PF09388.10 EAX86842.1 - 0.099 12.6 5.6 6 6.9 0.0 3.4 2 1 1 3 3 3 0 Spo0E like sporulation regulatory protein DUF1664 PF07889.12 EAX86842.1 - 0.3 11.1 4.5 0.24 11.5 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AATF-Che1 PF13339.6 EAX86842.1 - 0.65 10.7 7.4 0.16 12.7 3.9 1.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor KxDL PF10241.9 EAX86842.1 - 0.79 10.0 8.6 1.1 9.6 2.4 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein YabA PF06156.13 EAX86842.1 - 1.1 10.0 8.7 0.13 13.0 3.3 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 EAX86842.1 - 1.2 9.5 17.0 1.8 9.0 17.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RRN3 PF05327.11 EAX86842.1 - 1.5 7.3 7.2 1.6 7.2 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TBCA PF02970.16 EAX86842.1 - 3.1 8.2 18.3 1.1 9.6 11.7 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A Ku_C PF03730.14 EAX86842.1 - 3.7 8.3 10.5 1.8e+02 2.9 10.4 2.4 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm DUF3573 PF12097.8 EAX86842.1 - 6.5 5.5 6.1 4.2 6.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) RNA_pol_Rpc4 PF05132.14 EAX86843.1 - 2e-10 41.3 4.8 1.9e-09 38.1 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase III RPC4 MFS_1 PF07690.16 EAX86844.1 - 9.7e-36 123.4 43.4 2.8e-35 121.9 43.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 EAX86844.1 - 3.1 8.1 14.2 0.62 10.4 0.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) HIT PF01230.23 EAX86845.1 - 0.11 13.2 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 HIT domain PAP2_C PF14360.6 EAX86846.1 - 1.2e-18 67.4 6.7 1.2e-18 67.4 6.7 3.4 4 0 0 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EAX86846.1 - 3.5e-06 26.8 4.2 3.5e-06 26.8 4.2 2.5 2 0 0 2 2 2 1 PAP2 superfamily Trypan_PARP PF05887.11 EAX86847.1 - 0.8 9.7 9.9 0.94 9.5 9.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX86849.1 - 2.7e-72 242.2 4.9 3.3e-72 242.0 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86849.1 - 0.1 13.0 0.5 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Peptidase_C13 PF01650.18 EAX86851.1 - 1.4e-72 244.3 0.1 2.6e-72 243.4 0.1 1.3 1 1 0 1 1 1 1 Peptidase C13 family Ank_2 PF12796.7 EAX86852.1 - 6e-47 158.1 0.2 1.4e-22 80.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86852.1 - 2.4e-24 85.1 0.5 8.1e-10 38.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX86852.1 - 9.9e-22 76.4 0.0 1.2e-06 28.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX86852.1 - 1.3e-17 63.9 0.0 1.2e-08 35.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86852.1 - 4.4e-17 60.4 0.0 0.0006 20.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 EAX86853.1 - 7e-54 182.9 0.0 8.4e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86853.1 - 1.7e-19 70.2 0.0 3.8e-19 69.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX86853.1 - 4.2e-08 33.4 0.0 3.6e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX86853.1 - 5.5e-06 25.9 0.0 8.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAX86853.1 - 0.0087 15.7 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAX86853.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX86853.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_assoc2 PF16624.5 EAX86854.1 - 0.016 16.2 3.3 0.02 15.9 3.1 1.3 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger SLC12 PF03522.15 EAX86854.1 - 0.016 14.2 0.4 0.019 14.0 0.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NEMP PF10225.9 EAX86854.1 - 0.67 9.6 1.5 0.76 9.4 1.5 1.1 1 0 0 1 1 1 0 NEMP family DUF1477 PF07346.11 EAX86855.1 - 0.077 13.3 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1477) Phage_int_SAM_1 PF02899.17 EAX86856.1 - 0.00085 19.6 0.1 0.0012 19.1 0.1 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Trans_reg_C PF00486.28 EAX86856.1 - 0.025 14.6 0.0 0.05 13.7 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal GIT_CC PF16559.5 EAX86856.1 - 0.15 12.0 0.5 0.77 9.7 0.1 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ORC6 PF05460.13 EAX86857.1 - 1.7 7.9 22.4 1.9 7.7 22.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RR_TM4-6 PF06459.12 EAX86857.1 - 8 6.2 21.3 10 5.8 21.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3839 PF12943.7 EAX86859.1 - 8e-126 418.4 7.1 9e-126 418.2 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86859.1 - 0.96 9.9 4.0 1.3 9.5 1.2 2.6 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Not1 PF04054.15 EAX86861.1 - 8.6e-31 107.2 6.5 2.7e-26 92.4 3.2 3.2 1 1 1 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAX86861.1 - 1.3e-23 83.6 0.1 6.8e-23 81.2 0.1 2.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EAX86861.1 - 1.3e-14 53.8 2.2 3.7e-14 52.3 0.9 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EAX86861.1 - 0.0032 17.4 2.2 0.13 12.2 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) FANCI_S2 PF14676.6 EAX86861.1 - 0.035 14.4 1.6 0.22 11.8 0.9 2.9 2 0 0 2 2 2 0 FANCI solenoid 2 FliG_C PF01706.16 EAX86861.1 - 0.047 13.9 0.0 0.28 11.4 0.0 2.4 1 0 0 1 1 1 0 FliG C-terminal domain Tctex-1 PF03645.13 EAX86861.1 - 0.13 12.5 1.1 1.5 9.1 0.1 3.2 3 0 0 3 3 3 0 Tctex-1 family Lipase_3 PF01764.25 EAX86862.1 - 9.1e-09 35.3 0.6 2.3e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 Lipase (class 3) FSH1 PF03959.13 EAX86862.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Shisa PF13908.6 EAX86862.1 - 0.0092 16.2 0.5 0.033 14.4 0.4 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Carot_N PF09150.10 EAX86862.1 - 0.028 14.3 0.3 0.062 13.2 0.3 1.5 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Viral_Beta_CD PF04530.12 EAX86862.1 - 0.45 10.8 5.0 0.66 10.3 0.6 2.4 2 0 0 2 2 2 0 Viral Beta C/D like family Fijivirus_P9-2 PF06837.11 EAX86863.1 - 0.66 9.4 2.7 1.9 7.9 1.9 2.1 2 0 0 2 2 2 0 Fijivirus P9-2 protein DUF4957 PF16318.5 EAX86863.1 - 1.7 8.6 8.2 0.84 9.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) Ras PF00071.22 EAX86864.1 - 7.7e-24 84.1 0.0 9.9e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86864.1 - 2.2e-14 53.7 0.0 3.4e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EAX86864.1 - 0.00014 21.7 1.1 0.00017 21.5 1.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EAX86864.1 - 0.0041 17.6 0.0 0.0091 16.5 0.0 1.8 1 1 1 2 2 2 1 ABC transporter AAA_24 PF13479.6 EAX86864.1 - 0.0042 16.8 0.0 0.039 13.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAX86864.1 - 0.018 14.9 0.0 1.4 8.8 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase AAA_21 PF13304.6 EAX86864.1 - 0.038 13.8 0.4 0.15 11.8 0.4 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EAX86864.1 - 0.046 13.5 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EAX86864.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX86864.1 - 0.19 12.0 0.0 0.35 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EAX86865.1 - 2.9e-20 72.7 9.3 7e-08 33.0 0.2 3.8 2 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX86865.1 - 4.3e-16 59.0 5.1 1.2e-05 25.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX86865.1 - 3.1e-13 49.7 5.9 0.0026 18.1 0.0 6.5 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86865.1 - 7.5e-12 44.4 9.9 0.0029 18.0 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 EAX86865.1 - 0.00015 22.0 8.7 0.19 12.2 0.0 5.8 7 0 0 7 7 7 1 Ankyrin repeat DUF3798 PF12683.7 EAX86865.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Ank_3 PF13606.6 EAX86866.1 - 0.00017 21.8 0.0 0.00022 21.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EAX86866.1 - 0.00031 21.3 0.1 0.00034 21.1 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86866.1 - 0.0026 18.0 0.0 0.003 17.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX86866.1 - 0.0077 16.6 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EAX86866.1 - 0.012 16.2 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNAse_A_bac PF18431.1 EAX86866.1 - 0.14 13.1 0.0 0.16 13.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain Pkinase PF00069.25 EAX86867.1 - 7.6e-65 218.9 0.2 9.1e-65 218.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86867.1 - 6.1e-37 127.3 0.1 7.6e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX86867.1 - 9.1e-05 21.9 0.0 0.00021 20.7 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX86867.1 - 0.0088 15.0 2.3 0.047 12.6 2.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EAX86867.1 - 0.058 13.0 0.1 7.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EphA2_TM PF14575.6 EAX86868.1 - 0.04 14.8 0.1 0.083 13.8 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5383 PF17355.2 EAX86868.1 - 0.045 14.1 1.1 0.11 12.9 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Sarcoglycan_2 PF05510.13 EAX86868.1 - 0.048 12.4 2.9 13 4.4 0.5 3.1 3 0 0 3 3 3 0 Sarcoglycan alpha/epsilon DUF3377 PF11857.8 EAX86868.1 - 0.064 13.2 0.6 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3827 PF12877.7 EAX86868.1 - 0.11 10.8 1.2 0.16 10.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4448 PF14610.6 EAX86868.1 - 0.11 12.2 1.3 2.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) RCR PF12273.8 EAX86868.1 - 0.14 12.8 0.1 0.53 11.0 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 EAX86868.1 - 0.15 12.0 0.9 0.32 10.9 0.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_S49_N PF08496.10 EAX86868.1 - 0.17 11.9 0.1 0.43 10.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Insulin_TMD PF17870.1 EAX86868.1 - 0.24 11.5 4.0 0.49 10.5 4.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Hydrolase_4 PF12146.8 EAX86869.1 - 7.3e-08 32.0 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX86869.1 - 6.1e-07 29.3 0.0 4.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EAX86869.1 - 0.00018 21.2 0.2 0.082 12.4 0.2 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EAX86869.1 - 0.00045 20.9 0.0 0.00099 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAX86869.1 - 0.0074 15.8 0.0 0.027 14.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAX86869.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EAX86869.1 - 0.14 11.8 0.0 0.49 10.0 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Aminotran_1_2 PF00155.21 EAX86870.1 - 5.2e-58 197.0 0.0 5.9e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Guanylate_cyc PF00211.20 EAX86871.1 - 0.0042 16.7 0.1 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 EAX86871.1 - 0.038 14.0 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 EAX86871.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EAX86871.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold KIAA1430 PF13879.6 EAX86872.1 - 0.034 14.9 1.6 0.051 14.3 1.6 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX86873.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PTR PF12789.7 EAX86875.1 - 7.9e-31 105.9 11.8 7.9e-31 105.9 11.8 3.8 3 1 1 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX86875.1 - 0.19 11.5 0.9 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX86876.1 - 0.072 13.6 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX86877.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX86878.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX86879.1 - 1.8e-37 127.1 5.1 5.4e-37 125.6 5.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX86879.1 - 0.00057 20.4 0.3 0.022 15.3 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) AAA PF00004.29 EAX86880.1 - 9.4e-44 149.0 0.0 1.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAX86880.1 - 1.6e-10 40.6 0.0 3.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAX86880.1 - 1.2e-08 35.0 0.1 6e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAX86880.1 - 7.8e-07 29.6 0.3 5.2e-05 23.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EAX86880.1 - 5.5e-06 26.6 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAX86880.1 - 2.2e-05 24.8 1.1 0.0061 16.8 1.1 2.7 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 EAX86880.1 - 3.5e-05 23.7 0.6 0.00026 20.9 0.1 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain DUF815 PF05673.13 EAX86880.1 - 0.00016 21.0 0.0 0.00028 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EAX86880.1 - 0.00017 21.4 0.1 0.00071 19.3 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAX86880.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EAX86880.1 - 0.0008 18.7 0.1 0.0026 17.0 0.0 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EAX86880.1 - 0.00098 18.6 0.5 0.0043 16.5 0.3 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAX86880.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 EAX86880.1 - 0.0018 18.6 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX86880.1 - 0.0063 16.1 0.2 0.015 14.8 0.2 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EAX86880.1 - 0.011 15.5 0.2 0.099 12.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EAX86880.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EAX86880.1 - 0.011 15.6 0.1 0.064 13.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 EAX86880.1 - 0.011 15.1 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EAX86880.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EAX86880.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX86880.1 - 0.021 14.3 0.0 0.044 13.3 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EAX86880.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EAX86880.1 - 0.028 14.1 0.1 0.062 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EAX86880.1 - 0.029 14.4 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EAX86880.1 - 0.032 14.3 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAX86880.1 - 0.037 13.4 0.1 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 EAX86880.1 - 0.044 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein NTPase_1 PF03266.15 EAX86880.1 - 0.074 13.0 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EAX86880.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.16 EAX86880.1 - 0.087 12.2 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Isopentenyl transferase AAA_3 PF07726.11 EAX86880.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX86880.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 EAX86880.1 - 0.16 12.3 0.1 0.49 10.7 0.1 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 EAX86880.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 EAX86880.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavokinase PF01687.17 EAX86882.1 - 2e-35 121.4 0.0 2.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DUF4107 PF13389.6 EAX86886.1 - 4.8e-72 241.4 4.0 6.2e-72 241.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Histone PF00125.24 EAX86887.1 - 6.5e-50 168.9 0.9 7.2e-50 168.7 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX86887.1 - 1.2e-05 25.4 0.1 2.6e-05 24.3 0.0 1.6 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX86887.1 - 0.00037 21.1 1.1 0.00048 20.7 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX86887.1 - 0.00041 20.7 0.0 0.00067 20.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EAX86887.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EAX86887.1 - 0.2 12.0 1.2 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF6_C PF07571.13 EAX86888.1 - 0.015 15.6 0.7 0.082 13.2 0.4 2.2 1 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain XkdW PF09636.10 EAX86888.1 - 0.048 13.7 0.1 2 8.5 0.1 2.6 2 0 0 2 2 2 0 XkdW protein ACCA PF03255.14 EAX86888.1 - 2.6 7.9 6.9 1.3 8.9 1.6 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BLOC1_2 PF10046.9 EAX86888.1 - 6.6 7.1 10.2 1.2 9.5 4.0 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNase_J_C PF17770.1 EAX86888.1 - 9.8 7.3 8.7 11 7.1 0.7 3.4 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain AI-2E_transport PF01594.16 EAX86889.1 - 0.31 10.1 1.1 0.47 9.6 1.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter DEAD PF00270.29 EAX86890.1 - 1.9e-40 138.5 0.0 4.1e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX86890.1 - 3.1e-29 101.5 1.0 1.3e-25 89.9 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAX86890.1 - 9.3e-08 32.3 0.0 5.9e-07 29.6 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAX86890.1 - 0.0023 17.2 0.1 0.0048 16.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AI-2E_transport PF01594.16 EAX86892.1 - 0.22 10.7 1.1 0.32 10.1 1.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter Pkinase PF00069.25 EAX86893.1 - 8.4e-69 231.9 0.0 1.1e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86893.1 - 1.5e-37 129.3 0.0 2.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EAX86893.1 - 4.6e-15 55.6 0.6 9.9e-08 32.1 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EAX86893.1 - 1.1e-10 41.4 0.0 4.1e-09 36.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX86893.1 - 0.023 13.7 3.4 0.085 11.8 3.4 1.9 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAX86893.1 - 0.031 13.9 0.5 1.2 8.7 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Macoilin PF09726.9 EAX86894.1 - 0.19 10.3 6.9 0.28 9.7 6.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF4304 PF14137.6 EAX86894.1 - 1.2 9.3 4.6 1.7 8.8 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4304) DUF3839 PF12943.7 EAX86896.1 - 1.2e-155 516.0 13.7 1.5e-155 515.7 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX86896.1 - 0.49 10.9 6.3 1.9 9.0 0.4 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX86896.1 - 0.71 10.5 4.6 1 10.0 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX86897.1 - 1.1e-154 512.9 12.5 1.3e-154 512.7 12.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX86897.1 - 1 9.9 4.4 1.5 9.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX86897.1 - 3.8 8.0 7.3 1.6 9.2 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX86899.1 - 9.4e-73 243.7 3.9 1.2e-72 243.3 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Tetraspanin PF00335.20 EAX86900.1 - 7e-05 22.7 17.9 0.0041 16.9 17.9 2.0 1 1 0 1 1 1 1 Tetraspanin family DUF2070 PF09843.9 EAX86900.1 - 0.041 12.2 5.7 0.058 11.7 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PgaD PF13994.6 EAX86900.1 - 0.12 12.5 1.3 1.6 8.7 0.5 2.2 2 0 0 2 2 2 0 PgaD-like protein P21-Arc PF04062.14 EAX86900.1 - 0.21 11.6 0.6 6.5 6.8 0.1 2.7 3 0 0 3 3 3 0 ARP2/3 complex ARPC3 (21 kDa) subunit DUF3042 PF11240.8 EAX86900.1 - 1.2 9.3 5.3 5.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) DUF2116 PF09889.9 EAX86900.1 - 1.4 9.0 4.7 4.3 7.4 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EphA2_TM PF14575.6 EAX86900.1 - 2.2 9.2 0.0 2.2 9.2 0.0 3.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FtsX PF02687.21 EAX86900.1 - 4.8 7.7 22.6 0.091 13.2 1.1 2.8 1 1 1 2 2 2 0 FtsX-like permease family LGT PF01790.18 EAX86900.1 - 6.9 5.8 17.7 23 4.1 14.5 2.6 1 1 1 2 2 2 0 Prolipoprotein diacylglyceryl transferase DUF2407_C PF13373.6 EAX86901.1 - 2.2e-12 47.3 1.0 7.8e-11 42.3 1.0 2.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain Homeodomain PF00046.29 EAX86901.1 - 0.043 13.7 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 Homeodomain RBD PF02196.15 EAX86901.1 - 0.08 13.0 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain Rad60-SLD_2 PF13881.6 EAX86901.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LMBR1 PF04791.16 EAX86902.1 - 9.7e-33 113.8 37.4 1.9e-17 63.4 8.2 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein HSA PF07529.13 EAX86902.1 - 0.23 11.8 1.6 0.39 11.1 1.6 1.3 1 0 0 1 1 1 0 HSA TMEM132D_C PF15706.5 EAX86902.1 - 0.28 11.0 0.0 0.28 11.0 0.0 3.3 4 0 0 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MAP17 PF15807.5 EAX86902.1 - 0.46 10.7 0.0 0.46 10.7 0.0 2.6 4 0 0 4 4 4 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NrsF PF06532.11 EAX86902.1 - 7.1 6.3 8.2 3.6 7.3 5.1 2.1 2 0 0 2 2 2 0 Negative regulator of sigma F ubiquitin PF00240.23 EAX86903.1 - 8.7e-20 70.3 0.2 9.5e-20 70.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX86903.1 - 4.5e-11 42.4 0.0 4.8e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX86903.1 - 0.00065 19.6 0.1 0.00079 19.3 0.1 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX86903.1 - 0.0019 18.3 0.1 0.0067 16.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX86903.1 - 0.003 18.0 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 EAX86903.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 TUG ubiquitin-like domain ubiquitin PF00240.23 EAX86905.1 - 2.9e-28 97.4 6.5 6.8e-14 51.4 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX86905.1 - 5.1e-12 45.4 7.1 1.6e-06 27.9 0.4 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX86905.1 - 3.9e-06 27.1 3.2 0.005 17.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX86905.1 - 3.4e-05 23.7 1.0 0.0026 17.6 0.3 2.5 2 1 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain GABP-alpha PF11620.8 EAX86905.1 - 0.0028 17.8 1.7 1.7 8.9 0.2 2.3 2 0 0 2 2 2 2 GA-binding protein alpha chain DUF1967 PF09269.11 EAX86905.1 - 0.093 12.7 0.8 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Ubiquitin_2 PF14560.6 EAX86905.1 - 0.13 12.8 3.0 5.9 7.4 0.5 2.7 2 2 0 2 2 2 0 Ubiquitin-like domain PSP PF04046.16 EAX86917.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX86918.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX86918.1 - 0.067 13.8 4.9 12 7.1 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX86920.1 - 1.6e-37 129.5 15.2 6.7e-37 127.4 15.2 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX86920.1 - 0.077 13.3 0.1 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) JMY PF15871.5 EAX86920.1 - 0.091 12.0 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Lac_bphage_repr PF06543.12 EAX86920.1 - 0.15 12.0 0.1 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor T5orf172 PF10544.9 EAX86921.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX86922.1 - 1.6e-155 515.7 13.3 2e-155 515.3 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) L27_1 PF09058.10 EAX86923.1 - 0.0098 15.8 3.3 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 L27_1 CREPT PF16566.5 EAX86923.1 - 0.042 14.0 0.9 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX86923.1 - 0.089 12.8 0.8 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX86923.1 - 3.8 7.7 9.5 0.47 10.6 1.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PRA-PH PF01503.17 EAX86924.1 - 0.21 12.1 1.8 2 8.9 2.8 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Myb_DNA-binding PF00249.31 EAX86926.1 - 2.1e-27 95.0 3.3 2.1e-14 53.5 1.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86926.1 - 7.2e-27 93.4 4.2 2.5e-17 62.8 0.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX86926.1 - 2.6e-06 27.4 0.7 0.033 14.2 0.1 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX86926.1 - 3.7e-05 23.5 0.3 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX86926.1 - 0.00022 21.4 0.4 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EAX86926.1 - 0.068 13.5 5.1 0.87 9.9 0.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 EAX86926.1 - 0.075 13.4 8.8 1.4 9.3 1.3 3.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5491 PF17595.2 EAX86926.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5491) MULE PF10551.9 EAX86927.1 - 8.5e-06 26.1 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Macoilin PF09726.9 EAX86928.1 - 2.6 6.5 17.3 2.6 6.5 17.3 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 EAX86928.1 - 6.8 3.7 15.2 8.1 3.4 15.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MULE PF10551.9 EAX86929.1 - 1.2e-10 41.7 1.0 1.9e-10 41.0 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX86929.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family UL45 PF05473.12 EAX86930.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like LAP1C PF05609.12 EAX86931.1 - 0.15 11.1 47.9 0.17 11.0 47.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MT-A70 PF05063.14 EAX86932.1 - 1e-30 106.9 0.0 1.6e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Ank_2 PF12796.7 EAX86933.1 - 5.1e-07 30.2 0.0 6.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86933.1 - 1.3e-06 28.6 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX86933.1 - 5.5e-06 26.8 0.0 6.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX86933.1 - 1.7e-05 25.0 0.0 9.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EAX86933.1 - 0.00011 22.4 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat F5_F8_type_C PF00754.25 EAX86934.1 - 0.00016 21.8 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Myb_DNA-binding PF00249.31 EAX86935.1 - 1.6e-27 95.4 0.8 3.8e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86935.1 - 8.4e-20 70.8 2.8 3.4e-09 36.8 0.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX86935.1 - 3.5e-06 26.8 1.1 0.00042 20.2 0.2 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX86935.1 - 9.6e-05 22.5 2.8 0.0012 19.0 2.5 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX86935.1 - 0.00012 22.1 4.3 0.072 13.1 0.0 3.2 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX86935.1 - 0.011 16.1 8.2 7.5 7.0 0.1 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX86935.1 - 0.014 15.6 7.0 1.3 9.2 0.1 3.3 2 1 1 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 EAX86935.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF722 PF05263.11 EAX86935.1 - 0.71 10.1 5.2 0.54 10.5 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF722) Myb_DNA-bind_5 PF13873.6 EAX86935.1 - 6.2 7.0 10.2 10 6.3 0.2 3.9 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX86936.1 - 4.2e-19 68.5 0.2 1.2e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86936.1 - 1e-16 60.9 3.6 1.2e-11 44.6 0.1 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX86936.1 - 2e-05 24.7 1.7 0.0041 17.3 1.1 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX86936.1 - 0.00062 19.6 2.9 0.012 15.5 0.3 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX86936.1 - 0.003 17.6 3.8 0.12 12.4 0.0 3.1 1 1 2 3 3 3 1 SLIDE PIN_2 PF10130.9 EAX86936.1 - 0.036 14.3 1.1 6.1 7.1 0.0 2.2 1 1 1 2 2 2 0 PIN domain Rap1_C PF11626.8 EAX86936.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF722 PF05263.11 EAX86936.1 - 0.12 12.6 3.3 0.57 10.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF722) DUF2475 PF10629.9 EAX86936.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) Pkinase_Tyr PF07714.17 EAX86937.1 - 4.8e-09 35.9 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX86937.1 - 1.9e-08 34.0 0.0 3.2e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAX86937.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Laminin_I PF06008.14 EAX86938.1 - 1.4e-05 24.9 11.1 0.009 15.8 5.9 2.3 1 1 1 2 2 2 2 Laminin Domain I KASH_CCD PF14662.6 EAX86938.1 - 0.00048 20.0 6.8 0.00048 20.0 6.8 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 EAX86938.1 - 0.0013 18.6 5.1 0.0019 18.0 5.1 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 EAX86938.1 - 0.0016 18.1 10.8 0.0024 17.5 10.8 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.11 EAX86938.1 - 0.0036 16.2 7.8 0.0073 15.2 7.7 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein GCN5L1 PF06320.13 EAX86938.1 - 0.011 15.9 4.9 0.3 11.3 1.1 2.7 1 1 3 4 4 4 0 GCN5-like protein 1 (GCN5L1) CENP-F_leu_zip PF10473.9 EAX86938.1 - 0.022 14.8 4.4 0.043 13.8 3.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3552 PF12072.8 EAX86938.1 - 0.024 14.0 4.8 1.8 7.9 2.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Sec34 PF04136.15 EAX86938.1 - 0.026 14.4 21.5 0.48 10.3 1.8 3.2 1 1 2 3 3 3 0 Sec34-like family DUF1664 PF07889.12 EAX86938.1 - 0.029 14.4 5.0 0.12 12.4 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 EAX86938.1 - 0.03 14.4 7.2 0.92 9.6 0.9 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 EAX86938.1 - 0.04 14.4 2.1 36 4.9 2.4 3.2 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EAX86938.1 - 0.051 14.2 1.5 2.5 8.8 0.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 EAX86938.1 - 0.063 13.7 10.0 0.93 10.0 0.8 3.1 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.12 EAX86938.1 - 0.064 13.3 22.2 0.085 12.9 6.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EAX86938.1 - 0.1 12.0 2.5 0.4 10.0 2.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAX86938.1 - 0.16 12.0 10.5 0.37 10.8 1.6 2.4 1 1 1 2 2 2 0 Laminin Domain II Ax_dynein_light PF10211.9 EAX86938.1 - 0.21 11.5 0.8 3.2 7.6 0.8 2.2 1 1 0 1 1 1 0 Axonemal dynein light chain DUF3450 PF11932.8 EAX86938.1 - 0.22 10.8 20.5 0.23 10.7 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AIP3 PF03915.13 EAX86938.1 - 0.34 9.9 7.7 0.42 9.6 7.7 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Tropomyosin_1 PF12718.7 EAX86938.1 - 0.56 10.4 4.1 1.5 9.0 1.6 2.2 1 1 1 2 2 2 0 Tropomyosin like APG6_N PF17675.1 EAX86938.1 - 0.67 10.5 12.3 6.9 7.2 8.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EAX86938.1 - 0.71 10.1 14.5 1.4e+02 2.6 14.5 2.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Prominin PF05478.11 EAX86938.1 - 0.75 7.7 12.1 2.2 6.1 2.9 2.0 1 1 1 2 2 2 0 Prominin DUF4201 PF13870.6 EAX86938.1 - 0.76 9.5 3.2 10 5.8 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF812 PF05667.11 EAX86938.1 - 0.94 8.3 10.1 1.2 7.9 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4618 PF15397.6 EAX86938.1 - 1.5 8.2 10.2 0.66 9.4 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CorA PF01544.18 EAX86938.1 - 2.3 7.5 11.3 1.9 7.8 4.0 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.11 EAX86938.1 - 2.6 8.6 14.7 6.3e+03 -2.2 14.7 2.8 1 1 0 1 1 0 0 Syntaxin 6, N-terminal Leu_zip PF15294.6 EAX86938.1 - 2.9 7.3 6.9 5.7 6.4 6.9 1.5 1 1 0 1 1 1 0 Leucine zipper FUSC PF04632.12 EAX86938.1 - 3.6 6.0 17.4 5.3 5.4 17.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rootletin PF15035.6 EAX86938.1 - 4.6 7.2 12.7 2.1e+02 1.8 12.7 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 EAX86938.1 - 7.9 6.7 7.4 7.5 6.7 3.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Synaptobrevin PF00957.21 EAX86938.1 - 7.9 6.4 22.8 8.8 6.2 0.6 4.6 1 1 5 6 6 6 0 Synaptobrevin Amidase02_C PF12123.8 EAX86939.1 - 0.0033 17.1 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX86940.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX86940.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Peptidase_M8 PF01457.16 EAX86944.1 - 0.00038 19.3 0.0 0.0004 19.2 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_3 PF13582.6 EAX86944.1 - 0.029 14.9 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SprT-like PF10263.9 EAX86944.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 SprT-like family FAR1 PF03101.15 EAX86945.1 - 0.021 15.5 1.3 0.061 14.0 1.3 1.7 1 1 0 1 1 1 0 FAR1 DNA-binding domain MULE PF10551.9 EAX86946.1 - 7.4e-12 45.5 0.1 1.2e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX86946.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 PWI domain RRM_1 PF00076.22 EAX86947.1 - 8.1e-28 96.1 6.4 1.5e-10 40.8 0.1 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX86947.1 - 1.7e-07 31.1 7.4 0.022 14.8 0.1 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX86947.1 - 2.4e-07 30.8 6.7 0.011 15.7 0.2 3.6 2 1 1 3 3 3 3 RNA binding motif RRM_occluded PF16842.5 EAX86947.1 - 0.00033 20.5 0.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EAX86947.1 - 0.13 12.3 1.0 32 4.7 0.1 3.4 2 2 0 2 2 2 0 RNA recognition motif DUF2960 PF11173.8 EAX86947.1 - 2.2 8.8 7.4 0.37 11.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) Pox_A32 PF04665.12 EAX86950.1 - 0.00015 21.3 2.7 0.00017 21.2 1.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86950.1 - 0.0059 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX86950.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Spo12 PF05032.12 EAX86951.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Ras PF00071.22 EAX86952.1 - 5.4e-35 120.4 0.1 6.1e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX86952.1 - 9.9e-25 87.1 0.0 1.6e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX86952.1 - 4e-10 39.4 0.1 4.6e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX86952.1 - 5.4e-10 39.0 0.1 6.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EAX86952.1 - 0.00035 19.8 2.3 0.017 14.3 0.2 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EAX86952.1 - 0.003 17.6 0.0 0.0049 17.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX86952.1 - 0.0041 17.0 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase DLIC PF05783.11 EAX86952.1 - 0.081 11.7 0.1 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 EAX86952.1 - 0.093 12.3 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B SNAP PF14938.6 EAX86953.1 - 3.1e-63 213.8 27.6 3.5e-63 213.7 27.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EAX86953.1 - 5.9e-10 39.3 12.1 2.8e-07 30.7 0.9 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EAX86953.1 - 7.5e-06 25.6 7.1 1.3e-05 24.7 7.1 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 EAX86953.1 - 1.9e-05 24.3 8.8 1.7 8.6 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX86953.1 - 0.00013 22.5 13.1 1.9 9.5 0.1 6.2 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX86953.1 - 0.00013 21.7 9.2 1.7 8.9 0.0 5.8 3 1 2 5 5 5 1 Tetratricopeptide repeat DUF1088 PF06469.11 EAX86953.1 - 0.00083 19.1 4.8 0.061 13.0 0.1 3.2 1 1 1 3 3 3 1 Domain of Unknown Function (DUF1088) TPR_6 PF13174.6 EAX86953.1 - 0.014 15.9 12.5 14 6.5 0.1 6.0 4 1 2 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAX86953.1 - 0.016 14.7 0.9 0.061 12.8 0.6 2.3 2 0 0 2 2 1 0 SHNi-TPR FAT PF02259.23 EAX86953.1 - 0.025 13.8 11.4 0.017 14.3 1.1 2.3 1 1 1 2 2 2 0 FAT domain ATP13 PF12921.7 EAX86953.1 - 0.039 13.8 1.2 4.6 7.1 0.4 3.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression TPR_2 PF07719.17 EAX86953.1 - 0.054 13.6 25.0 1.4 9.2 0.8 6.6 6 2 3 9 9 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 EAX86953.1 - 0.12 12.0 11.9 0.15 11.8 5.1 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4745 PF15923.5 EAX86953.1 - 0.13 12.3 3.6 0.14 12.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4745) Pkip-1 PF06878.11 EAX86953.1 - 0.15 12.1 6.9 0.087 12.9 1.3 3.0 1 1 1 3 3 3 0 Pkip-1 protein FRB_dom PF08771.11 EAX86953.1 - 0.16 12.4 8.5 0.93 9.9 0.2 3.9 1 1 3 4 4 4 0 FKBP12-rapamycin binding domain Clathrin PF00637.20 EAX86953.1 - 0.27 11.1 10.4 0.44 10.4 2.2 3.4 1 1 2 4 4 4 0 Region in Clathrin and VPS Vps35 PF03635.17 EAX86953.1 - 0.34 9.3 8.6 0.4 9.1 8.1 1.3 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 TPR_19 PF14559.6 EAX86953.1 - 0.42 11.1 15.4 3.1 8.4 1.1 4.7 1 1 3 4 4 4 0 Tetratricopeptide repeat NSF PF02071.20 EAX86953.1 - 0.66 11.0 22.1 8.9 7.6 0.7 8.5 7 2 4 11 11 10 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 EAX86953.1 - 1.2 9.1 20.9 1.3 9.0 0.6 5.5 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAX86953.1 - 1.4 9.6 15.0 6.1 7.6 1.4 4.5 3 2 1 4 4 3 0 Tetratricopeptide repeat AvrM_N PF18247.1 EAX86953.1 - 2.8 8.0 7.8 2 8.4 0.3 3.5 2 1 1 3 3 2 0 Flax-rust effector AvrM N-terminal domain TPR_8 PF13181.6 EAX86953.1 - 3.7 8.0 22.3 4.5 7.7 0.0 6.4 4 1 5 9 9 9 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX86954.1 - 3.3e-50 170.9 0.2 4.1e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX86954.1 - 1.6e-22 80.0 0.0 2e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX86954.1 - 5.8e-07 29.1 0.1 0.00047 19.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAX86954.1 - 4.3e-06 25.8 0.0 6.5e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX86954.1 - 0.00033 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX86954.1 - 0.00073 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IZUMO PF15005.6 EAX86954.1 - 0.0085 16.6 1.9 0.71 10.4 0.1 2.1 2 0 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated Choline_kinase PF01633.20 EAX86954.1 - 0.059 12.9 1.5 0.064 12.8 0.5 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase FGGY_C PF02782.16 EAX86954.1 - 0.073 12.8 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain CobU PF02283.16 EAX86954.1 - 0.11 12.0 0.1 0.25 10.9 0.1 1.4 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Phyto_Pns9_10 PF05878.11 EAX86954.1 - 0.16 11.1 0.8 0.29 10.3 0.8 1.5 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DNTTIP1_dimer PF18192.1 EAX86954.1 - 0.38 11.1 4.1 1 9.8 0.2 2.6 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain Cyclin_N PF00134.23 EAX86955.1 - 2.1e-22 79.2 0.3 4.6e-22 78.1 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPR_MLP1_2 PF07926.12 EAX86956.1 - 0.014 15.4 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX86956.1 - 0.06 12.5 2.0 0.07 12.3 2.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX86956.1 - 0.091 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX86956.1 - 6.9 6.7 14.3 0.4 10.6 4.4 3.1 4 0 0 4 4 4 0 Spo12 family PRP38 PF03371.15 EAX86957.1 - 5.2e-39 133.9 0.0 7.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 PRP38 family YfdX PF10938.8 EAX86958.1 - 0.014 15.4 2.5 0.014 15.4 2.5 4.4 4 1 1 5 5 5 0 YfdX protein HicB_lk_antitox PF15919.5 EAX86958.1 - 0.02 15.0 0.5 9.2 6.4 0.0 3.3 2 1 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Peptidase_C39_2 PF13529.6 EAX86958.1 - 0.26 11.8 3.8 7.1 7.2 0.2 3.7 2 1 1 3 3 3 0 Peptidase_C39 like family UPF0270 PF06794.12 EAX86958.1 - 0.35 11.0 4.1 51 4.1 0.0 5.0 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0270) Phasin PF05597.11 EAX86958.1 - 0.67 10.0 6.9 0.66 10.0 0.5 3.4 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cob_adeno_trans PF01923.18 EAX86958.1 - 1.5 8.9 8.2 0.32 11.1 0.4 3.4 3 2 0 3 3 3 0 Cobalamin adenosyltransferase DUF1359 PF07097.11 EAX86958.1 - 9.1 6.6 10.9 2.4 8.4 1.1 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1359) PSP PF04046.16 EAX86959.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX86960.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX86961.1 - 0.012 16.0 0.9 0.023 15.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX86962.1 - 1.8e-21 75.9 15.5 6.3e-16 58.2 2.3 4.1 5 0 0 5 5 5 2 Phage tail repeat like Myb_DNA-binding PF00249.31 EAX86963.1 - 6.5e-25 87.1 0.2 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX86963.1 - 8e-20 70.8 0.2 1.3e-09 38.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX86963.1 - 8.4e-07 28.8 3.4 4.2e-06 26.6 0.0 2.8 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX86963.1 - 0.00053 20.0 0.8 0.28 11.2 0.2 2.8 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX86963.1 - 0.013 15.7 0.4 1.1 9.5 0.1 3.1 2 2 0 2 2 2 0 Rap1 Myb domain HxlR PF01638.17 EAX86963.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Rap1_C PF11626.8 EAX86963.1 - 0.097 12.8 0.1 2.8 8.1 0.1 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Na_sulph_symp PF00939.19 EAX86964.1 - 2e-22 79.9 41.1 2.9e-22 79.3 41.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAX86964.1 - 1e-19 70.9 62.5 2.8e-15 56.3 41.0 2.4 1 1 1 2 2 2 2 Citrate transporter Peptidase_C10 PF01640.17 EAX86964.1 - 0.15 12.3 0.4 0.31 11.3 0.1 1.6 2 0 0 2 2 2 0 Peptidase C10 family SPX PF03105.19 EAX86965.1 - 6e-05 23.1 9.8 0.00033 20.7 2.7 2.0 1 1 1 2 2 2 2 SPX domain Peptidase_C1_2 PF03051.15 EAX86965.1 - 0.021 13.6 0.8 0.03 13.1 0.3 1.5 1 1 1 2 2 2 0 Peptidase C1-like family CBM49 PF09478.10 EAX86965.1 - 0.06 13.7 0.1 0.088 13.1 0.1 1.6 1 1 0 1 1 1 0 Carbohydrate binding domain CBM49 TMEM154 PF15102.6 EAX86966.1 - 0.0006 19.7 0.1 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 EAX86966.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain ODV-E18 PF10717.9 EAX86966.1 - 0.012 15.5 0.1 0.036 13.9 0.1 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4625 PF15418.6 EAX86966.1 - 0.057 13.7 0.1 0.057 13.7 0.1 9.5 9 2 1 10 10 10 0 Domain of unknown function (DUF4625) EphA2_TM PF14575.6 EAX86966.1 - 0.067 14.1 0.0 0.2 12.6 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAX86966.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Amnionless EVC2_like PF12297.8 EAX86966.1 - 0.19 10.3 0.0 0.35 9.5 0.0 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein GCIP PF13324.6 EAX86967.1 - 0.016 14.8 0.1 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting tRNA-synt_His PF13393.6 EAX86967.1 - 0.022 14.1 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF948 PF06103.11 EAX86967.1 - 0.052 13.8 1.8 0.89 9.8 0.4 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GTP_cyclohydro2 PF00925.20 EAX86967.1 - 0.055 13.1 0.0 0.86 9.2 0.0 2.3 2 0 0 2 2 2 0 GTP cyclohydrolase II RPN5_C PF18098.1 EAX86967.1 - 0.15 12.2 0.1 0.48 10.6 0.1 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Ank_2 PF12796.7 EAX86968.1 - 1.8e-88 291.3 0.8 1.7e-19 70.2 0.0 5.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAX86968.1 - 1.9e-47 157.7 0.0 3.9e-06 27.1 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX86968.1 - 3.8e-41 138.6 0.1 1e-08 35.2 0.0 7.5 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX86968.1 - 1.4e-33 114.8 0.0 6.5e-09 36.2 0.0 5.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX86968.1 - 2.1e-30 101.4 0.0 0.0017 18.6 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat L_protein_N PF15518.6 EAX86968.1 - 9.3e-06 25.4 0.0 0.57 10.0 0.0 4.7 2 2 3 5 5 5 1 L protein N-terminus Ribosomal_L30 PF00327.20 EAX86968.1 - 0.29 11.0 4.1 51 3.9 0.0 5.0 5 0 0 5 5 5 0 Ribosomal protein L30p/L7e FYVE_2 PF02318.16 EAX86970.1 - 0.046 13.9 0.2 0.088 13.0 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger baeRF_family8 PF18851.1 EAX86972.1 - 0.082 13.0 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 MGDG_synth PF06925.11 EAX86972.1 - 0.13 12.3 12.5 0.88 9.7 0.4 3.9 3 0 0 3 3 3 0 Monogalactosyldiacylglycerol (MGDG) synthase baeRF_family3 PF18845.1 EAX86972.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Erf4 PF10256.9 EAX86972.1 - 8.5 6.5 10.7 6.6 6.9 0.4 4.0 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family Gly_rich PF12810.7 EAX86974.1 - 1.6e-10 41.3 0.4 2e-10 41.0 0.4 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX86975.1 - 3.3e-32 112.4 28.7 3.8e-32 112.1 28.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Pec_lyase PF09492.10 EAX86975.1 - 0.19 11.0 0.1 0.26 10.6 0.1 1.1 1 0 0 1 1 1 0 Pectic acid lyase Gly_rich PF12810.7 EAX86976.1 - 4.2e-17 62.9 20.2 4.8e-17 62.7 20.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Cytokin-bind PF09265.10 EAX86978.1 - 0.45 9.8 3.1 0.3 10.5 0.3 1.9 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Gly_rich PF12810.7 EAX86979.1 - 1.3e-45 156.2 36.0 1.6e-45 155.9 36.0 1.1 1 0 0 1 1 1 1 Glycine rich protein Pox_A32 PF04665.12 EAX86980.1 - 2.4e-05 24.0 2.5 3.8e-05 23.3 2.5 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX86980.1 - 0.0061 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX86980.1 - 0.027 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX86980.1 - 0.071 13.4 1.3 0.19 12.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) ARA70 PF12489.8 EAX86981.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator SBP PF03110.14 EAX86982.1 - 0.11 12.8 0.0 10 6.5 0.0 2.4 2 0 0 2 2 2 0 SBP domain TPR_14 PF13428.6 EAX86983.1 - 0.0003 21.4 0.0 6.9 7.8 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.14 EAX86983.1 - 0.00081 19.5 3.8 0.015 15.3 2.4 2.5 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EAX86983.1 - 2.8 8.8 4.5 34 5.4 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EAX86983.1 - 6.1 6.9 8.9 2.3 8.3 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 EAX86984.1 - 5e-46 155.2 10.2 1.7e-14 54.2 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX86984.1 - 2e-26 91.7 0.3 3e-11 43.3 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX86984.1 - 2.8e-26 91.5 0.9 2.4e-10 40.7 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX86984.1 - 2.1e-23 81.7 0.3 5.5e-05 23.4 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX86984.1 - 1.1e-20 71.5 0.3 0.0044 17.4 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Pox_E8 PF03394.13 EAX86984.1 - 0.11 12.0 0.5 4.6 6.7 0.0 2.7 2 1 2 4 4 4 0 Poxvirus E8 protein FBD PF08387.10 EAX86984.1 - 0.11 12.3 0.7 3.4 7.6 0.1 2.8 3 0 0 3 3 3 0 FBD PTR PF12789.7 EAX86985.1 - 9.3e-17 60.8 2.6 9.3e-17 60.8 2.6 3.9 5 1 1 6 6 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX86985.1 - 0.036 13.8 0.1 0.093 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX86985.1 - 0.1 12.6 2.5 1.5 8.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Peptidase_M8 PF01457.16 EAX86986.1 - 6.8e-24 84.4 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin FAM176 PF14851.6 EAX86986.1 - 0.0027 17.4 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 EAX86986.1 - 0.028 15.3 0.1 0.064 14.1 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Inhibitor_I53 PF11714.8 EAX86986.1 - 0.039 14.1 0.2 0.095 12.9 0.2 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin GP41 PF00517.17 EAX86986.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Synaptobrevin PF00957.21 EAX86986.1 - 0.16 11.8 7.1 0.14 12.0 5.4 1.7 2 0 0 2 2 2 0 Synaptobrevin DUF755 PF05501.11 EAX86986.1 - 6.3 7.1 12.4 12 6.2 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3287 PF11690.8 EAX86987.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Peptidase_M8 PF01457.16 EAX86988.1 - 7.5e-09 34.8 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Leishmanolysin EphA2_TM PF14575.6 EAX86988.1 - 0.00045 21.0 0.1 0.001 19.9 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rhabdo_glycop PF00974.18 EAX86988.1 - 0.00088 17.8 0.1 0.0013 17.3 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein TMEM119 PF15724.5 EAX86988.1 - 0.0049 17.0 0.0 0.0077 16.3 0.0 1.2 1 0 0 1 1 1 1 TMEM119 family Shisa PF13908.6 EAX86988.1 - 0.007 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 EAX86988.1 - 0.0075 16.2 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM154 PF15102.6 EAX86988.1 - 0.017 15.0 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 EAX86988.1 - 0.045 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FAM176 PF14851.6 EAX86988.1 - 0.053 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Protocadherin PF08374.11 EAX86988.1 - 0.056 13.4 0.2 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 Protocadherin Sigma_reg_N PF13800.6 EAX86988.1 - 0.075 13.3 0.6 0.26 11.6 0.5 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF515 PF04415.12 EAX86988.1 - 0.11 10.9 0.5 0.15 10.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cadherin_C_2 PF16492.5 EAX86988.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4834 PF16118.5 EAX86988.1 - 0.14 13.1 0.1 0.27 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM132D_C PF15706.5 EAX86988.1 - 0.14 11.9 0.4 0.32 10.8 0.4 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SCIMP PF15050.6 EAX86988.1 - 0.15 12.6 4.0 1.1 9.8 0.2 2.2 2 0 0 2 2 2 0 SCIMP protein Synaptobrevin PF00957.21 EAX86988.1 - 0.16 11.8 9.4 0.25 11.1 9.4 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF3827 PF12877.7 EAX86988.1 - 0.17 10.2 0.1 0.27 9.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GPS2_interact PF15784.5 EAX86991.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX86991.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF2939 PF11159.8 EAX86993.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX86993.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX86993.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Filamin PF00630.19 EAX86994.1 - 0.05 14.4 0.1 0.11 13.4 0.1 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat PapD_N PF00345.20 EAX86994.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain ubiquitin PF00240.23 EAX86997.1 - 1.6e-65 216.8 5.2 4.1e-32 109.8 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX86997.1 - 4e-37 125.9 6.9 4.4e-18 64.9 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX86997.1 - 2.7e-11 43.7 1.6 0.00037 20.9 0.2 3.1 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX86997.1 - 1.5e-07 31.2 0.4 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX86997.1 - 2.2e-07 31.2 0.3 0.026 14.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX86997.1 - 5.4e-05 23.3 0.0 0.49 10.5 0.0 2.5 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX86997.1 - 8.9e-05 23.0 0.1 0.42 11.2 0.1 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 EAX86997.1 - 0.0001 22.8 1.4 0.4 11.2 0.1 2.1 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 EAX86997.1 - 0.00015 21.8 7.6 5 7.2 0.1 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain DUF2870 PF11069.8 EAX86997.1 - 0.0042 17.4 0.0 6 7.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) RBD PF02196.15 EAX86997.1 - 0.0077 16.3 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain USP7_C2 PF14533.6 EAX86997.1 - 0.056 13.1 0.2 9.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal EstA_Ig_like PF18435.1 EAX86997.1 - 0.1 12.8 0.1 17 5.6 0.0 2.1 2 0 0 2 2 2 0 Esterase Ig-like N-terminal domain ubiquitin PF00240.23 EAX86998.1 - 3.2e-63 209.4 5.9 6.5e-32 109.1 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX86998.1 - 4.7e-35 119.2 6.3 7e-18 64.2 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX86998.1 - 1.1e-10 41.8 1.7 0.00079 19.8 0.1 3.0 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX86998.1 - 3.3e-07 30.2 0.5 0.028 14.4 0.0 2.1 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX86998.1 - 6e-07 29.7 0.6 0.038 14.3 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX86998.1 - 0.00013 22.1 0.0 0.68 10.1 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX86998.1 - 0.00016 22.2 0.1 0.54 10.9 0.1 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 EAX86998.1 - 0.00022 21.7 1.8 0.63 10.6 0.2 2.1 1 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 EAX86998.1 - 0.0023 17.9 6.9 6.8 6.8 0.1 3.9 4 0 0 4 4 4 2 Ubiquitin-like domain DUF2870 PF11069.8 EAX86998.1 - 0.0093 16.3 0.0 8.1 6.9 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2870) RBD PF02196.15 EAX86998.1 - 0.027 14.5 0.0 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain EstA_Ig_like PF18435.1 EAX86998.1 - 0.1 12.8 0.1 13 5.9 0.0 2.1 2 0 0 2 2 2 0 Esterase Ig-like N-terminal domain VWA_3 PF13768.6 EAX86999.1 - 1e-18 67.7 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX86999.1 - 2.3e-15 57.3 0.0 4.6e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EAX86999.1 - 8.9e-11 42.0 0.0 2.9e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EAX86999.1 - 4.6e-10 40.1 0.0 9.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Mor PF08765.11 EAX86999.1 - 0.068 13.2 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Mor transcription activator family Colicin_immun PF09204.10 EAX86999.1 - 1.1 9.8 5.1 0.33 11.5 0.6 2.4 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity DUF4107 PF13389.6 EAX87000.1 - 2e-66 223.1 2.1 2.7e-66 222.7 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX87001.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Choline_transpo PF04515.12 EAX87002.1 - 1e-12 47.9 22.2 1e-12 47.9 22.2 2.9 1 1 2 3 3 3 1 Plasma-membrane choline transporter FKBP_C PF00254.28 EAX87003.1 - 2e-11 44.0 0.0 2.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2797 PF10977.8 EAX87003.1 - 0.0069 16.3 0.0 0.0091 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) zf-RING_2 PF13639.6 EAX87004.1 - 0.0065 16.8 6.8 0.0065 16.8 6.8 7.7 6 1 1 7 7 7 2 Ring finger domain SRA PF18491.1 EAX87004.1 - 0.1 12.7 0.8 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 SET and RING associated domain zf-C2H2 PF00096.26 EAX87004.1 - 0.97 10.0 0.1 0.97 10.0 0.1 8.8 10 2 0 10 10 10 0 Zinc finger, C2H2 type PSP PF04046.16 EAX87005.1 - 0.074 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87006.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87007.1 - 0.021 15.3 0.9 0.043 14.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PhaP_Bmeg PF09602.10 EAX87008.1 - 0.052 13.5 0.1 0.6 10.0 0.1 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PHM7_cyt PF14703.6 EAX87008.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Homez PF11569.8 EAX87008.1 - 0.22 11.0 0.5 0.44 10.1 0.5 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_32 PF13565.6 EAX87009.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Ribosomal_60s PF00428.19 EAX87010.1 - 1.7 9.3 6.3 0.21 12.2 0.6 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3447 PF11929.8 EAX87011.1 - 6.1e-41 138.2 5.8 6.1e-41 138.2 5.8 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87011.1 - 9.7e-05 22.9 0.3 0.0035 17.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87012.1 - 6.3e-21 73.8 2.4 3.9e-05 23.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX87012.1 - 7.5e-21 74.2 1.1 2e-11 44.1 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87012.1 - 3.2e-20 72.5 8.0 1.4e-16 60.9 1.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87012.1 - 1.8e-18 66.4 3.4 5.1e-07 29.8 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87012.1 - 4.4e-13 48.1 1.5 0.009 16.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Mic1 PF07035.12 EAX87012.1 - 0.0025 17.6 0.1 0.12 12.1 0.0 2.4 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like PAZ_siRNAbind PF12212.8 EAX87012.1 - 0.0045 16.8 0.2 1.7 8.5 0.0 2.7 1 1 2 3 3 3 2 PAZ domain Ribosomal_S6 PF01250.17 EAX87012.1 - 0.056 13.7 0.2 3.2 8.1 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein S6 DUF1456 PF07308.13 EAX87012.1 - 0.077 13.3 0.1 7.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) PrmC_N PF17827.1 EAX87012.1 - 0.091 13.4 0.1 13 6.5 0.0 3.3 1 1 1 2 2 2 0 PrmC N-terminal domain Thioredoxin PF00085.20 EAX87014.1 - 2.9e-15 56.1 0.6 1e-12 48.0 0.4 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EAX87014.1 - 5e-11 42.8 13.2 9.6e-09 35.4 5.7 2.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAX87014.1 - 0.00063 20.2 1.4 0.0026 18.2 0.2 2.4 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX87014.1 - 0.00096 19.4 1.4 0.0038 17.5 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAX87014.1 - 0.0064 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EAX87014.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin DUF2380 PF09533.10 EAX87014.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Hid1 PF12722.7 EAX87015.1 - 0.85 7.7 11.8 0.99 7.4 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4108 PF13390.6 EAX87017.1 - 3.4e-63 211.8 5.9 3.8e-63 211.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX87018.1 - 2e-05 25.0 2.6 0.00011 22.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX87018.1 - 0.049 14.3 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PTR PF12789.7 EAX87019.1 - 1.3e-15 57.1 19.8 5.2e-09 36.0 6.2 4.3 5 0 0 5 5 5 2 Phage tail repeat like PA28_alpha PF02251.18 EAX87019.1 - 0.27 11.3 2.3 13 5.9 0.2 2.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit RecG_N PF17190.4 EAX87019.1 - 7 7.5 6.6 37 5.2 0.6 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain DUF3839 PF12943.7 EAX87021.1 - 5e-156 517.3 11.4 6.2e-156 517.0 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX87021.1 - 0.14 12.5 1.2 0.37 11.1 0.2 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit PapD_N PF00345.20 EAX87023.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX87024.1 - 0.019 15.4 0.6 0.025 15.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX87024.1 - 1.5 7.8 2.9 1.6 7.7 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX87024.1 - 1.7 8.6 6.2 1.8 8.6 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Zn_ribbon_2 PF12674.7 EAX87025.1 - 0.097 13.3 0.1 0.21 12.3 0.0 1.7 1 1 0 1 1 1 0 Putative zinc ribbon domain Gly-zipper_Omp PF13488.6 EAX87027.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX87027.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX87027.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX87027.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX87027.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ank_2 PF12796.7 EAX87028.1 - 2.9e-15 56.6 0.5 2.8e-07 31.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87028.1 - 3.1e-13 49.6 0.5 1.4e-05 25.2 0.0 3.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87028.1 - 1.5e-11 43.4 0.1 0.0019 18.5 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAX87028.1 - 1.8e-11 44.3 3.2 9.8e-05 22.8 0.0 4.5 2 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX87028.1 - 1.3e-07 31.4 10.6 0.00041 20.3 1.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank PF00023.30 EAX87028.1 - 3.3e-07 30.4 0.0 0.052 14.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DUF2431 PF10354.9 EAX87028.1 - 0.046 14.0 0.4 0.051 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Ank_2 PF12796.7 EAX87029.1 - 2.8e-34 117.5 12.1 8.3e-11 42.3 0.4 4.5 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87029.1 - 5.2e-32 109.8 14.5 0.00051 20.5 0.0 8.0 4 4 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87029.1 - 4.5e-24 81.9 11.8 0.0041 17.5 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX87029.1 - 1e-23 83.1 6.8 3.2e-05 24.1 0.1 7.0 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX87029.1 - 1.7e-16 59.8 7.7 0.017 15.5 0.1 7.7 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 EAX87029.1 - 5.7e-06 26.2 27.2 0.00014 21.8 1.7 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) DUF2431 PF10354.9 EAX87029.1 - 0.00073 19.8 2.0 0.081 13.2 0.2 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF2431) Ank_2 PF12796.7 EAX87030.1 - 9e-26 90.3 10.6 1.7e-11 44.6 0.5 4.7 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX87030.1 - 1.2e-22 79.6 3.8 1.2e-22 79.6 3.8 6.8 5 2 1 6 6 6 3 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX87030.1 - 2.7e-22 76.4 14.8 0.0035 17.7 0.1 7.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 EAX87030.1 - 2.2e-21 75.9 10.0 0.00011 22.7 0.2 6.1 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87030.1 - 6.6e-18 64.5 7.3 0.0019 18.4 0.1 6.3 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX87030.1 - 9.9e-17 60.6 4.9 0.00076 19.8 0.2 6.0 5 0 0 5 5 5 4 Ankyrin repeat DUF3718 PF12514.8 EAX87030.1 - 0.016 15.4 2.0 7.1 6.9 0.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3718) zf-C2H2_2 PF12756.7 EAX87031.1 - 0.0041 17.4 1.8 0.0041 17.4 1.8 3.5 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) Guanylate_cyc PF00211.20 EAX87032.1 - 1.4e-38 132.3 0.0 2.6e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX87032.1 - 1.1e-11 44.9 0.5 2.6e-11 43.7 0.5 1.7 1 0 0 1 1 1 1 PAS domain Collagen PF01391.18 EAX87032.1 - 6.6e-07 29.0 0.9 1.3e-06 28.1 0.9 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PAS_4 PF08448.10 EAX87032.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAX87032.1 - 0.0071 16.3 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX87032.1 - 0.014 14.8 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated RGI_lyase PF18370.1 EAX87033.1 - 2e-18 66.4 0.2 4.5e-18 65.3 0.2 1.6 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 EAX87033.1 - 1.8e-05 25.2 15.3 3.1e-05 24.5 3.4 4.1 4 1 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EAX87033.1 - 0.0067 15.8 0.1 1.4 8.3 0.0 2.7 3 0 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EAX87033.1 - 2.4 8.4 17.3 3.6 7.8 0.8 3.5 3 0 0 3 3 3 0 FG-GAP repeat UFD1 PF03152.14 EAX87034.1 - 2.6e-42 144.2 0.0 3.7e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EAX87034.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 TPR_MLP1_2 PF07926.12 EAX87035.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX87035.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX87035.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX87035.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family DUF745 PF05335.13 EAX87036.1 - 0.0035 17.1 8.5 0.0044 16.8 8.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF5588 PF17826.1 EAX87036.1 - 0.0052 15.7 0.9 0.0068 15.3 0.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) PCRF PF03462.18 EAX87036.1 - 0.06 13.2 5.6 0.083 12.7 5.6 1.2 1 0 0 1 1 1 0 PCRF domain Fib_alpha PF08702.10 EAX87036.1 - 0.064 13.4 14.1 0.037 14.2 9.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SH3_14 PF18343.1 EAX87036.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Dda helicase SH3 domain SesA PF17107.5 EAX87036.1 - 0.17 12.1 6.9 0.11 12.6 4.1 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Tropomyosin_1 PF12718.7 EAX87036.1 - 0.42 10.8 17.0 0.29 11.3 13.6 1.7 1 1 1 2 2 2 0 Tropomyosin like CTU2 PF10288.9 EAX87036.1 - 0.51 10.6 0.0 0.51 10.6 0.0 2.5 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF724 PF05266.14 EAX87036.1 - 1.4 8.7 11.4 2.1 8.1 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 EAX87036.1 - 2.1 7.8 19.7 6.5 6.1 19.6 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 Bap31_Bap29_C PF18035.1 EAX87036.1 - 2.5 8.2 9.8 0.35 10.9 0.3 2.9 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain AATF-Che1 PF13339.6 EAX87036.1 - 2.6 8.8 9.8 9.4 6.9 0.2 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Prominin PF05478.11 EAX87036.1 - 3.1 5.6 6.7 4 5.3 6.7 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 EAX87036.1 - 3.7 7.0 10.9 4.4 6.8 10.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EAX87036.1 - 5.2 4.9 10.2 6 4.6 10.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.19 EAX87036.1 - 5.4 6.6 16.3 7 6.3 8.2 2.1 1 1 1 2 2 2 0 GrpE DUF4061 PF13270.6 EAX87036.1 - 6.8 7.1 10.1 0.34 11.2 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Ank_5 PF13857.6 EAX87037.1 - 2.4e-12 46.8 0.0 3.6e-08 33.5 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87037.1 - 2.3e-08 34.5 0.0 8.2e-05 23.1 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87037.1 - 6.9e-08 32.9 0.1 0.00017 22.1 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87037.1 - 1.7e-07 30.9 0.2 0.0028 18.0 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 EAX87037.1 - 2.7e-07 30.5 3.2 5.2e-07 29.5 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX87037.1 - 5.7e-05 23.4 0.0 0.0022 18.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat ABC_tran PF00005.27 EAX87038.1 - 1.7e-25 90.1 0.0 3.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX87038.1 - 5e-11 43.0 0.3 0.00024 21.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX87038.1 - 2.1e-06 27.4 0.1 1.5e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAX87038.1 - 0.00012 22.6 1.4 0.00024 21.7 1.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAX87038.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAX87038.1 - 0.00022 20.9 0.2 0.00042 20.0 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EAX87038.1 - 0.0017 18.1 0.0 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 EAX87038.1 - 0.003 16.7 0.1 0.005 15.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.15 EAX87038.1 - 0.0031 17.4 0.1 0.056 13.3 0.0 2.7 3 1 0 3 3 3 1 NTPase AAA_16 PF13191.6 EAX87038.1 - 0.0041 17.5 0.0 0.0062 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.25 EAX87038.1 - 0.0066 16.1 0.1 0.012 15.3 0.1 1.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EAX87038.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EAX87038.1 - 0.011 15.6 0.1 0.034 14.1 0.0 1.8 3 0 0 3 3 1 0 NACHT domain DLIC PF05783.11 EAX87038.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_15 PF13175.6 EAX87038.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX87038.1 - 0.017 15.4 0.1 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAX87038.1 - 0.021 15.1 0.3 0.05 13.9 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAX87038.1 - 0.029 14.9 0.0 0.069 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX87038.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EAX87038.1 - 0.038 13.6 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87038.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EAX87038.1 - 0.049 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EAX87038.1 - 0.058 13.6 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EAX87038.1 - 0.06 13.3 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EAX87038.1 - 0.066 12.8 0.2 0.15 11.6 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EAX87038.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 EAX87038.1 - 0.069 12.9 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAX87038.1 - 0.073 12.7 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EAX87038.1 - 0.074 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EAX87038.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EAX87038.1 - 0.095 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Bac_DnaA PF00308.18 EAX87038.1 - 0.12 12.2 0.1 4.9 6.9 0.0 2.6 2 2 0 2 2 2 0 Bacterial dnaA protein RsgA_GTPase PF03193.16 EAX87038.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 EAX87038.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 EAX87039.1 - 2.2e-27 94.9 0.2 5e-13 49.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87039.1 - 7.1e-20 71.0 0.8 8.3e-12 45.2 0.1 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX87039.1 - 8.3e-06 25.8 0.1 0.11 12.5 0.0 2.7 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX87039.1 - 0.00011 22.1 1.3 0.37 10.7 0.2 2.3 2 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX87039.1 - 0.086 13.2 3.6 4.1 7.9 0.5 3.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4107 PF13389.6 EAX87042.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX87042.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX87043.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4106 PF13388.6 EAX87044.1 - 8.2e-91 305.3 5.8 9.1e-91 305.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF5406 PF17400.2 EAX87045.1 - 0.97 9.9 8.3 2.4 8.6 0.5 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5406) RIC3 PF15361.6 EAX87048.1 - 0.034 14.6 2.0 0.033 14.6 2.0 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GPS2_interact PF15784.5 EAX87048.1 - 0.037 14.5 1.2 0.048 14.1 1.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GPS2_interact PF15784.5 EAX87049.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Sec63 PF02889.16 EAX87050.1 - 1.8e-53 181.4 0.0 9.7e-43 146.2 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EAX87050.1 - 4.2e-16 59.2 0.0 8.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX87050.1 - 3.9e-08 33.5 0.0 7.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAX87050.1 - 9.8e-07 29.1 0.0 3.9e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAX87050.1 - 0.0076 16.5 0.1 0.05 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain Peptidase_S64 PF08192.11 EAX87051.1 - 2.3 6.6 25.3 2.7 6.4 25.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.13 EAX87051.1 - 6.1 5.1 19.7 6.8 4.9 19.7 1.1 1 0 0 1 1 1 0 Menin Ank_2 PF12796.7 EAX87052.1 - 0 1300.2 87.5 2.7e-19 69.5 0.3 20.4 1 1 30 31 31 31 31 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87052.1 - 5.6e-258 830.4 0.1 6.4e-12 45.8 0.0 25.0 9 6 22 32 32 31 31 Ankyrin repeats (many copies) Ank PF00023.30 EAX87052.1 - 2.5e-235 751.8 23.1 7e-06 26.3 0.0 37.8 38 0 0 38 38 38 37 Ankyrin repeat Ank_5 PF13857.6 EAX87052.1 - 2.7e-203 655.4 18.3 1e-08 35.3 0.0 34.1 2 2 34 36 36 36 36 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87052.1 - 1.4e-189 590.4 0.0 0.00013 22.1 0.0 37.3 37 0 0 37 37 37 36 Ankyrin repeat L_protein_N PF15518.6 EAX87052.1 - 4.1e-20 71.4 0.0 8.4 6.3 0.0 18.7 8 4 14 22 22 22 0 L protein N-terminus DUF3083 PF11281.8 EAX87052.1 - 5.8e-13 48.9 17.2 2.5 7.4 0.1 13.9 4 3 14 19 19 19 2 Protein of unknown function (DUF3083) Phage_holin_5_2 PF16079.5 EAX87052.1 - 3.8e-05 23.9 0.0 40 4.6 0.0 7.0 7 1 1 8 8 8 0 Phage holin family Hol44, in holin superfamily V Fer4_14 PF13394.6 EAX87052.1 - 0.00078 19.6 0.0 6.7e+02 0.4 0.0 9.4 9 5 6 15 15 11 0 4Fe-4S single cluster domain Wtap PF17098.5 EAX87052.1 - 0.0033 17.4 2.8 0.0063 16.5 2.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family APG6_N PF17675.1 EAX87052.1 - 0.013 16.0 10.5 0.027 15.0 10.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EAX87052.1 - 0.045 12.6 8.9 0.076 11.9 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 EAX87052.1 - 0.08 13.2 5.5 0.39 11.0 5.5 2.2 1 0 0 1 1 1 0 Flagellar FliJ protein Golgin_A5 PF09787.9 EAX87052.1 - 0.12 11.8 9.7 0.19 11.2 9.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2203 PF09969.9 EAX87052.1 - 0.14 12.8 3.4 0.32 11.7 3.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Muted PF14942.6 EAX87052.1 - 0.19 12.0 9.3 0.45 10.8 9.3 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 EAX87052.1 - 0.24 11.7 9.5 0.45 10.8 9.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 EAX87052.1 - 0.24 11.7 6.9 0.48 10.7 6.9 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 EAX87052.1 - 0.26 10.8 3.2 0.4 10.2 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WXG100 PF06013.12 EAX87052.1 - 0.33 11.2 2.2 0.45 10.8 1.2 1.7 2 0 0 2 2 1 0 Proteins of 100 residues with WXG GIT1_C PF12205.8 EAX87052.1 - 0.6 10.2 4.3 1.2 9.2 4.3 1.5 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term COG2 PF06148.11 EAX87052.1 - 0.78 9.8 5.0 0.63 10.1 3.0 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 EAX87052.1 - 1.6 9.0 11.1 1.2 9.4 7.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 EAX87052.1 - 2.4 7.3 6.1 4 6.6 6.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein Lectin_N PF03954.14 EAX87052.1 - 2.6 7.8 5.2 5.7 6.7 5.2 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Allexi_40kDa PF05549.11 EAX87052.1 - 2.9 7.3 5.8 5 6.6 5.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1664 PF07889.12 EAX87052.1 - 3.6 7.7 6.7 8.5 6.4 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EAX87052.1 - 4 7.7 12.3 10 6.4 11.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 EAX87052.1 - 4.3 7.5 12.1 27 4.9 12.1 2.2 1 1 0 1 1 1 0 Swi5 Prefoldin PF02996.17 EAX87052.1 - 5.2 7.0 12.3 1.4 8.8 5.3 3.2 1 1 2 3 3 3 0 Prefoldin subunit PTR PF12789.7 EAX87055.1 - 2.4e-24 85.2 14.1 2.4e-24 85.2 14.1 5.0 4 1 1 5 5 5 2 Phage tail repeat like PSP PF04046.16 EAX87057.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX87058.1 - 5.2e-158 523.8 12.4 6.5e-158 523.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87058.1 - 1.7 9.1 7.4 1.8 9.1 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX87059.1 - 6.8e-07 29.8 0.1 1.4e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87059.1 - 0.03 14.2 0.1 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX87060.1 - 1.9e-34 117.9 0.3 4.9e-34 116.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX87060.1 - 0.0014 18.7 0.1 0.0039 17.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX87060.1 - 0.0083 16.6 5.0 0.26 11.7 1.1 2.5 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Peptidase_S76 PF13611.6 EAX87060.1 - 0.061 13.7 0.7 7.6 6.9 0.0 3.0 2 2 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 DUF3839 PF12943.7 EAX87061.1 - 3.3e-156 517.9 12.2 3.8e-156 517.7 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX87061.1 - 0.053 13.7 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX87061.1 - 0.08 13.4 1.5 0.48 10.8 0.2 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX87061.1 - 0.16 12.3 3.0 9.5 6.6 0.1 3.3 3 2 1 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX87061.1 - 0.18 12.3 5.1 2.1 8.9 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX87061.1 - 0.2 11.5 1.3 0.46 10.3 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX87062.1 - 0.004 16.8 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87063.1 - 3.6e-71 238.6 3.3 4.7e-71 238.2 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Collagen_bind_2 PF12904.7 EAX87064.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAX87065.1 - 5.9e-71 237.9 3.6 8.5e-71 237.4 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX87066.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4108 PF13390.6 EAX87067.1 - 1.3e-56 190.5 6.7 1.5e-56 190.3 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX87067.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3464 PF11947.8 EAX87068.1 - 1.3 8.7 3.2 1.2 8.8 2.2 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Pox_A32 PF04665.12 EAX87069.1 - 6.7e-07 29.0 2.9 6.7e-07 29.0 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87069.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87069.1 - 5.2e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87069.1 - 0.00012 22.1 2.8 0.0003 20.9 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87069.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87069.1 - 0.0012 18.7 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87069.1 - 0.0019 17.9 0.4 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87069.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87069.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87069.1 - 0.089 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87069.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX87069.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX87070.1 - 9.2e-158 523.0 14.9 1.2e-157 522.6 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87070.1 - 0.089 13.2 1.7 0.38 11.2 0.2 2.1 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX87070.1 - 0.42 10.9 2.5 2.7 8.3 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX87070.1 - 1.1 9.8 7.6 2.4 8.7 0.7 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX87071.1 - 0.038 14.5 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87072.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pox_A32 PF04665.12 EAX87073.1 - 5.9e-05 22.6 4.3 0.00011 21.8 4.3 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX87073.1 - 0.0033 17.4 0.9 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX87073.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX87073.1 - 0.052 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PTR PF12789.7 EAX87075.1 - 1.6e-24 85.7 29.8 2.8e-23 81.7 7.7 5.8 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX87075.1 - 0.094 12.5 0.1 0.34 10.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX87076.1 - 0.077 13.5 0.5 0.16 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX87077.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87078.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX87079.1 - 7.3e-10 38.3 1.4 1.4e-09 37.4 1.4 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX87079.1 - 0.084 11.6 1.6 1.3 7.6 1.5 2.3 1 1 0 1 1 1 0 DNA polymerase family B PSP PF04046.16 EAX87080.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87081.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF563 PF04577.14 EAX87082.1 - 1.5e-23 84.0 0.5 2e-23 83.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) GAD-like PF08887.11 EAX87082.1 - 0.1 12.4 1.1 0.46 10.3 0.2 2.6 4 0 0 4 4 4 0 GAD-like domain FAR1 PF03101.15 EAX87083.1 - 0.021 15.5 0.1 0.043 14.5 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3839 PF12943.7 EAX87084.1 - 6.6e-156 516.9 12.2 8.3e-156 516.6 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX87084.1 - 0.097 12.5 0.9 0.41 10.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX87086.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87087.1 - 8.2e-72 240.6 3.4 1.2e-71 240.1 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_4 PF13637.6 EAX87088.1 - 3.4e-67 222.0 27.3 1.9e-11 44.2 0.5 10.2 6 4 5 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87088.1 - 7.1e-66 218.8 24.0 1e-17 64.5 1.9 6.9 4 1 2 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87088.1 - 2.1e-54 179.7 22.9 9.1e-09 35.4 0.5 13.7 14 0 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 EAX87088.1 - 2e-46 150.6 29.7 2e-05 24.6 0.1 14.8 15 1 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 EAX87088.1 - 2.3e-43 145.7 14.1 7.5e-10 38.9 0.2 8.2 4 1 4 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX87088.1 - 1.4e-08 34.6 1.5 1.4e-08 34.6 1.5 7.0 2 1 4 7 7 7 2 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EAX87088.1 - 0.0096 16.2 2.7 18 5.7 0.0 4.6 3 2 2 5 5 5 1 Ribosomal protein S6 LisH PF08513.11 EAX87088.1 - 0.038 14.0 1.8 0.59 10.2 0.2 3.3 3 0 0 3 3 3 0 LisH DUF3718 PF12514.8 EAX87088.1 - 0.41 10.8 6.4 3.5 7.8 0.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3718) PSP PF04046.16 EAX87089.1 - 0.055 13.3 0.5 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87090.1 - 0.095 13.3 6.2 11 7.2 0.3 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX87092.1 - 1.8e-23 82.3 11.0 1.8e-23 82.3 11.0 4.2 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX87092.1 - 0.055 13.2 0.9 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX87094.1 - 3e-157 521.3 11.8 3.7e-157 521.0 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87094.1 - 1 9.8 5.6 2.1 8.9 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX87094.1 - 4 8.0 6.6 1.4 9.5 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX87095.1 - 3.1e-05 24.5 0.2 0.00058 20.4 0.1 2.3 2 0 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX87095.1 - 0.059 12.9 0.7 1.4 8.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain MatE PF01554.18 EAX87096.1 - 3.5e-26 91.8 3.9 1.4e-25 89.8 0.6 2.3 2 1 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EAX87096.1 - 2.8e-08 33.9 3.8 2.8e-08 33.9 3.8 2.6 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain AAA_13 PF13166.6 EAX87097.1 - 0.0004 19.2 26.6 0.0004 19.2 26.6 4.2 1 1 4 5 5 5 2 AAA domain DUF4618 PF15397.6 EAX87097.1 - 0.0024 17.4 28.8 0.0024 17.4 28.8 5.4 2 1 3 6 6 6 2 Domain of unknown function (DUF4618) DUF5486 PF17588.2 EAX87097.1 - 0.015 15.2 1.6 0.069 13.0 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Filament PF00038.21 EAX87097.1 - 0.3 10.6 94.8 0.077 12.6 9.5 6.1 1 1 4 5 5 5 0 Intermediate filament protein WEMBL PF05701.11 EAX87097.1 - 0.92 8.1 76.6 0.065 11.9 14.4 3.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light MAD PF05557.13 EAX87097.1 - 4.1 5.7 104.5 0.4 9.0 7.9 3.7 1 1 2 3 3 3 0 Mitotic checkpoint protein Ras PF00071.22 EAX87098.1 - 8.2e-33 113.3 0.0 9.6e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87098.1 - 2.6e-17 63.2 0.1 4.6e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX87098.1 - 9.7e-08 31.7 0.1 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX87098.1 - 0.031 13.8 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX87098.1 - 0.042 13.7 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase Glyoxalase_5 PF14696.6 EAX87098.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal SWI2_SNF2 PF18766.1 EAX87098.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Bromodomain PF00439.25 EAX87099.1 - 4.6e-22 77.9 1.3 9.7e-22 76.9 1.3 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX87099.1 - 0.022 14.9 0.2 0.065 13.4 0.2 1.9 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation zf-met PF12874.7 EAX87100.1 - 3.2 8.3 4.6 7.7 7.1 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NPL PF17800.1 EAX87101.1 - 1.1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain His_Phos_2 PF00328.22 EAX87102.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) MetallophosC PF16370.5 EAX87102.1 - 0.041 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase His_Phos_2 PF00328.22 EAX87103.1 - 3.9e-14 52.8 0.0 1.3e-09 38.0 0.0 2.5 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) MRP-S32 PF10210.9 EAX87103.1 - 0.1 13.2 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 C2-set PF05790.15 EAX87103.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C2-set domain TMEM154 PF15102.6 EAX87104.1 - 0.0014 18.5 0.1 0.0015 18.4 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EAX87104.1 - 0.0017 18.2 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 EAX87104.1 - 0.0024 18.1 0.0 0.0028 17.9 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A Stevor PF17410.2 EAX87104.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 EAX87104.1 - 0.013 15.5 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ETRAMP PF09716.10 EAX87104.1 - 0.016 15.2 3.9 0.025 14.7 3.6 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5385 PF17359.2 EAX87104.1 - 0.03 13.9 0.2 0.043 13.4 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4448 PF14610.6 EAX87104.1 - 0.067 13.0 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TNFR_16_TM PF18422.1 EAX87104.1 - 5.7 7.0 8.2 44 4.1 8.2 2.1 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain His_Phos_2 PF00328.22 EAX87105.1 - 1.7e-10 40.8 0.2 3.6e-10 39.7 0.2 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_C1 PF00112.23 EAX87106.1 - 2.5e-40 138.9 0.4 2.7e-40 138.8 0.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX87106.1 - 0.00081 18.3 0.1 0.0011 17.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF4107 PF13389.6 EAX87108.1 - 1.7e-66 223.4 6.4 2.6e-66 222.8 6.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX87108.1 - 0.11 12.8 0.5 0.16 12.4 0.1 1.4 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta MFS_2 PF13347.6 EAX87109.1 - 0.00021 20.0 0.0 0.00021 20.0 0.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EAX87109.1 - 0.0026 16.7 0.2 0.0028 16.6 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 EAX87110.1 - 1.2e-31 108.6 0.5 1.8e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87110.1 - 1.6e-22 79.5 2.1 1.4e-15 57.3 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX87110.1 - 2.5e-07 30.7 6.1 0.00051 20.0 0.1 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX87110.1 - 8.8e-05 22.3 5.9 0.0019 18.1 0.5 2.8 1 1 1 2 2 2 2 Myb DNA-binding like DUF4424 PF14415.6 EAX87110.1 - 0.00048 19.5 0.4 0.00049 19.5 0.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4424) SANT_DAMP1_like PF16282.5 EAX87110.1 - 0.0024 18.0 1.1 0.065 13.4 0.1 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX87110.1 - 0.003 17.7 0.8 1.6 9.0 0.3 3.0 1 1 1 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 EAX87110.1 - 0.0042 17.2 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF489 PF04356.12 EAX87110.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) RTP801_C PF07809.11 EAX87110.1 - 0.1 12.5 0.5 12 5.8 0.1 2.3 2 0 0 2 2 2 0 RTP801 C-terminal region Ank_2 PF12796.7 EAX87111.1 - 0.0002 21.9 0.1 1.3 9.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87111.1 - 0.032 14.8 0.1 21 6.1 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 EAX87111.1 - 0.061 13.8 0.0 66 4.2 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat CPSase_C PF18302.1 EAX87111.1 - 5.8 7.7 7.6 16 6.4 0.0 3.8 4 0 0 4 4 4 0 Carbamoyl phosphate synthetase C-terminal domain DUF3839 PF12943.7 EAX87112.1 - 5.6e-79 265.0 9.2 7.1e-79 264.7 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX87113.1 - 6.6e-60 202.6 3.2 7.3e-60 202.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LuxT_C PF18285.1 EAX87114.1 - 0.04 14.5 0.1 1.2 9.7 0.0 2.8 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain Atx10homo_assoc PF09759.9 EAX87114.1 - 0.055 13.5 0.1 6.3 6.9 0.0 3.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain NSP2-B_epitope PF14757.6 EAX87114.1 - 0.13 11.9 1.2 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Peptidase_S51 PF03575.17 EAX87115.1 - 1.2e-46 159.0 0.0 1.4e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 SNO PF01174.19 EAX87115.1 - 0.0031 17.4 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EAX87115.1 - 0.0065 16.1 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain PTR PF12789.7 EAX87116.1 - 0.012 15.6 2.2 0.095 12.8 0.6 2.2 2 0 0 2 2 2 0 Phage tail repeat like NERD PF08378.11 EAX87116.1 - 0.086 13.3 0.1 0.25 11.8 0.0 1.7 1 1 1 2 2 2 0 Nuclease-related domain DUF2884 PF11101.8 EAX87116.1 - 0.09 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) LBR_tudor PF09465.10 EAX87117.1 - 0.00027 20.7 0.1 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EAX87117.1 - 0.014 15.3 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Inhibitor_I69 PF13734.6 EAX87117.1 - 0.015 15.7 0.1 0.028 14.9 0.1 1.4 1 0 0 1 1 1 0 Spi protease inhibitor Agenet PF05641.12 EAX87117.1 - 0.02 15.4 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Agenet domain DUF5097 PF17020.5 EAX87119.1 - 1.2 9.5 6.7 4.4 7.7 2.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5097) SopD PF11047.8 EAX87121.1 - 0.015 14.5 0.2 0.017 14.3 0.2 1.0 1 0 0 1 1 1 0 Salmonella outer protein D AAA_22 PF13401.6 EAX87122.1 - 4.5e-05 23.7 0.1 0.00027 21.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX87122.1 - 6.4e-05 23.0 2.9 0.00013 22.0 2.8 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87122.1 - 0.00039 20.2 0.0 0.00059 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87122.1 - 0.00055 19.8 0.9 0.0025 17.7 0.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX87122.1 - 0.0073 16.6 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87122.1 - 0.0087 15.8 0.5 0.2 11.4 0.0 2.4 1 1 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 EAX87122.1 - 0.045 13.2 0.1 0.074 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX87122.1 - 0.079 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX87122.1 - 0.11 12.9 0.1 0.37 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX87122.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX87122.1 - 0.18 12.1 4.3 5.2 7.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX87123.1 - 1.6e-35 121.3 1.7 2.1e-35 120.9 0.7 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX87123.1 - 0.019 15.6 0.0 0.065 13.9 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX87123.1 - 0.59 10.2 3.9 2.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein KilA-N PF04383.13 EAX87124.1 - 1e-41 141.3 0.1 1.6e-41 140.7 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX87125.1 - 6.5e-07 29.8 1.2 5.5e-06 26.9 0.2 2.3 2 1 0 2 2 2 1 T5orf172 domain DDE_Tnp_ISL3 PF01610.17 EAX87126.1 - 0.00053 19.8 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Transposase MULE PF10551.9 EAX87127.1 - 3.5e-07 30.5 1.1 3.5e-07 30.5 1.1 1.9 2 0 0 2 2 2 1 MULE transposase domain FANCI_S2 PF14676.6 EAX87127.1 - 0.14 12.5 0.3 21 5.4 0.0 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 Trypan_PARP PF05887.11 EAX87128.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mitofilin PF09731.9 EAX87133.1 - 6.3e-05 22.0 26.1 6.3e-05 22.0 26.1 3.9 3 1 0 3 3 3 1 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 EAX87133.1 - 0.00073 18.2 26.0 0.00073 18.2 26.0 2.7 3 0 0 3 3 3 1 Borrelia P83/100 protein Pox_A32 PF04665.12 EAX87134.1 - 1.6e-08 34.3 1.0 3.5e-08 33.2 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX87134.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX87134.1 - 0.065 13.1 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 VirK PF06903.12 EAX87135.1 - 0.032 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 VirK protein SNAP PF14938.6 EAX87136.1 - 0.00042 19.8 0.1 0.001 18.6 0.0 1.7 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF3447 PF11929.8 EAX87137.1 - 4e-37 126.0 3.5 4e-37 126.0 3.5 4.2 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87137.1 - 5.3e-20 71.8 0.5 3.5e-10 40.3 0.0 4.8 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87137.1 - 8e-14 51.8 0.6 0.00035 21.1 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87137.1 - 9.9e-08 31.7 0.1 1.1 10.1 0.0 6.3 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 EAX87137.1 - 5e-06 26.7 0.0 0.34 11.4 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EAX87137.1 - 3.3e-05 24.1 0.0 0.013 15.8 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeats (many copies) ATP13 PF12921.7 EAX87137.1 - 0.047 13.5 0.5 0.13 12.2 0.5 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase expression Ribosomal_L7Ae PF01248.26 EAX87138.1 - 8.6e-15 54.3 0.9 1.1e-14 53.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_tran_WecB PF03808.13 EAX87138.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L32e PF01655.18 EAX87138.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L32 MULE PF10551.9 EAX87139.1 - 3.9e-13 49.6 0.1 7.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX87139.1 - 0.081 12.6 1.1 0.14 11.9 1.1 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX87139.1 - 0.39 11.0 5.6 0.88 9.8 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX87139.1 - 0.71 9.6 5.3 1.1 9.0 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4107 PF13389.6 EAX87140.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX87141.1 - 0.01 15.5 0.2 0.028 14.1 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX87142.1 - 8.4e-153 506.7 14.0 1e-152 506.4 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX87142.1 - 0.06 13.6 0.8 0.43 10.9 0.2 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit APC_u14 PF16635.5 EAX87142.1 - 0.9 10.1 4.8 0.79 10.3 2.7 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX87142.1 - 4.8 7.7 7.6 4.7 7.7 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2457 PF10446.9 EAX87143.1 - 9.2 5.3 11.7 13 4.7 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HLH PF00010.26 EAX87145.1 - 0.00014 21.8 0.3 0.00044 20.1 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Gp-FAR-1 PF05823.12 EAX87145.1 - 0.0079 16.6 1.5 0.026 14.9 0.1 2.1 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Spectrin PF00435.21 EAX87145.1 - 0.052 14.0 0.3 0.052 14.0 0.3 2.0 3 0 0 3 3 3 0 Spectrin repeat HALZ PF02183.18 EAX87145.1 - 0.058 13.6 1.4 0.094 13.0 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper CLZ PF16526.5 EAX87145.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOG2 PF10428.9 EAX87145.1 - 0.62 9.2 10.7 0.77 8.9 10.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FH2 PF02181.23 EAX87145.1 - 1.3 8.1 5.1 13 4.8 0.3 2.4 1 1 0 2 2 2 0 Formin Homology 2 Domain TPR_MLP1_2 PF07926.12 EAX87147.1 - 0.013 15.6 19.7 0.013 15.6 19.7 3.8 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Fer2 PF00111.27 EAX87148.1 - 1.8e-11 43.8 1.3 2.7e-11 43.3 1.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4158 PF13700.6 EAX87149.1 - 0.065 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Cnd1 PF12717.7 EAX87149.1 - 0.32 11.0 10.0 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ank_2 PF12796.7 EAX87150.1 - 5e-17 62.3 1.8 7.6e-15 55.3 0.3 3.3 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX87150.1 - 2.7e-13 49.6 1.4 1.5e-08 34.5 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX87150.1 - 2.4e-11 42.8 2.0 0.00023 21.3 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX87150.1 - 1.2e-10 41.4 2.7 1.2e-07 31.8 0.0 3.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX87150.1 - 9.8e-10 38.4 0.6 0.003 17.9 0.4 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX87150.1 - 3e-08 34.1 0.1 2.8e-07 31.0 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AI-2E_transport PF01594.16 EAX87151.1 - 0.29 10.2 1.0 0.53 9.4 1.0 1.3 1 0 0 1 1 1 0 AI-2E family transporter DEAD PF00270.29 EAX87153.1 - 1.9e-40 138.5 0.0 4.1e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX87153.1 - 3.1e-29 101.5 1.0 1.3e-25 89.9 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAX87153.1 - 9.3e-08 32.3 0.0 5.9e-07 29.6 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAX87153.1 - 0.0023 17.2 0.1 0.0048 16.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AI-2E_transport PF01594.16 EAX87154.1 - 0.31 10.1 1.1 0.47 9.6 1.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter Peptidase_C1 PF00112.23 EAX87155.1 - 3.9e-76 256.0 14.3 4.6e-76 255.7 14.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX87155.1 - 6.6e-09 36.1 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAX87155.1 - 2.3e-05 23.4 5.6 0.0037 16.1 0.7 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Ndc1_Nup PF09531.10 EAX87156.1 - 0.62 8.7 7.5 0.74 8.4 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4519 PF15012.6 EAX87156.1 - 2.2 8.5 4.1 4.5 7.5 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_L38e PF01781.18 EAX87157.1 - 9.3e-22 76.9 1.3 1.1e-21 76.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF885 PF05960.11 EAX87158.1 - 9.6e-05 22.2 0.6 9.6e-05 22.2 0.6 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF885) DUF4140 PF13600.6 EAX87158.1 - 0.17 12.4 7.6 0.74 10.3 0.6 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1917 PF08939.10 EAX87158.1 - 0.18 11.7 8.1 0.26 11.1 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) MRP-S26 PF14943.6 EAX87158.1 - 0.28 11.1 26.1 0.15 12.0 11.8 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 CHD5 PF04420.14 EAX87158.1 - 0.33 10.8 10.4 2.6 7.9 0.6 2.4 2 0 0 2 2 2 0 CHD5-like protein DUF2203 PF09969.9 EAX87158.1 - 1.3 9.7 11.0 2.7 8.7 1.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 EAX87158.1 - 1.8 8.4 22.6 2.9 7.8 6.7 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Cob_adeno_trans PF01923.18 EAX87158.1 - 2.3 8.3 6.6 1 9.5 1.0 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase FliT PF05400.13 EAX87158.1 - 3.4 8.5 10.3 0.41 11.5 0.4 2.7 2 1 1 3 3 3 0 Flagellar protein FliT DUF573 PF04504.14 EAX87158.1 - 4.8 7.9 17.6 0.59 10.8 4.6 3.4 2 1 2 4 4 4 0 Protein of unknown function, DUF573 DUF1664 PF07889.12 EAX87158.1 - 7 6.7 10.4 2.1 8.4 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 EAX87158.1 - 9.2 5.5 14.1 3.6 6.8 3.5 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Snf7 PF03357.21 EAX87159.1 - 6.5e-07 29.1 21.8 1e-06 28.5 21.8 1.3 1 1 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 EAX87159.1 - 3 7.4 28.9 11 5.5 28.9 1.8 1 1 0 1 1 1 0 PspA/IM30 family DUF1771 PF08590.10 EAX87159.1 - 3 8.3 17.8 0.73 10.3 13.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1771) Dpy-30 PF05186.13 EAX87160.1 - 3.9e-07 29.6 0.0 2.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.17 EAX87160.1 - 3.3e-05 23.4 0.2 0.0051 16.4 0.1 2.5 2 0 0 2 2 2 2 Regulatory subunit of type II PKA R-subunit NAD_binding_10 PF13460.6 EAX87160.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding V_ATPase_I PF01496.19 EAX87160.1 - 0.033 12.1 2.4 1.8 6.4 0.0 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_6 PF13921.6 EAX87162.1 - 0.0018 18.5 0.2 0.0092 16.2 0.0 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX87162.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MCRS_N PF13325.6 EAX87162.1 - 0.08 12.9 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein rve PF00665.26 EAX87164.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RIH_assoc PF08454.11 EAX87164.1 - 0.22 11.4 2.8 4.1 7.3 0.7 2.3 2 0 0 2 2 2 0 RyR and IP3R Homology associated Gly-zipper_Omp PF13488.6 EAX87165.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper Zincin_2 PF10103.9 EAX87165.1 - 0.23 10.7 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX87165.1 - 0.69 10.2 6.2 1.1 9.5 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX87165.1 - 1.4 9.0 5.9 2.3 8.4 5.8 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif EamA PF00892.20 EAX87167.1 - 6e-12 45.9 36.2 6.7e-08 32.8 8.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Ycf70 PF17382.2 EAX87167.1 - 0.0049 17.2 0.5 0.82 10.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized Ycf70-like PRA-PH PF01503.17 EAX87168.1 - 0.13 12.7 2.9 0.91 10.0 3.4 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase AAA_11 PF13086.6 EAX87169.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX87169.1 - 0.0023 18.2 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX87169.1 - 0.0033 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX87169.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX87169.1 - 0.021 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX87169.1 - 0.05 13.2 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX87169.1 - 0.085 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EAX87169.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 EAX87169.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein Pox_A32 PF04665.12 EAX87170.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX87170.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX87170.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX87170.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pkinase PF00069.25 EAX87171.1 - 1.2e-53 182.1 0.1 1.5e-53 181.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87171.1 - 2.9e-29 102.1 0.0 3.9e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87171.1 - 2.9e-06 26.8 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like motB PF17613.2 EAX87171.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Modifier of transcription Chordopox_A35R PF05989.12 EAX87171.1 - 0.029 14.3 4.5 0.03 14.2 2.9 1.8 2 0 0 2 2 2 0 Chordopoxvirus A35R protein Prenyltrans PF00432.21 EAX87171.1 - 0.056 13.2 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat PDGLE PF13190.6 EAX87172.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 PDGLE domain S1-P1_nuclease PF02265.16 EAX87173.1 - 1.2e-44 153.0 0.3 1.4e-44 152.8 0.3 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease NodZ PF05830.11 EAX87173.1 - 0.032 13.0 0.3 0.045 12.6 0.3 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) DUF4108 PF13390.6 EAX87174.1 - 6.9e-79 262.7 11.9 7.9e-79 262.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ACP_PD PF04336.12 EAX87178.1 - 0.069 13.6 0.1 0.82 10.1 0.0 2.7 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase CENP-F_leu_zip PF10473.9 EAX87179.1 - 0.0002 21.4 9.9 0.0002 21.4 9.9 8.7 2 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 EAX87179.1 - 0.00023 21.4 12.0 0.00023 21.4 12.0 8.9 3 1 8 11 11 11 2 Flagellar FliJ protein Bacillus_HBL PF05791.11 EAX87179.1 - 0.0034 17.2 16.5 0.0034 17.2 16.5 8.0 4 2 4 8 8 8 1 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 EAX87179.1 - 0.028 14.6 106.7 0.45 10.7 9.5 7.4 2 1 3 6 6 6 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EAX87179.1 - 0.033 14.2 0.9 0.033 14.2 0.9 12.9 7 4 6 13 13 13 0 TATA element modulatory factor 1 DNA binding DUF5601 PF18151.1 EAX87179.1 - 1.3 9.4 10.7 0.3 11.4 1.2 4.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5601) FUSC PF04632.12 EAX87179.1 - 7.3 5.0 9.4 2.5 6.5 0.7 3.0 2 1 1 3 3 3 0 Fusaric acid resistance protein family Beta_helix PF13229.6 EAX87180.1 - 0.017 14.9 34.4 0.15 11.9 17.4 3.0 2 1 0 2 2 2 0 Right handed beta helix region MULE PF10551.9 EAX87181.1 - 1.5e-13 50.9 0.4 1.5e-13 50.9 0.4 2.4 3 0 0 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX87181.1 - 0.0083 15.9 0.4 0.034 13.9 0.2 1.9 1 1 1 2 2 2 1 Transposase DUF2960 PF11173.8 EAX87181.1 - 0.038 14.4 0.2 0.16 12.4 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Transposase_mut PF00872.18 EAX87181.1 - 0.11 11.4 2.5 0.3 9.9 2.5 1.7 1 1 0 1 1 1 0 Transposase, Mutator family Sec7 PF01369.20 EAX87182.1 - 9.3e-66 221.0 0.1 3.3e-65 219.2 0.1 2.0 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 EAX87182.1 - 1.6e-17 63.1 7.4 1.1e-16 60.4 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 EAX87182.1 - 2.7e-06 27.4 0.1 2.7e-06 27.4 0.1 4.0 4 2 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal v110 PF01639.17 EAX87182.1 - 0.0097 15.8 0.5 0.8 9.6 0.0 2.9 2 0 0 2 2 2 1 Viral family 110 Condensin2nSMC PF12422.8 EAX87182.1 - 0.12 12.5 7.0 3.3 7.9 0.0 4.8 6 0 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit Prok-RING_4 PF14447.6 EAX87183.1 - 3.9e-08 33.0 9.1 1.2e-07 31.4 9.1 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EAX87183.1 - 5.6e-08 32.5 8.7 1.9e-07 30.9 8.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAX87183.1 - 3.8e-05 23.6 10.9 3.8e-05 23.6 10.9 3.0 2 1 1 3 3 2 1 zinc-RING finger domain CENP-F_leu_zip PF10473.9 EAX87183.1 - 0.00015 21.8 2.0 0.00015 21.8 2.0 5.4 4 1 1 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_2 PF13639.6 EAX87183.1 - 0.00021 21.5 8.5 0.00073 19.8 8.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX87183.1 - 0.00035 20.4 7.0 0.0024 17.7 7.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX87183.1 - 0.0017 18.3 12.1 0.026 14.5 4.4 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAX87183.1 - 0.0049 16.7 11.8 0.01 15.7 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DHHW PF14286.6 EAX87183.1 - 0.018 14.4 0.0 0.071 12.4 0.1 2.0 2 0 0 2 2 2 0 DHHW protein zf-RING_4 PF14570.6 EAX87183.1 - 0.052 13.3 7.6 0.97 9.3 8.2 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF3440 PF11922.8 EAX87183.1 - 0.096 12.4 2.8 0.75 9.5 0.4 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF3440) zf-UDP PF14569.6 EAX87183.1 - 0.096 12.8 4.2 0.078 13.1 1.6 2.2 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn-C2H2_12 PF18112.1 EAX87183.1 - 0.1 13.1 3.6 1.1 9.7 0.3 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain TMP_2 PF06791.13 EAX87183.1 - 0.2 11.3 2.0 9.6 5.8 0.2 2.4 2 0 0 2 2 2 0 Prophage tail length tape measure protein Importin_rep_3 PF18806.1 EAX87183.1 - 0.26 11.4 1.7 0.62 10.2 0.1 2.5 3 0 0 3 3 2 0 Importin 13 repeat zf-C3HC4_4 PF15227.6 EAX87183.1 - 0.27 11.4 8.0 2.4 8.4 8.3 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SlyX PF04102.12 EAX87183.1 - 0.46 11.1 0.1 0.46 11.1 0.1 6.5 5 2 1 6 6 5 0 SlyX PSII_Pbs27 PF13326.6 EAX87183.1 - 0.63 10.4 5.2 9.3 6.6 0.1 3.5 3 0 0 3 3 3 0 Photosystem II Pbs27 TAFH PF07531.14 EAX87183.1 - 1.5 9.0 8.8 0.4 10.8 0.4 3.3 3 1 0 3 3 2 0 NHR1 homology to TAF Alpha_Helical PF18489.1 EAX87183.1 - 1.9 8.7 0.0 1.9 8.7 0.0 4.0 3 1 2 5 5 5 0 Alpha helical domain Tweety PF04906.13 EAX87183.1 - 2.1 6.9 8.9 3.9 6.0 0.9 2.6 2 0 0 2 2 2 0 Tweety kleA_kleC PF17383.2 EAX87183.1 - 2.5 8.5 10.6 5.9 7.3 0.4 3.3 3 0 0 3 3 2 0 Uncharacterized KorC regulated protein A SUA5 PF03481.13 EAX87183.1 - 3 8.4 5.4 3.6 8.2 0.1 3.0 3 0 0 3 3 3 0 Putative GTP-binding controlling metal-binding Syntaxin_2 PF14523.6 EAX87183.1 - 4.4 7.7 35.2 1.1 9.7 1.3 5.5 6 0 0 6 6 6 0 Syntaxin-like protein USP8_interact PF08941.10 EAX87183.1 - 5.2 6.9 17.3 5 6.9 0.3 3.8 2 1 0 3 3 3 0 USP8 interacting zf-C3HC4_5 PF17121.5 EAX87183.1 - 8.6 6.3 10.1 99 2.9 10.1 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PSP PF04046.16 EAX87184.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87185.1 - 0.053 14.1 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat RRM_1 PF00076.22 EAX87186.1 - 9.1e-15 54.2 0.1 2.1e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX87186.1 - 0.0093 15.6 0.1 0.017 14.7 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX87186.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ank_4 PF13637.6 EAX87187.1 - 0.06 14.0 0.1 0.21 12.2 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF5623 PF18536.1 EAX87188.1 - 0.091 13.1 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX87188.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX87189.1 - 1.4e-34 118.3 0.0 2.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain Plasmid_stab_B PF10784.9 EAX87190.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Plasmid stability protein DUF948 PF06103.11 EAX87194.1 - 0.83 10.0 7.8 0.95 9.8 7.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2121 PF09894.9 EAX87194.1 - 2.7 7.5 8.9 38 3.8 8.9 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) PspA_IM30 PF04012.12 EAX87194.1 - 6.5 6.3 8.8 2.5 7.6 1.0 1.9 1 1 1 2 2 2 0 PspA/IM30 family PriA_C PF18074.1 EAX87197.1 - 0.19 12.5 1.4 16 6.4 0.1 2.9 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain TAF4 PF05236.14 EAX87197.1 - 0.24 11.1 6.9 0.27 11.0 6.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1664 PF07889.12 EAX87197.1 - 0.4 10.7 3.5 0.38 10.8 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAX87197.1 - 0.7 10.1 8.3 0.33 11.1 3.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EAX87197.1 - 1 8.9 5.5 1.3 8.5 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 EAX87197.1 - 1.4 9.6 3.9 0.85 10.3 1.5 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1090 PF06476.12 EAX87197.1 - 1.6 8.9 11.9 0.15 12.2 6.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF4404 PF14357.6 EAX87197.1 - 5.7 7.7 9.8 3.7 8.2 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF563 PF04577.14 EAX87198.1 - 2.1e-27 96.6 0.8 4.6e-27 95.5 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF563 PF04577.14 EAX87199.1 - 3.9e-12 46.8 0.1 7.3e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TfuA PF07812.12 EAX87200.1 - 0.24 11.1 0.9 0.94 9.2 0.2 2.3 1 1 1 2 2 2 0 TfuA-like protein Tmemb_9 PF05434.11 EAX87201.1 - 0.35 10.8 2.7 0.6 10.0 2.6 1.6 1 1 0 1 1 1 0 TMEM9 JIP_LZII PF16471.5 EAX87202.1 - 0.0025 17.9 2.8 0.0025 17.9 2.8 5.7 4 2 4 8 8 8 2 JNK-interacting protein leucine zipper II DUF1515 PF07439.11 EAX87202.1 - 0.018 15.1 1.6 0.018 15.1 1.6 3.9 3 2 3 6 6 6 0 Protein of unknown function (DUF1515) STE PF02200.16 EAX87202.1 - 0.036 14.5 2.8 0.055 13.9 0.7 2.4 2 0 0 2 2 2 0 STE like transcription factor Baculo_PEP_C PF04513.12 EAX87202.1 - 0.71 9.9 32.8 0.2 11.7 13.1 4.4 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rit1_C PF17184.4 EAX87203.1 - 0.0072 15.8 0.9 0.012 15.1 0.9 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Syntaxin_2 PF14523.6 EAX87203.1 - 0.6 10.5 5.7 1.5 9.2 5.7 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Guanylate_cyc PF00211.20 EAX87204.1 - 5e-43 146.9 1.0 1.3e-42 145.6 0.1 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX87204.1 - 4.5e-07 30.1 0.1 1.2e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EAX87204.1 - 0.00084 19.3 0.8 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAX87204.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAX87204.1 - 0.033 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 PAS fold Wzy_C_2 PF11846.8 EAX87204.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF1904 PF08921.11 EAX87204.1 - 0.15 12.4 1.2 48 4.3 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1904) PapD_N PF00345.20 EAX87206.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX87206.1 - 0.066 13.2 0.4 0.098 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX87206.1 - 0.14 12.2 0.2 0.19 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4107 PF13389.6 EAX87209.1 - 3.3e-71 238.7 3.8 5e-71 238.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX87211.1 - 0.079 12.9 6.9 0.12 12.3 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX87211.1 - 2 8.9 5.4 2.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pro-NT_NN PF07421.11 EAX87214.1 - 0.057 13.7 1.4 0.088 13.1 1.4 1.2 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor AP4E_app_platf PF14807.6 EAX87214.1 - 0.065 13.6 0.9 0.11 12.9 0.9 1.4 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform TSC22 PF01166.18 EAX87214.1 - 1.4 9.3 4.8 3.2 8.2 4.8 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family LRR_5 PF13306.6 EAX87215.1 - 5.8e-10 39.2 4.9 4.3e-06 26.7 0.7 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF4107 PF13389.6 EAX87217.1 - 7.3e-73 244.1 3.0 9.5e-73 243.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX87218.1 - 5.6e-70 235.6 6.4 6.4e-70 235.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX87220.1 - 1.2e-06 28.1 0.1 2.6e-06 27.1 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX87222.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX87223.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX87224.1 - 2.3e-79 266.3 11.3 2.9e-79 265.9 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX87224.1 - 0.24 11.3 1.9 0.76 9.6 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase PSP PF04046.16 EAX87225.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87226.1 - 0.13 13.0 7.8 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX87226.1 - 4.3 7.3 8.2 4.7 7.2 8.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX87229.1 - 6.1e-118 392.6 6.9 7e-118 392.4 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PSP PF04046.16 EAX87230.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX87231.1 - 8.2e-57 189.8 10.7 5.2e-17 62.2 0.2 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87231.1 - 1.1e-49 166.2 9.8 1.3e-10 41.6 0.0 6.6 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX87231.1 - 1.4e-42 142.3 11.1 5.3e-05 23.5 0.0 9.5 9 1 1 10 10 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX87231.1 - 4.1e-39 132.1 5.0 7.4e-09 35.7 0.1 7.1 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87231.1 - 3.3e-36 119.2 4.5 0.00022 21.4 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat ZapB PF06005.12 EAX87231.1 - 0.00011 22.6 21.5 0.0035 17.8 10.0 2.6 1 1 1 2 2 2 2 Cell division protein ZapB TMF_DNA_bd PF12329.8 EAX87231.1 - 0.0003 20.7 19.2 0.0003 20.7 19.2 3.3 3 0 0 3 3 2 2 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 EAX87231.1 - 0.0023 18.2 22.5 0.023 15.0 8.5 3.8 3 0 0 3 3 3 2 Csm1 N-terminal domain Fez1 PF06818.15 EAX87231.1 - 0.0039 17.7 10.7 0.0039 17.7 10.7 2.2 2 0 0 2 2 1 1 Fez1 KASH_CCD PF14662.6 EAX87231.1 - 0.025 14.4 25.6 0.12 12.2 25.5 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 EAX87231.1 - 0.038 14.3 14.1 0.17 12.2 2.9 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 EAX87231.1 - 0.18 12.0 10.9 1.9 8.8 1.4 3.2 2 2 0 2 2 2 0 Homeobox associated leucine zipper GIT_CC PF16559.5 EAX87231.1 - 0.34 10.8 15.0 0.12 12.2 10.5 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DDHD PF02862.17 EAX87231.1 - 0.39 10.8 9.3 1.4 9.0 0.5 2.3 2 0 0 2 2 2 0 DDHD domain FOXP-CC PF16159.5 EAX87231.1 - 0.91 10.2 6.8 1.4 9.6 4.9 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain bZIP_1 PF00170.21 EAX87231.1 - 1.1 9.4 19.8 0.45 10.7 4.8 3.2 1 1 1 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 EAX87231.1 - 1.6 8.8 10.6 3.6 7.6 10.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Shugoshin_N PF07558.11 EAX87231.1 - 2.1 8.3 13.2 1.4 8.9 1.4 3.5 2 2 1 3 3 3 0 Shugoshin N-terminal coiled-coil region LMBR1 PF04791.16 EAX87231.1 - 2.6 6.8 5.3 5 5.9 5.3 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 EAX87231.1 - 3.6 7.4 28.2 1.2 9.0 6.9 3.5 1 1 2 3 3 3 0 Septum formation initiator TolA_bind_tri PF16331.5 EAX87231.1 - 3.9 7.6 15.4 8.3 6.6 8.4 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation APC_N_CC PF16689.5 EAX87231.1 - 6.9 6.8 15.6 0.036 14.1 1.8 3.1 2 1 1 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain DHR-2 PF06920.13 EAX87232.1 - 1.8e-141 472.4 8.3 3.1e-141 471.6 8.3 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EAX87232.1 - 2.1e-10 40.8 1.5 9.3e-10 38.6 0.2 2.8 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins MetOD2 PF18548.1 EAX87232.1 - 0.14 12.3 1.9 0.8 9.9 0.3 3.0 2 0 0 2 2 2 0 Metanogen output domain 2 Syntaxin_2 PF14523.6 EAX87232.1 - 2.4 8.6 8.6 9.9 6.6 1.2 3.2 3 0 0 3 3 3 0 Syntaxin-like protein IFT57 PF10498.9 EAX87233.1 - 0.027 13.5 1.2 0.034 13.1 0.4 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EAX87233.1 - 0.21 11.6 1.8 1.6 8.8 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EAX87233.1 - 0.39 11.2 6.6 2.8 8.5 1.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein IF4E PF01652.18 EAX87234.1 - 1.4e-39 135.4 0.7 1.8e-39 135.1 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANAPC4_WD40 PF12894.7 EAX87236.1 - 0.00011 22.4 0.2 5.8 7.3 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ParBc_2 PF08857.11 EAX87236.1 - 0.0039 17.3 0.1 0.012 15.6 0.1 1.8 2 0 0 2 2 2 1 Putative ParB-like nuclease Formyl_trans_C PF02911.18 EAX87236.1 - 0.012 15.9 0.0 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain Ge1_WD40 PF16529.5 EAX87236.1 - 0.017 14.1 0.7 2.5 7.0 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 EAX87236.1 - 0.032 15.1 2.8 1.2 10.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EAX87236.1 - 0.045 12.5 0.6 1.7 7.3 0.1 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Ank_2 PF12796.7 EAX87237.1 - 1.2e-58 195.6 6.0 1.2e-20 73.8 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87237.1 - 8.7e-28 95.5 0.1 2.9e-06 27.5 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX87237.1 - 8.7e-28 96.0 0.1 3.5e-07 30.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX87237.1 - 3.8e-24 84.7 0.0 3.3e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87237.1 - 2e-23 79.9 0.0 0.00015 21.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat DUF3083 PF11281.8 EAX87237.1 - 0.00018 20.9 0.0 0.15 11.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3083) Ribosomal_L17 PF01196.19 EAX87237.1 - 0.035 15.0 0.1 0.77 10.7 0.1 2.3 1 1 0 1 1 1 0 Ribosomal protein L17 FAD_binding_6 PF00970.24 EAX87237.1 - 0.061 13.7 0.1 26 5.2 0.0 3.0 1 1 2 3 3 3 0 Oxidoreductase FAD-binding domain Ribosomal_L30 PF00327.20 EAX87237.1 - 0.068 13.1 0.8 18 5.3 0.0 3.8 4 0 0 4 4 4 0 Ribosomal protein L30p/L7e DUF3839 PF12943.7 EAX87238.1 - 5.5e-155 513.9 12.9 6.7e-155 513.6 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX87238.1 - 0.029 14.1 3.2 0.045 13.4 0.6 2.7 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX87238.1 - 0.31 11.5 4.6 0.8 10.2 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX87238.1 - 0.45 11.1 4.4 1.6 9.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX87238.1 - 0.54 10.6 2.4 0.71 10.2 0.6 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Pox_A32 PF04665.12 EAX87239.1 - 5.2e-07 29.4 3.0 5.2e-07 29.4 1.4 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX87239.1 - 2.3e-05 24.2 0.4 0.34 10.6 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX87239.1 - 8.9e-05 22.8 0.2 0.00049 20.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX87239.1 - 0.00051 20.1 3.9 0.0012 18.8 4.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX87239.1 - 0.0013 18.5 0.7 0.0079 15.9 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX87239.1 - 0.0018 18.1 0.7 0.0037 17.1 0.7 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX87239.1 - 0.002 17.9 0.1 0.0036 17.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX87239.1 - 0.022 15.1 0.0 0.066 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX87239.1 - 0.056 12.9 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX87239.1 - 0.075 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAX87239.1 - 0.08 12.5 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX87239.1 - 0.083 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX87239.1 - 0.12 12.9 0.1 1.1 9.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX87239.1 - 0.16 12.2 4.9 4.3 7.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX87241.1 - 9e-63 210.5 6.0 1e-62 210.3 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MULE PF10551.9 EAX87242.1 - 0.0077 16.6 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX87242.1 - 0.047 14.1 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX87242.1 - 0.073 13.4 0.4 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 PWI domain PSP PF04046.16 EAX87243.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87244.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87245.1 - 0.069 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pkinase PF00069.25 EAX87246.1 - 8.8e-54 182.6 0.0 1.2e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87246.1 - 2.6e-34 118.7 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87246.1 - 8e-05 22.1 0.0 0.00089 18.7 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EAX87246.1 - 0.018 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EAX87246.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LRR_5 PF13306.6 EAX87247.1 - 1.7e-08 34.4 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87247.1 - 0.002 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat CortBP2 PF09727.9 EAX87247.1 - 0.0029 17.6 0.9 0.004 17.1 0.9 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 TMEM154 PF15102.6 EAX87247.1 - 0.016 15.1 0.6 0.029 14.3 0.6 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.6 EAX87247.1 - 0.054 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ank_2 PF12796.7 EAX87248.1 - 4.3e-07 30.4 0.1 6.7e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87248.1 - 1.6e-06 28.5 0.0 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF812 PF05667.11 EAX87248.1 - 0.00019 20.5 6.5 0.00024 20.1 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Ank PF00023.30 EAX87248.1 - 0.00095 19.5 0.0 0.0086 16.5 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EAX87248.1 - 0.001 19.4 0.1 0.068 13.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat CENP-F_leu_zip PF10473.9 EAX87248.1 - 0.0029 17.6 12.7 0.0029 17.6 12.7 1.5 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EAX87248.1 - 0.0048 15.6 7.1 0.0051 15.5 7.1 1.1 1 0 0 1 1 1 1 AAA domain Med4 PF10018.9 EAX87248.1 - 0.0049 16.6 4.5 0.0067 16.1 4.5 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Leu_zip PF15294.6 EAX87248.1 - 0.0055 16.3 8.0 0.0066 16.0 8.0 1.1 1 0 0 1 1 1 1 Leucine zipper eIF3_N PF09440.10 EAX87248.1 - 0.008 16.6 5.7 0.008 16.6 5.7 1.5 2 0 0 2 2 1 1 eIF3 subunit 6 N terminal domain Fzo_mitofusin PF04799.13 EAX87248.1 - 0.012 15.2 6.6 0.017 14.7 6.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1917 PF08939.10 EAX87248.1 - 0.02 14.8 1.1 0.026 14.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) TSC22 PF01166.18 EAX87248.1 - 0.024 14.9 4.0 0.045 14.1 4.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2935 PF11155.8 EAX87248.1 - 0.026 14.9 1.8 0.042 14.2 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DDHD PF02862.17 EAX87248.1 - 0.026 14.7 1.0 0.03 14.5 1.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF5082 PF16888.5 EAX87248.1 - 0.032 14.5 9.0 0.032 14.5 9.0 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EAX87248.1 - 0.043 12.9 5.3 0.05 12.7 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 EAX87248.1 - 0.048 13.8 8.9 0.14 12.3 6.2 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 EAX87248.1 - 0.05 14.1 13.7 0.095 13.2 13.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 EAX87248.1 - 0.05 12.2 7.7 0.06 11.9 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 EAX87248.1 - 0.058 12.3 9.4 0.079 11.8 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Dynamitin PF04912.14 EAX87248.1 - 0.065 12.6 7.9 0.08 12.3 7.9 1.0 1 0 0 1 1 1 0 Dynamitin PIEZO PF15917.5 EAX87248.1 - 0.11 11.9 6.2 0.14 11.7 6.2 1.1 1 0 0 1 1 1 0 Piezo Ank_5 PF13857.6 EAX87248.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ERM PF00769.19 EAX87248.1 - 0.12 12.1 11.4 0.2 11.4 11.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Lip_prot_lig_C PF10437.9 EAX87248.1 - 0.14 12.2 2.9 0.19 11.8 1.2 2.1 1 1 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus ABC_tran_CTD PF16326.5 EAX87248.1 - 0.14 12.4 13.5 0.39 11.0 13.3 1.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain ZapB PF06005.12 EAX87248.1 - 0.17 12.3 13.0 0.3 11.5 13.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EAX87248.1 - 0.19 11.5 10.0 0.31 10.8 10.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF883 PF05957.13 EAX87248.1 - 0.19 12.3 1.8 0.19 12.3 0.5 1.6 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) DUF2547 PF10818.8 EAX87248.1 - 0.2 12.6 1.2 0.36 11.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) LMBR1 PF04791.16 EAX87248.1 - 0.24 10.3 4.8 0.26 10.1 4.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Cluap1 PF10234.9 EAX87248.1 - 0.67 9.3 10.7 1.1 8.6 10.7 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4140 PF13600.6 EAX87248.1 - 0.78 10.2 3.5 1.4 9.4 3.5 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 EAX87248.1 - 0.9 9.6 5.5 1.7 8.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Vfa1 PF08432.10 EAX87248.1 - 1.5 9.1 13.3 2 8.7 13.3 1.2 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_A_type_inc PF04508.12 EAX87248.1 - 2 8.4 7.9 0.2 11.6 1.1 2.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat MCU PF04678.13 EAX87248.1 - 2.2 8.4 5.5 3.6 7.7 5.5 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Remorin_C PF03763.13 EAX87248.1 - 2.5 8.0 16.0 8.2 6.4 2.4 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region ACCA PF03255.14 EAX87248.1 - 2.8 7.8 7.6 3.4 7.5 7.6 1.3 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AAA_23 PF13476.6 EAX87248.1 - 3.6 8.0 18.1 99 3.3 17.7 2.0 2 0 0 2 2 2 0 AAA domain GrpE PF01025.19 EAX87248.1 - 3.8 7.1 15.8 17 5.0 15.8 1.8 1 1 0 1 1 1 0 GrpE DUF3987 PF13148.6 EAX87248.1 - 4.2 6.3 5.8 5.5 5.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TMPIT PF07851.13 EAX87248.1 - 8.1 5.6 10.6 8.8 5.5 10.6 1.2 1 1 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 EAX87249.1 - 2.8e-09 36.7 0.0 4.7e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87249.1 - 2.5e-06 27.0 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MatE PF01554.18 EAX87250.1 - 1.1e-24 87.0 30.3 9.5e-14 51.4 8.6 2.8 2 1 1 3 3 3 2 MatE Guanylate_cyc PF00211.20 EAX87252.1 - 1.8e-40 138.5 0.1 3.2e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX87252.1 - 6.6e-07 29.5 0.6 1.8e-06 28.2 0.6 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 EAX87252.1 - 5.3e-05 22.8 2.1 0.012 15.0 0.2 2.2 1 1 1 2 2 2 2 Heme NO binding associated PAS_8 PF13188.7 EAX87252.1 - 0.0001 22.2 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX87252.1 - 0.0037 17.2 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold Sld7_C PF18596.1 EAX87252.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Sld7 C-terminal domain PAS_4 PF08448.10 EAX87252.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF4064 PF13273.6 EAX87253.1 - 0.0013 19.0 7.1 0.067 13.5 1.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4064) TarH PF02203.15 EAX87253.1 - 0.0063 16.5 4.5 0.38 10.7 0.3 3.0 2 1 1 3 3 3 2 Tar ligand binding domain homologue PDR_CDR PF06422.12 EAX87253.1 - 0.067 13.1 0.6 2.6 8.0 0.0 2.6 2 1 0 2 2 2 0 CDR ABC transporter Tetraspanin PF00335.20 EAX87253.1 - 0.079 12.7 6.8 0.061 13.0 0.7 2.3 1 1 1 2 2 2 0 Tetraspanin family TMEM132D_C PF15706.5 EAX87253.1 - 0.3 10.9 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ATP_synt_H PF05493.13 EAX87253.1 - 0.36 11.3 2.4 2.7 8.5 0.2 2.4 2 0 0 2 2 2 0 ATP synthase subunit H Ac76 PF05814.11 EAX87253.1 - 0.91 9.6 14.2 1.9 8.5 4.0 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) Pox_LP_H2 PF03356.15 EAX87253.1 - 0.92 9.4 4.7 4.4 7.1 0.7 2.5 2 0 0 2 2 2 0 Viral late protein H2 YMF19 PF02326.15 EAX87253.1 - 4.7 8.1 11.9 0.35 11.7 1.4 3.2 3 0 0 3 3 3 0 Plant ATP synthase F0 DHHC PF01529.20 EAX87253.1 - 5.8 7.0 9.4 8.3 6.5 1.5 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_16 PF13191.6 EAX87254.1 - 0.00074 19.9 0.0 0.003 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EAX87254.1 - 0.0015 18.6 1.8 0.0029 17.7 0.0 2.5 3 1 1 4 4 4 1 AAA domain DUF563 PF04577.14 EAX87254.1 - 1.1 9.3 4.3 4 7.5 0.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF563) V-SNARE PF05008.15 EAX87255.1 - 6.4e-12 45.7 3.4 6.4e-12 45.7 3.4 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Synaptobrevin PF00957.21 EAX87255.1 - 1.3e-05 24.9 0.9 1.3e-05 24.9 0.9 2.0 2 0 0 2 2 2 1 Synaptobrevin DUF4407 PF14362.6 EAX87255.1 - 0.0013 18.1 7.3 0.0018 17.7 7.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) L31 PF09784.9 EAX87255.1 - 0.0022 18.4 2.0 0.38 11.2 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 Exonuc_VII_L PF02601.15 EAX87255.1 - 0.0086 15.7 9.8 0.011 15.3 9.8 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit SNARE PF05739.19 EAX87255.1 - 0.018 15.0 0.9 0.018 15.0 0.9 2.9 3 0 0 3 3 3 0 SNARE domain DUF3671 PF12420.8 EAX87255.1 - 0.036 14.1 0.5 0.1 12.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function FlaC_arch PF05377.11 EAX87255.1 - 0.087 13.2 3.3 7.6 7.0 0.2 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) RPW8 PF05659.11 EAX87255.1 - 0.1 12.3 3.5 4.4 7.0 0.1 2.8 2 2 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Osmo_CC PF08946.10 EAX87255.1 - 0.13 12.6 4.0 11 6.3 0.1 3.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil EF-hand_14 PF17959.1 EAX87255.1 - 0.19 12.1 3.6 0.21 12.0 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain FTCD_C PF04961.12 EAX87255.1 - 0.33 10.7 4.1 0.48 10.2 4.1 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Fungal_TACC PF12709.7 EAX87255.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.9 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 EAX87255.1 - 0.51 9.2 14.3 0.25 10.2 7.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein V-SNARE_C PF12352.8 EAX87255.1 - 0.58 10.5 6.7 0.66 10.3 1.5 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Allexi_40kDa PF05549.11 EAX87255.1 - 1.2 8.6 12.2 0.81 9.1 5.8 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein FapA PF03961.13 EAX87255.1 - 1.3 7.6 10.6 2 6.9 7.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CHASE3 PF05227.13 EAX87255.1 - 1.6 8.6 10.1 3.5 7.5 5.7 2.2 1 1 1 2 2 2 0 CHASE3 domain FUSC-like PF12805.7 EAX87255.1 - 2.6 7.1 6.5 0.45 9.6 2.1 1.9 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS MCU PF04678.13 EAX87255.1 - 3.4 7.7 7.8 39 4.3 7.8 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter SLATT_6 PF18169.1 EAX87255.1 - 4.3 6.9 7.1 8.3 6.0 0.1 2.6 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 TolA_bind_tri PF16331.5 EAX87255.1 - 4.4 7.4 12.0 0.37 10.9 0.4 2.8 2 2 0 2 2 2 0 TolA binding protein trimerisation P4Ha_N PF08336.11 EAX87255.1 - 6.5 6.8 10.6 14 5.7 3.3 3.0 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0449 PF15136.6 EAX87255.1 - 6.7 7.2 13.3 23 5.5 6.4 3.0 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 SlyX PF04102.12 EAX87255.1 - 7.9 7.2 8.2 3.3 8.4 0.4 3.1 2 2 1 3 3 3 0 SlyX DUF812 PF05667.11 EAX87256.1 - 0.0011 18.0 47.2 0.002 17.1 20.2 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF812) CHASE5 PF17149.4 EAX87256.1 - 0.011 15.7 7.4 0.18 11.7 0.1 3.7 3 0 0 3 3 3 0 Periplasmic sensor domain found in signal transduction proteins Atg14 PF10186.9 EAX87256.1 - 0.056 12.5 46.6 0.83 8.7 19.2 3.4 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 EAX87256.1 - 0.85 8.2 56.4 0.076 11.6 7.8 4.4 4 1 0 4 4 4 0 AAA domain Fez1 PF06818.15 EAX87256.1 - 0.89 10.0 48.6 0.38 11.2 4.1 4.0 3 1 1 4 4 4 0 Fez1 DUF885 PF05960.11 EAX87256.1 - 5.1 6.6 14.8 0.13 11.9 2.4 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF885) VPS9 PF02204.18 EAX87257.1 - 0.0001 22.5 0.1 0.00027 21.1 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Rhodanese PF00581.20 EAX87258.1 - 2.7e-14 53.6 0.0 4.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Trypan_PARP PF05887.11 EAX87259.1 - 0.022 14.8 5.9 0.033 14.2 5.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX87260.1 - 5.6e-156 517.1 14.5 7e-156 516.8 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87260.1 - 1.3 9.5 5.5 2 8.9 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5343 PF17278.2 EAX87261.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Syndecan PF01034.20 EAX87262.1 - 6e-06 26.1 0.3 1.1e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Syndecan domain DUF5305 PF17231.2 EAX87262.1 - 0.0012 18.3 0.4 0.0024 17.3 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Chlam_PMP PF02415.17 EAX87262.1 - 0.0029 18.0 12.8 6.7 7.4 0.1 6.0 5 0 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Adeno_E3_CR2 PF02439.15 EAX87262.1 - 0.01 15.6 0.6 0.022 14.5 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UBX PF00789.20 EAX87263.1 - 0.0059 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 EAX87264.1 - 1.6e-53 181.8 0.0 1.9e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87264.1 - 4.6e-15 55.6 0.0 6.2e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87264.1 - 0.0018 17.6 0.1 0.0038 16.6 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAX87264.1 - 0.057 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX87264.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAX87264.1 - 0.092 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX87264.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cation_efflux PF01545.21 EAX87265.1 - 3.2e-45 154.3 12.5 4.2e-45 153.9 12.5 1.2 1 0 0 1 1 1 1 Cation efflux family HEAT_2 PF13646.6 EAX87266.1 - 4.3e-07 30.2 0.1 0.0012 19.2 0.0 3.9 2 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EAX87266.1 - 0.00015 21.7 0.1 1.1 9.7 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat DUF4042 PF13251.6 EAX87266.1 - 0.01 15.5 0.7 0.49 10.1 0.0 3.5 2 1 1 4 4 4 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 EAX87266.1 - 0.088 13.1 0.1 3.4 8.0 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RtcB PF01139.17 EAX87267.1 - 3.2e-28 99.1 0.0 3.4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RtcB PF01139.17 EAX87268.1 - 4.9e-81 273.0 0.2 5.7e-81 272.8 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF917 PF06032.12 EAX87268.1 - 0.046 12.5 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) T5orf172 PF10544.9 EAX87269.1 - 7e-07 29.7 0.3 1.4e-06 28.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87270.1 - 5.2e-44 148.7 0.1 8.7e-44 147.9 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX87270.1 - 0.019 15.6 0.1 0.052 14.2 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family DUF3447 PF11929.8 EAX87272.1 - 3.7e-05 23.6 1.3 3.7e-05 23.6 1.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87272.1 - 8e-05 23.1 0.3 0.14 12.7 0.1 2.8 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87272.1 - 0.00081 19.7 0.1 1.5 9.6 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX87272.1 - 0.1 12.9 0.0 14 6.2 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DDE_1 PF03184.19 EAX87273.1 - 1.7e-16 60.3 0.0 3.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Gly_rich PF12810.7 EAX87274.1 - 2.3e-46 158.7 42.3 2.8e-46 158.4 42.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank PF00023.30 EAX87276.1 - 3.4e-24 84.2 0.9 4.1e-08 33.3 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX87276.1 - 7.2e-22 77.5 0.5 9e-12 45.3 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87276.1 - 6.2e-20 71.6 2.6 2.4e-18 66.5 2.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87276.1 - 5.8e-18 63.1 1.3 3.1e-07 30.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX87276.1 - 6.2e-13 48.7 0.7 3.2e-08 33.7 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF4313 PF14190.6 EAX87276.1 - 0.028 14.4 0.1 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Ank_2 PF12796.7 EAX87277.1 - 6e-80 263.9 41.8 3.4e-16 59.6 0.7 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87277.1 - 3.8e-55 183.6 11.9 2.9e-09 37.3 0.1 9.3 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87277.1 - 2.4e-53 177.5 14.3 4.7e-11 42.7 0.0 8.8 3 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87277.1 - 1.2e-51 166.6 20.4 5.8e-05 23.2 0.1 11.5 11 0 0 11 11 11 11 Ankyrin repeat Ank PF00023.30 EAX87277.1 - 1.2e-39 133.0 15.9 0.0003 21.1 0.2 11.0 11 0 0 11 11 11 8 Ankyrin repeat Abhydrolase_5 PF12695.7 EAX87277.1 - 0.023 14.4 1.5 25 4.6 0.0 4.2 2 2 1 4 4 4 0 Alpha/beta hydrolase family Pigment_DH PF06324.11 EAX87277.1 - 0.056 13.5 3.1 35 4.8 0.1 5.2 5 0 0 5 5 5 0 Pigment-dispersing hormone (PDH) NifU_N PF01592.16 EAX87277.1 - 0.065 13.4 1.9 27 4.9 0.0 4.8 3 1 3 7 7 7 0 NifU-like N terminal domain Aft1_HRR PF11787.8 EAX87277.1 - 0.094 13.9 0.0 10 7.4 0.0 3.6 3 2 1 4 4 3 0 Aft1 HRR domain Self-incomp_S1 PF05938.11 EAX87277.1 - 0.3 11.6 2.1 10 6.7 0.0 3.8 2 2 2 4 4 4 0 Plant self-incompatibility protein S1 PyrI PF01948.18 EAX87277.1 - 0.44 10.8 3.8 1.1 9.6 0.1 3.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Ank_2 PF12796.7 EAX87279.1 - 3.6e-16 59.5 0.5 1.9e-13 50.8 0.4 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87279.1 - 1.8e-15 55.5 0.5 4.7e-07 29.6 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX87279.1 - 2.2e-15 56.5 0.8 5.5e-08 32.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX87279.1 - 2.1e-13 50.5 0.8 5.5e-10 39.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX87279.1 - 7e-10 38.9 0.5 3.9e-05 23.9 0.2 4.2 4 0 0 4 4 4 1 Ankyrin repeat ATG16 PF08614.11 EAX87279.1 - 6.8e-08 33.0 7.6 9.4e-08 32.5 7.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.9 EAX87279.1 - 0.0013 19.1 6.5 0.0017 18.7 6.5 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein UPF0242 PF06785.11 EAX87279.1 - 0.0018 18.4 11.5 0.0026 17.9 11.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 EAX87279.1 - 0.0034 16.7 6.9 0.0049 16.2 6.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Lipoprotein_7 PF01540.16 EAX87279.1 - 0.0088 15.4 13.8 0.013 14.9 13.8 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein Uds1 PF15456.6 EAX87279.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.0 1 1 1 2 2 2 0 Up-regulated During Septation APG6_N PF17675.1 EAX87279.1 - 0.017 15.7 14.9 0.35 11.4 14.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 EAX87279.1 - 0.019 14.1 10.3 0.027 13.6 10.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EAX87279.1 - 0.025 15.2 8.1 0.19 12.4 1.4 2.8 2 1 1 3 3 2 0 SlyX DivIC PF04977.15 EAX87279.1 - 0.055 13.2 16.1 0.049 13.4 5.8 3.0 1 1 2 3 3 3 0 Septum formation initiator CENP-H PF05837.12 EAX87279.1 - 0.073 13.5 13.1 0.18 12.2 5.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Herpes_UL6 PF01763.16 EAX87279.1 - 0.076 11.5 8.8 0.095 11.2 8.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc7 PF08317.11 EAX87279.1 - 0.097 11.5 11.9 0.14 11.0 11.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 EAX87279.1 - 0.1 13.1 15.4 0.14 12.7 2.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 EAX87279.1 - 0.12 12.8 6.8 0.18 12.2 6.8 1.3 1 0 0 1 1 1 0 Fez1 DUF3552 PF12072.8 EAX87279.1 - 0.15 11.5 11.7 0.25 10.7 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FAM76 PF16046.5 EAX87279.1 - 0.18 11.2 10.8 0.25 10.7 10.8 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3450 PF11932.8 EAX87279.1 - 0.23 10.7 11.2 0.1 11.9 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HMMR_C PF15908.5 EAX87279.1 - 0.49 10.7 15.0 2 8.6 1.4 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Phage_GPO PF05929.11 EAX87279.1 - 0.93 9.1 5.3 0.97 9.0 4.2 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Mod_r PF07200.13 EAX87279.1 - 1.4 9.0 12.6 3.3 7.8 12.4 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad4 PF08650.10 EAX87279.1 - 1.6 8.8 7.8 0.71 9.9 2.4 2.8 1 1 1 2 2 2 0 DASH complex subunit Dad4 FlaC_arch PF05377.11 EAX87279.1 - 1.9 8.9 15.0 4.1 7.9 5.1 3.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 EAX87279.1 - 2 8.6 13.2 4.6 7.4 0.8 3.3 1 1 3 4 4 4 0 Basic region leucine zipper Csm1_N PF18504.1 EAX87279.1 - 2.2 8.7 12.7 0.59 10.5 7.2 2.5 1 1 2 3 3 3 0 Csm1 N-terminal domain TMPIT PF07851.13 EAX87279.1 - 2.2 7.5 7.4 4.2 6.5 7.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein CASP_C PF08172.12 EAX87279.1 - 2.7 7.2 11.3 2.6 7.3 2.1 2.2 1 1 1 2 2 2 0 CASP C terminal YabA PF06156.13 EAX87279.1 - 3 8.5 13.4 9.5 6.9 4.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 EAX87279.1 - 3.3 7.0 8.2 0.78 9.0 4.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cytochrom_B562 PF07361.11 EAX87279.1 - 3.5 8.3 8.8 3.7 8.3 3.6 2.2 1 1 1 2 2 2 0 Cytochrome b562 Cep57_MT_bd PF06657.13 EAX87279.1 - 5.9 7.4 10.7 36 4.9 7.2 2.8 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.8 EAX87279.1 - 6.1 6.9 22.8 1.3 9.0 14.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 EAX87279.1 - 7.6 6.3 12.1 13 5.5 11.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TLD PF07534.16 EAX87281.1 - 2.2e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 TLD zf-B_box PF00643.24 EAX87282.1 - 2.4e-15 56.4 17.7 1.4e-08 34.7 7.4 2.5 2 0 0 2 2 2 2 B-box zinc finger IBR PF01485.21 EAX87282.1 - 0.17 12.2 15.8 0.41 10.9 3.7 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Vps52 PF04129.12 EAX87282.1 - 0.37 9.5 2.3 0.52 9.0 2.3 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family GDA1_CD39 PF01150.17 EAX87283.1 - 6.8e-35 120.5 0.6 8.2e-35 120.3 0.6 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Phospholamban PF04272.14 EAX87283.1 - 0.071 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Phospholamban B56 PF01603.20 EAX87284.1 - 7.5e-72 242.6 8.3 9e-72 242.3 8.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4378 PF14309.6 EAX87285.1 - 0.043 14.2 0.1 0.24 11.8 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) UCH PF00443.29 EAX87286.1 - 2.5e-49 168.1 0.3 4e-49 167.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX87286.1 - 2.9e-17 63.3 0.3 4.5e-16 59.3 0.3 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EAX87286.1 - 5e-16 59.0 0.1 8.4e-14 51.8 0.0 2.7 1 1 1 2 2 2 2 Ubiquitin-specific protease C-terminal DUF16 PF01519.16 EAX87286.1 - 0.59 10.7 3.2 1.3 9.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Ank_2 PF12796.7 EAX87287.1 - 1.4e-52 176.2 9.9 3.1e-13 50.1 2.9 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87287.1 - 6.6e-48 160.5 8.3 8.4e-09 35.8 0.0 8.7 4 1 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87287.1 - 2.3e-44 148.8 11.0 1.5e-07 31.6 0.3 8.7 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87287.1 - 2.3e-36 119.7 6.5 0.00019 21.6 0.1 11.6 12 1 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 EAX87287.1 - 7e-35 118.0 8.7 0.00025 21.4 0.3 11.4 11 1 1 12 12 12 7 Ankyrin repeat Myb_DNA-binding PF00249.31 EAX87288.1 - 4.8e-21 74.7 0.2 6.9e-12 45.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87288.1 - 6.3e-18 64.8 0.6 2.4e-09 37.3 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX87288.1 - 0.0038 17.1 0.1 0.0081 16.0 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like AreA_N PF07573.11 EAX87288.1 - 0.14 12.8 0.1 20 5.9 0.0 2.3 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus Orf78 PF06024.12 EAX87289.1 - 0.0042 17.4 0.3 0.0082 16.4 0.3 1.5 1 0 0 1 1 1 1 Orf78 (ac78) MG2 PF01835.19 EAX87289.1 - 0.0057 17.1 1.2 0.64 10.5 0.1 3.6 3 1 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 EAX87289.1 - 0.0062 16.8 2.0 0.89 9.8 0.2 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4625) TMEM154 PF15102.6 EAX87289.1 - 0.02 14.8 3.1 0.037 13.9 3.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family CD20 PF04103.15 EAX87289.1 - 0.048 13.8 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 CD20-like family Calcyon PF06387.11 EAX87289.1 - 0.064 13.2 1.1 0.11 12.4 1.1 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Glycophorin_A PF01102.18 EAX87289.1 - 0.069 13.4 0.6 0.16 12.2 0.6 1.6 1 0 0 1 1 1 0 Glycophorin A DUF4448 PF14610.6 EAX87289.1 - 0.087 12.6 1.8 0.14 11.9 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 EAX87289.1 - 0.26 11.2 5.9 0.35 10.7 5.9 1.2 1 0 0 1 1 1 0 Rifin ETRAMP PF09716.10 EAX87289.1 - 1.1 9.4 4.2 0.26 11.3 0.3 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF5383 PF17355.2 EAX87289.1 - 2.2 8.7 7.1 0.26 11.7 1.4 2.3 1 1 2 3 3 3 0 Family of unknown function (DUF5383) MULE PF10551.9 EAX87291.1 - 4.9e-09 36.5 0.2 1.1e-08 35.4 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX87291.1 - 0.052 14.3 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Baculo_E66 PF04850.12 EAX87291.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein M16C_assoc PF08367.11 EAX87293.1 - 4.3e-15 55.5 5.1 1e-14 54.3 5.1 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAX87293.1 - 8e-14 52.1 3.8 4.3e-12 46.4 2.1 3.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAX87293.1 - 5.9e-11 42.6 0.3 3.9e-10 39.9 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HARP PF07443.13 EAX87293.1 - 0.48 10.1 5.6 0.14 11.8 0.6 2.7 3 0 0 3 3 3 0 HepA-related protein (HARP) SF3a60_bindingd PF12108.8 EAX87293.1 - 2.3 8.2 8.4 0.24 11.3 0.4 2.9 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain RESP18 PF14948.6 EAX87294.1 - 0.05 13.9 0.3 0.088 13.1 0.3 1.4 1 0 0 1 1 1 0 RESP18 domain SUKH_5 PF14567.6 EAX87295.1 - 0.021 14.5 15.3 0.22 11.3 1.4 4.8 3 1 2 5 5 5 0 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 EAX87295.1 - 0.24 11.8 15.3 3 8.3 6.1 4.0 2 2 1 3 3 3 0 SMI1-KNR4 cell-wall Pox_A3L PF05288.11 EAX87295.1 - 0.33 11.0 2.7 29 4.8 0.1 3.5 3 1 2 5 5 5 0 Poxvirus A3L Protein DUF4108 PF13390.6 EAX87296.1 - 7.1e-54 181.6 7.9 7.9e-54 181.5 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX87298.1 - 6.4e-07 29.1 2.6 6.4e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87298.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87298.1 - 6.9e-05 22.6 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87298.1 - 0.00012 22.2 2.9 0.00027 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87298.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87298.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87298.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87298.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87298.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87298.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87298.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX87298.1 - 0.4 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX87299.1 - 2e-41 140.4 0.8 3.8e-41 139.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX87299.1 - 0.021 15.4 0.1 0.054 14.1 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX87300.1 - 7.3e-07 29.7 0.2 1.5e-06 28.7 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain zf-C4H2 PF10146.9 EAX87301.1 - 0.02 15.2 17.8 0.02 15.2 17.8 2.4 1 1 0 2 2 2 0 Zinc finger-containing protein YabA PF06156.13 EAX87301.1 - 0.037 14.7 6.9 0.037 14.7 6.9 3.6 1 1 2 3 3 3 0 Initiation control protein YabA Lebercilin PF15619.6 EAX87301.1 - 0.77 9.4 53.1 3.7 7.2 32.6 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MHB PF16525.5 EAX87301.1 - 2.4 8.5 7.4 0.87 9.9 1.4 2.8 2 1 0 2 2 2 0 Haemophore, haem-binding DUF4201 PF13870.6 EAX87301.1 - 2.5 7.8 48.8 0.32 10.7 18.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Glyco_trans_1_4 PF13692.6 EAX87302.1 - 1.8e-08 34.9 0.0 2.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAX87302.1 - 7.7e-08 32.5 0.1 1.3e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EAX87302.1 - 1.8e-07 30.9 0.0 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAX87302.1 - 8e-05 23.1 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EAX87302.1 - 0.033 14.6 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TMP PF05017.14 EAX87304.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87305.1 - 0.074 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX87306.1 - 2.5e-155 515.0 15.6 3.1e-155 514.7 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87306.1 - 0.093 13.2 1.5 0.35 11.3 0.3 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX87306.1 - 0.19 12.3 5.0 0.65 10.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX87306.1 - 0.44 11.0 7.7 2.1 8.8 1.0 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX87306.1 - 5.4 7.4 7.1 12 6.2 0.1 3.7 3 2 0 3 3 3 0 Tup N-terminal T5orf172 PF10544.9 EAX87307.1 - 3.3e-05 24.4 0.2 9.4e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87307.1 - 0.0045 16.8 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX87307.1 - 0.016 14.7 0.5 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX87308.1 - 9.9e-156 516.3 13.2 1.3e-155 515.9 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87308.1 - 0.051 14.0 3.4 1 9.8 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GalP_UDP_transf PF01087.22 EAX87308.1 - 0.3 11.5 2.4 3.4 8.0 0.8 2.4 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Tup_N PF08581.10 EAX87308.1 - 1.9 8.9 7.3 13 6.2 0.1 3.9 4 2 1 5 5 5 0 Tup N-terminal Amidase02_C PF12123.8 EAX87309.1 - 0.022 14.4 0.1 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87310.1 - 4.1e-71 238.4 4.0 6.1e-71 237.8 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF563 PF04577.14 EAX87312.1 - 3.9e-39 134.9 1.2 8.3e-39 133.9 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sybindin PF04099.12 EAX87313.1 - 8e-37 126.3 0.2 8.9e-37 126.2 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAX87313.1 - 2.3e-05 24.5 0.1 2.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NAD_binding_10 PF13460.6 EAX87314.1 - 4.6e-37 127.7 0.0 5.5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAX87314.1 - 1.7e-10 40.8 1.4 3.1e-10 40.0 1.4 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAX87314.1 - 2.9e-08 33.5 1.2 4e-08 33.0 1.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAX87314.1 - 4.9e-05 22.5 0.2 6.4e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 EAX87314.1 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EAX87314.1 - 0.0082 15.3 1.0 0.22 10.6 1.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EAX87314.1 - 0.01 15.3 0.2 0.016 14.7 0.2 1.4 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 EAX87314.1 - 0.031 14.2 0.2 0.047 13.7 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 EAX87314.1 - 0.05 14.2 0.2 0.086 13.4 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EAX87314.1 - 0.071 13.2 0.1 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 EAX87314.1 - 0.085 13.3 0.2 0.16 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_S13 PF00416.22 EAX87314.1 - 0.089 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DUF1664 PF07889.12 EAX87315.1 - 0.0033 17.5 0.5 0.0049 16.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4854 PF16146.5 EAX87315.1 - 0.0072 16.6 0.7 0.016 15.5 0.5 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4854) Muted PF14942.6 EAX87315.1 - 0.013 15.9 0.7 0.017 15.5 0.7 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein UPF0184 PF03670.13 EAX87315.1 - 0.017 15.5 1.3 0.031 14.7 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) UPF0449 PF15136.6 EAX87315.1 - 0.065 13.7 1.5 0.19 12.2 1.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Pantoate_ligase PF02569.15 EAX87315.1 - 0.076 12.2 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Tn7_Tnp_TnsA_C PF08721.11 EAX87315.1 - 0.22 12.2 2.5 2.8 8.7 0.1 2.3 1 1 1 2 2 2 0 TnsA endonuclease C terminal TMPIT PF07851.13 EAX87315.1 - 0.33 10.2 1.8 0.43 9.8 1.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Sec7 PF01369.20 EAX87316.1 - 2.2e-06 27.5 0.2 3.9e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain DUF3839 PF12943.7 EAX87317.1 - 1e-119 398.4 10.4 1.3e-119 398.1 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87317.1 - 0.055 13.9 1.9 11 6.6 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ras PF00071.22 EAX87318.1 - 1.3e-59 200.5 0.2 1.6e-59 200.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87318.1 - 3.4e-36 124.1 0.3 7.6e-36 123.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX87318.1 - 1.1e-13 51.1 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX87318.1 - 2.3e-05 24.5 0.6 9.4e-05 22.5 0.1 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX87318.1 - 8.9e-05 22.9 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EAX87318.1 - 0.00033 20.2 0.1 0.0035 16.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX87318.1 - 0.00098 19.1 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EAX87318.1 - 0.0011 18.5 0.1 0.0084 15.6 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX87318.1 - 0.005 16.2 0.0 0.0097 15.3 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EAX87318.1 - 0.0062 16.8 0.1 0.034 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAX87318.1 - 0.0065 16.2 0.2 0.027 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 EAX87318.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EAX87318.1 - 0.018 14.9 0.0 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EAX87318.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX87318.1 - 0.04 13.2 0.1 0.099 11.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 EAX87318.1 - 0.045 13.7 0.1 0.068 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EAX87318.1 - 0.062 13.8 0.6 0.27 11.7 0.6 2.0 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EAX87318.1 - 0.083 13.1 0.1 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAX87318.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 EAX87318.1 - 0.093 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EAX87318.1 - 0.11 13.0 0.1 0.32 11.4 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PSP PF04046.16 EAX87319.1 - 0.12 12.3 1.6 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87320.1 - 0.55 11.1 5.1 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX87321.1 - 1.9e-156 518.7 12.7 2.4e-156 518.4 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87321.1 - 0.022 15.2 1.8 0.11 13.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX87321.1 - 0.69 10.4 7.3 1.9 9.0 0.7 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX87321.1 - 1.7 9.2 6.5 0.65 10.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNApol_Exo PF18136.1 EAX87322.1 - 0.48 9.5 3.4 0.18 10.9 0.4 1.8 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF4106 PF13388.6 EAX87323.1 - 1.5e-274 910.5 21.9 1.5e-274 910.5 21.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Amidase02_C PF12123.8 EAX87324.1 - 0.00024 20.7 0.1 0.00073 19.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87325.1 - 6.9e-53 179.1 0.6 1.1e-52 178.4 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Glyco_hydro_47 PF01532.20 EAX87326.1 - 1.2e-11 44.2 0.3 1.7e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Tsp45I PF06300.12 EAX87326.1 - 0.036 13.6 2.7 0.04 13.5 0.6 2.0 2 0 0 2 2 2 0 Tsp45I type II restriction enzyme DUF489 PF04356.12 EAX87327.1 - 0.0086 16.1 0.6 0.27 11.2 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF489) MOZ_SAS PF01853.18 EAX87328.1 - 3.6e-70 235.3 0.0 3.6e-70 235.3 0.0 1.6 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EAX87328.1 - 5.7e-20 70.7 3.0 1.3e-19 69.6 3.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAX87328.1 - 1.5e-05 24.7 0.1 3.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 EAX87328.1 - 0.011 16.6 1.2 0.034 15.0 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger FR47 PF08445.10 EAX87328.1 - 0.025 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 EAX87328.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAX87328.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_jaz PF12171.8 EAX87328.1 - 0.18 12.2 3.0 0.47 10.8 3.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HEAT PF02985.22 EAX87330.1 - 0.00068 19.7 0.1 1.4 9.4 0.0 3.3 2 0 0 2 2 2 2 HEAT repeat IBN_N PF03810.19 EAX87330.1 - 0.0024 17.7 4.1 0.25 11.3 0.4 3.6 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cauli_DNA-bind PF03310.13 EAX87330.1 - 0.022 14.8 2.9 0.16 12.0 0.1 3.4 3 0 0 3 3 3 0 Caulimovirus DNA-binding protein DUF2785 PF10978.8 EAX87330.1 - 0.079 12.7 0.0 0.47 10.2 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) UNC45-central PF11701.8 EAX87330.1 - 0.19 11.7 26.7 1.3 9.0 1.5 7.6 3 2 3 6 6 6 0 Myosin-binding striated muscle assembly central VSP PF03302.13 EAX87331.1 - 0.00012 21.1 4.2 0.00021 20.3 4.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EAX87331.1 - 0.00076 20.0 0.2 0.002 18.7 0.2 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage PARM PF17061.5 EAX87331.1 - 0.007 16.6 0.4 0.0098 16.1 0.4 1.2 1 0 0 1 1 1 1 PARM RIFIN PF02009.16 EAX87331.1 - 0.013 15.4 1.0 0.019 14.9 1.0 1.2 1 0 0 1 1 1 0 Rifin ECSCR PF15820.5 EAX87331.1 - 0.081 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Adeno_E3_CR2 PF02439.15 EAX87331.1 - 1.3 8.8 14.0 2.4 8.0 14.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 L27_1 PF09058.10 EAX87332.1 - 0.0059 16.6 2.7 0.12 12.4 0.0 2.9 2 1 0 2 2 2 1 L27_1 CREPT PF16566.5 EAX87332.1 - 0.048 13.8 1.0 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX87332.1 - 0.091 12.8 1.1 0.27 11.2 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX87332.1 - 1.1 9.5 7.6 0.47 10.6 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DDE_Tnp_4 PF13359.6 EAX87335.1 - 9.2e-30 103.4 0.0 1.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX87335.1 - 1.2e-11 44.6 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 EAX87335.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.4 1 1 0 1 1 1 0 Plant transposon protein DUF4435 PF14491.6 EAX87335.1 - 0.1 12.5 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) DUF5365 PF17326.2 EAX87337.1 - 0.052 14.0 0.1 0.075 13.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Methyltransf_21 PF05050.12 EAX87340.1 - 3.2e-08 33.8 1.5 4.8e-08 33.2 1.5 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_3 PF01596.17 EAX87340.1 - 0.011 14.9 1.2 0.015 14.4 0.3 1.6 2 0 0 2 2 2 0 O-methyltransferase GDP_Man_Dehyd PF16363.5 EAX87340.1 - 0.014 14.8 0.3 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyoxalase_2 PF12681.7 EAX87340.1 - 0.057 13.4 1.2 0.21 11.6 0.6 2.0 1 1 1 2 2 2 0 Glyoxalase-like domain LAGLIDADG_3 PF14528.6 EAX87340.1 - 0.09 13.1 0.4 0.23 11.8 0.4 1.7 1 0 0 1 1 1 0 LAGLIDADG-like domain VPS9 PF02204.18 EAX87341.1 - 6.8e-06 26.2 1.8 1e-05 25.7 0.2 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Oberon_cc PF16312.5 EAX87341.1 - 0.1 12.5 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of Oberon S10_plectin PF03501.15 EAX87342.1 - 8e-27 93.2 0.0 9.5e-27 92.9 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_5 PF01022.20 EAX87342.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1386 PF07138.11 EAX87343.1 - 0.0024 17.2 1.1 0.026 13.8 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1386) PDZ_1 PF12812.7 EAX87343.1 - 0.098 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ-like domain PSP PF04046.16 EAX87344.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87345.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87348.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87349.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX87351.1 - 3.8e-27 94.1 13.3 3.8e-27 94.1 13.3 3.6 3 0 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX87351.1 - 0.033 13.9 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DNA_pol_B_2 PF03175.13 EAX87352.1 - 5.7e-10 38.7 2.2 3.2e-09 36.2 2.2 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX87352.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 PapD_N PF00345.20 EAX87353.1 - 0.012 15.6 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX87353.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family GPS2_interact PF15784.5 EAX87354.1 - 0.049 14.1 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain EF-hand_4 PF12763.7 EAX87357.1 - 0.51 10.3 7.8 4.7 7.2 0.6 3.9 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Med10 PF09748.9 EAX87357.1 - 1.9 8.5 12.4 0.038 14.0 0.6 4.0 4 0 0 4 4 4 0 Transcription factor subunit Med10 of Mediator complex TMEM52 PF14979.6 EAX87358.1 - 0.058 13.3 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane 52 DUF4452 PF14618.6 EAX87358.1 - 0.65 9.8 5.6 0.84 9.5 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) DUF1388 PF07142.12 EAX87358.1 - 5.4 7.1 9.5 1 9.4 2.1 2.5 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) Ank_2 PF12796.7 EAX87359.1 - 7.1e-35 119.5 23.3 1.1e-07 32.3 0.3 9.3 4 3 6 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87359.1 - 9.9e-28 96.2 13.9 0.00049 20.6 0.0 9.9 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87359.1 - 1.6e-22 77.2 18.8 0.0039 17.6 0.1 12.4 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 EAX87359.1 - 7.8e-20 70.7 19.2 0.00044 20.5 0.0 9.2 8 3 2 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX87359.1 - 6.5e-10 39.0 13.6 0.065 13.7 0.1 9.8 12 0 0 12 12 12 2 Ankyrin repeat Pkinase PF00069.25 EAX87361.1 - 1.8e-60 204.5 0.0 2.1e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87361.1 - 1.2e-31 109.9 0.0 1.6e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87361.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APC1_C PF18122.1 EAX87361.1 - 0.035 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Kdo PF06293.14 EAX87361.1 - 0.043 13.2 0.1 0.064 12.6 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX87361.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 EAX87363.1 - 2.5e-54 181.8 37.3 5.5e-17 62.1 5.7 5.5 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87363.1 - 9.7e-43 144.0 7.0 2.6e-10 40.6 0.0 8.0 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX87363.1 - 2.1e-39 132.3 10.9 1.2e-06 28.7 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EAX87363.1 - 7.5e-37 121.2 15.6 1.4e-05 25.1 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 EAX87363.1 - 6.4e-35 119.0 6.1 2e-34 117.4 6.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX87363.1 - 6.3e-29 99.7 9.3 4.1e-08 33.3 0.0 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) DUF3126 PF11324.8 EAX87363.1 - 0.0071 16.2 0.7 21 5.1 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3126) VBS PF08913.10 EAX87363.1 - 0.025 15.0 0.2 9.8 6.6 0.0 3.3 2 2 2 4 4 4 0 Vinculin Binding Site ThiS-like PF14453.6 EAX87363.1 - 0.043 13.9 1.9 8.5 6.5 0.1 3.7 2 2 2 4 4 4 0 ThiS-like ubiquitin SAB PF04382.13 EAX87363.1 - 0.25 11.5 1.8 37 4.5 0.1 3.8 3 1 1 4 4 4 0 SAB domain PH_8 PF15409.6 EAX87363.1 - 0.26 11.6 0.8 19 5.6 0.0 3.5 2 2 2 4 4 4 0 Pleckstrin homology domain Ras PF00071.22 EAX87364.1 - 8.4e-54 181.5 1.8 1e-53 181.2 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87364.1 - 1.2e-32 112.7 0.4 1.8e-32 112.1 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX87364.1 - 2.4e-15 56.4 0.3 2.9e-15 56.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX87364.1 - 3.4e-07 29.9 0.1 6.3e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX87364.1 - 6.8e-06 25.8 0.3 0.00011 21.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX87364.1 - 2.2e-05 24.5 0.1 5.9e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX87364.1 - 6.8e-05 22.3 0.2 8.4e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EAX87364.1 - 0.00068 19.1 0.1 0.038 13.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 EAX87364.1 - 0.012 15.9 0.1 0.17 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX87364.1 - 0.013 15.0 0.2 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAX87364.1 - 0.015 15.2 0.7 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EAX87364.1 - 0.043 13.6 0.5 0.1 12.4 0.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-MIZ PF02891.20 EAX87365.1 - 0.00029 20.5 1.4 0.00047 19.9 1.4 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Pkinase PF00069.25 EAX87366.1 - 5e-65 219.5 0.5 6.4e-65 219.1 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87366.1 - 4e-44 150.8 0.0 5.2e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87366.1 - 7.9e-08 31.9 0.0 3.6e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX87366.1 - 6e-06 25.3 0.0 1.3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX87366.1 - 0.00043 19.7 0.1 0.00068 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX87366.1 - 0.00092 18.9 0.2 0.01 15.5 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAX87366.1 - 0.0033 16.4 0.4 0.0064 15.5 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX87366.1 - 0.0086 16.0 0.0 0.036 14.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Occludin_ELL PF07303.13 EAX87367.1 - 0.0017 19.0 7.1 0.0023 18.6 7.1 1.2 1 0 0 1 1 1 1 Occludin homology domain zf-C4H2 PF10146.9 EAX87367.1 - 0.0085 16.4 4.5 0.01 16.2 4.5 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein DDE_Tnp_IS240 PF13610.6 EAX87367.1 - 0.016 15.5 1.1 0.018 15.2 1.1 1.2 1 0 0 1 1 1 0 DDE domain Sec2p PF06428.11 EAX87367.1 - 0.016 15.2 11.6 0.32 11.0 3.1 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Syntaxin-6_N PF09177.11 EAX87367.1 - 0.043 14.4 3.1 0.046 14.3 2.6 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Sec8_exocyst PF04048.14 EAX87367.1 - 0.047 13.6 4.0 0.057 13.3 4.0 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain ZapB PF06005.12 EAX87367.1 - 0.14 12.6 11.4 0.38 11.2 11.4 1.8 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 EAX87367.1 - 0.14 12.7 4.8 1.2 9.8 0.5 2.1 1 1 1 2 2 2 0 SlyX Clr5 PF14420.6 EAX87367.1 - 0.25 11.6 4.7 0.32 11.3 1.3 2.2 1 1 1 2 2 2 0 Clr5 domain DUF5595 PF18077.1 EAX87367.1 - 0.29 11.2 8.9 5.9 7.0 8.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5595) YabA PF06156.13 EAX87367.1 - 0.6 10.8 8.5 1 10.0 8.5 1.5 1 1 0 1 1 1 0 Initiation control protein YabA GPS2_interact PF15784.5 EAX87367.1 - 0.76 10.3 11.3 0.56 10.7 1.9 2.3 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain FapA PF03961.13 EAX87367.1 - 1.2 7.7 7.0 1.3 7.5 7.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A M PF02370.16 EAX87367.1 - 1.2 9.9 9.4 6.5 7.7 0.3 2.8 2 0 0 2 2 2 0 M protein repeat TMPIT PF07851.13 EAX87367.1 - 1.3 8.1 5.8 1.4 8.0 5.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein LCD1 PF09798.9 EAX87367.1 - 1.5 7.2 10.6 1.6 7.2 10.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Osmo_CC PF08946.10 EAX87367.1 - 3.3 8.0 9.6 1.3 9.3 0.2 2.7 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DivIC PF04977.15 EAX87367.1 - 4.1 7.2 9.0 1.9 8.3 4.4 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3585 PF12130.8 EAX87368.1 - 0.0086 16.2 3.1 0.12 12.5 3.2 2.0 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain HAMP PF00672.25 EAX87368.1 - 0.024 15.0 0.1 0.052 13.9 0.1 1.6 1 1 0 1 1 1 0 HAMP domain DUF465 PF04325.13 EAX87368.1 - 0.032 14.3 1.7 0.92 9.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Pup PF05639.11 EAX87368.1 - 0.044 14.7 1.0 0.077 13.9 1.0 1.3 1 0 0 1 1 1 0 Pup-like protein FapA PF03961.13 EAX87368.1 - 0.056 12.1 1.4 0.06 11.9 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3740 PF12548.8 EAX87368.1 - 0.067 13.6 1.3 0.1 13.0 1.3 1.3 1 0 0 1 1 1 0 Sulfatase protein Gon7 PF08738.10 EAX87368.1 - 0.084 13.0 3.3 0.17 12.0 3.2 1.7 1 1 0 1 1 1 0 Gon7 family DUF4407 PF14362.6 EAX87368.1 - 0.085 12.2 0.9 0.087 12.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 EAX87368.1 - 0.29 11.1 7.3 0.37 10.7 5.3 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain GalP_UDP_transf PF01087.22 EAX87368.1 - 0.32 11.4 4.5 0.4 11.1 4.5 1.4 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain FlxA PF14282.6 EAX87368.1 - 0.95 9.5 7.8 0.84 9.7 6.8 1.5 1 1 0 1 1 1 0 FlxA-like protein Glyco_hydro_25 PF01183.20 EAX87369.1 - 3.6e-33 115.2 5.1 4.1e-33 115.1 5.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 HTH_Tnp_4 PF13613.6 EAX87370.1 - 0.0032 17.1 2.1 0.018 14.8 1.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease Sugar_tr PF00083.24 EAX87371.1 - 5.9e-57 193.5 15.9 7.7e-57 193.1 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX87371.1 - 2e-26 92.8 33.1 6.3e-19 68.1 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EAX87371.1 - 0.21 11.2 0.0 0.21 11.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) TMEM192 PF14802.6 EAX87371.1 - 0.83 8.7 2.6 2.6 7.1 0.6 2.4 2 0 0 2 2 2 0 TMEM192 family RIX1 PF08167.12 EAX87373.1 - 0.00095 19.0 0.6 8.5 6.1 0.0 5.0 4 2 2 6 6 6 2 rRNA processing/ribosome biogenesis tRNA-synt_2 PF00152.20 EAX87373.1 - 0.0039 16.3 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) UNC45-central PF11701.8 EAX87373.1 - 0.05 13.6 6.0 0.86 9.6 0.1 4.0 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central DUF5063 PF16702.5 EAX87373.1 - 0.088 13.2 0.2 38 4.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5063) PSP PF04046.16 EAX87374.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PH_TFIIH PF08567.11 EAX87376.1 - 0.066 13.6 0.1 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain CPG4 PF15481.6 EAX87376.1 - 0.27 11.9 1.6 1.5 9.5 0.3 2.8 2 1 0 2 2 2 0 Chondroitin proteoglycan 4 zf-RING_2 PF13639.6 EAX87377.1 - 2.9e-12 46.7 13.3 3.8e-12 46.3 10.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX87377.1 - 5e-09 35.9 12.8 5.7e-09 35.7 11.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX87377.1 - 1.3e-08 34.4 5.9 1.3e-08 34.4 5.9 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 EAX87377.1 - 4.5e-08 33.3 8.2 4.5e-08 33.3 8.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAX87377.1 - 1.5e-07 31.2 7.4 1.5e-07 31.2 7.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EAX87377.1 - 3.3e-07 30.1 10.4 8.5e-07 28.7 10.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX87377.1 - 2.2e-06 27.6 4.0 2.2e-06 27.6 4.0 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAX87377.1 - 2.2e-05 24.2 7.3 2.2e-05 24.2 7.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAX87377.1 - 0.0041 17.1 8.9 0.0052 16.8 4.7 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EAX87377.1 - 0.0055 16.9 7.2 0.024 14.8 7.2 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EAX87377.1 - 0.0055 16.3 5.0 0.0055 16.3 5.0 2.2 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EAX87377.1 - 0.02 15.0 9.1 0.041 14.0 9.1 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EAX87377.1 - 0.14 12.1 11.7 0.026 14.4 8.0 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EAX87377.1 - 0.42 10.4 8.0 1 9.2 8.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EAX87377.1 - 1.3 9.3 9.5 4.2 7.6 9.5 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBD PF10416.9 EAX87378.1 - 3.5e-43 146.7 0.7 4.8e-43 146.2 0.7 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PSP PF04046.16 EAX87379.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87380.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX87381.1 - 1.3e-55 188.6 3.8 1.4e-55 188.4 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Meiosis_expr PF15163.6 EAX87382.1 - 0.049 14.3 1.8 0.057 14.1 0.8 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX87382.1 - 1.2 9.1 10.8 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family RNA_pol_Rpb1_5 PF04998.17 EAX87383.1 - 0.14 11.5 2.1 0.3 10.5 1.3 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PSP PF04046.16 EAX87384.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87385.1 - 0.15 12.8 6.1 11 7.2 0.2 3.3 3 1 1 4 4 4 0 TMP repeat VirE2 PF07229.12 EAX87386.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 VirE2 VSP PF03302.13 EAX87387.1 - 0.00025 20.0 1.1 0.00037 19.5 1.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein HEPN_RES_NTD1 PF18870.1 EAX87387.1 - 0.0079 16.4 1.3 2.6 8.2 0.1 3.5 3 0 0 3 3 3 1 HEPN/RES N-terminal domain 1 HTH_19 PF12844.7 EAX87387.1 - 0.012 15.6 0.1 0.057 13.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Lipase_GDSL_lke PF16255.5 EAX87387.1 - 0.021 14.2 0.3 0.048 13.0 0.3 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4690 PF15756.5 EAX87387.1 - 0.026 15.1 0.6 0.026 15.1 0.6 2.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Amnionless PF14828.6 EAX87387.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless BORCS8 PF10167.9 EAX87387.1 - 0.17 11.8 2.1 1.3 8.9 0.0 3.3 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 8 DUF999 PF06198.11 EAX87387.1 - 0.26 11.3 2.2 0.93 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF999) Ferritin PF00210.24 EAX87387.1 - 1.2 9.1 8.6 0.36 10.8 0.1 4.0 4 1 1 5 5 5 0 Ferritin-like domain Podoplanin PF05808.11 EAX87387.1 - 3.2 7.8 6.0 0.27 11.3 0.6 2.0 2 0 0 2 2 2 0 Podoplanin APG17 PF04108.12 EAX87387.1 - 7.7 5.5 8.3 0.98 8.5 0.9 3.1 3 1 0 3 3 3 0 Autophagy protein Apg17 DUF3839 PF12943.7 EAX87388.1 - 7e-158 523.4 14.3 8.8e-158 523.0 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87388.1 - 2.9 8.4 7.4 2.1 8.8 0.6 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX87389.1 - 0.00025 21.5 0.0 0.00061 20.3 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87389.1 - 0.0047 16.8 0.4 0.014 15.2 0.4 1.9 1 1 0 1 1 1 1 KilA-N domain Lectin_legB PF00139.19 EAX87389.1 - 0.019 14.5 0.2 0.064 12.8 0.1 1.7 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX87390.1 - 1.2e-157 522.6 13.6 1.4e-157 522.3 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX87390.1 - 0.025 14.8 0.1 0.08 13.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 Rx_N PF18052.1 EAX87390.1 - 0.077 13.3 0.3 2.2 8.6 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX87390.1 - 0.23 11.9 6.9 0.85 10.1 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX87390.1 - 1.3 9.7 4.7 6.8 7.4 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5398) TMP PF05017.14 EAX87393.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87394.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-bind_6 PF13921.6 EAX87395.1 - 5e-21 74.7 5.8 1.3e-13 50.9 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX87395.1 - 8.1e-19 67.6 4.7 2.2e-14 53.3 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX87395.1 - 2.9e-05 23.9 0.8 4.4e-05 23.3 0.6 1.5 1 1 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX87395.1 - 0.021 15.0 0.9 0.042 14.0 0.9 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Methyltransf_16 PF10294.9 EAX87396.1 - 2e-17 63.5 0.0 2.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EAX87396.1 - 0.00048 19.6 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EAX87396.1 - 0.0098 15.7 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX87396.1 - 0.095 13.4 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EAX87396.1 - 0.1 13.2 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3839 PF12943.7 EAX87397.1 - 2.5e-148 492.1 12.3 3.2e-148 491.7 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87397.1 - 0.011 16.2 0.4 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX87397.1 - 0.033 14.8 2.4 0.73 10.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MitMem_reg PF13012.6 EAX87397.1 - 0.042 14.3 0.8 0.79 10.2 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX87397.1 - 0.19 12.0 3.1 18 5.7 0.1 3.2 3 1 0 3 3 3 0 Tup N-terminal DUF4168 PF13767.6 EAX87397.1 - 1 10.6 4.1 27 6.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) KELK PF15796.5 EAX87397.1 - 1.1 9.8 5.9 1.9 9.0 1.1 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX87399.1 - 0.038 14.5 4.6 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87400.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX87402.1 - 1.2e-126 421.1 5.1 1.3e-126 421.0 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX87402.1 - 0.044 13.3 0.5 0.076 12.5 0.2 1.4 1 1 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX87402.1 - 0.27 11.9 1.5 0.54 10.9 0.2 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5398) PTR PF12789.7 EAX87404.1 - 1.8e-52 175.2 33.2 1.7e-34 117.7 16.1 4.7 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX87404.1 - 0.085 12.6 0.1 0.31 10.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX87405.1 - 0.033 14.7 0.8 0.061 13.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ank_2 PF12796.7 EAX87406.1 - 1.9e-64 214.2 5.1 2.2e-15 57.0 1.5 7.5 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87406.1 - 1.9e-58 194.1 6.2 1.1e-10 41.8 0.0 10.2 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87406.1 - 6.6e-56 179.7 6.3 1.2e-05 25.3 0.0 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EAX87406.1 - 1.1e-47 159.4 8.2 2e-07 31.1 0.0 9.4 5 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX87406.1 - 1e-46 155.4 3.4 2.7e-06 27.6 0.1 12.4 12 0 0 12 12 12 8 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX87406.1 - 5.5e-09 35.8 11.8 1.1e-08 34.7 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX87406.1 - 1.5e-05 24.7 12.1 4.7e-05 23.2 12.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAX87406.1 - 0.0013 19.0 13.4 0.0025 18.1 13.4 1.5 1 0 0 1 1 1 1 Ring finger domain UDPG_MGDP_dh_C PF03720.15 EAX87406.1 - 0.044 14.2 0.1 0.18 12.2 0.1 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain zf-C3HC4_2 PF13923.6 EAX87406.1 - 4.4 7.2 15.9 8.7 6.3 15.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F_actin_cap_B PF01115.17 EAX87407.1 - 2e-68 230.6 0.0 2.2e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF4973 PF16343.5 EAX87407.1 - 0.011 15.8 0.1 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) Snf7 PF03357.21 EAX87408.1 - 1.8e-35 122.1 18.8 2.1e-35 121.8 18.8 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 EAX87408.1 - 0.014 15.3 1.3 0.014 15.3 1.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit Fzo_mitofusin PF04799.13 EAX87408.1 - 0.034 13.7 6.2 0.17 11.4 0.7 2.2 2 0 0 2 2 2 0 fzo-like conserved region CHASE7 PF17151.4 EAX87408.1 - 0.054 13.1 1.2 0.094 12.3 1.2 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain T3SS_basalb_I PF17001.5 EAX87408.1 - 0.11 13.1 9.0 2.7 8.6 3.9 2.2 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI ABC_tran_CTD PF16326.5 EAX87408.1 - 0.12 12.6 0.4 0.12 12.6 0.4 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF948 PF06103.11 EAX87408.1 - 0.15 12.3 8.1 1.1 9.6 3.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EAX87408.1 - 0.3 11.7 4.6 0.62 10.7 2.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal zf-C2H2_aberr PF17017.5 EAX87408.1 - 0.36 11.0 3.5 0.52 10.4 3.0 1.3 1 1 0 1 1 1 0 Aberrant zinc-finger Allexi_40kDa PF05549.11 EAX87408.1 - 4 6.9 5.3 1.1 8.7 0.5 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1690 PF07956.11 EAX87408.1 - 8.2 6.8 8.7 1.6 9.2 1.9 2.3 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) K-box PF01486.17 EAX87408.1 - 9.3 6.5 11.5 2.4 8.4 0.3 3.4 2 2 1 3 3 3 0 K-box region WD40 PF00400.32 EAX87410.1 - 1.6e-22 79.4 13.9 9.7e-07 29.4 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX87410.1 - 1.2e-07 32.0 0.0 0.31 11.3 0.0 5.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX87410.1 - 0.00049 19.2 0.8 0.081 11.9 0.3 2.9 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EAX87410.1 - 0.00054 18.4 0.0 0.0007 18.0 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 EAX87410.1 - 0.0015 18.4 0.1 0.4 10.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAX87410.1 - 0.0073 15.7 0.4 0.11 11.8 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 EAX87410.1 - 0.023 14.3 0.1 0.039 13.5 0.1 1.6 1 1 0 1 1 1 0 PQQ-like domain DDE_1 PF03184.19 EAX87412.1 - 1.5e-16 60.5 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TMP PF05017.14 EAX87413.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87414.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Macoilin PF09726.9 EAX87415.1 - 1.3 7.5 29.9 1.9 6.9 29.9 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_64 PF09258.10 EAX87416.1 - 6.3e-47 159.9 0.1 7.6e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 EAX87416.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Methyltransf_23 PF13489.6 EAX87417.1 - 1.3e-16 60.9 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX87417.1 - 1.8e-15 57.5 0.0 3.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX87417.1 - 7.1e-14 52.3 0.0 1.4e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX87417.1 - 8.9e-14 51.5 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX87417.1 - 3.1e-12 47.0 0.0 6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EAX87417.1 - 5.6e-08 32.7 0.0 7.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EAX87417.1 - 7.6e-08 32.1 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 EAX87417.1 - 5e-07 29.2 0.0 7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 EAX87417.1 - 1.7e-06 27.6 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 EAX87417.1 - 4.6e-05 22.9 0.0 5.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 EAX87417.1 - 7.6e-05 21.4 0.0 9.7e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EAX87417.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EAX87417.1 - 0.0019 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MetW PF07021.12 EAX87417.1 - 0.0055 16.3 0.0 0.0077 15.8 0.0 1.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EAX87417.1 - 0.0096 14.9 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NNMT_PNMT_TEMT PF01234.17 EAX87417.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Cons_hypoth95 PF03602.15 EAX87417.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 EAX87417.1 - 0.05 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EAX87417.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0242 PF06785.11 EAX87418.1 - 0.041 14.0 12.9 0.055 13.6 12.9 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 EAX87418.1 - 0.33 11.2 8.6 0.73 10.1 8.6 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 YtxH PF12732.7 EAX87418.1 - 0.43 11.1 1.6 5.6 7.6 1.6 2.5 1 1 0 1 1 1 0 YtxH-like protein ABC2_membrane_3 PF12698.7 EAX87418.1 - 2.6 7.1 6.6 3.2 6.8 6.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4665 PF15679.5 EAX87418.1 - 4.6 7.9 9.3 0.27 11.9 2.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) Ank_2 PF12796.7 EAX87419.1 - 1.3e-65 218.0 19.3 3.4e-13 50.0 0.6 9.2 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87419.1 - 2.3e-51 171.6 7.3 1.2e-10 41.7 0.0 11.5 8 3 4 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87419.1 - 3e-47 153.1 16.1 0.0091 16.4 0.0 16.5 16 1 1 17 17 17 11 Ankyrin repeat Ank_5 PF13857.6 EAX87419.1 - 9.6e-44 146.9 10.7 1.9e-05 24.9 0.0 12.7 6 4 7 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX87419.1 - 5.4e-37 124.6 10.8 0.00066 20.0 0.1 13.7 14 0 0 14 14 14 8 Ankyrin repeat DUF3447 PF11929.8 EAX87419.1 - 1.5e-11 44.1 0.3 1.5e-11 44.1 0.3 6.2 5 3 2 7 7 7 2 Domain of unknown function (DUF3447) PSP PF04046.16 EAX87420.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87421.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87422.1 - 0.044 14.2 0.2 0.089 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Meiosis_expr PF15163.6 EAX87425.1 - 0.059 14.0 0.5 0.11 13.2 0.2 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX87425.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Gly_rich PF12810.7 EAX87428.1 - 3.3e-16 60.0 10.1 3.7e-16 59.8 10.1 1.0 1 0 0 1 1 1 1 Glycine rich protein SHMT PF00464.19 EAX87429.1 - 0.0076 14.9 0.1 0.0092 14.6 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Pkinase PF00069.25 EAX87431.1 - 1.2e-50 172.4 0.0 1.6e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87431.1 - 2.3e-29 102.5 0.0 2.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87431.1 - 4.1e-05 23.0 0.0 8e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX87431.1 - 7.5e-05 22.2 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX87431.1 - 0.00092 18.3 0.1 0.0078 15.2 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAX87431.1 - 0.00093 18.8 0.2 0.0014 18.3 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EAX87431.1 - 0.019 14.1 0.0 0.13 11.2 0.1 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 Amidase02_C PF12123.8 EAX87432.1 - 0.0099 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87433.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_D5 PF03288.16 EAX87434.1 - 2.6e-05 24.6 2.6 0.00015 22.2 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX87435.1 - 2e-61 206.1 8.0 2.2e-61 205.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX87435.1 - 0.037 14.2 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX87437.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87437.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87437.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87437.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87437.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87437.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87437.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87437.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87437.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87437.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87437.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX87437.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX87438.1 - 3.7e-42 142.7 0.6 7.3e-42 141.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX87438.1 - 0.017 15.7 0.5 0.05 14.2 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX87439.1 - 3.6e-155 514.5 10.3 4.6e-155 514.1 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX87439.1 - 0.15 12.3 0.9 3.5 8.0 0.0 3.2 3 1 1 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX87439.1 - 0.39 11.2 4.0 5.5 7.5 0.1 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX87439.1 - 1.5 9.4 5.6 0.48 11.0 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX87439.1 - 3.2 8.1 7.3 11 6.4 0.1 3.9 4 2 0 4 4 4 0 Tup N-terminal PTR PF12789.7 EAX87441.1 - 0.023 14.7 1.9 0.023 14.7 1.9 2.6 3 1 0 3 3 3 0 Phage tail repeat like BRO1 PF03097.18 EAX87441.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF4795 PF16043.5 EAX87441.1 - 0.08 12.5 5.1 0.23 11.1 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX87441.1 - 1.3 9.4 7.0 3.4 8.1 1.1 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat Ank_2 PF12796.7 EAX87442.1 - 1.6e-45 153.6 0.7 1.8e-20 73.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87442.1 - 9.3e-34 115.4 0.1 3.1e-11 43.5 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX87442.1 - 3.1e-29 100.1 0.1 4.6e-06 26.8 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX87442.1 - 8.4e-28 96.1 1.2 2.7e-09 37.1 0.0 5.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87442.1 - 2.4e-24 82.8 0.0 0.00079 19.7 0.0 6.3 7 0 0 7 7 6 5 Ankyrin repeat HALZ PF02183.18 EAX87442.1 - 0.0031 17.7 1.7 0.0065 16.7 1.7 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper Peptidase_Mx1 PF15890.5 EAX87442.1 - 0.0041 16.6 0.1 0.0065 15.9 0.1 1.3 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase ZapB PF06005.12 EAX87442.1 - 0.011 16.1 4.8 0.022 15.2 4.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TMCO5 PF14992.6 EAX87442.1 - 0.021 14.4 2.5 0.029 14.0 2.5 1.2 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 EAX87442.1 - 0.074 12.8 1.7 0.14 11.9 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator ERM PF00769.19 EAX87442.1 - 0.081 12.7 4.3 0.13 12.1 4.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EAX87442.1 - 0.09 12.1 1.2 0.13 11.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 EAX87442.1 - 0.23 12.1 2.8 0.42 11.3 2.8 1.3 1 0 0 1 1 1 0 SlyX HemX PF04375.14 EAX87443.1 - 0.0018 17.7 7.3 0.0023 17.3 7.3 1.4 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase GAS PF13851.6 EAX87443.1 - 0.0024 17.3 22.8 0.0033 16.8 22.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding 23S_rRNA_IVP PF05635.11 EAX87443.1 - 0.0058 16.9 10.3 0.019 15.3 4.3 2.0 1 1 1 2 2 2 1 23S rRNA-intervening sequence protein SIKE PF05769.11 EAX87443.1 - 0.0065 16.4 14.7 0.064 13.2 1.1 2.2 2 0 0 2 2 2 2 SIKE family DUF2009 PF09418.10 EAX87443.1 - 0.01 15.0 6.1 0.012 14.7 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) HAD_SAK_1 PF10307.9 EAX87443.1 - 0.011 15.6 1.3 0.011 15.6 1.3 2.0 1 1 1 2 2 2 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins ZapB PF06005.12 EAX87443.1 - 0.013 15.9 12.5 0.013 15.9 12.5 3.1 1 1 2 3 3 3 0 Cell division protein ZapB FliS PF02561.14 EAX87443.1 - 0.025 14.9 5.6 0.038 14.3 5.6 1.3 1 0 0 1 1 1 0 Flagellar protein FliS DUF4407 PF14362.6 EAX87443.1 - 0.031 13.7 11.3 0.042 13.2 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EAX87443.1 - 0.035 13.0 17.3 0.059 12.2 17.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EAX87443.1 - 0.043 13.3 20.5 0.033 13.7 18.6 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 EAX87443.1 - 0.047 13.9 22.0 0.32 11.2 22.2 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LXG PF04740.12 EAX87443.1 - 0.049 13.4 14.3 0.039 13.7 11.9 1.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily CENP-O PF09496.10 EAX87443.1 - 0.057 13.4 7.2 0.077 13.0 7.2 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component APG6_N PF17675.1 EAX87443.1 - 0.066 13.7 22.6 0.023 15.2 19.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region OEP PF02321.18 EAX87443.1 - 0.078 12.8 9.0 0.11 12.3 9.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4922 PF16269.5 EAX87443.1 - 0.079 12.7 2.6 0.1 12.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) Sec20 PF03908.13 EAX87443.1 - 0.087 12.8 9.7 0.081 12.9 6.5 2.1 1 1 0 2 2 2 0 Sec20 Syntaxin PF00804.25 EAX87443.1 - 0.1 12.3 18.8 0.083 12.6 13.5 2.0 1 1 1 2 2 2 0 Syntaxin FliJ PF02050.16 EAX87443.1 - 0.12 12.6 21.9 0.13 12.5 6.9 2.6 1 1 2 3 3 3 0 Flagellar FliJ protein TSNAXIP1_N PF15739.5 EAX87443.1 - 0.14 12.5 17.3 0.088 13.2 10.3 2.4 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus CREPT PF16566.5 EAX87443.1 - 0.14 12.3 18.2 0.41 10.8 18.0 1.9 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5401 PF17380.2 EAX87443.1 - 0.17 9.9 20.7 0.2 9.7 20.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Fez1 PF06818.15 EAX87443.1 - 0.18 12.3 19.9 1.3 9.5 19.1 1.9 1 1 1 2 2 2 0 Fez1 DDE_Tnp_IS66 PF03050.14 EAX87443.1 - 0.18 11.3 6.8 0.23 10.9 6.8 1.1 1 0 0 1 1 1 0 Transposase IS66 family FliT PF05400.13 EAX87443.1 - 0.25 12.2 13.7 0.49 11.2 9.0 2.5 1 1 1 2 2 2 0 Flagellar protein FliT VIT1 PF01988.19 EAX87443.1 - 0.28 11.0 6.6 0.37 10.6 5.7 1.6 1 1 0 1 1 1 0 VIT family Seryl_tRNA_N PF02403.22 EAX87443.1 - 0.3 11.3 22.3 0.46 10.7 19.5 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 EAX87443.1 - 0.32 11.6 14.6 0.49 11.0 11.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CdvA PF18822.1 EAX87443.1 - 0.33 10.8 19.1 5.4 6.9 15.3 3.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain V_ATPase_I PF01496.19 EAX87443.1 - 0.42 8.5 11.7 0.47 8.3 11.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 EAX87443.1 - 0.43 9.9 14.5 0.55 9.5 14.5 1.1 1 0 0 1 1 1 0 FAM76 protein LETM1 PF07766.13 EAX87443.1 - 0.45 9.8 11.2 0.54 9.5 11.2 1.1 1 0 0 1 1 1 0 LETM1-like protein Exonuc_VII_L PF02601.15 EAX87443.1 - 0.46 10.0 12.3 0.56 9.7 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 EAX87443.1 - 0.49 10.9 10.1 1.1 9.8 3.2 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB BLOC1_2 PF10046.9 EAX87443.1 - 0.61 10.4 19.8 5.6 7.3 15.1 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 EAX87443.1 - 0.66 10.7 16.4 0.74 10.6 13.3 2.2 1 1 1 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.11 EAX87443.1 - 0.68 9.7 20.6 1.2 8.9 20.6 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 ApoO PF09769.9 EAX87443.1 - 0.86 9.6 6.3 1.8 8.5 5.2 2.1 2 1 0 2 2 1 0 Apolipoprotein O DUF3450 PF11932.8 EAX87443.1 - 0.93 8.7 19.3 2 7.7 19.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DHR10 PF18595.1 EAX87443.1 - 1.2 9.2 22.8 2.6 8.1 10.2 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Med21 PF11221.8 EAX87443.1 - 1.3 9.2 18.3 0.078 13.2 8.5 2.3 1 1 1 2 2 2 0 Subunit 21 of Mediator complex YabA PF06156.13 EAX87443.1 - 1.4 9.6 17.8 0.18 12.4 6.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CENP-K PF11802.8 EAX87443.1 - 1.5 8.4 20.7 2.6 7.5 20.7 1.4 1 1 0 1 1 1 0 Centromere-associated protein K IFT57 PF10498.9 EAX87443.1 - 1.5 7.7 19.9 2.5 7.0 19.8 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Nefa_Nip30_N PF10187.9 EAX87443.1 - 1.7 9.1 18.3 3 8.2 17.9 1.6 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DASH_Dam1 PF08653.10 EAX87443.1 - 1.9 8.4 5.7 39 4.1 1.3 3.7 2 1 2 4 4 4 0 DASH complex subunit Dam1 DUF2312 PF10073.9 EAX87443.1 - 2.2 8.0 13.7 0.66 9.7 10.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) CorA PF01544.18 EAX87443.1 - 2.5 7.4 7.6 3.1 7.0 7.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-H PF05837.12 EAX87443.1 - 2.7 8.5 20.1 2.8 8.4 10.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2443 PF10398.9 EAX87443.1 - 2.7 8.1 13.5 0.49 10.5 1.8 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2443) DUF948 PF06103.11 EAX87443.1 - 2.9 8.2 8.8 3 8.2 4.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EAX87443.1 - 3.2 7.8 14.1 2.4 8.2 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAX87443.1 - 4.6 7.4 20.1 8.4 6.6 13.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 EAX87443.1 - 4.6 7.6 23.6 12 6.2 23.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 EAX87443.1 - 4.8 7.7 21.4 3.5 8.2 6.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 EAX87443.1 - 5.4 6.5 16.2 4.7 6.7 8.0 2.2 1 1 1 2 2 2 0 fzo-like conserved region PCRF PF03462.18 EAX87443.1 - 5.5 6.8 14.7 17 5.2 14.7 1.7 1 1 0 1 1 1 0 PCRF domain COG2 PF06148.11 EAX87443.1 - 5.8 7.0 15.1 3.4 7.7 1.1 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 EAX87443.1 - 6.2 6.9 25.5 20 5.2 12.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 EAX87443.1 - 6.3 5.3 20.0 14 4.1 20.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 EAX87443.1 - 6.5 7.4 21.4 32 5.2 20.7 2.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4094 PF13334.6 EAX87443.1 - 6.9 7.2 13.4 1.5 9.3 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Retrotrans_gag PF03732.17 EAX87443.1 - 7.8 6.9 9.3 14 6.0 6.0 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein ADIP PF11559.8 EAX87443.1 - 8.5 6.4 26.0 0.59 10.2 11.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3447 PF11929.8 EAX87444.1 - 4.8e-31 106.6 7.0 4.8e-31 106.6 7.0 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX87444.1 - 1e-23 83.4 0.8 1.4e-10 41.5 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87444.1 - 5.8e-17 62.1 6.6 3.4e-14 53.2 0.7 3.8 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87444.1 - 8.3e-17 61.0 0.4 3e-08 33.8 0.1 3.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX87444.1 - 1.4e-13 50.6 0.2 6.4e-05 23.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX87444.1 - 4.7e-13 48.1 2.2 0.00036 20.8 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat LRR_5 PF13306.6 EAX87445.1 - 2.5e-81 270.0 58.3 1.2e-32 112.6 4.8 4.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87445.1 - 7.7e-18 64.0 0.4 0.00052 19.7 0.1 7.5 2 1 7 9 9 9 7 Leucine rich repeat DUF4690 PF15756.5 EAX87445.1 - 0.0022 18.5 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EAX87445.1 - 0.024 14.7 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Podoplanin LRR_4 PF12799.7 EAX87445.1 - 0.03 14.8 13.2 5.7 7.5 0.1 7.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Sigma_reg_N PF13800.6 EAX87445.1 - 0.039 14.3 0.4 0.1 12.9 0.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal UL45 PF05473.12 EAX87445.1 - 0.057 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like EphA2_TM PF14575.6 EAX87445.1 - 0.073 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 EAX87445.1 - 0.18 11.3 1.4 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Ribosomal_S7e PF01251.18 EAX87446.1 - 5.1e-40 137.2 0.2 5.5e-40 137.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TMP PF05017.14 EAX87448.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87449.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4448 PF14610.6 EAX87451.1 - 3.8e-05 23.5 1.1 5.3e-05 23.1 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Orf78 PF06024.12 EAX87451.1 - 0.00074 19.8 0.3 0.001 19.3 0.3 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF3377 PF11857.8 EAX87451.1 - 0.005 16.7 4.0 0.005 16.7 4.0 2.0 1 1 2 3 3 3 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 EAX87451.1 - 0.0052 16.7 9.7 0.012 15.5 9.7 1.7 1 1 0 1 1 1 1 TMEM154 protein family EVI2A PF05399.11 EAX87451.1 - 0.0083 15.7 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Rax2 PF12768.7 EAX87451.1 - 0.013 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RIFIN PF02009.16 EAX87451.1 - 0.016 15.1 0.9 0.019 14.9 0.9 1.1 1 0 0 1 1 1 0 Rifin ODV-E18 PF10717.9 EAX87451.1 - 0.022 14.6 1.9 0.022 14.6 1.9 1.5 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5383 PF17355.2 EAX87451.1 - 0.03 14.7 0.7 0.051 13.9 0.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5383) EphA2_TM PF14575.6 EAX87451.1 - 0.031 15.2 1.2 0.059 14.3 0.4 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Oxidored_q2 PF00420.24 EAX87451.1 - 0.031 13.9 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF872 PF05915.12 EAX87451.1 - 0.046 13.9 0.1 0.062 13.5 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Sigma_reg_N PF13800.6 EAX87451.1 - 0.18 12.1 2.2 0.16 12.3 0.8 1.7 1 1 1 2 2 2 0 Sigma factor regulator N-terminal AJAP1_PANP_C PF15298.6 EAX87451.1 - 0.35 11.1 4.8 0.48 10.6 4.9 1.3 1 1 0 1 1 1 0 AJAP1/PANP C-terminus DUF3169 PF11368.8 EAX87451.1 - 1.3 8.5 4.9 0.16 11.5 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Vpu PF00558.19 EAX87451.1 - 1.8 8.4 8.8 0.58 10.0 0.6 2.2 2 0 0 2 2 2 0 Vpu protein DUF563 PF04577.14 EAX87452.1 - 8.7e-22 78.3 0.0 1.1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Gly-zipper_Omp PF13488.6 EAX87453.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX87453.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX87453.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ARA70 PF12489.8 EAX87454.1 - 0.11 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Nuclear coactivator Y_phosphatase2 PF03162.13 EAX87455.1 - 0.015 14.9 0.3 0.026 14.1 0.3 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX87455.1 - 0.04 13.9 0.3 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX87455.1 - 0.077 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 PAS_9 PF13426.7 EAX87456.1 - 1.4e-05 25.3 0.1 2.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 EAX87456.1 - 0.0068 15.9 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF3481 PF11980.8 EAX87457.1 - 0.0039 16.9 0.7 0.0056 16.4 0.7 1.2 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein Tweety PF04906.13 EAX87457.1 - 0.049 12.3 1.0 0.073 11.7 1.0 1.2 1 0 0 1 1 1 0 Tweety TMEM132D_C PF15706.5 EAX87457.1 - 0.45 10.3 2.2 0.51 10.2 0.1 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Hydrolase_6 PF13344.6 EAX87460.1 - 3.3e-19 68.9 0.0 6.3e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX87460.1 - 1.4e-17 63.5 0.0 2.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAX87460.1 - 1.9e-09 38.2 0.6 0.0038 17.5 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAX87460.1 - 5.5e-09 36.4 0.1 5.3e-06 26.6 0.0 3.3 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EAX87460.1 - 0.00068 19.3 0.0 0.077 12.6 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase TMP PF05017.14 EAX87461.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX87462.1 - 7.2e-157 520.0 11.7 9e-157 519.7 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX87462.1 - 2.5 8.7 5.6 1.2 9.8 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX87462.1 - 6.5 7.3 6.9 5.1 7.6 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX87463.1 - 2.1e-58 196.3 5.8 2.4e-58 196.1 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX87465.1 - 9.5e-07 28.5 2.0 9.5e-07 28.5 2.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87465.1 - 3.4e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87465.1 - 4.2e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87465.1 - 0.00015 21.8 3.3 0.00035 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87465.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX87465.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX87465.1 - 0.0021 17.9 0.9 0.0086 15.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX87465.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX87465.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX87465.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX87465.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX87465.1 - 0.24 11.8 3.2 0.73 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX87465.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX87466.1 - 8.3e-38 128.7 1.6 8.3e-38 128.7 1.6 2.4 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX87466.1 - 0.0092 16.6 0.3 0.047 14.3 0.0 2.2 2 0 0 2 2 2 1 Parathyroid hormone family T5orf172 PF10544.9 EAX87467.1 - 2.4e-07 31.2 0.3 4.9e-07 30.2 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX87467.1 - 0.11 13.2 0.3 0.3 11.8 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Trypan_PARP PF05887.11 EAX87468.1 - 0.04 13.9 7.7 0.062 13.3 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX87468.1 - 3.5 8.1 4.5 4.9 7.6 4.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX87469.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX87469.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain VPS9 PF02204.18 EAX87471.1 - 0.0002 21.5 1.2 0.0014 18.8 0.5 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Tubulin PF00091.25 EAX87472.1 - 2.1e-63 214.1 0.0 2.6e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EAX87472.1 - 7e-06 26.3 0.0 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAX87472.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAX87472.1 - 0.034 13.3 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Tubulin_C PF03953.17 EAX87473.1 - 4.2e-23 81.9 0.0 6.7e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 Tubulin C-terminal domain VPS9 PF02204.18 EAX87474.1 - 0.014 15.6 0.3 0.055 13.7 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain EMP70 PF02990.16 EAX87475.1 - 1.7e-33 116.1 30.0 2.5e-33 115.5 30.0 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2684 PF10885.8 EAX87475.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2684) DUF4149 PF13664.6 EAX87475.1 - 6.3 7.2 17.0 0.18 12.1 4.0 3.2 2 2 0 3 3 3 0 Domain of unknown function (DUF4149) DUF3447 PF11929.8 EAX87476.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87476.1 - 0.001 19.6 0.1 0.072 13.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87476.1 - 0.018 15.6 0.2 73 4.1 0.0 4.1 4 1 0 4 4 4 0 Ankyrin repeats (many copies) PSP PF04046.16 EAX87477.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX87478.1 - 0.083 13.4 0.8 0.18 12.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX87478.1 - 0.62 10.1 3.6 12 6.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX87479.1 - 3.3e-151 501.5 11.0 4.1e-151 501.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87479.1 - 0.037 14.5 0.7 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX87479.1 - 0.056 13.7 0.7 15 6.0 0.1 3.5 3 1 1 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX87479.1 - 0.1 13.1 1.6 0.44 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Suc_Fer-like PF06999.12 EAX87479.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like KELK PF15796.5 EAX87479.1 - 0.14 12.6 4.7 1.9 9.0 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2207 PF09972.9 EAX87480.1 - 9.5e-05 21.3 1.3 0.00013 20.9 1.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Hpr_kinase_C PF07475.12 EAX87480.1 - 0.12 11.9 1.8 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain CRPA PF05745.11 EAX87480.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.4 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FixH PF05751.11 EAX87480.1 - 0.55 10.2 1.9 17 5.4 1.2 2.2 2 0 0 2 2 2 0 FixH ODV-E18 PF10717.9 EAX87480.1 - 0.74 9.7 3.4 0.62 10.0 1.7 1.7 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 FeoB_associated PF12669.7 EAX87480.1 - 1 9.8 6.9 2.3 8.7 6.9 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4330 PF14221.6 EAX87480.1 - 9.3 6.4 9.2 2.1 8.5 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4330) PSP PF04046.16 EAX87481.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87482.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX87484.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX87487.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX87487.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX87487.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX87488.1 - 6.1e-05 22.6 2.4 6.1e-05 22.6 2.4 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX87488.1 - 0.0041 17.1 0.1 0.0094 16.0 0.1 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX87488.1 - 0.0073 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX87488.1 - 0.065 12.5 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4795 PF16043.5 EAX87489.1 - 0.1 12.2 0.3 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX87490.1 - 1.9e-52 175.1 33.7 1.3e-32 111.6 14.6 5.0 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX87490.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX87491.1 - 0.075 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX87492.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87493.1 - 0.054 13.4 0.6 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP DUF4107 PF13389.6 EAX87497.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PHD PF00628.29 EAX87499.1 - 6.9e-07 29.1 10.4 1e-06 28.5 10.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAX87499.1 - 0.0017 17.9 5.6 0.0026 17.3 5.6 1.3 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 EAX87499.1 - 0.07 13.3 4.4 0.11 12.8 4.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger GIT1_C PF12205.8 EAX87499.1 - 0.14 12.3 1.7 1.7 8.7 0.5 2.3 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term zf-CW PF07496.15 EAX87499.1 - 0.14 12.2 3.6 0.3 11.1 3.6 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.22 EAX87499.1 - 1.1 9.2 10.0 0.4 10.6 5.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 EAX87500.1 - 5.8e-35 119.7 0.2 5.7e-14 52.5 0.0 5.4 3 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87500.1 - 9e-29 99.5 0.4 1.7e-06 28.5 0.0 8.8 7 2 4 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87500.1 - 1.4e-25 86.6 0.0 0.0002 21.5 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EAX87500.1 - 1.3e-22 79.5 0.3 1.2e-05 25.4 0.0 8.0 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX87500.1 - 5.1e-14 52.0 0.0 0.00085 19.7 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeat DUF2312 PF10073.9 EAX87500.1 - 0.21 11.3 2.1 0.66 9.7 2.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3826 PF12875.7 EAX87500.1 - 0.6 10.2 5.8 0.17 12.0 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) ARA70 PF12489.8 EAX87501.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator PTR PF12789.7 EAX87502.1 - 1.8e-10 40.7 22.7 2.7e-08 33.7 4.6 4.9 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX87502.1 - 0.0016 18.0 14.0 0.039 13.6 2.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX87502.1 - 0.46 11.0 9.4 25 5.5 0.1 4.1 4 1 0 4 4 4 0 YmaF family Phage_fiber PF03335.13 EAX87502.1 - 9.2 6.7 24.5 4.7 7.7 1.1 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX87503.1 - 0.081 13.4 0.5 0.18 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX87504.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX87506.1 - 3.7e-52 174.9 20.6 1e-12 48.4 0.1 6.2 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87506.1 - 7.6e-50 165.3 22.4 8.1e-08 32.4 0.3 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 EAX87506.1 - 2.9e-46 155.2 21.3 1.2e-09 38.5 0.0 9.7 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87506.1 - 1.7e-40 132.3 19.0 0.00012 22.2 0.0 10.9 11 1 1 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 EAX87506.1 - 2.3e-40 136.1 16.8 4.3e-11 42.8 0.1 6.7 4 3 3 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX87506.1 - 1.2e-35 121.3 8.0 1.2e-35 121.3 8.0 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Peptidase_M16 PF00675.20 EAX87506.1 - 0.014 15.3 0.3 1.5 8.7 0.0 3.1 3 1 0 3 3 3 0 Insulinase (Peptidase family M16) RL PF17797.1 EAX87506.1 - 0.96 9.4 6.2 16 5.6 0.2 4.5 5 0 0 5 5 5 0 RL domain TMF_DNA_bd PF12329.8 EAX87507.1 - 0.011 15.7 6.2 0.011 15.7 6.2 10.1 9 2 1 11 11 11 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 EAX87507.1 - 0.014 15.6 7.9 0.014 15.6 7.9 7.1 6 2 1 7 7 7 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EAX87507.1 - 3.1 7.8 109.8 0.074 13.1 14.1 6.8 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 z-alpha PF02295.17 EAX87508.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain B3 PF02362.21 EAX87508.1 - 0.21 11.5 1.1 11 6.0 0.1 2.4 1 1 1 2 2 2 0 B3 DNA binding domain Spo12 PF05032.12 EAX87509.1 - 0.53 10.2 8.3 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF883 PF05957.13 EAX87510.1 - 0.022 15.4 8.8 0.022 15.4 8.8 13.1 3 3 9 14 14 14 0 Bacterial protein of unknown function (DUF883) FAM184 PF15665.5 EAX87510.1 - 0.28 10.9 239.7 0.059 13.1 32.0 8.4 1 1 6 7 7 7 0 Family with sequence similarity 184, A and B IL15 PF02372.15 EAX87511.1 - 0.047 13.7 3.0 1.8 8.6 0.1 3.2 3 0 0 3 3 3 0 Interleukin 15 AI-2E_transport PF01594.16 EAX87511.1 - 0.41 9.8 4.0 0.25 10.5 1.5 1.9 2 0 0 2 2 2 0 AI-2E family transporter Ank_2 PF12796.7 EAX87512.1 - 1.6e-46 156.8 3.8 2.4e-14 53.7 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87512.1 - 1.2e-34 118.2 1.3 3.1e-07 30.8 0.2 6.7 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX87512.1 - 1.4e-32 110.7 0.4 0.00061 20.1 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX87512.1 - 1.7e-30 104.7 0.8 5.7e-09 36.1 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87512.1 - 9.2e-30 99.4 2.0 0.00021 21.4 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat TMF_TATA_bd PF12325.8 EAX87512.1 - 0.0028 17.9 12.8 0.059 13.6 5.4 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EAX87512.1 - 0.025 15.5 7.3 0.025 15.5 7.3 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain PTPA PF03095.15 EAX87512.1 - 0.043 13.3 2.8 0.074 12.5 2.8 1.4 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein HEM4 PF02602.15 EAX87512.1 - 0.074 12.4 0.0 0.29 10.4 0.0 1.8 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD DUF4404 PF14357.6 EAX87512.1 - 0.093 13.4 3.1 0.3 11.8 3.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ATG16 PF08614.11 EAX87512.1 - 0.33 11.2 12.9 0.65 10.2 12.8 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EAX87512.1 - 0.34 10.1 16.9 0.56 9.4 10.4 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ERM PF00769.19 EAX87512.1 - 0.59 9.9 11.2 0.92 9.3 11.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EAX87512.1 - 0.63 9.3 9.9 0.37 10.1 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) NRBF2 PF08961.10 EAX87512.1 - 3.5 7.2 9.9 0.65 9.6 4.8 2.1 1 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 EAX87512.1 - 4.6 7.8 20.4 31 5.1 14.0 3.3 1 1 1 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 EAX87512.1 - 7.5 7.0 17.1 0.35 11.3 2.4 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EAX87512.1 - 9.2 7.0 16.2 15 6.3 7.5 3.0 1 1 2 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 EAX87513.1 - 0.0037 17.8 6.2 0.0052 17.3 6.2 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Macoilin PF09726.9 EAX87513.1 - 0.0086 14.7 9.6 0.0094 14.6 9.6 1.1 1 0 0 1 1 1 1 Macoilin family HAP1_N PF04849.13 EAX87513.1 - 0.025 13.8 10.9 0.041 13.1 10.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TMF_TATA_bd PF12325.8 EAX87513.1 - 0.12 12.6 11.5 0.35 11.1 11.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EAX87513.1 - 0.15 12.2 17.0 0.23 11.7 17.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EAX87513.1 - 0.18 12.3 23.8 0.58 10.6 10.2 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Uso1_p115_C PF04871.13 EAX87513.1 - 0.43 10.9 14.2 0.86 10.0 14.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LMBR1 PF04791.16 EAX87513.1 - 0.71 8.7 8.9 0.81 8.5 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EAX87513.1 - 1.7 7.9 13.1 2.4 7.4 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 EAX87513.1 - 5.5 7.7 6.4 54 4.5 6.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Amidase02_C PF12123.8 EAX87514.1 - 0.0037 16.9 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87515.1 - 1.1e-72 243.5 4.2 1.4e-72 243.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX87515.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Ras PF00071.22 EAX87517.1 - 1.5e-11 44.2 0.0 1.8e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87517.1 - 6.1e-10 39.4 0.0 7.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Myb_DNA-binding PF00249.31 EAX87518.1 - 1.2e-20 73.4 1.8 2.3e-12 46.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87518.1 - 7.9e-16 58.1 3.7 1e-10 41.7 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX87518.1 - 1.3e-05 25.2 0.9 0.096 12.7 0.2 2.7 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX87518.1 - 0.0026 17.8 0.0 0.0074 16.3 0.0 1.8 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EAX87518.1 - 0.016 15.1 1.5 1 9.3 0.5 2.4 1 1 1 2 2 2 0 Myb DNA-binding like Nore1-SARAH PF16517.5 EAX87518.1 - 0.09 12.7 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF1574 PF07611.11 EAX87519.1 - 0.86 8.9 8.0 0.96 8.7 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) SecE PF00584.20 EAX87520.1 - 5e-08 32.8 0.3 5.8e-08 32.5 0.3 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF3447 PF11929.8 EAX87521.1 - 1.2e-38 130.9 7.1 1.2e-38 130.9 7.1 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX87521.1 - 8.8e-34 115.5 6.1 2.2e-09 37.7 0.0 7.0 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87521.1 - 2.2e-29 101.9 11.4 7.2e-16 58.6 2.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87521.1 - 3.4e-27 93.6 0.9 1.3e-07 31.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX87521.1 - 8.9e-26 87.1 5.3 8.8e-07 28.8 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX87521.1 - 1.7e-23 82.4 0.5 7.3e-10 38.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX87521.1 - 0.0055 16.8 3.2 6.3 7.0 0.2 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3718) PCI PF01399.27 EAX87522.1 - 4e-06 27.3 0.1 4e-06 27.3 0.1 2.8 3 2 2 5 5 5 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EAX87522.1 - 0.015 15.2 1.7 0.022 14.7 0.1 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Ribosomal_L22 PF00237.19 EAX87522.1 - 0.093 13.0 0.2 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Ank_2 PF12796.7 EAX87523.1 - 5.8e-71 235.1 50.9 5.5e-16 58.9 3.8 7.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87523.1 - 7.1e-66 216.0 16.3 8.3e-08 32.3 0.1 10.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 EAX87523.1 - 6.6e-62 205.1 18.7 5.8e-11 42.7 0.1 11.0 4 1 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87523.1 - 2.4e-53 171.9 19.2 2.1e-06 27.6 0.1 11.4 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EAX87523.1 - 1.9e-43 146.0 14.4 4.8e-11 42.7 0.4 6.7 6 1 1 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX87523.1 - 1.7e-39 133.6 7.6 1.7e-39 133.6 7.6 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX87523.1 - 2e-06 28.0 0.2 0.58 10.5 0.1 6.2 1 1 4 5 5 5 1 N terminal of Calcineurin-like phosphoesterase Prion PF00377.18 EAX87523.1 - 0.4 10.6 2.7 18 5.2 0.1 3.9 2 1 1 4 4 4 0 Prion/Doppel alpha-helical domain SH3_10 PF17902.1 EAX87524.1 - 0.0009 19.3 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 SH3 domain DUF2935 PF11155.8 EAX87524.1 - 0.37 11.1 5.9 0.5 10.7 2.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF4108 PF13390.6 EAX87525.1 - 9.2e-70 233.1 12.4 1.1e-69 232.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX87526.1 - 4.6e-131 435.6 11.5 4.6e-131 435.6 11.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX87526.1 - 1.6e-08 34.5 4.3 1.6e-08 34.5 4.3 4.9 5 1 0 5 5 5 2 Phage tail repeat like Amidase02_C PF12123.8 EAX87528.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87529.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) T5orf172 PF10544.9 EAX87531.1 - 4.5e-06 27.1 0.2 9.4e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87532.1 - 9.5e-34 115.6 0.5 2e-33 114.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX87532.1 - 0.22 12.2 1.6 18 6.1 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Pox_A32 PF04665.12 EAX87533.1 - 3.9e-07 29.8 2.3 3.9e-07 29.8 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX87533.1 - 3.5e-05 23.6 0.4 0.35 10.6 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX87533.1 - 4.6e-05 23.7 0.2 0.00034 20.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX87533.1 - 0.00026 21.0 4.1 0.0005 20.1 3.3 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87533.1 - 0.00073 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87533.1 - 0.0022 17.8 1.1 0.0042 16.9 0.8 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87533.1 - 0.0049 16.5 2.8 0.012 15.3 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87533.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87533.1 - 0.092 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87533.1 - 0.11 13.0 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87533.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein TPK_catalytic PF04263.16 EAX87533.1 - 0.14 12.2 0.6 1.8 8.7 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX87533.1 - 0.69 10.6 11.6 0.35 11.6 1.6 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX87533.1 - 0.74 10.1 4.8 9.9 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KIAA1430 PF13879.6 EAX87535.1 - 1.9e-15 57.4 3.6 1.9e-15 57.4 3.6 2.8 2 1 0 2 2 2 1 KIAA1430 homologue HABP4_PAI-RBP1 PF04774.15 EAX87535.1 - 5.1 8.0 22.0 0.26 12.1 15.7 2.0 2 1 1 3 3 3 0 Hyaluronan / mRNA binding family Pkinase PF00069.25 EAX87536.1 - 2.8e-27 95.7 1.2 3.8e-27 95.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87536.1 - 9.4e-13 48.0 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX87536.1 - 5.6e-11 41.8 0.2 5.6e-11 41.8 0.2 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAX87536.1 - 0.033 13.5 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RAMPs PF03787.15 EAX87536.1 - 0.086 12.9 1.3 0.16 12.0 1.3 1.4 1 0 0 1 1 1 0 RAMP superfamily APH PF01636.23 EAX87536.1 - 0.086 12.7 0.0 0.42 10.5 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family LRR_5 PF13306.6 EAX87538.1 - 1.2e-141 465.0 135.6 1.3e-27 96.2 14.0 8.1 2 2 7 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87538.1 - 2e-20 72.3 0.3 0.0018 18.0 0.0 10.7 9 3 4 13 13 13 4 Leucine rich repeat FNIP PF05725.12 EAX87538.1 - 2.6 8.3 9.7 22 5.3 0.2 5.4 4 1 0 4 4 4 0 FNIP Repeat SVWC PF15430.6 EAX87538.1 - 4.7 7.5 0.0 4.7 7.5 0.0 3.6 4 0 0 4 4 4 0 Single domain von Willebrand factor type C ARA70 PF12489.8 EAX87540.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Gly-zipper_Omp PF13488.6 EAX87541.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX87541.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX87541.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif LRR_5 PF13306.6 EAX87542.1 - 5.4e-27 94.3 9.7 1.6e-14 54.0 0.5 2.4 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87542.1 - 2.5e-07 30.4 0.1 0.0003 20.5 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 EAX87543.1 - 1.4e-77 257.8 58.6 4.6e-26 91.3 11.2 5.2 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87543.1 - 1.2e-12 47.4 0.3 0.001 18.8 0.0 6.5 5 2 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAX87543.1 - 0.00063 20.1 0.7 5.8 7.5 0.0 5.4 6 1 0 7 7 7 1 Leucine Rich repeats (2 copies) Toxin_R_bind_C PF07951.12 EAX87545.1 - 0.023 14.3 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Antimicrobial_8 PF08103.11 EAX87545.1 - 9.1 6.6 6.3 1.3 9.3 0.6 2.4 2 0 0 2 2 2 0 Uperin family PSP PF04046.16 EAX87546.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87547.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Gly_rich PF12810.7 EAX87548.1 - 1e-22 81.3 50.0 2.4e-22 80.0 50.0 1.5 1 0 0 1 1 1 1 Glycine rich protein VSP PF03302.13 EAX87548.1 - 1.4e-06 27.4 24.4 1.6e-05 24.0 24.4 2.2 1 1 0 1 1 1 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EAX87548.1 - 0.0042 17.2 23.2 0.33 11.1 12.3 2.6 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich TMEM154 PF15102.6 EAX87548.1 - 0.027 14.4 2.2 0.1 12.5 2.2 2.0 1 1 0 1 1 1 0 TMEM154 protein family GF_recep_IV PF14843.6 EAX87548.1 - 0.49 10.2 24.6 1.1 9.0 24.6 1.6 1 0 0 1 1 1 0 Growth factor receptor domain IV Tetraspanin PF00335.20 EAX87551.1 - 0.018 14.8 14.6 0.073 12.8 14.6 2.0 1 1 0 1 1 1 0 Tetraspanin family DuoxA PF10204.9 EAX87551.1 - 0.21 10.6 2.7 0.26 10.3 0.6 1.8 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF2207 PF09972.9 EAX87551.1 - 4.6 5.9 8.5 32 3.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ligase_CoA PF00549.19 EAX87552.1 - 9.8e-27 93.7 0.6 1.6e-26 93.0 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EAX87552.1 - 1.1e-26 93.3 1.0 1.1e-26 93.3 1.0 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EAX87552.1 - 7.6e-08 32.2 0.1 1.5e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain IlvN PF07991.12 EAX87552.1 - 0.00082 19.0 0.3 0.0016 18.0 0.3 1.6 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 EAX87552.1 - 0.002 19.0 2.1 0.0026 18.6 0.3 2.1 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 EAX87552.1 - 0.002 18.6 0.1 0.0041 17.6 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain ELFV_dehydrog PF00208.21 EAX87552.1 - 0.0063 16.3 0.2 0.013 15.2 0.1 1.5 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pup PF05639.11 EAX87553.1 - 0.45 11.5 11.8 0.064 14.2 5.7 2.6 2 0 0 2 2 2 0 Pup-like protein Herpes_LMP1 PF05297.11 EAX87553.1 - 4.6 6.3 6.6 5.2 6.2 6.0 1.3 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RP-C_C PF11800.8 EAX87553.1 - 5.9 6.9 7.7 53 3.8 7.7 2.2 1 1 0 1 1 1 0 Replication protein C C-terminal region Myb_DNA-binding PF00249.31 EAX87554.1 - 7.9e-28 96.4 6.5 9.1e-14 51.4 1.8 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87554.1 - 1.7e-25 89.0 8.7 3.2e-18 65.7 2.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX87554.1 - 1.4e-07 31.3 1.2 2.3e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX87554.1 - 3.3e-06 27.1 1.2 0.011 15.8 0.1 3.0 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX87554.1 - 0.00055 20.1 0.9 0.0014 18.8 0.1 1.9 1 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX87554.1 - 0.00071 19.6 1.7 0.21 11.7 0.3 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX87554.1 - 0.021 15.0 0.4 2.6 8.3 0.2 2.5 1 1 1 2 2 2 0 Rap1 Myb domain UPF0113_N PF17833.1 EAX87554.1 - 0.039 14.5 0.6 4.8 7.8 0.1 2.2 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain WIYLD PF10440.9 EAX87554.1 - 0.089 12.6 1.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain YqgF PF14639.6 EAX87555.1 - 0.075 12.8 0.5 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 DUF572 PF04502.13 EAX87555.1 - 0.27 10.8 13.4 0.44 10.1 13.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 EAX87555.1 - 0.65 8.5 12.9 0.97 7.9 12.9 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 EAX87555.1 - 4.1 6.1 8.3 6.6 5.4 8.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase TonB_N PF16031.5 EAX87555.1 - 5.7 7.5 12.3 11 6.5 12.3 1.4 1 0 0 1 1 1 0 TonB polyproline region Myb_DNA-binding PF00249.31 EAX87556.1 - 3.7e-23 81.4 0.4 8.3e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87556.1 - 1.4e-19 70.1 1.1 2.3e-09 37.3 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX87556.1 - 0.00031 20.6 0.2 0.082 12.8 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like QueF PF14489.6 EAX87556.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein SANT_DAMP1_like PF16282.5 EAX87556.1 - 0.036 14.3 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX87556.1 - 0.051 13.8 0.1 1.5 9.0 0.1 2.6 2 1 0 2 2 2 0 Rap1 Myb domain SLIDE PF09111.10 EAX87556.1 - 0.057 13.5 1.0 1.6 8.8 0.1 2.5 1 1 1 2 2 2 0 SLIDE Rap1_C PF11626.8 EAX87556.1 - 0.14 12.2 0.5 4.5 7.4 0.2 2.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF659 PF04937.15 EAX87557.1 - 0.021 14.7 0.0 0.085 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Pkinase PF00069.25 EAX87558.1 - 1.4e-48 165.6 0.1 6e-48 163.5 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87558.1 - 9.5e-22 77.5 0.0 5.9e-21 74.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87558.1 - 2.6e-05 23.7 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX87558.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EAX87558.1 - 0.14 11.1 0.2 0.79 8.6 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EAX87558.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ARA70 PF12489.8 EAX87559.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator PTR PF12789.7 EAX87561.1 - 2.5e-50 168.3 56.5 2.2e-29 101.3 16.7 6.5 4 2 2 6 6 6 4 Phage tail repeat like PH_TFIIH PF08567.11 EAX87561.1 - 0.41 11.0 3.6 22 5.5 0.1 3.2 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain CppA_C PF14507.6 EAX87561.1 - 1 10.2 4.3 1.9 9.2 1.3 2.9 2 1 0 2 2 2 0 CppA C-terminal DUF4795 PF16043.5 EAX87561.1 - 5.1 6.6 23.4 3.1 7.4 0.5 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) NUDIX PF00293.28 EAX87562.1 - 8.2e-15 55.0 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 EAX87562.1 - 6.5e-10 38.9 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain Glutaredoxin2_C PF04399.13 EAX87563.1 - 0.072 12.9 0.5 0.072 12.9 0.5 3.7 2 1 2 4 4 4 0 Glutaredoxin 2, C terminal domain Pep_M12B_propep PF01562.19 EAX87563.1 - 0.78 10.0 4.3 0.54 10.5 0.7 2.3 2 0 0 2 2 2 0 Reprolysin family propeptide GCR1_C PF12550.8 EAX87563.1 - 5.9 7.3 10.5 0.29 11.5 2.9 2.8 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes Peptidase_M18 PF02127.15 EAX87564.1 - 3.4e-52 177.7 0.0 4.6e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAX87564.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Nuc_deoxyri_tr3 PF11071.8 EAX87565.1 - 0.3 11.1 6.9 0.061 13.4 3.1 1.8 2 1 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ Fringe PF02434.16 EAX87569.1 - 0.012 15.1 0.7 0.95 8.8 0.7 2.1 1 1 1 2 2 2 0 Fringe-like HOCHOB PF17943.1 EAX87571.1 - 0.62 10.8 5.1 3 8.6 0.3 2.7 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox Thioredoxin_6 PF13848.6 EAX87572.1 - 5.1e-22 78.7 10.8 4.8e-15 55.9 0.5 4.0 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin PF00085.20 EAX87572.1 - 4.4e-10 39.5 0.0 1.9e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Kinetochor_Ybp2 PF08568.10 EAX87573.1 - 0.00033 19.3 34.6 2.8 6.3 0.6 7.0 1 1 6 7 7 7 7 Uncharacterised protein family, YAP/Alf4/glomulin CAAP1 PF15335.6 EAX87573.1 - 1.2 9.7 53.6 6.5 7.4 1.2 7.2 7 0 0 7 7 7 0 Caspase activity and apoptosis inhibitor 1 HK97-gp10_like PF04883.12 EAX87573.1 - 2.2 9.3 14.9 1.4e+02 3.5 1.0 6.3 1 1 4 5 5 5 0 Bacteriophage HK97-gp10, putative tail-component DUF3447 PF11929.8 EAX87574.1 - 1.2e-33 114.9 8.7 1.2e-33 114.9 8.7 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87574.1 - 1.5e-24 86.4 18.2 5.7e-15 55.7 3.7 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87574.1 - 2e-21 76.1 1.3 1e-10 41.9 0.1 5.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX87574.1 - 2.9e-18 65.4 4.8 2.7e-06 27.6 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX87574.1 - 1.5e-15 57.0 0.6 3.2e-08 33.7 0.1 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87574.1 - 3.7e-14 51.4 8.3 0.00025 21.3 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Cellulase-like PF12876.7 EAX87575.1 - 0.045 13.1 0.0 0.046 13.1 0.0 1.0 1 0 0 1 1 1 0 Sugar-binding cellulase-like PEPCK_N PF17297.2 EAX87575.1 - 0.14 11.8 0.1 0.16 11.5 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain HSP70 PF00012.20 EAX87576.1 - 1.5e-23 82.8 0.1 4.3e-23 81.4 0.1 1.6 1 1 0 1 1 1 1 Hsp70 protein DUF3410 PF11890.8 EAX87577.1 - 0.055 13.3 0.6 0.055 13.3 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3410) TPR_11 PF13414.6 EAX87577.1 - 0.22 11.2 3.1 11 5.8 0.4 2.8 2 0 0 2 2 2 0 TPR repeat Amidase PF01425.21 EAX87577.1 - 3.7 6.4 5.7 4.7 6.1 5.7 1.3 1 0 0 1 1 1 0 Amidase DUF883 PF05957.13 EAX87577.1 - 5.9 7.6 8.1 2.7 8.7 1.9 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PTR PF12789.7 EAX87579.1 - 5.4e-25 87.2 11.2 5.4e-25 87.2 11.2 4.6 5 1 1 6 6 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX87579.1 - 0.077 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Glyco_transf_64 PF09258.10 EAX87580.1 - 9.6e-37 126.6 0.2 1.2e-36 126.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF3781 PF12636.7 EAX87581.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF2939 PF11159.8 EAX87584.1 - 0.01 16.3 0.5 0.013 15.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX87584.1 - 1.5 8.9 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX87584.1 - 1.5 7.8 2.8 1.5 7.8 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF2400 PF09674.10 EAX87585.1 - 0.034 14.1 0.6 0.051 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX87585.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain T5orf172 PF10544.9 EAX87586.1 - 1.7e-06 28.5 0.5 5.7e-06 26.8 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX87586.1 - 0.15 11.5 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX87587.1 - 4.8e-156 517.4 12.8 6e-156 517.0 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87587.1 - 0.15 12.5 1.7 2.8 8.5 0.0 2.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 EAX87588.1 - 2.8e-52 177.6 0.0 4.2e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX87588.1 - 1.3e-48 165.7 0.0 2.3e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAX87588.1 - 0.00083 18.2 0.1 0.0013 17.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 EAX87588.1 - 0.054 13.5 0.0 2.9 8.1 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF4107 PF13389.6 EAX87589.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) TMEM154 PF15102.6 EAX87592.1 - 0.0011 18.9 0.1 0.0036 17.2 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family DUF4064 PF13273.6 EAX87592.1 - 0.017 15.4 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) RIFIN PF02009.16 EAX87592.1 - 0.03 14.2 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 EAX87592.1 - 0.037 14.9 1.4 0.11 13.4 1.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 EAX87592.1 - 0.056 13.4 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Orf78 PF06024.12 EAX87592.1 - 0.35 11.2 2.6 0.21 11.9 0.3 1.9 2 0 0 2 2 2 0 Orf78 (ac78) HSP70 PF00012.20 EAX87594.1 - 4.5e-104 348.8 3.7 1.7e-88 297.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAX87594.1 - 4.6e-11 42.1 0.0 4.2e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Spc7 PF08317.11 EAX87594.1 - 0.049 12.5 0.9 0.11 11.4 0.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein FAA_hydro_N_2 PF18288.1 EAX87594.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 FtsA PF14450.6 EAX87594.1 - 0.18 12.2 0.7 28 5.2 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA RapA_C PF12137.8 EAX87594.1 - 0.26 10.3 2.9 0.17 10.8 1.0 1.6 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Ank_2 PF12796.7 EAX87595.1 - 6.6e-31 106.7 9.9 1.4e-10 41.6 0.9 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87595.1 - 4.2e-25 87.8 3.1 9.7e-08 32.4 0.0 7.0 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX87595.1 - 5.1e-23 80.4 0.1 0.00093 19.5 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 EAX87595.1 - 1.9e-22 76.9 2.6 0.031 14.8 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 EAX87595.1 - 8.6e-17 60.9 5.5 8.6e-17 60.9 5.5 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX87595.1 - 1.5e-16 60.2 0.0 9.3e-07 29.0 0.0 6.3 3 2 5 8 8 8 4 Ankyrin repeats (many copies) BDV_G PF06208.11 EAX87595.1 - 0.0073 15.5 0.3 0.012 14.9 0.3 1.2 1 0 0 1 1 1 1 Borna disease virus G protein DUF3127 PF11325.8 EAX87595.1 - 0.17 12.2 0.3 3.4 8.0 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3127) partial_CstF PF15861.5 EAX87596.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Syndecan PF01034.20 EAX87597.1 - 4.7e-05 23.2 0.4 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 Syndecan domain DUF4690 PF15756.5 EAX87597.1 - 0.0021 18.6 1.5 0.01 16.4 0.4 2.8 1 1 1 2 2 2 1 Small Novel Rich in Cartilage SecG PF03840.14 EAX87597.1 - 0.0041 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Preprotein translocase SecG subunit Sec-ASP3 PF15432.6 EAX87597.1 - 0.0055 16.9 1.1 0.21 11.7 0.1 3.5 3 0 0 3 3 3 1 Accessory Sec secretory system ASP3 TMEM154 PF15102.6 EAX87597.1 - 0.019 14.9 0.2 0.047 13.6 0.2 1.7 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 EAX87597.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EAX87597.1 - 0.031 15.1 0.0 0.071 14.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Big_3_3 PF13750.6 EAX87597.1 - 0.053 13.2 2.8 0.18 11.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) PilM_2 PF11104.8 EAX87597.1 - 0.066 12.2 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; ODV-E18 PF10717.9 EAX87597.1 - 0.28 11.1 5.4 0.081 12.8 1.3 2.0 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Insulin_TMD PF17870.1 EAX87597.1 - 0.52 10.4 3.6 1.2 9.3 3.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment partial_CstF PF15861.5 EAX87598.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF2362 PF10154.9 EAX87599.1 - 0.0072 15.3 7.6 0.0089 15.0 6.7 1.4 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2362) KilA-N PF04383.13 EAX87600.1 - 7.6e-33 112.7 0.1 7.6e-33 112.7 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX87600.1 - 0.0043 17.2 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX87602.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87602.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87602.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87602.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87602.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87602.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87602.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87602.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87602.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87602.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87602.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX87602.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX87604.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) HALZ PF02183.18 EAX87605.1 - 0.00048 20.3 1.4 0.00048 20.3 1.4 7.3 6 2 1 7 7 6 1 Homeobox associated leucine zipper APG6_N PF17675.1 EAX87605.1 - 0.0033 17.9 8.7 0.0033 17.9 8.7 4.9 1 1 4 5 5 5 1 Apg6 coiled-coil region GAS PF13851.6 EAX87605.1 - 0.0071 15.7 82.0 0.094 12.1 10.6 4.2 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAX87605.1 - 0.008 16.6 2.2 0.008 16.6 2.2 7.1 2 1 3 5 5 4 3 Cell division protein ZapB Seryl_tRNA_N PF02403.22 EAX87605.1 - 0.01 16.0 12.4 0.01 16.0 12.4 5.4 1 1 4 5 5 4 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 EAX87605.1 - 0.016 15.4 7.6 0.016 15.4 7.6 5.9 2 2 2 5 5 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EAX87605.1 - 0.032 14.0 2.2 0.032 14.0 2.2 7.6 1 1 6 8 8 7 0 Septum formation initiator CENP-F_leu_zip PF10473.9 EAX87605.1 - 0.035 14.1 1.4 0.027 14.5 10.9 4.1 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EAX87605.1 - 0.043 12.7 77.9 0.067 12.1 11.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 EAX87605.1 - 0.092 12.3 66.8 0.42 10.2 10.7 4.0 1 1 3 4 4 4 0 Intermediate filament protein ATG16 PF08614.11 EAX87605.1 - 0.39 10.9 76.9 0.086 13.1 27.0 4.7 1 1 1 3 3 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EAX87605.1 - 0.64 8.6 63.0 0.91 8.1 31.2 2.7 1 1 1 2 2 2 0 AAA domain TACC_C PF05010.14 EAX87605.1 - 0.67 9.7 70.9 0.096 12.5 15.4 3.4 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Golgin_A5 PF09787.9 EAX87605.1 - 0.79 9.1 73.2 2.3 7.6 10.3 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF3584 PF12128.8 EAX87605.1 - 1.1 6.6 65.8 0.055 11.0 16.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EAX87605.1 - 1.7 8.7 50.1 0.067 13.2 2.5 4.8 1 1 5 6 6 5 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EAX87605.1 - 4.4 5.7 4.4 1.7 7.1 0.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 EAX87605.1 - 5 7.5 67.0 0.36 11.3 13.5 3.5 1 1 2 3 3 2 0 Fez1 TPR_MLP1_2 PF07926.12 EAX87605.1 - 5.3 7.1 76.4 0.38 10.8 8.9 4.6 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EAX87605.1 - 9.5 4.3 71.3 1.5 6.9 31.2 3.8 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA LRR_4 PF12799.7 EAX87606.1 - 1.3e-07 31.8 3.6 0.0036 17.7 0.1 2.9 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX87606.1 - 6.5e-06 25.7 0.1 1.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAX87606.1 - 0.00019 21.2 0.5 0.00058 19.6 0.4 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EAX87606.1 - 0.01 15.9 0.4 24 5.3 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EAX87606.1 - 0.25 12.0 1.0 40 5.3 0.0 3.3 2 1 0 2 2 2 0 Leucine Rich Repeat Ank_4 PF13637.6 EAX87607.1 - 7e-06 26.5 0.0 8.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX87607.1 - 1.8e-05 24.9 0.0 0.28 11.7 0.0 2.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX87607.1 - 0.00047 20.4 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87607.1 - 0.045 14.3 0.1 8.5 7.3 0.1 2.5 2 1 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EAX87607.1 - 0.077 13.6 0.0 0.084 13.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 EAX87608.1 - 5.4e-05 23.5 0.1 0.00039 20.7 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EAX87608.1 - 8.5e-05 23.1 0.1 0.00023 21.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87608.1 - 0.0029 18.0 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX87608.1 - 0.0034 17.9 0.1 0.011 16.3 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87608.1 - 0.094 13.1 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Orthoreo_P10 PF07204.11 EAX87609.1 - 0.007 16.3 0.3 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Orthoreovirus membrane fusion protein p10 DUF1515 PF07439.11 EAX87611.1 - 0.34 11.0 5.0 0.78 9.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1465 PF07323.12 EAX87611.1 - 1.8 8.4 6.5 2.3 8.0 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF1664 PF07889.12 EAX87611.1 - 9.8 6.2 11.9 2.3 8.3 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2533 PF10752.9 EAX87613.1 - 0.26 11.7 2.1 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Helicase_C PF00271.31 EAX87614.1 - 3e-05 24.3 0.2 0.0022 18.3 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DDE_1 PF03184.19 EAX87615.1 - 3.3e-13 49.7 0.1 7.8e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease FYVE_2 PF02318.16 EAX87616.1 - 0.05 13.8 0.2 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DDE_Tnp_4 PF13359.6 EAX87617.1 - 9.1e-30 103.4 0.1 1.3e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX87617.1 - 8.6e-15 55.0 0.1 1.6e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX87617.1 - 0.0041 16.8 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Plant_tran PF04827.14 EAX87617.1 - 0.012 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Plant transposon protein c-SKI_SMAD_bind PF08782.10 EAX87617.1 - 0.027 14.7 0.9 10 6.4 0.2 3.2 3 0 0 3 3 3 0 c-SKI Smad4 binding domain PspB PF06667.12 EAX87617.1 - 0.057 13.5 0.0 0.29 11.2 0.0 2.2 3 0 0 3 3 3 0 Phage shock protein B DUF2486 PF10667.9 EAX87617.1 - 0.26 11.5 5.2 0.36 11.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) SPATA3 PF15662.5 EAX87617.1 - 0.27 11.9 6.2 0.65 10.6 6.2 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF4108 PF13390.6 EAX87619.1 - 5.9e-63 211.1 6.8 6.6e-63 210.9 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX87620.1 - 0.021 14.9 1.0 0.3 11.2 0.7 2.3 1 1 1 2 2 2 0 Phage tail repeat like DUF1471 PF07338.13 EAX87620.1 - 0.16 11.9 1.1 2.7 8.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1471) DUF19 PF01579.18 EAX87622.1 - 0.0076 16.1 0.6 0.011 15.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF19) Mei5_like PF17021.5 EAX87622.1 - 0.033 14.2 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative double-strand recombination repair-like IBD PF10416.9 EAX87623.1 - 1.3e-17 64.0 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD SEP PF08059.13 EAX87624.1 - 2.2e-09 37.8 0.1 5.8e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 SEP domain Spc29 PF17082.5 EAX87624.1 - 0.00023 21.1 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 YabA PF06156.13 EAX87624.1 - 0.0017 18.9 1.9 0.006 17.2 1.7 2.0 2 1 0 2 2 2 1 Initiation control protein YabA ZapB PF06005.12 EAX87624.1 - 0.026 15.0 6.9 0.086 13.3 6.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 EAX87624.1 - 0.12 13.0 2.5 0.13 12.8 1.0 1.8 2 0 0 2 2 2 0 SlyX DUF16 PF01519.16 EAX87624.1 - 0.56 10.7 6.5 0.35 11.4 2.0 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 DivIC PF04977.15 EAX87624.1 - 2.9 7.7 9.2 0.15 11.9 2.5 2.2 3 0 0 3 3 3 0 Septum formation initiator DHHC PF01529.20 EAX87625.1 - 2e-25 89.5 10.9 2e-25 89.5 10.9 3.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase CRA PF06589.11 EAX87625.1 - 0.11 12.6 0.4 0.3 11.2 0.4 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ribosomal_L32e PF01655.18 EAX87626.1 - 3.1e-36 124.1 0.0 3.7e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Mitoc_mL59 PF18126.1 EAX87626.1 - 0.021 15.1 0.3 0.057 13.7 0.3 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Ribosomal_S17_N PF16205.5 EAX87627.1 - 5.6e-28 97.1 0.5 9.6e-28 96.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAX87627.1 - 8.9e-27 93.0 0.8 1.7e-26 92.1 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 PCB_OB PF17092.5 EAX87627.1 - 0.017 15.8 0.0 0.031 15.0 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF5487 PF17589.2 EAX87627.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5487) OmdA PF13376.6 EAX87627.1 - 2.4 8.2 5.5 2.5 8.2 1.3 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ank_2 PF12796.7 EAX87628.1 - 6.7e-06 26.6 0.3 0.018 15.6 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX87628.1 - 0.0022 17.9 1.3 0.0022 17.9 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX87628.1 - 0.018 15.5 0.1 30 5.6 0.0 3.8 2 1 2 4 4 4 0 Ankyrin repeat DUF1823 PF08853.11 EAX87628.1 - 0.036 14.2 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) Anemone_cytotox PF06369.12 EAX87628.1 - 0.075 12.7 0.3 2.7 7.6 0.3 2.2 2 0 0 2 2 2 0 Sea anemone cytotoxic protein Ank PF00023.30 EAX87628.1 - 0.17 12.4 1.7 28 5.4 0.0 3.1 4 0 0 4 4 4 0 Ankyrin repeat Not1 PF04054.15 EAX87629.1 - 5.1e-19 68.4 0.6 6.3e-16 58.3 2.1 2.9 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAX87629.1 - 2.7e-14 53.1 0.1 8.4e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT PF16418.5 EAX87629.1 - 3.3e-07 30.5 0.7 1.5e-06 28.3 0.3 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3819 PF12842.7 EAX87629.1 - 1.9e-06 27.9 0.7 4.9e-06 26.6 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EAX87629.1 - 0.0069 15.6 0.0 0.11 11.7 0.0 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF2718 PF10918.8 EAX87630.1 - 1.1 9.8 8.8 0.72 10.4 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2718) DDE_Tnp_4 PF13359.6 EAX87631.1 - 2.5e-29 102.0 0.0 6.1e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX87631.1 - 3e-09 36.7 0.0 6.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAX87631.1 - 3.9e-05 23.4 0.1 0.00016 21.4 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain UCH_1 PF13423.6 EAX87631.1 - 0.00077 19.1 0.1 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Fungal_lectin_2 PF18647.1 EAX87631.1 - 0.097 13.1 0.1 0.31 11.5 0.1 1.9 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin DUF4107 PF13389.6 EAX87632.1 - 1.9e-71 239.4 3.6 2.9e-71 238.8 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX87633.1 - 0.0022 17.6 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX87635.1 - 4.2e-16 58.7 30.1 3.4e-08 33.4 4.8 5.3 5 0 0 5 5 5 4 Phage tail repeat like Collagen PF01391.18 EAX87635.1 - 4.9e-09 35.8 20.6 8.1e-09 35.1 20.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX87635.1 - 0.0073 16.4 4.9 0.023 14.8 0.0 3.2 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 EAX87635.1 - 0.43 10.9 3.5 1.1 9.6 0.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) RecG_N PF17190.4 EAX87635.1 - 1 10.2 8.3 44 4.9 0.0 4.8 6 0 0 6 6 6 0 RecG N-terminal helical domain TA_inhibitor PF17574.2 EAX87635.1 - 1.5 8.9 7.3 35 4.5 0.1 4.1 5 0 0 5 5 5 0 Inhibitor of toxin/antitoxin system (Gp4.5) NPV_P10 PF05531.12 EAX87635.1 - 4.8 7.7 9.7 45 4.6 0.2 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Gly_rich PF12810.7 EAX87637.1 - 4.6e-34 118.4 36.9 5.3e-34 118.2 36.9 1.0 1 0 0 1 1 1 1 Glycine rich protein IceA2 PF05862.11 EAX87637.1 - 0.31 11.0 1.8 14 5.7 0.3 2.4 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Ax_dynein_light PF10211.9 EAX87638.1 - 1e-05 25.6 0.4 1e-05 25.6 0.4 3.1 1 1 1 2 2 2 1 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 EAX87638.1 - 0.00084 19.4 5.1 0.00084 19.4 5.1 3.0 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_3 PF13758.6 EAX87638.1 - 0.17 12.0 5.4 0.15 12.1 2.6 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF948 PF06103.11 EAX87638.1 - 0.2 11.9 8.0 5.8 7.2 4.1 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliT PF05400.13 EAX87638.1 - 0.27 12.1 7.8 20 6.1 0.0 4.1 3 1 1 4 4 4 0 Flagellar protein FliT GldM_N PF12081.8 EAX87638.1 - 0.31 11.1 13.8 0.059 13.5 2.9 3.0 2 1 1 3 3 3 0 GldM N-terminal domain DUF1664 PF07889.12 EAX87638.1 - 0.52 10.3 12.1 0.31 11.1 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 EAX87638.1 - 2.1 8.7 10.8 2 8.8 0.6 4.5 3 1 1 4 4 4 0 Tup N-terminal DUF1043 PF06295.12 EAX87638.1 - 3.9 7.5 10.4 1.1 9.2 0.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) KASH_CCD PF14662.6 EAX87638.1 - 4.1 7.2 27.1 0.033 14.0 17.7 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HofP PF10748.9 EAX87640.1 - 0.062 12.9 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 DNA utilization proteins HofP REPA_OB_2 PF16900.5 EAX87641.1 - 2.4e-25 88.3 5.4 9.8e-19 67.1 0.5 3.5 3 0 0 3 3 3 3 Replication protein A OB domain Rep_fac-A_C PF08646.10 EAX87641.1 - 5.2e-25 87.9 1.1 2.4e-23 82.5 0.1 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 EAX87641.1 - 2.5e-10 40.2 3.5 5.4e-08 32.7 0.0 3.8 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EAX87641.1 - 0.00056 19.9 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.14 EAX87641.1 - 0.00078 19.7 0.6 0.0027 18.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF4539 PF15072.6 EAX87641.1 - 0.031 14.3 0.2 3.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Ribosom_S12_S23 PF00164.25 EAX87641.1 - 0.13 11.8 0.9 0.41 10.3 0.1 2.2 3 0 0 3 3 3 0 Ribosomal protein S12/S23 RecJ_OB PF17768.1 EAX87641.1 - 0.3 11.4 2.6 10 6.4 0.0 3.5 4 0 0 4 4 4 0 RecJ OB domain Ank_4 PF13637.6 EAX87642.1 - 7.5e-42 141.2 13.8 1e-11 45.1 0.1 7.5 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87642.1 - 1.1e-38 131.7 23.8 2.2e-15 57.0 0.7 4.8 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX87642.1 - 5.4e-37 125.6 3.4 5.4e-37 125.6 3.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX87642.1 - 4.9e-32 109.0 8.5 1.5e-09 37.9 0.1 6.0 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX87642.1 - 1e-30 102.3 4.2 1.4e-06 28.2 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX87642.1 - 3.9e-19 68.5 7.7 1.2e-07 31.8 0.1 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) PH_8 PF15409.6 EAX87642.1 - 0.0045 17.2 0.2 55 4.1 0.0 4.2 2 1 1 4 4 4 0 Pleckstrin homology domain DUF3718 PF12514.8 EAX87642.1 - 0.013 15.6 0.7 33 4.7 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3718) DRTGG PF07085.12 EAX87642.1 - 0.044 13.6 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 0 DRTGG domain CREPT PF16566.5 EAX87643.1 - 0.031 14.4 0.3 0.072 13.3 0.3 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX87643.1 - 0.93 9.7 5.6 0.33 11.1 1.6 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5359 PF17313.2 EAX87644.1 - 0.065 13.2 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5359) PSP PF04046.16 EAX87645.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MliC PF09864.9 EAX87646.1 - 0.079 12.9 0.1 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF4107 PF13389.6 EAX87648.1 - 2.2e-72 242.5 3.1 3e-72 242.1 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX87651.1 - 1.3e-155 515.9 12.3 1.7e-155 515.6 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX87651.1 - 0.056 13.3 0.7 0.26 11.2 0.1 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX87651.1 - 0.094 13.2 3.0 0.7 10.4 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX87651.1 - 0.1 12.9 2.3 13 6.2 0.0 3.6 4 1 0 4 4 4 0 Tup N-terminal Rx_N PF18052.1 EAX87651.1 - 0.35 11.2 2.9 5.4 7.4 0.0 3.2 2 2 0 2 2 2 0 Rx N-terminal domain KilA-N PF04383.13 EAX87652.1 - 1.5e-44 150.4 1.0 3.4e-44 149.3 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX87652.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) LOH1CR12 PF10158.9 EAX87652.1 - 0.98 9.4 5.0 1 9.4 0.4 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DNA_pol_B_2 PF03175.13 EAX87653.1 - 7.1e-10 38.3 3.0 3.2e-09 36.2 3.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX87653.1 - 0.11 11.1 2.4 3.8 6.1 1.7 3.0 2 1 0 2 2 2 0 DNA polymerase family B gpUL132 PF11359.8 EAX87653.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX87653.1 - 0.15 12.0 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor KilA-N PF04383.13 EAX87654.1 - 8e-35 119.1 0.6 1.6e-34 118.1 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX87654.1 - 0.61 10.1 3.9 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX87655.1 - 1e-06 29.2 0.1 2.5e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87655.1 - 0.0063 16.4 1.1 0.045 13.6 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX87656.1 - 1.9e-144 479.4 11.0 2.4e-144 479.1 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf_CopZ PF18423.1 EAX87656.1 - 0.18 11.8 0.3 0.18 11.8 0.3 1.9 2 0 0 2 2 2 0 Zinc binding domain zf-C4pol PF14260.6 EAX87656.1 - 1.2 9.7 4.2 5.8 7.5 0.1 2.7 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX87656.1 - 9.7 6.7 8.4 3.3 8.2 1.0 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX87658.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87659.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Gly_rich PF12810.7 EAX87660.1 - 3e-09 37.2 1.5 3.9e-09 36.8 1.5 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX87661.1 - 2.4e-118 389.6 88.9 4.3e-24 84.9 13.7 7.8 2 2 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87661.1 - 3.1e-22 78.1 11.2 0.00058 19.6 0.0 8.7 6 2 2 8 8 8 6 Leucine rich repeat DUF4106 PF13388.6 EAX87662.1 - 7.5e-252 835.8 22.9 7.5e-252 835.8 22.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Phosphonate-bd PF12974.7 EAX87662.1 - 0.0039 16.8 1.1 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein KAR PF15222.6 EAX87662.1 - 0.086 13.1 2.4 1.3 9.3 0.2 3.2 3 0 0 3 3 3 0 Kidney androgen-regulated T5orf172 PF10544.9 EAX87663.1 - 5.3e-07 30.1 0.4 1.1e-06 29.2 0.4 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87664.1 - 2.7e-40 136.7 0.3 7e-40 135.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX87664.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX87665.1 - 7.4e-07 28.9 2.8 7.4e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87665.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87665.1 - 5.3e-05 23.0 0.3 0.33 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87665.1 - 0.00021 21.3 3.9 0.00052 20.0 4.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87665.1 - 0.00052 19.8 0.1 0.00093 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87665.1 - 0.0015 18.4 0.8 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87665.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87665.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87665.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX87665.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX87665.1 - 0.089 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX87665.1 - 0.24 11.7 5.1 3.3 8.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX87667.1 - 3.3e-61 205.4 8.1 3.6e-61 205.3 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX87668.1 - 1.3e-35 121.8 2.1 1.6e-18 67.1 0.1 3.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87668.1 - 2.6e-18 66.1 0.2 9.6e-08 32.4 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX87668.1 - 7.7e-13 48.3 1.2 1.3e-06 28.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX87668.1 - 1.2e-12 47.8 0.0 8.8e-06 25.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87668.1 - 1.7e-12 46.3 0.0 0.0034 17.8 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX87669.1 - 1.2e-21 77.1 0.0 3e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87669.1 - 7.5e-21 74.2 0.0 1.8e-10 41.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX87669.1 - 7.4e-19 67.3 0.0 2.8e-06 27.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX87669.1 - 9.6e-16 56.3 0.0 0.00012 22.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX87669.1 - 6e-15 55.1 0.0 1.1e-08 35.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Raptor_N PF14538.6 EAX87670.1 - 3.3e-35 121.2 0.0 9.1e-35 119.8 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 EAX87670.1 - 7e-07 29.5 0.0 1.8e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 EAX87670.1 - 0.0031 17.6 0.7 0.0068 16.5 0.7 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX87670.1 - 0.033 14.4 0.0 2.8 8.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat SYCP2_ARLD PF18581.1 EAX87671.1 - 0.084 12.9 0.2 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain Ricin_B_lectin PF00652.22 EAX87672.1 - 0.011 16.0 0.0 0.83 9.9 0.0 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAX87672.1 - 0.047 14.4 0.0 2 9.2 0.0 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF4108 PF13390.6 EAX87673.1 - 8.7e-58 194.3 5.0 9.7e-58 194.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX87674.1 - 0.66 9.9 3.7 1.4 8.9 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX87675.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87675.1 - 2.9e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87675.1 - 5.2e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87675.1 - 0.00012 22.2 2.8 0.00028 20.9 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87675.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87675.1 - 0.0014 18.5 0.6 0.0031 17.3 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87675.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87675.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX87675.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX87675.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87675.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87675.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX87675.1 - 0.16 12.4 3.2 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX87675.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX87676.1 - 1e-42 144.5 0.8 1.8e-42 143.7 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX87676.1 - 0.03 14.9 0.2 0.1 13.2 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX87677.1 - 3e-154 511.5 15.8 3.8e-154 511.1 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87677.1 - 0.091 13.2 3.3 1.8 9.1 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX87677.1 - 0.12 12.2 0.7 0.33 10.8 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX87677.1 - 0.13 12.7 0.4 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX87677.1 - 0.18 12.3 0.2 0.18 12.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3839 PF12943.7 EAX87678.1 - 1.5e-155 515.7 14.6 1.9e-155 515.4 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX87678.1 - 0.089 13.4 4.8 0.93 10.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX87678.1 - 0.29 11.4 1.4 0.97 9.8 0.5 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX87678.1 - 0.49 10.9 7.5 2.5 8.6 1.6 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3447 PF11929.8 EAX87679.1 - 2.8e-11 43.2 0.5 5.4e-11 42.3 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) ubiquitin PF00240.23 EAX87680.1 - 1.5e-13 50.3 2.3 3.2e-13 49.2 2.3 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EAX87680.1 - 6e-05 22.8 2.2 0.00011 21.9 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EAX87680.1 - 0.0073 16.3 1.0 0.014 15.4 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX87680.1 - 0.018 15.4 1.3 0.036 14.4 1.3 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX87680.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L23 PF00276.20 EAX87680.1 - 0.048 14.0 0.2 0.13 12.7 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L23 DUF2407 PF10302.9 EAX87680.1 - 0.056 14.0 0.9 0.1 13.2 0.9 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Pkinase PF00069.25 EAX87681.1 - 1.9e-30 106.1 0.1 2.8e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX87681.1 - 4.5e-20 72.0 0.0 6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX87681.1 - 2.8e-05 23.6 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like JmjC PF02373.22 EAX87681.1 - 0.076 13.4 1.1 0.38 11.2 0.4 2.3 1 1 1 2 2 2 0 JmjC domain, hydroxylase DUF4720 PF15846.5 EAX87682.1 - 0.019 14.8 0.1 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4720) Tctex-1 PF03645.13 EAX87683.1 - 1.8e-11 44.2 0.5 2.2e-11 43.9 0.5 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF2015 PF09435.10 EAX87683.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Profilin PF00235.19 EAX87684.1 - 1e-20 74.3 0.6 1.1e-20 74.1 0.6 1.0 1 0 0 1 1 1 1 Profilin DUF1126 PF06565.12 EAX87685.1 - 1.3e-93 307.8 1.3 1.4e-33 114.8 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 EAX87685.1 - 0.0045 17.3 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator, RHH-like, CopG DUF4107 PF13389.6 EAX87686.1 - 1.1e-66 224.0 2.8 1.5e-66 223.6 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAX87688.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX87689.1 - 1.7e-08 34.3 1.1 4e-08 33.0 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX87689.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX87689.1 - 0.064 13.1 2.3 0.11 12.4 2.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 AbiJ_NTD4 PF18863.1 EAX87690.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX87690.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein EamA PF00892.20 EAX87691.1 - 3.4e-16 59.6 31.0 7.6e-10 39.1 9.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3671 PF12420.8 EAX87691.1 - 0.22 11.6 3.9 2.3 8.3 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function YtpI PF14007.6 EAX87691.1 - 0.46 10.7 0.1 0.46 10.7 0.1 4.0 4 1 0 4 4 4 0 YtpI-like protein PARP_reg PF02877.14 EAX87692.1 - 0.038 14.1 0.5 0.055 13.6 0.5 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain HSP70 PF00012.20 EAX87693.1 - 1.6e-92 310.7 2.9 3.6e-92 309.5 2.9 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX87693.1 - 1.7e-13 50.1 0.2 6.6e-12 44.9 0.3 2.5 2 1 0 2 2 2 1 MreB/Mbl protein CheZ PF04344.13 EAX87693.1 - 0.0065 16.4 1.7 0.0065 16.4 1.7 1.8 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ FTA4 PF13093.6 EAX87693.1 - 0.01 15.8 1.8 0.019 14.8 1.8 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ABC_tran_CTD PF16326.5 EAX87693.1 - 0.02 15.1 5.1 0.02 15.1 5.1 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain WHEP-TRS PF00458.20 EAX87693.1 - 0.65 10.2 0.0 0.65 10.2 0.0 2.5 3 0 0 3 3 3 0 WHEP-TRS domain AAA_23 PF13476.6 EAX87693.1 - 0.8 10.2 13.6 2.4 8.6 9.3 2.5 2 0 0 2 2 2 0 AAA domain PCRF PF03462.18 EAX87693.1 - 0.97 9.3 7.4 1.1 9.1 4.4 2.2 2 0 0 2 2 2 0 PCRF domain DUF948 PF06103.11 EAX87693.1 - 5.1 7.4 5.2 9.1 6.6 2.2 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 EAX87694.1 - 8.9e-61 202.5 28.4 8.7e-19 67.9 3.7 5.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87694.1 - 3.3e-58 193.4 19.6 7.4e-13 48.7 0.2 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87694.1 - 8.8e-44 142.5 15.4 9e-06 25.7 0.2 8.2 8 1 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 EAX87694.1 - 6e-43 143.5 13.1 2.7e-07 30.7 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX87694.1 - 1.7e-39 133.3 17.0 4.5e-11 42.8 0.0 5.7 2 1 3 6 6 6 5 Ankyrin repeats (many copies) CCDC84 PF14968.6 EAX87694.1 - 0.015 15.0 0.5 0.99 9.0 0.1 2.8 2 1 0 2 2 2 0 Coiled coil protein 84 Lipoprotein_3 PF00938.17 EAX87694.1 - 0.046 13.9 1.1 0.7 10.1 0.2 2.5 1 1 1 2 2 2 0 Lipoprotein NTP_transf_6 PF06042.11 EAX87694.1 - 0.063 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase Stap_Strp_toxin PF01123.20 EAX87694.1 - 0.19 12.6 10.2 0.14 13.0 0.7 4.4 2 2 2 5 5 5 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3447 PF11929.8 EAX87695.1 - 8.5e-18 64.1 5.8 8.5e-18 64.1 5.8 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX87695.1 - 0.014 15.9 0.6 0.092 13.3 0.2 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ret2_MD PF18528.1 EAX87695.1 - 0.21 12.0 0.8 4.5 7.7 0.1 2.7 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Ank_3 PF13606.6 EAX87695.1 - 0.61 10.8 2.4 20 6.2 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeat Glyco_hydro_47 PF01532.20 EAX87696.1 - 8.9e-114 380.9 0.1 1e-113 380.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4126 PF13548.6 EAX87696.1 - 0.23 11.1 0.2 0.6 9.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) PSP PF04046.16 EAX87697.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87698.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87699.1 - 0.029 14.9 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX87699.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAX87700.1 - 4.8e-36 122.6 24.9 1.4e-32 111.5 13.7 6.5 4 2 2 6 6 6 3 Phage tail repeat like DUF4106 PF13388.6 EAX87701.1 - 1.2e-271 901.0 22.0 1.2e-271 901.0 22.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Cu-oxidase_2 PF07731.14 EAX87702.1 - 0.042 13.6 0.2 0.087 12.6 0.2 1.6 1 0 0 1 1 1 0 Multicopper oxidase DUF5126 PF17166.4 EAX87702.1 - 0.049 13.5 0.2 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) NUMOD4 PF07463.11 EAX87702.1 - 0.055 13.7 0.7 0.23 11.7 0.7 2.2 1 1 0 1 1 1 0 NUMOD4 motif PSP PF04046.16 EAX87704.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87705.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX87707.1 - 6e-27 93.5 12.8 6e-27 93.5 12.8 4.0 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX87707.1 - 0.044 13.5 0.9 0.091 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PKcGMP_CC PF16808.5 EAX87707.1 - 0.16 11.9 1.4 3.1 7.7 0.3 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Mei5_like PF17021.5 EAX87710.1 - 0.14 12.2 3.9 0.33 11.0 3.9 1.7 1 0 0 1 1 1 0 Putative double-strand recombination repair-like EF-hand_7 PF13499.6 EAX87711.1 - 3.1e-19 69.2 7.4 4.6e-10 39.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX87711.1 - 2.7e-18 64.1 10.7 2.6e-07 29.7 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EAX87711.1 - 5.3e-18 64.6 9.5 9.9e-11 41.3 1.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAX87711.1 - 4.3e-15 54.3 4.7 4.3e-07 29.4 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EAX87711.1 - 1.6e-10 39.9 5.5 9e-05 21.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EAX87711.1 - 2.3e-07 31.0 0.2 9.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain DUF3008 PF11450.8 EAX87711.1 - 1.5e-06 28.2 2.9 0.02 15.0 0.2 2.4 2 0 0 2 2 2 2 Protein of unknwon function (DUF3008) Caleosin PF05042.13 EAX87711.1 - 1.1e-05 25.5 1.0 2.7 7.9 0.0 3.2 2 1 1 3 3 3 3 Caleosin related protein UPF0154 PF03672.13 EAX87711.1 - 0.00015 21.8 0.1 0.0038 17.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF1456 PF07308.13 EAX87711.1 - 0.0009 19.5 1.8 0.08 13.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) SurA_N_2 PF13623.6 EAX87711.1 - 0.0013 18.7 0.3 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 EAX87711.1 - 0.0025 18.1 1.3 1.9 8.8 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PhetRS_B1 PF18262.1 EAX87711.1 - 0.01 16.0 0.6 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EspA PF03433.13 EAX87711.1 - 0.043 13.6 0.1 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 EspA-like secreted protein EF-hand_14 PF17959.1 EAX87711.1 - 0.052 13.9 1.9 3.2 8.2 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain Armet PF10208.9 EAX87711.1 - 0.067 13.1 1.4 11 5.9 0.4 2.7 1 1 2 3 3 3 0 Degradation arginine-rich protein for mis-folding DUF2789 PF10982.8 EAX87711.1 - 0.11 12.6 0.4 4.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) Mst1_SARAH PF11629.8 EAX87711.1 - 0.12 12.5 3.2 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 EF-hand_4 PF12763.7 EAX87711.1 - 0.3 11.1 2.1 7.9 6.5 0.3 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Bromodomain PF00439.25 EAX87712.1 - 7.6e-05 22.7 0.8 0.00023 21.1 0.8 1.9 1 0 0 1 1 1 1 Bromodomain DUF4411 PF14367.6 EAX87712.1 - 0.09 12.7 4.2 0.1 12.5 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) DUF4107 PF13389.6 EAX87714.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX87714.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX87715.1 - 0.0083 15.8 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX87716.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3839 PF12943.7 EAX87718.1 - 6e-110 366.4 8.9 6.9e-110 366.2 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2547 PF10818.8 EAX87718.1 - 0.16 12.9 0.7 4.2 8.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) DUF3839 PF12943.7 EAX87719.1 - 7.9e-26 91.0 4.9 1.1e-25 90.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRE_C2HC PF07530.11 EAX87719.1 - 0.06 13.5 0.3 0.31 11.2 0.3 2.1 1 1 0 1 1 1 0 Associated with zinc fingers Aminotran_1_2 PF00155.21 EAX87719.1 - 0.13 11.4 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2897 PF11446.8 EAX87720.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX87721.1 - 3.5e-64 215.0 6.2 3.9e-64 214.9 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX87721.1 - 0.12 12.6 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide F5_F8_type_C PF00754.25 EAX87722.1 - 3.3e-05 24.0 0.1 6.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 EAX87722.1 - 0.023 14.8 0.2 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch Pox_H7 PF04787.12 EAX87722.1 - 0.089 13.3 0.2 4.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Late protein H7 Ank_2 PF12796.7 EAX87723.1 - 5.1e-17 62.2 2.2 7.6e-06 26.4 0.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX87723.1 - 6.5e-13 48.9 0.2 3.3e-05 24.4 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX87723.1 - 6.1e-10 39.1 5.6 2.4e-06 27.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX87723.1 - 1.1e-09 38.4 0.1 0.00024 21.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87723.1 - 1.4e-09 37.4 0.7 0.0027 18.1 0.1 5.2 5 0 0 5 5 5 1 Ankyrin repeat DUF3898 PF13037.6 EAX87723.1 - 0.067 13.3 0.0 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) Rad60-SLD PF11976.8 EAX87724.1 - 0.0051 16.6 0.2 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ALIX_LYPXL_bnd PF13949.6 EAX87724.1 - 0.023 14.0 0.2 0.054 12.8 0.1 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV TFIIE_beta PF02186.15 EAX87724.1 - 0.052 13.8 0.1 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 TFIIE beta subunit core domain PSP PF04046.16 EAX87725.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87726.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TPR_MLP1_2 PF07926.12 EAX87728.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX87728.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX87728.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Gly_rich PF12810.7 EAX87729.1 - 1.8e-22 80.5 12.6 2e-22 80.3 12.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87730.1 - 5.2e-50 170.6 28.1 6.5e-50 170.3 28.1 1.1 1 0 0 1 1 1 1 Glycine rich protein KilA-N PF04383.13 EAX87731.1 - 1.2e-14 54.1 0.1 2.5e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Meiosis_expr PF15163.6 EAX87732.1 - 0.028 15.1 1.2 0.035 14.8 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed DUF365 PF04033.12 EAX87732.1 - 0.044 14.1 0.4 0.059 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Spo12 PF05032.12 EAX87732.1 - 0.82 9.6 10.0 0.17 11.8 2.9 2.9 4 0 0 4 4 4 0 Spo12 family LRR_5 PF13306.6 EAX87733.1 - 6.5e-75 249.2 41.5 1.8e-29 102.3 11.0 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87733.1 - 2.6e-12 46.3 0.4 0.023 14.5 0.1 5.7 5 1 2 7 7 7 3 Leucine rich repeat UPF0231 PF06062.11 EAX87733.1 - 0.2 11.9 0.0 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Pentapeptide_3 PF13576.6 EAX87733.1 - 8.4 6.6 13.9 32 4.8 0.1 5.6 5 2 1 6 6 6 0 Pentapeptide repeats (9 copies) Beach PF02138.18 EAX87734.1 - 1.1e-79 267.8 1.0 1.1e-79 267.8 1.0 2.1 2 0 0 2 2 2 1 Beige/BEACH domain GST_C_3 PF14497.6 EAX87734.1 - 0.18 12.0 0.4 28 5.0 0.1 3.2 2 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Colicin_immun PF09204.10 EAX87734.1 - 1.4 9.5 5.3 3.4 8.3 0.3 3.4 3 0 0 3 3 3 0 Bacterial self-protective colicin-like immunity LRR_5 PF13306.6 EAX87735.1 - 8.1e-47 158.4 25.4 2.5e-26 92.1 10.6 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87735.1 - 1e-07 31.6 0.1 0.013 15.2 0.1 4.6 5 0 0 5 5 5 2 Leucine rich repeat 40S_S4_C PF16121.5 EAX87735.1 - 6.4 6.5 6.0 37 4.1 0.1 3.1 3 0 0 3 3 3 0 40S ribosomal protein S4 C-terminus Colicin_immun PF09204.10 EAX87736.1 - 0.0039 17.7 1.0 0.3 11.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial self-protective colicin-like immunity Ank_2 PF12796.7 EAX87737.1 - 3.2e-53 178.3 15.8 4.2e-16 59.3 0.1 4.5 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX87737.1 - 3.9e-36 122.9 19.5 6.2e-31 106.2 8.0 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX87737.1 - 9.3e-31 105.8 10.5 2.9e-09 37.3 0.2 7.2 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87737.1 - 4.4e-30 103.4 4.6 5.9e-08 32.8 0.0 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX87737.1 - 3.2e-29 100.1 9.3 2.6e-05 24.5 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX87737.1 - 2.8e-24 82.5 10.8 0.00017 21.7 0.0 7.8 8 1 1 9 9 9 4 Ankyrin repeat VWA_3_C PF18571.1 EAX87737.1 - 0.01 15.7 0.0 60 3.6 0.0 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain DUF5641 PF18701.1 EAX87737.1 - 0.16 12.1 0.1 1.2e+02 3.0 0.0 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5641) PapD_N PF00345.20 EAX87740.1 - 0.022 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX87740.1 - 0.061 13.3 0.1 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX87741.1 - 0.018 15.4 0.6 0.023 15.1 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX87741.1 - 1.5 7.8 3.0 1.6 7.7 3.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX87741.1 - 2.4 8.2 6.2 2.5 8.1 6.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX87742.1 - 0.0057 16.7 0.2 0.0076 16.2 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ACP_PD PF04336.12 EAX87743.1 - 0.053 13.9 0.1 0.83 10.1 0.0 2.6 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase Sugar_tr PF00083.24 EAX87744.1 - 3.7e-13 49.2 7.6 4.2e-13 49.0 7.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX87744.1 - 7.7e-06 25.1 15.6 1e-05 24.6 15.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.23 EAX87744.1 - 0.014 15.4 4.5 0.014 15.4 4.5 1.8 1 1 1 2 2 2 0 Membrane-associating domain Sugar_tr PF00083.24 EAX87745.1 - 9.2e-24 84.1 13.1 9.2e-24 84.1 13.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX87745.1 - 2.1e-08 33.5 10.2 6.3e-08 31.9 9.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PAF PF15715.5 EAX87745.1 - 0.00026 21.6 0.6 0.00038 21.0 0.6 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain MFS_3 PF05977.13 EAX87745.1 - 0.0017 16.8 2.3 0.0022 16.5 2.3 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Zip PF02535.22 EAX87745.1 - 0.011 15.0 1.7 0.02 14.1 1.7 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 EAX87745.1 - 0.013 16.0 0.1 0.016 15.6 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 EAX87745.1 - 0.016 14.6 5.0 0.021 14.2 5.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 EAX87745.1 - 0.018 14.7 0.2 0.018 14.7 0.2 1.4 2 0 0 2 2 2 0 FAM176 family O-antigen_lig PF13425.6 EAX87745.1 - 0.034 13.0 1.4 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein HCO3_cotransp PF00955.21 EAX87745.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4834 PF16118.5 EAX87745.1 - 0.24 12.4 0.1 0.24 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RRN3 PF05327.11 EAX87745.1 - 0.84 8.1 5.3 1.1 7.7 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Gelsolin PF00626.22 EAX87746.1 - 3.2e-24 84.6 0.0 1.9e-14 53.3 0.0 2.9 3 0 0 3 3 3 2 Gelsolin repeat Ribosomal_L24e PF01246.20 EAX87746.1 - 0.042 14.1 0.9 1.2 9.4 0.1 2.9 2 1 1 3 3 3 0 Ribosomal protein L24e ETRAMP PF09716.10 EAX87747.1 - 0.018 15.1 2.3 0.04 14.0 2.3 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4625 PF15418.6 EAX87747.1 - 0.025 14.8 4.5 2.5 8.3 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4625) Big_3_3 PF13750.6 EAX87747.1 - 0.027 14.1 0.2 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Fusion_gly PF00523.18 EAX87747.1 - 0.13 10.5 0.6 0.2 9.9 0.6 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF4179 PF13786.6 EAX87747.1 - 0.16 12.5 3.3 13 6.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) NDUFB10 PF10249.9 EAX87749.1 - 0.037 14.5 0.4 12 6.4 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 KilA-N PF04383.13 EAX87751.1 - 6.7e-31 106.4 0.3 1.6e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX87752.1 - 4.3e-157 520.8 13.9 5.3e-157 520.5 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX87752.1 - 0.12 12.8 0.3 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX87752.1 - 0.12 12.8 7.0 2.3 8.8 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAX87754.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX87754.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX87755.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) CAS_CSE1 PF03378.15 EAX87756.1 - 6.6e-32 110.6 1.1 1.5e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EAX87756.1 - 2.7e-26 92.3 11.8 5.2e-26 91.3 11.8 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EAX87756.1 - 1.4e-06 28.1 0.1 6.4e-06 26.0 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_C PF12460.8 EAX87756.1 - 0.0028 16.9 5.8 0.44 9.6 0.1 2.5 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal NitrOD1 PF18549.1 EAX87756.1 - 0.22 11.5 1.8 1.6 8.8 0.1 3.0 3 0 0 3 3 3 0 Nitrosopumilus output domain 1 DUF2767 PF10965.8 EAX87756.1 - 0.44 10.6 1.8 0.69 9.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2767) PTR PF12789.7 EAX87757.1 - 6.5e-32 109.4 45.8 4.6e-31 106.7 18.5 7.2 5 2 1 6 6 6 3 Phage tail repeat like PRA-PH PF01503.17 EAX87759.1 - 0.34 11.4 2.8 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Pox_D5 PF03288.16 EAX87760.1 - 0.00026 21.4 2.7 0.0013 19.1 2.7 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX87760.1 - 0.031 14.9 0.1 0.065 13.9 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX87760.1 - 0.04 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Cdc6_C PF09079.11 EAX87760.1 - 0.083 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX87761.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX87763.1 - 4.2e-07 29.7 2.6 4.2e-07 29.7 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87763.1 - 5e-05 23.6 0.2 0.00038 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX87763.1 - 0.00017 21.6 3.3 0.00044 20.3 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX87763.1 - 0.0002 21.1 0.4 0.34 10.6 0.1 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX87763.1 - 0.00057 19.7 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87763.1 - 0.0014 18.5 0.7 0.0027 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87763.1 - 0.0021 17.8 0.6 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87763.1 - 0.013 15.9 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX87763.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX87763.1 - 0.067 12.8 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX87763.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX87763.1 - 0.082 12.9 0.8 1.1 9.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) AAA PF00004.29 EAX87763.1 - 0.084 13.3 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4588 PF15251.6 EAX87763.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3839 PF12943.7 EAX87764.1 - 2.1e-153 508.7 12.4 2.5e-153 508.4 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX87764.1 - 0.076 13.0 1.6 4.4 7.3 0.0 2.8 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KELK PF15796.5 EAX87764.1 - 2.8 8.5 7.0 2.4 8.7 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX87765.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX87766.1 - 0.0031 17.1 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX87767.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TTL PF03133.15 EAX87768.1 - 8e-55 186.0 1.0 1.6e-52 178.5 1.0 2.1 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 EAX87768.1 - 3e-07 30.6 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_ST PF14397.6 EAX87768.1 - 1.3e-06 27.9 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EAX87768.1 - 1e-05 25.0 0.0 0.16 11.2 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp Acetyltransf_1 PF00583.25 EAX87769.1 - 7.4e-09 35.9 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAX87769.1 - 7.1e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX87769.1 - 0.00043 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EAX87769.1 - 0.0023 17.8 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EAX87769.1 - 0.03 15.0 0.0 0.056 14.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PRMT5 PF05185.16 EAX87770.1 - 1.5e-49 168.2 0.0 2.5e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EAX87770.1 - 1.9e-40 138.6 3.4 1.9e-40 138.6 3.4 1.7 2 0 0 2 2 2 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EAX87770.1 - 0.0082 16.8 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF285 PF03382.14 EAX87770.1 - 0.39 10.5 3.6 0.4 10.5 0.6 2.4 2 1 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Ras PF00071.22 EAX87771.1 - 1.8e-41 141.4 0.0 2.2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87771.1 - 1.7e-27 96.0 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX87771.1 - 7.6e-11 41.8 0.0 1.6e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX87771.1 - 4.6e-06 26.7 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX87771.1 - 1e-05 25.2 0.0 0.0011 18.6 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX87771.1 - 2.5e-05 23.7 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX87771.1 - 0.0006 19.8 0.1 1.7 8.5 0.0 3.0 2 1 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 EAX87771.1 - 0.015 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EAX87771.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX87771.1 - 0.06 12.9 0.1 5.1 6.6 0.0 2.9 2 1 1 3 3 3 0 Ferrous iron transport protein B RAB3GAP2_C PF14656.6 EAX87771.1 - 0.092 11.0 0.0 0.092 11.0 0.0 1.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus AAA_22 PF13401.6 EAX87771.1 - 0.11 12.8 0.2 0.46 10.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 EAX87772.1 - 1.9e-20 72.8 0.0 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87772.1 - 1.2e-11 44.7 0.3 6e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX87772.1 - 7.9e-07 28.9 0.1 0.00044 20.1 0.0 2.4 2 1 0 2 2 2 2 Myb DNA-binding like DUF4106 PF13388.6 EAX87773.1 - 5.5e-271 898.8 17.3 1.2e-270 897.8 17.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) UPF0242 PF06785.11 EAX87774.1 - 0.00079 19.6 8.7 0.0013 18.9 8.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1640 PF07798.11 EAX87774.1 - 0.015 15.3 6.2 0.025 14.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4201 PF13870.6 EAX87774.1 - 0.017 14.8 11.2 0.032 14.0 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 EAX87774.1 - 0.019 14.1 5.2 0.028 13.5 5.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 EAX87774.1 - 0.17 12.2 13.1 1.3 9.3 4.7 2.9 1 1 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 EAX87774.1 - 0.25 11.2 17.1 3 7.7 3.9 2.6 1 1 1 2 2 2 0 Septum formation initiator ERM PF00769.19 EAX87774.1 - 0.41 10.4 13.9 0.63 9.8 13.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 EAX87774.1 - 0.46 10.6 16.4 1.4 9.0 9.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor YabA PF06156.13 EAX87774.1 - 0.5 11.0 9.3 0.35 11.5 6.7 2.0 2 0 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 EAX87774.1 - 0.92 8.8 10.7 1.4 8.2 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med21 PF11221.8 EAX87774.1 - 0.95 9.7 12.1 0.082 13.2 3.2 2.2 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF2968 PF11180.8 EAX87774.1 - 1.4 8.5 8.1 2.1 7.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CENP-H PF05837.12 EAX87774.1 - 1.5 9.2 9.8 2.7 8.4 9.8 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RFC1 PF08519.12 EAX87775.1 - 5.8e-28 98.0 0.2 3.9e-27 95.3 0.0 2.5 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EAX87775.1 - 2e-10 41.2 0.0 6.2e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EAX87775.1 - 5.4e-10 39.5 0.0 3.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 EAX87775.1 - 0.00041 20.6 0.1 0.024 14.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAX87775.1 - 0.00081 19.4 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EAX87775.1 - 0.0009 19.1 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit BRCT_2 PF16589.5 EAX87775.1 - 0.0021 18.4 0.2 0.014 15.7 0.0 2.5 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain AAA_assoc_2 PF16193.5 EAX87775.1 - 0.0022 18.3 0.0 0.0071 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 EAX87775.1 - 0.016 15.6 0.0 0.81 10.0 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 EAX87775.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EAX87775.1 - 0.19 11.4 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Trypan_PARP PF05887.11 EAX87777.1 - 0.32 11.0 9.0 0.49 10.4 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX87777.1 - 2.7 5.5 13.7 3.5 5.2 13.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX87777.1 - 9.9 6.6 6.1 14 6.1 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX87778.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TPR_MLP1_2 PF07926.12 EAX87780.1 - 0.017 15.1 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX87780.1 - 0.062 13.1 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX87780.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PTR PF12789.7 EAX87781.1 - 1.4e-28 98.7 23.3 7.2e-24 83.6 6.5 4.3 4 0 0 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX87781.1 - 0.0032 17.9 10.1 0.39 11.3 0.8 3.4 3 1 0 3 3 3 2 YmaF family DUF4795 PF16043.5 EAX87781.1 - 0.0077 15.9 16.0 0.42 10.2 5.2 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX87781.1 - 0.015 15.1 4.9 0.022 14.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX87781.1 - 0.03 14.8 0.2 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX87781.1 - 0.057 13.1 0.9 2.4 7.8 0.6 2.5 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4116 PF13475.6 EAX87782.1 - 0.011 15.4 0.4 0.036 13.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAX87784.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Metallophos PF00149.28 EAX87785.1 - 2e-35 123.2 0.0 3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX87785.1 - 0.0044 17.4 1.5 0.0075 16.7 0.9 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX87785.1 - 0.0052 17.0 0.0 0.0081 16.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Guanylate_cyc PF00211.20 EAX87786.1 - 9.5e-44 149.2 0.0 1.8e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX87786.1 - 4.1e-16 59.1 0.7 2.6e-15 56.5 0.2 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX87786.1 - 1e-09 38.4 0.1 8.5e-09 35.4 0.1 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EAX87786.1 - 8.2e-07 29.3 0.0 2.2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX87786.1 - 0.0013 18.2 0.2 0.0068 15.9 0.1 2.2 2 0 0 2 2 2 1 Heme NO binding associated PAS_3 PF08447.12 EAX87786.1 - 0.011 16.0 0.0 0.043 14.1 0.0 2.1 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.7 EAX87786.1 - 0.022 14.8 0.0 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 PAS domain PAS_11 PF14598.6 EAX87786.1 - 0.091 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 PAS domain DUF4106 PF13388.6 EAX87787.1 - 1.8e-276 916.9 21.7 1.8e-276 916.9 21.7 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX87787.1 - 0.013 15.8 0.1 0.79 10.1 0.2 2.8 2 0 0 2 2 2 0 Kidney androgen-regulated CarbopepD_reg_2 PF13715.6 EAX87789.1 - 5 7.2 7.8 2.7 8.1 0.6 3.0 3 0 0 3 3 3 0 CarboxypepD_reg-like domain tRNA_anti-like PF12869.7 EAX87790.1 - 0.066 12.8 0.7 8.1 6.0 0.1 2.3 2 0 0 2 2 2 0 tRNA_anti-like Big_7 PF17957.1 EAX87790.1 - 0.099 13.4 0.1 1.3 9.8 0.3 2.6 2 0 0 2 2 2 0 Bacterial Ig domain Imm3 PF14425.6 EAX87791.1 - 0.025 14.6 0.8 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 Immunity protein Imm3 DUF563 PF04577.14 EAX87792.1 - 1.8e-21 77.2 0.5 2.8e-21 76.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TcfC PF16967.5 EAX87792.1 - 0.027 14.0 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 E-set like domain DUF2585 PF10755.9 EAX87792.1 - 0.068 12.9 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) DR2241 PF18069.1 EAX87792.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DR2241 stabilising domain TagA PF12561.8 EAX87793.1 - 0.036 14.5 0.1 0.14 12.5 0.1 2.2 1 1 0 1 1 1 0 ToxR activated gene A lipoprotein domain Vac_Fusion PF02346.16 EAX87793.1 - 0.11 12.2 0.2 0.5 10.0 0.0 2.3 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Pox_A32 PF04665.12 EAX87794.1 - 3.7e-07 29.9 3.3 5.2e-07 29.4 3.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX87794.1 - 0.0044 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX87794.1 - 0.054 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX87794.1 - 0.061 13.1 0.1 0.26 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX87794.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX87794.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX87795.1 - 2.5e-149 495.3 15.2 3.1e-149 495.0 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87795.1 - 0.078 13.4 2.3 0.23 11.9 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX87795.1 - 0.54 10.8 7.7 2.1 8.9 0.6 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX87795.1 - 0.6 10.4 3.4 2.6 8.4 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain Tup_N PF08581.10 EAX87795.1 - 3.4 8.1 7.2 11 6.4 0.1 4.0 3 2 2 5 5 5 0 Tup N-terminal PTR PF12789.7 EAX87798.1 - 5.8e-12 45.5 3.6 7.6e-10 38.7 0.3 5.6 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAX87798.1 - 2.3 7.8 18.5 0.14 11.8 2.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) FragX_IP PF05994.11 EAX87799.1 - 1.9e-192 641.6 19.8 4.9e-191 636.9 19.8 2.2 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family PMT2_N PF17987.1 EAX87799.1 - 0.032 14.4 1.3 1.2 9.3 0.0 3.6 3 0 0 3 3 3 0 Phosphoethanolamine N-methyltransferase 2 N-terminal SIR2 PF02146.17 EAX87799.1 - 0.067 13.1 0.1 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Sir2 family PSP PF04046.16 EAX87800.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX87801.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.5 4 1 1 5 5 5 1 Phage tail repeat like EDR1 PF14381.6 EAX87801.1 - 0.052 13.3 0.4 3.7 7.2 0.1 2.5 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX87801.1 - 0.066 13.7 2.6 0.17 12.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF4116 PF13475.6 EAX87801.1 - 0.099 12.4 0.1 0.36 10.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX87801.1 - 0.97 9.2 11.1 1.1 8.9 10.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX87801.1 - 5.6 6.5 20.8 0.031 13.9 6.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) COX15-CtaA PF02628.15 EAX87803.1 - 0.044 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Rft-1 PF04506.13 EAX87804.1 - 9e-61 206.2 24.9 3.2e-60 204.4 24.9 1.8 1 1 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 EAX87804.1 - 7.5 6.6 32.4 0.44 10.6 15.4 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain RRM_1 PF00076.22 EAX87805.1 - 7.8e-17 60.9 0.0 1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX87805.1 - 0.0003 20.6 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif DNA_topoisoIV PF00521.20 EAX87805.1 - 0.013 14.4 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RRM_Rrp7 PF17799.1 EAX87805.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DUF1866 PF08952.11 EAX87805.1 - 0.21 11.4 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) ATG13 PF10033.9 EAX87806.1 - 2.1e-10 40.7 2.1 6.8e-08 32.5 0.5 2.9 2 1 0 2 2 2 2 Autophagy-related protein 13 eIF_4EBP PF05456.11 EAX87806.1 - 0.077 12.9 0.6 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Dzip-like_N PF13815.6 EAX87807.1 - 1.6e-05 24.9 2.7 1.6e-05 24.9 2.7 3.2 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-met PF12874.7 EAX87807.1 - 0.0065 16.8 0.2 0.019 15.3 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAX87807.1 - 0.013 15.8 0.4 0.013 15.8 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAX87807.1 - 0.024 15.4 1.3 0.063 14.1 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX87807.1 - 0.11 13.0 1.5 0.26 11.8 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAX87807.1 - 3.1 8.2 8.4 0.78 10.1 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3839 PF12943.7 EAX87808.1 - 1.2e-133 444.0 8.4 1.4e-133 443.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX87808.1 - 0.037 14.2 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 Z1 PF10593.9 EAX87808.1 - 0.063 12.8 0.7 0.11 12.0 0.7 1.6 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAX87808.1 - 0.39 11.2 3.0 0.99 9.9 0.8 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase BspA_v PF18220.1 EAX87809.1 - 0.44 10.7 6.7 1.4 9.0 1.2 2.3 2 1 0 2 2 2 0 Adhesin BspA variable domain Pro-NT_NN PF07421.11 EAX87810.1 - 0.012 15.9 0.4 0.012 15.9 0.4 1.0 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor SLBB PF10531.9 EAX87811.1 - 0.033 14.1 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 SLBB domain DUF5439 PF17507.2 EAX87811.1 - 0.042 14.1 0.0 20 5.5 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5439) KilA-N PF04383.13 EAX87812.1 - 2.9e-06 27.1 0.0 4.2e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 KilA-N domain ABC_tran PF00005.27 EAX87814.1 - 1.5e-40 138.8 0.8 9.9e-22 77.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EAX87814.1 - 2e-18 66.2 2.2 2e-18 66.2 2.2 2.8 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 EAX87814.1 - 1.4e-09 37.7 6.3 7e-05 22.4 0.2 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAX87814.1 - 9.9e-08 32.1 7.6 0.11 12.3 2.1 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAX87814.1 - 2.3e-05 24.7 0.0 0.024 14.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAX87814.1 - 2.4e-05 24.3 0.0 0.002 18.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EAX87814.1 - 4.2e-05 23.4 0.1 0.034 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EAX87814.1 - 5.4e-05 22.9 0.3 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 EAX87814.1 - 0.00022 20.5 0.1 0.26 10.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Septin PF00735.18 EAX87814.1 - 0.00026 20.4 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 2 Septin RNA_helicase PF00910.22 EAX87814.1 - 0.00028 21.3 0.0 0.59 10.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 EAX87814.1 - 0.00032 21.1 0.0 0.0083 16.5 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_7 PF12775.7 EAX87814.1 - 0.00045 19.8 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EAX87814.1 - 0.00045 20.2 0.0 1.2 9.1 0.0 2.8 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 EAX87814.1 - 0.00046 20.0 4.6 0.29 10.8 0.0 3.4 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 EAX87814.1 - 0.0025 17.9 0.1 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 EAX87814.1 - 0.0026 17.7 0.1 4.8 7.1 0.0 3.2 3 0 0 3 3 3 2 NTPase AAA PF00004.29 EAX87814.1 - 0.0074 16.7 0.0 12 6.3 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAX87814.1 - 0.0084 16.1 0.0 6.8 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EAX87814.1 - 0.016 15.5 0.0 0.12 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAX87814.1 - 0.02 14.1 0.2 0.54 9.4 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EAX87814.1 - 0.022 15.0 0.2 3.3 8.0 0.2 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EAX87814.1 - 0.023 14.9 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EAX87814.1 - 0.032 13.6 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 EAX87814.1 - 0.077 13.0 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EAX87814.1 - 0.16 11.6 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EAX87814.1 - 0.16 11.4 1.9 4.2 6.8 0.1 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein AAA_23 PF13476.6 EAX87814.1 - 1.7 9.1 12.1 0.96 9.9 0.1 3.6 4 1 0 5 5 3 0 AAA domain DUF1981 PF09324.10 EAX87815.1 - 1.7e-05 24.6 0.7 0.0019 18.0 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1981) Aquarius_N PF16399.5 EAX87815.1 - 0.0053 14.9 3.1 0.22 9.5 0.1 2.0 1 1 0 2 2 2 2 Intron-binding protein aquarius N-terminus Nipped-B_C PF12830.7 EAX87816.1 - 0.073 13.0 0.2 0.087 12.8 0.2 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Ank PF00023.30 EAX87817.1 - 1.9e-86 281.0 26.1 5e-09 36.2 0.1 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 EAX87817.1 - 5.1e-83 272.5 22.7 4.4e-12 46.3 0.0 11.6 4 2 9 13 13 13 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87817.1 - 3.8e-75 248.5 36.7 2.6e-19 69.6 1.9 7.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87817.1 - 6.2e-62 198.2 25.0 1.2e-05 25.3 0.0 12.5 13 1 2 15 15 11 11 Ankyrin repeat Ank_5 PF13857.6 EAX87817.1 - 1.3e-48 162.4 22.1 1.5e-09 37.9 0.7 8.9 4 3 6 11 11 11 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX87817.1 - 1.5e-35 121.0 5.1 1.5e-35 121.0 5.1 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) HEM4 PF02602.15 EAX87817.1 - 0.011 15.1 0.1 0.28 10.5 0.0 2.7 2 2 1 3 3 3 0 Uroporphyrinogen-III synthase HemD DUF3859 PF12975.7 EAX87817.1 - 0.041 13.9 0.1 6.6 6.7 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3859) DUF3718 PF12514.8 EAX87817.1 - 0.1 12.8 13.8 18 5.6 0.1 7.1 8 1 1 9 9 8 0 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX87817.1 - 0.24 11.7 1.8 92 3.4 0.0 4.8 3 1 3 7 7 7 0 Pleckstrin homology domain Peptidase_M16 PF00675.20 EAX87817.1 - 0.51 10.3 6.9 1.8 8.5 0.0 3.9 2 2 1 4 4 4 0 Insulinase (Peptidase family M16) Staphylokinase PF02821.16 EAX87817.1 - 4.1 7.9 9.2 1.1e+02 3.2 0.0 5.5 3 2 5 8 8 8 0 Staphylokinase/Streptokinase family CCDC84 PF14968.6 EAX87817.1 - 5.3 6.6 10.9 24 4.4 0.2 3.9 1 1 1 3 3 3 0 Coiled coil protein 84 Ank PF00023.30 EAX87818.1 - 2.7e-25 87.6 4.0 9.4e-08 32.2 0.1 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX87818.1 - 1.3e-24 86.3 0.8 4.6e-13 49.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87818.1 - 6.2e-20 71.6 2.8 3.7e-12 46.7 1.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87818.1 - 3.7e-19 66.8 0.7 4.8e-05 23.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX87818.1 - 2.7e-14 53.0 4.1 5.1e-05 23.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX87818.1 - 0.00031 20.8 0.6 6.3 7.0 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3718) DUF4107 PF13389.6 EAX87820.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX87821.1 - 2.8e-154 511.6 15.5 3.5e-154 511.2 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87821.1 - 0.04 14.4 1.2 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX87821.1 - 0.29 11.6 7.3 1.8 9.1 0.7 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX87821.1 - 0.93 10.1 6.5 0.44 11.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Ank_2 PF12796.7 EAX87823.1 - 3.1e-31 107.8 3.8 2.2e-11 44.2 0.3 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87823.1 - 7.6e-25 86.7 2.9 1.5e-08 34.8 0.3 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87823.1 - 1e-20 71.6 2.3 4.4e-07 29.7 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX87823.1 - 2.3e-17 63.1 0.3 3.3e-06 27.5 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX87823.1 - 2.4e-17 62.5 0.2 2.7e-06 27.6 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 EAX87823.1 - 1e-07 31.8 1.4 1e-07 31.8 1.4 5.2 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) Atx10homo_assoc PF09759.9 EAX87824.1 - 6e-05 23.0 0.6 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain MMS19_N PF14500.6 EAX87824.1 - 0.028 14.0 0.1 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Adeno_E3_14_5 PF04834.12 EAX87824.1 - 0.1 13.2 0.2 3.5 8.2 0.0 2.3 1 1 1 2 2 2 0 Early E3 14.5 kDa protein Ank_2 PF12796.7 EAX87825.1 - 5.8e-27 94.1 0.0 9.2e-08 32.6 0.0 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87825.1 - 2.4e-10 39.7 0.3 1 10.1 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EAX87825.1 - 7.3e-09 36.0 0.1 0.3 11.7 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX87825.1 - 0.013 15.8 0.1 63 4.1 0.0 4.7 3 2 3 6 6 6 0 Ankyrin repeats (many copies) NPHI_C PF08469.10 EAX87825.1 - 0.038 14.0 2.6 0.097 12.6 0.1 2.4 1 1 0 2 2 2 0 Nucleoside triphosphatase I C-terminal DUF3447 PF11929.8 EAX87825.1 - 0.064 13.2 0.0 0.26 11.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Exonuc_VII_L PF02601.15 EAX87825.1 - 5 6.6 6.7 2.6 7.5 4.2 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit Nup160 PF11715.8 EAX87826.1 - 0.00012 20.8 0.1 0.01 14.5 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.32 EAX87826.1 - 0.0022 18.8 0.0 0.011 16.5 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat CholecysA-Rec_N PF09193.10 EAX87826.1 - 0.1 12.6 0.1 0.41 10.7 0.1 2.1 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal PTR PF12789.7 EAX87827.1 - 4.2e-30 103.6 11.7 4.2e-30 103.6 11.7 4.5 4 1 1 5 5 5 1 Phage tail repeat like YmaF PF12788.7 EAX87827.1 - 0.079 13.5 10.1 1.8 9.2 2.2 3.5 2 1 0 2 2 2 0 YmaF family DUF4116 PF13475.6 EAX87827.1 - 0.16 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) WD40 PF00400.32 EAX87829.1 - 9.2e-15 54.8 11.5 0.00067 20.4 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX87829.1 - 5.8e-10 39.3 0.0 0.0026 18.0 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX87829.1 - 0.001 18.5 0.4 1.1 8.6 0.1 3.2 2 2 0 3 3 3 2 WD40-like domain Utp8 PF10395.9 EAX87829.1 - 0.0057 15.2 0.1 0.71 8.3 0.0 2.4 2 1 0 2 2 2 2 Utp8 family PSII_BNR PF14870.6 EAX87829.1 - 0.0059 15.9 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Adaptin_N PF01602.20 EAX87830.1 - 1.3e-20 73.5 3.4 1.6e-20 73.2 2.4 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EAX87830.1 - 8.1e-08 32.5 8.1 5.1e-07 29.9 0.5 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAX87830.1 - 2.3e-05 24.7 1.0 0.011 16.1 0.1 5.2 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.22 EAX87830.1 - 0.012 15.8 1.7 20 5.8 0.0 4.9 4 1 0 4 4 4 0 HEAT repeat CHAD PF05235.14 EAX87830.1 - 0.054 13.5 0.3 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 CHAD domain VAPB_antitox PF02697.14 EAX87830.1 - 0.1 13.4 0.0 0.52 11.1 0.0 2.3 1 0 0 1 1 1 0 Putative antitoxin RasGEF_N_2 PF14663.6 EAX87830.1 - 0.2 12.1 0.6 2.7 8.4 0.2 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Lipid_DES PF08557.10 EAX87833.1 - 1.6 8.3 4.4 0.46 10.0 1.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) DUF3839 PF12943.7 EAX87834.1 - 2.3e-157 521.6 13.0 2.9e-157 521.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX87834.1 - 0.11 12.9 0.2 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX87834.1 - 0.2 12.1 2.8 4.2 7.9 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3447 PF11929.8 EAX87835.1 - 6.4e-25 86.9 5.9 6.4e-25 86.9 5.9 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX87835.1 - 1.8e-23 82.6 3.8 6.9e-10 39.3 0.2 4.3 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX87835.1 - 7e-23 80.0 2.6 7.4e-09 35.7 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX87835.1 - 3.2e-21 75.7 1.8 2.6e-19 69.6 0.4 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87835.1 - 1.2e-19 70.0 3.0 1.3e-10 41.3 0.6 2.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87835.1 - 3.1e-17 60.9 3.5 1.2e-06 28.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat ThiS-like PF14453.6 EAX87835.1 - 0.0084 16.1 0.5 1 9.5 0.0 2.5 1 1 1 2 2 2 1 ThiS-like ubiquitin MetallophosN PF16371.5 EAX87835.1 - 0.051 13.9 0.1 2 8.7 0.0 2.7 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase BAR PF03114.18 EAX87836.1 - 0.0031 17.2 9.3 0.046 13.4 7.9 2.1 1 1 0 1 1 1 1 BAR domain FRB_dom PF08771.11 EAX87836.1 - 0.12 12.8 1.7 0.75 10.2 0.1 2.5 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain DASH_Duo1 PF08651.10 EAX87836.1 - 0.76 9.6 8.5 0.18 11.6 0.9 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 GrpE PF01025.19 EAX87836.1 - 0.78 9.4 13.7 0.2 11.3 7.1 2.6 3 0 0 3 3 3 0 GrpE MutS_III PF05192.18 EAX87836.1 - 0.92 9.7 8.8 0.19 12.0 1.0 2.2 2 1 0 2 2 2 0 MutS domain III DUF4337 PF14235.6 EAX87836.1 - 2.9 8.0 6.8 4.3 7.4 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CENP-K PF11802.8 EAX87836.1 - 3.4 7.2 18.5 0.81 9.2 8.1 2.4 2 1 0 2 2 2 0 Centromere-associated protein K PCRF PF03462.18 EAX87836.1 - 5.4 6.8 7.8 15 5.4 0.4 2.2 2 0 0 2 2 2 0 PCRF domain NPV_P10 PF05531.12 EAX87837.1 - 1.2 9.7 23.3 1.6 9.2 1.3 5.3 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 EAX87837.1 - 3.5 8.0 26.0 0.72 10.2 1.3 5.9 4 2 0 6 6 6 0 Tup N-terminal APG6_N PF17675.1 EAX87837.1 - 3.9 8.0 32.7 0.54 10.8 8.9 4.8 2 2 2 4 4 4 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 EAX87837.1 - 5.7 7.3 11.1 0.86 9.9 0.5 4.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain GTP-bdg_M PF16360.5 EAX87837.1 - 5.9 7.6 12.3 1.1 9.9 0.6 4.1 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region XhlA PF10779.9 EAX87837.1 - 6 7.1 16.4 7.8 6.8 0.1 4.6 3 2 1 4 4 4 0 Haemolysin XhlA PfkB PF00294.24 EAX87838.1 - 1.1e-39 136.5 0.4 1.5e-39 136.1 0.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3839 PF12943.7 EAX87839.1 - 2.3e-154 511.8 12.6 2.8e-154 511.6 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX87840.1 - 3.9e-07 29.8 3.2 5.5e-07 29.3 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX87840.1 - 0.0039 16.9 0.2 0.005 16.5 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX87840.1 - 0.028 13.9 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX87840.1 - 0.041 13.6 0.1 0.21 11.3 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX87840.1 - 0.059 13.1 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX87840.1 - 0.13 12.3 2.2 1.2 9.2 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX87840.1 - 0.15 12.5 2.4 0.21 12.0 1.0 2.0 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 GPS2_interact PF15784.5 EAX87843.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX87843.1 - 0.075 12.0 0.1 0.07 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MGC-24 PF05283.11 EAX87844.1 - 6.7 7.2 5.8 9.9 6.6 5.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Collagen_bind_2 PF12904.7 EAX87845.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAX87846.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX87846.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX87847.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase BspA_v PF18220.1 EAX87848.1 - 1.5 9.0 5.8 3.2 7.9 1.1 2.3 2 0 0 2 2 2 0 Adhesin BspA variable domain HTH_AraC PF00165.23 EAX87849.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Beach PF02138.18 EAX87850.1 - 2.7e-78 263.1 0.2 7.5e-78 261.7 0.2 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF3932 PF13068.6 EAX87850.1 - 0.034 14.4 1.2 22 5.4 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Laminin_G_3 PF13385.6 EAX87850.1 - 0.045 13.9 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Gp-FAR-1 PF05823.12 EAX87850.1 - 0.56 10.6 4.2 0.22 11.9 0.6 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gly_rich PF12810.7 EAX87851.1 - 1.5e-18 67.6 1.4 1.9e-18 67.3 1.4 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87852.1 - 6.1e-34 118.0 29.6 7.1e-34 117.8 29.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87853.1 - 2e-19 70.5 31.8 2.4e-19 70.2 31.8 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87854.1 - 9.2e-31 107.6 37.1 1.1e-30 107.3 37.1 1.0 1 0 0 1 1 1 1 Glycine rich protein QueF_N PF14819.6 EAX87855.1 - 0.055 13.8 0.4 0.055 13.8 0.4 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Gly_rich PF12810.7 EAX87856.1 - 6.5e-36 124.5 16.0 8.4e-36 124.1 16.0 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87857.1 - 1.9e-31 109.9 39.2 2.3e-31 109.6 39.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87858.1 - 3.4e-33 115.6 18.4 3.8e-33 115.4 18.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX87859.1 - 2e-33 116.3 37.4 2.5e-33 116.0 37.4 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4509 PF14970.6 EAX87861.1 - 0.00025 21.0 0.2 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4509) Ribosomal_S30AE PF02482.19 EAX87861.1 - 0.019 15.8 2.0 0.077 13.8 0.1 2.6 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein HCR PF07111.12 EAX87861.1 - 0.022 12.8 1.3 0.038 12.1 1.2 1.3 1 1 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF3922 PF13059.6 EAX87861.1 - 0.031 14.7 1.1 0.44 11.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) FlxA PF14282.6 EAX87861.1 - 0.09 12.8 0.1 0.09 12.8 0.1 3.0 3 1 0 3 3 3 0 FlxA-like protein HI0933_like PF03486.14 EAX87861.1 - 0.24 10.1 0.9 0.39 9.4 0.9 1.5 1 0 0 1 1 1 0 HI0933-like protein Lipoprotein_20 PF13942.6 EAX87861.1 - 2.9 7.8 7.8 1.6 8.7 0.1 2.8 3 0 0 3 3 3 0 YfhG lipoprotein ZapA PF05164.13 EAX87861.1 - 4.7 7.7 6.7 9.6 6.7 1.1 3.0 2 1 0 2 2 2 0 Cell division protein ZapA Holin_BhlA PF10960.8 EAX87861.1 - 6.4 6.8 8.8 0.56 10.2 0.5 2.9 2 1 0 2 2 2 0 BhlA holin family BPL_N PF09825.9 EAX87861.1 - 7.5 5.5 6.7 11 4.9 6.7 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PH PF00169.29 EAX87862.1 - 1.3e-07 32.1 0.3 6e-07 29.9 0.1 2.2 1 1 1 2 2 2 1 PH domain PH_10 PF15411.6 EAX87862.1 - 0.026 14.8 0.2 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain RRM_1 PF00076.22 EAX87864.1 - 7.4e-21 73.8 0.2 5.3e-12 45.4 0.2 5.2 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX87864.1 - 0.003 17.1 0.2 1.5 8.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EAX87864.1 - 0.005 16.8 0.1 6 6.9 0.0 2.8 2 0 0 2 2 2 2 RL domain DHR-2 PF06920.13 EAX87865.1 - 0.03 13.0 0.2 0.033 12.8 0.2 1.0 1 0 0 1 1 1 0 Dock homology region 2 DpnI_C PF17726.1 EAX87865.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain DHR-2 PF06920.13 EAX87866.1 - 0.03 13.0 0.2 0.033 12.8 0.2 1.0 1 0 0 1 1 1 0 Dock homology region 2 DpnI_C PF17726.1 EAX87866.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain VPS9 PF02204.18 EAX87867.1 - 0.0015 18.7 3.7 0.0029 17.8 0.2 3.0 4 0 0 4 4 4 1 Vacuolar sorting protein 9 (VPS9) domain Herpes_UL14 PF03580.14 EAX87867.1 - 0.15 12.3 1.1 0.32 11.2 0.4 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Holin_BhlA PF10960.8 EAX87867.1 - 1.6 8.7 6.7 16 5.5 0.2 3.6 3 0 0 3 3 3 0 BhlA holin family PDEase_I PF00233.19 EAX87868.1 - 6.3e-20 71.9 0.2 4.7e-19 69.1 0.2 2.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 EAX87868.1 - 1.9e-12 47.6 0.0 8.3e-09 35.9 0.0 4.0 4 0 0 4 4 4 2 GAF domain GAF PF01590.26 EAX87868.1 - 8.5e-11 42.6 0.0 0.0021 18.7 0.0 4.5 4 0 0 4 4 4 3 GAF domain BTB PF00651.31 EAX87868.1 - 0.0031 17.7 2.0 0.0083 16.3 0.4 2.6 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_S24e PF01282.19 EAX87869.1 - 3.9e-29 100.4 0.1 6.4e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAX87869.1 - 0.001 18.9 1.2 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Bromo_TP PF07524.13 EAX87870.1 - 0.023 14.7 0.2 0.076 13.0 0.1 1.9 1 1 1 2 2 2 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EAX87870.1 - 0.084 13.2 0.1 0.12 12.6 0.0 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_MLP1_2 PF07926.12 EAX87871.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX87871.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX87871.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family NDK PF00334.19 EAX87874.1 - 2.1e-40 137.9 0.0 2.4e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1963 PF09234.10 EAX87875.1 - 1.6e-06 28.8 0.1 2.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) IFT46_B_C PF12317.8 EAX87876.1 - 8.3e-74 247.9 0.0 1e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF2110 PF09883.9 EAX87876.1 - 0.16 11.5 0.0 1.1 8.8 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) Pox_A32 PF04665.12 EAX87878.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX87878.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX87878.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX87878.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX87879.1 - 1.4e-33 115.1 0.8 2.7e-33 114.2 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX87880.1 - 9.8e-08 32.5 0.2 1.7e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX87880.1 - 0.012 14.9 0.1 0.02 14.2 0.0 1.4 2 0 0 2 2 2 0 Baculoviridae ME53 Lectin_legB PF00139.19 EAX87880.1 - 0.078 12.5 0.8 0.3 10.6 0.3 1.8 2 0 0 2 2 2 0 Legume lectin domain TBP PF00352.21 EAX87882.1 - 7.6e-49 163.6 0.4 6.2e-24 83.8 0.4 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Surp PF01805.20 EAX87883.1 - 6.9e-22 77.2 1.8 1e-09 38.2 0.2 2.7 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 EAX87883.1 - 4e-13 49.7 18.0 8e-11 42.2 1.4 3.1 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein Adaptin_binding PF10199.9 EAX87883.1 - 0.015 15.9 1.8 0.045 14.3 1.8 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 MOZ_SAS PF01853.18 EAX87884.1 - 1.8e-65 219.9 0.0 2.7e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAX87884.1 - 1.1e-15 56.9 7.6 1.1e-15 56.9 7.6 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAX87884.1 - 1.1e-11 44.4 0.1 2.3e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ank_5 PF13857.6 EAX87885.1 - 1e-29 102.1 5.0 5.1e-06 26.7 0.1 7.2 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX87885.1 - 6.3e-27 94.0 8.2 2.2e-10 41.0 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX87885.1 - 2.6e-26 88.8 2.8 0.0014 19.0 0.1 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 EAX87885.1 - 2.8e-25 88.3 4.8 3.7e-07 30.6 0.0 7.9 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX87885.1 - 1.6e-13 50.4 1.0 0.31 11.6 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat BTB PF00651.31 EAX87885.1 - 0.0084 16.3 0.1 0.031 14.5 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain DUF2939 PF11159.8 EAX87885.1 - 0.51 10.8 2.9 7.8 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) DNA_pol_B_2 PF03175.13 EAX87886.1 - 9.6e-11 41.2 5.1 2.4e-10 39.9 5.1 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4108 PF13390.6 EAX87887.1 - 0.0037 17.2 7.9 0.0046 16.9 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phi-29_GP4 PF05464.11 EAX87887.1 - 0.09 13.1 1.9 0.15 12.3 0.2 2.0 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) DUF3839 PF12943.7 EAX87888.1 - 1.8e-155 515.5 12.5 2.2e-155 515.2 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4168 PF13767.6 EAX87888.1 - 0.014 16.5 1.7 1.4 10.2 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) NTP_transf_6 PF06042.11 EAX87888.1 - 0.12 12.2 0.9 0.37 10.6 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX87888.1 - 0.33 11.4 4.8 5.2 7.6 0.3 3.4 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX87888.1 - 1.6 9.1 4.8 10 6.5 0.1 3.5 4 1 1 5 5 5 0 Tup N-terminal LBR_tudor PF09465.10 EAX87889.1 - 0.00024 20.8 0.3 0.00045 20.0 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX87889.1 - 0.027 14.9 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor PTR PF12789.7 EAX87890.1 - 7.7e-05 22.7 6.1 0.00032 20.7 2.2 4.1 3 1 1 4 4 4 2 Phage tail repeat like EpuA PF11772.8 EAX87890.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PSP PF04046.16 EAX87893.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87894.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87895.1 - 0.096 13.2 0.8 0.22 12.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAX87896.1 - 0.022 14.5 0.6 0.08 12.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Spo12 PF05032.12 EAX87897.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family LRR_8 PF13855.6 EAX87898.1 - 8.8e-40 134.3 37.4 1.5e-10 40.7 2.0 10.6 5 4 6 11 11 11 10 Leucine rich repeat PP2C PF00481.21 EAX87898.1 - 5.9e-38 131.0 0.0 8.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EAX87898.1 - 1e-30 105.3 47.8 5.7e-06 26.6 1.2 12.4 7 4 6 14 14 14 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAX87898.1 - 2.8e-09 36.3 32.1 0.87 9.8 0.0 13.5 15 0 0 15 15 15 2 Leucine Rich repeat LRR_1 PF00560.33 EAX87898.1 - 1.9e-08 33.7 35.5 1 10.1 0.2 13.5 16 2 0 16 16 16 4 Leucine Rich Repeat LRR_9 PF14580.6 EAX87898.1 - 6.1e-06 25.8 12.7 0.093 12.2 0.3 5.4 1 1 4 6 6 6 3 Leucine-rich repeat PP2C_2 PF13672.6 EAX87898.1 - 0.031 13.9 1.0 0.073 12.7 1.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C AlkA_N PF06029.11 EAX87898.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AlkA N-terminal domain LRR_2 PF07723.13 EAX87898.1 - 0.18 12.5 2.3 38 5.2 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1493 PF07377.12 EAX87901.1 - 0.029 14.8 0.7 0.052 14.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX87902.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX87903.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Beach PF02138.18 EAX87904.1 - 1.8e-98 329.3 2.3 3.8e-98 328.3 2.3 1.6 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX87904.1 - 5.2e-20 71.8 6.9 6.5e-20 71.5 4.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAX87904.1 - 5.9e-07 29.5 0.4 2.6e-06 27.5 0.4 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EAX87904.1 - 0.0016 18.6 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pox_A32 PF04665.12 EAX87905.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87905.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87905.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87905.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87905.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87905.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87905.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87905.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87905.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX87905.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX87905.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX87905.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) LRR_5 PF13306.6 EAX87907.1 - 1.2e-131 432.6 59.2 7e-42 142.4 4.4 3.9 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87907.1 - 1.9e-26 91.6 0.0 0.00085 19.0 0.0 8.8 1 1 10 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EAX87907.1 - 5.4e-10 39.4 4.5 0.52 10.8 0.1 7.0 4 3 7 11 11 11 4 Leucine Rich repeats (2 copies) COX6B PF02297.17 EAX87907.1 - 0.004 17.4 0.1 33 4.8 0.0 4.8 3 2 2 5 5 5 0 Cytochrome oxidase c subunit VIb zf_CopZ PF18423.1 EAX87907.1 - 0.12 12.4 1.0 35 4.4 0.0 5.0 5 3 2 7 7 7 0 Zinc binding domain Fimbrial_PilY2 PF14481.6 EAX87907.1 - 0.19 11.4 2.3 4.2 7.1 0.1 3.4 2 1 2 4 4 4 0 Type 4 fimbrial biogenesis protein PilY2 Ras PF00071.22 EAX87909.1 - 1.7e-35 122.0 0.0 2.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX87909.1 - 3.1e-27 95.2 0.0 4.9e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX87909.1 - 2.8e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX87909.1 - 5.9e-10 39.3 0.3 0.00049 20.0 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX87909.1 - 1.5e-08 34.4 0.2 4.5e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX87909.1 - 3.6e-06 27.0 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAX87909.1 - 6.9e-05 22.2 0.9 0.06 12.5 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX87909.1 - 7.2e-05 22.2 0.1 0.0001 21.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EAX87909.1 - 0.00042 20.2 0.5 0.03 14.1 0.1 2.3 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAX87909.1 - 0.0013 18.2 0.1 0.0029 17.1 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX87909.1 - 0.0013 18.3 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EAX87909.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EAX87909.1 - 0.0073 16.1 0.1 0.022 14.5 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EAX87909.1 - 0.025 14.6 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_24 PF13479.6 EAX87909.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX87909.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EAX87909.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PSP PF04046.16 EAX87910.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87911.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX87913.1 - 4e-156 517.6 11.2 5e-156 517.3 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX87913.1 - 1.4 9.4 7.1 1.8 9.1 0.5 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PLAC8 PF04749.17 EAX87914.1 - 9.7e-11 42.5 10.7 1.2e-10 42.3 10.7 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2024 PF09630.10 EAX87914.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) zf-CXXC PF02008.20 EAX87914.1 - 3.2 7.9 17.0 0.3 11.1 1.3 3.0 1 1 1 2 2 2 0 CXXC zinc finger domain DUF3839 PF12943.7 EAX87915.1 - 6.8e-158 523.4 13.2 8.3e-158 523.1 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX87915.1 - 0.12 12.9 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX87915.1 - 0.79 10.1 4.4 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX87915.1 - 1.1 9.7 6.7 3.4 8.2 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX87916.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87916.1 - 0.0017 18.2 0.8 0.011 15.6 0.3 2.4 2 1 0 2 2 2 1 KilA-N domain DUF2719 PF10891.8 EAX87918.1 - 0.092 12.7 1.9 0.11 12.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) CTK3 PF12243.8 EAX87918.1 - 0.13 12.3 4.0 0.094 12.7 1.1 2.3 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 PSP PF04046.16 EAX87919.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87920.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX87922.1 - 2.8e-05 24.1 0.4 2.8e-05 24.1 0.4 4.7 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX87922.1 - 0.06 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX87922.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX87922.1 - 0.3 10.8 10.1 0.29 10.9 8.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF2120 PF09893.9 EAX87922.1 - 1.5 8.9 5.2 1.3 9.2 0.7 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3839 PF12943.7 EAX87923.1 - 2.4e-133 443.0 13.3 6.7e-133 441.6 13.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX87923.1 - 0.064 13.7 2.3 0.1 13.0 0.4 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX87923.1 - 0.076 13.4 0.6 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX87923.1 - 0.22 12.0 8.3 0.77 10.3 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX87924.1 - 4.6e-07 30.3 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX87924.1 - 0.013 15.4 2.7 0.069 13.0 0.9 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAX87924.1 - 0.057 14.4 0.2 0.98 10.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain KleE PF17394.2 EAX87926.1 - 0.012 15.8 1.4 3 8.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein ACP_syn_III_C PF08541.10 EAX87926.1 - 0.059 13.5 0.0 18 5.6 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal zf-CCCH_4 PF18044.1 EAX87926.1 - 0.17 11.7 0.3 0.17 11.7 0.3 4.5 4 0 0 4 4 4 0 CCCH-type zinc finger TMP PF05017.14 EAX87927.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87928.1 - 0.02 15.4 0.7 0.042 14.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX87929.1 - 1.7e-131 428.3 98.2 2.2e-34 117.3 16.2 7.2 3 2 4 7 7 7 5 Phage tail repeat like Apolipoprotein PF01442.18 EAX87929.1 - 0.0052 16.7 4.0 1.4 8.7 0.3 2.3 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain PBP5_C PF07943.13 EAX87929.1 - 0.053 13.8 1.8 0.54 10.5 0.0 3.5 3 1 1 4 4 4 0 Penicillin-binding protein 5, C-terminal domain DUF2785 PF10978.8 EAX87929.1 - 0.12 12.2 12.6 8.3 6.1 0.3 3.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2785) DUF3839 PF12943.7 EAX87930.1 - 8.3e-56 189.1 3.7 9.5e-56 189.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX87930.1 - 0.035 13.6 0.2 0.04 13.4 0.2 1.0 1 0 0 1 1 1 0 Z1 domain MvaI_BcnI PF15515.6 EAX87930.1 - 0.064 13.0 0.8 3.3 7.5 0.0 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family PhoLip_ATPase_C PF16212.5 EAX87931.1 - 1e-33 117.2 16.9 1e-33 117.2 16.9 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EAX87931.1 - 5.1e-10 39.2 1.2 5.1e-10 39.2 1.2 3.6 3 1 0 3 3 3 1 E1-E2 ATPase Vps16_C PF04840.12 EAX87932.1 - 1.6e-06 27.4 1.0 4.8e-06 25.8 0.9 1.8 2 0 0 2 2 2 1 Vps16, C-terminal region Aldo_ket_red PF00248.21 EAX87933.1 - 2.3e-56 191.2 0.0 4.4e-55 187.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family PSP PF04046.16 EAX87934.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX87935.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX87936.1 - 0.085 13.3 0.8 0.18 12.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX87937.1 - 4.5e-60 199.6 43.6 1e-32 111.9 16.5 5.4 2 2 3 5 5 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX87937.1 - 0.049 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX87937.1 - 0.054 13.7 1.1 0.24 11.6 0.0 2.6 3 1 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain PH_TFIIH PF08567.11 EAX87937.1 - 3.9 7.9 7.8 17 5.8 0.2 4.3 2 1 4 6 6 6 0 TFIIH p62 subunit, N-terminal domain Ank_2 PF12796.7 EAX87938.1 - 0.00011 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX87938.1 - 0.00052 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX87938.1 - 0.0016 18.7 0.0 0.0064 16.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX87938.1 - 0.0064 16.9 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EAX87938.1 - 0.032 14.8 0.0 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Thioredoxin_15 PF18403.1 EAX87938.1 - 0.22 11.4 5.1 0.099 12.6 2.4 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain PRP1_N PF06424.12 EAX87938.1 - 0.44 10.9 4.6 0.69 10.3 4.6 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2115 PF09888.9 EAX87938.1 - 3.3 8.2 10.1 3.2 8.2 5.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) MMACHC PF16690.5 EAX87939.1 - 0.048 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family MFS_1 PF07690.16 EAX87940.1 - 4.4e-08 32.4 30.0 1.3e-06 27.6 8.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Syja_N PF02383.18 EAX87941.1 - 2.6e-41 142.0 0.4 2.9e-40 138.6 0.0 2.4 2 1 0 2 2 2 1 SacI homology domain FYVE PF01363.21 EAX87941.1 - 0.0067 16.5 8.7 0.015 15.4 8.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger SDA1 PF05285.12 EAX87942.1 - 1.5e-30 106.8 22.2 2.7e-20 73.1 0.0 2.7 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 EAX87942.1 - 3.6e-05 24.0 0.0 0.00011 22.4 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain SecE PF00584.20 EAX87944.1 - 0.042 13.8 1.2 0.042 13.8 1.2 2.8 3 1 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex UNC-50 PF05216.13 EAX87944.1 - 3 7.4 14.9 10 5.6 14.9 1.9 1 1 0 1 1 1 0 UNC-50 family Vma12 PF11712.8 EAX87944.1 - 5.3 7.1 10.2 0.4 10.7 0.7 2.7 2 2 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase L27_1 PF09058.10 EAX87945.1 - 0.01 15.8 3.3 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 L27_1 Baculo_PEP_C PF04513.12 EAX87945.1 - 0.06 13.4 0.3 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CREPT PF16566.5 EAX87945.1 - 0.068 13.3 1.2 0.13 12.5 0.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX87945.1 - 0.79 9.9 7.2 0.47 10.6 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family VSP PF03302.13 EAX87946.1 - 0.00011 21.2 4.2 0.00021 20.3 4.2 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EAX87946.1 - 0.0014 19.2 1.1 0.0039 17.8 1.0 1.8 1 1 0 1 1 1 1 Small Novel Rich in Cartilage PARM PF17061.5 EAX87946.1 - 0.007 16.5 1.8 0.01 16.0 1.8 1.3 1 0 0 1 1 1 1 PARM RIFIN PF02009.16 EAX87946.1 - 0.012 15.5 1.6 0.02 14.8 1.6 1.4 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX87946.1 - 0.079 13.3 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 EAX87946.1 - 0.28 12.1 1.1 1.7 9.6 0.6 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EAX87946.1 - 1.2 8.9 14.0 2.4 8.0 14.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mem_trans PF03547.18 EAX87947.1 - 7.5e-19 67.4 0.0 1.3e-18 66.6 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Zip PF02535.22 EAX87947.1 - 0.00047 19.5 11.1 0.0069 15.6 11.1 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter SLC12 PF03522.15 EAX87947.1 - 0.71 8.8 13.4 0.94 8.4 13.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 EAX87947.1 - 0.78 9.8 5.8 1.8 8.5 5.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 EAX87947.1 - 1.5 6.8 15.2 2.1 6.4 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 EAX87947.1 - 7.4 4.7 24.0 15 3.8 24.0 1.5 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 EAX87947.1 - 8.3 7.0 11.9 27 5.4 11.9 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Raftlin PF15250.6 EAX87947.1 - 8.4 5.0 14.1 12 4.5 14.1 1.1 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.6 EAX87947.1 - 8.6 6.3 12.6 15 5.5 12.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A HTH_Tnp_4 PF13613.6 EAX87949.1 - 9.2e-05 22.1 0.5 0.00011 21.9 0.5 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease CK_II_beta PF01214.18 EAX87950.1 - 6.8e-42 143.3 0.4 8.5e-42 143.0 0.4 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ARL2_Bind_BART PF11527.8 EAX87950.1 - 0.028 14.5 0.3 0.054 13.6 0.3 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Phage_TAC_1 PF06222.11 EAX87950.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone DNA_primase_lrg PF04104.14 EAX87951.1 - 1.8e-55 188.2 0.0 2.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pox_D5 PF03288.16 EAX87952.1 - 2.1e-05 24.9 0.4 2.1e-05 24.9 0.4 1.5 2 1 0 2 2 2 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX87952.1 - 0.07 13.8 0.1 0.092 13.4 0.1 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX87953.1 - 2.5e-57 192.8 4.2 2.8e-57 192.7 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX87955.1 - 3e-07 30.1 2.4 3e-07 30.1 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX87955.1 - 3.5e-05 24.1 0.2 0.00026 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX87955.1 - 3.6e-05 23.6 0.2 0.4 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX87955.1 - 0.00015 21.8 3.7 0.00037 20.5 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX87955.1 - 0.00041 20.2 0.1 0.00078 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX87955.1 - 0.0011 18.8 0.6 0.0019 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX87955.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX87955.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX87955.1 - 0.073 12.6 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX87955.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX87955.1 - 0.088 12.2 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX87955.1 - 0.096 13.1 0.1 0.78 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX87955.1 - 0.41 10.9 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) FliJ PF02050.16 EAX87956.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX87957.1 - 1e-70 237.1 3.7 1.5e-70 236.5 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX87958.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Annexin PF00191.20 EAX87959.1 - 0.021 14.9 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Annexin Myb_DNA-binding PF00249.31 EAX87961.1 - 1.6e-22 79.4 0.3 1.2e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX87961.1 - 2.1e-15 56.7 0.4 2.6e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX87961.1 - 0.00015 21.8 0.2 0.35 10.9 0.0 2.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX87961.1 - 0.0048 16.8 0.2 0.087 12.7 0.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX87961.1 - 0.024 14.8 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX87961.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Gtr1_RagA PF04670.12 EAX87963.1 - 1.4e-15 57.3 0.2 3.5e-15 56.0 0.2 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX87963.1 - 0.0043 17.0 0.2 0.021 14.7 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 EAX87963.1 - 0.012 15.8 0.0 0.077 13.2 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX87963.1 - 0.021 14.9 0.1 0.093 12.8 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX87963.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EAX87963.1 - 0.14 11.7 0.0 0.7 9.5 0.0 2.1 3 0 0 3 3 3 0 Ras family OST3_OST6 PF04756.13 EAX87964.1 - 2.6e-09 36.8 1.8 3.3e-09 36.5 1.8 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF2627 PF11118.8 EAX87964.1 - 0.0065 17.0 6.0 0.0069 16.9 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2627) Saf_2TM PF18303.1 EAX87964.1 - 4 7.0 5.6 11 5.6 0.3 2.6 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain DUF3839 PF12943.7 EAX87965.1 - 2.9e-155 514.8 12.4 3.7e-155 514.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX87965.1 - 0.083 12.7 0.9 0.27 11.1 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF1689 PF07954.11 EAX87965.1 - 0.088 13.2 1.7 1 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) MitMem_reg PF13012.6 EAX87965.1 - 0.089 13.2 0.4 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Rx_N PF18052.1 EAX87965.1 - 0.38 11.0 3.2 1.6 9.0 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX87965.1 - 1.2 9.7 5.5 2 8.9 0.6 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Csm2_III-A PF03750.13 EAX87966.1 - 0.02 15.8 0.9 0.023 15.5 0.9 1.1 1 0 0 1 1 1 0 Csm2 Type III-A Ribosomal_S6e PF01092.19 EAX87967.1 - 1.5e-48 163.9 0.1 1.5e-48 163.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e MSC PF09402.10 EAX87968.1 - 0.0066 15.9 7.4 0.0066 15.9 7.4 1.7 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain NosD PF05048.13 EAX87969.1 - 0.0019 17.5 7.1 0.0039 16.5 6.9 1.5 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 EAX87969.1 - 0.029 14.9 15.3 0.79 10.3 0.2 5.0 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LolA_2 PF16584.5 EAX87969.1 - 0.1 12.5 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA DUF3161 PF11362.8 EAX87970.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Trypan_PARP PF05887.11 EAX87973.1 - 0.034 14.1 11.6 0.049 13.6 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX87973.1 - 4 7.9 8.5 5.9 7.3 8.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapD_N PF00345.20 EAX87974.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX87974.1 - 0.074 13.0 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Pox_A32 PF04665.12 EAX87976.1 - 2.8e-05 23.7 0.7 2.8e-05 23.7 0.7 1.5 2 0 0 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX87976.1 - 0.0017 18.4 1.4 0.0027 17.7 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX87976.1 - 0.049 13.9 1.9 0.12 12.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Gly_rich PF12810.7 EAX87977.1 - 2.2e-15 57.2 27.8 2.7e-15 57.0 27.8 1.2 1 0 0 1 1 1 1 Glycine rich protein VSP PF03302.13 EAX87977.1 - 8.4e-05 21.6 23.5 0.00067 18.6 23.6 1.9 1 1 1 2 2 2 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EAX87977.1 - 0.17 12.1 21.4 0.064 13.4 9.0 2.2 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich RPM2 PF08579.11 EAX87978.1 - 0.53 10.7 6.4 0.41 11.1 0.7 3.2 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) WD40 PF00400.32 EAX87979.1 - 0.00035 21.3 0.2 0.13 13.1 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat SGL PF08450.12 EAX87979.1 - 0.011 15.4 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region HPS3_N PF14761.6 EAX87979.1 - 0.018 14.6 0.0 0.064 12.8 0.1 1.9 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Ribosomal_L13e PF01294.18 EAX87980.1 - 4.2e-55 186.4 8.4 5.7e-55 186.0 8.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e LRR_5 PF13306.6 EAX87983.1 - 4.5e-120 395.2 78.6 5.1e-35 120.2 8.3 6.1 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX87983.1 - 4e-20 71.3 15.7 0.053 13.3 0.0 10.5 4 2 8 12 12 12 9 Leucine rich repeat DUF4107 PF13389.6 EAX87986.1 - 1.8e-28 99.7 1.6 2e-28 99.6 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Xylo_C PF12529.8 EAX87986.1 - 0.14 11.8 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Xylosyltransferase C terminal Pox_A32 PF04665.12 EAX87989.1 - 1.2e-07 31.5 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF3781 PF12636.7 EAX87990.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX87991.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX87991.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX87993.1 - 7.2e-09 35.0 1.1 1.5e-08 34.0 1.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX87993.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAX87993.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 PapD_N PF00345.20 EAX87994.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX87995.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX87995.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX87996.1 - 0.0047 16.9 0.1 0.0063 16.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX87997.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX87997.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX87998.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 EAX87999.1 - 0.038 14.6 0.0 0.047 14.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88000.1 - 1.9e-31 108.0 10.5 1.3e-08 35.2 0.3 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88000.1 - 4.8e-29 99.5 4.2 1.7e-06 28.2 0.1 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX88000.1 - 9.3e-27 93.4 12.9 1.3e-12 48.1 4.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88000.1 - 3.3e-25 87.8 11.6 2.7e-12 46.7 0.5 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88000.1 - 1.8e-21 73.9 11.8 3.4e-05 23.9 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 EAX88000.1 - 4.3e-21 74.6 7.8 4.3e-21 74.6 7.8 3.9 3 2 0 3 3 3 2 Domain of unknown function (DUF3447) DUF4261 PF14080.6 EAX88000.1 - 0.98 9.6 4.3 6.7 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4261) NAR2 PF16974.5 EAX88001.1 - 9 5.7 5.8 27 4.1 0.3 2.2 1 1 1 2 2 2 0 High-affinity nitrate transporter accessory Ank_2 PF12796.7 EAX88002.1 - 5.5e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88002.1 - 8.3e-05 22.8 0.0 0.00031 21.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88002.1 - 8.5e-05 23.0 0.0 0.00031 21.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX88002.1 - 0.0046 17.3 0.0 0.038 14.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat DUF1043 PF06295.12 EAX88002.1 - 0.015 15.3 2.2 0.03 14.3 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Ank_3 PF13606.6 EAX88002.1 - 0.023 15.2 0.0 0.23 12.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Pinin_SDK_memA PF04696.13 EAX88002.1 - 0.061 13.4 6.8 0.14 12.2 6.8 1.7 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region FliD_N PF02465.18 EAX88002.1 - 2.1 9.1 9.5 0.34 11.6 3.2 2.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PSP PF04046.16 EAX88003.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88004.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat zf-MIZ PF02891.20 EAX88006.1 - 3.2e-13 49.2 2.2 5.5e-13 48.4 2.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EAX88006.1 - 9.6e-10 38.0 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EAX88006.1 - 0.016 15.0 0.6 0.044 13.6 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EAX88006.1 - 0.71 9.8 3.2 1.3 9.0 3.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EAX88006.1 - 4 7.4 5.9 1.7 8.6 3.3 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3447 PF11929.8 EAX88007.1 - 4.4e-24 84.2 17.4 6.1e-23 80.6 4.5 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88007.1 - 7.5e-11 42.5 2.3 1.7e-09 38.1 0.4 2.2 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88007.1 - 1.5e-07 31.1 2.7 0.0039 17.6 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX88007.1 - 7.6e-06 26.1 0.4 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX88007.1 - 9.1e-05 22.9 1.7 0.0012 19.3 0.4 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88007.1 - 0.00012 22.3 1.2 0.089 13.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TPH PF13868.6 EAX88008.1 - 1.8e-42 145.1 176.6 1.8e-42 145.1 176.6 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain LRR_6 PF13516.6 EAX88009.1 - 6.8e-08 32.0 19.4 7.5 6.9 0.2 10.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 EAX88009.1 - 0.00054 20.3 21.8 4.5 7.8 0.1 7.3 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX88009.1 - 0.48 10.2 0.0 0.48 10.2 0.0 5.7 7 2 1 8 8 8 0 Leucine rich repeat TPH PF13868.6 EAX88010.1 - 4.5e-07 28.7 27.0 5.2e-07 28.5 27.0 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DUF5401 PF17380.2 EAX88010.1 - 6.3 4.7 21.7 7.2 4.6 21.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) LsmAD PF06741.13 EAX88010.1 - 6.5 7.4 12.7 0.15 12.7 3.5 2.0 1 1 1 2 2 2 0 LsmAD domain DUF3839 PF12943.7 EAX88012.1 - 2.4e-149 495.4 15.5 3e-149 495.1 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX88012.1 - 0.068 13.0 0.9 0.27 11.1 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX88012.1 - 0.12 12.7 1.5 1.4 9.2 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX88012.1 - 0.12 12.8 0.2 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX88012.1 - 1.1 9.8 7.8 1.9 9.0 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX88014.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88015.1 - 4e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DCX PF03607.17 EAX88016.1 - 4.8e-08 33.0 0.0 7.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Doublecortin DUF2325 PF10087.9 EAX88016.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Beach PF02138.18 EAX88017.1 - 1.2e-88 297.1 0.4 1.8e-88 296.5 0.4 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX88018.1 - 2.5e-16 59.7 7.6 2.5e-16 59.7 7.6 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 EAX88018.1 - 0.0018 18.4 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Bromo_TP PF07524.13 EAX88018.1 - 0.0088 16.0 0.0 0.039 14.0 0.0 2.1 1 0 0 1 1 1 1 Bromodomain associated DUF739 PF05339.11 EAX88018.1 - 0.061 13.5 0.6 0.38 10.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF739) Peptidase_M8 PF01457.16 EAX88019.1 - 2.3e-27 95.9 0.2 3.6e-27 95.2 0.2 1.3 1 1 0 1 1 1 1 Leishmanolysin zf-C3H2C3 PF17122.5 EAX88020.1 - 1.1e-06 28.5 8.0 2.1e-06 27.6 8.0 1.5 1 0 0 1 1 1 1 Zinc-finger zf-RING_11 PF17123.5 EAX88020.1 - 3.1e-06 26.8 2.6 7.4e-06 25.6 2.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EAX88020.1 - 5.5e-06 26.6 8.0 1.2e-05 25.5 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain ANAPC4_WD40 PF12894.7 EAX88020.1 - 8.4e-06 26.0 0.0 0.00012 22.3 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 PF13923.6 EAX88020.1 - 0.0006 19.6 7.8 0.0013 18.5 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX88020.1 - 0.0015 18.5 4.0 0.0059 16.6 4.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX88020.1 - 0.0019 18.1 6.5 0.0049 16.8 6.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EAX88020.1 - 0.0076 15.9 3.3 0.017 14.7 3.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 EAX88020.1 - 0.036 14.5 0.6 0.11 12.9 0.0 2.1 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 EAX88020.1 - 0.058 13.3 4.0 0.27 11.1 4.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Virul_Fac PF10139.9 EAX88020.1 - 0.085 11.1 0.1 0.12 10.5 0.1 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Com_YlbF PF06133.11 EAX88020.1 - 0.1 13.2 0.6 2.6 8.7 0.2 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA zf-rbx1 PF12678.7 EAX88020.1 - 0.12 12.7 5.9 0.34 11.2 5.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40_like PF17005.5 EAX88020.1 - 0.18 11.1 11.1 0.015 14.7 2.1 3.1 3 1 0 3 3 3 0 WD40-like domain Prok-RING_1 PF14446.6 EAX88020.1 - 0.23 11.4 3.5 0.51 10.3 3.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 EAX88020.1 - 0.42 10.5 5.6 0.97 9.3 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX88020.1 - 2.5 8.0 6.7 5.3 7.0 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HSP70 PF00012.20 EAX88021.1 - 4.4e-222 738.5 8.8 5.2e-222 738.3 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX88021.1 - 5.2e-19 68.2 0.4 2.3e-16 59.5 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 EAX88021.1 - 0.00059 20.2 1.6 0.74 10.3 0.1 3.0 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EAX88021.1 - 0.0027 17.5 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EAX88021.1 - 0.018 14.3 0.4 0.11 11.7 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF3153 PF11353.8 EAX88021.1 - 0.078 12.5 0.7 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) DUF1104 PF06518.11 EAX88021.1 - 1.8 9.0 8.6 0.37 11.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) DASH_Spc19 PF08287.11 EAX88021.1 - 8.7 6.2 14.8 0.79 9.6 9.2 2.1 2 0 0 2 2 2 0 Spc19 PMSR PF01625.21 EAX88025.1 - 6.7e-57 192.0 3.2 7.5e-57 191.8 3.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DAHP_snth_FXD PF18152.1 EAX88025.1 - 0.13 12.1 0.1 16 5.4 0.0 2.2 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain ERM PF00769.19 EAX88026.1 - 0.00019 21.3 22.9 0.00019 21.3 22.9 3.3 1 1 1 3 3 3 1 Ezrin/radixin/moesin family HALZ PF02183.18 EAX88026.1 - 0.023 14.9 1.5 0.023 14.9 1.5 6.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper Tup_N PF08581.10 EAX88026.1 - 0.039 14.3 0.8 0.039 14.3 0.8 6.6 5 2 0 5 5 5 0 Tup N-terminal EF-hand_14 PF17959.1 EAX88026.1 - 0.048 14.0 0.1 0.048 14.0 0.1 3.7 3 1 1 4 4 4 0 EF-hand domain DIRP PF06584.13 EAX88026.1 - 0.86 9.8 7.9 0.24 11.6 0.8 3.4 3 0 0 3 3 3 0 DIRP Myc-LZ PF02344.15 EAX88026.1 - 1.3 9.1 9.5 17 5.6 0.0 4.5 3 0 0 3 3 3 0 Myc leucine zipper domain Spc7 PF08317.11 EAX88026.1 - 1.6 7.5 52.5 0.53 9.1 15.4 3.7 2 2 0 3 3 3 0 Spc7 kinetochore protein HrpB7 PF09486.10 EAX88026.1 - 1.8 9.0 29.2 0.16 12.3 3.0 4.8 3 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) DUF2316 PF10078.9 EAX88026.1 - 1.9 8.7 8.1 0.41 10.9 2.9 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Pox_A_type_inc PF04508.12 EAX88026.1 - 8.5 6.4 11.4 0.36 10.7 0.9 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4107 PF13389.6 EAX88027.1 - 3.3e-56 189.9 1.7 4.4e-56 189.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX88028.1 - 1.5e-155 515.7 13.6 1.9e-155 515.4 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX88029.1 - 8.8e-37 127.1 15.0 3.9e-36 124.9 14.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAX88029.1 - 8.4e-06 26.3 0.8 7.5e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 T5orf172 domain DUF2939 PF11159.8 EAX88030.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX88030.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX88031.1 - 0.016 15.2 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAX88033.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88033.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4107 PF13389.6 EAX88034.1 - 8.9e-73 243.8 4.3 1.2e-72 243.4 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Prok-E2_D PF14460.6 EAX88036.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family D DDR PF08841.10 EAX88038.1 - 0.076 12.0 0.1 0.079 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Gly_rich PF12810.7 EAX88039.1 - 4.4e-19 69.4 30.5 4.4e-19 69.4 30.5 1.4 2 0 0 2 2 2 1 Glycine rich protein Gly_rich PF12810.7 EAX88040.1 - 1.5e-29 103.6 39.7 1.9e-29 103.3 39.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Robl_LC7 PF03259.17 EAX88042.1 - 3.2e-11 42.8 0.0 3.5e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF957 PF06117.11 EAX88042.1 - 0.041 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) DUF3139 PF11337.8 EAX88043.1 - 0.018 15.7 2.0 0.03 15.0 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) MFS_Mycoplasma PF07672.13 EAX88043.1 - 0.079 12.2 1.2 0.12 11.6 1.2 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Ank_2 PF12796.7 EAX88044.1 - 2e-43 146.9 16.6 2.6e-17 63.2 1.2 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX88044.1 - 2.5e-38 129.9 5.3 1.3e-37 127.6 5.3 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX88044.1 - 6e-31 106.4 2.6 6.5e-13 48.9 0.1 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX88044.1 - 8.2e-27 92.4 0.0 1.4e-06 28.5 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAX88044.1 - 1.1e-22 77.7 2.1 4.3e-05 23.6 0.0 8.1 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX88044.1 - 2.9e-17 62.5 0.9 1.7e-09 37.7 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF483 PF04467.12 EAX88044.1 - 0.09 12.8 0.9 0.63 10.0 0.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF483) RL PF17797.1 EAX88044.1 - 0.96 9.4 12.4 2.7 8.0 0.1 4.8 3 1 1 5 5 5 0 RL domain Ras PF00071.22 EAX88045.1 - 5.2e-53 178.9 0.7 6.2e-53 178.7 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88045.1 - 4.1e-34 117.4 0.2 7.2e-34 116.6 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88045.1 - 1e-17 64.1 0.1 1.2e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX88045.1 - 8.3e-09 35.5 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX88045.1 - 4.6e-08 32.7 0.2 5.5e-08 32.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX88045.1 - 1.1e-06 28.6 1.4 0.00045 20.2 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EAX88045.1 - 3e-06 26.8 0.1 5.4e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.6 EAX88045.1 - 0.00015 21.6 0.5 0.00019 21.3 0.5 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EAX88045.1 - 0.00016 21.3 0.6 0.00048 19.7 0.1 2.0 2 2 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 EAX88045.1 - 0.00032 20.1 0.1 0.00048 19.5 0.1 1.3 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 EAX88045.1 - 0.00061 19.6 1.0 0.055 13.3 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EAX88045.1 - 0.0021 18.5 0.0 0.0037 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EAX88045.1 - 0.0034 17.9 0.4 0.0052 17.3 0.4 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EAX88045.1 - 0.0046 17.2 0.2 0.025 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAX88045.1 - 0.0083 15.7 0.7 0.26 10.8 0.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_32 PF13654.6 EAX88045.1 - 0.013 14.3 0.1 1.8 7.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 EAX88045.1 - 0.015 14.9 0.3 0.5 10.0 0.3 2.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 EAX88045.1 - 0.016 14.4 1.5 0.77 8.8 0.4 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 EAX88045.1 - 0.02 15.1 0.1 0.036 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 EAX88045.1 - 0.027 14.5 0.1 0.14 12.2 0.1 2.0 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 EAX88045.1 - 0.032 14.3 0.2 0.099 12.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EAX88045.1 - 0.034 14.6 0.1 0.078 13.4 0.0 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAX88045.1 - 0.036 14.1 0.2 0.12 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAX88045.1 - 0.05 13.3 0.2 0.17 11.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAX88045.1 - 0.078 13.4 0.3 0.27 11.6 0.3 2.1 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EAX88045.1 - 0.09 12.7 0.2 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 NTPase Pox_A32 PF04665.12 EAX88045.1 - 0.092 12.2 0.5 0.64 9.4 0.4 2.3 1 1 1 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 EAX88045.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EAX88045.1 - 0.11 12.0 0.1 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EAX88045.1 - 0.14 12.1 0.0 0.67 9.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EAX88045.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Calreticulin PF00262.18 EAX88047.1 - 8.6e-55 186.1 11.5 1.5e-41 142.5 1.7 2.1 1 1 1 2 2 2 2 Calreticulin family Ank_4 PF13637.6 EAX88048.1 - 2.6e-33 113.9 3.0 4.8e-10 39.8 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88048.1 - 3.6e-33 114.0 1.0 2e-13 50.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88048.1 - 6e-29 99.7 0.1 1e-07 32.1 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88048.1 - 7e-25 84.4 0.6 0.00094 19.5 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX88048.1 - 1.1e-20 73.1 5.0 0.0032 17.9 0.0 6.7 6 1 1 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX88048.1 - 0.0025 17.7 0.9 1.6 8.7 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX88048.1 - 0.062 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase T5orf172 PF10544.9 EAX88049.1 - 2.6e-07 31.1 0.3 5.3e-07 30.1 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX88049.1 - 0.14 12.9 0.3 0.37 11.5 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Rhodanese PF00581.20 EAX88050.1 - 1.8e-12 47.7 0.0 2.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF2304 PF10066.9 EAX88051.1 - 0.32 11.2 2.4 6.8 7.0 0.2 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Pox_A_type_inc PF04508.12 EAX88051.1 - 5.3 7.1 16.7 0.85 9.6 0.4 6.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF1192 PF06698.11 EAX88051.1 - 9.4 6.4 19.4 14 5.8 1.0 6.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1192) GPS2_interact PF15784.5 EAX88052.1 - 0.023 15.1 0.6 0.03 14.8 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAX88052.1 - 0.038 14.4 2.2 0.038 14.4 2.2 1.2 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Trypan_PARP PF05887.11 EAX88053.1 - 0.036 14.1 8.2 0.056 13.4 8.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX88054.1 - 0.022 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX88055.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX88055.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX88055.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ResIII PF04851.15 EAX88057.1 - 5.7e-05 23.2 2.6 0.00011 22.2 2.6 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAX88057.1 - 6.2e-05 23.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX88057.1 - 0.00043 20.1 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX88057.1 - 0.00073 19.4 0.7 0.0022 17.8 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX88057.1 - 0.0054 16.5 0.3 0.25 11.1 0.0 2.6 1 1 1 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EAX88057.1 - 0.0077 16.6 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX88057.1 - 0.05 13.0 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAX88057.1 - 0.084 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA PF00004.29 EAX88057.1 - 0.1 13.0 0.0 0.37 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX88057.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX88057.1 - 0.24 11.7 4.5 5.3 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Pox_A32 PF04665.12 EAX88058.1 - 0.00013 21.5 0.4 0.00015 21.3 0.4 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Epimerase_2 PF02350.19 EAX88058.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase KilA-N PF04383.13 EAX88059.1 - 5.7e-44 148.5 0.6 1.1e-43 147.6 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX88059.1 - 0.061 13.9 0.0 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 Parathyroid hormone family DUF3839 PF12943.7 EAX88060.1 - 4.3e-152 504.4 13.2 5.4e-152 504.1 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX88060.1 - 0.066 13.1 1.2 0.25 11.2 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX88060.1 - 6.4 7.3 7.1 2.5 8.6 0.8 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Motile_Sperm PF00635.26 EAX88061.1 - 2.7e-06 27.2 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF724 PF05266.14 EAX88061.1 - 0.0062 16.4 1.9 0.0089 15.9 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF4254 PF14063.6 EAX88061.1 - 0.03 14.2 1.7 0.051 13.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Kinesin PF00225.23 EAX88062.1 - 2.1e-107 358.9 0.2 2.1e-107 358.9 0.2 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAX88062.1 - 1.4e-23 83.5 0.0 1.4e-23 83.5 0.0 2.7 2 1 0 2 2 2 1 Microtubule binding THRAP3_BCLAF1 PF15440.6 EAX88062.1 - 0.29 10.1 24.3 0.43 9.5 24.3 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF966 PF06136.13 EAX88062.1 - 0.74 9.5 18.0 1.3 8.7 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PTR PF12789.7 EAX88063.1 - 2.8e-38 129.8 27.8 2.1e-32 110.9 13.7 5.5 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX88063.1 - 0.064 13.0 0.9 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Ank_4 PF13637.6 EAX88064.1 - 7e-97 316.7 18.6 6e-12 45.8 0.1 14.8 4 1 11 15 15 15 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88064.1 - 1.1e-93 308.0 68.1 4.8e-14 52.7 1.4 8.8 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88064.1 - 1.5e-93 303.4 13.9 1.2e-06 28.7 0.0 13.2 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 EAX88064.1 - 2.1e-73 233.5 22.1 2.9e-05 24.1 0.0 15.0 17 0 0 17 17 15 12 Ankyrin repeat Ank_5 PF13857.6 EAX88064.1 - 1.4e-71 235.6 22.7 2.6e-11 43.5 0.3 10.0 5 3 6 11 11 11 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88064.1 - 5.8e-37 125.5 8.0 5.8e-37 125.5 8.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) P2_Phage_GpR PF06891.11 EAX88064.1 - 0.0082 16.2 0.4 69 3.5 0.0 4.8 4 0 0 4 4 4 0 P2 phage tail completion protein R (GpR) ATP13 PF12921.7 EAX88064.1 - 0.093 12.6 2.1 0.45 10.4 0.5 3.0 2 0 0 2 2 2 0 Mitochondrial ATPase expression SAB PF04382.13 EAX88064.1 - 0.51 10.4 22.0 96 3.2 0.0 9.1 11 0 0 11 11 11 0 SAB domain DUF3718 PF12514.8 EAX88064.1 - 0.58 10.3 33.5 13 6.1 0.2 10.2 10 2 1 11 11 11 0 Protein of unknown function (DUF3718) DUF5064 PF16703.5 EAX88064.1 - 1.7 9.1 8.1 3.1 8.3 0.0 4.5 2 1 4 6 6 5 0 Domain of unknown function (DUF5064) ThiS-like PF14453.6 EAX88064.1 - 2.1 8.4 30.6 3.5 7.7 0.6 7.4 5 3 2 7 7 7 0 ThiS-like ubiquitin CCDC84 PF14968.6 EAX88064.1 - 9.8 5.7 23.9 11 5.5 5.9 3.0 1 1 2 3 3 3 0 Coiled coil protein 84 GAT PF03127.14 EAX88065.1 - 4.2e-05 23.8 27.8 5.6e-05 23.4 2.0 5.1 3 2 1 4 4 4 2 GAT domain Med21 PF11221.8 EAX88065.1 - 0.0015 18.8 2.2 0.0015 18.8 2.2 4.0 3 2 0 4 4 4 1 Subunit 21 of Mediator complex TACC_C PF05010.14 EAX88065.1 - 0.0088 15.9 10.7 0.0088 15.9 10.7 3.3 3 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 EAX88065.1 - 0.011 15.8 21.9 0.25 11.4 0.9 4.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EAX88065.1 - 0.032 14.5 15.1 0.38 11.1 1.2 4.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3053 PF11254.8 EAX88065.1 - 0.079 12.5 8.6 0.077 12.6 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) SAG PF04092.13 EAX88065.1 - 0.081 13.7 0.8 0.2 12.5 0.8 1.7 1 0 0 1 1 1 0 SRS domain Syntaxin_2 PF14523.6 EAX88065.1 - 0.5 10.8 27.0 0.45 10.9 6.3 4.4 3 2 1 4 4 4 0 Syntaxin-like protein UPF0242 PF06785.11 EAX88065.1 - 0.81 9.8 28.6 0.11 12.6 3.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EAX88065.1 - 0.89 9.1 22.6 1.7 8.2 11.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EAX88065.1 - 1 9.4 21.7 0.43 10.6 3.9 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EAX88065.1 - 1 8.4 23.0 0.74 8.8 1.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 EAX88065.1 - 1.8 8.9 24.0 0.53 10.6 1.3 3.9 3 2 1 4 4 4 0 Tup N-terminal DUF3800 PF12686.7 EAX88065.1 - 2.1 9.0 6.2 4e+02 1.7 6.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) AATF-Che1 PF13339.6 EAX88065.1 - 2.2 9.0 22.3 3.2 8.4 3.4 3.2 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2730 PF10805.8 EAX88065.1 - 3.7 7.7 11.0 1.8 8.7 0.2 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) DUF2400 PF09674.10 EAX88065.1 - 3.9 7.4 11.4 6.1 6.8 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) CAMP_factor PF07373.11 EAX88065.1 - 4 7.0 14.6 1.7 8.2 0.4 3.8 4 0 0 4 4 4 0 CAMP factor (Cfa) DUF4618 PF15397.6 EAX88065.1 - 4.2 6.7 30.8 2.2 7.6 2.6 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EAX88065.1 - 5.3 7.5 37.9 0.42 11.0 13.8 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 EAX88065.1 - 6 6.1 28.3 0.055 12.8 6.2 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EAX88065.1 - 7.5 5.7 20.0 3.8 6.7 0.9 3.1 2 1 1 3 3 3 0 TMPIT-like protein KASH_CCD PF14662.6 EAX88065.1 - 8 6.2 39.9 0.25 11.1 21.8 3.8 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH COG2 PF06148.11 EAX88065.1 - 9.6 6.3 24.5 5.8 7.0 1.6 4.7 2 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_60s PF00428.19 EAX88066.1 - 1e-15 58.1 6.1 1.2e-15 57.9 6.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2880 PF11082.8 EAX88066.1 - 0.96 9.8 8.2 2 8.8 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Ribosomal_L27A PF00828.19 EAX88067.1 - 1.7e-21 77.2 0.0 2.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sec15 PF04091.12 EAX88068.1 - 2e-11 43.9 2.8 6e-11 42.3 2.8 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like LemA PF04011.12 EAX88068.1 - 0.0092 15.8 2.3 0.033 14.1 1.0 2.6 2 1 0 2 2 2 1 LemA family Vps51 PF08700.11 EAX88068.1 - 0.48 10.5 11.2 0.95 9.6 1.0 5.0 4 1 0 4 4 4 0 Vps51/Vps67 Sec8_exocyst PF04048.14 EAX88068.1 - 6.8 6.6 13.4 4.6 7.1 4.3 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF5344 PF17279.2 EAX88068.1 - 8.4 7.0 9.8 0.92 10.1 0.7 3.7 3 1 1 4 4 4 0 Family of unknown function (DUF5344) DUF563 PF04577.14 EAX88069.1 - 0.00093 19.4 0.0 0.0016 18.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) cEGF PF12662.7 EAX88070.1 - 0.01 15.7 2.7 0.023 14.6 2.7 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.27 EAX88070.1 - 0.037 14.3 6.4 0.075 13.3 6.4 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.7 EAX88070.1 - 0.58 10.4 9.6 2.3 8.5 7.8 2.7 2 1 0 2 2 2 0 EGF domain hEGF PF12661.7 EAX88070.1 - 2.3 9.0 7.6 6.8 7.5 7.6 1.9 1 1 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 EAX88070.1 - 2.4 8.6 7.5 12 6.4 7.5 2.0 1 1 0 1 1 1 0 EGF-like domain SNAP PF14938.6 EAX88071.1 - 0.022 14.2 1.2 0.13 11.7 0.7 2.1 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 EAX88071.1 - 1.9 8.4 4.6 0.9 9.5 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MULE PF10551.9 EAX88073.1 - 4.1e-10 39.9 0.2 1e-09 38.6 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX88073.1 - 0.012 15.3 0.2 0.056 13.2 0.1 1.9 1 1 1 2 2 2 0 Transposase Transposase_mut PF00872.18 EAX88073.1 - 0.015 14.2 0.2 0.015 14.2 0.2 1.7 2 0 0 2 2 2 0 Transposase, Mutator family Ribosomal_L32e PF01655.18 EAX88076.1 - 8.5e-36 122.7 0.0 1.1e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Trypan_PARP PF05887.11 EAX88078.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88078.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MULE PF10551.9 EAX88079.1 - 4.3e-11 43.1 0.9 1.2e-10 41.7 0.9 1.8 1 0 0 1 1 1 1 MULE transposase domain L27_1 PF09058.10 EAX88079.1 - 0.093 12.7 5.0 0.29 11.1 0.0 3.4 3 1 0 3 3 3 0 L27_1 HALZ PF02183.18 EAX88080.1 - 0.0007 19.8 0.5 0.0007 19.8 0.5 6.8 5 3 1 6 6 6 2 Homeobox associated leucine zipper ATG16 PF08614.11 EAX88080.1 - 0.0085 16.3 4.7 0.0085 16.3 4.7 3.7 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EAX88080.1 - 0.0089 16.1 5.0 0.0089 16.1 5.0 5.1 1 1 3 4 4 4 1 Modifier of rudimentary (Mod(r)) protein KASH_CCD PF14662.6 EAX88080.1 - 0.34 10.7 67.4 0.048 13.5 10.9 3.8 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Catalase-rel PF06628.12 EAX88080.1 - 0.37 11.0 2.6 40 4.5 0.0 3.5 3 0 0 3 3 3 0 Catalase-related immune-responsive APG6_N PF17675.1 EAX88080.1 - 4 8.0 56.4 0.37 11.3 8.4 4.6 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF1843 PF08898.10 EAX88080.1 - 4.5 7.9 7.6 2.5 8.7 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) ERM PF00769.19 EAX88080.1 - 9.3 6.0 46.9 2.8 7.7 8.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cnn_1N PF07989.11 EAX88081.1 - 0.0018 18.4 18.1 0.0018 18.4 18.1 6.3 3 2 1 4 4 4 1 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 EAX88081.1 - 0.0085 15.4 11.5 0.0085 15.4 11.5 5.5 1 1 3 5 5 5 3 Protein of unknown function (DUF3450) Lebercilin PF15619.6 EAX88081.1 - 0.013 15.2 6.5 0.013 15.2 6.5 4.4 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 EAX88081.1 - 0.63 8.1 81.3 1.3 7.1 35.5 2.7 1 1 1 2 2 2 0 HOOK protein Peptidase_C54 PF03416.19 EAX88082.1 - 1.7e-46 158.8 0.0 2.4e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 CAP18_C PF12153.8 EAX88082.1 - 0.17 11.8 0.1 14 5.6 0.1 2.6 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) LIM PF00412.22 EAX88084.1 - 1.9e-35 120.8 83.5 9.3e-08 32.2 13.2 5.2 5 0 0 5 5 5 5 LIM domain FANCI_HD1 PF14679.6 EAX88086.1 - 0.043 13.8 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 FANCI helical domain 1 T2SSF PF00482.23 EAX88086.1 - 0.058 13.3 0.0 1.5 8.8 0.0 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F FLYWCH PF04500.16 EAX88088.1 - 0.043 13.9 4.0 0.077 13.1 4.0 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX88088.1 - 0.069 13.9 1.1 0.19 12.5 1.1 1.7 1 1 0 1 1 1 0 FAR1 DNA-binding domain Myb_DNA-binding PF00249.31 EAX88089.1 - 9.3e-28 96.2 0.7 4.8e-15 55.5 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88089.1 - 2.9e-17 62.6 0.1 6.7e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX88089.1 - 1.5e-05 25.0 0.2 0.16 12.0 0.1 3.0 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX88089.1 - 0.011 15.5 1.2 2.6 8.0 0.1 3.3 1 1 2 3 3 3 0 Myb DNA-binding like VirK PF06903.12 EAX88090.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 VirK protein Guanylate_cyc PF00211.20 EAX88091.1 - 3.4e-45 153.9 0.1 7.4e-45 152.8 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX88091.1 - 2.9e-14 53.2 2.6 2e-13 50.5 0.2 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX88091.1 - 2e-06 27.8 0.0 6.5e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX88091.1 - 5.4e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX88091.1 - 0.01 15.3 0.1 0.025 14.0 0.1 1.7 1 0 0 1 1 1 0 Heme NO binding associated VPS11_C PF12451.8 EAX88092.1 - 0.14 12.4 0.5 0.26 11.6 0.5 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CrgA PF06781.12 EAX88093.1 - 0.041 14.0 0.2 0.067 13.3 0.1 1.5 1 1 1 2 2 2 0 Cell division protein CrgA ROK PF00480.20 EAX88094.1 - 2e-08 34.1 0.0 2.2e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 ROK family Myb_DNA-binding PF00249.31 EAX88095.1 - 1.2e-24 86.3 0.0 2.1e-12 47.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88095.1 - 5.2e-16 58.7 2.1 2.2e-12 47.0 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX88095.1 - 0.003 17.7 0.6 0.12 12.5 0.1 2.5 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX88095.1 - 0.0042 16.9 6.2 0.21 11.5 0.4 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Gemini_AL1_M PF08283.11 EAX88095.1 - 0.018 15.1 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Geminivirus rep protein central domain WIYLD PF10440.9 EAX88095.1 - 0.098 12.5 0.3 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_4 PF13837.6 EAX88095.1 - 0.11 12.9 4.9 0.58 10.6 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DNA_pol_B_2 PF03175.13 EAX88096.1 - 4.4e-10 39.0 3.4 4.4e-10 39.0 3.4 2.4 1 1 2 3 3 3 1 DNA polymerase type B, organellar and viral PhaP_Bmeg PF09602.10 EAX88096.1 - 0.058 13.3 0.1 0.62 10.0 0.1 2.2 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Isy1 PF06246.12 EAX88096.1 - 0.11 12.1 0.7 0.23 11.0 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX88096.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter HTH_32 PF13565.6 EAX88097.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain KIAA1430 PF13879.6 EAX88098.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue WD40 PF00400.32 EAX88102.1 - 5.4e-08 33.4 4.0 1.1 10.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX88102.1 - 0.0018 18.6 0.0 1.1 9.7 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain UQ_con PF00179.26 EAX88103.1 - 7.9e-37 126.0 0.0 9.6e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAX88103.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Noc2 PF03715.13 EAX88104.1 - 4.9e-11 42.4 1.0 4.9e-11 42.4 1.0 1.5 2 0 0 2 2 2 1 Noc2p family FCH PF00611.23 EAX88104.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Bac_DNA_binding PF00216.21 EAX88104.1 - 1.4 9.2 8.1 20 5.5 0.0 4.4 4 0 0 4 4 4 0 Bacterial DNA-binding protein PSP PF04046.16 EAX88106.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP BsuPI PF12690.7 EAX88107.1 - 0.51 10.4 2.7 18 5.4 2.7 2.5 1 1 0 1 1 1 0 Intracellular proteinase inhibitor HSCB_C PF07743.13 EAX88108.1 - 1.1e-15 57.9 4.9 2.3e-15 56.8 4.9 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EAX88108.1 - 0.00028 20.9 3.1 0.00041 20.4 0.2 2.5 3 0 0 3 3 3 1 DnaJ domain AAA_9 PF12781.7 EAX88108.1 - 0.021 14.0 3.6 0.036 13.2 3.6 1.4 1 0 0 1 1 1 0 ATP-binding dynein motor region PAP_central PF04928.17 EAX88108.1 - 0.063 12.2 1.1 0.092 11.7 1.1 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain HscB_4_cys PF18256.1 EAX88108.1 - 0.11 12.3 2.2 0.22 11.3 2.2 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Cytochrome_cB PF11783.8 EAX88108.1 - 0.21 11.4 2.2 0.39 10.6 2.2 1.4 1 0 0 1 1 1 0 Cytochrome c bacterial Ank_2 PF12796.7 EAX88109.1 - 2.5e-44 149.8 0.1 5.2e-16 59.0 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88109.1 - 2.4e-36 123.7 2.0 6.8e-12 45.7 0.2 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88109.1 - 4.4e-28 94.2 2.0 7.1e-06 26.0 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX88109.1 - 5.6e-28 96.6 4.6 6.8e-08 32.6 0.2 5.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88109.1 - 4.8e-27 93.2 1.3 3.7e-07 30.3 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat HAP1_N PF04849.13 EAX88109.1 - 0.045 13.0 1.4 0.068 12.4 1.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Mid2 PF04478.12 EAX88111.1 - 0.016 15.1 0.2 0.033 14.0 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX88111.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 EAX88111.1 - 0.31 11.9 2.9 0.81 10.6 2.9 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX88111.1 - 0.57 10.1 1.6 1.1 9.2 1.6 1.5 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 EAX88112.1 - 1.8e-05 24.6 0.2 5.3e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor PT PF04886.12 EAX88112.1 - 0.00027 20.4 71.2 0.11 12.1 12.6 4.4 1 1 1 2 2 2 1 PT repeat TMEM154 PF15102.6 EAX88112.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 EAX88112.1 - 0.034 13.9 4.3 0.064 13.0 4.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EAX88112.1 - 0.23 11.4 4.1 0.66 9.9 4.1 1.7 1 0 0 1 1 1 0 Syndecan domain Ras PF00071.22 EAX88114.1 - 6.6e-45 152.6 0.5 7.8e-45 152.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88114.1 - 1.6e-29 102.6 0.0 2.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88114.1 - 2.2e-18 66.3 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX88114.1 - 5.3e-06 26.4 0.1 0.039 13.9 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX88114.1 - 9.4e-06 25.3 0.3 0.00081 19.0 0.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX88114.1 - 1.5e-05 24.5 0.1 2.9e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88114.1 - 2.5e-05 24.3 0.0 3.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX88114.1 - 0.00041 19.8 0.2 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX88114.1 - 0.00056 20.3 0.5 0.0049 17.3 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAX88114.1 - 0.0068 16.4 0.1 0.061 13.3 0.0 2.2 1 1 2 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EAX88114.1 - 0.015 15.8 0.0 0.041 14.3 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAX88114.1 - 0.021 14.6 0.1 0.069 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAX88114.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX88114.1 - 0.041 14.1 0.0 0.061 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 EAX88114.1 - 0.044 13.1 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_22 PF13401.6 EAX88114.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAX88114.1 - 0.069 12.9 0.1 0.22 11.3 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX88114.1 - 0.087 12.3 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Mito_fiss_reg PF05308.11 EAX88115.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX88115.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DDE_Tnp_ISL3 PF01610.17 EAX88116.1 - 0.0011 18.7 0.2 0.0026 17.5 0.2 1.6 1 0 0 1 1 1 1 Transposase FAS_N PF17828.1 EAX88118.1 - 0.0066 16.5 0.2 0.01 15.8 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta FliJ PF02050.16 EAX88118.1 - 0.05 13.8 0.2 0.074 13.3 0.2 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Peptidase_C14 PF00656.22 EAX88118.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Caspase domain EF-hand_10 PF14788.6 EAX88119.1 - 0.022 14.6 0.1 0.083 12.8 0.1 2.0 1 0 0 1 1 1 0 EF hand Zn_ribbon_2 PF12674.7 EAX88119.1 - 0.069 13.8 0.4 4 8.2 0.0 3.5 2 1 1 3 3 3 0 Putative zinc ribbon domain YmgB PF10798.8 EAX88120.1 - 0.033 14.0 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF3839 PF12943.7 EAX88121.1 - 2.8e-152 505.0 12.6 3.4e-152 504.7 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88121.1 - 0.047 14.1 1.9 0.21 12.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88121.1 - 0.055 13.9 5.8 0.85 10.1 0.3 3.5 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX88121.1 - 0.14 12.0 1.3 0.33 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX88121.1 - 1.8 9.1 6.7 0.56 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX88121.1 - 2.2 8.6 5.7 11 6.4 0.1 3.6 3 2 2 5 5 5 0 Tup N-terminal FtsJ PF01728.19 EAX88123.1 - 1.5e-36 126.1 0.0 2.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ras PF00071.22 EAX88124.1 - 3.7e-51 173.0 0.1 4.5e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88124.1 - 1.3e-34 119.0 0.0 1.8e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88124.1 - 1.2e-17 64.0 0.0 1.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX88124.1 - 6.8e-08 32.3 0.0 3e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX88124.1 - 2.1e-06 27.8 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX88124.1 - 2.3e-06 27.6 0.1 0.063 13.2 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX88124.1 - 3.5e-06 26.6 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAX88124.1 - 0.016 14.8 0.1 1.2 8.6 0.1 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EAX88124.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EAX88124.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein CH PF00307.31 EAX88125.1 - 4.2e-66 220.0 3.0 1.3e-21 76.8 0.2 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EAX88125.1 - 0.00022 21.0 0.3 0.01 15.7 0.0 3.2 3 1 1 4 4 4 1 CAMSAP CH domain Plasmid_parti PF01672.16 EAX88125.1 - 0.025 15.2 0.3 0.086 13.5 0.1 2.0 2 0 0 2 2 2 0 Putative plasmid partition protein HMG_CoA_synt_N PF01154.17 EAX88125.1 - 0.06 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal FmrO PF07091.11 EAX88126.1 - 0.051 13.1 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) HisKA_7TM PF16927.5 EAX88126.1 - 0.059 13.4 0.2 0.091 12.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Pkinase PF00069.25 EAX88127.1 - 2.3e-12 46.9 2.0 5.5e-12 45.6 2.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAX88127.1 - 0.00029 20.3 0.7 0.00063 19.2 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EAX88127.1 - 0.0066 15.8 0.3 0.015 14.6 0.3 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX88127.1 - 0.027 14.4 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rrf2 PF02082.20 EAX88128.1 - 0.045 14.1 0.1 0.061 13.7 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator AAA_16 PF13191.6 EAX88129.1 - 1.1e-06 29.1 0.0 2.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX88129.1 - 2.5e-05 24.5 0.0 9.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAX88129.1 - 0.00032 20.7 3.0 0.00065 19.7 0.3 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EAX88129.1 - 0.00048 20.2 0.5 0.0071 16.4 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EAX88129.1 - 0.00088 19.0 0.0 0.0029 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAX88129.1 - 0.0052 16.7 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 EAX88129.1 - 0.0059 17.0 0.0 0.016 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EAX88129.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX88129.1 - 0.023 15.1 0.1 0.24 11.8 0.0 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAX88129.1 - 0.037 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EAX88129.1 - 0.042 13.4 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAX88129.1 - 0.07 12.3 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EAX88129.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4116 PF13475.6 EAX88130.1 - 0.0096 15.6 0.4 0.022 14.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) Pox_A32 PF04665.12 EAX88133.1 - 7.8e-07 28.8 3.0 7.8e-07 28.8 3.0 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX88133.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX88133.1 - 5.5e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX88133.1 - 0.00018 21.6 3.9 0.0004 20.4 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX88133.1 - 0.0006 19.6 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX88133.1 - 0.0012 18.6 0.5 0.0023 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX88133.1 - 0.01 15.5 3.3 0.012 15.2 0.2 2.3 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX88133.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX88133.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX88133.1 - 0.084 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX88133.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX88133.1 - 0.35 11.1 4.8 5.1 7.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TMP PF05017.14 EAX88136.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Hpr_kinase_N PF02603.16 EAX88138.1 - 0.067 13.2 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase N terminus Ank_4 PF13637.6 EAX88139.1 - 3.4e-08 33.9 0.1 1.7e-07 31.7 0.0 2.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88139.1 - 3.4e-06 27.5 0.0 1.2e-05 25.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88139.1 - 0.00018 21.8 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88139.1 - 0.00022 21.4 0.1 0.01 16.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAX88139.1 - 0.0026 18.1 0.1 0.0082 16.6 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Hpr_kinase_N PF02603.16 EAX88140.1 - 0.034 14.2 0.1 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase N terminus Ank_2 PF12796.7 EAX88141.1 - 1.8e-11 44.5 0.5 6.2e-10 39.5 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88141.1 - 8e-11 42.3 0.2 1.2e-06 29.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88141.1 - 2.9e-07 30.6 0.1 0.00097 19.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88141.1 - 1.1e-06 28.4 0.1 0.012 16.0 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX88141.1 - 0.0019 18.6 0.0 0.044 14.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat DUF1759 PF03564.15 EAX88141.1 - 0.03 14.2 2.1 0.041 13.8 0.4 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) DUF535 PF04393.13 EAX88142.1 - 0.0094 15.2 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF535) MULE PF10551.9 EAX88145.1 - 5.4e-06 26.7 0.0 2.6e-05 24.6 0.0 2.2 2 1 1 3 3 3 1 MULE transposase domain TetR_C_19 PF17924.1 EAX88145.1 - 1.7 9.2 9.9 0.13 12.8 1.8 2.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DDE_1 PF03184.19 EAX88147.1 - 1.6e-05 24.7 0.0 1.8e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4895 PF16236.5 EAX88147.1 - 0.21 11.4 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4895) DDE_Tnp_4 PF13359.6 EAX88148.1 - 2.1e-25 89.2 0.0 3.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX88148.1 - 5.6e-12 45.8 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX88148.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MULE PF10551.9 EAX88149.1 - 2.4e-11 43.9 0.1 4.9e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX88149.1 - 0.011 16.1 0.7 0.27 11.7 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5365) DUF4065 PF13274.6 EAX88149.1 - 0.12 13.2 0.5 2.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) FLYWCH PF04500.16 EAX88149.1 - 0.28 11.3 4.7 0.55 10.4 4.7 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain CbiD PF01888.17 EAX88150.1 - 0.054 12.8 0.1 0.054 12.8 0.1 1.0 1 0 0 1 1 1 0 CbiD DNAJ_related PF12339.8 EAX88150.1 - 0.075 13.3 0.0 0.086 13.1 0.0 1.0 1 0 0 1 1 1 0 DNA-J related protein DUF4107 PF13389.6 EAX88151.1 - 0.026 14.7 1.5 0.059 13.5 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4107) DUF4375 PF14300.6 EAX88152.1 - 7.4 6.9 9.9 36 4.6 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) DUF3574 PF12098.8 EAX88155.1 - 0.13 12.1 0.4 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Amidase02_C PF12123.8 EAX88157.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88158.1 - 3.9e-30 105.2 2.5 7.3e-30 104.3 2.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Shisa PF13908.6 EAX88160.1 - 1.2e-05 25.7 12.2 1.2e-05 25.7 12.2 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 EAX88160.1 - 9e-05 22.4 1.1 0.0002 21.3 1.1 1.6 1 0 0 1 1 1 1 Transmembrane 52 Baculo_F PF12259.8 EAX88160.1 - 0.0054 15.3 1.2 0.0082 14.7 1.2 1.2 1 0 0 1 1 1 1 Baculovirus F protein DUF3481 PF11980.8 EAX88160.1 - 0.0099 15.6 2.8 0.024 14.3 2.8 1.6 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein EphA2_TM PF14575.6 EAX88160.1 - 0.032 15.1 2.3 0.088 13.7 2.3 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 EAX88160.1 - 0.1 12.7 2.0 0.12 12.4 0.5 1.9 1 1 0 1 1 1 0 Podoplanin Prominin PF05478.11 EAX88160.1 - 1 7.2 9.5 1.5 6.7 9.5 1.1 1 0 0 1 1 1 0 Prominin DUF4834 PF16118.5 EAX88160.1 - 2.2 9.3 6.2 0.37 11.8 0.2 2.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) Cnd1 PF12717.7 EAX88161.1 - 0.21 11.6 8.6 0.093 12.8 1.1 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 KIAA1430 PF13879.6 EAX88162.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX88163.1 - 1.2 9.8 4.2 2.7 8.7 4.2 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF846 PF05832.12 EAX88164.1 - 0.046 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Topoisom_I_N PF02919.15 EAX88166.1 - 0.56 9.7 11.6 0.69 9.4 11.6 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RR_TM4-6 PF06459.12 EAX88166.1 - 0.69 9.7 11.2 0.74 9.6 11.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 EAX88166.1 - 1.1 9.8 5.5 0.97 9.9 5.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 EAX88166.1 - 1.8 8.3 9.1 1.9 8.2 9.1 1.1 1 0 0 1 1 1 0 Connexin CMS1 PF14617.6 EAX88166.1 - 2 7.7 12.0 2 7.7 12.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Eapp_C PF10238.9 EAX88166.1 - 2.1 8.4 8.1 2.2 8.4 8.1 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein AP-5_subunit_s1 PF15001.6 EAX88166.1 - 3.2 7.7 7.5 3.6 7.5 7.5 1.0 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 EIIBC-GUT_N PF03612.14 EAX88166.1 - 3.2 7.5 6.7 3.2 7.5 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2956 PF11169.8 EAX88166.1 - 4.6 7.5 15.8 6.7 7.0 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Neur_chan_memb PF02932.16 EAX88166.1 - 5.1 7.1 6.6 5.9 6.9 6.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 EAX88166.1 - 5.2 6.6 21.6 5.7 6.5 21.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec62 PF03839.16 EAX88166.1 - 5.9 6.3 9.6 5.7 6.4 9.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 EAX88166.1 - 6.1 5.5 6.1 5.9 5.5 6.1 1.0 1 0 0 1 1 1 0 Presenilin U79_P34 PF03064.16 EAX88166.1 - 6.7 6.0 16.7 6.2 6.1 16.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 OTCace PF00185.24 EAX88167.1 - 1e-52 178.4 0.0 1.5e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EAX88167.1 - 1.7e-43 148.2 0.5 2.5e-43 147.7 0.5 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ank_2 PF12796.7 EAX88168.1 - 5.8e-115 376.1 67.0 7.3e-19 68.2 1.9 10.2 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88168.1 - 2e-110 356.8 32.8 6.7e-09 35.8 0.1 16.3 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 EAX88168.1 - 5.8e-106 345.6 38.6 7.2e-13 48.8 0.3 16.1 3 1 13 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88168.1 - 8.7e-84 265.4 43.2 4.7e-06 26.5 0.0 17.6 18 0 0 18 18 17 14 Ankyrin repeat Ank_5 PF13857.6 EAX88168.1 - 7.1e-69 227.0 34.5 9.7e-09 35.3 0.0 11.3 4 2 8 14 14 14 11 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88168.1 - 1.2e-35 121.3 5.5 1.2e-35 121.3 5.5 8.5 3 2 6 9 9 9 2 Domain of unknown function (DUF3447) WYL PF13280.6 EAX88168.1 - 5.1e-06 26.6 0.0 3.2 7.8 0.0 5.3 3 1 3 6 6 6 2 WYL domain MetallophosN PF16371.5 EAX88168.1 - 0.00016 21.8 0.0 11 6.4 0.0 5.2 3 2 2 6 6 6 1 N terminal of Calcineurin-like phosphoesterase Arg_repressor PF01316.21 EAX88168.1 - 0.0002 21.1 1.4 1.1e+02 2.6 0.0 7.7 10 0 0 10 10 10 0 Arginine repressor, DNA binding domain DUF5535 PF17687.1 EAX88168.1 - 0.0068 16.6 0.0 41 4.4 0.0 5.1 2 1 3 7 7 7 0 Family of unknown function (DUF5535) Mic1 PF07035.12 EAX88168.1 - 0.042 13.6 7.9 6 6.6 0.0 5.7 4 2 3 7 7 7 0 Colon cancer-associated protein Mic1-like CCDC84 PF14968.6 EAX88168.1 - 0.62 9.6 15.9 0.28 10.8 3.0 3.7 1 1 0 3 3 3 0 Coiled coil protein 84 Transmemb_17 PF09799.9 EAX88169.1 - 7.4e-17 61.9 10.5 7.4e-17 61.9 10.5 2.0 1 1 1 2 2 2 1 Predicted membrane protein FixQ PF05545.11 EAX88169.1 - 0.38 10.8 0.1 0.38 10.8 0.1 3.3 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Cpn10 PF00166.21 EAX88170.1 - 1.2e-25 89.4 0.1 1.3e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GDWWSH PF15667.5 EAX88170.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function with motif GDWWSH Ribosomal_S4 PF00163.19 EAX88171.1 - 8e-07 29.9 0.8 1.8e-06 28.8 0.7 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EAX88171.1 - 1e-06 28.3 0.1 2.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 S4 domain LKAAEAR PF15478.6 EAX88173.1 - 0.0018 18.5 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif YMF19 PF02326.15 EAX88173.1 - 0.049 14.4 1.5 0.2 12.4 1.4 2.1 1 1 0 1 1 1 0 Plant ATP synthase F0 DDE_Tnp_ISL3 PF01610.17 EAX88174.1 - 8.6e-06 25.6 0.3 2.3e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 Transposase Pkinase_Tyr PF07714.17 EAX88175.1 - 5e-12 45.6 0.0 6.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX88175.1 - 1.6e-09 37.6 0.0 2.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAX88175.1 - 0.00088 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like VPS9 PF02204.18 EAX88176.1 - 7.7e-11 42.1 0.5 7.7e-11 42.1 0.5 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF3447 PF11929.8 EAX88177.1 - 2e-22 78.9 1.3 2e-22 78.9 1.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX88177.1 - 4.7e-13 49.4 2.1 6.4e-06 26.6 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88177.1 - 1e-10 42.0 2.8 1.2e-07 32.2 0.3 3.7 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88177.1 - 1.1e-08 35.1 0.3 7.3e-07 29.3 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88177.1 - 7.4e-08 32.1 2.6 0.0059 17.0 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 EAX88177.1 - 1.3e-06 28.5 0.2 0.51 10.9 0.0 5.0 5 1 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EAX88178.1 - 1.5e-97 320.4 38.3 4.6e-17 62.4 0.1 9.5 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88178.1 - 1.4e-67 222.9 1.6 6.5e-11 42.3 0.1 12.2 3 2 10 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88178.1 - 3.4e-62 206.1 2.6 3.3e-11 43.5 0.0 14.0 3 1 14 17 17 16 15 Ankyrin repeats (many copies) Ank PF00023.30 EAX88178.1 - 6.2e-59 194.0 13.9 6.4e-05 23.2 0.1 15.0 15 0 0 15 15 15 11 Ankyrin repeat Ank_3 PF13606.6 EAX88178.1 - 4.1e-55 177.3 3.5 0.0003 21.0 0.1 16.6 16 0 0 16 16 16 11 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX88178.1 - 2.4e-11 43.3 10.7 4.4e-11 42.5 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX88178.1 - 2.8e-09 36.7 9.2 5.5e-09 35.8 9.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3447 PF11929.8 EAX88178.1 - 4.7e-08 32.9 3.1 0.18 11.8 0.4 5.9 6 1 0 6 6 6 2 Domain of unknown function (DUF3447) zf-RING_5 PF14634.6 EAX88178.1 - 0.0016 18.3 10.6 0.0038 17.1 10.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAX88178.1 - 0.014 15.7 10.6 0.031 14.6 10.6 1.6 1 0 0 1 1 1 0 Ring finger domain ArlS_N PF18719.1 EAX88178.1 - 0.27 11.4 1.1 38 4.5 0.1 3.5 4 0 0 4 4 4 0 ArlS sensor domain zf-C3HC4_2 PF13923.6 EAX88178.1 - 7.4 6.5 11.4 16 5.5 11.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Y_phosphatase2 PF03162.13 EAX88179.1 - 0.011 15.3 0.3 0.018 14.6 0.3 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX88179.1 - 0.012 14.9 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 tRNA_synt_1c_R1 PF04558.15 EAX88179.1 - 0.012 15.6 0.4 0.041 13.9 0.0 1.9 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 S-AdoMet_synt_C PF02773.16 EAX88180.1 - 5.3e-68 227.3 0.0 1.6e-67 225.8 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAX88180.1 - 4.1e-45 152.9 0.0 6.8e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAX88180.1 - 5.2e-42 142.6 0.3 1e-41 141.6 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EAX88180.1 - 0.005 15.7 0.2 1.6 7.4 0.0 2.1 2 0 0 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) DUF5623 PF18536.1 EAX88182.1 - 0.091 13.0 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX88182.1 - 0.18 11.7 5.6 0.15 12.0 2.9 2.1 2 1 0 2 2 2 0 Spo12 family Baculo_PEP_C PF04513.12 EAX88184.1 - 7.3e-06 26.1 42.1 0.13 12.3 5.4 5.8 1 1 4 6 6 6 6 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EAX88184.1 - 0.00035 20.6 0.3 0.00035 20.6 0.3 5.5 2 2 4 6 6 6 1 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EAX88184.1 - 0.00089 16.9 18.2 0.00089 16.9 18.2 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 EAX88184.1 - 0.014 15.6 1.5 0.014 15.6 1.5 5.4 3 1 2 6 6 6 0 Fibrinogen alpha/beta chain family HsbA PF12296.8 EAX88184.1 - 0.13 12.7 20.4 0.41 11.1 0.2 5.5 1 1 5 6 6 6 0 Hydrophobic surface binding protein A MtrB PF05440.12 EAX88184.1 - 0.16 12.4 0.3 4 7.9 0.0 3.0 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Prominin PF05478.11 EAX88184.1 - 0.19 9.7 31.0 0.22 9.5 2.8 3.4 2 1 1 3 3 3 0 Prominin DASH_Dam1 PF08653.10 EAX88184.1 - 0.43 10.4 12.6 4.4 7.2 0.0 5.4 7 0 0 7 7 7 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 EAX88184.1 - 1.7 9.1 23.7 9.5 6.7 0.2 7.3 5 2 0 5 5 5 0 Flagella accessory protein C (FlaC) TMP PF05017.14 EAX88186.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAX88187.1 - 0.097 12.9 0.3 28 5.0 0.0 2.8 3 0 0 3 3 3 0 P22AR C-terminal domain Pox_A32 PF04665.12 EAX88192.1 - 1.4e-06 27.9 3.6 1.5e-06 27.9 2.6 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX88192.1 - 0.00038 20.7 0.2 0.003 17.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX88192.1 - 0.00067 19.7 2.8 0.0014 18.7 2.5 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX88192.1 - 0.001 18.9 0.1 0.0027 17.5 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX88192.1 - 0.001 18.8 1.1 0.0056 16.4 0.5 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX88192.1 - 0.0017 18.1 0.2 0.33 10.7 0.0 2.7 1 1 2 3 3 3 1 IstB-like ATP binding protein AAA_11 PF13086.6 EAX88192.1 - 0.02 14.7 0.6 0.038 13.8 0.6 1.6 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX88192.1 - 0.047 13.5 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_19 PF13245.6 EAX88192.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain DUF4108 PF13390.6 EAX88194.1 - 2.4e-62 209.1 6.1 2.7e-62 208.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX88195.1 - 2.3e-05 24.8 3.4 0.00018 21.9 3.4 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX88195.1 - 0.018 15.6 0.2 0.034 14.8 0.2 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX88195.1 - 0.077 13.0 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF1493 PF07377.12 EAX88196.1 - 0.034 14.6 0.7 0.075 13.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX88197.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Pkinase PF00069.25 EAX88199.1 - 4.7e-70 236.0 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88199.1 - 3.2e-35 121.6 0.0 4.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX88199.1 - 1.3e-07 32.1 0.1 2.4e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX88199.1 - 5.5e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 EAX88199.1 - 1.7e-05 25.4 0.1 3.5e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.22 EAX88199.1 - 0.1 12.2 0.0 4.5 6.8 0.0 2.3 1 1 0 2 2 2 0 RIO1 family UCH PF00443.29 EAX88200.1 - 1.6e-39 136.0 0.0 7.1e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX88200.1 - 2.1e-10 40.7 4.6 9e-08 32.1 0.0 3.1 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAX88200.1 - 3.6e-06 27.2 0.6 3.6e-06 27.2 0.6 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Mut7-C PF01927.16 EAX88200.1 - 0.039 14.1 3.3 0.4 10.8 0.5 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-Di19 PF05605.12 EAX88200.1 - 0.11 12.8 0.5 0.11 12.8 0.5 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RRPl_C4 PF17026.5 EAX88200.1 - 0.2 11.8 0.0 0.2 11.8 0.0 3.3 3 2 1 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type PHD PF00628.29 EAX88200.1 - 4 7.4 6.9 60 3.6 0.1 3.8 4 0 0 4 4 4 0 PHD-finger Ras PF00071.22 EAX88201.1 - 1.6e-36 125.4 0.0 1.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88201.1 - 4.9e-28 97.8 0.0 8.4e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88201.1 - 6.1e-12 45.3 0.0 7.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX88201.1 - 0.0012 18.7 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX88201.1 - 0.0044 16.6 0.0 0.0087 15.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX88201.1 - 0.0064 15.9 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88201.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EAX88201.1 - 0.054 13.3 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAX88201.1 - 0.054 12.9 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_ligase_OB PF03120.16 EAX88201.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain V_ATPase_I PF01496.19 EAX88202.1 - 4.4 5.1 8.4 6.3 4.6 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCLC PF05934.11 EAX88202.1 - 4.6 5.8 7.2 6.1 5.4 7.2 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4455 PF14643.6 EAX88203.1 - 8e-97 324.8 28.5 8e-97 324.8 28.5 4.2 3 1 0 4 4 4 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 EAX88203.1 - 2.7e-52 177.5 4.5 2.7e-52 177.5 4.5 5.7 5 3 1 6 6 6 1 Domain of unknown function (DUF4456) Apolipoprotein PF01442.18 EAX88203.1 - 0.0054 16.6 23.5 0.018 14.9 0.2 6.1 4 2 0 4 4 4 1 Apolipoprotein A1/A4/E domain Sam68-YY PF16568.5 EAX88203.1 - 0.99 10.2 4.4 3 8.7 0.6 3.1 2 0 0 2 2 2 0 Tyrosine-rich domain of Sam68 DUF1024 PF06260.12 EAX88203.1 - 2.7 8.3 6.4 1.4 9.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1024) ApoO PF09769.9 EAX88203.1 - 5.7 6.9 17.0 0.34 10.9 0.6 5.9 4 3 2 6 6 6 0 Apolipoprotein O PA26 PF04636.13 EAX88205.1 - 0.044 12.7 8.0 0.059 12.3 8.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) UPF0242 PF06785.11 EAX88205.1 - 0.11 12.7 20.5 0.19 11.9 20.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WDCP PF15390.6 EAX88205.1 - 0.17 10.2 8.3 0.19 10.1 8.3 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Zip PF02535.22 EAX88205.1 - 0.21 10.8 4.4 0.25 10.5 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.18 EAX88205.1 - 0.44 8.9 2.6 0.48 8.8 2.6 1.1 1 0 0 1 1 1 0 Membrane transport protein ALMT PF11744.8 EAX88205.1 - 1.3 7.8 6.3 1.7 7.4 6.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GAGA_bind PF06217.12 EAX88205.1 - 1.5 9.0 11.2 2.2 8.5 11.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family APG6_N PF17675.1 EAX88205.1 - 1.5 9.3 24.9 2.4 8.7 24.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PTPlike_phytase PF14566.6 EAX88205.1 - 2 8.5 15.5 5.4 7.1 15.5 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Membralin PF09746.9 EAX88205.1 - 4.4 6.3 9.2 5.8 5.8 9.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein SH3_9 PF14604.6 EAX88207.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAX88207.1 - 1.3e-07 31.1 0.0 2.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAX88207.1 - 7.9e-06 25.5 0.0 0.00049 19.7 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain hSH3 PF14603.6 EAX88207.1 - 0.015 15.7 0.1 0.85 10.1 0.1 3.2 2 1 1 3 3 3 0 Helically-extended SH3 domain Pox_A32 PF04665.12 EAX88209.1 - 4.8e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX88209.1 - 0.0059 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX88209.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 tRNA_bind PF01588.20 EAX88211.1 - 3.1e-11 43.2 0.1 4.9e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain LRR_5 PF13306.6 EAX88213.1 - 5.7e-100 330.2 58.0 3e-24 85.4 8.5 8.0 3 2 3 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88213.1 - 1.3e-10 40.9 7.1 1.3 8.8 0.0 10.0 12 2 1 13 13 13 5 Leucine rich repeat LRR_5 PF13306.6 EAX88214.1 - 2.3e-34 118.1 19.9 2.8e-18 66.1 2.9 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88214.1 - 9e-13 47.8 2.6 8.9e-05 22.2 0.0 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX88214.1 - 0.0023 18.3 15.9 0.31 11.5 0.9 4.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) RE_Bsp6I PF09504.10 EAX88214.1 - 0.073 12.7 2.1 0.66 9.5 0.2 2.6 2 1 1 3 3 3 0 Bsp6I restriction endonuclease LRR_5 PF13306.6 EAX88215.1 - 2.3e-107 354.1 63.4 7.6e-20 71.2 0.7 7.2 1 1 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88215.1 - 6.6e-26 89.9 0.8 0.00047 19.9 0.0 10.7 8 4 3 11 11 11 6 Leucine rich repeat LRR_4 PF12799.7 EAX88215.1 - 2.3e-10 40.5 11.9 0.76 10.3 0.2 8.9 9 1 0 9 9 9 4 Leucine Rich repeats (2 copies) Gly_rich PF12810.7 EAX88216.1 - 6.8e-41 140.8 29.9 8.8e-41 140.4 29.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Tubulin_C PF03953.17 EAX88217.1 - 3.1e-31 108.2 0.0 3.7e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain MULE PF10551.9 EAX88218.1 - 4.1e-05 23.9 0.1 7.6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain UCH PF00443.29 EAX88219.1 - 6e-38 130.8 0.2 6e-38 130.8 0.2 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX88219.1 - 1.7e-08 34.5 0.6 2.2e-05 24.2 0.6 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX88219.1 - 0.00081 18.9 1.1 0.51 9.8 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Snapin_Pallidin PF14712.6 EAX88219.1 - 0.023 15.1 1.6 0.12 12.8 1.6 2.3 1 0 0 1 1 1 0 Snapin/Pallidin SAM_KSR1 PF13543.6 EAX88219.1 - 0.065 13.4 2.2 0.14 12.3 0.8 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Phage_TAC_12 PF12363.8 EAX88219.1 - 0.1 13.0 2.6 60 4.1 0.1 4.2 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC GluRS_N PF18466.1 EAX88219.1 - 0.11 12.9 0.1 21 5.6 0.0 3.3 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain GAT PF03127.14 EAX88219.1 - 0.35 11.2 4.5 0.33 11.3 0.1 3.4 4 0 0 4 4 4 0 GAT domain Myotub-related PF06602.14 EAX88219.1 - 0.41 9.5 7.8 0.39 9.6 1.7 2.6 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain PTR PF12789.7 EAX88220.1 - 1e-08 35.1 1.6 1e-08 35.1 1.6 3.4 2 1 1 3 3 3 1 Phage tail repeat like DUF1192 PF06698.11 EAX88220.1 - 0.026 14.6 2.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Bcr-Abl_Oligo PF09036.10 EAX88220.1 - 0.036 14.1 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF167 PF02594.16 EAX88220.1 - 0.06 13.5 0.5 3 8.0 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 SlyX PF04102.12 EAX88220.1 - 0.23 12.1 1.7 3.4 8.3 0.4 2.8 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 EAX88220.1 - 0.39 10.8 11.6 0.23 11.5 9.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 EAX88220.1 - 1.1 9.9 10.0 0.12 13.0 3.2 2.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF3839 PF12943.7 EAX88221.1 - 5e-155 514.0 13.6 6.4e-155 513.7 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX88221.1 - 0.014 15.2 0.6 0.04 13.8 0.3 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX88221.1 - 0.039 14.4 0.6 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX88221.1 - 0.049 13.9 0.7 16 5.9 0.0 3.5 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX88221.1 - 0.053 14.0 2.1 1.7 9.2 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX88221.1 - 0.15 12.7 0.3 0.15 12.7 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX88221.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.0 4 1 0 4 4 4 0 PRD domain Pox_A32 PF04665.12 EAX88223.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX88223.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX88223.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX88223.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX88223.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX88223.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX88223.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX88223.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX88223.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX88223.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX88223.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX88223.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX88223.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX88224.1 - 0.66 9.9 3.7 1.4 8.9 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX88225.1 - 8.7e-58 194.3 5.0 9.7e-58 194.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX88226.1 - 8.8e-157 519.8 13.5 1.1e-156 519.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX88226.1 - 0.22 12.1 4.7 1.2 9.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX88226.1 - 0.56 10.7 7.7 2 8.9 1.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX88226.1 - 0.59 10.4 2.6 2.9 8.2 0.0 3.0 2 2 0 2 2 2 0 Rx N-terminal domain PTR PF12789.7 EAX88228.1 - 1.2e-09 38.1 24.9 4.3e-09 36.3 11.7 5.1 3 2 1 4 4 4 2 Phage tail repeat like YmaF PF12788.7 EAX88228.1 - 8.8 6.9 13.9 29 5.3 5.1 3.4 2 2 0 2 2 2 0 YmaF family DUF1493 PF07377.12 EAX88229.1 - 0.076 13.5 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX88230.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88231.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PQ-loop PF04193.14 EAX88233.1 - 4e-11 42.5 2.9 8.4e-11 41.5 2.9 1.6 1 0 0 1 1 1 1 PQ loop repeat Spore_YhaL PF14147.6 EAX88233.1 - 0.34 10.6 2.4 7.7 6.3 0.1 2.5 3 0 0 3 3 3 0 Sporulation protein YhaL DUF3646 PF12362.8 EAX88234.1 - 0.0023 18.2 0.2 0.0065 16.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III gamma and tau subunits C terminal MULE PF10551.9 EAX88235.1 - 1.6e-11 44.5 0.1 2.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX88235.1 - 0.06 13.8 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX88235.1 - 0.11 12.8 0.3 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 PWI domain DUF563 PF04577.14 EAX88236.1 - 2.8e-33 115.8 0.4 4.4e-33 115.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Trm56 PF01994.16 EAX88236.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 DUF3785 PF12653.7 EAX88237.1 - 0.06 13.5 3.7 0.078 13.1 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) Ank_2 PF12796.7 EAX88238.1 - 1.2e-44 150.8 7.8 1.9e-14 54.0 0.2 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88238.1 - 2.5e-25 88.5 0.1 1.8e-08 34.8 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX88238.1 - 4e-22 77.6 0.2 0.003 17.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX88238.1 - 1.6e-19 67.9 0.0 0.0057 17.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX88238.1 - 3.7e-17 62.1 2.8 8.1e-06 26.0 0.0 5.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) APG6_N PF17675.1 EAX88238.1 - 0.00037 21.0 6.7 0.00073 20.1 6.7 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF5071 PF16804.5 EAX88238.1 - 0.09 13.0 3.7 0.17 12.2 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Paralemmin PF03285.15 EAX88238.1 - 0.3 10.6 7.6 0.48 10.0 7.6 1.5 1 1 0 1 1 1 0 Paralemmin DUF4776 PF16003.5 EAX88238.1 - 1 8.3 5.6 1.5 7.8 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) LMBR1 PF04791.16 EAX88238.1 - 7.2 5.4 6.4 9.8 4.9 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Apolipoprotein PF01442.18 EAX88239.1 - 1.9e-11 44.2 34.7 0.00057 19.8 12.1 3.7 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EAX88239.1 - 2.8e-11 43.6 47.1 0.014 15.4 1.0 6.9 2 2 5 7 7 7 6 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 EAX88239.1 - 8.5e-06 25.7 37.7 0.0023 17.7 6.9 4.2 1 1 3 4 4 4 3 Family with sequence similarity 184, A and B DUF948 PF06103.11 EAX88239.1 - 1.2e-05 25.5 37.8 0.062 13.6 0.5 7.5 3 2 4 7 7 7 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EAX88239.1 - 7.9e-05 22.7 35.6 0.0035 17.4 1.6 6.2 1 1 6 7 7 7 3 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EAX88239.1 - 0.0004 19.8 33.4 0.004 16.6 1.8 4.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EAX88239.1 - 0.00051 20.5 31.1 0.064 13.8 4.1 6.1 2 2 4 6 6 6 3 Syntaxin 6, N-terminal EzrA PF06160.12 EAX88239.1 - 0.00077 17.8 26.7 0.0066 14.7 6.0 3.4 1 1 0 2 2 2 2 Septation ring formation regulator, EzrA V-SNARE_C PF12352.8 EAX88239.1 - 0.0012 19.1 0.1 0.0012 19.1 0.1 6.1 6 1 0 7 7 5 1 Snare region anchored in the vesicle membrane C-terminus LXG PF04740.12 EAX88239.1 - 0.0023 17.7 42.1 0.0051 16.6 1.6 5.8 3 2 2 6 6 5 2 LXG domain of WXG superfamily SHE3 PF17078.5 EAX88239.1 - 0.0042 16.8 2.6 0.0042 16.8 2.6 3.7 1 1 2 3 3 3 1 SWI5-dependent HO expression protein 3 DUF3584 PF12128.8 EAX88239.1 - 0.0048 14.5 38.2 0.012 13.2 10.5 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3584) Spc7 PF08317.11 EAX88239.1 - 0.0098 14.8 37.0 0.091 11.6 14.3 4.2 1 1 3 4 4 4 3 Spc7 kinetochore protein UPF0160 PF03690.13 EAX88239.1 - 0.0099 15.5 14.8 0.026 14.2 0.5 3.1 1 1 1 3 3 3 2 Uncharacterised protein family (UPF0160) APG17 PF04108.12 EAX88239.1 - 0.012 14.8 36.6 0.18 10.9 2.6 3.2 1 1 2 3 3 3 0 Autophagy protein Apg17 ApoLp-III PF07464.11 EAX88239.1 - 0.016 15.3 44.2 0.9 9.6 6.9 6.4 2 1 3 6 6 6 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 EAX88239.1 - 0.021 15.3 35.5 2 9.0 0.1 8.1 3 2 4 7 7 7 0 Nucleopolyhedrovirus P10 protein V-ATPase_G PF03179.15 EAX88239.1 - 0.023 15.2 2.1 0.023 15.2 2.1 4.9 3 2 2 5 5 4 0 Vacuolar (H+)-ATPase G subunit Exonuc_VII_L PF02601.15 EAX88239.1 - 0.026 14.1 39.0 0.21 11.1 11.4 4.0 1 1 2 3 3 2 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EAX88239.1 - 0.031 14.3 39.1 0.76 9.8 0.2 6.5 1 1 6 7 7 7 0 Laminin Domain II DUF603 PF04645.12 EAX88239.1 - 0.057 13.1 4.6 0.78 9.4 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function, DUF603 HalX PF08663.10 EAX88239.1 - 0.063 13.6 0.5 0.063 13.6 0.5 7.5 7 2 1 9 9 7 0 HalX domain Filament PF00038.21 EAX88239.1 - 0.24 11.0 35.5 2.1 7.8 13.2 4.0 2 1 1 4 4 4 0 Intermediate filament protein DUF641 PF04859.12 EAX88239.1 - 0.3 11.4 25.2 0.49 10.7 0.2 6.3 4 2 1 6 6 6 0 Plant protein of unknown function (DUF641) Muted PF14942.6 EAX88239.1 - 0.44 10.9 36.5 3 8.2 0.1 5.4 1 1 5 6 6 6 0 Organelle biogenesis, Muted-like protein DUF2935 PF11155.8 EAX88239.1 - 0.46 10.8 14.5 11 6.4 1.9 4.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Golgin_A5 PF09787.9 EAX88239.1 - 0.62 9.5 39.4 0.74 9.2 2.8 4.3 1 1 3 4 4 4 0 Golgin subfamily A member 5 TipAS PF07739.13 EAX88239.1 - 0.96 10.0 13.5 5.6 7.5 0.6 5.2 4 2 2 6 6 5 0 TipAS antibiotic-recognition domain Spectrin PF00435.21 EAX88239.1 - 1.1 9.8 29.0 4.5 7.8 4.9 6.1 3 2 3 6 6 6 0 Spectrin repeat XhlA PF10779.9 EAX88239.1 - 1.3 9.3 16.7 7.2 6.9 0.1 6.2 6 1 1 7 7 6 0 Haemolysin XhlA Nup54 PF13874.6 EAX88239.1 - 1.8 8.7 39.6 1.2 9.3 6.2 5.8 3 1 1 5 5 5 0 Nucleoporin complex subunit 54 Syntaxin PF00804.25 EAX88239.1 - 1.8 8.2 35.0 1 9.0 5.6 5.1 3 2 3 6 6 6 0 Syntaxin FUSC PF04632.12 EAX88239.1 - 1.8 7.0 20.0 0.59 8.6 0.5 3.1 1 1 1 3 3 3 0 Fusaric acid resistance protein family IFT57 PF10498.9 EAX88239.1 - 2.4 7.0 37.5 0.3 10.0 4.5 4.7 2 2 3 5 5 5 0 Intra-flagellar transport protein 57 Erp_C PF06780.11 EAX88239.1 - 2.4 8.1 4.9 32 4.5 0.0 4.3 3 2 1 5 5 4 0 Erp protein C-terminus Osmo_CC PF08946.10 EAX88239.1 - 2.7 8.3 10.3 3.9 7.8 0.1 4.8 4 1 1 5 5 4 0 Osmosensory transporter coiled coil DUF4164 PF13747.6 EAX88239.1 - 3.8 7.9 30.2 2.2 8.6 5.1 6.2 2 2 3 5 5 5 0 Domain of unknown function (DUF4164) Rootletin PF15035.6 EAX88239.1 - 4.1 7.4 37.1 42 4.1 24.2 4.2 1 1 1 2 2 1 0 Ciliary rootlet component, centrosome cohesion DUF148 PF02520.17 EAX88239.1 - 4.7 7.4 40.2 1.1 9.5 2.1 6.0 4 2 3 7 7 6 0 Domain of unknown function DUF148 Fib_alpha PF08702.10 EAX88239.1 - 5.8 7.1 43.4 2.3 8.4 2.8 6.2 2 2 4 6 6 6 0 Fibrinogen alpha/beta chain family AcylCoA_dehyd_C PF12186.8 EAX88239.1 - 6.8 6.9 12.0 5.2 7.2 0.0 5.2 4 2 2 6 6 5 0 Acyl-CoA dehydrogenase C terminal Tho2 PF11262.8 EAX88239.1 - 7.6 5.6 16.7 0.075 12.2 2.6 3.6 2 1 2 4 4 4 0 Transcription factor/nuclear export subunit protein 2 Tctex-1 PF03645.13 EAX88240.1 - 7.6e-20 71.1 0.1 7.6e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 EAX88240.1 - 0.0018 17.9 0.1 0.0019 17.9 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL4 family Pkinase PF00069.25 EAX88241.1 - 1.2e-42 146.2 0.0 1.4e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88241.1 - 6.3e-13 48.6 0.0 1.3e-12 47.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88241.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX88241.1 - 0.015 14.1 0.0 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EAX88241.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chal_sti_synt_N PF00195.19 EAX88242.1 - 0.031 13.7 2.7 0.06 12.8 2.7 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain SRI PF08236.11 EAX88242.1 - 0.15 12.3 5.0 0.32 11.2 5.0 1.7 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF3839 PF12943.7 EAX88243.1 - 1.5e-154 512.4 12.3 1.9e-154 512.1 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88243.1 - 0.097 13.1 1.5 0.47 10.9 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88243.1 - 0.34 11.4 5.5 4.5 7.8 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX88243.1 - 0.91 10.1 5.4 0.62 10.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) WD40 PF00400.32 EAX88246.1 - 0.23 12.4 2.0 14 6.7 0.1 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat SNARE PF05739.19 EAX88247.1 - 3.8e-09 36.4 0.4 1e-08 35.1 0.4 1.8 1 0 0 1 1 1 1 SNARE domain IKBKB_SDD PF18397.1 EAX88247.1 - 0.0021 17.4 0.5 0.0021 17.4 0.5 2.4 2 1 1 3 3 3 1 IQBAL scaffold dimerization domain Syntaxin_2 PF14523.6 EAX88247.1 - 0.013 15.8 7.9 0.013 15.8 7.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Rx_N PF18052.1 EAX88247.1 - 0.025 14.9 2.4 0.17 12.2 0.4 2.3 2 0 0 2 2 2 0 Rx N-terminal domain Syntaxin-6_N PF09177.11 EAX88247.1 - 0.031 14.8 4.8 0.078 13.5 0.7 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DASH_Dad1 PF08649.10 EAX88247.1 - 0.038 14.2 4.4 0.19 11.9 0.4 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad1 RPW8 PF05659.11 EAX88247.1 - 0.048 13.4 0.3 0.048 13.4 0.3 2.4 3 0 0 3 3 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5471 PF17565.2 EAX88247.1 - 0.05 13.9 0.5 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5471) Fzo_mitofusin PF04799.13 EAX88247.1 - 0.21 11.2 5.1 0.076 12.6 1.3 2.2 2 1 0 2 2 2 0 fzo-like conserved region Fez1 PF06818.15 EAX88247.1 - 0.36 11.3 9.1 0.16 12.4 1.8 2.2 1 1 1 2 2 2 0 Fez1 BEX PF04538.12 EAX88247.1 - 0.44 11.2 4.6 5.5 7.6 0.2 2.8 3 0 0 3 3 2 0 Brain expressed X-linked like family SKA2 PF16740.5 EAX88247.1 - 0.52 10.1 11.4 0.21 11.4 5.2 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Ada3 PF10198.9 EAX88247.1 - 0.6 10.2 8.2 0.28 11.3 4.6 1.9 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 Allexi_40kDa PF05549.11 EAX88247.1 - 0.94 8.9 8.5 0.14 11.7 1.4 2.2 1 1 2 3 3 3 0 Allexivirus 40kDa protein XhlA PF10779.9 EAX88247.1 - 1 9.6 10.8 3.7 7.8 0.8 2.9 2 1 0 2 2 2 0 Haemolysin XhlA FapA PF03961.13 EAX88247.1 - 1.2 7.7 10.8 0.29 9.7 5.9 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A LPP PF04728.13 EAX88247.1 - 2.1 8.8 9.4 2.3 8.7 4.9 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Tup_N PF08581.10 EAX88247.1 - 2.3 8.6 14.0 3.8 7.9 2.9 4.0 2 2 2 4 4 4 0 Tup N-terminal L31 PF09784.9 EAX88247.1 - 2.4 8.6 7.6 5.9 7.4 2.7 3.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 AAA_23 PF13476.6 EAX88247.1 - 2.7 8.5 11.5 0.14 12.6 3.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4795 PF16043.5 EAX88247.1 - 2.9 7.4 11.3 0.46 10.0 4.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DHR10 PF18595.1 EAX88247.1 - 5.8 7.0 9.4 13 5.9 0.4 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain NYD-SP28 PF14772.6 EAX88247.1 - 8.1 6.6 11.3 1.1 9.3 4.3 2.7 3 1 0 3 3 3 0 Sperm tail Imm25 PF15564.6 EAX88248.1 - 0.023 14.6 0.4 0.23 11.4 0.0 2.8 2 0 0 2 2 2 0 Immunity protein 25 DUF2155 PF09923.9 EAX88248.1 - 0.2 11.9 1.3 1.9 8.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2155) Meiosis_expr PF15163.6 EAX88249.1 - 0.055 14.2 1.5 0.065 13.9 0.6 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX88249.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family SOG2 PF10428.9 EAX88250.1 - 0.086 12.0 14.5 0.11 11.7 14.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein QWRF PF04484.12 EAX88250.1 - 3.1 7.4 13.4 7 6.3 12.5 1.9 2 0 0 2 2 2 0 QWRF family IF4E PF01652.18 EAX88253.1 - 1.7e-40 138.4 1.9 1.9e-40 138.2 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FNIP PF05725.12 EAX88254.1 - 0.05 13.8 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 FNIP Repeat DUF3447 PF11929.8 EAX88255.1 - 6.4e-39 131.8 8.1 6.4e-39 131.8 8.1 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88255.1 - 4.2e-20 72.1 1.3 1.6e-15 57.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88255.1 - 3.6e-19 68.3 0.0 1.5e-06 28.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX88255.1 - 1.8e-17 63.4 2.0 2e-05 25.0 0.0 5.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88255.1 - 5.5e-13 47.8 1.7 0.0032 17.9 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX88255.1 - 2.3e-09 37.3 0.8 8e-07 29.2 0.1 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Endonuc_subdom PF09062.10 EAX88255.1 - 0.14 13.0 5.0 0.35 11.7 4.3 2.1 1 1 1 2 2 2 0 PI-PfuI Endonuclease subdomain WD40 PF00400.32 EAX88256.1 - 9.5e-56 184.5 16.6 3.1e-07 31.0 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX88256.1 - 3.7e-14 52.8 0.8 0.0046 17.2 0.0 5.7 1 1 7 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAX88256.1 - 2e-09 36.7 10.7 0.024 13.3 0.1 6.0 1 1 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EAX88256.1 - 9.3e-09 35.4 2.7 1.3 8.8 0.0 4.4 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAX88256.1 - 1.1e-08 34.8 0.2 0.0018 17.6 0.0 4.3 3 1 3 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 EAX88256.1 - 1.7e-05 24.0 5.2 3.4 6.5 0.0 5.2 1 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3839 PF12943.7 EAX88259.1 - 4.2e-114 380.0 5.8 5e-114 379.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88259.1 - 0.21 12.1 1.5 0.89 10.0 1.0 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Herpes_IE2_3 PF03361.14 EAX88260.1 - 0.0045 16.9 1.0 0.29 11.0 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX88260.1 - 0.011 16.0 4.4 1.4 9.3 1.3 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region YlbD_coat PF14071.6 EAX88260.1 - 0.074 13.3 1.8 2.4 8.5 0.4 2.1 2 0 0 2 2 2 0 Putative coat protein MULE PF10551.9 EAX88261.1 - 4.7e-12 46.2 0.1 8.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain SIS PF01380.22 EAX88262.1 - 1.1e-36 125.6 0.5 4.8e-18 65.3 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EAX88262.1 - 6.4e-10 39.3 0.0 5.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAX88262.1 - 0.00029 19.9 0.1 0.00049 19.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.6 EAX88262.1 - 0.0017 18.2 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.21 EAX88262.1 - 0.074 11.7 0.3 3.9 6.1 0.2 2.3 1 1 0 2 2 2 0 Glutamine amidotransferases class-II Pyrophosphatase PF00719.19 EAX88263.1 - 1.5e-47 161.4 0.0 2.4e-47 160.7 0.0 1.3 2 0 0 2 2 2 1 Inorganic pyrophosphatase FlgN PF05130.12 EAX88264.1 - 0.04 14.4 0.0 0.088 13.3 0.0 1.5 2 0 0 2 2 2 0 FlgN protein CdvA PF18822.1 EAX88264.1 - 0.083 12.7 0.9 0.17 11.7 0.3 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Striatin PF08232.12 EAX88264.1 - 0.095 13.3 0.9 0.15 12.7 0.5 1.6 2 0 0 2 2 2 0 Striatin family Las1 PF04031.13 EAX88265.1 - 2.1e-28 99.4 0.1 6.9e-28 97.7 0.1 1.8 1 1 0 1 1 1 1 Las1-like MULE PF10551.9 EAX88266.1 - 1.4e-13 51.0 0.5 1.4e-13 51.0 0.5 2.6 3 0 0 3 3 3 1 MULE transposase domain WRKY PF03106.15 EAX88266.1 - 0.035 14.3 2.3 0.076 13.3 0.7 2.4 1 1 1 2 2 2 0 WRKY DNA -binding domain Transposase_mut PF00872.18 EAX88266.1 - 4.2 6.1 8.4 0.31 9.8 2.1 2.2 2 1 0 2 2 2 0 Transposase, Mutator family WD40_like PF17005.5 EAX88269.1 - 1.8e-05 24.2 3.4 0.0021 17.5 0.1 3.4 3 0 0 3 3 3 2 WD40-like domain zf-RRN7 PF11781.8 EAX88269.1 - 0.11 12.2 0.8 2.4 7.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tetraspanin PF00335.20 EAX88270.1 - 6.5e-05 22.8 16.8 0.0051 16.6 16.7 2.0 1 1 1 2 2 2 1 Tetraspanin family LMBR1 PF04791.16 EAX88270.1 - 0.0002 20.4 1.9 0.043 12.7 0.0 2.0 1 1 1 2 2 2 1 LMBR1-like membrane protein MFS_3 PF05977.13 EAX88270.1 - 0.0031 16.0 0.7 0.0032 15.9 0.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector COX4 PF02936.14 EAX88270.1 - 0.024 14.7 2.7 0.2 11.7 0.0 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV FtsX PF02687.21 EAX88270.1 - 0.025 15.0 2.0 0.025 15.0 2.0 2.5 1 1 1 2 2 2 0 FtsX-like permease family UPF0114 PF03350.16 EAX88270.1 - 0.031 14.5 0.0 0.031 14.5 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein family, UPF0114 FLILHELTA PF10306.9 EAX88270.1 - 0.091 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA CytochromB561_N PF09786.9 EAX88270.1 - 0.12 11.4 1.3 0.19 10.7 1.3 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF5527 PF17665.1 EAX88270.1 - 0.23 11.0 2.7 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5527) EI24 PF07264.11 EAX88270.1 - 0.38 11.0 9.3 1.5 9.1 9.4 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Trp_oprn_chp PF09534.10 EAX88270.1 - 0.4 10.5 2.6 1.3 8.8 2.7 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4191 PF13829.6 EAX88270.1 - 0.66 9.3 4.9 0.17 11.2 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1772 PF08592.11 EAX88270.1 - 1.9 8.8 5.0 1.4 9.2 1.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Glyco_hydro_47 PF01532.20 EAX88272.1 - 4.4e-26 91.8 4.4 9.1e-26 90.8 4.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4108 PF13390.6 EAX88274.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX88275.1 - 8.7e-81 272.3 3.7 1e-80 272.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ras PF00071.22 EAX88276.1 - 2.2e-30 105.4 0.0 3.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88276.1 - 5.5e-25 87.9 0.1 8.7e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88276.1 - 1.7e-09 37.4 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX88276.1 - 3.5e-08 33.2 1.1 7.2e-07 28.9 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX88276.1 - 5.9e-07 29.6 0.1 9.3e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX88276.1 - 2.5e-06 27.5 0.8 0.01 15.8 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX88276.1 - 3e-05 23.5 0.1 5.9e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX88276.1 - 5.4e-05 22.7 0.1 6.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX88276.1 - 0.002 17.9 0.3 0.011 15.4 0.3 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX88276.1 - 0.06 13.1 0.7 0.14 11.9 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAX88276.1 - 0.07 13.5 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EAX88276.1 - 0.079 12.1 0.1 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Pkinase PF00069.25 EAX88277.1 - 3.3e-72 243.0 0.0 4.1e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88277.1 - 1.3e-39 136.0 0.0 1.8e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88277.1 - 7.8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX88277.1 - 0.075 12.4 0.3 0.15 11.4 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX88277.1 - 0.082 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 EAX88277.1 - 0.12 13.1 6.6 0.56 10.9 6.6 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain PH PF00169.29 EAX88277.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 PH domain SlyX PF04102.12 EAX88278.1 - 0.014 16.0 2.0 0.014 16.0 2.0 3.5 1 1 1 3 3 3 0 SlyX SSFA2_C PF14723.6 EAX88278.1 - 0.07 13.0 4.5 0.18 11.7 4.4 1.8 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus SWI-SNF_Ssr4 PF08549.10 EAX88278.1 - 0.077 11.6 7.3 0.053 12.2 5.9 1.3 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Fib_alpha PF08702.10 EAX88278.1 - 0.085 13.0 18.9 0.72 10.0 2.1 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIVA PF05103.13 EAX88278.1 - 0.62 10.1 19.8 0.044 13.9 3.2 3.4 2 1 1 3 3 3 0 DivIVA protein Tup_N PF08581.10 EAX88278.1 - 1.2 9.5 11.6 0.23 11.8 4.4 3.2 3 1 1 4 4 4 0 Tup N-terminal DUF4407 PF14362.6 EAX88278.1 - 1.7 7.9 9.6 2.7 7.2 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sod_Ni PF09055.11 EAX88278.1 - 1.9 9.1 8.1 0.4 11.2 0.7 2.9 2 1 0 3 3 3 0 Nickel-containing superoxide dismutase DUF1664 PF07889.12 EAX88278.1 - 2.1 8.4 14.8 6.9 6.7 5.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4625 PF15418.6 EAX88279.1 - 0.033 14.4 1.2 0.098 12.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) DUF4469 PF14734.6 EAX88279.1 - 0.26 11.5 1.3 1.3 9.2 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold DUF3839 PF12943.7 EAX88280.1 - 6e-155 513.8 13.3 7.7e-155 513.4 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88280.1 - 0.042 14.3 1.5 0.2 12.1 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88280.1 - 0.55 10.7 7.6 2 8.9 1.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX88281.1 - 0.00029 21.3 0.2 0.00066 20.2 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX88281.1 - 0.013 15.0 0.7 0.16 11.5 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX88281.1 - 0.014 15.2 1.0 0.041 13.7 0.2 2.2 2 2 0 2 2 2 0 KilA-N domain DUF4483 PF14825.6 EAX88283.1 - 0.0051 16.6 6.7 0.4 10.4 1.3 3.0 2 1 0 3 3 3 2 Domain of unknown function (DUF4483) TMEM237 PF15383.6 EAX88284.1 - 3.8 6.5 14.3 0.037 13.1 4.2 2.4 1 1 1 2 2 2 0 Transmembrane protein 237 WD40 PF00400.32 EAX88285.1 - 8.5e-22 77.1 2.2 0.0054 17.6 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX88285.1 - 5.4e-09 36.2 0.0 0.63 10.4 0.0 6.4 3 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX88285.1 - 0.0028 16.7 0.0 4.5 6.1 0.0 3.8 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 EAX88285.1 - 0.006 16.2 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EAX88285.1 - 0.051 13.5 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EAX88285.1 - 0.053 13.4 0.0 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 EAX88286.1 - 9e-07 29.0 0.1 2.5e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.31 EAX88286.1 - 4.2e-05 23.7 0.0 9.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain CDC45 PF02724.14 EAX88286.1 - 0.022 13.1 2.8 0.028 12.7 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BRF1 PF07741.13 EAX88286.1 - 0.53 10.7 4.2 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Brf1-like TBP-binding domain HSP9_HSP12 PF04119.12 EAX88286.1 - 2.3 8.7 4.8 5.9 7.4 0.3 3.3 4 0 0 4 4 4 0 Heat shock protein 9/12 Phos_pyr_kin PF08543.12 EAX88287.1 - 7.3e-14 51.7 0.0 9.6e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EAX88287.1 - 2e-08 33.9 0.0 3.8e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Herpes_UL42 PF02282.16 EAX88287.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Glyco_hydro_17 PF00332.18 EAX88291.1 - 0.019 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Pkinase PF00069.25 EAX88292.1 - 2e-62 211.0 0.0 3.6e-62 210.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88292.1 - 4.2e-35 121.3 0.0 6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX88292.1 - 0.00019 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX88292.1 - 0.046 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase KKLCAg1 PF15204.6 EAX88292.1 - 1.1 9.3 3.6 2.8 8.1 2.4 2.2 1 1 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Ank_2 PF12796.7 EAX88293.1 - 1.4e-32 112.1 21.5 1e-15 58.1 2.9 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88293.1 - 9.9e-21 73.8 5.9 7.6e-08 32.8 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88293.1 - 1.6e-13 49.5 0.5 0.00054 20.2 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX88293.1 - 8.2e-12 45.1 4.3 0.00098 19.4 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX88293.1 - 4.5e-08 33.2 1.0 0.00034 20.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Staphylokinase PF02821.16 EAX88293.1 - 0.06 13.8 2.1 0.093 13.2 0.3 2.3 2 1 0 2 2 2 0 Staphylokinase/Streptokinase family Pox_A32 PF04665.12 EAX88294.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX88294.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4106 PF13388.6 EAX88295.1 - 4.1e-161 536.9 21.6 4.1e-161 536.9 21.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) ArsC PF03960.15 EAX88295.1 - 0.45 10.6 2.0 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 ArsC family Transp_Tc5_C PF04236.15 EAX88298.1 - 0.018 15.4 9.0 0.035 14.5 9.0 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-FPG_IleRS PF06827.14 EAX88298.1 - 0.021 14.7 0.5 0.021 14.7 0.5 3.4 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-C3HC4_3 PF13920.6 EAX88298.1 - 1.6 8.7 15.5 14 5.6 15.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYRC PF05965.14 EAX88299.1 - 3.4e-09 36.7 0.1 1.2e-07 31.8 0.0 3.1 3 0 0 3 3 3 1 F/Y rich C-terminus FYRN PF05964.14 EAX88299.1 - 5.4e-06 26.2 1.7 1.8e-05 24.5 0.1 2.8 3 0 0 3 3 3 1 F/Y-rich N-terminus Chromo PF00385.24 EAX88299.1 - 8.6e-06 25.6 0.7 0.017 15.0 0.3 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4106 PF13388.6 EAX88300.1 - 1.6e-250 831.4 18.6 1.6e-250 831.4 18.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX88300.1 - 0.0028 17.9 1.8 0.056 13.8 0.4 3.0 3 0 0 3 3 3 1 Kidney androgen-regulated TPR_MLP1_2 PF07926.12 EAX88301.1 - 0.0018 18.3 11.2 0.0018 18.3 11.2 11.4 6 3 4 11 11 11 4 TPR/MLP1/MLP2-like protein CLZ PF16526.5 EAX88301.1 - 0.026 14.9 1.1 0.026 14.9 1.1 11.4 7 4 5 13 13 13 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PriA_3primeBD PF17764.1 EAX88301.1 - 0.061 13.2 1.1 15 5.6 0.0 3.7 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) PSP PF04046.16 EAX88302.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX88303.1 - 0.073 13.5 1.3 0.1 13.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX88304.1 - 9e-30 102.5 11.7 9e-30 102.5 11.7 3.9 5 0 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX88304.1 - 0.034 13.9 0.2 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX88304.1 - 0.53 9.9 7.0 0.5 9.9 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) DUF240 PF03086.14 EAX88304.1 - 4.5 7.2 9.7 2.2 8.2 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF3839 PF12943.7 EAX88306.1 - 5.8e-141 468.0 11.7 7.2e-141 467.7 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88306.1 - 5 7.6 8.4 2.9 8.4 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX88307.1 - 1.8e-06 28.4 0.0 4.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX88307.1 - 0.01 15.7 1.6 0.057 13.3 0.7 2.5 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX88308.1 - 7.1e-35 119.3 0.6 1.4e-34 118.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF4108 PF13390.6 EAX88310.1 - 2.4e-56 189.6 4.0 2.7e-56 189.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4625 PF15418.6 EAX88311.1 - 4.9e-06 26.8 7.6 5.8 7.2 0.0 6.6 4 2 3 7 7 7 2 Domain of unknown function (DUF4625) DUF4832 PF16116.5 EAX88311.1 - 0.0015 18.4 2.9 0.16 11.8 0.1 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4832) Alph_Pro_TM PF09608.10 EAX88311.1 - 0.0072 16.2 0.0 7.9 6.2 0.0 4.3 5 2 1 6 6 6 1 Putative transmembrane protein (Alph_Pro_TM) Cag12 PF13117.6 EAX88311.1 - 0.05 14.1 2.7 0.16 12.5 0.1 3.3 3 2 1 4 4 4 0 Cag pathogenicity island protein Cag12 Guanylate_cyc PF00211.20 EAX88312.1 - 1.2e-20 73.9 1.0 2.1e-20 73.1 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX88312.1 - 3.4e-06 27.2 0.7 1.2e-05 25.5 0.3 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX88312.1 - 6.5e-05 22.9 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX88312.1 - 0.00016 21.9 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 EAX88312.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold SOBP PF15279.6 EAX88313.1 - 1.9 9.0 16.2 2.5 8.7 16.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Red1 PF07964.11 EAX88313.1 - 3.6 5.7 34.7 5.1 5.2 34.7 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Ndc1_Nup PF09531.10 EAX88313.1 - 9.4 4.8 12.6 12 4.4 12.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ras PF00071.22 EAX88314.1 - 4.3e-35 120.7 0.0 5.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88314.1 - 1e-27 96.8 0.0 1.8e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88314.1 - 3.4e-12 46.2 0.0 4.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX88314.1 - 7.3e-10 39.0 0.4 0.00056 19.9 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX88314.1 - 3.4e-08 33.3 0.0 9.1e-08 31.9 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX88314.1 - 3.3e-07 29.9 0.0 5.8e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88314.1 - 1.3e-06 28.5 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAX88314.1 - 0.00099 18.4 1.0 0.092 11.9 0.0 2.5 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 EAX88314.1 - 0.0035 17.2 1.1 0.075 12.8 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EAX88314.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EAX88314.1 - 0.026 15.1 0.0 0.036 14.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 EAX88314.1 - 0.043 13.8 0.0 0.07 13.2 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_helicase PF00910.22 EAX88314.1 - 0.082 13.3 0.3 0.2 12.1 0.1 1.8 2 1 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 EAX88314.1 - 0.089 12.5 0.1 0.64 9.8 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX88314.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Hpr_kinase_C PF07475.12 EAX88314.1 - 0.16 11.4 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Ribul_P_3_epim PF00834.19 EAX88315.1 - 1.1e-76 256.7 0.4 1.3e-76 256.4 0.4 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 EAX88315.1 - 0.0069 16.0 1.2 0.49 10.0 1.2 2.3 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 EAX88315.1 - 0.007 16.2 0.1 0.032 14.0 0.0 2.0 1 1 2 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain DDR PF08841.10 EAX88316.1 - 0.058 12.4 0.2 0.059 12.3 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain RTP1_C1 PF10363.9 EAX88317.1 - 0.0059 16.8 2.3 3.2 8.0 0.0 4.7 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 DAGK_prokar PF01219.19 EAX88317.1 - 0.017 14.9 0.1 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Vac14_Fab1_bd PF12755.7 EAX88317.1 - 0.02 15.4 6.4 0.16 12.6 0.1 4.5 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EAX88317.1 - 0.033 14.4 1.3 57 4.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF3839 PF12943.7 EAX88318.1 - 1.9e-156 518.7 15.3 2.4e-156 518.4 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX88318.1 - 0.0096 16.2 1.6 0.55 10.6 0.1 3.3 3 1 0 3 3 3 1 Rx N-terminal domain Fez1 PF06818.15 EAX88318.1 - 0.17 12.3 2.1 0.27 11.7 0.5 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88318.1 - 0.29 11.6 5.6 2.1 8.9 0.2 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX88318.1 - 0.29 11.0 2.0 0.66 9.8 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase F5_F8_type_C PF00754.25 EAX88321.1 - 2.8e-05 24.2 0.0 8.2e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX88322.1 - 3.1e-06 27.3 0.0 2.7e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain DUF2939 PF11159.8 EAX88323.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX88323.1 - 1.9 7.4 3.3 1.9 7.5 3.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX88323.1 - 2.9 7.9 6.9 3 7.8 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX88324.1 - 0.026 14.5 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Sugar_tr PF00083.24 EAX88325.1 - 7.1e-50 170.2 42.4 3.7e-47 161.2 42.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX88325.1 - 1.2e-16 60.6 33.2 1.2e-16 60.6 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EAX88326.1 - 6.9e-63 212.5 0.0 7.6e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88326.1 - 7.1e-39 133.6 0.0 8e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX88326.1 - 4.5e-05 23.5 0.4 0.00056 19.9 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX88326.1 - 0.00048 19.2 0.5 0.0006 18.9 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EAX88326.1 - 0.0085 15.7 0.5 0.011 15.3 0.5 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EAX88326.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EAX88326.1 - 0.059 13.0 0.0 2.2 7.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX88326.1 - 0.059 12.7 2.3 0.13 11.6 2.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPIP PF06409.11 EAX88326.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Pkinase PF00069.25 EAX88327.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain PSP PF04046.16 EAX88328.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88329.1 - 0.055 14.0 5.5 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX88329.1 - 4.7 7.2 8.0 5.2 7.1 8.0 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX88332.1 - 2.4e-157 521.6 12.6 3.1e-157 521.3 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88332.1 - 0.026 15.0 1.6 0.075 13.5 0.4 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88332.1 - 0.044 14.2 3.7 2.2 8.8 0.1 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase P4Ha_N PF08336.11 EAX88332.1 - 0.27 11.2 3.5 9.1 6.3 0.0 2.8 2 2 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2408 PF10303.9 EAX88332.1 - 1.6 9.3 4.8 0.7 10.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Terminase_2 PF03592.16 EAX88332.1 - 1.9 9.0 6.1 2.3 8.7 1.6 2.7 1 1 1 2 2 2 0 Terminase small subunit DUF1899 PF08953.11 EAX88333.1 - 8.1e-21 73.7 0.4 7.1e-20 70.7 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EAX88333.1 - 3.9e-10 39.5 0.0 6.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EAX88333.1 - 9.6e-09 35.7 0.2 0.00053 20.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAX88333.1 - 1.5e-05 24.1 0.0 0.00041 19.4 0.0 2.6 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EAX88333.1 - 0.00012 22.3 1.0 0.095 13.0 0.3 2.9 2 1 1 3 3 2 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 EAX88333.1 - 0.0092 16.1 3.2 0.017 15.2 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAX88333.1 - 0.01 15.9 5.7 0.024 14.7 5.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Mt_ATP-synt_D PF05873.12 EAX88333.1 - 0.057 13.3 0.5 0.15 11.9 0.5 1.7 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Cnn_1N PF07989.11 EAX88333.1 - 0.064 13.4 2.0 0.13 12.4 2.0 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EAX88333.1 - 0.08 12.7 5.8 0.27 11.0 5.2 2.2 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 EAX88333.1 - 0.12 12.7 2.1 0.27 11.5 2.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper WD40_alt PF14077.6 EAX88333.1 - 0.15 11.9 2.7 0.28 11.1 2.7 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Prefoldin PF02996.17 EAX88333.1 - 0.29 11.1 3.4 0.14 12.1 1.1 1.6 2 0 0 2 2 1 0 Prefoldin subunit IFP_35_N PF07334.13 EAX88333.1 - 0.29 11.2 3.3 0.76 9.9 3.3 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ZapB PF06005.12 EAX88333.1 - 0.48 10.9 6.1 1.1 9.8 6.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 EAX88333.1 - 0.56 10.6 5.1 1.1 9.6 5.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family APG6_N PF17675.1 EAX88333.1 - 1.1 9.8 6.5 1.9 9.0 6.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EAX88333.1 - 1.2 9.6 4.2 1.9 9.0 1.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Chorein_N PF12624.7 EAX88334.1 - 7.1e-20 71.3 1.1 3.5e-19 69.0 0.2 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 PKD_2 PF16407.5 EAX88334.1 - 0.29 11.3 2.0 0.68 10.1 0.5 2.4 2 0 0 2 2 2 0 PKD-like family DUF1664 PF07889.12 EAX88336.1 - 3.5e-05 23.8 58.6 0.14 12.2 4.4 6.7 1 1 8 9 9 9 7 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EAX88336.1 - 0.00021 21.3 67.9 0.066 13.2 12.7 5.3 1 1 4 6 6 6 4 Laminin Domain II TPR_MLP1_2 PF07926.12 EAX88336.1 - 0.00026 21.0 65.7 0.017 15.2 11.2 5.5 2 2 3 5 5 5 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 EAX88336.1 - 0.00037 19.3 26.1 0.00037 19.3 26.1 3.1 1 1 3 4 4 4 3 AAA domain Nsp1_C PF05064.13 EAX88336.1 - 0.002 17.9 7.9 0.002 17.9 7.9 5.5 1 1 3 5 5 4 1 Nsp1-like C-terminal region MscS_porin PF12795.7 EAX88336.1 - 0.0023 17.5 4.6 0.0023 17.5 4.6 4.8 1 1 4 5 5 5 1 Mechanosensitive ion channel porin domain LPP PF04728.13 EAX88336.1 - 0.0073 16.7 2.2 0.0073 16.7 2.2 8.4 6 2 3 10 10 8 1 Lipoprotein leucine-zipper APG6_N PF17675.1 EAX88336.1 - 0.013 16.0 66.2 1.6 9.3 10.3 5.3 1 1 4 5 5 5 0 Apg6 coiled-coil region Spc7 PF08317.11 EAX88336.1 - 0.044 12.7 73.9 0.64 8.8 22.0 4.5 1 1 2 4 4 4 0 Spc7 kinetochore protein Sec2p PF06428.11 EAX88336.1 - 0.047 13.7 0.5 0.047 13.7 0.5 6.6 3 2 1 5 5 5 0 GDP/GTP exchange factor Sec2p DHR10 PF18595.1 EAX88336.1 - 0.051 13.6 58.7 0.052 13.6 0.8 6.1 3 2 1 5 5 5 0 Designed helical repeat protein 10 domain DotD PF16816.5 EAX88336.1 - 0.079 12.9 3.8 0.2 11.6 0.8 3.0 2 1 0 2 2 2 0 DotD protein DUF948 PF06103.11 EAX88336.1 - 0.18 12.1 44.8 0.09 13.0 6.6 6.4 2 1 3 5 5 4 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 EAX88336.1 - 0.27 10.8 65.7 10 5.6 15.8 4.7 1 1 2 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 EAX88336.1 - 0.39 10.9 59.6 0.82 9.9 13.9 4.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 EAX88336.1 - 0.86 7.7 61.8 0.78 7.8 34.3 3.2 1 1 2 3 3 3 0 HOOK protein Golgin_A5 PF09787.9 EAX88336.1 - 0.89 9.0 73.0 0.34 10.3 14.5 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EAX88336.1 - 1.3 8.3 45.7 0.28 10.5 6.4 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 EAX88336.1 - 1.6 8.4 65.3 6 6.5 22.2 4.5 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Spectrin PF00435.21 EAX88336.1 - 1.8 9.1 49.1 0.08 13.4 2.1 5.5 2 1 2 5 5 5 0 Spectrin repeat Tektin PF03148.14 EAX88336.1 - 2.3 6.9 69.1 0.014 14.2 36.6 3.7 1 1 2 3 3 3 0 Tektin family Med9 PF07544.13 EAX88336.1 - 2.6 8.2 56.8 0.54 10.4 4.2 7.4 2 1 3 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 EAX88336.1 - 2.8 7.7 71.9 0.35 10.7 18.7 4.6 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH ALIX_LYPXL_bnd PF13949.6 EAX88336.1 - 3.5 6.8 63.6 46 3.2 34.4 3.0 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV YcgR PF07317.12 EAX88336.1 - 5.2 7.0 11.8 6.5 6.7 1.3 3.6 3 1 0 3 3 3 0 Flagellar regulator YcgR Fez1 PF06818.15 EAX88336.1 - 6.5 7.2 60.7 3.4 8.1 15.1 4.3 1 1 3 4 4 4 0 Fez1 DUF3584 PF12128.8 EAX88336.1 - 7.7 3.9 60.5 42 1.4 27.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FPP PF05911.11 EAX88336.1 - 9.7 4.2 78.5 0.058 11.6 32.3 3.1 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil GPS2_interact PF15784.5 EAX88338.1 - 0.029 14.8 0.5 0.036 14.5 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX88339.1 - 0.12 12.3 9.1 0.14 12.1 9.1 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88339.1 - 0.81 10.1 5.5 0.93 9.9 5.5 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX88340.1 - 2.4e-77 259.7 10.0 2.7e-77 259.5 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX88340.1 - 0.014 15.5 0.1 4.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FKBP_N PF01346.18 EAX88340.1 - 0.096 13.7 0.5 0.19 12.7 0.4 1.5 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NTP_transf_6 PF06042.11 EAX88340.1 - 0.12 12.2 0.9 0.7 9.7 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase APC_u14 PF16635.5 EAX88340.1 - 0.15 12.6 2.6 0.27 11.8 2.6 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr DUF3839 PF12943.7 EAX88341.1 - 2.3e-40 138.6 1.6 2.8e-40 138.3 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX88341.1 - 0.11 12.8 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3447 PF11929.8 EAX88342.1 - 3e-41 139.2 4.4 3e-41 139.2 4.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88342.1 - 0.00066 20.2 0.1 0.0021 18.6 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF5119 PF17145.4 EAX88342.1 - 0.06 13.3 1.1 0.1 12.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) Ank_4 PF13637.6 EAX88342.1 - 0.11 13.1 0.2 26 5.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88343.1 - 1.7e-46 156.0 5.1 4.7e-14 52.5 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88343.1 - 1.1e-40 136.4 2.3 2.5e-07 30.8 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 EAX88343.1 - 2.1e-37 127.6 7.7 3.5e-15 56.3 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88343.1 - 3.5e-32 106.8 5.9 3.8e-05 23.7 0.0 6.6 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX88343.1 - 9.7e-28 95.9 5.7 1.2e-09 38.2 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Arg_repressor PF01316.21 EAX88343.1 - 0.023 14.4 0.4 47 3.8 0.0 3.8 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Beach PF02138.18 EAX88344.1 - 3.5e-25 88.9 0.3 7.7e-23 81.2 0.3 2.5 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX88344.1 - 1.7e-08 34.1 3.6 2.1e-08 33.8 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) DUF4107 PF13389.6 EAX88346.1 - 4.4e-73 244.8 4.6 5.2e-73 244.5 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX88346.1 - 0.02 15.3 0.2 0.047 14.1 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX88346.1 - 0.14 10.6 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX88347.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX88347.1 - 0.2 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DNA_pol_B_2 PF03175.13 EAX88348.1 - 1e-08 34.5 1.6 2e-08 33.6 1.6 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX88348.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX88348.1 - 0.15 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAX88350.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX88352.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX88352.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX88352.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX88352.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX88352.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX88352.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX88352.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX88352.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX88352.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX88352.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX88352.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX88352.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX88353.1 - 1.5e-34 118.2 0.8 2.8e-34 117.3 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX88353.1 - 0.1 13.3 1.4 18 6.1 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 T5orf172 PF10544.9 EAX88354.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX88354.1 - 0.0048 16.7 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX88355.1 - 2.1e-138 459.6 15.1 2.6e-138 459.3 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88355.1 - 1.1 9.8 5.6 2.7 8.5 0.1 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MatE PF01554.18 EAX88356.1 - 1.1e-24 87.0 30.3 9.5e-14 51.4 8.6 2.8 2 1 1 3 3 3 2 MatE Guanylate_cyc PF00211.20 EAX88358.1 - 1.8e-40 138.5 0.1 3.2e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX88358.1 - 6.6e-07 29.5 0.6 1.8e-06 28.2 0.6 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 EAX88358.1 - 5.3e-05 22.8 2.1 0.012 15.0 0.2 2.2 1 1 1 2 2 2 2 Heme NO binding associated PAS_8 PF13188.7 EAX88358.1 - 0.0001 22.2 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX88358.1 - 0.0037 17.2 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold Sld7_C PF18596.1 EAX88358.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Sld7 C-terminal domain PAS_4 PF08448.10 EAX88358.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Ank_2 PF12796.7 EAX88359.1 - 1.7e-27 95.8 2.3 2.1e-11 44.2 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88359.1 - 6.8e-23 80.7 0.4 2.6e-07 31.0 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88359.1 - 5.3e-21 74.4 1.2 1.4e-07 31.6 0.0 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88359.1 - 4.1e-18 63.6 0.5 0.0058 17.0 0.1 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EAX88359.1 - 1.6e-15 56.8 1.4 0.014 15.8 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 EAX88359.1 - 5.7e-06 26.2 12.5 4.6e-05 23.3 0.4 3.9 1 1 2 4 4 4 2 Domain of unknown function (DUF3447) RE_TdeIII PF09520.10 EAX88359.1 - 0.02 14.6 0.3 0.075 12.7 0.1 2.0 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII DUF1515 PF07439.11 EAX88360.1 - 3.4 7.7 20.8 10 6.2 0.5 5.6 4 2 1 5 5 5 0 Protein of unknown function (DUF1515) Ras PF00071.22 EAX88361.1 - 2.5e-52 176.8 1.0 2.9e-52 176.5 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88361.1 - 3.9e-31 107.8 0.4 6.5e-31 107.1 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88361.1 - 9.8e-17 60.9 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX88361.1 - 2.5e-08 33.6 0.5 3e-08 33.3 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88361.1 - 5.2e-07 29.7 0.0 7.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX88361.1 - 1.5e-05 24.6 0.3 6.8e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX88361.1 - 3e-05 24.0 0.3 0.028 14.3 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EAX88361.1 - 0.0003 20.4 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EAX88361.1 - 0.0078 16.0 0.1 0.027 14.3 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EAX88361.1 - 0.021 14.6 0.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EAX88361.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EAX88361.1 - 0.058 12.8 0.1 0.083 12.3 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EAX88361.1 - 0.061 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 EAX88361.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 EAX88361.1 - 0.071 12.2 2.6 10 5.2 0.7 2.9 1 1 1 2 2 2 0 G-protein alpha subunit DUF3781 PF12636.7 EAX88362.1 - 0.083 12.8 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX88363.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX88365.1 - 5.3e-10 39.6 0.1 1.3e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX88365.1 - 0.0096 14.8 0.2 0.021 13.7 0.2 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX88365.1 - 0.013 15.3 0.2 0.069 12.9 0.1 1.9 1 1 1 2 2 2 0 Transposase FAR1 PF03101.15 EAX88365.1 - 0.1 13.3 0.1 0.23 12.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF1548 PF07579.11 EAX88366.1 - 0.0077 16.6 0.7 0.015 15.6 0.6 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1548) Osmo_CC PF08946.10 EAX88366.1 - 0.63 10.3 3.0 2.9 8.2 1.1 2.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Mistic PF11458.8 EAX88367.1 - 8.1 6.5 8.6 0.77 9.8 0.0 3.6 4 1 1 5 5 5 0 Membrane-integrating protein Mistic PRA-PH PF01503.17 EAX88368.1 - 0.76 10.3 4.0 10 6.6 3.5 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4107 PF13389.6 EAX88370.1 - 1.1e-70 237.0 3.4 1.5e-70 236.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX88371.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX88373.1 - 8.8e-12 44.9 0.3 1e-11 44.6 0.3 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3038 PF11237.8 EAX88373.1 - 0.12 12.4 0.2 0.15 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF3839 PF12943.7 EAX88374.1 - 3.5e-156 517.8 13.2 4.5e-156 517.4 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88374.1 - 3.2 8.3 7.0 2.6 8.5 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAS_N PF17828.1 EAX88375.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX88376.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88376.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX88377.1 - 0.1 11.5 0.1 0.098 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX88378.1 - 0.028 14.3 1.0 0.055 13.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX88380.1 - 9.1e-158 523.0 13.2 1.1e-157 522.7 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX88380.1 - 0.19 11.6 1.2 0.66 9.8 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX88380.1 - 2.3 8.7 6.2 2.5 8.6 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX88381.1 - 3e-40 136.6 0.7 5.7e-40 135.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX88381.1 - 0.011 16.3 0.0 0.034 14.8 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Trypan_PARP PF05887.11 EAX88384.1 - 0.025 14.5 9.7 0.036 14.1 9.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX88385.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX88386.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX88386.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX88387.1 - 0.074 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX88387.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX88389.1 - 2.7e-42 143.1 0.7 6.2e-42 142.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain GAGA_bind PF06217.12 EAX88390.1 - 0.067 13.5 5.4 0.083 13.2 5.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PcfK PF14058.6 EAX88390.1 - 3.3 8.0 16.9 4.7 7.5 16.9 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX88390.1 - 5.4 7.0 7.8 12 5.8 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX88391.1 - 3.2e-63 211.9 5.9 3.6e-63 211.8 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX88393.1 - 1.6e-261 867.7 18.8 1.6e-261 867.7 18.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX88393.1 - 0.11 12.8 2.6 1.4 9.3 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated Myb_DNA-binding PF00249.31 EAX88394.1 - 3.3e-07 30.4 0.1 9.1e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88394.1 - 1.7e-05 24.9 2.0 2.5e-05 24.4 0.5 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain DivIC PF04977.15 EAX88394.1 - 1.3 8.8 4.2 2.5 7.9 0.1 2.9 2 1 1 3 3 3 0 Septum formation initiator COPIIcoated_ERV PF07970.12 EAX88395.1 - 2.2e-16 60.4 0.1 3.5e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX88395.1 - 1.2e-10 41.5 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ADSL_C PF10397.9 EAX88396.1 - 0.037 14.6 0.3 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Fzo_mitofusin PF04799.13 EAX88396.1 - 5.1 6.6 9.8 0.31 10.6 3.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region L27_1 PF09058.10 EAX88397.1 - 0.01 15.8 3.3 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 L27_1 CREPT PF16566.5 EAX88397.1 - 0.041 14.1 0.7 0.11 12.7 0.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX88397.1 - 0.091 12.8 0.8 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX88397.1 - 0.91 9.7 7.4 0.47 10.6 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PriX PF18689.1 EAX88397.1 - 3.9 7.9 7.0 2.8 8.3 0.3 3.0 3 1 0 3 3 3 0 Primase X DUF3839 PF12943.7 EAX88398.1 - 1.5e-157 522.3 14.1 1.7e-157 522.1 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX88398.1 - 0.13 12.5 0.9 2.4 8.5 0.0 2.9 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX88398.1 - 0.16 11.8 1.5 0.5 10.2 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX88398.1 - 0.43 11.1 7.1 1.9 9.0 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX88400.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88401.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP BNR_6 PF15899.5 EAX88402.1 - 0.083 13.0 6.3 8.2 6.8 0.0 5.0 4 0 0 4 4 4 0 BNR-Asp box repeat DNA_pol_B PF00136.21 EAX88403.1 - 3.4e-26 92.0 4.3 6.9e-16 58.0 0.3 2.2 2 0 0 2 2 2 2 DNA polymerase family B IBR PF01485.21 EAX88405.1 - 0.078 13.2 37.6 0.039 14.2 9.5 4.1 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain TipAS PF07739.13 EAX88406.1 - 0.082 13.5 4.9 14 6.2 0.0 4.4 4 1 0 4 4 4 0 TipAS antibiotic-recognition domain ZnuA PF01297.17 EAX88406.1 - 0.083 12.3 0.7 0.31 10.4 0.7 1.9 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF3839 PF12943.7 EAX88407.1 - 3.6e-148 491.6 12.4 4.2e-148 491.3 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Germane PF10646.9 EAX88407.1 - 0.016 16.0 0.3 0.028 15.2 0.3 1.3 1 0 0 1 1 1 0 Sporulation and spore germination NTP_transf_6 PF06042.11 EAX88407.1 - 0.073 12.9 1.4 0.31 10.9 0.7 2.2 2 1 1 3 3 3 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX88409.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88410.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Sec1 PF00995.23 EAX88411.1 - 4.4e-87 293.7 0.7 5.1e-87 293.5 0.7 1.0 1 0 0 1 1 1 1 Sec1 family CbiA PF01656.23 EAX88411.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fib_alpha PF08702.10 EAX88411.1 - 0.41 10.8 2.1 3 8.0 0.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Gly_rich PF12810.7 EAX88412.1 - 1.5e-58 198.6 36.7 1.7e-58 198.4 36.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX88413.1 - 2.1e-55 188.3 33.3 2.4e-55 188.1 33.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX88414.1 - 4e-56 190.7 38.0 4.8e-56 190.4 38.0 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAX88415.1 - 1.3e-35 121.2 7.3 1.3e-35 121.2 7.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88415.1 - 0.0055 17.3 0.1 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Porin_3 PF01459.22 EAX88416.1 - 0.0042 16.6 0.4 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic porin DUF3447 PF11929.8 EAX88417.1 - 4.4e-37 125.9 8.2 4.4e-37 125.9 8.2 4.4 3 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88417.1 - 1.3e-34 118.6 23.2 2.2e-14 53.8 1.4 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88417.1 - 5.4e-33 112.9 5.4 3.1e-09 37.2 0.0 7.4 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX88417.1 - 8.2e-29 98.8 1.5 7.1e-06 26.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX88417.1 - 1.3e-23 80.5 6.7 0.00054 20.2 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX88417.1 - 5.2e-21 74.4 1.3 5.9e-08 32.8 0.0 5.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) ATP13 PF12921.7 EAX88417.1 - 2.9 7.8 11.7 0.16 11.8 1.1 3.5 3 2 1 4 4 4 0 Mitochondrial ATPase expression DUF724 PF05266.14 EAX88419.1 - 0.048 13.5 0.4 0.063 13.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Ldh_1_N PF00056.23 EAX88420.1 - 1.1e-28 100.1 0.0 1.9e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX88420.1 - 1.2e-24 87.1 0.0 2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DUF3447 PF11929.8 EAX88421.1 - 2.1e-08 34.0 1.8 6.9e-07 29.1 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88421.1 - 0.0038 17.8 0.1 0.78 10.4 0.0 3.0 1 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88421.1 - 0.061 13.9 0.0 0.33 11.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88422.1 - 1.1e-10 42.0 0.9 4.2e-08 33.7 0.0 3.8 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88422.1 - 1.6e-07 31.4 0.1 0.00069 19.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX88422.1 - 3.8e-07 30.3 0.2 0.00034 20.9 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX88422.1 - 1e-06 29.2 2.6 0.0086 16.6 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88422.1 - 2.6e-05 24.2 0.8 0.068 13.8 0.0 5.1 7 0 0 7 7 7 1 Ankyrin repeat Glyco_hydro_115 PF15979.5 EAX88422.1 - 0.091 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 Myb_DNA-binding PF00249.31 EAX88423.1 - 8.8e-18 64.2 0.4 2.9e-14 53.0 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88423.1 - 1.5e-13 50.8 3.9 1.6e-09 37.9 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX88423.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Myb DNA-binding like SLIDE PF09111.10 EAX88423.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.6 1 1 0 1 1 1 0 SLIDE Pox_A32 PF04665.12 EAX88425.1 - 8e-08 32.0 0.4 1.6e-07 31.0 0.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX88425.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX88425.1 - 0.03 14.2 1.6 0.044 13.7 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 HEPN_AbiA_CTD PF18732.1 EAX88425.1 - 0.075 13.0 2.2 0.14 12.1 2.2 1.4 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain BspA_v PF18220.1 EAX88426.1 - 0.88 9.7 6.3 3.2 7.9 1.1 2.3 2 0 0 2 2 2 0 Adhesin BspA variable domain FAS_N PF17828.1 EAX88428.1 - 0.0033 17.4 0.2 0.0052 16.8 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DinB PF05163.12 EAX88428.1 - 0.093 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 DinB family Peptidase_C14 PF00656.22 EAX88428.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Fe-ADH PF00465.19 EAX88430.1 - 2.4e-05 23.4 0.0 2.4e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase BppL_N PF18338.1 EAX88430.1 - 0.028 14.2 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain Peptidase_M26_N PF05342.14 EAX88431.1 - 0.0091 15.4 0.6 0.017 14.5 0.6 1.3 1 0 0 1 1 1 1 M26 IgA1-specific Metallo-endopeptidase N-terminal region TPR_12 PF13424.6 EAX88431.1 - 0.011 16.0 0.0 0.45 10.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAX88431.1 - 0.017 14.9 0.0 7.4 6.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAX88431.1 - 0.078 12.4 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR Y1_Tnp PF01797.16 EAX88432.1 - 0.028 14.5 2.1 5.6 7.1 0.5 2.5 2 0 0 2 2 2 0 Transposase IS200 like RICTOR_N PF14664.6 EAX88433.1 - 0.0045 16.0 0.3 0.0064 15.5 0.3 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Ank PF00023.30 EAX88435.1 - 5.6e-103 333.3 19.1 2.3e-09 37.2 0.0 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.7 EAX88435.1 - 1.6e-102 336.2 44.6 5.1e-16 59.0 1.3 8.6 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88435.1 - 4.4e-86 282.2 19.1 2.8e-12 46.9 0.0 13.3 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88435.1 - 5.7e-75 238.3 24.3 6.6e-06 26.1 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 EAX88435.1 - 2.1e-71 235.1 8.3 3.4e-12 46.4 0.1 8.9 5 2 2 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88435.1 - 1.9e-38 130.3 5.4 1.9e-38 130.3 5.4 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX88435.1 - 1.3e-10 41.3 0.0 0.11 12.7 0.0 5.9 1 1 4 6 6 6 6 N terminal of Calcineurin-like phosphoesterase ThiS-like PF14453.6 EAX88435.1 - 1.7e-06 28.0 17.7 7.4 6.7 0.1 10.6 4 3 8 12 12 12 2 ThiS-like ubiquitin PH_8 PF15409.6 EAX88435.1 - 4.3e-06 26.9 3.3 4.5 7.6 0.0 7.3 2 1 5 8 8 8 1 Pleckstrin homology domain CEP44 PF15007.6 EAX88435.1 - 7.2e-06 26.2 0.0 28 4.9 0.0 7.1 2 2 8 10 10 10 0 Centrosomal spindle body, CEP44 Ribosomal_S6 PF01250.17 EAX88435.1 - 0.0038 17.5 1.8 64 3.9 0.0 6.1 2 2 3 7 7 7 0 Ribosomal protein S6 NMT1_2 PF13379.6 EAX88435.1 - 0.0078 15.9 0.1 14 5.2 0.0 3.8 1 1 3 4 4 4 0 NMT1-like family CCG PF02754.16 EAX88435.1 - 0.046 13.9 0.2 14 6.0 0.0 3.5 3 0 0 3 3 3 0 Cysteine-rich domain Myb_DNA-bind_6 PF13921.6 EAX88435.1 - 0.11 12.8 0.7 36 4.7 0.0 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Ntox27 PF15531.6 EAX88435.1 - 1.7 8.5 5.9 53 3.7 0.1 4.2 1 1 3 5 5 5 0 Bacterial toxin 27 SNARE PF05739.19 EAX88436.1 - 0.00035 20.5 0.1 0.00082 19.3 0.1 1.6 1 0 0 1 1 1 1 SNARE domain MitMem_reg PF13012.6 EAX88436.1 - 0.017 15.5 0.1 0.18 12.2 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function UPF0242 PF06785.11 EAX88436.1 - 0.021 14.9 0.3 0.037 14.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 EAX88436.1 - 0.066 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RmuC PF02646.16 EAX88436.1 - 0.077 12.1 1.1 0.13 11.4 1.1 1.3 1 0 0 1 1 1 0 RmuC family Ank PF00023.30 EAX88437.1 - 4.4e-62 204.0 4.5 1.9e-09 37.5 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.7 EAX88437.1 - 1e-52 176.6 10.1 3.6e-15 56.3 0.4 5.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88437.1 - 5.1e-50 166.9 5.8 1.7e-12 47.3 0.0 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88437.1 - 9.6e-49 163.2 5.7 1.4e-11 44.6 0.0 9.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88437.1 - 1e-43 142.3 10.4 6e-06 26.2 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX88437.1 - 4.9e-39 132.1 5.3 4.9e-39 132.1 5.3 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) ThiS-like PF14453.6 EAX88437.1 - 1.2e-06 28.5 6.5 16 5.7 0.0 6.9 4 2 3 7 7 7 2 ThiS-like ubiquitin CEP44 PF15007.6 EAX88437.1 - 0.0037 17.4 0.0 43 4.3 0.0 4.5 1 1 4 5 5 5 0 Centrosomal spindle body, CEP44 PH_8 PF15409.6 EAX88437.1 - 0.018 15.3 0.3 1.1e+02 3.2 0.0 4.8 2 1 3 5 5 5 0 Pleckstrin homology domain DUF4512 PF14975.6 EAX88437.1 - 0.15 12.9 0.2 19 6.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4512) NMT1_2 PF13379.6 EAX88437.1 - 0.16 11.6 0.0 5 6.7 0.0 2.7 1 1 2 3 3 3 0 NMT1-like family Ank_2 PF12796.7 EAX88438.1 - 4.6e-95 312.3 26.9 7.4e-22 77.7 1.2 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88438.1 - 8.3e-91 294.8 6.7 7.9e-11 41.9 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX88438.1 - 1.2e-84 277.2 9.4 1.4e-14 54.0 0.1 6.0 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88438.1 - 3.1e-70 231.7 7.7 2.4e-11 43.9 0.0 8.0 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88438.1 - 1.6e-65 209.3 11.6 1.1e-06 28.5 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat MetallophosN PF16371.5 EAX88438.1 - 8.1e-13 48.5 0.0 0.011 16.0 0.0 5.5 1 1 4 5 5 5 4 N terminal of Calcineurin-like phosphoesterase CEP44 PF15007.6 EAX88438.1 - 1e-08 35.4 0.0 14 5.8 0.0 6.9 1 1 7 8 8 8 0 Centrosomal spindle body, CEP44 Staphylokinase PF02821.16 EAX88438.1 - 4.4e-06 27.1 3.1 12 6.4 0.1 5.6 1 1 2 4 4 4 1 Staphylokinase/Streptokinase family ThiS-like PF14453.6 EAX88438.1 - 5.5e-05 23.1 11.5 5.1 7.2 0.1 7.1 5 2 3 8 8 8 2 ThiS-like ubiquitin Ribosomal_S6 PF01250.17 EAX88438.1 - 0.00011 22.3 0.5 20 5.5 0.0 5.4 1 1 6 7 7 7 0 Ribosomal protein S6 B5 PF03484.15 EAX88438.1 - 0.00063 20.0 0.7 72 3.8 0.0 5.9 6 2 0 6 6 6 0 tRNA synthetase B5 domain AnkUBD PF18418.1 EAX88438.1 - 0.00066 19.8 0.0 49 4.2 0.0 4.7 2 2 3 5 5 5 0 Ankyrin ubiquitin-binding domain DUF4512 PF14975.6 EAX88438.1 - 0.0027 18.4 0.4 13 6.6 0.0 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4512) UPF0122 PF04297.14 EAX88438.1 - 0.027 14.7 0.3 83 3.5 0.0 3.5 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like Ank_2 PF12796.7 EAX88439.1 - 1.1e-18 67.6 0.2 8.7e-10 39.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88439.1 - 4.7e-17 62.1 0.3 1.2e-08 35.3 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88439.1 - 4.4e-12 46.0 0.1 5.4e-08 33.0 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88439.1 - 1.3e-11 43.7 0.2 0.00072 19.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX88439.1 - 9.3e-09 35.4 0.0 0.0037 17.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 EAX88439.1 - 5.3e-06 26.3 5.0 0.016 15.2 0.3 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) FAD_binding_5 PF00941.21 EAX88439.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase NUDIX PF00293.28 EAX88440.1 - 2.2e-13 50.4 0.0 3.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 EAX88440.1 - 3.1e-11 43.1 0.2 5.1e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain DNA_primase_S PF01896.19 EAX88441.1 - 3.5e-40 137.9 0.7 4.9e-40 137.4 0.7 1.2 1 0 0 1 1 1 1 DNA primase small subunit GRAM PF02893.20 EAX88442.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.8 EAX88442.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 CobD_Cbib PF03186.13 EAX88442.1 - 0.053 12.7 0.2 0.096 11.9 0.2 1.4 1 0 0 1 1 1 0 CobD/Cbib protein Reticulon PF02453.17 EAX88442.1 - 0.29 11.1 7.8 0.23 11.4 2.2 2.3 2 0 0 2 2 2 0 Reticulon RRM_1 PF00076.22 EAX88443.1 - 0.0051 16.6 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EAX88446.1 - 9e-15 55.7 0.0 1.6e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 EAX88448.1 - 0.00015 21.5 0.1 0.00039 20.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX88448.1 - 0.03 14.1 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EAX88448.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair Myb_DNA-binding PF00249.31 EAX88448.1 - 0.12 12.6 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4477 PF14780.6 EAX88449.1 - 1.9e-07 30.9 2.1 2.8e-07 30.4 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) ESAG1 PF03238.13 EAX88449.1 - 0.015 14.7 0.7 0.024 14.1 0.7 1.4 1 0 0 1 1 1 0 ESAG protein DUF3463 PF11946.8 EAX88449.1 - 0.075 12.8 1.1 5.3 6.9 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3463) ubiquitin PF00240.23 EAX88450.1 - 2e-32 110.7 0.5 2.8e-32 110.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EAX88450.1 - 2.1e-23 81.9 10.1 3.3e-23 81.3 10.1 1.2 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EAX88450.1 - 2.2e-18 65.8 0.8 3.1e-18 65.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX88450.1 - 0.00011 22.6 0.1 0.00036 20.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX88450.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX88450.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EAX88450.1 - 0.069 13.7 0.1 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain HypA PF01155.19 EAX88450.1 - 0.075 13.1 3.2 0.12 12.4 3.2 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ubiquitin_4 PF18036.1 EAX88450.1 - 0.096 12.8 2.6 3.9 7.6 0.1 2.4 3 0 0 3 3 3 0 Ubiquitin-like domain zinc_ribbon_2 PF13240.6 EAX88450.1 - 2.5 7.9 6.9 14 5.5 3.9 3.1 2 1 0 2 2 2 0 zinc-ribbon domain DUF4551 PF15087.6 EAX88451.1 - 0.37 9.6 9.1 0.34 9.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_L7Ae PF01248.26 EAX88453.1 - 1.1e-18 66.7 0.0 1.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TMEM154 PF15102.6 EAX88454.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EAX88454.1 - 0.022 15.0 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 EAX88454.1 - 0.048 13.4 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) UL45 PF05473.12 EAX88454.1 - 0.078 12.6 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DAP10 PF07213.11 EAX88454.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 DAP10 membrane protein RRM_1 PF00076.22 EAX88456.1 - 0.12 12.2 0.0 8.2 6.3 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borealin PF10512.9 EAX88457.1 - 0.11 12.5 2.5 3.5 7.6 0.3 2.1 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 B_solenoid_dext PF18841.1 EAX88457.1 - 0.15 12.4 5.8 4.2 7.7 0.4 2.2 2 0 0 2 2 2 0 Beta solenoid repeat from Dextranase ODV-E18 PF10717.9 EAX88457.1 - 1 9.3 3.8 0.34 10.8 0.8 1.8 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF5071 PF16804.5 EAX88458.1 - 0.16 12.3 1.8 0.39 11.0 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) Adaptin_N PF01602.20 EAX88459.1 - 2.9e-83 280.2 7.0 4e-83 279.8 7.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX88459.1 - 0.0053 16.8 7.8 0.77 9.8 1.6 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RICTOR_M PF14666.6 EAX88459.1 - 0.19 11.5 1.8 3.3 7.5 0.3 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain HEAT PF02985.22 EAX88459.1 - 0.24 11.8 6.4 38 4.9 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF2572 PF10833.8 EAX88459.1 - 5 6.8 7.4 4.8 6.9 3.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2572) DUF4108 PF13390.6 EAX88460.1 - 3.2e-62 208.7 5.6 3.5e-62 208.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX88462.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX88462.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX88462.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX88462.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX88463.1 - 7.3e-35 119.2 0.2 1.9e-34 117.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX88463.1 - 0.041 14.5 0.0 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX88464.1 - 3.4e-07 30.8 0.3 6.1e-07 29.9 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX88464.1 - 0.12 13.1 0.4 0.36 11.5 0.4 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Herpes_BBRF1 PF04793.12 EAX88465.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein Cyclin PF08613.11 EAX88466.1 - 3.4e-07 30.8 0.1 4.2e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EAX88466.1 - 0.00043 20.0 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF5100 PF17029.5 EAX88466.1 - 0.041 13.7 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) PKD_channel PF08016.12 EAX88467.1 - 0.0021 16.8 6.9 0.0021 16.8 6.9 1.7 1 1 0 2 2 2 1 Polycystin cation channel RasGEF PF00617.19 EAX88468.1 - 7.3e-35 120.8 1.3 1.7e-34 119.6 0.1 2.2 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EAX88468.1 - 9.6e-09 35.4 0.9 3.6e-08 33.6 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif TetR_C_5 PF08360.11 EAX88468.1 - 0.27 11.4 1.4 5.7 7.1 0.0 2.8 3 0 0 3 3 3 0 QacR-like protein, C-terminal region PSP PF04046.16 EAX88469.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88470.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX88471.1 - 0.035 14.6 0.5 0.09 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FAS_N PF17828.1 EAX88472.1 - 0.0049 16.9 0.1 0.0075 16.3 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DinB PF05163.12 EAX88472.1 - 0.089 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 DinB family DUF4413 PF14372.6 EAX88473.1 - 0.14 12.6 0.0 8.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) EcoEI_R_C PF08463.10 EAX88474.1 - 0.056 13.6 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal Mlo PF03094.15 EAX88474.1 - 0.076 11.4 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Mlo family Shugoshin_N PF07558.11 EAX88475.1 - 0.0084 16.0 2.1 0.0084 16.0 2.1 3.9 4 0 0 4 4 4 1 Shugoshin N-terminal coiled-coil region FAM76 PF16046.5 EAX88475.1 - 0.13 11.6 30.5 0.29 10.5 7.5 2.3 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 EAX88475.1 - 0.27 10.1 47.9 0.43 9.4 7.2 3.8 3 1 1 4 4 4 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.13 EAX88475.1 - 0.33 11.1 0.1 0.33 11.1 0.1 3.4 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal DASH_Dad3 PF08656.10 EAX88475.1 - 0.37 10.9 0.1 0.37 10.9 0.1 4.3 3 2 0 3 3 3 0 DASH complex subunit Dad3 DUF4407 PF14362.6 EAX88475.1 - 1.7 7.9 20.3 0.27 10.6 6.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EAX88475.1 - 2.5 8.5 35.8 5 7.5 0.2 3.4 2 1 1 3 3 3 0 Fez1 GAS PF13851.6 EAX88475.1 - 4.3 6.6 42.3 5.9 6.2 4.7 3.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EAX88475.1 - 4.5 7.3 23.6 0.69 10.0 7.2 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 EAX88475.1 - 9.8 5.1 43.1 0.85 8.6 15.9 2.7 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_5 PF13306.6 EAX88476.1 - 6.4e-65 216.9 49.2 3.4e-27 94.9 10.8 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88476.1 - 1.9e-16 59.5 1.6 0.021 14.6 0.1 7.4 4 2 5 9 9 9 5 Leucine rich repeat HHH_3 PF12836.7 EAX88476.1 - 0.17 12.2 0.0 35 4.8 0.0 3.7 5 0 0 5 5 5 0 Helix-hairpin-helix motif FNIP PF05725.12 EAX88476.1 - 0.87 9.8 7.4 57 4.0 0.3 4.7 4 0 0 4 4 4 0 FNIP Repeat DUF563 PF04577.14 EAX88477.1 - 5.8e-30 105.0 3.7 8.4e-30 104.5 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ubiquitin PF00240.23 EAX88478.1 - 2.8e-08 33.4 0.0 7.7e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2247 PF10004.9 EAX88478.1 - 0.11 12.3 1.7 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF3403 PF11883.8 EAX88478.1 - 0.11 12.6 1.6 2.5 8.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) Guanylate_cyc PF00211.20 EAX88479.1 - 2.7e-28 98.9 0.1 6.1e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX88479.1 - 0.0039 17.4 0.3 0.038 14.2 0.1 2.7 2 0 0 2 2 2 1 PAS domain SKN1 PF03935.15 EAX88479.1 - 0.083 11.3 3.3 3.3 6.0 0.2 2.3 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) RNA_pol_N PF01194.17 EAX88481.1 - 0.25 11.7 1.9 3.5 8.0 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit LRR_5 PF13306.6 EAX88482.1 - 8.4e-44 148.6 36.3 2.7e-24 85.5 10.2 4.0 2 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88482.1 - 4.7e-11 42.3 0.4 0.036 13.8 0.0 4.4 2 1 1 4 4 4 3 Leucine rich repeat Gly-zipper_Omp PF13488.6 EAX88483.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX88483.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX88483.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Apolipoprotein PF01442.18 EAX88484.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pox_A32 PF04665.12 EAX88485.1 - 3e-05 23.6 3.1 3.4e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX88485.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX88485.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX88485.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4107 PF13389.6 EAX88486.1 - 4e-50 170.2 6.1 6.7e-50 169.4 6.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX88486.1 - 0.077 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DNA_pol_B_2 PF03175.13 EAX88487.1 - 1.5e-26 93.3 8.4 2.8e-26 92.4 8.4 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral CENP-F_leu_zip PF10473.9 EAX88489.1 - 0.00074 19.5 3.0 0.00087 19.3 2.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAD_binding_9 PF13454.6 EAX88489.1 - 0.029 14.4 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding PspA_IM30 PF04012.12 EAX88489.1 - 0.032 13.8 3.1 0.059 12.9 3.1 1.4 1 1 0 1 1 1 0 PspA/IM30 family SlyX PF04102.12 EAX88490.1 - 0.11 13.1 4.4 0.15 12.7 4.1 1.4 1 1 0 1 1 1 0 SlyX DUF4108 PF13390.6 EAX88492.1 - 2.4e-62 209.1 6.1 2.7e-62 208.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX88493.1 - 0.00052 19.5 2.3 0.00077 19.0 2.3 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX88493.1 - 0.0096 15.6 0.2 0.013 15.1 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX88493.1 - 0.051 13.3 0.2 0.38 10.5 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX88493.1 - 0.059 12.9 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4588 PF15251.6 EAX88493.1 - 0.095 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Aminotran_1_2 PF00155.21 EAX88495.1 - 4.3e-31 108.4 0.0 5.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PSP PF04046.16 EAX88496.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88497.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX88498.1 - 0.078 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX88499.1 - 1.7e-06 28.5 0.2 9e-06 26.2 0.2 2.1 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX88499.1 - 0.0044 16.8 0.2 0.032 14.1 0.0 2.4 2 2 0 2 2 2 1 KilA-N domain DUF2203 PF09969.9 EAX88500.1 - 1.6 9.5 6.2 21 5.9 0.3 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Cupin_5 PF06172.11 EAX88502.1 - 2.6e-35 121.7 0.0 2.8e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) SAS-6_N PF16531.5 EAX88503.1 - 1.8e-09 38.0 2.2 1.8e-09 38.0 2.2 2.6 3 0 0 3 3 3 1 Centriolar protein SAS N-terminal Filament PF00038.21 EAX88503.1 - 4.8e-05 23.1 50.8 4.8e-05 23.1 50.8 2.9 1 1 1 2 2 2 1 Intermediate filament protein Mce4_CUP1 PF11887.8 EAX88503.1 - 0.0036 16.8 2.7 0.0036 16.8 2.7 2.4 2 1 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative SlyX PF04102.12 EAX88503.1 - 0.0039 17.8 9.1 0.0039 17.8 9.1 6.5 1 1 5 6 6 6 1 SlyX TMF_DNA_bd PF12329.8 EAX88503.1 - 0.01 15.8 7.2 0.01 15.8 7.2 6.8 2 1 5 7 7 7 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EAX88503.1 - 0.011 15.5 4.7 0.011 15.5 4.7 6.8 1 1 5 6 6 6 0 Septum formation initiator PKcGMP_CC PF16808.5 EAX88503.1 - 0.29 11.0 27.7 0.3 11.0 1.5 6.2 5 1 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YvrJ PF12841.7 EAX88503.1 - 0.35 10.4 5.8 11 5.6 0.1 4.2 4 0 0 4 4 4 0 YvrJ protein family Spc7 PF08317.11 EAX88503.1 - 1.2 7.9 74.0 0.24 10.3 18.7 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAX88503.1 - 1.4 6.3 67.7 0.51 7.8 30.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LRR_5 PF13306.6 EAX88504.1 - 4.5e-110 362.9 67.6 1e-31 109.5 10.3 6.0 2 2 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88504.1 - 4.3e-21 74.4 3.4 0.0085 15.8 0.0 9.0 7 2 2 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 EAX88504.1 - 4.2e-05 23.8 14.0 4.4 7.9 0.1 8.5 7 3 3 10 10 10 2 Leucine Rich repeats (2 copies) Hexapep_2 PF14602.6 EAX88504.1 - 0.089 12.6 0.1 0.63 9.9 0.1 2.6 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Cadherin_pro PF08758.11 EAX88504.1 - 0.23 11.6 0.7 8.8 6.6 0.1 3.6 3 1 0 3 3 3 0 Cadherin prodomain like AAL_decarboxy PF03306.13 EAX88505.1 - 8.5e-44 149.5 0.1 9.6e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase DUF29 PF01724.16 EAX88506.1 - 0.016 15.5 3.0 0.047 13.9 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF29 Picorna_P3A PF06363.11 EAX88507.1 - 0.13 12.1 2.4 12 5.9 0.5 2.8 2 1 1 3 3 3 0 Picornaviridae P3A protein Ank_4 PF13637.6 EAX88509.1 - 1.3e-14 54.3 0.1 4.6e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88509.1 - 1.9e-12 47.1 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX88509.1 - 3e-11 43.2 1.7 3.9e-07 30.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX88509.1 - 5.3e-10 39.8 0.2 8.1e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88509.1 - 4e-09 36.0 0.1 2.2e-06 27.5 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat LEM PF03020.15 EAX88509.1 - 0.012 15.2 0.0 0.67 9.6 0.0 2.5 3 0 0 3 3 3 0 LEM domain Ish1 PF10281.9 EAX88509.1 - 0.055 13.8 0.6 0.15 12.4 0.0 2.0 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Hormone_3 PF00159.18 EAX88509.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Pancreatic hormone peptide EAF PF09816.9 EAX88510.1 - 1.3e-06 28.8 0.2 1.5e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cadherin_tail PF15974.5 EAX88511.1 - 0.0065 16.8 0.0 0.0078 16.5 0.0 1.1 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region TMEM154 PF15102.6 EAX88511.1 - 0.018 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF997 PF06196.12 EAX88511.1 - 0.022 14.7 2.1 0.032 14.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) FixH PF05751.11 EAX88511.1 - 0.098 12.7 3.2 0.17 11.9 3.2 1.3 1 0 0 1 1 1 0 FixH DUF5305 PF17231.2 EAX88511.1 - 0.098 12.0 0.2 0.14 11.5 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 EAX88511.1 - 0.12 12.3 2.5 0.19 11.7 2.5 1.2 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.11 EAX88511.1 - 0.13 11.9 2.8 0.2 11.2 2.8 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Pilin_N PF07790.11 EAX88511.1 - 0.13 13.2 2.9 0.21 12.5 0.8 2.0 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ASFV_J13L PF05568.11 EAX88511.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 EAX88511.1 - 0.16 12.8 0.6 0.25 12.2 0.6 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 EAX88511.1 - 0.17 12.0 0.5 0.23 11.5 0.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Orf78 PF06024.12 EAX88511.1 - 0.33 11.3 3.1 0.33 11.3 3.1 1.3 1 1 0 1 1 1 0 Orf78 (ac78) TPPK_C PF12555.8 EAX88511.1 - 2.4 8.3 9.2 4.2 7.5 9.2 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal YhdB PF14148.6 EAX88512.1 - 0.11 12.6 1.0 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 YhdB-like protein HTH_57 PF18679.1 EAX88512.1 - 0.23 11.8 2.5 0.54 10.6 0.5 2.3 1 1 1 2 2 2 0 ThcOx helix turn helix domain PTS_EIIA_2 PF00359.22 EAX88512.1 - 0.41 10.6 5.2 0.89 9.5 0.2 2.9 2 1 1 3 3 3 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF3837 PF12939.7 EAX88512.1 - 1.5 9.3 7.8 0.4 11.1 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3837) AAA_31 PF13614.6 EAX88512.1 - 1.8 8.5 7.5 2.9 7.8 1.8 2.3 1 1 0 2 2 2 0 AAA domain MIT PF04212.18 EAX88512.1 - 3.9 7.6 7.2 8.1 6.6 0.6 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Cauli_DNA-bind PF03310.13 EAX88512.1 - 9 6.4 14.3 0.53 10.4 3.6 2.4 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein LPD5 PF18799.1 EAX88512.1 - 9.1 6.7 10.9 3.3 8.1 6.2 2.1 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 B56 PF01603.20 EAX88513.1 - 9.4e-69 232.4 13.1 1.1e-68 232.1 13.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Fur_reg_FbpB PF13040.6 EAX88513.1 - 0.026 14.1 0.8 10 5.8 0.2 2.7 2 0 0 2 2 2 0 Fur-regulated basic protein B Ammonium_transp PF00909.21 EAX88514.1 - 2.4e-27 95.7 33.8 4.1e-27 94.9 33.8 1.3 1 1 0 1 1 1 1 Ammonium Transporter Family IBD PF10416.9 EAX88515.1 - 1.4e-16 60.7 0.1 3.8e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PSP PF04046.16 EAX88516.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88517.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX88520.1 - 3.6e-156 517.8 13.4 4.5e-156 517.4 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88520.1 - 0.12 12.8 2.2 0.44 11.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX88520.1 - 0.16 11.8 2.2 0.33 10.8 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX88520.1 - 0.2 12.0 2.2 0.57 10.5 0.9 2.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit T5orf172 PF10544.9 EAX88521.1 - 2.4e-06 28.0 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX88521.1 - 0.014 15.2 1.3 0.042 13.7 0.5 2.2 2 1 0 2 2 2 0 KilA-N domain DUF2939 PF11159.8 EAX88522.1 - 0.032 14.7 0.3 0.049 14.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX88522.1 - 2 7.4 4.1 2.2 7.3 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX88522.1 - 8.8 6.3 7.4 9.5 6.2 7.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAX88523.1 - 0.096 12.7 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) BspA_v PF18220.1 EAX88524.1 - 0.99 9.5 6.4 3.1 7.9 1.3 2.3 2 0 0 2 2 2 0 Adhesin BspA variable domain LBR_tudor PF09465.10 EAX88526.1 - 0.00046 19.9 0.3 0.00084 19.1 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX88526.1 - 0.092 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Spi protease inhibitor Pox_A32 PF04665.12 EAX88528.1 - 3.6e-08 33.2 0.1 4.9e-08 32.7 0.1 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein ER PF01133.17 EAX88528.1 - 0.11 12.5 1.0 0.23 11.5 1.0 1.5 1 0 0 1 1 1 0 Enhancer of rudimentary DUF4107 PF13389.6 EAX88530.1 - 3.6e-51 173.5 1.1 4.2e-51 173.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX88533.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX88534.1 - 2.1e-71 239.3 3.4 2.7e-71 239.0 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX88535.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX88536.1 - 1.2e-153 509.4 12.7 1.6e-153 509.1 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88536.1 - 0.84 10.1 6.4 1.6 9.2 0.3 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX88536.1 - 1.2 9.7 5.0 0.99 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4108 PF13390.6 EAX88537.1 - 0.0014 18.6 7.8 0.0017 18.3 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phi-29_GP4 PF05464.11 EAX88537.1 - 0.07 13.4 1.4 0.15 12.3 0.3 2.0 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Trypan_PARP PF05887.11 EAX88538.1 - 0.11 12.4 8.4 0.17 11.9 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88538.1 - 3.5 8.1 5.7 5 7.6 5.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX88539.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88539.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX88540.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX88541.1 - 9.6e-148 490.2 11.4 1.3e-147 489.7 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88541.1 - 0.011 16.2 2.4 0.033 14.6 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX88541.1 - 0.23 12.0 3.5 4.7 7.7 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX88541.1 - 0.97 10.0 5.8 1 9.9 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) RasGAP PF00616.19 EAX88543.1 - 2.1e-09 37.4 0.0 1.8e-07 31.1 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase HTH_AsnC-type PF13404.6 EAX88543.1 - 0.014 15.2 0.3 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cytokin_check_N PF10407.9 EAX88543.1 - 0.62 10.1 5.2 25 4.9 0.1 3.5 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus WD40 PF00400.32 EAX88544.1 - 1.2e-30 105.1 21.7 3.8e-06 27.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX88544.1 - 2.4e-08 34.2 1.0 0.015 15.6 0.0 4.4 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FeThRed_A PF02941.15 EAX88544.1 - 1.8e-05 24.8 0.1 0.79 9.9 0.0 3.5 2 1 1 3 3 3 2 Ferredoxin thioredoxin reductase variable alpha chain PQQ PF01011.21 EAX88544.1 - 0.0058 16.5 0.9 0.06 13.3 0.1 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat Coatomer_WDAD PF04053.14 EAX88544.1 - 0.032 13.3 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region WD40_like PF17005.5 EAX88544.1 - 0.055 12.8 0.0 0.49 9.7 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 EAX88544.1 - 1.8 9.1 7.4 14 6.3 0.1 4.0 4 1 0 4 4 4 0 PQQ-like domain Hema_HEFG PF02710.14 EAX88545.1 - 0.065 13.4 0.0 0.83 9.9 0.0 2.4 2 1 0 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein TB2_DP1_HVA22 PF03134.19 EAX88546.1 - 1.5e-21 76.0 5.8 2.3e-21 75.5 5.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GPS2_interact PF15784.5 EAX88547.1 - 0.026 14.9 1.5 0.035 14.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88547.1 - 0.12 11.4 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX88548.1 - 0.13 12.2 7.6 0.21 11.6 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX88549.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX88550.1 - 0.03 14.7 0.5 0.042 14.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX88550.1 - 2.1 8.4 5.5 2.3 8.3 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX88551.1 - 0.049 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX88552.1 - 5.9e-31 107.8 12.0 3.5e-30 105.3 11.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.7 EAX88553.1 - 1.1e-06 29.2 0.0 0.0051 17.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88553.1 - 0.00032 20.9 0.0 6.1 7.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX88553.1 - 0.013 16.1 0.5 2.1 9.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) KRTAP7 PF15034.6 EAX88553.1 - 0.1 13.5 0.4 0.25 12.4 0.0 1.7 2 0 0 2 2 2 0 KRTAP type 7 family DSHCT PF08148.12 EAX88554.1 - 6.1e-41 139.8 1.1 2e-40 138.1 0.1 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EAX88554.1 - 4.5e-18 65.6 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX88554.1 - 3.9e-05 24.0 0.0 0.00017 21.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX88554.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAX88554.1 - 0.033 13.3 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_pol_A_exo1 PF01612.20 EAX88555.1 - 2.7e-06 27.2 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Adeno_E3_CR2 PF02439.15 EAX88556.1 - 0.13 12.1 3.7 0.19 11.5 3.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PSP PF04046.16 EAX88557.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Shisa PF13908.6 EAX88560.1 - 0.0016 18.8 0.3 0.0016 18.8 0.3 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EAX88560.1 - 0.021 15.1 0.6 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) MG2 PF01835.19 EAX88560.1 - 0.068 13.6 0.2 0.59 10.6 0.1 2.5 3 0 0 3 3 3 0 MG2 domain bMG6 PF17962.1 EAX88560.1 - 0.077 13.2 1.0 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 RAMP4 PF06624.12 EAX88560.1 - 0.11 12.5 0.6 0.47 10.6 0.3 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF4366 PF14283.6 EAX88561.1 - 0.00074 19.6 0.4 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF5305 PF17231.2 EAX88561.1 - 0.0022 17.4 0.0 0.0022 17.4 0.0 2.3 4 0 0 4 4 4 1 Family of unknown function (DUF5305) DUF4448 PF14610.6 EAX88561.1 - 0.005 16.7 0.1 0.005 16.7 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) DUF5385 PF17359.2 EAX88561.1 - 0.024 14.2 0.6 0.047 13.2 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF5129 PF17173.4 EAX88561.1 - 0.058 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF1687 PF07955.11 EAX88561.1 - 0.059 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) DUF3112 PF11309.8 EAX88561.1 - 0.095 12.1 1.2 0.15 11.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) FeoB_associated PF12669.7 EAX88561.1 - 0.13 12.7 5.2 0.26 11.7 5.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3149 PF11346.8 EAX88561.1 - 0.16 11.6 0.9 0.32 10.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) WD40 PF00400.32 EAX88562.1 - 2.6e-08 34.4 6.4 0.11 13.4 0.2 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX88562.1 - 6.2e-06 26.4 0.0 0.11 12.8 0.0 2.8 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Rep_fac_C PF08542.11 EAX88563.1 - 2.1e-16 60.1 0.0 9.3e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 EAX88563.1 - 1.4e-15 57.9 0.0 2.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAX88563.1 - 2.1e-12 47.1 0.1 6.7e-11 42.2 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EAX88563.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAX88563.1 - 2.7e-07 30.7 0.0 8.9e-07 29.0 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EAX88563.1 - 4.9e-06 26.9 0.1 0.0014 18.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EAX88563.1 - 6e-06 26.7 0.1 0.00011 22.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EAX88563.1 - 3.1e-05 23.5 0.0 0.00026 20.5 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EAX88563.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX88563.1 - 0.00011 22.6 0.1 0.00096 19.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAX88563.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EAX88563.1 - 0.00044 19.9 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EAX88563.1 - 0.00044 20.1 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 EAX88563.1 - 0.00056 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAX88563.1 - 0.0011 18.9 0.3 0.0091 16.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAX88563.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAX88563.1 - 0.0025 18.2 0.0 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_assoc_2 PF16193.5 EAX88563.1 - 0.0029 17.9 0.4 0.013 15.8 0.0 2.2 2 1 1 3 3 1 1 AAA C-terminal domain RuvB_N PF05496.12 EAX88563.1 - 0.0031 17.3 0.1 0.009 15.8 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EAX88563.1 - 0.0035 17.9 0.1 0.0086 16.6 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EAX88563.1 - 0.0039 17.7 0.0 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EAX88563.1 - 0.0041 17.0 1.3 0.067 13.1 0.1 2.5 1 1 1 2 2 2 1 NTPase ATPase_2 PF01637.18 EAX88563.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea MeaB PF03308.16 EAX88563.1 - 0.0074 15.3 0.1 0.028 13.4 0.0 1.9 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 EAX88563.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein T2SSE PF00437.20 EAX88563.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EAX88563.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.9 EAX88563.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 EAX88563.1 - 0.018 15.3 0.2 0.046 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EAX88563.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 EAX88563.1 - 0.033 13.7 0.0 0.087 12.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EAX88563.1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 EAX88563.1 - 0.037 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 EAX88563.1 - 0.046 13.7 0.0 2.8 7.9 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 EAX88563.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 EAX88563.1 - 0.05 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAX88563.1 - 0.06 13.5 0.2 0.21 11.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EAX88563.1 - 0.068 13.1 0.1 0.36 10.7 0.1 2.3 2 1 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EAX88563.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAX88563.1 - 0.14 11.4 0.1 0.6 9.3 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Metallophos PF00149.28 EAX88564.1 - 2.1e-32 113.3 0.8 4.2e-32 112.3 0.1 1.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX88564.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FYVE_2 PF02318.16 EAX88565.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger GAS PF13851.6 EAX88567.1 - 0.00011 21.6 24.5 0.00011 21.6 24.5 4.3 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EAX88567.1 - 0.0033 17.7 3.1 0.0033 17.7 3.1 6.7 2 2 4 7 7 7 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 EAX88567.1 - 0.0055 16.8 3.7 0.0055 16.8 3.7 6.2 1 1 4 6 6 6 2 Designed helical repeat protein 10 domain BRE1 PF08647.11 EAX88567.1 - 0.0074 16.3 16.1 0.0074 16.3 16.1 5.1 2 2 2 4 4 4 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EAX88567.1 - 0.026 15.0 17.7 0.026 15.0 17.7 5.3 1 1 3 4 4 4 0 Apg6 coiled-coil region zf-MIZ PF02891.20 EAX88568.1 - 4e-16 58.5 0.3 8e-16 57.5 0.1 1.6 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAX88568.1 - 0.0023 17.7 0.2 0.0063 16.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DNA_pol_E_B PF04042.16 EAX88568.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Zn_Tnp_IS1595 PF12760.7 EAX88568.1 - 0.074 13.0 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ank_4 PF13637.6 EAX88569.1 - 1e-47 159.9 14.8 1.4e-10 41.4 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88569.1 - 1.4e-41 141.0 26.1 5.5e-18 65.3 1.3 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88569.1 - 5e-40 134.2 11.0 1.3e-07 31.7 0.0 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX88569.1 - 2.2e-33 110.5 10.9 0.00019 21.6 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX88569.1 - 2.8e-33 113.5 17.0 1e-08 35.3 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Env-gp36 PF09590.10 EAX88569.1 - 0.21 10.0 4.9 1.8 6.9 0.9 2.0 1 1 0 2 2 2 0 Lentivirus surface glycoprotein NapB PF03892.14 EAX88569.1 - 0.37 10.8 4.1 0.21 11.6 0.5 2.1 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Thioredoxin PF00085.20 EAX88571.1 - 4.9e-16 58.6 2.0 1.8e-15 56.8 0.5 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX88571.1 - 0.0004 20.8 2.7 0.0085 16.5 0.2 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EAX88571.1 - 0.0014 18.5 1.5 0.0042 17.0 0.2 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX88571.1 - 0.0062 16.8 4.8 2 8.8 0.0 4.4 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAX88571.1 - 0.0098 16.1 0.1 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EAX88571.1 - 0.029 14.1 0.1 0.44 10.3 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin Pkinase PF00069.25 EAX88572.1 - 3.3e-58 197.2 0.1 4.4e-58 196.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88572.1 - 5.2e-31 107.9 0.1 1.3e-29 103.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX88572.1 - 0.00049 20.1 0.0 0.0027 17.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PriCT_1 PF08708.11 EAX88572.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Primase C terminal 1 (PriCT-1) RIO1 PF01163.22 EAX88572.1 - 0.0035 17.0 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.11 EAX88572.1 - 0.0097 15.5 3.7 0.036 13.7 3.7 2.0 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 EAX88572.1 - 0.038 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nore1-SARAH PF16517.5 EAX88572.1 - 0.085 12.8 1.3 0.36 10.8 1.3 2.1 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Amidoligase_2 PF12224.8 EAX88572.1 - 0.094 12.4 0.9 0.43 10.2 0.3 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme Ank_2 PF12796.7 EAX88574.1 - 2.5e-12 47.2 0.7 8.9e-07 29.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88574.1 - 7.7e-06 25.9 1.2 0.016 15.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX88574.1 - 0.0012 19.1 0.0 0.18 12.2 0.0 3.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX88574.1 - 0.0046 17.4 0.3 2 9.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeat CTD PF12815.7 EAX88574.1 - 0.0059 17.2 19.7 7.2e+02 0.8 0.0 6.2 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Ank_4 PF13637.6 EAX88574.1 - 0.0087 16.6 0.7 2.2 8.9 0.8 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Dpy-30 PF05186.13 EAX88575.1 - 0.00031 20.4 0.3 0.0012 18.5 0.3 1.8 1 1 0 1 1 1 1 Dpy-30 motif bZIP_1 PF00170.21 EAX88575.1 - 0.0094 16.0 1.7 0.0094 16.0 1.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor MCC-bdg_PDZ PF10506.9 EAX88575.1 - 0.034 14.2 0.6 0.053 13.5 0.6 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1690 PF07956.11 EAX88575.1 - 0.048 14.1 1.1 0.05 14.0 1.1 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) FlaC_arch PF05377.11 EAX88575.1 - 0.07 13.5 0.7 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) VPS11_C PF12451.8 EAX88575.1 - 0.092 13.0 0.0 5 7.4 0.5 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF5582 PF17819.1 EAX88575.1 - 0.19 12.2 0.5 0.19 12.2 0.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5582) MutS_V PF00488.21 EAX88576.1 - 1e-33 116.9 0.0 2.8e-33 115.5 0.0 1.7 2 0 0 2 2 1 1 MutS domain V MutS_III PF05192.18 EAX88576.1 - 5.4e-21 75.7 1.0 1.3e-20 74.5 1.0 1.7 1 0 0 1 1 1 1 MutS domain III ATPase_2 PF01637.18 EAX88576.1 - 0.00011 22.2 0.9 0.024 14.6 0.1 3.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DHC_N2 PF08393.13 EAX88576.1 - 0.00038 19.7 2.3 0.0009 18.5 2.3 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_23 PF13476.6 EAX88576.1 - 0.0006 20.4 0.3 0.0006 20.4 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAX88576.1 - 0.00067 19.9 0.5 0.08 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EAX88576.1 - 0.0022 17.8 0.1 0.0065 16.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EAX88576.1 - 0.0031 18.0 1.0 0.014 15.9 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 EAX88576.1 - 0.0034 17.8 0.2 0.078 13.4 0.0 3.0 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EAX88576.1 - 0.0069 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EAX88576.1 - 0.0093 16.0 2.0 0.036 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAX88576.1 - 0.0096 16.3 0.1 0.11 12.9 0.1 2.5 2 1 0 3 3 3 1 AAA ATPase domain DAP3 PF10236.9 EAX88576.1 - 0.011 14.9 0.0 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 U3snoRNP10 PF12397.8 EAX88576.1 - 0.012 16.0 3.0 2.4 8.5 0.4 3.2 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 NAAA-beta PF15508.6 EAX88576.1 - 0.015 15.6 0.3 9.7 6.6 0.0 3.4 3 0 0 3 3 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SMC_N PF02463.19 EAX88576.1 - 0.017 14.5 0.1 0.07 12.6 0.1 2.1 2 0 0 2 2 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EAX88576.1 - 0.035 14.0 3.5 0.57 10.1 0.3 3.5 2 2 0 2 2 2 0 Rad17 P-loop domain T2SSF PF00482.23 EAX88576.1 - 0.051 13.5 0.0 0.61 10.1 0.0 2.5 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein F AAA_27 PF13514.6 EAX88576.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX88576.1 - 0.07 12.8 0.0 0.65 9.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX88576.1 - 0.086 11.9 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EAX88576.1 - 0.096 13.1 0.6 0.62 10.5 0.0 2.7 2 2 0 2 2 2 0 RNA helicase NACHT PF05729.12 EAX88576.1 - 0.16 11.9 0.4 0.81 9.6 0.1 2.3 3 0 0 3 3 2 0 NACHT domain DUF1043 PF06295.12 EAX88576.1 - 0.55 10.2 2.1 5.1 7.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 EAX88576.1 - 0.93 9.5 12.8 0.45 10.6 0.8 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2408 PF10303.9 EAX88576.1 - 2 9.0 7.6 0.92 10.1 0.5 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF2408) Ank_2 PF12796.7 EAX88578.1 - 1.1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88578.1 - 2e-05 25.0 0.0 2.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88578.1 - 0.00032 21.0 0.0 0.00045 20.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88578.1 - 0.0054 17.1 0.0 0.06 13.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX88578.1 - 0.083 13.4 0.0 5.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat FliJ PF02050.16 EAX88579.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein GPS2_interact PF15784.5 EAX88580.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88580.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX88581.1 - 0.047 13.7 8.7 0.064 13.2 8.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX88582.1 - 0.024 14.7 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX88583.1 - 0.02 15.3 0.4 0.023 15.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX88584.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Ank_4 PF13637.6 EAX88587.1 - 9.9e-20 70.7 13.2 1.3e-07 32.0 1.1 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88587.1 - 3e-19 69.4 8.1 4.2e-12 46.5 3.1 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88587.1 - 1.1e-18 65.3 8.1 0.00087 19.6 0.2 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX88587.1 - 2.5e-17 62.7 2.8 6e-06 26.4 0.2 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX88587.1 - 4.1e-13 49.1 14.8 0.0041 17.5 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 EAX88587.1 - 7.6e-09 35.4 0.9 7.6e-09 35.4 0.9 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) RNA_polI_A14 PF08203.11 EAX88588.1 - 0.11 13.3 0.2 0.53 11.1 0.2 2.2 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF3785 PF12653.7 EAX88588.1 - 0.42 10.7 4.6 0.21 11.7 1.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3785) GGA_N-GAT PF18308.1 EAX88588.1 - 2 8.1 7.6 0.94 9.2 1.2 3.3 4 0 0 4 4 4 0 GGA N-GAT domain Nrap_D6 PF17407.2 EAX88589.1 - 0.13 12.5 0.2 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Nrap protein domain 6 PDEase_I PF00233.19 EAX88590.1 - 8.6e-80 267.9 0.2 1.8e-79 266.9 0.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX88590.1 - 2.4e-33 115.6 0.0 4.4e-13 50.0 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX88590.1 - 1.1e-27 97.0 0.0 8.1e-12 45.6 0.0 4.6 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 EAX88590.1 - 1.2e-19 70.9 0.0 1.2e-07 32.1 0.0 3.7 3 0 0 3 3 3 3 GAF domain H_kinase_N PF12282.8 EAX88590.1 - 0.021 14.8 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Signal transduction histidine kinase DWNN PF08783.11 EAX88591.1 - 2.6e-18 66.1 1.6 6.4e-18 64.8 1.6 1.7 1 0 0 1 1 1 1 DWNN domain U-box PF04564.15 EAX88591.1 - 0.00034 20.7 0.1 0.0012 18.9 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 EAX88591.1 - 0.0037 17.1 9.8 0.0063 16.3 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAX88591.1 - 0.0072 16.2 11.0 0.013 15.3 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX88591.1 - 0.33 10.8 10.7 0.66 9.9 10.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX88591.1 - 2 8.5 8.9 4.4 7.4 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EAX88591.1 - 3.5 7.5 11.7 8.8 6.2 11.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2897 PF11446.8 EAX88592.1 - 1.2 9.0 3.2 2.5 8.0 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAX88593.1 - 3.2e-11 43.1 34.9 2.4e-08 33.9 5.6 5.5 5 1 0 5 5 5 3 Phage tail repeat like EMP24_GP25L PF01105.24 EAX88593.1 - 0.099 12.6 5.9 11 5.9 3.4 3.6 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Amidase02_C PF12123.8 EAX88594.1 - 0.0024 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88595.1 - 3e-72 242.1 3.6 3.9e-72 241.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX88595.1 - 0.12 12.8 0.5 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta RRM_1 PF00076.22 EAX88596.1 - 9.6e-16 57.4 0.2 3.1e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX88596.1 - 1.8e-07 30.8 0.0 7.4e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX88596.1 - 3.8e-05 23.5 0.0 0.009 15.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RrnaAD PF00398.20 EAX88596.1 - 0.041 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Orf78 PF06024.12 EAX88597.1 - 2.7e-05 24.4 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) DUF4448 PF14610.6 EAX88597.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 EAX88597.1 - 0.012 15.0 3.2 0.02 14.3 3.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4366 PF14283.6 EAX88597.1 - 0.021 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CrgA PF06781.12 EAX88597.1 - 0.074 13.1 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Cell division protein CrgA DUF3242 PF11586.8 EAX88597.1 - 0.18 11.5 3.3 0.4 10.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Guanylate_cyc PF00211.20 EAX88598.1 - 1.5e-43 148.5 0.1 3.2e-43 147.5 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX88598.1 - 6.1e-06 26.4 0.4 2.9e-05 24.2 0.4 2.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX88598.1 - 1e-05 25.5 0.0 2.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX88598.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 EAX88598.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain HNOBA PF07701.14 EAX88598.1 - 0.084 12.3 0.6 12 5.3 0.1 2.7 2 0 0 2 2 2 0 Heme NO binding associated Lectin_N PF03954.14 EAX88598.1 - 0.12 12.1 0.2 0.4 10.4 0.2 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1772 PF08592.11 EAX88598.1 - 7.9 6.8 6.6 17 5.7 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Ank_2 PF12796.7 EAX88599.1 - 1.8e-47 159.8 12.7 1.2e-12 48.2 0.7 6.4 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88599.1 - 9.1e-42 140.9 12.6 2.8e-10 40.5 0.3 9.0 6 2 4 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88599.1 - 1.3e-40 136.0 20.2 4.2e-05 23.8 0.1 11.0 11 1 1 12 12 12 8 Ankyrin repeat Ank_3 PF13606.6 EAX88599.1 - 5.3e-37 121.6 16.6 0.0002 21.5 0.1 12.1 12 1 1 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 EAX88599.1 - 6.9e-30 102.7 12.6 1.9e-09 37.6 1.2 8.3 3 2 6 9 9 9 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88599.1 - 2.7e-26 91.3 10.4 2.7e-26 91.3 10.4 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) LRR_5 PF13306.6 EAX88601.1 - 8.6e-50 168.0 58.9 7.9e-20 71.1 19.9 5.1 1 1 4 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88601.1 - 1.3e-08 34.4 1.1 3.1 7.6 0.0 7.5 4 3 4 8 8 7 3 Leucine rich repeat SAS-6_N PF16531.5 EAX88602.1 - 3.4e-13 50.0 0.7 3.4e-13 50.0 0.7 4.1 2 1 0 3 3 3 1 Centriolar protein SAS N-terminal AAA_13 PF13166.6 EAX88602.1 - 0.00017 20.4 55.4 0.0079 14.9 39.2 2.1 1 1 0 2 2 2 2 AAA domain Spc7 PF08317.11 EAX88602.1 - 0.0011 18.0 67.4 0.011 14.6 17.6 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EAX88602.1 - 0.0071 16.3 10.0 0.0071 16.3 10.0 5.8 1 1 3 6 6 6 2 TATA element modulatory factor 1 DNA binding TetR_C_24 PF17932.1 EAX88602.1 - 0.037 14.3 2.0 0.26 11.6 0.4 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Filament PF00038.21 EAX88602.1 - 0.046 13.3 63.8 0.2 11.2 18.8 3.3 1 1 2 3 3 3 0 Intermediate filament protein DUF948 PF06103.11 EAX88602.1 - 0.24 11.7 26.9 1.1 9.6 1.8 4.7 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.8 EAX88602.1 - 0.27 8.7 58.4 0.11 10.0 46.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EAX88602.1 - 0.47 10.5 44.2 0.065 13.3 4.0 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Transthyretin PF00576.21 EAX88602.1 - 0.84 10.3 8.8 0.15 12.8 2.1 2.8 1 1 1 2 2 2 0 HIUase/Transthyretin family DUF2353 PF09789.9 EAX88602.1 - 2.2 7.6 56.9 0.55 9.5 8.9 3.2 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF812 PF05667.11 EAX88602.1 - 4.5 6.0 67.1 4.7 6.0 32.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Jnk-SapK_ap_N PF09744.9 EAX88602.1 - 6.7 6.9 71.7 4.3 7.6 18.6 4.5 1 1 4 5 5 5 0 JNK_SAPK-associated protein-1 FPP PF05911.11 EAX88602.1 - 7.1 4.7 69.0 3.3 5.8 32.7 2.6 1 1 1 2 2 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 EAX88602.1 - 9.6 6.5 63.7 0.054 13.7 6.2 5.1 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding C2 PF00168.30 EAX88603.1 - 0.0059 16.9 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain DcpS_C PF11969.8 EAX88604.1 - 0.33 11.4 4.2 4.4 7.8 0.1 2.4 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding VPS13 PF16908.5 EAX88605.1 - 7.7e-39 133.9 0.3 3.7e-38 131.7 0.3 2.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EAX88605.1 - 1.7e-20 73.3 1.9 2.6e-20 72.6 0.2 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 EAX88605.1 - 0.0003 20.3 10.2 0.0013 18.2 0.7 4.5 4 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 EAX88605.1 - 0.00047 20.0 1.2 0.12 12.1 0.4 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EAX88605.1 - 0.0016 18.8 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ANAPC4_WD40 PF12894.7 EAX88606.1 - 7e-05 23.1 0.0 3.2 8.1 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EAX88606.1 - 0.17 12.1 0.1 6.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LAGLIDADG_1 PF00961.19 EAX88606.1 - 2.8 9.0 5.8 7.9 7.5 0.8 3.2 3 0 0 3 3 3 0 LAGLIDADG endonuclease Myb_DNA-binding PF00249.31 EAX88607.1 - 6.5e-25 87.1 0.2 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88607.1 - 8e-20 70.8 0.2 1.3e-09 38.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX88607.1 - 8.4e-07 28.8 3.4 4.2e-06 26.6 0.0 2.8 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX88607.1 - 0.00053 20.0 0.8 0.28 11.2 0.2 2.8 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX88607.1 - 0.013 15.7 0.4 1.1 9.5 0.1 3.1 2 2 0 2 2 2 0 Rap1 Myb domain HxlR PF01638.17 EAX88607.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Rap1_C PF11626.8 EAX88607.1 - 0.097 12.8 0.1 2.8 8.1 0.1 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Na_sulph_symp PF00939.19 EAX88608.1 - 4.8e-22 78.6 41.1 7.1e-22 78.1 41.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAX88608.1 - 6.2e-16 58.4 43.5 5e-08 32.5 25.3 2.3 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 EAX88608.1 - 0.00036 20.6 15.2 0.0094 15.9 2.7 3.1 2 1 1 3 3 3 2 SPX domain Peptidase_C10 PF01640.17 EAX88608.1 - 0.44 10.8 0.1 0.44 10.8 0.1 1.9 3 0 0 3 3 3 0 Peptidase C10 family DUF4625 PF15418.6 EAX88609.1 - 0.0001 22.5 18.9 0.03 14.6 0.1 8.4 8 1 1 9 9 9 2 Domain of unknown function (DUF4625) TMEM154 PF15102.6 EAX88609.1 - 0.0069 16.3 0.1 0.023 14.6 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family ODV-E18 PF10717.9 EAX88609.1 - 0.019 14.8 0.1 0.054 13.4 0.1 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syndecan PF01034.20 EAX88609.1 - 0.034 14.1 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 EAX88609.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EAX88609.1 - 0.066 14.1 0.0 0.31 11.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Putative_G5P PF17426.2 EAX88609.1 - 0.096 12.8 0.8 0.37 10.9 0.2 2.4 2 0 0 2 2 2 0 Putative Gamma DNA binding protein G5P DUF2970 PF11174.8 EAX88609.1 - 0.15 11.9 2.3 0.27 11.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF2897 PF11446.8 EAX88610.1 - 0.41 10.6 2.8 0.87 9.5 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX88611.1 - 1.4e-64 216.3 6.3 1.6e-64 216.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RasGAP PF00616.19 EAX88612.1 - 0.00019 21.2 1.1 0.00046 20.0 0.9 1.7 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase AAA_29 PF13555.6 EAX88613.1 - 0.19 11.5 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EAX88613.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain S_layer_N PF05123.12 EAX88616.1 - 0.064 13.1 0.2 0.064 13.1 0.2 1.5 2 0 0 2 2 2 0 S-layer like family, N-terminal region DUF4795 PF16043.5 EAX88618.1 - 0.00013 21.6 0.4 0.00032 20.4 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF4988 PF16378.5 EAX88618.1 - 0.0035 17.0 0.6 0.007 16.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function Sipho_Gp157 PF05565.11 EAX88618.1 - 0.0046 17.0 0.7 0.15 12.0 0.0 2.2 2 0 0 2 2 2 1 Siphovirus Gp157 Vps51 PF08700.11 EAX88618.1 - 0.011 15.8 0.9 0.027 14.6 0.9 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Prefoldin PF02996.17 EAX88618.1 - 0.026 14.5 1.1 0.06 13.3 1.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 EAX88618.1 - 0.033 14.4 1.8 0.033 14.4 1.8 3.0 3 0 0 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 EAX88618.1 - 0.044 14.2 2.1 0.044 14.2 2.1 2.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 EAX88618.1 - 0.064 13.4 2.0 0.064 13.4 2.0 1.7 2 0 0 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.20 EAX88618.1 - 1.8 8.5 9.5 0.59 10.1 3.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit Biotin_carb_C PF02785.19 EAX88619.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain EpuA PF11772.8 EAX88620.1 - 0.015 15.0 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX88620.1 - 0.093 12.8 12.7 0.13 12.4 0.3 3.9 4 1 0 4 4 4 0 Phage tail repeat like DUF1947 PF09183.10 EAX88620.1 - 0.14 12.5 4.0 0.88 9.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) DUF3791 PF12668.7 EAX88621.1 - 0.016 15.2 0.1 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) SLBP_RNA_bind PF15247.6 EAX88622.1 - 0.091 12.9 0.4 0.42 10.8 0.5 1.8 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain DUF4108 PF13390.6 EAX88623.1 - 1.7e-06 28.0 2.3 1.9e-06 27.8 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Endopep_inhib PF16800.5 EAX88623.1 - 0.017 15.0 0.2 0.019 14.9 0.2 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Amidase02_C PF12123.8 EAX88624.1 - 0.0024 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX88626.1 - 9.7e-152 503.3 14.3 1.1e-151 503.0 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88626.1 - 0.35 11.4 4.9 1.3 9.5 0.2 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX88627.1 - 3.5e-12 46.2 0.2 5.7e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain NTS PF15447.6 EAX88627.1 - 0.17 12.4 3.2 1.8 9.2 0.9 2.4 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 ubiquitin PF00240.23 EAX88628.1 - 0.071 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family TFIIF_beta_N PF17683.1 EAX88629.1 - 0.064 13.9 0.5 0.082 13.6 0.5 1.2 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus MucBP PF06458.12 EAX88629.1 - 0.085 13.9 0.8 0.14 13.2 0.3 1.6 1 1 0 1 1 1 0 MucBP domain BUD22 PF09073.10 EAX88629.1 - 0.09 12.1 14.8 0.11 11.9 14.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EAX88629.1 - 0.77 7.9 15.6 0.81 7.8 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAX88629.1 - 1.1 7.4 15.2 1.1 7.4 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TSA PF03249.13 EAX88629.1 - 1.5 7.5 5.5 1.9 7.2 5.5 1.1 1 0 0 1 1 1 0 Type specific antigen NOA36 PF06524.12 EAX88629.1 - 1.5 8.1 16.1 1.8 7.8 16.1 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EAX88629.1 - 2.5 7.6 14.9 3 7.4 14.9 1.1 1 0 0 1 1 1 0 PPP4R2 COPI_C PF06957.11 EAX88629.1 - 3.6 6.2 7.1 4.5 5.9 7.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DNA_pol_phi PF04931.13 EAX88629.1 - 5.8 4.9 19.0 7.2 4.6 19.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_P85_iSH2 PF16454.5 EAX88630.1 - 0.0005 19.7 6.1 0.00059 19.5 6.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SKA2 PF16740.5 EAX88630.1 - 0.011 15.5 0.3 0.011 15.5 0.3 2.0 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FadA PF09403.10 EAX88630.1 - 0.014 15.8 3.2 0.014 15.8 3.2 1.7 1 1 1 2 2 2 0 Adhesion protein FadA POLO_box PF00659.18 EAX88630.1 - 0.017 15.3 1.7 0.024 14.8 0.5 1.7 2 0 0 2 2 2 0 POLO box duplicated region DUF16 PF01519.16 EAX88630.1 - 0.036 14.5 5.2 0.05 14.1 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 PI_PP_I PF18363.1 EAX88630.1 - 0.039 14.1 4.3 0.22 11.7 0.2 2.1 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF1465 PF07323.12 EAX88630.1 - 0.063 13.1 0.4 0.85 9.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) PCRF PF03462.18 EAX88630.1 - 0.098 12.5 3.6 0.22 11.4 2.9 1.7 1 1 1 2 2 2 0 PCRF domain Plk4_PB2 PF18409.1 EAX88630.1 - 0.1 13.3 1.9 1.2 9.8 0.2 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Rad51 PF08423.11 EAX88630.1 - 0.12 11.6 0.3 0.13 11.5 0.3 1.1 1 0 0 1 1 1 0 Rad51 ZapB PF06005.12 EAX88630.1 - 0.19 12.2 5.4 0.79 10.2 5.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EAX88630.1 - 0.27 11.0 8.1 0.11 12.3 3.0 2.2 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 EAX88630.1 - 0.28 11.5 7.5 0.54 10.6 2.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 EAX88630.1 - 0.5 8.9 6.6 0.15 10.6 3.2 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A Laminin_II PF06009.12 EAX88630.1 - 0.64 10.0 5.0 1.8 8.6 1.3 2.4 1 1 1 2 2 2 0 Laminin Domain II LMBR1 PF04791.16 EAX88630.1 - 0.69 8.8 2.4 0.69 8.8 2.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HALZ PF02183.18 EAX88630.1 - 1.2 9.4 8.9 0.17 12.2 3.1 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper LAGLIDADG_1 PF00961.19 EAX88630.1 - 2.1 9.4 7.8 0.3 12.1 1.7 2.2 1 1 0 2 2 2 0 LAGLIDADG endonuclease LOH1CR12 PF10158.9 EAX88630.1 - 2.2 8.3 5.6 8.6 6.4 1.4 2.1 1 1 0 2 2 2 0 Tumour suppressor protein DUF3899 PF13038.6 EAX88630.1 - 4.6 7.8 5.5 13 6.4 5.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) Ank_2 PF12796.7 EAX88631.1 - 1.6e-40 137.6 18.8 1.5e-15 57.5 2.7 4.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX88631.1 - 2e-40 136.6 7.2 2e-40 136.6 7.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX88631.1 - 2.4e-31 107.7 12.2 6.5e-12 45.7 0.2 7.2 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX88631.1 - 7.1e-27 92.6 11.1 1.8e-06 28.1 0.1 5.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX88631.1 - 2e-24 83.0 11.0 2.5e-05 24.3 0.0 6.7 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX88631.1 - 9.2e-22 76.8 6.2 2.9e-08 33.8 0.3 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) TMP PF05017.14 EAX88633.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88634.1 - 0.095 12.6 1.2 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 PSP RicinB_lectin_2 PF14200.6 EAX88635.1 - 0.0051 17.5 0.0 0.0077 16.9 0.0 1.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like MIR PF02815.19 EAX88635.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 MIR domain Glyco_hydro_16 PF00722.21 EAX88636.1 - 1e-17 64.1 10.6 2.4e-17 63.0 10.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAX88636.1 - 0.0007 18.1 14.9 0.0076 14.7 1.7 3.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Big_3_4 PF13754.6 EAX88636.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Sigma_reg_N PF13800.6 EAX88637.1 - 0.03 14.6 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2621 PF11084.8 EAX88637.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) PspB PF06667.12 EAX88637.1 - 0.078 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B PAP_PilO PF06864.12 EAX88637.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4448 PF14610.6 EAX88637.1 - 0.57 9.9 3.9 19 5.0 3.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) TPR_1 PF00515.28 EAX88639.1 - 6e-24 82.8 1.6 4.1e-06 26.4 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAX88639.1 - 3.3e-22 76.8 9.0 0.00044 20.1 0.0 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAX88639.1 - 5e-15 55.5 5.3 0.0041 17.4 0.0 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAX88639.1 - 9.5e-15 54.0 4.8 0.51 11.3 0.0 7.7 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAX88639.1 - 4.5e-14 52.7 3.6 0.032 14.7 0.0 5.9 2 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAX88639.1 - 1.1e-12 47.0 0.4 0.074 13.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX88639.1 - 1.5e-12 46.9 10.4 0.026 14.9 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX88639.1 - 2.4e-12 45.9 1.1 0.059 13.4 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX88639.1 - 4.3e-12 46.5 5.8 4.4e-05 24.0 0.0 5.5 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EAX88639.1 - 9.7e-11 41.4 2.5 0.016 14.4 0.0 4.7 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAX88639.1 - 4.1e-10 39.6 6.5 0.65 10.8 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAX88639.1 - 7e-09 35.7 1.0 0.0011 19.1 0.1 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX88639.1 - 5.1e-08 32.5 0.0 0.12 12.1 0.0 5.3 4 1 2 6 6 6 3 TPR repeat TPR_10 PF13374.6 EAX88639.1 - 2e-06 27.5 6.8 0.24 11.4 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX88639.1 - 0.00029 21.0 9.0 0.058 13.6 0.2 4.1 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.9 EAX88639.1 - 0.00047 19.7 2.6 0.061 12.8 0.0 2.8 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain Coatomer_E PF04733.14 EAX88639.1 - 0.002 17.6 0.1 2.5 7.4 0.1 2.7 2 1 1 3 3 3 2 Coatomer epsilon subunit MIT PF04212.18 EAX88639.1 - 0.0032 17.5 0.7 7.1 6.8 0.0 4.3 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 EAX88639.1 - 0.0032 16.5 2.4 0.062 12.3 0.0 2.9 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 EAX88639.1 - 2.5 7.6 5.6 2.3 7.8 0.1 3.7 4 0 0 4 4 4 0 SHNi-TPR Ribosomal_L18 PF17135.4 EAX88640.1 - 2e-75 252.3 0.3 2.2e-75 252.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EAX88640.1 - 0.0011 19.7 0.0 0.0017 19.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CLN3 PF02487.17 EAX88642.1 - 4.8e-27 95.0 17.0 9.2e-26 90.8 17.0 2.0 1 1 0 1 1 1 1 CLN3 protein Gly-zipper_Omp PF13488.6 EAX88643.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX88643.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX88643.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX88643.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX88643.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 EAX88644.1 - 1.1e-29 102.1 0.0 1.6e-19 69.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EAX88644.1 - 0.00062 19.9 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 2 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 EAX88644.1 - 0.0059 16.6 0.1 0.25 11.4 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EAX88644.1 - 0.0076 15.8 0.7 0.89 9.2 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPH PF13868.6 EAX88645.1 - 5.9e-08 31.6 146.8 5.9e-08 31.6 146.8 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain COPI_assoc PF08507.10 EAX88646.1 - 0.00013 22.0 8.6 0.00015 21.8 8.6 1.0 1 0 0 1 1 1 1 COPI associated protein Helicase_C_2 PF13307.6 EAX88647.1 - 5.7e-48 163.3 0.0 9.5e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EAX88647.1 - 1.8e-07 31.1 0.4 0.0044 16.7 0.0 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EAX88648.1 - 9.9e-05 22.4 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EAX88648.1 - 0.012 15.1 0.4 0.032 13.8 0.0 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 EAX88648.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EAX88648.1 - 0.072 12.7 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX88648.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Peptidase_S28 PF05577.12 EAX88649.1 - 1.5e-82 277.7 0.8 2.1e-82 277.3 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Laminin_EGF PF00053.24 EAX88649.1 - 0.4 10.9 2.8 0.54 10.5 0.6 2.2 2 0 0 2 2 2 0 Laminin EGF domain Peptidase_M15_2 PF05951.13 EAX88650.1 - 0.11 12.1 2.7 1.8 8.2 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) Ldh_1_C PF02866.18 EAX88650.1 - 0.13 12.1 0.4 3.4 7.6 0.0 2.6 3 0 0 3 3 3 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Gly_rich PF12810.7 EAX88651.1 - 3.9e-48 164.5 37.2 5e-48 164.1 37.2 1.0 1 0 0 1 1 1 1 Glycine rich protein DDE_Tnp_ISL3 PF01610.17 EAX88652.1 - 2e-05 24.4 0.2 4.3e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Transposase Adeno_E1B_55K PF01696.17 EAX88652.1 - 0.038 12.7 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen zf-C2H2_assoc2 PF16624.5 EAX88652.1 - 7.1 7.7 10.8 0.12 13.4 1.8 2.5 3 0 0 3 3 3 0 Unstructured region upstream of a zinc-finger Trypan_PARP PF05887.11 EAX88653.1 - 0.03 14.3 8.3 0.047 13.7 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88653.1 - 3.7 8.0 5.1 5.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX88654.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88654.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF4108 PF13390.6 EAX88657.1 - 6.8e-78 259.5 12.3 7.8e-78 259.3 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Beach PF02138.18 EAX88658.1 - 2.4e-77 260.0 3.8 6.2e-77 258.7 3.8 1.8 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EAX88658.1 - 0.29 12.1 2.0 12 7.0 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Gly_rich PF12810.7 EAX88659.1 - 3.7e-50 171.1 47.6 9e-50 169.9 47.6 1.5 1 1 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAX88660.1 - 2.2e-07 30.7 3.8 1.1e-05 25.2 0.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88660.1 - 0.0045 17.6 0.0 0.06 13.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88660.1 - 0.042 14.4 0.0 0.51 11.0 0.0 2.6 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88660.1 - 0.095 13.3 0.0 33 5.5 0.0 3.8 4 1 1 5 5 5 0 Ankyrin repeat Ras PF00071.22 EAX88661.1 - 1e-53 181.2 0.2 1.3e-53 180.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88661.1 - 1.4e-31 109.2 0.3 2.7e-31 108.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88661.1 - 6.1e-19 68.1 0.1 7.3e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX88661.1 - 9.1e-10 38.3 0.1 1.1e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88661.1 - 1.4e-08 34.8 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX88661.1 - 7.7e-08 32.1 0.6 3.6e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX88661.1 - 8.8e-06 25.7 1.1 0.019 14.9 0.2 2.6 1 1 2 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 EAX88661.1 - 3.6e-05 23.9 0.0 4.8e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EAX88661.1 - 5.4e-05 22.6 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 EAX88661.1 - 0.00011 21.9 0.1 0.00017 21.3 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAX88661.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EAX88661.1 - 0.0011 18.6 1.4 0.092 12.3 0.1 2.3 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 EAX88661.1 - 0.0012 17.8 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ATP_bind_1 PF03029.17 EAX88661.1 - 0.0012 18.7 1.0 0.11 12.3 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EAX88661.1 - 0.0039 17.5 0.4 0.0089 16.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 EAX88661.1 - 0.016 14.6 0.4 0.061 12.6 0.4 2.0 1 1 0 1 1 1 0 AIG1 family AAA PF00004.29 EAX88661.1 - 0.017 15.5 0.2 0.033 14.6 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX88661.1 - 0.021 15.2 0.3 0.046 14.1 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EAX88661.1 - 0.022 14.7 0.3 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAX88661.1 - 0.035 13.6 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX88661.1 - 0.038 13.7 0.4 0.084 12.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EAX88661.1 - 0.079 12.9 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EAX88661.1 - 0.097 13.2 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX88661.1 - 0.13 12.3 0.7 0.52 10.3 0.7 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TolA_bind_tri PF16331.5 EAX88662.1 - 0.017 15.2 1.9 0.017 15.2 1.9 8.1 4 4 4 8 8 8 0 TolA binding protein trimerisation Brr6_like_C_C PF10104.9 EAX88662.1 - 0.33 10.7 2.2 2.1 8.2 2.2 2.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Mce4_CUP1 PF11887.8 EAX88662.1 - 0.56 9.6 6.2 0.29 10.6 1.1 2.8 1 1 2 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative HAD_SAK_2 PF18143.1 EAX88663.1 - 0.0099 16.2 0.0 0.044 14.1 0.0 2.1 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins AAA_26 PF13500.6 EAX88663.1 - 0.039 13.8 0.1 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF4106 PF13388.6 EAX88664.1 - 5.7e-275 912.0 19.4 5.7e-275 912.0 19.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) Aldose_epim PF01263.20 EAX88667.1 - 7.4e-25 87.9 0.2 1.8e-24 86.6 0.2 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_38C PF07748.13 EAX88667.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain PepSY_TM_like_2 PF16357.5 EAX88669.1 - 0.054 13.5 0.1 0.067 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like Pik1 PF11522.8 EAX88669.1 - 0.4 10.7 3.7 2.6 8.1 2.2 2.5 2 1 1 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 zf-UBR PF02207.20 EAX88670.1 - 9.7e-10 38.5 14.9 9.7e-10 38.5 14.9 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-C3H2C3 PF17122.5 EAX88670.1 - 7.9 6.6 10.9 0.092 12.8 1.8 2.3 2 0 0 2 2 2 0 Zinc-finger DUF3839 PF12943.7 EAX88672.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Trypan_PARP PF05887.11 EAX88673.1 - 0.035 14.1 9.5 0.049 13.6 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX88674.1 - 0.091 13.2 1.5 0.12 12.8 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain L27_1 PF09058.10 EAX88675.1 - 0.0081 16.1 3.0 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 L27_1 CREPT PF16566.5 EAX88675.1 - 0.03 14.5 1.7 0.036 14.2 0.2 1.9 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX88675.1 - 0.069 13.2 0.4 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 EAX88676.1 - 2.5e-125 409.3 98.9 7.1e-18 65.0 6.0 8.3 2 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88676.1 - 3.6e-91 298.5 36.8 2.1e-12 47.3 0.1 13.4 3 1 11 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX88676.1 - 3.6e-85 277.0 35.7 1.4e-06 28.4 0.1 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 EAX88676.1 - 9.6e-73 231.4 37.9 2.3e-05 24.4 0.1 14.9 16 0 0 16 16 15 11 Ankyrin repeat Ank_5 PF13857.6 EAX88676.1 - 1e-56 188.2 44.5 2.3e-09 37.3 0.4 9.1 5 3 7 12 12 12 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88676.1 - 2.8e-36 123.3 10.4 2.9e-36 123.3 6.4 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) YcxB PF14317.6 EAX88676.1 - 1e-16 60.4 0.0 1.6 8.5 0.0 11.2 1 1 10 11 11 11 1 YcxB-like protein Usp PF00582.26 EAX88676.1 - 3.5e-09 37.3 11.3 32 5.0 0.1 9.7 1 1 10 11 11 11 0 Universal stress protein family ThiS-like PF14453.6 EAX88676.1 - 3e-06 27.2 30.4 4.5 7.4 0.4 10.3 1 1 10 11 11 11 3 ThiS-like ubiquitin Cupin_7 PF12973.7 EAX88676.1 - 0.00027 20.8 3.9 2.8 7.9 0.0 6.6 4 4 4 8 8 8 1 ChrR Cupin-like domain Amidase PF01425.21 EAX88676.1 - 0.00041 19.4 4.1 15 4.4 0.0 6.0 2 1 4 7 7 7 0 Amidase DUF4122 PF13498.6 EAX88676.1 - 0.011 15.4 0.1 37 3.9 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4122) Lysozyme_like PF13702.6 EAX88676.1 - 0.28 10.9 28.4 27 4.4 0.5 7.9 2 2 1 8 8 8 0 Lysozyme-like HTH_8 PF02954.19 EAX88676.1 - 0.5 10.2 13.1 2.2e+02 1.7 0.0 7.5 7 0 0 7 7 7 0 Bacterial regulatory protein, Fis family DUF3023 PF11224.8 EAX88676.1 - 0.63 9.9 5.7 6.5 6.6 0.2 4.4 3 2 1 5 5 5 0 Protein of unknown function (DUF3023) Raptor_N PF14538.6 EAX88677.1 - 2.6e-13 50.2 3.8 1.5e-12 47.6 0.1 3.0 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain Mcl1_mid PF12341.8 EAX88677.1 - 0.068 12.5 0.2 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Hydrolase_4 PF12146.8 EAX88678.1 - 2.3e-19 69.6 0.0 1.3e-11 44.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX88678.1 - 1.8e-12 47.5 0.2 2.7e-09 37.1 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EAX88678.1 - 3.4e-08 33.4 0.0 2.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EAX88678.1 - 0.00032 20.4 0.0 0.00057 19.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EAX88678.1 - 0.00073 20.2 0.0 0.00095 19.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EAX88678.1 - 0.0026 16.5 0.0 0.0057 15.4 0.0 1.5 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EAX88678.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EAX88678.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase DLH PF01738.18 EAX88678.1 - 0.024 14.2 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 EAX88678.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EAX88678.1 - 0.041 13.2 0.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PhoPQ_related PF10142.9 EAX88678.1 - 0.063 11.9 0.1 0.1 11.2 0.1 1.4 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Asp2 PF16929.5 EAX88678.1 - 0.072 12.1 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter partial_CstF PF15861.5 EAX88679.1 - 0.064 13.1 1.0 0.16 11.8 0.4 1.9 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain DUF3839 PF12943.7 EAX88681.1 - 1.5e-26 93.4 5.8 2.3e-26 92.8 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX88681.1 - 0.07 13.4 0.7 0.3 11.4 0.7 2.1 1 1 0 1 1 1 0 PRD domain APC_u14 PF16635.5 EAX88681.1 - 0.16 12.5 1.5 0.26 11.9 1.5 1.3 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Pex2_Pex12 PF04757.14 EAX88682.1 - 0.048 13.2 0.1 0.058 13.0 0.1 1.1 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region REF PF05755.12 EAX88682.1 - 0.083 12.7 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) PapD_N PF00345.20 EAX88684.1 - 0.049 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX88684.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX88685.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX88685.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX88686.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX88687.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX88687.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX88688.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88688.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Vac14_Fab1_bd PF12755.7 EAX88690.1 - 0.018 15.6 1.9 0.47 11.1 0.0 4.4 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region DHC_N1 PF08385.12 EAX88690.1 - 0.025 13.2 0.3 0.64 8.6 0.0 2.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 HEAT PF02985.22 EAX88690.1 - 0.052 13.8 1.0 1 9.8 0.0 3.8 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 EAX88690.1 - 0.084 12.9 21.2 1.3 9.0 0.4 6.5 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 EAX88690.1 - 0.14 12.1 0.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) VHS PF00790.19 EAX88690.1 - 0.15 11.9 3.3 23 4.8 0.1 3.8 4 1 1 5 5 5 0 VHS domain IBN_N PF03810.19 EAX88690.1 - 1.5 8.8 6.0 5.1 7.1 0.7 3.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain TIP120 PF08623.10 EAX88690.1 - 5.4 6.8 7.2 3.6 7.3 0.0 3.9 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) Clat_adaptor_s PF01217.20 EAX88691.1 - 5.4e-49 165.8 3.0 6e-49 165.6 3.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Myb_DNA-binding PF00249.31 EAX88692.1 - 4.2e-23 81.3 7.8 1.8e-09 37.6 0.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88692.1 - 1.8e-22 79.3 8.6 2.8e-08 33.9 0.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX88692.1 - 2.6e-07 30.4 21.5 0.0012 18.6 0.1 4.6 4 1 0 4 4 3 3 Myb DNA-binding like ubiquitin PF00240.23 EAX88692.1 - 6.6e-06 25.8 0.2 1.7e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin family Rap1_C PF11626.8 EAX88692.1 - 1.2e-05 25.3 0.1 0.41 10.8 0.0 3.8 3 2 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2052 PF09747.9 EAX88692.1 - 0.00088 19.5 35.2 0.037 14.2 2.3 3.2 3 0 0 3 3 3 3 Coiled-coil domain containing protein (DUF2052) UBA PF00627.31 EAX88692.1 - 0.0034 17.2 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RR_TM4-6 PF06459.12 EAX88692.1 - 0.017 15.0 33.8 0.59 9.9 8.8 3.2 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 EAX88692.1 - 0.62 9.9 35.5 0.65 9.8 1.3 2.9 2 1 1 3 3 3 0 SpoIIIAH-like protein Sigma70_ner PF04546.13 EAX88692.1 - 3 7.7 23.7 1.2 8.9 3.3 3.4 3 0 0 3 3 3 0 Sigma-70, non-essential region CCDC106 PF15794.5 EAX88692.1 - 4.8 6.8 42.5 0.65 9.7 7.5 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 EAX88692.1 - 9.3 4.9 32.2 2.8 6.6 5.5 3.1 3 0 0 3 3 3 0 Presenilin Ank PF00023.30 EAX88693.1 - 2e-98 318.9 15.8 5.5e-08 32.9 0.1 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 EAX88693.1 - 1.5e-95 312.4 11.8 6e-09 36.3 0.0 13.4 3 1 10 13 13 13 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88693.1 - 2.3e-94 310.1 53.5 1.4e-14 54.4 1.7 8.6 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88693.1 - 2.3e-92 301.8 33.5 5.7e-12 45.6 0.1 9.4 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88693.1 - 5.8e-78 247.5 22.9 4.7e-06 26.5 0.1 14.1 14 0 0 14 14 14 11 Ankyrin repeat DUF3447 PF11929.8 EAX88693.1 - 1.3e-36 124.3 4.8 3.4e-36 123.1 2.9 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX88693.1 - 3.8e-19 68.7 5.0 1 9.6 0.0 11.1 1 1 8 10 10 10 4 N terminal of Calcineurin-like phosphoesterase Mic1 PF07035.12 EAX88693.1 - 1.4e-09 37.8 4.4 2.8 7.6 0.0 7.4 4 3 2 8 8 8 3 Colon cancer-associated protein Mic1-like RNase_PH_C PF03725.15 EAX88693.1 - 0.00096 19.1 13.4 39 4.4 0.0 7.9 3 3 8 11 11 11 0 3' exoribonuclease family, domain 2 YkuD_2 PF13645.6 EAX88693.1 - 0.0021 17.5 7.9 19 4.7 0.1 7.2 1 1 8 10 10 10 0 L,D-transpeptidase catalytic domain MTES_1575 PF18741.1 EAX88693.1 - 0.072 13.3 6.4 96 3.3 0.0 5.8 2 2 5 8 8 8 0 REase_MTES_1575 PH_8 PF15409.6 EAX88693.1 - 0.32 11.3 8.5 3.5e+02 1.6 0.0 6.9 1 1 7 9 9 9 0 Pleckstrin homology domain YDG PF18657.1 EAX88693.1 - 0.68 10.2 9.1 2.2e+02 2.1 0.1 6.1 1 1 5 7 7 7 0 YDG domain Malate_DH PF12434.8 EAX88693.1 - 0.81 9.8 11.4 24 5.1 0.3 4.2 3 0 0 3 3 3 0 Malate dehydrogenase enzyme PTR PF12789.7 EAX88694.1 - 1.3e-21 76.4 19.5 1.3e-16 60.4 1.9 4.7 6 0 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX88694.1 - 0.043 13.6 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX88694.1 - 0.095 12.6 2.5 1.3 9.0 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) TMP PF05017.14 EAX88696.1 - 0.13 13.0 7.8 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX88696.1 - 4.3 7.3 8.2 4.7 7.2 8.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX88697.1 - 0.11 12.4 2.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX88698.1 - 1.1e-06 29.1 0.1 0.0021 18.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88698.1 - 5.4e-05 23.3 0.0 2.1 9.2 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX88698.1 - 0.00075 20.0 0.1 6.2 7.5 0.0 3.8 5 0 0 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88698.1 - 0.016 15.2 1.5 0.016 15.2 1.5 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3447) C2-C2_1 PF11618.8 EAX88699.1 - 2.1e-05 24.6 0.3 2.1e-05 24.6 0.3 2.1 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 Filament PF00038.21 EAX88699.1 - 9.4e-05 22.1 55.0 0.025 14.2 30.1 3.9 2 1 1 3 3 3 3 Intermediate filament protein DUF5082 PF16888.5 EAX88699.1 - 0.0001 22.6 21.3 0.0001 22.6 21.3 5.0 3 3 2 5 5 5 2 Domain of unknown function (DUF5082) Spc7 PF08317.11 EAX88699.1 - 0.0016 17.4 60.0 0.025 13.5 24.5 3.3 2 1 1 3 3 3 2 Spc7 kinetochore protein ATG16 PF08614.11 EAX88699.1 - 0.0024 18.1 61.6 0.035 14.3 27.8 4.3 3 1 1 4 4 4 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EAX88699.1 - 0.014 15.9 75.5 0.23 12.0 16.3 4.7 2 1 3 5 5 5 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EAX88699.1 - 0.027 14.7 60.7 0.94 9.7 2.4 4.4 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF4482 PF14818.6 EAX88699.1 - 0.031 15.1 3.0 0.031 15.1 3.0 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4482) DivIC PF04977.15 EAX88699.1 - 0.034 13.9 63.8 0.053 13.3 4.6 7.5 5 2 2 7 7 7 0 Septum formation initiator CENP-F_leu_zip PF10473.9 EAX88699.1 - 0.084 12.9 57.7 0.2 11.7 10.1 4.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 EAX88699.1 - 0.096 13.0 30.5 0.38 11.1 1.1 6.4 5 2 2 7 7 6 0 TSC-22/dip/bun family DUF4407 PF14362.6 EAX88699.1 - 0.34 10.2 55.6 1.9 7.8 5.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EAX88699.1 - 0.81 9.8 59.3 1.3 9.1 11.5 4.9 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EAX88699.1 - 1.5 8.6 51.0 0.15 11.9 8.9 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF724) YlqD PF11068.8 EAX88699.1 - 1.8 9.0 53.1 1.8 8.9 1.4 4.9 4 1 1 5 5 5 0 YlqD protein GIT_CC PF16559.5 EAX88699.1 - 3.4 7.6 33.4 0.48 10.3 3.6 5.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor CtIP_N PF10482.9 EAX88699.1 - 3.5 7.7 35.5 0.05 13.6 3.4 3.8 3 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 EAX88699.1 - 5.4 6.3 63.9 1.2 8.4 21.6 4.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 EAX88699.1 - 8.7 4.8 54.8 0.56 8.8 28.6 3.1 2 1 1 3 3 3 0 AAA domain CorA PF01544.18 EAX88700.1 - 0.0018 17.6 0.5 0.0025 17.2 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Arf PF00025.21 EAX88701.1 - 8.7e-58 194.6 0.1 1e-57 194.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX88701.1 - 1.1e-14 54.7 0.1 1.5e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX88701.1 - 2.9e-12 46.5 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EAX88701.1 - 4.2e-10 39.4 0.1 7.5e-10 38.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX88701.1 - 1.2e-07 31.2 0.8 2.2e-06 27.1 0.3 2.2 1 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EAX88701.1 - 2.5e-07 30.8 0.1 3.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX88701.1 - 5.1e-06 26.1 0.1 0.00016 21.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX88701.1 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_pol3_delta2 PF13177.6 EAX88701.1 - 0.037 13.8 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NTNH_C PF08470.10 EAX88701.1 - 0.18 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal PI3_PI4_kinase PF00454.27 EAX88702.1 - 1.5e-49 169.1 0.3 1.5e-49 169.1 0.3 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAX88702.1 - 1.9e-19 70.1 18.0 1.9e-19 70.1 18.0 3.4 1 1 1 2 2 2 1 FAT domain FATC PF02260.20 EAX88702.1 - 1.3e-09 37.7 0.1 8.5e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 FATC domain DUF3385 PF11865.8 EAX88702.1 - 1.2e-07 31.7 0.2 1.2e-07 31.7 0.2 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EAX88702.1 - 0.0012 19.2 0.0 3.1 8.3 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats FRB_dom PF08771.11 EAX88702.1 - 0.023 15.1 0.3 0.023 15.1 0.3 4.2 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain Myb_DNA-binding PF00249.31 EAX88703.1 - 2.6e-12 46.7 0.1 3.2e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88703.1 - 2.7e-11 43.5 1.8 1.7e-10 41.0 1.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PAS_10 PF13596.6 EAX88703.1 - 0.04 14.5 1.2 4.1 8.1 0.3 2.2 2 0 0 2 2 2 0 PAS domain Binary_toxB_3 PF17476.2 EAX88703.1 - 0.049 13.8 0.9 0.085 13.0 0.7 1.5 1 1 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 Ank PF00023.30 EAX88704.1 - 0.058 13.9 1.2 0.31 11.6 1.2 2.2 1 1 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EAX88704.1 - 0.093 13.3 0.1 2.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RRM_1 PF00076.22 EAX88705.1 - 9.3e-31 105.5 0.1 1.7e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAX88705.1 - 2.5e-08 33.9 0.1 0.00097 19.2 0.0 2.3 1 1 1 2 2 2 2 RNA binding motif RRM_7 PF16367.5 EAX88705.1 - 1.3e-06 28.4 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif DUF4651 PF15513.6 EAX88705.1 - 7.2e-05 22.5 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4651) RRM_5 PF13893.6 EAX88705.1 - 0.00038 20.0 0.2 0.0077 15.8 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCBP3 PF10309.9 EAX88705.1 - 0.00072 19.4 1.4 6.3 6.7 0.0 4.3 6 0 0 6 6 6 2 Nuclear cap-binding protein subunit 3 RRM_occluded PF16842.5 EAX88705.1 - 0.0032 17.3 0.1 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EAX88705.1 - 0.0051 17.1 0.0 0.17 12.1 0.0 2.4 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Longin PF13774.6 EAX88705.1 - 0.026 14.5 0.6 0.074 13.1 0.2 2.0 1 1 1 2 2 2 0 Regulated-SNARE-like domain DUF5599 PF18141.1 EAX88705.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) LRR_4 PF12799.7 EAX88706.1 - 6.6e-10 39.1 11.6 0.0011 19.3 0.9 3.7 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX88706.1 - 3.9e-06 26.5 7.7 0.0028 17.4 1.0 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EAX88706.1 - 0.00069 19.2 0.8 0.021 14.3 1.2 2.5 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 EAX88706.1 - 0.00097 19.4 10.9 2.2 9.1 0.6 5.6 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EAX88706.1 - 0.0056 16.6 6.8 2.4 8.4 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat Ank_2 PF12796.7 EAX88707.1 - 4.9e-20 71.9 0.0 1.9e-11 44.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88707.1 - 1.3e-11 44.7 0.0 6.1e-06 26.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88707.1 - 3.5e-09 36.2 0.0 0.023 15.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX88707.1 - 1.8e-08 34.5 0.0 7.8e-05 22.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF2007 PF09413.10 EAX88707.1 - 0.12 12.5 0.0 1 9.6 0.0 2.4 2 1 0 2 2 2 0 Putative prokaryotic signal transducing protein Ank_4 PF13637.6 EAX88708.1 - 4e-45 151.6 9.9 6.8e-11 42.5 0.2 6.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88708.1 - 1.5e-44 150.5 1.6 2.3e-19 69.7 0.2 4.4 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88708.1 - 2.4e-36 123.3 0.2 2.2e-07 31.0 0.1 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88708.1 - 3.6e-31 103.7 0.3 4.8e-05 23.4 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EAX88708.1 - 5.6e-21 74.0 2.8 0.0025 18.2 0.1 6.6 7 0 0 7 7 7 5 Ankyrin repeat YfmQ PF10787.9 EAX88708.1 - 0.018 14.8 0.1 1.9 8.2 0.0 3.2 2 1 0 3 3 3 0 Uncharacterised protein from bacillus cereus group FBD PF08387.10 EAX88708.1 - 0.068 13.1 0.3 4.6 7.2 0.0 2.6 2 1 0 2 2 2 0 FBD EPSP_synthase PF00275.20 EAX88708.1 - 0.19 10.4 0.0 0.43 9.2 0.0 1.5 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) MutL_C PF08676.11 EAX88709.1 - 1e-25 90.3 0.0 1.9e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EAX88709.1 - 9.3e-07 28.8 0.1 2.7e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAX88709.1 - 0.00015 22.2 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EAX88709.1 - 0.00081 19.0 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain CUTL PF16557.5 EAX88709.1 - 0.0024 18.0 0.0 0.017 15.3 0.1 2.4 2 0 0 2 2 2 1 CUT1-like DNA-binding domain of SATB DUF4930 PF16284.5 EAX88709.1 - 0.063 13.2 0.1 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) DUF2263 PF10021.9 EAX88711.1 - 1e-40 139.5 0.0 1.5e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) ATE_C PF04377.15 EAX88711.1 - 0.081 13.5 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Ank_2 PF12796.7 EAX88712.1 - 1.6e-34 118.3 8.1 8e-13 48.8 1.3 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88712.1 - 2.8e-31 107.5 6.2 3.2e-11 43.5 0.0 6.9 5 2 1 6 6 6 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88712.1 - 5.5e-30 103.1 4.3 5.5e-30 103.1 4.3 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX88712.1 - 4e-24 82.1 7.5 0.0036 17.7 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EAX88712.1 - 5.8e-23 80.3 4.3 0.00034 20.9 0.1 8.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX88712.1 - 1.4e-21 76.2 1.3 0.00018 21.7 0.0 6.6 3 1 2 6 6 6 5 Ankyrin repeats (many copies) CNOT1_TTP_bind PF16417.5 EAX88712.1 - 0.0044 16.2 0.7 0.01 15.0 0.7 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF1128 PF06569.11 EAX88712.1 - 0.0094 15.9 0.5 0.22 11.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1128) FERM_C PF09380.10 EAX88713.1 - 0.00029 21.2 0.3 0.00091 19.6 0.3 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain LRR_4 PF12799.7 EAX88713.1 - 0.033 14.6 18.5 0.89 10.1 0.3 4.5 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX88713.1 - 0.93 9.3 9.4 39 4.1 0.1 4.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EAX88713.1 - 3.3 8.0 8.9 7.9 6.8 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat MULE PF10551.9 EAX88714.1 - 3.9e-13 49.6 0.1 8.3e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX88714.1 - 0.22 11.2 4.6 0.3 10.7 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX88714.1 - 0.63 10.3 5.6 1.8 8.9 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX88714.1 - 1.5 8.6 5.3 2.6 7.8 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Lipid_DES PF08557.10 EAX88715.1 - 2 8.0 4.4 0.55 9.8 1.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Mito_fiss_reg PF05308.11 EAX88716.1 - 0.13 12.3 0.4 0.13 12.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator VPS38 PF17649.1 EAX88716.1 - 0.18 10.6 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 CAP_N PF01213.19 EAX88716.1 - 0.68 9.4 2.4 0.67 9.4 2.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KilA-N PF04383.13 EAX88717.1 - 0.00082 19.2 0.1 0.0015 18.3 0.1 1.5 1 1 0 1 1 1 1 KilA-N domain DUF3781 PF12636.7 EAX88720.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) MULE PF10551.9 EAX88722.1 - 1.5e-10 41.3 0.2 4.6e-10 39.8 0.2 1.9 1 0 0 1 1 1 1 MULE transposase domain Drc1-Sld2 PF11719.8 EAX88723.1 - 0.044 13.3 4.6 0.05 13.2 4.6 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein YL1 PF05764.13 EAX88723.1 - 0.077 13.1 6.7 0.088 12.9 6.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EAX88723.1 - 0.1 10.8 4.4 0.11 10.8 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EAX88723.1 - 6.1 4.8 10.5 7.4 4.5 10.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi T5orf172 PF10544.9 EAX88724.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX88725.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX88725.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX88725.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX88725.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX88725.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX88725.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX88725.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX88725.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX88725.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX88725.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX88725.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX88725.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4107 PF13389.6 EAX88729.1 - 9.9e-73 243.6 3.7 1.3e-72 243.3 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2960 PF11173.8 EAX88731.1 - 0.041 14.3 0.3 0.11 13.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Gly_rich PF12810.7 EAX88732.1 - 1.4e-49 169.2 44.1 1.6e-49 169.0 44.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX88734.1 - 2.7e-32 112.6 34.4 3.4e-32 112.3 34.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Beach PF02138.18 EAX88735.1 - 3.9e-94 315.1 5.2 3.9e-94 315.1 5.2 3.1 4 0 0 4 4 4 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EAX88735.1 - 1.2e-05 25.5 0.1 3.1e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EAX88735.1 - 0.00063 19.8 0.3 0.00063 19.8 0.3 6.1 3 2 1 4 4 4 1 PH domain associated with Beige/BEACH Pkinase PF00069.25 EAX88736.1 - 2.8e-72 243.3 0.0 3.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88736.1 - 1.3e-38 132.8 0.0 1.7e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX88736.1 - 1.9e-05 25.1 0.3 0.00013 22.5 0.3 2.2 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX88736.1 - 9e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 EAX88736.1 - 0.0016 19.1 1.2 0.003 18.2 1.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EAX88736.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX88736.1 - 0.091 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAX88736.1 - 0.14 11.8 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MULE PF10551.9 EAX88737.1 - 1.8e-10 41.1 0.1 4.9e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain HTH_Tnp_1_2 PF13022.6 EAX88737.1 - 0.027 14.6 3.5 0.073 13.2 0.2 2.9 2 1 1 3 3 3 0 Helix-turn-helix of insertion element transposase rve PF00665.26 EAX88738.1 - 3e-20 72.6 0.0 4.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX88738.1 - 9.4e-08 32.4 0.3 7.3e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.6 EAX88738.1 - 1.5e-05 24.7 0.7 0.00013 21.6 0.4 2.7 2 1 0 2 2 2 1 Integrase core domain Big_7 PF17957.1 EAX88739.1 - 4.8 8.0 10.8 1.3 9.9 0.2 3.9 4 1 1 5 5 5 0 Bacterial Ig domain Beach PF02138.18 EAX88740.1 - 1.4e-82 277.2 6.0 2.3e-82 276.5 6.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EAX88740.1 - 0.007 17.2 0.2 29 5.8 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Hpr_kinase_N PF02603.16 EAX88740.1 - 0.047 13.7 0.6 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase N terminus DUF4704 PF15787.5 EAX88741.1 - 0.00052 19.3 2.8 0.00096 18.5 2.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) Chibby PF14645.6 EAX88742.1 - 0.094 13.1 0.3 0.24 11.8 0.3 1.6 1 0 0 1 1 1 0 Chibby family DUF1540 PF07561.11 EAX88742.1 - 6.8 7.1 9.0 30 5.0 3.6 3.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1540) LRR_5 PF13306.6 EAX88743.1 - 7.8e-134 439.7 90.2 4.4e-35 120.4 14.2 5.3 2 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88743.1 - 1.4e-16 60.0 5.3 0.071 12.9 0.1 8.2 7 3 1 9 9 9 5 Leucine rich repeat DUF3557 PF12078.8 EAX88743.1 - 0.11 12.4 1.3 0.48 10.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3557) GvpK PF05121.12 EAX88744.1 - 0.19 11.8 3.6 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K Antimicrobial_7 PF08102.11 EAX88745.1 - 0.069 13.4 1.6 0.13 12.5 1.3 1.8 1 1 0 1 1 1 0 Scorpion antimicrobial peptide Spo12 PF05032.12 EAX88746.1 - 0.39 10.7 6.4 0.16 11.9 2.9 2.1 3 0 0 3 3 3 0 Spo12 family Histone PF00125.24 EAX88748.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX88748.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX88748.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX88748.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Histone PF00125.24 EAX88749.1 - 2.1e-17 63.7 0.0 2.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX88749.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX88749.1 - 0.0025 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 EAX88749.1 - 0.058 13.1 0.2 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 EAX88749.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 LcrG protein AphA_like PF14557.6 EAX88750.1 - 0.0082 15.9 3.3 0.011 15.5 1.2 2.4 2 0 0 2 2 2 1 Putative AphA-like transcriptional regulator JAB PF01398.21 EAX88751.1 - 0.0034 17.3 0.0 0.0099 15.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Amidase02_C PF12123.8 EAX88753.1 - 0.074 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88754.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX88754.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF5365 PF17326.2 EAX88755.1 - 0.03 14.7 0.1 0.055 13.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5365) MULE PF10551.9 EAX88756.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX88756.1 - 0.049 13.8 3.2 0.089 12.9 3.2 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain Metallophos PF00149.28 EAX88757.1 - 4.9e-29 102.3 0.2 6.3e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PMT PF02366.18 EAX88758.1 - 2.8e-42 145.0 13.9 2.8e-42 145.0 13.9 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX88758.1 - 5.5e-22 78.3 22.0 5.5e-22 78.3 22.0 2.2 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase Glyco_transf_17 PF04724.13 EAX88759.1 - 5.9e-14 51.9 0.1 7.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Pkinase PF00069.25 EAX88760.1 - 5.7e-46 157.0 0.0 7.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88760.1 - 7e-29 100.9 0.0 8.8e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88760.1 - 0.001 18.5 0.0 0.0053 16.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF4973 PF16343.5 EAX88760.1 - 0.032 14.3 1.1 0.054 13.5 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) Gly-zipper_Omp PF13488.6 EAX88762.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper Zincin_2 PF10103.9 EAX88762.1 - 0.18 11.1 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX88762.1 - 0.22 11.8 4.9 0.39 11.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX88762.1 - 1.4 9.1 6.5 2.3 8.4 6.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX88764.1 - 4.3e-05 23.1 3.8 7.6e-05 22.3 3.8 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX88764.1 - 0.0037 17.3 1.2 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX88764.1 - 0.0099 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX88764.1 - 0.05 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX88764.1 - 0.075 13.3 2.2 0.15 12.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PARP PF00644.20 EAX88766.1 - 4.8e-14 52.4 0.3 1.1e-13 51.2 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EAX88766.1 - 0.0069 16.6 0.1 0.72 10.1 0.0 3.4 2 1 1 3 3 3 1 ARTD15 N-terminal domain zf-P11 PF03854.14 EAX88766.1 - 2.2 8.0 9.0 0.36 10.5 2.8 2.4 2 0 0 2 2 2 0 P-11 zinc finger DUF3108 PF11306.8 EAX88768.1 - 0.044 13.8 0.4 0.09 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Kinesin_assoc PF16183.5 EAX88768.1 - 3.1 7.9 12.1 2 8.5 5.4 2.3 2 0 0 2 2 2 0 Kinesin-associated VraX PF17412.2 EAX88769.1 - 0.084 12.5 0.1 0.37 10.5 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function Helicase_C PF00271.31 EAX88770.1 - 1.8e-23 83.0 1.9 2e-23 82.9 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAX88770.1 - 8e-23 81.1 0.0 6.5e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX88770.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.20 EAX88771.1 - 2.6e-112 376.1 12.5 3.3e-112 375.7 12.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX88771.1 - 8.7e-43 146.2 0.6 8.7e-43 146.2 0.6 3.5 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAX88771.1 - 5e-19 68.5 0.2 2.4e-06 27.8 0.0 5.8 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 EAX88771.1 - 1.4e-14 52.9 1.3 0.012 15.8 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.8 EAX88771.1 - 1.4e-07 31.3 2.2 0.021 14.4 0.1 4.0 3 1 1 4 4 4 3 CLASP N terminal Arm PF00514.23 EAX88771.1 - 2.7e-07 30.4 0.3 0.16 12.0 0.0 6.0 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAX88771.1 - 4.8e-06 27.0 0.4 0.09 13.3 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 EAX88771.1 - 9.2e-06 25.1 2.6 0.0044 16.3 0.1 3.1 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.7 EAX88771.1 - 0.001 19.0 1.9 0.46 10.4 0.1 3.5 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EAX88771.1 - 0.0059 16.8 0.4 4.4 7.5 0.1 3.5 2 2 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EAX88771.1 - 0.22 12.1 4.2 0.49 11.0 0.1 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Sugar_tr PF00083.24 EAX88772.1 - 1.1e-51 176.2 28.1 2.3e-32 112.4 9.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX88772.1 - 2.3e-20 72.9 28.2 2.3e-20 72.9 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EAX88772.1 - 0.012 16.1 0.8 0.012 16.1 0.8 2.2 2 0 0 2 2 2 0 Phage holin family 2 BTP PF05232.12 EAX88772.1 - 0.87 9.7 8.4 0.12 12.4 1.1 2.9 2 0 0 2 2 2 0 Chlorhexidine efflux transporter Ras PF00071.22 EAX88773.1 - 2.3e-05 24.1 0.0 2.5e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88773.1 - 0.023 14.9 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase YbgT_YccB PF08173.11 EAX88774.1 - 8.4 6.6 6.9 1.8 8.7 3.4 1.8 2 0 0 2 2 2 0 Membrane bound YbgT-like protein DUF3839 PF12943.7 EAX88775.1 - 6.1e-153 507.2 15.4 7.5e-153 506.9 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88775.1 - 0.047 14.1 1.8 0.19 12.1 0.3 2.1 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX88775.1 - 0.21 11.9 5.8 0.57 10.5 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX88775.1 - 0.24 11.3 2.1 0.55 10.1 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX88775.1 - 0.86 10.1 6.0 5.2 7.6 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX88775.1 - 1.6 9.3 5.5 0.88 10.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PSP PF04046.16 EAX88776.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX88778.1 - 9.7e-29 99.1 0.6 9.7e-29 99.1 0.6 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88778.1 - 0.018 15.6 0.2 0.38 11.4 0.2 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF1512 PF07431.12 EAX88778.1 - 0.14 11.1 0.7 0.24 10.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Ank_2 PF12796.7 EAX88779.1 - 6.8e-49 164.4 29.3 5e-16 59.1 4.6 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88779.1 - 1.5e-48 162.5 9.8 7.9e-11 42.3 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88779.1 - 9.7e-42 139.6 12.5 4e-06 27.0 0.2 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX88779.1 - 4.5e-35 115.7 5.7 2.5e-05 24.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX88779.1 - 2.9e-28 97.5 5.3 2.8e-09 37.1 0.3 4.1 4 0 0 4 4 4 4 Ankyrin repeats (many copies) DUF5064 PF16703.5 EAX88779.1 - 0.004 17.6 0.4 0.87 10.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5064) ATPase PF06745.13 EAX88779.1 - 0.0079 15.6 1.1 0.99 8.7 0.1 2.1 1 1 1 2 2 2 2 KaiC DUF3718 PF12514.8 EAX88779.1 - 0.011 15.8 4.4 7.8 6.7 0.1 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF3718) PrmC_N PF17827.1 EAX88779.1 - 0.028 15.0 0.4 26 5.5 0.0 3.8 3 1 1 4 4 4 0 PrmC N-terminal domain Prion PF00377.18 EAX88779.1 - 0.054 13.3 2.9 12 5.7 0.6 3.6 1 1 3 4 4 4 0 Prion/Doppel alpha-helical domain Stap_Strp_toxin PF01123.20 EAX88779.1 - 0.059 14.2 4.2 3.9 8.4 0.3 3.1 2 2 2 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain Ribosomal_S6 PF01250.17 EAX88779.1 - 0.44 10.9 2.5 4.3 7.7 0.1 3.0 1 1 1 4 4 4 0 Ribosomal protein S6 SCVP PF17619.2 EAX88779.1 - 4.2 8.3 7.7 10 7.1 0.8 3.3 1 1 3 4 4 4 0 Secreted clade V proteins PRIMA1 PF16101.5 EAX88780.1 - 2.7e-05 24.2 0.1 5.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF1180 PF06679.12 EAX88780.1 - 0.00011 22.7 0.3 0.00021 21.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Cadherin_C_2 PF16492.5 EAX88780.1 - 0.00016 22.3 0.2 0.0011 19.7 0.4 2.3 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Shisa PF13908.6 EAX88780.1 - 0.0035 17.6 2.3 0.0035 17.6 2.3 2.0 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EAX88780.1 - 0.0084 16.4 1.3 0.0084 16.4 1.3 3.2 3 1 1 4 4 4 1 Orf78 (ac78) TMEM154 PF15102.6 EAX88780.1 - 0.012 15.5 2.1 0.012 15.5 2.1 3.3 3 1 1 4 4 4 0 TMEM154 protein family Vpu PF00558.19 EAX88780.1 - 0.024 14.4 0.3 0.052 13.3 0.3 1.5 1 0 0 1 1 1 0 Vpu protein LRR19-TM PF15176.6 EAX88780.1 - 0.024 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain RIFIN PF02009.16 EAX88780.1 - 0.047 13.6 0.7 0.086 12.7 0.1 1.8 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 EAX88780.1 - 0.058 14.3 1.4 0.082 13.8 0.3 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 EAX88780.1 - 0.069 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 SCIMP protein Invas_SpaK PF03519.14 EAX88780.1 - 0.077 13.1 0.3 2.8 8.1 0.0 3.3 3 0 0 3 3 3 0 Invasion protein B family Gemini_mov PF01708.16 EAX88780.1 - 0.13 12.0 0.3 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Geminivirus putative movement protein RSS_P20 PF11757.8 EAX88781.1 - 0.02 15.3 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain RNA_pol_Rbc25 PF08292.12 EAX88783.1 - 3.2e-18 66.2 4.6 1.4e-14 54.4 0.3 2.2 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EAX88783.1 - 2.4e-15 56.7 0.1 4.2e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF2070 PF09843.9 EAX88784.1 - 0.013 13.8 8.2 0.017 13.5 8.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 EAX88784.1 - 7.6 5.2 9.9 87 1.7 9.9 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Gly_rich PF12810.7 EAX88786.1 - 2.1e-26 93.3 15.7 2.4e-26 93.1 15.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Actin PF00022.19 EAX88787.1 - 5.5e-139 463.3 0.0 2.1e-138 461.4 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX88787.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Tubulin_C PF03953.17 EAX88788.1 - 3e-39 134.0 0.0 5e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L15e PF00827.17 EAX88789.1 - 7.6e-81 270.4 0.8 8.6e-81 270.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 HAND PF09110.11 EAX88790.1 - 0.014 16.1 8.0 0.019 15.7 8.0 1.1 1 0 0 1 1 1 0 HAND Serinc PF03348.15 EAX88790.1 - 0.19 10.6 1.7 0.21 10.5 1.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 EAX88790.1 - 0.69 9.6 4.4 0.85 9.3 4.4 1.1 1 0 0 1 1 1 0 Connexin Ank_2 PF12796.7 EAX88791.1 - 5.5e-47 158.3 22.8 1.7e-15 57.4 1.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88791.1 - 2.8e-41 139.3 7.0 3.7e-11 43.3 0.0 7.7 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX88791.1 - 1.4e-37 126.5 6.2 3e-07 30.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAX88791.1 - 2.3e-34 113.5 10.9 2.2e-05 24.5 0.0 9.5 8 1 2 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX88791.1 - 3.4e-34 116.6 5.3 3.4e-34 116.6 5.3 3.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX88791.1 - 2.5e-29 100.9 9.2 7.9e-09 35.6 0.0 6.0 2 2 5 7 7 7 6 Ankyrin repeats (many copies) YcxB PF14317.6 EAX88791.1 - 0.0032 17.1 0.1 13 5.6 0.0 3.8 1 1 2 3 3 3 2 YcxB-like protein DUF3718 PF12514.8 EAX88791.1 - 0.15 12.2 0.4 51 4.1 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3718) AAA_14 PF13173.6 EAX88792.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX88792.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PTR PF12789.7 EAX88793.1 - 8.7e-23 80.2 20.6 2e-16 59.7 2.0 4.5 6 0 0 6 6 6 2 Phage tail repeat like Peptidase_C78 PF07910.13 EAX88793.1 - 0.062 12.8 0.4 5.5 6.4 0.0 2.5 1 1 1 2 2 2 0 Peptidase family C78 DUF240 PF03086.14 EAX88793.1 - 0.078 12.9 4.3 1.5 8.8 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF4116 PF13475.6 EAX88793.1 - 0.089 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX88793.1 - 4.7 7.8 18.8 0.96 10.0 0.3 4.2 2 2 0 3 3 3 0 YmaF family DUF1493 PF07377.12 EAX88794.1 - 0.028 14.9 0.8 0.061 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX88795.1 - 0.069 13.7 4.7 11 7.2 0.2 3.2 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88796.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TPR_1 PF00515.28 EAX88797.1 - 2.6e-10 39.7 0.2 0.0023 17.7 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX88797.1 - 3.3e-10 39.3 0.2 0.00023 21.1 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX88797.1 - 1.3e-08 34.3 5.1 0.0014 18.2 0.1 3.1 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 EAX88797.1 - 0.00022 21.8 0.0 0.036 14.9 0.0 3.3 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX88797.1 - 0.013 15.8 1.4 9 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAX88797.1 - 0.014 16.0 0.0 9.4 7.0 0.0 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAX88797.1 - 0.027 14.6 0.0 0.7 10.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat ALMT PF11744.8 EAX88797.1 - 0.051 12.4 5.0 0.062 12.1 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TPR_6 PF13174.6 EAX88797.1 - 0.063 13.9 0.2 0.27 11.9 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma70_r3 PF04539.16 EAX88797.1 - 0.12 12.5 2.0 7.8 6.7 0.2 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 TPR_8 PF13181.6 EAX88797.1 - 0.14 12.4 0.5 1.8 9.0 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Focal_AT PF03623.13 EAX88797.1 - 0.67 9.9 4.0 0.21 11.6 0.7 1.7 2 0 0 2 2 2 0 Focal adhesion targeting region IKKbetaNEMObind PF12179.8 EAX88797.1 - 2.3 8.3 6.2 0.59 10.2 0.8 2.5 2 1 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain TPH PF13868.6 EAX88798.1 - 2.7e-14 52.5 122.4 2.7e-14 52.5 122.4 2.5 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain Ank_2 PF12796.7 EAX88799.1 - 1.1e-31 109.2 24.0 6.4e-14 52.3 1.5 6.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88799.1 - 1.7e-28 98.6 17.2 4.9e-08 33.4 0.1 8.0 5 2 5 10 10 10 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX88799.1 - 2.9e-28 97.6 3.1 2.9e-28 97.6 3.1 6.3 4 1 3 8 8 8 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX88799.1 - 3.8e-25 87.2 6.2 4.6e-06 26.8 0.1 8.1 8 2 1 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 EAX88799.1 - 5.7e-25 84.7 12.5 0.0012 19.2 0.1 11.0 12 1 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 EAX88799.1 - 6.1e-25 87.0 1.3 1.6e-08 34.7 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) RL PF17797.1 EAX88799.1 - 0.0013 18.6 0.6 1 9.3 0.1 3.7 4 0 0 4 4 4 1 RL domain PH_8 PF15409.6 EAX88799.1 - 0.027 14.7 0.1 1.9 8.8 0.0 3.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4108 PF13390.6 EAX88801.1 - 1.4e-61 206.6 8.4 1.6e-61 206.5 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ras PF00071.22 EAX88803.1 - 8.1e-35 119.8 0.0 9.5e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88803.1 - 8.5e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EAX88803.1 - 9.2e-05 22.4 1.4 0.4 10.6 0.2 2.6 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX88803.1 - 0.00031 20.2 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88803.1 - 0.00044 20.3 0.0 0.00058 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX88803.1 - 0.0025 18.1 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EAX88803.1 - 0.0031 17.0 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EAX88803.1 - 0.0032 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 EAX88803.1 - 0.0044 16.6 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Arf PF00025.21 EAX88803.1 - 0.0051 16.3 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 EAX88803.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EAX88803.1 - 0.012 15.1 0.0 0.23 11.0 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EAX88803.1 - 0.018 14.8 1.7 0.47 10.2 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EAX88803.1 - 0.029 14.1 0.2 0.22 11.3 0.1 2.1 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAX88803.1 - 0.029 14.1 0.1 0.24 11.1 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX88803.1 - 0.051 13.9 0.0 0.065 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AnfG_VnfG PF03139.15 EAX88804.1 - 0.11 12.7 0.1 7.5 6.7 0.0 2.1 1 1 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Sin3_corepress PF08295.12 EAX88805.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor UCH PF00443.29 EAX88806.1 - 1.9e-28 99.7 0.1 4.5e-28 98.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX88806.1 - 4.2e-07 29.9 0.3 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase VPS11_C PF12451.8 EAX88806.1 - 0.14 12.4 0.0 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Vps26 PF03643.15 EAX88807.1 - 2.4e-33 115.3 0.1 3.2e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 EAX88807.1 - 0.011 16.2 0.5 0.97 9.9 0.0 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Profilin PF00235.19 EAX88808.1 - 1.2e-06 28.8 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Profilin RecC_C PF17946.1 EAX88809.1 - 0.1 12.4 0.9 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 RecC C-terminal domain EF-hand_14 PF17959.1 EAX88809.1 - 0.1 12.9 4.2 0.13 12.6 3.5 1.6 1 1 1 2 2 2 0 EF-hand domain Turandot PF07240.11 EAX88809.1 - 0.31 11.0 6.2 0.067 13.2 1.9 1.9 1 1 1 2 2 2 0 Stress-inducible humoral factor Turandot Med21 PF11221.8 EAX88809.1 - 1.9 8.7 11.9 4.6 7.5 1.9 2.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF3839 PF12943.7 EAX88810.1 - 8.6e-120 398.6 6.5 9.8e-120 398.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX88811.1 - 2e-17 63.0 0.0 4.2e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Ank_4 PF13637.6 EAX88813.1 - 1.3e-08 35.2 1.6 3.7e-05 24.2 0.3 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX88813.1 - 2.3e-08 34.1 0.3 4.5e-07 30.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX88813.1 - 2.6e-06 27.9 0.1 6.6e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88813.1 - 0.0002 21.6 4.3 0.00084 19.6 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EAX88813.1 - 0.0038 17.6 1.6 0.014 15.8 0.1 2.9 3 1 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 EAX88813.1 - 0.012 15.6 3.1 0.05 13.6 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) EF-hand_1 PF00036.32 EAX88814.1 - 1e-30 102.9 12.5 4e-07 29.1 1.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX88814.1 - 7.3e-27 93.6 6.5 1.6e-14 54.1 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX88814.1 - 4.1e-24 82.4 12.3 5.3e-08 32.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX88814.1 - 1.1e-21 76.5 10.1 2.8e-11 43.1 0.2 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX88814.1 - 1.4e-15 56.0 11.8 8.6e-05 21.9 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX88814.1 - 3.4e-09 36.9 0.2 0.00021 21.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX88814.1 - 4.7e-08 33.3 0.2 0.00057 20.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAX88814.1 - 4.2e-07 29.9 0.7 0.012 15.6 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EAX88814.1 - 0.00016 21.8 4.3 0.14 12.4 0.2 2.8 2 2 1 3 3 3 2 Dockerin type I domain TerB PF05099.13 EAX88814.1 - 0.0011 19.0 0.1 0.037 14.0 0.3 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 EAX88814.1 - 0.0026 17.7 3.5 1.5 8.7 0.1 3.6 1 1 3 4 4 4 2 Caleosin related protein DUF3349 PF11829.8 EAX88814.1 - 0.014 16.1 0.0 0.44 11.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) DUF5580 PF17743.1 EAX88814.1 - 0.05 12.1 0.0 0.13 10.7 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5580) EF-hand_13 PF17958.1 EAX88814.1 - 0.057 13.2 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain PMT PF02366.18 EAX88815.1 - 2.6e-35 122.2 10.6 2.6e-35 122.2 10.6 1.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX88815.1 - 2.3e-19 69.8 12.6 2.3e-19 69.8 12.6 3.0 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase START PF01852.19 EAX88816.1 - 7.3e-09 35.3 0.0 1.1e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 START domain Ank_2 PF12796.7 EAX88819.1 - 8.1e-56 186.6 34.5 5.4e-15 55.7 1.4 6.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88819.1 - 5.4e-53 176.7 21.4 1.6e-10 41.3 0.2 9.7 4 1 6 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX88819.1 - 3.2e-40 134.8 16.3 6e-07 29.6 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 EAX88819.1 - 4.4e-39 132.3 5.6 4.4e-39 132.3 5.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX88819.1 - 1.1e-33 114.8 22.3 1.6e-10 41.0 0.3 6.2 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88819.1 - 1.3e-32 108.1 19.1 4e-06 26.8 0.1 9.3 9 1 1 10 10 10 5 Ankyrin repeat DUF3718 PF12514.8 EAX88819.1 - 0.004 17.3 1.9 37 4.6 0.0 5.7 5 1 1 6 6 6 0 Protein of unknown function (DUF3718) IlvN PF07991.12 EAX88819.1 - 0.064 12.8 0.5 8.9 5.9 0.1 3.8 1 1 3 4 4 4 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ntox33 PF15533.6 EAX88819.1 - 0.28 11.7 7.9 21 5.7 0.1 5.0 3 1 3 6 6 6 0 Bacterial toxin 33 KilA-N PF04383.13 EAX88820.1 - 7.2e-14 51.6 0.1 9.6e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX88821.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pkinase PF00069.25 EAX88822.1 - 1e-42 146.4 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88822.1 - 2.5e-22 79.4 0.0 1.5e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX88822.1 - 0.00013 22.0 0.2 0.0013 18.7 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX88822.1 - 0.00074 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX88822.1 - 0.0015 18.2 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family ELFV_dehydrog PF00208.21 EAX88823.1 - 1.8e-80 270.2 0.1 2.2e-80 269.9 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EAX88823.1 - 9.9e-50 167.8 0.0 3.7e-49 165.9 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 EAX88823.1 - 0.035 14.2 0.2 0.1 12.7 0.3 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.19 EAX88823.1 - 0.11 11.1 0.1 0.9 8.2 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Ank_2 PF12796.7 EAX88824.1 - 6.1e-35 119.7 15.0 4.7e-15 55.9 0.9 4.8 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88824.1 - 4.8e-31 106.7 6.4 6.7e-13 48.9 0.1 7.4 3 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX88824.1 - 3.9e-29 99.8 7.0 1.9e-06 28.1 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX88824.1 - 1.2e-28 98.7 4.2 2.8e-11 43.4 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88824.1 - 3e-28 94.7 9.5 2.5e-05 24.3 0.1 8.4 8 1 1 9 9 9 4 Ankyrin repeat DUF3447 PF11929.8 EAX88824.1 - 1e-26 92.7 8.3 1e-26 92.7 8.3 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DHBP_synthase PF00926.19 EAX88824.1 - 0.11 12.0 0.0 3.4 7.2 0.0 3.0 2 1 1 3 3 3 0 3,4-dihydroxy-2-butanone 4-phosphate synthase MMS19_C PF12460.8 EAX88825.1 - 0.019 14.1 1.7 0.036 13.2 1.7 1.5 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal DUF2922 PF11148.8 EAX88825.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Pox_EPC_I2-L1 PF12575.8 EAX88826.1 - 0.0017 18.5 1.0 1.6 9.0 0.0 3.2 3 0 0 3 3 3 2 Poxvirus entry protein complex L1 and I2 Peptidase_M18 PF02127.15 EAX88828.1 - 2.6e-64 217.6 0.1 1.1e-35 123.3 0.0 2.3 2 1 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Ank_2 PF12796.7 EAX88829.1 - 6.2e-33 113.2 5.1 1e-16 61.3 0.3 3.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88829.1 - 1.9e-21 75.9 2.1 1e-14 54.4 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88829.1 - 3.9e-18 63.7 2.2 3.3e-06 27.0 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EAX88829.1 - 5.4e-18 65.1 1.1 7.9e-07 29.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX88829.1 - 4.5e-13 49.0 1.6 3.5e-05 24.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF3718 PF12514.8 EAX88829.1 - 0.0085 16.2 0.1 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3718) MIF4G PF02854.19 EAX88829.1 - 0.017 14.8 4.2 0.034 13.8 4.2 1.5 1 1 0 1 1 1 0 MIF4G domain ELFV_dehydrog PF00208.21 EAX88830.1 - 1.8e-80 270.2 0.1 2.2e-80 269.9 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EAX88830.1 - 9.9e-50 167.8 0.0 3.7e-49 165.9 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 EAX88830.1 - 0.035 14.2 0.2 0.1 12.7 0.3 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.19 EAX88830.1 - 0.11 11.1 0.1 0.9 8.2 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Meiosis_expr PF15163.6 EAX88833.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX88833.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX88833.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family DUF3839 PF12943.7 EAX88834.1 - 3.8e-154 511.1 12.3 4.7e-154 510.8 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX88834.1 - 0.0094 15.2 0.0 0.17 11.1 0.0 2.0 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Fez1 PF06818.15 EAX88834.1 - 0.056 13.9 1.6 0.21 12.0 0.3 2.0 2 0 0 2 2 2 0 Fez1 Glu-tRNAGln PF02686.15 EAX88834.1 - 0.1 12.9 0.6 0.68 10.3 0.2 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX88834.1 - 0.44 11.1 5.2 0.19 12.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX88834.1 - 0.83 10.2 4.5 5.1 7.6 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX88836.1 - 3.5e-06 26.6 0.0 4.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Amidase02_C PF12123.8 EAX88837.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX88838.1 - 5.2e-71 238.0 3.7 7.9e-71 237.5 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX88839.1 - 3.3e-06 26.8 0.1 4.2e-06 26.4 0.1 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX88840.1 - 5e-12 45.7 0.1 5.2e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX88841.1 - 1.7e-146 486.1 8.1 2.1e-146 485.8 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX88841.1 - 0.014 15.8 3.9 0.22 12.0 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PA28_beta PF02252.18 EAX88841.1 - 0.019 14.7 0.9 0.062 13.0 0.3 2.2 1 1 0 2 2 2 0 Proteasome activator pa28 beta subunit Ccdc124 PF06244.12 EAX88841.1 - 0.21 12.1 1.6 0.27 11.8 1.6 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 ANAPC4_WD40 PF12894.7 EAX88842.1 - 3.9e-05 23.9 0.0 0.022 15.1 0.0 4.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 EAX88842.1 - 0.0029 16.4 0.5 3.1 6.4 0.0 3.0 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal SRP14 PF02290.15 EAX88842.1 - 0.021 15.2 0.3 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle 14kD protein La PF05383.17 EAX88843.1 - 1.3e-12 47.6 0.3 3e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 La domain Myb_DNA-binding PF00249.31 EAX88844.1 - 2.2e-23 82.2 0.1 2.3e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88844.1 - 4.8e-18 65.2 0.5 2.7e-09 37.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX88844.1 - 4.7e-05 23.5 0.1 0.76 10.0 0.0 3.3 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX88844.1 - 0.00046 20.0 0.1 0.0035 17.2 0.0 2.4 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX88844.1 - 0.011 15.8 0.9 5 7.2 0.0 3.2 1 1 2 3 3 3 0 SLIDE SANT_DAMP1_like PF16282.5 EAX88844.1 - 0.03 14.5 0.0 0.12 12.6 0.0 1.9 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 FCH PF00611.23 EAX88844.1 - 0.13 12.6 0.6 0.26 11.6 0.6 1.6 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF5038 PF16441.5 EAX88844.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) Bromodomain PF00439.25 EAX88845.1 - 5.3e-07 29.6 0.2 1.2e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain LPD38 PF18857.1 EAX88845.1 - 0.023 14.8 0.2 0.037 14.2 0.2 1.3 1 1 0 1 1 1 0 Large polyvalent protein associated domain 38 Pkinase PF00069.25 EAX88846.1 - 5.5e-57 193.1 0.2 7e-57 192.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88846.1 - 4.4e-32 111.4 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88846.1 - 4.4e-08 32.8 0.0 8.8e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RE_AccI PF09545.10 EAX88846.1 - 0.035 13.1 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease Forkhead PF00250.18 EAX88846.1 - 0.091 13.0 0.2 0.28 11.5 0.2 1.8 1 0 0 1 1 1 0 Forkhead domain ABC_membrane PF00664.23 EAX88847.1 - 2.1e-21 76.8 14.2 2.6e-21 76.5 14.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4257 PF14074.6 EAX88847.1 - 1.2 9.4 7.6 0.28 11.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) ABC_tran PF00005.27 EAX88848.1 - 1.3e-31 110.0 0.0 2.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX88848.1 - 3e-08 33.4 0.8 3.9e-07 29.7 0.2 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAX88848.1 - 0.00011 22.5 0.1 0.00044 20.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EAX88848.1 - 0.00014 21.8 0.0 0.12 12.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 EAX88848.1 - 0.00094 18.9 0.1 0.0013 18.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EAX88848.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EAX88848.1 - 0.0037 17.7 0.6 0.0098 16.3 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX88848.1 - 0.0084 16.0 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EAX88848.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EAX88848.1 - 0.03 14.1 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX88848.1 - 0.037 14.5 0.2 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAX88848.1 - 0.1 12.3 0.3 0.25 11.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX88848.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAX88848.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 EAX88848.1 - 0.14 12.2 0.2 1 9.4 0.1 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF563 PF04577.14 EAX88850.1 - 1.7e-35 123.1 0.1 2.9e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF4108 PF13390.6 EAX88851.1 - 9.7e-60 200.6 8.7 1.1e-59 200.5 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX88851.1 - 0.11 12.7 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3464 PF11947.8 EAX88852.1 - 0.8 9.4 2.4 1.3 8.7 2.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA_11 PF13086.6 EAX88853.1 - 0.025 14.4 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX88853.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX88853.1 - 0.18 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.13 EAX88854.1 - 1.6e-41 140.6 1.3 2.5e-41 140.1 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX88854.1 - 0.01 16.5 0.1 0.043 14.4 0.0 2.1 2 0 0 2 2 2 0 Parathyroid hormone family Ank_2 PF12796.7 EAX88855.1 - 3.2e-27 94.9 0.0 6.5e-13 49.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88855.1 - 1.1e-22 79.4 0.0 6.5e-06 26.4 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX88855.1 - 1.5e-20 73.0 0.0 7.2e-08 32.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88855.1 - 4.4e-19 68.6 0.0 3.4e-10 40.2 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88855.1 - 2.7e-17 61.1 0.0 0.0059 17.0 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat L_protein_N PF15518.6 EAX88855.1 - 0.0015 18.3 2.4 0.39 10.6 0.0 4.3 4 1 1 5 5 5 1 L protein N-terminus TetR_C_19 PF17924.1 EAX88855.1 - 6.5 7.4 13.9 2.1 8.9 6.6 2.7 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SGS PF05002.15 EAX88856.1 - 0.00064 19.8 5.4 0.0012 18.9 5.4 1.5 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 EAX88856.1 - 0.0061 16.8 3.3 0.017 15.4 0.0 3.0 2 1 1 3 3 3 1 Siah interacting protein, N terminal Chorein_N PF12624.7 EAX88858.1 - 6.7e-05 23.0 7.1 0.00011 22.3 0.0 4.3 4 1 1 5 5 5 1 N-terminal region of Chorein or VPS13 zf-CCHC_3 PF13917.6 EAX88858.1 - 0.24 11.4 1.2 18 5.4 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle ARA70 PF12489.8 EAX88859.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pkinase PF00069.25 EAX88860.1 - 2.6e-48 164.7 3.3 1.6e-35 122.7 0.3 3.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88860.1 - 3.1e-34 118.4 5.7 6.3e-27 94.5 0.1 3.8 3 1 1 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 EAX88860.1 - 1.6e-05 24.4 0.0 4.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX88860.1 - 0.015 14.6 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX88860.1 - 0.029 14.0 1.4 0.42 10.2 0.1 3.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX88860.1 - 0.17 11.8 0.1 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RWD PF05773.22 EAX88860.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.7 3 1 0 3 3 3 0 RWD domain Thioredoxin PF00085.20 EAX88861.1 - 1.6e-20 73.0 0.0 1.7e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX88861.1 - 3.6e-07 30.4 0.1 4.9e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX88861.1 - 1.4e-06 28.7 0.1 1e-05 25.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EAX88861.1 - 0.00048 20.0 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EAX88861.1 - 0.0015 18.0 0.1 0.0015 18.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EAX88861.1 - 0.0024 18.0 0.2 0.0046 17.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EAX88861.1 - 0.0054 16.9 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DIM1 PF02966.16 EAX88861.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Redoxin PF08534.10 EAX88861.1 - 0.03 14.0 0.1 0.054 13.2 0.1 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EAX88861.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 EAX88861.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Sulfotransfer_4 PF17784.1 EAX88861.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain WRKY PF03106.15 EAX88862.1 - 0.05 13.8 1.0 0.05 13.8 1.0 2.8 2 2 1 3 3 3 0 WRKY DNA -binding domain DUF2846 PF11008.8 EAX88863.1 - 0.0077 16.2 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) PSP PF04046.16 EAX88864.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88865.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX88867.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88868.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX88869.1 - 1.6e-14 53.9 0.0 1.9e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88869.1 - 2.6e-09 36.7 0.0 3.2e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88869.1 - 0.0079 15.5 0.0 0.0099 15.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DENN PF02141.21 EAX88870.1 - 2.1e-14 53.9 1.7 7.5e-12 45.6 0.6 2.3 2 0 0 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 EAX88870.1 - 0.033 14.2 2.8 0.096 12.7 2.8 1.8 1 0 0 1 1 1 0 dDENN domain Pkinase PF00069.25 EAX88872.1 - 3.9e-57 193.6 0.1 4.5e-57 193.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88872.1 - 5.1e-31 107.9 0.1 2.9e-30 105.4 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX88872.1 - 7.8e-05 21.8 0.1 0.00011 21.3 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX88872.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX88872.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EAX88872.1 - 0.001 18.1 0.6 0.0015 17.6 0.6 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EAX88872.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX88872.1 - 0.037 12.8 0.1 0.057 12.2 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Myb_DNA-binding PF00249.31 EAX88873.1 - 7.1e-27 93.4 1.9 2.4e-12 46.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88873.1 - 2.3e-22 79.0 7.7 3.1e-14 52.9 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX88873.1 - 4.5e-06 26.5 4.8 0.00057 19.7 3.2 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX88873.1 - 0.06 13.5 2.1 0.075 13.2 1.1 1.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX88873.1 - 0.072 13.5 7.9 0.21 12.0 0.0 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_M20 PF01546.28 EAX88874.1 - 3.4e-06 26.9 0.0 1.3e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAX88874.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EAX88874.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EAX88874.1 - 0.0093 15.0 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Myb_DNA-binding PF00249.31 EAX88875.1 - 2.3e-24 85.3 7.8 7.9e-14 51.6 0.5 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX88875.1 - 1.4e-17 63.7 8.1 1.2e-12 47.9 1.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX88875.1 - 1.2e-05 25.2 1.2 0.24 11.4 0.0 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX88875.1 - 0.0053 16.9 0.5 0.8 9.9 0.2 2.9 2 1 0 2 2 2 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX88875.1 - 0.0064 16.4 3.7 0.032 14.1 1.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX88875.1 - 0.0093 16.3 7.7 0.21 12.0 0.2 2.9 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX88875.1 - 0.011 16.1 4.5 0.021 15.1 0.2 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.10 EAX88875.1 - 0.2 11.7 1.9 0.31 11.1 1.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HEPN_RES_NTD1 PF18870.1 EAX88875.1 - 0.31 11.2 5.8 5.7 7.2 0.5 2.5 2 1 1 3 3 3 0 HEPN/RES N-terminal domain 1 ABC_tran PF00005.27 EAX88876.1 - 8.6e-37 126.7 3.4 4.1e-19 69.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EAX88876.1 - 2.2e-19 69.3 5.4 2.2e-19 69.3 5.4 3.7 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 EAX88876.1 - 1.8e-11 44.4 4.7 0.00031 20.7 0.9 4.3 4 1 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX88876.1 - 1.4e-10 41.0 7.7 0.0002 20.9 0.0 4.0 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAX88876.1 - 1.7e-07 30.8 0.2 0.00027 20.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EAX88876.1 - 5.7e-06 26.2 0.4 0.21 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EAX88876.1 - 1.5e-05 25.0 0.7 0.015 15.4 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EAX88876.1 - 3.6e-05 23.8 0.6 0.12 12.4 0.0 3.5 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EAX88876.1 - 4.1e-05 23.6 0.3 0.19 11.6 0.0 2.9 3 0 0 3 3 2 2 NACHT domain RsgA_GTPase PF03193.16 EAX88876.1 - 4.3e-05 23.5 2.9 0.045 13.6 0.0 3.1 2 2 1 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EAX88876.1 - 0.0001 22.6 4.0 0.34 11.2 0.1 4.1 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 EAX88876.1 - 0.00011 22.7 2.9 0.035 14.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain DAP3 PF10236.9 EAX88876.1 - 0.00024 20.4 0.7 0.18 10.9 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 EAX88876.1 - 0.00026 21.3 0.1 0.56 10.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EAX88876.1 - 0.00038 20.0 0.2 0.86 9.1 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_33 PF13671.6 EAX88876.1 - 0.00052 20.2 0.1 0.54 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EAX88876.1 - 0.00054 19.2 1.1 0.088 12.0 0.0 3.2 4 0 0 4 4 4 1 NB-ARC domain PduV-EutP PF10662.9 EAX88876.1 - 0.00064 19.5 1.5 0.98 9.2 0.3 3.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EAX88876.1 - 0.00067 19.9 0.0 0.11 12.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain Septin PF00735.18 EAX88876.1 - 0.0013 18.1 0.1 0.43 9.8 0.0 2.6 2 0 0 2 2 2 1 Septin DUF815 PF05673.13 EAX88876.1 - 0.0031 16.7 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arf PF00025.21 EAX88876.1 - 0.0039 16.7 3.3 0.73 9.3 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_15 PF13175.6 EAX88876.1 - 0.0039 17.0 4.4 0.0039 17.0 4.4 4.2 3 1 1 4 4 3 2 AAA ATPase domain AAA_16 PF13191.6 EAX88876.1 - 0.0058 17.0 0.5 5.7 7.3 0.0 3.1 4 0 0 4 4 2 0 AAA ATPase domain G-alpha PF00503.20 EAX88876.1 - 0.0058 15.8 3.1 0.17 11.0 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit Roc PF08477.13 EAX88876.1 - 0.0062 16.8 0.1 5.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EAX88876.1 - 0.0068 15.8 0.1 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 EAX88876.1 - 0.013 15.7 0.1 4.4 7.6 0.2 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EAX88876.1 - 0.014 15.1 0.1 5.3 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EAX88876.1 - 0.021 15.3 0.1 13 6.2 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EAX88876.1 - 0.024 14.3 0.1 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APC1_C PF18122.1 EAX88876.1 - 0.027 14.4 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain AAA_23 PF13476.6 EAX88876.1 - 0.033 14.7 0.8 0.033 14.7 0.8 5.0 4 1 1 5 5 5 0 AAA domain TsaE PF02367.17 EAX88876.1 - 0.042 13.9 0.0 8.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EAX88876.1 - 0.053 12.5 0.0 4.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EAX88876.1 - 0.063 13.2 0.1 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 EAX88876.1 - 0.069 13.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 EAX88876.1 - 0.073 13.1 0.5 14 5.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SPT16 PF08644.11 EAX88876.1 - 0.073 13.3 10.2 0.091 12.9 0.4 2.8 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) cobW PF02492.19 EAX88876.1 - 0.092 12.3 1.6 6.6 6.3 0.3 3.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EAX88876.1 - 0.11 12.1 0.1 12 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 EAX88876.1 - 0.12 12.0 0.7 5.1 6.7 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 EAX88876.1 - 0.13 11.7 4.0 1.1 8.7 0.0 2.9 4 0 0 4 4 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 EAX88876.1 - 0.24 11.3 7.7 1.1 9.1 0.0 3.6 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EAX88876.1 - 0.25 11.2 3.5 12 5.8 0.0 3.3 3 0 0 3 3 2 0 NTPase Dynamin_N PF00350.23 EAX88876.1 - 0.66 10.0 0.0 0.66 10.0 0.0 2.6 3 1 0 3 3 1 0 Dynamin family DUF87 PF01935.17 EAX88876.1 - 0.79 9.8 11.6 3.7 7.6 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_19 PF13245.6 EAX88876.1 - 0.96 9.8 3.8 30 4.9 0.1 3.3 3 1 0 3 3 2 0 AAA domain Pkinase PF00069.25 EAX88877.1 - 2.9e-57 194.0 0.0 3.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88877.1 - 5e-36 124.3 0.1 6.8e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88877.1 - 6.8e-07 28.9 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX88877.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 1.7 2 1 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EAX88877.1 - 0.00032 19.8 0.3 0.00032 19.8 0.3 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EAX88877.1 - 0.00037 19.9 0.1 0.0006 19.2 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX88877.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Casc1 PF12366.8 EAX88877.1 - 0.047 13.2 0.6 0.44 10.0 0.5 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 YrbL-PhoP_reg PF10707.9 EAX88877.1 - 0.22 11.0 1.2 0.98 8.9 0.1 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PH_9 PF15410.6 EAX88878.1 - 0.094 13.1 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain CAMSAP_CKK PF08683.11 EAX88879.1 - 1.6e-15 57.3 0.0 3.8e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated SOBP PF15279.6 EAX88879.1 - 0.9 10.1 49.4 2.4 8.7 18.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein TPT PF03151.16 EAX88880.1 - 4.3e-17 62.4 17.5 5.3e-17 62.1 17.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Clc-like PF07062.12 EAX88880.1 - 0.35 10.3 8.5 0.18 11.3 3.1 2.3 2 0 0 2 2 2 0 Clc-like DUF1980 PF09323.10 EAX88880.1 - 0.42 10.5 2.9 0.27 11.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2157 PF09925.9 EAX88880.1 - 0.75 9.6 5.7 0.27 11.0 0.7 2.6 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 EAX88880.1 - 4.9 6.8 6.7 23 4.6 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) IBD PF10416.9 EAX88881.1 - 1.6e-30 105.8 2.8 2.1e-30 105.4 2.8 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Ras PF00071.22 EAX88882.1 - 2.7e-52 176.7 0.1 3.1e-52 176.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88882.1 - 4.2e-37 127.0 0.1 6.9e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88882.1 - 3.2e-19 69.0 0.1 4e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX88882.1 - 4.4e-08 33.2 0.0 6.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX88882.1 - 7.6e-08 32.4 0.1 0.00059 19.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX88882.1 - 7.3e-07 28.9 0.2 0.00017 21.2 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX88882.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX88882.1 - 5.1e-06 26.0 0.1 6.3e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EAX88882.1 - 1.1e-05 25.3 0.5 0.0012 18.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EAX88882.1 - 0.00031 20.5 0.1 0.00099 18.9 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX88882.1 - 0.0034 17.8 0.0 0.0048 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX88882.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 EAX88882.1 - 0.0044 16.6 0.3 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAX88882.1 - 0.006 16.1 0.2 0.01 15.3 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 EAX88882.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EAX88882.1 - 0.015 15.8 0.0 0.018 15.6 0.0 1.3 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EAX88882.1 - 0.017 14.6 0.3 0.11 12.0 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 EAX88882.1 - 0.031 14.5 0.1 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain TIR_2 PF13676.6 EAX88882.1 - 0.056 14.0 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain NADH-UOR_E PF16514.5 EAX88882.1 - 0.062 13.6 0.1 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E Dynamin_N PF00350.23 EAX88882.1 - 0.063 13.3 0.2 0.22 11.6 0.2 2.1 1 1 0 1 1 1 0 Dynamin family Calreticulin PF00262.18 EAX88883.1 - 4e-82 276.0 8.3 4.5e-61 206.7 0.8 2.2 1 1 1 2 2 2 2 Calreticulin family Dehydrin PF00257.19 EAX88883.1 - 0.082 13.5 1.0 0.14 12.7 1.0 1.3 1 0 0 1 1 1 0 Dehydrin DUF3447 PF11929.8 EAX88884.1 - 8.4e-39 131.4 6.2 8.4e-39 131.4 6.2 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88884.1 - 2.2e-11 44.2 2.1 4.7e-07 30.3 0.8 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88884.1 - 2.4e-11 43.9 0.2 0.00079 19.9 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX88884.1 - 3.5e-09 36.7 0.0 0.00021 21.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX88884.1 - 5.3e-08 33.0 0.0 3.8e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88884.1 - 9.1e-08 31.8 0.9 0.0024 18.2 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeat SWIRM PF04433.17 EAX88885.1 - 2e-20 72.9 0.2 4.3e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 SWIRM domain TMEM174 PF15029.6 EAX88886.1 - 0.2 11.3 3.1 0.34 10.6 3.1 1.4 1 1 0 1 1 1 0 Transmembrane protein 174 Gly_rich PF12810.7 EAX88887.1 - 5.9e-48 163.9 48.1 8.1e-48 163.5 48.1 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX88888.1 - 4.7e-85 282.0 80.2 2.8e-19 69.3 19.4 6.3 2 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX88888.1 - 1.8e-13 50.0 8.6 0.0028 17.4 2.0 7.3 6 1 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAX88888.1 - 0.0012 19.2 13.7 3.5 8.2 1.3 7.0 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX88888.1 - 3.7 8.5 8.0 32 5.6 0.2 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat EMP70 PF02990.16 EAX88889.1 - 1.1e-07 30.9 0.1 2.6e-07 29.7 0.1 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 DUF1493 PF07377.12 EAX88890.1 - 0.028 14.9 0.4 0.059 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX88891.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88892.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX88894.1 - 8.2e-55 186.0 0.1 1.1e-54 185.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88894.1 - 6.5e-37 127.2 0.0 7.8e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88894.1 - 7.3e-09 35.4 0.0 1.9e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAX88894.1 - 0.0044 16.4 0.1 0.007 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX88894.1 - 0.16 11.9 0.0 1.5 8.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1910 PF08928.10 EAX88894.1 - 0.47 10.5 3.5 0.19 11.8 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Alpha-amylase PF00128.24 EAX88895.1 - 4.1e-44 151.5 2.2 6.1e-26 91.8 0.4 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain RRM_1 PF00076.22 EAX88896.1 - 5e-09 35.9 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX88896.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF3839 PF12943.7 EAX88899.1 - 1.2e-56 191.8 3.3 1.6e-56 191.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAX88903.1 - 5.8e-22 78.2 8.1 6.7e-21 74.7 7.1 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX88903.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2400 PF09674.10 EAX88904.1 - 0.052 13.5 0.4 0.078 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAX88904.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX88904.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX88905.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX88905.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX88905.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF1043 PF06295.12 EAX88907.1 - 0.051 13.6 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX88907.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX88908.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX88908.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX88908.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX88908.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GPS2_interact PF15784.5 EAX88909.1 - 0.026 15.0 0.4 0.03 14.7 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88909.1 - 0.051 12.6 0.1 0.051 12.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX88911.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Ras PF00071.22 EAX88915.1 - 3e-38 131.0 0.0 3.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88915.1 - 4.9e-20 71.9 0.0 7.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88915.1 - 9.9e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX88915.1 - 0.00044 19.7 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX88915.1 - 0.0074 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EAX88915.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX88915.1 - 0.024 14.2 0.4 0.068 12.7 0.0 1.8 2 1 1 3 3 3 0 P-loop containing dynein motor region DLIC PF05783.11 EAX88915.1 - 0.067 12.0 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ish1 PF10281.9 EAX88915.1 - 0.08 13.3 0.2 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SRPRB PF09439.10 EAX88915.1 - 0.087 12.3 0.2 0.13 11.6 0.0 1.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX88915.1 - 0.14 11.9 0.1 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 EAX88915.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Ribonuc_P_40 PF08584.11 EAX88916.1 - 0.071 12.4 0.0 0.35 10.1 0.0 2.0 2 1 1 3 3 3 0 Ribonuclease P 40kDa (Rpp40) subunit DUF508 PF04370.12 EAX88917.1 - 0.068 12.9 0.6 0.15 11.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) MscS_porin PF12795.7 EAX88918.1 - 0.016 14.8 0.3 0.019 14.5 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YlqD PF11068.8 EAX88918.1 - 0.054 13.9 0.0 0.14 12.5 0.0 1.6 1 1 1 2 2 2 0 YlqD protein DNA_repr_REX1B PF14966.6 EAX88918.1 - 0.11 13.2 0.7 7.5 7.3 0.0 2.1 1 1 1 2 2 2 0 DNA repair REX1-B Pkinase PF00069.25 EAX88919.1 - 5.3e-65 219.4 0.0 6.4e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88919.1 - 7.4e-41 140.1 0.0 9.2e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88919.1 - 0.0034 16.8 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EAX88919.1 - 0.032 14.9 4.5 0.077 13.7 4.5 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain HECT PF00632.25 EAX88920.1 - 4.6e-56 190.6 0.0 9.6e-56 189.5 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3447 PF11929.8 EAX88921.1 - 0.0005 20.0 0.2 0.0005 20.0 0.2 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88921.1 - 0.004 17.7 0.1 0.51 11.0 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX88921.1 - 0.04 14.5 0.2 21 6.1 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat TF_Otx PF03529.13 EAX88921.1 - 0.16 12.4 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 Otx1 transcription factor Ras PF00071.22 EAX88922.1 - 3.8e-23 81.9 0.1 4.5e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88922.1 - 1.2e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88922.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX88922.1 - 7.9e-06 25.9 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX88922.1 - 0.00014 21.8 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EAX88922.1 - 0.00016 21.8 0.0 0.0095 16.0 0.0 2.3 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.6 EAX88922.1 - 0.00076 19.8 0.0 0.0019 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EAX88922.1 - 0.0012 18.2 0.1 0.0094 15.3 0.0 1.9 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 EAX88922.1 - 0.025 14.1 0.1 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EAX88922.1 - 0.035 13.5 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAX88922.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FOP_dimer PF09398.10 EAX88923.1 - 0.0078 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain DUF4226 PF10774.9 EAX88923.1 - 0.033 14.5 0.3 0.045 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Ras PF00071.22 EAX88924.1 - 2.3e-52 176.8 0.1 2.8e-52 176.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX88924.1 - 2e-16 60.3 0.0 3.8e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX88924.1 - 1.1e-07 31.4 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX88924.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PMT PF02366.18 EAX88925.1 - 1.7e-24 86.8 11.1 1.7e-24 86.8 11.1 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX88925.1 - 3.2e-22 79.1 11.9 3.2e-22 79.1 11.9 3.2 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase DUF202 PF02656.15 EAX88925.1 - 0.066 13.7 0.4 4.4 7.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ATP_synt_H PF05493.13 EAX88925.1 - 9.2 6.8 16.7 0.79 10.2 0.9 3.2 2 1 0 3 3 3 0 ATP synthase subunit H XK-related PF09815.9 EAX88926.1 - 1.6 7.7 14.5 0.04 13.0 3.4 2.0 1 1 1 2 2 2 0 XK-related protein DUF1619 PF07773.11 EAX88927.1 - 2.3e-08 34.3 16.2 2.3e-08 34.3 16.2 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1619) VPS9 PF02204.18 EAX88928.1 - 1.6e-12 47.5 0.1 1.3e-11 44.6 0.0 2.7 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 EAX88928.1 - 1.8e-07 31.1 9.6 8.8e-07 28.8 0.6 3.3 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase NPL PF17800.1 EAX88929.1 - 0.052 14.1 0.0 0.09 13.4 0.0 1.4 1 1 0 1 1 1 0 Nucleoplasmin-like domain ASH PF15780.5 EAX88930.1 - 5.8e-24 84.2 37.2 0.00071 19.7 0.0 16.3 18 1 0 18 18 18 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EAX88930.1 - 5.4e-16 58.4 38.3 0.00014 21.7 0.7 9.6 10 0 0 10 10 10 5 MSP (Major sperm protein) domain DUF1573 PF07610.11 EAX88930.1 - 2.2e-13 50.0 28.3 0.0016 18.4 0.8 12.0 12 0 0 12 12 12 4 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EAX88930.1 - 0.00074 19.7 27.1 4.9 7.5 0.1 10.7 11 0 0 11 11 11 2 Transmembrane protein 131-like fn3_5 PF06280.12 EAX88930.1 - 0.003 18.2 10.8 3.6 8.3 0.1 7.4 7 0 0 7 7 7 2 Fn3-like domain FixG_C PF11614.8 EAX88930.1 - 0.0084 16.3 9.6 0.41 10.9 0.0 5.8 6 0 0 6 6 6 2 IG-like fold at C-terminal of FixG, putative oxidoreductase GH115_C PF17829.1 EAX88930.1 - 0.049 13.5 0.0 0.25 11.2 0.0 2.2 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain UL16 PF17622.2 EAX88931.1 - 0.069 12.8 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Viral unique long protein 16 DUF4861 PF16153.5 EAX88932.1 - 0.0063 15.5 1.3 0.007 15.4 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) DUF4116 PF13475.6 EAX88932.1 - 0.031 14.0 1.5 0.05 13.3 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Tli4_C PF18426.1 EAX88932.1 - 0.087 13.1 0.4 0.13 12.6 0.4 1.4 1 1 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain adh_short_C2 PF13561.6 EAX88932.1 - 0.67 9.5 3.6 2.2 7.8 3.6 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TMP PF05017.14 EAX88934.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88935.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP SNase PF00565.17 EAX88936.1 - 2e-32 111.9 0.0 4.7e-07 30.3 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EAX88936.1 - 6e-09 36.0 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain P_proprotein PF01483.20 EAX88938.1 - 2.4e-05 24.3 0.0 0.00054 19.9 0.0 2.7 3 0 0 3 3 3 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 EAX88938.1 - 0.00017 20.9 1.5 0.067 12.5 0.3 2.2 2 0 0 2 2 2 2 Subtilase family NPL4 PF05021.15 EAX88940.1 - 5.5e-09 35.8 0.0 0.074 12.4 0.0 3.2 3 0 0 3 3 3 3 NPL4 family CLCA PF08434.11 EAX88941.1 - 0.00013 21.4 0.7 0.00038 19.9 0.1 2.0 2 0 0 2 2 2 1 Calcium-activated chloride channel N terminal PSP PF04046.16 EAX88945.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88946.1 - 0.043 14.4 6.6 4.4 8.4 0.4 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX88947.1 - 0.075 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX88949.1 - 7.1e-156 516.8 15.2 8.8e-156 516.5 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX88949.1 - 0.042 14.3 1.6 0.22 12.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX88949.1 - 0.23 11.3 1.6 0.54 10.1 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX88949.1 - 0.24 11.7 3.4 12 6.3 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX88949.1 - 1.1 9.8 7.1 1.7 9.1 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAX88951.1 - 7.8e-59 199.2 0.2 9.8e-59 198.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88951.1 - 2.9e-40 138.2 0.0 3.6e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX88951.1 - 4.2e-05 22.5 0.1 0.00012 20.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EAX88951.1 - 0.00014 21.3 0.0 0.008 15.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EAX88951.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX88951.1 - 0.0055 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX88951.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-bind_2 PF08914.11 EAX88951.1 - 0.2 11.8 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Pkinase PF00069.25 EAX88952.1 - 6.6e-61 206.0 0.0 9.4e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX88952.1 - 1.6e-38 132.5 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX88952.1 - 1.4e-06 27.9 0.1 0.00015 21.2 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EAX88952.1 - 3.3e-06 27.2 0.0 4.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX88952.1 - 6.1e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX88952.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EAX88952.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX88952.1 - 0.014 15.0 0.0 0.22 11.1 0.0 2.1 1 1 1 2 2 2 0 RIO1 family YukC PF10140.9 EAX88952.1 - 0.028 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 EAX88952.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Rho_GDI PF02115.17 EAX88952.1 - 0.063 13.0 0.3 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 RHO protein GDP dissociation inhibitor UCH PF00443.29 EAX88953.1 - 7.4e-05 22.4 0.2 8.5e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_4 PF13359.6 EAX88954.1 - 0.063 12.9 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease GPS2_interact PF15784.5 EAX88955.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88955.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAX88956.1 - 4.1e-20 71.7 0.1 5.2e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX88956.1 - 0.0082 16.1 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin HTH_Tnp_4 PF13613.6 EAX88957.1 - 4.6e-06 26.3 0.8 0.00031 20.4 0.5 2.2 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease FAR1 PF03101.15 EAX88958.1 - 0.0096 16.6 0.1 0.019 15.7 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Response_reg PF00072.24 EAX88959.1 - 3.6e-25 88.3 1.0 2.3e-24 85.7 0.2 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EAX88959.1 - 2.2e-23 82.9 0.3 1.2e-22 80.6 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EAX88959.1 - 1e-11 44.7 0.2 2.8e-11 43.3 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EAX88959.1 - 0.00062 20.0 0.2 0.013 15.8 0.1 2.8 2 0 0 2 2 2 1 PAS fold Ank_2 PF12796.7 EAX88960.1 - 2.2e-41 140.3 1.6 5.2e-16 59.0 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX88960.1 - 4.4e-30 102.8 0.3 5.7e-07 29.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX88960.1 - 2.6e-25 88.2 0.1 1.7e-11 44.1 0.0 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX88960.1 - 9.6e-25 86.6 0.8 4.2e-07 30.4 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88960.1 - 9.6e-25 84.0 0.3 2.3e-06 27.5 0.0 5.3 5 1 0 5 5 5 4 Ankyrin repeat HeH PF12949.7 EAX88960.1 - 0.047 13.4 0.9 14 5.5 0.0 2.9 3 0 0 3 3 3 0 HeH/LEM domain DUF3447 PF11929.8 EAX88961.1 - 5.4e-37 125.6 3.8 5.4e-37 125.6 3.8 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88961.1 - 1.5e-35 121.6 15.6 7.2e-12 45.7 0.4 6.4 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88961.1 - 1.6e-33 114.7 15.3 1.1e-11 45.0 0.1 8.5 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88961.1 - 8.1e-28 93.4 17.3 0.00016 21.8 0.1 10.3 11 1 2 13 13 13 6 Ankyrin repeat Ank PF00023.30 EAX88961.1 - 1.4e-26 91.7 11.2 8.1e-06 26.1 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX88961.1 - 3.8e-20 71.7 10.0 9.9e-07 28.9 0.2 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) APH PF01636.23 EAX88962.1 - 5.4e-21 75.6 0.0 1e-20 74.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX88962.1 - 1.8e-05 24.4 0.3 3.1e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EAX88962.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain HSBP1 PF06825.12 EAX88962.1 - 0.07 13.0 4.7 0.87 9.5 0.0 3.5 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Actin PF00022.19 EAX88963.1 - 9.2e-139 462.5 0.0 3.5e-138 460.6 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX88963.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT GPS2_interact PF15784.5 EAX88965.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX88965.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PTR PF12789.7 EAX88967.1 - 3e-16 59.2 1.9 3e-16 59.2 1.9 3.3 4 0 0 4 4 4 1 Phage tail repeat like TMP PF05017.14 EAX88969.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX88970.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Beach PF02138.18 EAX88971.1 - 2.2e-17 63.4 8.6 9.1e-12 44.9 0.7 3.8 3 1 1 4 4 4 2 Beige/BEACH domain PH_BEACH PF14844.6 EAX88971.1 - 7.1e-05 22.8 0.3 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Thoc2 PF11732.8 EAX88971.1 - 0.075 13.1 0.4 3.6 7.7 0.1 3.6 3 0 0 3 3 3 0 Transcription- and export-related complex subunit NIF PF03031.18 EAX88972.1 - 2.9e-17 62.9 0.5 6.8e-17 61.7 0.5 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EAX88972.1 - 3.5e-08 33.7 0.1 1.5e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAX88972.1 - 4.6e-05 23.7 0.1 0.00022 21.6 0.1 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EAX88972.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cyclin PF08613.11 EAX88973.1 - 1e-25 91.0 0.0 1.2e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EAX88973.1 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain PSP PF04046.16 EAX88974.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX88975.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX88976.1 - 3.6e-154 511.2 14.2 4.7e-154 510.8 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX88976.1 - 1.6 9.3 6.0 0.96 10.0 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX88976.1 - 2.5 8.6 7.0 2.1 8.8 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Synaptobrevin PF00957.21 EAX88978.1 - 6.9e-20 70.6 0.2 1.2e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAX88978.1 - 6.3e-08 32.6 0.1 2.8e-07 30.5 0.0 2.2 2 1 0 2 2 2 1 Regulated-SNARE-like domain DUF5345 PF17280.2 EAX88978.1 - 0.0027 17.7 0.9 0.0044 17.0 0.2 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5345) WBP-1 PF11669.8 EAX88978.1 - 0.0085 16.7 1.2 0.0085 16.7 1.2 1.9 2 1 0 2 2 2 1 WW domain-binding protein 1 DUF1910 PF08928.10 EAX88978.1 - 0.022 14.8 1.4 0.034 14.1 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Prominin PF05478.11 EAX88978.1 - 0.023 12.7 2.1 0.055 11.4 2.1 1.6 1 1 0 1 1 1 0 Prominin TraD_N PF12615.8 EAX88978.1 - 0.027 15.2 0.1 0.69 10.7 0.0 2.5 2 1 0 2 2 2 0 F sex factor protein N terminal Exonuc_VII_L PF02601.15 EAX88978.1 - 0.03 13.9 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC2_membrane_3 PF12698.7 EAX88978.1 - 0.05 12.7 1.4 0.08 12.0 1.4 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein FAM176 PF14851.6 EAX88979.1 - 0.0063 16.2 2.9 0.075 12.7 0.0 2.2 2 0 0 2 2 2 1 FAM176 family G0-G1_switch_2 PF15103.6 EAX88979.1 - 0.019 15.4 2.1 0.17 12.3 0.0 2.7 2 1 0 2 2 2 0 G0/G1 switch protein 2 DUF4834 PF16118.5 EAX88979.1 - 0.047 14.6 0.2 0.43 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3040 PF11239.8 EAX88979.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Zip PF02535.22 EAX88979.1 - 0.71 9.0 4.5 3.5 6.8 0.0 2.0 1 1 1 2 2 2 0 ZIP Zinc transporter DMT_6 PF04342.12 EAX88980.1 - 0.00013 22.2 1.0 0.00017 21.7 1.0 1.3 1 1 0 1 1 1 1 Putative member of DMT superfamily (DUF486) DsbD PF02683.15 EAX88980.1 - 0.026 14.4 0.7 0.026 14.4 0.7 1.4 1 1 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Cytochrom_B561 PF03188.16 EAX88980.1 - 0.03 14.5 1.9 0.044 13.9 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 AATF-Che1 PF13339.6 EAX88981.1 - 0.007 17.0 0.8 0.007 17.0 0.8 5.0 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor Csm1_N PF18504.1 EAX88981.1 - 0.025 14.9 5.5 0.025 14.9 5.5 6.4 6 3 2 8 8 8 0 Csm1 N-terminal domain Tox-REase-5 PF15648.6 EAX88981.1 - 0.41 11.2 11.6 0.22 12.1 2.5 4.1 5 0 0 5 5 5 0 Restriction endonuclease fold toxin 5 Mod_r PF07200.13 EAX88981.1 - 0.77 9.9 69.4 0.04 14.0 13.2 5.4 1 1 4 5 5 5 0 Modifier of rudimentary (Mod(r)) protein DUF4618 PF15397.6 EAX88981.1 - 2.9 7.2 56.6 0.65 9.4 6.2 5.9 1 1 3 5 5 5 0 Domain of unknown function (DUF4618) FliJ PF02050.16 EAX88981.1 - 5.9 7.1 55.9 0.72 10.1 1.5 6.1 2 1 3 6 6 6 0 Flagellar FliJ protein Sec7_N PF12783.7 EAX88982.1 - 0.0058 16.6 0.9 0.0058 16.6 0.9 5.8 3 2 4 8 8 8 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 EAX88982.1 - 0.011 15.9 0.1 9.6 6.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EAX88982.1 - 0.2 12.3 8.0 0.88 10.2 0.0 5.1 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region LRR_9 PF14580.6 EAX88983.1 - 2.8e-12 46.5 8.0 2.8e-12 46.5 8.0 2.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EAX88983.1 - 2.8e-05 23.8 14.1 0.00017 21.3 3.8 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EAX88983.1 - 8.8e-05 22.5 4.3 0.61 10.9 0.1 4.7 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 EAX88983.1 - 0.00011 22.5 11.7 0.0003 21.1 3.9 5.6 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) Cnn_1N PF07989.11 EAX88983.1 - 0.013 15.6 11.7 0.013 15.6 11.7 9.5 4 2 3 8 8 8 0 Centrosomin N-terminal motif 1 LRR_6 PF13516.6 EAX88983.1 - 0.036 14.1 15.5 0.27 11.4 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Rnk_N PF14760.6 EAX88983.1 - 0.15 12.5 1.6 0.68 10.5 0.2 2.8 2 0 0 2 2 2 0 Rnk N-terminus DUF563 PF04577.14 EAX88984.1 - 1.9e-31 109.9 0.5 2.7e-31 109.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PRA-PH PF01503.17 EAX88985.1 - 0.32 11.5 2.6 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase CAP_N PF01213.19 EAX88986.1 - 0.066 12.7 5.2 0.07 12.6 5.2 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EpuA PF11772.8 EAX88987.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Thg1C PF14413.6 EAX88987.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain Gly_rich PF12810.7 EAX88988.1 - 5.2e-37 128.1 25.3 6.6e-37 127.7 25.3 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAX88989.1 - 9.7e-41 137.6 3.6 9.7e-41 137.6 3.6 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX88989.1 - 5.8e-30 103.7 5.4 6.8e-17 61.8 0.5 4.3 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX88989.1 - 6.9e-28 96.7 5.3 6.7e-10 39.3 0.2 6.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX88989.1 - 2.2e-26 91.1 0.2 5.1e-08 33.0 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAX88989.1 - 1.9e-21 73.8 3.5 1.4e-05 25.0 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX88989.1 - 2.3e-20 72.4 7.6 2e-09 37.5 0.2 5.4 3 1 2 6 6 6 3 Ankyrin repeats (many copies) T4_Gp59_N PF08993.10 EAX88989.1 - 0.042 14.3 4.5 5.2 7.5 0.1 3.8 2 1 2 4 4 4 0 T4 gene Gp59 loader of gp41 DNA helicase Ank_4 PF13637.6 EAX88990.1 - 3.9e-94 307.9 42.8 2.9e-13 50.0 0.2 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX88990.1 - 6.5e-87 282.5 21.5 4.4e-09 36.4 0.0 10.0 10 0 0 10 10 10 10 Ankyrin repeat Ank_2 PF12796.7 EAX88990.1 - 3e-71 236.0 36.0 3.1e-18 66.1 3.2 6.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX88990.1 - 2.4e-65 215.7 28.1 8e-14 51.5 0.1 6.4 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX88990.1 - 1e-61 197.6 23.8 1.7e-06 27.9 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat MetallophosN PF16371.5 EAX88990.1 - 1.4e-17 63.7 0.0 0.00019 21.6 0.0 6.0 1 1 4 6 6 6 4 N terminal of Calcineurin-like phosphoesterase CEP44 PF15007.6 EAX88990.1 - 2.1e-12 47.3 0.3 1 9.6 0.0 7.3 1 1 8 9 9 9 3 Centrosomal spindle body, CEP44 Staphylokinase PF02821.16 EAX88990.1 - 3.2e-09 37.3 4.5 11 6.4 0.0 7.6 1 1 7 8 8 8 0 Staphylokinase/Streptokinase family Mic1 PF07035.12 EAX88990.1 - 1.8e-06 27.7 0.2 0.95 9.2 0.0 5.2 4 1 2 6 6 6 2 Colon cancer-associated protein Mic1-like AnkUBD PF18418.1 EAX88990.1 - 0.00013 22.1 0.0 47 4.2 0.0 5.9 1 1 6 7 7 7 0 Ankyrin ubiquitin-binding domain Sigma70_r4_2 PF08281.12 EAX88990.1 - 0.00024 20.7 6.0 5.7 6.7 0.0 7.3 9 0 0 9 9 9 1 Sigma-70, region 4 RelA_SpoT PF04607.17 EAX88990.1 - 0.00029 21.1 0.9 26 5.2 0.0 4.6 1 1 3 4 4 4 0 Region found in RelA / SpoT proteins PTS_EIIA_1 PF00358.20 EAX88990.1 - 0.00076 19.2 0.1 20 5.0 0.0 4.8 1 1 4 5 5 5 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 T4_Gp59_N PF08993.10 EAX88990.1 - 0.0018 18.6 14.9 4.6 7.7 0.3 7.2 1 1 8 9 9 9 1 T4 gene Gp59 loader of gp41 DNA helicase DUF3130 PF11328.8 EAX88990.1 - 0.0023 18.1 2.7 27 5.1 0.0 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF3130 Mqo PF06039.15 EAX88990.1 - 0.0027 16.3 0.3 0.095 11.2 0.1 3.0 1 1 3 4 4 4 1 Malate:quinone oxidoreductase (Mqo) PH_8 PF15409.6 EAX88990.1 - 0.0035 17.6 4.6 7.4 6.9 0.0 6.0 1 1 6 7 7 7 1 Pleckstrin homology domain BRCT_2 PF16589.5 EAX88990.1 - 0.012 16.0 7.4 5.1e+02 1.2 7.4 5.2 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BNR_3 PF13859.6 EAX88990.1 - 0.013 14.8 0.0 1.6 7.9 0.0 2.5 1 1 1 2 2 2 0 BNR repeat-like domain B5 PF03484.15 EAX88990.1 - 0.027 14.8 3.1 74 3.8 0.0 5.3 5 2 1 6 6 5 0 tRNA synthetase B5 domain DUF3157 PF11355.8 EAX88990.1 - 0.2 11.3 7.7 11 5.5 0.1 4.5 2 2 1 4 4 4 0 Protein of unknown function (DUF3157) CooC_C PF15976.5 EAX88990.1 - 0.83 9.7 3.7 23 5.1 0.1 3.6 3 1 0 4 4 4 0 CS1-pili formation C-terminal ThiS-like PF14453.6 EAX88990.1 - 1.1 9.4 21.1 39 4.4 0.1 7.7 1 1 6 9 9 9 0 ThiS-like ubiquitin RE_SinI PF09570.10 EAX88990.1 - 1.9 7.7 6.8 33 3.6 0.1 3.4 4 0 0 4 4 4 0 SinI restriction endonuclease F5_F8_type_C PF00754.25 EAX88991.1 - 0.00062 19.9 0.0 0.00099 19.2 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain LRR_4 PF12799.7 EAX88992.1 - 7.7e-23 80.2 52.9 1.6e-05 25.1 10.7 7.0 3 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX88992.1 - 1.5e-12 47.0 46.9 0.00024 20.8 6.9 6.5 2 1 6 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 EAX88992.1 - 3.5e-08 33.2 23.9 0.0017 17.9 7.9 4.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EAX88992.1 - 1e-06 28.3 20.8 0.025 14.6 0.1 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EAX88992.1 - 0.0021 18.4 35.2 4.4 8.2 1.6 8.6 7 1 1 8 8 8 3 Leucine Rich Repeat ArsC PF03960.15 EAX88992.1 - 0.053 13.5 1.3 0.14 12.2 0.0 2.4 2 1 0 2 2 2 0 ArsC family DUF4710 PF15828.5 EAX88994.1 - 0.018 15.2 1.0 0.03 14.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF4106 PF13388.6 EAX88995.1 - 1.6e-264 877.5 15.5 1.6e-264 877.5 15.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX88995.1 - 0.068 13.5 2.5 1.1 9.6 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated ABC_tran PF00005.27 EAX88996.1 - 7.8e-36 123.6 0.0 1.8e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAX88996.1 - 8.3e-28 97.8 12.8 1.2e-27 97.2 12.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EAX88996.1 - 1.8e-06 27.5 0.6 7.8e-05 22.2 0.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EAX88996.1 - 0.00024 20.4 0.0 0.0029 16.9 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 EAX88996.1 - 0.0023 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAX88996.1 - 0.0025 17.8 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EAX88996.1 - 0.0029 17.4 0.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EAX88996.1 - 0.0041 17.5 0.3 0.23 11.9 0.2 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX88996.1 - 0.0052 17.2 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EAX88996.1 - 0.03 14.5 0.1 0.08 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX88996.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX88996.1 - 0.05 13.6 0.1 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAX88996.1 - 0.05 13.3 0.1 0.16 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX88996.1 - 0.093 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Grg1 PF11034.8 EAX88996.1 - 0.095 12.9 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 DUF3284 PF11687.8 EAX88997.1 - 0.029 14.2 0.9 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) Synaptobrevin PF00957.21 EAX88998.1 - 8e-15 54.4 0.0 1.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAX88998.1 - 1.4e-06 28.2 0.3 3.3e-06 27.0 0.3 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain HEPN_Apea PF18739.1 EAX88998.1 - 0.13 12.7 1.9 1 9.8 0.4 2.2 2 0 0 2 2 2 0 Apea-like HEPN Sec5 PF15469.6 EAX88998.1 - 0.27 11.0 4.0 0.46 10.3 0.9 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 Ank_3 PF13606.6 EAX89000.1 - 6.3e-05 23.1 0.0 0.48 11.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EAX89000.1 - 0.0003 21.3 0.2 0.00089 19.8 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Laminin_I PF06008.14 EAX89000.1 - 0.00069 19.4 15.0 0.00098 18.9 15.0 1.2 1 0 0 1 1 1 1 Laminin Domain I WEMBL PF05701.11 EAX89000.1 - 0.00091 18.0 5.9 0.001 17.9 5.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Ank_4 PF13637.6 EAX89000.1 - 0.0017 18.9 2.3 0.032 14.8 0.1 3.3 3 1 0 3 3 2 1 Ankyrin repeats (many copies) ERM PF00769.19 EAX89000.1 - 0.0022 17.9 5.4 0.0034 17.2 5.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HALZ PF02183.18 EAX89000.1 - 0.0035 17.5 1.9 0.0035 17.5 1.9 2.3 3 0 0 3 3 1 1 Homeobox associated leucine zipper FPP PF05911.11 EAX89000.1 - 0.0037 15.5 13.1 0.0045 15.3 13.1 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ADIP PF11559.8 EAX89000.1 - 0.0068 16.5 18.1 0.021 14.9 17.6 1.9 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 EAX89000.1 - 0.0074 16.5 7.6 0.0074 16.5 7.6 2.7 2 1 1 3 3 2 1 Fibrinogen alpha/beta chain family Ank_5 PF13857.6 EAX89000.1 - 0.017 15.4 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TolA_bind_tri PF16331.5 EAX89000.1 - 0.026 14.6 3.1 0.026 14.6 3.1 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 EAX89000.1 - 0.033 13.9 22.4 0.17 11.7 5.1 3.4 1 1 2 3 3 3 0 Septum formation initiator Spc7 PF08317.11 EAX89000.1 - 0.048 12.5 16.6 0.039 12.8 9.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Rootletin PF15035.6 EAX89000.1 - 0.05 13.6 12.1 0.044 13.8 10.8 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.8 EAX89000.1 - 0.054 12.8 13.0 0.049 12.9 11.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 EAX89000.1 - 0.065 12.8 15.0 0.2 11.2 14.9 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4201 PF13870.6 EAX89000.1 - 0.072 12.8 17.5 1.9 8.2 17.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 EAX89000.1 - 0.12 13.0 6.7 2 9.1 6.7 2.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 EAX89000.1 - 0.13 11.6 16.1 0.18 11.2 16.1 1.2 1 0 0 1 1 1 0 FAM76 protein KASH_CCD PF14662.6 EAX89000.1 - 0.13 12.0 17.3 0.015 15.1 12.9 1.6 2 0 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EAX89000.1 - 0.14 12.3 9.0 0.22 11.7 2.2 3.1 2 1 0 2 2 2 0 bZIP transcription factor NRBF2 PF08961.10 EAX89000.1 - 0.15 11.7 13.4 0.12 12.0 10.7 2.2 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator APG6_N PF17675.1 EAX89000.1 - 0.17 12.4 11.1 0.44 11.1 11.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region HrpB7 PF09486.10 EAX89000.1 - 0.18 12.2 3.8 1.1 9.7 0.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 EAX89000.1 - 0.18 12.2 12.4 0.25 11.7 11.5 1.6 1 1 0 1 1 1 0 Fez1 DUF3987 PF13148.6 EAX89000.1 - 0.27 10.2 2.4 0.38 9.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TMF_TATA_bd PF12325.8 EAX89000.1 - 0.34 11.2 8.6 0.6 10.4 4.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.11 EAX89000.1 - 0.45 11.1 9.3 1.4 9.5 9.3 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CEP209_CC5 PF16574.5 EAX89000.1 - 0.46 10.7 15.0 0.15 12.2 5.3 2.6 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 Phage_GP20 PF06810.11 EAX89000.1 - 0.48 10.2 19.3 1.2 8.9 12.0 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 EAX89000.1 - 0.48 10.6 16.6 1.1 9.4 6.4 2.3 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 EAX89000.1 - 0.54 10.6 10.6 6.5 7.2 0.1 3.2 1 1 1 2 2 2 0 Csm1 N-terminal domain zf-C4H2 PF10146.9 EAX89000.1 - 0.56 10.5 14.3 0.52 10.6 12.9 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein SCP-1 PF05483.12 EAX89000.1 - 0.72 7.8 23.7 0.99 7.3 22.9 1.5 1 1 1 2 2 2 0 Synaptonemal complex protein 1 (SCP-1) V_ATPase_I PF01496.19 EAX89000.1 - 0.94 7.3 12.0 1.1 7.0 12.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EAX89000.1 - 1.2 9.2 19.9 0.031 14.3 9.0 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 EAX89000.1 - 1.4 9.9 13.5 0.92 10.4 1.7 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 EAX89000.1 - 1.5 9.0 15.4 2.6 8.2 11.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EAX89000.1 - 1.6 8.9 18.7 0.28 11.3 11.2 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3800 PF12686.7 EAX89000.1 - 1.7 9.3 11.8 6.6 7.4 11.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4407 PF14362.6 EAX89000.1 - 1.9 7.8 12.4 18 4.6 12.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EAX89000.1 - 2 8.7 13.9 7.1 6.8 13.1 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MIP-T3_C PF17749.1 EAX89000.1 - 2 8.4 18.7 0.39 10.7 7.6 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region FlaC_arch PF05377.11 EAX89000.1 - 2.1 8.8 11.1 1.2 9.6 1.9 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 EAX89000.1 - 2.6 8.4 11.8 7.1 7.0 1.2 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 EAX89000.1 - 2.7 7.1 12.9 0.16 11.1 5.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein TRAF_BIRC3_bd PF16673.5 EAX89000.1 - 2.9 7.7 9.8 0.3 10.9 2.0 2.5 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Prominin PF05478.11 EAX89000.1 - 3.5 5.4 18.2 6.7 4.5 18.3 1.4 1 1 0 1 1 1 0 Prominin CENP-H PF05837.12 EAX89000.1 - 4 7.9 10.5 2.1 8.8 7.6 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Lebercilin PF15619.6 EAX89000.1 - 4.1 7.0 21.9 0.54 9.9 10.0 2.8 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EAX89000.1 - 4.6 7.3 10.0 3.2 7.8 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EAX89000.1 - 4.7 7.5 9.5 7.9 6.8 6.1 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain FlxA PF14282.6 EAX89000.1 - 5.6 7.0 22.8 1.3e+03 -0.6 22.8 2.9 1 1 0 1 1 1 0 FlxA-like protein Swi5 PF07061.11 EAX89000.1 - 6.7 6.9 19.6 4.2 7.5 6.1 2.8 1 1 0 2 2 2 0 Swi5 YabA PF06156.13 EAX89000.1 - 6.8 7.4 15.1 9.8 6.9 10.4 2.6 1 1 2 3 3 2 0 Initiation control protein YabA Cnn_1N PF07989.11 EAX89000.1 - 7.2 6.9 16.3 0.91 9.7 9.4 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 EAX89000.1 - 8.1 7.0 9.2 7.9e+02 0.6 9.3 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 EAX89000.1 - 9 7.0 12.6 2.3 8.9 7.8 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ZapB PF06005.12 EAX89000.1 - 9.8 6.7 16.2 26 5.4 14.5 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Metallophos PF00149.28 EAX89001.1 - 2.5e-13 51.0 0.1 3.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX89001.1 - 2.1e-09 37.8 0.0 2.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAX89002.1 - 8.6e-34 117.8 0.1 1.3e-33 117.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EAX89002.1 - 0.033 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Bromodomain PF00439.25 EAX89002.1 - 0.076 13.1 0.0 7.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Bromodomain RhoGEF PF00621.20 EAX89002.1 - 0.13 12.5 0.3 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 RhoGEF domain Metallophos_2 PF12850.7 EAX89002.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PGP_phosphatase PF09419.10 EAX89003.1 - 0.028 14.1 2.2 0.049 13.2 2.2 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DUF4407 PF14362.6 EAX89003.1 - 0.093 12.1 27.9 0.34 10.2 16.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EAX89003.1 - 0.44 10.6 17.2 0.66 10.0 8.9 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EAX89003.1 - 0.52 10.8 39.2 1.2 9.7 9.3 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 EAX89003.1 - 1.7 9.2 26.3 0.49 10.9 2.9 4.0 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 EAX89003.1 - 2.5 8.4 33.1 0.5 10.6 6.3 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Hira PF07569.11 EAX89003.1 - 2.9 7.5 7.9 4.5 6.9 7.9 1.5 1 1 0 1 1 1 0 TUP1-like enhancer of split Peptidase_S46 PF10459.9 EAX89003.1 - 3.2 6.3 19.2 3.9 6.0 19.2 1.1 1 0 0 1 1 1 0 Peptidase S46 F5_F8_type_C PF00754.25 EAX89004.1 - 1.7e-08 34.6 0.0 1.5e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 F5/8 type C domain DUF1031 PF06275.11 EAX89006.1 - 0.043 14.1 0.0 0.065 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) Annexin PF00191.20 EAX89006.1 - 0.053 13.6 0.3 0.33 11.1 0.2 2.1 1 1 1 2 2 2 0 Annexin HARE-HTH PF05066.13 EAX89006.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Sec23_helical PF04815.15 EAX89006.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Ank_2 PF12796.7 EAX89007.1 - 1.9e-40 137.3 6.3 2.7e-12 47.1 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89007.1 - 4e-36 122.9 3.1 1.7e-08 34.8 0.0 7.9 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89007.1 - 1.6e-33 110.9 1.8 0.00085 19.6 0.0 10.2 9 2 1 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX89007.1 - 5e-23 80.9 1.5 0.00025 21.3 0.0 7.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX89007.1 - 3.8e-20 71.4 0.3 0.0005 20.4 0.0 7.4 6 1 1 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX89007.1 - 1.6e-18 66.4 15.2 1.3e-12 47.5 1.5 5.1 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) DUF1866 PF08952.11 EAX89007.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) ApoB100_C PF12491.8 EAX89007.1 - 0.21 11.6 3.1 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal TPR_MLP1_2 PF07926.12 EAX89008.1 - 0.66 10.0 11.4 4.3 7.4 0.2 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.6 EAX89008.1 - 0.69 10.1 11.8 0.69 10.1 5.5 2.4 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MitMem_reg PF13012.6 EAX89008.1 - 0.71 10.3 8.2 2.9 8.3 5.0 2.7 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function ABC_tran_CTD PF16326.5 EAX89008.1 - 5.9 7.2 12.6 38 4.6 0.1 3.9 2 2 1 3 3 3 0 ABC transporter C-terminal domain PEHE PF15275.6 EAX89008.1 - 8.4 7.0 8.9 4.1 8.0 0.6 2.9 2 1 1 3 3 3 0 PEHE domain PhoLip_ATPase_C PF16212.5 EAX89009.1 - 2e-63 214.4 24.1 2e-63 214.4 24.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAX89009.1 - 5.2e-20 70.9 1.2 2.1e-19 69.0 1.2 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EAX89009.1 - 5.6e-12 45.6 0.3 1.8e-10 40.7 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAX89009.1 - 1.2e-11 44.5 0.0 8.3e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAX89009.1 - 2.4e-07 31.3 0.4 0.0026 18.1 0.3 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAX89009.1 - 0.043 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 EAX89010.1 - 1.2e-08 34.9 0.1 0.0005 20.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Tctex-1 PF03645.13 EAX89011.1 - 3.1e-24 85.2 1.5 3.3e-24 85.1 1.5 1.0 1 0 0 1 1 1 1 Tctex-1 family Ank_5 PF13857.6 EAX89012.1 - 6.1e-28 96.5 1.2 7.5e-09 35.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89012.1 - 6e-25 87.3 5.8 1.6e-12 47.7 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89012.1 - 2.2e-24 84.8 4.6 4.2e-09 36.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAX89012.1 - 5e-24 84.7 5.9 3.6e-15 56.3 3.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89012.1 - 3e-21 73.2 1.1 8e-07 28.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat MCC-bdg_PDZ PF10506.9 EAX89012.1 - 0.0077 16.2 0.5 8.9 6.4 0.0 3.0 3 0 0 3 3 3 2 PDZ domain of MCC-2 bdg protein for Usher syndrome CCDC84 PF14968.6 EAX89012.1 - 0.053 13.2 1.7 2.6 7.6 0.0 2.4 1 1 1 2 2 2 0 Coiled coil protein 84 LuxT_C PF18285.1 EAX89012.1 - 0.11 13.0 0.1 2.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Tetracycline repressor LuxT C-terminal domain Toxin_13 PF07822.11 EAX89012.1 - 0.16 12.2 2.4 0.19 11.9 0.1 2.4 3 1 0 3 3 3 0 Neurotoxin B-IV-like protein Ank_4 PF13637.6 EAX89013.1 - 9.3e-32 109.0 6.7 3.5e-09 37.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX89013.1 - 8.8e-31 105.0 4.2 8.1e-08 32.4 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 EAX89013.1 - 1.8e-26 92.5 6.6 3.9e-15 56.2 0.5 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89013.1 - 1.6e-25 88.8 2.5 1.3e-09 38.1 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89013.1 - 6.4e-22 75.3 8.5 4.9e-06 26.5 0.1 5.3 6 0 0 6 6 6 4 Ankyrin repeat Hydrolase_3 PF08282.12 EAX89013.1 - 0.00092 19.0 5.9 0.0023 17.7 1.5 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SCVP PF17619.2 EAX89013.1 - 0.055 14.3 0.4 0.61 11.0 0.0 2.5 1 1 1 3 3 3 0 Secreted clade V proteins nsp7 PF08716.10 EAX89013.1 - 0.12 13.1 0.5 0.8 10.4 0.1 2.3 1 1 0 2 2 2 0 nsp7 replicase Ank_2 PF12796.7 EAX89014.1 - 1.3e-20 73.7 7.1 1.6e-11 44.6 1.4 3.6 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX89014.1 - 3.1e-19 68.7 9.1 3.1e-19 68.7 9.1 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX89014.1 - 8.1e-17 61.4 0.4 8.2e-09 35.8 0.2 4.8 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89014.1 - 2.2e-11 42.9 2.1 0.043 14.4 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX89014.1 - 2.7e-11 43.5 0.7 2.1e-06 27.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX89014.1 - 3.5e-10 39.9 0.0 0.0013 19.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat aGPT-Pplase3 PF18746.1 EAX89014.1 - 0.04 13.3 0.0 0.43 9.9 0.1 2.3 1 1 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 DUF4709 PF15821.5 EAX89015.1 - 0.059 13.7 0.1 0.078 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) RNA_pol_A_CTD PF03118.15 EAX89015.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Retinin_C PF04527.12 EAX89017.1 - 7.2e-06 26.2 84.2 23 5.4 0.3 15.2 15 0 0 15 15 15 15 Drosophila Retinin like protein FliG_C PF01706.16 EAX89017.1 - 4 7.7 53.1 1.4e+02 2.7 0.1 14.3 1 1 15 16 16 16 0 FliG C-terminal domain Guanylate_cyc PF00211.20 EAX89018.1 - 9e-44 149.3 0.1 1.7e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX89018.1 - 0.0001 22.5 0.4 0.00032 20.9 0.4 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX89018.1 - 0.00061 19.8 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAX89018.1 - 0.011 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain YibE_F PF07907.11 EAX89018.1 - 0.077 12.5 1.7 0.35 10.3 0.1 2.4 2 0 0 2 2 2 0 YibE/F-like protein DUF4064 PF13273.6 EAX89018.1 - 3.6 7.9 8.6 8.4 6.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Arm PF00514.23 EAX89020.1 - 0.00049 20.0 0.1 0.058 13.5 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RCC1 PF00415.18 EAX89021.1 - 3.9e-17 62.6 10.3 3.9e-05 24.2 0.2 6.7 6 1 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAX89021.1 - 8.6e-16 57.3 23.0 7.1e-07 28.9 0.6 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SPASM PF13186.6 EAX89021.1 - 0.0041 17.6 0.4 13 6.4 0.0 4.2 4 0 0 4 4 4 2 Iron-sulfur cluster-binding domain Myb_DNA-binding PF00249.31 EAX89022.1 - 4.9e-32 109.9 5.0 2.2e-15 56.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89022.1 - 1e-28 99.3 1.5 2.5e-16 59.7 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89022.1 - 3.6e-06 26.8 2.0 7.5e-05 22.5 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX89022.1 - 0.0001 22.3 0.2 0.23 11.5 0.0 2.2 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX89022.1 - 0.0015 18.6 2.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EAX89022.1 - 0.0081 16.3 0.3 0.17 12.1 0.0 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 HTH_23 PF13384.6 EAX89022.1 - 0.046 13.5 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 EAX89022.1 - 0.54 10.7 5.9 0.84 10.1 1.3 2.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TMP PF05017.14 EAX89024.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX89024.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX89025.1 - 0.03 14.8 0.8 0.063 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89026.1 - 1.7e-21 76.1 22.1 1.4e-16 60.3 1.9 5.4 6 1 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX89026.1 - 0.078 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX89026.1 - 5.9 6.4 16.7 0.16 11.6 3.4 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX89029.1 - 9e-159 526.3 13.1 1.1e-158 526.0 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX89029.1 - 0.39 11.0 3.8 13 6.2 0.0 3.6 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX89029.1 - 3.4 8.2 8.0 2.6 8.6 0.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DDR PF08841.10 EAX89030.1 - 0.044 12.8 0.2 0.044 12.8 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain zf-MYST PF17772.1 EAX89033.1 - 0.16 11.6 4.5 0.081 12.5 1.6 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain GAS PF13851.6 EAX89033.1 - 8.5 5.7 46.1 2.3 7.5 8.5 3.0 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Serinc PF03348.15 EAX89034.1 - 0.079 11.9 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 EAX89035.1 - 1.5e-19 70.4 0.0 1.3e-10 40.9 0.0 3.0 1 1 2 3 3 3 3 Solute carrier family 12 MGC-24 PF05283.11 EAX89037.1 - 2.3 8.7 5.0 3.4 8.1 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_2 PF12796.7 EAX89039.1 - 3.5e-16 59.6 0.7 4.5e-12 46.4 0.0 3.7 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89039.1 - 8.9e-13 48.5 0.1 3.2e-10 40.3 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX89039.1 - 1.7e-07 31.3 0.0 0.03 14.8 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX89039.1 - 6.1e-07 29.3 1.6 0.022 15.3 0.0 5.1 6 0 0 6 6 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX89039.1 - 6.2e-07 29.6 0.2 9.5e-06 25.8 0.1 2.8 2 1 1 3 3 2 1 Ankyrin repeats (many copies) LisH_TPL PF17814.1 EAX89039.1 - 0.0099 15.5 2.4 6.1 6.6 0.1 3.3 3 0 0 3 3 3 2 LisH-like dimerisation domain bZIP_1 PF00170.21 EAX89039.1 - 0.029 14.5 1.1 0.029 14.5 1.1 4.2 2 1 1 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 EAX89039.1 - 0.12 12.7 0.4 0.12 12.7 0.4 4.8 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4795 PF16043.5 EAX89039.1 - 0.17 11.4 20.6 0.73 9.4 11.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) UPF0242 PF06785.11 EAX89039.1 - 1.5 8.9 34.6 0.4 10.8 27.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 EAX89039.1 - 2.7 8.3 8.3 18 5.7 0.3 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper GvpK PF05121.12 EAX89039.1 - 6.1 7.0 7.1 16 5.6 0.2 3.3 1 1 1 3 3 3 0 Gas vesicle protein K ABC_tran_CTD PF16326.5 EAX89039.1 - 6.9 7.0 21.1 1.3 9.3 3.2 3.9 4 1 0 4 4 3 0 ABC transporter C-terminal domain NTP_transferase PF00483.23 EAX89040.1 - 1.5e-28 100.1 0.0 2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EAX89040.1 - 5.4e-10 39.9 0.0 7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EAX89040.1 - 7e-09 35.1 16.0 2.8e-05 23.6 0.4 4.6 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EAX89040.1 - 0.00044 19.3 2.3 0.00091 18.3 2.3 1.5 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EAX89040.1 - 0.0027 15.9 1.7 0.0042 15.3 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EAX89040.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase FOXO_KIX_bdg PF16675.5 EAX89040.1 - 0.067 13.5 0.0 0.26 11.6 0.0 2.0 3 0 0 3 3 3 0 KIX-binding domain of forkhead box O, CR2 Hexapep_2 PF14602.6 EAX89040.1 - 0.18 11.6 18.3 4.6 7.1 7.6 4.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Lipase_3 PF01764.25 EAX89041.1 - 7.9e-16 58.2 0.0 1.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAX89041.1 - 0.00011 22.9 0.0 0.00013 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4448 PF14610.6 EAX89041.1 - 0.0014 18.4 0.2 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF676 PF05057.14 EAX89041.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TMEM154 PF15102.6 EAX89041.1 - 0.023 14.6 1.7 0.039 13.9 1.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family Abhydrolase_5 PF12695.7 EAX89041.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EAX89041.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF5383 PF17355.2 EAX89041.1 - 0.064 13.6 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) PGAP1 PF07819.13 EAX89041.1 - 0.082 12.6 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Insulin_TMD PF17870.1 EAX89041.1 - 4.7 7.4 6.5 8.5 6.5 2.7 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TGase_elicitor PF16683.5 EAX89042.1 - 0.1 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor TPH PF13868.6 EAX89043.1 - 1.8e-45 155.0 168.4 1.8e-45 155.0 168.4 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ank_2 PF12796.7 EAX89044.1 - 1.2e-78 259.8 27.9 1.6e-12 47.8 0.0 8.5 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89044.1 - 2e-56 187.7 25.8 1.9e-11 44.2 0.3 14.7 5 5 11 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89044.1 - 4.9e-49 163.7 25.2 4.8e-08 33.1 0.3 13.7 5 4 10 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89044.1 - 2.6e-46 150.2 22.5 2e-05 24.6 0.1 16.0 17 0 0 17 17 17 11 Ankyrin repeat Ank PF00023.30 EAX89044.1 - 5.5e-33 112.0 25.0 4.9e-06 26.7 0.2 13.3 15 1 0 15 15 15 7 Ankyrin repeat PPR_3 PF13812.6 EAX89044.1 - 0.0012 18.9 1.1 6.9 6.8 0.1 4.3 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Plant_tran PF04827.14 EAX89044.1 - 0.0047 16.6 0.9 0.59 9.7 0.2 3.0 2 1 1 3 3 3 1 Plant transposon protein DUF3447 PF11929.8 EAX89044.1 - 0.061 13.3 0.4 0.061 13.3 0.4 4.9 5 2 1 6 6 6 0 Domain of unknown function (DUF3447) Myb_DNA-binding PF00249.31 EAX89045.1 - 4.6e-05 23.5 0.0 6.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89045.1 - 0.0081 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Metallophos PF00149.28 EAX89046.1 - 3.4e-28 99.5 0.2 4.6e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX89046.1 - 0.019 15.2 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EAX89046.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PRTase_3 PF15610.6 EAX89046.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Ank_2 PF12796.7 EAX89047.1 - 9.1e-81 266.5 6.3 1.1e-19 70.7 0.0 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89047.1 - 4.3e-45 151.5 0.7 2.4e-09 37.5 0.0 5.5 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89047.1 - 7.2e-43 144.1 0.6 4.5e-06 26.8 0.0 7.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX89047.1 - 8.4e-42 139.8 0.0 4.8e-05 23.6 0.0 8.0 8 0 0 8 8 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX89047.1 - 2.4e-34 113.5 0.0 0.0011 19.3 0.0 8.0 8 0 0 8 8 7 6 Ankyrin repeat Spc7 PF08317.11 EAX89047.1 - 0.0001 21.3 10.9 0.00015 20.7 10.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4763 PF15960.5 EAX89047.1 - 0.00019 20.8 5.4 0.00019 20.8 5.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Exonuc_VII_L PF02601.15 EAX89047.1 - 0.00025 20.7 3.6 0.00035 20.2 3.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Laminin_II PF06009.12 EAX89047.1 - 0.00029 20.9 11.9 0.00069 19.6 11.9 1.6 1 0 0 1 1 1 1 Laminin Domain II DUF773 PF05600.12 EAX89047.1 - 0.00066 18.5 8.2 0.00096 18.0 8.2 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF3450 PF11932.8 EAX89047.1 - 0.0007 19.0 9.3 0.0012 18.2 9.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 EAX89047.1 - 0.0016 18.1 7.0 0.0023 17.6 7.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EAX89047.1 - 0.0018 18.5 8.1 0.0027 17.9 8.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EAX89047.1 - 0.0021 16.8 14.3 0.0029 16.3 14.3 1.2 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 EAX89047.1 - 0.0031 18.0 13.2 0.0057 17.2 13.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Golgin_A5 PF09787.9 EAX89047.1 - 0.0039 16.7 7.5 0.006 16.1 7.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 UPF0242 PF06785.11 EAX89047.1 - 0.0044 17.2 11.1 0.0069 16.5 11.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EAX89047.1 - 0.0052 16.8 5.2 0.012 15.6 5.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) EzrA PF06160.12 EAX89047.1 - 0.0067 14.7 18.4 0.011 14.0 18.4 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 EAX89047.1 - 0.0078 14.5 12.6 0.011 14.0 12.6 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil OmpH PF03938.14 EAX89047.1 - 0.008 16.5 12.1 0.016 15.6 12.1 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) ERM PF00769.19 EAX89047.1 - 0.0084 16.0 8.0 0.013 15.4 8.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF641 PF04859.12 EAX89047.1 - 0.01 16.2 4.2 0.023 15.0 4.2 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.7 EAX89047.1 - 0.015 15.5 18.2 0.026 14.7 18.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DHR10 PF18595.1 EAX89047.1 - 0.018 15.1 9.9 0.036 14.1 9.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tropomyosin PF00261.20 EAX89047.1 - 0.027 13.8 10.0 0.043 13.2 10.0 1.2 1 0 0 1 1 1 0 Tropomyosin HemX PF04375.14 EAX89047.1 - 0.028 13.7 6.6 0.041 13.2 6.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 EAX89047.1 - 0.04 14.2 3.5 0.085 13.1 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FapA PF03961.13 EAX89047.1 - 0.04 12.5 16.0 0.023 13.3 13.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EAX89047.1 - 0.053 11.4 9.4 0.068 11.1 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 EAX89047.1 - 0.059 13.2 11.8 0.052 13.4 10.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Halogen_Hydrol PF10112.9 EAX89047.1 - 0.061 13.3 3.4 0.11 12.5 3.4 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Phage_GPO PF05929.11 EAX89047.1 - 0.064 12.9 4.3 0.13 11.9 4.3 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Vps4_C PF09336.10 EAX89047.1 - 0.068 13.2 0.2 0.31 11.1 0.0 2.2 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain Occludin_ELL PF07303.13 EAX89047.1 - 0.07 13.9 9.2 0.31 11.8 1.5 2.7 1 1 1 2 2 2 0 Occludin homology domain TMPIT PF07851.13 EAX89047.1 - 0.085 12.1 9.7 0.15 11.3 9.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EAX89047.1 - 0.087 12.2 3.0 0.13 11.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCPsignal PF00015.21 EAX89047.1 - 0.098 12.5 5.1 0.24 11.2 5.1 1.7 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Jnk-SapK_ap_N PF09744.9 EAX89047.1 - 0.11 12.7 9.6 0.23 11.7 9.6 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 EAX89047.1 - 0.12 11.8 12.2 0.21 11.0 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Med4 PF10018.9 EAX89047.1 - 0.13 11.9 6.7 0.2 11.3 6.7 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.8 EAX89047.1 - 0.14 12.2 25.0 0.3 11.1 25.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.6 EAX89047.1 - 0.15 12.1 7.7 0.12 12.5 5.6 1.7 2 0 0 2 2 1 0 Nucleoporin complex subunit 54 KELK PF15796.5 EAX89047.1 - 0.15 12.5 10.1 0.39 11.2 10.1 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_11 PF13086.6 EAX89047.1 - 0.23 11.2 8.4 0.6 9.9 7.1 2.1 2 0 0 2 2 2 0 AAA domain DUF1147 PF06615.11 EAX89047.1 - 0.27 11.3 1.2 2.6e+02 1.8 0.0 4.7 6 0 0 6 6 4 0 Protein of unknown function (DUF1147) WXG100 PF06013.12 EAX89047.1 - 0.36 11.1 7.5 17 5.7 6.8 2.8 2 1 0 2 2 1 0 Proteins of 100 residues with WXG DUF745 PF05335.13 EAX89047.1 - 0.46 10.2 7.1 0.88 9.3 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec34 PF04136.15 EAX89047.1 - 0.5 10.2 13.9 0.1 12.5 10.1 1.9 2 0 0 2 2 1 0 Sec34-like family HAUS6_N PF14661.6 EAX89047.1 - 0.53 9.8 8.2 0.96 9.0 8.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L30 PF00327.20 EAX89047.1 - 0.55 10.2 2.5 2e+02 2.0 0.0 4.8 6 0 0 6 6 3 0 Ribosomal protein L30p/L7e Syntaxin-6_N PF09177.11 EAX89047.1 - 0.62 10.6 6.9 0.85 10.2 5.2 2.0 2 0 0 2 2 1 0 Syntaxin 6, N-terminal Lip_prot_lig_C PF10437.9 EAX89047.1 - 0.62 10.1 9.9 0.28 11.2 0.3 3.3 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF2968 PF11180.8 EAX89047.1 - 0.65 9.6 10.0 1.1 8.8 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) YabA PF06156.13 EAX89047.1 - 0.72 10.5 8.4 2.3 8.9 8.4 1.9 1 0 0 1 1 1 0 Initiation control protein YabA GTP-bdg_M PF16360.5 EAX89047.1 - 0.72 10.5 7.3 9.1 7.0 1.9 2.9 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DUF4140 PF13600.6 EAX89047.1 - 0.81 10.2 5.6 0.99 9.9 4.4 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2203 PF09969.9 EAX89047.1 - 0.81 10.4 8.7 3 8.6 7.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ECH_2 PF16113.5 EAX89047.1 - 0.89 9.0 4.1 1.5 8.3 4.1 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF948 PF06103.11 EAX89047.1 - 1.1 9.6 7.4 1.9 8.8 5.8 2.3 1 1 1 2 2 1 0 Bacterial protein of unknown function (DUF948) E2F_CC-MB PF16421.5 EAX89047.1 - 1.2 9.6 9.3 4.6 7.7 9.1 2.2 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain DUF4200 PF13863.6 EAX89047.1 - 1.2 9.5 16.8 4.4 7.7 16.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2408 PF10303.9 EAX89047.1 - 1.3 9.5 14.0 3.4 8.2 13.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.12 EAX89047.1 - 1.5 9.3 11.7 38 4.8 11.7 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MCU PF04678.13 EAX89047.1 - 1.9 8.5 6.2 7.3 6.7 6.1 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Seryl_tRNA_N PF02403.22 EAX89047.1 - 2.2 8.6 18.3 4.3 7.6 17.5 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 EAX89047.1 - 2.3 8.1 17.0 1.8 8.5 3.8 3.6 2 1 1 3 3 3 0 Prefoldin subunit Vfa1 PF08432.10 EAX89047.1 - 2.6 8.4 10.6 4.7 7.5 10.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BLOC1_2 PF10046.9 EAX89047.1 - 4.2 7.7 17.6 14 6.1 10.1 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EAX89047.1 - 4.9 7.3 22.3 0.87 9.8 17.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sec20 PF03908.13 EAX89047.1 - 5.3 7.0 11.5 9.7 6.2 2.4 2.9 1 1 1 2 2 2 0 Sec20 UPF0184 PF03670.13 EAX89047.1 - 5.8 7.4 13.0 2.1 8.8 6.4 3.1 3 1 1 4 4 3 0 Uncharacterised protein family (UPF0184) DUF4404 PF14357.6 EAX89047.1 - 6.2 7.5 11.0 27 5.5 2.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) PI_PP_I PF18363.1 EAX89047.1 - 6.4 7.0 8.4 16 5.7 8.1 1.9 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DSPc PF00782.20 EAX89047.1 - 6.5 6.6 8.9 15 5.4 0.0 2.8 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain Allexi_40kDa PF05549.11 EAX89047.1 - 9.2 5.7 9.7 8.1 5.9 4.1 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Inositol_P PF00459.25 EAX89048.1 - 2.8e-52 177.9 0.0 3.4e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EAX89048.1 - 0.00028 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Ribosomal_L1 PF00687.21 EAX89049.1 - 1.1e-33 116.7 4.4 1.3e-33 116.4 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Sec10 PF07393.11 EAX89049.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Rad51 PF08423.11 EAX89051.1 - 1e-23 84.0 0.0 1.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 EAX89051.1 - 2.5e-06 27.0 0.0 5.3e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 KaiC Adeno_IVa2 PF02456.15 EAX89051.1 - 0.00025 20.0 0.0 0.00042 19.2 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA PF00004.29 EAX89051.1 - 0.001 19.5 0.0 0.0048 17.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX89051.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EAX89051.1 - 0.068 12.6 0.0 0.34 10.3 0.0 1.9 1 1 0 1 1 1 0 recA bacterial DNA recombination protein RNA_helicase PF00910.22 EAX89051.1 - 0.081 13.3 0.1 0.58 10.6 0.0 2.4 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 EAX89051.1 - 0.093 11.8 0.0 0.24 10.4 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EAX89051.1 - 0.13 12.8 0.0 0.51 10.9 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 EAX89051.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EAX89051.1 - 0.18 12.1 0.0 1.8 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Inositol_P PF00459.25 EAX89052.1 - 7.5e-26 91.2 0.0 1.9e-25 89.9 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family SurE PF01975.17 EAX89053.1 - 4.2e-51 173.5 0.0 5.2e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF374 PF04028.13 EAX89053.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) DUF4108 PF13390.6 EAX89054.1 - 9.2e-70 233.1 12.4 1.1e-69 232.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX89055.1 - 0.0043 16.7 5.5 0.018 14.6 5.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAX89055.1 - 3.3 8.1 7.4 8.9 6.8 1.3 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX89056.1 - 0.022 15.2 0.6 0.046 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX89057.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89058.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ras PF00071.22 EAX89059.1 - 2.7e-53 179.9 0.0 3.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89059.1 - 3e-22 79.1 0.0 4.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89059.1 - 6.9e-08 32.1 0.0 1.1e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX89059.1 - 0.051 12.9 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX89059.1 - 0.14 11.7 0.5 0.25 10.9 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ubiquitin PF00240.23 EAX89061.1 - 4.7e-12 45.5 0.1 8.9e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX89061.1 - 0.0002 21.1 0.1 0.00049 19.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX89061.1 - 0.0028 18.0 0.0 0.0076 16.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain SPACA7 PF15307.6 EAX89061.1 - 0.034 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 TBK1_ULD PF18396.1 EAX89061.1 - 0.044 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain TPR_MLP1_2 PF07926.12 EAX89063.1 - 0.015 15.3 7.0 0.019 15.0 7.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EAX89063.1 - 0.029 13.3 8.4 0.031 13.2 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF745 PF05335.13 EAX89063.1 - 0.031 14.0 0.8 0.04 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CAF-1_p150 PF11600.8 EAX89063.1 - 0.05 13.3 8.4 0.05 13.3 8.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal E2F_CC-MB PF16421.5 EAX89063.1 - 0.062 13.7 3.3 0.071 13.5 2.6 1.3 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain Cortex-I_coil PF09304.10 EAX89063.1 - 0.089 13.0 7.4 0.097 12.9 7.4 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil ACCA PF03255.14 EAX89063.1 - 0.17 11.8 4.7 0.18 11.6 4.7 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fmp27_WPPW PF10359.9 EAX89063.1 - 0.22 10.3 6.3 0.25 10.2 6.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1840 PF08895.11 EAX89063.1 - 0.31 11.4 4.4 0.39 11.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FlxA PF14282.6 EAX89063.1 - 0.32 11.0 9.6 2.4 8.2 9.6 2.0 1 1 0 1 1 1 0 FlxA-like protein DUF1811 PF08838.10 EAX89063.1 - 0.33 11.2 5.4 0.63 10.3 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1811) TMPIT PF07851.13 EAX89063.1 - 0.66 9.2 4.7 0.69 9.1 4.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EAX89063.1 - 0.72 9.9 5.0 0.97 9.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) eIF-4B PF06273.11 EAX89063.1 - 2.5 7.1 7.5 2.6 7.0 7.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B WD40 PF00400.32 EAX89064.1 - 8e-16 58.2 4.0 0.00021 22.0 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX89064.1 - 2.5e-08 34.1 0.5 0.01 16.1 0.0 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX89064.1 - 7.9e-06 25.4 7.2 0.0012 18.3 2.4 2.2 1 1 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 EAX89064.1 - 0.0016 17.0 0.2 0.012 14.2 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 EAX89064.1 - 0.22 12.0 0.9 4.7 7.8 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain PSP PF04046.16 EAX89065.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89066.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX89067.1 - 0.022 15.2 0.6 0.046 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89068.1 - 1.2e-05 25.3 4.6 3.4e-05 23.8 0.6 3.7 3 0 0 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX89068.1 - 0.032 13.9 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX89068.1 - 0.046 14.2 1.9 0.19 12.2 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX89068.1 - 0.94 9.2 9.6 0.95 9.2 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4795 PF16043.5 EAX89068.1 - 3.3 7.3 21.5 4.9e+02 0.2 21.5 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX89070.1 - 5.6e-149 494.2 10.3 7.3e-149 493.8 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX89070.1 - 0.013 15.9 0.5 0.076 13.5 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX89070.1 - 0.04 14.4 3.0 1.8 9.0 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX89070.1 - 0.04 14.3 0.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function ResIII PF04851.15 EAX89071.1 - 3.7e-20 72.6 0.0 3.7e-20 72.6 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89071.1 - 1.2e-19 70.8 0.0 1e-18 67.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX89071.1 - 1e-18 67.7 2.2 8.7e-18 64.7 0.2 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAX89071.1 - 0.0046 17.2 0.1 0.039 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EAX89071.1 - 0.045 13.2 0.0 5.8 6.3 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein DUF2026 PF09641.10 EAX89072.1 - 0.31 10.6 4.1 0.17 11.5 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) Ank PF00023.30 EAX89073.1 - 1.7e-178 572.1 85.3 3.6e-09 36.6 0.7 26.1 26 0 0 26 26 26 24 Ankyrin repeat Ank_2 PF12796.7 EAX89073.1 - 1.2e-168 548.2 112.0 1.2e-20 73.8 1.3 14.6 4 4 11 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89073.1 - 1.1e-157 510.6 61.4 2.3e-13 50.4 1.1 22.8 6 2 19 25 25 25 23 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89073.1 - 7.8e-127 411.7 56.5 2.9e-11 43.4 0.9 17.9 7 4 11 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89073.1 - 4.4e-122 383.0 75.7 4.7e-06 26.5 0.3 27.5 29 0 0 29 29 29 24 Ankyrin repeat DUF3447 PF11929.8 EAX89073.1 - 1.6e-31 108.1 1.3 1.6e-31 108.1 1.3 10.4 7 2 4 12 12 12 1 Domain of unknown function (DUF3447) WPP PF13943.6 EAX89073.1 - 0.14 12.6 0.1 22 5.5 0.0 4.4 5 0 0 5 5 5 0 WPP domain Arylsulfotran_N PF17425.2 EAX89074.1 - 0.038 14.0 2.0 0.35 10.9 1.8 2.6 2 0 0 2 2 2 0 Arylsulfotransferase Ig-like domain Pkinase PF00069.25 EAX89075.1 - 1.3e-34 119.8 0.2 1.6e-34 119.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89075.1 - 1.4e-17 63.8 0.1 2.1e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C14 PF00656.22 EAX89076.1 - 2.7e-11 43.9 3.7 4.4e-09 36.7 3.7 2.1 1 1 0 1 1 1 1 Caspase domain IL3Ra_N PF18611.1 EAX89076.1 - 0.054 13.5 12.3 0.15 12.1 4.7 2.9 2 1 1 3 3 3 0 IL-3 receptor alpha chain N-terminal domain DUF4718 PF15842.5 EAX89076.1 - 0.063 13.1 3.2 6.7 6.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4718) Ank_2 PF12796.7 EAX89078.1 - 3.4e-19 69.2 0.5 4.9e-09 36.6 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89078.1 - 8.5e-13 47.3 7.9 0.017 15.6 0.1 7.7 8 1 1 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 EAX89078.1 - 2.5e-11 43.8 2.8 5.2e-05 23.7 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89078.1 - 3.3e-10 40.0 0.6 0.0011 19.2 0.0 4.0 2 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX89078.1 - 6.3e-07 29.6 2.3 0.32 11.5 0.0 5.3 4 1 1 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX89078.1 - 1.1e-05 25.3 11.8 0.00018 21.4 1.5 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89079.1 - 1.9e-46 156.6 0.6 6.1e-23 81.2 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89079.1 - 1.3e-18 67.1 0.0 3.3e-08 33.9 0.0 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89079.1 - 1.8e-17 63.2 0.0 7.3e-07 29.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX89079.1 - 9.7e-16 57.4 0.0 0.00023 21.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX89079.1 - 1.2e-14 53.0 0.0 0.00055 20.2 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat APG6_N PF17675.1 EAX89079.1 - 0.02 15.4 0.4 0.042 14.4 0.2 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 EAX89079.1 - 0.031 14.6 0.6 0.058 13.7 0.6 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Adenine_glyco PF03352.13 EAX89079.1 - 0.049 13.4 2.0 0.076 12.8 2.0 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase Vps54 PF07928.12 EAX89079.1 - 0.062 13.7 0.6 0.12 12.8 0.6 1.5 1 0 0 1 1 1 0 Vps54-like protein DUF2730 PF10805.8 EAX89079.1 - 0.082 13.0 0.7 0.17 12.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Pox_A_type_inc PF04508.12 EAX89081.1 - 0.0041 16.9 0.4 0.028 14.3 0.4 2.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat PYST-C1 PF09690.10 EAX89081.1 - 0.0053 16.5 3.7 0.0053 16.5 3.7 2.8 3 0 0 3 3 3 1 Plasmodium yoelii subtelomeric region (PYST-C1) Amidase02_C PF12123.8 EAX89081.1 - 0.18 11.6 0.8 9 6.1 0.1 2.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF2203 PF09969.9 EAX89081.1 - 0.4 11.4 23.7 6.8 7.4 3.8 4.4 2 2 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF3492 PF11997.8 EAX89081.1 - 1.1 9.0 4.6 0.35 10.6 0.1 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF3492) TPR_MLP1_2 PF07926.12 EAX89081.1 - 1.7 8.7 34.7 1.3 9.0 11.3 4.1 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein HU-CCDC81_bac_2 PF18175.1 EAX89081.1 - 2.7 7.9 6.0 5.8 6.9 0.1 3.6 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 YpjP PF14005.6 EAX89082.1 - 0.54 10.3 5.4 0.33 11.0 0.6 2.9 2 2 0 2 2 2 0 YpjP-like protein Ras PF00071.22 EAX89083.1 - 1.3e-36 125.7 0.0 1.5e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89083.1 - 3.4e-27 95.1 0.0 4.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89083.1 - 2.5e-14 53.1 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX89083.1 - 9.9e-08 32.1 0.1 1.7e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX89083.1 - 2.1e-05 24.2 0.1 0.00011 21.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX89083.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX89083.1 - 0.0022 17.4 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX89083.1 - 0.0027 17.6 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 EAX89083.1 - 0.0099 15.3 0.1 0.03 13.7 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein PduV-EutP PF10662.9 EAX89083.1 - 0.033 13.9 0.1 0.19 11.5 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX89083.1 - 0.11 12.1 0.6 0.27 10.8 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PSP PF04046.16 EAX89085.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89086.1 - 0.019 15.4 2.6 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Myc_N PF01056.18 EAX89088.1 - 0.02 14.8 1.0 0.02 14.8 1.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EAX89088.1 - 0.11 11.8 1.6 0.12 11.7 1.6 1.2 1 0 0 1 1 1 0 NOA36 protein EP400_N PF15790.5 EAX89088.1 - 0.26 10.1 1.1 0.26 10.1 1.1 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal 3Beta_HSD PF01073.19 EAX89091.1 - 1.4e-15 57.1 0.5 2.2e-15 56.4 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAX89091.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAX89091.1 - 4.3e-10 39.8 0.1 7.7e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EAX89091.1 - 1.6e-08 34.1 0.1 4.1e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EAX89091.1 - 3.4e-08 33.3 0.0 6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EAX89091.1 - 2.3e-07 30.3 0.2 1.7e-06 27.4 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein DUF4379 PF14311.6 EAX89091.1 - 0.00045 20.5 3.7 0.0011 19.3 3.7 1.7 1 0 0 1 1 1 1 Probable Zinc-ribbon domain adh_short PF00106.25 EAX89091.1 - 0.00047 19.7 0.1 0.0015 18.1 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EAX89091.1 - 0.0016 18.0 0.1 0.0023 17.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 EAX89091.1 - 0.053 14.2 0.1 0.084 13.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 EAX89092.1 - 1.5e-15 57.0 0.5 2.3e-15 56.3 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAX89092.1 - 2e-13 50.4 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAX89092.1 - 3e-10 40.3 0.0 8.2e-10 38.9 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EAX89092.1 - 1.6e-08 34.0 0.1 4.3e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EAX89092.1 - 2.9e-08 33.5 0.0 6.4e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EAX89092.1 - 3.2e-07 29.8 0.2 1.8e-06 27.3 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein DUF4379 PF14311.6 EAX89092.1 - 0.00048 20.4 3.7 0.0012 19.2 3.7 1.6 1 0 0 1 1 1 1 Probable Zinc-ribbon domain adh_short PF00106.25 EAX89092.1 - 0.00049 19.6 0.1 0.0015 18.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EAX89092.1 - 0.0017 18.0 0.1 0.0025 17.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 EAX89092.1 - 0.054 14.2 0.1 0.088 13.5 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PSP PF04046.16 EAX89093.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89094.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX89096.1 - 2.2e-23 82.1 11.1 2.2e-23 82.1 11.1 3.7 4 1 0 4 4 4 1 Phage tail repeat like DUF3839 PF12943.7 EAX89097.1 - 3.1e-156 518.0 13.8 3.8e-156 517.7 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX89097.1 - 0.061 13.6 0.6 1.4 9.2 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX89097.1 - 0.16 11.9 1.3 0.48 10.3 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX89097.1 - 0.22 12.1 4.3 0.52 10.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX89097.1 - 0.46 11.0 5.6 5.2 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX89098.1 - 5.8e-18 65.7 14.5 4.2e-11 43.2 11.5 2.0 1 1 1 2 2 2 2 Glycine rich protein LRR_5 PF13306.6 EAX89099.1 - 2.3e-69 231.3 27.3 1.9e-31 108.7 0.0 4.6 3 1 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89099.1 - 1.3e-11 44.0 7.3 1.6e-05 24.6 0.0 5.3 4 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EAX89099.1 - 0.00027 21.3 9.5 0.33 11.4 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX89100.1 - 1.3e-50 170.6 40.8 4.7e-18 65.4 15.2 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89100.1 - 3.8e-10 39.4 1.6 0.00039 20.1 0.0 5.4 3 1 2 6 6 6 3 Leucine rich repeat Gly_rich PF12810.7 EAX89101.1 - 2.3e-44 152.2 23.3 2.6e-44 152.0 23.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX89102.1 - 4.9e-61 206.7 31.0 5.9e-61 206.5 31.0 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX89103.1 - 3.5e-83 275.9 79.3 1.4e-25 89.8 1.1 5.3 1 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89103.1 - 3.6e-10 39.4 5.7 0.65 9.8 0.0 7.1 6 1 2 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAX89103.1 - 0.0073 16.7 11.7 0.33 11.5 0.1 6.6 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX89104.1 - 2.5e-15 56.5 6.0 5.6e-09 36.0 0.8 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89104.1 - 0.0066 16.2 1.6 0.73 9.6 0.4 3.3 1 1 3 4 4 4 2 Leucine rich repeat SAM_Ste50p PF09235.10 EAX89104.1 - 0.014 15.6 2.5 0.04 14.1 1.3 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Gly_rich PF12810.7 EAX89105.1 - 2.8e-62 210.8 35.0 3.4e-62 210.5 35.0 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX89106.1 - 2e-21 76.3 8.9 4e-16 59.2 3.3 2.1 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89106.1 - 0.00025 20.7 0.0 0.0028 17.4 0.0 2.5 2 1 1 3 3 3 2 Leucine rich repeat Gly_rich PF12810.7 EAX89107.1 - 5.9e-41 141.0 20.9 7e-41 140.7 20.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Malic_M PF03949.15 EAX89108.1 - 2.1e-18 66.6 1.7 3.8e-17 62.4 1.7 2.0 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 EAX89108.1 - 0.049 12.9 0.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain C2 PF00168.30 EAX89111.1 - 0.029 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 C2 domain Malic_M PF03949.15 EAX89112.1 - 3.9e-30 105.0 6.9 4.5e-29 101.5 6.9 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAX89112.1 - 1.5e-29 103.0 0.1 1.8e-26 93.1 0.1 2.8 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain ELFV_dehydrog PF00208.21 EAX89112.1 - 0.00019 21.2 0.2 0.00035 20.4 0.2 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EAX89112.1 - 0.0005 19.4 2.4 0.00093 18.5 2.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EAX89112.1 - 0.022 14.2 0.1 0.047 13.0 0.1 1.6 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 EAX89112.1 - 0.082 13.2 0.8 0.3 11.3 0.3 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LCM PF04072.14 EAX89113.1 - 1.1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Pkinase PF00069.25 EAX89114.1 - 1.4e-21 77.1 1.4 1e-18 67.7 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89114.1 - 6.1e-14 51.9 0.7 2.3e-10 40.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EAX89114.1 - 9.7e-07 28.9 0.3 0.00093 19.2 0.1 3.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family DUF4710 PF15828.5 EAX89114.1 - 0.0031 17.6 3.1 0.012 15.7 3.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4710) Vps23_core PF09454.10 EAX89114.1 - 0.075 13.0 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Vps23 core domain FAM176 PF14851.6 EAX89114.1 - 0.83 9.3 4.6 1.9 8.2 4.6 1.5 1 0 0 1 1 1 0 FAM176 family RRP14 PF15459.6 EAX89114.1 - 4.9 7.8 8.4 0.38 11.4 2.2 2.4 2 1 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Eaf7 PF07904.13 EAX89114.1 - 5.3 7.5 9.3 3.5 8.0 4.4 2.9 1 1 0 2 2 2 0 Chromatin modification-related protein EAF7 RPA43_OB PF17875.1 EAX89114.1 - 9.3 6.9 7.0 47 4.6 7.0 2.2 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I CRPA PF05745.11 EAX89115.1 - 0.11 12.6 0.6 0.16 12.0 0.6 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) SOG2 PF10428.9 EAX89115.1 - 0.11 11.7 7.9 0.12 11.6 7.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein UL45 PF05473.12 EAX89115.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PsbX PF06596.11 EAX89115.1 - 0.13 12.3 4.9 0.27 11.3 4.9 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Rib_recp_KP_reg PF05104.12 EAX89115.1 - 9.3 7.3 10.6 14 6.7 10.6 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pkinase PF00069.25 EAX89116.1 - 5.9e-61 206.1 0.1 5.4e-60 203.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89116.1 - 1.3e-29 103.3 0.1 2e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAX89116.1 - 1.9e-05 24.1 0.5 0.0074 15.6 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EAX89116.1 - 6.3e-05 23.0 0.1 0.00031 20.8 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX89116.1 - 0.00017 20.6 0.9 0.00029 19.9 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX89116.1 - 0.00045 19.1 0.1 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_C PF00433.24 EAX89116.1 - 0.008 16.9 0.4 0.031 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Ank_4 PF13637.6 EAX89118.1 - 3.5e-21 75.3 0.2 2.3e-09 37.6 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX89118.1 - 4.4e-20 71.2 0.8 2.2e-08 34.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX89118.1 - 3.8e-19 68.5 0.6 2.2e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89118.1 - 8.8e-19 67.9 2.9 2.7e-09 37.5 0.9 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89118.1 - 6.2e-15 53.8 0.4 8.7e-06 25.7 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeat Flu_B_M2 PF04772.12 EAX89118.1 - 0.0038 17.4 0.1 0.0047 17.1 0.1 1.1 1 0 0 1 1 1 1 Influenza B matrix protein 2 (BM2) TolA PF06519.11 EAX89118.1 - 0.084 13.1 0.1 7.1 6.9 0.0 2.0 1 1 1 2 2 2 0 TolA C-terminal DUF3447 PF11929.8 EAX89119.1 - 4.1e-38 129.2 6.7 4.1e-38 129.2 6.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX89119.1 - 9.1e-35 118.6 4.1 3.6e-09 37.0 0.0 6.5 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89119.1 - 2.2e-33 114.7 13.5 6.3e-15 55.5 2.7 4.2 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89119.1 - 5.4e-33 112.0 1.9 1.7e-06 28.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX89119.1 - 2.7e-28 94.9 2.1 4.2e-05 23.6 0.0 7.3 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX89119.1 - 4.2e-22 77.9 4.7 3e-09 37.0 0.4 4.3 3 1 0 4 4 4 2 Ankyrin repeats (many copies) PrpR_N PF06506.11 EAX89119.1 - 0.00022 20.9 3.8 4.2 6.9 0.1 4.8 2 1 3 5 5 5 2 Propionate catabolism activator MetallophosN PF16371.5 EAX89119.1 - 0.026 14.8 0.2 11 6.3 0.1 3.7 1 1 1 3 3 3 0 N terminal of Calcineurin-like phosphoesterase DHBP_synthase PF00926.19 EAX89119.1 - 0.061 12.8 1.9 36 3.8 0.0 3.4 1 1 3 4 4 4 0 3,4-dihydroxy-2-butanone 4-phosphate synthase CinA_KH PF18146.1 EAX89119.1 - 0.1 12.8 4.7 27 5.0 0.1 3.8 1 1 3 4 4 4 0 Damage-inducible protein CinA KH domain rve_2 PF13333.6 EAX89120.1 - 0.059 13.6 2.9 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain DUF3839 PF12943.7 EAX89121.1 - 4.4e-114 380.0 6.9 5.1e-114 379.7 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89121.1 - 0.25 11.8 1.4 0.53 10.8 0.3 2.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAX89122.1 - 1.8e-61 207.8 1.6 2.5e-61 207.4 1.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89122.1 - 7e-43 146.8 0.4 8.4e-43 146.5 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89122.1 - 5.6e-07 29.2 1.4 0.01 15.2 0.1 2.8 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAX89122.1 - 2.5e-06 26.6 0.0 4.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX89122.1 - 6e-05 22.7 2.5 0.002 17.8 0.3 2.5 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 EAX89122.1 - 0.00017 21.0 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX89122.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX89122.1 - 0.00065 19.4 0.2 0.0012 18.5 0.1 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAX89122.1 - 0.0016 18.0 1.2 0.0023 17.6 0.4 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EAX89122.1 - 0.0025 16.8 1.0 0.0064 15.5 1.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Ribosomal_L7Ae PF01248.26 EAX89122.1 - 0.013 15.2 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PIP49_C PF12260.8 EAX89122.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF5099 PF17025.5 EAX89122.1 - 0.25 11.8 3.3 0.14 12.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) Pkinase PF00069.25 EAX89123.1 - 7.6e-63 212.3 0.1 1.1e-62 211.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89123.1 - 1.5e-37 129.3 0.0 1.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89123.1 - 8.6e-06 25.3 0.0 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX89123.1 - 3.4e-05 23.9 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX89123.1 - 0.00095 18.0 0.0 0.002 17.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase DUF1938 PF09153.10 EAX89123.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1938) Kdo PF06293.14 EAX89123.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX89123.1 - 0.027 13.4 0.2 0.053 12.5 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EAX89123.1 - 0.028 14.0 0.1 0.18 11.4 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.20 EAX89123.1 - 0.033 13.8 0.2 0.14 11.7 0.1 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAX89124.1 - 5.5e-63 212.8 0.0 7.8e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89124.1 - 2.8e-38 131.7 0.0 3.3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89124.1 - 1.3e-05 24.7 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX89124.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX89124.1 - 0.0016 17.3 0.0 0.0031 16.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EAX89124.1 - 0.0023 16.9 0.1 0.0036 16.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EAX89124.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX89124.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 EAX89125.1 - 9.3e-27 93.4 0.2 6.5e-10 39.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89125.1 - 2.7e-19 69.0 0.0 8.3e-07 29.2 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89125.1 - 8e-17 61.4 0.1 1.1e-05 25.8 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89125.1 - 5e-12 45.7 0.0 7.3e-07 29.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX89125.1 - 1.1e-11 43.8 0.0 0.0013 19.0 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Guanylate_cyc PF00211.20 EAX89126.1 - 5e-28 98.0 0.0 5.7e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4869 PF16163.5 EAX89127.1 - 0.024 14.3 0.7 0.024 14.3 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4869) TPR_17 PF13431.6 EAX89127.1 - 0.037 14.4 0.5 0.11 12.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 EAX89127.1 - 0.11 12.4 0.1 0.73 9.8 0.0 2.3 3 0 0 3 3 3 0 AhpC/TSA family DUF4107 PF13389.6 EAX89128.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX89128.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX89129.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Myb_DNA-binding PF00249.31 EAX89130.1 - 2.6e-29 101.2 5.3 4.9e-16 58.6 1.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89130.1 - 1.8e-24 85.7 7.3 8.9e-18 64.3 1.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89130.1 - 7.7e-06 25.7 0.6 0.01 15.7 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX89130.1 - 6.1e-05 23.0 0.1 0.27 11.3 0.0 2.4 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX89130.1 - 0.00071 19.6 0.3 1.4 9.0 0.1 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX89130.1 - 0.39 11.1 3.3 3 8.3 0.2 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX89131.1 - 1.8e-31 108.1 4.5 1.8e-15 56.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89131.1 - 2.6e-28 98.0 6.1 1.6e-16 60.3 0.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89131.1 - 2.3e-06 27.6 0.2 0.01 15.9 0.1 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX89131.1 - 5.3e-05 23.0 1.6 0.17 11.8 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX89131.1 - 0.00085 19.6 8.5 0.012 16.0 2.3 3.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EAX89131.1 - 0.0069 16.4 2.1 0.38 10.9 0.1 3.0 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX89131.1 - 0.01 16.1 3.8 0.32 11.4 0.7 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF722 PF05263.11 EAX89131.1 - 0.045 14.0 0.7 0.19 12.0 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF722) CBM65_1 PF18259.1 EAX89131.1 - 0.05 13.8 0.7 0.12 12.5 0.6 1.8 1 1 0 1 1 1 0 Carbohydrate binding module 65 domain 1 Atg29_N PF18388.1 EAX89131.1 - 0.07 13.0 2.2 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain YbbR PF07949.12 EAX89132.1 - 0.047 14.0 2.8 0.63 10.4 0.2 2.7 1 1 1 2 2 2 0 YbbR-like protein Ras PF00071.22 EAX89133.1 - 6.5e-41 139.6 0.1 7.7e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89133.1 - 2.6e-29 101.9 0.0 4e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89133.1 - 2.2e-15 56.5 0.0 2.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX89133.1 - 3.3e-05 23.5 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX89133.1 - 0.00097 18.6 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX89133.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3966 PF13110.6 EAX89133.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) NAD_binding_9 PF13454.6 EAX89135.1 - 4.3e-22 78.8 0.0 5.2e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding PSP PF04046.16 EAX89136.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89137.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX89138.1 - 0.033 14.6 0.8 0.067 13.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89139.1 - 4.8e-30 103.4 10.9 4.8e-30 103.4 10.9 4.5 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX89139.1 - 0.065 13.0 0.2 0.39 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX89139.1 - 0.87 9.5 6.4 1.6 8.7 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF240) TbpB_A PF17484.2 EAX89139.1 - 1 10.1 9.6 0.78 10.5 5.6 2.6 2 2 0 2 2 2 0 N-Lobe handle Tf-binding protein B MULE PF10551.9 EAX89141.1 - 1e-10 41.9 0.2 2.5e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX89141.1 - 0.024 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DpnD-PcfM PF14207.6 EAX89142.1 - 0.0062 16.4 1.6 1.1e+02 2.8 0.0 5.7 7 0 0 7 7 7 0 DpnD/PcfM-like protein Transketolase_C PF02780.20 EAX89142.1 - 0.018 14.9 2.6 3.4 7.5 0.1 3.9 1 1 3 5 5 5 0 Transketolase, C-terminal domain DUF4090 PF13319.6 EAX89142.1 - 0.023 14.9 0.4 34 4.8 0.0 4.1 2 2 3 5 5 5 0 Protein of unknown function (DUF4090) SQS_PSY PF00494.19 EAX89142.1 - 0.098 12.1 1.0 3.6 7.0 0.0 2.5 1 1 1 2 2 2 0 Squalene/phytoene synthase RNA_pol_Rpc4 PF05132.14 EAX89142.1 - 0.24 11.8 0.0 29 5.1 0.0 3.1 2 1 0 2 2 2 0 RNA polymerase III RPC4 Acetyltransf_7 PF13508.7 EAX89142.1 - 4 7.9 9.2 6.1e+02 0.9 9.2 3.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DDE_1 PF03184.19 EAX89143.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EAX89145.1 - 0.0017 18.1 0.0 0.0021 17.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.9 EAX89146.1 - 1.1e-13 51.4 0.2 2.3e-13 50.4 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX89146.1 - 0.15 11.8 4.6 0.23 11.1 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX89146.1 - 0.49 10.6 5.6 1.4 9.2 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX89146.1 - 1.2 8.9 5.3 1.9 8.2 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHR-2 PF06920.13 EAX89149.1 - 6.5e-13 48.2 0.7 1.1e-12 47.4 0.7 1.3 1 0 0 1 1 1 1 Dock homology region 2 ABC_tran PF00005.27 EAX89149.1 - 0.064 13.8 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter CCDC24 PF15669.5 EAX89150.1 - 4.8e-05 23.3 5.1 0.00074 19.4 3.9 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family LETM1 PF07766.13 EAX89150.1 - 0.2 11.0 4.7 0.13 11.6 0.6 2.0 2 0 0 2 2 2 0 LETM1-like protein Fib_alpha PF08702.10 EAX89150.1 - 0.21 11.8 7.9 0.073 13.3 1.5 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EAX89150.1 - 0.42 10.7 2.6 0.97 9.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EAX89150.1 - 0.47 10.5 4.0 1 9.4 0.2 2.6 1 1 0 2 2 2 0 Laminin Domain II TMPIT PF07851.13 EAX89150.1 - 2.8 7.1 5.4 2 7.6 1.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF5392 PF17370.2 EAX89151.1 - 0.061 13.4 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Prefoldin PF02996.17 EAX89152.1 - 4.9e-22 78.1 6.4 6.3e-22 77.7 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin_2 PF14523.6 EAX89152.1 - 0.0031 17.8 2.6 0.0031 17.8 2.6 2.3 2 1 0 2 2 2 2 Syntaxin-like protein DUF4407 PF14362.6 EAX89152.1 - 0.91 8.8 7.9 0.69 9.2 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 EAX89153.1 - 0.011 16.1 15.5 0.34 11.3 0.2 4.7 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Csm2_III-A PF03750.13 EAX89153.1 - 0.059 14.2 0.3 0.059 14.2 0.3 2.7 3 0 0 3 3 3 0 Csm2 Type III-A DUF948 PF06103.11 EAX89153.1 - 0.62 10.4 12.5 2.8 8.3 0.5 3.9 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3447 PF11929.8 EAX89154.1 - 2e-36 123.7 8.0 2e-36 123.7 8.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89154.1 - 4.3e-16 59.3 1.0 4.3e-10 40.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89154.1 - 3.5e-15 56.2 0.3 1.1e-07 32.3 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX89154.1 - 8.2e-11 41.8 0.4 7e-07 29.4 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 EAX89154.1 - 1.9e-09 37.0 0.5 4.9e-05 23.4 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EAX89154.1 - 3.7e-09 36.7 0.0 3.1e-07 30.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RL PF17797.1 EAX89154.1 - 0.065 13.2 6.0 0.31 11.0 0.5 3.8 4 1 1 5 5 5 0 RL domain ATP13 PF12921.7 EAX89154.1 - 0.074 12.9 0.3 0.57 10.1 0.6 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase expression Ank_2 PF12796.7 EAX89155.1 - 1.1e-50 170.1 7.9 5e-15 55.8 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89155.1 - 2.8e-35 119.2 0.4 5.1e-06 26.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX89155.1 - 2.3e-34 117.0 3.0 5e-11 42.6 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89155.1 - 2.9e-34 117.0 0.2 1.1e-10 41.8 0.0 4.2 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89155.1 - 3.9e-22 76.0 0.2 0.0036 17.7 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat ERM PF00769.19 EAX89155.1 - 0.0015 18.4 1.1 0.0025 17.7 1.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Dor1 PF04124.12 EAX89155.1 - 0.0046 15.7 2.2 0.0071 15.1 2.2 1.3 1 0 0 1 1 1 1 Dor1-like family DivIC PF04977.15 EAX89155.1 - 0.019 14.7 2.0 0.038 13.8 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Cauli_VI PF01693.16 EAX89155.1 - 0.035 14.4 0.1 20 5.6 0.0 3.3 4 0 0 4 4 2 0 Caulimovirus viroplasmin Xylo_C PF12529.8 EAX89155.1 - 0.035 13.7 2.0 0.066 12.8 2.0 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal FlxA PF14282.6 EAX89155.1 - 0.039 13.9 5.7 0.11 12.5 5.7 1.7 1 0 0 1 1 1 0 FlxA-like protein NAD_binding_5 PF07994.12 EAX89155.1 - 0.11 11.8 2.3 0.17 11.3 2.3 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase MerR-DNA-bind PF09278.11 EAX89155.1 - 0.14 12.7 1.2 0.26 11.9 1.2 1.3 1 0 0 1 1 1 0 MerR, DNA binding Phage_GP20 PF06810.11 EAX89155.1 - 1.3 8.8 11.1 0.96 9.2 7.8 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 EAX89155.1 - 2.8 8.3 6.5 2.9 8.3 3.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ank_2 PF12796.7 EAX89156.1 - 9.4e-51 170.3 7.8 4.3e-15 56.1 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89156.1 - 1.9e-35 119.8 0.4 4.7e-06 26.8 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX89156.1 - 1.5e-34 117.6 7.0 4.5e-11 42.8 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89156.1 - 4.2e-34 116.5 0.1 1e-10 41.9 0.0 4.2 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89156.1 - 2.7e-22 76.4 0.2 0.0033 17.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat ERM PF00769.19 EAX89156.1 - 0.0021 17.9 1.2 0.0036 17.1 1.2 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Dor1 PF04124.12 EAX89156.1 - 0.0044 15.7 2.3 0.0063 15.2 2.3 1.3 1 0 0 1 1 1 1 Dor1-like family DivIC PF04977.15 EAX89156.1 - 0.017 14.9 2.0 0.034 13.9 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Cauli_VI PF01693.16 EAX89156.1 - 0.031 14.6 0.1 18 5.7 0.0 3.3 4 0 0 4 4 3 0 Caulimovirus viroplasmin FlxA PF14282.6 EAX89156.1 - 0.04 13.9 5.7 0.1 12.6 5.7 1.6 1 0 0 1 1 1 0 FlxA-like protein Xylo_C PF12529.8 EAX89156.1 - 0.077 12.6 1.1 0.14 11.7 1.1 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal MerR-DNA-bind PF09278.11 EAX89156.1 - 0.13 12.8 1.2 0.24 12.0 1.2 1.3 1 0 0 1 1 1 0 MerR, DNA binding Phage_GP20 PF06810.11 EAX89156.1 - 1.3 8.9 11.3 0.73 9.6 7.4 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 EAX89156.1 - 3.1 8.2 6.9 3.3 8.1 3.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ank_2 PF12796.7 EAX89157.1 - 3.7e-32 110.7 1.3 3.5e-15 56.4 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89157.1 - 5.1e-27 93.1 0.2 4e-06 27.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX89157.1 - 9e-27 92.8 2.3 3.7e-11 43.0 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89157.1 - 5.8e-24 84.1 0.1 1.2e-10 41.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89157.1 - 7.2e-18 62.8 0.2 0.0028 18.0 0.0 5.3 6 0 0 6 6 5 4 Ankyrin repeat ERM PF00769.19 EAX89157.1 - 0.0012 18.8 1.1 0.0019 18.1 1.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Dor1 PF04124.12 EAX89157.1 - 0.0038 16.0 2.5 0.0058 15.4 2.5 1.3 1 0 0 1 1 1 1 Dor1-like family DivIC PF04977.15 EAX89157.1 - 0.014 15.1 2.0 0.029 14.1 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Xylo_C PF12529.8 EAX89157.1 - 0.027 14.1 2.0 0.045 13.4 2.0 1.3 1 0 0 1 1 1 0 Xylosyltransferase C terminal FlxA PF14282.6 EAX89157.1 - 0.03 14.3 5.7 0.087 12.8 5.7 1.7 1 0 0 1 1 1 0 FlxA-like protein NAD_binding_5 PF07994.12 EAX89157.1 - 0.068 12.5 2.0 0.092 12.1 2.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase MerR-DNA-bind PF09278.11 EAX89157.1 - 0.11 13.0 1.2 0.2 12.2 1.2 1.3 1 0 0 1 1 1 0 MerR, DNA binding HARE-HTH PF05066.13 EAX89157.1 - 0.32 11.4 1.7 0.84 10.1 0.0 2.6 3 0 0 3 3 2 0 HB1, ASXL, restriction endonuclease HTH domain CCDC-167 PF15188.6 EAX89157.1 - 2.4 8.6 6.9 2.3 8.6 3.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 T5orf172 PF10544.9 EAX89158.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Cons_hypoth698 PF03601.14 EAX89159.1 - 0.074 11.9 0.4 0.14 11.0 0.4 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MFS_1 PF07690.16 EAX89160.1 - 5.5e-36 124.2 23.3 8e-33 113.8 25.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAX89160.1 - 1.7e-09 37.0 27.3 5.3e-06 25.6 9.1 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EAX89160.1 - 0.013 14.0 0.1 0.013 14.0 0.1 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector FAM209 PF15206.6 EAX89160.1 - 0.022 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 FAM209 family EF1G PF00647.19 EAX89161.1 - 0.012 15.7 1.3 0.033 14.2 1.3 1.9 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Cnn_1N PF07989.11 EAX89161.1 - 0.014 15.5 5.9 0.014 15.5 5.9 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 EAX89161.1 - 0.077 13.6 6.6 0.38 11.4 0.3 3.2 2 1 1 3 3 3 0 SlyX DivIC PF04977.15 EAX89161.1 - 2.7 7.8 11.4 5.8 6.8 0.9 3.4 2 1 1 3 3 3 0 Septum formation initiator TSC22 PF01166.18 EAX89161.1 - 5.4 7.4 9.4 2.8 8.3 0.4 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family Maf PF02545.14 EAX89162.1 - 3e-28 98.8 0.1 3.4e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein DUF1186 PF06685.11 EAX89162.1 - 0.1 11.9 0.1 0.59 9.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1186) Daxx PF03344.15 EAX89163.1 - 0.00022 21.2 2.1 0.11 12.5 0.1 3.1 2 0 0 2 2 2 2 Daxx N-terminal Rassf1C-interacting domain Csm1_N PF18504.1 EAX89163.1 - 0.011 16.1 0.7 0.011 16.1 0.7 9.6 7 2 4 11 11 11 0 Csm1 N-terminal domain T2SSF PF00482.23 EAX89163.1 - 0.44 10.5 9.8 5.9 6.9 0.0 4.2 5 0 0 5 5 5 0 Type II secretion system (T2SS), protein F DIMCO_N PF16844.5 EAX89163.1 - 5.9 7.3 14.2 0.19 12.0 0.5 4.3 4 0 0 4 4 4 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Dor1 PF04124.12 EAX89164.1 - 0.011 14.4 0.2 0.57 8.8 0.1 2.2 2 0 0 2 2 2 0 Dor1-like family Mur_ligase_M PF08245.12 EAX89165.1 - 7.4e-08 32.6 0.2 2.6e-07 30.8 0.3 1.7 1 1 0 1 1 1 1 Mur ligase middle domain TAF PF02969.17 EAX89166.1 - 3.3e-06 27.2 2.2 3.9e-06 27.0 0.7 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EAX89166.1 - 0.02 15.3 0.4 0.045 14.1 0.1 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX89166.1 - 0.039 14.0 0.2 0.13 12.3 0.2 1.9 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CREPT PF16566.5 EAX89168.1 - 0.029 14.5 0.2 0.075 13.2 0.2 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX89168.1 - 0.44 10.7 5.0 0.35 11.0 1.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ASL_C PF08328.11 EAX89169.1 - 0.041 14.0 2.3 0.064 13.3 2.3 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal LMBR1 PF04791.16 EAX89169.1 - 0.087 11.7 4.2 0.11 11.4 4.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.12 EAX89170.1 - 0.11 12.3 16.5 0.13 12.1 16.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EAX89170.1 - 0.46 9.9 21.2 0.46 9.9 21.2 1.2 1 0 0 1 1 1 0 SDA1 GerA PF03323.13 EAX89170.1 - 0.6 8.5 1.1 0.77 8.2 1.1 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Presenilin PF01080.17 EAX89170.1 - 1.1 7.9 11.0 1.2 7.8 11.0 1.1 1 0 0 1 1 1 0 Presenilin Pes-10 PF07149.11 EAX89170.1 - 1.4 7.9 16.6 1.7 7.6 16.6 1.3 1 0 0 1 1 1 0 Pes-10 Membralin PF09746.9 EAX89170.1 - 2.1 7.3 4.4 2.2 7.2 4.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein TFIIF_alpha PF05793.12 EAX89170.1 - 2.4 6.6 28.6 3.6 6.1 28.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 EAX89170.1 - 2.8 5.9 9.2 2.8 6.0 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 EAX89170.1 - 5.5 7.0 5.0 6 6.9 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2407_C PF13373.6 EAX89170.1 - 9.5 6.4 7.6 15 5.7 7.6 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain PEP-utilizers_C PF02896.18 EAX89171.1 - 3.1e-18 65.9 0.0 1.1e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 EAX89171.1 - 9.9e-12 44.8 0.0 8e-07 28.6 0.0 3.9 3 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EAX89171.1 - 8.2e-07 28.7 0.0 2.7e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain MID_MedPIWI PF18296.1 EAX89171.1 - 0.17 11.6 3.7 0.33 10.7 3.7 1.4 1 0 0 1 1 1 0 MID domain of medPIWI RP-C_C PF11800.8 EAX89171.1 - 0.35 10.9 4.1 0.81 9.7 4.1 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC53 PF10152.9 EAX89171.1 - 0.41 11.1 12.2 0.93 9.9 12.2 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex rRNA_processing PF08524.11 EAX89171.1 - 0.45 10.5 13.5 1.1 9.3 13.5 1.5 1 0 0 1 1 1 0 rRNA processing Neur_chan_memb PF02932.16 EAX89171.1 - 1.4 8.9 6.5 2.8 8.0 6.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 EAX89171.1 - 3.6 6.5 9.2 7.4 5.5 9.2 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EAX89171.1 - 7.2 5.3 8.5 13 4.4 8.5 1.3 1 0 0 1 1 1 0 Presenilin TMP PF05017.14 EAX89172.1 - 0.053 14.1 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX89174.1 - 2.8e-21 75.3 5.8 2.8e-21 75.3 5.8 3.1 2 1 1 3 3 2 1 Phage tail repeat like DUF3839 PF12943.7 EAX89176.1 - 4.2e-156 517.5 12.3 5.1e-156 517.3 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89176.1 - 0.77 10.3 5.6 8.6 6.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MULE PF10551.9 EAX89177.1 - 2.1e-10 40.8 0.2 5e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX89177.1 - 0.0058 15.5 0.2 0.0095 14.8 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX89177.1 - 0.0061 16.3 0.3 0.034 13.8 0.2 1.9 1 1 1 2 2 2 1 Transposase Vta1 PF04652.16 EAX89177.1 - 0.068 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Vta1 like Parvo_NS1 PF01057.17 EAX89177.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ribosomal_S14 PF00253.21 EAX89178.1 - 1.9e-14 53.2 5.2 2.1e-14 53.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS91 PF14319.6 EAX89178.1 - 0.034 14.2 1.0 0.037 14.1 1.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_2 PF13696.6 EAX89178.1 - 2.2 8.2 7.5 8.4 6.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle ArfGap PF01412.18 EAX89179.1 - 3.6e-25 88.3 4.9 7.2e-25 87.3 4.9 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 EAX89179.1 - 2.8e-12 47.0 0.3 4.3e-11 43.3 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89179.1 - 8e-10 39.1 1.2 0.0005 20.6 0.0 3.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX89179.1 - 4.2e-09 36.5 0.0 0.0021 18.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX89179.1 - 2.5e-07 30.5 0.4 0.012 16.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX89179.1 - 4.3e-05 23.7 0.1 0.0026 18.0 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PH PF00169.29 EAX89179.1 - 0.0016 19.0 0.6 0.0035 17.8 0.2 1.8 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 EAX89180.1 - 4.6e-57 193.2 0.0 7.3e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX89180.1 - 2.2e-53 181.3 0.0 7.4e-53 179.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain OEP PF02321.18 EAX89180.1 - 0.003 17.4 5.3 0.0058 16.5 5.3 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein MscS_porin PF12795.7 EAX89180.1 - 0.0087 15.6 9.3 0.016 14.7 9.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.19 EAX89180.1 - 0.0092 14.0 5.3 0.019 12.9 5.3 1.4 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APH PF01636.23 EAX89180.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FlxA PF14282.6 EAX89180.1 - 0.016 15.1 10.0 0.05 13.6 10.0 1.8 1 0 0 1 1 1 0 FlxA-like protein Syntaxin-6_N PF09177.11 EAX89180.1 - 0.058 14.0 7.7 6.6 7.4 4.6 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.12 EAX89180.1 - 0.06 12.9 3.5 0.11 12.0 3.5 1.3 1 0 0 1 1 1 0 PspA/IM30 family Vps54_N PF10475.9 EAX89180.1 - 0.063 12.5 5.5 0.13 11.5 5.5 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Pkinase_fungal PF17667.1 EAX89180.1 - 0.083 11.7 1.0 0.67 8.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase CLZ PF16526.5 EAX89180.1 - 0.087 13.2 7.6 0.12 12.8 1.1 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC-167 PF15188.6 EAX89180.1 - 0.1 13.0 4.5 0.32 11.3 4.5 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 EAX89180.1 - 0.13 12.8 5.1 0.56 10.7 5.1 2.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 EAX89180.1 - 0.2 10.7 6.8 0.48 9.5 6.8 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EAX89180.1 - 0.27 9.8 9.7 0.1 11.2 4.6 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 EAX89180.1 - 0.52 9.5 2.9 1.4 8.1 2.9 1.6 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 EAX89180.1 - 0.56 10.5 5.8 1.5 9.2 5.8 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4349 PF14257.6 EAX89180.1 - 0.59 9.6 4.6 1.1 8.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1664 PF07889.12 EAX89180.1 - 1.6 8.8 5.1 5.2 7.1 5.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Flagellin_C PF00700.21 EAX89180.1 - 1.8 9.0 8.7 3.3 8.1 2.6 3.3 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Phage_HK97_TLTM PF06120.11 EAX89180.1 - 2.2 7.4 9.1 0.88 8.7 4.4 2.1 2 0 0 2 2 2 0 Tail length tape measure protein Tropomyosin_1 PF12718.7 EAX89180.1 - 2.4 8.3 8.0 8.1 6.6 8.0 1.9 1 1 0 1 1 1 0 Tropomyosin like Fmp27_WPPW PF10359.9 EAX89180.1 - 2.8 6.7 10.8 4.7 5.9 10.5 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain OmpH PF03938.14 EAX89180.1 - 2.9 8.2 8.6 5.3 7.4 4.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4795 PF16043.5 EAX89180.1 - 3.3 7.3 11.1 0.67 9.5 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Cnn_1N PF07989.11 EAX89180.1 - 3.3 7.9 7.3 13 6.1 7.3 2.1 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 EAX89180.1 - 5.8 7.2 13.0 0.48 10.7 7.3 2.1 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.6 EAX89180.1 - 7 7.1 9.0 30 5.1 9.0 2.1 1 1 0 1 1 1 0 Snapin/Pallidin YscO-like PF16789.5 EAX89180.1 - 7 6.7 7.3 3.8 7.5 0.4 2.3 2 0 0 2 2 2 0 YscO-like protein SlyX PF04102.12 EAX89180.1 - 8.3 7.1 6.6 31 5.3 1.1 2.7 1 1 1 2 2 2 0 SlyX Gly_rich PF12810.7 EAX89181.1 - 3.3e-49 168.0 39.8 3.9e-49 167.8 39.8 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX89182.1 - 5.5e-30 105.1 40.6 6.5e-30 104.8 40.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX89183.1 - 1.6e-26 93.7 38.6 1.9e-26 93.5 38.6 1.0 1 0 0 1 1 1 1 Glycine rich protein F5_F8_type_C PF00754.25 EAX89184.1 - 5.4e-06 26.6 0.0 8.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain SUKH_5 PF14567.6 EAX89184.1 - 0.71 9.6 6.0 0.57 9.9 4.7 1.5 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall BNR_2 PF13088.6 EAX89185.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain DUF4107 PF13389.6 EAX89188.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX89189.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase SecE PF00584.20 EAX89190.1 - 5e-08 32.8 0.3 5.8e-08 32.5 0.3 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ank_2 PF12796.7 EAX89191.1 - 1e-59 199.1 0.9 2.7e-14 53.5 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89191.1 - 1e-42 143.9 0.0 4.1e-10 40.0 0.0 6.8 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89191.1 - 1.4e-36 124.0 0.0 6.8e-07 29.4 0.0 7.6 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX89191.1 - 1.5e-36 123.2 0.1 0.00017 21.9 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX89191.1 - 8e-34 111.9 0.1 0.0017 18.6 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat Pribosyltran_N PF13793.6 EAX89191.1 - 0.16 11.9 0.3 1.3 9.0 0.0 2.5 4 0 0 4 4 4 0 N-terminal domain of ribose phosphate pyrophosphokinase Gly_rich PF12810.7 EAX89192.1 - 1.9e-21 77.1 12.0 2.3e-21 76.8 12.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Chon_Sulph_att PF06566.11 EAX89192.1 - 0.022 14.6 1.4 0.037 13.9 1.4 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Ank_2 PF12796.7 EAX89193.1 - 2.4e-29 101.8 0.2 1.7e-16 60.6 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89193.1 - 1.6e-20 73.2 0.1 1.9e-06 28.3 0.0 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89193.1 - 2.3e-19 68.9 1.5 9.7e-05 22.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX89193.1 - 7.6e-19 65.8 0.1 0.0015 18.9 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX89193.1 - 4.5e-13 49.1 0.0 2.7e-05 24.3 0.0 4.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) DUF4942 PF13708.6 EAX89193.1 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) Ank_2 PF12796.7 EAX89194.1 - 7.6e-22 77.7 0.0 4e-14 52.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89194.1 - 4.7e-20 71.1 0.4 4.2e-06 27.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX89194.1 - 2.7e-16 59.7 0.1 1.7e-10 41.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89194.1 - 6.7e-16 56.8 0.1 3.7e-05 23.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX89194.1 - 1.1e-11 44.8 0.1 7.8e-05 22.9 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89195.1 - 1.2e-61 205.3 1.0 1.7e-21 76.6 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89195.1 - 2.9e-36 123.4 0.0 8.9e-11 42.1 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX89195.1 - 3.9e-29 99.8 0.0 4.7e-05 23.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX89195.1 - 6.5e-28 93.7 0.0 0.00048 20.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX89195.1 - 3.5e-27 94.1 0.0 1.7e-07 31.4 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX89195.1 - 0.058 13.1 1.1 1.9 8.1 0.1 2.3 2 1 0 2 2 2 0 Shigella flexneri OspC protein YppF PF14178.6 EAX89195.1 - 0.083 12.8 0.0 7.4 6.5 0.0 3.2 3 0 0 3 3 3 0 YppF-like protein Ank_2 PF12796.7 EAX89196.1 - 1.3e-08 35.3 0.1 7.5e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89196.1 - 2.8e-07 31.0 0.0 0.0014 19.1 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89196.1 - 5.6e-07 29.7 0.0 8e-05 22.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89196.1 - 0.014 15.9 0.0 5.5 7.9 0.0 4.2 3 0 0 3 3 3 0 Ankyrin repeat DUF4363 PF14276.6 EAX89196.1 - 0.07 13.2 7.5 2.4 8.3 4.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Ank PF00023.30 EAX89196.1 - 0.071 13.6 0.1 15 6.3 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat Gly_rich PF12810.7 EAX89197.1 - 1.3e-48 166.0 24.3 1.7e-48 165.7 24.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Chon_Sulph_att PF06566.11 EAX89197.1 - 0.054 13.3 1.4 0.11 12.4 1.4 1.4 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Ank_2 PF12796.7 EAX89198.1 - 2.4e-51 172.2 7.2 2.8e-18 66.3 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89198.1 - 2.3e-39 133.3 5.7 1.4e-10 41.4 0.0 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX89198.1 - 9.2e-36 120.7 4.5 8.9e-07 29.1 0.3 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX89198.1 - 6.1e-32 106.1 3.5 0.00031 21.0 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX89198.1 - 1.6e-29 101.6 9.8 8.4e-08 32.3 0.2 6.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) FmdA_AmdA PF03069.15 EAX89198.1 - 0.0012 17.8 0.1 0.0087 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetamidase/Formamidase family Dioxygenase_N PF04444.14 EAX89198.1 - 0.12 12.2 0.0 63 3.5 0.0 4.0 4 1 1 5 5 5 0 Catechol dioxygenase N terminus SASRP1 PF15160.6 EAX89199.1 - 0.077 12.7 0.7 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 Tn7_Tnp_TnsA_C PF08721.11 EAX89199.1 - 0.14 12.8 2.6 0.23 12.1 0.1 2.5 3 1 0 3 3 3 0 TnsA endonuclease C terminal Ank_2 PF12796.7 EAX89200.1 - 7.7e-130 423.8 12.3 2.3e-17 63.4 0.1 10.4 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89200.1 - 6.4e-99 320.5 1.7 2.1e-05 24.8 0.0 18.8 19 0 0 19 19 19 18 Ankyrin repeat Ank_4 PF13637.6 EAX89200.1 - 8.6e-93 303.6 0.3 8.5e-10 39.0 0.0 13.6 8 4 5 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89200.1 - 8.5e-81 265.0 1.1 7.9e-07 29.2 0.0 17.6 3 3 15 18 18 18 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89200.1 - 1.6e-76 243.0 2.6 0.0026 18.1 0.0 19.0 19 0 0 19 19 19 15 Ankyrin repeat YfmQ PF10787.9 EAX89200.1 - 7.4e-06 25.8 2.5 2.2 8.1 0.0 6.7 2 1 2 7 7 7 1 Uncharacterised protein from bacillus cereus group mTERF PF02536.14 EAX89200.1 - 0.00045 19.3 2.3 5.4 5.8 0.1 5.1 3 2 1 5 5 5 2 mTERF DUF3083 PF11281.8 EAX89200.1 - 0.0024 17.2 0.9 15 4.8 0.0 5.1 2 2 2 6 6 6 0 Protein of unknown function (DUF3083) DUF5049 PF16468.5 EAX89200.1 - 0.0044 16.9 4.5 16 5.5 0.0 7.2 11 0 0 11 11 10 0 Domain of unknown function (DUF5049) DUF4105 PF13387.6 EAX89200.1 - 0.0045 16.7 0.0 0.1 12.2 0.0 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4105) FmdA_AmdA PF03069.15 EAX89200.1 - 0.0061 15.5 2.3 35 3.1 0.0 5.2 2 2 4 6 6 6 0 Acetamidase/Formamidase family GUN4_N PF16416.5 EAX89200.1 - 0.022 14.7 0.0 51 4.0 0.0 5.6 7 1 1 8 8 8 0 ARM-like repeat domain, GUN4-N terminal Peptidase_S24 PF00717.23 EAX89200.1 - 0.057 13.4 0.7 6.8 6.7 0.0 4.2 4 1 1 5 5 5 0 Peptidase S24-like EPSP_synthase PF00275.20 EAX89200.1 - 0.11 11.1 3.9 4.3 5.9 0.0 4.1 5 1 1 6 6 6 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ribosomal_L30 PF00327.20 EAX89200.1 - 1.9 8.4 8.8 76 3.3 0.0 6.4 8 0 0 8 8 8 0 Ribosomal protein L30p/L7e Phage_T7_Capsid PF05396.11 EAX89200.1 - 4.9 7.5 9.9 40 4.6 0.1 5.9 5 3 1 7 7 7 0 Phage T7 capsid assembly protein TFIID_30kDa PF03540.13 EAX89202.1 - 8.2e-17 60.9 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIID-31kDa PF02291.15 EAX89202.1 - 0.00085 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF4 PF05236.14 EAX89202.1 - 0.00093 19.0 0.2 0.0013 18.6 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family EF-hand_14 PF17959.1 EAX89202.1 - 0.0012 19.1 0.1 0.18 12.1 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain TFIID_20kDa PF03847.13 EAX89202.1 - 0.088 13.3 1.8 0.24 11.9 1.8 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A ERp29 PF07749.12 EAX89203.1 - 6.2e-17 62.3 0.2 1.7e-16 60.9 0.2 1.7 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin PF00085.20 EAX89203.1 - 5.5e-11 42.4 0.0 7.1e-05 22.8 0.0 2.5 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EAX89203.1 - 7.5e-07 29.2 0.0 0.26 11.2 0.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Imm12 PF15560.6 EAX89203.1 - 0.12 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 12 Thioredoxin_2 PF13098.6 EAX89203.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Ribosomal_L22e PF01776.17 EAX89204.1 - 7e-27 94.0 1.1 7.6e-27 93.9 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1912 PF08930.10 EAX89204.1 - 0.021 14.9 0.3 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Ras PF00071.22 EAX89205.1 - 8.2e-46 155.6 0.1 9.5e-46 155.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89205.1 - 2.5e-16 60.0 0.0 4.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89205.1 - 7.4e-07 28.8 0.0 9.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX89205.1 - 0.00031 20.3 0.0 0.00058 19.5 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX89205.1 - 0.0017 18.3 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EAX89205.1 - 0.011 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 EAX89205.1 - 0.024 14.2 0.0 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ARL2_Bind_BART PF11527.8 EAX89205.1 - 0.24 11.5 0.2 0.24 11.5 0.2 2.3 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART PEP-utilizers_C PF02896.18 EAX89206.1 - 1.9e-15 56.7 0.0 5.8e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EAX89206.1 - 6.2e-10 38.7 2.9 7.7e-10 38.3 0.2 2.4 3 0 0 3 3 3 1 PEP-utilising enzyme, mobile domain DUF5105 PF17118.5 EAX89206.1 - 0.031 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) DUF4476 PF14771.6 EAX89206.1 - 0.11 12.8 0.5 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) TMP PF05017.14 EAX89208.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat BRO1 PF03097.18 EAX89210.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX89210.1 - 5.6 7.4 8.1 18 5.9 1.8 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat Not1 PF04054.15 EAX89213.1 - 2.2e-51 174.9 5.0 2.2e-51 174.9 5.0 4.8 4 1 1 5 5 5 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAX89213.1 - 2e-18 66.6 2.2 2e-18 66.6 2.2 3.6 3 1 1 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EAX89213.1 - 7.7e-07 28.5 8.5 7.7e-07 28.5 8.5 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain ZNRF_3_ecto PF18212.1 EAX89213.1 - 0.039 14.0 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 ZNRF-3 Ectodomain FAS_meander PF17951.1 EAX89213.1 - 1.5 8.7 9.0 1.8 8.4 0.0 3.6 4 0 0 4 4 4 0 Fatty acid synthase meander beta sheet domain P3A PF08727.11 EAX89214.1 - 0.068 12.6 0.3 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Poliovirus 3A protein like Radial_spoke_3 PF06098.11 EAX89215.1 - 6.1e-43 147.1 8.6 6.1e-43 147.1 8.6 2.1 1 1 1 2 2 2 1 Radial spoke protein 3 zf-C3HC4_3 PF13920.6 EAX89219.1 - 0.0025 17.6 4.8 0.0066 16.3 4.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TpcC PF12642.7 EAX89219.1 - 0.0064 16.3 1.2 0.0091 15.8 1.2 1.1 1 0 0 1 1 1 1 Conjugative transposon protein TcpC DZR PF12773.7 EAX89219.1 - 0.0069 16.4 0.8 0.021 14.8 0.8 1.8 1 0 0 1 1 1 1 Double zinc ribbon Prok-RING_4 PF14447.6 EAX89219.1 - 0.067 13.1 6.3 0.23 11.4 6.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 MH1 PF03165.16 EAX89219.1 - 0.087 13.0 0.6 0.41 10.9 0.6 2.0 1 1 0 1 1 1 0 MH1 domain Laps PF10169.9 EAX89219.1 - 0.19 12.3 1.0 0.29 11.7 1.0 1.4 1 1 0 1 1 1 0 Learning-associated protein Telomere_reg-2 PF10193.9 EAX89219.1 - 0.39 11.2 2.5 0.64 10.5 2.5 1.4 1 1 0 1 1 1 0 Telomere length regulation protein TerY_C PF15616.6 EAX89219.1 - 0.56 10.3 4.8 1.1 9.4 4.8 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain NIF PF03031.18 EAX89220.1 - 4.7e-52 175.9 0.1 6.9e-52 175.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Myb_DNA-binding PF00249.31 EAX89221.1 - 4.7e-43 145.1 12.2 5.3e-16 58.5 0.1 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89221.1 - 3.7e-38 129.6 10.4 2e-16 60.0 0.2 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89221.1 - 1.9e-06 27.7 1.6 0.0023 17.8 0.0 3.2 3 0 0 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 EAX89221.1 - 4.1e-05 23.6 4.5 0.53 10.4 0.1 3.2 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EAX89221.1 - 0.00084 19.3 0.2 1.9 8.5 0.0 3.2 2 1 0 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 EAX89221.1 - 0.001 19.2 1.3 1.1 9.5 0.0 3.2 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAX89221.1 - 0.0071 16.5 2.1 1 9.6 0.0 3.4 1 1 2 3 3 3 1 Rap1 Myb domain DUF2448 PF10476.9 EAX89221.1 - 0.21 11.4 0.1 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) G6PD_C PF02781.16 EAX89222.1 - 2.3e-94 315.8 0.0 4.9e-94 314.8 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 EAX89222.1 - 1.8e-57 194.8 0.0 2.8e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 EAX89222.1 - 1.1e-52 179.2 0.1 2e-52 178.4 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Aa_trans PF01490.18 EAX89223.1 - 6.2e-21 74.6 34.4 7.8e-21 74.3 34.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ETRAMP PF09716.10 EAX89223.1 - 0.3 11.2 10.9 0.81 9.8 0.2 4.4 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 EAX89225.1 - 1.1e-71 241.3 0.0 1.5e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89225.1 - 7.1e-37 127.1 0.0 9.5e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX89225.1 - 1.9e-08 34.8 1.2 4.7e-08 33.5 1.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX89225.1 - 8.6e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX89225.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 EAX89225.1 - 0.095 13.0 0.1 0.095 13.0 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain DDR PF08841.10 EAX89228.1 - 0.16 10.9 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX89229.1 - 0.0053 16.7 6.7 0.0082 16.1 6.7 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX89230.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX89230.1 - 0.09 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX89231.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX89231.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX89232.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX89233.1 - 2.5e-09 36.5 2.2 1.4e-08 34.0 2.2 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DENN PF02141.21 EAX89234.1 - 2.7e-20 73.1 1.2 1e-19 71.2 1.2 2.1 1 0 0 1 1 1 1 DENN (AEX-3) domain Ycf9 PF01737.17 EAX89234.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 YCF9 Adeno_E3_CR2 PF02439.15 EAX89236.1 - 0.00046 19.9 3.6 0.00071 19.3 3.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EAX89236.1 - 0.0011 19.8 0.1 0.0021 18.9 0.1 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 EAX89236.1 - 0.0066 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.6 EAX89236.1 - 0.0076 16.5 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EAX89236.1 - 0.0088 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF5385 PF17359.2 EAX89236.1 - 0.012 15.2 2.8 0.015 14.8 2.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5385) Orthoreo_P10 PF07204.11 EAX89236.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Protocadherin PF08374.11 EAX89236.1 - 0.015 15.2 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Phage_Gp23 PF10669.9 EAX89236.1 - 0.03 14.7 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SARAF PF06682.12 EAX89236.1 - 0.031 13.9 0.3 0.037 13.7 0.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MAP17 PF15807.5 EAX89236.1 - 0.034 14.4 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2615 PF11027.8 EAX89236.1 - 0.038 14.1 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) BatA PF07584.11 EAX89236.1 - 0.048 14.0 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal ASFV_J13L PF05568.11 EAX89236.1 - 0.064 13.0 2.9 0.056 13.2 1.6 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein Cadherin_C_2 PF16492.5 EAX89236.1 - 0.078 13.7 0.1 0.22 12.3 0.1 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Polysacc_synt PF01943.17 EAX89236.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SID-1_RNA_chan PF13965.6 EAX89236.1 - 0.13 10.7 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 EAX89236.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PspB PF06667.12 EAX89236.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B Syndecan PF01034.20 EAX89236.1 - 3.2 7.7 5.2 2.7 7.9 2.7 2.2 1 1 1 2 2 2 0 Syndecan domain Myb_DNA-binding PF00249.31 EAX89237.1 - 9.5e-20 70.5 7.3 1.5e-09 37.8 1.8 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89237.1 - 1.1e-15 57.6 7.5 4.9e-12 45.9 2.8 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89237.1 - 4.4e-05 23.5 0.8 0.32 11.0 0.1 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX89237.1 - 0.0048 16.8 3.3 0.01 15.7 0.2 2.2 1 1 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAX89237.1 - 0.0082 16.4 3.9 0.023 15.0 1.8 2.2 1 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 EAX89237.1 - 0.012 15.7 2.7 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PriCT_2 PF08707.11 EAX89237.1 - 0.066 13.6 1.6 0.13 12.6 1.6 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) SnAPC_2_like PF11035.8 EAX89237.1 - 0.13 12.4 0.4 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Ank_2 PF12796.7 EAX89239.1 - 1.3e-43 147.5 22.8 1e-18 67.7 3.0 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89239.1 - 8.8e-43 142.9 3.9 3.7e-08 33.5 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX89239.1 - 1.4e-39 133.6 22.3 1.5e-12 47.4 0.8 7.8 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89239.1 - 1.5e-38 130.6 16.8 2.5e-11 43.8 0.1 9.3 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89239.1 - 2e-34 113.7 19.3 9.1e-07 28.7 0.0 9.3 9 2 1 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX89239.1 - 2.1e-31 107.7 7.4 2.1e-31 107.7 7.4 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) BRCT PF00533.26 EAX89239.1 - 0.06 13.7 0.2 23 5.5 0.0 3.9 2 2 2 4 4 4 0 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.13 EAX89242.1 - 4.5e-34 116.7 0.4 1.1e-33 115.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX89242.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX89242.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FPN1 PF06963.12 EAX89242.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pox_A32 PF04665.12 EAX89243.1 - 8.5e-07 28.7 2.5 8.5e-07 28.7 2.5 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX89243.1 - 3.3e-05 23.7 0.3 0.32 10.7 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX89243.1 - 4.6e-05 23.7 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX89243.1 - 0.00028 20.9 4.1 0.00058 19.9 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89243.1 - 0.00076 19.3 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89243.1 - 0.0024 17.7 1.2 0.0043 16.9 0.7 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89243.1 - 0.0065 16.1 2.9 0.016 14.9 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89243.1 - 0.015 15.7 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 EAX89243.1 - 0.084 12.9 0.7 1.2 9.1 0.7 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain AAA_25 PF13481.6 EAX89243.1 - 0.091 12.3 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89243.1 - 0.11 12.9 0.1 0.95 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89243.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89243.1 - 0.61 10.4 4.4 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX89243.1 - 0.72 10.6 11.7 0.34 11.6 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 LRR_5 PF13306.6 EAX89244.1 - 2e-77 257.3 5.3 2.2e-33 114.9 0.0 4.1 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89244.1 - 7.1e-05 22.5 0.0 17 5.3 0.0 5.7 6 1 1 7 7 7 0 Leucine rich repeat VSP PF03302.13 EAX89244.1 - 0.00068 18.6 0.7 0.0012 17.8 0.7 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EAX89244.1 - 0.0009 19.4 1.1 0.0032 17.6 1.1 1.9 1 0 0 1 1 1 1 Podoplanin ECSCR PF15820.5 EAX89244.1 - 0.011 15.6 0.4 0.031 14.1 0.4 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CYYR1 PF10873.8 EAX89244.1 - 0.011 16.2 1.4 0.021 15.3 1.4 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 SKG6 PF08693.10 EAX89244.1 - 0.033 13.6 7.2 0.061 12.7 7.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EAX89244.1 - 0.034 14.1 1.0 0.074 13.0 1.0 1.6 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EAX89244.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 EAX89244.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF5385 PF17359.2 EAX89244.1 - 0.074 12.6 0.8 0.1 12.1 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) PAF-AH_p_II PF03403.13 EAX89244.1 - 0.091 11.3 0.1 0.42 9.1 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Glycophorin_A PF01102.18 EAX89244.1 - 0.092 13.0 0.3 0.21 11.8 0.0 1.7 2 0 0 2 2 1 0 Glycophorin A EphA2_TM PF14575.6 EAX89244.1 - 0.1 13.5 1.1 0.21 12.5 1.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 EAX89244.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 EAX89244.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless YajC PF02699.15 EAX89244.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.4 3 0 0 3 3 3 0 Preprotein translocase subunit FeoB_associated PF12669.7 EAX89244.1 - 0.19 12.2 3.6 0.39 11.1 3.6 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein BetaGal_dom3 PF13363.6 EAX89244.1 - 0.77 9.4 3.4 18 5.0 0.1 4.1 4 1 1 5 5 5 0 Beta-galactosidase, domain 3 Borrelia_P13 PF05628.12 EAX89244.1 - 3 7.8 17.1 4.5 7.2 0.1 5.2 4 1 3 7 7 7 0 Borrelia membrane protein P13 FNIP PF05725.12 EAX89244.1 - 4.6 7.5 8.5 7.2 6.9 0.0 5.3 9 0 0 9 9 8 0 FNIP Repeat B56 PF01603.20 EAX89245.1 - 2.8e-97 326.3 16.9 4e-97 325.8 16.9 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PSP PF04046.16 EAX89246.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89247.1 - 0.061 13.9 5.4 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX89249.1 - 4.1e-16 58.8 5.1 4.1e-16 58.8 5.1 4.8 4 1 0 4 4 4 1 Phage tail repeat like YmaF PF12788.7 EAX89249.1 - 0.032 14.7 11.3 2 9.0 3.3 3.4 2 1 0 2 2 2 0 YmaF family DUF4116 PF13475.6 EAX89249.1 - 0.034 13.9 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Gp5_C PF06715.12 EAX89249.1 - 1.6 9.1 4.6 1.6 9.0 0.3 3.4 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) DUF3839 PF12943.7 EAX89252.1 - 1.1e-156 519.5 11.5 1.4e-156 519.2 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX89252.1 - 0.068 13.6 1.6 0.16 12.4 0.3 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX89252.1 - 0.3 11.6 4.0 5.4 7.5 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX89252.1 - 1.4 9.4 5.4 0.45 11.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 EAX89252.1 - 3.6 8.0 7.3 12 6.3 0.1 3.8 3 2 1 4 4 4 0 Tup N-terminal YlqD PF11068.8 EAX89253.1 - 0.019 15.3 5.5 0.023 15.1 5.5 1.0 1 0 0 1 1 1 0 YlqD protein Seryl_tRNA_N PF02403.22 EAX89253.1 - 0.031 14.5 3.6 0.038 14.2 1.4 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1773 PF08593.10 EAX89253.1 - 0.032 15.3 0.2 0.051 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function Tropomyosin_1 PF12718.7 EAX89253.1 - 0.062 13.4 9.1 0.12 12.5 9.1 1.5 1 1 0 1 1 1 0 Tropomyosin like E2F_CC-MB PF16421.5 EAX89253.1 - 0.08 13.3 4.7 0.15 12.4 4.7 1.6 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain DUF2205 PF10224.9 EAX89253.1 - 0.11 12.5 3.1 0.19 11.7 3.1 1.4 1 0 0 1 1 1 0 Short coiled-coil protein DUF3450 PF11932.8 EAX89253.1 - 0.16 11.2 4.6 0.2 10.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Allexi_40kDa PF05549.11 EAX89253.1 - 0.18 11.3 1.8 0.22 11.0 0.8 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein CdvA PF18822.1 EAX89253.1 - 0.2 11.5 6.1 2.6 7.9 2.0 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain NYD-SP28_assoc PF14775.6 EAX89253.1 - 0.24 11.5 5.3 0.43 10.7 2.3 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain DDE_1 PF03184.19 EAX89255.1 - 4.4e-07 29.7 0.0 5.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX89255.1 - 3.1e-05 23.8 0.0 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.9 EAX89257.1 - 2.5e-11 43.8 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX89257.1 - 0.012 16.0 0.7 0.27 11.7 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAX89257.1 - 0.013 15.6 3.0 0.026 14.6 3.0 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF4065 PF13274.6 EAX89257.1 - 0.14 13.1 0.7 1.7 9.5 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF4065) DUF4106 PF13388.6 EAX89260.1 - 7.7e-274 908.2 19.8 1.2e-273 907.6 19.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX89260.1 - 0.041 14.2 0.1 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated DUF4108 PF13390.6 EAX89261.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX89262.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX89263.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89263.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89263.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89263.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89263.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89263.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89263.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89263.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89263.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89263.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89263.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89263.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1493 PF07377.12 EAX89264.1 - 0.069 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pkinase PF00069.25 EAX89265.1 - 8.4e-41 140.1 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89265.1 - 1.6e-21 76.8 0.0 2e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89265.1 - 1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX89265.1 - 0.00063 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 EAX89265.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.11 EAX89265.1 - 0.014 14.4 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EAX89265.1 - 0.047 13.3 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EAX89265.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family EGF_3 PF12947.7 EAX89266.1 - 0.44 10.8 21.8 0.11 12.7 10.4 3.4 3 1 0 3 3 3 0 EGF domain hEGF PF12661.7 EAX89266.1 - 0.45 11.2 13.6 2.5 8.8 0.1 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 EAX89266.1 - 7.3 7.0 14.7 5.9 7.3 0.3 3.4 3 0 0 3 3 3 0 Pvs28 EGF domain TMEMspv1-c74-12 PF11044.8 EAX89266.1 - 8.5 6.5 8.5 0.18 11.8 0.7 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4106 PF13388.6 EAX89267.1 - 4.3e-121 405.1 19.2 5e-121 404.8 19.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Orn_Arg_deC_N PF02784.16 EAX89268.1 - 3.2e-65 219.9 0.0 4.2e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EAX89268.1 - 7.1e-12 45.4 0.0 1.1e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LRR_4 PF12799.7 EAX89269.1 - 0.00054 20.3 0.8 0.0018 18.6 0.1 2.3 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) PDZ_6 PF17820.1 EAX89269.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Gly_rich PF12810.7 EAX89270.1 - 2.9e-46 158.4 23.0 3.6e-46 158.1 23.0 1.1 1 0 0 1 1 1 1 Glycine rich protein Flavodoxin_2 PF02525.17 EAX89271.1 - 5.4e-36 124.2 0.0 6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX89271.1 - 9.3e-06 25.5 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase GerD PF17898.1 EAX89272.1 - 0.014 15.3 2.3 0.03 14.3 0.4 2.6 2 0 0 2 2 2 0 Spore germination GerD central core domain Ank_2 PF12796.7 EAX89275.1 - 2.2e-17 63.4 0.3 1.6e-13 51.0 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89275.1 - 3.1e-14 53.1 0.5 2.2e-07 31.3 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89275.1 - 3.5e-12 46.3 0.6 5.5e-07 29.7 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89275.1 - 2.2e-09 36.8 0.1 0.16 12.6 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX89275.1 - 2e-06 28.0 0.0 1.9 9.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat SSrecog PF03531.14 EAX89277.1 - 7.3e-05 22.6 2.0 1.6 8.7 0.1 4.4 1 1 3 4 4 4 2 Structure-specific recognition protein (SSRP1) DUF1899 PF08953.11 EAX89278.1 - 7.7e-21 73.7 0.1 5.2e-20 71.1 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EAX89278.1 - 3.9e-10 39.5 0.0 6.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EAX89278.1 - 3e-09 37.3 0.1 0.00017 22.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX89278.1 - 3.5e-05 24.0 0.7 0.3 11.4 0.1 2.9 2 1 1 3 3 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX89278.1 - 0.0003 19.9 0.0 0.0032 16.5 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_1 PF00170.21 EAX89278.1 - 0.016 15.3 2.9 0.028 14.5 2.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EAX89278.1 - 0.017 15.2 5.2 0.044 13.9 5.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Mt_ATP-synt_D PF05873.12 EAX89278.1 - 0.033 14.1 0.5 0.071 13.0 0.5 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DivIC PF04977.15 EAX89278.1 - 0.066 13.0 5.3 0.24 11.2 5.3 2.0 1 0 0 1 1 1 0 Septum formation initiator WD40_alt PF14077.6 EAX89278.1 - 0.11 12.4 2.2 0.2 11.5 2.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif HALZ PF02183.18 EAX89278.1 - 0.11 12.7 2.5 0.26 11.5 2.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prefoldin PF02996.17 EAX89278.1 - 0.12 12.3 1.1 0.27 11.2 1.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit TSC22 PF01166.18 EAX89278.1 - 0.24 11.8 4.8 0.5 10.7 4.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family IFP_35_N PF07334.13 EAX89278.1 - 0.28 11.3 3.3 0.76 9.9 3.3 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ZapB PF06005.12 EAX89278.1 - 0.31 11.5 5.9 0.73 10.3 5.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 EAX89278.1 - 0.84 10.2 5.9 1.7 9.2 5.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EAX89278.1 - 1.3 9.5 3.7 2.5 8.6 1.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A32 PF04665.12 EAX89282.1 - 7.8e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX89282.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX89282.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX89282.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MULE PF10551.9 EAX89283.1 - 5.3e-11 42.8 0.3 1.3e-10 41.5 0.3 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX89283.1 - 0.0066 15.3 0.2 0.013 14.4 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX89283.1 - 0.008 15.9 0.4 0.051 13.3 0.1 1.9 1 1 1 2 2 2 1 Transposase FAR1 PF03101.15 EAX89283.1 - 0.071 13.8 0.1 0.16 12.7 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Vta1 PF04652.16 EAX89283.1 - 0.094 12.7 1.2 0.14 12.1 0.3 1.7 2 0 0 2 2 2 0 Vta1 like DUF3839 PF12943.7 EAX89284.1 - 5.9e-156 517.1 14.2 7.5e-156 516.7 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89284.1 - 0.46 11.0 6.2 0.93 10.0 1.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX89284.1 - 1 9.7 3.6 4.6 7.6 0.0 3.2 2 2 0 2 2 2 0 Rx N-terminal domain ComA PF02679.15 EAX89285.1 - 0.085 12.3 1.1 0.1 12.0 1.1 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Pox_A32 PF04665.12 EAX89287.1 - 4.2e-07 29.7 0.2 9e-07 28.6 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein Amidase02_C PF12123.8 EAX89288.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX89289.1 - 5.9e-66 221.6 14.8 8.7e-64 214.6 14.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX89289.1 - 0.098 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta UCH PF00443.29 EAX89290.1 - 2.5e-39 135.3 2.3 2.5e-39 135.3 2.3 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX89290.1 - 2.9e-05 23.8 4.1 0.0092 15.6 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 EAX89291.1 - 7.4e-70 235.3 0.0 9.6e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89291.1 - 6.5e-40 137.0 0.0 9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89291.1 - 1.2e-06 28.1 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX89291.1 - 3.9e-06 26.1 1.0 6.3e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EAX89291.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EAX89291.1 - 0.0035 16.2 0.0 0.0051 15.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAX89291.1 - 0.056 13.0 1.0 0.11 12.1 1.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAX89291.1 - 0.072 12.4 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX89291.1 - 0.074 13.0 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF641 PF04859.12 EAX89292.1 - 0.04 14.2 2.1 0.062 13.6 2.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX89292.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor AAA_18 PF13238.6 EAX89293.1 - 7e-05 23.4 0.1 0.00038 21.0 0.1 2.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EAX89293.1 - 0.03 14.0 1.4 0.16 11.6 0.1 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Joubert PF15392.6 EAX89293.1 - 0.039 13.7 0.4 0.077 12.7 0.4 1.4 1 0 0 1 1 1 0 Joubert syndrome-associated Zeta_toxin PF06414.12 EAX89293.1 - 0.046 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin EF-hand_8 PF13833.6 EAX89293.1 - 0.061 13.2 0.0 2.3 8.1 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain pair AAA_28 PF13521.6 EAX89293.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 EAX89293.1 - 0.08 12.5 0.7 3.9 7.2 0.1 3.1 2 0 0 2 2 2 0 EF hand APS_kinase PF01583.20 EAX89293.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Herpes_BLRF2 PF05812.12 EAX89293.1 - 2 8.6 4.7 22 5.2 0.0 3.9 4 0 0 4 4 4 0 Herpesvirus BLRF2 protein ABC2_membrane_3 PF12698.7 EAX89293.1 - 4.8 6.2 6.1 2.1 7.3 1.6 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Alpha-amylase PF00128.24 EAX89294.1 - 2.9e-43 148.7 0.2 1.3e-25 90.7 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Kazal_1 PF00050.21 EAX89294.1 - 0.025 14.6 0.7 0.058 13.4 0.7 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Malt_amylase_C PF16657.5 EAX89294.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Peptidase_S8 PF00082.22 EAX89295.1 - 4.5e-34 118.1 2.8 7.7e-34 117.3 2.8 1.3 1 0 0 1 1 1 1 Subtilase family DUF3328 PF11807.8 EAX89295.1 - 0.007 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PTPRCAP PF15713.5 EAX89295.1 - 0.068 13.5 2.8 0.13 12.5 2.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4834 PF16118.5 EAX89295.1 - 0.12 13.3 0.0 0.34 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Myb_DNA-binding PF00249.31 EAX89296.1 - 1.8e-23 82.5 0.6 7.6e-13 48.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89296.1 - 7.5e-23 80.6 1.1 3.4e-16 59.2 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89296.1 - 5.3e-05 23.2 0.0 0.026 14.6 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX89296.1 - 0.00096 19.0 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX89296.1 - 0.039 14.1 0.3 6.2 7.1 0.0 2.7 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 EAX89296.1 - 5.1 7.3 8.7 33 4.7 0.8 3.7 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Tho2 PF11262.8 EAX89297.1 - 0.055 12.7 3.1 0.059 12.6 3.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KilA-N PF04383.13 EAX89298.1 - 1.6e-43 147.1 0.9 2.3e-43 146.6 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX89298.1 - 0.021 15.4 0.0 0.051 14.2 0.0 1.6 2 0 0 2 2 2 0 Parathyroid hormone family Phage_fiber PF03335.13 EAX89300.1 - 0.83 10.0 7.0 2.7 8.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat TMP PF05017.14 EAX89301.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89302.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX89303.1 - 5.7e-19 68.5 2.3 7.1e-10 39.3 0.0 3.4 2 1 2 4 4 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89303.1 - 1.5e-14 52.6 0.0 0.0016 18.8 0.0 5.4 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX89303.1 - 6.1e-11 42.3 0.6 0.011 16.0 0.0 4.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89303.1 - 8.7e-11 42.1 0.0 0.0043 17.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX89303.1 - 1.9e-07 31.2 0.0 0.0024 18.2 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeat DUF4200 PF13863.6 EAX89303.1 - 2.2e-05 24.9 35.6 0.00044 20.6 22.9 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF3552 PF12072.8 EAX89303.1 - 0.00049 19.6 24.9 0.00049 19.6 24.9 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) AAA_13 PF13166.6 EAX89303.1 - 0.00082 18.2 21.7 0.0011 17.8 21.7 1.2 1 0 0 1 1 1 1 AAA domain KASH_CCD PF14662.6 EAX89303.1 - 0.0035 17.2 27.9 0.0035 17.2 27.9 1.6 2 0 0 2 2 1 1 Coiled-coil region of CCDC155 or KASH Bacillus_HBL PF05791.11 EAX89303.1 - 0.0094 15.8 3.9 0.0094 15.8 3.9 2.6 2 1 1 3 3 2 1 Bacillus haemolytic enterotoxin (HBL) DUF812 PF05667.11 EAX89303.1 - 0.044 12.7 31.1 0.26 10.1 32.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.11 EAX89303.1 - 0.079 13.2 31.7 0.12 12.6 10.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Phage_tail_NK PF16532.5 EAX89303.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales DUF4201 PF13870.6 EAX89303.1 - 0.13 11.9 32.1 0.31 10.7 32.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) HMMR_N PF15905.5 EAX89303.1 - 0.15 11.5 38.5 0.57 9.6 38.3 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 EAX89303.1 - 0.25 11.8 31.3 0.57 10.6 18.9 2.2 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 EAX89303.1 - 0.3 9.9 38.5 0.34 9.8 9.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EAX89303.1 - 0.98 7.3 18.5 1.3 6.8 18.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CC2-LZ PF16516.5 EAX89303.1 - 1.1 9.6 34.6 0.37 11.2 6.9 3.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Presenilin PF01080.17 EAX89303.1 - 2.3 6.9 8.2 2.7 6.7 8.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EAX89303.1 - 2.4 7.4 27.2 62 2.8 27.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EAX89303.1 - 2.4 8.5 31.7 1.3 9.4 3.7 3.9 2 1 0 3 3 3 0 Csm1 N-terminal domain FAM76 PF16046.5 EAX89303.1 - 2.4 7.4 33.7 1.9 7.8 12.4 2.4 1 1 1 2 2 2 0 FAM76 protein FliJ PF02050.16 EAX89303.1 - 2.7 8.2 33.5 0.18 12.1 18.4 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein TSC22 PF01166.18 EAX89303.1 - 3.4 8.1 16.7 0.41 11.0 0.6 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family HrpB7 PF09486.10 EAX89303.1 - 3.5 8.0 15.5 8.3 6.8 0.3 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 EAX89303.1 - 4.5 6.3 39.1 0.15 11.1 14.8 2.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EAX89303.1 - 6.1 7.2 52.0 2.9 8.2 16.7 2.9 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) GPS2_interact PF15784.5 EAX89305.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX89305.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF2939 PF11159.8 EAX89307.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX89307.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PadR PF03551.14 EAX89308.1 - 0.07 13.1 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF4107 PF13389.6 EAX89311.1 - 1.9e-72 242.7 3.7 2.5e-72 242.4 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX89311.1 - 0.079 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX89312.1 - 3e-40 138.2 5.0 4.2e-40 137.7 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX89312.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster2 ZapB PF06005.12 EAX89312.1 - 0.2 12.1 0.9 1.1 9.8 0.2 2.3 2 1 1 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX89312.1 - 0.35 11.3 2.9 1.4 9.3 1.3 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Pox_A32 PF04665.12 EAX89313.1 - 6.7e-07 29.0 2.9 6.7e-07 29.0 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89313.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89313.1 - 5.2e-05 23.0 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89313.1 - 0.00012 22.1 2.8 0.0003 20.9 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89313.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89313.1 - 0.0012 18.7 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89313.1 - 0.0019 17.9 0.4 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89313.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89313.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89313.1 - 0.089 13.2 0.1 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89313.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89313.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX89315.1 - 3.5e-63 211.8 5.7 3.9e-63 211.6 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX89316.1 - 0.00028 21.3 2.9 0.0016 18.9 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Ank_2 PF12796.7 EAX89317.1 - 1.1e-39 134.9 2.6 9.5e-13 48.6 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89317.1 - 5.5e-37 125.7 0.7 8.3e-09 35.8 0.0 5.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX89317.1 - 1.8e-31 107.2 2.0 3.2e-07 30.5 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX89317.1 - 7.3e-31 105.8 2.2 4.8e-08 33.1 0.0 6.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89317.1 - 1.2e-27 92.8 0.6 0.0025 18.2 0.0 7.9 9 0 0 9 9 9 6 Ankyrin repeat Baculo_PEP_C PF04513.12 EAX89318.1 - 1.9e-05 24.7 12.2 1.9e-05 24.7 12.2 5.4 2 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.13 EAX89318.1 - 0.0012 18.6 4.6 0.0012 18.6 4.6 4.5 3 2 3 6 6 6 2 Nsp1-like C-terminal region DUF1664 PF07889.12 EAX89318.1 - 0.0091 16.0 4.7 0.0091 16.0 4.7 5.5 3 2 1 5 5 5 3 Protein of unknown function (DUF1664) DUF1974 PF09317.11 EAX89318.1 - 0.0099 15.5 1.2 0.0099 15.5 1.2 3.3 3 1 0 4 4 4 1 Domain of unknown function (DUF1974) Collagen_mid PF15984.5 EAX89318.1 - 0.53 10.0 4.5 11 5.8 0.7 2.5 1 1 0 2 2 2 0 Bacterial collagen, middle region DUF4455 PF14643.6 EAX89318.1 - 3.1 6.4 40.8 0.26 9.9 7.7 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4455) DUF3800 PF12686.7 EAX89318.1 - 3.9 8.1 8.0 1.3e+03 -0.0 8.0 3.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF3782 PF12644.7 EAX89318.1 - 4.3 7.6 11.6 0.82 9.9 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3782) Herpes_UL36 PF03586.13 EAX89320.1 - 0.04 13.2 0.7 0.047 13.0 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Lge1 PF11488.8 EAX89320.1 - 1 9.6 11.3 0.34 11.1 2.6 2.9 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 Microtub_bind PF13931.6 EAX89320.1 - 1 9.8 7.1 5.6 7.3 7.1 1.9 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding IBD PF10416.9 EAX89321.1 - 4.8e-27 94.5 0.4 5.9e-27 94.2 0.4 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Spo12 PF05032.12 EAX89322.1 - 5.5 7.0 12.1 0.17 11.8 2.9 2.6 4 0 0 4 4 4 0 Spo12 family Pkinase PF00069.25 EAX89323.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89323.1 - 4.2e-44 150.8 0.0 5.2e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX89323.1 - 5e-07 28.8 0.0 8.4e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX89323.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX89323.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PapD_N PF00345.20 EAX89324.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX89324.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX89325.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX89325.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX89326.1 - 0.0064 16.5 0.2 0.0086 16.1 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX89327.1 - 0.068 13.2 9.8 0.1 12.6 9.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX89328.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX89328.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MULE PF10551.9 EAX89329.1 - 2.5e-11 43.8 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX89329.1 - 0.0075 16.7 0.9 0.15 12.4 0.1 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5365) DUF4065 PF13274.6 EAX89329.1 - 0.065 14.1 0.4 1.7 9.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) FLYWCH PF04500.16 EAX89329.1 - 0.12 12.5 3.6 0.23 11.6 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain BTB PF00651.31 EAX89330.1 - 2.5e-06 27.7 0.0 6.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Vac_Fusion PF02346.16 EAX89330.1 - 1 9.1 7.2 0.74 9.5 0.2 3.4 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF1664 PF07889.12 EAX89330.1 - 2.3 8.3 7.1 2 8.5 2.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAX89330.1 - 5.1 7.3 9.9 1.1 9.4 4.7 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ThaI PF15514.6 EAX89331.1 - 0.019 14.6 0.2 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Restriction endonuclease ThaI Baculo_LEF-11 PF06385.12 EAX89331.1 - 7.8 7.1 9.0 0.87 10.1 0.6 3.3 3 0 0 3 3 3 0 Baculovirus LEF-11 protein Prefoldin PF02996.17 EAX89332.1 - 9.2e-23 80.4 7.0 1.2e-22 80.0 7.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin_2 PF14523.6 EAX89332.1 - 0.16 12.4 18.6 4.8 7.6 18.7 2.3 1 1 0 1 1 1 0 Syntaxin-like protein Methyltr_RsmF_N PF17125.5 EAX89332.1 - 0.2 12.2 0.1 0.2 12.2 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Erf4 PF10256.9 EAX89332.1 - 0.2 11.8 1.9 3.7 7.7 0.1 2.3 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Flavodoxin_2 PF02525.17 EAX89333.1 - 6e-23 81.6 0.1 8.2e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX89333.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase IPK PF03770.16 EAX89334.1 - 5.5e-35 121.0 0.0 7.8e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Phasin PF05597.11 EAX89335.1 - 0.002 18.1 2.6 0.002 18.1 2.6 4.3 2 2 3 5 5 5 1 Poly(hydroxyalcanoate) granule associated protein (phasin) TolA_bind_tri PF16331.5 EAX89335.1 - 0.026 14.6 7.8 0.026 14.6 7.8 6.8 2 2 3 6 6 6 0 TolA binding protein trimerisation ApbA_C PF08546.11 EAX89337.1 - 2.4e-25 89.2 0.1 7e-25 87.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EAX89337.1 - 8.1e-21 74.3 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EAX89337.1 - 0.0042 17.1 0.2 0.013 15.5 0.2 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EAX89337.1 - 0.0073 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EAX89337.1 - 0.045 14.3 0.0 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F5_F8_type_C PF00754.25 EAX89338.1 - 5.2e-07 29.8 0.1 2.7e-06 27.5 0.0 2.1 3 0 0 3 3 3 1 F5/8 type C domain PAX PF00292.18 EAX89338.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain TMEM154 PF15102.6 EAX89339.1 - 4.4e-05 23.4 5.9 6.1e-05 23.0 5.9 1.3 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 EAX89339.1 - 9.4e-05 22.7 0.9 0.00014 22.1 0.5 1.6 1 1 0 1 1 1 1 Orf78 (ac78) TMEM51 PF15345.6 EAX89339.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Sigma_reg_N PF13800.6 EAX89339.1 - 0.0013 19.0 0.4 0.0013 19.0 0.4 2.1 2 0 0 2 2 2 1 Sigma factor regulator N-terminal Chordopox_A13L PF05961.11 EAX89339.1 - 0.0021 18.3 0.9 0.0021 18.3 0.9 1.8 2 0 0 2 2 1 1 Chordopoxvirus A13L protein SieB PF14163.6 EAX89339.1 - 0.0023 17.5 0.4 0.23 10.9 0.1 2.1 2 0 0 2 2 2 1 Super-infection exclusion protein B DUF4064 PF13273.6 EAX89339.1 - 0.0025 18.1 5.6 0.046 14.0 0.4 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4064) Baculo_11_kDa PF06143.11 EAX89339.1 - 0.0039 16.7 0.4 0.0065 16.0 0.4 1.4 1 0 0 1 1 1 1 Baculovirus 11 kDa family Amnionless PF14828.6 EAX89339.1 - 0.01 14.7 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EAX89339.1 - 0.011 16.6 0.1 0.024 15.5 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 EAX89339.1 - 0.013 15.4 0.8 0.027 14.4 0.8 1.5 1 0 0 1 1 1 0 TMEM9 TadF PF16964.5 EAX89339.1 - 0.015 15.1 0.3 0.026 14.3 0.3 1.4 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Ly49 PF08391.10 EAX89339.1 - 0.02 15.3 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Shisa PF13908.6 EAX89339.1 - 0.021 15.1 2.6 0.026 14.8 0.9 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator RAMP PF04901.13 EAX89339.1 - 0.022 14.8 1.4 0.059 13.4 1.3 1.9 1 1 0 1 1 1 0 Receptor activity modifying family DUF2207 PF09972.9 EAX89339.1 - 0.024 13.4 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.12 EAX89339.1 - 0.027 14.4 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Ninjurin 7TM_GPCR_Srv PF10323.9 EAX89339.1 - 0.03 13.7 0.3 0.037 13.4 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SCIMP PF15050.6 EAX89339.1 - 0.034 14.6 0.2 0.034 14.6 0.2 1.7 2 0 0 2 2 2 0 SCIMP protein DUF4736 PF15883.5 EAX89339.1 - 0.039 13.7 0.2 0.06 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Phage_holin_6_1 PF09682.10 EAX89339.1 - 0.039 14.4 0.7 0.064 13.7 0.7 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4834 PF16118.5 EAX89339.1 - 0.04 14.9 0.4 0.04 14.9 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF4448 PF14610.6 EAX89339.1 - 0.041 13.6 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MAP17 PF15807.5 EAX89339.1 - 0.044 14.0 0.2 0.075 13.3 0.1 1.4 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Syndecan PF01034.20 EAX89339.1 - 0.048 13.6 0.4 0.082 12.8 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5385 PF17359.2 EAX89339.1 - 0.05 13.2 0.6 0.091 12.3 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Arc_PepC PF06819.11 EAX89339.1 - 0.051 13.7 1.5 0.1 12.7 1.5 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Peptidase_M56 PF05569.11 EAX89339.1 - 0.052 12.7 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3328 PF11807.8 EAX89339.1 - 0.083 12.6 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Tetraspanin PF00335.20 EAX89339.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Adipogenin PF15202.6 EAX89339.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Adipogenin DUF948 PF06103.11 EAX89339.1 - 0.15 12.3 1.9 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phospholamban PF04272.14 EAX89339.1 - 0.17 11.4 3.9 0.3 10.6 3.9 1.4 1 0 0 1 1 1 0 Phospholamban Presenilin PF01080.17 EAX89339.1 - 0.18 10.6 2.2 0.2 10.4 1.3 1.4 1 1 0 1 1 1 0 Presenilin DUF4381 PF14316.6 EAX89339.1 - 0.23 11.7 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GRP PF07172.11 EAX89339.1 - 0.25 12.0 0.3 0.86 10.3 0.1 1.8 2 0 0 2 2 2 0 Glycine rich protein family Insulin_TMD PF17870.1 EAX89339.1 - 0.33 11.1 3.7 0.64 10.1 3.7 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4711 PF15829.5 EAX89339.1 - 2 8.3 8.0 0.11 12.4 2.8 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4711) ASFV_J13L PF05568.11 EAX89339.1 - 2.4 7.8 7.5 0.87 9.3 4.0 1.8 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF3377 PF11857.8 EAX89339.1 - 5.2 7.1 14.0 0.29 11.1 7.8 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3377) LRR_5 PF13306.6 EAX89340.1 - 9.3e-74 245.5 61.8 3.2e-25 88.5 5.8 6.7 2 2 1 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89340.1 - 1.2e-09 37.8 5.8 0.67 9.8 0.0 9.6 8 3 4 12 12 12 3 Leucine rich repeat LRR_4 PF12799.7 EAX89340.1 - 0.001 19.4 20.8 11 6.5 0.4 9.7 7 4 2 9 9 9 1 Leucine Rich repeats (2 copies) Penaeidin PF05927.11 EAX89340.1 - 0.74 10.6 4.0 18 6.2 0.9 3.2 3 0 0 3 3 3 0 Penaeidin LRR_5 PF13306.6 EAX89341.1 - 3.5e-86 285.6 109.3 2.2e-20 72.9 8.2 7.2 2 2 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89341.1 - 1e-11 44.4 9.1 2.2e-05 24.1 0.0 7.7 5 2 3 8 8 8 3 Leucine rich repeat DUF3839 PF12943.7 EAX89342.1 - 1.5e-51 175.2 8.1 5.2e-43 147.3 1.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3839) SKG6 PF08693.10 EAX89344.1 - 2.5e-05 23.6 3.5 4.5e-05 22.8 3.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gly_rich PF12810.7 EAX89345.1 - 3.6e-38 131.8 37.4 4.7e-38 131.5 37.4 1.0 1 0 0 1 1 1 1 Glycine rich protein LMWPc PF01451.21 EAX89346.1 - 2.6e-22 79.7 0.0 2.9e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TTL PF03133.15 EAX89347.1 - 1.7e-62 211.2 0.4 2.7e-62 210.6 0.4 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX89347.1 - 5e-06 26.0 0.2 0.00052 19.3 0.1 2.7 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX89347.1 - 0.00033 20.0 0.0 0.0027 17.0 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX89347.1 - 0.00071 19.7 0.0 0.77 9.8 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 EAX89347.1 - 0.0029 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAX89347.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus TMEM214 PF10151.9 EAX89348.1 - 0.032 12.7 0.1 0.032 12.7 0.1 2.3 2 1 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 EAX89348.1 - 2.4 6.8 3.9 2.8 6.6 3.9 1.2 1 0 0 1 1 1 0 Presenilin LegC3_N PF18654.1 EAX89350.1 - 0.037 13.3 1.4 0.062 12.5 0.5 1.8 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain TMP PF05017.14 EAX89351.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89352.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX89353.1 - 8.9e-46 156.4 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89353.1 - 6e-16 58.5 0.0 8.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX89353.1 - 0.0027 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Cyclin_N PF00134.23 EAX89354.1 - 0.00019 21.2 0.1 0.0089 15.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Histone PF00125.24 EAX89355.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX89355.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX89355.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAX89356.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX89356.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX89356.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX89356.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain GIDA_assoc PF13932.6 EAX89357.1 - 0.011 16.0 2.5 0.014 15.6 2.5 1.1 1 0 0 1 1 1 0 GidA associated domain DUF2974 PF11187.8 EAX89357.1 - 0.071 12.7 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DASH_Dad3 PF08656.10 EAX89357.1 - 0.28 11.3 4.2 0.25 11.4 2.7 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 NYD-SP28_assoc PF14775.6 EAX89357.1 - 0.28 11.3 5.8 0.34 11.0 4.3 2.1 1 1 0 1 1 1 0 Sperm tail C-terminal domain DivIC PF04977.15 EAX89357.1 - 0.66 9.8 6.5 1.8 8.4 6.5 1.8 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 EAX89357.1 - 1 10.0 8.0 0.78 10.4 5.5 1.9 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EAX89357.1 - 6 7.4 13.2 1.3 9.5 8.5 2.3 2 2 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 EAX89358.1 - 2.3e-47 161.6 0.0 5.2e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89358.1 - 3.2e-32 111.8 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX89358.1 - 0.0047 16.3 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FmdA_AmdA PF03069.15 EAX89358.1 - 0.19 10.5 0.5 0.3 9.9 0.5 1.3 1 0 0 1 1 1 0 Acetamidase/Formamidase family Flavodoxin_2 PF02525.17 EAX89359.1 - 9.8e-34 116.8 0.1 1.2e-33 116.5 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX89359.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DUF1146 PF06612.11 EAX89360.1 - 0.045 13.8 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX89360.1 - 0.072 13.2 0.9 0.3 11.2 0.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Flavodoxin_2 PF02525.17 EAX89362.1 - 2.8e-34 118.5 0.1 3.4e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX89362.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Tetraspanin PF00335.20 EAX89363.1 - 0.0043 16.8 18.7 0.0072 16.1 18.7 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF1624 PF07786.12 EAX89363.1 - 0.24 10.9 6.3 0.44 10.1 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) ASFV_J13L PF05568.11 EAX89363.1 - 8.2 6.1 5.6 0.97 9.2 0.8 1.8 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF3839 PF12943.7 EAX89364.1 - 4.6e-157 520.7 12.6 5.7e-157 520.4 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89364.1 - 0.66 10.5 4.9 1.8 9.1 0.6 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX89365.1 - 6.2e-06 26.7 0.2 1.5e-05 25.4 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX89365.1 - 0.0044 16.6 0.3 0.16 11.5 0.1 2.1 2 0 0 2 2 2 2 Legume lectin domain Pox_A32 PF04665.12 EAX89366.1 - 3.7e-07 29.9 2.3 3.7e-07 29.9 2.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX89366.1 - 3.8e-05 23.5 0.3 0.36 10.6 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX89366.1 - 4.6e-05 23.7 0.2 0.00033 20.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX89366.1 - 0.00027 21.0 3.9 0.00058 19.9 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89366.1 - 0.00079 19.2 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89366.1 - 0.0013 18.6 0.6 0.0026 17.6 0.4 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89366.1 - 0.0037 16.9 2.5 0.012 15.3 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89366.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89366.1 - 0.091 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX89366.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX89366.1 - 0.11 12.5 0.6 1.5 8.8 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAX89366.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89366.1 - 0.48 10.7 4.0 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAX89366.1 - 0.66 10.7 11.2 0.35 11.5 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Peptidase_C97 PF05903.14 EAX89368.1 - 1.3e-14 54.3 0.4 1.8e-14 53.9 0.4 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 EAX89368.1 - 0.028 14.0 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) TraD_N PF12615.8 EAX89368.1 - 0.09 13.6 0.0 0.24 12.2 0.0 1.7 1 1 0 1 1 1 0 F sex factor protein N terminal PRK PF00485.18 EAX89369.1 - 0.0095 15.7 1.2 0.037 13.8 0.2 1.9 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family RecA PF00154.21 EAX89370.1 - 0.0028 17.2 0.0 0.0064 16.0 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein MeaB PF03308.16 EAX89370.1 - 0.0077 15.2 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 EAX89370.1 - 0.01 15.2 0.1 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 EAX89370.1 - 0.02 14.9 1.4 0.99 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAX89370.1 - 0.027 14.7 0.1 0.15 12.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EAX89370.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 EAX89370.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EAX89370.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 EAX89370.1 - 0.066 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAX89370.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 EAX89370.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EAX89370.1 - 0.2 11.2 0.1 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PARM PF17061.5 EAX89371.1 - 0.67 10.0 19.9 0.93 9.6 19.9 1.3 1 0 0 1 1 1 0 PARM PSP PF04046.16 EAX89372.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DDR PF08841.10 EAX89375.1 - 0.083 11.9 0.1 0.084 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX89375.1 - 0.087 13.3 1.3 0.11 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX89376.1 - 0.081 12.9 11.3 0.13 12.3 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amidase02_C PF12123.8 EAX89378.1 - 0.012 15.3 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX89379.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_2 PF12796.7 EAX89382.1 - 1.9e-17 63.6 0.0 3.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89382.1 - 7.1e-12 45.2 0.0 0.00012 22.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX89382.1 - 1.5e-10 40.4 0.0 0.00027 21.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX89382.1 - 1.8e-10 41.1 0.0 4e-06 27.3 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89382.1 - 1.8e-09 37.6 0.0 0.00013 22.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Gp-FAR-1 PF05823.12 EAX89384.1 - 0.092 13.1 0.2 11 6.4 0.1 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TIR_2 PF13676.6 EAX89384.1 - 0.12 13.0 0.0 0.41 11.2 0.0 1.9 1 1 0 1 1 1 0 TIR domain DUF1748 PF08520.10 EAX89385.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) LRR_5 PF13306.6 EAX89386.1 - 5.2e-98 323.9 99.6 3.5e-21 75.5 4.4 6.2 3 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89386.1 - 3.3e-14 52.4 9.4 0.0062 16.3 0.1 9.2 7 3 4 11 11 11 5 Leucine rich repeat MecA PF05389.12 EAX89386.1 - 0.0015 18.2 1.9 0.0031 17.2 1.9 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) LRR_4 PF12799.7 EAX89386.1 - 0.046 14.2 17.8 0.31 11.5 0.2 6.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAX89386.1 - 0.35 11.1 2.9 30 4.9 0.0 3.9 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) TACC_C PF05010.14 EAX89387.1 - 2.8e-05 24.0 12.8 2.8e-05 24.0 12.8 3.4 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AIP3 PF03915.13 EAX89387.1 - 0.0012 18.1 18.3 0.0012 18.1 18.3 2.4 1 1 1 2 2 2 1 Actin interacting protein 3 DUF1664 PF07889.12 EAX89387.1 - 1.3 9.0 34.6 0.88 9.6 4.9 4.7 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EAX89387.1 - 1.7 6.1 46.7 0.52 7.8 21.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Halo_GVPC PF05465.13 EAX89387.1 - 2.6 8.4 6.7 17 5.8 0.1 4.1 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Baculo_PEP_C PF04513.12 EAX89387.1 - 5.4 7.1 29.2 0.63 10.1 5.2 4.3 1 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus EIF4E-T PF10477.9 EAX89387.1 - 9 5.0 24.4 11 4.6 24.4 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E EXOSC1 PF10447.9 EAX89388.1 - 5.1e-07 30.3 0.5 0.031 14.9 0.0 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 TRAM PF01938.20 EAX89388.1 - 0.00056 19.9 3.2 0.0062 16.5 0.0 2.6 3 0 0 3 3 3 1 TRAM domain HAD PF12710.7 EAX89388.1 - 0.047 14.1 0.0 0.052 14.0 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4020 PF13212.6 EAX89389.1 - 1.5 8.6 5.9 76 3.1 0.1 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4020) T5orf172 PF10544.9 EAX89390.1 - 1.5e-06 28.7 0.2 3.4e-06 27.5 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX89390.1 - 0.0059 16.4 0.1 0.042 13.7 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX89390.1 - 0.051 13.1 1.3 0.36 10.3 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX89391.1 - 4.2e-35 120.0 0.5 9.1e-35 118.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX89391.1 - 0.052 14.2 0.0 0.15 12.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX89392.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89392.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89392.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89392.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89392.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89392.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89392.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89392.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89392.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89392.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89392.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89392.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX89393.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX89394.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4378 PF14309.6 EAX89395.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) Fib_alpha PF08702.10 EAX89396.1 - 2.7 8.2 27.9 0.025 14.8 16.4 3.0 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Zip PF02535.22 EAX89396.1 - 8.9 5.4 5.6 11 5.1 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HAP1_N PF04849.13 EAX89397.1 - 0.0061 15.8 9.5 0.0061 15.8 9.5 3.8 1 1 3 4 4 4 2 HAP1 N-terminal conserved region Atg14 PF10186.9 EAX89397.1 - 1.1 8.2 62.8 0.032 13.3 20.0 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A_type_inc PF04508.12 EAX89397.1 - 1.5 8.8 6.8 19 5.3 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF812 PF05667.11 EAX89397.1 - 1.5 7.6 61.0 0.042 12.7 12.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EAX89397.1 - 2.2 8.4 71.3 2.5 8.2 10.0 4.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAX89397.1 - 3.4 7.7 57.7 0.079 13.0 24.4 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EAX89397.1 - 3.9 6.3 63.6 2.6 6.9 27.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Calici_coat_C PF08435.11 EAX89398.1 - 0.0044 16.6 0.4 0.005 16.4 0.4 1.1 1 0 0 1 1 1 1 Calicivirus coat protein C-terminal SAPS PF04499.15 EAX89400.1 - 0.46 9.2 4.8 0.14 10.9 1.2 1.9 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Ras PF00071.22 EAX89402.1 - 1.2e-32 112.8 0.1 1.3e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89402.1 - 2.6e-28 98.7 0.0 2.9e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89402.1 - 1.6e-10 40.8 0.0 1.8e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX89402.1 - 3.8e-05 23.1 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX89402.1 - 0.00026 21.0 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX89402.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX89402.1 - 0.0026 17.3 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 EAX89402.1 - 0.012 15.2 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAX89402.1 - 0.035 14.5 0.0 0.046 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAX89402.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 EAX89402.1 - 0.054 12.9 0.0 0.063 12.7 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EAX89402.1 - 0.06 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 EAX89402.1 - 0.079 12.1 0.1 0.45 9.6 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 EAX89402.1 - 0.091 12.5 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAX89402.1 - 0.16 11.1 0.0 3.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EAX89402.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DUF3839 PF12943.7 EAX89403.1 - 4.4e-155 514.2 14.2 5.5e-155 513.9 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX89403.1 - 0.021 15.1 0.8 1.5 9.1 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX89403.1 - 0.17 11.7 1.8 0.45 10.4 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX89403.1 - 0.42 11.1 6.4 1.9 9.0 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX89403.1 - 0.46 11.1 3.8 1.1 9.9 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KilA-N PF04383.13 EAX89404.1 - 3.1e-36 123.6 1.6 3.7e-36 123.4 0.3 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX89404.1 - 0.011 16.3 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family LOH1CR12 PF10158.9 EAX89404.1 - 0.28 11.2 4.7 1.9 8.5 0.5 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Pox_A32 PF04665.12 EAX89405.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89405.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89405.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89405.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89405.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89405.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89405.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89405.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89405.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89405.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89405.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89405.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Myb_DNA-binding PF00249.31 EAX89407.1 - 2.3e-23 82.1 0.3 9.1e-14 51.4 0.5 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89407.1 - 1.2e-16 60.6 3.4 4e-12 46.2 0.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89407.1 - 0.00021 21.1 5.3 0.0091 15.9 0.2 2.7 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX89407.1 - 0.062 13.3 3.8 7.4 6.6 0.1 3.1 2 1 1 3 3 3 0 SLIDE eIF-4B PF06273.11 EAX89407.1 - 0.19 10.7 0.9 0.21 10.6 0.3 1.3 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B FGGY_N PF00370.21 EAX89408.1 - 3.1e-31 108.8 0.4 1.5e-17 64.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 EAX89408.1 - 0.00051 19.6 0.4 0.74 9.2 0.1 2.4 2 0 0 2 2 2 2 ROK family OTU PF02338.19 EAX89409.1 - 5.2e-05 23.7 0.1 9.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C3HC PF07967.13 EAX89409.1 - 0.045 13.8 0.5 0.088 12.8 0.1 1.6 2 0 0 2 2 2 0 C3HC zinc finger-like HalOD2 PF18547.1 EAX89409.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Halobacterial output domain 2 LRR_5 PF13306.6 EAX89411.1 - 4.2e-80 266.0 94.3 3.4e-19 69.1 4.9 9.1 3 2 7 10 10 10 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89411.1 - 5.1e-07 29.4 9.0 0.37 10.6 0.0 7.9 5 2 2 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 EAX89411.1 - 6.9e-05 23.1 28.6 2.5 8.6 0.0 10.1 7 3 2 9 9 9 3 Leucine Rich repeats (2 copies) Insulin_TMD PF17870.1 EAX89411.1 - 9.5 6.4 6.4 24 5.1 6.4 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment GPS2_interact PF15784.5 EAX89412.1 - 0.047 14.1 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Collagen_bind_2 PF12904.7 EAX89413.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase zf-C3HC4_3 PF13920.6 EAX89417.1 - 0.089 12.7 1.6 0.24 11.3 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 EAX89417.1 - 0.21 11.2 2.0 0.5 10.0 2.0 1.6 1 0 0 1 1 1 0 RecR protein zf-FPG_IleRS PF06827.14 EAX89417.1 - 0.32 10.9 2.8 0.7 9.8 2.8 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS ARA70 PF12489.8 EAX89418.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX89419.1 - 5.3e-05 22.8 2.8 6.6e-05 22.5 1.9 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX89419.1 - 0.005 16.9 0.9 0.011 15.7 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX89419.1 - 0.041 13.1 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MetOD2 PF18548.1 EAX89422.1 - 0.032 14.3 1.0 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 Dzip-like_N PF13815.6 EAX89423.1 - 7.9e-11 42.0 0.3 7.9e-11 42.0 0.3 2.3 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Rad50_zn_hook PF04423.14 EAX89423.1 - 0.016 15.1 0.2 0.016 15.1 0.2 2.9 3 1 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 EAX89423.1 - 0.021 15.6 0.9 0.049 14.5 0.9 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 EAX89423.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAX89423.1 - 0.24 12.0 1.4 0.48 11.0 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type MADF_DNA_bdg PF10545.9 EAX89423.1 - 2.2 8.7 6.9 1.2 9.6 0.8 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 EAX89424.1 - 5.8e-34 116.0 0.6 3.6e-17 62.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89424.1 - 2.6e-28 98.0 2.7 4.5e-18 65.3 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89424.1 - 3.2e-07 30.1 1.4 0.00022 21.1 0.3 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX89424.1 - 9.8e-06 25.6 0.3 0.089 12.8 0.0 3.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX89424.1 - 0.0026 17.9 2.2 1.4 9.2 0.1 3.5 1 1 1 2 2 2 2 Rap1 Myb domain GIY-YIG PF01541.24 EAX89424.1 - 0.026 14.8 0.3 0.062 13.6 0.3 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain SANT_DAMP1_like PF16282.5 EAX89424.1 - 0.089 13.0 0.3 0.82 9.9 0.0 2.4 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX89424.1 - 0.16 12.4 5.1 0.62 10.5 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ank_5 PF13857.6 EAX89425.1 - 6.1e-40 134.8 0.4 1e-12 48.0 0.2 5.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89425.1 - 3.2e-36 123.8 1.1 1.6e-16 60.7 0.0 4.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89425.1 - 7.3e-29 96.6 0.1 6.8e-05 23.0 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EAX89425.1 - 1.9e-27 94.4 0.0 4.1e-06 27.0 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EAX89425.1 - 2.2e-27 95.1 0.1 6.6e-08 32.9 0.1 7.2 3 1 5 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89425.1 - 3e-14 52.7 4.8 3e-14 52.7 4.8 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) NIF PF03031.18 EAX89426.1 - 8e-43 145.9 0.3 9.4e-43 145.7 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PNK3P PF08645.11 EAX89426.1 - 0.065 12.9 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.26 EAX89426.1 - 0.088 13.1 0.0 12 6.2 0.1 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EAX89426.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_C97 PF05903.14 EAX89427.1 - 1.4e-20 73.7 0.8 1.7e-20 73.3 0.8 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EAX89427.1 - 0.07 13.4 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Bombolitin PF08096.11 EAX89428.1 - 0.15 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Bombolitin family Ank_2 PF12796.7 EAX89429.1 - 1.1e-49 167.0 28.8 9.7e-09 35.7 0.2 11.3 5 4 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89429.1 - 5.3e-38 128.9 20.0 8.3e-05 23.1 0.0 14.7 9 4 5 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89429.1 - 2.5e-29 98.0 29.8 0.59 10.9 0.0 18.8 19 1 0 19 19 19 11 Ankyrin repeat Ank_5 PF13857.6 EAX89429.1 - 1.3e-21 76.4 17.8 0.0027 18.0 0.0 12.0 12 3 2 14 14 14 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX89429.1 - 1.2e-20 72.9 18.6 0.42 11.2 0.1 15.0 14 2 0 14 14 14 6 Ankyrin repeat Big_7 PF17957.1 EAX89430.1 - 1.2e-08 35.6 25.3 0.0015 19.3 0.2 6.8 6 1 1 7 7 7 2 Bacterial Ig domain Alph_Pro_TM PF09608.10 EAX89430.1 - 0.0014 18.5 0.0 4.3 7.1 0.0 3.8 4 0 0 4 4 4 1 Putative transmembrane protein (Alph_Pro_TM) DUF4625 PF15418.6 EAX89430.1 - 0.03 14.6 0.6 0.03 14.6 0.6 6.4 4 1 2 8 8 8 0 Domain of unknown function (DUF4625) Porphobil_deamC PF03900.15 EAX89430.1 - 0.13 12.7 0.2 12 6.4 0.0 3.8 5 0 0 5 5 5 0 Porphobilinogen deaminase, C-terminal domain CBM_3 PF00942.18 EAX89430.1 - 1.4 9.4 17.2 0.19 12.2 0.6 4.7 5 0 0 5 5 5 0 Cellulose binding domain DUF2326 PF10088.9 EAX89430.1 - 1.9 8.2 11.6 6.4 6.5 0.0 4.6 3 1 3 6 6 6 0 Uncharacterised protein conserved in bacteria (DUF2326) HCBP_related PF06594.11 EAX89430.1 - 3.4 7.7 6.8 4.4 7.3 0.1 4.0 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Ank_3 PF13606.6 EAX89431.1 - 2.9e-08 33.3 0.2 0.22 12.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX89431.1 - 3.1e-08 34.1 0.0 0.0044 17.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89431.1 - 0.00012 22.3 0.3 1.3 9.6 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX89431.1 - 0.005 17.4 0.1 0.34 11.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89431.1 - 0.048 14.0 0.5 11 6.5 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) FMN_red PF03358.15 EAX89434.1 - 9.9e-16 57.9 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAX89434.1 - 9.2e-10 38.6 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EAX89434.1 - 0.0012 19.1 0.0 0.0083 16.4 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin domain Fer4_20 PF14691.6 EAX89434.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.7 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster PSP PF04046.16 EAX89435.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89436.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PRA-PH PF01503.17 EAX89438.1 - 0.45 11.0 3.6 13 6.3 3.3 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase TRAPPC9-Trs120 PF08626.11 EAX89439.1 - 3e-07 28.2 1.9 0.0025 15.3 0.1 3.1 3 0 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3447 PF11929.8 EAX89440.1 - 1.4e-40 137.1 6.5 1.4e-40 137.1 6.5 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89440.1 - 0.00042 20.8 0.1 0.00094 19.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PRA-PH PF01503.17 EAX89441.1 - 0.39 11.2 2.9 13 6.3 3.3 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF3839 PF12943.7 EAX89442.1 - 1.8e-156 518.7 12.6 2.3e-156 518.4 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89442.1 - 1.1 9.7 5.7 2.5 8.6 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Homeobox_KN PF05920.11 EAX89444.1 - 5.3e-16 58.2 0.7 9.5e-16 57.4 0.7 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAX89444.1 - 2.5e-11 43.3 0.4 4.2e-11 42.5 0.4 1.3 1 0 0 1 1 1 1 Homeodomain Myb_DNA-binding PF00249.31 EAX89446.1 - 1.9e-23 82.4 0.6 8.9e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89446.1 - 1.1e-15 57.6 7.2 4.1e-11 43.0 1.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89446.1 - 0.0059 16.6 1.2 0.03 14.3 0.7 2.1 1 1 1 2 2 2 1 SLIDE MADF_DNA_bdg PF10545.9 EAX89446.1 - 0.011 16.0 8.4 0.21 11.9 0.3 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 EAX89446.1 - 0.039 14.1 1.9 0.4 10.9 0.3 2.7 1 1 1 2 2 2 0 Rap1 Myb domain Halogen_Hydrol PF10112.9 EAX89446.1 - 0.041 13.9 1.1 0.055 13.5 1.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Myb_DNA-bind_4 PF13837.6 EAX89446.1 - 0.35 11.3 10.8 0.5 10.8 1.6 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EAX89447.1 - 1.8e-59 201.3 0.0 2.5e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89447.1 - 1.4e-42 145.8 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89447.1 - 1.6e-09 37.5 0.0 5.3e-09 35.8 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EAX89447.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EAX89447.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX89447.1 - 0.066 13.1 0.0 0.89 9.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX89447.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family T4SS_CagC PF16943.5 EAX89448.1 - 0.002 18.3 0.4 0.0053 16.9 0.3 1.7 2 0 0 2 2 2 1 Cag pathogenicity island, type IV secretory system DUF4690 PF15756.5 EAX89448.1 - 0.0045 17.6 0.3 0.0082 16.7 0.3 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 EAX89448.1 - 0.019 15.0 3.1 0.019 15.0 3.1 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF3042 PF11240.8 EAX89448.1 - 0.028 14.4 0.4 0.062 13.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Podoplanin PF05808.11 EAX89448.1 - 0.13 12.3 0.4 0.2 11.8 0.4 1.2 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EAX89448.1 - 0.15 10.9 0.5 0.2 10.5 0.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_hydro_47 PF01532.20 EAX89450.1 - 1.4e-46 159.4 3.4 1.8e-26 93.1 0.7 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 PAP2 PF01569.21 EAX89451.1 - 4.4e-10 39.5 6.1 4.4e-10 39.5 6.1 2.3 1 1 1 2 2 2 1 PAP2 superfamily DUF543 PF04418.12 EAX89451.1 - 0.064 13.2 0.7 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) RseC_MucC PF04246.12 EAX89451.1 - 0.92 9.5 3.8 0.42 10.6 0.8 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3829 PF12889.7 EAX89452.1 - 6.9e-05 22.5 1.3 0.0001 21.9 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) DUF2070 PF09843.9 EAX89453.1 - 0.32 9.2 12.1 0.49 8.6 12.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1664 PF07889.12 EAX89455.1 - 0.0026 17.8 53.1 0.21 11.7 2.8 5.9 4 2 1 5 5 5 4 Protein of unknown function (DUF1664) CEP63 PF17045.5 EAX89455.1 - 0.0026 17.7 25.5 0.0026 17.7 25.5 3.2 2 1 0 2 2 2 1 Centrosomal protein of 63 kDa YkyA PF10368.9 EAX89455.1 - 0.0074 16.0 33.3 0.0074 16.0 33.3 4.6 2 1 3 5 5 5 2 Putative cell-wall binding lipoprotein ATG16 PF08614.11 EAX89455.1 - 0.015 15.6 24.9 0.015 15.6 24.9 4.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 EAX89455.1 - 0.09 10.9 65.9 0.058 11.5 28.6 2.6 1 1 1 2 2 2 0 HOOK protein Spc7 PF08317.11 EAX89455.1 - 0.15 10.9 76.4 0.034 13.0 23.4 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein ADIP PF11559.8 EAX89455.1 - 0.19 11.8 71.7 0.11 12.6 20.2 5.0 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 EAX89455.1 - 1.1 8.7 65.3 0.18 11.4 47.1 3.8 1 1 2 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 EAX89455.1 - 1.8 7.8 51.0 0.24 10.7 21.9 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4686 PF15742.5 EAX89455.1 - 2.2 7.3 71.4 1.9 7.6 33.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Pox_A_type_inc PF04508.12 EAX89455.1 - 2.8 8.0 10.6 4.6 7.2 0.0 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Lebercilin PF15619.6 EAX89455.1 - 3.5 7.3 69.6 3.4 7.3 9.4 4.5 2 2 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease HrpB7 PF09486.10 EAX89455.1 - 6.7 7.1 18.8 2.5 8.5 1.5 3.8 3 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Nitroreductase PF00881.24 EAX89456.1 - 2.9e-29 102.3 0.0 3.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX89456.1 - 0.0022 17.6 1.4 3.7 7.1 0.0 2.9 1 1 2 3 3 3 3 Putative TM nitroreductase Peptidase_C12 PF01088.21 EAX89457.1 - 1.2e-42 146.0 0.0 1.5e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TPR_1 PF00515.28 EAX89458.1 - 2.4e-05 24.0 5.3 0.0098 15.7 0.0 4.6 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX89458.1 - 0.0011 18.9 4.9 0.084 13.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat GerD PF17898.1 EAX89458.1 - 0.18 11.7 1.4 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain Ldh_1_N PF00056.23 EAX89459.1 - 2.6e-27 95.6 0.0 4.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX89459.1 - 1.7e-20 73.7 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX89459.1 - 0.054 13.7 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Pkinase PF00069.25 EAX89460.1 - 3.6e-58 197.0 0.0 4.2e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89460.1 - 4.4e-43 147.4 0.0 5.2e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89460.1 - 9.5e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX89460.1 - 0.001 18.2 0.2 0.0016 17.5 0.2 1.3 1 1 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAX89460.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX89460.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 EAX89461.1 - 1.4e-49 166.6 0.1 3.2e-17 62.9 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89461.1 - 2.2e-30 104.6 0.3 2.7e-09 37.4 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89461.1 - 5.5e-27 93.0 0.0 1.1e-05 25.7 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX89461.1 - 1.2e-22 79.7 0.3 2.1e-07 31.1 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89461.1 - 1e-21 74.7 0.0 0.00012 22.2 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat ThiF PF00899.21 EAX89462.1 - 9.5e-53 179.0 0.0 2.4e-48 164.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family DD_K PF12121.8 EAX89462.1 - 0.18 11.9 2.0 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Dermaseptin UBA_e1_thiolCys PF10585.9 EAX89463.1 - 4.3e-50 171.0 0.6 6.9e-50 170.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EAX89463.1 - 1.4e-15 57.8 0.2 2.9e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain ThiF PF00899.21 EAX89463.1 - 5e-08 32.6 0.0 2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 ThiF family C4 PF01413.19 EAX89463.1 - 0.067 13.6 0.3 0.81 10.1 0.5 2.3 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen Ank_2 PF12796.7 EAX89464.1 - 7e-09 36.2 0.0 1.1e-08 35.5 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89464.1 - 1.3e-07 32.0 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89464.1 - 3.2e-07 30.5 0.0 6.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89464.1 - 1.2e-05 25.2 0.0 0.0039 17.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAX89464.1 - 0.00036 20.8 0.0 0.094 13.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat ComA PF02679.15 EAX89465.1 - 0.077 12.5 1.5 0.09 12.2 1.5 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX89465.1 - 0.18 11.2 0.5 0.32 10.4 0.5 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PRD PF00874.20 EAX89465.1 - 0.79 10.1 5.2 4.3 7.7 0.5 2.3 1 1 2 3 3 3 0 PRD domain Sipho_Gp157 PF05565.11 EAX89466.1 - 0.056 13.5 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Beta_helix PF13229.6 EAX89467.1 - 0.33 10.8 7.0 0.058 13.2 2.0 2.1 2 0 0 2 2 2 0 Right handed beta helix region Ank_4 PF13637.6 EAX89468.1 - 8.8e-109 354.6 30.2 1.7e-12 47.5 0.2 13.8 4 3 11 15 15 15 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89468.1 - 8.2e-93 305.1 56.4 7.4e-20 71.3 4.7 8.1 2 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89468.1 - 3.1e-88 286.7 22.6 1.3e-07 31.8 0.0 12.4 12 0 0 12 12 12 12 Ankyrin repeat Ank_3 PF13606.6 EAX89468.1 - 4.4e-70 223.3 22.2 7.9e-06 25.8 0.0 13.2 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 EAX89468.1 - 9.6e-64 210.6 33.5 2.7e-10 40.3 0.1 9.0 4 2 6 10 10 10 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89468.1 - 3.2e-37 126.3 8.0 1.8e-36 123.9 8.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX89468.1 - 7e-05 22.9 24.0 17 5.7 0.2 10.1 6 3 5 11 11 11 1 Protein of unknown function (DUF3718) DUF756 PF05506.12 EAX89468.1 - 0.36 11.8 6.6 1.2e+02 3.7 1.0 5.9 1 1 1 2 2 2 0 Domain of unknown function (DUF756) YDG PF18657.1 EAX89468.1 - 0.52 10.5 3.9 12 6.2 0.1 3.8 2 2 2 4 4 4 0 YDG domain IBD PF10416.9 EAX89470.1 - 8.3e-20 71.1 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Glucokinase PF02685.16 EAX89471.1 - 1.5e-23 83.3 0.0 2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EAX89471.1 - 1.1e-05 25.0 0.0 0.037 13.5 0.0 2.5 2 1 0 2 2 2 2 ROK family DUF4107 PF13389.6 EAX89475.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Gly-zipper_Omp PF13488.6 EAX89478.1 - 0.035 14.1 11.2 0.046 13.7 11.2 1.2 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX89478.1 - 0.19 12.0 3.9 0.34 11.2 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) ActA PF05058.12 EAX89478.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein PT-VENN PF04829.13 EAX89478.1 - 1.3 9.2 5.7 2 8.6 5.6 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX89478.1 - 3 8.9 0.2 3 8.9 0.2 3.3 4 0 0 4 4 4 0 TMP repeat Ank_2 PF12796.7 EAX89479.1 - 1.9e-28 98.9 2.2 5.2e-14 52.6 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89479.1 - 4e-20 71.6 1.3 9e-06 25.9 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89479.1 - 1.5e-16 58.8 0.3 0.0038 17.6 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX89479.1 - 3e-14 53.2 0.4 1.2e-06 28.9 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX89479.1 - 1.9e-12 47.0 2.2 1.7e-05 25.1 0.4 4.9 5 0 0 5 5 5 3 Ankyrin repeat 14-3-3 PF00244.20 EAX89480.1 - 4.2e-70 235.7 6.1 4.7e-70 235.5 6.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 EAX89480.1 - 0.00021 21.3 1.2 0.84 10.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat CAMP_factor PF07373.11 EAX89480.1 - 0.025 14.2 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) FadA PF09403.10 EAX89481.1 - 7.6 7.1 10.2 0.2 12.1 1.6 2.9 2 0 0 2 2 2 0 Adhesion protein FadA DUF3447 PF11929.8 EAX89482.1 - 3.3e-38 129.5 16.6 3.1e-37 126.4 4.1 4.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89482.1 - 1.2e-26 93.1 1.9 1.6e-10 41.4 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89482.1 - 9.3e-16 58.0 0.2 7.7e-05 23.2 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89482.1 - 1.9e-09 36.9 0.1 0.17 12.6 0.0 6.1 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX89482.1 - 9.2e-09 35.4 0.0 0.058 13.7 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX89482.1 - 1.5e-07 31.6 0.0 0.036 14.5 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat PSP PF04046.16 EAX89484.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89485.1 - 0.068 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX89486.1 - 0.022 15.2 0.6 0.046 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89487.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.9 3 0 0 3 3 3 1 Phage tail repeat like Kinetochor_Ybp2 PF08568.10 EAX89487.1 - 0.063 11.7 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin YmaF PF12788.7 EAX89487.1 - 0.22 12.1 2.6 1.4 9.5 1.0 2.6 2 1 0 2 2 2 0 YmaF family TMP PF05017.14 EAX89488.1 - 0.068 13.8 5.6 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89489.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TCTP PF00838.17 EAX89490.1 - 0.11 12.8 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Translationally controlled tumour protein TPR_6 PF13174.6 EAX89492.1 - 4.2e-09 36.5 2.6 0.2 12.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX89492.1 - 1.6e-07 31.7 1.1 0.25 11.9 0.0 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX89492.1 - 2.7e-06 27.5 6.6 0.002 18.3 0.1 5.5 4 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EAX89492.1 - 7.3e-06 25.7 14.5 1.4 9.3 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX89492.1 - 2.4e-05 24.8 0.2 3.4 8.7 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX89492.1 - 2.5e-05 24.0 1.6 21 5.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAX89492.1 - 4e-05 23.5 17.0 2.1 8.8 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX89492.1 - 0.00011 22.4 10.3 17 5.8 0.0 6.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAX89492.1 - 0.00028 21.4 1.4 34 5.2 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAX89492.1 - 0.00094 18.8 6.5 0.042 13.5 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 EAX89492.1 - 0.0011 18.6 12.6 0.37 10.7 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 EAX89492.1 - 0.011 15.9 0.0 13 6.3 0.0 4.2 3 0 0 3 3 3 0 PPR repeat SRP_TPR_like PF17004.5 EAX89492.1 - 0.044 13.8 3.8 0.19 11.7 0.3 3.1 2 1 0 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 EAX89492.1 - 0.2 11.7 1.2 9.5 6.4 0.0 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EAX89492.1 - 3.4 8.3 6.5 65 4.2 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAX89492.1 - 7.9 6.5 10.6 23 5.0 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX89493.1 - 0.00017 22.2 4.4 0.051 14.4 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX89493.1 - 0.00019 21.3 5.9 0.13 12.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX89493.1 - 0.00026 21.0 2.5 0.18 12.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX89493.1 - 0.00068 20.2 6.6 0.6 10.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX89493.1 - 0.016 15.2 1.8 3.3 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAX89493.1 - 0.019 15.5 3.5 0.079 13.5 0.7 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAX89493.1 - 0.071 13.3 0.7 0.13 12.4 0.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAX89493.1 - 0.11 12.3 2.3 17 5.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 EAX89494.1 - 1.2e-42 143.7 7.2 1.4e-12 47.9 0.0 7.1 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX89494.1 - 2.8e-39 131.9 6.1 5e-08 33.0 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_2 PF12796.7 EAX89494.1 - 7.7e-39 132.2 17.3 1.4e-14 54.4 1.2 5.6 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX89494.1 - 9.4e-36 121.6 5.2 9.4e-36 121.6 5.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX89494.1 - 2.2e-35 116.7 7.4 4.4e-06 26.6 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX89494.1 - 2.8e-25 88.1 2.2 2.5e-11 43.6 0.1 4.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) CCDC84 PF14968.6 EAX89494.1 - 0.046 13.3 2.7 0.13 11.8 2.7 1.7 1 1 0 1 1 1 0 Coiled coil protein 84 RL PF17797.1 EAX89494.1 - 0.069 13.1 7.4 3.3 7.7 0.0 5.2 5 1 0 5 5 5 0 RL domain Ribosomal_60s PF00428.19 EAX89495.1 - 8.8e-05 23.0 7.6 0.00019 22.0 7.6 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 EAX89495.1 - 0.21 12.2 3.8 0.17 12.6 1.2 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) zf-C2HC_2 PF13913.6 EAX89497.1 - 2.6e-16 59.1 12.7 2e-10 40.3 1.9 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CHCC PF10276.9 EAX89497.1 - 0.00039 20.4 1.2 0.92 9.6 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2 PF00096.26 EAX89497.1 - 0.00077 19.8 0.6 2.3 8.9 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type YacG PF03884.14 EAX89497.1 - 0.0028 17.3 1.5 0.0072 16.0 1.5 1.7 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG SAM_2 PF07647.17 EAX89497.1 - 0.0034 17.4 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rad50_zn_hook PF04423.14 EAX89497.1 - 0.0038 17.0 0.5 0.0038 17.0 0.5 2.1 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 EAX89497.1 - 0.036 14.9 3.5 5.2 8.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAX89497.1 - 0.081 13.4 0.5 4.4 7.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain DUF2256 PF10013.9 EAX89497.1 - 0.09 12.9 1.7 15 5.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 EAX89497.1 - 0.14 11.9 2.8 5.6 6.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF3039 PF11238.8 EAX89497.1 - 1 9.1 5.1 7.1 6.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) ATP11 PF06644.11 EAX89498.1 - 0.01 15.7 1.6 0.013 15.3 1.6 1.1 1 0 0 1 1 1 1 ATP11 protein Bromodomain PF00439.25 EAX89499.1 - 2.9e-12 46.5 3.0 7.5e-12 45.2 3.0 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 EAX89499.1 - 1.1e-05 25.4 0.1 2.6e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX89499.1 - 0.00022 21.6 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAX89499.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TFIIS_M PF07500.14 EAX89499.1 - 0.033 14.7 0.5 0.068 13.7 0.1 1.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Nbl1_Borealin_N PF10444.9 EAX89500.1 - 3e-16 58.8 0.0 5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal LTP_2 PF14368.6 EAX89500.1 - 0.12 12.5 0.4 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Probable lipid transfer DUF2407_C PF13373.6 EAX89501.1 - 2.5e-07 31.0 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EAX89501.1 - 4.7e-05 23.1 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX89501.1 - 0.00046 20.0 0.2 0.00046 20.0 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 EAX89501.1 - 0.0028 17.8 0.0 0.0058 16.8 0.0 1.5 1 1 0 1 1 1 1 UBX domain Rad60-SLD_2 PF13881.6 EAX89501.1 - 0.028 14.5 0.0 0.066 13.3 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ank_2 PF12796.7 EAX89502.1 - 8.6e-07 29.5 0.0 0.0032 18.0 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89502.1 - 0.00049 20.3 0.4 1.9 9.3 0.0 4.4 3 1 1 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EAX89502.1 - 0.0015 19.1 0.3 5.1 7.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89502.1 - 0.0024 17.8 3.1 0.0024 17.8 3.1 3.2 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX89502.1 - 0.14 12.6 0.0 25 5.5 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat DUF3839 PF12943.7 EAX89503.1 - 6.3e-149 494.1 11.5 7.7e-149 493.8 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89503.1 - 0.1 13.1 3.4 1.3 9.6 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Muted PF14942.6 EAX89505.1 - 0.049 14.0 0.2 0.051 13.9 0.2 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PTR PF12789.7 EAX89507.1 - 2.8e-52 174.6 37.1 2.8e-32 110.6 15.8 4.9 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX89507.1 - 0.035 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Adaptin_N PF01602.20 EAX89509.1 - 2e-71 241.1 17.1 2.6e-71 240.8 17.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EAX89509.1 - 0.00016 21.9 2.0 0.00022 21.5 0.4 2.2 1 1 1 2 2 2 1 Adaptin C-terminal domain CheX PF13690.6 EAX89509.1 - 0.43 10.8 2.4 1.9 8.7 0.3 2.9 4 0 0 4 4 4 0 Chemotaxis phosphatase CheX PEP-utilizers_C PF02896.18 EAX89510.1 - 2.4e-34 118.8 0.5 4e-34 118.1 0.5 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EAX89510.1 - 2.4e-09 36.8 0.4 8.3e-09 35.0 0.4 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 EAX89510.1 - 7.1e-06 25.5 0.0 2.7e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Gly_rich PF12810.7 EAX89511.1 - 1.4e-35 123.4 31.7 1.7e-35 123.1 31.7 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF5365 PF17326.2 EAX89512.1 - 0.029 14.8 0.3 0.061 13.7 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX89512.1 - 0.031 14.6 0.3 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF3781 PF12636.7 EAX89513.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX89514.1 - 7e-74 247.4 4.5 8.3e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX89514.1 - 0.15 10.5 1.0 0.2 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF2897 PF11446.8 EAX89515.1 - 0.14 12.1 2.7 0.19 11.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX89516.1 - 5.4e-63 211.2 5.8 6e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4795 PF16043.5 EAX89517.1 - 0.45 10.1 6.6 2.5 7.7 6.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) LRR_5 PF13306.6 EAX89518.1 - 2.5e-14 53.3 5.2 9.4e-09 35.3 0.5 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) TMEM154 PF15102.6 EAX89518.1 - 0.029 14.3 5.9 0.055 13.4 5.4 1.6 1 1 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 EAX89518.1 - 0.065 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Adeno_E4_34 PF04528.13 EAX89518.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region LRR_5 PF13306.6 EAX89519.1 - 3e-25 88.6 26.8 1.6e-15 57.2 6.9 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89519.1 - 9.4e-05 22.1 0.1 0.38 10.5 0.0 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EAX89519.1 - 0.0067 16.8 0.3 7.7 7.1 0.0 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) bPH_3 PF14470.6 EAX89519.1 - 0.01 16.2 7.1 0.012 16.0 3.4 2.2 1 1 1 2 2 2 0 Bacterial PH domain PI-PLC-X PF00388.19 EAX89519.1 - 0.22 11.1 2.2 0.9 9.1 0.4 2.5 2 1 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain LRR_5 PF13306.6 EAX89520.1 - 5.4e-12 45.8 8.5 5.4e-12 45.8 8.5 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX89521.1 - 1.3e-12 47.8 7.9 2.4e-12 46.9 7.9 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Orf78 PF06024.12 EAX89521.1 - 0.2 11.9 3.4 0.38 11.1 3.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Tub PF01167.18 EAX89522.1 - 1.1e-11 44.9 5.5 1.9e-09 37.7 1.4 2.1 1 1 0 2 2 2 2 Tub family NDT80_PhoG PF05224.12 EAX89522.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family ADK PF00406.22 EAX89523.1 - 1.2e-10 41.7 0.0 2.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAX89523.1 - 2.6e-08 34.4 0.0 1.9e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EAX89523.1 - 8.4e-06 26.2 0.6 8.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Dpy-30 PF05186.13 EAX89523.1 - 0.00072 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Dpy-30 motif AAA_18 PF13238.6 EAX89523.1 - 0.0024 18.4 0.1 0.025 15.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain Epimerase PF01370.21 EAX89523.1 - 0.029 13.8 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA_22 PF13401.6 EAX89523.1 - 0.098 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAX89523.1 - 0.12 12.6 0.2 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain GDP_Man_Dehyd PF16363.5 EAX89523.1 - 0.17 11.2 1.7 1.9 7.8 0.0 2.6 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 EAX89525.1 - 6e-66 222.5 0.0 7.4e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89525.1 - 3.3e-34 118.3 0.0 4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89525.1 - 2.2e-05 23.9 0.0 5.6e-05 22.6 0.0 1.7 2 1 1 3 3 3 1 Kinase-like PH PF00169.29 EAX89525.1 - 0.01 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 PH domain RIO1 PF01163.22 EAX89525.1 - 0.035 13.7 0.0 2.1 7.9 0.0 2.1 1 1 1 2 2 2 0 RIO1 family FAS_N PF17828.1 EAX89527.1 - 0.02 14.9 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX89528.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX89529.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX89529.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX89530.1 - 3.3e-155 514.6 12.9 4.1e-155 514.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89530.1 - 4.8 7.7 7.5 1.9 9.0 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX89531.1 - 1.7e-09 37.6 37.6 4.8e-08 32.9 4.8 5.3 6 0 0 6 6 6 3 Phage tail repeat like Amidase02_C PF12123.8 EAX89533.1 - 0.01 15.5 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX89534.1 - 6.4e-71 237.8 3.5 8.4e-71 237.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4456 PF14644.6 EAX89535.1 - 4.3e-27 95.2 1.3 4.3e-27 95.2 1.3 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) Transposase_1 PF01359.18 EAX89536.1 - 1.4e-10 40.9 0.1 1.4e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 Transposase (partial DDE domain) PWI PF01480.17 EAX89537.1 - 0.063 13.6 0.6 0.18 12.2 0.1 2.0 3 0 0 3 3 3 0 PWI domain MULE PF10551.9 EAX89538.1 - 1.7e-10 41.1 2.2 6e-10 39.4 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX89538.1 - 0.0022 18.0 1.1 0.0074 16.4 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX89538.1 - 0.0056 15.6 0.2 0.0098 14.8 0.2 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Beach PF02138.18 EAX89539.1 - 1.1e-49 169.2 3.6 1.4e-48 165.7 3.6 2.7 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX89539.1 - 1.5e-10 40.8 2.9 2.1e-10 40.4 0.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) ANAPC4_WD40 PF12894.7 EAX89539.1 - 0.03 14.6 0.1 0.19 12.1 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Colipase-like PF15083.6 EAX89539.1 - 0.092 12.9 0.2 0.28 11.3 0.2 1.8 1 0 0 1 1 1 0 Colipase-like PSP PF04046.16 EAX89540.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89541.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX89543.1 - 1.5e-85 286.5 7.3 1.7e-85 286.3 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX89543.1 - 0.021 14.3 0.1 0.023 14.2 0.1 1.1 1 0 0 1 1 1 0 Z1 domain DDE_Tnp_4 PF13359.6 EAX89544.1 - 3.6e-20 72.2 0.0 1e-19 70.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX89544.1 - 1.7e-14 54.0 0.7 8.3e-14 51.7 0.7 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX89544.1 - 0.0013 18.4 4.3 0.006 16.2 1.2 2.7 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX89544.1 - 0.0059 16.1 0.5 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Thioredoxin PF00085.20 EAX89545.1 - 3.9e-13 49.3 0.0 4.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX89545.1 - 0.0036 17.6 0.0 2.3 8.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EAX89545.1 - 0.0048 16.3 0.0 0.0054 16.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 EAX89545.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.6 1 1 1 2 2 2 0 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 EAX89545.1 - 0.079 13.4 0.0 1.9 9.0 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.32 EAX89546.1 - 2.6e-11 43.9 10.0 0.00026 21.7 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 EAX89546.1 - 0.00013 21.4 2.9 0.0098 15.3 0.2 3.2 1 1 1 3 3 3 1 WD40-like domain HALZ PF02183.18 EAX89546.1 - 0.00061 20.0 0.1 0.0012 19.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper ANAPC4_WD40 PF12894.7 EAX89546.1 - 0.002 18.4 0.1 4.2 7.7 0.0 4.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DivIVA PF05103.13 EAX89546.1 - 0.088 12.9 0.5 0.17 12.0 0.2 1.5 1 1 0 1 1 1 0 DivIVA protein YabA PF06156.13 EAX89546.1 - 0.18 12.4 0.1 0.35 11.5 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Mto2_bdg PF12808.7 EAX89546.1 - 4.6 7.6 9.0 2.1 8.7 0.4 2.3 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ank_4 PF13637.6 EAX89547.1 - 5.3e-146 473.3 51.9 7.7e-12 45.5 0.1 20.9 3 1 18 21 21 21 19 Ankyrin repeats (many copies) Ank PF00023.30 EAX89547.1 - 9.8e-138 443.2 47.4 3.3e-07 30.4 0.0 20.4 20 0 0 20 20 20 20 Ankyrin repeat Ank_2 PF12796.7 EAX89547.1 - 1.2e-133 435.9 80.5 6.7e-15 55.4 4.0 12.6 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89547.1 - 1.5e-126 410.8 64.3 8.2e-12 45.1 0.5 12.8 3 2 11 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89547.1 - 1e-120 378.8 37.2 2.3e-05 24.4 0.0 21.2 21 0 0 21 21 21 19 Ankyrin repeat DUF3447 PF11929.8 EAX89547.1 - 1e-37 127.9 4.9 1e-37 127.9 4.9 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX89547.1 - 2.2e-11 43.9 5.1 19 5.6 0.0 13.1 3 3 13 16 16 16 0 N terminal of Calcineurin-like phosphoesterase Endonuc-dimeris PF09124.10 EAX89547.1 - 0.00041 20.4 11.0 21 5.4 0.0 8.6 8 2 1 9 9 9 0 T4 recombination endonuclease VII, dimerisation S4 PF01479.25 EAX89547.1 - 0.0043 16.7 0.6 31 4.4 0.0 7.4 16 0 0 16 16 16 0 S4 domain HeH PF12949.7 EAX89547.1 - 0.051 13.3 14.8 42 4.0 0.0 5.7 5 0 0 5 5 5 0 HeH/LEM domain DUF2113 PF09886.9 EAX89547.1 - 0.15 11.4 11.1 14 5.0 0.0 5.5 3 2 5 8 8 8 0 Uncharacterized protein conserved in archaea (DUF2113) DUF3718 PF12514.8 EAX89547.1 - 0.26 11.4 42.1 24 5.2 0.1 13.6 12 3 5 17 17 17 0 Protein of unknown function (DUF3718) DUF348 PF03990.14 EAX89547.1 - 0.3 10.9 1.5 4e+02 0.9 0.0 5.2 5 0 0 5 5 5 0 G5-linked-Ubiquitin-like domain P2_Phage_GpR PF06891.11 EAX89547.1 - 3.8 7.6 20.1 1.4e+02 2.5 0.1 9.4 5 2 8 13 13 13 0 P2 phage tail completion protein R (GpR) Exo_endo_phos PF03372.23 EAX89548.1 - 3.1e-05 23.6 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 EAX89548.1 - 0.0001 22.1 0.0 0.0006 19.7 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain DUF728 PF05304.12 EAX89548.1 - 0.036 13.9 0.4 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Motile_Sperm PF00635.26 EAX89548.1 - 0.039 13.8 0.3 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DUF1573 PF07610.11 EAX89548.1 - 0.047 13.7 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Ank_2 PF12796.7 EAX89549.1 - 2.9e-143 466.8 119.1 2.2e-15 57.0 3.1 11.0 3 2 12 15 15 15 12 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89549.1 - 7.3e-118 380.4 55.9 7.7e-09 35.6 0.1 15.6 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.6 EAX89549.1 - 3.3e-110 359.1 54.4 4.6e-13 49.4 0.1 16.3 2 1 14 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89549.1 - 3.6e-91 288.1 32.9 6.4e-06 26.1 0.0 16.3 17 0 0 17 17 16 14 Ankyrin repeat Ank_5 PF13857.6 EAX89549.1 - 4.5e-68 224.4 44.4 2.2e-10 40.6 0.3 12.3 6 3 7 14 14 14 11 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89549.1 - 2.3e-17 62.7 6.2 2.3e-17 62.7 6.2 3.7 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EAX89549.1 - 0.00069 19.8 23.4 17 5.8 0.8 9.3 2 1 8 11 11 10 0 Ribosomal protein S6 Exotox-A_target PF09102.10 EAX89549.1 - 0.046 13.7 2.7 8 6.5 0.0 4.8 2 1 6 8 8 8 0 Exotoxin A, targeting P2_Phage_GpR PF06891.11 EAX89549.1 - 0.61 10.2 3.1 1.3e+02 2.6 0.0 4.5 2 2 2 4 4 4 0 P2 phage tail completion protein R (GpR) DUF3130 PF11328.8 EAX89549.1 - 3.9 7.8 20.0 26 5.2 0.1 7.0 2 2 5 8 8 8 0 Protein of unknown function (DUF3130 PrmC_N PF17827.1 EAX89549.1 - 7.6 7.2 11.1 1.2e+02 3.4 0.0 7.1 4 2 3 7 7 7 0 PrmC N-terminal domain DUF3718 PF12514.8 EAX89549.1 - 8.3 6.6 39.7 4.6 7.5 0.6 10.6 5 3 7 12 12 12 0 Protein of unknown function (DUF3718) QRPTase_C PF01729.19 EAX89549.1 - 9.1 6.0 12.9 13 5.5 0.2 4.9 2 1 2 5 5 5 0 Quinolinate phosphoribosyl transferase, C-terminal domain Thioredoxin PF00085.20 EAX89550.1 - 1.2e-23 83.1 0.1 1.4e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX89550.1 - 0.00017 22.0 0.3 0.0039 17.6 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX89550.1 - 0.00042 20.6 0.0 0.0035 17.6 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EAX89550.1 - 0.0087 15.4 0.0 0.009 15.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EAX89550.1 - 0.0089 15.9 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EAX89550.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 EAX89550.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.6 EAX89550.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin IBD PF10416.9 EAX89551.1 - 3.8e-44 149.8 0.3 5.8e-44 149.2 0.3 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD eIF-3c_N PF05470.12 EAX89551.1 - 0.14 10.4 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spo12 PF05032.12 EAX89552.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF3839 PF12943.7 EAX89553.1 - 3.6e-135 449.0 10.4 4.3e-135 448.8 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX89553.1 - 0.1 13.0 0.6 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX89553.1 - 0.11 13.0 3.2 0.14 12.6 0.8 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX89553.1 - 0.79 10.2 7.1 5.4 7.5 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX89555.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89556.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ribosomal_S27 PF01599.19 EAX89557.1 - 3.3e-17 62.4 5.3 3.3e-17 62.4 5.3 2.2 2 0 0 2 2 2 1 Ribosomal protein S27a Cript PF10235.9 EAX89557.1 - 0.27 11.8 7.3 0.49 11.0 7.3 1.4 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Auto_anti-p27 PF06677.12 EAX89557.1 - 0.51 10.5 4.6 0.82 9.9 4.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRN7 PF11781.8 EAX89557.1 - 1.7 8.4 9.7 0.76 9.5 6.8 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RabGAP-TBC PF00566.18 EAX89559.1 - 4.9e-24 85.2 0.1 7.6e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Colicin_K PF17500.2 EAX89559.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.2 3 0 0 3 3 3 0 Colicin-K MerR-DNA-bind PF09278.11 EAX89560.1 - 0.046 14.3 1.1 25 5.5 0.0 3.1 2 1 1 3 3 3 0 MerR, DNA binding ZapB PF06005.12 EAX89560.1 - 0.28 11.6 6.6 1.2 9.6 1.6 2.7 2 0 0 2 2 2 0 Cell division protein ZapB DUF3810 PF12725.7 EAX89560.1 - 0.4 10.0 7.3 0.084 12.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Baculo_PEP_C PF04513.12 EAX89560.1 - 0.42 10.7 7.9 0.57 10.2 2.7 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 EAX89560.1 - 0.82 9.8 5.6 1.3 9.2 1.8 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF5595 PF18077.1 EAX89560.1 - 1.2 9.2 6.4 0.48 10.5 1.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Uso1_p115_C PF04871.13 EAX89560.1 - 7.1 7.0 9.5 30 5.0 4.2 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KIP1 PF07765.12 EAX89560.1 - 7.6 6.7 16.0 0.43 10.7 3.7 3.0 2 1 1 3 3 3 0 KIP1-like protein Ank_2 PF12796.7 EAX89561.1 - 1.6e-13 51.1 0.1 1.2e-12 48.3 0.0 2.3 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89561.1 - 3.7e-10 39.9 0.0 4.5e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89561.1 - 1.3e-08 35.2 0.1 0.00028 21.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89561.1 - 3.6e-08 33.0 0.1 0.0037 17.6 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAX89561.1 - 4e-07 30.2 0.0 0.00011 22.4 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat GOLGA2L5 PF15070.6 EAX89561.1 - 0.0066 15.2 2.2 0.008 14.9 2.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 HemX PF04375.14 EAX89561.1 - 0.0069 15.7 2.6 0.0095 15.3 2.6 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2205 PF10224.9 EAX89561.1 - 0.0073 16.3 2.8 0.0073 16.3 2.8 1.8 2 0 0 2 2 2 1 Short coiled-coil protein ZapB PF06005.12 EAX89561.1 - 0.013 15.9 8.0 0.03 14.7 8.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 EAX89561.1 - 0.015 15.5 0.7 0.015 15.5 0.7 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 EAX89561.1 - 0.022 14.8 4.9 0.038 14.0 4.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.15 EAX89561.1 - 0.036 14.2 9.0 0.026 14.7 6.7 1.9 2 1 0 2 2 2 0 RasGAP C-terminus DivIC PF04977.15 EAX89561.1 - 0.054 13.3 6.6 0.078 12.8 5.5 1.8 2 0 0 2 2 2 0 Septum formation initiator TLE_N PF03920.15 EAX89561.1 - 0.061 13.4 1.4 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain KELK PF15796.5 EAX89561.1 - 0.095 13.2 3.2 0.23 11.9 3.2 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc24 PF08286.11 EAX89561.1 - 0.11 12.8 6.0 0.2 11.9 6.0 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 EAX89561.1 - 0.24 12.0 6.4 0.38 11.4 4.6 2.4 2 1 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EAX89561.1 - 0.42 11.1 8.1 0.53 10.8 7.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 EAX89561.1 - 0.61 10.5 7.7 0.75 10.2 7.2 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mre11_DNA_bind PF04152.14 EAX89561.1 - 0.69 10.2 4.3 0.41 10.9 0.5 2.0 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain CALCOCO1 PF07888.11 EAX89561.1 - 1.4 7.7 7.3 1.8 7.4 7.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 EAX89561.1 - 1.6 9.2 6.7 0.39 11.1 2.3 2.2 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) TMP PF05017.14 EAX89562.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4107 PF13389.6 EAX89565.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pyridox_ox_2 PF12900.7 EAX89566.1 - 2.1e-19 69.9 0.0 2.5e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 EAX89566.1 - 4.5e-06 26.5 0.0 1.2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Putative FMN-binding domain Putative_PNPOx PF01243.20 EAX89566.1 - 0.0002 21.5 0.0 0.00061 19.9 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Nitroreductase PF00881.24 EAX89567.1 - 6.5e-27 94.7 0.0 7.3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX89567.1 - 0.02 14.5 0.2 4 6.9 0.0 2.7 1 1 2 3 3 3 0 Putative TM nitroreductase CompInhib_SCIN PF11546.8 EAX89568.1 - 0.041 13.9 0.1 0.31 11.1 0.1 2.5 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN zf-RING_2 PF13639.6 EAX89570.1 - 2.7e-05 24.4 10.0 7.9e-05 22.9 10.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX89570.1 - 0.00044 20.1 6.7 0.00044 20.1 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX89570.1 - 0.00045 20.2 4.1 0.00048 20.1 2.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAX89570.1 - 0.0028 17.9 5.4 0.0083 16.4 5.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAX89570.1 - 0.0064 16.4 9.2 0.016 15.2 9.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EAX89570.1 - 0.0069 16.1 7.1 0.0069 16.1 7.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger MTCP1 PF08991.10 EAX89570.1 - 0.02 15.1 0.6 0.045 14.0 0.6 1.6 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Vps39_2 PF10367.9 EAX89570.1 - 0.073 13.5 3.9 0.05 14.1 1.5 2.1 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 EAX89570.1 - 0.12 12.2 14.5 0.047 13.5 10.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAX89570.1 - 0.14 11.8 3.8 0.3 10.7 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EAX89570.1 - 0.14 12.2 9.7 0.057 13.5 4.3 2.4 2 0 0 2 2 2 0 Zinc-finger Zf_RING PF16744.5 EAX89570.1 - 0.29 11.3 4.2 0.74 10.0 4.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger UPF0547 PF10571.9 EAX89570.1 - 2.8 8.1 5.1 10 6.3 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.14 EAX89570.1 - 9.4 6.3 8.8 3.4 7.7 0.3 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Ank_2 PF12796.7 EAX89571.1 - 1.9e-96 316.8 43.5 3.3e-19 69.2 0.3 7.6 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89571.1 - 8.9e-74 243.0 22.3 6.1e-15 55.4 0.0 11.6 3 1 10 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX89571.1 - 1.8e-70 230.5 19.4 1.9e-09 37.5 0.0 12.7 12 1 1 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 EAX89571.1 - 1.4e-57 190.9 19.3 6.3e-11 42.3 0.1 9.6 7 1 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89571.1 - 3.8e-57 183.5 21.6 7e-07 29.1 0.0 13.5 14 1 1 15 15 15 10 Ankyrin repeat DUF3447 PF11929.8 EAX89571.1 - 1.7e-27 95.2 4.5 1.7e-27 95.2 4.5 6.5 4 2 4 8 8 8 2 Domain of unknown function (DUF3447) TNF PF00229.18 EAX89572.1 - 0.013 15.4 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family HECT PF00632.25 EAX89575.1 - 1.3e-20 74.1 0.4 9.5e-19 68.0 0.5 2.1 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Glyco_hydro_77 PF02446.17 EAX89578.1 - 3.3e-146 487.8 7.2 4.5e-146 487.4 7.2 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAX89578.1 - 1.8e-41 139.9 0.2 5.1e-20 71.2 0.0 2.7 2 0 0 2 2 2 2 Starch binding domain Tox-ODYAM1 PF15642.6 EAX89578.1 - 0.094 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus CBM_48 PF02922.18 EAX89578.1 - 0.43 11.0 2.8 6.4 7.2 0.2 3.1 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AntA PF08346.12 EAX89578.1 - 4.2 8.0 7.4 3.3 8.3 0.2 3.5 3 0 0 3 3 3 0 AntA/AntB antirepressor EF-hand_1 PF00036.32 EAX89579.1 - 5.1e-27 91.4 9.5 8.3e-07 28.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX89579.1 - 5.7e-27 94.0 5.0 7.8e-13 48.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX89579.1 - 4e-26 88.7 3.5 1.3e-06 27.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX89579.1 - 9.2e-19 67.0 6.1 4.2e-07 29.7 1.1 4.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EAX89579.1 - 3.1e-17 61.2 4.4 3.1e-06 26.4 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX89579.1 - 1e-13 51.4 0.5 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX89579.1 - 1.5e-07 31.7 2.2 0.0022 18.3 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EAX89579.1 - 3.4e-07 30.0 7.3 0.049 13.5 1.5 3.7 2 1 2 4 4 4 3 EF hand EF-hand_4 PF12763.7 EAX89579.1 - 2.1e-05 24.4 4.8 0.0068 16.3 0.1 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 EAX89579.1 - 2.1e-05 24.7 4.1 0.0061 16.7 0.4 2.3 1 1 1 2 2 2 2 p25-alpha EF-hand_14 PF17959.1 EAX89579.1 - 0.0006 20.1 4.0 0.88 10.0 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 EAX89579.1 - 0.00081 19.4 3.8 4.5 7.2 0.1 3.8 1 1 1 3 3 3 2 Caleosin related protein DUF2666 PF10869.8 EAX89579.1 - 0.0032 17.7 3.0 0.034 14.4 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2666) EF-hand_11 PF08976.11 EAX89579.1 - 0.0038 18.1 1.3 0.71 10.8 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain DUF1160 PF06648.11 EAX89579.1 - 0.0095 15.9 1.0 0.12 12.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1160) PMBR PF09373.10 EAX89579.1 - 0.014 15.5 1.2 30 5.0 0.0 4.2 4 2 2 6 6 6 0 Pseudomurein-binding repeat SMC_Nse1 PF07574.13 EAX89579.1 - 0.018 15.0 1.1 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Vps23_core PF09454.10 EAX89579.1 - 0.025 14.5 0.0 1.5 8.8 0.0 2.7 2 1 0 2 2 2 0 Vps23 core domain Toprim PF01751.22 EAX89579.1 - 0.032 14.4 0.3 0.056 13.7 0.3 1.5 1 1 0 1 1 1 0 Toprim domain Polo_box_3 PF18544.1 EAX89579.1 - 0.056 14.1 1.1 1.6 9.4 0.1 2.3 1 1 1 2 2 2 0 Polo box domain TFIIE_beta PF02186.15 EAX89579.1 - 0.056 13.7 1.6 2 8.7 0.1 3.2 1 1 3 4 4 4 0 TFIIE beta subunit core domain RST PF12174.8 EAX89579.1 - 0.065 13.2 0.7 1.8 8.5 0.0 2.7 2 2 2 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain Dockerin_1 PF00404.18 EAX89579.1 - 0.068 13.4 0.1 3 8.1 0.1 3.0 2 1 1 3 3 3 0 Dockerin type I domain Clr5 PF14420.6 EAX89579.1 - 0.1 12.8 0.2 0.29 11.4 0.1 1.8 2 0 0 2 2 1 0 Clr5 domain Prefoldin_3 PF13758.6 EAX89579.1 - 0.11 12.6 1.5 0.36 10.9 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit MMPL PF03176.15 EAX89579.1 - 0.22 10.4 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 MMPL family C2 PF00168.30 EAX89580.1 - 0.013 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 C2 domain LRR_5 PF13306.6 EAX89581.1 - 1.2e-101 335.6 66.2 4.9e-22 78.3 4.0 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89581.1 - 1.2e-13 50.6 11.9 0.63 9.8 0.0 10.1 9 2 4 13 13 13 7 Leucine rich repeat LRR_4 PF12799.7 EAX89581.1 - 3.3e-05 24.2 9.9 0.73 10.3 0.0 8.0 9 0 0 9 9 9 1 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 EAX89581.1 - 0.045 14.0 0.8 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Gly-zipper_Omp PF13488.6 EAX89582.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX89582.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX89582.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif C2 PF00168.30 EAX89583.1 - 1.1e-58 195.9 6.1 3.6e-23 81.8 0.0 3.4 3 1 0 3 3 3 3 C2 domain DUF755 PF05501.11 EAX89583.1 - 0.018 15.3 9.3 0.018 15.3 9.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Roughex PF06020.11 EAX89583.1 - 0.064 12.4 1.0 0.1 11.7 1.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DOCK-C2 PF14429.6 EAX89583.1 - 1.7 8.4 9.3 5.9 6.6 0.1 3.3 3 1 1 4 4 4 0 C2 domain in Dock180 and Zizimin proteins DUF4820 PF16091.5 EAX89583.1 - 5.1 6.4 9.9 4.1 6.7 2.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) C2 PF00168.30 EAX89584.1 - 1e-138 453.0 19.5 3.4e-22 78.7 0.1 6.8 7 0 0 7 7 7 6 C2 domain DOCK-C2 PF14429.6 EAX89584.1 - 7.6e-16 58.5 6.3 0.00037 20.4 0.0 7.0 7 1 0 7 7 7 3 C2 domain in Dock180 and Zizimin proteins B9-C2 PF07162.11 EAX89584.1 - 7e-09 36.1 0.0 1.5 9.0 0.0 6.6 6 1 1 7 7 7 2 Ciliary basal body-associated, B9 protein TonB_2 PF13103.6 EAX89584.1 - 0.00024 21.3 0.1 7.3 6.9 0.0 4.6 4 0 0 4 4 4 1 TonB C terminal CEP76-C2 PF15627.6 EAX89584.1 - 0.00038 20.0 0.0 11 5.6 0.0 5.2 6 0 0 6 6 6 1 CEP76 C2 domain DUF5622 PF18533.1 EAX89584.1 - 0.01 16.0 2.5 35 4.7 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5622) ALS_ss_C PF10369.9 EAX89584.1 - 0.021 15.0 0.2 31 4.9 0.0 3.5 3 0 0 3 3 3 0 Small subunit of acetolactate synthase Big_1 PF02369.16 EAX89584.1 - 0.53 10.3 3.4 29 4.8 0.1 3.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Dehydrin PF00257.19 EAX89584.1 - 2.3 8.8 14.0 7.4 7.1 0.4 3.4 3 0 0 3 3 3 0 Dehydrin PMT_4TMC PF16192.5 EAX89585.1 - 8.5e-21 74.5 22.9 2e-19 70.0 22.9 2.0 1 1 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 EAX89586.1 - 2.5e-37 128.8 10.6 3.1e-37 128.5 10.6 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TLD PF07534.16 EAX89588.1 - 9.6e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 TLD IPI_T4 PF11634.8 EAX89588.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 Ank PF00023.30 EAX89589.1 - 1.4e-21 75.9 0.3 5.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX89589.1 - 1.7e-19 69.6 0.4 1.6e-11 44.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89589.1 - 1.7e-18 67.0 0.4 1.8e-17 63.7 0.4 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89589.1 - 3e-18 65.9 0.4 9.4e-15 54.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89589.1 - 2.9e-17 61.0 0.3 6.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat CEP44 PF15007.6 EAX89589.1 - 0.0006 20.0 0.0 0.7 10.1 0.0 2.0 1 1 1 2 2 2 2 Centrosomal spindle body, CEP44 ThiS-like PF14453.6 EAX89589.1 - 0.0026 17.8 0.3 0.9 9.6 0.0 2.1 1 1 1 2 2 2 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX89589.1 - 0.013 15.8 0.0 0.74 10.1 0.0 2.2 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Arylesterase PF01731.20 EAX89589.1 - 0.061 13.5 0.2 9.3 6.5 0.0 2.0 1 1 1 2 2 2 0 Arylesterase Fcf2 PF08698.11 EAX89590.1 - 3e-25 88.4 0.1 6.1e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing HisG PF01634.18 EAX89591.1 - 0.08 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 ATP phosphoribosyltransferase T2SSM PF04612.12 EAX89592.1 - 0.24 11.5 0.1 0.34 11.0 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2789 PF10982.8 EAX89593.1 - 0.071 13.3 1.2 0.53 10.5 1.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2789) APG6_N PF17675.1 EAX89593.1 - 0.29 11.6 14.8 0.052 14.1 11.4 1.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 EAX89593.1 - 3.3 8.1 19.7 0.62 10.5 15.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RP-C_C PF11800.8 EAX89593.1 - 5.6 7.0 14.5 0.11 12.5 6.4 1.9 1 1 1 2 2 2 0 Replication protein C C-terminal region DUF4407 PF14362.6 EAX89593.1 - 7.1 5.9 7.7 9.7 5.4 7.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L44 PF00935.19 EAX89594.1 - 7.1e-25 87.3 9.9 7.1e-25 87.3 9.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Rpr2 PF04032.16 EAX89594.1 - 0.11 12.8 6.1 0.32 11.3 6.1 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 EAX89594.1 - 0.12 12.9 13.7 2 9.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 EAX89594.1 - 1.1 9.6 9.1 0.23 11.7 1.3 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.11 EAX89594.1 - 1.1 9.5 10.7 0.1 12.8 1.6 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.13 EAX89594.1 - 2.3 8.3 15.9 3.6 7.7 1.6 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like IBP39 PF11422.8 EAX89595.1 - 1.6e-53 181.1 1.9 2.6e-53 180.5 1.9 1.3 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 EAX89595.1 - 1.9e-19 69.9 2.3 3.5e-19 69.1 2.3 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 EAX89597.1 - 9.8e-57 192.3 0.0 1.2e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89597.1 - 1.9e-20 73.2 0.0 1.4e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX89597.1 - 0.00035 20.6 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX89597.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAX89597.1 - 0.005 16.4 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAX89597.1 - 0.011 15.3 0.1 3.8 7.1 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX89597.1 - 0.024 13.4 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX89597.1 - 0.027 13.8 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 EAX89599.1 - 1.5e-49 167.7 0.0 1.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89599.1 - 7.1e-32 110.1 0.0 1.1e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89599.1 - 1.4e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX89599.1 - 7.8e-07 29.1 0.1 0.0022 17.9 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX89599.1 - 8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX89599.1 - 1.7e-05 24.3 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX89599.1 - 0.00031 20.2 0.0 0.00056 19.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX89599.1 - 0.008 15.7 0.1 0.04 13.5 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EAX89599.1 - 0.0085 15.8 0.2 0.18 11.5 0.2 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX89599.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_33 PF13671.6 EAX89599.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX89599.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RcpB PF16971.5 EAX89599.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Rough colony protein B, tight adherence - tad - subunit AAA_24 PF13479.6 EAX89599.1 - 0.04 13.6 0.1 0.091 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89599.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EAX89599.1 - 0.08 12.1 0.2 0.5 9.5 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 EAX89599.1 - 0.096 13.0 0.2 1.5 9.1 0.1 2.5 1 1 2 3 3 3 0 AAA domain Ydr279_N PF17745.1 EAX89600.1 - 1.8e-06 28.1 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 EAX89600.1 - 0.00028 21.1 0.6 0.0042 17.3 0.6 2.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Med1 PF10744.9 EAX89601.1 - 0.025 13.6 0.2 1.2 8.1 0.0 2.6 2 2 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 NRIP1_repr_3 PF15689.5 EAX89601.1 - 0.11 12.9 0.1 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 LSM PF01423.22 EAX89602.1 - 1.7e-15 56.4 0.1 2e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SAM_adeno_trans PF01887.16 EAX89602.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase SM-ATX PF14438.6 EAX89602.1 - 0.046 13.9 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EAX89602.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain WD40 PF00400.32 EAX89603.1 - 2.2e-11 44.1 11.4 0.025 15.5 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX89603.1 - 0.00071 19.8 0.1 2.7 8.4 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NAC PF01849.18 EAX89604.1 - 1e-13 51.0 0.3 3.4e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 NAC domain Nrf1_DNA-bind PF10491.9 EAX89604.1 - 0.016 14.9 2.1 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 HU-CCDC81_bac_2 PF18175.1 EAX89604.1 - 0.17 11.8 0.2 16 5.5 0.0 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Pkinase PF00069.25 EAX89605.1 - 3.2e-60 203.7 0.0 4.2e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89605.1 - 8.1e-40 136.7 0.0 9.8e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89605.1 - 1.1e-08 34.7 0.0 2e-06 27.4 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAX89605.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX89605.1 - 0.0055 15.7 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX89605.1 - 0.035 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EAX89605.1 - 0.07 12.7 0.0 0.48 10.0 0.1 2.0 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EAX89605.1 - 0.081 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_5 PF13306.6 EAX89606.1 - 2.9e-92 305.3 31.6 4.4e-22 78.4 0.9 5.1 2 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89606.1 - 2.6e-10 39.9 0.0 0.47 10.3 0.0 9.0 6 3 6 12 12 12 4 Leucine rich repeat Pkinase PF00069.25 EAX89607.1 - 5.7e-50 170.1 0.0 7.2e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89607.1 - 4.3e-32 111.4 0.0 5.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89607.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EAX89607.1 - 0.043 12.9 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 EAX89607.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPL PF17800.1 EAX89608.1 - 5.3e-11 43.0 0.0 7.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain Fringe PF02434.16 EAX89609.1 - 0.063 12.7 0.1 0.069 12.6 0.1 1.1 1 0 0 1 1 1 0 Fringe-like Titin_Ig-rpts PF06582.12 EAX89610.1 - 0.19 11.7 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Titin repeat UCH PF00443.29 EAX89611.1 - 6.4e-43 147.1 5.0 6.4e-43 147.1 5.0 3.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX89611.1 - 9.6e-15 55.0 11.5 2.5e-09 37.2 0.4 3.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase eIF3_p135 PF12807.7 EAX89611.1 - 0.053 13.5 3.1 0.088 12.8 1.5 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 EF-hand_2 PF09068.11 EAX89611.1 - 0.093 12.9 2.9 0.2 11.8 0.3 3.2 3 0 0 3 3 3 0 EF hand TMEM154 PF15102.6 EAX89612.1 - 0.00013 21.9 3.1 0.00021 21.2 3.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EAX89612.1 - 0.00023 21.5 0.8 0.00023 21.5 0.8 1.9 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Rax2 PF12768.7 EAX89612.1 - 0.00087 18.8 0.3 0.0015 18.0 0.3 1.3 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Orf78 PF06024.12 EAX89612.1 - 0.0032 17.7 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 EAX89612.1 - 0.012 15.5 0.5 0.015 15.2 0.5 1.1 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 EAX89612.1 - 0.013 15.6 0.8 0.016 15.3 0.8 1.2 1 0 0 1 1 1 0 Podoplanin DUF4711 PF15829.5 EAX89612.1 - 0.016 15.1 0.6 0.028 14.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Mid2 PF04478.12 EAX89612.1 - 0.022 14.6 3.0 0.029 14.2 2.2 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5383 PF17355.2 EAX89612.1 - 0.031 14.6 0.5 0.067 13.6 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) ABC2_membrane_3 PF12698.7 EAX89612.1 - 0.043 12.9 1.3 0.056 12.5 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4690 PF15756.5 EAX89612.1 - 0.057 14.0 0.9 0.12 13.0 0.9 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4366 PF14283.6 EAX89612.1 - 0.074 13.1 0.7 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) LRRC37AB_C PF14914.6 EAX89612.1 - 0.087 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain ORC6 PF05460.13 EAX89612.1 - 0.35 10.1 5.9 0.48 9.7 5.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ETRAMP PF09716.10 EAX89612.1 - 0.81 9.8 3.7 1.1 9.4 3.7 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FeoB_associated PF12669.7 EAX89612.1 - 1 9.8 5.1 1.7 9.1 5.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 EAX89612.1 - 1 10.3 4.3 2.8 8.9 4.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX89612.1 - 1.3 9.0 3.8 3.6 7.6 3.8 1.7 1 0 0 1 1 1 0 Syndecan domain Sigma_reg_N PF13800.6 EAX89612.1 - 10 6.5 9.8 1.1 9.5 2.8 2.5 2 1 0 2 2 2 0 Sigma factor regulator N-terminal Gln-synt_N PF03951.19 EAX89613.1 - 0.024 14.4 0.2 0.18 11.5 0.0 2.6 2 1 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain SH2 PF00017.24 EAX89613.1 - 0.11 12.6 0.6 0.51 10.5 0.1 2.3 2 0 0 2 2 2 0 SH2 domain DUF3839 PF12943.7 EAX89614.1 - 4.3e-52 177.0 2.8 4.9e-52 176.8 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX89614.1 - 0.062 12.8 0.1 0.064 12.7 0.1 1.0 1 0 0 1 1 1 0 Z1 domain KilA-N PF04383.13 EAX89615.1 - 6.7e-27 93.6 1.3 9.9e-27 93.0 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX89615.1 - 0.0025 18.0 0.0 0.0063 16.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX89616.1 - 2.5e-07 30.4 3.1 2.5e-07 30.4 3.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89616.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89616.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89616.1 - 0.00014 21.9 3.3 0.00033 20.7 3.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89616.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89616.1 - 0.0012 18.7 0.6 0.0021 17.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89616.1 - 0.0012 18.5 0.7 0.0066 16.1 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89616.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89616.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89616.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89616.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89616.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX89617.1 - 4.2e-61 205.1 7.4 4.7e-61 204.9 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX89618.1 - 2.6e-50 169.0 35.8 4.2e-18 65.7 5.9 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89618.1 - 1.1e-31 108.8 15.9 6.3e-10 39.4 0.1 6.9 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89618.1 - 2.2e-30 103.7 15.5 1.7e-06 28.2 0.2 6.1 5 1 1 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX89618.1 - 1.8e-29 98.5 14.5 9e-07 28.7 0.2 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX89618.1 - 2.3e-21 75.6 7.9 3.8e-10 39.8 0.9 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89618.1 - 2.9e-20 72.0 4.1 2.9e-20 72.0 4.1 4.8 2 2 1 4 4 4 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX89618.1 - 0.012 15.8 5.9 1 9.5 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3718) YcxB PF14317.6 EAX89618.1 - 0.014 15.1 0.2 10 5.9 0.0 4.1 4 0 0 4 4 4 0 YcxB-like protein MetallophosN PF16371.5 EAX89618.1 - 0.029 14.6 0.0 0.95 9.8 0.0 2.6 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Mic1 PF07035.12 EAX89618.1 - 0.15 11.8 1.5 2.2 8.0 0.1 3.0 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like SCVP PF17619.2 EAX89618.1 - 0.69 10.8 7.0 0.5 11.2 0.3 3.4 2 1 2 4 4 4 0 Secreted clade V proteins FAM176 PF14851.6 EAX89619.1 - 0.0058 16.3 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 FAM176 family Zip PF02535.22 EAX89619.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_LMP1 PF05297.11 EAX89619.1 - 0.12 11.5 0.4 0.19 10.9 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ly49 PF08391.10 EAX89619.1 - 0.3 11.4 3.0 0.35 11.2 0.2 2.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region MAP17 PF15807.5 EAX89619.1 - 3.6 7.8 6.8 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EF-hand_6 PF13405.6 EAX89620.1 - 4e-13 48.1 4.5 0.00011 21.8 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EAX89620.1 - 2.9e-11 43.7 1.1 1.7e-05 25.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX89620.1 - 4.8e-09 35.1 4.0 0.00078 18.8 0.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 EAX89620.1 - 0.0006 20.1 0.0 0.73 10.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain LXG PF04740.12 EAX89620.1 - 0.0012 18.6 0.2 0.0022 17.7 0.1 1.5 1 1 0 1 1 1 1 LXG domain of WXG superfamily EF-hand_5 PF13202.6 EAX89620.1 - 0.0013 18.1 1.7 0.061 12.8 0.3 2.6 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.6 EAX89620.1 - 0.016 15.7 0.1 0.92 10.0 0.0 2.2 1 1 1 2 2 2 0 Toprim-like EF-hand_8 PF13833.6 EAX89620.1 - 0.026 14.3 4.1 5.4 6.9 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain pair SAPS PF04499.15 EAX89621.1 - 0.03 13.1 0.1 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Aa_trans PF01490.18 EAX89622.1 - 1.2e-38 133.0 41.1 1.5e-38 132.6 41.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein T5orf172 PF10544.9 EAX89623.1 - 5.6e-05 23.6 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX89623.1 - 0.076 12.5 0.3 0.4 10.2 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX89624.1 - 6.9e-157 520.1 12.9 8.4e-157 519.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX89624.1 - 0.15 12.5 0.2 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX89624.1 - 0.17 11.8 1.5 0.41 10.5 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX89624.1 - 0.69 10.4 4.8 5.4 7.5 0.1 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Metallophos PF00149.28 EAX89625.1 - 1.3e-29 104.2 0.1 1.8e-29 103.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX89625.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF3447 PF11929.8 EAX89626.1 - 9.8e-25 86.3 6.5 9.8e-25 86.3 6.5 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89626.1 - 0.00036 21.1 0.1 0.62 10.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89626.1 - 0.0012 19.4 0.6 0.12 13.0 0.3 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) S1-P1_nuclease PF02265.16 EAX89627.1 - 1.5e-12 47.9 0.1 1.9e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF3447 PF11929.8 EAX89628.1 - 1.4e-37 127.5 6.2 1.4e-37 127.5 6.2 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89628.1 - 3.8e-27 94.7 9.6 2.2e-11 44.2 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89628.1 - 1.5e-26 92.4 2.7 3.8e-10 40.1 0.0 7.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89628.1 - 3.7e-23 81.3 6.0 7.1e-11 42.1 0.3 5.2 2 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89628.1 - 6.1e-23 78.4 3.6 0.00038 20.7 0.0 6.4 6 1 2 8 8 8 4 Ankyrin repeat Ank PF00023.30 EAX89628.1 - 9.5e-23 79.6 3.3 5.5e-05 23.4 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeat Methyltransf_14 PF08484.11 EAX89628.1 - 0.012 15.4 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain TB2_DP1_HVA22 PF03134.19 EAX89630.1 - 5e-20 71.2 5.5 8e-20 70.6 5.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ClpS PF02617.17 EAX89630.1 - 0.00015 21.5 0.3 0.00021 21.0 0.3 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Bap31 PF05529.12 EAX89630.1 - 0.25 11.2 2.5 0.33 10.8 2.4 1.3 1 1 0 1 1 1 0 Bap31/Bap29 transmembrane region ATG16 PF08614.11 EAX89631.1 - 0.0029 17.9 16.6 0.16 12.2 6.4 2.1 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) RTBV_P46 PF06216.11 EAX89631.1 - 0.035 13.0 0.3 0.054 12.4 0.3 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Elf4 PF07011.11 EAX89631.1 - 0.042 13.8 2.5 0.051 13.5 0.1 2.3 2 1 0 2 2 2 0 Early Flowering 4 domain CorA PF01544.18 EAX89631.1 - 0.061 12.6 7.5 0.041 13.2 1.4 2.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein AIP3 PF03915.13 EAX89631.1 - 0.11 11.5 14.4 0.58 9.2 14.3 1.9 1 1 0 1 1 1 0 Actin interacting protein 3 Dynamin_N PF00350.23 EAX89631.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.1 1 1 0 2 2 2 0 Dynamin family DUF848 PF05852.11 EAX89631.1 - 0.25 11.5 10.0 1.2 9.2 2.4 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Filament PF00038.21 EAX89631.1 - 0.3 10.6 16.5 0.33 10.5 4.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein Latarcin PF10279.9 EAX89631.1 - 2.9 8.4 10.5 1.8 9.0 0.4 2.6 2 1 0 2 2 2 0 Latarcin precursor CCDC-167 PF15188.6 EAX89631.1 - 5.4 7.4 16.9 0.48 10.8 4.5 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 YgaB PF14182.6 EAX89631.1 - 7.5 7.0 13.7 0.59 10.6 3.1 3.3 2 2 1 3 3 3 0 YgaB-like protein MULE PF10551.9 EAX89632.1 - 2.9e-11 43.6 1.2 3.8e-11 43.3 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain FLYWCH PF04500.16 EAX89632.1 - 0.11 12.6 2.3 0.22 11.7 2.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAS_N PF17828.1 EAX89633.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX89634.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX89634.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX89634.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX89634.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX89635.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX89635.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tho2 PF11262.8 EAX89637.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX89637.1 - 0.072 13.8 0.7 0.13 13.0 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX89637.1 - 0.39 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family EpuA PF11772.8 EAX89638.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4795 PF16043.5 EAX89638.1 - 0.07 12.7 5.8 0.51 9.9 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAX89638.1 - 0.17 12.2 7.4 0.23 11.8 0.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1947) PI3_PI4_kinase PF00454.27 EAX89640.1 - 1.9e-52 178.6 0.9 4.9e-52 177.2 0.9 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EAX89640.1 - 7.8e-17 61.7 0.1 7.8e-17 61.7 0.1 5.8 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) FATC PF02260.20 EAX89640.1 - 1.9e-12 46.8 0.4 6.6e-12 45.0 0.0 2.3 2 0 0 2 2 1 1 FATC domain HEAT_2 PF13646.6 EAX89640.1 - 0.00013 22.3 0.4 0.2 12.1 0.0 3.6 2 1 1 3 3 2 2 HEAT repeats FAT PF02259.23 EAX89640.1 - 0.0013 18.1 8.6 0.0033 16.7 3.4 3.5 2 1 1 3 3 3 1 FAT domain TPR_1 PF00515.28 EAX89640.1 - 0.0072 16.1 0.7 0.088 12.7 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat CNOT11 PF10155.9 EAX89640.1 - 0.023 14.8 0.3 0.023 14.8 0.3 5.3 6 0 0 6 6 6 0 CCR4-NOT transcription complex subunit 11 HEAT PF02985.22 EAX89640.1 - 0.035 14.3 5.8 3.8 8.0 0.1 5.4 4 0 0 4 4 4 0 HEAT repeat TPR_2 PF07719.17 EAX89640.1 - 0.053 13.7 1.4 1 9.7 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat RIX1 PF08167.12 EAX89640.1 - 0.059 13.1 0.0 0.059 13.1 0.0 4.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Utp12 PF04003.12 EAX89640.1 - 0.1 12.9 0.4 1.3 9.3 0.0 3.2 2 0 0 2 2 2 0 Dip2/Utp12 Family TPR_19 PF14559.6 EAX89640.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NUC173 PF08161.12 EAX89640.1 - 0.24 11.0 5.8 0.28 10.8 0.2 3.7 4 0 0 4 4 4 0 NUC173 domain TPR_17 PF13431.6 EAX89640.1 - 0.36 11.3 4.2 0.62 10.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAX89640.1 - 4 7.2 6.8 1.7 8.4 0.2 3.4 4 0 0 4 4 4 0 TPR repeat Porin_4 PF13609.6 EAX89641.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Gram-negative porin SPDY PF03771.16 EAX89641.1 - 0.033 14.1 0.5 0.09 12.7 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF317) DUF4108 PF13390.6 EAX89642.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX89643.1 - 0.45 10.4 3.7 0.81 9.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX89644.1 - 1.7e-06 27.7 2.7 1.7e-06 27.7 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89644.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89644.1 - 4.1e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89644.1 - 0.00015 21.8 3.3 0.00036 20.6 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89644.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX89644.1 - 0.0013 18.5 0.5 0.0062 16.2 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX89644.1 - 0.0015 18.3 0.8 0.0029 17.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX89644.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89644.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89644.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89644.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX89644.1 - 0.12 12.3 0.6 2.1 8.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX89644.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX89645.1 - 4.6e-38 129.5 0.3 1.2e-37 128.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX89645.1 - 0.023 14.8 0.4 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) RPA_C PF08784.11 EAX89646.1 - 0.0005 20.7 0.0 0.00079 20.1 0.0 1.3 1 1 0 1 1 1 1 Replication protein A C terminal PqqD PF05402.12 EAX89646.1 - 0.046 14.0 0.4 13 6.2 0.1 2.2 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Beta_helix PF13229.6 EAX89647.1 - 0.051 13.4 0.4 0.085 12.7 0.4 1.5 1 1 0 1 1 1 0 Right handed beta helix region PDEase_I PF00233.19 EAX89648.1 - 6.6e-79 265.0 2.6 6.6e-79 265.0 2.6 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX89648.1 - 1.3e-36 126.1 0.0 3.2e-17 63.4 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX89648.1 - 1.2e-30 106.6 0.0 5e-10 39.8 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 EAX89648.1 - 5.3e-14 52.7 0.0 8.9e-05 22.8 0.0 3.6 3 0 0 3 3 3 2 GAF domain SpoVT_C PF15714.5 EAX89648.1 - 0.00032 20.8 0.1 0.13 12.4 0.0 3.1 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor Pkinase PF00069.25 EAX89649.1 - 1.7e-13 50.6 0.1 9.2e-07 28.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89649.1 - 7.9e-11 41.7 0.0 9e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Metal_resist PF13801.6 EAX89649.1 - 0.068 13.4 0.8 0.12 12.6 0.8 1.3 1 0 0 1 1 1 0 Heavy-metal resistance PSP PF04046.16 EAX89650.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89651.1 - 0.048 14.2 5.7 11 7.2 0.2 3.5 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX89653.1 - 0.075 13.0 11.1 0.12 12.4 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX89654.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX89655.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX89655.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX89656.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX89656.1 - 0.059 13.4 0.2 0.076 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) T5orf172 PF10544.9 EAX89657.1 - 7e-07 29.7 0.2 1.9e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX89657.1 - 0.0074 15.8 0.5 0.081 12.4 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain DUF3839 PF12943.7 EAX89658.1 - 7.8e-156 516.7 13.8 9.6e-156 516.4 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX89658.1 - 0.032 14.7 0.9 0.15 12.5 0.2 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX89658.1 - 0.15 12.5 5.0 1.9 9.0 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX89658.1 - 0.17 11.7 1.3 0.43 10.4 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX89658.1 - 0.55 10.6 3.8 15 6.0 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX89658.1 - 0.78 10.3 4.7 0.3 11.7 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Lipid_DES PF08557.10 EAX89659.1 - 1.5 8.4 4.4 0.45 10.1 1.0 1.9 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Myb_DNA-binding PF00249.31 EAX89660.1 - 9.6e-26 89.7 0.6 9.8e-14 51.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89660.1 - 5.2e-18 65.1 4.7 6.4e-12 45.5 3.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX89660.1 - 2.7e-06 27.5 1.0 4.9e-06 26.6 0.8 1.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX89660.1 - 5.7e-06 26.1 0.5 1.2e-05 25.1 0.5 1.5 1 0 0 1 1 1 1 Myb DNA-binding like SLIDE PF09111.10 EAX89660.1 - 0.00042 20.3 0.1 0.24 11.4 0.2 2.6 1 1 1 2 2 2 2 SLIDE EcoR124_C PF12008.8 EAX89660.1 - 0.024 14.3 0.5 0.033 13.8 0.5 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Lipase_3 PF01764.25 EAX89661.1 - 8.4e-17 61.4 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EAX89661.1 - 0.00022 20.6 0.0 0.00042 19.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX89661.1 - 0.0065 17.1 0.0 0.0079 16.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EAX89661.1 - 0.021 14.4 0.0 0.2 11.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.13 EAX89661.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 EAX89661.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 EAX89661.1 - 0.086 12.0 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 EAX89661.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 EAX89661.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TFIIA PF03153.13 EAX89662.1 - 0.056 13.4 0.1 0.057 13.4 0.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ECSCR PF15820.5 EAX89662.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LRR_5 PF13306.6 EAX89663.1 - 4e-96 317.8 54.8 1e-19 70.7 3.2 7.0 3 2 2 7 7 7 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89663.1 - 2.8e-20 71.8 0.0 0.00029 20.5 0.0 9.6 9 2 2 11 11 11 5 Leucine rich repeat LRR_4 PF12799.7 EAX89663.1 - 6.5e-10 39.1 10.6 0.21 12.0 0.0 8.5 6 2 0 6 6 6 3 Leucine Rich repeats (2 copies) hSac2 PF12456.8 EAX89663.1 - 0.057 13.1 0.6 34 4.2 0.0 3.7 2 1 2 4 4 4 0 Inositol phosphatase Rrp40_N PF18311.1 EAX89663.1 - 0.19 11.7 0.0 0.85 9.6 0.0 2.1 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain LRR_5 PF13306.6 EAX89664.1 - 4.3e-96 317.7 103.7 1.5e-24 86.4 11.9 6.5 4 1 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89664.1 - 1.5e-13 50.3 6.1 0.0017 18.1 0.1 7.6 6 2 1 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAX89664.1 - 2.4e-08 34.1 4.7 0.051 14.0 0.0 5.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Transcrip_act PF04949.13 EAX89666.1 - 0.11 12.4 2.2 0.35 10.7 1.3 2.0 1 1 1 2 2 2 0 Transcriptional activator SNARE PF05739.19 EAX89667.1 - 0.058 13.4 0.7 0.12 12.4 0.7 1.5 1 0 0 1 1 1 0 SNARE domain LRR_5 PF13306.6 EAX89668.1 - 4.2e-99 327.4 54.9 2.3e-30 105.2 2.8 5.8 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89668.1 - 9.8e-25 86.1 0.0 3.1e-06 26.8 0.0 7.9 6 3 3 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 EAX89668.1 - 1.9e-06 28.1 9.4 0.05 14.1 0.0 6.4 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) Crystall_2 PF09076.10 EAX89668.1 - 0.027 14.3 1.8 14 5.7 0.0 3.9 3 0 0 3 3 3 0 Beta/Gamma crystallin HTH_39 PF14090.6 EAX89668.1 - 0.22 11.3 0.3 11 5.9 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain zf-Tim10_DDP PF02953.15 EAX89668.1 - 0.72 9.5 8.6 3.8 7.2 0.6 4.1 3 2 1 4 4 4 0 Tim10/DDP family zinc finger DUF3839 PF12943.7 EAX89669.1 - 9.1e-60 202.1 3.9 1e-59 201.9 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX89671.1 - 0.066 13.8 4.9 12 7.1 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89672.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4576 PF15144.6 EAX89673.1 - 0.1 12.5 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) GHD PF17834.1 EAX89673.1 - 0.22 11.6 2.8 0.28 11.3 0.4 2.5 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Gly-zipper_Omp PF13488.6 EAX89674.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX89674.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX89674.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX89676.1 - 5.1e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX89676.1 - 0.0051 16.8 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX89676.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 C2 PF00168.30 EAX89678.1 - 0.032 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain C2 PF00168.30 EAX89679.1 - 0.029 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 C2 domain malic PF00390.19 EAX89680.1 - 2.7e-30 105.5 0.1 1.5e-21 77.0 0.1 2.7 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 EAX89680.1 - 4.5e-08 32.7 2.6 6.2e-08 32.2 2.6 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain ThiF PF00899.21 EAX89680.1 - 1.4 8.3 4.2 0.95 8.8 2.0 1.8 1 1 2 3 3 3 0 ThiF family Malic_M PF03949.15 EAX89681.1 - 2e-18 66.6 1.9 3.7e-17 62.5 1.9 2.0 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 EAX89681.1 - 0.05 12.9 0.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain E2F_TDP PF02319.20 EAX89682.1 - 1.5e-14 53.8 0.1 5.8e-08 32.7 0.0 2.6 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain CAMSAP_CKK PF08683.11 EAX89683.1 - 1.3e-15 57.6 0.2 3.8e-15 56.1 0.2 1.8 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH_2 PF06294.11 EAX89683.1 - 0.00069 19.7 0.0 0.0052 16.9 0.0 2.6 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EAX89683.1 - 0.0011 18.8 0.0 0.0035 17.1 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain TMEM131_like PF12371.8 EAX89684.1 - 1.2e-05 25.4 6.4 0.02 15.1 0.1 5.1 6 0 0 6 6 6 2 Transmembrane protein 131-like Glyco_hydro_43 PF04616.14 EAX89684.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 DUF4108 PF13390.6 EAX89685.1 - 3.7e-56 189.0 5.4 4.1e-56 188.9 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX89686.1 - 7.2 6.6 6.4 16 5.5 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX89687.1 - 6.2e-07 29.1 2.5 6.2e-07 29.1 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89687.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX89687.1 - 5.6e-05 23.0 0.3 0.48 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX89687.1 - 0.00014 21.9 3.2 0.00032 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX89687.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89687.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89687.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89687.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89687.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX89687.1 - 0.089 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX89687.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX89687.1 - 0.39 11.0 4.4 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX89688.1 - 8.5e-40 135.1 1.2 1.3e-39 134.5 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX89688.1 - 0.018 15.6 1.2 0.036 14.7 0.0 2.1 3 0 0 3 3 3 0 Parathyroid hormone family T5orf172 PF10544.9 EAX89689.1 - 6.1e-07 29.9 0.3 1.2e-06 29.0 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Fringe PF02434.16 EAX89690.1 - 5e-06 26.2 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EAX89690.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase GPS2_interact PF15784.5 EAX89692.1 - 0.049 14.1 1.4 0.068 13.6 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GPS2_interact PF15784.5 EAX89693.1 - 0.038 14.4 2.3 0.039 14.4 2.3 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Ras PF00071.22 EAX89695.1 - 3.2e-54 182.9 0.1 3.7e-54 182.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89695.1 - 5e-33 113.9 0.0 7.5e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89695.1 - 5.8e-15 55.2 0.0 7.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX89695.1 - 1.3e-05 24.7 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX89695.1 - 2.2e-05 24.5 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX89695.1 - 0.00074 19.1 0.0 0.0067 16.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX89695.1 - 0.0033 17.4 0.0 1.2 9.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EAX89695.1 - 0.035 13.6 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B STALD PF18185.1 EAX89695.1 - 0.06 12.7 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family TniB PF05621.11 EAX89695.1 - 0.081 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 EAX89695.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit LRR_5 PF13306.6 EAX89696.1 - 1.2e-72 241.9 60.6 8.7e-22 77.5 5.3 4.2 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89696.1 - 1e-07 31.6 0.1 0.17 11.6 0.0 6.1 5 1 2 7 7 7 4 Leucine rich repeat Guanylate_cyc PF00211.20 EAX89697.1 - 1.6e-42 145.2 1.5 2.2e-42 144.8 0.1 1.9 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 EAX89697.1 - 1.4e-07 31.5 0.2 5.9e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EAX89697.1 - 1.7e-07 31.5 0.9 1.2e-06 28.7 0.4 2.4 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EAX89697.1 - 4.1e-06 26.7 0.1 4e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 PAS domain PAS_4 PF08448.10 EAX89697.1 - 0.00077 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Guanylate_cyc PF00211.20 EAX89698.1 - 5.9e-43 146.6 0.3 2.9e-42 144.4 0.1 2.3 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX89698.1 - 7.2e-09 35.8 0.2 2.3e-08 34.2 0.2 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX89698.1 - 0.00013 21.9 0.0 0.00046 20.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX89698.1 - 0.0031 17.7 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold TPR_17 PF13431.6 EAX89698.1 - 0.045 14.1 1.2 12 6.6 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat PAS_8 PF13188.7 EAX89698.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain TMP PF05017.14 EAX89699.1 - 0.063 13.9 8.5 6.8 7.8 0.8 3.5 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX89699.1 - 3 7.8 7.7 3.2 7.7 7.7 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX89700.1 - 0.075 13.5 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89701.1 - 2.5e-61 203.6 45.1 5.3e-31 106.5 14.3 6.4 4 2 3 7 7 7 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX89701.1 - 0.035 14.0 0.7 0.057 13.3 0.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX89701.1 - 0.041 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) SSP160 PF06933.11 EAX89702.1 - 4.9 5.2 19.3 5.1 5.2 19.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3839 PF12943.7 EAX89703.1 - 1.7e-155 515.5 12.9 2.2e-155 515.2 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89703.1 - 2.3 8.7 6.1 4.8 7.7 0.3 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Homeobox_KN PF05920.11 EAX89704.1 - 1.6e-09 37.5 0.1 5.3e-09 35.8 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAX89704.1 - 0.015 15.1 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 Homeodomain Hid1 PF12722.7 EAX89704.1 - 1.5 6.8 18.7 2 6.4 18.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARA70 PF12489.8 EAX89706.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Herpes_IE2_3 PF03361.14 EAX89707.1 - 0.015 15.2 1.2 0.32 10.8 0.2 2.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Toxin_R_bind_C PF07951.12 EAX89707.1 - 0.032 13.9 4.3 0.087 12.5 0.7 2.7 2 1 1 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding Flavi_capsid PF01003.19 EAX89707.1 - 0.33 10.7 3.4 0.38 10.5 0.1 2.7 3 0 0 3 3 3 0 Flavivirus capsid protein C PPP5 PF08321.12 EAX89707.1 - 0.5 10.7 8.5 1.9 8.8 1.0 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region DUF4795 PF16043.5 EAX89708.1 - 0.00082 19.0 9.0 1.6 8.3 0.2 3.5 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) GST_C PF00043.25 EAX89708.1 - 0.0015 18.7 2.4 2.6 8.3 0.0 3.8 1 1 2 3 3 3 2 Glutathione S-transferase, C-terminal domain ESAG1 PF03238.13 EAX89708.1 - 0.0053 16.2 6.1 0.6 9.5 0.2 3.4 1 1 2 3 3 3 2 ESAG protein PH_3 PF14593.6 EAX89708.1 - 0.081 13.0 3.7 3.2 7.9 0.1 3.2 3 0 0 3 3 3 0 PH domain DUF5348 PF17295.2 EAX89708.1 - 0.62 10.0 8.2 23 5.0 1.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5348) Ribosomal_L12 PF00542.19 EAX89708.1 - 1.1 9.6 4.6 37 4.8 0.0 3.4 3 1 1 4 4 4 0 Ribosomal protein L7/L12 C-terminal domain KilA-N PF04383.13 EAX89709.1 - 1.2e-23 83.1 0.8 1.5e-23 82.7 0.8 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3038 PF11237.8 EAX89709.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF3839 PF12943.7 EAX89710.1 - 1.1e-78 264.1 9.5 1.4e-78 263.7 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF702 PF05142.12 EAX89711.1 - 0.024 15.1 0.0 91 3.5 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF702) DUF641 PF04859.12 EAX89714.1 - 0.016 15.5 2.6 0.026 14.9 2.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MPS2 PF17060.5 EAX89714.1 - 0.041 13.2 2.9 0.044 13.0 2.9 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 bZIP_1 PF00170.21 EAX89714.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.6 2 1 1 3 3 3 0 bZIP transcription factor AbiJ_NTD4 PF18863.1 EAX89715.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX89715.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein DUF3839 PF12943.7 EAX89716.1 - 1.1e-133 444.1 12.2 1.3e-133 443.9 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89716.1 - 0.017 15.6 1.8 1.2 9.6 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX89718.1 - 7.1e-21 74.0 23.4 3.6e-16 59.0 1.8 5.3 6 1 0 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX89718.1 - 0.014 15.0 1.4 0.014 15.0 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX89718.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX89719.1 - 0.022 15.2 0.5 0.045 14.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ORF45 PF17620.2 EAX89720.1 - 0.079 13.1 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function EF-hand_6 PF13405.6 EAX89722.1 - 4e-17 60.6 5.0 0.29 11.2 0.0 8.0 7 0 0 7 7 7 6 EF-hand domain EF-hand_1 PF00036.32 EAX89722.1 - 5.2e-09 35.0 0.0 0.22 11.2 0.0 5.9 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EAX89722.1 - 3.2e-08 33.9 8.8 2.8 8.5 0.0 7.4 7 0 0 7 7 7 4 EF-hand domain pair DUF2666 PF10869.8 EAX89722.1 - 0.00047 20.4 2.5 7.8 6.7 0.0 5.5 7 0 0 7 7 7 2 Protein of unknown function (DUF2666) EF-hand_11 PF08976.11 EAX89722.1 - 0.0011 19.9 16.2 1 10.3 0.1 6.3 7 0 0 7 7 7 2 EF-hand domain DUF5580 PF17743.1 EAX89722.1 - 0.01 14.4 2.0 0.18 10.3 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5580) RST PF12174.8 EAX89722.1 - 0.018 14.9 0.7 33 4.5 0.0 5.1 4 0 0 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain DUF2087 PF09860.9 EAX89722.1 - 0.096 12.8 0.1 0.36 11.0 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF563 PF04577.14 EAX89723.1 - 1.7e-25 90.4 0.0 2.1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3781 PF12636.7 EAX89724.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAX89725.1 - 4.8e-66 221.9 13.2 1.4e-64 217.2 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX89725.1 - 0.097 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX89726.1 - 4.8e-153 507.5 11.0 6.2e-153 507.2 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX89726.1 - 1.1 9.8 4.3 4.2 7.9 0.4 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4618 PF15397.6 EAX89728.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Pkinase PF00069.25 EAX89729.1 - 1.4e-60 204.9 0.4 2.1e-60 204.3 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89729.1 - 2.2e-39 135.3 0.1 2.9e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89729.1 - 3.1e-06 26.7 0.0 7.3e-05 22.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EAX89729.1 - 0.00037 20.5 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX89729.1 - 0.00084 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX89729.1 - 0.0045 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX89729.1 - 0.0059 15.6 0.6 0.37 9.7 0.1 2.2 1 1 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 EAX89729.1 - 0.016 14.8 0.7 0.096 12.3 0.1 2.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAX89729.1 - 0.017 14.7 0.3 0.084 12.5 0.1 2.0 1 1 1 2 2 2 0 RIO1 family PIP49_C PF12260.8 EAX89729.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 EAX89730.1 - 8.6e-57 192.5 0.2 1e-56 192.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89730.1 - 1.2e-34 119.8 0.0 1.3e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89730.1 - 5.2e-07 29.3 0.0 1.6e-05 24.4 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX89730.1 - 8.3e-06 25.3 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX89730.1 - 0.00099 18.1 0.3 0.0014 17.7 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX89730.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX89730.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 EAX89730.1 - 0.0024 17.5 0.1 0.0039 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 FTA2 PF13095.6 EAX89730.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAX89730.1 - 0.078 12.5 0.9 0.11 12.0 0.9 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NARG2_C PF10505.9 EAX89730.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus YozE_SAM_like PF06855.12 EAX89732.1 - 0.077 13.2 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 YozE SAM-like fold Pkinase PF00069.25 EAX89733.1 - 1.8e-56 191.4 0.1 2.3e-56 191.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89733.1 - 4.6e-35 121.2 0.0 5.2e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89733.1 - 0.00037 19.9 0.0 0.02 14.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EAX89733.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX89733.1 - 0.0048 15.7 0.0 0.0068 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 EAX89733.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RIO1 PF01163.22 EAX89733.1 - 0.019 14.6 0.1 0.9 9.1 0.0 2.0 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 EAX89733.1 - 0.022 14.4 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 EAX89733.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 EAX89733.1 - 0.034 13.5 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PglD_N PF17836.1 EAX89733.1 - 0.037 14.7 0.0 0.085 13.5 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain DUF4728 PF15860.5 EAX89735.1 - 1.9 9.2 0.0 1.9 9.2 0.0 3.5 3 2 2 5 5 5 0 Domain of unknown function (DUF4728) LRR_5 PF13306.6 EAX89736.1 - 1.6e-67 225.3 53.7 1.4e-26 93.0 15.7 5.0 1 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) DUF1125 PF06563.11 EAX89736.1 - 0.031 14.2 0.7 15 5.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) LRR_5 PF13306.6 EAX89737.1 - 6.5e-156 511.1 188.5 4.9e-27 94.4 11.5 9.8 4 2 6 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89737.1 - 1.9e-23 82.0 22.3 9.8e-06 25.2 0.0 12.0 11 3 3 14 14 14 5 Leucine rich repeat DUF1871 PF08958.10 EAX89737.1 - 0.019 15.3 0.2 0.074 13.4 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) Microcin PF03526.13 EAX89737.1 - 0.034 13.9 0.2 0.034 13.9 0.2 6.9 8 1 0 8 8 8 0 Colicin E1 (microcin) immunity protein MPTase-PolyVal PF18818.1 EAX89737.1 - 0.1 12.6 3.2 23 5.0 0.1 4.8 5 2 2 7 7 7 0 Metallopeptidase superfamily domain DUF2448 PF10476.9 EAX89737.1 - 0.16 11.8 1.2 3.2 7.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function C-terminus (DUF2448) FNIP PF05725.12 EAX89737.1 - 0.36 11.0 28.1 1.3 9.3 0.7 9.3 7 2 0 7 7 7 0 FNIP Repeat Cas6b_C PF17262.2 EAX89737.1 - 5.8 7.0 6.8 7.2 6.8 0.1 4.1 5 0 0 5 5 5 0 Cas6b C-terminal domain Gly_rich PF12810.7 EAX89738.1 - 9.8e-29 101.0 29.9 1.2e-28 100.7 29.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX89739.1 - 6.8e-29 101.5 27.5 8e-29 101.3 27.5 1.0 1 0 0 1 1 1 1 Glycine rich protein PTR PF12789.7 EAX89741.1 - 2.1e-30 104.6 9.3 2.1e-30 104.6 9.3 4.2 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX89741.1 - 0.076 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TbpB_A PF17484.2 EAX89741.1 - 0.7 10.6 9.1 0.88 10.3 5.3 2.8 2 2 0 2 2 2 0 N-Lobe handle Tf-binding protein B DUF240 PF03086.14 EAX89741.1 - 1.8 8.5 6.9 1.6 8.7 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAX89742.1 - 0.088 13.3 0.5 0.18 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX89743.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89744.1 - 0.039 13.8 1.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PSP MULE PF10551.9 EAX89745.1 - 2.4e-10 40.7 1.5 3.1e-10 40.3 0.2 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX89745.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Telomere_reg-2 PF10193.9 EAX89746.1 - 0.026 15.0 1.4 0.082 13.4 0.1 2.5 3 1 0 3 3 3 0 Telomere length regulation protein DUF563 PF04577.14 EAX89747.1 - 5.7e-27 95.2 0.1 1.1e-26 94.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Clenterotox PF03505.14 EAX89747.1 - 0.092 12.3 1.2 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Clostridium enterotoxin Pkinase PF00069.25 EAX89748.1 - 2.8e-57 194.1 0.0 3.5e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89748.1 - 1.2e-35 123.0 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89748.1 - 5.2e-06 26.0 0.0 6.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX89748.1 - 0.006 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EAX89748.1 - 0.029 13.3 0.0 0.072 12.0 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EAX89748.1 - 0.21 11.5 0.0 1.4 8.8 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family SHIPPO-rpt PF07004.12 EAX89749.1 - 7.6e-13 48.7 12.5 9.2e-06 26.3 2.0 4.7 4 0 0 4 4 4 3 Sperm-tail PG-rich repeat CDC50 PF03381.15 EAX89750.1 - 2.4e-62 211.0 0.6 2.9e-62 210.8 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF5305 PF17231.2 EAX89750.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) UL41A PF17591.2 EAX89750.1 - 3.8 7.7 7.5 6.2 7.0 1.3 2.4 2 0 0 2 2 2 0 Herpesvirus UL41A EVI2A PF05399.11 EAX89750.1 - 3.8 7.0 5.6 9.6 5.7 0.2 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) UCH PF00443.29 EAX89751.1 - 2.8e-52 177.8 0.2 4.6e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX89751.1 - 3.3e-16 59.8 6.5 4.9e-15 55.9 6.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX89751.1 - 9.3e-14 51.8 2.0 2.1e-12 47.5 0.4 2.6 2 0 0 2 2 2 1 DUSP domain FAR1 PF03101.15 EAX89753.1 - 0.011 16.4 0.1 0.021 15.5 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DDE_1 PF03184.19 EAX89754.1 - 1.3e-16 60.7 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NDUFB10 PF10249.9 EAX89755.1 - 0.061 13.8 0.6 7.8 7.0 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Pkinase PF00069.25 EAX89756.1 - 9.6e-56 189.1 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89756.1 - 1.1e-29 103.5 0.0 1.4e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89756.1 - 2e-07 30.6 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX89756.1 - 0.00065 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Prenyltrans PF00432.21 EAX89756.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Kdo PF06293.14 EAX89756.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX89756.1 - 0.1 12.2 0.4 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAX89757.1 - 3.2e-46 157.8 0.0 4.8e-46 157.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89757.1 - 1.9e-26 92.9 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89757.1 - 0.0098 15.2 0.1 0.038 13.3 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX89757.1 - 0.071 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX89757.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EAX89758.1 - 1.3e-24 86.7 0.0 1.5e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89758.1 - 8.1e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89758.1 - 8.7e-11 41.6 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX89758.1 - 2.3e-08 33.8 0.0 3e-07 30.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX89758.1 - 1.8e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX89758.1 - 0.0096 15.8 0.1 0.024 14.5 0.1 1.7 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EAX89758.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EAX89758.1 - 0.037 14.1 0.1 0.084 12.9 0.1 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 EAX89758.1 - 0.12 12.2 0.0 4 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 EAX89758.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.4 1 1 0 1 1 1 0 TIR domain TniB PF05621.11 EAX89758.1 - 0.15 11.4 0.0 0.92 8.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein WD40 PF00400.32 EAX89759.1 - 1.3e-18 67.0 14.1 0.0013 19.5 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX89759.1 - 1.9e-13 50.5 0.5 0.00028 21.1 0.1 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_8 PF01501.20 EAX89760.1 - 2.2e-07 30.7 0.8 2.2e-07 30.7 0.8 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF3342 PF11822.8 EAX89761.1 - 0.17 12.1 4.5 0.29 11.4 0.3 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3342) DDE_1 PF03184.19 EAX89762.1 - 5.3e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_Rpb6 PF01192.22 EAX89763.1 - 7.9e-14 51.3 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 EAX89763.1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) RIB43A PF05914.12 EAX89764.1 - 8.2e-62 209.1 75.3 1.1e-61 208.7 75.3 1.0 1 0 0 1 1 1 1 RIB43A TPH PF13868.6 EAX89764.1 - 2.3 6.7 115.6 0.049 12.1 31.0 3.7 3 2 0 3 3 3 0 Trichohyalin-plectin-homology domain Pkinase PF00069.25 EAX89765.1 - 8.2e-69 231.9 0.0 1e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89765.1 - 6.4e-39 133.8 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX89765.1 - 1.7e-06 28.5 0.0 3.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX89765.1 - 2.5e-06 27.0 0.0 4.5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX89765.1 - 0.0042 16.1 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX89765.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 EAX89765.1 - 0.029 15.1 1.0 0.087 13.5 1.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 EAX89765.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSP70 PF00012.20 EAX89766.1 - 1.5e-31 109.3 0.3 1.8e-31 109.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX89766.1 - 0.0035 16.2 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Trimer_CC PF08954.11 EAX89766.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Trimerisation motif ABC_membrane PF00664.23 EAX89767.1 - 1.1e-42 146.6 22.7 1.5e-42 146.1 22.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX89767.1 - 3.1e-34 118.4 0.1 7.7e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAX89767.1 - 1.9e-08 34.0 3.1 2.5e-07 30.4 0.1 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAX89767.1 - 0.00027 20.8 1.7 0.00047 20.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX89767.1 - 0.00068 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EAX89767.1 - 0.0026 18.1 0.3 0.024 14.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain NicO PF03824.16 EAX89767.1 - 0.0041 16.5 6.8 0.012 15.0 0.0 3.1 3 0 0 3 3 3 1 High-affinity nickel-transport protein DUF4094 PF13334.6 EAX89767.1 - 0.0055 17.1 1.6 0.44 11.0 0.0 3.4 4 0 0 4 4 3 1 Domain of unknown function (DUF4094) AAA_16 PF13191.6 EAX89767.1 - 0.0062 16.9 0.6 0.024 15.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EAX89767.1 - 0.018 14.9 0.0 1.7 8.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX89767.1 - 0.031 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EAX89767.1 - 0.056 13.5 0.2 8.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Sec20 PF03908.13 EAX89767.1 - 0.11 12.4 0.7 0.48 10.4 0.2 2.4 2 0 0 2 2 2 0 Sec20 AAA_30 PF13604.6 EAX89767.1 - 0.18 11.5 0.0 0.69 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 EAX89768.1 - 2.4e-40 138.9 20.7 3.3e-40 138.5 20.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX89768.1 - 3.2e-06 27.7 0.3 6.5e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EAX89768.1 - 0.0022 17.7 1.6 0.0024 17.6 0.2 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAX89768.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF5392 PF17370.2 EAX89768.1 - 0.047 13.8 5.2 2.6 8.1 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5392) Cadherin_C_2 PF16492.5 EAX89768.1 - 0.15 12.9 0.6 0.47 11.2 0.6 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal AAA_23 PF13476.6 EAX89768.1 - 0.35 11.3 1.3 0.42 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain 2TM PF13239.6 EAX89768.1 - 4 7.8 14.3 0.18 12.1 0.9 3.2 3 0 0 3 3 3 0 2TM domain ABC_tran PF00005.27 EAX89769.1 - 4.2e-15 56.5 0.0 6.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX89769.1 - 0.028 13.9 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain CAMSAP_CKK PF08683.11 EAX89769.1 - 0.03 14.5 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated ABC_membrane PF00664.23 EAX89770.1 - 2.5e-41 142.2 22.9 3.4e-41 141.7 22.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX89770.1 - 1.8e-32 112.7 0.0 6.3e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAX89770.1 - 4.7e-08 32.7 0.0 3.4e-07 29.9 0.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAX89770.1 - 9.4e-05 22.3 1.1 0.00043 20.1 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX89770.1 - 0.00074 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EAX89770.1 - 0.0032 17.7 0.0 0.048 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAX89770.1 - 0.0071 16.7 0.4 0.029 14.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF4094 PF13334.6 EAX89770.1 - 0.0081 16.6 1.0 0.04 14.3 0.0 2.6 2 1 1 3 3 2 1 Domain of unknown function (DUF4094) DUF1003 PF06210.11 EAX89770.1 - 0.013 15.6 4.7 0.26 11.4 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) AAA_29 PF13555.6 EAX89770.1 - 0.04 13.7 0.4 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAX89770.1 - 0.052 13.6 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase NicO PF03824.16 EAX89770.1 - 0.19 11.1 14.9 0.044 13.1 0.9 3.0 2 1 0 3 3 3 0 High-affinity nickel-transport protein ABC_membrane PF00664.23 EAX89771.1 - 1e-41 143.5 18.8 1.4e-41 143.0 18.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX89771.1 - 7.3e-38 130.2 0.1 1.3e-37 129.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 EAX89771.1 - 0.00013 21.8 0.2 0.00022 21.1 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAX89771.1 - 0.00042 20.0 0.1 0.00097 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAX89771.1 - 0.0023 18.3 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EAX89771.1 - 0.0036 16.6 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EAX89771.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EAX89771.1 - 0.019 14.4 3.5 0.84 9.0 0.2 2.4 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EAX89771.1 - 0.026 14.2 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein G-alpha PF00503.20 EAX89771.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EAX89771.1 - 0.049 13.9 0.1 0.17 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX89771.1 - 0.069 12.7 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EAX89771.1 - 0.074 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAX89771.1 - 0.16 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX89771.1 - 0.17 11.9 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EAX89771.1 - 0.2 12.1 1.1 2.5 8.5 0.4 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EAX89772.1 - 9.9e-67 225.1 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89772.1 - 3.2e-32 111.8 0.0 4.3e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89772.1 - 4.7e-05 22.8 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX89772.1 - 0.002 18.1 0.0 0.063 13.2 0.0 2.6 2 2 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX89772.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX89772.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX89772.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Meiosis_expr PF15163.6 EAX89773.1 - 0.091 13.4 1.3 0.15 12.8 0.4 1.7 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX89773.1 - 0.6 10.1 8.0 0.18 11.7 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Adaptin_N PF01602.20 EAX89774.1 - 0.00071 18.2 0.1 0.0034 16.0 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region DUF1453 PF07301.11 EAX89774.1 - 0.029 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) FOP_dimer PF09398.10 EAX89775.1 - 6.2e-05 23.2 0.3 0.00018 21.7 0.0 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain vATP-synt_E PF01991.18 EAX89776.1 - 5.3e-33 114.1 13.0 6.4e-33 113.9 13.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NUC PF18510.1 EAX89776.1 - 0.02 15.3 3.2 0.029 14.8 3.2 1.1 1 0 0 1 1 1 0 Nuclease domain Flu_B_M2 PF04772.12 EAX89776.1 - 0.035 14.4 2.8 0.055 13.7 2.8 1.3 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) FapA PF03961.13 EAX89776.1 - 0.054 12.1 7.9 0.059 12.0 7.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAF_3 PF13492.6 EAX89776.1 - 0.1 12.9 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 GAF domain XRCC4 PF06632.12 EAX89776.1 - 0.19 10.6 8.5 0.31 9.9 8.4 1.6 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ArlS_N PF18719.1 EAX89776.1 - 0.23 11.7 6.7 0.26 11.5 5.7 1.6 1 1 1 2 2 2 0 ArlS sensor domain PDCD9 PF07147.12 EAX89778.1 - 0.0013 18.0 0.2 0.0015 17.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) SbsC_C PF18058.1 EAX89778.1 - 0.0023 18.1 1.6 0.27 11.5 0.1 2.2 2 0 0 2 2 2 2 SbsC C-terminal domain Glyco_hydro_71 PF03659.14 EAX89778.1 - 0.088 11.6 0.1 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 SLATT_5 PF18160.1 EAX89778.1 - 0.14 11.4 3.5 0.16 11.3 2.9 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 IQ PF00612.27 EAX89779.1 - 1.4e-05 24.4 11.1 0.00038 20.0 2.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Gly_rich PF12810.7 EAX89780.1 - 1.4e-12 48.1 19.0 1.7e-12 47.8 19.0 1.0 1 0 0 1 1 1 1 Glycine rich protein HTH_23 PF13384.6 EAX89781.1 - 1.4e-13 50.2 0.3 1.3e-08 34.4 0.1 2.2 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4 PF04545.16 EAX89781.1 - 3.7e-08 32.8 0.0 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 2 Sigma-70, region 4 Myb_DNA-binding PF00249.31 EAX89781.1 - 5.9e-08 32.8 1.6 3.3e-07 30.4 0.6 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_29 PF13551.6 EAX89781.1 - 9.2e-08 32.0 0.0 0.00044 20.2 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn helix HTH_38 PF13936.6 EAX89781.1 - 1.2e-07 31.3 0.3 0.00036 20.2 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.6 EAX89781.1 - 1.6e-06 27.5 0.1 0.00052 19.5 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EAX89781.1 - 3.2e-06 26.8 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_32 PF13565.6 EAX89781.1 - 4.3e-06 27.3 1.3 3.6e-05 24.3 0.1 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EAX89781.1 - 6.2e-06 26.2 0.1 0.0063 16.6 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.6 EAX89781.1 - 1.3e-05 25.3 0.2 2.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EAX89781.1 - 4e-05 23.4 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 EAX89781.1 - 5.1e-05 23.1 0.8 0.049 13.6 0.1 2.2 2 0 0 2 2 2 2 HTH domain CENP-B_N PF04218.13 EAX89781.1 - 6.1e-05 22.6 0.0 0.0034 17.0 0.0 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_36 PF13730.6 EAX89781.1 - 0.00019 21.3 0.3 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EAX89781.1 - 0.00052 19.8 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF722 PF05263.11 EAX89781.1 - 0.00078 19.7 0.2 0.0012 19.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF722) Sigma70_r4_2 PF08281.12 EAX89781.1 - 0.0011 18.6 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 EAX89781.1 - 0.0019 17.9 0.0 0.051 13.4 0.0 2.4 2 0 0 2 2 2 1 HTH DNA binding domain HTH_35 PF13693.6 EAX89781.1 - 0.0051 16.8 0.1 0.11 12.5 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_Tnp_1 PF01527.20 EAX89781.1 - 0.0057 17.0 0.5 0.013 15.7 0.4 1.6 1 1 1 2 2 2 1 Transposase MarR PF01047.22 EAX89781.1 - 0.0067 16.3 0.1 1.7 8.6 0.1 2.2 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 EAX89781.1 - 0.011 15.7 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Mga PF08280.11 EAX89781.1 - 0.016 15.3 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DUF4817 PF16087.5 EAX89781.1 - 0.017 14.9 1.1 0.13 12.1 1.1 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain (DUF4817) GerE PF00196.19 EAX89781.1 - 0.025 14.1 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family YdaS_antitoxin PF15943.5 EAX89781.1 - 0.028 14.3 0.2 1.7 8.6 0.0 2.4 2 1 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_ISL3 PF13542.6 EAX89781.1 - 0.03 13.7 0.1 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Phage_terminase PF10668.9 EAX89781.1 - 0.034 14.2 0.4 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Phage terminase small subunit HTH_50 PF18024.1 EAX89781.1 - 0.037 13.7 0.2 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 EAX89781.1 - 0.044 13.7 0.7 0.32 10.9 0.3 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 EAX89781.1 - 0.048 13.7 0.1 8 6.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.8 EAX89781.1 - 0.049 13.7 0.2 5.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MarR_2 PF12802.7 EAX89781.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_26 PF13443.6 EAX89781.1 - 0.077 13.4 0.1 6.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 EAX89781.1 - 0.09 13.0 0.6 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 Transposase HTH_31 PF13560.6 EAX89781.1 - 0.096 13.0 0.1 15 6.0 0.2 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 EAX89781.1 - 0.11 12.4 0.1 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Phage antitermination protein Q HTH_40 PF14493.6 EAX89781.1 - 0.13 12.8 0.1 5.7 7.5 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 EAX89781.1 - 0.17 12.0 0.2 11 6.2 0.0 2.9 2 1 0 2 2 2 0 HTH domain HTH_9 PF08221.11 EAX89781.1 - 0.2 11.8 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HMG_CoA_synt_N PF01154.17 EAX89782.1 - 6.3e-65 218.3 0.1 1.1e-64 217.5 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EAX89782.1 - 1.1e-56 192.5 1.2 3.5e-56 190.9 1.2 1.8 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 EAX89782.1 - 0.045 13.9 0.2 1.2 9.4 0.2 2.3 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EAX89782.1 - 0.095 12.6 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ank_5 PF13857.6 EAX89784.1 - 2.7e-18 65.8 2.3 4.7e-10 39.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX89784.1 - 4.9e-15 55.2 0.4 2.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX89784.1 - 9.7e-14 50.2 0.5 1.1e-05 25.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX89784.1 - 8.1e-13 48.8 0.1 1.2e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89784.1 - 3.1e-12 46.7 0.1 7.1e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89784.1 - 0.17 11.9 3.1 0.24 11.4 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) IFT46_B_C PF12317.8 EAX89785.1 - 7.9e-75 251.2 0.1 1e-74 250.9 0.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Folliculin PF11704.8 EAX89787.1 - 0.00058 19.8 0.1 0.00071 19.5 0.1 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport FHA PF00498.26 EAX89789.1 - 0.00046 20.5 0.0 0.00088 19.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain SLIDE PF09111.10 EAX89789.1 - 0.0035 17.3 0.1 0.011 15.7 0.1 1.8 1 1 0 1 1 1 1 SLIDE Ndc80_HEC PF03801.13 EAX89790.1 - 0.01 15.5 0.3 0.017 14.8 0.3 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family Ank_4 PF13637.6 EAX89790.1 - 0.17 12.5 0.1 0.98 10.1 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89791.1 - 3e-42 142.4 7.6 5.7e-09 36.3 0.1 7.5 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89791.1 - 4.1e-40 136.3 21.4 1.3e-16 60.9 0.8 6.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89791.1 - 1.9e-34 116.6 0.2 1.8e-05 25.0 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX89791.1 - 3.2e-31 107.0 5.2 6.2e-09 36.0 0.1 7.0 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89791.1 - 1.2e-29 99.0 4.8 8.3e-05 22.7 0.0 7.8 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 EAX89791.1 - 1.2e-14 54.0 8.1 1.2e-14 54.0 8.1 5.6 2 2 4 6 6 6 4 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EAX89791.1 - 0.02 15.2 0.3 19 5.6 0.0 3.3 2 1 1 3 3 3 0 Ribosomal protein S6 PSP PF04046.16 EAX89792.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89793.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat ABC2_membrane_3 PF12698.7 EAX89795.1 - 6.7e-05 22.2 0.4 8.3e-05 21.8 0.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PHZA_PHZB PF03284.13 EAX89795.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B DUF4366 PF14283.6 EAX89795.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 EAX89795.1 - 0.02 14.3 0.2 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PQQ PF01011.21 EAX89795.1 - 0.021 14.8 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat TMEM154 PF15102.6 EAX89795.1 - 0.022 14.6 1.2 0.035 14.0 1.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 EAX89795.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Rifin OppC_N PF12911.7 EAX89795.1 - 0.088 12.8 0.9 0.18 11.8 0.9 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Orf78 PF06024.12 EAX89795.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) FeoB_associated PF12669.7 EAX89795.1 - 0.12 12.8 2.0 0.19 12.1 2.0 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Peptidase_M8 PF01457.16 EAX89796.1 - 3e-24 85.6 0.1 7.6e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Leishmanolysin ETRAMP PF09716.10 EAX89796.1 - 0.0079 16.2 2.8 0.022 14.8 2.8 1.7 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Mid2 PF04478.12 EAX89796.1 - 0.0093 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.11 EAX89796.1 - 0.075 13.0 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Protocadherin Phage_holin_3_6 PF07332.11 EAX89796.1 - 0.17 12.0 1.1 0.3 11.1 1.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 EAX89799.1 - 1.4e-38 132.8 0.1 1.8e-38 132.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89799.1 - 4.7e-22 78.5 0.1 6.3e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89799.1 - 6.5e-07 29.0 0.0 9.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tim29 PF10171.9 EAX89799.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Seadorna_VP7 PF07387.11 EAX89799.1 - 0.055 12.5 2.5 0.092 11.8 0.1 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 Choline_kinase PF01633.20 EAX89799.1 - 0.075 12.6 0.9 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAX89800.1 - 6.5e-51 173.2 0.0 8.4e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89800.1 - 7.5e-27 94.2 0.0 9.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89800.1 - 1.1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX89800.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAX89800.1 - 0.0031 16.6 0.2 0.0086 15.2 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Prok-E2_E PF14462.6 EAX89800.1 - 0.018 14.8 0.6 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E APH PF01636.23 EAX89800.1 - 0.028 14.3 0.0 0.056 13.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX89800.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SelR PF01641.18 EAX89801.1 - 7.6e-42 142.2 0.3 9.3e-42 141.9 0.3 1.1 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 EAX89801.1 - 0.0035 17.4 1.8 0.14 12.3 0.1 2.7 1 1 1 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 Zn_ribbon_SprT PF17283.2 EAX89801.1 - 0.0062 16.4 2.6 0.31 11.0 0.4 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain Prim_Zn_Ribbon PF08273.12 EAX89801.1 - 0.013 15.7 2.8 0.14 12.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zinc_ribbon_10 PF10058.9 EAX89801.1 - 0.015 15.0 0.7 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 EAX89801.1 - 0.018 14.5 0.3 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 EAX89801.1 - 0.028 14.4 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2757 PF10955.8 EAX89801.1 - 0.057 13.7 0.2 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) DZR PF12773.7 EAX89801.1 - 0.072 13.1 1.3 0.26 11.4 1.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EAX89801.1 - 0.11 12.4 0.4 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit A2L_zn_ribbon PF08792.10 EAX89801.1 - 0.12 12.1 3.1 0.5 10.1 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.14 EAX89801.1 - 0.14 12.5 2.0 0.41 11.0 0.2 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 EAX89801.1 - 0.15 12.3 0.7 0.15 12.3 0.7 2.4 2 1 0 2 2 2 0 Ribosomal protein L37e zf-RRN7 PF11781.8 EAX89801.1 - 0.26 11.0 3.6 0.85 9.4 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_2 PF13240.6 EAX89801.1 - 0.35 10.6 4.2 3 7.7 0.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 EAX89801.1 - 2.2 8.9 7.3 2.8 8.5 1.0 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Pkinase PF00069.25 EAX89803.1 - 7.1e-54 182.9 0.0 9.4e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89803.1 - 1.3e-29 103.3 0.0 2.1e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89803.1 - 2e-07 30.6 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX89803.1 - 0.0036 16.4 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EAX89803.1 - 0.047 13.6 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Y_phosphatase2 PF03162.13 EAX89804.1 - 0.0053 16.3 0.3 0.0087 15.6 0.3 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX89804.1 - 0.0058 16.6 0.8 0.011 15.7 0.1 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 T5orf172 PF10544.9 EAX89806.1 - 1.2e-06 29.0 0.2 2.5e-06 28.0 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain Amidase02_C PF12123.8 EAX89807.1 - 0.0056 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX89808.1 - 1.4e-65 220.4 13.4 1.6e-63 213.7 13.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX89808.1 - 0.091 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DOCK-C2 PF14429.6 EAX89809.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Epimerase PF01370.21 EAX89810.1 - 3e-40 138.2 0.0 4.8e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAX89810.1 - 7.4e-25 88.0 0.0 4e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAX89810.1 - 1.2e-11 44.2 0.0 1.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EAX89810.1 - 2.4e-06 27.6 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAX89810.1 - 0.00058 19.5 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EAX89810.1 - 0.026 13.7 0.0 1.6 7.8 0.0 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF829 PF05705.14 EAX89811.1 - 1.8e-50 172.1 0.1 2e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 EAX89811.1 - 5.5e-07 29.3 0.1 8.3e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family HopW1-1 PF15457.6 EAX89811.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Gly_rich PF12810.7 EAX89813.1 - 1.6e-08 34.8 16.9 2.1e-08 34.4 16.9 1.2 1 0 0 1 1 1 1 Glycine rich protein DUF4611 PF15387.6 EAX89814.1 - 6.3 7.1 15.1 0.14 12.4 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Adeno_E3_CR2 PF02439.15 EAX89815.1 - 2.2e-05 24.1 5.6 5.2e-05 22.9 5.6 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 EAX89815.1 - 0.0041 17.2 1.9 0.01 15.9 1.9 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment CD99L2 PF12301.8 EAX89815.1 - 0.019 15.3 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Vpu PF00558.19 EAX89815.1 - 0.025 14.3 0.3 0.05 13.4 0.3 1.4 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.6 EAX89815.1 - 0.092 13.6 0.1 0.31 11.9 0.2 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 EAX89815.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PTR PF12789.7 EAX89816.1 - 5.4e-51 170.5 29.2 4.3e-34 116.4 16.5 4.1 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX89816.1 - 0.043 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX89816.1 - 0.47 10.8 3.6 26 5.2 0.1 3.2 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF1524 PF07510.11 EAX89816.1 - 4.9 7.0 15.4 0.84 9.5 2.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1524) T5orf172 PF10544.9 EAX89817.1 - 1.5e-06 28.7 0.0 3.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX89817.1 - 0.018 14.9 1.8 0.069 13.0 0.7 2.4 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX89817.1 - 0.093 12.3 0.6 0.24 10.9 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX89818.1 - 2.6e-33 114.2 0.6 5.7e-33 113.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX89818.1 - 0.022 15.4 0.0 0.06 14.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX89819.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX89819.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX89819.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX89819.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX89819.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX89819.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX89819.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX89821.1 - 6.7e-64 214.1 6.3 7.4e-64 214.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX89822.1 - 1.9e-05 25.0 3.0 0.00012 22.5 3.0 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX89822.1 - 0.08 13.6 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Myb_DNA-binding PF00249.31 EAX89823.1 - 1.6e-25 89.0 3.7 6.3e-15 55.1 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89823.1 - 1.2e-24 86.3 5.9 2.5e-14 53.2 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89823.1 - 7.8e-08 32.3 1.4 0.0014 18.6 0.0 3.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX89823.1 - 0.00027 21.2 1.4 0.0075 16.6 0.1 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EAX89823.1 - 0.0036 17.4 0.6 0.61 10.2 0.3 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EAX89823.1 - 0.018 14.9 0.8 0.061 13.2 0.1 2.1 2 1 0 2 2 2 0 Myb DNA-binding like FCH PF00611.23 EAX89823.1 - 0.029 14.7 0.2 0.35 11.2 0.1 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Myb_DNA-bind_2 PF08914.11 EAX89823.1 - 0.03 14.5 0.0 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Rap1 Myb domain Nore1-SARAH PF16517.5 EAX89823.1 - 0.048 13.6 1.9 3.6 7.6 0.2 3.1 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain SANT_DAMP1_like PF16282.5 EAX89823.1 - 0.055 13.7 0.4 0.18 12.0 0.2 2.0 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3336 PF11815.8 EAX89824.1 - 0.0047 16.7 0.7 1.7 8.4 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Gly_rich PF12810.7 EAX89826.1 - 1.7e-35 123.1 22.6 2.1e-35 122.8 22.6 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX89827.1 - 5.4e-21 75.6 28.8 6.2e-21 75.4 28.8 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX89828.1 - 4.1e-93 308.0 55.1 7.7e-26 90.6 7.3 5.1 3 1 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89828.1 - 8.3e-17 60.7 0.0 0.0035 17.1 0.0 8.0 5 4 3 8 8 8 5 Leucine rich repeat Fer4_20 PF14691.6 EAX89829.1 - 0.00028 20.6 0.8 0.00054 19.7 0.1 1.7 1 1 1 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DHO_dh PF01180.21 EAX89830.1 - 7.3e-32 110.8 0.0 1.4e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Pyr_redox_2 PF07992.14 EAX89830.1 - 4.9e-23 81.8 0.1 9.1e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 EAX89830.1 - 5.5e-17 61.6 11.1 5.5e-17 61.6 11.1 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 EAX89830.1 - 5.8e-11 42.8 0.3 0.0001 22.8 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAX89830.1 - 1.1e-10 41.3 0.1 0.00038 19.8 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAX89830.1 - 4.6e-09 36.4 0.1 1.1e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fer4 PF00037.27 EAX89830.1 - 1.3e-06 28.0 15.0 5.6e-06 25.9 1.3 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EAX89830.1 - 3.6e-06 27.5 21.1 0.0001 22.8 11.1 2.8 2 1 2 4 4 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAX89830.1 - 6.6e-06 26.2 12.2 0.00049 20.2 12.8 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain FAD_oxidored PF12831.7 EAX89830.1 - 1.5e-05 24.5 0.4 9.2e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAX89830.1 - 3e-05 23.4 0.0 0.0002 20.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EAX89830.1 - 6.9e-05 22.6 1.2 0.00084 19.0 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Fer4_6 PF12837.7 EAX89830.1 - 0.00011 22.2 17.9 0.01 15.9 3.0 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 EAX89830.1 - 0.00027 21.0 9.5 0.00027 21.0 9.5 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain PALP PF00291.25 EAX89830.1 - 0.00049 19.6 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Fer4_4 PF12800.7 EAX89830.1 - 0.00071 19.9 13.3 0.032 14.7 2.8 3.2 2 0 0 2 2 2 2 4Fe-4S binding domain AlaDh_PNT_C PF01262.21 EAX89830.1 - 0.00087 18.6 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EAX89830.1 - 0.001 18.4 0.0 0.23 10.8 0.0 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_16 PF13484.6 EAX89830.1 - 0.0012 19.7 12.1 0.012 16.5 1.1 3.4 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain HI0933_like PF03486.14 EAX89830.1 - 0.0014 17.4 1.2 0.012 14.3 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EAX89830.1 - 0.0018 17.6 0.4 0.018 14.3 0.1 2.5 3 0 0 3 3 3 1 Thi4 family Fer4_20 PF14691.6 EAX89830.1 - 0.0022 17.8 0.0 0.0022 17.8 0.0 3.8 3 1 1 4 4 3 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_22 PF17179.4 EAX89830.1 - 0.0023 18.8 2.8 1 10.2 0.3 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain NAD_binding_7 PF13241.6 EAX89830.1 - 0.0062 17.0 0.0 0.63 10.5 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding FMO-like PF00743.19 EAX89830.1 - 0.0071 14.8 0.1 0.22 9.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 EAX89830.1 - 0.009 15.1 1.1 0.022 13.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EAX89830.1 - 0.0097 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 EAX89830.1 - 0.011 14.8 0.5 0.45 9.5 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Fer4_2 PF12797.7 EAX89830.1 - 0.012 15.7 18.0 0.056 13.6 1.8 3.4 3 0 0 3 3 2 0 4Fe-4S binding domain XdhC_C PF13478.6 EAX89830.1 - 0.016 15.7 0.0 8.5 6.9 0.0 2.9 3 0 0 3 3 2 0 XdhC Rossmann domain IlvN PF07991.12 EAX89830.1 - 0.023 14.3 0.1 2.7 7.5 0.0 2.9 3 0 0 3 3 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 EAX89830.1 - 0.066 13.2 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Oxidored_nitro PF00148.19 EAX89830.1 - 0.096 11.4 0.0 8.7 5.0 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.21 EAX89830.1 - 0.12 12.4 7.2 1.2 9.2 0.1 3.4 4 0 0 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fer4_8 PF13183.6 EAX89830.1 - 0.46 11.0 13.6 0.69 10.4 3.3 2.8 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 EAX89830.1 - 0.83 10.2 13.5 3.2 8.4 2.9 2.9 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EAX89830.1 - 0.85 10.2 13.9 0.22 12.1 2.8 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EAX89830.1 - 2.5 8.9 9.3 1.2 10.0 1.0 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 EAX89830.1 - 5.5 8.2 20.4 2.6 9.2 6.4 3.6 3 0 0 3 3 2 0 4Fe-4S binding domain Prenyltrans PF00432.21 EAX89831.1 - 6.9e-32 108.9 2.3 2.2e-12 46.5 0.1 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EAX89831.1 - 0.00011 21.4 0.0 0.00089 18.4 0.0 2.0 2 0 0 2 2 2 1 Squalene-hopene cyclase N-terminal domain Ras PF00071.22 EAX89832.1 - 3.1e-34 117.9 0.0 3.5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89832.1 - 1.3e-28 99.7 0.0 1.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89832.1 - 8.6e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX89832.1 - 4.1e-06 26.3 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX89832.1 - 3.1e-05 24.0 0.1 4.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX89832.1 - 0.00021 20.8 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX89832.1 - 0.0018 18.7 0.9 0.01 16.2 0.9 1.9 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EAX89832.1 - 0.0024 17.5 0.3 0.02 14.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX89832.1 - 0.0025 17.7 0.5 0.051 13.5 0.2 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EAX89832.1 - 0.0079 16.5 0.5 0.14 12.5 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX89832.1 - 0.0089 16.4 0.0 0.024 15.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAX89832.1 - 0.031 14.0 0.1 0.067 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EAX89832.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EAX89832.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 EAX89832.1 - 0.11 11.6 0.1 4 6.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EAX89832.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EAX89832.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) EAF PF09816.9 EAX89833.1 - 6.3e-06 26.5 0.1 7.4e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor MULE PF10551.9 EAX89834.1 - 2.9e-10 40.4 0.2 7.5e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX89834.1 - 0.0067 15.3 0.2 0.013 14.4 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX89834.1 - 0.0085 15.8 0.4 0.043 13.5 0.3 1.9 1 1 1 2 2 2 1 Transposase FAR1 PF03101.15 EAX89834.1 - 0.072 13.8 0.1 0.16 12.7 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Vta1 PF04652.16 EAX89834.1 - 0.094 12.7 1.2 0.14 12.1 0.3 1.7 2 0 0 2 2 2 0 Vta1 like PTR PF12789.7 EAX89836.1 - 3.3e-12 46.3 29.3 1e-07 31.9 5.0 4.9 4 1 0 4 4 4 3 Phage tail repeat like DUF4795 PF16043.5 EAX89836.1 - 4.6 6.8 11.4 3 7.4 0.4 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4795) T5orf172 PF10544.9 EAX89837.1 - 1.3e-06 28.9 0.2 2.6e-06 27.9 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain FAS_N PF17828.1 EAX89838.1 - 0.027 14.5 0.1 0.039 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX89839.1 - 0.068 13.1 10.0 0.11 12.5 10.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-binding PF00249.31 EAX89842.1 - 3.2e-29 100.9 0.8 5.9e-15 55.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89842.1 - 1.4e-24 86.1 2.1 3.5e-17 62.4 1.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX89842.1 - 0.0012 19.0 1.3 4.2 7.6 0.4 3.4 2 1 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EAX89842.1 - 0.01 15.9 3.9 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_7 PF15963.5 EAX89842.1 - 0.015 15.2 9.7 0.15 11.9 0.0 3.7 3 1 2 5 5 5 0 Myb DNA-binding like Atg29_N PF18388.1 EAX89842.1 - 0.05 13.4 1.0 0.086 12.7 0.1 1.8 2 0 0 2 2 2 0 Atg29 N-terminal domain NuiA PF07924.11 EAX89842.1 - 0.2 12.1 1.1 0.32 11.4 0.1 1.8 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Myb_DNA-bind_5 PF13873.6 EAX89842.1 - 2.7 8.1 6.6 16 5.7 0.7 3.6 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Fibrinogen_aC PF12160.8 EAX89843.1 - 3.4 7.6 10.2 13 5.7 0.1 4.7 4 0 0 4 4 4 0 Fibrinogen alpha C domain Peptidase_M8 PF01457.16 EAX89844.1 - 9.3e-05 21.3 0.0 0.00011 21.1 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF3447 PF11929.8 EAX89846.1 - 6.8e-07 29.2 2.9 6.8e-07 29.2 2.9 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89846.1 - 3.3e-05 24.4 0.2 0.36 11.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89846.1 - 0.034 14.8 0.1 17 6.2 0.0 3.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Sec8_exocyst PF04048.14 EAX89846.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ank PF00023.30 EAX89846.1 - 0.19 12.3 0.0 33 5.1 0.0 3.3 2 1 0 2 2 2 0 Ankyrin repeat PRA-PH PF01503.17 EAX89847.1 - 0.34 11.4 2.8 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4116 PF13475.6 EAX89848.1 - 0.0047 16.6 1.0 0.0082 15.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) TMP PF05017.14 EAX89850.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89851.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-binding PF00249.31 EAX89852.1 - 3.4e-32 110.4 0.8 1.3e-17 63.7 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89852.1 - 2.1e-25 88.7 1.5 3.6e-18 65.6 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX89852.1 - 9.3e-06 25.5 0.0 0.016 15.1 0.0 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX89852.1 - 0.0036 17.3 0.0 0.079 13.0 0.0 2.6 1 1 1 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 EAX89852.1 - 0.012 15.8 0.0 1.3 9.3 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 IRF PF00605.17 EAX89852.1 - 0.026 14.8 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Atg29_N PF18388.1 EAX89852.1 - 0.96 9.3 5.9 2.2 8.1 0.1 2.9 4 0 0 4 4 4 0 Atg29 N-terminal domain DUF1477 PF07346.11 EAX89856.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) DUF3746 PF12562.8 EAX89856.1 - 0.35 10.8 2.0 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) rve PF00665.26 EAX89857.1 - 1.5e-13 50.9 0.0 2.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX89857.1 - 1e-06 29.1 0.1 2.3e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.6 EAX89857.1 - 0.0056 16.4 0.5 0.25 11.1 0.1 2.6 2 0 0 2 2 2 1 Integrase core domain MULE PF10551.9 EAX89859.1 - 1.7e-10 41.2 1.2 3e-10 40.4 1.2 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX89859.1 - 0.00083 19.4 1.1 0.0028 17.7 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Fe-ADH PF00465.19 EAX89861.1 - 6.5e-21 74.6 0.0 7.7e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase BppL_N PF18338.1 EAX89861.1 - 0.094 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain zf-MIZ PF02891.20 EAX89863.1 - 0.091 12.5 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Pkinase_Tyr PF07714.17 EAX89864.1 - 4.6e-26 91.6 0.0 1e-24 87.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX89864.1 - 1.6e-17 63.8 0.0 2.8e-16 59.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain DUF3677 PF12432.8 EAX89864.1 - 0.48 10.8 4.9 14 6.1 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3677) RUN PF02759.19 EAX89865.1 - 0.01 15.8 0.9 2.3 8.1 0.7 3.1 2 0 0 2 2 2 0 RUN domain Metallophos PF00149.28 EAX89866.1 - 6.9e-37 127.9 0.0 9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX89866.1 - 2.5e-08 34.2 0.6 5.1e-08 33.2 0.6 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX89866.1 - 0.00032 20.9 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L6e PF01159.19 EAX89868.1 - 5.6e-10 39.7 0.2 6.5e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e Metallophos PF00149.28 EAX89870.1 - 6.9e-30 105.1 2.0 1.3e-29 104.2 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX89870.1 - 0.0015 18.7 0.0 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF771 PF05595.11 EAX89870.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF771) AMP-binding PF00501.28 EAX89871.1 - 6.7e-99 331.3 0.0 9.4e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAX89871.1 - 0.003 18.5 0.1 0.0069 17.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Adaptin_N PF01602.20 EAX89873.1 - 6.6e-70 236.1 15.4 8.5e-70 235.8 15.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EAX89873.1 - 2e-16 60.2 2.0 5.5e-16 58.8 2.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 EAX89873.1 - 7.3e-05 22.7 0.1 4.7 7.7 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EAX89873.1 - 0.00053 20.1 7.9 1.8 8.6 0.0 5.1 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 hSH3 PF14603.6 EAX89873.1 - 0.071 13.5 0.1 0.24 11.8 0.1 1.9 1 0 0 1 1 1 0 Helically-extended SH3 domain NPCBM_assoc PF10633.9 EAX89873.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase V-ATPase_H_C PF11698.8 EAX89873.1 - 0.68 10.1 5.3 1 9.5 0.0 3.9 4 2 1 5 5 5 0 V-ATPase subunit H Cyclin_N PF00134.23 EAX89874.1 - 1.3e-07 31.4 1.2 4.1e-06 26.6 0.2 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain DHR-2 PF06920.13 EAX89875.1 - 3.8e-107 359.1 9.7 6.1e-107 358.4 9.7 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EAX89875.1 - 3.6e-07 30.2 0.1 9.8e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins PSP PF04046.16 EAX89876.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89877.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX89878.1 - 3.3e-63 209.6 40.7 1.6e-34 117.8 14.3 5.3 2 2 2 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX89878.1 - 0.034 13.9 0.9 0.061 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) CLASP_N PF12348.8 EAX89879.1 - 2.9e-22 79.3 7.6 6.7e-20 71.6 2.7 3.0 2 1 0 2 2 2 2 CLASP N terminal DDE_Tnp_ISL3 PF01610.17 EAX89879.1 - 0.015 15.1 1.7 4.9 6.8 0.1 2.6 2 0 0 2 2 2 0 Transposase Peptidase_M16_C PF05193.21 EAX89879.1 - 0.22 11.5 3.5 0.5 10.4 0.1 2.7 2 1 0 2 2 2 0 Peptidase M16 inactive domain AAA PF00004.29 EAX89879.1 - 0.29 11.6 3.6 3.6 8.0 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF4407 PF14362.6 EAX89879.1 - 5.1 6.4 12.0 0.22 10.9 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3796 PF12676.7 EAX89880.1 - 0.016 15.7 0.4 0.037 14.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Pik1 PF11522.8 EAX89881.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.5 4 0 0 4 4 4 0 Yeast phosphatidylinositol-4-OH kinase Pik1 TMEM107 PF14995.6 EAX89882.1 - 7.3e-35 120.1 8.4 9.8e-35 119.7 8.4 1.2 1 0 0 1 1 1 1 Transmembrane protein DUF2207 PF09972.9 EAX89882.1 - 0.23 10.2 3.7 0.28 9.9 3.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CAAD PF14159.6 EAX89882.1 - 0.31 10.9 6.4 0.4 10.5 5.1 1.9 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase TMEM100 PF16311.5 EAX89882.1 - 1.8 8.2 3.3 1.5 8.4 0.9 1.9 2 0 0 2 2 2 0 Transmembrane protein 100 SRP40_C PF05022.12 EAX89885.1 - 2.8e-06 28.1 1.7 8.8e-06 26.5 1.7 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain UCH PF00443.29 EAX89887.1 - 1.1e-25 90.6 1.0 2.2e-25 89.6 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VraX PF17412.2 EAX89887.1 - 0.79 9.4 3.2 1.9 8.2 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function Gly-zipper_Omp PF13488.6 EAX89888.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX89888.1 - 0.24 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX89888.1 - 0.85 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif HlyIII PF03006.20 EAX89890.1 - 9.2e-23 81.1 9.8 1.1e-22 80.8 9.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related MerC PF03203.14 EAX89890.1 - 0.007 16.8 2.1 0.0089 16.5 0.9 1.7 1 1 1 2 2 2 1 MerC mercury resistance protein U-box PF04564.15 EAX89891.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF2155 PF09923.9 EAX89891.1 - 0.037 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) Myb_DNA-bind_4 PF13837.6 EAX89891.1 - 0.049 14.0 1.9 0.96 9.9 0.4 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RIX1 PF08167.12 EAX89894.1 - 0.00037 20.3 10.2 0.46 10.2 0.0 5.9 5 1 2 7 7 7 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EAX89894.1 - 0.0031 18.1 2.5 2.5 8.7 0.0 4.9 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region MIF4G PF02854.19 EAX89894.1 - 0.0034 17.0 0.3 0.0034 17.0 0.3 4.1 5 0 0 5 5 5 1 MIF4G domain Cnd1 PF12717.7 EAX89894.1 - 0.026 14.5 18.1 0.028 14.5 0.3 4.8 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EAX89894.1 - 0.031 13.4 8.8 1 8.4 0.4 4.1 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Mod_r PF07200.13 EAX89894.1 - 0.031 14.4 7.9 0.25 11.4 0.0 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein NUC173 PF08161.12 EAX89894.1 - 0.068 12.8 3.0 0.57 9.8 0.0 3.9 4 0 0 4 4 4 0 NUC173 domain HEAT PF02985.22 EAX89894.1 - 0.088 13.1 3.0 24 5.5 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat SPG48 PF14764.6 EAX89894.1 - 0.85 10.1 10.7 0.34 11.4 0.1 5.2 5 2 0 5 5 5 0 AP-5 complex subunit, vesicle trafficking Telomere_reg-2 PF10193.9 EAX89894.1 - 5.6 7.5 0.0 5.6 7.5 0.0 6.1 4 2 3 7 7 7 0 Telomere length regulation protein zf-ANAPC11 PF12861.7 EAX89895.1 - 0.14 12.2 4.0 0.18 11.9 0.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Gly-zipper_Omp PF13488.6 EAX89899.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX89899.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX89899.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4833 PF16117.5 EAX89900.1 - 2.4e-14 53.5 0.2 2.7e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) DUF1292 PF06949.11 EAX89900.1 - 0.025 15.5 0.2 0.025 15.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) Y_phosphatase3 PF13350.6 EAX89901.1 - 9.7e-58 195.9 0.0 1.1e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EAX89901.1 - 0.00025 20.9 0.1 0.00049 19.9 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EAX89901.1 - 0.00079 19.0 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PET10 PF17316.2 EAX89901.1 - 0.023 14.2 0.1 0.023 14.2 0.1 1.5 2 0 0 2 2 2 0 Petite colonies protein 10 Y_phosphatase PF00102.27 EAX89901.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.14 EAX89901.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ras PF00071.22 EAX89902.1 - 1.2e-45 155.1 0.1 1.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89902.1 - 4e-31 107.7 0.0 5.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89902.1 - 2.6e-17 62.8 0.0 3.4e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX89902.1 - 6.1e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX89902.1 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX89902.1 - 0.00023 20.6 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 EAX89902.1 - 0.012 15.9 0.2 0.042 14.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 EAX89902.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 EAX89902.1 - 0.016 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein adh_short_C2 PF13561.6 EAX89902.1 - 0.097 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Arf PF00025.21 EAX89903.1 - 2e-25 89.3 0.0 2.3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX89903.1 - 7e-08 32.7 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAX89903.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX89903.1 - 0.00048 19.4 0.8 0.057 12.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EAX89903.1 - 0.0007 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EAX89903.1 - 0.011 15.5 0.0 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2478 PF10649.9 EAX89903.1 - 0.023 14.3 0.0 0.31 10.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2478) DCX PF03607.17 EAX89903.1 - 0.028 14.5 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Doublecortin WD40 PF00400.32 EAX89904.1 - 4.6e-05 24.1 2.8 9.9 7.2 0.1 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX89904.1 - 0.00013 22.1 0.0 4.7 7.6 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EAX89904.1 - 0.0066 16.9 0.1 35 5.1 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 EAX89904.1 - 0.05 13.6 0.0 3.8 7.6 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat Rootletin PF15035.6 EAX89904.1 - 0.06 13.4 16.6 0.1 12.6 16.4 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 EAX89904.1 - 0.12 11.2 22.2 0.12 11.2 5.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 EAX89904.1 - 0.13 12.3 25.3 0.18 11.9 4.4 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EAX89904.1 - 0.52 10.4 15.5 2.1 8.4 1.5 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 EAX89904.1 - 1.1 8.9 27.6 0.41 10.4 7.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3552 PF12072.8 EAX89904.1 - 5.7 6.3 14.9 2.1 7.7 9.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CC2-LZ PF16516.5 EAX89904.1 - 7.4 7.0 20.3 5.6 7.4 3.5 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 EAX89904.1 - 7.4 5.5 20.2 5.3 6.0 7.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 EAX89904.1 - 8.9 6.6 16.6 2.4 8.4 0.7 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein Toxin_R_bind_C PF07951.12 EAX89905.1 - 0.046 13.4 1.5 0.046 13.4 0.4 1.5 2 0 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding YfbU PF03887.14 EAX89905.1 - 0.078 13.0 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 YfbU domain Antimicrobial_8 PF08103.11 EAX89905.1 - 7.2 7.0 6.3 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 Uperin family Herpes_IE2_3 PF03361.14 EAX89906.1 - 0.0051 16.7 1.2 0.29 11.0 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX89906.1 - 0.011 16.0 4.4 1.4 9.3 1.3 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region YlbD_coat PF14071.6 EAX89906.1 - 0.074 13.3 1.8 2.4 8.5 0.4 2.1 2 0 0 2 2 2 0 Putative coat protein zf-RNPHF PF08080.12 EAX89907.1 - 0.07 13.1 14.8 1.3e+02 2.6 0.0 11.0 12 1 1 13 13 13 0 RNPHF zinc finger EAR PF07897.11 EAX89907.1 - 0.19 11.4 3.9 97 2.7 0.1 4.9 3 0 0 3 3 3 0 Ethylene-responsive binding factor-associated repression HHH PF00633.23 EAX89907.1 - 0.63 10.0 14.4 1.1e+02 2.9 0.0 8.8 11 1 1 12 12 12 0 Helix-hairpin-helix motif Clathrin-link PF09268.10 EAX89907.1 - 3.2 7.2 9.3 2.2e+02 1.3 0.1 5.8 5 0 0 5 5 5 0 Clathrin, heavy-chain linker DUF4090 PF13319.6 EAX89908.1 - 1.8e-06 28.1 4.1 69 3.8 0.0 8.9 6 2 1 8 8 8 1 Protein of unknown function (DUF4090) Keratin_B2 PF01500.17 EAX89908.1 - 0.0065 16.5 78.4 0.63 10.0 9.5 6.8 1 1 6 7 7 7 7 Keratin, high sulfur B2 protein MetallophosC PF16370.5 EAX89909.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase AA_permease PF00324.21 EAX89910.1 - 5.4e-32 111.0 38.2 8.2e-32 110.4 38.2 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EAX89910.1 - 4.5e-28 98.4 0.2 1.1e-21 77.4 0.1 3.2 1 1 1 2 2 2 2 Solute carrier family 12 DEAD PF00270.29 EAX89911.1 - 3.3e-41 141.0 1.1 8.2e-41 139.7 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX89911.1 - 3e-24 85.5 0.1 2.2e-22 79.5 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAX89911.1 - 1.2e-11 44.7 0.0 4.7e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAX89911.1 - 1.8e-07 31.3 0.3 1.8e-07 31.3 0.3 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EAX89911.1 - 0.00017 20.4 0.0 0.0003 19.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.14 EAX89911.1 - 0.0038 16.6 0.2 0.0038 16.6 0.2 1.9 2 0 0 2 2 2 1 SecA DEAD-like domain AGOG PF09171.10 EAX89911.1 - 0.022 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 N-glycosylase/DNA lyase AAA_22 PF13401.6 EAX89911.1 - 0.056 13.7 1.1 0.31 11.3 1.1 2.3 1 1 0 1 1 1 0 AAA domain MFAP1 PF06991.11 EAX89911.1 - 1.2 9.0 35.2 0.034 14.0 28.1 1.9 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing FAM178 PF14816.6 EAX89911.1 - 8.7 5.2 11.2 22 3.9 11.2 1.7 1 0 0 1 1 1 0 Family of unknown function, FAM178 IFT81_CH PF18383.1 EAX89913.1 - 1.7e-19 70.2 0.3 1.7e-19 70.2 0.3 3.4 5 0 0 5 5 5 1 Intraflagellar transport 81 calponin homology domain Methyltransf_16 PF10294.9 EAX89914.1 - 1.7e-17 63.7 0.0 2.1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EAX89914.1 - 1.4e-06 28.9 0.0 3.2e-06 27.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX89914.1 - 4.6e-05 23.3 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX89914.1 - 9.9e-05 23.0 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX89914.1 - 0.00013 21.8 0.0 0.0015 18.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EAX89914.1 - 0.00018 21.0 0.1 0.00022 20.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EAX89914.1 - 0.00019 22.0 0.0 0.00034 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EAX89914.1 - 0.00022 21.2 0.0 0.00056 19.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Cons_hypoth95 PF03602.15 EAX89914.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EAX89914.1 - 0.0097 15.5 0.1 0.022 14.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EAX89914.1 - 0.098 12.4 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Hydrolase_3 PF08282.12 EAX89915.1 - 1.6 8.4 8.0 0.17 11.6 2.4 2.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HSP70 PF00012.20 EAX89916.1 - 1.6e-48 165.3 9.2 1.6e-48 165.3 9.2 2.0 1 1 1 2 2 2 1 Hsp70 protein RolB_RolC PF02027.17 EAX89916.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 RolB/RolC glucosidase family FtsA PF14450.6 EAX89916.1 - 0.051 14.0 1.4 0.49 10.8 0.1 3.0 2 1 0 2 2 2 0 Cell division protein FtsA Maelstrom PF13017.6 EAX89916.1 - 0.063 12.9 4.3 2.9 7.5 0.7 2.6 2 0 0 2 2 2 0 piRNA pathway germ-plasm component ART-PolyVal PF18760.1 EAX89916.1 - 0.11 13.5 1.5 0.3 12.1 0.3 2.2 1 1 1 2 2 2 0 ADP-Ribosyltransferase in polyvalent proteins His_Phos_2 PF00328.22 EAX89916.1 - 0.76 9.1 8.8 0.086 12.2 0.3 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) F5_F8_type_C PF00754.25 EAX89917.1 - 0.042 14.0 0.5 0.077 13.1 0.5 1.4 1 0 0 1 1 1 0 F5/8 type C domain Ank_2 PF12796.7 EAX89919.1 - 7e-37 125.9 1.9 7.7e-18 64.9 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89919.1 - 3e-31 107.4 0.1 1.3e-09 38.4 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89919.1 - 8.5e-28 96.1 1.0 3.1e-09 36.9 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89919.1 - 6e-24 81.5 0.2 0.00065 20.0 0.0 7.0 7 0 0 7 7 6 5 Ankyrin repeat Ank PF00023.30 EAX89919.1 - 4.8e-19 67.9 0.0 0.00043 20.6 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Fez1 PF06818.15 EAX89919.1 - 0.00077 20.0 1.5 0.00077 20.0 1.5 1.4 2 0 0 2 2 1 1 Fez1 CENP-F_leu_zip PF10473.9 EAX89919.1 - 0.0008 19.5 4.8 0.0014 18.6 4.8 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EAX89919.1 - 0.0013 19.3 5.8 0.0028 18.2 5.8 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 EAX89919.1 - 0.0014 18.9 3.2 0.0022 18.3 3.2 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3287 PF11690.8 EAX89919.1 - 0.032 13.9 0.3 0.071 12.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF3450 PF11932.8 EAX89919.1 - 0.057 12.7 3.8 0.096 12.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 EAX89919.1 - 0.075 13.1 6.7 0.18 11.8 6.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.6 EAX89919.1 - 0.084 13.0 0.7 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.9 EAX89919.1 - 0.11 12.7 4.4 0.24 11.6 4.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 zf-C4H2 PF10146.9 EAX89919.1 - 0.13 12.5 6.7 0.034 14.5 3.7 1.5 2 0 0 2 2 1 0 Zinc finger-containing protein DUF724 PF05266.14 EAX89919.1 - 0.16 11.8 4.8 0.33 10.7 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 EAX89919.1 - 0.18 12.5 7.2 0.78 10.4 7.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA LPP PF04728.13 EAX89919.1 - 0.19 12.1 8.3 4.3 7.8 0.1 2.9 3 0 0 3 3 2 0 Lipoprotein leucine-zipper LOH1CR12 PF10158.9 EAX89919.1 - 0.22 11.6 5.9 0.4 10.7 5.9 1.4 1 0 0 1 1 1 0 Tumour suppressor protein ADIP PF11559.8 EAX89919.1 - 0.23 11.6 14.0 0.094 12.8 10.1 2.2 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 EAX89919.1 - 0.25 11.4 17.1 0.31 11.2 1.2 3.0 2 1 1 3 3 2 0 bZIP transcription factor DASH_Spc19 PF08287.11 EAX89919.1 - 0.33 10.8 5.7 0.72 9.7 5.7 1.5 1 0 0 1 1 1 0 Spc19 ABC_tran_CTD PF16326.5 EAX89919.1 - 0.39 11.0 4.1 0.91 9.8 4.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMF_TATA_bd PF12325.8 EAX89919.1 - 0.43 10.8 9.0 0.22 11.8 6.1 2.0 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding DUF4472 PF14739.6 EAX89919.1 - 0.6 10.9 9.7 1.3 9.8 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Fungal_TACC PF12709.7 EAX89919.1 - 0.76 10.3 12.8 4.9 7.7 1.7 3.4 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins BRE1 PF08647.11 EAX89919.1 - 1.1 9.4 18.8 0.06 13.4 12.0 2.3 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 EAX89919.1 - 2.2 8.4 13.8 0.11 12.5 7.2 2.3 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 EAX89919.1 - 3.8 8.0 6.1 20 5.6 6.1 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 EAX89919.1 - 4.1 7.9 13.8 0.17 12.3 5.8 2.5 2 1 1 3 3 2 0 Cell division protein ZapB TSC22 PF01166.18 EAX89919.1 - 4.5 7.7 12.7 1.2 9.5 2.1 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family GIT_CC PF16559.5 EAX89919.1 - 4.8 7.1 8.0 6.6 6.7 1.5 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2935 PF11155.8 EAX89919.1 - 8.4 6.8 9.6 2.5 8.5 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Ank_2 PF12796.7 EAX89920.1 - 1.6e-47 160.0 7.5 7.8e-19 68.1 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89920.1 - 3.1e-34 116.9 0.1 3.3e-08 33.9 0.0 4.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89920.1 - 3.6e-30 103.6 2.8 2.9e-09 37.0 0.0 5.7 1 1 5 6 6 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89920.1 - 7.2e-25 84.4 0.2 0.00061 20.0 0.0 7.3 8 0 0 8 8 6 4 Ankyrin repeat Ank PF00023.30 EAX89920.1 - 2.1e-23 81.7 0.0 0.00041 20.7 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat ATG16 PF08614.11 EAX89920.1 - 4.2e-05 23.9 6.8 7.7e-05 23.0 6.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EAX89920.1 - 0.00011 22.7 6.6 0.00011 22.7 6.6 1.5 2 0 0 2 2 1 1 Fez1 MAD PF05557.13 EAX89920.1 - 0.00012 20.6 5.4 0.00018 20.0 5.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein GAS PF13851.6 EAX89920.1 - 0.00019 20.8 11.4 0.00043 19.7 11.4 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EAX89920.1 - 0.00024 20.1 10.6 0.00047 19.1 10.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein GIT_CC PF16559.5 EAX89920.1 - 0.00027 20.7 6.9 0.00061 19.6 3.7 2.6 1 1 1 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 EAX89920.1 - 0.00033 20.9 14.4 0.014 15.7 1.2 3.3 2 1 1 3 3 2 2 TSC-22/dip/bun family EzrA PF06160.12 EAX89920.1 - 0.00034 18.9 14.8 0.00034 18.9 14.8 1.6 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA BRE1 PF08647.11 EAX89920.1 - 0.00048 20.1 14.7 0.00048 20.1 14.7 2.3 3 0 0 3 3 1 1 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 EAX89920.1 - 0.00059 20.1 8.3 0.0012 19.0 8.3 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DivIC PF04977.15 EAX89920.1 - 0.0007 19.3 13.8 0.22 11.3 4.7 2.9 1 1 1 2 2 2 2 Septum formation initiator DUF1664 PF07889.12 EAX89920.1 - 0.00078 19.5 6.2 0.0016 18.5 6.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ADIP PF11559.8 EAX89920.1 - 0.00086 19.4 13.6 0.00086 19.4 13.6 2.3 2 1 1 3 3 2 2 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EAX89920.1 - 0.00091 19.8 10.5 0.00091 19.8 10.5 2.2 1 1 1 2 2 1 1 Apg6 coiled-coil region Filament PF00038.21 EAX89920.1 - 0.0011 18.6 7.9 0.0023 17.6 7.9 1.5 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 EAX89920.1 - 0.0014 18.1 6.5 0.0023 17.5 6.5 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF812 PF05667.11 EAX89920.1 - 0.0016 17.4 9.7 0.0054 15.7 9.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF724 PF05266.14 EAX89920.1 - 0.0017 18.2 10.4 0.0018 18.1 9.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF724) HemX PF04375.14 EAX89920.1 - 0.002 17.4 3.2 0.002 17.4 3.2 1.4 1 1 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 EAX89920.1 - 0.003 17.7 8.5 0.0054 16.9 8.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus LPP PF04728.13 EAX89920.1 - 0.0031 17.9 3.7 0.0031 17.9 3.7 2.9 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Atg14 PF10186.9 EAX89920.1 - 0.0039 16.3 13.2 0.0061 15.7 13.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS5 PF14817.6 EAX89920.1 - 0.0042 15.9 6.0 0.0059 15.4 6.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 zf-C4H2 PF10146.9 EAX89920.1 - 0.005 17.2 7.8 0.005 17.2 7.8 1.7 2 0 0 2 2 1 1 Zinc finger-containing protein HMMR_N PF15905.5 EAX89920.1 - 0.0059 16.1 10.6 0.01 15.3 10.6 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 EAX89920.1 - 0.006 16.7 11.2 0.0091 16.1 9.3 2.1 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF641 PF04859.12 EAX89920.1 - 0.0063 16.9 7.3 0.0064 16.8 5.9 1.7 2 0 0 2 2 1 1 Plant protein of unknown function (DUF641) DUF5082 PF16888.5 EAX89920.1 - 0.0072 16.6 18.0 0.02 15.2 10.3 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) T3SSipB PF16535.5 EAX89920.1 - 0.0085 16.6 4.4 0.015 15.7 4.4 1.4 1 0 0 1 1 1 1 Type III cell invasion protein SipB THOC7 PF05615.13 EAX89920.1 - 0.01 16.1 8.0 0.027 14.7 8.0 1.7 1 0 0 1 1 1 0 Tho complex subunit 7 Fungal_TACC PF12709.7 EAX89920.1 - 0.012 16.0 14.1 0.34 11.4 2.4 3.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Pox_A_type_inc PF04508.12 EAX89920.1 - 0.012 15.4 2.8 9.7 6.2 0.0 4.3 5 0 0 5 5 3 0 Viral A-type inclusion protein repeat DUF4200 PF13863.6 EAX89920.1 - 0.013 15.9 4.6 0.013 15.9 4.6 3.5 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) OmpH PF03938.14 EAX89920.1 - 0.014 15.8 8.5 0.039 14.3 8.5 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3287 PF11690.8 EAX89920.1 - 0.016 14.9 0.8 0.046 13.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) IFT20 PF14931.6 EAX89920.1 - 0.017 15.3 10.1 0.017 15.3 10.1 2.0 2 0 0 2 2 1 0 Intraflagellar transport complex B, subunit 20 TMPIT PF07851.13 EAX89920.1 - 0.019 14.3 9.5 0.031 13.5 9.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein KASH_CCD PF14662.6 EAX89920.1 - 0.021 14.6 12.9 0.031 14.1 11.6 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 EAX89920.1 - 0.022 14.1 5.5 0.035 13.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 EAX89920.1 - 0.025 13.4 8.9 0.12 11.3 8.9 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 EAX89920.1 - 0.027 13.8 9.7 0.055 12.8 9.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Paramyx_P_V_C PF03210.13 EAX89920.1 - 0.035 13.9 5.5 0.94 9.2 3.6 2.9 2 1 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal FapA PF03961.13 EAX89920.1 - 0.035 12.7 9.9 0.095 11.3 9.9 1.8 1 0 0 1 1 1 0 Flagellar Assembly Protein A Striatin PF08232.12 EAX89920.1 - 0.045 14.3 5.5 0.1 13.2 5.5 1.6 1 0 0 1 1 1 0 Striatin family Exonuc_VII_L PF02601.15 EAX89920.1 - 0.046 13.3 3.8 0.064 12.8 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EAX89920.1 - 0.062 13.5 14.3 0.04 14.1 10.4 2.5 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 EAX89920.1 - 0.065 13.7 3.9 4.2 7.9 1.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) YlqD PF11068.8 EAX89920.1 - 0.073 13.4 7.6 0.15 12.4 7.6 1.5 1 0 0 1 1 1 0 YlqD protein She9_MDM33 PF05546.11 EAX89920.1 - 0.077 12.8 8.4 0.2 11.5 8.4 1.7 1 0 0 1 1 1 0 She9 / Mdm33 family DHR10 PF18595.1 EAX89920.1 - 0.084 12.9 8.3 0.097 12.7 6.1 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 EAX89920.1 - 0.085 13.0 17.2 0.055 13.6 2.1 3.0 2 1 1 3 3 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 EAX89920.1 - 0.087 12.8 13.8 0.019 15.0 10.2 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EAX89920.1 - 0.1 12.8 19.3 0.28 11.4 6.6 2.9 2 1 1 3 3 2 0 Tropomyosin like TBK1_CCD1 PF18394.1 EAX89920.1 - 0.11 12.1 11.8 1.7 8.1 3.0 2.1 1 1 1 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 ABC_tran_CTD PF16326.5 EAX89920.1 - 0.15 12.4 5.8 0.36 11.1 4.9 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Surfac_D-trimer PF09006.11 EAX89920.1 - 0.15 12.0 0.3 11 6.1 0.1 2.6 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation ZapB PF06005.12 EAX89920.1 - 0.16 12.5 19.7 0.39 11.2 3.9 2.8 2 1 1 3 3 2 0 Cell division protein ZapB DUF4472 PF14739.6 EAX89920.1 - 0.18 12.5 12.4 0.07 13.9 9.1 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4472) DUF2203 PF09969.9 EAX89920.1 - 0.19 12.5 4.7 0.44 11.3 4.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CC2-LZ PF16516.5 EAX89920.1 - 0.23 11.9 11.6 0.54 10.7 4.0 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CLZ PF16526.5 EAX89920.1 - 0.25 11.7 3.7 4.2 7.8 0.4 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nnf1 PF03980.14 EAX89920.1 - 0.26 11.7 6.1 0.96 9.9 0.5 2.6 1 1 1 2 2 2 0 Nnf1 DUF848 PF05852.11 EAX89920.1 - 0.3 11.2 5.9 0.32 11.1 3.8 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Uds1 PF15456.6 EAX89920.1 - 0.34 11.1 7.3 3.2 7.9 7.3 2.2 1 1 0 1 1 1 0 Up-regulated During Septation CREPT PF16566.5 EAX89920.1 - 0.35 11.1 7.1 0.64 10.2 0.6 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TolA_bind_tri PF16331.5 EAX89920.1 - 0.36 10.9 5.0 0.52 10.4 2.9 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation HAUS6_N PF14661.6 EAX89920.1 - 0.37 10.3 8.5 1.4 8.5 8.7 1.9 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 6 N-terminus CorA PF01544.18 EAX89920.1 - 0.46 9.7 10.2 0.83 8.9 0.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Ax_dynein_light PF10211.9 EAX89920.1 - 0.57 10.1 15.8 2.3 8.1 3.7 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF489 PF04356.12 EAX89920.1 - 0.63 10.0 5.1 1.2 9.1 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF1640 PF07798.11 EAX89920.1 - 0.76 9.8 11.3 2.4 8.2 11.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YabA PF06156.13 EAX89920.1 - 0.82 10.3 11.4 3.3 8.4 8.7 2.7 1 1 1 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 EAX89920.1 - 0.87 10.2 3.7 19 5.9 0.4 2.4 1 1 1 2 2 2 0 SlyX FlaC_arch PF05377.11 EAX89920.1 - 0.92 10.0 12.7 6.3 7.3 2.3 3.2 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 EAX89920.1 - 1.1 9.5 11.5 4.4 7.5 11.5 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Occludin_ELL PF07303.13 EAX89920.1 - 1.1 10.0 14.4 0.13 13.0 9.2 2.2 2 1 0 2 2 1 0 Occludin homology domain Snapin_Pallidin PF14712.6 EAX89920.1 - 1.6 9.2 9.7 3.5 8.1 8.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin CENP-H PF05837.12 EAX89920.1 - 2.6 8.5 11.9 20 5.7 11.9 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Tup_N PF08581.10 EAX89920.1 - 2.6 8.4 11.4 7.5 6.9 8.9 2.8 1 1 1 2 2 2 0 Tup N-terminal DUF4094 PF13334.6 EAX89920.1 - 2.7 8.5 10.5 0.52 10.7 1.6 3.7 4 1 1 5 5 2 0 Domain of unknown function (DUF4094) Cep57_CLD_2 PF14197.6 EAX89920.1 - 3.1 8.0 7.8 9.4 6.4 2.7 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Complex1_LYR_2 PF13233.6 EAX89920.1 - 3.4 8.5 6.5 14 6.5 4.5 2.9 2 2 1 3 3 1 0 Complex1_LYR-like LMBR1 PF04791.16 EAX89920.1 - 3.9 6.3 7.1 5.4 5.8 7.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EMP24_GP25L PF01105.24 EAX89920.1 - 4.8 7.1 13.4 0.86 9.5 7.2 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.10 EAX89920.1 - 5 7.3 18.1 0.44 10.7 3.6 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_Mu_Gam PF07352.12 EAX89920.1 - 5.1 7.0 16.5 6 6.7 7.5 2.8 2 1 1 3 3 2 0 Bacteriophage Mu Gam like protein FliJ PF02050.16 EAX89920.1 - 6.2 7.1 11.5 0.8 9.9 6.9 2.0 2 0 0 2 2 1 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.22 EAX89920.1 - 6.3 7.1 19.5 0.054 13.7 7.9 2.9 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain P4Ha_N PF08336.11 EAX89920.1 - 6.7 6.7 12.6 4.5 7.3 2.9 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prefoldin PF02996.17 EAX89920.1 - 7.4 6.5 14.5 2.2 8.2 3.0 3.1 2 1 0 3 3 2 0 Prefoldin subunit Fzo_mitofusin PF04799.13 EAX89920.1 - 7.5 6.1 8.8 14 5.2 4.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region HIP1_clath_bdg PF16515.5 EAX89920.1 - 7.7 7.2 11.6 0.42 11.2 3.3 2.5 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Gly-zipper_Omp PF13488.6 EAX89922.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX89922.1 - 0.081 13.2 3.7 0.11 12.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX89922.1 - 0.87 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif LRR_5 PF13306.6 EAX89923.1 - 1.2e-101 335.7 123.2 1.5e-27 96.1 0.8 8.1 2 2 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX89923.1 - 6.7e-23 80.2 29.5 0.00057 19.6 4.8 12.2 8 3 5 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EAX89923.1 - 0.29 11.6 38.6 0.49 10.9 0.2 10.1 6 2 4 11 11 11 0 Leucine Rich repeats (2 copies) ADK PF00406.22 EAX89924.1 - 4.4e-43 147.0 0.0 6.2e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAX89924.1 - 1.3e-23 83.9 0.0 2.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EAX89924.1 - 5e-15 55.2 0.0 8.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EAX89924.1 - 1.3e-06 29.0 0.0 3.3e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAX89924.1 - 4.9e-06 26.8 0.0 1.9e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EAX89924.1 - 0.0069 16.3 0.2 1.5 8.6 0.0 2.8 3 0 0 3 3 3 1 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EAX89924.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 EAX89924.1 - 0.12 12.0 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase RuvB_N PF05496.12 EAX89924.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ank_2 PF12796.7 EAX89925.1 - 9.2e-09 35.8 3.9 5.6 7.6 0.0 7.2 7 1 1 8 8 8 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89925.1 - 0.0028 18.0 0.1 8.5 7.3 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EAX89925.1 - 0.23 12.1 0.3 76 4.1 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Cullin PF00888.22 EAX89926.1 - 3.6e-17 62.2 26.2 2.2e-15 56.4 26.2 3.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAX89926.1 - 2e-07 30.9 1.1 2e-07 30.9 1.1 3.4 3 0 0 3 3 3 1 Cullin protein neddylation domain TFIIE_alpha PF02002.17 EAX89926.1 - 0.00082 19.2 1.3 0.0035 17.2 1.1 2.3 1 1 0 1 1 1 1 TFIIE alpha subunit VEFS-Box PF09733.9 EAX89926.1 - 0.068 13.0 2.7 0.16 11.8 2.7 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Abhydrolase_1 PF00561.20 EAX89927.1 - 3e-15 56.6 0.0 1.1e-09 38.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX89927.1 - 5.6e-08 32.3 0.0 1.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAX89927.1 - 8.3e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EAX89927.1 - 1.9e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EAX89927.1 - 0.0002 21.2 0.2 0.54 10.0 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 EAX89927.1 - 0.0005 20.2 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EAX89927.1 - 0.00085 19.0 0.0 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 EAX89927.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2235 PF09994.9 EAX89927.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) MCRA PF06100.11 EAX89929.1 - 1.8e-200 666.9 0.0 2.1e-200 666.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EAX89929.1 - 2.5e-06 27.6 0.0 6.1e-05 23.2 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DUF3244 PF11589.8 EAX89929.1 - 0.035 14.2 0.1 0.079 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Med3 PF11593.8 EAX89929.1 - 0.038 13.2 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Actin PF00022.19 EAX89930.1 - 1.2e-33 116.3 0.0 2.3e-14 52.9 0.0 3.0 1 1 2 3 3 3 3 Actin MreB_Mbl PF06723.13 EAX89930.1 - 7.3e-05 21.7 0.0 0.00013 20.9 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EAX89930.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.6 2 0 0 2 2 2 1 Cell division protein FtsA Dala_Dala_lig_C PF07478.13 EAX89930.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF3920 PF13058.6 EAX89930.1 - 0.078 13.2 0.7 0.15 12.3 0.0 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3920) Pkinase PF00069.25 EAX89932.1 - 3e-65 220.2 0.0 3.8e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX89932.1 - 3.1e-32 111.9 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX89932.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX89932.1 - 3.7e-06 26.1 0.6 0.00049 19.2 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 EAX89932.1 - 5.1e-05 23.0 0.0 0.088 12.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX89932.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_TH1 PF06017.13 EAX89932.1 - 0.0071 16.0 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Pkinase_fungal PF17667.1 EAX89932.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX89932.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FKBP_C PF00254.28 EAX89933.1 - 1.3e-11 44.7 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PSP PF04046.16 EAX89935.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX89936.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX89937.1 - 0.015 15.7 0.6 0.026 15.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX89938.1 - 4.5e-29 100.3 12.3 4.5e-29 100.3 12.3 4.5 7 1 0 7 7 7 1 Phage tail repeat like DUF4116 PF13475.6 EAX89938.1 - 0.0099 15.6 0.4 0.059 13.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) Imm32 PF15566.6 EAX89938.1 - 0.77 9.6 3.5 8.1 6.3 0.4 2.9 1 1 1 2 2 2 0 Immunity protein 32 Gp5_C PF06715.12 EAX89938.1 - 0.79 10.0 3.9 1.2e+02 3.1 0.9 4.1 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) DUF4795 PF16043.5 EAX89938.1 - 0.93 9.1 18.3 3.4 7.2 13.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX89938.1 - 1.4 9.5 14.2 20 5.8 5.5 3.7 2 2 1 3 3 3 0 YmaF family DUF240 PF03086.14 EAX89938.1 - 3.9 7.4 8.3 3.3 7.7 1.2 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF240) Trypan_PARP PF05887.11 EAX89940.1 - 0.15 12.0 9.6 0.17 11.8 9.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX89940.1 - 5 7.6 6.8 5.8 7.4 6.8 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX89941.1 - 0.019 15.4 0.4 0.023 15.1 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX89941.1 - 0.12 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX89942.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TTL PF03133.15 EAX89943.1 - 1.3e-66 224.8 0.2 3.2e-66 223.5 0.2 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX89943.1 - 1.3e-11 44.3 1.5 4.3e-05 22.9 0.0 4.0 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX89943.1 - 8.1e-08 31.8 0.0 0.0059 15.9 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX89943.1 - 2.7e-05 24.3 0.0 0.00065 19.8 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EAX89943.1 - 0.065 12.8 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF5429 PF17494.2 EAX89943.1 - 0.44 10.6 1.1 10 6.2 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5429) Ank PF00023.30 EAX89944.1 - 1.5e-19 69.5 0.7 2.3e-08 34.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX89944.1 - 1.1e-18 67.0 1.3 1.2e-10 41.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89944.1 - 4.3e-18 65.7 0.7 5.9e-18 65.2 0.7 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89944.1 - 2.5e-17 63.0 0.3 5.4e-14 52.4 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89944.1 - 2e-14 52.2 0.2 1.1e-05 25.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat SAB PF04382.13 EAX89944.1 - 0.1 12.7 0.7 13 5.9 0.2 3.0 3 0 0 3 3 3 0 SAB domain DUF3447 PF11929.8 EAX89945.1 - 6.2e-40 135.0 5.7 6.2e-40 135.0 5.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89945.1 - 2.6e-09 37.5 0.2 3.1e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89945.1 - 7.7e-09 35.9 0.9 2e-05 25.0 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89945.1 - 0.0087 16.5 1.2 76 4.4 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 EAX89945.1 - 0.023 15.0 0.0 0.82 10.1 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EAX89945.1 - 0.024 15.1 0.1 8.7 7.0 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat PaRep2a PF07903.11 EAX89946.1 - 0.075 12.9 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Myb_DNA-binding PF00249.31 EAX89948.1 - 2.3e-22 78.9 8.0 6.3e-12 45.5 2.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX89948.1 - 3.9e-16 59.0 9.7 3.8e-12 46.3 3.6 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX89948.1 - 0.00074 19.5 1.1 0.81 9.7 0.1 2.5 1 1 1 2 2 2 2 SLIDE HTH_AsnC-type PF13404.6 EAX89948.1 - 0.00092 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Myb_DNA-bind_7 PF15963.5 EAX89948.1 - 0.0026 17.6 3.7 0.0031 17.4 0.3 2.2 1 1 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAX89948.1 - 0.03 14.6 1.9 0.13 12.5 0.6 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Atg29_N PF18388.1 EAX89948.1 - 0.046 13.5 1.3 6 6.8 0.1 2.6 2 0 0 2 2 2 0 Atg29 N-terminal domain Radial_spoke PF04712.12 EAX89949.1 - 4.7e-110 368.8 17.7 6.7e-110 368.3 17.2 1.4 1 1 0 1 1 1 1 Radial spokehead-like protein Pkinase PF00069.25 EAX89950.1 - 1.3e-18 67.4 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAX89950.1 - 1.8e-10 40.2 0.6 2.5e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EAX89950.1 - 9.6e-10 38.2 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX89950.1 - 0.00089 18.7 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX89950.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Toxin_25 PF08095.11 EAX89950.1 - 0.036 14.0 1.8 0.067 13.2 1.8 1.4 1 0 0 1 1 1 0 Hefutoxin family MULE PF10551.9 EAX89951.1 - 6.4e-10 39.3 1.5 6.4e-10 39.3 1.5 2.0 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX89951.1 - 0.0018 18.3 1.1 0.0077 16.3 1.1 2.1 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX89951.1 - 0.0065 15.4 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family WRKY PF03106.15 EAX89951.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain UPF0242 PF06785.11 EAX89952.1 - 1.1 9.3 30.8 0.41 10.7 12.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 EAX89952.1 - 6.9 6.1 37.3 1.9 8.0 18.3 3.4 2 1 2 4 4 4 0 Leucine zipper Baculo_PEP_C PF04513.12 EAX89952.1 - 8 6.5 19.6 2 8.4 0.5 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 EAX89953.1 - 3e-06 27.7 0.1 0.0058 17.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX89953.1 - 3.5e-06 26.9 1.3 3.5e-06 26.9 1.3 2.9 2 2 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX89953.1 - 0.009 16.4 0.0 3.2 8.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX89953.1 - 0.063 13.9 0.4 1.8 9.2 0.0 3.3 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89954.1 - 1.8e-06 28.4 0.0 2.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89954.1 - 0.00021 21.8 0.0 0.00022 21.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX89954.1 - 0.00023 21.3 0.0 0.033 14.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX89954.1 - 0.00043 20.6 0.0 0.0012 19.2 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX89955.1 - 4.4e-72 237.6 15.4 1e-10 41.9 0.1 12.2 5 2 9 14 14 14 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX89955.1 - 5.9e-71 235.1 28.8 1.8e-13 50.8 0.1 7.7 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX89955.1 - 1.8e-66 219.3 17.6 7.2e-12 45.3 0.2 10.6 6 2 4 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89955.1 - 4e-58 186.5 12.5 0.0012 19.1 0.0 14.8 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 EAX89955.1 - 5e-53 175.4 25.1 3.3e-06 27.3 0.3 13.7 14 0 0 14 14 14 9 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX89955.1 - 8.2e-11 41.6 9.5 1.5e-10 40.7 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX89955.1 - 1.3e-07 31.3 12.2 3.1e-07 30.1 12.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAX89955.1 - 0.0045 16.9 11.9 0.013 15.4 11.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain DUF4097 PF13349.6 EAX89955.1 - 0.011 15.1 5.2 0.56 9.5 2.6 3.3 2 1 0 2 2 2 0 Putative adhesin zf-RING_2 PF13639.6 EAX89955.1 - 0.061 13.7 11.8 0.14 12.5 11.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EAX89955.1 - 0.72 9.8 12.4 1.6 8.7 12.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 EAX89957.1 - 7.4e-31 106.6 13.5 4e-15 56.2 3.2 4.9 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89957.1 - 1.1e-30 105.6 4.5 2.4e-10 40.7 0.2 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89957.1 - 2.7e-22 76.5 12.1 0.0013 19.0 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EAX89957.1 - 1.3e-21 76.0 15.3 1.5e-06 28.4 0.2 7.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX89957.1 - 7.5e-19 67.6 7.7 1.5e-08 34.8 0.4 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89957.1 - 4.5e-13 48.9 5.9 4.5e-13 48.9 5.9 4.0 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX89958.1 - 7.4e-47 157.9 17.5 3.3e-14 53.2 0.7 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89958.1 - 1.3e-43 145.6 11.1 9.4e-08 32.2 0.0 8.8 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAX89958.1 - 1.9e-39 133.5 12.4 9.3e-11 42.0 0.0 8.5 5 1 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89958.1 - 1.1e-36 124.4 19.5 6.8e-11 42.2 0.1 7.2 3 1 6 9 9 9 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX89958.1 - 3.4e-35 119.9 7.3 3.4e-35 119.9 7.3 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX89958.1 - 4.8e-32 106.4 16.4 4.9e-05 23.4 0.0 9.9 9 1 1 10 10 10 6 Ankyrin repeat MetallophosN PF16371.5 EAX89958.1 - 0.002 18.4 0.0 3 8.2 0.0 4.5 2 1 3 5 5 5 1 N terminal of Calcineurin-like phosphoesterase BRCT_2 PF16589.5 EAX89958.1 - 0.0068 16.8 4.7 8.7 6.8 0.1 5.2 3 1 2 5 5 5 1 BRCT domain, a BRCA1 C-terminus domain BLOC1_2 PF10046.9 EAX89959.1 - 2.1 8.7 8.5 0.82 10.0 3.3 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dymeclin PF09742.9 EAX89960.1 - 2.8e-09 36.0 8.8 1.1e-07 30.7 5.7 2.3 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 EAX89960.1 - 1.1e-06 27.2 17.5 1.4e-05 23.5 15.0 2.8 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Ribosomal_L37ae PF01780.19 EAX89961.1 - 1.7e-39 133.8 8.3 1.9e-39 133.6 8.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EAX89961.1 - 0.016 15.3 2.4 0.027 14.6 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lar_restr_allev PF14354.6 EAX89961.1 - 0.02 15.3 0.7 0.034 14.5 0.7 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf_UBZ PF18439.1 EAX89961.1 - 0.17 11.5 1.1 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 EAX89961.1 - 0.18 11.8 3.5 2 8.4 3.7 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 EAX89961.1 - 2.1 8.5 7.5 5.8 7.0 0.4 2.5 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 EAX89961.1 - 2.3 8.8 8.2 7.8 7.1 1.5 2.5 2 1 1 3 3 3 0 Zinc-finger double domain Ank_2 PF12796.7 EAX89962.1 - 4.3e-06 27.2 0.1 0.0011 19.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX89962.1 - 0.00094 19.1 6.3 0.00094 19.1 6.3 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX89962.1 - 0.0087 16.6 0.2 3.5 8.3 0.0 3.8 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89962.1 - 0.019 15.5 0.0 4.8 8.1 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat DUF4261 PF14080.6 EAX89962.1 - 0.28 11.3 2.2 22 5.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4261) TMP PF05017.14 EAX89963.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX89964.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP RPN2_C PF18004.1 EAX89965.1 - 2.4e-20 73.1 0.1 5.7e-11 42.6 0.1 2.0 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1770 PF08589.10 EAX89965.1 - 0.012 16.5 0.5 0.016 16.2 0.5 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) HEAT_2 PF13646.6 EAX89966.1 - 1e-08 35.4 0.0 1.2e-08 35.2 0.0 1.0 1 0 0 1 1 1 1 HEAT repeats PC_rep PF01851.22 EAX89966.1 - 0.0013 19.1 2.2 0.0013 19.1 2.2 2.6 3 0 0 3 3 3 1 Proteasome/cyclosome repeat HEAT_EZ PF13513.6 EAX89966.1 - 0.002 18.6 0.1 0.018 15.6 0.1 2.1 1 1 1 2 2 2 1 HEAT-like repeat HEAT PF02985.22 EAX89966.1 - 0.0041 17.3 0.1 0.9 10.0 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat IBN_N PF03810.19 EAX89966.1 - 0.0049 16.8 0.1 0.019 14.9 0.1 1.8 1 1 0 1 1 1 1 Importin-beta N-terminal domain DUF1702 PF08012.11 EAX89966.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Cnd1 PF12717.7 EAX89966.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PC_rep PF01851.22 EAX89967.1 - 2.4e-16 59.3 0.8 0.00042 20.6 0.0 5.1 5 0 0 5 5 5 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EAX89967.1 - 1.4e-05 25.4 0.0 0.1 13.0 0.0 3.2 3 1 1 4 4 4 3 HEAT repeats Microtub_bd PF16796.5 EAX89968.1 - 0.046 13.7 0.2 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 Microtubule binding SRP68 PF16969.5 EAX89969.1 - 2.4e-45 155.6 2.3 1.6e-34 119.9 2.6 2.3 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 RPN7 PF10602.9 EAX89969.1 - 0.016 14.9 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 EAX89969.1 - 0.32 11.2 1.9 1.6 9.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PTS_IIA PF02255.16 EAX89970.1 - 3 7.9 6.1 0.23 11.5 0.7 1.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Synaptobrevin PF00957.21 EAX89971.1 - 1.7e-23 82.2 0.2 2.8e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAX89971.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec2p PF06428.11 EAX89971.1 - 0.14 12.1 2.8 0.26 11.3 2.8 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Ank_2 PF12796.7 EAX89972.1 - 1.1e-22 80.3 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX89972.1 - 2.1e-20 72.2 0.0 3e-06 27.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX89972.1 - 2.8e-20 72.1 0.1 2.5e-09 37.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX89972.1 - 1.8e-17 63.4 0.0 6.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX89972.1 - 8e-16 56.5 0.0 0.00041 20.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF3083 PF11281.8 EAX89972.1 - 0.045 13.1 0.0 3 7.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3083) L_protein_N PF15518.6 EAX89972.1 - 0.046 13.5 0.0 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 L protein N-terminus Rad4 PF03835.15 EAX89972.1 - 0.095 12.4 0.2 7.8 6.2 0.1 2.5 2 1 1 3 3 3 0 Rad4 transglutaminase-like domain mTERF PF02536.14 EAX89972.1 - 0.1 11.5 0.0 0.27 10.1 0.0 1.7 1 1 0 1 1 1 0 mTERF DUF1897 PF09005.10 EAX89972.1 - 0.17 11.4 0.0 19 4.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Sas10_Utp3 PF04000.15 EAX89973.1 - 1.2e-08 35.5 0.1 6.2e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Helicase_C_3 PF13625.6 EAX89973.1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Methyltransf_1N PF02870.15 EAX89973.1 - 0.075 13.8 0.1 0.87 10.4 0.0 2.5 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF5344 PF17279.2 EAX89973.1 - 1.2 9.7 8.5 0.68 10.5 0.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Na_trans_assoc PF06512.13 EAX89974.1 - 0.0042 17.4 28.7 81 3.4 0.0 3.3 1 1 1 3 3 3 0 Sodium ion transport-associated DASH_Dad1 PF08649.10 EAX89974.1 - 0.057 13.6 19.9 0.38 11.0 3.0 4.1 4 0 0 4 4 4 0 DASH complex subunit Dad1 Glyco_trans_1_2 PF13524.6 EAX89974.1 - 2.4 8.6 6.3 19 5.7 0.8 2.9 1 1 1 2 2 2 0 Glycosyl transferases group 1 Bromodomain PF00439.25 EAX89975.1 - 1.7e-23 82.4 0.2 7.2e-23 80.5 0.4 2.0 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 EAX89975.1 - 1.6e-06 28.3 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAX89975.1 - 7.5e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX89975.1 - 0.0044 17.4 0.1 0.0078 16.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 EAX89976.1 - 5.8e-49 164.6 1.4 9.8e-16 58.1 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX89976.1 - 9.4e-37 124.9 0.0 1e-10 41.9 0.0 4.7 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX89976.1 - 2.2e-30 104.3 0.0 1.5e-09 38.0 0.0 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX89976.1 - 3.6e-30 103.1 0.0 2.8e-06 27.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX89976.1 - 4.4e-24 81.9 0.0 0.00091 19.5 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat L_protein_N PF15518.6 EAX89976.1 - 0.0018 18.0 0.0 2.2 8.1 0.0 3.5 1 1 3 4 4 4 1 L protein N-terminus DUF3083 PF11281.8 EAX89976.1 - 0.084 12.2 0.0 6 6.1 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3083) YfmQ PF10787.9 EAX89976.1 - 0.096 12.5 0.1 13 5.5 0.0 3.0 1 1 2 3 3 3 0 Uncharacterised protein from bacillus cereus group SF3b10 PF07189.11 EAX89976.1 - 0.12 12.5 1.6 22 5.2 0.1 3.6 4 0 0 4 4 4 0 Splicing factor 3B subunit 10 (SF3b10) DUF1897 PF09005.10 EAX89976.1 - 0.18 11.3 0.0 32 4.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) Podoplanin PF05808.11 EAX89977.1 - 3.7e-07 30.4 1.4 6.7e-07 29.5 1.4 1.4 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 EAX89977.1 - 0.0001 22.8 0.2 0.0002 21.9 0.2 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF3377 PF11857.8 EAX89977.1 - 0.012 15.5 0.6 0.033 14.1 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Amnionless PF14828.6 EAX89977.1 - 0.028 13.3 0.1 0.056 12.3 0.1 1.5 1 0 0 1 1 1 0 Amnionless ODV-E18 PF10717.9 EAX89977.1 - 0.031 14.1 0.6 0.063 13.1 0.6 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.6 EAX89977.1 - 0.1 12.9 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EAX89977.1 - 0.26 12.2 1.7 0.69 10.8 1.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OMP_b-brl_2 PF13568.6 EAX89977.1 - 0.32 11.0 3.2 1 9.4 0.6 2.4 3 0 0 3 3 3 0 Outer membrane protein beta-barrel domain VSP PF03302.13 EAX89977.1 - 1.2 7.9 5.7 1.9 7.3 5.7 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein CYYR1 PF10873.8 EAX89977.1 - 2.2 8.7 4.6 3.7 8.0 4.6 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 AAA_18 PF13238.6 EAX89978.1 - 0.00093 19.8 0.1 0.0025 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EAX89978.1 - 0.0035 17.2 0.2 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase NTPase_1 PF03266.15 EAX89978.1 - 0.0041 17.0 0.3 0.0081 16.1 0.3 1.5 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 EAX89978.1 - 0.0065 16.5 1.3 0.01 15.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAX89978.1 - 0.021 15.3 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAX89978.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EAX89978.1 - 0.15 11.7 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Gtr1_RagA PF04670.12 EAX89978.1 - 0.18 11.2 3.3 1.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Gemini_AL1_M PF08283.11 EAX89978.1 - 0.26 11.4 3.1 4.6 7.4 0.2 3.1 2 1 1 3 3 3 0 Geminivirus rep protein central domain Sigma70_ner PF04546.13 EAX89980.1 - 0.13 12.1 2.8 3.4 7.5 1.0 2.9 2 1 0 2 2 2 0 Sigma-70, non-essential region SNF2_N PF00176.23 EAX89981.1 - 9.7e-44 149.5 0.2 9.7e-44 149.5 0.2 5.0 3 3 2 5 5 5 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX89981.1 - 1.6e-19 70.3 0.0 1.6e-19 70.3 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain PqiA PF04403.13 EAX89982.1 - 1.9e-11 44.1 17.8 3.7e-08 33.4 4.7 3.2 4 0 0 4 4 4 2 Paraquat-inducible protein A Ras PF00071.22 EAX89983.1 - 6.1e-35 120.2 0.0 7.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89983.1 - 2.2e-26 92.4 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89983.1 - 2.2e-12 46.8 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX89983.1 - 6.4e-08 32.4 0.0 3.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX89983.1 - 1.4e-06 28.3 0.3 0.021 14.7 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX89983.1 - 1.5e-05 24.5 0.1 2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX89983.1 - 8.8e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX89983.1 - 0.0002 21.2 0.2 0.0023 17.7 0.2 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EAX89983.1 - 0.0009 18.7 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EAX89983.1 - 0.0022 18.4 0.0 0.0047 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 EAX89983.1 - 0.016 15.0 0.4 3.4 7.4 0.0 2.7 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EAX89983.1 - 0.028 13.7 0.1 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EAX89983.1 - 0.05 13.3 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAX89983.1 - 0.071 13.4 0.0 0.92 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EAX89983.1 - 0.083 12.0 0.2 3.2 6.8 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 EAX89983.1 - 0.089 12.8 0.1 1.3 9.1 0.0 2.1 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF4618 PF15397.6 EAX89984.1 - 0.0014 18.1 21.3 0.11 11.8 11.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) UPF0242 PF06785.11 EAX89984.1 - 0.0025 17.9 28.8 0.11 12.6 28.8 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus End3 PF12761.7 EAX89984.1 - 0.0073 16.5 17.4 0.1 12.7 5.9 2.4 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Jnk-SapK_ap_N PF09744.9 EAX89984.1 - 0.01 16.0 24.9 0.044 14.0 12.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 EAX89984.1 - 0.02 14.2 25.3 0.43 9.9 4.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EAX89984.1 - 0.022 14.4 21.0 0.16 11.5 3.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein CRR7 PF12095.8 EAX89984.1 - 0.024 15.1 1.1 0.024 15.1 1.1 3.1 1 1 3 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 SKA2 PF16740.5 EAX89984.1 - 0.027 14.3 19.4 0.15 11.9 11.0 3.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 PRANC PF09372.10 EAX89984.1 - 0.039 14.3 5.2 0.074 13.4 0.1 2.4 1 1 1 2 2 2 0 PRANC domain Imm30 PF15565.6 EAX89984.1 - 0.043 13.9 8.6 0.048 13.7 0.7 3.0 1 1 2 3 3 3 0 Immunity protein 30 LMP PF04778.12 EAX89984.1 - 0.047 13.6 18.9 0.75 9.7 18.9 2.1 1 1 0 1 1 1 0 LMP repeated region Fib_alpha PF08702.10 EAX89984.1 - 0.048 13.8 21.5 0.33 11.1 11.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 EAX89984.1 - 0.071 13.0 1.4 0.071 13.0 1.4 3.9 4 1 2 6 6 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PDH PF02153.17 EAX89984.1 - 0.11 11.4 8.0 0.15 11.1 1.1 2.2 2 0 0 2 2 2 0 Prephenate dehydrogenase T3SSipB PF16535.5 EAX89984.1 - 0.12 12.9 6.2 0.13 12.7 0.8 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB ANAPC4 PF12896.7 EAX89984.1 - 0.13 11.7 10.1 0.13 11.8 0.9 2.6 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 FliJ PF02050.16 EAX89984.1 - 0.15 12.3 16.7 0.22 11.8 6.6 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein HIT PF01230.23 EAX89984.1 - 0.15 12.8 1.6 0.66 10.7 0.1 2.2 2 1 0 2 2 2 0 HIT domain AAA_13 PF13166.6 EAX89984.1 - 0.15 10.7 19.5 0.2 10.3 19.5 1.0 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EAX89984.1 - 0.17 11.2 11.8 1.4 8.2 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 EAX89984.1 - 0.21 11.9 18.7 0.45 10.8 3.3 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) HAP1_N PF04849.13 EAX89984.1 - 0.25 10.5 26.9 0.37 10.0 16.2 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region LXG PF04740.12 EAX89984.1 - 0.29 10.8 14.4 0.42 10.3 14.4 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily YtxH PF12732.7 EAX89984.1 - 0.3 11.7 2.6 34 5.1 2.6 2.6 1 1 0 1 1 1 0 YtxH-like protein Baculo_PEP_C PF04513.12 EAX89984.1 - 0.3 11.1 10.7 6.2 6.9 3.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 EAX89984.1 - 0.37 10.6 17.0 0.03 14.2 5.7 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Metal_resist PF13801.6 EAX89984.1 - 0.46 10.7 2.5 0.54 10.5 0.4 2.0 2 1 1 3 3 2 0 Heavy-metal resistance Spc7 PF08317.11 EAX89984.1 - 0.57 9.0 25.3 0.12 11.3 13.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EAX89984.1 - 0.71 10.4 25.3 1 9.9 23.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 EAX89984.1 - 1.1 9.7 25.5 2.6 8.6 3.8 3.6 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Exonuc_VII_L PF02601.15 EAX89984.1 - 1.1 8.7 12.5 1.8 8.1 12.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 EAX89984.1 - 1.1 8.9 9.9 1.8 8.3 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CorA PF01544.18 EAX89984.1 - 1.3 8.3 13.5 2.5 7.3 13.5 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein GBP_C PF02841.14 EAX89984.1 - 1.5 8.2 22.4 0.31 10.4 10.0 2.0 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.19 EAX89984.1 - 1.5 6.6 14.5 1.9 6.3 14.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4279 PF14106.6 EAX89984.1 - 1.8 8.8 6.6 0.58 10.4 0.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4279) SseC PF04888.12 EAX89984.1 - 1.9 8.0 10.4 0.41 10.2 2.8 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family XLF PF09302.11 EAX89984.1 - 2.1 8.5 16.7 17 5.5 16.7 2.3 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF1664 PF07889.12 EAX89984.1 - 2.3 8.3 13.1 2.1 8.4 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EAX89984.1 - 2.3 8.7 10.6 6.9e+02 0.8 10.6 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AAA_32 PF13654.6 EAX89984.1 - 3.8 6.2 17.1 0.47 9.2 10.7 1.9 1 1 1 2 2 2 0 AAA domain CENP-H PF05837.12 EAX89984.1 - 4 7.9 21.1 0.53 10.7 8.9 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 EAX89984.1 - 6.7 7.4 21.7 6.4 7.5 7.8 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Prefoldin PF02996.17 EAX89984.1 - 7.4 6.5 20.7 5.4 7.0 2.3 3.3 3 0 0 3 3 3 0 Prefoldin subunit Nsp1_C PF05064.13 EAX89984.1 - 7.9 6.3 18.5 5.3 6.9 3.7 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region FAD-SLDH PF12318.8 EAX89984.1 - 8.5 6.4 6.1 28 4.7 0.9 2.8 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase KELK PF15796.5 EAX89984.1 - 9.8 6.7 26.7 1.3 9.5 10.5 3.2 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cytomega_UL84 PF06284.11 EAX89985.1 - 0.22 9.9 1.6 0.23 9.9 1.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein LRR_6 PF13516.6 EAX89986.1 - 6.9e-19 66.2 38.1 0.0005 19.9 0.1 12.3 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 EAX89986.1 - 0.012 16.1 38.7 0.57 10.7 2.1 7.6 6 1 3 9 9 9 0 Leucine Rich repeats (2 copies) IMPa_N_2 PF18650.1 EAX89986.1 - 0.019 14.3 0.7 0.042 13.1 0.0 1.9 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain LRR_1 PF00560.33 EAX89986.1 - 0.019 15.4 20.4 40 5.3 0.2 9.5 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_2 PF07723.13 EAX89986.1 - 0.075 13.7 7.3 54 4.7 0.3 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Ras PF00071.22 EAX89987.1 - 1.7e-55 187.1 0.1 2e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX89987.1 - 8.6e-33 113.1 0.1 1.2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX89987.1 - 5.8e-17 61.7 0.0 7.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX89987.1 - 3.7e-08 33.0 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX89987.1 - 6.2e-07 29.5 0.0 8.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX89987.1 - 2.3e-06 27.1 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 EAX89987.1 - 0.00034 20.0 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EAX89987.1 - 0.0016 18.0 0.2 0.011 15.3 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EAX89987.1 - 0.0031 17.9 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX89987.1 - 0.0038 17.5 0.1 0.0078 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAX89987.1 - 0.0041 17.0 0.1 0.076 12.9 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EAX89987.1 - 0.0066 16.2 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAX89987.1 - 0.0071 16.4 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX89987.1 - 0.008 16.6 0.1 0.027 14.9 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EAX89987.1 - 0.0092 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EAX89987.1 - 0.031 14.1 0.1 2.4 7.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EAX89987.1 - 0.035 14.6 0.1 0.047 14.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EAX89987.1 - 0.04 13.9 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EAX89987.1 - 0.051 13.7 0.1 0.46 10.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAX89987.1 - 0.059 13.1 0.0 0.33 10.7 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EAX89987.1 - 0.081 12.5 0.5 0.48 10.0 0.1 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EAX89987.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EAX89987.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 EAX89987.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EAX89987.1 - 0.13 12.9 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAX89987.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase VirE PF05272.11 EAX89987.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_5 PF07728.14 EAX89987.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4108 PF13390.6 EAX89988.1 - 1.2e-63 213.4 6.7 1.3e-63 213.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX89990.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX89990.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX89990.1 - 0.00016 21.7 3.0 0.00036 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX89990.1 - 0.00025 20.8 0.3 0.58 9.9 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX89990.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX89990.1 - 0.0016 18.2 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX89990.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX89990.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX89990.1 - 0.067 12.8 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX89990.1 - 0.082 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX89990.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3839 PF12943.7 EAX89992.1 - 1.3e-152 506.1 12.6 1.6e-152 505.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX89992.1 - 0.033 14.7 2.1 0.1 13.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX89992.1 - 0.095 13.3 5.1 0.19 12.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX89992.1 - 0.31 11.5 6.4 1.1 9.7 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX89993.1 - 3.8e-30 104.0 0.1 4.5e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX89993.1 - 0.11 12.4 0.3 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DNA_pol_B_2 PF03175.13 EAX89994.1 - 2.9e-10 39.6 3.2 9.6e-10 37.9 2.6 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX89995.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX89995.1 - 0.091 12.7 0.5 0.13 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX89996.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX89996.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MGC-24 PF05283.11 EAX89997.1 - 2.3 8.7 5.0 3.4 8.1 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX89998.1 - 0.043 14.2 0.2 0.053 14.0 0.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX89998.1 - 0.093 11.7 0.1 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Collagen_bind_2 PF12904.7 EAX89999.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase FYVE_2 PF02318.16 EAX90000.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3447 PF11929.8 EAX90001.1 - 1.5e-07 31.2 3.8 1.7e-07 31.1 2.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX90001.1 - 5.3e-05 23.3 1.7 6.2 7.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EAX90001.1 - 0.0062 16.8 0.4 2.4 8.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90001.1 - 0.0068 17.0 0.2 0.11 13.1 0.2 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1450 PF07293.11 EAX90001.1 - 0.01 15.6 1.2 0.037 13.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Ank_2 PF12796.7 EAX90003.1 - 1e-49 167.0 19.2 2.6e-09 37.5 0.1 6.7 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90003.1 - 5.7e-42 141.6 15.8 6.8e-08 32.9 0.0 11.6 7 4 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90003.1 - 3.2e-36 122.9 5.6 6.9e-06 26.2 0.0 11.0 8 3 4 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX90003.1 - 7.5e-21 73.6 9.0 4e-05 23.9 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat Ank_3 PF13606.6 EAX90003.1 - 2.3e-20 70.5 19.4 0.0013 19.1 0.0 12.2 14 0 0 14 14 14 5 Ankyrin repeat Furin-like_2 PF15913.5 EAX90004.1 - 1.3e-32 112.1 193.0 0.0013 18.8 10.0 11.6 1 1 10 11 11 11 11 Furin-like repeat, cysteine-rich Gly_rich PF12810.7 EAX90004.1 - 1.9e-09 37.8 33.2 3.9e-09 36.8 33.2 1.5 1 0 0 1 1 1 1 Glycine rich protein Rep_1B PF17873.1 EAX90004.1 - 0.1 12.5 18.3 2.9 7.8 0.0 7.7 10 0 0 10 10 10 0 Replicase polyprotein 1ab FlaC_arch PF05377.11 EAX90005.1 - 0.037 14.4 1.4 0.037 14.4 1.4 7.5 4 3 4 8 8 8 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 EAX90005.1 - 0.057 11.6 69.7 0.14 10.4 27.0 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Bap31_Bap29_C PF18035.1 EAX90005.1 - 0.067 13.2 1.1 0.067 13.2 1.1 6.4 6 2 0 6 6 6 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 EAX90005.1 - 0.86 9.8 62.2 0.43 10.8 23.3 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF5494 PF17598.2 EAX90005.1 - 4.2 7.5 7.3 11 6.2 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5494) OmpH PF03938.14 EAX90005.1 - 4.6 7.6 81.9 0.094 13.1 17.6 4.8 1 1 4 5 5 5 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 EAX90005.1 - 5.8 7.2 29.4 2.8 8.3 2.5 5.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Tub PF01167.18 EAX90006.1 - 2e-07 31.0 1.5 8.3e-05 22.5 0.3 2.1 1 1 0 2 2 2 2 Tub family DUF4909 PF16253.5 EAX90006.1 - 0.048 13.5 2.9 3.9 7.3 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4909) Toxin-JAB1 PF15659.6 EAX90006.1 - 0.067 13.5 1.0 13 6.2 0.1 2.4 1 1 0 2 2 2 0 JAB-like toxin 1 Y_phosphatase2 PF03162.13 EAX90007.1 - 1.1e-43 148.7 0.0 1.7e-43 148.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EAX90007.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAX90007.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4373 PF14297.6 EAX90008.1 - 4.9 8.0 8.3 14 6.6 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4373) Radical_SAM PF04055.21 EAX90009.1 - 1.1e-14 55.2 3.8 4.6e-13 49.9 0.1 2.6 2 0 0 2 2 2 2 Radical SAM superfamily Fer4_12 PF13353.6 EAX90009.1 - 3.8e-10 40.2 3.4 5.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EAX90009.1 - 3.9e-05 23.8 1.4 0.001 19.2 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain PyrI_C PF02748.15 EAX90009.1 - 8.4 6.4 8.8 2.9 7.9 0.4 3.3 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Myb_DNA-binding PF00249.31 EAX90010.1 - 2.1e-29 101.4 6.3 4.8e-16 58.7 1.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90010.1 - 3e-24 85.0 1.8 1e-15 57.7 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX90010.1 - 3.6e-06 26.8 0.2 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX90010.1 - 6e-05 23.0 0.0 0.011 15.7 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX90010.1 - 0.0035 17.5 0.1 2 8.7 0.0 2.3 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX90010.1 - 0.0061 16.6 1.0 0.93 9.6 0.0 2.2 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX90010.1 - 0.091 13.0 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX90010.1 - 0.24 11.8 9.3 1.8 9.0 2.2 3.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EAX90010.1 - 1.4 9.0 4.1 3.8 7.7 2.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain FERM_F2 PF18377.1 EAX90011.1 - 0.016 15.1 0.2 0.019 14.9 0.2 1.1 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain HBM PF16591.5 EAX90011.1 - 0.017 14.5 0.1 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF2951 PF11166.8 EAX90011.1 - 0.24 11.7 2.0 0.52 10.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Cyclin_N PF00134.23 EAX90012.1 - 0.0029 17.3 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EAX90012.1 - 0.031 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Protocadherin PF08374.11 EAX90012.1 - 1.4 8.8 5.7 2.4 8.1 5.7 1.2 1 0 0 1 1 1 0 Protocadherin Peptidase_S49_N PF08496.10 EAX90012.1 - 1.9 8.5 3.6 3 7.9 3.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NPL PF17800.1 EAX90013.1 - 0.1 13.1 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin-like domain Ras PF00071.22 EAX90014.1 - 1.6e-46 157.9 0.1 1.8e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90014.1 - 2.6e-27 95.4 0.0 3.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90014.1 - 7.1e-18 64.7 0.0 9.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX90014.1 - 8.1e-08 31.9 0.0 1.1e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX90014.1 - 4.5e-06 26.7 0.0 7.6e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX90014.1 - 3.3e-05 23.5 0.2 0.00085 18.9 0.1 2.4 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX90014.1 - 8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX90014.1 - 9.7e-05 21.9 0.0 0.00063 19.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 EAX90014.1 - 0.0029 16.8 0.4 1.1 8.3 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MeaB PF03308.16 EAX90014.1 - 0.003 16.6 0.1 0.0052 15.8 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EAX90014.1 - 0.0097 15.8 0.3 0.26 11.2 0.0 2.3 1 1 2 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 EAX90014.1 - 0.01 16.1 0.3 0.022 15.0 0.2 1.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAX90014.1 - 0.036 13.8 0.3 0.29 10.9 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX90014.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAX90014.1 - 0.15 12.1 0.2 0.41 10.7 0.2 2.1 1 1 0 1 1 1 0 Dynamin family Gly_rich PF12810.7 EAX90016.1 - 5.4e-40 137.8 27.1 6.3e-40 137.6 27.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Pkinase PF00069.25 EAX90017.1 - 1.4e-34 119.7 0.0 2.9e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90017.1 - 3.5e-28 98.6 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX90017.1 - 5.1e-07 29.3 0.0 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX90017.1 - 0.0044 15.8 0.1 0.0044 15.8 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Prefoldin PF02996.17 EAX90017.1 - 0.019 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit ZapB PF06005.12 EAX90017.1 - 0.13 12.7 0.6 0.13 12.7 0.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB BACK PF07707.15 EAX90018.1 - 0.022 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Pkinase PF00069.25 EAX90019.1 - 1.7e-66 224.3 0.0 2.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90019.1 - 1.3e-39 136.1 0.0 1.7e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX90019.1 - 7.8e-07 29.6 0.3 1.7e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EAX90019.1 - 0.0061 15.9 0.1 0.032 13.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX90019.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EAX90019.1 - 0.028 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EAX90019.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MetOD2 PF18548.1 EAX90020.1 - 0.052 13.7 3.7 1.4 9.0 0.3 3.0 3 0 0 3 3 3 0 Metanogen output domain 2 Fmp27_SW PF10305.9 EAX90020.1 - 2.1 9.1 5.8 1.2 9.9 0.3 2.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain PDEase_I PF00233.19 EAX90021.1 - 1.9e-12 47.4 3.4 1.3e-10 41.4 3.4 2.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 EAX90021.1 - 1.6e-05 25.2 0.0 0.0091 16.3 0.0 2.4 2 0 0 2 2 2 2 GAF domain EF-G-binding_N PF07299.11 EAX90022.1 - 0.00069 20.1 5.4 0.023 15.2 1.3 3.8 2 0 0 2 2 2 2 Elongation factor G-binding protein, N-terminal CAAP1 PF15335.6 EAX90022.1 - 0.1 13.1 0.5 1.6 9.3 0.1 3.1 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Gly_rich PF12810.7 EAX90023.1 - 6.8e-54 183.3 34.6 8.4e-54 183.1 34.6 1.1 1 0 0 1 1 1 1 Glycine rich protein Avl9 PF09794.9 EAX90024.1 - 3e-43 148.0 0.0 4.4e-27 94.8 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EAX90024.1 - 2.8e-07 30.5 0.1 6.2e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 EAX90024.1 - 6e-05 23.1 0.2 0.00041 20.4 0.1 2.2 1 1 1 2 2 2 1 DENN (AEX-3) domain SMYLE_N PF18615.1 EAX90025.1 - 1.1 8.8 5.3 1.7 8.2 5.3 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain ChlamPMP_M PF07548.11 EAX90025.1 - 1.4 8.9 9.7 3.1 7.7 9.7 1.5 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain AMPKBI PF04739.15 EAX90025.1 - 7.2 7.0 12.2 22 5.4 0.5 3.0 1 1 1 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain DUF3839 PF12943.7 EAX90026.1 - 8.4e-158 523.1 13.9 1e-157 522.8 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX90026.1 - 2.8 8.4 8.0 1.5 9.3 0.5 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX90027.1 - 0.02 15.4 0.6 0.041 14.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pkinase PF00069.25 EAX90028.1 - 4.6e-63 213.0 0.4 5.9e-63 212.7 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90028.1 - 7.2e-40 136.9 0.1 8.5e-40 136.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX90028.1 - 4.3e-07 29.5 0.0 0.00038 19.9 0.0 2.3 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EAX90028.1 - 6.5e-05 22.6 1.5 0.0043 16.7 1.5 2.2 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EAX90028.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX90028.1 - 0.0074 15.1 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAX90028.1 - 0.017 14.8 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX90028.1 - 0.045 13.1 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX90028.1 - 0.064 12.2 0.1 0.23 10.4 0.0 1.7 1 1 0 2 2 2 0 Haspin like kinase domain DUF2207 PF09972.9 EAX90029.1 - 0.0024 16.7 0.0 0.0042 15.9 0.0 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 EAX90029.1 - 0.0045 16.8 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EAX90029.1 - 0.013 15.4 10.5 0.25 11.3 10.5 2.7 1 1 0 1 1 1 0 TMEM154 protein family Thioredoxin PF00085.20 EAX90030.1 - 1.4e-11 44.3 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX90030.1 - 0.00049 20.4 0.0 0.035 14.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 EAX90030.1 - 0.029 14.2 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EAX90030.1 - 0.029 14.1 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 EAX90030.1 - 0.043 14.3 0.1 0.093 13.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 EAX90030.1 - 0.072 13.1 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EAX90030.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin MatE PF01554.18 EAX90031.1 - 3.8e-12 46.1 3.9 4.9e-12 45.8 3.9 1.1 1 0 0 1 1 1 1 MatE Chlam_OMP PF01308.17 EAX90031.1 - 0.078 11.7 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia major outer membrane protein Guanylate_cyc PF00211.20 EAX90032.1 - 5.2e-43 146.8 0.1 1.2e-42 145.7 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX90032.1 - 1.8e-05 24.9 0.9 7.6e-05 22.9 0.4 2.3 1 1 1 2 2 2 1 PAS domain PAS PF00989.25 EAX90032.1 - 0.0018 18.2 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAX90032.1 - 0.095 12.8 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF3972 PF13118.6 EAX90032.1 - 0.18 12.2 4.6 1.2 9.6 0.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DUF1640 PF07798.11 EAX90032.1 - 1.8 8.6 6.4 1.2 9.1 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Pox_A32 PF04665.12 EAX90033.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX90033.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX90033.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX90033.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX90034.1 - 2.6e-43 146.4 0.1 3.5e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX90035.1 - 2.8e-154 511.6 12.6 3.5e-154 511.3 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90035.1 - 0.024 15.1 2.1 0.11 13.0 0.3 2.1 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAX90035.1 - 0.089 13.1 1.7 25 5.3 0.1 3.8 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX90035.1 - 0.28 11.7 5.9 1.6 9.3 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX90035.1 - 1.9 9.0 6.3 0.65 10.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX90037.1 - 0.053 14.0 0.4 0.13 12.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX90038.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3447 PF11929.8 EAX90040.1 - 2e-38 130.2 8.0 2e-38 130.2 8.0 2.9 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90040.1 - 1.1e-24 86.8 6.1 4.1e-18 65.8 0.6 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90040.1 - 9.8e-22 76.4 0.7 3.3e-08 33.6 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX90040.1 - 4.5e-20 71.7 2.1 4.4e-10 39.9 0.1 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90040.1 - 1e-15 57.5 6.1 3.2e-09 36.9 0.9 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90040.1 - 7.1e-15 53.6 3.8 0.00043 20.5 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat Mic1 PF07035.12 EAX90040.1 - 0.019 14.7 0.1 0.088 12.5 0.0 2.1 2 1 0 2 2 2 0 Colon cancer-associated protein Mic1-like PTCB-BRCT PF12738.7 EAX90040.1 - 0.13 12.2 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 twin BRCT domain Mlf1IP PF10248.9 EAX90041.1 - 3.7e-12 46.5 3.3 3.7e-12 46.5 3.3 2.3 1 1 1 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Flocculin PF00624.18 EAX90041.1 - 0.26 11.5 2.1 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 Flocculin repeat Ank_4 PF13637.6 EAX90043.1 - 1.9e-19 69.7 3.3 5.3e-10 39.6 0.4 4.4 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90043.1 - 5e-19 68.1 2.0 4e-10 39.7 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90043.1 - 1.7e-17 63.8 1.4 4.1e-15 56.1 0.3 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX90043.1 - 6.7e-17 61.2 12.6 2e-16 59.7 4.8 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Ank PF00023.30 EAX90043.1 - 1.2e-15 57.2 2.4 2.8e-07 30.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX90043.1 - 2.4e-13 48.9 4.1 3.7e-06 26.8 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ish1 PF10281.9 EAX90043.1 - 0.04 14.2 0.1 0.17 12.2 0.1 2.2 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF3839 PF12943.7 EAX90044.1 - 1.4e-143 476.5 9.9 1.7e-143 476.3 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX90044.1 - 0.17 12.4 1.8 4.8 7.7 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX90044.1 - 1 9.9 6.5 4 8.0 0.5 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX90046.1 - 1.7e-25 88.8 28.5 9.9e-24 83.2 5.3 6.3 5 1 0 5 5 5 3 Phage tail repeat like DUF4116 PF13475.6 EAX90046.1 - 0.12 12.1 0.1 0.42 10.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) SL4P PF17618.2 EAX90047.1 - 0.24 11.5 2.9 31 4.7 2.8 2.4 1 1 0 1 1 1 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX90048.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90049.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-binding PF00249.31 EAX90050.1 - 2.9e-27 94.6 1.8 2.5e-14 53.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90050.1 - 1.3e-19 70.2 4.0 2.4e-12 46.9 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain B3 PF02362.21 EAX90050.1 - 0.0087 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 B3 DNA binding domain Myb_DNA-bind_7 PF15963.5 EAX90050.1 - 0.0093 15.8 0.2 0.057 13.3 0.0 2.1 1 1 1 2 2 2 1 Myb DNA-binding like DUF4763 PF15960.5 EAX90050.1 - 0.057 12.7 0.1 0.13 11.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) SLIDE PF09111.10 EAX90050.1 - 0.13 12.3 1.8 0.56 10.2 0.2 2.6 2 1 1 3 3 3 0 SLIDE Skp1 PF01466.19 EAX90050.1 - 0.14 12.3 0.0 57 3.9 0.0 3.3 3 1 0 3 3 3 0 Skp1 family, dimerisation domain SHIPPO-rpt PF07004.12 EAX90051.1 - 3.8e-09 37.0 49.9 0.099 13.6 3.3 10.1 10 1 0 10 10 10 5 Sperm-tail PG-rich repeat WD40 PF00400.32 EAX90052.1 - 3.9e-14 52.8 13.4 0.035 15.0 0.2 9.9 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX90052.1 - 1e-08 35.3 0.0 0.0016 18.7 0.0 5.2 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX90052.1 - 0.00098 18.5 3.8 0.12 11.7 1.5 3.4 1 1 1 2 2 2 2 WD40-like domain Kelch_2 PF07646.15 EAX90052.1 - 0.038 14.0 0.2 25 5.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif AAA_23 PF13476.6 EAX90052.1 - 0.11 13.0 3.5 0.25 11.8 3.5 1.5 1 0 0 1 1 1 0 AAA domain PQQ PF01011.21 EAX90052.1 - 0.17 11.9 0.0 3.8 7.6 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat HMG_box PF00505.19 EAX90053.1 - 7.2e-05 23.1 0.7 7.2e-05 23.1 0.7 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX90053.1 - 0.0031 18.1 0.2 0.0031 18.1 0.2 1.9 2 1 0 2 2 2 1 HMG-box domain MULE PF10551.9 EAX90054.1 - 2.2e-11 44.0 0.1 4.4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX90054.1 - 0.065 13.6 0.5 2 8.8 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX90054.1 - 0.14 12.5 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 PWI domain FLYWCH PF04500.16 EAX90054.1 - 0.14 12.3 3.3 0.26 11.4 3.3 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain GPS2_interact PF15784.5 EAX90056.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX90056.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX90057.1 - 0.081 12.9 11.3 0.13 12.3 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX90058.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX90059.1 - 0.016 15.6 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX90059.1 - 3.2 8.4 6.3 7.6 7.2 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAX90060.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX90060.1 - 0.095 12.7 0.3 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) RRM_1 PF00076.22 EAX90061.1 - 4.1e-60 199.5 11.3 1.2e-16 60.3 0.3 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX90061.1 - 2.6e-13 49.9 3.5 0.021 14.9 0.1 4.6 4 1 0 4 4 4 4 RNA recognition motif RRM_3 PF08777.11 EAX90061.1 - 3.2e-10 40.0 7.1 0.0018 18.3 0.4 4.9 5 0 0 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.6 EAX90061.1 - 2.9e-08 33.6 2.0 0.028 14.4 0.0 3.9 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EAX90061.1 - 0.038 14.2 9.3 6.1 7.0 0.5 5.0 4 2 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 EAX90061.1 - 0.058 13.5 0.0 25 5.0 0.0 3.3 2 0 0 2 2 2 0 Limkain b1 RRM_1 PF00076.22 EAX90062.1 - 3.1e-42 142.2 6.4 2.8e-16 59.1 0.0 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX90062.1 - 2.6e-11 43.5 1.7 0.018 15.1 0.1 4.6 4 1 0 4 4 4 4 RNA recognition motif RRM_3 PF08777.11 EAX90062.1 - 8.3e-09 35.4 1.4 0.011 15.8 0.0 4.1 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 EAX90062.1 - 3.1e-05 23.9 0.6 0.025 14.6 0.0 3.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EAX90062.1 - 0.0045 17.2 3.7 13 6.0 0.1 4.3 4 2 0 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 EAX90062.1 - 0.075 13.1 0.0 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Limkain b1 Ribosomal_S24e PF01282.19 EAX90063.1 - 4.1e-29 100.4 0.1 6.6e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAX90063.1 - 0.00098 19.0 1.1 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Ribosomal_S24e PF01282.19 EAX90064.1 - 4.1e-29 100.4 0.1 6.6e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAX90064.1 - 0.00098 19.0 1.1 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) SYCE1 PF15233.6 EAX90065.1 - 0.0058 16.7 1.4 0.0058 16.7 1.4 1.6 1 1 1 2 2 2 1 Synaptonemal complex central element protein 1 DASH_Dad2 PF08654.10 EAX90065.1 - 0.024 15.1 0.3 0.038 14.4 0.3 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 HALZ PF02183.18 EAX90065.1 - 0.089 13.0 1.2 0.22 11.8 1.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper APG6_N PF17675.1 EAX90065.1 - 0.096 13.2 4.5 0.13 12.7 4.5 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EAX90065.1 - 0.15 11.9 0.6 0.29 10.9 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 EAX90065.1 - 0.25 11.8 3.1 0.38 11.2 0.7 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_L2_C PF03947.18 EAX90066.1 - 1.7e-39 134.9 2.4 2.8e-39 134.2 2.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAX90066.1 - 9.2e-17 60.8 0.0 4e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ras PF00071.22 EAX90067.1 - 1.6e-45 154.6 0.1 1.8e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90067.1 - 1.2e-28 99.7 0.0 2.2e-28 98.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90067.1 - 1.5e-15 57.1 0.0 1.8e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX90067.1 - 1.8e-07 31.2 0.0 2.4e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX90067.1 - 6.4e-06 25.7 0.0 7.8e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX90067.1 - 0.00015 21.7 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX90067.1 - 0.00018 21.0 0.0 0.00029 20.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX90067.1 - 0.0012 18.4 0.0 0.095 12.2 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAX90067.1 - 0.0019 17.8 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 EAX90067.1 - 0.0019 17.9 0.3 0.22 11.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain TniB PF05621.11 EAX90067.1 - 0.0099 15.3 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein Tnp_22_trimer PF17489.2 EAX90067.1 - 0.016 15.2 0.3 0.027 14.5 0.3 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain AAA PF00004.29 EAX90067.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX90067.1 - 0.084 13.1 0.0 0.66 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAX90067.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Dynamin family DUF563 PF04577.14 EAX90068.1 - 0.00016 21.9 0.6 0.00051 20.3 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF563) UNC45-central PF11701.8 EAX90069.1 - 0.0077 16.2 1.2 0.069 13.1 0.0 2.8 2 2 1 3 3 3 1 Myosin-binding striated muscle assembly central Exo70 PF03081.15 EAX90069.1 - 0.039 13.0 2.0 1.8 7.6 1.2 2.3 2 0 0 2 2 2 0 Exo70 exocyst complex subunit ATP_bind_2 PF03668.15 EAX90069.1 - 0.091 12.0 0.1 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 P-loop ATPase protein family DUF5333 PF17267.2 EAX90069.1 - 0.1 12.8 0.0 20 5.4 0.0 3.1 2 1 2 4 4 4 0 Family of unknown function (DUF5333) TetR_C_24 PF17932.1 EAX90069.1 - 0.11 12.8 0.3 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RRM_1 PF00076.22 EAX90070.1 - 1.2e-16 60.3 0.2 3e-16 59.0 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EAX90070.1 - 7.6e-10 39.3 6.3 1.6e-09 38.2 6.3 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 EAX90070.1 - 0.0002 21.4 0.0 0.00052 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Ldh_1_N PF00056.23 EAX90071.1 - 4e-28 98.3 0.0 6.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX90071.1 - 1.6e-20 73.7 0.0 2.4e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX90071.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons S10_plectin PF03501.15 EAX90072.1 - 4.3e-27 94.0 0.0 5.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_5 PF01022.20 EAX90072.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Myb_DNA-binding PF00249.31 EAX90073.1 - 3.1e-27 94.5 1.8 3.6e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90073.1 - 2.2e-22 79.1 3.2 4.5e-13 49.2 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90073.1 - 0.007 16.4 0.4 0.56 10.3 0.1 2.5 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_2 PF08914.11 EAX90073.1 - 0.019 15.1 1.2 1.4 9.2 0.0 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX90073.1 - 0.25 11.8 4.1 1.2 9.6 0.1 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_C54 PF03416.19 EAX90074.1 - 2.7e-43 148.4 0.0 3.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Pox_MCEL PF03291.16 EAX90075.1 - 3.1e-55 187.6 1.2 3.8e-55 187.3 1.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EAX90075.1 - 1.3e-07 32.3 0.0 2.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX90075.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX90075.1 - 0.00022 21.8 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EAX90075.1 - 0.00031 20.0 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 EAX90075.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain EHD_N PF16880.5 EAX90075.1 - 0.08 12.9 0.2 0.08 12.9 0.2 2.0 2 0 0 2 2 2 0 N-terminal EH-domain containing protein TM2 PF05154.16 EAX90077.1 - 7e-16 58.3 9.0 1.2e-15 57.5 9.0 1.4 1 0 0 1 1 1 1 TM2 domain Ank_4 PF13637.6 EAX90078.1 - 4.1e-88 288.7 18.5 6.6e-14 52.1 0.1 8.6 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX90078.1 - 5.1e-88 286.0 6.5 1.1e-07 32.0 0.0 10.0 10 0 0 10 10 10 10 Ankyrin repeat Ank_2 PF12796.7 EAX90078.1 - 8.7e-81 266.6 42.5 1.8e-17 63.7 2.5 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90078.1 - 2.7e-80 263.4 35.3 2.2e-11 43.8 0.1 8.6 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90078.1 - 3.1e-69 220.6 10.9 1.7e-05 24.8 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Peptidase_M16 PF00675.20 EAX90078.1 - 4.1e-10 39.8 13.0 1.4 8.9 0.1 7.2 1 1 7 8 8 8 5 Insulinase (Peptidase family M16) AnkUBD PF18418.1 EAX90078.1 - 7e-06 26.1 0.5 1.4e+02 2.7 0.0 7.5 1 1 8 9 9 9 0 Ankyrin ubiquitin-binding domain DHBP_synthase PF00926.19 EAX90078.1 - 6.4e-05 22.6 4.4 12 5.3 0.0 6.3 2 1 6 8 8 8 0 3,4-dihydroxy-2-butanone 4-phosphate synthase KdgM PF06178.13 EAX90078.1 - 9.1e-05 22.2 6.2 1.4 8.5 0.2 3.9 1 1 3 4 4 4 3 Oligogalacturonate-specific porin protein (KdgM) DUF1018 PF06252.12 EAX90078.1 - 0.00042 21.3 2.6 13 6.8 0.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1018) Env-gp36 PF09590.10 EAX90078.1 - 0.0022 16.5 1.8 2.2 6.6 0.1 3.2 1 1 3 4 4 4 2 Lentivirus surface glycoprotein DUF613 PF04764.12 EAX90078.1 - 0.0086 16.2 11.7 5.3 7.2 0.2 4.2 1 1 3 4 4 4 2 Protein of unknown function (DUF613) Importin_rep_5 PF18816.1 EAX90078.1 - 0.0099 16.2 8.1 1.2e+02 3.0 0.0 6.0 7 0 0 7 7 7 0 Importin repeat SAB PF04382.13 EAX90078.1 - 0.012 15.7 3.1 71 3.6 0.0 6.6 9 0 0 9 9 9 0 SAB domain MAF_flag10 PF01973.18 EAX90078.1 - 0.023 14.4 8.0 0.39 10.4 0.5 3.3 1 1 2 4 4 4 0 Protein of unknown function DUF115 Vault PF01505.18 EAX90078.1 - 0.053 13.7 4.0 9.5 6.5 0.0 5.7 8 0 0 8 8 8 0 Major Vault Protein repeat domain PIP49_N PF14875.6 EAX90078.1 - 0.15 11.9 7.6 40 4.0 0.1 4.8 1 1 4 5 5 5 0 N-term cysteine-rich ER, FAM69 LEM PF03020.15 EAX90078.1 - 0.16 11.6 5.4 1.1e+02 2.4 0.0 6.3 9 0 0 9 9 9 0 LEM domain DUF520 PF04461.13 EAX90078.1 - 1.1 9.4 5.4 13 5.9 0.0 4.0 1 1 4 6 6 6 0 Protein of unknown function (DUF520) Phage_int_SAM_5 PF13102.6 EAX90079.1 - 0.0025 18.1 0.8 0.0025 18.1 0.8 1.9 2 0 0 2 2 2 1 Phage integrase SAM-like domain MT0933_antitox PF14013.6 EAX90079.1 - 0.047 14.0 1.6 0.047 14.0 1.6 2.0 2 0 0 2 2 2 0 MT0933-like antitoxin protein DUF4407 PF14362.6 EAX90079.1 - 2.2 7.5 11.4 2.8 7.2 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TP6A_N PF04406.14 EAX90080.1 - 9.4e-19 67.2 0.0 2.1e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Macro PF01661.21 EAX90080.1 - 0.14 12.2 0.3 0.37 10.8 0.1 1.7 2 0 0 2 2 2 0 Macro domain PSP PF04046.16 EAX90081.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90082.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90083.1 - 0.034 14.6 0.7 0.069 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ank PF00023.30 EAX90084.1 - 3.9e-117 378.1 39.1 5.8e-09 36.0 0.0 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.6 EAX90084.1 - 9.3e-114 370.5 49.5 1.2e-11 44.9 0.1 16.0 2 1 14 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90084.1 - 2e-99 324.3 58.7 6.7e-11 42.2 0.2 11.2 2 1 12 14 14 14 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90084.1 - 1.3e-98 323.8 58.6 1.8e-15 57.3 3.1 9.4 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90084.1 - 2.6e-91 288.5 37.0 1.9e-06 27.7 0.0 15.9 16 0 0 16 16 16 13 Ankyrin repeat DUF3447 PF11929.8 EAX90084.1 - 3.1e-38 129.6 5.6 3.1e-38 129.6 5.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) LolA PF03548.15 EAX90084.1 - 2.1e-07 30.8 0.9 4.4 7.0 0.0 6.1 3 2 3 7 7 7 1 Outer membrane lipoprotein carrier protein LolA MetallophosN PF16371.5 EAX90084.1 - 7.6e-07 29.3 0.0 2.6 8.4 0.0 6.2 2 2 6 8 8 8 1 N terminal of Calcineurin-like phosphoesterase ThiS-like PF14453.6 EAX90084.1 - 1.2e-05 25.3 28.2 1e+02 3.1 0.1 12.6 1 1 12 13 13 13 0 ThiS-like ubiquitin AnkUBD PF18418.1 EAX90084.1 - 0.00022 21.3 0.0 27 5.0 0.0 4.5 4 0 0 4 4 4 0 Ankyrin ubiquitin-binding domain PH_8 PF15409.6 EAX90084.1 - 0.00038 20.7 6.1 93 3.4 0.0 8.4 2 2 8 11 11 11 0 Pleckstrin homology domain Phage_G PF02306.15 EAX90084.1 - 0.0017 18.1 16.2 30 4.3 0.3 7.2 2 2 6 8 8 8 0 Major spike protein (G protein) CCG PF02754.16 EAX90084.1 - 0.018 15.3 2.6 1.8e+02 2.4 0.0 5.1 2 2 2 5 5 5 0 Cysteine-rich domain PUB_1 PF18486.1 EAX90084.1 - 0.084 12.7 1.1 2.3e+02 1.7 0.0 4.2 4 0 0 4 4 4 0 PNGase/UBA- or UBX-containing domain Staphylokinase PF02821.16 EAX90084.1 - 0.14 12.6 7.6 2.8e+02 1.9 0.1 7.4 1 1 8 9 9 9 0 Staphylokinase/Streptokinase family Defensin_3 PF08131.11 EAX90084.1 - 0.95 9.7 6.2 2.1e+02 2.2 0.1 4.6 4 0 0 4 4 4 0 Defensin-like peptide family RNA_pol_Rpb1_5 PF04998.17 EAX90086.1 - 1.3e-18 67.4 4.6 2e-18 66.8 4.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 CobT PF06213.12 EAX90086.1 - 0.00067 19.1 7.4 0.00094 18.7 7.4 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DDHD PF02862.17 EAX90086.1 - 0.015 15.5 0.8 0.018 15.2 0.8 1.2 1 0 0 1 1 1 0 DDHD domain FmiP_Thoc5 PF09766.9 EAX90086.1 - 0.041 13.2 8.8 0.071 12.4 8.8 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 GPAT_N PF14829.6 EAX90086.1 - 0.043 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Connexin PF00029.19 EAX90086.1 - 0.053 13.3 4.1 0.082 12.6 4.1 1.2 1 0 0 1 1 1 0 Connexin DUF4615 PF15393.6 EAX90086.1 - 0.092 13.3 8.8 0.15 12.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) LIP1 PF15904.5 EAX90086.1 - 0.15 12.5 0.1 17 5.8 0.0 2.4 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 NOA36 PF06524.12 EAX90086.1 - 0.4 10.0 9.3 0.66 9.2 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.10 EAX90086.1 - 0.59 10.4 13.1 0.94 9.8 13.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EAX90086.1 - 1.1 7.5 10.2 1.4 7.1 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Ferlin_C PF16165.5 EAX90086.1 - 1.4 8.9 6.6 2.4 8.1 6.6 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Presenilin PF01080.17 EAX90086.1 - 1.7 7.3 7.8 2.3 6.9 7.8 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 EAX90086.1 - 3.9 7.5 6.9 6.2 6.9 6.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Ureide_permease PF07168.11 EAX90086.1 - 4.5 5.9 9.2 48 2.6 9.3 2.0 1 1 0 1 1 1 0 Ureide permease MDM10 PF12519.8 EAX90086.1 - 7.5 5.3 8.6 12 4.6 8.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RNA_pol_Rpb1_1 PF04997.12 EAX90087.1 - 2.3e-33 115.9 0.7 2.9e-33 115.5 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 LRR_5 PF13306.6 EAX90089.1 - 2.2e-33 115.0 31.7 2.1e-16 60.1 7.6 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90089.1 - 2.1e-07 30.6 0.7 5.7 6.8 0.0 5.5 3 1 2 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 EAX90090.1 - 8.2e-100 329.7 140.1 6.2e-21 74.7 6.4 9.5 3 2 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90090.1 - 3.1e-10 39.6 25.5 0.56 10.0 0.1 13.1 11 5 4 15 15 15 5 Leucine rich repeat Beta_helix PF13229.6 EAX90091.1 - 2.3e-50 170.5 111.1 1.4e-14 54.2 1.5 5.7 1 1 6 7 7 7 7 Right handed beta helix region NosD PF05048.13 EAX90091.1 - 1.1e-23 83.8 49.5 4.4e-08 32.7 7.9 5.1 1 1 3 5 5 5 5 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EAX90091.1 - 1.2e-09 38.3 44.3 0.00017 21.5 8.5 6.7 2 2 1 5 5 5 5 Pectate lyase superfamily protein Pectinesterase PF01095.19 EAX90091.1 - 0.00076 18.3 0.5 0.002 16.9 0.5 1.7 1 0 0 1 1 1 1 Pectinesterase PRCC PF10253.9 EAX90091.1 - 2.6 8.8 8.7 4.8 7.9 8.7 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting VASt PF16016.5 EAX90092.1 - 1.3e-05 25.7 0.6 7.8e-05 23.1 0.6 2.2 1 1 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain MH2 PF03166.14 EAX90092.1 - 0.0037 17.5 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 MH2 domain GRAM PF02893.20 EAX90092.1 - 0.008 16.1 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 GRAM domain CH_2 PF06294.11 EAX90093.1 - 4.8e-32 109.9 0.1 9.9e-32 108.9 0.1 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EAX90093.1 - 7.2e-13 48.2 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EAX90093.1 - 0.00025 21.2 0.6 0.00025 21.2 0.6 1.8 2 1 0 2 2 2 1 Calponin homology (CH) domain IMPa_helical PF18642.1 EAX90093.1 - 0.069 13.6 0.1 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain YyzF PF14116.6 EAX90093.1 - 0.1 12.6 0.8 0.23 11.5 0.8 1.5 1 0 0 1 1 1 0 YyzF-like protein Ank_2 PF12796.7 EAX90094.1 - 4.7e-35 120.0 12.1 2e-14 53.9 0.4 6.0 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90094.1 - 1.2e-27 95.6 2.6 1.4e-07 31.6 0.2 6.4 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX90094.1 - 1.1e-24 86.5 8.8 1.1e-08 35.4 0.2 8.3 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX90094.1 - 6.1e-21 73.9 10.3 0.025 15.0 0.1 7.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX90094.1 - 8.7e-19 65.7 13.6 0.00085 19.6 0.2 9.8 12 0 0 12 12 12 4 Ankyrin repeat DUF3447 PF11929.8 EAX90094.1 - 4.6e-10 39.3 16.2 8e-08 32.1 1.2 6.1 3 1 3 6 6 6 2 Domain of unknown function (DUF3447) ATP-synt PF00231.19 EAX90094.1 - 0.042 13.6 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 ATP synthase C2 PF00168.30 EAX90095.1 - 3.1e-13 49.9 0.0 7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain COPIIcoated_ERV PF07970.12 EAX90096.1 - 9.7e-37 127.0 0.1 1.1e-36 126.8 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Nup54_57_C PF18570.1 EAX90096.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Sec1 PF00995.23 EAX90097.1 - 2.8e-53 182.0 0.0 3.2e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4625 PF15418.6 EAX90098.1 - 3.1e-08 34.0 2.9 0.022 15.0 0.0 4.3 1 1 1 3 3 3 3 Domain of unknown function (DUF4625) DUF4469 PF14734.6 EAX90098.1 - 0.0018 18.4 0.0 1.3 9.2 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4469) with IG-like fold DUF2326 PF10088.9 EAX90098.1 - 0.0019 17.9 0.7 0.95 9.2 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2326) Alph_Pro_TM PF09608.10 EAX90098.1 - 0.088 12.6 0.0 31 4.3 0.0 3.3 4 0 0 4 4 4 0 Putative transmembrane protein (Alph_Pro_TM) Spt20 PF12090.8 EAX90099.1 - 2.5e-26 92.7 5.2 9.5e-17 61.4 3.3 2.4 1 1 1 2 2 2 2 Spt20 family DUF2089 PF09862.9 EAX90100.1 - 0.032 14.3 1.8 0.39 10.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) TPR_8 PF13181.6 EAX90102.1 - 0.037 14.2 0.7 38 4.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX90102.1 - 0.083 13.0 0.1 23 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX90103.1 - 2.8e-25 89.2 0.0 3.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90103.1 - 1e-12 47.9 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX90103.1 - 5.7e-09 35.2 0.0 8.8e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX90103.1 - 0.00016 21.7 0.0 0.00049 20.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX90103.1 - 0.0054 16.3 0.3 0.01 15.5 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EAX90103.1 - 0.04 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EAX90103.1 - 0.091 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4838 PF16126.5 EAX90104.1 - 2.2e-37 128.9 6.0 6e-37 127.4 6.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) DUF5305 PF17231.2 EAX90104.1 - 0.00045 19.7 0.7 0.00096 18.6 0.7 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Podoplanin PF05808.11 EAX90104.1 - 0.005 17.0 0.7 0.01 16.0 0.7 1.4 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 EAX90104.1 - 0.013 15.9 1.0 0.033 14.6 0.1 2.2 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 EAX90104.1 - 0.029 13.2 0.1 0.051 12.4 0.1 1.3 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 EAX90104.1 - 0.066 13.2 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Mid2 PF04478.12 EAX90104.1 - 0.23 11.3 2.5 0.32 10.8 0.8 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 EAX90104.1 - 0.53 10.2 2.4 0.53 10.2 0.9 1.8 2 0 0 2 2 2 0 Syndecan domain DUF4838 PF16126.5 EAX90105.1 - 3.6e-25 88.8 0.2 5.2e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Glyco_hydro_67N PF03648.14 EAX90105.1 - 1.6e-08 34.9 0.0 2.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Peptidase_M8 PF01457.16 EAX90106.1 - 1.4e-32 113.1 0.0 2.8e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Shisa PF13908.6 EAX90106.1 - 5.7e-06 26.7 0.4 9.5e-06 26.0 0.4 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EAX90106.1 - 0.002 18.0 0.7 0.0041 17.0 0.7 1.4 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 EAX90106.1 - 0.0053 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) PRIMA1 PF16101.5 EAX90106.1 - 0.047 13.7 1.4 0.087 12.9 1.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ETRAMP PF09716.10 EAX90106.1 - 0.048 13.7 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMEM52 PF14979.6 EAX90106.1 - 0.095 12.6 0.8 0.16 11.9 0.8 1.3 1 0 0 1 1 1 0 Transmembrane 52 Insulin_TMD PF17870.1 EAX90106.1 - 0.28 11.3 2.9 0.64 10.1 2.9 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 EAX90106.1 - 3.3 8.7 5.9 1.1 10.2 2.4 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM108 PF15759.5 EAX90106.1 - 3.8 6.4 4.7 5.4 5.9 4.7 1.1 1 0 0 1 1 1 0 TMEM108 family ECSCR PF15820.5 EAX90106.1 - 5.7 6.8 7.6 3.1 7.7 5.1 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Ank_4 PF13637.6 EAX90107.1 - 7.5e-34 115.7 6.1 1.4e-07 31.9 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX90107.1 - 6.4e-31 105.4 7.5 1.2e-07 31.9 0.0 5.9 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX90107.1 - 2.7e-25 85.7 2.9 5.5e-05 23.2 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 EAX90107.1 - 3.5e-25 88.4 2.4 7.9e-15 55.2 0.6 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90107.1 - 4e-21 74.8 4.9 1.5e-06 28.3 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90108.1 - 2.3e-24 85.1 4.3 2.3e-24 85.1 4.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX90108.1 - 0.031 14.9 0.0 0.7 10.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) GST_C_3 PF14497.6 EAX90109.1 - 0.03 14.5 0.2 0.11 12.6 0.2 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CsiV PF10972.8 EAX90110.1 - 0.0082 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Peptidoglycan-binding protein, CsiV XPG_I PF00867.18 EAX90110.1 - 0.019 15.3 2.0 0.039 14.3 0.0 2.4 2 0 0 2 2 2 0 XPG I-region cNMP_binding PF00027.29 EAX90111.1 - 5.5e-06 26.4 0.0 0.69 10.0 0.0 3.7 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ank_2 PF12796.7 EAX90112.1 - 4.7e-49 164.9 46.0 1.5e-18 67.1 2.9 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90112.1 - 4.3e-38 128.1 16.9 4.5e-08 33.2 0.1 8.1 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 EAX90112.1 - 4.9e-37 125.7 5.1 4.9e-37 125.7 5.1 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX90112.1 - 5e-33 113.0 14.3 1.3e-11 44.8 0.1 7.3 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90112.1 - 5.8e-27 93.4 28.3 2.3e-09 37.3 2.2 6.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90112.1 - 3e-25 85.5 15.9 0.00017 21.7 0.1 9.1 9 0 0 9 9 9 5 Ankyrin repeat PH_8 PF15409.6 EAX90112.1 - 0.038 14.3 0.1 25 5.2 0.0 3.7 2 1 0 3 3 3 0 Pleckstrin homology domain eRF1_1 PF03463.15 EAX90112.1 - 0.17 11.9 1.0 4.5 7.3 0.1 2.9 2 1 0 2 2 2 0 eRF1 domain 1 Ank PF00023.30 EAX90113.1 - 1e-22 79.5 3.9 7.2e-09 35.7 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX90113.1 - 1.3e-21 76.7 0.9 1.9e-10 41.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90113.1 - 2.8e-20 72.7 2.0 7.6e-20 71.3 2.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90113.1 - 3.6e-17 60.7 0.5 1.7e-06 27.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX90113.1 - 5e-16 58.5 2.3 3.6e-12 46.3 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX90113.1 - 0.011 15.5 0.1 0.034 13.9 0.0 1.8 2 1 0 2 2 2 0 Colon cancer-associated protein Mic1-like Ribosomal_S6 PF01250.17 EAX90113.1 - 0.024 14.9 0.0 0.57 10.5 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S6 Thioredoxin_6 PF13848.6 EAX90114.1 - 0.028 14.3 2.1 0.21 11.5 0.1 2.9 3 1 0 3 3 3 0 Thioredoxin-like domain Y_Y_Y PF07495.13 EAX90116.1 - 1.6e-07 31.2 25.7 0.6 10.1 0.0 12.2 15 0 0 15 15 15 3 Y_Y_Y domain DUF4832 PF16116.5 EAX90116.1 - 2.2e-07 31.0 0.9 2.3 8.0 0.0 5.8 6 0 0 6 6 6 2 Domain of unknown function (DUF4832) DUF4625 PF15418.6 EAX90116.1 - 6e-07 29.8 31.2 0.046 14.0 0.2 12.5 13 2 1 14 14 14 3 Domain of unknown function (DUF4625) fn3_3 PF14686.6 EAX90116.1 - 0.0018 18.0 0.5 0.41 10.5 0.1 4.2 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II Big_3_4 PF13754.6 EAX90116.1 - 0.0027 17.4 0.2 8.2 6.2 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function Arm-DNA-bind_5 PF17293.2 EAX90116.1 - 0.013 15.9 1.7 0.13 12.7 0.0 3.4 3 0 0 3 3 3 0 Arm DNA-binding domain bMG10 PF17973.1 EAX90116.1 - 0.028 14.6 0.1 0.43 10.8 0.0 2.9 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain He_PIG PF05345.12 EAX90116.1 - 0.85 9.9 11.4 28 5.0 0.4 6.2 6 0 0 6 6 6 0 Putative Ig domain rRNA_processing PF08524.11 EAX90117.1 - 1.4e-05 25.2 13.4 1.8e-05 24.8 13.4 1.3 1 1 0 1 1 1 1 rRNA processing MCR_beta_N PF02783.15 EAX90117.1 - 0.0099 15.5 0.5 0.01 15.5 0.5 1.1 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain PHM7_cyt PF14703.6 EAX90117.1 - 0.024 14.9 5.7 0.029 14.6 5.7 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Pex2_Pex12 PF04757.14 EAX90117.1 - 0.11 12.0 0.6 0.14 11.7 0.6 1.1 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Pacs-1 PF10254.9 EAX90117.1 - 0.21 10.5 4.1 0.21 10.5 4.1 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein CemA PF03040.14 EAX90117.1 - 0.57 10.1 4.9 0.71 9.8 4.9 1.2 1 0 0 1 1 1 0 CemA family Ank_2 PF12796.7 EAX90118.1 - 1.9e-49 166.2 10.7 2.6e-11 44.0 0.7 6.5 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90118.1 - 1.1e-33 115.2 2.2 2.6e-06 27.9 0.1 8.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90118.1 - 1.8e-29 98.5 1.4 0.0027 18.0 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EAX90118.1 - 5e-28 96.8 5.2 2.2e-05 24.7 0.2 9.2 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX90118.1 - 9.2e-21 73.3 0.1 0.014 15.8 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 EAX90118.1 - 5.1e-13 48.8 6.0 1.1e-05 25.3 0.0 6.1 5 1 1 6 6 6 2 Domain of unknown function (DUF3447) DUF438 PF04282.13 EAX90118.1 - 0.00067 19.6 0.4 0.7 9.9 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF438) DUF563 PF04577.14 EAX90119.1 - 2e-35 122.9 0.5 4.7e-35 121.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Ank_2 PF12796.7 EAX90120.1 - 1.3e-83 275.6 3.4 1.3e-13 51.4 0.0 9.3 2 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90120.1 - 5.7e-68 216.8 15.8 3.2e-05 24.0 0.1 16.3 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.6 EAX90120.1 - 3.4e-66 218.8 18.9 7.9e-09 35.9 0.0 14.9 4 2 12 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90120.1 - 2.5e-59 196.6 14.8 2.4e-08 34.1 0.1 11.3 5 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX90120.1 - 8.2e-56 184.1 17.3 5.2e-05 23.5 0.1 15.5 15 0 0 15 15 15 11 Ankyrin repeat DUF3447 PF11929.8 EAX90120.1 - 0.00024 21.0 0.2 0.13 12.3 0.0 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Elicitin PF00964.17 EAX90120.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Elicitin Metallophos PF00149.28 EAX90122.1 - 4.8e-31 108.9 0.5 4.8e-31 108.9 0.5 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX90122.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.31 EAX90123.1 - 2e-15 57.0 0.0 5.8e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EAX90124.1 - 1.4e-12 47.8 2.5 1.7e-12 47.5 1.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF4272 PF14094.6 EAX90124.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) APAF1_C PF17908.1 EAX90125.1 - 0.22 11.5 5.4 1.4 8.9 0.8 2.6 1 1 0 2 2 2 0 APAF-1 helical domain Lung_7-TM_R PF06814.13 EAX90126.1 - 9.2e-05 21.8 22.1 0.00015 21.1 22.1 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EAX90126.1 - 0.00052 19.5 15.1 0.00052 19.5 15.1 2.3 1 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Gly_rich PF12810.7 EAX90127.1 - 6.5e-43 147.4 54.7 1.4e-42 146.3 54.7 1.5 1 0 0 1 1 1 1 Glycine rich protein DUF4625 PF15418.6 EAX90127.1 - 0.24 11.6 2.0 0.27 11.5 0.3 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) Gly_rich PF12810.7 EAX90128.1 - 1.8e-20 73.9 40.1 4.5e-20 72.6 40.1 1.6 1 0 0 1 1 1 1 Glycine rich protein DUF4625 PF15418.6 EAX90128.1 - 0.93 9.7 4.2 0.85 9.9 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) Aminotran_1_2 PF00155.21 EAX90129.1 - 1.5e-49 169.1 0.0 1.9e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EAX90129.1 - 0.00076 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 EAX90129.1 - 0.008 14.9 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III IBP39 PF11422.8 EAX90130.1 - 1e-65 220.9 2.3 1.4e-65 220.4 2.3 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 EAX90130.1 - 3.6e-19 69.1 0.0 7.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4457 PF14652.6 EAX90131.1 - 4.3e-16 59.1 1.3 7e-06 25.5 0.2 3.6 1 1 1 3 3 3 3 Domain of unknown function (DUF4457) ubiquitin PF00240.23 EAX90132.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF695 PF05117.12 EAX90132.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF695) DUF4106 PF13388.6 EAX90133.1 - 1.1e-95 321.4 5.4 2e-95 320.5 5.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Ribosomal_L18_c PF14204.6 EAX90133.1 - 5.2 8.1 12.0 9.3 7.3 3.0 4.1 3 1 0 3 3 3 0 Ribosomal L18 C-terminal region GPS2_interact PF15784.5 EAX90135.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX90135.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TALPID3 PF15324.6 EAX90136.1 - 1.6 6.3 10.7 2 6.0 10.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target FAS_N PF17828.1 EAX90137.1 - 0.065 13.2 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX90138.1 - 0.02 15.3 0.7 0.027 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX90138.1 - 1.6 7.7 4.0 1.7 7.6 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX90138.1 - 3.8 8.2 6.6 8.4 7.1 6.6 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX90138.1 - 4.1 7.4 7.6 4.4 7.3 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX90139.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX90139.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Lipase_3 PF01764.25 EAX90140.1 - 2e-19 69.9 0.0 3.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EAX90140.1 - 0.0021 17.6 0.0 0.0045 16.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EAX90140.1 - 0.035 14.7 0.0 0.037 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family CLP1_P PF16575.5 EAX90142.1 - 3.9e-23 82.2 0.0 5.9e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 EAX90142.1 - 0.019 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX90142.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAX90142.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 EAX90143.1 - 6e-05 22.6 2.9 6.3e-05 22.6 1.8 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX90143.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 U3snoRNP10 PF12397.8 EAX90145.1 - 3 8.2 7.4 1.6 9.1 2.2 3.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 NB PF04159.13 EAX90146.1 - 0.0031 17.5 2.9 0.46 10.5 0.1 3.0 2 0 0 2 2 2 2 NB glycoprotein Myb_DNA-binding PF00249.31 EAX90147.1 - 8.8e-22 77.0 1.3 7.5e-12 45.3 1.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90147.1 - 4.4e-20 71.7 4.2 4.8e-13 49.1 0.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90147.1 - 1.2e-05 25.3 0.9 0.0082 16.2 0.0 2.9 1 1 1 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EAX90147.1 - 0.022 15.1 2.3 0.41 11.0 0.5 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 EAX90147.1 - 0.027 14.8 4.4 0.03 14.7 1.4 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EAX90148.1 - 1.3e-62 211.6 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90148.1 - 5.8e-37 127.4 0.0 7.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX90148.1 - 0.0022 18.5 0.2 0.0049 17.4 0.2 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 EAX90148.1 - 0.0079 15.2 0.1 0.019 13.9 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX90148.1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like TypeIII_RM_meth PF12564.8 EAX90148.1 - 0.027 14.6 0.1 0.085 13.0 0.1 1.9 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit FTA2 PF13095.6 EAX90148.1 - 0.033 13.8 0.8 7.4 6.1 0.4 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NT-C2 PF10358.9 EAX90149.1 - 4.3e-20 71.9 0.3 9.2e-20 70.8 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF1433 PF07252.11 EAX90150.1 - 0.069 13.4 0.1 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) T5orf172 PF10544.9 EAX90151.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX90152.1 - 1.3e-07 31.3 1.8 1.4e-07 31.2 1.8 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX90152.1 - 0.0028 17.3 0.1 0.0034 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX90152.1 - 0.038 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX90152.1 - 0.043 13.5 0.1 0.18 11.6 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX90152.1 - 0.057 13.6 4.7 3.6 7.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF3783 PF12646.7 EAX90152.1 - 0.15 12.0 1.3 0.93 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3783) DUF2897 PF11446.8 EAX90153.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX90154.1 - 1.5e-49 167.6 5.9 1.6e-49 167.5 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX90155.1 - 2.9e-94 309.8 15.5 2.7e-19 69.5 0.3 6.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90155.1 - 1.5e-63 210.4 10.7 1.9e-10 41.0 0.0 9.2 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 EAX90155.1 - 6.3e-62 203.5 5.6 1.2e-05 25.5 0.1 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAX90155.1 - 4.9e-54 179.7 10.4 2.2e-07 31.0 0.1 11.5 1 1 11 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90155.1 - 6.4e-51 164.4 1.8 0.015 15.8 0.0 12.1 12 0 0 12 12 11 11 Ankyrin repeat KASH_CCD PF14662.6 EAX90155.1 - 8.1e-08 32.3 39.4 6.8e-07 29.3 18.6 6.4 1 1 4 6 6 6 3 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 EAX90155.1 - 5.1e-05 23.4 17.3 5.1e-05 23.4 17.3 7.0 3 3 4 7 7 5 2 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EAX90155.1 - 0.0007 18.6 24.5 0.0007 18.6 24.5 5.4 1 1 4 5 5 4 2 Spc7 kinetochore protein HALZ PF02183.18 EAX90155.1 - 0.00085 19.5 88.4 0.016 15.4 1.6 13.1 8 3 7 15 15 15 6 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 EAX90155.1 - 0.0013 18.8 20.3 0.0013 18.8 20.3 6.4 2 2 4 6 6 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EAX90155.1 - 0.0024 18.1 12.0 0.0024 18.1 12.0 6.6 3 2 1 5 5 4 3 Autophagy protein 16 (ATG16) TLE_N PF03920.15 EAX90155.1 - 0.0037 17.3 2.8 0.0037 17.3 2.8 5.9 4 2 1 5 5 5 1 Groucho/TLE N-terminal Q-rich domain Prp19 PF08606.11 EAX90155.1 - 0.0041 17.1 0.5 0.0041 17.1 0.5 6.8 6 2 1 7 7 7 2 Prp19/Pso4-like DivIC PF04977.15 EAX90155.1 - 0.0048 16.6 93.6 0.14 11.9 8.4 10.4 6 4 3 9 9 9 5 Septum formation initiator Cnn_1N PF07989.11 EAX90155.1 - 0.0049 17.0 14.5 0.0049 17.0 14.5 9.6 4 3 5 9 9 9 3 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EAX90155.1 - 0.011 16.3 17.8 0.011 16.3 17.8 7.7 1 1 5 7 7 5 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EAX90155.1 - 0.88 9.7 124.8 0.31 11.1 7.4 12.6 5 3 7 12 12 12 0 bZIP transcription factor PilJ PF13675.6 EAX90155.1 - 1.8 8.6 5.1 4.6 7.3 0.1 3.4 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2590 PF10761.9 EAX90155.1 - 6 7.1 7.7 1.8 8.8 0.4 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF2590) GPS2_interact PF15784.5 EAX90158.1 - 0.049 14.1 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain zf-C2H2_2 PF12756.7 EAX90159.1 - 1.9e-35 121.2 20.0 3.1e-22 78.8 1.9 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAX90159.1 - 0.00024 21.7 29.7 0.0097 16.7 1.6 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger DIM1 PF02966.16 EAX90159.1 - 0.055 13.2 1.5 6.3 6.6 0.2 2.8 2 1 0 2 2 2 0 Mitosis protein DIM1 zf-LYAR PF08790.11 EAX90159.1 - 0.12 12.3 5.8 5.2 7.1 1.5 3.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Vps39_2 PF10367.9 EAX90159.1 - 0.53 10.8 0.0 0.53 10.8 0.0 3.3 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_3rep PF18868.1 EAX90159.1 - 1.8 9.3 16.1 0.93 10.2 1.1 3.9 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Endonuclease_7 PF02945.15 EAX90159.1 - 4.9 7.2 14.6 1 9.3 0.5 4.3 5 0 0 5 5 5 0 Recombination endonuclease VII Pkinase PF00069.25 EAX90161.1 - 3.9e-41 141.2 0.0 1.2e-39 136.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90161.1 - 5e-22 78.4 0.0 1.2e-21 77.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX90161.1 - 6.3e-08 31.8 1.7 9.3e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAX90161.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX90161.1 - 0.0079 15.8 0.8 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EAX90161.1 - 0.087 12.7 0.1 0.42 10.5 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family HAUS-augmin3 PF14932.6 EAX90164.1 - 0.072 12.7 1.2 0.15 11.6 1.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AbiJ_NTD4 PF18863.1 EAX90166.1 - 0.085 13.3 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 DUF641 PF04859.12 EAX90167.1 - 0.064 13.6 1.9 0.092 13.1 1.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 EAX90167.1 - 0.17 12.1 4.3 0.26 11.5 4.3 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EAX90167.1 - 0.46 10.6 5.5 2.6 8.2 0.0 2.5 1 1 1 2 2 2 0 bZIP transcription factor Myb_DNA-binding PF00249.31 EAX90169.1 - 3e-25 88.1 0.4 6.7e-14 51.8 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90169.1 - 9.1e-18 64.3 0.1 5.8e-12 45.7 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX90169.1 - 0.31 10.9 2.7 4.6 7.2 0.2 2.8 1 1 2 3 3 3 0 Myb DNA-binding like Pkinase PF00069.25 EAX90170.1 - 1.2e-58 198.6 0.0 2.5e-58 197.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90170.1 - 2.5e-57 194.1 0.0 4.1e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX90170.1 - 3.5e-06 26.1 0.1 5.8e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX90170.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX90170.1 - 0.0051 16.4 0.3 0.013 15.1 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAX90170.1 - 0.0067 15.8 0.0 0.06 12.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Rogdi_lz PF10259.9 EAX90170.1 - 0.018 14.5 0.2 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Haspin_kinase PF12330.8 EAX90170.1 - 0.05 12.5 0.1 0.12 11.2 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EAX90170.1 - 0.15 11.9 0.1 1.8 8.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.25 EAX90171.1 - 0.00013 22.0 0.4 0.00027 21.0 0.4 1.5 1 0 0 1 1 1 1 F5/8 type C domain BTB PF00651.31 EAX90171.1 - 0.031 14.5 1.3 0.056 13.7 0.2 1.9 2 0 0 2 2 2 0 BTB/POZ domain BACK PF07707.15 EAX90171.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch E1-E2_ATPase PF00122.20 EAX90173.1 - 0.00025 20.6 0.1 0.00026 20.6 0.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase Orf78 PF06024.12 EAX90173.1 - 0.00032 21.0 0.4 0.00032 20.9 0.4 1.1 1 0 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 EAX90173.1 - 0.011 14.5 0.1 0.011 14.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CCSMST1 PF15013.6 EAX90173.1 - 0.025 14.8 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 CCSMST1 family DUF4328 PF14219.6 EAX90173.1 - 0.028 14.0 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Sigma_reg_N PF13800.6 EAX90173.1 - 0.073 13.4 3.6 0.1 12.9 3.6 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal FA_desaturase PF00487.24 EAX90173.1 - 0.095 12.5 0.1 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF5113 PF17140.4 EAX90173.1 - 0.095 12.5 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) DUF4448 PF14610.6 EAX90173.1 - 0.1 12.4 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AMA-1 PF02430.15 EAX90173.1 - 0.1 11.5 0.5 0.1 11.5 0.5 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 Syndecan PF01034.20 EAX90173.1 - 0.2 11.6 2.6 0.14 12.1 1.0 1.6 2 0 0 2 2 2 0 Syndecan domain DUF2116 PF09889.9 EAX90173.1 - 0.31 11.1 3.4 0.49 10.4 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) VSP PF03302.13 EAX90173.1 - 0.46 9.3 3.0 0.54 9.0 3.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Orf78 PF06024.12 EAX90174.1 - 0.00023 21.4 0.2 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 1 Orf78 (ac78) VSP PF03302.13 EAX90174.1 - 0.00064 18.7 2.2 0.0011 17.9 2.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3377 PF11857.8 EAX90174.1 - 0.00095 19.0 0.2 0.0036 17.2 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) RIFIN PF02009.16 EAX90174.1 - 0.0025 17.8 2.9 0.0025 17.8 2.9 1.8 1 1 1 2 2 2 1 Rifin Podoplanin PF05808.11 EAX90174.1 - 0.0052 16.9 2.9 0.0058 16.7 0.8 2.1 2 0 0 2 2 2 1 Podoplanin DUF4690 PF15756.5 EAX90174.1 - 0.0058 17.2 0.1 0.034 14.7 0.0 2.3 2 0 0 2 2 2 1 Small Novel Rich in Cartilage DUF2207 PF09972.9 EAX90174.1 - 0.0073 15.1 0.3 0.019 13.7 0.0 1.8 2 1 0 2 2 2 1 Predicted membrane protein (DUF2207) Shisa PF13908.6 EAX90174.1 - 0.0077 16.5 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Stevor PF17410.2 EAX90174.1 - 0.01 15.4 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 EAX90174.1 - 0.011 15.6 0.3 0.045 13.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3149 PF11346.8 EAX90174.1 - 0.012 15.2 4.4 0.032 13.8 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TMEM154 PF15102.6 EAX90174.1 - 0.036 14.0 0.2 0.098 12.6 0.2 1.7 1 0 0 1 1 1 0 TMEM154 protein family ASFV_J13L PF05568.11 EAX90174.1 - 0.04 13.7 1.1 0.1 12.4 1.1 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein m04gp34like PF12216.8 EAX90174.1 - 0.049 13.2 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Immune evasion protein 7TM_GPCR_Srv PF10323.9 EAX90174.1 - 0.052 12.9 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv CCSMST1 PF15013.6 EAX90174.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 CCSMST1 family LRRC37AB_C PF14914.6 EAX90174.1 - 0.1 12.5 0.3 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Syndecan PF01034.20 EAX90174.1 - 0.16 11.9 2.0 0.42 10.6 2.0 1.7 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EAX90174.1 - 0.21 12.5 1.5 0.64 10.9 1.5 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAX90174.1 - 1.1 9.4 8.4 2.5 8.2 8.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment YebO PF13974.6 EAX90174.1 - 1.3 9.2 6.6 3.9 7.6 6.6 1.8 1 0 0 1 1 1 0 YebO-like protein FeoB_associated PF12669.7 EAX90174.1 - 1.8 9.0 5.2 5.4 7.5 5.2 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Vpu PF00558.19 EAX90174.1 - 2.1 8.2 3.9 5.5 6.8 3.9 1.6 1 0 0 1 1 1 0 Vpu protein Sigma_reg_N PF13800.6 EAX90174.1 - 2.2 8.6 4.7 2.5 8.4 1.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal LRR_5 PF13306.6 EAX90175.1 - 6.3e-95 313.9 141.9 6.9e-23 81.0 21.7 5.0 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90175.1 - 2.2e-17 62.5 27.7 0.0029 17.3 1.1 9.6 6 2 5 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 EAX90175.1 - 0.00016 22.0 41.3 2.4 8.7 0.2 9.8 6 3 3 9 9 9 3 Leucine Rich repeats (2 copies) Orf78 PF06024.12 EAX90175.1 - 0.00029 21.1 0.7 0.00076 19.7 0.7 1.7 1 0 0 1 1 1 1 Orf78 (ac78) Insulin_TMD PF17870.1 EAX90175.1 - 0.00044 20.3 3.3 0.00099 19.1 3.3 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EAX90175.1 - 0.0038 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4448 PF14610.6 EAX90175.1 - 0.017 14.9 0.3 0.038 13.8 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3377 PF11857.8 EAX90175.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ETRAMP PF09716.10 EAX90175.1 - 0.04 14.0 0.4 0.04 14.0 0.4 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 EAX90175.1 - 1.5 9.7 3.4 3.3 8.6 3.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RicinB_lectin_2 PF14200.6 EAX90176.1 - 9.3e-07 29.5 0.1 0.0062 17.2 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_16 PF00722.21 EAX90177.1 - 2.6e-06 27.0 0.5 3.1e-06 26.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAX90177.1 - 0.0055 15.2 0.3 0.0061 15.0 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EAX90178.1 - 1.7e-05 24.4 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAX90178.1 - 0.006 15.1 0.1 0.0066 14.9 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Trypan_PARP PF05887.11 EAX90179.1 - 0.059 13.3 9.3 0.12 12.4 9.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 EAX90179.1 - 6.6 5.1 10.4 10 4.5 10.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TMEM154 PF15102.6 EAX90181.1 - 2.3e-05 24.3 0.1 2.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 EAX90181.1 - 0.00027 21.2 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) Shisa PF13908.6 EAX90181.1 - 0.00035 20.9 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 EAX90181.1 - 0.0013 18.6 0.1 0.0016 18.4 0.1 1.1 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain YebO PF13974.6 EAX90181.1 - 0.0033 17.5 3.1 0.03 14.4 1.4 2.3 2 0 0 2 2 2 1 YebO-like protein DUF5305 PF17231.2 EAX90181.1 - 0.0046 16.4 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) ECSCR PF15820.5 EAX90181.1 - 0.0055 16.5 0.5 0.0081 16.0 0.5 1.4 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator VSP PF03302.13 EAX90181.1 - 0.0065 15.4 1.1 0.0076 15.1 1.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF5385 PF17359.2 EAX90181.1 - 0.0069 16.0 0.6 0.0069 16.0 0.6 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5385) DUF4577 PF15145.6 EAX90181.1 - 0.0093 16.0 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) DUF2207 PF09972.9 EAX90181.1 - 0.013 14.2 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Endomucin PF07010.12 EAX90181.1 - 0.016 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Endomucin CCSMST1 PF15013.6 EAX90181.1 - 0.017 15.2 1.8 0.028 14.6 1.8 1.6 1 1 0 1 1 1 0 CCSMST1 family EphA2_TM PF14575.6 EAX90181.1 - 0.019 15.9 1.8 0.026 15.4 0.6 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.11 EAX90181.1 - 0.02 14.9 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Stevor PF17410.2 EAX90181.1 - 0.023 14.2 2.4 0.031 13.8 2.4 1.3 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4366 PF14283.6 EAX90181.1 - 0.024 14.7 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.16 EAX90181.1 - 0.028 13.2 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3149 PF11346.8 EAX90181.1 - 0.029 14.0 3.0 0.058 13.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) RIFIN PF02009.16 EAX90181.1 - 0.033 14.1 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Rifin Rax2 PF12768.7 EAX90181.1 - 0.033 13.7 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 EAX90181.1 - 0.037 13.9 2.1 0.049 13.5 1.8 1.3 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 EAX90181.1 - 0.04 13.7 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3377 PF11857.8 EAX90181.1 - 0.045 13.7 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sigma_reg_N PF13800.6 EAX90181.1 - 0.046 14.0 0.2 0.081 13.2 0.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Insulin_TMD PF17870.1 EAX90181.1 - 0.049 13.7 5.5 0.077 13.1 5.5 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 EAX90181.1 - 0.062 13.2 1.4 0.12 12.3 1.4 1.5 1 0 0 1 1 1 0 Syndecan domain ABC2_membrane_2 PF12679.7 EAX90181.1 - 0.069 12.4 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PIRT PF15099.6 EAX90181.1 - 0.071 12.7 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Chordopox_A13L PF05961.11 EAX90181.1 - 0.1 12.9 2.1 0.11 12.8 0.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Vpu PF00558.19 EAX90181.1 - 1.7 8.5 9.4 0.18 11.6 1.6 2.4 3 0 0 3 3 2 0 Vpu protein SKG6 PF08693.10 EAX90181.1 - 3.6 7.1 13.6 6.6 6.2 13.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FeoB_associated PF12669.7 EAX90181.1 - 3.9 8.0 8.1 9.5 6.7 8.1 1.6 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ASFV_J13L PF05568.11 EAX90181.1 - 4.3 7.0 6.8 5.8 6.6 6.3 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein Gly_rich PF12810.7 EAX90183.1 - 1.2e-33 117.1 35.1 1.4e-33 116.9 35.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX90184.1 - 4.4e-21 75.9 24.3 5.2e-21 75.7 24.3 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF4107 PF13389.6 EAX90185.1 - 4.9e-72 241.4 3.7 7.4e-72 240.8 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX90187.1 - 0.0025 17.5 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX90188.1 - 8.6e-135 447.8 11.3 1.2e-134 447.3 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX90188.1 - 0.094 13.2 1.3 8.8 6.9 0.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GalP_UDP_transf PF01087.22 EAX90188.1 - 0.22 11.9 2.2 2.4 8.5 0.5 2.2 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF2408 PF10303.9 EAX90188.1 - 0.52 10.9 2.4 0.42 11.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX90189.1 - 7.4e-07 29.7 0.6 2.1e-06 28.2 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX90189.1 - 0.017 14.7 0.6 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX90189.1 - 0.047 13.5 0.4 0.29 11.0 0.1 2.2 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX90190.1 - 1.5e-43 147.2 0.9 2.8e-43 146.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX90190.1 - 0.0052 17.4 0.0 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX90191.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90191.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90191.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90191.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90191.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90191.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90191.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90191.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX90191.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90191.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90191.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX90191.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Centro_C10orf90 PF17730.1 EAX90192.1 - 0.0059 15.5 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Centrosomal C10orf90 Viral_P18 PF04521.13 EAX90192.1 - 0.081 12.7 0.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein NOA36 PF06524.12 EAX90193.1 - 8.4 5.6 9.1 10 5.3 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein WW PF00397.26 EAX90194.1 - 5.9e-08 32.7 0.6 1.1e-07 31.8 0.6 1.5 1 0 0 1 1 1 1 WW domain Sds3 PF08598.11 EAX90194.1 - 0.0033 17.4 12.6 0.0033 17.4 12.6 9.2 1 1 5 7 7 7 4 Sds3-like Apolipoprotein PF01442.18 EAX90194.1 - 0.29 11.0 148.7 0.049 13.5 35.6 5.9 2 2 4 6 6 6 0 Apolipoprotein A1/A4/E domain PKK PF12474.8 EAX90194.1 - 1.8 8.7 232.9 0.17 12.0 26.4 12.0 3 2 10 13 13 13 0 Polo kinase kinase Profilin PF00235.19 EAX90195.1 - 7.3e-13 48.9 0.4 8.6e-13 48.7 0.4 1.0 1 0 0 1 1 1 1 Profilin Erf4 PF10256.9 EAX90196.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.3 4 0 0 4 4 4 0 Golgin subfamily A member 7/ERF4 family TPH PF13868.6 EAX90197.1 - 1.9e-05 23.4 143.7 1.9e-05 23.4 143.7 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain V-set PF07686.17 EAX90197.1 - 0.76 10.0 3.1 1.3 9.2 0.2 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF4107 PF13389.6 EAX90198.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1731 PF08338.11 EAX90200.1 - 0.11 12.4 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Myb_DNA-binding PF00249.31 EAX90202.1 - 6.7e-31 106.2 4.5 6e-16 58.4 0.6 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90202.1 - 1.3e-22 79.8 0.2 9.1e-12 45.1 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90202.1 - 0.00075 19.5 0.0 0.26 11.3 0.1 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX90202.1 - 0.004 17.0 0.6 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like CBM65_1 PF18259.1 EAX90202.1 - 0.058 13.6 0.2 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Carbohydrate binding module 65 domain 1 Myb_DNA-bind_4 PF13837.6 EAX90202.1 - 0.18 12.2 6.5 0.3 11.5 2.0 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX90202.1 - 0.2 11.8 0.9 0.32 11.2 0.1 1.8 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PSP PF04046.16 EAX90203.1 - 0.057 13.3 0.5 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP Bystin PF05291.11 EAX90204.1 - 0.0067 15.8 0.1 0.0076 15.6 0.1 1.1 1 0 0 1 1 1 1 Bystin HSP90 PF00183.18 EAX90205.1 - 7.7e-41 140.6 21.0 1e-40 140.1 21.0 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EAX90205.1 - 2.4e-13 50.5 0.1 4.7e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAX90205.1 - 8.7e-10 38.6 0.0 8.7e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 EAX90205.1 - 0.058 13.5 10.7 0.094 12.8 10.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 EAX90205.1 - 0.064 13.5 11.1 0.11 12.8 11.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated HSP90 PF00183.18 EAX90206.1 - 1e-81 275.4 1.8 1.2e-81 275.2 1.8 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 EAX90206.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C34 PF05413.11 EAX90206.1 - 0.32 11.3 2.3 1.6 9.0 0.1 2.5 1 1 1 2 2 2 0 Putative closterovirus papain-like endopeptidase Rad51 PF08423.11 EAX90207.1 - 9.6e-115 382.2 0.1 1.2e-114 381.8 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EAX90207.1 - 3.4e-12 46.4 0.1 4.9e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EAX90207.1 - 8e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EAX90207.1 - 3.6e-07 30.7 1.7 4e-06 27.3 1.7 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EAX90207.1 - 3.8e-06 26.4 0.4 6.8e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 KaiC AAA PF00004.29 EAX90207.1 - 4.9e-05 23.8 0.0 0.00018 22.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAX90207.1 - 0.00024 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EAX90207.1 - 0.0023 17.3 2.4 0.036 13.4 0.1 2.9 2 1 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EAX90207.1 - 0.042 14.1 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3958 PF13125.6 EAX90207.1 - 0.44 10.8 2.8 0.4 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Glyco_hydro_31 PF01055.26 EAX90208.1 - 2.2e-69 234.7 3.8 2.7e-69 234.5 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 EAX90208.1 - 7.9e-05 22.9 0.1 0.00023 21.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) VSP PF03302.13 EAX90208.1 - 0.0022 16.9 1.3 0.0029 16.5 1.3 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Orf78 PF06024.12 EAX90208.1 - 0.0022 18.3 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) DUF4448 PF14610.6 EAX90208.1 - 0.0038 17.0 0.1 0.0079 16.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 EAX90208.1 - 0.038 12.8 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless EptA_B_N PF08019.12 EAX90208.1 - 0.12 12.3 0.2 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB SKG6 PF08693.10 EAX90208.1 - 0.13 11.7 6.0 0.25 10.8 6.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_31 PF01055.26 EAX90209.1 - 3.2e-35 122.2 0.3 2.4e-34 119.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Ribosomal_L11_N PF03946.14 EAX90210.1 - 7.9e-19 67.3 1.2 1.3e-18 66.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EAX90210.1 - 1.5e-13 51.0 0.2 1.5e-13 51.0 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF4071 PF13281.6 EAX90211.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Anophelin PF10731.9 EAX90212.1 - 0.038 13.8 1.3 0.051 13.4 1.3 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Pkinase PF00069.25 EAX90213.1 - 1.5e-58 198.2 0.1 1.8e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90213.1 - 9.4e-31 107.0 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX90213.1 - 1.9e-07 30.7 0.0 4.2e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX90213.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX90213.1 - 0.016 14.3 0.8 0.037 13.1 0.4 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAX90213.1 - 0.055 12.2 0.0 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 EAX90214.1 - 1.2e-55 188.8 0.1 1.5e-55 188.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90214.1 - 7e-33 114.0 0.0 8.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX90214.1 - 6.9e-08 32.1 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX90214.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX90214.1 - 0.013 15.1 0.2 0.033 13.8 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF4108 PF13390.6 EAX90215.1 - 2e-72 241.8 11.6 2.3e-72 241.6 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ras PF00071.22 EAX90216.1 - 8.5e-38 129.5 0.0 9.9e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90216.1 - 7.4e-30 103.6 0.0 1.1e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90216.1 - 4.9e-11 42.4 0.0 5.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX90216.1 - 4.1e-09 36.6 0.1 0.0012 18.8 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX90216.1 - 1.3e-06 28.1 0.0 1.2e-05 25.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX90216.1 - 3.3e-06 27.1 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX90216.1 - 3.2e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX90216.1 - 0.0002 21.1 0.4 0.0034 17.2 0.4 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EAX90216.1 - 0.00069 19.5 0.2 0.003 17.4 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EAX90216.1 - 0.0035 16.9 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_7 PF12775.7 EAX90216.1 - 0.0056 16.2 0.1 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 P-loop containing dynein motor region SRPRB PF09439.10 EAX90216.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EAX90216.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 EAX90216.1 - 0.049 14.0 0.0 0.065 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EAX90216.1 - 0.12 12.9 0.4 0.14 12.6 0.4 1.4 1 1 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 EAX90217.1 - 5.9e-22 78.7 0.1 1.2e-21 77.6 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX90217.1 - 2.4e-10 40.0 19.5 2.4e-10 40.0 19.5 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAX90217.1 - 1.2e-06 28.6 2.9 0.0017 18.2 0.0 3.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EAX90217.1 - 0.017 15.5 0.3 0.048 14.1 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX90217.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EAX90217.1 - 0.03 14.6 0.0 0.18 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 EAX90217.1 - 0.066 12.6 0.8 0.68 9.3 0.8 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 EAX90217.1 - 0.12 12.4 0.5 1 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAX90217.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EAX90217.1 - 0.13 11.5 0.2 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EAX90217.1 - 0.21 10.7 0.8 0.33 10.1 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EAX90217.1 - 7.6 7.0 10.1 0.089 13.3 1.3 2.3 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EAX90218.1 - 1.9e-29 102.9 0.0 2.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX90218.1 - 5.8e-08 32.9 0.7 1.9e-05 24.6 0.8 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX90218.1 - 9.6e-07 28.5 0.4 2e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EAX90218.1 - 2e-06 27.2 36.6 2.7e-06 26.8 36.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 EAX90218.1 - 5.1e-06 27.1 0.0 8.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAX90218.1 - 7.2e-06 25.9 0.2 1.3e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EAX90218.1 - 0.00015 21.3 0.3 0.001 18.5 0.2 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAX90218.1 - 0.00017 21.5 0.1 0.00035 20.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EAX90218.1 - 0.0058 16.2 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EAX90218.1 - 0.0064 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_27 PF13514.6 EAX90218.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAX90218.1 - 0.0091 16.1 0.2 0.019 15.1 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX90218.1 - 0.019 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EAX90218.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX90218.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EAX90218.1 - 0.044 13.4 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EAX90218.1 - 0.051 13.8 0.1 0.097 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EAX90218.1 - 0.059 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) IstB_IS21 PF01695.17 EAX90218.1 - 0.13 12.0 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EAX90218.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EAX90218.1 - 0.23 11.6 0.2 0.4 10.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX90218.1 - 0.26 11.5 0.2 0.69 10.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L18A PF01775.17 EAX90221.1 - 8.2e-44 148.6 0.1 1.1e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Bse634I PF07832.11 EAX90221.1 - 0.074 12.4 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease ArfGap PF01412.18 EAX90222.1 - 6.7e-37 126.1 0.1 1.2e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PSP PF04046.16 EAX90223.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3839 PF12943.7 EAX90224.1 - 4.8e-27 95.0 0.3 5.1e-27 94.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX90225.1 - 1.3e-120 401.3 10.6 1.6e-120 401.0 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX90225.1 - 0.01 16.3 2.1 1.8 9.0 0.0 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FYRC PF05965.14 EAX90228.1 - 2.1e-11 43.8 0.0 4.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus SNF2_N PF00176.23 EAX90228.1 - 0.00036 19.4 0.1 0.001 17.9 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain FYRN PF05964.14 EAX90228.1 - 0.0037 17.1 2.6 0.0041 16.9 0.5 2.2 2 0 0 2 2 2 1 F/Y-rich N-terminus DUF1086 PF06461.11 EAX90228.1 - 0.011 15.6 0.2 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) PolyA_pol PF01743.20 EAX90229.1 - 1e-24 87.3 0.1 2.5e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAX90229.1 - 0.0007 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A YabA PF06156.13 EAX90230.1 - 0.045 14.4 4.6 0.06 14.0 3.1 2.0 2 0 0 2 2 2 0 Initiation control protein YabA SelB-wing_3 PF09107.11 EAX90230.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF1640 PF07798.11 EAX90230.1 - 0.12 12.4 2.2 0.19 11.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GvpK PF05121.12 EAX90232.1 - 0.38 10.8 4.6 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K DUF3839 PF12943.7 EAX90233.1 - 2e-156 518.6 16.1 2.5e-156 518.3 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX90233.1 - 0.088 13.1 0.4 1.5 9.1 0.1 2.9 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX90233.1 - 0.17 11.7 1.4 0.37 10.6 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX90233.1 - 0.25 11.9 5.2 0.23 12.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX90233.1 - 9.1 6.8 8.3 2.5 8.6 0.8 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Methyltransf_12 PF08242.12 EAX90234.1 - 0.023 15.5 1.1 8.1 7.3 0.0 4.6 3 0 0 3 3 3 0 Methyltransferase domain CENP-T_C PF15511.6 EAX90234.1 - 0.028 14.5 0.4 13 6.0 0.0 3.1 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T histone fold RNase_PH PF01138.21 EAX90234.1 - 0.05 14.1 3.7 2.4 8.7 0.0 5.0 4 1 1 5 5 5 0 3' exoribonuclease family, domain 1 Methyltransf_31 PF13847.6 EAX90234.1 - 0.62 9.8 9.0 3.5 7.4 0.0 5.6 5 0 0 5 5 5 0 Methyltransferase domain Dynein_AAA_lid PF17852.1 EAX90234.1 - 3.6 7.7 7.5 6.4 6.9 0.2 5.1 4 1 0 4 4 4 0 Dynein heavy chain AAA lid domain CSN8_PSD8_EIF3K PF10075.9 EAX90236.1 - 9.5e-31 106.7 1.0 1.3e-30 106.3 1.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EAX90236.1 - 5.5e-07 29.2 0.2 6.9e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family ETC_C1_NDUFA4 PF04800.12 EAX90236.1 - 0.0096 16.2 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF4358 PF14270.6 EAX90236.1 - 0.021 15.1 0.1 0.051 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Toprim_Crpt PF13342.6 EAX90236.1 - 0.024 14.6 0.1 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase PCI PF01399.27 EAX90236.1 - 0.029 14.9 1.4 0.66 10.5 0.9 3.1 1 1 1 2 2 2 0 PCI domain NOP5NT PF08156.13 EAX90236.1 - 0.08 13.3 0.4 0.28 11.6 0.2 2.0 1 1 0 1 1 1 0 NOP5NT (NUC127) domain DUF4430 PF14478.6 EAX90236.1 - 0.16 12.6 0.2 0.47 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) Katanin_con80 PF13925.6 EAX90237.1 - 0.08 13.0 0.3 15 5.6 0.0 2.8 3 0 0 3 3 3 0 con80 domain of Katanin Gly_rich PF12810.7 EAX90238.1 - 9.4e-36 123.9 76.2 1.2e-35 123.6 76.2 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3839 PF12943.7 EAX90239.1 - 2.4e-149 495.4 12.9 3e-149 495.1 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX90239.1 - 0.09 13.2 0.5 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX90239.1 - 0.12 12.9 8.1 2.1 8.8 0.4 3.5 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2960 PF11173.8 EAX90240.1 - 0.04 14.4 0.3 0.11 12.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) DUF1146 PF06612.11 EAX90241.1 - 0.045 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX90241.1 - 0.074 13.2 0.9 0.3 11.2 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Pkinase PF00069.25 EAX90242.1 - 9.6e-56 189.1 0.0 1.3e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90242.1 - 8.4e-38 130.1 0.0 1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX90242.1 - 0.0011 19.0 0.2 0.0031 17.4 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX90242.1 - 0.0017 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX90242.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX90242.1 - 0.0026 17.2 0.1 0.0046 16.3 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EAX90242.1 - 0.083 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 EAX90242.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Guanylate_cyc PF00211.20 EAX90243.1 - 2.9e-42 144.4 0.0 1.4e-41 142.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX90243.1 - 6e-12 45.7 0.6 1.6e-11 44.3 0.6 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX90243.1 - 0.011 15.8 0.2 0.025 14.6 0.2 1.6 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 EAX90243.1 - 0.014 14.8 0.3 0.026 13.9 0.3 1.5 1 0 0 1 1 1 0 Heme NO binding associated PAS_4 PF08448.10 EAX90243.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold Sigma_reg_N PF13800.6 EAX90244.1 - 0.042 14.1 0.8 0.042 14.1 0.8 3.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal PSP PF04046.16 EAX90245.1 - 0.086 12.7 1.3 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90246.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90247.1 - 0.018 15.5 0.5 0.037 14.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX90248.1 - 2.8e-05 24.1 3.0 2.8e-05 24.1 3.0 4.3 4 2 1 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX90248.1 - 0.026 14.1 18.2 0.051 13.2 5.8 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX90248.1 - 0.21 11.7 6.2 10 6.2 0.5 3.5 2 1 2 4 4 4 0 Plant transposase (Ptta/En/Spm family) DUF2120 PF09893.9 EAX90248.1 - 0.35 11.0 4.0 1.5 8.9 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) YmaF PF12788.7 EAX90248.1 - 0.69 10.5 3.1 7.1 7.2 1.2 3.1 3 1 0 3 3 3 0 YmaF family T5orf172 PF10544.9 EAX90250.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX90250.1 - 0.0061 16.4 1.0 0.043 13.7 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX90250.1 - 0.1 12.1 0.5 0.29 10.6 0.2 1.7 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX90251.1 - 1.2e-34 118.5 0.0 2.3e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX90252.1 - 5.8e-05 22.7 1.7 5.8e-05 22.7 1.7 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX90252.1 - 0.0046 17.0 0.6 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1722 PF08349.11 EAX90252.1 - 0.081 13.2 1.7 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) ARA70 PF12489.8 EAX90253.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Ank_2 PF12796.7 EAX90254.1 - 1.4e-20 73.7 1.4 2.3e-11 44.1 0.5 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90254.1 - 3.1e-17 62.7 0.4 8.6e-09 35.8 0.0 2.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90254.1 - 1.7e-15 56.9 0.9 4.8e-06 26.7 0.0 4.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX90254.1 - 9.1e-14 51.2 3.4 4.4e-05 23.7 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EAX90254.1 - 3.5e-13 48.4 0.1 0.0026 18.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat SnAPC_2_like PF11035.8 EAX90254.1 - 0.053 13.7 0.6 0.075 13.2 0.6 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF3677 PF12432.8 EAX90254.1 - 0.063 13.6 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Abi_C PF14355.6 EAX90254.1 - 0.14 12.3 0.2 0.41 10.8 0.2 1.8 1 0 0 1 1 1 0 Abortive infection C-terminus Kelch_4 PF13418.6 EAX90255.1 - 8.4e-27 92.9 0.5 2e-07 30.9 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX90255.1 - 3.4e-21 74.7 8.9 0.00014 22.0 0.5 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EAX90255.1 - 1.5e-19 69.8 3.3 3e-05 24.2 0.0 5.9 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAX90255.1 - 2.9e-14 52.7 7.8 5.3e-06 26.3 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EAX90255.1 - 3.8e-14 52.0 10.2 9.1e-06 25.2 0.3 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EAX90255.1 - 3.8e-13 48.8 4.8 1.1e-05 25.2 0.4 4.7 5 0 0 5 5 5 3 Kelch motif Metallophos PF00149.28 EAX90256.1 - 1.7e-27 97.2 0.4 2.3e-27 96.8 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fels1 PF05666.11 EAX90256.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like TSC22 PF01166.18 EAX90258.1 - 2.2e-13 50.3 40.4 0.00012 22.3 3.9 6.2 1 1 6 7 7 6 6 TSC-22/dip/bun family ZapB PF06005.12 EAX90258.1 - 2.8e-11 43.7 42.0 0.0011 19.3 7.6 4.3 1 1 2 4 4 4 4 Cell division protein ZapB APG6_N PF17675.1 EAX90258.1 - 8.8e-11 42.5 26.3 3e-05 24.6 4.7 3.2 1 1 2 3 3 3 3 Apg6 coiled-coil region DivIC PF04977.15 EAX90258.1 - 4.8e-09 35.9 36.7 0.01 15.6 5.1 5.0 1 1 6 7 7 7 6 Septum formation initiator bZIP_1 PF00170.21 EAX90258.1 - 4.9e-09 36.1 41.4 0.0049 16.9 5.2 5.7 2 2 3 6 6 6 4 bZIP transcription factor CENP-F_leu_zip PF10473.9 EAX90258.1 - 2.9e-08 33.9 27.2 5.5e-05 23.2 12.6 2.4 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 EAX90258.1 - 2.7e-07 30.8 24.3 0.032 14.4 1.2 4.0 1 1 3 4 4 4 3 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 EAX90258.1 - 4.5e-07 29.9 24.8 0.0018 18.1 5.2 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF724) ADIP PF11559.8 EAX90258.1 - 1.3e-06 28.6 39.1 0.021 14.9 9.7 3.2 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 EAX90258.1 - 1.4e-06 28.9 23.8 0.00072 20.1 8.8 2.1 1 1 1 2 2 2 2 Fez1 ATG16 PF08614.11 EAX90258.1 - 8.4e-06 26.2 23.8 0.0024 18.1 12.4 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HALZ PF02183.18 EAX90258.1 - 1e-05 25.7 29.0 0.2 11.9 1.3 5.8 2 2 4 7 7 7 5 Homeobox associated leucine zipper KASH_CCD PF14662.6 EAX90258.1 - 1.2e-05 25.3 36.8 0.00027 20.8 22.2 2.8 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 EAX90258.1 - 1.4e-05 24.5 25.5 0.0006 19.1 7.0 2.7 1 1 1 2 2 2 2 HAP1 N-terminal conserved region ERM PF00769.19 EAX90258.1 - 3.6e-05 23.7 17.2 0.0026 17.6 16.9 2.1 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF4472 PF14739.6 EAX90258.1 - 8.5e-05 23.3 26.7 0.0041 17.8 4.3 3.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4472) CALCOCO1 PF07888.11 EAX90258.1 - 9.8e-05 21.4 18.1 0.00014 20.9 18.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 EAX90258.1 - 0.00039 19.6 27.2 0.021 13.9 8.9 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 BicD PF09730.9 EAX90258.1 - 0.0004 19.0 8.9 0.0004 19.0 8.9 2.1 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D Spc7 PF08317.11 EAX90258.1 - 0.00087 18.3 29.4 0.03 13.2 14.3 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein YabA PF06156.13 EAX90258.1 - 0.00087 19.9 34.3 0.8 10.4 6.5 4.0 1 1 2 3 3 3 1 Initiation control protein YabA Ax_dynein_light PF10211.9 EAX90258.1 - 0.0012 18.9 33.3 0.056 13.4 6.5 3.2 1 1 3 4 4 4 3 Axonemal dynein light chain GAS PF13851.6 EAX90258.1 - 0.0013 18.1 33.9 0.069 12.5 15.0 3.0 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding LPP PF04728.13 EAX90258.1 - 0.0014 19.0 18.9 0.0042 17.4 2.4 4.5 2 1 1 3 3 3 1 Lipoprotein leucine-zipper PspA_IM30 PF04012.12 EAX90258.1 - 0.0015 18.1 13.3 0.29 10.7 3.5 3.1 1 1 0 3 3 3 1 PspA/IM30 family DUF1664 PF07889.12 EAX90258.1 - 0.0019 18.2 17.3 0.15 12.1 1.8 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EAX90258.1 - 0.002 18.2 35.6 0.14 12.3 11.4 3.2 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 EAX90258.1 - 0.0025 17.5 27.2 0.04 13.5 10.2 2.8 1 1 2 3 3 3 3 Intermediate filament protein LRRFIP PF09738.9 EAX90258.1 - 0.0042 16.6 28.2 0.026 14.0 4.5 3.0 1 1 1 3 3 3 2 LRRFIP family DUF5082 PF16888.5 EAX90258.1 - 0.0046 17.2 32.8 0.16 12.3 5.1 3.7 1 1 0 2 2 2 1 Domain of unknown function (DUF5082) Swi5 PF07061.11 EAX90258.1 - 0.0053 16.8 32.9 0.12 12.5 5.2 4.4 1 1 3 4 4 4 1 Swi5 DUF812 PF05667.11 EAX90258.1 - 0.007 15.3 23.1 0.026 13.4 23.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF812) JIP_LZII PF16471.5 EAX90258.1 - 0.0089 16.2 24.7 1.3 9.3 1.4 5.9 1 1 3 4 4 4 1 JNK-interacting protein leucine zipper II MAD PF05557.13 EAX90258.1 - 0.0094 14.4 27.7 0.051 11.9 11.3 2.4 1 1 1 2 2 2 2 Mitotic checkpoint protein Leu_zip PF15294.6 EAX90258.1 - 0.012 15.1 13.4 0.012 15.1 13.4 2.7 1 1 1 2 2 2 0 Leucine zipper PRKG1_interact PF15898.5 EAX90258.1 - 0.018 15.9 31.9 2.7 8.9 3.1 3.9 1 1 2 3 3 2 0 cGMP-dependent protein kinase interacting domain BRE1 PF08647.11 EAX90258.1 - 0.019 15.1 10.1 0.019 15.1 10.1 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 EAX90258.1 - 0.019 15.2 27.2 0.86 9.8 13.8 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 K-box PF01486.17 EAX90258.1 - 0.02 15.1 33.6 3.2 8.0 1.3 6.0 1 1 4 5 5 5 0 K-box region Occludin_ELL PF07303.13 EAX90258.1 - 0.021 15.5 20.6 0.15 12.8 3.0 3.4 1 1 2 3 3 3 0 Occludin homology domain DUF4201 PF13870.6 EAX90258.1 - 0.021 14.6 30.8 0.16 11.7 15.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 EAX90258.1 - 0.024 14.0 26.6 0.16 11.3 7.3 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 EAX90258.1 - 0.026 14.9 25.7 0.72 10.3 7.3 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Tropomyosin PF00261.20 EAX90258.1 - 0.026 13.9 17.0 0.48 9.7 6.9 2.3 2 0 0 2 2 2 0 Tropomyosin DUF641 PF04859.12 EAX90258.1 - 0.027 14.8 5.2 0.027 14.8 5.2 2.8 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SOGA PF11365.8 EAX90258.1 - 0.03 15.4 24.9 1.5 10.0 7.1 3.8 1 1 2 3 3 3 0 Protein SOGA PI3K_P85_iSH2 PF16454.5 EAX90258.1 - 0.053 13.1 31.2 0.11 12.1 5.3 3.3 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4618 PF15397.6 EAX90258.1 - 0.054 12.9 29.3 2.6 7.4 14.8 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) UPF0242 PF06785.11 EAX90258.1 - 0.075 13.1 34.9 25 4.9 9.4 3.2 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus GP57 PF17594.2 EAX90258.1 - 0.086 12.6 0.5 4.6 7.0 0.0 3.3 3 1 0 4 4 3 0 Phage Tail fiber assembly helper gene product 57 DUF2205 PF10224.9 EAX90258.1 - 0.12 12.4 33.8 0.94 9.5 6.1 4.8 1 1 5 6 6 6 0 Short coiled-coil protein GIT_CC PF16559.5 EAX90258.1 - 0.15 12.0 43.6 0.16 11.8 5.6 5.3 1 1 4 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor End3 PF12761.7 EAX90258.1 - 0.17 12.1 25.8 3.4 7.8 7.2 2.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pox_A_type_inc PF04508.12 EAX90258.1 - 0.18 11.7 18.6 0.71 9.8 0.0 6.6 7 0 0 7 7 6 0 Viral A-type inclusion protein repeat TolA_bind_tri PF16331.5 EAX90258.1 - 0.2 11.8 23.4 2 8.6 1.7 4.2 2 1 1 4 4 4 0 TolA binding protein trimerisation DUF4094 PF13334.6 EAX90258.1 - 0.22 12.0 14.2 0.27 11.7 2.2 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF2968 PF11180.8 EAX90258.1 - 0.22 11.1 13.6 0.58 9.8 2.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) TMPIT PF07851.13 EAX90258.1 - 0.28 10.4 23.3 1.3 8.2 9.9 2.4 1 1 1 2 2 2 0 TMPIT-like protein TACC_C PF05010.14 EAX90258.1 - 0.33 10.7 25.7 0.067 13.0 10.2 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HMMR_C PF15908.5 EAX90258.1 - 0.36 11.1 29.3 9.2 6.5 0.5 4.6 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor C-terminal Synaptobrevin PF00957.21 EAX90258.1 - 0.39 10.5 23.6 0.79 9.6 0.8 4.9 1 1 5 6 6 5 0 Synaptobrevin HAUS-augmin3 PF14932.6 EAX90258.1 - 0.43 10.1 25.4 0.29 10.7 6.5 3.3 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Rab5-bind PF09311.11 EAX90258.1 - 0.45 9.9 24.0 0.13 11.6 3.8 3.0 1 1 1 3 3 3 0 Rabaptin-like protein Lzipper-MIP1 PF14389.6 EAX90258.1 - 0.45 10.8 13.6 0.26 11.6 0.5 4.0 5 1 0 5 5 3 0 Leucine-zipper of ternary complex factor MIP1 FAM76 PF16046.5 EAX90258.1 - 0.51 9.7 22.9 1 8.6 9.0 2.2 1 1 1 2 2 2 0 FAM76 protein Rootletin PF15035.6 EAX90258.1 - 0.72 9.8 31.5 1.3 9.0 19.6 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GPS2_interact PF15784.5 EAX90258.1 - 0.77 10.2 11.8 0.24 11.9 1.4 3.4 3 1 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF4140 PF13600.6 EAX90258.1 - 0.91 10.0 12.6 2.4 8.7 1.4 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CtIP_N PF10482.9 EAX90258.1 - 0.95 9.5 39.3 4.2 7.4 5.7 4.8 2 2 2 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain HemX PF04375.14 EAX90258.1 - 1.1 8.5 22.9 0.24 10.7 8.7 2.2 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Phlebovirus_NSM PF07246.11 EAX90258.1 - 1.2 8.5 24.2 1.3 8.3 9.6 2.7 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Lectin_N PF03954.14 EAX90258.1 - 1.2 8.9 20.3 1 9.1 3.4 3.8 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain NRBF2 PF08961.10 EAX90258.1 - 1.3 8.5 33.0 0.89 9.1 2.8 4.2 1 1 4 5 5 5 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 EAX90258.1 - 1.6 8.9 39.8 1.6 8.9 1.1 6.1 2 2 3 6 6 6 0 Basic region leucine zipper CLZ PF16526.5 EAX90258.1 - 2 8.9 13.3 0.91 9.9 1.4 3.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 EAX90258.1 - 2.4 8.5 25.7 0.45 10.9 5.7 4.2 1 1 3 4 4 4 0 Tup N-terminal WEMBL PF05701.11 EAX90258.1 - 3.3 6.3 18.7 1.1 7.9 8.6 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DHR10 PF18595.1 EAX90258.1 - 3.9 7.6 20.4 12 6.0 3.7 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Lebercilin PF15619.6 EAX90258.1 - 4.2 7.0 36.5 5.9 6.5 4.6 4.4 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FOXP-CC PF16159.5 EAX90258.1 - 4.9 7.9 4.9 4.9 7.9 1.1 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Seryl_tRNA_N PF02403.22 EAX90258.1 - 5 7.4 37.3 0.52 10.6 9.1 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.19 EAX90258.1 - 5.1 6.7 32.1 0.82 9.3 7.7 3.7 1 1 1 2 2 1 0 GrpE Tropomyosin_1 PF12718.7 EAX90258.1 - 5.3 7.2 31.9 2.2 8.4 8.6 3.2 1 1 2 3 3 3 0 Tropomyosin like DUF4407 PF14362.6 EAX90258.1 - 5.5 6.3 18.9 56 2.9 18.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 EAX90258.1 - 5.9 7.3 27.4 1.8e+04 -8.9 27.4 3.2 1 1 0 1 1 0 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 PF14197.6 EAX90258.1 - 6.3 7.0 31.6 40 4.4 13.8 4.6 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 DUF2730 PF10805.8 EAX90258.1 - 7.5 6.7 8.3 22 5.2 1.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) HMMR_N PF15905.5 EAX90258.1 - 8.5 5.8 29.4 15 5.0 10.1 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4200 PF13863.6 EAX90258.1 - 9 6.7 28.6 1.1 9.6 4.0 3.8 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 EAX90258.1 - 9 6.9 23.5 22 5.7 6.8 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2203 PF09969.9 EAX90258.1 - 9.5 7.0 11.8 1.2 9.8 2.9 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tho2 PF11262.8 EAX90258.1 - 9.8 5.3 27.4 3.6 6.7 5.6 3.1 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Ank_2 PF12796.7 EAX90259.1 - 1.1e-44 150.9 6.9 1.5e-17 63.9 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90259.1 - 1.3e-29 102.1 0.5 1.7e-08 34.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90259.1 - 2.6e-24 84.9 1.3 1.1e-09 38.4 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90259.1 - 2.4e-23 79.7 2.3 0.00014 22.0 0.0 7.0 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAX90259.1 - 7e-23 80.0 0.3 7.3e-06 26.2 0.0 6.5 5 1 1 6 6 6 3 Ankyrin repeat baeRF_family7 PF18849.1 EAX90259.1 - 0.057 13.6 0.1 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 DivIC PF04977.15 EAX90259.1 - 0.069 12.9 0.8 0.15 11.8 0.8 1.6 1 0 0 1 1 1 0 Septum formation initiator MA3 PF02847.17 EAX90259.1 - 0.11 12.5 0.4 58 3.7 0.1 3.8 3 1 2 5 5 5 0 MA3 domain FmdA_AmdA PF03069.15 EAX90259.1 - 0.14 10.9 0.0 2.2 7.1 0.0 2.4 2 1 1 3 3 3 0 Acetamidase/Formamidase family TSC22 PF01166.18 EAX90259.1 - 0.42 11.0 2.9 12 6.3 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Lectin_leg-like PF03388.13 EAX90260.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family Sen15 PF09631.10 EAX90260.1 - 0.081 13.2 0.7 4.5 7.6 0.0 3.0 2 2 1 3 3 3 0 Sen15 protein FapA PF03961.13 EAX90260.1 - 0.17 10.4 4.7 0.28 9.7 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med9 PF07544.13 EAX90260.1 - 0.82 9.8 5.1 0.56 10.3 2.3 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 EAX90261.1 - 0.049 13.8 1.5 4.3 7.5 0.1 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Glu-tRNAGln PF02686.15 EAX90261.1 - 0.082 13.2 0.0 2.6 8.4 0.1 3.1 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF16 PF01519.16 EAX90261.1 - 0.56 10.7 4.1 0.71 10.4 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF604 PF04646.12 EAX90262.1 - 0.46 9.8 4.8 0.41 10.0 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF604 ROK PF00480.20 EAX90263.1 - 4.6e-52 177.3 0.0 5.9e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 EAX90263.1 - 0.0061 15.6 0.0 0.14 11.1 0.0 2.5 2 1 0 2 2 2 1 Glucokinase HNH_repeat PF18780.1 EAX90263.1 - 0.042 13.6 0.3 0.081 12.7 0.3 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat RNA_pol_Rpb5_C PF01191.19 EAX90263.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF1450 PF07293.11 EAX90263.1 - 0.1 12.4 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) DUF713 PF05218.14 EAX90264.1 - 0.0014 18.4 2.4 0.0014 18.4 2.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF713) Baculo_PEP_C PF04513.12 EAX90264.1 - 0.0025 17.9 5.3 0.18 11.8 0.0 2.7 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EAX90264.1 - 0.006 16.1 9.7 0.022 14.3 3.1 2.6 1 1 2 3 3 3 1 fzo-like conserved region CdvA PF18822.1 EAX90264.1 - 0.042 13.7 16.9 0.061 13.2 3.4 3.5 2 1 0 3 3 3 0 CdvA-like coiled-coil domain Helo_like_N PF17111.5 EAX90264.1 - 0.045 13.1 8.0 1 8.7 1.4 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Fe-S_assembly PF04384.13 EAX90264.1 - 0.28 11.8 3.0 0.63 10.7 0.1 2.8 3 0 0 3 3 3 0 Iron-sulphur cluster assembly Apolipoprotein PF01442.18 EAX90264.1 - 0.57 10.0 9.3 0.29 11.0 5.3 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EAX90264.1 - 0.72 10.1 2.7 8.3 6.7 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SBDS_C PF09377.10 EAX90264.1 - 0.79 9.8 4.7 1.1 9.4 4.7 1.4 1 1 0 1 1 1 0 SBDS protein C-terminal domain FlaC_arch PF05377.11 EAX90264.1 - 1.5 9.3 7.4 5.1 7.6 1.2 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CorA PF01544.18 EAX90264.1 - 1.9 7.7 8.6 0.2 10.9 1.6 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EAX90264.1 - 2.1 8.4 8.6 1.5 8.9 0.6 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EAX90264.1 - 2.6 8.4 9.8 1.3 9.3 3.4 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Cob_adeno_trans PF01923.18 EAX90264.1 - 2.8 8.0 6.4 0.26 11.4 0.8 2.1 3 0 0 3 3 3 0 Cobalamin adenosyltransferase Phage_GPO PF05929.11 EAX90264.1 - 3.1 7.4 10.9 1.9 8.1 5.0 2.3 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 EAX90264.1 - 4.5 7.4 16.2 7.9 6.7 4.3 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family STAT_alpha PF01017.20 EAX90264.1 - 5 7.0 14.9 0.76 9.6 7.1 2.6 2 1 0 2 2 2 0 STAT protein, all-alpha domain YabA PF06156.13 EAX90264.1 - 5.3 7.7 13.5 7.3 7.3 7.9 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Folliculin PF11704.8 EAX90264.1 - 5.8 6.7 7.3 1.4e+02 2.3 7.3 2.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Allexi_40kDa PF05549.11 EAX90264.1 - 6 6.3 7.4 3.3 7.1 3.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Exonuc_VII_L PF02601.15 EAX90264.1 - 6.1 6.3 10.6 18 4.7 10.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 EAX90264.1 - 6.8 7.1 10.6 0.73 10.2 0.8 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_L6e PF01159.19 EAX90265.1 - 2.2e-09 37.9 0.2 0.00046 20.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e KOW PF00467.29 EAX90265.1 - 0.29 11.1 5.0 0.62 10.1 5.0 1.6 1 0 0 1 1 1 0 KOW motif DUF5497 PF17601.2 EAX90266.1 - 0.0053 17.0 0.5 0.094 13.0 0.0 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF5497) DUF2482 PF10655.9 EAX90266.1 - 4.4 7.9 8.8 5.5 7.6 1.7 2.5 1 1 1 2 2 2 0 Hypothetical protein of unknown function (DUF2482) EF-hand_7 PF13499.6 EAX90267.1 - 0.016 15.7 0.3 0.46 11.0 0.2 2.3 1 1 1 2 2 2 0 EF-hand domain pair LTXXQ PF07813.12 EAX90267.1 - 0.059 14.1 0.9 1.3 9.8 0.2 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein Ribosomal_S17_N PF16205.5 EAX90268.1 - 1.7e-27 95.6 0.5 2.9e-27 94.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAX90268.1 - 1.7e-26 92.1 0.8 1.7e-26 92.1 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 PCB_OB PF17092.5 EAX90268.1 - 0.017 15.8 0.0 0.031 15.0 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF5487 PF17589.2 EAX90268.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5487) Aminotran_5 PF00266.19 EAX90269.1 - 4.2e-36 124.7 0.0 4.8e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Meiosis_expr PF15163.6 EAX90270.1 - 0.058 14.1 0.5 0.1 13.3 0.2 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX90270.1 - 0.19 11.5 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Ank_2 PF12796.7 EAX90271.1 - 0.0018 18.8 0.1 0.0053 17.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90271.1 - 0.0052 17.3 0.1 0.013 16.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zinc-ribbons_6 PF07191.12 EAX90271.1 - 0.023 14.7 4.9 0.92 9.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.6 EAX90271.1 - 0.61 10.5 8.0 8.1 6.9 0.2 3.3 2 1 1 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.19 EAX90271.1 - 1.3 9.1 4.7 0.65 10.0 0.7 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA O-antigen_lig PF13425.6 EAX90271.1 - 2.8 6.6 4.8 3.9 6.2 4.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein C1_2 PF03107.16 EAX90271.1 - 5.9 7.3 9.8 0.65 10.4 3.0 2.6 3 0 0 3 3 3 0 C1 domain Rad51 PF08423.11 EAX90272.1 - 1.7e-125 417.5 0.0 2e-125 417.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EAX90272.1 - 1.2e-11 44.6 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EAX90272.1 - 6.8e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAX90272.1 - 1.5e-07 31.0 0.0 3.3e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 EAX90272.1 - 5.1e-05 23.8 1.1 0.00014 22.4 1.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EAX90272.1 - 0.0026 17.5 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_24 PF13479.6 EAX90272.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3215 PF11503.8 EAX90272.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) PAXNEB PF05625.11 EAX90272.1 - 0.13 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein Ank_4 PF13637.6 EAX90273.1 - 1.4e-06 28.7 0.0 1.8e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX90273.1 - 6.9e-05 23.1 0.0 0.2 12.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX90273.1 - 7.4e-05 23.3 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90273.1 - 0.00035 20.8 0.0 0.094 13.1 0.0 1.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90274.1 - 3.4e-34 116.6 8.9 3.4e-34 116.6 8.9 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90274.1 - 0.00014 22.4 0.1 0.00044 20.8 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90274.1 - 0.13 12.8 0.9 20 5.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90275.1 - 4.7e-45 152.1 28.9 2e-15 57.2 3.8 5.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX90275.1 - 1.2e-39 134.1 5.4 1.2e-39 134.1 5.4 4.3 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX90275.1 - 2.1e-39 132.3 7.3 1.4e-08 34.8 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 EAX90275.1 - 4.1e-39 132.5 9.4 7.6e-11 42.3 0.1 7.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90275.1 - 5e-33 112.7 11.7 5e-11 42.6 0.5 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90275.1 - 6.1e-28 93.8 13.9 2.6e-05 24.3 0.1 7.9 8 1 0 8 8 8 4 Ankyrin repeat Peptidase_M16 PF00675.20 EAX90275.1 - 0.013 15.5 2.0 0.78 9.7 0.1 3.4 1 1 3 4 4 4 0 Insulinase (Peptidase family M16) DUF1883 PF08980.10 EAX90275.1 - 0.14 12.1 0.4 15 5.6 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1883) Mic1 PF07035.12 EAX90275.1 - 0.25 11.1 2.7 64 3.2 0.0 3.9 2 1 0 4 4 4 0 Colon cancer-associated protein Mic1-like Gly_rich PF12810.7 EAX90277.1 - 2.4e-51 175.0 33.9 2.9e-51 174.8 33.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Pkinase PF00069.25 EAX90279.1 - 1.9e-69 234.0 0.1 2.3e-69 233.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90279.1 - 9.5e-41 139.8 0.0 1.2e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX90279.1 - 3e-09 36.3 0.4 4.5e-09 35.7 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX90279.1 - 7.2e-08 31.6 0.1 1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX90279.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX90279.1 - 0.00076 19.1 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAX90279.1 - 0.0017 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX90279.1 - 0.0045 16.6 0.4 0.0078 15.8 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 EAX90279.1 - 0.16 11.9 2.3 0.32 11.0 2.3 1.6 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins LRR_6 PF13516.6 EAX90280.1 - 1.7e-25 86.9 42.3 0.00013 21.7 0.3 12.0 12 0 0 12 12 12 8 Leucine Rich repeat LRR_8 PF13855.6 EAX90280.1 - 0.00011 21.8 18.3 0.0017 18.1 0.2 6.3 5 2 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EAX90280.1 - 0.00092 19.6 28.5 0.072 13.5 0.2 6.9 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX90280.1 - 0.0027 18.0 20.5 32 5.6 0.4 9.6 12 0 0 12 12 12 1 Leucine Rich Repeat TPR_10 PF13374.6 EAX90280.1 - 0.05 13.5 0.4 0.17 11.8 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Bromodomain PF00439.25 EAX90281.1 - 3.9e-23 81.3 0.0 5.4e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain Viral_DNA_bi PF02236.17 EAX90281.1 - 0.00055 20.1 0.0 0.00091 19.4 0.0 1.3 1 0 0 1 1 1 1 Viral DNA-binding protein, all alpha domain PLD_C PF12357.8 EAX90281.1 - 0.085 12.8 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase D C terminal DUF563 PF04577.14 EAX90282.1 - 4.8e-22 79.1 0.0 8.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Exonuc_VII_L PF02601.15 EAX90282.1 - 0.62 9.6 2.5 20 4.6 0.1 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Antimicrobial_7 PF08102.11 EAX90284.1 - 0.058 13.6 1.4 0.14 12.4 1.4 1.9 1 1 0 1 1 1 0 Scorpion antimicrobial peptide Gly-zipper_Omp PF13488.6 EAX90285.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX90285.1 - 0.24 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX90285.1 - 0.85 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Ank_2 PF12796.7 EAX90286.1 - 6.6e-71 234.9 46.2 3.8e-18 65.8 4.6 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90286.1 - 8.1e-57 187.3 19.7 6.9e-08 32.6 0.6 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAX90286.1 - 9e-53 176.0 18.9 3.8e-12 46.5 0.3 9.5 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90286.1 - 8.7e-45 145.5 13.9 3.2e-06 27.0 0.3 10.2 9 0 0 9 9 9 7 Ankyrin repeat DUF3447 PF11929.8 EAX90286.1 - 2e-34 117.4 6.6 2e-34 117.4 6.6 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX90286.1 - 5.3e-31 106.3 19.3 2.3e-10 40.5 0.4 7.5 4 1 4 8 8 8 5 Ankyrin repeats (many copies) HECT PF00632.25 EAX90287.1 - 7.9e-87 291.6 0.6 1.8e-86 290.4 0.6 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EAX90287.1 - 3e-09 37.0 1.7 3e-09 37.0 1.7 1.8 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A CBS PF00571.28 EAX90288.1 - 0.01 16.3 0.0 6.6 7.3 0.0 2.6 2 0 0 2 2 2 0 CBS domain Ank_4 PF13637.6 EAX90290.1 - 1.1e-61 204.4 0.6 1.3e-12 48.0 0.0 9.0 3 1 7 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX90290.1 - 1.4e-50 167.6 0.0 2e-07 31.1 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.7 EAX90290.1 - 1.1e-49 167.0 10.1 1.9e-16 60.4 0.1 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90290.1 - 6.9e-47 152.0 0.1 6.8e-05 23.0 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX90290.1 - 2.6e-40 135.9 3.6 5.9e-09 36.0 0.0 6.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90290.1 - 3e-36 123.2 2.7 3e-36 123.2 2.7 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) 3Beta_HSD PF01073.19 EAX90290.1 - 3.6e-05 22.9 13.0 1.3 7.9 0.3 5.8 2 1 5 7 7 7 4 3-beta hydroxysteroid dehydrogenase/isomerase family PH_8 PF15409.6 EAX90290.1 - 4.5e-05 23.7 0.8 60 4.0 0.0 6.2 2 1 5 7 7 7 0 Pleckstrin homology domain Apc13p PF05839.11 EAX90290.1 - 0.047 13.9 7.3 18 5.6 0.8 4.9 1 1 3 4 4 4 0 Apc13p protein NOA36 PF06524.12 EAX90290.1 - 2.7 7.2 9.7 5 6.3 9.7 1.5 1 0 0 1 1 1 0 NOA36 protein DUF960 PF06124.11 EAX90291.1 - 0.016 15.8 0.2 0.083 13.5 0.1 2.2 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) DUF4840 PF16128.5 EAX90291.1 - 0.02 15.0 0.6 0.32 11.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4840) ASH PF15780.5 EAX90291.1 - 0.043 14.0 1.5 4 7.7 0.0 3.8 4 1 1 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ank_2 PF12796.7 EAX90292.1 - 2.3e-25 89.0 0.0 7.3e-08 32.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90292.1 - 1.2e-21 76.1 0.0 1.1e-05 25.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX90292.1 - 7.9e-19 67.5 0.0 2e-08 34.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90292.1 - 9e-17 59.5 0.0 0.00039 20.6 0.0 4.2 5 0 0 5 5 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX90292.1 - 1.3e-16 60.7 0.0 8.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Allexi_40kDa PF05549.11 EAX90292.1 - 0.0022 17.5 1.3 0.0029 17.2 1.3 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein Swi5 PF07061.11 EAX90292.1 - 0.08 13.0 2.2 0.16 12.0 2.2 1.5 1 0 0 1 1 1 0 Swi5 BST2 PF16716.5 EAX90292.1 - 0.081 13.5 5.9 0.39 11.3 4.2 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Csm2_III-A PF03750.13 EAX90292.1 - 0.083 13.7 2.3 0.18 12.6 2.3 1.5 1 0 0 1 1 1 0 Csm2 Type III-A FlxA PF14282.6 EAX90292.1 - 0.084 12.9 6.0 0.15 12.0 6.0 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF3375 PF11855.8 EAX90292.1 - 0.11 11.4 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF4407 PF14362.6 EAX90292.1 - 0.12 11.7 0.5 0.17 11.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 EAX90292.1 - 0.13 12.5 6.1 0.31 11.3 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 EAX90292.1 - 0.17 11.7 1.7 0.35 10.7 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 EAX90292.1 - 0.18 12.4 1.3 0.34 11.6 1.3 1.4 1 0 0 1 1 1 0 SlyX DUF4200 PF13863.6 EAX90292.1 - 0.21 12.0 6.4 0.16 12.4 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) GrpE PF01025.19 EAX90292.1 - 0.36 10.5 4.8 0.52 10.0 4.8 1.3 1 0 0 1 1 1 0 GrpE SQAPI PF16845.5 EAX90293.1 - 7.2e-05 23.1 0.2 8.8e-05 22.8 0.2 1.0 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Cystatin PF00031.21 EAX90293.1 - 8.3e-05 22.8 0.2 0.0001 22.5 0.2 1.2 1 0 0 1 1 1 1 Cystatin domain DUF1642 PF07852.11 EAX90294.1 - 0.49 11.0 12.5 0.17 12.5 9.9 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) Ank_4 PF13637.6 EAX90295.1 - 9.1e-80 262.1 5.3 6.5e-13 48.9 0.0 9.7 2 1 9 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90295.1 - 1.1e-77 256.7 28.3 1.8e-16 60.5 0.4 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90295.1 - 5.4e-60 197.4 1.4 1.5e-07 31.6 0.0 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX90295.1 - 1.4e-56 187.8 15.5 4.2e-09 36.5 0.0 6.8 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90295.1 - 2.9e-56 180.8 0.3 4.4e-05 23.5 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat DUF3447 PF11929.8 EAX90295.1 - 5.2e-37 125.6 2.0 2.7e-36 123.3 2.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) 3Beta_HSD PF01073.19 EAX90295.1 - 6.7e-07 28.6 18.0 1.4 7.8 0.2 6.5 1 1 6 7 7 7 6 3-beta hydroxysteroid dehydrogenase/isomerase family PH_8 PF15409.6 EAX90295.1 - 2.9e-06 27.5 0.2 49 4.3 0.0 6.4 1 1 6 7 7 7 0 Pleckstrin homology domain PmrD PF11183.8 EAX90295.1 - 0.00016 21.7 0.2 0.6 10.3 0.0 4.1 1 1 2 4 4 4 1 Polymyxin resistance protein PmrD DUF502 PF04367.13 EAX90295.1 - 0.003 17.4 0.0 65 3.5 0.0 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF502) CbiK PF06180.11 EAX90295.1 - 0.011 15.0 2.1 14 4.8 0.1 4.4 1 1 5 6 6 6 0 Cobalt chelatase (CbiK) Apc13p PF05839.11 EAX90295.1 - 0.039 14.1 8.2 18 5.6 0.1 5.5 1 1 6 7 7 7 0 Apc13p protein DUF4106 PF13388.6 EAX90297.1 - 3.6e-267 886.3 44.6 2.7e-146 488.1 13.2 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX90297.1 - 0.0092 16.3 3.3 0.064 13.6 0.3 3.0 3 0 0 3 3 3 1 Kidney androgen-regulated DUF3447 PF11929.8 EAX90298.1 - 2.3e-14 53.1 0.7 2.3e-14 53.1 0.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) KIX PF02172.16 EAX90298.1 - 0.019 15.2 0.5 0.052 13.8 0.5 1.7 1 0 0 1 1 1 0 KIX domain Ank_2 PF12796.7 EAX90299.1 - 4.5e-36 123.3 21.2 1e-15 58.1 4.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90299.1 - 1.6e-32 111.4 5.5 3.9e-13 49.6 0.2 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX90299.1 - 2.6e-30 103.5 6.7 1.7e-07 31.4 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAX90299.1 - 2.1e-24 82.9 9.6 1e-05 25.5 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX90299.1 - 7.8e-18 64.3 11.8 2.1e-07 31.1 0.5 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90299.1 - 1.3e-17 63.5 2.2 1.3e-17 63.5 2.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) SAB PF04382.13 EAX90299.1 - 0.0052 16.8 0.1 17 5.6 0.0 3.4 1 1 2 3 3 3 1 SAB domain Toxin-JAB1 PF15659.6 EAX90299.1 - 0.16 12.3 4.2 0.16 12.4 1.2 2.0 1 1 1 2 2 2 0 JAB-like toxin 1 Ribosomal_L21e PF01157.18 EAX90300.1 - 2.3e-38 130.1 0.3 3.3e-38 129.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e TA0956 PF11513.8 EAX90301.1 - 0.058 13.6 1.5 5.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 USP7_C2 PF14533.6 EAX90302.1 - 0.036 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Atg14 PF10186.9 EAX90302.1 - 0.07 12.2 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2779 PF11074.8 EAX90302.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) YolD PF08863.10 EAX90303.1 - 0.68 10.0 7.6 2.1 8.4 0.1 3.1 2 2 2 4 4 4 0 YolD-like protein Snapin_Pallidin PF14712.6 EAX90303.1 - 3.3 8.2 9.1 1.3 9.5 4.9 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Vps51 PF08700.11 EAX90305.1 - 1.2e-09 38.1 0.3 1.2e-09 38.1 0.3 2.9 3 0 0 3 3 3 1 Vps51/Vps67 Mid2 PF04478.12 EAX90305.1 - 0.058 13.2 0.8 0.47 10.3 0.3 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor ACT_7 PF13840.6 EAX90306.1 - 0.092 12.6 0.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 ACT domain Ank PF00023.30 EAX90307.1 - 6.7e-56 184.4 12.6 6e-08 32.8 0.1 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_2 PF12796.7 EAX90307.1 - 1.5e-53 179.3 36.5 3.9e-14 53.0 3.8 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90307.1 - 8.5e-53 176.1 12.3 6.8e-10 39.3 0.0 9.3 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90307.1 - 7.2e-45 145.8 15.1 3.4e-05 23.9 0.1 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EAX90307.1 - 1.8e-43 146.0 25.1 1.5e-11 44.3 0.7 7.1 3 3 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90307.1 - 2.1e-37 126.9 4.7 2.1e-37 126.9 4.7 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) SAB PF04382.13 EAX90307.1 - 0.0021 18.1 1.1 1.5 9.0 0.0 4.6 5 0 0 5 5 5 1 SAB domain DUF3718 PF12514.8 EAX90307.1 - 0.042 14.0 5.8 24 5.2 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3718) DUF5119 PF17145.4 EAX90307.1 - 0.12 12.3 0.4 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) ComC PF03047.14 EAX90307.1 - 0.14 12.0 0.6 0.51 10.2 0.6 2.0 1 0 0 1 1 1 0 COMC family Cation_ATPase_N PF00690.26 EAX90308.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Sec1 PF00995.23 EAX90309.1 - 1.4e-54 186.4 0.0 1.7e-54 186.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HHH_4 PF14490.6 EAX90310.1 - 0.045 13.7 0.4 0.19 11.8 0.4 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Arylesterase PF01731.20 EAX90311.1 - 0.016 15.4 2.2 5.3 7.3 0.0 2.6 1 1 1 2 2 2 0 Arylesterase Tetraspanin PF00335.20 EAX90311.1 - 0.12 12.1 9.6 0.22 11.2 9.6 1.5 1 1 0 1 1 1 0 Tetraspanin family LRR_5 PF13306.6 EAX90312.1 - 2e-102 338.1 96.4 4.7e-26 91.3 12.8 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90312.1 - 2.7e-14 52.7 3.3 0.044 13.6 0.1 9.0 6 1 5 11 11 11 5 Leucine rich repeat MecA PF05389.12 EAX90312.1 - 0.00031 20.5 2.3 0.00059 19.5 2.3 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) FNIP PF05725.12 EAX90312.1 - 0.0011 19.1 4.5 2.4 8.4 0.1 6.5 6 1 0 6 6 6 1 FNIP Repeat TMP PF05017.14 EAX90314.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90315.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_5 PF13306.6 EAX90316.1 - 9.5e-147 481.4 81.7 3.3e-37 127.3 11.3 6.1 2 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90316.1 - 1.4e-30 104.8 0.0 0.009 15.8 0.0 11.2 3 2 9 12 12 12 10 Leucine rich repeat MtrG PF04210.13 EAX90316.1 - 0.0093 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit G DEC-1_N PF04625.13 EAX90316.1 - 2.2 7.2 7.1 3.2 6.6 7.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2448 PF10476.9 EAX90316.1 - 3.6 7.4 6.4 12 5.7 0.1 3.9 5 1 0 6 6 6 0 Protein of unknown function C-terminus (DUF2448) DUF4490 PF14892.6 EAX90317.1 - 8e-10 38.7 0.3 8.8e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Bac_rhamnosid_N PF08531.10 EAX90318.1 - 0.25 11.2 6.0 0.45 10.3 0.2 2.5 2 1 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain DUF3584 PF12128.8 EAX90318.1 - 0.26 8.7 47.0 0.4 8.2 47.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPOUT_MTase_2 PF14419.6 EAX90318.1 - 0.33 10.3 3.9 0.12 11.7 1.1 1.7 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Golgin_A5 PF09787.9 EAX90318.1 - 1.8 8.0 51.5 0.81 9.1 15.7 3.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 EAX90318.1 - 2 8.6 44.9 0.97 9.6 14.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_p24 PF05073.12 EAX90318.1 - 2.5 7.8 19.9 0.099 12.4 11.6 2.4 1 1 0 2 2 2 0 Baculovirus P24 capsid protein APG6_N PF17675.1 EAX90318.1 - 2.8 8.5 54.7 8.8 6.9 14.3 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 EAX90318.1 - 3.1 6.6 50.6 0.61 8.9 21.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 EAX90318.1 - 5.6 6.3 50.9 0.28 10.5 19.7 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EAX90318.1 - 7 6.1 48.1 21 4.6 22.4 2.9 1 1 2 3 3 3 0 Intermediate filament protein CLN3 PF02487.17 EAX90320.1 - 6.1e-28 98.0 13.9 8e-26 91.0 13.9 2.0 1 1 0 1 1 1 1 CLN3 protein FHA PF00498.26 EAX90322.1 - 5.5e-10 39.5 0.2 9.9e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 FHA domain ARPC4 PF05856.12 EAX90323.1 - 3.8e-68 228.3 4.1 4.2e-68 228.2 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.14 EAX90323.1 - 0.0038 17.0 0.8 0.026 14.2 0.8 1.9 1 1 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Brr6_like_C_C PF10104.9 EAX90323.1 - 0.0089 15.8 0.4 0.015 15.0 0.4 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ADIP PF11559.8 EAX90324.1 - 8.2e-08 32.5 15.2 8.2e-08 32.5 15.2 7.9 5 1 3 8 8 8 3 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EAX90324.1 - 0.0027 18.2 28.7 0.0027 18.2 28.7 6.5 3 2 3 6 6 6 2 Apg6 coiled-coil region Csm1_N PF18504.1 EAX90324.1 - 0.0096 16.2 3.5 0.0096 16.2 3.5 10.8 5 3 7 12 12 12 1 Csm1 N-terminal domain PRKG1_interact PF15898.5 EAX90324.1 - 0.015 16.2 16.9 0.015 16.2 16.9 9.0 5 3 3 9 9 9 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 EAX90324.1 - 0.016 15.3 2.9 0.016 15.3 2.9 10.0 6 3 4 10 10 10 0 bZIP transcription factor TSC22 PF01166.18 EAX90324.1 - 0.042 14.2 0.7 0.042 14.2 0.7 7.7 6 2 2 8 8 8 0 TSC-22/dip/bun family IclR PF01614.18 EAX90324.1 - 9.2 6.1 10.4 9.8 6.0 2.0 3.5 2 1 0 2 2 2 0 Bacterial transcriptional regulator PQ-loop PF04193.14 EAX90328.1 - 6.4 6.6 17.2 0.58 10.0 0.6 3.6 4 0 0 4 4 4 0 PQ loop repeat DUF4107 PF13389.6 EAX90331.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX90332.1 - 0.0023 17.6 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase RRM_1 PF00076.22 EAX90336.1 - 4.6e-67 221.8 7.2 5.1e-16 58.3 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX90336.1 - 1.9e-09 37.5 0.7 0.056 13.6 0.0 4.6 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EAX90336.1 - 2.9e-09 36.8 1.8 0.029 14.4 0.0 4.5 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX90336.1 - 1.8e-08 34.3 5.2 0.012 15.6 0.0 4.7 3 1 1 4 4 4 2 RNA binding motif RRM_occluded PF16842.5 EAX90336.1 - 9.8e-07 28.6 0.0 0.2 11.5 0.0 4.0 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EAX90336.1 - 0.0019 17.8 0.0 4.1 7.0 0.1 3.5 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAX90336.1 - 0.0028 17.7 0.2 7.3 6.7 0.1 3.8 2 1 1 3 3 3 1 Limkain b1 DUF4651 PF15513.6 EAX90336.1 - 0.0078 16.0 0.3 3.7 7.4 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4651) SET_assoc PF11767.8 EAX90336.1 - 0.032 13.9 0.1 25 4.6 0.0 3.9 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 EAX90336.1 - 0.1 12.8 6.8 5.5 7.2 0.4 3.6 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter RNA_bind PF08675.11 EAX90336.1 - 0.13 12.3 0.3 17 5.5 0.1 3.7 4 0 0 4 4 4 0 RNA binding domain Peptidase_C13 PF01650.18 EAX90337.1 - 3.6e-84 282.3 0.5 5.4e-84 281.7 0.5 1.2 1 0 0 1 1 1 1 Peptidase C13 family Thioredoxin PF00085.20 EAX90338.1 - 1.4e-21 76.4 0.0 1.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX90338.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX90338.1 - 0.0021 18.5 0.1 0.024 15.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EAX90338.1 - 0.005 16.7 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EAX90338.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 EAX90338.1 - 0.031 14.7 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 EAX90338.1 - 0.08 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Ank_2 PF12796.7 EAX90339.1 - 6e-14 52.4 0.6 2.4e-10 40.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90339.1 - 1.1e-11 44.7 0.5 3.8e-07 30.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90339.1 - 1.6e-10 40.2 0.8 0.027 15.0 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAX90339.1 - 2.5e-10 40.7 0.5 0.00012 22.6 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90339.1 - 0.00021 21.2 3.8 0.00021 21.2 3.8 3.4 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX90339.1 - 0.0027 18.1 0.1 3.1 8.4 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat FYVE PF01363.21 EAX90340.1 - 3.6e-18 65.5 8.7 9.5e-18 64.1 8.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EAX90340.1 - 0.0037 17.8 0.5 0.0093 16.5 0.1 1.9 2 0 0 2 2 2 1 PH domain zf-CW PF07496.15 EAX90340.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger GF_recep_IV PF14843.6 EAX90340.1 - 0.12 12.2 9.1 0.096 12.5 5.3 2.4 3 0 0 3 3 3 0 Growth factor receptor domain IV DUF2924 PF11149.8 EAX90341.1 - 0.63 10.4 4.8 2 8.8 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Connexin PF00029.19 EAX90342.1 - 0.045 13.5 5.8 0.071 12.9 5.8 1.4 1 0 0 1 1 1 0 Connexin NARP1 PF12569.8 EAX90342.1 - 0.067 12.1 13.9 0.089 11.7 13.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.15 EAX90342.1 - 0.24 10.3 1.6 0.35 9.7 1.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) ETRAMP PF09716.10 EAX90342.1 - 2.3 8.3 4.5 3.4 7.8 4.1 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Connexin PF00029.19 EAX90343.1 - 0.15 11.8 2.6 0.24 11.2 2.6 1.4 1 0 0 1 1 1 0 Connexin ETRAMP PF09716.10 EAX90343.1 - 0.21 11.7 3.1 0.39 10.8 3.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Rtf2 PF04641.12 EAX90343.1 - 0.56 9.5 11.0 0.81 9.0 11.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Serinc PF03348.15 EAX90343.1 - 1 8.2 2.9 1.5 7.7 2.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1168 PF06658.12 EAX90343.1 - 1.2 9.0 17.2 2.5 7.9 17.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SR-25 PF10500.9 EAX90343.1 - 3.4 7.2 14.1 5.4 6.6 14.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Totivirus_coat PF05518.11 EAX90343.1 - 4.9 5.1 13.4 6.5 4.7 13.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_S49_N PF08496.10 EAX90343.1 - 5.2 7.1 10.9 7.3 6.6 10.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YmaF PF12788.7 EAX90344.1 - 0.19 12.3 1.5 11 6.6 0.1 2.1 1 1 0 2 2 2 0 YmaF family Tubulin PF00091.25 EAX90348.1 - 1.3e-28 100.6 0.0 1.5e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EAX90348.1 - 5.6e-07 29.9 0.0 7.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_C PF03953.17 EAX90349.1 - 6.3e-33 113.6 0.0 1.2e-32 112.7 0.0 1.5 1 1 0 1 1 1 1 Tubulin C-terminal domain DnaA_N PF11638.8 EAX90349.1 - 0.045 13.5 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 DnaA N-terminal domain Tubulin PF00091.25 EAX90349.1 - 0.053 13.7 0.1 0.097 12.9 0.1 1.5 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Nitrate_red_gam PF02665.14 EAX90349.1 - 0.062 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Ank_2 PF12796.7 EAX90351.1 - 2e-34 118.0 1.5 2e-13 50.7 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90351.1 - 3.8e-34 116.6 3.6 4.8e-10 39.8 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90351.1 - 5.9e-31 106.1 0.3 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90351.1 - 1.9e-26 89.2 1.2 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX90351.1 - 8.1e-24 83.0 2.6 0.00026 21.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX90351.1 - 0.0035 17.3 0.7 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) GPS2_interact PF15784.5 EAX90352.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX90352.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX90353.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX90353.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX90354.1 - 0.0074 16.3 0.2 0.0088 16.0 0.2 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta CREPT PF16566.5 EAX90357.1 - 0.047 13.9 1.0 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX90357.1 - 0.084 12.9 0.7 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus L27_1 PF09058.10 EAX90357.1 - 0.12 12.4 2.5 2.5 8.2 0.0 2.9 3 0 0 3 3 3 0 L27_1 Fib_alpha PF08702.10 EAX90357.1 - 0.61 10.3 6.7 0.47 10.6 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rrf2 PF02082.20 EAX90358.1 - 0.022 15.1 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DDE_1 PF03184.19 EAX90359.1 - 1.1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease UvrC_HhH_N PF08459.11 EAX90359.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF2767 PF10965.8 EAX90360.1 - 0.013 15.4 0.2 0.032 14.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) CLZ PF16526.5 EAX90360.1 - 0.015 15.7 8.2 0.14 12.5 4.1 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3347 PF11827.8 EAX90360.1 - 0.022 15.0 5.6 0.026 14.7 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Paralemmin PF03285.15 EAX90360.1 - 0.053 13.1 7.3 0.057 13.0 7.3 1.0 1 0 0 1 1 1 0 Paralemmin DASH_Hsk3 PF08227.11 EAX90360.1 - 0.057 13.8 0.9 0.099 13.0 0.9 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like BST2 PF16716.5 EAX90360.1 - 0.057 14.0 3.9 0.057 14.0 3.9 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 L31 PF09784.9 EAX90360.1 - 0.1 13.0 4.9 0.17 12.3 4.9 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4349 PF14257.6 EAX90360.1 - 0.14 11.5 5.0 0.17 11.3 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PspA_IM30 PF04012.12 EAX90360.1 - 0.19 11.3 8.8 0.24 11.0 8.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF724 PF05266.14 EAX90360.1 - 0.23 11.2 10.1 0.26 11.1 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EAX90360.1 - 0.27 11.3 5.7 0.33 11.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 EAX90360.1 - 0.43 10.3 4.7 0.47 10.2 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 EAX90360.1 - 0.58 9.7 8.6 0.6 9.6 8.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bcr-Abl_Oligo PF09036.10 EAX90360.1 - 1 9.4 5.5 1.6 8.8 2.2 2.5 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain TRAF_BIRC3_bd PF16673.5 EAX90360.1 - 2.9 7.8 7.8 0.52 10.2 1.0 2.6 1 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain FapA PF03961.13 EAX90360.1 - 5.6 5.4 10.7 6.2 5.3 10.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 EAX90360.1 - 7 6.6 11.6 1.8 8.5 4.4 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Myb_DNA-binding PF00249.31 EAX90361.1 - 2.6e-23 81.9 4.3 4.3e-12 46.0 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90361.1 - 7e-20 71.0 6.9 2.7e-12 46.8 2.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90361.1 - 0.00095 19.2 2.0 0.46 10.5 0.3 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX90361.1 - 0.0091 15.9 1.4 0.0091 15.9 1.4 2.2 1 1 2 3 3 3 1 Myb DNA-binding like DUF4167 PF13763.6 EAX90361.1 - 0.012 15.8 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) SANT_DAMP1_like PF16282.5 EAX90361.1 - 0.04 14.1 1.0 0.11 12.7 1.0 1.8 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF4199 PF13858.6 EAX90362.1 - 0.0024 18.3 2.0 0.0053 17.2 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF2207 PF09972.9 EAX90362.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 EAX90362.1 - 0.16 12.0 0.4 0.16 12.0 0.4 3.1 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2976 PF11190.8 EAX90362.1 - 0.25 11.1 1.1 0.64 9.9 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) LptF_LptG PF03739.14 EAX90362.1 - 0.62 8.9 2.7 1.2 8.0 2.7 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4064 PF13273.6 EAX90362.1 - 0.67 10.3 5.2 2.1 8.7 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Jiraiya PF15038.6 EAX90362.1 - 7.2 6.0 6.8 0.82 9.1 1.5 1.8 1 1 1 2 2 2 0 Jiraiya Myb_DNA-binding PF00249.31 EAX90365.1 - 9.6e-28 96.1 0.6 1.3e-13 50.9 0.1 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90365.1 - 2.4e-20 72.5 0.2 1.3e-13 50.9 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90365.1 - 0.00016 21.7 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX90365.1 - 0.0041 17.0 0.2 0.76 9.7 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX90365.1 - 0.2 12.1 3.2 8.8 6.8 0.4 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain COPIIcoated_ERV PF07970.12 EAX90366.1 - 3.9e-29 102.1 2.9 8.4e-29 101.0 2.9 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX90366.1 - 4.7e-22 78.1 0.0 9.5e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) YBD PF17725.1 EAX90366.1 - 0.085 12.7 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 YAP binding domain Ferric_reduct PF01794.19 EAX90367.1 - 3.9e-05 23.8 4.5 0.023 14.8 0.1 2.5 2 1 0 2 2 2 2 Ferric reductase like transmembrane component DUF898 PF05987.13 EAX90367.1 - 0.0011 18.1 3.7 0.092 11.8 3.8 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) EI24 PF07264.11 EAX90367.1 - 0.0067 16.7 2.8 0.0067 16.7 2.8 1.9 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF4064 PF13273.6 EAX90367.1 - 0.039 14.2 14.0 2.4 8.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Piezo_RRas_bdg PF12166.8 EAX90367.1 - 0.087 12.1 3.4 0.3 10.3 0.7 2.2 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain GWT1 PF06423.12 EAX90367.1 - 0.11 12.6 6.4 0.051 13.7 3.3 1.9 2 0 0 2 2 2 0 GWT1 PDR_CDR PF06422.12 EAX90367.1 - 0.25 11.3 3.5 0.34 10.9 2.1 2.0 1 1 0 1 1 1 0 CDR ABC transporter DUF3309 PF11752.8 EAX90367.1 - 1.7 8.8 11.2 0.98 9.5 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF1449 PF07290.11 EAX90367.1 - 3.9 7.1 7.7 0.21 11.2 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Guanylate_cyc PF00211.20 EAX90369.1 - 1.5e-42 145.3 0.1 3.9e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LrgB PF04172.16 EAX90369.1 - 0.017 14.6 1.2 0.048 13.2 1.2 1.7 1 0 0 1 1 1 0 LrgB-like family PAS_8 PF13188.7 EAX90369.1 - 0.02 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 EAX90369.1 - 0.11 12.7 0.6 0.42 10.9 0.2 2.2 2 0 0 2 2 2 0 PAS domain Myb_DNA-binding PF00249.31 EAX90370.1 - 3.9e-19 68.6 0.0 1.5e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90370.1 - 1.5e-15 57.1 1.4 2.7e-09 37.1 0.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain KIAA1430 PF13879.6 EAX90371.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX90372.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DNA_pol_B_2 PF03175.13 EAX90373.1 - 4.1e-10 39.1 3.4 4.1e-10 39.1 3.4 2.4 1 1 2 3 3 3 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX90373.1 - 0.11 12.1 0.7 0.23 11.0 0.7 1.5 1 1 0 1 1 1 0 Isy1-like splicing family PHM7_cyt PF14703.6 EAX90373.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TMP PF05017.14 EAX90376.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90377.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ribosomal_L26 PF16906.5 EAX90378.1 - 8.6e-29 99.8 2.5 1.1e-28 99.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EAX90378.1 - 9.1e-06 25.4 0.3 2e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 KOW motif DUF3447 PF11929.8 EAX90380.1 - 1.6e-39 133.7 6.4 1.6e-39 133.7 6.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90380.1 - 0.00029 21.4 0.1 0.012 16.2 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90380.1 - 0.0056 17.2 0.2 10 6.8 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90380.1 - 0.016 15.7 0.3 90 4.2 0.1 4.2 3 0 0 3 3 3 0 Ankyrin repeat Zn-ribbon_8 PF09723.10 EAX90381.1 - 1.9e-05 24.7 0.6 4.5e-05 23.5 0.6 1.6 1 0 0 1 1 1 1 Zinc ribbon domain TFIIE_alpha PF02002.17 EAX90381.1 - 0.0002 21.1 2.4 0.0002 21.1 2.4 2.1 2 1 0 2 2 2 1 TFIIE alpha subunit HypA PF01155.19 EAX90381.1 - 0.004 17.2 0.9 0.013 15.5 0.9 2.0 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 EAX90381.1 - 0.0092 16.4 0.4 0.028 14.9 0.4 1.8 1 0 0 1 1 1 1 Cytochrome c3 HTH_Mga PF08280.11 EAX90381.1 - 0.01 15.9 0.2 0.076 13.1 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DUF1610 PF07754.11 EAX90381.1 - 0.03 14.3 0.9 0.064 13.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Sigma70_r4 PF04545.16 EAX90381.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 zinc_ribbon_10 PF10058.9 EAX90381.1 - 0.046 13.4 2.2 0.1 12.3 2.2 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 EAX90381.1 - 0.17 11.4 3.8 0.57 9.7 3.8 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding zf-AN1 PF01428.16 EAX90381.1 - 0.19 11.9 4.1 2.4 8.4 1.2 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger FDF PF09532.10 EAX90381.1 - 0.2 12.5 5.8 0.45 11.4 5.8 1.7 1 1 0 1 1 1 0 FDF domain zf-RING_7 PF02591.15 EAX90381.1 - 0.27 11.5 2.2 1.4 9.2 2.3 2.3 1 1 0 1 1 1 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 EAX90381.1 - 0.36 10.8 2.9 1.9 8.4 2.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EAX90381.1 - 0.41 10.6 2.4 2.2 8.3 0.7 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 EAX90381.1 - 4.2 8.5 5.7 32 5.7 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ADIP PF11559.8 EAX90382.1 - 0.29 11.2 103.2 0.094 12.8 5.5 7.4 2 2 5 8 8 8 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 EAX90382.1 - 1.1 7.7 12.8 3 6.3 1.0 2.5 1 1 2 3 3 3 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 EAX90382.1 - 1.6 8.5 112.5 0.33 10.8 27.0 6.4 2 1 5 7 7 7 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EAX90382.1 - 4.8 6.0 100.7 0.02 13.8 19.2 5.2 1 1 4 5 5 5 0 Spc7 kinetochore protein APG6_N PF17675.1 EAX90382.1 - 8 7.0 98.2 0.13 12.8 13.5 6.4 1 1 4 6 6 6 0 Apg6 coiled-coil region DUF3447 PF11929.8 EAX90383.1 - 4.1e-39 132.4 6.6 1.8e-38 130.3 6.6 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX90383.1 - 3e-38 129.7 3.0 2.6e-08 34.2 0.0 7.5 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX90383.1 - 8.6e-38 127.2 2.7 9.8e-07 29.0 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 EAX90383.1 - 6.5e-33 113.2 14.9 1.2e-14 54.6 1.3 4.9 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90383.1 - 9.8e-29 99.1 10.0 3.6e-08 33.5 0.1 5.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90383.1 - 2.5e-27 91.9 4.6 7.1e-05 22.9 0.1 8.4 8 0 0 8 8 8 5 Ankyrin repeat DUF3718 PF12514.8 EAX90383.1 - 0.047 13.8 1.1 31 4.8 0.0 4.9 4 2 2 6 6 6 0 Protein of unknown function (DUF3718) FliE PF02049.18 EAX90383.1 - 0.75 10.0 3.2 10 6.4 0.4 3.0 1 1 3 4 4 4 0 Flagellar hook-basal body complex protein FliE Mucin_bdg PF03272.13 EAX90383.1 - 1.4 9.0 9.6 19 5.3 0.1 4.4 2 1 3 5 5 5 0 Putative mucin or carbohydrate-binding module Ank_2 PF12796.7 EAX90384.1 - 5.5e-61 203.1 27.4 7.6e-13 48.9 0.7 7.2 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90384.1 - 7.3e-60 198.6 19.7 4.2e-11 43.1 0.2 11.1 5 2 7 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX90384.1 - 7.8e-57 187.4 11.2 1.4e-06 28.5 0.0 10.9 10 1 1 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 EAX90384.1 - 5.6e-49 158.4 14.0 7.5e-05 22.8 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EAX90384.1 - 1e-47 159.6 12.4 1.9e-11 44.0 0.1 7.2 4 1 3 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90384.1 - 1.2e-35 121.3 4.2 1.2e-35 121.3 4.2 4.0 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX90384.1 - 0.021 15.0 0.3 19 5.5 0.0 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF3718) DHBP_synthase PF00926.19 EAX90384.1 - 0.048 13.2 0.2 8.5 5.9 0.0 2.9 1 1 2 3 3 3 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Phage_TAC_12 PF12363.8 EAX90385.1 - 0.036 14.5 0.2 0.22 12.0 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DUF1126 PF06565.12 EAX90386.1 - 7.3e-19 67.5 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain PSP PF04046.16 EAX90388.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90389.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3447 PF11929.8 EAX90391.1 - 8.1e-08 32.1 0.2 8.1e-08 32.1 0.2 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90392.1 - 1.3e-88 291.6 56.0 2.5e-16 60.0 3.9 8.4 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90392.1 - 5.8e-77 253.2 27.2 8.2e-11 42.2 0.2 14.5 2 2 14 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90392.1 - 7e-72 236.6 23.1 1.7e-12 47.3 0.4 11.5 6 4 5 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX90392.1 - 1e-70 231.3 25.2 0.00021 21.6 0.0 16.2 16 0 0 16 16 16 13 Ankyrin repeat Ank_3 PF13606.6 EAX90392.1 - 5e-64 204.7 32.1 0.0001 22.4 0.1 16.5 16 0 0 16 16 16 14 Ankyrin repeat SQAPI PF16845.5 EAX90392.1 - 0.0094 16.3 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Alpha_adaptin_C PF02296.16 EAX90392.1 - 0.02 15.1 0.2 2 8.6 0.1 2.9 1 1 1 2 2 2 0 Alpha adaptin AP2, C-terminal domain Peptidase_M16 PF00675.20 EAX90392.1 - 0.029 14.4 0.6 41 4.1 0.0 4.8 4 3 2 6 6 6 0 Insulinase (Peptidase family M16) CCDC84 PF14968.6 EAX90392.1 - 0.035 13.7 1.0 1.5 8.4 0.0 2.5 1 1 0 2 2 2 0 Coiled coil protein 84 UCH PF00443.29 EAX90393.1 - 7e-50 169.9 1.9 7e-50 169.9 1.9 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX90393.1 - 2.4e-09 37.2 4.2 2.4e-05 24.1 0.2 3.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Stk19 PF10494.9 EAX90393.1 - 0.042 13.5 3.5 0.8 9.3 0.4 2.8 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 ImcF-related_N PF14331.6 EAX90393.1 - 0.051 12.9 0.2 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 ImcF-related N-terminal domain PsbQ PF05757.11 EAX90393.1 - 0.85 9.3 4.2 55 3.4 0.0 3.7 4 0 0 4 4 4 0 Oxygen evolving enhancer protein 3 (PsbQ) PYRIN PF02758.16 EAX90393.1 - 1.2 9.3 8.7 9.6 6.4 0.8 4.8 5 0 0 5 5 5 0 PAAD/DAPIN/Pyrin domain Gly_rich PF12810.7 EAX90394.1 - 2.3e-07 31.0 11.7 2.4e-07 30.9 11.7 1.0 1 0 0 1 1 1 1 Glycine rich protein PTR PF12789.7 EAX90395.1 - 3.9e-16 58.8 2.1 3.9e-16 58.8 2.1 3.0 4 0 0 4 4 4 2 Phage tail repeat like DUF3839 PF12943.7 EAX90396.1 - 4.3e-50 170.4 1.8 6.7e-50 169.8 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF4490 PF14892.6 EAX90396.1 - 0.24 11.4 2.1 0.46 10.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4490) NBD94 PF16830.5 EAX90396.1 - 1.1 9.7 5.7 3.3 8.2 0.8 2.7 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH DUF3839 PF12943.7 EAX90397.1 - 7.6e-80 267.8 10.4 9.7e-80 267.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX90398.1 - 1.9e-06 28.3 0.0 4.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX90398.1 - 0.0049 16.7 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain EF-hand_10 PF14788.6 EAX90400.1 - 0.0017 18.2 0.1 0.0035 17.2 0.1 1.5 1 0 0 1 1 1 1 EF hand DUF790 PF05626.11 EAX90400.1 - 0.14 10.9 3.0 0.48 9.1 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF790) DUF3839 PF12943.7 EAX90401.1 - 1.6e-153 509.1 12.3 2e-153 508.8 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX90401.1 - 0.006 15.8 0.0 0.033 13.4 0.0 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region PA28_beta PF02252.18 EAX90401.1 - 0.028 14.1 2.8 0.068 12.9 0.3 2.7 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX90401.1 - 0.14 12.7 3.4 2.6 8.6 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX90401.1 - 0.32 11.5 3.8 0.34 11.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) HCBP_related PF06594.11 EAX90402.1 - 0.11 12.4 0.0 1.4e+02 2.5 0.0 3.7 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain Chordopox_A30L PF06015.12 EAX90402.1 - 0.67 9.8 5.4 11 5.9 0.3 2.4 1 1 2 3 3 3 0 Chordopoxvirus A30L protein Amidase02_C PF12123.8 EAX90404.1 - 0.034 13.8 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX90405.1 - 2.6e-70 235.8 2.7 3.7e-70 235.3 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX90406.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pro-NT_NN PF07421.11 EAX90407.1 - 0.025 14.8 0.1 0.025 14.8 0.1 1.0 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Tctex-1 PF03645.13 EAX90409.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Tctex-1 family PMT_2 PF13231.6 EAX90410.1 - 0.012 15.8 5.1 0.012 15.8 5.1 3.8 3 2 1 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Peptidase_M50B PF13398.6 EAX90410.1 - 3.2 7.3 17.2 4.6 6.8 5.2 2.5 2 1 0 2 2 2 0 Peptidase M50B-like UPF0160 PF03690.13 EAX90412.1 - 2.2e-97 326.6 0.0 2.4e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF4191 PF13829.6 EAX90413.1 - 0.024 14.0 0.6 0.024 14.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2663 PF10864.8 EAX90413.1 - 8.3 6.8 13.1 0.11 12.9 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) DUF4476 PF14771.6 EAX90414.1 - 0.0021 18.3 0.4 0.0028 17.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Antimicrobial11 PF08106.11 EAX90414.1 - 0.1 12.7 0.3 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 Formaecin family Pox_A32 PF04665.12 EAX90416.1 - 3.4e-08 33.2 1.2 4.2e-08 33.0 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX90416.1 - 0.0027 17.4 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX90416.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX90416.1 - 0.09 12.8 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAX90418.1 - 5.1e-34 116.5 0.1 5.1e-34 116.5 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX90418.1 - 0.0013 18.8 0.1 0.004 17.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX90418.1 - 0.0084 16.5 5.0 0.27 11.7 1.1 2.5 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 DBR1 PF05011.13 EAX90418.1 - 1.6 9.2 5.9 0.44 11.0 1.7 2.1 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain T5orf172 PF10544.9 EAX90419.1 - 9.6e-07 29.3 0.1 2.4e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX90419.1 - 0.088 12.7 0.3 0.55 10.1 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX90420.1 - 2.2e-156 518.4 14.8 2.8e-156 518.1 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX90420.1 - 0.091 12.6 1.9 0.2 11.5 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX90420.1 - 2.3 8.7 6.8 3.9 8.0 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX90422.1 - 8.7e-18 64.1 2.4 8.7e-18 64.1 2.4 4.4 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX90422.1 - 0.05 13.3 0.2 0.37 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX90422.1 - 0.15 12.0 2.5 2.4 8.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Lectin_N PF03954.14 EAX90424.1 - 1.3 8.8 10.3 0.09 12.5 4.2 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Symplekin_C PF12295.8 EAX90425.1 - 0.14 12.2 3.1 0.24 11.4 0.3 2.6 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal TPR_2 PF07719.17 EAX90425.1 - 0.89 9.8 2.9 6.5 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TcdB_N PF12918.7 EAX90426.1 - 0.1 12.9 1.0 0.33 11.3 0.5 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NES_C_h PF18208.1 EAX90426.1 - 0.38 11.0 3.2 2 8.7 0.1 3.2 3 0 0 3 3 3 0 Nicking enzyme C-terminal middle helical domain CLU PF13236.6 EAX90427.1 - 3.6e-25 89.1 0.8 1.8e-24 86.8 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 EAX90427.1 - 2.2e-11 44.1 0.1 9.4e-10 38.8 0.0 2.9 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 DUF3911 PF13050.6 EAX90427.1 - 1.4 9.0 3.5 51 4.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3911) Ank_2 PF12796.7 EAX90428.1 - 2.7e-45 152.9 10.9 3.4e-15 56.4 0.5 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90428.1 - 6.9e-38 128.6 5.0 1.1e-08 35.4 0.1 6.4 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90428.1 - 3e-33 113.5 10.5 2e-08 34.3 0.2 7.6 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90428.1 - 2.3e-30 101.2 6.0 0.00071 19.8 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 EAX90428.1 - 1.3e-29 101.2 6.2 0.02 15.4 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat B5 PF03484.15 EAX90428.1 - 0.00048 20.4 0.1 4 7.8 0.0 3.9 1 1 2 3 3 3 2 tRNA synthetase B5 domain Fib_alpha PF08702.10 EAX90428.1 - 0.046 13.9 0.8 0.17 12.1 0.8 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_M16 PF00675.20 EAX90428.1 - 0.082 12.9 0.4 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) DUF3839 PF12943.7 EAX90429.1 - 1.8e-154 512.2 13.4 2.3e-154 511.8 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX90429.1 - 0.034 14.4 0.5 1.9 8.8 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX90429.1 - 0.16 11.8 1.4 0.5 10.2 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX90429.1 - 0.28 11.7 3.9 5.1 7.6 0.1 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mst1_SARAH PF11629.8 EAX90430.1 - 0.082 13.0 0.5 16 5.7 0.0 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Muted PF14942.6 EAX90430.1 - 0.12 12.7 0.8 14 6.0 0.1 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Rsa3 PF14615.6 EAX90430.1 - 0.73 9.4 3.6 16 5.1 0.3 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 PTR PF12789.7 EAX90431.1 - 5.2e-46 154.5 41.5 2.4e-23 81.9 7.8 6.1 6 1 0 6 6 6 3 Phage tail repeat like DUF5327 PF17261.2 EAX90431.1 - 0.022 15.5 3.0 5 7.9 0.5 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5327) DUF4116 PF13475.6 EAX90431.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Halogen_Hydrol PF10112.9 EAX90431.1 - 0.13 12.2 3.5 4.7 7.2 0.7 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PH_TFIIH PF08567.11 EAX90431.1 - 0.81 10.1 4.3 45 4.5 0.2 3.7 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain HIP1_clath_bdg PF16515.5 EAX90431.1 - 5.2 7.7 10.8 25 5.5 0.9 3.7 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CppA_C PF14507.6 EAX90431.1 - 9.3 7.0 8.5 2.5 8.9 0.3 3.5 4 0 0 4 4 4 0 CppA C-terminal DUF1493 PF07377.12 EAX90432.1 - 0.032 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX90433.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90434.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Copine PF07002.16 EAX90435.1 - 4.2e-71 238.8 0.0 5.8e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EAX90435.1 - 1.3e-17 64.0 0.5 1.8e-12 47.4 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EAX90435.1 - 0.00054 20.1 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus Metallophos PF00149.28 EAX90436.1 - 9.9e-25 88.2 0.4 1.4e-24 87.7 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX90436.1 - 0.0033 17.8 0.4 0.008 16.6 0.4 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX90436.1 - 0.0045 17.2 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EAX90437.1 - 1.1e-34 120.1 0.8 1.5e-34 119.6 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90437.1 - 1.5e-14 53.9 0.2 2e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX90437.1 - 0.00018 20.9 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX90437.1 - 0.0063 15.9 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX90437.1 - 0.0097 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Ras PF00071.22 EAX90439.1 - 4.7e-45 153.1 0.1 5.6e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90439.1 - 3.3e-30 104.8 0.1 5.3e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90439.1 - 6.4e-17 61.5 0.0 7.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX90439.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX90439.1 - 0.00048 19.5 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX90439.1 - 0.00078 19.2 0.2 0.034 13.9 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EAX90439.1 - 0.0011 18.9 0.5 0.023 14.6 0.5 2.3 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX90439.1 - 0.0026 17.4 0.2 0.045 13.3 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAX90439.1 - 0.011 16.1 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EAX90439.1 - 0.012 15.1 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX90439.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX90439.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAX90439.1 - 0.027 14.7 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX90439.1 - 0.027 15.0 0.1 0.047 14.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EAX90439.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 EAX90439.1 - 0.043 13.3 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PRA-PH PF01503.17 EAX90440.1 - 0.2 12.1 1.9 12 6.5 2.8 2.7 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4107 PF13389.6 EAX90441.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX90441.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX90442.1 - 0.074 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF2573 PF10835.8 EAX90444.1 - 0.00016 22.0 3.0 17 5.8 0.0 4.7 1 1 4 5 5 5 3 Protein of unknown function (DUF2573) Keratin_B2_2 PF13885.6 EAX90444.1 - 0.0005 20.0 24.7 0.041 13.8 7.2 3.1 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein FRG PF08867.11 EAX90444.1 - 0.011 16.6 3.8 11 7.0 0.1 3.1 1 1 2 3 3 3 0 FRG domain RHS PF03527.14 EAX90444.1 - 0.032 14.0 2.3 38 4.1 0.1 3.2 3 0 0 3 3 3 0 RHS protein TAL_effector PF03377.13 EAX90444.1 - 0.19 12.1 4.4 3.5e+02 1.6 0.0 6.0 5 4 2 7 7 7 0 TAL effector repeat CelTOS PF18659.1 EAX90445.1 - 0.011 16.2 3.5 0.016 15.7 3.5 1.2 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites mCpol PF18182.1 EAX90445.1 - 0.011 16.0 0.4 0.014 15.7 0.4 1.4 1 0 0 1 1 1 0 minimal CRISPR polymerase domain NDC10_II PF16787.5 EAX90445.1 - 0.016 14.3 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF919 PF06034.11 EAX90446.1 - 0.062 13.1 0.8 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DegQ PF08181.11 EAX90449.1 - 0.036 14.2 2.3 0.069 13.3 2.3 1.6 1 1 0 1 1 1 0 DegQ (SacQ) family Tnp_22_trimer PF17489.2 EAX90449.1 - 0.62 10.1 5.0 0.57 10.2 2.5 2.1 1 1 1 2 2 2 0 L1 transposable element trimerization domain NAD_binding_9 PF13454.6 EAX90452.1 - 0.03 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Styelin PF17562.2 EAX90452.1 - 0.09 13.2 0.1 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 Styelin Csm2_III-A PF03750.13 EAX90452.1 - 0.14 13.0 1.4 0.4 11.5 0.4 2.0 2 0 0 2 2 2 0 Csm2 Type III-A DDR PF08841.10 EAX90454.1 - 0.11 11.4 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX90455.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gly-zipper_Omp PF13488.6 EAX90457.1 - 0.0068 16.4 9.0 0.01 15.8 9.0 1.3 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX90457.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX90457.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX90457.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX90457.1 - 3 8.9 0.2 3 8.9 0.2 3.3 4 0 0 4 4 4 0 TMP repeat zf-U1 PF06220.12 EAX90458.1 - 3e-11 42.9 5.6 4.1e-11 42.4 5.6 1.2 1 0 0 1 1 1 1 U1 zinc finger RICTOR_M PF14666.6 EAX90459.1 - 1.5e-08 34.3 0.1 2.1e-06 27.4 0.0 3.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 EAX90459.1 - 1.2e-06 27.8 0.0 6.1e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EAX90459.1 - 0.074 13.5 1.0 0.19 12.1 0.1 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3431 PF11913.8 EAX90459.1 - 0.12 12.1 2.1 1.7 8.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) Ank_4 PF13637.6 EAX90460.1 - 3.7e-32 110.3 6.2 3.3e-08 33.9 0.0 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX90460.1 - 5.6e-26 89.8 8.9 2.4e-06 27.7 0.0 7.4 6 2 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX90460.1 - 3.5e-22 78.8 7.7 1.3e-10 41.8 0.2 3.8 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90460.1 - 1.4e-19 68.1 6.5 0.0022 18.3 0.1 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX90460.1 - 1.9e-19 69.4 1.3 1.2e-08 35.1 0.1 3.7 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Arg_repressor PF01316.21 EAX90460.1 - 0.025 14.3 1.0 40 4.0 0.0 4.3 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain DUF3447 PF11929.8 EAX90460.1 - 0.082 12.9 7.9 0.17 11.9 0.8 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF3447) Spy1 PF11357.8 EAX90460.1 - 0.32 11.3 2.2 0.62 10.4 0.6 2.0 2 0 0 2 2 2 0 Cell cycle regulatory protein MatE PF01554.18 EAX90461.1 - 7.9e-30 103.6 25.8 9.6e-16 57.9 8.2 2.9 3 1 0 3 3 3 2 MatE Myc_target_1 PF15179.6 EAX90461.1 - 0.18 11.7 1.1 0.41 10.5 0.3 2.1 2 1 1 3 3 3 0 Myc target protein 1 PSP PF04046.16 EAX90463.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90464.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Guanylate_cyc PF00211.20 EAX90466.1 - 3.3e-14 52.9 0.2 7.6e-14 51.7 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Cadherin_C_2 PF16492.5 EAX90468.1 - 0.002 18.8 1.6 0.0039 17.9 1.6 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal TcdA_TcdB_pore PF12920.7 EAX90468.1 - 0.13 10.5 1.6 0.51 8.5 0.3 1.9 1 1 1 2 2 2 0 TcdA/TcdB pore forming domain LRR_5 PF13306.6 EAX90469.1 - 4.4e-89 295.0 65.7 3.6e-33 114.3 16.7 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90469.1 - 5e-11 42.2 2.1 0.2 11.5 0.2 6.2 2 2 4 6 6 6 4 Leucine rich repeat P_proprotein PF01483.20 EAX90469.1 - 2.9e-05 24.0 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Methyltransf_11 PF08241.12 EAX90471.1 - 6.3e-10 39.6 0.0 9.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX90471.1 - 1.1e-09 38.9 0.0 1.7e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX90471.1 - 2.2e-09 37.4 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX90471.1 - 6.2e-09 36.4 0.0 1.2e-08 35.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX90471.1 - 7.8e-09 35.5 0.0 8.5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAX90471.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family SRP9-21 PF05486.12 EAX90472.1 - 0.18 12.2 8.7 2.3 8.7 0.0 3.0 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF1935 PF09149.10 EAX90472.1 - 0.19 12.1 4.2 0.35 11.3 3.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1935) PS-DH PF14765.6 EAX90472.1 - 0.47 9.6 5.2 0.89 8.7 5.2 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase DUF3332 PF11810.8 EAX90472.1 - 1.3 8.6 5.7 3 7.4 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) MlaD PF02470.20 EAX90472.1 - 1.6 9.0 5.1 80 3.6 4.8 2.8 1 1 1 2 2 2 0 MlaD protein GAGA_bind PF06217.12 EAX90472.1 - 3 8.0 6.4 14 5.8 0.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family FSAP_sig_propep PF03032.15 EAX90472.1 - 4.2 7.5 6.8 12 6.1 6.8 1.8 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide FAM219A PF15260.6 EAX90472.1 - 9.3 6.6 9.5 11 6.4 1.1 3.1 3 1 1 4 4 4 0 Protein family FAM219A T5orf172 PF10544.9 EAX90473.1 - 0.00058 20.4 0.1 0.0012 19.4 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX90473.1 - 0.0055 16.3 0.7 0.11 12.0 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX90473.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX90474.1 - 5.6e-156 517.1 13.6 7.1e-156 516.8 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90474.1 - 0.057 13.9 1.6 0.33 11.4 0.2 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX90474.1 - 0.14 12.0 1.5 0.29 11.0 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX90474.1 - 0.29 11.6 6.2 2.1 8.9 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX90474.1 - 0.91 9.9 5.0 9.6 6.6 0.1 3.7 4 1 0 4 4 4 0 Tup N-terminal TMP PF05017.14 EAX90476.1 - 0.072 13.7 4.9 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90477.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Mac-1 PF09028.10 EAX90478.1 - 4.9e-10 39.0 1.7 5.8e-10 38.8 1.7 1.0 1 0 0 1 1 1 1 Mac 1 FliH PF02108.16 EAX90478.1 - 0.24 11.5 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH LAP1C PF05609.12 EAX90479.1 - 0.0025 17.0 29.4 0.0031 16.7 29.4 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) RIFIN PF02009.16 EAX90479.1 - 0.011 15.6 18.4 0.011 15.6 18.4 2.1 1 1 1 2 2 2 0 Rifin Mitofilin PF09731.9 EAX90479.1 - 0.063 12.1 43.5 0.093 11.6 43.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Rax2 PF12768.7 EAX90479.1 - 0.081 12.4 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Dapper PF15268.6 EAX90479.1 - 0.09 11.6 28.9 0.1 11.5 28.9 1.1 1 0 0 1 1 1 0 Dapper DUF966 PF06136.13 EAX90479.1 - 0.68 9.6 29.7 0.91 9.2 29.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.7 EAX90479.1 - 0.72 7.9 32.0 0.84 7.7 32.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 EAX90479.1 - 5.5 7.0 60.0 9.3 6.2 60.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.16 EAX90479.1 - 6.1 5.6 16.9 7 5.4 16.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UCH PF00443.29 EAX90480.1 - 4e-40 137.9 1.1 4e-40 137.9 1.1 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX90480.1 - 2.5e-06 27.3 5.5 0.0001 22.0 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Trp_repressor PF01371.19 EAX90480.1 - 3.8 7.7 5.5 17 5.6 0.1 4.6 5 0 0 5 5 5 0 Trp repressor protein Peptidase_M8 PF01457.16 EAX90481.1 - 6.1e-28 97.8 0.1 5.3e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Leishmanolysin Mid2 PF04478.12 EAX90481.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX90481.1 - 0.021 14.9 3.8 0.054 13.6 3.8 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TaqI_C PF12950.7 EAX90481.1 - 0.095 12.8 1.5 0.22 11.6 1.5 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain DUF1180 PF06679.12 EAX90481.1 - 1.1 9.7 6.0 3.1 8.2 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DDE_Tnp_4 PF13359.6 EAX90483.1 - 1.4e-20 73.5 0.0 4.4e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease UCH PF00443.29 EAX90483.1 - 5.3e-08 32.7 0.1 2.1e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX90483.1 - 0.0035 17.0 0.1 0.043 13.4 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1_2 PF13586.6 EAX90483.1 - 0.15 12.5 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX90484.1 - 5.7e-05 22.8 1.3 0.0053 16.4 0.6 2.3 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease PTR PF12789.7 EAX90488.1 - 2e-30 104.6 10.7 2e-30 104.6 10.7 4.9 4 1 1 5 5 5 1 Phage tail repeat like YmaF PF12788.7 EAX90488.1 - 0.097 13.2 12.2 3 8.4 3.3 3.5 2 1 0 2 2 2 0 YmaF family DUF1493 PF07377.12 EAX90489.1 - 0.089 13.3 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX90490.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90491.1 - 0.072 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP IBD PF10416.9 EAX90492.1 - 6.9e-37 126.3 1.3 8e-37 126.1 1.3 1.0 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD ToxN_toxin PF13958.6 EAX90492.1 - 0.056 13.7 0.0 0.075 13.3 0.0 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system IBD PF10416.9 EAX90493.1 - 2e-44 150.7 3.2 2.8e-44 150.2 3.2 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Cullin PF00888.22 EAX90494.1 - 5.8e-16 58.2 15.4 5.8e-16 58.2 15.4 2.4 1 1 1 2 2 2 1 Cullin family DUF1027 PF06265.11 EAX90494.1 - 0.016 15.2 0.7 0.089 12.8 0.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Cullin_Nedd8 PF10557.9 EAX90494.1 - 0.034 14.2 0.1 0.034 14.2 0.1 3.9 4 0 0 4 4 4 0 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EAX90494.1 - 0.14 12.7 1.6 4.1 8.0 0.1 3.5 3 1 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF2779 PF11074.8 EAX90494.1 - 0.49 10.9 13.3 1.9 9.0 1.0 4.0 3 1 0 3 3 3 0 Domain of unknown function(DUF2779) Glyco_hydro_77 PF02446.17 EAX90495.1 - 1.2e-26 93.6 0.0 5.3e-26 91.5 0.0 1.9 1 1 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAX90495.1 - 1.7e-23 82.3 0.0 4.5e-11 42.5 0.0 3.4 3 0 0 3 3 3 2 Starch binding domain Taxilin PF09728.9 EAX90496.1 - 1.7e-05 24.1 13.6 2.3e-05 23.8 13.6 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TSC22 PF01166.18 EAX90496.1 - 1.8e-05 25.0 6.5 0.0012 19.1 0.9 2.7 2 0 0 2 2 2 1 TSC-22/dip/bun family Fez1 PF06818.15 EAX90496.1 - 0.00077 20.0 6.8 0.0012 19.3 6.8 1.3 1 0 0 1 1 1 1 Fez1 WXG100 PF06013.12 EAX90496.1 - 0.001 19.2 3.0 0.037 14.2 0.5 2.3 1 1 1 2 2 2 1 Proteins of 100 residues with WXG DUF5082 PF16888.5 EAX90496.1 - 0.0012 19.1 13.1 0.0096 16.2 12.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) GIT_CC PF16559.5 EAX90496.1 - 0.0023 17.7 1.6 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 EAX90496.1 - 0.0027 17.1 11.2 0.0065 15.8 11.1 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EAX90496.1 - 0.0031 17.4 9.6 0.046 13.6 3.1 2.6 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH TACC_C PF05010.14 EAX90496.1 - 0.0032 17.3 10.1 0.37 10.5 2.8 2.2 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PRKG1_interact PF15898.5 EAX90496.1 - 0.0038 18.1 7.8 0.017 16.0 7.2 2.1 1 1 1 2 2 2 1 cGMP-dependent protein kinase interacting domain MIT PF04212.18 EAX90496.1 - 0.0038 17.3 14.7 0.32 11.1 1.3 3.5 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain Golgin_A5 PF09787.9 EAX90496.1 - 0.004 16.7 6.2 0.0052 16.3 6.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 SNAP PF14938.6 EAX90496.1 - 0.0048 16.4 10.8 0.011 15.2 10.8 1.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MLP1_2 PF07926.12 EAX90496.1 - 0.0068 16.5 13.8 0.093 12.8 3.2 2.2 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein HpaB_N PF11794.8 EAX90496.1 - 0.0069 16.1 0.8 0.0086 15.8 0.8 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal BicD PF09730.9 EAX90496.1 - 0.0081 14.6 8.5 0.012 14.1 8.5 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D ADIP PF11559.8 EAX90496.1 - 0.0092 16.1 10.0 0.052 13.6 3.1 2.2 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 EAX90496.1 - 0.011 15.8 6.4 2.2 8.5 0.7 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Prefoldin PF02996.17 EAX90496.1 - 0.012 15.5 12.6 0.48 10.3 1.2 3.8 2 1 2 4 4 4 0 Prefoldin subunit K-box PF01486.17 EAX90496.1 - 0.012 15.7 2.3 1.5 9.0 0.2 2.4 2 0 0 2 2 2 0 K-box region BST2 PF16716.5 EAX90496.1 - 0.014 16.0 6.9 0.15 12.7 1.1 2.4 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 EAX90496.1 - 0.014 15.6 6.6 0.097 12.9 6.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 EAX90496.1 - 0.014 15.4 10.8 0.04 14.0 2.4 3.0 2 2 1 3 3 3 0 bZIP transcription factor SHNi-TPR PF10516.9 EAX90496.1 - 0.015 14.7 1.9 0.37 10.3 0.1 3.6 2 1 1 3 3 3 0 SHNi-TPR DivIC PF04977.15 EAX90496.1 - 0.015 15.0 7.7 0.78 9.6 1.8 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EAX90496.1 - 0.016 15.8 0.8 1.8 9.2 0.1 2.4 2 0 0 2 2 2 0 SlyX Filament PF00038.21 EAX90496.1 - 0.02 14.5 10.3 0.085 12.4 3.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 EAX90496.1 - 0.02 15.4 13.7 0.37 11.3 2.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_12 PF13424.6 EAX90496.1 - 0.021 15.1 2.8 0.47 10.8 2.4 2.9 2 1 0 2 2 1 0 Tetratricopeptide repeat T3SSipB PF16535.5 EAX90496.1 - 0.024 15.1 7.7 0.083 13.4 7.2 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4201 PF13870.6 EAX90496.1 - 0.026 14.3 9.0 0.052 13.3 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Leu_zip PF15294.6 EAX90496.1 - 0.027 14.0 10.0 0.21 11.1 0.5 2.2 1 1 1 2 2 2 0 Leucine zipper YscO PF07321.12 EAX90496.1 - 0.032 14.2 5.1 0.036 14.0 1.1 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO DUF641 PF04859.12 EAX90496.1 - 0.034 14.5 9.7 0.45 10.8 2.1 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 EAX90496.1 - 0.034 14.2 7.0 0.057 13.5 7.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EAX90496.1 - 0.036 14.5 10.1 1.3 9.5 2.1 2.5 1 1 0 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 EAX90496.1 - 0.037 14.2 10.7 0.055 13.7 9.1 2.1 1 1 1 2 2 1 0 Fibrinogen alpha/beta chain family SAP30_Sin3_bdg PF13867.6 EAX90496.1 - 0.039 14.3 0.4 8 6.9 0.1 2.9 2 2 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 HBM PF16591.5 EAX90496.1 - 0.04 13.3 6.6 0.29 10.5 0.5 2.2 1 1 1 2 2 2 0 Helical bimodular sensor domain HAP1_N PF04849.13 EAX90496.1 - 0.04 13.1 7.3 0.28 10.4 6.8 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region MCC-bdg_PDZ PF10506.9 EAX90496.1 - 0.043 13.8 5.9 0.2 11.7 0.4 3.2 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Pox_A_type_inc PF04508.12 EAX90496.1 - 0.048 13.5 0.8 0.048 13.5 0.8 3.0 2 1 1 3 3 2 0 Viral A-type inclusion protein repeat MscS_porin PF12795.7 EAX90496.1 - 0.05 13.1 10.1 3.6 7.1 1.5 2.2 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 EAX90496.1 - 0.062 12.9 3.6 0.068 12.7 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAX90496.1 - 0.063 12.1 10.6 0.14 11.0 4.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EAX90496.1 - 0.067 13.4 9.5 0.81 9.9 3.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.15 EAX90496.1 - 0.07 13.2 5.7 2.1 8.5 0.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.8 EAX90496.1 - 0.073 12.4 8.6 0.057 12.7 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EAX90496.1 - 0.077 13.2 8.9 0.39 10.9 8.9 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CP12 PF02672.15 EAX90496.1 - 0.09 13.5 5.2 0.45 11.3 0.2 2.8 1 1 2 3 3 3 0 CP12 domain Use1 PF09753.9 EAX90496.1 - 0.098 12.4 9.1 0.14 11.9 9.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF349 PF03993.12 EAX90496.1 - 0.11 12.8 6.9 0.57 10.5 1.4 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) FTHFS PF01268.19 EAX90496.1 - 0.12 10.6 1.3 0.13 10.4 1.3 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase TPR_10 PF13374.6 EAX90496.1 - 0.12 12.2 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CorA PF01544.18 EAX90496.1 - 0.13 11.6 1.3 0.16 11.3 1.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_HK97_TLTM PF06120.11 EAX90496.1 - 0.14 11.3 9.2 0.18 10.9 9.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein FlaC_arch PF05377.11 EAX90496.1 - 0.14 12.6 3.6 2.7 8.5 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 EAX90496.1 - 0.15 12.0 8.2 0.3 11.1 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 EAX90496.1 - 0.16 11.2 8.3 0.21 10.8 7.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 EAX90496.1 - 0.17 12.0 11.2 0.32 11.1 11.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sec5 PF15469.6 EAX90496.1 - 0.17 11.7 12.0 11 5.8 0.0 3.2 1 1 1 2 2 2 0 Exocyst complex component Sec5 ING PF12998.7 EAX90496.1 - 0.19 12.3 5.6 0.24 12.0 4.5 1.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Atg14 PF10186.9 EAX90496.1 - 0.2 10.7 10.9 2.1 7.4 10.2 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGAP_C PF03836.15 EAX90496.1 - 0.22 11.7 12.5 0.96 9.6 12.1 2.2 1 1 0 1 1 1 0 RasGAP C-terminus TPR_7 PF13176.6 EAX90496.1 - 0.23 11.6 2.9 3.4 7.9 0.4 3.5 3 1 0 3 3 2 0 Tetratricopeptide repeat CC2-LZ PF16516.5 EAX90496.1 - 0.28 11.6 8.3 0.63 10.4 8.1 1.7 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4326 PF14216.6 EAX90496.1 - 0.35 11.6 3.2 12 6.7 1.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) Herpes_BLRF2 PF05812.12 EAX90496.1 - 0.37 10.9 5.2 4.7 7.4 0.7 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein YabA PF06156.13 EAX90496.1 - 0.38 11.4 7.2 1.4 9.6 2.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EAX90496.1 - 0.41 10.5 10.7 20 4.9 10.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.12 EAX90496.1 - 0.63 10.5 10.0 1.1 9.7 4.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Turandot PF07240.11 EAX90496.1 - 0.79 9.7 5.0 12 5.9 0.0 3.0 1 1 1 3 3 3 0 Stress-inducible humoral factor Turandot HAUS6_N PF14661.6 EAX90496.1 - 0.81 9.2 8.3 3.2 7.3 4.0 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TPR_11 PF13414.6 EAX90496.1 - 0.82 9.4 12.3 0.49 10.1 0.8 4.4 2 1 3 5 5 4 0 TPR repeat TPR_1 PF00515.28 EAX90496.1 - 0.88 9.5 7.1 2.5 8.1 0.2 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX90496.1 - 0.91 9.8 5.9 1.8 8.9 0.4 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 EAX90496.1 - 1.3 9.3 9.7 34 4.7 9.7 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 EAX90496.1 - 1.6 8.3 9.3 5.3 6.6 9.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4200 PF13863.6 EAX90496.1 - 1.6 9.1 18.7 0.34 11.3 4.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) KELK PF15796.5 EAX90496.1 - 2.2 8.8 9.4 1.4 9.4 2.9 2.8 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4337 PF14235.6 EAX90496.1 - 2.7 8.1 12.1 0.68 10.0 6.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FapA PF03961.13 EAX90496.1 - 2.8 6.4 11.9 4.3 5.8 1.2 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A CREPT PF16566.5 EAX90496.1 - 3.2 7.9 8.8 3.7 7.7 2.7 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Csm1_N PF18504.1 EAX90496.1 - 4.2 7.8 11.9 5.7 7.3 1.7 3.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Rad50_zn_hook PF04423.14 EAX90496.1 - 6.5 6.7 11.0 1.9 8.4 0.3 4.1 4 0 0 4 4 3 0 Rad50 zinc hook motif LRR_6 PF13516.6 EAX90497.1 - 3.7e-06 26.6 22.0 0.00052 19.9 0.3 8.5 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 EAX90497.1 - 0.048 14.1 58.6 0.049 14.1 3.7 8.7 4 2 4 9 9 9 0 Leucine Rich repeats (2 copies) IspD PF01128.19 EAX90497.1 - 0.14 11.9 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LRR_1 PF00560.33 EAX90497.1 - 1 10.2 31.4 1.5 9.7 0.2 9.3 9 1 0 9 9 9 0 Leucine Rich Repeat LCAT PF02450.15 EAX90498.1 - 2.5e-30 105.9 0.2 3.7e-28 98.8 0.0 2.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAX90498.1 - 0.0016 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX90498.1 - 0.0056 17.3 0.0 0.0076 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EAX90498.1 - 0.0073 15.9 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 EAX90498.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 EAX90498.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF676 PF05057.14 EAX90498.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 EAX90498.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 EAX90498.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF2492 PF10678.9 EAX90498.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) Lipase_3 PF01764.25 EAX90498.1 - 0.053 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 EAX90498.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) KAP PF05804.12 EAX90499.1 - 1.6e-28 99.3 19.7 6.7e-26 90.7 19.7 2.2 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) WAPL PF07814.13 EAX90499.1 - 0.029 13.1 4.6 0.17 10.6 0.5 2.6 2 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin UNC45-central PF11701.8 EAX90499.1 - 0.088 12.8 1.2 0.47 10.4 0.3 2.7 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central RICTOR_M PF14666.6 EAX90499.1 - 1.5 8.6 6.2 0.78 9.5 0.2 3.8 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, middle domain DUF3447 PF11929.8 EAX90500.1 - 4.7e-37 125.8 4.5 4.7e-37 125.8 4.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90500.1 - 0.0045 17.5 0.0 0.04 14.5 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX90501.1 - 3.5e-40 136.5 32.3 4e-13 49.7 1.8 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX90501.1 - 5e-31 106.5 5.2 5e-31 106.5 5.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX90501.1 - 3e-30 104.2 8.5 4.9e-07 30.2 0.0 7.1 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX90501.1 - 6.2e-30 102.3 10.6 1.8e-05 25.0 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAX90501.1 - 7.7e-27 90.4 7.6 3.7e-05 23.8 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX90501.1 - 8.2e-26 89.7 5.9 5.2e-08 33.0 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) HEM4 PF02602.15 EAX90501.1 - 0.096 12.0 0.1 1.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD LRR_4 PF12799.7 EAX90502.1 - 1.8e-06 28.2 6.3 0.00026 21.3 0.4 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX90502.1 - 0.005 16.6 2.0 0.013 15.3 1.2 2.1 2 1 0 2 2 2 1 Leucine rich repeat EF-hand_1 PF00036.32 EAX90504.1 - 2.9e-36 120.3 11.1 6.4e-10 37.9 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX90504.1 - 4.3e-31 107.2 7.5 3.7e-15 56.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAX90504.1 - 1.2e-27 95.5 11.7 3.7e-11 42.7 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EAX90504.1 - 2.7e-27 92.3 6.6 4.9e-09 35.4 0.1 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EAX90504.1 - 1.1e-13 50.0 14.2 6.8e-06 25.3 0.2 4.7 4 2 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX90504.1 - 5.7e-11 42.6 0.2 8.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAX90504.1 - 4.1e-08 33.1 4.0 0.00013 21.9 0.4 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAX90504.1 - 9e-05 22.8 0.1 0.12 12.7 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 EAX90504.1 - 0.0017 17.0 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_3 PF13624.6 EAX90504.1 - 0.0042 16.9 0.6 0.16 11.7 0.2 2.1 2 0 0 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EAX90504.1 - 0.0059 16.9 1.0 2.4 8.6 0.2 2.9 1 1 1 3 3 3 1 EF-hand domain SUB1_ProdP9 PF18213.1 EAX90504.1 - 0.0059 16.4 0.5 0.03 14.2 0.1 2.0 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 EAX90504.1 - 0.014 16.2 0.3 5.6 7.9 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Phage_TAC_12 PF12363.8 EAX90504.1 - 0.018 15.5 1.3 1.2 9.5 0.3 2.5 1 1 2 3 3 3 0 Phage tail assembly chaperone protein, TAC SurA_N_2 PF13623.6 EAX90504.1 - 0.019 14.8 0.9 1.1 9.1 0.1 2.6 1 1 2 3 3 3 0 SurA N-terminal domain HTH_40 PF14493.6 EAX90504.1 - 0.026 15.0 0.8 7 7.2 0.1 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain US30 PF17624.2 EAX90504.1 - 0.028 13.5 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function Staphylokinase PF02821.16 EAX90504.1 - 0.033 14.6 0.8 1.7 9.1 0.1 2.6 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family DUF4601 PF15373.6 EAX90504.1 - 0.036 13.0 0.1 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) Sigma54_CBD PF04963.13 EAX90504.1 - 0.052 13.4 0.1 0.069 13.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain UPF0154 PF03672.13 EAX90504.1 - 0.054 13.5 0.2 3.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) MgtE_N PF03448.17 EAX90504.1 - 0.13 12.9 2.8 0.62 10.7 0.5 2.6 2 1 1 3 3 3 0 MgtE intracellular N domain TerB PF05099.13 EAX90504.1 - 0.15 12.0 2.8 7.6 6.5 0.1 2.8 1 1 0 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.13 EAX90504.1 - 0.17 11.8 0.8 27 4.6 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 EAX90504.1 - 0.23 11.7 1.2 8.5 6.7 0.0 2.6 1 1 2 3 3 3 0 Dockerin type I domain Gp-FAR-1 PF05823.12 EAX90504.1 - 0.28 11.5 2.3 1.7 9.0 0.1 2.5 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glycos_trans_3N PF02885.17 EAX90504.1 - 0.57 10.1 5.0 19 5.2 0.1 3.8 2 2 1 3 3 3 0 Glycosyl transferase family, helical bundle domain EF-hand_1 PF00036.32 EAX90505.1 - 2.9e-36 120.3 11.1 6.4e-10 37.9 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX90505.1 - 4.3e-31 107.2 7.5 3.7e-15 56.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAX90505.1 - 1.2e-27 95.5 11.7 3.7e-11 42.7 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EAX90505.1 - 2.7e-27 92.3 6.6 4.9e-09 35.4 0.1 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EAX90505.1 - 1.1e-13 50.0 14.2 6.8e-06 25.3 0.2 4.7 4 2 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX90505.1 - 5.7e-11 42.6 0.2 8.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAX90505.1 - 4.1e-08 33.1 4.0 0.00013 21.9 0.4 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAX90505.1 - 9e-05 22.8 0.1 0.12 12.7 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 EAX90505.1 - 0.0017 17.0 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_3 PF13624.6 EAX90505.1 - 0.0042 16.9 0.6 0.16 11.7 0.2 2.1 2 0 0 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EAX90505.1 - 0.0059 16.9 1.0 2.4 8.6 0.2 2.9 1 1 1 3 3 3 1 EF-hand domain SUB1_ProdP9 PF18213.1 EAX90505.1 - 0.0059 16.4 0.5 0.03 14.2 0.1 2.0 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 EAX90505.1 - 0.014 16.2 0.3 5.6 7.9 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Phage_TAC_12 PF12363.8 EAX90505.1 - 0.018 15.5 1.3 1.2 9.5 0.3 2.5 1 1 2 3 3 3 0 Phage tail assembly chaperone protein, TAC SurA_N_2 PF13623.6 EAX90505.1 - 0.019 14.8 0.9 1.1 9.1 0.1 2.6 1 1 2 3 3 3 0 SurA N-terminal domain HTH_40 PF14493.6 EAX90505.1 - 0.026 15.0 0.8 7 7.2 0.1 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain US30 PF17624.2 EAX90505.1 - 0.028 13.5 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function Staphylokinase PF02821.16 EAX90505.1 - 0.033 14.6 0.8 1.7 9.1 0.1 2.6 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family DUF4601 PF15373.6 EAX90505.1 - 0.036 13.0 0.1 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) Sigma54_CBD PF04963.13 EAX90505.1 - 0.052 13.4 0.1 0.069 13.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain UPF0154 PF03672.13 EAX90505.1 - 0.054 13.5 0.2 3.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) MgtE_N PF03448.17 EAX90505.1 - 0.13 12.9 2.8 0.62 10.7 0.5 2.6 2 1 1 3 3 3 0 MgtE intracellular N domain TerB PF05099.13 EAX90505.1 - 0.15 12.0 2.8 7.6 6.5 0.1 2.8 1 1 0 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.13 EAX90505.1 - 0.17 11.8 0.8 27 4.6 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 EAX90505.1 - 0.23 11.7 1.2 8.5 6.7 0.0 2.6 1 1 2 3 3 3 0 Dockerin type I domain Gp-FAR-1 PF05823.12 EAX90505.1 - 0.28 11.5 2.3 1.7 9.0 0.1 2.5 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glycos_trans_3N PF02885.17 EAX90505.1 - 0.57 10.1 5.0 19 5.2 0.1 3.8 2 2 1 3 3 3 0 Glycosyl transferase family, helical bundle domain Arm_3 PF16186.5 EAX90506.1 - 1.1e-05 24.9 0.9 3.3e-05 23.4 0.9 1.8 1 0 0 1 1 1 1 Atypical Arm repeat Bromodomain PF00439.25 EAX90507.1 - 3.4e-22 78.3 0.3 2.5e-21 75.5 0.1 2.2 2 1 0 2 2 2 1 Bromodomain Lin0512_fam PF09585.10 EAX90508.1 - 0.05 13.6 0.0 0.06 13.4 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) BACK PF07707.15 EAX90509.1 - 0.0029 17.7 5.9 0.17 12.0 0.0 3.9 3 1 1 4 4 4 2 BTB And C-terminal Kelch Peptidase_S46 PF10459.9 EAX90509.1 - 1.1 7.9 22.5 1.4 7.4 22.5 1.1 1 0 0 1 1 1 0 Peptidase S46 ApoO PF09769.9 EAX90509.1 - 2.8 7.9 4.5 1 9.4 0.8 2.1 2 0 0 2 2 2 0 Apolipoprotein O PSP PF04046.16 EAX90510.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX90511.1 - 0.085 13.3 0.4 0.18 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4738 PF15889.5 EAX90512.1 - 0.06 13.2 1.2 0.15 11.9 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4738) DUF4116 PF13475.6 EAX90512.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX90514.1 - 3.6e-158 524.3 13.4 4.8e-158 523.9 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX90514.1 - 0.99 9.8 5.9 12 6.3 0.0 3.8 4 0 0 4 4 4 0 Tup N-terminal FKBP_N PF01346.18 EAX90514.1 - 1.3 10.0 4.5 0.78 10.7 0.9 2.3 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX90514.1 - 3.4 8.2 8.3 1.7 9.1 0.7 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX90515.1 - 1.8e-07 31.6 0.3 3.8e-07 30.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX90515.1 - 0.13 12.9 0.3 0.35 11.6 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 SHE3 PF17078.5 EAX90516.1 - 0.022 14.5 2.7 0.025 14.3 2.7 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spo12 PF05032.12 EAX90516.1 - 0.53 10.2 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family YkyA PF10368.9 EAX90518.1 - 0.027 14.1 9.0 0.083 12.6 9.0 1.9 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein V-ATPase_G_2 PF16999.5 EAX90518.1 - 0.042 14.3 3.7 0.11 12.9 3.7 1.8 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit FliS PF02561.14 EAX90518.1 - 0.042 14.1 1.3 0.11 12.8 0.7 2.0 1 1 0 1 1 1 0 Flagellar protein FliS TraF_2 PF13729.6 EAX90518.1 - 0.089 12.1 1.2 0.15 11.4 1.2 1.5 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Apolipoprotein PF01442.18 EAX90518.1 - 0.72 9.7 9.3 3.6 7.4 2.0 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain MutS_IV PF05190.18 EAX90518.1 - 1.6 9.1 9.4 6.6 7.1 0.8 4.0 3 1 1 4 4 4 0 MutS family domain IV Fib_alpha PF08702.10 EAX90518.1 - 2 8.6 16.8 0.24 11.6 4.7 3.1 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3837 PF12939.7 EAX90518.1 - 2.5 8.5 5.6 5.9 7.4 1.9 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) PhoU PF01895.19 EAX90518.1 - 3.6 8.1 12.7 1.7 9.1 4.9 3.3 1 1 1 2 2 2 0 PhoU domain TnpV PF14198.6 EAX90518.1 - 3.9 7.5 9.0 7.3 6.6 0.6 2.6 1 1 1 2 2 2 0 Transposon-encoded protein TnpV Phasin PF05597.11 EAX90518.1 - 5.2 7.1 11.3 23 5.0 3.5 2.9 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 EAX90518.1 - 6.9 5.9 8.3 10 5.4 7.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CdvA PF18822.1 EAX90518.1 - 9.4 6.1 14.5 0.74 9.7 2.9 3.4 4 0 0 4 4 4 0 CdvA-like coiled-coil domain Ank_2 PF12796.7 EAX90519.1 - 1.7e-19 70.1 2.6 6e-05 23.6 0.3 5.0 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90519.1 - 1.9e-17 61.5 3.7 0.23 12.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAX90519.1 - 1.7e-16 60.3 0.4 0.00019 21.9 0.1 7.0 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90519.1 - 9.7e-14 51.3 0.6 0.63 10.4 0.0 6.7 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX90519.1 - 5.5e-08 32.9 1.1 0.41 11.2 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Bromodomain PF00439.25 EAX90520.1 - 9.7e-05 22.4 0.3 0.00055 20.0 0.0 2.1 2 1 0 2 2 2 1 Bromodomain DDRGK PF09756.9 EAX90520.1 - 0.024 14.2 0.8 0.032 13.8 0.8 1.1 1 0 0 1 1 1 0 DDRGK domain Synaptobrevin PF00957.21 EAX90521.1 - 4e-22 77.8 0.1 6e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin TSKS PF15358.6 EAX90521.1 - 0.019 13.3 0.4 0.024 13.0 0.4 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate COG6 PF06419.11 EAX90521.1 - 0.03 12.6 0.3 0.037 12.3 0.3 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 GP41 PF00517.17 EAX90521.1 - 0.064 13.1 1.1 0.1 12.5 0.7 1.5 1 1 0 1 1 1 0 Retroviral envelope protein tRNA-synt_2 PF00152.20 EAX90521.1 - 0.17 11.0 0.3 0.23 10.5 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) SANT_DAMP1_like PF16282.5 EAX90521.1 - 0.26 11.5 2.2 1.1 9.5 1.2 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Transpos_assoc PF13963.6 EAX90522.1 - 0.047 14.0 0.3 0.077 13.3 0.3 1.3 1 0 0 1 1 1 0 Transposase-associated domain TRAP_alpha PF03896.16 EAX90522.1 - 0.84 8.8 2.9 1.2 8.3 2.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF5082 PF16888.5 EAX90523.1 - 0.0059 16.9 3.7 0.011 16.0 3.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Meth_synt_2 PF01717.18 EAX90523.1 - 0.056 12.7 0.2 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain RICH PF05062.12 EAX90523.1 - 1.1 9.7 7.9 1.5 9.2 4.7 2.3 1 1 1 2 2 2 0 RICH domain P16-Arc PF04699.14 EAX90524.1 - 0.012 16.1 4.0 0.015 15.8 3.1 1.6 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TMPIT PF07851.13 EAX90524.1 - 0.19 10.9 13.0 0.065 12.5 9.4 1.8 2 0 0 2 2 2 0 TMPIT-like protein DUF853 PF05872.12 EAX90524.1 - 0.48 8.9 6.3 0.68 8.4 6.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ZIP4_domain PF18292.1 EAX90524.1 - 0.53 10.2 5.3 0.17 11.8 1.6 2.0 2 1 0 2 2 2 0 Zinc transporter ZIP4 domain COMM_domain PF07258.14 EAX90527.1 - 1.2e-11 44.6 1.2 4e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 COMM domain IL17_R_N PF15037.6 EAX90527.1 - 0.034 13.1 0.1 0.047 12.6 0.1 1.2 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region XRN1_DBM PF18245.1 EAX90528.1 - 0.035 14.0 3.3 0.078 13.0 3.3 1.5 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif Cyclin_N PF00134.23 EAX90529.1 - 2.9e-19 69.1 0.1 4.8e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4407 PF14362.6 EAX90530.1 - 1.7 7.9 4.5 2.5 7.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FERM_M PF00373.18 EAX90532.1 - 6.1e-11 42.8 0.0 0.00037 20.9 0.2 3.5 3 0 0 3 3 3 2 FERM central domain IRS PF02174.17 EAX90532.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Glutaredoxin2_C PF04399.13 EAX90532.1 - 0.18 11.6 1.2 1.1 9.1 0.2 2.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain RecG_N PF17190.4 EAX90532.1 - 0.56 11.0 0.0 0.56 11.0 0.0 4.8 6 0 0 6 6 6 0 RecG N-terminal helical domain LRR_5 PF13306.6 EAX90534.1 - 2e-05 24.5 10.1 0.00018 21.4 0.2 2.6 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) CPSase_sm_chain PF00988.22 EAX90534.1 - 0.019 14.8 0.2 0.025 14.4 0.2 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain PSP PF04046.16 EAX90535.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90536.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX90540.1 - 6.4e-157 520.2 13.5 7.6e-157 520.0 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX90540.1 - 0.43 11.1 7.3 2 9.0 0.8 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX90540.1 - 0.52 10.6 3.5 1.1 9.6 0.1 3.0 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX90540.1 - 1.6 9.3 6.1 0.79 10.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DapH_N PF08503.10 EAX90542.1 - 0.015 15.5 0.4 0.1 12.9 0.1 2.3 1 1 1 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Chlam_OMP6 PF03504.13 EAX90542.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Ank_2 PF12796.7 EAX90544.1 - 1.4e-21 76.8 2.0 1.6e-09 38.2 0.0 5.0 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90544.1 - 3.5e-14 53.0 1.3 0.0024 18.4 0.0 5.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90544.1 - 2.7e-13 48.8 5.0 0.056 14.0 0.1 8.1 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 EAX90544.1 - 4.3e-13 49.2 3.8 0.0015 18.8 0.0 6.2 2 2 5 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX90544.1 - 8.7e-11 41.8 3.0 0.012 16.0 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX90544.1 - 0.00013 21.8 8.0 0.075 13.0 3.2 3.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) FH2 PF02181.23 EAX90545.1 - 1.9e-45 155.6 6.1 1.9e-45 155.6 6.1 16.1 2 2 11 15 15 15 1 Formin Homology 2 Domain Beach PF02138.18 EAX90547.1 - 2.4e-90 302.7 0.4 5.4e-90 301.5 0.4 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Prok-RING_1 PF14446.6 EAX90547.1 - 5.5 7.0 10.6 13 5.8 10.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 UBA_4 PF14555.6 EAX90548.1 - 0.0021 17.9 0.1 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain tRNA_NucTransf2 PF09249.11 EAX90548.1 - 0.11 12.7 0.7 1.9 8.8 0.3 2.5 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain GLE1 PF07817.13 EAX90548.1 - 0.11 11.7 3.5 0.25 10.5 3.5 1.6 1 0 0 1 1 1 0 GLE1-like protein T_Ag_DNA_bind PF02217.16 EAX90548.1 - 7.6 7.2 7.2 61 4.3 0.5 4.1 3 1 1 4 4 4 0 Origin of replication binding protein DUF3839 PF12943.7 EAX90549.1 - 3.5e-123 409.7 8.7 4.1e-123 409.5 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX90549.1 - 0.042 14.1 1.6 0.3 11.4 0.0 2.6 2 1 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX90549.1 - 0.083 13.4 3.0 1.8 9.1 1.8 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LD_cluster2 PF18163.1 EAX90549.1 - 0.17 11.4 0.1 0.76 9.3 0.1 2.0 1 1 0 1 1 1 0 SLOG cluster2 DUF1493 PF07377.12 EAX90550.1 - 0.074 13.5 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX90551.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90552.1 - 0.075 12.9 0.9 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90553.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90554.1 - 0.075 12.9 0.9 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 PSP DUF2294 PF10057.9 EAX90555.1 - 0.019 15.1 0.3 0.18 11.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Ank_2 PF12796.7 EAX90556.1 - 9.4e-17 61.4 0.5 4.6e-13 49.6 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90556.1 - 1.7e-11 43.2 1.2 0.05 14.2 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX90556.1 - 7.6e-11 42.0 0.8 9.5e-08 32.2 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX90556.1 - 9.7e-11 42.0 0.6 7.1e-05 23.3 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX90556.1 - 0.00059 20.2 0.0 0.68 10.5 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Nop52 PF05997.12 EAX90557.1 - 4.9e-29 101.7 5.2 4.9e-29 101.7 5.2 1.4 2 0 0 2 2 2 1 Nucleolar protein,Nop52 DUF1419 PF07215.11 EAX90557.1 - 0.061 13.4 0.2 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) Pkinase PF00069.25 EAX90558.1 - 6.8e-28 97.8 0.1 8.4e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90558.1 - 4.9e-16 58.8 0.0 5.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX90558.1 - 1.9e-09 36.8 0.1 2.5e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX90558.1 - 0.005 16.2 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX90558.1 - 0.009 16.0 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX90558.1 - 0.012 15.2 0.3 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EAX90558.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Kinase-like DUF4028 PF13220.6 EAX90558.1 - 0.18 11.6 1.2 3 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4028) Y_phosphatase2 PF03162.13 EAX90559.1 - 2.8e-59 199.4 0.0 3.3e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EAX90559.1 - 1.2e-06 28.6 0.0 1.4e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EAX90559.1 - 0.00012 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAX90559.1 - 0.0044 16.6 0.1 0.0083 15.7 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CENP-X PF09415.10 EAX90560.1 - 2.4e-15 56.6 0.3 3.1e-15 56.2 0.3 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Ras PF00071.22 EAX90561.1 - 2.2e-55 186.7 0.1 2.5e-55 186.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90561.1 - 7.1e-20 71.4 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90561.1 - 5.8e-12 45.4 0.0 7.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX90561.1 - 4e-07 29.8 0.0 7.4e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX90561.1 - 0.0027 17.8 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EAX90561.1 - 0.13 12.5 0.8 7.2 6.8 0.1 2.5 2 2 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EAX90561.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PSP PF04046.16 EAX90562.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90563.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90564.1 - 0.097 13.1 0.6 0.2 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX90566.1 - 8.9e-147 487.0 13.5 1e-146 486.8 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX90566.1 - 0.066 13.1 0.6 0.16 11.8 0.6 1.7 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX90566.1 - 0.091 13.0 4.1 0.2 12.0 0.1 2.9 2 1 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX90566.1 - 0.73 10.3 7.0 2.7 8.5 2.0 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMWPc PF01451.21 EAX90567.1 - 3.8e-33 114.9 0.0 4.3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ank_2 PF12796.7 EAX90568.1 - 1.5e-57 192.1 32.6 3.5e-13 50.0 0.4 6.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90568.1 - 2.7e-49 164.6 10.3 6.6e-09 35.9 0.1 7.8 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX90568.1 - 1.1e-44 150.2 17.5 8.4e-10 39.0 0.2 9.9 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90568.1 - 3.9e-43 140.5 24.2 5e-05 23.4 0.0 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 EAX90568.1 - 1.3e-34 117.1 14.2 0.00012 22.4 0.0 10.2 9 1 0 9 9 9 8 Ankyrin repeat PDR_CDR PF06422.12 EAX90568.1 - 0.059 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 CDR ABC transporter DivIC PF04977.15 EAX90569.1 - 0.11 12.3 41.9 2.2 8.1 1.5 5.8 2 1 4 6 6 6 0 Septum formation initiator DUF4407 PF14362.6 EAX90569.1 - 0.23 10.8 26.0 1.5 8.1 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EAX90569.1 - 3.4 8.2 49.3 1.3 9.5 6.1 5.4 3 1 2 5 5 5 0 Cell division protein ZapB Erv26 PF04148.13 EAX90571.1 - 0.023 14.5 1.9 0.034 14.0 0.1 2.0 2 1 1 3 3 3 0 Transmembrane adaptor Erv26 Reticulon PF02453.17 EAX90571.1 - 0.12 12.3 6.5 0.76 9.7 6.1 2.3 1 1 1 2 2 2 0 Reticulon PKD PF00801.20 EAX90572.1 - 0.08 12.8 0.2 0.14 12.0 0.2 1.5 1 1 0 1 1 1 0 PKD domain Viral_P18 PF04521.13 EAX90574.1 - 0.0053 16.5 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein ETRAMP PF09716.10 EAX90575.1 - 0.0004 20.4 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) UPF0258 PF06789.12 EAX90575.1 - 0.0091 16.1 1.8 0.015 15.5 1.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) DUF4448 PF14610.6 EAX90575.1 - 0.03 14.1 0.1 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LRR_5 PF13306.6 EAX90575.1 - 0.032 14.2 1.1 0.047 13.6 1.1 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) TMEM154 PF15102.6 EAX90575.1 - 0.036 14.0 2.5 0.05 13.5 2.2 1.5 1 1 0 1 1 1 0 TMEM154 protein family Trypan_PARP PF05887.11 EAX90575.1 - 0.048 13.6 37.1 0.12 12.3 29.0 2.4 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Orf78 PF06024.12 EAX90575.1 - 0.054 13.8 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 EAX90575.1 - 1 9.7 5.4 1.6 9.1 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) LRR_5 PF13306.6 EAX90576.1 - 2.5e-33 114.8 7.1 4.4e-18 65.5 2.3 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90576.1 - 2.1e-06 27.4 0.0 1.7 8.5 0.0 4.4 2 2 2 4 4 4 3 Leucine rich repeat Prok-RING_4 PF14447.6 EAX90577.1 - 0.0005 19.9 13.8 0.0011 18.8 13.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAX90577.1 - 0.00062 19.7 19.4 0.0016 18.4 19.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 EAX90577.1 - 0.0028 17.5 6.3 0.0063 16.4 6.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EAX90577.1 - 0.0075 16.3 14.3 0.086 12.9 8.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAX90577.1 - 0.01 15.6 16.0 0.043 13.7 16.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX90577.1 - 0.05 13.9 16.0 0.15 12.4 16.0 1.9 1 0 0 1 1 1 0 Ring finger domain TSNAXIP1_N PF15739.5 EAX90577.1 - 0.062 13.7 0.3 0.062 13.7 0.3 3.5 4 0 0 4 4 4 0 Translin-associated factor X-interacting N-terminus LOH1CR12 PF10158.9 EAX90577.1 - 0.46 10.5 5.3 1 9.4 0.0 3.8 3 1 0 4 4 4 0 Tumour suppressor protein NPV_P10 PF05531.12 EAX90577.1 - 0.53 10.8 8.2 1.5 9.3 0.0 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 EAX90577.1 - 0.74 9.7 3.2 17 5.3 0.2 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 zf-RING_11 PF17123.5 EAX90577.1 - 1.1 9.1 10.9 1.8 8.4 0.4 2.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 EAX90577.1 - 1.6 8.7 16.6 12 5.9 17.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.15 EAX90577.1 - 2 8.2 7.6 1.3 8.8 1.3 3.5 3 0 0 3 3 3 0 Septum formation initiator BCDHK_Adom3 PF10436.9 EAX90577.1 - 3.2 7.5 12.2 0.86 9.4 0.2 3.9 2 1 1 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF1664 PF07889.12 EAX90577.1 - 3.6 7.7 14.1 3.7 7.6 0.8 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 EAX90577.1 - 7.2 6.9 21.0 2.6 8.3 0.7 5.0 4 1 1 5 5 5 0 Tho complex subunit 7 zf-C3HC4_4 PF15227.6 EAX90577.1 - 9.4 6.5 13.1 19 5.5 9.6 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DENN PF02141.21 EAX90578.1 - 0.011 15.7 1.2 0.063 13.2 0.2 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain DHC_N2 PF08393.13 EAX90579.1 - 2.2e-59 201.6 12.2 2.2e-59 201.6 12.2 7.0 8 0 0 8 8 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EAX90579.1 - 3.3e-17 62.4 13.3 7.2e-16 58.1 0.2 5.3 5 0 0 5 5 5 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EAX90579.1 - 2.2e-12 46.9 3.2 1.2e-10 41.2 2.5 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 EAX90579.1 - 6.8e-07 28.6 0.0 0.0023 17.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EAX90579.1 - 0.00015 21.4 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 EAX90579.1 - 0.00042 20.8 8.8 0.096 13.1 0.0 5.4 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX90579.1 - 0.00042 20.6 0.0 0.59 10.4 0.0 3.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAX90579.1 - 0.00045 20.6 0.0 0.23 11.8 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain Latarcin PF10279.9 EAX90579.1 - 0.00049 20.4 0.0 68 4.0 1.0 5.8 5 2 0 5 5 3 0 Latarcin precursor AAA_5 PF07728.14 EAX90579.1 - 0.0023 17.9 0.0 0.036 14.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Macscav_rec PF03523.13 EAX90579.1 - 0.017 15.0 0.1 0.22 11.5 0.1 3.1 1 0 0 1 1 1 0 Macrophage scavenger receptor SMC_N PF02463.19 EAX90579.1 - 0.029 13.8 0.0 7.5 5.9 0.0 3.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 EAX90579.1 - 0.035 14.1 4.4 0.31 11.0 0.0 4.1 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAX90579.1 - 0.06 13.1 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EAX90579.1 - 0.39 11.1 3.3 6.5 7.2 0.1 4.1 2 1 0 2 2 2 0 RNA helicase Dynein_AAA_lid PF17852.1 EAX90579.1 - 0.86 9.7 4.4 1.9 8.6 0.1 4.0 4 0 0 4 4 2 0 Dynein heavy chain AAA lid domain SHE3 PF17078.5 EAX90581.1 - 0.02 14.6 16.3 0.028 14.1 16.3 1.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TetR_C_24 PF17932.1 EAX90581.1 - 0.023 14.9 0.7 5.1 7.4 0.1 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PKK PF12474.8 EAX90581.1 - 0.023 14.8 12.1 0.22 11.7 0.3 2.4 1 1 0 2 2 2 0 Polo kinase kinase Phasin PF05597.11 EAX90581.1 - 0.027 14.4 2.6 0.032 14.2 2.6 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FAM184 PF15665.5 EAX90581.1 - 0.04 13.7 13.3 0.08 12.7 13.3 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Enterotoxin_b PF01376.18 EAX90581.1 - 0.046 13.9 1.0 0.079 13.2 0.5 1.6 1 1 1 2 2 2 0 Heat-labile enterotoxin beta chain DUF2130 PF09903.9 EAX90581.1 - 0.05 12.9 13.4 0.06 12.6 13.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Sds3 PF08598.11 EAX90581.1 - 0.14 12.1 15.6 0.47 10.4 6.3 2.0 1 1 1 2 2 2 0 Sds3-like Ax_dynein_light PF10211.9 EAX90581.1 - 0.17 11.8 13.0 0.21 11.5 13.0 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DUF1640 PF07798.11 EAX90581.1 - 0.23 11.5 14.9 0.42 10.6 14.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YlqD PF11068.8 EAX90581.1 - 0.31 11.4 11.9 0.63 10.4 11.6 1.6 1 1 0 1 1 1 0 YlqD protein Nbl1_Borealin_N PF10444.9 EAX90581.1 - 3.3 7.4 9.1 14 5.4 0.1 2.6 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal HOOK PF05622.12 EAX90582.1 - 0.00025 19.4 37.5 0.00034 18.9 37.5 1.1 1 0 0 1 1 1 1 HOOK protein Tropomyosin_1 PF12718.7 EAX90582.1 - 0.00035 20.7 43.6 0.006 16.7 11.9 3.2 1 1 2 3 3 3 2 Tropomyosin like Fib_alpha PF08702.10 EAX90582.1 - 0.05 13.8 34.3 0.24 11.6 13.8 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EAX90582.1 - 0.079 11.8 42.4 0.12 11.2 20.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TACC_C PF05010.14 EAX90582.1 - 0.37 10.5 37.6 0.84 9.4 37.5 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_MLP1_2 PF07926.12 EAX90582.1 - 0.51 10.4 37.2 3.4 7.7 10.4 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 EAX90582.1 - 0.54 9.5 32.7 0.14 11.4 9.8 2.7 1 1 1 2 2 2 0 TMPIT-like protein CREPT PF16566.5 EAX90582.1 - 0.8 9.9 29.3 0.41 10.8 9.3 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2564 PF10819.8 EAX90582.1 - 0.93 9.9 7.3 3.5 8.1 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) HMMR_N PF15905.5 EAX90582.1 - 0.98 8.8 43.8 2.6 7.4 21.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 EAX90582.1 - 2.8 8.3 34.3 0.89 10.0 5.9 3.9 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Exonuc_VII_L PF02601.15 EAX90582.1 - 3.2 7.2 31.6 1.6 8.2 16.5 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 EAX90582.1 - 4.6 7.9 28.6 4.7 7.8 6.2 3.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal GAS PF13851.6 EAX90582.1 - 4.8 6.5 41.2 0.63 9.4 13.8 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EAX90582.1 - 5.5 6.0 35.9 4.4 6.3 27.3 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bacillus_HBL PF05791.11 EAX90582.1 - 7.4 6.4 24.2 0.21 11.4 3.6 3.3 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DCB PF16213.5 EAX90582.1 - 7.5 6.2 17.2 4.1 7.0 3.9 2.3 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Rootletin PF15035.6 EAX90583.1 - 0.0069 16.4 18.3 0.0069 16.4 18.3 6.9 2 1 3 5 5 5 1 Ciliary rootlet component, centrosome cohesion PuR_N PF09182.10 EAX90583.1 - 5.4 7.0 10.5 1.2 9.1 0.6 4.0 3 1 1 4 4 4 0 Bacterial purine repressor, N-terminal DUF724 PF05266.14 EAX90584.1 - 0.00041 20.2 5.4 0.00041 20.2 5.4 1.6 1 1 1 2 2 1 1 Protein of unknown function (DUF724) CREPT PF16566.5 EAX90584.1 - 0.00059 20.0 12.6 0.0021 18.3 2.9 2.2 1 1 1 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 EAX90584.1 - 0.00089 19.3 1.6 0.00089 19.3 1.6 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 EAX90584.1 - 0.0013 17.7 9.7 0.0018 17.2 9.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 EAX90584.1 - 0.0014 16.9 10.4 0.0018 16.6 9.5 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 EAX90584.1 - 0.0033 17.8 11.2 0.024 15.0 1.7 3.6 2 1 1 4 4 3 2 Flagella accessory protein C (FlaC) Filament PF00038.21 EAX90584.1 - 0.0053 16.4 6.4 0.0076 15.9 5.2 1.7 1 1 1 2 2 2 1 Intermediate filament protein DUF4407 PF14362.6 EAX90584.1 - 0.0054 16.1 5.0 0.0069 15.8 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) OmpH PF03938.14 EAX90584.1 - 0.0064 16.8 8.7 0.06 13.7 5.1 2.4 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Macoilin PF09726.9 EAX90584.1 - 0.0064 15.1 5.5 0.0064 15.1 5.5 1.8 1 1 1 2 2 2 1 Macoilin family DUF812 PF05667.11 EAX90584.1 - 0.0074 15.2 7.3 0.0092 14.9 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HMMR_N PF15905.5 EAX90584.1 - 0.0079 15.7 12.7 0.0097 15.4 12.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal AIP3 PF03915.13 EAX90584.1 - 0.0091 15.1 8.3 0.013 14.6 8.3 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 YojJ PF10372.9 EAX90584.1 - 0.0095 16.0 3.1 2.4 8.3 0.6 2.6 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus KASH_CCD PF14662.6 EAX90584.1 - 0.0096 15.8 11.9 0.025 14.4 11.9 1.8 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 EAX90584.1 - 0.0097 16.1 8.2 0.097 12.9 3.4 2.4 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF4349 PF14257.6 EAX90584.1 - 0.012 15.1 2.6 0.015 14.7 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ZapB PF06005.12 EAX90584.1 - 0.014 15.8 0.5 0.014 15.8 0.5 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 EAX90584.1 - 0.014 15.9 10.3 0.12 12.9 2.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EAX90584.1 - 0.019 15.5 5.7 0.019 15.5 5.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EAX90584.1 - 0.023 13.8 7.5 0.043 12.9 7.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EAX90584.1 - 0.028 14.0 3.9 0.033 13.8 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 EAX90584.1 - 0.029 13.9 10.7 0.032 13.8 3.5 2.2 1 1 1 2 2 2 0 fzo-like conserved region HOOK PF05622.12 EAX90584.1 - 0.032 12.4 11.5 0.054 11.6 11.4 1.4 1 1 0 1 1 1 0 HOOK protein tRNA-synt_His PF13393.6 EAX90584.1 - 0.034 13.4 3.2 0.082 12.2 3.2 1.7 1 1 0 1 1 1 0 Histidyl-tRNA synthetase Prominin PF05478.11 EAX90584.1 - 0.035 12.1 7.1 0.051 11.5 7.1 1.3 1 0 0 1 1 1 0 Prominin HALZ PF02183.18 EAX90584.1 - 0.038 14.2 9.3 0.12 12.7 1.9 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4472 PF14739.6 EAX90584.1 - 0.038 14.7 9.9 0.12 13.1 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Sec34 PF04136.15 EAX90584.1 - 0.039 13.8 15.2 0.074 12.9 4.4 3.0 1 1 3 4 4 3 0 Sec34-like family PspA_IM30 PF04012.12 EAX90584.1 - 0.047 13.3 6.4 0.12 12.0 6.4 1.8 1 1 0 1 1 1 0 PspA/IM30 family Spc24 PF08286.11 EAX90584.1 - 0.049 13.9 10.5 0.28 11.5 5.0 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 EAX90584.1 - 0.057 13.9 16.3 0.31 11.5 6.3 3.0 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 EAX90584.1 - 0.059 13.8 8.3 0.052 14.0 4.0 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4795 PF16043.5 EAX90584.1 - 0.061 12.9 13.2 0.71 9.4 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 EAX90584.1 - 0.063 13.7 9.5 0.12 12.8 9.3 1.6 1 1 0 1 1 1 0 Fez1 DUF641 PF04859.12 EAX90584.1 - 0.071 13.4 6.3 0.16 12.3 6.1 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) IFT57 PF10498.9 EAX90584.1 - 0.075 12.0 11.7 0.43 9.5 11.8 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 EAX90584.1 - 0.085 12.3 8.2 0.12 11.9 8.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MIF4G_like_2 PF09090.11 EAX90584.1 - 0.093 12.2 5.1 0.06 12.8 3.2 1.5 1 1 0 1 1 1 0 MIF4G like V_ATPase_I PF01496.19 EAX90584.1 - 0.094 10.6 4.1 0.11 10.4 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CdvA PF18822.1 EAX90584.1 - 0.099 12.5 11.7 0.55 10.1 1.3 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Laminin_II PF06009.12 EAX90584.1 - 0.1 12.6 10.3 0.025 14.6 6.5 1.8 1 1 1 2 2 2 0 Laminin Domain II UPF0242 PF06785.11 EAX90584.1 - 0.1 12.7 13.4 0.055 13.6 7.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 EAX90584.1 - 0.11 12.9 12.1 2.9 8.4 4.9 3.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF3552 PF12072.8 EAX90584.1 - 0.15 11.5 8.6 0.12 11.8 7.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF16 PF01519.16 EAX90584.1 - 0.15 12.5 11.1 0.12 12.9 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Muted PF14942.6 EAX90584.1 - 0.16 12.3 11.1 0.46 10.8 11.1 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4226 PF10774.9 EAX90584.1 - 0.16 12.2 2.4 0.15 12.4 0.6 1.8 2 1 1 3 3 1 0 Domain of unknown function (DUF4226) TEX13 PF15186.6 EAX90584.1 - 0.18 11.5 7.5 0.48 10.1 1.7 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Fib_alpha PF08702.10 EAX90584.1 - 0.2 11.9 13.0 0.41 10.8 7.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EAX90584.1 - 0.2 11.7 12.6 0.079 13.0 8.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCC-bdg_PDZ PF10506.9 EAX90584.1 - 0.21 11.6 4.2 0.9 9.6 0.2 3.1 2 1 1 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AATF-Che1 PF13339.6 EAX90584.1 - 0.23 12.1 8.6 0.38 11.4 8.6 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Cluap1 PF10234.9 EAX90584.1 - 0.24 10.8 13.1 2.1 7.7 13.0 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 LMBR1 PF04791.16 EAX90584.1 - 0.3 9.9 5.2 0.33 9.8 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DHR10 PF18595.1 EAX90584.1 - 0.32 11.1 11.7 0.22 11.6 3.5 3.0 2 1 0 3 3 2 0 Designed helical repeat protein 10 domain UPF0184 PF03670.13 EAX90584.1 - 0.33 11.4 6.2 1.3 9.5 3.3 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) ADIP PF11559.8 EAX90584.1 - 0.37 10.9 14.0 0.05 13.7 6.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.8 EAX90584.1 - 0.38 10.4 6.3 0.23 11.1 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TolA_bind_tri PF16331.5 EAX90584.1 - 0.42 10.7 7.9 0.05 13.7 2.4 2.3 2 1 0 2 2 1 0 TolA binding protein trimerisation DivIC PF04977.15 EAX90584.1 - 0.49 10.2 5.1 0.53 10.1 3.1 2.1 1 1 0 1 1 1 0 Septum formation initiator Fmp27_WPPW PF10359.9 EAX90584.1 - 0.5 9.1 11.7 0.056 12.3 5.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Nup54 PF13874.6 EAX90584.1 - 0.53 10.4 5.1 2.8 8.0 5.1 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Vps51 PF08700.11 EAX90584.1 - 0.57 10.3 10.3 25 5.1 10.2 2.8 1 1 0 1 1 1 0 Vps51/Vps67 DUF489 PF04356.12 EAX90584.1 - 0.6 10.1 3.5 0.92 9.5 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Tropomyosin_1 PF12718.7 EAX90584.1 - 0.6 10.3 12.4 0.14 12.4 7.9 2.1 2 1 0 2 2 1 0 Tropomyosin like Ax_dynein_light PF10211.9 EAX90584.1 - 0.63 10.0 10.2 0.27 11.1 4.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain CLZ PF16526.5 EAX90584.1 - 0.67 10.4 12.6 0.91 9.9 2.5 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AKNA PF12443.8 EAX90584.1 - 0.68 10.6 14.1 0.23 12.1 1.0 3.5 2 1 1 4 4 3 0 AT-hook-containing transcription factor DUF2203 PF09969.9 EAX90584.1 - 0.77 10.5 4.3 4.5 8.0 1.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 EAX90584.1 - 0.79 10.4 12.3 0.76 10.4 6.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF4404 PF14357.6 EAX90584.1 - 0.89 10.2 11.1 1.2 9.8 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Occludin_ELL PF07303.13 EAX90584.1 - 0.96 10.2 8.3 5 7.9 5.2 2.9 1 1 2 3 3 1 0 Occludin homology domain DUF3450 PF11932.8 EAX90584.1 - 0.97 8.7 9.8 0.32 10.3 5.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EAX90584.1 - 0.98 8.6 10.5 0.65 9.2 2.2 2.0 1 1 2 3 3 3 0 TMPIT-like protein FliD_N PF02465.18 EAX90584.1 - 1 10.1 13.7 6.5 7.5 6.1 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2730 PF10805.8 EAX90584.1 - 1.5 8.9 7.8 2.8 8.1 6.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HIP1_clath_bdg PF16515.5 EAX90584.1 - 1.8 9.2 13.0 2.2 8.9 5.2 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0449 PF15136.6 EAX90584.1 - 2 9.0 11.2 32 5.1 11.2 2.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 STAT_alpha PF01017.20 EAX90584.1 - 2.1 8.2 12.9 0.4 10.6 5.7 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain FapA PF03961.13 EAX90584.1 - 2.2 6.8 11.5 2 6.9 1.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF848 PF05852.11 EAX90584.1 - 2.2 8.4 11.3 4.5 7.4 1.1 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 EAX90584.1 - 2.3 8.2 14.9 1.4 8.9 5.7 3.3 1 1 1 2 2 2 0 Prefoldin subunit Phage_GPO PF05929.11 EAX90584.1 - 2.4 7.7 10.4 4.4 6.9 10.4 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Jnk-SapK_ap_N PF09744.9 EAX90584.1 - 2.4 8.3 12.6 4 7.6 5.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 XhlA PF10779.9 EAX90584.1 - 3.1 8.1 12.4 11 6.3 7.8 3.1 1 1 1 2 2 2 0 Haemolysin XhlA DUF4446 PF14584.6 EAX90584.1 - 4.2 7.3 8.3 23 4.9 6.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) bZIP_1 PF00170.21 EAX90584.1 - 4.3 7.5 14.6 0.16 12.1 2.2 3.3 3 1 1 4 4 3 0 bZIP transcription factor CENP-H PF05837.12 EAX90584.1 - 6.6 7.2 12.6 1.4 9.4 6.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) CC2-LZ PF16516.5 EAX90584.1 - 8.6 6.8 12.8 2.8 8.3 0.6 2.8 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SlyX PF04102.12 EAX90584.1 - 9 7.0 7.8 3.7 8.2 1.2 3.1 2 1 1 3 3 2 0 SlyX Ank_2 PF12796.7 EAX90585.1 - 1.5e-41 140.9 6.0 1.2e-16 61.1 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90585.1 - 1.6e-38 129.5 7.1 1.1e-08 35.1 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX90585.1 - 1.7e-38 130.5 4.1 4.7e-12 46.2 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90585.1 - 4e-37 125.8 5.3 1.1e-11 44.7 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90585.1 - 1e-35 117.7 4.7 3.2e-07 30.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX90586.1 - 5.6e-36 123.0 7.2 1.9e-15 57.2 0.4 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90586.1 - 8.6e-26 90.0 0.2 1.7e-09 38.0 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90586.1 - 3e-22 76.3 0.2 2.8e-05 24.2 0.1 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EAX90586.1 - 1.3e-19 69.7 1.3 7.6e-05 23.0 0.1 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX90586.1 - 1.1e-18 67.1 0.1 0.011 16.1 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX90586.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Colon cancer-associated protein Mic1-like DUF3447 PF11929.8 EAX90587.1 - 7.8e-21 73.8 5.7 7.8e-21 73.8 5.7 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) KIAA1430 PF13879.6 EAX90588.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DNA_pol_B_2 PF03175.13 EAX90590.1 - 2e-10 40.1 4.2 2e-10 40.1 4.2 2.3 1 1 1 2 2 2 2 DNA polymerase type B, organellar and viral Isy1 PF06246.12 EAX90590.1 - 0.13 11.8 0.6 0.25 10.9 0.6 1.5 1 1 0 1 1 1 0 Isy1-like splicing family KilA-N PF04383.13 EAX90591.1 - 1.6e-14 53.7 0.2 3.2e-14 52.7 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX90592.1 - 5.6e-154 510.6 13.0 7.1e-154 510.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX90592.1 - 0.44 11.1 2.7 0.43 11.1 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) RPA43_OB PF17875.1 EAX90593.1 - 1.4e-05 25.7 0.0 2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EAX90593.1 - 0.0066 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EAX90593.1 - 0.066 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 S1 RNA binding domain Thioredoxin PF00085.20 EAX90594.1 - 2.1e-14 53.3 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX90594.1 - 0.00013 22.4 0.1 0.0027 18.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX90594.1 - 0.0018 18.6 0.0 0.0078 16.5 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EAX90594.1 - 0.0025 17.7 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EAX90594.1 - 0.0025 18.0 0.0 0.0056 16.9 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 EAX90594.1 - 0.0037 17.4 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EAX90594.1 - 0.006 16.0 0.0 0.006 16.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EAX90594.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Phage_Mu_Gp45 PF06890.12 EAX90594.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage Mu Gp45 protein Thioredoxin_9 PF14595.6 EAX90594.1 - 0.025 14.3 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 EAX90594.1 - 0.048 13.4 0.1 0.057 13.1 0.1 1.3 1 1 0 1 1 1 0 Redoxin RRM_1 PF00076.22 EAX90596.1 - 2.4e-05 24.0 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX90596.1 - 0.1 12.6 0.2 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_2 PF14608.6 EAX90596.1 - 0.13 12.8 0.9 0.13 12.8 0.9 2.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EAX90596.1 - 0.16 12.7 1.7 0.29 11.9 1.7 1.5 1 0 0 1 1 1 0 Torus domain Myb_DNA-binding PF00249.31 EAX90598.1 - 4.6e-21 74.8 0.3 1.2e-09 38.2 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90598.1 - 5.5e-20 71.4 2.6 1.8e-15 56.9 0.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX90598.1 - 0.0071 16.2 0.2 0.15 12.0 0.0 2.4 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX90598.1 - 0.085 13.2 0.9 0.34 11.3 0.4 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EAX90598.1 - 0.12 12.4 0.1 8.1 6.5 0.1 2.2 1 1 1 2 2 2 0 SLIDE Dimer_Tnp_hAT PF05699.14 EAX90599.1 - 6.5e-07 29.1 0.1 7.9e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GPS2_interact PF15784.5 EAX90601.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX90601.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX90602.1 - 0.041 13.9 8.7 0.064 13.2 8.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX90603.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX90604.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX90604.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX90605.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX90605.1 - 0.13 12.3 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MULE PF10551.9 EAX90606.1 - 1.5e-12 47.7 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain RabGAP-TBC PF00566.18 EAX90608.1 - 1.2e-15 57.8 2.6 1.2e-15 57.8 2.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4108 PF13390.6 EAX90610.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX90611.1 - 1.1e-06 28.3 2.8 1.1e-06 28.3 2.8 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90611.1 - 6.9e-05 23.1 0.2 0.00041 20.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX90611.1 - 0.0002 21.4 1.5 0.00044 20.3 1.5 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90611.1 - 0.0012 18.6 0.1 0.0025 17.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EAX90611.1 - 0.0037 16.9 0.4 0.018 14.7 0.5 1.9 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX90611.1 - 0.0047 16.7 0.1 0.57 9.9 0.0 2.6 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_11 PF13086.6 EAX90611.1 - 0.013 15.3 0.4 0.024 14.4 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX90611.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX90611.1 - 0.15 11.6 0.0 0.7 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 EAX90611.1 - 0.28 10.9 1.3 0.32 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX90611.1 - 1.9 8.7 8.2 11 6.2 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX90612.1 - 1.5e-24 86.8 5.0 2.2e-24 86.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX90612.1 - 0.12 12.8 0.4 0.31 11.5 0.4 1.7 1 1 0 1 1 1 0 Cell division protein ZapB PTR PF12789.7 EAX90613.1 - 9.1e-17 60.9 1.9 9.1e-17 60.9 1.9 3.6 4 1 0 4 4 4 1 Phage tail repeat like DUF4795 PF16043.5 EAX90613.1 - 0.0026 17.4 1.2 0.0031 17.1 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX90613.1 - 0.15 12.6 1.4 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Myb_DNA-binding PF00249.31 EAX90614.1 - 1.6e-28 98.6 0.6 1.8e-14 53.6 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90614.1 - 1.8e-28 98.6 0.9 5.3e-19 68.2 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX90614.1 - 2.9e-09 36.7 0.7 9.4e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX90614.1 - 3.7e-05 23.7 0.1 0.012 15.6 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX90614.1 - 0.00047 20.5 1.0 0.16 12.3 0.3 3.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX90614.1 - 0.0058 16.8 0.1 0.082 13.1 0.0 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EAX90614.1 - 0.057 13.7 0.2 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Aerolysin PF01117.20 EAX90615.1 - 0.054 12.7 0.7 0.11 11.6 0.7 1.5 1 0 0 1 1 1 0 Aerolysin toxin DUF4107 PF13389.6 EAX90616.1 - 1.7e-71 239.6 3.8 2.3e-71 239.2 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Gly-zipper_Omp PF13488.6 EAX90619.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX90619.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX90619.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX90619.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX90619.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2996 PF11210.8 EAX90620.1 - 0.11 12.9 5.5 0.93 10.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2996) ChlamPMP_M PF07548.11 EAX90620.1 - 6.4 6.7 8.2 5.3 6.9 1.6 2.5 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain LRR_5 PF13306.6 EAX90621.1 - 1.7e-36 125.0 28.6 1.4e-21 76.7 12.6 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90621.1 - 0.00047 19.9 0.1 0.039 13.7 0.0 3.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EAX90621.1 - 0.06 13.8 1.6 2.7 8.5 0.0 3.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX90622.1 - 4.5e-84 278.8 85.9 7.1e-25 87.4 11.9 4.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90622.1 - 6.5e-19 67.5 1.3 6.6e-05 22.6 0.0 7.4 6 2 1 7 7 7 5 Leucine rich repeat DUF4372 PF14294.6 EAX90622.1 - 0.14 12.4 0.3 21 5.4 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4372) LRR_5 PF13306.6 EAX90623.1 - 1.2e-41 141.7 34.9 3e-18 66.0 8.2 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90623.1 - 3e-10 39.7 0.0 3.6e-05 23.4 0.0 5.3 4 2 2 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EAX90623.1 - 1.4e-05 25.3 1.2 8 7.0 0.0 6.1 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) DUF4372 PF14294.6 EAX90623.1 - 0.11 12.7 0.0 12 6.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4372) LRR_5 PF13306.6 EAX90624.1 - 5.8e-126 414.3 94.2 1.5e-27 96.1 2.4 6.0 2 2 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90624.1 - 3.9e-14 52.2 8.0 0.011 15.5 0.1 7.0 7 1 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EAX90624.1 - 0.37 11.3 13.7 7.4 7.1 0.1 6.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF1043 PF06295.12 EAX90625.1 - 0.032 14.2 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX90626.1 - 0.034 14.5 0.3 0.046 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX90627.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Collagen_bind_2 PF12904.7 EAX90629.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase LRR_5 PF13306.6 EAX90631.1 - 9.4e-163 533.2 153.3 2.5e-27 95.4 16.3 8.1 1 1 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90631.1 - 5.2e-27 93.4 7.4 0.00015 21.5 0.0 11.7 10 2 2 12 12 12 7 Leucine rich repeat LRR_4 PF12799.7 EAX90631.1 - 3.1e-06 27.4 18.0 3 8.4 0.0 11.0 8 3 5 13 13 13 2 Leucine Rich repeats (2 copies) SVWC PF15430.6 EAX90631.1 - 0.01 16.1 0.4 4.6 7.6 0.1 3.4 2 0 0 2 2 2 1 Single domain von Willebrand factor type C DUF5300 PF17224.3 EAX90631.1 - 0.33 11.3 2.7 0.77 10.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) DUF4108 PF13390.6 EAX90632.1 - 9.7e-63 210.4 7.6 1.1e-62 210.2 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_5 PF13306.6 EAX90634.1 - 9.3e-48 161.4 33.7 6.6e-17 61.7 4.2 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90634.1 - 7.5e-17 60.9 3.5 0.00045 19.9 0.0 5.8 2 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAX90634.1 - 0.00074 19.9 10.8 8.1 7.0 0.0 5.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX90634.1 - 0.28 11.9 3.6 12 7.0 0.7 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat PAP2 PF01569.21 EAX90635.1 - 9.3e-25 87.0 4.0 1.6e-24 86.2 1.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EAX90635.1 - 0.0029 18.1 1.6 0.0029 18.1 1.6 2.7 2 0 0 2 2 2 1 PAP2 superfamily C-terminal ESPR PF13018.6 EAX90635.1 - 0.065 13.0 0.0 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system PAP2_3 PF14378.6 EAX90635.1 - 0.092 12.4 5.3 0.23 11.1 5.3 1.6 1 1 0 1 1 1 0 PAP2 superfamily Wzy_C PF04932.15 EAX90635.1 - 0.16 11.6 6.3 4.6 6.9 0.0 2.5 2 1 0 2 2 2 0 O-Antigen ligase DUF2207 PF09972.9 EAX90635.1 - 0.35 9.6 2.4 3.5 6.3 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) VKOR PF07884.14 EAX90635.1 - 1.7 8.8 8.7 0.67 10.1 0.6 2.3 1 1 1 2 2 2 0 Vitamin K epoxide reductase family ASH PF15780.5 EAX90636.1 - 2.4e-39 133.5 58.7 0.00016 21.8 0.5 20.1 19 2 0 20 20 20 13 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EAX90636.1 - 7.8e-17 61.3 5.1 0.43 10.8 0.0 11.0 13 0 0 13 13 13 4 Flagellar-associated PapD-like AAA_18 PF13238.6 EAX90636.1 - 4.8e-16 59.5 1.2 4.8e-16 59.5 1.2 2.3 1 1 1 2 2 2 1 AAA domain Motile_Sperm PF00635.26 EAX90636.1 - 3.2e-13 49.5 49.0 0.0023 17.8 0.2 16.2 18 0 0 18 18 18 5 MSP (Major sperm protein) domain DUF1573 PF07610.11 EAX90636.1 - 5.9e-10 39.0 46.6 0.13 12.3 0.0 17.2 18 2 0 18 18 18 4 Protein of unknown function (DUF1573) SKI PF01202.22 EAX90636.1 - 0.13 12.4 3.1 0.99 9.5 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase Thioredoxin PF00085.20 EAX90637.1 - 0.0033 17.4 0.1 0.004 17.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2847 PF11009.8 EAX90637.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_7 PF13899.6 EAX90637.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EAX90637.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EAX90637.1 - 0.045 14.1 0.2 0.14 12.5 0.1 1.7 2 1 0 2 2 2 0 Thioredoxin-like Pkinase PF00069.25 EAX90638.1 - 2.8e-60 203.9 0.5 3.9e-60 203.5 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90638.1 - 3.9e-33 114.8 0.4 5.1e-32 111.2 0.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX90638.1 - 1.1e-08 35.3 0.0 4.5e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EAX90638.1 - 0.00015 21.4 0.0 0.00015 21.4 0.0 1.9 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.14 EAX90638.1 - 0.00042 19.7 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX90638.1 - 0.019 14.3 0.0 0.31 10.3 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Herpes_UL37_2 PF07413.11 EAX90638.1 - 0.04 13.1 0.3 0.066 12.4 0.3 1.3 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 START PF01852.19 EAX90640.1 - 9.8e-11 41.5 0.0 2.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 START domain S-layer PF07752.11 EAX90640.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 S-layer protein PSP PF04046.16 EAX90641.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90642.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90643.1 - 0.073 13.5 0.9 0.15 12.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX90644.1 - 7.4e-51 170.1 32.6 1.6e-33 114.6 16.1 4.0 3 2 2 5 5 4 2 Phage tail repeat like Poxvirus_B22R_C PF13168.6 EAX90644.1 - 0.015 14.8 0.1 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF4116 PF13475.6 EAX90644.1 - 0.072 12.8 0.1 0.25 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX90646.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90647.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP F5_F8_type_C PF00754.25 EAX90648.1 - 1.8e-06 28.1 0.6 3.3e-06 27.2 0.6 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 EAX90648.1 - 1e-05 25.5 0.2 3.3e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Paralemmin PF03285.15 EAX90649.1 - 0.034 13.7 1.4 0.034 13.7 1.4 4.0 3 1 1 4 4 4 0 Paralemmin Cob_adeno_trans PF01923.18 EAX90649.1 - 0.12 12.5 19.4 0.19 11.9 1.9 3.8 1 1 3 4 4 4 0 Cobalamin adenosyltransferase TACC_C PF05010.14 EAX90649.1 - 0.26 11.1 45.4 0.051 13.3 23.3 3.4 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Golgin_A5 PF09787.9 EAX90649.1 - 0.57 9.6 45.1 0.23 10.9 23.8 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spike_torovirin PF17072.5 EAX90649.1 - 0.7 6.9 3.6 0.93 6.5 3.6 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein CCDC-167 PF15188.6 EAX90649.1 - 1.4 9.3 35.5 0.19 12.1 5.0 4.1 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 HrpB2 PF09487.10 EAX90649.1 - 2.9 8.4 9.0 0.67 10.4 0.1 3.5 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB2) YlqD PF11068.8 EAX90649.1 - 4.8 7.6 34.0 0.47 10.8 5.9 3.7 2 1 2 4 4 4 0 YlqD protein TPR_MLP1_2 PF07926.12 EAX90649.1 - 8.5 6.5 43.4 0.06 13.4 15.3 4.9 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Muted PF14942.6 EAX90649.1 - 9.5 6.6 43.7 0.6 10.4 12.6 3.4 1 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Abi_C PF14355.6 EAX90649.1 - 9.6 6.4 9.7 4 7.6 0.2 4.0 4 0 0 4 4 4 0 Abortive infection C-terminus Ribosomal_L21e PF01157.18 EAX90650.1 - 2.3e-38 130.1 0.3 3.3e-38 129.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Ank_2 PF12796.7 EAX90651.1 - 8e-14 52.0 2.7 8.6e-09 35.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90651.1 - 5.7e-08 32.9 0.2 0.00083 19.6 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX90651.1 - 1e-07 32.3 1.2 0.0002 21.9 0.0 4.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90651.1 - 7.2e-07 29.1 6.9 0.29 11.8 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 EAX90651.1 - 2.4e-06 27.4 0.4 2.4e-06 27.4 0.4 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX90651.1 - 0.0012 19.2 0.9 0.77 10.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat ubiquitin PF00240.23 EAX90653.1 - 7.7e-07 28.8 0.1 1.1e-06 28.3 0.1 1.2 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EAX90653.1 - 0.005 17.2 0.0 0.0057 17.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Mito_fiss_reg PF05308.11 EAX90654.1 - 0.0017 18.5 0.8 0.0021 18.2 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator TSC22 PF01166.18 EAX90654.1 - 0.004 17.4 2.9 0.014 15.7 0.9 2.5 2 0 0 2 2 2 1 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 EAX90654.1 - 0.0045 17.2 0.9 0.0095 16.2 0.9 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 EAX90654.1 - 0.0078 14.2 3.8 0.009 14.0 3.8 1.0 1 0 0 1 1 1 1 Prominin FlxA PF14282.6 EAX90654.1 - 0.0086 16.1 1.5 0.015 15.3 1.5 1.4 1 0 0 1 1 1 1 FlxA-like protein FlaC_arch PF05377.11 EAX90654.1 - 0.044 14.2 1.9 0.061 13.7 0.5 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EAX90654.1 - 0.052 12.6 5.4 0.061 12.4 5.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 EAX90654.1 - 0.058 14.3 3.8 0.054 14.4 2.1 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Syntaxin_2 PF14523.6 EAX90654.1 - 0.074 13.4 2.8 0.044 14.1 1.1 1.6 2 0 0 2 2 2 0 Syntaxin-like protein NuiA PF07924.11 EAX90654.1 - 0.096 13.1 1.2 0.24 11.8 0.1 1.9 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein APG6_N PF17675.1 EAX90654.1 - 0.16 12.5 3.9 0.36 11.4 3.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1192 PF06698.11 EAX90654.1 - 0.17 12.0 1.7 0.44 10.6 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4337 PF14235.6 EAX90654.1 - 0.17 12.0 1.6 0.23 11.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ZapB PF06005.12 EAX90654.1 - 0.18 12.2 4.2 0.1 13.1 2.0 1.8 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EAX90654.1 - 0.33 11.6 2.3 0.51 11.0 1.2 1.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF563 PF04577.14 EAX90655.1 - 3.8e-25 89.3 0.1 6.1e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ank_4 PF13637.6 EAX90656.1 - 3.7e-16 59.2 0.1 8e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90656.1 - 1.5e-12 47.9 0.1 1.8e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90656.1 - 2.2e-11 43.7 0.0 9.4e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX90656.1 - 1.3e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90656.1 - 1.8e-09 37.1 0.2 0.00018 21.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX90657.1 - 7.8e-68 225.1 32.5 5.4e-19 68.6 1.9 5.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90657.1 - 1.1e-63 209.0 6.8 1.7e-07 31.4 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX90657.1 - 1.1e-61 204.4 13.7 2.5e-14 53.4 0.1 8.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90657.1 - 2.1e-48 156.6 13.0 1.7e-05 24.8 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX90657.1 - 3.5e-47 157.9 14.7 2e-10 40.7 0.0 6.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX90657.1 - 4.7e-23 80.9 22.6 4.6e-22 77.7 5.5 4.6 2 1 3 5 5 5 3 Domain of unknown function (DUF3447) Importin_rep_5 PF18816.1 EAX90657.1 - 1.5e-05 25.1 0.5 3.5 8.0 0.0 4.0 3 0 0 3 3 3 2 Importin repeat Sigma70_r4_2 PF08281.12 EAX90657.1 - 0.00082 19.0 2.0 2.6 7.8 0.1 4.8 5 0 0 5 5 5 1 Sigma-70, region 4 Ribosomal_S6 PF01250.17 EAX90657.1 - 0.0026 18.0 7.5 1.1 9.6 0.1 4.9 2 1 2 5 5 5 1 Ribosomal protein S6 AAA_lid_2 PF17863.1 EAX90657.1 - 0.015 15.1 0.0 19 5.2 0.0 3.9 3 1 1 4 4 4 0 AAA lid domain BRCT PF00533.26 EAX90657.1 - 0.032 14.6 4.4 21 5.6 0.0 5.1 2 1 1 3 3 3 0 BRCA1 C Terminus (BRCT) domain DUF5064 PF16703.5 EAX90657.1 - 0.051 14.1 4.0 1.3 9.6 0.2 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5064) G5 PF07501.12 EAX90657.1 - 0.12 12.9 1.0 1.5 9.3 0.3 2.6 2 0 0 2 2 2 0 G5 domain BclA_C PF18573.1 EAX90657.1 - 0.14 12.1 0.3 1.1 9.2 0.1 2.5 3 0 0 3 3 3 0 BclA C-terminal domain RL PF17797.1 EAX90657.1 - 2.3 8.2 6.3 3.2 7.8 0.2 3.9 4 2 0 4 4 4 0 RL domain DUF3447 PF11929.8 EAX90658.1 - 3.5e-38 129.4 9.5 3.5e-38 129.4 9.5 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX90658.1 - 1.9e-28 98.4 5.8 1.3e-09 38.3 0.0 6.9 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90658.1 - 7e-27 93.8 11.6 8.3e-16 58.4 1.8 4.5 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90658.1 - 8.9e-25 86.0 5.2 1e-07 32.1 0.1 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX90658.1 - 1.2e-21 76.5 0.2 5.2e-09 36.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90658.1 - 1.2e-21 74.4 8.4 4.9e-05 23.4 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 EAX90659.1 - 7.6e-17 61.5 0.4 1.4e-09 38.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX90659.1 - 2.7e-14 52.9 1.0 5.1e-10 39.3 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX90659.1 - 2.6e-11 43.5 0.1 2.9e-11 43.4 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90659.1 - 5.1e-11 43.0 0.2 7.1e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90659.1 - 6.6e-07 29.2 1.0 0.001 19.3 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat MetallophosN PF16371.5 EAX90659.1 - 0.098 12.9 0.0 1.2 9.4 0.0 1.9 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Ank_4 PF13637.6 EAX90660.1 - 3.1e-13 49.9 0.1 4.5e-10 39.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX90660.1 - 2.3e-12 46.8 0.2 3.9e-08 33.4 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX90660.1 - 1.2e-09 38.6 0.4 1.7e-09 38.1 0.4 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90660.1 - 1.9e-07 30.8 0.1 6.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX90660.1 - 1.9e-05 24.8 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Topo_Zn_Ribbon PF08272.11 EAX90660.1 - 0.034 13.8 0.2 0.044 13.5 0.2 1.2 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like WD40 PF00400.32 EAX90661.1 - 4.1e-07 30.6 4.4 0.049 14.5 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX90661.1 - 0.00017 21.9 0.1 0.58 10.5 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX90661.1 - 0.0012 18.2 0.9 0.014 14.8 0.2 2.5 2 1 0 2 2 2 1 WD40-like domain Ribosomal_S3Ae PF01015.18 EAX90662.1 - 3e-56 190.2 3.8 3.6e-56 189.9 3.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Phage_Mu_Gam PF07352.12 EAX90663.1 - 0.0039 17.1 13.7 0.034 14.1 1.7 4.0 3 0 0 3 3 3 2 Bacteriophage Mu Gam like protein DUF1192 PF06698.11 EAX90663.1 - 0.088 12.9 2.3 8.5 6.5 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF5063 PF16702.5 EAX90663.1 - 0.098 13.0 1.8 0.31 11.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5063) DUF4200 PF13863.6 EAX90663.1 - 0.39 11.1 28.0 0.25 11.7 4.4 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) Paralemmin PF03285.15 EAX90663.1 - 0.46 10.0 10.9 0.022 14.4 1.7 2.4 2 0 0 2 2 2 0 Paralemmin PKcGMP_CC PF16808.5 EAX90663.1 - 0.47 10.3 17.7 0.19 11.6 1.8 4.0 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CHDCT2 PF08074.11 EAX90663.1 - 1.2 9.2 12.1 41 4.3 0.0 4.3 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain ISG65-75 PF11727.8 EAX90663.1 - 5.8 6.1 9.2 3 7.0 0.3 3.0 2 1 0 2 2 2 0 Invariant surface glycoprotein IP_trans PF02121.18 EAX90663.1 - 9.7 5.7 12.4 1.7 8.2 0.3 3.7 2 1 0 3 3 3 0 Phosphatidylinositol transfer protein Ank_2 PF12796.7 EAX90664.1 - 1.2e-13 51.4 0.3 5.1e-10 39.8 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90664.1 - 6.4e-11 42.6 0.5 3.3e-06 27.5 0.2 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90664.1 - 3.5e-09 36.8 0.1 3.8e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90664.1 - 9.4e-09 34.8 0.1 0.017 15.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX90664.1 - 0.00098 19.5 0.0 14 6.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 EAX90665.1 - 7.1e-49 166.5 0.0 8.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90665.1 - 1.2e-15 57.5 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX90665.1 - 0.00041 20.4 0.0 0.0011 18.9 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX90665.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3453 PF11935.8 EAX90665.1 - 0.022 14.4 1.2 2.5 7.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3453) Kinase-like PF14531.6 EAX90665.1 - 0.049 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EAX90665.1 - 0.12 12.0 0.3 0.74 9.4 0.1 2.2 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 XRN_N PF03159.18 EAX90666.1 - 8.3e-67 225.1 0.0 6.9e-65 218.8 0.0 2.3 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAX90666.1 - 2.9e-47 161.6 11.1 6e-38 130.9 1.8 2.2 1 1 1 2 2 2 2 Xrn1 helical domain XRN1_D1 PF18332.1 EAX90666.1 - 2.7e-11 43.6 0.0 6.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 EAX90666.1 - 2.1e-09 37.3 0.1 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain DUF3929 PF13066.6 EAX90666.1 - 0.2 11.8 0.6 0.49 10.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) PLD_C PF12357.8 EAX90667.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D C terminal TCR PF03638.15 EAX90667.1 - 0.44 10.9 33.6 0.17 12.2 31.0 1.6 1 1 1 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain AbiEi_4 PF13338.6 EAX90668.1 - 0.093 12.9 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Pkinase PF00069.25 EAX90669.1 - 3.7e-64 216.6 0.0 4.5e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90669.1 - 1.2e-41 142.7 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX90669.1 - 0.00037 19.4 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX90669.1 - 0.0023 17.3 0.0 0.0044 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX90669.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1679 PF07914.11 EAX90669.1 - 0.05 12.5 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 EAX90669.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain V-ATPase_G PF03179.15 EAX90672.1 - 9.2e-08 32.6 14.9 1.1e-07 32.4 14.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EAX90672.1 - 0.0054 16.8 5.4 0.0054 16.8 5.4 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) MazG PF03819.17 EAX90672.1 - 0.034 14.3 1.9 0.32 11.2 0.1 2.4 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Ead_Ea22 PF13935.6 EAX90672.1 - 0.062 14.0 4.6 0.071 13.8 4.6 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF1870 PF08965.10 EAX90672.1 - 0.078 13.0 6.0 2.2 8.3 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) Ku_C PF03730.14 EAX90672.1 - 0.26 12.0 10.6 1.7 9.4 8.2 2.2 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm DUF883 PF05957.13 EAX90672.1 - 0.36 11.5 4.3 0.53 10.9 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 EAX90672.1 - 0.36 10.8 9.2 0.12 12.4 3.0 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) V-ATPase_G_2 PF16999.5 EAX90672.1 - 0.44 11.0 9.3 10 6.6 9.3 2.0 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF262 PF03235.14 EAX90672.1 - 0.5 10.5 6.6 0.58 10.3 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 EssA PF10661.9 EAX90672.1 - 0.53 10.1 14.5 0.48 10.3 1.3 2.2 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA FdhE PF04216.12 EAX90672.1 - 0.54 10.1 4.4 0.61 9.9 4.4 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation AAA_11 PF13086.6 EAX90672.1 - 0.6 9.8 10.6 0.65 9.7 10.6 1.0 1 0 0 1 1 1 0 AAA domain DUF4956 PF16316.5 EAX90672.1 - 0.76 9.4 2.5 0.49 10.0 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4956) RRF PF01765.19 EAX90672.1 - 0.91 9.5 15.8 0.72 9.8 14.3 1.5 1 1 1 2 2 2 0 Ribosome recycling factor DUF948 PF06103.11 EAX90672.1 - 1.6 9.1 7.6 5.9 7.2 7.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 EAX90672.1 - 2.9 7.1 9.7 3.4 6.8 9.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Zip PF02535.22 EAX90672.1 - 6.7 5.8 5.7 7.4 5.7 5.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter BTB PF00651.31 EAX90673.1 - 1.7e-12 47.5 0.3 3.5e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain Staphylokinase PF02821.16 EAX90673.1 - 0.67 10.4 3.9 5.2 7.5 3.9 2.1 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family Pkinase_Tyr PF07714.17 EAX90675.1 - 2e-05 24.0 0.1 4.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX90676.1 - 4.9e-31 108.1 0.0 5.3e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90676.1 - 5.1e-26 91.5 0.0 5.6e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase V-SNARE PF05008.15 EAX90677.1 - 0.03 14.7 0.1 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Hfx_Cass5 PF18287.1 EAX90677.1 - 0.096 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 PSP PF04046.16 EAX90678.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90679.1 - 0.29 11.9 5.8 17 6.6 0.2 3.2 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX90680.1 - 4.1e-156 517.6 12.9 5.1e-156 517.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90680.1 - 0.09 13.2 2.1 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX90680.1 - 0.36 11.4 6.3 0.25 11.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX90680.1 - 0.47 10.9 7.2 2.1 8.8 0.9 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TTL PF03133.15 EAX90681.1 - 1.4e-62 211.6 2.3 2.6e-62 210.6 2.3 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX90681.1 - 1.3e-10 40.9 0.7 4.1e-05 22.9 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX90681.1 - 1.5e-06 27.7 0.0 0.0034 16.7 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX90681.1 - 0.0031 17.6 0.0 0.063 13.3 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAX90681.1 - 0.023 14.2 0.0 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Fringe PF02434.16 EAX90682.1 - 7.8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EAX90682.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase UvrB_inter PF17757.1 EAX90682.1 - 0.072 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 UvrB interaction domain Pkinase PF00069.25 EAX90683.1 - 3.1e-23 82.5 0.0 3.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90683.1 - 4.9e-14 52.2 0.0 6.3e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3452 PF11934.8 EAX90685.1 - 0.096 12.3 0.6 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Peripla_BP_2 PF01497.18 EAX90686.1 - 0.0011 18.6 0.1 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein DUF4107 PF13389.6 EAX90687.1 - 2.1e-71 239.3 3.0 2.7e-71 239.0 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX90687.1 - 0.082 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX90688.1 - 0.0085 15.8 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX90689.1 - 3.7e-149 494.8 14.6 4.6e-149 494.5 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90689.1 - 0.025 15.0 2.7 0.067 13.6 0.4 2.1 2 0 0 2 2 2 0 Fez1 PRD PF00874.20 EAX90689.1 - 0.23 11.8 3.5 0.47 10.8 0.1 3.0 2 2 0 2 2 2 0 PRD domain KELK PF15796.5 EAX90689.1 - 0.51 10.8 7.4 1.6 9.3 0.6 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX90689.1 - 0.54 10.8 7.1 0.16 12.5 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2939 PF11159.8 EAX90690.1 - 0.025 15.0 0.5 0.031 14.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX90690.1 - 1.3 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX90690.1 - 1.4 8.9 5.5 1.5 8.8 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX90691.1 - 0.026 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX90692.1 - 0.0083 16.1 6.0 0.013 15.5 6.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4107 PF13389.6 EAX90694.1 - 2.1e-71 239.3 3.0 2.7e-71 239.0 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX90694.1 - 0.076 13.4 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX90695.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX90696.1 - 5.7e-153 507.3 12.5 7.3e-153 506.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX90696.1 - 0.044 14.0 0.4 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 NTP_transf_6 PF06042.11 EAX90696.1 - 0.09 12.6 1.4 0.32 10.9 1.4 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX90696.1 - 1.8 9.1 5.2 1.9 9.0 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase JMY PF15871.5 EAX90697.1 - 0.0051 16.2 0.4 0.0066 15.8 0.4 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAX90697.1 - 0.12 12.4 1.1 0.24 11.4 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) HTH_11 PF08279.12 EAX90697.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain T5orf172 PF10544.9 EAX90698.1 - 9.2e-07 29.4 0.6 3.1e-06 27.7 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX90698.1 - 0.089 12.6 0.6 0.51 10.2 0.2 2.4 2 1 0 2 2 2 0 KilA-N domain DUF3781 PF12636.7 EAX90699.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) APP_N PF02177.16 EAX90700.1 - 0.2 12.0 0.9 4.7 7.7 0.0 3.0 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding DUF4795 PF16043.5 EAX90700.1 - 0.34 10.5 3.6 0.58 9.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) DUF1201 PF06716.11 EAX90701.1 - 0.0066 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) Chlam_PMP PF02415.17 EAX90701.1 - 0.015 15.7 23.3 0.11 13.0 0.1 7.0 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chordopox_A13L PF05961.11 EAX90701.1 - 0.11 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Oxidored_FMN PF00724.20 EAX90702.1 - 1.8e-54 185.3 0.0 1.8e-34 119.6 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 EAX90702.1 - 1.7e-05 24.4 0.1 2.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ADIP PF11559.8 EAX90704.1 - 0.0056 16.8 12.9 0.0056 16.8 12.9 4.0 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EAX90704.1 - 0.019 15.4 4.8 0.019 15.4 4.8 6.2 1 1 5 6 6 6 0 Cell division protein ZapB GIT_CC PF16559.5 EAX90704.1 - 0.15 11.9 0.2 0.15 11.9 0.2 5.2 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 EAX90704.1 - 0.9 9.8 42.8 1.1 9.5 11.8 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EAX90704.1 - 0.96 8.7 39.8 0.01 15.2 9.1 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) COG5 PF10392.9 EAX90704.1 - 1.2 9.3 22.1 0.28 11.4 12.3 3.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 ATG16 PF08614.11 EAX90704.1 - 1.4 9.1 45.6 0.75 10.0 23.5 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAX90704.1 - 2.5 6.9 54.3 3.4 6.5 10.6 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein SlyX PF04102.12 EAX90704.1 - 2.8 8.6 26.1 0.15 12.7 5.1 4.8 3 1 2 5 5 5 0 SlyX Fez1 PF06818.15 EAX90704.1 - 8.3 6.8 47.3 0.068 13.6 22.8 2.6 1 1 1 2 2 2 0 Fez1 Ribosomal_S11 PF00411.19 EAX90705.1 - 4.5e-42 142.9 0.7 4.5e-42 142.9 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein S11 DUF3839 PF12943.7 EAX90706.1 - 2e-155 515.3 12.4 2.6e-155 515.0 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90706.1 - 0.038 14.4 1.5 0.1 13.0 0.3 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX90706.1 - 0.082 12.8 1.6 0.21 11.4 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX90706.1 - 0.46 10.8 4.0 12 6.3 0.0 3.6 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX90706.1 - 2.2 8.8 6.0 3.4 8.2 0.2 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX90707.1 - 0.04 14.4 0.5 0.094 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX90707.1 - 0.77 9.9 3.8 9.8 6.3 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX90708.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90709.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP IBD PF10416.9 EAX90710.1 - 3e-43 146.9 1.1 4.2e-43 146.4 1.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Ras PF00071.22 EAX90711.1 - 3.8e-54 182.6 0.2 4.5e-54 182.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90711.1 - 8.8e-33 113.1 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90711.1 - 5.1e-14 52.1 0.1 5.9e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX90711.1 - 3.5e-05 23.8 1.2 0.088 12.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX90711.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX90711.1 - 0.0017 18.4 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX90711.1 - 0.011 16.1 0.0 0.013 15.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EAX90711.1 - 0.019 14.5 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX90711.1 - 0.028 14.2 0.1 0.073 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EAX90711.1 - 0.043 13.2 0.0 0.065 12.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EAX90711.1 - 0.097 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 EAX90711.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Nup35_RRM_2 PF14605.6 EAX90712.1 - 1.1e-14 54.1 0.0 2.6e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EAX90712.1 - 0.0075 16.1 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EAX90712.1 - 0.058 13.4 0.2 0.26 11.3 0.2 2.1 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DNA_pol_B PF00136.21 EAX90713.1 - 4.3e-89 299.3 0.0 6.2e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAX90713.1 - 7.5e-25 87.8 1.8 3.7e-13 49.3 0.1 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EAX90713.1 - 0.00015 22.2 15.6 0.00048 20.5 15.6 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Herpes_IE2_3 PF03361.14 EAX90713.1 - 0.23 11.3 1.6 0.47 10.3 0.0 2.3 3 0 0 3 3 3 0 Herpes virus intermediate/early protein 2/3 Sedlin_N PF04628.13 EAX90714.1 - 5.8e-15 55.6 0.3 6.6e-15 55.4 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EAX90714.1 - 6.6e-05 22.9 0.3 8e-05 22.6 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family VWA_2 PF13519.6 EAX90715.1 - 4.1e-05 24.2 0.0 9.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EAX90715.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like PBECR4 PF18813.1 EAX90715.1 - 0.0094 16.2 0.4 0.014 15.6 0.4 1.3 1 0 0 1 1 1 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 Acetyltransf_7 PF13508.7 EAX90716.1 - 7e-14 52.0 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAX90716.1 - 8.4e-14 51.8 0.0 1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAX90716.1 - 9.4e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAX90716.1 - 6.6e-07 29.6 0.0 7.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAX90716.1 - 4.4e-06 26.8 0.0 5.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAX90716.1 - 0.00048 20.2 0.0 0.00085 19.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EAX90716.1 - 0.0013 18.3 0.5 0.0022 17.5 0.5 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 EAX90716.1 - 0.068 12.9 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ AAA PF00004.29 EAX90717.1 - 2.1e-18 67.0 0.1 4.2e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 EAX90717.1 - 3.1e-08 33.7 0.1 6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Hydrolase_3 PF08282.12 EAX90717.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF815 PF05673.13 EAX90717.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EAX90717.1 - 0.014 15.8 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain Molydop_binding PF01568.21 EAX90717.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain ATPase_2 PF01637.18 EAX90717.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4911 PF16256.5 EAX90719.1 - 0.053 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) HMG_box PF00505.19 EAX90721.1 - 1.6e-10 41.2 0.2 4.6e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX90721.1 - 2.7e-05 24.7 0.1 0.00019 21.9 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 EAX90721.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain Mit_proteolip PF08039.11 EAX90721.1 - 0.1 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial proteolipid Pkinase PF00069.25 EAX90722.1 - 5.8e-31 107.8 0.0 7.5e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90722.1 - 3.1e-15 56.2 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAX90722.1 - 0.046 14.4 5.7 0.17 12.6 5.7 2.1 1 1 0 1 1 1 0 Protein kinase C terminal domain Borrelia_orfA PF02414.15 EAX90722.1 - 0.099 12.3 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Borrelia ORF-A MFS_1 PF07690.16 EAX90723.1 - 1.1e-07 31.1 17.7 1.7e-07 30.5 17.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 EAX90725.1 - 1.8e-39 135.7 0.1 3e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90725.1 - 4.7e-19 68.7 0.0 6.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX90725.1 - 4.5e-09 36.7 1.5 1.2e-08 35.4 1.5 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EAX90725.1 - 0.039 14.2 0.1 0.067 13.5 0.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 EAX90725.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX90725.1 - 0.078 12.6 0.1 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 EAX90725.1 - 0.3 11.5 3.5 2.7 8.5 1.8 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4378 PF14309.6 EAX90726.1 - 0.054 13.9 0.1 0.31 11.4 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) Ras PF00071.22 EAX90728.1 - 1.8e-61 206.5 0.4 2.4e-61 206.1 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90728.1 - 3.5e-37 127.3 0.1 7.5e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90728.1 - 1.3e-14 54.1 0.1 1.8e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX90728.1 - 5.6e-06 26.0 0.3 3.7e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX90728.1 - 1.1e-05 25.5 0.1 1.8e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX90728.1 - 0.00031 21.2 0.1 0.00058 20.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX90728.1 - 0.00035 20.5 2.0 0.18 11.7 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EAX90728.1 - 0.00043 19.7 0.6 0.0021 17.5 0.6 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX90728.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EAX90728.1 - 0.0014 18.9 0.1 0.0052 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EAX90728.1 - 0.0032 17.2 0.2 0.019 14.7 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TssR PF17643.1 EAX90728.1 - 0.0046 15.0 2.2 0.0062 14.6 2.2 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssR AAA_24 PF13479.6 EAX90728.1 - 0.0053 16.5 0.3 0.0079 15.9 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAX90728.1 - 0.0098 15.4 0.1 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 EAX90728.1 - 0.01 15.5 0.7 3.7 7.1 0.2 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 EAX90728.1 - 0.018 14.4 0.1 0.048 13.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 EAX90728.1 - 0.028 14.3 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 EAX90728.1 - 0.028 13.9 0.4 0.2 11.2 0.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3873 PF12989.7 EAX90728.1 - 0.03 14.7 0.1 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Septin PF00735.18 EAX90728.1 - 0.049 12.9 0.3 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 EAX90728.1 - 0.1 13.1 1.7 0.23 12.0 1.7 1.8 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EAX90728.1 - 0.15 12.3 0.5 0.72 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EAX90728.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_2 PF12796.7 EAX90729.1 - 5.5e-16 58.9 7.8 1.7e-13 51.0 2.5 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90729.1 - 1.7e-13 50.7 1.7 7.9e-06 26.3 0.1 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90729.1 - 4.4e-11 42.0 1.5 0.00081 19.7 0.1 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX90729.1 - 5.7e-11 42.4 0.5 1.4e-06 28.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX90729.1 - 3.2e-10 40.0 0.8 0.0066 16.9 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX90730.1 - 2.9e-12 46.8 2.3 1.6e-08 34.9 0.4 3.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90730.1 - 2.5e-08 34.4 0.3 4.9e-07 30.2 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90730.1 - 6.9e-07 29.1 1.5 0.0088 16.5 0.1 4.2 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX90730.1 - 1.8e-06 28.1 0.2 4.1e-06 27.0 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX90730.1 - 5.2e-06 26.7 0.7 0.18 12.3 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat LRR_5 PF13306.6 EAX90731.1 - 1.5e-100 332.1 89.6 6e-24 84.4 3.0 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90731.1 - 1e-20 73.2 22.2 0.00014 21.5 1.0 8.3 4 2 3 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAX90731.1 - 0.063 13.7 24.8 2.9 8.4 0.5 6.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Imm58 PF15581.6 EAX90731.1 - 0.069 13.3 0.0 0.47 10.6 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 58 UCH PF00443.29 EAX90732.1 - 6.8e-26 91.3 6.3 1.4e-25 90.3 6.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX90732.1 - 5.9e-08 32.7 8.9 1.6e-06 28.0 8.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAX90732.1 - 3e-05 23.5 0.6 0.0039 16.5 0.2 2.3 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 Ank_4 PF13637.6 EAX90733.1 - 1.9e-07 31.5 0.1 0.003 18.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90733.1 - 4.4e-07 30.4 0.6 4.8e-07 30.3 0.6 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90733.1 - 1.5e-05 25.2 1.0 0.14 12.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX90733.1 - 0.0036 17.6 0.2 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90733.1 - 0.013 15.9 0.6 3.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat DUF3839 PF12943.7 EAX90734.1 - 2.1e-152 505.4 13.3 2.9e-152 505.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX90734.1 - 0.024 15.1 1.1 0.085 13.3 0.1 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX90734.1 - 1.7 9.2 7.2 1.5 9.3 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX90735.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX90736.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX90736.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Activator-TraM PF11657.8 EAX90738.1 - 0.013 15.4 0.2 0.014 15.2 0.2 1.0 1 0 0 1 1 1 0 Transcriptional activator TraM DUF3566 PF12089.8 EAX90738.1 - 0.018 15.4 0.1 0.018 15.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Coiled-coil_56 PF09813.9 EAX90738.1 - 0.026 14.6 0.1 0.026 14.6 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 m04gp34like PF12216.8 EAX90738.1 - 0.055 13.0 0.2 0.055 13.0 0.2 1.0 1 0 0 1 1 1 0 Immune evasion protein eIF3_subunit PF08597.10 EAX90739.1 - 6.6e-09 36.0 2.7 7.1e-09 35.9 2.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ATP-synt_G PF04718.15 EAX90739.1 - 0.14 13.0 0.0 0.16 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit DUF4200 PF13863.6 EAX90740.1 - 1.6e-16 60.8 30.7 1.6e-16 60.8 30.7 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 EAX90740.1 - 0.0028 16.6 44.9 0.0085 15.0 27.3 2.4 1 1 3 4 4 4 4 Spc7 kinetochore protein Acetyltransf_11 PF13720.6 EAX90740.1 - 0.0051 17.2 1.1 0.0051 17.2 1.1 3.5 1 1 3 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_MLP1_2 PF07926.12 EAX90740.1 - 0.02 14.9 7.6 0.02 14.9 7.6 4.2 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EAX90740.1 - 0.039 14.3 1.9 0.039 14.3 1.9 4.5 5 2 0 5 5 5 0 Flagella accessory protein C (FlaC) MAD PF05557.13 EAX90740.1 - 0.07 11.5 44.5 0.13 10.6 44.2 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Phage_TAC_11 PF11836.8 EAX90740.1 - 0.16 12.1 2.3 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 DUF3584 PF12128.8 EAX90740.1 - 0.71 7.3 40.4 0.88 7.0 40.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Inhibitor_I29 PF08246.12 EAX90740.1 - 1.3 9.5 5.5 0.45 11.0 0.7 2.7 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Peptidase_S66 PF02016.15 EAX90740.1 - 6.2 7.0 10.9 0.88 9.7 0.1 3.4 2 1 0 3 3 3 0 LD-carboxypeptidase N-terminal domain OmpH PF03938.14 EAX90740.1 - 6.6 7.1 50.9 26 5.1 14.5 3.4 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) SOGA PF11365.8 EAX90743.1 - 0.007 17.5 4.0 0.007 17.5 4.0 2.1 2 1 1 3 3 2 1 Protein SOGA DUF4407 PF14362.6 EAX90743.1 - 0.0079 15.6 9.0 0.0093 15.4 9.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Prefoldin PF02996.17 EAX90743.1 - 0.044 13.7 2.0 0.044 13.7 2.0 2.8 2 1 0 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.7 EAX90743.1 - 0.055 13.6 17.9 0.032 14.4 15.2 1.9 1 1 1 2 2 2 0 Tropomyosin like DUF4140 PF13600.6 EAX90743.1 - 0.38 11.2 11.1 5.3 7.6 4.1 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ING PF12998.7 EAX90743.1 - 0.42 11.2 9.5 0.37 11.4 7.7 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ZapB PF06005.12 EAX90743.1 - 0.51 10.8 22.4 0.34 11.4 6.0 3.2 1 1 2 3 3 3 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 EAX90743.1 - 0.68 9.5 8.4 0.89 9.1 8.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 EAX90743.1 - 0.68 10.5 10.2 0.18 12.4 6.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HrpB7 PF09486.10 EAX90743.1 - 0.7 10.3 8.5 2.8 8.3 1.6 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Holin_BhlA PF10960.8 EAX90743.1 - 0.91 9.5 6.9 0.17 11.9 0.8 2.5 2 0 0 2 2 2 0 BhlA holin family Fib_alpha PF08702.10 EAX90743.1 - 0.94 9.7 12.9 10 6.3 13.0 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EAX90743.1 - 1 9.4 6.0 2.6 8.1 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EAX90743.1 - 1.1 9.8 14.3 0.31 11.6 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 EAX90743.1 - 2 8.7 6.7 20 5.5 1.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PspB PF06667.12 EAX90743.1 - 2.1 8.4 6.6 4.3 7.4 0.5 2.5 2 0 0 2 2 2 0 Phage shock protein B XhlA PF10779.9 EAX90743.1 - 2.2 8.5 12.4 9 6.6 1.8 3.2 1 1 3 4 4 4 0 Haemolysin XhlA SlyX PF04102.12 EAX90743.1 - 2.3 8.9 12.4 7.7 7.2 0.6 3.1 2 2 0 2 2 2 0 SlyX TMPIT PF07851.13 EAX90743.1 - 2.5 7.2 11.7 3.9 6.6 11.4 1.6 1 1 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 EAX90743.1 - 6.3 6.1 12.7 3 7.1 10.9 1.3 1 1 0 1 1 1 0 FAM76 protein DUF2203 PF09969.9 EAX90743.1 - 9.3 7.0 14.2 4.7 7.9 5.6 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) SecY PF00344.20 EAX90744.1 - 2.4e-55 187.9 7.1 2.9e-55 187.7 7.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EAX90744.1 - 9e-11 41.4 0.1 2.9e-09 36.6 0.0 3.2 2 0 0 2 2 2 1 Plug domain of Sec61p Dzip-like_N PF13815.6 EAX90745.1 - 1.1e-11 44.7 0.7 1.1e-11 44.7 0.7 2.8 3 1 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ARS2 PF04959.13 EAX90745.1 - 0.0028 18.0 1.0 0.0028 18.0 1.0 2.2 2 1 0 2 2 2 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 EAX90745.1 - 0.017 15.9 0.3 0.086 13.7 0.3 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 EAX90745.1 - 0.048 13.2 1.3 0.086 12.4 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_9 PF16293.5 EAX90745.1 - 0.11 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) ZapB PF06005.12 EAX90745.1 - 0.13 12.7 0.3 0.13 12.7 0.3 3.6 3 1 0 3 3 2 0 Cell division protein ZapB zf-C2HC_2 PF13913.6 EAX90745.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 EAX90745.1 - 0.13 12.7 1.4 0.21 12.1 0.2 2.1 2 0 0 2 2 1 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 EAX90745.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.8 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF4709 PF15821.5 EAX90745.1 - 0.17 12.2 10.6 0.48 10.7 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4709) zf-CHCC PF10276.9 EAX90745.1 - 0.54 10.4 1.7 14 5.8 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger domain HD_2 PF12917.7 EAX90748.1 - 0.099 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF4108 PF13390.6 EAX90749.1 - 2.7e-59 199.2 9.1 3e-59 199.1 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PcfK PF14058.6 EAX90750.1 - 0.095 13.0 9.5 0.13 12.5 9.5 1.3 1 1 0 1 1 1 0 PcfK-like protein Pox_A32 PF04665.12 EAX90751.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90751.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90751.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90751.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90751.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90751.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90751.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90751.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX90751.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90751.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90751.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX90751.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX90752.1 - 7e-32 109.6 0.3 1.8e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Ribosomal_S14 PF00253.21 EAX90754.1 - 1.9e-14 53.2 5.2 2.1e-14 53.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS91 PF14319.6 EAX90754.1 - 0.034 14.2 1.0 0.037 14.1 1.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_2 PF13696.6 EAX90754.1 - 2.2 8.2 7.5 8.4 6.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF563 PF04577.14 EAX90755.1 - 1.7e-19 70.8 0.3 3.1e-19 69.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) NIF PF03031.18 EAX90756.1 - 4.5e-42 143.5 0.0 5.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IBN_N PF03810.19 EAX90757.1 - 1.5e-05 24.8 1.8 7.9e-05 22.5 0.4 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1904 PF08921.11 EAX90757.1 - 0.66 10.3 5.9 1.9 8.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1904) Rubrerythrin PF02915.17 EAX90758.1 - 6.8e-26 91.3 6.8 9.6e-21 74.6 2.9 2.0 1 1 1 2 2 2 2 Rubrerythrin Ferritin PF00210.24 EAX90758.1 - 2.5e-09 37.2 1.1 7.9e-06 25.9 0.2 2.2 2 0 0 2 2 2 2 Ferritin-like domain HypA PF01155.19 EAX90758.1 - 0.00073 19.5 0.2 0.0015 18.5 0.2 1.5 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC5 PF06221.13 EAX90758.1 - 0.0096 15.9 0.5 0.014 15.4 0.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ferritin_2 PF13668.6 EAX90758.1 - 0.011 15.9 1.4 0.018 15.2 1.4 1.3 1 1 0 1 1 1 0 Ferritin-like domain FCH PF00611.23 EAX90758.1 - 0.013 15.8 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF892 PF05974.12 EAX90758.1 - 0.013 15.5 1.2 0.062 13.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Zn-ribbon_8 PF09723.10 EAX90758.1 - 0.028 14.5 2.4 0.062 13.4 2.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3855 PF12967.7 EAX90758.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) TackOD1 PF18551.1 EAX90758.1 - 0.056 13.1 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 RNA_POL_M_15KD PF02150.16 EAX90758.1 - 0.74 9.7 3.1 0.33 10.9 0.6 1.7 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit NRDD PF13597.6 EAX90758.1 - 0.78 8.4 4.4 0.33 9.7 0.8 2.0 2 1 1 3 3 3 0 Anaerobic ribonucleoside-triphosphate reductase zinc_ribbon_10 PF10058.9 EAX90758.1 - 3.1 7.6 4.9 0.42 10.4 0.3 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4379 PF14311.6 EAX90758.1 - 4.7 7.6 7.7 11 6.5 7.0 1.9 1 1 0 1 1 1 0 Probable Zinc-ribbon domain UPF0547 PF10571.9 EAX90758.1 - 8.3 6.6 8.6 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rubrerythrin PF02915.17 EAX90759.1 - 2.4e-27 96.0 6.4 2.9e-20 73.1 1.1 2.0 1 1 1 2 2 2 2 Rubrerythrin Ferritin PF00210.24 EAX90759.1 - 2.3e-07 30.8 0.0 0.007 16.3 0.0 2.1 2 0 0 2 2 2 2 Ferritin-like domain HypA PF01155.19 EAX90759.1 - 0.00081 19.4 0.3 0.0014 18.7 0.3 1.4 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC5 PF06221.13 EAX90759.1 - 0.0086 16.0 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Zn-ribbon_8 PF09723.10 EAX90759.1 - 0.026 14.7 2.4 0.062 13.4 2.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain FCH PF00611.23 EAX90759.1 - 0.032 14.5 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF892 PF05974.12 EAX90759.1 - 0.11 12.5 1.1 4.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) RNA_POL_M_15KD PF02150.16 EAX90759.1 - 0.67 9.9 3.1 0.33 10.9 0.6 1.8 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.6 EAX90759.1 - 6.1 6.9 6.6 3.9 7.5 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Trypan_PARP PF05887.11 EAX90762.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX90763.1 - 0.026 14.5 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Parathyroid PF01279.17 EAX90764.1 - 0.075 13.7 0.1 0.18 12.4 0.1 1.7 1 1 1 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX90765.1 - 4.3e-07 29.6 2.1 4.3e-07 29.6 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90765.1 - 3.6e-05 24.0 0.1 0.00026 21.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90765.1 - 7.1e-05 22.6 0.1 0.41 10.4 0.0 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90765.1 - 0.00013 22.0 3.2 0.0003 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90765.1 - 0.00067 19.5 0.1 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90765.1 - 0.0015 18.4 0.8 0.0026 17.6 0.8 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90765.1 - 0.0062 16.2 0.6 0.039 13.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90765.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90765.1 - 0.089 13.2 0.1 0.71 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90765.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX90765.1 - 0.1 12.2 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX90765.1 - 0.29 11.4 3.4 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX90767.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ArsC PF03960.15 EAX90768.1 - 0.21 11.7 0.9 0.37 10.8 0.8 1.4 1 1 0 1 1 1 0 ArsC family Xpo1 PF08389.12 EAX90771.1 - 0.0056 16.8 0.1 0.0092 16.0 0.0 1.3 1 1 0 1 1 1 1 Exportin 1-like protein Ank_2 PF12796.7 EAX90772.1 - 9.3e-81 266.5 4.0 3.5e-19 69.2 0.0 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX90772.1 - 1.8e-47 157.7 0.0 1.3e-06 28.5 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX90772.1 - 2.3e-42 142.5 0.0 6.9e-08 32.6 0.0 7.9 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90772.1 - 2.8e-40 131.7 0.0 0.00029 21.1 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 EAX90772.1 - 5e-40 135.4 0.0 1.6e-08 34.9 0.0 6.1 4 1 3 7 7 7 7 Ankyrin repeats (many copies) DUF3083 PF11281.8 EAX90772.1 - 2.7e-06 26.9 0.1 0.012 14.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3083) L_protein_N PF15518.6 EAX90772.1 - 9.3e-05 22.2 0.0 2.7 7.9 0.0 3.8 4 0 0 4 4 4 2 L protein N-terminus MA3 PF02847.17 EAX90772.1 - 0.012 15.5 2.5 14 5.7 0.0 5.5 4 2 3 7 7 7 0 MA3 domain DUF1598 PF07643.11 EAX90772.1 - 0.029 14.6 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1598) DUF3858 PF12970.7 EAX90772.1 - 0.033 14.2 0.4 15 5.6 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3858) Tub PF01167.18 EAX90772.1 - 0.091 12.5 0.1 1.8 8.2 0.0 2.6 1 1 0 2 2 2 0 Tub family Pox_E8 PF03394.13 EAX90772.1 - 0.2 11.2 0.0 20 4.7 0.0 3.2 1 1 1 3 3 3 0 Poxvirus E8 protein DUF3447 PF11929.8 EAX90774.1 - 2.3e-06 27.4 5.0 0.00038 20.4 0.9 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90775.1 - 2.3e-35 121.0 2.8 2e-09 37.9 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90775.1 - 3.8e-34 116.6 0.5 6.5e-08 33.0 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90775.1 - 2.1e-30 104.4 3.9 8.3e-08 32.4 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90775.1 - 9.8e-26 87.0 0.1 0.011 16.1 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EAX90775.1 - 4.2e-23 80.7 0.5 0.0015 18.9 0.0 6.6 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAX90776.1 - 2.5e-15 56.6 2.8 2.5e-08 34.3 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90776.1 - 3.6e-15 56.3 0.5 4.7e-15 55.9 0.5 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90776.1 - 1.9e-10 40.0 0.5 0.0002 21.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX90776.1 - 2.6e-10 40.3 0.3 9.5e-05 22.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX90776.1 - 2.3e-09 37.3 2.6 4.7e-06 26.8 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3775 PF12616.8 EAX90776.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3775) GCK PF07802.11 EAX90778.1 - 0.026 14.9 0.0 0.15 12.5 0.0 2.3 1 1 0 1 1 1 0 GCK domain LtuB PF17455.2 EAX90778.1 - 0.54 10.9 6.0 5.1 7.8 0.4 2.6 2 0 0 2 2 2 0 Late transcription unit B NifQ PF04891.12 EAX90778.1 - 1.1 9.6 7.4 4.9 7.5 1.8 2.4 2 0 0 2 2 2 0 NifQ Ras PF00071.22 EAX90780.1 - 1.3e-36 125.7 0.0 1.6e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90780.1 - 2.1e-26 92.5 0.0 3.7e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90780.1 - 9.6e-14 51.2 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX90780.1 - 3.6e-08 33.5 1.3 0.0015 18.5 0.3 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX90780.1 - 1.2e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX90780.1 - 1.1e-05 25.0 0.3 0.00017 21.2 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 EAX90780.1 - 0.00013 22.0 0.1 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MobB PF03205.14 EAX90780.1 - 0.00048 20.0 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EAX90780.1 - 0.0038 17.0 0.5 0.15 11.9 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EAX90780.1 - 0.0042 16.5 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EAX90780.1 - 0.0057 17.1 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAX90780.1 - 0.013 15.2 0.2 0.08 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAX90780.1 - 0.033 14.1 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EAX90780.1 - 0.044 14.3 0.3 0.083 13.4 0.3 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EAX90780.1 - 0.057 13.2 0.3 0.52 10.0 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX90780.1 - 0.058 12.9 0.5 0.32 10.5 0.5 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 EAX90780.1 - 0.061 13.0 0.1 11 5.6 0.0 3.0 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.19 EAX90780.1 - 0.076 12.6 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EAX90780.1 - 0.094 13.1 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KilA-N PF04383.13 EAX90781.1 - 4.2e-14 52.3 0.2 7.3e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX90781.1 - 0.025 14.5 0.5 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin MtrG PF04210.13 EAX90781.1 - 0.16 11.8 0.4 0.5 10.3 0.2 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G TMP PF05017.14 EAX90784.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90785.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Flavodoxin_2 PF02525.17 EAX90786.1 - 3.3e-37 128.1 0.0 4.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX90786.1 - 0.0031 17.3 0.0 0.058 13.1 0.0 2.2 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Ras PF00071.22 EAX90787.1 - 2.7e-44 150.6 0.0 3.3e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90787.1 - 2.9e-25 88.8 0.0 3.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90787.1 - 2.8e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX90787.1 - 0.00048 20.2 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX90787.1 - 0.021 14.8 0.0 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EAX90787.1 - 0.024 15.0 0.0 0.034 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX90787.1 - 0.029 14.7 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4366 PF14283.6 EAX90789.1 - 0.0065 16.5 0.2 0.012 15.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Rabaptin PF03528.15 EAX90789.1 - 0.01 14.5 5.1 0.025 13.3 5.0 1.6 1 1 0 1 1 1 0 Rabaptin HsbA PF12296.8 EAX90789.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Flavodoxin_2 PF02525.17 EAX90790.1 - 1.1e-36 126.4 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX90790.1 - 0.016 14.9 0.0 0.2 11.4 0.0 2.2 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAX90791.1 - 1.1e-36 126.4 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX90791.1 - 0.016 14.9 0.0 0.2 11.4 0.0 2.2 1 1 0 1 1 1 0 NADPH-dependent FMN reductase RmlD_sub_bind PF04321.17 EAX90792.1 - 2.9e-38 131.6 0.0 4.5e-38 131.0 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EAX90792.1 - 1.2e-25 90.4 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAX90792.1 - 1.1e-16 61.2 0.9 8.8e-14 51.6 0.1 2.1 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAX90792.1 - 4.9e-11 42.3 0.3 1.7e-07 30.7 0.0 3.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EAX90792.1 - 8.2e-10 38.1 1.1 1.1e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAX90792.1 - 6.1e-07 28.9 0.3 0.0073 15.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Sigma70_r4_2 PF08281.12 EAX90792.1 - 0.031 13.9 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 ssDNA-exonuc_C PF10141.9 EAX90792.1 - 0.06 13.0 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Helicase_C PF00271.31 EAX90792.1 - 0.11 12.8 0.1 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain KR PF08659.10 EAX90792.1 - 0.15 12.0 0.2 1.2 9.0 0.2 2.1 1 1 1 2 2 2 0 KR domain ERM PF00769.19 EAX90793.1 - 3.9 7.2 56.6 0.45 10.3 18.2 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Pribosyltran_N PF13793.6 EAX90794.1 - 6.9e-14 51.8 0.0 1.8e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EAX90794.1 - 9e-08 31.8 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EAX90794.1 - 2.6e-07 30.9 0.2 3.8e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain EF-hand_7 PF13499.6 EAX90795.1 - 1.1e-20 73.8 1.0 5.5e-09 36.3 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX90795.1 - 1.8e-19 67.9 1.9 0.00042 20.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EAX90795.1 - 1.5e-18 64.9 12.0 2.4e-06 26.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EAX90795.1 - 1.3e-12 47.3 8.8 1.3e-06 28.1 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EAX90795.1 - 3.6e-12 45.2 7.0 0.0024 17.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX90795.1 - 0.00053 20.3 0.8 0.6 10.5 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 EAX90795.1 - 0.015 15.5 0.6 0.46 10.7 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EAX90795.1 - 0.075 13.3 0.1 3.7 7.9 0.0 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAX90795.1 - 0.14 12.1 0.7 1.1 9.2 0.1 2.4 2 2 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 EAX90797.1 - 4.2e-44 150.0 0.0 4.7e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90797.1 - 7.7e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90797.1 - 3.7e-08 33.0 0.0 4.2e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX90797.1 - 2.1e-05 24.0 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX90797.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S14 PF00253.21 EAX90798.1 - 1.9e-14 53.2 5.2 2.1e-14 53.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS91 PF14319.6 EAX90798.1 - 0.034 14.2 1.0 0.037 14.1 1.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_2 PF13696.6 EAX90798.1 - 2.2 8.2 7.5 8.4 6.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EAX90799.1 - 6.7e-54 183.0 0.1 8.5e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90799.1 - 3.3e-42 144.6 0.0 4.3e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Baculo_RING PF05883.11 EAX90799.1 - 4.2e-05 23.6 0.2 8.3e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain Haspin_kinase PF12330.8 EAX90799.1 - 0.00011 21.3 0.4 0.00016 20.7 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX90799.1 - 0.00013 21.4 0.0 0.23 10.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like PIP49_C PF12260.8 EAX90799.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 EAX90799.1 - 0.0016 17.3 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAX90799.1 - 0.061 12.9 0.4 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Atx10homo_assoc PF09759.9 EAX90799.1 - 0.08 13.0 0.1 0.25 11.4 0.1 1.9 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Guanylate_cyc PF00211.20 EAX90800.1 - 1.7e-45 154.9 0.1 3.5e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX90800.1 - 1.3e-12 47.9 0.6 3.1e-12 46.7 0.6 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX90800.1 - 2.6e-06 27.4 1.3 6e-06 26.2 0.1 2.2 3 0 0 3 3 3 1 PAS fold HNOBA PF07701.14 EAX90800.1 - 0.0058 16.1 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated FtsL PF04999.13 EAX90800.1 - 0.23 11.5 1.6 9.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Cell division protein FtsL DUF1289 PF06945.13 EAX90801.1 - 0.081 12.7 0.7 0.24 11.3 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) UBX PF00789.20 EAX90802.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain MBD_C PF14048.6 EAX90802.1 - 0.018 15.8 0.1 0.085 13.6 0.0 2.0 1 1 1 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 CENP-R PF06729.12 EAX90802.1 - 0.055 13.4 0.7 0.08 12.9 0.7 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Ribosomal_L34e PF01199.18 EAX90803.1 - 4.5e-32 110.2 3.2 4.5e-32 110.2 3.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e Ribosomal_L34e PF01199.18 EAX90804.1 - 4.5e-32 110.2 3.2 4.5e-32 110.2 3.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e COMM_domain PF07258.14 EAX90806.1 - 0.0031 17.6 0.1 0.0057 16.7 0.1 1.4 1 0 0 1 1 1 1 COMM domain Ribosomal_S9 PF00380.19 EAX90807.1 - 2.1e-33 115.4 0.1 2.4e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ChapFlgA_N PF17656.1 EAX90807.1 - 0.027 14.6 0.2 0.9 9.8 0.0 2.2 1 1 1 2 2 2 0 FlgA N-terminal domain DUF2482 PF10655.9 EAX90809.1 - 0.031 14.8 1.2 0.073 13.6 0.4 2.1 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) FAST_1 PF06743.15 EAX90809.1 - 0.039 13.9 2.4 58 3.7 0.0 4.0 2 1 2 4 4 4 0 FAST kinase-like protein, subdomain 1 MMS1_N PF10433.9 EAX90810.1 - 9.2e-22 77.3 5.1 9.4e-21 74.0 2.8 2.4 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAX90810.1 - 8e-08 32.0 1.4 7.6e-07 28.8 0.2 2.8 2 1 1 3 3 3 2 CPSF A subunit region SH3_3 PF08239.11 EAX90811.1 - 1.1e-22 80.0 8.9 3.1e-12 46.6 2.2 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 EAX90811.1 - 3.9e-10 39.4 1.3 2.8e-06 27.0 0.8 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_2 PF07653.17 EAX90811.1 - 0.12 12.1 1.6 0.49 10.1 0.8 2.2 2 0 0 2 2 2 0 Variant SH3 domain EF-hand_7 PF13499.6 EAX90812.1 - 3e-16 59.6 9.9 8.8e-11 42.1 1.5 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX90812.1 - 7.1e-14 50.2 13.1 0.00024 20.4 1.8 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EAX90812.1 - 2.6e-13 48.7 12.5 0.00014 21.5 1.7 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EAX90812.1 - 7e-10 38.6 11.3 5e-06 26.3 0.8 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX90812.1 - 2.2e-05 23.7 15.8 0.0035 16.8 0.6 3.9 4 0 0 4 4 4 2 EF hand EF-hand_13 PF17958.1 EAX90812.1 - 0.0037 17.0 0.3 0.086 12.7 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 EAX90812.1 - 0.0059 16.4 5.3 0.029 14.2 0.4 3.1 2 1 1 3 3 3 1 EF hand EF-hand_9 PF14658.6 EAX90812.1 - 0.014 15.7 0.3 0.029 14.7 0.1 1.6 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX90812.1 - 0.017 15.4 1.3 0.37 11.1 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EAX90812.1 - 0.068 13.5 2.5 0.37 11.2 0.4 2.7 2 1 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 EAX90812.1 - 0.084 12.8 3.7 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RST PF12174.8 EAX90812.1 - 0.097 12.6 0.1 0.38 10.7 0.0 2.1 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Lip_prot_lig_C PF10437.9 EAX90813.1 - 1.3e-07 31.5 1.3 1.4e-06 28.2 0.2 2.4 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EAX90813.1 - 6.6e-07 29.3 0.0 6.2e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Acetyltransf_1 PF00583.25 EAX90815.1 - 3.8e-18 65.8 0.0 4.4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAX90815.1 - 9.6e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX90815.1 - 3e-10 40.4 0.0 4.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAX90815.1 - 2.8e-06 27.3 0.1 7.4e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EAX90815.1 - 3.7e-05 23.8 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SLT_beta PF02258.16 EAX90815.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Shiga-like toxin beta subunit FR47 PF08445.10 EAX90815.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein GAS PF13851.6 EAX90816.1 - 1.5e-53 181.1 30.5 1.5e-53 181.1 30.5 3.8 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding DUF1493 PF07377.12 EAX90817.1 - 0.025 15.0 0.6 0.062 13.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX90817.1 - 0.14 12.2 1.8 15 5.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4116 PF13475.6 EAX90818.1 - 0.024 14.3 0.2 0.099 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX90818.1 - 1.7 8.2 10.3 0.87 9.1 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAX90819.1 - 0.078 13.4 0.5 0.15 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX90820.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90821.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX90822.1 - 2.1e-31 107.7 2.5 2.1e-31 107.7 2.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX90822.1 - 0.0016 19.0 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_7 PF13176.6 EAX90823.1 - 0.024 14.7 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX90823.1 - 0.028 14.7 0.0 0.068 13.5 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAX90823.1 - 0.036 13.9 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX90823.1 - 0.067 13.3 0.1 0.56 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Gly_rich PF12810.7 EAX90825.1 - 3.5e-31 109.0 41.8 4.3e-31 108.7 41.8 1.1 1 0 0 1 1 1 1 Glycine rich protein MFS_1 PF07690.16 EAX90826.1 - 4.2e-21 75.3 24.5 4.2e-21 75.3 24.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAX90826.1 - 3.2e-12 45.7 21.5 2.4e-11 42.8 21.5 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein Neuroparsin PF07327.11 EAX90826.1 - 0.067 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Neuroparsin COPI_assoc PF08507.10 EAX90827.1 - 0.0014 18.6 20.1 0.0018 18.4 20.1 1.1 1 0 0 1 1 1 1 COPI associated protein PSP PF04046.16 EAX90828.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90829.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat Gly-zipper_Omp PF13488.6 EAX90833.1 - 0.0045 17.0 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX90833.1 - 0.062 13.2 0.5 0.12 12.3 0.5 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX90833.1 - 0.25 10.6 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX90833.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX90833.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Rad1 PF02144.16 EAX90836.1 - 2.8e-10 39.7 0.6 7.9e-09 35.0 0.3 2.1 1 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Filament PF00038.21 EAX90837.1 - 1.8e-06 27.7 51.4 0.00033 20.3 16.9 2.3 1 1 1 2 2 2 2 Intermediate filament protein DUF1664 PF07889.12 EAX90837.1 - 2.3e-06 27.7 39.4 0.042 13.9 5.4 4.8 2 1 1 4 4 4 3 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 EAX90837.1 - 1.6e-05 24.8 24.3 1.6e-05 24.8 24.3 3.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 EAX90837.1 - 0.00013 20.9 58.4 0.0012 17.9 16.5 3.4 1 1 3 4 4 4 3 Spc7 kinetochore protein Phage_GP20 PF06810.11 EAX90837.1 - 0.00091 19.1 10.9 0.00091 19.1 10.9 5.8 1 1 5 6 6 4 1 Phage minor structural protein GP20 Myosin_tail_1 PF01576.19 EAX90837.1 - 0.0012 16.8 48.5 0.0012 16.8 48.5 1.7 2 0 0 2 2 2 1 Myosin tail Tropomyosin PF00261.20 EAX90837.1 - 0.0015 18.0 16.7 0.0015 18.0 16.7 3.6 1 1 2 3 3 3 1 Tropomyosin SOGA PF11365.8 EAX90837.1 - 0.0019 19.3 5.3 0.0019 19.3 5.3 4.8 3 1 1 4 4 2 1 Protein SOGA Occludin_ELL PF07303.13 EAX90837.1 - 0.0028 18.4 34.9 2.6 8.8 0.1 5.9 2 1 4 6 6 6 0 Occludin homology domain MscS_porin PF12795.7 EAX90837.1 - 0.0035 16.9 64.7 0.14 11.7 27.6 3.7 1 1 2 3 3 3 2 Mechanosensitive ion channel porin domain Sugarporin_N PF11471.8 EAX90837.1 - 0.0036 17.2 1.0 0.0036 17.2 1.0 5.2 7 1 1 8 8 3 1 Maltoporin periplasmic N-terminal extension ABC_tran_CTD PF16326.5 EAX90837.1 - 0.0036 17.5 6.5 0.0036 17.5 6.5 6.8 4 2 3 7 7 7 1 ABC transporter C-terminal domain AIP3 PF03915.13 EAX90837.1 - 0.0039 16.4 20.1 0.0039 16.4 20.1 2.6 1 1 1 2 2 2 1 Actin interacting protein 3 CorA PF01544.18 EAX90837.1 - 0.004 16.5 36.4 0.2 11.0 9.7 4.1 1 1 3 4 4 4 3 CorA-like Mg2+ transporter protein DHR10 PF18595.1 EAX90837.1 - 0.005 16.9 16.8 0.005 16.9 16.8 5.8 3 1 2 6 6 4 1 Designed helical repeat protein 10 domain DUF5082 PF16888.5 EAX90837.1 - 0.0091 16.3 48.0 0.38 11.0 19.2 4.2 1 1 3 4 4 4 2 Domain of unknown function (DUF5082) FAM184 PF15665.5 EAX90837.1 - 0.0095 15.7 16.8 0.0095 15.7 16.8 2.9 2 1 1 3 3 3 1 Family with sequence similarity 184, A and B EzrA PF06160.12 EAX90837.1 - 0.011 13.9 50.5 0.062 11.5 50.4 2.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA LOH1CR12 PF10158.9 EAX90837.1 - 0.019 15.0 1.4 0.019 15.0 1.4 3.9 2 1 2 4 4 3 0 Tumour suppressor protein CENP-F_leu_zip PF10473.9 EAX90837.1 - 0.023 14.7 51.8 0.22 11.5 16.4 5.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.9 EAX90837.1 - 0.037 14.0 56.0 0.3 11.0 13.6 5.2 2 1 4 6 6 6 0 Axonemal dynein light chain Baculo_PEP_C PF04513.12 EAX90837.1 - 0.039 14.0 42.3 0.98 9.5 6.2 4.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 EAX90837.1 - 0.067 12.5 55.7 0.22 10.8 25.6 4.0 1 1 3 4 4 4 0 Dynamitin HOOK PF05622.12 EAX90837.1 - 0.084 11.0 59.7 0.19 9.8 21.0 2.7 1 1 2 3 3 3 0 HOOK protein DUF3450 PF11932.8 EAX90837.1 - 0.1 11.9 53.4 0.98 8.7 14.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 EAX90837.1 - 0.14 11.7 36.6 0.64 9.5 17.1 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit GAS PF13851.6 EAX90837.1 - 0.16 11.3 57.6 0.045 13.1 16.5 4.7 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAX90837.1 - 0.2 11.7 49.2 0.44 10.6 18.2 5.4 1 1 5 6 6 6 0 Laminin Domain II Vps5 PF09325.10 EAX90837.1 - 0.2 11.2 38.5 0.038 13.5 11.3 4.5 1 1 4 5 5 5 0 Vps5 C terminal like Med9 PF07544.13 EAX90837.1 - 0.23 11.6 49.9 0.051 13.7 12.9 5.8 2 1 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 ApoO PF09769.9 EAX90837.1 - 0.3 11.0 9.7 3.8 7.5 1.0 4.5 1 1 2 3 3 3 0 Apolipoprotein O DUF883 PF05957.13 EAX90837.1 - 0.33 11.6 36.2 0.39 11.4 7.8 5.4 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) FlxA PF14282.6 EAX90837.1 - 0.4 10.7 73.2 0.16 12.0 9.9 6.8 3 1 5 8 8 6 0 FlxA-like protein Fib_alpha PF08702.10 EAX90837.1 - 0.41 10.8 49.6 0.12 12.6 11.2 4.7 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EAX90837.1 - 0.43 9.6 44.5 0.25 10.4 16.1 3.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YtxH PF12732.7 EAX90837.1 - 0.58 10.7 39.2 7.6 7.1 1.9 6.1 1 1 3 4 4 4 0 YtxH-like protein DUF2935 PF11155.8 EAX90837.1 - 0.75 10.1 16.9 1.6 9.1 3.2 4.3 1 1 3 4 4 3 0 Domain of unknown function (DUF2935) CdvA PF18822.1 EAX90837.1 - 0.76 9.6 49.2 7 6.5 0.7 7.0 4 2 3 7 7 6 0 CdvA-like coiled-coil domain Fez1 PF06818.15 EAX90837.1 - 0.78 10.2 50.0 6.5 7.1 24.4 3.4 1 1 2 3 3 2 0 Fez1 Hemerythrin PF01814.23 EAX90837.1 - 0.83 10.3 17.1 61 4.2 0.0 4.8 3 1 2 5 5 4 0 Hemerythrin HHE cation binding domain WXG100 PF06013.12 EAX90837.1 - 0.86 9.9 34.2 3.4 8.0 6.1 6.6 2 1 3 6 6 5 0 Proteins of 100 residues with WXG DUF3584 PF12128.8 EAX90837.1 - 0.9 7.0 57.7 2 5.8 19.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3287 PF11690.8 EAX90837.1 - 0.95 9.2 7.0 0.94 9.2 1.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Tmemb_cc2 PF10267.9 EAX90837.1 - 1.1 8.3 47.4 0.11 11.6 3.0 3.3 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF4200 PF13863.6 EAX90837.1 - 1.2 9.6 53.6 0.11 12.9 11.5 4.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) APG17 PF04108.12 EAX90837.1 - 1.3 8.1 39.0 0.092 11.8 12.9 3.6 1 1 2 3 3 2 0 Autophagy protein Apg17 Tektin PF03148.14 EAX90837.1 - 1.6 7.4 46.5 0.15 10.8 18.4 4.5 1 1 2 4 4 4 0 Tektin family BLOC1_2 PF10046.9 EAX90837.1 - 2 8.8 49.2 4.6 7.6 0.6 6.9 2 1 7 9 9 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 EAX90837.1 - 2.1 8.5 56.9 0.23 11.7 20.6 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) LPP PF04728.13 EAX90837.1 - 2.2 8.8 0.0 2.2 8.8 0.0 8.8 5 2 4 9 9 7 0 Lipoprotein leucine-zipper FapA PF03961.13 EAX90837.1 - 2.2 6.8 49.6 0.22 10.1 12.7 3.9 1 1 2 4 4 4 0 Flagellar Assembly Protein A DUF4407 PF14362.6 EAX90837.1 - 2.2 7.6 50.4 9.7 5.4 27.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EAX90837.1 - 2.6 8.7 47.7 5.6 7.6 5.9 5.6 1 1 3 4 4 3 0 Syntaxin 6, N-terminal FUSC PF04632.12 EAX90837.1 - 2.7 6.4 19.6 2.3 6.7 7.3 2.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family SF-assemblin PF06705.11 EAX90837.1 - 3 7.1 50.2 33 3.7 8.9 4.5 2 1 1 3 3 3 0 SF-assemblin/beta giardin HMMR_N PF15905.5 EAX90837.1 - 3 7.2 54.6 6.9 6.0 23.5 3.5 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Laminin_I PF06008.14 EAX90837.1 - 3.2 7.4 52.7 5.1 6.7 14.4 4.4 2 1 2 4 4 4 0 Laminin Domain I DUF2802 PF10975.8 EAX90837.1 - 3.7 7.7 36.6 16 5.7 1.5 8.3 4 1 2 7 7 7 0 Protein of unknown function (DUF2802) Taxilin PF09728.9 EAX90837.1 - 4.1 6.5 50.1 1.7e+02 1.1 48.0 2.8 2 1 0 2 2 2 0 Myosin-like coiled-coil protein Snapin_Pallidin PF14712.6 EAX90837.1 - 5.1 7.6 50.0 0.7 10.3 4.6 5.5 5 1 1 6 6 5 0 Snapin/Pallidin DUF724 PF05266.14 EAX90837.1 - 5.1 6.9 48.0 0.19 11.6 1.6 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 EAX90837.1 - 5.7 5.4 51.3 1.5 7.4 35.2 2.7 1 1 2 3 3 3 0 AAA domain MAD PF05557.13 EAX90837.1 - 6.4 5.0 56.2 1.4e+03 -2.7 56.2 2.5 1 1 0 1 1 1 0 Mitotic checkpoint protein Packaging_FI PF14000.6 EAX90837.1 - 6.6 7.2 44.0 2.2 8.7 1.1 6.0 1 1 5 6 6 5 0 DNA packaging protein FI DUF4618 PF15397.6 EAX90837.1 - 7.5 5.9 47.4 2.8 7.3 28.8 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) HBM PF16591.5 EAX90837.1 - 7.6 5.9 40.7 12 5.2 17.3 3.9 1 1 1 2 2 2 0 Helical bimodular sensor domain Jnk-SapK_ap_N PF09744.9 EAX90837.1 - 7.8 6.7 54.0 0.45 10.7 19.7 4.4 1 1 5 6 6 6 0 JNK_SAPK-associated protein-1 PspA_IM30 PF04012.12 EAX90837.1 - 8 6.0 47.7 41 3.7 19.9 4.5 1 1 2 3 3 3 0 PspA/IM30 family SlyX PF04102.12 EAX90837.1 - 9 7.0 52.6 2.6 8.7 3.7 7.6 4 1 4 8 8 7 0 SlyX DUF2203 PF09969.9 EAX90837.1 - 9.1 7.0 37.5 1.3 9.8 7.1 4.9 1 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2203) RPW8 PF05659.11 EAX90837.1 - 9.9 5.8 21.2 0.056 13.1 3.0 4.3 2 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3504 PF12012.8 EAX90838.1 - 0.00025 21.0 0.0 6.8 6.6 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF3504) Las1 PF04031.13 EAX90838.1 - 0.012 15.8 2.9 3.1 7.9 0.0 2.7 2 1 1 3 3 3 0 Las1-like PsaL PF02605.15 EAX90838.1 - 0.024 14.3 0.4 5.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI DUF3504 PF12012.8 EAX90839.1 - 3.8e-06 26.9 0.4 9.6 6.1 0.0 4.5 4 1 0 4 4 4 3 Domain of unknown function (DUF3504) Deltameth_res PF16020.5 EAX90839.1 - 0.037 13.9 0.0 15 5.5 0.0 3.1 2 0 0 2 2 2 0 Deltamethrin resistance PsaL PF02605.15 EAX90839.1 - 0.067 12.8 1.6 6.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Photosystem I reaction centre subunit XI Las1 PF04031.13 EAX90839.1 - 0.89 9.7 5.9 4.7 7.3 0.1 3.4 2 1 0 3 3 3 0 Las1-like DUF2057 PF09829.9 EAX90840.1 - 8.9 6.4 7.8 2.5 8.2 1.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3839 PF12943.7 EAX90841.1 - 4e-62 209.8 3.8 4.4e-62 209.7 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX90841.1 - 0.033 13.7 0.4 0.037 13.5 0.4 1.0 1 0 0 1 1 1 0 Z1 domain DUF3839 PF12943.7 EAX90842.1 - 9.6e-80 267.5 11.0 1.3e-79 267.1 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX90842.1 - 0.062 13.9 1.0 0.1 13.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LD_cluster2 PF18163.1 EAX90842.1 - 0.12 11.9 0.5 1.1 8.7 0.0 2.4 2 1 1 3 3 3 0 SLOG cluster2 ZapB PF06005.12 EAX90842.1 - 0.17 12.3 1.5 0.57 10.7 0.2 2.3 3 0 0 3 3 3 0 Cell division protein ZapB KilA-N PF04383.13 EAX90843.1 - 4e-45 152.3 1.7 4.4e-45 152.1 0.1 1.9 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX90843.1 - 0.027 14.6 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAX90845.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90845.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90845.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90845.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90845.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90845.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90845.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90845.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX90845.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90845.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90845.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX90845.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX90847.1 - 6.5e-58 194.7 8.5 7.3e-58 194.6 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX90848.1 - 1.3e-05 25.6 2.0 9e-05 22.9 2.0 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX90848.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4106 PF13388.6 EAX90849.1 - 1.6e-270 897.3 32.1 1.6e-270 897.3 32.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX90849.1 - 0.065 13.5 0.1 1.8 8.9 0.2 2.7 2 0 0 2 2 2 0 Kidney androgen-regulated SPA PF08616.10 EAX90851.1 - 0.041 13.8 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis DHHC PF01529.20 EAX90852.1 - 1.3e-18 67.4 8.0 1.3e-18 67.4 8.0 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Cpn10 PF00166.21 EAX90853.1 - 6e-21 74.3 0.1 6.7e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ANAPC4_WD40 PF12894.7 EAX90854.1 - 4.5e-07 30.1 0.2 0.029 14.7 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX90854.1 - 2.4e-05 24.3 2.8 0.033 14.1 0.5 3.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EAX90854.1 - 0.00072 20.3 0.1 5.9 7.9 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat RNA_helicase PF00910.22 EAX90854.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TraI_2B PF18340.1 EAX90854.1 - 0.081 13.0 0.1 5.5 7.1 0.0 2.3 1 1 1 2 2 2 0 DNA relaxase TraI 2B/2B-like domain PTP2 PF17022.5 EAX90855.1 - 0.048 13.3 0.3 0.076 12.6 0.3 1.2 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia PSP PF04046.16 EAX90856.1 - 0.075 12.9 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90857.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX90857.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Caskin-tail PF16632.5 EAX90858.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin PTR PF12789.7 EAX90859.1 - 0.0054 16.7 1.0 0.0054 16.7 1.0 3.7 2 1 2 4 4 3 1 Phage tail repeat like DHOR PF06537.11 EAX90860.1 - 0.18 10.4 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase DUF3839 PF12943.7 EAX90861.1 - 1.5e-157 522.3 13.5 1.9e-157 522.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX90861.1 - 0.39 11.2 7.1 2.4 8.7 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX90861.1 - 0.56 10.5 3.4 2.3 8.6 0.0 3.2 2 2 1 3 3 3 0 Rx N-terminal domain T5orf172 PF10544.9 EAX90862.1 - 0.0064 17.0 0.1 0.012 16.1 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain Orn_Arg_deC_N PF02784.16 EAX90864.1 - 2.9e-63 213.6 0.0 3.5e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EAX90864.1 - 6.8e-12 45.5 0.0 1e-11 44.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EAX90864.1 - 0.037 13.5 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel PSP PF04046.16 EAX90865.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90866.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90867.1 - 0.029 14.8 0.5 0.063 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX90868.1 - 1.9e-55 184.8 36.4 1.6e-32 111.4 20.0 5.4 5 2 1 6 6 6 2 Phage tail repeat like DUF3839 PF12943.7 EAX90869.1 - 2.1e-26 92.9 0.4 2.8e-26 92.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LRR_8 PF13855.6 EAX90870.1 - 0.076 12.8 1.0 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeat PGM_PMM_I PF02878.16 EAX90871.1 - 2.9e-40 137.2 0.1 7.9e-40 135.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EAX90871.1 - 1.1e-23 83.8 0.0 3.2e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EAX90871.1 - 8.5e-10 38.8 0.1 1.7e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EAX90871.1 - 6.4e-06 26.3 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Alpha-amylase PF00128.24 EAX90872.1 - 8e-16 58.5 0.1 5.6e-15 55.7 0.1 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain zf-CCCH_3 PF15663.5 EAX90872.1 - 0.11 12.7 0.4 0.24 11.6 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Mpt_N PF09176.11 EAX90872.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal TRP PF06011.12 EAX90874.1 - 0.00022 20.1 2.6 0.00022 20.1 2.6 1.5 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel MARVEL PF01284.23 EAX90874.1 - 3.5 7.6 10.6 0.41 10.7 3.4 2.7 2 1 1 3 3 3 0 Membrane-associating domain DUF3839 PF12943.7 EAX90876.1 - 8.5e-154 510.0 14.1 1.1e-153 509.7 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX90876.1 - 0.52 10.6 2.6 1.5 9.1 0.1 2.9 2 2 0 2 2 2 0 Rx N-terminal domain KELK PF15796.5 EAX90876.1 - 2 8.9 6.5 2 8.9 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Helicase_C PF00271.31 EAX90877.1 - 9.8e-11 42.0 0.0 2.2e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF494 PF04361.13 EAX90877.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Sec63 PF02889.16 EAX90878.1 - 2e-23 82.9 0.2 2.4e-23 82.6 0.2 1.0 1 0 0 1 1 1 1 Sec63 Brl domain Myb_DNA-binding PF00249.31 EAX90880.1 - 1.6e-25 89.0 0.8 8.3e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90880.1 - 1.3e-23 83.0 5.4 1.7e-14 53.8 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX90880.1 - 2.3e-06 27.6 2.0 0.042 13.9 0.0 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX90880.1 - 8.1e-05 22.4 4.0 0.0066 16.3 1.6 2.3 1 1 1 2 2 2 2 Myb DNA-binding like HEPN_RES_NTD1 PF18870.1 EAX90880.1 - 0.0015 18.7 1.3 0.0021 18.3 0.3 1.7 2 1 0 2 2 2 1 HEPN/RES N-terminal domain 1 Myb_DNA-bind_2 PF08914.11 EAX90880.1 - 0.0037 17.4 0.3 2.3 8.4 0.0 2.7 2 1 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 EAX90880.1 - 0.02 15.0 0.1 0.039 14.0 0.1 1.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EAX90880.1 - 0.081 13.1 2.1 0.32 11.2 2.1 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 LRR_4 PF12799.7 EAX90881.1 - 7.5e-43 143.8 84.2 3.5e-06 27.3 5.3 13.5 7 2 6 14 14 14 10 Leucine Rich repeats (2 copies) PP2C PF00481.21 EAX90881.1 - 2.8e-39 135.3 0.1 4e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAX90881.1 - 7.3e-32 108.9 64.0 2.6e-08 33.5 0.6 12.9 5 5 6 13 13 13 9 Leucine rich repeat LRR_6 PF13516.6 EAX90881.1 - 6.4e-10 38.3 55.3 0.13 12.4 0.6 15.4 16 0 0 16 16 16 6 Leucine Rich repeat PP2C_2 PF13672.6 EAX90881.1 - 2.1e-09 37.3 0.0 4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 EAX90881.1 - 1.8e-05 24.6 62.0 4 8.4 0.2 16.5 17 2 0 17 17 17 3 Leucine Rich Repeat SpoIIE PF07228.12 EAX90881.1 - 0.14 12.0 0.2 0.35 10.7 0.2 1.7 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) F5_F8_type_C PF00754.25 EAX90882.1 - 0.002 18.2 0.0 0.0045 17.1 0.0 1.6 2 0 0 2 2 2 1 F5/8 type C domain Ank_2 PF12796.7 EAX90883.1 - 7.8e-11 42.4 3.6 0.11 13.1 0.1 5.6 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90883.1 - 1.7e-07 31.7 1.2 0.17 12.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90883.1 - 7.4e-07 29.0 3.1 0.1 13.2 0.0 7.0 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 EAX90883.1 - 0.0074 16.7 0.1 9 6.9 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat GatB_Yqey PF02637.18 EAX90883.1 - 0.071 13.0 0.9 23 4.9 0.0 3.3 3 0 0 3 3 3 0 GatB domain DUF3447 PF11929.8 EAX90883.1 - 3.8 7.5 9.1 2 8.4 0.1 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) DUF1146 PF06612.11 EAX90884.1 - 0.045 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX90884.1 - 0.074 13.2 0.9 0.3 11.2 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) MULE PF10551.9 EAX90885.1 - 3e-13 50.0 2.8 3.4e-13 49.8 0.4 2.5 3 0 0 3 3 3 1 MULE transposase domain WRKY PF03106.15 EAX90885.1 - 0.065 13.5 2.2 0.16 12.3 1.0 2.3 1 1 1 2 2 2 0 WRKY DNA -binding domain DUF2362 PF10154.9 EAX90888.1 - 0.0011 18.1 2.6 0.0015 17.5 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF563 PF04577.14 EAX90891.1 - 2.5e-32 112.7 0.1 3.9e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 EAX90892.1 - 6.9e-34 117.4 0.0 3.5e-33 115.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX90892.1 - 2.8e-13 49.8 0.0 1.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAX90892.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX90892.1 - 0.014 14.7 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX90892.1 - 0.039 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family LRR_4 PF12799.7 EAX90893.1 - 2.3e-22 78.7 15.5 2.9e-08 33.8 0.4 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX90893.1 - 7.5e-19 67.9 1.3 2.9e-14 53.0 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAX90893.1 - 5.3e-14 51.7 14.3 8.1e-07 28.7 3.4 4.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EAX90893.1 - 0.00095 19.4 16.5 13 6.8 1.2 6.9 6 1 0 6 6 6 2 Leucine Rich Repeat bPH_1 PF08000.11 EAX90893.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain LRR_2 PF07723.13 EAX90893.1 - 0.52 11.1 6.3 88 4.0 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EAX90893.1 - 4.8 7.5 18.2 11 6.3 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat DUF563 PF04577.14 EAX90894.1 - 7.8e-37 127.5 0.8 1e-36 127.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DsrC PF04358.13 EAX90894.1 - 0.0044 17.5 0.0 0.028 14.9 0.0 2.2 2 0 0 2 2 2 1 DsrC like protein Reo_sigmaC_M PF17750.1 EAX90894.1 - 1.2 9.0 3.2 5.6 6.9 0.4 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein triple beta spiral Peptidase_S8 PF00082.22 EAX90895.1 - 1.2e-36 126.5 0.1 1.8e-36 125.9 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DUF2911 PF11138.8 EAX90895.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2911) DUF2326 PF10088.9 EAX90895.1 - 0.079 12.7 0.4 0.18 11.5 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) DUF563 PF04577.14 EAX90896.1 - 1e-37 130.3 0.0 1.4e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Metallophos PF00149.28 EAX90897.1 - 7.5e-33 114.8 0.1 1.1e-32 114.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX90897.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 EAX90898.1 - 1e-55 187.7 0.9 1.3e-55 187.5 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90898.1 - 1.1e-32 112.7 0.2 1.7e-32 112.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90898.1 - 1.2e-20 73.6 0.2 1.5e-20 73.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX90898.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX90898.1 - 6.7e-08 32.2 0.3 9.9e-08 31.6 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX90898.1 - 7.3e-08 32.2 0.3 4.8e-06 26.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX90898.1 - 2.4e-07 30.4 0.2 3e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX90898.1 - 1.9e-06 27.9 1.8 0.01 15.8 0.2 2.6 1 1 1 2 2 2 2 RsgA GTPase Septin PF00735.18 EAX90898.1 - 4.1e-06 26.3 0.0 6.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 EAX90898.1 - 1.1e-05 25.3 0.7 0.0011 18.8 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EAX90898.1 - 7.1e-05 22.4 0.1 0.00022 20.8 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 EAX90898.1 - 0.00042 20.5 0.0 0.00056 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX90898.1 - 0.00055 20.2 0.4 0.0015 18.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EAX90898.1 - 0.0008 19.2 0.4 0.0011 18.7 0.4 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX90898.1 - 0.0071 16.7 0.4 0.015 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAX90898.1 - 0.009 15.8 0.1 0.018 14.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX90898.1 - 0.0098 16.3 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAX90898.1 - 0.015 15.2 0.3 0.053 13.4 0.0 1.9 2 1 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EAX90898.1 - 0.019 14.9 0.2 0.031 14.2 0.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EAX90898.1 - 0.028 15.0 0.0 0.057 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX90898.1 - 0.028 14.9 0.2 0.05 14.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAX90898.1 - 0.033 14.2 0.1 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAX90898.1 - 0.046 14.0 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX90898.1 - 0.065 12.7 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EAX90898.1 - 0.081 12.5 0.2 0.081 12.5 0.2 2.5 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain T5orf172 PF10544.9 EAX90899.1 - 1.3e-07 32.1 0.3 2.6e-07 31.1 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain Guanylate_cyc PF00211.20 EAX90900.1 - 2.2e-40 138.3 0.0 4.5e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX90900.1 - 1e-13 51.4 3.3 1.1e-13 51.3 1.1 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAX90900.1 - 0.00025 21.3 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAX90900.1 - 0.0003 20.8 0.2 0.0007 19.6 0.2 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX90900.1 - 0.00075 19.0 0.2 0.0017 17.8 0.2 1.6 1 0 0 1 1 1 1 Heme NO binding associated Cation_efflux PF01545.21 EAX90901.1 - 6.5e-49 166.4 7.7 9e-49 165.9 7.7 1.2 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 EAX90901.1 - 0.41 10.5 0.1 0.41 10.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) DUF4448 PF14610.6 EAX90903.1 - 0.0029 17.4 0.0 0.0032 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4366 PF14283.6 EAX90903.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CD34_antigen PF06365.12 EAX90903.1 - 0.17 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family VPDSG-CTERM PF18205.1 EAX90903.1 - 3 7.8 5.3 0.73 9.7 0.7 2.0 2 0 0 2 2 2 0 VPDSG-CTERM motif LRR_5 PF13306.6 EAX90904.1 - 4.1e-41 139.9 22.7 6.8e-22 77.8 7.2 2.9 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90904.1 - 1.5e-05 24.7 2.4 5.2 6.9 0.0 5.1 4 2 1 5 5 5 3 Leucine rich repeat LRR_5 PF13306.6 EAX90905.1 - 3.6e-56 188.6 23.6 5.2e-33 113.7 7.8 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90905.1 - 1.3e-08 34.5 1.0 0.0042 16.8 0.0 4.1 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX90905.1 - 0.00025 21.4 3.3 2.7 8.5 0.1 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EAX90906.1 - 1.3e-42 144.2 4.7 5.6e-08 33.3 0.0 7.5 4 4 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90906.1 - 1.3e-25 86.7 1.8 0.17 12.5 0.0 12.8 13 1 1 14 14 14 6 Ankyrin repeat Ank_4 PF13637.6 EAX90906.1 - 5.1e-23 81.1 2.5 0.00032 21.2 0.1 10.1 6 4 6 12 12 12 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX90906.1 - 1.1e-20 73.4 0.0 0.011 16.0 0.0 8.8 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX90906.1 - 1.1e-13 51.0 0.0 0.14 12.7 0.1 9.4 9 1 0 9 9 9 3 Ankyrin repeat DUF3447 PF11929.8 EAX90906.1 - 0.39 10.7 25.9 0.19 11.7 1.2 6.9 6 2 1 7 7 7 0 Domain of unknown function (DUF3447) LRR_5 PF13306.6 EAX90907.1 - 2.5e-40 137.4 33.2 5.2e-31 107.3 14.3 3.3 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX90907.1 - 9.8e-08 31.6 0.4 0.0002 21.0 0.1 4.2 2 1 2 4 4 4 2 Leucine rich repeat Stevor PF17410.2 EAX90907.1 - 0.11 12.0 2.5 0.09 12.3 0.7 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Not1 PF04054.15 EAX90909.1 - 1.4e-23 83.5 8.7 1.2e-16 60.6 1.0 3.2 2 1 0 3 3 3 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAX90909.1 - 4.8e-08 32.7 0.0 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Viral_P18 PF04521.13 EAX90910.1 - 0.0078 16.0 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein Ank_2 PF12796.7 EAX90911.1 - 2.6e-84 277.9 27.0 2e-17 63.5 0.1 7.4 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90911.1 - 6.3e-82 269.0 18.7 9.5e-12 45.2 0.1 11.2 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX90911.1 - 1.2e-78 256.4 4.5 3.9e-08 33.4 0.1 10.3 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX90911.1 - 8.6e-66 217.2 17.9 4.1e-10 39.7 0.1 8.2 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90911.1 - 5.1e-65 207.7 12.3 7.5e-06 25.9 0.0 11.1 11 0 0 11 11 11 8 Ankyrin repeat DUF3447 PF11929.8 EAX90911.1 - 7.7e-38 128.3 5.9 7.7e-38 128.3 5.9 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) ThiS-like PF14453.6 EAX90911.1 - 2.3e-08 33.9 14.0 14 5.8 0.0 9.8 5 1 4 10 10 10 1 ThiS-like ubiquitin Mqo PF06039.15 EAX90911.1 - 0.011 14.3 0.3 0.77 8.2 0.1 3.3 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) DUF3012 PF11216.8 EAX90911.1 - 0.12 12.5 8.8 36 4.5 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3012) GPI-anchored PF10342.9 EAX90911.1 - 0.41 11.4 9.0 87 4.0 0.1 5.7 3 1 4 7 7 7 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Corona_S2 PF01601.16 EAX90912.1 - 0.00087 17.9 9.5 0.0011 17.6 9.5 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF3094 PF11293.8 EAX90912.1 - 0.2 11.4 1.4 0.4 10.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TLD PF07534.16 EAX90913.1 - 5e-32 111.0 1.1 8.8e-32 110.2 1.1 1.4 1 0 0 1 1 1 1 TLD LysM PF01476.20 EAX90913.1 - 6.3e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 LysM domain PTR PF12789.7 EAX90916.1 - 2.3e-08 34.0 1.0 2.3e-08 34.0 1.0 3.4 2 1 1 3 3 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX90916.1 - 0.013 15.2 0.3 0.036 13.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PTR PF12789.7 EAX90917.1 - 2.5e-05 24.2 1.5 4.1e-05 23.5 1.0 1.7 2 0 0 2 2 2 1 Phage tail repeat like AIP3 PF03915.13 EAX90917.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Tmemb_cc2 PF10267.9 EAX90917.1 - 0.15 11.2 0.4 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TMP PF05017.14 EAX90919.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90920.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP HWE_HK PF07536.14 EAX90922.1 - 0.13 13.0 0.0 0.4 11.4 0.0 1.8 1 0 0 1 1 1 0 HWE histidine kinase TIP49 PF06068.13 EAX90923.1 - 1.2e-152 508.2 1.3 1.5e-152 507.9 1.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EAX90923.1 - 2e-18 66.3 0.3 1.4e-17 63.5 0.2 2.5 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EAX90923.1 - 9e-12 45.6 2.5 1.4e-06 28.8 0.1 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAX90923.1 - 1.9e-11 44.0 0.0 2.5e-07 30.6 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAX90923.1 - 1.7e-05 25.1 0.0 0.074 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAX90923.1 - 2.3e-05 24.9 0.1 0.0077 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EAX90923.1 - 6.6e-05 22.9 0.2 0.043 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 EAX90923.1 - 0.00035 20.6 0.1 0.087 12.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EAX90923.1 - 0.00079 18.9 0.1 0.094 12.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAX90923.1 - 0.0011 18.7 0.1 1.4 8.6 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EAX90923.1 - 0.0016 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX90923.1 - 0.0029 17.9 0.6 0.12 12.7 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAX90923.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAX90923.1 - 0.018 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EAX90923.1 - 0.022 14.6 0.1 9.7 6.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAX90923.1 - 0.03 14.5 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX90923.1 - 0.045 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EAX90923.1 - 0.058 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EAX90923.1 - 0.082 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAX90923.1 - 0.093 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EAX90923.1 - 0.1 13.0 1.5 0.41 11.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain PIG-P PF08510.12 EAX90924.1 - 0.022 14.7 1.1 0.11 12.4 0.6 2.1 2 0 0 2 2 2 0 PIG-P Ribosomal_L16 PF00252.18 EAX90925.1 - 3.4e-33 114.4 0.1 4.2e-33 114.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 EAX90925.1 - 0.053 13.6 0.3 9 6.5 0.0 2.9 3 0 0 3 3 3 0 Corticotropin-releasing factor family PI3_PI4_kinase PF00454.27 EAX90926.1 - 2.6e-50 171.6 1.9 4.9e-50 170.7 0.0 2.4 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAX90926.1 - 5.5e-19 68.6 8.6 5.5e-19 68.6 8.6 2.8 2 1 1 3 3 3 1 FAT domain DUF3385 PF11865.8 EAX90926.1 - 7.4e-10 39.0 0.1 7.4e-10 39.0 0.1 5.1 2 2 1 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 EAX90926.1 - 4.6e-08 32.8 0.1 1.2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EAX90926.1 - 2.1e-05 24.8 0.0 0.026 14.9 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EAX90926.1 - 0.00012 22.0 2.1 3.3 8.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 EAX90926.1 - 0.023 14.9 0.4 0.51 10.5 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1476 PF07345.11 EAX90926.1 - 0.049 14.0 0.2 0.17 12.2 0.2 1.9 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Tox-REase-5 PF15648.6 EAX90926.1 - 0.12 12.8 1.4 0.55 10.8 0.4 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 ANAPC3 PF12895.7 EAX90926.1 - 0.34 11.2 3.3 44 4.4 0.0 3.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin PF00085.20 EAX90927.1 - 1.3e-18 66.9 0.0 1.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX90927.1 - 7.7e-07 29.4 0.1 0.00089 19.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX90927.1 - 0.00011 22.7 0.1 0.00054 20.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAX90927.1 - 0.00024 21.2 0.1 0.00044 20.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EAX90927.1 - 0.00039 19.9 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EAX90927.1 - 0.0004 20.3 0.0 0.00052 19.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EAX90927.1 - 0.00086 19.1 0.0 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EAX90927.1 - 0.0014 18.6 0.1 0.016 15.2 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family Glutaredoxin PF00462.24 EAX90927.1 - 0.0021 18.2 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EAX90927.1 - 0.0081 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.10 EAX90927.1 - 0.017 14.9 1.7 0.1 12.3 1.2 1.9 1 1 1 2 2 2 0 Redoxin DUF836 PF05768.14 EAX90927.1 - 0.059 13.8 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) CcmD PF04995.14 EAX90928.1 - 0.15 12.2 0.6 0.57 10.3 0.1 2.3 2 1 1 3 3 3 0 Heme exporter protein D (CcmD) FliJ PF02050.16 EAX90929.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein FAS_N PF17828.1 EAX90932.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX90932.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX90933.1 - 0.02 15.3 0.6 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX90933.1 - 1.8 7.6 4.4 1.9 7.4 4.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX90933.1 - 3.4 7.7 7.9 3.7 7.6 7.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX90934.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX90934.1 - 0.09 12.8 0.6 0.13 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF3839 PF12943.7 EAX90935.1 - 3e-154 511.5 13.4 3.7e-154 511.2 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX90935.1 - 0.0071 16.2 0.8 0.024 14.5 0.2 1.9 1 1 1 2 2 2 1 Nucleotidyltransferase KELK PF15796.5 EAX90935.1 - 0.24 11.8 5.4 1.8 9.1 0.6 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX90935.1 - 0.26 11.8 0.2 0.26 11.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Amidase02_C PF12123.8 EAX90937.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX90938.1 - 4e-72 241.7 2.6 5.2e-72 241.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) FliJ PF02050.16 EAX90939.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Myb_DNA-binding PF00249.31 EAX90940.1 - 1.8e-05 24.8 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90940.1 - 0.00018 21.7 0.9 0.00018 21.7 0.9 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Glyco_transf_17 PF04724.13 EAX90941.1 - 2.1e-22 79.7 0.1 2.8e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Myb_DNA-binding PF00249.31 EAX90942.1 - 4.8e-31 106.7 1.7 1.3e-16 60.5 0.4 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90942.1 - 2e-20 72.8 0.2 9.8e-12 45.0 0.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EAX90942.1 - 0.00015 21.7 0.5 0.00097 19.2 0.1 2.1 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EAX90942.1 - 0.00074 19.5 0.1 0.017 15.1 0.0 2.2 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAX90942.1 - 0.069 13.0 0.0 14 5.7 0.0 2.3 1 1 1 2 2 2 0 Myb DNA-binding like Ank_4 PF13637.6 EAX90943.1 - 6.3e-70 230.7 26.4 4.5e-15 55.8 0.1 7.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX90943.1 - 9.5e-58 190.3 19.2 1.8e-09 37.6 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_2 PF12796.7 EAX90943.1 - 4.7e-50 168.1 27.5 4.5e-15 56.0 1.6 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX90943.1 - 4.8e-44 143.3 15.5 3.2e-05 24.0 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX90943.1 - 7.2e-36 121.8 18.1 3.8e-09 36.6 0.5 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX90943.1 - 0.00086 19.5 0.0 29 5.0 0.0 5.2 1 1 5 6 6 6 0 N terminal of Calcineurin-like phosphoesterase DUF4424 PF14415.6 EAX90943.1 - 0.019 14.2 1.6 2.4 7.4 0.1 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4424) DUF5064 PF16703.5 EAX90943.1 - 0.02 15.4 1.7 0.26 11.8 0.2 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF5064) Ribosomal_S6 PF01250.17 EAX90943.1 - 0.094 13.0 6.1 23 5.3 0.1 5.1 2 2 5 7 7 7 0 Ribosomal protein S6 NifU_N PF01592.16 EAX90943.1 - 0.14 12.3 2.1 5.5 7.1 0.1 3.0 2 1 0 3 3 3 0 NifU-like N terminal domain PAZ_siRNAbind PF12212.8 EAX90943.1 - 0.27 11.1 1.8 56 3.6 0.0 4.2 1 1 4 5 5 5 0 PAZ domain DUF3718 PF12514.8 EAX90943.1 - 0.71 10.1 7.4 35 4.7 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAX90944.1 - 0.0016 19.0 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF348 PF03990.14 EAX90944.1 - 0.054 13.2 0.1 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Ank_5 PF13857.6 EAX90944.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90944.1 - 0.071 13.7 0.0 0.099 13.2 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX90946.1 - 3.1e-22 78.9 0.2 1e-16 61.3 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX90946.1 - 6e-14 52.2 0.0 4.5e-07 30.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX90946.1 - 7.3e-13 48.3 0.0 0.00023 21.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX90946.1 - 2.7e-11 42.6 0.0 0.0084 16.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX90946.1 - 4.1e-10 39.7 0.0 0.0063 16.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DAP_B PF07930.12 EAX90946.1 - 0.059 13.3 0.2 0.091 12.7 0.2 1.2 1 0 0 1 1 1 0 D-aminopeptidase, domain B DUF1664 PF07889.12 EAX90946.1 - 0.094 12.8 4.4 0.18 11.9 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2115 PF09888.9 EAX90946.1 - 0.096 13.2 4.4 0.16 12.5 4.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) TetR_C_23 PF17931.1 EAX90946.1 - 0.14 12.3 7.2 0.073 13.2 3.3 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Med23 PF11573.8 EAX90946.1 - 0.16 9.6 2.8 0.2 9.3 2.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Nas2_N PF18265.1 EAX90946.1 - 0.26 11.2 3.6 0.15 12.0 1.1 1.9 2 0 0 2 2 2 0 Nas2 N_terminal domain OmpH PF03938.14 EAX90946.1 - 1.1 9.6 11.8 1.9 8.8 11.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HECT PF00632.25 EAX90948.1 - 1.6e-09 37.7 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 EAX90949.1 - 2.1e-21 76.7 0.4 2.3e-21 76.6 0.4 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Gly_rich PF12810.7 EAX90951.1 - 4.1e-34 118.6 34.2 4.7e-34 118.4 34.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX90952.1 - 2.2e-24 86.7 22.2 2.9e-24 86.3 22.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Ras PF00071.22 EAX90953.1 - 1.1e-38 132.3 0.1 1.3e-38 132.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX90953.1 - 1.5e-28 99.4 0.3 2.1e-28 99.0 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX90953.1 - 8.7e-14 51.4 0.0 9.5e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX90953.1 - 9.3e-07 28.4 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX90953.1 - 2.7e-06 27.4 0.0 0.036 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX90953.1 - 7.6e-06 26.0 0.1 1.1e-05 25.5 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX90953.1 - 2.5e-05 23.9 0.0 0.00017 21.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX90953.1 - 0.00017 21.0 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EAX90953.1 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 EAX90953.1 - 0.017 14.4 0.3 0.051 12.9 0.2 1.7 1 1 1 2 2 2 0 AIG1 family AAA_16 PF13191.6 EAX90953.1 - 0.025 15.0 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EAX90953.1 - 0.038 14.3 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX90953.1 - 0.041 13.4 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAX90953.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAX90953.1 - 0.15 11.8 1.4 4.6 6.9 0.6 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Myb_DNA-binding PF00249.31 EAX90954.1 - 2.1e-10 40.6 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX90954.1 - 3.4e-08 33.6 0.1 1.1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX90954.1 - 0.022 14.6 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 Myb DNA-binding like DUF4428 PF14471.6 EAX90954.1 - 0.044 13.7 1.1 0.15 12.0 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ZZ PF00569.17 EAX90954.1 - 0.29 11.0 3.6 0.16 11.8 1.3 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type FlxA PF14282.6 EAX90955.1 - 1.6e-06 28.0 5.9 1.8e-06 27.8 5.9 1.0 1 0 0 1 1 1 1 FlxA-like protein Phage_GP20 PF06810.11 EAX90955.1 - 1.5e-05 24.9 3.7 1.7e-05 24.7 3.7 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Lebercilin PF15619.6 EAX90955.1 - 0.00094 18.9 2.4 0.0013 18.5 2.4 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 EAX90955.1 - 0.0012 18.5 3.1 0.0015 18.2 3.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein FliT PF05400.13 EAX90955.1 - 0.0072 17.1 2.2 0.01 16.6 2.2 1.3 1 0 0 1 1 1 1 Flagellar protein FliT Prefoldin PF02996.17 EAX90955.1 - 0.017 15.0 2.5 2.9 7.8 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF5339 PF17274.2 EAX90955.1 - 0.024 15.5 6.9 0.75 10.7 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Sec2p PF06428.11 EAX90955.1 - 0.034 14.1 4.6 0.6 10.1 0.2 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 EAX90955.1 - 0.054 13.9 2.6 1.5 9.3 2.6 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) LPP PF04728.13 EAX90955.1 - 0.071 13.5 2.2 4.5 7.8 2.2 2.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper TMPIT PF07851.13 EAX90955.1 - 0.085 12.1 1.5 0.098 11.9 1.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF2730 PF10805.8 EAX90955.1 - 0.093 12.8 0.9 0.13 12.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MetOD2 PF18548.1 EAX90955.1 - 0.11 12.6 4.6 0.37 10.9 2.6 2.0 1 1 1 2 2 2 0 Metanogen output domain 2 FemAB PF02388.16 EAX90955.1 - 0.12 11.2 3.6 0.14 11.0 3.6 1.0 1 0 0 1 1 1 0 FemAB family Csm1_N PF18504.1 EAX90955.1 - 0.14 12.5 5.0 3.8 7.9 0.1 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain Prefoldin_2 PF01920.20 EAX90955.1 - 0.21 11.5 5.9 1.8 8.5 2.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit SlyX PF04102.12 EAX90955.1 - 0.23 12.1 3.7 2.6 8.7 3.7 2.1 1 1 0 1 1 1 0 SlyX DUF16 PF01519.16 EAX90955.1 - 0.29 11.6 4.6 1.1 9.8 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF5320 PF17253.2 EAX90955.1 - 0.43 11.7 2.8 12 7.1 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 EAX90955.1 - 0.49 10.2 6.1 2.7 7.8 2.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Adeno_E1B_19K PF01691.16 EAX90956.1 - 0.0046 16.5 2.0 13 5.4 0.0 3.0 1 1 2 3 3 3 3 Adenovirus E1B 19K protein / small t-antigen DUF2201 PF09967.9 EAX90956.1 - 0.017 15.3 0.1 6.4 6.9 0.0 2.2 1 1 1 2 2 2 0 VWA-like domain (DUF2201) Caleosin PF05042.13 EAX90956.1 - 0.022 14.7 0.0 5.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Caleosin related protein PhnI PF05861.12 EAX90956.1 - 0.032 13.1 0.1 5.9 5.6 0.0 2.4 1 1 2 3 3 3 0 Bacterial phosphonate metabolism protein (PhnI) Longin PF13774.6 EAX90956.1 - 0.49 10.5 3.2 46 4.2 0.1 3.0 1 1 2 3 3 3 0 Regulated-SNARE-like domain FAS_N PF17828.1 EAX90958.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX90959.1 - 0.017 15.5 0.6 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX90959.1 - 1.1 8.2 2.6 1.2 8.1 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX90959.1 - 1.4 8.9 5.5 1.6 8.8 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Gly-zipper_Omp PF13488.6 EAX90961.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX90961.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX90961.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ank PF00023.30 EAX90962.1 - 2e-24 84.9 0.2 7e-09 35.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX90962.1 - 1.1e-23 83.2 0.1 6e-12 45.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX90962.1 - 1.4e-21 76.9 0.7 1.1e-20 73.9 0.3 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX90962.1 - 2.9e-21 75.2 0.1 6.2e-12 45.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX90962.1 - 5.5e-20 69.3 0.8 2.1e-06 27.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Internalin_N PF12354.8 EAX90962.1 - 0.05 13.7 0.0 44 4.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal ubiquitin PF00240.23 EAX90965.1 - 1.1e-16 60.3 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX90965.1 - 3.7e-10 39.5 0.0 4.5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX90965.1 - 0.00018 21.4 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAX90965.1 - 0.00047 20.6 0.0 0.00058 20.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX90965.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like USP7_ICP0_bdg PF12436.8 EAX90965.1 - 0.095 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Baculo_PEP_C PF04513.12 EAX90966.1 - 7.5e-06 26.0 45.4 0.086 12.9 3.1 6.0 1 1 4 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EAX90966.1 - 3.5e-05 23.8 44.7 0.021 14.7 17.8 3.7 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain Prominin PF05478.11 EAX90966.1 - 0.0043 15.1 44.6 0.14 10.1 6.9 3.1 1 1 2 3 3 3 3 Prominin IFT57 PF10498.9 EAX90966.1 - 0.0055 15.7 7.4 0.0055 15.7 7.4 5.4 2 1 3 5 5 5 1 Intra-flagellar transport protein 57 DUF1664 PF07889.12 EAX90966.1 - 0.11 12.5 49.3 0.028 14.5 3.5 6.1 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EAX90966.1 - 2.9 5.3 73.1 0.013 13.1 39.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF2959 PF11172.8 EAX90966.1 - 5 7.2 33.7 0.43 10.7 2.2 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF2959) APG17 PF04108.12 EAX90966.1 - 8.7 5.3 53.1 1.2 8.1 37.4 3.7 1 1 3 4 4 4 0 Autophagy protein Apg17 Plasmod_dom_1 PF09715.10 EAX90967.1 - 0.0044 17.0 1.1 0.0044 17.0 1.1 3.3 4 0 0 4 4 4 1 Plasmodium protein of unknown function (Plasmod_dom_1) ubiquitin PF00240.23 EAX90968.1 - 2.1e-14 53.0 0.0 2.5e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX90968.1 - 2.6e-09 36.8 0.0 3.2e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX90968.1 - 0.0004 20.2 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAX90968.1 - 0.003 18.0 0.0 0.0035 17.8 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 EAX90968.1 - 0.011 16.4 0.0 0.02 15.6 0.0 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.6 EAX90968.1 - 0.078 13.1 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 EAX90969.1 - 0.0045 17.2 1.3 0.013 15.7 0.0 2.3 2 1 0 2 2 2 1 UBX domain PP2C_C PF07830.13 EAX90969.1 - 0.027 14.9 6.2 0.39 11.2 0.9 2.9 2 2 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Carot_N PF09150.10 EAX90969.1 - 0.053 13.4 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal UIM PF02809.20 EAX90969.1 - 0.97 9.5 7.5 4.3 7.5 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif ASH PF15780.5 EAX90972.1 - 7.8e-32 109.4 44.0 0.00036 20.7 0.4 17.7 18 1 0 18 18 18 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EAX90972.1 - 2.9e-20 72.1 39.9 5.9e-05 22.9 0.9 13.4 12 1 1 13 13 13 7 MSP (Major sperm protein) domain DUF1573 PF07610.11 EAX90972.1 - 1.2e-11 44.4 33.1 0.0019 18.2 0.2 11.7 13 0 0 13 13 13 4 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EAX90972.1 - 2.9e-07 30.7 37.2 0.0017 18.6 1.0 10.6 11 1 1 12 12 12 3 Transmembrane protein 131-like Cupredoxin_1 PF13473.6 EAX90972.1 - 2.9 8.1 7.1 13 6.0 0.0 5.6 6 0 0 6 6 6 0 Cupredoxin-like domain Amidase_5 PF05382.13 EAX90973.1 - 0.18 11.7 5.5 5 7.0 1.7 2.2 1 1 1 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF4108 PF13390.6 EAX90975.1 - 9.2e-64 213.7 5.8 1e-63 213.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX90976.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX90977.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90977.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90977.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90977.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90977.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90977.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90977.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90977.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX90977.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90977.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90977.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX90977.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX90978.1 - 4.7e-34 116.6 0.5 1.2e-33 115.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain FPN1 PF06963.12 EAX90978.1 - 0.25 9.9 0.1 0.33 9.5 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) KilA-N PF04383.13 EAX90979.1 - 6.9e-42 141.8 1.0 8.1e-42 141.6 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX90979.1 - 0.0038 17.4 0.1 0.0082 16.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) RRP36 PF06102.12 EAX90979.1 - 0.01 15.8 2.4 0.025 14.5 2.4 1.6 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Cep57_MT_bd PF06657.13 EAX90979.1 - 0.039 14.4 3.4 0.33 11.4 2.9 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FPN1 PF06963.12 EAX90979.1 - 0.077 11.5 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) MPS2 PF17060.5 EAX90979.1 - 0.13 11.5 5.6 2.3 7.4 3.0 2.0 1 1 0 2 2 2 0 Monopolar spindle protein 2 Kinesin PF00225.23 EAX90980.1 - 8.3e-79 264.9 0.1 8.3e-79 264.9 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAX90980.1 - 3.5e-23 82.2 2.7 6.9e-23 81.2 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding Flt3_lig PF02947.14 EAX90980.1 - 0.043 14.0 3.7 0.066 13.4 0.8 2.7 4 0 0 4 4 4 0 flt3 ligand ssDNA_TraI_N PF18272.1 EAX90980.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain DUF812 PF05667.11 EAX90980.1 - 0.16 10.8 26.8 0.49 9.2 26.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SF3a60_bindingd PF12108.8 EAX90980.1 - 0.62 10.0 3.5 16 5.5 0.2 2.5 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Baculo_PEP_C PF04513.12 EAX90980.1 - 0.76 9.8 5.8 8.2 6.5 0.4 3.0 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAAL_N PF05034.13 EAX90980.1 - 0.99 9.0 4.9 1.1 8.9 0.3 2.3 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus KxDL PF10241.9 EAX90980.1 - 2.6 8.4 23.3 0.58 10.5 7.0 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein Spc7 PF08317.11 EAX90980.1 - 2.7 6.8 29.3 0.38 9.6 18.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 EAX90980.1 - 5.2 7.1 14.2 2.5 8.1 7.7 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Gly_rich PF12810.7 EAX90981.1 - 2.4e-54 184.8 38.8 3.1e-54 184.5 38.8 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF4108 PF13390.6 EAX90982.1 - 1.1e-55 187.4 7.6 1.3e-55 187.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX90982.1 - 0.095 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PcfK PF14058.6 EAX90983.1 - 0.08 13.2 10.4 0.11 12.8 10.4 1.3 1 1 0 1 1 1 0 PcfK-like protein Pox_A32 PF04665.12 EAX90984.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX90984.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX90984.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX90984.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX90984.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX90984.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX90984.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX90984.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX90984.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX90984.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX90984.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX90984.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX90985.1 - 3.7e-157 521.0 11.5 4.6e-157 520.7 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX90985.1 - 0.083 13.2 1.4 9.2 6.7 0.1 3.5 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX90985.1 - 0.13 12.7 4.7 2.1 8.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAX90988.1 - 0.013 15.5 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX90988.1 - 0.084 13.5 5.7 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX90989.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP 7TMR-DISM_7TM PF07695.11 EAX90990.1 - 0.0022 17.9 1.5 0.0024 17.8 1.5 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF2207 PF09972.9 EAX90990.1 - 0.055 12.2 0.1 0.056 12.2 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OSTbeta PF15048.6 EAX90990.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SLATT_5 PF18160.1 EAX90990.1 - 0.13 11.5 2.2 0.17 11.2 2.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TAFH PF07531.14 EAX90991.1 - 0.055 13.6 1.6 21 5.3 0.0 4.0 3 0 0 3 3 3 0 NHR1 homology to TAF RNA_pol_Rpb2_45 PF10385.9 EAX90992.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit external 1 domain Head_binding PF09008.10 EAX90992.1 - 0.03 14.6 0.8 0.25 11.6 0.1 2.5 2 0 0 2 2 2 0 Head binding AbfS_sensor PF18225.1 EAX90992.1 - 0.11 12.5 0.0 0.94 9.4 0.1 2.1 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain GET2 PF08690.10 EAX90993.1 - 0.37 10.4 4.2 6.3 6.4 0.2 2.5 1 1 1 2 2 2 0 GET complex subunit GET2 ChiC PF06483.11 EAX90993.1 - 4.4 7.2 12.8 2.3 8.1 0.7 4.1 1 1 3 5 5 5 0 Chitinase C Ntox24 PF15529.6 EAX90993.1 - 9.8 6.6 8.6 41 4.6 0.4 3.8 4 0 0 4 4 4 0 Bacterial toxin 24 MG2 PF01835.19 EAX90994.1 - 0.0051 17.2 0.9 48 4.5 0.0 6.1 6 1 0 6 6 6 1 MG2 domain TcfC PF16967.5 EAX90994.1 - 0.053 13.0 0.1 0.17 11.4 0.1 1.9 1 0 0 1 1 1 0 E-set like domain Epiglycanin_TR PF05647.11 EAX90995.1 - 1.2 9.1 43.3 0.032 14.2 22.8 3.1 2 1 1 3 3 3 0 Tandem-repeating region of mucin, epiglycanin-like DndE PF08870.11 EAX90996.1 - 4.5e-06 26.9 0.1 15 5.9 0.0 5.0 1 1 5 6 6 6 3 DNA sulphur modification protein DndE Porin_4 PF13609.6 EAX90996.1 - 6.6e-06 26.1 0.0 0.0017 18.1 0.0 2.7 1 1 0 1 1 1 1 Gram-negative porin Glyco_hydro_65C PF03633.15 EAX90996.1 - 0.00026 20.8 11.0 53 3.8 0.1 7.7 7 0 0 7 7 7 0 Glycosyl hydrolase family 65, C-terminal domain DUF1823 PF08853.11 EAX90996.1 - 0.02 15.1 0.3 1.3e+02 2.8 0.0 4.3 3 1 1 5 5 5 0 Domain of unknown function (DUF1823) DUF3499 PF12005.8 EAX90996.1 - 0.039 14.6 0.5 3.1e+02 2.0 0.0 5.0 1 1 5 6 6 6 0 Protein of unknown function (DUF3499) ShlB PF03865.13 EAX90996.1 - 0.1 12.1 0.8 9.9 5.5 0.1 3.1 2 1 2 4 4 4 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB DUF3674 PF12426.8 EAX90996.1 - 1.1 9.4 5.5 94 3.2 0.0 4.3 6 0 0 6 6 6 0 RNA dependent RNA polymerase PSP PF04046.16 EAX90997.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX90998.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX90999.1 - 0.028 14.9 0.8 0.061 13.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX91000.1 - 4.2e-31 106.8 9.6 4.2e-31 106.8 9.6 3.3 4 0 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAX91000.1 - 0.077 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX91000.1 - 4.5 7.2 7.9 1.9 8.4 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF240) DUF3839 PF12943.7 EAX91001.1 - 9.3e-158 523.0 12.0 1.2e-157 522.7 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91001.1 - 0.34 11.4 7.2 2.6 8.6 0.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX91001.1 - 0.89 9.9 5.4 12 6.3 0.1 3.8 4 1 1 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX91002.1 - 3.1e-06 27.7 0.2 7.3e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX91002.1 - 0.011 15.6 1.6 0.055 13.3 0.6 2.4 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX91002.1 - 0.047 13.2 0.4 0.33 10.4 0.2 1.9 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX91003.1 - 1.5e-40 137.6 0.1 2.5e-40 136.8 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAX91003.1 - 0.0036 17.9 0.0 0.007 17.0 0.0 1.4 1 0 0 1 1 1 1 Parathyroid hormone family LOH1CR12 PF10158.9 EAX91003.1 - 0.28 11.2 2.6 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Fib_alpha PF08702.10 EAX91004.1 - 0.0024 18.1 29.0 0.1 12.8 16.3 2.5 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 EAX91004.1 - 0.016 15.8 34.4 0.067 13.8 4.4 3.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 EAX91004.1 - 0.57 10.6 33.6 0.17 12.3 26.2 2.3 1 1 1 2 2 2 0 Fez1 ParD_antitoxin PF03693.14 EAX91004.1 - 0.96 9.9 3.7 0.47 10.9 0.3 2.2 2 1 1 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH AAA_13 PF13166.6 EAX91004.1 - 2.2 6.8 28.5 2.6 6.6 28.5 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EAX91004.1 - 2.6 8.1 37.4 0.37 10.9 11.6 3.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EAX91004.1 - 2.6 7.3 40.1 0.61 9.4 19.1 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LRRFIP PF09738.9 EAX91004.1 - 4.1 6.8 30.3 1.4 8.3 12.2 2.3 1 1 1 2 2 2 0 LRRFIP family FPP PF05911.11 EAX91004.1 - 6.4 4.8 34.3 23 3.0 34.3 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 EAX91004.1 - 6.5 6.0 24.0 2 7.7 14.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 EAX91004.1 - 6.9 7.0 14.7 3.9 7.8 6.2 3.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lectin_N PF03954.14 EAX91004.1 - 7.9 6.2 19.2 0.57 9.9 3.4 2.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 EAX91004.1 - 9.1 5.1 37.3 1.8 7.3 14.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EAX91005.1 - 8.2e-06 26.0 46.1 0.0075 16.5 4.4 3.7 1 1 3 4 4 4 3 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EAX91005.1 - 6.7e-05 23.2 41.8 0.003 17.8 26.6 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAX91005.1 - 0.002 17.0 22.8 0.002 17.0 22.8 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Filament PF00038.21 EAX91005.1 - 0.0025 17.4 45.2 0.076 12.6 13.4 3.2 1 1 2 3 3 3 2 Intermediate filament protein DivIC PF04977.15 EAX91005.1 - 0.0027 17.5 44.5 0.51 10.1 3.3 5.6 1 1 5 6 6 6 4 Septum formation initiator MAD PF05557.13 EAX91005.1 - 0.0027 16.1 47.5 0.0036 15.7 47.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein BicD PF09730.9 EAX91005.1 - 0.0028 16.2 20.3 0.0028 16.2 20.3 2.1 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D Atg14 PF10186.9 EAX91005.1 - 0.0032 16.6 46.8 0.0097 15.0 16.1 3.0 1 1 2 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 EAX91005.1 - 0.0037 17.8 6.1 0.0037 17.8 6.1 2.6 1 1 2 3 3 3 1 Fez1 LPP PF04728.13 EAX91005.1 - 0.0039 17.6 22.2 0.11 12.9 1.0 5.1 3 1 0 3 3 3 2 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 EAX91005.1 - 0.0067 16.5 49.4 0.13 12.3 22.6 3.6 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 EAX91005.1 - 0.019 14.1 47.6 0.2 10.7 34.7 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region ADIP PF11559.8 EAX91005.1 - 0.027 14.6 13.8 0.027 14.6 13.8 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 EAX91005.1 - 0.032 14.6 44.4 0.17 12.1 17.7 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 EAX91005.1 - 0.033 13.7 51.1 0.095 12.2 20.9 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EAX91005.1 - 0.047 13.8 53.1 0.45 10.6 7.2 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 EAX91005.1 - 0.052 14.0 4.2 0.052 14.0 4.2 5.2 1 1 4 5 5 4 0 Cell division protein ZapB Cep57_MT_bd PF06657.13 EAX91005.1 - 0.054 13.9 0.9 0.054 13.9 0.9 4.7 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 KASH_CCD PF14662.6 EAX91005.1 - 0.12 12.2 55.7 0.61 9.9 3.5 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Plant_NMP1 PF06694.11 EAX91005.1 - 0.15 11.1 15.7 0.034 13.3 2.8 2.5 1 1 1 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) GAS PF13851.6 EAX91005.1 - 0.18 11.1 53.4 0.066 12.6 13.2 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.11 EAX91005.1 - 0.21 10.9 48.6 0.23 10.8 10.7 3.7 1 1 3 4 4 4 0 Rabaptin-like protein DUF4200 PF13863.6 EAX91005.1 - 0.3 11.5 54.2 0.13 12.6 3.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) MbeD_MobD PF04899.12 EAX91005.1 - 0.35 11.0 0.2 0.35 11.0 0.2 4.4 2 1 3 5 5 5 0 MbeD/MobD like CENP-F_leu_zip PF10473.9 EAX91005.1 - 0.36 10.9 53.4 0.09 12.8 16.2 3.2 1 1 2 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EAX91005.1 - 0.75 9.9 29.4 2.5 8.2 4.5 4.5 1 1 2 3 3 3 0 TolA binding protein trimerisation Spc29 PF17082.5 EAX91005.1 - 0.84 9.4 32.5 0.53 10.1 11.2 2.9 1 1 2 3 3 3 0 Spindle Pole Component 29 APG6_N PF17675.1 EAX91005.1 - 0.86 10.1 51.6 0.37 11.3 23.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region YvrJ PF12841.7 EAX91005.1 - 0.96 9.0 3.9 11 5.6 0.2 3.3 2 0 0 2 2 2 0 YvrJ protein family YabA PF06156.13 EAX91005.1 - 1.1 9.9 42.5 0.95 10.1 6.8 3.9 1 1 3 4 4 4 0 Initiation control protein YabA Csm1_N PF18504.1 EAX91005.1 - 1.1 9.6 48.6 0.42 11.0 6.1 5.7 1 1 5 6 6 6 0 Csm1 N-terminal domain DUF848 PF05852.11 EAX91005.1 - 1.3 9.1 31.0 3.8 7.6 6.3 3.3 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2203 PF09969.9 EAX91005.1 - 2.2 9.0 30.4 0.059 14.1 6.0 4.0 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF5082 PF16888.5 EAX91005.1 - 2.4 8.5 43.5 0.25 11.6 7.4 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Cep57_CLD_2 PF14197.6 EAX91005.1 - 2.8 8.1 39.5 0.042 13.9 4.3 5.1 1 1 6 7 7 7 0 Centrosome localisation domain of PPC89 DUF724 PF05266.14 EAX91005.1 - 2.9 7.7 46.3 0.33 10.8 5.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 EAX91005.1 - 3.3 5.1 41.2 12 3.3 41.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 EAX91005.1 - 3.8 7.3 45.6 0.66 9.8 17.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1515 PF07439.11 EAX91005.1 - 3.9 7.5 18.3 4.6 7.3 0.4 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1515) Macoilin PF09726.9 EAX91005.1 - 4.8 5.6 45.6 11 4.5 12.2 2.4 1 1 1 2 2 2 0 Macoilin family DUF4140 PF13600.6 EAX91005.1 - 4.9 7.6 26.3 0.14 12.6 1.4 4.2 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF4618 PF15397.6 EAX91005.1 - 5.4 6.4 44.0 0.52 9.7 8.6 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) WEMBL PF05701.11 EAX91005.1 - 6.2 5.4 42.9 14 4.2 42.9 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Mod_r PF07200.13 EAX91005.1 - 6.4 6.9 53.2 0.73 9.9 15.6 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Yuri_gagarin PF15934.5 EAX91005.1 - 7.4 6.3 41.0 0.53 10.1 18.8 2.9 1 1 2 3 3 3 0 Yuri gagarin AAA_13 PF13166.6 EAX91005.1 - 7.8 5.0 43.8 0.97 8.0 21.6 2.0 1 1 1 2 2 2 0 AAA domain CALCOCO1 PF07888.11 EAX91005.1 - 8.2 5.2 43.7 19 4.0 43.6 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 EAX91005.1 - 9.1 5.5 44.3 6.4 6.0 6.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Dopey_N PF04118.14 EAX91007.1 - 0.0047 16.1 0.0 2.3 7.3 0.0 2.1 1 1 1 2 2 2 2 Dopey, N-terminal Vwaint PF14624.6 EAX91007.1 - 0.0096 16.0 0.1 4.8 7.4 0.0 2.2 1 1 1 2 2 2 2 VWA / Hh protein intein-like Cu_bind_CorA PF18252.1 EAX91007.1 - 0.045 13.4 0.0 8.2 6.0 0.0 2.7 1 1 2 3 3 3 0 Copper(I)-binding protein CorA DUF1661 PF07877.11 EAX91007.1 - 0.19 11.5 6.5 25 4.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) Cyclotide PF03784.13 EAX91007.1 - 0.37 10.9 6.1 6.6 6.9 0.6 2.2 2 0 0 2 2 2 0 Cyclotide family ATG27 PF09451.10 EAX91008.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Hydrolase_4 PF12146.8 EAX91009.1 - 9.1e-15 54.6 0.0 5.4e-11 42.2 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EAX91009.1 - 4.5e-10 39.6 0.0 9.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EAX91009.1 - 2.6e-06 27.3 0.3 7.6e-06 25.7 0.1 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAX91009.1 - 6.8e-06 26.8 0.0 8.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAX91009.1 - 0.0043 16.5 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EAX91009.1 - 0.0065 15.2 0.0 1.9 7.1 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 EAX91009.1 - 0.019 14.5 0.1 1.1 8.7 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 EAX91009.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EAX91009.1 - 0.055 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 EAX91009.1 - 0.066 12.5 0.1 0.5 9.6 0.1 2.0 1 1 1 2 2 2 0 Secretory lipase Esterase PF00756.20 EAX91009.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 EAX91009.1 - 0.11 10.9 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lebercilin PF15619.6 EAX91010.1 - 2.7e-05 23.9 23.4 2.7e-05 23.9 23.4 9.5 4 2 5 10 10 10 2 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EAX91010.1 - 0.0027 17.1 12.7 0.0027 17.1 12.7 11.2 4 2 6 11 11 11 5 Growth-arrest specific micro-tubule binding Caskin-tail PF16632.5 EAX91010.1 - 0.085 13.3 0.1 0.085 13.3 0.1 6.2 5 2 2 7 7 7 0 C-terminal region of Caskin CPG4 PF15481.6 EAX91010.1 - 0.64 10.7 5.5 30 5.3 0.2 4.4 2 1 1 3 3 3 0 Chondroitin proteoglycan 4 KicB PF03882.14 EAX91011.1 - 0.0068 16.6 0.1 0.03 14.5 0.0 1.9 2 0 0 2 2 2 1 MukF winged-helix domain DUF5336 PF17270.2 EAX91011.1 - 0.077 12.6 1.5 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) ArfGap PF01412.18 EAX91012.1 - 1.1e-41 141.6 0.0 1.1e-41 141.6 0.0 3.1 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Sedlin_N PF04628.13 EAX91013.1 - 4.8e-07 30.0 0.3 6.2e-07 29.6 0.3 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EAX91013.1 - 0.0032 17.4 0.1 0.0039 17.1 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family HSP70 PF00012.20 EAX91014.1 - 3.1e-93 313.0 7.3 3.1e-93 313.0 7.3 3.6 3 2 0 3 3 3 1 Hsp70 protein DUF3504 PF12012.8 EAX91016.1 - 3.4e-05 23.8 0.3 43 4.0 0.0 5.3 5 0 0 5 5 5 4 Domain of unknown function (DUF3504) UPF0139 PF03669.13 EAX91016.1 - 0.0038 17.1 6.6 15 5.5 0.1 5.2 4 0 0 4 4 4 3 Uncharacterised protein family (UPF0139) DUF563 PF04577.14 EAX91018.1 - 9.1e-37 127.2 1.1 1.2e-36 126.9 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) BING4CT PF08149.11 EAX91018.1 - 0.019 14.8 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 0 BING4CT (NUC141) domain DUF5118 PF17162.4 EAX91018.1 - 0.023 14.5 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5118) HP1451_C PF18472.1 EAX91021.1 - 0.0011 18.8 0.3 0.026 14.5 0.0 2.9 3 0 0 3 3 3 1 HP1451 C-terminal domain Bacillus_HBL PF05791.11 EAX91021.1 - 0.015 15.1 0.2 0.015 15.1 0.2 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PAH PF02671.21 EAX91021.1 - 0.29 11.3 2.4 6.2 7.0 0.5 3.9 3 1 0 3 3 3 0 Paired amphipathic helix repeat PWI PF01480.17 EAX91021.1 - 2.8 8.3 6.1 27 5.1 0.1 3.9 3 1 1 4 4 4 0 PWI domain FERM_N_2 PF18038.1 EAX91022.1 - 0.027 15.3 0.1 0.081 13.8 0.1 1.7 1 1 1 2 2 2 0 FERM N-terminal domain Meiosis_expr PF15163.6 EAX91023.1 - 0.031 14.9 1.5 0.038 14.7 0.5 1.7 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX91023.1 - 4.6 7.2 12.6 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family Myb_DNA-binding PF00249.31 EAX91025.1 - 1.2e-22 79.8 0.1 3e-14 52.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91025.1 - 2.8e-19 69.1 1.6 2.3e-10 40.5 1.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX91025.1 - 2.8e-05 23.9 0.5 6e-05 22.9 0.5 1.6 1 1 0 1 1 1 1 Myb DNA-binding like DUF4518 PF15008.6 EAX91025.1 - 0.0028 16.9 0.8 0.0033 16.7 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Cas9_PI2 PF18070.1 EAX91025.1 - 0.12 13.2 1.9 0.24 12.2 1.9 1.6 1 1 0 1 1 1 0 CRISPR-Cas9 PI domain SLIDE PF09111.10 EAX91025.1 - 0.14 12.2 1.8 0.41 10.7 0.0 2.2 1 1 1 2 2 2 0 SLIDE Nucleo_P87 PF07267.11 EAX91026.1 - 6.9 5.4 6.9 8.7 5.1 6.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 C2 PF00168.30 EAX91027.1 - 1.2e-14 54.4 0.1 1.9e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 C2 domain Guanylate_cyc PF00211.20 EAX91028.1 - 1.5e-43 148.5 0.2 6.1e-43 146.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX91028.1 - 6.2e-10 39.3 0.5 1.8e-09 37.8 0.5 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX91028.1 - 0.0095 15.9 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX91028.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 EAX91028.1 - 0.021 14.2 1.1 0.027 13.9 0.1 1.7 2 0 0 2 2 2 0 Heme NO binding associated Gly_rich PF12810.7 EAX91029.1 - 1.1e-34 120.4 29.2 1.3e-34 120.2 29.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91030.1 - 1.2e-55 189.1 43.5 1.5e-55 188.8 43.5 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91031.1 - 1.7e-56 191.9 41.1 2.3e-56 191.4 41.1 1.2 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91032.1 - 2.6e-54 184.7 42.2 3.7e-54 184.2 42.2 1.2 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91033.1 - 3e-55 187.8 41.2 4.3e-55 187.3 41.2 1.2 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91034.1 - 3e-55 187.8 41.2 4.3e-55 187.3 41.2 1.2 1 0 0 1 1 1 1 Glycine rich protein HTH_7 PF02796.15 EAX91035.1 - 0.00042 20.3 0.6 0.00077 19.5 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EAX91035.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EAX91035.1 - 0.0032 17.5 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Phage_AlpA PF05930.12 EAX91035.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Ribosomal_L10 PF00466.20 EAX91036.1 - 2.2e-20 72.7 0.3 6.1e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EAX91036.1 - 1.5e-19 69.8 0.2 2.6e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EAX91036.1 - 3.1e-09 37.3 12.3 5.6e-09 36.5 12.3 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Acyltransferase PF01553.21 EAX91037.1 - 0.0037 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L13 PF00572.18 EAX91038.1 - 5.5e-11 42.8 3.5 2e-09 37.8 0.6 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 EAX91039.1 - 4.8e-12 45.8 0.0 5.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91039.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX91039.1 - 3.6e-07 29.7 0.1 1.5e-06 27.7 0.0 1.8 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX91039.1 - 4.1e-06 26.5 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAX91039.1 - 3.3e-05 23.9 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 EAX91039.1 - 0.00022 20.9 0.0 0.00027 20.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.20 EAX91039.1 - 0.0063 15.9 0.2 0.013 14.9 0.2 1.5 1 1 1 2 2 2 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 EAX91039.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4255 PF14065.6 EAX91039.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) DUF4108 PF13390.6 EAX91040.1 - 1.9e-58 196.5 7.2 2.1e-58 196.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PTR PF12789.7 EAX91041.1 - 1.5e-53 178.7 36.7 7.4e-35 118.8 16.2 3.9 3 1 1 4 4 4 2 Phage tail repeat like Apolipoprotein PF01442.18 EAX91041.1 - 0.15 11.9 0.6 0.21 11.4 0.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1493 PF07377.12 EAX91042.1 - 0.018 15.5 0.7 0.034 14.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91043.1 - 0.11 13.2 6.2 9.5 7.4 0.2 3.3 3 1 1 4 4 4 0 TMP repeat PSP PF04046.16 EAX91044.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TPR_2 PF07719.17 EAX91045.1 - 4.9e-14 51.2 22.2 0.021 14.9 0.2 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAX91045.1 - 5.9e-14 51.2 2.0 0.07 13.0 0.3 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAX91045.1 - 1.7e-13 49.6 7.9 0.68 10.3 0.0 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX91045.1 - 8.1e-12 45.2 5.4 2.6e-05 24.3 0.0 4.0 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAX91045.1 - 1.7e-10 41.1 16.7 0.0028 17.9 0.7 7.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX91045.1 - 2e-10 41.0 3.9 0.0024 18.3 0.3 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX91045.1 - 6.7e-09 36.3 10.4 0.00097 19.7 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAX91045.1 - 9.1e-07 28.8 1.1 0.78 10.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX91045.1 - 6.9e-06 25.5 3.1 0.042 13.0 1.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX91045.1 - 0.00036 21.1 11.8 0.83 10.6 0.0 6.2 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAX91045.1 - 0.00074 19.2 3.6 6.7 6.5 0.1 4.6 4 2 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 EAX91045.1 - 0.02 14.9 3.4 60 4.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAX91045.1 - 0.45 10.5 0.0 0.45 10.5 0.0 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAX91045.1 - 9 7.2 7.9 1.2e+02 3.6 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FWWh PF14922.6 EAX91046.1 - 0.015 15.2 0.2 0.051 13.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function Na_sulph_symp PF00939.19 EAX91047.1 - 7.5e-26 91.2 29.6 1e-25 90.8 29.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAX91047.1 - 4.5e-15 55.6 44.1 8.9e-15 54.7 39.1 2.5 1 1 2 3 3 3 2 Citrate transporter Flavodoxin_1 PF00258.25 EAX91048.1 - 4.4e-22 78.8 0.0 5e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EAX91048.1 - 0.0023 18.2 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Terminase_6 PF03237.15 EAX91048.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family Rtf2 PF04641.12 EAX91049.1 - 0.022 14.1 1.3 0.025 13.9 1.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Med30 PF11315.8 EAX91049.1 - 0.045 14.0 0.3 0.067 13.4 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF1943 PF09172.11 EAX91049.1 - 0.1 11.8 1.2 0.11 11.7 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) GMP_PDE_delta PF05351.11 EAX91050.1 - 2.1e-33 115.6 0.0 2.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit DUF1120 PF06551.12 EAX91050.1 - 0.0027 17.8 0.0 0.0058 16.8 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1120) CBM_5_12_2 PF14600.6 EAX91050.1 - 0.093 12.7 0.5 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Cellulose-binding domain ATP-grasp_2 PF08442.10 EAX91051.1 - 1.3e-75 253.5 0.8 1.8e-75 253.0 0.8 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EAX91051.1 - 1.5e-26 93.0 0.8 3.3e-26 92.0 0.8 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EAX91051.1 - 0.0003 20.3 0.4 0.00082 18.9 0.4 1.8 1 1 0 1 1 1 1 ATP-grasp domain GNVR PF13807.6 EAX91051.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase CPSase_L_D2 PF02786.17 EAX91051.1 - 0.069 12.6 0.4 0.22 11.0 0.4 1.9 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ank_4 PF13637.6 EAX91053.1 - 3.1e-32 110.5 6.4 6.4e-11 42.6 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX91053.1 - 3.4e-30 103.1 5.6 6.8e-10 38.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX91053.1 - 4.2e-24 82.0 3.2 3e-07 30.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAX91053.1 - 3.2e-23 82.1 2.6 6e-14 52.4 0.4 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91053.1 - 3.4e-23 81.4 6.1 6.7e-09 35.8 0.4 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX91053.1 - 0.0043 16.8 1.0 0.66 9.7 0.1 2.1 2 0 0 2 2 2 2 Shigella flexneri OspC protein HECT PF00632.25 EAX91054.1 - 5.9e-44 150.8 0.5 5.9e-44 150.8 0.5 2.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3781 PF12636.7 EAX91055.1 - 0.025 14.4 0.8 0.039 13.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX91056.1 - 0.039 14.4 1.5 0.05 14.1 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX91057.1 - 0.055 13.4 12.9 0.057 13.4 12.9 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91057.1 - 7.2 7.1 7.8 8.4 6.8 7.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2939 PF11159.8 EAX91058.1 - 0.022 15.1 0.3 0.027 14.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX91059.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX91062.1 - 4.3e-07 29.6 0.1 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Poxvirus A32 protein DUF3781 PF12636.7 EAX91063.1 - 0.083 12.8 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX91064.1 - 2.9e-155 514.8 13.2 3.7e-155 514.5 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX91064.1 - 1.1 10.0 0.1 1.1 10.0 0.1 3.2 2 2 2 4 4 4 0 Family of unknown function (DUF5398) KELK PF15796.5 EAX91064.1 - 5.1 7.6 8.8 2 8.9 1.0 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5007 PF16398.5 EAX91065.1 - 0.11 12.2 0.1 0.13 11.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) GPS2_interact PF15784.5 EAX91069.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91069.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Myb_DNA-binding PF00249.31 EAX91070.1 - 6.3e-30 103.1 3.7 2.5e-14 53.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91070.1 - 2.2e-23 82.2 2.1 1e-15 57.7 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91070.1 - 0.00011 22.2 0.1 0.0036 17.3 0.0 2.5 3 0 0 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91070.1 - 0.0094 15.8 0.3 0.044 13.7 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like LRR_5 PF13306.6 EAX91071.1 - 7.6e-16 58.2 3.9 9.1e-16 58.0 3.9 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) E2F_TDP PF02319.20 EAX91072.1 - 1.6e-13 50.5 0.7 1.1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HSP70 PF00012.20 EAX91073.1 - 1.6e-62 211.5 9.5 1.6e-62 211.5 9.5 2.0 2 1 0 2 2 2 1 Hsp70 protein FGGY_C PF02782.16 EAX91073.1 - 0.21 11.3 0.0 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BTB PF00651.31 EAX91074.1 - 3.2e-13 49.9 0.2 2.6e-11 43.7 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain Bromodomain PF00439.25 EAX91075.1 - 3.3e-21 75.2 0.0 7.2e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DpnII PF04556.12 EAX91075.1 - 0.091 12.1 1.1 0.7 9.2 0.1 2.2 1 1 0 2 2 2 0 DpnII restriction endonuclease Nsp1_C PF05064.13 EAX91076.1 - 2.2e-12 46.8 7.8 2.2e-12 46.8 7.8 2.5 1 1 2 3 3 3 1 Nsp1-like C-terminal region DHR10 PF18595.1 EAX91076.1 - 0.0011 19.0 7.0 0.0011 19.0 7.0 2.4 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain DUF5320 PF17253.2 EAX91076.1 - 0.06 14.4 10.1 0.11 13.6 0.4 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5320) Sec34 PF04136.15 EAX91076.1 - 0.064 13.1 16.5 0.022 14.6 7.3 2.9 1 1 2 3 3 3 0 Sec34-like family Laminin_II PF06009.12 EAX91076.1 - 0.13 12.3 12.9 0.53 10.3 1.3 2.1 1 1 1 2 2 2 0 Laminin Domain II MCPsignal PF00015.21 EAX91076.1 - 0.16 11.7 6.9 0.13 12.0 1.6 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA2 PF16740.5 EAX91076.1 - 0.18 11.6 14.0 0.095 12.5 7.8 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 EAX91076.1 - 0.34 11.3 10.2 1.7 9.0 1.5 3.1 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 EAX91076.1 - 0.38 11.5 10.4 6.6 7.5 3.6 2.6 1 1 1 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 EAX91076.1 - 0.86 9.6 13.0 0.88 9.6 1.3 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX91076.1 - 0.91 9.7 14.8 0.53 10.5 5.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Goodbye PF17109.5 EAX91076.1 - 1.4 9.3 6.7 6.9 7.1 0.3 2.5 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain NFACT-C PF11923.8 EAX91076.1 - 1.5 8.7 5.9 1.4 8.9 2.8 2.3 2 1 0 2 2 2 0 NFACT protein C-terminal domain DUF745 PF05335.13 EAX91076.1 - 1.7 8.4 16.1 0.74 9.5 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 EAX91076.1 - 2.9 7.4 13.7 5.8 6.4 13.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Nbl1_Borealin_N PF10444.9 EAX91076.1 - 3 7.5 9.0 0.36 10.5 0.3 3.4 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal DUF1664 PF07889.12 EAX91076.1 - 3.1 7.8 13.5 7 6.7 4.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GHMP_kinases_C PF08544.13 EAX91076.1 - 4 7.9 4.5 8.3 6.9 1.4 2.7 1 1 1 2 2 2 0 GHMP kinases C terminal APG6_N PF17675.1 EAX91076.1 - 5 7.6 20.3 4.2 7.9 1.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DASH_Dad2 PF08654.10 EAX91076.1 - 6.5 7.2 12.2 2.7 8.5 0.4 3.0 1 1 2 3 3 3 0 DASH complex subunit Dad2 Phasin_2 PF09361.10 EAX91076.1 - 9.6 6.5 10.5 2.2 8.6 0.7 2.9 3 1 0 3 3 3 0 Phasin protein Ras PF00071.22 EAX91077.1 - 1.2e-41 142.0 0.2 1.5e-41 141.7 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91077.1 - 3.1e-30 104.9 0.0 5.4e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91077.1 - 8.3e-16 57.9 0.0 1.2e-15 57.4 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX91077.1 - 1.2e-09 38.3 0.3 0.00014 21.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX91077.1 - 3.3e-06 27.2 0.2 6.2e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX91077.1 - 0.00042 19.8 0.0 0.0006 19.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX91077.1 - 0.0016 17.9 0.1 0.0024 17.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX91077.1 - 0.078 12.7 0.3 0.24 11.1 0.3 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX91077.1 - 0.12 12.8 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAX91077.1 - 0.12 12.3 0.1 0.35 10.8 0.1 1.6 2 0 0 2 2 2 0 NACHT domain YtkA PF13115.6 EAX91077.1 - 0.25 12.0 2.8 3.5 8.3 0.0 2.8 2 1 0 2 2 2 0 YtkA-like PSP PF04046.16 EAX91078.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91079.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX91080.1 - 2.6e-146 485.5 15.0 3.2e-146 485.2 15.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX91080.1 - 0.012 16.1 1.6 0.043 14.3 0.2 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX91080.1 - 0.036 14.3 2.4 1.2 9.5 0.1 3.6 3 1 1 4 4 4 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX91080.1 - 0.11 12.4 1.2 0.32 10.8 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX91080.1 - 0.37 11.3 6.2 1.8 9.1 0.9 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX91081.1 - 1.5e-154 512.4 14.8 1.9e-154 512.1 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91081.1 - 1.1 9.7 7.3 2 8.9 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX91081.1 - 1.9 8.9 4.5 1.5 9.1 1.2 2.5 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Amidase02_C PF12123.8 EAX91083.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91084.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX91084.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase PSP PF04046.16 EAX91086.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP SPA PF08616.10 EAX91087.1 - 1.5e-07 31.3 0.1 5.1e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis DUF4407 PF14362.6 EAX91088.1 - 0.0015 18.0 12.7 0.0015 18.0 12.7 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4407) DUF2114 PF09887.9 EAX91088.1 - 0.14 10.6 5.3 0.64 8.4 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2114) AAA_13 PF13166.6 EAX91088.1 - 0.42 9.2 38.6 4.4 5.8 21.3 2.0 1 1 1 2 2 2 0 AAA domain Mto2_bdg PF12808.7 EAX91088.1 - 0.75 10.1 8.4 0.21 11.9 1.5 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF948 PF06103.11 EAX91088.1 - 6.5 7.1 12.4 1.1 9.5 2.4 3.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Phage_int_SAM_5 PF13102.6 EAX91089.1 - 0.29 11.5 4.4 0.52 10.7 0.2 3.2 4 0 0 4 4 4 0 Phage integrase SAM-like domain UNC45-central PF11701.8 EAX91089.1 - 0.5 10.3 3.2 0.38 10.7 0.5 2.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central CholecysA-Rec_N PF09193.10 EAX91090.1 - 0.072 13.1 0.1 13 5.9 0.0 2.6 1 1 1 2 2 2 0 Cholecystokinin A receptor, N-terminal DUF4107 PF13389.6 EAX91092.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX91094.1 - 6.4e-153 507.1 12.7 8.2e-153 506.8 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX91094.1 - 0.13 12.2 1.1 0.45 10.4 1.2 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAX91094.1 - 1.7 9.0 4.6 8.7 6.7 0.0 3.4 2 2 2 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX91094.1 - 5.1 7.6 7.9 1.8 9.1 0.8 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX91095.1 - 2.8e-72 242.2 4.7 3.5e-72 241.9 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX91096.1 - 1.6e-49 165.8 30.1 8e-31 105.9 14.6 4.5 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX91096.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX91097.1 - 0.056 13.9 0.5 0.13 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91098.1 - 0.33 11.7 7.2 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX91098.1 - 5.9 6.9 8.4 6.3 6.8 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDE_Tnp_ISL3 PF01610.17 EAX91099.1 - 3.2e-05 23.8 0.9 3.8e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 Transposase Adeno_E1B_55K PF01696.17 EAX91099.1 - 0.034 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen zf-C2H2_assoc2 PF16624.5 EAX91100.1 - 0.016 16.2 3.3 0.02 15.9 3.1 1.3 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger SLC12 PF03522.15 EAX91100.1 - 0.016 14.2 0.4 0.019 14.0 0.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NEMP PF10225.9 EAX91100.1 - 0.67 9.6 1.5 0.76 9.4 1.5 1.1 1 0 0 1 1 1 0 NEMP family Rota_Capsid_VP6 PF00980.17 EAX91101.1 - 0.01 14.8 0.4 0.023 13.6 0.1 1.7 2 0 0 2 2 2 0 Rotavirus major capsid protein VP6 COQ9 PF08511.11 EAX91101.1 - 0.11 12.3 0.1 0.9 9.4 0.0 2.5 3 0 0 3 3 3 0 COQ9 Prp18 PF02840.15 EAX91101.1 - 0.15 12.1 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 Prp18 domain Peptidase_S6 PF02395.16 EAX91103.1 - 0.095 10.7 0.1 0.11 10.5 0.1 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease LRR_5 PF13306.6 EAX91104.1 - 4.8e-40 136.5 49.9 5.6e-17 61.9 13.8 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91104.1 - 0.00026 20.7 7.8 4.9 7.0 0.1 5.3 5 0 0 5 5 5 2 Leucine rich repeat DUF5432 PF17497.2 EAX91104.1 - 0.032 14.3 2.5 0.082 13.0 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5432) Soyouz_module PF14313.6 EAX91106.1 - 0.19 11.5 2.6 0.62 9.9 0.0 3.3 5 0 0 5 5 5 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Ank_2 PF12796.7 EAX91107.1 - 1.7e-40 137.4 19.3 6.4e-14 52.3 1.5 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX91107.1 - 4.5e-37 125.9 6.7 4.5e-37 125.9 6.7 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX91107.1 - 4.1e-35 119.7 11.8 9.9e-08 32.4 0.1 8.0 7 1 2 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX91107.1 - 3.6e-29 99.9 8.0 1.1e-06 28.9 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX91107.1 - 7.5e-29 99.4 5.9 1.4e-09 38.0 0.0 6.5 3 3 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91107.1 - 3.7e-27 91.4 12.6 0.00075 19.8 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat PH_8 PF15409.6 EAX91107.1 - 0.019 15.2 1.0 8.5 6.7 0.1 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3718 PF12514.8 EAX91107.1 - 0.09 12.9 1.3 50 4.2 0.0 5.1 6 1 1 7 7 7 0 Protein of unknown function (DUF3718) DUF4108 PF13390.6 EAX91108.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX91109.1 - 0.0057 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX91109.1 - 0.25 10.5 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX91109.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX91109.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX91111.1 - 4.9e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX91111.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX91111.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 TMP PF05017.14 EAX91113.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91114.1 - 0.078 12.9 0.8 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 PSP AAA PF00004.29 EAX91115.1 - 4e-09 37.0 0.0 8.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAX91115.1 - 1.8e-05 25.3 0.0 5.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAX91115.1 - 2.2e-05 24.5 0.3 9e-05 22.5 0.1 2.2 2 1 0 2 2 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EAX91115.1 - 0.00031 20.5 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAX91115.1 - 0.00089 19.7 0.0 0.0032 17.9 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.27 EAX91115.1 - 0.00094 19.7 0.0 0.004 17.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter DNA_pol3_delta PF06144.13 EAX91115.1 - 0.001 18.8 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 EAX91115.1 - 0.0018 18.4 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EAX91115.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.6 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EAX91115.1 - 0.0045 17.0 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAX91115.1 - 0.0049 16.4 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EAX91115.1 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EAX91115.1 - 0.0081 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EAX91115.1 - 0.0093 15.8 1.3 0.55 10.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 EAX91115.1 - 0.01 16.2 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EAX91115.1 - 0.01 16.3 4.9 0.021 15.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain dNK PF01712.19 EAX91115.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 EAX91115.1 - 0.011 16.1 0.0 0.045 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAX91115.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX91115.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAX91115.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EAX91115.1 - 0.017 14.9 0.2 0.065 13.0 0.0 2.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EAX91115.1 - 0.018 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAX91115.1 - 0.02 14.5 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.11 EAX91115.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E T2SSE PF00437.20 EAX91115.1 - 0.04 13.0 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein API5 PF05918.11 EAX91115.1 - 0.042 12.7 0.1 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) AAA_30 PF13604.6 EAX91115.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAX91115.1 - 0.063 13.0 0.3 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 EAX91115.1 - 0.069 12.9 0.2 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAX91115.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 EAX91115.1 - 0.086 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain NACHT PF05729.12 EAX91115.1 - 0.096 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EAX91115.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EAX91116.1 - 3.9e-41 139.5 2.7 9.1e-14 51.8 0.4 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91116.1 - 2.3e-37 125.8 3.2 8.9e-06 25.9 0.1 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX91116.1 - 5.3e-37 125.7 1.2 8.4e-10 39.0 0.0 6.5 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91116.1 - 1.5e-34 114.1 0.6 4.1e-05 23.7 0.0 8.7 8 0 0 8 8 8 7 Ankyrin repeat DUF3447 PF11929.8 EAX91116.1 - 1.5e-30 104.9 6.2 1.5e-30 104.9 6.2 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX91116.1 - 7.3e-24 83.5 1.7 1.3e-07 31.8 0.1 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) DrrA_P4M PF14860.6 EAX91116.1 - 0.092 12.6 1.0 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain WD40 PF00400.32 EAX91117.1 - 8.1e-29 99.3 35.8 0.001 19.9 0.0 11.8 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX91117.1 - 9.9e-08 32.2 3.2 1.4 9.3 0.0 6.5 4 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX91117.1 - 1.1e-06 28.3 0.1 0.5 9.6 0.0 4.0 2 2 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 EAX91117.1 - 2.3e-05 24.1 0.0 0.023 14.3 0.0 3.3 2 1 1 3 3 3 2 PQQ-like domain SGL PF08450.12 EAX91117.1 - 0.0026 17.4 1.6 4.5 6.8 0.0 4.2 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Nucleoporin_N PF08801.11 EAX91117.1 - 0.11 11.2 0.7 60 2.2 0.1 3.7 4 0 0 4 4 4 0 Nup133 N terminal like UBD PF16455.5 EAX91117.1 - 0.14 12.4 0.1 0.5 10.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-binding domain LRR_9 PF14580.6 EAX91118.1 - 2.6e-15 56.4 2.8 4.3e-12 45.9 0.4 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EAX91118.1 - 2.1e-14 53.4 20.7 3.5e-08 33.6 1.0 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX91118.1 - 3e-07 30.1 6.6 0.00012 21.8 1.0 2.9 2 2 0 2 2 2 2 Leucine rich repeat DUF3744 PF12558.8 EAX91118.1 - 0.052 14.3 4.7 2 9.2 1.3 3.3 3 1 0 3 3 3 0 ATP-binding cassette cobalt transporter BAG PF02179.16 EAX91118.1 - 0.06 13.8 0.2 0.13 12.7 0.2 1.5 1 1 0 1 1 1 0 BAG domain LRR_1 PF00560.33 EAX91118.1 - 1.3 9.9 4.2 3.4 8.6 0.1 3.3 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EAX91118.1 - 2.2 8.6 6.3 23 5.4 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Cytochrom_D1 PF02239.16 EAX91119.1 - 0.0008 18.0 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EAX91119.1 - 0.0033 17.7 0.0 0.043 14.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX91119.1 - 0.13 13.2 4.6 4.4 8.3 0.0 3.5 3 1 0 3 3 3 0 WD domain, G-beta repeat Ank_2 PF12796.7 EAX91120.1 - 1.5e-07 31.9 0.1 0.00059 20.4 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91120.1 - 0.00021 21.4 0.0 4.8 8.1 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX91120.1 - 0.0019 18.8 0.1 3.4 8.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91120.1 - 0.007 16.3 6.4 0.071 13.1 6.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3447) SurA_N PF09312.11 EAX91120.1 - 0.069 13.2 0.2 0.21 11.7 0.2 1.7 1 1 0 1 1 1 0 SurA N-terminal domain Ank PF00023.30 EAX91120.1 - 0.15 12.6 0.1 36 5.1 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 EAX91120.1 - 0.15 12.4 0.0 20 5.6 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DNA_pol3_delta PF06144.13 EAX91121.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EAX91121.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain KH_1 PF00013.29 EAX91121.1 - 2.2 8.2 4.4 11 6.0 0.1 3.2 3 0 0 3 3 3 0 KH domain PSP PF04046.16 EAX91122.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91123.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX91124.1 - 0.016 15.7 0.4 0.028 14.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX91125.1 - 8.4e-39 131.5 27.0 4e-21 74.8 10.4 4.4 5 1 1 6 6 6 2 Phage tail repeat like Poxvirus_B22R_C PF13168.6 EAX91125.1 - 0.021 14.3 0.1 0.056 12.9 0.1 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF4116 PF13475.6 EAX91125.1 - 0.13 12.0 0.7 0.54 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX91125.1 - 6.6 6.3 15.5 0.17 11.5 2.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) KilA-N PF04383.13 EAX91126.1 - 2.9e-11 43.2 0.0 5.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX91127.1 - 5e-06 27.0 0.2 1.3e-05 25.7 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX91127.1 - 0.052 13.4 0.2 0.58 10.0 0.1 2.6 2 1 0 2 2 2 0 KilA-N domain KilA-N PF04383.13 EAX91128.1 - 8.9e-23 80.3 0.8 2e-22 79.1 0.0 2.0 2 1 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAX91129.1 - 3.8e-08 33.1 1.1 4.6e-08 32.8 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX91129.1 - 0.003 17.2 0.1 0.0033 17.1 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX91129.1 - 0.045 13.5 0.1 0.099 12.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX91129.1 - 0.09 12.7 0.3 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MULE PF10551.9 EAX91130.1 - 0.00016 22.0 0.1 0.00016 22.0 0.1 2.7 4 0 0 4 4 4 1 MULE transposase domain DUF2960 PF11173.8 EAX91130.1 - 0.074 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Transposase_mut PF00872.18 EAX91130.1 - 0.1 11.4 2.2 0.32 9.8 2.2 1.8 1 1 0 1 1 1 0 Transposase, Mutator family Cys_Met_Meta_PP PF01053.20 EAX91132.1 - 5e-162 538.8 0.0 5.7e-162 538.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAX91132.1 - 5.5e-10 38.7 0.2 5.8e-09 35.4 0.2 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EAX91132.1 - 7.4e-10 37.9 0.1 1.5e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EAX91132.1 - 5.6e-06 25.8 0.1 1.2e-05 24.7 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EAX91132.1 - 0.00048 19.1 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.17 EAX91132.1 - 0.031 13.6 0.1 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3158 PF11358.8 EAX91133.1 - 0.018 14.8 1.6 0.2 11.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3158) PsbQ PF05757.11 EAX91133.1 - 0.035 13.8 0.7 0.035 13.8 0.7 1.3 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) SesA PF17107.5 EAX91133.1 - 0.044 14.0 1.0 0.34 11.1 0.5 2.1 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TLD PF07534.16 EAX91135.1 - 3.9e-36 124.3 0.5 5.9e-36 123.7 0.5 1.3 1 0 0 1 1 1 1 TLD LysM PF01476.20 EAX91135.1 - 3.3e-09 36.7 0.1 1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 LysM domain Ras PF00071.22 EAX91137.1 - 1.2e-46 158.3 0.3 1.4e-46 158.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91137.1 - 1.4e-25 89.8 0.3 2.2e-25 89.2 0.1 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91137.1 - 2.4e-14 53.2 0.2 2.6e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX91137.1 - 3.2e-07 30.4 0.8 0.017 15.0 0.5 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX91137.1 - 0.00024 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX91137.1 - 0.0021 17.5 0.1 0.003 17.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EAX91137.1 - 0.0039 17.7 0.0 0.0099 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAX91137.1 - 0.0052 16.8 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX91137.1 - 0.0057 17.1 0.5 0.02 15.3 0.1 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EAX91137.1 - 0.011 16.0 0.0 0.018 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX91137.1 - 0.025 14.8 0.2 0.054 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EAX91137.1 - 0.029 13.5 0.2 0.056 12.6 0.2 1.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 EAX91137.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX91137.1 - 0.044 13.3 0.3 0.077 12.5 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EAX91137.1 - 0.048 13.6 0.1 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EAX91137.1 - 0.065 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 EAX91137.1 - 0.066 13.5 0.4 3.9 7.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAX91137.1 - 0.077 13.5 0.3 0.11 13.0 0.3 1.6 1 1 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 EAX91137.1 - 0.079 12.5 0.2 2.6 7.6 0.1 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF815 PF05673.13 EAX91137.1 - 0.084 12.0 0.2 0.4 9.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EAX91137.1 - 0.086 13.2 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 EAX91137.1 - 0.095 12.4 0.3 0.7 9.6 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EAX91137.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EAX91138.1 - 2.2e-68 230.5 0.0 3.1e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91138.1 - 1.5e-45 155.6 0.0 2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX91138.1 - 8.5e-10 38.9 1.7 3.3e-05 23.9 0.8 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX91138.1 - 8.8e-07 28.2 2.0 4.7e-06 25.8 2.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAX91138.1 - 1.6e-05 24.6 2.7 5.3e-05 22.9 0.2 2.2 1 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EAX91138.1 - 0.00013 21.4 0.0 0.00095 18.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX91138.1 - 0.00061 18.9 0.0 0.0009 18.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAX91138.1 - 0.0024 17.3 0.2 0.0038 16.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX91138.1 - 0.0043 15.9 0.3 0.0083 14.9 0.3 1.6 1 1 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 EAX91138.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kinase-PolyVal PF18762.1 EAX91138.1 - 0.029 14.3 0.5 0.046 13.7 0.5 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Choline_kinase PF01633.20 EAX91138.1 - 0.046 13.3 0.2 0.093 12.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_5 PF07728.14 EAX91140.1 - 9.9e-79 262.1 0.0 3.3e-21 75.7 0.0 7.8 8 0 0 8 8 7 7 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAX91140.1 - 1.1e-20 73.9 7.9 3.4e-06 26.7 0.1 6.8 6 1 0 6 6 6 4 P-loop containing dynein motor region AAA_22 PF13401.6 EAX91140.1 - 2.9e-19 69.7 0.1 0.0008 19.7 0.0 6.7 5 1 0 5 5 5 4 AAA domain AAA PF00004.29 EAX91140.1 - 2.2e-17 63.7 8.7 0.0038 17.6 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAX91140.1 - 6.4e-16 58.5 0.0 0.00071 19.3 0.0 5.2 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_3 PF07726.11 EAX91140.1 - 3e-14 53.0 0.0 1.7e-06 27.9 0.0 5.8 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX91140.1 - 3.6e-14 53.5 0.0 0.036 14.4 0.0 6.2 6 2 0 6 6 4 3 AAA ATPase domain AAA_14 PF13173.6 EAX91140.1 - 1.9e-12 47.4 11.5 0.00034 20.6 0.0 7.6 7 1 0 7 7 7 3 AAA domain AAA_18 PF13238.6 EAX91140.1 - 1.1e-11 45.3 1.2 0.014 15.9 0.0 6.6 6 0 0 6 6 6 2 AAA domain IstB_IS21 PF01695.17 EAX91140.1 - 9.2e-11 41.8 0.0 0.15 11.7 0.0 5.3 5 0 0 5 5 5 3 IstB-like ATP binding protein T2SSE PF00437.20 EAX91140.1 - 3.9e-10 39.3 1.7 0.0052 15.9 0.1 4.9 5 0 0 5 5 5 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EAX91140.1 - 1.8e-08 34.6 0.0 0.079 13.1 0.0 5.2 5 0 0 5 5 4 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EAX91140.1 - 3.5e-08 33.1 0.4 1.2 8.4 0.0 5.2 5 0 0 5 5 4 3 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAX91140.1 - 3.7e-08 33.7 0.0 0.065 13.4 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 EAX91140.1 - 2e-07 31.5 0.3 0.78 10.1 0.0 5.0 5 0 0 5 5 4 1 AAA domain ATPase_2 PF01637.18 EAX91140.1 - 2.1e-07 31.1 1.7 0.069 13.1 0.0 5.1 4 1 0 4 4 4 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAX91140.1 - 4.5e-07 30.2 2.9 1.4 9.4 0.0 6.1 7 0 0 7 7 5 1 RNA helicase ABC_tran PF00005.27 EAX91140.1 - 9.5e-07 29.4 0.2 0.33 11.4 0.0 4.9 4 0 0 4 4 4 2 ABC transporter NB-ARC PF00931.22 EAX91140.1 - 3e-06 26.6 0.0 0.059 12.5 0.0 3.8 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 EAX91140.1 - 3.3e-06 27.1 0.2 1.3 8.9 0.0 5.4 5 0 0 5 5 5 1 NACHT domain TsaE PF02367.17 EAX91140.1 - 1.1e-05 25.4 0.2 2.6 8.0 0.0 5.2 5 0 0 5 5 5 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EAX91140.1 - 1.3e-05 24.6 0.0 0.85 8.9 0.0 4.3 4 1 0 4 4 4 1 Zeta toxin AAA_30 PF13604.6 EAX91140.1 - 1.8e-05 24.5 0.0 3.2 7.4 0.0 5.2 5 0 0 5 5 5 1 AAA domain RuvB_N PF05496.12 EAX91140.1 - 3.4e-05 23.6 0.9 3 7.6 0.0 5.2 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 EAX91140.1 - 5e-05 22.4 3.6 0.063 12.2 0.1 5.1 6 0 0 6 6 6 1 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 EAX91140.1 - 6.5e-05 22.6 1.3 2.6 7.9 0.0 5.3 6 0 0 6 6 5 1 P-loop containing region of AAA domain Guanylate_kin PF00625.21 EAX91140.1 - 0.00012 21.9 0.0 1.1 8.9 0.0 3.8 3 0 0 3 3 3 1 Guanylate kinase SRP54 PF00448.22 EAX91140.1 - 0.00093 18.9 0.1 2.1 7.9 0.0 3.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EAX91140.1 - 0.0012 18.6 5.3 2.5 7.8 0.0 4.6 4 1 1 5 5 4 2 AAA domain TniB PF05621.11 EAX91140.1 - 0.0016 17.9 0.2 4.7 6.6 0.0 4.3 4 0 0 4 4 4 0 Bacterial TniB protein AAA_28 PF13521.6 EAX91140.1 - 0.0021 18.3 0.5 1.8 8.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EAX91140.1 - 0.0031 17.0 3.3 13 5.1 0.0 4.8 6 0 0 6 6 5 0 PhoH-like protein DEAD PF00270.29 EAX91140.1 - 0.0038 17.0 2.0 20 4.9 0.0 4.7 4 0 0 4 4 4 0 DEAD/DEAH box helicase TIP49 PF06068.13 EAX91140.1 - 0.0046 16.2 1.3 14 4.7 0.0 4.1 4 0 0 4 4 4 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EAX91140.1 - 0.0061 16.3 0.8 0.038 13.7 0.0 2.8 4 0 0 4 4 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EAX91140.1 - 0.008 16.1 1.5 5.3 6.9 0.0 4.9 5 0 0 5 5 5 0 NTPase PduV-EutP PF10662.9 EAX91140.1 - 0.0098 15.6 0.2 0.24 11.2 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EAX91140.1 - 0.015 15.2 0.3 3.5 7.5 0.0 3.9 4 0 0 4 4 3 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EAX91140.1 - 0.015 15.2 0.0 3.6 7.4 0.0 4.3 4 0 0 4 4 4 0 RsgA GTPase AAA_25 PF13481.6 EAX91140.1 - 0.017 14.7 0.8 1.6 8.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 EAX91140.1 - 0.032 14.4 0.1 5.8 7.2 0.0 3.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 EAX91140.1 - 0.1 12.0 1.1 28 4.0 0.0 3.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EAX91140.1 - 0.1 12.2 0.1 9 5.9 0.0 3.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.23 EAX91140.1 - 0.22 11.6 2.8 12 5.9 0.1 4.2 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Guanylate_cyc PF00211.20 EAX91142.1 - 5.3e-17 62.0 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX91142.1 - 0.012 15.8 0.4 0.051 13.8 0.4 2.2 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 EAX91142.1 - 0.046 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain RasGAP PF00616.19 EAX91143.1 - 0.00043 20.1 0.3 0.011 15.5 0.1 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase PH PF00169.29 EAX91144.1 - 0.00019 21.9 1.0 0.00032 21.2 1.0 1.4 1 0 0 1 1 1 1 PH domain PH_TFIIH PF08567.11 EAX91144.1 - 0.00045 20.5 0.3 0.00099 19.4 0.3 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Sharpin_PH PF16764.5 EAX91144.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Sharpin PH domain Ssu72 PF04722.13 EAX91145.1 - 1.4e-56 191.1 0.4 1.6e-56 190.9 0.4 1.0 1 0 0 1 1 1 1 Ssu72-like protein bZIP_1 PF00170.21 EAX91146.1 - 0.0036 17.4 38.0 0.91 9.7 0.4 6.1 5 1 1 6 6 6 4 bZIP transcription factor ATG16 PF08614.11 EAX91146.1 - 0.0037 17.5 14.3 0.0037 17.5 14.3 4.2 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 EAX91146.1 - 0.0054 16.8 3.3 0.0054 16.8 3.3 5.1 2 1 2 5 5 5 3 Afadin- and alpha -actinin-Binding Enolase_C PF00113.22 EAX91146.1 - 0.0099 15.1 2.2 0.0099 15.1 2.2 2.2 2 1 1 3 3 3 1 Enolase, C-terminal TIM barrel domain Cnn_1N PF07989.11 EAX91146.1 - 0.022 14.9 5.5 0.022 14.9 5.5 5.5 2 1 2 5 5 4 0 Centrosomin N-terminal motif 1 Ead_Ea22 PF13935.6 EAX91146.1 - 0.045 14.4 0.2 0.045 14.4 0.2 3.3 2 1 1 3 3 3 0 Ead/Ea22-like protein Cep57_MT_bd PF06657.13 EAX91146.1 - 0.11 13.0 24.5 1.4 9.4 2.6 5.6 3 2 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 EAX91146.1 - 0.33 10.8 55.9 0.28 11.0 3.7 7.4 3 3 4 7 7 7 0 Septum formation initiator GAS PF13851.6 EAX91146.1 - 0.45 9.8 54.3 0.031 13.6 19.8 3.7 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.6 EAX91146.1 - 0.46 10.6 0.1 0.46 10.6 0.1 6.3 7 0 0 7 7 7 0 Sperm tail C-terminal domain Spc7 PF08317.11 EAX91146.1 - 0.64 8.8 55.4 1.2 8.0 20.4 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein HOOK PF05622.12 EAX91146.1 - 1.4 7.0 47.1 0.54 8.4 0.5 3.0 2 1 0 2 2 2 0 HOOK protein Bcr-Abl_Oligo PF09036.10 EAX91146.1 - 6 6.9 10.6 1.3 9.1 0.5 3.9 2 2 2 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain SAVED PF18145.1 EAX91146.1 - 7.3 6.4 6.3 9.2 6.0 0.2 2.6 3 0 0 3 3 3 0 SMODS-associated and fused to various effectors sensor domain CENP-F_leu_zip PF10473.9 EAX91146.1 - 8.5 6.4 52.8 0.74 9.8 2.2 4.5 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTR PF12789.7 EAX91147.1 - 2e-30 104.6 10.7 2e-30 104.6 10.7 4.9 5 1 0 5 5 5 1 Phage tail repeat like HupH_C PF04809.13 EAX91147.1 - 0.077 12.7 0.6 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region DUF4116 PF13475.6 EAX91147.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX91147.1 - 0.21 12.1 11.7 3.1 8.4 3.4 3.3 2 1 0 2 2 2 0 YmaF family DUF1493 PF07377.12 EAX91148.1 - 0.033 14.7 0.5 0.071 13.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91149.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91150.1 - 0.07 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP CarbopepD_reg_2 PF13715.6 EAX91151.1 - 0.061 13.3 0.2 0.32 11.0 0.2 2.2 1 0 0 1 1 1 0 CarboxypepD_reg-like domain AA_permease PF00324.21 EAX91151.1 - 0.069 11.7 0.8 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Amino acid permease EF-hand_1 PF00036.32 EAX91152.1 - 1.2e-22 77.6 11.3 4.9e-08 32.0 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAX91152.1 - 7.8e-21 72.2 5.8 1.8e-05 24.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EAX91152.1 - 2.8e-19 69.3 8.6 4.1e-11 43.2 2.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAX91152.1 - 1.2e-15 57.1 10.4 3.5e-09 36.4 1.2 3.8 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EAX91152.1 - 2.1e-14 52.3 1.9 2.7e-06 26.6 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EAX91152.1 - 8.7e-07 29.2 0.3 0.0011 19.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 EAX91152.1 - 3.5e-06 27.1 2.6 0.0059 16.6 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein EF-hand_4 PF12763.7 EAX91152.1 - 0.0008 19.3 1.9 0.45 10.5 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand T3SS_LEE_assoc PF13327.6 EAX91152.1 - 0.017 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system subunit UPF0223 PF05256.12 EAX91152.1 - 0.1 12.9 0.9 0.68 10.3 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) EF-hand_11 PF08976.11 EAX91152.1 - 0.11 13.4 0.5 2 9.3 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain DUF1456 PF07308.13 EAX91152.1 - 0.12 12.7 0.4 2.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) DUF2232 PF09991.9 EAX91155.1 - 0.26 10.4 6.9 0.39 9.9 6.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF5082 PF16888.5 EAX91156.1 - 0.0033 17.7 27.7 0.0033 17.7 27.7 14.2 1 1 12 15 15 15 5 Domain of unknown function (DUF5082) UPF0242 PF06785.11 EAX91156.1 - 0.0065 16.6 30.1 0.0065 16.6 30.1 12.5 2 1 10 12 12 12 5 Uncharacterised protein family (UPF0242) N-terminus UPF0259 PF06790.11 EAX91156.1 - 0.047 13.5 8.8 0.016 15.0 2.0 3.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) Fringe PF02434.16 EAX91157.1 - 0.05 13.0 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 Fringe-like NAR PF16251.5 EAX91157.1 - 0.064 13.9 0.1 0.19 12.4 0.1 1.8 1 0 0 1 1 1 0 Nucleic acid-binding domain (NAR) DHDPS PF00701.22 EAX91158.1 - 0.16 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Pribosyltran PF00156.27 EAX91159.1 - 1.7e-06 27.7 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EAX91159.1 - 3.5e-05 23.9 0.1 4.5e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain FAS_N PF17828.1 EAX91161.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Spore_coat_CotO PF14153.6 EAX91161.1 - 0.74 9.7 10.5 1 9.2 9.9 1.5 1 1 0 1 1 1 0 Spore coat protein CotO DUF2939 PF11159.8 EAX91162.1 - 0.016 15.6 0.5 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX91163.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX91163.1 - 0.079 13.0 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX91164.1 - 9.7e-25 87.3 7.1 1e-23 84.0 7.0 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAX91166.1 - 7.3e-153 506.9 11.7 9e-153 506.6 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX91166.1 - 0.028 14.1 1.6 2.6 7.7 0.2 2.9 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit NTP_transf_6 PF06042.11 EAX91166.1 - 0.05 13.5 0.6 0.17 11.7 0.1 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX91166.1 - 1.1 9.7 4.7 1.9 9.0 0.6 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX91168.1 - 0.0095 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91169.1 - 1.6e-65 220.2 9.3 5.6e-65 218.4 9.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX91170.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Pox_D5 PF03288.16 EAX91171.1 - 1.1e-05 25.8 1.5 7.8e-05 23.1 1.5 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX91171.1 - 0.0089 16.6 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX91171.1 - 0.013 15.5 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX91172.1 - 4.8e-62 208.1 6.8 5.3e-62 208.0 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX91173.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX91174.1 - 9.8e-07 28.5 2.5 1.4e-06 28.0 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX91174.1 - 0.037 13.7 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX91174.1 - 0.052 13.0 0.1 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX91174.1 - 0.064 13.0 0.2 0.29 10.8 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX91174.1 - 0.082 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX91174.1 - 0.24 11.4 1.8 2.2 8.3 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX91174.1 - 0.6 10.3 8.4 6.1 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX91178.1 - 1.5e-151 502.6 11.5 1.8e-151 502.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX91178.1 - 0.16 11.8 0.8 0.45 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX91178.1 - 1.6 9.2 5.1 3 8.3 0.3 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GvpK PF05121.12 EAX91182.1 - 0.3 11.1 3.8 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K LRR_5 PF13306.6 EAX91183.1 - 3e-107 353.8 167.8 2.4e-15 56.6 14.5 8.7 1 1 10 11 11 11 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91183.1 - 4.8e-09 35.9 12.1 2.6 7.9 0.3 10.5 8 2 5 13 13 13 4 Leucine rich repeat LRR_5 PF13306.6 EAX91184.1 - 2e-76 254.1 91.0 1.1e-16 61.0 8.3 7.6 3 2 4 7 7 7 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91184.1 - 2.1e-06 27.4 14.7 1.9 8.3 0.4 9.7 7 2 3 10 10 10 3 Leucine rich repeat WD40 PF00400.32 EAX91185.1 - 6.8e-13 48.9 9.3 0.00099 19.9 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX91185.1 - 0.0002 21.6 0.0 24 5.3 0.0 5.2 3 3 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX91185.1 - 0.0023 16.9 1.8 0.084 11.8 0.0 3.2 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Bromodomain PF00439.25 EAX91185.1 - 0.012 15.6 0.0 0.072 13.2 0.0 2.3 3 0 0 3 3 3 0 Bromodomain Nup160 PF11715.8 EAX91185.1 - 0.068 11.8 0.1 0.14 10.7 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF1918 PF08940.11 EAX91185.1 - 0.083 12.5 0.1 0.44 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) AKAP28 PF14469.6 EAX91186.1 - 5e-06 26.3 0.2 1e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 28 kDa A-kinase anchor Adipokin_hormo PF06377.11 EAX91187.1 - 0.33 11.3 0.9 5.4 7.5 0.1 2.2 1 1 1 2 2 2 0 Adipokinetic hormone Collagen_bind_2 PF12904.7 EAX91188.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAX91189.1 - 1.8e-65 220.1 13.4 2e-63 213.4 13.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX91189.1 - 0.091 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX91190.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PTR PF12789.7 EAX91192.1 - 2.9e-24 84.9 43.2 7.2e-09 35.6 6.2 5.2 5 0 0 5 5 5 3 Phage tail repeat like DUF4795 PF16043.5 EAX91192.1 - 0.031 13.9 19.1 0.066 12.8 2.3 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4795) PH_TFIIH PF08567.11 EAX91192.1 - 0.56 10.6 3.9 89 3.5 0.1 3.4 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain PA28_alpha PF02251.18 EAX91192.1 - 0.74 9.9 6.9 11 6.2 0.3 3.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit KinB_sensor PF16767.5 EAX91192.1 - 1.3 9.5 4.7 19 5.7 0.2 3.2 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB RraB PF06877.11 EAX91192.1 - 1.8 9.3 7.2 30 5.4 1.2 3.5 2 1 1 3 3 3 0 Regulator of ribonuclease activity B KilA-N PF04383.13 EAX91193.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX91193.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX91193.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX91194.1 - 3e-157 521.3 13.3 3.8e-157 521.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX91194.1 - 1.4 9.5 4.4 1.1 9.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MGC-24 PF05283.11 EAX91195.1 - 0.48 10.9 4.8 0.99 9.9 4.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RhoGAP PF00620.27 EAX91197.1 - 1.8e-30 105.8 0.1 2.5e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain PCI PF01399.27 EAX91198.1 - 6.1e-06 26.7 0.0 1.6e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain LRR_8 PF13855.6 EAX91199.1 - 7.8e-29 99.2 16.8 1.6e-13 50.2 2.1 4.6 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX91199.1 - 1.1e-22 79.7 26.6 2.1e-06 28.0 1.0 6.1 3 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX91199.1 - 7.5e-14 51.6 6.8 1.3e-06 28.0 0.2 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EAX91199.1 - 5e-08 32.4 9.4 0.85 9.8 0.2 6.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EAX91199.1 - 3.8e-06 26.7 14.2 1.2 9.9 1.5 7.1 6 1 0 6 6 6 3 Leucine Rich Repeat Metallothio PF00131.20 EAX91200.1 - 1.6 8.9 72.2 2 8.6 21.5 2.1 1 1 1 2 2 2 0 Metallothionein Reticulon PF02453.17 EAX91201.1 - 0.54 10.2 12.8 0.15 12.0 6.5 2.2 2 0 0 2 2 2 0 Reticulon LRR_5 PF13306.6 EAX91202.1 - 5.6e-13 49.0 1.0 9.5e-06 25.6 0.2 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ras PF00071.22 EAX91203.1 - 4.5e-41 140.2 0.2 5.2e-41 139.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91203.1 - 1.8e-28 99.1 0.4 2.5e-28 98.7 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91203.1 - 5.3e-14 52.1 0.0 6.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX91203.1 - 3.3e-09 36.9 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX91203.1 - 1.2e-05 24.9 0.7 3.4e-05 23.5 0.4 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX91203.1 - 1.7e-05 24.9 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAX91203.1 - 0.00092 18.5 0.1 0.038 13.2 0.0 2.7 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX91203.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX91203.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX91203.1 - 0.0021 17.8 2.0 0.091 12.5 2.0 2.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX91203.1 - 0.0074 15.8 0.1 0.057 12.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EAX91203.1 - 0.042 14.2 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX91203.1 - 0.073 13.3 0.1 0.19 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Astacin PF01400.24 EAX91203.1 - 0.096 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) AAA_7 PF12775.7 EAX91203.1 - 0.12 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 EAX91203.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Myb_DNA-binding PF00249.31 EAX91204.1 - 2.9e-23 81.8 1.1 7.7e-13 48.4 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91204.1 - 1e-15 57.7 6.1 7e-11 42.2 1.8 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91204.1 - 1.6e-05 24.9 2.7 0.0017 18.3 0.2 2.6 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91204.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.6 2 1 0 2 2 2 0 Myb DNA-binding like TPR_1 PF00515.28 EAX91205.1 - 1.6e-59 195.4 31.2 1.4e-10 40.5 0.5 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EAX91205.1 - 3.3e-49 161.0 27.0 1.9e-07 30.7 0.2 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EAX91205.1 - 1.3e-45 152.8 32.4 2.4e-09 36.7 0.1 9.5 7 2 2 9 9 9 7 TPR repeat TPR_8 PF13181.6 EAX91205.1 - 4.5e-33 110.7 21.3 3.2e-06 26.9 0.2 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat STI1 PF17830.1 EAX91205.1 - 4.2e-31 106.7 5.7 1.3e-14 53.9 3.2 3.0 2 0 0 2 2 2 2 STI1 domain TPR_17 PF13431.6 EAX91205.1 - 1.7e-24 84.4 27.2 8e-06 25.9 0.1 9.8 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EAX91205.1 - 1.5e-23 81.4 9.7 0.0042 17.8 0.4 9.4 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAX91205.1 - 2.3e-23 82.6 10.7 9e-05 23.0 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAX91205.1 - 9.8e-23 80.2 19.3 4.4e-07 30.1 1.0 7.7 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAX91205.1 - 1.8e-22 79.6 17.3 0.00018 21.9 0.0 6.7 4 2 1 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EAX91205.1 - 1.2e-14 53.1 8.0 0.91 9.7 0.1 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAX91205.1 - 8.8e-14 51.4 3.7 0.011 15.9 0.8 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EAX91205.1 - 5.1e-08 32.5 20.9 0.35 10.8 0.2 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX91205.1 - 5.6e-07 29.7 11.0 0.0086 16.3 0.1 4.0 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAX91205.1 - 8.5e-07 29.2 14.6 2 9.2 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAX91205.1 - 2.2e-05 24.4 10.5 0.11 12.6 0.1 5.8 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EAX91205.1 - 0.00021 21.3 20.3 0.15 12.1 0.0 7.0 7 1 0 7 7 6 2 MIT (microtubule interacting and transport) domain SRP_TPR_like PF17004.5 EAX91205.1 - 0.0079 16.2 3.6 0.023 14.7 0.3 2.7 3 0 0 3 3 2 1 Putative TPR-like repeat SHNi-TPR PF10516.9 EAX91205.1 - 0.014 14.8 0.2 22 4.6 0.0 4.9 7 0 0 7 7 6 0 SHNi-TPR DUF4471 PF14740.6 EAX91205.1 - 0.021 14.0 1.1 0.037 13.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) HECW1_helix PF18436.1 EAX91205.1 - 0.022 14.8 0.3 0.13 12.4 0.1 2.4 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Alkyl_sulf_dimr PF14863.6 EAX91205.1 - 0.069 13.6 12.2 1.7 9.1 0.1 4.8 3 2 2 5 5 5 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 EAX91205.1 - 0.11 11.5 0.1 7.3 5.5 0.0 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2052 PF09747.9 EAX91205.1 - 4.9 7.2 13.3 7.7 6.6 6.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MAS20 PF02064.15 EAX91205.1 - 5.4 7.1 8.2 34 4.5 2.7 3.5 3 0 0 3 3 3 0 MAS20 protein import receptor TPR_20 PF14561.6 EAX91205.1 - 8.6 6.8 22.6 3.6 8.0 0.0 7.1 4 3 3 8 8 8 0 Tetratricopeptide repeat PSP PF04046.16 EAX91206.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX91207.1 - 0.023 14.7 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX91207.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX91208.1 - 0.025 15.1 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX91208.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX91209.1 - 1.3e-157 522.5 13.9 1.7e-157 522.1 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX91209.1 - 0.12 12.2 1.0 0.36 10.7 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX91209.1 - 1.5 9.3 4.8 4.9 7.7 0.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX91210.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX91210.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX91210.1 - 0.24 10.8 0.6 1.1 8.6 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Amidase02_C PF12123.8 EAX91211.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91212.1 - 2.6e-27 96.0 1.1 3.1e-27 95.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Thioredoxin_8 PF13905.6 EAX91217.1 - 0.14 12.5 3.3 0.46 10.8 2.4 2.5 1 1 0 1 1 1 0 Thioredoxin-like DUF1827 PF08860.10 EAX91217.1 - 2.7 8.3 7.6 14 6.0 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1827) NAPRTase_N PF17767.1 EAX91218.1 - 0.025 15.0 0.1 0.12 12.7 0.1 2.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Acylphosphatase PF00708.18 EAX91219.1 - 1.9e-17 63.4 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase Ank_2 PF12796.7 EAX91220.1 - 3.1e-61 203.9 29.8 3e-13 50.2 2.6 8.0 3 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91220.1 - 5.4e-55 176.9 36.5 8.5e-07 28.8 0.0 14.1 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 EAX91220.1 - 1.8e-54 181.0 27.5 5.6e-13 48.8 0.0 9.7 2 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX91220.1 - 4.1e-54 180.3 29.0 3.3e-09 37.1 0.7 13.0 2 1 12 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 EAX91220.1 - 8.8e-44 146.1 41.9 2.3e-06 27.8 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat DUF3447 PF11929.8 EAX91220.1 - 9.2e-20 70.4 0.3 9.2e-20 70.4 0.3 5.5 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) WAPL PF07814.13 EAX91221.1 - 0.046 12.5 0.7 0.1 11.3 0.7 1.5 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Phage_glycop_gL PF11108.8 EAX91221.1 - 1.1 9.3 4.5 0.9 9.6 0.2 2.8 3 0 0 3 3 3 0 Viral glycoprotein L DUF5640 PF18692.1 EAX91221.1 - 9.9 6.3 8.5 0.99 9.5 1.1 3.0 2 1 2 4 4 4 0 Family of unknown function (DUF5640) Trypan_PARP PF05887.11 EAX91223.1 - 0.041 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.7 EAX91227.1 - 5.4e-19 68.6 6.8 1.7e-09 38.2 0.1 4.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91227.1 - 2.5e-14 53.5 0.4 2.2e-10 40.9 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX91227.1 - 3.1e-13 49.6 0.3 3.1e-08 33.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91227.1 - 7.9e-08 32.4 0.3 6e-05 23.3 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EAX91227.1 - 8.3e-08 31.9 7.1 0.0083 16.6 0.0 6.3 6 2 1 7 7 7 1 Ankyrin repeat Rad60-SLD_2 PF13881.6 EAX91228.1 - 2.3e-05 24.5 0.0 2.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX91228.1 - 6.1e-05 23.5 0.0 7.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EAX91228.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family MatE PF01554.18 EAX91229.1 - 4.9e-26 91.3 18.3 2.5e-16 59.8 2.1 2.5 3 0 0 3 3 3 2 MatE DHHC PF01529.20 EAX91230.1 - 6.8e-14 52.1 4.1 6.8e-14 52.1 4.1 3.1 2 2 0 2 2 2 1 DHHC palmitoyltransferase Fibrillin_U_N PF18193.1 EAX91230.1 - 3.3 7.9 4.8 9.9 6.4 0.3 3.2 3 0 0 3 3 3 0 Fibrillin 1 unique N-terminal domain Aa_trans PF01490.18 EAX91232.1 - 1.7e-18 66.5 39.7 2.1e-18 66.3 39.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ArAE_2_N PF10337.9 EAX91232.1 - 1.6 7.7 12.0 0.017 14.2 2.5 2.1 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Thioredoxin_6 PF13848.6 EAX91233.1 - 2.5e-07 30.8 0.4 0.0024 17.8 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 EAX91233.1 - 3.5e-06 26.9 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EAX91233.1 - 4.3e-05 23.9 0.2 0.13 12.7 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EAX91233.1 - 0.0033 17.5 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain T3SSipB PF16535.5 EAX91234.1 - 0.002 18.6 24.0 0.0033 17.9 2.1 3.8 3 1 0 3 3 3 2 Type III cell invasion protein SipB DUF1664 PF07889.12 EAX91234.1 - 0.011 15.8 3.3 0.011 15.8 3.3 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) DUF730 PF05325.11 EAX91234.1 - 0.037 14.1 0.9 0.037 14.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF4172 PF13776.6 EAX91234.1 - 0.17 12.2 5.9 0.11 12.9 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) Pox_A_type_inc PF04508.12 EAX91234.1 - 1.4 8.9 5.6 9.8 6.2 0.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Bcr-Abl_Oligo PF09036.10 EAX91234.1 - 2.4 8.2 7.6 12 5.9 1.4 3.7 1 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SHIPPO-rpt PF07004.12 EAX91236.1 - 3e-48 160.6 182.2 0.00021 22.1 2.1 24.1 28 0 0 28 28 28 16 Sperm-tail PG-rich repeat Nop10p PF04135.12 EAX91236.1 - 7.5e-11 41.9 24.4 0.034 14.2 0.1 7.5 7 0 0 7 7 7 5 Nucleolar RNA-binding protein, Nop10p family CBM_25 PF03423.13 EAX91236.1 - 7 7.0 11.9 12 6.2 0.1 6.0 4 2 2 6 6 6 0 Carbohydrate binding domain (family 25) SHIPPO-rpt PF07004.12 EAX91237.1 - 5.1e-22 77.7 76.8 0.00017 22.4 1.5 11.8 14 0 0 14 14 14 8 Sperm-tail PG-rich repeat Nop10p PF04135.12 EAX91237.1 - 0.00032 20.7 4.6 0.58 10.2 0.2 3.6 4 0 0 4 4 4 2 Nucleolar RNA-binding protein, Nop10p family Spo0A_C PF08769.11 EAX91238.1 - 0.034 14.2 0.2 0.08 13.0 0.2 1.5 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF4107 PF13389.6 EAX91239.1 - 2e-72 242.6 3.8 2.4e-72 242.4 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX91239.1 - 0.2 10.0 1.0 0.29 9.5 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX91240.1 - 0.022 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase LRR_4 PF12799.7 EAX91241.1 - 0.59 10.6 3.9 1.7 9.2 0.7 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF3447 PF11929.8 EAX91242.1 - 5.1e-12 45.6 6.7 6.6e-12 45.2 2.9 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX91242.1 - 9.8e-06 26.1 0.1 5.1e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91242.1 - 0.023 15.0 0.0 5.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91242.1 - 0.027 15.0 0.0 94 4.1 0.0 4.1 3 1 1 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EAX91242.1 - 0.13 12.8 1.3 33 5.2 0.0 3.9 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Pkinase PF00069.25 EAX91243.1 - 1.7e-59 201.3 0.0 2.2e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91243.1 - 2.8e-41 141.5 0.0 3.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91243.1 - 0.00014 21.3 0.0 0.00047 19.6 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX91243.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX91243.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX91243.1 - 0.0098 14.7 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAX91243.1 - 0.017 14.7 0.3 0.085 12.5 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PglD_N PF17836.1 EAX91243.1 - 0.018 15.6 0.1 0.06 14.0 0.1 1.9 1 0 0 1 1 1 0 PglD N-terminal domain Ribosomal_L7Ae PF01248.26 EAX91243.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 EAX91244.1 - 9.1e-60 202.2 0.1 1.1e-59 202.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91244.1 - 3e-37 128.3 0.0 3.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91244.1 - 1.2e-05 24.8 0.3 0.00065 19.1 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX91244.1 - 0.00047 19.6 0.1 0.00065 19.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX91244.1 - 0.0007 19.2 0.1 0.028 14.0 0.0 2.1 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EAX91244.1 - 0.0014 18.6 0.1 0.0029 17.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX91244.1 - 0.011 14.7 0.2 0.015 14.2 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain PglD_N PF17836.1 EAX91244.1 - 0.018 15.7 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Pkinase_fungal PF17667.1 EAX91244.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L7Ae PF01248.26 EAX91244.1 - 0.028 14.1 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FTA2 PF13095.6 EAX91244.1 - 0.059 13.0 0.3 0.19 11.3 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2299 PF10061.9 EAX91244.1 - 0.098 12.4 0.4 0.26 11.0 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) RNA_binding PF01877.17 EAX91245.1 - 0.032 14.5 0.6 8.3 6.7 0.2 2.4 1 1 1 2 2 2 0 RNA binding Ribosomal_S5 PF00333.20 EAX91246.1 - 1.1e-25 89.3 1.0 2.2e-25 88.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EAX91246.1 - 2.8e-20 71.5 0.0 4.7e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PBP_like PF12727.7 EAX91246.1 - 0.15 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 PBP superfamily domain Ras PF00071.22 EAX91247.1 - 3.2e-45 153.6 0.2 3.9e-45 153.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91247.1 - 6.3e-27 94.2 0.0 9.9e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91247.1 - 1.8e-18 66.6 0.0 2.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX91247.1 - 8.8e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX91247.1 - 3e-08 33.3 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EAX91247.1 - 9.2e-07 28.3 3.5 0.002 17.3 0.1 3.0 2 1 1 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 EAX91247.1 - 1.7e-06 27.7 0.1 0.00021 20.9 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX91247.1 - 0.00035 20.0 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EAX91247.1 - 0.0011 18.7 0.5 0.087 12.5 0.5 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1_Xtn PF16897.5 EAX91247.1 - 0.0019 18.2 0.1 0.0046 17.0 0.1 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EAX91247.1 - 0.0045 16.9 0.9 4.7 7.1 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EAX91247.1 - 0.01 15.9 0.1 0.051 13.6 0.1 2.1 1 1 0 1 1 1 1 Dynamin family AAA_14 PF13173.6 EAX91247.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAX91247.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 EAX91247.1 - 0.046 13.3 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EAX91247.1 - 0.052 13.3 0.2 0.12 12.1 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 EAX91247.1 - 0.079 12.7 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EAX91247.1 - 0.14 12.4 0.3 0.32 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain Fe-ADH PF00465.19 EAX91248.1 - 1.7e-61 208.1 0.0 1.9e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX91248.1 - 4.3e-08 33.2 0.0 6.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Sun2_CC2 PF18580.1 EAX91248.1 - 0.13 12.5 0.5 0.62 10.3 0.1 2.2 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Sun2_CC2 PF18580.1 EAX91249.1 - 0.028 14.6 0.9 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Fe-ADH PF00465.19 EAX91249.1 - 0.092 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Pox_A32 PF04665.12 EAX91259.1 - 3.4e-06 26.7 2.1 3.4e-06 26.7 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX91259.1 - 3.1e-05 24.3 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX91259.1 - 4.3e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX91259.1 - 0.00011 22.3 2.6 0.00023 21.2 2.6 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91259.1 - 0.00054 19.8 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX91259.1 - 0.0018 18.0 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX91259.1 - 0.002 18.0 1.0 0.0039 17.0 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX91259.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX91259.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX91259.1 - 0.069 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX91259.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX91259.1 - 0.092 13.2 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX91259.1 - 0.43 10.9 4.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX91260.1 - 9.8e-155 513.1 12.2 1.2e-154 512.8 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91260.1 - 0.076 13.5 4.6 1.9 9.0 0.3 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX91262.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ORC_WH_C PF18137.1 EAX91263.1 - 8.9e-08 32.3 0.3 0.0031 17.6 0.1 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal DUF4020 PF13212.6 EAX91264.1 - 0.039 13.8 0.7 3.1 7.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) SLC35F PF06027.12 EAX91266.1 - 1.1e-31 110.5 28.8 1.5e-31 110.1 28.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX91266.1 - 6.9e-12 45.7 37.4 1.3e-06 28.6 15.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family CWC25 PF12542.8 EAX91267.1 - 5.5e-15 56.1 4.3 5.5e-15 56.1 4.3 3.0 3 0 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EAX91267.1 - 7.3e-10 38.9 6.8 7.3e-10 38.9 6.8 3.6 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Metallophos PF00149.28 EAX91268.1 - 6.1e-38 131.4 0.2 7.8e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX91268.1 - 2.8e-13 50.1 0.2 5.1e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 EAX91270.1 - 0.0029 18.1 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lum_binding PF00677.17 EAX91270.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Lumazine binding domain DUF4795 PF16043.5 EAX91271.1 - 0.29 10.7 13.8 0.092 12.3 2.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Aurora-A_bind PF09041.10 EAX91271.1 - 0.37 10.9 8.5 5.9 7.0 0.3 3.5 2 2 1 3 3 3 0 Aurora-A binding TM1586_NiRdase PF14512.6 EAX91273.1 - 1.9e-20 73.4 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 EAX91273.1 - 0.00024 21.2 0.0 0.02 15.0 0.0 3.0 3 0 0 3 3 3 1 Nitroreductase family Ank_2 PF12796.7 EAX91274.1 - 4.7e-133 434.1 33.2 1.2e-13 51.5 0.0 16.1 4 4 13 18 18 18 18 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91274.1 - 3.2e-103 336.9 20.2 3.7e-09 36.9 0.1 21.0 12 4 12 25 25 25 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91274.1 - 5.2e-95 299.8 9.8 9.8e-06 25.6 0.0 29.0 31 0 0 31 31 31 18 Ankyrin repeat Ank_5 PF13857.6 EAX91274.1 - 2.7e-92 301.6 18.8 8.7e-06 25.9 0.1 22.4 10 6 12 23 23 23 21 Ankyrin repeats (many copies) Ank PF00023.30 EAX91274.1 - 1.4e-57 189.8 13.1 2.8e-06 27.5 0.1 23.4 23 3 1 24 24 24 15 Ankyrin repeat DUF3447 PF11929.8 EAX91274.1 - 3.7e-06 26.8 26.4 0.015 15.3 2.1 9.0 8 1 1 9 9 9 3 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX91275.1 - 4.7e-08 33.2 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX91275.1 - 1.3e-07 32.0 0.1 1.8e-05 25.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91275.1 - 2.7e-07 30.7 0.3 9.8e-06 25.8 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EAX91275.1 - 1.1e-05 25.9 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91275.1 - 6.9e-05 23.0 0.8 0.0021 18.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Borrelia_P83 PF05262.11 EAX91275.1 - 0.22 10.0 5.8 0.25 9.8 5.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF5099 PF17025.5 EAX91275.1 - 0.24 11.8 3.9 0.2 12.1 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5099) DUF2951 PF11166.8 EAX91275.1 - 0.52 10.6 7.0 0.8 10.0 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Fer2 PF00111.27 EAX91276.1 - 3.8e-09 36.4 0.1 4.8e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ank_2 PF12796.7 EAX91277.1 - 4.3e-38 129.8 11.5 2.5e-13 50.4 0.1 7.9 3 3 0 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91277.1 - 3.7e-35 119.9 10.0 1.6e-06 28.5 0.0 9.1 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91277.1 - 1.2e-27 92.8 16.5 0.0086 16.5 0.0 12.4 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 EAX91277.1 - 4.8e-25 87.3 7.5 0.00061 20.0 0.1 11.2 7 3 5 12 12 12 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX91277.1 - 1.7e-20 72.5 13.2 0.015 15.7 0.0 11.1 11 1 1 12 12 12 6 Ankyrin repeat ubiquitin PF00240.23 EAX91279.1 - 6.7e-11 41.8 0.1 1.4e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Exo5 PF09810.9 EAX91279.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease Rad60-SLD PF11976.8 EAX91279.1 - 0.056 13.3 0.6 0.097 12.5 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX91279.1 - 0.077 12.9 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MitMem_reg PF13012.6 EAX91279.1 - 0.096 13.1 0.6 0.18 12.2 0.4 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function MutS_I PF01624.20 EAX91279.1 - 0.16 12.2 0.0 2 8.7 0.0 2.3 1 1 1 2 2 2 0 MutS domain I LRR_9 PF14580.6 EAX91280.1 - 2.9e-08 33.4 1.3 5e-07 29.4 0.3 2.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EAX91280.1 - 5.1e-06 26.7 3.9 0.00038 20.8 0.6 3.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) DUF2695 PF10905.8 EAX91280.1 - 0.03 14.5 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) NPV_P10 PF05531.12 EAX91281.1 - 0.062 13.8 2.5 4.2 7.9 0.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EAX91281.1 - 0.46 10.8 4.0 4.4 7.6 0.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_IS240 PF13610.6 EAX91281.1 - 0.69 10.1 7.4 0.12 12.6 2.3 2.1 1 1 1 2 2 2 0 DDE domain Uds1 PF15456.6 EAX91281.1 - 2.7 8.2 11.9 1.7 8.8 4.5 2.3 1 1 2 3 3 3 0 Up-regulated During Septation 14-3-3 PF00244.20 EAX91282.1 - 1.4e-73 247.1 7.4 1.5e-73 246.9 7.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EAX91282.1 - 0.0064 17.0 0.6 0.0064 17.0 0.6 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF1653 PF07866.11 EAX91282.1 - 0.055 13.8 0.0 0.49 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1653) RE_CfrBI PF09516.10 EAX91282.1 - 0.07 12.5 4.6 0.054 12.9 1.9 1.9 2 0 0 2 2 2 0 CfrBI restriction endonuclease GLYCAM-1 PF05242.11 EAX91282.1 - 0.075 13.2 0.1 0.25 11.5 0.0 1.9 2 1 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) TPR_8 PF13181.6 EAX91282.1 - 0.41 11.0 6.5 8.1 6.9 0.7 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat HSCB_C PF07743.13 EAX91282.1 - 0.91 10.1 0.1 0.91 10.1 0.1 2.9 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain HEPN_Apea PF18739.1 EAX91283.1 - 0.47 10.9 2.4 0.67 10.4 0.6 2.2 3 0 0 3 3 3 0 Apea-like HEPN Myb_DNA-binding PF00249.31 EAX91284.1 - 3.7e-31 107.1 1.1 1.2e-15 57.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91284.1 - 5.1e-26 90.7 5.8 1.7e-17 63.4 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91284.1 - 1.3e-05 25.1 0.3 0.25 11.4 0.0 3.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX91284.1 - 0.0014 18.7 1.1 0.29 11.3 0.0 3.3 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX91284.1 - 0.0016 18.8 1.9 0.15 12.4 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain PseudoU_synth_1 PF01416.20 EAX91284.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 tRNA pseudouridine synthase HTH_AsnC-type PF13404.6 EAX91284.1 - 0.14 12.0 0.1 0.5 10.2 0.1 2.0 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain Skp1 PF01466.19 EAX91284.1 - 0.14 12.3 4.4 3.3 7.9 0.8 3.7 3 1 1 4 4 4 0 Skp1 family, dimerisation domain DUF1493 PF07377.12 EAX91287.1 - 0.025 15.0 0.5 0.058 13.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91288.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91289.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP COesterase PF00135.28 EAX91290.1 - 2.1e-108 363.5 0.8 1.2e-87 294.9 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAX91290.1 - 9.1e-07 28.9 0.0 8.8e-06 25.7 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAX91290.1 - 0.0021 17.6 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1065 PF06358.11 EAX91291.1 - 4.2 7.4 13.4 1e+02 2.9 0.0 7.3 6 2 1 8 8 8 0 Protein of unknown function (DUF1065) Pkinase_Tyr PF07714.17 EAX91292.1 - 3.2e-57 193.8 0.0 1e-56 192.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX91292.1 - 1.4e-55 188.6 0.0 3.2e-55 187.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain DUF3361 PF11841.8 EAX91292.1 - 0.05 13.5 0.4 1 9.3 0.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) STAT2_C PF12188.8 EAX91292.1 - 0.053 13.5 0.1 0.62 10.0 0.0 2.6 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal Kdo PF06293.14 EAX91292.1 - 0.079 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX91292.1 - 0.092 11.5 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase HEAT_2 PF13646.6 EAX91292.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats HTH_29 PF13551.6 EAX91293.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX91293.1 - 0.065 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE_1 PF03184.19 EAX91294.1 - 5.7e-18 65.2 0.1 9.3e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAX91294.1 - 0.0003 20.6 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Viral_P18 PF04521.13 EAX91295.1 - 0.0075 16.1 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 2 ssRNA positive strand viral 18kD cysteine rich protein PSP PF04046.16 EAX91296.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91297.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Tho2 PF11262.8 EAX91298.1 - 0.084 12.1 1.7 0.092 11.9 1.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spo12 PF05032.12 EAX91298.1 - 8.8 6.3 10.8 0.21 11.5 2.9 2.3 4 0 0 4 4 4 0 Spo12 family Pox_A32 PF04665.12 EAX91300.1 - 5.6e-05 22.7 2.2 5.6e-05 22.7 2.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX91300.1 - 0.004 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX91300.1 - 0.019 14.5 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX91300.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1635 PF07795.11 EAX91301.1 - 0.0037 17.2 2.4 0.0037 17.2 2.4 3.4 1 1 1 3 3 3 1 Protein of unknown function (DUF1635) PSY3 PF16836.5 EAX91301.1 - 0.016 14.7 2.6 0.016 14.7 2.6 2.2 1 1 0 2 2 2 0 Shu complex component Psy3, DNA-binding description Cep57_CLD_2 PF14197.6 EAX91301.1 - 0.018 15.1 12.0 0.018 15.1 12.0 4.5 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 Phage_Mu_Gam PF07352.12 EAX91301.1 - 0.1 12.5 0.4 0.1 12.5 0.4 5.2 1 1 5 6 6 6 0 Bacteriophage Mu Gam like protein DUF4250 PF14056.6 EAX91301.1 - 2.1 8.4 6.3 9 6.3 0.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF3149 PF11346.8 EAX91302.1 - 0.0074 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) TMEM154 PF15102.6 EAX91302.1 - 0.018 15.0 0.2 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 EAX91302.1 - 0.028 14.5 0.1 0.028 14.5 0.1 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4969 PF16339.5 EAX91302.1 - 0.039 14.3 0.8 0.8 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) DUF2207 PF09972.9 EAX91302.1 - 0.04 12.7 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 EAX91302.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MGC-24 PF05283.11 EAX91302.1 - 0.089 13.2 0.4 0.15 12.5 0.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NfeD PF01957.18 EAX91302.1 - 0.09 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF5305 PF17231.2 EAX91302.1 - 0.095 12.1 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) FeoB_associated PF12669.7 EAX91302.1 - 0.13 12.7 0.4 0.18 12.2 0.4 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2939 PF11159.8 EAX91304.1 - 0.016 15.6 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX91304.1 - 3.2 8.4 6.3 7.6 7.2 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF3819 PF12842.7 EAX91307.1 - 0.093 12.7 4.8 0.12 12.3 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF2862 PF11061.8 EAX91307.1 - 0.29 11.0 2.9 15 5.5 2.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2862) Glycoprot_B_PH2 PF17417.2 EAX91307.1 - 2.2 8.7 3.8 32 4.9 3.9 2.1 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain DUF445 PF04286.12 EAX91308.1 - 0.0041 17.0 2.7 0.0047 16.8 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) YpjP PF14005.6 EAX91308.1 - 0.008 16.2 4.1 0.24 11.4 4.1 2.2 1 1 0 1 1 1 1 YpjP-like protein pP_pnuc_2 PF18166.1 EAX91308.1 - 0.12 12.5 9.9 1.2e+02 2.8 9.9 2.6 1 1 0 1 1 1 0 Predicted pPIWI-associating nuclease DUF2862 PF11061.8 EAX91308.1 - 0.14 12.0 7.8 3.5e+02 1.1 7.8 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2862) SecD_SecF PF02355.16 EAX91308.1 - 0.17 11.2 5.2 0.67 9.3 0.3 2.0 1 1 1 2 2 2 0 Protein export membrane protein DUF3819 PF12842.7 EAX91308.1 - 2.9 7.8 19.4 1.2 9.0 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) KilA-N PF04383.13 EAX91309.1 - 4.5e-28 97.3 1.3 7.5e-28 96.6 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX91310.1 - 1.4e-06 28.8 0.6 4.3e-06 27.2 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain KilA-N PF04383.13 EAX91310.1 - 0.11 12.3 1.2 0.51 10.2 0.2 2.4 2 2 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX91310.1 - 0.14 11.6 0.3 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAX91312.1 - 2.6e-07 30.4 0.3 1.8e-06 27.6 0.0 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein TK PF00265.18 EAX91312.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_33 PF13671.6 EAX91312.1 - 0.2 11.8 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.8 EAX91313.1 - 0.0022 17.7 0.1 0.0067 16.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91314.1 - 1.5e-71 239.8 3.7 2.2e-71 239.2 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ras PF00071.22 EAX91316.1 - 1e-36 126.0 0.0 1.3e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91316.1 - 1.6e-27 96.1 0.0 3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAX91316.1 - 1.5e-10 40.9 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EAX91316.1 - 3.8e-10 39.5 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX91316.1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX91316.1 - 2.1e-05 24.5 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EAX91316.1 - 0.0013 18.1 0.1 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 EAX91316.1 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX91316.1 - 0.002 18.6 0.0 0.0037 17.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAX91316.1 - 0.012 15.4 0.2 0.087 12.5 0.0 1.9 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAX91316.1 - 0.017 14.9 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX91316.1 - 0.037 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF463 PF04317.12 EAX91316.1 - 0.044 12.7 0.0 1.7 7.5 0.0 2.1 1 1 0 2 2 2 0 YcjX-like family, DUF463 AAA_5 PF07728.14 EAX91316.1 - 0.051 13.6 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAX91316.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EAX91316.1 - 0.094 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAX91316.1 - 0.13 12.8 1.1 0.17 12.4 1.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EAX91316.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAX91316.1 - 0.18 11.4 1.2 9.7 5.8 0.2 2.6 1 1 2 3 3 3 0 SRP54-type protein, GTPase domain DUF2288 PF10052.9 EAX91317.1 - 0.095 12.8 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Ank_2 PF12796.7 EAX91318.1 - 9.6e-14 51.7 0.1 2.9e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91318.1 - 5.6e-09 36.1 0.4 4.9e-05 23.5 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX91318.1 - 3.4e-08 33.9 0.4 0.068 13.8 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91318.1 - 2.2e-07 30.6 0.1 0.22 12.2 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAX91318.1 - 1.3e-06 28.6 0.1 0.0064 16.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat TSC22 PF01166.18 EAX91318.1 - 0.081 13.3 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA_18 PF13238.6 EAX91319.1 - 2.6e-05 24.8 0.0 7.6e-05 23.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX91319.1 - 0.00029 21.3 0.0 0.00071 20.0 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAX91319.1 - 0.00049 20.4 0.1 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAX91319.1 - 0.00057 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EAX91319.1 - 0.00075 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EAX91319.1 - 0.00095 19.6 0.0 0.0026 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EAX91319.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_17 PF13207.6 EAX91319.1 - 0.0037 17.7 0.0 0.0087 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain ADK PF00406.22 EAX91319.1 - 0.0037 17.4 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase RuvB_N PF05496.12 EAX91319.1 - 0.0039 17.0 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EAX91319.1 - 0.0041 16.7 0.0 0.0092 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAX91319.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAX91319.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 EAX91319.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAX91319.1 - 0.02 15.2 0.6 0.22 11.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EAX91319.1 - 0.024 13.9 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 EAX91319.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 EAX91319.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Mg_chelatase PF01078.21 EAX91319.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 EAX91319.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 EAX91319.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 EAX91319.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EAX91319.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EAX91319.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Ploopntkinase3 PF18751.1 EAX91319.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 EAX91319.1 - 0.2 12.2 0.0 0.47 11.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter CPT PF07931.12 EAX91319.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF4107 PF13389.6 EAX91321.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX91321.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DDE_1 PF03184.19 EAX91324.1 - 7.3e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease LicD PF04991.13 EAX91325.1 - 0.015 15.4 1.4 0.019 15.1 1.4 1.1 1 0 0 1 1 1 0 LicD family Cep57_CLD PF14073.6 EAX91325.1 - 0.029 14.4 2.5 0.039 14.0 2.5 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 ubiquitin PF00240.23 EAX91325.1 - 0.038 13.7 0.6 0.58 9.9 0.0 2.8 2 2 0 2 2 2 0 Ubiquitin family Chal_sti_synt_N PF00195.19 EAX91325.1 - 0.13 11.6 0.7 0.19 11.1 0.7 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Nbl1_Borealin_N PF10444.9 EAX91326.1 - 3.4e-16 58.6 0.0 5.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal LTP_2 PF14368.6 EAX91326.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Probable lipid transfer Lectin_leg-like PF03388.13 EAX91327.1 - 4.9e-20 71.8 0.1 7.1e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF3829 PF12889.7 EAX91327.1 - 0.00015 21.3 3.6 0.00052 19.6 2.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3829) CSTF2_hinge PF14327.6 EAX91328.1 - 9.1e-05 22.8 0.1 0.0001 22.7 0.1 1.1 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DUF771 PF05595.11 EAX91328.1 - 0.019 14.9 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF771) RIIa PF02197.17 EAX91329.1 - 0.00012 21.7 2.8 0.00027 20.6 2.8 1.6 1 1 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Metallophos PF00149.28 EAX91331.1 - 6e-30 105.3 0.1 8.3e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX91331.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MANEC PF07502.14 EAX91331.1 - 0.053 13.8 0.5 0.086 13.1 0.5 1.3 1 0 0 1 1 1 0 MANEC domain ADK PF00406.22 EAX91332.1 - 2.4e-40 138.1 0.0 3e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAX91332.1 - 2e-26 93.0 0.0 3.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAX91332.1 - 5.2e-10 40.0 0.0 9.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAX91332.1 - 0.00056 19.9 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.17 EAX91332.1 - 0.0028 17.4 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 EAX91332.1 - 0.0032 17.6 0.0 0.006 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAX91332.1 - 0.0054 17.0 0.0 0.0077 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EAX91332.1 - 0.0071 16.5 0.3 0.039 14.1 0.2 2.1 2 1 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.15 EAX91332.1 - 0.045 13.7 0.8 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA PF00004.29 EAX91332.1 - 0.065 13.7 0.3 0.21 12.0 0.3 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EAX91332.1 - 0.12 12.7 0.8 0.18 12.2 0.8 1.8 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EAX91332.1 - 0.15 12.4 0.1 0.37 11.1 0.1 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 EAX91332.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAX91332.1 - 0.3 10.8 0.8 1.5 8.5 0.7 2.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Thioredoxin PF00085.20 EAX91334.1 - 9.7e-05 22.3 0.0 0.0042 17.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Ank_5 PF13857.6 EAX91335.1 - 5.9e-18 64.7 0.1 1.3e-08 34.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91335.1 - 4e-17 61.8 2.8 1e-09 38.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX91335.1 - 4.1e-14 52.7 0.2 8.9e-08 32.5 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91335.1 - 5.9e-14 52.4 1.2 9.3e-14 51.8 1.2 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91335.1 - 1.5e-11 43.4 1.5 1.7e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Tctex-1 PF03645.13 EAX91336.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Tctex-1 family RIBIOP_C PF04950.12 EAX91337.1 - 1.9e-60 204.8 0.9 1.9e-60 204.8 0.9 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EAX91337.1 - 5.1e-13 48.9 0.0 2e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EAX91337.1 - 0.00015 22.1 0.1 0.0042 17.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAX91337.1 - 0.00027 21.4 0.0 0.00098 19.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX91337.1 - 0.0004 20.8 0.0 0.0028 18.1 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.27 EAX91337.1 - 0.00063 19.3 0.0 0.00063 19.3 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EAX91337.1 - 0.0017 17.6 0.6 0.063 12.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 EAX91337.1 - 0.0021 18.4 0.0 0.025 14.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EAX91337.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 EAX91337.1 - 0.0051 16.1 1.6 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.22 EAX91337.1 - 0.0067 16.8 0.1 0.036 14.4 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 EAX91337.1 - 0.0091 15.8 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 EAX91337.1 - 0.0099 15.5 0.0 0.52 9.9 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EAX91337.1 - 0.014 15.5 1.6 0.18 11.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAX91337.1 - 0.017 15.6 0.0 0.017 15.6 0.0 3.2 4 0 0 4 4 3 0 ABC transporter Adeno_IVa2 PF02456.15 EAX91337.1 - 0.018 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 EAX91337.1 - 0.037 14.1 0.1 0.28 11.3 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_11 PF13086.6 EAX91337.1 - 0.039 13.7 0.0 0.039 13.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EAX91337.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX91337.1 - 0.065 13.2 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytomega_TRL10 PF06084.11 EAX91337.1 - 0.27 11.2 1.3 0.66 10.0 1.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Endostatin PF06482.11 EAX91337.1 - 5.2 6.4 11.2 0.32 10.4 1.2 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin LRR_6 PF13516.6 EAX91339.1 - 2.2e-24 83.4 45.4 0.00054 19.8 0.2 13.7 14 1 0 14 14 14 9 Leucine Rich repeat LRR_4 PF12799.7 EAX91339.1 - 7.9e-10 38.8 34.7 0.014 15.8 0.1 7.4 5 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX91339.1 - 0.0011 19.1 16.6 4.7 8.1 0.0 8.1 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 EAX91339.1 - 0.044 13.6 34.8 0.023 14.4 3.9 8.3 3 3 2 5 5 5 0 Leucine rich repeat NTF2 PF02136.20 EAX91340.1 - 2.5e-06 28.0 0.0 2.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 EAX91340.1 - 0.054 14.1 0.0 0.059 14.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Nucleopor_Nup85 PF07575.13 EAX91342.1 - 9.7e-07 27.7 0.8 1.6e-05 23.7 0.1 2.1 1 1 0 2 2 2 2 Nup85 Nucleoporin MOZ_SAS PF01853.18 EAX91343.1 - 6.7e-69 231.1 0.2 1.1e-68 230.5 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAX91343.1 - 6.9e-21 73.6 1.6 6.9e-21 73.6 1.6 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAX91343.1 - 1.2e-06 28.3 0.1 2.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 EAX91343.1 - 0.012 16.4 0.8 0.055 14.3 0.8 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Shisa PF13908.6 EAX91344.1 - 3.1e-10 40.6 7.3 6e-10 39.7 7.3 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.6 EAX91344.1 - 0.014 15.8 6.5 0.031 14.7 6.5 1.5 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.6 EAX91344.1 - 0.027 15.3 3.0 0.051 14.5 2.2 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 EAX91344.1 - 0.096 13.0 1.4 0.25 11.7 1.4 1.7 1 0 0 1 1 1 0 Commissureless Prominin PF05478.11 EAX91344.1 - 6.5 4.6 8.4 9.1 4.1 8.4 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_1b PF00579.25 EAX91345.1 - 5.9e-18 65.2 0.0 4.1e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Rhodanese PF00581.20 EAX91346.1 - 1e-11 45.3 0.1 1.8e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF812 PF05667.11 EAX91347.1 - 0.0042 16.1 30.2 0.0055 15.7 30.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4446 PF14584.6 EAX91347.1 - 0.015 15.3 2.1 0.015 15.3 2.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) DUF3584 PF12128.8 EAX91347.1 - 0.82 7.1 36.5 0.18 9.3 15.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF563 PF04577.14 EAX91349.1 - 1.4e-34 120.0 0.8 2.4e-34 119.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Hydrolase_4 PF12146.8 EAX91350.1 - 2e-14 53.5 0.0 5.7e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX91350.1 - 4.7e-10 39.5 0.3 3e-06 27.1 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAX91350.1 - 2.3e-07 31.6 0.0 7.8e-07 29.9 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EAX91350.1 - 6.4e-05 22.7 0.0 0.25 10.9 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EAX91350.1 - 0.00038 20.2 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EAX91350.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EAX91350.1 - 0.044 13.6 0.1 0.2 11.5 0.0 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EAX91350.1 - 0.047 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family G-alpha PF00503.20 EAX91351.1 - 2.8e-85 286.6 2.0 3.7e-85 286.2 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAX91351.1 - 7e-11 41.9 0.4 5.8e-08 32.4 0.1 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX91351.1 - 0.0009 18.7 0.7 0.021 14.2 0.1 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX91351.1 - 0.0051 16.9 0.1 0.38 10.8 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EAX91351.1 - 0.15 12.3 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DDR PF08841.10 EAX91352.1 - 0.056 12.4 0.2 0.057 12.4 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX91353.1 - 0.017 15.1 5.2 0.026 14.5 5.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91353.1 - 4.3 7.8 4.4 6 7.3 4.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX91354.1 - 0.021 14.8 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX91355.1 - 0.027 14.9 0.6 0.035 14.5 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX91355.1 - 4.3 7.3 5.8 4.8 7.2 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4107 PF13389.6 EAX91358.1 - 8e-73 243.9 4.4 9.5e-73 243.7 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX91358.1 - 0.063 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX91358.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX91359.1 - 1.2e-65 217.4 48.7 1e-34 118.3 16.3 5.4 4 2 2 6 6 6 3 Phage tail repeat like Apolipoprotein PF01442.18 EAX91359.1 - 0.11 12.4 2.8 0.18 11.6 2.8 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX91359.1 - 0.18 11.6 0.9 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2897 PF11446.8 EAX91360.1 - 2.1 8.3 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF1493 PF07377.12 EAX91361.1 - 0.07 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91362.1 - 0.088 13.4 5.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91363.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP cwf21 PF08312.12 EAX91364.1 - 8.7e-09 35.4 6.7 1.2e-08 34.9 6.7 1.2 1 0 0 1 1 1 1 cwf21 domain U-box PF04564.15 EAX91364.1 - 0.11 12.7 0.7 8.6 6.6 0.1 2.1 1 1 1 2 2 2 0 U-box domain DUF4542 PF15075.6 EAX91364.1 - 0.12 12.8 0.6 0.14 12.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) LRR_5 PF13306.6 EAX91365.1 - 3.7e-99 327.6 102.4 3.8e-24 85.1 0.7 7.3 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91365.1 - 7.3e-13 48.1 5.9 0.0018 18.0 0.0 10.0 8 3 2 11 11 11 3 Leucine rich repeat LRR_4 PF12799.7 EAX91365.1 - 0.0021 18.4 4.5 3.6 8.1 0.0 7.0 7 2 1 8 8 8 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAX91365.1 - 0.11 12.6 14.3 2.2 8.5 0.0 6.6 5 2 0 5 5 5 0 FNIP Repeat Lactonase PF10282.9 EAX91366.1 - 1.6e-16 60.6 0.1 1.8e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cyc-maltodext_N PF09087.11 EAX91366.1 - 0.0086 16.3 0.2 3.3 8.0 0.0 2.1 1 1 1 2 2 2 2 Cyclomaltodextrinase, N-terminal DUF1292 PF06949.11 EAX91366.1 - 0.024 15.6 0.1 0.031 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) Lactonase PF10282.9 EAX91367.1 - 4.5e-64 216.9 0.0 5e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EAX91367.1 - 0.0024 17.5 0.0 10 5.6 0.0 3.0 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EAX91367.1 - 0.0093 16.1 0.5 2.6 8.3 0.1 3.2 3 1 0 3 3 3 1 Arylesterase PD40 PF07676.12 EAX91367.1 - 0.093 12.7 0.1 5.4 7.1 0.1 3.1 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF4394 PF14339.6 EAX91367.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Spatacsin_C PF14649.6 EAX91368.1 - 5.6e-56 189.9 4.7 1.7e-55 188.3 4.7 1.8 1 0 0 1 1 1 1 Spatacsin C-terminus COR PF16095.5 EAX91368.1 - 0.04 13.7 0.0 0.04 13.7 0.0 3.3 3 0 0 3 3 3 0 C-terminal of Roc, COR, domain UPF0004 PF00919.20 EAX91368.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 HEPN_AbiA_CTD PF18732.1 EAX91368.1 - 0.48 10.4 4.8 0.84 9.6 0.1 3.3 3 0 0 3 3 3 0 HEPN like, Abia C-terminal domain Gly_rich PF12810.7 EAX91369.1 - 4.8e-54 183.9 34.0 5.7e-54 183.6 34.0 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX91370.1 - 2.5e-28 99.6 23.7 3.1e-28 99.4 23.7 1.0 1 0 0 1 1 1 1 Glycine rich protein RNB PF00773.19 EAX91371.1 - 1.9e-91 306.8 1.7 7.9e-91 304.8 0.0 2.1 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EAX91371.1 - 7.3e-18 64.4 0.1 2.2e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EAX91371.1 - 2.5e-06 27.6 0.2 0.00034 20.7 0.1 2.7 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 EAX91371.1 - 3.3e-05 23.8 1.0 0.00016 21.6 1.0 2.3 1 1 0 1 1 1 1 S1 domain PIN_4 PF13638.6 EAX91371.1 - 0.00034 20.9 2.6 0.001 19.3 2.6 1.8 1 0 0 1 1 1 1 PIN domain Lipase_GDSL_3 PF14606.6 EAX91371.1 - 0.035 14.2 0.2 17 5.5 0.0 2.8 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family RabGAP-TBC PF00566.18 EAX91372.1 - 3.1e-05 23.7 5.3 3.9e-05 23.4 1.6 2.2 1 1 1 2 2 2 1 Rab-GTPase-TBC domain FOXO_KIX_bdg PF16675.5 EAX91372.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 Ank_2 PF12796.7 EAX91373.1 - 3.6e-63 210.1 45.8 8.7e-16 58.3 4.1 6.5 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91373.1 - 7.6e-60 198.6 24.4 3.4e-10 40.2 0.1 9.4 1 1 9 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX91373.1 - 2.4e-58 192.2 23.6 4.1e-08 33.3 0.1 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 EAX91373.1 - 2e-43 141.4 25.3 7.3e-06 26.0 0.1 10.2 11 0 0 11 11 10 7 Ankyrin repeat Ank_5 PF13857.6 EAX91373.1 - 2.2e-37 126.6 16.8 8.2e-11 41.9 0.7 6.1 4 2 2 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91373.1 - 1.5e-32 111.3 12.1 1.5e-32 111.3 12.1 3.3 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX91373.1 - 0.00057 20.1 0.0 11 6.4 0.0 3.6 3 1 0 3 3 3 1 N terminal of Calcineurin-like phosphoesterase BRCT_2 PF16589.5 EAX91373.1 - 0.0026 18.1 5.7 5.9 7.4 0.2 4.1 2 1 1 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DUF3718 PF12514.8 EAX91373.1 - 0.028 14.6 5.9 9.2 6.5 0.1 5.7 4 1 3 7 7 7 0 Protein of unknown function (DUF3718) BRCT PF00533.26 EAX91373.1 - 0.12 12.8 0.7 1.2e+02 3.2 0.1 3.8 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PAZ_siRNAbind PF12212.8 EAX91373.1 - 0.3 10.9 4.6 19 5.1 0.1 4.2 2 1 3 5 5 5 0 PAZ domain Ribosomal_S6 PF01250.17 EAX91373.1 - 0.69 10.2 3.6 86 3.5 0.1 4.1 1 1 5 6 6 6 0 Ribosomal protein S6 CbtB PF09489.10 EAX91373.1 - 0.69 10.1 2.5 44 4.3 0.0 3.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) PrmC_N PF17827.1 EAX91373.1 - 0.75 10.4 6.4 55 4.5 0.1 4.7 2 2 3 5 5 5 0 PrmC N-terminal domain CK_II_beta PF01214.18 EAX91374.1 - 2.7e-50 170.7 0.3 3.1e-50 170.5 0.3 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 EAX91374.1 - 0.028 14.7 3.8 0.048 13.9 3.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ribosomal_S24e PF01282.19 EAX91376.1 - 3.5e-29 100.6 0.1 5.7e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAX91376.1 - 0.00059 19.7 0.7 0.001 18.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) FAS_N PF17828.1 EAX91377.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX91378.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX91378.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PadR PF03551.14 EAX91379.1 - 0.13 12.3 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF3839 PF12943.7 EAX91380.1 - 2.2e-147 489.0 14.7 2.8e-147 488.7 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91380.1 - 1.1 9.7 5.3 1.5 9.3 0.2 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Acetyltransf_1 PF00583.25 EAX91382.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_17 PF17668.1 EAX91382.1 - 0.007 17.2 0.1 0.011 16.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF496 PF04363.12 EAX91382.1 - 0.091 12.8 0.5 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Profilin PF00235.19 EAX91384.1 - 2e-18 66.9 0.3 2.2e-18 66.8 0.3 1.0 1 0 0 1 1 1 1 Profilin Hydrolase_6 PF13344.6 EAX91385.1 - 2.8e-24 85.1 0.0 4.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX91385.1 - 2.1e-19 69.3 0.0 9.5e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EAX91385.1 - 8e-10 39.4 0.2 0.00066 20.0 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAX91385.1 - 4.2e-05 23.7 0.0 0.096 12.8 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EAX91385.1 - 0.00047 19.8 0.1 0.0049 16.5 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD PF12710.7 EAX91385.1 - 0.025 15.0 0.1 0.091 13.1 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Reg_prop PF07494.11 EAX91385.1 - 0.089 13.1 0.0 0.4 11.0 0.0 2.2 1 0 0 1 1 1 0 Two component regulator propeller SIR2 PF02146.17 EAX91386.1 - 3.5e-40 137.8 0.0 5.5e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EAX91386.1 - 0.022 14.5 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Peptidase_S49_N PF08496.10 EAX91386.1 - 0.04 14.0 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Trypan_PARP PF05887.11 EAX91388.1 - 0.09 12.8 11.3 0.14 12.1 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91388.1 - 7.7 7.0 6.1 11 6.4 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX91389.1 - 0.026 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX91390.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX91390.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX91391.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX91391.1 - 0.072 13.1 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TPR_MLP1_2 PF07926.12 EAX91392.1 - 0.012 15.7 0.8 0.015 15.4 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX91392.1 - 0.44 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DHHC PF01529.20 EAX91393.1 - 3.5e-21 75.7 9.8 3.5e-21 75.7 9.8 3.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase RPAP1_C PF08620.10 EAX91393.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RPAP1-like, C-terminal Gryzun-like PF12742.7 EAX91394.1 - 1.2e-24 86.0 0.0 4.6e-24 84.2 0.0 2.1 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF2117 PF09890.9 EAX91394.1 - 2.4e-05 23.9 0.5 5.8e-05 22.7 0.4 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2117) TRAPPC10 PF12584.8 EAX91394.1 - 2.4e-05 24.1 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF5390 PF17365.2 EAX91394.1 - 0.0045 17.3 3.9 0.0055 17.0 2.3 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5390) HMG_box_2 PF09011.10 EAX91395.1 - 0.00015 22.3 3.6 0.13 12.9 0.1 3.9 3 1 1 4 4 4 2 HMG-box domain HMG_box PF00505.19 EAX91395.1 - 0.2 12.1 14.0 1.2 9.6 0.8 5.0 5 0 0 5 5 5 0 HMG (high mobility group) box DUF1642 PF07852.11 EAX91397.1 - 0.052 14.1 0.1 0.07 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Thioredoxin PF00085.20 EAX91399.1 - 2.5e-16 59.5 0.0 8.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EAX91399.1 - 3.7e-09 37.0 1.0 8.3e-05 23.0 0.2 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EAX91399.1 - 5e-05 23.3 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 EAX91399.1 - 5.8e-05 23.0 0.0 0.061 13.3 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EAX91399.1 - 0.00013 22.1 0.3 0.00054 20.1 0.0 2.1 2 1 0 2 2 2 1 Glutaredoxin TraF PF13728.6 EAX91399.1 - 0.00052 19.9 0.2 0.87 9.4 0.1 3.1 2 1 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EAX91399.1 - 0.00067 19.9 1.0 3.3 8.1 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EAX91399.1 - 0.0018 18.4 0.1 0.0064 16.6 0.1 2.0 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 EAX91399.1 - 0.0023 18.1 2.1 0.062 13.5 2.1 2.2 1 1 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 EAX91399.1 - 0.023 14.3 0.0 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TrbC_Ftype PF09673.10 EAX91399.1 - 0.025 14.6 0.0 6.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein FPP PF05911.11 EAX91401.1 - 8.9e-05 20.9 48.2 8.9e-05 20.9 48.2 3.0 1 1 2 3 3 3 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 EAX91401.1 - 0.00058 19.9 19.1 0.00058 19.9 19.1 6.9 1 1 5 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 EAX91401.1 - 0.00098 19.1 11.7 0.00098 19.1 11.7 8.9 4 2 4 9 9 9 4 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 EAX91401.1 - 0.0011 19.3 11.0 0.0011 19.3 11.0 7.1 1 1 6 7 7 7 2 Plant protein of unknown function (DUF641) Spc7 PF08317.11 EAX91401.1 - 0.0038 16.2 22.5 0.0038 16.2 22.5 5.2 1 1 4 5 5 5 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAX91401.1 - 0.014 15.4 23.2 0.014 15.4 23.2 6.8 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EAX91401.1 - 0.18 12.4 0.2 0.18 12.4 0.2 8.8 5 4 4 9 9 9 0 SlyX Lebercilin PF15619.6 EAX91401.1 - 0.4 10.3 90.3 2.5 7.7 18.6 5.3 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Rootletin PF15035.6 EAX91401.1 - 4.2 7.3 79.7 1 9.4 8.6 5.1 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 EAX91401.1 - 7.7 7.0 105.8 0.41 11.2 7.3 6.8 2 1 5 7 7 7 0 Apg6 coiled-coil region TruD PF01142.18 EAX91402.1 - 1e-66 225.5 8.6 2.7e-62 211.0 7.2 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF2004 PF09406.10 EAX91402.1 - 0.36 11.2 2.4 24 5.3 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2004) IFT57 PF10498.9 EAX91403.1 - 0.017 14.1 0.6 0.021 13.8 0.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ATP-synt_D PF01813.17 EAX91403.1 - 0.018 14.8 1.1 0.027 14.3 0.5 1.5 1 1 1 2 2 2 0 ATP synthase subunit D FliD_C PF07195.12 EAX91403.1 - 0.02 14.3 0.4 0.024 14.1 0.4 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HBD PF18534.1 EAX91403.1 - 0.027 14.6 0.3 0.067 13.3 0.2 1.7 1 1 0 1 1 1 0 Helical bundle domain COG2 PF06148.11 EAX91403.1 - 0.059 13.5 0.3 0.083 13.0 0.3 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.11 EAX91403.1 - 0.059 13.5 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PPARgamma_N PF12577.8 EAX91403.1 - 0.062 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 PPAR gamma N-terminal region Ribonuclease_3 PF00636.26 EAX91403.1 - 0.1 13.2 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease III domain ING PF12998.7 EAX91403.1 - 0.11 13.1 1.7 2.4 8.8 0.2 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding HMG_box PF00505.19 EAX91404.1 - 6.7e-13 48.8 1.0 1.1e-12 48.1 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX91404.1 - 6.6e-08 33.0 1.3 9.9e-08 32.5 0.3 1.7 1 1 0 1 1 1 1 HMG-box domain DUF5623 PF18536.1 EAX91405.1 - 0.061 13.6 0.2 0.081 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX91405.1 - 0.092 12.7 2.7 0.092 12.7 2.7 2.4 3 0 0 3 3 3 0 Spo12 family DUF563 PF04577.14 EAX91406.1 - 7.3e-30 104.7 0.2 1.1e-29 104.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PI3K_P85_iSH2 PF16454.5 EAX91407.1 - 2.7e-05 23.8 2.1 4e-05 23.3 2.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_13 PF13166.6 EAX91407.1 - 0.00017 20.5 4.8 0.00019 20.2 4.8 1.1 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 EAX91407.1 - 0.0013 19.3 3.0 0.002 18.7 3.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region ADIP PF11559.8 EAX91407.1 - 0.0014 18.7 3.2 0.0023 18.0 3.2 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 EAX91407.1 - 0.0015 18.9 2.0 0.0019 18.5 2.0 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Spc7 PF08317.11 EAX91407.1 - 0.0021 17.0 2.8 0.0027 16.6 2.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 EAX91407.1 - 0.0023 16.9 2.0 0.0024 16.8 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TSC22 PF01166.18 EAX91407.1 - 0.0027 18.0 3.7 0.0059 16.9 3.7 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF4600 PF15372.6 EAX91407.1 - 0.0053 17.2 2.3 0.008 16.6 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) HAP1_N PF04849.13 EAX91407.1 - 0.0071 15.6 4.3 0.01 15.1 4.3 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Fez1 PF06818.15 EAX91407.1 - 0.0096 16.4 2.0 0.012 16.0 2.0 1.2 1 0 0 1 1 1 1 Fez1 CorA PF01544.18 EAX91407.1 - 0.011 15.0 0.3 0.018 14.4 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF724 PF05266.14 EAX91407.1 - 0.011 15.5 1.5 0.016 15.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 EAX91407.1 - 0.017 15.4 3.1 0.025 14.8 3.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spectrin PF00435.21 EAX91407.1 - 0.02 15.4 0.4 0.03 14.8 0.4 1.4 1 0 0 1 1 1 0 Spectrin repeat BRE1 PF08647.11 EAX91407.1 - 0.021 14.9 6.0 0.039 14.0 6.0 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 EAX91407.1 - 0.022 14.9 5.2 0.036 14.2 5.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Ax_dynein_light PF10211.9 EAX91407.1 - 0.024 14.6 4.2 0.036 14.0 4.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain PspA_IM30 PF04012.12 EAX91407.1 - 0.032 13.8 0.4 0.043 13.4 0.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF3287 PF11690.8 EAX91407.1 - 0.05 13.3 0.7 0.18 11.5 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) FapA PF03961.13 EAX91407.1 - 0.054 12.1 3.8 0.061 11.9 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 EAX91407.1 - 0.058 13.8 1.6 0.11 12.9 1.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) LPP PF04728.13 EAX91407.1 - 0.058 13.8 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper P4Ha_N PF08336.11 EAX91407.1 - 0.071 13.1 4.1 0.13 12.3 3.8 1.5 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3450 PF11932.8 EAX91407.1 - 0.08 12.2 2.6 0.11 11.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EAX91407.1 - 0.08 13.1 7.3 0.15 12.2 5.8 2.0 1 1 1 2 2 2 0 bZIP transcription factor DUF2203 PF09969.9 EAX91407.1 - 0.093 13.5 0.9 0.14 12.9 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 EAX91407.1 - 0.1 11.5 2.0 0.13 11.1 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EMP24_GP25L PF01105.24 EAX91407.1 - 0.21 11.5 6.5 0.34 10.8 6.5 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 EAX91407.1 - 0.27 11.7 4.8 0.9 10.0 4.8 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 EAX91407.1 - 0.29 11.6 5.9 0.54 10.7 5.9 1.4 1 0 0 1 1 1 0 Cell division protein ZapB NPV_P10 PF05531.12 EAX91407.1 - 0.56 10.7 5.1 1.3 9.5 5.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SIX1_SD PF16878.5 EAX91407.1 - 0.62 10.6 4.8 0.64 10.6 1.7 2.1 1 1 1 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain IFP_35_N PF07334.13 EAX91407.1 - 1.2 9.3 8.1 2.1 8.5 3.7 2.5 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.15 EAX91407.1 - 2.7 7.8 6.7 9.5 6.1 4.9 2.2 1 1 1 2 2 2 0 Septum formation initiator PHD PF00628.29 EAX91408.1 - 3.4e-08 33.3 29.2 0.00027 20.8 4.4 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EAX91408.1 - 0.00035 20.0 1.3 0.00035 20.0 1.3 2.5 2 0 0 2 2 2 1 PHD-finger zf-CCHC_2 PF13696.6 EAX91408.1 - 0.047 13.5 0.3 0.047 13.5 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle AUX_IAA PF02309.16 EAX91408.1 - 2.7 7.8 9.3 4.2 7.1 9.3 1.2 1 0 0 1 1 1 0 AUX/IAA family Ank_4 PF13637.6 EAX91409.1 - 1.2e-101 331.8 43.2 4.9e-13 49.3 0.2 16.4 2 2 15 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 EAX91409.1 - 4.7e-98 317.7 43.3 2.4e-08 34.1 0.2 15.5 15 0 0 15 15 15 15 Ankyrin repeat Ank_2 PF12796.7 EAX91409.1 - 2.5e-97 319.6 55.6 3.8e-16 59.4 1.2 9.2 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91409.1 - 7.3e-82 259.5 35.9 1.8e-05 24.7 0.0 16.0 17 0 0 17 17 16 15 Ankyrin repeat Ank_5 PF13857.6 EAX91409.1 - 4.9e-74 243.4 38.0 8.4e-11 41.9 0.7 11.7 7 2 5 12 12 12 11 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91409.1 - 4.9e-25 87.3 33.1 3.2e-23 81.5 6.4 6.0 3 2 4 7 7 7 3 Domain of unknown function (DUF3447) LEM PF03020.15 EAX91409.1 - 0.0002 20.9 0.0 11 5.6 0.0 6.0 7 0 0 7 7 7 1 LEM domain BCS1_N PF08740.11 EAX91409.1 - 0.00046 20.2 1.4 0.48 10.4 0.1 3.6 3 3 2 5 5 5 2 BCS1 N terminal MCC-bdg_PDZ PF10506.9 EAX91409.1 - 1.2 9.2 7.2 37 4.4 0.0 5.7 6 0 0 6 6 6 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3718 PF12514.8 EAX91409.1 - 2.7 8.2 15.3 31 4.8 0.1 6.2 6 2 1 7 7 7 0 Protein of unknown function (DUF3718) DUF1947 PF09183.10 EAX91409.1 - 6.9 7.1 5.8 80 3.6 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1947) LRR_4 PF12799.7 EAX91411.1 - 1.5e-24 85.7 73.0 1.2e-06 28.8 2.0 11.2 5 3 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX91411.1 - 1.6e-24 85.4 52.9 8.6e-09 35.0 4.0 9.5 7 3 2 9 9 9 7 Leucine rich repeat LRR_6 PF13516.6 EAX91411.1 - 2.6e-08 33.3 38.0 0.77 10.0 0.1 13.7 15 0 0 15 15 15 4 Leucine Rich repeat LRR_1 PF00560.33 EAX91411.1 - 0.00061 20.0 55.6 6.8 7.7 0.2 14.4 11 5 1 12 12 12 2 Leucine Rich Repeat SwrA PF17423.2 EAX91411.1 - 0.35 10.9 7.3 0.39 10.7 0.1 3.7 4 0 0 4 4 4 0 Swarming motility protein LRR_3 PF07725.12 EAX91411.1 - 0.43 10.5 4.0 22 5.1 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat CDC45 PF02724.14 EAX91412.1 - 0.43 8.8 16.5 0.53 8.5 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GPCR_chapero_1 PF11904.8 EAX91412.1 - 1.7 8.0 15.2 3.1 7.2 15.2 1.4 1 0 0 1 1 1 0 GPCR-chaperone PA26 PF04636.13 EAX91412.1 - 2.7 6.8 11.1 3.3 6.5 11.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GAGA_bind PF06217.12 EAX91412.1 - 3.1 8.0 16.0 3.8 7.7 16.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIID PF08486.10 EAX91412.1 - 4.2 8.0 7.3 8 7.1 7.4 1.5 1 1 0 1 1 1 0 Stage II sporulation protein DUF743 PF05332.11 EAX91412.1 - 9.7 6.3 12.9 0.43 10.6 2.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF743) Vac_Fusion PF02346.16 EAX91413.1 - 0.18 11.5 5.8 66 3.2 0.2 4.6 1 1 4 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 CLAMP PF14769.6 EAX91413.1 - 1.3 9.5 15.7 1.5 9.3 3.6 3.6 2 2 1 3 3 3 0 Flagellar C1a complex subunit C1a-32 DUF3231 PF11553.8 EAX91413.1 - 4.7 6.8 15.8 7.9 6.1 0.7 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3231) KASH_CCD PF14662.6 EAX91414.1 - 8.1e-07 29.1 53.1 0.003 17.4 7.0 4.4 1 1 3 4 4 4 3 Coiled-coil region of CCDC155 or KASH IFT57 PF10498.9 EAX91414.1 - 0.00042 19.4 47.6 0.0028 16.7 25.4 3.1 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 DivIC PF04977.15 EAX91414.1 - 0.0009 19.0 46.2 0.01 15.6 2.7 7.2 5 3 1 6 6 6 2 Septum formation initiator EzrA PF06160.12 EAX91414.1 - 0.0014 16.9 46.9 0.018 13.2 24.8 3.2 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA CEP63 PF17045.5 EAX91414.1 - 0.0014 18.5 30.1 0.0014 18.5 30.1 2.6 1 1 1 2 2 2 1 Centrosomal protein of 63 kDa PRKG1_interact PF15898.5 EAX91414.1 - 0.0019 19.1 11.4 0.0019 19.1 11.4 5.3 2 2 1 3 3 2 1 cGMP-dependent protein kinase interacting domain YabA PF06156.13 EAX91414.1 - 0.0028 18.3 49.5 0.023 15.3 6.2 6.2 1 1 5 6 6 6 2 Initiation control protein YabA DUF285 PF03382.14 EAX91414.1 - 0.0031 17.3 6.9 0.0031 17.3 6.9 3.2 1 1 2 3 3 3 1 Mycoplasma protein of unknown function, DUF285 Fez1 PF06818.15 EAX91414.1 - 0.0087 16.5 46.3 0.17 12.3 26.9 3.8 1 1 0 2 2 2 2 Fez1 Filament PF00038.21 EAX91414.1 - 0.01 15.4 47.9 0.068 12.8 25.0 3.1 1 1 2 3 3 3 0 Intermediate filament protein kleA_kleC PF17383.2 EAX91414.1 - 0.017 15.4 8.4 0.31 11.4 0.3 3.9 1 1 4 5 5 4 0 Uncharacterized KorC regulated protein A SlyX PF04102.12 EAX91414.1 - 0.02 15.5 3.1 0.02 15.5 3.1 7.1 4 2 2 6 6 6 0 SlyX HrpB7 PF09486.10 EAX91414.1 - 0.026 14.9 1.7 0.026 14.9 1.7 3.7 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF724 PF05266.14 EAX91414.1 - 0.026 14.4 41.3 0.14 11.9 7.5 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF724) APG6_N PF17675.1 EAX91414.1 - 0.06 13.9 48.6 0.11 13.1 12.9 5.3 1 1 3 4 4 3 0 Apg6 coiled-coil region RVT_3 PF13456.6 EAX91414.1 - 0.064 13.1 2.0 8.6 6.2 0.0 3.4 3 0 0 3 3 3 0 Reverse transcriptase-like Spc7 PF08317.11 EAX91414.1 - 0.066 12.1 53.0 0.0078 15.1 18.3 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 EAX91414.1 - 0.072 12.7 34.4 0.076 12.6 3.5 4.3 1 1 3 4 4 4 0 PspA/IM30 family Leu_zip PF15294.6 EAX91414.1 - 0.1 12.1 50.6 0.034 13.7 7.4 3.9 1 1 2 3 3 3 0 Leucine zipper HBD PF18534.1 EAX91414.1 - 0.13 12.4 6.8 0.29 11.3 0.4 3.5 3 0 0 3 3 3 0 Helical bundle domain PE PF00934.20 EAX91414.1 - 0.14 12.5 4.4 16 5.9 0.0 3.8 5 0 0 5 5 3 0 PE family HMMR_N PF15905.5 EAX91414.1 - 0.14 11.6 52.4 0.33 10.4 16.0 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 EAX91414.1 - 0.15 11.1 51.3 0.081 12.0 8.2 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EAX91414.1 - 0.23 11.5 53.4 0.045 13.8 9.4 6.2 1 1 5 6 6 6 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EAX91414.1 - 0.24 11.5 38.5 0.65 10.1 1.7 5.2 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 EAX91414.1 - 0.85 9.6 18.5 54 3.9 0.1 7.7 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat ZapB PF06005.12 EAX91414.1 - 0.9 10.0 59.3 0.17 12.3 8.3 6.8 2 2 2 5 5 5 0 Cell division protein ZapB GTP-bdg_M PF16360.5 EAX91414.1 - 0.95 10.1 17.5 21 5.8 0.0 6.0 5 2 0 5 5 5 0 GTP-binding GTPase Middle Region DUF4472 PF14739.6 EAX91414.1 - 0.98 10.2 44.6 1.4 9.7 0.3 5.5 1 1 5 6 6 6 0 Domain of unknown function (DUF4472) CdvA PF18822.1 EAX91414.1 - 1.1 9.1 34.1 0.12 12.2 10.6 5.2 3 2 2 5 5 5 0 CdvA-like coiled-coil domain CCDC92 PF14916.6 EAX91414.1 - 1.2 9.0 16.4 0.19 11.5 0.4 5.2 5 1 1 6 6 6 0 Coiled-coil domain of unknown function Pedibin PF08182.11 EAX91414.1 - 1.3 8.9 10.9 35 4.3 0.1 4.8 4 1 0 4 4 4 0 Pedibin/Hym-346 family DUF3450 PF11932.8 EAX91414.1 - 1.5 8.1 51.1 0.098 11.9 3.6 4.9 1 1 3 4 4 3 0 Protein of unknown function (DUF3450) DUF4474 PF14751.6 EAX91414.1 - 1.7 8.0 6.8 0.3 10.5 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) GIT_CC PF16559.5 EAX91414.1 - 1.9 8.4 51.1 0.062 13.2 3.9 7.1 6 1 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 EAX91414.1 - 2.2 8.5 46.2 0.025 14.7 3.5 6.5 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 TipAS PF07739.13 EAX91414.1 - 2.7 8.6 17.1 0.25 11.9 0.4 4.4 2 2 3 5 5 5 0 TipAS antibiotic-recognition domain YtxH PF12732.7 EAX91414.1 - 2.7 8.6 16.8 4 8.0 0.6 4.8 3 1 0 3 3 3 0 YtxH-like protein DUF4795 PF16043.5 EAX91414.1 - 2.9 7.5 43.7 1.3 8.6 5.2 3.5 1 1 1 2 2 1 0 Domain of unknown function (DUF4795) DUF5595 PF18077.1 EAX91414.1 - 3 8.0 21.3 4.8 7.3 0.1 5.6 4 2 2 6 6 6 0 Domain of unknown function (DUF5595) HAUS-augmin3 PF14932.6 EAX91414.1 - 3.3 7.2 45.9 0.14 11.7 17.6 4.1 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 EAX91414.1 - 3.3 7.9 47.5 0.076 13.2 14.8 4.5 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 ApoC-I PF04691.12 EAX91414.1 - 4.9 7.2 8.1 11 6.0 0.1 4.4 3 2 2 5 5 4 0 Apolipoprotein C-I (ApoC-1) PKcGMP_CC PF16808.5 EAX91414.1 - 6.1 6.8 10.5 25 4.9 0.1 5.3 6 0 0 6 6 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MCC-bdg_PDZ PF10506.9 EAX91414.1 - 9.7 6.3 20.7 2.9 8.0 3.8 5.0 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ATP_transf PF09830.9 EAX91415.1 - 2.3e-08 34.0 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase ubiquitin PF00240.23 EAX91416.1 - 5.4e-16 58.1 1.1 1e-15 57.2 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX91416.1 - 0.016 15.0 1.5 0.032 14.1 1.5 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX91416.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX91416.1 - 0.071 13.2 0.0 0.35 11.0 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 EAX91418.1 - 2.3e-59 200.9 0.0 3.2e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91418.1 - 8.2e-39 133.4 0.0 2.1e-38 132.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91418.1 - 0.00047 19.6 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX91418.1 - 0.0011 17.9 0.0 0.0026 16.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAX91418.1 - 0.0036 16.7 0.1 0.0077 15.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX91418.1 - 0.027 13.4 0.2 0.053 12.5 0.2 1.5 1 0 0 1 1 1 0 Haspin like kinase domain CBM_20 PF00686.19 EAX91419.1 - 0.0062 16.4 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Glyco_hydro_77 PF02446.17 EAX91420.1 - 4.1e-149 497.4 3.3 5.3e-149 497.0 3.3 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAX91420.1 - 3.7e-51 171.0 0.0 8.4e-22 76.9 0.0 3.6 3 0 0 3 3 3 3 Starch binding domain Peptidase_C1 PF00112.23 EAX91421.1 - 3.4e-72 243.1 9.3 4.3e-72 242.7 9.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX91421.1 - 2.2e-09 37.6 0.0 4.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAX91421.1 - 0.0022 16.8 1.1 0.7 8.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DHHW PF14286.6 EAX91421.1 - 0.041 13.2 0.1 1 8.6 0.0 2.6 2 1 0 3 3 3 0 DHHW protein MCM PF00493.23 EAX91422.1 - 1.3e-97 325.3 0.1 2.1e-97 324.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAX91422.1 - 4.9e-30 104.0 0.0 1e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAX91422.1 - 3.5e-25 88.3 0.1 1.1e-24 86.6 0.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAX91422.1 - 8.5e-12 45.6 0.1 5.3e-11 43.0 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAX91422.1 - 2.3e-05 23.9 0.1 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EAX91422.1 - 0.0048 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EAX91422.1 - 0.01 16.5 0.2 0.044 14.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_5 PF07728.14 EAX91422.1 - 0.012 15.7 0.0 0.083 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Gly_rich PF12810.7 EAX91423.1 - 3.6e-51 174.4 35.5 4.4e-51 174.1 35.5 1.1 1 0 0 1 1 1 1 Glycine rich protein Toxin_21 PF08091.11 EAX91423.1 - 0.091 12.7 0.2 0.091 12.7 0.2 2.0 2 0 0 2 2 2 0 Spider insecticidal peptide Gamma-thionin PF00304.20 EAX91423.1 - 0.65 10.3 3.9 0.36 11.1 0.6 2.3 2 0 0 2 2 2 0 Gamma-thionin family Pkinase PF00069.25 EAX91424.1 - 3.9e-58 196.9 0.0 8e-57 192.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91424.1 - 4.9e-57 193.2 0.0 1e-56 192.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX91424.1 - 0.0038 16.1 0.0 0.0068 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX91424.1 - 0.0078 15.6 0.3 0.092 12.1 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_M PF14666.6 EAX91424.1 - 0.026 14.3 1.1 0.29 10.9 0.0 3.2 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain RIO1 PF01163.22 EAX91424.1 - 0.11 12.1 0.3 5.5 6.6 0.0 2.7 2 0 0 2 2 2 0 RIO1 family PB1 PF00564.24 EAX91425.1 - 0.013 15.4 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 PB1 domain Ig_3 PF13927.6 EAX91425.1 - 0.056 14.1 0.0 11 6.7 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin domain LRR_5 PF13306.6 EAX91427.1 - 4.7e-12 46.0 2.8 4.7e-12 46.0 2.8 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91427.1 - 1.5e-07 31.1 1.4 0.00013 21.6 0.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EAX91427.1 - 0.0024 18.2 0.6 0.07 13.6 0.4 3.6 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) ATP_bind_3 PF01171.20 EAX91428.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.5 1 1 0 1 1 1 0 PP-loop family CSTF1_dimer PF16699.5 EAX91428.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain RIX1 PF08167.12 EAX91429.1 - 2.9e-05 23.9 3.7 1.6 8.4 0.0 5.1 3 2 1 4 4 4 2 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EAX91429.1 - 0.00023 21.0 0.1 0.0011 18.9 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EAX91429.1 - 0.00045 20.6 2.6 0.72 10.3 0.0 4.1 4 1 0 4 4 4 2 HEAT repeats IFRD PF05004.13 EAX91429.1 - 0.0018 17.5 0.3 0.0018 17.5 0.3 4.2 7 0 0 7 7 7 2 Interferon-related developmental regulator (IFRD) UME PF08064.13 EAX91429.1 - 0.0032 17.3 8.8 10 6.1 0.2 5.4 3 2 0 4 4 4 3 UME (NUC010) domain RTP1_C1 PF10363.9 EAX91429.1 - 0.0085 16.3 0.1 0.47 10.7 0.0 3.8 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1320 PF07030.12 EAX91429.1 - 0.1 12.7 0.1 5.2 7.2 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1320) CLASP_N PF12348.8 EAX91429.1 - 6.8 6.2 13.6 3.5 7.1 0.4 4.1 5 1 0 5 5 5 0 CLASP N terminal DUF4107 PF13389.6 EAX91431.1 - 1.8e-61 207.0 12.5 1e-59 201.3 12.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) P22_AR_C PF10548.9 EAX91433.1 - 0.1 12.8 0.1 26 5.1 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain TMP PF05017.14 EAX91434.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91435.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-binding PF00249.31 EAX91436.1 - 1.6e-19 69.8 0.3 4.3e-09 36.4 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91436.1 - 1.3e-14 54.2 5.8 1.3e-08 35.0 1.6 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX91436.1 - 0.0054 16.6 1.0 0.0054 16.6 1.0 2.7 1 1 1 2 2 2 1 Myb DNA-binding like Tricorn_C1 PF14684.6 EAX91436.1 - 0.013 15.5 2.1 0.65 10.1 0.1 3.0 2 2 0 2 2 2 0 Tricorn protease C1 domain SLIDE PF09111.10 EAX91436.1 - 0.051 13.6 2.8 0.28 11.2 1.2 2.4 1 1 1 2 2 2 0 SLIDE DUF1722 PF08349.11 EAX91437.1 - 0.017 15.4 4.5 0.7 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PET PF06297.14 EAX91437.1 - 1.3 9.3 5.2 2.3 8.6 0.7 2.7 2 0 0 2 2 2 0 PET Domain FapA PF03961.13 EAX91437.1 - 1.4 7.4 9.2 0.071 11.7 2.0 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A DAGK_cat PF00781.24 EAX91438.1 - 6.2e-28 96.9 0.0 8.6e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribosomal_L27e PF01777.18 EAX91439.1 - 2.4e-21 75.9 6.9 3.2e-21 75.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAX91439.1 - 0.0062 16.4 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAX91439.1 - 0.092 12.2 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 ANAPC4_WD40 PF12894.7 EAX91440.1 - 9.2e-09 35.5 0.1 0.25 11.6 0.0 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX91440.1 - 3e-06 27.9 12.6 0.0027 18.5 0.0 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat Methyltr_RsmB-F PF01189.17 EAX91441.1 - 7.9e-39 133.4 0.1 3.9e-38 131.1 0.1 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EAX91441.1 - 0.0028 17.8 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EAX91441.1 - 0.0043 17.7 0.0 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX91441.1 - 0.027 14.3 0.2 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MSV199 PF10553.9 EAX91441.1 - 0.41 10.9 4.2 0.16 12.2 0.3 2.3 2 0 0 2 2 2 0 MSV199 domain Metallophos PF00149.28 EAX91442.1 - 4.4e-31 109.0 0.4 5.7e-31 108.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX91442.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DEAD PF00270.29 EAX91443.1 - 2.1e-38 131.8 0.2 3.5e-38 131.1 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX91443.1 - 5.4e-27 94.3 1.3 1.1e-25 90.2 0.5 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX91443.1 - 2.4e-06 27.7 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAX91443.1 - 0.0058 16.4 0.0 0.036 13.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 EAX91443.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EAX91443.1 - 0.1 12.9 0.1 0.28 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Histone PF00125.24 EAX91444.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX91444.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX91444.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX91444.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Histone PF00125.24 EAX91445.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX91445.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX91445.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myb_DNA-binding PF00249.31 EAX91446.1 - 8.7e-25 86.7 3.2 5.4e-14 52.1 0.4 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91446.1 - 9.6e-22 77.0 6.9 5.7e-13 48.9 0.9 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91446.1 - 1.9e-08 34.3 1.7 0.0025 17.8 0.0 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91446.1 - 3e-05 23.8 0.2 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX91446.1 - 5.1e-05 23.4 0.4 0.0001 22.4 0.4 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DAO_C PF16901.5 EAX91446.1 - 0.012 15.5 0.0 4.9 7.0 0.0 2.1 1 1 1 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase DUF1825 PF08855.10 EAX91446.1 - 0.036 14.0 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Myb_DNA-bind_4 PF13837.6 EAX91446.1 - 0.039 14.3 3.8 0.66 10.4 1.1 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SnAPC_2_like PF11035.8 EAX91446.1 - 0.058 13.5 0.6 0.089 12.9 0.6 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Rap1_C PF11626.8 EAX91446.1 - 0.11 12.6 0.5 0.19 11.8 0.5 1.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4108 PF13390.6 EAX91447.1 - 4.1e-61 205.1 7.9 4.6e-61 204.9 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX91449.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX91449.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX91449.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX91449.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91449.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX91449.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX91449.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX91449.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX91449.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX91449.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX91449.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX91449.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX91450.1 - 3.4e-07 30.7 0.2 6.2e-07 29.9 0.2 1.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX91450.1 - 0.14 12.8 0.5 0.45 11.2 0.5 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Trypan_PARP PF05887.11 EAX91451.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91451.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX91452.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91452.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain EphA2_TM PF14575.6 EAX91455.1 - 0.012 16.5 0.2 0.05 14.5 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EAX91455.1 - 0.019 14.7 0.2 0.035 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Protocadherin PF08374.11 EAX91455.1 - 0.03 14.3 0.3 0.055 13.4 0.3 1.5 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.20 EAX91455.1 - 0.058 13.3 1.3 0.17 11.8 1.3 1.7 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EAX91455.1 - 0.085 12.8 10.7 0.02 14.8 6.6 2.1 2 1 0 2 2 2 0 TMEM154 protein family ECSCR PF15820.5 EAX91455.1 - 1.1 9.2 5.9 0.21 11.5 0.9 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator TraD_N PF12615.8 EAX91455.1 - 1.5 9.6 5.6 18 6.2 0.3 3.3 3 2 0 3 3 3 0 F sex factor protein N terminal CAP PF00188.26 EAX91456.1 - 0.00058 20.7 0.0 0.00092 20.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MKT1_C PF12246.8 EAX91456.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Flavodoxin_1 PF00258.25 EAX91457.1 - 1.2e-23 83.9 0.0 1.3e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EAX91457.1 - 0.0043 17.3 0.0 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain RNA_pol_L PF01193.24 EAX91458.1 - 0.094 12.2 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ank_4 PF13637.6 EAX91459.1 - 5e-59 196.0 16.6 1e-13 51.5 0.1 7.3 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX91459.1 - 3.1e-46 153.9 14.5 5.1e-08 33.0 0.1 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAX91459.1 - 4.1e-41 134.2 14.8 5.3e-07 29.5 0.1 7.5 8 0 0 8 8 7 6 Ankyrin repeat Ank_2 PF12796.7 EAX91459.1 - 1.5e-40 137.6 17.8 1.2e-13 51.5 0.5 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91459.1 - 1.7e-30 104.7 20.8 1e-08 35.3 0.1 5.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91459.1 - 1.8e-16 59.9 2.7 1.8e-16 59.9 2.7 3.1 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX91459.1 - 3e-05 24.1 3.7 5.6 7.2 0.0 5.9 3 3 4 7 7 7 1 Protein of unknown function (DUF3718) PH_8 PF15409.6 EAX91459.1 - 0.0011 19.2 1.2 8.1 6.8 0.0 4.1 1 1 4 5 5 5 1 Pleckstrin homology domain Shigella_OspC PF06128.11 EAX91459.1 - 0.0022 17.8 1.8 1.9 8.2 0.0 3.3 1 1 1 3 3 3 2 Shigella flexneri OspC protein CEP44 PF15007.6 EAX91459.1 - 0.048 13.8 4.4 14 5.9 0.0 4.4 3 1 1 5 5 5 0 Centrosomal spindle body, CEP44 AnkUBD PF18418.1 EAX91459.1 - 0.068 13.3 0.1 1.3 9.2 0.0 2.6 2 1 1 3 3 3 0 Ankyrin ubiquitin-binding domain Clathrin PF00637.20 EAX91459.1 - 0.91 9.4 5.8 13 5.7 0.0 4.0 3 2 2 5 5 5 0 Region in Clathrin and VPS LRR_5 PF13306.6 EAX91460.1 - 3.4e-76 253.3 36.4 3.3e-23 82.0 9.0 5.0 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91460.1 - 2e-15 56.3 0.0 0.035 13.9 0.0 6.4 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EAX91460.1 - 1e-08 35.3 0.1 0.46 11.0 0.1 6.5 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX91461.1 - 7.2e-36 123.0 24.0 3.1e-20 72.4 8.8 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91461.1 - 8.5e-09 35.1 0.0 1.5e-05 24.7 0.0 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EAX91461.1 - 0.0083 16.5 0.1 1.2 9.7 0.0 3.9 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) ATG7_N PF16420.5 EAX91463.1 - 0.013 15.2 0.3 0.023 14.3 0.1 1.5 2 0 0 2 2 2 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF3621 PF12285.8 EAX91463.1 - 0.35 11.3 5.4 0.36 11.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3621) UBX PF00789.20 EAX91464.1 - 0.012 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 UBX domain PQ-loop PF04193.14 EAX91465.1 - 1.3e-19 69.7 11.8 3.5e-12 45.9 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF2970 PF11174.8 EAX91465.1 - 0.11 12.4 0.6 0.11 12.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF5418 PF17439.2 EAX91465.1 - 2.2 8.4 9.0 0.25 11.4 1.9 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5418) DUF4407 PF14362.6 EAX91466.1 - 0.012 15.0 0.6 0.014 14.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 EAX91466.1 - 0.037 14.4 4.6 2.8 8.4 0.1 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SNCAIP_SNCA_bd PF16700.5 EAX91466.1 - 0.042 13.6 1.2 1.4 8.7 0.0 3.3 3 1 0 4 4 4 0 Synphilin-1 alpha-Synuclein-binding domain ABC_tran_CTD PF16326.5 EAX91466.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.6 3 1 0 3 3 3 0 ABC transporter C-terminal domain SlyX PF04102.12 EAX91466.1 - 0.28 11.8 7.9 5.3 7.7 0.2 3.4 3 0 0 3 3 3 0 SlyX DUF3552 PF12072.8 EAX91466.1 - 0.72 9.2 7.2 0.29 10.5 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF16 PF01519.16 EAX91466.1 - 1.6 9.2 9.6 76 3.9 9.6 2.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 YabA PF06156.13 EAX91466.1 - 2.2 9.0 6.5 0.79 10.4 2.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 EAX91467.1 - 3.4e-31 108.6 0.0 6.9e-31 107.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91467.1 - 1.7e-17 63.5 0.0 4e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91467.1 - 0.00044 19.7 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like COMPASS-Shg1 PF05205.12 EAX91467.1 - 0.19 12.4 0.4 19 6.0 0.1 2.5 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Ank_2 PF12796.7 EAX91469.1 - 1.6e-46 156.8 10.2 2.5e-16 60.0 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91469.1 - 8.7e-41 137.8 2.6 7.9e-13 48.6 0.0 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX91469.1 - 4.5e-39 132.0 4.7 5.5e-12 45.7 0.0 7.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91469.1 - 1.3e-31 105.0 2.4 0.00084 19.6 0.0 8.1 8 0 0 8 8 7 6 Ankyrin repeat Ank PF00023.30 EAX91469.1 - 4.4e-30 102.8 0.1 2.3e-05 24.6 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat DUF812 PF05667.11 EAX91469.1 - 1e-05 24.6 4.2 1.5e-05 24.2 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ADIP PF11559.8 EAX91469.1 - 1.6e-05 25.0 6.4 5.1e-05 23.4 6.4 1.9 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 EAX91469.1 - 2e-05 24.6 8.2 4.5e-05 23.4 8.2 1.6 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 EAX91469.1 - 0.00015 21.7 5.0 0.00025 20.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) bZIP_1 PF00170.21 EAX91469.1 - 0.00018 21.5 3.8 0.00063 19.8 3.8 2.1 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 EAX91469.1 - 0.00049 20.4 9.2 0.0042 17.4 3.7 3.4 2 1 1 3 3 2 1 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 EAX91469.1 - 0.00057 20.1 2.4 0.0013 19.0 2.4 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 EAX91469.1 - 0.00067 19.4 2.2 0.0011 18.7 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) BicD PF09730.9 EAX91469.1 - 0.00068 18.2 2.7 0.00092 17.8 2.7 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D APG6_N PF17675.1 EAX91469.1 - 0.00069 20.2 3.2 0.0019 18.7 3.2 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region AAA_13 PF13166.6 EAX91469.1 - 0.0014 17.3 10.6 0.0018 17.0 10.6 1.1 1 0 0 1 1 1 1 AAA domain DUF2730 PF10805.8 EAX91469.1 - 0.002 18.2 0.4 0.0042 17.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF16 PF01519.16 EAX91469.1 - 0.0022 18.5 4.2 0.0022 18.5 4.2 1.9 2 0 0 2 2 1 1 Protein of unknown function DUF16 Phlebovirus_NSM PF07246.11 EAX91469.1 - 0.0022 17.4 0.5 0.0038 16.6 0.5 1.4 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Golgin_A5 PF09787.9 EAX91469.1 - 0.0029 17.1 2.1 0.0044 16.5 2.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Occludin_ELL PF07303.13 EAX91469.1 - 0.0031 18.2 2.1 0.014 16.1 2.1 2.1 1 0 0 1 1 1 1 Occludin homology domain Fez1 PF06818.15 EAX91469.1 - 0.0034 17.9 1.1 0.0075 16.7 0.9 1.6 2 0 0 2 2 1 1 Fez1 Spc7 PF08317.11 EAX91469.1 - 0.0034 16.3 5.0 0.0053 15.7 5.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4472 PF14739.6 EAX91469.1 - 0.0038 17.9 2.7 0.0088 16.8 2.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) ZapB PF06005.12 EAX91469.1 - 0.0048 17.3 9.8 0.013 15.9 9.8 1.8 1 0 0 1 1 1 1 Cell division protein ZapB Uso1_p115_C PF04871.13 EAX91469.1 - 0.0052 17.2 1.7 0.012 15.9 1.7 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Ax_dynein_light PF10211.9 EAX91469.1 - 0.0052 16.7 2.6 0.0052 16.7 2.6 1.8 2 0 0 2 2 1 1 Axonemal dynein light chain HMMR_C PF15908.5 EAX91469.1 - 0.0057 16.9 4.0 0.013 15.8 4.0 1.6 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal TPR_MLP1_2 PF07926.12 EAX91469.1 - 0.0059 16.7 8.7 0.013 15.6 8.7 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4686 PF15742.5 EAX91469.1 - 0.0063 15.7 3.8 0.0063 15.7 3.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) ATG16 PF08614.11 EAX91469.1 - 0.007 16.6 3.8 0.011 15.9 3.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 EAX91469.1 - 0.011 15.1 5.6 0.023 14.0 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CorA PF01544.18 EAX91469.1 - 0.011 15.1 2.5 0.018 14.3 1.0 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Nup54 PF13874.6 EAX91469.1 - 0.011 15.9 0.7 0.021 14.9 0.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ERM PF00769.19 EAX91469.1 - 0.011 15.6 0.7 0.02 14.7 0.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GrpE PF01025.19 EAX91469.1 - 0.011 15.4 2.7 0.011 15.4 2.7 2.5 2 0 0 2 2 2 0 GrpE FlaC_arch PF05377.11 EAX91469.1 - 0.011 16.1 7.6 0.023 15.1 3.7 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EAX91469.1 - 0.011 15.8 3.7 0.023 14.8 3.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EAX91469.1 - 0.013 15.5 4.0 0.026 14.5 4.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EAX91469.1 - 0.014 15.6 6.9 0.038 14.2 6.9 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 EAX91469.1 - 0.015 15.6 2.7 0.025 14.9 2.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pox_A_type_inc PF04508.12 EAX91469.1 - 0.016 15.0 0.4 0.96 9.4 0.1 3.0 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat HAP1_N PF04849.13 EAX91469.1 - 0.016 14.4 3.5 0.029 13.6 3.5 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Tup_N PF08581.10 EAX91469.1 - 0.017 15.4 6.3 0.017 15.4 6.3 2.5 2 1 0 2 2 1 0 Tup N-terminal Csm1_N PF18504.1 EAX91469.1 - 0.02 15.2 7.8 0.79 10.1 1.6 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain zf-C4H2 PF10146.9 EAX91469.1 - 0.025 14.9 2.0 0.045 14.1 2.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Jnk-SapK_ap_N PF09744.9 EAX91469.1 - 0.03 14.6 3.7 0.063 13.5 3.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EAX91469.1 - 0.031 13.4 5.0 0.049 12.7 5.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AKNA PF12443.8 EAX91469.1 - 0.044 14.4 1.2 0.16 12.7 1.1 1.9 1 1 1 2 2 1 0 AT-hook-containing transcription factor CENP-H PF05837.12 EAX91469.1 - 0.049 14.1 3.3 0.13 12.7 3.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 EAX91469.1 - 0.059 13.8 8.4 0.9 10.0 8.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 EAX91469.1 - 0.077 13.1 7.8 0.072 13.2 5.2 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 EAX91469.1 - 0.085 12.2 5.6 0.15 11.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 EAX91469.1 - 0.085 12.5 6.6 0.18 11.5 6.6 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease PspA_IM30 PF04012.12 EAX91469.1 - 0.098 12.2 2.3 0.22 11.0 2.2 1.6 1 1 0 1 1 1 0 PspA/IM30 family TAF6_C PF07571.13 EAX91469.1 - 0.12 12.7 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 1 0 TAF6 C-terminal HEAT repeat domain FeThRed_B PF02943.15 EAX91469.1 - 0.12 12.4 2.5 0.088 12.8 0.5 1.8 2 0 0 2 2 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Lipoprotein_20 PF13942.6 EAX91469.1 - 0.13 12.2 1.6 0.2 11.5 1.6 1.3 1 0 0 1 1 1 0 YfhG lipoprotein YabA PF06156.13 EAX91469.1 - 0.13 12.9 6.3 0.052 14.2 3.1 2.1 2 0 0 2 2 1 0 Initiation control protein YabA GIT_CC PF16559.5 EAX91469.1 - 0.14 12.0 9.7 0.84 9.5 8.6 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HemX PF04375.14 EAX91469.1 - 0.15 11.3 4.7 0.25 10.6 4.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase USP8_interact PF08941.10 EAX91469.1 - 0.16 11.8 3.8 0.36 10.6 3.8 1.7 1 1 0 1 1 1 0 USP8 interacting Mod_r PF07200.13 EAX91469.1 - 0.17 12.0 7.0 0.37 10.9 7.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein LPP PF04728.13 EAX91469.1 - 0.19 12.1 5.4 0.21 12.0 1.7 2.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Exonuc_VII_L PF02601.15 EAX91469.1 - 0.25 10.9 1.9 0.34 10.4 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 EAX91469.1 - 0.3 10.9 11.1 0.24 11.2 6.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.11 EAX91469.1 - 0.38 11.0 9.7 0.33 11.2 6.6 2.5 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 Sec34 PF04136.15 EAX91469.1 - 0.47 10.3 10.6 0.24 11.3 4.5 2.3 2 0 0 2 2 2 0 Sec34-like family CLZ PF16526.5 EAX91469.1 - 0.49 10.8 2.9 4.5 7.7 2.9 2.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EAX91469.1 - 0.54 10.3 4.0 1.6 8.8 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Dzip-like_N PF13815.6 EAX91469.1 - 0.61 10.1 4.1 0.33 10.9 1.3 2.0 2 0 0 2 2 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ABC_tran_CTD PF16326.5 EAX91469.1 - 0.64 10.3 4.0 3.9 7.8 3.6 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain TSNAXIP1_N PF15739.5 EAX91469.1 - 0.64 10.4 10.7 8.8 6.8 10.4 2.5 1 1 1 2 2 1 0 Translin-associated factor X-interacting N-terminus bZIP_2 PF07716.15 EAX91469.1 - 0.71 10.0 8.1 0.23 11.6 2.5 2.5 1 1 2 3 3 3 0 Basic region leucine zipper Laminin_II PF06009.12 EAX91469.1 - 0.75 9.8 8.4 1 9.4 6.9 1.9 1 1 1 2 2 2 0 Laminin Domain II DivIVA PF05103.13 EAX91469.1 - 0.75 9.9 8.7 1.5 8.9 5.5 2.4 1 1 1 2 2 2 0 DivIVA protein Fungal_TACC PF12709.7 EAX91469.1 - 1 9.8 9.1 3.8 8.0 6.6 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins BLOC1_2 PF10046.9 EAX91469.1 - 1.6 9.1 23.2 3.7 7.9 2.1 3.7 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 She9_MDM33 PF05546.11 EAX91469.1 - 1.8 8.3 8.1 3.9 7.2 7.2 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family DUF2935 PF11155.8 EAX91469.1 - 3 8.2 8.9 5.5 7.4 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Syntaxin-6_N PF09177.11 EAX91469.1 - 3.4 8.3 6.4 7.4 7.2 5.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 EAX91469.1 - 3.9 7.7 13.5 5.4 7.2 2.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EAX91469.1 - 5.4 7.1 16.8 0.81 9.7 10.2 3.1 4 1 1 5 5 2 0 TATA element modulatory factor 1 DNA binding Sec8_exocyst PF04048.14 EAX91469.1 - 5.7 6.8 11.6 9.8 6.1 10.1 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF4200 PF13863.6 EAX91470.1 - 3.1e-15 56.6 17.1 3.1e-15 56.6 17.1 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 EAX91470.1 - 1.1 9.3 8.7 0.14 12.2 3.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EAX91470.1 - 2.1 7.6 46.9 0.053 12.8 4.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) HisKA PF00512.25 EAX91470.1 - 5.4 7.1 7.4 0.59 10.2 0.7 3.1 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF1810 PF08837.11 EAX91472.1 - 0.045 13.6 0.6 0.068 13.0 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1810) DUF2909 PF11137.8 EAX91473.1 - 0.015 15.2 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Gram_pos_anchor PF00746.21 EAX91473.1 - 0.066 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_S8 PF00082.22 EAX91474.1 - 3.6e-14 52.7 2.8 7.8e-14 51.6 2.7 1.6 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAX91474.1 - 0.001 19.0 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain P22_portal PF16510.5 EAX91474.1 - 0.062 11.9 0.1 0.087 11.4 0.1 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein CBM_35 PF16990.5 EAX91474.1 - 0.21 11.9 1.4 0.7 10.2 0.1 2.6 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) RasGAP_C PF03836.15 EAX91475.1 - 0.0041 17.3 1.3 0.011 15.8 0.7 2.1 1 1 1 2 2 2 1 RasGAP C-terminus PC4 PF02229.16 EAX91475.1 - 0.092 12.4 1.0 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) V-SNARE_C PF12352.8 EAX91475.1 - 0.11 12.9 2.1 41 4.6 0.0 4.0 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Baculo_PEP_C PF04513.12 EAX91475.1 - 0.34 11.0 4.7 1.1 9.3 0.9 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.8 EAX91475.1 - 0.81 10.0 4.4 4.6 7.6 4.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.12 EAX91476.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX91476.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX91476.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family FliJ PF02050.16 EAX91477.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Sulf_coat_C PF12193.8 EAX91478.1 - 1.4e-09 37.8 0.8 8.2 6.6 0.0 5.2 5 0 0 5 5 5 5 Sulfolobus virus coat protein C terminal AbiEi_3_N PF17194.4 EAX91478.1 - 6.8e-07 29.2 0.0 40 4.3 0.0 5.5 6 0 0 6 6 6 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Sec61_beta PF03911.16 EAX91478.1 - 1.9e-05 24.6 1.0 30 4.7 0.0 4.7 5 0 0 5 5 5 0 Sec61beta family VP4_haemagglut PF00426.18 EAX91478.1 - 3.8e-05 24.0 3.3 34 4.6 0.0 5.0 1 1 4 5 5 5 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain EMC3_TMCO1 PF01956.16 EAX91478.1 - 0.00045 20.0 2.7 16 5.2 0.1 4.6 1 1 3 4 4 4 1 Integral membrane protein EMC3/TMCO1-like YidC_periplas PF14849.6 EAX91478.1 - 0.0017 18.3 0.0 1.3e+02 2.3 0.0 4.7 5 0 0 5 5 5 0 YidC periplasmic domain PTCB-BRCT PF12738.7 EAX91478.1 - 0.0048 16.8 0.6 3.2e+02 1.4 0.0 5.5 6 0 0 6 6 6 0 twin BRCT domain MYT1 PF08474.11 EAX91478.1 - 0.031 14.2 0.0 3.2e+02 1.1 0.0 4.8 6 0 0 6 6 6 0 Myelin transcription factor 1 DUF220 PF02713.14 EAX91478.1 - 0.041 14.0 5.2 1.3e+02 2.8 0.0 4.7 2 1 1 5 5 5 0 Domain of unknown function DUF220 E3_binding PF02817.17 EAX91478.1 - 0.09 13.1 4.7 4.3e+02 1.4 0.0 5.8 6 0 0 6 6 6 0 e3 binding domain Ank_2 PF12796.7 EAX91479.1 - 5.3e-08 33.3 0.1 0.00054 20.5 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91479.1 - 2.8e-05 24.6 0.1 1.1 10.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91479.1 - 0.00012 22.2 0.0 4.1 8.3 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 EAX91479.1 - 0.0016 18.4 1.3 0.0016 18.4 1.3 2.7 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) SurA_N PF09312.11 EAX91479.1 - 0.052 13.6 0.2 0.17 11.9 0.2 1.8 1 1 0 1 1 1 0 SurA N-terminal domain Ank PF00023.30 EAX91479.1 - 0.078 13.5 0.0 40 4.9 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EAX91479.1 - 0.18 12.2 0.0 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ubiquitin PF00240.23 EAX91480.1 - 1.6e-31 107.8 0.7 1e-22 79.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX91480.1 - 4.1e-13 49.0 0.1 7.7e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX91480.1 - 0.0012 19.2 0.1 0.65 10.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 EAX91480.1 - 0.0086 16.6 0.0 7.6 7.2 0.0 2.4 2 0 0 2 2 2 2 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX91480.1 - 0.015 15.3 0.0 7.8 6.6 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like GABP-alpha PF11620.8 EAX91480.1 - 0.09 13.0 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 GA-binding protein alpha chain Ribosomal_60s PF00428.19 EAX91481.1 - 1.9e-14 54.0 14.8 2.4e-14 53.7 14.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1456 PF07308.13 EAX91481.1 - 0.055 13.8 0.2 0.081 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DUF1687 PF07955.11 EAX91481.1 - 0.061 13.8 0.1 0.076 13.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) DUF3879 PF12995.7 EAX91481.1 - 0.077 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) ABC_tran_CTD PF16326.5 EAX91482.1 - 0.011 15.9 12.2 0.88 9.9 0.1 3.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain Tape_meas_lam_C PF09718.10 EAX91482.1 - 0.093 12.9 0.3 0.31 11.2 0.3 1.9 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Apolipoprotein PF01442.18 EAX91482.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EAX91482.1 - 0.58 10.2 9.7 12 5.9 1.7 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 EAX91482.1 - 2.1 8.5 9.6 1.9 8.6 0.1 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF2730) Thioredoxin_6 PF13848.6 EAX91483.1 - 2.6e-05 24.2 0.3 0.21 11.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain D123 PF07065.14 EAX91484.1 - 2e-42 145.4 1.9 8.6e-38 130.2 0.5 2.2 1 1 1 2 2 2 2 D123 Ank_2 PF12796.7 EAX91485.1 - 5.3e-106 347.4 47.2 8.5e-16 58.3 1.6 11.2 2 1 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91485.1 - 7.1e-95 307.7 39.7 3.6e-06 27.2 0.1 19.8 20 0 0 20 20 20 17 Ankyrin repeat Ank_4 PF13637.6 EAX91485.1 - 1.5e-94 309.2 39.2 1.6e-08 34.9 0.1 18.3 6 4 11 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91485.1 - 2.9e-80 254.6 42.6 0.00012 22.3 0.0 20.9 22 0 0 22 22 22 18 Ankyrin repeat Ank_5 PF13857.6 EAX91485.1 - 1.2e-72 239.0 29.6 4.3e-11 42.8 0.0 14.6 5 3 11 17 17 17 14 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91485.1 - 2.3e-38 130.0 58.0 1.7e-37 127.2 6.6 9.0 5 3 4 10 10 10 3 Domain of unknown function (DUF3447) DUF3895 PF13034.6 EAX91485.1 - 1.3 9.1 7.5 9.7 6.3 0.1 5.1 5 1 1 6 6 6 0 Protein of unknown function (DUF3895) DUF3718 PF12514.8 EAX91485.1 - 2.7 8.2 6.3 24 5.2 0.0 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3718) DUF573 PF04504.14 EAX91486.1 - 0.15 12.7 8.7 0.94 10.2 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 UPF0242 PF06785.11 EAX91486.1 - 2.4 8.2 17.6 0.24 11.5 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 EAX91486.1 - 5.7 7.1 9.6 39 4.4 9.6 2.2 1 1 0 1 1 1 0 Up-regulated During Septation RNA_pol_Rpb2_1 PF04563.15 EAX91488.1 - 9 5.7 9.8 1.7 8.1 5.6 1.9 1 1 1 2 2 2 0 RNA polymerase beta subunit zf-C2H2_assoc2 PF16624.5 EAX91489.1 - 0.0029 18.6 1.1 0.0032 18.4 1.1 1.1 1 0 0 1 1 1 1 Unstructured region upstream of a zinc-finger NEMP PF10225.9 EAX91489.1 - 0.53 9.9 1.2 0.57 9.8 1.2 1.0 1 0 0 1 1 1 0 NEMP family DDE_Tnp_ISL3 PF01610.17 EAX91490.1 - 0.00025 20.8 0.6 0.00038 20.3 0.1 1.5 2 0 0 2 2 2 1 Transposase WASH-7_C PF14746.6 EAX91491.1 - 0.034 13.8 4.9 0.13 11.9 1.1 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Pox_Ag35 PF03286.14 EAX91491.1 - 0.63 9.8 5.3 1 9.1 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MCM6_C PF18263.1 EAX91491.1 - 2.8 8.2 9.2 0.85 9.9 5.6 2.0 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain LRR_9 PF14580.6 EAX91494.1 - 0.0011 18.5 1.1 0.0024 17.4 1.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAX91494.1 - 0.042 13.6 3.8 0.19 11.5 3.7 2.2 1 1 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 EAX91494.1 - 2.5 8.6 15.5 0.11 13.0 7.8 2.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Pep1_7 PF17232.2 EAX91495.1 - 0.073 13.5 4.3 1 9.9 0.0 3.0 3 0 0 3 3 3 0 Elicitor peptide 1-7 Ly49 PF08391.10 EAX91495.1 - 8.2 6.8 11.7 0.83 10.0 6.6 1.9 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region GOLGA2L5 PF15070.6 EAX91497.1 - 0.00022 20.0 14.6 0.00027 19.7 14.6 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 PEP-utilisers_N PF05524.13 EAX91497.1 - 0.0017 18.5 5.4 0.0017 18.5 5.4 2.1 1 1 1 2 2 2 1 PEP-utilising enzyme, N-terminal V_ATPase_I PF01496.19 EAX91497.1 - 0.0056 14.7 6.5 0.0052 14.8 6.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.19 EAX91497.1 - 0.015 15.1 23.2 0.019 14.8 23.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CpxA_peri PF16527.5 EAX91497.1 - 0.016 15.6 1.6 0.016 15.6 1.6 2.5 1 1 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain DUF812 PF05667.11 EAX91497.1 - 0.11 11.4 20.8 0.19 10.5 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Nre_C PF04895.12 EAX91497.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.9 2 1 1 3 3 3 0 Archaeal Nre, C-terminal Amidase PF01425.21 EAX91497.1 - 0.87 8.5 2.3 1 8.2 2.3 1.1 1 0 0 1 1 1 0 Amidase Ntox1 PF15500.6 EAX91497.1 - 0.97 9.8 6.6 1.2 9.5 4.3 2.2 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF4200 PF13863.6 EAX91497.1 - 1.7 9.1 33.2 9.6 6.6 33.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 EAX91497.1 - 3.2 7.0 16.2 4.1 6.7 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) I_LWEQ PF01608.17 EAX91497.1 - 3.4 7.9 21.9 1.7 8.8 3.8 2.1 1 1 1 2 2 2 0 I/LWEQ domain Golgin_A5 PF09787.9 EAX91497.1 - 3.7 6.9 25.5 7.3 6.0 25.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 EAX91497.1 - 4.5 6.7 13.6 5.9 6.4 13.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Radial_spoke_3 PF06098.11 EAX91498.1 - 0.087 12.1 13.8 0.091 12.0 13.8 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 HSP70 PF00012.20 EAX91498.1 - 6.5 4.8 8.9 6.6 4.8 8.9 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF3447 PF11929.8 EAX91499.1 - 1.1e-05 25.3 0.6 1.1e-05 25.3 0.6 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX91499.1 - 0.01 16.3 0.8 2.7 8.8 0.1 4.6 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EAX91499.1 - 0.011 16.3 0.1 0.62 10.7 0.1 3.4 3 1 1 4 4 4 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91499.1 - 0.099 13.3 0.1 3.8 8.2 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DegQ PF08181.11 EAX91501.1 - 0.031 14.4 2.3 0.041 14.0 1.4 1.7 1 1 1 2 2 2 0 DegQ (SacQ) family CCDC-167 PF15188.6 EAX91503.1 - 0.0029 17.9 0.1 0.0034 17.7 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 CorA PF01544.18 EAX91503.1 - 0.027 13.8 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF919 PF06034.11 EAX91504.1 - 0.062 13.1 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TALPID3 PF15324.6 EAX91506.1 - 0.073 10.8 0.3 0.081 10.6 0.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target FAS_N PF17828.1 EAX91509.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX91509.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX91510.1 - 0.026 14.9 0.7 0.038 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX91510.1 - 1.9 7.5 4.1 2 7.4 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX91510.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX91510.1 - 7.8 6.5 7.5 8.3 6.4 7.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX91511.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX91511.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EF-hand_10 PF14788.6 EAX91514.1 - 0.0012 18.7 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 EF hand EMP70 PF02990.16 EAX91515.1 - 6.8e-87 292.3 19.3 1e-86 291.7 19.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Flo11 PF10182.9 EAX91515.1 - 0.013 15.6 0.1 0.99 9.5 0.0 2.5 1 1 1 2 2 2 0 Flo11 domain MRAP PF15183.6 EAX91515.1 - 0.049 13.6 2.7 0.068 13.1 0.7 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Myc_target_1 PF15179.6 EAX91515.1 - 0.99 9.3 4.3 0.19 11.6 0.2 1.8 2 0 0 2 2 2 0 Myc target protein 1 LSM PF01423.22 EAX91516.1 - 1.2e-14 53.7 0.0 1.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain zf-B_box PF00643.24 EAX91517.1 - 1.7e-09 37.7 4.4 1.7e-09 37.7 4.4 2.8 3 0 0 3 3 3 1 B-box zinc finger zf-C3HC4_3 PF13920.6 EAX91517.1 - 2e-05 24.4 6.8 2e-05 24.4 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX91517.1 - 4e-05 23.9 8.0 4e-05 23.9 8.0 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EAX91517.1 - 0.0012 18.6 5.8 0.0012 18.6 5.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF5617 PF18493.1 EAX91517.1 - 0.0094 16.0 1.3 2.2 8.4 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF5617) DUF3825 PF12873.7 EAX91517.1 - 0.02 14.4 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) zf-RING_5 PF14634.6 EAX91517.1 - 0.029 14.3 7.5 0.029 14.3 7.5 2.5 2 1 0 2 2 2 0 zinc-RING finger domain MtaB PF12176.8 EAX91517.1 - 0.087 11.6 3.5 0.39 9.4 1.7 2.1 1 1 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit DUF3150 PF11348.8 EAX91517.1 - 0.092 12.0 4.6 0.15 11.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Exonuc_VII_L PF02601.15 EAX91517.1 - 1.1 8.7 6.6 0.33 10.5 1.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Zn_ribbon_17 PF17120.5 EAX91517.1 - 6.3 6.5 14.8 0.54 9.9 6.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EAX91517.1 - 7.4 6.5 17.0 0.11 12.4 8.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.12 EAX91517.1 - 9.3 6.3 9.7 1.7 8.7 0.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF383 PF04063.14 EAX91519.1 - 4.6e-21 75.4 1.6 4.8e-20 72.0 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EAX91519.1 - 0.001 18.9 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_EZ PF13513.6 EAX91519.1 - 0.0072 16.8 0.0 0.077 13.5 0.0 2.5 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 EAX91519.1 - 0.025 14.8 0.0 0.77 10.2 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.23 EAX91519.1 - 0.096 12.8 0.6 51 4.1 0.1 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EAX91519.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats NuDC PF16273.5 EAX91519.1 - 0.12 13.0 0.5 0.12 13.0 0.5 1.6 2 0 0 2 2 2 0 Nuclear distribution C domain Ank_2 PF12796.7 EAX91520.1 - 1.6e-42 144.0 3.7 9.2e-18 64.6 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91520.1 - 2.5e-28 98.1 3.2 1.6e-09 38.1 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91520.1 - 3.9e-22 76.0 0.5 0.0023 18.3 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX91520.1 - 7.6e-22 77.1 2.4 7.4e-06 26.2 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX91520.1 - 2.8e-17 62.3 0.1 0.0012 19.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Spore_Cse60 PF10957.8 EAX91520.1 - 0.015 15.3 0.3 1.5 8.9 0.0 3.7 2 2 2 4 4 4 0 Sporulation protein Cse60 DUF4988 PF16378.5 EAX91520.1 - 0.095 12.4 1.6 0.17 11.6 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function FlaC_arch PF05377.11 EAX91520.1 - 0.23 11.9 3.1 0.45 10.9 1.6 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) LRR_6 PF13516.6 EAX91521.1 - 4.2e-18 63.8 19.3 0.056 13.5 0.1 10.6 11 0 0 11 11 11 5 Leucine Rich repeat LRR_1 PF00560.33 EAX91521.1 - 6.5e-07 29.0 13.1 0.38 11.5 0.1 8.9 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_4 PF12799.7 EAX91521.1 - 1.3e-05 25.4 20.4 0.0023 18.3 0.4 7.0 6 2 1 7 7 6 1 Leucine Rich repeats (2 copies) Spectrin_like PF18373.1 EAX91521.1 - 0.017 15.2 8.1 0.15 12.1 1.0 3.0 1 1 1 2 2 2 0 Spectrin like domain LRR_8 PF13855.6 EAX91521.1 - 0.065 13.0 21.6 7.6 6.4 0.7 6.7 4 2 3 7 7 7 0 Leucine rich repeat DUF3391 PF11871.8 EAX91521.1 - 0.12 12.9 3.0 0.29 11.7 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Phe_ZIP PF08916.11 EAX91521.1 - 0.18 12.5 3.3 2.7 8.8 0.1 3.4 3 0 0 3 3 3 0 Phenylalanine zipper IFT57 PF10498.9 EAX91521.1 - 0.32 9.9 22.2 2.1 7.2 22.2 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 EAX91521.1 - 0.5 10.4 12.0 0.096 12.7 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MnmE_helical PF12631.7 EAX91521.1 - 0.8 9.8 8.4 2.2 8.4 8.4 1.8 1 0 0 1 1 1 0 MnmE helical domain Latarcin PF10279.9 EAX91521.1 - 1.6 9.1 14.5 0.53 10.7 4.2 3.0 1 1 1 2 2 2 0 Latarcin precursor SIMPL PF04402.14 EAX91521.1 - 2.1 8.7 8.0 0.82 10.1 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Sec20 PF03908.13 EAX91521.1 - 4.1 7.4 8.3 0.85 9.6 3.0 2.7 3 0 0 3 3 3 0 Sec20 COG5 PF10392.9 EAX91522.1 - 0.022 14.9 2.9 0.022 14.9 2.9 2.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4574 PF15141.6 EAX91522.1 - 0.064 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ank_2 PF12796.7 EAX91523.1 - 1.7e-36 124.6 10.8 3.6e-16 59.5 0.5 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX91523.1 - 5.2e-35 119.2 3.6 5.2e-35 119.2 3.6 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX91523.1 - 7.9e-20 71.0 6.8 3.4e-10 40.2 0.1 6.1 2 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91523.1 - 1.4e-19 69.5 2.4 3.5e-07 30.4 0.0 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX91523.1 - 1.2e-18 65.2 5.5 1.2e-05 25.3 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX91523.1 - 1.2e-13 51.0 5.9 3.3e-07 30.5 0.3 4.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Gly_rich PF12810.7 EAX91524.1 - 1.1e-18 68.1 8.4 1.2e-18 67.9 8.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Rogdi_lz PF10259.9 EAX91525.1 - 0.037 13.5 2.4 0.29 10.5 2.3 2.4 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein SAT PF16073.5 EAX91525.1 - 0.099 12.4 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Adaptin_N PF01602.20 EAX91527.1 - 2.1e-57 194.9 0.1 2.7e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX91527.1 - 2.2e-31 109.1 0.5 5.9e-30 104.4 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EAX91527.1 - 3.6e-08 33.5 0.0 7.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain RIX1 PF08167.12 EAX91527.1 - 3.3e-06 27.0 0.5 1.4e-05 24.9 0.1 2.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 EAX91527.1 - 0.00013 21.9 2.3 4.8 7.7 0.1 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EAX91527.1 - 0.0057 17.0 2.9 0.17 12.3 0.0 4.1 2 2 3 5 5 5 2 HEAT repeats Arm PF00514.23 EAX91527.1 - 0.028 14.5 0.7 0.39 10.8 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AP4E_app_platf PF14807.6 EAX91527.1 - 0.03 14.7 0.0 0.089 13.2 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Ank_2 PF12796.7 EAX91528.1 - 1.8e-47 159.8 9.6 6.8e-18 65.0 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91528.1 - 4.4e-33 113.2 0.4 4.3e-08 33.5 0.0 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX91528.1 - 3.2e-30 103.8 3.3 3.3e-08 33.6 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91528.1 - 6.9e-25 84.4 0.7 0.013 15.9 0.0 7.5 8 0 0 8 8 6 4 Ankyrin repeat Ank PF00023.30 EAX91528.1 - 8.5e-25 86.1 0.1 0.0025 18.2 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat EzrA PF06160.12 EAX91528.1 - 2.9e-06 25.8 13.7 4.6e-06 25.1 13.7 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 EAX91528.1 - 5.4e-06 25.5 7.5 1.1e-05 24.5 7.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 EAX91528.1 - 1.3e-05 25.8 6.7 1.3e-05 25.8 6.7 1.6 2 0 0 2 2 1 1 Fez1 HAUS5 PF14817.6 EAX91528.1 - 3.5e-05 22.8 3.8 5e-05 22.3 3.8 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 ATG16 PF08614.11 EAX91528.1 - 3.6e-05 24.1 6.1 7.2e-05 23.1 6.0 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EAX91528.1 - 4.5e-05 22.5 4.8 7.1e-05 21.9 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) BRE1 PF08647.11 EAX91528.1 - 5.2e-05 23.2 14.6 5.2e-05 23.2 14.6 2.4 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase DUF641 PF04859.12 EAX91528.1 - 0.00012 22.4 4.7 0.0003 21.1 4.7 1.7 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) BicD PF09730.9 EAX91528.1 - 0.00012 20.7 5.1 0.00019 20.0 5.1 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D CENP-F_leu_zip PF10473.9 EAX91528.1 - 0.00021 21.3 8.1 0.00047 20.2 8.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 EAX91528.1 - 0.00025 21.1 2.2 0.00039 20.4 2.2 1.3 1 0 0 1 1 1 1 JAKMIP CC3 domain zf-C4H2 PF10146.9 EAX91528.1 - 0.00037 20.9 6.6 0.00037 20.9 6.6 1.7 2 0 0 2 2 1 1 Zinc finger-containing protein APG6_N PF17675.1 EAX91528.1 - 0.0004 20.9 10.0 0.0004 20.9 10.0 2.3 2 1 1 3 3 2 1 Apg6 coiled-coil region TSC22 PF01166.18 EAX91528.1 - 0.00059 20.1 16.9 0.0042 17.4 1.6 4.0 2 1 2 4 4 3 2 TSC-22/dip/bun family KASH_CCD PF14662.6 EAX91528.1 - 0.0006 19.7 33.8 0.0033 17.3 12.3 2.1 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 EAX91528.1 - 0.00072 18.7 10.4 0.0011 18.1 10.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EAX91528.1 - 0.00097 19.4 7.6 0.00097 19.4 7.6 1.6 2 0 0 2 2 1 1 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 EAX91528.1 - 0.0011 19.1 8.2 0.0013 18.9 5.1 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EAX91528.1 - 0.0015 18.6 3.5 0.0031 17.5 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) LPP PF04728.13 EAX91528.1 - 0.0016 18.8 9.5 0.0073 16.7 1.4 3.6 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Laminin_I PF06008.14 EAX91528.1 - 0.0019 18.0 10.3 0.0033 17.2 10.3 1.3 1 0 0 1 1 1 1 Laminin Domain I DUF4472 PF14739.6 EAX91528.1 - 0.0024 18.6 5.3 0.0084 16.8 5.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) TPR_MLP1_2 PF07926.12 EAX91528.1 - 0.0034 17.4 9.6 0.0034 17.4 9.6 1.8 2 0 0 2 2 1 1 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EAX91528.1 - 0.0038 17.1 7.7 0.0038 17.1 7.7 2.3 2 1 1 3 3 2 1 Protein of unknown function (DUF724) MAD PF05557.13 EAX91528.1 - 0.0039 15.6 11.1 0.0064 14.9 11.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein ADIP PF11559.8 EAX91528.1 - 0.0039 17.3 11.9 0.0039 17.3 11.9 2.6 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 EAX91528.1 - 0.0054 16.5 17.9 0.0054 16.5 17.9 1.8 2 0 0 2 2 1 1 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 EAX91528.1 - 0.0064 16.6 14.4 0.0064 16.6 14.4 1.9 2 1 1 3 3 2 1 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EAX91528.1 - 0.0068 17.1 11.5 0.0068 17.1 11.5 2.1 3 0 0 3 3 1 1 Occludin homology domain Golgin_A5 PF09787.9 EAX91528.1 - 0.0078 15.7 7.0 0.014 14.9 7.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 bZIP_1 PF00170.21 EAX91528.1 - 0.011 15.8 3.0 0.011 15.8 3.0 3.2 2 1 1 3 3 2 0 bZIP transcription factor Pox_A_type_inc PF04508.12 EAX91528.1 - 0.012 15.5 0.6 3 7.8 0.1 3.9 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat Filament PF00038.21 EAX91528.1 - 0.013 15.1 12.1 0.029 14.0 11.0 1.9 1 1 1 2 2 2 0 Intermediate filament protein Exonuc_VII_L PF02601.15 EAX91528.1 - 0.028 14.0 5.1 0.043 13.4 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fungal_TACC PF12709.7 EAX91528.1 - 0.033 14.6 16.1 0.58 10.6 2.9 3.7 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4200 PF13863.6 EAX91528.1 - 0.033 14.6 4.5 0.033 14.6 4.5 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3287 PF11690.8 EAX91528.1 - 0.036 13.8 0.4 0.15 11.8 0.1 2.0 1 1 0 2 2 1 0 Protein of unknown function (DUF3287) CREPT PF16566.5 EAX91528.1 - 0.045 13.9 8.2 0.66 10.1 6.1 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 EAX91528.1 - 0.047 13.0 4.4 0.075 12.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EAX91528.1 - 0.05 12.9 11.2 0.026 13.8 9.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 EAX91528.1 - 0.052 12.7 9.7 0.095 11.9 9.2 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region She9_MDM33 PF05546.11 EAX91528.1 - 0.063 13.1 5.1 0.14 12.0 5.1 1.6 1 0 0 1 1 1 0 She9 / Mdm33 family SKA2 PF16740.5 EAX91528.1 - 0.076 12.8 6.4 0.39 10.5 0.6 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 EAX91528.1 - 0.13 12.7 21.5 0.071 13.6 7.1 3.0 2 1 1 3 3 2 0 Cell division protein ZapB HemX PF04375.14 EAX91528.1 - 0.15 11.3 8.8 0.046 13.0 4.5 1.9 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase YlqD PF11068.8 EAX91528.1 - 0.17 12.2 9.1 0.39 11.1 9.1 1.6 1 0 0 1 1 1 0 YlqD protein USP8_interact PF08941.10 EAX91528.1 - 0.2 11.5 3.0 0.26 11.1 1.6 1.9 2 0 0 2 2 1 0 USP8 interacting ABC_tran_CTD PF16326.5 EAX91528.1 - 0.2 11.9 4.6 0.36 11.1 3.1 2.1 1 1 1 2 2 1 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 EAX91528.1 - 0.4 11.1 12.1 4.5 7.8 3.5 3.3 1 1 2 3 3 2 0 Flagella accessory protein C (FlaC) T3SSipB PF16535.5 EAX91528.1 - 0.46 10.9 7.3 0.95 9.9 7.3 1.5 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4140 PF13600.6 EAX91528.1 - 0.48 10.9 2.9 2.8 8.4 0.5 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 EAX91528.1 - 0.5 10.8 3.2 4.3 7.8 0.7 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 EAX91528.1 - 0.56 10.4 17.7 0.052 13.7 12.8 1.8 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 EAX91528.1 - 0.63 9.4 18.5 0.015 14.8 11.8 1.7 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal Nup54 PF13874.6 EAX91528.1 - 0.65 10.1 4.7 3.5 7.7 4.7 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Snapin_Pallidin PF14712.6 EAX91528.1 - 0.96 9.9 11.8 0.82 10.1 6.0 2.9 1 1 2 3 3 3 0 Snapin/Pallidin CALCOCO1 PF07888.11 EAX91528.1 - 1 8.2 10.8 0.39 9.5 6.5 2.1 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Noelin-1 PF12308.8 EAX91528.1 - 1.1 9.2 5.0 2 8.4 2.4 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein Uds1 PF15456.6 EAX91528.1 - 1.2 9.3 5.3 15 5.8 5.3 2.3 1 1 0 1 1 1 0 Up-regulated During Septation GIT_CC PF16559.5 EAX91528.1 - 1.2 9.0 13.7 0.06 13.2 3.6 3.1 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor LMBR1 PF04791.16 EAX91528.1 - 1.5 7.6 6.0 2.2 7.1 6.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CorA PF01544.18 EAX91528.1 - 1.6 8.0 7.6 3.6 6.8 7.7 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 EAX91528.1 - 1.9 8.7 18.3 0.34 11.1 11.4 2.9 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain CC2-LZ PF16516.5 EAX91528.1 - 2 8.9 11.2 4.3 7.8 2.6 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TolA_bind_tri PF16331.5 EAX91528.1 - 2 8.6 6.5 1.7 8.7 3.1 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 EAX91528.1 - 2.4 8.2 10.3 7.8 6.5 10.4 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EAX91528.1 - 2.7 7.5 8.2 5 6.7 3.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region BLOC1_2 PF10046.9 EAX91528.1 - 2.8 8.3 19.1 6.1 7.2 3.8 4.0 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 EAX91528.1 - 3.3 6.9 14.8 0.68 9.1 10.6 1.9 2 1 1 3 3 2 0 TMPIT-like protein Tropomyosin_1 PF12718.7 EAX91528.1 - 3.3 7.8 19.8 0.56 10.3 3.7 2.7 2 1 1 3 3 2 0 Tropomyosin like Alpha-2-MRAP_C PF06401.11 EAX91528.1 - 3.4 7.6 17.7 0.28 11.1 12.6 1.8 2 0 0 2 2 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Tnp_22_trimer PF17489.2 EAX91528.1 - 3.5 7.7 6.0 0.49 10.4 0.3 2.5 2 1 0 2 2 1 0 L1 transposable element trimerization domain DivIC PF04977.15 EAX91528.1 - 3.7 7.4 22.5 0.36 10.6 4.7 3.2 3 1 1 4 4 2 0 Septum formation initiator Tup_N PF08581.10 EAX91528.1 - 3.8 7.9 15.8 2 8.8 3.8 3.2 2 1 1 3 3 2 0 Tup N-terminal DUF2935 PF11155.8 EAX91528.1 - 4.8 7.5 10.4 7.7 6.9 4.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.12 EAX91528.1 - 4.9 7.7 7.8 1.9e+02 2.6 7.8 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EAX91528.1 - 5 7.8 15.4 0.74 10.5 8.3 3.0 2 1 1 3 3 2 0 Initiation control protein YabA FliJ PF02050.16 EAX91528.1 - 5.4 7.3 13.3 3 8.1 9.2 2.5 2 1 1 3 3 2 0 Flagellar FliJ protein DUF4201 PF13870.6 EAX91528.1 - 6 6.6 20.5 0.051 13.3 9.0 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4201) DUF2203 PF09969.9 EAX91528.1 - 6.9 7.4 7.0 3.3 8.5 3.6 2.2 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) BST2 PF16716.5 EAX91528.1 - 7.6 7.2 16.6 0.25 11.9 1.2 3.4 3 1 1 4 4 2 0 Bone marrow stromal antigen 2 Ax_dynein_light PF10211.9 EAX91528.1 - 9.1 6.2 18.2 4.5 7.2 3.5 2.6 2 1 1 3 3 2 0 Axonemal dynein light chain HIP1_clath_bdg PF16515.5 EAX91528.1 - 9.1 7.0 12.0 0.51 11.0 2.6 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 EAX91528.1 - 9.4 6.3 13.0 0.8 9.8 2.1 2.6 2 1 0 3 3 2 0 Designed helical repeat protein 10 domain WD40 PF00400.32 EAX91529.1 - 0.0024 18.7 1.2 25 6.0 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX91529.1 - 0.0041 17.4 0.8 1.5 9.2 0.0 4.9 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EAX91529.1 - 0.019 14.3 0.0 4.5 6.4 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 EAX91529.1 - 0.071 13.2 0.0 21 5.2 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Glyco_hydro_38C PF07748.13 EAX91530.1 - 7.2e-12 45.8 0.2 8.8e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain PSP PF04046.16 EAX91531.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91532.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Ank_4 PF13637.6 EAX91534.1 - 1.1e-16 60.9 1.0 5e-06 27.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91534.1 - 2.6e-13 50.4 4.8 1.1e-08 35.5 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91534.1 - 2.9e-13 49.7 0.5 6.8e-09 35.8 0.3 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91534.1 - 2.4e-12 46.7 3.7 0.011 16.1 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX91534.1 - 5.3e-10 38.7 1.1 0.79 10.5 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX91535.1 - 9.2e-49 163.2 11.7 1e-10 41.9 0.3 7.3 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91535.1 - 4.2e-46 155.4 15.6 2.5e-12 47.2 0.1 5.1 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91535.1 - 4.7e-37 124.8 6.2 0.00013 22.2 0.0 8.3 8 1 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAX91535.1 - 3.7e-35 116.0 9.6 6.1e-05 23.1 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX91535.1 - 8.2e-30 102.5 14.0 2.1e-09 37.5 0.3 5.6 4 2 1 5 5 5 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91535.1 - 4.2 7.4 9.7 30 4.6 0.0 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) DUF3447 PF11929.8 EAX91536.1 - 0.00018 21.4 3.7 0.0061 16.5 0.0 2.9 3 1 0 3 3 3 2 Domain of unknown function (DUF3447) EF-hand_1 PF00036.32 EAX91537.1 - 3.5e-29 98.2 12.3 2.5e-09 36.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX91537.1 - 1.9e-28 98.7 7.1 1.4e-16 60.7 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX91537.1 - 1.3e-24 83.9 5.2 3.9e-07 29.5 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX91537.1 - 1.9e-24 85.2 12.3 3.3e-14 52.5 0.7 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX91537.1 - 7.2e-17 60.0 10.7 2e-05 23.9 0.2 4.2 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EAX91537.1 - 2.6e-10 40.4 0.4 6e-06 26.5 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX91537.1 - 2.1e-07 31.2 3.8 0.00033 21.0 0.7 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EAX91537.1 - 2.6e-07 30.7 0.4 0.0025 18.0 0.0 2.6 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 EAX91537.1 - 9.8e-06 25.5 5.9 0.0014 18.5 1.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 EAX91537.1 - 0.00064 19.6 0.6 1 9.2 0.2 2.3 2 0 0 2 2 2 2 SurA N-terminal domain Caleosin PF05042.13 EAX91537.1 - 0.0019 18.1 1.3 0.58 10.1 0.0 3.0 1 1 1 3 3 3 1 Caleosin related protein DUF5580 PF17743.1 EAX91537.1 - 0.0052 15.4 0.1 0.014 13.9 0.0 1.6 1 1 1 2 2 2 1 Family of unknown function (DUF5580) DUF3008 PF11450.8 EAX91537.1 - 0.0092 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) EFhand_Ca_insen PF08726.10 EAX91537.1 - 0.03 14.4 0.4 4.2 7.5 0.1 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand TerB PF05099.13 EAX91537.1 - 0.047 13.6 0.8 5.9 6.9 0.1 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF2666 PF10869.8 EAX91537.1 - 0.096 12.9 2.6 0.21 11.8 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF1128 PF06569.11 EAX91537.1 - 0.5 10.4 4.4 0.53 10.3 0.3 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1128) AAA PF00004.29 EAX91538.1 - 1.8e-15 57.5 0.0 4.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX91538.1 - 4.4e-09 36.9 0.0 1.9e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX91538.1 - 7.8e-08 32.7 0.0 2.1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 EAX91538.1 - 1e-06 28.6 0.0 1.5e-05 24.8 0.0 2.5 2 1 0 2 2 2 1 BAH domain NACHT PF05729.12 EAX91538.1 - 0.00025 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 EAX91538.1 - 0.00061 19.9 0.1 0.002 18.2 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 EAX91538.1 - 0.011 15.0 0.1 0.036 13.3 0.0 1.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EAX91538.1 - 0.033 14.0 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAX91538.1 - 0.05 13.8 0.2 0.15 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAX91538.1 - 0.073 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EAX91538.1 - 0.13 12.0 0.2 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EAX91538.1 - 0.96 9.8 3.1 0.87 9.9 0.4 2.2 3 0 0 3 3 3 0 AAA domain DHC_N2 PF08393.13 EAX91539.1 - 5.6e-77 259.5 7.5 5.6e-77 259.5 7.5 3.7 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EAX91539.1 - 4.7e-31 108.0 1.2 4.7e-31 108.0 1.2 3.1 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EAX91539.1 - 6.2e-09 35.6 0.2 7.3e-08 32.1 0.4 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 EAX91539.1 - 1.9e-08 34.4 0.0 5.1e-05 23.3 0.0 4.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 EAX91539.1 - 6.3e-06 25.7 1.4 6.3e-06 25.7 1.4 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EAX91539.1 - 2.8e-05 24.0 0.0 0.00011 22.1 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EAX91539.1 - 5.4e-05 23.5 3.5 0.32 11.3 0.0 5.9 6 0 0 6 6 6 1 AAA domain AAA_16 PF13191.6 EAX91539.1 - 0.0032 17.9 0.0 0.36 11.2 0.0 3.9 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 EAX91539.1 - 0.0081 15.3 0.0 3.2 6.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 EAX91539.1 - 0.022 15.2 0.0 17 5.8 0.0 4.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAX91539.1 - 0.037 14.4 0.2 90 3.5 0.0 5.3 5 0 0 5 5 5 0 RNA helicase Sigma54_activ_2 PF14532.6 EAX91539.1 - 0.043 13.9 0.0 7.7 6.6 0.0 3.4 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 EAX91539.1 - 0.053 13.2 0.0 0.47 10.1 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain NACHT PF05729.12 EAX91539.1 - 0.055 13.4 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EAX91539.1 - 0.055 12.8 0.2 7.1 5.9 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Cluap1 PF10234.9 EAX91539.1 - 0.43 9.9 26.7 0.19 11.1 10.5 3.7 3 0 0 3 3 3 0 Clusterin-associated protein-1 COG2 PF06148.11 EAX91539.1 - 2 8.5 18.4 1.2 9.2 3.8 4.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EAX91539.1 - 2.9 6.7 37.2 0.25 10.2 12.8 4.1 4 0 0 4 4 4 0 Spc7 kinetochore protein NAPRTase_N PF17767.1 EAX91539.1 - 2.9 8.3 6.9 10 6.5 3.1 3.5 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Pkinase PF00069.25 EAX91540.1 - 6.6e-26 91.2 0.0 7.9e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91540.1 - 7.4e-13 48.4 0.0 9.1e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX91540.1 - 9.9e-07 28.9 0.0 3.2e-05 24.0 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX91540.1 - 0.00045 19.1 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX91540.1 - 0.00064 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX91540.1 - 0.0036 16.7 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like LRR_5 PF13306.6 EAX91542.1 - 2.5e-53 179.4 19.3 1.8e-27 95.8 0.6 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91542.1 - 6.6e-08 32.2 0.2 0.27 11.0 0.0 5.0 4 2 1 5 5 5 3 Leucine rich repeat LRR_5 PF13306.6 EAX91543.1 - 1.3e-19 70.4 4.7 1.3e-19 70.4 4.7 1.5 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX91545.1 - 8.6e-85 281.1 70.4 2.3e-28 98.7 4.7 5.2 3 1 1 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91545.1 - 6.5e-10 38.6 7.9 0.12 12.2 0.1 7.4 4 2 5 9 9 9 4 Leucine rich repeat Cytomega_UL84 PF06284.11 EAX91546.1 - 0.98 7.8 7.3 1 7.8 7.3 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Peptidase_S49_N PF08496.10 EAX91546.1 - 3.8 7.6 7.6 3.8 7.6 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRR_5 PF13306.6 EAX91550.1 - 6e-87 288.1 57.9 1.5e-27 96.1 2.2 5.9 3 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91550.1 - 6.7e-24 83.4 6.2 5.4e-05 22.9 0.2 9.1 6 3 4 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 EAX91550.1 - 0.0051 17.2 17.4 0.24 11.9 0.2 6.8 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) DUF2163 PF09931.9 EAX91551.1 - 0.028 14.7 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) UCH PF00443.29 EAX91552.1 - 6.4e-49 166.8 1.9 1.3e-48 165.7 1.9 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX91552.1 - 5e-28 98.6 1.5 2.7e-26 93.0 1.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAX91552.1 - 2.2e-08 33.7 3.3 3e-08 33.3 0.3 2.7 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 BBP1_N PF15271.6 EAX91552.1 - 0.0065 17.3 1.7 0.02 15.7 1.7 1.8 1 0 0 1 1 1 1 Spindle pole body component BBP1, Mps2-binding protein PI3K_rbd PF00794.18 EAX91552.1 - 0.14 12.3 1.8 0.62 10.2 0.2 2.6 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain PLU-1 PF08429.11 EAX91553.1 - 0.18 10.9 0.5 0.31 10.2 0.5 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF4352 PF11611.8 EAX91554.1 - 0.19 12.0 5.3 6.2 7.1 4.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4352) Ank_2 PF12796.7 EAX91555.1 - 0.00023 21.7 0.3 1.2 9.7 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX91555.1 - 0.00046 20.1 3.0 0.00046 20.1 3.0 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) HEAT_2 PF13646.6 EAX91556.1 - 4.9e-15 55.7 0.8 0.00014 22.2 0.0 4.5 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 EAX91556.1 - 7.8e-09 35.1 15.3 0.79 10.1 0.1 8.5 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 EAX91556.1 - 0.0016 18.5 1.5 0.32 11.0 0.2 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAX91556.1 - 0.023 15.3 0.7 13 6.4 0.0 3.7 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAX91556.1 - 0.054 14.0 3.4 5.2 7.7 0.2 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF4223 PF13978.6 EAX91556.1 - 0.069 13.1 0.2 0.88 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) RTP1_C1 PF10363.9 EAX91556.1 - 0.086 13.0 1.0 16 5.7 0.1 3.5 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Daxx PF03344.15 EAX91557.1 - 5.4e-05 23.2 0.1 0.93 9.6 0.0 2.9 1 1 2 3 3 3 3 Daxx N-terminal Rassf1C-interacting domain zinc_ribbon_2 PF13240.6 EAX91557.1 - 0.00058 19.5 3.1 17 5.3 0.0 4.3 4 0 0 4 4 4 3 zinc-ribbon domain MBD PF01429.19 EAX91557.1 - 0.0058 16.3 0.0 6.5 6.5 0.0 3.0 1 1 1 2 2 2 2 Methyl-CpG binding domain CholecysA-Rec_N PF09193.10 EAX91557.1 - 0.006 16.6 0.0 4.2 7.5 0.0 2.6 1 1 1 2 2 2 2 Cholecystokinin A receptor, N-terminal DZR PF12773.7 EAX91557.1 - 0.0065 16.5 1.0 0.93 9.6 1.0 3.1 1 1 0 1 1 1 1 Double zinc ribbon NDUF_B8 PF05821.11 EAX91557.1 - 0.0078 16.1 0.0 0.63 9.9 0.0 2.1 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF4733 PF15878.5 EAX91557.1 - 0.011 16.2 0.1 27 5.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4733) ATPase-cat_bd PF12156.8 EAX91557.1 - 0.026 15.2 1.1 5.4 7.8 0.1 3.0 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase PSD2 PF07624.11 EAX91557.1 - 0.042 13.6 0.0 8.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) zf-ribbon_3 PF13248.6 EAX91557.1 - 0.077 12.4 2.3 39 3.8 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF3447 PF11929.8 EAX91558.1 - 0.00012 21.9 3.9 0.00012 21.9 3.9 2.6 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX91558.1 - 0.00013 22.5 0.2 0.035 14.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91558.1 - 0.072 13.7 0.0 38 5.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91558.1 - 0.073 13.7 0.0 11 7.0 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat DUF4108 PF13390.6 EAX91559.1 - 1e-58 197.3 5.2 1.1e-58 197.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX91559.1 - 0.095 13.0 0.1 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_A32 PF04665.12 EAX91561.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX91561.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX91561.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX91561.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91561.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX91561.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX91561.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX91561.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX91561.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX91561.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX91561.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX91561.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX91562.1 - 4.9e-80 268.5 11.6 6.5e-80 268.1 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX91562.1 - 0.071 12.6 0.7 0.27 10.7 0.1 2.2 2 1 0 2 2 2 0 SLOG cluster2 DUF2408 PF10303.9 EAX91562.1 - 0.098 13.2 0.5 0.16 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PRD PF00874.20 EAX91562.1 - 0.12 12.7 1.3 0.31 11.4 0.1 2.3 3 0 0 3 3 3 0 PRD domain Bromodomain PF00439.25 EAX91563.1 - 2.5e-24 85.1 0.3 6.8e-24 83.7 0.2 1.9 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 EAX91563.1 - 4.4e-05 23.6 0.0 9.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation RICH PF05062.12 EAX91563.1 - 0.0015 18.8 1.1 0.0033 17.7 1.1 1.6 1 0 0 1 1 1 1 RICH domain Bcl-2_3 PF15286.6 EAX91563.1 - 0.055 14.1 0.1 0.24 12.0 0.0 2.0 2 1 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Serine_rich PF08824.10 EAX91563.1 - 0.075 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain VPS9 PF02204.18 EAX91564.1 - 8.4e-08 32.4 2.1 1.4e-06 28.5 0.0 3.3 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF3385 PF11865.8 EAX91564.1 - 0.2 11.6 4.8 5.5 6.9 0.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) PMT PF02366.18 EAX91565.1 - 2.4e-26 92.8 15.3 4.2e-26 92.0 15.3 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Peptidase_M60 PF13402.6 EAX91567.1 - 9.2e-69 232.0 0.5 1.4e-68 231.4 0.5 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 EAX91567.1 - 4.3e-23 81.3 0.1 1.3e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases Imm64 PF15600.6 EAX91567.1 - 0.091 12.4 0.1 0.41 10.3 0.1 2.1 1 1 0 1 1 1 0 Immunity protein 64 Flp1_like PF16982.5 EAX91568.1 - 0.097 12.1 4.4 0.24 10.8 4.4 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain ABC2_membrane_3 PF12698.7 EAX91569.1 - 1.7e-13 50.5 22.8 2.2e-13 50.0 22.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DBP10CT PF08147.12 EAX91569.1 - 0.023 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain ABC_tran PF00005.27 EAX91570.1 - 1.8e-13 51.2 0.0 2.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX91570.1 - 9.1e-07 29.0 0.2 1.3e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX91570.1 - 2.4e-05 23.9 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EAX91570.1 - 0.038 14.2 0.0 0.32 11.2 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Serinc PF03348.15 EAX91571.1 - 5.1e-51 173.9 38.2 7.6e-51 173.4 38.2 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2615 PF11027.8 EAX91571.1 - 0.029 14.5 1.7 0.79 9.9 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) PSP PF04046.16 EAX91573.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PTR PF12789.7 EAX91575.1 - 6.1e-05 23.0 0.3 6.1e-05 23.0 0.3 4.3 5 1 0 5 5 5 1 Phage tail repeat like DUF445 PF04286.12 EAX91575.1 - 0.0054 16.6 5.7 0.0082 16.0 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAX91575.1 - 0.035 14.5 0.6 0.16 12.4 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) EDR1 PF14381.6 EAX91575.1 - 0.1 12.3 0.1 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 MeaB PF03308.16 EAX91575.1 - 0.15 11.0 0.7 0.24 10.3 0.7 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4795 PF16043.5 EAX91575.1 - 1 8.9 15.2 0.23 11.1 7.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Pox_D5 PF03288.16 EAX91577.1 - 2.2e-05 24.9 2.2 0.00012 22.5 2.2 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX91577.1 - 0.014 16.0 0.1 0.027 15.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX91577.1 - 0.039 13.9 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain NMT PF01233.19 EAX91578.1 - 0.069 13.0 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain GGDEF PF00990.21 EAX91578.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF1493 PF07377.12 EAX91579.1 - 0.1 13.1 0.7 0.24 11.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HIRA_B PF09453.10 EAX91579.1 - 0.14 12.1 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 HIRA B motif TMP PF05017.14 EAX91580.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat HALZ PF02183.18 EAX91581.1 - 6.1e-06 26.4 6.8 6.1e-06 26.4 6.8 21.2 15 9 4 20 20 20 4 Homeobox associated leucine zipper Spc7 PF08317.11 EAX91581.1 - 9.4e-06 24.7 88.0 1.6e-05 24.0 38.1 10.4 1 1 10 12 12 12 5 Spc7 kinetochore protein PRKG1_interact PF15898.5 EAX91581.1 - 0.00091 20.1 20.3 0.00091 20.1 20.3 14.8 4 2 11 15 15 15 2 cGMP-dependent protein kinase interacting domain GAS PF13851.6 EAX91581.1 - 0.002 17.5 31.5 0.002 17.5 31.5 12.9 3 2 9 13 13 13 4 Growth-arrest specific micro-tubule binding YabA PF06156.13 EAX91581.1 - 0.0033 18.0 10.8 0.0033 18.0 10.8 17.3 4 2 14 18 18 18 4 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EAX91581.1 - 0.004 17.2 19.3 0.004 17.2 19.3 13.6 5 4 7 12 12 12 4 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EAX91581.1 - 0.0076 16.3 6.5 0.0076 16.3 6.5 14.3 4 2 9 15 15 15 3 Protein of unknown function (DUF1664) ATG16 PF08614.11 EAX91581.1 - 1.3 9.2 244.6 0.068 13.4 34.1 11.0 2 1 8 10 10 10 0 Autophagy protein 16 (ATG16) DUF3320 PF11784.8 EAX91582.1 - 0.21 11.6 0.1 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) Myb_DNA-binding PF00249.31 EAX91583.1 - 3.1e-06 27.3 0.2 8.8e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91583.1 - 0.0064 16.7 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EAX91583.1 - 0.084 12.7 4.3 0.18 11.6 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_2 PF03107.16 EAX91583.1 - 0.38 11.1 5.0 0.91 9.9 5.0 1.6 1 0 0 1 1 1 0 C1 domain Gly-zipper_Omp PF13488.6 EAX91585.1 - 0.02 14.9 10.4 0.035 14.1 10.4 1.4 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX91585.1 - 0.51 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Smr PF01713.21 EAX91586.1 - 0.00084 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Smr domain RLL PF10036.9 EAX91586.1 - 0.014 15.3 1.8 0.016 15.1 1.8 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein GIDA_assoc PF13932.6 EAX91586.1 - 0.017 15.3 3.2 0.022 15.0 3.2 1.1 1 0 0 1 1 1 0 GidA associated domain PV-1 PF06637.11 EAX91586.1 - 0.033 13.0 1.7 0.041 12.7 1.7 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF5611 PF18446.1 EAX91586.1 - 0.069 14.0 3.9 2.1 9.3 3.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5611) ThiD2 PF17792.1 EAX91586.1 - 0.075 13.5 0.7 0.13 12.8 0.4 1.6 1 1 0 1 1 1 0 ThiD2 family HSCB_C PF07743.13 EAX91586.1 - 0.12 12.8 2.6 0.26 11.8 2.0 1.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Peptidase_S49_N PF08496.10 EAX91586.1 - 2.4 8.2 6.1 1.2 9.2 4.2 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal TPR_MLP1_2 PF07926.12 EAX91590.1 - 0.0075 16.3 0.4 0.0094 16.0 0.4 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX91590.1 - 0.061 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX91590.1 - 0.93 9.5 9.9 0.3 11.0 4.4 2.4 3 0 0 3 3 3 0 Spo12 family Exo_endo_phos PF03372.23 EAX91591.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dus PF01207.17 EAX91592.1 - 1.4e-50 172.2 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EAX91592.1 - 3.1e-07 30.1 0.5 6.7e-07 29.0 0.5 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EAX91592.1 - 0.00056 19.2 0.1 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 EAX91592.1 - 0.0012 18.2 0.2 0.0021 17.4 0.2 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 EAX91592.1 - 0.002 17.5 0.5 0.0038 16.6 0.2 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase PEP_mutase PF13714.6 EAX91592.1 - 0.0073 15.8 0.3 0.18 11.3 0.0 2.1 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase DeoC PF01791.9 EAX91592.1 - 0.015 14.9 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase NMO PF03060.15 EAX91592.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase G3P_antiterm PF04309.12 EAX91592.1 - 0.043 13.2 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator SOR_SNZ PF01680.17 EAX91592.1 - 0.049 13.4 2.4 0.24 11.1 0.1 2.4 2 1 1 3 3 3 0 SOR/SNZ family Trp_syntA PF00290.20 EAX91592.1 - 0.075 11.9 1.6 0.15 10.9 0.4 2.0 2 1 1 3 3 3 0 Tryptophan synthase alpha chain DSPc PF00782.20 EAX91593.1 - 3.1e-26 91.7 0.0 5.9e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAX91593.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EAX91593.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain F5_F8_type_C PF00754.25 EAX91595.1 - 1.7e-08 34.6 0.1 1.7e-08 34.6 0.1 5.7 6 1 0 7 7 7 1 F5/8 type C domain Big_5 PF13205.6 EAX91595.1 - 0.00016 22.4 9.2 0.0039 17.9 0.1 4.3 4 0 0 4 4 4 2 Bacterial Ig-like domain TMEM154 PF15102.6 EAX91595.1 - 0.03 14.2 0.3 0.068 13.1 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family PSP PF04046.16 EAX91596.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91597.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX91598.1 - 0.067 13.7 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1116 PF06545.11 EAX91599.1 - 0.22 10.9 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) GPS2_interact PF15784.5 EAX91600.1 - 0.066 13.6 0.9 0.087 13.3 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KilA-N PF04383.13 EAX91601.1 - 1.7e-32 111.6 0.6 3.6e-32 110.5 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain PCI PF01399.27 EAX91603.1 - 0.43 11.1 4.4 1 9.9 0.0 3.2 3 1 0 3 3 3 0 PCI domain PHD PF00628.29 EAX91604.1 - 4.7e-07 29.6 7.5 7.6e-07 28.9 7.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EAX91604.1 - 0.0003 21.3 3.4 0.00036 21.1 2.3 1.6 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 EAX91604.1 - 0.018 15.3 4.7 0.061 13.6 4.6 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain Hirudin PF00713.17 EAX91604.1 - 0.05 13.9 0.9 0.095 13.0 0.9 1.5 1 0 0 1 1 1 0 Hirudin zf-HC5HC2H_2 PF13832.6 EAX91604.1 - 0.12 12.5 4.5 0.15 12.3 1.8 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EAX91604.1 - 0.17 12.2 3.7 0.37 11.1 3.7 1.5 1 0 0 1 1 1 0 RING-like domain ATG16 PF08614.11 EAX91605.1 - 0.00043 20.6 31.8 0.00043 20.6 31.8 7.4 3 2 3 6 6 6 3 Autophagy protein 16 (ATG16) VASP_tetra PF08776.11 EAX91605.1 - 3.6 7.2 22.3 0.72 9.5 0.4 6.2 5 0 0 5 5 5 0 VASP tetramerisation domain DUF3552 PF12072.8 EAX91607.1 - 0.00016 21.2 22.4 0.0002 20.8 22.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Glutaredoxin2_C PF04399.13 EAX91607.1 - 0.028 14.2 1.2 0.034 14.0 1.2 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Exonuc_VII_L PF02601.15 EAX91607.1 - 0.089 12.4 7.2 0.11 12.1 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RIC3 PF15361.6 EAX91607.1 - 1.1 9.7 6.5 1.5 9.2 6.5 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4407 PF14362.6 EAX91607.1 - 1.5 8.1 6.7 1.6 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EAX91607.1 - 2.2 6.8 10.6 2.3 6.7 10.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EAX91607.1 - 2.3 6.0 6.6 2.7 5.8 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GPHR_N PF12537.8 EAX91607.1 - 3.9 7.6 4.1 13 5.9 4.1 2.1 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PspB PF06667.12 EAX91607.1 - 4.4 7.4 7.0 7.1 6.8 6.9 1.6 1 1 0 1 1 1 0 Phage shock protein B TMPIT PF07851.13 EAX91607.1 - 5.3 6.2 7.6 6.3 6.0 7.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein T3SS_needle_E PF08988.10 EAX91607.1 - 6.1 7.1 8.5 20 5.4 1.5 2.4 1 1 2 3 3 3 0 Type III secretion system, cytoplasmic E component of needle VWA_3 PF13768.6 EAX91608.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX91608.1 - 4.2e-16 59.7 0.0 9.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EAX91608.1 - 1.8e-13 50.6 0.1 6.8e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EAX91608.1 - 6.3e-12 46.1 0.0 2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAX91608.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein RPN6_N PF18055.1 EAX91609.1 - 0.029 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Xpo1 PF08389.12 EAX91609.1 - 0.049 13.7 0.3 0.049 13.7 0.3 3.4 5 0 0 5 5 5 0 Exportin 1-like protein SWC7 PF17330.2 EAX91609.1 - 0.2 11.7 2.4 1.1 9.3 0.2 3.1 3 0 0 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 WD40 PF00400.32 EAX91610.1 - 3.7e-06 27.6 0.3 0.0073 17.1 0.1 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat CDC24 PF06395.11 EAX91610.1 - 0.13 12.5 0.2 0.42 10.9 0.2 1.8 1 0 0 1 1 1 0 CDC24 Calponin Ank_2 PF12796.7 EAX91611.1 - 3.3e-60 200.6 22.1 3.4e-17 62.8 0.9 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91611.1 - 1.1e-56 188.5 12.4 4e-14 52.8 0.1 8.6 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX91611.1 - 5.1e-52 172.2 11.3 1.1e-08 35.1 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX91611.1 - 1.2e-50 168.9 10.9 2e-15 56.7 0.1 6.1 3 3 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91611.1 - 6.5e-41 133.6 11.9 2.5e-06 27.4 0.1 8.5 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 EAX91611.1 - 1.4e-38 130.7 6.1 1.4e-38 130.7 6.1 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX91611.1 - 0.0001 22.5 0.0 0.075 13.3 0.0 3.5 1 1 1 3 3 3 2 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX91611.1 - 0.00019 21.6 0.4 31 4.9 0.0 4.8 1 1 4 5 5 5 0 Pleckstrin homology domain Staphylokinase PF02821.16 EAX91611.1 - 0.0037 17.7 0.6 14 6.1 0.0 4.5 1 1 4 5 5 5 0 Staphylokinase/Streptokinase family GATase_7 PF13537.6 EAX91611.1 - 0.004 17.1 0.0 22 5.0 0.0 4.7 1 1 3 4 4 4 0 Glutamine amidotransferase domain Mic1 PF07035.12 EAX91611.1 - 0.005 16.6 0.2 13 5.5 0.0 3.7 3 1 1 4 4 4 0 Colon cancer-associated protein Mic1-like ThiS-like PF14453.6 EAX91611.1 - 0.0064 16.5 8.0 21 5.2 0.1 6.1 5 1 1 6 6 6 0 ThiS-like ubiquitin Ribosomal_S6 PF01250.17 EAX91611.1 - 0.0091 16.2 1.0 11 6.3 0.0 4.4 2 1 3 5 5 5 1 Ribosomal protein S6 DUF4261 PF14080.6 EAX91611.1 - 0.067 13.3 0.6 11 6.3 0.0 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4261) RL PF17797.1 EAX91611.1 - 1.4 9.0 7.0 2.8 7.9 0.3 3.9 3 0 0 3 3 3 0 RL domain Myb_DNA-binding PF00249.31 EAX91613.1 - 4.2e-30 103.7 2.3 4.8e-15 55.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91613.1 - 5.7e-22 77.7 2.3 1.7e-11 44.2 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91613.1 - 7.8e-07 29.1 1.4 0.0052 16.8 0.2 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91613.1 - 0.0009 19.1 0.2 0.0094 15.8 0.1 2.3 1 1 1 2 2 2 1 Myb DNA-binding like HTH_23 PF13384.6 EAX91613.1 - 0.018 14.8 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Skp1 PF01466.19 EAX91613.1 - 0.035 14.2 0.1 56 4.0 0.0 3.8 4 0 0 4 4 4 0 Skp1 family, dimerisation domain NifQ PF04891.12 EAX91613.1 - 0.16 12.3 0.3 13 6.1 0.0 2.2 2 0 0 2 2 2 0 NifQ Myb_DNA-bind_2 PF08914.11 EAX91613.1 - 0.19 11.9 2.9 0.91 9.7 0.3 3.0 1 1 1 2 2 2 0 Rap1 Myb domain AAA_24 PF13479.6 EAX91614.1 - 0.025 14.3 4.4 2.1 8.0 0.7 2.6 1 1 1 2 2 2 0 AAA domain Antimicrobial_2 PF08023.12 EAX91614.1 - 0.08 13.5 6.2 13 6.4 0.3 4.5 4 0 0 4 4 4 0 Frog antimicrobial peptide Sec66 PF09802.9 EAX91614.1 - 0.4 10.2 6.3 2.5 7.7 0.3 3.4 3 0 0 3 3 3 0 Preprotein translocase subunit Sec66 Ribosomal_L18p PF00861.22 EAX91614.1 - 1.2 9.5 3.5 1.5 9.2 0.5 2.6 2 1 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast I_LWEQ PF01608.17 EAX91614.1 - 4.2 7.6 6.2 1.5 9.1 0.2 3.0 3 1 1 4 4 4 0 I/LWEQ domain DUF2642 PF10842.8 EAX91614.1 - 4.6 7.2 7.0 6.8 6.6 0.2 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2642) Myb_DNA-binding PF00249.31 EAX91615.1 - 1.7e-23 82.5 2.0 3.3e-13 49.6 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91615.1 - 3.1e-23 81.8 5.3 6.3e-12 45.6 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX91615.1 - 4.2e-06 26.6 1.3 0.00053 19.8 0.5 2.8 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX91615.1 - 0.00027 20.9 1.8 0.12 12.4 0.1 2.7 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EAX91615.1 - 0.011 15.9 0.7 0.024 14.8 0.7 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 HTH_32 PF13565.6 EAX91615.1 - 0.034 14.8 0.2 9 7.0 0.0 2.3 1 1 1 2 2 2 0 Homeodomain-like domain Y1_Tnp PF01797.16 EAX91615.1 - 0.1 12.7 2.1 6.2 7.0 0.2 2.3 2 1 0 2 2 2 0 Transposase IS200 like Myb_DNA-bind_2 PF08914.11 EAX91615.1 - 0.11 12.7 5.0 3.3 8.0 0.2 3.4 1 1 1 2 2 2 0 Rap1 Myb domain DUF5641 PF18701.1 EAX91615.1 - 0.13 12.5 1.7 0.51 10.5 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5641) DUF4065 PF13274.6 EAX91615.1 - 0.34 11.8 4.0 0.45 11.4 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) Myb_DNA-bind_6 PF13921.6 EAX91616.1 - 1.3e-21 76.6 4.9 1.6e-14 53.9 1.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX91616.1 - 3.1e-19 68.9 0.9 4.1e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1877 PF08974.10 EAX91616.1 - 0.02 15.0 0.0 0.1 12.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1877) Myb_DNA-bind_7 PF15963.5 EAX91616.1 - 0.023 14.6 0.8 0.063 13.2 0.1 2.1 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX91616.1 - 0.03 14.5 0.2 0.47 10.7 0.0 2.5 2 1 0 2 2 2 0 Rap1 Myb domain Atg29_N PF18388.1 EAX91616.1 - 0.047 13.5 0.6 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Atg29 N-terminal domain Myb_DNA-bind_4 PF13837.6 EAX91616.1 - 0.14 12.6 4.2 0.72 10.3 2.9 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Sgf11 PF08209.11 EAX91617.1 - 0.32 10.6 1.5 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Med9 PF07544.13 EAX91617.1 - 0.4 10.8 29.2 0.4 10.8 6.4 4.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Hsk3 PF08227.11 EAX91617.1 - 3.1 8.2 13.6 3.3 8.2 1.4 3.4 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Prismane PF03063.20 EAX91617.1 - 3.2 6.3 12.1 0.097 11.3 3.6 2.4 1 1 2 3 3 3 0 Prismane/CO dehydrogenase family NPV_P10 PF05531.12 EAX91617.1 - 3.6 8.1 22.9 1.4 9.4 3.0 5.0 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 EAX91617.1 - 4.6 7.7 13.2 0.29 11.6 0.4 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper SlyX PF04102.12 EAX91617.1 - 5 7.8 18.1 3.9 8.2 1.3 4.6 5 0 0 5 5 5 0 SlyX SYCP2_ARLD PF18581.1 EAX91618.1 - 0.082 12.9 0.7 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain Thioredoxin PF00085.20 EAX91620.1 - 1.1e-14 54.2 0.1 1.3e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX91620.1 - 1.7e-05 25.1 0.0 3.6e-05 24.0 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EAX91620.1 - 0.0018 18.2 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 EAX91620.1 - 0.0063 15.5 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EAX91620.1 - 0.016 15.7 0.1 0.042 14.3 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EAX91620.1 - 0.037 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 EAX91620.1 - 0.037 14.1 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Toxin-deaminase PF14424.6 EAX91620.1 - 0.057 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Glutaredoxin PF00462.24 EAX91620.1 - 0.097 12.9 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 EAX91620.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF3447 PF11929.8 EAX91621.1 - 1.5e-21 76.1 11.9 1.7e-19 69.6 5.5 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX91621.1 - 3.4e-11 43.1 0.3 0.0015 18.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91621.1 - 1e-07 32.4 4.4 0.00053 20.5 0.4 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91621.1 - 0.00092 19.7 0.0 0.13 12.9 0.0 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91621.1 - 0.012 16.1 2.5 2.8 8.8 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 EAX91621.1 - 0.028 14.9 0.0 0.26 11.8 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Myb_DNA-bind_6 PF13921.6 EAX91622.1 - 4.2e-23 81.4 1.3 1.2e-11 44.7 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX91622.1 - 1.8e-21 76.1 0.3 2.2e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91622.1 - 7.6e-05 22.7 0.3 0.18 11.8 0.1 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91622.1 - 0.0033 17.3 3.6 0.01 15.7 1.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX91622.1 - 0.0083 16.3 0.2 0.016 15.4 0.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 EAX91623.1 - 1.1e-39 136.5 0.0 1.6e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91623.1 - 4.9e-16 58.8 0.0 1e-15 57.7 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX91623.1 - 0.12 12.2 0.0 0.57 10.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family IF4E PF01652.18 EAX91624.1 - 4.1e-08 33.2 0.0 4.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IDEAL PF08858.10 EAX91624.1 - 0.074 12.8 0.5 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 IDEAL domain Pkinase PF00069.25 EAX91626.1 - 4.8e-27 95.0 0.0 6.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91626.1 - 2.1e-10 40.3 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX91626.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX91626.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBD PF10416.9 EAX91627.1 - 2.3e-44 150.5 0.9 3.7e-44 149.8 0.9 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD CpxA_peri PF16527.5 EAX91628.1 - 0.016 15.6 0.4 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain RhoGEF PF00621.20 EAX91628.1 - 0.024 14.9 7.2 2.2 8.5 3.6 2.4 1 1 1 2 2 2 0 RhoGEF domain Abi_2 PF07751.11 EAX91628.1 - 0.034 14.4 3.1 0.053 13.8 0.2 2.2 1 1 1 2 2 2 0 Abi-like protein Apolipoprotein PF01442.18 EAX91629.1 - 1.4e-25 90.3 207.2 0.00013 21.9 13.8 13.3 2 2 12 14 14 14 12 Apolipoprotein A1/A4/E domain COG5 PF10392.9 EAX91629.1 - 8.4e-05 22.8 9.3 8.4e-05 22.8 9.3 19.9 5 2 16 23 23 23 1 Golgi transport complex subunit 5 Col_cuticle_N PF01484.17 EAX91629.1 - 0.00097 19.1 2.0 0.13 12.3 0.0 5.4 4 0 0 4 4 4 1 Nematode cuticle collagen N-terminal domain CLZ PF16526.5 EAX91629.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 25.6 13 7 11 27 27 27 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 EAX91629.1 - 0.0012 19.0 6.0 0.0012 19.0 6.0 19.7 3 3 15 21 21 21 7 Fibrinogen alpha/beta chain family EspB PF05802.11 EAX91629.1 - 0.0032 17.5 5.6 0.0032 17.5 5.6 15.6 5 4 8 14 14 14 2 Enterobacterial EspB protein DUF3584 PF12128.8 EAX91629.1 - 0.01 13.4 299.7 0.029 11.9 13.5 9.3 1 1 7 9 9 9 0 Protein of unknown function (DUF3584) Fungal_TACC PF12709.7 EAX91629.1 - 0.011 16.1 2.4 0.011 16.1 2.4 22.2 11 9 15 28 28 28 0 Fungal Transforming acidic coiled-coil (TACC) proteins PMC2NT PF08066.12 EAX91629.1 - 0.016 15.8 0.5 0.016 15.8 0.5 19.0 7 5 12 19 19 19 0 PMC2NT (NUC016) domain FtsZ_C PF12327.8 EAX91629.1 - 0.63 10.4 5.3 0.84 10.0 0.1 4.1 3 1 0 3 3 3 0 FtsZ family, C-terminal domain DUF3781 PF12636.7 EAX91630.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX91631.1 - 0.12 11.4 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ras PF00071.22 EAX91632.1 - 1.7e-54 183.8 0.5 2e-54 183.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91632.1 - 1.9e-19 70.0 0.0 2.9e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91632.1 - 7.2e-12 45.1 0.0 9.2e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX91632.1 - 6e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX91632.1 - 5.5e-06 26.4 0.1 0.011 15.6 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX91632.1 - 0.0028 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAX91632.1 - 0.12 11.9 0.1 0.51 9.9 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 EAX91632.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SF3A3 PF16837.5 EAX91633.1 - 0.0093 16.5 5.3 0.25 11.9 0.9 2.4 2 0 0 2 2 2 2 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Syntaxin-6_N PF09177.11 EAX91634.1 - 0.027 15.0 0.2 0.034 14.7 0.2 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF2408 PF10303.9 EAX91634.1 - 0.041 14.4 0.4 0.053 14.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Heme_oxygenase PF01126.20 EAX91634.1 - 0.062 13.1 0.0 0.079 12.7 0.0 1.0 1 0 0 1 1 1 0 Heme oxygenase Sybindin PF04099.12 EAX91635.1 - 1.9e-21 76.5 0.1 2.5e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAX91635.1 - 9.5e-06 25.8 0.2 1.1e-05 25.6 0.2 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region TraA PF05513.11 EAX91636.1 - 0.014 15.7 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 TraA QLQ PF08880.11 EAX91636.1 - 0.033 13.9 1.1 0.049 13.4 0.3 1.7 2 0 0 2 2 2 0 QLQ DUF1413 PF07205.11 EAX91636.1 - 0.088 12.8 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) DUF848 PF05852.11 EAX91637.1 - 0.00045 20.4 4.0 0.00046 20.3 4.0 1.0 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) HSBP1 PF06825.12 EAX91637.1 - 0.014 15.2 4.1 0.037 13.9 4.1 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 SASP PF00269.20 EAX91637.1 - 0.085 12.9 0.2 0.085 12.9 0.2 1.6 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type FYRC PF05965.14 EAX91638.1 - 2e-17 63.1 0.0 5e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 EAX91638.1 - 1.2e-15 57.0 0.0 2.7e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Chromo PF00385.24 EAX91638.1 - 3e-08 33.4 5.6 0.00064 19.6 0.2 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain TetR_C_19 PF17924.1 EAX91641.1 - 0.029 15.0 0.4 0.032 14.8 0.4 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tristanin_u2 PF16638.5 EAX91642.1 - 2.7 8.9 5.0 5 8.0 4.5 1.7 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers DUF4107 PF13389.6 EAX91644.1 - 4.1e-71 238.4 3.3 6.3e-71 237.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX91644.1 - 0.079 13.3 0.7 0.15 12.4 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX91645.1 - 0.0015 18.2 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF257 PF03192.13 EAX91647.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 DUF3839 PF12943.7 EAX91648.1 - 3.3e-153 508.1 12.5 4.2e-153 507.7 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX91648.1 - 0.024 15.0 0.2 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Tup N-terminal ZapB PF06005.12 EAX91648.1 - 1.7 9.2 4.8 3.8 8.0 0.1 2.8 3 0 0 3 3 3 0 Cell division protein ZapB PRD PF00874.20 EAX91648.1 - 1.7 9.0 7.7 1.7 9.0 0.1 3.4 4 1 1 5 5 5 0 PRD domain KELK PF15796.5 EAX91648.1 - 3.1 8.3 6.9 1.9 9.0 0.5 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAX91649.1 - 2.5e-147 488.8 14.5 3e-147 488.5 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91649.1 - 0.028 14.9 2.6 0.63 10.5 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX91649.1 - 0.24 11.7 3.5 13 6.2 0.0 3.6 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX91649.1 - 0.64 10.6 3.3 0.71 10.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) RasGEF PF00617.19 EAX91650.1 - 1.5e-16 61.1 0.1 7.5e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EAX91650.1 - 7.9e-05 22.9 0.2 0.00021 21.5 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif LisH_TPL PF17814.1 EAX91650.1 - 0.031 14.0 0.2 0.063 12.9 0.2 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain MitMem_reg PF13012.6 EAX91650.1 - 0.032 14.6 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4483 PF14825.6 EAX91651.1 - 1.3e-27 96.5 0.9 6.7e-16 58.4 0.2 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4483) DUF1295 PF06966.12 EAX91652.1 - 2.9e-26 92.4 0.1 3.2e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EAX91652.1 - 0.00012 22.1 0.1 0.00018 21.5 0.1 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EAX91652.1 - 0.00022 21.6 0.1 0.00034 21.0 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAX91652.1 - 0.013 15.9 0.5 0.096 13.1 0.5 2.1 1 1 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAX91652.1 - 0.061 12.1 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family IBD PF10416.9 EAX91654.1 - 8.2e-20 71.1 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PPP1R35_C PF15503.6 EAX91654.1 - 0.088 12.6 1.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Pox_polyA_pol_N PF12630.7 EAX91655.1 - 0.025 14.9 0.4 0.096 13.1 0.5 1.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain DUF3206 PF11472.8 EAX91655.1 - 0.051 13.6 0.3 0.18 11.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) Tn7_Tnp_TnsA_C PF08721.11 EAX91655.1 - 0.053 14.2 0.0 0.26 11.9 0.0 2.2 1 0 0 1 1 1 0 TnsA endonuclease C terminal UPF0086 PF01868.16 EAX91655.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function UPF0086 FliD_N PF02465.18 EAX91655.1 - 0.27 11.9 1.7 1.8 9.3 0.1 2.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.25 EAX91656.1 - 4e-15 55.9 0.0 6.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91656.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91656.1 - 0.0051 16.2 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 EAX91657.1 - 2.9e-10 40.0 0.3 2.9e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91657.1 - 0.0009 18.6 0.1 0.0009 18.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX91657.1 - 0.0033 16.4 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EAX91657.1 - 0.066 12.8 0.1 0.066 12.8 0.1 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 EAX91657.1 - 0.074 13.0 0.2 0.2 11.6 0.2 1.6 1 1 1 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF3839 PF12943.7 EAX91658.1 - 1.4e-151 502.7 10.9 1.9e-151 502.3 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX91658.1 - 0.035 14.5 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX91658.1 - 0.042 14.3 1.2 0.079 13.4 0.1 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX91658.1 - 0.21 12.1 6.2 2.2 8.8 0.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX91659.1 - 2.3e-35 120.8 0.3 6.3e-35 119.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain PapD_N PF00345.20 EAX91660.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX91660.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX91661.1 - 0.052 14.0 0.2 0.077 13.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX91662.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX91663.1 - 0.047 13.7 10.2 0.074 13.0 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RIX1 PF08167.12 EAX91666.1 - 0.0008 19.2 0.7 0.93 9.2 0.0 4.0 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis DUF4116 PF13475.6 EAX91666.1 - 0.19 11.5 3.5 4.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Prefoldin_2 PF01920.20 EAX91667.1 - 8.2e-16 57.9 6.7 9.9e-16 57.6 6.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EAX91667.1 - 0.00024 21.0 3.5 0.00036 20.4 3.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Paramyx_P_V_C PF03210.13 EAX91667.1 - 0.0059 16.4 1.7 0.018 14.8 0.2 2.1 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal ABC_tran_CTD PF16326.5 EAX91667.1 - 0.0061 16.8 6.2 0.48 10.7 0.1 2.2 2 0 0 2 2 2 2 ABC transporter C-terminal domain Spc7 PF08317.11 EAX91667.1 - 0.0066 15.4 5.3 0.41 9.5 0.4 2.0 2 0 0 2 2 2 2 Spc7 kinetochore protein Med9 PF07544.13 EAX91667.1 - 0.0069 16.4 4.0 0.3 11.2 1.0 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Macoilin PF09726.9 EAX91667.1 - 0.013 14.1 3.9 0.023 13.3 3.9 1.4 1 1 0 1 1 1 0 Macoilin family YscO PF07321.12 EAX91667.1 - 0.017 15.1 3.9 0.36 10.8 0.3 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO DUF4201 PF13870.6 EAX91667.1 - 0.026 14.3 3.9 0.91 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HR1 PF02185.16 EAX91667.1 - 0.026 14.6 6.1 0.093 12.9 0.5 2.6 3 0 0 3 3 3 0 Hr1 repeat TPR_MLP1_2 PF07926.12 EAX91667.1 - 0.036 14.1 6.0 0.29 11.2 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 EAX91667.1 - 0.05 13.6 3.6 0.4 10.7 0.5 2.1 2 0 0 2 2 2 0 Laminin Domain II Med4 PF10018.9 EAX91667.1 - 0.051 13.3 0.2 0.051 13.3 0.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FliJ PF02050.16 EAX91667.1 - 0.064 13.5 4.6 1.8 8.8 0.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Golgin_A5 PF09787.9 EAX91667.1 - 0.072 12.5 4.4 0.099 12.1 4.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 EAX91667.1 - 0.11 12.5 8.3 2 8.4 2.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EAX91667.1 - 0.11 12.6 7.2 1.3 9.2 7.2 2.0 1 1 0 1 1 1 0 Tropomyosin like FliD_C PF07195.12 EAX91667.1 - 0.13 11.6 4.2 0.058 12.8 1.0 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Osmo_CC PF08946.10 EAX91667.1 - 0.14 12.4 3.9 0.73 10.1 0.5 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Csm1_N PF18504.1 EAX91667.1 - 0.15 12.4 6.7 3.9 7.9 0.7 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain NPV_P10 PF05531.12 EAX91667.1 - 0.27 11.7 7.0 1.3e+02 3.1 7.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 EAX91667.1 - 0.33 10.1 1.7 0.37 10.0 0.4 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF4988 PF16378.5 EAX91667.1 - 0.45 10.2 3.7 2.4 7.8 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function SlyX PF04102.12 EAX91667.1 - 0.48 11.1 7.4 8.3 7.1 0.7 2.9 2 1 1 3 3 3 0 SlyX FlxA PF14282.6 EAX91667.1 - 0.49 10.4 11.9 0.21 11.6 1.8 2.6 2 1 1 3 3 3 0 FlxA-like protein Atg14 PF10186.9 EAX91667.1 - 0.88 8.6 4.4 12 4.8 4.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 EAX91667.1 - 1.1 9.8 6.8 84 3.7 6.8 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RasGAP_C PF03836.15 EAX91667.1 - 1.4 9.1 6.1 0.65 10.1 2.1 2.2 1 1 1 2 2 2 0 RasGAP C-terminus XhlA PF10779.9 EAX91667.1 - 3.1 8.1 8.1 1.5 9.0 1.1 2.4 2 1 0 2 2 2 0 Haemolysin XhlA ParA PF10609.9 EAX91668.1 - 1.7e-88 296.2 0.1 2e-88 296.0 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAX91668.1 - 8.7e-13 48.4 0.0 4.5e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAX91668.1 - 3.4e-09 36.9 0.7 7.3e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EAX91668.1 - 4.9e-06 26.0 0.2 6.6e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 EAX91668.1 - 7.8e-06 25.5 0.3 0.00024 20.6 0.3 2.3 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EAX91668.1 - 0.00011 22.1 0.7 0.061 13.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain VirC1 PF07015.11 EAX91668.1 - 0.00082 18.7 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.15 EAX91668.1 - 0.0011 18.2 3.4 0.02 14.1 0.3 2.9 2 1 1 3 3 3 1 Anion-transporting ATPase Pro_isomerase PF00160.21 EAX91669.1 - 1.1e-46 159.0 0.7 1.4e-46 158.7 0.7 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin PF00085.20 EAX91671.1 - 3.8e-21 75.0 0.0 4.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAX91671.1 - 4.5e-05 22.9 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAX91671.1 - 0.00032 21.1 0.0 0.00068 20.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX91671.1 - 0.00035 20.8 0.1 0.014 15.7 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EAX91671.1 - 0.0024 17.8 0.0 0.0035 17.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EAX91671.1 - 0.0032 17.6 0.0 0.015 15.5 0.0 1.9 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 EAX91671.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 EAX91671.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 EAX91671.1 - 0.031 14.0 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin KaiB PF07689.12 EAX91671.1 - 0.043 13.5 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 KaiB domain PepX_C PF08530.10 EAX91671.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain RNA_lig_T4_1 PF09511.10 EAX91673.1 - 0.068 13.0 0.2 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA ligase LRR_9 PF14580.6 EAX91674.1 - 2e-08 33.9 0.3 4.4e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EAX91674.1 - 8.9e-08 32.3 3.0 8.9e-08 32.3 3.0 2.9 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX91674.1 - 0.00028 20.6 4.8 0.0067 16.2 4.5 2.7 1 1 1 2 2 2 1 Leucine rich repeat Alanine_zipper PF11839.8 EAX91674.1 - 0.05 14.0 2.5 0.14 12.6 2.5 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DivIC PF04977.15 EAX91674.1 - 0.44 10.3 12.1 0.82 9.5 3.8 3.2 2 1 0 2 2 2 0 Septum formation initiator DUF5347 PF17282.2 EAX91674.1 - 0.57 10.5 7.5 0.73 10.2 1.1 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5347) Methyltransf_25 PF13649.6 EAX91675.1 - 1.5e-09 38.5 0.0 2.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX91675.1 - 2.5e-09 37.7 0.0 4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX91675.1 - 4.2e-06 26.6 0.1 6.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Trypan_PARP PF05887.11 EAX91675.1 - 0.0002 21.3 38.8 0.00033 20.6 38.8 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3788 PF12663.7 EAX91675.1 - 0.06 13.3 1.8 0.94 9.4 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3788) Methyltransf_12 PF08242.12 EAX91675.1 - 0.079 13.7 0.6 0.16 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EAX91675.1 - 0.097 12.0 0.3 0.33 10.3 0.2 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Zip PF02535.22 EAX91675.1 - 0.96 8.6 3.4 1 8.5 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 EAX91675.1 - 2.7 8.0 7.5 3.9 7.5 7.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 EAX91675.1 - 3.7 6.2 9.8 4.5 5.9 9.8 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EAX91675.1 - 4.1 6.1 7.6 6.3 5.5 7.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gly_rich PF12810.7 EAX91676.1 - 1.9e-36 126.2 21.8 2.3e-36 126.0 21.8 1.1 1 0 0 1 1 1 1 Glycine rich protein Peptidase_C13 PF01650.18 EAX91677.1 - 5.5e-47 160.4 0.2 9.7e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family IZUMO PF15005.6 EAX91677.1 - 0.12 12.8 0.4 8.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Ras PF00071.22 EAX91678.1 - 2.7e-07 30.3 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91678.1 - 0.00015 21.9 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 EAX91678.1 - 0.0005 19.0 0.0 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 EAX91678.1 - 0.052 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 EAX91678.1 - 0.085 12.8 0.3 0.47 10.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAX91678.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Aminotran_5 PF00266.19 EAX91679.1 - 6.8e-17 61.5 0.1 7.3e-16 58.1 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Spo12 PF05032.12 EAX91680.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pkinase PF00069.25 EAX91681.1 - 2.4e-66 223.8 0.0 2.8e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91681.1 - 1.9e-38 132.2 0.0 2.4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX91681.1 - 5e-05 22.4 0.6 0.00028 20.0 0.6 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX91681.1 - 0.00081 19.4 0.0 0.0018 18.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX91681.1 - 0.0018 17.7 0.0 0.0052 16.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like L_protein_N PF15518.6 EAX91681.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 L protein N-terminus Kdo PF06293.14 EAX91681.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX91681.1 - 0.15 11.6 0.5 0.57 9.7 0.2 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase C2 PF00168.30 EAX91682.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 C2 domain CK_II_beta PF01214.18 EAX91683.1 - 7.7e-47 159.4 3.0 9e-47 159.2 3.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Guanylate_cyc PF00211.20 EAX91684.1 - 2.7e-39 134.7 0.1 9.2e-39 132.9 0.1 1.9 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 EAX91684.1 - 0.0018 18.3 0.0 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 PAS domain Med30 PF11315.8 EAX91684.1 - 0.0056 16.9 2.9 0.075 13.2 0.1 3.2 2 1 1 3 3 3 1 Mediator complex subunit 30 PAS_9 PF13426.7 EAX91684.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 EAX91684.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF4381 PF14316.6 EAX91684.1 - 0.17 12.1 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ETRAMP PF09716.10 EAX91684.1 - 2 8.5 11.1 0.74 9.9 0.7 4.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Beta_helix PF13229.6 EAX91685.1 - 1.8e-05 24.7 5.3 0.00028 20.8 0.3 2.3 1 1 0 2 2 2 2 Right handed beta helix region LapA_dom PF06305.11 EAX91685.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain OAD_gamma PF04277.13 EAX91685.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ank_2 PF12796.7 EAX91686.1 - 4.1e-77 254.8 26.1 2.1e-15 57.1 0.6 9.4 2 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91686.1 - 4.4e-77 253.5 18.9 1.9e-10 41.0 0.0 14.0 4 1 9 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91686.1 - 7.7e-68 216.4 20.7 2.6e-05 24.3 0.1 14.7 16 0 0 16 16 16 11 Ankyrin repeat Ank PF00023.30 EAX91686.1 - 2e-67 220.9 22.9 6.1e-07 29.6 0.3 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EAX91686.1 - 1.4e-65 216.4 10.1 1.4e-10 41.2 0.1 9.6 4 2 4 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91686.1 - 8.2e-29 99.4 6.5 8.2e-29 99.4 6.5 5.4 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAX91686.1 - 0.0031 17.2 0.2 0.27 10.8 0.0 2.6 2 1 0 2 2 2 1 Coiled coil protein 84 CEP44 PF15007.6 EAX91686.1 - 0.021 15.0 0.3 11 6.2 0.0 4.8 4 2 0 4 4 4 0 Centrosomal spindle body, CEP44 PH_8 PF15409.6 EAX91686.1 - 0.053 13.8 0.3 1.3e+02 2.9 0.0 4.7 3 2 2 5 5 5 0 Pleckstrin homology domain IU_nuc_hydro PF01156.19 EAX91687.1 - 4.7e-68 230.0 0.0 5.2e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ras PF00071.22 EAX91688.1 - 6.9e-39 133.1 0.0 7.9e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91688.1 - 1.5e-28 99.5 0.0 2.2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91688.1 - 8.1e-14 51.4 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX91688.1 - 5.8e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX91688.1 - 6.2e-05 22.5 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX91688.1 - 0.00019 21.4 0.0 0.14 12.1 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX91688.1 - 0.00023 21.2 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sacchrp_dh_NADP PF03435.18 EAX91688.1 - 0.0059 16.9 0.1 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FeoB_N PF02421.18 EAX91688.1 - 0.029 13.9 0.1 1.3 8.5 0.1 3.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 EAX91688.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 EAX91688.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glucokinase PF02685.16 EAX91689.1 - 3.1e-22 79.0 0.0 4.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EAX91689.1 - 0.00039 20.0 0.0 0.077 12.5 0.0 2.3 2 1 0 2 2 2 2 ROK family SPC25 PF06703.11 EAX91690.1 - 3.2 7.5 11.3 13 5.5 0.4 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Maf1 PF09174.10 EAX91691.1 - 2.4e-19 70.1 2.6 3.3e-19 69.7 2.6 1.3 1 1 0 1 1 1 1 Maf1 regulator FANCI_HD1 PF14679.6 EAX91691.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 Sec3_C_2 PF15278.6 EAX91692.1 - 0.048 14.0 0.1 0.048 14.0 0.1 4.1 3 2 1 4 4 4 0 Sec3 exocyst complex subunit FAM184 PF15665.5 EAX91692.1 - 0.23 11.2 60.3 5.8 6.6 48.4 3.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 EAX91692.1 - 0.84 8.5 63.0 0.26 10.1 16.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAX91692.1 - 0.94 9.5 67.9 0.86 9.7 23.1 4.5 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Nudc_N PF14050.6 EAX91693.1 - 0.02 14.9 0.2 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF1547 PF07577.11 EAX91693.1 - 0.075 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) OCD_Mu_crystall PF02423.15 EAX91694.1 - 3.1e-54 184.0 0.2 3.8e-54 183.8 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EAX91694.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EAX91694.1 - 0.0037 16.6 0.0 0.0081 15.5 0.0 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CBP4 PF07960.11 EAX91695.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 CBP4 XPC-binding PF09280.11 EAX91695.1 - 0.015 15.0 0.2 0.028 14.2 0.2 1.6 1 0 0 1 1 1 0 XPC-binding domain DUF2452 PF10504.9 EAX91695.1 - 0.033 13.7 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Ank_2 PF12796.7 EAX91696.1 - 1e-215 699.0 0.4 4.4e-21 75.3 0.0 9.3 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX91696.1 - 8.8e-119 386.0 0.0 2.1e-10 40.7 0.0 15.1 1 1 14 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 EAX91696.1 - 3.4e-112 362.5 0.0 4e-07 30.2 0.0 15.7 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 EAX91696.1 - 4.3e-96 314.2 0.0 1.4e-10 41.5 0.0 12.4 8 5 7 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91696.1 - 4.2e-90 284.8 0.0 0.00013 22.1 0.0 15.4 15 0 0 15 15 15 15 Ankyrin repeat zf-RNPHF PF08080.12 EAX91696.1 - 0.015 15.2 0.1 19 5.3 0.0 5.0 6 0 0 6 6 6 0 RNPHF zinc finger DUF4515 PF14988.6 EAX91696.1 - 0.048 13.5 2.5 0.081 12.8 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) FBD PF08387.10 EAX91696.1 - 1.9 8.4 17.6 31 4.6 0.0 8.6 8 4 2 11 11 10 0 FBD Ank_5 PF13857.6 EAX91698.1 - 0.00022 21.5 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX91698.1 - 0.00044 20.8 0.0 0.00053 20.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91698.1 - 0.00074 20.1 0.0 0.00088 19.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91698.1 - 0.019 15.4 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat PC_rep PF01851.22 EAX91699.1 - 7.9e-27 92.3 5.3 1.2e-09 38.1 0.2 6.9 6 0 0 6 6 6 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EAX91699.1 - 1.8e-20 73.1 0.0 2.8e-11 43.6 0.1 4.1 2 1 3 5 5 5 5 HEAT repeats RPN2_C PF18004.1 EAX91699.1 - 5.2e-19 68.7 0.1 6.7e-10 39.1 0.1 2.3 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1702 PF08012.11 EAX91699.1 - 0.0026 16.7 0.0 0.005 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1702) HEAT_EZ PF13513.6 EAX91699.1 - 0.0098 16.4 7.9 0.73 10.4 0.3 5.2 4 2 1 5 5 5 2 HEAT-like repeat HrpB1_HrpK PF09613.10 EAX91699.1 - 0.024 14.3 0.2 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Cnd1 PF12717.7 EAX91699.1 - 0.044 13.8 0.2 8.3 6.4 0.1 2.7 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF1770 PF08589.10 EAX91699.1 - 0.063 14.2 1.2 0.14 13.1 1.2 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) HEAT_PBS PF03130.16 EAX91699.1 - 9.3 7.2 8.1 5.3 8.0 0.1 3.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Ank_4 PF13637.6 EAX91700.1 - 1.1e-115 376.7 47.1 3.3e-11 43.5 0.2 19.8 7 3 14 21 21 21 19 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX91700.1 - 9.8e-110 359.4 45.2 9.9e-15 54.9 3.2 12.2 3 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91700.1 - 1.2e-108 351.2 34.9 8.5e-06 26.0 0.1 20.6 21 0 0 21 21 21 19 Ankyrin repeat Ank_3 PF13606.6 EAX91700.1 - 3.6e-83 263.5 36.5 3.2e-05 24.0 0.0 21.6 22 1 0 22 22 22 17 Ankyrin repeat Ank_5 PF13857.6 EAX91700.1 - 4.1e-79 259.6 29.9 8.5e-08 32.3 0.4 16.6 6 3 14 20 20 20 18 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91700.1 - 3.7e-29 100.5 34.8 1.7e-28 98.4 3.2 7.7 7 2 1 8 8 8 3 Domain of unknown function (DUF3447) DUF4796 PF16044.5 EAX91700.1 - 0.0033 17.0 3.1 0.98 9.0 0.1 5.0 3 1 3 6 6 6 1 Domain of unknown function (DUF4796) DUF5334 PF17268.2 EAX91700.1 - 0.16 12.3 0.3 50 4.3 0.0 4.0 3 1 1 4 4 4 0 Family of unknown function (DUF5334) CCDC84 PF14968.6 EAX91700.1 - 0.71 9.4 3.0 8.9 5.8 0.0 3.3 2 1 0 3 3 3 0 Coiled coil protein 84 DUF3718 PF12514.8 EAX91700.1 - 1.1 9.5 4.3 6.6 7.0 0.1 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF3718) RL PF17797.1 EAX91700.1 - 1.6 8.7 6.1 2.5 8.1 0.0 4.0 4 0 0 4 4 4 0 RL domain MMR_HSR1_Xtn PF16897.5 EAX91702.1 - 2e-30 104.9 1.7 2.2e-30 104.8 0.5 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAX91702.1 - 1.3e-21 76.8 0.0 3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EAX91702.1 - 8.5e-17 61.0 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EAX91702.1 - 7.1e-11 41.9 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAX91702.1 - 2.7e-05 24.3 0.8 0.022 14.8 0.2 2.6 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 EAX91702.1 - 0.0059 15.6 0.2 0.029 13.4 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EAX91702.1 - 0.048 14.2 0.1 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EAX91702.1 - 0.11 12.4 0.1 0.44 10.4 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 EAX91702.1 - 0.12 12.6 0.4 0.5 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain KicB PF03882.14 EAX91703.1 - 0.071 13.3 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 MukF winged-helix domain SirB PF04247.12 EAX91704.1 - 0.19 11.8 4.9 0.45 10.6 0.3 2.5 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Aurora-A_bind PF09041.10 EAX91705.1 - 0.078 13.1 1.9 0.14 12.2 1.9 1.5 1 0 0 1 1 1 0 Aurora-A binding Podoplanin PF05808.11 EAX91706.1 - 0.0012 18.9 1.8 0.0024 18.0 1.8 1.5 1 0 0 1 1 1 1 Podoplanin PQ-loop PF04193.14 EAX91708.1 - 6.5e-17 61.0 11.1 2.4e-11 43.2 1.4 2.8 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EAX91708.1 - 0.042 14.7 1.5 0.042 14.7 1.5 2.5 3 0 0 3 3 3 0 ER lumen protein retaining receptor DUF5412 PF17428.2 EAX91708.1 - 0.068 13.0 0.1 0.068 13.0 0.1 3.0 4 1 0 4 4 4 0 Family of unknown function (DUF5412) Ribosomal_S28e PF01200.18 EAX91709.1 - 6.2e-31 106.2 2.9 7.1e-31 106.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e LRR_4 PF12799.7 EAX91711.1 - 1.5e-08 34.7 20.0 8.3e-05 22.9 3.2 4.9 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX91711.1 - 0.00014 21.9 9.4 4.2 8.3 0.2 6.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 EAX91711.1 - 0.0036 17.0 10.4 0.44 10.4 1.3 4.9 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EAX91711.1 - 0.11 12.6 10.6 14 6.1 0.4 6.0 6 0 0 6 6 6 0 Leucine Rich repeat Hamartin PF04388.12 EAX91711.1 - 3.4 6.2 12.4 5.1 5.6 12.4 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4367 PF14285.6 EAX91713.1 - 0.0048 17.3 3.8 0.0092 16.4 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4367) Rxt3 PF08642.10 EAX91713.1 - 0.0074 17.1 0.0 0.02 15.7 0.0 1.7 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 DUF2321 PF10083.9 EAX91713.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) BLOC1_2 PF10046.9 EAX91714.1 - 0.00014 22.1 9.1 0.00014 22.1 9.1 4.9 4 1 1 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 EAX91714.1 - 0.016 15.3 8.4 0.016 15.3 8.4 6.7 7 1 0 7 7 7 0 bZIP transcription factor SLATT_6 PF18169.1 EAX91714.1 - 5.4 6.6 6.8 1.9 8.1 3.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Amidohydro_1 PF01979.20 EAX91715.1 - 5.8e-25 88.3 0.1 1.9e-24 86.6 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAX91715.1 - 4.4e-15 56.1 2.0 4.6e-06 26.4 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase family GAF PF01590.26 EAX91716.1 - 3.9e-07 30.8 0.0 0.0051 17.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EAX91716.1 - 7e-06 26.4 0.0 0.07 13.4 0.0 3.1 3 0 0 3 3 3 2 GAF domain Aa_trans PF01490.18 EAX91718.1 - 1.4e-06 27.3 30.2 1.9e-06 26.8 30.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2754 PF10953.8 EAX91718.1 - 0.61 10.4 4.2 1.7 9.0 1.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF1146 PF06612.11 EAX91719.1 - 0.046 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5617 PF18493.1 EAX91719.1 - 0.085 13.0 1.0 0.33 11.1 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) GPS2_interact PF15784.5 EAX91720.1 - 0.088 13.3 1.2 0.12 12.9 1.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91720.1 - 0.14 11.1 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX91721.1 - 0.11 12.4 12.3 0.13 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91721.1 - 0.59 10.6 5.8 0.66 10.4 5.8 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4107 PF13389.6 EAX91723.1 - 2.4e-65 219.6 1.0 3.3e-65 219.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX91723.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PfkB PF00294.24 EAX91724.1 - 1.3e-43 149.4 0.0 1.8e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ras PF00071.22 EAX91725.1 - 5.4e-36 123.6 0.0 6.4e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91725.1 - 1.1e-30 106.3 0.0 1.2e-29 103.0 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91725.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX91725.1 - 1.8e-06 27.5 0.0 6.6e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX91725.1 - 3.4e-05 23.8 0.2 0.012 15.5 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX91725.1 - 3.5e-05 23.9 0.0 6.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EAX91725.1 - 0.00077 18.8 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 EAX91725.1 - 0.0012 19.2 0.0 0.0014 19.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EAX91725.1 - 0.0031 17.2 0.0 0.0076 16.0 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX91725.1 - 0.0076 16.0 0.1 0.049 13.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Cas_Cas02710 PF09670.10 EAX91725.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) AAA PF00004.29 EAX91725.1 - 0.014 15.8 0.0 0.053 14.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAX91725.1 - 0.017 14.3 0.0 0.045 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRPRB PF09439.10 EAX91725.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAX91725.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAX91725.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAX91725.1 - 0.067 13.2 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EAX91725.1 - 0.091 12.5 0.4 14 5.4 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EAX91725.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAX91725.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RAB3GAP2_N PF14655.6 EAX91726.1 - 2.1e-21 76.7 0.0 1.6e-18 67.2 0.0 2.6 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ank_2 PF12796.7 EAX91727.1 - 6.4e-20 71.5 0.2 5.1e-07 30.2 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91727.1 - 2.9e-18 66.0 1.8 0.00041 20.8 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX91727.1 - 1.1e-14 54.2 0.8 6.5e-07 29.5 0.6 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91727.1 - 8.2e-13 47.3 2.0 0.0078 16.6 0.2 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAX91727.1 - 4.8e-11 42.6 0.1 0.0021 18.4 0.2 5.8 5 1 0 5 5 5 3 Ankyrin repeat DUF3839 PF12943.7 EAX91728.1 - 8.7e-70 234.9 5.0 1.1e-69 234.5 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX91728.1 - 0.01 15.9 0.1 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FKBP_N PF01346.18 EAX91728.1 - 0.034 15.1 0.3 0.061 14.3 0.3 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase APC_u14 PF16635.5 EAX91728.1 - 0.074 13.6 2.3 0.14 12.7 2.3 1.4 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr ZapB PF06005.12 EAX91728.1 - 0.22 12.0 1.2 0.89 10.0 0.1 2.3 3 0 0 3 3 3 0 Cell division protein ZapB T5orf172 PF10544.9 EAX91729.1 - 5.6e-05 23.6 0.4 0.00016 22.2 0.4 1.8 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX91729.1 - 0.016 15.1 0.1 0.078 12.8 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain DUF4107 PF13389.6 EAX91730.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX91731.1 - 0.024 14.3 0.1 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX91732.1 - 1.9e-156 518.7 12.2 2.4e-156 518.3 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX91732.1 - 1.5 9.3 4.4 1.6 9.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX91732.1 - 4.1 7.9 6.0 4.8 7.7 0.1 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX91734.1 - 5.5e-42 142.2 0.1 5.5e-42 142.2 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX91735.1 - 4.5e-30 104.9 13.4 3.2e-29 102.1 13.4 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX91735.1 - 0.041 13.9 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX91737.1 - 0.024 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX91737.1 - 0.084 12.9 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX91737.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX91738.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Trypan_PARP PF05887.11 EAX91739.1 - 0.033 14.2 8.5 0.051 13.6 8.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91739.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX91740.1 - 0.13 11.2 0.1 0.13 11.3 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MULE PF10551.9 EAX91742.1 - 1.4e-10 41.4 1.5 2.4e-10 40.7 1.5 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX91742.1 - 0.0013 18.8 1.8 0.0048 17.0 1.8 2.0 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX91742.1 - 0.0041 16.0 0.6 0.0062 15.4 0.6 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Peptidase_M8 PF01457.16 EAX91743.1 - 1.5e-27 96.5 0.1 2.2e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 Leishmanolysin Mid2 PF04478.12 EAX91743.1 - 0.0023 17.8 0.1 0.0048 16.8 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX91743.1 - 0.0039 17.2 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF1180 PF06679.12 EAX91743.1 - 0.0047 17.3 0.2 0.0097 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Phage_holin_3_6 PF07332.11 EAX91743.1 - 0.13 12.3 0.8 0.22 11.6 0.8 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Protocadherin PF08374.11 EAX91743.1 - 0.19 11.7 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 Protocadherin Pyr_excise PF03013.14 EAX91746.1 - 0.051 13.6 0.2 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 Pyrimidine dimer DNA glycosylase Myb_DNA-binding PF00249.31 EAX91747.1 - 3.1e-32 110.5 6.9 1.7e-16 60.1 2.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91747.1 - 1.3e-29 102.2 2.2 9.3e-17 61.0 0.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91747.1 - 9.9e-05 22.3 0.0 0.076 13.0 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91747.1 - 0.0019 18.1 1.0 0.1 12.5 0.1 2.4 2 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX91747.1 - 0.0037 17.4 0.8 0.09 13.0 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX91747.1 - 0.0058 16.7 0.7 2.3 8.3 0.2 2.2 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Methyltrans_RNA PF04452.14 EAX91747.1 - 0.0076 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Myb_DNA-bind_4 PF13837.6 EAX91747.1 - 0.0098 16.3 8.1 0.44 10.9 2.5 3.7 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain CAF1 PF04857.20 EAX91748.1 - 0.011 15.0 0.9 0.011 15.0 0.9 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease Syntaxin_2 PF14523.6 EAX91748.1 - 0.014 15.8 13.7 0.24 11.8 0.5 2.9 2 1 1 3 3 3 0 Syntaxin-like protein CagA PF03507.13 EAX91748.1 - 0.014 15.3 1.4 0.03 14.3 1.4 1.5 1 0 0 1 1 1 0 CagA exotoxin ABC_tran_CTD PF16326.5 EAX91748.1 - 0.015 15.5 22.0 0.09 13.0 0.8 3.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain MCD_N PF17408.2 EAX91748.1 - 0.026 14.7 1.6 2.8 8.2 0.1 3.1 1 1 2 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain AATF-Che1 PF13339.6 EAX91748.1 - 0.035 14.8 13.5 0.49 11.1 13.4 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Spectrin PF00435.21 EAX91748.1 - 0.082 13.4 12.4 0.1 13.1 0.8 3.8 1 1 1 2 2 2 0 Spectrin repeat Feld-I_B PF09252.10 EAX91748.1 - 0.085 12.8 0.3 0.22 11.5 0.2 1.8 1 1 0 1 1 1 0 Allergen Fel d I-B chain DUF2430 PF10353.9 EAX91748.1 - 0.14 12.6 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) ZnuA PF01297.17 EAX91748.1 - 0.68 9.3 5.1 1.6 8.1 5.0 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF948 PF06103.11 EAX91748.1 - 0.79 10.0 3.1 5.9 7.2 1.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3510 PF12022.8 EAX91748.1 - 1 9.7 9.1 0.066 13.6 3.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Topoisom_I_N PF02919.15 EAX91748.1 - 1.1 8.7 10.3 0.63 9.5 7.2 1.8 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Ly49 PF08391.10 EAX91748.1 - 1.7 9.0 14.6 0.063 13.6 6.2 2.2 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region PIN_8 PF18476.1 EAX91748.1 - 2.7 7.8 12.6 2.8 7.7 11.7 1.4 1 1 0 1 1 1 0 PIN like domain DUF4407 PF14362.6 EAX91748.1 - 3.5 6.9 8.9 5.2 6.3 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tweety PF04906.13 EAX91749.1 - 0.07 11.8 0.2 0.097 11.3 0.2 1.1 1 0 0 1 1 1 0 Tweety DUF1664 PF07889.12 EAX91749.1 - 0.099 12.7 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF241 PF03087.14 EAX91749.1 - 0.2 11.5 2.0 0.26 11.1 2.0 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Rap_GAP PF02145.15 EAX91750.1 - 2.7e-40 137.9 0.1 2.7e-40 137.9 0.1 2.4 2 0 0 2 2 2 1 Rap/ran-GAP LIM PF00412.22 EAX91751.1 - 7.4e-22 77.3 76.0 1.3e-09 38.1 6.6 4.4 4 0 0 4 4 4 4 LIM domain RRM_1 PF00076.22 EAX91752.1 - 8.3e-16 57.6 0.2 1.2e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EAX91752.1 - 0.00025 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ank_4 PF13637.6 EAX91753.1 - 4.1e-11 43.2 0.9 3.6e-07 30.6 0.0 4.2 6 0 0 6 6 6 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91753.1 - 1.1e-09 38.1 0.9 1.1e-09 38.1 0.9 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX91753.1 - 3.9e-09 37.0 1.2 1.3e-06 28.9 0.1 3.4 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91753.1 - 3.3e-06 27.0 1.1 0.16 12.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX91753.1 - 0.013 15.8 0.0 0.95 9.9 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ACDC PF14733.6 EAX91753.1 - 0.066 13.5 0.3 0.066 13.5 0.3 2.8 3 0 0 3 3 3 0 AP2-coincident C-terminal VASt PF16016.5 EAX91753.1 - 0.11 12.9 0.1 1 9.7 0.1 2.3 1 1 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain DUF4108 PF13390.6 EAX91755.1 - 3.1e-63 212.0 6.1 3.5e-63 211.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX91756.1 - 1.4e-06 27.9 1.6 1.4e-06 27.9 1.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX91756.1 - 3.4e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX91756.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX91756.1 - 0.00017 21.7 3.4 0.0004 20.4 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91756.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX91756.1 - 0.0019 18.1 0.7 0.0047 16.7 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX91756.1 - 0.002 17.8 0.5 0.012 15.3 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX91756.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX91756.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX91756.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX91756.1 - 0.093 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX91756.1 - 0.33 11.4 3.7 0.66 10.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX91756.1 - 0.39 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PTR PF12789.7 EAX91757.1 - 3.2e-24 84.7 9.8 3.2e-24 84.7 9.8 4.8 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX91757.1 - 0.054 13.2 1.0 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) RhoGEF PF00621.20 EAX91759.1 - 6.7e-27 94.9 2.7 6.7e-27 94.9 2.7 2.1 1 1 1 2 2 2 1 RhoGEF domain DUF5037 PF16440.5 EAX91759.1 - 0.032 13.8 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) Cpta_toxin PF07254.12 EAX91760.1 - 0.056 13.4 1.2 0.11 12.5 0.6 1.9 1 1 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system DAGK_prokar PF01219.19 EAX91760.1 - 1.5 8.7 7.1 0.24 11.2 1.0 2.4 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase SLC12 PF03522.15 EAX91761.1 - 2e-25 89.7 0.0 1.4e-12 47.4 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 Viral_DNA_bi PF02236.17 EAX91761.1 - 0.12 12.6 0.0 0.68 10.2 0.0 2.3 1 1 1 2 2 2 0 Viral DNA-binding protein, all alpha domain Peptidase_C39 PF03412.15 EAX91761.1 - 0.15 11.9 0.3 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C39 family PSP PF04046.16 EAX91764.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91765.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat EGF_2 PF07974.13 EAX91767.1 - 7.6 7.0 14.5 15 6.0 0.6 2.6 2 0 0 2 2 2 0 EGF-like domain DHHC PF01529.20 EAX91768.1 - 6.2e-23 81.4 8.7 1.6e-22 80.0 1.8 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase Wzy_C PF04932.15 EAX91768.1 - 0.0056 16.3 2.5 0.0056 16.3 2.5 1.7 2 0 0 2 2 2 1 O-Antigen ligase Tetraspanin PF00335.20 EAX91768.1 - 0.064 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 EAX91768.1 - 0.073 11.8 8.6 0.047 12.5 2.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CPSF_A PF03178.15 EAX91770.1 - 2.4e-16 60.0 0.3 4.6e-16 59.0 0.3 1.4 1 0 0 1 1 1 1 CPSF A subunit region FmdE PF02663.14 EAX91771.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon M16C_assoc PF08367.11 EAX91772.1 - 8e-24 84.1 0.0 1.8e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAX91772.1 - 6.6e-12 45.8 1.7 5.3e-06 26.6 0.2 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAX91772.1 - 4.8e-07 29.9 2.0 5.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Csa1 PF06023.12 EAX91772.1 - 0.054 12.8 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Anp1 PF03452.14 EAX91772.1 - 0.061 12.7 1.2 6.3 6.1 0.4 2.4 2 0 0 2 2 2 0 Anp1 Helicase_C PF00271.31 EAX91772.1 - 0.082 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Tipalpha PF16753.5 EAX91772.1 - 0.083 12.7 0.4 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter DUSP PF06337.12 EAX91772.1 - 0.67 10.6 2.7 23 5.7 0.0 3.6 3 1 0 3 3 3 0 DUSP domain DUF3839 PF12943.7 EAX91774.1 - 1.5e-154 512.5 11.2 1.8e-154 512.2 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91774.1 - 7 7.2 7.2 4.5 7.8 0.3 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HEAT PF02985.22 EAX91775.1 - 0.079 13.3 0.0 12 6.5 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat SNF2_N PF00176.23 EAX91776.1 - 2.4e-47 161.4 0.0 4e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX91776.1 - 2.1e-11 44.1 0.1 7.7e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PglZ PF08665.12 EAX91776.1 - 0.096 12.8 0.3 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 PglZ domain CRIM PF16978.5 EAX91778.1 - 0.052 13.7 0.8 0.088 13.0 0.2 1.6 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain Chlam_PMP PF02415.17 EAX91778.1 - 0.11 13.0 43.9 3.4 8.3 2.7 9.3 9 1 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glug PF07581.12 EAX91778.1 - 3.6 8.2 8.7 33 5.2 0.3 4.3 3 1 1 4 4 4 0 The GLUG motif CK2S PF15011.6 EAX91780.1 - 0.077 12.9 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate AIG1 PF04548.16 EAX91782.1 - 3e-17 62.7 0.2 7.4e-17 61.4 0.1 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 EAX91782.1 - 0.00024 21.2 0.0 0.0005 20.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PA_decarbox PF05870.11 EAX91782.1 - 0.031 13.9 0.7 0.072 12.7 0.7 1.6 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) AAA_7 PF12775.7 EAX91782.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_10 PF12846.7 EAX91782.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 EAX91782.1 - 0.099 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lipin_mid PF16876.5 EAX91782.1 - 0.71 10.0 2.9 4.4 7.5 0.5 2.3 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain AIG1 PF04548.16 EAX91783.1 - 5.9e-22 78.0 1.5 7.1e-22 77.8 1.5 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EAX91783.1 - 2.5e-09 37.2 0.7 5.5e-09 36.1 0.6 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX91783.1 - 8.3e-05 22.6 0.8 0.0004 20.3 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EAX91783.1 - 0.00022 21.3 5.7 0.016 15.3 4.8 2.8 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 EAX91783.1 - 0.0013 18.1 2.8 0.0017 17.7 0.3 2.1 2 0 0 2 2 2 1 Septin Glyco_transf_7N PF13733.6 EAX91783.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 SRPRB PF09439.10 EAX91783.1 - 0.029 13.8 0.8 0.06 12.8 0.7 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX91783.1 - 0.064 12.8 0.6 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 EAX91783.1 - 0.14 12.7 4.4 0.27 11.7 4.4 1.8 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.17 EAX91783.1 - 4.1 7.4 7.5 98 2.9 7.5 2.7 1 1 0 1 1 1 0 Helicase HerA, central domain DUF1796 PF08795.10 EAX91784.1 - 0.12 12.4 6.2 2.6 8.0 0.0 4.4 4 2 0 4 4 4 0 Putative papain-like cysteine peptidase (DUF1796) PMT PF02366.18 EAX91786.1 - 2.7e-38 131.9 9.4 2.7e-38 131.9 9.4 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX91786.1 - 1.1e-19 70.9 15.3 2.7e-18 66.3 15.3 2.7 1 1 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase Glyco_hydro_16 PF00722.21 EAX91787.1 - 1.6e-12 47.2 6.4 2.4e-10 40.2 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Orf78 PF06024.12 EAX91787.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 EAX91787.1 - 0.0021 18.0 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EAX91787.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR_5 PF13306.6 EAX91788.1 - 5.9e-64 213.8 58.3 1.6e-21 76.6 2.3 5.3 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX91788.1 - 2.3e-15 56.1 2.1 0.00011 21.9 0.0 7.5 5 1 5 10 10 10 5 Leucine rich repeat LRR_4 PF12799.7 EAX91788.1 - 0.00027 21.3 7.1 23 5.6 0.0 7.0 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) Sigma_reg_N PF13800.6 EAX91788.1 - 0.12 12.7 2.4 3.6 7.9 0.1 3.6 4 0 0 4 4 4 0 Sigma factor regulator N-terminal AAA_23 PF13476.6 EAX91789.1 - 5.9e-17 62.8 7.8 5.9e-17 62.8 7.8 6.5 2 2 3 5 5 2 1 AAA domain SMC_N PF02463.19 EAX91789.1 - 2.9e-13 49.8 47.3 2.6e-12 46.7 47.3 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAX91789.1 - 1e-05 25.5 71.1 4.8e-05 23.2 32.7 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EAX91789.1 - 4.6e-05 23.1 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 EAX91789.1 - 0.00015 21.2 17.6 0.00015 21.2 17.6 6.1 3 2 2 5 5 5 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EAX91789.1 - 0.00048 19.1 96.4 0.0019 17.2 15.0 5.7 2 2 4 6 6 6 3 Spc7 kinetochore protein EzrA PF06160.12 EAX91789.1 - 0.0012 17.2 83.0 0.033 12.4 11.0 4.6 2 2 2 4 4 4 3 Septation ring formation regulator, EzrA DUF1664 PF07889.12 EAX91789.1 - 0.0012 18.9 1.4 0.0012 18.9 1.4 7.2 3 2 3 6 6 6 3 Protein of unknown function (DUF1664) AAA_21 PF13304.6 EAX91789.1 - 0.0025 17.7 2.9 0.0025 17.7 2.9 4.0 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ZapB PF06005.12 EAX91789.1 - 0.003 18.0 4.2 0.003 18.0 4.2 8.9 5 2 1 6 6 4 1 Cell division protein ZapB ATG16 PF08614.11 EAX91789.1 - 0.0047 17.2 24.3 0.0047 17.2 24.3 5.3 2 2 2 4 4 3 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 EAX91789.1 - 0.01 15.9 59.8 0.021 14.8 4.7 6.9 3 2 4 7 7 7 0 Laminin Domain II Spectrin PF00435.21 EAX91789.1 - 0.011 16.1 9.6 0.011 16.1 9.6 7.0 3 2 3 7 7 6 0 Spectrin repeat ABC_tran PF00005.27 EAX91789.1 - 0.13 12.7 0.1 0.13 12.7 0.1 6.1 3 2 1 4 4 3 0 ABC transporter TPR_MLP1_2 PF07926.12 EAX91789.1 - 0.55 10.3 95.6 0.076 13.1 3.6 7.7 4 2 3 7 7 7 0 TPR/MLP1/MLP2-like protein RsgA_GTPase PF03193.16 EAX91789.1 - 0.9 9.4 4.7 3.1 7.7 0.1 3.4 2 0 0 2 2 2 0 RsgA GTPase MukB PF04310.12 EAX91789.1 - 1.3 8.8 0.0 1.3 8.8 0.0 4.3 3 1 0 4 4 4 0 MukB N-terminal Baculo_PEP_C PF04513.12 EAX91789.1 - 2.4 8.2 37.4 0.11 12.5 5.4 5.4 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 EAX91789.1 - 2.6 8.1 90.2 0.096 12.7 1.7 6.3 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 EAX91789.1 - 5.9 7.4 43.7 0.077 13.5 4.3 7.1 6 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF563 PF04577.14 EAX91790.1 - 5.7e-30 105.0 0.2 1.1e-29 104.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MULE PF10551.9 EAX91791.1 - 1.9e-11 44.2 0.0 3.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAX91791.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 PWI domain DUF3781 PF12636.7 EAX91792.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX91793.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91793.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX91794.1 - 0.092 12.7 7.6 0.14 12.1 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX91795.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX91796.1 - 0.016 15.6 0.5 0.017 15.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX91797.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX91799.1 - 8.9e-156 516.5 11.7 1.1e-155 516.1 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91799.1 - 0.84 10.1 5.0 1.9 9.0 0.7 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX91800.1 - 1.1e-19 70.3 0.3 2e-19 69.5 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX91800.1 - 0.026 14.5 2.5 0.064 13.2 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pox_A32 PF04665.12 EAX91800.1 - 0.057 12.9 0.4 0.091 12.2 0.4 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Amidase02_C PF12123.8 EAX91801.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91802.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1493 PF07377.12 EAX91804.1 - 0.077 13.5 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91805.1 - 0.049 14.2 4.8 12 7.1 0.2 3.4 3 1 0 3 3 3 0 TMP repeat ubiquitin PF00240.23 EAX91806.1 - 2.3e-07 30.5 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DiSB-ORF2_chro PF16506.5 EAX91806.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative virion glycoprotein of insect viruses DUF2407 PF10302.9 EAX91806.1 - 0.078 13.5 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TLD PF07534.16 EAX91807.1 - 6.4e-38 130.1 0.8 9.5e-38 129.6 0.8 1.3 1 0 0 1 1 1 1 TLD LysM PF01476.20 EAX91807.1 - 8.3e-09 35.4 1.6 2e-08 34.1 0.1 2.4 3 0 0 3 3 3 1 LysM domain Cnn_1N PF07989.11 EAX91809.1 - 0.01 15.9 5.1 0.01 15.9 5.1 9.0 4 4 3 7 7 7 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EAX91809.1 - 0.1 11.4 84.4 0.017 14.0 12.8 6.1 3 2 3 6 6 6 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAX91809.1 - 4.4 7.4 78.0 0.24 11.4 4.3 7.2 4 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein ARL2_Bind_BART PF11527.8 EAX91810.1 - 9.6e-22 77.3 5.2 1.3e-21 76.9 5.2 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Adaptin_N PF01602.20 EAX91811.1 - 2.3e-63 214.6 18.8 2.7e-63 214.3 18.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EAX91811.1 - 3.8e-17 62.6 0.3 7.1e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EAX91811.1 - 0.00047 20.5 0.9 0.16 12.4 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.8 EAX91811.1 - 0.056 13.6 3.6 0.059 13.5 0.2 2.8 3 0 0 3 3 3 0 V-ATPase subunit H GRIP PF01465.20 EAX91811.1 - 0.071 13.0 0.6 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 GRIP domain Myb_DNA-binding PF00249.31 EAX91812.1 - 6.4e-28 96.7 2.7 2.5e-14 53.2 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91812.1 - 3.5e-24 84.8 9.1 2.4e-17 62.9 0.6 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX91812.1 - 1.9e-06 27.7 3.8 0.00019 21.3 1.5 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX91812.1 - 0.001 19.1 2.2 0.77 9.8 0.0 2.4 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX91812.1 - 0.019 15.1 0.0 2.2 8.4 0.0 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EAX91812.1 - 0.029 14.6 1.4 0.2 11.9 0.5 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF4177 PF13783.6 EAX91812.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Myb_DNA-bind_4 PF13837.6 EAX91812.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2407 PF10302.9 EAX91813.1 - 0.0038 17.8 0.0 0.0059 17.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EAX91813.1 - 0.0087 15.8 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EAX91813.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Pex2_Pex12 PF04757.14 EAX91813.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.0 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF494 PF04361.13 EAX91813.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) FRQ PF09421.10 EAX91814.1 - 0.031 12.3 0.6 0.045 11.8 0.6 1.1 1 0 0 1 1 1 0 Frequency clock protein AAA PF00004.29 EAX91815.1 - 3.7e-20 72.7 0.0 6.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 EAX91815.1 - 6.5e-12 45.5 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Nucleoporin_FG PF13634.6 EAX91815.1 - 7.1e-06 26.8 123.2 0.41 11.5 10.3 8.9 1 1 5 6 6 4 2 Nucleoporin FG repeat region AAA_16 PF13191.6 EAX91815.1 - 0.00018 22.0 0.5 0.032 14.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EAX91815.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain CDC48_2 PF02933.17 EAX91815.1 - 0.0044 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.27 EAX91815.1 - 0.0056 17.2 0.0 0.019 15.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 EAX91815.1 - 0.0063 16.8 0.1 0.087 13.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EAX91815.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EAX91815.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 EAX91815.1 - 0.017 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAX91815.1 - 0.026 14.3 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAX91815.1 - 0.028 13.7 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EAX91815.1 - 0.029 14.4 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EAX91815.1 - 0.053 12.7 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EAX91815.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EAX91815.1 - 0.1 11.8 0.1 0.71 9.0 0.0 2.2 1 1 1 2 2 2 0 TIP49 P-loop domain RRM_Rrp7 PF17799.1 EAX91816.1 - 0.067 13.0 0.2 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain T5orf172 PF10544.9 EAX91817.1 - 5.2e-06 26.9 0.2 1.2e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX91818.1 - 4.3e-35 119.9 0.7 8.9e-35 118.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Autophagy_N PF03986.13 EAX91819.1 - 0.0061 16.5 0.1 1.1 9.2 0.0 2.2 1 1 1 2 2 2 2 Autophagocytosis associated protein (Atg3), N-terminal domain Pox_A32 PF04665.12 EAX91820.1 - 6.5e-07 29.1 4.4 6.5e-07 29.1 4.4 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX91820.1 - 7.3e-05 22.6 0.2 0.41 10.3 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX91820.1 - 0.0001 22.6 0.1 0.00085 19.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX91820.1 - 0.00012 22.1 2.9 0.0003 20.8 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91820.1 - 0.0008 19.2 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX91820.1 - 0.0013 18.4 0.6 0.01 15.5 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX91820.1 - 0.0015 18.4 0.5 0.0027 17.5 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX91820.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX91820.1 - 0.071 12.7 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX91820.1 - 0.094 13.1 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX91820.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX91820.1 - 0.32 11.2 3.9 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX91822.1 - 1.9e-57 193.2 9.4 2.1e-57 193.1 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX91822.1 - 0.11 12.8 0.1 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide ABC_tran PF00005.27 EAX91823.1 - 3.4e-06 27.6 0.9 6e-06 26.8 0.9 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX91823.1 - 1.1e-05 24.8 39.2 1.7e-05 24.1 38.6 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 EAX91823.1 - 0.8 10.2 7.2 0.083 13.4 1.8 2.0 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EAX91824.1 - 0.0044 16.9 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EAX91824.1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 EAX91825.1 - 4.6e-26 92.0 0.0 6.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX91825.1 - 1e-11 45.2 0.0 2.4e-05 24.3 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX91825.1 - 1.4e-06 27.9 0.2 0.0017 17.8 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAX91825.1 - 2.6e-06 27.1 0.2 4.7e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAX91825.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EAX91825.1 - 2.2e-05 25.1 0.1 4.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAX91825.1 - 0.0002 21.2 0.1 0.00038 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 EAX91825.1 - 0.0015 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EAX91825.1 - 0.0021 18.1 0.3 0.0044 17.1 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EAX91825.1 - 0.0033 17.2 0.0 0.0083 15.9 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 EAX91825.1 - 0.0059 16.4 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAX91825.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2813 PF11398.8 EAX91825.1 - 0.014 14.7 0.1 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Adeno_IVa2 PF02456.15 EAX91825.1 - 0.016 14.0 0.3 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 EAX91825.1 - 0.023 14.9 0.0 0.31 11.3 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EAX91825.1 - 0.023 14.3 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX91825.1 - 0.025 14.2 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EAX91825.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EAX91825.1 - 0.029 14.6 0.0 0.061 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX91825.1 - 0.032 13.9 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX91825.1 - 0.032 13.7 0.0 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 EAX91825.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EAX91825.1 - 0.045 12.9 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 EAX91825.1 - 0.05 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAX91825.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EAX91825.1 - 0.057 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAX91825.1 - 0.061 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 EAX91825.1 - 0.065 12.6 0.2 0.14 11.5 0.1 1.5 2 0 0 2 2 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EAX91825.1 - 0.075 13.4 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EAX91825.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FeoB_N PF02421.18 EAX91825.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 EAX91825.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EAX91825.1 - 0.13 12.2 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 EAX91825.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.21 EAX91825.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase DGOK PF05035.12 EAX91825.1 - 0.16 10.8 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 2-keto-3-deoxy-galactonokinase AAA_5 PF07728.14 EAX91825.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAX91825.1 - 0.18 11.2 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 EAX91825.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 EAX91826.1 - 8.3e-25 87.9 0.0 1.4e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX91826.1 - 5.4e-08 33.0 5.2 0.00076 19.4 0.0 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EAX91826.1 - 0.011 16.1 0.1 0.066 13.6 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EAX91826.1 - 0.016 15.8 1.5 0.022 15.3 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAX91826.1 - 0.057 13.8 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAX91826.1 - 0.071 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EAX91826.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EAX91826.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EAX91826.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PI3_PI4_kinase PF00454.27 EAX91827.1 - 2e-31 109.7 0.1 6.4e-22 78.6 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EAX91827.1 - 5.4e-26 91.1 1.8 1.1e-25 90.2 1.8 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EAX91827.1 - 1.3e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2573 PF10835.8 EAX91827.1 - 0.14 12.5 0.1 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) PSP PF04046.16 EAX91828.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX91829.1 - 0.012 15.6 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX91829.1 - 0.073 13.7 7.7 4.6 8.3 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX91830.1 - 0.03 14.8 0.9 0.077 13.5 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX91831.1 - 7.5e-87 285.3 60.2 4.3e-30 103.6 13.5 5.6 2 2 4 6 6 5 4 Phage tail repeat like DUF4116 PF13475.6 EAX91831.1 - 0.037 13.7 0.9 0.069 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Peptidase_S66 PF02016.15 EAX91831.1 - 0.068 13.3 0.6 67 3.6 0.1 3.8 1 1 2 3 3 3 0 LD-carboxypeptidase N-terminal domain AviRa PF11599.8 EAX91831.1 - 0.21 11.0 5.0 1 8.8 0.5 2.4 1 1 1 2 2 2 0 RRNA methyltransferase AviRa GPS2_interact PF15784.5 EAX91834.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91834.1 - 0.08 11.9 0.1 0.083 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX91835.1 - 0.093 12.7 11.1 0.15 12.1 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX91835.1 - 8.4 6.8 5.8 12 6.3 5.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Patched PF02460.18 EAX91839.1 - 0.11 10.6 0.0 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Patched family adh_short PF00106.25 EAX91840.1 - 2.8e-32 111.8 0.0 3.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAX91840.1 - 4.6e-21 75.5 0.0 5.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAX91840.1 - 2.7e-09 36.9 0.1 3.5e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAX91840.1 - 9.5e-08 32.2 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAX91840.1 - 8.1e-07 28.7 0.4 9.9e-07 28.4 0.4 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAX91840.1 - 7.4e-05 22.7 0.0 9.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EAX91840.1 - 0.01 16.4 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EAX91840.1 - 0.016 14.4 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 EAX91840.1 - 0.036 13.7 0.1 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EAX91840.1 - 0.071 12.7 0.1 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_4 PF13439.6 EAX91840.1 - 0.081 12.9 0.1 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Shikimate_DH PF01488.20 EAX91840.1 - 0.092 12.8 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1833 PF08875.11 EAX91840.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) NAD_binding_2 PF03446.15 EAX91840.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TM1586_NiRdase PF14512.6 EAX91841.1 - 1.2e-10 41.3 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 EAX91841.1 - 0.041 13.9 0.7 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Nitroreductase family DUF1816 PF08846.10 EAX91841.1 - 0.13 12.3 1.0 0.51 10.4 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1816) adh_short PF00106.25 EAX91842.1 - 1.3e-36 125.9 0.2 1.7e-35 122.3 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAX91842.1 - 2.6e-25 89.4 0.1 2e-24 86.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAX91842.1 - 8.1e-10 38.6 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAX91842.1 - 9.5e-10 38.7 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAX91842.1 - 1.2e-07 31.4 0.2 1.6e-07 31.1 0.2 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAX91842.1 - 5.3e-05 23.2 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EAX91842.1 - 0.018 15.6 0.1 0.035 14.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EAX91842.1 - 0.03 13.5 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 EAX91842.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EAX91842.1 - 0.099 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 EAX91842.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_4 PF13439.6 EAX91842.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 PSP PF04046.16 EAX91843.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX91844.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX91845.1 - 0.032 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Pox_A32 PF04665.12 EAX91846.1 - 5.8e-08 32.5 1.3 7.3e-08 32.2 1.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX91846.1 - 0.0041 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX91846.1 - 0.046 13.4 0.1 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX91846.1 - 0.071 13.1 0.4 0.63 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) adh_short PF00106.25 EAX91847.1 - 1e-34 119.7 0.0 1.1e-33 116.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAX91847.1 - 2e-22 79.9 0.0 9.1e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAX91847.1 - 1.1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAX91847.1 - 2.3e-05 24.4 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAX91847.1 - 0.00047 19.7 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAX91847.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding MatE PF01554.18 EAX91848.1 - 1.5e-07 31.2 0.4 1.5e-07 31.2 0.4 2.8 1 1 1 2 2 2 1 MatE Ninjurin PF04923.12 EAX91848.1 - 0.23 11.4 0.2 0.23 11.4 0.2 2.8 3 2 1 4 4 4 0 Ninjurin DHC_N2 PF08393.13 EAX91849.1 - 1.1e-35 123.5 8.2 1.1e-35 123.5 8.2 5.9 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 HU-CCDC81_bac_2 PF18175.1 EAX91849.1 - 0.015 15.1 3.5 0.046 13.6 0.5 3.4 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 BORCS8 PF10167.9 EAX91849.1 - 2.3 8.2 8.5 0.74 9.8 0.2 4.1 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 DASH_Dad1 PF08649.10 EAX91849.1 - 2.3 8.5 8.3 15 5.9 0.3 4.7 3 0 0 3 3 3 0 DASH complex subunit Dad1 PUNUT PF16913.5 EAX91850.1 - 0.00025 20.4 7.2 0.00025 20.4 7.2 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EAX91850.1 - 0.0065 16.6 6.0 0.0065 16.6 6.0 2.3 2 0 0 2 2 2 1 EamA-like transporter family Ank_2 PF12796.7 EAX91851.1 - 0.0061 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF4107 PF13389.6 EAX91852.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX91854.1 - 7.6e-07 28.8 2.4 7.6e-07 28.8 2.4 2.1 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX91854.1 - 3.5e-05 23.6 0.2 0.36 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX91854.1 - 4e-05 23.9 0.2 0.00029 21.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX91854.1 - 0.00049 20.1 4.8 0.00097 19.2 4.2 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX91854.1 - 0.00068 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX91854.1 - 0.0016 18.3 0.5 0.0035 17.2 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX91854.1 - 0.0062 16.2 2.1 0.015 15.0 0.2 2.3 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX91854.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX91854.1 - 0.089 12.3 0.0 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX91854.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX91854.1 - 0.15 12.5 0.7 0.96 9.9 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF573 PF04504.14 EAX91854.1 - 0.58 10.9 11.1 0.29 11.8 1.4 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX91854.1 - 0.74 10.1 4.9 9.7 6.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX91855.1 - 3.8e-43 145.9 0.8 7.2e-43 145.0 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX91855.1 - 0.0048 17.5 0.1 0.014 16.0 0.0 1.7 2 0 0 2 2 2 1 Parathyroid hormone family KilA-N PF04383.13 EAX91856.1 - 1.5e-09 37.7 3.8 2.3e-09 37.1 3.8 1.4 1 1 0 1 1 1 1 KilA-N domain Hormone_3 PF00159.18 EAX91856.1 - 4.2 7.5 5.2 25 5.1 0.2 2.5 3 0 0 3 3 3 0 Pancreatic hormone peptide DUF3839 PF12943.7 EAX91857.1 - 3.6e-155 514.5 10.8 4.6e-155 514.1 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX91857.1 - 0.11 12.4 0.8 0.44 10.4 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF1493 PF07377.12 EAX91858.1 - 0.065 13.7 1.2 0.1 13.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX91858.1 - 0.37 10.9 2.9 8.9 6.4 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TPR_MLP1_2 PF07926.12 EAX91859.1 - 0.011 15.8 0.3 0.012 15.6 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX91859.1 - 0.059 13.2 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Tho2 PF11262.8 EAX91859.1 - 0.098 11.8 2.5 0.11 11.7 2.5 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ADK PF00406.22 EAX91860.1 - 2.2e-38 131.7 0.1 4.6e-38 130.7 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAX91860.1 - 5.4e-25 88.4 0.0 1.1e-24 87.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAX91860.1 - 2.7e-11 44.1 0.0 5.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX91860.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EAX91860.1 - 0.021 15.0 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EAX91860.1 - 0.028 14.1 0.9 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EAX91860.1 - 0.029 14.1 0.1 0.057 13.1 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase PAS_7 PF12860.7 EAX91860.1 - 0.089 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 PAS fold NACHT PF05729.12 EAX91860.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EAX91860.1 - 0.12 12.7 0.1 0.97 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.26 EAX91861.1 - 1.6e-10 40.8 1.9 2.2e-10 40.3 1.9 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Myb_DNA-binding PF00249.31 EAX91862.1 - 1.3e-17 63.7 1.6 3.5e-08 33.5 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91862.1 - 1.7e-13 50.6 3.9 2.9e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX91862.1 - 4.3e-05 23.3 0.3 7.9e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX91862.1 - 6.8e-05 23.0 1.9 0.0072 16.5 0.5 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX91862.1 - 0.0038 17.6 1.6 0.35 11.3 0.1 2.6 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF563 PF04577.14 EAX91863.1 - 8.1e-30 104.5 0.2 1.1e-29 104.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) AMMECR1 PF01871.17 EAX91864.1 - 2.7e-46 157.2 0.0 3.1e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 zf-UBP_var PF17807.1 EAX91864.1 - 0.17 11.6 1.2 1.5 8.7 0.3 2.6 3 0 0 3 3 3 0 Variant UBP zinc finger DUF1493 PF07377.12 EAX91866.1 - 0.02 15.3 0.4 0.041 14.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX91867.1 - 1.2e-24 86.1 11.7 1.2e-24 86.1 11.7 4.6 5 1 1 6 6 5 1 Phage tail repeat like DUF3839 PF12943.7 EAX91868.1 - 2.5e-117 390.6 8.1 2.9e-117 390.4 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX91870.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91871.1 - 7e-72 240.9 2.3 9.1e-72 240.5 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Spectrin_like PF18373.1 EAX91872.1 - 0.0023 18.0 2.5 0.0041 17.1 2.0 1.7 1 1 0 1 1 1 1 Spectrin like domain Erp_C PF06780.11 EAX91872.1 - 0.02 14.9 6.7 0.03 14.3 6.7 1.2 1 0 0 1 1 1 0 Erp protein C-terminus UPF0223 PF05256.12 EAX91872.1 - 0.056 13.8 2.8 0.12 12.7 2.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) Terminase_3C PF17288.2 EAX91872.1 - 0.15 12.5 7.0 0.33 11.3 6.9 1.7 1 1 1 2 2 2 0 Terminase RNAseH like domain Oxidored_q3 PF00499.20 EAX91873.1 - 0.011 15.4 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TMEM154 PF15102.6 EAX91873.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF2463 PF09591.10 EAX91873.1 - 0.035 14.0 0.4 0.035 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) DUF3377 PF11857.8 EAX91873.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ATP_synth_reg PF14960.6 EAX91873.1 - 0.35 10.4 1.2 4 7.0 0.3 2.2 1 1 1 2 2 2 0 ATP synthase regulation Pkinase PF00069.25 EAX91875.1 - 1.7e-71 240.7 0.0 2.6e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91875.1 - 2.2e-44 151.7 0.0 3.2e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX91875.1 - 5.6e-05 22.3 0.0 9.8e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX91875.1 - 0.00019 21.5 0.5 0.0019 18.1 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX91875.1 - 0.00041 19.8 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAX91875.1 - 0.0046 16.6 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EAX91875.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chromo_shadow PF01393.19 EAX91876.1 - 0.00014 21.9 0.1 0.00041 20.4 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EAX91876.1 - 0.0015 18.4 0.4 0.003 17.4 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank_2 PF12796.7 EAX91878.1 - 3.6e-184 597.9 98.9 2.2e-19 69.8 1.6 15.9 4 2 15 19 19 19 19 Ankyrin repeats (3 copies) Ank PF00023.30 EAX91878.1 - 3.4e-172 552.2 60.7 5.6e-08 32.9 0.1 25.1 25 0 0 25 25 25 23 Ankyrin repeat Ank_4 PF13637.6 EAX91878.1 - 2.1e-133 433.1 35.7 4.6e-11 43.0 0.0 24.3 4 2 21 25 25 25 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91878.1 - 8.4e-129 403.7 30.5 3.9e-06 26.8 0.0 25.9 26 0 0 26 26 26 22 Ankyrin repeat Ank_5 PF13857.6 EAX91878.1 - 1.5e-83 273.7 35.3 1.3e-10 41.3 0.1 16.1 5 4 16 21 21 21 20 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91878.1 - 2.5e-37 126.7 11.2 2.9e-37 126.5 6.4 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) FIVAR PF07554.13 EAX91878.1 - 3.3 8.5 7.7 0.19 12.5 0.8 2.3 2 0 0 2 2 2 0 FIVAR domain PSP PF04046.16 EAX91879.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX91880.1 - 0.039 14.4 0.8 0.11 12.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4108 PF13390.6 EAX91882.1 - 3.7e-62 208.5 6.0 4.1e-62 208.3 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX91883.1 - 3.3e-05 24.3 3.0 0.00017 22.0 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX91883.1 - 0.017 15.7 0.1 0.033 14.8 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX91883.1 - 0.061 13.3 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PSP PF04046.16 EAX91885.1 - 0.073 13.0 0.6 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Adaptin_N PF01602.20 EAX91886.1 - 5e-64 216.7 8.5 7.2e-64 216.2 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX91886.1 - 8.7e-06 25.9 5.2 0.014 15.4 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 EAX91886.1 - 1.6e-05 25.2 4.6 0.064 13.6 0.0 2.8 2 0 0 2 2 2 2 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 EAX91886.1 - 0.068 13.6 0.0 5.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2730 PF10805.8 EAX91887.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) NLE PF08154.12 EAX91887.1 - 0.12 12.9 0.5 0.25 11.9 0.3 1.6 1 1 0 1 1 1 0 NLE (NUC135) domain Ank_2 PF12796.7 EAX91888.1 - 5.5e-18 65.3 0.2 2.4e-14 53.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91888.1 - 1.4e-15 57.5 0.1 3e-08 34.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX91888.1 - 1.6e-15 56.7 0.9 1.1e-05 25.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX91888.1 - 6.7e-12 45.4 0.2 1.2e-09 38.2 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX91888.1 - 1.8e-07 30.9 0.3 0.018 15.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat LPP PF04728.13 EAX91889.1 - 0.059 13.8 23.7 4.4 7.8 0.0 7.3 6 1 0 6 6 6 0 Lipoprotein leucine-zipper DAOA PF15199.6 EAX91889.1 - 0.064 13.7 0.3 1.8 9.1 0.0 3.0 2 1 1 3 3 3 0 D-amino acid oxidase activator ABC_tran_CTD PF16326.5 EAX91889.1 - 0.79 10.0 25.2 0.051 13.8 1.9 6.7 5 1 1 6 6 6 0 ABC transporter C-terminal domain TSC22 PF01166.18 EAX91889.1 - 1.5 9.2 9.0 9.9 6.6 0.1 5.2 4 0 0 4 4 4 0 TSC-22/dip/bun family DUF4806 PF16064.5 EAX91889.1 - 3.6 8.0 7.1 1.8 8.9 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4806) DASH_Dam1 PF08653.10 EAX91889.1 - 5.3 6.9 18.5 5.9 6.8 0.8 6.1 7 0 0 7 7 7 0 DASH complex subunit Dam1 Occludin_ELL PF07303.13 EAX91889.1 - 7 7.4 26.1 3.3 8.5 0.9 5.7 5 2 0 5 5 5 0 Occludin homology domain Proteasome PF00227.26 EAX91890.1 - 4.7e-58 195.8 0.4 5.8e-58 195.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAX91890.1 - 3e-10 39.6 0.2 6.9e-10 38.4 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GPS2_interact PF15784.5 EAX91892.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91892.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX91893.1 - 0.074 13.0 10.5 0.12 12.4 10.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.13 EAX91894.1 - 1.8e-30 106.2 5.8 2.6e-30 105.7 5.8 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PTR PF12789.7 EAX91896.1 - 3e-133 434.0 94.5 2.9e-32 110.5 14.7 5.9 3 2 5 8 8 7 5 Phage tail repeat like DUF4795 PF16043.5 EAX91896.1 - 0.16 11.5 16.6 1.6e+02 1.8 16.6 3.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF2785 PF10978.8 EAX91896.1 - 0.16 11.7 6.3 0.45 10.3 4.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2785) Apolipoprotein PF01442.18 EAX91896.1 - 0.97 9.3 4.7 4.5 7.1 4.7 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1493 PF07377.12 EAX91897.1 - 0.086 13.3 0.5 0.18 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX91898.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX91899.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX91900.1 - 4.3e-43 145.8 1.0 2.9e-14 53.4 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX91900.1 - 8.4e-39 127.2 1.5 0.0002 21.5 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX91900.1 - 1.4e-38 130.4 10.7 4.8e-08 33.1 0.1 6.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX91900.1 - 4.5e-37 126.0 2.5 6.3e-08 33.0 0.2 6.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX91900.1 - 1.9e-31 107.1 2.3 0.00022 21.5 0.5 6.6 6 0 0 6 6 6 6 Ankyrin repeat MIT_C PF16565.5 EAX91900.1 - 0.00012 22.1 0.4 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase D-like domain at C-terminus of MIT PgdA_N PF18627.1 EAX91900.1 - 0.083 12.5 0.5 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Peptidoglycan GlcNAc deacetylase N-terminal domain Pkinase PF00069.25 EAX91901.1 - 2.8e-37 128.5 0.0 4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91901.1 - 1.6e-21 76.8 0.0 2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX91901.1 - 2.8e-06 26.8 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX91901.1 - 0.00069 18.8 0.1 0.0014 17.8 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAX91901.1 - 0.02 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.6 EAX91902.1 - 3.6e-07 29.9 8.1 3.6e-07 29.9 8.1 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 EAX91902.1 - 0.047 14.5 0.7 0.047 14.5 0.7 7.9 7 4 1 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX91902.1 - 0.06 13.8 0.4 0.06 13.8 0.4 6.5 7 1 0 7 7 7 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 EAX91902.1 - 0.63 10.4 18.7 0.094 13.0 4.3 3.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EAX91902.1 - 1.6 9.1 20.7 1.4 9.3 4.9 4.1 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Ank_2 PF12796.7 EAX91903.1 - 8.3e-79 260.2 54.7 4.9e-17 62.3 3.2 6.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX91903.1 - 6.1e-74 243.5 17.4 7.6e-14 51.9 0.1 11.1 4 3 8 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX91903.1 - 1.3e-67 221.5 22.4 2.5e-08 34.0 0.0 10.6 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 EAX91903.1 - 1.4e-57 184.9 20.8 8.4e-06 25.8 0.0 11.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAX91903.1 - 2.8e-49 164.5 15.6 1.4e-10 41.2 0.1 8.7 7 1 2 9 9 9 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX91903.1 - 3.9e-38 129.3 8.7 3.9e-38 129.3 8.7 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) HCNGP PF07818.13 EAX91903.1 - 0.0031 18.1 1.9 5.8 7.6 0.1 3.3 3 0 0 3 3 3 2 HCNGP-like protein Shigella_OspC PF06128.11 EAX91903.1 - 0.0066 16.2 14.6 3.3 7.4 0.1 4.3 2 2 3 5 5 5 3 Shigella flexneri OspC protein DAGK_cat PF00781.24 EAX91904.1 - 4.2e-09 36.1 0.0 4.8e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Minor_capsid_3 PF12691.7 EAX91904.1 - 0.086 13.2 0.0 0.093 13.1 0.0 1.0 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage DUF4652 PF15525.6 EAX91904.1 - 0.089 12.6 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) DAGK_acc PF00609.19 EAX91905.1 - 1.4e-39 136.0 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EAX91905.1 - 1.9e-05 24.3 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 EAX91907.1 - 3.3e-68 229.9 0.0 3.7e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91907.1 - 1.7e-41 142.2 0.0 2e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX91907.1 - 5.1e-10 38.8 0.1 7e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAX91907.1 - 0.0002 21.0 0.4 0.00032 20.3 0.3 1.4 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAX91907.1 - 0.00023 20.6 0.0 0.0033 16.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EAX91907.1 - 0.00056 19.9 0.1 0.001 19.1 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX91907.1 - 0.00086 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAX91907.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase ABC1 PF03109.16 EAX91907.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC1 family YrbL-PhoP_reg PF10707.9 EAX91907.1 - 0.029 13.9 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EAX91907.1 - 0.093 12.7 0.4 0.48 10.4 0.1 2.1 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins PSP PF04046.16 EAX91908.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX91910.1 - 0.023 15.2 0.5 0.048 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX91911.1 - 2.6e-11 43.4 13.1 2e-08 34.2 0.3 5.2 5 0 0 5 5 5 2 Phage tail repeat like DUF2120 PF09893.9 EAX91911.1 - 0.79 9.8 3.0 11 6.1 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) EMP24_GP25L PF01105.24 EAX91911.1 - 1.1 9.2 5.0 6.8 6.6 0.0 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4795 PF16043.5 EAX91911.1 - 1.5 8.3 10.0 0.83 9.2 6.3 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX91912.1 - 6.9e-141 467.7 7.9 1.1e-140 467.1 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX91912.1 - 0.073 13.5 0.4 0.99 9.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX91912.1 - 0.75 10.3 4.8 4.3 7.9 0.5 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX91913.1 - 0.00032 21.2 0.1 0.00079 19.9 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX91913.1 - 0.0047 16.7 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain Prenyltrans PF00432.21 EAX91914.1 - 5e-50 166.9 8.0 2.6e-12 46.2 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EAX91914.1 - 7.9e-08 31.8 0.0 2.3e-05 23.7 0.0 2.9 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EAX91914.1 - 1.4e-06 27.6 0.0 0.0099 15.0 0.0 3.1 1 1 2 3 3 3 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EAX91914.1 - 1.3e-05 24.4 0.1 0.16 10.9 0.0 3.0 1 1 1 3 3 3 2 A-macroglobulin TED domain Pkinase PF00069.25 EAX91915.1 - 9.2e-61 205.5 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX91915.1 - 1.2e-41 142.8 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EAX91915.1 - 2.5e-10 40.5 0.3 2.8e-08 34.0 0.1 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EAX91915.1 - 0.00012 21.0 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 EAX91916.1 - 1.3e-21 76.5 1.3 4e-05 24.3 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX91916.1 - 8.8e-12 45.2 0.3 0.0046 17.2 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAX91916.1 - 2.4e-07 30.6 0.1 9.2e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.14 EAX91916.1 - 8e-07 28.5 1.1 4.1e-06 26.1 0.7 1.9 1 1 1 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 EAX91916.1 - 1e-06 27.9 0.9 0.76 8.7 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAX91916.1 - 0.00024 19.9 5.9 0.68 8.5 0.0 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EAX91916.1 - 0.00027 21.3 0.0 0.2 12.2 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain VID27 PF08553.10 EAX91916.1 - 0.001 18.2 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain MMS1_N PF10433.9 EAX91916.1 - 0.0023 16.6 0.1 0.0048 15.6 0.1 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Frtz PF11768.8 EAX91916.1 - 0.0034 15.8 0.0 0.22 9.8 0.0 2.2 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 EAX91916.1 - 0.025 13.1 0.2 0.063 11.8 0.2 1.6 1 1 0 1 1 1 0 Utp8 family Nucleoporin_N PF08801.11 EAX91916.1 - 0.033 13.0 1.1 1.4 7.6 1.1 3.3 1 1 0 1 1 1 0 Nup133 N terminal like AlphaC_N PF08829.10 EAX91916.1 - 0.038 14.0 0.2 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Alpha C protein N terminal Cytochrom_D1 PF02239.16 EAX91916.1 - 0.045 12.3 0.0 1.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ago_hook PF10427.9 EAX91916.1 - 0.091 13.3 1.6 0.46 11.0 0.6 2.1 2 0 0 2 2 2 0 Argonaute hook DUF1513 PF07433.11 EAX91916.1 - 0.15 11.1 0.1 2.9 6.9 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Clat_adaptor_s PF01217.20 EAX91918.1 - 3.5e-45 153.4 0.7 4e-45 153.3 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4107 PF13389.6 EAX91919.1 - 7.9e-72 240.7 3.6 1e-71 240.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX91921.1 - 3.9e-96 321.2 6.8 4.4e-96 321.0 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX91921.1 - 0.033 13.7 0.3 0.038 13.5 0.3 1.1 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX91921.1 - 0.13 12.9 1.1 0.42 11.3 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAX91922.1 - 1.9e-28 99.5 7.4 2.8e-28 99.0 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX91922.1 - 0.042 14.1 0.5 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 PRD domain Val_tRNA-synt_C PF10458.9 EAX91922.1 - 0.063 13.6 0.8 0.13 12.5 0.8 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm KilA-N PF04383.13 EAX91923.1 - 7.2e-40 135.3 1.0 1.5e-39 134.3 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX91924.1 - 3.3e-37 128.5 14.4 1.4e-36 126.4 14.4 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX91925.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Trypan_PARP PF05887.11 EAX91926.1 - 0.15 12.1 11.5 0.2 11.6 11.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX91927.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX91927.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Myb_DNA-binding PF00249.31 EAX91929.1 - 4.9e-28 97.1 0.7 1.6e-16 60.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91929.1 - 1.8e-21 76.1 0.0 4.5e-11 42.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91929.1 - 0.00027 20.9 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 SLIDE TFIIA PF03153.13 EAX91929.1 - 0.13 12.2 6.4 0.17 11.9 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3839 PF12943.7 EAX91930.1 - 3.2e-155 514.6 14.8 3.9e-155 514.4 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX91930.1 - 0.06 13.8 1.7 0.17 12.3 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX91930.1 - 0.51 10.8 7.1 1.9 9.0 0.4 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX91930.1 - 2.2 8.6 5.7 5.1 7.4 0.2 3.4 2 2 1 3 3 3 0 Rx N-terminal domain PSP PF04046.16 EAX91932.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Amidase02_C PF12123.8 EAX91933.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX91934.1 - 5.8e-72 241.1 3.3 8.8e-72 240.6 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) COMM_domain PF07258.14 EAX91935.1 - 7.1e-09 35.7 0.0 2.8e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 COMM domain GATase_6 PF13522.6 EAX91935.1 - 0.095 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Tub PF01167.18 EAX91936.1 - 0.00084 19.2 4.4 0.0034 17.2 0.1 2.6 3 0 0 3 3 3 2 Tub family DUF3527 PF12043.8 EAX91936.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3527) VPS9 PF02204.18 EAX91937.1 - 0.00037 20.7 4.5 0.00044 20.4 0.2 3.2 3 2 1 4 4 4 1 Vacuolar sorting protein 9 (VPS9) domain TIM PF00121.18 EAX91938.1 - 8.4e-85 284.0 0.0 9.5e-85 283.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF5016 PF16408.5 EAX91938.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5016) AP_endonuc_2 PF01261.24 EAX91938.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel tRNA_int_endo PF01974.17 EAX91939.1 - 6e-14 51.9 0.1 1e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Nckap1 PF09735.9 EAX91941.1 - 1.5e-16 59.7 13.1 4.9e-12 44.7 0.0 3.3 3 0 0 3 3 3 3 Membrane-associated apoptosis protein SSPI PF14098.6 EAX91941.1 - 0.097 12.8 0.1 0.96 9.7 0.0 2.6 2 0 0 2 2 2 0 Small, acid-soluble spore protein I IF-2B PF01008.17 EAX91941.1 - 0.14 11.4 0.5 0.25 10.5 0.5 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family Gly_rich PF12810.7 EAX91943.1 - 1.1e-24 87.7 42.2 1.3e-24 87.5 42.2 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF4108 PF13390.6 EAX91944.1 - 5.8e-64 214.3 6.4 6.4e-64 214.2 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX91946.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX91946.1 - 0.0026 18.0 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX91946.1 - 0.0036 17.7 0.0 0.0053 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX91946.1 - 0.0044 17.0 0.0 0.0058 16.7 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX91946.1 - 0.02 14.4 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX91946.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAX91946.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EAX91946.1 - 0.095 12.4 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX91946.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4106 PF13388.6 EAX91947.1 - 1.1e-237 789.1 17.9 1.1e-237 789.1 17.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX91947.1 - 0.033 14.0 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) AviRa PF11599.8 EAX91947.1 - 0.16 11.4 2.8 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 RRNA methyltransferase AviRa FapA PF03961.13 EAX91947.1 - 0.91 8.1 9.7 0.3 9.6 4.9 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF3452 PF11934.8 EAX91947.1 - 1.2 8.7 3.4 1.1 8.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4446 PF14584.6 EAX91947.1 - 9.9 6.1 8.0 0.89 9.5 1.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Myb_DNA-binding PF00249.31 EAX91948.1 - 1.5e-25 89.1 4.2 1.3e-12 47.7 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91948.1 - 4.7e-16 58.8 1.7 3.8e-10 39.9 0.2 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91948.1 - 1.6e-07 31.3 0.2 0.0029 17.6 0.1 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-binding PF00249.31 EAX91949.1 - 1.5e-28 98.7 2.2 3.5e-16 59.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91949.1 - 1.5e-22 79.6 1.3 3.4e-11 43.2 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91949.1 - 8e-11 42.0 0.1 5.2e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91949.1 - 0.016 15.1 3.8 2.2 8.2 0.1 2.7 3 0 0 3 3 3 0 Myb DNA-binding like HTH_AsnC-type PF13404.6 EAX91949.1 - 0.042 13.7 0.0 0.42 10.5 0.0 2.6 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 EAX91949.1 - 0.17 12.3 4.0 3.9 7.9 0.6 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain TMP PF05017.14 EAX91950.1 - 0.15 12.7 8.0 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX91950.1 - 6 6.9 8.5 6.6 6.7 8.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1493 PF07377.12 EAX91951.1 - 0.055 13.9 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX91953.1 - 6.5e-143 474.3 10.4 8.1e-143 474.0 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX91953.1 - 0.36 11.3 2.4 2.1 8.9 0.8 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Myb_DNA-binding PF00249.31 EAX91954.1 - 3.7e-26 91.0 2.9 1.5e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91954.1 - 4.7e-18 65.2 1.2 1.7e-10 41.0 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91954.1 - 3.5e-08 33.5 0.8 0.0025 17.8 0.1 2.4 2 0 0 2 2 2 2 SLIDE CBM65_1 PF18259.1 EAX91954.1 - 0.048 13.8 1.4 0.12 12.5 0.3 2.2 2 0 0 2 2 2 0 Carbohydrate binding module 65 domain 1 zf-A20 PF01754.16 EAX91954.1 - 0.053 13.5 0.2 0.097 12.6 0.2 1.4 1 0 0 1 1 1 0 A20-like zinc finger Myb_DNA-bind_7 PF15963.5 EAX91954.1 - 0.26 11.2 2.4 5.8 6.9 0.4 2.6 1 1 1 2 2 2 0 Myb DNA-binding like CHDCT2 PF08074.11 EAX91954.1 - 0.32 11.1 4.1 13 5.9 0.0 2.8 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 EAX91955.1 - 1.5e-24 85.9 1.1 4.8e-11 42.7 0.2 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX91955.1 - 1.5e-16 60.4 0.3 3e-09 37.0 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX91955.1 - 5.3e-06 26.4 0.1 0.077 13.0 0.0 2.7 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX91955.1 - 0.15 11.9 0.8 0.27 11.2 0.2 1.8 2 0 0 2 2 2 0 Myb DNA-binding like ABC_trans_aux PF03886.13 EAX91955.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component DUF4107 PF13389.6 EAX91956.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX91957.1 - 0.0097 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase TRAM_LAG1_CLN8 PF03798.16 EAX91958.1 - 7e-26 91.2 27.2 7e-26 91.2 27.2 1.4 2 0 0 2 2 2 1 TLC domain DUF1691 PF07950.11 EAX91958.1 - 0.062 14.0 0.0 0.17 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Ras PF00071.22 EAX91959.1 - 2e-46 157.5 0.6 2.3e-46 157.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91959.1 - 7.3e-31 106.9 0.1 1.1e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91959.1 - 7e-16 58.2 0.1 8.2e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX91959.1 - 9.2e-10 38.6 0.0 1.4e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX91959.1 - 1.7e-07 30.8 0.1 2.1e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX91959.1 - 7.6e-07 28.9 0.1 5.5e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX91959.1 - 7e-06 26.0 1.8 0.03 14.2 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EAX91959.1 - 8.6e-06 25.4 0.2 1.5e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EAX91959.1 - 1.3e-05 24.8 0.0 2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX91959.1 - 0.004 16.9 0.6 0.057 13.2 0.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EAX91959.1 - 0.0054 16.6 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EAX91959.1 - 0.014 15.4 0.3 0.03 14.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain DctA-YdbH PF11739.8 EAX91959.1 - 0.051 13.3 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 Dicarboxylate transport Abhydrolase_1 PF00561.20 EAX91960.1 - 1.9e-21 76.8 0.2 3.1e-18 66.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX91960.1 - 2.6e-14 53.1 0.0 7.6e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX91960.1 - 5.9e-09 36.8 0.0 7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EAX91960.1 - 8.1e-06 24.7 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EAX91960.1 - 0.00099 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EAX91960.1 - 0.0012 18.6 1.1 0.013 15.2 0.3 2.1 1 1 1 2 2 2 1 PGAP1-like protein DUF1057 PF06342.12 EAX91960.1 - 0.0013 17.9 0.1 0.0021 17.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ser_hydrolase PF06821.13 EAX91960.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 EAX91960.1 - 0.03 14.1 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF995 PF06191.12 EAX91960.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Abhydrolase_1 PF00561.20 EAX91961.1 - 2.4e-05 24.1 0.0 2.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF995 PF06191.12 EAX91961.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Hydrolase_4 PF12146.8 EAX91962.1 - 0.0079 15.5 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX91962.1 - 0.084 12.5 0.0 0.25 10.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1187 PF06688.11 EAX91962.1 - 0.25 11.7 1.1 0.85 10.0 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) TMF_TATA_bd PF12325.8 EAX91963.1 - 0.00038 20.7 17.2 0.00038 20.7 17.2 47.3 4 3 40 48 48 48 7 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EAX91963.1 - 0.00044 20.5 45.2 0.00044 20.5 45.2 35.8 2 2 30 33 33 33 7 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EAX91963.1 - 0.00091 19.1 28.0 0.00091 19.1 28.0 31.9 3 3 29 33 33 33 9 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EAX91963.1 - 0.0016 18.5 25.6 0.0016 18.5 25.6 39.3 2 2 38 42 42 42 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EAX91963.1 - 0.0026 17.8 9.8 0.0026 17.8 9.8 43.0 8 7 29 44 44 44 5 Protein of unknown function (DUF1664) LRR_6 PF13516.6 EAX91963.1 - 0.19 11.9 4.4 18 5.7 0.1 4.3 3 0 0 3 3 3 0 Leucine Rich repeat ILEI PF15711.5 EAX91965.1 - 0.062 13.8 0.7 0.39 11.2 0.2 2.4 1 1 1 2 2 2 0 Interleukin-like EMT inducer Aa_trans PF01490.18 EAX91966.1 - 1.6e-31 109.5 41.3 2e-31 109.1 41.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ECSCR PF15820.5 EAX91966.1 - 0.11 12.3 0.2 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator OST3_OST6 PF04756.13 EAX91968.1 - 2.1e-07 30.6 1.1 2.7e-07 30.3 1.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PIRT PF15099.6 EAX91968.1 - 0.076 12.6 0.7 0.11 12.1 0.7 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family OAD_gamma PF04277.13 EAX91968.1 - 0.65 10.6 0.1 0.65 10.6 0.1 2.4 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2627 PF11118.8 EAX91968.1 - 0.86 10.2 4.3 1.8 9.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Insulin_TMD PF17870.1 EAX91968.1 - 4.4 7.4 7.9 0.91 9.6 2.3 2.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment AbiJ_NTD4 PF18863.1 EAX91970.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX91970.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein Pox_A32 PF04665.12 EAX91971.1 - 1.7e-08 34.2 1.3 3.9e-08 33.1 0.2 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX91971.1 - 1.7e-07 31.1 0.3 8.8e-07 28.8 0.3 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX91971.1 - 0.036 13.9 2.4 0.06 13.2 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4107 PF13389.6 EAX91972.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Arm-DNA-bind_5 PF17293.2 EAX91973.1 - 4 7.9 14.2 1.2 9.6 7.4 3.2 2 2 0 2 2 2 0 Arm DNA-binding domain DUF3839 PF12943.7 EAX91975.1 - 4.8e-155 514.1 14.3 6.1e-155 513.7 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX91975.1 - 0.022 15.3 6.4 0.28 11.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX91975.1 - 0.079 13.4 2.9 0.16 12.4 0.5 2.1 2 0 0 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 EAX91975.1 - 0.25 11.3 5.0 1.7 8.7 0.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 EAX91975.1 - 0.42 11.1 9.5 1.2 9.7 2.0 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX91975.1 - 0.59 10.5 3.3 1 9.7 0.6 2.5 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit ZapB PF06005.12 EAX91975.1 - 3.3 8.2 5.3 2.4 8.6 0.1 3.0 4 0 0 4 4 4 0 Cell division protein ZapB Phage_fiber PF03335.13 EAX91976.1 - 5.8 7.4 8.1 18 5.9 1.8 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF2062 PF09835.9 EAX91979.1 - 0.68 9.8 5.9 0.16 11.8 1.1 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) BACK PF07707.15 EAX91980.1 - 2.8e-07 30.6 1.1 0.00012 22.1 0.5 2.5 2 0 0 2 2 2 2 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 EAX91980.1 - 0.0072 16.4 0.8 0.018 15.2 0.8 1.6 1 0 0 1 1 1 1 F5/8 type C domain SLX9 PF15341.6 EAX91980.1 - 0.28 11.6 4.4 13 6.2 0.0 3.5 3 1 0 3 3 3 0 Ribosome biogenesis protein SLX9 HMG_box PF00505.19 EAX91981.1 - 3.5e-14 53.0 0.4 4.9e-14 52.5 0.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX91981.1 - 4.9e-10 39.9 0.1 7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain Mem_trans PF03547.18 EAX91982.1 - 2.4e-06 26.2 0.8 2.6e-06 26.1 0.8 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF4349 PF14257.6 EAX91983.1 - 0.1 12.0 2.3 5.9 6.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TRPM_tetra PF16519.5 EAX91984.1 - 0.21 11.7 3.6 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Tetramerisation domain of TRPM BLOC1_2 PF10046.9 EAX91984.1 - 0.27 11.6 3.3 0.14 12.5 1.3 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EAX91984.1 - 0.66 10.5 6.8 1.2 9.7 6.0 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 EAX91984.1 - 3.3 7.7 10.0 4.7 7.3 1.5 2.7 1 1 2 3 3 3 0 FlxA-like protein CAF1 PF04857.20 EAX91985.1 - 2e-19 70.0 0.7 3.2e-09 36.4 0.0 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease RNase_T PF00929.24 EAX91985.1 - 0.056 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Exonuclease DUF4107 PF13389.6 EAX91986.1 - 2.6e-72 242.3 3.2 3.6e-72 241.8 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX91987.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase RRM_1 PF00076.22 EAX91989.1 - 8.3e-11 41.6 0.0 9.8e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX91989.1 - 3.9e-09 36.2 0.0 6.1e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX91989.1 - 0.072 13.0 0.0 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ras PF00071.22 EAX91990.1 - 1.4e-50 171.1 0.4 1.6e-50 170.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX91990.1 - 1.1e-31 109.6 0.2 1.7e-31 108.9 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX91990.1 - 3.2e-14 52.8 0.0 4e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX91990.1 - 5.4e-10 39.0 0.1 6.9e-10 38.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX91990.1 - 4.2e-06 26.8 0.1 7.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX91990.1 - 3.5e-05 23.6 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX91990.1 - 0.00058 19.4 0.4 0.0013 18.3 0.1 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 EAX91990.1 - 0.00069 19.0 0.1 0.0014 18.0 0.1 1.5 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 EAX91990.1 - 0.00093 19.1 0.1 0.067 13.1 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA PF00004.29 EAX91990.1 - 0.0025 18.3 0.0 0.0054 17.2 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX91990.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EAX91990.1 - 0.0056 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EAX91990.1 - 0.0066 16.2 0.1 0.0087 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EAX91990.1 - 0.0086 15.9 1.5 0.58 9.9 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EAX91990.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EAX91990.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAX91990.1 - 0.019 15.3 0.1 0.03 14.7 0.1 1.6 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EAX91990.1 - 0.023 15.2 0.1 0.028 14.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EAX91990.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EAX91990.1 - 0.18 11.7 0.0 0.6 10.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain E1-E2_ATPase PF00122.20 EAX91991.1 - 1.6e-40 138.5 0.0 6.3e-40 136.6 0.0 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAX91991.1 - 1e-36 126.4 6.7 1e-36 126.4 6.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAX91991.1 - 1.2e-23 84.6 0.1 2e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAX91991.1 - 2.9e-14 52.9 0.2 1.2e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EAX91991.1 - 1e-13 50.7 0.3 3.4e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAX91991.1 - 0.0013 18.6 4.4 0.032 14.0 0.1 3.0 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAX91991.1 - 0.0017 18.8 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2407_C PF13373.6 EAX91993.1 - 1.9e-07 31.3 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EAX91993.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Orn_DAP_Arg_deC PF00278.22 EAX91994.1 - 2.9e-24 85.1 0.0 3.2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 EAX91994.1 - 1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain FPL PF09758.9 EAX91995.1 - 2.9e-14 53.3 4.6 2.9e-14 53.3 4.6 2.8 3 1 0 3 3 3 1 Uncharacterised conserved protein DUF2153 PF09921.9 EAX91995.1 - 0.018 14.9 0.1 0.064 13.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Dynein_C PF18199.1 EAX91996.1 - 0.16 11.1 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Ribosomal_L27e PF01777.18 EAX91997.1 - 0.4 11.1 2.3 0.94 9.9 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family HSBP1 PF06825.12 EAX91998.1 - 0.0044 16.8 4.9 0.046 13.6 0.2 2.3 2 0 0 2 2 2 2 Heat shock factor binding protein 1 LXG PF04740.12 EAX91998.1 - 0.025 14.3 2.2 0.036 13.8 2.2 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily KNOX2 PF03791.13 EAX91998.1 - 0.07 12.6 0.2 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 KNOX2 domain TRPM_tetra PF16519.5 EAX91998.1 - 0.076 13.1 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM DUF620 PF04788.12 EAX91998.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF620) ArsA_ATPase PF02374.15 EAX91999.1 - 2.5e-80 269.9 2.1 2.2e-52 178.1 0.6 2.1 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 EAX91999.1 - 3.3e-12 46.7 0.5 1.9e-10 40.9 0.5 2.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EAX91999.1 - 2.1e-10 40.7 3.4 7.9e-10 38.9 3.4 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EAX91999.1 - 6.9e-08 32.2 0.7 4.6e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EAX91999.1 - 1.3e-06 28.0 0.7 1.6e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EAX91999.1 - 2.2e-05 24.2 0.2 0.0018 18.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EAX91999.1 - 0.00017 21.1 0.0 0.00036 20.1 0.0 1.5 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 EAX91999.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_24 PF13479.6 EAX91999.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EAX91999.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX91999.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.11 EAX91999.1 - 0.22 10.8 0.6 1.5 8.1 0.1 2.4 3 0 0 3 3 3 0 VirC1 protein AAA_25 PF13481.6 EAX91999.1 - 0.24 11.0 0.4 0.38 10.3 0.4 1.5 1 1 0 1 1 1 0 AAA domain C2 PF00168.30 EAX92000.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain DUF3377 PF11857.8 EAX92001.1 - 0.0018 18.1 0.6 0.0027 17.6 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF3671 PF12420.8 EAX92001.1 - 0.0021 18.1 0.8 0.003 17.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF2207 PF09972.9 EAX92001.1 - 0.0024 16.7 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EAX92001.1 - 0.0039 17.1 0.1 0.0057 16.6 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAX92001.1 - 0.0076 15.7 0.4 0.01 15.3 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RIFIN PF02009.16 EAX92001.1 - 0.016 15.2 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Rifin Stevor PF17410.2 EAX92001.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRRC37AB_C PF14914.6 EAX92001.1 - 0.016 15.1 0.4 0.021 14.7 0.4 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain ODV-E18 PF10717.9 EAX92001.1 - 0.017 15.0 0.4 0.025 14.4 0.4 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 EAX92001.1 - 0.02 14.7 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4448 PF14610.6 EAX92001.1 - 0.022 14.6 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Shisa PF13908.6 EAX92001.1 - 0.022 15.0 0.1 0.029 14.6 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5383 PF17355.2 EAX92001.1 - 0.024 15.0 1.5 0.037 14.4 1.5 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Orf78 PF06024.12 EAX92001.1 - 0.026 14.8 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) AJAP1_PANP_C PF15298.6 EAX92001.1 - 0.026 14.7 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Amnionless PF14828.6 EAX92001.1 - 0.043 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless AMA-1 PF02430.15 EAX92001.1 - 0.051 12.5 0.4 0.067 12.1 0.4 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Baculo_11_kDa PF06143.11 EAX92001.1 - 0.059 13.0 2.9 0.11 12.1 2.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Podoplanin PF05808.11 EAX92001.1 - 0.068 13.3 0.3 0.086 12.9 0.3 1.1 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 EAX92001.1 - 0.069 14.0 1.0 0.069 14.0 1.0 1.9 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SKN1 PF03935.15 EAX92001.1 - 0.13 10.6 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) DUF4690 PF15756.5 EAX92001.1 - 0.14 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF3844 PF12955.7 EAX92001.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) m04gp34like PF12216.8 EAX92001.1 - 0.19 11.2 0.1 0.25 10.9 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF929 PF06053.11 EAX92001.1 - 0.53 9.5 3.1 0.77 9.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SP_C-Propep PF08999.10 EAX92001.1 - 0.56 10.0 4.5 0.86 9.4 4.5 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide HemY_N PF07219.13 EAX92001.1 - 1.1 9.5 2.6 1.6 9.0 2.6 1.2 1 0 0 1 1 1 0 HemY protein N-terminus ECSCR PF15820.5 EAX92001.1 - 1.1 9.1 8.9 0.57 10.0 6.7 1.7 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator Vpu PF00558.19 EAX92001.1 - 3.2 7.6 6.0 8.5 6.2 2.9 2.3 2 0 0 2 2 2 0 Vpu protein FeoB_associated PF12669.7 EAX92001.1 - 6.5 7.2 5.6 13 6.3 5.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein C2 PF00168.30 EAX92002.1 - 3.3e-14 53.0 0.1 6e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain DUF4284 PF14112.6 EAX92003.1 - 0.032 15.2 2.9 0.045 14.7 2.7 1.4 1 1 0 1 1 1 0 Immunity protein 22 CUT PF02376.15 EAX92003.1 - 0.064 13.4 0.7 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 CUT domain Endotoxin_C2 PF18449.1 EAX92003.1 - 0.25 11.7 8.1 0.33 11.3 4.1 2.4 1 1 1 2 2 2 0 Delta endotoxin DUF1091 PF06477.13 EAX92004.1 - 0.047 14.2 5.6 10 6.7 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1091) Myb_DNA-binding PF00249.31 EAX92005.1 - 2.2e-18 66.2 0.0 4.5e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92005.1 - 9.4e-14 51.4 0.3 2.4e-13 50.1 0.1 1.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX92005.1 - 1.8e-05 24.6 0.1 0.0031 17.4 0.1 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX92005.1 - 0.032 14.4 0.0 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 EAX92005.1 - 0.038 14.1 0.4 0.056 13.6 0.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-binding PF00249.31 EAX92006.1 - 3.2e-27 94.4 4.4 6.1e-14 51.9 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92006.1 - 5e-19 68.3 4.8 3e-09 37.0 1.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX92006.1 - 0.0015 18.4 0.3 0.042 13.7 0.1 2.6 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAX92006.1 - 0.0026 18.0 3.1 1 9.7 0.2 2.3 1 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 EAX92006.1 - 0.014 15.5 2.2 2.4 8.4 0.6 3.0 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX92006.1 - 0.018 15.4 9.5 0.56 10.6 0.5 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tcell_CD4_C PF12104.8 EAX92006.1 - 0.022 14.7 0.3 0.053 13.4 0.3 1.6 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region SANT_DAMP1_like PF16282.5 EAX92006.1 - 0.032 14.4 0.5 0.032 14.4 0.5 1.9 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX92006.1 - 0.04 14.0 2.1 3.1 7.8 0.0 2.6 1 1 1 2 2 2 0 SLIDE ORC3_N PF07034.11 EAX92006.1 - 0.084 12.0 0.3 0.12 11.5 0.0 1.4 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Cpn60_TCP1 PF00118.24 EAX92007.1 - 2.9e-153 511.1 0.2 3.5e-153 510.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-binding PF00249.31 EAX92009.1 - 5.4e-29 100.1 0.4 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92009.1 - 1.4e-21 76.5 1.5 9.9e-13 48.1 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX92009.1 - 0.00024 20.9 2.1 0.00045 20.1 0.6 2.0 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX92009.1 - 0.00053 20.3 2.0 0.11 12.9 0.9 2.4 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX92009.1 - 0.0012 19.1 0.5 0.14 12.5 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_C1 PF00112.23 EAX92010.1 - 3.2e-26 92.8 3.6 3.5e-26 92.7 3.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PSP PF04046.16 EAX92011.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92012.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX92014.1 - 1e-50 169.6 35.8 5.8e-33 112.8 14.1 5.7 4 2 2 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX92014.1 - 0.035 13.8 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX92017.1 - 2.2e-153 508.6 13.0 2.8e-153 508.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX92017.1 - 0.4 11.0 2.8 1.5 9.2 0.0 3.0 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX92017.1 - 0.55 10.7 5.1 5.1 7.6 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX92018.1 - 1.9e-06 28.3 0.2 3.7e-06 27.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX92019.1 - 1e-29 102.6 0.3 2.4e-29 101.4 0.1 1.6 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX92020.1 - 9.7e-10 37.9 2.7 9.8e-10 37.9 1.0 1.8 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Ribosomal_S6e PF01092.19 EAX92020.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e PadR PF03551.14 EAX92021.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family GPS2_interact PF15784.5 EAX92022.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92022.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX92023.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3781 PF12636.7 EAX92024.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX92025.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92025.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX92026.1 - 0.022 14.7 10.4 0.03 14.3 10.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX92028.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX92029.1 - 0.013 15.9 0.4 0.016 15.6 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Birna_RdRp PF04197.12 EAX92029.1 - 0.084 11.2 1.9 0.086 11.2 1.9 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF2868 PF11067.8 EAX92029.1 - 1 8.8 4.9 1.1 8.7 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CBM_15 PF03426.14 EAX92030.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF2400 PF09674.10 EAX92030.1 - 0.075 13.0 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX92030.1 - 0.077 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX92031.1 - 4.2e-15 55.6 3.6 2.4e-14 53.1 3.0 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ribosomal_S6e PF01092.19 EAX92031.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e LRR_4 PF12799.7 EAX92032.1 - 0.5 10.9 5.8 0.91 10.0 0.1 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Cadherin PF00028.17 EAX92033.1 - 0.85 10.1 5.6 0.91 10.0 4.9 1.6 1 1 0 1 1 1 0 Cadherin domain FAA_hydro_N_2 PF18288.1 EAX92034.1 - 0.79 10.2 3.6 3.6 8.1 0.6 3.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 FlxA PF14282.6 EAX92035.1 - 0.0033 17.4 8.0 0.006 16.5 8.0 1.3 1 0 0 1 1 1 1 FlxA-like protein DUF3450 PF11932.8 EAX92035.1 - 0.0042 16.4 0.7 0.0055 16.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) AAA_13 PF13166.6 EAX92035.1 - 0.009 14.7 2.4 0.011 14.4 2.4 1.1 1 0 0 1 1 1 1 AAA domain Taxilin PF09728.9 EAX92035.1 - 0.0096 15.1 7.5 0.06 12.5 5.7 2.2 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4446 PF14584.6 EAX92035.1 - 0.016 15.2 1.2 0.029 14.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FapA PF03961.13 EAX92035.1 - 0.018 13.7 2.9 0.019 13.6 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 EAX92035.1 - 0.018 14.9 1.6 0.042 13.7 1.6 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mod_r PF07200.13 EAX92035.1 - 0.058 13.5 6.3 0.52 10.4 5.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 EAX92035.1 - 0.062 13.4 6.9 0.1 12.7 6.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 EAX92035.1 - 0.067 13.6 1.8 0.11 12.9 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF2968 PF11180.8 EAX92035.1 - 0.074 12.7 4.5 0.1 12.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) THOC7 PF05615.13 EAX92035.1 - 0.11 12.8 6.8 0.087 13.1 3.4 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.11 EAX92035.1 - 0.11 11.3 7.2 0.17 10.8 7.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EAX92035.1 - 0.12 12.6 0.2 0.24 11.7 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.6 EAX92035.1 - 0.14 12.5 16.0 0.14 12.6 12.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1843 PF08898.10 EAX92035.1 - 0.16 12.5 0.8 0.37 11.3 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) TRAF_BIRC3_bd PF16673.5 EAX92035.1 - 0.24 11.2 3.0 0.57 10.0 2.1 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF5398 PF17376.2 EAX92035.1 - 0.28 11.8 5.6 0.26 11.9 2.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5398) Atg14 PF10186.9 EAX92035.1 - 0.32 10.0 4.9 0.5 9.4 4.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 EAX92035.1 - 0.67 10.3 9.4 0.6 10.4 6.5 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 EAX92035.1 - 0.77 10.0 10.6 8.5 6.7 6.4 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Cnn_1N PF07989.11 EAX92035.1 - 0.89 9.8 9.1 3.4 7.9 9.1 2.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 EAX92035.1 - 1.5 8.1 5.3 2.2 7.6 5.3 1.2 1 0 0 1 1 1 0 FAM76 protein BST2 PF16716.5 EAX92035.1 - 2.5 8.8 7.3 6.5 7.4 7.3 1.8 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 T7SS_ESX_EspC PF10824.8 EAX92036.1 - 6.7 7.3 8.4 9.6 6.8 0.5 4.4 3 1 2 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm Bromodomain PF00439.25 EAX92037.1 - 2.1e-12 46.9 1.5 2.1e-12 46.9 1.5 1.9 2 1 0 2 2 2 1 Bromodomain DDE_Tnp_IS240 PF13610.6 EAX92037.1 - 0.04 14.1 0.8 0.07 13.3 0.8 1.3 1 0 0 1 1 1 0 DDE domain KH_9 PF17904.1 EAX92037.1 - 0.044 14.2 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 FMRP KH0 domain DUF445 PF04286.12 EAX92037.1 - 0.061 13.1 0.8 0.097 12.5 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Acyltransf_C PF16076.5 EAX92037.1 - 0.11 12.6 1.7 0.6 10.3 0.5 2.1 1 1 1 2 2 2 0 Acyltransferase C-terminus DUF3447 PF11929.8 EAX92038.1 - 3.5e-23 81.3 6.4 3.5e-23 81.3 6.4 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX92038.1 - 2e-22 79.6 3.7 1.4e-09 38.4 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92038.1 - 1.2e-20 73.6 1.1 3.2e-07 30.8 0.0 6.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92038.1 - 4.9e-14 51.1 4.0 0.018 15.5 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX92038.1 - 3.3e-13 49.6 1.0 4.1e-06 27.0 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX92038.1 - 4.5e-08 33.2 0.0 0.19 12.2 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat DrrA_P4M PF14860.6 EAX92038.1 - 9 6.2 10.4 11 5.9 0.1 2.9 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain KilA-N PF04383.13 EAX92039.1 - 9.7e-25 86.6 0.9 1.6e-24 85.9 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX92039.1 - 0.086 13.5 0.0 0.23 12.1 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX92040.1 - 8.1e-07 28.7 3.8 8.1e-07 28.7 3.8 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92040.1 - 1.4e-05 25.4 0.1 0.00014 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92040.1 - 6.6e-05 22.7 0.2 0.41 10.4 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92040.1 - 0.00051 20.1 2.9 0.0012 18.8 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX92040.1 - 0.0013 18.6 0.3 0.0028 17.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92040.1 - 0.0017 18.0 0.4 0.011 15.4 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) DEAD PF00270.29 EAX92040.1 - 0.0027 17.5 0.1 0.005 16.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAX92040.1 - 0.016 15.6 0.0 0.047 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX92040.1 - 0.079 12.5 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAX92040.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX92040.1 - 0.11 13.0 0.1 0.85 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX92040.1 - 0.18 12.2 3.0 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX92040.1 - 0.34 11.2 3.5 11 6.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) CENP-F_leu_zip PF10473.9 EAX92041.1 - 0.0056 16.7 8.0 0.0056 16.7 8.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1542 PF07564.11 EAX92041.1 - 0.037 14.1 1.5 0.037 14.1 1.5 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Fungal_TACC PF12709.7 EAX92041.1 - 0.11 12.9 1.0 0.11 12.9 1.0 4.3 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 EAX92041.1 - 0.13 11.1 25.7 0.68 8.8 8.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 EAX92041.1 - 0.7 10.1 18.7 0.13 12.5 8.0 2.6 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) SecD-TM1 PF13721.6 EAX92041.1 - 1.5 9.3 5.0 0.32 11.5 1.0 1.9 2 1 0 2 2 2 0 SecD export protein N-terminal TM region NPV_P10 PF05531.12 EAX92041.1 - 3.2 8.3 7.3 0.65 10.5 0.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SNF2_N PF00176.23 EAX92042.1 - 1.9e-59 201.1 0.0 5e-59 199.8 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX92042.1 - 6.5e-20 71.5 0.0 2.2e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EAX92042.1 - 1e-17 64.0 2.4 1.9e-16 59.9 0.2 2.8 2 0 0 2 2 2 1 Bromodomain ResIII PF04851.15 EAX92042.1 - 1.9e-08 34.5 0.2 3.2e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92042.1 - 4.3e-05 23.4 0.0 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EAX92042.1 - 0.00027 20.7 0.0 0.64 9.6 0.0 3.1 1 1 1 2 2 2 2 SWI2/SNF2 ATPase BLOC1_2 PF10046.9 EAX92042.1 - 1.7 9.0 15.1 17 5.8 8.6 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_C37 PF05416.12 EAX92042.1 - 5 5.5 9.4 0.11 11.1 0.9 2.3 3 0 0 3 3 3 0 Southampton virus-type processing peptidase Spectrin_like PF18373.1 EAX92043.1 - 0.002 18.1 0.7 0.0045 17.0 0.7 1.7 1 0 0 1 1 1 1 Spectrin like domain SOAR PF16533.5 EAX92043.1 - 0.33 11.0 8.2 2.3 8.2 4.3 2.1 1 1 1 2 2 2 0 STIM1 Orai1-activating region Tropomyosin_1 PF12718.7 EAX92043.1 - 0.78 9.9 19.2 1.1 9.4 19.2 1.2 1 0 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.10 EAX92043.1 - 4.4 7.5 13.6 5.9 7.1 13.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EAX92043.1 - 6.8 6.2 8.9 8.3 5.9 8.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 EAX92044.1 - 2.7e-67 226.9 0.0 8.2e-67 225.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92044.1 - 1.1e-49 169.1 0.0 2e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX92044.1 - 1.9e-05 23.6 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX92044.1 - 0.0075 15.9 0.5 0.065 12.8 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Cnd1 PF12717.7 EAX92044.1 - 0.0078 16.3 0.7 0.67 10.0 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 NDUF_C2 PF06374.11 EAX92044.1 - 0.027 14.6 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) KIX_2 PF16987.5 EAX92044.1 - 0.07 13.1 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 KIX domain Dimer_Tnp_hAT PF05699.14 EAX92044.1 - 0.093 12.5 0.6 0.8 9.5 0.0 2.7 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region Peptidase_C12 PF01088.21 EAX92044.1 - 2.3 7.9 4.1 2.8 7.6 0.3 2.6 2 1 1 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Guanylate_kin PF00625.21 EAX92047.1 - 1.3e-55 187.9 0.0 1.4e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase HTH_19 PF12844.7 EAX92047.1 - 0.01 15.8 0.9 0.019 15.0 0.9 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RsgA_GTPase PF03193.16 EAX92047.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF2096 PF09869.9 EAX92047.1 - 0.027 14.6 0.3 0.042 13.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) AAA_16 PF13191.6 EAX92047.1 - 0.032 14.6 0.1 0.062 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EAX92047.1 - 0.032 14.8 0.0 0.067 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAX92047.1 - 0.034 14.3 0.7 0.53 10.4 0.7 2.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX92047.1 - 0.042 14.4 0.0 0.077 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 EAX92047.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TROVE PF05731.11 EAX92047.1 - 0.077 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 TROVE domain MULE PF10551.9 EAX92048.1 - 2.2e-11 44.0 0.1 4.4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX92048.1 - 0.064 13.7 0.5 2 8.8 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAX92048.1 - 0.11 12.6 3.6 0.21 11.7 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain LRR_5 PF13306.6 EAX92050.1 - 9.5e-142 465.3 58.6 1.7e-37 128.2 5.1 3.7 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92050.1 - 2.2e-17 62.5 5.8 0.0054 16.5 0.0 6.9 2 1 5 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAX92050.1 - 0.26 11.7 14.8 0.081 13.4 2.4 5.0 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) RICH PF05062.12 EAX92050.1 - 7.2 7.0 6.6 3.1 8.2 0.0 3.2 4 0 0 4 4 4 0 RICH domain DUF3839 PF12943.7 EAX92051.1 - 2.5e-16 59.9 3.1 4e-16 59.2 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX92051.1 - 0.048 14.0 0.3 0.13 12.5 0.1 1.9 1 1 1 2 2 2 0 PRD domain ZapB PF06005.12 EAX92051.1 - 0.063 13.7 0.3 0.53 10.8 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF3839 PF12943.7 EAX92052.1 - 2.7e-117 390.5 6.8 3.3e-117 390.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX92053.1 - 1.1e-25 89.5 40.4 2.5e-09 37.0 5.7 5.3 5 0 0 5 5 5 3 Phage tail repeat like EMP24_GP25L PF01105.24 EAX92053.1 - 0.0066 16.4 10.8 0.97 9.4 1.3 3.5 2 1 1 3 3 3 2 emp24/gp25L/p24 family/GOLD PH_TFIIH PF08567.11 EAX92053.1 - 0.63 10.4 3.4 89 3.5 0.1 3.4 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain PA28_alpha PF02251.18 EAX92053.1 - 0.72 9.9 7.3 7.8 6.6 0.3 3.2 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit DUF1722 PF08349.11 EAX92053.1 - 0.74 10.1 4.8 2.4 8.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Ferritin PF00210.24 EAX92053.1 - 0.77 9.7 7.2 11 5.9 0.2 2.6 2 0 0 2 2 2 0 Ferritin-like domain RraB PF06877.11 EAX92053.1 - 0.79 10.5 7.6 42 4.9 0.2 3.6 2 1 1 3 3 3 0 Regulator of ribonuclease activity B GUN4_N PF16416.5 EAX92053.1 - 1.1 9.3 7.6 8 6.5 0.3 4.0 2 1 2 4 4 4 0 ARM-like repeat domain, GUN4-N terminal KinB_sensor PF16767.5 EAX92053.1 - 2.2 8.8 5.5 9.8 6.7 0.3 3.2 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF5082 PF16888.5 EAX92053.1 - 3.1 8.1 21.0 2.3 8.5 10.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) RecG_N PF17190.4 EAX92053.1 - 5.3 7.9 14.7 2.1 9.1 0.6 4.1 3 1 0 4 4 4 0 RecG N-terminal helical domain L27 PF02828.16 EAX92053.1 - 7.8 6.4 6.0 14 5.5 0.1 3.5 4 1 1 5 5 4 0 L27 domain DUF1690 PF07956.11 EAX92053.1 - 8.7 6.8 16.4 4.7 7.6 6.9 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF4107 PF13389.6 EAX92056.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_2 PF12796.7 EAX92058.1 - 2.3e-06 28.1 0.1 0.025 15.2 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX92058.1 - 0.0027 17.6 2.9 0.0027 17.6 2.9 3.3 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX92058.1 - 0.0031 17.9 0.1 9.8 7.1 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX92058.1 - 0.0038 17.8 0.1 5.8 7.6 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) KRTAP7 PF15034.6 EAX92058.1 - 0.11 13.4 0.0 0.45 11.5 0.0 1.9 2 0 0 2 2 2 0 KRTAP type 7 family PDEase_I PF00233.19 EAX92060.1 - 2.2e-29 102.9 0.7 2.2e-29 102.9 0.7 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase ETRAMP PF09716.10 EAX92060.1 - 0.4 10.8 1.9 1.3 9.1 0.7 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) COesterase PF00135.28 EAX92061.1 - 9.2e-99 331.6 0.0 5.3e-81 273.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAX92061.1 - 9e-08 32.2 0.0 5.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAX92061.1 - 0.011 16.3 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EAX92061.1 - 0.012 15.3 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 EAX92061.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_3 PF00933.21 EAX92061.1 - 0.25 10.7 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Arf PF00025.21 EAX92062.1 - 1e-10 41.3 0.0 2.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX92062.1 - 1.5e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EAX92062.1 - 0.0007 20.0 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EAX92062.1 - 0.0015 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX92062.1 - 0.0021 17.6 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAX92062.1 - 0.0029 17.0 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EAX92062.1 - 0.0049 16.1 0.0 0.015 14.5 0.0 1.7 1 1 1 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 EAX92062.1 - 0.0059 17.1 0.0 0.0084 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX92062.1 - 0.0087 16.3 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX92062.1 - 0.02 15.3 0.0 0.031 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EAX92062.1 - 0.042 14.4 0.0 0.05 14.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EAX92062.1 - 0.062 12.8 0.0 0.69 9.4 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B NOG1 PF06858.14 EAX92062.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_5 PF07728.14 EAX92062.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAX92062.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thioredoxin PF00085.20 EAX92063.1 - 1.1e-20 73.5 0.1 1.4e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX92063.1 - 2e-05 25.0 0.2 0.0004 20.8 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX92063.1 - 4.3e-05 23.8 0.1 0.2 12.0 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EAX92063.1 - 0.00093 19.1 0.1 0.0016 18.4 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EAX92063.1 - 0.007 16.6 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 EAX92063.1 - 0.018 15.2 0.1 0.046 13.9 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EAX92063.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 EAX92063.1 - 0.071 13.5 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 EAX92063.1 - 0.071 12.8 0.3 1.3 8.7 0.2 2.1 1 1 1 2 2 2 0 Redoxin OST3_OST6 PF04756.13 EAX92063.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glyco_hydro_53 PF07745.13 EAX92063.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 DUF3447 PF11929.8 EAX92064.1 - 1.7e-39 133.6 8.4 1.7e-39 133.6 8.4 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX92064.1 - 2.9e-35 120.2 7.3 4.7e-10 39.8 0.0 7.0 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92064.1 - 4.5e-30 104.1 12.9 1.2e-14 54.7 2.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92064.1 - 8.2e-30 101.9 2.6 1.1e-06 28.8 0.2 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAX92064.1 - 1e-24 83.9 7.5 2.7e-05 24.2 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX92064.1 - 1.7e-21 76.0 5.7 3.6e-09 36.7 0.3 5.5 3 2 3 6 6 6 3 Ankyrin repeats (many copies) NRDE-2 PF08424.10 EAX92064.1 - 0.1 11.7 0.2 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference ACP53EA PF06313.11 EAX92064.1 - 0.23 11.7 2.5 0.75 10.0 0.6 2.4 2 0 0 2 2 2 0 Drosophila ACP53EA protein Tup_N PF08581.10 EAX92064.1 - 2.3 8.6 10.3 4.2 7.8 2.2 3.1 3 0 0 3 3 3 0 Tup N-terminal DUF4108 PF13390.6 EAX92065.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX92066.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX92067.1 - 7e-07 29.0 2.8 7e-07 29.0 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92067.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX92067.1 - 0.00016 21.8 3.0 0.00036 20.6 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX92067.1 - 0.00025 20.9 0.3 0.49 10.1 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX92067.1 - 0.00065 19.5 0.1 0.0013 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92067.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92067.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92067.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92067.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX92067.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX92067.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KilA-N PF04383.13 EAX92068.1 - 1.1e-34 118.6 0.6 2.3e-34 117.6 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX92068.1 - 0.015 16.0 0.0 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family DUF4107 PF13389.6 EAX92071.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) FYVE_2 PF02318.16 EAX92072.1 - 0.036 14.3 0.2 0.061 13.5 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Nucleoside_tran PF01733.18 EAX92073.1 - 2.2e-26 93.0 29.7 1.1e-21 77.5 7.5 2.5 2 1 1 3 3 3 2 Nucleoside transporter 3Beta_HSD PF01073.19 EAX92074.1 - 6.1e-14 51.7 1.1 9.5e-14 51.1 1.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAX92074.1 - 3.6e-12 46.3 0.0 5.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAX92074.1 - 1.1e-08 35.1 0.0 2.2e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EAX92074.1 - 3.1e-08 33.4 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAX92074.1 - 3e-07 29.9 0.2 7.4e-07 28.6 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EAX92074.1 - 4.8e-07 29.2 0.4 2.8e-05 23.4 0.2 3.0 2 1 0 2 2 2 1 Male sterility protein DUF4379 PF14311.6 EAX92074.1 - 0.00024 21.4 1.3 0.00053 20.3 1.3 1.6 1 0 0 1 1 1 1 Probable Zinc-ribbon domain DXP_reductoisom PF02670.16 EAX92074.1 - 0.007 17.1 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rax2 PF12768.7 EAX92074.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity adh_short PF00106.25 EAX92074.1 - 0.051 13.0 0.2 0.11 11.9 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 EAX92074.1 - 0.068 12.7 0.1 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF4770 PF15994.5 EAX92075.1 - 0.011 16.0 1.3 0.013 15.7 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TUDOR PF00567.24 EAX92075.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Tudor domain PSP PF04046.16 EAX92076.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92077.1 - 0.13 13.0 7.4 6.3 7.9 0.9 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX92077.1 - 5.9 6.9 8.2 5.9 6.9 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3839 PF12943.7 EAX92078.1 - 1e-155 516.2 12.1 1.3e-155 515.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX92078.1 - 0.065 13.7 1.2 0.33 11.4 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX92078.1 - 0.28 11.7 5.1 2.6 8.6 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX92078.1 - 0.74 10.4 5.8 0.3 11.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A32 PF04665.12 EAX92079.1 - 3.9e-06 26.5 3.8 3.9e-06 26.5 3.8 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX92079.1 - 3.1e-05 23.8 0.3 0.24 11.1 0.1 2.7 1 1 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX92079.1 - 6.4e-05 23.2 0.2 0.00041 20.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX92079.1 - 9.8e-05 22.4 3.0 0.00018 21.6 2.9 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92079.1 - 0.00056 19.7 0.1 0.00098 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92079.1 - 0.0012 18.7 0.5 0.0021 17.9 0.5 1.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92079.1 - 0.0017 18.0 0.5 0.012 15.2 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92079.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX92079.1 - 0.064 13.7 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX92079.1 - 0.065 12.8 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX92079.1 - 0.085 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF3783 PF12646.7 EAX92079.1 - 0.24 11.4 2.1 1.9 8.5 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF1827 PF08860.10 EAX92079.1 - 0.39 11.0 4.7 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Ank_4 PF13637.6 EAX92081.1 - 6.3e-31 106.4 1.6 3.6e-14 52.9 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92081.1 - 7.8e-26 89.8 7.1 2.1e-25 88.4 7.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX92081.1 - 5.9e-25 86.6 0.2 5.9e-07 29.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAX92081.1 - 1.5e-22 80.0 1.8 6e-15 55.6 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92081.1 - 5.1e-20 71.3 1.8 5.7e-07 29.7 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92081.1 - 6.2e-19 66.1 1.2 0.0013 19.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX92082.1 - 9.1e-19 67.6 0.9 1.5e-11 44.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX92082.1 - 4.7e-12 45.8 1.2 1.1e-06 28.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX92082.1 - 6.3e-12 45.9 1.7 3.8e-11 43.4 1.7 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92082.1 - 2.7e-11 43.5 0.6 4.5e-11 42.8 0.2 1.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92082.1 - 2.7e-10 39.6 0.3 9.9e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Glyco_hydro_31 PF01055.26 EAX92083.1 - 3.7e-119 398.8 9.6 3.7e-119 398.8 9.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAX92083.1 - 6.6e-18 64.8 2.4 1.7e-15 57.1 0.1 3.6 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EAX92083.1 - 9.8e-05 22.6 0.1 0.00044 20.5 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 EAX92083.1 - 0.0061 16.8 0.7 0.014 15.7 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) NtCtMGAM_N PF16863.5 EAX92083.1 - 0.075 13.2 1.9 0.17 12.1 1.9 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase ADAM_spacer1 PF05986.14 EAX92084.1 - 0.097 12.7 0.2 14 5.8 0.0 2.4 2 0 0 2 2 2 0 ADAM-TS Spacer 1 Ank_2 PF12796.7 EAX92086.1 - 5.3e-71 235.2 4.0 7.1e-21 74.6 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92086.1 - 1.9e-38 130.0 0.0 4e-09 36.6 0.0 6.8 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX92086.1 - 4.2e-37 125.0 0.0 1.3e-05 25.4 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX92086.1 - 2.2e-34 117.4 0.0 1.4e-10 41.5 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92086.1 - 6e-34 112.2 0.0 0.00033 20.9 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Vps4_C PF09336.10 EAX92086.1 - 0.073 13.1 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DNA_pol_A_exo1 PF01612.20 EAX92087.1 - 8.8e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease SPOUT_MTase PF02590.17 EAX92087.1 - 0.036 14.0 0.2 0.27 11.2 0.0 2.1 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase SMN PF06003.12 EAX92087.1 - 0.24 10.6 1.3 0.37 10.0 1.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pkinase PF00069.25 EAX92088.1 - 1.3e-51 175.5 0.0 1.7e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92088.1 - 3.3e-35 121.6 0.0 4e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX92088.1 - 2.8e-09 36.7 0.0 5.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX92088.1 - 0.0081 15.1 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAX92088.1 - 0.011 14.8 1.5 0.034 13.2 1.1 1.8 1 1 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EAX92088.1 - 0.048 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EAX92089.1 - 9.3e-31 105.8 3.9 5.7e-16 58.4 1.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92089.1 - 1.4e-24 86.0 2.6 1.2e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX92089.1 - 3.8e-07 30.1 0.1 0.0018 18.3 0.0 2.1 1 1 1 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EAX92089.1 - 7.4e-05 23.0 1.5 0.044 14.1 0.1 2.8 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 EAX92089.1 - 0.012 15.5 0.3 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX92089.1 - 0.022 15.1 4.9 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain F5_F8_type_C PF00754.25 EAX92090.1 - 0.0026 17.9 0.0 0.0082 16.3 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain DUF2677 PF10838.8 EAX92090.1 - 0.022 14.7 0.1 0.03 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) Pkinase PF00069.25 EAX92091.1 - 8e-35 120.5 0.0 1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92091.1 - 6.8e-24 84.6 0.0 9.3e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX92091.1 - 4.9e-05 22.8 0.0 0.00015 21.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX92091.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cyt-b5 PF00173.28 EAX92092.1 - 3.1e-20 72.1 0.0 3.7e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myb_DNA-bind_6 PF13921.6 EAX92093.1 - 4.8e-11 42.7 1.4 1.3e-05 25.4 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX92093.1 - 1.6e-10 41.0 1.9 2.9e-08 33.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX92093.1 - 0.023 14.6 0.5 0.037 13.9 0.5 1.4 1 0 0 1 1 1 0 Myb DNA-binding like SLY PF12485.8 EAX92093.1 - 0.16 12.7 1.6 0.23 12.2 1.6 1.5 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein HMG_box_2 PF09011.10 EAX92093.1 - 0.27 11.8 2.1 4.4 8.0 0.1 2.5 1 1 1 2 2 2 0 HMG-box domain Porin_4 PF13609.6 EAX92095.1 - 2.5e-08 34.1 0.0 0.0013 18.6 0.0 3.1 1 1 1 2 2 2 2 Gram-negative porin NinB PF05772.12 EAX92095.1 - 0.087 12.6 12.1 1.9 8.3 0.3 3.6 1 1 3 4 4 4 0 NinB protein Cyclophil_like2 PF18050.1 EAX92095.1 - 0.23 11.4 1.8 87 3.1 0.0 4.0 1 1 3 4 4 4 0 Cyclophilin-like family MIF PF01187.18 EAX92096.1 - 1.9e-07 31.4 0.0 2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EAX92096.1 - 1.4e-05 24.9 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 EAX92096.1 - 0.012 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Tautomerase enzyme DltD PF04914.12 EAX92096.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.0 1 0 0 1 1 1 0 DltD protein tRNA-synt_2b PF00587.25 EAX92098.1 - 2.2e-33 115.7 0.1 5.8e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAX92098.1 - 8.3e-11 42.1 6.3 1.6e-10 41.1 6.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 EAX92098.1 - 0.0045 16.6 1.5 0.0093 15.6 1.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Leu_zip PF15294.6 EAX92098.1 - 0.027 14.0 2.2 0.045 13.3 2.2 1.3 1 0 0 1 1 1 0 Leucine zipper APG6_N PF17675.1 EAX92098.1 - 0.048 14.2 4.2 0.11 13.0 4.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EAX92098.1 - 0.05 12.5 4.9 0.076 11.9 4.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 EAX92098.1 - 0.1 12.6 1.2 0.19 11.8 1.2 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4376 PF14301.6 EAX92098.1 - 0.14 12.5 0.3 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Uds1 PF15456.6 EAX92098.1 - 0.15 12.3 1.2 0.28 11.3 1.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF4407 PF14362.6 EAX92098.1 - 0.15 11.4 1.9 0.22 10.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlgN PF05130.12 EAX92098.1 - 0.16 12.5 1.4 0.44 11.0 0.1 2.1 2 0 0 2 2 2 0 FlgN protein SKA2 PF16740.5 EAX92098.1 - 0.32 10.8 2.4 0.62 9.9 1.7 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 HIP1_clath_bdg PF16515.5 EAX92098.1 - 1.2 9.8 5.1 1.1 9.9 1.0 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Chlam_PMP PF02415.17 EAX92099.1 - 0.066 13.7 7.4 18 6.1 1.1 5.1 4 1 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Guanylate_cyc PF00211.20 EAX92100.1 - 8.5e-43 146.1 0.1 1.7e-42 145.1 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX92100.1 - 1.3e-11 44.7 2.2 5.4e-11 42.7 1.8 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX92100.1 - 0.00016 21.7 0.2 0.00043 20.3 0.2 1.7 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX92100.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated PAS_4 PF08448.10 EAX92100.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 PAS fold DUF1884 PF08967.10 EAX92100.1 - 0.11 12.8 0.5 1.9 8.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) DUF3447 PF11929.8 EAX92101.1 - 8.2e-35 118.6 5.2 8.2e-35 118.6 5.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX92101.1 - 6.3e-06 26.7 0.1 0.001 19.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92101.1 - 0.00078 20.0 1.6 0.67 10.6 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92101.1 - 0.02 15.4 0.3 79 4.3 0.0 4.2 3 1 1 4 4 4 0 Ankyrin repeat GPS2_interact PF15784.5 EAX92103.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92103.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BACK PF07707.15 EAX92104.1 - 0.00059 19.9 2.1 0.00089 19.3 1.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Gln-synt_C-ter PF18318.1 EAX92104.1 - 0.06 13.2 1.7 0.28 11.1 0.2 2.4 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain YvrJ PF12841.7 EAX92106.1 - 0.45 10.1 1.6 4.7 6.8 0.0 3.1 2 0 0 2 2 2 0 YvrJ protein family Apolipoprotein PF01442.18 EAX92106.1 - 8.2 6.3 69.7 0.014 15.3 8.8 6.8 2 1 4 6 6 6 0 Apolipoprotein A1/A4/E domain Podoplanin PF05808.11 EAX92107.1 - 1.8e-07 31.4 1.4 2e-07 31.3 1.4 1.3 1 1 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 EAX92107.1 - 0.00018 22.0 0.1 0.00027 21.5 0.1 1.4 1 1 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 EAX92107.1 - 0.00027 19.9 0.0 0.00034 19.6 0.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Orf78 PF06024.12 EAX92107.1 - 0.00029 21.1 0.3 0.00069 19.9 0.0 1.7 2 1 0 2 2 2 1 Orf78 (ac78) DUF4448 PF14610.6 EAX92107.1 - 0.0013 18.6 0.1 0.0017 18.2 0.1 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2207 PF09972.9 EAX92107.1 - 0.0021 16.9 0.2 0.0036 16.1 0.2 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 EAX92107.1 - 0.0024 17.6 1.1 0.0037 17.0 1.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Amnionless PF14828.6 EAX92107.1 - 0.0032 16.4 0.0 0.0037 16.2 0.0 1.1 1 0 0 1 1 1 1 Amnionless YebO PF13974.6 EAX92107.1 - 0.0047 17.0 3.5 0.022 14.8 0.2 2.6 2 0 0 2 2 2 1 YebO-like protein DUF5305 PF17231.2 EAX92107.1 - 0.011 15.1 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) CCSMST1 PF15013.6 EAX92107.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family Otopetrin PF03189.13 EAX92107.1 - 0.021 13.7 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Syndecan PF01034.20 EAX92107.1 - 0.025 14.5 0.3 0.056 13.4 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain DUF4366 PF14283.6 EAX92107.1 - 0.027 14.5 0.7 0.034 14.2 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Mid2 PF04478.12 EAX92107.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 EAX92107.1 - 0.041 14.1 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Rax2 PF12768.7 EAX92107.1 - 0.047 13.2 0.1 0.086 12.3 0.1 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.6 EAX92107.1 - 0.085 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM132D_C PF15706.5 EAX92107.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MtrF PF09472.10 EAX92107.1 - 0.38 10.2 3.2 0.71 9.3 3.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SseC PF04888.12 EAX92107.1 - 1.5 8.4 5.8 0.46 10.0 2.5 1.7 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family EphA2_TM PF14575.6 EAX92107.1 - 7.1 7.6 6.0 1 10.3 0.4 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EDR1 PF14381.6 EAX92108.1 - 2.8e-22 79.4 0.1 3.4e-21 75.9 0.1 2.3 1 1 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Arm PF00514.23 EAX92108.1 - 5.8e-07 29.3 3.8 0.022 14.8 0.0 6.6 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EAX92108.1 - 0.0082 14.8 12.6 0.07 11.7 0.5 3.6 2 1 1 3 3 3 2 Adaptin N terminal region Orthopox_F14 PF06076.12 EAX92108.1 - 0.045 14.0 0.6 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Orthopoxvirus F14 protein DUF3361 PF11841.8 EAX92108.1 - 0.08 12.9 13.2 0.21 11.5 2.5 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) RICTOR_V PF14668.6 EAX92108.1 - 0.14 12.4 1.6 0.65 10.3 0.0 2.9 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Ank_2 PF12796.7 EAX92109.1 - 6.7e-61 202.9 24.7 2.7e-15 56.7 0.7 6.0 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92109.1 - 1.5e-50 167.5 7.5 2.9e-06 27.4 0.0 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EAX92109.1 - 3e-44 148.8 10.6 3.7e-10 40.1 0.0 8.4 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92109.1 - 2.3e-41 135.0 6.3 0.00054 20.2 0.0 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX92109.1 - 1.4e-34 117.7 5.1 5.5e-08 32.9 0.0 6.6 5 1 2 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92109.1 - 6.3e-21 74.1 25.1 5.1e-20 71.2 7.9 5.4 4 1 2 6 6 6 2 Domain of unknown function (DUF3447) LRR_5 PF13306.6 EAX92111.1 - 2e-18 66.6 2.6 2e-18 66.6 2.6 1.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92111.1 - 2e-06 27.4 0.6 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat Gly_rich PF12810.7 EAX92112.1 - 2.5e-15 57.1 34.1 3.2e-15 56.7 34.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX92113.1 - 1e-43 150.1 27.0 1.2e-43 149.8 27.0 1.0 1 0 0 1 1 1 1 Glycine rich protein PSP PF04046.16 EAX92114.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92115.1 - 0.083 13.5 5.7 11 7.2 0.2 3.3 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX92117.1 - 4.2e-135 448.8 10.4 5.1e-135 448.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX92117.1 - 0.049 14.1 1.9 0.11 13.0 0.4 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX92117.1 - 0.093 13.2 0.5 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX92117.1 - 0.77 10.3 6.8 5.7 7.5 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PSP PF04046.16 EAX92118.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92119.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX92120.1 - 8.8e-263 871.8 76.9 5e-141 470.7 36.7 4.4 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX92120.1 - 0.012 15.9 1.9 0.15 12.4 0.2 3.0 3 0 0 3 3 3 0 Kidney androgen-regulated Motile_Sperm PF00635.26 EAX92121.1 - 4.2e-05 23.4 0.7 0.00012 21.8 0.7 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Exo_endo_phos PF03372.23 EAX92121.1 - 0.00057 19.5 0.0 0.001 18.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.6 EAX92121.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Ank_2 PF12796.7 EAX92122.1 - 4.7e-49 164.9 21.1 9.4e-17 61.4 0.8 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX92122.1 - 3.4e-39 132.7 8.0 3.4e-39 132.7 8.0 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX92122.1 - 1.9e-33 114.4 6.2 7e-08 32.9 0.0 6.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92122.1 - 2.8e-29 100.8 5.7 7.6e-10 38.8 0.1 5.4 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX92122.1 - 9.4e-28 95.4 1.0 3.4e-05 24.1 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX92122.1 - 2e-19 67.6 4.3 0.046 14.3 0.0 8.2 6 1 2 8 8 8 4 Ankyrin repeat DUF4231 PF14015.6 EAX92122.1 - 0.01 16.3 2.9 13 6.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) MetallophosN PF16371.5 EAX92122.1 - 0.02 15.2 0.0 29 5.0 0.0 3.8 2 1 2 4 4 4 0 N terminal of Calcineurin-like phosphoesterase DUF3023 PF11224.8 EAX92122.1 - 0.03 14.2 0.1 0.068 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) PH_8 PF15409.6 EAX92122.1 - 0.33 11.3 2.2 21 5.5 0.3 3.8 2 1 3 5 5 5 0 Pleckstrin homology domain DUF5048 PF16467.5 EAX92122.1 - 0.65 10.3 4.5 12 6.3 0.1 3.9 2 1 1 4 4 4 0 Domain of unknown function (DUF5048) DUF2373 PF10180.9 EAX92122.1 - 0.73 9.7 8.0 95 2.9 0.5 4.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2373) ubiquitin PF00240.23 EAX92125.1 - 3.8e-19 68.2 0.1 4.1e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX92125.1 - 1.8e-10 40.5 0.6 2e-10 40.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX92125.1 - 0.0016 18.3 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EAX92125.1 - 0.18 11.8 0.4 15 5.7 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ank_2 PF12796.7 EAX92127.1 - 0.00045 20.8 0.3 1.9 9.1 0.1 2.9 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX92127.1 - 0.00064 19.6 1.7 0.00064 19.6 1.7 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX92127.1 - 0.0026 18.1 0.2 15 6.5 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat TcpS PF17456.2 EAX92127.1 - 0.0059 16.7 0.5 0.014 15.5 0.1 1.8 1 1 0 1 1 1 1 Toxin-coregulated pilus protein S Ank_4 PF13637.6 EAX92127.1 - 0.012 16.2 0.3 11 6.7 0.0 3.8 3 2 2 5 5 5 0 Ankyrin repeats (many copies) Band_7_1 PF13421.6 EAX92127.1 - 0.02 14.6 0.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 SPFH domain-Band 7 family CUE PF02845.16 EAX92127.1 - 0.12 12.1 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 CUE domain DUF3447 PF11929.8 EAX92128.1 - 1.4e-05 25.0 3.3 1.4e-05 25.0 3.3 3.2 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX92128.1 - 0.00027 21.5 0.0 0.73 10.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92128.1 - 0.0051 17.4 0.1 1.8 9.3 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92128.1 - 0.16 12.4 0.4 4.1 7.8 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) EphA2_TM PF14575.6 EAX92129.1 - 0.014 16.3 0.3 7.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX92129.1 - 0.016 15.1 3.9 0.059 13.3 0.3 2.8 3 0 0 3 3 3 0 Syndecan domain VSP PF03302.13 EAX92129.1 - 0.037 12.9 1.3 0.078 11.8 1.3 1.5 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 EAX92129.1 - 0.044 13.5 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CCSMST1 PF15013.6 EAX92129.1 - 0.045 13.9 0.2 0.16 12.1 0.2 1.9 1 0 0 1 1 1 0 CCSMST1 family Podoplanin PF05808.11 EAX92129.1 - 0.051 13.7 2.3 0.15 12.2 2.3 1.8 1 1 0 1 1 1 0 Podoplanin MMM1 PF10296.9 EAX92129.1 - 0.1 11.6 0.5 0.2 10.7 0.5 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF4690 PF15756.5 EAX92129.1 - 0.45 11.1 3.1 0.9 10.2 2.2 2.0 1 1 0 1 1 1 0 Small Novel Rich in Cartilage YebO PF13974.6 EAX92129.1 - 6 7.0 7.7 0.65 10.1 2.1 2.2 2 0 0 2 2 2 0 YebO-like protein DUF4912 PF16258.5 EAX92130.1 - 0.01 16.1 0.1 0.099 12.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4912) Syndecan PF01034.20 EAX92130.1 - 0.011 15.6 0.3 0.045 13.7 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain DUF4690 PF15756.5 EAX92130.1 - 0.013 16.1 0.5 0.04 14.5 0.5 1.9 1 1 0 1 1 1 0 Small Novel Rich in Cartilage VSP PF03302.13 EAX92130.1 - 0.016 14.0 0.8 0.032 13.1 0.8 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 EAX92130.1 - 0.17 12.0 2.0 0.48 10.5 2.0 1.8 1 1 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 EAX92130.1 - 0.21 11.4 1.6 0.38 10.6 1.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 YebO PF13974.6 EAX92130.1 - 0.28 11.3 2.5 0.84 9.8 2.5 1.8 1 0 0 1 1 1 0 YebO-like protein ABC_tran PF00005.27 EAX92131.1 - 5.2e-26 91.8 1.6 5.7e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX92131.1 - 2e-24 86.4 25.0 3.5e-24 85.5 25.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAX92131.1 - 2.5e-06 27.5 5.0 0.0049 16.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX92131.1 - 0.0014 18.1 0.0 0.069 12.6 1.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAX92131.1 - 0.18 12.1 0.0 0.59 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sensor PF13796.6 EAX92131.1 - 0.28 11.2 1.2 2.6 8.1 1.0 2.3 1 1 0 1 1 1 0 Putative sensor CDC45 PF02724.14 EAX92131.1 - 6.7 4.9 15.4 9.6 4.4 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 EAX92132.1 - 2.4e-28 99.3 0.0 4.1e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX92132.1 - 1.5e-08 34.8 1.1 0.0038 17.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX92132.1 - 5.9e-06 25.9 0.7 0.021 14.3 0.2 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EAX92132.1 - 9.2e-05 21.7 43.7 0.00017 20.8 43.6 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EAX92132.1 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EAX92132.1 - 0.00018 21.2 0.1 0.00046 19.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EAX92132.1 - 0.00027 21.5 1.7 0.001 19.6 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAX92132.1 - 0.0012 18.6 0.3 0.0012 18.6 0.3 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EAX92132.1 - 0.0073 16.7 0.1 0.016 15.6 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX92132.1 - 0.016 15.5 0.0 0.093 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAX92132.1 - 0.022 14.8 0.2 0.065 13.3 0.2 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EAX92132.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX92132.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Adipogenin PF15202.6 EAX92132.1 - 0.033 14.2 0.1 0.033 14.2 0.1 2.5 2 0 0 2 2 2 0 Adipogenin Rad17 PF03215.15 EAX92132.1 - 0.038 13.9 0.8 0.14 12.0 0.1 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EAX92132.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_27 PF13514.6 EAX92132.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX92132.1 - 0.087 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX92132.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EAX92132.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pkinase_Tyr PF07714.17 EAX92134.1 - 1.1e-55 188.7 0.0 1.8e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX92134.1 - 3.8e-54 183.8 0.0 6.2e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EAX92134.1 - 0.083 11.8 0.0 0.22 10.4 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Ank_2 PF12796.7 EAX92135.1 - 6.3e-54 180.5 0.3 3.4e-18 66.0 0.1 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92135.1 - 1.9e-37 126.0 2.0 7.7e-08 32.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX92135.1 - 6.6e-33 112.3 0.1 1.9e-08 34.4 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92135.1 - 8.8e-30 99.4 0.4 6.7e-06 26.1 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX92135.1 - 3.4e-29 100.8 0.0 2.1e-08 34.5 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DX PF01666.17 EAX92136.1 - 0.17 12.4 0.4 3.5 8.1 0.1 2.5 2 1 0 2 2 2 0 DX module GreA_GreB PF01272.19 EAX92137.1 - 3.3e-05 23.7 21.8 1.1 9.2 0.2 10.2 11 0 0 11 11 11 4 Transcription elongation factor, GreA/GreB, C-term DUF4516 PF14990.6 EAX92137.1 - 0.0018 17.9 0.0 3.7 7.4 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4516) Tho2 PF11262.8 EAX92138.1 - 0.013 14.7 2.4 0.015 14.5 2.4 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ATG16 PF08614.11 EAX92140.1 - 5.3e-05 23.5 11.2 9e-05 22.8 11.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EAX92140.1 - 0.025 15.1 14.3 0.038 14.5 14.3 1.2 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 EAX92140.1 - 0.19 10.6 15.1 0.3 9.9 15.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EAX92140.1 - 0.34 10.4 5.9 0.47 10.0 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EAX92140.1 - 0.47 9.5 11.9 0.69 8.9 11.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 EAX92140.1 - 2.2 7.9 9.2 4.6 6.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HIP1_clath_bdg PF16515.5 EAX92140.1 - 3.5 8.3 11.6 6 7.5 10.6 1.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CC2-LZ PF16516.5 EAX92140.1 - 3.9 7.9 15.1 0.87 10.0 9.1 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_15 PF13175.6 EAX92140.1 - 4.8 6.8 20.9 10 5.7 20.9 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mod_r PF07200.13 EAX92141.1 - 0.0027 17.8 11.9 0.0027 17.8 11.9 7.0 5 2 3 8 8 8 1 Modifier of rudimentary (Mod(r)) protein DAGK_acc PF00609.19 EAX92141.1 - 0.018 15.4 0.7 0.018 15.4 0.7 2.9 3 0 0 3 3 3 0 Diacylglycerol kinase accessory domain Ribosomal_L18A PF01775.17 EAX92142.1 - 8.4e-44 148.6 0.1 1.1e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Bse634I PF07832.11 EAX92142.1 - 0.065 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease DUF148 PF02520.17 EAX92143.1 - 1.1 9.4 3.8 0.48 10.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 WD40 PF00400.32 EAX92144.1 - 1.1e-14 54.6 3.4 0.0029 18.4 0.7 7.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX92144.1 - 2.1e-09 37.6 0.7 0.97 9.8 0.0 5.9 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain CASP_C PF08172.12 EAX92145.1 - 0.0014 18.1 0.3 0.0019 17.6 0.3 1.3 1 0 0 1 1 1 1 CASP C terminal RTBV_P46 PF06216.11 EAX92145.1 - 0.0037 16.2 0.0 0.0041 16.0 0.0 1.0 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein TSC22 PF01166.18 EAX92145.1 - 0.0044 17.3 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family SlyX PF04102.12 EAX92145.1 - 0.0089 16.6 0.4 0.0089 16.6 0.4 1.9 2 0 0 2 2 2 1 SlyX TolA_bind_tri PF16331.5 EAX92145.1 - 0.011 15.8 1.4 0.011 15.8 1.4 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation APC_N_CC PF16689.5 EAX92145.1 - 0.015 15.3 0.7 0.039 14.0 0.2 1.9 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 EAX92145.1 - 0.033 14.3 0.4 0.08 13.1 0.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 EAX92145.1 - 0.056 13.5 3.4 0.11 12.5 3.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PSP PF04046.16 EAX92146.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92147.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX92148.1 - 0.029 14.9 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX92148.1 - 0.26 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX92149.1 - 1.8e-156 518.7 15.4 2.3e-156 518.4 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX92149.1 - 0.58 10.5 3.1 2.9 8.2 0.0 3.1 2 2 1 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX92149.1 - 3.9 8.0 8.2 2.1 8.8 1.0 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX92150.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX92151.1 - 1.5e-72 243.0 4.2 2e-72 242.6 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX92152.1 - 2.2e-10 40.8 1.5 2.5e-10 40.6 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX92152.1 - 0.015 14.1 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family PhoLip_ATPase_C PF16212.5 EAX92153.1 - 1.8e-55 188.4 32.0 1.8e-55 188.4 32.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAX92153.1 - 1.6e-21 75.8 2.4 1.6e-21 75.8 2.4 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAX92153.1 - 5.7e-13 49.6 0.1 2.1e-07 31.5 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAX92153.1 - 1.6e-12 47.3 0.0 4.5e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EAX92153.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAX92153.1 - 0.0002 21.2 0.4 0.0014 18.5 0.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 EAX92154.1 - 2.7e-53 180.9 0.0 4.6e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX92154.1 - 6.8e-50 169.9 0.0 2.2e-49 168.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EAX92154.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family IBD PF10416.9 EAX92155.1 - 1.6e-44 151.0 0.6 2e-44 150.7 0.6 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF2089 PF09862.9 EAX92155.1 - 0.062 13.3 0.1 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) 14-3-3 PF00244.20 EAX92156.1 - 5.3e-52 176.5 6.5 5.3e-52 176.5 6.5 1.8 2 0 0 2 2 2 1 14-3-3 protein Neur_chan_memb PF02932.16 EAX92156.1 - 0.16 12.0 7.8 0.32 11.0 7.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EAX92156.1 - 7.3 4.8 17.6 11 4.1 17.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_15 PF00723.21 EAX92158.1 - 7.1e-06 25.1 0.1 2.9e-05 23.0 0.1 2.0 2 1 1 3 3 3 2 Glycosyl hydrolases family 15 Myb_DNA-binding PF00249.31 EAX92159.1 - 1.1e-05 25.5 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_1 PF00036.32 EAX92160.1 - 9.7e-20 68.6 9.5 2.1e-06 26.9 0.4 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EAX92160.1 - 2.3e-18 64.5 2.3 0.00014 21.5 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EAX92160.1 - 1e-15 57.9 8.9 9.8e-13 48.4 1.8 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX92160.1 - 2.1e-13 49.1 9.3 0.0001 21.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EAX92160.1 - 2.2e-11 43.4 13.1 0.00025 20.8 0.4 4.4 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EAX92160.1 - 0.001 19.3 0.4 0.17 12.3 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain Pneumo_matrix PF03393.16 EAX92160.1 - 0.089 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein Snf7 PF03357.21 EAX92160.1 - 0.098 12.3 1.6 0.16 11.6 1.6 1.3 1 0 0 1 1 1 0 Snf7 Shisa PF13908.6 EAX92161.1 - 0.00022 21.5 4.4 0.00022 21.5 4.4 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 EAX92161.1 - 0.0079 15.9 0.3 0.0079 15.9 0.3 1.9 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis TMEM52 PF14979.6 EAX92161.1 - 0.047 13.6 1.9 0.089 12.7 1.9 1.5 1 0 0 1 1 1 0 Transmembrane 52 EphA2_TM PF14575.6 EAX92161.1 - 0.21 12.5 1.4 0.44 11.5 1.3 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2633 PF11119.8 EAX92161.1 - 0.4 10.6 1.4 3.8 7.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Ras PF00071.22 EAX92162.1 - 4.8e-65 218.1 0.1 5.8e-65 217.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92162.1 - 2.5e-36 124.5 0.1 3.5e-36 124.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92162.1 - 2.5e-18 66.1 0.1 3.2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX92162.1 - 1.3e-05 25.2 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX92162.1 - 1.3e-05 25.1 0.3 0.16 11.9 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX92162.1 - 4.3e-05 23.0 0.1 4.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX92162.1 - 6.1e-05 22.6 0.1 0.00039 20.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EAX92162.1 - 0.0007 20.0 0.0 0.048 14.1 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EAX92162.1 - 0.0038 16.7 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX92162.1 - 0.013 15.8 0.0 0.023 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EAX92162.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 EAX92162.1 - 0.022 14.9 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAX92162.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EAX92162.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAX92162.1 - 0.071 13.6 0.2 0.1 13.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EAX92162.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EAX92162.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 EAX92162.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EAX92162.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GDP_Man_Dehyd PF16363.5 EAX92163.1 - 1.5e-05 24.6 0.0 1.6e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAX92163.1 - 0.00013 21.5 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAX92163.1 - 0.0021 17.3 0.0 0.0025 17.1 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EAX92163.1 - 0.0038 16.3 0.0 0.0041 16.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EAX92163.1 - 0.014 14.5 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EAX92163.1 - 0.14 12.1 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 KR domain Bmt2 PF11968.8 EAX92164.1 - 0.078 12.8 0.3 5.1 6.9 0.1 2.1 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF4107 PF13389.6 EAX92167.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PapD_N PF00345.20 EAX92169.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Trypan_PARP PF05887.11 EAX92170.1 - 0.18 11.7 10.0 0.21 11.6 10.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX92170.1 - 4.2 7.8 5.6 4.6 7.7 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX92171.1 - 0.12 12.8 1.6 0.16 12.4 1.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TPR_MLP1_2 PF07926.12 EAX92173.1 - 3.2e-05 24.0 2.2 3.2e-05 24.0 2.2 2.6 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 EAX92173.1 - 0.0029 17.8 4.8 0.0029 17.8 4.8 2.6 1 1 1 2 2 2 1 Homeobox associated leucine zipper Ribosomal_L29 PF00831.23 EAX92173.1 - 0.0081 16.1 8.5 0.74 9.8 2.1 2.8 2 1 0 2 2 2 2 Ribosomal L29 protein Fungal_TACC PF12709.7 EAX92173.1 - 0.017 15.5 16.2 0.75 10.3 3.0 3.2 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins GTP-bdg_M PF16360.5 EAX92173.1 - 0.018 15.7 5.1 2.6 8.7 0.3 2.9 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region ACR_tran PF00873.19 EAX92173.1 - 0.027 12.2 3.4 0.031 12.0 3.4 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FlxA PF14282.6 EAX92173.1 - 0.029 14.4 17.5 0.12 12.4 5.0 2.2 1 1 1 2 2 2 0 FlxA-like protein Swi5 PF07061.11 EAX92173.1 - 0.036 14.1 13.1 0.47 10.6 4.2 2.7 2 1 1 3 3 2 0 Swi5 DUF724 PF05266.14 EAX92173.1 - 0.054 13.3 10.9 0.079 12.8 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF489 PF04356.12 EAX92173.1 - 0.064 13.3 4.7 0.054 13.5 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Rho_Binding PF08912.11 EAX92173.1 - 0.064 14.1 7.7 0.064 14.1 7.7 3.3 1 1 2 3 3 3 0 Rho Binding APG6_N PF17675.1 EAX92173.1 - 0.073 13.6 19.9 1.1 9.8 19.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2459 PF09601.10 EAX92173.1 - 0.12 12.1 0.9 0.23 11.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) FlaC_arch PF05377.11 EAX92173.1 - 0.13 12.7 11.7 1.9 8.9 1.8 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tho2 PF11262.8 EAX92173.1 - 0.15 11.3 13.6 0.49 9.6 11.4 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Allexi_40kDa PF05549.11 EAX92173.1 - 0.15 11.5 6.6 0.16 11.5 5.6 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein DivIC PF04977.15 EAX92173.1 - 0.17 11.7 17.0 2 8.2 4.0 2.7 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.12 EAX92173.1 - 0.18 11.9 3.2 0.59 10.2 2.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEPcase PF00311.17 EAX92173.1 - 0.2 9.7 8.4 0.24 9.5 8.4 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase JAKMIP_CC3 PF16034.5 EAX92173.1 - 0.24 11.3 13.7 0.65 9.9 7.9 2.2 1 1 1 2 2 2 0 JAKMIP CC3 domain STAT_alpha PF01017.20 EAX92173.1 - 0.25 11.2 12.1 0.043 13.7 7.0 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain TMCO5 PF14992.6 EAX92173.1 - 0.26 10.8 14.7 0.39 10.3 14.2 1.5 1 1 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 EAX92173.1 - 0.41 10.7 7.1 4.7 7.3 7.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 EAX92173.1 - 0.52 10.0 6.3 1.4 8.7 1.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DASH_Hsk3 PF08227.11 EAX92173.1 - 0.61 10.5 3.4 4.2 7.8 0.6 2.7 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Syntaxin-6_N PF09177.11 EAX92173.1 - 0.69 10.5 9.9 0.23 12.0 4.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 EAX92173.1 - 1.1 7.7 16.2 1.7 7.1 16.2 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A HAUS6_N PF14661.6 EAX92173.1 - 1.2 8.7 15.9 0.43 10.1 6.5 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PI_PP_I PF18363.1 EAX92173.1 - 1.2 9.4 5.0 1.6 8.9 1.2 2.3 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain SlyX PF04102.12 EAX92173.1 - 1.3 9.7 7.0 10 6.8 0.6 2.7 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 EAX92173.1 - 1.3 8.3 11.0 2.2 7.6 11.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 EAX92173.1 - 1.6 8.7 15.3 2.4 8.1 4.3 3.0 1 1 1 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 EAX92173.1 - 1.6 8.9 12.7 2.7 8.2 12.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 EAX92173.1 - 1.8 9.8 11.9 1.4 10.1 8.8 2.4 1 1 2 3 3 3 0 Protein SOGA HIP1_clath_bdg PF16515.5 EAX92173.1 - 1.9 9.2 15.3 3.2 8.4 12.0 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 EAX92173.1 - 2 7.9 11.0 2.5 7.6 11.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 EAX92173.1 - 2.2 8.8 11.1 6 7.4 2.4 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) KMP11 PF03037.16 EAX92173.1 - 3 8.7 8.6 4.4 8.2 6.3 2.2 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 ZapB PF06005.12 EAX92173.1 - 3.4 8.2 16.9 3.2 8.3 3.2 3.2 1 1 2 3 3 3 0 Cell division protein ZapB Uso1_p115_C PF04871.13 EAX92173.1 - 4.3 7.7 18.5 2.3 8.6 15.9 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Viral_P18 PF04521.13 EAX92173.1 - 4.4 7.1 7.1 3.6 7.4 1.0 2.4 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2203 PF09969.9 EAX92173.1 - 4.7 7.9 8.5 4.7 8.0 6.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 EAX92173.1 - 5.1 7.0 18.9 2.2 8.2 2.0 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Atg14 PF10186.9 EAX92173.1 - 5.2 6.0 18.5 2.1 7.4 14.3 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4446 PF14584.6 EAX92173.1 - 7.4 6.5 11.2 3.1 7.8 4.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Spc24 PF08286.11 EAX92173.1 - 7.8 6.8 16.1 4.4 7.6 2.4 2.9 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Yip1 PF04893.17 EAX92175.1 - 0.42 10.3 14.9 0.029 14.1 9.8 1.6 2 0 0 2 2 2 0 Yip1 domain Phage_holin_3_6 PF07332.11 EAX92175.1 - 0.68 10.0 12.1 0.092 12.8 4.0 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SIP1 PF04938.12 EAX92176.1 - 6.7e-06 26.0 1.5 4.4e-05 23.3 1.5 1.9 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Suf PF05843.14 EAX92176.1 - 0.074 13.0 0.1 0.074 13.0 0.1 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-MIZ PF02891.20 EAX92180.1 - 2.2e-06 27.3 1.9 2.2e-06 27.3 0.7 1.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zinc_ribbon_10 PF10058.9 EAX92180.1 - 0.15 11.8 0.2 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Pex14_N PF04695.13 EAX92180.1 - 3 8.5 16.4 0.75 10.4 10.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GGDEF PF00990.21 EAX92181.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain RtcB PF01139.17 EAX92183.1 - 1.3e-148 495.6 0.3 1.5e-148 495.4 0.3 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF917 PF06032.12 EAX92183.1 - 0.029 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Peptidase_M24 PF00557.24 EAX92184.1 - 2.9e-52 177.4 0.1 4e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAX92184.1 - 2.2e-22 79.1 0.0 3.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PheRS_DBD2 PF18554.1 EAX92184.1 - 1 9.4 3.0 2.4 8.2 1.6 2.3 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Ank_2 PF12796.7 EAX92185.1 - 1.9e-125 409.7 84.5 3.8e-14 53.0 0.5 11.3 2 1 13 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92185.1 - 1e-108 354.4 21.5 3.8e-10 40.1 0.0 17.9 3 1 15 18 18 18 16 Ankyrin repeats (many copies) Ank PF00023.30 EAX92185.1 - 2.2e-95 309.3 13.2 8e-06 26.1 0.0 16.6 17 0 0 17 17 17 16 Ankyrin repeat Ank_5 PF13857.6 EAX92185.1 - 1.3e-57 191.1 9.7 7.5e-08 32.5 0.0 10.9 3 1 13 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92185.1 - 7.7e-54 173.4 21.8 0.00011 22.4 0.0 18.5 19 0 0 19 19 19 15 Ankyrin repeat DUF3447 PF11929.8 EAX92185.1 - 8.3e-36 121.8 4.6 8.3e-36 121.8 4.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) DUF5475 PF17569.2 EAX92185.1 - 1.1e-05 25.7 16.9 2.2e+02 2.3 0.0 11.4 2 1 10 12 12 12 0 Family of unknown function (DUF5475) DUF3124 PF11322.8 EAX92185.1 - 0.053 13.7 4.9 42 4.4 0.0 5.3 1 1 8 9 9 9 0 Protein of unknown function (DUF3124) DUF348 PF03990.14 EAX92185.1 - 0.43 10.4 31.1 3.3e+02 1.1 0.0 13.1 15 0 0 15 15 15 0 G5-linked-Ubiquitin-like domain DUF1103 PF06513.11 EAX92185.1 - 3.5 7.2 42.3 3.3 7.3 9.4 3.2 1 1 2 3 3 3 0 Repeat of unknown function (DUF1103) PTCB-BRCT PF12738.7 EAX92188.1 - 6.6e-23 80.4 2.5 4.7e-13 48.9 0.2 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EAX92188.1 - 1.4e-19 70.2 5.9 6.3e-06 26.5 0.1 6.0 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAX92188.1 - 1.2e-07 32.1 3.8 0.17 12.3 0.0 5.0 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain DUF5365 PF17326.2 EAX92189.1 - 0.014 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Shisa PF13908.6 EAX92190.1 - 0.013 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EAX92190.1 - 0.088 13.7 0.1 0.18 12.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DDE_1 PF03184.19 EAX92191.1 - 2.9e-15 56.4 0.0 4.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RICH PF05062.12 EAX92192.1 - 0.019 15.3 2.5 0.019 15.3 2.5 5.3 4 1 3 7 7 7 0 RICH domain Gp-FAR-1 PF05823.12 EAX92192.1 - 0.61 10.4 30.8 0.13 12.7 3.2 3.6 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Not3 PF04065.15 EAX92192.1 - 0.81 9.1 54.8 1.5 8.2 14.8 4.1 1 1 3 4 4 4 0 Not1 N-terminal domain, CCR4-Not complex component Fez1 PF06818.15 EAX92192.1 - 4.1 7.8 60.7 5.5 7.4 25.1 3.5 1 1 2 3 3 3 0 Fez1 Zw10 PF06248.13 EAX92192.1 - 4.1 5.9 37.2 4.4 5.7 21.8 2.9 2 1 0 2 2 2 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 EAX92192.1 - 7.7 5.3 67.3 0.99 8.2 22.7 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAX92192.1 - 8 5.7 55.2 2.3 7.5 15.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Piezo_RRas_bdg PF12166.8 EAX92194.1 - 6.3e-12 45.5 4.2 6.3e-12 45.5 4.2 2.6 3 0 0 3 3 3 1 Piezo non-specific cation channel, R-Ras-binding domain TAP42 PF04177.12 EAX92194.1 - 0.0098 15.0 2.0 0.015 14.4 2.0 1.2 1 0 0 1 1 1 1 TAP42-like family NUMOD4 PF07463.11 EAX92194.1 - 0.027 14.7 0.1 0.71 10.1 0.5 2.7 2 0 0 2 2 2 0 NUMOD4 motif CPSF100_C PF13299.6 EAX92194.1 - 0.19 11.9 4.4 0.36 11.0 4.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 EAX92194.1 - 7.6 5.8 6.4 12 5.2 6.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT KilA-N PF04383.13 EAX92195.1 - 1.8e-22 79.3 0.2 2.5e-22 78.8 0.2 1.3 1 0 0 1 1 1 1 KilA-N domain Pox_A32 PF04665.12 EAX92197.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92197.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92197.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92197.1 - 0.00013 22.0 3.1 0.00027 21.0 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92197.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92197.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92197.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92197.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92197.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX92197.1 - 0.088 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX92197.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX92197.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX92198.1 - 0.66 9.9 4.1 1.6 8.7 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Helicase_C PF00271.31 EAX92200.1 - 0.16 12.3 5.7 0.082 13.3 2.5 2.2 2 0 0 2 2 2 0 Helicase conserved C-terminal domain LRR_5 PF13306.6 EAX92201.1 - 2.9e-139 457.3 142.3 2.8e-28 98.4 14.7 9.2 3 3 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92201.1 - 2.2e-20 72.2 4.5 0.0046 16.7 0.0 12.5 9 5 6 15 15 15 5 Leucine rich repeat LRR_4 PF12799.7 EAX92201.1 - 0.048 14.1 20.0 2 9.0 0.0 9.2 7 2 5 12 12 12 0 Leucine Rich repeats (2 copies) DUF3827 PF12877.7 EAX92201.1 - 0.052 11.9 0.5 0.081 11.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) LRR_1 PF00560.33 EAX92201.1 - 0.5 11.1 6.5 7.4 7.5 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat TPR_MLP1_2 PF07926.12 EAX92202.1 - 0.0045 17.0 10.9 0.015 15.3 4.1 2.2 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Zein-binding PF04576.15 EAX92202.1 - 0.0049 17.1 0.7 0.0049 17.1 0.7 2.1 2 1 0 2 2 2 1 Zein-binding Mto2_bdg PF12808.7 EAX92202.1 - 0.0056 17.0 3.4 0.015 15.6 3.4 1.8 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region ACP_PD PF04336.12 EAX92202.1 - 0.015 15.7 1.4 0.024 15.1 0.8 1.6 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Rootletin PF15035.6 EAX92202.1 - 0.019 15.0 6.0 0.024 14.6 6.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2408 PF10303.9 EAX92202.1 - 0.034 14.7 5.5 0.11 13.1 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Het-C PF07217.11 EAX92202.1 - 0.041 12.4 3.3 0.047 12.2 3.3 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CHIP_TPR_N PF18391.1 EAX92202.1 - 0.35 11.7 8.0 0.85 10.4 8.0 1.9 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain FliD_N PF02465.18 EAX92202.1 - 0.49 11.1 4.8 0.14 12.8 0.6 2.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus YabA PF06156.13 EAX92202.1 - 1.1 10.0 11.8 0.45 11.2 2.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF1690 PF07956.11 EAX92202.1 - 3.9 7.9 9.8 4.7 7.6 0.3 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) LMBR1 PF04791.16 EAX92202.1 - 4.4 6.1 5.4 4.7 6.0 5.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Lge1 PF11488.8 EAX92202.1 - 5.1 7.4 10.8 4.7 7.5 4.6 2.9 2 2 0 2 2 2 0 Transcriptional regulatory protein LGE1 FapA PF03961.13 EAX92202.1 - 5.5 5.5 10.8 0.82 8.2 6.5 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A ACCA PF03255.14 EAX92202.1 - 6.1 6.7 7.5 4.3 7.2 4.1 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spt4 PF06093.13 EAX92203.1 - 3.8e-14 52.5 0.9 5.8e-14 51.9 0.9 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger OrfB_Zn_ribbon PF07282.11 EAX92203.1 - 0.021 14.8 0.7 9.6 6.2 0.0 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain COG7 PF10191.9 EAX92203.1 - 0.027 12.8 0.0 0.029 12.6 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) zf-ribbon_3 PF13248.6 EAX92203.1 - 0.055 12.9 1.0 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Myb_DNA-binding PF00249.31 EAX92204.1 - 1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EAX92204.1 - 0.00012 22.4 1.5 0.00024 21.4 0.1 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EAX92204.1 - 0.00047 20.4 0.0 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rop PF01815.16 EAX92204.1 - 1.2 9.0 3.7 8.6 6.3 1.7 2.9 3 0 0 3 3 3 0 Rop protein RRM_1 PF00076.22 EAX92206.1 - 2e-17 62.7 0.0 3.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX92206.1 - 7e-05 22.4 0.0 9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EAX92206.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 RL domain RRM_occluded PF16842.5 EAX92206.1 - 0.038 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAX92206.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EAP30 PF04157.16 EAX92207.1 - 3.6e-55 186.8 0.0 4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Tape_meas_lam_C PF09718.10 EAX92207.1 - 0.0042 17.2 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_Mu_Gam PF07352.12 EAX92207.1 - 0.25 11.2 5.3 0.29 11.0 1.7 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein RRM_1 PF00076.22 EAX92208.1 - 2.9e-13 49.4 0.0 5.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX92208.1 - 0.0048 16.5 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arf PF00025.21 EAX92210.1 - 3.3e-68 228.6 0.0 3.7e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX92210.1 - 9.8e-13 48.4 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX92210.1 - 3.2e-11 43.1 0.0 3.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EAX92210.1 - 1.7e-09 37.3 0.4 1.3e-08 34.5 0.1 1.9 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 EAX92210.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX92210.1 - 3.9e-07 29.7 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX92210.1 - 0.0011 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase USP7_C2 PF14533.6 EAX92211.1 - 9.8e-10 38.5 0.1 2.1e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 EAX92211.1 - 0.0003 20.2 0.1 0.00082 18.7 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 LacI PF00356.21 EAX92211.1 - 0.12 12.1 0.0 0.42 10.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family ApbA_C PF08546.11 EAX92212.1 - 0.15 12.2 2.0 0.42 10.8 0.6 2.5 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF3800 PF12686.7 EAX92212.1 - 0.16 12.6 1.8 25 5.5 1.8 3.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4481 PF14800.6 EAX92212.1 - 0.55 9.6 3.2 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) COMMD1_N PF17221.3 EAX92212.1 - 0.71 10.2 0.0 0.71 10.2 0.0 3.3 3 0 0 3 3 3 0 COMMD1 N-terminal domain YtxH PF12732.7 EAX92212.1 - 2.1 8.9 11.8 11 6.6 2.0 4.8 4 2 0 4 4 4 0 YtxH-like protein DUF1788 PF08747.11 EAX92212.1 - 5.6 7.0 6.3 3.7 7.6 1.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) DUF948 PF06103.11 EAX92212.1 - 6.5 7.1 19.1 10 6.4 4.4 5.7 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) ARA70 PF12489.8 EAX92212.1 - 7.6 6.7 16.1 0.59 10.3 5.9 3.3 2 1 1 3 3 3 0 Nuclear coactivator FliG_N PF14842.6 EAX92212.1 - 8.5 7.0 9.5 18 5.9 0.0 4.4 3 2 0 4 4 4 0 FliG N-terminal domain Vac14_Fig4_bd PF11916.8 EAX92213.1 - 0.0036 17.0 0.3 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding zf-MIZ PF02891.20 EAX92215.1 - 1.1e-16 60.3 0.3 2.2e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAX92215.1 - 0.01 15.6 0.2 0.027 14.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Gly-zipper_Omp PF13488.6 EAX92216.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX92216.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX92216.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX92218.1 - 5.1e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX92218.1 - 0.0051 16.8 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX92218.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 zf-UBR PF02207.20 EAX92219.1 - 1.7e-13 50.5 24.8 1.7e-13 50.5 24.8 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Ras PF00071.22 EAX92221.1 - 2.4e-55 186.6 0.7 2.8e-55 186.3 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92221.1 - 8.8e-35 119.5 0.1 1.3e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92221.1 - 3.7e-16 59.1 0.2 5e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX92221.1 - 9.8e-08 32.1 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX92221.1 - 1.3e-07 31.2 0.5 1.6e-07 31.0 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX92221.1 - 1.9e-07 30.8 0.2 3.2e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX92221.1 - 1.6e-06 27.6 1.1 4e-06 26.4 1.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX92221.1 - 4.8e-06 26.2 0.1 1.1e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAX92221.1 - 3e-05 24.0 1.8 0.032 14.1 0.4 2.3 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAX92221.1 - 0.0004 19.6 3.6 0.03 13.5 1.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Septin PF00735.18 EAX92221.1 - 0.0019 17.6 0.3 0.0034 16.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1_Xtn PF16897.5 EAX92221.1 - 0.0088 16.0 0.9 0.021 14.8 0.9 1.8 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DLIC PF05783.11 EAX92221.1 - 0.02 13.8 0.3 2.4 6.9 0.1 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 EAX92221.1 - 0.038 13.7 0.1 0.29 10.9 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Attractin PF08037.11 EAX92221.1 - 0.09 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Attractin family Ribosomal_L7Ae PF01248.26 EAX92221.1 - 0.14 11.9 0.5 0.36 10.6 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Importin_rep_6 PF18829.1 EAX92222.1 - 0.0081 16.3 2.0 0.0081 16.3 2.0 2.0 1 1 1 2 2 2 1 Importin repeat 6 ASPRs PF17641.2 EAX92222.1 - 0.044 14.1 2.1 0.054 13.8 2.1 1.2 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related RasGAP_C PF03836.15 EAX92222.1 - 0.044 13.9 8.1 0.06 13.5 8.1 1.3 1 1 0 1 1 1 0 RasGAP C-terminus Urease_alpha PF00449.20 EAX92222.1 - 0.052 13.9 0.1 0.07 13.5 0.1 1.1 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain TMP PF05017.14 EAX92223.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DNA_pol_B_2 PF03175.13 EAX92224.1 - 4.4e-16 58.8 1.5 8.5e-16 57.9 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5065 PF16723.5 EAX92224.1 - 0.029 14.4 2.9 0.59 10.2 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5065) JMY PF15871.5 EAX92224.1 - 0.063 12.6 0.3 0.094 12.0 0.3 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PTR PF12789.7 EAX92225.1 - 1.7e-22 79.2 52.6 3.4e-09 36.6 3.6 6.6 6 2 0 6 6 6 4 Phage tail repeat like Collagen PF01391.18 EAX92225.1 - 2.3e-06 27.3 12.3 4.1e-06 26.4 12.3 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX92225.1 - 0.0079 16.3 14.3 0.079 13.1 0.0 3.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus RecG_N PF17190.4 EAX92225.1 - 0.31 11.8 11.4 10 6.9 0.6 5.1 4 1 0 5 5 5 0 RecG N-terminal helical domain EMP24_GP25L PF01105.24 EAX92225.1 - 2.5 8.0 13.3 7.9 6.4 1.8 4.1 3 1 0 3 3 3 0 emp24/gp25L/p24 family/GOLD RraB PF06877.11 EAX92225.1 - 9.4 7.0 6.7 71 4.2 1.1 3.4 2 1 1 3 3 3 0 Regulator of ribonuclease activity B DUF3839 PF12943.7 EAX92226.1 - 1.2e-148 493.1 13.2 1.5e-148 492.8 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92226.1 - 0.029 14.2 0.5 0.087 12.7 0.2 1.8 1 1 1 2 2 2 0 Nucleotidyltransferase APC_u14 PF16635.5 EAX92226.1 - 0.57 10.8 2.9 0.77 10.3 1.3 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX92226.1 - 1.7 9.1 5.7 2.3 8.8 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DNA_pol_B_2 PF03175.13 EAX92227.1 - 5.1e-26 91.6 11.0 3.5e-25 88.8 11.0 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX92227.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF2939 PF11159.8 EAX92230.1 - 0.015 15.6 0.6 0.02 15.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX92230.1 - 2.7 7.0 5.2 2.6 7.0 5.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX92230.1 - 8.5 6.4 8.9 9 6.3 8.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX92231.1 - 0.008 16.2 0.1 0.0094 16.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX92232.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX92233.1 - 0.11 13.0 1.5 0.14 12.6 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Ureide_permease PF07168.11 EAX92235.1 - 0.15 10.8 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Ureide permease Prp18 PF02840.15 EAX92236.1 - 0.0068 16.5 0.0 0.0079 16.2 0.0 1.1 1 0 0 1 1 1 1 Prp18 domain P_proprotein PF01483.20 EAX92237.1 - 3.6e-08 33.3 0.0 8.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain LPD18 PF18832.1 EAX92237.1 - 0.034 14.2 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 Arc_C PF18162.1 EAX92237.1 - 0.17 11.7 0.0 0.55 10.1 0.0 1.8 1 0 0 1 1 1 0 Arc C-lobe DUF4107 PF13389.6 EAX92238.1 - 4.3e-72 241.6 4.4 5.1e-72 241.3 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX92238.1 - 0.11 10.9 0.9 0.15 10.4 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase Pkinase PF00069.25 EAX92242.1 - 1.2e-18 67.4 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 EAX92242.1 - 6.5e-15 55.5 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 EAX92242.1 - 9.7e-08 31.6 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 EAX92242.1 - 0.00035 20.6 0.0 0.00065 19.8 0.0 1.4 1 0 0 1 1 1 1 PH domain APH PF01636.23 EAX92242.1 - 0.037 13.9 0.0 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_11 PF15413.6 EAX92242.1 - 0.1 13.0 0.2 1.4 9.3 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain zf-DBF PF07535.12 EAX92243.1 - 5.3e-05 23.2 4.8 0.00012 22.1 4.8 1.6 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_jaz PF12171.8 EAX92243.1 - 0.1 12.9 1.0 0.23 11.8 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AcetylCoA_hydro PF02550.15 EAX92244.1 - 3.3e-43 148.0 0.0 4.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EAX92244.1 - 4.1e-40 137.2 0.0 6.5e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain HSP70 PF00012.20 EAX92245.1 - 2.6e-49 167.9 0.0 2.6e-49 167.9 0.0 3.2 3 1 0 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 EAX92245.1 - 0.0001 21.3 0.0 0.00022 20.2 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein SIP PF04954.13 EAX92245.1 - 0.11 13.1 0.1 0.6 10.6 0.1 2.3 2 0 0 2 2 2 0 Siderophore-interacting protein Ank_2 PF12796.7 EAX92246.1 - 2.4e-34 117.8 2.0 5.3e-15 55.8 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92246.1 - 3.5e-34 116.7 3.8 4.8e-10 39.8 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92246.1 - 5.8e-31 106.2 0.4 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92246.1 - 2.9e-26 88.6 1.6 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX92246.1 - 1.2e-23 82.5 3.0 0.00026 21.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX92246.1 - 0.0033 17.4 0.7 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) P22_Cro PF14549.6 EAX92247.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Ank_2 PF12796.7 EAX92249.1 - 2e-34 118.0 1.5 2e-13 50.7 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92249.1 - 3.8e-34 116.6 3.6 4.8e-10 39.8 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92249.1 - 5.9e-31 106.1 0.3 3.5e-07 30.3 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92249.1 - 1.9e-26 89.2 1.2 6e-05 23.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX92249.1 - 8.1e-24 83.0 2.6 0.00026 21.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX92249.1 - 0.0035 17.3 0.7 1.6 8.7 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DUF5623 PF18536.1 EAX92250.1 - 0.019 15.2 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX92250.1 - 0.43 10.5 8.0 0.15 12.0 2.9 2.2 2 0 0 2 2 2 0 Spo12 family PI3_PI4_kinase PF00454.27 EAX92251.1 - 1.2e-43 149.7 0.1 1.1e-42 146.6 0.0 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAX92251.1 - 1.3e-14 54.2 11.8 1e-13 51.3 5.2 3.1 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 EAX92251.1 - 1.9e-09 37.2 0.0 6.7e-09 35.4 0.0 2.1 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EAX92251.1 - 3.5e-09 36.8 21.6 4.1e-09 36.5 0.6 4.9 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) ANAPC3 PF12895.7 EAX92251.1 - 0.0019 18.4 6.8 0.074 13.3 0.5 4.1 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DDE_Tnp_ISL3 PF01610.17 EAX92251.1 - 0.029 14.1 0.9 0.088 12.5 0.9 1.8 1 0 0 1 1 1 0 Transposase TPR_19 PF14559.6 EAX92251.1 - 0.078 13.5 0.9 59 4.3 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF370 PF04025.12 EAX92251.1 - 0.079 13.1 0.2 0.36 11.0 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Coatomer_WDAD PF04053.14 EAX92252.1 - 0.0025 16.9 0.2 0.0065 15.6 0.2 1.6 1 1 0 1 1 1 1 Coatomer WD associated region LPD13 PF18825.1 EAX92252.1 - 0.16 11.7 1.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 DUF2733 PF10813.8 EAX92252.1 - 0.2 11.4 0.1 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) UQ_con PF00179.26 EAX92253.1 - 9.8e-43 145.2 0.4 1.1e-42 145.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EAX92253.1 - 0.00045 19.9 0.1 0.00067 19.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EAX92253.1 - 0.0065 16.8 0.1 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 RWD domain LRR_5 PF13306.6 EAX92254.1 - 1.1e-111 368.1 60.1 6e-27 94.1 4.3 7.3 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92254.1 - 1.6e-24 85.5 0.4 0.00013 21.7 0.2 9.6 6 3 3 9 9 9 6 Leucine rich repeat DAN PF03045.15 EAX92254.1 - 7.5 6.6 7.4 2.5 8.2 0.1 3.5 4 0 0 4 4 4 0 DAN domain DUF4107 PF13389.6 EAX92255.1 - 2.4e-72 242.4 3.0 3.2e-72 242.0 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX92256.1 - 0.0035 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX92257.1 - 3.2e-155 514.6 12.9 4.1e-155 514.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX92257.1 - 4.5 7.8 7.5 1.9 9.0 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX92258.1 - 4.5e-07 30.4 0.3 9e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Fe-ADH PF00465.19 EAX92260.1 - 2.5e-56 191.1 0.0 2.8e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX92260.1 - 2.5e-08 34.0 0.0 1.1e-06 28.6 0.0 2.4 2 1 1 3 3 3 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EAX92260.1 - 0.04 13.1 0.0 9 5.4 0.0 2.5 3 0 0 3 3 3 0 3-dehydroquinate synthase MULE PF10551.9 EAX92261.1 - 1.9e-13 50.6 0.4 1.9e-13 50.6 0.4 2.4 3 0 0 3 3 3 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX92261.1 - 0.007 16.1 0.3 0.026 14.3 0.2 1.9 1 1 1 2 2 2 1 Transposase DUF2960 PF11173.8 EAX92261.1 - 0.051 14.0 0.3 0.2 12.1 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Transposase_mut PF00872.18 EAX92261.1 - 0.24 10.2 2.9 0.82 8.4 2.9 1.8 1 1 0 1 1 1 0 Transposase, Mutator family Pox_A9 PF04835.12 EAX92262.1 - 1.3e-05 25.2 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 A9 protein conserved region ASFV_J13L PF05568.11 EAX92262.1 - 0.00077 19.3 0.5 0.00095 19.0 0.5 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein CD34_antigen PF06365.12 EAX92262.1 - 0.16 11.5 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PDEase_I PF00233.19 EAX92263.1 - 6.3e-43 147.2 0.1 7.1e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Spot_14 PF07084.12 EAX92263.1 - 0.069 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF4106 PF13388.6 EAX92265.1 - 5.2e-271 898.9 19.2 5.2e-271 898.9 19.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX92265.1 - 0.096 13.0 2.6 1.3 9.4 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated CHASE3 PF05227.13 EAX92267.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX92267.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) Ank_2 PF12796.7 EAX92268.1 - 1.6e-255 826.6 84.8 4.5e-21 75.2 1.1 18.2 1 1 17 19 19 19 19 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92268.1 - 2e-196 634.1 56.8 2e-11 44.2 0.0 26.8 5 2 22 29 29 29 29 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92268.1 - 1.2e-176 550.7 70.5 3.4e-05 23.9 0.1 35.7 36 0 0 36 36 36 34 Ankyrin repeat Ank PF00023.30 EAX92268.1 - 1.9e-174 559.3 78.5 3.8e-06 27.1 0.0 35.7 36 0 0 36 36 36 34 Ankyrin repeat Ank_5 PF13857.6 EAX92268.1 - 3.4e-161 521.2 57.4 3.9e-10 39.8 0.0 29.4 5 5 25 32 32 32 31 Ankyrin repeats (many copies) YfmQ PF10787.9 EAX92268.1 - 5.9e-08 32.6 3.9 1.3 8.7 0.3 10.1 7 3 5 13 13 13 1 Uncharacterised protein from bacillus cereus group Imm_superinfect PF14373.6 EAX92268.1 - 5.3e-07 29.5 0.0 1.3e+02 2.6 0.0 10.6 15 0 0 15 15 15 0 Superinfection immunity protein PolyA_pol_RNAbd PF12627.7 EAX92268.1 - 0.0014 18.4 0.0 3.5 7.5 0.0 4.1 3 0 0 3 3 3 1 Probable RNA and SrmB- binding site of polymerase A HP0268 PF18618.1 EAX92268.1 - 0.011 16.1 0.2 59 4.2 0.0 5.1 4 0 0 4 4 4 0 HP0268 DUF5049 PF16468.5 EAX92268.1 - 0.034 14.0 6.0 20 5.2 0.0 6.6 7 1 0 7 7 6 0 Domain of unknown function (DUF5049) Rhomboid_N PF12122.8 EAX92268.1 - 0.069 13.3 3.8 4.4e+02 1.1 0.0 7.9 12 0 0 12 12 12 0 Cytoplasmic N-terminal domain of rhomboid serine protease APOBEC4 PF18775.1 EAX92268.1 - 0.1 12.7 18.9 16 5.8 0.1 9.4 12 0 0 12 12 12 0 APOBEC4 DCB PF16213.5 EAX92268.1 - 0.2 11.3 11.3 16 5.1 0.1 8.6 7 5 5 13 13 13 0 Dimerisation and cyclophilin-binding domain of Mon2 CDKN3 PF05706.12 EAX92268.1 - 0.21 11.2 4.0 19 4.9 0.0 5.5 7 1 0 7 7 7 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Integrin_b_cyt PF08725.11 EAX92268.1 - 0.27 11.0 1.3 21 4.9 0.0 4.6 5 0 0 5 5 5 0 Integrin beta cytoplasmic domain DUF4792 PF16040.5 EAX92268.1 - 4.1 7.4 5.5 42 4.1 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4792) LRR_5 PF13306.6 EAX92269.1 - 2.9e-96 318.2 54.5 2.3e-30 105.2 12.1 6.0 1 1 5 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92269.1 - 3e-22 78.1 3.3 0.0019 17.9 0.0 9.0 4 2 7 11 11 11 10 Leucine rich repeat DUF676 PF05057.14 EAX92269.1 - 0.11 12.0 1.4 11 5.5 0.1 2.6 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Acetyltransf_19 PF18015.1 EAX92269.1 - 0.53 10.5 4.5 1.3 9.3 0.6 3.3 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain LRR_4 PF12799.7 EAX92269.1 - 4.3 7.9 24.7 2.2 8.8 0.0 8.3 6 4 1 9 9 9 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX92270.1 - 1.6e-48 163.9 19.9 5.5e-32 110.4 5.6 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92270.1 - 9e-15 54.2 0.1 0.00063 19.4 0.0 4.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EAX92270.1 - 0.01 16.2 8.4 0.028 14.8 0.4 4.2 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAX92270.1 - 0.43 10.8 6.7 5.8 7.2 0.1 3.8 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) FNIP PF05725.12 EAX92270.1 - 0.59 10.3 7.3 1.7 8.9 1.4 4.1 3 2 0 3 3 3 0 FNIP Repeat DEFB136 PF17333.2 EAX92270.1 - 2 8.4 5.0 26 4.9 0.0 3.7 5 0 0 5 5 5 0 Beta defensin 136 LRR_5 PF13306.6 EAX92271.1 - 4.5e-27 94.5 14.6 4.5e-27 94.5 14.6 2.5 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92271.1 - 1.6e-10 40.6 0.5 0.0033 17.2 0.0 4.3 2 1 2 4 4 4 3 Leucine rich repeat Rax2 PF12768.7 EAX92271.1 - 0.0013 18.3 3.9 0.0024 17.3 3.9 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity VSP PF03302.13 EAX92271.1 - 0.0059 15.5 0.4 0.0099 14.8 0.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4448 PF14610.6 EAX92271.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 EAX92271.1 - 0.018 15.3 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF2700 PF10912.8 EAX92271.1 - 0.026 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) TMEM154 PF15102.6 EAX92271.1 - 0.03 14.2 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 EAX92271.1 - 0.1 12.5 5.9 0.16 11.8 5.9 1.5 1 1 0 1 1 1 0 Rifin SKG6 PF08693.10 EAX92271.1 - 0.33 10.4 8.0 0.55 9.7 8.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EAX92271.1 - 0.4 10.5 8.1 0.66 9.8 8.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EAX92271.1 - 0.4 11.6 1.5 0.82 10.6 1.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.6 EAX92272.1 - 0.0046 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX92272.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX92272.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX92272.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX92272.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Tho2 PF11262.8 EAX92274.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX92274.1 - 0.079 13.6 0.9 0.13 13.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX92274.1 - 0.38 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family KilA-N PF04383.13 EAX92275.1 - 3e-06 27.0 4.0 1.2e-05 25.1 0.4 2.9 2 1 0 2 2 2 1 KilA-N domain MULE PF10551.9 EAX92277.1 - 8.7e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAX92277.1 - 0.054 14.2 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Metallophos PF00149.28 EAX92278.1 - 7.1e-18 65.8 0.0 1.4e-17 64.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX92278.1 - 0.00015 22.0 0.0 0.0009 19.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sigma_reg_N PF13800.6 EAX92278.1 - 8.9 6.7 10.2 14 6.1 1.2 3.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PH PF00169.29 EAX92279.1 - 1.4e-12 48.0 0.2 1.8e-12 47.7 0.2 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EAX92279.1 - 2.2e-09 37.7 4.0 1.7e-07 31.6 4.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EAX92279.1 - 7.3e-06 26.0 0.1 8.4e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EAX92279.1 - 0.00016 21.9 0.0 0.00019 21.6 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain EspG PF06872.11 EAX92279.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 EspG protein EF-hand_7 PF13499.6 EAX92280.1 - 1e-06 29.1 0.1 0.0004 20.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX92280.1 - 1.1e-06 28.1 0.3 0.0033 17.2 0.1 3.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EAX92280.1 - 1.4e-05 24.3 2.2 0.0047 16.4 0.1 4.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 EAX92280.1 - 0.0062 16.4 2.3 0.45 10.4 0.6 3.2 2 1 1 4 4 4 1 EF-hand domain pair EspA PF03433.13 EAX92280.1 - 0.055 13.3 0.0 0.095 12.5 0.0 1.4 1 1 0 1 1 1 0 EspA-like secreted protein DUF2624 PF11116.8 EAX92280.1 - 0.1 13.5 0.0 0.77 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Adeno_terminal PF02459.15 EAX92280.1 - 0.11 10.9 0.3 2 6.7 0.1 2.0 1 1 1 2 2 2 0 Adenoviral DNA terminal protein Goodbye PF17109.5 EAX92280.1 - 0.12 12.9 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Ribosomal_L14e PF01929.17 EAX92281.1 - 3e-18 66.1 1.9 4.3e-18 65.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Ank_4 PF13637.6 EAX92282.1 - 1.8e-56 187.8 5.1 6.3e-13 49.0 0.0 7.7 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92282.1 - 3e-54 181.6 19.1 4.8e-17 62.3 0.5 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92282.1 - 1.6e-52 173.8 4.8 1.2e-08 35.0 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX92282.1 - 1.8e-40 132.3 11.2 2.9e-05 24.1 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX92282.1 - 1.1e-37 127.6 0.9 3.8e-10 39.8 0.0 5.8 4 1 0 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92282.1 - 1e-36 124.7 6.3 1e-36 124.7 6.3 3.9 3 1 0 3 3 2 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX92282.1 - 7.5e-07 29.3 1.0 20 5.6 0.0 5.4 1 1 4 5 5 5 0 Pleckstrin homology domain MetallophosN PF16371.5 EAX92282.1 - 4e-05 23.8 0.1 0.21 11.9 0.0 3.4 2 1 1 3 3 2 2 N terminal of Calcineurin-like phosphoesterase ThiS-like PF14453.6 EAX92282.1 - 0.00038 20.5 3.3 5.6 7.1 0.0 5.7 3 2 2 5 5 5 1 ThiS-like ubiquitin CEP44 PF15007.6 EAX92282.1 - 0.0015 18.7 0.0 12 6.1 0.0 4.8 1 1 4 5 5 5 1 Centrosomal spindle body, CEP44 PGM_PMM_I PF02878.16 EAX92282.1 - 0.024 14.3 0.1 7.8 6.2 0.0 3.2 2 1 1 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF281 PF03436.13 EAX92282.1 - 0.053 13.9 1.0 33 5.0 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF281) Ribosomal_S6 PF01250.17 EAX92282.1 - 0.057 13.7 0.1 52 4.2 0.0 4.1 1 1 3 5 5 5 0 Ribosomal protein S6 RL PF17797.1 EAX92282.1 - 1.1 9.2 5.1 2.6 8.0 0.4 3.3 3 0 0 3 3 3 0 RL domain V-ATPase_H_N PF03224.14 EAX92283.1 - 5e-44 150.9 2.1 9.7e-44 149.9 2.1 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EAX92283.1 - 1.6e-32 112.1 0.9 1.6e-32 112.1 0.9 2.4 4 0 0 4 4 4 1 V-ATPase subunit H Arm PF00514.23 EAX92283.1 - 0.048 13.7 2.7 1.7 8.8 0.1 4.0 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Ndc80_HEC PF03801.13 EAX92283.1 - 0.11 12.2 0.1 0.47 10.1 0.0 2.1 2 1 0 2 2 2 0 HEC/Ndc80p family MULE PF10551.9 EAX92284.1 - 2.7e-13 50.2 0.2 4.9e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX92284.1 - 0.065 12.9 0.8 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX92284.1 - 0.5 10.6 5.6 1.1 9.6 5.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX92284.1 - 1.5 8.6 5.7 2.3 8.0 5.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mito_fiss_reg PF05308.11 EAX92285.1 - 0.11 12.6 0.4 0.11 12.6 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator TMP PF05017.14 EAX92286.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX92287.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Arena_nucleocap PF00843.17 EAX92288.1 - 0.037 12.9 2.0 0.047 12.6 2.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain PH_18 PF18469.1 EAX92289.1 - 0.073 13.1 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Alpha-amylase PF00128.24 EAX92290.1 - 7.7e-11 42.1 0.0 5.2e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain B12-binding PF02310.19 EAX92290.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain Malic_M PF03949.15 EAX92290.1 - 0.43 9.8 0.8 1.1 8.5 0.3 1.8 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF3446 PF11928.8 EAX92291.1 - 0.016 15.5 0.2 0.03 14.6 0.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Ecm33 PF12454.8 EAX92291.1 - 0.024 14.8 0.7 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein LapA_dom PF06305.11 EAX92291.1 - 0.083 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_5_1 PF06946.11 EAX92291.1 - 0.095 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 DUF2613 PF11021.8 EAX92291.1 - 0.13 12.4 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Syndecan PF01034.20 EAX92292.1 - 0.0023 17.8 0.1 0.0043 16.9 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.12 EAX92292.1 - 0.013 15.3 0.1 0.041 13.7 0.1 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor S1FA PF04689.13 EAX92292.1 - 0.024 14.8 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA SKG6 PF08693.10 EAX92292.1 - 0.025 14.0 0.3 0.038 13.4 0.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 EAX92292.1 - 0.026 14.7 0.0 0.026 14.7 0.0 2.6 2 1 0 2 2 1 0 Glycophorin A FAM163 PF15069.6 EAX92292.1 - 0.039 14.4 0.7 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 FAM163 family Insulin_TMD PF17870.1 EAX92292.1 - 0.063 13.4 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PTP_tm PF18861.1 EAX92292.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 EAX92292.1 - 0.069 12.9 0.7 0.12 12.2 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECSCR PF15820.5 EAX92292.1 - 0.081 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SRTM1 PF15872.5 EAX92292.1 - 0.099 12.8 0.5 0.29 11.3 0.3 2.0 1 1 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 GRA6 PF05084.13 EAX92292.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Chlam_PMP PF02415.17 EAX92293.1 - 1.3e-06 28.5 2.8 0.43 11.2 0.7 4.3 4 0 0 4 4 4 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat EnY2 PF10163.9 EAX92294.1 - 0.0042 17.4 1.8 1.3 9.4 0.1 3.3 1 1 2 3 3 3 1 Transcription factor e(y)2 MinE PF03776.14 EAX92294.1 - 0.081 12.9 3.5 0.63 10.1 0.2 2.9 1 1 2 3 3 3 0 Septum formation topological specificity factor MinE Dsl1_C PF11989.8 EAX92294.1 - 0.12 12.1 4.8 0.088 12.5 2.6 1.6 1 1 1 2 2 2 0 Retrograde transport protein Dsl1 C terminal HTH_9 PF08221.11 EAX92294.1 - 0.32 11.1 12.8 4.7 7.4 0.7 3.6 3 1 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Ofd1_CTDD PF10637.9 EAX92294.1 - 0.47 9.7 3.0 0.48 9.7 1.2 1.7 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term CBF PF03914.17 EAX92294.1 - 5.3 7.1 7.1 11 6.1 7.1 1.7 1 1 0 1 1 1 0 CBF/Mak21 family pP_pnuc_2 PF18166.1 EAX92294.1 - 7 6.7 9.8 2.1 8.4 1.9 2.4 1 1 0 2 2 2 0 Predicted pPIWI-associating nuclease NCD2 PF04905.13 EAX92295.1 - 0.013 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) MtrG PF04210.13 EAX92297.1 - 0.0005 19.9 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4106 PF13388.6 EAX92298.1 - 7.9e-241 799.5 18.7 7.9e-241 799.5 18.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX92298.1 - 0.0028 17.9 1.4 0.057 13.7 0.3 2.9 3 0 0 3 3 3 1 Kidney androgen-regulated RRM_1 PF00076.22 EAX92299.1 - 9.1e-20 70.3 10.0 1.5e-06 27.9 0.2 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAX92299.1 - 3.4e-08 33.4 2.3 0.0083 16.2 0.1 3.9 4 0 0 4 4 4 3 RNA binding motif DUF4523 PF15023.6 EAX92299.1 - 0.0047 16.8 1.9 1.5 8.6 0.1 3.4 3 2 0 3 3 3 2 Protein of unknown function (DUF4523) P2 PF07194.11 EAX92299.1 - 3 8.0 5.4 3.6 7.7 0.4 3.2 3 0 0 3 3 3 0 P2 response regulator binding domain Motile_Sperm PF00635.26 EAX92300.1 - 0.00013 21.8 1.7 0.00013 21.8 1.7 3.2 4 1 0 4 4 4 1 MSP (Major sperm protein) domain ASH PF15780.5 EAX92300.1 - 0.00013 22.1 3.2 0.13 12.5 0.1 5.1 6 0 0 6 6 6 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TLD PF07534.16 EAX92301.1 - 9.3e-30 103.7 0.1 1.3e-29 103.2 0.1 1.2 1 0 0 1 1 1 1 TLD LysM PF01476.20 EAX92301.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 LysM domain NepR PF18557.1 EAX92301.1 - 0.51 10.0 1.7 1.1 9.0 1.7 1.5 1 0 0 1 1 1 0 Anti-sigma factor NepR Rhodanese PF00581.20 EAX92302.1 - 5.8e-13 49.3 0.0 6.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Sod_Fe_C PF02777.18 EAX92303.1 - 1.8e-34 118.0 1.6 1.8e-34 118.0 1.6 1.9 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAX92303.1 - 6.5e-20 71.4 0.4 1.3e-19 70.4 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF240 PF03086.14 EAX92303.1 - 0.3 11.0 1.4 6.5 6.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF240) Actin PF00022.19 EAX92304.1 - 7.2e-139 462.9 0.0 2.7e-138 461.0 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX92304.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT ArfGap PF01412.18 EAX92305.1 - 1.5e-26 92.8 1.7 2.1e-26 92.3 1.7 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ran_BP1 PF00638.18 EAX92306.1 - 2.9e-41 140.5 0.1 4.7e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain DCP1 PF06058.13 EAX92306.1 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH1 PF00568.23 EAX92306.1 - 0.0018 18.2 0.6 0.0042 17.0 0.6 1.6 1 1 0 1 1 1 1 WH1 domain PALP PF00291.25 EAX92308.1 - 2.5e-37 128.9 0.0 2.8e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 EAX92309.1 - 3e-50 171.3 0.1 3.5e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3839 PF12943.7 EAX92311.1 - 1.1e-156 519.5 13.1 1.3e-156 519.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92311.1 - 0.21 11.5 1.5 0.6 10.0 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX92311.1 - 0.74 10.3 5.8 1.4 9.4 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Nab1 PF04902.12 EAX92312.1 - 0.018 15.5 1.6 0.021 15.2 1.6 1.1 1 0 0 1 1 1 0 Conserved region in Nab1 DUF3839 PF12943.7 EAX92313.1 - 7.9e-113 375.9 4.1 9.4e-113 375.6 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX92313.1 - 0.046 13.2 0.2 0.055 13.0 0.2 1.2 1 0 0 1 1 1 0 Z1 domain DUF5398 PF17376.2 EAX92313.1 - 0.28 11.8 1.5 0.5 11.0 0.2 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5398) TMP PF05017.14 EAX92314.1 - 0.12 13.0 6.7 6.8 7.8 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX92314.1 - 1.9 8.4 6.9 2.1 8.4 6.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX92315.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PapD_N PF00345.20 EAX92317.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX92317.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX92317.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX92318.1 - 0.021 15.2 0.9 0.027 14.9 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX92318.1 - 1.7 7.6 4.3 1.8 7.5 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX92318.1 - 6.3 6.8 8.0 6.8 6.7 8.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX92319.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX92320.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase_Tyr PF07714.17 EAX92322.1 - 1.2e-21 77.2 0.1 3.6e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX92322.1 - 1.1e-14 54.5 0.5 3.5e-14 52.8 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain DUF505 PF04458.12 EAX92322.1 - 0.049 12.0 0.2 0.35 9.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF505) DUF4116 PF13475.6 EAX92322.1 - 0.1 12.3 3.4 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Chlam_PMP PF02415.17 EAX92323.1 - 6.9 7.4 8.6 2.6 8.7 0.4 3.8 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ank_2 PF12796.7 EAX92324.1 - 4e-37 126.7 1.3 2.5e-12 47.2 0.0 6.7 3 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92324.1 - 1.4e-27 95.7 4.2 4.8e-06 27.0 0.0 7.4 8 1 0 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92324.1 - 5.4e-26 90.3 0.3 4.6e-07 30.0 0.0 8.6 8 1 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92324.1 - 1.1e-22 77.6 4.6 0.028 14.9 0.0 11.6 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 EAX92324.1 - 2.9e-18 65.4 0.1 0.22 12.1 0.0 9.0 8 1 0 8 8 8 4 Ankyrin repeat DUF3802 PF12290.8 EAX92324.1 - 0.037 14.5 0.1 0.16 12.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) SSPI PF14098.6 EAX92324.1 - 0.95 9.7 3.3 1 9.6 0.9 2.1 2 0 0 2 2 2 0 Small, acid-soluble spore protein I Got1 PF04178.12 EAX92325.1 - 4.2e-12 46.5 14.5 5e-12 46.2 14.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Saf_2TM PF18303.1 EAX92325.1 - 0.041 13.5 10.3 0.7 9.5 4.9 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2085 PF09858.9 EAX92325.1 - 1.6 9.3 11.4 0.13 12.8 6.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) Glyco_hydro_47 PF01532.20 EAX92326.1 - 8.1e-15 54.7 0.2 8.3e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CUTL PF16557.5 EAX92326.1 - 0.14 12.4 1.1 5.1 7.3 0.0 2.7 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB zf-CCCH PF00642.24 EAX92327.1 - 9.2e-08 31.8 4.6 1.3e-07 31.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAX92327.1 - 7.5e-05 23.4 0.2 0.0001 23.0 0.2 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EAX92327.1 - 0.00016 21.6 6.0 0.00026 21.0 6.0 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAX92327.1 - 0.0026 17.5 3.2 0.004 16.9 3.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAX92327.1 - 0.72 10.4 3.2 1.2 9.8 3.2 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PRA-PH PF01503.17 EAX92328.1 - 0.072 13.5 1.1 13 6.3 3.3 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase PSP PF04046.16 EAX92329.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Sas10_Utp3 PF04000.15 EAX92330.1 - 0.025 15.2 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DNA_pol_phi PF04931.13 EAX92330.1 - 0.72 7.9 7.0 0.73 7.9 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi CBM_4_9 PF02018.17 EAX92331.1 - 0.0038 17.5 0.4 0.42 10.9 0.0 3.7 3 0 0 3 3 3 1 Carbohydrate binding domain EphA2_TM PF14575.6 EAX92331.1 - 0.023 15.5 0.0 0.34 11.8 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pilin_N PF07790.11 EAX92331.1 - 0.059 14.3 0.3 24 5.9 0.5 3.0 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal UvrB_inter PF17757.1 EAX92331.1 - 0.076 13.2 0.1 0.4 10.9 0.1 2.3 1 0 0 1 1 1 0 UvrB interaction domain TMEM154 PF15102.6 EAX92331.1 - 0.19 11.6 5.8 0.027 14.4 1.7 1.6 2 0 0 2 2 2 0 TMEM154 protein family NVEALA PF14055.6 EAX92331.1 - 0.6 10.1 2.1 0.81 9.7 0.5 2.0 2 0 0 2 2 2 0 NVEALA protein DUF4384 PF14326.6 EAX92332.1 - 0.0047 17.0 8.4 12 6.1 0.0 6.7 6 0 0 6 6 6 1 Domain of unknown function (DUF4384) NifU_N PF01592.16 EAX92332.1 - 0.2 11.8 0.2 1.2e+02 2.8 0.0 4.3 6 0 0 6 6 6 0 NifU-like N terminal domain DNA_pol_B_2 PF03175.13 EAX92334.1 - 4.2e-09 35.8 1.6 5.3e-09 35.5 0.8 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX92334.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX92335.1 - 0.06 13.2 0.1 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX92336.1 - 2.3e-28 99.4 1.8 3.9e-28 98.7 1.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Myb_DNA-binding PF00249.31 EAX92337.1 - 4.1e-27 94.1 4.9 1.5e-13 50.7 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92337.1 - 1.9e-22 79.3 6.8 1e-15 57.7 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX92337.1 - 6.1e-05 23.0 0.5 0.017 15.2 0.0 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX92337.1 - 0.0008 19.3 2.3 0.0046 16.8 0.5 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX92337.1 - 0.018 15.4 11.0 0.15 12.5 0.4 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX92337.1 - 0.068 13.4 1.5 0.17 12.1 1.0 2.0 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX92337.1 - 0.075 13.1 0.7 2.6 8.2 0.1 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PepSY PF03413.19 EAX92338.1 - 0.13 12.9 0.2 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain CTD_bind PF04818.13 EAX92338.1 - 0.14 13.0 2.6 3.6 8.5 0.6 2.8 2 1 0 2 2 2 0 RNA polymerase II-binding domain. NES_C_h PF18208.1 EAX92338.1 - 0.57 10.5 7.3 0.18 12.1 3.9 1.8 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Ank_2 PF12796.7 EAX92339.1 - 1.7e-57 192.0 9.1 8.4e-12 45.5 0.4 8.6 5 3 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92339.1 - 1.3e-39 129.6 16.8 0.00038 20.7 0.0 16.4 17 0 0 17 17 17 9 Ankyrin repeat Ank_5 PF13857.6 EAX92339.1 - 2.3e-38 129.7 7.3 3.7e-06 27.1 0.0 12.1 5 2 9 14 14 14 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92339.1 - 2.6e-37 126.7 7.5 1.2e-06 28.9 0.1 11.7 4 2 10 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX92339.1 - 4.1e-20 71.3 3.3 0.047 14.2 0.0 11.6 14 0 0 14 14 14 4 Ankyrin repeat DUF3447 PF11929.8 EAX92339.1 - 4.7e-09 36.1 1.1 4.7e-09 36.1 1.1 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) C2 PF00168.30 EAX92342.1 - 9.8e-23 80.4 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 C2 domain F5_F8_type_C PF00754.25 EAX92343.1 - 3.5e-06 27.2 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain MULE PF10551.9 EAX92344.1 - 4.5e-11 43.0 0.1 8.8e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX92344.1 - 0.14 12.3 2.3 0.27 11.4 2.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain PWI PF01480.17 EAX92344.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 PWI domain Abi_C PF14355.6 EAX92345.1 - 3.3 7.9 6.9 1.2 9.3 2.4 2.7 2 0 0 2 2 2 0 Abortive infection C-terminus Endosulfine PF04667.17 EAX92347.1 - 3.7e-05 23.8 0.0 4.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Stevor PF17410.2 EAX92348.1 - 0.044 13.3 2.0 0.065 12.8 2.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 EAX92348.1 - 0.052 12.4 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Amnionless Chlam_PMP PF02415.17 EAX92349.1 - 0.0066 16.9 22.4 0.078 13.5 0.0 6.0 6 0 0 6 6 6 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5106 PF17127.4 EAX92350.1 - 0.041 14.2 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PapD_N PF00345.20 EAX92352.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX92352.1 - 0.12 12.3 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX92353.1 - 0.021 15.2 0.7 0.032 14.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX92353.1 - 1.9 7.4 4.2 2.1 7.3 4.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX92353.1 - 3.1 8.5 6.5 6.6 7.4 6.5 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX92353.1 - 6.5 6.8 7.3 6.9 6.7 7.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX92354.1 - 0.013 15.5 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX92355.1 - 0.0083 16.1 6.0 0.013 15.5 6.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX92356.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CEND1 PF15677.5 EAX92358.1 - 0.022 15.3 0.2 0.061 13.9 0.2 1.8 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 F5_F8_type_C PF00754.25 EAX92359.1 - 3.2e-07 30.5 0.0 3.4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain DUF3839 PF12943.7 EAX92361.1 - 4.2e-157 520.8 13.1 5.2e-157 520.5 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX92361.1 - 0.12 12.8 0.3 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX92361.1 - 0.65 10.5 6.8 2.2 8.8 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX92362.1 - 0.0069 16.9 0.1 0.012 16.2 0.1 1.4 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX92362.1 - 0.027 14.3 1.1 0.073 12.9 1.1 1.8 1 1 0 1 1 1 0 KilA-N domain Pox_D5 PF03288.16 EAX92363.1 - 0.00011 22.6 3.1 0.00066 20.1 3.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX92363.1 - 0.098 12.6 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Beta-lactamase PF00144.24 EAX92364.1 - 7e-32 111.0 0.0 1.1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DHHC PF01529.20 EAX92364.1 - 0.55 10.3 17.1 0.41 10.7 3.8 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase Gly_rich PF12810.7 EAX92365.1 - 7.9e-54 183.1 52.8 1e-53 182.8 52.8 1.1 1 0 0 1 1 1 1 Glycine rich protein Phospholip_B PF04916.13 EAX92366.1 - 4.9e-115 385.1 7.4 5.9e-115 384.9 7.4 1.0 1 0 0 1 1 1 1 Phospholipase B Occludin_ELL PF07303.13 EAX92366.1 - 0.063 14.0 0.0 0.62 10.8 0.0 2.3 2 0 0 2 2 2 0 Occludin homology domain PSI PF01437.25 EAX92366.1 - 4 8.0 7.1 8.6 7.0 7.1 1.5 1 0 0 1 1 1 0 Plexin repeat Ndc1_Nup PF09531.10 EAX92368.1 - 7.7 5.1 11.5 13 4.3 11.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup C2 PF00168.30 EAX92369.1 - 1.9e-25 89.2 0.1 3.5e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 C2 domain UPF0242 PF06785.11 EAX92370.1 - 0.00039 20.6 68.5 0.0008 19.6 23.6 4.5 1 1 3 4 4 4 3 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 EAX92370.1 - 0.0011 18.6 43.6 0.0029 17.2 18.5 3.5 1 1 2 3 3 3 2 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EAX92370.1 - 0.002 18.1 58.5 0.011 15.8 14.9 4.5 2 1 3 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 EAX92370.1 - 0.0024 16.1 15.9 0.0024 16.1 15.9 3.1 1 1 2 3 3 3 1 HOOK protein CALCOCO1 PF07888.11 EAX92370.1 - 0.0053 15.7 47.5 0.015 14.2 35.6 2.3 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Fungal_TACC PF12709.7 EAX92370.1 - 0.018 15.5 6.4 0.018 15.5 6.4 6.5 1 1 4 6 6 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins AAA_13 PF13166.6 EAX92370.1 - 0.022 13.5 55.8 0.19 10.4 34.1 2.1 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 EAX92370.1 - 0.043 14.3 51.1 0.032 14.7 16.4 3.0 1 1 2 3 3 3 0 Fez1 HrpB7 PF09486.10 EAX92370.1 - 0.053 13.9 22.2 0.93 9.9 1.0 4.3 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 EAX92370.1 - 0.066 13.4 50.4 0.17 12.1 11.2 3.7 3 1 1 4 4 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EAX92370.1 - 0.074 12.4 38.8 0.38 10.0 15.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 EAX92370.1 - 0.093 12.1 55.0 0.31 10.4 36.8 3.4 1 1 2 3 3 3 0 Tropomyosin DUF1664 PF07889.12 EAX92370.1 - 0.21 11.7 46.0 0.19 11.8 10.6 4.7 2 1 1 5 5 5 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EAX92370.1 - 0.38 9.6 62.1 0.013 14.4 16.7 3.6 2 1 2 4 4 4 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 EAX92370.1 - 0.49 9.9 36.6 0.06 12.9 19.1 3.6 1 1 2 3 3 3 0 PspA/IM30 family Baculo_PEP_C PF04513.12 EAX92370.1 - 0.59 10.2 25.8 2.8 8.0 9.6 3.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 EAX92370.1 - 0.61 9.7 60.5 0.3 10.8 34.0 3.9 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF3209 PF11483.8 EAX92370.1 - 0.65 10.5 12.9 1.2 9.6 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3209) Filament PF00038.21 EAX92370.1 - 0.69 9.4 58.1 1.3 8.5 34.8 3.5 1 1 2 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 EAX92370.1 - 0.69 7.3 47.2 0.63 7.5 45.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.16 EAX92370.1 - 1.3 9.3 42.2 0.57 10.4 8.4 4.5 1 1 3 4 4 4 0 Flagellar FliJ protein T3SSipB PF16535.5 EAX92370.1 - 1.5 9.3 36.2 0.11 13.0 6.5 4.4 2 1 3 5 5 4 0 Type III cell invasion protein SipB Chordopox_L2 PF05803.12 EAX92370.1 - 1.7 8.6 5.9 0.26 11.2 1.4 1.9 2 0 0 2 2 1 0 Chordopoxvirus L2 protein SlyX PF04102.12 EAX92370.1 - 1.7 9.3 39.3 0.18 12.4 4.3 6.8 3 2 3 6 6 6 0 SlyX DUF641 PF04859.12 EAX92370.1 - 1.8 8.9 41.5 0.087 13.2 8.6 4.8 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 EAX92370.1 - 2 9.0 60.0 0.034 14.7 20.4 4.4 2 2 2 4 4 4 0 Apg6 coiled-coil region CSN5_C PF18323.1 EAX92370.1 - 3.6 8.5 28.7 2.5 9.1 9.0 4.7 3 1 1 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain HemX PF04375.14 EAX92370.1 - 3.9 6.7 39.6 0.32 10.2 7.1 3.4 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase PTN_MK_C PF01091.18 EAX92370.1 - 5.4 7.5 7.7 14 6.1 0.4 3.4 3 1 0 3 3 2 0 PTN/MK heparin-binding protein family, C-terminal domain HMMR_N PF15905.5 EAX92370.1 - 5.9 6.3 67.7 1.8 8.0 23.0 3.5 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Retrotrans_gag PF03732.17 EAX92370.1 - 6.3 7.1 21.6 3.9 7.8 0.8 5.2 2 1 2 4 4 4 0 Retrotransposon gag protein DUF812 PF05667.11 EAX92370.1 - 8.1 5.2 60.3 1.8e+04 -9.8 60.3 2.4 1 1 0 1 1 0 0 Protein of unknown function (DUF812) Furin-like_2 PF15913.5 EAX92371.1 - 0.0013 18.9 14.2 0.0013 18.9 14.2 4.2 1 1 3 4 4 4 3 Furin-like repeat, cysteine-rich Ribosomal_L27e PF01777.18 EAX92372.1 - 2.2e-21 76.0 6.8 2.8e-21 75.6 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAX92372.1 - 0.0062 16.4 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAX92372.1 - 0.16 11.4 0.1 0.18 11.2 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FmdE PF02663.14 EAX92374.1 - 2 8.5 5.2 2.6 8.1 5.2 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon HTH_9 PF08221.11 EAX92375.1 - 1.7e-05 24.9 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RIX1 PF08167.12 EAX92376.1 - 0.00061 19.6 2.9 0.12 12.1 0.0 3.4 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Ku_PK_bind PF08785.11 EAX92376.1 - 0.032 14.4 1.3 1.8 8.7 0.1 3.4 3 0 0 3 3 3 0 Ku C terminal domain like DUF1955 PF09205.10 EAX92376.1 - 1.6 8.5 10.5 7.1 6.3 1.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF1955) DUF3385 PF11865.8 EAX92376.1 - 2.6 7.9 13.4 0.29 11.0 0.7 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Ank_4 PF13637.6 EAX92377.1 - 6.8e-52 173.2 7.2 3.2e-14 53.1 0.1 8.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92377.1 - 4.7e-51 171.3 28.1 1.6e-14 54.3 0.6 5.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92377.1 - 5.5e-51 168.9 5.8 1.3e-07 31.7 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX92377.1 - 3.9e-37 122.0 11.7 2.2e-05 24.5 0.1 9.2 9 1 1 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX92377.1 - 1e-36 124.7 16.3 5.5e-36 122.4 9.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX92377.1 - 4.8e-32 109.6 11.2 2.9e-10 40.2 0.3 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX92377.1 - 0.004 17.4 0.6 22 5.4 0.0 4.0 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase RL PF17797.1 EAX92377.1 - 0.038 13.9 4.7 0.66 10.0 0.1 4.0 4 0 0 4 4 4 0 RL domain Ank_4 PF13637.6 EAX92378.1 - 1.2e-56 188.4 14.0 3.3e-11 43.5 0.1 9.6 4 1 7 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92378.1 - 1.1e-51 173.3 34.3 8.3e-18 64.8 4.4 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92378.1 - 2.6e-49 163.6 5.9 5.9e-08 32.8 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX92378.1 - 9e-38 124.0 10.6 5.5e-05 23.3 0.0 10.2 11 0 0 11 11 11 6 Ankyrin repeat DUF3447 PF11929.8 EAX92378.1 - 6e-37 125.4 5.1 6e-37 125.4 5.1 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX92378.1 - 5.3e-33 112.6 3.6 1.6e-09 37.8 0.0 6.6 5 2 3 8 8 8 5 Ankyrin repeats (many copies) RL PF17797.1 EAX92378.1 - 0.13 12.2 7.9 1.2 9.1 0.1 4.7 4 1 0 5 5 5 0 RL domain COG5 PF10392.9 EAX92379.1 - 2.9e-11 43.6 1.9 2.9e-11 43.6 1.9 3.7 3 2 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EAX92379.1 - 0.0052 16.8 0.6 0.0052 16.8 0.6 3.5 4 0 0 4 4 4 1 Vps51/Vps67 MRPL52 PF18699.1 EAX92379.1 - 0.0096 16.1 4.1 0.43 10.8 0.1 2.7 2 0 0 2 2 2 1 Mitoribosomal protein mL52 Baculo_PEP_C PF04513.12 EAX92379.1 - 0.12 12.4 12.6 0.87 9.6 0.0 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3053 PF11254.8 EAX92379.1 - 0.12 11.9 6.1 2.3 7.7 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) PUB PF09409.10 EAX92379.1 - 0.16 11.9 1.3 1.5 8.8 0.4 2.5 1 1 1 2 2 2 0 PUB domain Syntaxin-18_N PF10496.9 EAX92379.1 - 0.2 12.0 3.3 0.13 12.5 0.6 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus SKA2 PF16740.5 EAX92379.1 - 0.33 10.7 6.5 0.31 10.8 2.1 3.2 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 ADIP PF11559.8 EAX92379.1 - 0.8 9.8 10.1 0.47 10.5 2.6 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 EAX92379.1 - 0.92 9.9 6.1 3.4 8.1 1.3 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ank PF00023.30 EAX92380.1 - 2.8e-14 52.8 0.6 0.0018 18.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX92380.1 - 5.6e-14 52.5 0.3 7.1e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92380.1 - 5.6e-13 49.1 0.2 3.5e-06 27.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92380.1 - 5.2e-09 35.6 0.2 0.091 13.4 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX92380.1 - 5.1e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) DUF2733 PF10813.8 EAX92380.1 - 0.25 11.1 2.3 0.27 11.0 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) E1-E2_ATPase PF00122.20 EAX92381.1 - 1.7e-06 27.7 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase PEGA PF08308.11 EAX92382.1 - 0.16 11.9 0.4 7.6 6.5 0.0 2.7 3 0 0 3 3 3 0 PEGA domain PhoLip_ATPase_C PF16212.5 EAX92383.1 - 9.2e-26 91.1 28.5 1.2e-25 90.8 28.5 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Ank_4 PF13637.6 EAX92384.1 - 1.5e-13 50.9 0.2 4.8e-08 33.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92384.1 - 2.6e-11 42.7 0.2 0.0017 18.6 0.1 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX92384.1 - 1.9e-10 41.2 0.0 3.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92384.1 - 6.6e-10 39.0 0.0 0.047 14.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX92384.1 - 2.1e-09 37.4 0.8 9.6e-06 25.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA-synt_2 PF00152.20 EAX92385.1 - 2.2e-87 293.1 0.0 1.8e-86 290.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAX92385.1 - 5.1e-10 39.2 0.2 1e-09 38.3 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3510 PF12022.8 EAX92385.1 - 0.044 14.2 0.6 1.1 9.7 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Ribosomal_S9 PF00380.19 EAX92386.1 - 2.1e-33 115.4 0.1 2.4e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ChapFlgA_N PF17656.1 EAX92386.1 - 0.027 14.6 0.2 0.9 9.8 0.0 2.2 1 1 1 2 2 2 0 FlgA N-terminal domain Baculo_PEP_C PF04513.12 EAX92387.1 - 0.0034 17.4 23.0 0.18 11.8 1.5 4.5 3 2 2 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Sec23_helical PF04815.15 EAX92387.1 - 0.16 11.8 2.1 0.44 10.4 0.0 2.7 2 1 0 3 3 3 0 Sec23/Sec24 helical domain ABC_tran_CTD PF16326.5 EAX92387.1 - 2.7 8.3 10.6 6 7.2 0.0 4.8 4 1 2 6 6 6 0 ABC transporter C-terminal domain DUF2802 PF10975.8 EAX92387.1 - 8.9 6.5 8.6 0.7 10.1 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) DUF3447 PF11929.8 EAX92388.1 - 1e-17 63.9 2.2 1e-17 63.9 2.2 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX92388.1 - 1.4e-11 44.4 0.2 1.7e-06 28.2 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92388.1 - 1.9e-11 44.4 0.3 3.3e-09 37.2 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92388.1 - 9e-11 41.7 1.3 6.3e-05 23.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAX92388.1 - 1.7e-09 37.1 0.9 0.02 15.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX92388.1 - 3.6e-08 33.8 2.7 2.2e-07 31.3 0.1 3.6 3 1 2 5 5 5 1 Ankyrin repeats (many copies) RNase_H_2 PF13482.6 EAX92388.1 - 0.075 13.0 3.4 2.1 8.3 1.0 3.0 2 1 1 3 3 3 0 RNase_H superfamily CH PF00307.31 EAX92389.1 - 1e-42 144.7 2.8 8.7e-24 83.8 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EAX92389.1 - 5.3e-09 35.8 0.3 8.5e-06 25.5 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_7 PF13499.6 EAX92389.1 - 4.6e-06 27.0 4.3 6.2e-06 26.6 1.3 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EAX92389.1 - 5.7e-05 22.7 0.0 0.00033 20.4 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain ApoLp-III PF07464.11 EAX92389.1 - 8.4e-05 22.7 7.9 0.009 16.1 1.1 3.0 3 1 0 3 3 2 2 Apolipophorin-III precursor (apoLp-III) EF-hand_1 PF00036.32 EAX92389.1 - 0.00028 20.2 0.1 0.0074 15.8 0.0 3.0 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.10 EAX92389.1 - 0.004 17.2 0.2 0.016 15.3 0.0 2.2 2 0 0 2 2 1 1 Ca2+ insensitive EF hand COG2 PF06148.11 EAX92389.1 - 0.015 15.3 3.8 0.015 15.3 3.8 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC4 PF12896.7 EAX92389.1 - 0.059 12.9 3.1 0.61 9.6 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 COG5 PF10392.9 EAX92389.1 - 0.062 13.5 0.7 0.17 12.1 0.7 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Ubiq_cyt_C_chap PF03981.12 EAX92389.1 - 0.1 12.7 1.6 5.8 7.0 0.1 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone NPV_P10 PF05531.12 EAX92389.1 - 0.19 12.2 5.3 1.9 9.0 1.6 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein NAPRTase_N PF17767.1 EAX92389.1 - 0.22 11.9 1.6 4.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Prefoldin PF02996.17 EAX92389.1 - 0.44 10.5 7.4 0.38 10.7 0.4 4.0 4 0 0 4 4 4 0 Prefoldin subunit Tropomyosin_1 PF12718.7 EAX92389.1 - 0.5 10.5 11.6 0.062 13.5 6.5 2.2 2 0 0 2 2 2 0 Tropomyosin like Fez1 PF06818.15 EAX92389.1 - 0.57 10.6 9.7 1.3 9.5 3.8 2.4 1 1 1 2 2 2 0 Fez1 YbaB_DNA_bd PF02575.16 EAX92389.1 - 0.71 10.1 6.1 7.9 6.8 0.2 3.5 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family DUF1664 PF07889.12 EAX92389.1 - 0.79 9.8 6.5 0.52 10.3 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EAX92389.1 - 1.9 9.0 12.0 2.1 8.9 1.6 3.9 2 2 1 3 3 3 0 Spectrin repeat MscS_porin PF12795.7 EAX92389.1 - 2.1 7.8 10.2 0.092 12.3 2.8 2.3 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain FliJ PF02050.16 EAX92389.1 - 2.3 8.4 9.2 0.55 10.5 3.8 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 EAX92389.1 - 2.8 6.7 15.2 1.3 7.9 6.4 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EAX92389.1 - 3.1 7.8 5.3 1.4 9.0 0.5 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EAX92389.1 - 5.5 6.5 6.3 0.97 9.0 1.4 2.3 3 0 0 3 3 3 0 fzo-like conserved region HrpB7 PF09486.10 EAX92389.1 - 5.6 7.3 12.1 4.8 7.6 2.3 3.2 3 1 0 3 3 2 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.11 EAX92389.1 - 6 7.2 6.0 3 8.2 0.2 3.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 EAX92389.1 - 6.4 6.6 11.4 6.9 6.5 6.7 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain OmpH PF03938.14 EAX92389.1 - 9.7 6.5 22.3 0.19 12.1 2.3 3.7 1 1 1 2 2 1 0 Outer membrane protein (OmpH-like) PSP PF04046.16 EAX92390.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92391.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX92392.1 - 6.1e-37 125.5 23.3 1.8e-32 111.2 13.4 4.0 4 1 1 5 5 5 3 Phage tail repeat like BRO1 PF03097.18 EAX92392.1 - 0.039 12.8 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain DUF3839 PF12943.7 EAX92393.1 - 5.1e-157 520.5 14.1 6.4e-157 520.2 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX92393.1 - 0.48 10.9 7.2 2.5 8.6 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX92393.1 - 1.3 9.6 5.3 0.95 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Gal_mutarotas_3 PF18080.1 EAX92396.1 - 0.0089 16.0 2.0 0.025 14.5 0.1 2.1 1 1 1 2 2 2 1 Galactose mutarotase-like fold domain DUF5347 PF17282.2 EAX92398.1 - 0.082 13.2 0.3 0.31 11.4 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5347) BBS2_Mid PF14783.6 EAX92401.1 - 0.0042 17.1 1.4 8 6.6 0.2 3.5 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 EAX92401.1 - 0.046 12.2 1.6 0.068 11.7 1.6 1.2 1 0 0 1 1 1 0 Utp8 family WD40 PF00400.32 EAX92401.1 - 1 10.4 7.0 3.8 8.6 0.1 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat Peptidase_S28 PF05577.12 EAX92402.1 - 9.9e-81 271.7 6.7 1.2e-80 271.4 6.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EAX92402.1 - 0.0088 15.5 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3827 PF12877.7 EAX92402.1 - 0.015 13.8 2.5 0.021 13.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Hydrolase_4 PF12146.8 EAX92402.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TMEM154 PF15102.6 EAX92402.1 - 0.038 13.9 0.2 0.075 12.9 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family GP41 PF00517.17 EAX92402.1 - 0.12 12.3 1.2 0.21 11.4 0.5 1.8 2 0 0 2 2 2 0 Retroviral envelope protein FCH PF00611.23 EAX92402.1 - 0.13 12.5 0.1 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain LRR19-TM PF15176.6 EAX92402.1 - 3.7 7.6 7.4 0.57 10.2 0.8 2.7 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain IMUP PF15761.5 EAX92404.1 - 8.8 7.1 16.3 1.9 9.2 0.1 2.8 3 0 0 3 3 3 0 Immortalisation up-regulated protein LRR_5 PF13306.6 EAX92406.1 - 1.1e-11 44.8 1.1 4e-10 39.8 0.3 2.3 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92406.1 - 0.086 12.6 0.0 0.67 9.8 0.0 2.4 3 1 0 3 3 3 0 Leucine rich repeat DHR-2 PF06920.13 EAX92407.1 - 3.1e-10 39.3 0.5 3.1e-10 39.3 0.5 2.2 3 0 0 3 3 3 1 Dock homology region 2 TBCA PF02970.16 EAX92407.1 - 0.12 12.8 0.3 0.28 11.5 0.3 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A AbiJ_NTD4 PF18863.1 EAX92408.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX92408.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein Pox_A32 PF04665.12 EAX92409.1 - 1.6e-08 34.3 1.0 3.5e-08 33.2 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX92409.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX92409.1 - 0.065 13.1 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4107 PF13389.6 EAX92410.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) HAUS-augmin3 PF14932.6 EAX92411.1 - 0.0089 15.6 1.7 0.013 15.1 1.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Arm-DNA-bind_5 PF17293.2 EAX92411.1 - 10 6.7 14.0 2.4 8.7 7.4 3.1 2 2 0 2 2 2 0 Arm DNA-binding domain PagP PF07017.11 EAX92412.1 - 0.076 12.4 3.0 0.22 10.9 0.1 2.0 1 1 1 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP F-box PF00646.33 EAX92415.1 - 0.087 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 F-box domain DUF3839 PF12943.7 EAX92416.1 - 1e-153 509.8 11.5 1.3e-153 509.4 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92416.1 - 0.049 13.5 0.9 0.2 11.5 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX92416.1 - 0.94 10.0 4.1 3.5 8.1 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Y_Y_Y PF07495.13 EAX92418.1 - 0.0011 18.9 1.7 0.13 12.2 0.3 2.6 2 0 0 2 2 2 2 Y_Y_Y domain ZirS_C PF16583.5 EAX92418.1 - 0.025 14.2 0.2 0.45 10.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Sigma_reg_N PF13800.6 EAX92418.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3169 PF11368.8 EAX92418.1 - 0.074 12.6 0.4 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PapD_N PF00345.20 EAX92419.1 - 0.046 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX92419.1 - 0.056 13.4 0.4 0.085 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol3_a_NII PF11490.8 EAX92419.1 - 0.27 11.2 5.4 0.089 12.7 0.8 2.1 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Amidase02_C PF12123.8 EAX92420.1 - 0.011 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX92421.1 - 2.2e-72 242.5 4.1 3e-72 242.1 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX92424.1 - 5.2e-11 42.4 6.2 5e-09 36.1 1.7 4.8 5 1 1 6 6 6 2 Phage tail repeat like DUF4795 PF16043.5 EAX92424.1 - 0.01 15.4 14.0 0.061 12.9 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX92424.1 - 0.019 15.5 4.3 21 5.7 0.0 4.1 4 0 0 4 4 4 0 YmaF family DUF5017 PF16409.5 EAX92424.1 - 0.039 13.4 2.2 2.9 7.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5017) TMP PF05017.14 EAX92426.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX92427.1 - 0.039 13.8 0.8 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PSP FxsA PF04186.13 EAX92428.1 - 0.0094 16.1 1.8 0.077 13.1 0.1 2.2 2 0 0 2 2 2 2 FxsA cytoplasmic membrane protein Peptidase_S28 PF05577.12 EAX92429.1 - 2.6e-44 151.7 8.7 4.6e-44 150.9 8.7 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 AJAP1_PANP_C PF15298.6 EAX92429.1 - 0.0048 17.1 0.4 0.01 16.1 0.4 1.5 1 0 0 1 1 1 1 AJAP1/PANP C-terminus TMEM154 PF15102.6 EAX92429.1 - 0.0058 16.5 0.7 0.014 15.3 0.4 1.8 2 0 0 2 2 2 1 TMEM154 protein family Mucin PF01456.17 EAX92429.1 - 0.033 14.2 8.8 0.055 13.5 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_gE PF02480.16 EAX92429.1 - 0.095 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 EAX92429.1 - 0.1 12.5 0.0 0.56 10.1 0.0 2.1 2 1 1 3 3 3 0 Rifin PT PF04886.12 EAX92429.1 - 3 7.5 43.4 2.2e+02 1.5 43.4 2.7 1 1 0 1 1 1 0 PT repeat SKG6 PF08693.10 EAX92429.1 - 3.6 7.1 6.0 6.1 6.3 6.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zemlya PF17646.1 EAX92430.1 - 0.073 13.4 2.1 0.88 10.0 0.0 3.3 3 0 0 3 3 3 0 Closterovirus 1a polyprotein central region MULE PF10551.9 EAX92432.1 - 1.5e-10 41.4 0.1 4.8e-10 39.7 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain HTH_Tnp_1_2 PF13022.6 EAX92432.1 - 0.019 15.1 3.7 0.059 13.5 0.2 2.9 2 1 1 3 3 3 0 Helix-turn-helix of insertion element transposase Salp15 PF12115.8 EAX92432.1 - 7.5 7.0 8.5 0.68 10.4 0.3 2.6 3 0 0 3 3 3 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Trypan_PARP PF05887.11 EAX92433.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX92433.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX92434.1 - 4.7e-149 494.5 11.3 6.1e-149 494.1 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX92434.1 - 0.0031 18.0 0.3 0.032 14.7 0.0 2.0 2 0 0 2 2 2 1 Fez1 KELK PF15796.5 EAX92434.1 - 0.43 11.1 6.3 1.9 9.0 1.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX92435.1 - 0.025 15.0 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX92435.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX92436.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX92437.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Fe-ADH PF00465.19 EAX92438.1 - 2e-105 352.6 0.2 2.3e-105 352.4 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX92438.1 - 1.6e-14 54.3 1.9 2.4e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase LRR_5 PF13306.6 EAX92439.1 - 3.8e-140 460.1 108.8 6.7e-34 116.6 12.5 6.0 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92439.1 - 2.3e-29 100.9 4.4 0.00088 19.0 0.1 9.9 6 3 5 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 EAX92439.1 - 3.8e-06 27.1 17.9 6 7.4 0.1 9.8 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) DUF1308 PF07000.11 EAX92439.1 - 0.0039 17.1 3.0 4.3 7.2 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1308) CBM_20 PF00686.19 EAX92439.1 - 0.013 15.3 0.0 8.7 6.3 0.0 4.1 3 1 2 5 5 5 0 Starch binding domain DUF4372 PF14294.6 EAX92439.1 - 0.079 13.1 0.0 30 4.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4372) DUF4791 PF16039.5 EAX92439.1 - 0.2 11.1 4.2 2.9 7.4 0.0 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4791) AIF_C PF14721.6 EAX92440.1 - 0.056 13.8 0.6 0.079 13.3 0.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term F-protein PF00469.20 EAX92440.1 - 0.073 12.7 0.6 0.095 12.3 0.6 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef NPL PF17800.1 EAX92440.1 - 0.088 13.4 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin-like domain Na_sulph_symp PF00939.19 EAX92442.1 - 1.5e-71 241.9 35.9 1.9e-71 241.6 35.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAX92442.1 - 2.3e-37 128.8 33.4 2.3e-37 128.8 33.4 2.5 1 1 1 2 2 2 2 Citrate transporter Adap_comp_sub PF00928.21 EAX92443.1 - 2e-13 50.3 0.1 5.1e-13 49.0 0.1 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Gly_rich PF12810.7 EAX92444.1 - 4.8e-62 210.1 29.1 5.6e-62 209.8 29.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX92445.1 - 4.3e-60 203.6 28.7 5.5e-60 203.3 28.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Peptidase_C48 PF02902.19 EAX92446.1 - 4.9e-13 49.4 5.2 6.9e-13 48.9 5.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FOP_dimer PF09398.10 EAX92447.1 - 0.00035 20.8 0.1 0.00077 19.7 0.0 1.5 2 0 0 2 2 2 1 FOP N terminal dimerisation domain PI3_PI4_kinase PF00454.27 EAX92448.1 - 2.5e-50 171.7 0.3 9.4e-50 169.8 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EAX92448.1 - 7e-16 57.7 0.1 2.9e-15 55.8 0.1 2.2 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 EAX92448.1 - 3e-15 56.3 1.1 3e-15 56.3 1.1 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 EAX92448.1 - 9.2e-13 48.4 3.0 7.4e-12 45.5 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EAX92448.1 - 7.3e-08 32.7 2.5 1.6e-07 31.7 0.8 2.5 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EAX92448.1 - 0.00091 19.6 0.0 1 9.8 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats BP28CT PF08146.12 EAX92448.1 - 0.005 16.7 4.5 1.4 8.7 0.3 4.3 3 1 1 4 4 4 2 BP28CT (NUC211) domain CLASP_N PF12348.8 EAX92448.1 - 0.013 15.1 5.8 0.59 9.7 0.1 4.1 4 0 0 4 4 4 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 EAX92448.1 - 0.03 14.9 4.6 1.4 9.5 0.1 4.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region SecA_SW PF07516.13 EAX92448.1 - 2.2 8.3 5.4 3 7.9 2.6 2.8 2 1 0 2 2 2 0 SecA Wing and Scaffold domain Pkinase PF00069.25 EAX92449.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EAX92449.1 - 6.4e-05 22.6 0.1 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family AAA-ATPase_like PF09820.9 EAX92449.1 - 0.00045 19.7 0.3 0.00079 18.9 0.3 1.4 1 0 0 1 1 1 1 Predicted AAA-ATPase APH PF01636.23 EAX92449.1 - 0.024 14.6 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTP_transf_like PF01467.26 EAX92451.1 - 3e-43 147.5 0.0 1.6e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EAX92451.1 - 0.00017 21.5 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 EAX92451.1 - 0.0064 15.7 0.1 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Pantoate-beta-alanine ligase Ras PF00071.22 EAX92452.1 - 1.7e-48 164.2 0.1 2e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92452.1 - 1.8e-29 102.4 0.0 2.9e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92452.1 - 4.8e-11 42.4 0.0 6.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX92452.1 - 1.3e-06 28.4 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX92452.1 - 1.3e-05 25.1 0.0 0.068 13.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX92452.1 - 8.6e-05 22.0 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 EAX92452.1 - 0.00055 20.0 0.0 0.00099 19.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family SRPRB PF09439.10 EAX92452.1 - 0.0011 18.4 0.3 0.0024 17.3 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX92452.1 - 0.004 17.6 0.0 0.0062 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAX92452.1 - 0.0044 16.6 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 EAX92452.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 EAX92452.1 - 0.011 16.1 0.7 1.4 9.3 0.0 2.7 2 1 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 EAX92452.1 - 0.012 15.1 0.0 0.52 9.8 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EAX92452.1 - 0.033 14.4 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 EAX92454.1 - 4e-24 85.0 3.5 7.4e-10 39.3 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92454.1 - 4.8e-19 68.5 3.7 0.0023 18.5 0.1 6.5 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92454.1 - 2e-17 61.5 9.4 0.37 11.5 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX92454.1 - 5e-15 55.4 1.5 0.00066 19.9 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX92454.1 - 2.4e-08 34.1 6.2 3.3 8.3 0.0 7.9 7 2 1 8 8 8 2 Ankyrin repeat Chlam_PMP PF02415.17 EAX92455.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.6 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat V-SNARE PF05008.15 EAX92456.1 - 3.9e-14 52.8 2.4 3.9e-14 52.8 2.4 2.6 3 1 1 4 4 3 1 Vesicle transport v-SNARE protein N-terminus RIFIN PF02009.16 EAX92456.1 - 0.00059 19.8 0.9 0.00065 19.7 0.9 1.1 1 0 0 1 1 1 1 Rifin V-SNARE_C PF12352.8 EAX92456.1 - 0.0011 19.3 4.2 0.0011 19.3 4.2 1.9 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 EAX92456.1 - 0.0019 18.2 1.7 0.0036 17.2 0.7 2.1 2 0 0 2 2 1 1 SNARE domain Synaptobrevin PF00957.21 EAX92456.1 - 0.0049 16.6 0.7 0.0049 16.6 0.7 2.4 2 1 0 2 2 2 1 Synaptobrevin DUF5089 PF17002.5 EAX92456.1 - 0.0049 16.8 4.3 0.0049 16.8 4.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) DUF3671 PF12420.8 EAX92456.1 - 0.0062 16.6 0.9 0.042 13.9 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function Peptidase_S46 PF10459.9 EAX92456.1 - 0.035 12.8 3.3 0.04 12.6 3.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Laminin_II PF06009.12 EAX92456.1 - 0.14 12.2 10.4 0.39 10.7 0.8 2.5 1 1 0 2 2 2 0 Laminin Domain II RNase_H2-Ydr279 PF09468.10 EAX92456.1 - 0.15 12.2 4.8 0.28 11.3 4.8 1.4 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF1664 PF07889.12 EAX92456.1 - 0.16 12.0 7.0 0.4 10.7 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2207 PF09972.9 EAX92456.1 - 0.17 10.6 2.1 0.26 10.0 0.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CDC13_N PF16853.5 EAX92456.1 - 0.3 10.6 5.9 0.063 12.8 1.5 1.9 1 1 1 2 2 2 0 Cell division control protein 13 N-terminus ETRAMP PF09716.10 EAX92456.1 - 0.45 10.6 6.7 4.8 7.3 6.6 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Helo_like_N PF17111.5 EAX92456.1 - 0.64 9.4 6.3 1.2 8.5 0.9 2.5 1 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Syntaxin-6_N PF09177.11 EAX92456.1 - 0.64 10.6 8.5 4 8.0 1.8 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 EAX92456.1 - 0.86 9.1 8.7 1.1 8.8 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-ZPR1 PF03367.13 EAX92456.1 - 1.3 8.9 6.8 2.7 7.8 0.1 2.8 1 1 2 3 3 3 0 ZPR1 zinc-finger domain OmpH PF03938.14 EAX92456.1 - 3.8 7.8 12.6 1.4 9.3 9.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EAX92456.1 - 6.5 6.0 17.1 34 3.6 17.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCCH_4 PF18044.1 EAX92457.1 - 0.0044 16.8 5.1 0.0044 16.8 5.1 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAX92457.1 - 0.012 15.6 10.9 0.012 15.6 10.9 2.0 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 EAX92457.1 - 0.4 10.7 5.2 0.43 10.5 2.6 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3432 PF11914.8 EAX92458.1 - 0.14 12.4 2.0 0.24 11.7 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DUF1186 PF06685.11 EAX92459.1 - 0.073 12.5 0.7 0.22 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) MNSV_P7B PF06692.11 EAX92459.1 - 0.12 12.4 0.8 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Spidroin_N PF16763.5 EAX92460.1 - 0.029 14.4 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF563 PF04577.14 EAX92461.1 - 0.00022 21.4 0.9 0.0004 20.6 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LRR_adjacent PF08191.11 EAX92461.1 - 0.062 13.5 0.3 0.58 10.4 0.0 2.4 1 1 1 2 2 2 0 LRR adjacent DUF3781 PF12636.7 EAX92462.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX92463.1 - 0.11 11.5 0.2 0.11 11.5 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX92464.1 - 0.0086 16.1 6.0 0.013 15.5 6.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX92465.1 - 0.02 14.9 0.2 0.027 14.5 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Spore_coat_CotO PF14153.6 EAX92465.1 - 0.083 12.8 9.4 0.12 12.3 9.1 1.4 1 1 0 1 1 1 0 Spore coat protein CotO DUF2939 PF11159.8 EAX92466.1 - 0.034 14.5 0.3 0.046 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX92466.1 - 1.6 9.4 4.8 2.8 8.6 4.8 1.5 1 1 0 1 1 1 0 Homeodomain-like domain DUF1043 PF06295.12 EAX92467.1 - 0.047 13.7 0.2 0.067 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PapD_N PF00345.20 EAX92467.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX92467.1 - 0.072 13.1 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) KilA-N PF04383.13 EAX92468.1 - 2.4e-40 136.8 1.4 3.5e-40 136.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX92468.1 - 0.0068 16.6 0.4 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) KIP1 PF07765.12 EAX92468.1 - 6.3 7.0 9.4 19 5.5 0.7 3.4 2 1 1 3 3 3 0 KIP1-like protein Amidase02_C PF12123.8 EAX92469.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX92470.1 - 3.9e-33 114.9 3.2 7.3e-33 114.0 3.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX92471.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Glyco_transf_17 PF04724.13 EAX92472.1 - 0.0017 17.5 2.1 0.0022 17.1 2.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Ras PF00071.22 EAX92473.1 - 3.6e-52 176.2 0.1 4.3e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92473.1 - 2e-30 105.4 0.2 3.6e-30 104.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92473.1 - 2.3e-17 63.0 0.0 3.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX92473.1 - 4.8e-07 29.4 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX92473.1 - 3e-06 27.3 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EAX92473.1 - 3.5e-06 27.0 0.1 0.0013 18.6 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EAX92473.1 - 1.8e-05 24.4 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX92473.1 - 2.4e-05 23.9 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX92473.1 - 0.00023 21.1 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EAX92473.1 - 0.0005 20.3 0.6 0.0014 18.9 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX92473.1 - 0.0014 18.9 0.1 0.004 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAX92473.1 - 0.0067 16.6 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EAX92473.1 - 0.007 16.0 0.3 0.36 10.4 0.1 2.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EAX92473.1 - 0.014 15.9 0.2 0.074 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EAX92473.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 EAX92473.1 - 0.034 13.9 0.2 0.22 11.3 0.2 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EAX92473.1 - 0.066 13.5 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX92473.1 - 0.084 12.6 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX92473.1 - 0.11 13.1 0.3 0.16 12.5 0.3 1.5 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 EAX92473.1 - 0.12 12.1 0.4 0.25 11.1 0.1 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EAX92473.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EAX92473.1 - 0.2 11.2 0.6 1.6 8.2 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B CitMHS PF03600.16 EAX92474.1 - 2.5e-12 46.6 5.5 2.7e-12 46.5 5.5 1.0 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 EAX92474.1 - 1.6e-06 27.7 3.5 1.8e-06 27.6 3.5 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein ArsB PF02040.15 EAX92475.1 - 1.2e-16 61.1 12.1 1.4e-16 60.8 12.1 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 EAX92475.1 - 0.00014 21.2 25.2 0.00045 19.5 25.3 1.7 1 1 0 1 1 1 1 Citrate transporter YrhK PF14145.6 EAX92475.1 - 0.023 14.6 3.1 0.067 13.1 3.1 1.8 1 0 0 1 1 1 0 YrhK-like protein Gate PF07670.14 EAX92475.1 - 0.15 12.4 6.5 0.16 12.3 2.8 2.8 2 1 0 2 2 2 0 Nucleoside recognition DUF3827 PF12877.7 EAX92475.1 - 0.39 9.0 1.5 0.49 8.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4107 PF13389.6 EAX92476.1 - 4e-72 241.7 3.9 5.2e-72 241.3 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX92476.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta T5orf172 PF10544.9 EAX92477.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain Ank_4 PF13637.6 EAX92478.1 - 2.6e-35 120.4 7.7 7.6e-10 39.1 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX92478.1 - 3.2e-34 115.9 14.4 1.7e-08 34.5 0.1 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 EAX92478.1 - 6.7e-30 103.5 12.7 5.9e-15 55.6 4.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92478.1 - 1.2e-26 89.9 9.6 1.9e-05 24.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX92478.1 - 1.4e-20 73.0 3.8 1.2e-09 38.2 0.7 3.2 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX92478.1 - 0.00017 21.4 0.1 0.049 13.3 0.0 3.0 3 1 0 3 3 3 1 Colon cancer-associated protein Mic1-like MetallophosN PF16371.5 EAX92478.1 - 0.0053 17.0 0.0 2.2 8.6 0.0 3.3 1 1 2 3 3 3 1 N terminal of Calcineurin-like phosphoesterase DUF3718 PF12514.8 EAX92478.1 - 0.053 13.7 3.0 25 5.1 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAX92479.1 - 2.3e-12 47.2 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX92479.1 - 2.1e-09 37.4 1.3 7e-06 26.3 0.3 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX92479.1 - 6.5e-09 35.3 0.9 3.7e-06 26.9 0.3 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX92479.1 - 1.6e-08 35.0 0.4 2.2e-08 34.6 0.4 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92479.1 - 5.4e-06 26.6 0.2 5.7e-06 26.5 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX92480.1 - 3.6e-47 156.8 21.5 8.8e-08 32.3 0.4 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EAX92480.1 - 4.1e-47 158.0 25.3 1.9e-13 50.6 0.3 9.2 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92480.1 - 6.9e-46 154.8 29.1 9.6e-17 61.4 4.2 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92480.1 - 1.7e-38 130.2 29.3 2.2e-10 40.6 0.7 6.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92480.1 - 1.6e-36 120.1 19.7 1.3e-05 25.2 0.2 10.3 10 0 0 10 10 10 5 Ankyrin repeat DUF3447 PF11929.8 EAX92480.1 - 1e-35 121.5 8.7 1e-35 121.5 8.7 4.1 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAX92480.1 - 0.024 14.8 0.3 39 4.4 0.0 4.2 3 1 1 4 4 4 0 Centrosomal spindle body, CEP44 DUF3718 PF12514.8 EAX92480.1 - 0.029 14.5 7.5 17 5.6 0.2 5.4 2 1 3 5 5 5 0 Protein of unknown function (DUF3718) ERG2_Sigma1R PF04622.12 EAX92480.1 - 0.038 13.3 0.2 11 5.3 0.0 2.8 3 0 0 3 3 3 0 ERG2 and Sigma1 receptor like protein CCDC84 PF14968.6 EAX92480.1 - 2.4 7.7 7.8 9.1 5.8 0.1 2.3 1 1 1 2 2 2 0 Coiled coil protein 84 BRCT_2 PF16589.5 EAX92480.1 - 2.7 8.5 11.0 2.6 8.5 0.5 4.1 2 1 2 4 4 3 0 BRCT domain, a BRCA1 C-terminus domain DUF5460 PF17544.2 EAX92482.1 - 0.011 14.7 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5460) ResIII PF04851.15 EAX92483.1 - 2.4e-05 24.4 0.1 3e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92483.1 - 0.00037 20.3 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92483.1 - 0.0017 18.2 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX92483.1 - 0.0017 18.7 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX92483.1 - 0.0058 17.0 0.0 0.0082 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX92483.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein NIBRIN_BRCT_II PF16508.5 EAX92483.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein IstB_IS21 PF01695.17 EAX92483.1 - 0.069 12.9 0.0 0.084 12.6 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX92483.1 - 0.074 12.6 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX92483.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain GGDEF PF00990.21 EAX92484.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX92484.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX92484.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX92485.1 - 1.1e-64 216.7 6.7 1.2e-64 216.5 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX92486.1 - 2.1e-17 63.5 1.0 4.6e-05 23.9 0.0 5.5 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92486.1 - 4.1e-12 45.1 0.7 0.57 10.9 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EAX92486.1 - 8.7e-08 32.6 0.2 0.86 10.3 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92486.1 - 0.00015 22.0 0.1 0.24 11.8 0.0 4.8 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX92486.1 - 0.0015 18.9 2.2 12 6.5 0.1 6.2 5 1 0 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 EAX92486.1 - 0.026 14.5 0.0 0.026 14.5 0.0 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) B56 PF01603.20 EAX92487.1 - 8.5e-38 130.4 15.3 1.2e-37 130.0 15.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SMP_C2CD2L PF18696.1 EAX92487.1 - 0.011 15.6 0.8 0.02 14.7 0.1 1.7 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain DUF2684 PF10885.8 EAX92487.1 - 1 9.5 3.4 1.5 9.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2684) RYDR_ITPR PF01365.21 EAX92488.1 - 0.082 12.3 0.9 0.24 10.8 0.2 2.1 2 0 0 2 2 2 0 RIH domain Tai4 PF16695.5 EAX92488.1 - 0.1 13.1 0.5 16 6.1 0.4 2.9 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein DUF4065 PF13274.6 EAX92488.1 - 0.95 10.4 5.6 0.9 10.4 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) WD40 PF00400.32 EAX92489.1 - 9.7e-07 29.4 6.5 0.31 12.0 0.2 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EAX92489.1 - 0.021 13.4 0.0 0.045 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EAX92489.1 - 0.022 15.0 0.0 10 6.5 0.0 3.8 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain COQ9 PF08511.11 EAX92490.1 - 0.0054 16.5 0.1 0.086 12.6 0.0 2.2 2 0 0 2 2 2 1 COQ9 CAF1 PF04857.20 EAX92490.1 - 0.067 12.4 0.9 0.088 12.0 0.9 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease Ribosomal_S8e PF01201.22 EAX92491.1 - 1.1e-45 155.2 0.1 1.3e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF4106 PF13388.6 EAX92492.1 - 9.2e-185 614.8 26.7 5.1e-115 385.0 10.6 3.6 3 1 1 4 4 4 2 Protein of unknown function (DUF4106) IPK PF03770.16 EAX92493.1 - 5.2e-20 72.1 0.0 9.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Mo25 PF08569.11 EAX92494.1 - 1.4e-53 182.4 15.2 1.5e-53 182.3 15.2 1.0 1 0 0 1 1 1 1 Mo25-like HisKA PF00512.25 EAX92494.1 - 0.15 12.1 0.1 0.79 9.8 0.1 2.2 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain SIX1_SD PF16878.5 EAX92494.1 - 0.16 12.5 1.8 0.46 11.0 1.8 1.9 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain Orf78 PF06024.12 EAX92495.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Podoplanin PF05808.11 EAX92495.1 - 1.5e-05 25.2 1.0 5.1e-05 23.4 0.6 2.1 1 1 1 2 2 2 1 Podoplanin DUF4690 PF15756.5 EAX92495.1 - 0.00053 20.5 3.4 0.00053 20.5 3.4 2.6 1 1 0 2 2 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 EAX92495.1 - 0.001 19.0 1.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 EAX92495.1 - 0.0011 18.8 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ECSCR PF15820.5 EAX92495.1 - 0.0019 18.0 1.4 0.0058 16.4 1.4 1.8 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 EAX92495.1 - 0.01 16.7 0.1 0.026 15.4 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 EAX92495.1 - 0.016 15.0 2.2 0.036 13.8 2.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein RIFIN PF02009.16 EAX92495.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 Rifin CCSMST1 PF15013.6 EAX92495.1 - 0.029 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 CCSMST1 family DUF3827 PF12877.7 EAX92495.1 - 0.055 11.8 0.0 0.087 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sigma_reg_N PF13800.6 EAX92495.1 - 0.079 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5385 PF17359.2 EAX92495.1 - 0.1 12.1 0.8 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Stevor PF17410.2 EAX92495.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Mitofilin PF09731.9 EAX92495.1 - 0.14 11.0 8.4 0.19 10.5 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4519 PF15012.6 EAX92495.1 - 1.4 9.1 3.3 2.4 8.4 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SOG2 PF10428.9 EAX92495.1 - 1.6 7.8 5.6 2.2 7.4 5.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Amidinotransf PF02274.17 EAX92496.1 - 9.4e-52 176.2 0.0 1.2e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase PAD_porph PF04371.15 EAX92496.1 - 0.018 14.4 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Glycos_transf_1 PF00534.20 EAX92497.1 - 1.8e-05 24.3 0.3 4.7e-05 23.0 0.1 1.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAX92497.1 - 4.1e-05 24.0 0.0 8.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mob1_phocein PF03637.17 EAX92498.1 - 2e-72 242.7 0.0 2.3e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family LRR_4 PF12799.7 EAX92499.1 - 0.091 13.2 2.1 0.35 11.4 2.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF4108 PF13390.6 EAX92500.1 - 1.9e-53 180.2 7.8 2.2e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GH97_C PF14509.6 EAX92500.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Pox_A32 PF04665.12 EAX92502.1 - 5.8e-07 29.2 2.3 5.8e-07 29.2 2.3 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92502.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92502.1 - 4.1e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92502.1 - 0.00014 21.9 3.4 0.00029 20.9 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92502.1 - 0.00058 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92502.1 - 0.0014 18.5 0.7 0.0028 17.5 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92502.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92502.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92502.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX92502.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX92502.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX92502.1 - 0.22 11.8 4.4 4.4 7.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX92503.1 - 6e-41 138.8 0.4 1.5e-40 137.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Connexin PF00029.19 EAX92503.1 - 8.9 6.0 6.4 5.8 6.6 0.5 2.0 1 1 1 2 2 2 0 Connexin T5orf172 PF10544.9 EAX92504.1 - 7.6e-06 26.4 0.3 1.6e-05 25.4 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PTR PF12789.7 EAX92505.1 - 1.6e-14 53.7 24.5 3.5e-08 33.4 5.6 4.7 4 1 0 4 4 4 3 Phage tail repeat like Collagen PF01391.18 EAX92505.1 - 2.9e-07 30.1 13.1 5e-07 29.4 13.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX92505.1 - 0.083 13.0 0.0 0.083 13.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ILEI PF15711.5 EAX92505.1 - 0.12 12.9 0.2 0.49 10.9 0.2 2.1 1 0 0 1 1 1 0 Interleukin-like EMT inducer RecG_N PF17190.4 EAX92505.1 - 0.28 12.0 4.3 46 4.8 0.0 4.3 4 0 0 4 4 4 0 RecG N-terminal helical domain DUF4107 PF13389.6 EAX92508.1 - 2.6e-73 245.5 4.3 3.1e-73 245.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX92508.1 - 0.18 10.2 1.3 0.25 9.7 1.3 1.2 1 0 0 1 1 1 0 Lipoxygenase Hydrolase_like PF13242.6 EAX92510.1 - 1.2e-18 66.9 0.0 1.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 EAX92510.1 - 1.5e-05 24.7 0.2 2e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 EAX92510.1 - 0.00047 20.3 0.1 0.00061 19.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX92510.1 - 0.014 15.7 0.2 0.017 15.4 0.2 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase 5_nucleotid PF05761.14 EAX92510.1 - 0.096 11.6 0.0 0.096 11.6 0.0 1.0 1 0 0 1 1 1 0 5' nucleotidase family PrpR_N PF06506.11 EAX92510.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator Hydrolase_6 PF13344.6 EAX92511.1 - 6.6e-29 100.0 0.0 8.8e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UPF0180 PF03698.13 EAX92511.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0180) Hydrolase PF00702.26 EAX92511.1 - 0.0017 18.7 0.0 0.0036 17.6 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase RraB PF06877.11 EAX92511.1 - 0.022 15.5 0.0 0.059 14.1 0.0 1.7 2 0 0 2 2 2 0 Regulator of ribonuclease activity B HAD_2 PF13419.6 EAX92511.1 - 0.033 14.3 0.1 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase STAS PF01740.21 EAX92511.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 1 1 2 2 2 0 STAS domain Antimicrobial_7 PF08102.11 EAX92511.1 - 0.17 12.2 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Scorpion antimicrobial peptide SapB_1 PF05184.15 EAX92512.1 - 0.2 11.7 1.1 1.2 9.3 0.5 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 NRBF2 PF08961.10 EAX92512.1 - 0.71 9.5 10.5 0.23 11.1 6.3 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Casc1_N PF15927.5 EAX92512.1 - 0.93 9.1 17.9 0.087 12.5 5.1 3.3 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Cytochrom_B562 PF07361.11 EAX92512.1 - 2.7 8.7 10.9 5.3 7.7 2.0 3.2 3 0 0 3 3 3 0 Cytochrome b562 DUF2203 PF09969.9 EAX92512.1 - 7.8 7.2 8.1 7.9 7.2 2.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Herpes_UL52 PF03121.15 EAX92515.1 - 1e-07 31.8 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase RRM_5 PF13893.6 EAX92516.1 - 0.0044 16.6 0.1 0.035 13.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EAX92516.1 - 0.0061 16.3 0.2 0.016 15.0 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 EAX92516.1 - 0.018 14.7 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 MOZ/SAS family RRM_3 PF08777.11 EAX92516.1 - 0.088 12.9 0.7 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif zf-C3HC4_3 PF13920.6 EAX92517.1 - 7.5e-08 32.1 10.2 1.6e-07 31.0 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX92517.1 - 0.00088 19.1 9.6 0.002 18.0 9.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAX92517.1 - 0.0072 16.2 14.1 0.0072 16.2 14.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MF_alpha_N PF05436.11 EAX92517.1 - 0.064 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus zf-C3HC4_2 PF13923.6 EAX92517.1 - 0.11 12.3 11.1 0.35 10.8 11.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX92517.1 - 0.33 11.0 8.2 1.1 9.4 8.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Ank_2 PF12796.7 EAX92518.1 - 0.0014 19.2 0.6 0.015 15.9 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) COMMD1_N PF17221.3 EAX92518.1 - 0.074 13.4 1.6 1.2 9.5 0.1 3.4 3 0 0 3 3 3 0 COMMD1 N-terminal domain RRM_5 PF13893.6 EAX92518.1 - 0.25 10.9 1.2 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reticulon PF02453.17 EAX92519.1 - 0.0077 16.2 10.5 0.56 10.2 11.4 2.3 1 1 1 2 2 2 2 Reticulon MukE PF04288.13 EAX92519.1 - 0.23 10.4 0.3 0.36 9.7 0.3 1.2 1 0 0 1 1 1 0 MukE-like family Herpes_U26 PF07402.11 EAX92520.1 - 0.29 10.7 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 Human herpesvirus U26 protein DUF3447 PF11929.8 EAX92521.1 - 3.9e-38 129.2 5.3 3.9e-38 129.2 5.3 3.6 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX92521.1 - 1.3e-35 121.3 15.1 3.4e-12 46.6 0.6 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX92521.1 - 2e-34 116.5 11.7 1.3e-09 38.1 0.6 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX92521.1 - 3.1e-33 114.2 12.8 2.9e-18 66.2 4.6 4.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92521.1 - 8.4e-33 112.0 18.8 3e-12 46.5 0.8 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92521.1 - 1.1e-28 96.1 12.9 1.6e-07 31.0 0.2 7.3 7 0 0 7 7 7 4 Ankyrin repeat MetallophosN PF16371.5 EAX92521.1 - 0.00011 22.4 0.5 0.53 10.6 0.0 3.6 2 1 2 4 4 4 2 N terminal of Calcineurin-like phosphoesterase AAR2 PF05282.11 EAX92522.1 - 0.28 10.6 1.5 0.34 10.3 1.5 1.1 1 0 0 1 1 1 0 AAR2 protein Actin PF00022.19 EAX92523.1 - 3.1e-84 283.0 0.2 3.5e-66 223.5 0.1 3.1 2 1 0 2 2 2 2 Actin LacAB_rpiB PF02502.18 EAX92524.1 - 2.1e-59 199.5 1.2 2.4e-59 199.3 1.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Beta_helix PF13229.6 EAX92526.1 - 1.4e-11 44.5 25.7 4.2e-08 33.2 5.9 4.6 4 2 0 5 5 5 2 Right handed beta helix region NosD PF05048.13 EAX92526.1 - 0.0016 17.7 17.9 0.0016 17.7 17.9 3.8 4 1 1 5 5 5 2 Periplasmic copper-binding protein (NosD) DUF5123 PF17161.4 EAX92526.1 - 0.49 11.5 14.6 0.6 11.2 0.7 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5123) Collagen_bind_2 PF12904.7 EAX92527.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Fib_alpha PF08702.10 EAX92528.1 - 0.89 9.7 4.8 0.63 10.2 1.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AIG1 PF04548.16 EAX92529.1 - 3.2e-15 56.0 0.0 6.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EAX92529.1 - 3.3e-05 23.9 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX92529.1 - 0.012 15.5 0.1 0.047 13.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 EAX92529.1 - 0.023 14.9 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gly_rich PF12810.7 EAX92530.1 - 3.1e-56 191.0 30.7 3.8e-56 190.7 30.7 1.1 1 0 0 1 1 1 1 Glycine rich protein Vps51 PF08700.11 EAX92531.1 - 3.3e-18 65.6 1.7 3.3e-18 65.6 1.7 2.8 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 EAX92531.1 - 6.2e-12 45.7 6.9 6.2e-12 45.7 6.9 3.3 3 1 0 3 3 3 1 Exocyst complex component Sec5 Dor1 PF04124.12 EAX92531.1 - 1.1e-07 30.9 7.3 1.1e-07 30.9 7.3 3.0 4 1 0 4 4 4 1 Dor1-like family Vps54_N PF10475.9 EAX92531.1 - 3.8e-05 23.1 8.2 3.8e-05 23.1 8.2 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex FlaC_arch PF05377.11 EAX92531.1 - 0.063 13.7 0.7 0.063 13.7 0.7 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SEO_C PF14577.6 EAX92531.1 - 0.57 9.6 5.5 0.83 9.0 0.3 2.9 3 0 0 3 3 3 0 Sieve element occlusion C-terminus MCPsignal PF00015.21 EAX92531.1 - 2.5 7.9 8.1 1.7 8.5 0.5 3.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG5 PF10392.9 EAX92531.1 - 3.3 7.9 15.1 0.31 11.2 2.7 3.4 4 0 0 4 4 4 0 Golgi transport complex subunit 5 COG2 PF06148.11 EAX92531.1 - 3.5 7.7 9.2 0.1 12.7 0.7 2.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 FAR1 PF03101.15 EAX92532.1 - 0.037 14.7 0.1 0.073 13.8 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3839 PF12943.7 EAX92535.1 - 6.1e-156 517.0 13.4 7.7e-156 516.7 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92535.1 - 0.068 13.0 0.8 0.29 11.0 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX92535.1 - 0.071 13.4 0.5 1.4 9.2 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain MitMem_reg PF13012.6 EAX92535.1 - 0.11 12.9 0.5 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX92535.1 - 1.3 9.5 7.6 2.1 8.9 0.8 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX92536.1 - 2.2e-41 140.2 0.6 6e-41 138.8 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX92536.1 - 0.011 15.0 0.2 0.038 13.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase RPAP3_C PF13877.6 EAX92536.1 - 0.19 12.3 2.1 1.9 9.1 0.4 2.5 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Trypan_PARP PF05887.11 EAX92537.1 - 0.11 12.5 6.9 0.15 12.1 6.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX92538.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92538.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX92539.1 - 0.034 14.6 0.5 0.041 14.3 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92539.1 - 0.099 11.6 0.1 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain HTH_29 PF13551.6 EAX92541.1 - 0.035 14.1 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EAX92541.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 Transposase Peptidase_M8 PF01457.16 EAX92542.1 - 2.9e-24 85.7 0.0 2.9e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Leishmanolysin Mem_trans PF03547.18 EAX92542.1 - 0.0021 16.5 0.3 0.0031 16.0 0.3 1.2 1 0 0 1 1 1 1 Membrane transport protein OSTbeta PF15048.6 EAX92542.1 - 0.081 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4915 PF16261.5 EAX92542.1 - 0.1 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) FAM176 PF14851.6 EAX92542.1 - 0.13 11.9 2.2 0.26 10.9 2.2 1.5 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.15 EAX92542.1 - 0.17 12.5 0.2 0.65 10.6 0.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Zip PF02535.22 EAX92542.1 - 0.78 8.9 3.5 1.4 8.0 3.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 EAX92542.1 - 1.8 9.5 6.8 8.7 7.4 6.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Conotoxin PF02950.17 EAX92542.1 - 6.3 7.9 6.3 2.2 9.3 0.1 2.8 1 1 1 2 2 2 0 Conotoxin TPR_MLP1_2 PF07926.12 EAX92543.1 - 0.001 19.1 18.0 0.001 19.1 18.0 11.3 6 3 6 13 13 13 4 TPR/MLP1/MLP2-like protein DUF4625 PF15418.6 EAX92545.1 - 6.3e-05 23.2 18.2 0.072 13.3 0.1 7.5 8 0 0 8 8 8 2 Domain of unknown function (DUF4625) Big_3_4 PF13754.6 EAX92545.1 - 0.078 12.7 5.5 6.3 6.6 0.1 4.5 4 1 0 4 4 4 0 Domain of unknown function Big_7 PF17957.1 EAX92545.1 - 0.099 13.4 4.1 40 5.1 0.0 5.6 6 0 0 6 6 6 0 Bacterial Ig domain DDR PF08841.10 EAX92547.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX92547.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Methyltransf_PK PF05891.12 EAX92549.1 - 1.5e-50 171.8 0.1 1.7e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EAX92549.1 - 1.7e-08 34.0 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EAX92549.1 - 6e-05 23.7 0.0 9.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX92549.1 - 0.0014 19.2 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EAX92549.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DUF1015 PF06245.11 EAX92550.1 - 3.1e-106 355.6 0.0 3.5e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) PepSY_TM PF03929.16 EAX92551.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region RNaseH_C PF09293.10 EAX92551.1 - 0.16 12.3 0.2 0.29 11.5 0.2 1.4 1 0 0 1 1 1 0 T4 RNase H, C terminal Pkinase PF00069.25 EAX92552.1 - 1.1e-29 103.6 0.1 1.7e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92552.1 - 1.8e-16 60.2 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX92552.1 - 2e-08 33.5 0.1 2.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX92552.1 - 0.023 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX92552.1 - 0.023 14.6 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family AP4E_app_platf PF14807.6 EAX92552.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Bromodomain PF00439.25 EAX92553.1 - 0.00054 20.0 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain DUF919 PF06034.11 EAX92553.1 - 0.042 13.7 1.6 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DSPc PF00782.20 EAX92553.1 - 0.057 13.2 0.3 0.42 10.4 0.1 2.4 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain DUF3938 PF13074.6 EAX92554.1 - 0.094 13.0 2.4 6.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF3839 PF12943.7 EAX92555.1 - 4.2e-07 29.7 1.4 6.8e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX92556.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92556.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92556.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92556.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92556.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92556.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92556.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92556.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92556.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX92556.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX92556.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX92556.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TAF8_C PF10406.9 EAX92557.1 - 8 7.1 8.2 4.9 7.8 6.1 1.8 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term DUF4108 PF13390.6 EAX92558.1 - 2e-62 209.4 8.4 2.2e-62 209.2 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) MCPsignal PF00015.21 EAX92560.1 - 0.00021 21.1 1.2 0.00021 21.1 1.2 6.6 5 2 3 8 8 8 3 Methyl-accepting chemotaxis protein (MCP) signalling domain PALP PF00291.25 EAX92561.1 - 6e-76 255.7 1.0 8.1e-76 255.2 1.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsA PF14450.6 EAX92561.1 - 0.1 13.1 0.1 0.35 11.3 0.1 2.0 2 1 0 2 2 2 0 Cell division protein FtsA DUF4107 PF13389.6 EAX92562.1 - 2.6e-30 105.7 1.7 3.8e-30 105.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) GPS2_interact PF15784.5 EAX92563.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX92564.1 - 0.15 12.0 8.9 0.24 11.4 8.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX92564.1 - 5 4.7 14.4 6.6 4.3 14.4 1.2 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX92564.1 - 9.9 6.6 8.2 15 6.1 8.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX92565.1 - 4.3e-153 507.7 14.3 5.3e-153 507.4 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92565.1 - 0.0066 16.3 0.9 0.024 14.5 0.2 2.0 1 1 1 2 2 2 1 Nucleotidyltransferase KELK PF15796.5 EAX92565.1 - 0.27 11.7 5.5 1.9 9.0 0.7 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX92565.1 - 0.56 10.8 5.4 0.23 12.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) FliJ PF02050.16 EAX92567.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein WD40 PF00400.32 EAX92568.1 - 3.3e-28 97.3 11.1 9.3e-07 29.5 0.0 7.2 6 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX92568.1 - 2.3e-15 56.7 0.0 0.00073 19.8 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX92568.1 - 5.7e-05 22.2 2.3 3.9 6.3 0.1 4.2 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAX92568.1 - 0.0013 18.6 1.5 12 5.9 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 EAX92568.1 - 0.0025 16.2 0.4 0.2 9.9 0.0 2.4 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz SGL PF08450.12 EAX92568.1 - 0.013 15.1 0.1 0.11 12.1 0.0 2.3 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 EAX92568.1 - 0.014 15.9 0.0 4.6 7.9 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain DUF4988 PF16378.5 EAX92568.1 - 0.026 14.2 1.9 0.44 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF563 PF04577.14 EAX92569.1 - 4e-16 59.8 0.0 5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 EAX92570.1 - 5.2e-20 72.5 0.0 7.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Metallophos PF00149.28 EAX92572.1 - 1.1e-13 52.2 0.3 1.5e-13 51.8 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX92572.1 - 0.00034 20.9 0.1 0.00048 20.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EAX92572.1 - 0.0036 17.7 0.1 0.011 16.2 0.1 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF563 PF04577.14 EAX92573.1 - 8.9e-30 104.4 0.1 1.4e-29 103.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MULE PF10551.9 EAX92574.1 - 3e-10 40.4 0.2 8.2e-10 39.0 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX92574.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Trypan_PARP PF05887.11 EAX92575.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX92576.1 - 0.019 14.9 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX92577.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX92577.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX92577.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX92577.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX92578.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX92578.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX92578.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX92580.1 - 3.6e-10 39.7 0.1 4.1e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain WH1 PF00568.23 EAX92581.1 - 4e-07 30.0 1.0 8.2e-07 29.0 1.0 1.5 1 0 0 1 1 1 1 WH1 domain PFK PF00365.20 EAX92582.1 - 2.3e-74 250.3 0.8 2.9e-74 250.0 0.8 1.1 1 0 0 1 1 1 1 Phosphofructokinase YAcAr PF10686.9 EAX92582.1 - 0.0043 17.0 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 YspA, cpYpsA-related SLOG family TMEM154 PF15102.6 EAX92584.1 - 0.017 15.0 0.8 0.035 14.0 0.3 1.7 1 1 0 1 1 1 0 TMEM154 protein family TPPK_C PF12555.8 EAX92584.1 - 0.06 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal EVC2_like PF12297.8 EAX92584.1 - 0.068 11.8 0.0 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein HRG PF16954.5 EAX92584.1 - 0.094 13.1 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene FixH PF05751.11 EAX92584.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 FixH EphA2_TM PF14575.6 EAX92584.1 - 0.14 13.0 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 EAX92585.1 - 3.3e-71 239.8 0.0 4.8e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92585.1 - 1.9e-40 138.8 0.0 2.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EAX92585.1 - 2.4e-18 66.1 0.1 2.4e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EAX92585.1 - 1.2e-09 37.9 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAX92585.1 - 2.8e-07 29.7 0.0 3.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX92585.1 - 0.03 14.2 0.0 0.71 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ATP-synt_S1 PF05827.12 EAX92586.1 - 0.0056 16.5 0.1 0.0069 16.2 0.1 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SecE PF00584.20 EAX92586.1 - 0.017 15.0 1.0 0.029 14.3 1.0 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2062 PF09835.9 EAX92586.1 - 0.045 13.6 1.0 0.052 13.4 0.7 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2207 PF09972.9 EAX92586.1 - 0.17 10.6 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HECT PF00632.25 EAX92587.1 - 1e-79 268.3 1.3 5e-79 266.0 0.0 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EAX92587.1 - 4.1e-13 49.4 0.8 4.1e-13 49.4 0.8 1.9 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A AAA_31 PF13614.6 EAX92587.1 - 0.29 11.0 1.7 2.6 7.9 0.7 2.3 2 0 0 2 2 2 0 AAA domain Gelsolin PF00626.22 EAX92588.1 - 2.5e-11 43.3 1.0 0.00054 19.8 0.1 4.0 3 1 1 4 4 4 3 Gelsolin repeat Bromodomain PF00439.25 EAX92589.1 - 5.4e-20 71.3 1.1 6.1e-19 67.9 0.1 2.4 2 0 0 2 2 2 1 Bromodomain Mif2_N PF15624.6 EAX92591.1 - 0.35 11.6 4.7 0.59 10.9 4.7 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Bromodomain PF00439.25 EAX92592.1 - 9.8e-22 76.8 1.4 1.7e-21 76.1 0.3 1.9 2 0 0 2 2 2 1 Bromodomain tRNA_synthFbeta PF17759.1 EAX92593.1 - 2.6e-35 121.8 0.0 4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EAX92593.1 - 8.5e-26 90.0 0.2 3.3e-25 88.1 0.1 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 EAX92593.1 - 1.5e-21 76.5 0.1 8.3e-16 58.0 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 EAX92593.1 - 2.7e-18 66.2 0.0 5.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.20 EAX92593.1 - 0.0057 16.2 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) IalB PF06776.12 EAX92593.1 - 0.12 12.5 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Invasion associated locus B (IalB) protein PSP PF04046.16 EAX92595.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92596.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX92597.1 - 0.022 15.2 0.6 0.045 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX92598.1 - 1.3e-40 137.2 28.3 2.9e-23 81.7 7.3 5.8 6 1 1 7 7 7 3 Phage tail repeat like DUF4116 PF13475.6 EAX92598.1 - 0.091 12.5 0.6 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) CppA_C PF14507.6 EAX92598.1 - 0.24 12.1 1.5 4.4 8.1 0.4 3.2 2 0 0 2 2 2 0 CppA C-terminal DUF4795 PF16043.5 EAX92598.1 - 2.8 7.5 25.9 1.8e+03 -1.7 25.9 3.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX92598.1 - 3.8 7.6 19.4 2.9 8.0 3.3 4.5 2 1 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) DUF4107 PF13389.6 EAX92601.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX92602.1 - 0.0035 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase CEP63 PF17045.5 EAX92603.1 - 0.00097 19.1 12.4 0.00097 19.1 12.4 4.1 2 2 1 3 3 3 2 Centrosomal protein of 63 kDa Latarcin PF10279.9 EAX92603.1 - 0.073 13.5 0.3 0.073 13.5 0.3 4.3 3 1 0 3 3 3 0 Latarcin precursor Pox_P4B PF03292.14 EAX92604.1 - 0.13 10.5 0.9 0.14 10.4 0.9 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF2730 PF10805.8 EAX92604.1 - 0.41 10.8 4.7 0.78 9.9 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 EAX92604.1 - 2.5 7.6 8.6 2.9 7.4 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TarH PF02203.15 EAX92605.1 - 0.16 11.9 0.1 0.51 10.2 0.1 1.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue Meckelin PF09773.9 EAX92606.1 - 3.6e-154 515.0 15.9 4.4e-154 514.7 15.9 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Nup96 PF12110.8 EAX92607.1 - 6.1e-08 32.1 2.0 2.4e-06 26.9 2.0 2.7 1 1 0 1 1 1 1 Nuclear protein 96 120_Rick_ant PF12574.8 EAX92607.1 - 0.068 12.4 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen Sds3 PF08598.11 EAX92608.1 - 0.00038 20.5 7.3 0.00053 20.1 6.9 1.3 1 1 0 1 1 1 1 Sds3-like Atg14 PF10186.9 EAX92608.1 - 0.00064 18.9 3.0 0.00084 18.5 3.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PCI PF01399.27 EAX92608.1 - 0.013 16.0 1.6 0.074 13.6 1.6 2.0 1 1 0 1 1 1 0 PCI domain DUF3584 PF12128.8 EAX92608.1 - 0.015 12.9 4.2 0.018 12.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC84 PF14968.6 EAX92608.1 - 0.048 13.3 1.2 0.053 13.1 1.2 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Golgin_A5 PF09787.9 EAX92608.1 - 0.061 12.8 6.5 0.091 12.2 6.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1640 PF07798.11 EAX92608.1 - 0.14 12.1 4.9 0.22 11.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) OmpH PF03938.14 EAX92608.1 - 0.28 11.5 8.1 0.71 10.2 8.1 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Exo84_C PF16528.5 EAX92609.1 - 3e-09 37.0 1.0 6.4e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal COG2 PF06148.11 EAX92609.1 - 0.067 13.3 0.1 0.29 11.2 0.1 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4751 PF15942.5 EAX92609.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) DUF5454 PF17535.2 EAX92609.1 - 2.3 7.5 6.5 7.4 5.9 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5454) Ank_2 PF12796.7 EAX92610.1 - 1.7e-09 38.1 0.3 0.00035 21.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92610.1 - 7.2e-06 26.0 0.2 6 7.8 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat DUF3447 PF11929.8 EAX92610.1 - 1.1e-05 25.3 4.1 1.1e-05 25.3 4.1 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX92610.1 - 4.5e-05 23.9 0.8 2.6 8.7 0.1 4.3 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92610.1 - 0.0011 19.3 0.2 4.6 7.7 0.0 3.9 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX92610.1 - 0.003 17.9 0.0 3.8 8.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Gly_rich PF12810.7 EAX92611.1 - 5.3e-10 39.6 26.1 6.7e-10 39.3 26.1 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF5642 PF18702.1 EAX92611.1 - 0.42 10.4 0.7 0.6 9.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) Cpn60_TCP1 PF00118.24 EAX92612.1 - 1e-146 489.4 10.6 1.2e-146 489.2 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4107 PF13389.6 EAX92614.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX92614.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX92615.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Myb_DNA-binding PF00249.31 EAX92617.1 - 1.6e-28 98.7 0.9 5.5e-14 52.1 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92617.1 - 7e-21 74.2 3.1 3.1e-12 46.6 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX92617.1 - 2.6e-05 24.0 0.7 9.8e-05 22.2 0.1 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX92617.1 - 0.0016 18.6 0.3 0.0025 17.9 0.3 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX92617.1 - 0.0026 17.7 0.0 2.7 8.0 0.0 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX92617.1 - 0.24 11.8 2.1 1.6 9.1 0.1 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Kelch_4 PF13418.6 EAX92618.1 - 1.4e-24 85.8 1.7 7.2e-09 35.5 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EAX92618.1 - 1.6e-19 69.7 4.4 6.7e-08 32.6 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX92618.1 - 2.8e-16 59.1 6.4 1.6e-05 25.0 0.1 5.7 4 1 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EAX92618.1 - 9.8e-10 38.2 6.1 0.0065 16.4 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EAX92618.1 - 4.4e-09 35.8 10.6 0.0012 18.4 0.1 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAX92618.1 - 5.7e-08 32.4 6.7 1.4 9.0 0.1 5.5 5 0 0 5 5 5 4 Kelch motif DUF257 PF03192.13 EAX92620.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Sec2p PF06428.11 EAX92620.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p GPS2_interact PF15784.5 EAX92621.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX92621.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX92622.1 - 0.095 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX92623.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX92623.1 - 0.12 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family MULE PF10551.9 EAX92624.1 - 3.9e-13 49.6 0.1 8.3e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX92624.1 - 0.2 11.4 4.6 0.27 10.9 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Pox_Ag35 PF03286.14 EAX92624.1 - 1.5 8.6 5.4 2.5 7.8 5.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ATP13 PF12921.7 EAX92625.1 - 0.41 10.5 4.6 1.2 9.0 0.6 3.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression UNC45-central PF11701.8 EAX92625.1 - 1 9.3 6.8 3.8 7.4 0.9 3.4 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central Ank_2 PF12796.7 EAX92626.1 - 1.3e-14 54.6 3.9 7e-09 36.2 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92626.1 - 2.2e-12 47.2 2.2 1.4e-05 25.6 0.2 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92626.1 - 8.5e-12 44.2 1.3 0.0086 16.5 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX92626.1 - 4.3e-07 30.1 0.9 0.042 14.3 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX92626.1 - 6.1e-07 29.6 2.6 0.0072 16.6 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Toprim_3 PF13362.6 EAX92626.1 - 0.023 15.0 0.3 1.1 9.7 0.1 2.2 1 1 1 2 2 2 0 Toprim domain Mqo PF06039.15 EAX92626.1 - 0.049 12.2 0.1 0.066 11.8 0.1 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ras PF00071.22 EAX92627.1 - 2.3e-13 50.0 0.0 3.1e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92627.1 - 1.2e-10 41.7 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX92627.1 - 3.4e-07 30.3 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX92627.1 - 0.00079 19.0 0.0 0.63 9.6 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EAX92627.1 - 0.003 17.0 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family IIGP PF05049.13 EAX92627.1 - 0.0039 16.3 0.0 0.0051 15.9 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.6 EAX92627.1 - 0.0045 17.0 0.1 0.0082 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EAX92627.1 - 0.0065 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 EAX92627.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.12 EAX92627.1 - 0.0083 15.5 0.0 0.0097 15.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EAX92627.1 - 0.0093 15.7 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EAX92627.1 - 0.019 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.23 EAX92627.1 - 0.032 14.3 0.0 0.55 10.3 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Myb_DNA-binding PF00249.31 EAX92628.1 - 2.7e-34 117.1 0.6 1.6e-16 60.2 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX92628.1 - 8.5e-25 86.8 0.9 3e-17 62.6 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX92628.1 - 2.7e-06 27.4 0.1 0.011 15.8 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX92628.1 - 6.9e-06 26.2 0.3 0.00021 21.4 0.1 2.4 1 1 1 2 2 2 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX92628.1 - 7.6e-06 25.7 0.6 0.00027 20.8 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX92628.1 - 0.013 15.7 0.1 0.057 13.6 0.0 1.9 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 EcpB_C PF18649.1 EAX92628.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 EcpB C-terminal domain Myb_DNA-bind_4 PF13837.6 EAX92628.1 - 0.2 12.1 5.2 3 8.3 0.6 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_C1 PF00112.23 EAX92631.1 - 2.1e-09 37.8 0.1 5.9e-09 36.3 0.1 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 EAX92631.1 - 0.027 14.3 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C1 propeptide ALG11_N PF15924.5 EAX92632.1 - 3.4e-70 236.4 0.9 5.7e-70 235.6 0.9 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EAX92632.1 - 5.1e-17 61.9 0.0 1.1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAX92632.1 - 7.3e-07 29.7 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAX92632.1 - 0.00092 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF2919 PF11143.8 EAX92632.1 - 0.19 12.1 1.5 0.44 10.9 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Phage_holin_6_1 PF09682.10 EAX92633.1 - 0.34 11.3 5.5 0.93 9.9 1.8 2.5 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4061 PF13270.6 EAX92633.1 - 0.63 10.4 3.5 1.9 8.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) Tht1 PF04163.12 EAX92633.1 - 0.98 8.1 5.4 0.98 8.1 4.5 1.4 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein ArAE_2_N PF10337.9 EAX92633.1 - 1.2 8.1 3.4 1.4 7.9 3.4 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal AcylCoA_dehyd_C PF12186.8 EAX92633.1 - 1.4 9.0 7.5 9.3 6.4 2.2 3.0 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal FliD_N PF02465.18 EAX92633.1 - 4.8 7.9 9.1 5.2 7.8 3.3 3.0 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Adap_comp_sub PF00928.21 EAX92634.1 - 6e-81 271.7 0.0 7.7e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAX92634.1 - 2.5e-06 27.5 0.2 4.4e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Regnase_1_C PF18561.1 EAX92634.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain TMP PF05017.14 EAX92636.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX92637.1 - 0.028 14.9 0.6 0.076 13.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4107 PF13389.6 EAX92639.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX92639.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase Ras PF00071.22 EAX92640.1 - 9.8e-54 181.3 0.1 1.1e-53 181.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92640.1 - 1.4e-32 112.5 0.0 1.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92640.1 - 1.7e-13 50.4 0.0 1.9e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX92640.1 - 2.8e-05 24.1 1.3 0.098 12.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX92640.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX92640.1 - 0.0034 17.5 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EAX92640.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAX92640.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EAX92640.1 - 0.032 13.6 0.0 0.087 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EAX92640.1 - 0.04 13.6 0.1 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAX92640.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EAX92640.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ank_2 PF12796.7 EAX92641.1 - 5.7e-26 90.9 1.2 8.4e-13 48.7 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92641.1 - 1.4e-25 89.0 1.5 6.4e-11 42.3 0.2 6.4 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92641.1 - 5.4e-22 77.9 0.0 7e-08 32.9 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92641.1 - 8.9e-19 65.6 0.1 3.4e-06 27.0 0.0 7.1 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 EAX92641.1 - 9.7e-15 54.3 0.0 2.2e-08 34.2 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX92641.1 - 1.9e-08 34.1 0.0 3e-07 30.3 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DUF2496 PF10689.9 EAX92641.1 - 0.05 13.4 1.8 0.13 12.0 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2496) SF3b10 PF07189.11 EAX92643.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) Anthrax-tox_M PF09156.10 EAX92643.1 - 0.071 12.4 0.0 0.078 12.3 0.0 1.0 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Gly_rich PF12810.7 EAX92644.1 - 1.4e-57 195.4 34.7 1.7e-57 195.1 34.7 1.1 1 0 0 1 1 1 1 Glycine rich protein zf-C3HC4_3 PF13920.6 EAX92645.1 - 3.9e-09 36.2 12.9 9e-09 35.1 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX92645.1 - 2.9e-06 27.0 13.1 6.3e-06 25.9 13.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAX92645.1 - 6.1e-06 26.2 8.1 1.6e-05 24.8 5.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX92645.1 - 0.00016 21.6 13.8 0.00082 19.3 14.1 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAX92645.1 - 0.00026 20.8 13.5 0.00058 19.6 13.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX92645.1 - 0.00051 20.3 14.4 0.00051 20.3 14.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAX92645.1 - 0.0075 16.1 13.9 0.023 14.6 13.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAX92645.1 - 0.0093 16.2 8.4 0.034 14.4 8.4 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EAX92645.1 - 0.015 15.2 5.5 0.015 15.2 5.5 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein DUF1664 PF07889.12 EAX92645.1 - 1.2 9.1 16.5 29 4.7 0.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4_4 PF15227.6 EAX92645.1 - 1.3 9.2 9.6 8.7 6.6 9.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PIN_2 PF10130.9 EAX92645.1 - 4.9 7.4 7.6 11 6.3 0.1 3.9 3 2 0 4 4 4 0 PIN domain Sds3 PF08598.11 EAX92645.1 - 5.1 7.0 15.3 1.6 8.6 6.4 3.0 2 1 1 3 3 3 0 Sds3-like L31 PF09784.9 EAX92645.1 - 6.4 7.3 7.2 5.3 7.5 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 HisKA_2 PF07568.12 EAX92645.1 - 7.2 6.8 9.5 1.1 9.4 0.3 4.0 4 0 0 4 4 4 0 Histidine kinase AnfG_VnfG PF03139.15 EAX92646.1 - 0.053 13.6 2.1 0.076 13.1 1.5 1.5 1 1 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit DUF5320 PF17253.2 EAX92646.1 - 1 10.5 2.7 0.81 10.8 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) F5_F8_type_C PF00754.25 EAX92647.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain Ubiquitin_4 PF18036.1 EAX92648.1 - 0.021 14.9 0.6 0.075 13.1 0.4 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain LRR_5 PF13306.6 EAX92649.1 - 5e-55 184.9 25.6 3.4e-24 85.2 0.1 4.7 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92649.1 - 7.6e-06 25.6 0.1 0.011 15.4 0.0 4.9 5 1 0 5 5 5 1 Leucine rich repeat MGC-24 PF05283.11 EAX92649.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FNIP PF05725.12 EAX92649.1 - 0.023 14.8 1.5 0.38 11.0 0.0 3.8 4 0 0 4 4 4 0 FNIP Repeat PADR1 PF08063.12 EAX92649.1 - 0.29 11.0 2.1 0.83 9.5 0.2 2.4 2 0 0 2 2 2 0 PADR1 (NUC008) domain LRR_4 PF12799.7 EAX92650.1 - 1.3e-12 47.7 1.3 8.9e-07 29.1 1.0 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX92650.1 - 1.4e-11 44.2 1.5 2.3e-11 43.5 1.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAX92650.1 - 6.1e-05 22.7 0.2 0.022 14.5 0.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat DUF5590 PF17881.1 EAX92650.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) LRR_1 PF00560.33 EAX92650.1 - 0.2 12.3 0.4 6.2 7.8 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_5 PF13306.6 EAX92651.1 - 9.2e-83 274.6 17.8 2.4e-25 88.9 0.4 4.9 1 1 4 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92651.1 - 6.1e-08 32.3 0.3 0.07 12.9 0.0 4.6 5 0 0 5 5 5 2 Leucine rich repeat FNIP PF05725.12 EAX92651.1 - 0.00071 19.7 0.3 11 6.2 0.0 4.5 3 1 0 3 3 3 2 FNIP Repeat Plasmodium_Vir PF05795.11 EAX92651.1 - 0.0074 15.7 1.6 0.011 15.2 1.6 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein MGC-24 PF05283.11 EAX92651.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pneumo_M2 PF07380.11 EAX92652.1 - 0.3 11.4 0.1 0.3 11.4 0.1 3.0 3 0 0 3 3 3 0 Pneumovirus M2 protein DUF1765 PF08578.10 EAX92652.1 - 1.9 9.0 7.9 0.94 10.0 1.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1765) BTB PF00651.31 EAX92653.1 - 4.5e-12 46.2 0.3 7.3e-12 45.5 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C3Hc3H PF13891.6 EAX92654.1 - 2.9e-08 33.9 9.7 5.9e-08 33.0 5.5 2.4 2 0 0 2 2 2 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 EAX92654.1 - 0.11 12.3 3.3 2.5 7.9 0.7 2.8 2 1 0 2 2 2 0 CCCH zinc finger in TRM13 protein DUF3885 PF13021.6 EAX92654.1 - 0.27 11.3 1.9 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) zf-AN1 PF01428.16 EAX92654.1 - 0.83 9.9 7.1 9.1 6.5 0.4 3.5 2 1 1 3 3 3 0 AN1-like Zinc finger PSP PF04046.16 EAX92655.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92656.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Dynamin_M PF01031.20 EAX92657.1 - 1.6e-86 290.1 0.1 3.7e-86 288.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EAX92657.1 - 1.6e-51 174.7 0.0 3.6e-51 173.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAX92657.1 - 1.8e-19 69.7 0.9 1.8e-19 69.7 0.9 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAX92657.1 - 3.6e-05 23.8 0.0 0.00014 21.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAX92657.1 - 0.04 13.3 0.1 3.6 6.8 0.0 2.6 2 0 0 2 2 2 0 AIG1 family PaRep2a PF07903.11 EAX92658.1 - 0.011 15.6 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 PaRep2a protein DUF349 PF03993.12 EAX92658.1 - 0.073 13.4 2.3 0.086 13.2 2.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Gly-zipper_Omp PF13488.6 EAX92660.1 - 0.0046 16.9 8.6 0.0077 16.2 8.6 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX92660.1 - 0.073 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX92660.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX92660.1 - 0.32 11.3 4.6 0.49 10.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX92660.1 - 0.85 9.8 5.1 1.4 9.0 5.1 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DnaJ_C PF01556.18 EAX92663.1 - 9.1e-39 132.9 0.2 1.2e-38 132.6 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX92663.1 - 1.1e-27 95.9 2.8 1.7e-27 95.3 2.8 1.2 1 0 0 1 1 1 1 DnaJ domain Menin PF05053.13 EAX92664.1 - 0.011 14.2 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Menin ZapB PF06005.12 EAX92665.1 - 7.8e-05 23.0 1.0 0.00013 22.3 1.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB Tektin PF03148.14 EAX92665.1 - 0.00035 19.4 0.3 0.00045 19.1 0.3 1.1 1 0 0 1 1 1 1 Tektin family DivIC PF04977.15 EAX92665.1 - 0.00061 19.5 1.0 0.0017 18.1 0.8 1.8 2 0 0 2 2 2 1 Septum formation initiator DUF5082 PF16888.5 EAX92665.1 - 0.00067 19.9 3.0 0.0014 18.9 3.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) EzrA PF06160.12 EAX92665.1 - 0.0023 16.2 2.2 0.0028 15.9 2.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4795 PF16043.5 EAX92665.1 - 0.0099 15.5 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF4140 PF13600.6 EAX92665.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GPS2_interact PF15784.5 EAX92665.1 - 0.022 15.2 0.7 0.04 14.3 0.7 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Spc19 PF08287.11 EAX92665.1 - 0.029 14.3 2.8 0.073 13.0 2.3 1.8 1 1 1 2 2 2 0 Spc19 DUF4250 PF14056.6 EAX92665.1 - 0.038 13.9 0.6 0.083 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) bZIP_2 PF07716.15 EAX92665.1 - 0.081 13.0 5.3 0.15 12.1 5.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper GSH_synthase PF03199.15 EAX92665.1 - 0.087 13.3 0.2 0.14 12.7 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase PI3K_P85_iSH2 PF16454.5 EAX92665.1 - 0.098 12.2 3.5 0.13 11.9 3.2 1.4 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain 5_nucleotid PF05761.14 EAX92665.1 - 0.11 11.4 1.0 0.14 11.0 1.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF465 PF04325.13 EAX92665.1 - 0.13 12.3 4.2 0.31 11.1 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Osmo_CC PF08946.10 EAX92665.1 - 0.18 12.1 2.3 0.35 11.1 1.5 1.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Spc24 PF08286.11 EAX92665.1 - 0.53 10.6 4.7 1.2 9.4 4.7 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Myc-LZ PF02344.15 EAX92665.1 - 0.83 9.8 7.8 1.5 9.0 7.8 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain Baculo_PEP_C PF04513.12 EAX92666.1 - 0.00071 19.6 19.4 0.0038 17.3 0.1 3.6 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EAX92666.1 - 0.0048 16.8 0.2 0.036 14.0 0.0 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain COMP PF11598.8 EAX92666.1 - 0.012 16.0 0.8 27 5.3 0.1 3.5 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF1664 PF07889.12 EAX92666.1 - 0.033 14.2 0.1 0.033 14.2 0.1 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) DUF2383 PF09537.10 EAX92666.1 - 0.077 13.3 4.9 3.2 8.1 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF2383) DUF4611 PF15387.6 EAX92666.1 - 0.1 12.8 7.9 0.073 13.3 3.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) FlaC_arch PF05377.11 EAX92666.1 - 0.15 12.5 0.2 0.15 12.5 0.2 5.6 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EAX92666.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.6 3 1 0 3 3 3 0 Snapin/Pallidin RuvB_C PF05491.13 EAX92666.1 - 0.18 11.7 0.9 26 4.8 0.1 2.6 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain DUF4407 PF14362.6 EAX92666.1 - 0.53 9.6 10.2 0.69 9.2 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Nbl1_Borealin_N PF10444.9 EAX92666.1 - 1.2 8.8 7.6 2.4 7.9 0.0 3.7 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal DXP_synthase_N PF13292.6 EAX92666.1 - 1.6 7.8 6.3 0.21 10.8 1.6 1.9 2 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2730 PF10805.8 EAX92666.1 - 1.9 8.7 5.5 2.7 8.1 0.7 3.4 3 1 1 4 4 3 0 Protein of unknown function (DUF2730) Occludin_ELL PF07303.13 EAX92666.1 - 1.9 9.3 17.2 8.2 7.2 3.2 4.7 1 1 2 3 3 3 0 Occludin homology domain OmpH PF03938.14 EAX92666.1 - 2.2 8.6 15.5 0.59 10.5 3.0 3.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Remorin_C PF03763.13 EAX92666.1 - 2.2 8.2 7.0 6.3 6.7 3.0 2.4 2 0 0 2 2 2 0 Remorin, C-terminal region Fungal_TACC PF12709.7 EAX92666.1 - 3.9 8.0 12.3 0.23 12.0 1.3 3.5 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2203 PF09969.9 EAX92666.1 - 6.4 7.5 8.5 24 5.7 0.4 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 EAX92666.1 - 6.7 6.9 28.5 10 6.3 6.9 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EAX92666.1 - 8.2 7.0 19.3 4.5 7.8 0.8 4.2 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 EAX92666.1 - 9.4 5.8 9.1 2.8 7.4 0.2 3.3 1 1 3 4 4 4 0 fzo-like conserved region FapA PF03961.13 EAX92666.1 - 9.5 4.7 18.7 0.3 9.7 2.1 2.4 1 1 0 2 2 2 0 Flagellar Assembly Protein A SlyX PF04102.12 EAX92666.1 - 9.5 6.9 10.3 5.8 7.6 0.7 4.3 3 2 2 5 5 4 0 SlyX Ras PF00071.22 EAX92667.1 - 2.2e-49 167.1 2.3 2.7e-49 166.9 2.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92667.1 - 5e-34 117.1 0.6 7.6e-34 116.5 0.6 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92667.1 - 4e-16 59.0 0.4 4.9e-16 58.7 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX92667.1 - 6.4e-06 26.2 0.2 9.7e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX92667.1 - 7.4e-06 25.5 0.1 9.4e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX92667.1 - 0.00012 21.6 1.8 0.00036 20.1 1.8 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX92667.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX92667.1 - 0.0094 15.5 0.7 1.6 8.2 0.0 2.7 2 1 0 3 3 3 1 Ferrous iron transport protein B SCAMP PF04144.13 EAX92668.1 - 4.8e-20 72.6 20.8 5.9e-20 72.3 20.8 1.0 1 0 0 1 1 1 1 SCAMP family DUF2976 PF11190.8 EAX92668.1 - 0.057 13.2 1.7 3 7.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) 7TMR-DISM_7TM PF07695.11 EAX92668.1 - 0.2 11.5 19.1 0.3 11.0 19.1 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling FOP_dimer PF09398.10 EAX92670.1 - 3.3e-06 27.2 0.7 7.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain TFIIA PF03153.13 EAX92670.1 - 0.026 14.5 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1366 PF07104.11 EAX92670.1 - 0.029 14.1 0.3 1.2 8.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1366) RPN7 PF10602.9 EAX92672.1 - 8e-11 41.9 0.0 0.00021 21.1 0.0 3.0 2 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_1 PF00515.28 EAX92672.1 - 0.00011 21.9 2.7 0.014 15.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAX92672.1 - 0.0008 19.3 5.2 0.026 14.6 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EAX92672.1 - 0.0018 17.1 0.1 0.034 12.9 0.0 2.5 2 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 EAX92672.1 - 0.014 15.6 0.1 0.87 9.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat OSCP PF00213.18 EAX92672.1 - 0.22 11.6 4.2 0.16 12.0 0.3 2.7 4 0 0 4 4 4 0 ATP synthase delta (OSCP) subunit DUF445 PF04286.12 EAX92672.1 - 1.5 8.5 7.0 37 4.0 6.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) VirE PF05272.11 EAX92673.1 - 1.4e-05 24.9 0.1 2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAX92673.1 - 0.076 13.4 0.3 0.25 11.7 0.1 2.0 1 1 1 2 2 2 0 RNA helicase DUF4108 PF13390.6 EAX92674.1 - 2.4e-62 209.1 5.0 2.7e-62 208.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX92676.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92676.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92676.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92676.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92676.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92676.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92676.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92676.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92676.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX92676.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX92676.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX92676.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Ank_4 PF13637.6 EAX92678.1 - 7.9e-35 118.8 3.8 2.3e-14 53.6 0.1 5.2 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92678.1 - 3.3e-28 98.1 11.9 5e-12 46.2 1.6 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92678.1 - 4e-28 94.3 6.7 2.7e-06 27.3 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX92678.1 - 1.3e-24 85.5 2.2 2.5e-06 27.7 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeat DUF3447 PF11929.8 EAX92678.1 - 6.3e-24 83.7 22.1 7.4e-24 83.5 5.8 3.8 2 1 2 4 4 4 3 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX92678.1 - 4.9e-22 77.7 3.9 2.3e-12 46.9 0.2 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DrsE PF02635.15 EAX92678.1 - 0.088 13.2 0.5 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 DsrE/DsrF-like family LEM PF03020.15 EAX92678.1 - 0.15 11.7 0.0 21 4.8 0.0 3.3 3 0 0 3 3 3 0 LEM domain Ank PF00023.30 EAX92679.1 - 5.1e-10 39.4 0.1 1e-05 25.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX92679.1 - 1.1e-09 38.7 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92679.1 - 7.5e-08 32.1 0.0 6.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX92679.1 - 9.4e-07 29.3 0.2 1.7e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92679.1 - 3.3e-05 24.1 0.1 4.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92680.1 - 2.7e-22 78.9 0.1 2e-11 44.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX92680.1 - 4.6e-19 67.9 0.2 1.7e-07 31.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX92680.1 - 5.3e-17 60.2 0.1 4.7e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX92680.1 - 4.1e-16 58.8 1.7 5.8e-11 42.4 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92680.1 - 1.4e-15 57.6 2.7 2.4e-15 56.9 2.7 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Shigella_OspC PF06128.11 EAX92680.1 - 3.4e-05 23.7 1.1 0.0048 16.7 0.2 2.1 1 1 1 2 2 2 2 Shigella flexneri OspC protein PAZ_siRNAbind PF12212.8 EAX92680.1 - 0.02 14.7 0.4 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 PAZ domain Sin3_corepress PF08295.12 EAX92681.1 - 0.017 15.2 0.2 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Sin3 family co-repressor Flavodoxin_4 PF12682.7 EAX92682.1 - 0.05 13.3 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin IPPT PF01715.17 EAX92683.1 - 0.00094 19.0 0.9 0.015 15.1 0.0 3.0 3 0 0 3 3 3 1 IPP transferase DUF948 PF06103.11 EAX92683.1 - 7.5 6.9 5.5 69 3.8 0.0 4.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA_5 PF07728.14 EAX92684.1 - 5.7e-06 26.4 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FKBP_N_2 PF18023.1 EAX92684.1 - 0.017 15.2 0.7 0.028 14.5 0.7 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AAA_5 PF07728.14 EAX92685.1 - 1.1e-18 67.5 0.0 6.1e-14 52.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAX92685.1 - 0.00075 19.8 0.0 0.0063 16.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EAX92685.1 - 0.0016 18.0 2.4 0.0024 17.4 0.2 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA PF00004.29 EAX92685.1 - 0.0089 16.5 1.3 0.075 13.5 0.1 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAX92685.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_6 PF12774.7 EAX92685.1 - 0.051 12.5 2.5 1.2 8.0 0.1 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Ank_2 PF12796.7 EAX92686.1 - 1e-33 115.7 6.2 1.3e-17 64.1 0.3 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92686.1 - 6.6e-14 52.1 0.9 2.3e-06 28.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92686.1 - 1.4e-12 46.6 0.3 0.022 15.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX92686.1 - 1.5e-12 47.5 0.4 0.0022 18.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX92686.1 - 3.3e-11 43.1 0.9 0.012 16.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ras PF00071.22 EAX92687.1 - 1.8e-56 190.2 0.9 2.2e-56 190.0 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92687.1 - 6.2e-31 107.1 0.5 1e-30 106.4 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92687.1 - 4.2e-18 65.4 0.1 5.1e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX92687.1 - 2e-09 37.2 0.1 2.7e-09 36.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX92687.1 - 2.5e-06 27.5 0.1 5.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX92687.1 - 3.6e-06 26.7 0.2 0.00026 20.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX92687.1 - 0.00018 21.5 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EAX92687.1 - 0.00049 19.9 0.1 0.0038 17.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EAX92687.1 - 0.00068 19.3 0.2 0.041 13.5 0.0 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAX92687.1 - 0.0023 17.5 0.1 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region SRPRB PF09439.10 EAX92687.1 - 0.024 14.1 0.1 0.043 13.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX92687.1 - 0.066 13.6 0.0 0.088 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX92687.1 - 0.091 13.0 0.3 0.77 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAX92687.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MapZ_C2 PF18708.1 EAX92687.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 MapZ extracellular C-terminal domain 2 G-alpha PF00503.20 EAX92687.1 - 0.11 11.7 3.4 3.3 6.8 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 EAX92687.1 - 0.14 12.2 0.2 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RWD PF05773.22 EAX92689.1 - 0.00018 21.8 0.0 0.00054 20.2 0.0 1.7 1 1 0 1 1 1 1 RWD domain Imm50 PF15594.6 EAX92689.1 - 0.097 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 50 DSS1_SEM1 PF05160.13 EAX92690.1 - 3.9e-06 26.8 6.5 5.8e-06 26.3 6.5 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family Herpes_gE PF02480.16 EAX92693.1 - 0.027 13.2 0.0 0.03 13.1 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LAX PF15681.5 EAX92693.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X TRM PF02005.16 EAX92694.1 - 8.8e-108 360.8 0.0 1e-107 360.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EAX92694.1 - 1.1e-08 35.1 0.1 2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EAX92694.1 - 0.0018 17.7 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 EAX92694.1 - 0.012 14.7 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EAX92694.1 - 0.019 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF2067 PF09840.9 EAX92694.1 - 0.08 12.5 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) TPR_MLP1_2 PF07926.12 EAX92695.1 - 0.041 13.9 0.1 0.053 13.6 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX92695.1 - 2.1 8.3 10.5 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX92696.1 - 8.4e-71 236.5 11.9 9.5e-71 236.3 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TRAPP PF04051.16 EAX92697.1 - 3.3e-17 62.6 0.0 4.1e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Enolase_N PF03952.16 EAX92698.1 - 3.8e-31 108.0 0.0 2.3e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Enolase, N-terminal domain Enolase_C PF00113.22 EAX92698.1 - 1.8e-14 53.7 0.1 8.9e-14 51.4 0.0 1.9 1 1 1 2 2 2 1 Enolase, C-terminal TIM barrel domain DUF5582 PF17819.1 EAX92698.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) RIIa PF02197.17 EAX92698.1 - 0.18 11.5 0.0 0.84 9.4 0.0 2.0 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Whi5 PF08528.11 EAX92699.1 - 0.27 10.9 1.3 0.72 9.5 0.1 2.2 2 0 0 2 2 2 0 Whi5 like Arf PF00025.21 EAX92701.1 - 1.8e-74 249.0 0.0 2.1e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX92701.1 - 4.2e-13 49.6 0.0 5.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX92701.1 - 1.7e-11 43.9 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EAX92701.1 - 2.2e-11 43.6 0.0 2.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX92701.1 - 5.2e-10 39.0 0.8 1.5e-06 27.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX92701.1 - 2.9e-08 33.4 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX92701.1 - 0.00011 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAX92701.1 - 0.013 14.9 0.1 0.029 13.7 0.1 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase MeaB PF03308.16 EAX92701.1 - 0.13 11.3 0.0 0.5 9.3 0.0 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 14-3-3 PF00244.20 EAX92702.1 - 1.4e-63 214.4 3.0 1.6e-63 214.2 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4909 PF16253.5 EAX92702.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Mito_fiss_reg PF05308.11 EAX92704.1 - 0.12 12.4 0.7 0.13 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX92704.1 - 0.98 8.8 3.1 0.96 8.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMP PF05017.14 EAX92706.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat TMEM154 PF15102.6 EAX92707.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 EAX92707.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DAG1 PF05454.11 EAX92707.1 - 0.059 12.7 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) T2SSF PF00482.23 EAX92707.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DDE_1 PF03184.19 EAX92708.1 - 0.0004 20.1 0.1 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4469 PF14734.6 EAX92709.1 - 0.0031 17.6 0.2 0.011 15.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4469) with IG-like fold T6PP_N PF18572.1 EAX92709.1 - 0.0033 17.2 1.5 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF237 PF03072.14 EAX92709.1 - 0.088 12.8 1.5 1.7 8.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF237) GSH_synthase PF03199.15 EAX92709.1 - 0.75 10.3 3.5 0.54 10.7 0.1 2.4 3 0 0 3 3 3 0 Eukaryotic glutathione synthase Podoplanin PF05808.11 EAX92710.1 - 0.001 19.2 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 EAX92710.1 - 0.0079 16.1 2.1 0.018 14.9 2.1 1.5 1 0 0 1 1 1 1 Syndecan domain Otopetrin PF03189.13 EAX92710.1 - 0.019 13.8 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Otopetrin DUF5385 PF17359.2 EAX92710.1 - 0.021 14.4 0.6 0.046 13.3 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4625 PF15418.6 EAX92710.1 - 0.052 13.8 1.7 0.17 12.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4625) Trypan_PARP PF05887.11 EAX92710.1 - 0.092 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FeoB_associated PF12669.7 EAX92710.1 - 1.6 9.2 4.9 3.1 8.3 4.9 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein BTB PF00651.31 EAX92711.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain F5_F8_type_C PF00754.25 EAX92711.1 - 0.026 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Toxin_R_bind_N PF07953.12 EAX92711.1 - 0.071 12.8 0.1 0.071 12.8 0.1 2.5 3 0 0 3 3 3 0 Clostridium neurotoxin, N-terminal receptor binding DUF563 PF04577.14 EAX92712.1 - 4.4e-32 111.9 0.2 6.9e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Gly-zipper_Omp PF13488.6 EAX92714.1 - 0.15 12.1 10.7 0.23 11.5 10.7 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX92714.1 - 0.9 9.9 3.6 1.5 9.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF3839 PF12943.7 EAX92715.1 - 7.9e-132 438.1 8.7 1e-131 437.7 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ras PF00071.22 EAX92716.1 - 3e-50 170.0 0.0 3.4e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92716.1 - 7.9e-23 81.0 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92716.1 - 8.3e-07 28.6 0.0 9.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cir_N PF10197.9 EAX92716.1 - 0.3 11.3 1.9 0.57 10.4 0.5 2.1 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR RNase_PH PF01138.21 EAX92717.1 - 0.0092 16.5 0.0 0.021 15.3 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 PAP2 PF01569.21 EAX92720.1 - 1.7e-16 60.2 3.3 1.7e-16 60.2 3.3 2.2 1 1 2 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 EAX92720.1 - 0.0061 16.3 3.4 0.013 15.2 3.4 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EAX92720.1 - 0.0071 16.9 2.3 0.0071 16.9 2.3 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal FYVE_2 PF02318.16 EAX92721.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger TMP PF05017.14 EAX92723.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat AAA_7 PF12775.7 EAX92727.1 - 2.7e-06 27.0 0.5 0.00023 20.7 0.1 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_5 PF07728.14 EAX92727.1 - 0.00036 20.5 0.1 0.0083 16.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EAX92727.1 - 0.00058 19.8 0.2 0.0026 17.7 0.2 2.1 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EAX92727.1 - 0.0034 17.7 0.4 0.7 10.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EAX92727.1 - 0.029 14.7 0.1 1 9.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 EAX92727.1 - 0.036 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EAX92727.1 - 0.77 10.3 2.7 2.2 8.8 0.1 3.2 3 0 0 3 3 3 0 ABC transporter AAA PF00004.29 EAX92727.1 - 1.8 9.0 12.0 19 5.7 1.7 6.0 5 1 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAX92727.1 - 7.6 7.1 5.8 5 7.7 0.1 3.9 4 0 0 4 4 4 0 AAA domain FERM_M PF00373.18 EAX92728.1 - 6.2e-05 23.4 6.0 0.00012 22.4 0.0 4.1 4 0 0 4 4 4 1 FERM central domain Speriolin_C PF15059.6 EAX92728.1 - 0.0057 16.8 0.0 0.1 12.7 0.0 3.4 2 0 0 2 2 2 1 Speriolin C-terminus TFIID_NTD2 PF04494.15 EAX92728.1 - 1.1 9.5 7.1 32 4.8 2.1 4.6 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain UFD1 PF03152.14 EAX92732.1 - 0.043 13.3 0.6 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 PRKCSH-like PF12999.7 EAX92732.1 - 0.14 12.0 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF2682 PF10909.8 EAX92732.1 - 0.16 12.5 1.9 0.17 12.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) DDE_Tnp_4 PF13359.6 EAX92733.1 - 3.4e-18 65.8 0.0 4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX92733.1 - 1.7e-07 31.1 0.1 2.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 EAX92733.1 - 0.07 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF2486 PF10667.9 EAX92734.1 - 0.0085 16.3 6.8 0.009 16.3 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) SPATA3 PF15662.5 EAX92734.1 - 0.03 14.9 11.2 0.031 14.9 11.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pex14_N PF04695.13 EAX92734.1 - 1.3 9.7 12.5 1.5 9.5 12.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CNDH2_M PF16869.5 EAX92734.1 - 2.9 8.6 9.6 3.9 8.2 9.6 1.1 1 0 0 1 1 1 0 PF16858 TMP PF05017.14 EAX92738.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX92739.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Bromodomain PF00439.25 EAX92740.1 - 2.1e-25 88.6 0.3 4e-25 87.7 0.3 1.5 1 0 0 1 1 1 1 Bromodomain DUF1003 PF06210.11 EAX92741.1 - 0.74 9.9 3.3 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) CK_II_beta PF01214.18 EAX92742.1 - 2.7e-55 187.0 0.0 3.4e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ank_2 PF12796.7 EAX92743.1 - 3.2e-44 149.4 1.3 5.2e-19 68.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92743.1 - 4.2e-23 80.7 0.0 1.4e-05 25.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX92743.1 - 5.4e-22 75.5 0.1 8.4e-05 22.7 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX92743.1 - 3.4e-21 75.3 0.1 1.4e-09 38.3 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92743.1 - 3.4e-20 71.9 0.0 9.7e-06 25.8 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) VHS PF00790.19 EAX92743.1 - 0.27 11.1 1.6 2.1 8.2 0.1 2.8 3 0 0 3 3 3 0 VHS domain Peptidase_C98 PF15499.6 EAX92744.1 - 0.014 14.9 1.3 0.032 13.7 1.3 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TPR_2 PF07719.17 EAX92744.1 - 0.045 13.9 0.0 3.1 8.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX92744.1 - 0.084 13.2 0.0 23 5.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Voldacs PF03517.13 EAX92744.1 - 0.18 11.9 0.6 0.32 11.1 0.1 1.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF1682 PF07946.14 EAX92745.1 - 0.019 14.2 5.5 0.02 14.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CLN3 PF02487.17 EAX92745.1 - 0.074 12.1 1.2 0.11 11.5 1.2 1.2 1 0 0 1 1 1 0 CLN3 protein DUF808 PF05661.12 EAX92745.1 - 0.078 12.0 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) UPF0542 PF15086.6 EAX92745.1 - 0.19 11.6 1.0 0.37 10.7 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Presenilin PF01080.17 EAX92745.1 - 4.7 5.9 7.0 6.1 5.5 7.0 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EAX92746.1 - 9.8e-16 58.1 0.1 4e-11 43.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92746.1 - 1.3e-13 51.1 0.0 2.2e-12 47.2 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92746.1 - 1.6e-13 50.5 0.2 3.7e-07 30.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92746.1 - 7.4e-10 38.2 0.1 0.00037 20.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAX92746.1 - 1.3e-09 38.0 0.0 0.00024 21.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Sel_put PF04328.13 EAX92746.1 - 0.021 14.8 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Selenoprotein, putative Ank_2 PF12796.7 EAX92747.1 - 4e-21 75.4 0.0 4.2e-12 46.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92747.1 - 4e-17 62.1 0.0 6.4e-06 26.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92747.1 - 1.3e-16 60.7 0.0 2.8e-09 37.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX92747.1 - 1.1e-15 57.2 0.0 1.1e-06 28.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX92747.1 - 3.6e-12 45.3 0.0 0.023 15.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat DBD_Tnp_Hermes PF10683.9 EAX92747.1 - 0.11 12.1 0.0 3.8 7.3 0.0 2.8 1 1 1 3 3 3 0 Hermes transposase DNA-binding domain DUF5123 PF17161.4 EAX92748.1 - 0.011 16.8 0.2 0.013 16.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) Beta_helix PF13229.6 EAX92748.1 - 0.026 14.4 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Right handed beta helix region Rtf2 PF04641.12 EAX92749.1 - 0.001 18.5 4.7 0.001 18.5 4.7 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EAX92749.1 - 0.051 13.5 14.7 0.17 11.9 14.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Mdv1 PF11542.8 EAX92749.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial division protein 1 IFRD_C PF04836.12 EAX92749.1 - 0.13 12.8 0.3 0.32 11.6 0.3 1.7 1 0 0 1 1 1 0 Interferon-related protein conserved region Sec34 PF04136.15 EAX92749.1 - 0.28 11.0 21.1 0.49 10.3 0.1 4.4 3 1 1 4 4 4 0 Sec34-like family CdiA_C PF18451.1 EAX92749.1 - 0.34 11.2 5.8 0.18 12.0 1.2 2.6 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain zf-RING_4 PF14570.6 EAX92749.1 - 0.57 10.0 12.8 1.4 8.8 12.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1947 PF09183.10 EAX92749.1 - 0.57 10.5 4.2 0.69 10.3 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HsbA PF12296.8 EAX92749.1 - 1.3 9.4 4.8 0.43 11.0 0.4 2.3 2 1 1 3 3 2 0 Hydrophobic surface binding protein A zf-C3HC4 PF00097.25 EAX92749.1 - 3.9 7.4 14.1 18 5.3 14.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_LYR_2 PF13233.6 EAX92749.1 - 5.1 7.9 6.5 4.1 8.2 2.7 2.9 3 1 0 3 3 3 0 Complex1_LYR-like Syntaxin-6_N PF09177.11 EAX92749.1 - 5.8 7.5 18.0 0.99 10.0 3.0 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal zf-RING_2 PF13639.6 EAX92749.1 - 7.1 7.1 13.6 22 5.5 13.6 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EAX92749.1 - 7.8 6.6 12.0 48 4.1 12.1 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Enkurin PF13864.6 EAX92749.1 - 9.1 6.8 11.8 36 4.9 2.9 3.5 3 0 0 3 3 3 0 Calmodulin-binding Pox_A32 PF04665.12 EAX92752.1 - 4.9e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX92752.1 - 0.0041 17.1 0.7 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX92752.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 LRR_5 PF13306.6 EAX92754.1 - 2.3e-14 53.4 18.9 1.1e-07 31.9 8.7 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX92755.1 - 1.4e-72 241.7 75.6 3.4e-18 65.8 6.0 6.5 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92755.1 - 1.5e-09 37.5 0.0 0.45 10.3 0.0 7.8 7 2 2 9 9 9 5 Leucine rich repeat Ank PF00023.30 EAX92756.1 - 8.1e-11 41.9 0.3 1e-05 25.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX92756.1 - 1.6e-08 34.9 0.1 2.2e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92756.1 - 3.3e-08 34.0 1.3 5.9e-08 33.2 1.3 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92756.1 - 8.7e-08 31.9 0.7 0.00025 21.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX92756.1 - 0.00074 19.8 0.2 0.0015 18.8 0.1 1.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Swm2 PF17083.5 EAX92756.1 - 0.01 15.8 1.2 1.4 8.9 0.9 2.0 1 1 1 2 2 2 0 Nucleolar protein Swm2 DUF3677 PF12432.8 EAX92756.1 - 0.047 14.0 0.1 0.89 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3677) Complex1_LYR_2 PF13233.6 EAX92756.1 - 0.065 14.0 0.3 0.45 11.3 0.0 1.9 2 0 0 2 2 2 0 Complex1_LYR-like Ank_4 PF13637.6 EAX92757.1 - 3.9e-12 46.4 0.0 4.9e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92757.1 - 7.3e-10 38.2 0.1 3.6e-07 30.0 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX92757.1 - 1e-09 38.4 0.1 8.2e-07 29.2 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX92757.1 - 1.8e-09 37.6 0.1 2.3e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92757.1 - 3.6e-09 37.1 0.2 1.3e-08 35.3 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX92758.1 - 1.6e-30 105.5 5.2 6.7e-18 65.1 1.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92758.1 - 3.4e-29 100.8 0.2 1.7e-11 44.4 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX92758.1 - 8e-26 89.3 0.2 5.1e-06 26.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX92758.1 - 4.8e-24 84.1 0.4 2.8e-11 43.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92758.1 - 8.2e-23 78.0 1.0 2.2e-05 24.5 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.6 EAX92758.1 - 0.14 12.5 0.2 2.3 8.6 0.0 2.7 1 1 3 4 4 4 0 Pleckstrin homology domain Clat_adaptor_s PF01217.20 EAX92759.1 - 0.06 13.3 3.3 0.097 12.6 3.3 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain TPR_12 PF13424.6 EAX92760.1 - 1.7e-09 37.8 0.5 2.8e-07 30.7 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX92760.1 - 5.8e-05 22.8 1.3 0.021 14.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX92760.1 - 0.0016 18.1 4.8 0.0038 17.0 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX92760.1 - 0.0023 18.0 7.2 0.39 11.1 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Med8 PF10232.9 EAX92760.1 - 0.0045 16.6 5.9 0.0045 16.6 5.9 1.6 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 TPR_2 PF07719.17 EAX92760.1 - 0.0046 17.0 4.4 0.01 15.9 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAX92760.1 - 0.0051 16.6 0.6 3.4 7.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 EAX92760.1 - 0.0059 16.3 8.2 0.0066 16.2 6.8 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 EAX92760.1 - 0.056 13.1 4.9 0.86 9.3 0.6 2.5 2 0 0 2 2 2 0 TPR repeat DUF4407 PF14362.6 EAX92760.1 - 0.46 9.8 5.9 3 7.1 5.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1840 PF08895.11 EAX92760.1 - 7.4 7.0 13.8 0.61 10.4 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Hydrolase_4 PF12146.8 EAX92761.1 - 1.3e-29 103.1 0.0 1.6e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX92761.1 - 1.2e-06 29.3 0.0 1.6e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAX92761.1 - 3e-06 27.1 0.3 1.2e-05 25.1 0.2 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAX92761.1 - 0.04 13.4 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAX92761.1 - 0.048 13.5 0.0 8.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EAX92761.1 - 0.05 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EAX92761.1 - 0.053 13.2 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DUF1749 PF08538.10 EAX92761.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) IBR PF01485.21 EAX92762.1 - 8e-14 51.6 21.4 2.5e-08 34.0 8.4 4.6 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EAX92762.1 - 0.0039 17.0 4.7 0.0039 17.0 4.7 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX92762.1 - 0.0059 16.5 10.8 0.0059 16.5 10.8 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 EAX92762.1 - 0.007 16.6 3.2 0.007 16.6 3.2 3.9 3 1 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Baculo_RING PF05883.11 EAX92762.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain ESCRT-II PF05871.12 EAX92762.1 - 0.43 10.8 2.9 0.26 11.5 0.7 1.8 2 0 0 2 2 2 0 ESCRT-II complex subunit DNA_ligase_ZBD PF03119.16 EAX92762.1 - 4.4 7.4 15.4 2.1 8.4 0.2 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Guanylate_cyc PF00211.20 EAX92763.1 - 1.1e-35 122.9 0.1 1.2e-35 122.8 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Proteasome PF00227.26 EAX92763.1 - 0.099 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Proteasome subunit PAS_9 PF13426.7 EAX92764.1 - 0.00015 22.0 0.3 0.00045 20.4 0.3 1.8 1 0 0 1 1 1 1 PAS domain Spore_YpjB PF09577.10 EAX92764.1 - 0.00049 20.0 0.3 0.00087 19.2 0.3 1.4 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) CHU_C PF13585.6 EAX92764.1 - 0.043 13.9 0.5 7.4 6.7 0.5 2.7 2 0 0 2 2 2 0 C-terminal domain of CHU protein family PAS PF00989.25 EAX92764.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold DUF4728 PF15860.5 EAX92764.1 - 1.2 9.9 11.6 0.11 13.2 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) EVI2A PF05399.11 EAX92764.1 - 4.3 6.9 6.3 0.21 11.1 0.3 1.8 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Fe-S_biosyn PF01521.20 EAX92769.1 - 2.5e-08 34.1 0.0 3.2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PK PF00224.21 EAX92772.1 - 1.4e-122 408.9 6.5 2.1e-122 408.4 6.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EAX92772.1 - 7.9e-29 100.3 2.8 1.7e-28 99.2 1.2 2.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EAX92772.1 - 3.9e-05 22.9 0.9 0.00015 20.9 0.7 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EAX92772.1 - 0.0033 16.5 2.2 0.0038 16.3 0.0 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain DUF5591 PF17884.1 EAX92772.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) RRM_1 PF00076.22 EAX92773.1 - 9.2e-40 134.3 6.0 4.5e-16 58.4 0.1 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX92773.1 - 8.2e-10 38.5 0.1 0.00038 20.4 0.1 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAX92773.1 - 2.7e-05 24.2 0.1 0.00096 19.2 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EAX92773.1 - 0.0025 17.4 0.1 0.22 11.1 0.0 3.1 2 2 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAX92773.1 - 0.0066 16.5 0.0 0.23 11.6 0.0 3.0 4 0 0 4 4 4 1 Limkain b1 RL PF17797.1 EAX92773.1 - 0.033 14.1 0.1 9.4 6.3 0.0 2.9 3 0 0 3 3 3 0 RL domain RRM_3 PF08777.11 EAX92773.1 - 0.044 13.8 4.0 18 5.4 0.0 3.9 3 1 1 4 4 4 0 RNA binding motif BRAP2 PF07576.12 EAX92773.1 - 0.058 13.6 0.4 37 4.6 0.0 3.3 3 0 0 3 3 3 0 BRCA1-associated protein 2 Fe-S_biosyn PF01521.20 EAX92774.1 - 2.1e-13 50.4 0.0 2.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Rep-A_N PF04057.12 EAX92776.1 - 0.088 12.8 3.8 4 7.5 0.1 3.2 3 0 0 3 3 3 0 Replication factor-A protein 1, N-terminal domain ApoB100_C PF12491.8 EAX92776.1 - 0.73 9.8 4.0 0.28 11.2 0.4 2.4 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal E2F_TDP PF02319.20 EAX92777.1 - 1.3e-09 37.9 0.0 8.6e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Syja_N PF02383.18 EAX92778.1 - 1.7e-28 99.9 1.0 1.7e-28 99.9 1.0 2.0 2 0 0 2 2 2 1 SacI homology domain Fe_hyd_lg_C PF02906.14 EAX92779.1 - 2.5e-87 292.6 0.0 3.9e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EAX92779.1 - 8.9e-24 83.3 1.5 1.9e-23 82.3 1.5 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 EAX92779.1 - 2.2e-17 62.9 0.0 9.4e-17 60.8 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 EAX92779.1 - 3.6e-08 33.4 6.8 3.6e-08 33.4 6.8 3.0 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EAX92779.1 - 1.3e-07 31.1 11.8 1.4e-05 24.7 2.4 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 EAX92779.1 - 2.5e-06 27.5 8.2 2.5e-06 27.5 8.2 3.8 3 1 2 5 5 4 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EAX92779.1 - 9.6e-06 26.1 20.2 0.00018 22.1 11.3 3.8 2 1 2 4 4 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAX92779.1 - 2.7e-05 24.1 10.7 0.0004 20.3 1.2 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EAX92779.1 - 2.7e-05 24.5 5.9 2.7e-05 24.5 5.9 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAX92779.1 - 0.00011 23.1 0.5 0.00011 23.1 0.5 3.8 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EAX92779.1 - 0.0012 19.0 0.5 0.0012 19.0 0.5 4.1 3 1 2 5 5 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAX92779.1 - 0.0064 16.9 2.3 0.0064 16.9 2.3 4.7 6 0 0 6 6 3 2 4Fe-4S binding domain NADH-G_4Fe-4S_3 PF10588.9 EAX92779.1 - 0.011 15.2 2.4 0.011 15.2 2.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_22 PF17179.4 EAX92779.1 - 0.017 15.9 17.8 0.2 12.5 0.2 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 EAX92779.1 - 0.1 13.1 24.5 0.11 13.0 0.3 3.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EAX92779.1 - 1.4 9.7 13.7 0.7 10.7 1.2 3.6 4 0 0 4 4 3 0 4Fe-4S single cluster domain FYVE_2 PF02318.16 EAX92780.1 - 0.034 14.4 0.3 0.057 13.6 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger MFS_1 PF07690.16 EAX92781.1 - 8.8e-26 90.7 31.3 5.2e-25 88.1 11.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX92781.1 - 4.1e-14 52.0 19.6 6e-14 51.4 19.6 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF485 PF04341.12 EAX92781.1 - 0.066 13.2 0.1 0.066 13.2 0.1 4.0 4 2 0 4 4 4 0 Protein of unknown function, DUF485 SIT PF15330.6 EAX92782.1 - 0.027 14.9 0.2 0.047 14.1 0.0 1.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT WBP-1 PF11669.8 EAX92782.1 - 0.071 13.8 0.2 0.094 13.4 0.2 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 LapA_dom PF06305.11 EAX92782.1 - 0.084 12.7 0.5 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 EAX92783.1 - 3.9e-67 226.4 0.0 5.4e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92783.1 - 1.7e-35 122.6 0.0 2.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX92783.1 - 3.5e-05 22.9 0.1 7.8e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX92783.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX92783.1 - 0.00074 19.2 0.0 1.4 8.5 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Neuro_bHLH PF12533.8 EAX92783.1 - 0.0017 19.6 0.0 0.0064 17.7 0.0 1.9 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor Kinase-like PF14531.6 EAX92783.1 - 0.0036 16.7 0.0 0.0099 15.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAX92783.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PSP PF04046.16 EAX92784.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92785.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4116 PF13475.6 EAX92787.1 - 0.026 14.3 2.0 0.05 13.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX92789.1 - 2.2e-72 242.5 3.1 3.1e-72 242.0 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) HTH_23 PF13384.6 EAX92790.1 - 5.6e-11 41.9 0.0 1.6e-06 27.8 0.1 2.1 2 0 0 2 2 2 2 Homeodomain-like domain Myb_DNA-binding PF00249.31 EAX92790.1 - 4.7e-07 29.9 1.9 8.6e-07 29.1 0.8 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_38 PF13936.6 EAX92790.1 - 1.6e-06 27.8 0.1 0.0075 16.0 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Sigma70_r4 PF04545.16 EAX92790.1 - 4.1e-06 26.2 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_IclR PF09339.10 EAX92790.1 - 4.5e-05 23.2 0.0 0.00072 19.3 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_29 PF13551.6 EAX92790.1 - 5e-05 23.2 0.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EAX92790.1 - 7.4e-05 23.3 0.1 0.0016 19.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Myb_DNA-bind_6 PF13921.6 EAX92790.1 - 0.00015 21.9 0.4 0.00024 21.3 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_28 PF13518.6 EAX92790.1 - 0.00048 20.2 0.1 0.026 14.7 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EAX92790.1 - 0.0012 18.4 0.1 0.73 9.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 DUF722 PF05263.11 EAX92790.1 - 0.002 18.4 0.1 0.0026 18.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF722) PCI PF01399.27 EAX92790.1 - 0.0065 17.0 0.0 0.0094 16.4 0.0 1.2 1 0 0 1 1 1 1 PCI domain HTH_24 PF13412.6 EAX92790.1 - 0.0071 15.9 0.1 0.038 13.5 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding SpoIIID PF12116.8 EAX92790.1 - 0.0081 16.2 0.0 0.61 10.2 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_10 PF04967.12 EAX92790.1 - 0.0082 15.9 0.0 0.025 14.4 0.0 1.7 2 0 0 2 2 2 1 HTH DNA binding domain HTH_11 PF08279.12 EAX92790.1 - 0.009 15.9 0.4 0.11 12.4 0.1 2.1 2 0 0 2 2 2 1 HTH domain DUF746 PF05344.11 EAX92790.1 - 0.0093 15.8 0.0 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) HTH_35 PF13693.6 EAX92790.1 - 0.013 15.5 0.0 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EAX92790.1 - 0.013 15.3 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 EAX92790.1 - 0.014 15.3 0.2 0.69 9.9 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 EAX92790.1 - 0.022 14.4 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MarR PF01047.22 EAX92790.1 - 0.022 14.7 0.0 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_AsnC-type PF13404.6 EAX92790.1 - 0.023 14.5 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Terminase_5 PF06056.12 EAX92790.1 - 0.025 14.5 1.8 0.066 13.1 0.6 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) YdaS_antitoxin PF15943.5 EAX92790.1 - 0.049 13.5 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_ISL3 PF13542.6 EAX92790.1 - 0.053 12.9 0.0 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Phage_terminase PF10668.9 EAX92790.1 - 0.083 12.9 0.8 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Phage terminase small subunit HTH_3 PF01381.22 EAX92790.1 - 0.093 12.8 0.0 0.76 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix DUF4817 PF16087.5 EAX92790.1 - 0.11 12.3 0.7 0.5 10.2 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) MarR_2 PF12802.7 EAX92790.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Ank PF00023.30 EAX92791.1 - 5.9e-75 244.7 13.8 3.3e-09 36.8 0.0 12.3 12 0 0 12 12 12 11 Ankyrin repeat Ank_2 PF12796.7 EAX92791.1 - 1.6e-73 243.3 44.2 3e-18 66.2 3.6 7.3 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92791.1 - 1.6e-72 239.0 22.6 2.4e-13 50.3 0.2 11.9 5 1 7 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92791.1 - 9.8e-67 213.0 23.6 3.9e-06 26.8 0.0 13.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 EAX92791.1 - 1.6e-44 149.4 16.0 3.6e-11 43.1 0.1 8.1 4 2 2 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92791.1 - 7e-34 115.6 8.8 7e-34 115.6 8.8 5.8 4 2 1 5 5 5 2 Domain of unknown function (DUF3447) ATPase PF06745.13 EAX92791.1 - 0.065 12.6 0.1 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 KaiC DHBP_synthase PF00926.19 EAX92791.1 - 0.089 12.3 0.3 39 3.7 0.0 3.6 3 1 1 4 4 4 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Ad_Cy_reg PF16701.5 EAX92791.1 - 0.22 11.3 0.0 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Adenylate cyclase regulatory domain Ank_4 PF13637.6 EAX92792.1 - 8.1e-53 176.2 19.1 3.2e-14 53.1 0.7 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX92792.1 - 3e-41 138.1 19.4 4.1e-07 30.2 0.1 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.7 EAX92792.1 - 2.7e-38 130.4 27.5 3.1e-18 66.1 4.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92792.1 - 1.9e-33 110.7 19.1 9.7e-06 25.6 0.3 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX92792.1 - 8.4e-30 102.5 10.6 3.5e-11 43.1 1.0 4.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX92792.1 - 7.1e-06 26.0 11.2 0.0037 17.0 1.0 4.1 2 1 2 4 4 4 2 Shigella flexneri OspC protein RNase_PH_C PF03725.15 EAX92792.1 - 0.0044 17.0 3.0 10 6.3 0.0 4.3 1 1 4 5 5 5 1 3' exoribonuclease family, domain 2 DUF3677 PF12432.8 EAX92792.1 - 0.0069 16.7 3.5 4.9 7.5 0.3 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF3677) Arg_repressor PF01316.21 EAX92792.1 - 0.0098 15.6 2.2 42 4.0 0.0 4.6 4 1 1 5 5 5 0 Arginine repressor, DNA binding domain MetallophosN PF16371.5 EAX92792.1 - 0.082 13.2 0.0 2.7 8.3 0.0 2.8 2 1 1 3 3 3 0 N terminal of Calcineurin-like phosphoesterase S10_plectin PF03501.15 EAX92792.1 - 0.26 11.4 4.3 18 5.5 0.1 3.9 1 1 4 5 5 5 0 Plectin/S10 domain BRCT_2 PF16589.5 EAX92792.1 - 0.34 11.4 10.4 3e+03 -1.3 10.4 4.3 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain TubC_N PF18563.1 EAX92792.1 - 0.61 10.1 9.2 5 7.2 0.3 3.3 3 0 0 3 3 3 0 TubC N-terminal docking domain Corazonin PF17308.2 EAX92792.1 - 1.3 9.4 9.7 2.7 8.4 2.6 3.3 2 1 1 3 3 3 0 Pro-corazonin NPL PF17800.1 EAX92793.1 - 7.9e-11 42.5 0.0 1.6e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin-like domain Peptidase_C48 PF02902.19 EAX92794.1 - 1.9e-15 57.3 0.3 8.8e-15 55.1 0.3 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S28 PF05577.12 EAX92795.1 - 5.1e-34 117.8 0.9 5.1e-29 101.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EAX92795.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4832 PF16116.5 EAX92796.1 - 1.4e-06 28.4 0.1 2.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) Y_Y_Y PF07495.13 EAX92796.1 - 0.16 11.9 3.1 0.22 11.5 1.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain EF-hand_6 PF13405.6 EAX92797.1 - 2.3e-09 36.4 0.4 0.002 17.9 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EAX92797.1 - 7.8e-09 35.9 0.2 0.0016 18.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX92797.1 - 1.3e-08 33.8 0.6 0.002 17.5 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EAX92797.1 - 0.0014 18.9 0.1 0.39 11.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EAX92797.1 - 0.056 13.3 1.5 29 4.6 0.1 3.4 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 EAX92797.1 - 0.11 12.0 3.8 0.23 11.0 0.6 2.4 2 0 0 2 2 2 0 EF hand Gly_radical PF01228.21 EAX92798.1 - 0.067 13.7 0.5 0.49 11.0 0.0 2.4 2 1 0 2 2 2 0 Glycine radical DUF1140 PF06600.11 EAX92798.1 - 0.81 10.2 4.4 15 6.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1140) DUF3908 PF13048.6 EAX92798.1 - 1.4 9.2 10.5 9.7 6.5 4.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3908) LRR_5 PF13306.6 EAX92799.1 - 1.7e-124 409.5 78.5 7.3e-28 97.1 1.3 8.1 2 2 4 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX92799.1 - 2.1e-24 85.0 19.0 0.00063 19.4 0.0 11.4 7 3 6 13 13 13 9 Leucine rich repeat DUF1351 PF07083.11 EAX92800.1 - 0.0081 16.0 0.4 0.0081 16.0 0.4 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF1351) SF-assemblin PF06705.11 EAX92800.1 - 0.028 13.7 3.0 0.037 13.4 3.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Sec8_exocyst PF04048.14 EAX92800.1 - 0.045 13.6 5.0 0.11 12.4 4.2 1.8 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain ParB PF08775.10 EAX92800.1 - 0.061 13.8 3.8 0.075 13.5 1.3 2.0 2 0 0 2 2 2 0 ParB family DUF4407 PF14362.6 EAX92800.1 - 0.089 12.1 0.9 0.1 12.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 EAX92800.1 - 0.094 12.3 5.0 0.15 11.6 4.8 1.4 1 1 0 1 1 1 0 fzo-like conserved region Jnk-SapK_ap_N PF09744.9 EAX92800.1 - 0.13 12.5 4.6 0.24 11.6 4.6 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1043 PF06295.12 EAX92800.1 - 0.85 9.6 10.0 0.1 12.6 5.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Com_YlbF PF06133.11 EAX92800.1 - 1.1 10.0 13.8 0.29 11.7 3.3 2.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Occludin_ELL PF07303.13 EAX92800.1 - 1.8 9.3 11.6 0.16 12.7 2.5 2.4 1 1 1 2 2 2 0 Occludin homology domain OmpH PF03938.14 EAX92800.1 - 4.9 7.5 13.9 4.1 7.7 6.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Yip1 PF04893.17 EAX92801.1 - 9.7e-06 25.4 13.3 2e-05 24.4 12.9 1.7 1 1 0 1 1 1 1 Yip1 domain GWT1 PF06423.12 EAX92801.1 - 0.077 13.1 6.8 0.064 13.4 1.5 2.2 2 0 0 2 2 2 0 GWT1 Cullin PF00888.22 EAX92802.1 - 3.5e-24 85.4 8.1 4.6e-24 85.0 8.1 1.1 1 0 0 1 1 1 1 Cullin family GtrA PF04138.14 EAX92803.1 - 0.078 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 GtrA-like protein WD40 PF00400.32 EAX92804.1 - 1.1e-10 41.9 11.8 0.0034 18.2 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX92804.1 - 5.4e-10 39.4 0.0 0.00024 21.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX92804.1 - 4.7e-07 29.4 0.5 9.5e-05 21.9 0.1 2.5 2 1 0 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 EAX92804.1 - 0.016 14.0 0.8 0.77 8.4 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like SUKH_6 PF14568.6 EAX92804.1 - 0.048 14.1 0.3 0.91 10.0 0.0 2.5 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Hira PF07569.11 EAX92804.1 - 0.059 13.1 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split Peptidase_S31 PF05578.12 EAX92804.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 GPS2_interact PF15784.5 EAX92805.1 - 0.099 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain AAA_13 PF13166.6 EAX92806.1 - 0.00097 17.9 6.0 0.001 17.8 6.0 1.0 1 0 0 1 1 1 1 AAA domain ApoO PF09769.9 EAX92806.1 - 0.25 11.3 1.0 1.1 9.3 1.1 1.8 1 1 0 1 1 1 0 Apolipoprotein O DUF1640 PF07798.11 EAX92806.1 - 0.56 10.2 5.7 1.5 8.8 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) WW_like PF17890.1 EAX92807.1 - 0.38 10.8 4.0 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain Pox_A32 PF04665.12 EAX92808.1 - 3.9e-07 29.8 2.8 3.9e-07 29.8 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX92808.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX92808.1 - 6.3e-05 22.8 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX92808.1 - 0.00016 21.7 3.4 0.00036 20.6 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92808.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX92808.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX92808.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX92808.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX92808.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX92808.1 - 0.087 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX92808.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX92808.1 - 0.39 11.0 4.3 7.8 6.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) T5orf172 PF10544.9 EAX92809.1 - 3.8e-07 30.6 0.1 8.7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX92809.1 - 0.017 15.0 0.3 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain RNA_bind PF08675.11 EAX92809.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain DUF3839 PF12943.7 EAX92810.1 - 1.3e-157 522.5 13.5 1.5e-157 522.2 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX92810.1 - 0.13 12.7 0.3 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX92810.1 - 0.92 10.0 6.8 2.1 8.8 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_D5 PF03288.16 EAX92811.1 - 3.1e-05 24.4 2.6 0.00018 21.9 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX92812.1 - 5.7e-61 204.6 6.9 6.3e-61 204.5 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX92813.1 - 1.4 8.8 4.2 2.9 7.8 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_11 PF13086.6 EAX92814.1 - 0.003 17.4 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX92814.1 - 0.0075 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX92814.1 - 0.0082 16.5 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX92814.1 - 0.026 14.5 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX92814.1 - 0.043 13.3 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX92814.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NAD_binding_8 PF13450.6 EAX92815.1 - 0.21 11.9 0.0 0.57 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3199 PF11436.8 EAX92816.1 - 0.074 13.1 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) ANAPC4_WD40 PF12894.7 EAX92818.1 - 7.6e-13 48.6 0.0 0.00035 20.8 0.0 6.0 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX92818.1 - 1.1e-12 48.3 14.5 0.00045 21.0 1.3 7.5 7 1 1 8 8 8 3 WD domain, G-beta repeat WD40_like PF17005.5 EAX92818.1 - 2.8e-06 26.9 0.5 0.39 10.0 0.2 3.5 1 1 2 3 3 3 3 WD40-like domain LisH PF08513.11 EAX92818.1 - 7.9e-06 25.6 0.1 1.9e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 LisH MMS1_N PF10433.9 EAX92818.1 - 0.00016 20.4 0.1 0.0034 16.1 0.0 2.6 1 1 2 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RAB3GAP2_N PF14655.6 EAX92818.1 - 0.00038 19.8 0.1 0.34 10.1 0.0 3.6 2 2 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Mcl1_mid PF12341.8 EAX92818.1 - 0.0023 17.3 0.0 0.88 8.9 0.0 2.7 1 1 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region BBS2_Mid PF14783.6 EAX92818.1 - 0.0029 17.6 0.0 5.6 7.1 0.0 3.6 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EAX92818.1 - 0.0038 17.1 0.0 4.2 7.2 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EAX92818.1 - 0.0098 14.3 0.0 0.038 12.3 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EAX92818.1 - 0.01 14.8 0.1 0.31 10.0 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fascin PF06268.13 EAX92818.1 - 0.15 12.3 0.0 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 Fascin domain DUF3447 PF11929.8 EAX92820.1 - 8.9e-13 48.0 2.9 8.9e-13 48.0 2.9 3.2 2 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX92820.1 - 8.4e-06 26.3 1.3 0.00021 21.8 0.3 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92820.1 - 0.0027 18.1 2.7 51 4.9 0.2 5.1 5 1 1 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 EAX92820.1 - 0.0042 17.6 2.1 18 6.1 0.4 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92820.1 - 0.051 13.9 0.4 1 9.8 0.0 3.1 3 1 0 4 4 4 0 Ankyrin repeats (many copies) Zincin_2 PF10103.9 EAX92821.1 - 0.21 10.8 0.0 0.24 10.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase Gly-zipper_YMGG PF13441.6 EAX92821.1 - 3.6 7.4 17.4 2.4 8.0 15.8 1.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper EAP30 PF04157.16 EAX92822.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 EAP30/Vps36 family Hemocyanin_N PF03722.14 EAX92822.1 - 0.17 12.4 1.6 0.17 12.4 0.8 1.4 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain NAF PF03822.14 EAX92822.1 - 0.17 12.1 1.9 0.56 10.4 0.3 2.3 2 1 0 2 2 2 0 NAF domain IFT20 PF14931.6 EAX92822.1 - 0.17 12.0 7.3 0.25 11.5 7.3 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF3659 PF12396.8 EAX92823.1 - 0.011 15.6 7.0 4.8 7.2 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3659) HIP1_clath_bdg PF16515.5 EAX92823.1 - 0.012 16.2 9.0 0.012 16.2 9.0 5.2 3 1 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Snapin_Pallidin PF14712.6 EAX92823.1 - 0.019 15.4 1.2 0.019 15.4 1.2 4.5 4 0 0 4 4 4 0 Snapin/Pallidin HTH_6 PF01418.17 EAX92823.1 - 0.07 13.1 1.0 2.8 8.0 0.5 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family GAS PF13851.6 EAX92823.1 - 0.082 12.3 41.7 0.066 12.6 0.4 4.4 3 2 0 4 4 4 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EAX92823.1 - 0.14 12.6 29.7 0.94 9.9 2.0 3.5 2 1 0 2 2 2 0 Fez1 MCC-bdg_PDZ PF10506.9 EAX92823.1 - 0.19 11.8 16.2 0.65 10.1 3.4 4.5 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SOGA PF11365.8 EAX92823.1 - 0.21 12.7 18.6 0.36 12.0 3.5 3.3 3 0 0 3 3 3 0 Protein SOGA Exonuc_VII_L PF02601.15 EAX92823.1 - 0.37 10.3 22.6 0.012 15.2 2.6 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit CALCOCO1 PF07888.11 EAX92823.1 - 0.5 9.2 18.5 0.35 9.7 10.7 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like GCN5L1 PF06320.13 EAX92823.1 - 0.66 10.1 17.6 0.58 10.3 9.9 3.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Nsp1_C PF05064.13 EAX92823.1 - 0.83 9.5 22.5 0.081 12.7 8.4 4.3 3 1 1 4 4 4 0 Nsp1-like C-terminal region Suppressor_APC PF11414.8 EAX92823.1 - 0.89 9.7 6.9 1.4 9.0 0.4 2.9 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Jnk-SapK_ap_N PF09744.9 EAX92823.1 - 1.8 8.7 23.7 0.24 11.6 10.7 3.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 EAX92823.1 - 2 8.3 27.5 0.081 12.7 2.9 5.6 5 1 0 5 5 5 0 Septum formation initiator TMF_TATA_bd PF12325.8 EAX92823.1 - 2.2 8.6 37.2 0.9 9.8 8.5 5.4 2 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EAX92823.1 - 2.2 9.2 26.3 0.45 11.4 2.5 4.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 EAX92823.1 - 2.9 7.7 32.0 0.066 13.0 13.9 3.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4164 PF13747.6 EAX92823.1 - 4.6 7.6 11.0 0.99 9.7 4.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) MscS_porin PF12795.7 EAX92823.1 - 5.7 6.4 28.9 0.78 9.2 6.1 3.2 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain MIS13 PF08202.11 EAX92823.1 - 9.3 5.4 22.5 0.032 13.5 8.2 2.6 2 1 0 2 2 2 0 Mis12-Mtw1 protein family UPF0223 PF05256.12 EAX92824.1 - 9.3e-05 22.7 12.2 0.38 11.1 1.3 3.1 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0223) KRAB PF01352.27 EAX92824.1 - 0.00026 20.6 0.5 6.1 6.6 0.0 3.7 3 0 0 3 3 3 1 KRAB box SAM_Exu PF18609.1 EAX92824.1 - 0.0045 17.1 5.6 0.52 10.4 0.6 3.1 1 1 2 3 3 3 1 Exuperantia SAM-like domain DUF3644 PF12358.8 EAX92824.1 - 0.0052 17.2 1.3 18 5.9 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3644) SpecificRecomb PF10136.9 EAX92824.1 - 0.0073 14.7 0.9 0.0085 14.5 0.9 1.0 1 0 0 1 1 1 1 Site-specific recombinase PAS_2 PF08446.11 EAX92824.1 - 0.0086 16.7 3.2 1.3 9.7 0.4 2.3 1 1 1 2 2 2 2 PAS fold DUF2358 PF10184.9 EAX92824.1 - 0.01 16.1 2.3 23 5.3 0.1 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2358) Endopep_inhib PF16800.5 EAX92824.1 - 0.039 13.9 8.2 3.8 7.4 0.8 3.0 1 1 2 3 3 3 0 IseA DL-endopeptidase inhibitor CCDC117 PF15810.5 EAX92824.1 - 0.039 14.3 3.6 0.47 10.7 1.3 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 117 FtsK_gamma PF09397.10 EAX92824.1 - 0.061 13.1 3.0 15 5.5 0.1 3.4 3 0 0 3 3 3 0 Ftsk gamma domain L_biotic_typeA PF04604.13 EAX92824.1 - 0.063 13.1 2.3 2.2 8.2 0.1 3.1 4 0 0 4 4 4 0 Type-A lantibiotic DUF445 PF04286.12 EAX92824.1 - 0.071 12.9 5.7 0.086 12.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ParD PF09386.10 EAX92824.1 - 0.073 13.5 4.8 0.7 10.3 0.8 2.3 1 1 1 2 2 2 0 Antitoxin ParD L27 PF02828.16 EAX92824.1 - 0.08 12.7 2.5 16 5.3 0.1 3.6 4 0 0 4 4 4 0 L27 domain P5-ATPase PF12409.8 EAX92824.1 - 0.62 10.2 8.7 6 7.0 2.3 2.4 1 1 1 2 2 2 0 P5-type ATPase cation transporter DnaI_N PF07319.11 EAX92824.1 - 0.74 10.5 8.1 1.7 9.4 3.2 2.0 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus TMIE PF16038.5 EAX92824.1 - 5.4 6.9 5.9 7.6 6.4 0.5 2.4 1 1 1 2 2 2 0 TMIE protein ArsC PF03960.15 EAX92825.1 - 0.7 9.9 4.2 0.43 10.6 0.2 2.7 2 1 0 2 2 2 0 ArsC family LMBR1 PF04791.16 EAX92825.1 - 2.7 6.8 11.5 3.8 6.3 11.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3839 PF12943.7 EAX92826.1 - 6.9e-156 516.8 13.8 8.5e-156 516.5 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX92826.1 - 0.14 12.0 0.9 0.58 10.0 0.9 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX92826.1 - 0.43 11.1 6.2 0.94 10.0 1.1 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX92826.1 - 1.1 9.8 4.8 1.7 9.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX92827.1 - 3.2e-42 142.9 0.9 6.2e-42 142.0 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX92828.1 - 9.4e-09 34.6 1.3 1.7e-08 33.8 1.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX92828.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX92828.1 - 0.16 11.9 0.1 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX92829.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX92829.1 - 0.065 13.2 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX92830.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX92830.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX92831.1 - 0.012 15.6 0.2 0.017 15.1 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX92832.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX92832.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SPG48 PF14764.6 EAX92836.1 - 0.021 15.3 0.1 0.7 10.4 0.0 3.2 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Vac14_Fab1_bd PF12755.7 EAX92836.1 - 1.1 9.9 5.5 2.1 9.0 0.2 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DnaJ_C PF01556.18 EAX92839.1 - 4.8e-16 59.2 0.0 6.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX92839.1 - 3.2e-11 43.2 1.8 1.2e-10 41.4 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EAX92840.1 - 0.0017 18.3 0.0 0.011 15.8 0.0 2.3 2 1 1 3 3 3 1 Thioredoxin DUF3271 PF11675.8 EAX92840.1 - 0.0067 15.7 0.5 0.091 12.0 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3271) Thioredoxin_6 PF13848.6 EAX92840.1 - 0.12 12.3 5.3 0.5 10.2 1.1 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain EMP70 PF02990.16 EAX92842.1 - 1.4e-26 93.3 32.6 8.4e-26 90.7 32.6 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Bromodomain PF00439.25 EAX92843.1 - 1.1e-18 67.1 0.5 8.1e-18 64.3 0.1 2.3 2 0 0 2 2 2 1 Bromodomain Fur_reg_FbpB PF13040.6 EAX92843.1 - 0.022 14.3 1.5 0.035 13.6 0.2 2.1 2 0 0 2 2 2 0 Fur-regulated basic protein B His_Phos_2 PF00328.22 EAX92844.1 - 2.2e-20 73.4 0.0 3.4e-11 43.1 0.0 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3269 PF11673.8 EAX92844.1 - 0.077 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Abhydrolase_1 PF00561.20 EAX92845.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold IFT81_CH PF18383.1 EAX92846.1 - 2.8 8.2 8.1 10 6.4 0.1 4.1 4 1 0 5 5 5 0 Intraflagellar transport 81 calponin homology domain BH3 PF15285.6 EAX92847.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Ank_2 PF12796.7 EAX92848.1 - 0.0001 22.8 0.0 0.00014 22.3 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92848.1 - 0.0003 21.0 0.1 0.0012 19.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAX92848.1 - 0.0074 16.7 0.2 0.017 15.6 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EAX92848.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92848.1 - 0.024 15.2 0.1 0.063 13.9 0.1 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Pox_A32 PF04665.12 EAX92849.1 - 3.8e-08 33.1 1.2 1.5e-07 31.2 0.1 2.2 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX92849.1 - 0.042 14.0 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX92849.1 - 0.12 12.0 0.2 3.7 7.1 0.2 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) YmgB PF10798.8 EAX92851.1 - 0.035 13.9 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Phi-29_GP4 PF05464.11 EAX92851.1 - 0.093 13.0 0.4 0.28 11.5 0.1 1.8 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) EF-hand_10 PF14788.6 EAX92852.1 - 0.0017 18.1 0.3 0.032 14.1 0.1 2.7 2 0 0 2 2 2 1 EF hand Zn_ribbon_2 PF12674.7 EAX92852.1 - 0.023 15.3 2.4 2 9.1 0.0 3.4 2 1 1 3 3 3 0 Putative zinc ribbon domain DUF4106 PF13388.6 EAX92853.1 - 1.6e-176 587.6 21.0 1.6e-176 587.6 21.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX92853.1 - 0.07 13.4 3.1 0.95 9.8 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated Pkinase PF00069.25 EAX92854.1 - 5.5e-25 88.2 0.1 9.9e-25 87.4 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92854.1 - 1.8e-13 50.4 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX92854.1 - 8.6e-05 21.5 0.1 0.00013 20.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX92854.1 - 0.0017 18.3 0.0 0.2 11.5 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX92854.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX92854.1 - 0.025 13.9 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like UN_NPL4 PF11543.8 EAX92855.1 - 0.036 14.6 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 KIAA1430 PF13879.6 EAX92856.1 - 0.0029 18.4 5.6 0.0029 18.4 5.6 2.9 2 1 0 2 2 2 1 KIAA1430 homologue RapH_N PF18801.1 EAX92856.1 - 0.82 9.8 5.6 6.9 6.8 1.2 2.5 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF5301 PF17225.3 EAX92857.1 - 0.4 11.1 4.3 0.95 9.9 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) PHD PF00628.29 EAX92858.1 - 7.7e-18 64.1 21.1 3.7e-11 42.7 6.5 2.3 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EAX92858.1 - 1.9e-08 33.7 11.3 8.5e-06 25.2 3.2 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EAX92858.1 - 0.27 11.2 22.4 0.25 11.3 2.2 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 EAX92858.1 - 0.3 11.5 18.4 0.36 11.3 6.9 3.1 2 1 0 3 3 3 0 Restriction alleviation protein Lar C1_2 PF03107.16 EAX92858.1 - 1.1 9.7 22.9 0.58 10.5 2.7 3.5 3 1 0 3 3 3 0 C1 domain FYVE_2 PF02318.16 EAX92858.1 - 1.4 9.2 14.9 0.85 9.8 3.4 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.6 EAX92858.1 - 1.7 9.0 21.6 0.36 11.2 6.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_9 PF13901.6 EAX92858.1 - 2.7 7.9 16.4 14 5.6 10.6 2.5 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon ETRAMP PF09716.10 EAX92860.1 - 0.00022 21.2 0.6 0.00053 20.0 0.6 1.8 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) CEND1 PF15677.5 EAX92860.1 - 0.049 14.2 1.1 0.11 13.0 1.1 1.6 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 DUF1439 PF07273.12 EAX92860.1 - 0.12 12.2 0.6 1.1 9.1 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1439) TetR_C_22 PF17928.1 EAX92861.1 - 0.052 13.9 2.5 0.23 11.8 0.1 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 EAX92861.1 - 0.34 11.2 4.3 4.9 7.5 0.5 2.7 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF99 PF01949.16 EAX92861.1 - 0.49 9.8 4.4 0.27 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF99 SpoIISA_toxin PF14171.6 EAX92861.1 - 0.56 9.9 6.6 0.16 11.6 0.9 2.1 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Sec8_exocyst PF04048.14 EAX92861.1 - 3.2 7.6 12.5 0.38 10.6 3.1 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain YpjP PF14005.6 EAX92861.1 - 4.4 7.4 12.2 6.3 6.8 4.2 2.7 1 1 1 2 2 2 0 YpjP-like protein Med9 PF07544.13 EAX92861.1 - 9.4 6.4 19.8 1.2 9.3 9.6 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ank_2 PF12796.7 EAX92863.1 - 3.7e-15 56.3 3.2 1.2e-05 25.8 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92863.1 - 4.3e-13 49.5 2.3 7.8e-07 29.5 0.0 5.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92863.1 - 3.4e-12 45.4 4.6 0.0025 18.2 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 EAX92863.1 - 3.5e-08 33.6 4.1 8.2e-06 26.0 0.0 4.3 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX92863.1 - 0.0023 18.3 4.3 0.28 11.7 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat Tax PF02959.16 EAX92864.1 - 0.086 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax SNAP PF14938.6 EAX92865.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF5421 PF17458.2 EAX92866.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) LRR_4 PF12799.7 EAX92867.1 - 3.1e-34 116.4 53.6 1e-06 28.9 1.0 12.4 7 4 4 13 13 13 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 EAX92867.1 - 1.9e-30 106.4 0.0 2.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAX92867.1 - 4.1e-30 103.3 36.8 1.5e-05 24.6 0.5 10.8 9 3 2 11 11 11 7 Leucine rich repeat LRR_6 PF13516.6 EAX92867.1 - 7.5e-10 38.1 33.9 0.62 10.3 0.0 13.5 14 1 1 15 15 15 3 Leucine Rich repeat LRR_1 PF00560.33 EAX92867.1 - 1.6e-05 24.8 45.3 1.4 9.8 0.3 13.6 15 3 0 15 15 15 3 Leucine Rich Repeat LRR_9 PF14580.6 EAX92867.1 - 0.0041 16.6 23.2 0.16 11.4 2.7 5.3 3 2 2 5 5 5 2 Leucine-rich repeat LRR_5 PF13306.6 EAX92867.1 - 0.075 13.0 16.0 0.18 11.8 5.5 3.9 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PP2C_2 PF13672.6 EAX92867.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CREPT PF16566.5 EAX92867.1 - 1.7 8.8 9.4 1.5 9.0 0.1 4.1 5 0 0 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour Seadorna_VP6 PF07407.11 EAX92868.1 - 0.29 10.0 4.7 0.16 10.9 3.1 1.4 1 1 1 2 2 2 0 Seadornavirus VP6 protein YjbH PF06082.11 EAX92868.1 - 3.9 6.2 6.1 4.4 6.0 6.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH PSP PF04046.16 EAX92869.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92870.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX92871.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.4 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX92871.1 - 0.059 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) MeaB PF03308.16 EAX92871.1 - 0.067 12.2 0.5 0.12 11.3 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAX92871.1 - 0.091 13.2 3.9 0.19 12.2 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX92871.1 - 0.27 11.0 9.0 0.42 10.4 9.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ComA PF02679.15 EAX92873.1 - 0.095 12.1 0.8 0.12 11.9 0.8 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chal_sti_synt_N PF00195.19 EAX92873.1 - 0.15 11.5 0.4 0.27 10.6 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Bromodomain PF00439.25 EAX92874.1 - 1.5e-20 73.1 0.3 3.3e-20 71.9 0.2 1.6 1 1 0 1 1 1 1 Bromodomain BET PF17035.5 EAX92874.1 - 0.017 15.3 0.8 0.048 13.8 0.8 1.9 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Ank_4 PF13637.6 EAX92875.1 - 1.1e-40 137.5 16.1 7.1e-10 39.2 0.1 9.0 4 1 5 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX92875.1 - 4.3e-34 117.0 16.5 4.1e-14 52.9 0.7 5.5 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92875.1 - 9.5e-32 108.1 7.5 8.9e-06 25.9 0.0 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX92875.1 - 7.2e-29 99.5 5.4 1.7e-07 31.3 0.1 6.7 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92875.1 - 2.6e-26 88.8 16.0 5.1e-05 23.4 0.0 10.2 10 2 1 11 11 11 6 Ankyrin repeat DUF3447 PF11929.8 EAX92875.1 - 6.4e-25 86.9 4.8 6.4e-25 86.9 4.8 4.9 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) HERV-K_env_2 PF13804.6 EAX92875.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein RL PF17797.1 EAX92875.1 - 0.014 15.3 0.4 0.1 12.5 0.1 2.6 3 0 0 3 3 3 0 RL domain MetallophosN PF16371.5 EAX92875.1 - 0.015 15.5 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase ubiquitin PF00240.23 EAX92877.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Beach PF02138.18 EAX92878.1 - 9.7e-105 349.9 0.0 9.7e-105 349.9 0.0 2.8 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 EAX92878.1 - 1.2e-27 96.8 2.3 1.2e-27 96.8 2.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAX92878.1 - 4e-08 33.3 0.9 1.2e-06 28.6 0.1 3.2 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 EAX92878.1 - 4e-06 26.3 2.0 1.3e-05 24.6 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF1088 PF06469.11 EAX92878.1 - 0.01 15.5 0.2 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) ANAPC4_WD40 PF12894.7 EAX92878.1 - 0.011 16.0 0.0 5.2 7.4 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 EAX92878.1 - 0.13 12.2 2.4 1.1 9.2 0.0 3.5 3 0 0 3 3 3 0 GRAM domain SopA PF13981.6 EAX92878.1 - 0.23 11.9 2.9 0.64 10.5 0.3 3.2 3 0 0 3 3 3 0 SopA-like central domain PIN_8 PF18476.1 EAX92878.1 - 5 6.9 7.3 9.2 6.0 2.3 2.4 2 0 0 2 2 2 0 PIN like domain Peptidase_M18 PF02127.15 EAX92879.1 - 2.4e-66 224.3 2.9 2.8e-39 135.1 0.5 2.0 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAX92879.1 - 0.0025 16.9 0.2 0.029 13.4 0.0 2.3 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase DivIC PF04977.15 EAX92880.1 - 0.00048 19.8 1.6 0.00048 19.8 1.6 2.1 2 0 0 2 2 2 1 Septum formation initiator HPS3_C PF14763.6 EAX92880.1 - 0.0063 15.9 0.3 0.0084 15.5 0.3 1.1 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HAP1_N PF04849.13 EAX92880.1 - 0.017 14.3 4.6 0.025 13.8 4.6 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Caldesmon PF02029.15 EAX92880.1 - 0.018 13.8 3.0 0.021 13.6 3.0 1.1 1 0 0 1 1 1 0 Caldesmon HSCB_C PF07743.13 EAX92880.1 - 0.027 15.0 7.1 0.19 12.3 2.3 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain APG6_N PF17675.1 EAX92880.1 - 0.03 14.9 7.7 0.051 14.1 7.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EAX92880.1 - 0.21 11.8 7.2 0.075 13.3 3.9 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NRBF2 PF08961.10 EAX92880.1 - 0.22 11.1 4.9 0.21 11.2 3.0 1.8 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2570 PF10828.8 EAX92880.1 - 0.23 11.3 2.7 0.65 9.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) FapA PF03961.13 EAX92880.1 - 0.3 9.6 5.4 0.31 9.6 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PCRF PF03462.18 EAX92880.1 - 0.31 10.9 4.3 0.46 10.3 4.3 1.3 1 0 0 1 1 1 0 PCRF domain DUF724 PF05266.14 EAX92880.1 - 0.4 10.5 4.9 0.59 9.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cas_Cmr5 PF09701.10 EAX92880.1 - 0.57 10.5 3.6 1.5 9.2 0.6 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) ZapB PF06005.12 EAX92880.1 - 0.59 10.6 9.5 0.1 13.0 4.2 2.5 2 1 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 EAX92880.1 - 0.62 11.0 10.3 0.19 12.7 6.9 1.9 2 1 0 2 2 1 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 EAX92880.1 - 0.63 10.1 9.1 0.52 10.4 7.8 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EAX92880.1 - 0.69 10.4 4.9 0.67 10.4 0.8 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 EAX92880.1 - 0.94 10.0 8.9 1.2 9.7 5.5 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 EAX92880.1 - 2 8.5 8.3 0.23 11.6 2.8 2.3 2 2 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 EAX92880.1 - 3.3 7.9 10.5 4.9 7.3 5.7 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF563 PF04577.14 EAX92883.1 - 3.1e-21 76.5 0.8 6.1e-21 75.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ebp2 PF05890.12 EAX92884.1 - 3.3e-15 56.4 18.3 4.5e-15 55.9 18.3 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Brix PF04427.18 EAX92885.1 - 9.5e-27 94.3 0.0 1.1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Vg_Tdu PF07545.14 EAX92885.1 - 0.096 12.5 2.7 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Vestigial/Tondu family DUF4917 PF16263.5 EAX92886.1 - 0.0031 16.9 0.7 0.0037 16.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4917) Vps4_C PF09336.10 EAX92886.1 - 0.0033 17.4 0.0 0.0064 16.5 0.0 1.5 1 1 0 1 1 1 1 Vps4 C terminal oligomerisation domain DUF2443 PF10398.9 EAX92886.1 - 0.017 15.1 1.6 0.02 14.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Ank_2 PF12796.7 EAX92887.1 - 3e-85 280.9 0.6 4.8e-21 75.1 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92887.1 - 1.4e-60 199.3 0.0 6.4e-06 26.4 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EAX92887.1 - 6.1e-59 195.3 0.0 1.4e-08 34.8 0.0 9.1 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92887.1 - 8.5e-54 179.3 0.0 1.8e-10 41.1 0.0 6.2 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92887.1 - 8e-52 167.2 0.0 0.00042 20.5 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Tetrabrachion PF11401.8 EAX92887.1 - 0.022 14.7 0.0 33 4.6 0.0 5.2 7 0 0 7 7 7 0 Tetrabrachion Ank_2 PF12796.7 EAX92888.1 - 3.5e-33 114.0 0.1 5.9e-18 65.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92888.1 - 3.8e-21 74.5 0.0 8.1e-06 26.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX92888.1 - 1.4e-16 60.6 0.0 2.4e-05 24.8 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92888.1 - 2.6e-16 58.0 0.0 0.00014 22.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX92888.1 - 3.7e-13 49.4 0.0 1.1e-05 25.6 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) ENTH PF01417.20 EAX92888.1 - 0.075 13.1 0.2 1.1 9.3 0.1 2.7 1 1 1 2 2 2 0 ENTH domain DUF2795 PF11387.8 EAX92888.1 - 0.11 12.8 0.6 58 4.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) DUP PF00674.18 EAX92888.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 DUP family Ank_2 PF12796.7 EAX92889.1 - 5.3e-84 276.9 63.3 2.9e-16 59.8 5.2 8.0 2 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92889.1 - 5.2e-81 266.1 28.5 1.8e-10 41.1 0.0 12.9 3 1 10 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX92889.1 - 9.6e-81 263.0 21.9 1.2e-07 31.9 0.1 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX92889.1 - 5.7e-58 192.2 16.8 3e-10 40.1 0.2 9.2 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92889.1 - 1.8e-57 184.5 18.3 2.5e-05 24.3 0.0 13.9 14 0 0 14 14 14 11 Ankyrin repeat DUF3447 PF11929.8 EAX92889.1 - 6.8e-37 125.3 8.8 6.8e-37 125.3 8.8 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX92889.1 - 1.3e-05 25.3 0.2 16 5.8 0.0 6.3 4 3 3 7 7 7 0 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX92889.1 - 0.0012 19.0 4.9 79 3.6 0.0 7.1 1 1 7 9 9 9 0 Pleckstrin homology domain YcxB PF14317.6 EAX92889.1 - 0.0016 18.1 0.0 7.8 6.3 0.0 4.1 4 0 0 4 4 4 2 YcxB-like protein HEM4 PF02602.15 EAX92889.1 - 0.036 13.4 1.4 0.5 9.7 0.0 3.4 3 2 0 4 4 4 0 Uroporphyrinogen-III synthase HemD DUF3718 PF12514.8 EAX92889.1 - 0.045 13.9 16.9 4.4 7.5 0.0 8.1 7 4 4 11 11 11 0 Protein of unknown function (DUF3718) Ribosomal_S6 PF01250.17 EAX92889.1 - 4.2 7.7 7.8 39 4.6 0.1 5.2 2 2 4 7 7 7 0 Ribosomal protein S6 Ago_PAZ PF18309.1 EAX92889.1 - 6.7 7.4 7.2 85 3.9 0.1 4.6 2 1 3 5 5 5 0 Argonaute PAZ domain PSP PF04046.16 EAX92891.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PRR20 PF15708.5 EAX92892.1 - 0.39 10.6 4.0 12 5.7 0.1 2.9 1 1 2 3 3 3 0 Proline-rich protein family 20 TrkA_C PF02080.21 EAX92894.1 - 3.8e-12 45.9 0.0 5.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-C domain Voltage_CLC PF00654.20 EAX92894.1 - 1.9e-10 40.5 3.6 2.5e-10 40.2 3.6 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Ank_2 PF12796.7 EAX92895.1 - 2.2e-41 140.3 7.6 1.3e-15 57.7 0.0 5.3 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX92895.1 - 3e-36 123.0 13.1 1.8e-09 37.7 0.1 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92895.1 - 4.3e-33 113.3 5.2 8.3e-10 39.0 0.0 8.3 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92895.1 - 1e-29 99.2 3.6 0.0001 22.4 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX92895.1 - 2.8e-27 93.9 2.7 1.5e-06 28.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 EAX92895.1 - 1.3e-15 57.1 2.5 1.3e-15 57.1 2.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) PV-1 PF06637.11 EAX92896.1 - 0.19 10.5 0.4 0.23 10.3 0.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MFS_1 PF07690.16 EAX92897.1 - 1.1e-06 27.9 12.5 1.6e-06 27.3 12.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DHO_dh PF01180.21 EAX92899.1 - 1.3e-24 87.0 0.2 2.8e-24 85.9 0.2 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4 PF00037.27 EAX92899.1 - 6e-06 25.8 13.9 0.0049 16.6 0.8 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EAX92899.1 - 3.3e-05 23.9 14.6 0.00016 21.7 14.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain DUF561 PF04481.12 EAX92899.1 - 5.4e-05 22.5 0.2 0.0001 21.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Fer4_9 PF13187.6 EAX92899.1 - 0.00018 21.6 12.9 0.00036 20.6 12.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain NMO PF03060.15 EAX92899.1 - 0.0011 18.4 0.3 0.002 17.6 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Fer4_17 PF13534.6 EAX92899.1 - 0.0032 18.0 8.4 0.32 11.6 1.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAX92899.1 - 0.0046 17.0 15.1 0.032 14.3 6.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EAX92899.1 - 0.0056 17.3 14.9 0.031 14.9 15.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAX92899.1 - 0.037 14.1 13.7 0.082 13.0 13.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAX92899.1 - 0.041 14.4 18.6 1.4 9.6 7.8 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain TMP-TENI PF02581.17 EAX92899.1 - 0.13 11.5 0.4 0.26 10.6 0.4 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase FMN_dh PF01070.18 EAX92899.1 - 0.47 9.4 2.3 1.1 8.2 2.4 1.6 1 1 1 2 2 2 0 FMN-dependent dehydrogenase Fer4_2 PF12797.7 EAX92899.1 - 0.56 10.4 18.4 0.76 10.0 5.4 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 EAX92899.1 - 0.81 10.7 13.1 5.4 8.0 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 EAX92899.1 - 2.2 9.4 18.3 2 9.5 7.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain PDEase_I PF00233.19 EAX92900.1 - 4.1e-56 190.4 1.7 7.1e-56 189.6 1.7 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX92900.1 - 1.2e-35 123.1 0.0 2.6e-15 57.2 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 EAX92900.1 - 6.8e-27 94.5 0.0 1.1e-16 61.3 0.0 4.2 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 EAX92900.1 - 3.4e-20 72.7 0.0 5.5e-10 39.7 0.0 3.7 4 0 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 EAX92900.1 - 6.8e-05 22.9 0.6 0.036 14.1 0.1 3.3 2 1 0 2 2 2 2 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 EAX92900.1 - 0.0029 17.8 0.7 0.35 11.0 0.2 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3369) dCache_1 PF02743.18 EAX92900.1 - 0.048 13.4 2.8 2.2 8.0 0.0 3.5 4 0 0 4 4 4 0 Cache domain VPS9 PF02204.18 EAX92902.1 - 0.00088 19.5 0.1 0.0021 18.2 0.1 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 EAX92903.1 - 8e-66 218.6 34.1 2.9e-17 63.0 1.3 6.1 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92903.1 - 2e-63 210.0 14.8 4.1e-10 40.0 0.1 10.1 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX92903.1 - 2.4e-56 185.8 6.7 1.5e-07 31.5 0.1 8.6 7 1 1 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 EAX92903.1 - 5.2e-46 149.3 10.7 4.5e-05 23.5 0.0 10.0 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EAX92903.1 - 6.7e-37 125.1 4.7 1.2e-08 35.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92903.1 - 3.4e-35 119.8 3.6 3.4e-35 119.8 3.6 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX92903.1 - 0.93 9.7 4.1 20 5.4 0.1 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3718) Corazonin PF17308.2 EAX92903.1 - 3.1 8.2 7.1 12 6.2 0.8 2.7 2 0 0 2 2 2 0 Pro-corazonin GDP_Man_Dehyd PF16363.5 EAX92904.1 - 2.1e-62 211.4 0.0 2.8e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAX92904.1 - 6.2e-52 176.4 0.0 7.4e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAX92904.1 - 3.3e-17 62.6 0.0 4.4e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EAX92904.1 - 3.7e-16 59.0 0.1 5.2e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EAX92904.1 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EAX92904.1 - 4.4e-08 32.8 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EAX92904.1 - 5.3e-08 32.3 0.0 7.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EAX92904.1 - 5.3e-06 26.5 0.0 8.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EAX92904.1 - 6.5e-06 25.5 0.0 3.8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EAX92904.1 - 4.1e-05 23.3 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 EAX92904.1 - 0.017 15.0 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EAX92904.1 - 0.079 13.7 0.0 5.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 EAX92904.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF1180 PF06679.12 EAX92905.1 - 0.042 14.3 1.0 0.042 14.3 1.0 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Utp14 PF04615.13 EAX92905.1 - 8.4 4.8 99.8 11 4.5 99.8 1.0 1 0 0 1 1 1 0 Utp14 protein SapC PF07277.11 EAX92906.1 - 0.06 12.9 0.9 0.072 12.7 0.3 1.4 2 0 0 2 2 2 0 SapC Vps23_core PF09454.10 EAX92906.1 - 0.22 11.5 1.0 3.3 7.7 0.4 2.4 1 1 1 2 2 2 0 Vps23 core domain FAS_N PF17828.1 EAX92909.1 - 0.026 14.6 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX92910.1 - 0.03 14.7 0.3 0.04 14.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX92910.1 - 1.4 7.9 2.7 1.5 7.8 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein PapD_N PF00345.20 EAX92911.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX92911.1 - 0.054 13.5 0.2 0.082 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol_B_2 PF03175.13 EAX92912.1 - 1.1e-24 87.2 7.7 4.8e-24 85.1 7.7 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral ResIII PF04851.15 EAX92916.1 - 3.4e-05 23.9 2.2 6.7e-05 23.0 2.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX92916.1 - 0.00029 20.7 0.0 0.00036 20.3 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX92916.1 - 0.00035 20.8 0.0 0.00058 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX92916.1 - 0.00072 19.4 0.8 0.0023 17.8 0.8 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX92916.1 - 0.0061 16.9 0.0 0.008 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX92916.1 - 0.034 13.6 0.1 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAX92916.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAX92916.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX92916.1 - 0.16 12.3 5.3 1.8 8.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) AAA_30 PF13604.6 EAX92916.1 - 0.18 11.5 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3781 PF12636.7 EAX92917.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Ank_2 PF12796.7 EAX92919.1 - 0.06 13.9 0.6 87 3.8 0.0 4.2 2 1 2 4 4 4 0 Ankyrin repeats (3 copies) Ribosomal_S26e PF01283.19 EAX92920.1 - 4.8e-46 155.6 7.3 5.4e-46 155.5 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Sgf11 PF08209.11 EAX92920.1 - 0.013 15.0 0.2 0.013 15.0 0.2 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 EAX92920.1 - 0.027 14.5 0.9 0.67 10.0 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon SRP19 PF01922.17 EAX92920.1 - 0.064 14.2 0.1 0.095 13.7 0.1 1.5 1 1 0 1 1 1 0 SRP19 protein OrfB_Zn_ribbon PF07282.11 EAX92920.1 - 0.49 10.4 6.0 7 6.7 0.5 2.2 1 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF5305 PF17231.2 EAX92921.1 - 0.016 14.6 1.4 0.051 13.0 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5305) AHJR-like PF18743.1 EAX92921.1 - 0.087 12.4 0.4 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 REase_AHJR-like DEAD PF00270.29 EAX92924.1 - 6.8e-32 110.6 0.0 1.3e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX92924.1 - 4.9e-23 81.6 0.1 2.7e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX92924.1 - 2.7e-09 37.3 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EAX92924.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EAX92924.1 - 0.036 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EAX92924.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Flavivirus DEAD domain PFK PF00365.20 EAX92926.1 - 6.2e-45 153.7 0.0 9.2e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase SHMT PF00464.19 EAX92926.1 - 0.079 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase DUF4850 PF16142.5 EAX92926.1 - 0.096 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) SRP54 PF00448.22 EAX92927.1 - 3.6e-71 238.9 0.2 5.7e-71 238.2 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EAX92927.1 - 4.7e-18 65.6 0.8 8.7e-18 64.8 0.1 1.9 2 0 0 2 2 1 1 Signal peptide binding domain SRP54_N PF02881.19 EAX92927.1 - 1.3e-12 47.7 0.4 4.5e-12 46.0 0.4 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EAX92927.1 - 8.6e-06 25.5 0.1 3.1e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAX92927.1 - 0.00015 21.9 0.1 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EAX92927.1 - 0.0023 18.4 0.0 0.017 15.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAX92927.1 - 0.0024 17.2 0.3 0.0062 15.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin SRPRB PF09439.10 EAX92927.1 - 0.0032 16.9 0.3 2.3 7.6 0.1 2.7 2 1 0 3 3 2 2 Signal recognition particle receptor beta subunit SPOUT_MTase PF02590.17 EAX92927.1 - 0.0041 17.1 1.0 1.2 9.1 0.1 3.1 2 1 1 3 3 3 1 Predicted SPOUT methyltransferase AAA_30 PF13604.6 EAX92927.1 - 0.005 16.6 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EAX92927.1 - 0.0063 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 EAX92927.1 - 0.01 15.9 0.0 0.029 14.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EAX92927.1 - 0.011 15.8 0.0 0.042 13.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase 6PF2K PF01591.18 EAX92927.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 EAX92927.1 - 0.015 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EAX92927.1 - 0.031 14.2 0.2 0.094 12.6 0.1 1.8 1 1 0 1 1 1 0 NTPase AAA PF00004.29 EAX92927.1 - 0.05 14.0 1.5 0.75 10.2 0.2 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAX92927.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EAX92927.1 - 0.053 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LpxK PF02606.14 EAX92927.1 - 0.055 12.6 0.1 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase Arf PF00025.21 EAX92927.1 - 0.056 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.9 EAX92927.1 - 0.06 13.1 0.4 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4986 PF16375.5 EAX92927.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function ResIII PF04851.15 EAX92927.1 - 0.11 12.5 0.5 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 EAX92927.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-CCCH_7 PF18586.1 EAX92927.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Thymidylate_kin PF02223.17 EAX92927.1 - 0.25 11.0 1.9 0.65 9.6 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase Saf_2TM PF18303.1 EAX92928.1 - 0.12 12.0 0.1 0.12 12.0 0.1 4.2 2 2 1 4 4 4 0 SAVED-fused 2TM effector domain Bromodomain PF00439.25 EAX92929.1 - 1.8e-21 76.0 0.5 3.9e-21 74.9 0.0 1.8 2 1 0 2 2 2 1 Bromodomain P35 PF02331.15 EAX92929.1 - 0.0066 15.8 0.5 0.0082 15.5 0.5 1.2 1 0 0 1 1 1 1 Apoptosis preventing protein Tom37 PF10568.9 EAX92929.1 - 0.011 16.1 1.2 0.018 15.3 0.3 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein BBP1_N PF15271.6 EAX92929.1 - 0.27 12.0 2.6 0.32 11.8 1.6 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein PG_binding_4 PF12229.8 EAX92929.1 - 1.6 9.1 7.0 4 7.8 3.5 2.6 1 1 2 3 3 3 0 Putative peptidoglycan binding domain Elf1 PF05129.13 EAX92931.1 - 7.1e-22 77.3 3.5 1e-21 76.8 3.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Rubredoxin PF00301.20 EAX92931.1 - 0.0051 16.8 0.6 0.019 15.0 0.2 2.2 2 0 0 2 2 2 1 Rubredoxin Zn_Tnp_IS1595 PF12760.7 EAX92931.1 - 0.027 14.5 1.8 0.044 13.8 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 EAX92931.1 - 5.3 7.6 8.6 2 8.9 0.6 2.8 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 EAX92931.1 - 6.9 7.4 22.8 2.2 9.0 2.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) APG6 PF04111.12 EAX92932.1 - 1.2e-18 67.7 0.1 4.5e-16 59.3 0.1 2.4 1 1 0 1 1 1 1 Apg6 BARA domain Mid2 PF04478.12 EAX92933.1 - 0.0058 16.5 0.4 0.015 15.1 0.4 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.20 EAX92933.1 - 0.0065 16.4 0.7 0.02 14.8 0.2 2.0 2 0 0 2 2 2 1 Syndecan domain Tir_receptor_M PF03549.14 EAX92933.1 - 0.018 15.4 0.1 0.035 14.5 0.1 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Amnionless PF14828.6 EAX92933.1 - 0.083 11.7 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 EAX92933.1 - 0.12 12.3 0.6 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family PsbX PF06596.11 EAX92933.1 - 0.3 11.1 3.2 0.91 9.6 3.2 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Pox_TAA1 PF03295.14 EAX92933.1 - 0.7 9.8 3.2 1.7 8.6 0.0 2.8 4 0 0 4 4 4 0 Poxvirus trans-activator protein A1 C-terminal Stevor PF17410.2 EAX92933.1 - 0.78 9.2 5.7 0.25 10.9 0.8 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4795 PF16043.5 EAX92936.1 - 0.00021 20.9 12.6 0.026 14.1 4.4 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAX92936.1 - 0.0065 16.7 6.2 0.15 12.4 0.3 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1947) AlkA_N PF06029.11 EAX92936.1 - 0.028 14.7 0.0 9.5 6.5 0.0 2.4 2 0 0 2 2 2 0 AlkA N-terminal domain PH_3 PF14593.6 EAX92936.1 - 0.11 12.6 3.2 13 5.9 0.1 3.3 3 0 0 3 3 3 0 PH domain Q_salvage PF10343.9 EAX92937.1 - 1e-93 314.0 0.6 3.9e-93 312.1 0.3 1.8 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family Ank_2 PF12796.7 EAX92938.1 - 4.3e-34 117.0 17.1 6.6e-13 49.1 1.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92938.1 - 1.4e-33 113.8 10.8 1.2e-06 28.7 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 EAX92938.1 - 1.6e-31 108.1 6.0 3.4e-30 103.8 4.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX92938.1 - 2.2e-29 101.4 11.0 2.3e-09 37.6 0.0 7.1 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX92938.1 - 1.5e-26 92.1 9.5 3.9e-08 33.4 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92938.1 - 1.6e-26 89.5 10.3 0.0003 21.0 0.0 8.9 9 0 0 9 9 9 4 Ankyrin repeat Utp21 PF04192.12 EAX92939.1 - 2.4e-21 76.3 0.7 3.5e-21 75.8 0.7 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EAX92939.1 - 3.1e-08 33.8 0.0 0.0036 17.6 0.0 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX92939.1 - 0.00028 20.8 0.0 0.0013 18.6 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EAX92939.1 - 0.0013 19.5 1.5 97 4.1 0.0 5.3 5 1 1 6 6 6 0 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EAX92939.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Not1 PF04054.15 EAX92939.1 - 0.18 10.6 0.4 4.2 6.2 0.1 2.1 1 1 1 2 2 2 0 CCR4-Not complex component, Not1 WD40 PF00400.32 EAX92940.1 - 1.9e-07 31.6 4.2 4.2e-05 24.2 0.1 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX92940.1 - 1.8e-05 24.9 0.1 0.0074 16.6 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 EAX92940.1 - 0.088 11.4 0.0 9.8 4.7 0.0 2.7 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin ADK PF00406.22 EAX92941.1 - 5e-43 146.8 0.0 6.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAX92941.1 - 1e-22 81.0 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EAX92941.1 - 3.2e-14 52.6 0.0 6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EAX92941.1 - 1.3e-06 28.6 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAX92941.1 - 6.1e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAX92941.1 - 0.0025 18.2 0.0 0.0046 17.4 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAX92941.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EAX92941.1 - 0.032 14.2 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EAX92941.1 - 0.042 14.1 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAX92941.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase zf-HIT PF04438.16 EAX92942.1 - 2.7e-10 40.0 9.1 4.2e-10 39.3 9.1 1.3 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 EAX92942.1 - 8.7e-08 31.9 0.1 1.4e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein YL1_C PF08265.11 EAX92942.1 - 0.0099 15.6 1.0 0.02 14.6 1.0 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 EAX92942.1 - 0.14 12.2 14.6 0.25 11.4 14.6 1.4 1 0 0 1 1 1 0 MYND finger ARF7EP_C PF14949.6 EAX92942.1 - 0.66 10.6 8.5 1.5 9.4 8.5 1.6 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Pkinase PF00069.25 EAX92943.1 - 1.3e-21 77.1 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92943.1 - 6e-09 35.6 0.0 7.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX92943.1 - 4.8e-05 22.3 0.0 9.5e-05 21.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAX92943.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX92943.1 - 0.0031 17.2 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX92943.1 - 0.012 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fucosidase_C PF16757.5 EAX92943.1 - 0.09 13.3 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-fucosidase C-terminal domain Ank_2 PF12796.7 EAX92944.1 - 1.7e-68 227.2 4.4 7.7e-15 55.3 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX92944.1 - 6e-53 176.6 1.5 4.9e-09 36.5 0.0 7.6 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX92944.1 - 1.9e-52 173.5 0.2 9.7e-05 22.6 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EAX92944.1 - 1.2e-48 162.5 3.1 1.6e-07 31.4 0.1 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92944.1 - 2.6e-45 147.2 0.3 0.0049 17.3 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat DUF3083 PF11281.8 EAX92944.1 - 0.00099 18.5 0.4 0.14 11.5 0.1 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF3083) HDA2-3 PF11496.8 EAX92944.1 - 0.0016 17.7 1.6 5.9 6.0 0.1 3.3 2 1 1 3 3 3 3 Class II histone deacetylase complex subunits 2 and 3 mTERF PF02536.14 EAX92944.1 - 0.0037 16.3 0.1 0.54 9.1 0.0 3.0 1 1 1 3 3 3 2 mTERF DUF1897 PF09005.10 EAX92944.1 - 0.013 15.0 0.0 90 2.7 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) Response_reg PF00072.24 EAX92944.1 - 0.032 14.4 0.0 1.6e+02 2.5 0.0 5.0 1 1 6 7 7 7 0 Response regulator receiver domain FmdA_AmdA PF03069.15 EAX92944.1 - 0.15 10.9 0.6 4.5 6.0 0.0 2.5 2 1 0 3 3 3 0 Acetamidase/Formamidase family Filament PF00038.21 EAX92945.1 - 7.7e-06 25.7 31.0 0.00097 18.8 5.5 3.5 2 1 1 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 EAX92945.1 - 0.0011 18.9 26.3 0.93 9.5 0.0 4.3 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 EAX92945.1 - 0.0031 17.3 26.7 0.035 13.9 5.9 3.0 1 1 1 2 2 2 1 Family with sequence similarity 184, A and B HWE_HK PF07536.14 EAX92945.1 - 0.017 15.8 9.9 0.29 11.9 0.5 3.8 3 1 1 4 4 3 0 HWE histidine kinase Prominin PF05478.11 EAX92945.1 - 0.086 10.8 27.0 0.0032 15.5 10.0 2.2 1 1 1 2 2 2 0 Prominin RPW8 PF05659.11 EAX92945.1 - 0.13 11.9 16.7 1.3 8.7 1.6 4.5 2 2 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GCS2 PF04107.13 EAX92945.1 - 0.14 11.5 1.0 6.2 6.1 0.0 2.5 1 1 1 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) BLOC1_2 PF10046.9 EAX92945.1 - 0.15 12.4 26.9 0.82 10.0 6.0 5.8 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 EAX92945.1 - 0.28 9.7 7.4 0.31 9.5 0.1 2.4 1 1 2 3 3 3 0 Fusaric acid resistance protein family PTPlike_phytase PF14566.6 EAX92945.1 - 1 9.5 9.6 0.076 13.1 2.9 2.3 2 1 0 2 2 2 0 Inositol hexakisphosphate Baculo_PEP_C PF04513.12 EAX92945.1 - 1 9.4 29.0 3.1 7.9 5.0 4.1 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Erp_C PF06780.11 EAX92945.1 - 1.4 9.0 7.2 2 8.4 3.1 2.6 2 2 0 2 2 2 0 Erp protein C-terminus DUF1664 PF07889.12 EAX92945.1 - 1.8 8.6 27.3 1.8 8.6 6.1 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EAX92945.1 - 1.9 9.2 21.3 2.1 9.1 2.2 4.4 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) SesA PF17107.5 EAX92945.1 - 2 8.6 14.8 0.21 11.8 2.1 3.7 1 1 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CEP63 PF17045.5 EAX92945.1 - 2.7 7.8 29.2 0.039 13.9 5.6 2.9 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Phasin PF05597.11 EAX92945.1 - 2.9 7.9 19.6 0.22 11.5 3.5 3.8 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Allexi_40kDa PF05549.11 EAX92945.1 - 3.7 7.0 23.0 0.96 8.9 2.4 3.7 1 1 3 4 4 4 0 Allexivirus 40kDa protein Exonuc_VII_L PF02601.15 EAX92945.1 - 4 6.9 32.2 1.8e+04 -11.2 32.2 2.7 1 1 0 1 1 0 0 Exonuclease VII, large subunit Muted PF14942.6 EAX92945.1 - 6.4 7.1 27.8 2.9 8.2 6.6 3.8 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Ank_5 PF13857.6 EAX92946.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX92946.1 - 0.043 14.4 0.0 0.058 14.0 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) BBS1 PF14779.6 EAX92947.1 - 9.9e-68 228.3 0.4 6.3e-66 222.4 0.1 2.2 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 DUF2393 PF09624.10 EAX92947.1 - 0.0043 17.1 0.2 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2393) BBS2_Mid PF14783.6 EAX92947.1 - 0.011 15.7 0.0 1.9 8.5 0.0 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nre_C PF04895.12 EAX92947.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal Nre, C-terminal DUF3447 PF11929.8 EAX92948.1 - 1.7e-08 34.3 4.5 1.7e-08 34.3 4.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX92948.1 - 0.0015 19.1 0.0 0.9 10.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX92948.1 - 0.0068 16.8 0.1 7.7 7.4 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeat DUF892 PF05974.12 EAX92948.1 - 0.12 12.4 0.3 0.31 11.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF892) CDKN3 PF05706.12 EAX92949.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) VPS28 PF03997.12 EAX92949.1 - 0.076 12.7 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 VPS28 protein AAA_18 PF13238.6 EAX92949.1 - 0.16 12.5 0.1 0.52 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF563 PF04577.14 EAX92950.1 - 5.4e-34 118.2 0.1 7.5e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) GPS2_interact PF15784.5 EAX92952.1 - 0.022 15.2 0.8 0.03 14.8 0.8 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Shisa PF13908.6 EAX92953.1 - 0.00014 22.1 0.0 0.00018 21.8 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 EAX92953.1 - 0.0076 16.5 0.1 0.017 15.4 0.1 1.7 1 1 1 2 2 2 1 Glycophorin A MBDa PF16564.5 EAX92953.1 - 0.14 12.4 0.9 0.33 11.2 0.5 1.9 2 0 0 2 2 2 0 p55-binding region of Methyl-CpG-binding domain proteins MBD CYYR1 PF10873.8 EAX92953.1 - 1.1 9.7 8.7 6.1 7.3 8.4 2.4 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 Nha1_C PF08619.10 EAX92955.1 - 0.087 12.0 20.9 0.12 11.6 20.9 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus CDC45 PF02724.14 EAX92955.1 - 0.7 8.1 17.0 1 7.6 17.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 EAX92955.1 - 0.91 9.6 9.5 1.9 8.6 9.5 1.5 1 0 0 1 1 1 0 DDHD domain Peptidase_S64 PF08192.11 EAX92955.1 - 0.99 7.8 15.1 1.5 7.2 15.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.18 EAX92955.1 - 2.4 6.4 3.7 4.1 5.7 3.7 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF3807 PF12720.7 EAX92955.1 - 4.8 7.4 21.2 8.4 6.6 21.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 EAX92955.1 - 5.8 6.7 24.2 8.9 6.1 24.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.25 EAX92956.1 - 3.1e-16 59.5 0.8 2.2e-11 43.7 0.8 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92956.1 - 9.6e-07 28.3 0.0 0.0015 17.9 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Aa_trans PF01490.18 EAX92957.1 - 5.7e-39 134.0 37.8 6.4e-39 133.8 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3087 PF11286.8 EAX92957.1 - 1.1 8.8 4.9 0.34 10.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) NPL PF17800.1 EAX92958.1 - 6.6e-14 52.4 0.1 6.6e-14 52.4 0.1 1.5 2 0 0 2 2 2 1 Nucleoplasmin-like domain HGTP_anticodon2 PF12745.7 EAX92958.1 - 0.011 15.3 0.5 0.015 14.8 0.5 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PRKG1_interact PF15898.5 EAX92959.1 - 2.7 9.0 8.5 0.78 10.7 3.2 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Ras PF00071.22 EAX92960.1 - 4.9e-37 127.0 0.0 5.6e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92960.1 - 1.2e-26 93.3 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92960.1 - 1.8e-13 50.3 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX92960.1 - 1.8e-05 24.7 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX92960.1 - 9.6e-05 22.4 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX92960.1 - 0.0012 18.3 0.0 0.0056 16.1 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX92960.1 - 0.0024 17.6 0.4 0.082 12.7 0.4 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAX92960.1 - 0.0027 17.2 0.0 0.004 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX92960.1 - 0.0081 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX92960.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 EAX92960.1 - 0.029 13.9 0.1 1.6 8.2 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EAX92960.1 - 0.029 14.6 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAX92960.1 - 0.033 14.0 0.7 4.3 7.0 0.1 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EAX92960.1 - 0.039 13.1 0.2 0.16 11.1 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 EAX92960.1 - 0.05 13.8 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EAX92960.1 - 0.062 12.8 0.4 0.2 11.2 0.5 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 EAX92960.1 - 0.079 12.7 0.2 0.22 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX92960.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAX92960.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region COMPASS-Shg1 PF05205.12 EAX92961.1 - 0.015 16.0 5.1 0.018 15.8 5.1 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Latarcin PF10279.9 EAX92961.1 - 0.12 12.8 1.4 0.19 12.1 1.3 1.4 1 1 0 1 1 1 0 Latarcin precursor YabA PF06156.13 EAX92961.1 - 0.71 10.5 7.0 0.81 10.4 6.5 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DUF4249 PF14054.6 EAX92962.1 - 0.086 12.5 0.2 0.096 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) FAP PF07174.11 EAX92964.1 - 5.1 6.5 11.5 6.9 6.0 11.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) EF-hand_7 PF13499.6 EAX92965.1 - 2.1e-21 76.2 7.5 5.8e-11 42.7 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX92965.1 - 2.2e-18 64.3 7.9 7e-05 22.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAX92965.1 - 1.6e-16 58.8 5.3 0.0072 16.2 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX92965.1 - 7.3e-09 35.3 6.7 1.5e-05 24.8 0.0 3.7 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 EAX92965.1 - 3.9e-06 27.1 0.4 0.0018 18.5 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EAX92965.1 - 9.9e-06 24.8 10.3 0.00046 19.6 0.0 4.4 5 1 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 EAX92965.1 - 2.2e-05 24.3 7.9 0.45 10.5 0.3 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAX92965.1 - 4.9e-05 23.6 4.7 0.12 12.7 0.1 2.4 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region DUF2624 PF11116.8 EAX92965.1 - 0.044 14.7 0.1 0.19 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) p25-alpha PF05517.12 EAX92965.1 - 0.073 13.2 0.5 3.7 7.7 0.1 2.3 1 1 1 2 2 2 0 p25-alpha EF-hand_11 PF08976.11 EAX92965.1 - 0.18 12.7 2.3 3.7 8.5 0.3 2.8 1 1 2 3 3 3 0 EF-hand domain Caleosin PF05042.13 EAX92965.1 - 0.19 11.6 1.0 59 3.5 0.1 2.9 1 1 2 3 3 3 0 Caleosin related protein APG6 PF04111.12 EAX92966.1 - 2e-13 50.7 0.4 1.2e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Apg6 BARA domain T6PP_N PF18572.1 EAX92966.1 - 0.82 9.5 6.0 0.82 9.5 0.3 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Ald_Xan_dh_C2 PF02738.18 EAX92968.1 - 2.5e-187 623.7 0.1 3.6e-187 623.2 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EAX92968.1 - 5.9e-33 114.0 0.0 1.3e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EAX92968.1 - 2.6e-30 105.0 0.1 5.9e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EAX92968.1 - 1.3e-29 102.1 0.2 2.8e-29 100.9 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 EAX92968.1 - 1e-27 96.3 0.0 5.8e-27 93.9 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 EAX92968.1 - 6.5e-05 22.8 0.1 0.00023 21.0 0.1 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HTH_24 PF13412.6 EAX92968.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DHODB_Fe-S_bind PF10418.9 EAX92968.1 - 0.081 12.7 1.0 0.22 11.4 1.0 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Sigma70_r4_2 PF08281.12 EAX92968.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 60KD_IMP PF02096.20 EAX92969.1 - 0.01 15.7 0.6 0.017 15.0 0.6 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein SelB-wing_3 PF09107.11 EAX92971.1 - 0.2 11.3 1.0 7.2 6.3 0.0 2.9 4 0 0 4 4 4 0 Elongation factor SelB, winged helix DUF4795 PF16043.5 EAX92972.1 - 0.0079 15.8 22.6 0.81 9.2 4.7 3.5 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) PaREP1 PF05942.11 EAX92972.1 - 0.054 13.4 7.9 1.6 8.7 0.6 2.4 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family AlkA_N PF06029.11 EAX92972.1 - 0.11 12.7 0.0 28 5.0 0.0 2.5 2 0 0 2 2 2 0 AlkA N-terminal domain Peptidase_U57 PF05582.12 EAX92972.1 - 0.36 10.1 3.6 5.4 6.2 0.6 2.3 1 1 1 2 2 2 0 YabG peptidase U57 Pox_A32 PF04665.12 EAX92974.1 - 5e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX92974.1 - 0.0047 16.9 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX92974.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX92974.1 - 0.085 13.1 1.7 0.2 11.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) NLPC_P60 PF00877.19 EAX92977.1 - 1.8e-13 50.5 0.2 2.3e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 EAX92977.1 - 0.13 12.6 0.1 0.26 11.6 0.0 1.5 2 0 0 2 2 2 0 Lecithin retinol acyltransferase V-ATPase_G_2 PF16999.5 EAX92978.1 - 0.0054 17.1 5.5 0.0054 17.1 5.5 7.8 8 2 1 9 9 9 2 Vacuolar (H+)-ATPase G subunit Pkinase PF00069.25 EAX92980.1 - 1.3e-27 96.8 0.1 1.5e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX92980.1 - 7.7e-16 58.1 0.0 8.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX92980.1 - 3.9e-07 29.7 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX92980.1 - 0.0015 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX92980.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EAX92980.1 - 0.038 13.0 0.6 0.058 12.5 0.6 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PSP PF04046.16 EAX92981.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX92982.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX92983.1 - 0.035 14.6 0.6 0.072 13.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX92984.1 - 8.8e-31 105.8 11.4 8.8e-31 105.8 11.4 3.3 5 0 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX92984.1 - 0.031 14.0 0.2 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX92984.1 - 5.3 7.0 8.8 2.6 8.0 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF240) Gly_rich PF12810.7 EAX92985.1 - 1.5e-20 74.2 16.0 1.7e-20 74.0 16.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX92986.1 - 3e-55 187.8 41.2 4.3e-55 187.3 41.2 1.2 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX92987.1 - 4.4e-54 184.0 36.9 6.1e-54 183.5 36.9 1.2 1 0 0 1 1 1 1 Glycine rich protein VraX PF17412.2 EAX92988.1 - 7.2 6.3 8.5 1 9.1 0.3 3.9 3 0 0 3 3 3 0 Family of unknown function RST PF12174.8 EAX92988.1 - 9.8 6.2 9.7 12 5.9 0.5 3.8 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Ras PF00071.22 EAX92991.1 - 7.4e-35 119.9 0.1 8.8e-35 119.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX92991.1 - 4.8e-25 88.1 0.0 7.2e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX92991.1 - 1.7e-11 43.9 0.1 2.5e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX92991.1 - 1.7e-06 27.7 0.2 9.4e-06 25.3 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX92991.1 - 5.1e-06 26.6 0.1 6.9e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX92991.1 - 1.2e-05 24.8 0.1 1.8e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX92991.1 - 1.9e-05 24.7 0.1 0.078 12.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EAX92991.1 - 3.9e-05 23.2 0.0 0.0001 21.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EAX92991.1 - 4.1e-05 24.0 0.1 0.0008 19.8 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EAX92991.1 - 0.00039 19.9 0.1 0.00051 19.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 EAX92991.1 - 0.0019 17.4 0.4 0.018 14.2 0.4 2.0 1 1 0 1 1 1 1 NB-ARC domain MMR_HSR1_Xtn PF16897.5 EAX92991.1 - 0.0023 17.9 0.3 0.011 15.8 0.2 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_23 PF13476.6 EAX92991.1 - 0.0044 17.6 0.4 0.0088 16.6 0.3 1.4 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EAX92991.1 - 0.009 15.4 0.0 0.022 14.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 EAX92991.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EAX92991.1 - 0.02 15.2 0.0 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAX92991.1 - 0.028 14.4 0.1 0.04 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAX92991.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EAX92991.1 - 0.047 13.2 0.4 0.78 9.2 0.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 EAX92991.1 - 0.048 14.2 0.2 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter MnmE_helical PF12631.7 EAX92991.1 - 0.055 13.6 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain NACHT PF05729.12 EAX92991.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EAX92991.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 EAX92991.1 - 0.083 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Septin ATPase PF06745.13 EAX92991.1 - 0.11 11.8 1.3 0.36 10.1 0.4 2.0 1 1 1 2 2 2 0 KaiC AAA_29 PF13555.6 EAX92991.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EAX92991.1 - 0.15 11.0 0.1 4.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ank_2 PF12796.7 EAX92992.1 - 9.1e-60 199.2 30.1 1.1e-15 58.0 0.1 8.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX92992.1 - 2.6e-58 192.0 27.7 6e-07 29.6 0.4 12.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.6 EAX92992.1 - 2.9e-52 174.4 16.4 2.1e-09 37.7 0.0 11.2 8 2 4 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX92992.1 - 1.9e-51 166.0 23.7 1e-05 25.5 0.0 14.6 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 EAX92992.1 - 1.8e-49 165.2 22.8 6.4e-07 29.5 0.1 11.0 7 2 4 11 11 11 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX92992.1 - 9.6e-20 70.3 0.7 9.6e-20 70.3 0.7 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3447) DUF249 PF03158.13 EAX92992.1 - 0.1 12.3 2.9 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Multigene family 530 protein PDEase_I PF00233.19 EAX92993.1 - 2.3e-77 259.9 4.5 2.3e-77 259.9 4.5 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX92993.1 - 3.5e-24 85.9 0.0 4.9e-13 49.9 0.0 4.9 5 1 0 5 5 5 4 GAF domain GAF_2 PF13185.6 EAX92993.1 - 5.9e-24 84.9 0.0 6.6e-07 29.7 0.0 4.5 4 1 0 4 4 4 4 GAF domain GAF_3 PF13492.6 EAX92993.1 - 2.7e-12 47.1 0.0 5.5e-06 26.8 0.0 4.1 4 0 0 4 4 4 2 GAF domain SpoVT_C PF15714.5 EAX92993.1 - 0.00029 20.9 0.2 0.0068 16.5 0.0 3.1 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 EAX92993.1 - 0.0005 20.3 1.4 0.38 10.9 0.1 4.3 3 2 0 3 3 3 1 Domain of unknown function (DUF3369) HD PF01966.22 EAX92993.1 - 0.11 12.7 0.1 0.53 10.5 0.1 2.2 1 1 0 1 1 1 0 HD domain Ter PF05472.11 EAX92994.1 - 0.021 13.8 0.0 0.023 13.7 0.0 1.0 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Tho2 PF11262.8 EAX92995.1 - 0.055 12.7 2.9 0.062 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Meiosis_expr PF15163.6 EAX92995.1 - 0.079 13.6 0.9 0.13 13.0 0.4 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX92995.1 - 0.38 10.7 8.3 0.14 12.0 2.8 2.8 3 1 0 3 3 3 0 Spo12 family EpuA PF11772.8 EAX92996.1 - 0.0069 16.1 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta T5orf172 PF10544.9 EAX92997.1 - 0.0001 22.8 0.3 0.00021 21.8 0.3 1.5 1 0 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX92998.1 - 1.9e-138 459.7 12.6 5.3e-138 458.3 12.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX92998.1 - 0.092 13.2 0.3 0.69 10.4 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 EAX92998.1 - 0.48 10.8 4.2 10 6.5 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAX92998.1 - 0.72 10.4 4.6 4.2 7.9 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX92999.1 - 3.7e-07 30.6 0.1 9.4e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX92999.1 - 0.0047 16.8 1.0 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX93000.1 - 4.5e-156 517.4 14.0 5.6e-156 517.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX93001.1 - 2.8e-05 24.1 3.0 2.8e-05 24.1 3.0 5.2 7 1 1 8 8 8 1 Phage tail repeat like DUF4795 PF16043.5 EAX93001.1 - 0.043 13.4 16.8 0.75 9.4 10.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Transposase_24 PF03004.14 EAX93001.1 - 3.4 7.8 7.9 16 5.6 0.6 3.1 3 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) DUF1493 PF07377.12 EAX93002.1 - 0.051 14.0 0.9 0.1 13.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX93003.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX93004.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Kinesin PF00225.23 EAX93005.1 - 1.4e-76 257.6 6.8 1.4e-76 257.6 6.8 3.1 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAX93005.1 - 6.6e-21 74.8 0.1 6.6e-21 74.8 0.1 2.8 3 1 0 3 3 3 1 Microtubule binding Tai4 PF16695.5 EAX93006.1 - 0.048 14.2 0.6 0.52 10.9 0.2 2.6 2 1 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein ERCC3_RAD25_C PF16203.5 EAX93006.1 - 0.054 12.7 0.6 0.097 11.9 0.6 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Spc7 PF08317.11 EAX93007.1 - 4.2e-06 25.9 59.5 0.00045 19.2 6.1 3.6 1 1 3 4 4 4 3 Spc7 kinetochore protein FPP PF05911.11 EAX93007.1 - 0.00025 19.4 7.0 0.00025 19.4 7.0 2.4 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil FapA PF03961.13 EAX93007.1 - 0.0027 16.4 5.0 0.0027 16.4 5.0 3.9 1 1 2 3 3 2 1 Flagellar Assembly Protein A Filament PF00038.21 EAX93007.1 - 0.0035 17.0 51.4 0.027 14.0 7.6 4.2 1 1 3 4 4 4 2 Intermediate filament protein DUF4200 PF13863.6 EAX93007.1 - 0.006 17.0 4.0 0.006 17.0 4.0 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF4200) PspA_IM30 PF04012.12 EAX93007.1 - 0.0079 15.8 27.0 0.01 15.4 8.2 4.2 1 1 1 3 3 3 2 PspA/IM30 family DUF3584 PF12128.8 EAX93007.1 - 0.0081 13.7 51.2 0.052 11.1 30.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EAX93007.1 - 0.0086 16.2 59.5 0.014 15.5 17.8 3.6 1 1 1 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EAX93007.1 - 0.018 15.2 4.5 0.018 15.2 4.5 5.0 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 EAX93007.1 - 0.023 14.9 3.3 0.023 14.9 3.3 4.7 1 1 4 5 5 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EAX93007.1 - 0.063 13.9 0.9 0.063 13.9 0.9 7.0 4 2 2 6 6 6 0 SlyX Atg14 PF10186.9 EAX93007.1 - 0.15 11.1 56.5 0.092 11.8 3.0 3.8 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 EAX93007.1 - 0.16 12.3 0.2 0.16 12.3 0.2 6.1 3 2 1 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EAX93007.1 - 0.52 10.4 37.8 1.2 9.2 3.0 5.2 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EAX93007.1 - 0.87 9.7 57.0 0.92 9.6 14.7 5.6 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 EAX93007.1 - 1 9.7 54.1 0.17 12.2 3.8 4.6 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 EAX93007.1 - 1.2 8.4 50.8 0.87 8.8 0.3 5.8 1 1 5 6 6 6 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 EAX93007.1 - 1.5 7.6 59.0 0.83 8.5 2.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 EAX93007.1 - 2.1 8.1 54.5 2.2 8.0 4.6 4.2 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EAX93007.1 - 2.1 7.6 56.6 0.29 10.5 16.8 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EAX93007.1 - 2.4 7.4 37.1 0.24 10.7 4.7 3.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EAX93007.1 - 5.4 7.6 41.8 0.5 10.9 0.4 5.5 1 1 3 4 4 3 0 Syntaxin 6, N-terminal HMMR_N PF15905.5 EAX93007.1 - 5.5 6.4 63.2 0.4 10.1 24.0 3.5 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF2203 PF09969.9 EAX93007.1 - 5.8 7.7 30.5 6.1 7.6 1.5 5.0 2 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 EAX93007.1 - 7.2 6.6 57.6 0.053 13.5 5.3 4.9 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 EAX93007.1 - 8.2 6.8 52.6 6.5 7.2 9.9 3.6 1 1 2 3 3 3 0 Fez1 Ank_2 PF12796.7 EAX93008.1 - 9.3e-18 64.6 1.4 3.5e-15 56.3 0.0 2.8 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93008.1 - 4.1e-15 55.9 0.3 2.6e-06 27.8 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93008.1 - 1.4e-14 53.9 0.0 3.4e-08 33.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93008.1 - 9e-13 47.2 0.7 3.8e-07 29.9 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX93008.1 - 1.6e-09 37.8 0.1 1.4e-06 28.5 0.1 3.2 2 0 0 2 2 2 1 Ankyrin repeat DUF1296 PF06972.11 EAX93008.1 - 0.00028 20.9 4.3 0.9 9.7 0.1 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1296) Med4 PF10018.9 EAX93008.1 - 0.062 13.0 0.9 0.12 12.0 0.9 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 VGPC1_C PF16799.5 EAX93008.1 - 0.085 12.9 1.0 0.21 11.6 1.0 1.6 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Carboxyl_trans PF01039.22 EAX93008.1 - 0.16 10.5 0.1 0.26 9.9 0.1 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain Spc29 PF17082.5 EAX93008.1 - 0.35 10.7 5.0 0.54 10.0 0.4 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Ada3 PF10198.9 EAX93008.1 - 0.56 10.4 2.7 0.52 10.5 1.3 1.6 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 KilA-N PF04383.13 EAX93011.1 - 6.5e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain MAAL_N PF05034.13 EAX93011.1 - 0.04 13.6 0.1 0.043 13.4 0.1 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus PIN_8 PF18476.1 EAX93013.1 - 0.021 14.7 1.4 0.024 14.5 1.4 1.0 1 0 0 1 1 1 0 PIN like domain GET2 PF08690.10 EAX93013.1 - 0.31 10.7 7.5 0.31 10.7 7.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Synaptobrevin PF00957.21 EAX93016.1 - 0.00084 19.1 0.4 0.0011 18.8 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.9 EAX93016.1 - 0.09 12.7 0.2 0.097 12.5 0.2 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3574 PF12098.8 EAX93017.1 - 0.11 12.3 0.7 0.18 11.6 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) DUF4107 PF13389.6 EAX93020.1 - 0.1 12.7 0.2 0.15 12.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) AbiJ_NTD4 PF18863.1 EAX93022.1 - 0.024 15.1 0.1 0.034 14.6 0.1 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Csm1_N PF18504.1 EAX93023.1 - 0.00049 20.4 4.7 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 Csm1 N-terminal domain DHR10 PF18595.1 EAX93023.1 - 0.00067 19.7 8.7 0.002 18.2 8.7 1.7 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 EAX93023.1 - 0.002 18.5 3.5 0.0038 17.6 3.5 1.5 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EAX93023.1 - 0.0047 15.9 5.6 0.0048 15.8 5.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX93023.1 - 0.0062 16.4 6.0 0.0073 16.1 1.6 2.9 1 1 2 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 EAX93023.1 - 0.0084 15.6 7.7 0.0084 15.6 7.7 1.4 1 1 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 EAX93023.1 - 0.0087 16.1 2.9 3.6 7.8 0.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor FPP PF05911.11 EAX93023.1 - 0.0096 14.2 6.9 0.011 14.0 6.9 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF641 PF04859.12 EAX93023.1 - 0.014 15.8 4.4 0.014 15.8 4.4 1.5 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) HemX PF04375.14 EAX93023.1 - 0.017 14.4 2.5 0.02 14.2 2.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GNT-I PF03071.15 EAX93023.1 - 0.02 13.7 0.8 0.026 13.3 0.8 1.1 1 0 0 1 1 1 0 GNT-I family ADIP PF11559.8 EAX93023.1 - 0.021 14.9 6.8 0.091 12.8 7.0 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EAX93023.1 - 0.023 14.5 2.0 0.023 14.5 2.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EAX93023.1 - 0.048 11.6 2.5 0.062 11.2 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EAX93023.1 - 0.05 12.7 4.4 0.056 12.5 4.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1672 PF07901.11 EAX93023.1 - 0.054 12.8 1.2 0.075 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Phage_GP20 PF06810.11 EAX93023.1 - 0.072 12.9 6.9 1.4 8.7 3.7 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 EAX93023.1 - 0.12 12.6 11.0 0.17 12.1 11.0 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EAX93023.1 - 0.18 11.9 1.4 0.28 11.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 EAX93023.1 - 0.19 11.0 6.7 0.21 10.9 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 EAX93023.1 - 0.23 10.7 4.0 0.3 10.3 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 EAX93023.1 - 0.44 11.1 5.6 0.67 10.5 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EAX93023.1 - 0.56 10.3 11.2 0.74 9.9 11.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EAX93023.1 - 7.7 7.2 9.1 4.5 8.0 5.1 2.5 2 1 0 2 2 1 0 SlyX Kelch_1 PF01344.25 EAX93024.1 - 9e-23 79.6 2.4 2.2e-05 23.9 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EAX93024.1 - 2.2e-22 78.8 3.9 2.7e-10 40.1 0.0 5.4 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX93024.1 - 5.6e-13 48.7 3.3 0.00086 19.5 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EAX93024.1 - 1.2e-12 47.8 2.8 2.8e-05 24.3 0.0 6.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EAX93024.1 - 1.3e-12 47.3 3.0 0.0069 16.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAX93024.1 - 3.1e-12 45.9 2.9 0.0016 18.4 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Spc7 PF08317.11 EAX93025.1 - 1.8e-06 27.1 651.0 0.022 13.6 26.4 22.2 1 1 23 24 24 24 14 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EAX93025.1 - 2.2e-05 24.5 7.1 2.2e-05 24.5 7.1 34.7 8 8 20 33 33 33 1 TolA binding protein trimerisation KASH_CCD PF14662.6 EAX93025.1 - 3.3e-05 23.8 37.8 3.3e-05 23.8 37.8 18.4 1 1 17 18 18 18 7 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 EAX93025.1 - 9.5e-05 22.4 17.7 9.5e-05 22.4 17.7 26.6 6 5 17 27 27 27 9 Laminin Domain II IFT57 PF10498.9 EAX93025.1 - 0.0012 17.9 45.2 0.0012 17.9 45.2 19.3 1 1 16 19 19 19 7 Intra-flagellar transport protein 57 CALCOCO1 PF07888.11 EAX93025.1 - 0.0019 17.2 37.7 0.0019 17.2 37.7 13.6 1 1 13 14 14 14 7 Calcium binding and coiled-coil domain (CALCOCO1) like Syntaxin-6_N PF09177.11 EAX93025.1 - 0.0089 16.6 8.5 0.0089 16.6 8.5 29.1 3 2 24 27 27 27 6 Syntaxin 6, N-terminal PKcGMP_CC PF16808.5 EAX93025.1 - 0.025 14.4 0.4 0.025 14.4 0.4 35.2 36 3 2 38 38 38 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 EAX93026.1 - 2.7e-06 26.5 634.2 0.016 14.1 32.1 21.2 1 1 22 24 24 24 13 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EAX93026.1 - 1.1e-05 25.6 70.5 6.6e-05 23.1 29.4 25.9 2 2 22 24 24 24 7 Tropomyosin like ATG16 PF08614.11 EAX93026.1 - 8e-05 22.9 45.6 8e-05 22.9 45.6 23.7 1 1 22 23 23 23 8 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EAX93026.1 - 0.00098 19.1 47.8 0.0017 18.3 24.6 44.4 5 4 37 45 45 45 12 TATA element modulatory factor 1 DNA binding ERM PF00769.19 EAX93026.1 - 0.0012 18.7 46.7 0.0012 18.7 46.7 17.8 1 1 18 20 20 20 4 Ezrin/radixin/moesin family GAS PF13851.6 EAX93026.1 - 0.0014 18.1 28.5 0.0014 18.1 28.5 22.5 1 1 23 24 24 24 12 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EAX93026.1 - 0.0026 17.6 44.1 0.0026 17.6 44.1 20.7 1 1 16 18 18 18 5 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 EAX93026.1 - 0.0045 17.5 556.7 0.065 13.7 27.5 20.5 1 1 19 20 20 20 6 Fez1 CENP-F_leu_zip PF10473.9 EAX93026.1 - 0.0045 17.0 17.7 0.0045 17.0 17.7 24.0 1 1 22 24 24 24 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EAX93026.1 - 0.0049 17.0 26.8 0.0049 17.0 26.8 29.2 2 2 24 29 29 29 7 Afadin- and alpha -actinin-Binding HCBP_related PF06594.11 EAX93029.1 - 0.7 9.9 3.6 1.5 8.8 3.6 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain Methyltransf_25 PF13649.6 EAX93030.1 - 9.6e-11 42.3 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX93030.1 - 4.8e-10 39.9 0.0 9.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX93030.1 - 5.3e-09 36.7 0.1 9.8e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX93030.1 - 2.3e-08 34.0 0.2 3.3e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAX93030.1 - 0.0034 16.9 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ank_2 PF12796.7 EAX93031.1 - 1.3e-80 266.0 0.0 1.2e-15 57.9 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93031.1 - 1.7e-42 142.0 0.0 6.9e-05 23.1 0.0 8.3 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EAX93031.1 - 3.1e-41 139.2 0.0 5.8e-10 39.5 0.0 5.8 3 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93031.1 - 8.3e-37 121.0 0.0 0.00026 21.2 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX93031.1 - 4.4e-36 122.5 0.0 4.2e-06 26.9 0.0 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) DUF5049 PF16468.5 EAX93031.1 - 0.024 14.5 0.1 96 3.0 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF5049) DUF3083 PF11281.8 EAX93031.1 - 0.028 13.8 0.0 1.8 7.8 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3083) Sfi1 PF08457.10 EAX93032.1 - 0.0015 17.1 29.0 0.0015 17.1 29.0 4.0 1 1 3 4 4 4 3 Sfi1 spindle body protein ComX PF05952.12 EAX93032.1 - 0.0097 15.8 0.1 0.034 14.1 0.1 1.9 1 0 0 1 1 1 1 Bacillus competence pheromone ComX Ribosomal_L6 PF00347.23 EAX93033.1 - 8.5e-10 39.2 0.9 0.00042 20.9 0.0 3.1 2 1 1 3 3 3 3 Ribosomal protein L6 Arf PF00025.21 EAX93035.1 - 7.8e-51 172.0 0.0 8.7e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAX93035.1 - 9e-10 38.2 5.1 6.9e-08 32.0 1.6 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAX93035.1 - 5.3e-08 32.5 0.1 6.6e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX93035.1 - 1.4e-05 24.5 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EAX93035.1 - 2.6e-05 23.9 0.0 3.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX93035.1 - 8.5e-05 22.8 0.1 0.00013 22.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX93035.1 - 0.0007 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EAX93035.1 - 0.011 15.3 1.1 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cas_Csx8 PF09657.10 EAX93035.1 - 0.035 13.1 0.1 0.038 13.0 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) MeaB PF03308.16 EAX93035.1 - 0.25 10.3 0.1 1.3 8.0 0.0 2.2 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EAX93036.1 - 1.9e-71 239.1 0.1 2.1e-71 238.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX93036.1 - 3e-15 56.5 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAX93036.1 - 1.3e-13 50.8 0.0 1.5e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EAX93036.1 - 7.8e-13 48.3 0.0 8.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EAX93036.1 - 1.6e-10 40.7 0.1 6.8e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX93036.1 - 7.8e-09 35.2 0.0 9.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX93036.1 - 5e-05 23.4 0.0 8.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAX93036.1 - 0.0059 15.9 0.1 0.0081 15.5 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase MeaB PF03308.16 EAX93036.1 - 0.17 10.9 0.0 0.54 9.2 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB V-ATPase_H_N PF03224.14 EAX93037.1 - 0.0039 16.5 11.7 0.079 12.2 5.4 3.2 1 1 1 3 3 3 2 V-ATPase subunit H MA3 PF02847.17 EAX93037.1 - 0.26 11.3 6.7 1.1 9.3 0.1 4.3 4 2 0 4 4 4 0 MA3 domain FOP_dimer PF09398.10 EAX93038.1 - 0.045 14.0 0.4 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Bromodomain PF00439.25 EAX93039.1 - 2.1e-17 63.0 1.7 4.9e-17 61.8 1.7 1.6 1 0 0 1 1 1 1 Bromodomain PC4 PF02229.16 EAX93040.1 - 2.2e-18 65.6 0.8 2.9e-18 65.2 0.8 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Mem_trans PF03547.18 EAX93041.1 - 8.4e-17 60.6 21.6 2.4e-16 59.1 10.0 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF5106 PF17127.4 EAX93043.1 - 0.038 14.3 1.1 0.047 14.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Interfer-bind PF09294.10 EAX93043.1 - 0.13 12.6 3.0 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Coiled-coil_56 PF09813.9 EAX93043.1 - 0.24 11.5 2.4 2.2 8.4 1.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF4108 PF13390.6 EAX93047.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX93048.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX93048.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX93048.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX93049.1 - 0.00022 20.8 4.2 0.00038 20.0 4.1 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX93049.1 - 0.0037 17.3 0.8 0.0079 16.2 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX93049.1 - 0.01 15.4 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX93049.1 - 0.056 13.7 1.5 0.15 12.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAX93050.1 - 4.1e-149 494.7 10.8 5.1e-149 494.4 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX93050.1 - 0.019 15.4 1.4 0.052 14.0 0.1 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX93050.1 - 0.029 14.8 5.6 0.65 10.5 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX93051.1 - 2.8e-05 24.1 0.4 2.8e-05 24.1 0.4 4.4 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX93051.1 - 0.066 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX93051.1 - 0.11 13.0 2.9 0.19 12.2 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF445 PF04286.12 EAX93051.1 - 0.29 10.9 8.2 0.41 10.4 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1493 PF07377.12 EAX93052.1 - 0.037 14.5 0.7 0.078 13.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX93053.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat UPF0242 PF06785.11 EAX93054.1 - 0.0039 17.3 10.1 0.0051 16.9 10.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 EAX93054.1 - 0.0067 16.8 5.6 0.014 15.7 5.6 1.6 1 0 0 1 1 1 1 Syntaxin-like protein Psb28 PF03912.14 EAX93054.1 - 0.032 14.5 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Psb28 protein Ribosomal_60s PF00428.19 EAX93055.1 - 5.9e-17 62.0 18.3 7.4e-17 61.7 18.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1456 PF07308.13 EAX93055.1 - 0.018 15.3 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Metallophos_3 PF14582.6 EAX93055.1 - 0.037 13.4 0.2 0.039 13.3 0.2 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PepSY_2 PF13670.6 EAX93055.1 - 2.1 8.4 11.4 1.4 9.0 0.2 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF563 PF04577.14 EAX93056.1 - 4.3e-20 72.8 0.3 8.6e-20 71.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF1722 PF08349.11 EAX93057.1 - 0.0058 16.9 3.2 0.012 15.9 3.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1722) DUF1664 PF07889.12 EAX93057.1 - 0.014 15.4 1.4 0.014 15.4 1.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_lysis PF03245.13 EAX93057.1 - 0.019 15.1 1.4 0.019 15.1 1.4 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF4200 PF13863.6 EAX93057.1 - 0.019 15.3 18.4 0.023 15.1 17.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 EAX93057.1 - 0.025 14.6 14.4 0.3 11.1 0.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DDE_Tnp_IS240 PF13610.6 EAX93057.1 - 0.19 11.9 3.8 0.088 13.0 0.9 1.8 1 1 1 2 2 2 0 DDE domain HAUS-augmin3 PF14932.6 EAX93057.1 - 0.21 11.2 13.4 0.032 13.8 1.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DegS PF05384.11 EAX93057.1 - 0.38 10.2 14.6 0.024 14.2 2.2 2.1 2 0 0 2 2 2 0 Sensor protein DegS DUF2433 PF10360.9 EAX93057.1 - 0.6 10.2 7.2 1.3 9.2 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) G-gamma PF00631.22 EAX93057.1 - 2.4 8.2 6.0 1.2 9.2 2.3 2.5 2 1 1 3 3 2 0 GGL domain Csm1_N PF18504.1 EAX93057.1 - 3.2 8.1 12.5 0.34 11.3 4.7 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain HIP1_clath_bdg PF16515.5 EAX93057.1 - 4.7 7.9 14.4 2.2 8.9 6.7 2.7 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-Q PF13094.6 EAX93057.1 - 5.1 7.3 12.3 15 5.8 11.5 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.15 EAX93057.1 - 7.6 6.0 12.7 13 5.2 12.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit CorA PF01544.18 EAX93057.1 - 9 5.5 10.4 14 4.9 10.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UBX PF00789.20 EAX93058.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 UBX domain SPG4 PF17325.2 EAX93058.1 - 0.041 15.0 1.5 0.067 14.3 1.5 1.2 1 0 0 1 1 1 0 Stationary phase protein 4 PRAP PF15314.6 EAX93058.1 - 0.099 13.1 4.6 0.25 11.8 4.6 1.7 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine SH3_1 PF00018.28 EAX93059.1 - 2.4e-16 59.1 0.5 8.1e-12 44.6 0.1 3.0 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EAX93059.1 - 2.8e-16 59.1 0.3 2.5e-12 46.4 0.0 2.5 2 1 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EAX93059.1 - 1.2e-15 56.9 0.2 4.9e-12 45.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain IDO PF01231.18 EAX93059.1 - 0.0016 17.3 0.1 0.0027 16.5 0.1 1.4 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF5424 PF17462.2 EAX93059.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5424) SbsC_C PF18058.1 EAX93059.1 - 0.098 12.9 4.1 0.64 10.3 2.4 2.3 2 0 0 2 2 2 0 SbsC C-terminal domain FCH PF00611.23 EAX93059.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF148 PF02520.17 EAX93059.1 - 0.19 11.8 6.1 0.32 11.1 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 CHASE3 PF05227.13 EAX93059.1 - 0.22 11.4 2.9 1.4 8.8 2.9 2.1 1 1 0 1 1 1 0 CHASE3 domain BAR_3 PF16746.5 EAX93059.1 - 0.24 11.1 5.8 0.74 9.5 5.2 2.1 1 1 0 1 1 1 0 BAR domain of APPL family DUF5344 PF17279.2 EAX93059.1 - 0.99 10.0 5.0 0.5 11.0 0.7 2.7 2 2 1 3 3 3 0 Family of unknown function (DUF5344) KxDL PF10241.9 EAX93059.1 - 1.8 8.9 7.6 0.51 10.6 1.5 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein Transposase_mut PF00872.18 EAX93060.1 - 0.00089 18.2 0.3 0.001 18.0 0.3 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX93060.1 - 0.019 14.9 0.2 0.023 14.6 0.2 1.1 1 0 0 1 1 1 0 Vta1 like DDE_Tnp_ISL3 PF01610.17 EAX93060.1 - 0.038 13.7 0.3 1.3 8.7 0.0 1.8 1 1 1 2 2 2 0 Transposase MULE PF10551.9 EAX93060.1 - 0.15 12.5 0.4 0.4 11.1 0.1 1.9 2 0 0 2 2 2 0 MULE transposase domain FAR1 PF03101.15 EAX93061.1 - 0.013 16.2 0.1 0.026 15.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF4107 PF13389.6 EAX93062.1 - 4.8e-66 221.9 14.1 1.1e-64 217.5 14.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX93062.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta PTR PF12789.7 EAX93064.1 - 4.2e-07 29.9 3.2 4.2e-07 29.9 3.2 5.9 5 2 0 5 5 5 2 Phage tail repeat like DNA_pol_B_2 PF03175.13 EAX93066.1 - 1.2e-12 47.4 2.0 1.9e-11 43.5 1.5 2.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX93066.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DDR PF08841.10 EAX93068.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX93068.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Gly_rich PF12810.7 EAX93069.1 - 1.6e-50 172.3 33.4 2e-50 172.0 33.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Beta_helix PF13229.6 EAX93070.1 - 1.3e-29 103.1 42.8 1.9e-13 50.6 5.0 5.2 2 1 3 5 5 5 4 Right handed beta helix region NosD PF05048.13 EAX93070.1 - 5.7e-07 29.0 31.6 0.00015 21.1 0.6 4.1 3 1 1 4 4 4 3 Periplasmic copper-binding protein (NosD) DUF3952 PF13130.6 EAX93070.1 - 0.099 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) BTB PF00651.31 EAX93071.1 - 1.5e-13 50.9 1.5 2.9e-13 50.0 0.6 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF3839 PF12943.7 EAX93072.1 - 2.4e-156 518.3 11.1 2.8e-156 518.1 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX93072.1 - 0.013 15.9 0.6 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX93072.1 - 0.15 12.5 5.9 1.5 9.3 0.4 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX93072.1 - 0.34 11.2 3.7 11 6.4 0.1 3.3 3 2 1 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX93072.1 - 0.43 11.1 3.7 0.66 10.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAX93074.1 - 2e-246 796.5 183.3 1.4e-32 111.5 15.4 7.9 2 2 8 10 10 10 9 Phage tail repeat like Apolipoprotein PF01442.18 EAX93074.1 - 0.0014 18.6 3.7 0.2 11.5 1.3 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain HigB_toxin PF09907.9 EAX93074.1 - 0.0055 16.9 5.3 35 4.7 0.0 5.2 1 1 5 6 6 6 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4116 PF13475.6 EAX93074.1 - 0.058 13.1 0.9 0.095 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2785 PF10978.8 EAX93074.1 - 0.07 12.9 14.4 0.99 9.2 4.6 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) AviRa PF11599.8 EAX93074.1 - 0.48 9.8 11.7 0.72 9.3 0.7 3.6 1 1 3 4 4 4 0 RRNA methyltransferase AviRa DUF1493 PF07377.12 EAX93075.1 - 0.022 15.2 0.5 0.048 14.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SHIPPO-rpt PF07004.12 EAX93076.1 - 2.3e-06 28.2 30.3 0.01 16.7 0.0 7.8 6 2 0 6 6 6 3 Sperm-tail PG-rich repeat Macoilin PF09726.9 EAX93076.1 - 4.9 5.6 5.3 6.3 5.2 5.3 1.1 1 0 0 1 1 1 0 Macoilin family Mod_r PF07200.13 EAX93077.1 - 0.00083 19.5 1.4 0.00083 19.5 1.4 5.4 4 1 1 5 5 5 2 Modifier of rudimentary (Mod(r)) protein FtsH_ext PF06480.15 EAX93077.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 FtsH Extracellular DUF349 PF03993.12 EAX93077.1 - 0.5 10.7 0.0 0.5 10.7 0.0 4.3 4 1 0 4 4 4 0 Domain of Unknown Function (DUF349) Laminin_II PF06009.12 EAX93077.1 - 0.74 9.8 35.2 0.21 11.6 1.2 4.3 4 0 0 4 4 4 0 Laminin Domain II DUF2203 PF09969.9 EAX93077.1 - 3.6 8.3 29.5 1.5 9.6 0.5 4.6 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 EAX93077.1 - 5.7 7.0 36.1 0.53 10.3 2.6 5.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EAX93078.1 - 7.4e-05 22.9 10.8 7.4e-05 22.9 10.8 3.7 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding MAD PF05557.13 EAX93078.1 - 0.00015 20.3 10.9 0.00015 20.3 10.9 2.4 1 1 0 2 2 2 1 Mitotic checkpoint protein Cnn_1N PF07989.11 EAX93078.1 - 0.17 12.1 39.5 0.17 12.0 14.0 4.2 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 EAX93078.1 - 0.31 11.5 38.3 0.49 10.8 16.5 2.1 1 1 1 2 2 2 0 Fez1 TSC22 PF01166.18 EAX93078.1 - 1 9.7 34.4 0.1 12.9 2.9 5.2 3 2 2 5 5 5 0 TSC-22/dip/bun family ATG16 PF08614.11 EAX93078.1 - 1.1 9.4 38.7 0.14 12.4 12.5 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EAX93078.1 - 1.8 7.7 40.8 2.8 7.1 13.3 3.6 2 2 0 2 2 2 0 HAP1 N-terminal conserved region GAS PF13851.6 EAX93078.1 - 4.2 6.7 46.3 0.52 9.6 24.8 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_6 PF12774.7 EAX93080.1 - 5.7e-139 462.6 4.6 1.8e-138 461.0 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EAX93080.1 - 7e-106 354.7 17.9 7e-106 354.7 17.9 5.2 6 1 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EAX93080.1 - 1.3e-80 270.9 4.0 2.5e-80 270.0 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EAX93080.1 - 8e-76 254.8 0.1 8e-76 254.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EAX93080.1 - 2.5e-73 245.9 1.3 2.5e-73 245.9 1.3 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EAX93080.1 - 3.4e-49 166.8 0.1 5.4e-46 156.4 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EAX93080.1 - 2e-43 148.0 0.0 5.2e-43 146.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAX93080.1 - 1.5e-33 115.4 0.0 3.6e-32 110.9 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EAX93080.1 - 2.2e-27 96.0 11.4 4.7e-27 94.9 11.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EAX93080.1 - 7.6e-22 77.8 2.0 7.5e-21 74.6 0.1 3.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EAX93080.1 - 3.4e-11 43.3 0.0 0.0015 18.5 0.0 5.7 5 1 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EAX93080.1 - 5e-11 42.7 2.2 3.9e-10 39.8 0.1 3.8 3 1 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 EAX93080.1 - 0.003 18.0 3.7 0.012 16.0 0.0 4.2 5 0 0 5 5 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX93080.1 - 0.0065 16.9 0.0 0.077 13.4 0.0 3.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX93080.1 - 0.019 15.2 0.1 1.4 9.2 0.0 3.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAX93080.1 - 0.17 12.4 1.8 7.8 7.1 0.0 4.6 5 0 0 5 5 2 0 AAA domain Atg14 PF10186.9 EAX93080.1 - 0.21 10.6 18.3 0.43 9.6 11.2 3.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_28 PF13521.6 EAX93080.1 - 0.27 11.5 1.0 11 6.2 0.0 3.5 2 0 0 2 2 2 0 AAA domain Perilipin PF03036.16 EAX93080.1 - 3.8 6.4 17.5 0.63 9.0 5.2 4.2 4 0 0 4 4 4 0 Perilipin family CENP-Q PF13094.6 EAX93080.1 - 10 6.3 22.5 2.9 8.1 12.3 3.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S7 PF00177.21 EAX93081.1 - 2.4e-35 121.4 0.0 3e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Arm_vescicular PF18770.1 EAX93081.1 - 0.051 13.5 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor GPS2_interact PF15784.5 EAX93083.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93083.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX93084.1 - 0.07 13.1 11.1 0.11 12.5 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX93085.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX93086.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX93086.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX93087.1 - 0.053 13.5 0.1 0.082 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX93087.1 - 0.12 12.4 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX93089.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3602 PF12223.8 EAX93090.1 - 0.063 13.9 0.0 0.063 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) MGC-24 PF05283.11 EAX93091.1 - 4.3 7.8 5.5 5.1 7.6 5.5 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FliJ PF02050.16 EAX93093.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Peptidase_M18 PF02127.15 EAX93096.1 - 3.6e-47 161.1 0.0 5.5e-47 160.5 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Dpy-30 PF05186.13 EAX93097.1 - 4.8e-14 51.8 0.1 7.1e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif SNRNP27 PF08648.12 EAX93098.1 - 0.00011 22.2 0.1 0.00044 20.3 0.0 1.9 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins B9-C2 PF07162.11 EAX93099.1 - 4.7e-40 137.6 0.0 5.4e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein TRIC PF05197.13 EAX93101.1 - 4.2e-05 23.2 2.1 6.6e-05 22.6 2.1 1.4 1 0 0 1 1 1 1 TRIC channel PRK PF00485.18 EAX93103.1 - 4e-13 49.6 0.1 3.8e-12 46.3 0.1 2.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RecA PF00154.21 EAX93103.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein MRP-63 PF14978.6 EAX93105.1 - 0.065 13.9 0.3 0.065 13.9 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 GIY-YIG PF01541.24 EAX93106.1 - 0.042 14.1 1.2 0.12 12.6 1.2 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain Ank_4 PF13637.6 EAX93107.1 - 1.2e-68 226.7 25.0 1.2e-12 48.0 0.3 11.7 4 2 9 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX93107.1 - 2.1e-64 211.3 33.8 2.2e-07 31.0 0.2 11.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_2 PF12796.7 EAX93107.1 - 1.4e-62 208.3 38.5 2.7e-19 69.5 6.4 7.8 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93107.1 - 3.3e-47 153.0 23.9 0.00018 21.7 0.0 12.8 12 1 1 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 EAX93107.1 - 1.6e-46 155.8 26.6 1.4e-10 41.2 0.7 7.7 3 3 5 9 9 9 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93107.1 - 1.8e-37 127.1 5.7 1.8e-37 127.1 5.7 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX93107.1 - 3.6e-05 23.9 1.9 2.3 8.5 0.0 6.0 2 1 5 7 7 6 1 N terminal of Calcineurin-like phosphoesterase DUF4093 PF13331.6 EAX93107.1 - 0.0015 19.0 0.4 1.3 9.6 0.0 4.1 2 1 0 3 3 3 1 Domain of unknown function (DUF4093) Ketoacyl-synt_C PF02801.22 EAX93107.1 - 0.0079 16.2 2.9 1.4 9.0 0.2 2.8 2 1 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Ribosomal_S7 PF00177.21 EAX93107.1 - 0.13 11.9 1.4 0.29 10.8 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e Lipoprotein_3 PF00938.17 EAX93107.1 - 0.18 12.0 16.6 16 5.8 0.3 6.8 4 2 2 7 7 7 0 Lipoprotein Abhydro_lipase PF04083.16 EAX93107.1 - 0.33 10.6 8.5 3.3 7.4 0.2 5.5 5 3 0 5 5 5 0 Partial alpha/beta-hydrolase lipase region DUF4147 PF13660.6 EAX93107.1 - 0.5 9.9 4.8 13 5.3 0.2 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4147) Gly-zipper_Omp PF13488.6 EAX93108.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX93108.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX93108.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PapD_N PF00345.20 EAX93110.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX93110.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX93110.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX93111.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX93112.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX93113.1 - 0.043 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3781 PF12636.7 EAX93114.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TLD PF07534.16 EAX93115.1 - 1.5e-21 77.1 0.2 1.8e-21 76.8 0.2 1.0 1 0 0 1 1 1 1 TLD Ank_5 PF13857.6 EAX93117.1 - 5.7e-07 29.7 0.0 8.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93117.1 - 2.9e-06 27.8 0.1 4.4e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93117.1 - 1.4e-05 25.3 0.0 0.00055 20.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EAX93117.1 - 0.00039 20.7 0.0 0.002 18.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX93117.1 - 0.00071 20.1 0.0 0.16 12.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_31 PF13614.6 EAX93118.1 - 0.86 9.5 6.5 0.13 12.1 2.4 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 EAX93118.1 - 2.1 7.6 38.4 1 8.6 24.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 EAX93120.1 - 0.00021 21.0 4.0 0.00021 21.0 4.0 5.1 2 1 1 4 4 3 2 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 EAX93120.1 - 0.0015 18.4 26.2 0.022 14.6 2.2 4.3 3 2 1 4 4 4 3 Apolipoprotein A1/A4/E domain Frankia_peptide PF14407.6 EAX93120.1 - 0.0052 16.7 2.4 3.5 7.7 0.3 3.7 3 0 0 3 3 3 2 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Prefoldin_2 PF01920.20 EAX93120.1 - 0.018 15.0 5.5 0.018 15.0 5.5 6.7 4 2 2 6 6 6 0 Prefoldin subunit DUF885 PF05960.11 EAX93120.1 - 0.058 13.0 10.6 0.15 11.6 3.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) DUF4510 PF14971.6 EAX93120.1 - 0.49 10.7 3.3 3.3 8.0 0.1 3.3 3 1 1 4 4 3 0 Domain of unknown function (DUF4510) DUF883 PF05957.13 EAX93120.1 - 0.73 10.5 9.3 2.6 8.7 1.8 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) MerR-DNA-bind PF09278.11 EAX93120.1 - 1.9 9.1 11.4 13 6.4 2.7 4.0 4 0 0 4 4 4 0 MerR, DNA binding ABC_tran_CTD PF16326.5 EAX93120.1 - 6.1 7.2 29.9 0.56 10.5 0.5 6.1 5 1 0 5 5 5 0 ABC transporter C-terminal domain ParE_toxin PF05016.15 EAX93120.1 - 6.8 7.4 5.2 1.1e+02 3.5 0.1 3.7 3 2 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE CC2-LZ PF16516.5 EAX93120.1 - 7 7.1 30.3 2.5 8.5 5.4 6.6 4 1 2 6 6 6 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ank_2 PF12796.7 EAX93121.1 - 6.5e-25 87.5 0.1 1.4e-12 48.0 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93121.1 - 1.8e-15 56.6 0.2 1.9e-06 28.1 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX93121.1 - 5.6e-13 49.1 3.2 4.6e-08 33.5 0.1 4.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93121.1 - 3e-12 45.6 5.3 2.5e-06 27.4 0.0 6.4 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX93121.1 - 4.8e-12 45.9 0.8 0.00017 21.8 0.0 5.2 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93121.1 - 1.4e-10 41.0 7.3 3.4e-08 33.3 0.2 3.9 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) DUF3587 PF12132.8 EAX93121.1 - 0.04 13.4 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) VSP PF03302.13 EAX93122.1 - 1.8e-05 23.8 2.8 1.8e-05 23.8 2.8 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EAX93122.1 - 0.0029 18.2 0.4 0.0029 18.2 0.4 2.1 3 1 0 3 3 3 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 EAX93122.1 - 0.022 15.2 2.8 0.04 14.4 2.8 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 EAX93122.1 - 2.5 8.2 8.8 4.9 7.2 8.8 1.7 1 1 0 1 1 1 0 Podoplanin ATG16 PF08614.11 EAX93124.1 - 0.0053 17.0 6.2 0.0053 17.0 6.2 3.3 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) HECT PF00632.25 EAX93126.1 - 3.4e-91 305.9 0.9 6.9e-91 304.9 0.9 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EAX93126.1 - 3e-15 56.2 3.3 5.7e-15 55.3 3.3 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Spt20 PF12090.8 EAX93127.1 - 0.00019 21.1 0.2 0.3 10.7 0.1 2.3 1 1 0 2 2 2 2 Spt20 family AAA_assoc PF14363.6 EAX93129.1 - 0.081 13.3 2.6 0.51 10.7 0.2 3.2 2 1 1 3 3 3 0 Domain associated at C-terminal with AAA KIAA1430 PF13879.6 EAX93130.1 - 0.016 16.0 2.5 0.024 15.4 2.5 1.3 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAX93131.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF846 PF05832.12 EAX93133.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Cas_Csa5 PF09702.10 EAX93133.1 - 0.11 12.8 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) AAA_8 PF12780.7 EAX93135.1 - 0.039 13.3 0.1 0.039 13.3 0.1 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 ACT_4 PF13291.6 EAX93136.1 - 0.4 11.3 3.8 1 10.0 0.2 3.1 3 0 0 3 3 3 0 ACT domain HECT PF00632.25 EAX93137.1 - 7.2e-17 61.8 0.1 3.3e-16 59.7 0.0 2.1 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3447 PF11929.8 EAX93138.1 - 7.4e-37 125.2 5.9 7.4e-37 125.2 5.9 5.0 3 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93138.1 - 6.4e-30 103.6 7.4 5.7e-15 55.7 0.3 4.9 3 3 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93138.1 - 4.8e-21 74.8 8.7 3.6e-09 37.0 0.1 6.7 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93138.1 - 1.5e-19 68.0 9.0 0.00036 20.7 0.0 7.8 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EAX93138.1 - 2e-19 69.1 5.8 6.8e-06 26.3 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX93138.1 - 6.9e-15 54.9 6.0 5.2e-05 23.4 0.4 5.1 2 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF4988 PF16378.5 EAX93138.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Ank_4 PF13637.6 EAX93139.1 - 4.7e-27 94.0 0.2 1.1e-09 38.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93139.1 - 5.7e-26 90.3 0.5 1.6e-12 47.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93139.1 - 1.1e-22 79.4 0.0 2.5e-09 37.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX93139.1 - 1.6e-21 76.7 0.3 2.3e-19 69.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93139.1 - 1.8e-20 70.9 0.1 1.4e-07 31.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Fer4_14 PF13394.6 EAX93139.1 - 0.042 14.0 0.1 2.1 8.5 0.1 2.0 1 1 1 2 2 2 0 4Fe-4S single cluster domain MitMem_reg PF13012.6 EAX93140.1 - 0.19 12.1 1.8 0.62 10.5 0.4 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Erf4 PF10256.9 EAX93140.1 - 3.5 7.8 7.7 17 5.5 0.1 3.8 3 1 1 4 4 4 0 Golgin subfamily A member 7/ERF4 family ABC_tran_CTD PF16326.5 EAX93140.1 - 4.3 7.7 6.5 1.2 9.4 0.7 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain T_Ag_DNA_bind PF02217.16 EAX93140.1 - 7.9 7.2 7.6 28 5.4 0.2 3.2 3 0 0 3 3 3 0 Origin of replication binding protein JUPITER PF17054.5 EAX93141.1 - 0.34 10.3 1.8 0.55 9.6 1.8 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Colicin_immun PF09204.10 EAX93141.1 - 0.36 11.4 6.2 0.16 12.5 1.8 2.7 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity IFN-gamma PF00714.17 EAX93142.1 - 0.0068 16.2 1.5 0.01 15.7 1.5 1.2 1 0 0 1 1 1 1 Interferon gamma YtxH PF12732.7 EAX93142.1 - 0.015 15.8 0.2 0.028 14.9 0.2 1.4 1 0 0 1 1 1 0 YtxH-like protein Syntaxin_2 PF14523.6 EAX93142.1 - 0.034 14.5 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Syntaxin-like protein CM_2 PF01817.21 EAX93142.1 - 0.078 13.3 0.2 0.18 12.2 0.2 1.6 1 0 0 1 1 1 0 Chorismate mutase type II Ribosomal_L27e PF01777.18 EAX93143.1 - 2.2e-21 76.0 6.8 2.8e-21 75.6 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAX93143.1 - 0.0062 16.4 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAX93143.1 - 0.16 11.4 0.1 0.18 11.2 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SNF2_N PF00176.23 EAX93144.1 - 2.7e-53 180.9 0.1 4.3e-53 180.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX93144.1 - 4.3e-21 75.3 0.0 1.5e-20 73.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FYRN PF05964.14 EAX93144.1 - 9.7e-17 60.6 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EAX93144.1 - 1.7e-16 60.1 0.0 5.5e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 EAX93144.1 - 1.1e-15 57.2 0.8 3.9e-08 33.1 0.1 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EAX93144.1 - 5.8e-10 39.4 0.0 5.8e-10 39.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EAX93144.1 - 6.3e-07 29.4 2.7 0.00029 20.9 0.0 4.0 3 1 1 4 4 3 1 SLIDE HDA2-3 PF11496.8 EAX93144.1 - 0.00014 21.1 4.7 0.0014 17.9 1.2 3.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 EAX93144.1 - 0.0013 18.8 0.2 4.3 7.6 0.1 3.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 EAX93144.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_14 PF13173.6 EAX93144.1 - 0.098 12.7 0.2 1 9.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain Myb_DNA-bind_6 PF13921.6 EAX93144.1 - 0.8 10.0 4.7 1.3 9.3 0.1 3.5 4 0 0 4 4 3 0 Myb-like DNA-binding domain TMEM51 PF15345.6 EAX93144.1 - 1.8 8.4 5.9 3.8 7.3 5.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 NOA36 PF06524.12 EAX93144.1 - 6 6.1 10.1 14 4.9 10.1 1.5 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 EAX93144.1 - 9.8 4.8 8.4 17 4.0 8.4 1.3 1 0 0 1 1 1 0 Presenilin Ank_5 PF13857.6 EAX93146.1 - 3e-19 68.8 1.2 2.5e-07 30.8 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93146.1 - 8.3e-18 64.8 5.9 1.4e-09 38.4 0.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93146.1 - 4.3e-17 62.3 1.2 2.6e-07 31.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93146.1 - 1.9e-16 59.7 0.2 2.4e-07 30.9 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX93146.1 - 1e-15 56.2 0.4 3.8e-06 26.8 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat DUF4258 PF14076.6 EAX93146.1 - 0.0035 17.7 0.2 0.071 13.5 0.2 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4258) DJ-1_PfpI PF01965.24 EAX93148.1 - 7.9e-38 129.9 0.1 9.4e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DHHC PF01529.20 EAX93149.1 - 3.8e-31 107.9 6.5 3.8e-31 107.9 6.5 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF3937 PF13073.6 EAX93149.1 - 0.014 15.5 0.3 0.014 15.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3937) DPM3 PF08285.11 EAX93149.1 - 9.6 6.5 9.5 1.3 9.3 1.4 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MMACHC PF16690.5 EAX93150.1 - 0.082 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Phage_Gp23 PF10669.9 EAX93150.1 - 2.2 8.6 6.2 3.6 7.9 1.4 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Guanylate_cyc PF00211.20 EAX93151.1 - 4.2e-38 130.8 0.5 7.4e-38 130.0 0.5 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Lectin_N PF03954.14 EAX93151.1 - 0.024 14.4 3.3 0.16 11.7 0.1 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain PAS_9 PF13426.7 EAX93151.1 - 0.034 14.4 1.0 0.09 13.0 0.3 2.1 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 EAX93151.1 - 0.12 12.4 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 PAS domain GAPT PF11770.8 EAX93151.1 - 0.2 11.5 3.7 5.9 6.7 0.1 2.6 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) MAP17 PF15807.5 EAX93151.1 - 0.26 11.5 0.1 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF5367 PF17329.2 EAX93151.1 - 1.5 9.0 10.2 4.2 7.6 0.6 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5367) Ly49 PF08391.10 EAX93151.1 - 3.1 8.2 7.5 0.23 11.9 0.3 2.6 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Spo0A_C PF08769.11 EAX93152.1 - 0.056 13.5 0.3 0.13 12.4 0.2 1.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal FliJ PF02050.16 EAX93153.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX93154.1 - 1.1e-71 240.2 4.0 1.5e-71 239.8 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TMEM131_like PF12371.8 EAX93157.1 - 0.00045 20.4 0.8 0.00045 20.4 0.8 5.7 6 1 0 6 6 6 1 Transmembrane protein 131-like DUF1573 PF07610.11 EAX93157.1 - 0.00099 19.1 7.4 1 9.4 0.2 4.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1573) DUF4283 PF14111.6 EAX93157.1 - 0.041 13.4 0.9 0.16 11.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4283) Prismane PF03063.20 EAX93159.1 - 0.031 13.0 0.1 0.041 12.6 0.1 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF2833 PF11090.8 EAX93159.1 - 0.059 13.8 0.6 0.16 12.4 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2833) STAT_int PF02865.17 EAX93160.1 - 0.2 12.1 1.9 0.3 11.5 0.5 2.0 2 1 0 2 2 2 0 STAT protein, protein interaction domain HSP70 PF00012.20 EAX93162.1 - 4.9e-21 74.6 0.0 5.3e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 EAX93163.1 - 9.4e-10 37.3 0.4 1.2e-09 37.0 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein STOP PF05217.12 EAX93165.1 - 0.11 12.9 8.7 3 8.2 0.0 3.8 4 0 0 4 4 4 0 STOP protein DUF3839 PF12943.7 EAX93166.1 - 1.2e-153 509.5 12.3 1.5e-153 509.1 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX93166.1 - 0.65 10.5 4.9 1.8 9.0 0.5 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX93166.1 - 0.86 10.2 4.2 2.2 8.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAX93166.1 - 1.8 8.9 4.0 1.4 9.2 1.1 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF5106 PF17127.4 EAX93167.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) DUF1043 PF06295.12 EAX93168.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAX93168.1 - 0.14 12.2 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX93169.1 - 0.021 15.2 0.5 0.025 15.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX93169.1 - 2 8.4 4.5 2.1 8.3 4.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX93170.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX93171.1 - 0.15 12.0 10.6 0.23 11.4 10.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX93171.1 - 1.8 9.0 5.4 2.5 8.5 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX93172.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93172.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX93173.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Peripla_BP_2 PF01497.18 EAX93174.1 - 0.0027 17.3 0.0 0.0084 15.7 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein GPS2_interact PF15784.5 EAX93175.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93175.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 EAX93176.1 - 4.9e-13 48.1 0.0 9.3e-06 24.1 0.0 2.6 2 1 0 3 3 3 2 Hsp70 protein MOZ_SAS PF01853.18 EAX93177.1 - 5.4e-70 234.7 0.1 8.6e-70 234.0 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAX93177.1 - 7.2e-22 76.7 0.5 1.8e-21 75.5 0.5 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAX93177.1 - 1.2e-07 31.5 0.1 2.8e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 EAX93177.1 - 0.0014 18.8 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C2H2 PF00096.26 EAX93177.1 - 0.0042 17.5 0.4 0.0081 16.6 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAX93177.1 - 0.009 16.8 0.3 0.03 15.2 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger PWWP PF00855.17 EAX93177.1 - 0.064 13.7 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 PWWP domain DUF600 PF04634.12 EAX93177.1 - 1.4 8.9 9.0 0.26 11.3 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF600 BOP1NT PF08145.12 EAX93178.1 - 1.7e-47 162.6 14.6 3.2e-35 122.3 6.7 2.2 1 1 1 2 2 2 2 BOP1NT (NUC169) domain WD40 PF00400.32 EAX93178.1 - 1.3e-21 76.5 7.9 1.8e-07 31.8 0.2 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93178.1 - 6.1e-06 26.4 0.0 0.31 11.4 0.0 4.4 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX93178.1 - 0.0054 15.7 0.0 0.019 13.9 0.0 1.9 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAX93178.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DHHC PF01529.20 EAX93179.1 - 2.8e-26 92.2 14.2 2.8e-26 92.2 14.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2284 PF10050.9 EAX93179.1 - 0.0099 15.6 1.9 0.019 14.7 1.9 1.5 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) Ank_2 PF12796.7 EAX93180.1 - 4.2e-26 91.3 6.1 4.7e-13 49.5 0.1 3.9 1 1 4 5 5 5 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX93180.1 - 1.7e-16 59.9 4.3 1.7e-16 59.9 4.3 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93180.1 - 8e-14 51.8 3.4 3.9e-06 27.3 0.0 5.4 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93180.1 - 2.4e-13 49.9 0.6 4e-06 27.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX93180.1 - 6.5e-08 32.7 0.2 4.3e-05 23.7 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93180.1 - 4.3e-07 29.7 10.4 0.0041 17.5 0.0 6.8 8 0 0 8 8 8 2 Ankyrin repeat Endonuc-PvuII PF09225.10 EAX93180.1 - 0.0082 15.9 0.1 5.2 6.8 0.0 2.5 2 0 0 2 2 2 2 Restriction endonuclease PvuII PQQ_3 PF13570.6 EAX93181.1 - 0.00013 22.3 0.6 0.037 14.5 0.4 3.0 2 1 0 2 2 2 2 PQQ-like domain Pre-PUA PF17832.1 EAX93181.1 - 0.18 12.5 0.3 0.54 11.0 0.3 1.8 1 0 0 1 1 1 0 Pre-PUA-like domain PSP PF04046.16 EAX93182.1 - 0.39 10.6 4.1 0.24 11.3 0.6 2.5 2 1 0 2 2 2 0 PSP TMP PF05017.14 EAX93183.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93184.1 - 0.019 15.4 0.7 0.04 14.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX93185.1 - 3.6e-34 116.6 23.9 4e-31 106.9 15.9 4.4 5 1 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX93185.1 - 0.091 12.5 0.6 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX93187.1 - 9e-155 513.2 13.3 1.1e-154 512.9 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX93187.1 - 0.079 13.4 2.5 0.12 12.8 0.5 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX93187.1 - 0.18 11.7 2.4 0.27 11.1 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX93187.1 - 1.1 9.8 5.9 6.1 7.4 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX93187.1 - 1.7 9.0 5.6 12 6.3 0.1 3.6 4 1 0 4 4 4 0 Tup N-terminal KilA-N PF04383.13 EAX93188.1 - 2.2e-34 117.7 0.1 3e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAX93188.1 - 0.095 12.7 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon KilA-N PF04383.13 EAX93189.1 - 5.8e-35 119.5 0.9 9.7e-35 118.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Pax7 PF12360.8 EAX93190.1 - 0.2 11.8 0.3 15 5.9 0.0 2.1 1 1 1 2 2 2 0 Paired box protein 7 Pox_A32 PF04665.12 EAX93191.1 - 6.8e-07 29.0 2.5 6.8e-07 29.0 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93191.1 - 3.4e-05 24.1 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93191.1 - 4.7e-05 23.2 0.3 0.32 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93191.1 - 0.00014 21.9 3.0 0.00029 20.9 3.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93191.1 - 0.00064 19.5 0.1 0.0013 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93191.1 - 0.0012 18.7 0.5 0.0024 17.7 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93191.1 - 0.004 16.8 0.4 0.03 14.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93191.1 - 0.009 16.4 0.0 0.028 14.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX93191.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93191.1 - 0.086 13.3 0.1 0.71 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93191.1 - 0.097 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93191.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAX93191.1 - 7.4 6.8 14.0 2.9 8.1 0.1 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF2666) DUF563 PF04577.14 EAX93194.1 - 9.3e-24 84.7 0.4 1.2e-23 84.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) zf-CCCH_4 PF18044.1 EAX93195.1 - 4.2e-06 26.4 2.4 7e-06 25.7 2.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAX93195.1 - 3.9e-05 23.5 6.0 7.7e-05 22.6 6.0 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EAX93195.1 - 0.014 15.3 0.4 0.031 14.2 0.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sirohm_synth_C PF14823.6 EAX93195.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Methyltransf_25 PF13649.6 EAX93196.1 - 1.2e-11 45.2 0.0 2.9e-11 43.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EAX93196.1 - 2.4e-10 40.3 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EAX93196.1 - 1.1e-09 38.2 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX93196.1 - 2e-08 34.7 0.0 4.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EAX93196.1 - 2.7e-06 27.4 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 EAX93196.1 - 2.4e-05 24.0 0.1 4.3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EAX93196.1 - 2.8e-05 24.0 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAX93196.1 - 3.4e-05 23.3 0.1 6.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EAX93196.1 - 0.00012 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAX93196.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EAX93196.1 - 0.00034 21.3 0.0 0.00063 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAX93196.1 - 0.00044 19.3 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EAX93196.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 EAX93196.1 - 0.063 13.4 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EAX93196.1 - 0.09 13.8 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EAX93196.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 EAX93196.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EAX93196.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Myb_DNA-binding PF00249.31 EAX93197.1 - 1e-25 89.7 0.1 1.7e-13 50.5 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93197.1 - 2.2e-23 82.3 1.3 9.4e-15 54.6 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX93197.1 - 4.9e-07 29.8 0.1 0.021 14.8 0.0 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX93197.1 - 0.00061 19.6 0.5 0.3 11.0 0.1 2.4 2 1 0 2 2 2 2 Myb DNA-binding like DUF4177 PF13783.6 EAX93197.1 - 0.012 15.8 0.0 0.034 14.4 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4177) DUF1100 PF06500.11 EAX93197.1 - 0.089 11.6 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PH_4 PF15404.6 EAX93197.1 - 0.1 12.4 0.3 0.18 11.6 0.1 1.5 2 0 0 2 2 2 0 Pleckstrin homology domain LRR_5 PF13306.6 EAX93198.1 - 5.5e-71 236.5 25.4 1e-25 90.2 1.3 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93198.1 - 1.6e-19 69.4 0.1 0.00011 21.9 0.0 7.1 3 2 5 8 8 8 7 Leucine rich repeat WD40 PF00400.32 EAX93199.1 - 2.4e-20 72.5 9.9 0.00097 19.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93199.1 - 6.9e-14 51.9 0.1 0.0018 18.5 0.0 6.2 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX93199.1 - 0.00039 19.8 1.8 0.0013 18.1 1.4 2.0 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EAX93199.1 - 0.0016 17.5 1.4 0.077 11.9 0.5 3.8 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EAX93199.1 - 0.018 14.7 0.0 0.52 10.0 0.0 2.6 2 1 0 2 2 2 0 TUP1-like enhancer of split Thioredoxin PF00085.20 EAX93201.1 - 5.7e-19 68.0 0.2 2.6e-18 65.9 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 EAX93201.1 - 3e-07 30.5 4.4 4.2e-06 26.8 2.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAX93201.1 - 5.5e-06 26.8 0.1 2e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EAX93201.1 - 0.0002 21.2 1.5 0.0044 16.8 0.1 2.6 3 0 0 3 3 3 1 Thioredoxin OST3_OST6 PF04756.13 EAX93201.1 - 0.00032 20.2 0.4 0.00032 20.2 0.4 2.1 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EAX93201.1 - 0.00049 20.4 0.8 0.01 16.1 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAX93201.1 - 0.0043 17.2 0.2 0.014 15.5 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 EAX93201.1 - 0.011 15.9 2.9 0.042 14.0 0.2 2.6 1 1 2 3 3 3 0 Thioredoxin AhpC-TSA PF00578.21 EAX93201.1 - 0.017 15.0 0.1 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EAX93201.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Glutaredoxin DUF836 PF05768.14 EAX93201.1 - 0.094 13.1 0.2 0.47 10.9 0.1 2.3 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) SHIPPO-rpt PF07004.12 EAX93202.1 - 3.7e-39 131.9 142.4 0.00011 22.9 1.9 19.8 21 0 0 21 21 21 13 Sperm-tail PG-rich repeat DUF1502 PF07397.11 EAX93202.1 - 0.075 12.9 7.3 62 3.6 0.2 5.2 4 0 0 4 4 4 0 Repeat of unknown function (DUF1502) Herpes_UL37_1 PF03970.13 EAX93204.1 - 0.24 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein HAD_2 PF13419.6 EAX93205.1 - 1.3e-07 31.9 0.3 2.3e-07 31.1 0.3 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 EAX93205.1 - 0.00059 19.6 0.8 0.0022 17.8 0.8 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4107 PF13389.6 EAX93206.1 - 6.8e-73 244.2 3.8 8.7e-73 243.8 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX93207.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX93209.1 - 6.7e-104 346.6 7.1 7.7e-104 346.4 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TMP PF05017.14 EAX93212.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX93212.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MULE PF10551.9 EAX93213.1 - 3.9e-13 49.6 0.1 8.3e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX93213.1 - 0.22 11.2 4.6 0.3 10.7 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX93213.1 - 0.63 10.3 5.6 1.8 8.9 5.6 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX93213.1 - 1.5 8.6 5.3 2.6 7.8 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Chlam_PMP PF02415.17 EAX93214.1 - 0.0016 18.8 39.3 0.0059 17.0 0.6 6.8 8 0 0 8 8 8 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Orf78 PF06024.12 EAX93214.1 - 0.0045 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 EAX93214.1 - 0.0058 16.5 0.7 0.013 15.4 0.3 1.7 2 0 0 2 2 2 1 TMEM154 protein family TMEM51 PF15345.6 EAX93214.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_M56 PF05569.11 EAX93214.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 CwsA PF10814.8 EAX93214.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA 7tm_2 PF00002.24 EAX93214.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Aldo_ket_red PF00248.21 EAX93215.1 - 7.2e-47 160.0 0.1 1.4e-46 159.0 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family ABC2_membrane_3 PF12698.7 EAX93216.1 - 5.7e-31 107.9 26.6 7.9e-31 107.4 26.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EAX93216.1 - 5.3e-28 98.2 0.0 8.3e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX93216.1 - 1.5e-13 51.3 0.3 2.2e-07 31.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX93216.1 - 2.2e-06 27.3 4.0 0.01 15.3 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAX93216.1 - 5.9e-05 23.0 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EAX93216.1 - 0.00033 21.2 0.2 0.00072 20.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAX93216.1 - 0.0053 16.5 4.3 0.073 12.8 1.7 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EAX93216.1 - 0.0062 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EAX93216.1 - 0.062 12.7 0.1 0.77 9.1 0.0 2.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EAX93216.1 - 0.15 12.1 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 EAX93216.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX93218.1 - 2.4e-26 92.9 0.0 4.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX93218.1 - 8.7e-09 34.9 27.7 1.4e-08 34.3 27.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAX93218.1 - 2.2e-08 34.3 5.1 4e-06 26.9 0.1 2.7 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAX93218.1 - 0.0091 16.5 0.8 0.021 15.3 0.8 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAX93218.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EAX93218.1 - 0.12 11.8 5.0 0.26 10.7 0.1 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAX93218.1 - 0.15 11.9 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAX93218.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4690 PF15756.5 EAX93219.1 - 0.0036 17.8 0.0 0.0081 16.7 0.0 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EAX93219.1 - 0.0047 17.0 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 Podoplanin Epiglycanin_C PF14654.6 EAX93220.1 - 0.021 14.9 0.1 0.055 13.5 0.1 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region TMEM107 PF14995.6 EAX93220.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein Claudin_2 PF13903.6 EAX93220.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Podoplanin PF05808.11 EAX93220.1 - 0.28 11.3 0.1 0.28 11.3 0.1 1.8 2 1 0 2 2 2 0 Podoplanin TFCD_C PF12612.8 EAX93221.1 - 0.0038 17.1 6.8 0.048 13.5 0.4 4.8 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal DUF5475 PF17569.2 EAX93221.1 - 0.77 10.1 4.7 4.2 7.7 0.0 4.1 4 1 0 4 4 4 0 Family of unknown function (DUF5475) Ank_2 PF12796.7 EAX93222.1 - 5.4e-17 62.1 4.8 2.1e-08 34.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93222.1 - 3.8e-16 59.2 1.4 2.2e-06 28.1 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93222.1 - 1.1e-12 48.0 0.1 7.2e-07 29.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93222.1 - 1.7e-10 40.2 1.4 0.00053 20.2 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX93222.1 - 1.1e-05 25.7 0.2 0.033 14.6 0.1 4.1 4 1 0 4 4 4 1 Ankyrin repeat YjcQ PF09639.10 EAX93222.1 - 0.019 15.1 0.2 0.29 11.3 0.1 2.5 2 0 0 2 2 2 0 YjcQ protein CCDC74_C PF14917.6 EAX93222.1 - 0.44 11.1 3.3 1.2 9.7 0.5 2.5 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal APG6_N PF17675.1 EAX93222.1 - 0.66 10.5 5.7 1.3 9.6 3.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Med21 PF11221.8 EAX93222.1 - 0.93 9.7 6.0 0.24 11.6 0.6 2.3 1 1 0 2 2 2 0 Subunit 21 of Mediator complex DUF2407_C PF13373.6 EAX93222.1 - 1.2 9.4 4.2 14 5.9 0.5 2.3 1 1 1 2 2 2 0 DUF2407 C-terminal domain Med9 PF07544.13 EAX93222.1 - 2.1 8.5 7.1 1.8 8.7 0.1 3.2 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TTL PF03133.15 EAX93223.1 - 6.4e-51 173.2 0.0 8.9e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX93223.1 - 1.8e-11 43.8 0.0 7.4e-05 22.1 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX93223.1 - 5.6e-08 32.4 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX93223.1 - 0.00045 20.3 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain TonB_2 PF13103.6 EAX93224.1 - 0.0065 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 TonB C terminal TIG PF01833.24 EAX93224.1 - 0.088 12.9 2.5 0.1 12.7 0.0 2.4 3 0 0 3 3 3 0 IPT/TIG domain TIG_plexin PF17960.1 EAX93224.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.4 4 0 0 4 4 4 0 TIG domain EGF_3 PF12947.7 EAX93224.1 - 0.34 11.1 17.2 0.15 12.3 10.9 2.6 2 1 0 2 2 2 0 EGF domain Metallothio PF00131.20 EAX93224.1 - 2 8.6 14.5 3.5 7.8 14.5 1.4 1 0 0 1 1 1 0 Metallothionein Pkinase PF00069.25 EAX93225.1 - 5e-71 239.1 0.0 6.5e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93225.1 - 1.7e-37 129.1 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93225.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 EAX93225.1 - 3.4e-05 24.3 0.2 9.2e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 PH domain YrbL-PhoP_reg PF10707.9 EAX93225.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PH_11 PF15413.6 EAX93225.1 - 0.079 13.4 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 EAX93225.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PSP PF04046.16 EAX93226.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93227.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93228.1 - 0.053 14.0 0.6 0.11 12.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX93229.1 - 1.8e-64 213.7 43.4 3.6e-34 116.6 15.4 7.5 6 2 3 9 9 9 3 Phage tail repeat like DUF3391 PF11871.8 EAX93229.1 - 0.071 13.6 3.3 0.99 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX93229.1 - 0.095 12.4 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX93229.1 - 4.2 6.9 28.7 0.094 12.3 5.5 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX93231.1 - 1.6e-149 496.0 9.2 2e-149 495.7 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX93231.1 - 0.017 15.6 0.5 0.099 13.1 0.0 2.0 2 0 0 2 2 2 0 Fez1 Rx_N PF18052.1 EAX93231.1 - 0.047 14.0 1.5 2 8.7 0.0 3.5 3 1 1 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX93231.1 - 0.16 12.5 3.9 1.9 9.0 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APC_N_CC PF16689.5 EAX93233.1 - 0.14 12.3 0.4 0.14 12.3 0.4 3.1 4 1 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain gpW PF02831.15 EAX93233.1 - 0.16 11.9 0.1 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 gpW DHR-2 PF06920.13 EAX93234.1 - 2.3e-20 72.8 2.7 2.3e-20 72.8 2.7 3.2 2 1 0 3 3 3 1 Dock homology region 2 SH3_1 PF00018.28 EAX93234.1 - 0.00085 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3385 PF11865.8 EAX93235.1 - 0.67 9.8 4.8 1.4 8.8 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Neuropep_like PF15161.6 EAX93236.1 - 0.086 12.5 0.9 18 5.1 0.1 2.7 2 0 0 2 2 2 0 Neuropeptide-like MoCF_biosynth PF00994.24 EAX93236.1 - 0.85 9.3 2.9 2.5 7.8 0.1 2.7 3 0 0 3 3 3 0 Probable molybdopterin binding domain V_ATPase_I PF01496.19 EAX93236.1 - 2.4 6.0 29.2 0.003 15.6 10.8 2.7 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family ApoO PF09769.9 EAX93236.1 - 8.2 6.4 8.1 6.6 6.7 0.1 4.0 2 2 2 4 4 4 0 Apolipoprotein O ArAE_1_C PF11728.8 EAX93237.1 - 0.046 13.7 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Metallophos PF00149.28 EAX93238.1 - 6.7e-39 134.5 0.3 8.3e-39 134.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX93238.1 - 0.0094 16.4 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX93238.1 - 0.035 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GDI PF00996.18 EAX93240.1 - 3.5e-37 128.0 0.0 4.7e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor JHY PF15261.6 EAX93241.1 - 1.3e-05 25.9 9.8 1.3e-05 25.9 9.8 1.9 2 0 0 2 2 2 1 Jhy protein NINJA_B PF16136.5 EAX93241.1 - 0.095 13.1 2.2 0.15 12.5 2.2 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal RabGAP-TBC PF00566.18 EAX93242.1 - 6.3e-14 52.1 8.6 1.5e-13 50.9 8.6 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4457 PF14652.6 EAX93243.1 - 0.0002 20.7 1.9 0.023 13.9 0.1 2.9 1 1 0 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 EAX93243.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal PRKG1_interact PF15898.5 EAX93245.1 - 0.002 19.0 28.7 0.12 13.3 6.7 3.2 3 0 0 3 3 3 2 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 EAX93245.1 - 0.0074 16.8 21.3 0.18 12.3 19.4 3.0 1 1 1 2 2 2 1 Fez1 HrpB7 PF09486.10 EAX93245.1 - 0.035 14.5 1.6 0.15 12.4 0.4 2.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF3037 PF11236.8 EAX93245.1 - 0.042 14.3 2.5 1.8 9.0 0.6 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3037) Tropomyosin PF00261.20 EAX93245.1 - 0.047 13.1 17.4 0.016 14.6 6.4 2.7 1 1 1 2 2 2 0 Tropomyosin DUF4407 PF14362.6 EAX93245.1 - 0.1 12.0 15.8 0.24 10.7 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 EAX93245.1 - 0.27 10.7 27.1 0.74 9.3 19.1 2.8 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Sod_Ni PF09055.11 EAX93245.1 - 0.97 10.0 4.9 0.54 10.8 1.6 2.2 1 1 0 2 2 2 0 Nickel-containing superoxide dismutase MbeD_MobD PF04899.12 EAX93245.1 - 1.3 9.2 5.4 25 5.1 0.1 2.9 2 0 0 2 2 2 0 MbeD/MobD like DUF4349 PF14257.6 EAX93245.1 - 3.4 7.1 5.9 0.6 9.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) IBD PF10416.9 EAX93246.1 - 8.3e-43 145.5 1.3 1.1e-42 145.0 1.3 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Ubiquitin_3 PF14836.6 EAX93246.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Rcd1 PF04078.13 EAX93247.1 - 5.3e-62 209.4 7.1 6.9e-62 209.1 7.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TF_Otx PF03529.13 EAX93247.1 - 0.057 13.8 0.3 0.093 13.1 0.3 1.4 1 0 0 1 1 1 0 Otx1 transcription factor ubiquitin PF00240.23 EAX93248.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EAX93248.1 - 0.0042 17.6 0.0 0.0075 16.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain F5_F8_type_C PF00754.25 EAX93249.1 - 6.5e-07 29.5 0.3 2.3e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain Gly_rich PF12810.7 EAX93250.1 - 3.2e-21 76.3 21.0 3.8e-21 76.1 21.0 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX93251.1 - 1e-112 371.4 84.0 5.5e-29 100.7 5.2 7.3 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93251.1 - 1.4e-20 72.8 6.8 0.0032 17.2 0.2 8.5 7 2 1 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EAX93251.1 - 0.083 13.3 19.0 1.3 9.6 0.9 7.4 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) F5_F8_type_C PF00754.25 EAX93252.1 - 2.1e-06 27.9 0.0 7.4e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain Gly_rich PF12810.7 EAX93253.1 - 6.4e-11 42.6 41.3 1.3e-10 41.6 41.3 1.5 1 1 0 1 1 1 1 Glycine rich protein Tubulin PF00091.25 EAX93254.1 - 1.2e-69 234.5 0.0 1.8e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX93254.1 - 1.1e-33 116.1 0.0 2.4e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAX93254.1 - 2.9e-06 27.6 0.0 6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAX93254.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 EAX93254.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DnaA_N PF11638.8 EAX93254.1 - 0.13 12.1 1.4 6 6.7 0.0 3.3 4 0 0 4 4 4 0 DnaA N-terminal domain Gly_rich PF12810.7 EAX93256.1 - 1.4e-23 84.0 22.1 1.7e-23 83.8 22.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93257.1 - 1.9e-09 37.8 0.1 2.3e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX93258.1 - 2.5e-17 63.0 4.9 7.7e-17 61.5 4.9 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93258.1 - 4.6e-07 29.5 0.0 0.0022 17.7 0.0 2.0 1 1 1 2 2 2 2 Leucine rich repeat Gly_rich PF12810.7 EAX93259.1 - 1.2e-26 94.1 27.3 1.4e-26 93.9 27.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93260.1 - 6e-17 62.4 82.6 5.5e-15 55.9 82.6 2.5 1 1 0 1 1 1 1 Glycine rich protein MatE PF01554.18 EAX93261.1 - 1.7e-15 57.1 6.9 1.7e-15 57.1 6.9 1.8 2 0 0 2 2 2 1 MatE DUF1761 PF08570.10 EAX93261.1 - 0.049 13.9 3.3 0.078 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) ECF_trnsprt PF12822.7 EAX93261.1 - 0.23 11.6 14.1 0.057 13.5 9.5 2.2 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF2929 PF11151.8 EAX93261.1 - 6.3 7.2 9.5 1.1 9.6 1.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) TMP PF05017.14 EAX93262.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93263.1 - 0.079 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX93264.1 - 3.4e-24 84.6 28.2 6.5e-22 77.4 7.7 5.4 3 2 3 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX93264.1 - 0.065 13.0 0.1 0.27 11.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) SAS4 PF15460.6 EAX93264.1 - 0.099 12.7 6.1 3.4 7.8 1.8 2.9 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF3839 PF12943.7 EAX93265.1 - 2.8e-157 521.4 12.1 3.4e-157 521.1 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX93265.1 - 0.085 13.3 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX93265.1 - 1.9 9.0 7.9 2.2 8.8 0.9 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX93266.1 - 9e-05 23.0 0.1 0.00021 21.8 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX93266.1 - 0.16 11.5 0.3 1 8.8 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain Flavodoxin_2 PF02525.17 EAX93267.1 - 4.2e-27 95.2 0.0 1.1e-26 93.8 0.0 1.5 1 1 1 2 2 2 1 Flavodoxin-like fold FMN_red PF03358.15 EAX93267.1 - 0.1 12.4 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Trypan_PARP PF05887.11 EAX93269.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4263 PF14082.6 EAX93271.1 - 0.045 14.0 0.3 0.075 13.3 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) Flavodoxin_2 PF02525.17 EAX93274.1 - 2.6e-36 125.2 0.0 3.5e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX93274.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.1 1 1 0 1 1 1 0 NADPH-dependent FMN reductase KilA-N PF04383.13 EAX93276.1 - 6.9e-23 80.6 0.3 1.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX93276.1 - 0.047 13.7 0.7 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX93276.1 - 0.22 10.9 0.5 1.1 8.7 0.2 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Amidase02_C PF12123.8 EAX93277.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX93278.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Metallophos PF00149.28 EAX93280.1 - 1.2e-30 107.6 0.5 1.5e-30 107.3 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DENN PF02141.21 EAX93281.1 - 8.8e-19 68.2 0.5 2.2e-18 66.9 0.5 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EAX93281.1 - 4.5e-07 30.5 1.5 1.3e-06 29.1 1.5 1.8 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 EAX93281.1 - 0.0024 17.8 1.1 0.0066 16.4 0.1 2.2 2 1 0 2 2 2 1 Stabilization of polarity axis KRBA1 PF15287.6 EAX93282.1 - 0.0062 16.2 0.3 0.0062 16.2 0.3 2.7 2 0 0 2 2 2 1 KRBA1 family repeat Arm PF00514.23 EAX93284.1 - 0.0041 17.1 3.1 2.1 8.5 0.0 4.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat zf-RING_2 PF13639.6 EAX93285.1 - 0.00011 22.4 17.5 0.00026 21.3 17.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX93285.1 - 0.00012 21.8 17.9 0.00012 21.8 17.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX93285.1 - 0.00032 20.5 17.9 0.00061 19.6 17.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAX93285.1 - 0.00073 19.3 14.1 0.00073 19.3 14.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX93285.1 - 0.00088 19.3 13.1 0.00088 19.3 13.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX93285.1 - 0.0013 18.7 19.5 0.0022 17.9 18.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAX93285.1 - 0.39 10.8 9.2 0.72 9.9 9.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EAX93285.1 - 0.85 9.5 14.6 2 8.3 14.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EAX93285.1 - 0.9 9.8 17.8 2.2 8.5 17.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAX93285.1 - 2 8.4 17.9 4.2 7.3 17.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 EAX93286.1 - 4.5e-37 127.9 0.0 5.8e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93286.1 - 4.7e-28 98.2 0.0 5.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93286.1 - 2.9e-07 30.1 0.0 4.9e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PSP PF04046.16 EAX93287.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93288.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX93290.1 - 3.3e-157 521.2 14.0 4.1e-157 520.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX93290.1 - 0.094 13.0 0.3 1.7 9.0 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX93290.1 - 0.18 11.6 1.4 0.64 9.9 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX93290.1 - 0.59 10.6 6.9 2.3 8.8 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX93292.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX93293.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TFIIA_gamma_N PF02268.16 EAX93294.1 - 0.00033 20.6 0.1 0.00044 20.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Ribosomal_L21e PF01157.18 EAX93294.1 - 0.03 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L21e DUF1564 PF07600.11 EAX93295.1 - 0.0028 17.4 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) DUF410 PF04190.13 EAX93296.1 - 2e-13 50.8 0.3 3e-10 40.4 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF410) ubiquitin PF00240.23 EAX93297.1 - 0.00052 19.7 0.1 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family PDZ_2 PF13180.6 EAX93297.1 - 0.12 12.7 0.7 21 5.6 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Gly_rich PF12810.7 EAX93298.1 - 2.1e-25 90.0 37.9 2.7e-25 89.7 37.9 1.0 1 0 0 1 1 1 1 Glycine rich protein HAD_2 PF13419.6 EAX93299.1 - 1.3e-19 71.0 0.0 1.9e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX93299.1 - 2.4e-07 31.3 0.0 6.3e-07 29.9 0.0 1.6 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX93299.1 - 2.3e-06 27.5 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAX93299.1 - 0.0057 16.7 0.0 0.57 10.3 0.0 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HpcH_HpaI PF03328.14 EAX93300.1 - 2.6e-42 144.4 0.4 3.4e-42 144.1 0.4 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EAX93300.1 - 4.3e-13 49.1 0.9 2.9e-07 30.0 0.1 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Ribosomal_L21e PF01157.18 EAX93301.1 - 4.9e-38 129.0 0.3 6.9e-38 128.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Methyltransf_28 PF02636.17 EAX93302.1 - 0.048 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HEAT PF02985.22 EAX93302.1 - 0.076 13.3 0.0 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat Profilin PF00235.19 EAX93303.1 - 5.7e-11 42.8 0.6 6.8e-11 42.5 0.6 1.0 1 0 0 1 1 1 1 Profilin UQ_con PF00179.26 EAX93304.1 - 1.8e-21 76.3 0.1 2.1e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAX93304.1 - 0.024 14.9 0.4 0.027 14.7 0.4 1.3 1 1 0 1 1 1 0 RWD domain DUF2407_C PF13373.6 EAX93305.1 - 2e-06 28.0 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EAX93305.1 - 5e-05 23.0 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX93305.1 - 0.00017 21.4 0.2 0.00017 21.4 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 EAX93305.1 - 0.0046 17.1 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain Rad60-SLD_2 PF13881.6 EAX93305.1 - 0.023 14.8 0.1 0.067 13.3 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ank_2 PF12796.7 EAX93306.1 - 1.1e-05 25.9 0.1 0.013 16.0 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93306.1 - 0.00017 21.8 0.1 2.9 8.7 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EAX93306.1 - 0.0089 16.6 0.1 5.6 7.7 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93306.1 - 0.54 10.3 11.8 0.059 13.3 4.8 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF3447) Thioredoxin PF00085.20 EAX93307.1 - 8.5e-15 54.6 2.8 1.5e-13 50.6 0.3 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX93307.1 - 3.9e-06 27.3 0.5 1.8e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain ERp29 PF07749.12 EAX93307.1 - 2.2e-05 25.3 0.6 0.00011 23.0 0.6 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.6 EAX93307.1 - 0.0026 17.9 0.3 0.0065 16.6 0.3 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EAX93307.1 - 0.0026 17.6 0.2 0.0091 15.9 0.1 1.9 2 0 0 2 2 2 1 AhpC/TSA family Glyco_transf_24 PF18404.1 EAX93308.1 - 8.6e-18 64.7 0.6 2.9e-17 63.0 0.6 1.8 1 1 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_13 PF18401.1 EAX93308.1 - 0.0071 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAX93308.1 - 0.028 14.0 0.4 0.058 12.9 0.4 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF4368 PF14287.6 EAX93309.1 - 0.077 13.3 1.2 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) PspA_IM30 PF04012.12 EAX93309.1 - 0.23 11.0 1.4 0.23 11.0 0.1 1.5 2 0 0 2 2 2 0 PspA/IM30 family Lipoprotein_21 PF14041.6 EAX93310.1 - 0.068 13.3 0.0 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 LppP/LprE lipoprotein WD40 PF00400.32 EAX93312.1 - 0.002 18.9 0.3 0.16 12.9 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Homeodomain PF00046.29 EAX93312.1 - 1.2 9.0 5.6 0.85 9.5 2.4 2.4 2 0 0 2 2 2 0 Homeodomain Glyco_tran_10_N PF17039.5 EAX93315.1 - 0.003 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Pox_D5 PF03288.16 EAX93316.1 - 4.5e-05 23.9 2.4 0.00027 21.4 2.4 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4108 PF13390.6 EAX93317.1 - 3.1e-59 199.0 7.2 3.4e-59 198.9 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX93318.1 - 4.2e-39 132.9 1.0 7.5e-39 132.1 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX93318.1 - 0.025 15.2 0.3 0.082 13.5 0.0 2.0 3 0 0 3 3 3 0 Parathyroid hormone family DUF3839 PF12943.7 EAX93319.1 - 3e-151 501.7 11.8 3.7e-151 501.3 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX93319.1 - 0.11 12.9 6.5 0.81 10.2 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX93322.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX93323.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX93324.1 - 1.6e-24 85.7 12.1 1.6e-24 85.7 12.1 4.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93324.1 - 3.7e-18 65.7 4.2 7.9e-11 42.3 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93324.1 - 6.7e-18 65.1 15.2 6.3e-10 39.5 0.8 3.9 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93324.1 - 5e-15 54.1 7.9 0.0025 18.1 0.1 6.3 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.30 EAX93324.1 - 8.2e-13 48.2 6.9 1.9e-05 24.9 0.1 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX93324.1 - 3.2e-09 36.9 4.3 0.011 16.0 0.1 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) CEP44 PF15007.6 EAX93324.1 - 0.27 11.4 2.1 5.7 7.1 0.1 3.7 4 1 1 5 5 5 0 Centrosomal spindle body, CEP44 ERM PF00769.19 EAX93325.1 - 2.8e-05 24.0 37.4 2.8e-05 24.0 37.4 14.0 1 1 12 13 13 13 4 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 EAX93325.1 - 0.00023 21.2 14.7 0.00023 21.2 14.7 21.3 4 3 16 21 21 21 5 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EAX93325.1 - 0.00025 21.6 33.2 0.00062 20.3 3.4 22.8 2 2 18 21 21 21 6 Apg6 coiled-coil region CALCOCO1 PF07888.11 EAX93325.1 - 0.00035 19.6 54.5 0.00035 19.6 54.5 11.5 2 2 9 12 12 12 3 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EAX93325.1 - 0.00055 18.9 28.6 0.00055 18.9 28.6 17.6 3 3 15 19 19 19 7 Spc7 kinetochore protein GAS PF13851.6 EAX93325.1 - 0.0023 17.3 19.1 0.0023 17.3 19.1 18.8 4 3 14 19 19 19 6 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EAX93325.1 - 0.0065 16.7 13.7 0.0065 16.7 13.7 23.4 4 3 15 23 23 23 4 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EAX93325.1 - 0.0065 16.7 21.4 0.0065 16.7 21.4 18.2 4 3 10 17 17 17 7 Autophagy protein 16 (ATG16) Xlink PF00193.17 EAX93325.1 - 0.25 11.8 1.8 1.4 9.3 0.2 3.0 2 0 0 2 2 2 0 Extracellular link domain DUF3839 PF12943.7 EAX93326.1 - 1.7e-155 515.6 12.6 1.9e-155 515.4 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX93326.1 - 0.31 11.4 2.6 0.5 10.7 1.0 2.1 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX93326.1 - 2.7 8.5 6.6 3.4 8.2 0.4 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX93327.1 - 5.5e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX93328.1 - 9.8e-120 398.5 11.1 1.2e-119 398.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX93328.1 - 0.042 14.3 1.3 11 6.6 0.0 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF29 PF01724.16 EAX93328.1 - 0.049 13.9 0.1 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 LD_cluster2 PF18163.1 EAX93328.1 - 0.12 11.9 0.1 0.64 9.5 0.0 2.0 1 1 1 2 2 2 0 SLOG cluster2 NTP_transf_6 PF06042.11 EAX93328.1 - 0.15 11.9 1.3 0.45 10.4 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX93329.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Furin-like_2 PF15913.5 EAX93334.1 - 0.00052 20.2 15.3 0.00052 20.2 15.3 2.3 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich DHHC PF01529.20 EAX93336.1 - 1.7e-21 76.7 1.8 1.7e-21 76.7 1.8 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase TrmO PF01980.16 EAX93337.1 - 1.7e-34 118.6 0.0 2.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 tRNA-methyltransferase O Peptidase_C1 PF00112.23 EAX93338.1 - 1e-54 185.9 0.8 2e-54 185.0 0.8 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX93338.1 - 0.15 10.8 1.9 0.45 9.2 0.5 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Ank_2 PF12796.7 EAX93339.1 - 1.5e-14 54.3 3.7 0.0003 21.3 0.0 4.3 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93339.1 - 5.3e-13 49.2 4.6 0.00035 21.1 0.1 4.6 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93339.1 - 6.1e-09 35.4 3.7 0.13 12.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX93339.1 - 9.2e-07 29.0 0.0 9.4 6.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93339.1 - 0.015 15.7 2.9 15 6.3 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat RICTOR_M PF14666.6 EAX93339.1 - 0.042 13.6 0.3 0.15 11.8 0.3 2.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Ank_2 PF12796.7 EAX93340.1 - 1.4e-06 28.7 0.0 2.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93340.1 - 2.1e-05 24.6 0.2 0.082 13.5 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX93340.1 - 0.00068 20.1 0.2 0.11 13.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93340.1 - 0.0075 16.6 0.2 2.8 8.4 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93340.1 - 0.011 16.1 0.0 0.58 10.7 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 EAX93341.1 - 2.8e-07 31.0 0.3 0.00035 21.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX93341.1 - 5.8e-06 26.5 0.1 0.036 14.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX93341.1 - 1.5e-05 25.4 0.2 0.07 13.7 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93341.1 - 0.021 15.3 1.3 2.9 8.7 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat Arg_repressor PF01316.21 EAX93341.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF3447 PF11929.8 EAX93342.1 - 9.6e-07 28.7 0.9 3.8e-06 26.8 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) DUF2513 PF10711.9 EAX93342.1 - 0.095 13.0 0.6 0.2 11.9 0.3 1.7 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) Ank_2 PF12796.7 EAX93342.1 - 0.16 12.6 0.1 0.48 11.1 0.0 1.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX93343.1 - 2e-42 143.6 0.0 1.2e-17 64.2 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93343.1 - 1.3e-23 83.0 0.0 1.4e-07 31.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93343.1 - 2.6e-21 75.4 0.0 5.7e-08 32.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX93343.1 - 4.9e-21 74.2 0.0 2.6e-05 24.5 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX93343.1 - 1.1e-17 62.2 0.0 0.00055 20.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat DBD_Tnp_Hermes PF10683.9 EAX93343.1 - 0.14 11.9 0.1 28 4.5 0.0 3.0 1 1 2 3 3 3 0 Hermes transposase DNA-binding domain PilZ_2 PF16823.5 EAX93343.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor Ank_2 PF12796.7 EAX93344.1 - 2.5e-71 236.3 13.5 1.1e-21 77.1 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93344.1 - 1.7e-54 181.5 1.3 1.3e-13 51.1 0.0 6.3 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93344.1 - 4.8e-43 144.7 7.3 3.1e-08 33.7 0.0 8.2 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93344.1 - 6.9e-40 130.5 2.2 0.00018 21.6 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EAX93344.1 - 1.1e-39 133.2 1.6 1.2e-06 28.7 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat UCH PF00443.29 EAX93344.1 - 0.036 13.5 0.2 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase SnAPC_2_like PF11035.8 EAX93344.1 - 0.12 12.5 2.9 8.1 6.5 1.4 2.1 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF3839 PF12943.7 EAX93346.1 - 3e-25 89.1 4.0 4.3e-25 88.6 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX93346.1 - 0.037 14.3 0.7 0.14 12.4 0.1 2.0 1 1 1 2 2 2 0 PRD domain HTH_19 PF12844.7 EAX93346.1 - 0.082 12.9 0.5 0.16 12.0 0.4 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Trypan_PARP PF05887.11 EAX93347.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX93347.1 - 2 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX93348.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93348.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDE_Tnp_4 PF13359.6 EAX93349.1 - 4.2e-34 117.5 0.0 6.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX93349.1 - 2e-07 30.9 0.6 1.8e-06 27.8 0.6 2.1 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX93349.1 - 4.7e-05 23.0 0.8 0.0013 18.4 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 EAX93349.1 - 0.096 13.1 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain Ank_4 PF13637.6 EAX93350.1 - 5.1e-120 390.4 36.5 4.2e-13 49.5 0.0 13.4 1 1 14 16 16 16 15 Ankyrin repeats (many copies) Ank PF00023.30 EAX93350.1 - 3.9e-109 352.8 23.4 1.9e-08 34.4 0.1 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_2 PF12796.7 EAX93350.1 - 1.2e-102 336.7 52.7 1.7e-15 57.3 0.9 9.2 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93350.1 - 7.1e-88 277.9 27.6 7.9e-06 25.9 0.1 16.0 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 EAX93350.1 - 1.1e-64 213.6 30.9 3.6e-09 36.7 1.6 10.7 3 2 5 11 11 11 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93350.1 - 8.7e-25 86.5 8.2 8.7e-25 86.5 8.2 6.8 4 1 4 8 8 8 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX93350.1 - 1.4e-12 47.7 3.9 0.69 10.2 0.0 8.4 1 1 9 11 11 11 4 N terminal of Calcineurin-like phosphoesterase Ribosomal_S6 PF01250.17 EAX93350.1 - 2.8e-08 33.9 22.6 0.87 9.9 0.3 8.9 1 1 7 10 10 10 3 Ribosomal protein S6 GATase_7 PF13537.6 EAX93350.1 - 2.1e-05 24.4 0.0 60 3.6 0.0 6.8 6 1 1 7 7 7 0 Glutamine amidotransferase domain PDDEXK_2 PF12784.7 EAX93350.1 - 0.00012 21.7 19.9 0.15 11.6 1.0 4.5 2 1 2 4 4 4 3 PD-(D/E)XK nuclease family transposase Shigella_OspC PF06128.11 EAX93350.1 - 0.00025 20.9 45.6 0.41 10.3 0.6 8.3 2 1 5 9 9 9 6 Shigella flexneri OspC protein MTES_1575 PF18741.1 EAX93350.1 - 0.00082 19.5 2.8 12 6.1 0.1 5.2 3 1 3 6 6 6 0 REase_MTES_1575 RNase_PH_C PF03725.15 EAX93350.1 - 0.024 14.7 11.8 23 5.1 0.1 8.3 7 4 4 11 11 11 0 3' exoribonuclease family, domain 2 HPPK PF01288.20 EAX93350.1 - 0.24 11.9 19.6 6.1 7.4 1.2 5.2 2 2 3 5 5 5 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ATPase PF06745.13 EAX93350.1 - 0.24 10.7 6.3 2.6 7.4 0.2 3.7 1 1 2 3 3 3 0 KaiC PH_8 PF15409.6 EAX93350.1 - 1.2 9.4 12.4 41 4.5 0.0 7.1 4 3 5 9 9 9 0 Pleckstrin homology domain DUF2149 PF09919.9 EAX93350.1 - 4.8 7.5 15.3 1.6e+02 2.7 0.1 7.2 2 2 7 11 11 11 0 Uncharacterized conserved protein (DUF2149) Ank_2 PF12796.7 EAX93351.1 - 0.062 13.9 0.0 0.17 12.5 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Rota_NSP4 PF01452.16 EAX93352.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein Peptidase_C28 PF05408.11 EAX93352.1 - 0.12 12.1 1.5 1.1 8.9 0.1 2.5 2 1 1 3 3 3 0 Foot-and-mouth virus L-proteinase PP2C_C PF07830.13 EAX93353.1 - 0.48 10.9 1.9 19 5.8 0.1 3.4 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Beta_elim_lyase PF01212.21 EAX93354.1 - 9.7e-55 185.9 0.0 1.2e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EAX93354.1 - 0.0033 16.4 0.0 0.005 15.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EAX93354.1 - 0.045 12.5 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pyridoxal_deC PF00282.19 EAX93354.1 - 0.066 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ank_2 PF12796.7 EAX93356.1 - 2.3e-25 89.0 3.4 2.6e-09 37.5 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93356.1 - 1.1e-20 73.7 1.8 2.4e-09 37.6 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93356.1 - 1.1e-19 70.2 0.4 5.4e-08 33.0 0.0 4.6 3 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93356.1 - 1.5e-17 63.1 1.8 0.0017 18.7 0.3 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX93356.1 - 1.5e-17 61.8 0.4 0.002 18.5 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat HECW_N PF16562.5 EAX93356.1 - 0.13 12.1 1.0 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF4051 PF13260.6 EAX93356.1 - 2.1 8.1 3.5 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Prominin PF05478.11 EAX93356.1 - 6.1 4.7 14.5 10 3.9 14.5 1.3 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 EAX93356.1 - 7.9 6.5 8.6 2.2 8.3 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rho_N PF07498.12 EAX93357.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF563 PF04577.14 EAX93358.1 - 2.1e-26 93.4 0.3 4.4e-26 92.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LRV PF01816.17 EAX93359.1 - 0.73 10.4 15.7 41 4.9 0.2 6.4 7 0 0 7 7 7 0 Leucine rich repeat variant DUF2786 PF10979.8 EAX93359.1 - 2.3 8.2 3.4 1.4e+02 2.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2786) DUF4108 PF13390.6 EAX93360.1 - 5.4e-63 211.2 5.8 6e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX93361.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX93362.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93362.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93362.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93362.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93362.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93362.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93362.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93362.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX93362.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93362.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93362.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93362.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX93363.1 - 7.2e-41 138.6 0.1 7.2e-41 138.6 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3552 PF12072.8 EAX93363.1 - 0.0075 15.7 7.0 0.014 14.8 7.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Acyl_transf_2 PF02273.15 EAX93363.1 - 0.037 13.3 0.1 0.14 11.3 0.1 1.8 1 1 1 2 2 2 0 Acyl transferase RRP36 PF06102.12 EAX93363.1 - 0.064 13.2 6.4 0.13 12.2 6.4 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF3839 PF12943.7 EAX93364.1 - 4e-120 399.7 11.3 5.3e-120 399.3 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX93364.1 - 0.036 14.5 3.2 2 8.9 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX93364.1 - 0.055 13.9 0.3 0.084 13.3 0.3 1.3 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX93364.1 - 0.24 12.0 1.5 0.31 11.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX93365.1 - 8.1e-40 135.2 0.3 2e-39 133.9 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX93365.1 - 0.0096 16.5 0.1 0.027 15.1 0.0 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX93366.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93366.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93366.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93366.1 - 0.00016 21.7 3.4 0.0004 20.4 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93366.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93366.1 - 0.0013 18.6 0.5 0.0026 17.6 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93366.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93366.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX93366.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93366.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93366.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93366.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX93367.1 - 0.19 11.7 2.1 0.36 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pkinase PF00069.25 EAX93368.1 - 9.3e-16 58.0 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93368.1 - 6.5e-14 51.8 0.0 1.3e-13 50.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Imm15 PF15561.6 EAX93368.1 - 0.037 14.3 0.3 0.056 13.7 0.3 1.3 1 0 0 1 1 1 0 Immunity protein 15 DUF3885 PF13021.6 EAX93368.1 - 0.063 13.4 0.8 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Rep_Org_C PF06926.11 EAX93368.1 - 0.17 12.2 4.4 0.34 11.3 0.4 2.7 1 1 1 3 3 3 0 Putative replisome organiser protein C-terminus Toxin_R_bind_C PF07951.12 EAX93369.1 - 0.005 16.5 3.8 0.018 14.7 0.3 2.7 2 1 1 3 3 3 1 Clostridium neurotoxin, C-terminal receptor binding Herpes_IE2_3 PF03361.14 EAX93369.1 - 0.019 14.8 1.0 0.47 10.3 0.2 2.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX93369.1 - 0.89 9.9 7.9 4.1 7.7 0.8 3.0 3 0 0 3 3 3 0 PPP5 TPR repeat region CBM_4_9 PF02018.17 EAX93371.1 - 0.0045 17.3 1.1 0.4 11.0 0.0 3.7 4 0 0 4 4 4 1 Carbohydrate binding domain EphA2_TM PF14575.6 EAX93371.1 - 0.0064 17.3 0.1 0.1 13.5 0.0 2.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 EAX93371.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Insulin_TMD PF17870.1 EAX93371.1 - 0.13 12.4 4.1 0.31 11.1 4.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PPP1R26_N PF15740.5 EAX93371.1 - 0.13 10.8 1.0 0.18 10.4 1.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus NVEALA PF14055.6 EAX93371.1 - 0.25 11.3 2.5 0.3 11.1 0.6 2.0 2 0 0 2 2 2 0 NVEALA protein TMEM154 PF15102.6 EAX93371.1 - 0.6 10.0 6.7 0.077 12.9 2.4 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF3494 PF11999.8 EAX93372.1 - 0.14 11.7 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3494) s48_45 PF07422.13 EAX93372.1 - 0.15 12.6 2.7 0.93 10.1 0.2 3.0 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain DUF4625 PF15418.6 EAX93374.1 - 0.074 13.3 5.3 10 6.4 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4625) DUF4384 PF14326.6 EAX93374.1 - 0.19 11.9 4.9 60 3.9 0.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4384) WD40 PF00400.32 EAX93377.1 - 0.00035 21.3 0.1 10 7.2 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93377.1 - 0.0079 16.5 0.0 1 9.7 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAX93377.1 - 0.03 14.3 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat LRR_5 PF13306.6 EAX93378.1 - 7.4e-18 64.7 7.5 8.1e-18 64.6 7.5 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93378.1 - 0.00031 20.5 0.2 0.022 14.5 0.1 2.2 1 1 1 2 2 2 2 Leucine rich repeat zf-Tim10_DDP PF02953.15 EAX93378.1 - 0.19 11.4 6.4 0.48 10.1 2.5 2.8 2 1 1 3 3 3 0 Tim10/DDP family zinc finger LRR_1 PF00560.33 EAX93378.1 - 0.21 12.3 2.7 17 6.5 0.4 3.0 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_5 PF13306.6 EAX93379.1 - 2.3e-50 169.8 42.1 3.8e-27 94.8 10.3 3.8 2 2 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93379.1 - 3.9e-18 64.9 11.9 4.9e-06 26.2 0.1 5.4 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EAX93379.1 - 0.021 15.3 0.2 0.021 15.3 0.2 5.4 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) MSA-2c PF12238.8 EAX93379.1 - 0.052 13.6 2.0 0.078 13.0 2.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Flu_C_NS1 PF03506.13 EAX93379.1 - 0.062 13.3 0.4 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) HEAT PF02985.22 EAX93380.1 - 1e-11 44.1 0.4 0.11 12.8 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 EAX93380.1 - 9.1e-11 42.0 0.2 8.8e-05 22.8 0.0 4.6 2 2 3 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EAX93380.1 - 0.031 14.9 10.4 11 6.7 0.3 5.4 5 2 1 6 6 6 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EAX93380.1 - 1.3 9.2 5.2 6.4 7.0 0.6 3.8 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 GPCR_chapero_1 PF11904.8 EAX93381.1 - 1.1e-08 34.9 0.1 0.00038 20.0 0.0 2.1 1 1 1 2 2 2 2 GPCR-chaperone Ank_5 PF13857.6 EAX93381.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF5498 PF17602.2 EAX93381.1 - 0.075 13.5 0.1 8 7.0 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5498) DAGK_cat PF00781.24 EAX93382.1 - 1.2e-30 105.7 0.0 1.7e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Fe-ADH_2 PF13685.6 EAX93382.1 - 0.0042 16.8 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NAD_kinase PF01513.21 EAX93382.1 - 0.043 13.0 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase Gly-zipper_Omp PF13488.6 EAX93385.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX93385.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX93385.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX93385.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX93385.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif MULE PF10551.9 EAX93386.1 - 0.00025 21.4 0.1 0.0009 19.6 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain WRKY PF03106.15 EAX93386.1 - 0.025 14.8 3.2 0.051 13.8 0.9 2.5 1 1 1 2 2 2 0 WRKY DNA -binding domain WD40 PF00400.32 EAX93388.1 - 3.1e-08 34.2 0.7 4 8.5 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93388.1 - 3.1e-06 27.4 0.1 0.0019 18.5 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EAX93388.1 - 0.0022 18.4 0.0 1.6 9.4 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain CNH PF00780.22 EAX93388.1 - 0.0048 16.5 0.0 0.44 10.1 0.0 2.8 1 1 0 1 1 1 1 CNH domain Fascin PF06268.13 EAX93389.1 - 8.3e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 EAX93389.1 - 3.2e-05 23.7 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 FRG1-like domain FGF PF00167.18 EAX93389.1 - 0.0063 16.6 0.1 0.038 14.1 0.0 1.9 1 1 1 2 2 2 1 Fibroblast growth factor Ank_2 PF12796.7 EAX93390.1 - 4.2e-22 78.5 8.8 4.1e-12 46.5 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93390.1 - 3e-18 64.0 15.9 0.00059 20.1 0.1 9.3 7 1 2 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 EAX93390.1 - 5.6e-14 52.3 3.2 1e-05 26.0 0.0 5.5 4 2 1 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93390.1 - 4.4e-13 49.0 2.9 4.4e-13 49.0 2.9 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX93390.1 - 5.4e-13 48.9 5.2 0.048 14.0 0.0 7.2 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX93390.1 - 1.3e-08 34.9 7.3 0.0077 16.6 0.1 6.3 6 1 1 7 7 7 2 Ankyrin repeat His_kinase PF06580.13 EAX93390.1 - 0.079 13.3 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Histidine kinase SR-25 PF10500.9 EAX93390.1 - 2.4 7.7 29.6 3.8 7.1 29.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pro-NT_NN PF07421.11 EAX93392.1 - 0.0068 16.7 0.9 0.007 16.6 0.9 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor MAJIN PF15077.6 EAX93392.1 - 3.8 7.2 9.3 4 7.2 9.3 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein GPS2_interact PF15784.5 EAX93393.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93393.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain T5orf172 PF10544.9 EAX93394.1 - 2.6e-06 27.9 0.2 6.7e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX93394.1 - 0.012 15.4 0.2 0.057 13.3 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain Baculo_ME53 PF06061.11 EAX93394.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF3839 PF12943.7 EAX93395.1 - 1.4e-152 506.0 13.4 1.8e-152 505.6 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX93395.1 - 0.15 11.9 1.1 0.46 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX93395.1 - 0.98 9.9 5.7 2.2 8.8 0.8 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX93397.1 - 1.7e-73 246.1 4.8 2.1e-73 245.8 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX93397.1 - 0.15 10.5 1.0 0.21 10.0 1.0 1.1 1 0 0 1 1 1 0 Lipoxygenase PTR PF12789.7 EAX93400.1 - 4.4e-11 42.7 20.0 0.00091 19.2 2.0 5.4 4 1 1 5 5 5 3 Phage tail repeat like HIP1_clath_bdg PF16515.5 EAX93400.1 - 0.089 13.4 0.3 0.4 11.3 0.3 2.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MazG PF03819.17 EAX93400.1 - 0.12 12.5 0.1 0.72 10.1 0.1 2.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain EpuA PF11772.8 EAX93400.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4795 PF16043.5 EAX93400.1 - 8.6 5.9 13.0 1.7 8.2 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) DDE_Tnp_4 PF13359.6 EAX93404.1 - 2.3e-31 108.6 0.0 3.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX93404.1 - 2.4e-08 33.9 0.1 1.2e-07 31.6 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain MatE PF01554.18 EAX93405.1 - 6.9e-15 55.1 8.5 7.3e-15 55.0 6.9 1.7 2 0 0 2 2 2 1 MatE DUF2070 PF09843.9 EAX93405.1 - 0.018 13.3 5.4 0.023 13.0 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PHO4 PF01384.20 EAX93405.1 - 0.075 12.1 4.4 0.11 11.5 4.4 1.2 1 0 0 1 1 1 0 Phosphate transporter family PNTB PF02233.16 EAX93405.1 - 0.13 11.1 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit DUF2975 PF11188.8 EAX93405.1 - 0.14 12.1 6.1 0.44 10.4 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) SUR7 PF06687.12 EAX93405.1 - 0.17 11.5 10.2 0.08 12.6 2.6 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF2393 PF09624.10 EAX93405.1 - 0.25 11.3 3.7 0.98 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) MctB PF11382.8 EAX93405.1 - 0.28 10.9 0.0 0.6 9.8 0.0 1.5 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB TatC PF00902.18 EAX93405.1 - 0.56 10.0 10.9 0.077 12.8 4.4 2.0 1 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) MARVEL PF01284.23 EAX93405.1 - 7.6 6.6 15.8 0.11 12.6 2.2 2.8 2 1 0 2 2 2 0 Membrane-associating domain MatE PF01554.18 EAX93406.1 - 2.3e-15 56.6 6.3 2.3e-15 56.6 6.3 1.6 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EAX93406.1 - 0.00061 19.9 3.2 0.00061 19.9 3.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Methyltransf_11 PF08241.12 EAX93407.1 - 1.4e-18 67.3 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX93407.1 - 3.3e-17 63.0 0.0 9.7e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX93407.1 - 9.5e-13 48.7 0.0 8.3e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX93407.1 - 1.4e-11 44.4 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAX93407.1 - 4.4e-09 36.0 0.0 6.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAX93407.1 - 3e-06 27.2 0.0 5.6e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAX93407.1 - 3.8e-06 26.4 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EAX93407.1 - 3.8e-06 26.7 0.0 5.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 EAX93407.1 - 0.00044 20.0 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.16 EAX93407.1 - 0.0021 16.7 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EAX93407.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EAX93407.1 - 0.022 14.6 0.0 0.43 10.4 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase Pkinase_Tyr PF07714.17 EAX93408.1 - 8e-60 202.3 0.0 1.2e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX93408.1 - 2.5e-57 194.2 0.0 4.8e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAX93408.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX93408.1 - 0.00018 20.5 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX93408.1 - 0.00024 20.7 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAX93408.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank PF00023.30 EAX93409.1 - 2.4e-24 84.7 9.3 9.6e-07 29.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAX93409.1 - 1.5e-23 82.9 6.3 3.5e-07 30.6 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93409.1 - 7.3e-23 81.0 2.3 1.7e-14 54.1 0.3 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX93409.1 - 2.8e-21 75.3 2.9 3.8e-08 33.4 0.0 3.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93409.1 - 2.9e-21 73.3 6.5 1.2e-05 25.3 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ribosomal_S6 PF01250.17 EAX93409.1 - 0.0052 17.0 0.2 0.38 11.0 0.0 3.1 1 1 3 4 4 4 1 Ribosomal protein S6 Shigella_OspC PF06128.11 EAX93409.1 - 0.011 15.5 0.7 0.06 13.1 0.3 2.0 1 1 2 3 3 3 0 Shigella flexneri OspC protein DUF348 PF03990.14 EAX93409.1 - 0.069 12.9 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Mic1 PF07035.12 EAX93409.1 - 0.081 12.6 0.3 0.34 10.6 0.1 2.0 1 1 2 3 3 3 0 Colon cancer-associated protein Mic1-like Xpo1 PF08389.12 EAX93410.1 - 6.6e-26 91.2 2.7 4.3e-25 88.5 0.3 3.5 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_C PF08767.11 EAX93410.1 - 1.1e-13 51.0 3.1 9.7e-13 48.0 0.3 3.3 3 2 0 3 3 3 1 CRM1 C terminal CRM1_repeat_3 PF18787.1 EAX93410.1 - 9.5e-05 22.4 0.0 0.00032 20.7 0.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 EAX93410.1 - 0.00041 20.2 5.1 0.0037 17.1 0.2 4.5 5 1 0 5 5 5 1 Importin-beta N-terminal domain Inhibitor_I67 PF11405.8 EAX93410.1 - 0.052 13.8 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Bromelain inhibitor VI 2H-phosphodiest PF08975.10 EAX93410.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) WHIM1 PF15612.6 EAX93410.1 - 0.16 11.6 0.7 0.51 9.9 0.3 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 Cnd1 PF12717.7 EAX93410.1 - 0.25 11.4 3.5 1.5e+02 2.4 0.0 5.0 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX93410.1 - 0.81 10.1 4.0 88 3.8 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat TMP PF05017.14 EAX93411.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Cas3_C PF18395.1 EAX93412.1 - 0.012 16.1 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 Cas3 C-terminal domain IPT PF01745.16 EAX93412.1 - 0.072 12.5 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase LRR_8 PF13855.6 EAX93413.1 - 6.3e-37 125.1 33.3 2.6e-14 52.7 5.1 4.8 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EAX93413.1 - 1.7e-23 82.3 21.3 2.4e-07 30.9 3.0 5.8 2 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX93413.1 - 2.3e-16 59.8 7.1 3.9e-08 33.0 0.1 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 EAX93413.1 - 2.5e-09 37.2 5.5 6.2e-09 35.9 3.1 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EAX93413.1 - 4.5e-05 23.2 7.9 3.3 8.0 0.4 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EAX93413.1 - 0.0001 22.3 7.9 3.8 8.4 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat XRN_M PF17846.1 EAX93413.1 - 0.014 14.4 2.6 0.02 13.9 2.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain RNA_pol_Rpc4 PF05132.14 EAX93413.1 - 0.053 14.0 2.0 0.077 13.4 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rtf2 PF04641.12 EAX93413.1 - 1.2 8.5 8.2 1.9 7.8 8.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 EAX93413.1 - 4.4 6.0 7.9 5.9 5.5 7.9 1.1 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 EAX93413.1 - 5.9 6.2 20.5 8.2 5.7 20.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ank_2 PF12796.7 EAX93414.1 - 4.9e-29 100.7 4.4 5.2e-06 27.0 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93414.1 - 6.6e-23 80.8 5.3 5.1e-05 23.7 0.0 7.6 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93414.1 - 4.5e-20 69.6 7.7 0.04 14.4 0.1 10.4 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 EAX93414.1 - 2.9e-11 43.4 1.8 0.0093 16.3 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93414.1 - 5.6e-11 42.4 0.7 0.84 10.2 0.1 7.4 7 1 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 EAX93414.1 - 2.8e-07 30.4 0.8 2.8e-07 30.4 0.8 4.9 7 1 0 7 7 7 1 Domain of unknown function (DUF3447) RestrictionSfiI PF11487.8 EAX93414.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 Type II restriction enzyme SfiI DUF3081 PF11280.8 EAX93414.1 - 1.4 8.8 5.2 0.38 10.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3081) Gelsolin PF00626.22 EAX93415.1 - 6.5e-30 102.9 0.0 1.9e-13 50.1 0.0 3.1 3 0 0 3 3 3 3 Gelsolin repeat DUF4106 PF13388.6 EAX93416.1 - 3.9e-261 866.4 33.8 3.9e-261 866.4 33.8 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX93416.1 - 0.011 16.1 3.1 0.071 13.4 0.3 3.0 3 0 0 3 3 3 0 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX93416.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DUF3839 PF12943.7 EAX93417.1 - 4.1e-156 517.6 12.4 4.8e-156 517.3 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX93417.1 - 1 9.9 3.6 3.3 8.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX93417.1 - 6.8 7.2 7.2 4 7.9 0.4 2.9 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX93419.1 - 8e-10 38.6 6.8 1.2e-08 34.9 1.4 4.9 5 1 1 6 6 6 2 Phage tail repeat like ATR13 PF16829.5 EAX93419.1 - 0.65 10.4 5.2 1.3 9.4 2.5 2.4 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector DUF4795 PF16043.5 EAX93419.1 - 2.5 7.7 15.4 7.3 6.1 3.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) LRR_5 PF13306.6 EAX93420.1 - 3.5e-128 421.4 69.6 3.1e-28 98.3 11.5 7.1 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93420.1 - 4.6e-05 23.1 7.2 1.9 8.3 0.2 7.2 6 1 0 6 6 6 1 Leucine rich repeat PI-PLC-X PF00388.19 EAX93420.1 - 8.8e-05 22.1 1.1 4.8 6.8 0.0 5.7 7 1 0 7 7 7 2 Phosphatidylinositol-specific phospholipase C, X domain MPTase-PolyVal PF18818.1 EAX93420.1 - 0.04 14.0 0.2 5.9 7.0 0.0 3.5 3 0 0 3 3 3 0 Metallopeptidase superfamily domain Microcin PF03526.13 EAX93420.1 - 0.25 11.2 4.1 5 7.0 0.0 3.9 4 0 0 4 4 4 0 Colicin E1 (microcin) immunity protein LRR_5 PF13306.6 EAX93421.1 - 3.3e-122 402.1 59.8 1.3e-26 93.1 7.6 6.5 1 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93421.1 - 0.00016 21.4 2.0 2.9 7.7 0.0 5.9 6 1 1 7 7 7 3 Leucine rich repeat Pentapeptide_4 PF13599.6 EAX93421.1 - 0.0025 18.0 2.0 12 6.2 0.0 5.9 6 3 0 6 6 6 1 Pentapeptide repeats (9 copies) DP-EP PF08985.11 EAX93422.1 - 0.068 13.3 0.3 0.71 10.1 0.0 2.4 2 1 0 2 2 2 0 DP-EP family ECSCR PF15820.5 EAX93423.1 - 0.0011 18.7 0.5 0.0026 17.5 0.5 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Shisa PF13908.6 EAX93423.1 - 0.0013 19.0 0.2 0.0023 18.2 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.6 EAX93423.1 - 0.0048 17.4 2.9 0.014 15.9 3.0 1.7 2 0 0 2 2 2 1 FAM163 family MAP17 PF15807.5 EAX93423.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 E2F_CC-MB PF16421.5 EAX93423.1 - 0.054 13.9 0.3 4.2 7.8 0.0 2.9 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain EphA2_TM PF14575.6 EAX93423.1 - 0.1 13.5 2.2 0.23 12.4 1.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EAX93423.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Corona_NS3b PF03053.14 EAX93423.1 - 4.7 6.9 6.2 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 ORF3b coronavirus protein DUF563 PF04577.14 EAX93424.1 - 7.1e-30 104.7 0.0 1.3e-29 103.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) QueH PF02677.14 EAX93425.1 - 0.085 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH Ras PF00071.22 EAX93426.1 - 1.3e-42 145.1 0.7 1.6e-42 144.9 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX93426.1 - 2.5e-33 114.8 0.3 3.5e-33 114.4 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX93426.1 - 1.8e-14 53.6 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX93426.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX93426.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAX93426.1 - 1e-05 25.1 0.0 0.00041 19.9 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAX93426.1 - 3.3e-05 23.5 0.1 0.00016 21.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX93426.1 - 4.7e-05 23.4 0.1 0.06 13.3 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EAX93426.1 - 0.00023 20.6 0.1 0.00062 19.2 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EAX93426.1 - 0.00032 20.6 0.7 0.00086 19.3 0.2 2.0 2 1 1 3 3 3 1 NTPase PduV-EutP PF10662.9 EAX93426.1 - 0.00079 19.2 0.5 0.016 14.9 0.5 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EAX93426.1 - 0.0015 17.9 0.0 0.0043 16.5 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein CTP_transf_3 PF02348.19 EAX93426.1 - 0.005 16.8 0.7 0.019 14.9 0.1 1.9 1 1 0 2 2 2 1 Cytidylyltransferase MMR_HSR1_Xtn PF16897.5 EAX93426.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 EAX93426.1 - 0.016 15.5 0.1 0.023 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX93426.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAX93426.1 - 0.061 13.7 0.1 0.12 12.8 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EAX93426.1 - 0.12 12.4 0.0 3.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IBD PF10416.9 EAX93427.1 - 5.8e-29 100.7 0.1 8.1e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Terminase_3 PF04466.13 EAX93427.1 - 0.0049 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Phage terminase large subunit DUF1048 PF06304.11 EAX93427.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) START PF01852.19 EAX93428.1 - 2.2e-08 33.8 0.0 1.3e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 START domain Aminotran_5 PF00266.19 EAX93429.1 - 4e-16 58.9 0.0 6.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EAX93429.1 - 5.9e-12 45.5 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EAX93429.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain DUF3447 PF11929.8 EAX93430.1 - 4.8e-36 122.6 8.7 4.8e-36 122.6 8.7 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93430.1 - 1.6e-32 111.9 25.1 1.3e-13 51.3 1.8 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93430.1 - 1.2e-30 104.6 1.3 1.2e-05 25.5 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX93430.1 - 1.4e-25 89.3 2.6 7.8e-09 35.9 0.0 6.7 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93430.1 - 1.6e-24 83.3 6.8 0.0011 19.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX93430.1 - 1.2e-18 66.9 7.1 6.4e-07 29.5 1.7 5.3 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Nitroreductase PF00881.24 EAX93432.1 - 5.9e-24 85.0 0.0 6.7e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX93432.1 - 2.1e-05 24.2 3.8 0.078 12.5 0.7 2.7 1 1 1 2 2 2 2 Putative TM nitroreductase DUF2148 PF09918.9 EAX93432.1 - 0.022 14.8 0.2 0.042 13.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Methyltransf_15 PF09445.10 EAX93433.1 - 6.8e-07 29.0 0.2 1.4e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 EAX93433.1 - 1.8e-06 27.2 0.4 8.1e-06 25.1 0.2 2.1 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EAX93433.1 - 2e-06 28.4 0.1 9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX93433.1 - 2.8e-06 27.2 0.2 5.5e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX93433.1 - 9e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAX93433.1 - 0.00052 19.6 0.1 0.00095 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EAX93433.1 - 0.0021 18.6 0.0 0.0059 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAX93433.1 - 0.0022 17.4 0.4 0.0041 16.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EAX93433.1 - 0.017 14.4 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EAX93433.1 - 0.043 13.8 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EAX93433.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EAX93433.1 - 0.092 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 EAX93433.1 - 0.16 12.7 0.1 0.4 11.5 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_99 PF16317.5 EAX93434.1 - 2e-44 152.1 11.2 2.4e-44 151.9 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 EAX93434.1 - 7.4e-10 38.2 5.0 9.4e-10 37.8 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ank_2 PF12796.7 EAX93435.1 - 7.7e-95 311.6 50.7 2.6e-16 60.0 2.5 6.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93435.1 - 5.5e-84 273.2 29.1 3.1e-07 30.5 0.1 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.6 EAX93435.1 - 4.3e-83 272.3 36.7 1.2e-11 44.6 0.1 9.5 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX93435.1 - 4.8e-76 250.2 22.8 1.3e-11 44.8 0.3 11.4 1 1 11 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93435.1 - 2.3e-54 174.9 35.5 0.00011 22.4 0.0 12.3 12 1 0 12 12 12 11 Ankyrin repeat SCVP PF17619.2 EAX93435.1 - 5.1e-10 40.1 10.8 22 6.0 0.0 8.9 1 1 6 9 9 9 0 Secreted clade V proteins DUF3447 PF11929.8 EAX93435.1 - 1.1e-06 28.4 37.9 0.0087 16.0 0.3 6.2 2 2 6 8 8 8 6 Domain of unknown function (DUF3447) S6PP PF05116.13 EAX93435.1 - 4.8e-05 23.0 0.7 27 4.2 0.0 5.6 1 1 5 7 7 7 0 Sucrose-6F-phosphate phosphohydrolase DUF1456 PF07308.13 EAX93435.1 - 5.6e-05 23.4 0.7 1.3 9.4 0.0 5.8 6 0 0 6 6 6 1 Protein of unknown function (DUF1456) Ufm1 PF03671.14 EAX93435.1 - 0.00022 21.3 2.4 14 5.9 0.0 5.5 4 1 3 7 7 7 0 Ubiquitin fold modifier 1 protein ocr PF08684.10 EAX93435.1 - 0.0027 18.1 15.6 15 6.1 0.2 7.6 2 2 7 10 10 10 0 DNA mimic ocr CPSase_C PF18302.1 EAX93435.1 - 0.027 14.7 0.0 1.7e+03 0.3 0.0 6.5 8 0 0 8 8 6 0 Carbamoyl phosphate synthetase C-terminal domain ELFV_dehydrog_N PF02812.18 EAX93435.1 - 0.03 14.2 7.5 60 3.5 0.1 5.7 2 1 5 8 8 8 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ROQ_II PF18386.1 EAX93435.1 - 0.52 10.2 3.0 31 4.5 0.0 3.5 3 0 0 3 3 3 0 Roquin II domain DUF3819 PF12842.7 EAX93435.1 - 0.71 9.8 3.6 1.2e+02 2.6 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3819) Stap_Strp_toxin PF01123.20 EAX93435.1 - 1.1 10.1 20.2 0.5 11.3 0.3 5.9 2 2 6 8 8 8 0 Staphylococcal/Streptococcal toxin, OB-fold domain BrkDBD PF09607.10 EAX93436.1 - 5.2 6.9 5.1 51 3.7 0.1 2.7 2 0 0 2 2 2 0 Brinker DNA-binding domain MbeD_MobD PF04899.12 EAX93437.1 - 0.62 10.2 10.8 0.69 10.1 0.0 4.4 4 1 0 4 4 4 0 MbeD/MobD like Gly_rich PF12810.7 EAX93438.1 - 1.4e-33 116.9 19.1 1.8e-33 116.5 19.1 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAX93439.1 - 7.2e-37 125.2 3.9 7.2e-37 125.2 3.9 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93439.1 - 4e-18 65.8 0.7 2.5e-13 50.4 0.3 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93439.1 - 1.8e-15 57.0 0.4 1.7e-08 34.8 0.1 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93439.1 - 1.2e-14 54.0 1.7 4.1e-06 27.0 0.1 4.4 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX93439.1 - 2.1e-12 46.0 4.0 9.2e-05 22.6 0.1 5.7 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX93439.1 - 1.7e-11 44.1 0.2 1.8e-10 40.9 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HSP70 PF00012.20 EAX93440.1 - 7.4e-252 836.8 3.7 8.4e-252 836.7 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX93440.1 - 1.9e-15 56.5 0.0 3.8e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EAX93440.1 - 0.00055 19.7 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EAX93440.1 - 0.0052 17.2 0.5 8 6.9 0.0 3.5 3 2 0 3 3 3 2 Cell division protein FtsA StbA PF06406.11 EAX93440.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 StbA protein Pex19 PF04614.12 EAX93440.1 - 0.25 11.1 2.9 0.91 9.2 2.0 2.0 2 0 0 2 2 2 0 Pex19 protein family Ank_2 PF12796.7 EAX93441.1 - 2.9e-45 152.8 29.6 6.2e-15 55.6 1.9 4.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX93441.1 - 4.1e-40 135.6 3.7 4.1e-40 135.6 3.7 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX93441.1 - 1e-31 108.0 5.5 4.9e-07 29.9 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX93441.1 - 3.6e-31 107.1 9.1 1.9e-12 47.4 0.1 7.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93441.1 - 2.1e-25 86.0 5.5 0.00013 22.2 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX93441.1 - 7e-24 83.6 13.8 6.6e-09 35.9 0.3 5.8 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Glyco_hydro_11 PF00457.17 EAX93441.1 - 0.043 13.4 0.1 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 MCC-bdg_PDZ PF10506.9 EAX93441.1 - 1.1 9.4 10.8 9.6 6.3 0.3 4.4 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2970 PF11174.8 EAX93442.1 - 0.06 13.2 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) CENP-S PF15630.6 EAX93443.1 - 9.1e-15 54.8 0.1 1.3e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAX93443.1 - 1.5e-08 34.7 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EAX93443.1 - 2.7e-05 24.1 0.3 4.1e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EAX93443.1 - 0.00026 20.9 0.1 0.00035 20.5 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated Myf5 PF12232.8 EAX93443.1 - 0.02 15.6 1.0 0.038 14.8 1.0 1.4 1 0 0 1 1 1 0 Myogenic determination factor 5 Spo12 PF05032.12 EAX93443.1 - 0.035 14.0 0.7 0.081 12.8 0.7 1.6 1 0 0 1 1 1 0 Spo12 family TFIID-31kDa PF02291.15 EAX93443.1 - 0.049 13.7 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 EAX93443.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DNA_primase_lrg PF04104.14 EAX93444.1 - 1.1e-33 116.8 3.2 1.6e-33 116.2 3.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit LRR_5 PF13306.6 EAX93445.1 - 8.2e-46 155.1 59.4 2.1e-19 69.7 18.8 3.4 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93445.1 - 9.2e-11 41.3 20.9 0.0086 15.8 6.7 4.9 2 1 1 4 4 4 4 Leucine rich repeat TSA PF03249.13 EAX93445.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen TraC_F_IV PF11130.8 EAX93446.1 - 0.034 13.7 0.5 0.29 10.7 0.3 2.5 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer EcsC PF12787.7 EAX93446.1 - 0.055 13.1 3.8 6 6.5 0.1 3.0 2 0 0 2 2 2 0 EcsC protein family DUF2205 PF10224.9 EAX93446.1 - 0.062 13.3 4.9 1.9 8.5 0.9 3.2 2 0 0 2 2 2 0 Short coiled-coil protein OmpH PF03938.14 EAX93446.1 - 0.71 10.2 10.2 0.19 12.0 2.7 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4298 PF14131.6 EAX93446.1 - 1.3 9.0 11.5 1.6 8.7 0.7 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) Mer2 PF09074.10 EAX93446.1 - 3.7 7.3 22.3 1.6 8.5 2.3 4.1 4 0 0 4 4 4 0 Mer2 PSP PF04046.16 EAX93447.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93448.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF5365 PF17326.2 EAX93449.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX93449.1 - 0.037 14.4 0.3 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF4107 PF13389.6 EAX93450.1 - 1.7e-56 190.9 1.8 2.3e-56 190.4 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX93451.1 - 2.4e-11 43.9 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX93451.1 - 0.0074 16.7 0.7 0.27 11.7 0.1 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAX93451.1 - 0.12 12.5 3.6 0.23 11.6 3.6 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain PWI PF01480.17 EAX93451.1 - 0.14 12.5 0.1 0.45 10.9 0.1 1.8 1 0 0 1 1 1 0 PWI domain Ank_5 PF13857.6 EAX93452.1 - 1.1e-21 76.5 0.0 1.2e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93452.1 - 4.5e-19 68.0 0.1 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX93452.1 - 3.8e-15 54.5 0.2 5.2e-08 32.5 0.0 2.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX93452.1 - 4e-14 53.0 0.0 7.4e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93452.1 - 7.4e-14 51.9 0.0 1.1e-11 45.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) FlxA PF14282.6 EAX93453.1 - 0.0062 16.5 2.0 0.0062 16.5 2.0 7.1 3 3 4 7 7 7 2 FlxA-like protein Herpes_BLRF2 PF05812.12 EAX93453.1 - 0.16 12.1 0.2 0.16 12.1 0.2 4.6 5 3 0 5 5 5 0 Herpesvirus BLRF2 protein DUF2721 PF11026.8 EAX93453.1 - 0.34 10.8 3.7 11 5.9 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Cob_adeno_trans PF01923.18 EAX93453.1 - 5.5 7.1 17.0 2.2 8.4 0.7 3.8 2 1 1 4 4 4 0 Cobalamin adenosyltransferase WXG100 PF06013.12 EAX93453.1 - 6 7.2 13.8 0.086 13.1 0.6 4.3 3 2 0 4 4 4 0 Proteins of 100 residues with WXG Gp_dh_C PF02800.20 EAX93454.1 - 2.8e-55 186.3 0.0 3.8e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAX93454.1 - 1.9e-28 98.8 0.1 5.4e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Hydrolase_like PF13242.6 EAX93454.1 - 0.018 15.1 0.1 0.8 9.8 0.0 2.6 3 0 0 3 3 3 0 HAD-hyrolase-like zf-CSL PF05207.13 EAX93454.1 - 0.048 13.4 0.2 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 CSL zinc finger DnaJ_C PF01556.18 EAX93455.1 - 1.2e-40 139.0 0.1 1.6e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX93455.1 - 7.8e-30 102.8 1.7 1.4e-29 102.0 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EAX93455.1 - 0.011 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Pkinase PF00069.25 EAX93456.1 - 2.1e-66 224.0 0.0 4.5e-66 222.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93456.1 - 5.3e-35 121.0 0.0 9.5e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX93456.1 - 6e-06 26.4 0.0 0.1 12.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX93456.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX93456.1 - 0.00048 19.0 2.1 0.00075 18.4 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EAX93456.1 - 0.002 17.5 0.0 0.0096 15.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX93456.1 - 0.0021 17.7 0.8 0.019 14.6 0.0 2.9 2 2 1 3 3 3 1 RIO1 family FTA2 PF13095.6 EAX93456.1 - 0.022 14.4 0.2 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CpG_bind_C PF12269.8 EAX93456.1 - 0.039 13.7 4.4 0.08 12.7 4.4 1.5 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Fer4_18 PF13746.6 EAX93456.1 - 0.081 13.1 0.2 0.24 11.6 0.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain C2 PF00168.30 EAX93457.1 - 1.7e-25 89.3 0.3 2.3e-25 88.8 0.3 1.2 1 0 0 1 1 1 1 C2 domain CUE PF02845.16 EAX93458.1 - 4.1e-13 48.8 0.0 7.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 EAX93458.1 - 0.0015 18.0 0.0 0.0037 16.8 0.0 1.7 1 0 0 1 1 1 1 DMRTA motif PP2C PF00481.21 EAX93459.1 - 0.00022 21.0 0.0 0.51 9.9 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C Peptidase_M13 PF01431.21 EAX93459.1 - 0.027 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M13 PP2C_2 PF13672.6 EAX93459.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Epimerase PF01370.21 EAX93459.1 - 0.12 11.8 0.6 9 5.7 0.1 2.6 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family KHA PF11834.8 EAX93460.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DFF-C PF09033.10 EAX93460.1 - 0.21 11.5 9.1 0.32 10.9 5.1 2.2 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain ALMT PF11744.8 EAX93460.1 - 1.4 7.7 12.3 1.7 7.4 12.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Alpha-amylase PF00128.24 EAX93461.1 - 1.2e-10 41.5 0.0 6.7e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain LRR_5 PF13306.6 EAX93464.1 - 3.3e-105 347.2 83.4 5.4e-22 78.1 7.9 7.4 1 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93464.1 - 1.6e-17 63.0 26.6 0.0091 15.7 0.1 12.5 6 5 10 17 17 17 9 Leucine rich repeat LRR_4 PF12799.7 EAX93464.1 - 0.0014 19.0 34.9 0.67 10.5 0.0 11.2 8 5 5 13 13 13 3 Leucine Rich repeats (2 copies) AP4E_app_platf PF14807.6 EAX93464.1 - 0.12 12.8 0.3 4.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform Pentapeptide_3 PF13576.6 EAX93464.1 - 0.4 10.9 14.1 7.8 6.7 0.3 6.4 6 0 0 6 6 6 0 Pentapeptide repeats (9 copies) PSP PF04046.16 EAX93465.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93466.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93467.1 - 0.034 14.6 0.7 0.071 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX93468.1 - 6.2e-39 131.9 16.4 2.8e-23 81.8 6.9 5.3 7 1 0 7 7 7 2 Phage tail repeat like DUF240 PF03086.14 EAX93468.1 - 0.15 12.0 6.1 1.6 8.7 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF240) DUF3839 PF12943.7 EAX93469.1 - 4.6e-157 520.7 12.5 5.6e-157 520.4 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX93469.1 - 0.088 13.2 0.3 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX93469.1 - 0.24 11.9 7.6 2.3 8.8 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX93469.1 - 6.8 7.1 7.6 13 6.1 0.1 3.6 3 2 2 5 5 5 0 Tup N-terminal DUF4106 PF13388.6 EAX93470.1 - 4.1e-186 619.2 18.0 4.1e-186 619.2 18.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX93470.1 - 0.049 13.9 2.8 0.87 9.9 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated Gallidermin PF02052.15 EAX93471.1 - 0.23 11.8 1.3 6.1 7.3 0.1 2.3 1 1 1 2 2 2 0 Gallidermin Tub PF01167.18 EAX93473.1 - 0.0018 18.1 0.1 0.29 10.9 0.0 2.5 1 1 1 2 2 2 2 Tub family LOR PF04525.12 EAX93473.1 - 0.06 12.9 1.2 1.7 8.2 0.0 2.5 2 1 0 2 2 2 0 LURP-one-related DUF3320 PF11784.8 EAX93474.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Acetyltransf_11 PF13720.6 EAX93475.1 - 0.14 12.6 1.4 0.35 11.4 1.4 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1843 PF08898.10 EAX93476.1 - 0.0099 16.4 39.2 0.064 13.8 1.6 7.1 1 1 6 7 7 7 6 Domain of unknown function (DUF1843) Il2rg PF15874.5 EAX93476.1 - 0.019 15.2 10.6 13 6.1 0.1 4.6 1 1 3 5 5 5 0 Putative Interleukin 2 receptor, gamma chain KIF1B PF12423.8 EAX93476.1 - 7.1 7.2 18.8 33 5.0 0.2 5.8 3 2 3 6 6 6 0 Kinesin protein 1B FCSD-flav_bind PF09242.11 EAX93476.1 - 7.5 7.0 22.3 17 5.8 0.7 5.0 1 1 6 7 7 7 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding YccF PF03733.13 EAX93477.1 - 1.8e-12 47.8 12.4 1.8e-12 47.8 12.4 5.4 6 1 1 7 7 7 1 Inner membrane component domain Na_Ca_ex PF01699.24 EAX93477.1 - 1.1e-11 44.9 44.0 4.9e-07 29.8 17.5 3.6 3 2 0 3 3 3 2 Sodium/calcium exchanger protein DUF5527 PF17665.1 EAX93477.1 - 1.3 8.6 4.2 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Sugar_tr PF00083.24 EAX93478.1 - 4.1e-54 184.1 34.2 5.6e-52 177.1 34.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX93478.1 - 8.7e-26 90.7 36.7 4.3e-14 52.2 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX93478.1 - 2.6e-08 32.9 27.6 0.0007 18.3 5.6 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein Sigma_reg_N PF13800.6 EAX93478.1 - 2.8 8.3 0.0 2.8 8.3 0.0 3.2 4 0 0 4 4 4 0 Sigma factor regulator N-terminal HSP70 PF00012.20 EAX93479.1 - 2.4e-27 95.4 0.0 2.4e-27 95.4 0.0 3.4 3 1 0 3 3 3 2 Hsp70 protein FtsA PF14450.6 EAX93479.1 - 0.0021 18.4 0.0 0.019 15.4 0.0 2.5 3 0 0 3 3 3 1 Cell division protein FtsA MutL PF13941.6 EAX93479.1 - 0.034 12.7 0.0 5.6 5.5 0.0 2.2 2 0 0 2 2 2 0 MutL protein YtxH PF12732.7 EAX93479.1 - 0.099 13.2 0.5 0.98 10.0 0.4 2.8 2 1 0 2 2 2 0 YtxH-like protein AAA_22 PF13401.6 EAX93480.1 - 0.00014 22.1 0.0 0.18 12.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAX93480.1 - 0.00024 20.8 0.1 0.26 11.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EAX93480.1 - 0.014 14.7 0.0 4.2 6.7 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family IcmF-related PF06761.12 EAX93480.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing AAA_14 PF13173.6 EAX93480.1 - 0.071 13.2 0.6 5.1 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.21 EAX93480.1 - 0.097 12.7 0.2 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 MutS domain V SPATA6 PF14909.6 EAX93480.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 ORC6 PF05460.13 EAX93480.1 - 0.14 11.4 8.4 0.29 10.3 8.4 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ank_2 PF12796.7 EAX93481.1 - 4.8e-58 193.7 11.1 1.2e-17 64.2 0.1 4.9 2 1 4 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93481.1 - 1.5e-42 143.4 1.7 4.1e-09 36.8 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93481.1 - 2.5e-38 129.6 1.5 9.3e-06 25.8 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX93481.1 - 5.6e-32 108.8 0.3 0.0015 18.9 0.0 9.3 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 EAX93481.1 - 4.6e-29 97.2 2.1 0.012 16.0 0.0 9.4 10 0 0 10 10 8 6 Ankyrin repeat EzrA PF06160.12 EAX93481.1 - 3.4e-06 25.6 14.1 5.3e-06 24.9 14.1 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA ATG16 PF08614.11 EAX93481.1 - 1.1e-05 25.8 6.2 2.1e-05 24.8 6.2 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAX93481.1 - 1.5e-05 24.1 8.1 3e-05 23.1 8.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein HAUS5 PF14817.6 EAX93481.1 - 3.7e-05 22.7 3.4 5.3e-05 22.2 3.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 APG6_N PF17675.1 EAX93481.1 - 4.8e-05 23.9 12.2 6.6e-05 23.5 10.5 2.0 1 1 1 2 2 1 1 Apg6 coiled-coil region zf-C4H2 PF10146.9 EAX93481.1 - 5.4e-05 23.6 7.7 0.00011 22.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein DUF812 PF05667.11 EAX93481.1 - 7.8e-05 21.8 6.2 0.00013 21.0 6.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) BRE1 PF08647.11 EAX93481.1 - 0.0001 22.3 14.3 0.0001 22.3 14.3 1.8 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 EAX93481.1 - 0.00013 22.5 7.8 0.00013 22.5 7.8 1.6 2 0 0 2 2 1 1 Fez1 CENP-F_leu_zip PF10473.9 EAX93481.1 - 0.00014 21.9 9.5 0.00027 21.0 9.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 EAX93481.1 - 0.00023 21.5 5.0 0.00057 20.2 5.0 1.7 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) GAS PF13851.6 EAX93481.1 - 0.00044 19.7 12.5 0.00096 18.6 12.5 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EAX93481.1 - 0.0011 16.7 5.9 0.0015 16.2 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 EAX93481.1 - 0.0014 17.8 10.3 0.0022 17.1 10.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 EAX93481.1 - 0.0014 18.9 17.6 0.0059 16.9 1.7 3.9 2 1 2 4 4 3 2 TSC-22/dip/bun family LPP PF04728.13 EAX93481.1 - 0.0015 18.9 9.1 0.014 15.8 1.3 3.5 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Paramyx_P_V_C PF03210.13 EAX93481.1 - 0.0016 18.3 0.5 0.31 10.8 0.4 3.0 2 1 1 3 3 3 1 Paramyxovirus P/V phosphoprotein C-terminal DUF1664 PF07889.12 EAX93481.1 - 0.0021 18.1 4.7 0.0044 17.0 4.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EAX93481.1 - 0.0021 18.2 15.6 0.003 17.7 14.1 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EAX93481.1 - 0.0025 18.5 10.9 0.0096 16.6 10.9 2.0 1 0 0 1 1 1 1 Occludin homology domain Laminin_I PF06008.14 EAX93481.1 - 0.0031 17.3 11.3 0.0062 16.3 11.3 1.4 1 0 0 1 1 1 1 Laminin Domain I ADIP PF11559.8 EAX93481.1 - 0.0031 17.6 10.7 0.0031 17.6 10.7 2.8 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EAX93481.1 - 0.0036 17.1 11.3 0.0049 16.7 9.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF724) HMMR_N PF15905.5 EAX93481.1 - 0.0037 16.8 12.3 0.0071 15.9 12.3 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF4472 PF14739.6 EAX93481.1 - 0.0055 17.4 8.4 0.009 16.7 6.6 2.5 2 0 0 2 2 1 1 Domain of unknown function (DUF4472) DUF3450 PF11932.8 EAX93481.1 - 0.0058 16.0 7.8 0.011 15.0 7.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EAX93481.1 - 0.0061 16.6 2.9 0.0061 16.6 2.9 3.5 3 1 1 4 4 2 2 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 EAX93481.1 - 0.0064 16.7 7.4 0.014 15.6 7.4 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EAX93481.1 - 0.0068 15.9 7.3 0.012 15.2 7.3 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 T3SSipB PF16535.5 EAX93481.1 - 0.011 16.2 2.4 0.021 15.3 2.4 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 EAX93481.1 - 0.011 15.7 9.9 0.011 15.7 9.9 1.8 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EAX93481.1 - 0.013 15.1 3.8 0.018 14.6 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mit_ribos_Mrp51 PF11709.8 EAX93481.1 - 0.02 14.5 3.0 0.03 13.9 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit TMF_TATA_bd PF12325.8 EAX93481.1 - 0.033 14.4 12.6 0.025 14.8 8.9 2.5 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAX93481.1 - 0.035 13.5 4.0 0.056 12.8 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3287 PF11690.8 EAX93481.1 - 0.04 13.6 0.3 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Pox_A_type_inc PF04508.12 EAX93481.1 - 0.046 13.6 0.7 3.5 7.6 0.1 3.7 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat Spectrin PF00435.21 EAX93481.1 - 0.061 13.8 2.6 0.14 12.7 1.3 2.3 1 1 1 2 2 2 0 Spectrin repeat HemX PF04375.14 EAX93481.1 - 0.063 12.6 7.1 0.03 13.6 4.3 1.7 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Complex1_LYR_2 PF13233.6 EAX93481.1 - 0.073 13.8 2.8 2.1 9.2 3.0 3.2 3 0 0 3 3 1 0 Complex1_LYR-like KASH_CCD PF14662.6 EAX93481.1 - 0.079 12.8 18.9 0.015 15.2 14.8 1.9 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH Fungal_TACC PF12709.7 EAX93481.1 - 0.083 13.3 16.6 0.58 10.6 3.4 3.6 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 EAX93481.1 - 0.084 12.7 19.0 0.2 11.5 4.2 3.4 2 1 1 3 3 2 0 Septum formation initiator YlqD PF11068.8 EAX93481.1 - 0.09 13.2 8.5 0.19 12.1 8.5 1.6 1 0 0 1 1 1 0 YlqD protein DHR10 PF18595.1 EAX93481.1 - 0.1 12.7 8.8 0.23 11.5 4.2 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CREPT PF16566.5 EAX93481.1 - 0.11 12.7 8.5 0.34 11.1 1.9 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 EAX93481.1 - 0.14 12.6 21.8 0.074 13.5 6.9 3.1 2 1 1 3 3 2 0 Cell division protein ZapB USP8_interact PF08941.10 EAX93481.1 - 0.15 11.8 2.7 0.3 10.9 1.4 2.1 2 0 0 2 2 1 0 USP8 interacting CALCOCO1 PF07888.11 EAX93481.1 - 0.16 10.8 6.9 0.68 8.7 6.2 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SKA2 PF16740.5 EAX93481.1 - 0.16 11.7 6.5 1 9.2 0.5 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 PspA_IM30 PF04012.12 EAX93481.1 - 0.18 11.4 3.9 0.14 11.7 1.6 1.8 1 1 1 2 2 2 0 PspA/IM30 family Yuri_gagarin PF15934.5 EAX93481.1 - 0.18 11.6 16.5 0.26 11.1 13.7 2.2 1 1 1 2 2 2 0 Yuri gagarin CENP-H PF05837.12 EAX93481.1 - 0.19 12.1 9.1 0.71 10.3 1.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) JIP_LZII PF16471.5 EAX93481.1 - 0.29 11.4 4.6 8 6.7 0.8 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 EAX93481.1 - 0.34 10.1 11.1 0.86 8.8 11.0 1.8 1 1 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 EAX93481.1 - 0.35 11.2 5.0 0.52 10.6 3.5 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Med9 PF07544.13 EAX93481.1 - 0.36 10.9 8.0 0.13 12.4 1.4 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 EAX93481.1 - 0.39 11.1 14.1 3 8.3 2.2 3.7 1 1 2 3 3 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 EAX93481.1 - 0.46 10.6 19.3 0.19 11.9 3.8 3.1 2 1 1 3 3 3 0 Tropomyosin like Cnn_1N PF07989.11 EAX93481.1 - 0.49 10.6 13.3 0.53 10.5 10.7 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 EAX93481.1 - 0.51 10.8 3.0 3.5 8.1 0.4 2.6 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.6 EAX93481.1 - 0.51 10.8 19.7 0.04 14.3 4.9 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) CLZ PF16526.5 EAX93481.1 - 0.55 10.6 3.5 5.1 7.5 0.7 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels She9_MDM33 PF05546.11 EAX93481.1 - 0.84 9.4 9.8 0.15 11.8 5.7 1.8 2 0 0 2 2 1 0 She9 / Mdm33 family GIT_CC PF16559.5 EAX93481.1 - 0.89 9.5 11.6 0.055 13.3 3.3 2.8 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 EAX93481.1 - 1.1 9.6 20.6 1.1 9.7 3.3 4.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uds1 PF15456.6 EAX93481.1 - 1.2 9.3 5.1 5.1 7.3 0.4 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Nup54 PF13874.6 EAX93481.1 - 1.2 9.2 5.1 5.9 7.0 5.1 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 THOC7 PF05615.13 EAX93481.1 - 1.3 9.3 10.4 0.13 12.6 5.2 2.1 2 0 0 2 2 1 0 Tho complex subunit 7 DUF2203 PF09969.9 EAX93481.1 - 1.3 9.7 6.1 1 10.1 3.5 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) MscS_porin PF12795.7 EAX93481.1 - 1.4 8.4 13.7 0.069 12.7 7.5 1.8 2 0 0 2 2 1 0 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.20 EAX93481.1 - 1.5 8.8 13.2 5.6 7.0 2.2 2.8 1 1 1 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EAX93481.1 - 1.7 8.7 10.2 5 7.2 9.9 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CC2-LZ PF16516.5 EAX93481.1 - 1.8 9.0 10.7 5 7.6 2.7 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4201 PF13870.6 EAX93481.1 - 2.4 7.8 20.0 0.41 10.4 14.9 2.3 2 1 0 2 2 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 EAX93481.1 - 2.6 8.6 7.0 1.5e+02 3.0 7.0 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 EAX93481.1 - 2.6 8.5 12.5 1.8 9.0 5.5 3.1 1 1 2 3 3 3 0 Snapin/Pallidin TolA_bind_tri PF16331.5 EAX93481.1 - 2.7 8.2 7.3 2.7 8.1 3.4 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation FliJ PF02050.16 EAX93481.1 - 2.7 8.2 12.8 1 9.6 9.0 2.2 2 1 0 2 2 1 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.22 EAX93481.1 - 3 8.1 18.9 0.097 12.9 8.7 3.1 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF1640 PF07798.11 EAX93481.1 - 3.2 7.8 11.8 15 5.6 11.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Noelin-1 PF12308.8 EAX93481.1 - 3.5 7.7 6.6 5.9 6.9 2.2 2.9 2 1 1 3 3 3 0 Neurogenesis glycoprotein LMBR1 PF04791.16 EAX93481.1 - 3.6 6.4 8.1 5.5 5.8 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CorA PF01544.18 EAX93481.1 - 3.9 6.7 8.8 12 5.1 8.2 1.9 1 1 0 2 2 1 0 CorA-like Mg2+ transporter protein Fzo_mitofusin PF04799.13 EAX93481.1 - 4.5 6.8 8.1 6.5 6.3 3.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region Tup_N PF08581.10 EAX93481.1 - 5.3 7.4 16.0 1.7 9.0 4.3 3.2 2 1 2 4 4 3 0 Tup N-terminal IFT20 PF14931.6 EAX93481.1 - 5.4 7.2 14.4 1.4 9.1 10.3 2.1 2 0 0 2 2 1 0 Intraflagellar transport complex B, subunit 20 Uso1_p115_C PF04871.13 EAX93481.1 - 6.2 7.2 16.9 1.2 9.5 11.8 2.4 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 EAX93481.1 - 6.4 7.4 14.7 0.32 11.6 1.5 3.2 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 EAX93481.1 - 7.7 7.2 15.7 9.4 6.9 11.5 2.9 2 1 0 2 2 1 0 Initiation control protein YabA LOH1CR12 PF10158.9 EAX93481.1 - 8.1 6.5 8.2 21 5.1 6.5 2.3 1 1 1 2 2 2 0 Tumour suppressor protein PI_PP_I PF18363.1 EAX93481.1 - 8.1 6.7 8.6 15 5.8 6.0 2.7 2 1 0 2 2 1 0 Phosphoinositide phosphatase insertion domain DUF4094 PF13334.6 EAX93481.1 - 8.7 6.8 10.3 0.99 9.9 1.9 3.5 3 1 1 4 4 2 0 Domain of unknown function (DUF4094) SHIPPO-rpt PF07004.12 EAX93482.1 - 5.4e-07 30.2 17.5 0.02 15.8 2.5 4.4 3 2 0 3 3 3 3 Sperm-tail PG-rich repeat Methyltransf_11 PF08241.12 EAX93483.1 - 9.2e-15 55.1 0.1 1.6e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX93483.1 - 1.5e-12 48.0 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX93483.1 - 1.2e-11 44.7 0.1 1.7e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX93483.1 - 0.00013 22.6 0.0 0.00022 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAX93483.1 - 0.00049 19.6 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAX93483.1 - 0.0015 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EAX93483.1 - 0.0052 16.4 0.0 0.007 16.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EAX93483.1 - 0.008 15.4 0.3 0.088 12.0 0.0 2.1 1 1 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_PK PF05891.12 EAX93483.1 - 0.01 15.4 0.5 0.027 14.0 0.5 1.6 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CAP_N PF01213.19 EAX93483.1 - 0.82 9.1 7.2 2.6 7.5 5.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Peptidase_C1 PF00112.23 EAX93484.1 - 1.2e-10 41.9 4.8 1.5e-10 41.5 3.9 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX93484.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 EAX93485.1 - 1.9e-40 139.3 0.6 2e-40 139.2 0.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX93485.1 - 0.00077 18.4 0.1 0.001 17.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF4106 PF13388.6 EAX93486.1 - 1.3e-275 914.1 23.7 1.3e-275 914.1 23.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3447 PF11929.8 EAX93487.1 - 2.2e-35 120.4 5.9 2.2e-35 120.4 5.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93487.1 - 2.6e-27 95.2 7.8 4.2e-15 56.1 2.4 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93487.1 - 6.4e-26 89.6 6.0 3.4e-07 30.4 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX93487.1 - 1.7e-24 85.8 8.4 3.7e-09 36.9 0.3 6.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93487.1 - 1.7e-22 79.2 14.1 6.1e-09 36.0 0.6 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93487.1 - 7.2e-17 59.8 10.7 0.00046 20.4 0.0 6.5 8 0 0 8 8 8 4 Ankyrin repeat SWIRM PF04433.17 EAX93487.1 - 0.013 15.8 0.6 0.042 14.2 0.6 1.8 1 0 0 1 1 1 0 SWIRM domain WPP PF13943.6 EAX93487.1 - 0.078 13.4 0.3 20 5.6 0.0 2.6 1 1 2 3 3 3 0 WPP domain Ras PF00071.22 EAX93488.1 - 5e-09 36.0 0.0 9.3e-09 35.1 0.0 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EAX93488.1 - 2.2e-08 34.3 0.0 4.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX93488.1 - 0.00037 20.0 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX93488.1 - 0.001 18.5 0.8 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX93488.1 - 0.0027 17.0 0.2 0.29 10.2 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit DLIC PF05783.11 EAX93488.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 EAX93488.1 - 0.034 14.2 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MaoC_dehydratas PF01575.19 EAX93488.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 MaoC like domain FtsK_SpoIIIE PF01580.18 EAX93488.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EAX93488.1 - 0.087 12.9 0.6 0.37 10.8 0.1 2.2 2 1 1 3 3 3 0 Dynamin family CorA PF01544.18 EAX93489.1 - 0.037 13.3 4.2 0.04 13.2 1.4 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2286 PF10051.9 EAX93490.1 - 0.032 14.0 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) IBN_N PF03810.19 EAX93490.1 - 0.09 12.7 5.0 26 4.8 0.0 4.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain ZapB PF06005.12 EAX93491.1 - 0.018 15.5 0.7 0.027 14.9 0.7 1.3 1 0 0 1 1 1 0 Cell division protein ZapB HCR PF07111.12 EAX93491.1 - 0.018 13.2 0.1 0.021 13.0 0.1 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) bZIP_1 PF00170.21 EAX93491.1 - 0.031 14.4 1.6 0.051 13.7 0.8 1.7 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EAX93491.1 - 0.05 13.4 0.5 0.69 9.7 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.12 EAX93491.1 - 0.053 13.4 1.7 2.4 8.2 0.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3450 PF11932.8 EAX93491.1 - 0.074 12.3 0.7 0.088 12.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.15 EAX93491.1 - 0.19 11.8 3.6 0.29 11.3 0.8 2.0 1 1 1 2 2 2 0 Basic region leucine zipper DUF2012 PF09430.10 EAX93492.1 - 0.0097 16.0 0.3 0.049 13.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) HTH_22 PF13309.6 EAX93493.1 - 0.017 15.1 0.1 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 HTH domain PHD PF00628.29 EAX93494.1 - 3.5e-11 42.8 21.0 1.6e-06 27.9 10.4 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EAX93494.1 - 0.00011 21.7 16.9 0.016 14.8 1.9 2.5 2 0 0 2 2 2 2 PHD-finger B3 PF02362.21 EAX93494.1 - 0.13 12.1 0.1 2.6 8.0 0.0 3.0 4 0 0 4 4 4 0 B3 DNA binding domain PHD_3 PF13922.6 EAX93494.1 - 1 9.8 13.4 0.25 11.7 0.4 3.6 4 0 0 4 4 4 0 PHD domain of transcriptional enhancer, Asx GAGA_bind PF06217.12 EAX93494.1 - 3 8.1 18.5 17 5.6 0.1 2.8 2 0 0 2 2 2 0 GAGA binding protein-like family UNC45-central PF11701.8 EAX93495.1 - 0.0059 16.6 6.1 0.93 9.4 0.0 4.6 3 1 2 6 6 6 2 Myosin-binding striated muscle assembly central DDOST_48kD PF03345.14 EAX93495.1 - 0.0088 14.9 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta UME PF08064.13 EAX93495.1 - 0.083 12.8 0.1 1.1 9.2 0.1 3.0 1 1 0 1 1 1 0 UME (NUC010) domain Tudor_FRX1 PF18336.1 EAX93496.1 - 0.003 17.4 0.5 1.2 9.1 0.0 3.0 2 0 0 2 2 2 2 Fragile X mental retardation Tudor domain Peptidase_M8 PF01457.16 EAX93497.1 - 1.3e-14 53.8 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.24 EAX93497.1 - 2.6e-06 27.4 0.1 7.8e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain DDR PF08841.10 EAX93498.1 - 0.18 10.8 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Metallophos PF00149.28 EAX93499.1 - 2.3e-30 106.6 0.1 3.4e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ARL2_Bind_BART PF11527.8 EAX93500.1 - 0.029 14.5 0.5 0.034 14.2 0.5 1.1 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Glyoxalase_2 PF12681.7 EAX93500.1 - 0.043 13.7 0.2 0.043 13.7 0.2 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain MscS_porin PF12795.7 EAX93502.1 - 0.0017 17.9 4.0 0.28 10.7 0.3 2.1 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 EAX93502.1 - 0.0018 18.5 5.0 0.027 14.7 0.4 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EAX93502.1 - 0.0027 16.9 8.6 0.0033 16.6 8.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EAX93502.1 - 0.0044 17.5 3.7 0.051 14.1 0.1 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region DivIC PF04977.15 EAX93502.1 - 0.0047 16.7 0.6 0.0047 16.7 0.6 2.3 2 0 0 2 2 2 1 Septum formation initiator DUF4482 PF14818.6 EAX93502.1 - 0.0049 17.7 5.9 0.036 14.9 0.5 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4482) Tektin PF03148.14 EAX93502.1 - 0.011 14.5 3.1 0.011 14.5 3.1 1.7 1 1 0 1 1 1 0 Tektin family MIP-T3_C PF17749.1 EAX93502.1 - 0.013 15.5 1.9 0.8 9.7 0.3 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fez1 PF06818.15 EAX93502.1 - 0.016 15.7 3.6 0.019 15.4 3.6 1.1 1 0 0 1 1 1 0 Fez1 DUF4140 PF13600.6 EAX93502.1 - 0.018 15.5 2.6 0.28 11.7 0.3 2.5 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5082 PF16888.5 EAX93502.1 - 0.018 15.3 4.2 0.073 13.3 4.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Hrs_helical PF12210.8 EAX93502.1 - 0.02 15.4 0.8 0.49 11.0 0.1 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TMF_DNA_bd PF12329.8 EAX93502.1 - 0.025 14.6 3.0 0.025 14.6 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EAX93502.1 - 0.03 14.9 1.1 0.1 13.2 0.3 2.0 2 0 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 EAX93502.1 - 0.03 14.6 5.7 0.071 13.4 1.7 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 EAX93502.1 - 0.032 14.5 1.5 0.32 11.3 1.5 2.4 1 1 0 1 1 1 0 TSC-22/dip/bun family Prefoldin_2 PF01920.20 EAX93502.1 - 0.04 13.9 6.6 0.41 10.6 1.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 EAX93502.1 - 0.041 13.2 0.3 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HlyD_2 PF12700.7 EAX93502.1 - 0.067 11.9 3.1 0.089 11.5 3.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein CC2-LZ PF16516.5 EAX93502.1 - 0.069 13.5 3.2 0.24 11.8 0.2 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator COMP PF11598.8 EAX93502.1 - 0.08 13.4 0.9 0.17 12.4 0.9 1.6 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein V_ATPase_I PF01496.19 EAX93502.1 - 0.082 10.8 1.7 0.11 10.4 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EAX93502.1 - 0.088 13.5 2.1 0.25 12.0 2.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA FlxA PF14282.6 EAX93502.1 - 0.089 12.8 10.5 0.51 10.4 1.6 3.1 2 1 1 3 3 3 0 FlxA-like protein XhlA PF10779.9 EAX93502.1 - 0.11 12.7 5.9 0.11 12.8 2.4 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DMPK_coil PF08826.10 EAX93502.1 - 0.16 12.1 3.4 0.19 11.9 1.4 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like GrpE PF01025.19 EAX93502.1 - 0.22 11.1 5.8 0.69 9.5 0.4 2.2 1 1 1 2 2 2 0 GrpE TolA_bind_tri PF16331.5 EAX93502.1 - 0.29 11.3 6.8 0.11 12.6 2.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation BST2 PF16716.5 EAX93502.1 - 0.3 11.7 4.3 0.3 11.7 0.8 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Prefoldin PF02996.17 EAX93502.1 - 0.42 10.5 6.0 0.64 9.9 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit Sec2p PF06428.11 EAX93502.1 - 0.43 10.6 4.6 2.5 8.1 0.7 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PRKG1_interact PF15898.5 EAX93502.1 - 0.5 11.3 8.0 0.75 10.7 0.5 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4404 PF14357.6 EAX93502.1 - 0.65 10.7 4.4 1.3 9.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) FlaC_arch PF05377.11 EAX93502.1 - 0.72 10.3 6.4 1 9.8 2.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 EAX93502.1 - 0.75 9.9 9.3 0.077 13.1 2.3 2.4 2 1 0 2 2 2 0 Hr1 repeat DUF5320 PF17253.2 EAX93502.1 - 0.77 10.9 2.2 39 5.4 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) AATF-Che1 PF13339.6 EAX93502.1 - 2.1 9.0 7.7 6.9 7.4 5.8 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor FapA PF03961.13 EAX93502.1 - 2.7 6.5 5.8 7.6 5.0 5.8 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Cep57_CLD_2 PF14197.6 EAX93502.1 - 7.7 6.7 9.8 3 8.0 4.6 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DnaGprimase_HBD PF16730.5 EAX93503.1 - 0.024 14.7 2.0 0.47 10.5 0.1 2.6 3 0 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain SOAR PF16533.5 EAX93503.1 - 2.5 8.1 7.0 1.5 8.8 1.5 2.9 1 1 0 2 2 2 0 STIM1 Orai1-activating region Lactamase_B PF00753.27 EAX93504.1 - 1e-20 74.6 0.1 2.4e-20 73.4 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAX93504.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAX93504.1 - 0.0085 16.0 0.2 0.029 14.3 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4336 PF14234.6 EAX93504.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Cation_efflux PF01545.21 EAX93505.1 - 1.3e-47 162.1 11.3 1.7e-47 161.7 11.3 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EAX93505.1 - 0.83 8.8 26.4 0.2 10.9 7.9 2.9 3 0 0 3 3 3 0 ZIP Zinc transporter NanE PF04131.14 EAX93507.1 - 0.015 14.5 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF4634 PF15465.6 EAX93507.1 - 0.11 12.8 0.6 0.36 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) ubiquitin PF00240.23 EAX93508.1 - 8.5e-10 38.3 0.1 2e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EAX93508.1 - 7.5e-06 25.7 0.1 1.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 EAX93508.1 - 0.00083 19.0 1.8 0.7 9.7 0.2 2.9 3 0 0 3 3 3 2 CUE domain UBA_4 PF14555.6 EAX93508.1 - 0.00089 19.0 0.7 0.97 9.3 0.1 2.6 2 1 0 2 2 2 2 UBA-like domain WIYLD PF10440.9 EAX93508.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Rad60-SLD PF11976.8 EAX93508.1 - 0.03 14.1 0.2 0.073 12.9 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SH3_2 PF07653.17 EAX93508.1 - 0.099 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Beta_helix PF13229.6 EAX93509.1 - 0.00015 21.7 14.9 0.00023 21.0 14.9 1.4 1 1 0 1 1 1 1 Right handed beta helix region Ago_N_1 PF18351.1 EAX93510.1 - 0.74 10.3 5.6 2.6 8.5 0.1 3.9 3 0 0 3 3 3 0 Fungal Argonaute N-terminal domain Beta_helix PF13229.6 EAX93511.1 - 9.5e-06 25.5 12.9 1.4e-05 25.0 12.9 1.2 1 0 0 1 1 1 1 Right handed beta helix region Arginase PF00491.21 EAX93512.1 - 6.1e-25 88.3 0.0 7.7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family Churchill PF06573.11 EAX93512.1 - 0.041 14.2 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Churchill protein RecG_wedge PF17191.4 EAX93512.1 - 0.068 12.8 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 RecG wedge domain UCH PF00443.29 EAX93513.1 - 2e-17 63.5 0.4 2e-17 63.5 0.4 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAX93513.1 - 2.4e-09 36.9 3.8 0.00027 20.3 0.4 2.6 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 DUF4366 PF14283.6 EAX93514.1 - 0.0015 18.6 0.3 0.0015 18.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Orf78 PF06024.12 EAX93514.1 - 0.061 13.6 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) PKI PF02827.16 EAX93514.1 - 2.3 8.5 6.6 0.24 11.6 1.2 1.8 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor C2 PF00168.30 EAX93515.1 - 2.2e-10 40.7 0.1 2.7e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 C2 domain Rootletin PF15035.6 EAX93516.1 - 0.32 11.0 4.4 0.35 10.9 1.7 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Pkinase_Tyr PF07714.17 EAX93517.1 - 9.5e-09 34.9 0.0 6.1e-07 29.0 0.0 3.1 2 1 1 3 3 3 1 Protein tyrosine kinase Ank_4 PF13637.6 EAX93517.1 - 1.2e-07 32.1 0.0 8.6e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93517.1 - 2.7e-07 31.1 0.0 1.5e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 EAX93517.1 - 5.2e-07 29.3 0.1 0.0037 16.7 0.0 3.3 2 2 1 3 3 3 2 Protein kinase domain Ank PF00023.30 EAX93517.1 - 1.1e-06 28.8 0.1 0.028 14.9 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX93517.1 - 1.6e-05 24.9 0.2 0.13 12.9 0.1 3.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX93517.1 - 0.00079 19.7 0.1 0.003 17.8 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ABC_tran PF00005.27 EAX93518.1 - 5.2e-09 36.7 0.3 2.5e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAX93518.1 - 0.14 11.6 0.4 0.28 10.6 0.1 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain HALZ PF02183.18 EAX93520.1 - 0.011 15.9 8.1 0.23 11.7 0.8 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper SCIMP PF15050.6 EAX93520.1 - 0.016 15.7 2.5 0.016 15.7 2.5 4.2 2 1 1 3 3 3 0 SCIMP protein Snf7 PF03357.21 EAX93521.1 - 1.8e-11 43.9 17.4 2.9e-11 43.2 17.4 1.3 1 1 0 1 1 1 1 Snf7 DUF386 PF04074.12 EAX93521.1 - 0.0097 15.8 0.1 0.014 15.3 0.1 1.4 1 1 0 1 1 1 1 YhcH/YjgK/YiaL DUF4824 PF16106.5 EAX93521.1 - 0.049 12.9 3.7 0.061 12.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) DUF5471 PF17565.2 EAX93521.1 - 0.2 12.0 5.5 0.1 12.9 3.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5471) Pkinase PF00069.25 EAX93522.1 - 9.7e-10 38.2 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93522.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase GPS2_interact PF15784.5 EAX93524.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93524.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX93525.1 - 0.021 14.8 5.9 0.033 14.2 5.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX93526.1 - 0.023 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX93527.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX93527.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ste5_C PF12194.8 EAX93528.1 - 0.053 13.5 0.7 9.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase Fus3-binding Amidase02_C PF12123.8 EAX93531.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX93532.1 - 3.4e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX93532.1 - 0.12 10.8 1.0 0.17 10.3 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase SIS PF01380.22 EAX93534.1 - 7.9e-50 168.1 0.1 5.6e-26 90.9 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EAX93534.1 - 6e-14 52.4 0.2 2e-11 44.2 0.2 2.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EAX93534.1 - 1.6e-06 28.1 0.1 0.00033 20.5 0.0 3.1 2 1 1 3 3 3 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAX93534.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 EAX93534.1 - 0.038 12.7 0.1 0.33 9.6 0.1 2.0 1 1 1 2 2 2 0 Glutamine amidotransferases class-II Hydrolase_4 PF12146.8 EAX93535.1 - 9.3e-21 74.2 0.0 4.7e-13 49.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX93535.1 - 7.2e-14 52.0 0.2 1.1e-10 41.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EAX93535.1 - 1.2e-10 41.5 0.0 2e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EAX93535.1 - 2.8e-06 28.1 0.0 3.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EAX93535.1 - 2.2e-05 24.2 0.0 4.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 EAX93535.1 - 0.00049 19.8 0.2 0.0026 17.5 0.3 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EAX93535.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EAX93535.1 - 0.0054 16.7 0.1 0.024 14.6 0.1 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EAX93535.1 - 0.016 13.9 0.0 0.033 12.9 0.0 1.5 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) DUF915 PF06028.11 EAX93535.1 - 0.017 14.5 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PhoPQ_related PF10142.9 EAX93535.1 - 0.13 10.9 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein TMEM154 PF15102.6 EAX93539.1 - 6.5e-05 22.9 0.4 0.00011 22.1 0.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EAX93539.1 - 0.00042 20.2 0.2 0.00078 19.3 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EAX93539.1 - 0.0008 19.6 0.2 0.0012 18.9 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX93539.1 - 0.0021 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) T4SS_CagC PF16943.5 EAX93539.1 - 0.027 14.7 0.6 0.051 13.8 0.6 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF5305 PF17231.2 EAX93539.1 - 0.041 13.3 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Insulin_TMD PF17870.1 EAX93539.1 - 0.099 12.7 4.9 0.24 11.5 4.9 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RhoGAP PF00620.27 EAX93540.1 - 1.5e-16 60.6 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EAX93540.1 - 1.5e-09 38.3 0.1 3.1e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 MyTH4 domain FOP_dimer PF09398.10 EAX93540.1 - 0.16 12.2 0.9 10 6.5 0.0 3.2 4 0 0 4 4 4 0 FOP N terminal dimerisation domain Cyt-b5 PF00173.28 EAX93542.1 - 1.1e-19 70.3 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_31 PF01055.26 EAX93543.1 - 6.9e-124 414.4 1.5 1e-123 413.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAX93543.1 - 1.8e-17 63.4 2.4 1.7e-15 57.1 0.1 3.3 3 0 0 3 3 3 2 Galactose mutarotase-like DUF5110 PF17137.4 EAX93543.1 - 0.00038 20.7 0.2 0.0012 19.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Pkinase PF00069.25 EAX93544.1 - 1e-17 64.4 0.0 1.1e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93544.1 - 6.5e-06 25.6 0.0 7.5e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93544.1 - 0.0053 16.1 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SpoU_sub_bind PF08032.12 EAX93545.1 - 0.09 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding VPS9 PF02204.18 EAX93546.1 - 0.00022 21.4 0.0 0.00074 19.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF3800 PF12686.7 EAX93548.1 - 0.025 15.2 0.1 0.66 10.6 0.1 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Put_DNA-bind_N PF06971.13 EAX93548.1 - 0.15 12.1 2.0 1.1 9.3 0.2 3.2 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus WXG100 PF06013.12 EAX93548.1 - 5 7.4 12.8 9.5 6.5 0.0 5.7 6 1 0 6 6 6 0 Proteins of 100 residues with WXG TACC_C PF05010.14 EAX93548.1 - 5.2 6.8 34.5 0.054 13.3 11.7 3.1 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KxDL PF10241.9 EAX93548.1 - 6.1 7.2 27.2 4.2 7.7 0.1 5.9 3 2 2 6 6 6 0 Uncharacterized conserved protein AvrLm4-7 PF18661.1 EAX93548.1 - 7.9 7.6 6.2 11 7.2 0.8 3.1 2 1 0 3 3 3 0 Avirulence Effector AvrLm4-7 Rad60-SLD PF11976.8 EAX93549.1 - 0.00082 19.1 0.0 0.0074 16.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAX93549.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family GPS2_interact PF15784.5 EAX93550.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93550.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX93551.1 - 0.47 10.4 8.0 0.56 10.2 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX93552.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX93553.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX93554.1 - 8e-14 51.4 5.7 4e-13 49.0 5.7 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.7 EAX93555.1 - 7.2e-35 119.4 6.1 5.7e-16 58.9 0.4 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93555.1 - 4e-31 107.0 0.7 1.6e-09 38.1 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93555.1 - 2.2e-28 97.9 0.3 2.4e-08 34.1 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93555.1 - 1.3e-19 68.2 1.3 0.0032 17.8 0.0 6.9 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EAX93555.1 - 2.4e-18 65.7 0.1 0.00082 19.7 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat LAGLIDADG_3 PF14528.6 EAX93555.1 - 0.085 13.2 1.9 0.51 10.7 1.5 2.4 2 0 0 2 2 2 0 LAGLIDADG-like domain DUF473 PF04322.12 EAX93557.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF473) NAD_Gly3P_dh_N PF01210.23 EAX93558.1 - 1.9e-40 138.4 0.0 3.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EAX93558.1 - 2.9e-35 121.6 1.1 6.3e-35 120.5 0.3 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EAX93558.1 - 0.017 15.7 0.1 0.3 11.7 0.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Costars PF14705.6 EAX93558.1 - 0.041 14.1 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Costars Hfq PF17209.3 EAX93558.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Hfq protein Pkinase PF00069.25 EAX93560.1 - 4e-51 173.9 0.0 5.4e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93560.1 - 2.1e-25 89.5 0.0 2.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93560.1 - 1.5e-08 34.3 0.0 4.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX93560.1 - 0.00055 19.1 0.2 0.0011 18.1 0.1 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 EAX93560.1 - 0.013 15.2 0.2 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX93560.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GCIP PF13324.6 EAX93561.1 - 0.012 15.3 5.9 0.091 12.3 0.2 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FliD_N PF02465.18 EAX93561.1 - 0.17 12.6 8.9 3.2 8.5 1.0 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FCH PF00611.23 EAX93561.1 - 0.22 11.8 10.1 2.9 8.2 2.2 2.7 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 EAX93561.1 - 0.51 9.6 11.6 0.74 9.1 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.6 EAX93561.1 - 0.71 10.6 8.4 0.5 11.0 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) SLATT_5 PF18160.1 EAX93561.1 - 1 8.6 17.4 0.084 12.2 4.5 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF883 PF05957.13 EAX93561.1 - 1.2 9.8 6.8 0.91 10.2 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2203 PF09969.9 EAX93561.1 - 1.3 9.7 9.1 5.4 7.8 1.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mnd1 PF03962.15 EAX93561.1 - 1.3 9.3 5.7 0.84 10.0 0.2 2.8 3 0 0 3 3 3 0 Mnd1 HTH domain DUF4047 PF13256.6 EAX93561.1 - 2.1 8.5 16.0 0.13 12.4 3.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) HIP1_clath_bdg PF16515.5 EAX93561.1 - 3.5 8.3 18.4 6.3 7.5 5.5 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DnaJ_C PF01556.18 EAX93562.1 - 2.8e-25 89.1 0.0 1.1e-24 87.2 0.0 1.8 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EAX93562.1 - 9.7e-13 48.3 8.6 1.6e-12 47.6 8.6 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 EAX93562.1 - 1.6e-09 37.7 0.1 3.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.19 EAX93562.1 - 0.11 12.5 3.0 0.97 9.5 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EAX93562.1 - 0.57 10.2 9.6 12 6.0 3.2 3.2 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 EAX93562.1 - 0.8 9.9 7.2 1.9 8.7 5.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DUF5351 PF17302.2 EAX93562.1 - 2.5 8.4 18.3 6.3 7.1 0.3 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Myb_DNA-binding PF00249.31 EAX93563.1 - 4.8e-28 97.1 0.5 6.9e-13 48.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93563.1 - 9.1e-25 86.7 0.8 8.3e-16 58.0 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX93563.1 - 0.0086 15.9 0.0 3.1 7.7 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX93563.1 - 0.049 13.7 0.0 4.7 7.3 0.0 2.3 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 EAX93563.1 - 0.064 13.6 1.9 0.41 11.1 0.1 2.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX93563.1 - 0.072 13.3 0.2 0.29 11.4 0.1 2.1 1 1 1 2 2 2 0 Rap1 Myb domain MADF_DNA_bdg PF10545.9 EAX93563.1 - 0.23 11.8 1.9 8.4 6.8 0.1 2.6 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ank_4 PF13637.6 EAX93565.1 - 4e-59 196.3 10.2 1.1e-08 35.5 0.0 10.1 4 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93565.1 - 8.8e-53 176.9 13.4 2.8e-13 50.3 0.8 6.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX93565.1 - 1.2e-45 153.0 6.2 1.9e-08 34.4 0.0 8.7 4 1 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX93565.1 - 8.6e-45 149.3 5.5 2.3e-06 27.8 0.1 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 EAX93565.1 - 1.7e-36 120.1 10.3 0.00013 22.1 0.1 12.0 12 0 0 12 12 12 8 Ankyrin repeat DUF3447 PF11929.8 EAX93565.1 - 1.3e-28 98.8 1.5 1.3e-28 98.8 1.5 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Amidase_3 PF01520.18 EAX93565.1 - 0.017 15.2 0.2 0.048 13.8 0.1 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase DUF249 PF03158.13 EAX93565.1 - 0.19 11.4 6.9 0.42 10.3 0.2 3.0 1 1 1 3 3 3 0 Multigene family 530 protein TPR_19 PF14559.6 EAX93566.1 - 8.1e-10 39.1 0.3 3.6e-08 33.8 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX93566.1 - 8.7e-09 34.8 0.1 0.00059 19.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX93566.1 - 4.7e-08 32.5 0.2 0.014 15.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX93566.1 - 1.1e-06 28.8 3.2 5.3e-05 23.4 0.4 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EAX93566.1 - 8.4e-06 25.6 0.3 0.063 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX93566.1 - 1.5e-05 25.5 0.0 0.15 12.7 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX93566.1 - 9.8e-05 22.5 0.2 0.0044 17.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAX93566.1 - 0.00011 22.2 0.0 0.0008 19.5 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX93566.1 - 0.0002 21.2 0.3 0.24 11.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EAX93566.1 - 0.00099 18.6 0.4 0.0022 17.4 0.4 1.7 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_12 PF13424.6 EAX93566.1 - 0.001 19.3 0.0 1.8 8.9 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX93566.1 - 0.0011 19.6 0.0 1.8 9.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAX93566.1 - 0.0058 16.7 1.9 0.068 13.2 0.0 2.6 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EAX93566.1 - 0.0067 15.7 0.5 1.1 8.4 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAX93566.1 - 0.0093 15.6 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 EAX93566.1 - 0.015 15.9 0.1 2 9.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat USP8_dimer PF08969.11 EAX93566.1 - 0.12 12.6 3.4 0.46 10.7 0.2 3.1 2 1 2 4 4 4 0 USP8 dimerisation domain ABC2_membrane_3 PF12698.7 EAX93566.1 - 1.3 8.0 5.7 4.4 6.3 5.7 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Pih1_fungal_CS PF18482.1 EAX93566.1 - 5.5 7.6 8.9 0.73 10.4 2.8 2.6 2 1 0 2 2 2 0 Fungal Pih1 CS domain Gly-zipper_Omp PF13488.6 EAX93567.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX93567.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX93567.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ARA70 PF12489.8 EAX93568.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX93569.1 - 6.4e-05 22.5 3.2 6.8e-05 22.4 2.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX93569.1 - 0.0058 16.7 1.1 0.011 15.7 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX93569.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Metallophos PF00149.28 EAX93571.1 - 2.9e-09 37.7 0.5 5.9e-09 36.7 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Shisa PF13908.6 EAX93572.1 - 0.00057 20.2 0.2 0.00062 20.1 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EAX93572.1 - 0.0045 16.9 1.2 0.0061 16.5 0.7 1.4 1 1 0 1 1 1 1 TMEM154 protein family FAM176 PF14851.6 EAX93572.1 - 0.11 12.2 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 FAM176 family MCCD1 PF15707.5 EAX93572.1 - 0.33 11.5 1.3 4.6 7.8 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 DUF3215 PF11503.8 EAX93573.1 - 0.067 13.1 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DUF3245 PF11595.8 EAX93574.1 - 0.081 13.4 4.0 0.12 12.9 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RPAP3_C PF13877.6 EAX93575.1 - 2.3 8.8 11.8 63 4.2 0.0 6.3 7 0 0 7 7 7 0 Potential Monad-binding region of RPAP3 SNF2_N PF00176.23 EAX93576.1 - 1.6e-58 198.2 0.4 2.6e-58 197.4 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX93576.1 - 9.1e-21 74.3 0.1 6.5e-20 71.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 EAX93576.1 - 1.9e-17 62.9 2.3 4.4e-12 45.7 0.5 3.8 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 EAX93576.1 - 5.5e-08 32.9 0.0 6.6e-07 29.4 0.0 2.7 3 0 0 3 3 3 1 F/Y rich C-terminus ResIII PF04851.15 EAX93576.1 - 5.6e-05 23.2 3.0 0.00017 21.6 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit FYRN PF05964.14 EAX93576.1 - 0.00027 20.7 0.1 0.00059 19.6 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-DNL PF05180.12 EAX93576.1 - 0.0047 16.8 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 DNL zinc finger DUF4978 PF16349.5 EAX93576.1 - 0.065 12.9 1.5 0.22 11.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4978) DASH_Duo1 PF08651.10 EAX93576.1 - 0.91 9.3 3.7 2.4 8.0 1.7 2.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 Beta-lactamase PF00144.24 EAX93577.1 - 1.5e-30 106.6 0.0 2.1e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3447 PF11929.8 EAX93578.1 - 4.4e-26 90.6 7.9 4.4e-26 90.6 7.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93578.1 - 9.4e-18 64.4 0.4 3.7e-10 40.1 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93578.1 - 4.7e-17 62.4 0.7 3.1e-14 53.3 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93578.1 - 8.4e-17 60.8 0.0 1.1e-06 28.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX93578.1 - 4.6e-14 52.3 0.2 1.9e-09 37.6 0.0 2.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93578.1 - 6.4e-14 50.7 0.3 1.1e-05 25.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat ApoA-II PF04711.13 EAX93579.1 - 0.1 12.8 0.2 3.5 7.9 0.0 3.3 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) LRR_5 PF13306.6 EAX93580.1 - 1.1e-20 73.8 32.7 1.1e-11 44.8 10.2 3.5 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93580.1 - 4.8e-08 32.6 4.5 1.3e-05 24.9 0.1 3.4 2 2 1 3 3 3 2 Leucine rich repeat DUF3021 PF11457.8 EAX93580.1 - 0.013 15.8 0.6 0.032 14.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) S1FA PF04689.13 EAX93580.1 - 0.051 13.7 0.3 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA LRR_5 PF13306.6 EAX93581.1 - 6.9e-20 71.3 77.5 3.1e-09 36.9 23.4 4.5 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93581.1 - 0.0015 18.3 0.9 0.0015 18.3 0.9 5.5 4 1 2 6 6 6 1 Leucine rich repeat LRR_5 PF13306.6 EAX93582.1 - 1e-06 28.7 35.3 5.2e-05 23.2 6.3 3.7 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93582.1 - 0.0026 17.5 17.3 0.031 14.1 0.5 5.1 4 2 1 5 5 5 3 Leucine rich repeat PSP PF04046.16 EAX93583.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DPM3 PF08285.11 EAX93584.1 - 0.17 12.1 0.7 2.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pkinase PF00069.25 EAX93585.1 - 2.1e-53 181.4 0.0 2.4e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93585.1 - 2.1e-29 102.6 0.0 2.8e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93585.1 - 0.0045 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX93585.1 - 0.01 14.8 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX93585.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX93585.1 - 0.14 11.5 0.0 0.6 9.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX93585.1 - 0.16 11.8 0.1 0.39 10.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S30 PF04758.14 EAX93586.1 - 9.6e-26 89.8 3.2 1.1e-25 89.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 RRM_1 PF00076.22 EAX93587.1 - 0.0021 17.8 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Form_Nir_trans PF01226.17 EAX93588.1 - 1.8e-46 158.4 25.0 2e-46 158.2 25.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Gly_rich PF12810.7 EAX93589.1 - 1.2e-19 71.2 18.6 1.5e-19 70.9 18.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Semenogelin PF05474.11 EAX93590.1 - 0.081 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Semenogelin LCAT PF02450.15 EAX93591.1 - 7.7e-33 114.2 0.9 3.5e-29 102.2 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAX93591.1 - 0.00049 19.4 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Inhibitor_I29 PF08246.12 EAX93592.1 - 0.052 14.0 5.7 0.077 13.5 2.3 2.9 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) Sld7_C PF18596.1 EAX93592.1 - 0.062 13.4 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Sld7 C-terminal domain Afaf PF15339.6 EAX93592.1 - 4.6 6.9 12.7 0.55 9.9 7.1 2.0 2 0 0 2 2 2 0 Acrosome formation-associated factor DUF3591 PF12157.8 EAX93593.1 - 1.4e-12 47.1 0.0 1.6e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) AbiEi_3_N PF17194.4 EAX93593.1 - 0.057 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DDE_Tnp_ISL3 PF01610.17 EAX93594.1 - 1.8e-05 24.6 0.2 4.6e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Transposase PSP PF04046.16 EAX93595.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93596.1 - 0.078 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93597.1 - 0.024 15.1 0.5 0.055 13.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) EpuA PF11772.8 EAX93598.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TPR_22 PF18833.1 EAX93599.1 - 0.0083 16.2 0.7 0.024 14.8 0.2 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat Tho2 PF11262.8 EAX93599.1 - 0.085 12.0 3.8 0.095 11.9 3.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 E2F_TDP PF02319.20 EAX93601.1 - 2.6e-17 62.7 0.1 5.9e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 EAX93601.1 - 3.4e-12 46.6 0.0 6.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain DUF2250 PF10007.9 EAX93601.1 - 0.024 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.19 EAX93601.1 - 0.033 14.1 0.1 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB YgaB PF14182.6 EAX93601.1 - 0.043 14.2 0.4 0.14 12.5 0.2 1.9 1 1 1 2 2 2 0 YgaB-like protein LRR_5 PF13306.6 EAX93602.1 - 2.9e-29 101.6 15.5 1.5e-19 70.2 1.4 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93602.1 - 2.2e-11 43.3 0.0 0.00091 18.9 0.1 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EAX93602.1 - 0.00017 21.9 0.3 0.69 10.4 0.0 3.6 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) TPR_MLP1_2 PF07926.12 EAX93603.1 - 0.0078 16.3 0.2 0.0098 15.9 0.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF2089 PF09862.9 EAX93603.1 - 0.048 13.7 0.3 0.07 13.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2089) TcdB_N PF12918.7 EAX93603.1 - 0.29 11.5 7.3 1.5 9.2 0.4 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Spo12 PF05032.12 EAX93603.1 - 7.9 6.5 10.1 0.62 10.0 2.6 2.4 3 0 0 3 3 3 0 Spo12 family ARA70 PF12489.8 EAX93604.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator APG6_N PF17675.1 EAX93605.1 - 0.00028 21.4 8.4 0.00028 21.4 8.4 8.5 4 3 4 8 8 8 3 Apg6 coiled-coil region UPF0242 PF06785.11 EAX93605.1 - 0.0016 18.6 18.3 0.0016 18.6 18.3 8.2 3 2 4 8 8 8 1 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 EAX93605.1 - 0.0019 16.3 26.7 0.0019 16.3 26.7 6.0 1 1 2 5 5 5 2 Prominin ERM PF00769.19 EAX93605.1 - 0.0044 16.9 15.9 0.0044 16.9 15.9 6.6 2 2 3 5 5 5 4 Ezrin/radixin/moesin family ZapB PF06005.12 EAX93605.1 - 0.013 16.0 6.7 0.013 16.0 6.7 13.0 8 3 2 10 10 10 0 Cell division protein ZapB GAS PF13851.6 EAX93605.1 - 0.065 12.6 166.9 0.02 14.2 18.1 8.4 4 3 3 7 7 7 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 EAX93605.1 - 0.4 9.3 115.4 0.0062 15.3 22.6 3.8 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Filament PF00038.21 EAX93605.1 - 2.2 7.8 143.4 0.11 12.1 33.4 5.8 2 2 3 5 5 5 0 Intermediate filament protein HALZ PF02183.18 EAX93605.1 - 3 8.1 0.0 3 8.2 1.3 8.8 8 0 0 8 8 8 0 Homeobox associated leucine zipper Helo_like_N PF17111.5 EAX93606.1 - 0.038 13.3 1.8 0.052 12.9 0.5 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins OmpH PF03938.14 EAX93606.1 - 0.26 11.6 7.5 2.1 8.7 7.2 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FSH1 PF03959.13 EAX93607.1 - 5.3e-29 101.4 0.0 4.6e-27 95.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EAX93607.1 - 1.5e-07 31.3 0.0 0.00095 18.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX93607.1 - 1.7e-06 27.5 0.0 0.00067 19.0 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EAX93607.1 - 0.0005 20.0 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 EAX93607.1 - 0.00088 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EAX93607.1 - 0.0025 18.4 0.2 0.0096 16.5 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EAX93607.1 - 0.0076 15.8 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 EAX93607.1 - 0.028 13.1 0.0 0.053 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 EAX93607.1 - 0.051 13.7 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Cons_hypoth95 PF03602.15 EAX93607.1 - 0.06 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 EAX93607.1 - 0.071 12.8 0.2 0.24 11.0 0.0 1.9 2 1 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Meth_synt_1 PF08267.12 EAX93607.1 - 0.098 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain PE-PPE PF08237.11 EAX93607.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_4 PF08386.10 EAX93607.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein RNase_H PF00075.24 EAX93608.1 - 1.1e-42 145.6 0.1 9.5e-42 142.6 0.0 2.0 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 EAX93608.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like Methyltr_RsmB-F PF01189.17 EAX93610.1 - 2.7e-40 138.2 0.0 6.3e-40 137.0 0.0 1.6 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EAX93610.1 - 0.00045 20.4 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EAX93610.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MH1 PF03165.16 EAX93610.1 - 0.13 12.5 0.1 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 MH1 domain PSP PF04046.16 EAX93611.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93612.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX93614.1 - 1.7e-29 101.7 40.7 1.9e-29 101.5 16.4 5.3 4 1 2 6 6 5 2 Phage tail repeat like RACo_linker PF17650.1 EAX93614.1 - 0.092 12.6 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 RACo linker region DUF4116 PF13475.6 EAX93614.1 - 0.14 11.9 0.1 0.4 10.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX93614.1 - 0.23 11.8 2.1 3.1 8.2 0.3 2.7 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain DUF3839 PF12943.7 EAX93615.1 - 2.8e-158 524.7 12.8 3.5e-158 524.3 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX93615.1 - 0.073 13.5 0.4 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function PRD PF00874.20 EAX93615.1 - 0.28 11.5 0.2 0.28 11.5 0.2 3.1 5 0 0 5 5 5 0 PRD domain KELK PF15796.5 EAX93615.1 - 0.32 11.5 5.5 2.2 8.8 0.9 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly_rich PF12810.7 EAX93616.1 - 1.6e-25 90.5 27.0 1.9e-25 90.2 27.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93617.1 - 3.9e-38 131.8 33.1 4.4e-38 131.6 33.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93618.1 - 4.5e-21 75.9 23.1 5.9e-21 75.5 23.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93619.1 - 1.9e-28 100.0 27.9 2.3e-28 99.8 27.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93620.1 - 2.7e-29 102.8 22.0 3.2e-29 102.6 22.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX93621.1 - 3.9e-28 99.0 33.6 4.8e-28 98.7 33.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Peptidase_M1 PF01433.20 EAX93622.1 - 7.8e-30 104.1 1.5 1.4e-29 103.2 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EAX93622.1 - 4.9e-17 62.7 2.3 8.2e-17 62.0 0.4 2.3 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain GCIP PF13324.6 EAX93623.1 - 0.15 11.6 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pkinase PF00069.25 EAX93624.1 - 3.8e-12 46.1 0.1 4.7e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93624.1 - 6.6e-06 25.6 0.0 7.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF570 PF04489.13 EAX93624.1 - 0.016 13.9 0.3 0.027 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF570) MSG PF02349.15 EAX93624.1 - 0.045 13.9 1.8 0.065 13.4 1.8 1.2 1 0 0 1 1 1 0 Major surface glycoprotein SAM_Ste50p PF09235.10 EAX93624.1 - 0.13 12.5 0.4 0.2 11.9 0.4 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Corona_S2 PF01601.16 EAX93625.1 - 0.0016 17.0 0.9 0.0023 16.5 0.9 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF5478 PF17572.2 EAX93625.1 - 0.082 13.0 0.9 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5478) VPS9 PF02204.18 EAX93626.1 - 1.8e-05 24.9 3.0 9.8e-05 22.5 0.1 3.1 3 1 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Plavaka PF18759.1 EAX93626.1 - 0.026 13.8 1.0 0.035 13.3 0.2 1.6 2 0 0 2 2 2 0 Plavaka transposase Peptidase_C101 PF16218.5 EAX93627.1 - 0.026 13.8 0.9 0.03 13.6 0.9 1.1 1 0 0 1 1 1 0 Peptidase family C101 COX15-CtaA PF02628.15 EAX93628.1 - 0.0022 17.1 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein MtrG PF04210.13 EAX93628.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Ribosomal_S8 PF00410.19 EAX93629.1 - 0.092 12.7 3.6 0.24 11.4 0.9 2.0 1 1 1 2 2 2 0 Ribosomal protein S8 Beach PF02138.18 EAX93631.1 - 7.8e-91 304.3 3.2 1.8e-90 303.1 3.2 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX93631.1 - 1.7e-11 44.1 0.0 5.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH GRAM PF02893.20 EAX93631.1 - 0.0088 15.9 0.2 0.051 13.5 0.2 2.4 1 0 0 1 1 1 1 GRAM domain DUF2526 PF10735.9 EAX93631.1 - 0.16 12.2 0.4 0.4 10.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Myb_DNA-binding PF00249.31 EAX93632.1 - 7.6e-10 38.8 1.4 3.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93632.1 - 5e-08 33.1 1.2 7.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX93632.1 - 0.016 15.1 0.4 0.026 14.4 0.4 1.5 1 1 0 1 1 1 0 Myb DNA-binding like Glyco_trans_A_1 PF09318.10 EAX93632.1 - 0.032 13.9 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A Beach PF02138.18 EAX93633.1 - 2.9e-91 305.7 1.3 6.2e-91 304.6 1.3 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX93633.1 - 3.4e-05 23.9 0.1 0.0001 22.3 0.1 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF3754 PF12576.8 EAX93633.1 - 0.037 14.0 2.4 2.7 7.9 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3754) TcpE PF12648.7 EAX93633.1 - 1.3 9.7 4.2 1.8 9.2 0.1 3.4 3 0 0 3 3 3 0 TcpE family Acetyltransf_7 PF13508.7 EAX93634.1 - 5.4e-09 36.3 0.1 8e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAX93634.1 - 3.4e-08 33.5 0.0 5.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAX93634.1 - 3.9e-08 33.5 0.0 5.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAX93634.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAX93634.1 - 0.0098 16.0 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAX93634.1 - 0.11 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCM PF04072.14 EAX93635.1 - 4.6e-27 95.2 0.0 9.6e-27 94.1 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ubie_methyltran PF01209.18 EAX93635.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GTP_EFTU PF00009.27 EAX93636.1 - 1.1e-38 132.7 0.1 1.7e-38 132.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAX93636.1 - 6.8e-12 45.7 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EAX93636.1 - 1.3e-06 28.5 0.1 7e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX93636.1 - 1.3e-05 25.2 3.4 0.029 14.3 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase Arf PF00025.21 EAX93636.1 - 0.0019 17.7 0.2 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.19 EAX93636.1 - 0.0032 17.1 0.3 0.56 9.8 0.1 2.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D2 PF03144.25 EAX93636.1 - 0.0062 16.9 0.1 0.019 15.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Methyltransf_20 PF12147.8 EAX93636.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Septin PF00735.18 EAX93636.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EAX93636.1 - 0.037 13.6 0.8 0.72 9.4 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 EAX93636.1 - 0.057 13.3 1.3 0.15 12.0 0.1 2.3 3 0 0 3 3 3 0 Elongation factor Tu domain 4 AAA_29 PF13555.6 EAX93636.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EAX93636.1 - 0.17 11.0 2.3 0.39 9.8 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit Ank_2 PF12796.7 EAX93637.1 - 7.1e-67 222.0 40.6 6.9e-18 65.0 7.3 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93637.1 - 6.6e-60 198.8 12.8 3.1e-14 53.1 0.1 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX93637.1 - 4.1e-51 169.3 8.4 1.3e-07 31.8 0.0 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 EAX93637.1 - 1.9e-43 146.0 18.7 1.2e-12 47.7 0.1 5.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93637.1 - 9.8e-37 120.8 7.1 3.2e-06 27.0 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Mic1 PF07035.12 EAX93637.1 - 7.8e-06 25.7 0.1 0.071 12.8 0.0 3.7 2 1 2 4 4 4 2 Colon cancer-associated protein Mic1-like YcxB PF14317.6 EAX93637.1 - 0.0094 15.6 0.1 8.5 6.2 0.0 2.9 3 0 0 3 3 3 2 YcxB-like protein PTS_EIIA_1 PF00358.20 EAX93637.1 - 0.055 13.2 0.8 14 5.5 0.0 3.5 1 1 2 4 4 4 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PH_8 PF15409.6 EAX93637.1 - 0.064 13.5 0.9 10 6.5 0.0 3.5 2 2 0 3 3 3 0 Pleckstrin homology domain CCDC84 PF14968.6 EAX93637.1 - 0.074 12.7 2.1 0.28 10.7 1.7 2.0 1 1 0 1 1 1 0 Coiled coil protein 84 DUF1944 PF09175.10 EAX93637.1 - 0.086 12.7 0.2 0.4 10.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1944) DUF3718 PF12514.8 EAX93637.1 - 0.11 12.7 10.4 1.9 8.7 0.2 5.4 4 3 3 7 7 7 0 Protein of unknown function (DUF3718) Glyco_hydro_53 PF07745.13 EAX93637.1 - 0.17 10.8 8.4 0.053 12.5 1.6 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 53 SAB PF04382.13 EAX93637.1 - 0.19 11.8 2.6 43 4.3 0.1 3.3 3 0 0 3 3 3 0 SAB domain DUF1128 PF06569.11 EAX93638.1 - 0.1 12.6 1.7 1.3 9.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) MtrG PF04210.13 EAX93639.1 - 0.13 12.1 0.1 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pox_E10 PF04805.12 EAX93639.1 - 0.36 10.7 12.5 0.48 10.3 1.6 4.0 3 0 0 3 3 3 0 E10-like protein conserved region UTP15_C PF09384.10 EAX93640.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 UTP15 C terminal Tmemb_161AB PF10268.9 EAX93641.1 - 0.021 13.5 0.2 0.023 13.4 0.2 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Gly_rich PF12810.7 EAX93642.1 - 1.4e-37 129.9 27.8 1.7e-37 129.6 27.8 1.1 1 0 0 1 1 1 1 Glycine rich protein DHHC PF01529.20 EAX93643.1 - 2e-23 82.9 2.4 3.1e-23 82.4 2.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TMEM169 PF15052.6 EAX93643.1 - 0.024 14.8 1.8 0.034 14.3 1.8 1.2 1 0 0 1 1 1 0 TMEM169 protein family Ras PF00071.22 EAX93644.1 - 1.1e-36 125.9 0.0 1.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX93644.1 - 2.6e-27 95.4 0.0 3.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX93644.1 - 3.4e-15 55.9 0.0 4.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX93644.1 - 1.4e-08 34.5 0.2 2.6e-07 30.4 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX93644.1 - 3.7e-08 33.5 0.1 0.0003 20.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX93644.1 - 2.2e-06 27.7 0.0 4.3e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX93644.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX93644.1 - 0.00059 19.6 0.2 0.0045 16.7 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX93644.1 - 0.00062 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EAX93644.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EAX93644.1 - 0.0039 17.5 0.0 0.032 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAX93644.1 - 0.005 16.8 0.1 0.016 15.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EAX93644.1 - 0.011 15.6 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 EAX93644.1 - 0.017 14.7 0.4 0.23 11.0 0.4 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EAX93644.1 - 0.018 14.5 0.1 0.089 12.3 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 EAX93644.1 - 0.077 12.1 0.3 13 4.9 0.0 2.8 2 1 0 3 3 3 0 G-protein alpha subunit DAP3 PF10236.9 EAX93644.1 - 0.1 11.7 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EAX93644.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TIR_2 PF13676.6 EAX93644.1 - 0.14 12.7 0.0 3.7 8.2 0.0 2.2 1 1 1 2 2 2 0 TIR domain NACHT PF05729.12 EAX93644.1 - 0.2 11.6 0.0 0.58 10.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 EAX93645.1 - 7.6e-54 182.8 0.1 9.5e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93645.1 - 1.1e-19 70.8 0.4 3.4e-19 69.1 0.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX93646.1 - 3.2e-71 239.8 0.0 4.8e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93646.1 - 9.9e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EAX93646.1 - 6.7e-18 64.6 0.0 5.4e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EAX93646.1 - 1.2e-07 31.3 0.0 2.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EAX93646.1 - 0.0021 18.0 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX93646.1 - 0.023 13.7 0.0 0.076 11.9 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAX93646.1 - 0.025 14.2 0.1 0.54 9.8 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX93646.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flavodoxin_2 PF02525.17 EAX93647.1 - 1.8e-30 106.2 0.0 2.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_2 PF02525.17 EAX93648.1 - 1.8e-30 106.2 0.0 2.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold PQ-loop PF04193.14 EAX93649.1 - 1.3e-18 66.5 9.4 9.1e-12 44.6 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat Rhomboid PF01694.22 EAX93649.1 - 0.013 15.5 0.4 0.013 15.5 0.4 2.3 3 0 0 3 3 3 0 Rhomboid family DUF2970 PF11174.8 EAX93649.1 - 0.097 12.5 1.1 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PRKCSH PF07915.13 EAX93650.1 - 8.4e-06 26.7 2.4 1.1e-05 26.4 0.8 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EAX93650.1 - 0.00017 21.3 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 EAX93650.1 - 0.0088 16.1 0.8 0.032 14.3 0.1 2.0 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Flavodoxin_2 PF02525.17 EAX93651.1 - 8.7e-19 68.0 0.3 9.6e-19 67.9 0.3 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold DUF2759 PF10958.8 EAX93652.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Flavodoxin_2 PF02525.17 EAX93653.1 - 1.8e-30 106.2 0.0 2.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Pox_A32 PF04665.12 EAX93654.1 - 0.061 12.8 9.1 0.053 13.0 6.1 2.2 1 1 1 2 2 2 0 Poxvirus A32 protein AAA_17 PF13207.6 EAX93654.1 - 2.7 8.4 10.1 0.59 10.6 4.1 2.5 1 1 2 3 3 3 0 AAA domain SART-1 PF03343.13 EAX93655.1 - 1.9e-09 36.7 2.3 1.9e-09 36.7 2.3 3.5 2 1 1 3 3 3 1 SART-1 family NTPase_1 PF03266.15 EAX93656.1 - 2e-06 27.8 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 EAX93656.1 - 0.075 12.9 0.1 4.1 7.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 EAX93656.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EAX93656.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain TBCC PF07986.12 EAX93658.1 - 1.3e-25 89.5 0.0 4.9e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C Aa_trans PF01490.18 EAX93659.1 - 1.1e-41 143.0 44.1 1.2e-41 142.8 44.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EAX93659.1 - 1.8e-06 27.2 33.5 9e-06 25.0 33.5 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3087 PF11286.8 EAX93659.1 - 0.85 9.1 7.4 3.8 7.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Tub PF01167.18 EAX93660.1 - 0.00053 19.8 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Tub family Ank_4 PF13637.6 EAX93661.1 - 3.3e-60 199.7 21.2 8.1e-15 55.0 0.5 9.3 3 1 7 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93661.1 - 3.5e-49 165.3 40.1 7.6e-15 55.3 4.5 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93661.1 - 1.3e-47 158.2 21.3 1.5e-06 28.4 0.1 9.6 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 EAX93661.1 - 5.2e-43 140.1 15.8 1.1e-05 25.4 0.1 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EAX93661.1 - 2.6e-40 136.0 17.4 1.3e-11 44.5 0.2 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX93661.1 - 2.8e-08 33.9 0.0 0.14 12.4 0.0 6.0 4 3 2 6 6 6 1 N terminal of Calcineurin-like phosphoesterase DUF3677 PF12432.8 EAX93661.1 - 0.003 17.8 1.4 1.3e+02 3.0 0.0 6.3 3 3 5 8 8 8 0 Protein of unknown function (DUF3677) Arg_repressor PF01316.21 EAX93661.1 - 0.0075 16.0 5.3 57 3.6 0.0 6.1 7 0 0 7 7 7 0 Arginine repressor, DNA binding domain PrmC_N PF17827.1 EAX93661.1 - 0.0087 16.6 1.2 68 4.1 0.1 5.1 1 1 1 3 3 3 0 PrmC N-terminal domain DUF348 PF03990.14 EAX93661.1 - 0.025 14.3 3.3 1e+02 2.7 0.0 5.4 6 0 0 6 6 6 0 G5-linked-Ubiquitin-like domain VirE_N PF08800.10 EAX93661.1 - 0.18 11.9 0.3 13 5.9 0.0 3.0 2 1 0 2 2 2 0 VirE N-terminal domain ACTL7A_N PF16840.5 EAX93661.1 - 0.27 11.3 12.7 2.2 8.4 0.2 4.3 3 1 1 4 4 4 0 Actin-like protein 7A N-terminus DUF3447 PF11929.8 EAX93662.1 - 1.3e-26 92.3 6.0 1.3e-26 92.3 6.0 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) CRT10 PF08728.10 EAX93662.1 - 0.0038 15.5 0.3 0.0041 15.4 0.3 1.0 1 0 0 1 1 1 1 CRT10 DUF3161 PF11362.8 EAX93663.1 - 0.076 13.0 0.7 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3161) ANAPC4_WD40 PF12894.7 EAX93664.1 - 0.00033 20.9 0.0 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 EAX93664.1 - 0.0008 18.0 2.4 0.0021 16.7 0.1 1.9 1 1 1 2 2 2 1 Utp8 family SLM4 PF16818.5 EAX93664.1 - 0.061 13.3 0.8 0.15 12.0 0.2 1.8 1 1 0 1 1 1 0 Protein SLM4 Ank_2 PF12796.7 EAX93665.1 - 4e-30 104.2 8.0 2.9e-13 50.2 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93665.1 - 1.2e-28 98.3 5.2 9.3e-07 29.0 0.0 6.5 5 1 1 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAX93665.1 - 1.2e-26 92.7 4.6 1.6e-09 38.1 0.1 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93665.1 - 1.1e-21 74.5 4.9 0.022 15.3 0.0 6.8 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX93665.1 - 7.4e-20 70.8 3.2 2.7e-07 30.7 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93665.1 - 2.5e-18 65.8 1.5 2.5e-18 65.8 1.5 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX93667.1 - 4.4e-11 42.7 1.9 1.2e-08 35.0 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX93667.1 - 2.4e-08 33.6 0.1 6.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX93667.1 - 7.1e-08 32.9 0.1 7.7e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93667.1 - 1.3e-07 32.0 0.2 5.9e-07 29.9 0.3 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93667.1 - 0.0026 18.0 0.3 0.0059 16.9 0.2 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DNA_pol_A_exo1 PF01612.20 EAX93668.1 - 2.7e-06 27.2 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease AAA_18 PF13238.6 EAX93670.1 - 9.8e-05 22.9 0.1 0.00065 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EAX93670.1 - 0.0017 17.9 0.0 0.062 12.7 0.0 3.2 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 EAX93670.1 - 0.0019 18.6 0.0 0.013 15.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX93670.1 - 0.082 13.2 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 EAX93670.1 - 0.091 12.9 0.1 3.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Adenylate kinase AAA_28 PF13521.6 EAX93670.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EAX93670.1 - 0.12 12.1 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EAX93670.1 - 0.14 12.3 0.0 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Adaptin_binding PF10199.9 EAX93670.1 - 0.65 10.6 0.0 0.65 10.6 0.0 3.5 3 2 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 DUF4107 PF13389.6 EAX93671.1 - 5.4e-37 127.4 2.1 6.6e-37 127.2 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX93671.1 - 0.076 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Xpo1 PF08389.12 EAX93673.1 - 5.1e-06 26.6 5.1 5.1e-06 26.6 5.1 4.4 4 2 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 EAX93673.1 - 0.059 13.3 8.4 0.24 11.3 0.4 3.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain HEAT PF02985.22 EAX93673.1 - 0.15 12.4 0.2 5.1 7.6 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat BRE1 PF08647.11 EAX93674.1 - 0.079 13.0 1.0 0.079 13.0 1.0 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Bromodomain PF00439.25 EAX93675.1 - 1.8e-25 88.8 0.2 3.9e-25 87.7 0.2 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX93675.1 - 0.00025 21.2 0.0 0.00074 19.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation NAM-associated PF14303.6 EAX93675.1 - 0.00062 20.5 3.0 0.00084 20.1 3.0 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain ARGLU PF15346.6 EAX93675.1 - 0.15 11.9 7.1 0.06 13.2 4.5 1.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF737 PF05300.11 EAX93675.1 - 0.26 11.6 8.0 0.41 11.0 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) LRR_5 PF13306.6 EAX93678.1 - 6.8e-39 132.8 25.9 2.4e-24 85.7 11.3 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93678.1 - 1.1e-09 38.0 1.2 0.0024 17.6 0.1 4.5 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EAX93678.1 - 0.0096 16.3 5.8 0.34 11.4 0.7 3.9 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAX93678.1 - 0.27 11.4 3.2 3.1 8.1 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat zf-Tim10_DDP PF02953.15 EAX93678.1 - 0.36 10.5 9.3 9.8 5.9 0.1 3.3 2 1 1 3 3 3 0 Tim10/DDP family zinc finger APG6_N PF17675.1 EAX93679.1 - 0.00025 21.6 61.8 0.0015 19.1 9.5 3.9 2 1 2 4 4 4 3 Apg6 coiled-coil region Spectrin PF00435.21 EAX93679.1 - 0.0036 17.8 6.0 0.0036 17.8 6.0 5.8 1 1 5 6 6 6 1 Spectrin repeat Bacillus_HBL PF05791.11 EAX93679.1 - 0.0053 16.6 15.1 0.0053 16.6 15.1 4.2 1 1 2 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) CALCOCO1 PF07888.11 EAX93679.1 - 0.025 13.5 52.9 0.021 13.7 14.8 2.3 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SnoaL_3 PF13474.6 EAX93679.1 - 0.063 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain FUSC PF04632.12 EAX93679.1 - 0.74 8.3 3.6 1.4 7.3 0.1 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family UPF0242 PF06785.11 EAX93679.1 - 1.3 9.0 65.0 0.39 10.8 16.9 4.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EAX93679.1 - 3.7 7.6 54.2 0.27 11.3 3.4 6.6 2 1 5 7 7 7 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EAX93679.1 - 3.9 6.3 62.6 0.48 9.3 17.8 3.7 1 1 2 3 3 3 0 Spc7 kinetochore protein UPF0184 PF03670.13 EAX93679.1 - 5.2 7.5 17.4 0.48 10.8 2.3 4.5 3 1 1 5 5 5 0 Uncharacterised protein family (UPF0184) DUF3447 PF11929.8 EAX93680.1 - 8.6e-26 89.7 5.5 8.6e-26 89.7 5.5 3.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93680.1 - 1.2e-22 80.3 0.3 2.4e-08 34.5 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93680.1 - 4.6e-18 65.3 0.8 0.00023 21.7 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93680.1 - 1.1e-12 47.8 0.4 2.7e-06 27.6 0.0 5.8 6 1 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EAX93680.1 - 2.6e-11 43.5 0.2 0.00078 19.7 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93680.1 - 1.3e-10 40.6 1.2 0.0031 17.9 0.0 5.9 7 0 0 7 7 7 2 Ankyrin repeat Trp_ring PF18669.1 EAX93680.1 - 0.19 11.9 0.2 0.92 9.7 0.0 2.0 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain Cullin_Nedd8 PF10557.9 EAX93681.1 - 7.3e-12 45.1 0.1 3.6e-11 42.9 0.1 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain IBD PF10416.9 EAX93682.1 - 5.1e-31 107.4 0.6 6.7e-31 107.0 0.6 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4452 PF14618.6 EAX93683.1 - 0.0093 15.8 8.0 0.0093 15.8 8.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4452) Pep1_7 PF17232.2 EAX93683.1 - 0.014 15.8 9.3 0.38 11.2 0.2 3.3 2 1 2 4 4 4 0 Elicitor peptide 1-7 Hamartin PF04388.12 EAX93683.1 - 0.025 13.3 4.9 0.032 12.9 4.9 1.3 1 0 0 1 1 1 0 Hamartin protein ZapD PF07072.11 EAX93683.1 - 0.092 12.5 0.2 0.76 9.5 0.0 2.2 1 1 2 3 3 3 0 Cell division protein Pkinase_Tyr PF07714.17 EAX93684.1 - 3.3e-49 167.5 0.0 7.9e-49 166.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX93684.1 - 8.1e-47 159.8 0.0 2.1e-46 158.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAX93684.1 - 0.0069 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Cg6151-P PF10233.9 EAX93684.1 - 0.036 14.4 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P APH PF01636.23 EAX93684.1 - 0.044 13.7 0.4 0.081 12.8 0.4 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RcsD_ABL PF16359.5 EAX93685.1 - 0.33 11.1 2.0 0.43 10.7 0.1 2.1 2 1 0 2 2 2 0 RcsD-ABL domain LRR_4 PF12799.7 EAX93686.1 - 3.2e-08 33.7 10.0 0.0006 20.1 0.7 3.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX93686.1 - 1.8e-07 30.8 7.7 0.0004 20.1 0.3 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EAX93686.1 - 0.00022 20.8 1.3 0.00074 19.1 1.3 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EAX93686.1 - 0.0025 18.1 3.8 11 7.0 0.0 4.2 3 1 0 3 3 3 1 Leucine Rich Repeat Ada3 PF10198.9 EAX93686.1 - 0.0062 16.7 0.1 0.0081 16.3 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 LRR_6 PF13516.6 EAX93686.1 - 0.016 15.2 5.3 14 6.0 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Val_tRNA-synt_C PF10458.9 EAX93686.1 - 0.029 14.6 0.1 0.07 13.4 0.1 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Med27 PF11571.8 EAX93687.1 - 0.018 15.4 0.2 0.086 13.2 0.0 2.2 3 0 0 3 3 3 0 Mediator complex subunit 27 Beta_helix PF13229.6 EAX93688.1 - 0.0036 17.2 4.5 0.0036 17.2 4.5 2.5 1 1 1 2 2 2 2 Right handed beta helix region NS3_envE PF02723.14 EAX93688.1 - 0.064 13.3 2.3 0.19 11.9 2.3 1.7 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF4957 PF16318.5 EAX93688.1 - 0.08 12.9 7.4 1.3 8.9 0.9 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4957) MULE PF10551.9 EAX93689.1 - 1.3e-09 38.3 0.3 1.3e-09 38.3 0.3 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX93689.1 - 0.019 13.8 0.1 0.037 12.9 0.1 1.5 1 0 0 1 1 1 0 Transposase, Mutator family TM1586_NiRdase PF14512.6 EAX93690.1 - 3.4e-22 79.1 0.0 5.7e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 EAX93690.1 - 4.3e-09 36.6 0.3 0.0014 18.7 0.1 3.2 2 2 1 3 3 3 2 Nitroreductase family Thioredoxin PF00085.20 EAX93692.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin IBD PF10416.9 EAX93693.1 - 1.3e-34 118.9 4.9 1.3e-34 118.9 4.9 2.1 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD SapB_1 PF05184.15 EAX93694.1 - 1.7e-34 117.4 39.5 7.1e-11 41.9 2.3 6.3 7 0 0 7 7 7 4 Saposin-like type B, region 1 SapB_2 PF03489.17 EAX93694.1 - 2.4e-29 101.1 41.4 2.6e-10 40.2 0.5 5.9 7 0 0 7 7 5 4 Saposin-like type B, region 2 DENN PF02141.21 EAX93694.1 - 3.2e-07 30.5 0.0 0.54 10.2 0.0 3.3 3 0 0 3 3 3 3 DENN (AEX-3) domain HTH_23 PF13384.6 EAX93694.1 - 5.1e-05 22.9 0.6 7.8 6.4 0.0 5.1 5 0 0 5 5 5 1 Homeodomain-like domain CDT1_C PF16679.5 EAX93694.1 - 0.0011 19.4 0.7 20 5.7 0.0 4.1 3 1 1 4 4 4 0 DNA replication factor Cdt1 C-terminal domain PqqD PF05402.12 EAX93694.1 - 0.003 17.8 2.6 35 4.8 0.0 4.4 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) GnsAB_toxin PF08178.11 EAX93694.1 - 0.0061 16.5 8.2 1.5 8.8 0.2 3.6 4 0 0 4 4 4 2 GnsA/GnsB toxin of bacterial toxin-antitoxin system UBA_6 PF18039.1 EAX93694.1 - 0.0068 16.3 0.0 73 3.4 0.0 4.4 4 0 0 4 4 4 0 UBA-like domain Katanin_con80 PF13925.6 EAX93694.1 - 0.01 15.9 2.5 4.9 7.2 0.0 3.9 4 0 0 4 4 4 0 con80 domain of Katanin Peptidase_S41_N PF11918.8 EAX93694.1 - 0.034 14.4 0.1 15 5.8 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Meleagrin PF08189.11 EAX93694.1 - 0.056 13.1 16.3 2.5 7.9 0.1 5.0 5 0 0 5 5 4 0 Meleagrin/Cygnin family Get5_C PF18514.1 EAX93694.1 - 0.15 11.8 3.4 28 4.6 0.0 3.3 3 0 0 3 3 3 0 Get5 C-terminal domain Casc1_N PF15927.5 EAX93694.1 - 0.19 11.4 1.1 16 5.1 0.1 3.2 4 0 0 4 4 4 0 Cancer susceptibility candidate 1 N-terminus Thioredoxin_3 PF13192.6 EAX93694.1 - 0.22 11.6 11.6 2.9 8.0 0.2 3.8 4 0 0 4 4 4 0 Thioredoxin domain DUF445 PF04286.12 EAX93694.1 - 0.23 11.2 0.2 29 4.3 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF445) C1_1 PF00130.22 EAX93694.1 - 1.6 8.7 14.4 5.4 7.0 0.9 4.4 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Uteroglobin PF01099.17 EAX93694.1 - 3.2 8.2 9.2 3.8 7.9 0.2 3.6 4 0 0 4 4 4 0 Uteroglobin family DUF3456 PF11938.8 EAX93694.1 - 8.8 6.8 24.5 68 3.9 0.2 6.1 3 3 1 4 4 4 0 TLR4 regulator and MIR-interacting MSAP PSP PF04046.16 EAX93695.1 - 0.087 12.7 0.8 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93696.1 - 0.033 14.7 4.8 11 7.2 0.2 3.5 3 1 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAX93697.1 - 0.059 13.5 0.1 16 5.8 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain DUF4107 PF13389.6 EAX93698.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX93699.1 - 0.0031 17.2 0.0 0.008 15.8 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Amidase02_C PF12123.8 EAX93700.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX93701.1 - 5e-71 238.1 4.5 6e-71 237.8 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX93701.1 - 0.17 10.3 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX93702.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF1493 PF07377.12 EAX93704.1 - 0.091 13.2 0.5 0.21 12.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX93704.1 - 0.5 10.4 3.3 14 5.9 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX93705.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX93706.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Aminotran_1_2 PF00155.21 EAX93708.1 - 3.1e-38 131.9 0.0 4.3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SNase PF00565.17 EAX93709.1 - 2e-23 82.9 0.0 3.2e-06 27.6 0.0 4.5 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 EAX93709.1 - 4.4e-13 49.3 0.1 1.9e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 Tudor domain SspH PF08141.12 EAX93709.1 - 0.076 13.2 0.1 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Small acid-soluble spore protein H family ELMO_CED12 PF04727.13 EAX93710.1 - 0.044 13.9 0.1 0.079 13.1 0.1 1.5 1 0 0 1 1 1 0 ELMO/CED-12 family DUF4108 PF13390.6 EAX93712.1 - 1e-57 194.1 3.9 1.1e-57 194.0 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX93712.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX93714.1 - 8.1e-07 28.7 2.3 8.1e-07 28.7 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX93714.1 - 3.5e-05 23.6 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX93714.1 - 8.3e-05 22.9 0.2 0.00053 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX93714.1 - 9.4e-05 22.5 2.7 0.0002 21.4 2.6 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93714.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93714.1 - 0.0023 17.8 0.6 0.0083 15.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93714.1 - 0.0024 17.5 0.5 0.016 14.8 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93714.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX93714.1 - 0.061 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX93714.1 - 0.069 12.7 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX93714.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX93714.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX93714.1 - 0.13 12.7 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX93714.1 - 0.48 10.7 3.7 14 6.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DEAD PF00270.29 EAX93715.1 - 7.1e-28 97.6 0.3 9.3e-28 97.2 0.3 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX93715.1 - 6.2e-14 52.4 0.0 7.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EAX93715.1 - 0.00044 19.9 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EAX93715.1 - 0.00048 20.4 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX93715.1 - 0.00064 20.2 0.9 0.015 15.7 0.9 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EAX93715.1 - 0.0016 18.8 0.1 0.0024 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAX93715.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EAX93715.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX93715.1 - 0.043 12.9 0.0 0.14 11.1 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EAX93715.1 - 0.11 12.2 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 EAX93715.1 - 0.39 10.5 2.1 1.6 8.5 0.2 2.3 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DHR10 PF18595.1 EAX93716.1 - 0.0098 15.9 2.1 0.0098 15.9 2.1 5.6 4 1 0 5 5 5 1 Designed helical repeat protein 10 domain Helicase_Sgs1 PF11408.8 EAX93716.1 - 0.15 12.1 3.5 1.1 9.4 0.3 3.5 3 1 0 3 3 3 0 Sgs1 RecQ helicase Beach PF02138.18 EAX93718.1 - 6.7e-18 65.0 5.5 1.9e-10 40.6 2.8 2.3 2 0 0 2 2 2 2 Beige/BEACH domain zf-C2H2_8 PF15909.5 EAX93718.1 - 0.049 13.9 0.1 0.09 13.1 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon PcfK PF14058.6 EAX93718.1 - 0.064 13.5 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 PcfK-like protein Swi3 PF07962.12 EAX93720.1 - 0.044 13.8 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 SSP160 PF06933.11 EAX93721.1 - 7.5 4.6 10.8 10 4.2 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F5_F8_type_C PF00754.25 EAX93722.1 - 0.0033 17.5 0.1 0.084 13.0 0.0 2.1 2 0 0 2 2 2 2 F5/8 type C domain zf-C3HC4_3 PF13920.6 EAX93723.1 - 4.8e-13 48.8 11.4 1e-12 47.7 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX93723.1 - 5e-11 42.3 7.5 9.7e-11 41.4 7.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAX93723.1 - 5.1e-11 42.7 9.0 1.4e-10 41.3 9.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX93723.1 - 2.9e-09 36.6 9.2 7.5e-09 35.3 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX93723.1 - 4.2e-09 36.1 8.8 1e-08 34.9 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAX93723.1 - 9.6e-07 29.0 10.5 1.9e-06 28.0 10.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EAX93723.1 - 1.3e-06 28.3 5.4 1.3e-06 28.3 5.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX93723.1 - 3.8e-05 23.5 10.7 9.7e-05 22.3 10.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAX93723.1 - 0.00058 19.9 7.2 0.0012 18.9 7.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EAX93723.1 - 0.00075 19.6 12.3 0.00075 19.6 12.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 EAX93723.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 EAX93723.1 - 0.029 14.2 6.5 0.066 13.1 6.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EAX93723.1 - 0.12 12.5 7.5 0.3 11.2 7.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 EAX93723.1 - 1.7 8.7 8.7 6.1 7.0 8.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EAX93723.1 - 4.2 7.1 9.5 8 6.2 8.8 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Svf1 PF08622.10 EAX93724.1 - 0.068 13.2 7.2 0.029 14.4 4.4 1.6 1 1 1 2 2 2 0 Svf1-like N-terminal lipocalin domain PRKCSH-like PF12999.7 EAX93725.1 - 1.5e-06 28.1 1.2 1.5e-06 28.1 1.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like DUF4136 PF13590.6 EAX93725.1 - 0.047 14.3 0.3 0.089 13.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) Acyl-CoA_ox_N PF14749.6 EAX93725.1 - 0.089 13.4 1.1 0.15 12.7 0.2 1.8 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF3447 PF11929.8 EAX93726.1 - 3e-08 33.5 1.8 5.4e-08 32.7 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93726.1 - 0.025 15.1 0.1 0.17 12.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93726.1 - 0.08 13.5 0.1 3.3 8.4 0.0 2.4 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) PIN_5 PF08745.11 EAX93727.1 - 0.052 13.0 0.2 0.14 11.5 0.1 1.8 2 0 0 2 2 2 0 PINc domain ribonuclease BHD_1 PF10403.9 EAX93729.1 - 0.052 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Pox_A32 PF04665.12 EAX93730.1 - 2.5e-06 27.1 0.5 2.9e-06 26.9 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAX93730.1 - 0.038 14.3 0.9 0.055 13.8 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2666 PF10869.8 EAX93731.1 - 0.028 14.6 1.2 0.07 13.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF5446 PF17522.2 EAX93732.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PSP PF04046.16 EAX93736.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MIR PF02815.19 EAX93737.1 - 0.0085 16.0 0.0 0.96 9.3 0.0 2.4 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 EAX93737.1 - 0.037 13.2 0.3 0.2 10.8 0.2 2.0 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor IBP39 PF11422.8 EAX93738.1 - 1.6e-68 230.0 1.1 2.1e-68 229.6 1.1 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 EAX93738.1 - 4.6e-19 68.7 0.1 1.3e-18 67.2 0.0 1.7 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD SF3A2 PF16835.5 EAX93738.1 - 0.032 14.6 0.1 0.098 13.0 0.1 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) HSP70 PF00012.20 EAX93740.1 - 3e-27 95.1 8.1 3e-27 95.1 8.1 3.8 2 1 1 3 3 3 1 Hsp70 protein FGGY_C PF02782.16 EAX93740.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Cullin PF00888.22 EAX93741.1 - 2.5e-73 247.7 25.6 4.2e-73 247.0 25.6 1.3 1 0 0 1 1 1 1 Cullin family HC2 PF07382.11 EAX93741.1 - 0.013 15.5 20.8 0.032 14.3 20.8 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Cullin_Nedd8 PF10557.9 EAX93741.1 - 0.017 15.2 1.6 0.15 12.2 0.2 3.1 2 0 0 2 2 2 0 Cullin protein neddylation domain DUF3960 PF13142.6 EAX93741.1 - 0.069 13.3 2.3 0.38 10.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3960) Voldacs PF03517.13 EAX93741.1 - 0.57 10.3 7.4 1.2 9.2 6.6 2.0 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling Pox_Ag35 PF03286.14 EAX93741.1 - 8.1 6.2 19.4 11 5.7 16.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ion_trans PF00520.31 EAX93743.1 - 5.8e-06 25.7 12.9 1.3e-05 24.5 12.9 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EAX93743.1 - 0.017 13.8 8.6 0.0076 15.0 2.9 2.0 2 0 0 2 2 2 0 Polycystin cation channel Cep57_MT_bd PF06657.13 EAX93744.1 - 0.08 13.4 0.3 0.08 13.4 0.3 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pkinase PF00069.25 EAX93745.1 - 4.4e-73 245.9 0.0 5.8e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93745.1 - 2.1e-38 132.1 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93745.1 - 3.7e-10 39.6 0.0 1.1e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX93745.1 - 3.4e-06 26.2 0.0 6.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX93745.1 - 6.5e-05 22.4 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX93745.1 - 0.009 16.0 0.0 0.096 12.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family MULE PF10551.9 EAX93746.1 - 1.4e-10 41.4 0.2 4e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX93746.1 - 0.025 13.4 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family SPC22 PF04573.12 EAX93747.1 - 7.1e-21 74.4 0.1 7.9e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit MutS_V PF00488.21 EAX93748.1 - 2.7e-40 138.4 0.2 5.9e-40 137.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAX93748.1 - 2.3e-21 76.9 1.7 3.8e-21 76.2 0.7 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EAX93748.1 - 4e-07 30.3 3.6 4.5e-06 26.9 2.2 3.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EAX93748.1 - 0.0072 16.6 0.2 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.6 EAX93748.1 - 0.0078 16.2 0.0 0.037 14.0 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAX93748.1 - 0.015 15.8 0.5 0.015 15.8 0.5 3.3 2 2 0 2 2 2 0 AAA domain LAGLIDADG_2 PF03161.13 EAX93748.1 - 0.028 14.4 2.4 0.044 13.8 0.5 2.4 3 0 0 3 3 3 0 LAGLIDADG DNA endonuclease family AAA_21 PF13304.6 EAX93748.1 - 0.082 12.7 9.6 0.29 10.9 0.4 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PurL_C PF16904.5 EAX93748.1 - 0.12 12.7 0.2 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus ABC_tran PF00005.27 EAX93748.1 - 0.46 11.0 1.9 2.3 8.8 0.1 3.0 4 0 0 4 4 4 0 ABC transporter Pkinase PF00069.25 EAX93749.1 - 2.5e-52 177.9 0.1 9.9e-52 175.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93749.1 - 1.6e-46 158.7 0.0 2.8e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX93749.1 - 0.031 13.6 0.9 0.061 12.6 0.0 2.0 3 0 0 3 3 3 0 Kinase-like FAS_N PF17828.1 EAX93751.1 - 0.013 15.5 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX93752.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX93752.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAX93753.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX93753.1 - 0.038 14.0 0.2 0.054 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX93754.1 - 1.9e-154 512.1 12.6 2.4e-154 511.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2362 PF10154.9 EAX93755.1 - 0.0011 18.1 2.6 0.0015 17.5 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) TPR_MLP1_2 PF07926.12 EAX93756.1 - 0.046 13.8 0.2 0.058 13.5 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX93756.1 - 0.088 12.6 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX93756.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Vps39_2 PF10367.9 EAX93757.1 - 3.7e-14 53.1 0.2 2.3e-13 50.5 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 HNH PF01844.23 EAX93757.1 - 0.079 13.1 0.2 0.35 11.1 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease Chromo PF00385.24 EAX93758.1 - 3.8e-15 55.5 5.9 2.1e-13 49.9 2.9 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAX93758.1 - 1.7e-06 28.0 1.2 0.0011 19.1 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain HmuY PF14064.6 EAX93758.1 - 0.0013 19.0 0.4 0.0017 18.6 0.4 1.1 1 0 0 1 1 1 1 HmuY protein Tudor_3 PF18115.1 EAX93758.1 - 0.0018 18.1 0.1 0.036 13.9 0.2 2.6 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain GDPD PF03009.17 EAX93758.1 - 0.068 12.9 0.6 0.08 12.7 0.6 1.3 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Vasohibin PF14822.6 EAX93758.1 - 0.073 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Vasohibin Rax2 PF12768.7 EAX93760.1 - 0.021 14.3 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Insulin_TMD PF17870.1 EAX93760.1 - 0.058 13.5 1.2 0.76 9.9 0.4 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF5383 PF17355.2 EAX93760.1 - 0.083 13.3 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5383) CagD PF16567.5 EAX93760.1 - 0.11 12.3 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Pathogenicity island component CagD Herpes_UL25 PF01499.16 EAX93761.1 - 4.1 5.8 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family CDC45 PF02724.14 EAX93762.1 - 0.1 10.9 15.3 0.17 10.1 15.3 1.4 1 0 0 1 1 1 0 CDC45-like protein HAUS-augmin3 PF14932.6 EAX93763.1 - 0.0065 16.1 1.6 0.0092 15.6 1.6 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Arm-DNA-bind_5 PF17293.2 EAX93763.1 - 7.2 7.1 14.2 2 8.9 7.4 3.2 2 2 0 2 2 2 0 Arm DNA-binding domain DUF4107 PF13389.6 EAX93764.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAX93765.1 - 1.6e-08 34.3 1.0 3.5e-08 33.2 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAX93765.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAX93765.1 - 0.065 13.1 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 AbiJ_NTD4 PF18863.1 EAX93766.1 - 0.028 14.9 0.3 0.057 13.9 0.3 1.7 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX93766.1 - 0.033 14.3 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 VirK protein DUF641 PF04859.12 EAX93767.1 - 0.02 15.3 1.7 0.028 14.7 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 EAX93767.1 - 0.11 12.6 0.2 0.16 12.0 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Pertus-S5-tox PF09276.10 EAX93767.1 - 0.2 11.7 0.1 0.52 10.4 0.1 1.7 1 1 0 1 1 1 0 Pertussis toxin S5 subunit bZIP_1 PF00170.21 EAX93767.1 - 0.33 11.1 0.0 0.33 11.1 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor Exostosin PF03016.15 EAX93768.1 - 1.5e-40 139.3 0.1 1.8e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Exostosin family WD40 PF00400.32 EAX93769.1 - 1.2e-32 111.4 18.8 5.4e-07 30.2 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93769.1 - 2e-17 63.3 0.8 3.1e-06 27.4 0.5 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX93769.1 - 2e-07 31.1 2.1 0.0014 18.6 0.4 3.4 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAX93769.1 - 4.7e-07 29.4 0.1 0.026 13.9 0.0 3.2 1 1 2 3 3 3 3 WD40-like domain Frtz PF11768.8 EAX93769.1 - 0.03 12.6 0.1 1.5 7.1 0.1 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DPPIV_N PF00930.21 EAX93769.1 - 0.03 13.1 1.2 0.58 8.9 0.4 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BMP2K_C PF15282.6 EAX93769.1 - 0.039 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Nup160 PF11715.8 EAX93769.1 - 0.049 12.3 0.8 0.42 9.2 0.0 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EAX93769.1 - 0.12 12.3 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3447 PF11929.8 EAX93770.1 - 5.4e-36 122.4 5.7 5.4e-36 122.4 5.7 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93770.1 - 5.2e-11 43.0 1.6 0.00021 21.8 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93770.1 - 7e-07 29.7 0.4 0.016 15.8 0.0 4.9 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX93770.1 - 1.9e-06 28.0 0.4 0.0003 21.1 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EAX93770.1 - 4.3e-06 26.7 1.1 0.036 14.6 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 EAX93771.1 - 2e-28 98.8 11.0 9.7e-16 58.1 3.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93771.1 - 3.1e-28 97.8 0.9 2.2e-09 37.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93771.1 - 8.3e-26 89.3 2.4 1.7e-07 31.3 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX93771.1 - 3.1e-23 81.5 4.7 2e-10 40.7 0.3 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93771.1 - 6.1e-22 75.4 0.1 6.2e-06 26.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat ThiS-like PF14453.6 EAX93771.1 - 0.031 14.3 1.6 1.2 9.3 0.3 2.8 1 1 2 3 3 3 0 ThiS-like ubiquitin I_LWEQ PF01608.17 EAX93771.1 - 0.036 14.3 0.5 1.2 9.4 0.1 1.9 1 1 1 2 2 2 0 I/LWEQ domain PH_8 PF15409.6 EAX93771.1 - 0.055 13.8 0.2 32 4.9 0.0 3.0 1 1 2 3 3 3 0 Pleckstrin homology domain DUF3718 PF12514.8 EAX93771.1 - 0.15 12.2 2.5 6.9 6.9 0.2 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3718) SAB PF04382.13 EAX93771.1 - 0.19 11.9 2.2 28 4.9 0.1 3.1 2 1 1 3 3 3 0 SAB domain DUF4147 PF13660.6 EAX93771.1 - 0.33 10.5 3.0 0.97 8.9 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4147) RibD_C PF01872.17 EAX93772.1 - 4.5e-19 69.1 0.0 5.7e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF2114 PF09887.9 EAX93772.1 - 0.14 10.6 0.0 0.35 9.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2114) RRM_1 PF00076.22 EAX93773.1 - 5.7e-11 42.1 0.1 9.2e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4746 PF15928.5 EAX93773.1 - 0.015 14.8 0.1 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Aminotran_5 PF00266.19 EAX93774.1 - 7.8e-22 77.7 0.0 1.5e-21 76.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Apolipoprotein PF01442.18 EAX93775.1 - 0.0084 16.0 29.3 0.0084 16.0 29.3 7.2 1 1 4 6 6 6 3 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 EAX93775.1 - 5.8 6.6 253.2 0.027 14.3 42.3 7.3 1 1 5 7 7 7 0 Family with sequence similarity 184, A and B RibD_C PF01872.17 EAX93776.1 - 1.1e-15 58.0 0.0 1.3e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Cupin_2 PF07883.11 EAX93777.1 - 0.0045 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Sgf11_N PF18519.1 EAX93777.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain NHR2 PF08788.11 EAX93778.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 NHR2 domain like DUF3447 PF11929.8 EAX93779.1 - 1.6e-40 136.9 5.9 1.6e-40 136.9 5.9 4.5 4 2 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93779.1 - 1e-34 119.0 10.0 5e-17 62.3 1.1 4.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93779.1 - 1.4e-32 111.7 9.7 4.2e-08 33.6 0.1 6.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX93779.1 - 1.5e-32 110.6 6.7 1.9e-07 31.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX93779.1 - 7.3e-25 86.7 5.2 1.6e-11 44.2 1.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93779.1 - 4.1e-23 78.9 11.3 8.1e-07 28.9 0.1 7.4 7 1 0 7 7 7 4 Ankyrin repeat LEM PF03020.15 EAX93779.1 - 0.09 12.4 0.1 37 4.0 0.0 3.5 3 0 0 3 3 3 0 LEM domain Apolipoprotein PF01442.18 EAX93780.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Myb_DNA-binding PF00249.31 EAX93781.1 - 6.8e-29 99.8 0.1 3.7e-16 59.0 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93781.1 - 8.2e-23 80.4 1.1 2.5e-17 62.9 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX93781.1 - 3.7e-06 27.0 0.1 0.0012 18.8 0.1 3.0 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAX93781.1 - 2e-05 24.4 0.4 0.0027 17.6 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like NinE PF05322.11 EAX93781.1 - 0.0019 18.0 0.2 0.011 15.6 0.1 2.2 1 1 1 2 2 2 1 NINE Protein Myb_DNA-bind_2 PF08914.11 EAX93781.1 - 0.0066 16.6 0.6 0.6 10.3 0.4 2.5 1 1 1 2 2 2 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX93781.1 - 0.28 11.6 3.8 0.37 11.2 0.9 2.5 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain TPT PF03151.16 EAX93782.1 - 1.2e-05 24.8 10.7 1.4e-05 24.6 9.0 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 EAX93782.1 - 0.0013 19.0 10.4 0.0013 19.0 10.4 3.7 2 2 0 3 3 3 1 EamA-like transporter family RRM_1 PF00076.22 EAX93783.1 - 6.5e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4783 PF16022.5 EAX93783.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) DUF3361 PF11841.8 EAX93784.1 - 0.0055 16.7 0.1 0.0055 16.7 0.1 3.8 6 0 0 6 6 6 1 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 EAX93784.1 - 0.03 14.9 1.6 0.86 10.2 0.1 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAX93784.1 - 0.051 14.1 0.1 17 6.0 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat Katanin_con80 PF13925.6 EAX93784.1 - 0.11 12.5 3.1 15 5.6 0.0 3.8 5 0 0 5 5 5 0 con80 domain of Katanin DUF3492 PF11997.8 EAX93784.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) LRR_5 PF13306.6 EAX93786.1 - 1.3e-89 296.7 127.2 6.6e-21 74.6 13.1 7.4 2 2 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93786.1 - 5e-16 58.2 10.7 0.23 11.2 0.0 9.9 4 3 8 12 12 12 9 Leucine rich repeat LRR_4 PF12799.7 EAX93786.1 - 0.016 15.6 29.6 5.8 7.5 0.0 9.8 6 3 5 12 12 12 0 Leucine Rich repeats (2 copies) Sigma_reg_N PF13800.6 EAX93787.1 - 0.035 14.4 1.0 0.035 14.4 1.0 2.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Orf78 PF06024.12 EAX93787.1 - 0.035 14.4 1.3 0.061 13.6 1.3 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Ank_2 PF12796.7 EAX93788.1 - 1.1e-48 163.8 0.0 1.3e-14 54.5 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93788.1 - 2.9e-38 128.6 0.0 7.2e-06 26.2 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX93788.1 - 2.8e-36 123.1 0.0 1e-09 38.4 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX93788.1 - 3.3e-32 110.4 0.0 3.6e-09 37.0 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93788.1 - 1.5e-26 89.5 0.0 0.0012 19.1 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Rad4 PF03835.15 EAX93788.1 - 0.042 13.5 3.0 13 5.5 0.0 3.9 3 2 2 5 5 5 0 Rad4 transglutaminase-like domain Peptidase_S49 PF01343.18 EAX93788.1 - 0.049 13.6 0.1 24 4.8 0.0 3.3 3 2 1 4 4 4 0 Peptidase family S49 DUF5005 PF16396.5 EAX93788.1 - 0.066 11.9 0.3 6.7 5.3 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5005) HCV_core PF01542.18 EAX93788.1 - 0.099 13.0 0.1 46 4.5 0.0 3.4 2 1 1 4 4 4 0 Hepatitis C virus core protein PLN_propep PF16485.5 EAX93788.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protealysin propeptide Glyco_transf_6 PF03414.13 EAX93788.1 - 0.14 10.9 0.1 4.2 6.0 0.0 3.0 1 1 1 3 3 3 0 Glycosyltransferase family 6 Mago-bind PF09282.10 EAX93788.1 - 5.3 7.0 5.5 1.1e+02 2.8 0.0 3.8 4 0 0 4 4 4 0 Mago binding Dopey_N PF04118.14 EAX93789.1 - 8.9e-51 172.8 1.6 8.9e-51 172.8 1.6 3.3 2 1 0 2 2 2 1 Dopey, N-terminal CAAP1 PF15335.6 EAX93789.1 - 1 9.9 4.7 3.3 8.3 0.3 3.8 4 0 0 4 4 4 0 Caspase activity and apoptosis inhibitor 1 Gly_rich PF12810.7 EAX93791.1 - 6.6e-43 147.4 27.7 7.9e-43 147.1 27.7 1.1 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX93792.1 - 4.8e-83 275.5 57.7 2.3e-27 95.5 2.9 5.8 2 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93792.1 - 1e-15 57.2 8.2 0.034 13.9 0.2 8.0 6 2 2 8 8 8 6 Leucine rich repeat LRR_5 PF13306.6 EAX93793.1 - 6.6e-18 64.9 0.9 8.3e-18 64.6 0.8 1.2 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93793.1 - 8.3e-14 51.1 0.0 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAX93793.1 - 0.072 13.5 0.0 0.2 12.1 0.0 1.8 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) MHB PF16525.5 EAX93794.1 - 0.66 10.3 4.4 0.28 11.5 0.3 2.4 2 0 0 2 2 2 0 Haemophore, haem-binding AAA_13 PF13166.6 EAX93794.1 - 2.9 6.4 54.8 0.013 14.2 31.5 2.3 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EAX93796.1 - 1.4e-40 138.8 0.0 2.9e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAX93796.1 - 1e-09 38.0 0.0 2.9e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EAX93796.1 - 1.1e-08 34.9 0.0 1.6e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EAX93796.1 - 1e-05 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EAX93796.1 - 3.2e-05 23.3 0.0 6.5e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 EAX93796.1 - 3.7e-05 23.9 0.0 0.00018 21.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAX93796.1 - 8.6e-05 23.0 0.0 0.015 15.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EAX93796.1 - 0.00018 21.5 0.2 0.0024 17.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EAX93796.1 - 0.00063 19.5 0.0 0.0031 17.3 0.0 2.1 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 EAX93796.1 - 0.0012 19.1 0.2 0.033 14.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 EAX93796.1 - 0.0038 16.8 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EAX93796.1 - 0.0056 16.8 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EAX93796.1 - 0.008 15.6 0.0 0.024 14.0 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAX93796.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EAX93796.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX93796.1 - 0.029 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EAX93796.1 - 0.039 13.0 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 EAX93796.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX93796.1 - 0.051 13.8 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAX93796.1 - 0.082 13.3 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Gly_rich PF12810.7 EAX93797.1 - 3e-48 164.9 29.2 3.8e-48 164.5 29.2 1.1 1 0 0 1 1 1 1 Glycine rich protein Pox_A31 PF05771.11 EAX93797.1 - 0.029 14.4 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A31 protein WEMBL PF05701.11 EAX93798.1 - 0.00025 19.9 33.7 0.00032 19.5 33.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light BRE1 PF08647.11 EAX93798.1 - 0.00067 19.7 14.0 0.00067 19.7 14.0 4.5 2 1 2 4 4 4 2 BRE1 E3 ubiquitin ligase SOGA PF11365.8 EAX93798.1 - 0.027 15.6 2.0 0.027 15.6 2.0 4.4 2 1 2 4 4 4 0 Protein SOGA Ycf15 PF10705.9 EAX93798.1 - 0.035 14.3 0.8 0.085 13.0 0.1 2.0 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative ZapB PF06005.12 EAX93798.1 - 0.096 13.1 57.5 0.074 13.5 7.6 6.1 2 2 3 5 5 5 0 Cell division protein ZapB PRKG1_interact PF15898.5 EAX93798.1 - 0.2 12.6 43.6 0.67 10.9 11.2 4.6 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 EAX93798.1 - 0.32 11.0 43.0 0.41 10.7 18.1 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 EAX93798.1 - 1.4 9.3 52.3 0.035 14.4 13.2 3.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) CALCOCO1 PF07888.11 EAX93798.1 - 3.7 6.3 38.5 0.3 9.9 27.8 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 EAX93798.1 - 8.5 7.1 42.0 2.6 8.7 7.3 5.4 1 1 4 5 5 5 0 Initiation control protein YabA Cnd1 PF12717.7 EAX93799.1 - 0.0018 18.3 0.3 0.0037 17.3 0.1 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EAX93799.1 - 0.014 15.4 1.0 0.24 11.4 0.0 2.5 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF5071 PF16804.5 EAX93799.1 - 0.064 13.5 4.9 0.13 12.5 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5071) Ank_4 PF13637.6 EAX93800.1 - 8.7e-161 520.4 74.9 1.5e-12 47.7 0.2 19.1 1 1 19 20 20 20 20 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93800.1 - 2.9e-157 511.7 123.7 5.7e-14 52.5 2.4 10.6 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93800.1 - 3.4e-130 419.4 67.6 6.9e-07 29.4 0.7 20.0 20 0 0 20 20 20 19 Ankyrin repeat Ank_3 PF13606.6 EAX93800.1 - 2.1e-112 353.3 28.4 2.6e-05 24.3 0.0 19.9 20 0 0 20 20 20 19 Ankyrin repeat Ank_5 PF13857.6 EAX93800.1 - 6.9e-83 271.6 73.7 2e-09 37.5 0.5 12.7 6 6 7 13 13 13 13 Ankyrin repeats (many copies) YcxB PF14317.6 EAX93800.1 - 6.3e-10 38.6 0.0 56 3.5 0.0 10.4 10 0 0 10 10 10 0 YcxB-like protein MetallophosN PF16371.5 EAX93800.1 - 5.8e-09 36.1 15.8 2.2 8.6 0.0 11.0 3 3 8 12 12 12 2 N terminal of Calcineurin-like phosphoesterase Mic1 PF07035.12 EAX93800.1 - 0.0003 20.6 13.9 16 5.2 0.1 9.4 3 3 3 10 10 10 0 Colon cancer-associated protein Mic1-like Csm1_N PF18504.1 EAX93800.1 - 0.006 16.9 23.3 73 3.8 0.0 11.2 9 2 2 11 11 11 0 Csm1 N-terminal domain DUF5395 PF17373.2 EAX93800.1 - 0.013 16.1 6.1 1e+02 3.6 0.0 5.4 5 0 0 5 5 5 0 Family of unknown function (DUF5395) Smr PF01713.21 EAX93800.1 - 0.027 14.8 17.1 11 6.5 0.1 7.2 3 3 2 5 5 5 0 Smr domain DUF1299 PF06975.11 EAX93800.1 - 0.68 10.0 13.3 94 3.2 0.1 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1299) DUF3718 PF12514.8 EAX93800.1 - 4.4 7.5 55.1 19 5.5 0.1 14.1 13 6 5 18 18 18 0 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAX93801.1 - 2e-86 283.3 30.3 1.3e-13 51.2 0.2 8.8 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93801.1 - 1.8e-80 265.6 54.2 1.5e-15 57.5 1.9 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAX93801.1 - 5.5e-69 225.8 33.0 6.7e-09 35.8 0.2 10.0 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 EAX93801.1 - 1.5e-58 187.8 13.8 3.3e-06 27.0 0.1 10.0 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 EAX93801.1 - 9.8e-53 175.5 35.6 2.6e-11 43.5 0.7 6.3 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 EAX93801.1 - 1.1e-05 25.6 0.7 36 4.7 0.0 6.1 1 1 7 8 8 8 0 Ribosomal protein S6 PH_8 PF15409.6 EAX93801.1 - 0.00019 21.6 1.4 17 5.8 0.1 5.3 2 2 5 7 7 7 0 Pleckstrin homology domain YcxB PF14317.6 EAX93801.1 - 0.00089 18.9 0.0 7.5 6.3 0.0 5.2 7 0 0 7 7 7 1 YcxB-like protein Mic1 PF07035.12 EAX93801.1 - 0.0016 18.2 4.8 5.8 6.6 0.1 5.4 4 3 3 7 7 7 1 Colon cancer-associated protein Mic1-like Csm1_N PF18504.1 EAX93801.1 - 0.0053 17.1 12.8 98 3.4 0.0 7.9 8 1 0 9 9 9 0 Csm1 N-terminal domain BRCT_2 PF16589.5 EAX93801.1 - 0.011 16.2 4.3 9.9 6.7 1.0 4.8 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain PrmC_N PF17827.1 EAX93801.1 - 0.05 14.2 16.4 8.7 7.0 0.4 6.8 4 2 4 8 8 8 0 PrmC N-terminal domain AA_kinase PF00696.28 EAX93801.1 - 0.056 13.0 3.4 1.2 8.7 0.4 2.5 1 1 2 3 3 3 0 Amino acid kinase family Peptidase_Mx PF15887.5 EAX93801.1 - 0.072 12.5 10.4 1.2 8.5 0.7 3.1 1 1 1 3 3 3 0 Putative zinc-binding metallo-peptidase DUF3718 PF12514.8 EAX93801.1 - 0.62 10.3 19.8 41 4.4 0.1 7.7 6 2 3 9 9 9 0 Protein of unknown function (DUF3718) Fer2 PF00111.27 EAX93801.1 - 2.6 8.1 4.3 46 4.1 0.1 4.7 6 0 0 6 6 6 0 2Fe-2S iron-sulfur cluster binding domain Lipocalin_8 PF16585.5 EAX93801.1 - 2.7 8.4 6.7 22 5.5 0.3 3.7 1 1 2 4 4 4 0 Lipocalin-like domain Ank_2 PF12796.7 EAX93803.1 - 3e-17 63.0 6.0 4.1e-11 43.3 2.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93803.1 - 1.1e-13 51.4 5.0 2.7e-07 31.0 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93803.1 - 1e-10 41.6 0.3 9.9e-06 25.7 0.0 4.1 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93803.1 - 9.9e-09 34.8 4.7 0.032 14.8 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EAX93803.1 - 1.5e-06 28.4 0.6 0.00033 20.9 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 EAX93803.1 - 0.00011 22.1 31.2 0.00013 21.9 9.7 3.8 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) DUF5054 PF16477.5 EAX93803.1 - 0.029 14.1 0.5 0.058 13.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) DUF5556 PF17711.1 EAX93803.1 - 0.21 11.5 0.0 2.8 7.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5556) GAS PF13851.6 EAX93804.1 - 0.00071 19.0 33.2 0.00071 19.0 33.2 8.3 4 2 4 8 8 8 2 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EAX93804.1 - 0.0033 17.7 26.0 0.0033 17.7 26.0 8.5 2 2 6 8 8 8 3 Autophagy protein 16 (ATG16) ADIP PF11559.8 EAX93804.1 - 0.0073 16.4 18.2 0.0073 16.4 18.2 10.6 3 3 6 9 9 9 3 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 EAX93804.1 - 0.0074 16.0 25.1 0.0074 16.0 25.1 8.9 3 2 6 9 9 9 4 Domain of unknown function (DUF4201) DivIC PF04977.15 EAX93804.1 - 0.011 15.4 4.8 0.011 15.4 4.8 16.4 6 5 9 17 17 17 0 Septum formation initiator Fib_alpha PF08702.10 EAX93804.1 - 0.012 15.9 12.7 0.012 15.9 12.7 11.0 4 3 8 12 12 12 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EAX93804.1 - 0.015 16.0 12.5 0.015 16.0 12.5 13.0 3 3 7 10 10 10 0 Initiation control protein YabA Ank PF00023.30 EAX93806.1 - 1.6e-39 132.6 8.6 1.3e-08 34.9 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EAX93806.1 - 2.2e-38 130.1 7.9 4.5e-15 55.8 0.3 7.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93806.1 - 3e-38 130.3 14.2 6.7e-16 58.7 2.7 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX93806.1 - 3.5e-34 116.6 5.6 3.5e-34 116.6 5.6 3.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX93806.1 - 1e-28 96.2 12.2 2.7e-05 24.2 0.1 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX93806.1 - 3.1e-26 91.1 3.9 4.5e-11 42.8 0.1 4.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Zn_peptidase PF04228.13 EAX93807.1 - 0.018 14.5 0.3 0.029 13.8 0.3 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2652 PF10851.8 EAX93807.1 - 0.26 11.4 2.1 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) KxDL PF10241.9 EAX93807.1 - 3.2 8.1 13.7 0.52 10.6 5.9 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Ribosomal_L30 PF00327.20 EAX93808.1 - 8.8e-15 54.3 2.9 2.3e-14 53.0 2.9 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 EAX93808.1 - 6.4e-13 48.7 16.8 1.2e-12 47.9 16.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain HsdM_N PF12161.8 EAX93808.1 - 0.054 14.1 0.4 0.1 13.2 0.4 1.5 1 1 0 1 1 1 0 HsdM N-terminal domain MycE_N PF17843.1 EAX93808.1 - 0.1 13.1 1.3 0.28 11.7 1.1 1.8 2 0 0 2 2 2 0 MycE methyltransferase N-terminal DUF1515 PF07439.11 EAX93808.1 - 0.79 9.8 2.7 3 7.9 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Meis_PKNOX_N PF16493.5 EAX93809.1 - 0.075 13.4 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 eIF-4B PF06273.11 EAX93809.1 - 0.58 9.2 2.8 0.8 8.7 2.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PCRF PF03462.18 EAX93810.1 - 2.5 7.9 10.7 2.6 7.8 10.7 1.0 1 0 0 1 1 1 0 PCRF domain FapA PF03961.13 EAX93810.1 - 3.9 6.0 14.9 3.9 6.0 14.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A IBD PF10416.9 EAX93811.1 - 1.5e-36 125.2 0.2 2e-36 124.8 0.2 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD LRR_6 PF13516.6 EAX93812.1 - 6.1e-07 29.0 3.9 0.0026 17.7 0.1 5.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 EAX93812.1 - 9.9e-07 29.0 14.6 0.07 13.6 0.0 6.9 6 3 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX93812.1 - 0.034 14.7 11.5 4.1 8.3 0.0 6.4 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 EAX93812.1 - 1.6 8.5 8.8 2.4 8.0 0.1 4.4 4 2 0 4 4 4 0 Leucine rich repeat 7TMR-HDED PF07697.11 EAX93813.1 - 0.11 12.6 0.0 0.33 11.0 0.0 2.0 2 1 0 2 2 2 0 7TM-HD extracellular ATP-synt_E_2 PF08112.11 EAX93813.1 - 3.3 8.0 6.9 1.6 9.1 1.0 3.1 3 0 0 3 3 3 0 ATP synthase epsilon subunit ERp29 PF07749.12 EAX93814.1 - 3.9e-06 27.7 0.1 5.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin PF00085.20 EAX93814.1 - 0.0029 17.6 0.1 0.0067 16.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin DUF3447 PF11929.8 EAX93815.1 - 2.3e-21 75.5 2.8 2.3e-21 75.5 2.8 3.9 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX93815.1 - 3.3e-16 59.7 1.1 1e-11 45.3 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93815.1 - 4.4e-15 55.8 4.3 1.2e-08 35.3 0.6 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93815.1 - 1e-11 44.0 3.5 2.3e-06 27.5 0.3 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX93815.1 - 4.8e-08 33.1 0.4 3.1e-06 27.4 0.3 3.2 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX93815.1 - 1e-07 32.1 0.6 3.3e-06 27.3 0.3 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF3849 PF12960.7 EAX93815.1 - 0.044 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Raco_middle PF17651.1 EAX93815.1 - 0.075 12.7 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 RACo middle region Spc7 PF08317.11 EAX93816.1 - 0.85 8.4 82.0 0.068 12.0 14.4 4.4 1 1 2 4 4 4 0 Spc7 kinetochore protein LRR_5 PF13306.6 EAX93817.1 - 1.8e-37 128.1 36.6 1.3e-19 70.4 9.1 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93817.1 - 0.00066 19.4 3.5 1.3 8.8 0.0 4.0 4 0 0 4 4 4 2 Leucine rich repeat S-layer PF07752.11 EAX93817.1 - 0.058 12.4 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 S-layer protein PSP PF04046.16 EAX93818.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX93819.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX93820.1 - 0.034 14.6 0.7 0.069 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX93821.1 - 7.4e-21 74.0 6.3 3.2e-16 59.1 1.6 4.4 6 0 0 6 6 6 2 Phage tail repeat like YonK PF09642.10 EAX93823.1 - 0.018 15.2 0.2 0.14 12.3 0.2 2.5 1 1 1 2 2 2 0 YonK protein EF-hand_5 PF13202.6 EAX93823.1 - 0.13 11.8 0.3 0.3 10.6 0.3 1.5 1 0 0 1 1 1 0 EF hand Man-6-P_recep PF02157.15 EAX93824.1 - 1e-05 24.8 0.1 3.1e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EAX93824.1 - 2.9e-05 24.1 12.5 0.0076 16.1 1.2 4.7 4 1 1 5 5 5 2 Autophagy-related protein 27 Nodulin_late PF07127.11 EAX93824.1 - 0.082 13.3 9.4 0.15 12.4 0.4 4.2 3 0 0 3 3 3 0 Late nodulin protein C2-set PF05790.15 EAX93824.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin C2-set domain PRA-PH PF01503.17 EAX93825.1 - 0.12 12.8 3.5 8 7.0 4.2 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4108 PF13390.6 EAX93826.1 - 8.4e-63 210.6 8.3 9.4e-63 210.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX93828.1 - 0.0013 18.6 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX93828.1 - 0.0032 17.8 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX93828.1 - 0.0037 17.6 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX93828.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX93828.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX93828.1 - 0.043 13.4 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX93828.1 - 0.07 12.9 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX93828.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Vps26 PF03643.15 EAX93829.1 - 9.8e-47 159.2 0.0 1.2e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EAX93829.1 - 0.018 15.1 0.5 25 4.9 0.1 3.3 2 2 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain BCIP PF13862.6 EAX93831.1 - 5.4e-24 85.1 0.0 1.2e-23 84.0 0.0 1.5 1 1 0 1 1 1 1 p21-C-terminal region-binding protein IMS PF00817.20 EAX93834.1 - 1.9e-43 148.1 0.1 1.5e-42 145.2 0.0 2.4 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.8 EAX93834.1 - 3.1e-12 47.2 1.1 6.1e-12 46.3 0.4 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EAX93834.1 - 4.9e-08 32.8 0.2 1.2e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 IMS family HHH motif SPC12 PF06645.13 EAX93835.1 - 1.6e-16 60.2 2.4 1.8e-16 60.0 2.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Adeno_E3_15_3 PF03307.14 EAX93836.1 - 0.031 14.2 0.4 0.12 12.4 0.4 2.0 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region TolA_bind_tri PF16331.5 EAX93836.1 - 1.7 8.8 30.7 0.23 11.6 3.9 4.6 4 1 0 4 4 4 0 TolA binding protein trimerisation DUF812 PF05667.11 EAX93836.1 - 9.6 5.0 53.2 1.3 7.9 27.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DSHCT PF08148.12 EAX93837.1 - 1.9e-41 141.5 0.0 3.9e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EAX93837.1 - 1.1e-16 61.1 0.3 3.9e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ski2_N PF17911.1 EAX93837.1 - 3.5e-08 33.3 0.0 7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region Helicase_C PF00271.31 EAX93837.1 - 1.3e-05 25.5 0.0 6.8e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX93837.1 - 5.1e-05 23.3 0.5 0.0002 21.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 EAX93837.1 - 0.031 14.2 5.6 0.23 11.4 0.4 2.3 1 1 0 2 2 2 0 rRNA-processing arch domain ATPase_2 PF01637.18 EAX93837.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAX93837.1 - 0.092 13.0 0.0 0.46 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain Got1 PF04178.12 EAX93838.1 - 1.2e-07 32.1 12.5 1.7e-07 31.7 12.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Tenui_PVC2 PF06656.11 EAX93838.1 - 0.3 8.9 0.4 0.38 8.6 0.4 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Ank_2 PF12796.7 EAX93842.1 - 1.5e-34 118.4 16.5 3.6e-16 59.5 1.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX93842.1 - 2.8e-32 110.5 5.4 2.8e-32 110.5 5.4 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93842.1 - 2.3e-28 98.2 1.2 4.9e-10 39.7 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX93842.1 - 2.4e-25 87.8 0.1 4.2e-07 30.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX93842.1 - 4.4e-20 69.6 0.7 3.4e-06 27.0 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX93842.1 - 1.3e-19 70.0 0.2 9.3e-10 38.6 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) COPIIcoated_ERV PF07970.12 EAX93843.1 - 4e-47 160.9 0.6 6.9e-47 160.1 0.6 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX93843.1 - 1.7e-22 79.6 0.1 4e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF824 PF05688.11 EAX93843.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF5582 PF17819.1 EAX93844.1 - 0.01 16.3 0.1 0.011 16.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF2691 PF10903.8 EAX93844.1 - 0.049 13.5 0.2 0.049 13.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) Peptidase_M20 PF01546.28 EAX93846.1 - 2.1e-14 53.7 0.0 3.4e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAX93846.1 - 2.9e-07 30.4 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Minor_capsid_3 PF12691.7 EAX93847.1 - 0.0079 16.6 0.6 0.32 11.4 0.8 2.6 2 0 0 2 2 2 1 Minor capsid protein from bacteriophage RRM_1 PF00076.22 EAX93849.1 - 1.9e-10 40.4 1.3 8.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX93849.1 - 0.0001 21.9 0.0 0.0014 18.3 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OxoDH_E1alpha_N PF12573.8 EAX93849.1 - 0.003 17.3 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Cullin PF00888.22 EAX93850.1 - 1.4e-14 53.6 0.1 6.7e-14 51.4 0.0 2.0 2 1 0 2 2 2 1 Cullin family DUF3447 PF11929.8 EAX93852.1 - 7e-21 74.0 5.3 7e-21 74.0 5.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93852.1 - 0.0035 17.9 0.4 0.1 13.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93852.1 - 0.0063 17.1 0.1 0.54 10.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93852.1 - 0.31 11.7 1.5 19 6.2 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EAX93853.1 - 2.6e-18 65.9 1.4 1.2e-07 31.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX93853.1 - 1.5e-17 63.7 0.0 1.1e-10 41.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93853.1 - 1.9e-16 59.6 0.0 1.5e-06 28.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX93853.1 - 5.2e-15 55.8 0.4 1.1e-14 54.8 0.5 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93853.1 - 5.2e-14 51.0 0.1 9.6e-05 22.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Sas10_Utp3 PF04000.15 EAX93854.1 - 0.023 15.3 0.6 0.023 15.3 0.6 3.1 3 1 0 3 3 3 0 Sas10/Utp3/C1D family Arm PF00514.23 EAX93854.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HALZ PF02183.18 EAX93855.1 - 0.00012 22.2 8.1 0.0025 18.0 2.4 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper DUF3287 PF11690.8 EAX93855.1 - 0.0044 16.8 2.6 0.014 15.2 0.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3287) DUF4391 PF14335.6 EAX93855.1 - 0.008 15.9 0.6 0.008 15.9 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4391) WXG100 PF06013.12 EAX93855.1 - 0.019 15.2 1.3 0.06 13.6 1.3 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG bZIP_2 PF07716.15 EAX93855.1 - 0.02 15.0 6.8 0.23 11.6 0.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.22 EAX93855.1 - 0.022 15.0 6.3 0.024 14.8 6.3 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 EAX93855.1 - 0.034 13.9 1.6 0.034 13.9 1.6 2.1 2 0 0 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 EAX93855.1 - 0.04 14.4 7.9 0.63 10.5 1.1 2.1 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ApoB100_C PF12491.8 EAX93855.1 - 0.04 13.9 2.9 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Syntaxin-6_N PF09177.11 EAX93855.1 - 0.078 13.5 2.5 0.1 13.2 2.5 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DivIVA PF05103.13 EAX93855.1 - 0.095 12.8 7.0 0.09 12.9 1.6 2.0 1 1 1 2 2 2 0 DivIVA protein Nif11 PF07862.11 EAX93855.1 - 0.21 11.9 3.2 0.12 12.7 0.8 1.9 2 1 0 2 2 2 0 Nif11 domain M PF02370.16 EAX93855.1 - 1.2 9.9 10.6 7.6 7.5 3.1 2.9 2 1 0 2 2 2 0 M protein repeat XhlA PF10779.9 EAX93855.1 - 1.3 9.3 6.6 2.5 8.4 0.9 2.0 1 1 1 2 2 2 0 Haemolysin XhlA BST2 PF16716.5 EAX93855.1 - 3.4 8.3 10.6 7.2 7.3 2.5 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4140 PF13600.6 EAX93855.1 - 3.6 8.1 7.4 10 6.6 1.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rap_GAP PF02145.15 EAX93856.1 - 6.7e-39 133.3 3.0 8.1e-39 133.1 0.6 2.4 2 0 0 2 2 2 1 Rap/ran-GAP DDE_Tnp_ISL3 PF01610.17 EAX93857.1 - 2e-05 24.5 0.2 5.3e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Transposase Cu2_monooxygen PF01082.20 EAX93857.1 - 0.021 15.1 0.5 0.074 13.3 0.2 2.1 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain AA_permease PF00324.21 EAX93858.1 - 7.7e-66 222.6 35.1 9.8e-66 222.3 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EAX93858.1 - 8.4e-41 140.4 0.0 5.3e-37 127.9 0.1 3.1 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 EAX93858.1 - 2.4e-20 72.8 47.5 3.9e-20 72.1 47.5 1.3 1 0 0 1 1 1 1 Amino acid permease PG_binding_2 PF08823.11 EAX93859.1 - 0.026 14.8 0.1 0.49 10.7 0.2 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Dimer_Tnp_hAT PF05699.14 EAX93859.1 - 0.12 12.2 0.9 2 8.3 0.0 2.6 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region DUF87 PF01935.17 EAX93859.1 - 0.12 12.4 0.6 0.39 10.8 0.6 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain Meiosis_expr PF15163.6 EAX93860.1 - 0.02 15.6 1.6 0.024 15.3 0.7 1.6 2 0 0 2 2 2 0 Meiosis-expressed Amidase02_C PF12123.8 EAX93862.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX93863.1 - 1.1e-72 243.5 4.8 1.3e-72 243.3 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX93865.1 - 7.6e-38 128.4 27.9 2.6e-32 110.7 15.7 5.4 4 2 2 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX93865.1 - 0.13 12.0 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX93867.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX93868.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_6 PF13516.6 EAX93869.1 - 1.2e-07 31.2 32.8 0.074 13.1 0.3 9.8 10 0 0 10 10 10 4 Leucine Rich repeat Filament PF00038.21 EAX93869.1 - 0.00051 19.7 13.2 0.0012 18.5 13.2 1.6 1 0 0 1 1 1 1 Intermediate filament protein ENT PF03735.14 EAX93869.1 - 0.13 12.3 2.6 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 ENT domain UPF0242 PF06785.11 EAX93869.1 - 0.16 12.1 16.1 0.13 12.4 14.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nbl1_Borealin_N PF10444.9 EAX93869.1 - 1.2 8.8 8.4 6.4 6.5 1.2 2.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal LRR_1 PF00560.33 EAX93869.1 - 4.7 8.2 29.1 21 6.2 0.3 9.3 8 2 1 9 9 9 0 Leucine Rich Repeat SHIPPO-rpt PF07004.12 EAX93870.1 - 0.003 18.4 62.1 0.047 14.6 0.4 10.5 7 4 0 7 7 7 4 Sperm-tail PG-rich repeat ArfGap PF01412.18 EAX93871.1 - 2.9e-30 104.7 1.0 5.2e-30 103.9 1.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 EAX93871.1 - 4.7e-19 68.8 0.6 8.2e-19 68.1 0.6 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EAX93871.1 - 6e-05 23.4 0.2 0.0013 19.1 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EAX93871.1 - 0.0016 18.7 0.2 0.0028 17.9 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.7 EAX93871.1 - 0.046 14.3 0.0 0.12 12.9 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PH_17 PF18012.1 EAX93871.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PH domain T5orf172 PF10544.9 EAX93875.1 - 0.00056 20.4 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX93875.1 - 0.0084 15.7 0.9 0.09 12.3 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX93875.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain DUF3839 PF12943.7 EAX93876.1 - 7.9e-154 510.1 12.9 1e-153 509.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX93876.1 - 0.059 13.7 0.6 14 6.1 0.0 3.2 3 0 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX93876.1 - 0.13 12.8 1.4 5.3 7.6 0.0 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Plasmodium_Vir PF05795.11 EAX93878.1 - 0.00023 20.7 2.5 0.00035 20.1 2.5 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF4366 PF14283.6 EAX93878.1 - 0.0021 18.1 1.8 0.0087 16.1 1.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) VSP PF03302.13 EAX93878.1 - 0.0024 16.8 0.3 0.004 16.1 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD99L2 PF12301.8 EAX93878.1 - 0.0036 17.6 0.5 0.0075 16.6 0.5 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF5385 PF17359.2 EAX93878.1 - 0.012 15.2 0.1 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM154 PF15102.6 EAX93878.1 - 0.015 15.2 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family ABC2_membrane_3 PF12698.7 EAX93878.1 - 0.021 13.9 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4690 PF15756.5 EAX93878.1 - 0.028 15.0 0.0 0.077 13.6 0.0 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4448 PF14610.6 EAX93878.1 - 0.048 13.4 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EAX93878.1 - 0.1 13.5 0.0 0.28 12.1 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX93878.1 - 0.13 12.2 2.3 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Syndecan domain TFIIS_C PF01096.18 EAX93880.1 - 1.7e-14 53.4 2.0 2.7e-14 52.7 2.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 EAX93880.1 - 0.0012 19.4 9.4 0.0048 17.4 9.4 2.0 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RTT107_BRCT_6 PF16771.5 EAX93880.1 - 0.012 15.7 0.9 0.012 15.7 0.9 1.9 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Elf1 PF05129.13 EAX93880.1 - 0.013 15.5 0.3 0.029 14.4 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like UPF0160 PF03690.13 EAX93880.1 - 0.086 12.5 1.0 0.15 11.7 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Arena_ncap_C PF17290.2 EAX93880.1 - 0.26 10.6 3.2 19 4.6 0.1 3.0 3 0 0 3 3 3 0 Arenavirus nucleocapsid C-terminal domain DUF4949 PF16307.5 EAX93880.1 - 0.29 11.3 3.1 4 7.6 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4949) UPF0515 PF15135.6 EAX93880.1 - 0.68 9.2 5.9 2 7.7 5.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 Lar_restr_allev PF14354.6 EAX93880.1 - 4.1 7.9 6.4 0.51 10.7 1.7 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar NAGLU_C PF12972.7 EAX93882.1 - 0.013 15.0 0.5 0.019 14.5 0.5 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain FlaC_arch PF05377.11 EAX93882.1 - 0.025 15.0 1.6 0.24 11.8 0.1 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CorA PF01544.18 EAX93882.1 - 0.044 13.1 0.7 0.059 12.7 0.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 EAX93882.1 - 0.23 12.0 4.4 0.13 12.8 1.3 2.1 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 LPP PF04728.13 EAX93882.1 - 0.28 11.6 2.1 0.86 10.0 0.5 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper YabA PF06156.13 EAX93882.1 - 0.89 10.2 4.3 5.3 7.7 1.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 EAX93882.1 - 8.8 6.4 8.9 12 6.0 5.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ras PF00071.22 EAX93883.1 - 2e-34 118.5 0.0 2.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX93883.1 - 1.5e-26 93.0 0.0 2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX93883.1 - 3.5e-12 46.1 0.0 4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX93883.1 - 6.9e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX93883.1 - 0.0028 17.0 0.0 0.0067 15.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX93883.1 - 0.034 13.7 0.0 0.068 12.7 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX93883.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Voltage_CLC PF00654.20 EAX93884.1 - 1.8e-65 221.6 32.2 5e-65 220.1 30.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel TrkA_C PF02080.21 EAX93884.1 - 2.9e-10 39.8 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain Nucleoporin_N PF08801.11 EAX93885.1 - 2.9e-09 36.2 5.8 1.9e-07 30.2 5.8 2.9 1 1 0 1 1 1 1 Nup133 N terminal like PWWP PF00855.17 EAX93886.1 - 0.035 14.5 0.7 0.094 13.1 0.4 1.8 1 1 0 1 1 1 0 PWWP domain DASH_Dad1 PF08649.10 EAX93886.1 - 0.17 12.1 5.4 6.1 7.1 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad1 BMFP PF04380.13 EAX93886.1 - 0.18 12.3 4.0 0.56 10.7 0.4 3.0 3 0 0 3 3 3 0 Membrane fusogenic activity Spore_III_AB PF09548.10 EAX93886.1 - 1.5 8.9 6.0 0.27 11.3 2.3 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Lzipper-MIP1 PF14389.6 EAX93886.1 - 2.1 8.7 9.7 3.8 7.9 2.2 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 C4bp_oligo PF18453.1 EAX93886.1 - 2.5 8.4 5.3 0.45 10.8 0.9 2.2 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha LicD PF04991.13 EAX93886.1 - 5.2 7.1 15.6 34 4.5 15.6 2.1 1 1 0 1 1 1 0 LicD family LRR_5 PF13306.6 EAX93887.1 - 1e-96 319.7 61.6 1e-26 93.4 3.7 5.2 2 2 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93887.1 - 2.9e-11 42.9 0.0 0.011 15.5 0.0 7.8 6 3 1 7 7 7 3 Leucine rich repeat Phage-A118_gp45 PF10653.9 EAX93887.1 - 0.044 13.8 0.1 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 FNIP PF05725.12 EAX93887.1 - 9.3 6.5 22.6 15 5.8 0.2 7.5 6 1 1 8 8 8 0 FNIP Repeat BACK PF07707.15 EAX93888.1 - 0.025 14.7 1.0 0.053 13.6 1.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch CHASE9 PF17153.4 EAX93888.1 - 0.03 14.5 0.7 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular TGT PF01702.18 EAX93890.1 - 7.5e-107 357.5 0.0 9.4e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Steroid_dh PF02544.16 EAX93891.1 - 6.3e-20 71.7 6.5 6.3e-20 71.7 6.5 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EAX93891.1 - 0.0019 17.7 0.7 0.0019 17.7 0.7 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF1493 PF07377.12 EAX93892.1 - 0.07 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX93893.1 - 0.14 12.9 7.1 6.8 7.8 0.8 3.2 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX93893.1 - 5.7 6.9 8.3 6.2 6.8 8.3 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gly_rich PF12810.7 EAX93895.1 - 3.6e-51 174.4 31.9 4.6e-51 174.1 31.9 1.1 1 0 0 1 1 1 1 Glycine rich protein Ribosomal_S17_N PF16205.5 EAX93897.1 - 5.6e-28 97.1 0.5 9.6e-28 96.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAX93897.1 - 8.9e-27 93.0 0.8 1.7e-26 92.1 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 PCB_OB PF17092.5 EAX93897.1 - 0.017 15.8 0.0 0.031 15.0 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF5487 PF17589.2 EAX93897.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5487) OmdA PF13376.6 EAX93897.1 - 2.4 8.2 5.5 2.5 8.2 1.3 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated SHIPPO-rpt PF07004.12 EAX93898.1 - 0.00086 20.1 21.5 0.16 12.9 1.1 6.3 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat DUF1981 PF09324.10 EAX93899.1 - 0.0017 18.1 2.6 1.1 9.2 0.3 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1981) SHIPPO-rpt PF07004.12 EAX93901.1 - 8.1e-09 36.0 45.1 0.14 13.1 1.7 9.5 9 2 0 9 9 9 7 Sperm-tail PG-rich repeat Pkinase PF00069.25 EAX93902.1 - 1e-70 238.2 0.4 1.6e-70 237.5 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93902.1 - 3.5e-42 144.5 0.0 4.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX93902.1 - 8.4e-10 39.1 1.0 2e-09 37.9 1.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX93902.1 - 2e-06 27.3 0.0 4.9e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH_9 PF15410.6 EAX93902.1 - 0.00011 22.5 0.8 0.0053 17.1 0.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 EAX93902.1 - 0.024 13.6 0.5 0.039 12.9 0.5 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX93902.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1869 PF08956.10 EAX93902.1 - 0.039 13.9 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) FTA2 PF13095.6 EAX93902.1 - 0.12 12.0 0.8 2.3 7.8 0.1 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_5 PF13306.6 EAX93903.1 - 2.8e-96 318.3 124.5 4.5e-19 68.7 9.9 8.9 2 2 8 10 10 10 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93903.1 - 1.3e-09 37.7 7.3 4.1 7.2 0.0 10.7 7 2 4 12 12 12 2 Leucine rich repeat DUF2179 PF10035.9 EAX93903.1 - 0.0042 16.8 5.0 6.6 6.6 0.1 5.6 6 0 0 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2179) DUF347 PF03988.12 EAX93903.1 - 0.12 12.6 0.5 0.35 11.1 0.5 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Adeno_E3_CR2 PF02439.15 EAX93903.1 - 0.14 11.9 8.5 0.55 10.0 8.5 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GAGA_bind PF06217.12 EAX93904.1 - 0.027 14.8 4.8 0.032 14.5 4.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Rxt3 PF08642.10 EAX93904.1 - 0.99 10.2 4.2 1.5 9.6 4.2 1.4 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF3464 PF11947.8 EAX93904.1 - 5.4 6.7 8.0 9.5 6.0 8.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pox_A32 PF04665.12 EAX93905.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93905.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93905.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93905.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93905.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93905.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93905.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93905.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX93905.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93905.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93905.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93905.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX93906.1 - 1.4e-34 118.3 1.4 1.7e-34 118.0 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX93906.1 - 0.0043 17.7 0.0 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Ycf34 PF10718.9 EAX93906.1 - 0.17 12.6 2.2 4.2 8.1 0.2 3.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 LRR_5 PF13306.6 EAX93907.1 - 5.3e-114 375.6 106.4 2.7e-22 79.1 12.5 9.2 3 2 4 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX93907.1 - 3.9e-16 58.6 26.9 0.39 10.5 0.1 12.2 9 3 3 13 13 13 8 Leucine rich repeat Pet191_N PF10203.9 EAX93907.1 - 0.13 12.6 1.2 0.67 10.3 1.2 2.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 PPARgamma_N PF12577.8 EAX93907.1 - 0.18 12.5 6.2 1.7 9.3 0.0 4.6 3 1 1 4 4 4 0 PPAR gamma N-terminal region TMEM154 PF15102.6 EAX93908.1 - 0.047 13.6 0.5 0.058 13.3 0.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family T5orf172 PF10544.9 EAX93909.1 - 2.8e-07 31.0 0.3 5.7e-07 30.0 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAX93909.1 - 0.15 12.8 0.3 0.41 11.4 0.3 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 KilA-N PF04383.13 EAX93910.1 - 3.3e-41 139.6 0.4 7.3e-41 138.5 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX93910.1 - 0.013 16.1 0.1 0.036 14.7 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAX93911.1 - 6.9e-07 29.0 2.7 6.9e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93911.1 - 2.9e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93911.1 - 4.5e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93911.1 - 0.00015 21.8 3.2 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93911.1 - 0.00054 19.8 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93911.1 - 0.0015 18.3 0.8 0.0048 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93911.1 - 0.002 17.8 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93911.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX93911.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93911.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93911.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93911.1 - 0.42 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX93913.1 - 5.6e-62 207.9 7.3 6.3e-62 207.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3447 PF11929.8 EAX93914.1 - 4.8e-37 125.8 8.2 4.8e-37 125.8 8.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93914.1 - 9.3e-09 35.7 1.2 0.00035 21.1 0.7 3.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93914.1 - 3.7e-08 33.8 0.7 0.011 16.3 0.2 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX93914.1 - 1.8e-06 28.1 0.1 0.00018 21.7 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93914.1 - 0.00012 22.2 3.6 5.4 7.9 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EAX93914.1 - 0.0014 18.9 2.4 0.33 11.5 0.3 3.8 4 0 0 4 4 4 1 Ankyrin repeat RL PF17797.1 EAX93914.1 - 0.93 9.5 6.0 1.5 8.9 0.3 3.1 3 0 0 3 3 3 0 RL domain WD40 PF00400.32 EAX93915.1 - 2.1e-50 167.6 20.8 1.8e-09 38.1 0.1 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX93915.1 - 4e-23 81.5 3.6 3.1e-06 27.4 0.0 9.2 4 2 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EAX93915.1 - 1.6e-15 57.4 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 EAX93915.1 - 1.2e-08 35.0 0.9 0.018 14.9 0.1 4.4 4 0 0 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAX93915.1 - 6.2e-08 32.0 11.7 0.32 9.9 0.0 7.4 5 3 3 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EAX93915.1 - 7.5e-08 32.0 3.9 0.021 14.2 0.0 5.3 4 2 2 6 6 6 3 WD40-like domain Nup160 PF11715.8 EAX93915.1 - 3.1e-07 29.5 1.4 1.3 7.6 0.1 6.0 5 1 2 7 7 7 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAX93915.1 - 0.00049 19.0 0.8 1.6 7.4 0.0 4.2 4 1 0 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 EAX93915.1 - 0.0021 16.7 0.0 0.039 12.5 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain UTP15_C PF09384.10 EAX93915.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal PD40 PF07676.12 EAX93915.1 - 0.079 12.9 0.1 0.94 9.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ank_2 PF12796.7 EAX93916.1 - 1.6e-29 102.3 9.3 2.1e-11 44.3 0.2 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX93916.1 - 5.3e-24 84.0 1.6 5.3e-24 84.0 1.6 5.6 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX93916.1 - 3.8e-23 79.1 4.9 0.00049 20.3 0.0 7.8 7 1 1 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EAX93916.1 - 7.1e-23 80.7 4.4 5.7e-11 42.7 0.0 6.8 6 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX93916.1 - 1.3e-22 79.2 0.6 2.7e-06 27.6 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX93916.1 - 8e-14 51.5 0.3 1.5e-06 28.4 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PPR_2 PF13041.6 EAX93917.1 - 1.3e-12 47.7 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR_1 PF12854.7 EAX93917.1 - 1.7e-08 34.0 0.6 1.3e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 PPR repeat PPR PF01535.20 EAX93917.1 - 2.1e-08 33.9 0.5 0.00097 19.2 0.1 2.2 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 EAX93917.1 - 5.3e-08 32.8 0.1 6.8e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EAX93917.1 - 1e-05 25.0 0.2 1.2e-05 24.8 0.2 1.0 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 EAX93917.1 - 0.019 14.1 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Gly_rich PF12810.7 EAX93918.1 - 2.7e-21 76.6 22.2 3.1e-21 76.4 22.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Vps16_N PF04841.13 EAX93919.1 - 6.2e-25 87.8 0.0 9.7e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAX93919.1 - 0.0025 16.9 0.1 0.0044 16.1 0.1 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Connexin PF00029.19 EAX93920.1 - 0.001 18.9 0.5 0.0026 17.5 0.5 1.6 1 0 0 1 1 1 1 Connexin DUF4834 PF16118.5 EAX93920.1 - 0.0023 18.9 0.5 0.019 15.9 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Coilin_N PF15862.5 EAX93920.1 - 0.094 12.5 5.8 0.16 11.7 5.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus MAP17 PF15807.5 EAX93920.1 - 0.17 12.1 4.2 0.32 11.2 4.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 V_ATPase_I PF01496.19 EAX93920.1 - 0.48 8.3 5.9 0.034 12.1 0.8 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Zip PF02535.22 EAX93920.1 - 1.4 8.1 3.7 0.46 9.7 0.8 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 EAX93920.1 - 9.6 6.6 11.7 15 6.0 11.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myb_DNA-binding PF00249.31 EAX93921.1 - 4e-25 87.8 0.9 1.4e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93921.1 - 8.3e-17 61.2 0.0 6.2e-09 36.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX93921.1 - 1.2e-07 31.7 0.0 0.0044 17.0 0.0 2.3 2 0 0 2 2 2 2 SLIDE Tfb2_C PF18307.1 EAX93921.1 - 0.092 13.2 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain DNA_pol_B PF00136.21 EAX93922.1 - 5e-86 289.2 9.9 1.4e-60 205.4 8.6 2.4 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAX93922.1 - 1.1e-16 61.0 6.2 2.7e-16 59.7 6.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Ndc1_Nup PF09531.10 EAX93922.1 - 0.014 14.1 9.4 0.031 13.0 9.4 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_Tnp_IS1595 PF12760.7 EAX93922.1 - 0.02 14.9 0.9 0.049 13.6 0.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 EAX93922.1 - 0.73 10.2 4.6 48 4.4 4.6 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ank_2 PF12796.7 EAX93924.1 - 2.9e-53 178.4 23.0 3.3e-16 59.6 0.7 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93924.1 - 1.4e-49 165.9 20.5 1.6e-12 47.7 0.5 9.2 4 1 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX93924.1 - 2.3e-49 163.8 15.8 2.6e-08 33.9 0.2 8.5 8 0 0 8 8 8 7 Ankyrin repeat DUF3447 PF11929.8 EAX93924.1 - 2.8e-38 129.7 6.3 2.8e-38 129.7 6.3 5.6 3 1 2 6 6 6 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX93924.1 - 3.7e-36 119.0 16.1 7e-05 22.9 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX93924.1 - 3.5e-30 103.7 13.8 1.9e-11 44.0 0.9 6.9 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX93924.1 - 0.0046 16.7 2.1 0.25 11.1 0.0 3.8 2 1 2 4 4 4 1 Colon cancer-associated protein Mic1-like Arg_repressor PF01316.21 EAX93924.1 - 0.019 14.7 0.3 6.6 6.6 0.1 4.2 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain RNase_PH_C PF03725.15 EAX93924.1 - 0.05 13.6 0.9 33 4.6 0.0 3.9 3 1 1 4 4 4 0 3' exoribonuclease family, domain 2 TPR_MLP1_2 PF07926.12 EAX93925.1 - 0.0014 18.7 21.8 0.0014 18.7 21.8 12.0 2 2 9 12 12 12 7 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 EAX93925.1 - 0.0062 16.2 32.2 0.0062 16.2 32.2 8.9 3 3 5 8 8 8 4 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EAX93925.1 - 1.1 9.4 188.5 0.37 11.0 33.6 10.0 2 2 7 9 9 9 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAX93926.1 - 2.6e-05 23.3 55.1 0.00033 19.7 26.5 4.0 1 1 4 5 5 5 2 Spc7 kinetochore protein bZIP_1 PF00170.21 EAX93926.1 - 0.00012 22.2 44.9 0.054 13.6 1.5 6.5 6 0 0 6 6 6 4 bZIP transcription factor DivIC PF04977.15 EAX93926.1 - 0.0017 18.1 3.0 0.0017 18.1 3.0 6.4 5 1 0 6 6 6 4 Septum formation initiator Filament PF00038.21 EAX93926.1 - 0.0019 17.8 20.9 0.0019 17.8 20.9 3.1 1 1 1 2 2 2 1 Intermediate filament protein ATG16 PF08614.11 EAX93926.1 - 0.002 18.4 49.9 0.077 13.2 17.0 2.3 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EAX93926.1 - 0.021 14.8 7.0 0.021 14.8 7.0 6.5 4 2 2 6 6 5 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 EAX93926.1 - 0.023 14.9 8.8 0.023 14.9 8.8 6.6 2 1 4 6 6 6 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EAX93926.1 - 0.05 14.1 56.4 9.8 6.7 19.7 4.5 2 1 2 4 4 4 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 EAX93926.1 - 0.17 11.3 57.5 0.085 12.3 21.2 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EAX93926.1 - 0.79 9.0 33.1 0.23 10.8 15.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 EAX93926.1 - 1.9 5.9 50.9 1.1 6.7 48.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) YabA PF06156.13 EAX93926.1 - 2.2 8.9 50.9 0.92 10.2 5.4 5.5 1 1 4 5 5 5 0 Initiation control protein YabA DUF1515 PF07439.11 EAX93926.1 - 3.4 7.7 14.2 4.3 7.4 1.7 4.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) ApoO PF09769.9 EAX93926.1 - 5.5 7.0 17.4 0.064 13.2 1.2 4.0 2 2 0 2 2 2 0 Apolipoprotein O Fez1 PF06818.15 EAX93926.1 - 6 7.3 50.1 41 4.5 17.7 3.6 1 1 2 3 3 3 0 Fez1 HAP1_N PF04849.13 EAX93926.1 - 8.2 5.5 54.5 9.8 5.3 27.3 3.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GPS2_interact PF15784.5 EAX93927.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX93927.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX93929.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX93930.1 - 0.048 14.1 0.9 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Ribosomal_L27e PF01777.18 EAX93930.1 - 1.6 9.1 12.5 0.59 10.5 5.5 2.2 1 1 1 2 2 2 0 Ribosomal L27e protein family PapD_N PF00345.20 EAX93931.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX93931.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_pol_B_2 PF03175.13 EAX93932.1 - 9.4e-31 107.2 13.6 4.1e-30 105.1 13.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Fic PF02661.18 EAX93933.1 - 0.02 15.8 0.0 0.04 14.8 0.0 1.5 1 0 0 1 1 1 0 Fic/DOC family DUF4106 PF13388.6 EAX93934.1 - 4.2e-21 75.7 3.4 4.2e-21 75.7 3.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF885 PF05960.11 EAX93934.1 - 0.0064 16.2 1.6 0.0071 16.0 1.6 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF3452 PF11934.8 EAX93934.1 - 0.091 12.3 1.7 0.15 11.6 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) FapA PF03961.13 EAX93934.1 - 0.4 9.2 5.8 0.47 9.0 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EAX93934.1 - 1.9 8.5 4.6 0.5 10.3 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Pkinase PF00069.25 EAX93935.1 - 4.1e-68 229.6 0.0 4.9e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX93935.1 - 3.4e-32 111.8 0.0 4.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX93935.1 - 0.00038 19.9 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX93935.1 - 0.00064 19.1 0.0 0.053 12.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX93935.1 - 0.005 15.8 0.3 0.009 15.0 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX93935.1 - 0.011 14.6 0.0 0.064 12.0 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 EAX93935.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EAX93935.1 - 0.032 14.2 0.1 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PMC2NT PF08066.12 EAX93936.1 - 0.013 16.2 0.1 0.056 14.1 0.1 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Thioredoxin PF00085.20 EAX93936.1 - 0.03 14.3 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin Ank_2 PF12796.7 EAX93937.1 - 3.2e-56 187.9 11.2 2.1e-18 66.7 0.2 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93937.1 - 2e-40 132.2 7.9 7e-06 26.0 0.0 9.2 9 1 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 EAX93937.1 - 5.1e-39 131.1 4.9 1.5e-05 25.3 0.1 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EAX93937.1 - 2.2e-36 123.8 5.2 1.6e-06 28.5 0.0 6.3 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93937.1 - 4.6e-30 103.3 6.8 1.4e-08 34.8 0.1 7.4 3 2 5 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93937.1 - 8.5e-10 38.5 1.6 8.5e-10 38.5 1.6 4.2 3 1 3 6 6 6 1 Domain of unknown function (DUF3447) VWA_3_C PF18571.1 EAX93937.1 - 0.07 13.0 0.1 6.4 6.7 0.0 2.9 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 EAX93938.1 - 6.3e-57 190.1 9.5 6e-17 62.0 0.0 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93938.1 - 5.9e-26 90.5 0.1 2e-07 31.4 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93938.1 - 1e-24 86.3 0.4 5.5e-07 29.7 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX93938.1 - 3.1e-24 84.3 0.4 0.00041 20.7 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX93938.1 - 5.9e-23 78.5 0.0 0.015 15.8 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAX93939.1 - 4.2e-13 49.1 1.1 1.6e-07 31.4 0.2 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX93939.1 - 1.3e-11 44.8 0.1 1.7e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX93939.1 - 1e-10 42.0 1.1 2.1e-10 41.1 1.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93939.1 - 4.1e-10 39.0 0.1 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX93939.1 - 2.6e-05 24.4 0.0 4.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Sec23_trunk PF04811.15 EAX93940.1 - 2.9e-23 82.7 0.0 4.7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAX93940.1 - 1.7e-13 51.1 0.0 4.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EAX93940.1 - 1.5e-05 25.0 9.7 3.1e-05 23.9 9.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger TUG-UBL1 PF11470.8 EAX93940.1 - 0.012 15.8 0.0 0.047 13.9 0.0 2.0 1 0 0 1 1 1 0 TUG ubiquitin-like domain ubiquitin PF00240.23 EAX93940.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family PARP PF00644.20 EAX93942.1 - 3e-15 56.3 0.2 5.9e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EAX93942.1 - 7.1e-06 26.2 0.1 0.0045 17.2 0.0 3.3 2 1 1 3 3 3 2 ARTD15 N-terminal domain UBA PF00627.31 EAX93942.1 - 2.9e-05 23.9 0.6 2.9e-05 23.9 0.6 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 EAX93942.1 - 0.024 14.5 0.2 0.024 14.5 0.2 1.9 2 0 0 2 2 2 0 UBA-like domain RuvA_C PF07499.13 EAX93942.1 - 0.056 13.9 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 RuvA, C-terminal domain Ank_2 PF12796.7 EAX93943.1 - 9.8e-61 202.3 13.2 1.8e-14 54.1 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93943.1 - 1.9e-30 104.8 0.0 1.5e-08 35.0 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93943.1 - 3.8e-25 85.2 1.3 0.00015 21.9 0.0 7.1 7 0 0 7 7 6 6 Ankyrin repeat Ank_5 PF13857.6 EAX93943.1 - 1.7e-22 79.2 2.9 1.4e-09 38.1 0.1 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX93943.1 - 1.7e-21 75.6 0.1 0.0036 17.7 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat DUF4200 PF13863.6 EAX93943.1 - 0.0024 18.3 1.2 0.0046 17.4 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) ADIP PF11559.8 EAX93943.1 - 0.0053 16.9 1.3 0.011 15.9 1.3 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3287 PF11690.8 EAX93943.1 - 0.014 15.1 0.2 0.033 13.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Tup_N PF08581.10 EAX93943.1 - 0.017 15.4 1.4 7.8 6.9 1.6 2.7 1 1 0 2 2 2 0 Tup N-terminal DUF4618 PF15397.6 EAX93943.1 - 0.019 14.4 1.2 0.033 13.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1110 PF06533.12 EAX93943.1 - 0.12 12.4 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) Cnd1 PF12717.7 EAX93943.1 - 1.4 8.9 5.9 0.97 9.5 1.7 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TSC22 PF01166.18 EAX93943.1 - 2.9 8.3 5.1 1.5 9.2 0.7 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Macro PF01661.21 EAX93944.1 - 2.7e-31 108.1 0.3 5.5e-31 107.1 0.3 1.6 1 0 0 1 1 1 1 Macro domain Paf1 PF03985.13 EAX93944.1 - 7.1e-05 22.0 6.4 7.1e-05 22.0 6.4 2.1 2 0 0 2 2 2 1 Paf1 CCDC53 PF10152.9 EAX93944.1 - 0.028 14.9 0.4 0.028 14.9 0.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DDHD PF02862.17 EAX93944.1 - 0.51 10.5 7.0 1.3 9.1 0.9 2.1 2 0 0 2 2 2 0 DDHD domain DUF2052 PF09747.9 EAX93944.1 - 1.6 8.9 33.6 0.69 10.0 12.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 EAX93944.1 - 2.4 7.4 28.6 0.39 10.0 10.3 2.1 2 0 0 2 2 2 0 BUD22 CPSF100_C PF13299.6 EAX93944.1 - 2.7 8.1 21.2 0.66 10.1 7.8 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EAX93944.1 - 3.9 6.1 16.7 0.32 9.7 4.5 2.1 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 EAX93944.1 - 5 6.2 11.3 2.1 7.5 2.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 EAX93944.1 - 6.8 6.4 31.4 2.4 7.9 13.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SpoIIIAH PF12685.7 EAX93944.1 - 7.4 6.3 19.2 0.85 9.4 6.8 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 EAX93944.1 - 8.1 6.9 21.1 0.54 10.7 7.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Neur_chan_memb PF02932.16 EAX93944.1 - 9.3 6.2 6.3 4.4 7.3 0.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ank_4 PF13637.6 EAX93945.1 - 1.8e-96 315.3 30.8 3.2e-12 46.7 0.2 13.3 3 1 11 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 EAX93945.1 - 2.6e-91 296.4 26.0 4.3e-10 39.6 0.4 13.7 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.7 EAX93945.1 - 3.2e-83 274.4 43.8 5.2e-18 65.4 4.2 8.7 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93945.1 - 2e-68 218.2 31.2 1.2e-06 28.3 0.1 14.5 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 EAX93945.1 - 3.4e-66 218.4 25.7 1.4e-09 38.0 0.1 9.2 4 3 6 10 10 10 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX93945.1 - 1.4e-36 124.3 7.2 1.4e-36 124.3 7.2 5.5 5 2 2 7 7 7 1 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAX93945.1 - 0.0016 18.2 19.0 0.044 13.4 1.4 3.3 1 1 2 3 3 3 3 Coiled coil protein 84 RNase_PH_C PF03725.15 EAX93945.1 - 0.0048 16.9 2.9 3.7 7.7 0.0 5.4 4 2 1 5 5 5 1 3' exoribonuclease family, domain 2 HEM4 PF02602.15 EAX93945.1 - 0.15 11.4 0.3 7.2 5.9 0.0 3.1 4 1 0 4 4 4 0 Uroporphyrinogen-III synthase HemD PrmC_N PF17827.1 EAX93945.1 - 0.15 12.6 0.2 48 4.6 0.0 3.6 4 0 0 4 4 4 0 PrmC N-terminal domain DUF2149 PF09919.9 EAX93945.1 - 1.6 9.1 6.9 13 6.1 0.0 4.6 6 0 0 6 6 6 0 Uncharacterized conserved protein (DUF2149) PhoU PF01895.19 EAX93946.1 - 0.42 11.1 2.3 8.2 7.0 0.1 3.3 3 0 0 3 3 3 0 PhoU domain Ank_2 PF12796.7 EAX93947.1 - 8.2e-58 193.0 9.0 4.9e-17 62.3 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) LRR_5 PF13306.6 EAX93947.1 - 1.1e-46 157.9 15.2 3.7e-26 91.6 1.5 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Ank_4 PF13637.6 EAX93947.1 - 1.4e-29 102.0 0.0 3.5e-08 33.8 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93947.1 - 1.3e-22 77.4 0.8 0.00022 21.4 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX93947.1 - 2.9e-21 75.2 3.7 2e-09 37.5 0.1 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX93947.1 - 8.5e-20 70.3 0.2 0.0051 17.2 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat LRR_8 PF13855.6 EAX93947.1 - 8.3e-06 25.5 0.0 0.18 11.6 0.0 3.9 3 1 1 4 4 4 3 Leucine rich repeat DUF3839 PF12943.7 EAX93950.1 - 5.2e-157 520.5 13.2 6.6e-157 520.2 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX93950.1 - 0.068 13.0 1.3 0.23 11.3 0.6 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX93950.1 - 1.2 9.6 4.5 7.3 7.1 0.2 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Thioredoxin PF00085.20 EAX93951.1 - 4e-05 23.5 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAX93951.1 - 4.3e-05 23.0 0.1 8.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 EAX93951.1 - 0.094 13.1 0.0 0.6 10.6 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Bromodomain PF00439.25 EAX93952.1 - 7.1e-19 67.7 0.4 1e-18 67.2 0.4 1.2 1 0 0 1 1 1 1 Bromodomain Sipho_Gp157 PF05565.11 EAX93952.1 - 0.033 14.2 1.7 0.053 13.5 1.7 1.3 1 1 0 1 1 1 0 Siphovirus Gp157 FdsD PF11390.8 EAX93952.1 - 0.13 12.6 0.1 14 6.1 0.1 2.6 1 1 2 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF1421 PF07223.11 EAX93952.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) MULE PF10551.9 EAX93953.1 - 2.9e-07 30.8 1.0 4.8e-07 30.1 1.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX93953.1 - 0.00083 18.3 0.3 0.0011 17.9 0.3 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Adaptin_binding PF10199.9 EAX93954.1 - 0.16 12.6 2.9 0.47 11.1 2.8 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF4107 PF13389.6 EAX93957.1 - 2.5e-70 235.8 3.6 3.8e-70 235.2 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX93958.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase GPS2_interact PF15784.5 EAX93961.1 - 0.33 11.4 3.7 0.44 11.0 3.7 1.3 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3781 PF12636.7 EAX93962.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3839 PF12943.7 EAX93963.1 - 2.7e-152 505.1 12.4 3.3e-152 504.8 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) HAP1_N PF04849.13 EAX93963.1 - 0.017 14.4 0.0 0.15 11.2 0.0 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Glu-tRNAGln PF02686.15 EAX93963.1 - 0.09 13.1 1.6 0.16 12.3 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Rx_N PF18052.1 EAX93963.1 - 0.37 11.1 2.2 40 4.6 0.1 3.5 4 1 0 4 4 4 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX93964.1 - 5.6e-07 29.3 2.3 5.6e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX93964.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX93964.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX93964.1 - 0.00015 21.9 3.2 0.00031 20.8 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX93964.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX93964.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX93964.1 - 0.0018 17.9 0.4 0.01 15.5 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX93964.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX93964.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX93964.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX93964.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX93964.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PRA-PH PF01503.17 EAX93966.1 - 0.23 11.9 2.2 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Consortin_C PF15281.6 EAX93967.1 - 0.24 11.4 6.3 8.5 6.4 0.1 3.2 2 1 1 3 3 3 0 Consortin C-terminus YvrJ PF12841.7 EAX93967.1 - 0.25 10.9 1.6 1.1 8.8 0.8 2.3 2 0 0 2 2 2 0 YvrJ protein family DUF4472 PF14739.6 EAX93967.1 - 0.48 11.2 2.5 0.43 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Ras PF00071.22 EAX93968.1 - 3e-47 160.2 1.9 3.6e-47 160.0 1.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX93968.1 - 8.9e-32 109.8 0.2 1.5e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX93968.1 - 1.7e-15 56.9 0.1 2.3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX93968.1 - 8.6e-07 29.0 0.2 2.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX93968.1 - 4.3e-05 23.5 0.5 0.019 14.9 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EAX93968.1 - 0.00013 21.6 0.1 0.00085 18.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX93968.1 - 0.00053 19.5 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX93968.1 - 0.00057 19.3 0.3 0.00067 19.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX93968.1 - 0.036 13.8 1.4 0.47 10.2 0.6 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EAX93968.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EAX93968.1 - 0.057 13.0 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 EAX93968.1 - 0.065 12.7 0.4 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Ntox47 PF15540.6 EAX93968.1 - 0.096 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 47 DUF3284 PF11687.8 EAX93968.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) Myb_DNA-binding PF00249.31 EAX93969.1 - 1.2e-23 83.0 1.8 3.1e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX93969.1 - 3.6e-20 72.0 6.0 5.8e-11 42.5 0.8 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX93969.1 - 7.7e-05 22.5 0.1 0.00018 21.4 0.1 1.7 1 1 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX93969.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX93969.1 - 0.47 10.9 5.0 4.5 7.7 0.7 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Profilin PF00235.19 EAX93970.1 - 3.9e-20 72.4 0.1 4.5e-20 72.2 0.1 1.0 1 0 0 1 1 1 1 Profilin SapB_1 PF05184.15 EAX93970.1 - 0.05 13.6 1.5 0.05 13.6 1.5 1.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 B56 PF01603.20 EAX93971.1 - 5.7e-42 144.1 17.0 5.7e-42 144.1 17.0 1.5 1 1 1 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Ank_2 PF12796.7 EAX93972.1 - 3.1e-07 30.9 0.4 0.00069 20.2 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX93972.1 - 1.3e-05 25.2 0.2 0.18 12.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAX93972.1 - 3.1e-05 23.8 2.0 3.1e-05 23.8 2.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX93972.1 - 0.00032 21.2 0.1 0.27 11.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX93972.1 - 0.0097 16.3 0.0 0.56 10.7 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeat DUF4795 PF16043.5 EAX93973.1 - 0.00079 19.1 18.3 0.011 15.3 4.3 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) Peptidase_M41 PF01434.18 EAX93973.1 - 0.061 13.2 4.0 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Peptidase family M41 GST_C PF00043.25 EAX93973.1 - 0.091 13.0 3.4 16 5.8 0.1 3.3 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF305 PF03713.13 EAX93973.1 - 0.15 12.2 1.2 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF305) AlkA_N PF06029.11 EAX93973.1 - 0.21 11.8 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 AlkA N-terminal domain DUF2120 PF09893.9 EAX93973.1 - 0.42 10.7 9.4 2.8 8.0 1.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Urocanase PF01175.18 EAX93973.1 - 1 9.0 3.3 22 4.6 0.5 2.4 2 1 0 2 2 2 0 Urocanase Rossmann-like domain Spherulin4 PF12138.8 EAX93973.1 - 1.9 8.1 8.4 1.2e+02 2.2 8.3 2.2 1 1 0 1 1 1 0 Spherulation-specific family 4 DUF4508 PF14969.6 EAX93973.1 - 2.1 8.7 7.8 27 5.1 0.4 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4508) Peptidase_U57 PF05582.12 EAX93973.1 - 4.5 6.4 6.9 8.7 5.5 2.5 2.1 1 1 1 2 2 2 0 YabG peptidase U57 ARA70 PF12489.8 EAX93974.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator UPF0146 PF03686.13 EAX93975.1 - 0.0014 18.5 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Rax2 PF12768.7 EAX93975.1 - 0.0028 17.2 0.4 0.0065 15.9 0.4 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.12 EAX93975.1 - 0.0031 17.4 0.7 0.0068 16.2 0.7 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAX93975.1 - 0.0036 17.2 4.3 0.01 15.8 4.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 EAX93975.1 - 0.0052 17.1 0.8 0.013 15.8 0.8 1.7 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 EAX93975.1 - 0.0059 16.5 3.6 0.0059 16.5 3.6 1.7 2 0 0 2 2 2 1 Rifin PIRT PF15099.6 EAX93975.1 - 0.0079 15.8 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family DUF4064 PF13273.6 EAX93975.1 - 0.018 15.3 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4448 PF14610.6 EAX93975.1 - 0.026 14.3 0.4 0.026 14.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.6 EAX93975.1 - 0.03 14.6 0.3 0.052 13.8 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 EAX93975.1 - 0.039 13.9 1.6 0.094 12.6 1.6 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 EAX93975.1 - 0.068 14.1 0.8 0.23 12.3 0.3 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 EAX93975.1 - 0.096 13.4 0.2 0.31 11.8 0.2 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4519 PF15012.6 EAX93975.1 - 0.12 12.6 1.1 0.39 10.9 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ly49 PF08391.10 EAX93975.1 - 0.14 12.6 1.3 0.34 11.3 0.5 2.2 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region Baculo_11_kDa PF06143.11 EAX93975.1 - 0.16 11.6 1.6 0.37 10.4 1.6 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Y_Y_Y PF07495.13 EAX93975.1 - 0.17 11.9 6.1 63 3.6 0.0 4.5 4 0 0 4 4 4 0 Y_Y_Y domain UPF0239 PF06783.11 EAX93975.1 - 2.7 8.2 7.0 2.5 8.3 0.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) Peptidase_M48 PF01435.18 EAX93976.1 - 2.4e-24 86.2 0.0 4.4e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EAX93976.1 - 0.014 14.6 4.6 0.18 11.0 4.6 2.2 1 1 0 1 1 1 0 BlaR1 peptidase M56 TIG PF01833.24 EAX93977.1 - 4.5e-07 29.9 0.5 7.2e-07 29.2 0.5 1.3 1 0 0 1 1 1 1 IPT/TIG domain DUF2207 PF09972.9 EAX93977.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TIG_plexin PF17960.1 EAX93977.1 - 0.017 15.1 1.2 0.069 13.2 1.2 1.9 1 1 0 1 1 1 0 TIG domain TERT_thumb PF17984.1 EAX93977.1 - 0.063 13.2 0.2 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain Flp1_like PF16982.5 EAX93977.1 - 0.26 10.7 6.9 0.052 13.0 3.4 1.6 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Endosulfine PF04667.17 EAX93978.1 - 0.074 13.2 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3781 PF12636.7 EAX93980.1 - 0.039 13.8 0.8 0.062 13.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) FAS_N PF17828.1 EAX93981.1 - 0.0099 15.9 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4107 PF13389.6 EAX93984.1 - 3.1e-32 112.0 2.7 4.4e-32 111.5 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX93984.1 - 0.064 11.7 0.5 0.066 11.6 0.5 1.0 1 0 0 1 1 1 0 Lipoxygenase DUF3781 PF12636.7 EAX93985.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Ank_2 PF12796.7 EAX93988.1 - 9e-40 135.1 4.8 1.8e-13 50.9 0.1 7.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX93988.1 - 4.3e-38 129.2 7.9 6.3e-11 42.6 0.0 8.7 7 1 2 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX93988.1 - 3.4e-29 100.5 4.3 5.3e-10 39.3 0.0 7.0 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX93988.1 - 1.1e-26 89.9 13.6 0.00021 21.5 0.0 12.2 13 1 0 13 13 13 4 Ankyrin repeat Ank PF00023.30 EAX93988.1 - 8e-22 76.7 0.9 2.6e-05 24.5 0.0 8.8 9 1 0 9 9 9 3 Ankyrin repeat DUF3447 PF11929.8 EAX93988.1 - 1.5e-07 31.3 1.2 1.5e-07 31.3 1.2 4.7 4 2 0 4 4 4 1 Domain of unknown function (DUF3447) CCDC53 PF10152.9 EAX93990.1 - 0.00047 20.6 0.9 0.00067 20.1 0.9 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex CTP_transf_3 PF02348.19 EAX93990.1 - 0.0054 16.7 0.5 0.0081 16.1 0.5 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF3791 PF12668.7 EAX93990.1 - 0.02 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) UCH PF00443.29 EAX93991.1 - 1.1e-15 57.8 0.4 1.1e-15 57.8 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX93991.1 - 5.7e-05 22.9 0.5 9e-05 22.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tenui_NCP PF04876.12 EAX93991.1 - 0.098 12.2 0.4 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein C2 PF00168.30 EAX93992.1 - 1.7e-11 44.4 0.0 2.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF5623 PF18536.1 EAX93993.1 - 0.082 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX93993.1 - 0.42 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4107 PF13389.6 EAX93995.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1390 PF07150.11 EAX93996.1 - 0.07 12.8 0.2 0.091 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) GvpL_GvpF PF06386.11 EAX93998.1 - 0.032 14.2 0.2 0.055 13.4 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF rve PF00665.26 EAX93999.1 - 2.4e-20 72.9 0.0 3.6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EAX93999.1 - 9.3e-08 32.4 0.2 5.7e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.6 EAX93999.1 - 1.2e-05 25.0 0.8 0.00012 21.8 0.5 2.7 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_1 PF01609.21 EAX93999.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Transposase DDE domain WD40 PF00400.32 EAX94000.1 - 5.5e-37 125.1 10.0 2.6e-08 34.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94000.1 - 5.3e-19 68.3 0.6 0.0039 17.5 0.1 5.7 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EAX94000.1 - 7.5e-13 48.8 0.1 1.4e-12 48.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain TFIIIC_delta PF12657.7 EAX94000.1 - 5e-06 26.6 1.0 0.0028 17.6 0.0 3.1 3 1 0 3 3 3 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 EAX94000.1 - 6.7e-06 25.3 0.0 0.015 14.2 0.0 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2140 PF09911.9 EAX94000.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) Frtz PF11768.8 EAX94000.1 - 0.0027 16.1 0.0 0.21 9.9 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 EAX94000.1 - 0.0061 15.7 0.1 0.33 9.9 0.3 2.5 1 1 1 3 3 3 1 Coatomer WD associated region IKI3 PF04762.12 EAX94000.1 - 0.011 13.8 0.1 0.36 8.8 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PQQ_2 PF13360.6 EAX94000.1 - 0.035 13.7 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 EAX94000.1 - 0.052 12.2 0.1 10 4.6 0.0 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EAX94000.1 - 0.063 12.6 0.1 17 4.6 0.0 3.8 6 0 0 6 6 6 0 WD40-like domain PQQ PF01011.21 EAX94000.1 - 0.095 12.7 0.0 3.4 7.7 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Ribosomal_S30 PF04758.14 EAX94001.1 - 9.6e-26 89.8 3.2 1.1e-25 89.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ank_2 PF12796.7 EAX94002.1 - 9.9e-05 22.9 0.1 0.0068 17.0 0.0 2.5 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94002.1 - 0.00085 19.6 0.2 3.4 8.5 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EAX94002.1 - 0.07 13.7 0.4 24 5.7 0.0 3.8 2 2 0 3 3 3 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94002.1 - 5.3 7.1 21.3 0.14 12.1 9.3 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) DDE_1 PF03184.19 EAX94003.1 - 7.9e-09 35.4 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 EAX94005.1 - 4.4e-13 49.5 9.6 6.2e-05 23.7 0.2 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94005.1 - 2.3e-08 34.2 2.1 0.0008 19.7 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EAX94005.1 - 0.0071 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 EAX94005.1 - 0.04 13.8 0.1 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ribosomal_S27e PF01667.17 EAX94007.1 - 2.8e-15 55.8 0.3 3.6e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DZR PF12773.7 EAX94007.1 - 0.05 13.6 2.0 0.77 9.8 2.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon Meiosis_expr PF15163.6 EAX94008.1 - 0.058 14.1 0.9 0.082 13.6 0.4 1.5 2 0 0 2 2 2 0 Meiosis-expressed Gly_rich PF12810.7 EAX94010.1 - 4e-15 56.4 38.8 5.5e-15 55.9 38.8 1.2 1 0 0 1 1 1 1 Glycine rich protein Furin-like_2 PF15913.5 EAX94010.1 - 0.042 14.0 50.2 0.025 14.8 18.6 3.7 2 1 2 4 4 4 0 Furin-like repeat, cysteine-rich Shisa PF13908.6 EAX94011.1 - 0.00054 20.3 1.0 0.00092 19.5 1.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF960 PF06124.11 EAX94011.1 - 0.044 14.4 1.9 1.4 9.6 0.3 3.0 2 2 1 3 3 3 0 Staphylococcal protein of unknown function (DUF960) Helicase_C PF00271.31 EAX94011.1 - 0.14 12.5 0.2 0.31 11.4 0.2 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Orthoreo_P10 PF07204.11 EAX94011.1 - 0.31 11.0 3.6 0.66 10.0 3.6 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF4713 PF15831.5 EAX94011.1 - 5.9 7.4 12.6 11 6.6 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) LRR_5 PF13306.6 EAX94012.1 - 1.5e-131 432.3 212.7 5.2e-19 68.5 11.2 11.7 2 2 10 12 12 12 12 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94012.1 - 3.9e-23 81.0 21.0 0.00037 20.2 0.0 12.5 13 1 2 15 15 15 8 Leucine rich repeat LRR_4 PF12799.7 EAX94012.1 - 0.0032 17.9 26.7 7.9 7.1 0.1 10.9 7 3 3 10 10 10 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94013.1 - 3.7e-44 149.8 74.4 1.4e-18 67.1 15.9 4.3 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX94014.1 - 1e-83 277.7 94.5 1.4e-28 99.4 15.1 5.3 1 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94014.1 - 4.8e-19 67.9 6.9 0.0019 17.9 0.0 8.6 5 2 5 10 10 10 7 Leucine rich repeat DUF1699 PF08004.11 EAX94014.1 - 0.0043 16.7 0.8 5.8 6.6 0.0 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1699) Spidroin_MaSp PF11260.8 EAX94014.1 - 0.076 13.3 0.1 0.63 10.4 0.0 2.3 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Romo1 PF10247.9 EAX94015.1 - 0.035 14.5 0.7 3.3 8.1 1.3 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Fib_alpha PF08702.10 EAX94015.1 - 0.48 10.6 2.3 0.53 10.5 0.8 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF373 PF04123.13 EAX94015.1 - 1.2 8.5 16.5 0.21 11.0 12.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) TMEMspv1-c74-12 PF11044.8 EAX94015.1 - 2.4 8.2 5.4 12 6.0 5.4 2.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Guanylate_cyc PF00211.20 EAX94016.1 - 3.4e-44 150.7 0.1 7e-44 149.6 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX94016.1 - 4.6e-06 26.8 0.2 1.2e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX94016.1 - 0.00035 20.6 0.0 0.00087 19.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAX94016.1 - 0.002 18.1 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain TMEM171 PF15471.6 EAX94016.1 - 0.054 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Pho88 PF10032.9 EAX94016.1 - 0.073 12.3 2.0 0.19 11.0 2.0 1.6 1 0 0 1 1 1 0 Phosphate transport (Pho88) PAS_4 PF08448.10 EAX94016.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold EamA PF00892.20 EAX94016.1 - 0.89 9.7 4.2 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 EamA-like transporter family Fungal_trans_2 PF11951.8 EAX94016.1 - 1.6 7.4 4.7 3.8 6.2 4.7 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain Vpu PF00558.19 EAX94016.1 - 7.3 6.4 7.6 1.6 8.6 3.0 2.3 2 0 0 2 2 2 0 Vpu protein DHHC PF01529.20 EAX94017.1 - 3e-09 37.1 7.3 4.1e-09 36.6 7.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ac76 PF05814.11 EAX94017.1 - 5.5e-05 23.1 1.0 9.2e-05 22.4 1.0 1.4 1 0 0 1 1 1 1 Orf76 (Ac76) DUF2862 PF11061.8 EAX94017.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Pkinase PF00069.25 EAX94019.1 - 4.3e-51 173.8 1.3 7e-51 173.1 1.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94019.1 - 3e-40 138.1 0.8 4.1e-40 137.7 0.8 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX94019.1 - 0.00047 19.0 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX94019.1 - 0.005 16.2 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX94019.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX94019.1 - 0.027 14.1 0.1 0.067 12.8 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAX94019.1 - 0.048 13.2 2.8 0.25 10.9 0.7 2.5 2 1 1 3 3 3 0 RIO1 family Kinase-like PF14531.6 EAX94019.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like GPS2_interact PF15784.5 EAX94021.1 - 0.036 14.5 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FAS_N PF17828.1 EAX94023.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX94024.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94024.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX94025.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Pox_A32 PF04665.12 EAX94026.1 - 1.5e-07 31.1 2.7 2.1e-07 30.7 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX94026.1 - 0.0031 17.2 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX94026.1 - 0.055 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX94026.1 - 0.058 13.1 0.2 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX94026.1 - 0.084 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2666 PF10869.8 EAX94026.1 - 0.52 10.5 8.3 5.7 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) Mito_fiss_reg PF05308.11 EAX94027.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX94027.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PTR PF12789.7 EAX94029.1 - 1.4e-49 165.9 30.8 6.9e-33 112.5 15.0 5.1 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX94029.1 - 0.039 13.7 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX94031.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX94032.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Metallophos PF00149.28 EAX94033.1 - 1.5e-17 64.8 0.0 2.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GARS_N PF02844.15 EAX94033.1 - 0.1 13.4 0.0 0.5 11.2 0.0 2.2 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain SHIPPO-rpt PF07004.12 EAX94034.1 - 3.9e-07 30.7 28.3 0.3 12.1 0.2 6.5 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat DUF1933 PF09147.10 EAX94034.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) DUF641 PF04859.12 EAX94035.1 - 0.0073 16.6 2.8 0.0073 16.6 2.8 11.5 6 4 5 12 12 12 2 Plant protein of unknown function (DUF641) Myb_DNA-binding PF00249.31 EAX94036.1 - 5.9e-24 84.0 0.8 1.7e-07 31.3 0.1 4.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94036.1 - 7e-21 74.2 19.1 9e-11 41.9 0.3 5.5 5 0 0 5 5 5 3 Myb-like DNA-binding domain UBA PF00627.31 EAX94036.1 - 0.0059 16.5 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Sigma70_r4_2 PF08281.12 EAX94036.1 - 0.016 14.9 0.2 0.051 13.3 0.2 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 Mcp5_PH PF12814.7 EAX94036.1 - 0.037 14.1 2.7 0.11 12.6 2.7 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Phage_antitermQ PF06530.12 EAX94036.1 - 0.039 13.9 0.9 0.21 11.5 0.5 2.5 2 0 0 2 2 2 0 Phage antitermination protein Q DUF563 PF04577.14 EAX94037.1 - 1.8e-23 83.8 2.1 2.7e-23 83.2 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) NAGidase PF07555.13 EAX94037.1 - 0.067 12.5 1.1 0.14 11.5 1.1 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF563 PF04577.14 EAX94038.1 - 2.6e-09 37.5 0.0 4.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_transf_17 PF04724.13 EAX94039.1 - 1.6e-20 73.5 2.2 3.5e-20 72.4 2.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF4108 PF13390.6 EAX94040.1 - 3.2e-55 186.0 7.4 3.6e-55 185.8 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3464 PF11947.8 EAX94041.1 - 1.2 8.9 3.2 1.3 8.8 2.5 1.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2897 PF11446.8 EAX94041.1 - 1.4 8.9 4.7 2.7 7.9 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX94042.1 - 8.1e-07 28.8 2.3 8.1e-07 28.8 2.3 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX94042.1 - 5.6e-05 23.4 0.2 0.00036 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX94042.1 - 0.00023 21.2 3.2 0.00053 20.0 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX94042.1 - 0.00025 20.8 0.2 0.42 10.3 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX94042.1 - 0.00089 19.1 0.1 0.0016 18.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX94042.1 - 0.0021 17.9 0.5 0.0043 16.9 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX94042.1 - 0.0032 17.2 0.5 0.017 14.8 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX94042.1 - 0.017 15.5 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX94042.1 - 0.1 12.2 0.0 0.33 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX94043.1 - 6e-80 268.2 11.2 7.9e-80 267.8 11.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX94043.1 - 0.089 12.3 0.4 0.3 10.6 0.1 2.0 2 1 0 2 2 2 0 SLOG cluster2 Adaptin_N PF01602.20 EAX94044.1 - 2.3e-23 82.5 4.8 3.5e-23 82.0 4.8 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EAX94044.1 - 2.3e-09 37.5 3.7 0.0024 18.2 0.0 4.8 4 2 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EAX94044.1 - 8.9e-09 35.6 0.4 0.0066 16.5 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX94044.1 - 5.6e-07 29.3 1.5 0.97 9.9 0.0 5.2 5 0 0 5 5 4 2 HEAT repeat HEAT_EZ PF13513.6 EAX94044.1 - 8.7e-05 22.9 0.3 8.1 7.1 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat RIX1 PF08167.12 EAX94044.1 - 0.0018 18.0 1.9 0.83 9.4 0.5 3.6 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EAX94044.1 - 0.011 15.9 1.8 0.58 10.3 0.1 3.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Coatamer_beta_C PF07718.12 EAX94044.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta C-terminal region RTP1_C2 PF10304.9 EAX94044.1 - 0.015 14.9 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 API5 PF05918.11 EAX94044.1 - 0.034 13.0 0.3 0.064 12.1 0.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Vac14_Fab1_bd PF12755.7 EAX94044.1 - 0.041 14.5 0.2 5.6 7.6 0.0 2.9 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 EAX94044.1 - 0.095 13.4 0.3 1.4 9.8 0.0 3.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat zf-C3HC4_2 PF13923.6 EAX94045.1 - 9.8e-13 47.7 8.9 1.6e-12 47.1 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX94045.1 - 2.9e-11 43.5 10.9 4.5e-11 42.9 10.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX94045.1 - 7.9e-11 41.7 10.6 1.3e-10 40.9 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAX94045.1 - 2.4e-09 36.9 11.4 3.6e-09 36.3 11.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX94045.1 - 8e-09 35.4 5.4 1.6e-08 34.4 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAX94045.1 - 9.3e-08 31.8 12.2 1.4e-07 31.2 12.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAX94045.1 - 8.8e-07 29.1 11.5 9.9e-06 25.8 11.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAX94045.1 - 5.9e-06 26.1 14.2 9.2e-06 25.5 14.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAX94045.1 - 6.1e-05 23.1 8.7 0.00011 22.3 8.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 EAX94045.1 - 0.00011 21.6 2.0 0.00018 21.0 2.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_11 PF17123.5 EAX94045.1 - 0.0027 17.4 5.4 0.0068 16.1 5.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EAX94045.1 - 0.0045 17.0 2.7 0.0084 16.1 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 EAX94045.1 - 0.0081 16.3 2.6 0.012 15.8 2.6 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain U-box PF04564.15 EAX94045.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 EAX94045.1 - 0.015 15.1 7.9 0.03 14.1 7.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 EAX94045.1 - 0.016 15.4 2.5 0.025 14.8 2.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-Nse PF11789.8 EAX94045.1 - 0.054 13.3 5.7 0.11 12.3 5.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EAX94045.1 - 0.056 13.3 6.1 0.092 12.6 6.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 EAX94045.1 - 0.079 12.6 10.0 0.12 12.0 10.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type BLACT_WH PF17778.1 EAX94045.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain zf-RING_10 PF16685.5 EAX94045.1 - 0.15 12.2 8.0 0.26 11.4 8.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_RING PF05883.11 EAX94045.1 - 0.38 10.7 2.6 1.2 9.2 2.6 1.9 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF1272 PF06906.11 EAX94045.1 - 0.77 9.9 9.1 1.5 8.9 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.14 EAX94045.1 - 2.4 7.9 11.3 2.3 7.9 9.6 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_5 PF17121.5 EAX94045.1 - 2.9 7.9 8.8 6.2 6.8 7.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 EAX94046.1 - 2e-15 56.9 2.9 0.0001 23.0 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94046.1 - 2.6e-11 43.7 0.1 0.00063 20.0 0.8 3.7 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX94046.1 - 0.00071 19.5 0.2 0.22 11.4 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAX94046.1 - 0.002 17.2 0.0 0.017 14.1 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1314 PF07013.11 EAX94046.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) PQQ PF01011.21 EAX94046.1 - 0.15 12.0 0.2 2 8.5 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat NBD_C PF17042.5 EAX94046.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Frtz PF11768.8 EAX94046.1 - 0.2 9.9 0.0 0.33 9.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cofilin_ADF PF00241.20 EAX94047.1 - 3.9e-18 65.4 0.0 4.4e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 EAX94047.1 - 0.14 12.8 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Collagenase LRR_5 PF13306.6 EAX94048.1 - 0 1096.7 181.1 9.1e-27 93.6 2.9 15.5 2 2 16 18 18 18 18 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94048.1 - 3.7e-49 164.3 3.7 0.0083 15.9 0.0 27.6 20 7 12 32 32 32 19 Leucine rich repeat LRR_5 PF13306.6 EAX94049.1 - 5.6e-58 194.5 18.2 1.2e-21 76.9 5.5 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94049.1 - 3.6e-13 49.0 0.0 0.0094 15.7 0.1 7.1 3 2 5 8 8 8 5 Leucine rich repeat Cys_Met_Meta_PP PF01053.20 EAX94049.1 - 0.0052 15.4 0.1 0.61 8.5 0.0 2.4 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Herpes_gI PF01688.17 EAX94049.1 - 0.01 15.7 0.7 4.5 7.2 0.0 3.3 3 1 0 3 3 3 0 Alphaherpesvirus glycoprotein I LRR_5 PF13306.6 EAX94050.1 - 4.5e-22 78.4 3.8 4.5e-22 78.4 3.8 1.9 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94050.1 - 0.00012 21.8 0.0 0.19 11.5 0.0 3.9 2 1 3 5 5 5 2 Leucine rich repeat DUF4170 PF13773.6 EAX94050.1 - 0.013 15.6 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Cadherin_pro PF08758.11 EAX94050.1 - 0.017 15.3 0.8 7.2 6.9 0.0 3.2 2 1 0 3 3 3 0 Cadherin prodomain like ZF-HD_dimer PF04770.12 EAX94050.1 - 3 8.3 0.0 3 8.3 0.0 2.8 2 1 0 2 2 2 0 ZF-HD protein dimerisation region Pkinase PF00069.25 EAX94051.1 - 3.6e-58 197.0 0.1 4.1e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94051.1 - 1.4e-25 90.0 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX94051.1 - 1e-07 31.3 1.2 3.2e-07 29.6 1.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAX94051.1 - 4.8e-05 23.0 0.3 7.1e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EAX94051.1 - 6.3e-05 22.6 0.4 0.0001 22.0 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EAX94051.1 - 0.00015 21.2 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX94051.1 - 0.00074 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX94051.1 - 0.017 14.4 0.0 0.29 10.4 0.0 2.5 3 1 0 3 3 3 0 Kinase-like CPSF100_C PF13299.6 EAX94052.1 - 4.2 7.5 7.8 4.5 7.4 7.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 EAX94052.1 - 4.3 7.2 13.2 4.5 7.2 13.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Peptidase_S49_N PF08496.10 EAX94052.1 - 9.5 6.3 7.7 8.8 6.4 7.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM176 PF14851.6 EAX94052.1 - 9.6 5.9 7.5 9.5 5.9 7.5 1.1 1 0 0 1 1 1 0 FAM176 family Ras PF00071.22 EAX94054.1 - 5e-39 133.5 0.1 5.8e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94054.1 - 5.3e-31 107.3 0.0 9.2e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94054.1 - 1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX94054.1 - 7.4e-09 35.3 0.1 1.6e-08 34.2 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX94054.1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX94054.1 - 2.2e-06 27.3 0.9 4.3e-06 26.4 0.2 1.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 EAX94054.1 - 4.9e-06 26.0 0.4 0.0054 16.1 0.0 2.1 1 1 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 EAX94054.1 - 6.9e-06 26.1 2.7 0.0072 16.2 0.3 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAX94054.1 - 0.00011 22.7 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EAX94054.1 - 0.00072 19.1 0.3 0.0037 16.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region TPM_phosphatase PF04536.14 EAX94054.1 - 0.00077 19.6 0.1 0.0015 18.7 0.1 1.5 1 0 0 1 1 1 1 TPM domain ATP_bind_1 PF03029.17 EAX94054.1 - 0.0016 18.3 0.4 0.24 11.2 0.2 2.8 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAX94054.1 - 0.003 17.0 0.0 0.0051 16.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX94054.1 - 0.0061 16.3 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EAX94054.1 - 0.007 16.4 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EAX94054.1 - 0.011 16.2 0.2 0.018 15.6 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EAX94054.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 EAX94054.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_24 PF13479.6 EAX94054.1 - 0.019 14.7 1.5 0.073 12.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX94054.1 - 0.024 15.1 0.1 0.055 13.9 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAX94054.1 - 0.036 13.8 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EAX94054.1 - 0.041 13.0 0.0 0.09 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EAX94054.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.12 EAX94054.1 - 0.051 12.5 0.1 1.5 7.7 0.1 2.2 1 1 1 2 2 2 0 YcjX-like family, DUF463 RE_AlwI PF09491.10 EAX94054.1 - 0.052 12.3 0.1 0.057 12.2 0.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease AAA_29 PF13555.6 EAX94054.1 - 0.054 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EAX94054.1 - 0.07 12.3 0.5 0.16 11.1 0.4 1.8 1 1 0 1 1 1 0 G-protein alpha subunit cobW PF02492.19 EAX94054.1 - 0.071 12.7 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EAX94054.1 - 0.086 12.5 1.6 5.9 6.5 0.1 2.9 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EAX94054.1 - 0.089 12.5 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EAX94054.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EAX94054.1 - 0.11 12.0 0.1 0.39 10.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EAX94054.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein CARD PF00619.21 EAX94054.1 - 0.13 12.3 0.1 0.37 10.9 0.0 1.6 1 1 1 2 2 2 0 Caspase recruitment domain TPR_12 PF13424.6 EAX94055.1 - 2.8e-23 82.0 8.2 8.6e-09 35.6 0.3 4.4 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EAX94055.1 - 1.2e-16 59.7 3.6 5.5e-05 22.8 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAX94055.1 - 1.3e-15 56.1 8.5 0.00031 20.6 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAX94055.1 - 1.7e-13 49.6 13.6 0.0019 18.3 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EAX94055.1 - 6.2e-08 32.8 0.1 5.4 8.1 0.0 5.8 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX94055.1 - 1.1e-06 28.2 3.5 7.6 6.8 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAX94055.1 - 2e-06 27.4 1.1 0.0001 21.8 0.1 2.5 1 1 1 3 3 3 2 MalT-like TPR region SNAP PF14938.6 EAX94055.1 - 2.8e-06 26.9 6.2 1.9e-05 24.2 1.0 2.8 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 EAX94055.1 - 2.7e-05 23.9 0.5 31 4.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 EAX94055.1 - 7e-05 22.6 5.8 0.11 12.1 0.9 4.0 1 1 2 3 3 3 2 26S proteasome subunit RPN7 DUF3856 PF12968.7 EAX94055.1 - 0.00028 21.0 2.9 0.23 11.5 0.1 3.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EAX94055.1 - 0.0008 19.9 0.2 9.3 6.8 0.0 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat LANC_like PF05147.13 EAX94055.1 - 0.01 14.4 0.5 0.019 13.6 0.5 1.4 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein ANAPC3 PF12895.7 EAX94055.1 - 0.043 14.0 5.5 1.9 8.8 1.1 3.6 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAX94055.1 - 0.045 14.4 7.3 17 6.3 0.0 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat SPO22 PF08631.10 EAX94055.1 - 0.098 12.1 3.7 0.52 9.8 0.1 2.6 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like YkyA PF10368.9 EAX94055.1 - 3.4 7.3 8.7 0.93 9.1 3.8 2.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ABC_tran PF00005.27 EAX94056.1 - 1.5e-23 83.8 0.0 2.9e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX94056.1 - 0.00097 19.0 0.7 0.03 14.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX94056.1 - 0.0011 18.5 0.7 0.22 11.0 0.0 2.7 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EAX94056.1 - 0.0086 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EAX94056.1 - 0.01 15.7 0.1 0.036 14.0 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EAX94056.1 - 0.028 14.9 0.3 0.028 14.9 0.3 2.5 3 0 0 3 3 3 0 AAA domain PCI PF01399.27 EAX94057.1 - 2.8e-05 24.6 3.3 7.4e-05 23.2 1.0 2.8 2 1 0 2 2 2 1 PCI domain TM2 PF05154.16 EAX94058.1 - 0.051 13.9 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 TM2 domain Hormone_3 PF00159.18 EAX94058.1 - 0.55 10.3 2.9 3.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Pancreatic hormone peptide CLASP_N PF12348.8 EAX94059.1 - 1.4e-08 34.6 2.1 1.1e-07 31.7 1.2 2.8 3 1 1 4 4 4 1 CLASP N terminal SAM_Exu PF18609.1 EAX94059.1 - 0.11 12.6 0.7 1.9 8.7 0.1 3.3 2 1 1 3 3 3 0 Exuperantia SAM-like domain Nsp1 PF11501.8 EAX94059.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Non structural protein Nsp1 HEAT PF02985.22 EAX94059.1 - 0.28 11.6 4.9 42 4.8 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EAX94059.1 - 0.43 11.2 3.5 4.4 8.0 0.1 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region UBA PF00627.31 EAX94060.1 - 3.6e-11 42.7 1.4 1.5e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 EAX94060.1 - 4.9e-08 32.6 0.7 1.1e-07 31.5 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EAX94060.1 - 0.0032 17.2 0.4 0.006 16.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ral PF11058.8 EAX94060.1 - 0.033 13.8 0.1 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Antirestriction protein Ral Ubiquitin_4 PF18036.1 EAX94060.1 - 0.05 13.7 0.2 0.15 12.1 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 EAX94060.1 - 0.095 13.2 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Rad60-SLD_2 PF13881.6 EAX94060.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like B3R PF17057.5 EAX94060.1 - 0.23 11.7 1.1 0.4 10.9 0.3 1.8 2 1 0 2 2 2 0 Poxviridae B3 protein M16C_assoc PF08367.11 EAX94061.1 - 4.5e-52 176.7 0.3 8.7e-52 175.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAX94061.1 - 9.8e-21 74.6 1.1 7.1e-12 45.7 0.0 3.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAX94061.1 - 5e-12 46.0 0.4 1.2e-10 41.5 0.1 3.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DHHA1 PF02272.19 EAX94061.1 - 0.063 13.7 0.1 0.45 10.9 0.0 2.5 2 0 0 2 2 2 0 DHHA1 domain ATP-synt_B PF00430.18 EAX94061.1 - 0.095 12.8 0.3 0.18 11.9 0.3 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TFIID_20kDa PF03847.13 EAX94061.1 - 3.8 8.1 8.5 14 6.3 0.1 4.4 5 0 0 5 5 5 0 Transcription initiation factor TFIID subunit A DUF4795 PF16043.5 EAX94061.1 - 4.8 6.7 7.6 0.71 9.4 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Gly-zipper_Omp PF13488.6 EAX94062.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX94062.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94062.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pkinase PF00069.25 EAX94066.1 - 2.3e-70 237.0 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94066.1 - 3.9e-36 124.7 0.0 5.6e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX94066.1 - 1.4e-16 60.9 0.0 3.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 EAX94066.1 - 1.4e-08 35.3 0.2 2.9e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EAX94066.1 - 3.4e-07 29.9 0.0 6.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX94066.1 - 1.4e-05 24.6 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX94066.1 - 0.0002 21.4 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PH_11 PF15413.6 EAX94066.1 - 0.0034 17.8 0.3 0.051 14.0 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain FTA2 PF13095.6 EAX94066.1 - 0.01 15.5 0.1 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAX94066.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EAX94066.1 - 0.043 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EAX94066.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EAX94066.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HALZ PF02183.18 EAX94067.1 - 0.0073 16.5 8.4 0.0073 16.5 8.4 9.9 11 0 0 11 11 11 2 Homeobox associated leucine zipper OST_P2 PF18235.1 EAX94067.1 - 5.3 7.0 9.7 0.59 10.1 0.3 3.6 3 0 0 3 3 3 0 Oligosaccharyltransferase Peripheral 2 domain XRN_M PF17846.1 EAX94068.1 - 0.75 8.7 8.7 1.3 7.9 8.7 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Atg14 PF10186.9 EAX94068.1 - 4.2 6.4 18.3 9.3 5.2 17.6 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0184 PF03670.13 EAX94068.1 - 4.7 7.7 12.4 0.15 12.5 0.9 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Histone PF00125.24 EAX94069.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX94069.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX94069.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX94069.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Histone PF00125.24 EAX94070.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX94070.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX94070.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone E2F_TDP PF02319.20 EAX94071.1 - 3.8e-06 26.9 0.0 0.049 13.7 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain GPS2_interact PF15784.5 EAX94073.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX94073.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX94075.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX94076.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94076.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX94077.1 - 0.034 14.0 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX94078.1 - 5.2e-72 241.3 4.1 7.9e-72 240.7 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX94078.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Ank_2 PF12796.7 EAX94081.1 - 2.6e-24 85.6 14.0 1.4e-16 60.8 3.6 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94081.1 - 3.5e-19 68.9 3.6 1.8e-08 34.8 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94081.1 - 5.9e-15 53.9 3.5 1.9e-06 27.7 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX94081.1 - 1.5e-11 44.3 1.0 1.8e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94081.1 - 1.6e-10 40.9 3.5 0.00052 20.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Phage_capsid PF05065.13 EAX94081.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family Peptidase_M8 PF01457.16 EAX94082.1 - 8.4e-37 127.0 0.1 1.5e-36 126.2 0.1 1.3 1 0 0 1 1 1 1 Leishmanolysin LCAT PF02450.15 EAX94083.1 - 1.2e-24 87.2 0.0 9.7e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EAX94083.1 - 0.2 12.2 0.0 0.31 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PSP PF04046.16 EAX94085.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94086.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX94088.1 - 2.9e-05 24.0 3.4 5.7e-05 23.1 0.2 3.1 2 1 0 2 2 2 1 Phage tail repeat like DUF445 PF04286.12 EAX94088.1 - 0.0056 16.5 3.5 0.0078 16.1 3.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF1048 PF06304.11 EAX94088.1 - 0.027 14.9 0.6 0.076 13.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF3417 PF11897.8 EAX94088.1 - 0.041 14.3 1.3 0.21 12.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4116 PF13475.6 EAX94088.1 - 0.066 13.0 0.1 0.23 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4477 PF14780.6 EAX94090.1 - 7.2 6.2 7.4 5.5 6.6 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Zn_dep_PLPC PF00882.18 EAX94091.1 - 9.8e-06 25.7 0.1 1.2e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Zinc dependent phospholipase C Phycobilisome PF00502.19 EAX94092.1 - 0.0049 16.8 32.6 10 6.1 0.0 11.6 10 3 5 15 15 15 6 Phycobilisome protein APG6_N PF17675.1 EAX94092.1 - 0.063 13.8 577.3 0.4 11.2 28.7 23.7 1 1 23 25 25 25 0 Apg6 coiled-coil region DUF2897 PF11446.8 EAX94093.1 - 1 9.3 3.5 2.2 8.3 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Cas_Csa5 PF09702.10 EAX94094.1 - 0.00025 21.3 1.9 51 4.2 0.0 4.7 1 1 4 5 5 5 0 CRISPR-associated protein (Cas_Csa5) TraC PF07820.12 EAX94094.1 - 0.089 13.1 2.6 56 4.2 0.1 3.4 1 1 3 4 4 4 0 TraC-like protein FliG_C PF01706.16 EAX94094.1 - 0.1 12.8 9.4 53 4.1 0.1 4.7 1 1 4 5 5 5 0 FliG C-terminal domain Retinin_C PF04527.12 EAX94094.1 - 0.17 12.1 12.0 46 4.4 0.1 4.6 5 0 0 5 5 5 0 Drosophila Retinin like protein UK PF02512.14 EAX94094.1 - 0.23 12.0 6.8 91 3.7 0.1 4.1 1 1 3 4 4 4 0 Virulence determinant Wzt_C PF14524.6 EAX94094.1 - 0.25 11.4 4.5 24 4.9 0.1 3.3 1 1 3 4 4 4 0 Wzt C-terminal domain Cnd1 PF12717.7 EAX94094.1 - 1.1 9.2 10.1 8 6.5 1.0 2.6 1 1 3 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CSTF2_hinge PF14327.6 EAX94094.1 - 3.7 8.1 23.7 40 4.8 0.4 5.2 5 0 0 5 5 5 0 Hinge domain of cleavage stimulation factor subunit 2 EloA-BP1 PF15870.5 EAX94094.1 - 3.7 7.8 24.7 11 6.2 4.6 3.5 1 1 3 4 4 4 0 ElonginA binding-protein 1 PRIMA1 PF16101.5 EAX94096.1 - 0.0087 16.1 0.8 0.012 15.7 0.8 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 FtsL PF04999.13 EAX94096.1 - 0.098 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsL TPR_MLP1_2 PF07926.12 EAX94099.1 - 0.0078 16.3 5.8 0.0078 16.3 5.8 9.7 5 2 4 9 9 9 7 TPR/MLP1/MLP2-like protein Shisa PF13908.6 EAX94100.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Lipocalin_5 PF13924.6 EAX94100.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Lipocalin-like domain Pkinase PF00069.25 EAX94101.1 - 9.8e-31 107.1 2.6 1.6e-28 99.8 2.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94101.1 - 7.4e-15 54.9 0.7 4e-12 46.0 0.7 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94101.1 - 0.00011 21.6 0.0 0.016 14.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Ank_2 PF12796.7 EAX94102.1 - 5.1e-106 347.4 20.4 1.5e-18 67.2 0.1 8.1 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94102.1 - 2.6e-76 249.0 0.1 1.7e-05 25.1 0.0 14.7 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.6 EAX94102.1 - 1.5e-68 226.3 2.0 6.9e-11 42.5 0.0 10.6 7 4 3 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94102.1 - 8.6e-63 200.9 2.1 0.00061 20.0 0.0 14.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 EAX94102.1 - 1.6e-61 203.6 7.6 9.4e-08 32.2 0.0 13.7 4 2 11 15 15 15 14 Ankyrin repeats (many copies) T3SS_ATPase_C PF18269.1 EAX94102.1 - 0.29 11.0 1.2 2.4 8.1 0.1 3.2 4 0 0 4 4 4 0 T3SS EscN ATPase C-terminal domain SusF_SusE PF16411.5 EAX94103.1 - 0.095 13.2 4.4 0.11 13.0 2.2 2.2 2 0 0 2 2 2 0 Outer membrane protein SusF_SusE DUF4625 PF15418.6 EAX94104.1 - 0.0094 16.2 6.3 0.97 9.7 0.7 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4625) DUF4469 PF14734.6 EAX94104.1 - 0.028 14.6 2.2 2.2 8.5 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4469) with IG-like fold DUF5385 PF17359.2 EAX94105.1 - 6.8e-05 22.5 0.1 8.4e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5385) SKG6 PF08693.10 EAX94105.1 - 0.00017 20.9 7.1 0.00026 20.3 7.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EAX94105.1 - 0.00033 21.5 0.0 0.00051 20.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAX94105.1 - 0.0025 17.7 0.1 0.0033 17.3 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain Insulin_TMD PF17870.1 EAX94105.1 - 0.0031 17.6 1.2 0.0041 17.1 1.2 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Herpes_gE PF02480.16 EAX94105.1 - 0.0031 16.3 0.0 0.0034 16.2 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 EAX94105.1 - 0.0081 16.6 0.1 0.0093 16.4 0.1 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Baculo_11_kDa PF06143.11 EAX94105.1 - 0.013 15.1 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5305 PF17231.2 EAX94105.1 - 0.019 14.4 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DAP10 PF07213.11 EAX94105.1 - 0.023 14.7 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 DAP10 membrane protein Protocadherin PF08374.11 EAX94105.1 - 0.024 14.6 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Orf78 PF06024.12 EAX94105.1 - 0.027 14.8 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4577 PF15145.6 EAX94105.1 - 0.031 14.3 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) RIFIN PF02009.16 EAX94105.1 - 0.034 14.0 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 EAX94105.1 - 0.039 14.1 4.7 0.03 14.4 3.9 1.3 1 1 0 1 1 1 0 Podoplanin Chordopox_A13L PF05961.11 EAX94105.1 - 0.051 13.8 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEM154 PF15102.6 EAX94105.1 - 0.053 13.4 2.3 0.066 13.1 2.3 1.3 1 1 0 1 1 1 0 TMEM154 protein family YajC PF02699.15 EAX94105.1 - 0.092 12.6 1.5 0.097 12.6 0.6 1.5 1 1 1 2 2 2 0 Preprotein translocase subunit FeoB_associated PF12669.7 EAX94105.1 - 0.098 13.1 2.5 0.15 12.5 2.5 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ly49 PF08391.10 EAX94105.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region 7TM_GPCR_Srv PF10323.9 EAX94105.1 - 0.16 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 EAX94105.1 - 0.2 11.9 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.11 EAX94105.1 - 0.32 10.7 1.5 0.41 10.4 1.4 1.2 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF4832 PF16116.5 EAX94107.1 - 0.0076 16.1 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4832) Arrestin_C PF02752.22 EAX94107.1 - 0.031 14.7 0.1 0.091 13.2 0.1 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF4625 PF15418.6 EAX94107.1 - 0.051 13.8 0.6 0.15 12.3 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4625) DUF4106 PF13388.6 EAX94108.1 - 1.6e-256 851.2 16.6 1.8e-256 851.0 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX94108.1 - 0.01 16.1 0.1 0.54 10.6 0.2 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated Pox_A32 PF04665.12 EAX94109.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX94109.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX94109.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX94109.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX94109.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX94109.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX94109.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX94109.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX94109.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX94109.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX94109.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX94109.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX94111.1 - 6.1e-63 211.0 5.9 6.7e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly_rich PF12810.7 EAX94114.1 - 5.8e-21 75.5 26.5 9.7e-21 74.8 26.5 1.2 1 0 0 1 1 1 1 Glycine rich protein Thioredoxin PF00085.20 EAX94115.1 - 9.5e-12 44.8 0.2 2.5e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX94115.1 - 0.02 15.3 0.4 0.13 12.8 0.4 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX94115.1 - 0.055 13.8 7.9 9.3 6.7 1.1 4.3 2 2 2 4 4 4 0 Thioredoxin-like Peptidase_S8 PF00082.22 EAX94116.1 - 4.5e-13 49.1 0.1 6.5e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DUF4448 PF14610.6 EAX94117.1 - 0.0019 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3671 PF12420.8 EAX94117.1 - 0.0094 16.0 5.2 0.026 14.6 5.2 1.8 1 1 0 1 1 1 1 Protein of unknown function Orf78 PF06024.12 EAX94117.1 - 0.032 14.5 0.2 0.032 14.5 0.2 2.3 1 1 1 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 EAX94117.1 - 0.037 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1646 PF07854.12 EAX94117.1 - 0.067 12.6 1.7 0.095 12.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1646) DUF5453 PF17534.2 EAX94117.1 - 0.074 13.0 0.6 0.074 13.0 0.6 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5453) Shisa PF13908.6 EAX94117.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SRTM1 PF15872.5 EAX94117.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 1 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 TALPID3 PF15324.6 EAX94117.1 - 0.58 7.8 8.2 0.29 8.8 6.5 1.3 1 1 0 1 1 1 0 Hedgehog signalling target Cortexin PF11057.8 EAX94117.1 - 0.63 9.9 3.3 0.35 10.8 0.6 1.9 1 1 1 2 2 2 0 Cortexin of kidney Pox_A32 PF04665.12 EAX94120.1 - 5.1e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX94120.1 - 0.0051 16.8 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX94120.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Gly-zipper_Omp PF13488.6 EAX94122.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX94122.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94122.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAX94123.1 - 1.3e-77 258.6 11.7 1.4e-77 258.5 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Lactamase_B PF00753.27 EAX94125.1 - 8.4e-24 84.7 0.1 1.2e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAX94125.1 - 6.3e-05 22.6 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAX94125.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EAX94125.1 - 0.13 11.7 0.1 0.49 9.8 0.0 1.8 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily domain HAGH_C PF16123.5 EAX94125.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Helicase_C PF00271.31 EAX94126.1 - 7.5e-22 77.8 0.3 1.5e-16 60.7 0.0 3.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EAX94126.1 - 1.7e-19 70.3 0.0 3.9e-18 65.8 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EAX94126.1 - 1.6e-14 54.4 8.2 4.3e-14 53.0 5.4 3.0 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 EAX94126.1 - 1.4e-08 34.6 0.1 2.8e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 HRDC domain PTR PF12789.7 EAX94127.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 3.9 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX94127.1 - 0.01 15.7 3.8 0.017 14.9 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX94127.1 - 0.058 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX94127.1 - 0.12 12.8 3.4 0.19 12.2 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) MeaB PF03308.16 EAX94127.1 - 0.13 11.3 1.0 0.22 10.5 1.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PTR PF12789.7 EAX94128.1 - 2.7e-10 40.1 7.2 5.6e-09 35.9 1.8 6.1 5 2 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX94128.1 - 0.041 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX94129.1 - 0.029 14.8 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX94129.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Trypan_PARP PF05887.11 EAX94130.1 - 0.0069 16.4 0.1 0.0069 16.4 0.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX94130.1 - 0.058 14.0 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX94131.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3877 PF12993.7 EAX94132.1 - 0.039 13.8 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) LRR_4 PF12799.7 EAX94133.1 - 0.0038 17.6 1.4 0.06 13.8 0.2 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX94133.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeat Ras PF00071.22 EAX94134.1 - 3.6e-53 179.5 0.0 4.3e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94134.1 - 4.5e-32 110.8 0.2 6.6e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94134.1 - 1.5e-10 40.8 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX94134.1 - 4.9e-07 29.8 0.1 3.6e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX94134.1 - 4.8e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX94134.1 - 0.0003 20.2 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX94134.1 - 0.00086 19.4 0.0 0.0017 18.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAX94134.1 - 0.002 17.7 0.0 0.0088 15.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 EAX94134.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2225 PF09986.9 EAX94134.1 - 0.097 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3450 PF11932.8 EAX94135.1 - 0.0028 17.0 14.4 0.0028 17.0 14.4 7.5 3 1 4 8 8 8 1 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 EAX94135.1 - 0.0037 16.9 15.8 0.0037 16.9 15.8 6.3 3 2 3 7 7 7 1 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 EAX94135.1 - 0.015 15.8 11.5 0.015 15.8 11.5 7.8 4 1 2 6 6 6 0 Apg6 coiled-coil region TBD PF12845.7 EAX94135.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.3 4 0 0 4 4 4 0 TBD domain TSC22 PF01166.18 EAX94135.1 - 0.92 9.9 39.2 1.5 9.2 1.8 7.9 5 2 2 7 7 7 0 TSC-22/dip/bun family Eno-Rase_FAD_bd PF07055.12 EAX94135.1 - 1.5 9.3 4.2 8.5 6.9 1.2 4.1 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Ank_2 PF12796.7 EAX94136.1 - 7.8e-115 375.7 85.0 1e-19 70.9 6.3 11.7 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94136.1 - 8.8e-113 364.3 47.5 1.1e-07 32.0 0.0 17.5 18 0 0 18 18 18 16 Ankyrin repeat Ank_4 PF13637.6 EAX94136.1 - 2.3e-110 359.7 45.7 1.7e-13 50.8 0.2 18.1 4 1 14 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94136.1 - 2.2e-94 297.9 51.7 2.6e-06 27.3 0.0 18.7 19 0 0 19 19 19 17 Ankyrin repeat Ank_5 PF13857.6 EAX94136.1 - 1.7e-88 289.5 71.7 2.7e-13 49.9 0.7 13.0 3 2 11 15 15 15 15 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94136.1 - 2.3e-20 72.3 9.9 2.3e-20 72.3 9.9 7.5 3 1 4 9 9 9 2 Domain of unknown function (DUF3447) BRCT_2 PF16589.5 EAX94136.1 - 0.0045 17.4 11.2 1.8 9.1 1.9 6.6 3 1 3 6 6 6 1 BRCT domain, a BRCA1 C-terminus domain DUF5535 PF17687.1 EAX94136.1 - 0.049 13.8 0.0 57 3.9 0.0 4.4 3 1 2 6 6 6 0 Family of unknown function (DUF5535) RL11D PF11088.8 EAX94137.1 - 0.14 12.5 0.1 0.22 11.8 0.1 1.3 1 1 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Pkinase PF00069.25 EAX94138.1 - 2.1e-63 214.2 0.0 2.4e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94138.1 - 2e-30 106.0 0.0 4.1e-28 98.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EAX94138.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX94138.1 - 0.0009 18.3 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX94138.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX94138.1 - 0.0036 16.9 0.1 0.0051 16.4 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAX94138.1 - 0.0056 16.3 0.1 0.0079 15.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EAX94138.1 - 0.0057 16.0 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX94138.1 - 0.13 11.0 0.0 0.27 10.0 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase DUF4572 PF15139.6 EAX94140.1 - 0.052 13.5 6.7 0.092 12.7 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4572) Syntaxin-6_N PF09177.11 EAX94140.1 - 0.43 11.2 4.8 0.64 10.6 2.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 EAX94140.1 - 0.47 10.7 3.8 3.3 8.0 0.1 2.9 3 0 0 3 3 3 0 Haemolysin XhlA YabA PF06156.13 EAX94140.1 - 7 7.3 9.8 1.2 9.8 5.1 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 EAX94141.1 - 1.7e-69 234.1 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94141.1 - 2.5e-43 148.2 0.0 3.8e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX94141.1 - 3.7e-08 32.7 0.8 3.7e-08 32.7 0.8 1.8 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EAX94141.1 - 6.8e-05 22.5 0.6 6.8e-05 22.5 0.6 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EAX94141.1 - 8.5e-05 22.0 0.0 0.00027 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX94141.1 - 0.0033 16.8 0.1 0.0061 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_Nse1 PF07574.13 EAX94141.1 - 0.0082 16.1 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex Choline_kinase PF01633.20 EAX94141.1 - 0.0098 15.5 1.4 0.013 15.1 0.2 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Thiolase_C PF02803.18 EAX94141.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Thiolase, C-terminal domain APH PF01636.23 EAX94141.1 - 0.081 12.8 0.2 0.57 10.1 0.3 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Spo12 PF05032.12 EAX94142.1 - 1.1 9.2 10.6 0.21 11.5 2.9 3.1 4 0 0 4 4 4 0 Spo12 family FYVE_2 PF02318.16 EAX94143.1 - 0.044 14.0 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 EAX94146.1 - 1.6e-12 47.9 0.1 6.2e-06 26.7 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94146.1 - 1.8e-12 47.3 0.3 0.00047 20.4 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX94146.1 - 4e-12 46.4 1.3 0.0038 17.8 0.0 3.9 3 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94146.1 - 2.9e-06 27.2 4.3 1.1 10.1 0.0 5.3 5 3 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAX94146.1 - 3.2e-05 24.2 1.1 7.4 7.2 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Bromodomain PF00439.25 EAX94147.1 - 6.6e-21 74.2 0.4 4.8e-20 71.4 0.1 2.3 2 0 0 2 2 2 1 Bromodomain VPR PF00522.18 EAX94147.1 - 0.17 12.0 1.1 0.37 10.8 0.6 1.8 2 0 0 2 2 2 0 VPR/VPX protein RPAP3_C PF13877.6 EAX94147.1 - 0.17 12.4 1.0 1.1 9.8 0.4 2.4 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 RNA_pol_Rpb2_4 PF04566.13 EAX94148.1 - 1.7 9.0 3.7 4.1 7.8 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 ELP6 PF09807.9 EAX94149.1 - 0.049 13.0 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongation complex protein 6 Ank_2 PF12796.7 EAX94150.1 - 6.1e-31 106.9 9.4 1.1e-15 58.0 0.3 3.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX94150.1 - 3.8e-29 100.5 7.0 9.4e-27 92.8 2.7 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX94150.1 - 3.6e-21 74.9 1.3 1.7e-08 34.5 0.1 2.9 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX94150.1 - 4.9e-21 74.2 0.3 9.6e-08 32.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX94150.1 - 1.3e-19 70.3 1.1 2.8e-09 37.3 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94150.1 - 9.3e-17 59.4 2.2 5.2e-05 23.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat zf-TFIIB PF13453.6 EAX94152.1 - 2.3 7.6 4.5 1.3 8.4 0.1 2.6 3 0 0 3 3 3 0 Transcription factor zinc-finger G-patch PF01585.23 EAX94153.1 - 0.0075 16.1 0.5 0.0075 16.1 0.5 1.8 2 0 0 2 2 2 1 G-patch domain Thioesterase PF00975.20 EAX94153.1 - 0.08 13.0 0.1 0.089 12.9 0.1 1.0 1 0 0 1 1 1 0 Thioesterase domain G-patch_2 PF12656.7 EAX94153.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.5 2 1 0 2 2 2 0 G-patch domain HSP70 PF00012.20 EAX94153.1 - 0.2 9.8 3.7 0.23 9.6 3.7 1.0 1 0 0 1 1 1 0 Hsp70 protein G0-G1_switch_2 PF15103.6 EAX94153.1 - 0.35 11.3 5.7 0.53 10.7 5.7 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 MAS20 PF02064.15 EAX94153.1 - 1.3 9.2 7.4 1.7 8.8 7.4 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor Importin_rep_6 PF18829.1 EAX94154.1 - 0.0053 16.9 1.5 0.0078 16.3 1.5 1.2 1 0 0 1 1 1 1 Importin repeat 6 Med6 PF04934.14 EAX94155.1 - 8.5e-13 48.3 0.1 1.3e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 MED6 mediator sub complex component WD40 PF00400.32 EAX94156.1 - 7.8e-59 194.3 17.4 1.1e-08 35.6 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94156.1 - 2e-16 60.0 0.4 0.0041 17.4 0.0 6.1 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX94156.1 - 5.2e-13 49.0 0.1 0.093 12.0 0.0 4.5 4 1 0 4 4 4 4 WD40-like domain eIF2A PF08662.11 EAX94156.1 - 8.6e-10 38.8 2.2 3.3e-05 23.8 0.4 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAX94156.1 - 5.7e-05 22.2 1.3 8.7 5.2 0.0 5.1 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAX94156.1 - 0.00017 20.4 8.0 0.69 8.5 0.2 4.8 1 1 5 6 6 6 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EAX94156.1 - 0.0071 16.4 0.3 8.4 6.5 0.0 4.4 3 3 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region NinE PF05322.11 EAX94156.1 - 0.013 15.4 0.5 16 5.5 0.0 4.1 5 0 0 5 5 5 0 NINE Protein Nucleoporin_N PF08801.11 EAX94156.1 - 0.038 12.7 0.1 0.11 11.3 0.1 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Ank_2 PF12796.7 EAX94157.1 - 7.5e-50 167.5 20.2 7e-20 71.4 0.6 6.3 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94157.1 - 1.7e-42 143.2 15.6 1.1e-09 38.7 0.0 9.0 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX94157.1 - 6.5e-42 140.2 11.2 2.3e-06 27.8 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX94157.1 - 2.8e-36 119.4 12.4 0.00043 20.5 0.0 10.2 10 1 1 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EAX94157.1 - 2.8e-34 116.7 14.5 3e-08 33.7 0.0 7.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94157.1 - 9.6e-19 67.1 4.1 9.6e-19 67.1 4.1 5.5 3 3 5 8 8 8 1 Domain of unknown function (DUF3447) Pico_P2A PF00947.19 EAX94157.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A Mic1 PF07035.12 EAX94157.1 - 0.079 12.7 0.2 22 4.7 0.0 3.3 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like End_tail_spike PF12219.8 EAX94157.1 - 0.082 13.0 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Catalytic domain of bacteriophage endosialidase POR_N PF01855.19 EAX94158.1 - 9.8e-58 195.6 0.1 1.6e-57 194.9 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EAX94158.1 - 1.4e-23 83.9 0.0 2.9e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EAX94158.1 - 9.5e-13 48.3 0.0 3.1e-12 46.7 0.0 2.0 2 0 0 2 2 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_C PF02775.21 EAX94158.1 - 1.3e-11 44.5 0.0 4.7e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 EAX94158.1 - 5.8e-07 30.0 8.0 1.8e-06 28.4 8.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EAX94158.1 - 8.1e-07 28.6 9.8 0.0038 17.0 2.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EAX94158.1 - 1.4e-06 29.1 6.4 0.0028 18.5 0.9 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EAX94158.1 - 5.1e-06 26.5 5.9 1e-05 25.6 4.8 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAX94158.1 - 6.9e-06 26.1 7.5 6.9e-06 26.1 7.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAX94158.1 - 1.9e-05 25.0 7.6 6e-05 23.4 7.2 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EAX94158.1 - 2.2e-05 24.5 11.0 0.00015 21.8 11.0 2.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAX94158.1 - 0.00029 20.8 13.6 0.001 19.0 4.1 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain EKR PF10371.9 EAX94158.1 - 0.0022 17.7 0.0 0.0065 16.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function Transketolase_C PF02780.20 EAX94158.1 - 0.0074 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain RapA_C PF12137.8 EAX94158.1 - 0.024 13.6 0.3 0.079 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Fer4_17 PF13534.6 EAX94158.1 - 0.059 13.9 13.0 0.27 11.8 11.8 2.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EAX94158.1 - 0.48 10.6 19.3 0.026 14.6 3.2 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 EAX94158.1 - 6.3 7.6 16.2 13 6.6 5.1 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain PDCD9 PF07147.12 EAX94159.1 - 0.027 13.7 0.1 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) HEAT PF02985.22 EAX94159.1 - 0.16 12.3 0.2 10 6.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Ank_2 PF12796.7 EAX94160.1 - 1.1e-16 61.2 0.1 9.8e-09 35.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94160.1 - 5.7e-14 51.8 0.8 0.00019 21.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX94160.1 - 1.5e-13 49.6 3.4 0.018 15.5 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX94160.1 - 1.3e-11 44.5 1.7 0.0037 17.5 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX94160.1 - 4e-10 40.0 0.1 7.1e-05 23.3 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94160.1 - 0.12 12.4 2.3 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) PPTA PF01239.22 EAX94161.1 - 8.4e-07 28.5 2.4 0.19 11.5 0.0 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DER1 PF04511.15 EAX94164.1 - 9e-22 77.9 13.3 1.1e-21 77.6 13.3 1.1 1 0 0 1 1 1 1 Der1-like family DUF2070 PF09843.9 EAX94164.1 - 4.3 5.5 19.3 5.3 5.2 19.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ARL2_Bind_BART PF11527.8 EAX94165.1 - 3.4e-24 85.2 2.6 3.4e-24 85.2 2.6 1.9 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Nucleo_P87 PF07267.11 EAX94165.1 - 0.04 12.8 7.5 0.052 12.4 7.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1682 PF07946.14 EAX94165.1 - 0.079 12.2 9.9 0.12 11.5 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) OmpH PF03938.14 EAX94165.1 - 0.55 10.6 8.2 1.3 9.4 8.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4837 PF16125.5 EAX94165.1 - 4.7 6.2 6.9 5.5 5.9 5.5 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4837) GGDEF PF00990.21 EAX94167.1 - 0.033 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX94167.1 - 1.4 8.9 5.3 2.8 7.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX94168.1 - 5.3e-64 214.5 7.5 5.9e-64 214.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX94168.1 - 0.1 12.9 0.1 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Ras PF00071.22 EAX94169.1 - 5.1e-38 130.2 0.0 5.8e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94169.1 - 5.4e-24 84.7 0.0 9.5e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94169.1 - 1.8e-14 53.6 0.0 2.1e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX94169.1 - 3e-05 23.5 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EAX94169.1 - 9.7e-05 22.3 0.2 0.00022 21.1 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EAX94169.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX94169.1 - 0.0035 16.7 0.1 0.0041 16.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region HECT PF00632.25 EAX94171.1 - 5.2e-56 190.4 0.0 1.3e-55 189.1 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CUB PF00431.20 EAX94171.1 - 0.00011 22.5 0.1 0.0005 20.4 0.1 2.2 1 0 0 1 1 1 1 CUB domain SPRY PF00622.28 EAX94171.1 - 0.0021 18.2 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 SPRY domain BBL5 PF07289.11 EAX94172.1 - 5.2e-93 311.7 1.2 6.5e-93 311.4 1.2 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 EAX94172.1 - 0.00094 19.3 0.1 0.21 11.8 0.0 3.2 2 1 1 3 3 3 1 Vacuolar protein sorting protein 36 Vps36 PMT PF02366.18 EAX94173.1 - 6.8e-07 29.1 8.3 6.8e-07 29.1 8.3 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Dynamin_N PF00350.23 EAX94174.1 - 3.2e-07 30.5 0.8 8.8e-06 25.9 0.8 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EAX94174.1 - 3e-06 27.3 0.0 7.6e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Bax1-I PF01027.20 EAX94174.1 - 0.017 14.9 0.4 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 RHD3 PF05879.12 EAX94174.1 - 0.072 11.2 0.8 1.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) DUF3447 PF11929.8 EAX94175.1 - 8.2e-38 128.2 7.1 8.2e-38 128.2 7.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94175.1 - 1.7e-08 34.9 4.8 0.00064 20.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94175.1 - 3.1e-05 24.0 1.2 11 7.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EAX94175.1 - 0.00047 20.7 0.9 6.5 7.5 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94175.1 - 0.012 16.0 0.1 5.3 7.5 0.0 3.9 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Guanylate_cyc PF00211.20 EAX94177.1 - 4.3e-43 147.0 0.0 8.6e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX94177.1 - 2.4e-10 40.6 0.2 1.3e-09 38.3 0.1 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX94177.1 - 1e-08 35.1 0.7 3.3e-08 33.5 0.1 2.2 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 EAX94177.1 - 5.3e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold DcuA_DcuB PF03605.14 EAX94177.1 - 0.024 13.6 6.0 1.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Anaerobic c4-dicarboxylate membrane transporter PAS_8 PF13188.7 EAX94177.1 - 0.031 14.3 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 EAX94177.1 - 0.088 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold TMEM132D_C PF15706.5 EAX94177.1 - 7.3 6.5 10.3 3.4 7.5 1.8 3.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term IFRD PF05004.13 EAX94178.1 - 6.4e-08 32.1 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF4108 PF13390.6 EAX94178.1 - 0.026 14.4 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) Spt20 PF12090.8 EAX94179.1 - 3.3e-23 82.5 4.2 4.4e-18 65.8 3.5 2.1 1 1 1 2 2 2 2 Spt20 family Pkinase PF00069.25 EAX94180.1 - 8.6e-27 94.1 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94180.1 - 9.4e-12 44.8 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX94180.1 - 0.00012 22.1 0.0 0.009 16.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX94180.1 - 0.00012 21.0 0.0 0.00027 19.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAX94180.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRCT_assoc PF12820.7 EAX94181.1 - 0.068 13.0 1.5 0.089 12.6 1.5 1.3 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT SHIPPO-rpt PF07004.12 EAX94182.1 - 5.3e-08 33.4 11.1 0.039 14.9 0.1 4.0 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat KIX_2 PF16987.5 EAX94182.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 KIX domain PSP PF04046.16 EAX94183.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94184.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX94185.1 - 0.077 13.5 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ank_4 PF13637.6 EAX94186.1 - 1.6e-33 114.6 2.6 3.5e-10 40.2 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94186.1 - 7.7e-31 106.5 0.5 2.8e-12 47.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94186.1 - 7e-27 93.1 0.5 2.6e-07 30.8 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94186.1 - 2.5e-26 88.8 0.8 4.6e-05 23.5 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EAX94186.1 - 8.2e-23 79.8 1.8 0.0002 21.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat DUF3447 PF11929.8 EAX94186.1 - 0.059 13.3 0.2 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94187.1 - 2.5e-71 236.3 13.5 2.3e-14 53.7 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94187.1 - 5.4e-48 160.8 10.2 2e-12 47.4 0.3 8.7 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94187.1 - 1.8e-40 136.4 4.3 1.8e-06 28.1 0.1 8.6 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94187.1 - 7.6e-38 124.2 4.9 0.00025 21.2 0.0 11.1 10 1 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 EAX94187.1 - 5.4e-32 108.8 6.5 0.00022 21.5 0.1 10.8 11 0 0 11 11 11 5 Ankyrin repeat DUF3447 PF11929.8 EAX94187.1 - 2.2e-09 37.1 3.6 9.4e-06 25.5 0.1 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Cytochrom_B_N_2 PF13631.6 EAX94187.1 - 0.0068 16.4 0.2 0.018 15.1 0.2 1.7 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB CclA_1 PF16942.5 EAX94187.1 - 0.092 13.0 0.4 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative cyclic bacteriocin SNase PF00565.17 EAX94188.1 - 4.1e-22 78.7 0.0 1.2e-06 29.0 0.0 5.4 5 0 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 EAX94188.1 - 3.3e-08 33.6 0.3 1.4e-06 28.3 0.0 3.6 4 1 0 4 4 4 1 Tudor domain PEPCK_GTP PF00821.18 EAX94189.1 - 6.4e-159 528.5 0.1 2.4e-158 526.7 0.2 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 EAX94189.1 - 1.9e-100 334.9 0.0 2.7e-100 334.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Lectin_leg-like PF03388.13 EAX94190.1 - 2.7e-17 62.9 0.0 5.3e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family EAV_GS PF01309.18 EAX94190.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein RPA_C PF08784.11 EAX94192.1 - 0.0009 19.9 0.0 0.0016 19.1 0.0 1.4 1 1 0 1 1 1 1 Replication protein A C terminal PqqD PF05402.12 EAX94192.1 - 0.043 14.1 0.5 12 6.3 0.0 2.2 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) PMT PF02366.18 EAX94193.1 - 5.3e-31 108.1 11.8 5.3e-31 108.1 11.8 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX94193.1 - 1.4e-20 73.7 19.4 1.4e-20 73.7 19.4 3.5 3 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase IF4E PF01652.18 EAX94194.1 - 1.3e-32 112.8 0.1 2.1e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.16 EAX94195.1 - 2.3e-17 63.3 27.3 2.9e-17 63.0 27.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAX94195.1 - 3.6e-12 46.6 33.5 9.8e-09 35.5 10.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family FapA PF03961.13 EAX94196.1 - 0.018 13.7 7.5 0.021 13.4 7.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF515 PF04415.12 EAX94196.1 - 0.071 11.5 8.4 0.085 11.2 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CLZ PF16526.5 EAX94196.1 - 0.28 11.6 5.7 0.21 12.0 1.7 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EAX94196.1 - 0.87 8.9 7.1 1 8.7 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med9 PF07544.13 EAX94196.1 - 0.99 9.5 9.2 4.8 7.3 5.5 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 EKAL PF17986.1 EAX94196.1 - 1.1 9.4 4.8 5.6 7.1 0.2 2.6 2 1 1 3 3 3 0 EMP3-KAHRP-like N-terminal domain C1_1 PF00130.22 EAX94197.1 - 0.14 12.1 8.6 0.34 10.8 8.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3H2C3 PF17122.5 EAX94197.1 - 0.95 9.6 9.3 2.2 8.4 9.3 1.7 1 0 0 1 1 1 0 Zinc-finger RNA_pol_I_A49 PF06870.12 EAX94198.1 - 0.0061 15.5 0.1 0.0089 14.9 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ank_2 PF12796.7 EAX94198.1 - 0.012 16.1 1.1 1.1 9.9 0.1 3.4 2 2 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94198.1 - 0.051 14.2 0.1 9.9 6.9 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94198.1 - 1.9 9.3 3.9 23 6.0 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat DUF1304 PF06993.12 EAX94199.1 - 2.3e-17 62.9 1.0 2.3e-17 62.9 1.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1304) SNARE PF05739.19 EAX94199.1 - 0.14 12.2 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 SNARE domain DUF3592 PF12158.8 EAX94199.1 - 0.96 9.5 2.8 0.42 10.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF2614 PF11023.8 EAX94199.1 - 1.3 9.1 5.5 0.23 11.6 1.5 1.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain CompInhib_SCIN PF11546.8 EAX94200.1 - 2.5e-06 27.5 0.9 3.3e-06 27.1 0.9 1.2 1 0 0 1 1 1 1 Staphylococcal complement inhibitor SCIN DUF4279 PF14106.6 EAX94200.1 - 0.00045 20.4 0.2 0.00052 20.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) DUF1798 PF08807.10 EAX94200.1 - 0.0051 16.9 2.6 0.0072 16.4 2.6 1.3 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) PspA_IM30 PF04012.12 EAX94200.1 - 0.0076 15.9 3.5 0.0093 15.6 3.5 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF848 PF05852.11 EAX94200.1 - 0.01 16.0 1.0 0.012 15.8 1.0 1.1 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) CR6_interact PF10147.9 EAX94200.1 - 0.051 13.3 4.4 0.076 12.7 4.5 1.3 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF501 PF04417.12 EAX94200.1 - 0.059 13.2 1.9 0.07 12.9 1.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF501) LppA PF16708.5 EAX94200.1 - 0.12 12.3 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium Latarcin PF10279.9 EAX94200.1 - 0.17 12.3 4.1 0.11 12.9 1.4 1.9 1 1 1 2 2 2 0 Latarcin precursor Histone_HNS PF00816.21 EAX94200.1 - 0.34 11.8 3.1 0.28 12.0 1.6 1.8 1 1 0 1 1 1 0 H-NS histone family TPR_2 PF07719.17 EAX94202.1 - 1.4e-11 43.6 2.7 2.1 8.7 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAX94202.1 - 7.7e-10 38.8 0.0 0.0033 17.5 0.0 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX94202.1 - 6.9e-08 32.9 0.8 0.016 15.7 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX94202.1 - 9e-08 32.2 11.2 0.097 12.9 0.4 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EAX94202.1 - 9.4e-08 31.6 7.4 2.1 8.3 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX94202.1 - 3.5e-05 23.9 0.0 0.29 11.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAX94202.1 - 0.0037 17.9 0.0 3.7 8.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAX94202.1 - 0.011 16.5 0.1 4.8 8.3 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAX94202.1 - 0.13 11.9 0.0 4.3 7.1 0.1 3.4 4 0 0 4 4 4 0 TPR repeat NMO PF03060.15 EAX94203.1 - 1.6e-69 234.9 3.8 4.1e-45 154.6 2.3 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EAX94203.1 - 1.2e-14 54.1 0.3 1.5e-07 30.8 0.6 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAX94203.1 - 3.9e-08 32.7 1.6 6.6e-08 31.9 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EAX94203.1 - 2.1e-07 30.5 0.5 3.3e-07 29.9 0.5 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EAX94203.1 - 4.6e-05 22.8 2.6 6.5e-05 22.3 2.5 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EAX94203.1 - 0.0017 17.9 0.3 0.0074 15.8 0.4 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.12 EAX94203.1 - 0.0038 16.4 0.3 0.0081 15.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF561) ZnuA PF01297.17 EAX94203.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic TMP-TENI PF02581.17 EAX94203.1 - 0.11 11.9 1.1 0.34 10.2 0.9 2.0 1 1 1 2 2 2 0 Thiamine monophosphate synthase PBD PF00786.28 EAX94203.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 P21-Rho-binding domain Glu_synthase PF01645.17 EAX94203.1 - 0.74 8.9 9.8 5.4 6.0 8.6 2.5 2 1 0 2 2 2 0 Conserved region in glutamate synthase zf-C3HC4_3 PF13920.6 EAX94204.1 - 5.9e-05 22.9 11.4 0.00014 21.7 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EAX94204.1 - 0.00048 20.0 5.7 0.00098 18.9 5.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EAX94204.1 - 0.0016 18.4 12.7 0.0036 17.2 12.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAX94204.1 - 0.002 17.9 11.9 0.002 17.9 11.9 1.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAX94204.1 - 0.0038 17.0 14.5 0.011 15.6 13.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) COG5 PF10392.9 EAX94204.1 - 0.012 15.8 5.5 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 YabA PF06156.13 EAX94204.1 - 0.025 15.2 8.1 0.8 10.4 0.9 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DASH_Duo1 PF08651.10 EAX94204.1 - 0.028 14.2 5.0 0.19 11.5 0.4 2.9 2 1 2 4 4 4 0 DASH complex subunit Duo1 DUF2443 PF10398.9 EAX94204.1 - 0.1 12.6 2.2 5.4 7.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Dna2 PF08696.11 EAX94204.1 - 0.38 10.5 4.3 0.94 9.3 0.4 2.4 1 1 1 2 2 2 0 DNA replication factor Dna2 zf-RING_10 PF16685.5 EAX94204.1 - 0.47 10.6 8.7 0.65 10.2 7.5 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 Flagellar_rod PF05149.12 EAX94204.1 - 0.73 9.2 12.8 0.98 8.8 4.5 2.9 1 1 2 3 3 3 0 Paraflagellar rod protein zf-C3HC4 PF00097.25 EAX94204.1 - 0.98 9.3 15.4 2.9 7.9 13.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Snapin_Pallidin PF14712.6 EAX94204.1 - 1.4 9.4 7.4 2.8 8.4 0.1 3.5 3 1 1 4 4 4 0 Snapin/Pallidin zf-RING_UBOX PF13445.6 EAX94204.1 - 1.9 8.5 14.8 0.088 12.9 6.4 2.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.6 EAX94204.1 - 2.9 7.8 11.4 1 9.2 8.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EAX94204.1 - 4.2 7.8 16.6 2.4 8.6 14.0 1.9 2 0 0 2 2 1 0 Ring finger domain Pro-NT_NN PF07421.11 EAX94205.1 - 0.011 16.0 0.9 0.011 16.0 0.9 1.0 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor MAJIN PF15077.6 EAX94205.1 - 3.8 7.2 8.7 3.9 7.2 8.7 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein FAS_N PF17828.1 EAX94206.1 - 0.006 16.6 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX94207.1 - 1.6e-07 30.6 0.6 3.1e-07 29.7 0.6 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2501 PF10696.9 EAX94208.1 - 0.077 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) rve PF00665.26 EAX94209.1 - 6.7e-12 45.7 0.1 1.2e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain LBR_tudor PF09465.10 EAX94209.1 - 0.00058 19.6 0.3 0.0014 18.3 0.3 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX94209.1 - 0.11 13.0 0.5 1.8 9.0 0.3 2.9 1 1 1 2 2 2 0 Spi protease inhibitor EpuA PF11772.8 EAX94210.1 - 0.0098 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta PTR PF12789.7 EAX94211.1 - 1.3e-08 34.8 10.2 0.00066 19.7 1.5 3.9 2 1 1 3 3 3 3 Phage tail repeat like Rab5-bind PF09311.11 EAX94211.1 - 0.0073 15.7 3.6 0.043 13.2 0.3 2.2 1 1 1 2 2 2 1 Rabaptin-like protein HIP1_clath_bdg PF16515.5 EAX94211.1 - 0.011 16.3 1.1 0.04 14.5 0.2 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MU2_FHA PF18221.1 EAX94211.1 - 0.068 13.2 0.2 1.6 8.8 0.2 2.5 1 1 1 2 2 2 0 Mutator 2 Fork head associated domain Fib_alpha PF08702.10 EAX94211.1 - 7.1 6.8 10.2 1.8 8.7 0.9 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pox_A32 PF04665.12 EAX94213.1 - 1.6e-07 31.1 0.0 2.2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX94216.1 - 3.9e-43 147.4 0.5 4.8e-43 147.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Tetraspanin PF00335.20 EAX94221.1 - 0.00054 19.7 11.6 0.0011 18.7 11.6 1.5 1 1 0 1 1 1 1 Tetraspanin family TRAP_alpha PF03896.16 EAX94222.1 - 0.00096 18.4 3.1 0.0014 17.9 3.1 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Pannexin_like PF12534.8 EAX94222.1 - 0.12 11.5 7.4 0.16 11.1 7.4 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CAC1F_C PF16885.5 EAX94222.1 - 0.34 10.5 8.2 0.46 10.1 8.2 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term AF-4 PF05110.13 EAX94222.1 - 0.48 8.5 21.3 0.59 8.2 21.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4338 PF14236.6 EAX94222.1 - 0.7 9.1 5.7 0.31 10.3 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4338) Presenilin PF01080.17 EAX94222.1 - 1.8 7.2 7.9 1.8 7.2 7.9 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EAX94222.1 - 2.1 8.8 11.3 3.7 8.0 11.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 EAX94222.1 - 4.4 6.4 8.1 5.1 6.2 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 EAX94222.1 - 7.7 5.2 12.2 9.1 5.0 12.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter F_bP_aldolase PF01116.20 EAX94223.1 - 7.5e-93 311.0 0.0 9.3e-93 310.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ABC1 PF03109.16 EAX94224.1 - 0.16 12.1 0.2 0.33 11.1 0.2 1.4 1 0 0 1 1 1 0 ABC1 family TFIIA PF03153.13 EAX94224.1 - 9.1 6.2 26.2 11 5.8 26.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4108 PF13390.6 EAX94225.1 - 2e-72 241.8 11.6 2.3e-72 241.6 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX94226.1 - 0.26 11.3 12.3 0.37 10.8 12.3 1.2 1 0 0 1 1 1 0 Glycine zipper PTR PF12789.7 EAX94228.1 - 4.2e-59 196.5 38.3 1.2e-34 118.2 16.3 5.0 4 1 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX94228.1 - 0.075 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EFhand_Ca_insen PF08726.10 EAX94229.1 - 0.017 15.2 0.1 0.058 13.5 0.1 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand SNF2_N PF00176.23 EAX94232.1 - 3e-42 144.6 0.1 1e-41 142.8 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX94232.1 - 1.9e-19 70.1 0.0 5.9e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAX94232.1 - 7.7e-09 35.8 4.0 9.2e-09 35.5 0.0 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAX94232.1 - 0.00077 18.7 0.1 0.0018 17.6 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EAX94232.1 - 0.0022 17.7 0.1 0.0083 15.8 0.1 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Ank_2 PF12796.7 EAX94233.1 - 6.9e-275 888.6 39.3 1.6e-18 67.1 0.0 20.9 4 4 19 24 24 24 24 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94233.1 - 5.8e-170 549.1 0.0 5.4e-08 33.0 0.0 29.4 7 5 26 34 34 34 34 Ankyrin repeats (many copies) Ank PF00023.30 EAX94233.1 - 1.7e-166 534.2 0.0 6.2e-05 23.3 0.0 39.3 40 0 0 40 40 40 34 Ankyrin repeat Ank_4 PF13637.6 EAX94233.1 - 7.8e-165 533.4 0.0 2.3e-09 37.6 0.0 25.3 15 7 13 30 30 30 27 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94233.1 - 4.7e-148 462.8 0.0 0.00034 20.8 0.0 38.1 40 0 0 40 40 38 33 Ankyrin repeat YfmQ PF10787.9 EAX94233.1 - 3.6e-09 36.5 7.0 2.6 7.8 0.1 12.1 5 4 7 14 14 14 1 Uncharacterised protein from bacillus cereus group CdAMP_rec PF06153.11 EAX94233.1 - 6.8e-05 23.0 9.5 2 8.6 0.1 9.8 8 3 4 12 12 12 1 Cyclic-di-AMP receptor Wzt_C PF14524.6 EAX94233.1 - 0.0071 16.4 0.2 39 4.2 0.0 5.2 6 0 0 6 6 6 0 Wzt C-terminal domain Cullin_binding PF03556.15 EAX94233.1 - 0.033 14.6 0.3 28 5.2 0.0 3.5 3 0 0 3 3 3 0 Cullin binding NLRC4_HD PF17889.1 EAX94233.1 - 0.052 13.9 0.2 0.5 10.7 0.2 2.8 1 0 0 1 1 1 0 NLRC4 helical domain Cyclin_N PF00134.23 EAX94233.1 - 0.12 12.1 0.0 6.8 6.5 0.0 3.6 3 1 0 3 3 3 0 Cyclin, N-terminal domain HJURP_mid PF12346.8 EAX94233.1 - 0.14 12.6 2.1 35 4.9 0.0 3.8 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat VraX PF17412.2 EAX94234.1 - 0.022 14.4 0.5 0.11 12.1 0.5 2.3 1 0 0 1 1 1 0 Family of unknown function Laminin_G_3 PF13385.6 EAX94234.1 - 0.023 14.9 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Snapin_Pallidin PF14712.6 EAX94235.1 - 0.064 13.7 0.4 3 8.3 0.0 2.9 2 1 2 4 4 4 0 Snapin/Pallidin KxDL PF10241.9 EAX94235.1 - 0.095 13.0 4.8 0.92 9.8 0.0 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein Dynactin_p22 PF07426.11 EAX94235.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.6 2 1 0 2 2 2 0 Dynactin subunit p22 GIDA_assoc PF13932.6 EAX94235.1 - 0.34 11.1 8.1 0.25 11.5 5.1 1.9 1 1 1 2 2 2 0 GidA associated domain YtxH PF12732.7 EAX94235.1 - 1.7 9.2 7.0 15 6.2 0.2 2.8 2 1 0 2 2 2 0 YtxH-like protein Acetyltransf_1 PF00583.25 EAX94236.1 - 2.6e-06 27.6 0.2 0.00011 22.4 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAX94236.1 - 0.0006 20.2 0.3 0.0031 17.9 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX94236.1 - 0.0087 16.0 0.0 0.058 13.4 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 EAX94236.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAX94236.1 - 0.035 14.1 0.2 0.25 11.3 0.2 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EAX94237.1 - 1.1e-38 133.1 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94237.1 - 1.2e-15 57.6 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94237.1 - 1.2e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EAX94237.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HEAT PF02985.22 EAX94238.1 - 0.0073 16.5 0.1 0.03 14.6 0.1 2.2 1 0 0 1 1 1 1 HEAT repeat TFCD_C PF12612.8 EAX94238.1 - 0.027 14.3 1.6 0.06 13.2 0.3 2.3 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal UME PF08064.13 EAX94238.1 - 0.03 14.2 0.2 0.49 10.3 0.2 3.0 2 2 1 3 3 3 0 UME (NUC010) domain Cnd1 PF12717.7 EAX94238.1 - 0.74 9.8 17.9 0.2 11.7 2.3 4.0 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAX94238.1 - 0.77 10.4 4.6 7.3 7.3 0.1 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Ank_4 PF13637.6 EAX94239.1 - 9e-34 115.4 2.1 7.3e-08 32.8 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94239.1 - 5.1e-32 110.3 0.7 1.2e-12 48.2 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94239.1 - 1.9e-29 101.4 1.3 5.8e-07 29.7 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94239.1 - 6.4e-27 90.6 2.1 0.00089 19.5 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EAX94239.1 - 7.3e-23 80.0 0.1 0.012 16.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat DUF3447 PF11929.8 EAX94239.1 - 3.8e-05 23.6 5.2 0.039 13.9 0.3 4.3 3 2 0 3 3 3 2 Domain of unknown function (DUF3447) Fe-ADH PF00465.19 EAX94240.1 - 5.9e-66 222.7 0.0 7.1e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX94240.1 - 4.2e-08 33.2 0.1 1.8e-06 27.9 0.0 2.4 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EAX94240.1 - 0.17 11.0 0.4 4.1 6.5 0.0 2.8 3 0 0 3 3 3 0 3-dehydroquinate synthase T5orf172 PF10544.9 EAX94241.1 - 2.5e-06 28.0 0.2 5.7e-06 26.8 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Pox_A32 PF04665.12 EAX94242.1 - 6.5e-08 32.3 1.1 7.8e-08 32.1 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX94242.1 - 0.0044 16.7 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX94242.1 - 0.05 13.3 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX94242.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Ribosomal_S2 PF00318.20 EAX94243.1 - 3.4e-32 111.4 0.7 2.8e-15 56.1 0.3 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.22 EAX94244.1 - 2e-14 53.5 0.0 3e-14 52.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAX94244.1 - 3.8e-14 52.9 0.7 2.1e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX94244.1 - 0.00037 20.6 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EAX94244.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_18 PF13238.6 EAX94244.1 - 0.044 14.3 0.2 0.12 13.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EAX94244.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 EAX94244.1 - 0.15 12.5 0.6 13 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF2120 PF09893.9 EAX94244.1 - 0.45 10.6 4.3 1.5 8.9 2.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) zf-RING_2 PF13639.6 EAX94245.1 - 1.3e-12 47.8 9.7 1.3e-12 47.8 9.7 2.5 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX94245.1 - 1.3e-10 41.0 9.8 1.3e-10 41.0 9.8 2.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX94245.1 - 5.6e-09 35.6 5.2 5.6e-09 35.6 5.2 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 EAX94245.1 - 1.4e-07 31.7 11.9 1.4e-07 31.7 11.9 3.3 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAX94245.1 - 2.2e-07 30.6 7.6 2.2e-07 30.6 7.6 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX94245.1 - 2.4e-06 27.3 9.6 2.4e-06 27.3 9.6 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX94245.1 - 1.4e-05 25.0 2.9 1.4e-05 25.0 2.9 3.1 4 0 0 4 4 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX94245.1 - 5.6e-05 23.0 8.5 5.6e-05 23.0 8.5 2.9 2 2 1 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAX94245.1 - 0.0003 20.8 6.6 0.0003 20.8 6.6 2.1 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EAX94245.1 - 0.00032 20.3 7.2 0.00032 20.3 7.2 2.0 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EAX94245.1 - 0.00054 19.8 7.0 0.00054 19.8 7.0 2.7 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAX94245.1 - 0.022 14.9 5.3 0.022 14.9 5.3 3.3 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 EAX94245.1 - 0.025 14.6 2.3 0.05 13.6 2.3 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.8 EAX94245.1 - 0.34 10.8 4.6 0.88 9.4 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-WRNIP1_ubi PF18279.1 EAX94245.1 - 0.45 11.3 4.7 3.7 8.4 0.7 3.1 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain RINGv PF12906.7 EAX94245.1 - 0.61 10.2 9.3 1.2 9.3 7.8 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.6 EAX94245.1 - 3.9 7.4 9.6 0.4 10.6 4.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EAX94245.1 - 6 6.8 17.3 4.5 7.1 0.1 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain RecR PF02132.15 EAX94245.1 - 6.1 6.5 13.1 7.8 6.1 0.2 4.0 3 1 0 3 3 3 0 RecR protein zf-HC5HC2H_2 PF13832.6 EAX94245.1 - 7.1 6.8 13.2 9.7 6.4 10.2 2.3 1 1 0 1 1 1 0 PHD-zinc-finger like domain DUF3245 PF11595.8 EAX94246.1 - 0.049 14.1 12.1 0.38 11.2 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) G-patch_2 PF12656.7 EAX94246.1 - 0.056 13.5 0.5 0.15 12.1 0.0 1.9 1 1 1 2 2 2 0 G-patch domain FAM177 PF14774.6 EAX94247.1 - 1.7e-09 38.0 1.2 2.8e-09 37.3 1.2 1.4 1 1 0 1 1 1 1 FAM177 family TraH PF06122.11 EAX94247.1 - 0.085 12.1 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Pkinase PF00069.25 EAX94248.1 - 4.2e-38 131.2 0.3 6e-38 130.7 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94248.1 - 2.6e-14 53.1 0.1 4.3e-14 52.4 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX94248.1 - 0.00026 21.0 0.1 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX94248.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX94248.1 - 0.019 13.8 0.0 0.072 11.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase EcKinase PF02958.20 EAX94248.1 - 0.019 14.3 0.4 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 EAX94248.1 - 0.067 12.8 0.3 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 RIO1 family AA_permease PF00324.21 EAX94249.1 - 2.3e-70 237.6 54.6 3e-70 237.2 54.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAX94249.1 - 8.8e-30 103.9 59.7 1.9e-29 102.8 59.7 1.4 1 1 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 EAX94250.1 - 1.3e-31 108.5 0.3 1.1e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94250.1 - 2.9e-24 85.1 1.2 2.8e-13 49.9 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX94250.1 - 7.9e-06 25.7 0.3 0.00061 19.6 0.3 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX94250.1 - 9.7e-05 22.4 0.2 0.032 14.3 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX94250.1 - 0.0034 17.6 0.6 0.0059 16.8 0.4 1.6 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rap1-DNA-bind PF09197.10 EAX94250.1 - 0.011 16.4 0.1 0.22 12.1 0.0 2.4 1 1 1 2 2 2 0 Rap1, DNA-binding GIY-YIG PF01541.24 EAX94250.1 - 0.018 15.3 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain Fn3_assoc PF13287.6 EAX94252.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Fn3 associated Beta_helix PF13229.6 EAX94253.1 - 0.003 17.4 16.6 0.0045 16.8 6.0 2.1 1 1 0 1 1 1 1 Right handed beta helix region Myb_DNA-binding PF00249.31 EAX94254.1 - 8.8e-28 96.2 0.1 1.2e-14 54.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94254.1 - 2e-22 79.2 0.8 5.9e-14 52.1 0.1 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX94254.1 - 9.3e-10 38.3 3.3 0.00029 20.7 0.1 2.7 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX94254.1 - 4.6e-07 29.8 4.4 0.00081 19.4 0.0 3.6 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EAX94254.1 - 0.0018 18.5 0.9 0.089 13.0 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 HEPN_SAV2148 PF18725.1 EAX94254.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN Myb_DNA-bind_2 PF08914.11 EAX94254.1 - 0.021 15.0 1.3 0.45 10.7 0.1 3.2 3 1 0 3 3 3 0 Rap1 Myb domain A2M PF00207.22 EAX94254.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin family EGF_Tenascin PF18720.1 EAX94256.1 - 0.6 10.2 3.5 1.1 9.4 3.5 1.4 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EAX94256.1 - 1.3 9.4 6.9 2.3 8.6 6.9 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.7 EAX94256.1 - 5.6 7.2 6.1 14 5.9 6.1 1.6 1 0 0 1 1 1 0 EGF domain TINF2_N PF14973.6 EAX94257.1 - 0.035 14.5 1.5 0.08 13.3 0.9 1.8 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF5531 PF17671.1 EAX94257.1 - 0.081 12.8 1.5 0.15 12.0 1.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Pkinase PF00069.25 EAX94258.1 - 2.1e-29 102.7 0.0 3.5e-29 102.0 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94258.1 - 1.6e-12 47.3 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4108 PF13390.6 EAX94259.1 - 7e-63 210.8 6.3 7.8e-63 210.7 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX94259.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein MULE PF10551.9 EAX94260.1 - 4.9e-11 42.9 1.7 7.4e-11 42.3 0.8 1.8 2 0 0 2 2 2 1 MULE transposase domain X8 PF07983.13 EAX94260.1 - 0.01 16.5 0.5 0.45 11.2 0.2 2.6 2 0 0 2 2 2 1 X8 domain L27_1 PF09058.10 EAX94260.1 - 0.052 13.5 5.3 0.23 11.5 0.0 3.6 3 1 0 3 3 3 0 L27_1 Transposase_mut PF00872.18 EAX94260.1 - 0.066 12.1 0.9 0.14 11.0 0.9 1.5 1 0 0 1 1 1 0 Transposase, Mutator family CREPT PF16566.5 EAX94260.1 - 0.083 13.1 5.5 0.18 12.0 0.2 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour PTR PF12789.7 EAX94261.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.6 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX94261.1 - 0.016 14.9 0.1 0.055 13.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAX94261.1 - 0.022 14.6 5.7 0.038 13.8 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EDR1 PF14381.6 EAX94261.1 - 0.088 12.5 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX94261.1 - 0.21 12.1 3.7 0.22 12.0 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX94261.1 - 9.7 5.7 20.8 4.2e+03 -2.9 20.8 3.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX94262.1 - 5.9e-16 58.7 3.3 8.8e-16 58.1 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAX94262.1 - 0.14 12.6 0.5 0.37 11.3 0.2 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Pox_A32 PF04665.12 EAX94263.1 - 6.8e-08 32.3 1.2 7.6e-08 32.1 1.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX94263.1 - 0.004 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX94263.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX94263.1 - 0.068 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) DUF4108 PF13390.6 EAX94264.1 - 2.2e-61 206.0 7.9 2.4e-61 205.8 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX94264.1 - 0.12 12.7 0.1 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Gly_rich PF12810.7 EAX94266.1 - 2.5e-26 93.1 7.7 3e-26 92.8 7.7 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX94267.1 - 0.0015 18.5 0.1 0.0018 18.2 0.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Chal_sti_synt_N PF00195.19 EAX94269.1 - 0.0042 16.5 0.8 0.0058 16.1 0.8 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX94270.1 - 1.8e-156 518.7 11.9 2.3e-156 518.4 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX94270.1 - 0.011 16.2 1.7 0.032 14.7 0.3 2.0 2 0 0 2 2 2 0 Fez1 DUF3549 PF12069.8 EAX94270.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) KELK PF15796.5 EAX94270.1 - 0.05 14.1 7.0 2.1 8.9 0.4 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX94270.1 - 0.13 12.2 1.0 0.33 10.8 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase ZapB PF06005.12 EAX94270.1 - 0.13 12.8 0.4 0.13 12.8 0.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB RNA_pol_Rpb1_5 PF04998.17 EAX94270.1 - 3.2 7.1 5.0 3.7 6.9 4.7 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2408 PF10303.9 EAX94270.1 - 3.7 8.1 6.4 0.72 10.4 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) YmgB PF10798.8 EAX94271.1 - 0.0085 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR EF-hand_10 PF14788.6 EAX94272.1 - 0.028 14.3 0.8 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 EF hand Fic PF02661.18 EAX94272.1 - 0.075 13.9 0.3 1.5 9.8 0.0 2.8 2 1 0 2 2 2 0 Fic/DOC family Zn_ribbon_2 PF12674.7 EAX94272.1 - 0.59 10.8 4.1 6.2 7.5 0.0 3.8 3 1 1 4 4 4 0 Putative zinc ribbon domain DNA_pol_B_2 PF03175.13 EAX94273.1 - 1e-06 27.9 1.5 1.8e-06 27.1 1.3 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Amnionless PF14828.6 EAX94274.1 - 0.045 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Amnionless FtsK_SpoIIIE_N PF12538.8 EAX94274.1 - 0.64 10.2 10.6 3.7 7.8 0.5 3.7 3 0 0 3 3 3 0 DNA transporter TPR_12 PF13424.6 EAX94275.1 - 1.7e-11 44.3 1.8 1.2e-05 25.5 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX94275.1 - 4.3e-05 23.3 2.8 0.91 9.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAX94275.1 - 4.5e-05 23.2 0.5 0.42 10.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX94275.1 - 0.001 18.7 0.2 1.2 8.8 0.1 2.7 2 0 0 2 2 2 2 TPR repeat MIT PF04212.18 EAX94275.1 - 0.0011 19.0 1.0 0.04 14.0 0.0 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EAX94275.1 - 0.0014 18.4 4.4 0.077 12.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX94275.1 - 0.0021 18.0 1.1 4.5 7.5 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX94275.1 - 0.0075 16.4 4.1 0.23 11.8 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EAX94275.1 - 0.01 15.6 6.2 0.019 14.7 2.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 EAX94275.1 - 0.082 13.8 1.1 1.3 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EAX94275.1 - 0.11 12.9 0.3 1.1 9.7 0.2 2.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EAX94275.1 - 0.13 13.0 3.0 17 6.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat EST1 PF10374.9 EAX94275.1 - 1.3 9.6 8.8 0.58 10.8 5.9 1.9 2 0 0 2 2 2 0 Telomerase activating protein Est1 Coilin_N PF15862.5 EAX94275.1 - 2.3 8.0 14.4 0.61 9.9 11.0 1.7 2 0 0 2 2 2 0 Coilin N-terminus LRR_5 PF13306.6 EAX94276.1 - 3.2e-24 85.3 22.1 1.5e-16 60.5 8.7 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EAX94276.1 - 7.9 6.7 11.3 52 4.1 6.7 4.0 3 1 0 3 3 3 0 FNIP Repeat UBA PF00627.31 EAX94277.1 - 0.00059 19.7 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain WASH-7_C PF14746.6 EAX94277.1 - 0.038 13.7 0.3 0.038 13.7 0.3 1.7 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal UBA_6 PF18039.1 EAX94277.1 - 0.093 12.7 0.1 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain zinc_ribbon_10 PF10058.9 EAX94279.1 - 0.87 9.4 6.1 2 8.2 6.1 1.6 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein XPC-binding PF09280.11 EAX94280.1 - 1.4 8.7 10.2 0.9 9.3 0.2 4.0 4 0 0 4 4 4 0 XPC-binding domain LRR_5 PF13306.6 EAX94281.1 - 1.1e-87 290.5 95.7 6.2e-24 84.4 12.7 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94281.1 - 1e-18 66.8 16.2 0.00043 20.0 0.1 9.3 5 3 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EAX94281.1 - 0.11 13.0 24.9 0.26 11.8 0.3 9.0 5 3 3 8 8 8 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 EAX94282.1 - 1.5e-06 28.8 3.2 0.24 12.3 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Sec16_C PF12931.7 EAX94282.1 - 0.00027 20.7 0.4 0.00076 19.2 0.0 2.0 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 Maelstrom PF13017.6 EAX94282.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 piRNA pathway germ-plasm component ubiquitin PF00240.23 EAX94284.1 - 7.9e-07 28.7 0.4 1.7e-06 27.7 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family RR_TM4-6 PF06459.12 EAX94284.1 - 0.00033 20.6 2.1 0.00044 20.2 2.1 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Rad60-SLD PF11976.8 EAX94284.1 - 0.00035 20.3 0.9 0.0013 18.5 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EAX94284.1 - 0.1 12.7 0.1 0.54 10.4 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LRR_5 PF13306.6 EAX94286.1 - 2.1e-38 131.2 4.3 2.6e-38 130.9 4.3 1.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94286.1 - 1.6e-05 24.6 0.0 0.024 14.4 0.0 2.7 1 1 2 3 3 3 3 Leucine rich repeat Peptidase_M8 PF01457.16 EAX94286.1 - 0.17 10.5 1.7 17 3.9 0.1 2.1 1 1 0 2 2 2 0 Leishmanolysin L27_1 PF09058.10 EAX94288.1 - 0.0091 16.0 4.3 0.12 12.4 0.0 3.2 2 1 0 2 2 2 1 L27_1 CREPT PF16566.5 EAX94288.1 - 0.045 13.9 1.0 0.1 12.8 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAX94288.1 - 0.099 12.7 0.8 0.36 10.9 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAX94288.1 - 0.73 10.0 7.2 0.45 10.7 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PSP PF04046.16 EAX94289.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94290.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX94291.1 - 0.042 14.3 0.6 0.091 13.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX94292.1 - 2.5e-27 94.7 10.9 2.5e-27 94.7 10.9 4.5 6 0 0 6 6 6 1 Phage tail repeat like Imm32 PF15566.6 EAX94292.1 - 1.1 9.1 3.9 6 6.7 0.7 2.9 1 1 1 2 2 2 0 Immunity protein 32 DUF240 PF03086.14 EAX94292.1 - 4.4 7.2 10.1 1.6 8.7 0.4 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF240) DUF2939 PF11159.8 EAX94294.1 - 0.016 15.6 0.5 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94294.1 - 0.87 9.6 5.8 0.93 9.5 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAX94294.1 - 1.1 8.2 2.7 1.2 8.1 2.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein GatB_Yqey PF02637.18 EAX94296.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 GatB domain C2 PF00168.30 EAX94297.1 - 0.014 15.6 0.0 0.018 15.3 0.0 1.3 1 1 0 1 1 1 0 C2 domain ODV-E18 PF10717.9 EAX94298.1 - 0.0024 17.7 0.2 0.0043 16.9 0.2 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 CDC45 PF02724.14 EAX94298.1 - 0.0066 14.8 9.7 0.0095 14.3 9.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Orf78 PF06024.12 EAX94298.1 - 0.0099 16.2 5.1 0.078 13.3 5.0 2.4 1 1 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 EAX94298.1 - 0.014 14.8 0.3 0.014 14.8 0.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5305) LAP1C PF05609.12 EAX94298.1 - 0.019 14.1 6.8 0.026 13.6 6.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LRRC37AB_C PF14914.6 EAX94298.1 - 0.026 14.4 1.3 0.077 12.9 1.3 1.9 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain BSMAP PF12280.8 EAX94298.1 - 0.029 14.6 0.1 0.064 13.5 0.1 1.7 1 0 0 1 1 1 0 Brain specific membrane anchored protein Connexin PF00029.19 EAX94298.1 - 0.062 13.1 2.0 0.13 12.0 2.0 1.5 1 1 0 1 1 1 0 Connexin DUF3169 PF11368.8 EAX94298.1 - 0.065 12.7 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Sigma_reg_N PF13800.6 EAX94298.1 - 0.069 13.4 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SARAF PF06682.12 EAX94298.1 - 0.073 12.7 0.3 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Zip PF02535.22 EAX94298.1 - 0.11 11.7 1.2 0.2 10.8 1.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 EAX94298.1 - 0.13 12.3 3.9 0.23 11.4 3.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 EAX94298.1 - 0.22 9.6 8.0 0.17 10.0 6.3 1.6 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CrgA PF06781.12 EAX94298.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.2 1 1 1 2 2 2 0 Cell division protein CrgA RNA_pol_Rpc4 PF05132.14 EAX94298.1 - 0.36 11.2 7.8 0.86 10.0 7.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 EphA2_TM PF14575.6 EAX94298.1 - 0.93 10.4 0.0 0.93 10.4 0.0 2.2 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.6 EAX94298.1 - 1 9.4 8.3 7 6.7 8.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4448 PF14610.6 EAX94298.1 - 1.1 9.0 9.7 3.8 7.2 5.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) DNA_pol_phi PF04931.13 EAX94298.1 - 1.7 6.7 14.2 2.5 6.1 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4834 PF16118.5 EAX94298.1 - 2.5 9.1 10.0 4.4 8.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3377 PF11857.8 EAX94298.1 - 4 7.4 8.9 36 4.4 8.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) PBP1_TM PF14812.6 EAX94298.1 - 5.4 7.4 17.6 2.8 8.4 13.4 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Insulin_TMD PF17870.1 EAX94299.1 - 0.00094 19.2 4.0 0.0019 18.2 4.0 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Endomucin PF07010.12 EAX94299.1 - 0.0011 19.0 5.6 0.0016 18.5 5.6 1.3 1 0 0 1 1 1 1 Endomucin Orf78 PF06024.12 EAX94299.1 - 0.0016 18.7 1.3 0.0049 17.1 1.3 1.9 1 1 0 1 1 1 1 Orf78 (ac78) SID-1_RNA_chan PF13965.6 EAX94299.1 - 0.0031 16.0 0.6 0.0031 16.0 0.6 1.7 1 1 1 2 2 2 1 dsRNA-gated channel SID-1 Amnionless PF14828.6 EAX94299.1 - 0.0035 16.2 0.0 0.0048 15.8 0.0 1.1 1 0 0 1 1 1 1 Amnionless Syndecan PF01034.20 EAX94299.1 - 0.0043 16.9 0.8 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 Syndecan domain RIFIN PF02009.16 EAX94299.1 - 0.0048 16.8 0.4 0.0066 16.4 0.4 1.3 1 0 0 1 1 1 1 Rifin DUF4064 PF13273.6 EAX94299.1 - 0.0054 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF5383 PF17355.2 EAX94299.1 - 0.015 15.7 3.9 0.041 14.3 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5383) LRRC37AB_C PF14914.6 EAX94299.1 - 0.025 14.5 1.0 0.048 13.6 0.7 1.6 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF3328 PF11807.8 EAX94299.1 - 0.025 14.4 0.7 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Tmemb_9 PF05434.11 EAX94299.1 - 0.04 13.8 0.1 0.04 13.8 0.1 1.7 2 0 0 2 2 2 0 TMEM9 Baculo_11_kDa PF06143.11 EAX94299.1 - 0.051 13.1 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Sigma_reg_N PF13800.6 EAX94299.1 - 0.057 13.7 0.6 0.19 12.1 0.6 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EphA2_TM PF14575.6 EAX94299.1 - 0.085 13.7 0.0 0.21 12.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 EAX94299.1 - 0.091 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Synaptobrevin Cytadhesin_P30 PF07271.11 EAX94299.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Chordopox_A13L PF05961.11 EAX94299.1 - 0.13 12.5 0.9 0.53 10.6 0.9 2.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein LRR19-TM PF15176.6 EAX94299.1 - 0.23 11.5 4.4 0.66 10.0 0.1 2.8 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain FeoB_associated PF12669.7 EAX94299.1 - 0.23 11.9 3.5 0.44 11.0 3.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TMEM154 PF15102.6 EAX94299.1 - 0.25 11.2 8.9 0.33 10.9 7.4 2.0 1 1 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 EAX94299.1 - 1.2 9.4 2.5 2.2 8.5 2.5 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ABC2_membrane_3 PF12698.7 EAX94299.1 - 6.5 5.8 7.4 0.31 10.1 1.4 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Myb_DNA-binding PF00249.31 EAX94301.1 - 7.3e-29 99.7 0.8 5.5e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94301.1 - 8.8e-26 89.9 2.4 2.7e-16 59.6 0.5 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX94301.1 - 1.6e-07 31.3 0.2 0.019 15.0 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX94301.1 - 9.9e-05 22.2 0.2 0.00083 19.2 0.1 2.0 1 1 1 2 2 2 1 Myb DNA-binding like Spore_III_AB PF09548.10 EAX94301.1 - 0.016 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_5 PF13873.6 EAX94301.1 - 0.018 15.1 4.9 3.2 7.9 0.0 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain XH PF03469.14 EAX94301.1 - 0.018 14.9 0.1 0.52 10.2 0.0 2.1 1 1 1 2 2 2 0 XH domain Myb_DNA-bind_2 PF08914.11 EAX94301.1 - 0.031 14.5 0.1 0.88 9.8 0.1 2.6 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX94301.1 - 0.05 14.0 3.9 0.65 10.4 0.4 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain ScdA_N PF04405.14 EAX94302.1 - 3.2e-20 71.5 0.2 5.6e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) Hemerythrin PF01814.23 EAX94302.1 - 1e-15 58.5 0.1 3.9e-15 56.6 0.1 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Pkinase PF00069.25 EAX94303.1 - 1.4e-56 191.8 0.1 1.7e-56 191.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94303.1 - 5.1e-38 130.8 0.0 6.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94303.1 - 1.1e-09 38.0 0.0 5.6e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAX94303.1 - 3.6e-05 22.7 0.0 5.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX94303.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAX94303.1 - 0.014 15.4 0.0 0.055 13.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAX94303.1 - 0.034 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX94303.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Dam1 PF08653.10 EAX94305.1 - 0.15 11.9 0.0 1 9.2 0.0 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 I_LWEQ PF01608.17 EAX94306.1 - 3.9e-08 33.7 7.2 3.9e-08 33.7 7.2 4.7 4 1 0 4 4 4 1 I/LWEQ domain RII_binding_1 PF10522.9 EAX94306.1 - 1.7 9.1 6.3 1.5 9.3 0.5 4.0 3 0 0 3 3 3 0 RII binding domain DUF5327 PF17261.2 EAX94306.1 - 2.1 9.2 10.8 1.6 9.5 0.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Ribosomal_L5e PF17144.4 EAX94307.1 - 7.4e-70 234.2 1.2 1.5e-69 233.2 1.2 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EAX94307.1 - 1.2e-24 87.0 9.3 1.2e-24 87.0 9.3 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF2853 PF11015.8 EAX94307.1 - 0.057 14.1 0.7 0.057 14.1 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) DUF4604 PF15377.6 EAX94307.1 - 2 8.8 10.3 3.7 7.9 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Cpn60_TCP1 PF00118.24 EAX94308.1 - 3.9e-152 507.3 0.2 4.4e-152 507.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 EAX94308.1 - 0.023 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator Pkr1 PF08636.10 EAX94309.1 - 5.2e-12 45.7 5.9 6.7e-12 45.4 5.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2512 PF10710.9 EAX94309.1 - 0.0032 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2512) YfhO PF09586.10 EAX94309.1 - 0.012 13.9 0.1 0.012 13.9 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Herpes_LMP1 PF05297.11 EAX94309.1 - 0.025 13.8 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2101 PF09874.9 EAX94309.1 - 0.029 14.1 1.7 0.032 13.9 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF808 PF05661.12 EAX94309.1 - 0.086 11.9 0.6 0.1 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Ank PF00023.30 EAX94310.1 - 2e-17 62.7 3.7 1.1e-06 28.8 0.5 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX94310.1 - 3.9e-17 62.4 0.1 2.9e-08 34.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94310.1 - 2.1e-15 57.1 4.1 5.8e-15 55.6 4.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94310.1 - 1.1e-14 53.1 1.3 6.1e-06 26.2 0.2 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX94310.1 - 4.4e-12 46.0 4.0 1.6e-09 37.8 1.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ThiS-like PF14453.6 EAX94310.1 - 0.0017 18.4 0.3 0.88 9.7 0.0 2.3 1 1 1 2 2 2 2 ThiS-like ubiquitin DUF4100 PF13352.6 EAX94310.1 - 0.003 17.4 0.2 0.0032 17.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4100) DUF3447 PF11929.8 EAX94311.1 - 9.3e-39 131.2 6.8 9.3e-39 131.2 6.8 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX94311.1 - 3.1e-25 88.2 2.2 3.4e-08 33.9 0.0 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94311.1 - 3.6e-21 75.6 9.0 8.1e-15 55.2 1.9 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94311.1 - 1.1e-20 73.0 2.2 5e-07 29.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX94311.1 - 1.5e-17 61.9 7.1 7.8e-05 22.8 0.1 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX94311.1 - 3.6e-16 59.0 1.0 1.1e-11 44.7 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94313.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Cpn60_TCP1 PF00118.24 EAX94314.1 - 9.9e-67 225.6 0.0 1.1e-66 225.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 EAX94315.1 - 2.5e-62 211.1 0.0 3.1e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family XisI PF08869.11 EAX94315.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 XisI protein FAM76 PF16046.5 EAX94317.1 - 0.0016 17.8 4.9 0.002 17.6 4.9 1.1 1 0 0 1 1 1 1 FAM76 protein DUF3802 PF12290.8 EAX94317.1 - 0.0018 18.8 1.4 0.0031 18.0 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3802) ARA70 PF12489.8 EAX94317.1 - 0.0037 17.5 2.0 0.094 12.9 1.3 2.1 1 1 1 2 2 2 2 Nuclear coactivator KASH_CCD PF14662.6 EAX94317.1 - 0.013 15.3 9.0 0.018 14.9 4.0 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SPATA24 PF15175.6 EAX94317.1 - 0.019 14.9 6.6 0.029 14.3 6.0 1.6 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 Sec2p PF06428.11 EAX94317.1 - 0.02 14.8 3.8 0.02 14.8 3.8 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3461 PF11944.8 EAX94317.1 - 0.028 14.5 1.5 0.028 14.5 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF4472 PF14739.6 EAX94317.1 - 0.032 15.0 7.1 0.053 14.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) kleA_kleC PF17383.2 EAX94317.1 - 0.054 13.8 0.6 0.14 12.5 0.1 1.9 3 0 0 3 3 2 0 Uncharacterized KorC regulated protein A Fib_alpha PF08702.10 EAX94317.1 - 0.1 12.8 5.2 0.16 12.1 5.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PRP1_N PF06424.12 EAX94317.1 - 0.1 13.0 3.0 0.14 12.5 3.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal ATG16 PF08614.11 EAX94317.1 - 0.17 12.1 8.7 0.25 11.5 8.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 EAX94317.1 - 0.26 11.2 10.4 1.4 8.8 5.8 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4404 PF14357.6 EAX94317.1 - 0.27 11.9 4.0 19 6.0 2.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CC2-LZ PF16516.5 EAX94317.1 - 0.8 10.1 8.3 2.1 8.8 3.5 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Pox_A_type_inc PF04508.12 EAX94317.1 - 2.8 7.9 5.6 8.5 6.4 0.2 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Abhydrolase_6 PF12697.7 EAX94318.1 - 1.5e-19 71.5 0.0 1.8e-19 71.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAX94318.1 - 7.7e-10 38.4 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAX94318.1 - 9.7e-05 22.6 0.0 0.00035 20.7 0.0 1.8 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 EAX94318.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EAX94318.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ank_2 PF12796.7 EAX94319.1 - 7.5e-31 106.6 1.7 8.3e-13 48.7 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94319.1 - 2.8e-30 104.3 2.7 1.8e-09 37.9 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94319.1 - 1.3e-28 98.7 0.8 3.4e-08 33.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX94319.1 - 4.1e-22 77.6 0.4 0.00077 19.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX94319.1 - 2.2e-19 67.5 0.1 0.0069 16.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Membralin PF09746.9 EAX94319.1 - 0.045 12.8 10.0 0.057 12.5 10.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein OmpH PF03938.14 EAX94319.1 - 0.31 11.4 19.7 0.49 10.7 19.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vfa1 PF08432.10 EAX94319.1 - 0.57 10.5 15.1 0.98 9.7 15.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NDT80_PhoG PF05224.12 EAX94319.1 - 0.58 10.3 9.6 1.1 9.4 9.6 1.4 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family SnAPC_2_like PF11035.8 EAX94319.1 - 0.97 9.5 7.1 2 8.5 7.1 1.5 1 1 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb HemX PF04375.14 EAX94319.1 - 1.7 7.8 15.2 2.4 7.4 15.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4407 PF14362.6 EAX94319.1 - 2.7 7.3 9.6 5.2 6.3 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MDM31_MDM32 PF08118.11 EAX94319.1 - 4.5 5.8 13.4 6.1 5.4 13.4 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins RP-C_C PF11800.8 EAX94319.1 - 5.9 6.9 7.8 8.9 6.3 7.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region ALMT PF11744.8 EAX94319.1 - 8.7 5.1 9.2 12 4.6 9.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Nckap1 PF09735.9 EAX94320.1 - 3.7e-09 35.2 5.4 1e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 Membrane-associated apoptosis protein POR_N PF01855.19 EAX94321.1 - 6.4e-58 196.2 0.2 1e-57 195.5 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EAX94321.1 - 3.4e-23 82.6 0.0 6e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EAX94321.1 - 8.8e-14 51.7 0.0 3.1e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 EAX94321.1 - 4.1e-07 30.5 8.0 1.3e-06 28.9 8.0 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EAX94321.1 - 4.3e-07 29.5 9.8 0.0028 17.4 2.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EAX94321.1 - 7.6e-07 30.0 6.4 0.002 19.0 0.9 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EAX94321.1 - 4.6e-06 26.7 9.7 4.9e-06 26.6 7.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAX94321.1 - 1.1e-05 25.7 7.3 4.3e-05 23.9 7.2 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAX94321.1 - 3e-05 24.0 9.0 6.6e-05 22.9 7.8 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Transketolase_C PF02780.20 EAX94321.1 - 5.7e-05 23.0 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fer4_21 PF14697.6 EAX94321.1 - 0.00014 21.9 11.4 0.00014 21.9 11.4 2.6 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAX94321.1 - 0.00015 21.7 13.6 0.00076 19.4 4.1 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain EKR PF10371.9 EAX94321.1 - 0.0011 18.7 0.0 0.0047 16.7 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function Fer4_2 PF12797.7 EAX94321.1 - 0.019 15.0 3.2 0.019 15.0 3.2 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain RapA_C PF12137.8 EAX94321.1 - 0.028 13.4 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Fer4_17 PF13534.6 EAX94321.1 - 0.064 13.8 13.9 0.55 10.8 13.2 2.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Gly-zipper_Omp PF13488.6 EAX94323.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX94323.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX94323.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX94323.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94323.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PSP PF04046.16 EAX94324.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94325.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX94328.1 - 1.9e-156 518.6 12.9 2.4e-156 518.3 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX94328.1 - 0.084 13.3 2.1 0.13 12.7 0.3 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX94328.1 - 0.55 10.7 6.7 2.4 8.7 0.7 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX94328.1 - 0.68 10.5 6.4 0.38 11.3 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX94329.1 - 0.027 14.9 0.6 0.052 14.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SPC25 PF06703.11 EAX94330.1 - 4.6e-14 52.5 6.0 5.2e-14 52.4 6.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-RING_2 PF13639.6 EAX94331.1 - 2e-13 50.4 38.3 9.8e-08 32.2 16.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-ANAPC11 PF12861.7 EAX94331.1 - 1.4e-08 34.7 18.8 1.8e-05 24.7 5.8 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EAX94331.1 - 2.5e-08 33.7 36.5 0.0005 20.0 15.9 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAX94331.1 - 9.6e-07 28.7 28.1 0.00067 19.6 8.8 3.5 2 2 2 4 4 4 2 RING-type zinc-finger zf-rbx1 PF12678.7 EAX94331.1 - 8.9e-06 25.9 29.1 0.00051 20.3 12.9 2.6 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EAX94331.1 - 3.7e-05 23.4 29.2 0.015 15.1 14.5 2.5 2 1 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EAX94331.1 - 4.5e-05 23.1 28.4 0.0002 21.0 10.7 3.0 3 0 0 3 3 3 2 RING-like zinc finger IQ PF00612.27 EAX94331.1 - 0.00019 20.9 3.2 0.00068 19.2 3.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4 PF00097.25 EAX94331.1 - 0.00044 20.1 40.6 0.0065 16.3 17.6 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX94331.1 - 0.00069 19.4 36.3 0.1 12.4 15.3 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAX94331.1 - 0.014 15.0 29.3 0.3 10.8 12.5 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EAX94331.1 - 0.32 10.9 40.1 8.6 6.3 17.3 3.6 2 2 2 4 4 4 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EAX94331.1 - 0.86 9.5 6.7 8.8 6.3 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif COX5B PF01215.19 EAX94331.1 - 0.98 9.1 4.6 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb WD40 PF00400.32 EAX94332.1 - 1.7e-26 91.9 2.7 0.00026 21.7 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94332.1 - 2.4e-13 50.2 0.6 0.23 11.8 0.0 5.7 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX94332.1 - 2.5e-07 30.8 0.1 4.9e-05 23.3 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EAX94332.1 - 2.2e-06 27.4 1.0 0.58 10.2 0.1 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EAX94332.1 - 0.00055 19.4 0.8 0.17 11.2 1.9 2.3 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EAX94332.1 - 0.00074 18.6 0.1 0.078 11.9 0.1 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EAX94332.1 - 0.0092 15.3 0.1 2 7.7 0.0 3.0 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF3091 PF11291.8 EAX94332.1 - 0.0096 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3091) DUF4566 PF15130.6 EAX94332.1 - 0.079 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Guanylate_kin PF00625.21 EAX94333.1 - 2.8e-54 183.6 0.1 3.2e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 EAX94333.1 - 0.0053 16.7 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EAX94333.1 - 0.008 16.3 2.5 0.38 10.9 2.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX94333.1 - 0.052 13.9 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EAX94333.1 - 0.055 14.0 0.1 0.12 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EAX94333.1 - 0.075 12.7 1.9 1.3 8.7 1.9 2.2 1 1 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 EAX94333.1 - 0.079 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EAX94333.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter LRR_6 PF13516.6 EAX94336.1 - 1.2e-16 59.2 33.8 0.0004 20.2 1.0 12.1 14 0 0 14 14 14 4 Leucine Rich repeat LRR_4 PF12799.7 EAX94336.1 - 0.00028 21.2 17.9 3.9 8.0 5.1 7.4 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX94336.1 - 0.014 15.9 5.7 38 5.4 0.1 7.7 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 EAX94336.1 - 1.3 8.9 18.9 1.2 8.9 2.0 7.3 8 3 0 8 8 8 0 Leucine rich repeat Jnk-SapK_ap_N PF09744.9 EAX94336.1 - 4.7 7.4 41.0 0.62 10.3 13.1 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 RNase_PH PF01138.21 EAX94337.1 - 9.2e-19 68.3 0.0 2e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Stomoxyn PF11585.8 EAX94337.1 - 0.14 12.2 0.1 3.2 7.8 0.0 2.5 1 1 1 2 2 2 0 Insect antimicrobial peptide, stomoxyn Ank_4 PF13637.6 EAX94338.1 - 9.3e-54 179.2 14.7 3e-12 46.8 0.1 8.8 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94338.1 - 9.5e-53 176.7 22.6 3.9e-15 56.2 0.5 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94338.1 - 7.1e-52 171.7 12.8 8.7e-08 32.3 0.1 9.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 EAX94338.1 - 3.8e-46 149.7 12.7 8.6e-06 25.7 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX94338.1 - 6.7e-40 134.6 14.4 1.8e-09 37.7 0.1 6.8 3 1 5 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94338.1 - 4e-22 77.9 7.8 4e-22 77.9 7.8 3.1 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX94338.1 - 0.0076 16.5 0.1 4.8 7.5 0.1 3.1 1 1 2 3 3 3 1 Pleckstrin homology domain Ntox33 PF15533.6 EAX94338.1 - 0.023 15.2 9.6 22 5.6 0.0 5.8 4 2 2 6 6 6 0 Bacterial toxin 33 Endonuc-dimeris PF09124.10 EAX94338.1 - 0.023 14.8 5.6 22 5.3 0.1 5.4 5 1 1 6 6 6 0 T4 recombination endonuclease VII, dimerisation Arc_PepC PF06819.11 EAX94339.1 - 0.067 13.3 0.8 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain THOC7 PF05615.13 EAX94340.1 - 0.33 11.2 6.8 0.77 10.0 6.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Pkinase PF00069.25 EAX94341.1 - 5.2e-32 111.2 0.0 6.6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94341.1 - 1.1e-16 60.9 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX94341.1 - 2.8e-09 36.3 0.0 3.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX94341.1 - 3.1e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX94341.1 - 6.9e-05 22.9 0.0 0.00038 20.4 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX94341.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAX94341.1 - 0.1 11.9 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DUF3447 PF11929.8 EAX94342.1 - 1.7e-39 133.6 9.0 2.9e-39 132.9 5.7 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94342.1 - 7e-25 87.4 1.7 5.6e-18 65.3 0.3 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94342.1 - 3.5e-20 72.1 2.0 2.3e-10 40.8 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94342.1 - 3.9e-19 68.2 0.6 1.5e-09 37.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAX94342.1 - 3e-17 61.0 4.9 4.3e-07 29.7 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX94342.1 - 1.7e-11 44.1 0.1 2.5e-08 34.0 0.0 3.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX94342.1 - 0.004 16.9 3.4 0.24 11.1 1.8 2.2 1 1 1 2 2 2 2 Shigella flexneri OspC protein WPP PF13943.6 EAX94342.1 - 0.076 13.4 0.1 6.1 7.3 0.0 2.2 1 1 1 2 2 2 0 WPP domain Ank_5 PF13857.6 EAX94343.1 - 3.7e-22 78.1 1.5 3e-07 30.6 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX94343.1 - 6.3e-21 74.5 0.0 1.4e-10 41.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94343.1 - 1e-20 74.1 0.1 7.9e-09 36.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94343.1 - 5.5e-20 69.3 0.1 0.0052 17.2 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX94343.1 - 3.4e-18 65.2 0.3 0.00025 21.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat DUF1706 PF08020.11 EAX94343.1 - 0.025 14.5 4.0 1.1 9.2 0.0 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1706) Peptidase_M16 PF00675.20 EAX94343.1 - 0.073 13.0 7.4 2.9 7.8 0.0 3.2 2 1 1 3 3 3 0 Insulinase (Peptidase family M16) UPF0061 PF02696.14 EAX94343.1 - 0.92 8.2 5.1 1.5 7.5 5.1 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family NDUFB10 PF10249.9 EAX94343.1 - 2 8.9 9.1 0.95 10.0 5.8 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Cons_hypoth698 PF03601.14 EAX94344.1 - 5.3e-55 186.4 14.5 6.4e-55 186.2 14.5 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 YwiC PF14256.6 EAX94344.1 - 0.045 14.1 0.1 0.045 14.1 0.1 3.7 5 0 0 5 5 5 0 YwiC-like protein DUF373 PF04123.13 EAX94344.1 - 0.71 9.2 12.1 1.4 8.3 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF373) NPAT_C PF15712.5 EAX94344.1 - 2.6 6.6 4.1 3.5 6.2 4.1 1.1 1 0 0 1 1 1 0 NPAT C terminus DUF4191 PF13829.6 EAX94344.1 - 3.3 7.0 6.3 1.6 8.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Pkinase PF00069.25 EAX94345.1 - 1.6e-12 47.4 0.5 4.2e-10 39.4 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94345.1 - 0.0046 16.3 0.1 0.17 11.1 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EAX94346.1 - 1.1e-57 195.4 0.0 1.5e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94346.1 - 4.2e-40 137.7 0.0 5.4e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94346.1 - 1e-07 31.6 0.0 4.1e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX94346.1 - 0.0061 15.7 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAX94346.1 - 0.026 13.3 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX94346.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4407 PF14362.6 EAX94348.1 - 0.00078 18.9 6.5 0.00078 18.9 6.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4407) YtxH PF12732.7 EAX94348.1 - 0.017 15.7 11.5 2 9.0 0.2 4.9 3 2 1 4 4 4 0 YtxH-like protein Phi-29_GP4 PF05464.11 EAX94348.1 - 0.28 11.5 4.1 0.3 11.4 1.0 2.7 2 1 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Ank_2 PF12796.7 EAX94349.1 - 9e-91 298.6 16.5 9.2e-20 71.0 0.3 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94349.1 - 2.8e-55 184.0 0.0 4.4e-12 46.3 0.0 5.8 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX94349.1 - 9.1e-53 174.5 0.2 1.1e-05 25.6 0.0 9.6 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 EAX94349.1 - 1.9e-45 147.6 0.5 0.00074 19.8 0.1 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 EAX94349.1 - 7.3e-43 144.1 3.6 8.8e-06 25.9 0.0 9.3 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Phage_holin_5_2 PF16079.5 EAX94349.1 - 2e-05 24.8 0.1 16 5.9 0.0 4.9 3 1 1 4 4 4 2 Phage holin family Hol44, in holin superfamily V DUF1897 PF09005.10 EAX94349.1 - 0.0057 16.1 0.1 1.3e+02 2.2 0.0 5.5 7 0 0 7 7 7 0 Domain of unknown function (DUF1897) Cass2 PF14526.6 EAX94349.1 - 0.088 13.0 2.5 0.75 10.0 0.1 3.2 4 0 0 4 4 4 0 Integron-associated effector binding protein Ras PF00071.22 EAX94350.1 - 0.0066 16.1 1.1 0.16 11.5 0.0 3.3 3 1 0 3 3 3 1 Ras family Pkinase PF00069.25 EAX94352.1 - 2.8e-51 174.4 0.1 3.6e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94352.1 - 2.1e-25 89.5 0.0 2.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94352.1 - 1e-07 31.6 0.0 2.5e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX94352.1 - 8.3e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S13 PF00416.22 EAX94353.1 - 1.3 9.4 7.4 4.8 7.6 1.4 4.2 3 0 0 3 3 3 0 Ribosomal protein S13/S18 DUF563 PF04577.14 EAX94354.1 - 0.015 15.5 0.0 0.026 14.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF563) PS_pyruv_trans PF04230.13 EAX94354.1 - 0.12 12.3 2.1 0.14 12.0 0.4 1.9 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase DUF3301 PF11743.8 EAX94354.1 - 0.12 12.1 0.2 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) TBCA PF02970.16 EAX94355.1 - 1.9e-16 60.2 5.3 2.3e-16 59.9 5.3 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2120 PF09893.9 EAX94355.1 - 0.043 13.9 1.0 0.055 13.6 1.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) AbiH PF14253.6 EAX94355.1 - 0.1 12.5 3.7 0.1 12.5 3.7 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH HSP70 PF00012.20 EAX94355.1 - 0.26 9.4 5.9 0.27 9.4 5.9 1.0 1 0 0 1 1 1 0 Hsp70 protein MCC-bdg_PDZ PF10506.9 EAX94356.1 - 0.33 11.0 4.2 15 5.7 0.7 3.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HALZ PF02183.18 EAX94356.1 - 1.1 9.5 16.9 6.5 7.1 1.5 5.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper NEMO PF11577.8 EAX94356.1 - 2.3 8.3 12.0 0.37 10.8 2.6 3.7 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO LRR_5 PF13306.6 EAX94357.1 - 5.2e-68 226.9 39.7 2.9e-22 79.0 3.8 4.3 2 1 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94357.1 - 2.4e-13 49.6 8.7 0.084 12.7 0.0 7.0 6 1 1 7 7 7 4 Leucine rich repeat Ig_mannosidase PF17753.1 EAX94357.1 - 0.086 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Ig-fold domain LRR_4 PF12799.7 EAX94357.1 - 0.099 13.1 21.1 3.6 8.2 0.0 7.2 5 3 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94358.1 - 1.7e-30 105.6 11.6 1.8e-16 60.3 2.0 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94358.1 - 6.6e-10 38.6 0.0 0.0094 15.7 0.0 3.8 4 0 0 4 4 4 3 Leucine rich repeat ATG16 PF08614.11 EAX94359.1 - 0.00028 21.2 21.1 0.00041 20.7 21.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 EAX94359.1 - 0.00055 20.0 18.5 0.0054 16.8 9.5 2.9 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 CEP63 PF17045.5 EAX94359.1 - 0.00065 19.7 8.7 0.00065 19.7 8.7 2.1 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa HMMR_N PF15905.5 EAX94359.1 - 0.0014 18.2 27.1 0.0021 17.6 27.1 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal KASH_CCD PF14662.6 EAX94359.1 - 0.0022 17.9 28.6 0.0034 17.2 28.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EAX94359.1 - 0.0046 15.9 30.2 0.013 14.4 11.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF812 PF05667.11 EAX94359.1 - 0.006 15.5 13.2 0.006 15.5 13.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) APG6_N PF17675.1 EAX94359.1 - 0.0068 16.9 24.1 0.18 12.4 23.5 2.3 1 1 1 2 2 2 2 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EAX94359.1 - 0.018 15.0 14.0 0.018 15.0 14.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 EAX94359.1 - 0.035 13.4 18.1 0.044 13.1 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EAX94359.1 - 0.057 13.5 29.2 2.9 8.0 29.2 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EAX94359.1 - 0.065 13.7 23.4 0.12 12.8 23.4 1.5 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 EAX94359.1 - 0.12 12.5 28.8 0.16 12.0 15.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 EAX94359.1 - 0.18 12.1 21.1 0.39 11.1 5.9 3.9 1 1 3 4 4 4 0 TSC-22/dip/bun family DUF2046 PF09755.9 EAX94359.1 - 0.45 9.7 26.5 1.1 8.5 26.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Geminin PF07412.12 EAX94359.1 - 0.64 9.7 25.5 0.47 10.2 6.1 3.4 1 1 3 4 4 4 0 Geminin TMF_TATA_bd PF12325.8 EAX94359.1 - 0.79 10.0 23.9 0.77 10.0 9.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding LRRFIP PF09738.9 EAX94359.1 - 0.82 9.1 25.6 1.3 8.4 12.0 2.1 1 1 1 2 2 2 0 LRRFIP family DUF4200 PF13863.6 EAX94359.1 - 1.1 9.7 31.2 4.6 7.7 13.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EAX94359.1 - 1.2 9.2 27.6 2.1 8.4 15.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C4H2 PF10146.9 EAX94359.1 - 2.1 8.6 19.2 3.8 7.8 19.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF724 PF05266.14 EAX94359.1 - 3.2 7.6 24.6 3.5 7.4 15.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 EAX94359.1 - 3.6 8.0 12.5 0.49 10.8 0.8 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Acylphosphatase PF00708.18 EAX94359.1 - 3.9 8.0 9.0 0.65 10.4 1.4 2.7 3 0 0 3 3 3 0 Acylphosphatase YabA PF06156.13 EAX94359.1 - 4.4 8.0 21.5 4.2 8.0 10.9 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 EAX94359.1 - 5.5 6.0 29.8 0.48 9.4 10.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 EAX94359.1 - 6.9 6.8 31.7 0.24 11.5 14.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Csm1_N PF18504.1 EAX94359.1 - 7.1 7.1 28.3 8.9 6.7 8.0 3.7 1 1 3 4 4 4 0 Csm1 N-terminal domain DUF745 PF05335.13 EAX94359.1 - 8.9 6.0 18.7 0.77 9.5 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 EAX94359.1 - 9.5 7.2 21.9 4.2 8.3 14.5 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Ank_2 PF12796.7 EAX94360.1 - 1.2e-66 221.3 5.6 1.8e-21 76.5 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94360.1 - 9.6e-48 160.0 0.0 2.1e-11 44.1 0.0 6.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX94360.1 - 3.3e-45 150.6 0.0 1.8e-06 28.1 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX94360.1 - 4e-42 141.7 0.0 1e-07 32.1 0.0 7.8 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94360.1 - 3.1e-35 116.2 0.0 5.1e-05 23.4 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Atg14 PF10186.9 EAX94360.1 - 0.0011 18.2 17.2 0.0015 17.7 17.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Epimerase PF01370.21 EAX94360.1 - 0.068 12.6 1.8 0.12 11.8 0.0 2.2 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family KASH_CCD PF14662.6 EAX94360.1 - 0.07 13.0 29.4 0.13 12.1 29.0 1.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EAX94360.1 - 0.071 13.1 26.0 0.21 11.6 26.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.6 EAX94360.1 - 0.11 12.0 26.0 0.88 9.0 11.1 2.3 1 1 1 2 2 2 0 Leucine zipper CALCOCO1 PF07888.11 EAX94360.1 - 0.13 11.1 20.1 0.18 10.6 20.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tweety PF04906.13 EAX94360.1 - 0.37 9.4 8.0 0.63 8.6 8.0 1.3 1 0 0 1 1 1 0 Tweety UPF0242 PF06785.11 EAX94360.1 - 0.72 9.9 33.2 0.27 11.3 15.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 EAX94360.1 - 0.87 9.7 28.9 1.5 8.9 2.7 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase YfmQ PF10787.9 EAX94360.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.2 3 2 2 5 5 5 0 Uncharacterised protein from bacillus cereus group Cep57_CLD_2 PF14197.6 EAX94360.1 - 1.8 8.7 24.8 0.061 13.4 12.7 2.9 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 EAX94360.1 - 1.8 9.1 32.0 1.3 9.6 11.2 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 EAX94360.1 - 2.2 7.1 27.1 0.92 8.3 12.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EAX94360.1 - 2.7 7.8 21.8 0.25 11.1 12.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4164 PF13747.6 EAX94360.1 - 3.8 7.9 16.4 0.85 9.9 4.7 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 EAX94360.1 - 4.1 7.9 24.0 2.6 8.6 21.8 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EAX94360.1 - 5.3 7.3 23.5 1.6 9.0 8.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAX94360.1 - 7.4 5.8 14.5 12 5.1 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol_B_2 PF03175.13 EAX94362.1 - 2.9e-24 85.8 10.9 1.4e-23 83.6 10.9 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX94363.1 - 0.019 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX94364.1 - 0.018 15.4 0.6 0.032 14.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94364.1 - 2.8 7.9 5.8 3 7.9 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX94365.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX94366.1 - 0.031 14.3 8.1 0.048 13.7 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX94366.1 - 1.2 9.6 5.3 1.7 9.1 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX94367.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX94367.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain B2-adapt-app_C PF09066.10 EAX94370.1 - 0.16 12.1 1.8 4 7.6 0.1 3.6 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain Trypan_PARP PF05887.11 EAX94370.1 - 1.1 9.2 9.9 2 8.4 9.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DHC_N2 PF08393.13 EAX94371.1 - 7.2e-42 143.9 5.1 7.2e-42 143.9 5.1 6.8 5 3 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 Atg14 PF10186.9 EAX94371.1 - 0.00023 20.3 6.0 0.00023 20.3 6.0 3.5 4 0 0 4 4 4 1 Vacuolar sorting 38 and autophagy-related subunit 14 KilA-N PF04383.13 EAX94371.1 - 6.1 6.7 12.4 2.3 8.1 0.1 4.9 4 0 0 4 4 4 0 KilA-N domain Memo PF01875.17 EAX94372.1 - 1.3e-59 201.5 0.1 1.6e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein Peptidase_C13 PF01650.18 EAX94373.1 - 2.4e-57 194.4 0.2 3.4e-57 193.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family EF-hand_7 PF13499.6 EAX94374.1 - 3.3e-13 49.9 0.0 1.1e-05 25.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX94374.1 - 7.7e-13 47.3 3.5 4.4e-06 26.2 0.0 4.9 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 EAX94374.1 - 8.5e-13 46.9 0.4 9.8e-05 21.6 0.0 5.1 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 EAX94374.1 - 6.1e-06 26.0 2.0 6 6.8 0.0 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX94374.1 - 2.7e-05 23.4 2.6 0.33 10.5 0.0 4.0 5 0 0 5 5 5 2 EF hand Caleosin PF05042.13 EAX94374.1 - 0.0042 17.0 0.0 0.014 15.4 0.0 1.8 1 1 1 2 2 2 1 Caleosin related protein C6_DPF PF10170.9 EAX94376.1 - 0.084 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich domain RhoGEF PF00621.20 EAX94377.1 - 5.8e-24 85.3 2.0 8e-24 84.9 1.1 1.7 2 0 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 EAX94377.1 - 6.1e-19 67.8 5.0 3.9e-05 23.6 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX94377.1 - 2.4e-17 62.5 12.7 0.012 15.8 0.0 7.1 4 1 3 7 7 7 5 Kelch motif Kelch_5 PF13854.6 EAX94377.1 - 8.3e-16 57.6 2.6 8.1e-05 22.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EAX94377.1 - 7e-13 47.9 3.0 0.0038 16.8 0.0 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAX94377.1 - 2.9e-12 46.0 8.1 0.096 12.7 0.0 6.2 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 EAX94377.1 - 4.9e-08 33.1 4.0 0.79 10.1 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain LRR_9 PF14580.6 EAX94377.1 - 0.052 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat YccF PF03733.13 EAX94378.1 - 8.1e-14 52.1 16.2 8.1e-14 52.1 16.2 2.5 2 1 0 2 2 2 2 Inner membrane component domain Na_Ca_ex PF01699.24 EAX94379.1 - 5e-07 29.8 15.1 5e-07 29.8 15.1 2.8 2 1 0 2 2 2 1 Sodium/calcium exchanger protein SUR7 PF06687.12 EAX94379.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 SUR7/PalI family DNA_RNApol_7kD PF03604.13 EAX94379.1 - 0.37 10.5 2.9 0.65 9.7 2.9 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Symplekin_C PF12295.8 EAX94384.1 - 0.46 10.6 5.3 2.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Ank_5 PF13857.6 EAX94385.1 - 6.9e-25 86.8 3.0 1.1e-06 28.8 0.0 4.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX94385.1 - 3.4e-21 75.3 0.0 2.7e-09 37.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94385.1 - 8e-21 74.4 0.0 1e-09 38.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94385.1 - 2.4e-19 68.8 0.1 1.6e-06 28.3 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX94385.1 - 5.5e-18 63.2 0.1 0.0016 18.8 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Na_trans_assoc PF06512.13 EAX94385.1 - 8.9e-05 22.9 0.3 8.9e-05 22.9 0.3 2.1 2 1 0 2 2 2 1 Sodium ion transport-associated OmpH PF03938.14 EAX94385.1 - 0.0047 17.3 21.9 0.0047 17.3 21.9 4.1 2 1 2 4 4 4 1 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 EAX94385.1 - 0.076 10.9 16.1 0.1 10.5 16.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FCD PF07729.12 EAX94385.1 - 0.74 10.3 8.3 12 6.3 2.5 3.8 3 1 0 3 3 3 0 FCD domain CotJB PF12652.7 EAX94385.1 - 1.7 8.9 5.7 1.4 9.2 3.3 2.2 1 1 1 2 2 2 0 CotJB protein HMG_box PF00505.19 EAX94386.1 - 1.7e-15 57.1 0.7 3.2e-15 56.3 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX94386.1 - 1.4e-10 41.7 0.3 3.2e-10 40.4 0.2 1.6 2 0 0 2 2 2 1 HMG-box domain DUF1542 PF07564.11 EAX94386.1 - 0.0047 17.0 6.0 0.0075 16.4 5.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) UvrD_C PF13361.6 EAX94386.1 - 0.0085 15.5 1.5 0.0098 15.3 1.5 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4355 PF14265.6 EAX94386.1 - 0.015 15.6 5.8 0.02 15.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3106 PF11304.8 EAX94386.1 - 0.042 14.3 1.0 0.062 13.8 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF2458 PF10454.9 EAX94387.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) F5_F8_type_C PF00754.25 EAX94388.1 - 6.3e-13 49.0 0.4 1.4e-06 28.4 0.2 2.5 2 0 0 2 2 2 2 F5/8 type C domain T_Ag_DNA_bind PF02217.16 EAX94388.1 - 0.37 11.4 2.3 41 4.9 0.1 3.2 3 0 0 3 3 3 0 Origin of replication binding protein VHS PF00790.19 EAX94389.1 - 0.21 11.4 4.8 0.78 9.6 0.0 3.3 3 1 1 4 4 4 0 VHS domain RhoGEF PF00621.20 EAX94390.1 - 7e-40 137.2 4.4 7e-40 137.2 4.4 2.4 3 0 0 3 3 3 1 RhoGEF domain Kelch_6 PF13964.6 EAX94390.1 - 7.9e-16 57.7 2.2 1.2e-05 25.4 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 EAX94390.1 - 6.4e-15 54.9 5.7 1.6e-08 34.4 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX94390.1 - 9.3e-13 47.5 0.0 6.8e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 EAX94390.1 - 3.2e-12 46.1 1.0 4.6e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EAX94390.1 - 3.1e-10 40.1 0.4 3.4e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EAX94390.1 - 1.4e-06 28.1 0.6 0.00015 21.6 0.0 3.3 3 0 0 3 3 3 1 Kelch motif DUF4366 PF14283.6 EAX94390.1 - 6.6 6.8 7.9 64 3.6 7.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Ntox35 PF15534.6 EAX94391.1 - 0.0044 17.4 9.6 1.2e+02 3.2 0.1 6.7 7 0 0 7 7 7 0 Bacterial toxin 35 HCBP_related PF06594.11 EAX94391.1 - 0.0057 16.6 0.1 8.2 6.5 0.0 3.2 2 0 0 2 2 2 2 Haemolysin-type calcium binding protein related domain DUF5449 PF17528.2 EAX94391.1 - 0.029 14.2 10.5 65 3.2 0.2 5.6 5 0 0 5 5 5 0 Family of unknown function (DUF5449) Integrase_Zn PF02022.19 EAX94392.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain TMEM171 PF15471.6 EAX94392.1 - 0.53 9.2 2.4 0.85 8.5 2.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 WD40_like PF17005.5 EAX94395.1 - 0.00031 20.2 3.1 0.0017 17.7 3.0 2.1 1 1 0 1 1 1 1 WD40-like domain DUF16 PF01519.16 EAX94395.1 - 0.28 11.7 2.4 0.64 10.5 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Mitochondr_Som1 PF11093.8 EAX94398.1 - 0.019 15.0 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial export protein Som1 EST1 PF10374.9 EAX94398.1 - 0.069 13.8 1.1 0.11 13.2 1.1 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 DUF2262 PF10020.9 EAX94398.1 - 0.19 12.1 6.8 0.23 11.8 6.8 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) cobW PF02492.19 EAX94398.1 - 1.4 8.5 4.2 3 7.4 0.6 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lipoprotein_Ltp PF07553.11 EAX94398.1 - 1.8 8.9 5.6 0.67 10.3 0.7 2.3 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Ribosomal_L5_C PF00673.21 EAX94399.1 - 3.5e-17 62.3 0.0 5.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAX94399.1 - 1e-09 38.5 0.3 1.7e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Gryzun-like PF12742.7 EAX94400.1 - 0.022 14.7 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking LRR_5 PF13306.6 EAX94401.1 - 2.8e-59 198.6 53.7 1.5e-26 92.8 6.1 3.9 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94401.1 - 0.00067 19.4 2.3 1.5 8.6 0.5 4.1 3 1 1 4 4 4 2 Leucine rich repeat FNIP PF05725.12 EAX94401.1 - 5.4 7.3 13.2 1.6 9.0 1.4 5.0 3 2 0 3 3 3 0 FNIP Repeat LRR_5 PF13306.6 EAX94402.1 - 9.3e-97 319.8 34.7 1.7e-29 102.4 2.3 5.0 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX94403.1 - 2.6e-24 85.6 5.5 3.1e-24 85.4 5.5 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX94404.1 - 1e-155 510.5 107.9 3.6e-26 91.6 7.7 7.4 1 1 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94404.1 - 1.1e-07 31.5 13.7 0.002 17.9 0.0 8.6 7 2 3 10 10 10 3 Leucine rich repeat Pentapeptide_4 PF13599.6 EAX94404.1 - 0.0017 18.5 15.2 2.7 8.2 4.2 7.1 6 2 1 7 7 7 1 Pentapeptide repeats (9 copies) A2M PF00207.22 EAX94404.1 - 0.11 12.4 0.0 23 4.9 0.0 3.7 3 1 1 4 4 4 0 Alpha-2-macroglobulin family Ank_4 PF13637.6 EAX94405.1 - 2.6e-10 40.6 0.1 8e-06 26.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94405.1 - 3.5e-07 30.7 0.4 0.00046 20.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94405.1 - 1.5e-05 25.0 0.3 0.063 13.9 0.0 4.1 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX94405.1 - 0.022 15.1 1.6 0.091 13.1 0.0 2.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 EAX94405.1 - 0.1 13.1 0.5 0.76 10.3 0.1 2.5 2 1 0 2 2 2 0 Ankyrin repeat Chlam_PMP PF02415.17 EAX94406.1 - 0.14 12.7 0.2 0.14 12.7 0.2 8.0 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF3839 PF12943.7 EAX94407.1 - 9.8e-112 372.3 8.2 1.1e-111 372.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX94407.1 - 0.22 12.0 1.4 0.36 11.3 0.5 2.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX94409.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX94410.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX94410.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase DUF3991 PF13154.6 EAX94412.1 - 0.018 15.4 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) tRNA_anti-codon PF01336.25 EAX94412.1 - 0.38 10.8 3.2 1.4 8.9 0.0 3.4 5 0 0 5 5 5 0 OB-fold nucleic acid binding domain GAS PF13851.6 EAX94414.1 - 0.0032 16.8 17.3 0.011 15.1 4.0 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding MCC-bdg_PDZ PF10506.9 EAX94414.1 - 0.045 13.8 0.1 0.045 13.8 0.1 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome eIF3_N PF09440.10 EAX94414.1 - 0.59 10.6 8.7 2 8.9 1.3 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Cob_adeno_trans PF01923.18 EAX94414.1 - 0.73 10.0 8.0 1.1 9.4 1.4 2.7 1 1 0 2 2 2 0 Cobalamin adenosyltransferase TPD52 PF04201.15 EAX94414.1 - 1.5 8.4 10.1 0.26 10.9 2.7 2.5 2 1 1 3 3 3 0 Tumour protein D52 family DUF1664 PF07889.12 EAX94414.1 - 2.2 8.3 9.0 1.2 9.2 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Metal_resist PF13801.6 EAX94414.1 - 2.6 8.3 9.5 1.4 9.1 6.9 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Big_3_3 PF13750.6 EAX94415.1 - 6.5e-05 22.6 7.6 1.4 8.5 2.7 4.6 4 1 0 4 4 4 3 Bacterial Ig-like domain (group 3) Cadherin-like PF12733.7 EAX94415.1 - 0.034 14.7 4.4 3.7 8.2 0.1 3.8 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain DUF4832 PF16116.5 EAX94415.1 - 0.04 13.8 0.2 5.8 6.7 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4832) DUF4625 PF15418.6 EAX94415.1 - 0.11 12.8 16.2 8 6.7 0.0 5.6 4 2 1 5 5 5 0 Domain of unknown function (DUF4625) DUF3839 PF12943.7 EAX94416.1 - 9.6e-141 467.3 8.9 1.2e-140 466.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX94416.1 - 0.098 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX94416.1 - 0.1 13.0 0.9 0.86 10.1 0.2 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spo12 PF05032.12 EAX94417.1 - 6.6 6.7 12.9 0.21 11.5 2.9 3.0 3 0 0 3 3 3 0 Spo12 family ASH PF15780.5 EAX94421.1 - 2.2e-41 140.0 67.2 0.0019 18.3 0.5 20.7 20 2 0 21 21 20 13 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EAX94421.1 - 2.7e-25 88.5 2.3 0.004 17.3 0.0 11.4 13 0 0 13 13 12 6 Flagellar-associated PapD-like DUF1573 PF07610.11 EAX94421.1 - 5.9e-18 64.7 52.1 0.016 15.3 0.2 16.9 18 0 0 18 18 18 6 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 EAX94421.1 - 1.1e-13 51.0 50.4 0.00018 21.3 3.5 15.8 17 1 0 17 17 17 5 MSP (Major sperm protein) domain MYCBPAP PF14646.6 EAX94421.1 - 2.1e-11 43.4 3.8 1.2e-06 27.8 0.0 7.0 8 0 0 8 8 8 2 MYCBP-associated protein family AAA_18 PF13238.6 EAX94421.1 - 1.4e-05 25.7 0.0 3.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EAX94421.1 - 0.0012 19.1 0.0 0.0012 19.1 0.0 4.2 4 0 0 4 4 4 1 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 EAX94421.1 - 0.01 16.1 0.0 0.039 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EAX94421.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 EAX94421.1 - 0.058 13.5 0.0 0.058 13.5 0.0 2.3 2 0 0 2 2 1 0 Shikimate kinase Phage_TAC_10 PF10963.8 EAX94421.1 - 0.097 12.9 0.7 3.9 7.7 0.0 3.7 3 0 0 3 3 3 0 Phage tail assembly chaperone TMEM131_like PF12371.8 EAX94421.1 - 0.11 12.8 31.1 5.5 7.3 0.0 11.8 13 1 0 13 13 13 0 Transmembrane protein 131-like FixG_C PF11614.8 EAX94421.1 - 4.5 7.5 13.9 30 4.8 0.0 7.3 8 0 0 8 8 8 0 IG-like fold at C-terminal of FixG, putative oxidoreductase YlbD_coat PF14071.6 EAX94422.1 - 0.03 14.6 0.7 0.03 14.6 0.7 1.9 2 0 0 2 2 2 0 Putative coat protein DUF948 PF06103.11 EAX94422.1 - 0.11 12.7 3.1 0.2 11.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 EAX94422.1 - 0.19 12.0 7.7 0.63 10.3 7.7 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1542 PF07564.11 EAX94422.1 - 0.41 10.8 5.9 0.075 13.1 2.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) HR1 PF02185.16 EAX94422.1 - 1.5 9.0 5.5 1.2 9.3 0.2 2.8 3 0 0 3 3 3 0 Hr1 repeat DUF4094 PF13334.6 EAX94422.1 - 1.5 9.3 5.1 4.6 7.7 1.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 EAX94422.1 - 2 8.8 8.9 3.5 8.0 0.2 3.8 3 1 1 4 4 4 0 TSC-22/dip/bun family Allexi_40kDa PF05549.11 EAX94422.1 - 8.6 5.8 11.7 0.61 9.5 3.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein PSP PF04046.16 EAX94423.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94424.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat K1 PF02960.14 EAX94427.1 - 0.38 10.9 2.7 0.89 9.7 0.3 2.6 1 1 0 2 2 2 0 K1 glycoprotein Pkinase PF00069.25 EAX94428.1 - 1.8e-53 181.6 0.1 2.3e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94428.1 - 3.1e-36 125.0 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94428.1 - 7.4e-05 22.2 0.0 0.00054 19.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Myb_DNA-binding PF00249.31 EAX94429.1 - 2e-20 72.7 6.4 2e-10 40.7 1.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94429.1 - 2.3e-14 53.4 5.5 1.6e-09 37.8 1.8 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX94429.1 - 3.4e-06 27.3 4.1 0.00066 19.9 1.6 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EAX94429.1 - 0.00031 20.8 0.9 0.41 10.7 0.1 2.6 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 EAX94429.1 - 0.047 13.8 3.6 4.3 7.5 0.8 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EAX94429.1 - 0.054 13.4 0.7 0.091 12.7 0.1 1.7 1 1 0 1 1 1 0 Myb DNA-binding like SUI1 PF01253.22 EAX94431.1 - 6.2e-19 68.3 1.9 1.2e-18 67.4 1.9 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 CCDC53 PF10152.9 EAX94431.1 - 0.37 11.2 2.9 4.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ank_2 PF12796.7 EAX94432.1 - 2e-20 73.2 0.2 3.8e-07 30.6 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX94432.1 - 7.3e-18 64.3 3.1 7.3e-18 64.3 3.1 4.7 5 2 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX94432.1 - 3.4e-14 53.0 0.8 1.6e-05 25.3 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX94432.1 - 1.6e-13 50.4 0.3 0.0011 19.3 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAX94432.1 - 4.9e-13 48.0 0.6 0.0067 16.8 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX94432.1 - 1.9e-10 40.8 0.9 1e-06 28.9 0.0 5.2 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF1815 PF08844.10 EAX94432.1 - 0.18 11.8 0.3 30 4.7 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1815) Metallophos PF00149.28 EAX94433.1 - 9.5e-36 124.2 0.1 1.2e-35 123.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX94433.1 - 1.3e-10 41.6 0.4 2.4e-10 40.7 0.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain IFT20 PF14931.6 EAX94434.1 - 0.015 15.4 12.9 0.015 15.4 12.9 3.9 2 1 2 4 4 4 0 Intraflagellar transport complex B, subunit 20 BLOC1_2 PF10046.9 EAX94434.1 - 0.023 15.0 5.6 0.023 15.0 5.6 5.1 2 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 EAX94434.1 - 0.026 14.6 4.1 0.026 14.6 4.1 5.2 3 1 2 5 5 5 0 bZIP transcription factor bZIP_2 PF07716.15 EAX94434.1 - 0.028 14.5 4.2 0.028 14.5 4.2 4.7 4 1 1 6 6 6 0 Basic region leucine zipper DivIC PF04977.15 EAX94434.1 - 0.16 11.7 40.2 0.06 13.1 3.3 5.2 3 1 1 5 5 5 0 Septum formation initiator DUF5601 PF18151.1 EAX94434.1 - 0.21 11.9 10.5 0.11 12.8 5.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) DUF1515 PF07439.11 EAX94434.1 - 0.58 10.2 7.4 31 4.6 6.6 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Cnn_1N PF07989.11 EAX94434.1 - 1.8 8.8 37.9 0.061 13.5 11.2 4.3 3 1 2 5 5 5 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EAX94434.1 - 3.5 7.7 45.8 2.7 8.0 10.0 4.4 3 1 2 5 5 5 0 TPR/MLP1/MLP2-like protein RFX_DNA_binding PF02257.15 EAX94435.1 - 0.0002 21.9 0.2 0.0003 21.4 0.2 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX94435.1 - 0.00077 19.9 1.7 0.0013 19.2 1.7 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX94435.1 - 0.044 13.8 0.9 0.09 12.8 0.1 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DDR PF08841.10 EAX94436.1 - 0.08 11.9 0.1 0.075 12.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX94436.1 - 0.089 13.2 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX94437.1 - 0.11 12.5 9.6 0.15 12.0 9.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RFX_DNA_binding PF02257.15 EAX94438.1 - 9.7e-05 22.9 0.2 0.00015 22.3 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAX94438.1 - 0.00025 21.5 2.3 0.00038 20.9 2.3 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAX94438.1 - 0.044 13.8 0.7 0.078 13.0 0.1 1.7 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain KilA-N PF04383.13 EAX94439.1 - 3.5e-41 139.6 0.6 8.8e-41 138.3 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX94439.1 - 0.24 11.4 2.9 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein T5orf172 PF10544.9 EAX94440.1 - 7.8e-07 29.6 0.2 2.2e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX94440.1 - 0.018 14.6 1.2 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX94440.1 - 0.023 14.5 1.9 0.074 12.9 0.5 2.4 2 2 0 2 2 2 0 KilA-N domain DUF1731 PF08338.11 EAX94441.1 - 0.11 12.3 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX94443.1 - 3.9e-72 241.7 3.6 5.1e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pro-NT_NN PF07421.11 EAX94444.1 - 0.01 16.1 1.0 0.01 16.1 1.0 1.0 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor MAJIN PF15077.6 EAX94444.1 - 4 7.2 8.9 4.1 7.1 8.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Laminin_I PF06008.14 EAX94445.1 - 6e-29 101.5 66.2 0.00082 19.1 2.7 9.8 1 1 8 9 9 9 9 Laminin Domain I KASH_CCD PF14662.6 EAX94445.1 - 6e-17 62.1 52.4 0.00028 20.8 9.8 5.8 1 1 6 7 7 7 7 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAX94445.1 - 4.2e-16 59.0 22.2 0.41 10.0 0.7 11.1 1 1 11 12 12 12 6 Domain of unknown function (DUF3552) DUF2935 PF11155.8 EAX94445.1 - 1.1e-12 48.3 0.4 1.3 9.4 0.0 8.6 1 1 1 2 2 2 2 Domain of unknown function (DUF2935) ERM PF00769.19 EAX94445.1 - 2.5e-12 47.1 28.3 0.071 12.9 5.6 7.0 1 1 5 6 6 6 6 Ezrin/radixin/moesin family Spc7 PF08317.11 EAX94445.1 - 9.6e-11 41.1 53.2 0.002 17.0 2.8 7.7 1 1 6 7 7 7 6 Spc7 kinetochore protein Laminin_II PF06009.12 EAX94445.1 - 2e-10 40.8 63.7 0.17 11.9 4.8 9.1 1 1 9 10 10 10 8 Laminin Domain II BLOC1_2 PF10046.9 EAX94445.1 - 2.2e-08 34.3 48.3 1.4 9.3 1.8 12.1 1 1 7 8 8 8 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EAX94445.1 - 1.6e-07 30.9 102.5 0.017 14.5 13.4 8.1 1 1 7 8 8 8 8 Protein of unknown function (DUF3450) GCN5L1 PF06320.13 EAX94445.1 - 2.8e-07 30.7 31.7 2.5 8.3 0.4 10.9 1 1 12 13 13 13 1 GCN5-like protein 1 (GCN5L1) BRE1 PF08647.11 EAX94445.1 - 7.4e-06 26.0 52.3 0.55 10.3 5.9 8.9 1 1 8 10 10 10 6 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EAX94445.1 - 7.5e-06 26.0 34.6 1.6 8.8 0.9 8.5 1 1 8 9 9 9 3 Protein of unknown function (DUF1664) Sec34 PF04136.15 EAX94445.1 - 2.5e-05 24.2 94.0 0.56 10.1 1.0 12.3 1 1 14 15 15 15 5 Sec34-like family DUF4200 PF13863.6 EAX94445.1 - 6.5e-05 23.3 0.3 2.7 8.4 0.0 5.0 2 2 4 6 6 6 1 Domain of unknown function (DUF4200) CheZ PF04344.13 EAX94445.1 - 0.00041 20.3 42.4 0.31 10.9 1.9 6.9 1 1 5 7 7 7 4 Chemotaxis phosphatase, CheZ CENP-F_leu_zip PF10473.9 EAX94445.1 - 0.00043 20.3 38.0 0.49 10.4 1.1 6.8 1 1 7 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EAX94445.1 - 0.00071 19.6 102.1 0.24 11.5 14.6 8.4 1 1 9 10 10 10 4 TPR/MLP1/MLP2-like protein YabA PF06156.13 EAX94445.1 - 0.0008 20.0 22.9 50 4.6 1.6 9.0 1 1 1 2 2 1 0 Initiation control protein YabA UPF0449 PF15136.6 EAX94445.1 - 0.0023 18.3 57.3 18 5.9 1.5 11.5 1 1 9 10 10 10 0 Uncharacterised protein family UPF0449 Tropomyosin_1 PF12718.7 EAX94445.1 - 0.0032 17.6 33.5 4.6 7.4 2.4 8.0 1 1 8 9 9 9 2 Tropomyosin like Jnk-SapK_ap_N PF09744.9 EAX94445.1 - 0.045 14.0 64.6 3.3 7.9 2.1 9.3 1 1 8 9 9 9 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 EAX94445.1 - 0.057 13.9 36.0 8.8 6.9 0.1 10.4 2 2 4 7 7 7 0 Cell division protein ZapB DUF4686 PF15742.5 EAX94445.1 - 0.21 10.7 63.0 1 8.4 3.9 6.8 1 1 7 8 8 8 0 Domain of unknown function (DUF4686) V-ATPase_H_N PF03224.14 EAX94446.1 - 0.044 13.1 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Pox_A32 PF04665.12 EAX94447.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX94447.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX94447.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX94447.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX94447.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX94447.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX94447.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX94448.1 - 1.7e-155 515.6 14.2 2.1e-155 515.2 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX94448.1 - 0.25 11.2 1.7 0.76 9.6 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX94448.1 - 0.57 10.5 3.6 0.99 9.8 0.5 2.7 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX94448.1 - 0.94 10.0 8.0 2.6 8.6 1.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX94449.1 - 0.068 13.6 0.5 0.15 12.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Guanylate_cyc PF00211.20 EAX94450.1 - 6.8e-42 143.2 0.0 3e-41 141.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX94450.1 - 1.2e-11 44.8 0.4 4.4e-11 43.0 0.4 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX94450.1 - 1.6e-06 28.1 0.1 4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX94450.1 - 0.003 17.0 0.1 0.003 17.0 0.1 2.3 3 0 0 3 3 3 1 Heme NO binding associated DegQ PF08181.11 EAX94450.1 - 0.033 14.3 1.0 0.1 12.7 0.3 2.2 2 0 0 2 2 2 0 DegQ (SacQ) family Shisa PF13908.6 EAX94450.1 - 0.11 12.7 0.8 2.3 8.4 0.2 2.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF5383 PF17355.2 EAX94450.1 - 0.48 10.8 12.3 0.25 11.7 2.3 4.3 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Ank_4 PF13637.6 EAX94451.1 - 5.1e-20 71.6 0.7 2.2e-08 34.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94451.1 - 1.3e-16 61.0 1.2 7.3e-09 36.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94451.1 - 6.9e-16 57.9 2.0 0.0022 18.4 0.4 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX94451.1 - 1.1e-14 53.1 0.5 0.0022 18.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX94451.1 - 5.1e-14 52.2 0.5 4.5e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX94451.1 - 0.041 13.6 0.1 0.15 11.8 0.1 2.0 1 1 1 2 2 2 0 Shigella flexneri OspC protein ANAPC4_WD40 PF12894.7 EAX94453.1 - 7e-15 55.1 0.0 0.0093 16.2 0.0 6.0 5 2 2 7 7 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EAX94453.1 - 1.6e-09 37.4 26.0 0.00011 21.4 1.0 6.8 4 4 3 8 8 8 2 Coatomer WD associated region Clathrin PF00637.20 EAX94453.1 - 1.2e-08 34.9 29.0 0.014 15.3 0.1 9.6 7 2 3 10 10 10 3 Region in Clathrin and VPS WD40 PF00400.32 EAX94453.1 - 3.3e-05 24.6 0.7 1.6 9.7 0.1 4.6 3 0 0 3 3 3 1 WD domain, G-beta repeat TPR_14 PF13428.6 EAX94453.1 - 0.00025 21.6 15.5 23 6.1 0.0 10.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAX94453.1 - 0.0011 18.8 13.1 0.11 12.6 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX94453.1 - 0.0012 19.0 8.8 0.93 9.8 0.2 6.4 5 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 WD40_3 PF15911.5 EAX94453.1 - 0.0012 18.7 0.0 0.0053 16.7 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat PD40 PF07676.12 EAX94453.1 - 0.0016 18.3 2.6 0.23 11.5 0.3 2.9 3 0 0 3 3 2 1 WD40-like Beta Propeller Repeat TPR_6 PF13174.6 EAX94453.1 - 0.0069 17.0 15.4 0.55 11.0 0.1 7.8 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAX94453.1 - 0.021 14.6 30.4 0.095 12.6 0.3 10.2 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_21 PF09976.9 EAX94453.1 - 0.12 12.1 15.2 0.35 10.6 1.2 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 EAX94453.1 - 0.14 12.7 15.9 1.9 9.0 0.0 7.7 6 3 2 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX94453.1 - 0.39 11.0 34.9 0.37 11.0 0.3 10.9 12 1 1 13 13 12 0 Tetratricopeptide repeat zf-ACC PF17848.1 EAX94453.1 - 1.1 9.4 3.6 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TPR_8 PF13181.6 EAX94453.1 - 1.2 9.5 25.1 0.17 12.2 0.2 8.9 9 1 1 10 10 10 0 Tetratricopeptide repeat DZR PF12773.7 EAX94453.1 - 1.5 8.9 14.3 1.7 8.7 1.8 2.5 1 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 EAX94453.1 - 2 7.8 6.8 5.2 6.5 6.8 1.7 1 0 0 1 1 1 0 NMD3 family Utp13 PF08625.11 EAX94453.1 - 2.7 7.9 7.1 7.8 6.4 0.0 4.2 5 1 1 6 6 6 0 Utp13 specific WD40 associated domain PknG_rubred PF16919.5 EAX94453.1 - 4.2 7.5 9.3 14 5.8 9.3 1.8 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain HNOB PF07700.15 EAX94455.1 - 0.0097 15.9 0.2 0.034 14.1 0.1 2.0 2 0 0 2 2 2 1 Haem-NO-binding DUF5578 PF17741.1 EAX94455.1 - 0.1 12.0 2.2 0.57 9.6 0.6 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5578) DUF2009 PF09418.10 EAX94456.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Myb_DNA-binding PF00249.31 EAX94457.1 - 3e-27 94.5 1.0 7.4e-15 54.9 0.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94457.1 - 2.4e-21 75.7 5.5 9.7e-12 45.0 0.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX94457.1 - 3e-09 36.9 2.9 0.00059 19.8 0.0 3.1 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX94457.1 - 6.4e-09 35.6 5.0 1.1e-06 28.5 1.0 2.5 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX94457.1 - 0.0061 16.7 2.8 0.69 10.1 0.2 3.0 1 1 1 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX94457.1 - 0.03 14.7 4.9 0.049 14.0 2.0 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain THP2 PF09432.10 EAX94457.1 - 0.038 14.0 0.7 0.14 12.3 0.3 2.1 1 1 1 2 2 2 0 Tho complex subunit THP2 Glyco_transf_8C PF08437.10 EAX94457.1 - 0.038 14.1 1.5 0.36 11.0 0.1 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal SANT_DAMP1_like PF16282.5 EAX94457.1 - 0.054 13.7 1.1 0.12 12.5 1.1 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Sigma70_r4_2 PF08281.12 EAX94457.1 - 0.083 12.6 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3447 PF11929.8 EAX94458.1 - 2.8e-19 68.8 2.6 2.8e-19 68.8 2.6 3.4 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94458.1 - 9.5e-05 22.9 0.1 0.22 12.1 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Pih1_fungal_CS PF18482.1 EAX94458.1 - 0.0085 16.6 0.8 0.023 15.2 0.8 1.7 1 0 0 1 1 1 1 Fungal Pih1 CS domain Astacin PF01400.24 EAX94458.1 - 0.023 14.3 1.5 1.3 8.6 0.6 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) UBA PF00627.31 EAX94459.1 - 0.00033 20.5 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 EAX94459.1 - 0.01 15.6 0.2 0.034 13.9 0.2 1.9 1 0 0 1 1 1 0 Ubiquitin family Ras PF00071.22 EAX94460.1 - 1e-26 93.5 0.0 1.1e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94460.1 - 1.3e-24 86.7 0.0 1.5e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94460.1 - 2e-05 24.1 0.0 2.3e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX94460.1 - 9.8e-05 21.8 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX94460.1 - 0.00069 19.7 0.0 0.00082 19.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX94460.1 - 0.023 15.0 0.1 0.027 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX94460.1 - 0.025 15.0 0.0 0.031 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EAX94460.1 - 0.029 14.1 0.1 0.057 13.2 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX94460.1 - 0.032 13.5 0.0 0.041 13.2 0.0 1.3 1 1 0 1 1 1 0 Septin Sigma54_activat PF00158.26 EAX94460.1 - 0.059 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EAX94460.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EAX94460.1 - 0.07 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX94460.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EAX94460.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 EAX94461.1 - 0.15 11.0 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gly_rich PF12810.7 EAX94462.1 - 9.4e-20 71.6 25.3 1.2e-19 71.3 25.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly-zipper_Omp PF13488.6 EAX94463.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX94463.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94463.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX94464.1 - 3.8e-05 23.3 3.2 4.1e-05 23.2 2.5 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX94464.1 - 0.0069 16.4 2.3 0.0072 16.3 0.2 2.0 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX94464.1 - 0.0096 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX94464.1 - 0.05 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX94464.1 - 0.28 11.5 4.3 0.15 12.3 1.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) TPR_MLP1_2 PF07926.12 EAX94466.1 - 0.044 13.8 0.2 0.056 13.5 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX94466.1 - 0.093 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX94466.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Alph_Pro_TM PF09608.10 EAX94467.1 - 4.8e-05 23.3 0.8 0.99 9.2 0.0 4.9 4 1 1 5 5 5 2 Putative transmembrane protein (Alph_Pro_TM) DUF4625 PF15418.6 EAX94467.1 - 0.0019 18.5 15.4 0.29 11.4 0.0 7.5 9 0 0 9 9 9 2 Domain of unknown function (DUF4625) I-set PF07679.16 EAX94467.1 - 0.0031 17.6 2.4 8.4 6.5 0.0 5.7 5 0 0 5 5 5 1 Immunoglobulin I-set domain TMEM154 PF15102.6 EAX94467.1 - 0.012 15.5 1.5 0.049 13.5 1.5 2.1 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_M56 PF05569.11 EAX94467.1 - 0.038 13.2 0.1 0.073 12.2 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM51 PF15345.6 EAX94467.1 - 0.074 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 LRR19-TM PF15176.6 EAX94467.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4448 PF14610.6 EAX94467.1 - 0.21 11.3 4.6 0.14 11.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Big_7 PF17957.1 EAX94467.1 - 0.28 12.0 46.3 0.77 10.6 0.3 11.0 9 1 1 10 10 10 0 Bacterial Ig domain MG1 PF17790.1 EAX94467.1 - 1.6 9.2 5.3 4.7 7.7 1.5 3.6 3 0 0 3 3 3 0 Macroglobulin domain MG1 DUF4107 PF13389.6 EAX94469.1 - 5.1e-71 238.1 3.6 6.7e-71 237.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) YlbE PF14003.6 EAX94469.1 - 0.11 13.0 0.8 0.23 11.9 0.8 1.6 1 0 0 1 1 1 0 YlbE-like protein DUF1476 PF07345.11 EAX94469.1 - 0.13 12.7 0.7 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX94470.1 - 0.0036 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX94471.1 - 1.2e-135 450.6 9.7 1.9e-135 449.9 9.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAX94471.1 - 0.016 15.7 0.1 0.094 13.3 0.1 2.3 2 0 0 2 2 2 0 T5orf172 domain MitMem_reg PF13012.6 EAX94471.1 - 0.12 12.8 0.8 1.9 9.0 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function RUN PF02759.19 EAX94471.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RUN domain KELK PF15796.5 EAX94471.1 - 1.1 9.7 5.2 0.97 9.9 0.4 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX94472.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX94473.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Robl_LC7 PF03259.17 EAX94474.1 - 5.5e-07 29.3 0.0 7.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF4366 PF14283.6 EAX94475.1 - 0.13 12.3 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HCV_NS4a PF01006.20 EAX94475.1 - 0.78 9.5 3.1 1.4 8.7 3.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Myb_DNA-binding PF00249.31 EAX94476.1 - 3.5e-28 97.5 0.8 8.6e-15 54.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94476.1 - 6.6e-22 77.5 1.1 7.2e-11 42.2 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX94476.1 - 0.0023 17.9 0.4 1.6 8.8 0.0 2.9 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX94476.1 - 0.022 14.6 0.2 0.1 12.5 0.0 2.3 2 2 1 3 3 3 0 Myb DNA-binding like HD_3 PF13023.6 EAX94476.1 - 0.075 13.0 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 HD domain Ank_2 PF12796.7 EAX94477.1 - 1.2e-05 25.8 0.1 4.4e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94477.1 - 4.8e-05 23.6 0.2 0.35 11.2 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94477.1 - 0.00029 21.1 0.1 1.8 9.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX94477.1 - 0.0012 19.2 0.1 1.7 9.4 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Spc7 PF08317.11 EAX94477.1 - 0.0017 17.3 21.1 0.0017 17.3 21.1 17.6 1 1 16 18 18 18 10 Spc7 kinetochore protein Ank_4 PF13637.6 EAX94477.1 - 0.0026 18.3 0.2 1.6 9.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_MLP1_2 PF07926.12 EAX94477.1 - 0.0037 17.3 37.4 0.0037 17.3 37.4 24.2 2 2 19 23 23 23 5 TPR/MLP1/MLP2-like protein DASH_Dam1 PF08653.10 EAX94477.1 - 0.0053 16.5 0.6 0.0053 16.5 0.6 24.1 19 7 6 26 26 26 1 DASH complex subunit Dam1 HALZ PF02183.18 EAX94477.1 - 0.008 16.4 3.7 0.008 16.4 3.7 28.6 22 7 11 33 33 33 4 Homeobox associated leucine zipper DUF5082 PF16888.5 EAX94478.1 - 0.00046 20.4 29.3 0.00046 20.4 29.3 19.5 1 1 16 19 19 19 6 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 EAX94478.1 - 0.0058 16.7 2.7 0.0058 16.7 2.7 26.2 5 4 19 25 25 25 5 TolA binding protein trimerisation DUF563 PF04577.14 EAX94479.1 - 1.1e-36 126.9 1.4 1.8e-36 126.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) PSP PF04046.16 EAX94480.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94481.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat BRO1 PF03097.18 EAX94482.1 - 0.13 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Phage_fiber PF03335.13 EAX94482.1 - 0.16 12.2 4.8 1.8 8.9 0.3 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat YmaF PF12788.7 EAX94482.1 - 0.21 12.1 1.8 3.6 8.2 1.9 2.3 1 1 1 2 2 2 0 YmaF family Pox_A32 PF04665.12 EAX94483.1 - 7.5e-07 28.8 2.9 7.5e-07 28.8 2.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX94483.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX94483.1 - 6.2e-05 22.8 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX94483.1 - 0.0001 22.3 3.0 0.00023 21.2 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX94483.1 - 0.00061 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX94483.1 - 0.0013 18.6 0.7 0.0025 17.6 0.7 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX94483.1 - 0.0019 17.9 0.5 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX94483.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX94483.1 - 0.071 12.7 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX94483.1 - 0.086 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX94483.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX94483.1 - 0.22 11.8 4.8 3.3 8.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX94484.1 - 4.8e-63 211.3 7.2 5.4e-63 211.2 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mito_fiss_reg PF05308.11 EAX94485.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX94485.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LRR_5 PF13306.6 EAX94487.1 - 8.7e-100 329.6 86.0 1.6e-25 89.5 7.1 7.1 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94487.1 - 1.9e-22 78.7 2.2 0.00012 21.8 0.0 9.0 6 3 5 11 11 11 6 Leucine rich repeat LRR_4 PF12799.7 EAX94487.1 - 0.00075 19.8 12.3 25 5.5 0.0 9.0 4 3 5 9 9 9 1 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EAX94488.1 - 2e-20 73.1 6.5 3.6e-06 27.5 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94488.1 - 1.9e-16 60.2 6.4 7.6e-06 26.4 0.2 6.0 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94488.1 - 6e-12 44.7 13.0 0.31 11.7 0.0 9.8 10 1 1 11 11 11 3 Ankyrin repeat Ank PF00023.30 EAX94488.1 - 7.7e-06 26.1 2.7 12 6.5 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX94488.1 - 9.4e-06 25.5 3.0 9.4e-06 25.5 3.0 9.1 8 3 2 10 10 10 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX94488.1 - 1.5e-05 25.1 1.7 4.4 7.7 0.3 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) MCM6_C PF18263.1 EAX94488.1 - 0.076 13.3 0.4 14 6.0 0.1 3.3 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain HTH_ABP1_N PF18107.1 EAX94488.1 - 0.088 12.5 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain LRR_5 PF13306.6 EAX94489.1 - 2e-18 66.5 10.1 9.4e-11 41.8 4.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94489.1 - 1.3e-11 44.1 3.5 6.5e-06 25.8 0.2 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EAX94489.1 - 0.048 14.1 0.9 0.3 11.6 0.1 2.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94490.1 - 2.1e-144 473.9 114.1 7.9e-28 97.0 2.1 6.1 1 1 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94490.1 - 1.1e-19 70.0 3.6 0.00049 19.8 0.0 8.8 6 2 6 12 12 12 7 Leucine rich repeat LRR_4 PF12799.7 EAX94490.1 - 0.0024 18.2 13.8 67 4.1 0.0 9.0 5 3 4 9 9 9 0 Leucine Rich repeats (2 copies) DUF4372 PF14294.6 EAX94490.1 - 0.078 13.1 0.3 5.6 7.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4372) LRR_5 PF13306.6 EAX94491.1 - 1.3e-93 309.7 74.6 7.5e-27 93.8 2.4 5.2 2 1 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94491.1 - 7.5e-20 70.5 5.9 9.3e-05 22.1 0.0 9.0 7 1 3 10 10 10 5 Leucine rich repeat LRR_4 PF12799.7 EAX94491.1 - 0.0011 19.4 16.4 19 5.8 0.0 9.1 5 3 4 9 9 9 1 Leucine Rich repeats (2 copies) DUF4372 PF14294.6 EAX94491.1 - 0.044 13.9 0.2 3 8.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4372) LRR_8 PF13855.6 EAX94492.1 - 4.7e-12 45.5 2.2 2.3e-06 27.3 0.2 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 EAX94492.1 - 1e-09 38.4 6.7 1.6e-09 37.8 5.8 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EAX94492.1 - 0.045 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94493.1 - 5.1e-61 204.3 35.2 2.9e-26 91.9 6.0 3.3 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94493.1 - 1.9e-15 56.3 0.9 0.0006 19.5 0.0 6.4 3 2 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EAX94493.1 - 0.041 14.3 13.7 2.1 8.9 0.6 5.7 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX94493.1 - 3.1 8.7 4.9 15 6.6 0.7 3.6 2 1 0 2 2 2 0 Leucine Rich Repeat Pkinase PF00069.25 EAX94494.1 - 4.5e-57 193.4 0.0 5.6e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94494.1 - 1.1e-33 116.7 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94494.1 - 3.3e-05 23.4 0.0 0.00015 21.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX94494.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX94494.1 - 0.0004 20.0 0.2 0.00085 19.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 EAX94494.1 - 0.014 14.4 0.5 0.029 13.4 0.5 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EAX94494.1 - 0.037 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LCD1 PF09798.9 EAX94495.1 - 0.0028 16.3 0.5 0.0036 15.9 0.5 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein LacI PF00356.21 EAX94496.1 - 1.7 8.5 4.1 3.3 7.6 0.2 3.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HAP1_N PF04849.13 EAX94497.1 - 0.0017 17.6 11.7 0.0017 17.6 11.7 3.6 1 1 1 3 3 3 2 HAP1 N-terminal conserved region DUF4201 PF13870.6 EAX94497.1 - 0.0026 17.5 5.6 0.0026 17.5 5.6 4.4 1 1 3 4 4 4 1 Domain of unknown function (DUF4201) Atg14 PF10186.9 EAX94497.1 - 0.0027 16.9 18.0 0.0027 16.9 18.0 2.4 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 EAX94497.1 - 0.0075 15.2 58.1 0.028 13.3 8.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF812) Eryth_link_C PF16915.5 EAX94497.1 - 0.12 12.4 1.2 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus AAA_13 PF13166.6 EAX94497.1 - 0.19 10.3 47.0 0.025 13.3 30.2 2.5 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 EAX94497.1 - 0.2 10.5 58.4 1.4 7.7 26.0 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EAX94497.1 - 1.7 8.0 55.8 11 5.4 27.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Indigoidine_A PF04227.12 EAX94497.1 - 1.9 7.8 10.6 0.18 11.2 3.1 2.2 2 0 0 2 2 2 0 Indigoidine synthase A like protein FAM219A PF15260.6 EAX94498.1 - 0.043 14.2 0.1 0.043 14.2 0.1 3.1 3 0 0 3 3 3 0 Protein family FAM219A Lipase_3 PF01764.25 EAX94499.1 - 1.1e-15 57.7 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EAX94499.1 - 0.058 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.16 EAX94500.1 - 6.9e-27 94.3 8.8 8.6e-27 94.0 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4704 PF15787.5 EAX94500.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) MFS_1 PF07690.16 EAX94501.1 - 0.00082 18.4 5.1 0.00082 18.4 5.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAX94501.1 - 0.056 12.0 6.4 0.069 11.7 6.4 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF713 PF05218.14 EAX94502.1 - 0.098 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) KN17_SH3 PF18131.1 EAX94503.1 - 0.39 10.9 1.5 0.82 9.8 0.8 1.9 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain DUF1910 PF08928.10 EAX94504.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) DHR-2 PF06920.13 EAX94505.1 - 5.3e-12 45.2 1.3 1.3e-11 43.8 1.3 1.5 1 1 0 1 1 1 1 Dock homology region 2 DUF4795 PF16043.5 EAX94507.1 - 0.012 15.3 5.8 1.1 8.8 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) ESAG1 PF03238.13 EAX94507.1 - 0.036 13.5 3.6 0.33 10.3 0.5 2.9 1 1 2 3 3 3 0 ESAG protein GST_C PF00043.25 EAX94507.1 - 0.05 13.8 0.5 1.7 8.9 0.0 3.0 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain PH_3 PF14593.6 EAX94507.1 - 0.062 13.4 0.5 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 PH domain EpuA PF11772.8 EAX94507.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta GP3_package PF16677.5 EAX94507.1 - 1.1 9.4 4.2 23 5.2 4.2 2.8 1 1 0 1 1 1 0 DNA-packaging protein gp3 Apolipoprotein PF01442.18 EAX94508.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TPR_2 PF07719.17 EAX94509.1 - 1.8e-07 30.7 0.2 0.0044 17.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX94509.1 - 3.2e-07 30.0 5.0 0.029 14.6 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX94509.1 - 4.4e-06 26.3 2.6 0.00059 19.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX94509.1 - 9.4e-05 22.2 0.0 0.82 9.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX94509.1 - 0.0002 21.6 0.1 0.87 9.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 EAX94509.1 - 0.0014 18.6 1.0 0.0038 17.2 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX94509.1 - 0.002 17.4 0.0 1.1 8.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAX94509.1 - 0.0028 18.1 0.0 1.2 9.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAX94509.1 - 0.0032 18.1 0.0 3.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAX94509.1 - 0.049 14.3 0.2 3.6 8.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX94509.1 - 0.065 14.1 0.0 2.9 8.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAX94509.1 - 0.11 12.2 1.4 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 EAX94509.1 - 0.28 11.6 1.5 3.3 8.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX94511.1 - 4.3e-48 164.0 0.0 5.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94511.1 - 2.3e-22 79.5 0.0 3.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX94511.1 - 0.0027 17.7 0.0 0.41 10.5 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EAX94511.1 - 0.0044 16.7 0.2 1.2 8.8 0.1 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX94511.1 - 0.0081 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX94511.1 - 0.0096 15.3 0.0 0.053 12.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX94511.1 - 0.038 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX94511.1 - 0.16 11.6 0.8 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Elf1 PF05129.13 EAX94512.1 - 0.0024 17.9 1.4 2.1 8.4 0.3 3.0 2 1 0 2 2 2 2 Transcription elongation factor Elf1 like SWIB PF02201.18 EAX94512.1 - 0.43 10.5 5.4 0.14 12.1 0.1 3.0 2 0 0 2 2 2 0 SWIB/MDM2 domain UPF0302 PF08864.10 EAX94514.1 - 0.098 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 UPF0302 domain MGC-24 PF05283.11 EAX94515.1 - 0.0025 18.3 0.1 0.0044 17.5 0.1 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 EAX94515.1 - 0.0051 16.7 0.1 0.0089 15.9 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 EAX94515.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Orthoreo_P10 PF07204.11 EAX94515.1 - 0.026 14.5 0.3 0.061 13.3 0.3 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 EAX94515.1 - 0.15 12.9 1.2 0.36 11.8 1.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trypan_PARP PF05887.11 EAX94515.1 - 0.3 11.0 11.4 0.45 10.5 11.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Laminin_G_3 PF13385.6 EAX94516.1 - 2.9e-22 79.4 1.0 2.1e-15 57.2 0.1 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EAX94516.1 - 0.021 15.4 0.2 8.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain Lipin_N PF04571.14 EAX94516.1 - 0.062 13.3 0.4 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 lipin, N-terminal conserved region UCH PF00443.29 EAX94517.1 - 1.4e-28 100.1 9.9 1.4e-28 100.1 9.9 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX94517.1 - 6.4e-07 29.3 16.7 0.00074 19.2 0.3 3.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Helicase_C PF00271.31 EAX94517.1 - 0.04 14.3 0.1 0.18 12.2 0.1 2.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAX94518.1 - 0.0048 15.7 0.0 0.014 14.2 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain FYRC PF05965.14 EAX94518.1 - 0.031 14.5 0.0 0.098 12.8 0.0 1.9 1 0 0 1 1 1 0 F/Y rich C-terminus Elf1 PF05129.13 EAX94518.1 - 0.099 12.7 0.3 7 6.8 0.0 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Helicase_C PF00271.31 EAX94518.1 - 0.34 11.3 3.9 0.19 12.1 0.1 2.6 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Roc PF08477.13 EAX94518.1 - 0.51 10.6 2.5 3.8 7.7 0.1 3.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EAX94519.1 - 8e-54 182.8 0.0 9.4e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94519.1 - 4.9e-27 94.8 0.0 6.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94519.1 - 8.6e-07 28.5 0.0 5.5e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX94519.1 - 0.0041 16.1 0.4 0.0064 15.5 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX94519.1 - 0.0041 16.5 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX94519.1 - 0.012 14.5 0.1 0.068 11.9 0.0 1.8 1 1 0 2 2 2 0 Fungal protein kinase HlyIII PF03006.20 EAX94520.1 - 2.8e-18 66.5 18.4 1.2e-17 64.4 18.4 1.8 1 1 0 1 1 1 1 Haemolysin-III related YitT_membrane PF02588.15 EAX94520.1 - 0.84 8.9 12.1 0.39 10.0 3.6 2.2 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 CD20 PF04103.15 EAX94520.1 - 1.2 9.2 8.5 0.41 10.7 2.4 2.4 2 0 0 2 2 2 0 CD20-like family NIF PF03031.18 EAX94521.1 - 4e-42 143.6 0.1 5e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CUB_2 PF02408.20 EAX94521.1 - 0.13 12.0 0.4 3.2 7.5 0.1 2.2 2 0 0 2 2 2 0 CUB-like domain Ank_2 PF12796.7 EAX94523.1 - 0.015 15.9 0.0 0.048 14.3 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) RPN7 PF10602.9 EAX94523.1 - 0.037 13.7 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Ank_4 PF13637.6 EAX94523.1 - 0.062 13.9 0.0 0.91 10.2 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF3781 PF12636.7 EAX94524.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4108 PF13390.6 EAX94525.1 - 8.8e-63 210.5 6.1 9.8e-63 210.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX94526.1 - 5.1e-05 23.7 2.5 0.00036 21.0 2.5 2.3 1 1 0 1 1 1 1 Poxvirus D5 protein-like CHIPS PF11434.8 EAX94527.1 - 0.062 13.1 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS DAGK_cat PF00781.24 EAX94529.1 - 3.5e-28 97.7 0.0 4.8e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Fe-ADH_2 PF13685.6 EAX94529.1 - 0.0057 16.4 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NAD_kinase PF01513.21 EAX94529.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 ATP-NAD kinase DAGK_acc PF00609.19 EAX94529.1 - 0.029 14.7 0.0 0.077 13.3 0.0 1.7 1 1 0 1 1 1 0 Diacylglycerol kinase accessory domain SNURF PF07192.11 EAX94529.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SNURF/RPN4 protein Beach PF02138.18 EAX94530.1 - 4.1e-44 151.0 11.1 3e-23 82.6 0.1 3.9 2 1 0 3 3 3 2 Beige/BEACH domain PH_BEACH PF14844.6 EAX94530.1 - 9.2e-10 38.5 0.1 1.2e-08 34.9 0.1 2.9 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 EAX94530.1 - 0.00079 19.7 0.3 1.4 9.3 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX94530.1 - 0.0018 19.0 0.0 3.3 8.7 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat SNF5 PF04855.12 EAX94530.1 - 0.025 14.4 5.0 1.2 8.9 0.1 2.5 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 NTase_sub_bind PF08780.11 EAX94530.1 - 0.037 14.0 1.4 0.062 13.3 0.2 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like Syntaxin PF00804.25 EAX94530.1 - 2.5 7.7 6.6 1.2 8.7 2.3 2.2 2 0 0 2 2 2 0 Syntaxin ALIX_LYPXL_bnd PF13949.6 EAX94532.1 - 0.19 11.0 3.6 0.16 11.3 0.7 2.3 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV IZUMO PF15005.6 EAX94532.1 - 0.3 11.6 4.4 1.1 9.8 0.5 3.4 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated GARP PF16731.5 EAX94532.1 - 0.59 9.8 2.3 31 4.2 0.2 3.5 3 1 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Focal_AT PF03623.13 EAX94532.1 - 0.65 10.0 9.4 14 5.7 0.0 4.9 5 2 1 6 6 6 0 Focal adhesion targeting region TPR_1 PF00515.28 EAX94533.1 - 5.7e-09 35.4 1.6 3e-05 23.6 1.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX94533.1 - 1.8e-06 27.6 3.3 7.5e-05 22.5 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX94533.1 - 1.5e-05 24.8 0.4 1.5e-05 24.8 0.4 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX94533.1 - 0.00046 20.0 0.2 0.066 13.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAX94533.1 - 0.00071 19.2 4.4 0.00097 18.8 1.1 2.5 2 1 0 2 2 2 1 TPR repeat Fis1_TPR_C PF14853.6 EAX94533.1 - 0.002 18.2 0.7 0.0046 17.0 0.7 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EAX94533.1 - 0.0029 17.8 2.1 7 7.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAX94533.1 - 0.02 15.4 0.1 0.047 14.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX94533.1 - 0.1 12.9 0.2 2.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX94533.1 - 0.14 13.0 0.0 0.35 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank PF00023.30 EAX94535.1 - 1.2e-47 158.3 11.9 8e-08 32.4 0.1 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX94535.1 - 7e-45 150.9 12.1 4.5e-10 39.9 0.1 8.6 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94535.1 - 1.2e-44 150.8 22.6 3.1e-14 53.3 2.1 4.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX94535.1 - 3.2e-39 132.7 5.9 3.2e-39 132.7 5.9 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX94535.1 - 9.8e-33 111.8 6.1 1.9e-10 40.8 0.1 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94535.1 - 6.8e-32 105.9 23.1 1.2e-05 25.2 0.1 10.1 11 0 0 11 11 11 6 Ankyrin repeat DUF3718 PF12514.8 EAX94535.1 - 0.02 15.0 2.4 73 3.6 0.1 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3718) DUF4100 PF13352.6 EAX94535.1 - 0.021 14.6 4.3 0.3 10.8 1.9 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4100) Bromodomain PF00439.25 EAX94536.1 - 1.2e-08 34.9 3.6 3.5e-08 33.4 0.9 2.4 2 0 0 2 2 2 1 Bromodomain CLTH PF10607.9 EAX94536.1 - 0.048 13.5 1.2 0.084 12.8 1.2 1.5 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SAS-6_N PF16531.5 EAX94536.1 - 0.15 12.6 6.4 1.4 9.5 0.4 2.5 2 1 0 2 2 2 0 Centriolar protein SAS N-terminal Col_cuticle_N PF01484.17 EAX94536.1 - 0.26 11.4 1.2 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Thioredoxin_6 PF13848.6 EAX94537.1 - 0.01 15.7 4.4 3 7.7 0.1 4.0 4 0 0 4 4 4 0 Thioredoxin-like domain DUF4448 PF14610.6 EAX94538.1 - 0.0012 18.6 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2207 PF09972.9 EAX94538.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SCF PF02404.15 EAX94538.1 - 0.0056 16.1 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Stem cell factor NB PF04159.13 EAX94538.1 - 0.0066 16.5 1.0 0.014 15.4 1.0 1.5 1 0 0 1 1 1 1 NB glycoprotein Insulin_TMD PF17870.1 EAX94538.1 - 0.014 15.5 4.1 0.035 14.2 4.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2165 PF09933.9 EAX94538.1 - 0.037 14.1 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) ETRAMP PF09716.10 EAX94538.1 - 0.041 13.9 0.7 0.05 13.7 0.7 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SP_C-Propep PF08999.10 EAX94538.1 - 0.056 13.2 1.3 0.096 12.5 1.3 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PTP_tm PF18861.1 EAX94538.1 - 0.064 13.2 2.6 0.066 13.2 0.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5385 PF17359.2 EAX94538.1 - 0.065 12.8 2.8 0.13 11.8 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 EAX94538.1 - 0.42 10.6 4.6 0.83 9.6 4.6 1.5 1 0 0 1 1 1 0 Syndecan domain Vpu PF00558.19 EAX94538.1 - 3.9 7.3 6.5 3.8 7.4 5.2 1.6 2 0 0 2 2 2 0 Vpu protein IPK PF03770.16 EAX94539.1 - 1.9e-19 70.3 0.0 3.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Gly-zipper_Omp PF13488.6 EAX94540.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX94540.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX94540.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX94540.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94540.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Sec7 PF01369.20 EAX94545.1 - 1.4e-39 135.7 0.1 1.8e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EAX94545.1 - 5.1e-10 39.8 0.1 1.2e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EAX94545.1 - 0.0019 18.4 0.1 0.013 15.8 0.0 2.2 1 1 2 3 3 3 1 Pleckstrin homology domain Wap1 PF16997.5 EAX94545.1 - 0.056 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Wap1 domain DUF648 PF04890.13 EAX94546.1 - 0.049 13.4 0.4 0.056 13.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF4448 PF14610.6 EAX94546.1 - 0.16 11.7 0.8 0.46 10.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PQ-loop PF04193.14 EAX94547.1 - 1.8e-28 98.1 27.8 3e-16 58.9 4.6 3.0 4 0 0 4 4 4 2 PQ loop repeat Myb_DNA-binding PF00249.31 EAX94550.1 - 2.2e-05 24.6 0.0 8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94550.1 - 5.7e-05 23.3 1.8 0.00014 22.0 0.4 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Agouti PF05039.12 EAX94550.1 - 9.8 7.0 5.9 2.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Agouti protein Myb_DNA-binding PF00249.31 EAX94551.1 - 1.9e-19 69.6 8.8 1.1e-07 31.9 0.1 5.4 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94551.1 - 5.9e-14 52.1 12.6 3.6e-05 23.9 0.1 5.1 5 0 0 5 5 5 3 Myb-like DNA-binding domain Orthopox_F7 PF05813.12 EAX94551.1 - 0.035 14.2 0.3 0.13 12.4 0.3 1.9 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Rad60-SLD PF11976.8 EAX94551.1 - 0.054 13.3 0.1 0.29 11.0 0.1 2.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EAX94551.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain I_LWEQ PF01608.17 EAX94552.1 - 2.1e-15 57.3 9.2 2.1e-15 57.3 9.2 7.2 6 2 3 9 9 9 2 I/LWEQ domain Colicin_M PF14859.6 EAX94552.1 - 0.0008 18.6 0.5 0.0074 15.4 0.1 2.7 2 0 0 2 2 2 1 Colicin M DUF1657 PF07870.11 EAX94552.1 - 0.0037 17.1 5.1 2.6 8.0 0.5 5.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1657) DUF4129 PF13559.6 EAX94552.1 - 0.077 13.3 0.3 0.3 11.4 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Speriolin_C PF15059.6 EAX94552.1 - 0.1 12.8 3.9 0.18 11.9 0.2 3.3 3 0 0 3 3 3 0 Speriolin C-terminus XPC-binding PF09280.11 EAX94552.1 - 5.5 6.8 8.1 31 4.4 0.2 4.5 3 0 0 3 3 3 0 XPC-binding domain ACP_PD PF04336.12 EAX94552.1 - 8.7 6.8 8.4 1.5e+02 2.8 0.0 5.8 5 0 0 5 5 5 0 Acyl carrier protein phosphodiesterase Ins_P5_2-kin PF06090.12 EAX94553.1 - 1.3e-59 202.3 0.4 1.5e-59 202.1 0.4 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF896 PF05979.12 EAX94553.1 - 0.035 14.0 0.0 0.67 9.9 0.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Hormone_3 PF00159.18 EAX94553.1 - 1.2 9.3 2.8 24 5.1 0.1 3.0 3 0 0 3 3 3 0 Pancreatic hormone peptide YkyA PF10368.9 EAX94554.1 - 0.0037 16.9 9.1 0.0097 15.6 4.6 2.2 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein DASH_Ask1 PF08655.10 EAX94554.1 - 0.034 14.0 1.2 0.32 10.9 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Ask1 YkuI_C PF10388.9 EAX94554.1 - 0.21 11.4 7.4 0.45 10.3 7.4 1.6 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain Pepsin-I3 PF06394.13 EAX94554.1 - 0.24 11.6 1.9 0.49 10.6 0.5 2.3 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Med26 PF08711.11 EAX94554.1 - 0.42 10.7 3.4 0.26 11.4 0.6 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Med21 PF11221.8 EAX94554.1 - 0.74 10.1 6.8 4.7 7.4 1.5 2.2 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Pkinase PF00069.25 EAX94555.1 - 5.3e-30 104.7 0.0 6.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94555.1 - 1.6e-18 67.0 0.0 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX94555.1 - 1.7e-10 40.3 0.0 2.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX94555.1 - 0.00084 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX94555.1 - 0.0061 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX94555.1 - 0.02 13.8 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EAX94555.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EAX94555.1 - 0.19 11.0 0.0 0.59 9.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Fructosamin_kin PF03881.14 EAX94555.1 - 0.33 10.1 1.9 2.3 7.3 0.0 2.4 3 0 0 3 3 3 0 Fructosamine kinase SVWC PF15430.6 EAX94556.1 - 0.04 14.2 0.4 6 7.2 0.0 2.7 2 0 0 2 2 2 0 Single domain von Willebrand factor type C DUF3391 PF11871.8 EAX94556.1 - 0.39 11.3 3.7 3.3 8.2 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Jnk-SapK_ap_N PF09744.9 EAX94556.1 - 2 8.6 7.7 3 8.1 7.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Phage_B PF02304.15 EAX94557.1 - 1.5 9.2 11.2 5.8 7.3 0.2 4.0 4 0 0 4 4 4 0 Scaffold protein B Ras PF00071.22 EAX94558.1 - 4.6e-44 149.9 0.6 5.4e-44 149.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94558.1 - 3e-31 108.1 0.1 4.2e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94558.1 - 2.9e-17 62.7 0.2 3.5e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX94558.1 - 2e-07 30.6 0.1 2.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX94558.1 - 5.3e-07 29.2 0.1 7.9e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAX94558.1 - 2.5e-06 27.2 0.4 5.4e-06 26.1 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX94558.1 - 2e-05 24.7 0.1 3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX94558.1 - 0.003 17.3 0.6 0.031 14.0 0.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EAX94558.1 - 0.0041 16.3 0.3 0.0097 15.1 0.3 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.23 EAX94558.1 - 0.0064 16.6 0.1 0.011 15.8 0.1 1.4 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EAX94558.1 - 0.0064 16.7 1.0 0.021 15.1 0.2 2.0 2 0 0 2 2 2 1 AAA domain adh_short_C2 PF13561.6 EAX94558.1 - 0.015 14.8 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DLIC PF05783.11 EAX94558.1 - 0.02 13.8 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CPT PF07931.12 EAX94558.1 - 0.043 13.7 0.2 0.079 12.8 0.1 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Attractin PF08037.11 EAX94558.1 - 0.047 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Attractin family AAA_14 PF13173.6 EAX94558.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX94558.1 - 0.068 13.5 0.2 0.11 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Rota_VP4_MID PF17477.2 EAX94558.1 - 0.082 12.3 0.2 0.2 11.0 0.2 1.5 1 1 0 1 1 1 0 Rotavirus VP4 membrane interaction domain MBOAT PF03062.19 EAX94561.1 - 1.1e-06 28.3 17.4 1.1e-06 28.3 17.4 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PHO4 PF01384.20 EAX94562.1 - 0.23 10.4 2.4 0.27 10.3 2.4 1.1 1 0 0 1 1 1 0 Phosphate transporter family Pex24p PF06398.11 EAX94562.1 - 2.8 6.8 5.0 3.1 6.7 4.9 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin PSP PF04046.16 EAX94563.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Dynein_heavy PF03028.15 EAX94564.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.8 2 1 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain LRR_5 PF13306.6 EAX94567.1 - 6e-121 398.0 99.5 8.9e-24 83.9 2.3 7.4 2 1 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94567.1 - 2.2e-22 78.6 6.4 0.0019 17.9 0.0 11.2 7 3 6 13 13 13 6 Leucine rich repeat LRR_4 PF12799.7 EAX94567.1 - 9.2e-07 29.1 14.7 0.0032 17.8 0.1 7.9 6 2 2 8 8 8 1 Leucine Rich repeats (2 copies) CX PF01705.19 EAX94567.1 - 2 9.0 7.8 45 4.7 0.0 5.2 5 0 0 5 5 5 0 CX module Rad60-SLD PF11976.8 EAX94568.1 - 0.00027 20.7 4.1 5.7 6.9 0.0 4.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like RabGAP-TBC PF00566.18 EAX94569.1 - 0.0011 18.6 14.6 0.0029 17.3 14.6 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Gly_rich PF12810.7 EAX94570.1 - 2.3e-29 103.0 44.4 2.3e-29 103.0 44.4 1.7 2 0 0 2 2 1 1 Glycine rich protein Furin-like_2 PF15913.5 EAX94570.1 - 8.1e-07 29.2 24.1 0.00018 21.6 9.7 2.5 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich TMEM154 PF15102.6 EAX94570.1 - 2.4e-05 24.3 2.2 5.2e-05 23.2 2.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAX94570.1 - 0.0028 17.7 0.4 0.0066 16.5 0.4 1.6 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4064 PF13273.6 EAX94570.1 - 0.0089 16.3 0.5 0.023 15.0 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Syndecan PF01034.20 EAX94570.1 - 0.0092 15.9 0.9 0.029 14.3 0.4 2.0 2 0 0 2 2 2 1 Syndecan domain Insulin_TMD PF17870.1 EAX94570.1 - 0.013 15.5 1.0 0.027 14.5 1.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Protocadherin PF08374.11 EAX94570.1 - 0.02 14.9 0.2 0.02 14.9 0.2 2.0 1 1 0 2 2 2 0 Protocadherin Orf78 PF06024.12 EAX94570.1 - 0.037 14.3 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) HRG PF16954.5 EAX94570.1 - 0.07 13.6 0.6 0.15 12.5 0.6 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4711 PF15829.5 EAX94570.1 - 0.083 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Sec3_C PF09763.9 EAX94570.1 - 0.091 11.1 0.3 0.12 10.7 0.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 OppC_N PF12911.7 EAX94570.1 - 0.19 11.7 0.3 0.49 10.4 0.3 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PI3K_1B_p101 PF10486.9 EAX94570.1 - 4.2 5.0 6.9 5.9 4.5 6.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TMEM154 PF15102.6 EAX94571.1 - 0.00022 21.2 6.2 0.0003 20.7 6.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 EAX94571.1 - 0.00049 20.1 0.8 0.00058 19.8 0.8 1.1 1 0 0 1 1 1 1 Rifin DUF5305 PF17231.2 EAX94571.1 - 0.00056 19.4 3.5 0.0009 18.7 3.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) ETRAMP PF09716.10 EAX94571.1 - 0.0013 18.8 1.0 0.0019 18.3 1.0 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) PIRT PF15099.6 EAX94571.1 - 0.0022 17.6 5.4 0.003 17.1 5.0 1.4 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family ASFV_J13L PF05568.11 EAX94571.1 - 0.003 17.4 1.4 0.003 17.4 1.4 1.5 2 0 0 2 2 2 1 African swine fever virus J13L protein DUF4064 PF13273.6 EAX94571.1 - 0.0074 16.5 0.5 0.014 15.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Orf78 PF06024.12 EAX94571.1 - 0.0075 16.6 2.5 0.016 15.5 2.5 1.6 1 1 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 EAX94571.1 - 0.0089 14.8 0.0 0.0091 14.8 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Sec3_C PF09763.9 EAX94571.1 - 0.015 13.7 1.0 0.016 13.6 1.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 HRG PF16954.5 EAX94571.1 - 0.036 14.5 0.1 0.059 13.8 0.1 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Sigma_reg_N PF13800.6 EAX94571.1 - 0.038 14.3 3.3 0.07 13.4 3.3 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syndecan PF01034.20 EAX94571.1 - 0.05 13.5 1.2 0.08 12.9 1.2 1.3 1 0 0 1 1 1 0 Syndecan domain Pox_A14 PF05767.12 EAX94571.1 - 0.051 13.7 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_M56 PF05569.11 EAX94571.1 - 0.065 12.4 0.1 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Viral_Beta_CD PF04530.12 EAX94571.1 - 0.072 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family TRP PF06011.12 EAX94571.1 - 0.089 11.5 0.2 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 EAX94571.1 - 0.1 13.5 0.3 0.18 12.7 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0239 PF06783.11 EAX94571.1 - 0.16 12.2 4.2 0.3 11.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) ECSCR PF15820.5 EAX94571.1 - 0.38 10.6 4.4 0.11 12.3 0.9 1.8 1 1 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FAM163 PF15069.6 EAX94571.1 - 0.48 10.9 2.3 0.39 11.1 0.3 1.8 1 1 1 2 2 2 0 FAM163 family Shisa PF13908.6 EAX94571.1 - 1.9 8.7 7.3 3.9 7.7 1.3 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Furin-like_2 PF15913.5 EAX94572.1 - 0.00069 19.7 24.4 0.037 14.2 6.0 2.4 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich RIFIN PF02009.16 EAX94572.1 - 0.00073 19.5 0.3 0.0011 18.9 0.3 1.3 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 EAX94572.1 - 0.0011 18.9 5.9 0.0023 17.8 5.9 1.6 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAX94572.1 - 0.0023 18.0 0.1 0.0035 17.4 0.1 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF5305 PF17231.2 EAX94572.1 - 0.0029 17.0 3.3 0.0049 16.3 3.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) PIRT PF15099.6 EAX94572.1 - 0.005 16.4 4.1 0.0089 15.6 4.1 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family ASFV_J13L PF05568.11 EAX94572.1 - 0.0061 16.3 1.4 0.012 15.4 1.4 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein Orf78 PF06024.12 EAX94572.1 - 0.011 16.0 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 0 Orf78 (ac78) VSP PF03302.13 EAX94572.1 - 0.016 14.0 22.4 0.049 12.5 22.4 1.7 1 1 0 1 1 1 0 Giardia variant-specific surface protein DUF4064 PF13273.6 EAX94572.1 - 0.027 14.8 0.5 0.062 13.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Pox_A14 PF05767.12 EAX94572.1 - 0.11 12.7 0.8 0.46 10.7 0.4 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HRG PF16954.5 EAX94572.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Sigma_reg_N PF13800.6 EAX94572.1 - 0.16 12.3 3.5 0.33 11.3 3.5 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syndecan PF01034.20 EAX94572.1 - 0.16 11.9 1.4 0.37 10.7 1.4 1.5 1 0 0 1 1 1 0 Syndecan domain UPF0239 PF06783.11 EAX94572.1 - 2.2 8.5 4.5 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) RIFIN PF02009.16 EAX94573.1 - 0.00025 21.1 0.5 0.0003 20.8 0.5 1.1 1 0 0 1 1 1 1 Rifin DUF5305 PF17231.2 EAX94573.1 - 0.00069 19.1 3.5 0.0012 18.4 3.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) ETRAMP PF09716.10 EAX94573.1 - 0.00092 19.2 0.4 0.0013 18.8 0.4 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) ASFV_J13L PF05568.11 EAX94573.1 - 0.0017 18.2 1.4 0.0036 17.1 1.4 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 EAX94573.1 - 0.0017 18.3 8.8 0.0022 17.9 8.5 1.5 1 1 0 1 1 1 1 TMEM154 protein family PIRT PF15099.6 EAX94573.1 - 0.0025 17.4 5.2 0.0032 17.0 4.8 1.4 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family DUF4064 PF13273.6 EAX94573.1 - 0.0073 16.6 0.5 0.017 15.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Orf78 PF06024.12 EAX94573.1 - 0.0084 16.4 2.2 0.018 15.4 2.2 1.6 1 1 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 EAX94573.1 - 0.011 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec3_C PF09763.9 EAX94573.1 - 0.012 14.0 0.6 0.014 13.9 0.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 HRG PF16954.5 EAX94573.1 - 0.04 14.3 0.1 0.071 13.5 0.1 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Sigma_reg_N PF13800.6 EAX94573.1 - 0.05 13.9 3.5 0.099 12.9 3.5 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syndecan PF01034.20 EAX94573.1 - 0.06 13.3 1.1 0.097 12.6 1.1 1.3 1 0 0 1 1 1 0 Syndecan domain Pox_A14 PF05767.12 EAX94573.1 - 0.061 13.5 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_M56 PF05569.11 EAX94573.1 - 0.079 12.1 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Viral_Beta_CD PF04530.12 EAX94573.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family TRP PF06011.12 EAX94573.1 - 0.1 11.3 0.2 0.16 10.7 0.2 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 EAX94573.1 - 0.13 13.2 0.3 0.23 12.4 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 EAX94573.1 - 0.18 12.2 0.6 0.4 11.1 0.0 1.8 2 0 0 2 2 2 0 FAM163 family UPF0239 PF06783.11 EAX94573.1 - 0.21 11.8 4.2 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) ECSCR PF15820.5 EAX94573.1 - 2.6 7.9 6.9 0.1 12.4 0.7 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF2721 PF11026.8 EAX94574.1 - 0.78 9.6 5.6 1.9 8.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Sigma_reg_N PF13800.6 EAX94574.1 - 6.2 7.2 8.2 31 4.9 1.3 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DASH_Spc19 PF08287.11 EAX94576.1 - 0.0041 17.0 4.1 0.0075 16.2 4.1 1.6 1 1 0 1 1 1 1 Spc19 DUF4474 PF14751.6 EAX94576.1 - 0.0083 15.6 0.3 0.013 15.0 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4474) CCDC84 PF14968.6 EAX94576.1 - 0.014 15.0 2.9 0.016 14.8 2.9 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 ER PF01133.17 EAX94576.1 - 0.023 14.7 0.6 0.14 12.1 0.1 2.1 1 1 1 2 2 2 0 Enhancer of rudimentary Exonuc_VII_L PF02601.15 EAX94576.1 - 0.081 12.5 1.6 0.099 12.2 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLATT_5 PF18160.1 EAX94576.1 - 0.16 11.3 1.4 0.2 10.9 1.3 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Podoplanin PF05808.11 EAX94577.1 - 0.041 14.0 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Podoplanin Orthoreo_P10 PF07204.11 EAX94577.1 - 0.096 12.6 3.3 0.13 12.2 0.8 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF3839 PF12943.7 EAX94579.1 - 1.2e-157 522.7 11.1 1.4e-157 522.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX94579.1 - 0.73 10.3 4.7 2 8.9 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AbiJ_NTD4 PF18863.1 EAX94580.1 - 0.026 15.0 0.3 0.06 13.8 0.3 1.7 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAX94580.1 - 0.031 14.4 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 VirK protein DUF641 PF04859.12 EAX94581.1 - 0.031 14.6 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX94581.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor DUF2960 PF11173.8 EAX94582.1 - 0.042 14.3 0.3 0.12 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Ras PF00071.22 EAX94583.1 - 5.8e-38 130.0 0.0 6.8e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94583.1 - 8.2e-28 97.0 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94583.1 - 3.9e-15 55.7 0.0 4.5e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX94583.1 - 3e-05 24.1 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX94583.1 - 0.00016 21.1 0.0 0.00043 19.7 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX94583.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX94583.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EAX94583.1 - 0.079 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAX94583.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EAX94583.1 - 0.16 12.5 0.1 0.38 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain PDEase_I PF00233.19 EAX94584.1 - 2.2e-81 273.1 0.7 4.5e-81 272.1 0.7 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX94584.1 - 1.6e-30 106.4 0.0 4.4e-14 53.3 0.0 5.1 4 1 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX94584.1 - 1.6e-20 73.9 0.0 6.2e-06 26.6 0.0 5.2 5 1 0 5 5 5 4 GAF domain GAF_3 PF13492.6 EAX94584.1 - 4.5e-16 59.4 0.0 1.8e-08 34.8 0.0 4.5 5 0 0 5 5 5 2 GAF domain DUF3369 PF11849.8 EAX94584.1 - 0.17 12.1 1.1 1.2 9.3 0.1 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF3369) Dynein_light PF01221.18 EAX94585.1 - 6.2e-40 135.4 1.9 6.9e-40 135.3 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF515 PF04415.12 EAX94585.1 - 0.028 12.8 0.0 0.033 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) UTP15_C PF09384.10 EAX94586.1 - 0.091 12.4 1.1 1.1 8.9 0.1 3.1 3 0 0 3 3 3 0 UTP15 C terminal Porin_4 PF13609.6 EAX94587.1 - 3.2e-09 37.0 2.3 0.0017 18.2 0.0 3.0 1 1 2 3 3 3 3 Gram-negative porin Usher PF00577.20 EAX94587.1 - 0.013 14.4 0.3 0.031 13.2 0.0 1.6 1 1 1 2 2 2 0 Outer membrane usher protein GRDP-like PF07173.12 EAX94587.1 - 0.24 12.0 12.7 4.2 8.0 0.4 3.9 1 1 3 4 4 4 0 Glycine-rich domain-containing protein-like DUF4816 PF16086.5 EAX94587.1 - 3.8 7.5 21.1 7 6.7 0.5 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4816) TPR_2 PF07719.17 EAX94588.1 - 0.00041 20.2 0.0 1.6 9.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SNF PF00209.18 EAX94588.1 - 0.0065 15.2 1.5 0.011 14.5 1.5 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TPR_1 PF00515.28 EAX94588.1 - 0.0073 16.1 0.2 4.4 7.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX94588.1 - 0.014 15.5 0.1 12 6.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TFCD_C PF12612.8 EAX94588.1 - 0.015 15.2 1.6 0.69 9.7 0.8 3.3 3 1 1 4 4 4 0 Tubulin folding cofactor D C terminal TPR_12 PF13424.6 EAX94588.1 - 0.085 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX94589.1 - 1.9e-55 188.1 0.0 2.3e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94589.1 - 8.7e-28 97.3 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94589.1 - 4e-11 42.8 0.0 5.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX94589.1 - 0.0013 17.8 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAX94589.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 EAX94590.1 - 5.4e-26 91.2 0.0 1.3e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EAX94590.1 - 2.6e-08 34.3 0.0 8.6e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 MyTH4 domain DUF4175 PF13779.6 EAX94590.1 - 0.3 8.9 0.1 0.41 8.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tub PF01167.18 EAX94591.1 - 0.00015 21.6 0.6 0.00028 20.7 0.6 1.8 1 1 0 1 1 1 1 Tub family FAM176 PF14851.6 EAX94591.1 - 2 8.1 5.5 7.7 6.2 5.3 2.0 2 1 1 3 3 3 0 FAM176 family SUI1 PF01253.22 EAX94592.1 - 5.6e-24 84.5 0.8 7.4e-24 84.1 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bromodomain PF00439.25 EAX94593.1 - 0.0002 21.4 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX94593.1 - 0.025 14.7 1.5 0.025 14.7 1.5 2.2 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Dpoe2NT PF12213.8 EAX94593.1 - 0.095 13.0 0.9 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Ank_2 PF12796.7 EAX94597.1 - 1.2e-26 93.1 5.5 9.6e-15 54.9 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94597.1 - 8.1e-24 83.0 0.1 1e-07 32.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX94597.1 - 1.5e-21 76.5 0.7 9.2e-12 45.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94597.1 - 4.5e-19 66.5 0.2 3.4e-07 30.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX94597.1 - 2.9e-12 46.6 0.6 2.3e-07 31.0 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SAB PF04382.13 EAX94597.1 - 0.033 14.3 2.0 7.1 6.8 0.1 3.1 3 0 0 3 3 3 0 SAB domain ThiS-like PF14453.6 EAX94597.1 - 0.035 14.2 0.5 1.7 8.7 0.2 2.3 1 1 1 2 2 2 0 ThiS-like ubiquitin PAZ_siRNAbind PF12212.8 EAX94597.1 - 0.1 12.4 0.1 8.1 6.3 0.0 2.5 1 1 1 2 2 2 0 PAZ domain DUF3696 PF12476.8 EAX94597.1 - 0.16 12.4 0.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) Gly-zipper_Omp PF13488.6 EAX94601.1 - 0.0047 16.9 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX94601.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX94601.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX94601.1 - 0.25 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94601.1 - 0.84 9.8 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PI3_PI4_kinase PF00454.27 EAX94604.1 - 1.5e-51 175.6 1.6 1.3e-49 169.3 0.1 3.5 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EAX94604.1 - 8.4e-14 51.1 0.3 3.5e-13 49.1 0.3 2.2 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EAX94604.1 - 1.5e-12 47.7 8.9 1.7e-11 44.3 0.1 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EAX94604.1 - 1.1e-08 35.4 1.4 4.1e-08 33.6 0.4 2.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FAT PF02259.23 EAX94604.1 - 0.0015 17.8 4.0 0.0015 17.8 4.0 2.6 2 1 0 2 2 2 1 FAT domain HEAT_2 PF13646.6 EAX94604.1 - 0.0062 16.9 0.0 0.25 11.7 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EAX94604.1 - 0.045 14.3 0.9 4.7 7.9 0.2 4.3 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Fe-ADH PF00465.19 EAX94605.1 - 9.3e-110 366.9 0.6 1e-109 366.7 0.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX94605.1 - 1.3e-14 54.6 2.1 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase BKACE PF05853.12 EAX94605.1 - 0.022 14.1 0.0 0.052 12.9 0.1 1.6 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme Metallophos PF00149.28 EAX94606.1 - 2.3e-24 87.1 0.1 3.6e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX94606.1 - 0.0034 17.6 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 EAX94607.1 - 5.8e-27 93.6 2.5 1.8e-12 47.2 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94607.1 - 3.7e-23 81.5 7.2 3.3e-15 56.1 1.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX94607.1 - 0.00014 21.8 2.5 0.068 13.2 0.0 2.7 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX94607.1 - 0.00077 19.3 6.2 0.0017 18.2 2.5 2.5 2 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX94607.1 - 0.0021 18.2 0.7 0.0038 17.4 0.4 1.7 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX94607.1 - 0.0051 16.9 0.1 1.2 9.3 0.0 2.4 1 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pinin_SDK_memA PF04696.13 EAX94607.1 - 0.046 13.8 2.3 0.092 12.8 0.2 2.0 1 1 1 2 2 2 0 pinin/SDK/memA/ protein conserved region UDG PF03167.19 EAX94608.1 - 0.075 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily YmzC PF14157.6 EAX94609.1 - 0.12 12.5 0.6 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 YmzC-like protein B56 PF01603.20 EAX94611.1 - 2.3e-104 349.7 11.5 2.6e-104 349.5 11.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Glyco_transf_9 PF01075.17 EAX94611.1 - 0.063 12.6 0.5 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) XRN_N PF03159.18 EAX94612.1 - 4.8e-53 180.1 0.4 1.4e-50 172.0 0.4 2.2 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAX94612.1 - 1.1e-14 54.3 5.1 1.7e-09 37.1 0.7 2.1 1 1 1 2 2 2 2 Xrn1 helical domain HEAT_2 PF13646.6 EAX94613.1 - 0.0027 18.0 0.0 0.94 9.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EAX94613.1 - 0.019 15.2 1.1 0.36 11.2 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat DnaB_2 PF07261.11 EAX94613.1 - 0.16 11.8 2.5 0.55 10.0 0.2 3.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment NUC173 PF08161.12 EAX94613.1 - 0.18 11.4 3.2 15 5.1 0.1 3.8 4 0 0 4 4 4 0 NUC173 domain Sigma70_ner PF04546.13 EAX94613.1 - 0.96 9.3 7.2 1.8 8.4 4.0 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region TFCD_C PF12612.8 EAX94613.1 - 8 6.2 10.1 13 5.5 0.0 4.7 4 1 1 5 5 5 0 Tubulin folding cofactor D C terminal TPR_MLP1_2 PF07926.12 EAX94614.1 - 0.019 15.0 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX94614.1 - 0.065 13.1 0.1 0.081 12.8 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX94614.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF1664 PF07889.12 EAX94617.1 - 0.016 15.2 4.0 0.016 15.2 4.0 5.7 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) ApoO PF09769.9 EAX94617.1 - 0.039 13.9 4.9 4.3 7.3 0.0 3.8 2 1 1 3 3 3 0 Apolipoprotein O HSBP1 PF06825.12 EAX94617.1 - 0.2 11.6 21.1 1.6 8.6 0.2 5.5 5 0 0 5 5 5 0 Heat shock factor binding protein 1 DUF948 PF06103.11 EAX94617.1 - 10 6.5 23.0 1.8 8.9 0.6 6.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HSP20 PF00011.21 EAX94618.1 - 1.5e-17 63.6 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 EAX94618.1 - 0.00055 20.9 1.1 0.0033 18.4 0.1 2.1 1 1 0 2 2 2 1 CS domain ArsA_HSP20 PF17886.1 EAX94618.1 - 0.00078 19.0 0.1 0.0029 17.1 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 EAX94618.1 - 0.0091 16.1 2.9 0.39 10.9 0.2 2.5 3 0 0 3 3 3 2 FKBP26_C-terminal Collagen_bind_2 PF12904.7 EAX94618.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase DUF3332 PF11810.8 EAX94618.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) VPS9 PF02204.18 EAX94619.1 - 0.00097 19.3 0.2 0.009 16.2 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain TFIID_NTD2 PF04494.15 EAX94619.1 - 0.011 16.0 6.1 0.051 13.8 0.1 2.9 2 1 1 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain CutA1 PF03091.15 EAX94619.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein RE_R_Pab1 PF09522.10 EAX94619.1 - 0.084 13.0 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease HEAT_2 PF13646.6 EAX94620.1 - 1.1e-17 64.2 0.5 1.8e-05 25.1 0.2 6.2 3 3 4 7 7 7 4 HEAT repeats HEAT PF02985.22 EAX94620.1 - 3.5e-14 51.7 10.5 0.058 13.7 0.0 10.2 12 0 0 12 12 12 3 HEAT repeat Adaptin_N PF01602.20 EAX94620.1 - 1.9e-06 26.8 1.0 0.0002 20.0 0.1 2.9 2 1 0 2 2 2 1 Adaptin N terminal region PBECR2 PF18810.1 EAX94620.1 - 0.00065 20.0 0.1 0.003 17.8 0.0 2.1 2 0 0 2 2 2 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 HEAT_EZ PF13513.6 EAX94620.1 - 0.00068 20.1 0.1 5.1 7.7 0.0 5.7 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EAX94620.1 - 0.0038 17.8 1.1 6.2 7.5 0.0 4.5 4 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF1308 PF07000.11 EAX94620.1 - 0.024 14.5 0.3 0.061 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) Arm PF00514.23 EAX94620.1 - 0.063 13.3 0.8 13 6.0 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 EAX94620.1 - 0.1 11.8 0.2 1.6 7.8 0.0 2.5 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Vps39_2 PF10367.9 EAX94621.1 - 7.4e-09 36.0 0.5 2.4e-08 34.4 0.5 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 EAX94621.1 - 0.0081 15.8 0.7 0.028 14.0 0.7 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Npa1 PF11707.8 EAX94621.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal zf-RING_5 PF14634.6 EAX94621.1 - 0.011 15.6 4.4 0.061 13.3 4.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAX94621.1 - 0.012 15.4 2.4 0.012 15.4 2.4 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX94621.1 - 0.033 14.1 4.2 0.074 12.9 1.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 EAX94621.1 - 0.033 14.5 0.1 0.089 13.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 EAX94621.1 - 0.093 13.1 7.2 0.13 12.6 1.4 3.2 3 0 0 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 EAX94621.1 - 2.2 8.4 9.7 0.48 10.5 1.0 3.6 4 0 0 4 4 4 0 RING-type zinc-finger Tetraspanin PF00335.20 EAX94622.1 - 3.9e-08 33.3 5.2 3.9e-08 33.3 5.2 2.0 1 1 1 2 2 2 1 Tetraspanin family COX1 PF00115.20 EAX94622.1 - 0.00071 18.6 5.4 0.0016 17.3 4.4 1.8 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF3671 PF12420.8 EAX94622.1 - 0.001 19.1 0.3 0.001 19.1 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function EI24 PF07264.11 EAX94622.1 - 0.0014 18.9 2.3 0.0037 17.5 2.3 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TNFR_16_TM PF18422.1 EAX94622.1 - 0.0035 17.3 1.3 0.0035 17.3 1.3 3.9 4 1 0 4 4 4 1 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3681 PF12442.8 EAX94622.1 - 0.013 16.0 3.6 0.062 13.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) EphA2_TM PF14575.6 EAX94622.1 - 0.07 14.0 2.5 9.6 7.2 0.0 3.7 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF5643 PF18705.1 EAX94622.1 - 0.17 11.8 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) DUF3464 PF11947.8 EAX94622.1 - 0.57 9.9 2.2 1 9.1 2.2 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Gemini_mov PF01708.16 EAX94622.1 - 0.77 9.6 0.0 0.77 9.6 0.0 2.3 3 0 0 3 3 3 0 Geminivirus putative movement protein FtsX PF02687.21 EAX94622.1 - 3.1 8.3 20.0 3.1 8.3 3.0 2.4 1 1 1 2 2 2 0 FtsX-like permease family PSP PF04046.16 EAX94623.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAX94624.1 - 0.068 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HSP20 PF00011.21 EAX94625.1 - 1.1e-18 67.3 0.1 1.2e-18 67.1 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAX94625.1 - 3.9e-06 26.3 0.0 7.3e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA IL33 PF15095.6 EAX94625.1 - 0.038 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin 33 FKBP26_C PF18046.1 EAX94625.1 - 0.14 12.3 0.7 11 6.2 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal VWA_3 PF13768.6 EAX94626.1 - 6e-20 71.8 0.0 1.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX94626.1 - 1.4e-13 51.4 0.0 4e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EAX94626.1 - 1.6e-13 50.8 0.1 4.1e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EAX94626.1 - 6.3e-08 33.2 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAX94626.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ldh_1_N PF00056.23 EAX94627.1 - 9e-29 100.4 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX94627.1 - 3.1e-21 76.0 0.0 5.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pkinase PF00069.25 EAX94629.1 - 5.3e-73 245.6 0.1 6.8e-73 245.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94629.1 - 1.4e-42 145.8 0.0 1.9e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX94629.1 - 4.3e-08 33.6 0.5 1.1e-07 32.3 0.5 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EAX94629.1 - 1.2e-06 28.1 0.0 3.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX94629.1 - 0.00052 18.9 0.0 0.0009 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EAX94629.1 - 0.00085 18.4 0.4 0.0014 17.6 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PH_9 PF15410.6 EAX94629.1 - 0.011 16.1 0.1 0.43 11.0 0.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 EAX94629.1 - 0.013 15.9 1.6 0.24 11.9 0.2 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Kdo PF06293.14 EAX94629.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX94629.1 - 0.07 12.8 0.1 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX94629.1 - 0.22 11.4 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CCSAP PF15748.5 EAX94630.1 - 2.6 8.2 38.1 3.2 7.9 38.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Ank_2 PF12796.7 EAX94631.1 - 2.6e-66 220.2 18.4 1e-15 58.0 0.7 4.7 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94631.1 - 6.6e-40 135.0 4.0 2.2e-10 40.9 0.1 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94631.1 - 1.3e-27 95.4 5.4 1.3e-08 35.0 0.1 6.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94631.1 - 2e-24 83.0 7.0 0.00011 22.3 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EAX94631.1 - 3.8e-21 74.5 4.7 6e-05 23.3 0.0 7.3 9 0 0 9 9 9 4 Ankyrin repeat Peptidase_M48_N PF16491.5 EAX94632.1 - 9.1e-49 165.8 18.0 1.9e-47 161.5 13.1 2.3 2 0 0 2 2 2 2 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAX94632.1 - 2.2e-26 92.8 0.4 5.7e-26 91.5 0.0 1.9 1 1 1 2 2 2 1 Peptidase family M48 SprT-like PF10263.9 EAX94632.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 EAX94632.1 - 0.67 9.1 9.1 0.24 10.6 5.7 1.9 2 1 0 2 2 2 0 BlaR1 peptidase M56 Myb_DNA-binding PF00249.31 EAX94633.1 - 1.5e-15 57.1 0.3 2.3e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94633.1 - 2e-11 43.9 6.3 1.1e-08 35.2 3.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX94633.1 - 0.21 11.5 6.4 0.05 13.5 0.8 2.5 1 1 2 3 3 3 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 EAX94634.1 - 1e-14 54.4 0.2 2.2e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94634.1 - 4.8e-11 42.7 6.3 1.2e-08 35.1 3.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain GLEYA PF10528.9 EAX94635.1 - 1.9e-05 25.0 3.2 2.3e-05 24.7 1.2 2.3 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 EAX94635.1 - 0.031 14.1 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 PA14 domain Big_9 PF17963.1 EAX94635.1 - 0.097 13.4 0.2 0.097 13.4 0.2 4.0 4 0 0 4 4 4 0 Bacterial Ig domain DUF3974 PF13120.6 EAX94635.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) UPF0016 PF01169.19 EAX94636.1 - 9.6 6.6 10.2 0.56 10.6 0.4 2.8 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 Pkinase PF00069.25 EAX94637.1 - 5.5e-06 25.9 0.0 7.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EAX94638.1 - 3.2e-64 216.8 0.0 3.5e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94638.1 - 2.3e-32 112.3 0.0 2.8e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX94638.1 - 0.00053 19.0 0.0 0.00068 18.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX94638.1 - 0.00054 19.4 0.0 0.012 15.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EAX94638.1 - 0.0084 16.1 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX94638.1 - 0.027 13.5 0.1 0.3 10.1 0.0 2.0 1 1 1 2 2 2 0 Seadornavirus VP7 DUF1387 PF07139.11 EAX94638.1 - 0.033 13.9 0.8 0.044 13.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PAS PF00989.25 EAX94639.1 - 0.036 14.1 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_2 PF08446.11 EAX94639.1 - 0.061 14.0 0.0 0.35 11.5 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 EAX94639.1 - 0.07 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 PAS domain Di19_C PF14571.6 EAX94639.1 - 0.81 10.2 3.6 0.68 10.5 0.5 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal HSP70 PF00012.20 EAX94642.1 - 5.3e-93 312.2 6.3 9e-91 304.9 2.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAX94642.1 - 6.2e-14 51.6 0.4 1.5e-13 50.3 0.4 1.6 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 EAX94642.1 - 1.9e-05 24.1 0.2 0.00029 20.2 0.0 2.2 2 0 0 2 2 2 1 StbA protein DDR PF08841.10 EAX94642.1 - 0.003 16.6 0.0 0.006 15.6 0.0 1.5 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Ppx-GppA PF02541.16 EAX94642.1 - 0.01 15.3 0.1 0.024 14.1 0.1 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Lipoprotein_17 PF04200.12 EAX94642.1 - 0.047 14.0 8.5 4.7 7.6 0.4 3.8 3 0 0 3 3 3 0 Lipoprotein associated domain Hydantoinase_A PF01968.18 EAX94642.1 - 0.05 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Pyrophosphatase PF00719.19 EAX94642.1 - 0.055 13.3 0.0 4.7 7.0 0.0 3.0 2 1 1 3 3 3 0 Inorganic pyrophosphatase DUF1828 PF08861.10 EAX94642.1 - 0.073 13.4 0.1 27 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF1828 FtsA PF14450.6 EAX94642.1 - 0.19 12.2 0.9 0.6 10.6 0.9 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Pox_A32 PF04665.12 EAX94643.1 - 4.5e-05 23.0 3.1 5.1e-05 22.9 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX94643.1 - 0.0041 17.2 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX94643.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX94643.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2802 PF10975.8 EAX94645.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PI3K_1B_p101 PF10486.9 EAX94646.1 - 3.9e-05 21.7 10.9 3.9e-05 21.7 10.9 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EAX94646.1 - 0.017 13.7 13.4 0.019 13.5 13.4 1.0 1 0 0 1 1 1 0 Macoilin family Dsh_C PF12316.8 EAX94646.1 - 0.12 12.8 9.6 0.19 12.1 9.6 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal LMBR1 PF04791.16 EAX94646.1 - 0.97 8.3 4.3 1.2 7.9 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GAGA_bind PF06217.12 EAX94646.1 - 1.1 9.4 15.4 1.8 8.8 15.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ndc1_Nup PF09531.10 EAX94646.1 - 1.5 7.4 10.5 1.7 7.2 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 EAX94646.1 - 1.8 8.3 28.4 2.7 7.7 28.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 EAX94646.1 - 2.5 7.8 23.6 6e+03 -3.1 23.6 3.0 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 GREB1 PF15782.5 EAX94646.1 - 3 4.9 19.2 3.5 4.6 19.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 EAX94646.1 - 3.3 8.2 15.1 5.1 7.6 15.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.13 EAX94646.1 - 5.7 6.5 29.0 7.6 6.0 29.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Shisa PF13908.6 EAX94646.1 - 6.7 6.9 10.7 12 6.0 0.5 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PFK PF00365.20 EAX94647.1 - 6.2e-95 317.8 0.6 7.2e-95 317.6 0.6 1.0 1 0 0 1 1 1 1 Phosphofructokinase Gly_rich PF12810.7 EAX94650.1 - 8.6e-38 130.6 19.7 1e-37 130.4 19.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX94651.1 - 1.3e-32 113.7 17.8 1.6e-32 113.4 17.8 1.0 1 0 0 1 1 1 1 Glycine rich protein WXG100 PF06013.12 EAX94653.1 - 3.5e-05 23.9 2.4 0.029 14.6 0.3 3.2 2 1 1 3 3 3 2 Proteins of 100 residues with WXG NDUFB11 PF17250.2 EAX94653.1 - 0.046 14.3 0.5 0.14 12.9 0.1 2.0 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit DUF3365 PF11845.8 EAX94653.1 - 0.5 10.7 4.7 1.2 9.5 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) Peptidase_S49_N PF08496.10 EAX94653.1 - 0.87 9.6 6.6 1.4 8.9 6.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMPIT PF07851.13 EAX94653.1 - 1.3 8.2 5.1 1.5 8.0 4.2 1.5 1 1 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.13 EAX94653.1 - 1.3 9.4 13.6 1.5 9.2 4.8 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4375 PF14300.6 EAX94653.1 - 4 7.7 11.2 0.95 9.7 1.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) YabA PF06156.13 EAX94653.1 - 8 7.2 8.8 3.3 8.4 0.9 2.6 1 1 2 3 3 3 0 Initiation control protein YabA Pkinase PF00069.25 EAX94654.1 - 1.1e-29 103.6 0.0 1.6e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94654.1 - 1.2e-14 54.3 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX94654.1 - 8.5e-09 34.7 0.0 1.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX94654.1 - 1.5e-05 25.1 0.0 0.0035 17.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAX94654.1 - 0.0039 16.6 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX94654.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GrpE PF01025.19 EAX94655.1 - 0.0072 16.0 4.9 0.0084 15.8 3.0 2.0 1 1 0 1 1 1 1 GrpE zf-PARP PF00645.18 EAX94655.1 - 0.04 14.8 2.5 0.21 12.5 0.1 2.5 1 1 1 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region P4Ha_N PF08336.11 EAX94655.1 - 0.07 13.1 5.7 0.22 11.5 1.8 2.5 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DrrA_P4M PF14860.6 EAX94655.1 - 0.091 12.6 3.0 0.63 9.9 0.4 3.3 2 2 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain EAP30 PF04157.16 EAX94655.1 - 0.11 11.8 1.2 0.57 9.4 1.2 2.3 1 1 0 1 1 1 0 EAP30/Vps36 family CoA_transf_3 PF02515.17 EAX94655.1 - 0.13 11.3 0.6 0.17 10.9 0.6 1.2 1 0 0 1 1 1 0 CoA-transferase family III NYD-SP28_assoc PF14775.6 EAX94655.1 - 0.15 12.2 2.5 3.5 7.8 0.0 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain TBCA PF02970.16 EAX94655.1 - 0.43 11.0 7.5 0.079 13.3 2.2 2.6 2 1 0 2 2 2 0 Tubulin binding cofactor A DLIC PF05783.11 EAX94656.1 - 0.14 10.9 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3671 PF12420.8 EAX94657.1 - 0.13 12.4 1.3 16 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function EGF_3 PF12947.7 EAX94657.1 - 2.1 8.6 18.9 4.5 7.6 11.6 2.8 2 1 0 2 2 2 0 EGF domain Chromo PF00385.24 EAX94658.1 - 4.7e-15 55.2 3.5 1.9e-14 53.3 3.5 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAX94658.1 - 1.4e-10 41.1 0.5 0.00093 19.2 0.1 2.9 2 0 0 2 2 2 2 Chromo shadow domain Pkinase_Tyr PF07714.17 EAX94659.1 - 4.4e-54 183.5 0.0 9.3e-54 182.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX94659.1 - 8.5e-50 169.6 0.0 1.5e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAX94659.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1077 PF06417.12 EAX94660.1 - 0.013 15.5 0.2 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) APG6 PF04111.12 EAX94661.1 - 2.5e-15 56.9 0.2 5.5e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Apg6 BARA domain zinc_ribbon_10 PF10058.9 EAX94661.1 - 0.46 10.2 2.3 13 5.6 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein MULE PF10551.9 EAX94662.1 - 4.5e-11 43.0 0.0 9.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX94662.1 - 0.086 13.2 0.9 0.46 10.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAX94662.1 - 0.11 12.6 3.6 0.21 11.7 3.6 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF4065 PF13274.6 EAX94662.1 - 0.13 13.2 0.2 2.2 9.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF4107 PF13389.6 EAX94663.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX94664.1 - 0.0089 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX94665.1 - 2.7e-156 518.2 14.0 3.4e-156 517.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX94665.1 - 0.23 11.8 2.0 0.62 10.4 0.9 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX94665.1 - 0.39 11.3 6.0 0.47 11.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX94665.1 - 1.7 9.2 6.9 5.7 7.5 0.6 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ICAT PF06384.11 EAX94666.1 - 0.045 14.0 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT TALPID3 PF15324.6 EAX94666.1 - 0.053 11.2 6.1 0.07 10.8 6.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target LIN37 PF15306.6 EAX94666.1 - 0.06 13.6 2.9 0.09 13.0 2.9 1.2 1 0 0 1 1 1 0 LIN37 Pneumo_att_G PF05539.11 EAX94666.1 - 0.61 9.6 4.4 0.86 9.1 4.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Trypan_PARP PF05887.11 EAX94666.1 - 1.5 8.8 5.7 7.4 6.6 5.6 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Rad60-SLD PF11976.8 EAX94667.1 - 0.00012 21.9 0.2 0.00022 21.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAX94667.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family LptF_LptG PF03739.14 EAX94667.1 - 0.84 8.4 2.6 1.9 7.3 2.4 1.6 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Herpes_UL73 PF03554.13 EAX94668.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Apolipoprotein PF01442.18 EAX94669.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 EAX94671.1 - 0.0084 15.7 18.5 2.2 7.8 1.7 3.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX94672.1 - 2e-125 417.1 7.0 2.4e-125 416.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX94672.1 - 0.047 13.9 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 PDEase_I PF00233.19 EAX94673.1 - 1.1e-42 146.5 2.8 1.1e-42 146.4 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX94673.1 - 1.2e-39 135.9 0.0 6.3e-18 65.7 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX94673.1 - 4.6e-28 98.2 0.0 3.2e-07 30.7 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 EAX94673.1 - 3e-16 59.9 0.0 9.2e-05 22.8 0.0 4.4 4 0 0 4 4 4 3 GAF domain FliG_N PF14842.6 EAX94673.1 - 0.011 16.3 2.5 0.037 14.6 2.5 1.9 1 0 0 1 1 1 0 FliG N-terminal domain Vpu PF00558.19 EAX94674.1 - 0.079 12.7 1.3 0.16 11.7 1.3 1.4 1 0 0 1 1 1 0 Vpu protein HECT PF00632.25 EAX94675.1 - 8.3e-26 91.2 0.9 5.9e-22 78.5 0.0 3.9 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) DUF5010_C PF18099.1 EAX94675.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 DUF5010 C-terminal domain Pinin_SDK_N PF04697.13 EAX94676.1 - 0.042 14.5 23.6 6 7.5 0.8 5.2 1 1 6 7 7 7 0 pinin/SDK conserved region SpoIIE PF07228.12 EAX94677.1 - 1.9e-06 28.0 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EAX94677.1 - 2.6e-06 27.2 0.0 0.007 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EAX94677.1 - 0.00044 20.0 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF5028 PF16431.5 EAX94677.1 - 0.037 14.0 0.2 0.082 12.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5028) EF-hand_7 PF13499.6 EAX94678.1 - 2.8e-22 78.9 3.8 5.4e-11 42.8 0.2 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX94678.1 - 3.2e-18 63.8 10.8 0.00051 19.4 0.1 4.7 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 EAX94678.1 - 3.2e-18 64.0 5.4 1.2e-05 24.9 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX94678.1 - 8.5e-13 47.9 7.3 1.4e-05 24.8 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EAX94678.1 - 1.2e-08 35.1 0.7 0.0002 21.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EAX94678.1 - 0.00017 20.9 5.4 4.4 7.0 0.0 4.5 4 0 0 4 4 4 3 EF hand DUF3349 PF11829.8 EAX94678.1 - 0.0023 18.7 0.4 2.1 9.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3349) TerB PF05099.13 EAX94678.1 - 0.02 14.8 0.2 3.9 7.4 0.0 2.6 1 1 0 2 2 2 0 Tellurite resistance protein TerB DUF1456 PF07308.13 EAX94678.1 - 0.14 12.5 0.4 7 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EspA PF03433.13 EAX94678.1 - 0.15 11.9 1.2 1 9.2 0.1 2.3 2 1 1 3 3 3 0 EspA-like secreted protein HeLo PF14479.6 EAX94679.1 - 0.011 15.6 1.0 0.022 14.6 1.0 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation SAM_LFY PF01698.16 EAX94679.1 - 0.071 13.1 0.3 0.21 11.5 0.3 1.8 1 1 0 1 1 1 0 Floricaula / Leafy protein SAM domain MscS_porin PF12795.7 EAX94679.1 - 0.13 11.8 5.7 0.2 11.2 3.2 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain APG6_N PF17675.1 EAX94679.1 - 0.13 12.8 6.6 0.14 12.7 5.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5082 PF16888.5 EAX94679.1 - 0.16 12.3 7.7 0.29 11.4 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DHR10 PF18595.1 EAX94679.1 - 2.7 8.1 10.5 0.81 9.8 5.0 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain UPF0449 PF15136.6 EAX94679.1 - 9.5 6.8 5.7 7.2 7.1 2.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3839 PF12943.7 EAX94680.1 - 3.9e-155 514.4 12.2 4.7e-155 514.1 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX94680.1 - 0.086 13.1 0.3 2 8.7 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX94680.1 - 0.76 10.3 6.0 4.8 7.7 0.4 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX94682.1 - 1.6e-28 98.5 12.2 1.6e-28 98.5 12.2 4.1 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX94682.1 - 0.037 13.8 0.3 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Gp5_C PF06715.12 EAX94682.1 - 0.29 11.4 1.6 1.3e+02 3.1 0.2 4.1 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) YmaF PF12788.7 EAX94682.1 - 1.2 9.7 13.6 17 6.1 6.0 3.5 2 2 0 2 2 2 0 YmaF family TMP PF05017.14 EAX94684.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX94685.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP UCH PF00443.29 EAX94686.1 - 9.4e-51 172.8 2.9 9.4e-51 172.8 2.9 3.8 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX94686.1 - 9.3e-20 71.4 2.5 9.3e-20 71.4 2.5 4.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase VWA_3 PF13768.6 EAX94687.1 - 1.1e-18 67.6 0.0 1.8e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX94687.1 - 7.7e-16 58.8 0.0 1.5e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EAX94687.1 - 1.1e-12 48.1 0.0 3.4e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EAX94687.1 - 9.7e-12 45.5 0.0 2.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAX94687.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 EAX94687.1 - 0.15 12.2 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Gly-zipper_Omp PF13488.6 EAX94688.1 - 0.0056 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAX94688.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAX94688.1 - 0.079 12.2 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX94688.1 - 0.33 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94688.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX94690.1 - 9.2e-05 22.0 3.7 0.00017 21.2 3.7 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX94690.1 - 0.0056 16.7 1.0 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX94690.1 - 0.0093 15.6 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1722 PF08349.11 EAX94690.1 - 0.22 11.8 3.2 0.24 11.7 1.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) ABC_tran PF00005.27 EAX94692.1 - 0.00045 20.7 0.0 0.0013 19.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAX94692.1 - 0.013 15.3 0.1 0.028 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MULE PF10551.9 EAX94694.1 - 4.7e-10 39.8 0.1 1.1e-09 38.5 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX94694.1 - 0.0081 15.0 0.2 0.017 14.0 0.2 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX94694.1 - 0.011 15.4 0.3 0.054 13.2 0.2 1.9 1 1 1 2 2 2 0 Transposase FAR1 PF03101.15 EAX94694.1 - 0.092 13.5 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain zf-RING_2 PF13639.6 EAX94695.1 - 9.3e-14 51.5 9.2 1.7e-13 50.6 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX94695.1 - 2.8e-10 39.9 9.5 6.2e-10 38.8 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX94695.1 - 1.6e-09 37.4 6.1 4.1e-09 36.0 6.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EAX94695.1 - 6e-09 36.1 8.8 1.6e-08 34.7 8.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAX94695.1 - 1.2e-08 34.7 6.7 2e-08 34.0 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EAX94695.1 - 8.2e-08 32.0 9.3 1.5e-07 31.1 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX94695.1 - 4.8e-07 29.7 4.2 1.3e-06 28.3 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAX94695.1 - 7.7e-06 25.7 5.1 1.5e-05 24.8 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAX94695.1 - 0.00011 22.2 4.4 0.00033 20.7 4.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EAX94695.1 - 0.0004 19.9 5.4 0.00074 19.1 5.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EAX94695.1 - 0.0011 18.7 5.0 0.002 17.9 5.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EAX94695.1 - 0.0018 18.1 6.0 0.0038 17.1 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EAX94695.1 - 0.018 15.2 5.9 0.059 13.5 5.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EAX94695.1 - 0.054 13.6 9.1 0.1 12.7 9.1 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EAX94695.1 - 0.13 12.2 7.7 0.04 13.8 2.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EAX94695.1 - 0.14 12.4 5.4 0.41 10.8 5.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EAX94695.1 - 0.45 10.7 4.8 0.89 9.7 4.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 EAX94695.1 - 1.3 9.4 6.6 2.3 8.6 6.6 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EAX94695.1 - 1.4 9.0 5.1 1.1 9.3 2.4 2.3 2 0 0 2 2 1 0 Zinc-finger PHD PF00628.29 EAX94695.1 - 3.2 7.7 7.8 6.1 6.8 7.8 1.5 1 0 0 1 1 1 0 PHD-finger Arf PF00025.21 EAX94696.1 - 2.9e-25 88.7 0.0 3.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX94696.1 - 6.7e-06 26.3 0.0 9.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAX94696.1 - 7.5e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX94696.1 - 0.0022 17.2 0.6 1.4 8.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EAX94696.1 - 0.05 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX94696.1 - 0.059 12.7 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region VWA_2 PF13519.6 EAX94698.1 - 2.4e-09 37.8 0.0 5.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EAX94698.1 - 0.0013 18.6 0.2 0.0021 17.9 0.2 1.4 1 0 0 1 1 1 1 Ssl1-like YcgR_2 PF12945.7 EAX94699.1 - 0.028 14.6 0.8 14 5.9 0.0 3.0 2 1 1 3 3 3 0 Flagellar protein YcgR PI3_PI4_kinase PF00454.27 EAX94700.1 - 1.9e-53 181.8 3.4 3.7e-53 180.9 0.0 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAX94700.1 - 5.3e-22 78.5 3.6 5.3e-22 78.5 3.6 3.6 3 1 0 3 3 3 1 FAT domain FRB_dom PF08771.11 EAX94700.1 - 1e-11 45.1 5.4 1e-11 45.1 1.3 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EAX94700.1 - 1.1e-09 37.9 1.3 7.6e-09 35.2 0.0 3.0 3 0 0 3 3 3 1 FATC domain DUF3385 PF11865.8 EAX94700.1 - 0.00039 20.4 7.1 0.00058 19.8 0.0 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) HEAT PF02985.22 EAX94700.1 - 0.00067 19.7 0.0 11 6.6 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EAX94700.1 - 0.0063 16.9 0.0 4.7 7.7 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats Ank_2 PF12796.7 EAX94701.1 - 7.1e-28 97.0 3.4 1e-11 45.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94701.1 - 3.8e-24 82.1 0.9 0.00021 21.4 0.0 6.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAX94701.1 - 3.8e-24 84.7 0.3 7.5e-07 29.6 0.1 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94701.1 - 1.9e-19 69.5 0.5 1.5e-07 31.5 0.1 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX94701.1 - 2.9e-19 68.6 0.5 0.00037 20.8 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Histone PF00125.24 EAX94702.1 - 3.3e-07 30.7 0.1 4e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 EAX94703.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX94703.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX94703.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_S8 PF00082.22 EAX94704.1 - 4.3e-10 39.3 0.3 1e-09 38.1 0.3 1.7 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAX94704.1 - 4.4e-10 39.4 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Beta_helix PF13229.6 EAX94705.1 - 2.5e-35 121.7 56.5 1e-12 48.2 2.0 5.4 4 1 2 6 6 6 4 Right handed beta helix region NosD PF05048.13 EAX94705.1 - 1.2e-20 73.8 48.0 9.5e-07 28.3 4.0 5.1 2 1 2 5 5 5 4 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EAX94705.1 - 0.015 15.1 30.2 0.81 9.5 5.2 5.4 3 2 2 5 5 5 0 Pectate lyase superfamily protein Peptidase_M24 PF00557.24 EAX94706.1 - 6.6e-57 192.6 0.1 8.4e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAX94706.1 - 1.9e-21 76.1 0.0 7e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF563 PF04577.14 EAX94707.1 - 1.4e-19 71.0 0.1 1.6e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PSP PF04046.16 EAX94708.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94709.1 - 0.73 10.7 5.1 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX94710.1 - 0.027 14.9 0.4 0.056 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX94710.1 - 0.18 11.8 1.6 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3839 PF12943.7 EAX94712.1 - 1.5e-156 519.0 13.7 1.9e-156 518.7 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX94712.1 - 0.093 13.3 4.4 0.17 12.5 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX94712.1 - 1.1 9.8 6.9 2.2 8.8 0.6 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX94713.1 - 0.00054 20.5 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX94713.1 - 0.01 15.4 0.6 0.11 12.0 0.2 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX94713.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Na_sulph_symp PF00939.19 EAX94716.1 - 3.8e-32 112.0 37.2 5.4e-32 111.4 37.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAX94716.1 - 5.4e-21 75.1 59.2 4.7e-18 65.4 34.6 2.6 1 1 1 3 3 3 2 Citrate transporter SPX PF03105.19 EAX94716.1 - 1e-06 28.9 16.5 4.7e-05 23.5 11.8 2.7 1 1 0 2 2 2 2 SPX domain DUF2839 PF10999.8 EAX94716.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) EST1 PF10374.9 EAX94716.1 - 0.75 10.4 3.0 1.4 9.5 3.0 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 ACP_PD PF04336.12 EAX94716.1 - 1.2 9.6 4.2 12 6.3 0.8 2.3 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase PSP PF04046.16 EAX94717.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX94718.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX94720.1 - 1.3e-24 86.1 8.8 1.3e-24 86.1 8.8 3.3 2 1 1 3 3 3 1 Phage tail repeat like DUF3417 PF11897.8 EAX94720.1 - 0.04 14.4 0.9 0.16 12.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) PH_TFIIH PF08567.11 EAX94720.1 - 0.088 13.1 0.6 3.1 8.2 0.1 2.7 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain DUF4116 PF13475.6 EAX94720.1 - 0.1 12.3 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2203 PF09969.9 EAX94720.1 - 6.5 7.5 7.5 2.5 8.8 1.7 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3839 PF12943.7 EAX94721.1 - 6.5e-155 513.6 14.2 8.7e-155 513.2 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX94721.1 - 0.032 14.1 1.0 0.097 12.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX94721.1 - 0.053 13.8 0.7 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Tup N-terminal MitMem_reg PF13012.6 EAX94721.1 - 0.15 12.5 0.7 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX94721.1 - 0.32 11.5 4.5 1.6 9.2 0.3 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX94721.1 - 0.38 11.1 4.9 1.1 9.6 0.1 3.5 3 1 0 4 4 4 0 PRD domain KilA-N PF04383.13 EAX94722.1 - 8.1e-41 138.4 0.4 1.7e-40 137.3 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX94722.1 - 0.0081 16.8 0.0 0.034 14.8 0.0 2.0 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX94723.1 - 1.1e-06 28.3 2.5 1.1e-06 28.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX94723.1 - 3.3e-05 24.2 0.3 0.00025 21.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX94723.1 - 4.2e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX94723.1 - 0.00016 21.8 3.4 0.00038 20.5 3.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX94723.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX94723.1 - 0.0016 18.3 0.6 0.0032 17.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX94723.1 - 0.0018 18.0 0.5 0.012 15.3 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX94723.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX94723.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX94723.1 - 0.09 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX94723.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX94723.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX94725.1 - 1.3e-57 193.8 4.4 1.4e-57 193.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Glyco_transf_28 PF03033.20 EAX94727.1 - 7.3 6.6 10.0 0.54 10.3 0.4 3.9 4 0 0 4 4 4 0 Glycosyltransferase family 28 N-terminal domain DUF3447 PF11929.8 EAX94728.1 - 0.00013 21.9 4.7 0.00079 19.3 4.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) DUF5402 PF17393.2 EAX94728.1 - 0.00019 21.4 0.0 0.14 12.1 0.0 2.8 3 0 0 3 3 3 2 Family of unknown function (DUF5402) TEX12 PF15219.6 EAX94728.1 - 0.055 13.8 0.3 0.16 12.3 0.3 1.8 1 0 0 1 1 1 0 Testis-expressed 12 Orthopox_A47 PF06334.11 EAX94728.1 - 0.067 12.5 2.4 0.06 12.6 0.4 1.9 2 0 0 2 2 2 0 Orthopoxvirus A47 protein Myb_DNA-binding PF00249.31 EAX94729.1 - 8.9e-26 89.8 3.3 7.3e-15 54.9 0.8 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94729.1 - 3e-21 75.4 6.0 4e-15 55.8 1.9 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX94729.1 - 8.3e-06 25.8 0.5 0.11 12.6 0.0 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX94729.1 - 3e-05 23.8 0.6 0.031 14.2 0.0 2.5 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX94729.1 - 0.01 16.0 0.2 0.02 15.1 0.1 1.6 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX94729.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4108 PF13390.6 EAX94731.1 - 5.5e-63 211.2 5.8 6.1e-63 211.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX94733.1 - 2.1e-19 69.9 5.2 1.1e-09 38.7 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94733.1 - 1.6e-12 46.4 8.7 0.022 15.3 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EAX94733.1 - 5.8e-10 39.5 2.9 0.0013 19.2 0.0 3.9 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94733.1 - 1.1e-06 28.8 0.9 0.53 10.7 0.0 4.8 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94733.1 - 0.00092 19.6 3.0 2.8 8.5 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeat SICA_C PF12879.7 EAX94733.1 - 0.0015 18.6 19.9 0.2 11.7 0.1 6.1 2 1 4 6 6 6 4 SICA C-terminal inner membrane domain MIF4G_like PF09088.11 EAX94733.1 - 0.22 11.3 6.7 2.7 7.7 0.1 3.6 1 1 2 3 3 3 0 MIF4G like Phage_int_SAM_2 PF12834.7 EAX94733.1 - 7.8 7.3 10.6 2.2e+02 2.6 0.1 6.4 2 1 5 8 8 8 0 Phage integrase, N-terminal PhoLip_ATPase_C PF16212.5 EAX94734.1 - 3.4e-26 92.5 28.0 3.4e-26 92.5 28.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EAX94734.1 - 3.1e-08 33.3 0.0 3.1e-08 33.3 0.0 4.4 4 1 1 5 5 5 1 E1-E2 ATPase TMEM154 PF15102.6 EAX94734.1 - 0.028 14.3 2.8 0.47 10.3 0.1 2.6 2 0 0 2 2 2 0 TMEM154 protein family FtsJ PF01728.19 EAX94734.1 - 0.034 14.3 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PLAC8 PF04749.17 EAX94734.1 - 0.15 13.1 0.8 0.42 11.6 0.1 2.3 2 0 0 2 2 2 0 PLAC8 family Spc7 PF08317.11 EAX94736.1 - 0.00038 19.5 29.1 0.00038 19.5 29.1 15.2 1 1 13 15 15 15 7 Spc7 kinetochore protein CDC24 PF06395.11 EAX94736.1 - 2.4 8.5 11.0 0.072 13.4 0.3 4.3 3 0 0 3 3 3 0 CDC24 Calponin Profilin PF00235.19 EAX94737.1 - 1.1e-19 70.9 0.0 1.2e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Profilin Myb_DNA-binding PF00249.31 EAX94738.1 - 6e-25 87.2 0.1 1.3e-13 50.9 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94738.1 - 2.3e-19 69.4 0.2 1.3e-12 47.8 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX94738.1 - 0.001 18.9 8.2 0.26 11.2 0.1 3.1 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 EAX94738.1 - 0.012 15.6 3.1 0.54 10.3 0.0 3.2 1 1 2 3 3 3 0 SLIDE EF-hand_5 PF13202.6 EAX94739.1 - 1.4e-05 24.4 0.2 3.7e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EAX94739.1 - 9.7e-05 21.7 1.4 0.00028 20.2 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EAX94739.1 - 0.00023 20.9 0.3 0.0038 17.0 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EAX94739.1 - 0.00064 20.1 0.6 0.00064 20.1 0.6 3.7 3 1 0 3 3 3 1 EF-hand domain pair Glyco_transf_24 PF18404.1 EAX94740.1 - 7.7e-125 415.7 0.8 1.6e-124 414.7 0.8 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EAX94740.1 - 1.4e-29 103.8 1.4 3.8e-29 102.4 0.4 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EAX94740.1 - 4.4e-15 55.8 1.3 3.7e-14 52.8 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EAX94740.1 - 4.5e-13 49.5 0.2 4.6e-12 46.2 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EAX94740.1 - 4e-07 30.2 0.3 0.00023 21.2 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAX94740.1 - 6.5e-06 25.9 0.2 7.1e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 UDP-g_GGTase PF06427.11 EAX94740.1 - 1.9e-05 24.7 0.0 8.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase LigT_PEase PF02834.16 EAX94740.1 - 0.045 13.9 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 LigT like Phosphoesterase Hamartin PF04388.12 EAX94742.1 - 2.6 6.6 26.2 4.7 5.7 26.2 1.3 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EAX94743.1 - 1.9e-74 250.4 0.1 2.7e-74 249.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94743.1 - 6.4e-45 153.4 0.0 9.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94743.1 - 7.9e-07 28.7 0.0 5.3e-05 22.7 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EAX94743.1 - 6.7e-06 26.2 0.3 0.00011 22.2 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX94743.1 - 0.00095 18.2 0.3 0.0026 16.7 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX94743.1 - 0.00097 18.5 0.2 0.0016 17.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX94743.1 - 0.0028 17.3 2.3 0.004 16.8 0.2 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAX94743.1 - 0.0081 15.8 0.4 0.18 11.4 0.0 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PapD_N PF00345.20 EAX94745.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX94745.1 - 0.063 13.3 0.4 0.095 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX94746.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94746.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX94747.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX94748.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX94748.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX94749.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX94749.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PqiA PF04403.13 EAX94750.1 - 8.9e-11 41.9 32.4 5.8e-07 29.5 3.8 3.4 4 0 0 4 4 4 2 Paraquat-inducible protein A DUF2572 PF10833.8 EAX94750.1 - 0.036 13.8 0.2 0.075 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) CCDC32 PF14989.6 EAX94750.1 - 0.064 13.3 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Tub PF01167.18 EAX94752.1 - 8.6e-06 25.7 2.0 1.9e-05 24.6 0.0 2.3 2 2 0 3 3 3 1 Tub family YjbH PF06082.11 EAX94752.1 - 7.1 5.3 6.4 9.6 4.9 6.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH FancD2 PF14631.6 EAX94752.1 - 9.3 3.5 9.7 13 3.0 9.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ank_2 PF12796.7 EAX94754.1 - 1.6e-158 515.7 50.8 2.4e-18 66.5 0.7 11.3 1 1 12 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94754.1 - 4.2e-104 339.7 15.5 4.6e-09 36.6 0.0 15.9 8 5 10 18 18 18 17 Ankyrin repeats (many copies) Ank PF00023.30 EAX94754.1 - 1e-94 307.2 29.8 3.5e-05 24.0 0.0 21.0 21 0 0 21 21 21 20 Ankyrin repeat Ank_5 PF13857.6 EAX94754.1 - 2.7e-92 301.6 18.5 1.2e-08 35.0 0.0 18.2 3 3 16 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94754.1 - 4.3e-86 272.4 12.1 0.00015 21.9 0.0 21.3 21 0 0 21 21 21 18 Ankyrin repeat YfmQ PF10787.9 EAX94754.1 - 1e-05 25.3 0.7 9.9 5.9 0.0 6.7 5 1 3 8 8 8 1 Uncharacterised protein from bacillus cereus group DUF3083 PF11281.8 EAX94754.1 - 0.00012 21.6 3.4 6.2 6.1 0.1 5.5 4 1 1 6 6 6 2 Protein of unknown function (DUF3083) EPSP_synthase PF00275.20 EAX94754.1 - 0.14 10.8 2.7 14 4.3 0.1 4.3 4 1 1 5 5 5 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Phage_T7_Capsid PF05396.11 EAX94754.1 - 0.14 12.5 7.3 73 3.7 0.0 6.5 7 2 0 7 7 7 0 Phage T7 capsid assembly protein RabGAP-TBC PF00566.18 EAX94756.1 - 2.6e-08 33.8 2.0 4e-08 33.2 2.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Flp_N PF03930.14 EAX94756.1 - 0.15 12.1 1.2 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus LRR_5 PF13306.6 EAX94757.1 - 3.1e-09 36.9 3.1 4.7e-09 36.3 3.1 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) PDH_E1_M PF17831.1 EAX94757.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain Ank_2 PF12796.7 EAX94758.1 - 9.5e-72 237.6 52.7 9.7e-15 54.9 4.0 6.6 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94758.1 - 9.1e-50 166.4 18.3 4.2e-08 33.6 0.0 9.9 4 1 8 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX94758.1 - 4.1e-49 163.0 19.9 2.8e-08 33.8 0.1 9.8 10 0 0 10 10 10 9 Ankyrin repeat DUF3447 PF11929.8 EAX94758.1 - 1.4e-40 137.0 4.7 1.4e-40 137.0 4.7 4.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX94758.1 - 4e-36 118.9 30.3 6.7e-06 26.1 0.1 11.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 EAX94758.1 - 4.7e-33 112.8 13.9 3.5e-10 39.9 0.2 7.3 3 2 5 8 8 8 6 Ankyrin repeats (many copies) ERG2_Sigma1R PF04622.12 EAX94758.1 - 0.0046 16.3 0.1 5.2 6.3 0.0 3.4 2 1 1 3 3 3 2 ERG2 and Sigma1 receptor like protein Ribosomal_S6 PF01250.17 EAX94758.1 - 0.057 13.7 3.8 29 5.0 0.0 4.3 2 1 3 5 5 5 0 Ribosomal protein S6 CCDC84 PF14968.6 EAX94758.1 - 0.19 11.3 2.1 1.6 8.3 2.1 2.3 1 1 0 1 1 1 0 Coiled coil protein 84 YppF PF14178.6 EAX94759.1 - 0.0054 16.6 0.6 0.016 15.1 0.6 1.8 1 0 0 1 1 1 1 YppF-like protein HAD_2 PF13419.6 EAX94760.1 - 1.8e-14 54.3 0.0 2.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX94760.1 - 1.3e-10 41.9 0.1 1.1e-09 38.9 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAX94760.1 - 3.8e-07 30.7 0.0 5.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase IBP39 PF11422.8 EAX94761.1 - 1.1e-60 204.4 3.5 1.6e-60 203.9 3.5 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 EAX94761.1 - 3.8e-19 69.0 1.5 7.5e-19 68.0 0.8 1.8 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Cbl_N2 PF02761.14 EAX94761.1 - 0.029 15.1 0.4 0.097 13.4 0.1 2.1 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain WD40 PF00400.32 EAX94762.1 - 0.00032 21.4 7.0 2.2 9.3 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.6 EAX94762.1 - 0.01 15.5 0.0 4.7 6.7 0.0 2.8 1 1 1 3 3 3 0 PQQ-like domain PQQ_3 PF13570.6 EAX94762.1 - 0.011 16.2 1.5 62 4.3 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain Med21 PF11221.8 EAX94763.1 - 0.0024 18.2 2.7 0.13 12.5 3.0 2.0 1 1 1 2 2 2 2 Subunit 21 of Mediator complex Roughex PF06020.11 EAX94763.1 - 0.012 14.7 0.3 0.013 14.6 0.3 1.0 1 0 0 1 1 1 0 Drosophila roughex protein FapA PF03961.13 EAX94763.1 - 0.02 13.6 2.6 0.022 13.4 2.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A HEPN_SAV2148 PF18725.1 EAX94763.1 - 0.069 12.6 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 SAV2148-like HEPN PspB PF06667.12 EAX94763.1 - 0.13 12.3 1.8 4.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Phage shock protein B Maf1 PF09174.10 EAX94764.1 - 0.54 10.4 9.5 0.46 10.6 3.5 2.4 2 1 0 2 2 2 0 Maf1 regulator TraE PF05309.11 EAX94765.1 - 0.0017 17.8 0.7 0.0017 17.8 0.7 2.0 2 0 0 2 2 2 1 TraE protein DUF19 PF01579.18 EAX94765.1 - 0.025 14.4 4.6 0.041 13.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DUF1192 PF06698.11 EAX94765.1 - 0.049 13.7 7.4 0.29 11.2 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Tweety PF04906.13 EAX94765.1 - 0.11 11.1 1.8 0.22 10.1 1.8 1.5 1 0 0 1 1 1 0 Tweety ADIP PF11559.8 EAX94765.1 - 0.15 12.2 32.0 0.081 13.0 1.5 3.9 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 EAX94765.1 - 0.18 10.7 26.0 4.2 6.1 25.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 EAX94765.1 - 0.36 11.0 27.5 0.16 12.2 10.0 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAX94765.1 - 0.59 9.4 15.0 0.69 9.2 12.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EAX94765.1 - 0.67 10.4 15.5 9.5 6.7 0.1 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 EAX94765.1 - 0.81 10.1 3.8 0.5 10.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) XhlA PF10779.9 EAX94765.1 - 1.3 9.2 12.4 2 8.7 1.1 4.3 3 1 1 4 4 4 0 Haemolysin XhlA Cep57_CLD_2 PF14197.6 EAX94765.1 - 1.4 9.0 23.8 0.19 11.9 0.8 4.7 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 ABC_tran_CTD PF16326.5 EAX94765.1 - 1.9 8.8 26.3 1 9.7 1.4 4.6 4 2 2 6 6 6 0 ABC transporter C-terminal domain Uds1 PF15456.6 EAX94765.1 - 2.1 8.5 17.4 1.1 9.4 7.5 3.3 1 1 1 2 2 2 0 Up-regulated During Septation Cob_adeno_trans PF01923.18 EAX94765.1 - 2.2 8.4 12.3 6.7 6.8 0.5 3.2 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Tropomyosin_1 PF12718.7 EAX94765.1 - 4 7.6 27.4 0.36 11.0 4.8 3.4 2 2 1 3 3 3 0 Tropomyosin like LPP PF04728.13 EAX94765.1 - 5.1 7.6 17.9 2 8.9 0.6 5.0 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Radical_SAM_N PF08497.10 EAX94765.1 - 8.6 5.5 7.7 17 4.5 7.7 1.7 1 1 0 1 1 1 0 Radical SAM N-terminal Methyltransf_31 PF13847.6 EAX94766.1 - 9.4e-22 77.4 0.1 1.5e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX94766.1 - 1.4e-15 57.7 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX94766.1 - 3.8e-15 56.4 0.0 7.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAX94766.1 - 3.3e-10 39.7 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAX94766.1 - 4.3e-09 37.0 0.0 7.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX94766.1 - 2.5e-08 34.0 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAX94766.1 - 0.00021 21.2 0.1 0.00071 19.5 0.1 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase DOT1 PF08123.13 EAX94766.1 - 0.00045 19.8 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EAX94766.1 - 0.003 17.3 0.1 0.0061 16.3 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EAX94766.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EAX94766.1 - 0.05 13.1 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 EAX94766.1 - 0.054 13.6 0.0 0.085 13.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EAX94766.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 EAX94767.1 - 2.9e-44 149.0 6.5 3.9e-14 52.5 0.1 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX94767.1 - 5.2e-34 116.3 5.1 1.5e-13 50.8 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX94767.1 - 2.7e-08 33.6 0.1 0.00087 19.1 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX94767.1 - 0.0002 21.5 0.1 0.11 12.7 0.0 3.2 2 1 1 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAX94767.1 - 0.00031 20.9 0.6 0.053 13.7 0.1 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX94767.1 - 0.0034 17.4 0.1 1.1 9.2 0.0 2.9 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX94767.1 - 0.028 14.5 0.1 8 6.6 0.0 3.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX94767.1 - 0.12 12.8 1.5 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2203 PF09969.9 EAX94768.1 - 8.3 7.2 7.9 1.2 9.9 0.4 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Abhydrolase_1 PF00561.20 EAX94769.1 - 3.5e-20 72.7 0.0 4.4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX94769.1 - 4.8e-12 45.7 0.0 5.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX94769.1 - 2.7e-07 31.4 0.0 3.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EAX94769.1 - 6.3e-07 28.4 0.0 8.1e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 EAX94769.1 - 4.6e-05 23.3 0.0 6.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 EAX94769.1 - 0.00035 20.4 0.9 0.016 14.9 0.2 2.1 1 1 1 2 2 2 1 PGAP1-like protein Peptidase_S28 PF05577.12 EAX94769.1 - 0.0023 16.8 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase PF00756.20 EAX94769.1 - 0.0047 16.6 0.0 0.0091 15.7 0.0 1.4 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.7 EAX94769.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1057 PF06342.12 EAX94769.1 - 0.018 14.1 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 EAX94769.1 - 0.028 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Spo12 PF05032.12 EAX94770.1 - 0.5 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family GPS2_interact PF15784.5 EAX94771.1 - 0.023 15.1 0.9 0.029 14.8 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX94771.1 - 0.12 11.4 0.2 0.12 11.3 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX94772.1 - 0.028 14.6 0.1 0.035 14.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein ACP_PD PF04336.12 EAX94773.1 - 0.047 14.1 0.1 1.1 9.7 0.1 3.2 3 1 1 4 4 4 0 Acyl carrier protein phosphodiesterase LRR_5 PF13306.6 EAX94774.1 - 9.1e-77 255.2 64.4 4e-28 98.0 12.1 4.0 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94774.1 - 1.1e-12 47.6 3.2 0.39 10.5 2.4 6.5 5 3 3 8 8 8 5 Leucine rich repeat OstA PF03968.14 EAX94774.1 - 0.14 12.3 0.1 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 OstA-like protein LRR_5 PF13306.6 EAX94775.1 - 7.4e-17 61.5 1.8 7.7e-17 61.4 0.9 1.4 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94775.1 - 0.00015 21.4 0.0 0.00099 18.8 0.0 2.0 1 1 1 2 2 2 1 Leucine rich repeat Ank_2 PF12796.7 EAX94776.1 - 0.04 14.5 0.2 0.59 10.7 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) RasGEF_N PF00618.20 EAX94776.1 - 7.2 6.9 9.6 2.7 8.3 0.4 3.2 3 0 0 3 3 3 0 RasGEF N-terminal motif Ank_2 PF12796.7 EAX94777.1 - 8.5e-09 35.9 0.2 0.017 15.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94777.1 - 7.6e-06 25.9 0.5 0.72 10.6 0.0 5.7 5 1 1 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EAX94777.1 - 9.6e-05 22.9 1.0 1.2 9.8 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) LRR_5 PF13306.6 EAX94778.1 - 6.8e-120 394.6 73.0 1.7e-24 86.2 6.5 7.8 4 3 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94778.1 - 2.6e-30 104.0 11.7 0.001 18.8 0.1 10.0 6 3 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EAX94778.1 - 0.0036 17.7 28.2 0.21 12.1 0.2 9.4 5 2 6 11 11 11 3 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EAX94779.1 - 3.6e-49 167.5 0.0 7.3e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94779.1 - 6e-47 160.1 0.0 1.2e-46 159.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX94779.1 - 0.0018 17.1 0.1 0.0032 16.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX94779.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX94779.1 - 0.044 12.7 0.3 0.28 10.1 0.1 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Casc1 PF12366.8 EAX94779.1 - 0.064 12.8 2.8 0.07 12.7 1.2 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Mcl1_mid PF12341.8 EAX94780.1 - 3.5e-69 233.4 0.0 9.9e-68 228.6 0.0 2.7 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EAX94780.1 - 0.00089 19.5 0.0 0.081 13.2 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3201 PF11447.8 EAX94781.1 - 0.036 13.6 1.0 0.1 12.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3201) DUF3447 PF11929.8 EAX94782.1 - 8.8e-11 41.6 6.0 2e-07 30.9 1.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94782.1 - 1.4e-07 32.0 0.4 0.00017 22.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94782.1 - 1e-05 25.5 0.1 0.00052 20.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX94782.1 - 0.002 18.6 0.2 0.013 16.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94782.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Toxin_R_bind_C PF07951.12 EAX94783.1 - 0.028 14.1 4.0 0.077 12.6 0.5 2.6 2 1 1 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding Herpes_IE2_3 PF03361.14 EAX94783.1 - 0.029 14.2 1.1 0.63 9.9 0.2 2.4 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 HEAT PF02985.22 EAX94783.1 - 0.15 12.4 0.2 3.1 8.3 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat PPP5 PF08321.12 EAX94783.1 - 0.54 10.6 8.2 2.3 8.6 0.9 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region RICTOR_N PF14664.6 EAX94784.1 - 0.0016 17.5 2.8 0.0074 15.3 0.0 3.1 1 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term UNC45-central PF11701.8 EAX94784.1 - 1.1 9.2 4.0 8.6 6.3 0.2 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central NT5C PF06941.12 EAX94785.1 - 1.7e-19 70.4 0.0 2.1e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.6 EAX94785.1 - 0.0035 17.4 0.0 0.0049 17.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAX94785.1 - 0.026 14.6 0.0 0.7 10.0 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX94785.1 - 0.032 14.5 0.0 0.16 12.2 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EAX94785.1 - 0.089 12.4 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) INCENP_ARK-bind PF03941.15 EAX94786.1 - 4.5e-15 55.3 1.0 4.5e-15 55.3 1.0 2.8 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Ank_4 PF13637.6 EAX94788.1 - 5.7e-61 202.1 10.9 1.1e-12 48.2 0.2 8.1 3 1 7 10 10 10 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94788.1 - 1.1e-52 176.6 18.8 4.3e-16 59.3 0.2 6.4 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94788.1 - 1e-50 168.0 7.6 1.5e-08 34.7 0.0 8.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX94788.1 - 1.8e-43 146.0 5.7 7.1e-13 48.5 0.0 6.6 3 1 3 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94788.1 - 3.6e-42 137.5 13.1 1.7e-06 27.9 0.0 9.7 10 0 0 10 10 10 7 Ankyrin repeat DUF3447 PF11929.8 EAX94788.1 - 9.2e-33 112.0 6.8 9.2e-33 112.0 6.8 4.4 4 2 0 4 4 4 1 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAX94788.1 - 0.0098 15.6 1.8 0.018 14.7 1.8 1.5 1 0 0 1 1 1 1 Coiled coil protein 84 Mic1 PF07035.12 EAX94788.1 - 0.011 15.5 0.5 10 5.8 0.0 4.0 2 1 2 4 4 4 0 Colon cancer-associated protein Mic1-like DUF3718 PF12514.8 EAX94788.1 - 0.018 15.1 4.2 38 4.5 0.0 5.1 4 1 2 6 6 6 0 Protein of unknown function (DUF3718) RL PF17797.1 EAX94788.1 - 0.043 13.8 5.1 20 5.2 0.1 5.0 5 0 0 5 5 5 0 RL domain PAZ_siRNAbind PF12212.8 EAX94788.1 - 0.75 9.6 10.0 7.9 6.3 0.2 5.4 2 2 4 7 7 7 0 PAZ domain WD40 PF00400.32 EAX94789.1 - 5.3e-10 39.7 10.9 0.0046 17.8 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94789.1 - 0.0013 19.0 0.0 0.065 13.5 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PMT PF02366.18 EAX94790.1 - 2.1e-29 102.9 6.5 2.1e-29 102.9 6.5 3.2 2 2 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX94790.1 - 7.8e-26 90.9 17.8 7.8e-26 90.9 17.8 3.0 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 EAX94790.1 - 0.00015 22.0 7.6 0.00015 22.0 7.6 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RCC1 PF00415.18 EAX94791.1 - 1e-16 61.3 0.1 0.00028 21.4 0.0 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAX94791.1 - 1.8e-08 33.9 9.0 0.018 14.8 0.1 6.0 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 EAX94791.1 - 0.01 15.8 0.1 0.044 13.8 0.1 2.2 1 0 0 1 1 1 0 Beta-propeller repeat PSP PF04046.16 EAX94792.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Glycos_transf_1 PF00534.20 EAX94794.1 - 2e-32 112.1 0.1 3.1e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAX94794.1 - 1.8e-15 57.5 0.0 2.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAX94794.1 - 2.1e-10 40.8 0.2 3.8e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Thioredoxin_6 PF13848.6 EAX94795.1 - 0.0014 18.6 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EAX94795.1 - 0.019 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Med17 PF10156.9 EAX94796.1 - 0.0011 17.8 0.3 0.0015 17.4 0.3 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Pkinase_Tyr PF07714.17 EAX94797.1 - 1.4e-43 149.1 0.0 4.5e-43 147.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX94797.1 - 1.1e-39 136.4 1.1 3.4e-39 134.8 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain DNApol3-delta_C PF09115.10 EAX94797.1 - 0.013 16.0 1.4 0.013 16.0 1.4 2.9 3 1 1 4 4 4 0 DNA polymerase III, delta subunit, C terminal Spo12 PF05032.12 EAX94798.1 - 0.095 12.6 2.2 0.095 12.6 2.2 2.4 3 0 0 3 3 3 0 Spo12 family Gly-zipper_Omp PF13488.6 EAX94799.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX94799.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94799.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif LRR_5 PF13306.6 EAX94800.1 - 6.3e-73 242.8 71.2 2.1e-26 92.4 21.2 4.1 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94800.1 - 2.5e-10 40.0 32.7 0.36 10.6 0.0 9.8 5 3 6 11 11 11 7 Leucine rich repeat DUF5477 PF17571.2 EAX94800.1 - 0.023 14.9 2.6 1.6 9.0 0.0 4.3 5 1 1 6 6 6 0 Family of unknown function (DUF5477) DUF5014 PF16406.5 EAX94800.1 - 0.3 11.4 1.3 6.6 7.1 0.1 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF5014) Neil1-DNA_bind PF09292.10 EAX94800.1 - 6.3 6.9 14.9 57 3.8 0.0 6.5 6 0 0 6 6 6 0 Endonuclease VIII-like 1, DNA bind PRA-PH PF01503.17 EAX94801.1 - 0.17 12.4 2.3 5.1 7.6 3.5 2.2 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Ank PF00023.30 EAX94803.1 - 6e-72 235.2 17.0 5.2e-07 29.8 0.1 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_2 PF12796.7 EAX94803.1 - 2.1e-70 233.3 52.5 8.1e-16 58.4 2.8 7.8 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94803.1 - 6.1e-69 227.6 22.0 6.3e-09 36.2 0.1 12.5 3 1 10 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94803.1 - 3.3e-60 192.9 23.2 2.8e-05 24.2 0.1 13.5 13 1 1 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 EAX94803.1 - 1.2e-54 181.6 22.4 4.9e-10 39.5 0.6 8.9 5 1 6 11 11 11 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94803.1 - 1.3e-34 118.0 7.8 1.3e-34 118.0 7.8 5.9 5 1 2 7 7 7 2 Domain of unknown function (DUF3447) DUF5064 PF16703.5 EAX94803.1 - 8.7e-05 23.0 4.5 2.1 8.9 0.1 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF5064) ApbA_C PF08546.11 EAX94803.1 - 0.54 10.5 3.7 4.2 7.6 0.1 4.0 3 1 2 5 5 5 0 Ketopantoate reductase PanE/ApbA C terminal Ank_2 PF12796.7 EAX94804.1 - 4.3e-19 68.9 0.2 3.5e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94804.1 - 3e-18 65.9 0.0 7.9e-10 39.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94804.1 - 3.5e-16 57.6 0.0 5e-05 23.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX94804.1 - 2.4e-14 53.2 0.0 3.6e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94804.1 - 6.1e-10 39.1 0.1 0.0049 17.3 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat DUF4108 PF13390.6 EAX94807.1 - 6.1e-77 256.4 12.7 7e-77 256.2 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAX94808.1 - 0.0057 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX94808.1 - 0.26 10.5 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX94808.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX94808.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Proteasome PF00227.26 EAX94809.1 - 1.1e-49 168.5 0.0 1.3e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAX94809.1 - 1.7e-05 24.4 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nnf1 PF03980.14 EAX94810.1 - 7.1e-09 36.0 6.3 4.8e-08 33.4 6.3 2.4 1 1 1 2 2 2 1 Nnf1 Baculo_PEP_C PF04513.12 EAX94810.1 - 0.021 14.9 1.6 0.16 12.0 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ran-binding PF05508.11 EAX94810.1 - 0.023 13.7 2.8 0.025 13.6 1.9 1.4 1 1 0 1 1 1 0 RanGTP-binding protein Laminin_II PF06009.12 EAX94810.1 - 0.037 14.0 2.1 0.037 14.0 2.1 1.9 2 1 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 EAX94810.1 - 0.094 13.0 8.3 1 9.7 1.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 EAX94810.1 - 0.24 11.9 5.8 0.65 10.5 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2205 PF10224.9 EAX94810.1 - 0.29 11.2 4.4 6.3 6.9 0.2 2.9 2 1 1 3 3 3 0 Short coiled-coil protein Rab_bind PF16704.5 EAX94810.1 - 0.32 11.0 3.9 0.21 11.6 1.4 2.1 2 1 0 2 2 2 0 Rab binding domain YpjP PF14005.6 EAX94810.1 - 0.36 10.9 3.4 0.63 10.1 0.1 2.0 2 0 0 2 2 2 0 YpjP-like protein YlqD PF11068.8 EAX94810.1 - 0.45 10.9 8.1 0.091 13.1 2.0 2.3 2 1 0 2 2 2 0 YlqD protein GAT PF03127.14 EAX94810.1 - 0.57 10.5 6.3 0.45 10.9 1.5 2.3 2 0 0 2 2 2 0 GAT domain Noelin-1 PF12308.8 EAX94810.1 - 0.67 10.0 4.4 0.18 11.8 1.2 1.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein MIEAP PF16026.5 EAX94810.1 - 0.67 10.1 4.3 4.8 7.3 1.6 2.0 1 1 1 2 2 2 0 Mitochondria-eating protein Val_tRNA-synt_C PF10458.9 EAX94810.1 - 0.93 9.8 8.9 0.21 11.9 2.2 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm ZapB PF06005.12 EAX94810.1 - 2.2 8.8 12.3 0.94 10.0 4.9 2.8 3 0 0 3 3 3 0 Cell division protein ZapB TcdB_N PF12918.7 EAX94810.1 - 3.1 8.2 10.2 4.6 7.6 0.2 3.5 3 1 0 4 4 4 0 TcdB toxin N-terminal helical domain Ank_4 PF13637.6 EAX94811.1 - 2.2e-47 158.8 6.3 4.7e-12 46.2 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX94811.1 - 1.1e-43 145.8 5.3 3e-07 30.6 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 EAX94811.1 - 3.8e-38 129.9 14.2 4e-14 53.0 0.9 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94811.1 - 7.8e-32 108.9 4.8 5.8e-10 39.2 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94811.1 - 5.2e-31 103.2 4.1 1.9e-05 24.7 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat SAB PF04382.13 EAX94811.1 - 0.0032 17.5 4.3 29 4.8 0.1 4.8 5 0 0 5 5 5 0 SAB domain MetallophosN PF16371.5 EAX94811.1 - 0.0044 17.3 0.3 9.5 6.6 0.0 4.3 1 1 4 5 5 5 1 N terminal of Calcineurin-like phosphoesterase PrpR_N PF06506.11 EAX94811.1 - 0.015 14.8 0.2 2.9 7.5 0.0 3.1 4 1 1 5 5 5 0 Propionate catabolism activator DUF756 PF05506.12 EAX94811.1 - 0.081 13.8 0.8 3.4 8.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF756) DUF406 PF04175.12 EAX94811.1 - 0.15 12.5 0.6 0.46 11.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF406) DUF4760 PF15956.5 EAX94811.1 - 0.2 11.8 2.6 0.22 11.7 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) UMP1 PF05348.11 EAX94812.1 - 9.4e-12 45.2 0.0 1.1e-11 45.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF4271 PF14093.6 EAX94813.1 - 0.0027 17.7 3.1 0.0027 17.7 3.1 5.7 4 1 2 6 6 6 1 Domain of unknown function (DUF4271) PAS PF00989.25 EAX94813.1 - 0.041 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold LRR_5 PF13306.6 EAX94814.1 - 8.4e-128 420.2 70.6 3.9e-31 107.7 8.6 7.2 4 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94814.1 - 8.8e-28 95.9 0.4 0.00038 20.2 0.1 10.2 8 2 3 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 EAX94814.1 - 1.7e-07 31.5 9.1 1.6 9.3 0.0 8.6 6 3 2 9 9 9 2 Leucine Rich repeats (2 copies) Adaptin_N PF01602.20 EAX94816.1 - 9.9e-31 106.9 15.9 1.5e-30 106.3 15.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EAX94816.1 - 0.00097 19.5 0.1 0.033 14.6 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats Tfb5 PF06331.12 EAX94816.1 - 0.23 11.5 8.1 9.1 6.3 4.0 2.8 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 HEAT PF02985.22 EAX94816.1 - 0.24 11.8 0.8 1.5e+02 3.0 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 EAX94816.1 - 0.62 10.1 11.6 9.6 6.2 0.5 4.6 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Utp12 PF04003.12 EAX94817.1 - 0.065 13.5 1.1 0.25 11.6 0.0 2.5 3 0 0 3 3 3 0 Dip2/Utp12 Family DUF3150 PF11348.8 EAX94817.1 - 0.081 12.1 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) TcpS PF17456.2 EAX94817.1 - 0.095 12.8 0.4 0.34 10.9 0.4 1.9 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S DUF2362 PF10154.9 EAX94818.1 - 0.023 13.7 7.1 0.036 13.0 7.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Pox_A32 PF04665.12 EAX94820.1 - 3e-07 30.1 3.2 4.5e-07 29.6 3.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX94820.1 - 0.0045 16.7 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX94820.1 - 0.045 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX94820.1 - 0.063 13.0 0.1 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX94820.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX94820.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX94820.1 - 0.43 10.8 8.6 5.6 7.2 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAX94821.1 - 1.3e-60 203.5 9.1 1.4e-60 203.3 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Beta_helix PF13229.6 EAX94822.1 - 1.1 9.1 11.2 3.6 7.4 11.2 1.9 1 1 0 1 1 1 0 Right handed beta helix region BTB PF00651.31 EAX94823.1 - 1.6e-19 70.2 2.1 2.8e-19 69.4 2.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain F5_F8_type_C PF00754.25 EAX94823.1 - 0.0033 17.5 2.4 0.0059 16.7 2.4 1.3 1 0 0 1 1 1 1 F5/8 type C domain Ras PF00071.22 EAX94824.1 - 1.2e-41 142.0 0.1 1.4e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94824.1 - 2.4e-32 111.7 0.0 3.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94824.1 - 2e-16 59.9 0.0 2.4e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EAX94824.1 - 1e-06 28.3 0.1 6.3e-06 25.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EAX94824.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAX94824.1 - 1.1e-06 28.8 0.1 2.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EAX94824.1 - 1.4e-06 28.3 0.1 0.046 13.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX94824.1 - 1.8e-06 27.7 0.0 0.00027 20.5 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX94824.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX94824.1 - 0.00036 20.0 0.0 0.00073 19.0 0.0 1.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX94824.1 - 0.00043 20.0 0.1 0.078 12.7 0.1 2.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX94824.1 - 0.0089 15.3 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Septin MMR_HSR1_Xtn PF16897.5 EAX94824.1 - 0.014 15.3 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 EAX94824.1 - 0.081 13.3 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ENTH PF01417.20 EAX94825.1 - 1.2e-32 112.5 0.2 2e-32 111.9 0.2 1.3 1 0 0 1 1 1 1 ENTH domain Peptidase_M8 PF01457.16 EAX94826.1 - 1.5e-11 43.7 0.0 2.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EAX94827.1 - 4.7e-18 65.2 0.0 9e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin DUF1325 PF07039.11 EAX94828.1 - 2e-21 76.4 0.7 3.3e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EAX94828.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EAX94828.1 - 0.00099 19.1 0.0 0.0022 18.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Ras PF00071.22 EAX94829.1 - 3.7e-47 159.9 0.4 4.3e-47 159.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94829.1 - 3.8e-28 98.1 0.1 6.1e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94829.1 - 3.2e-14 52.8 0.1 3.7e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX94829.1 - 9.4e-07 28.4 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX94829.1 - 1.1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX94829.1 - 5e-06 26.2 0.4 5.3e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX94829.1 - 0.00062 19.7 0.1 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAX94829.1 - 0.009 15.4 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX94829.1 - 0.023 14.4 0.9 0.94 9.2 0.2 2.9 2 2 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX94829.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EAX94829.1 - 0.19 11.1 0.1 0.48 9.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein HEAT PF02985.22 EAX94830.1 - 0.015 15.5 0.0 8.6 6.9 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat HMG_box PF00505.19 EAX94831.1 - 2.4e-12 47.1 0.6 4.2e-12 46.3 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX94831.1 - 2.6e-07 31.1 0.7 4.2e-07 30.5 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 EAX94831.1 - 0.023 14.9 0.9 0.037 14.2 0.7 1.4 1 1 0 1 1 1 0 Protamine and protamine like Spo0A_C PF08769.11 EAX94831.1 - 0.048 13.7 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Baculo_PEP_C PF04513.12 EAX94832.1 - 0.002 18.2 11.0 0.072 13.1 3.0 4.0 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus NKWYS PF10364.9 EAX94832.1 - 0.0025 18.0 1.5 0.0081 16.3 1.5 2.0 1 0 0 1 1 1 1 Putative capsular polysaccharide synthesis protein CorA PF01544.18 EAX94832.1 - 0.0038 16.6 2.4 0.0038 16.6 2.4 3.1 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein p450 PF00067.22 EAX94832.1 - 0.0086 14.9 3.4 0.76 8.4 1.1 2.3 2 0 0 2 2 2 2 Cytochrome P450 COG2 PF06148.11 EAX94832.1 - 0.044 13.9 18.7 0.057 13.5 3.7 4.7 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ELYS-bb PF16687.5 EAX94832.1 - 0.061 11.9 0.6 0.12 11.0 0.6 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin RNA_pol_Rpb5_N PF03871.14 EAX94832.1 - 0.09 13.4 0.2 0.09 13.4 0.2 3.5 4 1 1 5 5 4 0 RNA polymerase Rpb5, N-terminal domain Sec3_C_2 PF15278.6 EAX94832.1 - 0.16 12.3 0.3 0.16 12.3 0.3 3.4 3 1 0 4 4 3 0 Sec3 exocyst complex subunit FdhE PF04216.12 EAX94832.1 - 0.17 11.8 4.9 0.46 10.3 3.5 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation LIAS_N PF16881.5 EAX94832.1 - 0.3 11.5 0.2 0.3 11.5 0.2 2.7 3 2 0 3 3 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family OmpH PF03938.14 EAX94832.1 - 0.43 10.9 19.3 0.44 10.9 2.1 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) MCPsignal PF00015.21 EAX94832.1 - 0.51 10.1 7.8 2.2 8.1 1.3 3.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CREPT PF16566.5 EAX94832.1 - 0.71 10.0 20.7 1.4 9.1 4.0 3.5 2 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Helo_like_N PF17111.5 EAX94832.1 - 0.95 8.8 14.5 4.9 6.5 6.9 3.9 3 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins BLOC1_2 PF10046.9 EAX94832.1 - 1 9.7 20.5 0.61 10.4 0.7 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 EAX94832.1 - 1 9.2 0.0 1 9.2 0.0 4.0 4 1 2 6 6 6 0 DASH complex subunit Dam1 Bap31_Bap29_C PF18035.1 EAX94832.1 - 1.2 9.2 14.6 0.58 10.2 0.3 4.3 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain YabA PF06156.13 EAX94832.1 - 1.6 9.4 20.4 15 6.3 1.4 4.3 2 1 1 3 3 3 0 Initiation control protein YabA ANAPC4 PF12896.7 EAX94832.1 - 1.8 8.0 8.2 0.64 9.5 0.6 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 4 NPV_P10 PF05531.12 EAX94832.1 - 2.1 8.8 28.7 0.85 10.1 2.2 5.6 3 2 3 6 6 5 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.6 EAX94832.1 - 2.8 8.0 6.2 19 5.3 0.1 3.9 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term BCNT PF07572.12 EAX94832.1 - 5.6 7.1 9.9 3 8.0 0.7 3.0 3 0 0 3 3 2 0 Bucentaur or craniofacial development Phasin PF05597.11 EAX94832.1 - 5.7 7.0 16.3 16 5.5 5.3 4.1 2 2 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RNase_J_C PF17770.1 EAX94832.1 - 6.3 7.9 8.5 12 7.1 0.1 3.9 4 0 0 4 4 3 0 Ribonuclease J C-terminal domain DUF1664 PF07889.12 EAX94832.1 - 7 6.7 25.0 0.96 9.5 4.4 4.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) FapA PF03961.13 EAX94832.1 - 7.2 5.1 17.5 0.16 10.6 3.6 3.0 2 1 1 3 3 3 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 EAX94832.1 - 8.4 6.7 22.2 0.2 11.9 3.4 4.1 2 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 EAX94832.1 - 9.6 6.5 12.4 51 4.2 2.3 4.6 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) GPS2_interact PF15784.5 EAX94835.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX94835.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX94836.1 - 0.018 15.0 9.6 0.025 14.5 9.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX94837.1 - 0.017 15.1 0.2 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX94838.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94838.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4108 PF13390.6 EAX94841.1 - 3e-58 195.8 5.5 3.3e-58 195.7 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX94841.1 - 0.097 12.9 0.1 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide IBD PF10416.9 EAX94842.1 - 1.9e-47 160.5 1.5 3.4e-47 159.6 1.5 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD TFIIA PF03153.13 EAX94842.1 - 0.24 11.4 23.8 0.29 11.1 23.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0524 PF15823.5 EAX94842.1 - 9.2 5.6 8.8 15 4.9 8.8 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 TMEM154 PF15102.6 EAX94844.1 - 0.0014 18.5 2.1 0.0014 18.5 2.1 2.0 1 1 1 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 EAX94844.1 - 0.031 14.2 1.7 0.045 13.7 1.7 1.2 1 0 0 1 1 1 0 Rifin 7TM_GPCR_Srj PF10319.9 EAX94844.1 - 0.047 13.0 1.2 0.067 12.5 1.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj Vpu PF00558.19 EAX94844.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein EssA PF10661.9 EAX94844.1 - 0.12 12.2 2.1 0.18 11.6 1.6 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Man-6-P_recep PF02157.15 EAX94844.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor MLANA PF14991.6 EAX94844.1 - 0.51 10.6 4.2 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A Sod_Fe_C PF02777.18 EAX94845.1 - 1e-32 112.3 1.8 1e-32 112.3 1.8 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAX94845.1 - 1.7e-18 66.8 0.2 1.7e-18 66.8 0.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tash_PEST PF07708.11 EAX94845.1 - 0.23 11.6 0.9 0.48 10.7 0.9 1.5 1 0 0 1 1 1 0 Tash protein PEST motif HSP70 PF00012.20 EAX94846.1 - 2.4e-190 633.7 2.0 2.8e-190 633.5 2.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX94846.1 - 1.8e-14 53.3 1.2 3.2e-13 49.2 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EAX94846.1 - 4.3e-05 22.9 0.1 0.013 14.7 0.0 3.2 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.10 EAX94846.1 - 0.0094 15.0 0.2 2.7 6.9 0.0 2.5 2 1 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EAX94846.1 - 0.047 13.2 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 EAX94846.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Snf7 PF03357.21 EAX94846.1 - 1.4 8.4 11.2 0.69 9.5 7.3 2.1 2 0 0 2 2 2 0 Snf7 BBS2_Mid PF14783.6 EAX94847.1 - 0.0065 16.5 0.1 0.11 12.5 0.0 2.5 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 EAX94847.1 - 0.014 13.9 0.3 0.016 13.7 0.3 1.1 1 0 0 1 1 1 0 Utp8 family WD40 PF00400.32 EAX94847.1 - 0.029 15.2 0.9 6.7 7.8 0.0 3.9 4 1 0 4 4 4 0 WD domain, G-beta repeat DUF3870 PF12986.7 EAX94847.1 - 0.033 14.4 0.5 0.28 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) zf-C3HC4_3 PF13920.6 EAX94848.1 - 1.6e-11 43.9 14.8 2e-11 43.6 14.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX94848.1 - 2.2e-05 24.2 14.4 3.1e-05 23.7 14.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAX94848.1 - 8.2e-05 22.9 13.4 0.00012 22.3 13.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAX94848.1 - 0.0043 17.0 13.7 0.0078 16.1 13.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 EAX94848.1 - 0.096 13.1 1.9 0.096 13.1 1.9 2.0 1 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 NitrOD1 PF18549.1 EAX94848.1 - 0.098 12.6 1.9 0.1 12.6 1.3 1.4 1 1 0 1 1 1 0 Nitrosopumilus output domain 1 DUF872 PF05915.12 EAX94849.1 - 0.02 15.1 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Colicin_V PF02674.16 EAX94849.1 - 0.072 13.1 4.4 0.089 12.8 4.4 1.1 1 0 0 1 1 1 0 Colicin V production protein DUF4939 PF16297.5 EAX94849.1 - 0.2 11.6 0.6 0.28 11.1 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) WD40 PF00400.32 EAX94850.1 - 2.5e-15 56.6 3.1 0.05 14.5 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX94850.1 - 1.7e-13 50.7 0.0 4.3e-05 23.7 0.0 5.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EAX94850.1 - 0.011 15.6 0.7 0.086 12.8 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Lipoprotein_7 PF01540.16 EAX94850.1 - 0.027 13.8 0.6 0.049 12.9 0.2 1.5 2 0 0 2 2 2 0 Adhesin lipoprotein Cytochrom_D1 PF02239.16 EAX94850.1 - 0.029 12.9 0.6 2.7 6.4 0.2 2.9 3 1 1 4 4 4 0 Cytochrome D1 heme domain BRE1 PF08647.11 EAX94850.1 - 0.044 13.8 3.0 0.096 12.8 3.0 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SUKH_6 PF14568.6 EAX94850.1 - 0.05 14.0 2.9 0.47 10.9 0.0 3.2 3 1 0 3 3 3 0 SMI1-KNR4 cell-wall DUF3748 PF12566.8 EAX94850.1 - 0.06 13.3 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) Reg_prop PF07494.11 EAX94850.1 - 0.11 12.8 0.0 8.4 7.0 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller FIVAR PF07554.13 EAX94850.1 - 0.73 10.6 3.5 1.2 10.0 2.5 1.9 1 1 1 2 2 2 0 FIVAR domain DUF1843 PF08898.10 EAX94850.1 - 1.8 9.1 3.7 1.4 9.5 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) IQ PF00612.27 EAX94851.1 - 0.00044 19.8 0.7 0.0022 17.6 0.7 2.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3447 PF11929.8 EAX94852.1 - 6e-36 122.3 7.0 6e-36 122.3 7.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94852.1 - 0.0026 18.3 0.0 0.0079 16.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX94853.1 - 5.9e-43 145.3 16.9 9.9e-17 61.3 1.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94853.1 - 6.7e-33 112.6 1.2 3.9e-14 52.8 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX94853.1 - 2.6e-31 106.7 1.7 1.6e-07 31.4 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX94853.1 - 3.2e-30 103.8 3.9 3.3e-10 40.0 0.1 3.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94853.1 - 3.1e-23 79.3 1.4 1.7e-05 24.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Stap_Strp_toxin PF01123.20 EAX94853.1 - 3.5e-07 31.0 0.9 0.022 15.6 0.1 2.5 1 1 1 2 2 2 2 Staphylococcal/Streptococcal toxin, OB-fold domain DUF348 PF03990.14 EAX94853.1 - 0.00023 20.8 0.9 8 6.3 0.0 3.8 3 1 0 3 3 3 2 G5-linked-Ubiquitin-like domain Endonuc-dimeris PF09124.10 EAX94853.1 - 0.0037 17.4 0.5 6.6 7.0 0.0 3.2 2 1 1 3 3 3 2 T4 recombination endonuclease VII, dimerisation PrmC_N PF17827.1 EAX94853.1 - 0.022 15.3 0.4 27 5.4 0.0 3.4 1 1 3 4 4 4 0 PrmC N-terminal domain Arg_repressor PF01316.21 EAX94853.1 - 0.093 12.5 0.1 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain Sec1 PF00995.23 EAX94854.1 - 6.3e-47 161.1 0.2 7.4e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Sec1 family LcnG-beta PF11632.8 EAX94854.1 - 0.037 14.0 0.7 0.085 12.8 0.7 1.6 1 0 0 1 1 1 0 Lactococcin G-beta M11L PF11099.8 EAX94854.1 - 0.077 13.3 0.1 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Apoptosis regulator M11L like DUF3456 PF11938.8 EAX94855.1 - 0.33 11.4 4.5 0.68 10.4 3.2 1.9 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP DUF5358 PF17311.2 EAX94855.1 - 0.35 10.9 9.5 0.58 10.2 8.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5358) FTA4 PF13093.6 EAX94855.1 - 4 7.3 17.6 0.077 12.9 0.8 2.3 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4107 PF13389.6 EAX94857.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX94857.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX94858.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX94859.1 - 4e-153 507.8 13.9 5.1e-153 507.5 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX94859.1 - 0.094 13.2 2.5 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX94859.1 - 0.33 11.3 3.3 14 6.1 0.0 3.3 4 0 0 4 4 4 0 Tup N-terminal Pkinase PF00069.25 EAX94863.1 - 1.2e-67 228.1 0.0 1.2e-67 228.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94863.1 - 6.3e-48 163.3 0.0 6.3e-48 163.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94863.1 - 7e-06 25.6 0.0 7e-06 25.6 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EAX94863.1 - 0.0011 17.9 0.1 0.0034 16.4 0.1 1.8 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX94863.1 - 0.098 12.6 6.7 0.13 12.1 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family His_Phos_2 PF00328.22 EAX94864.1 - 2.1e-21 76.7 0.0 2.4e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) EF-hand_1 PF00036.32 EAX94866.1 - 1.6e-06 27.2 0.1 2.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EAX94866.1 - 1.5e-05 24.5 0.1 2.7e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EAX94866.1 - 0.0013 18.1 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EAX94866.1 - 0.0021 18.5 0.1 0.0033 17.8 0.1 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EAX94866.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_9 PF14658.6 EAX94866.1 - 0.079 13.3 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Ras PF00071.22 EAX94867.1 - 9e-19 67.6 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94867.1 - 8.6e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94867.1 - 0.0063 16.0 0.0 0.0081 15.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX94867.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX94867.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAX94867.1 - 0.087 12.6 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 EAX94868.1 - 4.5e-19 68.6 0.0 5.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94868.1 - 0.0027 17.9 0.0 0.0062 16.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Cir_N PF10197.9 EAX94868.1 - 0.32 11.2 3.1 0.41 10.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR EF-hand_7 PF13499.6 EAX94869.1 - 7.3e-05 23.1 0.1 9.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EAX94869.1 - 7.8e-05 21.9 0.1 0.0052 16.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EAX94869.1 - 0.0012 18.6 0.1 0.0068 16.3 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EAX94869.1 - 0.0032 17.3 0.6 0.013 15.3 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair Trans_reg_C PF00486.28 EAX94869.1 - 0.077 13.1 0.2 0.1 12.7 0.2 1.4 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal Na_Ca_ex_C PF16494.5 EAX94869.1 - 0.093 13.2 1.4 0.1 13.1 1.4 1.1 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Raptor_N PF14538.6 EAX94870.1 - 2.1e-37 128.3 0.0 1.3e-36 125.7 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 EAX94870.1 - 1.2e-08 35.2 0.3 6.9e-08 32.8 0.1 2.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EAX94870.1 - 0.041 14.1 0.4 10 6.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EAX94870.1 - 0.19 12.3 0.4 4.8 7.8 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Aldo_ket_red PF00248.21 EAX94871.1 - 5.5e-07 29.1 0.0 5.7e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family hnRNP_Q_AcD PF18360.1 EAX94871.1 - 0.13 12.3 0.0 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TetR_C_37 PF18665.1 EAX94872.1 - 1.6 9.4 7.8 0.39 11.3 0.2 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Pro_isomerase PF00160.21 EAX94873.1 - 1.3e-23 84.0 0.0 1.5e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MIZ PF02891.20 EAX94874.1 - 9e-07 28.5 0.1 1.9e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Uds1 PF15456.6 EAX94874.1 - 0.17 12.1 0.0 17 5.6 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Mon1 PF03164.14 EAX94875.1 - 1.1e-38 133.4 0.2 1.8e-38 132.7 0.2 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 TFIID-31kDa PF02291.15 EAX94877.1 - 4.8e-08 33.1 0.2 6.1e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_M20 PF01546.28 EAX94878.1 - 9.8e-15 54.8 0.0 2e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAX94878.1 - 3.1e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Aldo_ket_red PF00248.21 EAX94879.1 - 1e-41 143.1 0.3 7.1e-41 140.3 0.3 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EAX94879.1 - 0.029 14.2 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Development and cell death domain FMN_red PF03358.15 EAX94880.1 - 1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAX94880.1 - 2.4e-08 33.9 0.0 3.7e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EAX94880.1 - 0.025 14.8 0.2 0.06 13.6 0.1 1.6 2 0 0 2 2 2 0 Flavodoxin domain TetR_C_11 PF16859.5 EAX94880.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ank_2 PF12796.7 EAX94881.1 - 2.1e-52 175.7 22.2 4.1e-16 59.3 0.3 5.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX94881.1 - 9.4e-50 165.0 3.9 5.6e-07 29.7 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX94881.1 - 1.5e-48 162.5 12.8 2.1e-11 44.1 0.3 8.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94881.1 - 1.1e-41 136.1 8.3 1.6e-05 24.9 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX94881.1 - 2.1e-32 110.8 3.7 1e-08 35.3 0.3 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94881.1 - 5.7e-17 61.5 4.2 5.7e-17 61.5 4.2 4.7 2 1 4 6 6 6 1 Domain of unknown function (DUF3447) DUF5064 PF16703.5 EAX94881.1 - 0.005 17.3 0.5 1.7 9.2 0.0 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF5064) Arg_repressor PF01316.21 EAX94881.1 - 0.0087 15.8 0.6 7.6 6.4 0.0 4.4 4 2 1 5 5 5 1 Arginine repressor, DNA binding domain CEP44 PF15007.6 EAX94881.1 - 0.085 13.0 0.3 3.7 7.7 0.0 3.1 2 1 1 3 3 3 0 Centrosomal spindle body, CEP44 DUF3447 PF11929.8 EAX94882.1 - 3.5e-11 42.9 0.3 3.5e-11 42.9 0.3 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ribosomal_S6e PF01092.19 EAX94884.1 - 1.5e-48 163.9 0.1 1.5e-48 163.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e YtzH PF14165.6 EAX94885.1 - 0.022 15.1 1.5 2.5 8.6 0.1 2.3 2 0 0 2 2 2 0 YtzH-like protein DUF3526 PF12040.8 EAX94885.1 - 0.029 14.9 0.2 0.052 14.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) BRCT PF00533.26 EAX94886.1 - 7.9e-14 51.8 5.9 2.7e-06 27.7 0.4 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAX94886.1 - 5e-10 39.7 5.2 0.088 13.2 0.1 4.5 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EAX94886.1 - 7.1e-07 29.0 2.6 0.0056 16.5 0.0 4.8 3 2 2 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EAX94886.1 - 1.2e-05 25.2 0.0 0.0074 16.2 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain LIG3_BRCT PF16759.5 EAX94886.1 - 0.17 12.2 5.3 0.49 10.7 0.5 3.8 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain zf-UBR PF02207.20 EAX94887.1 - 1.1e-13 51.1 42.6 3.5e-08 33.5 11.0 3.4 3 0 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 EAX94887.1 - 2.6 8.3 34.8 0.3 11.3 4.0 5.2 5 0 0 5 5 5 0 B-box zinc finger Hira PF07569.11 EAX94889.1 - 0.053 13.2 0.3 2.6 7.7 0.0 2.3 1 1 0 2 2 2 0 TUP1-like enhancer of split Staphostatin_A PF09022.10 EAX94889.1 - 0.059 13.3 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Staphostatin A Trypan_PARP PF05887.11 EAX94890.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2939 PF11159.8 EAX94892.1 - 0.031 14.7 0.6 0.036 14.5 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX94892.1 - 2.1 8.3 5.8 2.3 8.3 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX94893.1 - 0.013 15.5 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Transposon_TraM PF12508.8 EAX94896.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.3 1 1 0 1 1 1 0 Conjugative transposon, TraM FliJ PF02050.16 EAX94896.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.0 1 0 0 1 1 1 0 Flagellar FliJ protein Ank PF00023.30 EAX94899.1 - 1e-07 32.1 0.0 0.0037 17.6 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX94899.1 - 3.6e-07 30.6 0.0 4.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94899.1 - 9.5e-06 26.1 0.0 1.1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94899.1 - 0.00012 22.2 0.0 0.051 14.1 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat ERG2_Sigma1R PF04622.12 EAX94899.1 - 0.006 15.9 0.3 0.52 9.6 0.0 2.0 1 1 1 2 2 2 2 ERG2 and Sigma1 receptor like protein Ank_5 PF13857.6 EAX94899.1 - 0.007 16.7 0.0 0.015 15.6 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX94900.1 - 1.7e-35 120.8 4.3 1.7e-35 120.8 4.3 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX94900.1 - 5.5e-13 49.3 0.7 1.6e-08 35.0 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94900.1 - 3.5e-11 43.4 1.2 5.5e-06 26.8 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX94900.1 - 3.2e-09 36.8 0.5 1.9e-08 34.4 0.1 2.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EAX94900.1 - 6.3e-09 35.4 1.2 4.7e-06 26.5 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX94900.1 - 1.6e-05 25.1 0.1 0.0074 16.6 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Thoc2 PF11732.8 EAX94900.1 - 0.026 14.6 0.1 2 8.6 0.1 3.2 2 1 1 3 3 3 0 Transcription- and export-related complex subunit Glyco_hydro_47 PF01532.20 EAX94901.1 - 6.1e-29 101.2 2.0 2.6e-28 99.2 2.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 V-ATPase_H_N PF03224.14 EAX94902.1 - 0.037 13.3 0.0 0.099 11.9 0.0 1.7 1 0 0 1 1 1 0 V-ATPase subunit H HEAT_2 PF13646.6 EAX94902.1 - 0.041 14.3 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats NAD_Gly3P_dh_N PF01210.23 EAX94903.1 - 1.6e-40 138.6 0.0 3.5e-40 137.6 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EAX94903.1 - 1.6e-36 125.7 0.1 3.5e-36 124.6 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EAX94903.1 - 0.0049 17.4 0.1 0.091 13.4 0.1 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_16 PF00722.21 EAX94904.1 - 0.0038 16.7 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAX94904.1 - 0.1 11.0 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) RicinB_lectin_2 PF14200.6 EAX94905.1 - 0.0011 19.7 0.1 0.0099 16.6 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like TMP PF05017.14 EAX94907.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX94910.1 - 3.3e-156 517.9 13.3 4.1e-156 517.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX94910.1 - 0.035 14.4 0.8 2 8.7 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX94910.1 - 0.19 12.2 5.5 0.72 10.3 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX94910.1 - 0.19 11.6 1.3 0.6 10.0 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Tup_N PF08581.10 EAX94910.1 - 0.66 10.3 5.8 13 6.1 0.1 4.0 4 2 2 6 6 6 0 Tup N-terminal DUF2408 PF10303.9 EAX94910.1 - 1.9 9.0 6.3 0.4 11.2 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX94911.1 - 3.6e-32 110.5 0.3 8.8e-32 109.3 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF4108 PF13390.6 EAX94913.1 - 1.3e-55 187.3 4.8 1.4e-55 187.1 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RalF_SCD PF18248.1 EAX94914.1 - 0.05 13.6 0.1 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 RalF C-terminal Sec-7 capping domain COX15-CtaA PF02628.15 EAX94915.1 - 0.077 12.0 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Rad60-SLD PF11976.8 EAX94916.1 - 0.03 14.2 0.9 0.51 10.2 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Shisa PF13908.6 EAX94917.1 - 0.018 15.3 17.3 0.069 13.4 17.3 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MHC2-interact PF09307.10 EAX94917.1 - 0.033 14.2 0.4 0.048 13.7 0.4 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting SCF PF02404.15 EAX94917.1 - 0.062 12.6 0.1 0.081 12.2 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor HemX PF04375.14 EAX94917.1 - 0.093 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SARAF PF06682.12 EAX94917.1 - 0.47 10.0 15.5 0.89 9.1 15.5 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 EAX94917.1 - 2.5 9.0 4.9 0.54 11.2 0.6 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-bind_6 PF13921.6 EAX94919.1 - 2.5e-24 85.3 1.0 2.3e-14 53.4 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX94919.1 - 3.4e-21 75.2 1.1 2.1e-10 40.6 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EAX94919.1 - 7.2e-05 22.8 0.0 0.24 11.5 0.0 3.6 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain FRB_dom PF08771.11 EAX94919.1 - 0.21 12.0 2.6 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain SANT_DAMP1_like PF16282.5 EAX94919.1 - 1.7 8.9 4.3 0.66 10.2 0.3 2.4 3 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF3395 PF11875.8 EAX94919.1 - 4.3 7.2 13.7 2.6 7.9 11.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) MFS_1 PF07690.16 EAX94920.1 - 1e-33 116.8 32.1 6.9e-33 114.0 33.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 EAX94920.1 - 0.00063 19.5 2.4 0.0014 18.4 2.4 1.5 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Mx_ML PF17536.2 EAX94920.1 - 0.18 11.5 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Matrix and Matrix long proteins N-terminal Folliculin PF11704.8 EAX94922.1 - 5.1e-05 23.2 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Bromo_TP PF07524.13 EAX94922.1 - 0.057 13.4 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated CitX PF03802.14 EAX94922.1 - 0.12 12.2 0.2 0.27 11.0 0.2 1.6 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase FapA PF03961.13 EAX94922.1 - 0.21 10.1 0.5 0.31 9.6 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TBCA PF02970.16 EAX94922.1 - 0.69 10.3 3.9 1.3 9.4 2.4 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A SpoVT_C PF15714.5 EAX94923.1 - 0.055 13.5 0.4 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Stage V sporulation protein T C-terminal, transcription factor FAM184 PF15665.5 EAX94924.1 - 0.98 9.2 46.5 0.17 11.7 6.8 4.6 2 1 2 4 4 4 0 Family with sequence similarity 184, A and B DUF883 PF05957.13 EAX94924.1 - 1.8 9.2 13.4 1.1 9.9 1.0 3.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF885 PF05960.11 EAX94924.1 - 4.8 6.7 11.4 14 5.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Baculo_PEP_C PF04513.12 EAX94924.1 - 5.4 7.1 44.5 0.6 10.1 7.5 4.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EAX94924.1 - 7.2 5.9 33.4 0.68 9.2 3.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 EAX94925.1 - 5.1e-05 23.2 2.2 5.1e-05 23.2 2.2 3.1 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain ZnuA PF01297.17 EAX94925.1 - 0.015 14.8 0.6 0.015 14.8 0.6 5.2 1 1 2 5 5 5 0 Zinc-uptake complex component A periplasmic YojJ PF10372.9 EAX94925.1 - 0.026 14.6 0.8 0.026 14.6 0.8 5.5 3 2 3 7 7 7 0 Bacterial membrane-spanning protein N-terminus Baculo_PEP_C PF04513.12 EAX94925.1 - 0.12 12.4 32.4 0.79 9.8 3.8 4.7 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EAX94925.1 - 0.43 8.0 73.1 0.015 12.9 22.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ApoO PF09769.9 EAX94925.1 - 9.2 6.2 26.2 4.2 7.3 2.2 5.8 2 2 3 5 5 5 0 Apolipoprotein O DUF4838 PF16126.5 EAX94927.1 - 9.9e-86 287.4 7.0 2.1e-85 286.3 7.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) DUF4448 PF14610.6 EAX94927.1 - 0.0079 16.0 0.2 0.022 14.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EAX94927.1 - 0.012 15.5 0.4 0.012 15.5 0.4 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 EAX94927.1 - 0.015 14.8 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Orf78 PF06024.12 EAX94927.1 - 0.032 14.5 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) CD34_antigen PF06365.12 EAX94927.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 EAX94927.1 - 0.12 13.2 0.1 0.32 11.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAX94927.1 - 0.23 11.5 5.4 0.058 13.5 1.4 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 EAX94927.1 - 0.56 10.7 4.2 1.4 9.3 4.2 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LRR_5 PF13306.6 EAX94928.1 - 9.3e-142 465.3 132.5 3.1e-27 95.1 18.8 8.5 2 2 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94928.1 - 5.8e-19 67.6 24.7 0.0019 18.0 0.0 11.0 6 3 6 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 EAX94928.1 - 1.4 9.5 23.4 9 6.9 0.8 7.6 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94929.1 - 5.6e-99 327.0 70.5 3.7e-24 85.1 0.7 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94929.1 - 1.6e-16 59.8 6.1 0.0013 18.4 0.0 8.8 7 2 2 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 EAX94929.1 - 0.00092 19.6 5.6 14 6.3 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) Hepar_II_III PF07940.13 EAX94930.1 - 2e-13 50.5 0.0 2.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 EAX94930.1 - 2.9e-06 26.1 1.1 4.4e-06 25.5 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) Rsd_AlgQ PF04353.13 EAX94930.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ LRR_5 PF13306.6 EAX94931.1 - 1.7e-127 419.2 96.1 1.7e-28 99.1 0.5 7.4 2 1 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94931.1 - 1.2e-19 69.8 4.4 1.4e-05 24.7 0.1 8.3 7 2 3 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 EAX94931.1 - 2.2e-06 27.9 5.7 0.42 11.1 0.0 7.4 7 1 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94932.1 - 4.6e-104 343.4 90.5 5.2e-27 94.3 9.2 6.8 1 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94932.1 - 2.4e-13 49.6 10.1 0.0029 17.3 0.0 8.1 7 2 3 10 10 10 4 Leucine rich repeat LRR_4 PF12799.7 EAX94932.1 - 6.8e-05 23.2 15.1 0.0074 16.7 0.0 6.9 8 3 1 9 9 9 2 Leucine Rich repeats (2 copies) HCV_NS5a_C PF12941.7 EAX94932.1 - 0.42 10.4 4.6 5.5 6.8 0.3 2.3 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region DUF4108 PF13390.6 EAX94933.1 - 3.5e-53 179.4 8.1 3.9e-53 179.2 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX94934.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX94934.1 - 0.098 12.9 9.8 0.14 12.4 9.8 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX94934.1 - 7.9 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Arf PF00025.21 EAX94935.1 - 1.5e-68 229.7 0.0 1.7e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX94935.1 - 1.4e-14 53.9 0.0 1.6e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAX94935.1 - 2.3e-14 53.7 0.0 3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EAX94935.1 - 2.2e-12 46.8 0.4 2e-07 30.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EAX94935.1 - 4.7e-11 42.6 0.0 5.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAX94935.1 - 1e-09 38.1 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX94935.1 - 1.1e-08 35.1 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX94935.1 - 0.0044 16.6 0.0 0.054 13.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EAX94935.1 - 0.0075 16.7 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAX94935.1 - 0.011 15.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EAX94935.1 - 0.013 15.4 0.0 4.1 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EAX94935.1 - 0.016 15.7 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EAX94935.1 - 0.026 13.8 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TniB PF05621.11 EAX94935.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 EAX94935.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 EAX94935.1 - 0.14 11.7 0.1 0.4 10.2 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EAX94935.1 - 0.15 12.3 0.0 4.4 7.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain TMEM154 PF15102.6 EAX94937.1 - 2.9e-06 27.2 0.3 3.8e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family AJAP1_PANP_C PF15298.6 EAX94937.1 - 0.0012 19.2 2.4 0.0015 18.8 2.4 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF1180 PF06679.12 EAX94937.1 - 0.0028 18.1 0.4 0.0037 17.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) UL45 PF05473.12 EAX94937.1 - 0.023 14.3 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4366 PF14283.6 EAX94937.1 - 0.034 14.2 0.3 0.06 13.4 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Orf78 PF06024.12 EAX94937.1 - 0.056 13.7 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF5305 PF17231.2 EAX94937.1 - 0.098 12.0 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 EAX94937.1 - 0.15 12.0 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Cadherin_C_2 PF16492.5 EAX94937.1 - 0.32 11.8 1.1 1 10.2 0.8 1.9 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal Synaptobrevin PF00957.21 EAX94937.1 - 0.54 10.1 2.4 0.86 9.4 2.4 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF908 PF06012.12 EAX94937.1 - 2.9 7.2 4.7 3.4 7.0 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Shisa PF13908.6 EAX94937.1 - 7.4 6.8 9.9 0.16 12.2 0.7 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator TIG PF01833.24 EAX94938.1 - 2.2e-05 24.4 1.0 3.7e-05 23.7 1.0 1.4 1 0 0 1 1 1 1 IPT/TIG domain TIG_plexin PF17960.1 EAX94938.1 - 0.0033 17.4 0.1 0.0052 16.7 0.1 1.4 1 0 0 1 1 1 1 TIG domain DUF2034 PF10356.9 EAX94938.1 - 0.05 13.0 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Ald_Xan_dh_C2 PF02738.18 EAX94939.1 - 2.9e-186 620.2 0.0 4e-186 619.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 EAX94939.1 - 4.1e-35 120.5 0.0 1.2e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 EAX94939.1 - 8.8e-34 116.7 0.0 2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 EAX94939.1 - 1.4e-28 98.7 0.1 3e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 EAX94939.1 - 2.1e-27 95.3 0.0 5e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 EAX94939.1 - 9.3e-05 22.3 0.0 0.00027 20.8 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Crr6 PF08847.11 EAX94940.1 - 0.044 13.4 0.4 0.08 12.6 0.4 1.6 1 1 0 1 1 1 0 Chlororespiratory reduction 6 PCRF PF03462.18 EAX94940.1 - 0.1 12.5 2.4 0.13 12.1 2.4 1.1 1 0 0 1 1 1 0 PCRF domain DUF5446 PF17522.2 EAX94940.1 - 0.33 11.1 4.3 0.54 10.5 4.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5446) Methyltransf_25 PF13649.6 EAX94941.1 - 4.6e-10 40.1 0.0 8.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAX94941.1 - 1.2e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EAX94941.1 - 1.1e-07 32.4 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX94941.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAX94941.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 EAX94941.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 EAX94941.1 - 7e-05 22.7 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAX94941.1 - 7.7e-05 22.2 0.1 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EAX94941.1 - 0.00082 19.3 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX94941.1 - 0.0026 18.5 0.0 0.0048 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAX94941.1 - 0.0067 15.4 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EAX94941.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 EAX94941.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 EAX94941.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RRM_1 PF00076.22 EAX94942.1 - 0.00049 19.9 1.0 0.0017 18.2 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_II PF06009.12 EAX94942.1 - 0.0027 17.7 9.0 0.0027 17.7 9.0 2.1 1 1 1 2 2 2 1 Laminin Domain II Nup35_RRM_2 PF14605.6 EAX94942.1 - 0.025 14.6 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA_23 PF13476.6 EAX94942.1 - 0.17 12.4 15.5 0.2 12.1 15.5 1.3 1 0 0 1 1 1 0 AAA domain DUF3037 PF11236.8 EAX94942.1 - 0.24 11.8 3.6 0.22 11.9 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Phage_TAC_3 PF06896.11 EAX94942.1 - 1.8 9.2 15.5 1.6 9.3 10.1 2.3 1 1 1 2 2 2 0 Phage tail assembly chaperone proteins, TAC Ribosomal_L29 PF00831.23 EAX94942.1 - 5.8 7.0 13.0 5.3 7.1 1.8 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein LRR_5 PF13306.6 EAX94944.1 - 1.4e-06 28.3 7.3 6.1e-05 23.0 2.2 2.8 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF4508 PF14969.6 EAX94945.1 - 0.0026 18.0 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Tfb4 PF03850.14 EAX94945.1 - 0.045 13.2 2.2 0.093 12.2 2.2 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 SPACA9 PF15120.6 EAX94945.1 - 0.058 13.2 2.1 0.16 11.7 2.1 1.7 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 FlaF PF07309.11 EAX94945.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF Bromodomain PF00439.25 EAX94946.1 - 6.3e-07 29.4 0.2 1.9e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_19 PF18015.1 EAX94946.1 - 0.018 15.2 0.7 0.053 13.7 0.2 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ACDC PF14733.6 EAX94946.1 - 0.054 13.8 2.2 5.4 7.4 0.1 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal DUF5365 PF17326.2 EAX94947.1 - 0.023 15.1 0.1 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5365) FAR1 PF03101.15 EAX94948.1 - 0.046 14.4 0.2 0.13 13.0 0.2 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF4107 PF13389.6 EAX94950.1 - 1.8e-65 220.1 13.4 2e-63 213.4 13.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX94950.1 - 0.091 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta YopE_N PF09020.10 EAX94953.1 - 0.029 14.6 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 YopE, N terminal Bromo_TP_like PF17027.5 EAX94953.1 - 0.098 12.8 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Histone-fold protein LigB PF02900.18 EAX94954.1 - 1.3e-28 99.9 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase SNARE PF05739.19 EAX94955.1 - 2.9e-10 40.0 1.2 9.9e-10 38.3 1.2 2.0 1 0 0 1 1 1 1 SNARE domain LAP1C PF05609.12 EAX94955.1 - 0.0012 18.1 7.4 0.0014 17.8 7.4 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) CLZ PF16526.5 EAX94955.1 - 0.015 15.6 4.4 0.92 9.9 0.0 3.4 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LMBR1 PF04791.16 EAX94955.1 - 0.02 13.8 5.3 0.03 13.2 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptobrevin PF00957.21 EAX94955.1 - 0.021 14.6 3.6 0.021 14.6 3.6 2.3 2 0 0 2 2 2 0 Synaptobrevin PBP1_TM PF14812.6 EAX94955.1 - 0.031 14.6 3.2 0.46 10.9 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UL45 PF05473.12 EAX94955.1 - 0.034 13.8 0.2 0.1 12.2 0.0 1.8 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Striatin PF08232.12 EAX94955.1 - 0.042 14.4 6.4 0.08 13.5 6.4 1.5 1 0 0 1 1 1 0 Striatin family Protocadherin PF08374.11 EAX94955.1 - 0.05 13.6 0.6 0.05 13.6 0.6 2.3 1 1 1 3 3 3 0 Protocadherin DUF4064 PF13273.6 EAX94955.1 - 0.069 13.4 1.4 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Hrs_helical PF12210.8 EAX94955.1 - 0.48 11.0 14.4 0.045 14.3 3.6 2.5 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Orf78 PF06024.12 EAX94955.1 - 0.88 9.9 9.7 20 5.5 9.7 2.6 1 1 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 EAX94955.1 - 1.2 7.9 4.5 3.6 6.2 4.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sulfatase_C PF14707.6 EAX94955.1 - 2.1 9.1 7.9 11 6.8 0.5 2.7 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase ING PF12998.7 EAX94955.1 - 2.7 8.6 14.1 0.23 12.0 2.9 2.7 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Shisa PF13908.6 EAX94955.1 - 5 7.3 5.5 1.8 8.8 0.7 2.2 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF745 PF05335.13 EAX94955.1 - 6.5 6.4 17.1 14 5.4 13.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) eIF3_N PF09440.10 EAX94955.1 - 7.4 7.0 12.5 1.3 9.5 3.4 2.4 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain BRE1 PF08647.11 EAX94955.1 - 8.5 6.5 20.2 0.064 13.3 5.1 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Ank_2 PF12796.7 EAX94956.1 - 3e-24 85.4 0.2 1.1e-12 48.4 0.0 4.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94956.1 - 1.5e-22 79.7 0.3 1.2e-07 32.2 0.0 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX94956.1 - 4.2e-20 71.2 0.7 2e-06 28.0 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX94956.1 - 2.1e-19 69.3 0.0 2.6e-09 37.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94956.1 - 5.6e-17 60.1 1.2 0.0009 19.5 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 EAX94956.1 - 1.6e-11 44.0 3.3 3.4e-08 33.3 0.6 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) UQ_con PF00179.26 EAX94957.1 - 2.4e-06 27.2 0.1 3.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rota_NS6 PF04866.12 EAX94957.1 - 0.064 13.5 0.1 0.099 12.9 0.1 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 Pkinase_Tyr PF07714.17 EAX94958.1 - 1.3e-51 175.4 0.0 1.9e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX94958.1 - 1e-50 172.6 0.0 2.4e-50 171.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ank_5 PF13857.6 EAX94958.1 - 1.5e-16 60.2 0.0 0.00017 21.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94958.1 - 6.1e-14 52.4 0.2 3e-08 34.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX94958.1 - 1.8e-11 43.2 0.6 0.00043 20.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX94958.1 - 1e-08 35.5 0.1 0.00041 20.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX94958.1 - 1.3e-06 28.6 0.2 0.00089 19.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Kdo PF06293.14 EAX94958.1 - 0.0021 17.5 0.4 0.0048 16.3 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX94958.1 - 0.0097 14.7 0.1 0.024 13.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EAX94958.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EAX94958.1 - 0.24 11.3 0.1 0.44 10.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5383 PF17355.2 EAX94959.1 - 0.012 15.9 0.5 0.014 15.8 0.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Peptidase_M61_N PF17899.1 EAX94960.1 - 0.066 13.3 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain P21-Arc PF04062.14 EAX94961.1 - 9.5e-40 136.5 0.1 1.1e-39 136.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNOT11 PF10155.9 EAX94962.1 - 0.00018 21.6 3.9 0.00069 19.8 0.5 2.4 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 11 SapB_1 PF05184.15 EAX94965.1 - 2.6 8.1 4.3 2.8 8.0 0.2 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 START PF01852.19 EAX94966.1 - 2.7e-12 46.6 0.0 2.1e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 START domain ArsD PF06953.11 EAX94966.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD Ras PF00071.22 EAX94967.1 - 9.4e-55 184.6 0.0 1.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94967.1 - 2.4e-32 111.7 0.1 6.4e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94967.1 - 1.4e-15 57.2 0.0 1.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX94967.1 - 1.1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX94967.1 - 4.3e-06 26.8 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX94967.1 - 9.8e-06 25.1 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EAX94967.1 - 0.00095 19.0 0.2 0.069 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 EAX94967.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EAX94967.1 - 0.0027 17.3 0.4 0.15 11.6 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX94967.1 - 0.0039 17.1 0.7 0.073 13.0 0.3 2.6 1 1 1 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EAX94967.1 - 0.032 14.0 0.0 0.078 12.7 0.0 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EAX94967.1 - 0.042 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EAX94967.1 - 0.054 13.8 0.1 0.096 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX94967.1 - 0.066 13.6 0.5 0.17 12.3 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EAX94967.1 - 0.1 12.2 1.0 0.76 9.3 0.1 2.5 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EAX94967.1 - 0.11 13.0 0.1 0.27 11.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAX94967.1 - 0.13 12.7 0.2 0.34 11.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter DDR PF08841.10 EAX94969.1 - 0.17 10.9 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX94970.1 - 0.3 11.1 8.0 0.32 11.0 8.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX94970.1 - 7.7 7.0 6.7 8.3 6.9 6.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TALPID3 PF15324.6 EAX94970.1 - 9.6 3.7 14.3 11 3.6 14.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Como_SCP PF02248.16 EAX94971.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Small coat protein FAS_N PF17828.1 EAX94972.1 - 0.016 15.2 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX94972.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal PRA-PH PF01503.17 EAX94973.1 - 0.63 10.5 4.1 10 6.6 3.5 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4625 PF15418.6 EAX94975.1 - 3.8e-12 46.6 34.1 0.071 13.3 0.3 12.3 6 4 4 10 10 10 5 Domain of unknown function (DUF4625) Big_7 PF17957.1 EAX94975.1 - 9.6e-11 42.3 29.5 0.046 14.5 0.0 10.6 9 4 2 11 11 11 5 Bacterial Ig domain Alph_Pro_TM PF09608.10 EAX94975.1 - 2.4e-06 27.5 0.5 2 8.2 0.0 5.4 5 1 0 5 5 5 2 Putative transmembrane protein (Alph_Pro_TM) DUF4832 PF16116.5 EAX94975.1 - 0.0063 16.4 0.9 7.2 6.4 0.0 5.0 7 0 0 7 7 7 1 Domain of unknown function (DUF4832) Big_3_3 PF13750.6 EAX94975.1 - 0.0089 15.7 19.5 0.89 9.2 1.1 8.0 10 1 0 10 10 10 2 Bacterial Ig-like domain (group 3) DOPA_dioxygen PF08883.11 EAX94975.1 - 0.098 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family MG2 PF01835.19 EAX94975.1 - 0.12 12.8 0.2 93 3.6 0.0 4.8 6 0 0 6 6 6 0 MG2 domain Nitroreductase PF00881.24 EAX94976.1 - 6.4e-28 97.9 0.0 7.2e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX94976.1 - 0.00079 19.1 0.1 0.13 11.8 0.0 2.6 1 1 1 2 2 2 2 Putative TM nitroreductase Ank_2 PF12796.7 EAX94979.1 - 1.7e-34 118.3 2.5 9.8e-15 54.9 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94979.1 - 3.7e-33 113.5 3.9 2.2e-09 37.7 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX94979.1 - 2.3e-30 104.3 0.4 3.5e-07 30.4 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94979.1 - 1.7e-26 89.3 1.8 3.2e-05 24.0 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX94979.1 - 6.2e-23 80.2 4.1 0.00025 21.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 EAX94979.1 - 0.0045 16.9 1.7 1.6 8.7 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Pro_CA PF00484.19 EAX94979.1 - 0.046 14.0 0.1 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 Carbonic anhydrase Pkinase PF00069.25 EAX94980.1 - 1.5e-43 149.0 0.0 4.4e-43 147.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX94980.1 - 2.7e-26 92.4 0.0 7e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX94980.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.22 EAX94980.1 - 0.11 12.8 0.0 11 6.6 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat 4HBT PF03061.22 EAX94981.1 - 7.3e-08 32.7 0.0 9.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EAX94981.1 - 0.096 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Ras PF00071.22 EAX94982.1 - 7.8e-33 113.4 0.1 1e-32 113.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX94982.1 - 9.1e-28 96.9 0.0 1.5e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX94982.1 - 2e-08 33.9 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX94982.1 - 1.7e-07 30.9 0.0 2.4e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX94982.1 - 2.7e-06 27.2 0.0 9.1e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EAX94982.1 - 2e-05 24.6 0.0 4.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EAX94982.1 - 2.4e-05 23.8 0.0 0.04 13.2 0.0 2.2 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 EAX94982.1 - 5.9e-05 23.0 0.0 0.13 12.2 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EAX94982.1 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAX94982.1 - 0.0011 18.5 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAX94982.1 - 0.0069 16.8 0.0 0.01 16.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DoxA PF07680.11 EAX94982.1 - 0.024 14.5 0.0 0.06 13.3 0.0 1.6 2 0 0 2 2 2 0 TQO small subunit DoxA AAA_7 PF12775.7 EAX94982.1 - 0.034 13.7 0.1 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX94982.1 - 0.058 13.1 0.2 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAX94982.1 - 0.076 13.0 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EAX94982.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 EAX94982.1 - 0.17 11.7 0.1 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RabGAP-TBC PF00566.18 EAX94983.1 - 2.3e-48 164.7 10.0 3.1e-48 164.3 10.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5601 PF18151.1 EAX94983.1 - 0.071 13.4 0.3 0.27 11.6 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Sec23_trunk PF04811.15 EAX94985.1 - 2.9e-14 53.2 0.0 2.1e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAX94985.1 - 1.7e-10 41.5 1.4 1.4e-09 38.5 0.0 2.8 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain DUF678 PF05077.12 EAX94985.1 - 0.078 13.1 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) LRR_5 PF13306.6 EAX94986.1 - 1.9e-192 629.2 148.2 1.8e-29 102.3 3.8 8.2 3 3 5 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94986.1 - 2.9e-23 81.4 10.0 0.0069 16.1 0.4 10.4 6 4 6 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 EAX94986.1 - 0.059 13.8 25.6 4.6 7.8 0.1 9.6 6 4 4 12 12 12 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX94987.1 - 1.1e-08 35.1 0.1 1.3e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX94987.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 2 1 0 2 2 2 0 Leucine rich repeat Ank_2 PF12796.7 EAX94988.1 - 9.2e-110 359.4 58.3 5.8e-20 71.7 1.9 9.9 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX94988.1 - 5.1e-101 329.8 37.9 2.5e-12 47.0 0.1 15.8 2 2 15 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 EAX94988.1 - 2.5e-94 305.9 47.0 8.1e-08 32.4 0.2 17.8 18 0 0 18 18 18 17 Ankyrin repeat Ank_5 PF13857.6 EAX94988.1 - 6.1e-85 278.2 34.9 5.5e-10 39.3 0.1 13.1 6 5 8 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX94988.1 - 1.8e-79 252.1 37.1 2.2e-05 24.5 0.0 17.9 18 1 0 18 18 18 15 Ankyrin repeat Ribosomal_S6 PF01250.17 EAX94988.1 - 0.0049 17.1 0.6 9.5 6.6 0.0 4.9 5 2 2 7 7 7 1 Ribosomal protein S6 EutK_C PF16365.5 EAX94988.1 - 0.025 14.6 0.0 0.88 9.6 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilization protein EutK C-terminus CEP44 PF15007.6 EAX94988.1 - 0.059 13.5 1.3 97 3.1 0.0 5.3 5 2 2 7 7 7 0 Centrosomal spindle body, CEP44 CCDC84 PF14968.6 EAX94988.1 - 1.6 8.3 5.9 4.7 6.7 0.1 3.4 2 1 0 3 3 3 0 Coiled coil protein 84 PH_8 PF15409.6 EAX94988.1 - 2 8.7 7.1 52 4.2 0.0 5.9 5 4 5 10 10 10 0 Pleckstrin homology domain DUF3447 PF11929.8 EAX94989.1 - 1e-20 73.5 10.6 1.1e-20 73.3 5.6 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX94989.1 - 8.2e-14 51.8 0.6 5.3e-07 30.1 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX94989.1 - 1.7e-11 44.5 0.1 3.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX94989.1 - 5.1e-09 36.2 0.0 9e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX94989.1 - 2.5e-08 34.0 1.7 1.6e-06 28.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX94989.1 - 4e-08 32.9 2.6 1.3e-05 25.2 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat ATG16 PF08614.11 EAX94990.1 - 0.00056 20.2 29.6 0.00056 20.2 29.6 5.2 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) GPS2_interact PF15784.5 EAX94990.1 - 0.0028 18.1 9.2 0.0028 18.1 9.2 6.9 4 3 4 8 8 8 1 G-protein pathway suppressor 2-interacting domain Spc7 PF08317.11 EAX94990.1 - 2.4 6.9 114.8 0.03 13.2 24.8 5.9 1 1 4 6 6 6 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAX94990.1 - 4.3 4.7 94.4 0.021 12.4 66.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Aldo_ket_red PF00248.21 EAX94991.1 - 3.2e-19 69.2 0.0 2.4e-18 66.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4840 PF16128.5 EAX94991.1 - 0.13 12.3 0.1 6.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4840) DUF4107 PF13389.6 EAX94993.1 - 1.9e-71 239.5 2.7 2.5e-71 239.1 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PTR PF12789.7 EAX94995.1 - 4.6e-11 42.6 35.1 4.8e-08 32.9 5.6 5.6 5 1 0 5 5 5 3 Phage tail repeat like Collagen PF01391.18 EAX94995.1 - 3.1e-07 30.0 13.5 5.9e-07 29.2 13.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX94995.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus RecG_N PF17190.4 EAX94995.1 - 0.19 12.5 3.2 52 4.7 0.0 4.3 4 0 0 4 4 4 0 RecG N-terminal helical domain AATF-Che1 PF13339.6 EAX94995.1 - 1.7 9.3 5.8 41 4.9 2.3 3.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DNA_pol_B_2 PF03175.13 EAX94996.1 - 2.5e-29 102.5 6.4 4.1e-29 101.8 6.4 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX94996.1 - 0.032 14.5 0.1 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) JMY PF15871.5 EAX94996.1 - 0.035 13.4 0.5 0.054 12.8 0.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Trypan_PARP PF05887.11 EAX94997.1 - 0.077 13.0 10.9 0.12 12.3 10.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX94998.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain NIF PF03031.18 EAX94999.1 - 1.1e-40 138.9 0.1 1.4e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ricin_B_lectin PF00652.22 EAX95000.1 - 7.8e-13 48.8 0.1 1.6e-06 28.4 0.0 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAX95000.1 - 2.5e-06 28.1 0.2 0.0038 17.9 0.2 2.4 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like TPR_MLP1_2 PF07926.12 EAX95001.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX95001.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX95001.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family E1-E2_ATPase PF00122.20 EAX95004.1 - 9.2e-56 188.2 1.5 9.2e-56 188.2 1.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAX95004.1 - 7.5e-33 113.8 0.1 7.5e-33 113.8 0.1 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAX95004.1 - 1.4e-21 77.7 0.5 1.4e-21 77.7 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAX95004.1 - 1.6e-21 75.8 0.5 9.6e-21 73.3 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAX95004.1 - 2.1e-21 75.8 0.0 5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 EAX95004.1 - 0.0094 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAX95004.1 - 0.029 14.1 0.2 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TrbC PF04956.13 EAX95004.1 - 9.2 6.6 19.9 1.2 9.4 0.3 3.9 4 0 0 4 4 4 0 TrbC/VIRB2 family Transposase_20 PF02371.16 EAX95005.1 - 6.9e-19 68.0 0.0 3.1e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family HHH_3 PF12836.7 EAX95005.1 - 0.05 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif GntR PF00392.21 EAX95006.1 - 2.8e-13 49.3 0.1 6.3e-13 48.2 0.0 1.6 2 1 0 2 2 2 1 Bacterial regulatory proteins, gntR family RPA_C PF08784.11 EAX95006.1 - 0.0028 18.3 0.1 0.0078 16.9 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal HTH_36 PF13730.6 EAX95006.1 - 0.0047 16.8 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Porphobil_deam PF01379.20 EAX95006.1 - 0.079 12.5 0.1 0.31 10.5 0.0 1.8 1 1 1 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain HTH_24 PF13412.6 EAX95006.1 - 0.12 12.0 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PRR18 PF15671.5 EAX95006.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 AAA_21 PF13304.6 EAX95007.1 - 2.2e-06 27.7 0.6 3.3e-06 27.1 0.1 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EAX95007.1 - 1.9e-05 25.2 0.0 4.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Xan_ur_permease PF00860.20 EAX95008.1 - 1.3e-30 106.4 29.8 1.9e-30 105.9 29.8 1.1 1 0 0 1 1 1 1 Permease family SLH PF00395.20 EAX95010.1 - 2.7e-40 136.1 4.2 4.4e-16 58.6 0.2 4.3 4 0 0 4 4 4 4 S-layer homology domain tRNA-synt_1c PF00749.21 EAX95011.1 - 2e-111 371.8 0.0 3.3e-111 371.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DDE_Tnp_ISL3 PF01610.17 EAX95012.1 - 3.3e-68 230.0 1.6 4.4e-68 229.6 1.6 1.2 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 EAX95012.1 - 1.4e-10 41.6 9.2 4e-10 40.2 9.2 1.8 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 EAX95012.1 - 2.3e-05 23.7 0.0 6.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EAX95012.1 - 0.00023 20.8 0.2 0.00095 18.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 EAX95012.1 - 0.00033 20.7 0.3 0.0011 19.0 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Lar_restr_allev PF14354.6 EAX95012.1 - 0.0052 17.1 1.6 0.011 16.1 1.6 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar Transposase_mut PF00872.18 EAX95012.1 - 0.0054 15.6 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family CxC3 PF18804.1 EAX95012.1 - 0.02 14.7 1.5 0.049 13.5 1.5 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases PRANC PF09372.10 EAX95012.1 - 0.055 13.8 9.1 0.74 10.2 1.7 3.5 3 1 0 3 3 3 0 PRANC domain HTH_36 PF13730.6 EAX95012.1 - 0.085 12.8 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Zn-ribbon_8 PF09723.10 EAX95012.1 - 0.32 11.2 5.8 5.8 7.1 1.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EAX95012.1 - 1.1 9.3 9.7 5.2 7.1 9.7 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ogr_Delta PF04606.12 EAX95012.1 - 1.3 9.1 5.0 5.5 7.1 0.2 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger NapB PF03892.14 EAX95012.1 - 3 7.9 5.0 7.9 6.5 5.0 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Polysacc_deac_1 PF01522.21 EAX95013.1 - 8.9e-27 93.4 0.3 1.7e-26 92.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DHHA1 PF02272.19 EAX95013.1 - 0.023 15.1 0.7 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 DHHA1 domain Sigma_reg_N PF13800.6 EAX95013.1 - 0.082 13.2 0.9 0.22 11.8 0.9 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2116 PF09889.9 EAX95013.1 - 0.85 9.6 2.5 1.6 8.7 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FtsH_ext PF06480.15 EAX95013.1 - 3.7 7.9 5.8 4.8 7.6 2.2 2.8 3 1 0 3 3 3 0 FtsH Extracellular SNARE PF05739.19 EAX95013.1 - 3.8 7.6 8.7 19 5.4 3.4 3.3 3 0 0 3 3 3 0 SNARE domain DUF1858 PF08984.11 EAX95014.1 - 2.6e-22 78.7 0.6 3e-22 78.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1858) ScdA_N PF04405.14 EAX95014.1 - 0.005 16.5 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown function (DUF542) Cu_amine_oxidN1 PF07833.11 EAX95015.1 - 0.00012 22.4 0.4 0.0047 17.4 0.1 2.2 1 1 1 2 2 2 2 Copper amine oxidase N-terminal domain Mem_trans PF03547.18 EAX95016.1 - 1.5e-20 73.0 22.7 3.4e-13 48.8 8.3 2.0 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.16 EAX95016.1 - 0.0013 18.4 3.1 0.0013 18.4 3.1 3.1 2 1 1 3 3 3 1 Sodium Bile acid symporter family TMEM156 PF15106.6 EAX95016.1 - 0.018 14.5 1.3 0.038 13.4 1.3 1.5 1 0 0 1 1 1 0 TMEM156 protein family DUF1240 PF06836.12 EAX95016.1 - 3 8.5 23.0 6.5 7.4 1.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1240) Caveolin PF01146.17 EAX95016.1 - 3.1 7.8 18.5 0.033 14.2 3.0 3.1 2 1 0 3 3 3 0 Caveolin S-AdoMet_synt_C PF02773.16 EAX95017.1 - 1.8e-67 225.6 0.0 3.1e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAX95017.1 - 1.4e-49 167.3 0.0 3.8e-49 165.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAX95017.1 - 5.1e-42 142.6 0.7 9e-42 141.8 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Bac_DNA_binding PF00216.21 EAX95021.1 - 4.6e-34 116.5 0.6 5e-34 116.4 0.6 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EAX95021.1 - 1.1e-08 35.1 0.1 1.3e-08 34.9 0.1 1.2 1 1 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EAX95021.1 - 6.6e-07 29.1 0.0 9.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 EAX95021.1 - 7.6e-05 22.8 0.1 0.00011 22.3 0.1 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EAX95021.1 - 0.0088 16.2 0.0 0.0094 16.1 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-DNA_bdg PF14848.6 EAX95021.1 - 0.035 14.1 0.1 0.062 13.3 0.1 1.6 1 1 0 1 1 1 0 DNA-binding domain S1 PF00575.23 EAX95022.1 - 1.5e-21 76.5 2.9 2.4e-21 75.9 2.9 1.3 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 EAX95022.1 - 0.0011 19.0 0.5 0.014 15.4 0.3 2.5 1 1 1 2 2 2 1 S1 domain CFAP91 PF14738.6 EAX95022.1 - 0.026 14.6 3.0 0.031 14.3 3.0 1.2 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 PCB_OB PF17092.5 EAX95022.1 - 0.058 14.1 0.3 0.14 12.9 0.2 1.9 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain DUF3069 PF11269.8 EAX95022.1 - 0.22 11.8 4.0 0.38 11.0 3.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3069) ATP_bind_3 PF01171.20 EAX95023.1 - 2.2e-50 170.9 0.1 6.9e-50 169.3 0.1 1.8 2 1 0 2 2 2 1 PP-loop family TilS_C PF11734.8 EAX95023.1 - 2.6e-14 52.4 0.0 5.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 TilS substrate C-terminal domain B3_4 PF03483.17 EAX95023.1 - 1.7e-07 31.0 0.1 3.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain GUN4_N PF16416.5 EAX95023.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal DUF1870 PF08965.10 EAX95023.1 - 0.2 11.7 0.6 1 9.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Pribosyltran PF00156.27 EAX95024.1 - 2e-17 63.2 0.1 2.2e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAX95024.1 - 0.0069 15.9 0.0 0.0082 15.6 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Peptidase_M41 PF01434.18 EAX95025.1 - 1.4e-69 233.8 0.2 2.5e-69 233.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAX95025.1 - 5.7e-44 149.7 0.0 1.6e-43 148.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAX95025.1 - 3.1e-14 52.5 0.4 1e-13 50.9 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EAX95025.1 - 6.7e-06 26.1 0.4 9.3e-05 22.4 0.0 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAX95025.1 - 0.00018 21.3 0.0 0.00059 19.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EAX95025.1 - 0.00019 20.8 0.3 0.00061 19.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EAX95025.1 - 0.00052 20.4 0.2 0.027 14.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EAX95025.1 - 0.0026 17.9 0.0 0.0066 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX95025.1 - 0.004 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TetR_C_36 PF18598.1 EAX95025.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 EAX95025.1 - 0.0069 16.7 0.6 0.34 11.2 0.1 2.7 2 1 0 3 3 3 1 AAA domain AAA_2 PF07724.14 EAX95025.1 - 0.012 15.7 0.1 0.065 13.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EAX95025.1 - 0.023 15.3 0.9 0.13 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAX95025.1 - 0.025 14.3 0.2 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAX95025.1 - 0.04 13.4 0.2 0.18 11.3 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EAX95025.1 - 0.056 12.7 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 EAX95025.1 - 0.062 13.3 0.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAX95025.1 - 0.078 13.2 0.1 0.22 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EAX95025.1 - 0.084 12.3 0.2 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EAX95025.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EAX95025.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EAX95025.1 - 0.13 12.7 2.2 0.24 11.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 EAX95025.1 - 0.15 12.1 0.0 0.49 10.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Transpeptidase PF00905.22 EAX95026.1 - 6e-35 120.9 4.4 6e-35 120.9 4.4 2.2 2 1 0 2 2 2 1 Penicillin binding protein transpeptidase domain Transgly PF00912.22 EAX95026.1 - 4.9e-28 97.8 0.4 1.2e-27 96.5 0.1 1.9 2 0 0 2 2 2 1 Transglycosylase SHOCT PF09851.9 EAX95026.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Short C-terminal domain CDC45 PF02724.14 EAX95026.1 - 0.2 9.9 8.4 0.35 9.1 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EAX95026.1 - 2.7 8.4 6.9 7.3 7.0 6.9 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 EAX95026.1 - 4.6 6.4 5.6 7.1 5.8 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BioY PF02632.14 EAX95027.1 - 7e-29 100.6 17.6 7.8e-29 100.5 17.6 1.0 1 0 0 1 1 1 1 BioY family Pan_kinase PF03309.14 EAX95028.1 - 9.1e-38 130.2 0.0 1.1e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Type III pantothenate kinase Dus PF01207.17 EAX95029.1 - 7.8e-84 281.4 0.0 8.5e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EAX95029.1 - 8.9e-05 21.8 7.2 0.0049 16.1 0.0 3.3 1 1 2 3 3 3 2 Dihydroorotate dehydrogenase NanE PF04131.14 EAX95029.1 - 0.00048 19.4 0.1 0.00088 18.5 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EAX95029.1 - 0.0043 16.6 0.2 0.74 9.2 0.0 2.4 2 0 0 2 2 2 2 Histidine biosynthesis protein Oxidored_FMN PF00724.20 EAX95029.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.17 EAX95029.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 Thiamine monophosphate synthase GreA_GreB_N PF03449.15 EAX95030.1 - 3.8e-28 97.5 3.1 6.1e-28 96.8 3.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 EAX95030.1 - 2.5e-21 75.3 0.9 4.8e-21 74.5 0.9 1.4 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Ribosomal_S25 PF03297.15 EAX95030.1 - 0.026 14.7 2.7 0.05 13.8 0.1 2.0 1 1 1 2 2 2 0 S25 ribosomal protein Cation_ATPase_C PF00689.21 EAX95031.1 - 2.7e-42 144.5 12.9 2.7e-42 144.5 12.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EAX95031.1 - 4e-29 101.4 1.2 8e-29 100.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAX95031.1 - 2.6e-21 75.5 0.0 7.1e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAX95031.1 - 1.6e-16 61.2 0.0 1.1e-15 58.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAX95031.1 - 1.5e-09 37.4 0.0 3.7e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAX95031.1 - 1.7e-05 24.7 0.5 0.0035 17.1 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ADP_ribosyl_GH PF03747.14 EAX95032.1 - 5.9e-38 131.3 0.0 7.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_4 PF12799.7 EAX95032.1 - 3.9e-09 36.6 1.6 0.0052 17.2 0.4 4.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF2939 PF11159.8 EAX95033.1 - 2.6 8.5 18.3 74 3.9 0.0 7.7 5 2 2 8 8 8 0 Protein of unknown function (DUF2939) Vma12 PF11712.8 EAX95034.1 - 0.04 14.0 0.3 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4635 PF15466.6 EAX95035.1 - 0.0059 16.1 0.8 0.016 14.7 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) DUF1539 PF07560.11 EAX95035.1 - 0.011 15.9 3.9 0.011 15.9 3.9 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF2960 PF11173.8 EAX95035.1 - 0.013 15.9 0.9 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) UVR PF02151.19 EAX95035.1 - 0.017 14.9 1.1 0.017 14.9 1.1 4.6 6 0 0 6 6 6 0 UvrB/uvrC motif UPF0767 PF15990.5 EAX95035.1 - 1.9 8.7 8.1 0.25 11.5 0.5 3.1 2 1 1 3 3 3 0 UPF0767 family Ras PF00071.22 EAX95036.1 - 8.9e-42 142.4 0.0 1e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95036.1 - 4.4e-29 101.1 0.0 8e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95036.1 - 2.2e-14 53.3 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX95036.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX95036.1 - 0.00033 20.6 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX95036.1 - 0.00059 19.4 0.0 0.0039 16.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX95036.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAX95036.1 - 0.0023 17.4 0.1 0.49 9.9 0.0 2.6 1 1 1 3 3 3 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EAX95036.1 - 0.0025 17.6 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EAX95036.1 - 0.0082 16.0 0.3 0.073 12.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EAX95036.1 - 0.0085 16.1 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_7 PF12775.7 EAX95036.1 - 0.0096 15.4 0.1 0.058 12.9 0.0 2.2 2 1 1 3 3 3 1 P-loop containing dynein motor region AAA PF00004.29 EAX95036.1 - 0.041 14.3 0.0 0.096 13.1 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EAX95036.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L44 PF00935.19 EAX95037.1 - 7.1e-25 87.3 9.9 7.1e-25 87.3 9.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Rpr2 PF04032.16 EAX95037.1 - 0.11 12.8 6.1 0.32 11.3 6.1 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 EAX95037.1 - 0.12 12.9 13.7 2 9.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 EAX95037.1 - 1.1 9.6 9.1 0.23 11.7 1.3 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.11 EAX95037.1 - 1.1 9.5 10.7 0.1 12.8 1.6 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.13 EAX95037.1 - 2.3 8.3 15.9 3.6 7.7 1.6 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like TENA_THI-4 PF03070.16 EAX95038.1 - 0.041 13.7 0.4 0.072 12.9 0.4 1.4 1 1 0 1 1 1 0 TENA/THI-4/PQQC family CCDC24 PF15669.5 EAX95038.1 - 0.96 9.3 7.3 11 5.8 0.3 3.0 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 24 family DUF563 PF04577.14 EAX95039.1 - 7.6e-06 26.2 0.0 2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) PMSR PF01625.21 EAX95040.1 - 9.8e-60 201.2 2.0 1.1e-59 201.0 2.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.25 EAX95041.1 - 1.6e-28 99.9 0.5 1.6e-28 99.9 0.5 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95041.1 - 3.8e-28 98.5 0.2 9.4e-28 97.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 EAX95041.1 - 0.0026 17.5 2.7 0.22 11.1 0.6 2.9 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Ank_2 PF12796.7 EAX95042.1 - 7.2e-52 173.9 9.6 8.2e-20 71.2 0.2 3.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95042.1 - 1.2e-26 91.9 0.6 3.9e-05 23.9 0.0 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX95042.1 - 1.3e-26 92.3 0.5 1.6e-07 31.4 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95042.1 - 3e-19 69.1 0.0 1.2e-08 35.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95042.1 - 1.6e-17 61.8 0.3 0.013 15.9 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Adenine_glyco PF03352.13 EAX95042.1 - 0.041 13.6 2.4 0.078 12.7 2.4 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase Ribosomal_L17 PF01196.19 EAX95042.1 - 0.055 14.4 2.4 12 6.9 2.4 3.9 1 1 0 1 1 1 0 Ribosomal protein L17 GHL10 PF02638.15 EAX95042.1 - 0.1 11.7 2.1 0.19 10.8 0.3 1.9 1 1 0 2 2 2 0 Glycosyl hydrolase-like 10 SnAPC_2_like PF11035.8 EAX95042.1 - 0.13 12.4 2.1 0.17 12.0 1.9 1.4 1 1 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb HSP90 PF00183.18 EAX95043.1 - 9.7e-82 275.5 1.7 1.2e-81 275.3 1.7 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 EAX95043.1 - 0.039 13.9 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C34 PF05413.11 EAX95043.1 - 0.32 11.3 2.3 1.6 9.0 0.1 2.5 1 1 1 2 2 2 0 Putative closterovirus papain-like endopeptidase HSP90 PF00183.18 EAX95044.1 - 1.6e-46 159.3 19.4 2.1e-46 158.9 19.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EAX95044.1 - 2.7e-13 50.4 0.1 5.1e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAX95044.1 - 8.7e-10 38.6 0.0 8.7e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 EAX95044.1 - 0.058 13.5 10.6 0.091 12.9 10.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 EAX95044.1 - 0.085 13.1 11.4 0.15 12.4 11.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Fib_alpha PF08702.10 EAX95046.1 - 0.011 15.9 2.8 0.011 15.9 2.8 9.2 4 2 6 10 10 10 0 Fibrinogen alpha/beta chain family Dak2 PF02734.17 EAX95046.1 - 5.9 6.7 6.9 0.87 9.5 0.7 2.7 3 0 0 3 3 3 0 DAK2 domain SLATT_1 PF18181.1 EAX95046.1 - 6.5 6.7 14.7 4.7 7.2 0.1 5.2 5 1 2 7 7 7 0 SMODS and SLOG-associating 2TM effector domain 1 VPS9 PF02204.18 EAX95047.1 - 5.4e-06 26.6 0.2 1.6e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ANAPC1 PF12859.7 EAX95047.1 - 0.11 13.0 0.5 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF3839 PF12943.7 EAX95048.1 - 3.5e-145 481.8 15.9 3.9e-145 481.6 15.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX95048.1 - 0.031 14.0 3.0 0.84 9.3 1.0 2.7 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX95048.1 - 0.12 12.8 3.3 0.72 10.3 0.4 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX95048.1 - 1 9.7 6.1 2.4 8.5 0.1 3.2 2 2 0 2 2 2 0 Rx N-terminal domain Pox_A32 PF04665.12 EAX95050.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF3781 PF12636.7 EAX95051.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) RRM_1 PF00076.22 EAX95053.1 - 2.9e-12 46.2 0.1 1.2e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX95053.1 - 0.018 14.6 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3069 PF11269.8 EAX95053.1 - 0.043 14.1 0.4 0.075 13.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) ANAPC4_WD40 PF12894.7 EAX95054.1 - 2.6e-10 40.5 0.0 0.01 16.2 0.0 4.7 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX95054.1 - 1.2e-09 38.6 7.0 0.0031 18.3 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat COPIIcoated_ERV PF07970.12 EAX95055.1 - 7.7e-43 146.9 0.2 1e-42 146.5 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX95055.1 - 2.7e-16 59.7 0.4 4.7e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Rtf2 PF04641.12 EAX95056.1 - 1.9e-26 93.0 4.2 5e-26 91.6 4.2 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EAX95056.1 - 2.4e-06 27.3 4.1 2.4e-06 27.3 4.1 1.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAX95056.1 - 6.6e-05 22.8 4.0 0.00018 21.4 4.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAX95056.1 - 0.0013 18.6 0.7 0.0026 17.6 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.7 EAX95056.1 - 0.0095 15.9 2.4 0.67 9.9 1.9 2.3 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_2 PF13923.6 EAX95056.1 - 0.015 15.1 4.1 0.041 13.7 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX95056.1 - 0.047 13.7 1.7 0.047 13.7 1.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger RabGAP-TBC PF00566.18 EAX95056.1 - 0.071 12.8 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain zf-RING_2 PF13639.6 EAX95056.1 - 0.15 12.5 7.4 0.16 12.4 6.2 1.8 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EAX95056.1 - 2.1 8.3 7.3 4.7 7.2 6.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F5_F8_type_C PF00754.25 EAX95057.1 - 1.3e-08 35.1 0.0 6.9e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain KxDL PF10241.9 EAX95059.1 - 0.36 11.1 6.7 1 9.6 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein TMPIT PF07851.13 EAX95059.1 - 9.4 5.4 6.7 1.5 8.0 1.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein Pecanex_C PF05041.15 EAX95060.1 - 2.7e-25 89.3 0.0 5.9e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Peptidase_MA_2 PF13485.6 EAX95060.1 - 0.02 14.6 0.1 0.077 12.7 0.1 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily FHA PF00498.26 EAX95061.1 - 2.2e-05 24.7 0.1 4.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain R-HINP1I PF11463.8 EAX95061.1 - 0.12 11.8 1.2 0.62 9.5 0.4 2.1 1 1 1 2 2 2 0 R.HinP1I restriction endonuclease RRM_1 PF00076.22 EAX95062.1 - 8.6e-46 153.6 0.6 1.1e-15 57.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX95062.1 - 8.5e-10 38.3 0.0 0.0018 17.9 0.0 3.5 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX95062.1 - 2.3e-09 37.0 0.0 0.045 13.6 0.0 3.2 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAX95062.1 - 6.3e-06 26.1 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX95062.1 - 0.00017 21.6 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.11 EAX95062.1 - 0.00039 20.3 0.0 0.0024 17.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) Limkain-b1 PF11608.8 EAX95062.1 - 0.00091 19.3 0.1 1.6 8.9 0.0 3.5 3 1 0 3 3 3 1 Limkain b1 PHM7_cyt PF14703.6 EAX95062.1 - 0.078 13.2 0.0 23 5.2 0.0 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter E2 PF08199.11 EAX95062.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage E2-like protein CbiK PF06180.11 EAX95062.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Nucleoporin_FG PF13634.6 EAX95062.1 - 3.1 8.7 56.9 2.6 9.0 19.2 4.2 1 1 1 3 3 3 0 Nucleoporin FG repeat region HSP70 PF00012.20 EAX95063.1 - 8e-28 97.0 0.0 9.4e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX95063.1 - 0.018 13.9 0.0 1.2 7.9 0.0 2.4 2 1 0 2 2 2 0 MreB/Mbl protein OsmC PF02566.19 EAX95063.1 - 0.14 12.7 0.0 0.25 11.8 0.0 1.4 1 1 0 1 1 1 0 OsmC-like protein HSP70 PF00012.20 EAX95064.1 - 4.2e-24 84.7 12.3 9.6e-24 83.5 12.3 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX95064.1 - 0.011 14.6 0.1 0.027 13.3 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein G0-G1_switch_2 PF15103.6 EAX95065.1 - 0.051 14.0 2.3 0.16 12.4 0.1 2.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 Peptidase_S49_N PF08496.10 EAX95065.1 - 0.64 10.1 7.9 0.3 11.1 0.6 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HECT PF00632.25 EAX95066.1 - 1.6e-17 64.0 0.0 1.6e-17 64.0 0.0 3.1 2 1 1 3 3 3 1 HECT-domain (ubiquitin-transferase) MLD PF11647.8 EAX95066.1 - 0.14 12.5 3.3 0.14 12.4 0.3 2.6 2 0 0 2 2 2 0 Membrane Localization Domain VESA1_N PF12785.7 EAX95067.1 - 0.00036 19.6 0.7 0.00059 18.9 0.7 1.2 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 Tocopherol_cycl PF14249.6 EAX95067.1 - 0.057 12.5 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Tocopherol cyclase Bromodomain PF00439.25 EAX95068.1 - 2.6e-19 69.1 0.5 2.6e-19 69.1 0.5 1.9 2 0 0 2 2 2 1 Bromodomain DUF2373 PF10180.9 EAX95068.1 - 0.011 15.6 1.0 0.06 13.2 0.9 2.2 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Succ_DH_flav_C PF02910.20 EAX95068.1 - 0.024 14.6 0.2 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 Fumarate reductase flavoprotein C-term RNAse_A_bac PF18431.1 EAX95068.1 - 0.095 13.7 0.1 0.74 10.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain CorA PF01544.18 EAX95069.1 - 0.0033 16.8 13.8 0.048 13.0 2.7 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Trns_repr_metal PF02583.17 EAX95069.1 - 0.0047 17.3 1.8 3.3 8.2 0.8 2.6 2 0 0 2 2 2 2 Metal-sensitive transcriptional repressor FapA PF03961.13 EAX95069.1 - 0.01 14.5 19.1 0.011 14.3 4.6 2.0 1 1 1 2 2 2 1 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EAX95069.1 - 0.014 15.4 14.6 0.17 12.0 3.2 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2833 PF11090.8 EAX95069.1 - 0.018 15.4 2.5 1.2 9.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2833) PspB PF06667.12 EAX95069.1 - 0.031 14.3 10.3 0.034 14.2 0.7 3.5 2 1 2 4 4 4 0 Phage shock protein B TraB PF01963.17 EAX95069.1 - 0.037 13.9 8.8 0.077 12.9 8.8 1.5 1 1 0 1 1 1 0 TraB family FANCI_HD1 PF14679.6 EAX95069.1 - 0.044 13.7 2.1 0.77 9.8 0.0 2.8 2 1 0 2 2 2 0 FANCI helical domain 1 CENP-F_leu_zip PF10473.9 EAX95069.1 - 0.12 12.4 16.2 4.1 7.4 16.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSCB_C PF07743.13 EAX95069.1 - 0.17 12.4 10.7 0.72 10.4 1.3 3.3 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain Mt_ATP-synt_D PF05873.12 EAX95069.1 - 0.27 11.1 13.4 0.23 11.3 1.5 2.4 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) FliJ PF02050.16 EAX95069.1 - 0.3 11.3 15.8 0.097 12.9 3.2 2.5 1 1 0 2 2 2 0 Flagellar FliJ protein Patched PF02460.18 EAX95069.1 - 0.31 9.1 5.8 0.41 8.6 5.8 1.1 1 0 0 1 1 1 0 Patched family Syntaxin-6_N PF09177.11 EAX95069.1 - 0.42 11.2 14.4 81 3.9 14.2 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Tnp_22_trimer PF17489.2 EAX95069.1 - 0.53 10.3 11.1 0.63 10.0 1.0 3.7 3 1 0 3 3 3 0 L1 transposable element trimerization domain Osmo_CC PF08946.10 EAX95069.1 - 0.65 10.3 4.0 7.2 6.9 0.2 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF4085 PF13315.6 EAX95069.1 - 0.88 9.2 10.2 0.11 12.1 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Fib_alpha PF08702.10 EAX95069.1 - 1 9.6 21.2 3.9 7.7 13.0 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EAX95069.1 - 1.2 9.6 13.1 0.48 10.9 2.2 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PIN_8 PF18476.1 EAX95069.1 - 1.3 8.9 16.7 1.2 9.0 8.7 2.1 1 1 1 2 2 2 0 PIN like domain Muted PF14942.6 EAX95069.1 - 1.5 9.2 20.4 3.6 7.9 13.5 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TMPIT PF07851.13 EAX95069.1 - 1.8 7.7 18.7 1.3 8.2 7.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein COG5 PF10392.9 EAX95069.1 - 2 8.6 14.1 0.93 9.7 10.1 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 AvrM-A PF18241.1 EAX95069.1 - 3.6 8.0 14.4 4.7 7.6 12.7 2.0 2 1 1 3 3 2 0 Flax-rust effector AvrM-A LMBR1 PF04791.16 EAX95069.1 - 3.6 6.4 11.4 4.2 6.2 11.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WDCP PF15390.6 EAX95069.1 - 4.5 5.5 13.7 5.6 5.2 13.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Exonuc_VII_L PF02601.15 EAX95069.1 - 5.4 6.5 15.9 12 5.3 15.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Med4 PF10018.9 EAX95069.1 - 5.7 6.6 16.5 3.9e+03 -2.7 16.6 2.6 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Allexi_40kDa PF05549.11 EAX95069.1 - 6.3 6.2 15.1 1.3 8.5 4.3 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein COG2 PF06148.11 EAX95069.1 - 6.8 6.8 10.8 3.1 7.9 2.2 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 EAX95069.1 - 6.8 7.0 9.6 1.9 8.8 1.9 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mit_KHE1 PF10173.9 EAX95069.1 - 7.2 6.6 11.1 19 5.3 11.2 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Tubulin PF00091.25 EAX95070.1 - 6.7e-08 33.0 0.0 9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Thioredoxin PF00085.20 EAX95071.1 - 5.1e-19 68.2 0.0 5.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX95071.1 - 1.6e-05 25.3 0.0 0.0006 20.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EAX95071.1 - 7.8e-05 23.0 0.0 9.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 EAX95071.1 - 0.00021 20.8 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EAX95071.1 - 0.00038 20.7 0.1 0.0041 17.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAX95071.1 - 0.00066 19.8 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EAX95071.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EAX95071.1 - 0.0028 17.4 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EAX95071.1 - 0.003 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EAX95071.1 - 0.049 13.4 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 EAX95071.1 - 0.096 12.6 0.0 0.24 11.3 0.0 1.6 1 1 1 2 2 2 0 AhpC/TSA family HyaE PF07449.11 EAX95071.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EAX95071.1 - 0.18 11.5 0.3 6.4 6.5 0.1 2.0 1 1 1 2 2 2 0 Redoxin UCH PF00443.29 EAX95072.1 - 0.00056 19.5 1.5 0.016 14.7 1.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_S64 PF08192.11 EAX95072.1 - 0.002 16.7 0.6 0.023 13.2 0.0 2.0 2 0 0 2 2 2 2 Peptidase family S64 Fungal_lectin_2 PF18647.1 EAX95072.1 - 0.037 14.5 0.7 0.079 13.4 0.3 1.8 1 1 1 2 2 2 0 Alpha-galactosyl-binding fungal lectin DUF4107 PF13389.6 EAX95074.1 - 2.8e-71 238.9 3.4 3.7e-71 238.5 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX95075.1 - 0.0052 16.5 0.1 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase PapD_N PF00345.20 EAX95077.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX95077.1 - 0.051 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX95077.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX95078.1 - 0.017 15.5 0.4 0.022 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX95078.1 - 1.3 8.0 2.6 1.4 7.9 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX95078.1 - 3.6 7.6 5.8 3.8 7.5 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX95079.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX95080.1 - 0.038 14.0 8.7 0.059 13.4 8.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX95080.1 - 2.9 8.4 6.1 4.2 7.8 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX95081.1 - 0.11 11.5 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1522 PF07482.11 EAX95083.1 - 1 9.7 5.3 0.63 10.4 0.4 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1522) Ank_2 PF12796.7 EAX95084.1 - 1.1e-53 179.8 19.3 9.3e-18 64.6 2.9 6.6 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95084.1 - 2.8e-39 128.6 7.5 8.8e-06 25.7 0.1 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX95084.1 - 3e-39 132.6 16.9 2.4e-07 30.9 0.7 8.5 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95084.1 - 5.9e-39 132.0 11.9 6.2e-08 33.0 0.2 7.9 3 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX95084.1 - 1.3e-38 129.8 9.7 5.9e-06 26.5 0.1 9.3 8 1 1 9 9 9 7 Ankyrin repeat DUF3447 PF11929.8 EAX95084.1 - 2.6e-12 46.5 7.1 2.6e-12 46.5 7.1 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Exo70 PF03081.15 EAX95086.1 - 4.1e-53 180.8 4.1 4.1e-53 180.8 4.1 2.6 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Bromo_TP PF07524.13 EAX95086.1 - 0.0082 16.1 3.2 0.78 9.8 0.2 3.7 4 0 0 4 4 4 1 Bromodomain associated Spore_III_AB PF09548.10 EAX95086.1 - 0.0091 16.1 5.9 0.51 10.4 0.2 2.7 2 0 0 2 2 2 2 Stage III sporulation protein AB (spore_III_AB) ABC_tran_Xtn PF12848.7 EAX95086.1 - 0.013 15.5 1.7 0.013 15.5 1.7 2.3 2 0 0 2 2 2 0 ABC transporter DUF1664 PF07889.12 EAX95086.1 - 0.42 10.7 4.8 0.26 11.3 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) rRNA_proc-arch PF13234.6 EAX95086.1 - 1.7 8.5 9.3 0.18 11.7 2.7 2.6 3 1 0 3 3 3 0 rRNA-processing arch domain FPP PF05911.11 EAX95086.1 - 5.4 5.1 12.8 0.52 8.4 6.9 1.9 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4413 PF14372.6 EAX95086.1 - 7 7.1 8.4 1.8 9.0 0.6 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4413) DUF3447 PF11929.8 EAX95087.1 - 1.4e-09 37.8 0.4 1.4e-09 37.8 0.4 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3939 PF13075.6 EAX95087.1 - 0.029 14.4 1.6 0.029 14.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Ribosomal_S4 PF00163.19 EAX95088.1 - 0.00078 20.3 0.4 0.00086 20.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EAX95089.1 - 3.3e-07 29.9 0.1 4.5e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 S4 domain DUF3138 PF11336.8 EAX95090.1 - 0.028 13.1 3.4 0.032 12.8 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ank_2 PF12796.7 EAX95091.1 - 4.6e-10 39.9 0.2 3.7e-05 24.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95091.1 - 3.2e-08 33.2 3.4 0.019 15.5 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX95091.1 - 5.3e-05 23.7 0.2 0.075 13.6 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX95091.1 - 9.1e-05 22.7 0.0 0.11 12.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX95091.1 - 0.0051 17.1 0.0 0.028 14.7 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Mem_trans PF03547.18 EAX95093.1 - 7e-25 87.2 25.4 6.9e-18 64.2 8.3 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF3989 PF13150.6 EAX95093.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Pox_P21 PF05313.12 EAX95093.1 - 2.6 7.6 12.6 0.21 11.1 7.3 1.8 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Ldh_1_N PF00056.23 EAX95094.1 - 2.4e-33 115.2 0.0 3.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX95094.1 - 4.6e-29 101.5 0.0 7.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 EAX95094.1 - 0.0041 17.1 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain YdaS_antitoxin PF15943.5 EAX95094.1 - 0.045 13.6 0.1 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PLD_C PF12357.8 EAX95094.1 - 0.14 12.1 0.1 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Phospholipase D C terminal Glucokinase PF02685.16 EAX95095.1 - 2.4e-10 39.9 0.0 4.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EAX95095.1 - 0.0033 16.9 0.0 0.0077 15.7 0.0 1.6 2 0 0 2 2 2 1 ROK family RHD3 PF05879.12 EAX95096.1 - 3.3e-139 465.3 26.6 1.5e-130 436.7 16.4 2.1 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EAX95096.1 - 1.1e-05 25.4 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EAX95096.1 - 0.00029 21.0 0.1 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EAX95096.1 - 0.0025 17.9 0.0 0.0025 17.9 0.0 4.3 3 2 1 4 4 3 1 Dynamin family RNA_helicase PF00910.22 EAX95096.1 - 0.0047 17.3 0.7 0.13 12.7 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 EAX95096.1 - 0.0058 16.9 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAX95096.1 - 0.016 15.3 0.0 0.077 13.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX95096.1 - 0.028 14.8 0.7 0.42 11.0 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain HSCB_C PF07743.13 EAX95096.1 - 0.072 13.6 2.6 2.6 8.6 0.1 3.7 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain MRI PF15325.6 EAX95096.1 - 0.11 13.7 2.5 0.3 12.2 2.5 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection AAA_29 PF13555.6 EAX95096.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EAX95096.1 - 0.21 11.2 1.9 0.39 10.3 0.0 2.5 3 0 0 3 3 3 0 Ras family ABC_tran PF00005.27 EAX95096.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.2 2 1 0 2 2 1 0 ABC transporter TENA_THI-4 PF03070.16 EAX95096.1 - 0.41 10.4 4.9 2.3 8.0 0.0 3.2 3 1 0 3 3 3 0 TENA/THI-4/PQQC family RsgA_GTPase PF03193.16 EAX95096.1 - 3.7 7.4 5.8 0.53 10.2 0.1 2.4 3 0 0 3 3 3 0 RsgA GTPase Thioredoxin PF00085.20 EAX95097.1 - 6.9e-18 64.5 0.1 7.5e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EAX95097.1 - 2.2e-09 37.2 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX95097.1 - 4.7e-05 23.8 0.1 0.0028 18.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX95097.1 - 0.00013 22.2 0.4 0.0031 17.8 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 EAX95097.1 - 0.029 14.3 0.1 0.035 14.0 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 EAX95097.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Cation_efflux PF01545.21 EAX95098.1 - 4.3e-24 85.3 9.0 5.5e-24 85.0 9.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EAX95098.1 - 8.8e-09 35.4 0.2 1.6e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PHO4 PF01384.20 EAX95098.1 - 0.051 12.6 3.7 0.065 12.3 3.7 1.2 1 0 0 1 1 1 0 Phosphate transporter family SidE PF12252.8 EAX95099.1 - 0.0078 13.8 4.9 0.0084 13.7 4.9 1.1 1 0 0 1 1 1 1 Dot/Icm substrate protein DUF4446 PF14584.6 EAX95099.1 - 0.028 14.4 0.2 0.061 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Coat_F PF07875.12 EAX95099.1 - 0.093 13.0 0.6 0.49 10.7 0.1 2.3 2 0 0 2 2 2 0 Coat F domain UCH PF00443.29 EAX95100.1 - 4.6e-13 49.3 0.8 5.9e-11 42.4 0.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX95100.1 - 0.015 15.0 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase QueF PF14489.6 EAX95100.1 - 0.028 14.6 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 QueF-like protein LRR_5 PF13306.6 EAX95101.1 - 1.6e-74 247.9 50.4 5.9e-23 81.2 7.0 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95101.1 - 1.8e-26 91.7 12.4 1e-06 28.4 0.7 7.1 3 1 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 EAX95101.1 - 0.00061 20.1 17.3 2.8 8.5 1.5 7.0 3 2 2 7 7 7 3 Leucine Rich repeats (2 copies) Hexapep_2 PF14602.6 EAX95101.1 - 0.012 15.3 0.8 0.026 14.3 0.8 1.6 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase MFS18 PF17352.2 EAX95101.1 - 0.28 11.6 1.7 1.2 9.5 0.6 2.3 2 0 0 2 2 2 0 Male Flower Specific protein 18 FNIP PF05725.12 EAX95101.1 - 1.2 9.3 9.3 0.26 11.5 0.9 3.9 4 2 0 4 4 4 0 FNIP Repeat LRR_5 PF13306.6 EAX95102.1 - 2.7e-63 211.6 27.9 3.9e-26 91.5 3.7 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95102.1 - 1.1e-09 37.9 0.2 0.035 13.9 0.0 4.9 3 2 3 6 6 6 3 Leucine rich repeat Peptidase_C12 PF01088.21 EAX95103.1 - 6.8e-51 173.0 0.0 7.7e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Tape_meas_lam_C PF09718.10 EAX95105.1 - 0.15 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ABC_tran PF00005.27 EAX95106.1 - 1.5e-19 70.8 0.3 3.6e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAX95106.1 - 5.2e-06 26.5 0.2 0.00088 19.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EAX95106.1 - 0.074 13.3 0.0 3 8.1 0.0 2.8 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF1445 PF07286.12 EAX95106.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) Enterotoxin_b PF01376.18 EAX95106.1 - 0.11 12.7 0.3 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Heat-labile enterotoxin beta chain AAA PF00004.29 EAX95106.1 - 0.2 12.1 1.1 0.46 10.9 0.2 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCCH_4 PF18044.1 EAX95107.1 - 3.8e-06 26.5 2.4 7e-06 25.7 2.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAX95107.1 - 3.6e-05 23.7 6.0 7.7e-05 22.6 6.0 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EAX95107.1 - 0.015 15.2 0.4 0.031 14.2 0.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3612 PF12268.8 EAX95107.1 - 0.16 12.1 0.1 0.37 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3612) Gly_rich PF12810.7 EAX95108.1 - 7.4e-23 81.7 35.5 9.8e-23 81.3 35.5 1.0 1 0 0 1 1 1 1 Glycine rich protein Homeobox_KN PF05920.11 EAX95112.1 - 3.3e-16 58.9 0.6 5.9e-16 58.1 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAX95112.1 - 1.9e-11 43.6 0.4 3.2e-11 42.9 0.4 1.3 1 0 0 1 1 1 1 Homeodomain Raf1_HTH PF18579.1 EAX95112.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Topoisom_bac PF01131.20 EAX95113.1 - 1.6e-107 360.1 0.0 2.2e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EAX95113.1 - 5.6e-16 58.6 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Gly_rich PF12810.7 EAX95114.1 - 3.9e-52 177.6 28.1 4.7e-52 177.3 28.1 1.0 1 0 0 1 1 1 1 Glycine rich protein Hpr_kinase_N PF02603.16 EAX95116.1 - 0.076 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase N terminus Ank_2 PF12796.7 EAX95117.1 - 2.6e-48 162.5 29.0 1.8e-11 44.5 0.4 8.3 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95117.1 - 5.2e-38 128.9 10.7 1.4e-05 25.6 0.1 10.6 4 4 9 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95117.1 - 1.1e-32 108.3 4.8 0.0025 18.1 0.0 13.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 EAX95117.1 - 4.9e-32 109.6 13.6 2.6e-05 24.4 0.1 10.7 7 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX95117.1 - 1.8e-30 104.0 3.3 0.00035 20.9 0.0 11.7 11 0 0 11 11 11 6 Ankyrin repeat DUF3447 PF11929.8 EAX95117.1 - 7.3e-07 29.1 9.3 8.1e-07 28.9 2.4 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) RabGAP-TBC PF00566.18 EAX95118.1 - 4.5e-20 72.2 1.0 4.5e-20 72.2 1.0 2.2 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Ank PF00023.30 EAX95119.1 - 2e-15 56.4 0.1 5.6e-07 29.7 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX95119.1 - 2.3e-15 56.4 0.1 1.1e-07 32.0 0.0 1.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95119.1 - 1.7e-13 50.9 0.2 2e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95119.1 - 4.7e-13 49.4 0.0 9.4e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95119.1 - 8.5e-12 44.2 0.0 6.7e-05 23.0 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat LEM PF03020.15 EAX95119.1 - 0.011 15.2 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 LEM domain DUF4265 PF14085.6 EAX95119.1 - 0.019 14.9 0.1 0.031 14.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) BAT PF15915.5 EAX95119.1 - 0.057 13.3 0.1 2.8 7.8 0.1 1.9 1 1 0 1 1 1 0 GAF and HTH_10 associated domain Peptidase_M16 PF00675.20 EAX95119.1 - 0.073 13.0 0.1 0.53 10.3 0.0 1.9 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) DUF3447 PF11929.8 EAX95120.1 - 4.7e-16 58.5 4.7 4.7e-16 58.5 4.7 4.0 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX95120.1 - 2.7e-05 24.6 4.6 0.00012 22.6 1.3 3.1 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95120.1 - 0.002 18.5 0.2 0.12 13.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX95120.1 - 0.0027 18.3 0.5 0.011 16.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX95120.1 - 0.012 16.1 0.1 0.1 13.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat CLTH PF10607.9 EAX95120.1 - 0.1 12.5 2.5 0.27 11.1 2.3 2.0 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SAS-6_N PF16531.5 EAX95122.1 - 1.6e-14 54.3 4.1 3.2e-14 53.3 4.1 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Cep57_MT_bd PF06657.13 EAX95122.1 - 0.024 15.1 0.5 0.067 13.6 0.5 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Peptidase_M16_M PF16187.5 EAX95122.1 - 0.054 12.8 2.7 0.083 12.2 2.7 1.4 1 1 0 1 1 1 0 Middle or third domain of peptidase_M16 DUF2804 PF10974.8 EAX95123.1 - 1.1e-103 347.2 0.3 1.3e-103 347.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) DUF1115 PF06544.12 EAX95124.1 - 1.8e-18 67.0 0.2 1.8e-18 67.0 0.2 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 EAX95124.1 - 8.7e-13 48.5 21.5 8.7e-13 48.5 21.5 4.0 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) Ank_2 PF12796.7 EAX95125.1 - 2.7e-69 229.8 23.1 7.3e-17 61.7 0.3 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95125.1 - 2.9e-58 193.5 13.3 3.1e-11 43.6 0.1 5.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX95125.1 - 3.5e-58 191.7 9.0 2.6e-09 37.1 0.0 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 EAX95125.1 - 2e-47 153.6 7.5 4.4e-07 29.7 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAX95125.1 - 5.1e-46 154.1 15.7 1e-13 51.2 0.2 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) ThiS-like PF14453.6 EAX95125.1 - 8.8e-08 32.1 7.8 3.8 7.6 0.0 6.1 1 1 5 6 6 6 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX95125.1 - 1.4e-05 25.3 0.0 0.07 13.4 0.0 3.6 1 1 3 4 4 4 3 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX95125.1 - 0.0013 18.9 0.5 42 4.5 0.0 4.8 1 1 5 6 6 6 0 Pleckstrin homology domain DUF1877 PF08974.10 EAX95125.1 - 0.0016 18.6 0.1 0.99 9.5 0.0 2.8 1 1 3 4 4 4 1 Domain of unknown function (DUF1877) CEP44 PF15007.6 EAX95125.1 - 0.0069 16.5 0.0 17 5.6 0.0 3.9 1 1 4 5 5 5 0 Centrosomal spindle body, CEP44 CCG PF02754.16 EAX95125.1 - 0.0072 16.5 0.3 0.99 9.7 0.0 2.8 1 1 2 3 3 3 1 Cysteine-rich domain Phage_G PF02306.15 EAX95125.1 - 0.02 14.6 0.8 9.3 5.9 0.2 3.4 1 1 2 3 3 3 0 Major spike protein (G protein) Staphylokinase PF02821.16 EAX95125.1 - 0.024 15.1 0.4 1.6e+02 2.7 0.0 4.3 1 1 4 5 5 5 0 Staphylokinase/Streptokinase family GPI-anchored PF10342.9 EAX95125.1 - 0.075 13.8 0.5 8.2 7.3 0.1 3.4 1 1 3 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Defensin_3 PF08131.11 EAX95125.1 - 0.41 10.9 1.9 57 4.0 0.1 3.4 3 0 0 3 3 3 0 Defensin-like peptide family AbrB_C PF18277.1 EAX95125.1 - 2.7 7.7 7.8 2.7e+02 1.3 0.0 5.2 6 0 0 6 6 6 0 AbrB C-terminal domain Ank_2 PF12796.7 EAX95126.1 - 6.4e-65 215.7 26.0 1.2e-13 51.4 0.2 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95126.1 - 4.7e-60 197.6 12.0 2.2e-08 34.2 0.1 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EAX95126.1 - 6.1e-55 182.9 15.6 2.2e-11 44.0 0.0 7.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95126.1 - 4.6e-49 158.7 7.8 9.4e-06 25.6 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX95126.1 - 1.2e-40 137.0 9.9 3.4e-12 46.3 0.3 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) ThiS-like PF14453.6 EAX95126.1 - 0.00021 21.3 9.8 21 5.3 0.0 7.2 3 1 4 7 7 7 0 ThiS-like ubiquitin MetallophosN PF16371.5 EAX95126.1 - 0.00071 19.8 0.0 4 7.8 0.0 4.1 2 1 2 4 4 4 1 N terminal of Calcineurin-like phosphoesterase Phage_G PF02306.15 EAX95126.1 - 0.0023 17.7 0.7 2.1 8.0 0.0 4.0 2 1 4 6 6 6 1 Major spike protein (G protein) GPI-anchored PF10342.9 EAX95126.1 - 0.076 13.8 0.9 73 4.2 0.0 3.7 1 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDC73_C PF05179.14 EAX95126.1 - 1.3 8.7 12.9 4 7.1 0.1 5.6 5 0 0 5 5 5 0 RNA pol II accessory factor, Cdc73 family, C-terminal L_lac_phage_MSP PF06488.11 EAX95126.1 - 9.6 5.4 25.7 57 2.8 0.2 9.0 2 1 9 12 12 12 0 Phage tail tube protein Ank_2 PF12796.7 EAX95127.1 - 4e-115 376.6 55.1 2.4e-18 66.5 3.6 8.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95127.1 - 4.5e-101 327.3 25.1 3.9e-09 36.5 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.6 EAX95127.1 - 1.1e-98 322.4 35.5 8e-12 45.4 0.1 11.8 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95127.1 - 7.8e-92 300.1 44.5 2.5e-11 43.6 0.2 7.5 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95127.1 - 2.9e-81 257.6 19.8 1.3e-06 28.2 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat ThiS-like PF14453.6 EAX95127.1 - 1.9e-11 43.8 19.2 7.7 6.7 0.0 11.8 2 1 10 12 12 12 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX95127.1 - 7.1e-10 39.0 0.0 0.53 10.6 0.0 5.2 5 2 1 6 6 5 3 N terminal of Calcineurin-like phosphoesterase Phage_G PF02306.15 EAX95127.1 - 1.8e-05 24.6 9.2 7.7 6.2 0.1 6.7 1 1 6 8 8 8 1 Major spike protein (G protein) PH_8 PF15409.6 EAX95127.1 - 9.1e-05 22.7 4.0 2.2e+02 2.2 0.0 8.1 1 1 9 11 11 11 0 Pleckstrin homology domain AnkUBD PF18418.1 EAX95127.1 - 0.0077 16.4 0.0 47 4.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain Staphylokinase PF02821.16 EAX95127.1 - 0.008 16.6 3.2 2.5e+02 2.1 0.0 6.7 1 1 5 8 8 8 0 Staphylokinase/Streptokinase family CCG PF02754.16 EAX95127.1 - 0.037 14.3 1.4 82 3.5 0.0 4.5 4 0 0 4 4 3 0 Cysteine-rich domain GPI-anchored PF10342.9 EAX95127.1 - 0.12 13.1 1.4 58 4.6 0.1 4.4 2 1 1 5 5 5 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PUB_1 PF18486.1 EAX95127.1 - 0.15 11.9 0.3 1.6e+02 2.2 0.0 3.8 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain Defensin_3 PF08131.11 EAX95127.1 - 0.43 10.8 2.5 1.5e+02 2.7 0.1 3.7 3 0 0 3 3 3 0 Defensin-like peptide family DUF1947 PF09183.10 EAX95128.1 - 0.0038 17.5 4.9 0.11 12.8 0.3 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1947) DUF4795 PF16043.5 EAX95128.1 - 0.0077 15.8 9.7 0.19 11.3 3.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) MULE PF10551.9 EAX95129.1 - 2.5e-11 43.8 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX95129.1 - 0.012 16.0 0.7 0.27 11.7 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) DUF4065 PF13274.6 EAX95129.1 - 0.13 13.2 0.3 2.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) FLYWCH PF04500.16 EAX95129.1 - 0.14 12.3 3.9 0.27 11.4 3.9 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Serinc PF03348.15 EAX95130.1 - 2.2e-22 79.6 21.7 4.6e-15 55.5 7.5 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) DUF2663 PF10864.8 EAX95130.1 - 0.3 11.5 14.8 1.2 9.6 0.9 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2663) DUF998 PF06197.13 EAX95130.1 - 0.4 10.2 6.8 0.64 9.6 0.2 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF998) Ank_2 PF12796.7 EAX95131.1 - 4.8e-32 110.4 11.1 2e-12 47.5 0.1 6.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95131.1 - 6.8e-25 84.4 4.2 0.0036 17.7 0.0 9.9 10 1 1 11 11 11 4 Ankyrin repeat Ank_4 PF13637.6 EAX95131.1 - 1.1e-19 70.5 3.4 6e-05 23.5 0.0 7.9 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95131.1 - 6.4e-17 61.4 0.0 0.0064 16.8 0.0 6.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX95131.1 - 5.4e-12 45.6 0.3 0.003 17.9 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 EAX95131.1 - 1.6e-05 24.7 0.4 1.6e-05 24.7 0.4 6.2 3 2 5 8 8 8 3 Domain of unknown function (DUF3447) Hydrolase_4 PF12146.8 EAX95131.1 - 0.064 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MCM_N PF14551.6 EAX95131.1 - 0.079 13.5 1.9 0.39 11.3 1.9 2.2 1 0 0 1 1 1 0 MCM N-terminal domain DUF1759 PF03564.15 EAX95131.1 - 0.21 11.5 4.4 0.11 12.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Propep_M14 PF02244.16 EAX95131.1 - 7.9 7.0 7.7 16 6.0 0.3 4.0 5 0 0 5 5 5 0 Carboxypeptidase activation peptide Myb_DNA-binding PF00249.31 EAX95132.1 - 5.6e-29 100.1 0.5 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95132.1 - 5.5e-27 93.8 5.2 3.5e-17 62.4 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX95132.1 - 2.2e-07 30.7 0.8 2e-05 24.4 0.2 2.4 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX95132.1 - 8.5e-06 25.8 1.4 0.012 15.6 0.0 2.7 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EAX95132.1 - 1.1e-05 25.5 0.9 3e-05 24.1 0.4 2.0 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX95132.1 - 0.043 13.9 0.0 3.8 7.7 0.0 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX95132.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain KI67R PF08065.12 EAX95134.1 - 0.072 13.6 5.4 0.051 14.1 2.8 1.9 1 1 1 2 2 2 0 KI67R (NUC007) repeat Presenilin PF01080.17 EAX95134.1 - 1.2 7.9 2.7 1.4 7.6 2.7 1.0 1 0 0 1 1 1 0 Presenilin PSP PF04046.16 EAX95135.1 - 0.077 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95136.1 - 0.099 13.3 4.8 17 6.7 0.2 3.5 3 1 0 3 3 3 0 TMP repeat GPS2_interact PF15784.5 EAX95137.1 - 0.036 14.5 0.5 0.049 14.1 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain T5orf172 PF10544.9 EAX95138.1 - 2.3e-06 28.1 0.2 6.7e-06 26.6 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX95138.1 - 0.015 14.8 1.2 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX95138.1 - 0.017 15.0 0.0 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 KilA-N domain UCH PF00443.29 EAX95140.1 - 2.9e-34 118.7 3.2 3.8e-34 118.3 3.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX95140.1 - 1.1e-12 48.2 12.9 4.4e-11 42.9 12.9 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_26 PF13500.6 EAX95141.1 - 0.06 13.2 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EAX95142.1 - 3.7e-47 158.8 1.7 2.6e-14 53.5 0.0 6.7 4 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95142.1 - 3.2e-39 132.8 1.5 1.2e-11 44.9 0.0 8.9 9 1 1 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95142.1 - 2.2e-37 126.6 2.6 2.4e-06 27.7 0.0 9.9 4 2 6 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95142.1 - 9.7e-34 111.6 4.9 9.6e-07 28.7 0.0 12.7 12 1 1 13 13 13 5 Ankyrin repeat Ank PF00023.30 EAX95142.1 - 3.7e-29 99.9 0.0 3e-07 30.6 0.0 10.3 8 2 2 10 10 10 5 Ankyrin repeat Erg28 PF03694.13 EAX95142.1 - 0.056 13.8 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Erg28 like protein DUF4903 PF16246.5 EAX95142.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) Enkurin PF13864.6 EAX95143.1 - 1.6e-13 50.9 4.9 1.6e-13 50.9 4.9 1.7 2 0 0 2 2 2 1 Calmodulin-binding Sas6_CC PF18594.1 EAX95143.1 - 0.11 12.3 3.8 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Pkinase PF00069.25 EAX95144.1 - 3.3e-60 203.7 0.0 4.7e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95144.1 - 7.8e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX95144.1 - 0.0031 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX95144.1 - 0.037 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Kinase-like RNA_pol_3_Rpc31 PF11705.8 EAX95144.1 - 8.6 6.5 12.3 19 5.4 12.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Histone PF00125.24 EAX95145.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX95145.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX95145.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX95145.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Chromo PF00385.24 EAX95146.1 - 3.2e-13 49.3 3.7 8.4e-13 48.0 3.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAX95146.1 - 4.2e-06 26.8 0.3 0.055 13.6 0.1 2.5 2 0 0 2 2 2 2 Chromo shadow domain ANAPC9 PF12856.7 EAX95146.1 - 0.0031 17.7 3.6 0.0031 17.7 3.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 I_LWEQ PF01608.17 EAX95147.1 - 2.2e-06 28.0 4.2 2.2e-06 28.0 4.2 6.9 7 2 1 8 8 8 1 I/LWEQ domain DASH_Dam1 PF08653.10 EAX95147.1 - 0.012 15.4 3.9 0.21 11.4 0.3 4.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 IL22 PF14565.6 EAX95147.1 - 0.014 15.6 0.4 0.068 13.4 0.4 2.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor PilJ PF13675.6 EAX95147.1 - 0.025 14.6 5.8 0.14 12.2 0.8 4.2 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term MinE PF03776.14 EAX95147.1 - 0.059 13.4 0.1 0.41 10.7 0.1 2.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Mating_N PF12731.7 EAX95147.1 - 2.6 8.2 8.9 17 5.6 0.0 6.3 5 1 1 6 6 6 0 Mating-type protein beta 1 Fungal_TACC PF12709.7 EAX95147.1 - 3.4 8.2 8.8 0.66 10.5 1.9 3.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Myb_DNA-binding PF00249.31 EAX95149.1 - 6.6e-30 103.1 0.6 1.3e-15 57.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95149.1 - 4.8e-24 84.4 3.3 8.2e-17 61.2 1.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX95149.1 - 0.001 19.2 1.2 5.3 7.3 0.5 3.3 2 1 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EAX95149.1 - 0.0059 16.6 6.8 0.81 9.7 0.0 3.7 2 2 1 3 3 3 2 SLIDE TFIIA PF03153.13 EAX95149.1 - 0.0098 15.9 15.6 0.01 15.8 15.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_7 PF15963.5 EAX95149.1 - 0.021 14.7 6.2 0.16 11.9 0.0 3.9 2 1 2 4 4 4 0 Myb DNA-binding like HTH_32 PF13565.6 EAX95149.1 - 0.053 14.1 0.2 1.6 9.4 0.0 2.4 1 1 1 2 2 2 0 Homeodomain-like domain NuiA PF07924.11 EAX95149.1 - 0.53 10.7 0.1 0.53 10.7 0.1 2.3 2 1 0 2 2 2 0 Nuclease A inhibitor-like protein Myb_DNA-bind_5 PF13873.6 EAX95149.1 - 0.9 9.7 6.0 6.7 6.9 0.6 3.7 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain VPS9 PF02204.18 EAX95150.1 - 3.1e-05 24.1 0.8 8.7e-05 22.7 0.8 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF4580 PF15162.6 EAX95150.1 - 0.026 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Suv3_C_1 PF18147.1 EAX95150.1 - 0.064 13.1 0.1 23 4.9 0.0 3.3 3 0 0 3 3 3 0 Suv3 C-terminal domain 1 Myb_DNA-binding PF00249.31 EAX95151.1 - 5.4e-24 84.1 0.3 3.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95151.1 - 2.7e-20 72.4 0.1 4.2e-11 42.9 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95151.1 - 8.5e-06 25.8 0.0 0.14 12.2 0.1 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95151.1 - 0.00029 20.7 0.6 0.0038 17.1 0.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX95151.1 - 0.0015 18.7 0.2 0.0034 17.5 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX95151.1 - 0.013 15.9 3.8 1.7 9.1 0.0 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain BES1_N PF05687.13 EAX95151.1 - 9.5 6.6 8.1 18 5.7 8.1 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Myb_DNA-binding PF00249.31 EAX95152.1 - 5.4e-24 84.1 0.3 3.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95152.1 - 2.7e-20 72.4 0.1 4.2e-11 42.9 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95152.1 - 8.5e-06 25.8 0.0 0.14 12.2 0.1 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95152.1 - 0.00029 20.7 0.6 0.0038 17.1 0.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX95152.1 - 0.0015 18.7 0.2 0.0034 17.5 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX95152.1 - 0.013 15.9 3.8 1.7 9.1 0.0 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain BES1_N PF05687.13 EAX95152.1 - 9.5 6.6 8.1 18 5.7 8.1 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TetR_C_4 PF08359.11 EAX95153.1 - 0.088 13.0 4.6 0.2 11.8 4.6 1.6 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DUF1664 PF07889.12 EAX95153.1 - 0.8 9.7 17.7 0.11 12.5 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 EAX95153.1 - 0.83 9.8 12.2 0.3 11.2 4.7 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 EAX95153.1 - 1.5 7.6 30.1 0.091 11.6 24.4 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EAX95153.1 - 2 8.5 9.3 3.4 7.7 7.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.9 EAX95153.1 - 5.1 5.5 34.3 11 4.4 34.3 1.5 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 EAX95154.1 - 2.2e-27 95.0 6.4 2.1e-14 53.4 0.2 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95154.1 - 2.3e-22 79.0 3.2 1e-12 48.1 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX95154.1 - 0.012 15.8 0.1 0.28 11.4 0.0 2.7 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX95154.1 - 0.02 14.7 6.3 0.79 9.7 0.0 3.2 1 1 3 4 4 4 0 Myb DNA-binding like DUF4167 PF13763.6 EAX95154.1 - 0.083 13.0 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) AHD PF17793.1 EAX95155.1 - 0.071 12.9 0.5 0.17 11.7 0.5 1.6 1 0 0 1 1 1 0 ANC1 homology domain (AHD) DUF3082 PF11282.8 EAX95155.1 - 2.5 8.4 6.6 0.73 10.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) SpoVAB PF13782.6 EAX95155.1 - 8.7 6.7 8.8 1 9.7 1.8 2.8 3 0 0 3 3 3 0 Stage V sporulation protein AB LRR_5 PF13306.6 EAX95156.1 - 5.2e-24 84.6 26.5 8.5e-19 67.8 14.7 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95156.1 - 2.4e-07 30.4 0.6 0.062 13.1 0.2 3.9 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EAX95156.1 - 0.00083 19.7 4.0 2 9.0 0.1 3.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) F5_F8_type_C PF00754.25 EAX95157.1 - 9.5e-07 29.0 0.0 2.7e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain Gly_rich PF12810.7 EAX95158.1 - 5.3e-07 29.8 12.5 7.4e-07 29.3 12.5 1.1 1 0 0 1 1 1 1 Glycine rich protein Pox_A32 PF04665.12 EAX95159.1 - 3.4e-05 23.4 3.0 3.7e-05 23.3 2.1 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX95159.1 - 0.0071 16.4 1.1 0.015 15.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX95159.1 - 0.01 15.5 0.3 0.02 14.5 0.3 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX95159.1 - 0.047 14.0 2.1 0.1 12.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX95159.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 F5_F8_type_C PF00754.25 EAX95161.1 - 5.4e-05 23.3 0.4 0.00068 19.8 0.0 2.3 3 0 0 3 3 3 1 F5/8 type C domain Transthyretin PF00576.21 EAX95162.1 - 3.1 8.5 5.7 20 5.9 2.6 3.6 3 0 0 3 3 3 0 HIUase/Transthyretin family ABC_membrane PF00664.23 EAX95163.1 - 6.2e-47 160.5 6.6 9.1e-47 160.0 6.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX95163.1 - 2.3e-34 118.9 0.0 5.6e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 EAX95163.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Cyt_bd_oxida_II PF02322.15 EAX95163.1 - 0.016 14.6 3.1 0.048 13.0 0.2 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II AAA_29 PF13555.6 EAX95163.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EAX95163.1 - 0.052 13.9 0.1 0.13 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX95163.1 - 0.055 13.7 0.1 0.19 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EAX95164.1 - 1.8e-17 63.4 1.8 8.2e-06 26.5 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95164.1 - 4.4e-15 55.7 0.0 0.00056 20.2 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX95164.1 - 2.2e-09 37.1 2.0 6e-06 25.8 1.0 2.4 1 1 1 2 2 2 2 WD40-like domain TolB_like PF15869.5 EAX95164.1 - 3.4e-06 26.5 0.7 3.8e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 TolB-like 6-blade propeller-like Lgl_C PF08596.10 EAX95164.1 - 0.0043 15.8 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal BBS1 PF14779.6 EAX95164.1 - 0.017 14.6 0.3 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 EAX95164.1 - 0.022 14.8 0.0 6.7 6.8 0.0 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ASFV_p27 PF06556.11 EAX95164.1 - 0.023 14.8 1.0 0.055 13.6 1.0 1.7 1 1 0 1 1 1 0 IAP-like protein p27 C-terminus Cytochrom_D1 PF02239.16 EAX95164.1 - 0.091 11.3 0.0 0.24 9.9 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Gly_rich PF12810.7 EAX95165.1 - 3.6e-38 131.9 42.0 4.3e-38 131.6 42.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank_2 PF12796.7 EAX95166.1 - 2e-27 95.6 15.5 7.5e-10 39.3 0.4 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95166.1 - 1.8e-22 79.4 8.3 0.00064 20.2 0.0 6.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95166.1 - 4.8e-14 51.1 13.7 0.039 14.5 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX95166.1 - 2.6e-13 49.9 5.2 1.5e-05 25.2 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX95166.1 - 1.3e-10 41.2 10.0 0.31 11.6 0.1 6.1 6 1 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX95167.1 - 6.5e-23 81.1 1.9 1.4e-10 41.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95167.1 - 9.5e-22 77.1 3.8 2.5e-10 40.7 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95167.1 - 3.7e-21 74.9 3.5 6.2e-10 39.1 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95167.1 - 1.8e-18 64.7 3.0 0.00041 20.6 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EAX95167.1 - 3.7e-16 58.8 4.3 0.0029 18.0 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EAX95167.1 - 0.00043 20.2 11.0 0.0038 17.2 3.2 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF3447) RBDV_coat PF06593.11 EAX95167.1 - 0.0014 18.2 0.5 0.0017 17.9 0.5 1.1 1 0 0 1 1 1 1 Raspberry bushy dwarf virus coat protein Clathrin PF00637.20 EAX95167.1 - 0.01 15.7 0.2 0.076 12.9 0.0 2.0 1 1 1 2 2 2 0 Region in Clathrin and VPS Pro_isomerase PF00160.21 EAX95168.1 - 1.3e-15 58.1 0.0 1.5e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Beta_helix PF13229.6 EAX95169.1 - 1.2e-05 25.2 17.9 0.0024 17.8 2.9 2.2 1 1 1 2 2 2 2 Right handed beta helix region DUF3836 PF12930.7 EAX95169.1 - 0.02 14.6 1.4 0.05 13.4 1.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF3836) NosD PF05048.13 EAX95169.1 - 0.1 11.8 14.8 0.14 11.4 11.4 2.5 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Topoisom_bac PF01131.20 EAX95170.1 - 6.2e-86 289.0 0.0 7.7e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase HTH_34 PF13601.6 EAX95170.1 - 0.019 15.2 0.2 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Pkinase PF00069.25 EAX95171.1 - 7.7e-50 169.7 0.0 9.8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95171.1 - 1e-28 100.3 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95171.1 - 1.7e-08 34.1 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX95171.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 EAX95171.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 EAX95171.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Amnionless PF14828.6 EAX95172.1 - 0.034 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Beta_helix PF13229.6 EAX95173.1 - 0.42 10.5 15.7 0.032 14.1 6.6 2.4 1 1 1 2 2 2 0 Right handed beta helix region DUF4448 PF14610.6 EAX95174.1 - 0.0048 16.7 0.2 0.0092 15.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Orf78 PF06024.12 EAX95174.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF4107 PF13389.6 EAX95176.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Peptidase_M8 PF01457.16 EAX95177.1 - 3.4e-31 108.5 0.0 8.1e-31 107.3 0.0 1.5 2 0 0 2 2 2 1 Leishmanolysin Peptidase_M8 PF01457.16 EAX95178.1 - 2.5e-30 105.7 0.0 1.5e-28 99.8 0.0 2.1 2 0 0 2 2 2 2 Leishmanolysin Mid2 PF04478.12 EAX95178.1 - 0.004 17.0 0.1 0.008 16.0 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAX95178.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family FGFR3_TM PF18123.1 EAX95178.1 - 2.2 7.9 6.1 3.9 7.1 6.1 1.4 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain NOT2_3_5 PF04153.18 EAX95179.1 - 7.1e-16 58.5 0.4 1.2e-15 57.7 0.4 1.4 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DnaJ PF00226.31 EAX95180.1 - 8.8e-09 35.4 0.8 8.8e-09 35.4 0.8 2.0 2 0 0 2 2 2 1 DnaJ domain Sin3_corepress PF08295.12 EAX95180.1 - 1e-08 35.1 0.1 2.9e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Vac_Fusion PF02346.16 EAX95180.1 - 0.096 12.3 0.1 0.32 10.7 0.1 2.0 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Pkinase PF00069.25 EAX95182.1 - 8.2e-48 163.1 0.0 9.8e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95182.1 - 1.6e-24 86.6 0.0 1.9e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX95182.1 - 6.3e-08 31.8 0.0 8.9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX95182.1 - 0.0099 15.2 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAX95182.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 EAX95183.1 - 1.5e-21 76.8 0.9 3.4e-11 43.6 0.1 3.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95183.1 - 5.4e-20 71.2 0.2 5.3e-08 33.0 0.0 4.5 2 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95183.1 - 1.6e-18 66.8 1.2 0.0012 19.3 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95183.1 - 1e-15 56.3 0.2 0.00056 20.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX95183.1 - 1e-13 51.0 2.0 0.00011 22.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Trimer_CC PF08954.11 EAX95183.1 - 0.0073 15.8 1.0 0.032 13.8 1.0 2.1 1 0 0 1 1 1 1 Trimerisation motif Exonuc_VII_L PF02601.15 EAX95183.1 - 0.044 13.3 2.5 0.076 12.6 2.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 EAX95183.1 - 0.087 10.8 11.1 1.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Prominin Pkinase PF00069.25 EAX95184.1 - 1.2e-54 185.5 0.0 1.6e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95184.1 - 7.6e-37 127.0 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95184.1 - 1.2e-07 31.3 0.0 2.9e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX95184.1 - 0.0011 18.3 0.1 0.0029 17.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX95184.1 - 0.014 15.4 0.0 0.2 11.6 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX95184.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CAF1 PF04857.20 EAX95186.1 - 7.9e-22 77.8 1.9 3e-13 49.6 0.2 2.6 2 1 0 2 2 2 2 CAF1 family ribonuclease Lsm_C PF14894.6 EAX95186.1 - 0.057 13.2 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Lsm C-terminal CNV-Replicase_N PF16688.5 EAX95186.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 DUF2004 PF09406.10 EAX95186.1 - 0.1 12.9 0.0 0.87 9.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) LRR_5 PF13306.6 EAX95187.1 - 2.8e-59 198.7 68.9 1.5e-22 79.9 11.7 5.2 2 1 4 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95187.1 - 2.1e-08 33.8 4.2 0.4 10.5 0.0 6.0 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAX95187.1 - 6.1e-07 29.7 10.5 0.3 11.6 0.2 6.5 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) Orf78 PF06024.12 EAX95187.1 - 0.0066 16.7 0.7 0.014 15.7 0.7 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Pentapeptide_3 PF13576.6 EAX95187.1 - 0.032 14.4 10.5 0.3 11.3 3.2 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) SDA1 PF05285.12 EAX95187.1 - 0.053 13.0 2.9 0.075 12.4 2.9 1.1 1 0 0 1 1 1 0 SDA1 Pentapeptide_4 PF13599.6 EAX95187.1 - 1.3 9.2 14.6 4.1 7.6 4.5 3.6 2 2 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_5 PF13306.6 EAX95188.1 - 2.1e-16 60.0 17.0 5e-16 58.8 13.2 2.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95188.1 - 0.0037 17.0 0.0 0.63 9.8 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 EAX95189.1 - 2.8e-100 331.2 137.5 1.2e-22 80.3 18.5 9.6 3 2 7 11 11 11 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95189.1 - 3.6e-12 45.9 0.7 0.42 10.4 0.0 8.9 9 1 2 11 11 11 4 Leucine rich repeat GutM PF06923.11 EAX95189.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) LRR_9 PF14580.6 EAX95190.1 - 8.3e-13 48.2 3.4 2.4e-10 40.2 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EAX95190.1 - 4e-10 39.8 10.3 1.9e-07 31.3 1.6 3.3 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX95190.1 - 6.8e-10 38.6 14.8 2.5e-05 24.0 0.9 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 EAX95190.1 - 0.14 12.8 1.1 22 6.1 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 EAX95190.1 - 1.2 9.3 5.2 28 5.1 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat WD40 PF00400.32 EAX95191.1 - 5e-26 90.5 11.2 7.3e-07 29.8 0.3 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95191.1 - 5.8e-17 61.8 0.0 2.4e-06 27.7 0.0 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EAX95191.1 - 1.5e-05 25.0 0.0 0.026 14.6 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.14 EAX95191.1 - 0.00034 19.8 0.6 0.00081 18.5 0.2 1.8 2 1 1 3 3 3 1 Coatomer WD associated region WD40_like PF17005.5 EAX95191.1 - 0.00046 19.6 0.7 0.46 9.8 0.1 2.3 2 0 0 2 2 2 2 WD40-like domain RAB3GAP2_N PF14655.6 EAX95191.1 - 0.075 12.3 0.9 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 EAX95191.1 - 0.084 11.2 0.0 0.31 9.3 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EAX95191.1 - 0.089 10.8 0.0 0.25 9.3 0.0 1.6 2 0 0 2 2 2 0 IKI3 family PQQ_2 PF13360.6 EAX95191.1 - 0.11 12.1 0.0 0.51 9.9 0.0 2.1 3 0 0 3 3 3 0 PQQ-like domain Ank_2 PF12796.7 EAX95192.1 - 1.1e-68 227.7 52.3 1.9e-18 66.8 5.1 6.3 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95192.1 - 2.6e-52 174.5 17.8 2.2e-11 44.0 0.2 8.9 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX95192.1 - 9.8e-48 158.6 13.5 2.5e-08 34.0 0.1 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX95192.1 - 2.4e-39 128.8 19.2 6.8e-06 26.0 0.1 10.5 10 1 1 11 11 11 7 Ankyrin repeat DUF3447 PF11929.8 EAX95192.1 - 1.1e-38 131.0 6.3 1.1e-38 131.0 6.3 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX95192.1 - 2e-32 110.8 11.1 2.9e-09 37.0 0.1 6.9 3 2 4 7 7 7 5 Ankyrin repeats (many copies) CEP44 PF15007.6 EAX95192.1 - 0.0098 16.1 0.6 2.3 8.4 0.0 4.0 1 1 3 4 4 4 1 Centrosomal spindle body, CEP44 ThiS-like PF14453.6 EAX95192.1 - 0.013 15.6 4.1 2.2 8.4 0.4 4.2 1 1 3 4 4 4 0 ThiS-like ubiquitin EHN PF06441.12 EAX95192.1 - 0.026 14.9 0.3 13 6.2 0.1 3.7 1 1 3 4 4 4 0 Epoxide hydrolase N terminus KdgM PF06178.13 EAX95192.1 - 0.31 10.6 5.3 5.2 6.6 0.1 2.9 3 0 0 3 3 3 0 Oligogalacturonate-specific porin protein (KdgM) Ribosomal_S28e PF01200.18 EAX95194.1 - 6.2e-31 106.2 2.9 7.1e-31 106.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e zf-RING_5 PF14634.6 EAX95196.1 - 0.0029 17.5 5.9 0.0081 16.1 5.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EAX95196.1 - 0.0034 17.0 0.3 0.007 16.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 EAX95196.1 - 0.0086 16.3 0.5 0.0086 16.3 0.5 3.4 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 EAX95196.1 - 0.019 14.7 2.7 0.055 13.2 2.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 EAX95196.1 - 0.022 15.1 0.5 0.022 15.1 0.5 1.9 2 0 0 2 2 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 EAX95196.1 - 0.025 14.7 0.6 0.071 13.3 0.2 1.9 2 0 0 2 2 1 0 PHD-zinc-finger like domain zf-rbx1 PF12678.7 EAX95196.1 - 0.033 14.5 1.5 0.092 13.1 1.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EAX95196.1 - 0.067 13.2 0.4 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger OSCP PF00213.18 EAX95196.1 - 0.086 13.0 0.4 0.42 10.7 0.1 2.3 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit C1_1 PF00130.22 EAX95196.1 - 0.091 12.7 0.6 0.2 11.6 0.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS91 PF14319.6 EAX95196.1 - 0.12 12.5 0.2 0.31 11.1 0.2 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain TPR_14 PF13428.6 EAX95196.1 - 0.13 13.1 0.0 5.7 8.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DZR PF12773.7 EAX95196.1 - 1.6 8.8 4.4 8.8 6.5 4.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EAX95196.1 - 7.2 6.5 8.5 0.25 11.2 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EAX95196.1 - 9.9 6.3 7.6 0.64 10.1 1.3 2.2 2 0 0 2 2 2 0 Zinc-finger PWI PF01480.17 EAX95197.1 - 2e-05 24.8 1.2 4.8e-05 23.6 1.2 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EAX95197.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX95197.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CC2D2AN-C2 PF15625.6 EAX95198.1 - 4e-20 72.2 0.0 9.1e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain Transglut_core PF01841.19 EAX95198.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily UCH PF00443.29 EAX95199.1 - 3.1e-13 49.8 0.6 5e-13 49.1 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX95199.1 - 0.0025 17.5 2.7 0.0031 17.2 1.1 1.6 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX95199.1 - 0.05 13.1 0.9 0.15 11.5 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase KilA-N PF04383.13 EAX95201.1 - 4e-41 139.4 1.1 7.3e-41 138.5 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain PapD_N PF00345.20 EAX95202.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX95202.1 - 0.027 14.4 0.3 0.036 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX95202.1 - 0.05 13.6 0.2 0.06 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX95203.1 - 0.017 15.5 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX95203.1 - 1.6 8.8 5.5 1.7 8.7 5.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX95204.1 - 0.021 14.8 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX95205.1 - 0.026 14.5 7.8 0.041 13.9 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX95206.1 - 0.028 14.8 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX95206.1 - 0.1 11.6 0.1 0.096 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain C2 PF00168.30 EAX95208.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain FBPase PF00316.20 EAX95209.1 - 0.81 9.1 2.9 13 5.2 0.2 2.4 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain LRR_5 PF13306.6 EAX95210.1 - 1.7e-12 47.4 18.4 1.9e-08 34.3 7.9 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95210.1 - 0.096 12.5 7.1 0.57 10.0 0.2 4.0 4 1 1 5 5 5 0 Leucine rich repeat LRR_5 PF13306.6 EAX95211.1 - 2e-106 351.1 86.1 1.2e-28 99.7 2.0 6.2 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95211.1 - 8.4e-16 57.5 18.9 0.085 12.6 0.0 10.4 8 4 6 14 14 14 11 Leucine rich repeat LRR_1 PF00560.33 EAX95211.1 - 0.19 12.4 11.6 1.6 9.6 0.3 6.4 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 EAX95212.1 - 7.7e-58 195.9 0.1 1.1e-57 195.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95212.1 - 1.9e-40 138.8 0.0 2.6e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95212.1 - 3.7e-05 23.2 0.1 0.005 16.2 0.0 2.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EAX95212.1 - 0.00027 20.9 0.0 0.0011 19.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX95212.1 - 0.00044 19.1 0.1 0.00097 18.0 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX95212.1 - 0.0017 17.9 0.6 0.0028 17.3 0.6 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAX95212.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX95212.1 - 0.024 14.2 0.6 0.051 13.1 0.4 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EAX95212.1 - 0.031 13.2 0.2 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 EAX95212.1 - 0.096 12.3 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Atrophin-1 PF03154.15 EAX95213.1 - 2.3 6.4 8.0 2.3 6.4 8.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_S49_N PF08496.10 EAX95213.1 - 4.3 7.4 8.3 4.9 7.2 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mem_trans PF03547.18 EAX95214.1 - 2.9e-18 65.4 30.5 3e-18 65.4 9.6 2.1 1 1 1 2 2 2 2 Membrane transport protein DUF4027 PF13219.6 EAX95214.1 - 0.15 11.9 1.6 0.44 10.5 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Arm_vescicular PF18770.1 EAX95215.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor PP2C PF00481.21 EAX95216.1 - 2.8e-39 135.3 0.0 5.1e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAX95216.1 - 2.7e-25 87.9 66.9 2.7e-08 33.5 0.5 10.7 7 3 3 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EAX95216.1 - 6.3e-25 86.8 83.7 0.00041 20.7 4.5 12.6 6 2 8 14 14 14 11 Leucine Rich repeats (2 copies) PP2C_2 PF13672.6 EAX95216.1 - 9.3e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 EAX95216.1 - 0.16 12.6 70.9 0.55 11.0 0.4 15.2 11 4 1 12 12 12 0 Leucine Rich Repeat CAS_C PF12026.8 EAX95217.1 - 0.39 10.8 12.2 0.053 13.6 4.4 2.1 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain Ank_4 PF13637.6 EAX95219.1 - 7.3e-77 252.8 12.7 6.2e-10 39.4 0.1 13.5 5 4 9 14 14 14 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95219.1 - 2.3e-71 236.4 24.8 6.5e-14 52.3 1.6 8.3 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95219.1 - 9.6e-67 220.2 18.6 2.7e-09 37.1 0.2 11.9 5 2 8 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95219.1 - 4e-51 165.0 16.9 7.8e-05 22.8 0.1 16.6 17 0 0 17 17 17 11 Ankyrin repeat Ank PF00023.30 EAX95219.1 - 4.3e-45 150.2 22.0 0.006 17.0 0.0 15.0 15 1 0 15 15 15 11 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX95219.1 - 1.1e-10 41.2 15.1 2e-10 40.3 15.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX95219.1 - 3.1e-06 26.9 13.2 6.4e-06 25.9 13.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3447 PF11929.8 EAX95219.1 - 0.0079 16.1 11.9 0.88 9.6 0.0 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) zf-RING_5 PF14634.6 EAX95219.1 - 0.013 15.4 14.8 0.027 14.4 14.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EAX95219.1 - 0.065 13.6 15.2 0.12 12.7 15.2 1.5 1 0 0 1 1 1 0 Ring finger domain Ldh_1_N PF00056.23 EAX95220.1 - 2.2e-28 99.1 0.0 3.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX95220.1 - 6.6e-21 75.0 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX95220.1 - 0.0085 16.3 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor of hyc and hyp operons Ldh_1_N PF00056.23 EAX95221.1 - 2.3e-28 99.1 0.0 3.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAX95221.1 - 1e-20 74.4 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX95221.1 - 0.0087 16.3 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor of hyc and hyp operons NDUFB10 PF10249.9 EAX95222.1 - 0.12 12.9 0.6 6.8 7.2 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 GPS2_interact PF15784.5 EAX95224.1 - 0.031 14.7 0.3 0.036 14.5 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX95225.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX95225.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX95226.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX95227.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX95227.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX95228.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX95230.1 - 6.3e-156 517.0 11.7 7.8e-156 516.7 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX95230.1 - 0.87 10.1 5.6 8.6 6.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX95231.1 - 1.4e-06 28.1 1.0 1.9e-06 27.7 0.1 1.7 2 1 0 2 2 2 1 KilA-N domain PSP PF04046.16 EAX95232.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX95233.1 - 1.5e-68 231.0 0.0 1.8e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95233.1 - 7e-38 130.4 0.0 1.7e-37 129.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95233.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX95233.1 - 0.00016 20.7 0.0 0.0003 19.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX95233.1 - 0.0056 16.6 0.0 0.026 14.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX95233.1 - 0.035 12.9 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX95233.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX95233.1 - 0.098 12.3 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 EAX95234.1 - 2e-10 40.2 0.7 2.1e-10 40.1 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Asp PF00026.23 EAX95235.1 - 4.4e-86 289.2 0.2 5.5e-86 288.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAX95235.1 - 1.9e-11 44.6 3.7 2.2e-08 34.5 1.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAX95235.1 - 0.012 16.3 0.0 2.7 8.7 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Radical_SAM PF04055.21 EAX95236.1 - 2.2e-16 60.7 2.3 2.5e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily Fer4_12 PF13353.6 EAX95236.1 - 2.4e-09 37.6 2.0 8.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EAX95236.1 - 8.1e-05 22.7 0.7 0.003 17.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Prismane PF03063.20 EAX95237.1 - 4.9e-161 536.9 0.0 5.5e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family DUF2318 PF10080.9 EAX95237.1 - 0.048 13.8 2.2 0.098 12.8 2.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) FERM_M PF00373.18 EAX95238.1 - 2.1e-24 86.2 5.0 2.3e-11 44.1 0.1 3.8 3 0 0 3 3 3 3 FERM central domain FERM_N PF09379.10 EAX95238.1 - 8e-07 28.9 3.6 2.6 8.0 0.0 7.2 7 0 0 7 7 7 2 FERM N-terminal domain AP3B1_C PF14796.6 EAX95238.1 - 0.034 14.4 0.4 0.13 12.5 0.1 2.1 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal TUG-UBL1 PF11470.8 EAX95238.1 - 0.035 14.3 1.1 8 6.8 0.0 3.9 5 0 0 5 5 5 0 TUG ubiquitin-like domain Ank_2 PF12796.7 EAX95239.1 - 1.3e-07 32.1 0.1 0.0056 17.2 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95239.1 - 3e-07 30.6 0.0 0.038 14.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95239.1 - 1.5e-06 28.0 0.8 8.1 7.4 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAX95239.1 - 0.009 16.6 0.5 33 5.2 0.0 3.7 2 2 0 3 3 3 0 Ankyrin repeats (many copies) Tae4 PF14113.6 EAX95239.1 - 0.029 14.6 0.2 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 Ank PF00023.30 EAX95239.1 - 0.035 14.6 0.0 29 5.3 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat DUF846 PF05832.12 EAX95240.1 - 9.4e-20 71.1 16.4 1.1e-19 70.8 16.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3899 PF13038.6 EAX95240.1 - 0.02 15.4 3.7 0.077 13.5 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) RHH_8 PF17723.1 EAX95240.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family DUF3043 PF11241.8 EAX95240.1 - 0.26 11.3 3.0 2.9 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4191 PF13829.6 EAX95240.1 - 0.38 10.0 3.0 0.24 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TMEM208_SND2 PF05620.11 EAX95240.1 - 1.4 8.7 7.7 1.7 8.4 0.5 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2207 PF09972.9 EAX95240.1 - 2.9 6.5 10.5 63 2.2 10.5 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pecanex_C PF05041.15 EAX95241.1 - 1.1e-12 48.1 0.2 5e-12 45.9 0.0 2.1 2 1 0 2 2 2 1 Pecanex protein (C-terminus) Myb_DNA-binding PF00249.31 EAX95242.1 - 2.2e-28 98.2 2.4 1.5e-14 53.9 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95242.1 - 8.4e-23 80.4 2.9 2.4e-15 56.5 0.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95242.1 - 1.9e-06 27.9 1.8 0.0097 15.9 0.0 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95242.1 - 6.3e-06 26.0 2.4 0.00019 21.3 0.3 2.8 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX95242.1 - 0.002 18.3 0.5 0.0051 17.0 0.3 1.8 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF4085 PF13315.6 EAX95242.1 - 0.032 13.9 1.0 0.18 11.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Myb_DNA-bind_2 PF08914.11 EAX95242.1 - 0.056 13.6 0.2 1.4 9.1 0.0 2.6 1 1 1 2 2 2 0 Rap1 Myb domain HDAC4_Gln PF12203.8 EAX95242.1 - 0.065 13.4 0.4 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 DAO_C PF16901.5 EAX95242.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.6 1 1 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DDR PF08841.10 EAX95244.1 - 0.13 11.3 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX95245.1 - 0.12 12.4 10.2 0.17 11.8 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 EAX95245.1 - 0.34 8.5 14.5 0.43 8.2 14.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MGC-24 PF05283.11 EAX95245.1 - 8.9 6.8 8.2 14 6.2 8.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3839 PF12943.7 EAX95246.1 - 5.1e-157 520.5 13.2 6.3e-157 520.2 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX95246.1 - 0.38 11.3 4.1 4.8 7.7 0.3 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX95246.1 - 1.9 8.8 6.3 12 6.3 0.1 3.8 3 2 2 5 5 5 0 Tup N-terminal T5orf172 PF10544.9 EAX95247.1 - 1.8e-06 28.4 0.0 4.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX95247.1 - 0.013 15.4 1.7 0.069 13.0 0.7 2.4 2 1 0 2 2 2 0 KilA-N domain La PF05383.17 EAX95248.1 - 0.072 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 La domain DUF4378 PF14309.6 EAX95248.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) LRR_5 PF13306.6 EAX95249.1 - 5.6e-22 78.1 35.8 2e-18 66.6 16.9 3.8 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95249.1 - 6.8e-12 45.0 5.8 1.1e-07 31.5 0.1 4.6 1 1 7 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 EAX95249.1 - 0.00083 19.7 21.4 0.016 15.6 0.2 5.0 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) DUF1236 PF06823.12 EAX95249.1 - 0.051 13.5 0.4 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Pentapeptide_4 PF13599.6 EAX95249.1 - 0.28 11.4 14.4 1.8 8.8 0.7 4.3 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) SKN1 PF03935.15 EAX95250.1 - 0.1 11.0 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) PX PF00787.24 EAX95251.1 - 2.7e-08 33.8 0.2 3.6e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 PX domain Thioredoxin_6 PF13848.6 EAX95252.1 - 0.0017 18.3 4.8 0.0039 17.1 1.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain HTH_56 PF18662.1 EAX95252.1 - 0.18 11.9 3.7 5 7.2 0.0 3.4 3 0 0 3 3 3 0 Cch helix turn helix domain His_Phos_2 PF00328.22 EAX95253.1 - 7.5e-13 48.6 0.0 2.1e-07 30.6 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Myb_DNA-binding PF00249.31 EAX95254.1 - 2.2e-33 114.2 1.9 8.3e-16 57.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95254.1 - 8.4e-26 90.0 7.9 7.2e-17 61.4 1.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95254.1 - 1.8e-05 24.7 2.3 0.69 10.0 0.6 3.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX95254.1 - 0.00034 20.7 1.8 0.12 12.6 0.1 3.2 2 1 1 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX95254.1 - 0.00063 19.6 3.3 0.015 15.2 0.9 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX95254.1 - 0.0019 18.6 9.0 0.018 15.4 0.3 2.5 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain PseudoU_synth_1 PF01416.20 EAX95254.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.4 1 1 0 1 1 1 0 tRNA pseudouridine synthase Skp1 PF01466.19 EAX95254.1 - 0.033 14.3 1.6 7.8 6.7 0.0 3.2 3 1 0 3 3 3 0 Skp1 family, dimerisation domain Ank_2 PF12796.7 EAX95255.1 - 2e-07 31.5 0.5 6e-07 30.0 0.3 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95255.1 - 2.1e-07 31.3 0.8 0.00039 20.9 0.2 4.2 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95255.1 - 0.00031 21.0 0.1 1.1 10.1 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX95255.1 - 0.001 19.3 0.1 0.46 10.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BACK PF07707.15 EAX95255.1 - 0.0059 16.7 0.3 0.015 15.4 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank PF00023.30 EAX95255.1 - 0.011 16.1 0.7 0.8 10.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DUF1640 PF07798.11 EAX95255.1 - 0.069 13.2 1.3 0.13 12.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) MULE PF10551.9 EAX95256.1 - 1.4e-10 41.4 0.4 3.9e-10 40.0 0.4 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX95256.1 - 0.025 13.5 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Peptidase_C39_2 PF13529.6 EAX95257.1 - 2.2e-10 41.3 0.1 4.8e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EAX95257.1 - 6.9e-08 32.6 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 EAX95257.1 - 3.9e-05 23.2 0.7 6e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase_C39 like family Phytochelatin PF05023.14 EAX95257.1 - 0.00029 20.1 0.0 0.00051 19.3 0.0 1.4 1 1 0 1 1 1 1 Phytochelatin synthase Guanylate_cyc_2 PF09778.9 EAX95257.1 - 0.00074 18.9 0.0 0.31 10.4 0.0 2.3 1 1 1 2 2 2 2 Guanylylate cyclase Peptidase_C39 PF03412.15 EAX95257.1 - 0.037 13.8 0.1 0.096 12.5 0.0 1.8 2 1 0 2 2 2 0 Peptidase C39 family UBA_6 PF18039.1 EAX95257.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain MKLP1_Arf_bdg PF16540.5 EAX95258.1 - 0.12 12.4 1.9 0.18 11.9 0.1 2.1 2 1 0 3 3 3 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Peptidase_C97 PF05903.14 EAX95259.1 - 8.3e-15 54.9 0.5 9.9e-15 54.7 0.5 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 EAX95259.1 - 0.00015 21.4 0.9 0.00017 21.2 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4796) LRAT PF04970.13 EAX95259.1 - 0.12 12.7 0.4 0.26 11.6 0.2 1.7 1 1 0 1 1 1 0 Lecithin retinol acyltransferase Macro PF01661.21 EAX95260.1 - 2.2e-09 37.4 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Macro domain IBD PF10416.9 EAX95261.1 - 6.7e-18 64.9 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD TMPIT PF07851.13 EAX95262.1 - 1.6 7.9 7.0 2.2 7.4 7.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EAX95262.1 - 2.2 7.1 7.9 2.7 6.8 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EAX95262.1 - 5.4 6.3 13.8 5.2 6.3 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHIPPO-rpt PF07004.12 EAX95263.1 - 0.0019 19.0 4.6 0.53 11.3 0.3 3.7 4 0 0 4 4 4 2 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 EAX95264.1 - 7.8e-07 29.7 23.8 0.69 10.9 0.2 5.5 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat Gly-zipper_Omp PF13488.6 EAX95266.1 - 0.0072 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX95266.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX95266.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX95266.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif TMP PF05017.14 EAX95266.1 - 3 8.9 0.2 3 8.9 0.2 3.3 4 0 0 4 4 4 0 TMP repeat Pox_A32 PF04665.12 EAX95268.1 - 7.6e-05 22.3 3.5 0.00014 21.5 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX95268.1 - 0.0046 17.0 0.8 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX95268.1 - 0.0089 15.6 0.2 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX95268.1 - 0.051 12.8 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Mito_carr PF00153.27 EAX95270.1 - 6.2e-64 212.0 2.7 1.3e-23 82.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5538 PF17692.1 EAX95270.1 - 0.1 12.6 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Ras PF00071.22 EAX95271.1 - 4.8e-57 192.1 0.4 5.6e-57 191.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95271.1 - 5.3e-33 113.8 0.1 7.4e-33 113.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95271.1 - 1.3e-16 60.6 0.0 1.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX95271.1 - 1.7e-05 24.8 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX95271.1 - 3.1e-05 24.0 0.0 4.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX95271.1 - 0.00053 19.4 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAX95271.1 - 0.00056 19.5 0.1 0.0025 17.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX95271.1 - 0.00074 19.0 0.0 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EAX95271.1 - 0.0075 16.1 0.2 0.092 12.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EAX95271.1 - 0.0075 16.4 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX95271.1 - 0.0084 16.4 0.1 0.04 14.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX95271.1 - 0.011 16.1 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EAX95271.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAX95271.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EAX95271.1 - 0.036 13.3 0.1 0.077 12.3 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EAX95271.1 - 0.045 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EAX95271.1 - 0.052 12.9 0.7 0.55 9.5 0.0 2.3 2 1 0 2 2 2 0 KaiC AAA_25 PF13481.6 EAX95271.1 - 0.076 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 EAX95271.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 EAX95271.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TcpA PF05946.12 EAX95271.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA DUF3447 PF11929.8 EAX95272.1 - 4.7e-32 109.8 6.3 4.7e-32 109.8 6.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX95272.1 - 3.4e-06 27.5 2.4 0.00049 20.6 0.1 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95272.1 - 0.00013 22.4 1.0 0.29 11.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95272.1 - 0.0037 17.6 1.4 26 5.8 0.0 5.1 5 1 2 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 EAX95272.1 - 0.045 14.1 0.8 1.9 8.9 0.0 3.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 EAX95272.1 - 0.047 14.1 0.0 5.9 7.5 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat RL PF17797.1 EAX95272.1 - 0.94 9.5 3.5 19 5.3 0.1 3.3 3 0 0 3 3 3 0 RL domain Peptidase_S28 PF05577.12 EAX95273.1 - 2.4e-24 85.9 3.1 3.1e-24 85.6 3.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF4750 PF15938.5 EAX95273.1 - 0.23 11.1 1.1 0.46 10.2 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) EGF_2 PF07974.13 EAX95273.1 - 0.28 11.6 9.5 0.56 10.6 9.5 1.5 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.32 EAX95274.1 - 9.9e-23 80.0 9.7 1.7e-07 31.8 0.5 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95274.1 - 2.5e-13 50.2 0.0 5.9e-08 32.9 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EAX95274.1 - 2.2e-05 23.2 0.2 0.0077 14.8 0.1 1.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 EAX95274.1 - 0.0013 17.4 0.4 1.1 7.8 0.0 3.3 2 2 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 EAX95274.1 - 0.0079 16.1 0.4 2 8.4 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PixA PF12306.8 EAX95274.1 - 0.038 14.2 2.6 0.05 13.8 1.0 2.0 2 0 0 2 2 2 0 Inclusion body protein WD40_like PF17005.5 EAX95274.1 - 0.039 13.3 5.6 0.01 15.2 2.0 1.9 2 1 0 2 2 2 0 WD40-like domain zf-C4H2 PF10146.9 EAX95274.1 - 0.11 12.7 3.6 0.2 11.9 3.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Lsm_interact PF05391.11 EAX95274.1 - 0.29 10.7 0.8 0.74 9.4 0.8 1.7 1 0 0 1 1 1 0 Lsm interaction motif MOR2-PAG1_N PF14222.6 EAX95275.1 - 1.6e-06 27.4 0.4 1.6e-06 27.4 0.4 1.6 2 0 0 2 2 2 1 Cell morphogenesis N-terminal Pkinase PF00069.25 EAX95276.1 - 5.8e-69 232.4 0.0 7.4e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95276.1 - 5.7e-36 124.1 0.0 8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95276.1 - 1.3e-11 44.4 0.1 2.5e-08 33.6 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAX95276.1 - 0.00053 18.9 0.0 0.0012 17.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 EAX95276.1 - 0.001 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.23 EAX95276.1 - 0.0018 18.2 0.0 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 EAX95276.1 - 0.0032 18.1 1.7 0.0081 16.8 1.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EAX95276.1 - 0.02 14.3 0.2 0.035 13.5 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX95276.1 - 0.043 12.7 0.0 0.091 11.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Beach PF02138.18 EAX95277.1 - 2.9e-98 328.7 0.0 5.4e-98 327.8 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX95277.1 - 1.4e-08 34.3 0.8 9.2e-08 31.7 0.8 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 EAX95277.1 - 1.7e-07 30.8 0.2 4.4e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 EAX95277.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EAX95277.1 - 0.022 14.9 0.2 0.22 11.6 0.2 2.6 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH KilA-N PF04383.13 EAX95278.1 - 2.4e-23 82.1 0.2 4.6e-23 81.2 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX95278.1 - 0.31 10.4 0.7 1.2 8.5 0.3 2.1 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Glyco_transf_49 PF13896.6 EAX95279.1 - 0.019 14.3 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan EpuA PF11772.8 EAX95279.1 - 0.17 11.6 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DUF4795 PF16043.5 EAX95279.1 - 0.48 10.0 5.1 4.1 7.0 5.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX95279.1 - 0.6 10.2 10.9 0.22 11.6 3.4 3.4 3 1 0 3 3 3 0 Phage tail repeat like YmaF PF12788.7 EAX95279.1 - 1.5 9.4 5.7 14 6.3 0.2 3.4 2 1 0 3 3 3 0 YmaF family Phage_fiber PF03335.13 EAX95279.1 - 3.9 7.9 13.7 0.5 10.7 1.9 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat DUF5365 PF17326.2 EAX95280.1 - 0.019 15.4 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF2931 PF11153.8 EAX95281.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2931) S1FA PF04689.13 EAX95281.1 - 0.11 12.7 0.4 0.14 12.3 0.4 1.1 1 0 0 1 1 1 0 DNA binding protein S1FA EphA2_TM PF14575.6 EAX95281.1 - 0.11 13.4 0.0 0.12 13.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_6 PF13964.6 EAX95283.1 - 1.4e-18 66.5 9.4 0.00047 20.3 0.3 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EAX95283.1 - 7.2e-18 64.3 6.5 0.00035 20.5 0.1 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EAX95283.1 - 3.1e-16 59.2 3.1 0.00015 21.9 0.0 4.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX95283.1 - 4.8e-11 42.1 11.5 0.0003 20.3 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 EAX95283.1 - 3.9e-10 39.5 8.5 0.055 13.5 0.2 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAX95283.1 - 2.3e-08 33.7 10.4 0.0096 15.9 0.1 5.4 5 0 0 5 5 5 2 Kelch motif PQQ PF01011.21 EAX95283.1 - 0.048 13.6 0.0 23 5.2 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Acetyltransf_1 PF00583.25 EAX95284.1 - 3.6e-14 53.0 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAX95284.1 - 3.7e-14 52.8 0.1 4.4e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX95284.1 - 3.1e-10 40.4 0.2 4.8e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX95284.1 - 5e-08 32.8 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EAX95284.1 - 6.9e-06 26.3 0.3 1e-05 25.7 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EAX95284.1 - 0.0006 19.3 3.5 0.0018 17.8 3.5 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase PAN_3 PF08277.12 EAX95285.1 - 0.18 11.7 6.0 0.046 13.5 1.7 2.3 2 0 0 2 2 2 0 PAN-like domain UBA PF00627.31 EAX95286.1 - 2.6e-10 40.0 0.8 1e-06 28.5 0.3 2.4 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 EAX95286.1 - 1.9e-06 27.6 0.3 6e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAX95286.1 - 1.9e-05 24.3 0.1 7.6e-05 22.4 0.1 2.1 3 0 0 3 3 3 1 Ubiquitin family CUE PF02845.16 EAX95286.1 - 0.00044 19.9 0.1 0.11 12.2 0.1 2.7 2 0 0 2 2 2 1 CUE domain XPC-binding PF09280.11 EAX95286.1 - 0.0013 18.4 6.3 0.0013 18.4 6.3 2.4 2 1 1 3 3 3 1 XPC-binding domain RuvA_C PF07499.13 EAX95286.1 - 0.021 15.3 1.1 0.052 14.0 1.1 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain Glyco_transf_88 PF16849.5 EAX95286.1 - 0.054 12.4 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 DUF1296 PF06972.11 EAX95286.1 - 0.083 13.0 0.6 0.45 10.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) RPN13_C PF16550.5 EAX95286.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.6 3 0 0 3 3 3 0 UCH-binding domain DUF5578 PF17741.1 EAX95287.1 - 3e-21 76.1 0.5 4.3e-21 75.5 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) GRIP PF01465.20 EAX95287.1 - 0.11 12.4 0.0 0.4 10.6 0.0 2.0 1 0 0 1 1 1 0 GRIP domain GlcNAc_2-epim PF07221.11 EAX95288.1 - 1.3e-43 149.5 3.7 3.3e-43 148.3 3.8 1.5 1 1 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 EAX95288.1 - 0.00049 19.7 4.7 0.16 11.5 2.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 EAX95288.1 - 0.0026 17.3 0.8 0.48 9.9 0.1 3.0 3 0 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Histone PF00125.24 EAX95289.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX95289.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX95289.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX95289.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein NUDIX PF00293.28 EAX95291.1 - 1.1e-14 54.6 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 EAX95291.1 - 6.4e-08 32.8 0.8 9.3e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 Dcp2, box A domain DnaJ_C PF01556.18 EAX95292.1 - 4.4e-28 98.2 1.4 6.3e-28 97.7 1.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX95292.1 - 7e-22 77.3 1.3 1.5e-21 76.3 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain WD40_like PF17005.5 EAX95294.1 - 0.00044 19.7 1.8 0.0023 17.3 0.9 2.3 1 1 1 2 2 2 1 WD40-like domain WD40 PF00400.32 EAX95294.1 - 0.2 12.6 0.4 4 8.5 0.3 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Abdominal-A PF12407.8 EAX95294.1 - 2.5 7.8 10.6 4.4 7.0 2.4 2.4 2 0 0 2 2 2 0 Homeobox protein LRR_5 PF13306.6 EAX95295.1 - 2.9e-46 156.6 65.7 5.2e-19 68.5 10.2 4.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX95296.1 - 3.2e-21 75.6 6.8 8.7e-21 74.2 4.7 2.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Sigma_reg_N PF13800.6 EAX95296.1 - 0.026 14.8 0.9 0.052 13.8 0.9 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal LRR_8 PF13855.6 EAX95296.1 - 0.027 14.2 2.5 1.1 9.1 0.1 3.3 2 1 1 3 3 3 0 Leucine rich repeat Orf78 PF06024.12 EAX95296.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 EAX95297.1 - 0.0018 17.1 0.4 0.002 17.0 0.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MSC PF09402.10 EAX95297.1 - 0.0062 16.0 0.6 0.0069 15.9 0.6 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Histone PF00125.24 EAX95298.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX95298.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX95298.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX95298.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAX95299.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX95299.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX95299.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX95299.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX95299.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX95299.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX95299.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX95299.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) LRR_5 PF13306.6 EAX95300.1 - 1.3e-11 44.5 2.1 1.7e-11 44.2 2.1 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95300.1 - 3.8e-06 26.6 0.8 6.4e-06 25.8 0.8 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EAX95300.1 - 0.0043 17.4 0.9 0.01 16.3 0.9 1.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX95301.1 - 5.7e-58 194.4 31.3 5.3e-28 97.5 4.1 2.8 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95301.1 - 2.3e-08 33.7 0.0 0.012 15.3 0.0 4.2 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EAX95301.1 - 0.00023 21.5 0.6 1.3 9.6 0.0 4.0 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) Furin-like PF00757.20 EAX95301.1 - 0.084 12.7 3.8 0.67 9.8 0.3 2.2 2 0 0 2 2 2 0 Furin-like cysteine rich region zf-Tim10_DDP PF02953.15 EAX95301.1 - 0.12 12.0 4.9 0.5 10.1 0.6 3.1 3 1 0 3 3 3 0 Tim10/DDP family zinc finger DUF1699 PF08004.11 EAX95301.1 - 0.14 11.8 1.0 13 5.4 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) Beach PF02138.18 EAX95302.1 - 6.1e-06 25.8 1.2 0.00089 18.7 0.1 3.4 2 1 1 3 3 3 2 Beige/BEACH domain zf-UBP PF02148.19 EAX95302.1 - 9.3 6.7 9.1 23 5.4 9.1 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein IBD PF10416.9 EAX95303.1 - 2.4e-18 66.4 0.2 4.7e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4106 PF13388.6 EAX95304.1 - 2.8e-268 889.9 20.1 2.8e-268 889.9 20.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX95304.1 - 0.09 13.1 2.0 1.5 9.2 0.2 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated Pkinase PF00069.25 EAX95306.1 - 3.6e-50 170.8 0.0 5e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95306.1 - 3.1e-26 92.2 0.0 4e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95306.1 - 4.7e-05 22.8 0.0 0.00012 21.5 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX95306.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EAX95306.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX95306.1 - 0.038 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX95306.1 - 0.09 11.7 0.0 4.3 6.2 0.0 2.1 1 1 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX95306.1 - 0.17 10.6 0.0 8.5 5.0 0.0 2.0 1 1 1 2 2 2 0 Fungal protein kinase HSCB_C PF07743.13 EAX95307.1 - 7.6e-15 55.2 0.9 1.7e-14 54.1 0.9 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EAX95307.1 - 0.00016 21.8 1.2 0.0004 20.4 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain Hydrolase_4 PF12146.8 EAX95308.1 - 1.6e-31 109.4 0.0 1.9e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX95308.1 - 4e-08 34.1 0.0 5.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAX95308.1 - 5.5e-07 29.5 0.8 1.4e-06 28.2 0.3 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAX95308.1 - 0.0065 16.0 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EAX95308.1 - 0.0096 15.6 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 EAX95308.1 - 0.0099 15.7 0.0 5.1 6.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EAX95308.1 - 0.022 14.6 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) PAF-AH_p_II PF03403.13 EAX95308.1 - 0.18 10.3 0.6 6.3 5.2 0.2 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Paf1 PF03985.13 EAX95309.1 - 0.12 11.4 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Paf1 Ank_2 PF12796.7 EAX95310.1 - 2.6e-57 191.4 1.3 2e-21 76.3 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95310.1 - 7.8e-33 111.5 0.0 3e-05 24.3 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EAX95310.1 - 5.9e-32 109.6 0.0 8.9e-11 42.1 0.0 4.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95310.1 - 4.4e-27 93.8 0.0 9.2e-08 32.2 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95310.1 - 1.7e-21 74.0 0.0 0.0047 17.3 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat DUF3083 PF11281.8 EAX95310.1 - 0.00076 18.9 0.1 1.1 8.6 0.0 2.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3083) DUF1897 PF09005.10 EAX95310.1 - 0.067 12.7 0.0 74 2.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) PAP2_C PF14360.6 EAX95311.1 - 4.6e-18 65.5 7.0 4.6e-18 65.5 7.0 3.0 3 1 0 3 3 3 1 PAP2 superfamily C-terminal DsbB PF02600.16 EAX95311.1 - 0.048 14.1 0.9 3.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Disulfide bond formation protein DsbB PAP2 PF01569.21 EAX95311.1 - 0.12 12.1 10.8 0.13 12.0 9.0 2.1 1 1 0 1 1 1 0 PAP2 superfamily Claudin_2 PF13903.6 EAX95311.1 - 0.79 9.4 6.9 2.2 8.0 0.1 2.9 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Thioredoxin PF00085.20 EAX95312.1 - 5.6e-12 45.6 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EAX95312.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin SNARE PF05739.19 EAX95313.1 - 3e-12 46.3 0.6 8.1e-12 45.0 0.6 1.8 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EAX95313.1 - 8.7e-08 32.2 14.0 1.1e-07 31.8 14.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 PepSY_TM PF03929.16 EAX95313.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Prominin PF05478.11 EAX95313.1 - 0.036 12.0 18.3 0.12 10.3 5.3 2.3 1 1 1 2 2 2 0 Prominin YscO-like PF16789.5 EAX95313.1 - 0.04 13.9 26.9 0.039 14.0 22.9 2.4 1 1 0 2 2 2 0 YscO-like protein V_ATPase_I PF01496.19 EAX95313.1 - 0.061 11.2 16.5 0.0072 14.3 12.3 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 EAX95313.1 - 0.083 11.4 0.6 0.14 10.7 0.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 EAX95313.1 - 0.13 12.4 28.3 0.32 11.2 28.4 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) T2SSF PF00482.23 EAX95313.1 - 0.18 11.8 1.0 0.3 11.0 0.2 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF1664 PF07889.12 EAX95313.1 - 0.36 10.9 17.6 3 7.9 3.8 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FtsX PF02687.21 EAX95313.1 - 0.61 10.6 3.7 0.89 10.1 3.7 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF4201 PF13870.6 EAX95313.1 - 0.86 9.3 23.1 0.042 13.6 10.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) CENP-N PF05238.13 EAX95313.1 - 1.2 8.4 10.6 1.4 8.1 10.6 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CHD5 PF04420.14 EAX95313.1 - 1.2 9.0 7.6 16 5.3 4.7 2.8 1 1 2 3 3 3 0 CHD5-like protein DUF2207 PF09972.9 EAX95313.1 - 1.3 7.7 5.4 0.44 9.2 0.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) UPF0258 PF06789.12 EAX95313.1 - 2 8.5 5.9 4.1 7.5 5.6 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) ABC2_membrane_3 PF12698.7 EAX95313.1 - 2.2 7.3 4.9 2.9 6.9 4.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 EAX95313.1 - 2.3 7.4 8.0 4.6 6.4 8.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter DUF2730 PF10805.8 EAX95313.1 - 3.5 7.8 7.1 1.5 9.0 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 EAX95313.1 - 4 6.0 24.7 5.2 5.6 24.7 1.0 1 0 0 1 1 1 0 AAA domain Fibin PF15819.5 EAX95313.1 - 4.1 7.1 13.9 0.28 10.9 2.9 2.2 1 1 1 2 2 2 0 Fin bud initiation factor homologue UPF0242 PF06785.11 EAX95313.1 - 4.9 7.2 27.3 23 5.0 12.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YjbH PF06082.11 EAX95313.1 - 5.1 5.8 10.2 6.1 5.5 10.2 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4407 PF14362.6 EAX95313.1 - 5.5 6.2 27.5 7.5 5.8 26.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CNDH2_C PF16858.5 EAX95313.1 - 6 6.6 18.7 8.3 6.2 18.7 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2721 PF11026.8 EAX95313.1 - 9.1 6.2 10.8 1.6 8.7 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Atg14 PF10186.9 EAX95313.1 - 9.1 5.3 22.9 2 7.4 17.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Orf78 PF06024.12 EAX95313.1 - 9.8 6.5 16.9 1.7e+02 2.6 11.3 2.9 2 1 0 2 2 2 0 Orf78 (ac78) PSP PF04046.16 EAX95314.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95315.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2362 PF10154.9 EAX95317.1 - 0.0013 17.8 2.9 0.0018 17.3 2.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF3794 PF12673.7 EAX95318.1 - 0.024 14.9 9.0 5.6 7.3 0.1 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF3794) DUF5011 PF16403.5 EAX95318.1 - 0.056 13.6 4.4 3.2 7.9 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Top6b_C PF18000.1 EAX95318.1 - 0.083 13.1 0.8 25 5.1 0.1 3.3 2 1 1 3 3 3 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain YolD PF08863.10 EAX95318.1 - 1.7 8.8 7.8 16 5.6 0.8 3.4 2 0 0 2 2 2 0 YolD-like protein DUF4982 PF16355.5 EAX95319.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Big_7 PF17957.1 EAX95319.1 - 0.0074 17.0 1.1 1.5 9.6 0.1 2.8 2 1 0 2 2 2 2 Bacterial Ig domain Pik1 PF11522.8 EAX95320.1 - 0.1 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Membrane_bind PF14564.6 EAX95320.1 - 0.12 12.8 2.6 0.17 12.3 0.3 2.4 2 1 0 2 2 2 0 Membrane binding Rhodanese PF00581.20 EAX95320.1 - 0.16 12.5 0.5 34 5.0 0.1 2.9 3 0 0 3 3 3 0 Rhodanese-like domain DUF4064 PF13273.6 EAX95321.1 - 0.015 15.6 0.1 2.5 8.4 0.1 5.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) KilA-N PF04383.13 EAX95323.1 - 4.1e-22 78.2 0.2 8.1e-22 77.2 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX95323.1 - 0.081 12.9 1.1 0.27 11.2 0.0 2.3 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3839 PF12943.7 EAX95324.1 - 1.2e-156 519.3 14.0 1.5e-156 519.0 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX95324.1 - 0.11 12.7 0.2 2.7 8.3 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX95324.1 - 0.9 10.0 6.1 4.8 7.7 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Podoplanin PF05808.11 EAX95325.1 - 9.8e-05 22.5 0.9 0.00034 20.7 0.6 2.1 1 1 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAX95325.1 - 0.00026 21.2 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 EAX95325.1 - 0.0013 18.7 2.0 0.0013 18.7 2.0 2.6 1 1 0 2 2 2 1 TMEM154 protein family DUF4064 PF13273.6 EAX95325.1 - 0.0018 18.5 0.1 0.0066 16.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1180 PF06679.12 EAX95325.1 - 0.0021 18.5 0.2 0.0052 17.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF5305 PF17231.2 EAX95325.1 - 0.0041 16.6 0.1 0.0075 15.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) TMEM51 PF15345.6 EAX95325.1 - 0.0078 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Rax2 PF12768.7 EAX95325.1 - 0.015 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2970 PF11174.8 EAX95325.1 - 0.02 14.7 1.2 0.033 14.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) LRR19-TM PF15176.6 EAX95325.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Collectrin PF16959.5 EAX95325.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Renal amino acid transporter DUF3976 PF13121.6 EAX95325.1 - 0.12 12.5 2.5 4 7.7 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) TMEM132D_C PF15706.5 EAX95325.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1461 PF07314.11 EAX95325.1 - 0.42 10.5 2.6 3.9 7.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) RIFIN PF02009.16 EAX95325.1 - 2.9 7.7 5.3 0.53 10.1 0.7 1.9 1 1 1 2 2 2 0 Rifin Orf78 PF06024.12 EAX95327.1 - 6.3e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Podoplanin PF05808.11 EAX95327.1 - 7e-05 23.0 0.6 7e-05 23.0 0.6 1.8 1 1 1 2 2 2 1 Podoplanin DUF1180 PF06679.12 EAX95327.1 - 0.00053 20.5 0.1 0.00088 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF5305 PF17231.2 EAX95327.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DUF4064 PF13273.6 EAX95327.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4064) TMEM51 PF15345.6 EAX95327.1 - 0.0022 17.9 0.4 0.0036 17.2 0.3 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 Rax2 PF12768.7 EAX95327.1 - 0.0054 16.2 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF2970 PF11174.8 EAX95327.1 - 0.0065 16.3 1.2 0.011 15.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) LRR19-TM PF15176.6 EAX95327.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain DUF5383 PF17355.2 EAX95327.1 - 0.014 15.8 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) TMEM154 PF15102.6 EAX95327.1 - 0.019 14.9 10.5 0.064 13.2 10.5 2.1 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 EAX95327.1 - 0.025 13.3 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Collectrin PF16959.5 EAX95327.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter RIFIN PF02009.16 EAX95327.1 - 0.041 13.8 0.2 0.056 13.3 0.2 1.2 1 0 0 1 1 1 0 Rifin TMEM132D_C PF15706.5 EAX95327.1 - 0.053 13.3 0.8 0.12 12.2 0.8 1.7 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Endomucin PF07010.12 EAX95327.1 - 0.1 12.6 11.0 0.17 11.9 11.0 1.3 1 0 0 1 1 1 0 Endomucin DUF5527 PF17665.1 EAX95327.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Ly49 PF08391.10 EAX95327.1 - 0.17 12.3 0.5 0.27 11.6 0.0 1.6 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region MAP17 PF15807.5 EAX95327.1 - 0.2 11.9 2.2 0.21 11.8 0.2 1.9 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 EAX95327.1 - 0.29 12.1 0.3 0.29 12.1 0.3 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_PIX PF03955.14 EAX95327.1 - 1.6 8.9 5.0 3.5 7.8 3.7 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF3672 PF12421.8 EAX95328.1 - 0.07 13.0 1.4 5.2 7.0 1.0 2.5 1 1 1 2 2 2 0 Fibronectin type III protein Guanylate_cyc PF00211.20 EAX95329.1 - 1.1e-42 145.8 0.0 2e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX95329.1 - 1.9e-17 63.4 0.2 5.5e-17 61.9 0.2 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX95329.1 - 3.7e-08 33.4 0.6 1.4e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 EAX95329.1 - 1.5e-05 24.5 0.2 0.00073 19.0 0.2 2.5 2 1 0 2 2 2 1 Heme NO binding associated PAS_4 PF08448.10 EAX95329.1 - 5.1e-05 23.5 0.0 8.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EAX95329.1 - 0.047 14.0 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 EAX95329.1 - 0.17 11.9 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain DUF515 PF04415.12 EAX95331.1 - 0.053 11.9 1.1 0.23 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Guanylate_cyc PF00211.20 EAX95332.1 - 3.4e-41 140.9 0.0 6.8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX95332.1 - 5.9e-15 55.4 1.1 3.1e-14 53.1 0.7 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAX95332.1 - 4.8e-05 23.3 0.1 0.00016 21.6 0.1 1.9 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX95332.1 - 0.003 17.0 0.1 0.003 17.0 0.1 2.0 2 0 0 2 2 2 1 Heme NO binding associated PAS_4 PF08448.10 EAX95332.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Lectin_N PF03954.14 EAX95333.1 - 0.089 12.5 0.2 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MAP17 PF15807.5 EAX95333.1 - 0.14 12.4 0.1 0.42 10.8 0.1 1.8 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ly49 PF08391.10 EAX95333.1 - 1.3 9.4 5.1 0.4 11.1 0.4 2.7 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Gly_rich PF12810.7 EAX95334.1 - 2.5e-35 122.6 32.1 2.8e-35 122.4 32.1 1.0 1 0 0 1 1 1 1 Glycine rich protein MULE PF10551.9 EAX95335.1 - 2.6e-10 40.6 0.1 2.6e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 EAX95335.1 - 0.053 14.2 0.5 0.15 12.8 0.5 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain FLYWCH PF04500.16 EAX95335.1 - 0.16 12.1 5.6 0.31 11.2 5.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain Gly_rich PF12810.7 EAX95336.1 - 1.4e-40 139.7 37.5 1.6e-40 139.6 37.5 1.0 1 0 0 1 1 1 1 Glycine rich protein NBD94 PF16830.5 EAX95337.1 - 0.11 12.9 2.4 4.3 7.8 0.1 2.1 1 1 1 2 2 2 0 Nucleotide-Binding Domain 94 of RH Myb_DNA-binding PF00249.31 EAX95339.1 - 6.2e-30 103.1 0.0 1.5e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95339.1 - 2.8e-23 81.9 1.0 8.8e-17 61.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95339.1 - 2e-06 27.8 0.4 0.068 13.2 0.0 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95339.1 - 8.8e-05 22.3 0.3 0.021 14.7 0.1 2.3 1 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX95339.1 - 0.0029 17.7 0.0 0.75 10.0 0.0 2.8 2 1 0 2 2 2 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAX95339.1 - 0.0098 16.1 0.0 0.034 14.4 0.0 1.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX95339.1 - 0.052 13.9 0.6 1.5 9.2 0.3 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95340.1 - 1.6e-16 60.3 2.5 3.2e-10 40.1 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX95340.1 - 5.4e-16 58.5 0.9 4.3e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX95340.1 - 0.006 16.4 1.8 0.057 13.3 0.5 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX95340.1 - 0.11 12.8 5.2 0.78 10.2 3.4 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX95340.1 - 0.57 10.5 5.5 3.6 8.0 0.5 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HMG_box_2 PF09011.10 EAX95340.1 - 2.9 8.5 5.1 6.7 7.4 0.1 2.8 2 1 1 3 3 3 0 HMG-box domain SpoVS PF04232.12 EAX95341.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Scm3 PF10384.9 EAX95342.1 - 0.083 12.6 0.6 0.31 10.8 0.1 2.2 2 0 0 2 2 2 0 Centromere protein Scm3 60KD_IMP PF02096.20 EAX95342.1 - 0.17 11.8 3.2 0.24 11.3 1.6 1.9 1 1 1 2 2 2 0 60Kd inner membrane protein SAS4 PF15460.6 EAX95342.1 - 6.5 6.9 7.6 4 7.6 0.7 2.9 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 PSP PF04046.16 EAX95343.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95344.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF3839 PF12943.7 EAX95345.1 - 1.3e-58 198.3 3.8 1.5e-58 198.1 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAX95345.1 - 0.048 13.1 0.2 0.052 13.0 0.2 1.0 1 0 0 1 1 1 0 Z1 domain Amidase02_C PF12123.8 EAX95347.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX95348.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX95348.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase SapB_2 PF03489.17 EAX95349.1 - 0.0095 16.0 0.9 0.018 15.1 0.0 2.0 2 1 0 2 2 2 1 Saposin-like type B, region 2 Sec23_trunk PF04811.15 EAX95350.1 - 4e-41 141.2 0.0 6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAX95350.1 - 8.3e-23 80.9 0.0 1.9e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EAX95350.1 - 7.4e-20 70.7 0.1 4.9e-19 68.1 0.0 2.5 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EAX95350.1 - 2e-12 46.9 8.1 4.5e-12 45.8 8.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAX95350.1 - 5.9e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EAX95350.1 - 0.027 13.8 0.4 0.07 12.5 0.4 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EAX95350.1 - 0.033 14.8 0.0 7.5 7.3 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain zinc_ribbon_10 PF10058.9 EAX95350.1 - 0.17 11.7 9.1 0.13 12.0 3.9 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein HEPN_STY4199 PF18729.1 EAX95352.1 - 0.008 15.4 0.0 0.0097 15.1 0.0 1.1 1 0 0 1 1 1 1 STY4199-like HEPN DUF5557 PF17712.1 EAX95352.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5557) DUF3528 PF12045.8 EAX95352.1 - 0.067 13.8 0.0 0.077 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) DUF563 PF04577.14 EAX95353.1 - 2.6e-12 47.3 0.1 3.9e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TPR_10 PF13374.6 EAX95354.1 - 0.053 13.4 0.4 0.053 13.4 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF421 PF04239.12 EAX95354.1 - 0.062 13.1 0.8 0.062 13.1 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF421) Histidinol_dh PF00815.20 EAX95354.1 - 5.5 5.9 8.0 5.2 6.0 0.1 2.7 2 1 0 2 2 2 0 Histidinol dehydrogenase HECT PF00632.25 EAX95355.1 - 4.7e-81 272.6 0.0 7.6e-81 271.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EAX95355.1 - 0.0033 17.6 0.2 0.0077 16.5 0.2 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF4274 PF14096.6 EAX95356.1 - 0.046 13.7 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) Cbl_N2 PF02761.14 EAX95357.1 - 0.0014 19.3 2.1 0.0051 17.5 2.1 2.0 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain LRR_4 PF12799.7 EAX95357.1 - 0.017 15.5 3.6 1.7 9.2 0.7 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) NOP5NT PF08156.13 EAX95357.1 - 0.82 10.1 5.3 1.9 9.0 4.2 2.3 2 0 0 2 2 2 0 NOP5NT (NUC127) domain Pkinase_Tyr PF07714.17 EAX95358.1 - 2.4e-58 197.4 0.0 9.8e-58 195.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95358.1 - 2.3e-56 191.1 0.0 6.9e-56 189.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAX95358.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX95358.1 - 0.00083 18.8 0.4 0.01 15.2 0.1 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MethyltransfD12 PF02086.15 EAX95358.1 - 0.002 17.9 0.4 0.0055 16.4 0.4 1.8 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Pkinase_fungal PF17667.1 EAX95358.1 - 0.015 14.1 0.1 0.028 13.2 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EAX95358.1 - 0.046 13.3 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 RIO1 family DivIC PF04977.15 EAX95359.1 - 2.1 8.2 10.5 0.13 12.1 3.1 2.6 2 1 0 2 2 2 0 Septum formation initiator Ribosomal_L26 PF16906.5 EAX95360.1 - 8.6e-29 99.8 2.5 1.1e-28 99.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EAX95360.1 - 9.1e-06 25.4 0.3 2e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 KOW motif SGS PF05002.15 EAX95361.1 - 2.4e-24 85.2 0.3 5.6e-24 84.1 0.3 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EAX95361.1 - 2.6e-05 25.2 0.7 3.8e-05 24.6 0.7 1.3 1 0 0 1 1 1 1 CS domain DHR10 PF18595.1 EAX95362.1 - 0.005 16.9 0.8 0.005 16.9 0.8 4.4 2 2 1 4 4 4 1 Designed helical repeat protein 10 domain Taxilin PF09728.9 EAX95362.1 - 1.4 8.0 44.6 0.73 8.9 22.5 2.6 1 1 0 2 2 2 0 Myosin-like coiled-coil protein HALZ PF02183.18 EAX95362.1 - 1.8 8.9 10.1 0.35 11.1 1.7 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper FlxA PF14282.6 EAX95362.1 - 2 8.5 54.2 0.14 12.2 12.5 5.0 3 2 2 5 5 5 0 FlxA-like protein ARTD15_N PF18084.1 EAX95362.1 - 3 8.2 5.7 3.7 7.9 0.2 3.2 3 0 0 3 3 3 0 ARTD15 N-terminal domain DUF4407 PF14362.6 EAX95362.1 - 7.9 5.7 29.2 1.8e+04 -8.8 29.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YvrJ PF12841.7 EAX95362.1 - 8.2 6.0 7.0 1.6 8.4 0.2 3.3 3 0 0 3 3 3 0 YvrJ protein family DDE_1 PF03184.19 EAX95364.1 - 2.9e-13 49.9 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease EF-hand_6 PF13405.6 EAX95365.1 - 1.5e-13 49.4 0.6 3.6e-05 23.3 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EAX95365.1 - 3.2e-13 49.9 0.6 2.8e-09 37.3 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX95365.1 - 2.7e-12 45.3 2.8 0.00014 21.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EAX95365.1 - 1.4e-07 31.2 1.2 0.043 13.7 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EAX95365.1 - 1.9e-07 30.2 0.8 0.0032 16.9 0.0 3.7 3 0 0 3 3 3 2 EF hand AlphaC_N PF08829.10 EAX95365.1 - 0.13 12.3 0.0 4.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Alpha C protein N terminal Sugar_tr PF00083.24 EAX95368.1 - 0.076 11.9 0.6 0.13 11.1 0.6 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter FlaC_arch PF05377.11 EAX95368.1 - 2.1 8.8 18.0 1.8 9.0 1.2 5.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Nnf1 PF03980.14 EAX95368.1 - 3 8.2 11.7 6.2 7.2 0.7 3.1 3 0 0 3 3 3 0 Nnf1 DMPK_coil PF08826.10 EAX95368.1 - 3 8.0 13.7 0.9 9.7 2.3 3.9 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF4855 PF16147.5 EAX95368.1 - 4.3 6.3 7.0 0.94 8.5 1.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4855) eIF3_N PF09440.10 EAX95368.1 - 4.9 7.6 10.2 1.7 9.1 0.5 3.1 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Pkinase PF00069.25 EAX95369.1 - 7.1e-30 104.3 0.0 8.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95369.1 - 2.1e-17 63.3 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX95369.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX95369.1 - 0.00018 20.4 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX95369.1 - 0.0004 20.4 0.0 0.00058 19.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EAX95369.1 - 0.055 12.7 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pheromone PF08015.11 EAX95370.1 - 0.034 15.2 0.8 0.44 11.6 0.0 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone GEP5 PF17053.5 EAX95370.1 - 0.05 13.5 0.3 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Genetic interactor of prohibitin 5 C2 PF00168.30 EAX95371.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 C2 domain Apt1 PF10351.9 EAX95372.1 - 0.0033 16.3 7.1 0.0038 16.2 7.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SOG2 PF10428.9 EAX95372.1 - 0.006 15.8 13.8 0.0066 15.7 13.8 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein DUF4614 PF15391.6 EAX95372.1 - 0.016 15.2 15.1 0.029 14.4 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 EAX95372.1 - 0.067 11.7 7.1 0.065 11.8 7.1 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EAX95372.1 - 0.19 11.2 3.4 0.22 11.0 3.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 EAX95372.1 - 0.21 11.4 14.0 0.26 11.2 14.0 1.1 1 0 0 1 1 1 0 SPX domain RAP1 PF07218.11 EAX95372.1 - 0.38 9.0 14.9 0.41 8.9 14.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec3_C PF09763.9 EAX95372.1 - 0.7 8.2 2.4 0.75 8.1 2.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Miga PF10265.9 EAX95372.1 - 0.78 8.6 4.9 1.2 8.0 4.9 1.3 1 0 0 1 1 1 0 Mitoguardin CCDC106 PF15794.5 EAX95372.1 - 1.9 8.1 7.5 2.8 7.6 7.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 EVI2A PF05399.11 EAX95372.1 - 2.8 7.5 12.6 5 6.6 12.6 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Presenilin PF01080.17 EAX95372.1 - 3.1 6.5 6.8 0.93 8.2 3.6 1.6 2 0 0 2 2 2 0 Presenilin GREB1 PF15782.5 EAX95372.1 - 7.8 3.5 10.0 8.8 3.3 10.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rhodanese PF00581.20 EAX95373.1 - 2.6e-12 47.2 0.0 3.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 EAX95374.1 - 3.3e-50 170.9 0.0 4e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95374.1 - 3e-30 105.4 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95374.1 - 1.3e-06 27.9 0.0 0.00011 21.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EAX95374.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX95374.1 - 0.074 12.0 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Alpha-amylase PF00128.24 EAX95375.1 - 1e-42 147.0 2.6 3.9e-26 92.4 0.6 2.4 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CASP_C PF08172.12 EAX95376.1 - 0.0021 17.4 15.3 0.0025 17.2 15.3 1.0 1 0 0 1 1 1 1 CASP C terminal NPV_P10 PF05531.12 EAX95376.1 - 0.0024 18.3 7.1 0.15 12.6 3.3 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein TelA PF05816.11 EAX95376.1 - 0.005 16.0 9.3 0.0061 15.7 9.3 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) HSBP1 PF06825.12 EAX95376.1 - 0.0069 16.2 6.6 0.065 13.1 0.8 3.0 3 0 0 3 3 3 1 Heat shock factor binding protein 1 DUF3584 PF12128.8 EAX95376.1 - 0.0073 13.9 18.3 0.0085 13.7 18.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 EAX95376.1 - 0.019 15.3 17.9 2.2 8.6 10.5 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF885 PF05960.11 EAX95376.1 - 0.019 14.7 2.5 0.024 14.3 2.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) EzrA PF06160.12 EAX95376.1 - 0.033 12.4 17.4 0.6 8.2 11.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1515 PF07439.11 EAX95376.1 - 0.035 14.1 6.6 0.21 11.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FlxA PF14282.6 EAX95376.1 - 0.046 13.7 28.7 0.2 11.7 20.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Syntaxin-6_N PF09177.11 EAX95376.1 - 0.048 14.2 13.6 0.58 10.7 5.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 EAX95376.1 - 0.057 12.1 17.0 0.068 11.8 17.0 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EAX95376.1 - 0.057 13.0 12.5 0.067 12.7 12.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 EAX95376.1 - 0.068 13.7 20.6 0.91 10.1 2.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 EAX95376.1 - 0.1 12.9 7.6 0.3 11.4 2.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 EAX95376.1 - 0.11 11.7 17.1 0.083 12.1 15.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein KxDL PF10241.9 EAX95376.1 - 0.11 12.7 14.0 0.49 10.7 2.6 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein Histone_HNS PF00816.21 EAX95376.1 - 0.12 13.3 11.2 0.17 12.8 4.4 2.2 2 0 0 2 2 2 0 H-NS histone family DUF5446 PF17522.2 EAX95376.1 - 0.13 12.4 14.0 4.5 7.5 1.1 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5446) PIN_8 PF18476.1 EAX95376.1 - 0.2 11.5 13.2 0.27 11.1 13.2 1.3 1 0 0 1 1 1 0 PIN like domain DUF1664 PF07889.12 EAX95376.1 - 0.24 11.4 14.8 4.5 7.3 9.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EAX95376.1 - 0.24 11.7 18.6 5.3 7.4 5.6 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 EAX95376.1 - 0.24 11.6 22.3 1.1 9.5 15.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 EAX95376.1 - 0.25 10.6 7.5 0.72 9.1 6.0 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Focal_AT PF03623.13 EAX95376.1 - 0.25 11.3 9.3 0.93 9.5 0.4 2.2 1 1 1 2 2 2 0 Focal adhesion targeting region DUF2203 PF09969.9 EAX95376.1 - 0.28 11.9 13.0 0.74 10.5 6.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Allexi_40kDa PF05549.11 EAX95376.1 - 0.33 10.4 14.5 0.61 9.6 11.5 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein CHASE3 PF05227.13 EAX95376.1 - 0.35 10.8 7.3 3 7.8 7.3 2.2 1 1 0 1 1 1 0 CHASE3 domain Uso1_p115_C PF04871.13 EAX95376.1 - 0.36 11.2 22.7 3 8.2 3.4 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2031 PF09592.10 EAX95376.1 - 0.4 10.1 17.8 1.4 8.4 17.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) Sec2p PF06428.11 EAX95376.1 - 0.44 10.6 19.8 0.17 11.9 2.3 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Occludin_ELL PF07303.13 EAX95376.1 - 0.45 11.3 13.7 2.3 9.0 0.4 2.5 1 1 2 3 3 3 0 Occludin homology domain DUF3422 PF11902.8 EAX95376.1 - 0.45 9.6 8.4 0.81 8.7 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3422) Baculo_PEP_C PF04513.12 EAX95376.1 - 0.48 10.5 6.9 0.64 10.0 4.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 EAX95376.1 - 0.49 8.3 13.6 0.71 7.7 13.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 EAX95376.1 - 0.5 10.8 16.8 1.1 9.7 0.8 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.6 EAX95376.1 - 0.52 10.7 20.1 3.4 8.1 9.6 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DHHA1 PF02272.19 EAX95376.1 - 0.52 10.7 6.8 0.25 11.8 1.8 2.1 2 0 0 2 2 2 0 DHHA1 domain Lebercilin PF15619.6 EAX95376.1 - 0.54 9.9 23.7 0.85 9.2 3.1 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 EAX95376.1 - 0.54 10.7 20.6 8.9 6.7 20.6 2.0 1 1 0 1 1 1 0 Fez1 RP-C_C PF11800.8 EAX95376.1 - 0.58 10.2 10.3 0.79 9.8 10.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Not3 PF04065.15 EAX95376.1 - 0.59 9.5 20.6 0.18 11.2 10.5 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component MDM31_MDM32 PF08118.11 EAX95376.1 - 0.6 8.7 7.7 0.69 8.5 7.7 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Syntaxin PF00804.25 EAX95376.1 - 0.62 9.7 17.8 3.4 7.3 16.9 2.0 1 1 0 1 1 1 0 Syntaxin Mitofilin PF09731.9 EAX95376.1 - 0.66 8.8 17.6 0.82 8.4 17.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FapA PF03961.13 EAX95376.1 - 0.67 8.5 21.8 0.79 8.3 14.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 EAX95376.1 - 0.72 8.7 23.7 4.7 6.0 23.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Lipoprotein_2 PF00921.17 EAX95376.1 - 0.73 9.3 13.2 1.5 8.3 13.3 1.5 1 1 0 1 1 1 0 Borrelia lipoprotein DUF5082 PF16888.5 EAX95376.1 - 0.75 10.1 21.5 5.8 7.2 21.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CENP-H PF05837.12 EAX95376.1 - 0.85 10.0 23.0 3 8.3 14.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) AATF-Che1 PF13339.6 EAX95376.1 - 0.88 10.3 16.0 2.5 8.8 16.0 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor COG2 PF06148.11 EAX95376.1 - 0.91 9.6 13.2 3.9 7.6 0.5 2.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.6 EAX95376.1 - 0.93 9.8 20.8 11 6.4 20.8 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein PRKG1_interact PF15898.5 EAX95376.1 - 0.93 10.4 20.8 0.18 12.7 11.1 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2730 PF10805.8 EAX95376.1 - 0.95 9.6 11.9 6.7 6.9 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LUC7 PF03194.15 EAX95376.1 - 0.99 9.0 14.3 1.4 8.5 14.3 1.3 1 0 0 1 1 1 0 LUC7 N_terminus DUF3381 PF11861.8 EAX95376.1 - 1 9.2 22.1 2.9 7.7 21.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) Phasin PF05597.11 EAX95376.1 - 1 9.4 13.5 0.4 10.7 4.6 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tropomyosin_1 PF12718.7 EAX95376.1 - 1.1 9.5 26.2 0.91 9.7 11.3 2.4 1 1 1 2 2 2 0 Tropomyosin like DCB PF16213.5 EAX95376.1 - 1.1 8.9 8.6 0.13 11.9 3.6 1.8 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 GAS PF13851.6 EAX95376.1 - 1.1 8.6 23.7 48 3.2 22.4 2.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HEPN_AbiV PF18728.1 EAX95376.1 - 1.1 9.4 8.5 2 8.6 8.5 1.5 1 1 0 1 1 1 0 AbiV FemAB PF02388.16 EAX95376.1 - 1.1 8.0 20.6 1 8.2 4.1 2.0 1 1 1 2 2 2 0 FemAB family FliJ PF02050.16 EAX95376.1 - 1.4 9.2 16.3 4.1 7.7 16.2 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein DUF4665 PF15679.5 EAX95376.1 - 1.6 9.4 17.2 1.4 9.6 2.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) T2SSM PF04612.12 EAX95376.1 - 1.6 8.8 10.7 2.8 8.0 1.0 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Fib_alpha PF08702.10 EAX95376.1 - 1.6 8.9 18.8 2.4 8.3 17.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EAX95376.1 - 1.7 6.5 10.9 1.9 6.4 10.9 1.1 1 0 0 1 1 1 0 Prominin Ribonuc_2-5A PF06479.12 EAX95376.1 - 1.7 8.8 7.4 2.1 8.5 7.1 1.3 1 1 0 1 1 1 0 Ribonuclease 2-5A TrwC PF08751.11 EAX95376.1 - 1.8 8.0 8.4 3 7.3 8.4 1.4 1 1 0 1 1 1 0 TrwC relaxase DUF4407 PF14362.6 EAX95376.1 - 1.8 7.8 12.6 2.6 7.3 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF745 PF05335.13 EAX95376.1 - 1.9 8.2 14.0 0.47 10.1 9.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 EAX95376.1 - 1.9 7.2 21.0 0.85 8.4 13.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.8 EAX95376.1 - 2 7.7 19.8 4.1 6.6 1.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.11 EAX95376.1 - 2.1 7.9 15.7 4.6 6.8 1.4 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Tweety PF04906.13 EAX95376.1 - 2.3 6.8 7.2 1.4 7.5 2.1 1.9 1 1 1 2 2 2 0 Tweety PEP-utilisers_N PF05524.13 EAX95376.1 - 2.6 8.3 7.6 5.4 7.2 0.3 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal THOC7 PF05615.13 EAX95376.1 - 2.8 8.2 21.0 5.3 7.3 5.4 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 HR1 PF02185.16 EAX95376.1 - 2.9 8.1 21.6 5 7.3 2.6 3.2 1 1 1 3 3 3 0 Hr1 repeat DUF883 PF05957.13 EAX95376.1 - 2.9 8.5 8.9 8.7 7.0 2.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1917 PF08939.10 EAX95376.1 - 3.4 7.5 13.1 18 5.1 13.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) YlqD PF11068.8 EAX95376.1 - 3.7 7.9 20.9 0.31 11.4 6.6 2.1 1 1 1 2 2 2 0 YlqD protein DUF2408 PF10303.9 EAX95376.1 - 3.8 8.1 15.1 8.1 7.0 15.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF812 PF05667.11 EAX95376.1 - 3.9 6.2 24.2 6.6 5.5 24.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) MIP-T3_C PF17749.1 EAX95376.1 - 4 7.4 22.6 2.7 7.9 5.0 3.0 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Swi5 PF07061.11 EAX95376.1 - 4 7.6 20.2 11 6.2 2.0 3.2 2 1 1 3 3 3 0 Swi5 Atg14 PF10186.9 EAX95376.1 - 4.1 6.4 23.0 1.1 8.3 14.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 EAX95376.1 - 4.7 7.0 22.1 0.57 10.0 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Blo-t-5 PF11642.8 EAX95376.1 - 4.7 7.2 13.3 11 6.0 6.5 2.3 1 1 1 2 2 2 0 Mite allergen Blo t 5 ISG65-75 PF11727.8 EAX95376.1 - 4.9 6.3 17.6 1.9 7.6 8.3 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF2390 PF09523.10 EAX95376.1 - 5.1 7.5 8.5 6.8 7.1 1.0 2.5 1 1 2 3 3 2 0 Protein of unknown function (DUF2390) DUF16 PF01519.16 EAX95376.1 - 5.6 7.5 20.7 0.92 10.0 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliD_N PF02465.18 EAX95376.1 - 6.8 7.5 12.1 18 6.1 1.1 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ran-binding PF05508.11 EAX95376.1 - 6.9 5.6 14.1 1.7 7.5 7.3 2.0 1 1 1 2 2 2 0 RanGTP-binding protein Csm1_N PF18504.1 EAX95376.1 - 6.9 7.1 25.4 13 6.2 3.1 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain G10 PF01125.17 EAX95376.1 - 7.8 6.2 11.8 1.6e+02 2.0 1.2 2.4 1 1 1 2 2 2 0 G10 protein DUF4391 PF14335.6 EAX95376.1 - 8 6.1 19.5 1.8 8.2 3.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4391) DUF2802 PF10975.8 EAX95376.1 - 9.1 6.5 11.9 39 4.5 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Ax_dynein_light PF10211.9 EAX95376.1 - 9.5 6.1 23.5 17 5.3 3.4 2.7 1 1 2 3 3 3 0 Axonemal dynein light chain MtrG PF04210.13 EAX95376.1 - 9.5 6.2 6.9 1.4 8.8 1.0 2.4 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G XhlA PF10779.9 EAX95376.1 - 9.6 6.5 22.9 1.6 9.0 9.8 3.5 2 2 2 4 4 4 0 Haemolysin XhlA Shikimate_DH PF01488.20 EAX95378.1 - 0.005 16.9 0.4 0.088 12.9 0.1 2.2 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DUF4894 PF16235.5 EAX95379.1 - 0.053 13.9 1.4 0.1 13.0 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) GPS2_interact PF15784.5 EAX95380.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX95381.1 - 0.089 12.8 10.0 0.14 12.1 10.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX95382.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX95383.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX95383.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX95384.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain T5orf172 PF10544.9 EAX95385.1 - 6.8e-07 29.8 0.7 1.9e-06 28.3 0.2 2.0 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX95385.1 - 0.013 15.1 0.5 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain ASH PF15780.5 EAX95386.1 - 5.5e-39 132.3 56.8 9.8e-06 25.7 0.7 20.3 20 1 0 20 20 20 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EAX95386.1 - 7.5e-12 45.1 41.7 0.023 14.7 0.2 15.7 17 0 0 17 17 17 4 Protein of unknown function (DUF1573) PapD-like PF14874.6 EAX95386.1 - 8e-11 42.0 5.1 2 8.6 0.0 9.6 10 0 0 10 10 10 3 Flagellar-associated PapD-like DUF5001 PF16392.5 EAX95386.1 - 0.0018 18.2 23.6 4.2 7.4 0.1 9.8 8 0 0 8 8 8 2 Ig-like domain AAA_18 PF13238.6 EAX95386.1 - 0.0059 17.2 0.0 0.037 14.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF2489 PF10675.9 EAX95386.1 - 1.2 9.1 9.6 0.28 11.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Big_2 PF02368.18 EAX95386.1 - 3.5 7.6 5.4 6.9 6.6 0.0 4.5 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 2) TMEM131_like PF12371.8 EAX95386.1 - 5.4 7.3 31.9 6.3 7.1 0.0 10.0 12 0 0 12 12 12 0 Transmembrane protein 131-like EF-G-binding_N PF07299.11 EAX95387.1 - 0.041 14.4 0.2 0.97 10.0 0.1 3.5 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal ANAPC3 PF12895.7 EAX95387.1 - 0.11 12.8 1.6 7.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EAX95387.1 - 0.13 12.4 0.8 1.5 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat YmzC PF14157.6 EAX95387.1 - 0.13 12.3 1.3 1.7 8.8 0.1 3.0 3 0 0 3 3 3 0 YmzC-like protein Fer4_24 PF18109.1 EAX95388.1 - 0.0027 17.9 0.5 0.1 12.9 0.2 2.5 2 0 0 2 2 2 1 Ferredoxin I 4Fe-4S cluster domain UvrB PF12344.8 EAX95388.1 - 0.0072 16.1 0.4 0.09 12.6 0.0 2.6 2 0 0 2 2 2 1 Ultra-violet resistance protein B DUF848 PF05852.11 EAX95388.1 - 0.0081 16.3 3.9 0.0081 16.3 3.9 2.1 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) SNARE PF05739.19 EAX95388.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.4 3 0 0 3 3 3 0 SNARE domain Med9 PF07544.13 EAX95388.1 - 0.018 15.1 8.6 0.13 12.4 1.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AHD PF17793.1 EAX95388.1 - 0.021 14.6 0.4 0.078 12.8 0.1 2.2 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Lectin_N PF03954.14 EAX95388.1 - 0.022 14.5 6.4 0.12 12.1 0.8 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CLZ PF16526.5 EAX95388.1 - 0.05 14.0 0.5 0.05 14.0 0.5 3.2 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 EAX95388.1 - 0.1 12.9 8.7 5.6 7.3 0.3 3.1 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 EAX95388.1 - 0.1 12.8 13.8 0.038 14.2 2.7 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PilJ PF13675.6 EAX95388.1 - 0.14 12.2 1.1 3.3 7.8 0.0 2.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1640 PF07798.11 EAX95388.1 - 0.26 11.3 14.0 0.5 10.4 4.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) MCPsignal PF00015.21 EAX95388.1 - 0.32 10.8 4.7 0.17 11.7 1.9 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CREPT PF16566.5 EAX95388.1 - 1.2 9.4 12.0 0.16 12.1 2.4 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2203 PF09969.9 EAX95388.1 - 1.2 9.9 9.6 1.4 9.7 1.1 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Dad1 PF08649.10 EAX95388.1 - 1.3 9.3 4.8 7.1 6.9 0.7 3.4 3 1 1 4 4 4 0 DASH complex subunit Dad1 DASH_Dam1 PF08653.10 EAX95388.1 - 1.5 8.7 4.1 41 4.1 0.2 3.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 EAX95388.1 - 1.6 8.9 15.8 0.89 9.7 4.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 EAX95388.1 - 1.8 8.3 6.8 0.96 9.1 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ING PF12998.7 EAX95388.1 - 3.2 8.4 13.5 0.44 11.2 2.6 3.0 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Prominin PF05478.11 EAX95388.1 - 6.6 4.6 10.2 4.2 5.2 5.9 1.9 1 1 1 2 2 2 0 Prominin Vac14_Fab1_bd PF12755.7 EAX95389.1 - 0.47 11.1 2.6 55 4.4 0.0 4.1 2 2 3 5 5 5 0 Vacuolar 14 Fab1-binding region TFIIF_alpha PF05793.12 EAX95389.1 - 2.2 6.8 32.4 5 5.6 32.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cnd1 PF12717.7 EAX95389.1 - 3.6 7.6 16.4 0.035 14.2 1.0 4.0 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ras PF00071.22 EAX95391.1 - 2.8e-43 147.3 0.2 3.2e-43 147.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95391.1 - 1e-31 109.6 0.1 1.4e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95391.1 - 2.5e-14 53.1 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX95391.1 - 4.5e-06 26.7 0.1 0.0022 18.0 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX95391.1 - 5.7e-06 26.4 0.1 9e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX95391.1 - 6.3e-06 25.7 0.0 8.6e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAX95391.1 - 0.00071 19.1 0.0 0.017 14.7 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EAX95391.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Adeno_E3_15_3 PF03307.14 EAX95391.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region PAP2 PF01569.21 EAX95393.1 - 7.1e-20 71.2 1.3 8e-20 71.0 1.3 1.0 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.21 EAX95393.1 - 0.001 18.9 0.4 0.0011 18.7 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family PAP2_3 PF14378.6 EAX95393.1 - 0.0095 15.6 5.0 0.02 14.6 5.0 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF2955 PF11168.8 EAX95393.1 - 0.032 14.1 4.5 0.042 13.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) NDUF_B4 PF07225.12 EAX95393.1 - 0.13 12.1 0.3 0.23 11.4 0.2 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Sel1 PF08238.12 EAX95395.1 - 0.0011 19.5 1.6 0.21 12.3 0.1 3.6 3 0 0 3 3 3 1 Sel1 repeat YoaP PF14268.6 EAX95395.1 - 0.036 13.6 1.6 0.27 10.8 0.0 2.9 3 0 0 3 3 3 0 YoaP-like DUF960 PF06124.11 EAX95396.1 - 0.093 13.4 1.5 0.44 11.2 0.3 2.7 2 1 1 3 3 3 0 Staphylococcal protein of unknown function (DUF960) TMEM154 PF15102.6 EAX95397.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family CAP PF00188.26 EAX95397.1 - 0.014 16.2 0.6 0.031 15.1 0.6 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF1180 PF06679.12 EAX95397.1 - 0.4 11.1 3.0 0.61 10.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pox_A32 PF04665.12 EAX95398.1 - 6.1e-07 29.1 2.6 6.1e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX95398.1 - 4.4e-05 23.3 0.3 0.41 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX95398.1 - 8.1e-05 22.9 0.2 0.00053 20.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX95398.1 - 0.00011 22.3 3.1 0.00024 21.2 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX95398.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX95398.1 - 0.0021 17.9 0.5 0.0042 16.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX95398.1 - 0.0024 17.6 0.5 0.013 15.1 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX95398.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX95398.1 - 0.06 12.8 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX95398.1 - 0.073 12.6 0.1 0.23 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX95398.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX95398.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX95398.1 - 0.13 12.7 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX95398.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX95399.1 - 2.9e-153 508.2 12.1 3.6e-153 507.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX95399.1 - 0.059 13.2 0.7 0.21 11.5 0.2 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAX95399.1 - 1.1 9.8 4.0 2.1 8.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX95399.1 - 3.1 8.3 6.9 1.8 9.1 0.4 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX95400.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX95401.1 - 2.9e-47 160.9 0.7 4e-47 160.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) TPR_MLP1_2 PF07926.12 EAX95402.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX95402.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX95402.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family TFIIA PF03153.13 EAX95403.1 - 0.31 11.0 11.6 0.32 10.9 11.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spectrin PF00435.21 EAX95404.1 - 0.33 11.5 8.5 1.6 9.2 3.5 3.1 3 0 0 3 3 3 0 Spectrin repeat Wbp11 PF09429.10 EAX95404.1 - 0.77 10.2 7.5 0.68 10.4 4.0 2.6 2 0 0 2 2 2 0 WW domain binding protein 11 DUF3447 PF11929.8 EAX95405.1 - 7.8e-40 134.7 6.3 7.8e-40 134.7 6.3 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX95405.1 - 5.9e-37 126.1 24.4 2.2e-17 63.4 2.4 3.9 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95405.1 - 5.6e-30 103.3 13.4 3.3e-12 46.7 0.4 6.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX95405.1 - 2.9e-25 87.6 10.7 7e-08 32.6 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX95405.1 - 2e-24 85.3 10.4 8e-10 38.8 0.2 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95405.1 - 4.9e-24 81.8 17.1 5.6e-06 26.3 0.1 7.6 7 1 1 8 8 8 4 Ankyrin repeat CdhD PF03599.16 EAX95405.1 - 0.054 12.2 0.0 0.26 10.0 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit DUF3986 PF13143.6 EAX95405.1 - 0.056 14.4 1.6 0.056 14.4 1.6 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3986) AAA_12 PF13087.6 EAX95406.1 - 1.5e-51 174.9 1.9 6e-51 172.9 0.4 2.5 2 0 0 2 2 2 1 AAA domain Dna2 PF08696.11 EAX95406.1 - 8.3e-51 172.7 0.1 2.5e-50 171.1 0.0 1.8 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_11 PF13086.6 EAX95406.1 - 1.3e-32 113.7 0.1 1e-17 64.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EAX95406.1 - 1.7e-18 67.1 0.0 3.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX95406.1 - 2.6e-11 44.0 0.0 5.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EAX95406.1 - 3.2e-08 33.8 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EAX95406.1 - 2.4e-07 30.8 0.1 0.003 17.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EAX95406.1 - 3.4e-06 27.0 0.0 1.7e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Helicase Cas_Cas4 PF01930.17 EAX95406.1 - 4.2e-06 26.9 0.0 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function DUF83 SRP54 PF00448.22 EAX95406.1 - 8.7e-05 22.2 0.1 0.00021 21.0 0.0 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EAX95406.1 - 0.00096 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 EAX95406.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EAX95406.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EAX95406.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAX95406.1 - 0.0088 16.3 0.2 0.064 13.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EAX95406.1 - 0.015 15.8 0.0 0.06 13.8 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EAX95406.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 EAX95406.1 - 0.025 13.5 0.1 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EAX95406.1 - 0.029 14.9 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EAX95406.1 - 0.031 14.8 0.0 0.086 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX95406.1 - 0.034 14.1 0.1 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EAX95406.1 - 0.037 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain TPP_enzyme_M PF00205.22 EAX95406.1 - 0.043 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain SIS PF01380.22 EAX95406.1 - 0.055 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 SIS domain UvrD_C_2 PF13538.6 EAX95406.1 - 0.073 12.9 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 EAX95406.1 - 0.13 12.2 2.1 0.37 10.8 0.1 2.8 4 1 0 4 4 2 0 Type III restriction enzyme, res subunit DUF3060 PF11259.8 EAX95407.1 - 0.0013 18.3 3.9 0.0068 16.1 1.6 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3060) TMEM154 PF15102.6 EAX95407.1 - 0.047 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Laminin_II PF06009.12 EAX95408.1 - 0.00012 22.2 9.3 0.00012 22.2 9.3 9.9 2 2 7 9 9 8 2 Laminin Domain II KASH_CCD PF14662.6 EAX95408.1 - 0.00033 20.5 38.1 0.00033 20.5 38.1 7.5 2 2 3 6 6 4 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EAX95408.1 - 0.0013 18.1 22.7 0.0013 18.1 22.7 8.3 3 2 4 8 8 7 2 Growth-arrest specific micro-tubule binding RasGAP_C PF03836.15 EAX95408.1 - 0.0037 17.4 3.4 0.0037 17.4 3.4 9.2 3 2 4 7 7 3 1 RasGAP C-terminus DUF3450 PF11932.8 EAX95408.1 - 0.0063 15.9 13.0 0.0063 15.9 13.0 9.5 3 2 7 10 10 10 5 Protein of unknown function (DUF3450) DUF4201 PF13870.6 EAX95408.1 - 0.0089 15.8 22.8 0.0089 15.8 22.8 7.9 4 2 4 8 8 7 4 Domain of unknown function (DUF4201) DUF4200 PF13863.6 EAX95408.1 - 0.0097 16.3 14.8 0.0097 16.3 14.8 8.9 3 2 6 9 9 9 3 Domain of unknown function (DUF4200) YabA PF06156.13 EAX95408.1 - 0.019 15.6 15.0 0.019 15.6 15.0 10.9 4 2 7 11 11 10 0 Initiation control protein YabA DUF4713 PF15831.5 EAX95408.1 - 1 9.8 3.9 0.48 10.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) TMF_TATA_bd PF12325.8 EAX95408.1 - 1.6 9.0 138.8 0.082 13.1 21.4 10.0 3 2 6 10 10 10 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EAX95408.1 - 5.1 7.1 158.5 0.072 13.1 5.5 8.3 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EAX95408.1 - 9.9 4.7 139.0 0.023 13.4 24.9 5.0 2 2 3 5 5 5 0 AAA domain AAA_12 PF13087.6 EAX95410.1 - 5.5e-39 133.9 0.0 6.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAX95410.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Ecm29 PF13001.7 EAX95411.1 - 4.8e-09 35.4 0.5 4.8e-09 35.4 0.5 2.5 2 1 1 3 3 3 1 Proteasome stabiliser Pkinase_Tyr PF07714.17 EAX95412.1 - 3.1e-68 229.9 0.0 9.8e-68 228.2 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95412.1 - 2e-56 191.3 0.0 5.6e-56 189.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain IFRD PF05004.13 EAX95412.1 - 2.9e-05 23.4 2.5 6.9e-05 22.1 2.5 1.7 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) RICTOR_M PF14666.6 EAX95412.1 - 0.001 18.8 0.3 0.03 14.1 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain V-ATPase_H_C PF11698.8 EAX95412.1 - 0.0034 17.5 13.3 1.5 9.0 0.1 6.0 5 1 1 6 6 6 2 V-ATPase subunit H Pkinase_fungal PF17667.1 EAX95412.1 - 0.052 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Guanylate_cyc PF00211.20 EAX95412.1 - 0.15 11.7 0.7 0.54 9.9 0.1 2.1 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain FlxA PF14282.6 EAX95412.1 - 0.2 11.7 0.8 20 5.2 0.2 2.6 2 0 0 2 2 2 0 FlxA-like protein DCB PF16213.5 EAX95412.1 - 0.34 10.6 6.9 0.43 10.2 1.8 3.5 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 PAN_3 PF08277.12 EAX95412.1 - 9.1 6.2 7.2 37 4.2 0.2 3.1 2 0 0 2 2 2 0 PAN-like domain Myb_DNA-binding PF00249.31 EAX95413.1 - 5.5e-26 90.5 3.1 2.2e-12 47.0 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95413.1 - 4.2e-19 68.5 2.8 1e-11 44.9 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX95413.1 - 0.0027 17.6 0.1 0.062 13.2 0.1 2.5 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 EAX95413.1 - 1.9 8.6 8.3 2.5 8.2 0.7 3.8 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain ubiquitin PF00240.23 EAX95414.1 - 4.8e-28 96.7 1.0 2.6e-18 65.5 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX95414.1 - 1.4e-11 44.0 4.7 8.6e-08 31.9 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX95414.1 - 0.00063 20.1 0.2 0.0038 17.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain GABP-alpha PF11620.8 EAX95414.1 - 0.0012 19.0 0.3 0.0026 17.9 0.3 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain Rad60-SLD_2 PF13881.6 EAX95414.1 - 0.0083 16.2 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EAX95414.1 - 0.17 11.9 0.9 2.5 8.2 0.1 2.7 2 1 1 3 3 3 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EAX95414.1 - 0.25 11.8 1.5 2.5 8.6 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin-like domain POTRA_1 PF08478.10 EAX95415.1 - 0.077 13.3 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 POTRA domain, FtsQ-type Gly-zipper_Omp PF13488.6 EAX95416.1 - 0.0045 17.0 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX95416.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX95416.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAX95418.1 - 4.8e-05 22.9 2.6 7.8e-05 22.3 2.6 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX95418.1 - 0.0059 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX95418.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAX95420.1 - 8.8e-153 506.7 13.5 1.1e-152 506.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) P4Ha_N PF08336.11 EAX95420.1 - 0.029 14.4 1.1 4.8 7.2 0.0 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NTP_transf_6 PF06042.11 EAX95420.1 - 0.1 12.4 1.0 0.2 11.5 0.5 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAX95420.1 - 0.27 11.7 5.3 0.88 10.1 0.2 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX95420.1 - 0.57 10.5 4.8 13 6.2 0.0 3.6 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAX95420.1 - 0.93 10.1 3.8 0.61 10.6 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Selenoprotein_S PF06936.11 EAX95422.1 - 6.1 6.6 13.9 26 4.5 13.9 2.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) SNF2_N PF00176.23 EAX95424.1 - 1.7e-55 188.2 3.0 3.7e-55 187.0 3.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX95424.1 - 1.3e-21 77.0 0.0 3.8e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EAX95424.1 - 1.6e-13 50.3 7.2 7.2e-10 38.6 0.3 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 EAX95424.1 - 8.7e-08 31.7 4.2 8.7e-08 31.7 4.2 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EAX95424.1 - 5.6e-07 29.7 2.5 9.6e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX95424.1 - 5.4e-06 26.3 0.0 2.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase FYRN PF05964.14 EAX95424.1 - 0.00018 21.2 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EAX95424.1 - 0.00051 20.1 0.1 0.003 17.7 0.0 2.4 2 0 0 2 2 2 1 F/Y rich C-terminus Somatostatin PF03002.15 EAX95425.1 - 3.7 7.6 5.5 25 4.9 0.4 2.5 2 0 0 2 2 2 0 Somatostatin/Cortistatin family LRR_5 PF13306.6 EAX95426.1 - 3e-261 851.6 206.2 2.9e-30 104.9 4.5 11.2 2 2 10 12 12 12 12 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95426.1 - 4.9e-20 71.0 19.5 0.11 12.3 0.2 15.9 13 5 5 18 18 18 10 Leucine rich repeat LRR_4 PF12799.7 EAX95426.1 - 0.0055 17.1 23.5 39 4.9 0.0 11.4 11 1 2 13 13 13 1 Leucine Rich repeats (2 copies) FlgT_M PF16539.5 EAX95427.1 - 0.16 12.1 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain LRR_1 PF00560.33 EAX95428.1 - 7.3 7.6 0.0 7.3 7.6 0.0 3.9 4 2 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 EAX95429.1 - 6.6e-61 206.0 0.2 1e-60 205.3 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95429.1 - 1.9e-41 142.0 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95429.1 - 2e-07 30.7 0.0 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EAX95429.1 - 0.00032 20.7 0.1 0.0085 16.0 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX95429.1 - 0.001 18.7 2.8 0.007 16.0 0.6 2.4 1 1 1 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EAX95429.1 - 0.022 13.7 1.1 0.059 12.3 1.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EAX95429.1 - 0.031 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EAX95430.1 - 2.4e-25 88.4 1.8 9.6e-15 54.5 0.5 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95430.1 - 1.5e-24 86.0 6.3 1.6e-14 53.9 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95430.1 - 0.00021 21.3 0.6 0.07 13.2 0.3 2.8 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX95430.1 - 0.00072 19.9 3.8 0.18 12.2 1.1 2.6 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX95430.1 - 0.0044 17.2 0.3 0.05 13.8 0.1 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX95430.1 - 0.0065 16.3 0.6 0.021 14.7 0.5 1.9 2 1 0 2 2 2 1 Myb DNA-binding like XH PF03469.14 EAX95430.1 - 0.0081 16.1 0.5 2.2 8.2 0.0 2.4 1 1 1 2 2 2 2 XH domain DUF1825 PF08855.10 EAX95430.1 - 0.014 15.3 0.3 0.037 13.9 0.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) FCH PF00611.23 EAX95430.1 - 0.024 14.9 0.2 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Nore1-SARAH PF16517.5 EAX95430.1 - 0.027 14.4 0.8 2 8.4 0.2 2.9 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Peptidase_C39_2 PF13529.6 EAX95430.1 - 0.084 13.4 0.1 0.11 13.0 0.1 1.4 1 1 0 1 1 1 0 Peptidase_C39 like family Myb_DNA-binding PF00249.31 EAX95431.1 - 1.6e-25 89.0 3.3 3.9e-14 52.6 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95431.1 - 6.7e-24 83.9 6.6 1.8e-14 53.7 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95431.1 - 3.6e-06 27.0 1.9 0.012 15.6 0.1 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX95431.1 - 2.4e-05 24.6 1.5 0.0048 17.2 0.1 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX95431.1 - 0.0027 17.6 0.5 0.05 13.5 0.0 2.4 2 1 0 2 2 2 1 Myb DNA-binding like XH PF03469.14 EAX95431.1 - 0.024 14.5 1.0 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 XH domain FCH PF00611.23 EAX95431.1 - 0.055 13.7 0.8 1.5 9.2 0.2 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain PseudoU_synth_1 PF01416.20 EAX95431.1 - 0.092 13.2 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 tRNA pseudouridine synthase Rap1_C PF11626.8 EAX95431.1 - 0.19 11.8 1.6 4.7 7.4 0.4 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Metallophos PF00149.28 EAX95432.1 - 6.7e-32 111.7 0.2 9e-32 111.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KilA-N PF04383.13 EAX95434.1 - 1.5e-42 144.0 0.1 2.2e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain DUF4106 PF13388.6 EAX95435.1 - 1.7e-272 903.8 16.9 1.7e-272 903.8 16.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX95435.1 - 0.1 12.9 1.9 1.8 8.9 0.1 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated PAS PF00989.25 EAX95435.1 - 0.22 11.6 1.0 14 5.7 0.2 3.1 3 0 0 3 3 3 0 PAS fold Metallophos PF00149.28 EAX95436.1 - 8.8e-33 114.5 0.0 1.2e-32 114.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX95436.1 - 0.028 14.6 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 EAX95437.1 - 1.8e-13 50.9 0.3 2.1e-13 50.7 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95437.1 - 1.6e-11 44.2 0.5 9.4e-08 32.2 0.1 2.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX95437.1 - 8.5e-11 41.8 0.4 5.3e-07 29.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX95437.1 - 4e-10 40.0 0.4 1.6e-07 31.7 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95437.1 - 6.1e-08 32.3 0.0 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Shigella_OspC PF06128.11 EAX95437.1 - 0.0011 18.7 0.2 0.0028 17.4 0.1 1.6 1 1 1 2 2 2 1 Shigella flexneri OspC protein ASF1_hist_chap PF04729.13 EAX95437.1 - 0.084 12.8 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 ASF1 like histone chaperone DUF3447 PF11929.8 EAX95438.1 - 4.4e-37 125.9 5.7 4.4e-37 125.9 5.7 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX95438.1 - 0.0085 16.7 0.1 0.027 15.1 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) PriA_3primeBD PF17764.1 EAX95438.1 - 0.084 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) RRM_1 PF00076.22 EAX95439.1 - 8e-11 41.6 0.8 0.00023 20.9 0.3 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF6_C PF07571.13 EAX95440.1 - 2.2e-15 56.8 0.0 4.1e-14 52.7 0.0 2.6 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EAX95440.1 - 5.7e-08 32.8 0.1 1.1e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EAX95440.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Gram_pos_anchor PF00746.21 EAX95440.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Gly_rich PF12810.7 EAX95441.1 - 2.3e-40 139.1 24.3 2.6e-40 138.8 24.3 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF1640 PF07798.11 EAX95442.1 - 6.5e-05 23.0 3.1 9e-05 22.6 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF883 PF05957.13 EAX95442.1 - 9.2e-05 23.0 0.3 0.00022 21.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 EAX95442.1 - 0.00094 19.2 3.8 0.0014 18.7 3.1 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 EAX95442.1 - 0.002 18.7 1.1 0.002 18.7 1.1 1.9 2 1 0 2 2 1 1 Initiation control protein YabA Prominin PF05478.11 EAX95442.1 - 0.0045 15.0 2.2 0.0054 14.8 2.2 1.2 1 0 0 1 1 1 1 Prominin Apolipoprotein PF01442.18 EAX95442.1 - 0.0047 16.8 2.7 0.0047 16.8 2.7 1.6 2 0 0 2 2 1 1 Apolipoprotein A1/A4/E domain DUF334 PF03904.13 EAX95442.1 - 0.0048 16.5 4.4 0.0074 15.9 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) ERp29 PF07749.12 EAX95442.1 - 0.0084 17.0 3.8 0.19 12.6 0.4 2.9 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain GET2 PF08690.10 EAX95442.1 - 0.009 15.7 1.0 0.009 15.7 1.0 1.4 2 0 0 2 2 1 1 GET complex subunit GET2 SF-assemblin PF06705.11 EAX95442.1 - 0.0098 15.3 7.8 0.0098 15.3 7.8 1.5 2 0 0 2 2 2 1 SF-assemblin/beta giardin T7SS_ESX_EspC PF10824.8 EAX95442.1 - 0.013 16.0 0.9 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Fzo_mitofusin PF04799.13 EAX95442.1 - 0.015 14.9 6.4 0.24 11.0 0.2 2.3 1 1 1 2 2 2 0 fzo-like conserved region ABC_tran_CTD PF16326.5 EAX95442.1 - 0.027 14.7 9.3 0.16 12.3 1.4 3.6 2 2 2 4 4 4 0 ABC transporter C-terminal domain LMBR1 PF04791.16 EAX95442.1 - 0.031 13.2 0.7 0.037 12.9 0.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF445 PF04286.12 EAX95442.1 - 0.048 13.5 6.1 0.066 13.0 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TolA_bind_tri PF16331.5 EAX95442.1 - 0.054 13.6 1.5 0.12 12.4 0.7 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation PsiA PF06952.11 EAX95442.1 - 0.055 12.7 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 PsiA protein DASH_Dad3 PF08656.10 EAX95442.1 - 0.06 13.4 0.9 0.35 11.0 0.2 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Atg14 PF10186.9 EAX95442.1 - 0.062 12.4 3.2 0.072 12.2 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lipoprotein_2 PF00921.17 EAX95442.1 - 0.062 12.9 6.5 0.1 12.1 6.5 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Gp-FAR-1 PF05823.12 EAX95442.1 - 0.065 13.6 5.8 0.27 11.6 4.1 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2313 PF10076.9 EAX95442.1 - 0.071 13.0 1.3 0.23 11.3 1.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) AI-2E_transport PF01594.16 EAX95442.1 - 0.087 12.0 2.6 0.097 11.8 1.3 1.7 2 1 0 2 2 1 0 AI-2E family transporter HalX PF08663.10 EAX95442.1 - 0.091 13.1 1.2 0.17 12.2 0.3 2.0 2 0 0 2 2 1 0 HalX domain WXG100 PF06013.12 EAX95442.1 - 0.17 12.2 3.0 12 6.2 1.1 3.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF3086 PF11285.8 EAX95442.1 - 0.2 10.7 3.5 0.34 10.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Fib_alpha PF08702.10 EAX95442.1 - 0.21 11.8 13.9 0.17 12.0 12.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FliT PF05400.13 EAX95442.1 - 0.24 12.3 2.1 2.2 9.1 1.2 2.4 1 1 0 1 1 1 0 Flagellar protein FliT DUF1068 PF06364.12 EAX95442.1 - 0.25 11.2 4.5 0.26 11.1 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) GrpE PF01025.19 EAX95442.1 - 0.25 11.0 11.8 0.78 9.4 11.8 1.9 1 1 0 1 1 1 0 GrpE V-ATPase_G PF03179.15 EAX95442.1 - 0.31 11.6 10.7 0.083 13.4 2.3 2.5 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit TLE_N PF03920.15 EAX95442.1 - 0.34 11.0 10.1 15 5.7 8.5 2.8 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain FapA PF03961.13 EAX95442.1 - 0.39 9.3 12.1 0.22 10.1 8.3 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2935 PF11155.8 EAX95442.1 - 0.44 10.9 3.2 5.6 7.3 3.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Sec5 PF15469.6 EAX95442.1 - 0.44 10.3 10.7 2.1 8.1 9.1 2.5 1 1 1 2 2 2 0 Exocyst complex component Sec5 Alb1 PF09135.11 EAX95442.1 - 0.47 11.4 5.9 0.89 10.5 5.9 1.5 1 0 0 1 1 1 0 Alb1 Uteroglobin PF01099.17 EAX95442.1 - 0.57 10.6 3.3 3 8.2 0.6 2.6 1 1 1 2 2 2 0 Uteroglobin family FlaC_arch PF05377.11 EAX95442.1 - 0.6 10.5 9.2 0.32 11.4 0.6 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 EAX95442.1 - 0.92 8.8 6.3 1.7 7.9 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) dCache_2 PF08269.11 EAX95442.1 - 1 8.5 10.0 0.16 11.1 5.7 1.8 2 0 0 2 2 2 0 Cache domain OmpH PF03938.14 EAX95442.1 - 1.1 9.6 14.8 0.24 11.7 9.8 2.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) LUC7 PF03194.15 EAX95442.1 - 1.3 8.7 9.7 0.19 11.4 5.7 1.5 2 0 0 2 2 2 0 LUC7 N_terminus V-SNARE PF05008.15 EAX95442.1 - 1.5 9.2 7.5 0.49 10.8 2.2 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Syntaxin_2 PF14523.6 EAX95442.1 - 1.6 9.2 11.1 2.5 8.5 9.7 1.9 2 0 0 2 2 2 0 Syntaxin-like protein DUF4795 PF16043.5 EAX95442.1 - 2.1 7.9 12.7 5.1 6.6 12.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 EAX95442.1 - 2.3 8.3 10.8 1.7 8.7 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EAX95442.1 - 2.7 8.3 9.5 1.1e+02 3.2 9.5 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 EAX95442.1 - 3 8.4 8.5 52 4.5 8.5 2.5 1 1 0 1 1 1 0 YtxH-like protein Sec20 PF03908.13 EAX95442.1 - 3.3 7.7 9.6 3.4 7.6 3.3 2.6 2 1 1 3 3 2 0 Sec20 BST2 PF16716.5 EAX95442.1 - 3.6 8.2 8.9 1 10.0 0.8 2.9 1 1 0 3 3 2 0 Bone marrow stromal antigen 2 DUF1690 PF07956.11 EAX95442.1 - 3.8 7.9 10.5 0.45 10.9 1.9 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Phasin PF05597.11 EAX95442.1 - 4 7.4 9.0 8.2 6.4 0.4 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoO PF09769.9 EAX95442.1 - 4.7 7.2 5.9 33 4.5 1.5 2.7 2 1 1 3 3 2 0 Apolipoprotein O Ribosomal_S20p PF01649.18 EAX95442.1 - 5.3 7.8 9.4 11 6.7 3.3 3.1 2 1 1 3 3 3 0 Ribosomal protein S20 Allexi_40kDa PF05549.11 EAX95442.1 - 6.7 6.1 7.7 7.8 5.9 6.8 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein RNase_J_C PF17770.1 EAX95442.1 - 8.6 7.5 6.8 14 6.9 2.8 2.5 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain APG6_N PF17675.1 EAX95442.1 - 8.6 6.9 10.6 17 5.9 8.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 EAX95443.1 - 6e-23 81.5 0.1 7.4e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95443.1 - 1.1e-07 31.4 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX95443.1 - 0.00025 19.9 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX95443.1 - 0.0012 18.3 0.1 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX95443.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1325 PF07039.11 EAX95444.1 - 9.9e-26 90.4 0.2 1.5e-25 89.8 0.2 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EAX95444.1 - 4.2e-06 26.5 0.1 1.3e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EAX95444.1 - 2.9e-05 24.1 0.0 0.00013 22.0 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4537) APG17 PF04108.12 EAX95444.1 - 0.0094 15.1 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 SLATT_5 PF18160.1 EAX95444.1 - 0.019 14.3 0.2 0.027 13.8 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 P22_AR_C PF10548.9 EAX95444.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 P22AR C-terminal domain Inhibitor_I69 PF13734.6 EAX95444.1 - 0.13 12.6 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Spi protease inhibitor Glyco_transf_8 PF01501.20 EAX95445.1 - 0.0016 18.1 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 8 AP3D1 PF06375.11 EAX95445.1 - 9.7 6.4 18.4 0.05 13.9 5.8 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 zf-MYND PF01753.18 EAX95446.1 - 0.06 13.5 10.9 0.13 12.3 10.9 1.5 1 0 0 1 1 1 0 MYND finger Zn_Tnp_IS91 PF14319.6 EAX95446.1 - 2.4 8.3 9.8 3.4 7.8 8.0 2.0 2 0 0 2 2 2 0 Transposase zinc-binding domain AAA_5 PF07728.14 EAX95447.1 - 7.1e-122 401.8 0.0 1.2e-26 93.3 0.0 8.6 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAX95447.1 - 6.3e-34 116.7 0.0 2.7e-08 33.7 0.0 6.7 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EAX95447.1 - 2.5e-32 112.1 1.5 2.1e-05 24.9 0.0 8.1 8 0 0 8 8 7 5 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EAX95447.1 - 1.7e-27 95.7 12.8 1.6e-11 44.4 0.1 5.4 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_16 PF13191.6 EAX95447.1 - 2.6e-26 93.0 1.2 0.0017 18.8 0.0 7.5 6 1 0 6 6 6 5 AAA ATPase domain AAA_7 PF12775.7 EAX95447.1 - 1.3e-25 90.0 0.6 0.00033 20.2 0.0 7.0 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_6 PF12774.7 EAX95447.1 - 6.2e-24 84.6 1.0 7.5e-05 21.8 0.0 8.9 9 1 0 9 9 9 5 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 EAX95447.1 - 3.1e-19 69.2 0.0 0.0015 18.7 0.0 6.5 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EAX95447.1 - 6.3e-19 68.3 0.0 0.029 14.1 0.0 7.2 7 0 0 7 7 7 4 Sigma-54 interaction domain AAA_22 PF13401.6 EAX95447.1 - 4.4e-17 62.6 2.3 0.0094 16.2 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_18 PF13238.6 EAX95447.1 - 8.7e-17 61.9 0.7 0.02 15.5 0.0 6.6 5 0 0 5 5 5 3 AAA domain AAA_30 PF13604.6 EAX95447.1 - 1.1e-16 61.1 1.1 4.6e-05 23.2 0.0 5.5 5 0 0 5 5 5 3 AAA domain AAA_14 PF13173.6 EAX95447.1 - 5.8e-16 58.7 0.0 0.07 13.2 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA_lid_5 PF17865.1 EAX95447.1 - 1.2e-15 57.5 0.9 3.9e-13 49.4 0.1 3.7 3 0 0 3 3 2 1 Midasin AAA lid domain TsaE PF02367.17 EAX95447.1 - 1.8e-15 57.1 1.6 0.0051 16.8 0.0 5.8 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EAX95447.1 - 7.4e-14 52.1 0.4 0.067 13.3 0.0 6.7 6 0 0 6 6 6 2 AAA domain RsgA_GTPase PF03193.16 EAX95447.1 - 6.1e-12 45.8 4.0 0.11 12.4 0.0 6.4 6 0 0 6 6 5 3 RsgA GTPase Sigma54_activ_2 PF14532.6 EAX95447.1 - 1.2e-11 44.8 0.2 0.37 10.9 0.0 5.8 5 0 0 5 5 5 2 Sigma-54 interaction domain T2SSE PF00437.20 EAX95447.1 - 2.6e-11 43.1 0.2 0.43 9.6 0.1 5.5 5 0 0 5 5 5 3 Type II/IV secretion system protein RNA_helicase PF00910.22 EAX95447.1 - 5.4e-11 42.8 0.8 2.4 8.6 0.0 6.8 6 0 0 6 6 5 2 RNA helicase NACHT PF05729.12 EAX95447.1 - 1.6e-10 41.1 8.3 0.24 11.3 0.1 6.3 6 0 0 6 6 6 4 NACHT domain AAA_29 PF13555.6 EAX95447.1 - 3.5e-10 39.5 2.1 0.2 11.4 0.1 6.0 6 0 0 6 6 5 2 P-loop containing region of AAA domain AAA_19 PF13245.6 EAX95447.1 - 1.2e-09 38.7 2.4 0.082 13.2 0.1 5.6 5 0 0 5 5 5 1 AAA domain Rad17 PF03215.15 EAX95447.1 - 1.3e-09 38.3 0.2 1.4 8.8 0.0 7.0 6 0 0 6 6 6 1 Rad17 P-loop domain RuvB_N PF05496.12 EAX95447.1 - 1.5e-09 37.8 2.3 0.38 10.5 0.0 5.8 6 0 0 6 6 6 3 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EAX95447.1 - 1.8e-09 37.6 0.4 0.033 13.9 0.0 5.5 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_25 PF13481.6 EAX95447.1 - 9.5e-09 35.1 1.7 0.12 12.0 0.0 5.5 5 0 0 5 5 5 2 AAA domain ABC_tran PF00005.27 EAX95447.1 - 3.1e-08 34.2 13.3 0.087 13.3 0.0 6.6 6 1 0 6 6 5 3 ABC transporter Mg_chelatase PF01078.21 EAX95447.1 - 1e-07 31.5 10.2 0.76 9.1 0.2 8.1 7 2 0 7 7 7 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAX95447.1 - 1e-07 32.3 5.5 1.6 9.0 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 EAX95447.1 - 4.2e-07 29.9 4.2 2.2 7.9 0.1 6.2 6 0 0 6 6 5 1 AAA domain PhoH PF02562.16 EAX95447.1 - 1.1e-06 28.3 0.2 0.44 10.0 0.0 4.6 4 0 0 4 4 4 1 PhoH-like protein AAA_8 PF12780.7 EAX95447.1 - 2.9e-06 26.8 1.4 10 5.3 0.0 6.8 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 EAX95447.1 - 3e-06 27.1 0.6 1.2 8.9 0.0 5.3 6 0 0 6 6 4 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EAX95447.1 - 5.7e-06 25.7 0.4 1.3 8.2 0.0 5.6 6 0 0 6 6 6 1 Protein of unknown function (DUF815) MCM PF00493.23 EAX95447.1 - 6.6e-06 25.4 1.1 0.8 8.8 0.0 5.6 7 0 0 7 7 7 1 MCM P-loop domain NTPase_1 PF03266.15 EAX95447.1 - 2.2e-05 24.4 5.1 6.1 6.7 0.2 5.2 4 0 0 4 4 4 0 NTPase Zeta_toxin PF06414.12 EAX95447.1 - 2.4e-05 23.7 1.3 27 3.9 0.0 6.0 6 0 0 6 6 6 0 Zeta toxin TniB PF05621.11 EAX95447.1 - 3.7e-05 23.2 0.1 6 6.2 0.0 5.4 5 0 0 5 5 5 0 Bacterial TniB protein DEAD PF00270.29 EAX95447.1 - 0.00011 22.0 0.2 9.2 6.0 0.0 5.1 4 0 0 4 4 4 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 EAX95447.1 - 0.00012 21.9 0.6 0.32 10.7 0.1 4.7 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EAX95447.1 - 0.00013 22.1 1.5 15 5.8 0.0 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EAX95447.1 - 0.00018 21.4 9.7 0.46 10.2 0.0 6.3 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein TIP49 PF06068.13 EAX95447.1 - 0.00019 20.7 1.2 13 4.9 0.0 5.1 5 0 0 5 5 5 0 TIP49 P-loop domain Roc PF08477.13 EAX95447.1 - 0.00025 21.2 7.4 7.8 6.7 0.0 7.0 7 0 0 7 7 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EAX95447.1 - 0.00053 19.9 3.1 0.93 9.2 0.0 5.7 6 0 0 6 6 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Bac_DnaA PF00308.18 EAX95447.1 - 0.00057 19.8 0.0 7.1 6.4 0.0 4.2 3 0 0 3 3 3 0 Bacterial dnaA protein FtsK_SpoIIIE PF01580.18 EAX95447.1 - 0.0012 18.3 0.7 13 5.0 0.0 4.1 4 0 0 4 4 3 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 EAX95447.1 - 0.0012 18.6 1.6 2.7 7.7 0.0 4.6 5 0 0 5 5 5 1 Cytidylate kinase CPT PF07931.12 EAX95447.1 - 0.0016 18.3 0.9 0.14 11.9 0.0 4.3 4 1 0 4 4 2 1 Chloramphenicol phosphotransferase-like protein SRP54 PF00448.22 EAX95447.1 - 0.0017 18.0 7.6 4.9 6.7 0.0 5.2 6 0 0 6 6 4 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EAX95447.1 - 0.0021 17.5 1.3 1 8.7 0.0 4.6 5 0 0 5 5 4 1 KaiC NB-ARC PF00931.22 EAX95447.1 - 0.0027 16.9 1.1 3.6 6.7 0.0 4.2 4 0 0 4 4 4 0 NB-ARC domain CbiA PF01656.23 EAX95447.1 - 0.0065 16.5 2.7 24 5.0 0.1 4.9 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 EAX95447.1 - 0.011 15.6 11.6 1.3 8.9 0.0 5.6 6 0 0 6 6 4 0 Deoxynucleoside kinase cobW PF02492.19 EAX95447.1 - 0.016 14.8 5.0 16 5.0 0.0 5.2 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain VWA_2 PF13519.6 EAX95447.1 - 0.077 13.7 0.0 0.38 11.4 0.0 2.4 1 0 0 1 1 1 0 von Willebrand factor type A domain CNOT11 PF10155.9 EAX95447.1 - 0.13 12.4 2.1 0.62 10.2 0.8 2.9 2 0 0 2 2 1 0 CCR4-NOT transcription complex subunit 11 AAA_23 PF13476.6 EAX95447.1 - 0.22 12.0 0.0 0.22 12.0 0.0 9.8 9 2 0 9 9 7 0 AAA domain DUF927 PF06048.11 EAX95447.1 - 0.29 10.7 1.1 66 2.9 0.1 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF927) MobB PF03205.14 EAX95447.1 - 8.9 6.2 6.3 27 4.7 0.2 4.2 6 0 0 6 6 3 0 Molybdopterin guanine dinucleotide synthesis protein B Endonuclease_1 PF04231.13 EAX95448.1 - 2.7e-31 109.1 3.8 4e-31 108.5 3.8 1.2 1 0 0 1 1 1 1 Endonuclease I Neuropep_like PF15161.6 EAX95449.1 - 0.0022 17.6 0.1 0.0025 17.5 0.1 1.1 1 0 0 1 1 1 1 Neuropeptide-like BLOC1_2 PF10046.9 EAX95449.1 - 0.004 17.4 0.1 0.0042 17.3 0.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_3 PF13758.6 EAX95449.1 - 0.009 16.0 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Dynamitin PF04912.14 EAX95449.1 - 0.018 14.4 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Dynamitin HSBP1 PF06825.12 EAX95449.1 - 0.021 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 GIT_CC PF16559.5 EAX95449.1 - 0.035 14.0 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran_CTD PF16326.5 EAX95449.1 - 0.054 13.8 0.1 0.066 13.5 0.1 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 EAX95449.1 - 0.1 13.3 0.4 0.12 13.0 0.4 1.2 1 0 0 1 1 1 0 SlyX Nbl1_Borealin_N PF10444.9 EAX95450.1 - 0.048 13.3 9.8 4 7.1 0.0 5.0 2 2 2 4 4 4 0 Nbl1 / Borealin N terminal Pox_A_type_inc PF04508.12 EAX95450.1 - 0.062 13.2 1.8 3.5 7.6 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HSBP1 PF06825.12 EAX95450.1 - 0.076 12.9 13.2 0.38 10.6 1.5 4.4 3 1 1 4 4 4 0 Heat shock factor binding protein 1 Peptidase_M3_N PF08439.10 EAX95450.1 - 0.09 13.1 3.6 8.3 6.8 0.2 3.4 3 0 0 3 3 3 0 Oligopeptidase F DUF2203 PF09969.9 EAX95450.1 - 0.12 13.1 13.9 1.4 9.6 0.1 4.0 1 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Band_7 PF01145.25 EAX95450.1 - 0.37 10.8 5.5 0.45 10.5 3.9 1.7 1 1 0 1 1 1 0 SPFH domain / Band 7 family Retrotrans_gag PF03732.17 EAX95450.1 - 0.57 10.5 11.3 3.3 8.0 0.0 4.5 2 1 0 3 3 3 0 Retrotransposon gag protein Tweety PF04906.13 EAX95450.1 - 0.9 8.1 6.9 0.64 8.6 5.0 1.7 1 1 1 2 2 2 0 Tweety YtxH PF12732.7 EAX95450.1 - 1.3 9.6 8.6 1.1e+02 3.4 5.2 3.8 2 1 0 2 2 2 0 YtxH-like protein DUF4407 PF14362.6 EAX95450.1 - 1.6 8.0 12.0 0.13 11.5 6.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) P16-Arc PF04699.14 EAX95450.1 - 1.8 9.0 7.9 4.2 7.9 0.1 3.1 2 1 1 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Prominin PF05478.11 EAX95450.1 - 3.1 5.6 25.1 0.18 9.7 13.0 2.8 1 1 1 3 3 3 0 Prominin Jnk-SapK_ap_N PF09744.9 EAX95450.1 - 3.7 7.8 22.0 5.2 7.3 2.3 3.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 RP-C_C PF11800.8 EAX95450.1 - 6.5 6.8 9.8 25 4.9 9.8 2.1 1 1 0 1 1 1 0 Replication protein C C-terminal region Lzipper-MIP1 PF14389.6 EAX95451.1 - 0.011 16.0 0.6 0.011 16.0 0.6 3.3 2 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF573 PF04504.14 EAX95451.1 - 0.015 15.9 1.8 0.015 15.9 1.8 4.8 2 1 2 4 4 4 0 Protein of unknown function, DUF573 AhpC-TSA PF00578.21 EAX95451.1 - 0.54 10.2 4.5 0.16 11.9 0.3 2.3 3 0 0 3 3 3 0 AhpC/TSA family MHB PF16525.5 EAX95451.1 - 0.56 10.5 8.4 3.3 8.0 0.1 4.1 2 1 0 4 4 4 0 Haemophore, haem-binding PSP PF04046.16 EAX95452.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95453.1 - 0.027 15.0 2.7 11 7.2 0.2 2.9 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX95454.1 - 0.068 13.6 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX95455.1 - 2e-23 82.2 26.6 3.2e-22 78.3 7.3 4.7 3 2 1 4 4 4 2 Phage tail repeat like PTR PF12789.7 EAX95457.1 - 1.9e-23 82.3 26.4 3.3e-22 78.3 7.3 4.8 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX95457.1 - 0.045 13.5 0.9 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4107 PF13389.6 EAX95458.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX95460.1 - 6.5e-40 137.1 3.8 9.4e-40 136.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX95460.1 - 0.07 12.3 0.1 0.09 11.9 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II KilA-N PF04383.13 EAX95461.1 - 7.7e-43 144.9 0.6 1.6e-42 143.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX95461.1 - 0.005 17.4 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Parathyroid hormone family Glyco_hydro_47 PF01532.20 EAX95462.1 - 1.2e-19 70.6 0.1 1.9e-10 40.3 0.0 3.6 1 1 3 4 4 4 3 Glycosyl hydrolase family 47 DUF2183 PF09949.9 EAX95462.1 - 0.079 13.3 0.6 3.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.18 EAX95463.1 - 1.5e-14 53.2 12.4 1.5e-14 53.2 12.4 1.6 1 1 1 2 2 2 1 Membrane transport protein Amidase02_C PF12123.8 EAX95465.1 - 0.0099 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX95466.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Caskin-tail PF16632.5 EAX95468.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin TMP PF05017.14 EAX95469.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat E2F_TDP PF02319.20 EAX95470.1 - 1.8e-09 37.5 0.1 1.6e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Sel1 PF08238.12 EAX95471.1 - 2.7e-12 46.9 4.1 0.0041 17.8 0.0 7.9 10 0 0 10 10 10 2 Sel1 repeat Pkinase_Tyr PF07714.17 EAX95471.1 - 8.6e-07 28.5 0.0 2.7e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95471.1 - 0.00019 20.9 0.0 0.00054 19.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain TPR_6 PF13174.6 EAX95471.1 - 0.0023 18.4 0.2 3.7 8.4 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Beach PF02138.18 EAX95472.1 - 1.5e-64 218.1 0.4 3.5e-64 216.8 0.4 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX95472.1 - 9.2e-17 61.2 9.8 4.3e-16 59.0 9.8 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAX95472.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH LRR_5 PF13306.6 EAX95473.1 - 8.2e-54 181.0 47.5 9.6e-21 74.1 13.6 4.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95473.1 - 3.1e-12 46.1 6.6 2.9e-06 27.0 0.1 6.6 2 2 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EAX95473.1 - 0.74 10.3 14.1 2.2 8.9 0.2 5.2 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) MscL PF01741.18 EAX95474.1 - 0.071 13.4 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF1206 PF06724.11 EAX95474.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DPM2 PF07297.12 EAX95474.1 - 0.13 12.6 0.2 3.4 8.0 0.1 2.9 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4625 PF15418.6 EAX95474.1 - 5.4 7.3 26.6 0.82 9.9 0.1 7.2 6 2 2 8 8 8 0 Domain of unknown function (DUF4625) PSP PF04046.16 EAX95475.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95476.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX95477.1 - 0.043 14.3 0.8 0.09 13.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX95478.1 - 6.9e-34 115.7 19.3 1.8e-33 114.4 15.3 4.4 4 2 1 5 5 5 2 Phage tail repeat like DUF4057 PF13266.6 EAX95478.1 - 0.021 14.6 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) DUF4116 PF13475.6 EAX95478.1 - 0.034 13.9 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX95478.1 - 0.15 12.3 2.7 0.36 11.1 0.1 2.7 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain Beta_helix PF13229.6 EAX95479.1 - 8.5e-28 97.2 54.6 1.1e-13 51.3 16.8 4.9 2 1 1 4 4 4 4 Right handed beta helix region NosD PF05048.13 EAX95479.1 - 7.4e-12 45.0 41.3 1.2e-08 34.6 13.4 3.8 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EAX95479.1 - 2.6e-09 37.2 32.7 0.0016 18.3 5.6 4.5 2 1 1 3 3 3 3 Pectate lyase superfamily protein TPR_12 PF13424.6 EAX95480.1 - 2e-07 31.2 12.1 0.00012 22.3 3.5 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAX95480.1 - 4e-06 26.5 10.3 0.058 13.5 2.9 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAX95480.1 - 5.7e-05 22.8 12.0 0.008 16.0 3.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX95480.1 - 0.00013 21.8 10.4 0.35 11.2 2.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAX95480.1 - 0.0084 16.0 2.3 0.041 13.8 0.3 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAX95480.1 - 0.043 14.5 4.6 28 5.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EAX95480.1 - 0.097 12.7 0.7 0.097 12.7 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAX95480.1 - 0.15 12.1 5.8 0.78 9.9 0.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 EAX95481.1 - 8.8e-35 118.6 4.0 1.8e-07 31.6 0.0 7.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95481.1 - 2.2e-31 108.3 15.4 8.7e-14 51.9 0.2 5.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95481.1 - 6.2e-28 96.0 4.5 1.8e-05 25.0 0.4 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX95481.1 - 2.3e-23 81.9 2.6 4.6e-06 26.8 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95481.1 - 3e-23 79.4 8.7 0.0013 19.0 0.1 9.4 11 0 0 11 11 11 5 Ankyrin repeat DUF3447 PF11929.8 EAX95481.1 - 3.6e-19 68.5 22.2 5.5e-19 67.9 1.3 5.6 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) HrcA PF01628.21 EAX95481.1 - 0.097 12.6 1.6 1.4 8.8 0.3 2.5 3 0 0 3 3 3 0 HrcA protein C terminal domain DUF3240 PF11582.8 EAX95481.1 - 0.13 12.5 0.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) DUF563 PF04577.14 EAX95482.1 - 8.1e-20 71.9 0.0 9.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ras PF00071.22 EAX95483.1 - 4.5e-46 156.4 0.0 5.2e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95483.1 - 5.4e-30 104.1 0.0 7.6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95483.1 - 1.9e-16 60.0 0.0 2.4e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX95483.1 - 2.8e-05 23.7 0.0 9.2e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX95483.1 - 3.4e-05 23.9 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX95483.1 - 0.00028 20.3 0.0 0.00036 20.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX95483.1 - 0.00073 19.3 0.0 0.0049 16.6 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAX95483.1 - 0.00081 18.9 0.0 0.0084 15.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAX95483.1 - 0.0011 18.9 0.0 1.6 8.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAX95483.1 - 0.023 13.9 0.3 2 7.5 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 EAX95483.1 - 0.04 14.3 0.0 0.072 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EAX95483.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 EAX95483.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain VHS PF00790.19 EAX95484.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.7 1 1 1 2 2 2 1 VHS domain Ras PF00071.22 EAX95485.1 - 1.3e-24 86.6 0.1 1.4e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95485.1 - 8.1e-15 55.1 0.0 8.8e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95485.1 - 1.6e-05 24.5 0.0 1.7e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX95485.1 - 0.0087 15.5 0.0 0.0099 15.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX95485.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4809 PF16067.5 EAX95486.1 - 0.057 13.6 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) PUF PF00806.19 EAX95487.1 - 2.9e-44 146.3 13.3 2.2e-06 27.0 0.0 8.3 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat CPL PF08144.11 EAX95487.1 - 0.00036 20.9 5.0 0.98 9.8 0.0 4.6 1 1 3 4 4 4 2 CPL (NUC119) domain DUF445 PF04286.12 EAX95487.1 - 0.0091 15.8 1.3 0.019 14.8 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF445) Utp13 PF08625.11 EAX95487.1 - 0.034 14.1 0.6 4 7.3 0.2 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain NPC1_N PF16414.5 EAX95487.1 - 0.083 12.4 1.0 0.14 11.7 1.0 1.3 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus FWWh PF14922.6 EAX95487.1 - 0.098 12.6 2.4 0.43 10.5 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function Acyl-CoA_dh_N PF02771.16 EAX95487.1 - 0.16 12.7 0.0 41 4.9 0.0 2.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain YpjP PF14005.6 EAX95487.1 - 0.16 12.0 2.8 2.6 8.1 0.0 3.3 2 1 0 3 3 3 0 YpjP-like protein CLASP_N PF12348.8 EAX95487.1 - 0.25 10.8 3.7 4.3 6.8 0.3 3.4 1 1 2 3 3 3 0 CLASP N terminal ARL2_Bind_BART PF11527.8 EAX95487.1 - 7.8 6.6 9.9 3.6 7.7 0.3 3.5 2 1 1 3 3 3 0 The ARF-like 2 binding protein BART RhoGEF PF00621.20 EAX95488.1 - 1.3e-32 113.5 4.1 1.3e-32 113.5 4.1 2.1 3 0 0 3 3 3 1 RhoGEF domain Kelch_4 PF13418.6 EAX95488.1 - 2.6e-27 94.6 1.4 1.6e-08 34.4 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX95488.1 - 1.5e-23 82.3 3.8 4.5e-06 26.8 0.0 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EAX95488.1 - 9.2e-22 76.6 1.0 1.7e-05 24.7 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EAX95488.1 - 2.1e-15 56.6 0.3 0.00045 20.4 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX95488.1 - 6.2e-15 54.5 4.4 0.0001 21.8 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EAX95488.1 - 1.7e-11 43.6 1.9 0.014 15.3 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Tli4_N PF18443.1 EAX95488.1 - 0.0017 18.8 0.1 0.0079 16.6 0.1 2.2 1 0 0 1 1 1 1 Tle cognate immunity protein 4 N-terminal domain Mis12 PF05859.12 EAX95489.1 - 4.1e-14 52.8 0.6 4.1e-14 52.8 0.6 2.2 2 0 0 2 2 2 1 Mis12 protein Mod_r PF07200.13 EAX95489.1 - 0.0012 18.9 1.4 0.0012 18.9 1.4 2.7 2 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein Med9 PF07544.13 EAX95489.1 - 0.013 15.6 11.6 0.056 13.5 0.4 4.0 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF4351 PF14261.6 EAX95489.1 - 0.04 14.0 1.0 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DUF883 PF05957.13 EAX95489.1 - 0.054 14.1 3.8 9.1 7.0 0.3 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 EAX95489.1 - 0.1 12.7 10.4 0.32 11.1 6.4 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Peptidase_M16 PF00675.20 EAX95489.1 - 0.13 12.3 2.4 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF948 PF06103.11 EAX95489.1 - 0.15 12.3 3.1 2.8 8.3 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 EAX95489.1 - 0.19 12.3 1.4 8.7 7.0 0.3 3.1 2 1 0 2 2 2 0 YtxH-like protein DUF3418 PF11898.8 EAX95489.1 - 0.19 10.4 4.8 0.092 11.4 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3418) HisKA PF00512.25 EAX95489.1 - 0.64 10.1 3.3 1.4 9.0 0.2 2.9 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Exonuc_VII_L PF02601.15 EAX95489.1 - 2.2 7.8 9.4 2.2 7.8 0.3 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF5102 PF17104.5 EAX95489.1 - 2.6 8.0 8.9 2.7 8.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) B56 PF01603.20 EAX95490.1 - 2.7e-77 260.5 14.2 3.4e-77 260.2 14.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ATPase PF06745.13 EAX95490.1 - 0.16 11.3 0.1 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 KaiC HTH_ParB PF17762.1 EAX95491.1 - 0.095 12.5 3.4 0.22 11.4 2.6 2.1 2 0 0 2 2 2 0 HTH domain found in ParB protein FAD-oxidase_C PF02913.19 EAX95491.1 - 0.1 12.2 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain IPK PF03770.16 EAX95491.1 - 0.34 10.7 3.0 0.54 10.1 3.0 1.3 1 1 0 1 1 1 0 Inositol polyphosphate kinase TIP120 PF08623.10 EAX95492.1 - 0.032 14.0 0.8 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF4203 PF13886.6 EAX95492.1 - 0.06 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) MMS19_C PF12460.8 EAX95492.1 - 1.4 7.9 8.8 0.25 10.4 4.1 2.2 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal LRR_6 PF13516.6 EAX95493.1 - 1.4e-10 40.3 13.1 0.5 10.5 0.0 9.0 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EAX95493.1 - 0.0001 22.3 7.1 30 5.7 0.0 7.2 7 0 0 7 7 7 1 Leucine Rich Repeat DHquinase_II PF01220.19 EAX95493.1 - 0.12 12.1 0.1 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Dehydroquinase class II GrpE PF01025.19 EAX95493.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 GrpE Ribosomal_S30 PF04758.14 EAX95494.1 - 5.5e-26 90.5 3.6 6.1e-26 90.4 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 PNP_UDP_1 PF01048.20 EAX95495.1 - 4.8e-28 98.0 0.2 4.9e-27 94.7 0.1 2.6 2 0 0 2 2 2 1 Phosphorylase superfamily Gly-zipper_Omp PF13488.6 EAX95496.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAX95496.1 - 0.23 10.7 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX95496.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX95496.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Sigma_reg_N PF13800.6 EAX95498.1 - 0.027 14.7 0.1 0.035 14.4 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Amnionless PF14828.6 EAX95498.1 - 0.031 13.1 0.0 0.034 13.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless LapA_dom PF06305.11 EAX95498.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UBA PF00627.31 EAX95501.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain PGM_PMM_I PF02878.16 EAX95504.1 - 9.8e-41 138.7 0.1 2.5e-40 137.4 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EAX95504.1 - 8.9e-24 84.1 0.0 2.9e-23 82.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EAX95504.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EAX95504.1 - 9.1e-06 25.8 0.0 2.8e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DDE_1 PF03184.19 EAX95505.1 - 5.8e-14 52.1 0.1 8.3e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rRNA_methylase PF06962.12 EAX95505.1 - 0.0047 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Putative rRNA methylase NCKAP5 PF15246.6 EAX95506.1 - 0.17 11.4 7.9 0.16 11.5 7.9 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Tnp_22_trimer PF17489.2 EAX95506.1 - 0.37 10.8 10.0 1.1 9.3 1.8 2.3 1 1 1 2 2 2 0 L1 transposable element trimerization domain Orf78 PF06024.12 EAX95511.1 - 0.0016 18.7 0.5 0.0016 18.7 0.5 1.7 2 0 0 2 2 2 1 Orf78 (ac78) DUF2207 PF09972.9 EAX95511.1 - 0.043 12.6 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3377 PF11857.8 EAX95511.1 - 0.047 13.6 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cadherin_C_2 PF16492.5 EAX95511.1 - 0.051 14.3 0.0 0.087 13.6 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MRAP PF15183.6 EAX95511.1 - 8.6 6.4 9.3 17 5.5 1.0 2.6 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF4107 PF13389.6 EAX95513.1 - 6.7e-72 240.9 3.4 8.8e-72 240.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX95514.1 - 2.7e-153 508.3 13.6 3.4e-153 508.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX95514.1 - 0.65 10.5 4.3 1.9 9.0 0.4 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX95514.1 - 1.7 9.0 3.9 1.5 9.2 1.1 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Pkinase PF00069.25 EAX95515.1 - 1.6e-69 234.2 0.9 2.4e-69 233.6 0.9 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95515.1 - 3e-38 131.6 0.0 4.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95515.1 - 1.2e-08 34.7 0.0 3.5e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX95515.1 - 0.0014 17.6 0.6 0.0014 17.6 0.6 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Amnionless PF14828.6 EAX95516.1 - 0.0042 16.0 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Amnionless DUF4064 PF13273.6 EAX95516.1 - 0.0057 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Stevor PF17410.2 EAX95516.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 EAX95516.1 - 0.015 16.1 0.0 0.028 15.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAX95516.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family Polysacc_lyase PF14099.6 EAX95516.1 - 0.056 13.3 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Cadherin_C_2 PF16492.5 EAX95516.1 - 0.077 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal SCF PF02404.15 EAX95516.1 - 0.1 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor Sarcoglycan_2 PF05510.13 EAX95516.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF4625 PF15418.6 EAX95517.1 - 3.2e-08 33.9 2.0 0.0062 16.8 0.1 5.4 3 1 1 4 4 4 2 Domain of unknown function (DUF4625) I-set PF07679.16 EAX95517.1 - 0.027 14.5 0.1 4.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain He_PIG PF05345.12 EAX95517.1 - 0.033 14.4 0.3 9 6.6 0.0 3.0 2 0 0 2 2 2 0 Putative Ig domain CotE PF10628.9 EAX95517.1 - 0.67 9.6 4.7 7.2 6.2 0.4 3.3 3 1 1 4 4 4 0 Outer spore coat protein E (CotE) DUF4265 PF14085.6 EAX95518.1 - 0.012 15.5 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Big_7 PF17957.1 EAX95518.1 - 0.045 14.5 23.7 0.18 12.6 0.3 6.2 7 0 0 7 7 7 0 Bacterial Ig domain Gly-zipper_Omp PF13488.6 EAX95520.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX95520.1 - 0.31 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX95520.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Beach PF02138.18 EAX95522.1 - 1.1e-100 336.6 1.4 3.9e-100 334.8 0.2 2.5 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 EAX95522.1 - 4.5e-12 45.8 4.6 4.5e-12 45.8 4.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) WD40 PF00400.32 EAX95522.1 - 0.00024 21.8 0.8 0.0028 18.5 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat PHP PF02811.19 EAX95525.1 - 0.091 13.1 0.5 0.14 12.4 0.5 1.3 1 0 0 1 1 1 0 PHP domain Caprin-1_dimer PF18293.1 EAX95525.1 - 0.12 12.8 10.3 0.048 14.2 2.5 2.7 2 0 0 2 2 2 0 Caprin-1 dimerization domain Ank_2 PF12796.7 EAX95526.1 - 1.3e-33 115.4 9.1 1.5e-15 57.5 0.6 6.2 2 1 6 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95526.1 - 1.8e-25 89.0 4.8 1.1e-07 32.2 0.0 6.8 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95526.1 - 4.2e-23 78.9 9.6 0.00088 19.6 0.0 9.4 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EAX95526.1 - 1.7e-22 79.1 2.4 4.2e-07 30.1 0.0 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX95526.1 - 1.6e-15 56.7 7.2 0.0008 19.7 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 EAX95526.1 - 3.1e-09 36.7 2.4 0.00052 19.9 0.4 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) ETRAMP PF09716.10 EAX95527.1 - 0.043 13.9 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) KilA-N PF04383.13 EAX95529.1 - 5.6e-42 142.1 0.2 1.4e-41 140.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX95529.1 - 0.014 16.0 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family DUF1340 PF07067.11 EAX95530.1 - 0.054 12.9 0.3 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Amidohydro_3 PF07969.11 EAX95531.1 - 1.6e-77 262.0 0.0 1.8e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EAX95531.1 - 4.4e-09 36.1 0.0 1.3e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family DUF5490 PF17593.2 EAX95531.1 - 0.13 12.2 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Amidohydro_3 PF07969.11 EAX95532.1 - 2e-07 30.9 0.0 2.2e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Glyco_hydro_31 PF01055.26 EAX95533.1 - 9.5e-118 394.1 3.9 9.5e-118 394.1 3.9 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAX95533.1 - 1.5e-14 54.1 0.2 6.3e-14 52.0 0.2 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EAX95533.1 - 0.0025 18.0 0.3 0.016 15.5 0.3 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF2773 PF10971.8 EAX95533.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) F5_F8_type_C PF00754.25 EAX95534.1 - 1.2e-06 28.7 0.3 2.1e-05 24.7 0.0 2.5 3 0 0 3 3 3 1 F5/8 type C domain LRR_5 PF13306.6 EAX95535.1 - 9.5e-12 45.0 4.6 9.4e-06 25.6 1.1 2.4 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) AcetylCoA_hydro PF02550.15 EAX95535.1 - 0.028 14.4 0.0 0.073 13.0 0.0 1.6 1 1 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain F5_F8_type_C PF00754.25 EAX95536.1 - 3.7e-06 27.1 0.0 5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain UDPG_MGDP_dh PF00984.19 EAX95536.1 - 0.11 12.6 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain LRR_5 PF13306.6 EAX95537.1 - 1e-13 51.4 10.5 6.1e-07 29.4 3.3 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) F5_F8_type_C PF00754.25 EAX95538.1 - 4.7e-06 26.7 0.0 8.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX95539.1 - 8e-06 26.0 0.0 2.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain Myb_DNA-binding PF00249.31 EAX95540.1 - 3e-32 110.6 1.8 4.7e-17 61.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95540.1 - 7.1e-29 99.8 5.5 1.1e-19 70.5 1.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95540.1 - 2.1e-09 37.4 0.7 9.8e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95540.1 - 6.9e-07 29.1 3.3 1.3e-05 25.0 0.5 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX95540.1 - 0.00053 20.1 3.4 0.017 15.3 0.9 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EAX95540.1 - 0.00059 19.9 6.3 0.97 9.6 0.0 3.5 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain HTH_32 PF13565.6 EAX95540.1 - 0.00085 19.9 0.2 1.4 9.6 0.0 3.1 2 1 1 3 3 3 1 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 EAX95540.1 - 0.0016 18.8 5.2 0.055 13.9 0.5 3.0 2 2 0 2 2 2 2 Myb/SANT-like DNA-binding domain Poxvirus_B22R_N PF13169.6 EAX95540.1 - 0.052 14.0 0.4 0.12 12.9 0.4 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal AbbA_antirepres PF14156.6 EAX95540.1 - 0.052 13.4 0.5 7.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Antirepressor AbbA Adeno_E3_15_3 PF03307.14 EAX95541.1 - 0.028 14.4 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region T2SSF PF00482.23 EAX95541.1 - 0.53 10.2 4.9 0.29 11.1 1.1 2.5 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F ApoO PF09769.9 EAX95541.1 - 2.7 8.0 13.3 1.2 9.1 0.6 4.3 4 2 0 4 4 4 0 Apolipoprotein O DUF2935 PF11155.8 EAX95541.1 - 4.6 7.6 14.1 1.4e+02 2.8 0.5 4.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Phasin PF05597.11 EAX95542.1 - 0.032 14.2 0.0 8.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) UBA_3 PF09288.10 EAX95542.1 - 0.11 12.3 0.0 17 5.3 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Sec31 PF11549.8 EAX95542.1 - 0.17 11.8 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein transport protein SEC31 DUF2207 PF09972.9 EAX95543.1 - 0.0045 15.8 0.6 0.0067 15.3 0.6 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Baculo_PEP_C PF04513.12 EAX95543.1 - 0.084 12.9 9.9 2.7 8.0 0.2 3.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EAX95543.1 - 0.12 12.5 8.2 0.33 11.0 3.9 3.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) FA_desaturase PF00487.24 EAX95543.1 - 0.18 11.6 0.3 0.26 11.1 0.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase HMG_box PF00505.19 EAX95544.1 - 8.4e-13 48.5 0.3 1.2e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX95544.1 - 8.3e-11 42.3 0.2 1.1e-10 41.9 0.2 1.2 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 EAX95544.1 - 0.046 13.9 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Protamine and protamine like DUF3021 PF11457.8 EAX95545.1 - 0.02 15.2 0.5 0.051 13.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Pilin_N PF07790.11 EAX95545.1 - 0.1 13.5 2.3 1.4 9.9 0.3 2.7 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal Ank_2 PF12796.7 EAX95546.1 - 2.1e-44 150.0 27.2 9.6e-19 67.8 0.3 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95546.1 - 5.9e-36 122.4 8.7 5.6e-10 39.5 0.0 7.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95546.1 - 1.9e-32 110.9 3.2 2.4e-09 37.3 0.1 6.9 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95546.1 - 2.8e-28 94.8 5.3 2.2e-05 24.5 0.1 8.5 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EAX95546.1 - 8.7e-24 82.9 5.5 2.3e-06 27.8 0.1 6.9 7 0 0 7 7 7 4 Ankyrin repeat SWIB PF02201.18 EAX95546.1 - 0.041 13.8 1.5 2 8.4 0.2 2.7 2 0 0 2 2 2 0 SWIB/MDM2 domain DUF3447 PF11929.8 EAX95546.1 - 0.048 13.6 6.8 0.52 10.3 0.8 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) DUF3671 PF12420.8 EAX95547.1 - 0.0047 17.0 0.8 0.017 15.2 0.8 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF3377 PF11857.8 EAX95547.1 - 0.0054 16.6 0.6 0.013 15.4 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 EAX95547.1 - 0.02 14.8 1.4 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family ODV-E18 PF10717.9 EAX95547.1 - 0.033 14.1 0.7 0.082 12.8 0.7 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.6 EAX95547.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5383 PF17355.2 EAX95547.1 - 0.081 13.3 0.1 0.081 13.3 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5383) ASFV_J13L PF05568.11 EAX95547.1 - 0.083 12.6 0.8 0.19 11.5 0.8 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 EAX95547.1 - 0.17 12.8 0.7 0.17 12.8 0.7 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 EAX95547.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.2 3 0 0 3 3 3 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 EAX95547.1 - 0.28 10.8 3.7 0.63 9.7 3.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2207 PF09972.9 EAX95547.1 - 0.47 9.2 7.9 1.6 7.4 7.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LRRC37AB_C PF14914.6 EAX95547.1 - 0.63 9.9 8.4 0.13 12.2 0.6 2.4 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SP_C-Propep PF08999.10 EAX95547.1 - 2.9 7.8 5.4 5.5 6.8 5.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ECSCR PF15820.5 EAX95547.1 - 5 7.0 9.0 5.9 6.8 7.8 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 EAX95547.1 - 9.4 6.0 12.4 8.8 6.1 9.7 1.9 1 1 1 2 2 2 0 Rifin DUF3671 PF12420.8 EAX95548.1 - 0.0047 17.0 0.8 0.017 15.2 0.8 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF3377 PF11857.8 EAX95548.1 - 0.0054 16.6 0.6 0.013 15.4 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 EAX95548.1 - 0.02 14.8 1.4 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family ODV-E18 PF10717.9 EAX95548.1 - 0.033 14.1 0.7 0.082 12.8 0.7 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.6 EAX95548.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5383 PF17355.2 EAX95548.1 - 0.081 13.3 0.1 0.081 13.3 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5383) ASFV_J13L PF05568.11 EAX95548.1 - 0.083 12.6 0.8 0.19 11.5 0.8 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 EAX95548.1 - 0.17 12.8 0.7 0.17 12.8 0.7 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 EAX95548.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.2 3 0 0 3 3 3 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 EAX95548.1 - 0.28 10.8 3.7 0.63 9.7 3.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2207 PF09972.9 EAX95548.1 - 0.47 9.2 7.9 1.6 7.4 7.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LRRC37AB_C PF14914.6 EAX95548.1 - 0.63 9.9 8.4 0.13 12.2 0.6 2.4 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SP_C-Propep PF08999.10 EAX95548.1 - 2.9 7.8 5.4 5.5 6.8 5.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ECSCR PF15820.5 EAX95548.1 - 5 7.0 9.0 5.9 6.8 7.8 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 EAX95548.1 - 9.4 6.0 12.4 8.8 6.1 9.7 1.9 1 1 1 2 2 2 0 Rifin Pribosyltran_N PF13793.6 EAX95549.1 - 7.9e-13 48.4 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EAX95549.1 - 3.8e-07 30.3 0.2 1.2e-06 28.7 0.2 1.6 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EAX95549.1 - 0.00059 19.4 0.0 0.00093 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ArfGap PF01412.18 EAX95550.1 - 5.7e-36 123.1 0.1 9e-36 122.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CofC PF01983.16 EAX95550.1 - 0.0076 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Guanylyl transferase CofC like TPR_11 PF13414.6 EAX95551.1 - 2.4e-13 49.5 0.8 0.0016 18.1 0.2 6.1 7 0 0 7 7 7 2 TPR repeat TPR_14 PF13428.6 EAX95551.1 - 3.2e-12 46.2 0.3 0.012 16.4 0.0 6.9 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAX95551.1 - 1e-10 42.0 5.2 2.6 8.6 0.0 7.5 8 1 0 8 8 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAX95551.1 - 1.7e-09 37.1 19.0 0.59 10.4 0.2 10.8 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX95551.1 - 4.3e-09 35.8 13.5 0.49 10.3 0.1 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX95551.1 - 9.5e-09 35.1 6.9 1.1 9.8 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAX95551.1 - 1.3e-08 35.3 0.0 0.39 11.4 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX95551.1 - 1.9e-08 34.5 2.9 0.77 10.1 0.0 6.5 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX95551.1 - 8.2e-08 31.9 25.0 2.1 8.8 0.1 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAX95551.1 - 2.7e-06 27.7 7.9 0.1 13.2 0.2 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX95551.1 - 0.00036 20.3 0.4 41 4.5 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAX95551.1 - 0.0012 19.0 0.0 0.41 10.8 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAX95551.1 - 0.0087 16.1 1.9 9.8 6.3 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EAX95551.1 - 0.0088 15.9 1.8 2 8.4 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat hnRNP_Q_AcD PF18360.1 EAX95551.1 - 0.038 14.0 0.1 0.15 12.0 0.1 2.1 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain BTAD PF03704.17 EAX95551.1 - 0.048 14.1 0.0 21 5.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 EAX95551.1 - 0.055 13.4 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 EAX95551.1 - 0.18 12.1 23.1 3.7 7.8 0.1 8.4 9 1 1 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 EAX95551.1 - 0.72 9.9 24.0 0.14 12.1 1.2 6.3 7 1 0 7 7 6 0 Putative TPR-like repeat EF-hand_6 PF13405.6 EAX95552.1 - 4e-15 54.4 6.5 0.31 11.1 0.0 8.2 8 0 0 8 8 8 5 EF-hand domain EF-hand_1 PF00036.32 EAX95552.1 - 1.3e-08 33.8 0.4 0.22 11.2 0.0 6.4 7 0 0 7 7 7 3 EF hand EF-hand_7 PF13499.6 EAX95552.1 - 2.6e-07 31.0 13.5 5.8 7.4 0.0 7.4 7 0 0 7 7 7 3 EF-hand domain pair DUF5580 PF17743.1 EAX95552.1 - 0.0072 14.9 0.4 0.22 10.0 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5580) DUF2087 PF09860.9 EAX95552.1 - 0.031 14.4 0.1 0.13 12.4 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) RST PF12174.8 EAX95552.1 - 0.056 13.4 2.7 9.2 6.3 0.1 4.8 4 1 1 5 5 5 0 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 EAX95552.1 - 0.059 14.3 18.2 9.3 7.2 0.2 6.5 7 0 0 7 7 7 0 EF-hand domain TPR_14 PF13428.6 EAX95553.1 - 6.4e-14 51.5 3.1 0.0014 19.2 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat PRP1_N PF06424.12 EAX95553.1 - 1.3e-12 48.3 21.9 2.6e-09 37.6 4.5 3.5 2 1 1 3 3 3 2 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EAX95553.1 - 2e-05 25.0 4.4 0.0045 17.5 0.4 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAX95553.1 - 0.00025 20.9 0.2 0.2 11.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX95553.1 - 0.00037 20.7 0.4 0.088 13.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAX95553.1 - 0.052 13.7 0.1 0.31 11.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 EAX95554.1 - 7.3e-16 58.3 4.3 0.00028 21.6 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 EAX95554.1 - 1.5e-08 34.4 11.7 0.0049 16.2 0.0 4.4 2 2 2 4 4 4 4 WD40-like domain ANAPC4_WD40 PF12894.7 EAX95554.1 - 1.9e-05 24.9 0.6 2.6 8.4 0.1 5.0 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EAX95554.1 - 4.9 6.8 7.9 1.3 8.7 0.1 3.4 3 2 1 4 4 4 0 TUP1-like enhancer of split B56 PF01603.20 EAX95555.1 - 4.7e-88 295.9 27.1 5.8e-88 295.6 27.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LMBR1 PF04791.16 EAX95556.1 - 7.8 5.3 6.5 9.4 5.0 6.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FOP_dimer PF09398.10 EAX95557.1 - 0.003 17.8 0.1 0.0072 16.5 0.1 1.6 1 1 1 2 2 2 1 FOP N terminal dimerisation domain HAD_2 PF13419.6 EAX95558.1 - 3.7e-24 85.8 0.1 5.1e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX95558.1 - 2.4e-16 60.7 0.6 3.2e-14 53.7 0.6 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX95558.1 - 0.0002 21.3 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAX95558.1 - 0.0025 17.9 0.0 2.2 8.4 0.0 3.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 EAX95559.1 - 1e-38 131.8 0.0 4.8e-13 49.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95559.1 - 1.5e-35 120.1 0.0 8.9e-06 25.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX95559.1 - 2.2e-31 107.5 0.1 2.8e-06 27.5 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95559.1 - 2.8e-28 97.9 0.0 8.1e-10 39.0 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95559.1 - 2.3e-25 85.9 0.0 0.006 17.0 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat DUF1897 PF09005.10 EAX95559.1 - 0.01 15.3 0.0 52 3.4 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) SnAPC_2_like PF11035.8 EAX95559.1 - 0.033 14.3 0.4 0.045 13.9 0.4 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb TruB_N PF01509.18 EAX95559.1 - 0.44 10.9 2.3 3.5 8.0 0.0 2.2 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) Choline_transpo PF04515.12 EAX95560.1 - 2.2e-93 313.0 34.8 2.2e-93 313.0 34.8 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter Zip PF02535.22 EAX95560.1 - 2.1 7.5 10.2 0.22 10.7 0.9 2.8 2 0 0 2 2 2 0 ZIP Zinc transporter NPR3 PF03666.13 EAX95560.1 - 2.2 7.0 5.0 3.2 6.4 5.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 EAX95560.1 - 2.9 6.2 5.9 3.9 5.8 5.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ribosomal_L37e PF01907.19 EAX95561.1 - 2.8e-25 88.2 9.4 3.9e-25 87.8 9.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 EAX95561.1 - 0.089 12.8 2.3 0.14 12.2 2.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 EAX95561.1 - 2.2 7.8 6.6 10 5.7 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) DUF1510 PF07423.11 EAX95562.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) ARA70 PF12489.8 EAX95563.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX95564.1 - 6.9e-05 22.4 3.3 7e-05 22.4 2.0 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX95564.1 - 0.0059 16.6 1.2 0.012 15.7 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX95564.1 - 0.015 14.8 0.2 0.033 13.7 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX95564.1 - 0.036 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 PH_3 PF14593.6 EAX95566.1 - 0.089 12.9 0.7 5.6 7.1 0.1 3.3 3 0 0 3 3 3 0 PH domain DUF4795 PF16043.5 EAX95566.1 - 0.13 11.8 14.3 0.43 10.2 1.4 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAX95566.1 - 8 6.9 13.6 0.14 12.4 0.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1947) DUF3839 PF12943.7 EAX95567.1 - 1.1e-153 509.7 13.0 1.4e-153 509.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) APC_u14 PF16635.5 EAX95567.1 - 0.73 10.4 4.0 0.62 10.6 1.6 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr KELK PF15796.5 EAX95567.1 - 4.7 7.7 7.8 1.9 9.0 0.6 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 EAX95568.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.8 EAX95568.1 - 0.071 12.3 2.2 0.079 12.1 2.2 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PaRep2a PF07903.11 EAX95568.1 - 0.076 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX95568.1 - 6.3 6.8 12.1 0.18 11.7 2.9 2.6 4 0 0 4 4 4 0 Spo12 family T5orf172 PF10544.9 EAX95569.1 - 4.2e-07 30.4 0.3 8.5e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX95570.1 - 5.2e-35 119.7 0.6 5.2e-35 119.7 0.6 1.9 2 0 0 2 2 2 1 KilA-N domain Cep57_MT_bd PF06657.13 EAX95570.1 - 0.52 10.8 8.5 9.1 6.8 3.5 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX95571.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX95571.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX95571.1 - 4.8e-05 23.2 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX95571.1 - 0.00011 22.3 2.8 0.00028 21.0 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX95571.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX95571.1 - 0.0011 18.8 0.6 0.002 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX95571.1 - 0.0012 18.5 0.4 0.0095 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX95571.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX95571.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX95571.1 - 0.088 13.2 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX95571.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX95571.1 - 0.39 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX95572.1 - 0.37 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX95573.1 - 9.9e-64 213.6 6.4 1.1e-63 213.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) IBN_N PF03810.19 EAX95574.1 - 0.002 18.0 6.8 0.071 13.0 0.4 4.0 3 1 1 4 4 4 2 Importin-beta N-terminal domain Cnd1 PF12717.7 EAX95574.1 - 0.044 13.8 0.4 0.044 13.8 0.4 5.9 4 2 3 7 7 7 0 non-SMC mitotic condensation complex subunit 1 ApoC-I PF04691.12 EAX95575.1 - 0.085 12.8 9.3 3 7.8 0.2 4.6 3 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) YtxH PF12732.7 EAX95575.1 - 0.1 13.2 17.7 1.4 9.5 0.4 5.5 3 2 0 3 3 3 0 YtxH-like protein DUF3584 PF12128.8 EAX95575.1 - 0.44 8.0 31.5 0.095 10.2 11.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3584) Shugoshin_N PF07558.11 EAX95575.1 - 0.87 9.5 8.2 10 6.1 0.7 3.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region LPP PF04728.13 EAX95575.1 - 1.6 9.2 0.0 1.6 9.2 0.0 8.6 10 1 1 11 11 11 0 Lipoprotein leucine-zipper DUF1542 PF07564.11 EAX95575.1 - 1.7 8.8 15.7 0.55 10.4 2.9 3.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) ApoO PF09769.9 EAX95575.1 - 2 8.4 5.2 16 5.5 0.2 4.3 3 2 0 4 4 4 0 Apolipoprotein O MtrG PF04210.13 EAX95575.1 - 2.1 8.3 4.9 26 4.7 0.3 4.2 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1192 PF06698.11 EAX95575.1 - 2.9 8.0 7.7 25 5.0 0.5 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.10 EAX95575.1 - 7 6.8 43.1 0.26 11.5 3.5 6.2 4 2 2 7 7 7 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 EAX95575.1 - 7.2 6.7 25.0 0.37 10.9 0.1 6.4 5 2 3 8 8 8 0 Protein of unknown function (DUF1515) SOAR PF16533.5 EAX95575.1 - 9.1 6.3 13.9 7.7 6.6 0.6 4.7 4 0 0 4 4 4 0 STIM1 Orai1-activating region WXG100 PF06013.12 EAX95575.1 - 9.6 6.5 17.8 8.8 6.6 0.1 6.5 6 2 1 7 7 7 0 Proteins of 100 residues with WXG Myosin_TH1 PF06017.13 EAX95576.1 - 2.6e-05 24.0 0.3 4.4e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding LRR_6 PF13516.6 EAX95576.1 - 0.0033 17.4 4.2 0.92 9.7 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat DUF1818 PF08848.11 EAX95577.1 - 0.032 14.3 0.3 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1818) Ribosomal_L37ae PF01780.19 EAX95578.1 - 2.5e-39 133.2 8.4 2.9e-39 133.0 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Lar_restr_allev PF14354.6 EAX95578.1 - 0.0077 16.6 0.8 0.013 15.8 0.8 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-RING_13 PF17977.1 EAX95578.1 - 0.019 15.1 2.6 0.033 14.3 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 EAX95578.1 - 0.026 14.9 1.9 3.3 8.3 0.3 2.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF2175 PF09943.9 EAX95578.1 - 0.071 13.4 0.5 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf_UBZ PF18439.1 EAX95578.1 - 0.22 11.2 1.4 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 EAX95578.1 - 0.25 11.4 3.9 3.7 7.6 4.4 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 EAX95578.1 - 3.9 7.6 7.3 4.9 7.3 0.3 2.5 2 1 1 3 3 3 0 BED zinc finger Gly_rich PF12810.7 EAX95579.1 - 4.3e-43 148.0 33.5 5.2e-43 147.7 33.5 1.0 1 0 0 1 1 1 1 Glycine rich protein XRN_N PF03159.18 EAX95580.1 - 1.3e-58 198.3 0.0 6.5e-57 192.7 0.0 2.4 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAX95580.1 - 7.2e-26 91.1 11.1 4.5e-16 58.8 4.9 3.1 1 1 1 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 EAX95580.1 - 1.6e-06 28.1 0.1 3.3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain DUF3912 PF13051.6 EAX95580.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) KOW PF00467.29 EAX95580.1 - 5 7.2 6.3 0.52 10.3 0.3 2.6 3 0 0 3 3 3 0 KOW motif BBS2_C PF14782.6 EAX95581.1 - 2.6e-89 300.0 0.0 3.5e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 EAX95581.1 - 9.8e-34 115.7 0.5 2.8e-28 98.1 0.1 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 EAX95581.1 - 2.6e-11 43.4 1.0 9.3e-11 41.6 0.4 2.4 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal PHTB1_N PF14727.6 EAX95581.1 - 0.0033 16.8 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 PTHB1 N-terminus PQQ_2 PF13360.6 EAX95581.1 - 0.011 15.3 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain VCBS PF13517.6 EAX95581.1 - 0.77 10.4 3.1 25 5.6 0.0 3.5 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Plk4_PB2 PF18409.1 EAX95581.1 - 0.85 10.3 3.5 32 5.3 0.0 3.7 3 1 2 5 5 5 0 Polo-like Kinase 4 Polo Box 2 Tim17 PF02466.19 EAX95582.1 - 0.0021 18.4 0.1 0.0035 17.7 0.1 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PUNUT PF16913.5 EAX95582.1 - 0.042 13.1 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Hydrolase_6 PF13344.6 EAX95583.1 - 1.9e-20 72.8 0.2 3.5e-20 72.0 0.1 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EAX95583.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase PF00702.26 EAX95583.1 - 0.003 17.9 0.1 0.011 16.1 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PrpR_N PF06506.11 EAX95583.1 - 0.0087 15.6 0.3 0.017 14.7 0.2 1.5 1 1 0 1 1 1 1 Propionate catabolism activator NAD_binding_10 PF13460.6 EAX95583.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding RibD_C PF01872.17 EAX95583.1 - 0.062 13.1 0.1 0.091 12.6 0.1 1.2 1 0 0 1 1 1 0 RibD C-terminal domain Ank_2 PF12796.7 EAX95584.1 - 4.6e-45 152.1 1.9 1.1e-18 67.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95584.1 - 5.3e-33 112.0 0.0 4.6e-06 26.8 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EAX95584.1 - 9.2e-29 99.1 0.0 4.4e-08 33.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95584.1 - 1.9e-26 92.1 0.0 2.8e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95584.1 - 6.7e-25 84.4 0.0 0.00053 20.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat MCU PF04678.13 EAX95584.1 - 0.016 15.3 0.8 0.031 14.4 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1664 PF07889.12 EAX95584.1 - 0.022 14.8 3.2 0.042 13.9 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EAX95584.1 - 0.059 13.1 4.3 0.15 11.8 4.3 1.7 1 0 0 1 1 1 0 Septum formation initiator DAP_B PF07930.12 EAX95584.1 - 0.14 12.1 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B Clathrin PF00637.20 EAX95584.1 - 0.57 10.1 6.7 15 5.5 6.2 3.1 1 1 1 2 2 2 0 Region in Clathrin and VPS Fib_alpha PF08702.10 EAX95584.1 - 1 9.5 9.5 0.98 9.6 7.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EAX95584.1 - 1.7 9.3 7.1 3.2 8.5 6.6 1.7 1 1 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 EAX95584.1 - 1.9 8.9 7.4 0.28 11.6 3.2 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EAX95584.1 - 2.1 8.8 12.5 4.1 7.9 12.2 1.6 1 1 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 EAX95584.1 - 3 8.4 14.1 0.38 11.3 8.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Gly_rich PF12810.7 EAX95585.1 - 1.9e-23 83.6 28.3 2.3e-23 83.4 28.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX95586.1 - 1.8e-47 162.4 25.2 2.1e-47 162.1 25.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX95587.1 - 5.9e-41 141.0 40.4 7.4e-41 140.7 40.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Cullin_Nedd8 PF10557.9 EAX95588.1 - 2.1e-10 40.4 1.8 9.8e-10 38.3 0.0 2.9 4 0 0 4 4 4 1 Cullin protein neddylation domain Linker_histone PF00538.19 EAX95588.1 - 0.0059 16.9 0.3 1.1 9.7 0.0 4.1 4 1 1 5 5 5 1 linker histone H1 and H5 family PNPase PF03726.14 EAX95588.1 - 0.023 15.2 0.5 0.47 11.0 0.0 2.8 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NleF_casp_inhib PF16809.5 EAX95588.1 - 0.084 12.8 0.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 NleF caspase inhibitor RGS PF00615.19 EAX95588.1 - 0.096 13.0 7.3 0.3 11.4 1.0 3.6 2 1 1 3 3 3 0 Regulator of G protein signaling domain FtsH_ext PF06480.15 EAX95590.1 - 0.054 13.8 0.6 0.11 12.8 0.3 1.7 2 0 0 2 2 2 0 FtsH Extracellular DUF829 PF05705.14 EAX95591.1 - 2.9e-51 174.7 0.7 3.2e-51 174.5 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 EAX95591.1 - 9.2e-05 22.0 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4932 PF16286.5 EAX95591.1 - 0.039 13.2 1.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4932) Peripla_BP_7 PF18610.1 EAX95591.1 - 0.042 14.0 0.3 0.75 10.0 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein domain MS_channel PF00924.18 EAX95591.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel ARA70 PF12489.8 EAX95592.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF4108 PF13390.6 EAX95593.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Defensin_beta PF00711.19 EAX95594.1 - 0.1 12.6 2.8 0.17 11.9 2.8 1.3 1 0 0 1 1 1 0 Beta defensin Metallophos PF00149.28 EAX95595.1 - 4.7e-34 118.7 0.0 6e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX95595.1 - 0.056 13.9 0.1 0.22 12.0 0.1 2.0 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Spc29 PF17082.5 EAX95596.1 - 0.0082 16.0 1.3 0.0082 16.0 1.3 2.3 2 0 0 2 2 2 1 Spindle Pole Component 29 NAD_Gly3P_dh_N PF01210.23 EAX95596.1 - 0.017 15.1 0.1 0.055 13.5 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mt_ATP-synt_B PF05405.14 EAX95596.1 - 0.083 12.5 6.4 0.048 13.3 2.4 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) p450 PF00067.22 EAX95596.1 - 0.26 10.0 3.2 1.8 7.2 1.3 2.3 2 0 0 2 2 2 0 Cytochrome P450 MSA-2c PF12238.8 EAX95596.1 - 1.4 8.9 9.1 0.57 10.2 4.1 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c FAM76 PF16046.5 EAX95596.1 - 1.4 8.2 9.0 0.13 11.6 3.9 1.8 2 0 0 2 2 2 0 FAM76 protein DUF4239 PF14023.6 EAX95596.1 - 4.6 6.9 6.8 3.4 7.4 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) DUF3958 PF13125.6 EAX95596.1 - 6 7.1 15.2 3.4 7.9 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3958) Pkinase PF00069.25 EAX95597.1 - 1.1e-45 156.1 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95597.1 - 2.8e-25 89.1 0.0 3.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95597.1 - 1.2e-08 34.7 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX95597.1 - 0.0003 20.2 0.0 0.00058 19.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX95597.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 EAX95597.1 - 0.045 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CbtA_toxin PF06755.12 EAX95597.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system DUF1489 PF07370.11 EAX95597.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Ras PF00071.22 EAX95598.1 - 8.7e-39 132.7 0.5 1e-38 132.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95598.1 - 8.3e-27 93.8 0.2 1.3e-26 93.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95598.1 - 5.8e-16 58.4 0.1 7.3e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX95598.1 - 7.4e-09 35.7 0.2 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX95598.1 - 2.2e-07 30.6 0.1 9.3e-07 28.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX95598.1 - 9.3e-07 28.4 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX95598.1 - 1.8e-06 28.0 0.1 3.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX95598.1 - 8.6e-05 22.0 0.1 0.00012 21.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAX95598.1 - 0.0035 16.9 0.1 0.0088 15.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EAX95598.1 - 0.01 15.5 0.3 0.077 12.7 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EAX95598.1 - 0.012 14.8 0.4 2.1 7.4 0.0 2.8 1 1 2 3 3 3 0 G-protein alpha subunit MnmE_helical PF12631.7 EAX95598.1 - 0.082 13.1 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 MnmE helical domain GH43_C PF16369.5 EAX95598.1 - 0.52 10.9 3.0 1.1 9.9 0.4 2.1 1 1 1 2 2 2 0 C-terminal lipocalin-like domain Methyltransf_21 PF05050.12 EAX95599.1 - 8.6e-07 29.1 0.1 1.4e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.7 EAX95599.1 - 0.007 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX95599.1 - 0.014 16.1 0.0 0.057 14.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EAX95599.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EAX95599.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EAX95599.1 - 0.16 12.7 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Guanylate_cyc PF00211.20 EAX95600.1 - 1.1e-42 145.7 0.8 1.7e-42 145.1 0.1 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX95600.1 - 3e-07 30.6 1.6 8.6e-07 29.2 1.6 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX95600.1 - 0.00023 21.1 0.1 0.00047 20.1 0.1 1.5 1 0 0 1 1 1 1 PAS fold Sigma_reg_N PF13800.6 EAX95600.1 - 0.48 10.7 13.0 3.1 8.2 4.2 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SK_channel PF03530.14 EAX95600.1 - 0.97 9.4 6.1 1.4 8.9 1.6 2.6 2 0 0 2 2 2 0 Calcium-activated SK potassium channel DUF3377 PF11857.8 EAX95600.1 - 5.6 7.0 6.6 13 5.8 3.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MFS_1 PF07690.16 EAX95601.1 - 0.062 12.2 8.8 0.082 11.8 8.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Snf7 PF03357.21 EAX95604.1 - 1.8e-22 79.7 27.2 2.3e-22 79.4 27.2 1.1 1 0 0 1 1 1 1 Snf7 Hemerythrin PF01814.23 EAX95604.1 - 0.039 14.6 2.2 0.12 13.0 0.4 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Not3 PF04065.15 EAX95604.1 - 0.045 13.2 19.5 0.18 11.2 12.5 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Exonuc_VII_L PF02601.15 EAX95604.1 - 0.056 13.0 9.5 0.063 12.8 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 EAX95604.1 - 1.2 9.5 19.5 3.3 8.1 0.4 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EAX95604.1 - 1.9 8.8 10.7 0.73 10.1 2.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 EAX95604.1 - 2.8 7.2 21.7 2.6 7.3 10.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 EAX95604.1 - 3.2 7.6 25.3 0.34 10.7 3.6 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 EAX95604.1 - 6.4 7.3 9.5 47 4.5 3.8 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HlyD_2 PF12700.7 EAX95604.1 - 7.6 5.2 15.7 17 4.0 0.1 2.0 1 1 1 2 2 2 0 HlyD family secretion protein DUF4829 PF16111.5 EAX95604.1 - 7.8 7.3 12.3 2.6 8.9 6.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) YlqD PF11068.8 EAX95604.1 - 9.6 6.6 22.2 3.4 8.0 14.2 2.6 1 1 2 3 3 3 0 YlqD protein EF-hand_7 PF13499.6 EAX95605.1 - 1.2e-12 48.0 5.9 8.3e-06 26.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAX95605.1 - 1.9e-12 46.8 4.8 2.7e-10 39.9 0.6 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX95605.1 - 4.2e-10 38.7 11.2 0.033 14.1 0.1 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EAX95605.1 - 1.5e-06 27.3 14.3 0.025 14.1 0.1 4.2 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EAX95605.1 - 2.4 7.8 14.5 1.7 8.3 0.3 3.9 4 0 0 4 4 4 0 EF hand Gly-zipper_Omp PF13488.6 EAX95606.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX95606.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF4795 PF16043.5 EAX95607.1 - 0.0049 16.5 7.5 0.45 10.1 1.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAX95607.1 - 0.57 10.5 2.9 3.4 8.0 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Phage_fiber PF03335.13 EAX95607.1 - 3.8 8.0 9.8 0.63 10.3 1.9 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat LRR_5 PF13306.6 EAX95608.1 - 4e-28 97.9 17.9 3.5e-18 65.8 8.7 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95608.1 - 6e-05 22.7 5.6 0.072 12.9 0.9 4.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 EAX95609.1 - 9.8e-166 542.8 179.6 3.4e-22 78.8 14.4 8.7 1 1 9 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95609.1 - 9.5e-26 89.3 24.4 2.2e-05 24.1 0.0 14.6 6 6 12 18 18 18 12 Leucine rich repeat LRR_4 PF12799.7 EAX95609.1 - 2.1e-08 34.3 35.5 0.24 11.9 0.3 11.6 9 3 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX95610.1 - 2.8e-14 53.2 8.5 3.9e-14 52.7 8.5 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Mid2 PF04478.12 EAX95610.1 - 0.0018 18.1 2.0 0.0031 17.4 2.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor PIRT PF15099.6 EAX95610.1 - 0.025 14.2 0.5 0.037 13.6 0.5 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Protocadherin PF08374.11 EAX95610.1 - 0.039 13.9 1.4 0.057 13.4 1.4 1.2 1 0 0 1 1 1 0 Protocadherin LRR_4 PF12799.7 EAX95610.1 - 0.052 14.0 1.5 11 6.5 0.2 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ETRAMP PF09716.10 EAX95610.1 - 0.08 13.0 5.1 0.15 12.1 5.1 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.6 EAX95610.1 - 0.18 11.7 3.8 0.3 11.0 3.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family FdhE PF04216.12 EAX95612.1 - 0.072 13.0 0.5 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation ADD_ATRX PF17981.1 EAX95612.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Cysteine Rich ADD domain DUF4132 PF13569.6 EAX95613.1 - 0.048 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Ribosomal_S15 PF00312.22 EAX95613.1 - 0.48 10.7 2.6 0.62 10.3 0.1 2.4 2 1 0 2 2 2 0 Ribosomal protein S15 Syntaxin_2 PF14523.6 EAX95613.1 - 1.1 9.7 9.5 3.8 8.0 0.1 3.4 3 1 0 3 3 3 0 Syntaxin-like protein Ank_2 PF12796.7 EAX95618.1 - 1.4e-50 169.8 23.8 3.5e-19 69.2 0.8 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95618.1 - 8.1e-44 147.5 9.3 1.6e-08 34.9 0.0 9.2 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX95618.1 - 1.1e-39 133.2 9.9 1.6e-05 25.1 0.1 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 EAX95618.1 - 1.9e-39 129.2 17.7 0.00016 21.8 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EAX95618.1 - 3.8e-30 103.6 20.6 1.7e-08 34.6 0.2 8.4 5 1 6 11 11 11 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX95618.1 - 1.3e-29 101.9 3.8 1.3e-29 101.9 3.8 6.2 3 2 2 5 5 5 3 Domain of unknown function (DUF3447) DUF4455 PF14643.6 EAX95618.1 - 0.056 12.1 2.3 0.034 12.8 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) DUF1759 PF03564.15 EAX95618.1 - 3 7.8 7.4 3.7 7.5 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) LRR_5 PF13306.6 EAX95619.1 - 1.5e-129 425.8 78.8 8.8e-31 106.5 2.7 6.2 2 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95619.1 - 7e-24 83.4 4.0 0.0024 17.6 0.0 9.5 5 2 10 15 15 15 11 Leucine rich repeat LRR_4 PF12799.7 EAX95619.1 - 1.6e-07 31.5 16.3 4.7 7.8 0.4 8.3 4 3 4 8 8 8 5 Leucine Rich repeats (2 copies) Crystall_2 PF09076.10 EAX95619.1 - 0.073 13.0 4.8 6.2 6.8 0.0 3.7 3 1 0 3 3 3 0 Beta/Gamma crystallin DAN PF03045.15 EAX95619.1 - 1.6 8.8 7.7 8.9 6.4 0.1 3.0 3 0 0 3 3 3 0 DAN domain YABBY PF04690.13 EAX95619.1 - 2.6 8.6 5.8 1.3 9.5 0.9 2.7 3 0 0 3 3 3 0 YABBY protein Ank_2 PF12796.7 EAX95620.1 - 1.8e-16 60.5 2.1 9.4e-13 48.6 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95620.1 - 5.5e-13 49.1 0.4 7.7e-05 23.2 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95620.1 - 2.6e-08 34.0 0.1 0.0019 18.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95620.1 - 1.4e-06 28.2 0.1 15 6.5 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat BACK PF07707.15 EAX95620.1 - 0.014 15.5 0.7 0.065 13.3 0.3 2.5 1 1 1 2 2 2 0 BTB And C-terminal Kelch Ank PF00023.30 EAX95620.1 - 0.027 14.9 0.1 10 6.8 0.0 4.0 5 0 0 5 5 5 0 Ankyrin repeat RL PF17797.1 EAX95620.1 - 0.032 14.2 2.4 7.8 6.5 0.0 3.8 3 1 0 3 3 3 0 RL domain Glyco_hydro_31 PF01055.26 EAX95621.1 - 1.9e-114 383.2 0.8 2.6e-114 382.8 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAX95621.1 - 3.1e-19 69.1 1.5 9.1e-19 67.6 0.3 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EAX95621.1 - 2e-07 31.2 0.3 5.4e-07 29.8 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) RhoGAP PF00620.27 EAX95622.1 - 4.7e-25 88.2 0.0 8.5e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EAX95622.1 - 7.9e-10 39.2 0.0 2.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 EAX95622.1 - 0.0083 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 WW domain Homez PF11569.8 EAX95622.1 - 0.02 14.4 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 2-Hacid_dh_C PF02826.19 EAX95623.1 - 5.6e-55 185.4 0.0 9.5e-55 184.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAX95623.1 - 2.5e-25 88.7 0.0 3.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EAX95623.1 - 0.00077 19.6 1.2 0.024 14.7 0.1 2.6 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EAX95623.1 - 0.007 16.9 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain F420_oxidored PF03807.17 EAX95623.1 - 0.013 16.0 3.0 2.6 8.7 1.5 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EAX95623.1 - 0.055 12.8 1.8 0.87 8.8 0.1 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EAX95623.1 - 0.17 12.0 0.6 27 4.8 0.3 2.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EAX95623.1 - 1.9 8.7 4.0 9.6 6.4 1.5 2.7 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ras PF00071.22 EAX95624.1 - 1.2e-39 135.5 0.0 1.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95624.1 - 4.8e-29 101.0 0.1 6.7e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95624.1 - 1.5e-12 47.3 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX95624.1 - 5.9e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX95624.1 - 0.00016 21.1 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX95624.1 - 0.00059 19.8 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX95624.1 - 0.00061 19.4 0.1 0.0031 17.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX95624.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX95624.1 - 0.0034 17.8 0.0 0.0057 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX95624.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ShK PF01549.24 EAX95624.1 - 0.053 14.1 0.4 0.13 12.8 0.1 1.9 2 0 0 2 2 1 0 ShK domain-like AAA_7 PF12775.7 EAX95624.1 - 0.077 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EAX95624.1 - 0.21 11.7 0.1 0.35 11.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX95624.1 - 0.22 11.9 0.5 0.28 11.5 0.5 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX95624.1 - 0.25 11.1 0.3 0.62 9.8 0.4 1.5 1 1 1 2 2 2 0 AAA domain Ebp2 PF05890.12 EAX95625.1 - 2.6e-05 23.9 0.3 3.2e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF5532 PF17673.1 EAX95625.1 - 0.026 14.6 0.2 0.046 13.8 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) Ax_dynein_light PF10211.9 EAX95626.1 - 5.9e-09 36.1 11.1 8.5e-08 32.4 2.5 3.8 3 1 0 3 3 3 2 Axonemal dynein light chain Ppx-GppA PF02541.16 EAX95626.1 - 0.038 13.4 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family WHAMM-JMY_N PF15920.5 EAX95626.1 - 0.077 12.9 0.5 0.44 10.4 0.1 2.3 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated WXG100 PF06013.12 EAX95626.1 - 0.73 10.1 5.6 8.3 6.7 0.2 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG NAPRTase_N PF17767.1 EAX95626.1 - 0.84 10.0 4.9 1.3 9.4 0.1 3.3 5 0 0 5 5 5 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain MutS_III PF05192.18 EAX95626.1 - 1.6 9.0 6.0 0.23 11.7 1.1 2.1 2 1 0 2 2 2 0 MutS domain III AAA_23 PF13476.6 EAX95626.1 - 3.4 8.1 16.8 1 9.8 6.6 2.4 2 0 0 2 2 2 0 AAA domain CENP-H PF05837.12 EAX95626.1 - 4.1 7.9 13.4 2 8.8 0.4 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Pkinase PF00069.25 EAX95627.1 - 8.5e-72 241.7 0.0 1.1e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95627.1 - 1.7e-33 116.0 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX95627.1 - 1e-16 61.3 0.0 1.8e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EAX95627.1 - 4.9e-07 29.8 0.0 9.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 EAX95627.1 - 2.4e-06 28.1 1.3 5.1e-06 27.1 1.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EAX95627.1 - 1.1e-05 25.0 0.0 4.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.6 EAX95627.1 - 0.0001 22.7 1.8 0.026 14.9 1.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EAX95627.1 - 0.0024 18.1 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EAX95627.1 - 0.0087 16.4 0.1 0.046 14.1 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EAX95628.1 - 2.8e-07 31.0 2.2 3.9e-07 30.6 0.6 2.2 2 0 0 2 2 2 1 PH domain TPR_12 PF13424.6 EAX95628.1 - 0.002 18.4 0.1 0.78 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Reg_prop PF07494.11 EAX95628.1 - 0.17 12.2 0.1 0.61 10.5 0.1 1.9 1 0 0 1 1 1 0 Two component regulator propeller DUF3597 PF12200.8 EAX95628.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) OapA PF04225.12 EAX95629.1 - 0.0091 16.1 0.2 0.034 14.3 0.2 2.0 1 0 0 1 1 1 1 Opacity-associated protein A LysM-like domain DUF5631 PF18645.1 EAX95629.1 - 0.046 14.1 0.5 51 4.3 0.0 3.6 3 1 0 3 3 3 0 Family of unknown function (DUF5631) SlyX PF04102.12 EAX95629.1 - 0.053 14.1 1.3 0.053 14.1 1.3 5.5 4 2 3 7 7 7 0 SlyX Myosin_tail_1 PF01576.19 EAX95629.1 - 0.084 10.7 49.3 0.36 8.6 24.2 2.3 1 1 1 2 2 2 0 Myosin tail Phage_lysis PF03245.13 EAX95629.1 - 5.3 7.2 29.8 1.2 9.2 1.7 4.9 2 2 3 5 5 5 0 Bacteriophage Rz lysis protein SLC35F PF06027.12 EAX95630.1 - 2e-38 132.6 31.2 3e-38 132.0 31.2 1.3 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX95630.1 - 7.4e-11 42.4 44.2 3e-06 27.5 18.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAX95630.1 - 0.00083 18.7 30.5 0.0012 18.1 30.5 1.2 1 0 0 1 1 1 1 UAA transporter family Abhydrolase_3 PF07859.13 EAX95631.1 - 1.6e-31 109.8 0.0 1.9e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAX95631.1 - 6.2e-18 64.8 0.5 7.7e-18 64.5 0.5 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase LRR_4 PF12799.7 EAX95632.1 - 4e-16 58.8 14.7 1.3e-06 28.6 0.3 4.3 3 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX95632.1 - 2.7e-12 46.6 2.7 5.5e-08 32.5 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAX95632.1 - 5.4e-10 38.9 9.2 1.6e-05 24.5 0.5 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EAX95632.1 - 0.38 10.9 12.9 5.2 7.4 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_2 PF07723.13 EAX95632.1 - 0.46 11.2 2.2 6.1 7.7 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 EAX95632.1 - 3.2 8.6 8.4 65 4.7 0.1 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat RhoGAP PF00620.27 EAX95633.1 - 2.3e-25 89.2 0.3 3.8e-25 88.5 0.2 1.4 2 0 0 2 2 2 1 RhoGAP domain Chlam_PMP PF02415.17 EAX95634.1 - 1.5e-06 28.3 33.5 0.012 16.1 0.7 7.8 7 0 0 7 7 7 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Syndecan PF01034.20 EAX95634.1 - 7.5e-06 25.8 0.3 1.6e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 Syndecan domain DUF5305 PF17231.2 EAX95634.1 - 0.0017 17.8 0.4 0.0035 16.8 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 EAX95634.1 - 0.013 15.2 0.6 0.03 14.1 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UBX PF00789.20 EAX95635.1 - 0.0059 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 EAX95636.1 - 1.6e-53 181.8 0.0 1.9e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95636.1 - 4.7e-15 55.6 0.0 6.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95636.1 - 0.0018 17.6 0.1 0.0033 16.8 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAX95636.1 - 0.058 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX95636.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAX95636.1 - 0.093 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX95636.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.30 EAX95638.1 - 4.1e-108 349.5 27.1 1.5e-08 34.7 0.0 14.1 14 0 0 14 14 14 14 Ankyrin repeat Ank_2 PF12796.7 EAX95638.1 - 4e-98 322.2 51.3 3.2e-16 59.7 1.7 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95638.1 - 2.5e-95 311.7 22.3 6.2e-12 45.8 0.2 14.2 1 1 14 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95638.1 - 1.2e-80 255.8 25.2 7.8e-06 25.9 0.0 14.1 14 0 0 14 14 14 14 Ankyrin repeat Ank_5 PF13857.6 EAX95638.1 - 4.3e-73 240.4 16.2 6.3e-11 42.3 0.0 8.3 3 3 2 8 8 8 8 Ankyrin repeats (many copies) RL PF17797.1 EAX95638.1 - 6.3e-09 35.7 11.8 1.2 9.1 0.1 8.3 5 3 4 9 9 9 4 RL domain RNase_PH_C PF03725.15 EAX95638.1 - 3.8e-06 26.8 6.3 32 4.7 0.0 8.3 2 1 3 8 8 7 0 3' exoribonuclease family, domain 2 MCC-bdg_PDZ PF10506.9 EAX95638.1 - 3e-05 23.9 20.2 3.5 7.7 0.1 9.7 11 0 0 11 11 11 1 PDZ domain of MCC-2 bdg protein for Usher syndrome MetallophosN PF16371.5 EAX95638.1 - 0.00021 21.5 0.7 8.2 6.8 0.0 5.9 1 1 4 8 8 8 1 N terminal of Calcineurin-like phosphoesterase KdgM PF06178.13 EAX95638.1 - 0.002 17.8 1.2 5.8 6.5 0.0 3.6 3 1 0 3 3 3 2 Oligogalacturonate-specific porin protein (KdgM) DUF1858 PF08984.11 EAX95638.1 - 0.0048 17.0 0.0 40 4.5 0.0 5.3 5 2 2 7 7 6 0 Domain of unknown function (DUF1858) DUF2113 PF09886.9 EAX95638.1 - 0.007 15.7 9.7 0.26 10.6 0.5 4.1 1 1 1 5 5 5 2 Uncharacterized protein conserved in archaea (DUF2113) DUF503 PF04456.12 EAX95638.1 - 0.011 15.5 2.3 21 5.0 0.0 4.7 3 3 3 6 6 6 0 Protein of unknown function (DUF503) BRCT PF00533.26 EAX95638.1 - 0.35 11.3 15.4 76 3.8 1.5 7.0 1 1 3 5 5 5 0 BRCA1 C Terminus (BRCT) domain FeS PF04060.13 EAX95638.1 - 0.42 10.3 9.0 67 3.3 0.0 6.2 8 0 0 8 8 8 0 Putative Fe-S cluster BsuBI_PstI_RE_N PF17728.1 EAX95638.1 - 0.58 10.0 8.6 15 5.5 0.3 3.3 3 0 0 3 3 3 0 BsuBI/PstI restriction endonuclease HTH domain Toxin_8 PF07365.12 EAX95638.1 - 1 9.6 3.7 93 3.3 0.1 3.7 3 0 0 3 3 3 0 Alpha conotoxin precursor DUF2149 PF09919.9 EAX95638.1 - 1.2 9.4 10.8 1.1e+02 3.2 0.4 6.5 3 2 6 10 10 10 0 Uncharacterized conserved protein (DUF2149) eRF1_1 PF03463.15 EAX95638.1 - 1.3 9.0 13.1 14 5.7 0.5 4.8 1 1 1 4 4 4 0 eRF1 domain 1 Skp1 PF01466.19 EAX95639.1 - 0.1 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Gcd10p PF04189.13 EAX95640.1 - 0.016 14.3 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Gcd10p family Carot_N PF09150.10 EAX95640.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal NIF PF03031.18 EAX95641.1 - 4.3e-42 143.5 0.0 5.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ADK_lid PF05191.14 EAX95641.1 - 0.13 12.3 0.5 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid Thioredoxin PF00085.20 EAX95642.1 - 1.5e-15 57.0 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 EAX95642.1 - 5.5e-05 23.5 0.1 8.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 EAX95642.1 - 0.00018 21.3 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAX95642.1 - 0.00097 18.6 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EAX95642.1 - 0.0026 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 EAX95642.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 EAX95642.1 - 0.042 14.3 0.0 0.29 11.6 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAX95642.1 - 0.064 13.6 0.2 0.78 10.1 0.2 2.1 1 1 0 1 1 1 0 Thioredoxin-like NAD_binding_5 PF07994.12 EAX95643.1 - 1.2e-138 461.9 0.0 1.4e-138 461.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EAX95643.1 - 6.7e-30 103.6 0.0 1.6e-29 102.3 0.0 1.7 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase FUR PF01475.19 EAX95643.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Ferric uptake regulator family DUF4625 PF15418.6 EAX95644.1 - 0.0057 16.9 0.1 0.028 14.7 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4625) MG2 PF01835.19 EAX95644.1 - 0.012 16.0 0.1 0.31 11.5 0.0 2.9 2 0 0 2 2 2 0 MG2 domain DUF3324 PF11797.8 EAX95644.1 - 0.019 14.9 4.8 2 8.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function C-terminal (DUF3324) DUF3377 PF11857.8 EAX95644.1 - 0.024 14.5 0.0 0.1 12.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SpaA PF17802.1 EAX95644.1 - 0.03 14.6 0.6 0.03 14.6 0.6 2.6 2 1 0 2 2 2 0 Prealbumin-like fold domain Orf78 PF06024.12 EAX95644.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) TMEM132D_C PF15706.5 EAX95644.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4209 PF13910.6 EAX95645.1 - 0.041 14.1 0.1 1.7 9.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) Vps39_2 PF10367.9 EAX95645.1 - 0.14 12.7 0.6 0.67 10.4 0.6 2.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 EAX95645.1 - 2.4 8.5 9.5 8 6.9 9.5 2.0 1 0 0 1 1 1 0 Ring finger domain PIG-S PF10510.9 EAX95645.1 - 2.7 6.7 6.9 0.27 10.0 2.3 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein zf-RING_11 PF17123.5 EAX95645.1 - 5.8 6.8 12.6 1.3 8.8 7.1 2.7 2 1 0 2 2 2 0 RING-like zinc finger Fibrillin_U_N PF18193.1 EAX95645.1 - 6.1 7.0 6.5 15 5.8 6.5 1.6 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain RRM_1 PF00076.22 EAX95646.1 - 2.2e-20 72.2 1.6 9.5e-14 51.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_28 PF03033.20 EAX95646.1 - 0.026 14.5 0.8 0.1 12.6 0.8 1.9 1 1 1 2 2 2 0 Glycosyltransferase family 28 N-terminal domain APG6 PF04111.12 EAX95648.1 - 2e-11 44.2 0.5 9.7e-11 41.9 0.0 2.2 2 1 0 2 2 2 1 Apg6 BARA domain SUKH_5 PF14567.6 EAX95648.1 - 0.034 13.9 0.2 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall RRM_1 PF00076.22 EAX95649.1 - 2e-06 27.5 0.0 4.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EAX95649.1 - 5.9e-05 23.0 5.0 0.037 14.1 0.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EAX95649.1 - 8e-05 23.3 1.6 0.075 13.7 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 EAX95649.1 - 0.00019 21.2 3.7 0.0018 18.2 0.2 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Haemadin PF09065.10 EAX95649.1 - 0.68 9.8 2.8 33 4.4 2.0 2.5 2 0 0 2 2 2 0 Haemadin zf-C3HC4_3 PF13920.6 EAX95650.1 - 1.7e-07 31.0 7.1 1.7e-07 31.0 7.1 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 EAX95650.1 - 0.011 16.5 1.1 0.011 16.5 1.1 7.9 7 4 2 9 9 9 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX95650.1 - 0.038 14.5 0.9 0.038 14.5 0.9 6.7 7 0 0 7 7 7 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EAX95650.1 - 0.055 14.1 15.2 4.5 8.0 0.7 4.2 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF4193 PF13834.6 EAX95650.1 - 3.6 8.1 9.2 1.2 9.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4193) Histone PF00125.24 EAX95651.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX95651.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX95651.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAX95652.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX95652.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX95652.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX95652.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain TPH PF13868.6 EAX95653.1 - 4.6e-11 41.8 148.9 4.6e-11 41.8 148.9 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain PAS_8 PF13188.7 EAX95654.1 - 0.00052 20.0 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain DDDD PF10161.9 EAX95654.1 - 0.0087 15.8 0.3 8.2 6.3 0.0 3.8 3 0 0 3 3 3 2 Putative mitochondrial precursor protein PAS_9 PF13426.7 EAX95654.1 - 0.021 15.0 0.1 0.091 13.0 0.0 2.1 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 EAX95654.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold GPS2_interact PF15784.5 EAX95655.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX95655.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX95656.1 - 0.023 14.6 8.8 0.038 14.0 8.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF5446 PF17522.2 EAX95657.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) PapD_N PF00345.20 EAX95658.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX95658.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX95659.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX95659.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX95660.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX95660.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Trypan_PARP PF05887.11 EAX95661.1 - 0.025 14.6 7.6 0.038 14.0 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DSPn PF14671.6 EAX95664.1 - 2.7e-36 125.1 0.1 6.3e-36 123.9 0.1 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EAX95664.1 - 4.5e-08 33.0 0.0 1.6e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EAX95664.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EAX95664.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Seryl_tRNA_N PF02403.22 EAX95665.1 - 0.012 15.9 3.3 0.012 15.9 3.3 5.0 3 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF1515 PF07439.11 EAX95665.1 - 0.083 12.9 13.3 0.91 9.6 0.5 4.6 4 2 0 5 5 5 0 Protein of unknown function (DUF1515) Occludin_ELL PF07303.13 EAX95665.1 - 0.47 11.2 23.7 0.075 13.8 2.5 5.0 3 2 2 5 5 5 0 Occludin homology domain DUF16 PF01519.16 EAX95665.1 - 1.2 9.7 43.1 5.9 7.4 6.0 5.6 3 2 2 5 5 5 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EAX95665.1 - 1.4 9.0 39.2 0.021 14.9 4.8 5.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 EAX95665.1 - 5 6.7 44.7 0.25 10.9 3.5 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4795) Cor1 PF04803.12 EAX95665.1 - 6 7.1 33.5 0.17 12.1 1.0 4.8 4 1 1 5 5 5 0 Cor1/Xlr/Xmr conserved region DUF3465 PF11948.8 EAX95666.1 - 0.18 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) DUF326 PF03860.16 EAX95666.1 - 0.66 10.0 2.5 2 8.5 2.5 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) DUF5082 PF16888.5 EAX95667.1 - 4.1e-05 23.9 0.4 0.051 13.9 0.0 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 EAX95667.1 - 0.0001 22.7 0.1 0.00041 20.7 0.1 1.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EAX95667.1 - 0.002 17.1 0.1 0.002 17.1 0.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EAX95667.1 - 0.0043 17.1 0.3 0.005 16.9 0.3 1.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EAX95667.1 - 0.0054 16.1 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EAX95667.1 - 0.0078 16.2 0.1 0.015 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF3829 PF12889.7 EAX95667.1 - 0.0097 15.4 0.9 0.011 15.2 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Phage_GP20 PF06810.11 EAX95667.1 - 0.013 15.3 0.8 0.013 15.3 0.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 HAUS5 PF14817.6 EAX95667.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Snapin_Pallidin PF14712.6 EAX95667.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Snapin/Pallidin LPP PF04728.13 EAX95667.1 - 0.023 15.0 0.4 0.24 11.8 0.4 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper HsbA PF12296.8 EAX95667.1 - 0.031 14.7 0.3 0.11 13.0 0.3 1.8 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF4618 PF15397.6 EAX95667.1 - 0.031 13.7 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 EAX95667.1 - 0.031 14.3 0.1 0.039 14.0 0.1 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 EAX95667.1 - 0.033 14.0 0.3 0.033 14.0 0.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) WXG100 PF06013.12 EAX95667.1 - 0.041 14.1 0.1 0.089 13.0 0.1 1.5 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 EAX95667.1 - 0.068 13.4 0.2 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 EAX95667.1 - 0.073 12.9 0.1 0.078 12.8 0.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4795 PF16043.5 EAX95667.1 - 0.085 12.4 0.2 0.11 12.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DASH_Dam1 PF08653.10 EAX95667.1 - 0.09 12.6 0.3 4.7 7.1 0.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 RACo_C_ter PF14574.6 EAX95667.1 - 0.093 11.8 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain DASH_Duo1 PF08651.10 EAX95667.1 - 0.1 12.3 0.3 4.2 7.2 0.0 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 STAT_alpha PF01017.20 EAX95667.1 - 0.11 12.4 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 STAT protein, all-alpha domain Fusion_gly PF00523.18 EAX95667.1 - 0.13 10.4 0.2 0.15 10.2 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Pet191_N PF10203.9 EAX95668.1 - 6.1 7.2 8.6 13 6.1 0.7 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Ank_2 PF12796.7 EAX95669.1 - 0.0002 21.9 0.0 0.00058 20.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95669.1 - 0.00034 20.8 0.0 0.0021 18.4 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX95669.1 - 0.0015 19.1 0.0 0.039 14.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95669.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Phi-29_GP3 PF05435.11 EAX95669.1 - 0.017 14.6 0.7 0.04 13.4 0.6 1.6 1 1 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Ank PF00023.30 EAX95669.1 - 0.024 15.1 0.0 0.086 13.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat FlaF PF07309.11 EAX95669.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF Ank_2 PF12796.7 EAX95670.1 - 2.8e-10 40.6 0.4 0.00085 19.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95670.1 - 2.4e-07 30.9 0.0 0.0004 20.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95670.1 - 3.9e-05 24.1 0.0 0.011 16.3 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95670.1 - 6.1e-05 23.1 0.0 3.5 8.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX95671.1 - 5.3e-26 91.0 3.9 2.6e-05 24.7 0.0 7.8 3 2 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95671.1 - 2e-21 76.0 2.4 0.0009 19.8 0.0 8.3 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95671.1 - 5.1e-11 41.8 2.6 0.54 11.0 0.0 10.7 12 0 0 12 12 12 1 Ankyrin repeat Ank_5 PF13857.6 EAX95671.1 - 1.1e-08 35.2 0.1 0.08 13.3 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX95671.1 - 1.3e-07 31.7 0.6 0.076 13.5 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat DUF496 PF04363.12 EAX95671.1 - 0.0047 16.9 11.7 0.027 14.5 0.3 4.6 3 1 1 4 4 4 1 Protein of unknown function (DUF496) HTH_34 PF13601.6 EAX95671.1 - 0.0051 17.0 0.1 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain PTS_2-RNA PF01885.16 EAX95671.1 - 0.12 12.4 0.4 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DED PF01335.21 EAX95671.1 - 4.7 7.6 5.6 3.6 8.0 0.2 3.5 4 1 0 4 4 4 0 Death effector domain PSP PF04046.16 EAX95672.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95673.1 - 0.12 13.0 7.1 6.8 7.8 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX95673.1 - 4 7.4 7.9 4.4 7.3 7.9 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX95675.1 - 1.7e-23 82.4 9.1 1.7e-23 82.4 9.1 3.4 3 1 1 4 4 3 1 Phage tail repeat like DUF4116 PF13475.6 EAX95675.1 - 0.036 13.8 1.0 0.075 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX95676.1 - 6.5e-155 513.6 14.1 8.1e-155 513.3 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX95676.1 - 0.13 12.9 4.5 0.33 11.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX95676.1 - 0.22 11.4 1.4 0.85 9.5 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase Glu-tRNAGln PF02686.15 EAX95676.1 - 0.5 10.7 2.5 0.97 9.8 1.1 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAX95676.1 - 0.57 10.7 5.9 5 7.7 0.5 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX95677.1 - 0.00015 22.3 0.7 0.00038 21.0 0.3 2.0 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX95677.1 - 0.0046 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Baculoviridae ME53 Lectin_legB PF00139.19 EAX95677.1 - 0.0055 16.3 0.3 0.088 12.3 0.1 2.0 2 0 0 2 2 2 1 Legume lectin domain Myb_DNA-bind_6 PF13921.6 EAX95678.1 - 1.1e-24 86.4 0.9 1.6e-14 53.8 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX95678.1 - 1.5e-21 76.3 1.1 1.6e-10 41.0 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EAX95678.1 - 2.7e-05 24.1 0.0 0.17 12.0 0.0 3.7 3 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain FRB_dom PF08771.11 EAX95678.1 - 0.12 12.8 2.6 0.15 12.5 0.2 2.2 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain SANT_DAMP1_like PF16282.5 EAX95678.1 - 1.3 9.3 4.5 0.47 10.7 0.3 2.4 3 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF3395 PF11875.8 EAX95678.1 - 2 8.3 13.3 6.5 6.6 13.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) Folliculin PF11704.8 EAX95680.1 - 5.1e-05 23.2 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Bromo_TP PF07524.13 EAX95680.1 - 0.057 13.4 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated CitX PF03802.14 EAX95680.1 - 0.12 12.2 0.2 0.27 11.0 0.2 1.6 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase FapA PF03961.13 EAX95680.1 - 0.21 10.1 0.5 0.31 9.6 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TBCA PF02970.16 EAX95680.1 - 0.69 10.3 3.9 1.3 9.4 2.4 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A SpoVT_C PF15714.5 EAX95681.1 - 0.055 13.5 0.4 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Stage V sporulation protein T C-terminal, transcription factor FAM184 PF15665.5 EAX95682.1 - 0.98 9.2 46.5 0.17 11.7 6.8 4.6 2 1 2 4 4 4 0 Family with sequence similarity 184, A and B DUF883 PF05957.13 EAX95682.1 - 1.8 9.2 13.4 1.1 9.9 1.0 3.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF885 PF05960.11 EAX95682.1 - 4.8 6.7 11.4 14 5.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Baculo_PEP_C PF04513.12 EAX95682.1 - 5.4 7.1 44.5 0.6 10.1 7.5 4.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EAX95682.1 - 7.2 5.9 33.4 0.68 9.2 3.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 EAX95683.1 - 5.1e-05 23.2 2.2 5.1e-05 23.2 2.2 3.1 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain ZnuA PF01297.17 EAX95683.1 - 0.015 14.8 0.6 0.015 14.8 0.6 5.2 1 1 2 5 5 5 0 Zinc-uptake complex component A periplasmic YojJ PF10372.9 EAX95683.1 - 0.026 14.6 0.8 0.026 14.6 0.8 5.5 3 2 3 7 7 7 0 Bacterial membrane-spanning protein N-terminus Baculo_PEP_C PF04513.12 EAX95683.1 - 0.12 12.4 32.4 0.79 9.8 3.8 4.7 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EAX95683.1 - 0.43 8.0 73.1 0.015 12.9 22.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ApoO PF09769.9 EAX95683.1 - 9.2 6.2 26.2 4.2 7.3 2.2 5.8 2 2 3 5 5 5 0 Apolipoprotein O VPS9 PF02204.18 EAX95685.1 - 0.0027 17.9 1.0 0.0063 16.7 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF563 PF04577.14 EAX95686.1 - 3.3e-41 141.7 1.0 5.3e-41 141.1 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF2811 PF10929.8 EAX95687.1 - 0.023 14.9 0.1 0.051 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) CRM1_C PF08767.11 EAX95687.1 - 0.2 10.8 0.9 1.2 8.2 0.3 1.9 1 1 1 2 2 2 0 CRM1 C terminal zf-B_box PF00643.24 EAX95688.1 - 2.8e-12 46.6 6.6 4.4e-12 46.0 6.6 1.3 1 0 0 1 1 1 1 B-box zinc finger MATH PF00917.26 EAX95688.1 - 4.1e-06 26.9 1.7 6.2e-06 26.3 0.0 2.2 2 1 1 3 3 3 1 MATH domain LysM PF01476.20 EAX95688.1 - 0.071 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 LysM domain DUF1826 PF08856.11 EAX95688.1 - 0.095 12.6 0.2 0.19 11.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1826) DUF2183 PF09949.9 EAX95688.1 - 0.19 12.1 1.7 0.55 10.6 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) LMBR1 PF04791.16 EAX95688.1 - 1.8 7.3 4.5 2.4 6.9 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tnp_zf-ribbon_2 PF13842.6 EAX95688.1 - 3.8 8.4 10.4 8.8 7.2 10.4 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon CENP-Q PF13094.6 EAX95688.1 - 4.6 7.4 12.6 0.36 11.0 6.9 2.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Synaptobrevin PF00957.21 EAX95688.1 - 7.3 6.5 7.6 3.6 7.4 0.4 2.5 2 0 0 2 2 2 0 Synaptobrevin TMPIT PF07851.13 EAX95688.1 - 7.9 5.6 7.6 23 4.1 6.7 2.1 2 1 0 2 2 2 0 TMPIT-like protein CH_2 PF06294.11 EAX95689.1 - 0.00034 20.7 0.0 0.0005 20.1 0.0 1.2 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 EAX95689.1 - 0.033 14.4 0.1 0.068 13.4 0.0 1.6 2 0 0 2 2 2 0 Calponin homology (CH) domain Peptidase_C1 PF00112.23 EAX95690.1 - 0.00081 19.5 2.0 0.26 11.4 0.3 2.5 2 1 0 2 2 2 2 Papain family cysteine protease APG12 PF04110.13 EAX95691.1 - 1.3e-08 35.1 0.1 1.5e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EAX95691.1 - 0.0015 18.7 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF563 PF04577.14 EAX95693.1 - 4.9e-17 62.8 0.1 1.2e-16 61.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Fmp27_GFWDK PF10347.9 EAX95694.1 - 1.9e-31 109.3 1.0 6.3e-31 107.6 0.1 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 EAX95694.1 - 2.9e-18 66.0 1.4 1.6e-09 37.1 0.2 2.4 1 1 0 2 2 2 2 Golgi-body localisation protein domain Ank_2 PF12796.7 EAX95695.1 - 2.1e-12 47.5 4.0 0.042 14.4 0.0 6.8 4 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95695.1 - 1.5e-07 31.5 0.0 0.61 10.5 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95695.1 - 4.2e-07 29.7 1.5 5.1 8.0 0.0 7.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 EAX95695.1 - 2.6e-05 24.7 4.5 3.9 8.2 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX95695.1 - 0.0019 18.5 0.3 0.68 10.5 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 EAX95695.1 - 0.0054 16.7 3.3 0.0054 16.7 3.3 7.0 4 2 4 8 8 8 3 Domain of unknown function (DUF3447) Pox_A32 PF04665.12 EAX95697.1 - 7.8e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX95697.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX95697.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX95697.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1947 PF09183.10 EAX95698.1 - 0.067 13.5 0.2 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Phage_fiber PF03335.13 EAX95698.1 - 9.6 6.7 21.6 2.1 8.7 3.3 3.5 3 0 0 3 3 3 0 Phage tail fibre repeat KilA-N PF04383.13 EAX95699.1 - 9e-19 67.4 0.9 2.5e-18 65.9 0.9 1.8 1 1 0 1 1 1 1 KilA-N domain ELYS-bb PF16687.5 EAX95699.1 - 0.096 11.3 0.4 0.13 10.8 0.3 1.2 1 1 0 1 1 1 0 beta-propeller of ELYS nucleoporin Chal_sti_synt_N PF00195.19 EAX95699.1 - 0.4 10.1 1.2 1.4 8.3 0.6 2.1 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Armet PF10208.9 EAX95699.1 - 1.9 8.4 10.6 0.32 10.9 1.5 2.7 1 1 1 3 3 3 0 Degradation arginine-rich protein for mis-folding DUF3839 PF12943.7 EAX95700.1 - 1.9e-100 335.3 7.9 2.4e-100 335.0 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX95700.1 - 0.12 12.9 2.0 0.84 10.1 0.9 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5398 PF17376.2 EAX95700.1 - 0.2 12.3 2.1 0.41 11.3 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Baculo_PEP_C PF04513.12 EAX95701.1 - 0.00013 22.0 25.2 0.067 13.2 0.5 4.2 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EAX95701.1 - 0.00024 21.1 26.2 0.015 15.2 12.4 2.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EAX95701.1 - 0.028 14.5 20.8 0.047 13.7 1.7 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 EAX95701.1 - 0.037 13.6 24.9 0.18 11.4 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PIN_8 PF18476.1 EAX95701.1 - 0.052 13.4 22.4 0.16 11.8 1.7 3.2 1 1 2 3 3 3 0 PIN like domain YlqD PF11068.8 EAX95701.1 - 0.063 13.6 34.2 0.48 10.8 1.6 4.3 1 1 3 4 4 4 0 YlqD protein Peptidase_M61 PF05299.12 EAX95701.1 - 0.094 13.1 0.2 0.094 13.1 0.2 3.6 2 1 1 3 3 3 0 M61 glycyl aminopeptidase Tox-REase-7 PF15649.6 EAX95701.1 - 0.24 11.7 2.5 0.47 10.8 0.3 2.5 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 7 Fib_alpha PF08702.10 EAX95701.1 - 0.49 10.6 25.4 1.4 9.1 4.3 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 EAX95701.1 - 0.57 10.8 21.7 1.4 9.5 0.5 4.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal DUF2935 PF11155.8 EAX95701.1 - 1.9 8.9 9.4 10 6.5 4.8 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Occludin_ELL PF07303.13 EAX95701.1 - 2.1 9.1 15.0 4.9 7.9 0.7 3.9 2 1 2 4 4 4 0 Occludin homology domain Fzo_mitofusin PF04799.13 EAX95701.1 - 3.8 7.0 25.5 1.1 8.8 1.3 4.4 1 1 3 4 4 4 0 fzo-like conserved region DUF883 PF05957.13 EAX95701.1 - 5.5 7.7 18.0 0.9 10.2 1.0 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) MIEAP PF16026.5 EAX95701.1 - 7.1 6.8 11.6 0.16 12.2 0.9 2.3 1 1 1 2 2 2 0 Mitochondria-eating protein Lant_dehydr_C PF14028.6 EAX95701.1 - 7.9 5.9 10.4 28 4.1 4.0 3.3 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term T3SS_needle_F PF09392.10 EAX95701.1 - 8.6 6.6 18.5 22 5.3 2.0 5.8 3 1 2 6 6 6 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Snf7 PF03357.21 EAX95702.1 - 9.4e-15 54.6 16.1 1.5e-14 53.9 16.1 1.3 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 EAX95702.1 - 0.011 15.3 0.9 0.011 15.3 0.9 1.8 2 0 0 2 2 2 0 PspA/IM30 family PKcGMP_CC PF16808.5 EAX95702.1 - 0.7 9.8 5.0 0.35 10.7 1.7 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase tRNA-synt_1d PF00750.19 EAX95703.1 - 0.0058 15.6 4.0 0.0058 15.6 4.0 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (R) DUF5320 PF17253.2 EAX95703.1 - 0.5 11.5 4.6 8.1 7.6 0.3 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5320) DUF4735 PF15882.5 EAX95703.1 - 2.5 7.5 12.1 0.56 9.6 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) FtsL PF04999.13 EAX95703.1 - 6.1 6.9 11.9 6 6.9 0.1 4.0 3 1 1 4 4 4 0 Cell division protein FtsL Muted PF14942.6 EAX95703.1 - 7.7 6.8 31.6 2.2 8.6 7.9 3.6 2 2 2 4 4 4 0 Organelle biogenesis, Muted-like protein Matrilin_ccoil PF10393.9 EAX95703.1 - 8.5 6.3 9.5 0.38 10.6 0.9 3.2 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin ArfGap PF01412.18 EAX95704.1 - 7e-33 113.2 0.7 1.1e-32 112.5 0.5 1.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf PhdYeFM_antitox PF02604.19 EAX95704.1 - 0.038 13.8 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system zf-piccolo PF05715.13 EAX95704.1 - 0.18 12.0 3.0 0.13 12.4 1.4 1.6 2 0 0 2 2 2 0 Piccolo Zn-finger TPK_catalytic PF04263.16 EAX95706.1 - 4.7e-30 104.1 0.0 7e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EAX95706.1 - 6.9e-14 51.3 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain ARD PF03079.14 EAX95706.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family PDZ_2 PF13180.6 EAX95706.1 - 0.088 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Mur_ligase_C PF02875.21 EAX95706.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain IBD PF10416.9 EAX95708.1 - 4.6e-11 42.8 0.0 5.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Peptidase_C2 PF00648.21 EAX95710.1 - 5.2e-63 212.8 0.2 8.1e-63 212.2 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF505 PF04458.12 EAX95710.1 - 0.006 15.0 0.0 0.006 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF505) RR_TM4-6 PF06459.12 EAX95710.1 - 3.5 7.4 15.8 9 6.0 15.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_5 PF13306.6 EAX95711.1 - 4.2e-136 447.0 112.0 4.2e-29 101.1 6.9 9.0 4 2 5 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95711.1 - 6.5e-23 80.3 3.5 0.0018 18.0 0.0 11.8 8 3 6 14 14 14 6 Leucine rich repeat Vps16_N PF04841.13 EAX95712.1 - 2.2e-15 56.3 0.0 3.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAX95712.1 - 0.0036 16.4 3.7 0.025 13.7 2.1 2.2 2 0 0 2 2 2 1 Vps16, C-terminal region SNARE PF05739.19 EAX95713.1 - 1.7e-05 24.7 0.2 1.7e-05 24.7 0.2 2.7 4 0 0 4 4 4 1 SNARE domain Syntaxin-6_N PF09177.11 EAX95713.1 - 0.00026 21.5 0.1 0.00026 21.5 0.1 2.6 1 1 1 2 2 2 1 Syntaxin 6, N-terminal ODV-E18 PF10717.9 EAX95713.1 - 0.014 15.3 0.9 0.027 14.4 0.9 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 EAX95713.1 - 0.056 12.2 3.4 0.076 11.8 1.7 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1664 PF07889.12 EAX95713.1 - 0.082 12.9 11.1 0.88 9.6 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4806 PF16064.5 EAX95713.1 - 0.18 12.1 5.6 1.1 9.6 0.3 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4806) YscO-like PF16789.5 EAX95713.1 - 1.2 9.1 8.7 1.2 9.2 0.2 2.4 3 0 0 3 3 3 0 YscO-like protein PhaP_Bmeg PF09602.10 EAX95713.1 - 1.4 8.8 11.8 0.065 13.2 2.5 2.4 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF16 PF01519.16 EAX95713.1 - 1.7 9.2 14.0 1.8 9.1 2.7 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 EAX95713.1 - 4.8 7.7 16.3 16 6.0 3.2 4.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4101 PF13355.6 EAX95714.1 - 0.0085 16.5 2.3 0.053 14.0 0.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4101) CtIP_N PF10482.9 EAX95714.1 - 0.019 15.0 5.0 0.019 15.0 5.0 1.9 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain JIP_LZII PF16471.5 EAX95714.1 - 0.027 14.6 8.0 0.038 14.2 0.9 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 EAX95714.1 - 0.093 13.1 0.7 0.093 13.1 0.7 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 EAX95714.1 - 0.24 11.9 19.9 0.048 14.1 6.0 3.1 1 1 1 2 2 2 0 Cell division protein ZapB PCRF PF03462.18 EAX95714.1 - 0.27 11.1 7.7 0.18 11.7 4.1 2.1 1 1 1 2 2 2 0 PCRF domain YabA PF06156.13 EAX95714.1 - 1.3 9.7 15.6 0.2 12.3 2.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA DIMCO_N PF16844.5 EAX95714.1 - 2 8.8 7.0 8.5 6.8 1.2 2.4 1 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Cep57_MT_bd PF06657.13 EAX95714.1 - 2.3 8.8 9.3 0.98 9.9 1.7 3.3 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 XkdW PF09636.10 EAX95714.1 - 2.3 8.3 7.5 0.97 9.6 0.5 2.9 2 1 0 3 3 3 0 XkdW protein Nas2_N PF18265.1 EAX95714.1 - 3.6 7.6 9.7 1.7 8.6 0.3 3.1 3 1 0 3 3 3 0 Nas2 N_terminal domain DivIC PF04977.15 EAX95714.1 - 5.7 6.8 13.1 0.95 9.3 0.8 3.2 1 1 0 2 2 2 0 Septum formation initiator Prefoldin PF02996.17 EAX95714.1 - 6.4 6.7 11.0 17 5.4 0.2 3.2 2 1 1 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.10 EAX95714.1 - 7.7 6.7 11.6 9.2 6.4 0.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ank_4 PF13637.6 EAX95716.1 - 4.2e-41 138.8 5.8 4.3e-12 46.3 0.0 8.8 4 2 6 10 10 10 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95716.1 - 3.9e-33 113.9 3.4 1.2e-12 48.2 0.1 4.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95716.1 - 6.8e-32 105.9 8.8 0.00013 22.1 0.0 9.3 10 1 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX95716.1 - 3.4e-30 103.8 2.1 3.4e-30 103.8 2.1 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX95716.1 - 1.6e-28 97.9 7.2 3.2e-05 24.2 0.0 7.4 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX95716.1 - 3.2e-25 87.9 2.1 6.9e-07 29.4 0.1 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 EAX95717.1 - 4.4e-14 52.9 0.0 7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX95717.1 - 5e-11 43.2 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAX95717.1 - 1.6e-08 34.6 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX95717.1 - 4.3e-08 33.1 0.2 6.8e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX95717.1 - 1.2e-05 25.9 0.0 3.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAX95717.1 - 0.00028 20.3 0.0 0.00051 19.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EAX95717.1 - 0.00041 20.3 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Porin_3 PF01459.22 EAX95719.1 - 1.4e-07 31.3 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic porin Phospholip_B PF04916.13 EAX95720.1 - 1.8e-131 439.4 4.9 2.2e-131 439.1 4.9 1.0 1 0 0 1 1 1 1 Phospholipase B PSI_integrin PF17205.3 EAX95720.1 - 0.46 10.3 2.2 0.9 9.3 2.2 1.4 1 0 0 1 1 1 0 Integrin plexin domain TPR_19 PF14559.6 EAX95721.1 - 1.2e-13 51.3 0.6 5.4e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX95721.1 - 2.9e-11 42.6 6.3 0.0011 19.0 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX95721.1 - 4.1e-11 42.9 7.2 3.5e-06 27.1 0.3 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAX95721.1 - 4.8e-11 42.6 1.5 0.0011 19.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX95721.1 - 3.4e-08 34.0 0.0 0.00048 20.7 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX95721.1 - 5e-08 33.1 0.0 0.0056 17.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX95721.1 - 7.8e-08 32.5 5.4 0.0012 19.1 0.2 3.5 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX95721.1 - 4.1e-07 29.5 2.1 0.041 13.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX95721.1 - 5.9e-06 25.9 1.0 0.12 12.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX95721.1 - 0.00025 21.0 2.7 0.029 14.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAX95721.1 - 0.00033 20.3 1.3 0.0038 16.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat Fis1_TPR_C PF14853.6 EAX95721.1 - 0.0011 19.0 2.2 6.6 6.9 0.0 4.2 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAX95721.1 - 0.0015 18.2 0.0 0.31 10.7 0.0 2.4 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 EAX95721.1 - 0.0022 18.0 3.2 0.11 12.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAX95721.1 - 0.0091 15.8 0.1 4.6 7.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAX95721.1 - 0.0095 16.1 0.6 2 8.6 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX95721.1 - 0.74 10.3 5.3 17 6.1 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 EAX95722.1 - 0.015 15.5 0.9 5 7.4 0.1 2.7 3 0 0 3 3 3 0 PPR repeat family DUF3024 PF11225.8 EAX95722.1 - 0.046 14.0 0.4 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Shikimate_DH PF01488.20 EAX95722.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dynamin_M PF01031.20 EAX95723.1 - 4.6e-73 245.9 0.2 1.3e-72 244.4 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EAX95723.1 - 4.1e-53 179.9 0.1 7.6e-53 179.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAX95723.1 - 1.9e-16 60.0 0.9 6.1e-16 58.4 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAX95723.1 - 1.2e-05 25.4 0.4 0.00014 21.9 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX95723.1 - 0.0049 17.3 0.0 0.022 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EAX95723.1 - 0.026 14.7 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EAX95723.1 - 0.05 13.8 0.0 0.57 10.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EAX95723.1 - 0.056 12.7 0.3 9.3 5.5 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin SRPRB PF09439.10 EAX95723.1 - 0.073 12.5 0.0 5.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Ank_2 PF12796.7 EAX95724.1 - 7.9e-114 372.5 11.5 3.8e-20 72.3 0.1 5.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95724.1 - 1.6e-63 210.3 0.0 3.1e-12 46.8 0.0 6.8 5 2 3 8 8 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX95724.1 - 5.8e-62 203.6 0.0 3.3e-05 24.1 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX95724.1 - 2.3e-59 196.7 0.0 6.2e-08 32.8 0.0 9.2 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95724.1 - 1.1e-47 154.5 0.0 0.00082 19.6 0.0 9.8 10 0 0 10 10 9 8 Ankyrin repeat Ribosomal_L17 PF01196.19 EAX95724.1 - 0.00035 21.4 0.3 15 6.6 0.3 5.5 1 1 1 2 2 2 0 Ribosomal protein L17 DUF4763 PF15960.5 EAX95724.1 - 0.00062 19.2 6.9 0.0011 18.4 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) TMF_DNA_bd PF12329.8 EAX95724.1 - 0.00068 19.6 13.2 0.0024 17.8 13.2 2.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 EAX95724.1 - 0.0054 15.8 7.2 0.0079 15.3 7.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rhamnogal_lyase PF06045.11 EAX95724.1 - 0.017 14.5 0.8 0.28 10.5 0.2 2.4 2 0 0 2 2 2 0 Rhamnogalacturonate lyase family DUF1664 PF07889.12 EAX95724.1 - 0.02 15.0 2.4 0.035 14.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 EAX95724.1 - 0.021 14.7 1.1 0.021 14.7 1.1 2.0 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Vps5 PF09325.10 EAX95724.1 - 0.022 14.3 9.8 0.036 13.6 9.8 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Sec34 PF04136.15 EAX95724.1 - 0.025 14.4 9.5 0.046 13.6 9.5 1.3 1 0 0 1 1 1 0 Sec34-like family Swi5 PF07061.11 EAX95724.1 - 0.038 14.1 7.3 0.097 12.8 7.3 1.7 1 0 0 1 1 1 0 Swi5 ZapB PF06005.12 EAX95724.1 - 0.041 14.3 12.6 0.097 13.1 12.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB E2F_CC-MB PF16421.5 EAX95724.1 - 0.065 13.6 5.2 0.28 11.6 4.3 2.6 3 1 0 3 3 2 0 E2F transcription factor CC-MB domain DUF4164 PF13747.6 EAX95724.1 - 0.078 13.3 2.4 0.14 12.5 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 EAX95724.1 - 0.12 12.4 6.0 0.24 11.4 6.0 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF2968 PF11180.8 EAX95724.1 - 0.13 11.9 6.1 0.25 10.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3450 PF11932.8 EAX95724.1 - 0.14 11.5 7.6 0.2 10.9 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EAX95724.1 - 0.16 12.2 7.4 0.42 10.8 7.4 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HJURP_mid PF12346.8 EAX95724.1 - 0.17 12.4 0.3 0.17 12.4 0.3 1.7 2 0 0 2 2 1 0 Holliday junction recognition protein-associated repeat DDE_Tnp_IS240 PF13610.6 EAX95724.1 - 0.18 12.1 4.1 0.18 12.0 2.7 1.8 2 0 0 2 2 1 0 DDE domain ABC_tran_CTD PF16326.5 EAX95724.1 - 0.18 12.1 4.0 0.4 11.0 4.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 EAX95724.1 - 0.23 11.6 11.5 0.45 10.7 11.5 1.5 1 0 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 EAX95724.1 - 0.23 12.0 8.6 0.46 11.0 8.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 EAX95724.1 - 0.31 11.4 9.4 0.88 10.0 9.4 1.8 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Med4 PF10018.9 EAX95724.1 - 0.57 9.8 6.1 1.1 9.0 6.1 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Lipoprotein_20 PF13942.6 EAX95724.1 - 0.69 9.8 5.7 1.2 9.0 5.7 1.4 1 0 0 1 1 1 0 YfhG lipoprotein DUF3552 PF12072.8 EAX95724.1 - 0.69 9.3 11.5 0.28 10.6 8.4 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 EAX95724.1 - 0.87 8.9 2.8 1.3 8.3 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EAX95724.1 - 1.1 9.0 11.3 0.13 12.0 6.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NPV_P10 PF05531.12 EAX95724.1 - 1.2 9.6 7.2 5.6 7.5 7.2 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EAX95724.1 - 1.6 9.4 9.8 4.5 8.0 9.8 1.9 1 1 0 1 1 1 0 Initiation control protein YabA PCRF PF03462.18 EAX95724.1 - 2.2 8.1 6.9 3.7 7.4 6.9 1.4 1 0 0 1 1 1 0 PCRF domain CCDC-167 PF15188.6 EAX95724.1 - 2.3 8.6 7.4 1.8 8.9 0.7 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin PF02996.17 EAX95724.1 - 3.6 7.5 10.4 1.2 9.0 3.1 2.7 1 1 1 2 2 2 0 Prefoldin subunit TSC22 PF01166.18 EAX95724.1 - 3.8 7.9 6.9 0.38 11.1 1.5 2.1 2 0 0 2 2 1 0 TSC-22/dip/bun family FlaC_arch PF05377.11 EAX95724.1 - 4.1 7.9 8.6 32 5.0 8.4 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EAX95724.1 - 4.2 6.5 8.0 6.6 5.9 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein GTP-bdg_M PF16360.5 EAX95724.1 - 8 7.1 6.0 44 4.8 0.9 2.7 1 1 2 3 3 3 0 GTP-binding GTPase Middle Region TAFII28 PF04719.14 EAX95725.1 - 3.9e-07 30.1 0.2 1.3e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EAX95725.1 - 0.0024 18.1 0.0 0.0073 16.6 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 EAX95725.1 - 0.17 11.9 9.7 0.17 11.8 9.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LSM PF01423.22 EAX95726.1 - 7.1e-13 48.0 0.6 1.1e-12 47.5 0.6 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAX95726.1 - 6.7e-06 26.2 0.1 7.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EAX95726.1 - 0.012 15.2 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein CS PF04969.16 EAX95727.1 - 4.3e-10 40.5 2.2 4.3e-10 40.5 2.2 1.9 2 0 0 2 2 2 1 CS domain ANAPC3 PF12895.7 EAX95727.1 - 1.1e-07 32.0 1.5 1.7e-07 31.3 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 EAX95727.1 - 1.5e-05 24.9 1.2 3.4e-05 23.8 1.2 1.6 1 1 0 1 1 1 1 Putative TPR-like repeat TPR_2 PF07719.17 EAX95727.1 - 0.0033 17.4 4.0 1.8 8.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAX95727.1 - 0.0061 16.3 5.9 0.12 12.2 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX95727.1 - 0.016 15.4 0.4 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gly_rich PF12810.7 EAX95728.1 - 1.6e-19 70.8 31.7 2e-19 70.5 31.7 1.0 1 0 0 1 1 1 1 Glycine rich protein TTL PF03133.15 EAX95729.1 - 2.9e-65 220.3 1.1 2.9e-65 220.3 1.1 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family Pkinase_Tyr PF07714.17 EAX95729.1 - 4.4e-18 65.5 0.0 7.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95729.1 - 4e-13 49.3 0.0 9.6e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ATPgrasp_YheCD PF14398.6 EAX95729.1 - 2.3e-11 43.4 0.2 2.4e-05 23.7 0.0 3.6 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX95729.1 - 4.1e-07 29.5 0.0 0.00078 18.8 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX95729.1 - 0.0013 18.8 0.0 0.017 15.1 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EAX95729.1 - 0.0014 18.2 0.5 3.3 7.3 0.0 3.2 3 0 0 3 3 3 2 RimK-like ATP-grasp domain Exog_C PF18026.1 EAX95729.1 - 0.051 13.6 0.1 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Dala_Dala_lig_C PF07478.13 EAX95729.1 - 0.059 12.9 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 D-ala D-ala ligase C-terminus WD40 PF00400.32 EAX95730.1 - 7.7e-11 42.4 9.3 5.7e-07 30.1 0.4 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95730.1 - 4.2e-06 27.0 0.0 8.6e-05 22.8 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 EAX95730.1 - 2.5e-05 24.5 6.2 5.9e-05 23.3 5.1 2.0 1 1 1 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain DUF3399 PF11879.8 EAX95730.1 - 0.013 15.8 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Nup160 PF11715.8 EAX95730.1 - 0.069 11.8 0.1 0.56 8.8 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 EAX95730.1 - 0.15 12.0 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 EAX95731.1 - 8.4e-42 143.3 0.0 9.9e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95731.1 - 4.6e-18 65.4 0.0 1.5e-17 63.7 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX95731.1 - 0.00036 20.5 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX95731.1 - 0.063 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EAX95731.1 - 0.21 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family TPH PF13868.6 EAX95732.1 - 1.2e-35 122.7 153.7 1.2e-35 122.7 153.7 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain FATC PF02260.20 EAX95733.1 - 1e-10 41.2 1.2 5.2e-10 39.0 0.1 2.8 3 0 0 3 3 3 1 FATC domain HEAT PF02985.22 EAX95733.1 - 2.2e-06 27.4 2.2 0.14 12.5 0.0 6.1 8 0 0 8 8 8 1 HEAT repeat DUF3385 PF11865.8 EAX95733.1 - 0.00054 19.9 18.2 0.0035 17.3 1.7 5.8 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 EAX95733.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4042 PF13251.6 EAX95733.1 - 0.0048 16.6 0.0 0.35 10.6 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) FAT PF02259.23 EAX95733.1 - 0.017 14.3 0.4 0.035 13.3 0.4 1.5 1 0 0 1 1 1 0 FAT domain MTD PF01993.18 EAX95733.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HEAT_2 PF13646.6 EAX95733.1 - 0.1 13.0 0.0 31 5.1 0.0 3.3 2 1 0 3 3 3 0 HEAT repeats RIX1 PF08167.12 EAX95733.1 - 0.64 9.7 11.4 0.093 12.5 0.6 4.6 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Aldose_epim PF01263.20 EAX95735.1 - 3.4e-72 243.3 0.4 3.8e-72 243.1 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase WD40 PF00400.32 EAX95736.1 - 0.003 18.4 0.5 0.022 15.6 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Adeno_E3_CR1 PF02440.15 EAX95736.1 - 0.014 15.2 0.6 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 DUF4108 PF13390.6 EAX95737.1 - 1e-78 262.1 11.9 1.2e-78 261.9 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) VirK PF06903.12 EAX95738.1 - 0.032 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 VirK protein HI0933_like PF03486.14 EAX95740.1 - 0.25 10.0 0.6 0.25 10.0 0.6 1.0 1 0 0 1 1 1 0 HI0933-like protein DUF4108 PF13390.6 EAX95742.1 - 0.002 18.1 8.5 0.0022 17.9 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) YmgB PF10798.8 EAX95742.1 - 0.032 14.1 0.2 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF3839 PF12943.7 EAX95743.1 - 1e-78 264.2 10.5 1.3e-78 263.8 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Aminotran_1_2 PF00155.21 EAX95743.1 - 0.012 14.8 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2408 PF10303.9 EAX95743.1 - 0.029 14.9 0.9 0.048 14.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 EAX95743.1 - 0.036 14.5 0.6 0.043 14.3 0.6 1.1 1 0 0 1 1 1 0 Fez1 P4Ha_N PF08336.11 EAX95743.1 - 0.04 13.9 1.7 6.7 6.7 0.0 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4107 PF13389.6 EAX95746.1 - 8.8e-51 172.3 0.6 1e-50 172.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4106 PF13388.6 EAX95748.1 - 5.7e-259 859.3 18.9 5.7e-259 859.3 18.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX95748.1 - 0.0051 17.1 3.2 0.05 13.9 0.3 3.1 3 0 0 3 3 3 1 Kidney androgen-regulated WYL_3 PF18488.1 EAX95748.1 - 4 7.9 11.8 22 5.5 0.3 4.2 3 1 1 4 4 4 0 WYL domain DUF4108 PF13390.6 EAX95749.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX95751.1 - 3.6e-07 29.9 2.6 3.6e-07 29.9 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX95751.1 - 2.8e-05 24.4 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX95751.1 - 4.2e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX95751.1 - 0.00012 22.1 2.9 0.00028 20.9 2.9 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX95751.1 - 0.00053 19.8 0.1 0.00098 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX95751.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX95751.1 - 0.0014 18.4 0.8 0.0031 17.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX95751.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX95751.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX95751.1 - 0.091 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX95751.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX95751.1 - 0.41 10.9 4.2 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX95752.1 - 7.1e-16 58.0 1.2 1.5e-15 57.0 0.0 2.1 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX95752.1 - 0.0035 17.5 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF1493 PF07377.12 EAX95753.1 - 0.021 15.3 0.7 0.044 14.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX95754.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX95755.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP AAA_6 PF12774.7 EAX95758.1 - 3.1e-124 414.2 3.9 1.1e-119 399.2 0.0 3.4 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 EAX95758.1 - 1.7e-60 203.9 0.4 1.7e-60 203.9 0.4 3.4 3 0 0 3 3 2 1 ATP-binding dynein motor region DHC_N2 PF08393.13 EAX95758.1 - 9.5e-35 120.5 0.1 9.5e-35 120.5 0.1 3.9 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EAX95758.1 - 5.5e-34 117.1 0.1 1.7e-22 79.9 0.0 4.8 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAX95758.1 - 2.7e-31 108.5 3.0 6.6e-27 94.2 0.2 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 EAX95758.1 - 3.6e-27 94.8 0.0 2.9e-26 91.9 0.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EAX95758.1 - 4.5e-27 94.9 1.4 2.7e-26 92.3 0.1 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 EAX95758.1 - 2.8e-26 92.4 3.1 8.9e-26 90.8 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 MT PF12777.7 EAX95758.1 - 6e-26 91.3 10.0 6e-26 91.3 10.0 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EAX95758.1 - 2.4e-23 82.8 0.0 2.4e-23 82.8 0.0 2.5 3 0 0 3 3 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 EAX95758.1 - 1.4e-15 58.1 4.8 0.00052 20.4 0.0 6.2 6 0 0 6 6 4 3 AAA ATPase domain AAA_22 PF13401.6 EAX95758.1 - 2e-13 50.8 0.2 9.6e-05 22.7 0.1 4.4 3 0 0 3 3 3 3 AAA domain AAA PF00004.29 EAX95758.1 - 5.6e-11 43.0 0.1 0.023 15.1 0.0 4.8 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAX95758.1 - 4.1e-09 36.6 0.0 0.002 18.1 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 EAX95758.1 - 4.3e-09 36.4 0.1 0.018 14.8 0.0 4.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EAX95758.1 - 8.5e-09 36.0 0.0 0.042 14.4 0.0 4.5 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EAX95758.1 - 7.4e-08 32.8 0.3 0.00079 19.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EAX95758.1 - 2.6e-07 30.6 0.9 0.23 11.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EAX95758.1 - 8.4e-07 29.3 0.1 1 9.8 0.0 3.9 3 0 0 3 3 3 2 RNA helicase Rad17 PF03215.15 EAX95758.1 - 1.2e-06 28.6 0.9 0.0084 16.0 0.0 3.9 3 0 0 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EAX95758.1 - 1.2e-06 28.5 0.7 0.012 15.6 0.1 3.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EAX95758.1 - 1.2e-06 28.7 4.4 0.12 12.6 0.0 4.8 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 EAX95758.1 - 4.1e-06 26.4 0.1 0.032 14.0 0.0 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 EAX95758.1 - 5.9e-06 26.8 15.7 0.0029 18.1 0.0 5.1 5 1 0 5 5 2 2 ABC transporter TsaE PF02367.17 EAX95758.1 - 6.8e-06 26.1 0.9 1.4 8.9 0.0 4.7 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAX95758.1 - 1.1e-05 25.2 0.3 0.5 10.1 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_19 PF13245.6 EAX95758.1 - 1.4e-05 25.5 2.6 0.013 15.9 0.0 4.3 4 0 0 4 4 3 1 AAA domain CbiA PF01656.23 EAX95758.1 - 2.5e-05 24.3 0.0 2.5 8.2 0.0 4.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 EAX95758.1 - 6.3e-05 22.6 2.3 0.013 15.1 0.0 3.6 4 0 0 4 4 2 1 AAA domain Sigma54_activat PF00158.26 EAX95758.1 - 7.4e-05 22.5 0.0 0.016 14.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 EAX95758.1 - 7.6e-05 21.9 4.2 0.081 12.0 0.0 3.2 4 0 0 4 4 3 2 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAX95758.1 - 8.2e-05 22.1 0.2 0.22 10.9 0.1 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_lid_7 PF17867.1 EAX95758.1 - 0.00025 21.2 0.1 0.0014 18.8 0.0 2.4 2 0 0 2 2 1 1 Midasin AAA lid domain PRK PF00485.18 EAX95758.1 - 0.00041 20.1 0.5 0.38 10.4 0.0 3.7 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.14 EAX95758.1 - 0.002 17.4 0.3 0.19 10.8 0.1 2.8 2 0 0 2 2 2 1 PIF1-like helicase ATP_bind_1 PF03029.17 EAX95758.1 - 0.0021 17.9 3.9 7.1 6.3 0.0 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAX95758.1 - 0.0027 17.2 0.9 1.9 7.9 0.0 3.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EAX95758.1 - 0.0058 16.2 1.8 0.51 9.9 0.1 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EAX95758.1 - 0.0089 16.0 5.7 0.081 12.8 0.4 3.2 3 0 0 3 3 2 1 NTPase NB-ARC PF00931.22 EAX95758.1 - 0.011 14.9 0.3 3.6 6.7 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EAX95758.1 - 0.013 15.4 6.7 1.8 8.5 0.0 4.3 4 0 0 4 4 4 0 NACHT domain DUF3450 PF11932.8 EAX95758.1 - 0.014 14.7 23.2 0.25 10.6 5.6 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) MobB PF03205.14 EAX95758.1 - 0.022 14.6 1.1 5.2 7.0 0.2 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EAX95758.1 - 0.048 12.9 0.1 5.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin APS_kinase PF01583.20 EAX95758.1 - 0.059 13.3 0.7 0.82 9.5 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase ATPase_2 PF01637.18 EAX95758.1 - 0.065 13.1 0.0 0.065 13.1 0.0 4.4 6 0 0 6 6 3 0 ATPase domain predominantly from Archaea dNK PF01712.19 EAX95758.1 - 0.085 12.7 5.5 5 6.9 0.0 4.4 5 0 0 5 5 4 0 Deoxynucleoside kinase RuvB_N PF05496.12 EAX95758.1 - 0.12 12.1 0.1 14 5.4 0.0 3.3 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EAX95758.1 - 0.2 11.4 1.8 9.6 5.9 0.2 3.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EAX95758.1 - 0.35 10.5 9.8 0.35 10.5 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Guanylate_kin PF00625.21 EAX95758.1 - 1.6 8.4 5.1 6 6.5 0.0 3.2 3 0 0 3 3 2 0 Guanylate kinase ResIII PF04851.15 EAX95758.1 - 1.7 8.6 10.3 11 6.0 0.2 4.4 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EAX95758.1 - 1.7 9.1 38.7 2.1 8.8 0.4 6.7 7 0 0 7 7 6 0 AAA domain Spc7 PF08317.11 EAX95758.1 - 4.2 6.1 41.5 0.045 12.6 7.3 4.3 4 0 0 4 4 4 0 Spc7 kinetochore protein DHC_N1 PF08385.12 EAX95759.1 - 1.2e-16 60.5 9.1 1.2e-16 60.5 9.1 4.2 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DUF1664 PF07889.12 EAX95759.1 - 0.0075 16.3 0.7 0.0075 16.3 0.7 6.2 7 2 1 9 9 9 1 Protein of unknown function (DUF1664) Latarcin PF10279.9 EAX95759.1 - 0.012 16.0 0.0 0.96 9.9 0.0 3.8 3 2 0 3 3 3 0 Latarcin precursor AKAP28 PF14469.6 EAX95759.1 - 0.22 11.3 3.8 2.1 8.1 0.2 3.3 3 0 0 3 3 3 0 28 kDa A-kinase anchor Ank_4 PF13637.6 EAX95762.1 - 1.3e-28 98.9 2.3 3.6e-11 43.3 0.2 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95762.1 - 2e-27 95.6 6.4 4.1e-15 56.1 0.9 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95762.1 - 9.8e-23 79.5 0.0 7.5e-10 38.8 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX95762.1 - 6.9e-19 66.0 0.5 4e-07 29.8 0.1 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX95762.1 - 5.2e-16 58.5 0.4 1.8e-11 44.0 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 EAX95762.1 - 0.015 15.6 0.1 2.6 8.4 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein S6 DUF3718 PF12514.8 EAX95762.1 - 0.039 14.1 0.2 7 6.9 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3718) DUF3447 PF11929.8 EAX95763.1 - 2e-31 107.8 7.2 2e-31 107.8 7.2 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) AF0941-like PF14591.6 EAX95763.1 - 0.16 12.6 2.7 0.3 11.7 0.3 2.3 2 1 0 2 2 2 0 AF0941-like F5_F8_type_C PF00754.25 EAX95764.1 - 2.8e-08 33.9 0.1 6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Forkhead PF00250.18 EAX95766.1 - 0.059 13.6 1.7 0.14 12.4 0.4 2.1 2 0 0 2 2 2 0 Forkhead domain HhH-GPD PF00730.25 EAX95767.1 - 0.16 12.4 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein IBR PF01485.21 EAX95768.1 - 6.3e-06 26.3 17.7 6.3e-06 26.3 17.7 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Gly_rich PF12810.7 EAX95769.1 - 3.2e-12 46.9 25.1 4.4e-12 46.5 25.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX95770.1 - 1e-38 133.7 37.0 1.2e-38 133.5 37.0 1.0 1 0 0 1 1 1 1 Glycine rich protein ZapB PF06005.12 EAX95771.1 - 0.015 15.7 5.5 0.015 15.7 5.5 9.3 5 2 2 7 7 7 0 Cell division protein ZapB MtrG PF04210.13 EAX95771.1 - 2.1 8.3 4.2 12 5.9 0.4 3.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Sugar_tr PF00083.24 EAX95772.1 - 9.9e-35 120.3 42.4 7.4e-22 77.8 17.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX95772.1 - 6.7e-17 61.4 42.6 6.7e-17 61.4 42.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CtsR_C PF17727.1 EAX95774.1 - 0.11 12.6 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Synaptobrevin PF00957.21 EAX95775.1 - 2.2e-25 88.2 1.6 3.4e-25 87.7 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAX95775.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Laminin_II PF06009.12 EAX95775.1 - 0.047 13.7 3.4 0.081 12.9 1.8 1.8 2 0 0 2 2 2 0 Laminin Domain II Pex24p PF06398.11 EAX95775.1 - 0.056 12.4 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.18 EAX95775.1 - 0.11 12.7 0.3 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L38e protein family Beach PF02138.18 EAX95776.1 - 2.8e-98 328.7 0.1 6.1e-98 327.6 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX95776.1 - 2e-05 24.6 0.0 5.9e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EAX95776.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF5407 PF17401.2 EAX95776.1 - 0.026 14.8 0.3 0.092 13.0 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5407) DUF4800 PF16057.5 EAX95776.1 - 0.037 13.3 0.2 0.082 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) AAA_14 PF13173.6 EAX95776.1 - 0.079 13.0 0.0 0.079 13.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain Synaptobrevin PF00957.21 EAX95777.1 - 6.3e-29 99.6 5.9 7.3e-29 99.4 5.0 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EAX95777.1 - 2e-06 27.7 0.2 4.7e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Beta_lactamase3 PF17030.5 EAX95777.1 - 0.0054 16.0 1.2 0.0079 15.5 0.9 1.4 1 1 0 1 1 1 1 Putative beta-lactamase-like family Ferlin_C PF16165.5 EAX95777.1 - 0.0065 16.4 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Ferlin C-terminus Vac14_Fab1_bd PF12755.7 EAX95777.1 - 0.025 15.2 0.3 5 7.8 0.1 2.8 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region CbiG_mid PF11761.8 EAX95777.1 - 0.049 13.8 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Cnl2_NKP2 PF09447.10 EAX95777.1 - 0.063 13.4 0.4 0.15 12.2 0.4 1.8 1 1 0 1 1 1 0 Cnl2/NKP2 family protein Fzo_mitofusin PF04799.13 EAX95777.1 - 0.11 12.0 3.0 0.28 10.7 3.0 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF802 PF05650.11 EAX95777.1 - 0.67 10.5 3.4 1.6 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Ras PF00071.22 EAX95778.1 - 2.7e-37 127.9 0.0 3.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX95778.1 - 5.6e-29 100.8 0.0 8.3e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX95778.1 - 8.3e-07 28.6 0.0 9.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX95778.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX95778.1 - 5.4e-06 26.2 0.0 4.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EAX95778.1 - 0.00018 21.6 0.0 0.00047 20.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EAX95778.1 - 0.00056 19.3 0.0 0.76 9.0 0.0 2.1 2 0 0 2 2 2 2 Septin GTP_EFTU PF00009.27 EAX95778.1 - 0.0012 18.4 0.1 0.01 15.4 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EAX95778.1 - 0.0043 16.4 0.0 0.85 8.9 0.0 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EAX95778.1 - 0.0048 16.8 0.2 0.46 10.4 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase PSP PF04046.16 EAX95779.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX95780.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX95781.1 - 0.033 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KIND PF16474.5 EAX95782.1 - 0.082 12.8 0.2 0.095 12.6 0.2 1.1 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Atx10homo_assoc PF09759.9 EAX95783.1 - 0.0043 17.0 0.2 0.04 13.9 0.0 2.4 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Clat_adaptor_s PF01217.20 EAX95784.1 - 0.16 11.9 2.4 0.69 9.8 0.2 2.6 2 1 1 3 3 3 0 Clathrin adaptor complex small chain Zn_peptidase_2 PF04298.12 EAX95785.1 - 0.021 14.3 0.0 0.051 13.0 0.1 1.5 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase LRR_5 PF13306.6 EAX95786.1 - 6.4e-93 307.4 147.9 1.5e-20 73.5 10.8 9.2 1 1 7 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95786.1 - 2.8e-22 78.2 43.4 1.1e-05 25.1 4.5 15.2 6 3 11 17 17 17 11 Leucine rich repeat LRR_4 PF12799.7 EAX95786.1 - 1e-05 25.7 79.6 0.47 11.0 1.8 16.0 10 5 7 18 18 18 9 Leucine Rich repeats (2 copies) dNK PF01712.19 EAX95787.1 - 3.6e-17 62.9 0.0 9.1e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 EAX95787.1 - 9.9e-12 45.5 0.0 9.4e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 EAX95787.1 - 5.5e-07 29.8 0.0 0.0089 16.2 0.0 2.3 2 1 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 EAX95787.1 - 7.2e-05 23.0 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EAX95787.1 - 9.8e-05 22.3 0.1 0.00052 20.0 0.1 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 EAX95787.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 EAX95787.1 - 0.0015 18.3 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EAX95787.1 - 0.0023 18.2 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX95787.1 - 0.0024 18.2 0.1 0.0069 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EAX95787.1 - 0.003 17.3 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_17 PF13207.6 EAX95787.1 - 0.0037 17.7 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EAX95787.1 - 0.0066 15.5 0.0 0.16 11.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.15 EAX95787.1 - 0.011 15.6 0.1 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 EAX95787.1 - 0.015 15.8 0.8 0.027 15.0 0.5 1.8 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 EAX95787.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EAX95787.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 EAX95787.1 - 0.023 14.8 0.0 0.098 12.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 EAX95787.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EAX95787.1 - 0.038 14.4 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 EAX95787.1 - 0.051 13.3 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EAX95787.1 - 0.071 12.7 0.2 0.42 10.2 0.2 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase1 PF18748.1 EAX95787.1 - 0.08 12.5 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Guanylate_kin PF00625.21 EAX95787.1 - 0.1 12.3 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_5 PF07728.14 EAX95787.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 EAX95787.1 - 0.16 11.4 0.1 9.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cullin PF00888.22 EAX95788.1 - 2.4e-39 135.5 6.6 3.5e-38 131.6 6.6 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAX95788.1 - 4.3e-07 29.9 0.3 2e-06 27.7 0.3 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF148 PF02520.17 EAX95788.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 Nitroreductase PF00881.24 EAX95789.1 - 2.3e-33 115.6 0.0 2.7e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX95789.1 - 0.00016 21.3 0.2 0.0025 17.4 0.4 2.3 1 1 1 2 2 2 1 Putative TM nitroreductase DUF4358 PF14270.6 EAX95789.1 - 0.044 14.1 0.7 0.065 13.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Actin PF00022.19 EAX95790.1 - 4.6e-97 325.2 0.0 2.2e-96 323.0 0.0 1.7 1 1 0 1 1 1 1 Actin PTAC PF06130.12 EAX95791.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphate propanoyltransferase Actin PF00022.19 EAX95792.1 - 4.6e-97 325.2 0.0 2.2e-96 323.0 0.0 1.7 1 1 0 1 1 1 1 Actin LRR_5 PF13306.6 EAX95793.1 - 6.8e-23 81.0 31.4 2.9e-08 33.7 1.2 3.7 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95793.1 - 0.0013 18.5 3.2 1.7 8.4 0.0 4.0 4 0 0 4 4 4 2 Leucine rich repeat Ank_2 PF12796.7 EAX95794.1 - 6.8e-100 327.8 73.9 1.2e-16 61.0 1.1 9.3 3 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95794.1 - 1.4e-89 291.0 22.6 1.5e-08 34.7 0.0 13.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.6 EAX95794.1 - 6.2e-79 259.4 20.1 3.9e-12 46.4 0.0 13.2 6 2 9 15 15 15 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95794.1 - 3.9e-70 231.0 44.9 2.9e-11 43.4 0.3 11.9 5 2 9 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95794.1 - 1e-67 216.0 32.3 2.8e-06 27.2 0.0 15.1 15 0 0 15 15 15 13 Ankyrin repeat DUF3447 PF11929.8 EAX95794.1 - 2.9e-21 75.2 4.2 2.9e-21 75.2 4.2 7.7 7 1 2 9 9 9 2 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX95794.1 - 8.7e-05 22.7 3.0 10 6.4 0.0 6.6 4 2 3 7 7 7 1 N terminal of Calcineurin-like phosphoesterase Ribosomal_S6 PF01250.17 EAX95794.1 - 0.68 10.2 7.4 38 4.6 0.1 4.8 4 1 0 4 4 4 0 Ribosomal protein S6 RNase_PH_C PF03725.15 EAX95794.1 - 0.9 9.6 11.0 7.8 6.6 0.0 5.8 3 3 3 6 6 6 0 3' exoribonuclease family, domain 2 LigB PF02900.18 EAX95794.1 - 0.99 8.4 7.0 2.3 7.2 0.4 3.2 2 1 1 3 3 3 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase SAB PF04382.13 EAX95794.1 - 1.8 8.7 5.3 1.8e+02 2.3 0.0 4.8 5 0 0 5 5 5 0 SAB domain DUF4140 PF13600.6 EAX95795.1 - 0.11 13.0 10.7 0.48 10.9 0.2 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ac76 PF05814.11 EAX95795.1 - 0.57 10.2 7.8 0.74 9.9 0.7 3.1 2 1 0 2 2 2 0 Orf76 (Ac76) PMC2NT PF08066.12 EAX95795.1 - 0.94 10.2 9.7 2 9.2 0.1 3.8 3 2 3 6 6 6 0 PMC2NT (NUC016) domain DUF4407 PF14362.6 EAX95795.1 - 1.9 7.7 20.4 0.62 9.4 1.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) ApoO PF09769.9 EAX95795.1 - 3.7 7.5 12.2 16 5.5 0.5 4.1 2 2 2 4 4 4 0 Apolipoprotein O SlyX PF04102.12 EAX95795.1 - 4.7 7.9 18.3 2.8 8.6 1.7 4.3 3 1 0 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 EAX95795.1 - 8.8 6.4 30.8 1.7 8.7 10.5 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein C9orf72-like PF15019.6 EAX95796.1 - 1.3e-59 201.7 6.4 2e-59 201.1 6.4 1.2 1 0 0 1 1 1 1 C9orf72-like protein family Zn_ribbon_17 PF17120.5 EAX95797.1 - 8.7e-05 22.1 7.6 0.00022 20.8 7.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD_3 PF13922.6 EAX95797.1 - 0.00076 19.8 2.7 0.0023 18.3 2.7 1.8 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx Vps39_2 PF10367.9 EAX95797.1 - 0.0037 17.7 0.6 0.01 16.3 0.6 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Coatomer_WDAD PF04053.14 EAX95797.1 - 0.022 13.8 0.7 13 4.7 0.1 3.7 4 0 0 4 4 4 0 Coatomer WD associated region Cas6b_C PF17262.2 EAX95797.1 - 0.023 14.8 0.5 0.092 12.9 0.2 2.2 2 0 0 2 2 2 0 Cas6b C-terminal domain zf-RING_2 PF13639.6 EAX95797.1 - 0.027 14.8 12.6 0.077 13.3 12.6 1.9 1 1 0 1 1 1 0 Ring finger domain Clathrin PF00637.20 EAX95797.1 - 0.034 14.0 0.5 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS Zf_RING PF16744.5 EAX95797.1 - 0.28 11.3 5.6 0.63 10.2 5.6 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 EAX95797.1 - 0.98 9.4 11.5 2.7 8.0 11.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 EAX95797.1 - 1.7 8.7 11.6 4.3 7.4 11.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain C1_2 PF03107.16 EAX95797.1 - 3.7 7.9 12.0 1.9 8.8 9.2 2.0 2 0 0 2 2 2 0 C1 domain GTP_EFTU_D3 PF03143.17 EAX95798.1 - 1.1e-40 138.4 0.0 1.6e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAX95798.1 - 0.015 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Semialdhyde_dhC PF02774.18 EAX95798.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.27 EAX95799.1 - 7e-53 179.1 0.0 9.1e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX95799.1 - 3.6e-08 33.5 0.1 1.4e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX95799.1 - 0.00052 19.5 0.2 0.0017 17.8 0.2 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAX95799.1 - 0.002 18.3 0.6 0.043 14.0 0.1 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX95799.1 - 0.011 15.4 0.8 0.042 13.5 0.1 2.1 2 1 0 2 2 2 0 Ras family FlpD PF02662.16 EAX95799.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit G-alpha PF00503.20 EAX95799.1 - 0.04 13.1 0.2 2.5 7.2 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Septin PF00735.18 EAX95799.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Septin Arf PF00025.21 EAX95799.1 - 0.092 12.2 0.3 3.7 7.0 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family ATP-synt PF00231.19 EAX95799.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase adh_short PF00106.25 EAX95800.1 - 6.7e-25 87.7 0.0 8.2e-24 84.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAX95800.1 - 8.9e-18 64.7 0.0 1.4e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAX95800.1 - 1.5e-05 24.9 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain SHIPPO-rpt PF07004.12 EAX95801.1 - 6.7e-09 36.3 20.6 0.11 13.4 0.0 8.3 8 0 0 8 8 8 5 Sperm-tail PG-rich repeat Myb_DNA-binding PF00249.31 EAX95802.1 - 5e-25 87.4 0.9 7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95802.1 - 1.8e-22 79.3 2.7 1.3e-15 57.4 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX95802.1 - 0.0002 21.2 2.6 0.00026 20.8 0.3 2.1 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX95802.1 - 0.00063 19.7 0.6 0.34 11.0 0.1 2.7 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX95802.1 - 0.00092 19.3 0.4 0.047 13.8 0.0 2.1 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX95802.1 - 0.0014 18.7 0.5 0.28 11.4 0.1 2.9 1 1 1 2 2 2 1 Rap1 Myb domain GIY-YIG PF01541.24 EAX95802.1 - 0.068 13.5 0.4 1.8 8.9 0.0 2.4 1 1 1 2 2 2 0 GIY-YIG catalytic domain F-box-like_2 PF13013.6 EAX95802.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain YceG PF02618.16 EAX95802.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 YceG-like family SANT_DAMP1_like PF16282.5 EAX95802.1 - 0.11 12.7 1.9 0.36 11.1 0.2 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 NT-C2 PF10358.9 EAX95803.1 - 2.1e-20 72.9 1.8 2.1e-20 72.9 1.8 3.6 3 0 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins T5orf172 PF10544.9 EAX95804.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain EF-hand_10 PF14788.6 EAX95805.1 - 0.0013 18.6 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 EF hand GPS2_interact PF15784.5 EAX95807.1 - 0.05 14.0 1.3 0.067 13.6 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX95807.1 - 0.14 11.1 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF2341 PF10102.9 EAX95808.1 - 0.062 13.9 0.2 0.1 13.2 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2341) Radial_spoke_3 PF06098.11 EAX95809.1 - 1e-62 212.0 22.3 1e-62 212.0 22.3 2.5 1 1 2 3 3 3 1 Radial spoke protein 3 DUF775 PF05603.12 EAX95809.1 - 0.023 14.2 0.1 0.023 14.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF775) Pkinase_Tyr PF07714.17 EAX95810.1 - 9.4e-57 192.2 0.0 1.8e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95810.1 - 7.9e-56 189.3 0.0 1.6e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAX95810.1 - 0.0039 16.0 0.0 0.0077 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX95810.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family DUF5063 PF16702.5 EAX95810.1 - 0.17 12.2 0.7 14 6.0 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5063) Adaptin_N PF01602.20 EAX95812.1 - 9.2e-73 245.6 11.9 1.3e-72 245.1 11.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX95812.1 - 0.00081 19.5 2.0 0.077 13.0 0.0 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HAUS4 PF14735.6 EAX95812.1 - 0.005 16.6 0.2 0.009 15.7 0.2 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 RICTOR_M PF14666.6 EAX95812.1 - 0.021 14.6 0.1 0.24 11.2 0.2 3.0 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain HEAT_2 PF13646.6 EAX95812.1 - 0.023 15.1 0.1 17 5.9 0.1 4.0 4 0 0 4 4 4 0 HEAT repeats DNA_alkylation PF08713.11 EAX95812.1 - 0.024 14.4 0.0 0.67 9.6 0.0 2.5 1 1 1 2 2 2 0 DNA alkylation repair enzyme Alpha_adaptinC2 PF02883.20 EAX95812.1 - 0.027 14.8 1.5 0.06 13.7 0.1 2.2 2 0 0 2 2 2 0 Adaptin C-terminal domain CRS1_YhbY PF01985.21 EAX95812.1 - 0.073 13.2 0.3 0.65 10.2 0.1 2.5 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain YL1 PF05764.13 EAX95812.1 - 0.094 12.8 7.2 0.16 12.0 7.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cnd3 PF12719.7 EAX95812.1 - 0.18 11.0 4.5 0.39 9.9 0.5 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Acyltransferase PF01553.21 EAX95813.1 - 4.2e-08 32.9 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ASH PF15780.5 EAX95814.1 - 8.6e-12 45.1 9.3 0.00014 22.0 0.1 5.3 4 1 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 EAX95814.1 - 3.2e-05 24.1 0.5 0.3 11.3 0.0 4.6 5 0 0 5 5 5 2 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD-like PF14874.6 EAX95814.1 - 0.00069 19.7 0.2 0.29 11.3 0.0 3.2 3 0 0 3 3 3 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EAX95814.1 - 0.0015 18.4 9.2 0.086 12.7 0.0 4.8 5 0 0 5 5 5 2 MSP (Major sperm protein) domain Herpes_UL42 PF02282.16 EAX95814.1 - 0.013 15.4 2.2 0.021 14.7 0.1 2.4 3 0 0 3 3 3 0 DNA polymerase processivity factor (UL42) VasI PF11319.8 EAX95814.1 - 0.061 13.0 0.4 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 TPR_MLP1_2 PF07926.12 EAX95815.1 - 0.0014 18.7 45.8 0.0037 17.3 5.0 4.2 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EAX95815.1 - 0.0089 16.6 46.5 0.16 12.5 10.9 4.1 1 1 4 5 5 5 2 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 EAX95815.1 - 0.0095 15.5 16.9 0.0095 15.5 16.9 2.8 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 EAX95815.1 - 0.012 15.5 18.2 0.012 15.5 18.2 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EAX95815.1 - 0.025 14.8 40.8 0.06 13.6 16.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.21 EAX95815.1 - 0.03 13.9 41.5 0.34 10.4 19.5 3.3 1 1 2 3 3 3 0 Intermediate filament protein Lebercilin PF15619.6 EAX95815.1 - 0.047 13.4 52.3 0.18 11.5 7.4 4.1 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease FAM184 PF15665.5 EAX95815.1 - 0.048 13.4 42.9 0.89 9.3 21.2 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 EAX95815.1 - 0.07 13.2 50.3 0.42 10.6 8.8 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EAX95815.1 - 0.09 12.9 50.9 0.62 10.1 12.1 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EAX95815.1 - 0.13 11.1 49.2 0.81 8.5 15.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4686 PF15742.5 EAX95815.1 - 0.14 11.3 52.4 1.9 7.5 32.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) MAD PF05557.13 EAX95815.1 - 0.2 10.0 50.9 0.022 13.1 23.4 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4715 PF15835.5 EAX95815.1 - 0.31 11.1 14.3 0.96 9.5 0.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4715) YtxH PF12732.7 EAX95815.1 - 0.95 10.0 13.8 1.2e+04 -3.1 13.8 4.3 1 1 0 1 1 0 0 YtxH-like protein DUF4201 PF13870.6 EAX95815.1 - 0.96 9.2 46.0 0.099 12.4 9.1 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EAX95815.1 - 1.1 9.3 31.9 2.4 8.2 9.7 3.8 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EAX95815.1 - 1.1 6.7 39.3 3.7 4.9 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ERM PF00769.19 EAX95815.1 - 1.1 9.0 39.8 0.25 11.1 26.6 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FUSC PF04632.12 EAX95815.1 - 1.3 7.5 2.2 16 3.9 1.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family JIP_LZII PF16471.5 EAX95815.1 - 1.4 9.2 31.7 0.65 10.2 0.9 5.5 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 EAX95815.1 - 2.2 8.6 41.6 0.4 11.0 15.0 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) MscS_porin PF12795.7 EAX95815.1 - 3.2 7.2 43.1 0.53 9.8 12.9 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Cep57_CLD_2 PF14197.6 EAX95815.1 - 4 7.6 38.8 1.6 8.9 1.0 5.8 2 1 2 5 5 4 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 EAX95815.1 - 4 7.8 45.2 0.043 14.3 21.4 3.1 1 1 3 4 4 4 0 Fez1 DUF4279 PF14106.6 EAX95815.1 - 4.2 7.6 9.2 0.31 11.2 1.0 2.9 1 1 2 4 4 4 0 Domain of unknown function (DUF4279) Fib_alpha PF08702.10 EAX95815.1 - 4.6 7.4 46.3 0.23 11.6 11.1 3.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 EAX95815.1 - 4.6 7.6 14.3 1.8 8.9 1.5 4.1 4 1 1 5 5 4 0 Proteins of 100 residues with WXG SHE3 PF17078.5 EAX95815.1 - 5.1 6.7 48.6 0.25 11.0 24.5 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4618 PF15397.6 EAX95815.1 - 6.3 6.1 45.7 5.2 6.4 6.0 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) HalX PF08663.10 EAX95815.1 - 7.7 6.9 15.1 5.4 7.4 0.1 4.3 3 2 2 5 5 4 0 HalX domain DUF2203 PF09969.9 EAX95815.1 - 9.2 7.0 25.8 7.3 7.3 6.0 3.5 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) PRKG1_interact PF15898.5 EAX95815.1 - 9.8 7.1 47.1 2.6 9.0 15.1 4.2 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 EAX95815.1 - 10 6.6 36.8 1.7 9.1 0.9 6.1 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Ank_5 PF13857.6 EAX95816.1 - 2.7e-68 225.1 31.5 1.6e-11 44.2 0.2 6.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95816.1 - 2.9e-66 219.0 23.2 4.3e-14 52.7 0.2 8.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95816.1 - 5.1e-66 219.3 30.9 2.4e-16 60.1 0.9 5.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95816.1 - 6.2e-65 213.0 21.3 1.1e-07 31.9 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAX95816.1 - 2.8e-57 183.9 15.3 1.6e-06 28.0 0.0 7.5 8 0 0 8 8 7 7 Ankyrin repeat ThiS-like PF14453.6 EAX95816.1 - 7.1e-11 42.0 13.6 1.5 9.0 0.1 7.1 2 1 5 7 7 7 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAX95816.1 - 1.9e-08 34.5 0.0 0.11 12.7 0.0 4.3 1 1 4 5 5 5 5 N terminal of Calcineurin-like phosphoesterase DUF3863 PF12979.7 EAX95816.1 - 4.9e-07 28.9 2.9 0.022 13.6 0.0 3.0 1 1 2 3 3 3 3 Domain of Unknown Function with PDB structure (DUF3863) CEP44 PF15007.6 EAX95816.1 - 1.8e-06 28.2 0.1 90 3.2 0.0 6.4 1 1 5 7 7 7 0 Centrosomal spindle body, CEP44 CCG PF02754.16 EAX95816.1 - 4.3e-05 23.6 3.9 0.26 11.5 0.1 4.7 1 1 2 4 4 4 1 Cysteine-rich domain Fer2 PF00111.27 EAX95816.1 - 0.00016 21.5 1.3 1.2e+02 2.8 0.0 6.3 7 0 0 7 7 7 0 2Fe-2S iron-sulfur cluster binding domain RRP7 PF12923.7 EAX95816.1 - 0.0022 18.1 3.7 3.3 7.9 0.6 3.7 1 1 2 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DHFR_1 PF00186.19 EAX95816.1 - 0.0067 16.1 0.4 18 5.0 0.0 3.4 1 1 4 5 5 5 0 Dihydrofolate reductase DUF3340 PF11818.8 EAX95816.1 - 0.0079 16.4 10.3 3 8.0 2.4 4.1 1 1 3 4 4 4 2 C-terminal domain of tail specific protease (DUF3340) Ribosomal_S6 PF01250.17 EAX95816.1 - 0.017 15.4 4.2 39 4.6 0.0 4.7 1 1 4 5 5 5 0 Ribosomal protein S6 DUF2149 PF09919.9 EAX95816.1 - 0.04 14.2 8.9 1.9e+02 2.4 0.0 6.2 1 1 6 7 7 7 0 Uncharacterized conserved protein (DUF2149) Tudor_2 PF18104.1 EAX95816.1 - 0.56 9.9 4.0 2.2e+02 1.6 0.1 5.2 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain Ank_4 PF13637.6 EAX95817.1 - 4.1e-51 170.7 13.5 5.7e-13 49.1 0.2 7.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95817.1 - 3e-45 152.7 22.4 3.1e-17 62.9 4.4 5.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95817.1 - 2.3e-44 148.0 14.6 1.4e-07 31.6 0.0 7.5 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAX95817.1 - 2.7e-42 137.9 12.9 1.9e-06 27.7 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX95817.1 - 5.9e-36 122.1 10.5 1.4e-11 44.4 0.1 5.7 3 2 3 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX95817.1 - 1.1e-33 115.0 10.0 1.1e-33 115.0 10.0 4.1 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) ThiS-like PF14453.6 EAX95817.1 - 6.4e-07 29.3 4.8 6.2 6.9 0.2 5.7 3 1 2 5 5 5 1 ThiS-like ubiquitin MetallophosN PF16371.5 EAX95817.1 - 0.00013 22.2 0.0 0.5 10.7 0.0 2.9 1 1 2 3 3 3 2 N terminal of Calcineurin-like phosphoesterase CCG PF02754.16 EAX95817.1 - 0.0021 18.2 0.6 0.29 11.4 0.1 3.1 1 1 2 3 3 3 1 Cysteine-rich domain DUF3340 PF11818.8 EAX95817.1 - 0.011 15.9 2.4 7.4 6.7 0.2 3.2 1 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) RRP7 PF12923.7 EAX95817.1 - 0.019 15.1 0.2 1.3 9.2 0.2 2.4 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3863 PF12979.7 EAX95817.1 - 0.029 13.2 0.8 0.34 9.7 0.2 2.2 1 1 2 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3863) Fer2 PF00111.27 EAX95817.1 - 0.11 12.5 0.5 1.1e+02 2.8 0.0 4.4 5 0 0 5 5 5 0 2Fe-2S iron-sulfur cluster binding domain RL PF17797.1 EAX95817.1 - 0.19 11.7 1.1 1.7 8.7 0.3 2.7 2 1 0 2 2 2 0 RL domain WD40 PF00400.32 EAX95818.1 - 1.3e-31 108.1 6.6 0.00034 21.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95818.1 - 7.2e-14 51.9 0.1 0.04 14.2 0.0 5.6 1 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX95818.1 - 1.7e-05 24.0 1.9 0.15 11.0 0.1 4.2 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 EAX95818.1 - 3.1e-05 22.8 0.1 0.1 11.2 0.0 2.6 2 1 1 3 3 3 2 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 EAX95818.1 - 3.8e-05 23.6 0.9 0.087 12.7 0.0 3.9 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EAX95818.1 - 9.7e-05 21.2 1.8 0.61 8.7 0.1 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EAX95818.1 - 0.0043 16.4 0.2 0.04 13.2 0.0 2.4 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF948 PF06103.11 EAX95818.1 - 0.0056 16.9 2.9 0.013 15.7 2.9 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF2205 PF10224.9 EAX95818.1 - 0.012 15.6 4.6 0.022 14.7 4.6 1.4 1 0 0 1 1 1 0 Short coiled-coil protein DUF1664 PF07889.12 EAX95818.1 - 0.015 15.4 3.4 0.027 14.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EAX95818.1 - 0.022 15.1 3.8 0.049 13.9 3.8 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 EAX95818.1 - 0.022 15.5 3.5 0.037 14.7 3.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Hormone_1 PF00103.20 EAX95818.1 - 0.024 14.4 2.0 0.043 13.6 2.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Baculo_PEP_C PF04513.12 EAX95818.1 - 0.041 13.9 4.6 0.12 12.4 4.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 EAX95818.1 - 0.047 14.0 8.3 0.077 13.3 8.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 EAX95818.1 - 0.049 13.6 10.9 0.084 12.9 10.9 1.3 1 0 0 1 1 1 0 FlxA-like protein XRN_M PF17846.1 EAX95818.1 - 0.05 12.5 2.1 0.078 11.9 2.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain YkyA PF10368.9 EAX95818.1 - 0.051 13.2 10.2 0.11 12.1 10.2 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein APG6_N PF17675.1 EAX95818.1 - 0.055 14.0 9.9 0.091 13.3 9.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EAX95818.1 - 0.084 12.2 8.2 0.14 11.4 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 EAX95818.1 - 0.13 12.7 5.4 0.25 11.8 5.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HrpB7 PF09486.10 EAX95818.1 - 0.14 12.6 3.6 0.21 11.9 3.6 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FliD_C PF07195.12 EAX95818.1 - 0.14 11.6 7.3 0.27 10.6 7.3 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2353 PF09789.9 EAX95818.1 - 0.16 11.3 8.5 0.24 10.7 8.5 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WD40_like PF17005.5 EAX95818.1 - 0.16 11.2 8.1 0.28 10.4 0.0 3.5 3 2 1 4 4 4 0 WD40-like domain CENP-O PF09496.10 EAX95818.1 - 0.17 11.9 1.5 0.27 11.2 1.5 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DHR10 PF18595.1 EAX95818.1 - 0.18 11.9 10.3 0.31 11.1 10.3 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 EAX95818.1 - 0.18 11.0 4.7 0.27 10.4 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFT57 PF10498.9 EAX95818.1 - 0.19 10.7 7.0 0.29 10.1 7.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 EAX95818.1 - 0.21 10.4 7.5 0.31 9.9 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 EAX95818.1 - 0.33 11.6 7.5 0.64 10.6 7.5 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 FapA PF03961.13 EAX95818.1 - 0.35 9.4 4.7 0.51 8.9 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hrs_helical PF12210.8 EAX95818.1 - 0.36 11.4 4.3 1 10.0 4.4 1.7 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate HIP1_clath_bdg PF16515.5 EAX95818.1 - 0.77 10.4 7.6 1.3 9.7 7.6 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 EAX95818.1 - 0.86 10.3 5.4 1.8 9.2 5.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF4446 PF14584.6 EAX95818.1 - 1.2 9.1 5.6 0.5 10.4 1.0 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) Fzo_mitofusin PF04799.13 EAX95818.1 - 1.3 8.5 4.4 2.5 7.6 4.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4407 PF14362.6 EAX95818.1 - 1.3 8.3 5.3 2 7.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EAX95818.1 - 1.7 7.7 7.8 2.6 7.0 7.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EAX95818.1 - 2.1 8.5 12.5 3.3 7.9 12.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CorA PF01544.18 EAX95818.1 - 2.4 7.4 6.1 4.3 6.6 6.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMF_DNA_bd PF12329.8 EAX95818.1 - 2.9 7.9 9.4 0.69 10.0 3.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Nbl1_Borealin_N PF10444.9 EAX95818.1 - 9.4 6.0 8.4 3 7.5 0.3 2.3 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal DivIC PF04977.15 EAX95818.1 - 9.8 6.0 13.3 19 5.1 0.7 2.4 1 1 1 2 2 2 0 Septum formation initiator YgbB PF02542.16 EAX95819.1 - 1.1 9.6 6.7 0.49 10.7 0.4 3.0 2 2 1 3 3 3 0 YgbB family YvrJ PF12841.7 EAX95819.1 - 1.1 8.8 2.7 3 7.5 1.4 2.5 2 0 0 2 2 2 0 YvrJ protein family DASH_Dam1 PF08653.10 EAX95819.1 - 9.9 6.1 8.4 46 3.9 0.1 4.5 4 1 1 5 5 5 0 DASH complex subunit Dam1 Bromodomain PF00439.25 EAX95820.1 - 1.4e-05 25.1 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX95820.1 - 0.11 12.6 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation APC_N_CC PF16689.5 EAX95821.1 - 0.085 12.9 0.3 0.085 12.9 0.3 4.4 6 0 0 6 6 6 0 Coiled-coil N-terminus of APC, dimerisation domain Ank_2 PF12796.7 EAX95822.1 - 6.7e-20 71.5 0.4 2.5e-11 44.0 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95822.1 - 2.4e-11 43.7 1.2 3.8e-05 23.9 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95822.1 - 2.8e-11 43.7 0.6 0.0032 18.0 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX95822.1 - 3.6e-09 36.5 5.5 7.2e-09 35.5 2.2 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX95822.1 - 1.2e-08 35.0 0.7 0.1 13.1 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX95822.1 - 6.5e-08 32.3 1.0 0.19 12.4 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Sas10_Utp3 PF04000.15 EAX95822.1 - 0.056 14.1 0.7 0.19 12.4 0.0 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family zf-UDP PF14569.6 EAX95822.1 - 0.12 12.5 0.3 0.12 12.5 0.3 1.6 2 0 0 2 2 2 0 Zinc-binding RING-finger Spc7 PF08317.11 EAX95823.1 - 0.0003 19.8 51.7 0.004 16.1 22.5 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein NPV_P10 PF05531.12 EAX95823.1 - 0.18 12.3 24.2 2.4 8.7 7.6 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein SLX9 PF15341.6 EAX95823.1 - 0.2 12.0 34.4 0.023 15.1 13.6 3.1 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 EAX95823.1 - 0.43 10.8 51.9 0.063 13.5 7.7 4.2 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EAX95823.1 - 0.61 10.1 33.6 0.99 9.5 2.8 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EAX95823.1 - 0.69 8.9 47.3 0.093 11.8 21.1 3.4 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3138 PF11336.8 EAX95823.1 - 0.91 8.1 3.0 1.5 7.3 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.9 EAX95823.1 - 0.96 9.8 44.0 6.9 7.0 15.5 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.11 EAX95823.1 - 2.7 6.6 45.2 0.77 8.4 23.9 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light ATG16 PF08614.11 EAX95823.1 - 2.9 8.1 45.6 18 5.5 21.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EAX95823.1 - 6.3 5.6 48.2 12 4.7 1.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 EAX95823.1 - 9.1 5.8 44.2 0.17 11.4 13.4 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4159 PF13709.6 EAX95824.1 - 0.12 11.8 0.3 0.16 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Got1 PF04178.12 EAX95825.1 - 1.6e-08 34.9 9.6 2.3e-08 34.4 9.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 EAX95825.1 - 1 9.7 15.4 5.1 7.5 9.4 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PALP PF00291.25 EAX95826.1 - 4.6e-74 249.5 0.1 5.5e-74 249.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsA PF14450.6 EAX95826.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA DUF1493 PF07377.12 EAX95827.1 - 0.035 14.6 0.6 0.073 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX95828.1 - 0.018 15.4 2.5 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Phos_pyr_kin PF08543.12 EAX95829.1 - 8.8e-18 64.6 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EAX95829.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pkinase PF00069.25 EAX95831.1 - 4.9e-60 203.1 0.0 5.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95831.1 - 5.1e-37 127.6 0.0 6.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95831.1 - 7.3e-08 32.1 0.0 5.1e-07 29.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EAX95831.1 - 0.0024 16.9 1.1 0.032 13.2 0.0 2.7 3 0 0 3 3 3 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EAX95831.1 - 0.057 13.0 0.7 8.5 5.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX95831.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_5 PF13306.6 EAX95832.1 - 3.2e-15 56.2 0.4 3.2e-15 56.2 0.4 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) DUF2179 PF10035.9 EAX95832.1 - 0.03 14.1 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) LRR_5 PF13306.6 EAX95833.1 - 4.2e-50 169.0 54.8 1.9e-16 60.2 14.3 6.2 2 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95833.1 - 1.5e-10 40.6 0.2 0.0079 15.9 0.0 8.0 6 2 3 9 9 9 3 Leucine rich repeat Cyclophil_like2 PF18050.1 EAX95834.1 - 5.4e-19 68.2 0.0 7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like family TMEM154 PF15102.6 EAX95834.1 - 0.01 15.7 3.2 0.015 15.2 3.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 EAX95834.1 - 0.045 13.5 0.2 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 EAX95834.1 - 0.083 12.8 2.6 0.095 12.6 2.6 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EAX95834.1 - 0.092 13.0 1.1 0.17 12.2 1.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) PRIMA1 PF16101.5 EAX95834.1 - 0.1 12.7 2.5 0.14 12.2 2.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ETRAMP PF09716.10 EAX95834.1 - 0.43 10.7 2.9 0.44 10.7 3.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Syndecan PF01034.20 EAX95834.1 - 1 9.3 3.5 1.7 8.6 3.5 1.3 1 0 0 1 1 1 0 Syndecan domain SNF2_N PF00176.23 EAX95835.1 - 2.1e-56 191.2 0.5 3.7e-56 190.3 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX95835.1 - 1.5e-22 80.0 0.1 5.6e-22 78.2 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EAX95835.1 - 2.9e-15 55.9 1.2 1.4e-06 28.1 0.1 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 EAX95835.1 - 3.7e-14 52.3 0.5 7.9e-14 51.2 0.5 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EAX95835.1 - 3e-10 40.1 0.0 6.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus ResIII PF04851.15 EAX95835.1 - 1.7e-06 28.2 0.0 1.7e-06 28.2 0.0 3.5 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX95835.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Tudor-knot PF11717.8 EAX95835.1 - 6.1e-05 22.8 0.2 0.00016 21.5 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_14 PF13173.6 EAX95835.1 - 0.00043 20.3 0.8 0.0055 16.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain HDA2-3 PF11496.8 EAX95835.1 - 0.00064 19.0 2.4 0.00064 19.0 2.4 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 EAX95835.1 - 0.015 15.6 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EAX95836.1 - 2.2e-60 204.3 0.2 3.3e-60 203.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95836.1 - 3.1e-39 134.8 0.0 3.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95836.1 - 6.2e-07 29.0 0.0 8e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 EAX95836.1 - 3.2e-05 23.6 0.3 0.00056 19.6 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 EAX95836.1 - 5.2e-05 22.7 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX95836.1 - 6e-05 23.1 0.1 8.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX95836.1 - 0.0053 15.6 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ank_2 PF12796.7 EAX95837.1 - 1.5e-27 96.0 13.0 1.2e-10 41.8 0.2 5.4 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX95837.1 - 1e-19 70.2 4.8 1e-19 70.2 4.8 4.9 5 1 1 6 6 6 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX95837.1 - 5.2e-18 65.2 15.1 0.00028 21.4 0.1 7.5 3 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95837.1 - 2.3e-16 58.2 13.4 0.034 14.7 0.1 9.4 8 1 1 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 EAX95837.1 - 4.7e-15 55.5 8.0 3.9e-05 23.8 0.0 6.8 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX95837.1 - 1.1e-11 44.6 9.6 0.003 17.9 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeat PTSIIB_sorb PF03830.15 EAX95837.1 - 0.019 15.2 0.5 0.12 12.6 0.1 2.5 2 1 1 3 3 3 0 PTS system sorbose subfamily IIB component Arg_repressor PF01316.21 EAX95837.1 - 0.064 13.0 0.4 3.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain T3RM_EcoP15I_C PF18273.1 EAX95837.1 - 0.75 10.1 6.8 0.12 12.7 1.1 2.8 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain Fringe PF02434.16 EAX95838.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Fringe-like Pkinase PF00069.25 EAX95839.1 - 9.1e-06 25.2 0.3 1.6e-05 24.4 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAX95839.1 - 5e-05 22.8 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAX95839.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EAX95839.1 - 0.011 15.0 0.2 0.021 14.1 0.2 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 EAX95840.1 - 2.3e-26 92.2 2.4 6.6e-15 55.5 0.1 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95840.1 - 8e-22 77.3 4.4 2.1e-12 47.3 0.2 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95840.1 - 9.6e-16 57.6 0.7 5e-06 26.7 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95840.1 - 5.3e-14 51.0 5.3 0.00012 22.2 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAX95840.1 - 1.8e-12 47.1 4.4 0.0015 18.8 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat AAA_lid_10 PF17872.1 EAX95840.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA lid domain IBD PF10416.9 EAX95842.1 - 4.5e-43 146.3 0.1 6.3e-43 145.9 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD TTL PF03133.15 EAX95843.1 - 4.2e-73 246.0 0.4 6e-73 245.5 0.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX95843.1 - 3.5e-10 39.6 0.0 0.00022 20.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX95843.1 - 1.1e-06 28.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX95843.1 - 0.0068 16.5 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EAX95843.1 - 0.09 12.4 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EAX95843.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain TMP PF05017.14 EAX95847.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX95848.1 - 0.057 13.9 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX95849.1 - 1.8e-49 165.6 40.5 4.6e-31 106.7 13.4 3.7 3 1 1 4 4 4 2 Phage tail repeat like PH_TFIIH PF08567.11 EAX95849.1 - 0.5 10.7 5.8 21 5.5 0.3 3.5 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain GUN4_N PF16416.5 EAX95849.1 - 0.54 10.3 2.1 3.8 7.6 0.3 2.5 1 1 2 3 3 3 0 ARM-like repeat domain, GUN4-N terminal AviRa PF11599.8 EAX95849.1 - 0.82 9.1 4.0 1.2 8.6 0.4 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF1493 PF07377.12 EAX95850.1 - 0.022 15.2 0.6 0.045 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX95851.1 - 0.13 13.0 7.8 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX95851.1 - 4.3 7.3 8.2 4.7 7.2 8.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX95852.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP tRNA-synt_2b PF00587.25 EAX95853.1 - 1.4e-21 77.2 0.0 3.1e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAX95853.1 - 2.3e-18 66.1 0.0 3.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 EAX95853.1 - 5.4e-11 42.6 0.0 1.6e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF3719 PF12516.8 EAX95853.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Ank_4 PF13637.6 EAX95854.1 - 3.3e-68 225.2 11.0 4.3e-13 49.5 0.0 9.5 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX95854.1 - 5.1e-64 210.1 14.3 7.6e-08 32.5 0.1 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.7 EAX95854.1 - 9.9e-59 195.9 45.5 2.1e-16 60.2 4.9 6.6 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95854.1 - 3.2e-55 177.6 20.6 4.7e-06 26.5 0.1 11.7 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 EAX95854.1 - 3.8e-39 132.2 25.0 8.4e-10 38.7 0.2 7.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX95854.1 - 4.6e-38 129.0 4.6 4.6e-38 129.0 4.6 6.9 3 2 3 7 7 7 1 Domain of unknown function (DUF3447) DUF1610 PF07754.11 EAX95854.1 - 0.0012 18.7 7.7 39 4.3 0.1 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1610) DUF3130 PF11328.8 EAX95854.1 - 0.17 12.1 8.0 17 5.7 0.3 4.7 3 2 2 6 6 6 0 Protein of unknown function (DUF3130 ATPase PF06745.13 EAX95854.1 - 0.18 11.1 1.6 26 4.0 0.2 2.9 1 1 1 3 3 3 0 KaiC Amdase PF17645.1 EAX95854.1 - 0.36 10.4 2.6 12 5.4 0.1 3.9 1 1 4 5 5 5 0 Arylmalonate decarboxylase Peptidase_Mx PF15887.5 EAX95854.1 - 0.4 10.0 4.4 6.9 6.0 0.5 3.1 1 1 0 2 2 2 0 Putative zinc-binding metallo-peptidase SPK PF04435.18 EAX95855.1 - 0.0012 19.2 1.6 0.0014 19.0 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF545) NPA PF16469.5 EAX95855.1 - 0.009 16.6 1.5 0.011 16.3 1.5 1.3 1 1 0 1 1 1 1 Nematode polyprotein allergen ABA-1 SOGA PF11365.8 EAX95855.1 - 0.019 16.0 1.7 0.023 15.8 1.7 1.1 1 0 0 1 1 1 0 Protein SOGA YrzO PF14142.6 EAX95855.1 - 0.12 12.3 2.9 0.18 11.7 2.5 1.6 1 1 0 1 1 1 0 YrzO-like protein DUF4615 PF15393.6 EAX95856.1 - 0.0014 19.2 17.3 0.0014 19.2 17.3 4.2 3 2 1 4 4 4 1 Domain of unknown function (DUF4615) SecM PF06558.12 EAX95856.1 - 0.15 12.1 0.4 5.6 7.1 0.1 3.2 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) Herpes_UL17 PF04559.12 EAX95856.1 - 3.8 6.2 7.1 29 3.3 6.9 2.1 1 1 0 1 1 1 0 Herpesvirus UL17 protein JAB PF01398.21 EAX95857.1 - 0.00023 21.1 0.0 0.00075 19.5 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UN_NPL4 PF11543.8 EAX95858.1 - 0.12 12.9 4.2 4.6 7.8 0.2 3.2 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 PX PF00787.24 EAX95859.1 - 5.5e-06 26.3 0.2 6.8e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 PX domain NIF PF03031.18 EAX95860.1 - 6.9e-50 168.9 0.0 9.8e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase pP_pnuc_1 PF18165.1 EAX95860.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease Zip PF02535.22 EAX95861.1 - 7.5e-26 91.1 12.9 1.3e-18 67.3 2.2 2.1 1 1 0 2 2 2 2 ZIP Zinc transporter Cthe_2159 PF14262.6 EAX95861.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 2 0 0 2 2 2 0 Carbohydrate-binding domain-containing protein Cthe_2159 MnhB PF04039.13 EAX95861.1 - 0.29 11.5 9.4 1.5 9.1 1.2 3.3 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF1129 PF06570.11 EAX95861.1 - 0.36 10.3 2.9 0.26 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1978 PF09321.10 EAX95862.1 - 0.0045 16.3 2.3 0.0045 16.3 2.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1978) DUF948 PF06103.11 EAX95862.1 - 0.52 10.6 3.0 3.9 7.8 0.2 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EAX95862.1 - 1.3 9.1 4.9 1.5 8.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EAX95862.1 - 5.4 7.4 9.8 1.2 9.5 2.5 2.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UCH PF00443.29 EAX95863.1 - 4.6e-21 75.5 0.0 6.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX95863.1 - 1.1e-07 31.8 0.2 6.9e-07 29.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 EAX95863.1 - 0.041 13.7 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain TPR_2 PF07719.17 EAX95864.1 - 7.2e-24 81.9 14.7 0.0025 17.8 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAX95864.1 - 2.9e-23 82.2 20.3 4.3e-05 23.9 0.1 6.3 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EAX95864.1 - 1.4e-15 57.2 16.2 2.8e-05 24.2 0.4 6.8 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAX95864.1 - 3e-15 55.3 17.7 0.00018 21.2 0.0 7.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAX95864.1 - 1.9e-14 53.1 16.3 3e-05 23.6 0.0 8.4 7 2 2 9 9 9 3 TPR repeat TPR_12 PF13424.6 EAX95864.1 - 3.6e-13 49.6 12.9 0.0011 19.2 0.6 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAX95864.1 - 1.7e-11 43.9 18.0 0.0042 17.8 0.1 8.3 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX95864.1 - 8.3e-11 42.4 14.5 0.11 13.2 0.0 6.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAX95864.1 - 6e-09 35.4 10.4 0.0055 16.8 0.0 7.2 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAX95864.1 - 3.5e-08 33.3 6.7 3.9 8.1 0.0 8.2 8 2 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX95864.1 - 1.2e-07 31.9 13.3 0.00058 20.0 1.8 4.3 3 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EAX95864.1 - 2.1e-06 27.7 9.4 0.0013 18.7 1.2 4.5 4 1 2 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EAX95864.1 - 5.6e-06 25.6 6.8 0.044 12.7 0.0 4.3 2 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EAX95864.1 - 0.00046 20.5 10.7 0.081 13.3 0.4 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAX95864.1 - 0.00077 19.1 2.7 5.2 6.7 0.0 4.0 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 EAX95864.1 - 0.00091 18.5 4.5 0.036 13.3 0.1 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 EAX95864.1 - 0.0013 19.2 5.5 0.11 12.9 0.0 4.4 3 1 3 6 6 6 1 Bacterial transcriptional activator domain Coatomer_E PF04733.14 EAX95864.1 - 0.0021 17.5 3.3 0.0052 16.2 0.1 2.8 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_7 PF13176.6 EAX95864.1 - 0.0023 17.9 4.9 21 5.5 0.1 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EAX95864.1 - 0.0071 16.8 1.9 4.1 7.8 0.1 3.2 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_10 PF13374.6 EAX95864.1 - 0.014 15.3 3.6 47 4.0 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAX95864.1 - 0.016 15.8 8.0 51 4.8 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAX95864.1 - 0.019 15.6 2.3 31 5.6 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAX95864.1 - 0.022 14.2 1.1 2.1 7.9 0.0 3.8 4 0 0 4 4 4 0 SHNi-TPR MIT PF04212.18 EAX95864.1 - 0.055 13.5 5.3 0.21 11.7 0.4 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 EAX95864.1 - 0.099 12.4 0.3 7.5 6.3 0.0 3.3 4 0 0 4 4 2 0 Domain of unknown function (DUF5113) T3SS_needle_F PF09392.10 EAX95864.1 - 0.11 12.7 1.8 2.4 8.4 0.0 2.9 3 0 0 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF TPR_21 PF09976.9 EAX95864.1 - 0.39 10.4 12.1 2.8 7.6 0.6 4.1 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain HSCB_C PF07743.13 EAX95864.1 - 1.7 9.2 7.0 3.8 8.1 0.0 3.4 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain YfdX PF10938.8 EAX95864.1 - 6.7 6.6 12.6 9.6 6.1 0.9 4.0 4 2 0 4 4 4 0 YfdX protein CRR7 PF12095.8 EAX95865.1 - 0.02 15.3 1.6 0.026 15.0 1.6 1.2 1 1 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Synaptobrevin PF00957.21 EAX95865.1 - 0.078 12.8 4.8 0.12 12.1 4.8 1.4 1 0 0 1 1 1 0 Synaptobrevin HMA PF00403.26 EAX95865.1 - 0.1 13.1 0.4 0.1 13.1 0.4 1.5 2 0 0 2 2 2 0 Heavy-metal-associated domain SapB_2 PF03489.17 EAX95866.1 - 0.093 12.9 2.9 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 2 Pkinase PF00069.25 EAX95867.1 - 4.1e-74 249.3 0.0 1e-72 244.7 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX95867.1 - 3e-42 144.7 0.0 4.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX95867.1 - 1.6e-06 27.6 0.0 7.8e-06 25.4 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EAX95867.1 - 5.5e-05 23.2 0.2 0.0016 18.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX95867.1 - 0.0039 16.2 0.1 0.0066 15.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EAX95867.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EAX95867.1 - 0.078 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX95867.1 - 0.085 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nipped-B_C PF12830.7 EAX95868.1 - 0.00015 21.7 1.3 0.022 14.7 0.2 2.9 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 EAX95868.1 - 0.11 12.7 0.0 1.9 8.7 0.0 3.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 EAX95868.1 - 0.34 11.4 2.4 11 6.5 0.0 4.2 4 0 0 4 4 4 0 Telomere length regulation protein LRR_5 PF13306.6 EAX95869.1 - 1.5e-95 315.9 73.4 4.2e-26 91.4 15.3 7.5 2 2 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95869.1 - 1.8e-23 82.1 4.9 0.0064 16.2 0.0 9.3 6 3 3 10 10 10 7 Leucine rich repeat DUF2205 PF10224.9 EAX95870.1 - 0.055 13.5 0.3 0.074 13.1 0.3 1.3 1 0 0 1 1 1 0 Short coiled-coil protein Myb_DNA-binding PF00249.31 EAX95871.1 - 2e-05 24.7 1.5 0.013 15.6 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain UBA PF00627.31 EAX95871.1 - 0.0041 17.0 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 EAX95871.1 - 0.0085 15.8 0.0 0.0085 15.8 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin family UBA_6 PF18039.1 EAX95871.1 - 0.025 14.5 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain NifU PF01106.17 EAX95873.1 - 2.8e-20 72.2 0.4 3.5e-20 71.9 0.4 1.1 1 0 0 1 1 1 1 NifU-like domain PX PF00787.24 EAX95874.1 - 1.1e-10 41.4 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 PX domain DUF1842 PF08896.10 EAX95874.1 - 0.041 14.1 0.0 0.076 13.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1842) LRR_5 PF13306.6 EAX95875.1 - 8.5e-99 326.4 61.4 1.8e-27 95.8 8.2 6.4 2 2 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95875.1 - 1.5e-32 111.1 2.7 5.1e-07 29.4 0.1 9.1 6 3 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EAX95875.1 - 0.001 19.4 22.6 0.32 11.5 0.8 7.2 5 2 4 9 9 9 4 Leucine Rich repeats (2 copies) zf-Tim10_DDP PF02953.15 EAX95875.1 - 0.39 10.4 14.2 2.8 7.7 0.1 4.6 4 1 2 6 6 6 0 Tim10/DDP family zinc finger LRR_1 PF00560.33 EAX95875.1 - 4 8.4 9.1 14 6.7 0.2 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat Beach PF02138.18 EAX95876.1 - 2.2e-109 365.1 0.1 2.2e-109 365.1 0.1 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 EAX95876.1 - 3.7e-15 55.9 0.5 3.7e-15 55.9 0.5 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAX95876.1 - 1e-10 41.6 1.8 5e-10 39.4 1.8 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 EAX95876.1 - 4e-07 29.6 3.1 4e-07 29.6 3.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) DUF3700 PF12481.8 EAX95876.1 - 0.004 16.6 0.2 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 Aluminium induced protein Peptidase_M1 PF01433.20 EAX95877.1 - 5e-56 189.7 0.1 1.1e-55 188.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EAX95877.1 - 2.5e-31 109.3 0.6 6.1e-31 108.1 0.6 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 EAX95877.1 - 1.5e-24 87.1 0.0 2.1e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Flavoprotein PF02441.19 EAX95877.1 - 0.025 14.3 0.7 0.05 13.4 0.7 1.4 1 0 0 1 1 1 0 Flavoprotein WSD PF15613.6 EAX95877.1 - 0.13 12.8 0.5 4.5 7.8 0.0 3.2 2 2 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF3361 PF11841.8 EAX95879.1 - 0.088 12.7 3.6 0.17 11.8 0.3 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF3361) PAS_9 PF13426.7 EAX95882.1 - 1.4e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 EAX95882.1 - 0.00042 20.4 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX95882.1 - 0.089 13.1 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 PAS fold Tetraspanin PF00335.20 EAX95884.1 - 8.2e-22 78.0 21.4 1e-21 77.7 21.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Picorna_P3A PF06363.11 EAX95884.1 - 0.056 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Picornaviridae P3A protein Anoctamin PF04547.12 EAX95884.1 - 0.059 12.2 8.1 0.01 14.7 4.2 1.6 1 1 1 2 2 2 0 Calcium-activated chloride channel Ribophorin_II PF05817.14 EAX95884.1 - 0.3 9.6 7.5 0.53 8.8 7.5 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Phtf-FEM1B_bdg PF12129.8 EAX95884.1 - 3.8 7.3 8.2 6.2 6.6 6.1 2.1 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor LRRC37AB_C PF14914.6 EAX95884.1 - 5.2 7.0 8.0 14 5.6 0.2 2.4 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Trypan_PARP PF05887.11 EAX95886.1 - 0.076 13.0 13.2 0.078 13.0 13.2 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX95886.1 - 4.5 7.7 8.2 5.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX95887.1 - 0.017 15.2 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX95888.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3839 PF12943.7 EAX95889.1 - 1.8e-154 512.2 12.8 2.2e-154 511.9 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX95889.1 - 0.029 14.8 0.7 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) KELK PF15796.5 EAX95889.1 - 4.6 7.8 7.3 1.9 9.0 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Gly-zipper_Omp PF13488.6 EAX95890.1 - 0.0098 15.9 9.0 0.0098 15.9 9.0 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX95890.1 - 0.32 11.3 4.8 0.49 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX95890.1 - 1.3 9.2 5.8 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif 60KD_IMP PF02096.20 EAX95892.1 - 0.36 10.7 2.9 0.42 10.5 1.4 1.8 1 1 1 2 2 2 0 60Kd inner membrane protein HATPase_c PF02518.26 EAX95893.1 - 1.2e-24 87.0 0.8 2.8e-24 85.8 0.8 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAX95893.1 - 1.7e-11 44.2 0.9 5.6e-11 42.6 0.5 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EAX95893.1 - 3.1e-10 39.9 0.3 8.5e-10 38.5 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Orf78 PF06024.12 EAX95893.1 - 0.013 15.8 1.2 0.05 13.9 1.2 2.0 1 0 0 1 1 1 0 Orf78 (ac78) Prim-Pol PF09250.11 EAX95894.1 - 0.0069 16.8 0.0 0.0098 16.3 0.0 1.2 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal DUF705 PF05152.12 EAX95894.1 - 0.019 14.4 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF2097 PF09870.9 EAX95894.1 - 0.075 13.2 0.6 0.63 10.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) SYF2 PF08231.12 EAX95895.1 - 7.5e-14 52.4 16.5 1.2e-13 51.8 16.5 1.4 1 1 0 1 1 1 1 SYF2 splicing factor IL31 PF15209.6 EAX95895.1 - 0.032 14.0 0.6 0.098 12.4 0.2 1.9 1 1 1 2 2 2 0 Interleukin 31 Bromodomain PF00439.25 EAX95897.1 - 2.5e-21 75.5 0.1 4.5e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Bromodomain DUF4945 PF16303.5 EAX95897.1 - 0.059 13.3 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4945) V-ATPase_G PF03179.15 EAX95898.1 - 6.8e-14 52.3 18.5 7.2e-14 52.2 18.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Syntaxin-6_N PF09177.11 EAX95898.1 - 0.0022 18.5 5.7 0.0026 18.3 5.7 1.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Activator-TraM PF11657.8 EAX95898.1 - 0.0032 17.3 10.1 0.0038 17.1 10.1 1.0 1 0 0 1 1 1 1 Transcriptional activator TraM RRF PF01765.19 EAX95898.1 - 0.0036 17.3 16.2 0.0053 16.7 16.1 1.3 1 1 0 1 1 1 1 Ribosome recycling factor Apolipoprotein PF01442.18 EAX95898.1 - 0.008 16.1 9.7 0.012 15.5 9.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Nop25 PF09805.9 EAX95898.1 - 0.0081 16.6 14.2 0.0096 16.4 14.2 1.0 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Mitofilin PF09731.9 EAX95898.1 - 0.0086 15.0 16.6 0.0099 14.8 16.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein GBP_C PF02841.14 EAX95898.1 - 0.013 14.9 16.7 0.016 14.6 16.7 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Borrelia_P83 PF05262.11 EAX95898.1 - 0.014 13.9 15.1 0.015 13.8 15.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein V-ATPase_G_2 PF16999.5 EAX95898.1 - 0.016 15.6 19.5 0.027 14.9 19.5 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EAX95898.1 - 0.021 14.9 21.9 0.066 13.3 21.9 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HAUS-augmin3 PF14932.6 EAX95898.1 - 0.025 14.2 7.7 0.029 13.9 7.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4736 PF15883.5 EAX95898.1 - 0.026 14.3 5.6 0.033 13.9 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Phasin PF05597.11 EAX95898.1 - 0.026 14.5 7.1 0.033 14.2 7.1 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Peptidase_S30 PF01577.16 EAX95898.1 - 0.027 14.1 8.3 0.031 13.9 8.3 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease DUF4735 PF15882.5 EAX95898.1 - 0.032 13.7 2.8 0.042 13.3 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DUF883 PF05957.13 EAX95898.1 - 0.084 13.5 10.2 0.62 10.7 9.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PIN_8 PF18476.1 EAX95898.1 - 0.12 12.2 9.5 0.14 12.0 9.5 1.0 1 0 0 1 1 1 0 PIN like domain DUF2203 PF09969.9 EAX95898.1 - 0.21 12.3 6.2 0.27 11.9 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ZYG-11_interact PF05884.12 EAX95898.1 - 0.24 10.8 3.5 0.28 10.5 3.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 FPRL1_inhibitor PF16104.5 EAX95898.1 - 0.3 11.3 8.9 1.5 9.0 5.7 2.1 1 1 1 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein Prismane PF03063.20 EAX95898.1 - 0.38 9.4 5.7 0.4 9.3 5.7 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family FeoB_Cyto PF17910.1 EAX95898.1 - 0.38 11.3 13.8 1.1 9.8 2.2 2.1 1 1 1 2 2 2 0 FeoB cytosolic helical domain DUF3552 PF12072.8 EAX95898.1 - 1.1 8.7 23.7 3.3 7.1 22.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Aldedh PF00171.22 EAX95898.1 - 1.1 7.7 6.3 1.2 7.6 6.3 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family HAUS6_N PF14661.6 EAX95898.1 - 1.3 8.6 9.6 1.6 8.3 9.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIVA PF05103.13 EAX95898.1 - 1.4 9.0 18.2 1.5 8.9 16.1 1.8 1 1 1 2 2 2 0 DivIVA protein WPP PF13943.6 EAX95898.1 - 1.7 9.1 6.5 1.1 9.7 4.7 1.5 1 1 1 2 2 2 0 WPP domain Pinin_SDK_memA PF04696.13 EAX95898.1 - 1.7 8.7 16.4 2.2 8.3 16.4 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region F-protein PF00469.20 EAX95898.1 - 1.9 8.1 5.8 2.2 7.8 5.8 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF1943 PF09172.11 EAX95898.1 - 2.4 7.3 5.5 2.7 7.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Atg14 PF10186.9 EAX95898.1 - 2.8 6.9 10.3 3 6.8 10.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EAX95898.1 - 3.4 6.8 7.8 3.8 6.7 7.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein RNase_J_C PF17770.1 EAX95898.1 - 3.7 8.7 8.9 5.3 8.2 7.3 2.0 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain Mt_ATP-synt_D PF05873.12 EAX95898.1 - 5.2 6.9 13.2 2.6 7.9 8.7 1.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) PDCD2_C PF04194.13 EAX95898.1 - 5.6 7.0 8.8 6.7 6.7 8.8 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Halogen_Hydrol PF10112.9 EAX95898.1 - 6.9 6.7 10.9 54 3.7 10.9 1.9 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4337 PF14235.6 EAX95898.1 - 7.9 6.6 10.7 9.4 6.3 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SNF5 PF04855.12 EAX95899.1 - 1.3e-15 57.9 2.9 2.4e-10 40.6 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Bromodomain PF00439.25 EAX95900.1 - 6.5e-19 67.8 2.9 9.5e-19 67.3 2.1 1.7 2 0 0 2 2 2 1 Bromodomain DENN PF02141.21 EAX95901.1 - 0.0015 18.6 0.1 0.004 17.1 0.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain T6SS_VipA PF05591.12 EAX95901.1 - 0.034 13.9 0.5 0.066 13.0 0.1 1.6 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Arm_2 PF04826.13 EAX95902.1 - 4.8e-06 26.2 3.0 0.02 14.3 0.4 2.4 2 1 0 2 2 2 2 Armadillo-like Katanin_con80 PF13925.6 EAX95902.1 - 0.013 15.5 0.9 12 5.9 0.0 3.5 2 1 1 3 3 3 0 con80 domain of Katanin GFP PF01353.22 EAX95902.1 - 0.035 13.6 0.2 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 Green fluorescent protein RPAP3_C PF13877.6 EAX95902.1 - 0.19 12.3 1.8 1.4 9.5 0.0 2.7 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 RE_CfrBI PF09516.10 EAX95903.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease Propeptide_C1 PF08127.13 EAX95904.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide Metallophos PF00149.28 EAX95905.1 - 1.3e-37 130.3 0.2 1.6e-37 130.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX95905.1 - 4.2e-10 39.9 0.4 7e-10 39.2 0.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX95905.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MatE PF01554.18 EAX95906.1 - 5.3e-18 65.2 21.1 3.9e-12 46.1 9.5 2.6 2 0 0 2 2 2 2 MatE Pkinase PF00069.25 EAX95908.1 - 5e-05 22.8 0.1 8.1e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain PRP21_like_P PF12230.8 EAX95908.1 - 0.0051 16.7 0.2 0.0088 15.9 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein RNF220 PF15926.5 EAX95908.1 - 0.022 14.4 0.7 0.039 13.6 0.3 1.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf_UBZ PF18439.1 EAX95908.1 - 0.17 11.5 1.0 0.3 10.7 1.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 EAX95911.1 - 0.005 16.7 0.2 0.0091 15.9 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein RNF220 PF15926.5 EAX95911.1 - 0.019 14.6 0.3 0.041 13.5 0.3 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 RNase_J_C PF17770.1 EAX95911.1 - 0.12 13.5 0.1 0.62 11.1 0.1 2.3 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain zf_UBZ PF18439.1 EAX95911.1 - 0.18 11.5 1.0 0.31 10.7 1.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger TMP PF05017.14 EAX95912.1 - 0.035 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat TMP PF05017.14 EAX95915.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX95916.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-binding PF00249.31 EAX95917.1 - 9e-31 105.8 1.4 1.6e-15 57.0 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95917.1 - 1.2e-24 86.3 5.3 2.7e-16 59.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX95917.1 - 4.3e-06 26.7 0.1 0.0011 19.0 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX95917.1 - 8.9e-05 22.3 0.5 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX95917.1 - 0.035 14.5 4.0 0.67 10.4 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX95917.1 - 0.074 13.2 1.3 4.8 7.4 0.0 3.0 2 1 0 2 2 2 0 Rap1 Myb domain DUF722 PF05263.11 EAX95917.1 - 0.093 13.0 0.0 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF722) WD40 PF00400.32 EAX95918.1 - 0.3 12.0 1.8 1.9 9.5 1.4 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat TMEM154 PF15102.6 EAX95919.1 - 3.7e-05 23.7 3.4 3.7e-05 23.7 3.4 3.4 4 0 0 4 4 4 1 TMEM154 protein family Glycophorin_A PF01102.18 EAX95919.1 - 0.012 15.8 2.0 0.012 15.8 2.0 2.1 2 0 0 2 2 2 0 Glycophorin A DUF1180 PF06679.12 EAX95919.1 - 0.021 15.3 2.5 0.071 13.5 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5385 PF17359.2 EAX95919.1 - 0.034 13.7 0.1 0.054 13.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Mid2 PF04478.12 EAX95919.1 - 0.04 13.8 3.4 0.13 12.1 3.4 1.9 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 EAX95919.1 - 0.056 13.5 1.5 0.12 12.4 1.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 EAX95919.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 EAX95919.1 - 0.089 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Pkinase_Tyr PF07714.17 EAX95920.1 - 6.4e-60 202.6 0.2 1.9e-58 197.8 0.0 2.7 2 2 2 4 4 4 1 Protein tyrosine kinase Pkinase PF00069.25 EAX95920.1 - 5.5e-56 189.9 0.0 1.2e-55 188.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAX95920.1 - 1e-06 27.9 0.0 2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Csm2_III-A PF03750.13 EAX95920.1 - 0.063 14.1 2.3 14 6.6 0.1 2.5 2 0 0 2 2 2 0 Csm2 Type III-A Kdo PF06293.14 EAX95920.1 - 0.076 12.4 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family vATP-synt_E PF01991.18 EAX95921.1 - 1.4e-34 119.3 8.2 1.6e-34 119.1 8.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Gtr1_RagA PF04670.12 EAX95921.1 - 0.028 13.8 0.8 0.077 12.3 0.1 1.7 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region Cro PF09048.10 EAX95921.1 - 0.041 13.9 0.4 0.15 12.1 0.1 2.2 1 1 0 1 1 1 0 Cro Tet_JBP PF12851.7 EAX95921.1 - 0.097 12.0 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily ATP-synt_B PF00430.18 EAX95921.1 - 0.75 9.9 12.6 7 6.7 0.4 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HEAT PF02985.22 EAX95922.1 - 9e-07 28.6 1.3 0.63 10.5 0.1 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EAX95922.1 - 2.7e-06 27.7 0.0 0.26 11.7 0.0 4.6 2 2 5 7 7 7 4 HEAT repeats GST_C_3 PF14497.6 EAX95922.1 - 0.079 13.2 0.6 0.87 9.8 0.1 2.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RIH_assoc PF08454.11 EAX95922.1 - 2.3 8.1 7.2 1 9.2 2.2 2.8 2 1 0 2 2 2 0 RyR and IP3R Homology associated Glyco_hydro_1 PF00232.18 EAX95923.1 - 1.4e-75 254.5 1.6 4.1e-75 252.9 1.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 EAX95923.1 - 0.00011 21.5 0.9 0.0092 15.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EAX95923.1 - 0.00078 18.9 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase Aldo_ket_red PF00248.21 EAX95923.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.5 1 1 0 1 1 1 0 Aldo/keto reductase family Ank_4 PF13637.6 EAX95924.1 - 5e-20 71.6 0.2 1.5e-11 44.6 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX95924.1 - 1.2e-17 63.7 1.3 1.4e-09 38.0 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95924.1 - 7e-17 61.8 0.1 9e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX95924.1 - 1.7e-14 52.5 0.2 6.4e-05 23.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX95924.1 - 1.7e-13 50.3 0.3 7.8e-06 26.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF2362 PF10154.9 EAX95924.1 - 0.07 12.1 0.1 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Tubulin PF00091.25 EAX95926.1 - 5.9e-68 229.0 0.0 8.4e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX95926.1 - 2.4e-50 169.9 0.0 3.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAX95926.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAX95926.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3447 PF11929.8 EAX95927.1 - 2.7e-38 129.8 5.3 2.7e-38 129.8 5.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX95927.1 - 3.3e-16 59.7 0.5 2e-09 37.9 0.1 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95927.1 - 4.6e-14 52.6 2.3 0.00016 22.2 0.0 4.9 3 3 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95927.1 - 1.7e-10 40.2 2.7 0.059 13.9 0.0 6.7 6 1 1 7 7 7 2 Ankyrin repeat Ank PF00023.30 EAX95927.1 - 1.6e-07 31.5 0.3 0.77 10.3 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX95927.1 - 0.00032 20.9 0.1 0.12 12.7 0.0 4.0 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX95928.1 - 5.6e-32 110.2 0.0 6.1e-19 68.4 0.0 3.1 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95928.1 - 1.4e-24 86.1 0.0 5.2e-09 36.5 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95928.1 - 3.3e-21 73.1 0.0 0.0082 16.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX95928.1 - 5.9e-20 71.1 0.0 5.3e-07 29.8 0.0 4.8 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX95928.1 - 4.9e-19 67.9 0.0 0.00021 21.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat MscS_porin PF12795.7 EAX95928.1 - 5.5e-05 22.8 24.4 8.7e-05 22.2 24.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF812 PF05667.11 EAX95928.1 - 0.00012 21.1 21.4 0.00016 20.7 21.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ADIP PF11559.8 EAX95928.1 - 0.00021 21.4 18.2 0.00021 21.4 18.2 2.7 2 1 1 3 3 2 1 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 EAX95928.1 - 0.00059 20.1 17.9 0.00059 20.1 17.9 1.6 2 0 0 2 2 1 1 JNK_SAPK-associated protein-1 BAR_3 PF16746.5 EAX95928.1 - 0.0015 18.3 10.1 0.0015 18.3 10.1 2.4 1 1 0 2 2 2 1 BAR domain of APPL family Fez1 PF06818.15 EAX95928.1 - 0.002 18.6 14.1 0.0031 18.0 14.1 1.3 1 0 0 1 1 1 1 Fez1 APG6_N PF17675.1 EAX95928.1 - 0.0027 18.2 21.8 0.011 16.3 21.4 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region ERM PF00769.19 EAX95928.1 - 0.0027 17.5 15.7 0.0043 16.9 15.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EAX95928.1 - 0.003 17.6 15.9 0.0059 16.6 15.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EAX95928.1 - 0.0043 16.0 14.2 0.0057 15.6 14.2 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.6 EAX95928.1 - 0.0058 16.4 19.9 0.012 15.4 19.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3450 PF11932.8 EAX95928.1 - 0.0064 15.8 23.2 0.011 15.0 23.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF948 PF06103.11 EAX95928.1 - 0.0095 16.2 5.3 0.0095 16.2 5.3 2.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 EAX95928.1 - 0.011 14.7 24.7 0.0084 15.0 23.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAX95928.1 - 0.016 12.7 21.5 0.023 12.2 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Allexi_40kDa PF05549.11 EAX95928.1 - 0.024 14.1 10.5 0.038 13.5 10.5 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein FAM76 PF16046.5 EAX95928.1 - 0.041 13.2 17.8 0.063 12.6 17.8 1.4 1 0 0 1 1 1 0 FAM76 protein FPP PF05911.11 EAX95928.1 - 0.044 12.0 22.5 0.054 11.7 22.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 EAX95928.1 - 0.057 13.0 13.5 0.077 12.6 13.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EAX95928.1 - 0.063 11.2 15.6 0.082 10.8 15.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAP1_N PF04849.13 EAX95928.1 - 0.069 12.3 23.4 0.011 14.9 18.0 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region MCPsignal PF00015.21 EAX95928.1 - 0.08 12.7 14.1 0.044 13.6 11.1 2.0 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_HK97_TLTM PF06120.11 EAX95928.1 - 0.095 11.9 22.4 0.13 11.4 22.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF1664 PF07889.12 EAX95928.1 - 0.12 12.4 15.7 0.12 12.4 13.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EAX95928.1 - 0.12 12.4 15.5 0.39 10.7 15.5 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.20 EAX95928.1 - 0.14 11.5 17.9 0.23 10.8 17.9 1.2 1 0 0 1 1 1 0 Tropomyosin Atg14 PF10186.9 EAX95928.1 - 0.24 10.5 18.2 0.42 9.7 18.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 EAX95928.1 - 0.29 11.6 12.2 3.2 8.2 2.8 3.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HBM PF16591.5 EAX95928.1 - 0.48 9.8 19.8 0.79 9.1 19.8 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain Laminin_II PF06009.12 EAX95928.1 - 0.5 10.4 18.7 0.69 9.9 17.2 2.0 1 1 0 1 1 1 0 Laminin Domain II Sec34 PF04136.15 EAX95928.1 - 0.55 10.1 24.3 0.1 12.5 6.7 2.6 1 1 1 2 2 2 0 Sec34-like family DUF4200 PF13863.6 EAX95928.1 - 0.78 10.2 28.7 0.28 11.6 12.5 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) SpecificRecomb PF10136.9 EAX95928.1 - 0.81 7.9 6.3 1.1 7.4 6.3 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF4164 PF13747.6 EAX95928.1 - 0.93 9.8 6.9 1.5 9.1 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4407 PF14362.6 EAX95928.1 - 1 8.7 14.8 1.5 8.1 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 EAX95928.1 - 1.1 9.4 14.7 0.11 12.6 8.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.7 EAX95928.1 - 1.2 9.3 19.4 2.4 8.3 19.4 1.4 1 0 0 1 1 1 0 Tropomyosin like Tweety PF04906.13 EAX95928.1 - 1.3 7.6 11.7 0.79 8.3 9.0 1.9 1 1 0 2 2 2 0 Tweety Phage_GPO PF05929.11 EAX95928.1 - 1.3 8.6 22.5 6.5 6.3 21.5 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SOGA PF11365.8 EAX95928.1 - 1.7 9.9 12.2 0.23 12.6 4.7 2.7 1 1 1 2 2 2 0 Protein SOGA Golgin_A5 PF09787.9 EAX95928.1 - 1.7 8.1 25.4 3.9 6.8 25.3 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 EAX95928.1 - 1.9 7.6 22.4 1.5 7.9 20.4 1.8 1 1 1 2 2 2 0 TMPIT-like protein Spc24 PF08286.11 EAX95928.1 - 2 8.7 26.7 0.54 10.5 8.5 2.8 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 EAX95928.1 - 3 6.7 20.8 4.9 6.0 20.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein PRKG1_interact PF15898.5 EAX95928.1 - 3.1 8.7 22.4 0.65 10.9 10.6 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 EAX95928.1 - 3.4 8.1 20.8 9.8 6.6 19.9 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Flagellin_N PF00669.20 EAX95928.1 - 3.5 7.7 19.7 3.7 7.7 18.2 1.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Occludin_ELL PF07303.13 EAX95928.1 - 3.5 8.4 21.4 4.5 8.1 4.9 3.0 1 1 1 2 2 2 0 Occludin homology domain UPF0242 PF06785.11 EAX95928.1 - 4.9 7.2 33.0 7.2 6.7 28.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EAX95928.1 - 5.3 7.7 23.4 2.1 9.0 7.4 3.3 1 1 1 3 3 3 0 Initiation control protein YabA LPP PF04728.13 EAX95928.1 - 5.5 7.5 17.1 2.5 8.6 3.6 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper T4SS PF07996.11 EAX95928.1 - 5.7 7.3 30.9 70 3.7 15.8 2.8 1 1 1 2 2 2 0 Type IV secretion system proteins Seryl_tRNA_N PF02403.22 EAX95928.1 - 5.7 7.2 23.2 1.5 9.1 9.5 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DHR10 PF18595.1 EAX95928.1 - 5.7 7.0 24.3 11 6.1 13.4 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain PI_PP_I PF18363.1 EAX95928.1 - 6.7 7.0 15.4 61 3.9 14.2 2.8 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain BRE1 PF08647.11 EAX95928.1 - 7.9 6.6 32.9 0.043 13.9 16.2 2.7 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase ALMT PF11744.8 EAX95928.1 - 9 5.0 14.2 12 4.6 14.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Metallophos PF00149.28 EAX95929.1 - 9e-30 104.7 0.3 1.2e-29 104.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX95929.1 - 0.0033 17.6 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TGT PF01702.18 EAX95930.1 - 7.8e-38 130.5 0.1 2.8e-35 122.1 0.2 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase FAM165 PF14981.6 EAX95931.1 - 0.12 12.2 0.4 0.32 10.8 0.4 1.7 1 0 0 1 1 1 0 FAM165 family DUF846 PF05832.12 EAX95934.1 - 0.05 13.7 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Meiosis_expr PF15163.6 EAX95936.1 - 0.027 15.1 1.2 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed Tho2 PF11262.8 EAX95936.1 - 0.067 12.4 3.3 0.076 12.2 3.3 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PHP_C PF13263.6 EAX95936.1 - 0.15 11.8 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX95936.1 - 3.2 7.7 10.6 0.14 12.0 2.8 2.8 4 1 0 4 4 4 0 Spo12 family DUF1796 PF08795.10 EAX95937.1 - 0.096 12.6 0.0 15 5.5 0.1 2.1 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) SARAF PF06682.12 EAX95938.1 - 0.0033 17.1 1.7 0.0033 17.1 1.7 3.3 2 1 1 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Dexa_ind PF15198.6 EAX95938.1 - 0.0099 16.0 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 1 Dexamethasone-induced TMIE PF16038.5 EAX95938.1 - 0.3 11.0 1.8 0.88 9.5 1.8 1.7 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 EAX95938.1 - 7.7 7.5 6.7 88 4.1 3.8 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Symplekin_C PF12295.8 EAX95940.1 - 0.012 15.7 0.8 0.02 15.0 0.8 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal LRR_6 PF13516.6 EAX95941.1 - 1e-09 37.6 10.2 1.2e-05 25.0 0.0 5.6 6 0 0 6 6 6 3 Leucine Rich repeat Ank_2 PF12796.7 EAX95942.1 - 1.5e-69 230.6 12.6 1.3e-21 77.0 0.6 4.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX95942.1 - 1.7e-44 149.6 2.3 9.9e-11 42.0 0.0 6.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX95942.1 - 1.4e-39 132.8 0.1 9.4e-06 25.9 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX95942.1 - 1.5e-38 126.4 0.2 4e-05 23.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX95942.1 - 6.9e-34 115.5 2.5 3.3e-06 27.3 0.0 6.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) CCDC-167 PF15188.6 EAX95942.1 - 0.0016 18.7 4.3 0.0041 17.4 4.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 HAP1_N PF04849.13 EAX95942.1 - 0.006 15.8 2.1 0.009 15.3 2.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF812 PF05667.11 EAX95942.1 - 0.0097 14.8 2.9 0.014 14.3 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 EAX95942.1 - 0.041 13.9 4.8 0.07 13.2 4.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 EAX95942.1 - 0.045 13.4 2.4 0.08 12.5 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 EAX95942.1 - 0.052 13.5 10.3 0.094 12.7 10.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 EAX95942.1 - 0.072 13.3 4.3 0.13 12.5 4.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 EAX95942.1 - 0.081 11.8 2.4 0.12 11.2 2.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TssO PF17561.2 EAX95942.1 - 0.098 12.8 10.7 0.53 10.4 2.8 2.3 1 1 1 2 2 2 0 Type VI secretion system, TssO HopJ PF08888.11 EAX95942.1 - 0.41 10.9 3.5 19 5.6 0.7 2.7 3 0 0 3 3 2 0 HopJ type III effector protein YabA PF06156.13 EAX95942.1 - 0.43 11.2 6.3 1.1 10.0 6.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 EAX95942.1 - 3 8.1 6.7 0.57 10.5 2.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper F5_F8_type_C PF00754.25 EAX95943.1 - 0.00027 21.0 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain STT3 PF02516.14 EAX95944.1 - 9e-64 216.2 28.0 1.6e-63 215.3 28.0 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit E2F_TDP PF02319.20 EAX95945.1 - 1.4e-18 66.7 0.1 1.6e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain PH PF00169.29 EAX95946.1 - 8.5e-15 55.2 0.5 2.7e-14 53.6 0.5 2.0 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EAX95946.1 - 9.1e-05 22.5 1.0 0.00017 21.7 1.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EAX95946.1 - 0.00043 20.7 0.8 0.0027 18.1 0.8 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain NtCtMGAM_N PF16863.5 EAX95946.1 - 4.5 7.5 25.3 14 6.0 2.6 5.7 2 1 2 4 4 4 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Ank_2 PF12796.7 EAX95947.1 - 1.1e-73 243.8 7.5 6.9e-18 65.0 0.1 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX95947.1 - 4.9e-46 153.2 0.0 2.4e-05 24.6 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX95947.1 - 5.4e-39 132.1 0.0 8.2e-09 35.8 0.0 6.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95947.1 - 2.2e-37 122.8 0.0 0.00082 19.7 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX95947.1 - 9.2e-37 124.6 0.2 2.8e-07 30.7 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SnAPC_2_like PF11035.8 EAX95947.1 - 0.35 11.0 3.0 0.45 10.6 2.7 1.3 1 1 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Tup_N PF08581.10 EAX95948.1 - 0.026 14.8 5.5 0.026 14.8 5.5 8.6 4 3 3 7 7 7 0 Tup N-terminal DUF1192 PF06698.11 EAX95948.1 - 0.053 13.6 10.3 2.3 8.3 0.0 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) EmrE PF13536.6 EAX95949.1 - 0.023 14.3 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter Metallophos PF00149.28 EAX95950.1 - 1.1e-29 104.5 0.1 3e-29 103.0 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EAX95950.1 - 0.011 15.5 0.4 0.029 14.2 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX95950.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 EAX95951.1 - 3.5e-09 37.1 3.6 0.033 15.1 0.2 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX95951.1 - 1.7e-05 25.0 0.1 0.0031 17.8 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX95951.1 - 2e-05 24.6 0.0 0.00058 19.8 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Choline_kinase PF01633.20 EAX95952.1 - 0.014 15.0 1.6 0.096 12.3 0.2 2.2 2 1 0 2 2 2 0 Choline/ethanolamine kinase Glycos_trans_3N PF02885.17 EAX95952.1 - 0.17 11.7 0.1 0.37 10.7 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family, helical bundle domain IBD PF10416.9 EAX95953.1 - 4.7e-35 120.4 1.6 1e-34 119.3 0.5 1.8 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD HpcH_HpaI PF03328.14 EAX95953.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DLH PF01738.18 EAX95953.1 - 0.14 11.7 0.0 0.36 10.3 0.0 1.5 1 1 1 2 2 2 0 Dienelactone hydrolase family DUF4106 PF13388.6 EAX95955.1 - 8.8e-270 894.9 17.5 8.8e-270 894.9 17.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) DUF2960 PF11173.8 EAX95956.1 - 0.042 14.3 0.3 0.12 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) U-box PF04564.15 EAX95957.1 - 0.00015 21.8 0.2 0.00037 20.6 0.2 1.6 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.31 EAX95957.1 - 0.00098 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Presenilin PF01080.17 EAX95957.1 - 2.5 6.8 5.3 3.5 6.3 5.3 1.2 1 0 0 1 1 1 0 Presenilin ANAPC4_WD40 PF12894.7 EAX95958.1 - 4.9e-10 39.6 0.0 0.00037 20.7 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX95958.1 - 0.005 17.7 6.7 2.3 9.3 0.1 4.5 5 1 0 5 5 5 2 WD domain, G-beta repeat FAST_1 PF06743.15 EAX95958.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Kringle PF00051.18 EAX95960.1 - 0.073 13.4 0.5 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Kringle domain Ank_2 PF12796.7 EAX95962.1 - 5.1e-27 94.3 17.5 6.8e-11 42.6 1.1 4.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95962.1 - 5e-18 64.9 10.2 3.9e-06 27.0 0.3 6.6 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX95962.1 - 2.8e-17 62.9 6.0 3.5e-07 30.6 0.1 5.6 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX95962.1 - 3e-17 62.2 9.0 1.4e-06 28.4 0.5 6.3 6 1 1 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 EAX95962.1 - 4.6e-17 60.4 8.4 4.8e-05 23.4 0.2 7.0 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 EAX95962.1 - 3.1e-15 55.9 4.0 3.1e-15 55.9 4.0 4.1 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) RL PF17797.1 EAX95962.1 - 0.27 11.2 1.4 0.68 9.9 0.1 2.4 3 0 0 3 3 3 0 RL domain Myb_DNA-binding PF00249.31 EAX95964.1 - 1.2e-11 44.6 0.1 9e-11 41.8 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX95964.1 - 1.5e-09 38.0 2.6 1.5e-09 38.0 2.6 2.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX95964.1 - 8.7e-08 32.3 0.5 1.7e-07 31.3 0.5 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX95964.1 - 0.0033 17.3 10.6 0.0084 16.0 10.6 1.7 1 1 0 1 1 1 1 Myb DNA-binding like DUF5401 PF17380.2 EAX95964.1 - 0.05 11.7 5.3 0.051 11.7 5.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SRP9-21 PF05486.12 EAX95964.1 - 0.22 11.9 4.8 3.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Poxvirus_B22R_N PF13169.6 EAX95964.1 - 0.82 10.2 8.8 0.72 10.4 4.9 2.0 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal UPF0172 PF03665.13 EAX95964.1 - 1.4 9.0 5.1 2.1 8.3 5.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF3447 PF11929.8 EAX95965.1 - 1.3e-08 34.6 2.7 1.3e-08 34.6 2.7 4.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) TMEM154 PF15102.6 EAX95968.1 - 0.012 15.5 1.6 0.012 15.5 1.6 1.6 2 0 0 2 2 2 0 TMEM154 protein family Orf78 PF06024.12 EAX95968.1 - 0.021 15.1 1.2 0.045 14.0 1.2 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Sigma_reg_N PF13800.6 EAX95968.1 - 0.15 12.4 4.2 0.37 11.1 4.2 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5383 PF17355.2 EAX95968.1 - 0.15 12.4 0.5 0.26 11.6 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) LPD16 PF18830.1 EAX95969.1 - 0.1 12.5 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 Ribosomal_L35Ae PF01247.18 EAX95970.1 - 2.5e-33 114.1 0.0 3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EAX95970.1 - 0.073 13.3 0.0 5.8 7.2 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain EamA PF00892.20 EAX95971.1 - 3.8e-14 53.0 38.1 5.4e-08 33.1 14.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Choline_transpo PF04515.12 EAX95972.1 - 1.2e-10 41.1 38.3 4.2e-10 39.3 34.3 2.8 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF2873 PF11395.8 EAX95973.1 - 0.0079 16.0 0.9 0.0079 16.0 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2873) DUF4957 PF16318.5 EAX95973.1 - 0.19 11.6 14.8 0.33 10.9 1.5 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4957) Beta_helix PF13229.6 EAX95973.1 - 0.9 9.4 12.8 2.8e+02 1.3 12.8 2.5 1 1 0 1 1 1 0 Right handed beta helix region LRR_5 PF13306.6 EAX95974.1 - 1.4e-97 322.5 79.6 1.2e-26 93.2 2.6 6.1 1 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95974.1 - 1.5e-26 91.9 7.5 0.00072 19.3 0.0 8.0 5 2 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EAX95974.1 - 1e-07 32.1 13.6 0.095 13.2 0.5 7.4 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAX95974.1 - 4.8 7.4 15.0 14 6.0 0.7 5.6 5 2 0 5 5 5 0 FNIP Repeat LRR_5 PF13306.6 EAX95975.1 - 1.4e-19 70.3 13.6 7.9e-16 58.2 8.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95975.1 - 1.1e-09 37.9 0.1 0.00021 21.0 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAX95975.1 - 0.00037 20.8 0.1 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Peptidase_S28 PF05577.12 EAX95976.1 - 2.2e-89 300.2 3.3 2.2e-89 300.2 3.3 1.9 1 1 1 2 2 2 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EAX95976.1 - 0.0034 16.7 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Laminin_EGF PF00053.24 EAX95976.1 - 0.023 14.8 0.8 0.049 13.8 0.8 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 EAX95976.1 - 0.046 14.1 4.0 0.091 13.1 4.0 1.5 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 EAX95976.1 - 0.074 13.4 1.0 0.14 12.5 1.0 1.5 1 0 0 1 1 1 0 EGF-like domain TMEM154 PF15102.6 EAX95976.1 - 4.7 7.1 6.7 0.23 11.3 0.2 2.1 3 0 0 3 3 3 0 TMEM154 protein family IBD PF10416.9 EAX95977.1 - 3.4e-26 91.7 0.5 4.3e-26 91.4 0.5 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD HTH_56 PF18662.1 EAX95977.1 - 0.0071 16.4 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 2 Cch helix turn helix domain AAA_6 PF12774.7 EAX95977.1 - 0.026 13.5 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Trypan_PARP PF05887.11 EAX95978.1 - 0.042 13.8 12.0 0.043 13.8 12.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX95978.1 - 2.7 8.4 6.8 3 8.3 6.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX95979.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX95979.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain SH3_3 PF08239.11 EAX95980.1 - 2.1e-27 95.1 7.3 8.5e-14 51.6 0.5 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 EAX95980.1 - 1.7e-14 53.4 0.3 3.2e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain DUF261 PF03196.13 EAX95980.1 - 2.2e-05 24.6 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF261 SH3_2 PF07653.17 EAX95980.1 - 0.0035 17.0 0.2 0.013 15.1 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EAX95980.1 - 0.068 13.1 0.3 0.23 11.3 0.3 1.9 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 EAX95980.1 - 0.076 12.6 3.4 0.085 12.5 0.6 2.2 2 0 0 2 2 2 0 SH3 domain Gly_rich PF12810.7 EAX95981.1 - 7.2e-29 101.4 30.9 9.1e-29 101.1 30.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX95982.1 - 1.6e-17 64.2 8.8 2.1e-17 63.9 8.8 1.0 1 0 0 1 1 1 1 Glycine rich protein F5_F8_type_C PF00754.25 EAX95983.1 - 7.7e-07 29.3 0.0 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain SH3_3 PF08239.11 EAX95984.1 - 1.6e-27 95.5 12.4 3.9e-15 55.9 0.3 3.2 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_4 PF06347.13 EAX95984.1 - 3.3e-15 55.6 0.9 3.9e-10 39.4 0.1 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain DUF261 PF03196.13 EAX95984.1 - 2.7e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF261 SH3_2 PF07653.17 EAX95984.1 - 0.015 14.9 2.0 0.031 14.0 0.1 2.5 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.28 EAX95984.1 - 0.064 12.9 0.5 0.064 12.9 0.5 2.4 3 0 0 3 3 3 0 SH3 domain SH3_9 PF14604.6 EAX95984.1 - 0.066 13.1 1.4 0.14 12.0 0.3 2.2 2 0 0 2 2 2 0 Variant SH3 domain Gly_rich PF12810.7 EAX95985.1 - 6.2e-28 98.4 31.0 7.5e-28 98.1 31.0 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX95986.1 - 1.3e-55 186.8 49.0 5.7e-23 81.3 23.8 3.6 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95986.1 - 6.2e-14 51.5 15.7 0.0051 16.5 0.1 6.5 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EAX95986.1 - 0.006 17.0 12.8 2.4 8.7 1.6 6.4 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX95987.1 - 8.9e-56 187.3 50.2 5.8e-23 81.2 23.8 3.6 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95987.1 - 2.1e-14 53.0 15.2 0.0051 16.5 0.1 6.5 3 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EAX95987.1 - 0.0029 18.0 12.5 1.4 9.5 0.2 6.4 4 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX95988.1 - 8.6e-37 126.0 8.3 8.2e-31 106.6 3.4 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95988.1 - 1.9e-06 27.5 0.2 0.13 12.0 0.0 4.7 3 3 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EAX95988.1 - 0.00026 21.3 2.3 2.6 8.6 0.0 4.7 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) Gly_rich PF12810.7 EAX95989.1 - 3.9e-34 118.6 26.3 5.1e-34 118.3 26.3 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX95990.1 - 3.5e-54 182.2 37.0 1e-26 93.4 3.8 3.6 3 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95990.1 - 2.1e-08 33.8 8.9 0.27 11.0 0.6 6.3 4 2 2 6 6 6 5 Leucine rich repeat DUF4795 PF16043.5 EAX95994.1 - 0.0025 17.5 15.3 0.029 14.0 2.0 3.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4795) PTR PF12789.7 EAX95994.1 - 2.5 8.2 12.6 0.22 11.6 2.1 4.2 4 1 0 4 4 4 0 Phage tail repeat like DUF5623 PF18536.1 EAX95995.1 - 0.069 13.4 0.1 0.089 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAX95995.1 - 0.41 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Ank_2 PF12796.7 EAX95996.1 - 4.5e-15 56.0 0.2 1.4e-08 35.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX95996.1 - 7e-13 48.5 1.0 1.7e-06 28.2 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX95996.1 - 7e-12 44.4 3.1 0.00016 21.8 0.4 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX95996.1 - 1.1e-11 44.6 0.7 2e-05 24.8 0.6 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX95996.1 - 6.3e-11 42.6 0.7 3.4e-05 24.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.6 EAX95996.1 - 0.031 15.1 0.3 0.12 13.3 0.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Adeno_E4_34 PF04528.13 EAX95996.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region Gly_rich PF12810.7 EAX95997.1 - 6.3e-32 111.4 29.6 7.3e-32 111.2 29.6 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX95998.1 - 5.9e-27 94.2 17.1 7.4e-15 55.0 10.4 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX95998.1 - 4.5e-10 39.1 0.0 0.0018 18.0 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat Peptidase_C1 PF00112.23 EAX95999.1 - 2.8e-32 112.6 2.2 3.2e-32 112.4 2.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX95999.1 - 0.00042 19.2 0.6 0.00054 18.9 0.6 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Nitroreductase PF00881.24 EAX96000.1 - 1.4e-28 100.1 0.0 1.6e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAX96000.1 - 1.4e-08 34.6 0.2 0.044 13.3 0.0 3.0 1 1 1 3 3 3 3 Putative TM nitroreductase Gly_rich PF12810.7 EAX96001.1 - 3e-20 73.2 32.7 3.6e-20 72.9 32.7 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4108 PF13390.6 EAX96002.1 - 9e-62 207.2 8.3 1e-61 207.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) RNA_polI_A34 PF08208.11 EAX96003.1 - 0.68 10.0 14.5 0.62 10.1 14.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2897 PF11446.8 EAX96003.1 - 0.91 9.5 4.0 1.5 8.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S49_N PF08496.10 EAX96003.1 - 3.1 7.9 5.7 3.3 7.7 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mlf1IP PF10248.9 EAX96004.1 - 2.3e-09 37.4 10.7 1e-08 35.4 10.7 2.0 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein zf-BED PF02892.15 EAX96004.1 - 0.053 13.5 0.8 0.13 12.3 0.8 1.6 1 0 0 1 1 1 0 BED zinc finger COPIIcoated_ERV PF07970.12 EAX96005.1 - 3.1e-41 141.7 0.0 4.4e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX96005.1 - 1.4e-10 41.4 0.3 3.7e-10 40.0 0.3 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MatE PF01554.18 EAX96008.1 - 4.8e-32 110.8 21.8 1.9e-16 60.2 8.1 2.6 2 1 1 3 3 3 2 MatE LRR_5 PF13306.6 EAX96009.1 - 1.8e-47 160.5 44.9 3.1e-24 85.4 7.0 4.5 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96009.1 - 2.6e-09 36.7 11.0 8.6e-05 22.2 0.3 5.1 2 1 4 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAX96009.1 - 0.15 12.6 17.8 1.6 9.2 0.1 6.2 5 3 1 6 6 6 0 Leucine Rich repeats (2 copies) NOG1_N PF17835.1 EAX96010.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain DUF3502 PF12010.8 EAX96010.1 - 0.11 13.2 0.0 0.41 11.3 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3502) DNA_pol_B_2 PF03175.13 EAX96011.1 - 3.4e-24 85.5 7.3 2.1e-23 82.9 7.3 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX96012.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX96012.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAX96013.1 - 0.0055 17.1 1.1 0.0061 17.0 0.6 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX96013.1 - 4.9 7.8 6.8 11 6.7 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX96014.1 - 0.012 15.6 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX96015.1 - 0.079 12.9 10.7 0.12 12.3 10.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX96016.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX96016.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Amidase02_C PF12123.8 EAX96017.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX96017.1 - 0.12 12.2 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Peptidase_M8 PF01457.16 EAX96018.1 - 1.6e-19 70.0 0.0 2.7e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin Pox_A14 PF05767.12 EAX96018.1 - 0.034 14.3 0.2 0.06 13.5 0.2 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Glycophorin_A PF01102.18 EAX96018.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Peptidase_M56 PF05569.11 EAX96018.1 - 0.064 12.4 0.1 0.95 8.6 0.0 2.2 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF3810 PF12725.7 EAX96018.1 - 0.08 12.3 0.6 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) OAD_gamma PF04277.13 EAX96018.1 - 0.098 13.3 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_M8 PF01457.16 EAX96019.1 - 1.8e-24 86.3 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin STE2 PF02116.15 EAX96019.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Chordopox_A13L PF05961.11 EAX96019.1 - 0.1 12.8 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Adeno_E3_CR2 PF02439.15 EAX96019.1 - 0.11 12.3 2.7 0.19 11.5 2.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rax2 PF12768.7 EAX96019.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Peptidase_M8 PF01457.16 EAX96020.1 - 3.4e-32 111.8 0.0 6.7e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Leishmanolysin Shisa PF13908.6 EAX96020.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 EAX96020.1 - 0.17 11.8 0.4 0.36 10.8 0.4 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Adeno_E3_CR2 PF02439.15 EAX96020.1 - 2.1 8.2 8.7 0.12 12.1 2.2 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EAX96020.1 - 4.7 6.7 8.8 0.28 10.6 2.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LRR_6 PF13516.6 EAX96021.1 - 2.8e-08 33.2 0.2 1.2e-05 24.9 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EAX96021.1 - 0.0013 19.0 1.9 8.9 7.3 0.2 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 EAX96021.1 - 0.012 16.0 11.5 0.39 11.2 0.6 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Carm_PH PF17888.1 EAX96021.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_8 PF13855.6 EAX96021.1 - 0.28 11.0 3.0 3.5 7.5 0.7 3.2 2 0 0 2 2 2 0 Leucine rich repeat DUF1160 PF06648.11 EAX96021.1 - 1.2 9.1 4.3 18 5.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) ApoLp-III PF07464.11 EAX96022.1 - 0.0021 18.2 5.6 0.0095 16.0 5.6 1.7 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 EAX96022.1 - 0.035 14.4 4.0 0.074 13.3 2.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 EAX96022.1 - 0.035 13.9 2.0 0.072 12.9 1.9 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TolA_bind_tri PF16331.5 EAX96022.1 - 0.056 13.5 0.5 0.37 10.9 0.1 2.3 2 1 1 3 3 3 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EAX96022.1 - 0.083 13.4 7.6 0.78 10.3 3.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Bap31_Bap29_C PF18035.1 EAX96022.1 - 0.14 12.2 0.4 0.32 11.0 0.0 1.9 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CENP-F_leu_zip PF10473.9 EAX96022.1 - 0.29 11.1 5.0 1 9.4 1.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 EAX96022.1 - 0.35 11.3 2.9 2.2 8.8 2.1 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper AI-2E_transport PF01594.16 EAX96022.1 - 0.57 9.3 1.6 0.77 8.8 1.2 1.3 1 1 0 1 1 1 0 AI-2E family transporter SEP PF08059.13 EAX96023.1 - 3.3e-21 75.6 0.2 8e-21 74.4 0.2 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 EAX96023.1 - 8.3e-09 35.1 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EAX96023.1 - 0.00092 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.23 EAX96023.1 - 0.023 14.4 0.1 0.2 11.4 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin family Rad60-SLD PF11976.8 EAX96023.1 - 0.056 13.3 0.1 12 5.8 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TAP_C PF03943.13 EAX96023.1 - 0.17 11.6 0.1 4.5 7.0 0.0 2.9 3 0 0 3 3 3 0 TAP C-terminal domain Syntaxin-18_N PF10496.9 EAX96023.1 - 4.2 7.7 6.6 2.2 8.6 2.5 2.6 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus tRNA_SAD PF07973.14 EAX96024.1 - 5.5e-12 45.6 2.1 7.4e-12 45.2 1.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain AIG1 PF04548.16 EAX96025.1 - 0.092 12.1 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 AIG1 family JmjN PF02375.17 EAX96025.1 - 2.4 8.2 4.2 27 4.8 0.0 3.9 4 0 0 4 4 4 0 jmjN domain PSP PF04046.16 EAX96027.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TRM PF02005.16 EAX96028.1 - 4.4e-24 85.4 0.0 5.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TRM PF02005.16 EAX96029.1 - 3.7e-55 187.6 0.4 4.2e-55 187.4 0.4 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EAX96029.1 - 2.2e-09 37.4 0.1 2.7e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EAX96029.1 - 2.9e-05 23.6 0.3 3.8e-05 23.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EAX96029.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EAX96029.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 EAX96029.1 - 0.031 13.3 0.2 0.036 13.0 0.2 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EAX96029.1 - 0.039 14.7 0.0 0.065 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Lipoprotein_1 PF00820.19 EAX96029.1 - 0.089 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein GPS2_interact PF15784.5 EAX96030.1 - 0.11 13.0 0.9 0.14 12.6 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX96031.1 - 0.06 13.3 10.1 0.085 12.8 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PapD_N PF00345.20 EAX96032.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Grp7_allergen PF16984.5 EAX96033.1 - 0.027 14.5 0.3 0.04 14.0 0.3 1.4 1 1 0 1 1 1 0 Group 7 allergen T4_Rnl2_C PF18043.1 EAX96033.1 - 0.24 11.6 1.5 2.8 8.2 1.5 2.0 1 1 0 1 1 1 0 T4 RNA ligase 2 C-terminal DUF3839 PF12943.7 EAX96034.1 - 2.8e-154 511.5 13.1 3.5e-154 511.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX96034.1 - 0.052 14.0 6.1 0.18 12.3 1.2 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX96034.1 - 0.16 11.8 0.9 0.54 10.1 0.4 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Amidase02_C PF12123.8 EAX96036.1 - 0.0038 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX96037.1 - 2.9e-71 238.9 3.0 4e-71 238.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) ERM PF00769.19 EAX96038.1 - 0.00057 19.8 9.3 0.00071 19.5 9.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Blt1 PF12754.7 EAX96038.1 - 0.0025 18.1 4.6 0.0025 18.1 4.6 1.5 1 1 0 1 1 1 1 Blt1 N-terminal domain V_ATPase_I PF01496.19 EAX96038.1 - 0.088 10.7 14.7 0.11 10.4 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 EAX96038.1 - 0.31 11.2 14.1 0.72 10.0 4.0 3.3 1 1 2 3 3 3 0 bZIP transcription factor DUF2252 PF10009.9 EAX96038.1 - 0.48 9.4 5.6 0.62 9.1 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) FAM76 PF16046.5 EAX96038.1 - 1 8.6 15.4 1.1 8.5 15.4 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 EAX96038.1 - 1.3 9.5 17.3 3.8 8.1 17.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 EAX96038.1 - 5.7 5.4 22.4 0.63 8.6 13.3 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 EAX96038.1 - 7.2 7.1 17.7 1.6 9.2 5.4 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 EAX96038.1 - 8 6.9 12.8 17 5.8 5.8 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vac14_Fab1_bd PF12755.7 EAX96039.1 - 0.004 17.7 7.7 1.2 9.7 0.3 5.2 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAX96039.1 - 0.0044 17.5 0.0 11 6.6 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat TIP120 PF08623.10 EAX96039.1 - 0.0051 16.6 3.8 0.72 9.6 0.1 4.5 3 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 EAX96039.1 - 0.0074 16.3 23.4 0.32 11.0 0.2 6.2 4 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.6 EAX96039.1 - 0.06 13.7 14.4 5.7 7.2 0.1 5.6 3 2 1 5 5 5 0 FANCI solenoid 2 RTP1_C1 PF10363.9 EAX96039.1 - 0.17 12.0 0.7 6.2 7.0 0.1 3.7 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1981 PF09324.10 EAX96039.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) DUF445 PF04286.12 EAX96039.1 - 3.2 7.4 13.3 8.9 6.0 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Ank_2 PF12796.7 EAX96040.1 - 8.3e-11 42.3 2.8 0.19 12.3 0.0 5.2 4 2 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96040.1 - 1.2e-08 35.3 0.9 0.18 12.4 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96040.1 - 1.1e-07 31.6 2.3 0.12 13.0 0.0 6.8 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EAX96040.1 - 0.0066 16.9 0.0 7.2 7.3 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX96042.1 - 2.9e-13 50.0 0.2 6.6e-11 42.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96042.1 - 6.3e-13 48.7 0.0 1.6e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96042.1 - 1.2e-12 46.8 0.9 1.1e-05 25.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX96042.1 - 3.1e-11 43.7 0.1 4.1e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96042.1 - 1.1e-10 41.4 0.3 1.1e-05 25.7 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat IBD PF10416.9 EAX96043.1 - 1.4e-37 128.6 0.1 2.3e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD THB PF18362.1 EAX96043.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain zinc_ribbon_10 PF10058.9 EAX96043.1 - 0.086 12.6 0.7 0.43 10.3 0.1 2.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3839 PF12943.7 EAX96044.1 - 8.4e-156 516.6 14.2 1e-155 516.2 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96044.1 - 0.05 14.1 0.8 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Fez1 Glu-tRNAGln PF02686.15 EAX96044.1 - 0.24 11.7 1.8 0.97 9.8 0.5 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX96044.1 - 0.54 10.8 5.9 0.35 11.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX96044.1 - 0.86 10.1 7.8 3.5 8.2 1.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX96045.1 - 6.4e-47 157.4 29.2 2.5e-32 110.7 14.1 5.1 3 2 1 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX96045.1 - 0.029 14.1 0.7 0.15 11.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX96045.1 - 0.043 14.0 0.8 0.28 11.5 0.0 2.6 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain TMP PF05017.14 EAX96047.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96048.1 - 0.073 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP IBD PF10416.9 EAX96049.1 - 3.7e-29 101.3 1.1 4.8e-29 101.0 1.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD ubiquitin PF00240.23 EAX96050.1 - 1.5e-09 37.5 0.8 2.5e-09 36.7 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EAX96050.1 - 0.0047 16.7 0.2 0.014 15.2 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EAX96050.1 - 0.014 15.4 0.2 0.53 10.4 0.1 2.9 2 1 0 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX96050.1 - 0.16 12.4 1.5 0.48 10.8 0.1 2.4 3 0 0 3 3 3 0 Ubiquitin-like domain Metallophos PF00149.28 EAX96051.1 - 3.8e-33 115.7 0.1 5.6e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EAX96051.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) GNAT_acetyltran PF12746.7 EAX96052.1 - 8.5e-10 38.6 0.4 1.4e-09 37.9 0.4 1.6 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EAX96052.1 - 5.9e-07 29.6 0.1 7.3e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX96052.1 - 5.9e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 EAX96052.1 - 4.6e-06 26.6 0.0 8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX96052.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAX96052.1 - 0.003 17.8 0.0 0.0077 16.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF2846 PF11008.8 EAX96052.1 - 0.076 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Lipid_bd PF12888.7 EAX96052.1 - 0.14 12.6 0.1 15 6.1 0.0 2.3 1 1 1 2 2 2 0 Lipid-binding putative hydrolase Ovate PF04844.13 EAX96053.1 - 0.32 11.0 7.8 3.7 7.6 0.9 3.6 3 0 0 3 3 3 0 Transcriptional repressor, ovate Nup96 PF12110.8 EAX96054.1 - 0.055 12.6 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 TrbL PF04610.14 EAX96054.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Metallophos PF00149.28 EAX96055.1 - 4.5e-26 92.6 0.1 6.6e-26 92.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EAX96055.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) WD40 PF00400.32 EAX96056.1 - 1.6e-17 63.5 7.7 2.7e-06 28.0 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EAX96056.1 - 3.6e-12 46.6 5.3 8.5e-12 45.4 5.3 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EAX96056.1 - 3.4e-11 43.3 0.0 0.00063 20.0 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX96056.1 - 2e-07 30.7 0.0 5.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 WD40-like domain Frtz PF11768.8 EAX96056.1 - 0.0025 16.2 0.0 0.042 12.2 0.0 2.4 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz T4_Rnl2_C PF18043.1 EAX96056.1 - 0.14 12.4 0.6 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal EF-hand_7 PF13499.6 EAX96057.1 - 5.8e-08 33.1 0.7 1.5e-07 31.7 0.7 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EAX96057.1 - 1.4e-06 27.4 0.3 0.031 13.8 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EAX96057.1 - 1.3e-05 24.4 0.3 0.076 12.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EAX96057.1 - 1.8e-05 24.3 0.2 0.074 13.0 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EAX96057.1 - 0.0013 18.5 0.2 0.58 10.0 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair ANAPC4_WD40 PF12894.7 EAX96057.1 - 0.0058 16.9 0.2 2.5 8.4 0.0 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX96057.1 - 0.025 15.4 6.7 2.3 9.3 0.3 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Fe-ADH PF00465.19 EAX96058.1 - 8.2e-37 126.9 0.0 1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAX96058.1 - 8.3e-05 22.4 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Ank_4 PF13637.6 EAX96059.1 - 4.9e-15 55.7 0.2 3.9e-11 43.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96059.1 - 7e-14 51.7 0.2 1.3e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96059.1 - 1.2e-12 48.3 0.0 1.4e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96059.1 - 1.3e-11 44.4 0.1 2.3e-08 34.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX96059.1 - 1.5e-07 31.2 0.3 4.4e-05 23.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DDHD PF02862.17 EAX96059.1 - 0.04 14.1 0.0 0.04 14.1 0.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF3447 PF11929.8 EAX96060.1 - 3.4e-27 94.2 0.8 3.4e-27 94.2 0.8 4.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96060.1 - 7.2e-26 90.6 2.1 4.2e-12 46.5 0.2 3.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96060.1 - 1.5e-23 82.1 2.2 1e-06 28.9 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EAX96060.1 - 6.7e-22 77.6 0.2 7.1e-08 32.9 0.0 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96060.1 - 3.3e-20 70.0 3.5 0.00042 20.5 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX96060.1 - 2.9e-14 52.9 0.2 0.00013 22.2 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Glyco_hydro_125 PF06824.11 EAX96060.1 - 0.017 14.0 0.4 0.022 13.7 0.4 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) Frag1 PF10277.9 EAX96062.1 - 6.8e-24 84.6 27.6 7.7e-24 84.4 27.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1981 PF09324.10 EAX96063.1 - 0.0022 17.8 0.6 0.0022 17.8 0.6 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Knl1_RWD_C PF18210.1 EAX96063.1 - 0.07 13.6 0.0 0.07 13.6 0.0 3.7 4 0 0 4 4 4 0 Knl1 RWD C-terminal domain Cnd1 PF12717.7 EAX96063.1 - 0.08 13.0 0.0 0.08 13.0 0.0 6.3 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 NAC PF01849.18 EAX96065.1 - 1.8e-08 34.2 0.0 2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 NAC domain DnaJ PF00226.31 EAX96066.1 - 6.8e-20 71.0 2.4 6.8e-20 71.0 2.4 2.1 2 0 0 2 2 2 1 DnaJ domain DUF2207 PF09972.9 EAX96066.1 - 0.0022 16.8 4.7 0.0025 16.6 4.5 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) CcmH PF03918.14 EAX96066.1 - 0.31 10.3 2.4 0.25 10.6 0.8 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein AgrB PF04647.15 EAX96066.1 - 2.5 7.4 11.3 1.8 7.8 1.2 2.7 3 0 0 3 3 3 0 Accessory gene regulator B Ribosomal_S30 PF04758.14 EAX96066.1 - 2.6 8.3 6.1 0.7 10.1 2.2 2.1 2 0 0 2 2 2 0 Ribosomal protein S30 Amidoligase_2 PF12224.8 EAX96067.1 - 0.025 14.3 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 Putative amidoligase enzyme ING PF12998.7 EAX96067.1 - 0.025 15.2 2.0 0.036 14.6 0.8 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sec8_exocyst PF04048.14 EAX96067.1 - 0.35 10.8 5.8 0.3 11.0 1.9 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.10 EAX96067.1 - 3.9 7.6 10.4 4.7 7.4 2.6 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RabGAP-TBC PF00566.18 EAX96068.1 - 1.6e-44 152.2 2.4 2.8e-44 151.3 2.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol3_finger PF17657.1 EAX96068.1 - 0.0052 16.2 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain DUF4107 PF13389.6 EAX96069.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAX96070.1 - 4.3e-157 520.8 14.7 5.5e-157 520.4 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96070.1 - 0.09 13.2 2.4 0.12 12.8 0.6 1.9 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAX96070.1 - 0.11 12.4 1.8 0.27 11.1 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX96070.1 - 0.31 11.5 5.7 2.1 8.9 0.3 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YmaF PF12788.7 EAX96072.1 - 0.12 13.0 1.8 1.2 9.7 1.8 2.0 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX96072.1 - 0.57 10.5 7.6 1.2 9.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat TMP PF05017.14 EAX96074.1 - 0.054 14.1 5.6 6.3 7.9 0.8 3.1 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX96074.1 - 7.9 6.5 8.7 8.5 6.4 8.7 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX96075.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DDE_1 PF03184.19 EAX96076.1 - 5.3e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HECT PF00632.25 EAX96077.1 - 1.8e-61 208.3 0.1 4.1e-61 207.1 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SRP_TPR_like PF17004.5 EAX96077.1 - 0.032 14.2 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Putative TPR-like repeat Med31 PF05669.12 EAX96077.1 - 0.074 13.1 0.5 2.1 8.4 0.6 2.8 2 0 0 2 2 2 0 SOH1 RNR_N PF08343.10 EAX96077.1 - 0.21 11.6 1.2 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal CENP-S PF15630.6 EAX96078.1 - 8.1e-12 45.4 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAX96078.1 - 0.004 17.3 0.2 0.0071 16.5 0.2 1.6 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold GED PF02212.18 EAX96078.1 - 0.11 12.7 1.2 0.28 11.4 1.1 1.8 1 1 0 1 1 1 0 Dynamin GTPase effector domain WD40 PF00400.32 EAX96079.1 - 1.9e-10 41.1 1.3 0.00072 20.3 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX96079.1 - 3.8e-05 23.9 0.0 5.6 7.3 0.0 4.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EAX96079.1 - 0.00049 20.1 0.2 0.21 11.7 0.0 3.1 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EAX96079.1 - 0.0093 15.3 0.0 0.031 13.6 0.0 1.7 1 1 1 2 2 2 1 WD40-like domain Filament PF00038.21 EAX96079.1 - 0.044 13.4 3.3 0.068 12.7 3.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein Ndc1_Nup PF09531.10 EAX96079.1 - 0.053 12.2 9.8 0.066 11.9 9.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Striatin PF08232.12 EAX96079.1 - 0.76 10.4 15.7 2.7 8.5 15.7 1.9 1 1 0 1 1 1 0 Striatin family DUF3450 PF11932.8 EAX96079.1 - 1.2 8.4 7.7 1.7 7.9 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EAX96079.1 - 1.3 9.2 11.9 0.048 13.9 5.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1043 PF06295.12 EAX96079.1 - 4.2 7.4 10.5 11 6.0 10.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TMPIT PF07851.13 EAX96079.1 - 5.1 6.3 5.5 10 5.3 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein AKAP7_RIRII_bdg PF10470.9 EAX96079.1 - 5.2 7.2 9.1 3.2 7.9 3.0 2.5 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Jnk-SapK_ap_N PF09744.9 EAX96079.1 - 9.6 6.4 13.3 3.4 7.9 9.9 2.0 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Ank_4 PF13637.6 EAX96080.1 - 1.6e-53 178.4 28.1 9.8e-13 48.4 0.1 7.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96080.1 - 1.9e-43 146.9 21.8 3.7e-17 62.7 4.0 4.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96080.1 - 3.8e-42 140.9 26.5 5.2e-07 29.8 0.2 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 EAX96080.1 - 6e-42 136.8 18.6 4.5e-05 23.5 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAX96080.1 - 5.4e-40 134.9 34.0 9e-10 38.6 0.6 6.4 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96081.1 - 5.6e-59 196.7 28.6 2e-16 60.4 0.5 6.4 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96081.1 - 2e-42 143.0 12.8 4e-12 46.4 0.0 8.0 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX96081.1 - 1.1e-40 136.3 16.5 6.4e-06 26.4 0.0 10.2 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EAX96081.1 - 1.7e-38 126.2 21.7 0.00099 19.4 0.0 11.5 11 1 1 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EAX96081.1 - 1.8e-32 110.9 15.3 3.4e-08 33.6 0.0 8.8 5 2 4 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96081.1 - 1.1e-23 83.0 41.5 3.3e-23 81.4 8.4 6.5 4 3 2 7 7 7 4 Domain of unknown function (DUF3447) ScdA_N PF04405.14 EAX96081.1 - 0.069 12.8 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) Ank_2 PF12796.7 EAX96082.1 - 3e-86 284.1 32.3 2.8e-17 63.1 0.3 8.2 3 1 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96082.1 - 1.6e-78 258.1 17.7 3.5e-12 46.6 0.0 10.7 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX96082.1 - 3.7e-69 226.4 29.5 1.3e-08 34.9 0.1 13.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.6 EAX96082.1 - 3.2e-63 202.2 29.5 3.4e-06 27.0 0.1 15.3 15 1 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 EAX96082.1 - 1e-59 197.8 32.1 1.1e-10 41.5 0.1 11.1 4 3 10 14 14 14 11 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96082.1 - 6.3e-37 125.4 5.9 6.3e-37 125.4 5.9 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) GATase_7 PF13537.6 EAX96082.1 - 0.047 13.6 0.0 20 5.1 0.0 4.5 5 1 0 5 5 5 0 Glutamine amidotransferase domain PH_8 PF15409.6 EAX96082.1 - 0.074 13.3 0.2 32 4.9 0.0 3.8 3 2 1 4 4 4 0 Pleckstrin homology domain DUF4268 PF14088.6 EAX96082.1 - 0.075 12.9 1.6 43 4.0 0.0 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4268) Ank_2 PF12796.7 EAX96083.1 - 1e-99 327.3 47.3 1.5e-16 60.7 4.7 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96083.1 - 4.1e-83 272.8 15.3 4.1e-13 49.6 0.1 11.7 4 2 7 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX96083.1 - 2.2e-78 255.6 12.7 8.7e-07 29.1 0.0 14.1 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 EAX96083.1 - 6.5e-66 210.4 11.4 3.2e-05 24.0 0.0 14.1 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 EAX96083.1 - 5.3e-57 189.1 10.8 1e-11 44.8 0.1 9.8 4 2 5 11 11 11 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96083.1 - 7.7e-35 118.7 12.5 3e-34 116.8 4.3 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX96083.1 - 9.5e-05 22.6 0.0 2 8.7 0.0 4.4 3 2 2 5 5 5 2 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAX96083.1 - 0.029 14.6 0.2 49 4.3 0.0 4.8 4 2 3 7 7 7 0 Pleckstrin homology domain DUF5535 PF17687.1 EAX96083.1 - 0.16 12.1 0.0 22 5.3 0.0 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5535) Ank_2 PF12796.7 EAX96084.1 - 7.6e-81 266.8 55.7 2.3e-14 53.8 3.7 10.5 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96084.1 - 1.6e-80 262.3 27.4 1.1e-07 32.0 0.1 15.0 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.6 EAX96084.1 - 2.1e-72 238.6 32.6 4.6e-09 36.6 0.1 13.5 3 1 12 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96084.1 - 1.5e-61 197.0 22.9 3.1e-06 27.1 0.0 16.1 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 EAX96084.1 - 2.3e-55 183.9 15.8 4e-08 33.4 0.1 11.0 6 3 6 12 12 12 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96084.1 - 2.6e-38 129.8 4.6 2.6e-38 129.8 4.6 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAX96084.1 - 0.0083 16.3 1.0 29 4.8 0.0 4.5 4 1 1 5 5 5 0 Centrosomal spindle body, CEP44 PH_8 PF15409.6 EAX96084.1 - 0.013 15.8 0.5 44 4.5 0.0 5.2 2 2 5 8 8 8 0 Pleckstrin homology domain LPD5 PF18799.1 EAX96084.1 - 0.3 11.5 6.5 6.5 7.2 0.4 3.4 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 5 Ank_4 PF13637.6 EAX96085.1 - 1e-59 198.2 13.0 1.1e-10 41.8 0.0 10.7 5 2 7 12 12 12 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96085.1 - 3.3e-57 191.0 18.6 1.6e-13 51.0 0.0 7.4 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96085.1 - 4.7e-50 167.0 11.2 2.4e-12 46.8 0.4 8.1 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX96085.1 - 1.4e-46 155.0 19.9 1.7e-06 28.2 0.5 11.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 EAX96085.1 - 2.2e-44 144.3 19.3 9.7e-06 25.6 0.1 12.0 13 0 0 13 13 13 9 Ankyrin repeat DUF3447 PF11929.8 EAX96085.1 - 2.7e-35 120.1 21.1 5.6e-34 115.9 2.7 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF3447) BshC PF10079.9 EAX96085.1 - 0.0015 17.3 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Auto_anti-p27 PF06677.12 EAX96086.1 - 0.072 13.3 5.8 0.14 12.3 5.8 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 EAX96086.1 - 0.5 10.4 9.3 0.072 13.1 4.9 1.8 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L32p PF01783.23 EAX96086.1 - 4.5 7.6 8.0 0.39 11.0 2.8 1.8 2 0 0 2 2 2 0 Ribosomal L32p protein family Fis1_TPR_N PF14852.6 EAX96087.1 - 0.058 13.1 0.1 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat Xpo1 PF08389.12 EAX96087.1 - 0.1 12.6 4.4 0.14 12.2 0.4 3.4 3 0 0 3 3 3 0 Exportin 1-like protein MULE PF10551.9 EAX96089.1 - 0.032 14.6 1.7 0.13 12.7 0.1 2.7 3 0 0 3 3 3 0 MULE transposase domain DUF2960 PF11173.8 EAX96089.1 - 0.043 14.3 0.3 0.11 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) HD_2 PF12917.7 EAX96090.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF4108 PF13390.6 EAX96091.1 - 1.3e-60 203.5 8.5 1.5e-60 203.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) KilA-N PF04383.13 EAX96093.1 - 1.4e-33 115.0 1.6 1.8e-33 114.7 0.0 2.0 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAX96093.1 - 0.0045 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX96093.1 - 0.42 11.1 5.7 1.9 9.0 1.6 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ank_2 PF12796.7 EAX96096.1 - 1.7e-58 195.2 26.5 6.1e-18 65.2 1.2 5.6 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96096.1 - 8.2e-45 149.4 8.1 4.1e-08 33.3 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX96096.1 - 2.4e-39 133.2 7.4 1.6e-08 34.9 0.0 8.5 5 1 5 10 10 10 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96096.1 - 1.2e-30 105.3 5.6 1.2e-30 105.3 5.6 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX96096.1 - 3.5e-30 103.7 5.4 2.7e-10 40.3 0.1 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96096.1 - 1.7e-26 89.3 5.2 1.2e-05 25.3 0.0 8.0 7 0 0 7 7 7 5 Ankyrin repeat Mic1 PF07035.12 EAX96096.1 - 0.045 13.5 1.4 0.76 9.5 0.1 3.0 3 1 0 3 3 3 0 Colon cancer-associated protein Mic1-like YodL PF14191.6 EAX96096.1 - 0.073 13.9 2.6 1 10.2 0.2 3.2 3 1 0 3 3 3 0 YodL-like ATP13 PF12921.7 EAX96096.1 - 0.94 9.3 5.5 0.29 11.0 1.4 2.2 2 1 0 2 2 2 0 Mitochondrial ATPase expression zf-UBR PF02207.20 EAX96097.1 - 0.00066 19.8 18.7 0.0014 18.7 18.7 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Mis14 PF08641.12 EAX96098.1 - 0.013 15.9 0.0 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DUF5071 PF16804.5 EAX96098.1 - 0.028 14.7 2.8 2.1 8.6 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) Type2_restr_D3 PF16902.5 EAX96098.1 - 0.089 12.7 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Histone PF00125.24 EAX96099.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX96099.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX96099.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX96099.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAX96100.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX96100.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX96100.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX96100.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX96100.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX96100.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX96100.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX96100.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Ank_4 PF13637.6 EAX96101.1 - 7.8e-67 220.9 24.8 3.7e-10 40.1 0.1 12.4 5 2 8 13 13 13 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96101.1 - 1.4e-65 217.9 38.7 1.8e-14 54.1 3.2 7.7 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96101.1 - 2.2e-63 208.1 27.1 1.1e-07 32.0 0.2 11.0 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 EAX96101.1 - 3.8e-51 165.1 19.1 1.8e-05 24.8 0.1 11.8 11 1 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 EAX96101.1 - 2.6e-42 142.3 16.0 2.1e-10 40.6 0.2 7.6 2 1 4 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96101.1 - 3.8e-31 106.8 6.4 3.8e-31 106.8 6.4 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX96101.1 - 0.033 14.3 6.0 49 4.2 0.1 5.8 5 1 2 7 7 7 0 Protein of unknown function (DUF3718) RL PF17797.1 EAX96101.1 - 0.055 13.4 6.9 15 5.7 0.3 5.3 5 0 0 5 5 5 0 RL domain PrpR_N PF06506.11 EAX96101.1 - 0.17 11.4 1.1 3.7 7.1 0.0 3.6 3 1 2 5 5 5 0 Propionate catabolism activator ATP13 PF12921.7 EAX96101.1 - 3.6 7.5 6.8 4.8 7.1 0.2 3.2 3 1 1 4 4 4 0 Mitochondrial ATPase expression DPM3 PF08285.11 EAX96102.1 - 0.16 12.2 0.6 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3447 PF11929.8 EAX96103.1 - 0.00017 21.5 0.1 0.00017 21.5 0.1 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96103.1 - 0.01 16.4 0.1 0.63 10.7 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) TAF6_C PF07571.13 EAX96104.1 - 8.2e-09 35.7 0.0 1.7e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain SBDS_C PF09377.10 EAX96105.1 - 7.8e-26 90.4 1.2 1.4e-25 89.5 1.2 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EAX96105.1 - 3.6e-23 81.4 0.6 8.2e-23 80.3 0.6 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Glyco_transf_8 PF01501.20 EAX96106.1 - 1.9e-09 37.5 1.8 0.00061 19.4 0.1 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EAX96106.1 - 0.003 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 EAX96106.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Ank_4 PF13637.6 EAX96107.1 - 5e-39 132.2 0.4 2e-06 28.2 0.0 7.9 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96107.1 - 3e-37 127.1 9.3 9.4e-11 42.2 0.0 5.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96107.1 - 2.7e-27 94.5 1.3 8.3e-09 35.5 0.3 6.1 3 3 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX96107.1 - 7.5e-26 89.4 2.0 0.00033 21.0 0.1 9.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 EAX96107.1 - 3.5e-23 79.2 0.6 0.0093 16.4 0.1 9.2 9 1 0 9 9 9 5 Ankyrin repeat L51_S25_CI-B8 PF05047.16 EAX96107.1 - 0.0072 16.2 0.1 0.98 9.4 0.0 3.3 3 0 0 3 3 3 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2802 PF10975.8 EAX96107.1 - 0.026 14.6 0.1 0.63 10.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Trp_ring PF18669.1 EAX96107.1 - 0.16 12.2 0.5 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain S1-P1_nuclease PF02265.16 EAX96108.1 - 9.9e-10 38.7 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease OS-D PF03392.13 EAX96108.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Peptidase_S8 PF00082.22 EAX96109.1 - 3.5e-16 59.3 0.0 5.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family PRO8NT PF08082.11 EAX96110.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain PTR PF12789.7 EAX96112.1 - 1.7e-101 332.2 74.8 2.6e-32 110.7 15.3 5.6 2 2 3 5 5 5 4 Phage tail repeat like Apolipoprotein PF01442.18 EAX96112.1 - 0.027 14.4 2.3 0.2 11.5 2.3 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4116 PF13475.6 EAX96112.1 - 0.049 13.4 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX96112.1 - 0.1 12.8 1.5 0.47 10.7 0.0 2.9 3 1 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain DUF4795 PF16043.5 EAX96112.1 - 0.19 11.3 11.3 4.5 6.8 10.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2785 PF10978.8 EAX96112.1 - 0.41 10.4 6.3 3 7.6 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) AviRa PF11599.8 EAX96112.1 - 1.4 8.4 7.1 1.4 8.4 0.7 2.6 1 1 2 3 3 3 0 RRNA methyltransferase AviRa DDE_Tnp_4 PF13359.6 EAX96113.1 - 4.1e-28 98.1 0.1 5e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX96113.1 - 4.4e-13 49.4 0.1 6.6e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 EAX96113.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain TPR_MLP1_2 PF07926.12 EAX96114.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX96114.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX96114.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PTR PF12789.7 EAX96115.1 - 6.6e-13 48.5 26.4 2.1e-08 34.1 4.7 5.1 5 0 0 5 5 5 3 Phage tail repeat like Collagen PF01391.18 EAX96115.1 - 6.4e-06 25.8 11.3 1.2e-05 25.0 11.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX96115.1 - 0.021 14.9 5.3 0.028 14.5 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RecG_N PF17190.4 EAX96115.1 - 0.081 13.7 2.7 51 4.7 0.0 4.1 4 0 0 4 4 4 0 RecG N-terminal helical domain Amidase02_C PF12123.8 EAX96117.1 - 0.0025 17.5 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX96118.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX96118.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DDE_Tnp_4 PF13359.6 EAX96120.1 - 5.1e-28 97.7 0.1 6.3e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX96120.1 - 9.3e-13 48.3 0.1 1.4e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 EAX96120.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain LRR_5 PF13306.6 EAX96121.1 - 3.5e-142 466.7 105.0 1.5e-27 96.1 8.7 10.1 5 4 5 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96121.1 - 3.1e-28 97.3 6.8 0.0097 15.7 0.0 14.0 11 4 3 15 15 15 10 Leucine rich repeat LRR_4 PF12799.7 EAX96121.1 - 8.4e-08 32.4 7.3 5.8 7.5 0.0 9.4 9 1 1 10 10 10 2 Leucine Rich repeats (2 copies) RET_CLD4 PF17813.1 EAX96121.1 - 0.052 13.8 1.1 11 6.3 0.1 2.9 2 0 0 2 2 2 0 RET Cadherin like domain 4 PI-PLC-X PF00388.19 EAX96121.1 - 0.073 12.7 0.9 19 4.8 0.1 4.6 3 2 2 5 5 5 0 Phosphatidylinositol-specific phospholipase C, X domain HEPN_RES_NTD1 PF18870.1 EAX96122.1 - 0.09 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 DpnI_C PF17726.1 EAX96123.1 - 0.024 14.8 2.4 0.31 11.2 1.4 3.3 2 0 0 2 2 2 0 Dam-replacing HTH domain Phage_holin_6_1 PF09682.10 EAX96124.1 - 0.00055 20.3 4.2 0.0011 19.3 4.2 1.5 1 0 0 1 1 1 1 Bacteriophage holin of superfamily 6 (Holin_LLH) FtsH_ext PF06480.15 EAX96124.1 - 0.004 17.5 1.0 0.01 16.2 1.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular Sigma_reg_N PF13800.6 EAX96124.1 - 0.0075 16.5 0.4 0.023 15.0 0.4 1.8 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DUF3139 PF11337.8 EAX96124.1 - 0.017 15.7 5.6 0.048 14.3 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) EphA2_TM PF14575.6 EAX96124.1 - 0.036 14.9 1.6 0.089 13.7 1.6 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.6 EAX96124.1 - 0.053 13.5 2.2 0.092 12.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ECSCR PF15820.5 EAX96124.1 - 0.13 12.1 4.7 0.2 11.5 3.9 1.8 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Baculo_11_kDa PF06143.11 EAX96124.1 - 0.52 9.9 4.4 0.41 10.3 1.6 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF4307 PF14155.6 EAX96124.1 - 0.57 10.0 1.7 1 9.2 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) OAD_gamma PF04277.13 EAX96124.1 - 0.83 10.3 5.4 0.2 12.3 1.2 2.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4834 PF16118.5 EAX96124.1 - 3.4 8.7 12.8 0.053 14.5 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) FeoB_associated PF12669.7 EAX96124.1 - 9.7 6.7 6.9 24 5.5 6.9 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Guanylate_cyc PF00211.20 EAX96126.1 - 4.9e-41 140.4 0.0 9.5e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX96126.1 - 4.3e-13 49.4 2.1 1.3e-12 47.9 0.9 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAX96126.1 - 8.2e-06 26.0 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX96126.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated PAS PF00989.25 EAX96126.1 - 0.03 14.3 0.1 0.083 12.9 0.1 1.8 1 0 0 1 1 1 0 PAS fold TraQ PF09679.10 EAX96126.1 - 0.9 9.5 4.3 5.1 7.1 4.3 2.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Pkinase PF00069.25 EAX96129.1 - 4.2e-58 196.8 0.0 5e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96129.1 - 1.7e-25 89.8 0.0 1.4e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96129.1 - 7e-06 25.6 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX96129.1 - 0.0038 16.0 0.0 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EAX96129.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EAX96129.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family FTA2 PF13095.6 EAX96129.1 - 0.1 12.2 0.1 0.5 10.0 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UCR_TM PF02921.14 EAX96129.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Kdo PF06293.14 EAX96129.1 - 0.16 11.3 0.3 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Topo_Zn_Ribbon PF08272.11 EAX96129.1 - 0.29 10.8 1.0 0.56 9.9 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Gly-zipper_Omp PF13488.6 EAX96130.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX96130.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX96130.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4795 PF16043.5 EAX96131.1 - 0.0029 17.2 22.3 0.12 11.9 0.9 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4795) SEP PF08059.13 EAX96131.1 - 0.063 13.8 3.0 0.54 10.9 0.4 3.0 2 1 1 3 3 3 0 SEP domain DUF2344 PF10105.9 EAX96131.1 - 0.69 9.7 3.5 3.8 7.3 2.5 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF809 PF05663.11 EAX96131.1 - 2.9 8.1 8.2 16 5.6 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF809) PTR PF12789.7 EAX96131.1 - 3.9 7.6 16.5 0.16 12.1 1.7 5.2 4 1 1 5 5 5 0 Phage tail repeat like Thioredoxin PF00085.20 EAX96132.1 - 1.7e-16 60.1 0.0 3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX96132.1 - 0.0026 18.1 0.1 2.1 8.8 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EAX96132.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EAX96132.1 - 0.019 14.9 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 EAX96132.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 EAX96132.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EAX96132.1 - 0.16 12.5 0.4 2.3 8.7 0.4 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain Myb_DNA-binding PF00249.31 EAX96133.1 - 9.1e-33 112.2 4.4 2.6e-16 59.5 0.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96133.1 - 7.3e-25 87.0 1.3 1.5e-16 60.4 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96133.1 - 1.7e-05 24.6 0.5 0.24 11.3 0.1 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX96133.1 - 5e-05 23.3 0.1 0.25 11.4 0.0 2.6 1 1 1 2 2 2 2 SLIDE SAGA-Tad1 PF12767.7 EAX96133.1 - 0.0092 15.7 2.9 0.032 14.0 2.9 1.8 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF722 PF05263.11 EAX96133.1 - 0.012 15.8 0.9 0.038 14.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF722) Tox-GHH PF15636.6 EAX96133.1 - 0.054 13.5 1.6 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Myb_DNA-bind_4 PF13837.6 EAX96133.1 - 0.084 13.3 8.3 5.1 7.5 0.2 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain CBM65_1 PF18259.1 EAX96133.1 - 0.12 12.6 0.2 0.26 11.5 0.3 1.7 1 1 0 1 1 1 0 Carbohydrate binding module 65 domain 1 DUF4085 PF13315.6 EAX96133.1 - 0.12 12.0 1.5 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Rap1_C PF11626.8 EAX96133.1 - 0.17 12.0 0.9 0.96 9.6 0.9 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SH3BP5 PF05276.14 EAX96133.1 - 3.3 7.5 6.5 7.2 6.3 0.6 2.5 2 2 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) LRR_5 PF13306.6 EAX96135.1 - 3.6e-55 185.4 41.6 3.4e-24 85.3 9.0 4.5 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96135.1 - 0.0039 16.9 0.1 0.0039 16.9 0.1 5.1 5 2 0 5 5 5 1 Leucine rich repeat AP4E_app_platf PF14807.6 EAX96135.1 - 0.012 16.0 0.1 1.6 9.1 0.1 2.8 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform LRR_5 PF13306.6 EAX96136.1 - 8.1e-30 103.4 39.4 2.5e-19 69.5 19.3 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96136.1 - 2e-06 27.5 4.8 0.009 15.8 0.3 4.4 2 2 3 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 EAX96138.1 - 3.1e-37 127.4 31.5 9e-25 87.1 14.3 1.8 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96138.1 - 3.3e-08 33.2 0.8 0.00029 20.6 0.1 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EAX96138.1 - 0.16 12.4 2.8 0.82 10.2 2.2 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) HSP70 PF00012.20 EAX96140.1 - 2.9e-16 58.8 10.0 4.6e-09 35.0 0.1 3.1 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EAX96140.1 - 3e-05 23.0 0.0 0.035 12.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.8 EAX96140.1 - 0.0052 15.9 0.4 0.012 14.6 0.4 1.6 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 EAX96140.1 - 0.013 15.9 0.7 0.55 10.7 0.7 2.9 1 1 0 1 1 1 0 Cell division protein FtsA FGGY_C PF02782.16 EAX96140.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FliT PF05400.13 EAX96141.1 - 0.013 16.3 0.1 0.17 12.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DUF4205 PF13898.6 EAX96141.1 - 0.034 13.1 0.2 0.046 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) HV_small_capsid PF17086.5 EAX96141.1 - 0.052 13.8 0.1 0.089 13.1 0.1 1.4 1 0 0 1 1 1 0 Small capsid protein of Herpesviridae Vasculin PF15337.6 EAX96141.1 - 0.23 12.3 2.8 5.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 Metallophos PF00149.28 EAX96143.1 - 2.6e-27 96.7 0.0 3.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX96143.1 - 0.0093 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mlf1IP PF10248.9 EAX96144.1 - 1.8e-05 24.8 5.9 3e-05 24.1 5.9 1.4 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein EF-hand_7 PF13499.6 EAX96145.1 - 3e-18 66.0 10.4 3.6e-08 33.7 1.5 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAX96145.1 - 5.3e-17 60.2 7.6 3.7e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EAX96145.1 - 6.3e-16 56.7 15.8 6.4e-05 22.2 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EAX96145.1 - 6.5e-14 50.7 16.9 1.4e-05 24.4 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAX96145.1 - 1.5e-09 37.5 12.5 0.00017 21.3 0.4 4.0 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAX96145.1 - 0.026 14.9 0.5 0.34 11.3 0.1 2.6 1 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EAX96145.1 - 0.089 12.7 2.6 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 EAX96145.1 - 0.17 11.8 4.0 1.5 8.8 0.1 3.3 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Metallophos PF00149.28 EAX96146.1 - 1.1e-10 42.4 0.6 3.7e-10 40.7 0.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Borrelia_orfD PF02999.14 EAX96146.1 - 0.042 14.2 0.5 0.17 12.2 0.5 2.1 1 0 0 1 1 1 0 Borrelia orf-D family Gly_rich PF12810.7 EAX96148.1 - 3.4e-23 82.8 17.6 6.3e-23 81.9 17.6 1.4 1 1 0 1 1 1 1 Glycine rich protein eIF-5_eIF-2B PF01873.17 EAX96149.1 - 0.012 15.5 0.2 0.037 13.9 0.2 1.8 1 0 0 1 1 1 0 Domain found in IF2B/IF5 SPA PF08616.10 EAX96149.1 - 0.015 15.2 0.0 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 Stabilization of polarity axis PSP PF04046.16 EAX96150.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96151.1 - 0.037 14.6 4.1 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX96153.1 - 5.4e-27 93.6 12.3 5.4e-27 93.6 12.3 4.0 6 0 0 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAX96153.1 - 0.091 12.5 0.1 0.4 10.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX96154.1 - 1.6e-157 522.2 12.3 2e-157 521.9 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX96154.1 - 0.066 13.5 0.4 2.1 8.7 0.0 3.2 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAX96154.1 - 0.42 11.1 5.6 2 8.9 0.4 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX96154.1 - 0.78 10.1 5.1 9.2 6.6 0.1 3.8 4 1 0 4 4 4 0 Tup N-terminal PSP PF04046.16 EAX96156.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Guanylate_cyc PF00211.20 EAX96158.1 - 1.6e-43 148.5 0.1 2.3e-43 147.9 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX96158.1 - 2.7e-05 24.4 0.2 0.00012 22.2 0.1 2.2 3 0 0 3 3 3 1 PAS domain HNOBA PF07701.14 EAX96158.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated BAR PF03114.18 EAX96160.1 - 6.7e-07 29.2 1.7 8.6e-07 28.8 1.7 1.1 1 0 0 1 1 1 1 BAR domain Laminin_II PF06009.12 EAX96160.1 - 0.033 14.2 0.0 0.099 12.7 0.0 1.8 1 1 0 1 1 1 0 Laminin Domain II Peptidase_S8 PF00082.22 EAX96161.1 - 1.4e-09 37.6 1.1 2.9e-09 36.6 1.1 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAX96161.1 - 0.00056 19.9 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain Bac_rhamnosid_C PF17390.2 EAX96161.1 - 0.0031 17.3 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF4998 PF16389.5 EAX96161.1 - 0.0077 15.8 4.9 0.025 14.1 3.0 2.5 2 1 1 3 3 3 1 Domain of unknown function RRM_1 PF00076.22 EAX96162.1 - 1.4e-54 181.8 11.4 1.4e-14 53.6 0.0 7.3 7 0 0 7 7 7 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX96162.1 - 1.7e-07 31.1 0.3 0.044 13.8 0.0 5.0 6 0 0 6 6 6 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EAX96162.1 - 1.7e-06 28.1 0.0 0.17 12.1 0.0 3.2 3 0 0 3 3 3 2 RRM-like domain RRM_3 PF08777.11 EAX96162.1 - 1.1e-05 25.4 0.7 2.5 8.2 0.0 5.5 7 0 0 7 7 7 2 RNA binding motif RRM_occluded PF16842.5 EAX96162.1 - 3.9e-05 23.4 0.0 0.025 14.4 0.0 4.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EAX96162.1 - 0.0003 20.4 0.8 2.7 7.6 0.0 4.4 5 1 1 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX96162.1 - 0.0041 17.2 0.0 20 5.4 0.0 4.2 4 0 0 4 4 4 0 RNA recognition motif DNA_pol3_chi PF04364.13 EAX96162.1 - 0.049 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC SET_assoc PF11767.8 EAX96162.1 - 0.49 10.1 3.9 1.2 8.8 0.1 3.5 5 0 0 5 5 5 0 Histone lysine methyltransferase SET associated PHD PF00628.29 EAX96163.1 - 1.3e-12 47.4 32.6 4.1e-10 39.4 6.0 3.1 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 EAX96163.1 - 2.1e-07 30.4 15.9 6.6e-05 22.4 1.3 2.6 2 0 0 2 2 2 2 PHD-finger DUF5476 PF17570.2 EAX96163.1 - 0.034 14.5 2.9 4.7 7.7 0.2 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF5476) Presenilin PF01080.17 EAX96163.1 - 0.2 10.4 3.8 0.31 9.8 3.8 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EAX96163.1 - 1.4 7.6 10.2 2.8 6.7 10.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lar_restr_allev PF14354.6 EAX96163.1 - 4.9 7.6 13.4 0.76 10.2 7.5 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar C1_1 PF00130.22 EAX96163.1 - 7.3 6.6 26.2 0.96 9.4 1.7 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GEMIN8 PF15348.6 EAX96163.1 - 8.1 6.7 11.8 24 5.1 9.8 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Menin PF05053.13 EAX96163.1 - 9.1 4.5 5.9 13 4.0 5.9 1.1 1 0 0 1 1 1 0 Menin DUF2960 PF11173.8 EAX96164.1 - 0.036 14.5 0.3 0.089 13.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) WRKY PF03106.15 EAX96165.1 - 0.016 15.4 3.6 0.04 14.2 1.1 2.6 1 1 1 2 2 2 0 WRKY DNA -binding domain Stn1_C PF12659.7 EAX96166.1 - 0.064 13.2 0.8 0.23 11.4 0.5 2.0 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Pkinase PF00069.25 EAX96167.1 - 3.8e-60 203.5 0.0 2e-59 201.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96167.1 - 1.3e-59 201.6 0.0 3.1e-59 200.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96167.1 - 0.0003 20.2 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX96167.1 - 0.004 16.5 0.1 0.0076 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX96167.1 - 0.0077 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX96167.1 - 0.03 13.1 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RICTOR_M PF14666.6 EAX96167.1 - 0.04 13.7 2.0 0.21 11.4 0.1 3.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Pox_A32 PF04665.12 EAX96168.1 - 0.00015 21.3 2.5 0.00028 20.4 2.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX96168.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX96168.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX96168.1 - 0.054 12.7 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4107 PF13389.6 EAX96169.1 - 2.2e-73 245.8 3.9 2.6e-73 245.5 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX96169.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX96170.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX96172.1 - 4.9e-154 510.8 12.5 6.6e-154 510.3 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX96172.1 - 0.03 14.6 0.9 15 6.0 0.0 3.6 3 0 0 3 3 3 0 Tup N-terminal DUF2408 PF10303.9 EAX96172.1 - 0.36 11.4 5.7 0.2 12.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX96172.1 - 1.4 9.4 6.4 2.6 8.5 0.1 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX96174.1 - 4.2e-07 30.5 0.3 8.3e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain DNA_pol_B_2 PF03175.13 EAX96175.1 - 1.6e-16 60.2 2.6 2e-16 59.9 2.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAX96177.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain tRNA_bind PF01588.20 EAX96178.1 - 5.3e-29 100.2 0.0 7.9e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Ras PF00071.22 EAX96179.1 - 2.3e-50 170.4 0.2 2.6e-50 170.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96179.1 - 6.4e-32 110.3 0.1 9.3e-32 109.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96179.1 - 6.1e-12 45.3 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX96179.1 - 7.7e-06 26.0 0.2 2.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX96179.1 - 0.00012 21.6 0.4 0.0013 18.3 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX96179.1 - 0.00026 20.4 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX96179.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3823_C PF18003.1 EAX96179.1 - 0.09 13.5 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Asparaginase_C PF17763.1 EAX96179.1 - 0.13 12.4 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Myb_DNA-binding PF00249.31 EAX96180.1 - 1.7e-26 92.2 5.8 5.6e-13 48.9 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96180.1 - 5.2e-22 77.9 7.2 2.1e-13 50.3 2.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96180.1 - 5.1e-06 26.3 0.1 5.1e-06 26.3 0.1 2.2 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX96180.1 - 5.4e-05 23.5 12.7 0.057 13.8 2.5 3.3 2 2 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX96180.1 - 0.00016 22.0 5.7 0.11 12.9 0.8 2.6 2 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EAX96180.1 - 0.00055 19.9 2.3 0.028 14.5 0.3 2.6 1 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EAX96180.1 - 0.0035 17.5 0.6 0.009 16.2 0.4 1.9 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 E2F_TDP PF02319.20 EAX96181.1 - 1.6e-11 44.1 0.0 5.8e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF1359 PF07097.11 EAX96181.1 - 0.034 14.4 0.3 0.088 13.1 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1359) LRR_5 PF13306.6 EAX96182.1 - 2.4e-167 548.1 76.4 1.5e-26 92.8 0.2 6.7 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96182.1 - 7e-15 54.5 10.0 0.32 10.8 0.0 10.7 6 2 5 12 12 12 5 Leucine rich repeat DUF3951 PF13131.6 EAX96182.1 - 0.017 15.3 0.8 0.068 13.4 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF2621 PF11084.8 EAX96182.1 - 0.057 13.4 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) MitoNEET_N PF10660.9 EAX96182.1 - 0.16 12.0 1.2 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus MatE PF01554.18 EAX96183.1 - 0.00042 20.0 1.3 0.00042 20.0 1.3 1.9 2 1 0 2 2 2 1 MatE MatE PF01554.18 EAX96185.1 - 2.6e-20 72.7 19.9 4.5e-16 58.9 5.9 2.9 4 0 0 4 4 4 2 MatE Atthog PF18800.1 EAX96185.1 - 0.0069 16.3 4.7 0.016 15.1 0.1 2.8 1 1 0 2 2 2 1 Attenuator of Hedgehog DUF4175 PF13779.6 EAX96186.1 - 3.1 5.6 11.2 3.3 5.5 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Metal_resist PF13801.6 EAX96186.1 - 7.9 6.7 7.6 21 5.3 7.6 1.9 1 1 0 1 1 1 0 Heavy-metal resistance C2 PF00168.30 EAX96187.1 - 2.2e-21 76.1 0.0 2.3e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 EAX96188.1 - 4.9e-23 81.4 0.0 8.2e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain PTEN_C2 PF10409.9 EAX96188.1 - 0.14 11.9 0.6 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein NitrOD5 PF11537.8 EAX96189.1 - 0.038 14.1 0.0 0.05 13.8 0.0 1.1 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 Pkinase PF00069.25 EAX96189.1 - 0.089 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EAX96190.1 - 4e-10 39.5 1.5 2.2e-09 37.1 1.1 1.9 1 1 1 2 2 2 1 Protein kinase domain DNA_pol3_theta PF06440.11 EAX96190.1 - 0.031 13.9 0.3 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase III, theta subunit SCF PF02404.15 EAX96190.1 - 0.088 12.1 3.7 0.98 8.7 0.1 2.3 1 1 1 2 2 2 0 Stem cell factor Pkinase PF00069.25 EAX96191.1 - 1.3e-48 165.7 0.1 1.7e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96191.1 - 6.2e-23 81.4 0.0 2.4e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAX96191.1 - 0.00058 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAX96191.1 - 0.0016 17.8 0.2 0.0029 17.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX96191.1 - 0.0028 17.6 0.1 0.0075 16.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX96191.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_10 PF13673.7 EAX96192.1 - 6.6e-11 42.2 0.0 7.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAX96192.1 - 2e-10 40.9 0.0 2.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAX96192.1 - 7.2e-10 39.1 0.1 8.5e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EAX96192.1 - 0.00015 21.9 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EAX96192.1 - 0.0022 18.1 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAX96192.1 - 0.003 17.7 0.0 0.0036 17.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EAX96192.1 - 0.0041 16.6 0.2 0.0067 15.9 0.2 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 EAX96192.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ SapB_2 PF03489.17 EAX96193.1 - 1e-37 127.9 50.1 2.1e-10 40.5 3.2 7.9 9 0 0 9 9 9 5 Saposin-like type B, region 2 SapB_1 PF05184.15 EAX96193.1 - 2.9e-37 126.2 51.4 6.5e-09 35.6 1.7 9.0 9 0 0 9 9 9 6 Saposin-like type B, region 1 CENP-B_N PF04218.13 EAX96193.1 - 0.0018 17.8 0.2 2.6 7.7 0.0 3.0 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain ATP-synt_E_2 PF08112.11 EAX96193.1 - 0.011 16.0 1.4 17 5.8 0.0 3.9 3 0 0 3 3 3 0 ATP synthase epsilon subunit zf-C4_ClpX PF06689.13 EAX96193.1 - 0.013 15.4 14.2 2.4 8.1 0.1 5.2 4 0 0 4 4 4 0 ClpX C4-type zinc finger FAM60A PF15396.6 EAX96193.1 - 0.1 12.6 6.9 0.92 9.5 0.1 3.6 4 0 0 4 4 4 0 Protein Family FAM60A DUF2680 PF10925.8 EAX96193.1 - 0.12 12.4 0.0 21 5.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) MIF4G PF02854.19 EAX96193.1 - 0.2 11.3 2.7 2 8.0 0.1 3.1 3 1 0 3 3 3 0 MIF4G domain Cas_Csn2 PF09711.10 EAX96193.1 - 1.1 8.9 8.4 0.85 9.3 0.2 3.4 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_Csn2) SR1P PF13790.6 EAX96193.1 - 2.3 8.4 16.8 11 6.2 0.2 6.1 5 0 0 5 5 5 0 SR1 protein MatE PF01554.18 EAX96194.1 - 5.8e-35 120.3 14.5 1.4e-19 70.4 3.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EAX96194.1 - 5.2e-05 23.3 4.9 5.2e-05 23.3 4.9 3.5 3 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Ras PF00071.22 EAX96195.1 - 2.1e-37 128.2 0.1 2.5e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96195.1 - 2.9e-26 92.1 0.1 6.8e-26 90.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96195.1 - 1.7e-15 56.9 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX96195.1 - 1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX96195.1 - 1.5e-06 27.8 0.1 1.6e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX96195.1 - 3.4e-06 27.1 1.9 0.046 13.6 0.4 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX96195.1 - 3.6e-06 26.6 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX96195.1 - 1.3e-05 24.7 0.6 2.6e-05 23.8 0.1 1.7 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EAX96195.1 - 0.0014 18.4 3.1 0.0022 17.8 0.2 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EAX96195.1 - 0.0061 16.6 0.2 0.0086 16.1 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain KH_10 PF17905.1 EAX96195.1 - 0.0062 16.9 0.1 0.018 15.5 0.0 1.8 1 1 1 2 2 2 1 GLD-3 KH domain 5 G-alpha PF00503.20 EAX96195.1 - 0.0084 15.3 3.5 0.02 14.0 2.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 EAX96195.1 - 0.012 15.4 0.3 0.089 12.5 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF5356 PF17309.2 EAX96195.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5356) RLL PF10036.9 EAX96195.1 - 0.031 14.1 0.5 0.047 13.5 0.5 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein AAA_24 PF13479.6 EAX96195.1 - 0.097 12.4 0.3 0.19 11.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAX96195.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Metallophos PF00149.28 EAX96196.1 - 1.6e-10 41.9 3.0 3e-10 40.9 3.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MIG-14_Wnt-bd PF06664.12 EAX96197.1 - 1.7e-49 168.6 43.5 2.7e-49 168.0 43.5 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Pkinase PF00069.25 EAX96198.1 - 1.4e-48 165.5 0.0 1.9e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96198.1 - 6.2e-26 91.2 0.0 7.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96198.1 - 9.4e-10 38.3 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX96198.1 - 0.013 14.6 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 EAX96198.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 EAX96198.1 - 0.07 12.7 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.31 EAX96199.1 - 6.8e-19 67.8 1.8 2.2e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96199.1 - 9.1e-18 64.3 4.2 1.3e-09 38.2 1.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96199.1 - 0.00035 20.4 0.2 0.02 14.7 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Thioredoxin PF00085.20 EAX96200.1 - 1.9e-20 72.8 0.0 2.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAX96200.1 - 2.2e-09 37.4 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EAX96200.1 - 4.3e-06 27.0 0.0 1.2e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX96200.1 - 7.8e-06 26.3 0.1 8.6e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAX96200.1 - 2.6e-05 23.7 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EAX96200.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DIM1 PF02966.16 EAX96200.1 - 0.0039 17.0 0.0 0.0044 16.8 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF836 PF05768.14 EAX96200.1 - 0.0098 16.3 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 EAX96200.1 - 0.05 13.4 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 EAX96200.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EAX96200.1 - 0.071 13.3 0.2 0.15 12.3 0.2 1.5 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 EAX96200.1 - 0.14 11.9 0.3 0.38 10.4 0.3 1.8 1 1 0 1 1 1 0 Redoxin IBD PF10416.9 EAX96201.1 - 9.4e-43 145.3 2.9 9.4e-43 145.3 2.9 1.5 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD TMEM154 PF15102.6 EAX96202.1 - 4.4e-06 26.7 0.6 9.5e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 TMEM154 protein family FAM176 PF14851.6 EAX96202.1 - 6.9e-06 25.8 0.9 1.4e-05 24.8 0.9 1.5 1 0 0 1 1 1 1 FAM176 family Connexin PF00029.19 EAX96202.1 - 4e-05 23.5 0.7 6.3e-05 22.9 0.7 1.2 1 0 0 1 1 1 1 Connexin V_ATPase_I PF01496.19 EAX96202.1 - 0.0001 20.4 1.3 0.00014 20.0 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3169 PF11368.8 EAX96202.1 - 0.00012 21.6 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF4834 PF16118.5 EAX96202.1 - 0.00045 21.1 4.8 0.00069 20.5 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) Chordopox_A13L PF05961.11 EAX96202.1 - 0.0013 18.9 0.0 0.0043 17.2 0.0 1.9 1 0 0 1 1 1 1 Chordopoxvirus A13L protein TMEM51 PF15345.6 EAX96202.1 - 0.002 18.0 0.2 0.0034 17.2 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Serinc PF03348.15 EAX96202.1 - 0.0022 17.0 2.2 0.004 16.1 2.2 1.4 1 0 0 1 1 1 1 Serine incorporator (Serinc) LRR19-TM PF15176.6 EAX96202.1 - 0.0027 17.7 0.7 0.0061 16.5 0.7 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain SID-1_RNA_chan PF13965.6 EAX96202.1 - 0.0034 15.9 1.4 0.0046 15.4 1.4 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Serglycin PF04360.12 EAX96202.1 - 0.0035 17.3 6.0 0.0088 16.0 6.0 1.7 1 0 0 1 1 1 1 Serglycin Nucleoside_tran PF01733.18 EAX96202.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoside transporter SpoIIIAH PF12685.7 EAX96202.1 - 0.0047 16.8 0.5 0.0047 16.8 0.5 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein MAP17 PF15807.5 EAX96202.1 - 0.0065 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 EAX96202.1 - 0.013 16.3 0.0 0.034 15.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TRAP_alpha PF03896.16 EAX96202.1 - 0.018 14.2 5.2 0.035 13.3 5.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vpu PF00558.19 EAX96202.1 - 0.02 14.7 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Vpu protein BatD PF13584.6 EAX96202.1 - 0.021 13.7 1.5 0.035 12.9 0.0 2.0 2 1 1 3 3 3 0 Oxygen tolerance Trp_oprn_chp PF09534.10 EAX96202.1 - 0.029 14.2 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Zip PF02535.22 EAX96202.1 - 0.036 13.3 3.7 0.054 12.7 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM132D_C PF15706.5 EAX96202.1 - 0.036 13.8 2.2 0.092 12.5 1.9 1.9 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FeoB_associated PF12669.7 EAX96202.1 - 0.049 14.0 1.5 0.12 12.8 1.5 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Orf78 PF06024.12 EAX96202.1 - 0.05 13.9 0.1 0.05 13.9 0.1 2.4 1 1 1 2 2 1 0 Orf78 (ac78) Peptidase_M56 PF05569.11 EAX96202.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 RPN2_C PF18004.1 EAX96202.1 - 0.11 12.4 5.5 0.18 11.7 5.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CsrA PF02599.16 EAX96202.1 - 0.12 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Global regulator protein family NVEALA PF14055.6 EAX96202.1 - 0.13 12.3 0.4 0.52 10.3 0.4 2.0 1 0 0 1 1 1 0 NVEALA protein DUF4381 PF14316.6 EAX96202.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Presenilin PF01080.17 EAX96202.1 - 0.26 10.0 4.3 0.42 9.3 4.3 1.3 1 0 0 1 1 1 0 Presenilin CRA PF06589.11 EAX96202.1 - 0.38 10.9 5.3 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF2615 PF11027.8 EAX96202.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Period_C PF12114.8 EAX96202.1 - 0.88 9.1 10.8 0.036 13.7 4.4 1.9 2 0 0 2 2 1 0 Period protein 2/3C-terminal region TFB6 PF17110.5 EAX96202.1 - 1.1 9.0 5.3 2 8.1 5.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Syndecan PF01034.20 EAX96202.1 - 1.6 8.7 3.4 0.82 9.6 0.8 1.8 2 0 0 2 2 1 0 Syndecan domain Pox_A32 PF04665.12 EAX96203.1 - 6.9e-07 29.0 2.6 6.9e-07 29.0 2.6 1.9 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX96203.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX96203.1 - 0.00018 21.3 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX96203.1 - 0.0002 21.4 3.4 0.00046 20.2 3.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX96203.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX96203.1 - 0.0013 18.5 0.5 0.0026 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX96203.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX96203.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX96203.1 - 0.062 12.9 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX96203.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX96203.1 - 0.092 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2897 PF11446.8 EAX96204.1 - 0.42 10.5 2.5 0.99 9.3 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX96205.1 - 3e-63 212.0 6.0 3.3e-63 211.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PQ-loop PF04193.14 EAX96207.1 - 1.6e-18 66.2 16.4 1.2e-14 53.9 3.9 2.7 3 0 0 3 3 3 2 PQ loop repeat Pkinase PF00069.25 EAX96210.1 - 7.4e-53 179.6 0.0 9.2e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96210.1 - 1.1e-29 103.6 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96210.1 - 5.6e-05 22.6 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX96210.1 - 0.00034 19.5 0.0 0.00061 18.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX96210.1 - 0.0049 16.5 0.2 0.012 15.3 0.1 1.6 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 EAX96210.1 - 0.0084 15.5 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EAX96210.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_S8 PF00082.22 EAX96211.1 - 2.3e-39 135.4 1.0 3.1e-39 135.0 1.0 1.2 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 EAX96211.1 - 0.00042 20.6 14.0 0.00082 19.7 14.0 1.5 1 0 0 1 1 1 1 EGF-like domain PPC PF04151.15 EAX96211.1 - 0.023 15.8 3.7 16 6.7 0.1 4.2 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain hEGF PF12661.7 EAX96211.1 - 0.1 13.3 7.2 0.24 12.1 7.2 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EAX96211.1 - 0.17 12.0 5.9 0.35 10.9 5.9 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EAX96211.1 - 0.26 11.6 10.9 0.65 10.4 10.9 1.6 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EAX96211.1 - 1.3 9.4 8.2 2.6 8.4 8.2 1.4 1 0 0 1 1 1 0 EB module Toxin_2 PF00451.19 EAX96211.1 - 8 6.9 9.2 21 5.5 9.2 1.7 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 BRE1 PF08647.11 EAX96213.1 - 0.012 15.7 0.0 0.012 15.7 0.0 5.0 5 1 0 5 5 5 0 BRE1 E3 ubiquitin ligase DUF641 PF04859.12 EAX96213.1 - 0.059 13.7 10.8 0.41 11.0 0.2 3.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Mce4_CUP1 PF11887.8 EAX96213.1 - 0.18 11.3 2.9 1.2 8.6 0.2 2.6 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3510 PF12022.8 EAX96213.1 - 0.61 10.5 5.8 0.33 11.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Myb_DNA-bind_3 PF12776.7 EAX96213.1 - 0.67 11.0 6.5 1.9 9.5 1.4 3.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 EAX96213.1 - 1.7 9.0 9.0 19 5.6 2.0 3.6 3 0 0 3 3 3 0 Retrotransposon gag protein Enkurin PF13864.6 EAX96214.1 - 2e-21 76.2 2.0 2e-21 76.2 2.0 2.0 2 1 0 2 2 2 1 Calmodulin-binding Flg_new PF09479.10 EAX96214.1 - 0.18 12.0 0.5 0.45 10.7 0.5 1.7 1 1 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) zf-RING_4 PF14570.6 EAX96216.1 - 3.6e-16 58.7 15.6 6.9e-16 57.8 15.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EAX96216.1 - 2.6e-06 27.2 10.2 2.6e-06 27.2 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EAX96216.1 - 6.7e-05 22.6 2.2 0.0079 16.0 0.3 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_2 PF13639.6 EAX96216.1 - 0.0046 17.3 13.4 0.0046 17.3 13.4 2.0 2 0 0 2 2 2 1 Ring finger domain RRM_1 PF00076.22 EAX96216.1 - 0.0074 16.1 0.1 0.031 14.1 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX96216.1 - 0.056 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 EAX96216.1 - 0.64 9.9 12.9 1.6 8.6 12.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX96216.1 - 4.8 7.1 21.2 0.059 13.2 7.2 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EAX96216.1 - 5.1 7.3 12.7 0.33 11.1 6.7 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger NicO PF03824.16 EAX96217.1 - 4.5 6.5 7.3 4.6 6.5 7.3 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pkinase PF00069.25 EAX96218.1 - 9.5e-58 195.6 0.0 1.9e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96218.1 - 4.7e-56 190.0 0.0 1.1e-55 188.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX96218.1 - 0.026 13.3 0.2 0.026 13.3 0.2 1.9 2 0 0 2 2 2 0 Fungal protein kinase Baculo_p24 PF05073.12 EAX96218.1 - 0.027 14.2 0.1 0.19 11.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Kdo PF06293.14 EAX96218.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 EAX96219.1 - 2.8e-55 184.8 29.3 1.1e-12 48.4 0.5 9.4 5 3 3 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96219.1 - 6.3e-45 151.0 24.8 1.1e-13 51.4 0.1 13.8 7 5 8 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96219.1 - 1.6e-35 117.0 19.2 0.00053 20.2 0.0 14.3 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 EAX96219.1 - 1.8e-32 111.0 15.6 9.7e-07 29.0 0.0 9.7 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX96219.1 - 7.4e-29 98.9 22.4 0.00085 19.7 0.1 12.5 13 0 0 13 13 13 7 Ankyrin repeat Pkinase PF00069.25 EAX96220.1 - 5.7e-25 88.2 0.0 8.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96220.1 - 1.8e-13 50.4 0.0 2.7e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX96220.1 - 0.00012 21.0 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX96220.1 - 0.00041 20.3 0.0 0.0081 16.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX96220.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rax2 PF12768.7 EAX96222.1 - 0.045 13.2 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 EAX96222.1 - 0.095 12.6 0.6 0.13 12.1 0.6 1.2 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 EAX96222.1 - 0.39 10.7 3.6 0.91 9.5 3.6 1.6 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_Omp PF13488.6 EAX96223.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX96223.1 - 0.23 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX96223.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Ribonuc_2-5A PF06479.12 EAX96226.1 - 1.2e-25 90.2 0.1 2.7e-25 89.0 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A DUF4251 PF14059.6 EAX96226.1 - 0.29 11.1 7.2 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Ribosomal_S21e PF01249.18 EAX96227.1 - 2.1e-33 114.3 0.0 2.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Nit_Regul_Hom PF10126.9 EAX96229.1 - 0.0024 17.9 0.6 0.73 9.9 0.1 3.0 2 0 0 2 2 2 2 Uncharacterized protein, homolog of nitrogen regulatory protein PII Cadherin_C PF01049.17 EAX96229.1 - 3.2 8.1 6.5 6.1 7.2 0.4 3.1 4 0 0 4 4 4 0 Cadherin cytoplasmic region CEP63 PF17045.5 EAX96230.1 - 0.0039 17.1 30.7 0.0039 17.1 30.7 4.4 1 1 3 4 4 4 2 Centrosomal protein of 63 kDa Fib_alpha PF08702.10 EAX96230.1 - 0.0044 17.2 0.4 0.0044 17.2 0.4 6.7 2 1 5 7 7 7 3 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EAX96230.1 - 0.0092 16.0 6.7 0.0092 16.0 6.7 9.8 6 3 3 9 9 9 3 TATA element modulatory factor 1 DNA binding Arteri_nsp7a PF16749.5 EAX96230.1 - 0.25 11.5 3.6 0.25 11.5 0.1 2.6 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha Spc7 PF08317.11 EAX96230.1 - 0.33 9.8 89.7 0.34 9.8 20.1 4.9 2 2 1 4 4 4 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EAX96230.1 - 3 7.8 24.4 0.3 11.0 3.6 6.0 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4108 PF13390.6 EAX96231.1 - 8e-63 210.6 6.6 8.9e-63 210.5 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_22 PF13401.6 EAX96233.1 - 0.0011 19.3 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX96233.1 - 0.0012 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX96233.1 - 0.0041 17.5 0.0 0.0059 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX96233.1 - 0.0076 16.3 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAX96233.1 - 0.021 14.3 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX96233.1 - 0.051 13.1 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX96233.1 - 0.09 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAX96233.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX96234.1 - 3.5e-155 514.5 13.6 4.4e-155 514.2 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX96234.1 - 0.19 11.6 1.5 0.64 9.9 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX96234.1 - 1 9.9 8.7 3 8.4 2.8 3.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX96234.1 - 3.1 8.3 6.7 1.7 9.2 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX96236.1 - 0.029 14.8 0.4 0.061 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX96236.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX96237.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Adaptin_N PF01602.20 EAX96238.1 - 0.00015 20.4 3.6 0.00032 19.4 0.7 2.3 3 0 0 3 3 3 1 Adaptin N terminal region V-ATPase_H_N PF03224.14 EAX96238.1 - 0.016 14.5 0.6 0.044 13.1 0.5 1.8 2 1 0 2 2 2 0 V-ATPase subunit H Cnd1 PF12717.7 EAX96238.1 - 0.034 14.2 1.7 0.062 13.3 0.4 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Glyco_transf_24 PF18404.1 EAX96240.1 - 7.5e-140 464.9 1.7 1.3e-139 464.2 1.7 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EAX96240.1 - 2.9e-17 63.5 0.0 1e-16 61.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EAX96240.1 - 1.2e-12 47.9 0.0 3.4e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 EAX96240.1 - 1.4e-07 31.5 1.0 3.4e-07 30.3 0.3 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAX96240.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 LRR_5 PF13306.6 EAX96241.1 - 3.5e-36 124.0 26.0 2e-12 47.2 4.9 4.6 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96241.1 - 6.6e-07 29.0 0.2 4.9 7.0 0.0 5.6 4 3 2 6 6 6 4 Leucine rich repeat Defb50 PF17546.2 EAX96241.1 - 3 7.8 6.3 46 4.0 0.0 3.3 3 0 0 3 3 3 0 Beta defensin 50 C2-C2_1 PF11618.8 EAX96242.1 - 7.9e-06 26.0 0.5 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 PspA_IM30 PF04012.12 EAX96242.1 - 5.7e-05 22.8 9.9 5.7e-05 22.8 9.9 4.2 2 2 0 3 3 3 1 PspA/IM30 family CENP-F_leu_zip PF10473.9 EAX96242.1 - 0.002 18.1 3.3 0.002 18.1 3.3 5.5 3 2 1 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 EAX96242.1 - 0.0028 17.6 8.2 0.0028 17.6 8.2 6.8 5 1 1 6 6 6 2 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 EAX96242.1 - 0.017 15.3 8.1 0.017 15.3 8.1 5.8 3 1 1 5 5 5 0 Tropomyosin like ADIP PF11559.8 EAX96242.1 - 0.022 14.9 5.3 0.022 14.9 5.3 6.4 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EAX96242.1 - 0.029 15.0 0.1 0.029 15.0 0.1 6.8 5 1 0 5 5 5 0 SlyX DUF4250 PF14056.6 EAX96242.1 - 5.4 7.1 5.7 19 5.3 0.5 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) HIP1_clath_bdg PF16515.5 EAX96243.1 - 0.047 14.3 0.6 0.047 14.3 0.6 3.9 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cob_adeno_trans PF01923.18 EAX96243.1 - 0.17 12.0 1.6 0.46 10.6 1.6 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase MCC-bdg_PDZ PF10506.9 EAX96243.1 - 0.36 10.9 4.7 0.68 10.0 2.8 2.4 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3573 PF12097.8 EAX96243.1 - 0.38 9.5 1.2 0.57 8.9 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) COG5 PF10392.9 EAX96243.1 - 0.56 10.4 6.5 0.26 11.5 0.9 2.8 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Rotamase PF00639.21 EAX96243.1 - 2.5 9.1 9.2 2.8 8.9 0.7 2.8 2 1 0 2 2 2 0 PPIC-type PPIASE domain Syntaxin_2 PF14523.6 EAX96243.1 - 7.2 7.0 15.9 2.4 8.6 0.3 4.1 4 1 0 4 4 4 0 Syntaxin-like protein Myb_DNA-binding PF00249.31 EAX96244.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_9 PF14658.6 EAX96245.1 - 0.11 12.8 0.1 0.52 10.7 0.0 2.2 1 1 0 1 1 1 0 EF-hand domain bZIP_1 PF00170.21 EAX96245.1 - 0.27 11.4 0.1 0.27 11.4 0.1 8.0 4 3 3 8 8 8 0 bZIP transcription factor Pox_A_type_inc PF04508.12 EAX96245.1 - 0.74 9.8 11.4 12 6.0 0.3 5.4 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat CENP-H PF05837.12 EAX96245.1 - 2.1 8.8 63.1 0.38 11.2 16.7 5.0 3 2 2 5 5 5 0 Centromere protein H (CENP-H) ComGF PF15980.5 EAX96246.1 - 0.035 14.5 0.0 0.054 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative Competence protein ComGF UME PF08064.13 EAX96247.1 - 0.012 15.5 5.9 7.6 6.5 0.1 4.9 5 1 0 5 5 5 0 UME (NUC010) domain HEAT PF02985.22 EAX96247.1 - 0.054 13.8 0.0 30 5.2 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat DUF3437 PF11919.8 EAX96247.1 - 0.055 13.4 0.1 0.83 9.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) BP28CT PF08146.12 EAX96247.1 - 0.067 13.0 0.2 8.2 6.2 0.0 3.0 2 0 0 2 2 2 0 BP28CT (NUC211) domain Vac14_Fab1_bd PF12755.7 EAX96247.1 - 0.07 13.7 7.3 7.5 7.2 0.0 5.8 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region Bcl-2 PF00452.19 EAX96247.1 - 0.23 12.2 0.3 30 5.4 0.0 3.6 3 1 1 4 4 4 0 Apoptosis regulator proteins, Bcl-2 family Nod1 PF17114.5 EAX96247.1 - 0.24 11.5 6.8 0.058 13.6 0.7 3.0 3 1 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 FANCI_S2 PF14676.6 EAX96247.1 - 2.2 8.5 9.9 20 5.5 0.2 4.9 4 3 1 5 5 5 0 FANCI solenoid 2 Ank_2 PF12796.7 EAX96248.1 - 6.2e-36 122.9 22.9 2e-13 50.7 2.5 5.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96248.1 - 4.7e-30 103.6 11.1 3.1e-07 30.8 0.1 7.9 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX96248.1 - 6.6e-26 89.6 16.4 1.7e-05 25.0 0.1 9.8 9 2 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 EAX96248.1 - 1.7e-25 86.3 13.7 0.00094 19.5 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat DUF3447 PF11929.8 EAX96248.1 - 3.2e-25 87.9 1.4 3.2e-25 87.9 1.4 4.6 4 0 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX96248.1 - 3.1e-21 75.1 13.0 1.2e-06 28.7 0.2 6.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96249.1 - 6.7e-19 67.6 6.8 6.7e-19 67.6 6.8 4.8 3 2 1 5 5 5 3 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96249.1 - 2.9e-11 43.8 0.4 1.2e-09 38.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96249.1 - 1.6e-09 38.1 3.4 1.7e-05 25.2 0.5 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96249.1 - 1.6e-06 28.0 2.5 0.013 15.9 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX96249.1 - 4.8e-05 23.6 2.6 0.0018 18.5 0.3 3.5 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX96249.1 - 0.0086 16.5 0.8 0.1 13.1 0.2 2.9 3 0 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 EAX96250.1 - 3.3e-34 116.7 3.3 3.3e-34 116.7 3.3 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96250.1 - 2.5e-27 95.3 2.2 2.4e-12 47.3 0.3 4.3 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96250.1 - 8.6e-25 86.0 2.8 2.5e-08 34.0 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX96250.1 - 3.2e-23 81.5 1.7 6.6e-13 48.6 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX96250.1 - 9.9e-23 80.2 6.4 4.2e-06 27.2 0.1 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96250.1 - 1.4e-18 65.1 3.5 4.2e-05 23.6 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat SLC35F PF06027.12 EAX96251.1 - 3e-35 122.2 28.1 4.2e-35 121.7 28.1 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX96251.1 - 1.3e-11 44.9 41.3 1.3e-05 25.4 11.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family LRR19-TM PF15176.6 EAX96251.1 - 3.8 7.5 7.8 6.6 6.8 0.0 3.4 3 1 1 4 4 4 0 Leucine-rich repeat family 19 TM domain DUF4131 PF13567.6 EAX96251.1 - 4.8 6.8 14.5 13 5.4 0.7 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) HydF_tetramer PF18133.1 EAX96252.1 - 5.9e-42 142.1 0.0 1.1e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Hydrogen maturase F tetramerization domain MMR_HSR1 PF01926.23 EAX96252.1 - 7.7e-22 77.5 1.7 2e-19 69.7 0.2 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase HydF_dimer PF18128.1 EAX96252.1 - 9.4e-13 48.1 1.7 1.7e-11 44.1 0.0 3.3 3 1 0 3 3 3 1 Hydrogen maturase F dimerization domain FeoB_N PF02421.18 EAX96252.1 - 6.2e-09 35.6 0.9 1.1e-08 34.8 0.9 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAX96252.1 - 5e-06 26.7 3.7 0.0014 18.7 0.1 3.5 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 EAX96252.1 - 0.00055 19.5 4.5 0.062 12.8 2.6 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Nuc_deoxyri_tr2 PF15891.5 EAX96252.1 - 0.01 16.1 0.2 2.9 8.3 0.0 2.4 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Arf PF00025.21 EAX96252.1 - 0.024 14.1 0.7 0.084 12.3 0.7 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family Oxidored_nitro PF00148.19 EAX96252.1 - 0.051 12.3 0.1 0.34 9.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase cobW PF02492.19 EAX96252.1 - 0.12 12.0 1.8 19 4.8 0.0 3.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EAX96252.1 - 0.15 12.3 0.4 0.71 10.1 0.0 2.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EAX96252.1 - 0.19 12.2 1.0 0.86 10.1 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF4127 PF13552.6 EAX96252.1 - 0.2 10.2 0.6 0.49 8.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) RsgA_GTPase PF03193.16 EAX96252.1 - 0.2 11.6 5.1 0.86 9.5 0.2 2.4 1 1 1 2 2 2 0 RsgA GTPase ParB PF08775.10 EAX96252.1 - 0.48 10.9 3.0 3.7 8.0 2.4 2.3 2 0 0 2 2 2 0 ParB family zf-RING_7 PF02591.15 EAX96252.1 - 4 7.7 5.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain tRNA-synt_2 PF00152.20 EAX96253.1 - 8e-34 117.1 0.0 9.4e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Pedibin PF08182.11 EAX96253.1 - 0.015 15.0 3.5 0.041 13.7 3.5 1.7 1 0 0 1 1 1 0 Pedibin/Hym-346 family Diacid_rec PF05651.13 EAX96253.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition Vps16_N PF04841.13 EAX96254.1 - 0.0029 16.4 0.4 0.0052 15.6 0.1 1.5 2 0 0 2 2 2 1 Vps16, N-terminal region Ank_2 PF12796.7 EAX96255.1 - 9e-20 71.1 3.4 2.2e-13 50.6 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96255.1 - 2.7e-14 53.3 0.1 1.9e-06 28.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96255.1 - 4.1e-14 52.5 0.2 5.9e-09 36.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96255.1 - 2.1e-13 49.1 0.2 0.00026 21.2 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX96255.1 - 4e-06 27.0 0.0 0.00079 19.8 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EAX96256.1 - 1.5e-86 285.0 54.0 6.4e-16 58.7 0.6 9.2 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96256.1 - 4.9e-69 227.9 29.4 5.8e-11 42.7 0.1 15.2 7 3 8 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96256.1 - 4.9e-58 192.4 19.8 7e-10 39.0 0.0 11.5 5 2 5 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX96256.1 - 5.8e-51 168.8 27.1 1.1e-05 25.6 0.0 16.1 16 0 0 16 16 16 11 Ankyrin repeat Ank_3 PF13606.6 EAX96256.1 - 3.9e-50 162.0 33.4 3.7e-05 23.8 0.1 17.7 19 0 0 19 19 19 10 Ankyrin repeat DUF3447 PF11929.8 EAX96256.1 - 2e-33 114.2 4.9 2e-33 114.2 4.9 6.6 3 1 4 7 7 7 1 Domain of unknown function (DUF3447) IreB PF06135.12 EAX96256.1 - 0.11 12.7 1.6 0.37 11.0 1.6 2.0 1 0 0 1 1 1 0 IreB regulatory phosphoprotein CAP_N PF01213.19 EAX96256.1 - 0.92 8.9 2.5 4.6 6.6 0.7 2.3 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Copine PF07002.16 EAX96257.1 - 9.6e-27 93.9 0.0 2.5e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Copine CASP_C PF08172.12 EAX96259.1 - 0.00087 18.7 0.4 0.0011 18.4 0.4 1.2 1 0 0 1 1 1 1 CASP C terminal TSC22 PF01166.18 EAX96259.1 - 0.00095 19.4 0.1 0.0019 18.5 0.1 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EAX96259.1 - 0.0034 17.4 1.0 0.0057 16.7 1.0 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EAX96259.1 - 0.0042 17.3 0.6 0.0052 17.0 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RTBV_P46 PF06216.11 EAX96259.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.0 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein SlyX PF04102.12 EAX96259.1 - 0.012 16.2 0.7 0.012 16.2 0.7 1.6 2 0 0 2 2 2 0 SlyX TolA_bind_tri PF16331.5 EAX96259.1 - 0.013 15.6 1.2 0.027 14.5 1.2 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation HMMR_C PF15908.5 EAX96259.1 - 0.014 15.7 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 EAX96259.1 - 0.026 14.6 0.5 0.06 13.5 0.5 1.6 1 1 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 EAX96259.1 - 0.033 14.1 0.8 0.061 13.2 0.8 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4482 PF14818.6 EAX96259.1 - 0.056 14.3 0.1 0.081 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Cnn_1N PF07989.11 EAX96259.1 - 0.073 13.2 0.5 0.22 11.7 0.5 1.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EAX96259.1 - 0.58 10.0 3.4 0.2 11.4 0.6 1.7 2 0 0 2 2 2 0 Septum formation initiator Big_8 PF17961.1 EAX96260.1 - 0.024 14.7 0.3 0.06 13.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig domain B3R PF17057.5 EAX96260.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxviridae B3 protein SH3_5 PF08460.10 EAX96260.1 - 0.059 13.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain DUF3839 PF12943.7 EAX96261.1 - 2.7e-157 521.5 11.1 3.4e-157 521.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX96261.1 - 0.11 12.9 0.3 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX96261.1 - 0.14 12.0 0.6 0.5 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase TMP PF05017.14 EAX96263.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96264.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4108 PF13390.6 EAX96265.1 - 5.2e-56 188.6 4.1 5.8e-56 188.4 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX96267.1 - 3.6e-07 29.9 2.7 3.6e-07 29.9 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX96267.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX96267.1 - 0.00016 21.7 3.0 0.00037 20.5 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX96267.1 - 0.00023 20.9 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX96267.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX96267.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX96267.1 - 0.0013 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX96267.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX96267.1 - 0.068 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX96267.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX96267.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KilA-N PF04383.13 EAX96268.1 - 1.3e-40 137.7 0.6 2.6e-40 136.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX96269.1 - 1.1e-06 29.2 0.1 2.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX96269.1 - 0.02 14.7 2.0 0.078 12.8 0.5 2.4 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX96270.1 - 9.6e-155 513.1 14.4 1.2e-154 512.7 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96270.1 - 0.067 13.6 1.8 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX96270.1 - 0.071 13.5 0.6 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX96270.1 - 0.28 11.7 7.0 3.1 8.3 0.5 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX96270.1 - 2.6 8.4 6.1 13 6.1 0.1 3.7 3 2 1 4 4 4 0 Tup N-terminal AbiJ_NTD5 PF18865.1 EAX96274.1 - 0.0061 16.3 0.6 2.1 8.2 0.0 3.7 2 1 1 3 3 3 2 AbiJ N-terminal domain 5 DUF563 PF04577.14 EAX96276.1 - 1.1e-30 107.4 0.1 3.1e-30 105.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) SGS PF05002.15 EAX96277.1 - 1.4e-19 70.0 2.1 3.3e-19 68.8 2.0 1.9 1 1 1 2 2 2 1 SGS domain CS PF04969.16 EAX96277.1 - 8.4e-05 23.5 1.9 0.00015 22.7 1.9 1.4 1 0 0 1 1 1 1 CS domain E3_UFM1_ligase PF09743.9 EAX96277.1 - 0.0043 16.7 0.1 0.0061 16.2 0.1 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Vac14_Fab1_bd PF12755.7 EAX96278.1 - 0.031 14.9 2.8 0.077 13.6 0.1 3.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region 23S_rRNA_IVP PF05635.11 EAX96278.1 - 0.32 11.3 4.1 0.29 11.5 0.2 2.9 3 0 0 3 3 3 0 23S rRNA-intervening sequence protein DPM3 PF08285.11 EAX96279.1 - 0.003 17.7 0.2 0.0038 17.4 0.2 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) 2TM PF13239.6 EAX96279.1 - 0.015 15.6 0.2 0.019 15.2 0.2 1.2 1 0 0 1 1 1 0 2TM domain SdpI PF13630.6 EAX96279.1 - 0.075 13.2 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family Pkinase PF00069.25 EAX96280.1 - 1.7e-61 207.9 0.0 2.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96280.1 - 1.3e-27 96.7 0.0 1.8e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX96280.1 - 0.0019 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX96280.1 - 0.013 15.1 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MarR_2 PF12802.7 EAX96280.1 - 0.19 11.6 0.0 0.59 10.1 0.0 1.9 1 1 0 1 1 1 0 MarR family CTD PF12815.7 EAX96283.1 - 1.2e-07 32.2 15.4 0.047 14.3 3.0 3.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Keratin_B2_2 PF13885.6 EAX96283.1 - 0.19 11.7 45.5 1.7 8.7 10.6 5.2 1 1 1 3 3 3 0 Keratin, high sulfur B2 protein RNase_3_N PF18497.1 EAX96284.1 - 0.014 15.7 0.9 0.071 13.3 0.1 2.3 1 1 2 3 3 3 0 Ribonuclease III N-terminal domain DUF1748 PF08520.10 EAX96285.1 - 0.039 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) LRR_5 PF13306.6 EAX96286.1 - 1.2e-89 296.9 89.9 2.5e-18 66.3 4.6 6.3 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96286.1 - 2.8e-17 62.2 13.1 8.3e-05 22.3 0.2 9.4 5 2 7 12 12 12 7 Leucine rich repeat LRR_4 PF12799.7 EAX96286.1 - 0.009 16.4 19.7 1.6 9.3 0.4 7.6 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) Pecanex_C PF05041.15 EAX96288.1 - 4.2e-27 95.2 0.6 9.1e-27 94.1 0.6 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) CobD_Cbib PF03186.13 EAX96288.1 - 3.6 6.7 6.2 0.32 10.2 0.8 1.9 2 0 0 2 2 2 0 CobD/Cbib protein Metallophos PF00149.28 EAX96289.1 - 3.9e-32 112.4 0.3 4.8e-32 112.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAX96289.1 - 1.8e-14 53.9 1.5 3e-14 53.2 1.5 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAX96289.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAX96290.1 - 2.9e-36 125.9 0.0 3.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX96290.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain E2F_TDP PF02319.20 EAX96293.1 - 1.3e-12 47.6 0.0 2.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Ank_2 PF12796.7 EAX96294.1 - 5.6e-27 94.1 2.8 3.2e-14 53.3 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96294.1 - 4.1e-13 49.3 0.3 1.2e-06 28.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX96294.1 - 1.7e-11 44.4 0.1 9.1e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX96294.1 - 2.2e-10 40.5 0.0 6.2e-06 26.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX96294.1 - 1.4e-08 34.3 0.0 0.00051 20.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat CENP-N PF05238.13 EAX96294.1 - 0.0067 15.8 1.0 0.0081 15.5 1.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Bromodomain PF00439.25 EAX96297.1 - 5.8e-22 77.6 0.0 1.9e-21 75.9 0.0 1.8 1 1 1 2 2 2 1 Bromodomain ThiF PF00899.21 EAX96298.1 - 0.13 11.6 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 ThiF family Ank_2 PF12796.7 EAX96300.1 - 2.8e-18 66.3 1.0 7.9e-11 42.4 0.2 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96300.1 - 6.1e-13 47.7 5.2 0.082 13.5 0.0 6.9 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAX96300.1 - 1.7e-12 47.6 3.7 0.00013 22.5 0.1 5.1 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96300.1 - 1.1e-08 35.1 2.7 0.61 10.5 0.3 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX96300.1 - 0.14 12.7 2.9 48 4.6 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat LRR_5 PF13306.6 EAX96301.1 - 6.5e-71 236.3 42.0 2.7e-24 85.5 3.7 4.7 2 2 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96301.1 - 8.8e-12 44.6 3.7 0.042 13.6 0.0 7.0 6 2 3 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 EAX96301.1 - 5.6e-05 23.4 2.6 0.073 13.5 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX96302.1 - 4.1e-12 46.2 5.7 6.5e-12 45.5 5.7 1.4 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96302.1 - 1.3e-05 24.9 0.0 0.019 14.7 0.0 1.7 1 1 1 2 2 2 2 Leucine rich repeat 2_5_RNA_ligase2 PF13563.6 EAX96303.1 - 3e-11 43.5 0.0 4.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EAX96303.1 - 9.6e-08 32.1 0.0 4.2e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 LigT like Phosphoesterase HVSL PF09749.9 EAX96303.1 - 0.0018 17.8 2.9 0.022 14.2 1.0 2.3 2 1 0 2 2 2 1 Uncharacterised conserved protein LRR_5 PF13306.6 EAX96304.1 - 9.4e-102 336.0 70.7 8.3e-27 93.7 4.1 7.0 1 1 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96304.1 - 4.4e-22 77.6 3.9 0.026 14.3 0.0 8.8 7 3 4 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 EAX96304.1 - 5.1e-07 29.9 8.4 0.12 12.8 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAX96304.1 - 2.7 8.2 10.1 20 5.4 2.8 5.0 4 1 1 5 5 5 0 Pentapeptide repeats (9 copies) WD40 PF00400.32 EAX96305.1 - 0.0059 17.4 0.3 0.057 14.3 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Menin PF05053.13 EAX96305.1 - 0.17 10.2 4.3 0.27 9.6 4.3 1.2 1 0 0 1 1 1 0 Menin zf-RING_5 PF14634.6 EAX96306.1 - 0.00052 19.9 9.1 0.0013 18.6 9.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAX96306.1 - 0.0011 19.2 9.7 0.0043 17.3 9.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EAX96306.1 - 0.0039 16.9 6.8 0.0039 16.9 6.8 2.6 2 0 0 2 2 2 1 RING-like zinc finger HR_lesion PF05514.11 EAX96306.1 - 0.02 15.1 1.8 3.3 7.9 0.1 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing Vps39_2 PF10367.9 EAX96306.1 - 0.034 14.6 2.2 0.034 14.6 2.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 EAX96306.1 - 0.2 11.7 10.6 0.52 10.4 10.7 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 EAX96306.1 - 0.44 10.5 7.8 1.3 8.9 7.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAX96306.1 - 0.49 10.3 12.5 0.38 10.6 10.2 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAX96306.1 - 6.1 7.2 11.8 27 5.1 11.8 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Folliculin PF11704.8 EAX96307.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport EnY2 PF10163.9 EAX96307.1 - 0.0076 16.6 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2960 PF11173.8 EAX96308.1 - 0.027 14.9 0.4 0.058 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) YpjP PF14005.6 EAX96308.1 - 0.054 13.5 2.1 0.25 11.4 0.5 2.5 2 1 1 3 3 3 0 YpjP-like protein DUF4107 PF13389.6 EAX96309.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX96309.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX96310.1 - 0.067 12.9 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX96312.1 - 2.9e-28 99.0 12.8 1.4e-27 96.7 12.8 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PadR PF03551.14 EAX96313.1 - 0.041 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PapD_N PF00345.20 EAX96313.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3839 PF12943.7 EAX96315.1 - 5.3e-144 477.9 9.9 6.6e-144 477.6 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX96315.1 - 0.27 11.7 2.2 5 7.7 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX96315.1 - 0.47 10.9 3.3 4.5 7.8 0.2 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX96315.1 - 1.1 9.6 5.2 11 6.4 0.0 3.5 3 1 1 4 4 4 0 Tup N-terminal CRAL_TRIO_2 PF13716.6 EAX96316.1 - 0.00037 20.7 0.3 0.00037 20.7 0.3 3.8 4 0 0 4 4 4 1 Divergent CRAL/TRIO domain SPT_ssu-like PF11779.8 EAX96316.1 - 0.048 13.3 3.0 0.2 11.3 3.0 2.1 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like MRP-S28 PF10213.9 EAX96316.1 - 0.09 13.2 0.1 0.32 11.4 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein DUF5438 PF17506.2 EAX96316.1 - 5.7 7.3 8.2 1.5 9.2 0.4 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5438) DUF5365 PF17326.2 EAX96317.1 - 0.013 15.9 0.1 0.028 14.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX96317.1 - 0.027 14.8 0.3 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 PWI domain DUF4107 PF13389.6 EAX96319.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2939 PF11159.8 EAX96320.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX96320.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX96320.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX96321.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX96322.1 - 0.071 13.1 10.1 0.095 12.7 10.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF5327 PF17261.2 EAX96322.1 - 0.32 11.8 2.0 21 5.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) MULE PF10551.9 EAX96324.1 - 2.5e-05 24.6 0.1 4.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 EAX96324.1 - 0.059 13.5 3.6 0.11 12.6 3.6 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX96324.1 - 0.073 13.8 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain CLN3 PF02487.17 EAX96325.1 - 7.4e-42 143.8 27.4 4.4e-40 137.9 27.4 2.0 1 1 0 1 1 1 1 CLN3 protein WBP-1 PF11669.8 EAX96325.1 - 0.036 14.7 8.6 0.27 11.9 0.4 3.1 2 1 1 3 3 3 0 WW domain-binding protein 1 Sulfatase PF00884.23 EAX96326.1 - 1.5e-14 54.1 0.0 3.1e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Sulfatase DnaJ PF00226.31 EAX96327.1 - 5.6e-25 87.2 0.4 5.6e-25 87.2 0.4 2.6 2 1 1 3 3 3 1 DnaJ domain DnaJ_C PF01556.18 EAX96327.1 - 9.3e-20 71.2 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EAX96327.1 - 2e-05 24.8 10.7 3.8e-05 24.0 10.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Cep57_CLD_2 PF14197.6 EAX96327.1 - 0.08 13.0 2.9 0.073 13.2 1.5 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4337 PF14235.6 EAX96327.1 - 0.15 12.2 1.5 0.28 11.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Uteroglobin PF01099.17 EAX96327.1 - 0.17 12.3 0.6 0.44 10.9 0.6 1.6 1 0 0 1 1 1 0 Uteroglobin family Anti-TRAP PF15777.5 EAX96327.1 - 2.8 8.0 15.1 0.38 10.7 4.2 2.6 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ank_5 PF13857.6 EAX96328.1 - 0.0046 17.2 0.4 0.21 11.9 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96328.1 - 0.029 14.9 0.1 0.071 13.7 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96328.1 - 0.095 13.3 0.2 1.7 9.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Laminin_G_3 PF13385.6 EAX96329.1 - 1.4e-07 31.7 2.9 2.5e-07 31.0 2.9 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 EAX96329.1 - 0.028 13.7 2.2 0.049 12.9 0.1 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4704) mCpol PF18182.1 EAX96330.1 - 0.01 16.2 0.5 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 minimal CRISPR polymerase domain Mcl1_mid PF12341.8 EAX96330.1 - 0.072 12.4 0.2 0.22 10.9 0.1 1.8 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EAX96330.1 - 0.085 13.2 0.5 3.8 7.9 0.1 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MutS_III PF05192.18 EAX96331.1 - 0.047 13.9 0.2 0.05 13.8 0.2 1.2 1 0 0 1 1 1 0 MutS domain III DUF4106 PF13388.6 EAX96332.1 - 4.4e-279 925.5 36.5 2.4e-146 488.2 8.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX96332.1 - 0.0009 19.5 0.2 0.036 14.4 0.3 2.4 2 0 0 2 2 2 1 Kidney androgen-regulated Alph_Pro_TM PF09608.10 EAX96332.1 - 0.071 12.9 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) MnmE_helical PF12631.7 EAX96332.1 - 0.078 13.1 1.2 0.18 11.9 1.2 1.6 1 0 0 1 1 1 0 MnmE helical domain Pox_A32 PF04665.12 EAX96335.1 - 8.1e-05 22.2 2.3 8.1e-05 22.2 2.3 1.6 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX96335.1 - 0.0059 16.6 0.8 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX96335.1 - 0.044 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Zincin_2 PF10103.9 EAX96336.1 - 0.19 11.0 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAX96336.1 - 0.91 9.8 5.6 1.4 9.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly_rich PF12810.7 EAX96337.1 - 4.4e-54 184.0 33.6 5.2e-54 183.7 33.6 1.1 1 0 0 1 1 1 1 Glycine rich protein Spatacsin_C PF14649.6 EAX96338.1 - 3.3e-10 39.6 0.1 5e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Spatacsin C-terminus P_C10 PF14974.6 EAX96338.1 - 0.067 13.3 0.1 2.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein C10 SEP PF08059.13 EAX96339.1 - 5e-11 43.0 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain ZnuA PF01297.17 EAX96339.1 - 0.007 15.8 0.1 0.0094 15.4 0.1 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF327 PF03885.13 EAX96339.1 - 0.014 15.3 0.7 0.58 10.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) CHD5 PF04420.14 EAX96339.1 - 0.015 15.2 0.3 0.029 14.3 0.3 1.5 1 0 0 1 1 1 0 CHD5-like protein Spc29 PF17082.5 EAX96339.1 - 0.017 15.0 0.7 0.024 14.5 0.7 1.3 1 1 0 1 1 1 0 Spindle Pole Component 29 PDGLE PF13190.6 EAX96339.1 - 0.084 12.8 0.1 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 PDGLE domain TraF PF13728.6 EAX96339.1 - 0.085 12.7 0.2 0.085 12.7 0.2 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein YabA PF06156.13 EAX96339.1 - 0.16 12.6 2.3 0.39 11.4 2.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA DASH_Dad3 PF08656.10 EAX96339.1 - 0.2 11.8 3.9 3.1 7.9 3.9 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad3 CENP-H PF05837.12 EAX96339.1 - 0.31 11.5 5.6 0.4 11.1 4.5 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 EAX96339.1 - 0.98 10.2 5.7 0.82 10.4 0.7 2.7 3 0 0 3 3 3 0 Occludin homology domain DivIC PF04977.15 EAX96339.1 - 2.3 8.1 8.3 0.95 9.3 5.3 1.9 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 EAX96340.1 - 8.7e-45 153.1 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96340.1 - 9.5e-15 54.6 0.0 2.5e-14 53.2 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase UL16 PF17622.2 EAX96340.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Viral unique long protein 16 RPEL PF02755.15 EAX96340.1 - 0.14 11.9 0.1 14 5.5 0.0 2.7 2 0 0 2 2 2 0 RPEL repeat Lactamase_B PF00753.27 EAX96341.1 - 1.1e-10 41.9 0.0 1.3e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1967 PF09269.11 EAX96341.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF1071 PF06378.11 EAX96341.1 - 0.13 11.8 0.1 1.1 8.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) Ank_2 PF12796.7 EAX96343.1 - 2.9e-37 127.1 2.1 1.4e-14 54.4 0.9 5.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96343.1 - 1.5e-34 117.9 0.9 1.3e-09 38.4 0.0 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96343.1 - 1e-28 99.0 6.3 5.5e-09 36.1 0.0 5.1 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96343.1 - 2.6e-25 85.7 5.9 0.00053 20.2 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EAX96343.1 - 9.8e-24 82.7 3.2 4.5e-05 23.7 1.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat ATP_bind_1 PF03029.17 EAX96344.1 - 2.2e-15 57.1 0.1 2.6e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RRM_1 PF00076.22 EAX96345.1 - 0.14 12.0 0.2 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP70 PF02990.16 EAX96346.1 - 3.5e-92 309.7 26.7 5.8e-92 309.0 26.7 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 VMA21 PF09446.10 EAX96347.1 - 2.7e-06 27.4 5.8 3.4e-06 27.1 5.8 1.0 1 0 0 1 1 1 1 VMA21-like domain Cyt_c_ox_IV PF12270.8 EAX96347.1 - 0.023 14.9 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF5305 PF17231.2 EAX96347.1 - 0.065 12.6 0.4 0.12 11.8 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5305) OAD_gamma PF04277.13 EAX96347.1 - 0.32 11.6 2.2 0.38 11.4 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_L38e PF01781.18 EAX96349.1 - 1.2e-21 76.6 1.1 1.3e-21 76.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family LisH_2 PF16045.5 EAX96349.1 - 0.22 10.6 0.5 0.33 10.0 0.5 1.3 1 0 0 1 1 1 0 LisH DUF667 PF05018.13 EAX96350.1 - 7.2e-12 45.4 1.8 1.1e-11 44.8 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pox_Ag35 PF03286.14 EAX96350.1 - 0.29 10.9 5.3 0.51 10.1 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vac14_Fab1_bd PF12755.7 EAX96351.1 - 0.026 15.1 0.1 0.058 14.0 0.1 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region PhoQ_Sensor PF08918.10 EAX96351.1 - 0.21 11.4 2.1 28 4.5 0.0 2.8 2 0 0 2 2 2 0 PhoQ Sensor Baculo_FP PF03258.14 EAX96352.1 - 0.022 14.9 1.1 0.095 12.8 1.1 2.2 1 0 0 1 1 1 0 Baculovirus FP protein DnaGprimase_HBD PF16730.5 EAX96352.1 - 0.093 12.8 9.9 1.4 9.0 0.2 4.3 2 1 1 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain UNC45-central PF11701.8 EAX96354.1 - 0.016 15.2 0.7 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF3839 PF12943.7 EAX96355.1 - 1.2e-152 506.2 12.3 1.5e-152 505.9 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX96355.1 - 0.21 11.4 1.4 0.74 9.7 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX96355.1 - 1.4 9.2 4.4 2 8.7 0.1 3.0 2 2 1 3 3 3 0 Rx N-terminal domain DUF1493 PF07377.12 EAX96356.1 - 0.069 13.6 0.5 0.15 12.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX96357.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96358.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4957 PF16318.5 EAX96360.1 - 0.09 12.7 2.8 0.25 11.3 0.0 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4957) Ank_2 PF12796.7 EAX96361.1 - 3.4e-53 178.2 1.2 6.5e-15 55.5 0.3 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96361.1 - 3.9e-40 134.6 0.0 1.3e-05 25.4 0.1 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAX96361.1 - 1.7e-39 133.7 0.1 1e-07 32.3 0.0 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96361.1 - 8.8e-38 127.9 0.1 2.2e-06 27.8 0.0 7.4 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96361.1 - 2.1e-34 113.6 1.1 0.0025 18.2 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Inos-1-P_synth PF01658.17 EAX96361.1 - 0.096 12.9 0.2 0.52 10.6 0.2 2.3 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Ank_2 PF12796.7 EAX96362.1 - 1.5e-57 192.1 3.1 4.7e-18 65.6 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96362.1 - 3.5e-38 129.5 0.0 2.3e-09 37.6 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96362.1 - 8.8e-29 99.2 0.0 0.00024 21.3 0.0 6.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96362.1 - 9.2e-28 93.2 0.0 0.0092 16.4 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 EAX96362.1 - 3.4e-26 90.5 0.0 0.0012 19.2 0.0 7.4 5 2 2 7 7 7 5 Ankyrin repeat YfmQ PF10787.9 EAX96362.1 - 0.0032 17.3 0.1 6.8 6.5 0.0 4.0 2 2 2 4 4 4 1 Uncharacterised protein from bacillus cereus group DUF2443 PF10398.9 EAX96362.1 - 0.016 15.2 2.9 0.025 14.6 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) Vps4_C PF09336.10 EAX96362.1 - 0.03 14.3 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF2115 PF09888.9 EAX96362.1 - 0.035 14.6 1.8 0.44 11.0 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4298 PF14131.6 EAX96362.1 - 0.047 13.6 0.8 0.12 12.4 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Response_reg PF00072.24 EAX96362.1 - 0.087 13.0 0.3 7.1 6.8 0.0 3.6 2 1 2 4 4 4 0 Response regulator receiver domain Ribosomal_L27e PF01777.18 EAX96363.1 - 2.2e-21 76.0 6.8 2.8e-21 75.6 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAX96363.1 - 0.0062 16.4 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAX96363.1 - 0.16 11.4 0.1 0.18 11.2 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Sec23_trunk PF04811.15 EAX96364.1 - 2.8e-20 72.9 0.0 4.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EAX96364.1 - 0.00016 21.6 5.8 0.0004 20.4 5.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EAX96364.1 - 0.00044 20.9 0.1 0.001 19.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 EAX96364.1 - 0.6 9.5 5.7 14 5.2 0.1 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2HC5 PF06221.13 EAX96364.1 - 1.5 8.8 6.2 3.7 7.6 6.2 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PhnA_Zn_Ribbon PF08274.12 EAX96364.1 - 3.1 7.8 6.4 7.1 6.7 6.4 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Ipi1_N PF12333.8 EAX96365.1 - 0.0024 18.4 0.6 0.66 10.6 0.0 2.9 2 0 0 2 2 2 2 Rix1 complex component involved in 60S ribosome maturation BUD22 PF09073.10 EAX96366.1 - 6.7e-05 22.4 26.3 9.3e-05 21.9 26.3 1.2 1 0 0 1 1 1 1 BUD22 Endostatin PF06482.11 EAX96366.1 - 8.4 5.8 7.7 18 4.7 7.7 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Gly_rich PF12810.7 EAX96368.1 - 7.2e-48 163.6 35.6 9.1e-48 163.3 35.6 1.1 1 0 0 1 1 1 1 Glycine rich protein Pkinase PF00069.25 EAX96369.1 - 8.6e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96369.1 - 1.7e-33 116.0 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96369.1 - 0.00011 21.6 0.0 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX96369.1 - 0.00061 19.2 0.2 0.0011 18.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX96369.1 - 0.00063 18.8 0.9 0.0011 18.1 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX96369.1 - 0.56 10.1 4.0 0.17 11.7 0.3 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4101 PF13355.6 EAX96370.1 - 0.14 12.6 0.4 0.41 11.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4101) DUF3839 PF12943.7 EAX96372.1 - 2.7e-156 518.2 11.1 3.4e-156 517.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96372.1 - 0.019 15.4 2.2 0.04 14.4 0.6 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96372.1 - 0.061 13.8 3.5 2.2 8.8 0.1 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX96372.1 - 0.073 13.4 0.7 5.2 7.4 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain TMP PF05017.14 EAX96374.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96375.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ACP_PD PF04336.12 EAX96379.1 - 0.022 15.2 0.2 0.91 10.0 0.0 3.4 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase DUF4107 PF13389.6 EAX96381.1 - 1.4e-71 239.9 3.9 1.8e-71 239.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX96381.1 - 0.17 10.3 0.7 0.22 9.9 0.7 1.2 1 0 0 1 1 1 0 Lipoxygenase Dzip-like_N PF13815.6 EAX96385.1 - 9.8e-13 48.1 0.6 9.8e-13 48.1 0.6 3.1 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_2 PF12756.7 EAX96385.1 - 0.0086 16.4 0.1 0.029 14.7 0.1 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAX96385.1 - 0.044 14.6 0.4 0.11 13.5 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAX96385.1 - 0.14 12.4 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF885 PF05960.11 EAX96385.1 - 0.43 10.2 6.8 1.1 8.8 6.8 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) LMBR1 PF04791.16 EAX96385.1 - 6 5.7 7.5 13 4.6 7.5 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein PPO1_KFDV PF12143.8 EAX96386.1 - 4.9 7.3 8.2 5.2 7.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF_B2219) DUF1465 PF07323.12 EAX96387.1 - 0.0026 17.6 8.2 0.0036 17.2 7.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1465) DUF1640 PF07798.11 EAX96387.1 - 0.088 12.9 12.4 0.14 12.2 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc29 PF17082.5 EAX96387.1 - 0.091 12.6 11.3 0.21 11.4 11.3 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Spc7 PF08317.11 EAX96387.1 - 0.12 11.2 17.8 0.18 10.7 17.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 EAX96387.1 - 0.14 11.6 4.8 0.19 11.2 4.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Exonuc_VII_L PF02601.15 EAX96387.1 - 0.26 10.8 6.3 0.28 10.7 6.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EAX96387.1 - 0.71 7.7 8.9 0.77 7.6 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 EAX96387.1 - 1.1 8.0 8.6 1.3 7.8 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc24 PF08286.11 EAX96387.1 - 1.4 9.2 19.9 1.1 9.5 5.3 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Iron_permease PF04120.12 EAX96387.1 - 2.4 7.9 6.6 4.6 7.0 6.6 1.4 1 0 0 1 1 1 0 Low affinity iron permease DUF1664 PF07889.12 EAX96387.1 - 3.1 7.9 15.7 3.1 7.9 3.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EAX96387.1 - 3.6 6.4 10.7 4.1 6.2 10.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 EAX96387.1 - 8.2 5.1 9.7 10 4.8 9.7 1.1 1 0 0 1 1 1 0 Presenilin Ank_5 PF13857.6 EAX96389.1 - 1.1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96389.1 - 1.7e-08 34.9 0.0 1.7e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96389.1 - 2.4e-06 28.0 0.0 3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX96389.1 - 5.4e-05 23.5 0.7 0.061 13.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX96389.1 - 0.00029 21.0 0.1 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Golgin_A5 PF09787.9 EAX96390.1 - 0.00052 19.6 2.8 0.00065 19.3 2.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Adenine_glyco PF03352.13 EAX96390.1 - 0.0054 16.5 2.8 0.006 16.4 2.8 1.1 1 0 0 1 1 1 1 Methyladenine glycosylase Med22 PF06179.12 EAX96390.1 - 0.011 15.9 4.2 0.017 15.3 4.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex HTH_40 PF14493.6 EAX96390.1 - 0.031 14.7 1.8 0.031 14.7 1.8 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain bPH_4 PF06713.11 EAX96390.1 - 0.072 13.2 3.9 0.22 11.6 3.9 1.8 1 1 0 1 1 1 0 Bacterial PH domain ImcF-related_N PF14331.6 EAX96390.1 - 0.098 12.0 0.1 0.11 11.8 0.1 1.0 1 0 0 1 1 1 0 ImcF-related N-terminal domain TcdB_N PF12918.7 EAX96390.1 - 0.62 10.4 10.4 11 6.4 2.1 3.3 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain ASL_C PF08328.11 EAX96390.1 - 0.66 10.1 4.2 0.54 10.4 0.4 2.3 2 1 1 3 3 3 0 Adenylosuccinate lyase C-terminal DUF5527 PF17665.1 EAX96391.1 - 0.13 11.8 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) VHS PF00790.19 EAX96391.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 VHS domain KilA-N PF04383.13 EAX96392.1 - 7e-35 119.3 0.2 1e-34 118.8 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX96393.1 - 2.5e-06 27.9 0.7 6e-06 26.7 0.3 1.8 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX96393.1 - 0.04 13.4 0.3 0.54 9.8 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX96394.1 - 1.8e-156 518.8 14.6 2.2e-156 518.5 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX96394.1 - 0.039 14.2 1.2 0.076 13.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX96394.1 - 0.055 13.9 2.1 0.14 12.6 0.4 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96394.1 - 2.3 8.8 9.7 4.1 7.9 2.1 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX96395.1 - 0.088 13.4 5.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96396.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF962 PF06127.11 EAX96399.1 - 1.9e-15 56.7 9.7 1e-14 54.4 9.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SH3_3 PF08239.11 EAX96401.1 - 1.9e-26 92.1 11.2 7.1e-14 51.8 2.7 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 EAX96401.1 - 3.8e-20 71.5 0.1 5.7e-10 38.9 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain DUF261 PF03196.13 EAX96401.1 - 9.5e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF261 SH3_2 PF07653.17 EAX96401.1 - 0.035 13.8 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain SH3_9 PF14604.6 EAX96401.1 - 0.27 11.1 1.2 0.55 10.1 0.1 2.1 2 0 0 2 2 2 0 Variant SH3 domain DUF3839 PF12943.7 EAX96402.1 - 9e-136 451.0 10.7 1.1e-135 450.7 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96402.1 - 0.092 13.2 3.0 0.12 12.8 0.6 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX96402.1 - 0.13 12.7 0.4 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX96402.1 - 0.81 10.2 7.0 5.2 7.6 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX96404.1 - 7.1e-21 74.0 8.2 2.5e-16 59.5 3.1 4.6 6 0 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX96404.1 - 0.067 12.9 0.2 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAX96404.1 - 0.075 13.0 3.6 2.9 7.8 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) TMP PF05017.14 EAX96406.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96407.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Lactamase_B_2 PF12706.7 EAX96408.1 - 1.2e-10 41.2 0.0 1.4e-09 37.8 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAX96408.1 - 0.00082 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily F5_F8_type_C PF00754.25 EAX96409.1 - 4.8e-06 26.7 0.2 4.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain PUA_2 PF14306.6 EAX96409.1 - 0.052 13.2 0.3 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 PUA-like domain F5_F8_type_C PF00754.25 EAX96410.1 - 1.4e-06 28.4 0.1 5.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX96411.1 - 1.9e-05 24.7 0.0 0.00043 20.4 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX96412.1 - 1.7e-06 28.1 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Fn3_assoc PF13287.6 EAX96413.1 - 6.8 6.9 12.1 3.1 8.0 4.4 4.9 2 1 0 2 2 2 0 Fn3 associated F5_F8_type_C PF00754.25 EAX96414.1 - 2.3e-06 27.8 0.0 9.3e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAX96415.1 - 1.4e-09 38.2 0.1 3.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain F5_F8_type_C PF00754.25 EAX96416.1 - 1.4e-06 28.5 0.0 3.8e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain LRR_5 PF13306.6 EAX96417.1 - 1.4e-43 147.9 53.5 2.1e-21 76.2 6.6 5.2 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96417.1 - 1.1e-08 34.7 0.8 0.03 14.1 0.1 5.2 5 2 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EAX96417.1 - 0.035 14.5 4.4 16 6.1 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) ARA70 PF12489.8 EAX96418.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator DUF3139 PF11337.8 EAX96419.1 - 0.046 14.4 9.0 0.4 11.4 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) sCache_3_2 PF17203.4 EAX96421.1 - 0.00048 20.3 0.1 0.00048 20.3 0.1 2.4 3 0 0 3 3 3 1 Single cache domain 3 Na_trans_assoc PF06512.13 EAX96421.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.2 2 1 1 3 3 3 0 Sodium ion transport-associated Ank_2 PF12796.7 EAX96422.1 - 1.8e-70 233.6 53.7 1.4e-15 57.6 2.3 5.9 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96422.1 - 2e-57 190.8 26.2 1.4e-13 51.0 0.2 10.1 3 1 7 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX96422.1 - 2.8e-52 173.0 21.2 9.5e-09 35.3 0.6 8.9 8 0 0 8 8 8 7 Ankyrin repeat DUF3447 PF11929.8 EAX96422.1 - 1.4e-39 133.9 7.0 1.4e-39 133.9 7.0 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX96422.1 - 4.2e-38 125.0 13.3 4.9e-06 26.5 0.1 9.2 10 0 0 10 10 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX96422.1 - 7.3e-30 102.6 10.4 2.3e-09 37.3 0.1 6.0 4 1 3 7 7 7 6 Ankyrin repeats (many copies) DUF4100 PF13352.6 EAX96422.1 - 0.00018 21.4 2.9 0.59 9.9 0.1 3.7 2 1 1 3 3 3 2 Protein of unknown function (DUF4100) DUF3718 PF12514.8 EAX96422.1 - 0.015 15.4 10.2 52 4.1 0.1 6.1 2 1 4 6 6 6 0 Protein of unknown function (DUF3718) Ribosomal_S6 PF01250.17 EAX96422.1 - 0.066 13.5 0.4 16 5.9 0.0 3.9 1 1 3 4 4 4 0 Ribosomal protein S6 PH_8 PF15409.6 EAX96422.1 - 0.11 12.8 0.5 88 3.5 0.0 4.9 2 1 4 7 7 7 0 Pleckstrin homology domain ACP53EA PF06313.11 EAX96422.1 - 0.24 11.6 1.6 0.75 10.0 0.3 2.4 2 0 0 2 2 2 0 Drosophila ACP53EA protein DUF3188 PF11384.8 EAX96423.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Ank_2 PF12796.7 EAX96424.1 - 2.2e-14 53.8 8.4 5.3e-06 26.9 0.1 5.2 2 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96424.1 - 1e-09 38.7 5.8 0.12 13.0 0.0 6.0 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96424.1 - 4.5e-06 26.6 11.2 0.32 11.7 0.0 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 EAX96424.1 - 2.6e-05 24.4 0.1 0.43 11.0 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX96424.1 - 0.00038 20.8 8.4 0.22 12.0 0.1 5.6 7 0 0 7 7 7 2 Ankyrin repeat DUF4116 PF13475.6 EAX96424.1 - 1.8 8.3 6.4 1.3 8.8 1.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4116) Ank_2 PF12796.7 EAX96425.1 - 2.5e-43 146.6 32.9 2.4e-07 31.2 0.1 13.0 6 4 7 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96425.1 - 8.7e-28 96.3 16.6 0.0049 17.4 0.0 14.7 12 4 3 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96425.1 - 1.9e-27 92.3 28.5 0.001 19.4 0.0 18.8 21 0 0 21 21 21 6 Ankyrin repeat Ank_5 PF13857.6 EAX96425.1 - 1.1e-19 70.2 2.5 0.0012 19.2 0.0 9.2 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX96425.1 - 3.4e-14 52.5 14.7 0.0096 16.3 0.0 12.2 13 1 1 14 14 14 2 Ankyrin repeat DUF3447 PF11929.8 EAX96425.1 - 1e-08 35.0 0.9 1e-08 35.0 0.9 15.0 9 5 6 15 15 15 6 Domain of unknown function (DUF3447) DpnI_C PF17726.1 EAX96425.1 - 0.0092 16.1 0.7 0.15 12.2 0.8 3.1 2 0 0 2 2 2 1 Dam-replacing HTH domain DUF3839 PF12943.7 EAX96426.1 - 2.8e-154 511.6 15.6 3.4e-154 511.3 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAX96426.1 - 0.014 15.7 0.4 0.25 11.6 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAX96426.1 - 0.025 15.1 3.4 0.61 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX96426.1 - 0.098 12.5 1.6 0.25 11.2 0.3 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX96426.1 - 0.38 11.2 8.4 1.6 9.2 1.5 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX96427.1 - 8.6e-07 29.5 0.1 2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX96427.1 - 0.0043 16.9 0.1 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX96427.1 - 0.024 14.2 0.6 0.074 12.6 0.3 1.8 2 0 0 2 2 2 0 Legume lectin domain LRR_5 PF13306.6 EAX96428.1 - 8.5e-34 116.3 19.1 2.8e-16 59.6 4.0 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96428.1 - 8.3e-15 54.3 4.3 4.7e-08 32.7 0.1 4.5 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX96428.1 - 7.3e-06 26.2 2.7 0.0027 18.1 0.3 5.1 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) DUF3839 PF12943.7 EAX96429.1 - 3.8e-154 511.1 11.5 4.6e-154 510.9 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX96429.1 - 0.069 13.6 3.1 4.6 7.8 0.1 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Flavi_NS4A PF01350.17 EAX96430.1 - 0.055 13.4 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A DUF2207 PF09972.9 EAX96430.1 - 0.28 9.9 1.0 0.3 9.8 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3447 PF11929.8 EAX96431.1 - 2.8e-08 33.6 12.2 2.7e-07 30.5 5.5 3.7 2 2 2 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96431.1 - 0.004 17.7 0.3 0.11 13.1 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96431.1 - 0.012 16.1 1.5 68 4.5 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat SHIPPO-rpt PF07004.12 EAX96434.1 - 0.009 16.9 12.6 3.2 8.8 0.0 4.2 4 1 0 4 4 4 3 Sperm-tail PG-rich repeat HSP70 PF00012.20 EAX96436.1 - 5.1e-12 44.8 2.0 5.1e-12 44.8 2.0 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EAX96436.1 - 2.7e-05 23.1 0.3 6.4e-05 21.9 0.3 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Herpes_BLRF2 PF05812.12 EAX96436.1 - 1 9.5 4.0 8.7 6.5 0.3 2.9 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein BET PF17035.5 EAX96437.1 - 1.1e-07 31.9 3.5 1.1e-07 31.9 3.5 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EAX96437.1 - 0.00033 20.6 1.3 0.0017 18.4 1.3 2.1 1 1 0 1 1 1 1 Bromodomain Alpha_L_fucos PF01120.17 EAX96437.1 - 0.012 15.1 0.5 0.065 12.7 0.2 1.9 2 0 0 2 2 2 0 Alpha-L-fucosidase DUF1951 PF09188.10 EAX96437.1 - 0.014 15.4 1.0 0.029 14.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) PhdYeFM_antitox PF02604.19 EAX96437.1 - 0.11 12.4 0.5 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Ank_4 PF13637.6 EAX96438.1 - 8.3e-10 39.0 0.1 1e-05 25.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX96438.1 - 6e-09 36.0 0.2 2.4e-06 27.7 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX96438.1 - 8.4e-09 35.5 0.0 9.4e-07 29.0 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96438.1 - 2e-08 33.8 0.1 3e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX96438.1 - 3.4e-08 34.0 0.1 6e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX96438.1 - 0.00022 21.1 4.6 0.011 15.6 0.5 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Pkinase PF00069.25 EAX96439.1 - 1.2e-24 87.2 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96439.1 - 3.7e-16 59.2 0.0 4.7e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX96439.1 - 9.3e-07 29.0 0.1 0.00016 21.7 0.0 3.1 2 2 2 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX96439.1 - 3.3e-05 23.3 0.0 6.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX96439.1 - 0.00025 20.0 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EAX96439.1 - 0.0045 16.0 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 EAX96439.1 - 0.13 11.9 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.7 EAX96440.1 - 5.1e-11 43.0 0.0 1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96440.1 - 1.3e-09 38.2 0.1 3.3e-06 27.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96440.1 - 3.6e-07 30.0 0.0 0.074 13.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX96440.1 - 1.1e-06 29.0 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX96440.1 - 3.7e-06 27.1 0.0 0.0052 17.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat HALZ PF02183.18 EAX96440.1 - 0.078 13.2 29.1 5.5 7.3 0.8 6.2 2 1 4 6 6 6 0 Homeobox associated leucine zipper Methyltransf_31 PF13847.6 EAX96440.1 - 0.085 12.6 5.1 0.25 11.1 5.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sec2p PF06428.11 EAX96440.1 - 0.53 10.3 28.0 9.5 6.3 4.9 4.5 1 1 4 5 5 5 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 EAX96440.1 - 0.61 10.8 23.7 4.1 8.1 10.2 3.3 1 1 1 2 2 2 0 Initiation control protein YabA BRE1 PF08647.11 EAX96440.1 - 0.69 10.0 26.1 5.2 7.2 13.3 3.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.19 EAX96440.1 - 2.3 6.0 16.4 3.1 5.6 16.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 EAX96440.1 - 5.1 7.2 19.2 35 4.5 1.5 3.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ALMT PF11744.8 EAX96440.1 - 6.4 5.5 14.9 8.1 5.2 14.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAR1 PF03101.15 EAX96441.1 - 0.057 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Baculo_E66 PF04850.12 EAX96441.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein Transposase_mut PF00872.18 EAX96442.1 - 0.0031 16.4 0.8 0.0042 16.0 0.4 1.5 1 1 0 1 1 1 1 Transposase, Mutator family Amidase02_C PF12123.8 EAX96443.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX96443.1 - 0.19 11.6 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX96444.1 - 2.2e-72 242.5 3.1 3.1e-72 242.0 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX96446.1 - 6.5e-07 29.7 2.0 2.7e-06 27.7 1.1 2.3 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX96446.1 - 0.0037 16.2 0.3 0.0061 15.5 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Ran_BP1 PF00638.18 EAX96447.1 - 7.9e-06 26.1 0.0 1.2e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 RanBP1 domain Folate_rec PF03024.14 EAX96448.1 - 0.44 10.4 2.3 0.51 10.2 0.7 1.9 2 0 0 2 2 2 0 Folate receptor family Ran_BP1 PF00638.18 EAX96449.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Sir1 PF11603.8 EAX96450.1 - 0.11 13.0 1.1 3 8.4 0.1 2.3 2 0 0 2 2 2 0 Regulatory protein Sir1 Abhydrolase_1 PF00561.20 EAX96451.1 - 1.3e-12 48.0 0.0 6.4e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAX96451.1 - 4.8e-12 46.9 0.0 5.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAX96451.1 - 1.2e-10 41.1 0.0 2.9e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EAX96451.1 - 3.1e-05 23.9 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase FSH1 PF03959.13 EAX96451.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 EAX96451.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GPS2_interact PF15784.5 EAX96453.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX96453.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX96454.1 - 0.11 12.4 12.3 0.12 12.3 12.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX96454.1 - 0.7 10.3 6.1 0.81 10.1 6.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_2 PF12796.7 EAX96455.1 - 8.1e-06 26.3 0.1 0.0028 18.2 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96455.1 - 4.9e-05 23.4 0.2 0.41 11.4 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX96455.1 - 0.00013 21.8 0.5 0.00013 21.8 0.5 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX96455.1 - 0.00047 20.7 0.5 0.12 13.0 0.0 4.1 5 1 1 6 6 6 1 Ankyrin repeats (many copies) DUF1823 PF08853.11 EAX96455.1 - 0.059 13.6 0.0 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) Prismane PF03063.20 EAX96456.1 - 0.013 14.2 0.1 0.013 14.2 0.1 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family IRF-3 PF10401.9 EAX96457.1 - 0.091 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-regulatory factor 3 B56 PF01603.20 EAX96458.1 - 1.2e-138 462.6 12.8 1.4e-138 462.4 12.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) tRNA-synt_1 PF00133.22 EAX96459.1 - 2.1e-200 667.0 0.2 2.9e-200 666.6 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAX96459.1 - 4e-27 95.1 0.5 1.5e-26 93.2 0.2 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAX96459.1 - 2.2e-17 62.9 1.2 0.00011 21.1 0.1 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EAX96459.1 - 0.083 12.4 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 LRR_5 PF13306.6 EAX96460.1 - 1.7e-99 328.7 71.9 4.1e-25 88.2 14.7 7.0 3 1 4 8 8 8 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96460.1 - 7.7e-13 48.0 10.0 0.0012 18.5 0.9 9.0 6 2 5 11 11 11 4 Leucine rich repeat LRR_4 PF12799.7 EAX96460.1 - 0.12 12.9 23.8 22 5.6 1.9 8.4 9 1 1 10 10 10 0 Leucine Rich repeats (2 copies) LysM PF01476.20 EAX96461.1 - 0.00012 22.1 0.0 0.0023 18.0 0.0 2.7 3 0 0 3 3 3 1 LysM domain LysM PF01476.20 EAX96462.1 - 0.0082 16.2 2.1 0.01 15.9 0.1 2.2 3 0 0 3 3 3 1 LysM domain C2 PF00168.30 EAX96463.1 - 4.5e-18 65.4 0.0 6.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 EAX96464.1 - 5.1e-20 71.9 0.0 9.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96464.1 - 6.5e-18 64.9 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4790 PF16037.5 EAX96465.1 - 0.43 11.1 12.7 0.15 12.5 1.2 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4790) Ammonium_transp PF00909.21 EAX96467.1 - 1.4e-27 96.4 32.3 2.6e-27 95.5 32.3 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family Ras PF00071.22 EAX96468.1 - 2.1e-48 164.0 0.1 2.7e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96468.1 - 7.1e-32 110.1 0.3 1.9e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96468.1 - 2.5e-15 56.4 0.0 3.2e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX96468.1 - 2.1e-06 27.3 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX96468.1 - 3e-05 24.1 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX96468.1 - 0.00016 21.6 2.9 0.033 14.1 0.2 2.5 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAX96468.1 - 0.0016 18.8 0.0 0.0028 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAX96468.1 - 0.0056 16.4 0.4 0.016 15.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAX96468.1 - 0.014 14.9 0.3 0.053 13.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 EAX96468.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EAX96468.1 - 0.093 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAX96468.1 - 0.098 13.2 0.5 0.11 13.0 0.5 1.6 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EAX96468.1 - 0.21 12.1 0.9 1 9.9 0.9 2.0 1 1 0 1 1 1 0 AAA domain Sec7 PF01369.20 EAX96469.1 - 5.3e-45 153.3 0.0 8.4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EAX96469.1 - 1.6e-11 44.6 0.2 1.6e-11 44.6 0.2 1.9 2 0 0 2 2 2 1 PH domain DUF3719 PF12516.8 EAX96469.1 - 0.036 13.8 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Pkinase PF00069.25 EAX96470.1 - 2.8e-73 246.5 0.2 7.4e-73 245.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96470.1 - 1.7e-51 175.0 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96470.1 - 9e-10 38.3 0.0 4.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX96470.1 - 8.2e-06 25.9 0.0 0.0015 18.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX96470.1 - 0.0063 15.5 0.1 0.0063 15.5 0.1 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX96470.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF3447 PF11929.8 EAX96471.1 - 6.1e-21 74.2 26.1 3.9e-20 71.6 5.9 3.8 2 2 2 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96471.1 - 7.6e-14 52.1 1.4 4.6e-11 43.1 0.2 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96471.1 - 3.3e-13 49.8 3.4 2.2e-06 28.1 0.2 3.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96471.1 - 1.7e-12 46.3 1.6 0.00043 20.5 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX96471.1 - 2.1e-09 37.5 0.2 0.0016 18.7 0.1 4.9 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX96471.1 - 2.4e-08 34.1 0.4 1e-05 25.7 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat TPR_2 PF07719.17 EAX96472.1 - 4.1e-19 67.1 6.9 0.0046 17.0 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAX96472.1 - 1.5e-17 62.6 12.2 0.00015 21.4 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX96472.1 - 2.3e-14 53.6 0.1 0.00084 19.8 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAX96472.1 - 2.9e-13 48.9 7.1 0.13 12.6 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAX96472.1 - 1.6e-11 43.7 5.4 0.0001 21.9 0.0 5.5 4 1 1 5 5 5 3 TPR repeat TPR_6 PF13174.6 EAX96472.1 - 3.2e-11 43.1 6.5 0.04 14.6 0.2 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAX96472.1 - 1.7e-09 37.7 0.0 0.1 13.4 0.0 6.6 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX96472.1 - 5.5e-07 29.2 1.9 14 6.0 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX96472.1 - 2.1e-06 27.9 5.6 1.5 9.1 0.0 5.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX96472.1 - 2.7e-06 27.4 14.3 0.0013 19.0 0.2 6.5 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX96472.1 - 3.3e-06 26.5 0.0 1.5 8.0 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX96472.1 - 6.2e-06 26.8 0.0 0.24 12.1 0.0 4.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAX96472.1 - 1.8e-05 24.8 0.0 0.0078 16.3 0.0 3.7 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX96472.1 - 4.7e-05 23.5 3.0 0.13 12.6 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EAX96472.1 - 0.0095 15.0 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 EAX96472.1 - 0.013 15.2 0.6 2.1 8.0 0.0 3.3 2 1 2 4 4 4 0 26S proteasome subunit RPN7 MIT PF04212.18 EAX96472.1 - 0.19 11.8 1.0 1.2 9.3 0.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Gryzun-like PF12742.7 EAX96473.1 - 1.8e-22 79.1 0.1 5.2e-22 77.6 0.1 1.9 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 EAX96473.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 CLP1_N PF16573.5 EAX96473.1 - 0.022 15.0 0.1 0.19 12.0 0.1 2.4 2 0 0 2 2 2 0 N-terminal beta-sandwich domain of polyadenylation factor CTV_P23 PF04808.12 EAX96473.1 - 0.066 12.8 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Citrus tristeza virus (CTV) P23 protein CN_hydrolase PF00795.22 EAX96474.1 - 2e-57 194.5 0.0 2.2e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Metallophos PF00149.28 EAX96475.1 - 4.9e-17 63.1 0.0 2e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TMP PF05017.14 EAX96476.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96477.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Cation_ATPase_C PF00689.21 EAX96478.1 - 1.5e-37 129.1 5.4 1.5e-37 129.1 5.4 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EAX96478.1 - 9.5e-33 113.2 0.1 9.5e-33 113.2 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EAX96478.1 - 1.8e-16 61.1 0.0 4.3e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAX96478.1 - 2.4e-13 49.6 0.0 7.1e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAX96478.1 - 3.8e-13 49.3 0.0 8.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAX96478.1 - 0.00089 19.1 0.2 0.043 13.6 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3447 PF11929.8 EAX96479.1 - 3.3e-36 123.1 5.3 3.3e-36 123.1 5.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96479.1 - 1e-10 42.0 0.8 8.1e-06 26.3 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96479.1 - 3.8e-06 27.3 4.3 0.18 12.4 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96479.1 - 0.00011 22.3 4.3 0.058 14.0 0.1 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EAX96479.1 - 0.001 19.4 0.4 1.2 9.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX96479.1 - 0.0012 19.1 0.2 4.4 7.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) BRX_N PF13713.6 EAX96480.1 - 0.0089 15.8 1.0 0.0089 15.8 1.0 6.7 6 0 0 6 6 6 1 Transcription factor BRX N-terminal domain DUF3138 PF11336.8 EAX96480.1 - 0.028 13.0 0.1 0.028 13.0 0.1 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF3138) Occludin_ELL PF07303.13 EAX96480.1 - 0.045 14.5 0.5 0.045 14.5 0.5 8.7 4 3 5 9 9 9 0 Occludin homology domain SF-assemblin PF06705.11 EAX96480.1 - 0.12 11.7 121.9 0.19 11.1 29.4 5.1 1 1 3 4 4 4 0 SF-assemblin/beta giardin Lebercilin PF15619.6 EAX96480.1 - 0.52 9.9 123.3 0.02 14.5 15.6 7.0 1 1 6 7 7 7 0 Ciliary protein causing Leber congenital amaurosis disease DUF167 PF02594.16 EAX96480.1 - 4.2 7.5 8.5 1.1 9.4 0.3 3.8 4 0 0 4 4 4 0 Uncharacterised ACR, YggU family COG1872 Titin_Ig-rpts PF06582.12 EAX96480.1 - 4.3 7.4 5.8 51 3.9 0.2 3.6 3 0 0 3 3 3 0 Titin repeat Baculo_PEP_C PF04513.12 EAX96481.1 - 0.0073 16.3 4.8 0.0073 16.3 4.8 5.5 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4535 PF15054.6 EAX96481.1 - 0.014 15.1 0.1 0.014 15.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) FlaC_arch PF05377.11 EAX96481.1 - 0.018 15.4 1.1 0.018 15.4 1.1 9.0 6 3 3 9 9 9 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 EAX96481.1 - 0.078 13.4 0.4 0.078 13.4 0.4 7.3 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein YtxH PF12732.7 EAX96481.1 - 0.12 13.0 13.1 6.3e+02 1.0 0.8 5.6 1 1 1 2 2 2 0 YtxH-like protein Spc7 PF08317.11 EAX96481.1 - 0.14 11.0 62.3 1.3 7.9 10.2 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3037 PF11236.8 EAX96481.1 - 2.5 8.5 10.5 5.1 7.6 1.0 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF3037) YqzM PF14141.6 EAX96481.1 - 5.3 7.2 5.8 37 4.5 6.5 2.2 2 0 0 2 2 2 0 YqzM-like protein Tropomyosin PF00261.20 EAX96481.1 - 6.1 6.1 59.5 0.77 9.1 10.7 5.6 3 1 1 4 4 4 0 Tropomyosin Ank_5 PF13857.6 EAX96482.1 - 2.7e-25 88.1 12.2 6.1e-11 42.4 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX96482.1 - 4e-23 81.5 2.9 4e-10 40.0 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96482.1 - 3.6e-18 65.9 7.7 8.8e-18 64.7 7.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96482.1 - 2.4e-17 62.5 10.9 9.7e-07 29.0 0.3 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX96482.1 - 6.3e-15 53.8 7.6 0.00055 20.2 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat PEGA PF08308.11 EAX96482.1 - 0.075 12.9 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 PEGA domain Molydop_binding PF01568.21 EAX96482.1 - 0.081 12.9 0.2 3.5 7.7 0.1 2.2 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain DUF3447 PF11929.8 EAX96482.1 - 0.088 12.8 1.1 0.35 10.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) ArlS_N PF18719.1 EAX96482.1 - 0.091 13.0 0.2 0.26 11.5 0.1 1.7 1 1 1 2 2 2 0 ArlS sensor domain DUF3447 PF11929.8 EAX96483.1 - 1e-29 102.3 3.3 1e-29 102.3 3.3 4.7 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX96483.1 - 4e-28 96.6 5.3 3e-07 30.6 0.2 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX96483.1 - 1.8e-27 95.8 8.7 9.1e-17 61.4 4.3 3.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96483.1 - 2.5e-25 88.5 7.9 3.3e-08 33.9 0.1 5.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96483.1 - 3.9e-23 79.0 5.6 1.4e-05 25.1 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX96483.1 - 5.2e-22 77.6 1.0 1e-08 35.3 0.2 5.0 3 1 3 6 6 6 4 Ankyrin repeats (many copies) RL PF17797.1 EAX96483.1 - 0.023 14.7 14.9 1.1 9.3 0.2 4.9 4 1 0 4 4 4 0 RL domain APG6_N PF17675.1 EAX96484.1 - 0.0013 19.3 3.7 0.0013 19.3 3.7 8.1 4 2 2 7 7 7 3 Apg6 coiled-coil region DUF641 PF04859.12 EAX96484.1 - 0.0067 16.8 6.5 0.0067 16.8 6.5 7.6 5 1 2 7 7 7 2 Plant protein of unknown function (DUF641) CVNH PF08881.10 EAX96484.1 - 0.12 13.1 10.2 6.4 7.5 1.4 4.6 4 1 0 4 4 4 0 CVNH domain PKHD_C PF18331.1 EAX96484.1 - 0.16 12.1 0.2 0.94 9.6 0.2 2.4 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Ank_2 PF12796.7 EAX96485.1 - 1.4e-18 67.3 6.1 1.4e-07 32.0 0.1 2.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96485.1 - 1.9e-12 47.2 0.1 5.6e-05 23.4 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96485.1 - 5.5e-09 35.9 0.3 5.5e-09 35.9 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX96485.1 - 3.6e-08 33.0 0.3 0.18 12.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX96485.1 - 5.3e-08 33.3 2.3 0.013 16.1 0.0 4.8 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX96485.1 - 1.4e-06 28.5 0.7 0.0029 18.0 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Myb_DNA-binding PF00249.31 EAX96486.1 - 1.2e-12 47.8 0.0 8e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96486.1 - 1e-09 38.5 3.5 4e-08 33.4 1.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain CDC24 PF06395.11 EAX96486.1 - 0.0012 19.0 0.5 0.0033 17.6 0.1 1.8 2 0 0 2 2 2 1 CDC24 Calponin Myb_DNA-bind_7 PF15963.5 EAX96486.1 - 0.0035 17.2 0.7 0.11 12.4 0.0 2.5 2 1 0 2 2 2 1 Myb DNA-binding like Dehalogenase PF13486.6 EAX96486.1 - 0.024 14.0 0.3 1.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Reductive dehalogenase subunit DUF1722 PF08349.11 EAX96486.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Ank_2 PF12796.7 EAX96487.1 - 1.8e-05 25.2 0.0 2.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96487.1 - 0.00014 22.3 0.0 0.00018 22.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96487.1 - 0.00055 20.2 0.1 0.88 10.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX96487.1 - 0.0015 18.9 0.2 0.39 11.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX96487.1 - 0.0031 17.8 0.1 0.0065 16.8 0.1 1.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96488.1 - 0.06 13.9 0.0 6.1 7.5 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) RabGAP-TBC PF00566.18 EAX96489.1 - 9.5e-41 139.8 1.1 1.7e-40 139.0 0.6 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.12 EAX96489.1 - 0.0023 18.1 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Gly_rich PF12810.7 EAX96490.1 - 4.2e-27 95.6 24.5 4.9e-27 95.4 24.5 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank_2 PF12796.7 EAX96492.1 - 1.8e-49 166.3 24.5 4.1e-14 52.9 0.3 5.2 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96492.1 - 3.9e-40 135.7 13.8 6.7e-09 36.1 0.1 8.3 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX96492.1 - 1.2e-35 120.4 7.8 6.7e-07 29.5 0.0 9.0 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EAX96492.1 - 2.5e-34 113.4 9.9 1.3e-06 28.2 0.0 9.5 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX96492.1 - 5.4e-29 99.9 6.5 6.6e-09 35.9 0.0 6.0 2 1 5 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96492.1 - 3.6e-12 46.0 17.4 6.4e-10 38.9 3.4 5.3 3 1 1 5 5 5 2 Domain of unknown function (DUF3447) DUF655 PF04919.12 EAX96492.1 - 0.0073 16.3 0.0 0.75 9.7 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF655) Orn_Arg_deC_N PF02784.16 EAX96492.1 - 0.016 14.6 0.1 0.68 9.3 0.0 2.8 2 1 1 3 3 3 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF3718 PF12514.8 EAX96492.1 - 0.019 15.1 2.5 0.081 13.1 0.1 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3718) Ank_2 PF12796.7 EAX96493.1 - 1.5e-39 134.4 19.9 3.1e-14 53.3 0.5 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96493.1 - 9.9e-35 117.5 7.5 4.7e-05 23.6 0.2 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX96493.1 - 6.1e-33 109.1 11.6 0.00011 22.4 0.1 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX96493.1 - 5.7e-31 106.2 13.1 1.8e-08 34.5 0.4 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX96493.1 - 1.6e-30 105.0 14.9 5.8e-09 36.3 0.2 8.7 3 2 6 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96493.1 - 1.7e-14 53.5 10.3 3.4e-13 49.4 0.7 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) PSP PF04046.16 EAX96496.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96497.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX96498.1 - 0.067 13.7 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX96499.1 - 7.2e-55 182.9 44.7 2.4e-27 94.8 14.2 5.7 4 2 2 6 6 6 3 Phage tail repeat like DUF4116 PF13475.6 EAX96499.1 - 0.037 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Tup_N PF08581.10 EAX96499.1 - 4.8 7.5 7.6 0.39 11.1 1.5 2.4 3 0 0 3 3 3 0 Tup N-terminal Amidase02_C PF12123.8 EAX96500.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX96502.1 - 1.3e-71 240.0 4.4 1.9e-71 239.4 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) PhzC-PhzF PF02567.16 EAX96503.1 - 1.6e-51 175.4 0.0 2.2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Myb_DNA-binding PF00249.31 EAX96507.1 - 3.8e-31 107.0 6.5 2.6e-16 59.5 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96507.1 - 1.7e-24 85.8 6.5 2.5e-14 53.3 0.5 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX96507.1 - 2.3e-11 43.7 3.6 5.4e-05 23.2 0.2 3.1 2 1 2 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 EAX96507.1 - 0.0045 17.2 0.4 0.73 10.1 0.1 2.7 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 RE_TaqI PF09573.10 EAX96507.1 - 0.0062 16.4 1.7 0.011 15.6 1.7 1.4 1 0 0 1 1 1 1 TaqI restriction endonuclease Rap1_C PF11626.8 EAX96507.1 - 0.015 15.3 0.0 0.13 12.4 0.0 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF269 PF03270.13 EAX96507.1 - 0.045 13.9 0.1 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF269 TA_inhibitor PF17574.2 EAX96507.1 - 0.056 13.5 0.2 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) HTH_AsnC-type PF13404.6 EAX96507.1 - 0.15 11.9 0.8 1.9 8.4 0.0 2.9 3 1 0 3 3 3 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_7 PF15963.5 EAX96507.1 - 0.16 11.9 10.1 0.3 11.0 0.2 3.1 1 1 2 3 3 3 0 Myb DNA-binding like Phage_lysozyme2 PF18013.1 EAX96507.1 - 0.28 11.2 3.9 0.73 9.8 3.9 1.7 1 0 0 1 1 1 0 Phage tail lysozyme DUF2508 PF10704.9 EAX96507.1 - 0.68 10.1 9.0 3.3 8.0 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2508) Halogen_Hydrol PF10112.9 EAX96507.1 - 0.88 9.6 5.4 0.38 10.7 1.5 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Myb_DNA-bind_4 PF13837.6 EAX96507.1 - 0.93 9.9 12.0 0.99 9.8 5.4 3.6 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Atg29_N PF18388.1 EAX96507.1 - 1.4 8.8 3.6 24 4.8 0.6 2.6 2 0 0 2 2 2 0 Atg29 N-terminal domain MADF_DNA_bdg PF10545.9 EAX96507.1 - 1.6 9.1 5.7 17 5.8 0.6 3.1 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PolyA_pol_RNAbd PF12627.7 EAX96509.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Metallophos PF00149.28 EAX96510.1 - 1.5e-24 87.7 0.0 2.4e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX96510.1 - 0.023 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_4 PF13637.6 EAX96511.1 - 2.1e-112 366.2 21.3 2.6e-14 53.4 0.0 18.4 8 4 11 19 19 19 16 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96511.1 - 3e-107 351.4 33.9 1.4e-18 67.3 0.4 11.8 3 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX96511.1 - 1.9e-94 308.4 19.2 8e-12 45.2 0.1 15.3 3 3 11 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 EAX96511.1 - 3.9e-92 299.0 25.2 2.3e-05 24.6 0.1 20.4 19 1 0 19 19 19 18 Ankyrin repeat Ank_3 PF13606.6 EAX96511.1 - 7e-91 287.2 31.8 2.3e-05 24.4 0.1 22.4 24 0 0 24 24 24 18 Ankyrin repeat DUF3447 PF11929.8 EAX96511.1 - 2e-23 82.1 6.2 2e-23 82.1 6.2 6.8 7 3 3 10 10 10 1 Domain of unknown function (DUF3447) PEGA PF08308.11 EAX96511.1 - 0.00013 21.8 0.0 3.6 7.5 0.0 4.7 5 0 0 5 5 5 2 PEGA domain Pkinase PF00069.25 EAX96512.1 - 3.7e-66 223.2 0.0 4.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96512.1 - 2.4e-30 105.7 0.0 2.8e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX96512.1 - 0.00066 19.1 0.0 0.0029 17.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX96512.1 - 0.001 17.9 0.0 0.0028 16.5 0.0 1.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EAX96512.1 - 0.0016 17.8 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAX96512.1 - 0.017 14.7 0.2 0.033 13.8 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 EAX96514.1 - 2.5e-40 136.9 0.7 2.4e-11 44.1 0.0 5.5 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96514.1 - 2.2e-28 98.2 5.1 2.9e-08 34.1 0.0 6.3 4 3 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96514.1 - 1.5e-23 82.6 0.3 7e-09 35.8 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96514.1 - 4.2e-23 78.9 0.3 1.6e-05 24.9 0.0 7.7 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EAX96514.1 - 9.5e-18 63.8 0.0 0.00086 19.6 0.1 5.8 5 1 1 6 6 6 3 Ankyrin repeat DUF2406 PF10295.9 EAX96514.1 - 0.045 14.4 0.0 6.7 7.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) FmdA_AmdA PF03069.15 EAX96514.1 - 0.061 12.2 0.0 1.7 7.4 0.0 3.1 4 1 0 5 5 5 0 Acetamidase/Formamidase family Mgr1 PF08602.10 EAX96515.1 - 0.0039 16.1 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit FtsK_SpoIIIE_N PF12538.8 EAX96515.1 - 0.0058 16.8 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 DNA transporter MPDZ_u10 PF16667.5 EAX96515.1 - 6.5 7.7 10.3 0.46 11.4 4.7 2.1 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein LCAT PF02450.15 EAX96516.1 - 6.3e-31 107.9 0.7 3.3e-28 99.0 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EAX96516.1 - 2.7e-05 23.4 0.1 3.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EAX96516.1 - 0.00025 20.4 0.0 0.00054 19.3 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX96516.1 - 0.0012 19.5 0.0 0.0025 18.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAX96516.1 - 0.0014 18.4 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 EAX96516.1 - 0.0039 17.1 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 EAX96516.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EAX96516.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF4144 PF13642.6 EAX96516.1 - 0.014 15.9 0.1 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 protein structure with unknown function Abhydrolase_3 PF07859.13 EAX96516.1 - 0.033 14.1 0.0 0.22 11.3 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 EAX96516.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 EAX96516.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family UPF0227 PF05728.12 EAX96516.1 - 0.071 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) OAD_gamma PF04277.13 EAX96517.1 - 0.043 14.4 2.0 1.9 9.1 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4576 PF15144.6 EAX96517.1 - 0.094 12.6 0.3 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Shisa PF13908.6 EAX96517.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR_5 PF13306.6 EAX96518.1 - 6e-33 113.5 27.3 4.2e-19 68.8 9.9 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96518.1 - 5.8e-07 29.2 0.0 0.34 10.7 0.0 4.3 1 1 6 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAX96518.1 - 1.4e-06 28.5 4.2 0.099 13.1 0.1 3.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) Pentapeptide_4 PF13599.6 EAX96518.1 - 0.0077 16.4 1.4 0.26 11.5 1.4 3.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) FN3_7 PF18447.1 EAX96518.1 - 0.052 13.9 1.7 5.3 7.4 0.9 2.4 2 0 0 2 2 2 0 Fibronectin type III domain LRR_5 PF13306.6 EAX96519.1 - 2.7e-51 172.9 31.7 1.1e-19 70.7 4.9 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96519.1 - 3.4e-11 42.8 1.3 0.0033 17.2 0.1 6.9 6 3 0 6 6 6 3 Leucine rich repeat LRR_5 PF13306.6 EAX96520.1 - 2e-105 347.8 83.5 5.3e-33 113.7 13.1 4.6 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96520.1 - 4.3e-16 58.4 11.1 7.3e-06 25.7 0.3 7.8 4 4 5 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 EAX96520.1 - 0.0018 18.6 21.9 0.77 10.3 1.2 7.5 4 3 3 7 7 7 3 Leucine Rich repeats (2 copies) Myb_DNA-binding PF00249.31 EAX96521.1 - 5.7e-25 87.3 1.2 2.7e-14 53.1 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96521.1 - 5e-23 81.1 5.2 3.1e-18 65.8 0.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96521.1 - 6.7e-07 29.1 2.1 1.8e-05 24.6 0.3 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX96521.1 - 5.7e-05 23.1 0.3 0.047 13.7 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX96521.1 - 0.12 12.7 5.1 0.17 12.3 0.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EAX96521.1 - 2.5 8.2 5.9 42 4.3 0.1 3.5 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain ATG13 PF10033.9 EAX96524.1 - 4.5e-10 39.6 0.3 6.3e-09 35.9 0.2 2.3 1 1 1 2 2 2 1 Autophagy-related protein 13 ToxN_toxin PF13958.6 EAX96524.1 - 0.12 12.6 0.3 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system GATase_3 PF07685.14 EAX96524.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DNA_repr_REX1B PF14966.6 EAX96525.1 - 0.026 15.2 14.8 0.16 12.6 0.3 4.2 3 2 1 5 5 5 0 DNA repair REX1-B LCIB_C_CA PF18599.1 EAX96525.1 - 0.22 10.8 1.4 0.57 9.4 1.2 1.8 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases GTP-bdg_M PF16360.5 EAX96525.1 - 0.37 11.4 4.1 2.5 8.8 0.0 3.7 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region Snapin_Pallidin PF14712.6 EAX96525.1 - 1.3 9.5 15.7 1.9 8.9 4.3 3.8 3 1 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 EAX96525.1 - 1.5 8.8 16.7 17 5.5 0.5 4.7 2 2 3 6 6 6 0 Protein of unknown function (DUF1664) DUF489 PF04356.12 EAX96525.1 - 3.8 7.5 7.5 3.5 7.6 1.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF489) Syntaxin-6_N PF09177.11 EAX96525.1 - 4.6 7.8 25.5 8.3 7.0 0.7 4.9 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Gly_rich PF12810.7 EAX96526.1 - 2.7e-50 171.6 33.3 3.2e-50 171.3 33.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank_2 PF12796.7 EAX96527.1 - 1.4e-48 163.4 0.6 3.1e-13 50.1 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96527.1 - 1.6e-47 159.3 0.0 1e-10 41.9 0.0 5.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96527.1 - 1.6e-32 107.8 0.1 0.00037 20.7 0.0 8.1 8 1 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 EAX96527.1 - 1.7e-32 110.4 0.0 6.4e-06 26.4 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAX96527.1 - 4e-30 103.5 0.0 1.8e-09 37.7 0.0 6.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) DUF5049 PF16468.5 EAX96527.1 - 0.17 11.8 1.2 4.7 7.2 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF5049) APG6_N PF17675.1 EAX96528.1 - 2e-05 25.1 3.4 2e-05 25.1 3.4 1.5 2 0 0 2 2 1 1 Apg6 coiled-coil region Fez1 PF06818.15 EAX96528.1 - 0.0004 20.9 2.4 0.0004 20.9 2.4 1.5 2 0 0 2 2 1 1 Fez1 DUF812 PF05667.11 EAX96528.1 - 0.00049 19.1 3.5 0.00052 19.0 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 EAX96528.1 - 0.0007 19.6 7.6 0.0063 16.5 5.3 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EAX96528.1 - 0.00075 19.9 5.6 0.00075 19.9 5.6 1.7 2 0 0 2 2 1 1 Cell division protein ZapB DivIC PF04977.15 EAX96528.1 - 0.00081 19.1 4.1 0.00081 19.1 4.1 2.8 2 1 1 3 3 2 2 Septum formation initiator LPP PF04728.13 EAX96528.1 - 0.00082 19.7 2.0 0.00082 19.7 2.0 3.0 3 1 0 3 3 2 1 Lipoprotein leucine-zipper HAUS5 PF14817.6 EAX96528.1 - 0.0014 17.5 0.4 0.0014 17.5 0.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 TMF_TATA_bd PF12325.8 EAX96528.1 - 0.0019 18.4 3.9 0.0027 17.9 2.5 1.9 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EAX96528.1 - 0.0024 16.8 4.9 0.0026 16.7 4.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein BRE1 PF08647.11 EAX96528.1 - 0.0028 17.7 7.0 0.0028 17.7 7.0 2.2 3 0 0 3 3 1 1 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 EAX96528.1 - 0.0034 17.6 2.4 0.0059 16.8 2.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Swi5 PF07061.11 EAX96528.1 - 0.0039 17.2 4.7 0.0039 17.2 4.7 2.2 1 1 1 2 2 2 1 Swi5 TPR_MLP1_2 PF07926.12 EAX96528.1 - 0.0057 16.7 4.0 0.012 15.6 4.0 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 EAX96528.1 - 0.0065 16.5 1.9 0.0065 16.5 1.9 2.6 2 1 0 3 3 3 1 Basic region leucine zipper Pox_A_type_inc PF04508.12 EAX96528.1 - 0.007 16.2 1.0 0.17 11.8 0.1 3.3 1 1 2 3 3 3 1 Viral A-type inclusion protein repeat DUF5082 PF16888.5 EAX96528.1 - 0.0076 16.5 11.3 2 8.7 11.4 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 EAX96528.1 - 0.0093 15.5 6.0 0.016 14.7 6.0 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF4094 PF13334.6 EAX96528.1 - 0.0095 16.3 1.3 0.0095 16.3 1.3 2.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4094) DUF3450 PF11932.8 EAX96528.1 - 0.012 15.0 2.6 0.018 14.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 EAX96528.1 - 0.015 15.6 3.7 0.024 14.9 3.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FliJ PF02050.16 EAX96528.1 - 0.018 15.3 3.9 0.041 14.1 3.8 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein DUF4200 PF13863.6 EAX96528.1 - 0.018 15.4 3.7 0.018 15.4 3.7 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) End3 PF12761.7 EAX96528.1 - 0.02 15.1 6.5 0.043 14.0 6.5 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 BST2 PF16716.5 EAX96528.1 - 0.022 15.3 5.9 0.05 14.2 2.0 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF2730 PF10805.8 EAX96528.1 - 0.022 14.8 1.2 0.055 13.6 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 EAX96528.1 - 0.027 14.7 4.8 0.048 13.9 1.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Atg14 PF10186.9 EAX96528.1 - 0.032 13.3 7.2 0.042 12.9 7.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 EAX96528.1 - 0.034 14.9 5.2 0.034 14.9 5.2 1.9 2 1 0 2 2 2 0 Occludin homology domain MIP-T3_C PF17749.1 EAX96528.1 - 0.035 14.1 6.0 0.069 13.1 6.0 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4407 PF14362.6 EAX96528.1 - 0.042 13.2 0.5 0.049 13.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EAX96528.1 - 0.05 13.8 8.9 0.054 13.6 8.1 1.5 1 1 0 1 1 1 0 Tropomyosin like TSC22 PF01166.18 EAX96528.1 - 0.051 13.9 3.3 0.051 13.9 3.3 2.4 2 1 0 2 2 1 0 TSC-22/dip/bun family Spectrin PF00435.21 EAX96528.1 - 0.057 13.9 2.7 0.12 12.9 1.9 1.9 1 1 1 2 2 1 0 Spectrin repeat FlxA PF14282.6 EAX96528.1 - 0.058 13.4 4.7 0.12 12.4 4.7 1.6 1 0 0 1 1 1 0 FlxA-like protein THOC7 PF05615.13 EAX96528.1 - 0.059 13.7 7.9 0.091 13.0 6.3 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Lebercilin PF15619.6 EAX96528.1 - 0.067 12.8 7.3 0.12 12.0 7.3 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4618 PF15397.6 EAX96528.1 - 0.07 12.5 11.1 0.32 10.4 6.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) SseC PF04888.12 EAX96528.1 - 0.076 12.6 2.0 0.083 12.5 2.0 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF724 PF05266.14 EAX96528.1 - 0.079 12.8 7.9 0.09 12.6 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EAX96528.1 - 0.093 12.8 5.1 0.24 11.4 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 EAX96528.1 - 0.098 13.0 9.0 0.14 12.4 8.7 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DASH_Spc19 PF08287.11 EAX96528.1 - 0.11 12.4 6.6 0.18 11.7 2.9 2.2 2 0 0 2 2 2 0 Spc19 Sipho_Gp157 PF05565.11 EAX96528.1 - 0.13 12.2 11.2 0.054 13.5 5.9 2.2 1 1 0 2 2 2 0 Siphovirus Gp157 Cep57_MT_bd PF06657.13 EAX96528.1 - 0.14 12.6 2.2 0.49 10.9 0.5 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HMMR_C PF15908.5 EAX96528.1 - 0.14 12.4 10.3 0.08 13.2 5.4 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF948 PF06103.11 EAX96528.1 - 0.15 12.3 1.0 0.36 11.1 1.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Csm1_N PF18504.1 EAX96528.1 - 0.17 12.3 8.7 0.28 11.5 6.8 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 EAX96528.1 - 0.18 10.3 12.5 0.16 10.6 10.4 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A CEP209_CC5 PF16574.5 EAX96528.1 - 0.19 11.9 6.3 0.4 10.9 6.1 1.7 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 GrpE PF01025.19 EAX96528.1 - 0.23 11.1 11.4 0.14 11.8 6.7 2.4 1 1 2 3 3 3 0 GrpE Seryl_tRNA_N PF02403.22 EAX96528.1 - 0.28 11.4 11.9 0.075 13.3 6.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EAX96528.1 - 0.29 11.2 7.4 1.1 9.3 3.3 2.1 1 1 1 2 2 2 0 Laminin Domain II bZIP_1 PF00170.21 EAX96528.1 - 0.33 11.1 12.1 0.19 11.8 7.1 2.7 2 1 0 2 2 2 0 bZIP transcription factor RILP PF11461.8 EAX96528.1 - 0.36 11.1 7.3 0.089 13.0 2.3 2.4 2 1 1 3 3 2 0 Rab interacting lysosomal protein DUF2203 PF09969.9 EAX96528.1 - 0.45 11.2 2.4 1.1 10.0 1.4 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 EAX96528.1 - 0.45 10.8 10.5 0.081 13.2 5.9 2.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4795 PF16043.5 EAX96528.1 - 0.45 10.1 9.7 0.95 9.0 9.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Prominin PF05478.11 EAX96528.1 - 0.57 8.1 10.2 0.69 7.8 10.2 1.1 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.8 EAX96528.1 - 0.71 9.9 12.1 0.3 11.1 8.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EAX96528.1 - 0.95 9.6 9.9 2.6 8.2 9.9 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 EAX96528.1 - 1.2 9.5 10.2 3.9 7.9 6.8 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1640 PF07798.11 EAX96528.1 - 1.6 8.8 8.6 1.6 8.8 6.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF2205 PF10224.9 EAX96528.1 - 1.7 8.7 9.5 0.68 10.0 5.1 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Ax_dynein_light PF10211.9 EAX96528.1 - 2 8.3 12.1 2.2 8.2 11.1 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain Snapin_Pallidin PF14712.6 EAX96528.1 - 2.2 8.8 7.8 2.1 8.8 5.9 1.9 1 1 1 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.11 EAX96528.1 - 2.2 8.7 8.9 0.7 10.3 1.2 2.8 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 EAX96528.1 - 2.7 8.4 9.5 0.82 10.0 6.3 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF16 PF01519.16 EAX96528.1 - 3.2 8.3 11.3 3.4 8.2 8.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 EAX96528.1 - 3.8 7.7 14.7 0.062 13.5 6.6 2.2 3 0 0 3 3 1 0 Centrosomin N-terminal motif 1 Tup_N PF08581.10 EAX96528.1 - 3.8 7.9 10.9 0.27 11.5 4.3 2.4 3 0 0 3 3 2 0 Tup N-terminal DRIM PF07539.12 EAX96529.1 - 7.6e-05 21.2 0.2 0.00015 20.2 0.2 1.4 1 0 0 1 1 1 1 Down-regulated in metastasis WD40 PF00400.32 EAX96529.1 - 0.0036 18.1 0.0 0.026 15.4 0.0 2.5 2 0 0 2 2 1 1 WD domain, G-beta repeat DrsE_2 PF13686.6 EAX96529.1 - 0.049 13.5 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family ANAPC4_WD40 PF12894.7 EAX96529.1 - 0.059 13.7 0.0 0.96 9.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EAX96529.1 - 0.12 12.3 16.6 0.2 11.5 0.3 4.9 3 2 2 5 5 5 0 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EAX96529.1 - 0.12 12.0 10.6 0.25 11.0 10.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EAX96529.1 - 1.1 9.4 11.2 2.6 8.1 11.2 1.7 1 0 0 1 1 1 0 Zinc-finger Vps39_2 PF10367.9 EAX96529.1 - 1.1 9.7 3.8 1.8 9.1 1.9 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EAX96529.1 - 1.9 8.8 11.4 5.2 7.4 11.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAX96529.1 - 2.2 8.3 12.9 5.6 7.0 12.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAX96529.1 - 2.8 8.1 8.4 11 6.1 5.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAX96529.1 - 5.7 6.9 15.4 2.1 8.3 11.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX96529.1 - 6.7 6.6 10.7 1.4 8.8 6.7 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 EAX96529.1 - 6.8 6.6 9.1 22 5.0 9.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_P_Rpp14 PF01900.19 EAX96530.1 - 6.7e-18 64.8 0.0 7.6e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family Rad1 PF02144.16 EAX96531.1 - 0.017 14.2 0.3 0.021 13.9 0.3 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 Rho_Binding PF08912.11 EAX96531.1 - 0.051 14.4 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Rho Binding CMD PF02627.20 EAX96532.1 - 2e-10 40.6 0.0 2.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family SNARE PF05739.19 EAX96533.1 - 2e-12 46.9 0.2 7.9e-12 45.0 0.2 2.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EAX96533.1 - 5.8e-05 22.9 6.5 0.00013 21.8 6.4 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 ETRAMP PF09716.10 EAX96533.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) COG2 PF06148.11 EAX96533.1 - 0.034 14.2 8.0 0.23 11.5 0.8 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_34 PF13601.6 EAX96533.1 - 0.04 14.1 0.3 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain Sigma_reg_N PF13800.6 EAX96533.1 - 0.05 13.9 1.9 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Tho1_MOS11_C PF18592.1 EAX96533.1 - 0.083 12.7 1.5 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Fusion_gly PF00523.18 EAX96533.1 - 0.18 10.1 4.9 0.06 11.6 0.3 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 Atg14 PF10186.9 EAX96533.1 - 1.7 7.6 9.6 1.6 7.7 7.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pup PF05639.11 EAX96533.1 - 1.8 9.6 0.0 1.8 9.6 0.0 3.2 3 1 0 3 3 3 0 Pup-like protein THOC7 PF05615.13 EAX96533.1 - 2.4 8.5 11.1 10 6.4 3.0 3.5 3 1 0 3 3 3 0 Tho complex subunit 7 Metallophos PF00149.28 EAX96534.1 - 2.1e-26 93.7 0.5 3.1e-26 93.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX96534.1 - 0.0043 17.3 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EAX96534.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Sec8_exocyst PF04048.14 EAX96535.1 - 0.0041 17.0 5.6 0.0041 17.0 5.6 4.0 4 2 0 4 4 4 1 Sec8 exocyst complex component specific domain Img2 PF05046.14 EAX96535.1 - 0.045 14.1 1.6 1.1 9.6 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) GMP_synt_C PF00958.22 EAX96535.1 - 0.049 13.7 0.9 0.26 11.3 0.1 2.5 2 0 0 2 2 2 0 GMP synthase C terminal domain ArsR PF09824.9 EAX96535.1 - 0.18 11.4 13.4 0.29 10.7 2.5 3.3 3 0 0 3 3 3 0 ArsR transcriptional regulator CSTF2_hinge PF14327.6 EAX96535.1 - 0.42 11.1 8.2 1.1 9.7 0.9 3.0 2 1 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 DUF948 PF06103.11 EAX96535.1 - 0.7 10.2 16.6 13 6.2 1.1 5.5 2 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.10 EAX96535.1 - 1.7 8.4 24.0 1.9 8.3 1.2 5.5 5 1 0 5 5 5 0 DASH complex subunit Duo1 FliJ PF02050.16 EAX96535.1 - 1.8 8.8 14.1 3 8.1 0.9 3.6 4 0 0 4 4 4 0 Flagellar FliJ protein Spore_III_AB PF09548.10 EAX96535.1 - 2.2 8.4 10.2 1.1 9.3 0.9 3.1 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Baculo_PEP_C PF04513.12 EAX96535.1 - 2.2 8.3 29.7 9.5 6.3 7.2 4.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CagE_TrbE_VirB PF03135.14 EAX96535.1 - 3.8 7.6 16.2 2.7 8.0 3.7 2.9 2 1 0 3 3 3 0 CagE, TrbE, VirB family, component of type IV transporter system KxDL PF10241.9 EAX96535.1 - 3.9 7.8 22.2 3.9 7.8 0.2 5.3 4 1 2 6 6 6 0 Uncharacterized conserved protein Nup54 PF13874.6 EAX96535.1 - 5.4 7.1 16.2 44 4.2 7.7 4.0 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 ApbE PF02424.15 EAX96535.1 - 7.2 6.0 11.1 14 5.1 1.0 2.9 1 1 1 2 2 2 0 ApbE family TMPIT PF07851.13 EAX96535.1 - 7.4 5.7 25.6 0.6 9.3 7.0 3.3 2 1 0 3 3 3 0 TMPIT-like protein GTP-bdg_M PF16360.5 EAX96535.1 - 8.7 7.0 9.4 0.51 11.0 0.4 3.4 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region DUF1664 PF07889.12 EAX96536.1 - 0.00066 19.7 17.4 0.04 14.0 8.8 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EAX96536.1 - 0.0015 18.8 19.6 0.055 13.9 4.3 4.9 2 1 3 5 5 5 2 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EAX96536.1 - 0.0098 15.9 18.9 0.09 12.8 5.2 2.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 EAX96536.1 - 0.012 15.9 15.2 0.12 12.7 3.6 2.4 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EzrA PF06160.12 EAX96536.1 - 0.014 13.6 22.7 0.13 10.4 8.8 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4795 PF16043.5 EAX96536.1 - 0.017 14.8 22.9 0.036 13.7 23.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Tropomyosin_1 PF12718.7 EAX96536.1 - 0.024 14.8 21.6 0.097 12.8 11.8 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF4482 PF14818.6 EAX96536.1 - 0.036 14.9 5.1 0.036 14.9 5.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Med9 PF07544.13 EAX96536.1 - 0.041 14.0 12.0 0.48 10.6 2.7 3.4 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 EAX96536.1 - 0.042 14.2 21.3 0.19 12.0 1.6 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAIN_A PF18619.1 EAX96536.1 - 0.042 14.0 0.7 10 6.4 0.1 2.6 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Syntaxin-6_N PF09177.11 EAX96536.1 - 0.055 14.0 11.9 14 6.3 11.9 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal MitMem_reg PF13012.6 EAX96536.1 - 0.059 13.8 11.5 0.073 13.5 2.7 2.7 1 1 2 3 3 2 0 Maintenance of mitochondrial structure and function FliJ PF02050.16 EAX96536.1 - 0.068 13.4 13.9 0.03 14.5 4.5 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein FapA PF03961.13 EAX96536.1 - 0.068 11.8 22.5 0.11 11.1 4.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ISG65-75 PF11727.8 EAX96536.1 - 0.079 12.2 12.9 0.084 12.1 5.4 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein RNAse_A_bac PF18431.1 EAX96536.1 - 0.09 13.7 2.3 0.092 13.7 0.9 1.8 2 1 0 2 2 1 0 Bacterial CdiA-CT RNAse A domain CENP-F_leu_zip PF10473.9 EAX96536.1 - 0.1 12.6 21.9 0.077 13.0 12.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 EAX96536.1 - 0.2 12.3 10.2 0.57 10.8 1.3 3.8 2 1 2 4 4 4 0 SlyX Focal_AT PF03623.13 EAX96536.1 - 0.31 11.1 13.2 0.041 13.9 3.0 2.3 1 1 1 2 2 2 0 Focal adhesion targeting region TraF_2 PF13729.6 EAX96536.1 - 0.32 10.3 8.8 2.6 7.3 5.2 2.5 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Fib_alpha PF08702.10 EAX96536.1 - 0.43 10.7 23.5 2.6 8.2 6.5 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 EAX96536.1 - 0.49 10.5 16.5 8.2 6.5 8.0 3.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 EAX96536.1 - 0.53 8.1 20.3 1.3 6.9 5.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.13 EAX96536.1 - 0.53 10.2 18.4 0.2 11.6 2.8 2.4 1 1 1 2 2 2 0 Aphid transmission protein Spore_III_AB PF09548.10 EAX96536.1 - 0.79 9.8 10.3 1.3 9.2 10.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Rx_N PF18052.1 EAX96536.1 - 0.88 9.9 8.8 9.6 6.6 0.9 3.1 1 1 2 3 3 3 0 Rx N-terminal domain Snapin_Pallidin PF14712.6 EAX96536.1 - 0.92 10.0 17.6 1.9 9.0 2.1 3.4 1 1 2 3 3 3 0 Snapin/Pallidin Fzo_mitofusin PF04799.13 EAX96536.1 - 0.93 9.0 15.3 0.79 9.2 6.2 2.9 1 1 1 2 2 2 0 fzo-like conserved region TBCC_N PF16752.5 EAX96536.1 - 0.96 9.9 13.4 0.14 12.6 3.8 2.7 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain P4Ha_N PF08336.11 EAX96536.1 - 1.4 8.9 15.7 8.6 6.4 8.8 2.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Exonuc_VII_L PF02601.15 EAX96536.1 - 1.5 8.4 14.8 5.6 6.4 14.8 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 EAX96536.1 - 1.5 9.0 18.4 0.4 10.9 12.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Muted PF14942.6 EAX96536.1 - 2.2 8.6 26.2 0.3 11.4 4.3 2.8 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF745 PF05335.13 EAX96536.1 - 2.3 7.9 13.4 2.8 7.6 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) EMP24_GP25L PF01105.24 EAX96536.1 - 3.3 7.6 16.7 0.6 10.0 2.5 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4404 PF14357.6 EAX96536.1 - 3.4 8.4 9.6 2.2 9.0 1.8 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4404) DUF2175 PF09943.9 EAX96536.1 - 3.5 8.0 11.4 1 9.7 1.2 3.1 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) XhlA PF10779.9 EAX96536.1 - 3.5 7.9 25.9 3.2 8.0 0.2 4.3 2 2 2 4 4 4 0 Haemolysin XhlA CHDCT2 PF08074.11 EAX96536.1 - 4.8 7.3 12.2 2 8.6 0.8 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain BCDHK_Adom3 PF10436.9 EAX96536.1 - 6 6.7 13.4 1.1 9.1 0.4 2.4 1 1 1 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fez1 PF06818.15 EAX96536.1 - 7.5 7.0 17.2 75 3.7 17.2 2.1 1 1 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 EAX96536.1 - 8.9 6.5 15.5 1.5 9.0 4.5 3.7 2 1 2 4 4 4 0 bZIP transcription factor dNK PF01712.19 EAX96537.1 - 0.0007 19.5 0.5 0.49 10.2 0.0 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EAX96537.1 - 0.0021 18.1 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 EAX96537.1 - 0.0042 16.8 1.5 0.078 12.7 0.2 2.2 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EAX96537.1 - 0.014 16.0 0.1 0.022 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX96537.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAX96537.1 - 0.082 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 EAX96537.1 - 0.084 12.5 0.1 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.12 EAX96537.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 EAX96537.1 - 0.12 12.4 0.4 1.7 8.6 0.4 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX96537.1 - 0.2 12.2 0.4 0.21 12.1 0.4 1.4 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.25 EAX96538.1 - 3.6e-19 69.1 0.2 4.8e-19 68.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96538.1 - 4e-10 39.4 0.5 2.5e-08 33.6 0.5 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX96538.1 - 0.023 14.6 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX96538.1 - 0.056 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CHD5 PF04420.14 EAX96538.1 - 0.13 12.1 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 CHD5-like protein DUF3447 PF11929.8 EAX96539.1 - 3.7e-09 36.4 1.0 4e-09 36.3 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) SEN1_N PF12726.7 EAX96540.1 - 0.069 11.4 2.8 0.041 12.1 0.4 1.8 2 0 0 2 2 2 0 SEN1 N terminal Barstar PF01337.18 EAX96540.1 - 0.087 12.9 0.3 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) EIIA-man PF03610.16 EAX96540.1 - 0.12 12.6 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 PTS system fructose IIA component ArfGap PF01412.18 EAX96541.1 - 3.7e-33 114.1 1.4 3.7e-33 114.1 1.4 2.8 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EAX96541.1 - 9.6e-18 64.8 3.2 1.6e-17 64.1 3.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EAX96541.1 - 5.8e-17 62.1 0.8 1.1e-16 61.2 0.8 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EAX96541.1 - 1.1e-07 32.0 0.8 4.2e-06 27.0 0.3 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_5 PF13857.6 EAX96541.1 - 0.00014 22.1 0.2 0.00043 20.5 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_11 PF15413.6 EAX96541.1 - 0.0013 19.2 7.1 0.018 15.5 7.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.7 EAX96541.1 - 0.0018 18.8 0.1 0.024 15.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BAR PF03114.18 EAX96541.1 - 0.018 14.7 0.5 0.031 13.9 0.5 1.4 1 0 0 1 1 1 0 BAR domain Tom37 PF10568.9 EAX96541.1 - 0.092 13.0 0.2 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein PNP_UDP_1 PF01048.20 EAX96542.1 - 8.8e-38 129.9 0.0 1e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3243 PF11588.8 EAX96543.1 - 0.00051 20.3 1.2 0.066 13.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3243) PilJ PF13675.6 EAX96543.1 - 0.0031 17.5 8.5 2.7 8.1 0.5 4.4 4 1 1 5 5 5 2 Type IV pili methyl-accepting chemotaxis transducer N-term RmuC PF02646.16 EAX96543.1 - 0.0034 16.6 0.8 0.0034 16.6 0.8 3.9 4 1 1 5 5 5 1 RmuC family Tropomyosin_1 PF12718.7 EAX96543.1 - 0.012 15.8 1.2 0.012 15.8 1.2 4.4 4 1 1 5 5 5 0 Tropomyosin like Flagellin_N PF00669.20 EAX96543.1 - 0.032 14.3 0.0 0.032 14.3 0.0 3.8 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF4407 PF14362.6 EAX96543.1 - 0.1 11.9 13.7 0.25 10.6 11.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 EAX96543.1 - 0.32 10.9 0.0 0.32 10.9 0.0 4.9 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Matrilin_ccoil PF10393.9 EAX96543.1 - 1.4 8.8 7.2 3.2 7.7 0.1 3.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 EAX96543.1 - 3.1 8.3 15.3 2.1 8.9 0.1 4.5 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein SpecificRecomb PF10136.9 EAX96543.1 - 3.9 5.7 8.5 5.7 5.1 0.3 2.7 2 1 0 2 2 2 0 Site-specific recombinase DUF1664 PF07889.12 EAX96543.1 - 4 7.5 14.4 16 5.6 0.2 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) YqgF PF14639.6 EAX96543.1 - 4.4 7.1 9.4 1.1 9.0 0.3 3.3 2 1 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 DUF641 PF04859.12 EAX96543.1 - 4.6 7.6 20.2 0.18 12.1 1.8 4.2 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Wtap PF17098.5 EAX96543.1 - 7.3 6.5 23.7 0.93 9.4 0.6 4.4 3 1 0 3 3 2 0 WTAP/Mum2p family Fez1 PF06818.15 EAX96543.1 - 9.7 6.6 28.0 4.4 7.7 11.0 3.1 1 1 2 3 3 3 0 Fez1 14-3-3 PF00244.20 EAX96544.1 - 7.7e-63 212.0 0.0 1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EAX96544.1 - 0.0019 18.5 1.3 1.7 9.0 2.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX96544.1 - 0.071 13.3 4.1 19 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EAX96545.1 - 1e-15 58.0 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX96545.1 - 1.7e-14 54.3 0.0 2.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX96545.1 - 1.9e-14 54.2 0.0 2.5e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX96545.1 - 8.6e-13 48.8 0.0 1.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX96545.1 - 1.9e-11 44.0 0.1 2.4e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAX96545.1 - 3.2e-10 39.8 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EAX96545.1 - 2.8e-08 33.5 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 EAX96545.1 - 5.5e-05 22.6 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.20 EAX96545.1 - 6e-05 22.2 0.0 7.8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 EAX96545.1 - 0.00012 21.5 0.2 0.00023 20.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EAX96545.1 - 0.00014 21.5 0.0 0.00037 20.1 0.0 1.7 1 1 1 2 2 2 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EAX96545.1 - 0.00075 18.9 0.0 0.00097 18.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EAX96545.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 EAX96545.1 - 0.046 13.4 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EAX96545.1 - 0.059 12.8 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EAX96545.1 - 0.083 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 EAX96545.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 EAX96545.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain VPS9 PF02204.18 EAX96549.1 - 0.0087 16.3 0.7 0.068 13.4 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain DUF1087 PF06465.13 EAX96549.1 - 0.038 14.0 0.3 0.081 13.0 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF1438 PF07270.11 EAX96549.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) DUF4107 PF13389.6 EAX96552.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pkinase PF00069.25 EAX96554.1 - 1.2e-41 142.9 0.0 2.2e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96554.1 - 2.3e-19 69.7 0.0 4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96554.1 - 6.5e-05 22.4 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX96554.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX96554.1 - 0.025 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EAX96554.1 - 0.05 13.2 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AbrB_C PF18277.1 EAX96554.1 - 0.086 12.5 0.1 0.086 12.5 0.1 2.0 2 0 0 2 2 2 0 AbrB C-terminal domain LRR_5 PF13306.6 EAX96556.1 - 2.5e-65 218.2 39.1 6.7e-27 94.0 11.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96556.1 - 1.8e-17 62.9 1.2 0.023 14.5 0.1 7.6 3 2 5 8 8 8 6 Leucine rich repeat DUF3262 PF11660.8 EAX96556.1 - 0.032 14.6 0.1 0.1 13.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) LRR_4 PF12799.7 EAX96556.1 - 0.073 13.5 12.3 9.4 6.8 0.7 6.3 2 2 3 7 7 7 0 Leucine Rich repeats (2 copies) Plasmid_parti PF01672.16 EAX96556.1 - 0.086 13.5 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 Putative plasmid partition protein DUF3951 PF13131.6 EAX96556.1 - 0.098 12.9 0.5 0.27 11.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Wzz PF02706.15 EAX96556.1 - 0.11 12.9 0.5 0.25 11.6 0.5 1.7 1 0 0 1 1 1 0 Chain length determinant protein Pentapeptide_4 PF13599.6 EAX96556.1 - 7.1 6.9 8.1 0.91 9.7 0.3 3.4 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) Importin_rep_4 PF18808.1 EAX96557.1 - 0.00047 20.4 2.3 0.087 13.1 0.6 3.0 2 0 0 2 2 2 2 Importin repeat Dopey_N PF04118.14 EAX96557.1 - 0.0034 16.6 2.0 0.36 9.9 0.0 3.0 2 0 0 2 2 2 2 Dopey, N-terminal HEAT_2 PF13646.6 EAX96557.1 - 0.0055 17.1 0.1 0.98 9.8 0.0 4.0 4 1 1 5 5 5 1 HEAT repeats Telomere_reg-2 PF10193.9 EAX96557.1 - 0.52 10.8 9.0 3 8.3 0.0 5.2 5 2 0 5 5 5 0 Telomere length regulation protein FANCI_S2 PF14676.6 EAX96557.1 - 1.4 9.2 18.8 1.8 8.8 0.0 5.8 5 2 1 6 6 6 0 FANCI solenoid 2 Cys_Met_Meta_PP PF01053.20 EAX96558.1 - 3.8e-162 539.2 0.0 4.3e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EAX96558.1 - 6.1e-08 31.6 0.3 1.9e-07 30.0 0.3 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 EAX96558.1 - 7.3e-08 31.8 0.4 9.6e-08 31.4 0.4 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAX96558.1 - 1.8e-05 24.1 0.1 2.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EAX96558.1 - 0.0012 17.8 0.1 0.0016 17.4 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein PLC-beta_C PF08703.10 EAX96559.1 - 0.0029 17.6 0.4 0.0038 17.2 0.4 1.2 1 0 0 1 1 1 1 PLC-beta C terminal MULE PF10551.9 EAX96560.1 - 2.7e-10 40.5 0.2 6.2e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX96560.1 - 0.006 15.5 0.2 0.0095 14.8 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX96560.1 - 0.0061 16.3 0.3 0.034 13.8 0.2 1.9 1 1 1 2 2 2 1 Transposase Vta1 PF04652.16 EAX96560.1 - 0.068 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Vta1 like DUF2730 PF10805.8 EAX96561.1 - 0.0028 17.7 0.1 0.0061 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 EAX96561.1 - 0.01 16.1 0.6 0.024 14.9 0.6 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EAX96561.1 - 0.012 15.6 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 EAX96561.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Lip_prot_lig_C PF10437.9 EAX96561.1 - 0.07 13.1 0.2 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus SlyX PF04102.12 EAX96561.1 - 0.097 13.3 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 SlyX DUF2095 PF09868.9 EAX96561.1 - 0.13 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) XhlA PF10779.9 EAX96561.1 - 0.14 12.4 2.4 0.29 11.4 2.4 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Bac_GDH PF05088.12 EAX96562.1 - 0.008 13.7 6.3 0.0038 14.8 4.3 1.4 1 1 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase DUF936 PF06075.12 EAX96562.1 - 1.2 8.0 18.8 2.5 6.9 18.8 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF936) Sec62 PF03839.16 EAX96562.1 - 1.4 8.4 11.1 8.9 5.8 8.1 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 FAM76 PF16046.5 EAX96562.1 - 1.7 7.9 18.0 0.052 12.9 10.6 1.8 2 0 0 2 2 2 0 FAM76 protein ATP-synt_DE PF00401.20 EAX96562.1 - 1.9 8.8 8.1 44 4.4 5.3 2.9 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DNA_pol_A_exo1 PF01612.20 EAX96563.1 - 6.1e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF3584 PF12128.8 EAX96564.1 - 0.0036 14.9 9.0 0.0048 14.5 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) COG2 PF06148.11 EAX96564.1 - 0.014 15.5 5.1 0.027 14.6 5.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Vip3A_N PF12495.8 EAX96564.1 - 0.015 15.2 1.8 0.035 14.0 1.8 1.6 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Laminin_II PF06009.12 EAX96564.1 - 0.035 14.1 4.8 0.088 12.8 4.8 1.7 1 0 0 1 1 1 0 Laminin Domain II KinB_sensor PF16767.5 EAX96564.1 - 0.05 14.1 1.6 0.12 12.9 1.6 1.6 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Rootletin PF15035.6 EAX96564.1 - 0.64 10.0 8.0 1.1 9.3 8.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 EAX96564.1 - 0.87 10.3 3.7 2.6 8.7 3.7 1.8 1 0 0 1 1 1 0 Initiation control protein YabA DHR10 PF18595.1 EAX96564.1 - 1.2 9.2 8.1 2.5 8.2 8.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Baculo_p24 PF05073.12 EAX96564.1 - 1.4 8.7 7.5 1.4 8.7 6.1 1.7 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF2533 PF10752.9 EAX96564.1 - 1.5 9.3 13.1 4 7.9 3.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) Baculo_PEP_C PF04513.12 EAX96564.1 - 7.4 6.6 13.2 0.12 12.4 1.6 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 EAX96568.1 - 1.6e-15 57.2 10.7 0.00017 22.3 0.1 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX96568.1 - 0.00083 19.6 0.0 34 4.8 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EAX96568.1 - 0.019 14.9 0.8 0.72 9.9 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.6 EAX96568.1 - 0.058 13.0 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain DUF563 PF04577.14 EAX96569.1 - 2.6e-38 132.3 0.7 3.7e-38 131.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PTR PF12789.7 EAX96572.1 - 4.8e-60 199.5 39.0 3.6e-34 116.6 15.4 5.8 5 1 2 7 7 7 3 Phage tail repeat like RACo_linker PF17650.1 EAX96572.1 - 0.088 12.7 0.1 1.4 8.8 0.1 2.7 2 1 1 3 3 3 0 RACo linker region HIP1_clath_bdg PF16515.5 EAX96572.1 - 2.9 8.5 7.2 6.5 7.4 2.2 2.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1493 PF07377.12 EAX96573.1 - 0.047 14.2 0.6 0.11 12.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX96574.1 - 0.038 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96575.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Guanylate_cyc PF00211.20 EAX96578.1 - 3.1e-40 137.8 0.0 7e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX96578.1 - 5.5e-09 36.2 0.4 1.6e-08 34.7 0.4 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX96578.1 - 7e-06 26.0 0.2 2.2e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX96578.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX96578.1 - 0.009 15.5 0.5 0.019 14.4 0.5 1.5 1 0 0 1 1 1 1 Heme NO binding associated WD40 PF00400.32 EAX96579.1 - 2.9e-08 34.2 0.6 0.95 10.5 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Frtz PF11768.8 EAX96579.1 - 0.0022 16.4 0.0 0.0041 15.5 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Pectate_lyase22 PF14583.6 EAX96579.1 - 0.0032 16.2 0.1 0.23 10.1 0.0 2.4 2 0 0 2 2 2 2 Oligogalacturonate lyase PQQ_3 PF13570.6 EAX96579.1 - 0.0038 17.7 0.3 0.46 11.1 0.0 4.0 5 0 0 5 5 5 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EAX96579.1 - 0.0065 16.8 0.0 0.35 11.2 0.0 3.0 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Late_protein_L1 PF00500.18 EAX96579.1 - 0.088 11.6 0.1 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 L1 (late) protein PDEase_I PF00233.19 EAX96580.1 - 2.3e-49 168.3 5.2 2.8e-48 164.7 2.0 2.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX96580.1 - 7.4e-11 42.8 0.0 0.00014 22.5 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 EAX96580.1 - 8.6e-06 26.1 0.0 9.1e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 GAF domain HD PF01966.22 EAX96580.1 - 0.0033 17.6 0.0 0.019 15.2 0.0 2.4 1 0 0 1 1 1 1 HD domain DUF3958 PF13125.6 EAX96580.1 - 0.0043 17.2 4.0 0.026 14.7 1.4 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3958) Atx10homo_assoc PF09759.9 EAX96580.1 - 0.24 11.4 3.0 27 4.8 0.1 3.9 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain SlyX PF04102.12 EAX96580.1 - 0.61 10.8 5.6 0.37 11.5 1.9 2.4 2 0 0 2 2 2 0 SlyX Iron_permease PF04120.12 EAX96580.1 - 2.5 7.9 6.2 1.6 8.5 1.9 2.6 2 0 0 2 2 2 0 Low affinity iron permease APG6_N PF17675.1 EAX96580.1 - 7.1 7.2 9.7 20 5.7 3.9 3.0 2 0 0 2 2 2 0 Apg6 coiled-coil region SGT1 PF07093.11 EAX96581.1 - 2.2e-05 23.1 22.7 0.0017 16.9 0.1 3.6 2 2 1 3 3 3 3 SGT1 protein OTCace PF00185.24 EAX96581.1 - 0.0005 20.2 0.1 0.00098 19.2 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Tweety PF04906.13 EAX96582.1 - 5.3e-06 25.4 3.9 2.7e-05 23.0 1.2 2.2 2 0 0 2 2 2 1 Tweety DUF2207 PF09972.9 EAX96582.1 - 0.00019 20.4 0.8 0.00019 20.4 0.8 3.7 3 2 0 3 3 3 2 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 EAX96582.1 - 0.0049 16.9 0.0 0.82 9.8 0.0 3.5 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF1351 PF07083.11 EAX96582.1 - 0.013 15.3 2.8 0.11 12.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) DUF1664 PF07889.12 EAX96582.1 - 0.036 14.1 1.2 4.9 7.2 0.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Phage_holin_3_6 PF07332.11 EAX96582.1 - 0.047 13.7 0.1 0.047 13.7 0.1 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pox_EPC_I2-L1 PF12575.8 EAX96582.1 - 0.094 13.0 4.5 0.61 10.3 4.5 2.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 PhaP_Bmeg PF09602.10 EAX96582.1 - 0.2 11.6 1.5 0.47 10.4 0.3 2.2 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cauli_AT PF03233.13 EAX96582.1 - 0.45 10.4 7.1 0.23 11.4 0.2 2.8 2 1 0 2 2 2 0 Aphid transmission protein ECSCR PF15820.5 EAX96582.1 - 0.6 10.0 5.2 0.36 10.7 0.2 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Rax2 PF12768.7 EAX96582.1 - 1.2 8.5 8.0 0.13 11.7 1.4 2.4 3 0 0 3 3 3 0 Cortical protein marker for cell polarity MtrF PF09472.10 EAX96582.1 - 1.3 8.4 4.5 25 4.4 1.6 3.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MIG-14_Wnt-bd PF06664.12 EAX96582.1 - 3.8 6.6 16.7 0.094 11.9 4.0 2.9 3 0 0 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF1542 PF07564.11 EAX96582.1 - 4.4 7.5 10.2 1.5 9.0 2.9 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Chitin_bind_4 PF00379.23 EAX96583.1 - 0.028 14.9 1.0 0.17 12.4 0.0 2.6 3 0 0 3 3 3 0 Insect cuticle protein EF-hand_1 PF00036.32 EAX96584.1 - 3.3e-22 76.3 10.2 4e-07 29.1 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX96584.1 - 3.8e-20 72.1 8.7 1e-12 48.3 4.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX96584.1 - 5.8e-20 69.5 8.1 2e-05 24.1 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAX96584.1 - 1.2e-11 43.5 13.9 1.7e-05 24.1 0.5 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EAX96584.1 - 1e-06 28.5 9.5 0.00036 20.3 0.5 3.6 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAX96584.1 - 2.6e-05 24.5 4.5 0.0032 17.8 0.2 3.0 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAX96584.1 - 0.011 15.7 6.7 0.23 11.4 0.3 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand QLQ PF08880.11 EAX96584.1 - 0.049 13.4 3.3 0.083 12.7 3.3 1.3 1 0 0 1 1 1 0 QLQ Excalibur PF05901.11 EAX96584.1 - 0.058 14.0 0.8 13 6.5 0.0 3.1 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_10 PF14788.6 EAX96584.1 - 0.092 12.6 2.7 14 5.6 0.1 3.3 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 EAX96584.1 - 0.15 11.9 0.8 34 4.3 0.1 3.0 1 1 1 3 3 3 0 Caleosin related protein Meiosis_expr PF15163.6 EAX96585.1 - 0.024 15.3 1.0 0.024 15.3 1.0 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX96585.1 - 6.1 6.8 13.2 0.18 11.7 2.9 3.0 4 0 0 4 4 4 0 Spo12 family Pox_A32 PF04665.12 EAX96586.1 - 0.00011 21.7 4.3 0.00025 20.6 4.3 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein Y_phosphatase2 PF03162.13 EAX96586.1 - 0.0064 16.1 0.3 0.013 15.1 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family tRNA_synt_1c_R1 PF04558.15 EAX96586.1 - 0.0081 16.2 1.4 0.013 15.5 0.1 1.9 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX96586.1 - 0.05 12.8 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX96586.1 - 0.069 13.4 1.5 0.17 12.2 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) DegT_DnrJ_EryC1 PF01041.17 EAX96588.1 - 6.5e-63 213.2 0.0 7.5e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EAX96588.1 - 0.00041 19.7 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EAX96588.1 - 0.018 13.6 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF5487 PF17589.2 EAX96588.1 - 0.094 13.0 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5487) PALP PF00291.25 EAX96588.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FHA PF00498.26 EAX96590.1 - 0.00014 22.2 0.1 0.00043 20.6 0.1 1.9 1 1 0 1 1 1 1 FHA domain Ras PF00071.22 EAX96591.1 - 1.9e-33 115.4 0.1 2.4e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96591.1 - 9.1e-27 93.7 0.1 1.4e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96591.1 - 2.2e-09 37.0 0.0 3.1e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX96591.1 - 3e-09 36.7 0.2 4.8e-08 32.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX96591.1 - 2.6e-07 30.7 0.3 0.00029 20.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX96591.1 - 1.8e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX96591.1 - 0.0058 16.1 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAX96591.1 - 0.0097 15.3 0.1 0.02 14.2 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MICSWaP PF17018.5 EAX96591.1 - 0.012 15.1 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Spore wall protein PduV-EutP PF10662.9 EAX96591.1 - 0.025 14.3 0.1 0.2 11.4 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EAX96591.1 - 0.12 12.4 1.0 2.8 8.0 0.2 2.3 1 1 1 2 2 2 0 Dynamin family DUF3666 PF12408.8 EAX96591.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Thioredoxin PF00085.20 EAX96593.1 - 1e-11 44.7 0.4 2.5e-11 43.5 0.4 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 EAX96593.1 - 8.7e-10 38.8 8.4 1.6e-06 28.2 2.9 2.4 1 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAX96593.1 - 0.017 15.3 0.1 0.063 13.5 0.2 1.8 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX96593.1 - 0.028 14.9 2.5 0.048 14.1 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin-like domain Orthopox_A47 PF06334.11 EAX96593.1 - 0.034 13.4 2.1 0.045 13.0 0.8 1.7 1 1 1 2 2 2 0 Orthopoxvirus A47 protein Thioredoxin_8 PF13905.6 EAX96593.1 - 0.04 14.2 0.4 0.42 11.0 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_4 PF13462.6 EAX96593.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin Helicase_C PF00271.31 EAX96594.1 - 0.061 13.7 0.0 0.26 11.6 0.0 2.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.6 EAX96594.1 - 1.3 8.9 7.1 0.53 10.2 0.9 3.0 3 1 0 3 3 3 0 rRNA-processing arch domain Chlam_PMP PF02415.17 EAX96596.1 - 6.7 7.4 23.3 1.6 9.4 0.1 6.0 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HEAT PF02985.22 EAX96597.1 - 0.13 12.6 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat ubiquitin PF00240.23 EAX96599.1 - 1.7e-31 107.7 0.1 4.7e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAX96599.1 - 4.2e-12 45.7 1.2 6.2e-07 29.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX96599.1 - 0.00042 20.6 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EAX96599.1 - 0.00081 19.8 4.3 0.027 14.9 0.1 3.7 3 2 0 3 3 3 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX96599.1 - 0.0068 16.5 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX96599.1 - 0.12 12.9 0.0 8.7 7.0 0.0 2.5 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Peptidase_C2 PF00648.21 EAX96600.1 - 8.4e-11 41.4 0.0 3.1e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease Shisa PF13908.6 EAX96601.1 - 0.009 16.3 0.3 0.009 16.3 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4972 PF16342.5 EAX96601.1 - 0.12 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) MFS_2 PF13347.6 EAX96601.1 - 0.19 10.2 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein ApbA_C PF08546.11 EAX96602.1 - 0.078 13.2 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF5621 PF18532.1 EAX96602.1 - 0.1 12.5 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) Fes1 PF08609.10 EAX96602.1 - 0.86 10.5 2.8 3.1 8.7 2.8 2.0 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF5601 PF18151.1 EAX96602.1 - 0.99 9.8 4.9 15 6.0 0.4 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) CelTOS PF18659.1 EAX96602.1 - 2.8 8.4 4.8 1.9 9.0 0.3 3.0 3 1 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites DUF4625 PF15418.6 EAX96603.1 - 0.031 14.5 1.0 0.22 11.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4625) ubiquitin PF00240.23 EAX96604.1 - 1.6e-22 79.1 0.6 2.8e-22 78.2 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX96604.1 - 3.7e-13 49.1 1.4 7.7e-13 48.1 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX96604.1 - 0.0051 17.2 1.4 0.02 15.3 0.3 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX96604.1 - 0.031 14.6 0.3 0.059 13.7 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain FKBP_C PF00254.28 EAX96606.1 - 6.9e-21 74.4 0.0 1.8e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Atg14 PF10186.9 EAX96606.1 - 0.0027 16.9 8.7 0.0046 16.1 8.7 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 EAX96606.1 - 0.025 12.5 4.1 0.038 12.0 3.6 1.5 1 1 0 1 1 1 0 Prominin VID27_PH PF17747.1 EAX96606.1 - 0.042 14.1 0.2 0.093 13.0 0.2 1.6 1 0 0 1 1 1 0 VID27 PH-like domain Cnn_1N PF07989.11 EAX96606.1 - 0.15 12.3 14.1 2.2 8.5 3.5 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 MutS_III PF05192.18 EAX96606.1 - 0.37 11.0 4.4 0.6 10.3 4.4 1.4 1 0 0 1 1 1 0 MutS domain III SPX PF03105.19 EAX96606.1 - 0.53 10.1 15.3 0.79 9.6 15.3 1.1 1 0 0 1 1 1 0 SPX domain APC_N_CC PF16689.5 EAX96606.1 - 0.78 9.8 6.6 0.99 9.5 4.9 2.0 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Efg1 PF10153.9 EAX96606.1 - 3.2 8.2 10.9 51 4.3 11.0 2.4 1 1 0 1 1 1 0 rRNA-processing protein Efg1 Fzo_mitofusin PF04799.13 EAX96606.1 - 4 7.0 12.5 0.38 10.3 1.2 3.1 1 1 2 3 3 3 0 fzo-like conserved region YabA PF06156.13 EAX96606.1 - 4.1 8.1 7.8 3.1 8.5 4.6 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 EAX96606.1 - 8.2 6.8 15.7 1.6e+03 -0.6 15.4 2.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region S_4TM PF18159.1 EAX96606.1 - 9 5.5 6.6 4.6 6.5 2.2 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain LCAT PF02450.15 EAX96607.1 - 8.5e-30 104.2 0.1 2.1e-28 99.6 0.1 2.3 2 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EAX96607.1 - 5e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EAX96607.1 - 9.6e-06 25.4 1.0 3.2e-05 23.7 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX96607.1 - 1.1e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EAX96607.1 - 2.4e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EAX96607.1 - 7.6e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1749 PF08538.10 EAX96607.1 - 0.00038 19.6 0.0 0.00057 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) BAAT_C PF08840.11 EAX96607.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EAX96607.1 - 0.0017 19.0 0.0 0.0025 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EAX96607.1 - 0.0067 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase FSH1 PF03959.13 EAX96607.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1350 PF07082.11 EAX96607.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Choline_transpo PF04515.12 EAX96608.1 - 3.1e-93 312.5 33.8 3.1e-93 312.5 33.8 3.4 2 1 1 3 3 3 1 Plasma-membrane choline transporter Stevor PF17410.2 EAX96608.1 - 0.0086 15.7 0.2 0.026 14.1 0.2 1.8 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 EAX96608.1 - 0.19 12.0 2.6 0.92 9.8 0.3 3.1 3 0 0 3 3 3 0 Orf78 (ac78) LRR19-TM PF15176.6 EAX96608.1 - 9 6.4 16.3 0.31 11.1 3.0 4.0 4 0 0 4 4 4 0 Leucine-rich repeat family 19 TM domain TPR_2 PF07719.17 EAX96609.1 - 1.3e-09 37.5 8.4 0.00016 21.5 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX96609.1 - 8.1e-09 35.0 0.4 4.2e-06 26.3 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EAX96609.1 - 2.6e-08 33.7 1.0 0.00055 20.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX96609.1 - 1e-07 31.5 8.1 0.00041 20.0 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX96609.1 - 4.7e-06 27.2 2.8 0.0076 16.9 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat RPAP3_C PF13877.6 EAX96609.1 - 0.00025 21.5 0.1 0.00088 19.8 0.0 2.0 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 EAX96609.1 - 0.00034 20.6 7.9 0.7 10.3 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX96609.1 - 0.13 12.6 1.3 0.75 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX96609.1 - 0.17 12.8 0.3 2.7 9.0 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Spo12 PF05032.12 EAX96611.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Pox_A32 PF04665.12 EAX96612.1 - 2.6e-05 23.8 2.3 2.6e-05 23.8 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX96612.1 - 0.0023 18.0 0.2 0.0053 16.8 0.2 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX96612.1 - 0.017 14.7 0.3 0.034 13.7 0.3 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1722 PF08349.11 EAX96612.1 - 0.032 14.5 0.9 0.084 13.2 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Glyco_trans_1_3 PF13528.6 EAX96612.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ARA70 PF12489.8 EAX96613.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator SH3_9 PF14604.6 EAX96614.1 - 0.0014 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAX96614.1 - 0.018 14.6 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain CENP-F_leu_zip PF10473.9 EAX96614.1 - 0.029 14.4 1.5 0.029 14.4 1.5 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 EAX96614.1 - 0.48 11.1 1.8 5.9 7.6 0.4 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Peptidase_S8 PF00082.22 EAX96616.1 - 1.5e-20 73.6 0.0 1.8e-19 70.2 0.0 2.1 1 1 0 1 1 1 1 Subtilase family HflK_N PF12221.8 EAX96616.1 - 0.12 12.4 0.1 0.64 10.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial membrane protein N terminal EGF_2 PF07974.13 EAX96616.1 - 1.1 9.7 17.8 0.066 13.6 10.8 2.4 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EAX96616.1 - 1.2 9.9 6.9 4.3 8.1 6.9 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EAX96616.1 - 3.2 7.9 7.0 8.7 6.5 7.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain RICTOR_V PF14668.6 EAX96617.1 - 0.15 12.3 1.3 25 5.2 0.0 3.9 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 zf-rbx1 PF12678.7 EAX96618.1 - 4.2e-15 55.8 14.6 5e-15 55.5 14.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAX96618.1 - 2.7e-12 46.6 7.9 3.1e-12 46.4 7.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAX96618.1 - 1.3e-05 25.4 16.8 0.00021 21.5 16.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX96618.1 - 0.057 13.3 14.5 0.081 12.8 8.0 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EAX96618.1 - 0.13 12.3 1.2 0.13 12.3 1.2 2.5 1 1 1 2 2 2 0 Zinc-finger FANCL_C PF11793.8 EAX96618.1 - 0.17 12.0 15.1 8.6 6.6 15.1 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EAX96618.1 - 0.23 11.3 13.2 0.61 10.0 7.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EAX96618.1 - 0.66 10.0 17.6 0.94 9.5 10.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EAX96618.1 - 1 9.4 14.4 9.8 6.2 14.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain C1_2 PF03107.16 EAX96618.1 - 9.7 6.6 17.1 0.095 13.0 2.8 2.8 2 1 1 3 3 3 0 C1 domain F5_F8_type_C PF00754.25 EAX96619.1 - 1.9e-05 24.8 0.9 3.4e-05 23.9 0.9 1.3 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 EAX96619.1 - 0.023 14.8 0.1 0.047 13.8 0.1 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Ribosomal_L15e PF00827.17 EAX96620.1 - 7.6e-81 270.4 0.8 8.6e-81 270.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ank_2 PF12796.7 EAX96621.1 - 8.5e-70 231.4 4.0 1.7e-18 66.9 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96621.1 - 6.2e-34 115.9 0.1 2e-10 41.0 0.0 4.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96621.1 - 2.1e-31 107.6 2.1 9.3e-08 32.2 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX96621.1 - 7.6e-29 98.9 0.6 7.2e-05 23.1 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 EAX96621.1 - 7.9e-23 78.1 0.0 0.0027 18.0 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat ALMT PF11744.8 EAX96621.1 - 0.58 8.9 6.1 0.78 8.5 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DDE_Tnp_4 PF13359.6 EAX96622.1 - 9.5e-30 103.4 0.1 1.4e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EAX96622.1 - 9.2e-15 54.9 0.1 1.7e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EAX96622.1 - 0.0042 16.8 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Plant_tran PF04827.14 EAX96622.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Plant transposon protein c-SKI_SMAD_bind PF08782.10 EAX96622.1 - 0.03 14.5 0.9 11 6.4 0.2 3.2 3 0 0 3 3 3 0 c-SKI Smad4 binding domain PspB PF06667.12 EAX96622.1 - 0.061 13.4 0.0 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 Phage shock protein B SPATA3 PF15662.5 EAX96622.1 - 0.19 12.3 10.0 0.46 11.1 10.0 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF2486 PF10667.9 EAX96622.1 - 0.28 11.4 7.6 0.39 10.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) HTH_40 PF14493.6 EAX96623.1 - 0.039 14.4 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ank_2 PF12796.7 EAX96624.1 - 3.5e-102 335.2 9.4 6.7e-20 71.5 0.1 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96624.1 - 1.5e-62 207.2 0.2 1.4e-12 47.8 0.0 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX96624.1 - 1.2e-60 199.5 1.4 9.9e-07 28.9 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX96624.1 - 7.6e-57 188.6 0.0 2.5e-10 40.4 0.0 8.4 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96624.1 - 3.5e-47 152.9 0.1 0.00099 19.4 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat YfmQ PF10787.9 EAX96624.1 - 5.6e-05 23.0 2.6 5.2 6.8 0.0 5.6 3 1 3 6 6 6 1 Uncharacterised protein from bacillus cereus group Atg14 PF10186.9 EAX96624.1 - 0.0038 16.4 6.4 0.0054 15.9 6.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Lipase_chap PF03280.14 EAX96624.1 - 0.013 15.5 2.1 0.018 15.0 2.1 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Dynamitin PF04912.14 EAX96624.1 - 0.04 13.3 8.3 0.057 12.7 8.3 1.2 1 0 0 1 1 1 0 Dynamitin DUF1147 PF06615.11 EAX96624.1 - 0.047 13.8 1.4 11 6.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1147) CCDC84 PF14968.6 EAX96624.1 - 0.1 12.2 3.9 0.26 10.9 3.8 1.7 2 0 0 2 2 2 0 Coiled coil protein 84 DUF3450 PF11932.8 EAX96624.1 - 0.11 11.7 10.3 0.17 11.2 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EAX96624.1 - 0.15 12.6 13.7 0.29 11.7 13.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region USP8_interact PF08941.10 EAX96624.1 - 0.72 9.6 5.4 1.5 8.6 5.4 1.5 1 0 0 1 1 1 0 USP8 interacting TMPIT PF07851.13 EAX96624.1 - 1.7 7.8 9.3 2.5 7.3 9.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 EAX96624.1 - 1.9 7.8 12.3 3.5 6.9 12.3 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 EAX96624.1 - 9.5 5.5 7.5 15 4.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rcd1 PF04078.13 EAX96625.1 - 1.5e-92 309.5 1.0 1.9e-92 309.2 1.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Radial_spoke PF04712.12 EAX96626.1 - 7.3e-16 58.2 10.7 3.4e-09 36.2 6.2 2.7 3 1 0 3 3 3 2 Radial spokehead-like protein DUF4770 PF15994.5 EAX96626.1 - 0.16 12.2 1.1 0.24 11.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Pox_Ag35 PF03286.14 EAX96626.1 - 3.1 7.6 7.1 4.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CAF1 PF04857.20 EAX96627.1 - 4.7e-19 68.7 4.1 6.3e-10 38.7 0.1 2.9 2 1 0 2 2 2 2 CAF1 family ribonuclease Pkinase_Tyr PF07714.17 EAX96629.1 - 1.2e-55 188.6 0.0 1.8e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX96629.1 - 1.2e-54 185.4 0.0 2.8e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RICTOR_M PF14666.6 EAX96629.1 - 0.00086 19.0 0.6 0.0047 16.7 0.1 2.4 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain Kinase-like PF14531.6 EAX96629.1 - 0.00099 18.5 0.0 0.0029 17.0 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX96629.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX96629.1 - 0.069 11.9 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EAX96629.1 - 0.086 12.8 0.1 0.32 10.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4576 PF15144.6 EAX96629.1 - 0.095 12.6 0.0 0.37 10.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Clathrin-link PF09268.10 EAX96629.1 - 0.17 11.2 0.9 0.56 9.6 0.9 1.9 1 0 0 1 1 1 0 Clathrin, heavy-chain linker bacHORMA_2 PF18173.1 EAX96629.1 - 0.2 11.5 0.7 0.45 10.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial HORMA domain 2 RICTOR_V PF14668.6 EAX96629.1 - 0.29 11.4 1.7 0.9 9.8 0.2 2.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 NPV_P10 PF05531.12 EAX96629.1 - 6.6 7.3 9.9 36 4.9 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein GGDEF PF00990.21 EAX96632.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PcfK PF14058.6 EAX96632.1 - 0.086 13.1 9.1 0.12 12.6 9.1 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX96632.1 - 8 6.4 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX96633.1 - 4.4e-05 23.6 1.3 7.7e-05 22.8 1.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX96633.1 - 0.00052 19.8 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX96633.1 - 0.00068 19.9 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX96633.1 - 0.0015 18.4 0.1 0.0027 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX96633.1 - 0.0099 16.2 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX96633.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX96633.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 EAX96634.1 - 5.5e-139 463.3 0.0 2.1e-138 461.4 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX96634.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Pkinase PF00069.25 EAX96635.1 - 1.6e-22 80.1 0.1 2.1e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96635.1 - 3e-10 39.8 0.0 3.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX96635.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAX96635.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_10 PF14788.6 EAX96636.1 - 0.00071 19.4 0.1 0.00096 19.0 0.1 1.2 1 0 0 1 1 1 1 EF hand FLYWCH PF04500.16 EAX96641.1 - 0.034 14.3 3.6 0.054 13.6 3.6 1.3 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAR1 PF03101.15 EAX96641.1 - 0.07 13.8 1.0 0.16 12.7 1.0 1.5 1 1 0 1 1 1 0 FAR1 DNA-binding domain Myb_DNA-binding PF00249.31 EAX96642.1 - 2.2e-27 95.0 3.7 4.3e-13 49.2 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96642.1 - 9.2e-21 73.9 4.8 1e-12 48.1 0.7 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96642.1 - 0.0032 17.3 0.9 0.017 15.0 0.2 2.5 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX96642.1 - 0.0082 16.3 0.2 0.17 12.1 0.1 2.6 1 1 1 2 2 2 1 Rap1 Myb domain MADF_DNA_bdg PF10545.9 EAX96642.1 - 0.018 15.4 3.1 2.1 8.7 0.3 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 EAX96642.1 - 0.16 12.3 7.4 2.1 8.8 0.8 2.8 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Mannitol_dh PF01232.23 EAX96643.1 - 0.28 11.3 0.7 0.43 10.7 0.7 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Corona_S2 PF01601.16 EAX96644.1 - 2.1e-06 26.5 4.1 3.1e-06 26.0 4.1 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Shisa PF13908.6 EAX96644.1 - 1.1e-05 25.8 14.6 1.1e-05 25.8 14.6 3.5 2 2 2 4 4 4 1 Wnt and FGF inhibitory regulator DUF5125 PF17163.4 EAX96644.1 - 0.0033 17.6 0.2 0.024 14.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5125) Stevor PF17410.2 EAX96644.1 - 0.0095 15.5 1.3 0.022 14.3 1.3 1.6 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 EAX96644.1 - 0.013 16.4 0.2 0.013 16.4 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 EAX96644.1 - 1.8 8.7 4.4 4.6 7.4 4.4 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4834 PF16118.5 EAX96644.1 - 5.7 8.0 6.5 9.6 7.2 3.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Ank_2 PF12796.7 EAX96645.1 - 2.9e-140 457.2 1.9 8.7e-22 77.5 0.0 6.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96645.1 - 3.2e-81 266.7 0.0 2.2e-09 37.6 0.0 6.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX96645.1 - 3.3e-75 247.2 0.0 4.3e-10 39.6 0.0 9.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX96645.1 - 6e-68 222.5 0.0 1e-05 25.7 0.0 10.2 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 EAX96645.1 - 7.8e-50 161.1 0.0 0.0012 19.1 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat L_protein_N PF15518.6 EAX96645.1 - 4.9e-08 32.7 0.0 6.1 6.8 0.0 6.6 1 1 6 7 7 7 2 L protein N-terminus FBD PF08387.10 EAX96645.1 - 1.1e-06 28.5 4.0 33 4.4 0.0 6.7 6 2 0 6 6 6 0 FBD DBD_Tnp_Hermes PF10683.9 EAX96645.1 - 0.0097 15.6 0.0 63 3.4 0.0 5.5 8 0 0 8 8 8 0 Hermes transposase DNA-binding domain Baculo_p24 PF05073.12 EAX96645.1 - 0.061 13.1 5.9 0.48 10.2 5.9 2.6 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Mago-bind PF09282.10 EAX96645.1 - 1.1 9.2 9.0 2.1e+02 1.9 0.0 5.8 7 0 0 7 7 7 0 Mago binding Peptidase_C2 PF00648.21 EAX96646.1 - 5.5e-56 189.8 0.0 9.3e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF5427 PF10310.9 EAX96646.1 - 0.0093 15.0 9.9 0.014 14.4 9.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Calpain_III PF01067.22 EAX96646.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Calpain large subunit, domain III SpoIIIAH PF12685.7 EAX96646.1 - 2.7 7.8 8.6 5.7 6.7 8.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DCB PF16213.5 EAX96647.1 - 0.0011 18.7 1.4 0.0011 18.7 1.4 4.2 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 EAX96647.1 - 0.084 13.2 0.2 19 5.9 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat BPD_transp_1 PF00528.22 EAX96648.1 - 0.043 13.6 2.1 0.072 12.8 2.1 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component LepB_N PF18640.1 EAX96648.1 - 0.068 12.8 0.7 0.28 10.8 0.3 2.0 2 0 0 2 2 2 0 LepB N-terminal domain PNPase PF03726.14 EAX96648.1 - 0.099 13.1 1.8 0.24 11.9 1.4 1.7 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3744 PF12558.8 EAX96648.1 - 0.11 13.3 0.7 2.2 9.1 0.4 2.4 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter LapD_MoxY_N PF16448.5 EAX96649.1 - 0.0073 16.2 0.2 0.0093 15.8 0.2 1.3 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain Cut12 PF11500.8 EAX96650.1 - 0.042 13.8 1.6 0.061 13.3 1.6 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein ZYG-11_interact PF05884.12 EAX96650.1 - 0.088 12.2 0.3 0.094 12.1 0.3 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 Longin PF13774.6 EAX96651.1 - 1.3e-05 25.1 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain HAD_2 PF13419.6 EAX96652.1 - 8.4e-26 91.1 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX96652.1 - 1.6e-16 61.2 0.0 9.3e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX96652.1 - 4.3e-06 26.7 0.0 7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAX96652.1 - 0.17 12.0 0.1 2 8.6 0.0 2.4 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase CutA1 PF03091.15 EAX96652.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein LRR_5 PF13306.6 EAX96653.1 - 2.3e-27 95.5 15.9 1.1e-16 61.0 3.2 2.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96653.1 - 1e-06 28.4 0.8 8.8e-05 22.2 0.1 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 EAX96654.1 - 2.2e-29 102.0 17.0 1.1e-16 61.0 3.1 2.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96654.1 - 6.8e-07 29.0 0.2 8.8e-05 22.2 0.1 3.1 2 1 0 2 2 2 2 Leucine rich repeat Gly_rich PF12810.7 EAX96656.1 - 1.5e-38 133.1 36.8 1.8e-38 132.9 36.8 1.0 1 0 0 1 1 1 1 Glycine rich protein Pkinase PF00069.25 EAX96657.1 - 2.2e-50 171.5 0.0 3.4e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96657.1 - 1.8e-47 161.8 0.0 2.7e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 EAX96657.1 - 3.7e-31 106.9 51.0 0.00011 22.7 0.0 12.5 13 0 0 13 13 13 10 Sel1 repeat Kdo PF06293.14 EAX96657.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 EAX96657.1 - 0.47 10.7 0.0 0.47 10.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAX96657.1 - 2.6 8.0 7.5 40 4.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_A32 PF04665.12 EAX96658.1 - 5.4e-05 22.8 2.9 6.2e-05 22.6 1.9 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX96658.1 - 0.0058 16.7 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX96658.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX96658.1 - 0.085 13.1 1.5 0.21 11.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) IL17_R_N PF15037.6 EAX96660.1 - 0.13 11.1 2.1 1.6 7.6 0.5 2.1 1 1 1 2 2 2 0 Interleukin-17 receptor extracellular region EpuA PF11772.8 EAX96660.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF5348 PF17295.2 EAX96660.1 - 0.79 9.7 3.7 26 4.8 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5348) DUF4795 PF16043.5 EAX96660.1 - 1.3 8.6 13.3 1.8 8.1 0.5 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4795) DUF4106 PF13388.6 EAX96661.1 - 2.1e-225 748.7 20.0 2.1e-225 748.7 20.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4106) Alph_Pro_TM PF09608.10 EAX96661.1 - 0.043 13.6 0.2 0.085 12.7 0.2 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Pox_D5 PF03288.16 EAX96663.1 - 2.1e-05 24.9 2.3 0.00011 22.6 2.3 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX96663.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4108 PF13390.6 EAX96664.1 - 1e-61 207.0 7.1 1.2e-61 206.9 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) NMT PF01233.19 EAX96665.1 - 2.5 7.9 6.0 0.19 11.6 0.8 1.7 2 1 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Pox_A32 PF04665.12 EAX96666.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX96666.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX96666.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX96666.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX96666.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX96666.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX96666.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX96666.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX96666.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX96666.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX96666.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX96666.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX96667.1 - 4.1e-43 145.8 0.6 9.1e-43 144.7 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX96667.1 - 0.018 15.2 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX96667.1 - 0.3 9.6 0.2 0.43 9.1 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAX96668.1 - 3.1e-157 521.3 13.4 3.9e-157 520.9 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96668.1 - 0.081 13.4 2.4 0.11 12.9 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96668.1 - 0.54 10.8 6.8 2.5 8.6 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cache_3-Cache_2 PF17201.4 EAX96670.1 - 0.031 13.6 0.4 0.039 13.2 0.4 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain TMP PF05017.14 EAX96671.1 - 0.019 15.4 2.6 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96672.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX96673.1 - 4e-48 161.9 19.6 2.4e-15 56.9 0.3 5.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96673.1 - 2.4e-42 141.6 11.9 3e-06 27.4 1.0 9.8 8 2 2 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX96673.1 - 1.5e-39 133.9 10.2 2.4e-09 37.5 0.0 8.3 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96673.1 - 3.4e-34 113.0 14.0 0.00028 21.1 0.1 11.2 11 1 1 12 12 12 7 Ankyrin repeat DUF3447 PF11929.8 EAX96673.1 - 1.3e-33 114.8 18.2 5.5e-32 109.6 3.3 5.1 3 1 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX96673.1 - 2.2e-22 78.8 9.6 6.1e-06 26.4 0.1 9.1 4 4 6 10 10 10 6 Ankyrin repeats (many copies) ATR13 PF16829.5 EAX96673.1 - 0.12 12.8 1.0 0.3 11.5 0.3 2.1 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Ank_2 PF12796.7 EAX96674.1 - 5.4e-37 126.2 19.7 2.3e-14 53.7 0.9 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96674.1 - 1.2e-30 105.5 6.8 1e-12 48.3 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX96674.1 - 2.1e-27 94.3 7.3 1.3e-08 34.9 0.0 4.9 5 1 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EAX96674.1 - 4.5e-23 81.0 5.7 4.5e-23 81.0 5.7 2.7 2 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX96674.1 - 1.5e-22 77.3 5.5 8e-07 28.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX96674.1 - 8.3e-18 64.2 6.4 7.2e-09 35.7 0.1 4.2 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Peptidase_M57 PF12388.8 EAX96674.1 - 0.13 11.9 2.4 0.24 11.0 0.5 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Filament PF00038.21 EAX96678.1 - 0.0032 17.1 4.2 0.0042 16.7 4.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF2207 PF09972.9 EAX96678.1 - 0.0037 16.1 2.3 0.0048 15.7 2.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Pex24p PF06398.11 EAX96678.1 - 0.043 12.8 13.7 0.31 10.0 13.7 1.9 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin ColG_sub PF18496.1 EAX96678.1 - 0.063 13.4 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain T3SSipB PF16535.5 EAX96678.1 - 0.068 13.7 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB NEMO PF11577.8 EAX96678.1 - 0.092 12.8 3.6 0.52 10.4 0.5 2.7 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO DUF3944 PF13099.6 EAX96678.1 - 0.099 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) DUF1664 PF07889.12 EAX96678.1 - 1.4 9.0 4.8 1.9 8.5 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LRR_6 PF13516.6 EAX96679.1 - 0.00043 20.1 8.2 0.086 12.9 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EAX96679.1 - 0.041 14.3 11.7 0.32 11.5 1.0 5.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EAX96680.1 - 1.4e-10 41.6 0.0 2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96680.1 - 2.8e-09 37.3 0.0 0.00014 22.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX96680.1 - 1.6e-07 31.5 0.0 0.0016 18.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX96680.1 - 9.6e-06 25.6 0.1 1.1 10.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAX96680.1 - 0.0072 16.3 1.4 0.0072 16.3 1.4 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3447 PF11929.8 EAX96681.1 - 2.2e-32 110.8 2.8 2.2e-32 110.8 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX96681.1 - 0.00011 22.7 0.1 0.00027 21.4 0.1 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ribosomal_S7 PF00177.21 EAX96682.1 - 0.13 11.9 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e MIG-14_Wnt-bd PF06664.12 EAX96684.1 - 0.00064 19.0 0.3 0.00094 18.5 0.3 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion NAD_binding_5 PF07994.12 EAX96684.1 - 0.024 14.1 4.1 0.034 13.5 4.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF3377 PF11857.8 EAX96684.1 - 0.38 10.7 3.0 0.77 9.7 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PSP PF04046.16 EAX96685.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96686.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF2939 PF11159.8 EAX96689.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX96689.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX96690.1 - 0.0073 16.3 0.2 0.0098 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Guanylate_cyc PF00211.20 EAX96693.1 - 1.7e-41 141.9 0.0 2.9e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX96693.1 - 3.9e-11 43.1 0.5 1.9e-10 40.9 0.2 2.3 2 0 0 2 2 2 1 PAS domain HNOBA PF07701.14 EAX96693.1 - 0.012 15.0 1.0 0.02 14.4 0.1 1.8 2 0 0 2 2 2 0 Heme NO binding associated Mad3_BUB1_I_2 PF17014.5 EAX96693.1 - 0.015 15.4 0.2 0.3 11.2 0.1 2.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein PAS_3 PF08447.12 EAX96693.1 - 0.028 14.7 0.0 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 EAX96693.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold LRR19-TM PF15176.6 EAX96697.1 - 0.012 15.6 1.7 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain UCH PF00443.29 EAX96697.1 - 0.023 14.2 2.9 0.089 12.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Peptidase_M29 PF02073.15 EAX96697.1 - 0.091 11.5 1.0 0.4 9.4 0.2 2.1 2 1 0 2 2 2 0 Thermophilic metalloprotease (M29) Intein_splicing PF14890.6 EAX96697.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.6 1 1 0 1 1 1 0 Intein splicing domain DUF5069 PF16798.5 EAX96697.1 - 0.15 12.3 0.9 0.31 11.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) MULE PF10551.9 EAX96698.1 - 4.1e-05 23.9 0.1 8.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAX96698.1 - 0.036 14.5 0.8 0.89 10.0 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAX96698.1 - 0.12 12.6 3.6 0.23 11.6 3.6 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain TraS PF10624.9 EAX96699.1 - 7.3 6.5 14.1 1.9 8.4 8.8 2.2 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS DUF3839 PF12943.7 EAX96701.1 - 2e-75 253.4 7.1 2.5e-75 253.1 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAX96702.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX96704.1 - 8e-72 240.7 3.6 1e-71 240.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX96704.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF1682 PF07946.14 EAX96706.1 - 0.0013 18.0 7.5 0.0013 18.0 7.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) DUF769 PF05590.11 EAX96706.1 - 0.081 12.4 0.1 0.13 11.7 0.0 1.4 2 0 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) Syntaxin-6_N PF09177.11 EAX96707.1 - 2 9.1 5.7 1.1 9.9 0.1 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DDE_Tnp_1_assoc PF13808.6 EAX96708.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-associated TM1586_NiRdase PF14512.6 EAX96710.1 - 9.8e-23 80.9 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 EAX96710.1 - 4.9e-05 23.5 0.0 0.0017 18.4 0.0 2.8 3 0 0 3 3 3 1 Nitroreductase family Aldo_ket_red PF00248.21 EAX96711.1 - 9e-45 153.1 0.0 2.1e-44 151.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Xol-1_GHMP-like PF09109.10 EAX96711.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like PSP PF04046.16 EAX96712.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96713.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX96717.1 - 1.4e-05 25.0 0.6 1.4e-05 25.0 0.6 2.8 3 0 0 3 3 3 2 Phage tail repeat like Phage_fiber PF03335.13 EAX96717.1 - 3 8.3 9.4 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Phage tail fibre repeat DUF1493 PF07377.12 EAX96718.1 - 0.08 13.4 0.6 0.17 12.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX96719.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96720.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX96721.1 - 7.3e-48 163.2 0.0 1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96721.1 - 1.1e-18 67.4 0.0 4.3e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX96721.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5097 PF17020.5 EAX96721.1 - 0.027 14.8 0.4 0.11 12.8 0.4 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5097) Choline_kinase PF01633.20 EAX96721.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EAX96721.1 - 0.045 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Histone PF00125.24 EAX96722.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX96722.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX96722.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAX96723.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX96723.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX96723.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX96723.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Ank_2 PF12796.7 EAX96724.1 - 1.3e-22 80.2 5.7 7.3e-13 48.9 2.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96724.1 - 1.6e-19 70.0 1.1 3.3e-09 37.1 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96724.1 - 2e-19 67.6 5.6 3.3e-05 23.9 0.2 6.0 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX96724.1 - 6e-15 55.1 1.8 1.5e-06 28.3 0.7 4.4 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX96724.1 - 1.9e-11 43.9 2.2 0.0025 18.2 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 EAX96724.1 - 0.41 10.6 6.0 1.6 8.7 1.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) WD40_like PF17005.5 EAX96725.1 - 0.02 14.2 2.4 0.18 11.1 0.7 2.2 1 1 1 2 2 2 0 WD40-like domain V_ATPase_I PF01496.19 EAX96726.1 - 5.5e-197 656.4 22.8 2.4e-150 502.1 5.0 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF489 PF04356.12 EAX96726.1 - 0.19 11.7 1.5 0.37 10.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Takusan PF04822.13 EAX96726.1 - 5.7 6.9 9.4 33 4.4 1.8 3.2 3 0 0 3 3 3 0 Takusan T5orf172 PF10544.9 EAX96727.1 - 4.1e-07 30.5 0.1 1.1e-06 29.2 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX96727.1 - 0.11 12.0 0.4 0.59 9.6 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain PTR PF12789.7 EAX96728.1 - 8.4e-48 160.3 32.8 1.3e-32 111.7 18.3 5.7 4 3 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX96728.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) AviRa PF11599.8 EAX96728.1 - 0.47 9.9 4.5 0.54 9.7 1.2 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PH_TFIIH PF08567.11 EAX96728.1 - 0.81 10.1 7.4 12 6.3 0.2 4.0 1 1 3 4 4 4 0 TFIIH p62 subunit, N-terminal domain TMP PF05017.14 EAX96730.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96731.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_6 PF13516.6 EAX96732.1 - 1.6e-25 86.9 26.4 0.045 13.8 0.0 13.1 14 0 0 14 14 14 8 Leucine Rich repeat LRR_4 PF12799.7 EAX96732.1 - 0.00044 20.6 25.4 0.24 11.9 3.1 7.6 4 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX96732.1 - 0.0088 15.8 15.9 2 8.2 4.0 6.6 5 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 EAX96732.1 - 0.034 14.7 12.2 6 7.8 0.1 6.9 8 1 1 9 9 9 0 Leucine Rich Repeat Spc7 PF08317.11 EAX96732.1 - 1.2 8.0 49.4 0.19 10.6 21.2 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Noelin-1 PF12308.8 EAX96732.1 - 3.2 7.8 17.5 0.97 9.4 2.4 3.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein HAUS-augmin3 PF14932.6 EAX96732.1 - 3.8 7.0 39.6 0.25 10.9 26.5 2.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Calreticulin PF00262.18 EAX96733.1 - 2.1e-116 388.8 2.5 2.5e-116 388.5 2.5 1.1 1 0 0 1 1 1 1 Calreticulin family Hyccin PF09790.9 EAX96735.1 - 0.041 13.0 0.1 0.14 11.2 0.1 1.9 1 0 0 1 1 1 0 Hyccin RTP1_C1 PF10363.9 EAX96735.1 - 8.6 6.6 6.7 92 3.3 0.1 5.0 5 2 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 AhpC-TSA PF00578.21 EAX96736.1 - 4.9e-40 136.3 0.0 7.2e-40 135.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAX96736.1 - 9.9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAX96736.1 - 2.1e-09 37.0 0.1 3.6e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin UTP25 PF06862.12 EAX96737.1 - 4.6e-126 421.4 1.4 7.1e-126 420.7 1.4 1.3 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Colicin_Pyocin PF01320.18 EAX96737.1 - 0.042 14.0 1.3 2.9 8.0 0.0 3.2 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein RasGEF PF00617.19 EAX96738.1 - 5.2e-12 46.3 0.0 1.3e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAX96738.1 - 0.0023 18.1 1.6 0.0023 18.1 1.6 2.2 3 0 0 3 3 3 1 RasGEF N-terminal motif LisH_TPL PF17814.1 EAX96738.1 - 0.27 10.9 1.1 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 LisH-like dimerisation domain DNA_pol_B_2 PF03175.13 EAX96739.1 - 5.1e-24 85.0 6.7 3e-23 82.4 6.7 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX96740.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX96741.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX96741.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX96741.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX96742.1 - 0.012 15.6 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DDR PF08841.10 EAX96744.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Helicase_C_2 PF13307.6 EAX96747.1 - 8.6e-50 169.2 0.0 3.3e-49 167.3 0.0 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAX96747.1 - 5.4e-37 127.1 5.0 5.4e-37 127.1 5.0 2.4 3 0 0 3 3 2 1 DEAD_2 zf-C3HC4_3 PF13920.6 EAX96747.1 - 1.4e-05 24.8 12.0 6e-05 22.8 12.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EAX96747.1 - 0.00025 20.8 0.1 0.028 14.2 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX96747.1 - 0.0048 16.9 0.1 0.0048 16.9 0.1 3.4 2 2 0 2 2 1 1 Type III restriction enzyme, res subunit zf-RING_4 PF14570.6 EAX96747.1 - 0.28 11.0 10.2 0.97 9.3 10.2 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EAX96747.1 - 2.2 8.3 20.5 0.075 13.0 12.9 2.6 3 0 0 3 3 3 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EAX96747.1 - 2.4 7.7 7.6 0.94 9.0 1.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 EAX96747.1 - 2.5 8.2 8.5 2 8.5 3.8 3.1 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 EAX96747.1 - 2.6 8.4 16.7 0.27 11.6 10.1 2.9 3 0 0 3 3 3 0 Ring finger domain zf-RING_10 PF16685.5 EAX96747.1 - 4.4 7.5 16.8 0.47 10.6 10.5 2.7 2 1 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EAX96747.1 - 5.3 7.0 21.7 0.035 14.0 10.3 2.9 4 0 0 4 4 3 0 Prokaryotic RING finger family 4 Clat_adaptor_s PF01217.20 EAX96748.1 - 1.6e-31 109.1 0.2 2.1e-31 108.8 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 EAX96748.1 - 0.074 13.0 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Ank PF00023.30 EAX96749.1 - 2.1e-112 363.1 42.9 1.3e-08 34.9 0.1 15.4 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.6 EAX96749.1 - 1.4e-102 334.8 55.3 3.5e-13 49.8 0.1 15.5 3 1 14 17 17 17 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96749.1 - 2.6e-102 335.6 74.7 5.7e-17 62.1 5.2 10.0 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96749.1 - 6e-83 262.8 42.2 3.8e-06 26.8 0.0 16.9 18 0 0 18 18 17 14 Ankyrin repeat Ank_5 PF13857.6 EAX96749.1 - 3.8e-63 208.7 31.4 2.1e-09 37.4 0.1 11.0 4 2 5 11 11 11 10 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96749.1 - 1.4e-34 117.8 7.9 1.4e-34 117.8 7.9 6.3 5 2 1 7 7 7 1 Domain of unknown function (DUF3447) Arg_repressor PF01316.21 EAX96749.1 - 0.0024 17.6 3.1 31 4.4 0.0 7.6 10 0 0 10 10 10 0 Arginine repressor, DNA binding domain DUF3895 PF13034.6 EAX96749.1 - 0.0041 17.1 2.4 3.1 7.9 0.1 4.9 3 2 0 3 3 3 1 Protein of unknown function (DUF3895) Adeno_E4_34 PF04528.13 EAX96749.1 - 0.01 15.7 4.3 8.8 6.2 0.1 4.9 4 1 0 5 5 5 0 Adenovirus early E4 34 kDa protein conserved region Lipoprotein_3 PF00938.17 EAX96749.1 - 0.13 12.5 4.5 35 4.7 0.0 4.6 4 1 1 5 5 5 0 Lipoprotein DUF3677 PF12432.8 EAX96749.1 - 0.13 12.6 1.0 45 4.5 0.0 5.4 8 0 0 8 8 8 0 Protein of unknown function (DUF3677) Glyoxalase_4 PF13669.6 EAX96749.1 - 0.17 12.1 1.8 11 6.3 0.0 3.6 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PrmC_N PF17827.1 EAX96749.1 - 0.21 12.2 3.6 73 4.1 0.2 5.4 4 2 2 6 6 6 0 PrmC N-terminal domain DUF4147 PF13660.6 EAX96749.1 - 2.6 7.5 10.6 45 3.5 0.0 6.7 9 2 2 11 11 11 0 Domain of unknown function (DUF4147) Importin_rep_5 PF18816.1 EAX96749.1 - 4.2 7.7 10.1 38 4.7 0.3 4.3 5 0 0 5 5 4 0 Importin repeat Pkinase PF00069.25 EAX96750.1 - 1.4e-46 159.0 0.3 3.6e-46 157.7 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96750.1 - 3.7e-32 111.6 0.0 9e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX96750.1 - 0.0011 17.8 0.2 0.0026 16.6 0.2 1.7 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAX96750.1 - 0.0036 17.0 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EAX96750.1 - 0.045 13.1 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EAX96750.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family BLOC1_2 PF10046.9 EAX96751.1 - 6.2e-06 26.4 0.7 0.015 15.6 0.0 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 EAX96751.1 - 4.4e-05 23.8 0.1 5.8e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Snapin/Pallidin CLZ PF16526.5 EAX96751.1 - 0.00051 20.4 0.3 0.58 10.6 0.1 2.1 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 EAX96751.1 - 0.0056 16.9 0.1 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 ABC transporter C-terminal domain NTR2 PF15458.6 EAX96751.1 - 0.0059 16.2 1.7 0.0066 16.0 1.7 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 FapA PF03961.13 EAX96751.1 - 0.0091 14.6 1.0 0.01 14.5 1.0 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 EAX96751.1 - 0.011 16.1 1.9 0.042 14.2 0.4 2.0 1 1 1 2 2 2 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 EAX96751.1 - 0.013 16.0 0.1 0.043 14.4 0.0 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 EAX96751.1 - 0.015 15.5 0.8 0.057 13.7 0.7 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.12 EAX96751.1 - 0.016 13.4 0.9 0.028 12.6 0.9 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA WASH-7_N PF14745.6 EAX96751.1 - 0.017 13.7 0.1 0.019 13.5 0.1 1.0 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal DivIC PF04977.15 EAX96751.1 - 0.021 14.6 3.5 0.024 14.4 0.1 2.3 2 1 1 3 3 3 0 Septum formation initiator Baculo_PEP_C PF04513.12 EAX96751.1 - 0.022 14.8 2.8 0.22 11.6 1.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EAX96751.1 - 0.028 14.5 1.6 1.1 9.4 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EAX96751.1 - 0.037 14.0 0.2 0.071 13.1 0.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps5 PF09325.10 EAX96751.1 - 0.042 13.4 0.2 0.048 13.2 0.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF2730 PF10805.8 EAX96751.1 - 0.053 13.6 0.1 0.078 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) KxDL PF10241.9 EAX96751.1 - 0.071 13.4 0.4 0.48 10.7 0.4 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein CUTL PF16557.5 EAX96751.1 - 0.075 13.2 0.9 8 6.7 0.4 2.1 1 1 1 2 2 2 0 CUT1-like DNA-binding domain of SATB CheX PF13690.6 EAX96751.1 - 0.082 13.1 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX DUF2203 PF09969.9 EAX96751.1 - 0.12 13.1 0.1 0.21 12.3 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prefoldin_2 PF01920.20 EAX96751.1 - 0.12 12.3 1.4 1.9 8.5 0.0 2.5 2 1 0 2 2 2 0 Prefoldin subunit Trimer_CC PF08954.11 EAX96751.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif Fib_alpha PF08702.10 EAX96751.1 - 0.15 12.3 1.5 0.27 11.4 1.5 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4988 PF16378.5 EAX96751.1 - 0.39 10.4 2.4 0.67 9.6 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function SWIRM PF04433.17 EAX96752.1 - 6e-09 36.1 0.1 2e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EAX96752.1 - 1.9e-05 24.7 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain YlbD_coat PF14071.6 EAX96752.1 - 0.021 15.1 0.3 0.047 13.9 0.3 1.6 1 0 0 1 1 1 0 Putative coat protein TCR PF03638.15 EAX96753.1 - 8.4e-06 26.0 27.0 1.3e-05 25.4 27.0 1.3 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain MCD_N PF17408.2 EAX96753.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.7 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain WD40 PF00400.32 EAX96754.1 - 9.2e-15 54.8 6.9 5.8e-07 30.1 0.1 4.8 3 1 1 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX96754.1 - 3.1e-06 27.4 0.1 0.45 10.9 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 EAX96755.1 - 9.8e-05 22.4 2.8 0.0002 21.4 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EAX96755.1 - 0.042 14.1 1.5 0.081 13.2 0.8 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nsp1_C PF05064.13 EAX96755.1 - 0.06 13.2 0.6 0.29 10.9 0.6 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region WASH_WAHD PF11945.8 EAX96755.1 - 0.13 11.7 0.6 0.29 10.6 0.6 1.5 1 0 0 1 1 1 0 WAHD domain of WASH complex TMPIT PF07851.13 EAX96755.1 - 0.14 11.4 0.3 0.21 10.8 0.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFT57 PF10498.9 EAX96755.1 - 0.14 11.1 1.9 0.26 10.2 1.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PMC2NT PF08066.12 EAX96755.1 - 0.23 12.1 1.2 0.51 11.0 1.2 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF948 PF06103.11 EAX96755.1 - 0.34 11.2 2.2 1.4 9.2 0.3 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EAX96755.1 - 0.9 9.6 5.0 1.7 8.6 5.0 1.4 1 0 0 1 1 1 0 Laminin Domain II ApoLp-III PF07464.11 EAX96755.1 - 6.4 6.9 7.7 11 6.1 0.6 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4600 PF15372.6 EAX96756.1 - 0.019 15.4 11.0 0.019 15.4 11.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DASH_Dad2 PF08654.10 EAX96756.1 - 0.03 14.7 0.5 0.03 14.7 0.5 2.4 1 1 0 2 2 2 0 DASH complex subunit Dad2 DUF4407 PF14362.6 EAX96756.1 - 0.051 12.9 11.4 0.062 12.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EAX96756.1 - 0.053 13.0 13.3 0.059 12.8 13.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 EAX96756.1 - 0.21 12.0 21.1 0.059 13.7 8.5 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ORC3_N PF07034.11 EAX96756.1 - 0.23 10.5 4.4 0.29 10.2 4.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus SLATT_3 PF18184.1 EAX96756.1 - 0.61 10.2 2.5 0.85 9.8 0.9 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 NPV_P10 PF05531.12 EAX96756.1 - 0.62 10.6 5.2 0.4 11.2 2.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein 60KD_IMP PF02096.20 EAX96756.1 - 0.91 9.4 7.1 5.3 6.9 1.8 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein WXG100 PF06013.12 EAX96756.1 - 1.3 9.3 7.9 26 5.2 0.9 3.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Mod_r PF07200.13 EAX96756.1 - 1.3 9.1 19.7 2.4 8.2 13.7 2.5 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Cauli_AT PF03233.13 EAX96756.1 - 1.8 8.5 12.9 10 6.0 8.2 2.7 1 1 0 2 2 2 0 Aphid transmission protein OmpH PF03938.14 EAX96756.1 - 2.1 8.7 22.6 11 6.3 22.6 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 EAX96756.1 - 2.3 7.8 9.2 2.8 7.5 6.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 EAX96756.1 - 2.6 7.0 15.7 3.4 6.7 15.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 EAX96756.1 - 4.2 7.4 17.6 0.59 10.1 8.3 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ING PF12998.7 EAX96756.1 - 8.4 7.1 16.4 2.7 8.7 10.2 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 EAX96756.1 - 8.8 6.4 11.6 1.2e+02 2.7 11.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 EAX96756.1 - 9.9 6.7 14.9 1.9e+02 2.6 15.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2730 PF10805.8 EAX96757.1 - 0.03 14.4 2.2 0.03 14.4 2.2 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) DUF2389 PF09493.10 EAX96757.1 - 0.52 11.0 1.9 24 5.7 0.1 3.5 3 0 0 3 3 3 0 Tryptophan-rich protein (DUF2389) Mod_r PF07200.13 EAX96757.1 - 0.99 9.5 55.4 2.4 8.2 8.3 5.2 2 2 3 5 5 5 0 Modifier of rudimentary (Mod(r)) protein RuBisCO_small PF00101.20 EAX96757.1 - 1.8 8.6 7.7 1 9.4 1.2 3.4 3 1 0 3 3 3 0 Ribulose bisphosphate carboxylase, small chain AAA_5 PF07728.14 EAX96757.1 - 2.4 8.1 5.6 1 9.3 1.5 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) CDC50 PF03381.15 EAX96760.1 - 9.1e-61 205.8 0.6 1.1e-60 205.5 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4064 PF13273.6 EAX96760.1 - 0.0052 17.0 1.8 3.1 8.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) DUF5305 PF17231.2 EAX96760.1 - 0.0065 15.9 0.2 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Otopetrin PF03189.13 EAX96760.1 - 0.018 13.9 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Otopetrin SAYSvFN PF10260.9 EAX96760.1 - 0.099 12.6 5.9 0.47 10.4 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) WD40 PF00400.32 EAX96761.1 - 1.5e-34 117.4 11.3 2.6e-07 31.2 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat Utp13 PF08625.11 EAX96761.1 - 3e-28 98.5 0.3 1.1e-27 96.7 0.1 2.0 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain WD40_like PF17005.5 EAX96761.1 - 9.8e-12 44.8 0.0 0.00062 19.2 0.0 4.3 4 0 0 4 4 4 4 WD40-like domain ANAPC4_WD40 PF12894.7 EAX96761.1 - 3.6e-09 36.8 1.1 0.11 12.8 0.0 6.0 2 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAX96761.1 - 9.5e-06 24.5 1.7 0.053 12.2 0.0 4.5 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAX96761.1 - 0.0021 17.1 5.9 0.44 9.4 0.5 4.8 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5074 PF16819.5 EAX96761.1 - 0.036 14.1 0.7 0.24 11.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5074) Clathrin_H_link PF13838.6 EAX96761.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Clathrin-H-link Vps16_N PF04841.13 EAX96762.1 - 2.9e-16 59.3 0.0 6.6e-16 58.1 0.0 1.5 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAX96762.1 - 2.7e-06 26.6 0.1 6.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Vps16, C-terminal region Plasmodium_Vir PF05795.11 EAX96762.1 - 1.6 8.1 20.9 4.3 6.7 20.4 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF2201_N PF13203.6 EAX96762.1 - 8 6.0 8.4 16 4.9 7.4 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Ank_2 PF12796.7 EAX96764.1 - 7.3e-65 215.6 27.1 3.3e-15 56.4 0.4 7.2 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96764.1 - 6.2e-59 195.7 19.6 9.2e-12 45.2 0.1 11.2 6 3 5 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX96764.1 - 5e-53 175.4 15.8 2e-08 34.3 0.0 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 EAX96764.1 - 3.2e-51 165.3 21.3 9.7e-07 28.6 0.0 13.6 15 0 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 EAX96764.1 - 1.1e-45 153.0 14.7 9.2e-09 35.4 0.1 10.3 5 3 8 13 13 13 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96764.1 - 2.9e-20 72.0 7.3 2.9e-20 72.0 7.3 5.2 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) TauE PF01925.19 EAX96765.1 - 1.1e-25 90.7 32.4 2.7e-23 82.8 32.4 2.2 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE EcoRI_methylase PF13651.6 EAX96765.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI UPF0506 PF11703.8 EAX96765.1 - 2.4 8.6 9.1 3.8 8.0 9.1 1.2 1 0 0 1 1 1 0 UPF0506 PetG PF02529.15 EAX96765.1 - 2.6 8.0 7.0 38 4.2 0.8 3.7 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit 5 DUF1240 PF06836.12 EAX96765.1 - 5.5 7.6 7.8 1.8 9.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) TetR_C_19 PF17924.1 EAX96766.1 - 0.031 14.9 5.1 0.047 14.3 5.1 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MULE PF10551.9 EAX96767.1 - 0.034 14.6 1.9 0.13 12.6 0.1 2.8 3 0 0 3 3 3 0 MULE transposase domain DUF2960 PF11173.8 EAX96767.1 - 0.083 13.3 0.2 0.22 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Gly-zipper_Omp PF13488.6 EAX96768.1 - 0.035 14.1 10.4 0.035 14.1 10.4 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX96768.1 - 0.54 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF3839 PF12943.7 EAX96769.1 - 8.4e-155 513.3 12.5 1.1e-154 512.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX96769.1 - 0.14 12.6 5.2 1.7 9.2 0.1 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX96769.1 - 0.92 9.9 5.4 16 5.8 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal DUF2408 PF10303.9 EAX96769.1 - 1.9 9.0 5.8 0.41 11.2 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) BHD_1 PF10403.9 EAX96770.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 SAC3_GANP PF03399.16 EAX96771.1 - 7.2e-52 176.6 0.2 1e-51 176.1 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family EIIBC-GUT_N PF03612.14 EAX96771.1 - 0.39 10.4 2.4 0.68 9.6 2.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Tim54 PF11711.8 EAX96771.1 - 5.9 5.6 8.7 8.6 5.0 8.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RACo_C_ter PF14574.6 EAX96772.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain GAPT PF11770.8 EAX96773.1 - 0.098 12.5 2.5 3.9 7.3 0.6 2.5 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF3060 PF11259.8 EAX96773.1 - 0.23 11.2 7.4 0.047 13.4 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Shisa PF13908.6 EAX96773.1 - 0.36 11.0 4.1 0.62 10.3 4.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 EAX96773.1 - 1.6 8.6 4.4 2.9 7.8 4.4 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Ank_4 PF13637.6 EAX96774.1 - 1.3e-47 159.5 14.6 1.4e-12 47.8 0.2 9.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX96774.1 - 6.2e-45 149.7 10.6 1.9e-06 28.0 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.7 EAX96774.1 - 2.6e-44 149.7 22.3 3e-16 59.8 5.3 5.0 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX96774.1 - 3.4e-38 129.4 7.5 3.4e-38 129.4 7.5 3.5 2 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX96774.1 - 3.4e-35 116.1 13.9 1.1e-05 25.4 0.0 9.5 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EAX96774.1 - 8.8e-31 105.6 9.0 5.9e-07 29.6 0.1 6.3 6 1 1 7 7 7 5 Ankyrin repeats (many copies) LRR_4 PF12799.7 EAX96775.1 - 4.1e-15 55.6 16.9 1.1e-06 28.8 4.3 3.9 2 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX96775.1 - 9e-14 51.3 4.6 3e-09 36.6 0.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAX96775.1 - 5.7e-09 35.6 12.3 3.5e-05 23.5 1.6 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EAX96775.1 - 0.092 13.4 9.6 25 5.9 0.1 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EAX96775.1 - 0.53 10.5 5.9 13 6.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat RRM_1 PF00076.22 EAX96776.1 - 3.6e-06 26.7 0.0 8.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EAX96776.1 - 6e-05 23.7 1.6 0.075 13.7 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 EAX96776.1 - 7.4e-05 22.5 2.7 0.0012 18.6 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAX96776.1 - 9.1e-05 22.4 4.7 0.066 13.3 0.4 2.4 2 0 0 2 2 2 2 Zinc finger domain Haemadin PF09065.10 EAX96776.1 - 0.42 10.4 2.8 20 5.1 2.0 2.5 2 0 0 2 2 2 0 Haemadin Peptidase_M8 PF01457.16 EAX96777.1 - 9.8e-08 31.1 0.0 1.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin DUF2755 PF10954.8 EAX96777.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) PAS PF00989.25 EAX96779.1 - 0.098 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Sigma70_r3 PF04539.16 EAX96779.1 - 0.1 12.7 0.1 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 PAS_9 PF13426.7 EAX96779.1 - 0.14 12.4 0.4 0.68 10.2 0.4 2.2 1 1 0 1 1 1 0 PAS domain Pkinase PF00069.25 EAX96781.1 - 4.1e-19 69.0 0.7 5.2e-19 68.6 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96781.1 - 8.9e-15 54.7 0.3 1.1e-14 54.4 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96781.1 - 0.00086 18.7 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3078 PF11276.8 EAX96783.1 - 0.031 14.7 2.1 0.15 12.5 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3078) PH PF00169.29 EAX96785.1 - 2.6e-14 53.6 2.5 3.9e-14 53.0 0.1 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EAX96785.1 - 5.7e-05 23.5 2.1 5.7e-05 23.5 2.1 3.8 2 1 0 2 2 2 1 Pleckstrin homology domain Vps35 PF03635.17 EAX96786.1 - 3e-174 581.5 6.4 3.5e-174 581.3 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ras PF00071.22 EAX96787.1 - 1.2e-52 177.8 0.2 1.4e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96787.1 - 1.9e-32 112.0 0.0 2.8e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96787.1 - 3.3e-16 59.2 0.1 3.8e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX96787.1 - 1.6e-06 28.1 0.6 0.034 14.0 0.4 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAX96787.1 - 1.1e-05 25.5 0.1 3.1e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX96787.1 - 1.2e-05 25.6 0.2 0.00025 21.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 EAX96787.1 - 5.4e-05 22.7 0.0 6.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EAX96787.1 - 0.00022 21.1 0.3 0.036 13.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAX96787.1 - 0.00036 20.0 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAX96787.1 - 0.00094 18.7 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 EAX96787.1 - 0.002 17.7 0.2 0.024 14.2 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAX96787.1 - 0.0021 17.7 0.1 0.038 13.5 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EAX96787.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX96787.1 - 0.0059 17.0 1.4 0.02 15.3 1.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX96787.1 - 0.0093 15.9 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Septin PF00735.18 EAX96787.1 - 0.0095 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Septin MobB PF03205.14 EAX96787.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EAX96787.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX96787.1 - 0.048 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX96787.1 - 0.049 14.2 0.0 0.062 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_32 PF13654.6 EAX96787.1 - 0.052 12.3 0.0 0.89 8.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EAX96787.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAX96787.1 - 0.1 12.6 0.1 0.38 10.7 0.1 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) PRK PF00485.18 EAX96787.1 - 0.1 12.3 0.2 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EAX96787.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain DDR PF08841.10 EAX96788.1 - 0.041 12.9 0.1 0.042 12.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX96788.1 - 0.044 14.2 0.4 0.053 14.0 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX96789.1 - 0.1 12.6 11.9 0.11 12.5 11.9 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX96789.1 - 0.4 11.1 5.7 0.46 10.9 5.7 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PapD_N PF00345.20 EAX96790.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX96790.1 - 0.049 13.6 0.7 0.072 13.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX96791.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX96791.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Trypan_PARP PF05887.11 EAX96792.1 - 0.092 12.7 7.6 0.14 12.1 7.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX96793.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX96793.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pkinase PF00069.25 EAX96795.1 - 4.1e-64 216.5 0.0 6.4e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96795.1 - 3.9e-42 144.3 0.0 5.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96795.1 - 7.1e-07 28.8 0.0 1.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX96795.1 - 8.4e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX96795.1 - 0.00024 21.1 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX96795.1 - 0.00085 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX96795.1 - 0.0067 16.1 1.1 0.091 12.4 0.1 2.6 2 2 1 3 3 3 1 RIO1 family FTA2 PF13095.6 EAX96795.1 - 0.049 13.2 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 EAX96795.1 - 0.1 12.2 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Myb_DNA-binding PF00249.31 EAX96796.1 - 1.4e-30 105.2 2.2 1.4e-14 54.0 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96796.1 - 4.2e-26 91.0 6.0 1.8e-17 63.3 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96796.1 - 5e-08 32.7 2.3 0.005 16.7 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX96796.1 - 4.7e-05 23.4 0.5 0.13 12.3 0.1 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX96796.1 - 6e-05 23.2 1.1 0.00038 20.6 0.2 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX96796.1 - 0.0032 17.8 6.5 0.69 10.3 1.0 3.0 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF4177 PF13783.6 EAX96796.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) ZapA PF05164.13 EAX96796.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapA DHHC PF01529.20 EAX96797.1 - 4.1e-20 72.2 4.4 4.1e-20 72.2 4.4 1.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Presenilin PF01080.17 EAX96797.1 - 0.19 10.5 3.7 0.24 10.1 3.7 1.1 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 EAX96798.1 - 0.5 9.0 4.0 0.15 10.8 0.5 1.9 2 0 0 2 2 2 0 Cytochrome P450 Beach PF02138.18 EAX96799.1 - 3.2e-97 325.2 2.8 3.2e-97 325.2 2.8 3.2 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 EAX96799.1 - 8.4e-15 54.7 0.9 8.4e-15 54.7 0.9 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 EAX96799.1 - 3.4e-07 29.8 0.3 3.4e-07 29.8 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) PH_BEACH PF14844.6 EAX96799.1 - 0.0019 18.2 0.2 0.0059 16.7 0.2 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EAX96799.1 - 0.0082 17.0 0.4 6.9 7.7 0.1 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Laminin_G_3 PF13385.6 EAX96799.1 - 0.053 13.7 0.7 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily ABC_tran PF00005.27 EAX96800.1 - 6.8e-25 88.2 0.0 1.4e-24 87.1 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EAX96800.1 - 3.6e-12 46.7 0.8 0.00011 22.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAX96800.1 - 1.9e-05 25.2 0.3 5.3e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EAX96800.1 - 5.7e-05 22.7 0.1 0.0008 18.9 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAX96800.1 - 7.2e-05 22.4 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EAX96800.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 EAX96800.1 - 0.003 17.9 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX96800.1 - 0.0044 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EAX96800.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAX96800.1 - 0.0078 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAX96800.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAX96800.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX96800.1 - 0.013 14.6 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 EAX96800.1 - 0.017 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EAX96800.1 - 0.022 14.7 0.1 0.066 13.2 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EAX96800.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX96800.1 - 0.028 14.2 0.0 0.067 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 EAX96800.1 - 0.032 14.1 0.1 0.084 12.8 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 EAX96800.1 - 0.047 13.3 0.1 0.097 12.3 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 EAX96800.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EAX96800.1 - 0.076 13.4 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EAX96800.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAX96800.1 - 0.077 12.7 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EAX96800.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAX96800.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EAX96800.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 EAX96800.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EAX96800.1 - 0.16 12.2 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EAX96800.1 - 0.16 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF815 PF05673.13 EAX96800.1 - 0.18 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2070 PF09843.9 EAX96800.1 - 3.4 5.9 14.6 4.8 5.3 14.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gly_rich PF12810.7 EAX96801.1 - 5.2e-36 124.8 34.1 6e-36 124.6 34.1 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3309 PF11752.8 EAX96801.1 - 7 6.8 6.9 20 5.4 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Ank_4 PF13637.6 EAX96802.1 - 1.6e-52 175.2 18.6 2.7e-10 40.6 0.0 8.2 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX96802.1 - 1.6e-47 160.0 11.8 1.8e-12 47.7 1.9 5.7 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96802.1 - 4.3e-45 150.3 4.5 4.5e-07 30.0 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAX96802.1 - 1.1e-44 149.9 21.6 2.1e-11 43.8 0.2 7.0 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96802.1 - 3.2e-38 125.4 12.4 0.00016 21.8 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat DUF3447 PF11929.8 EAX96802.1 - 2e-32 111.0 3.5 2e-32 111.0 3.5 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) SF1-HH PF16275.5 EAX96803.1 - 0.00041 20.7 0.1 0.00064 20.0 0.1 1.4 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain Chlam_PMP PF02415.17 EAX96804.1 - 6.4e-09 35.8 26.7 0.065 13.7 0.4 7.6 6 0 0 6 6 6 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF2207 PF09972.9 EAX96804.1 - 0.021 13.6 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytomega_TRL10 PF06084.11 EAX96804.1 - 0.11 12.5 0.2 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF4774 PF15999.5 EAX96804.1 - 1.1 9.1 8.5 0.47 10.3 4.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4774) DUF3781 PF12636.7 EAX96805.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX96806.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX96806.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAX96807.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX96807.1 - 0.052 13.5 0.4 0.077 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX96808.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX96808.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3839 PF12943.7 EAX96809.1 - 2.1e-153 508.7 11.1 2.6e-153 508.4 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96809.1 - 0.033 14.7 1.4 0.12 12.9 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96809.1 - 0.06 13.8 2.8 2 8.9 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX96809.1 - 0.081 13.2 1.7 23 5.4 0.2 3.8 3 1 1 4 4 4 0 Tup N-terminal THOC7 PF05615.13 EAX96809.1 - 0.17 12.1 2.2 0.18 12.1 0.4 2.1 2 1 0 2 2 2 0 Tho complex subunit 7 DUF2408 PF10303.9 EAX96809.1 - 0.47 11.0 6.0 0.12 13.0 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAX96810.1 - 1.4e-40 137.6 0.6 2.8e-40 136.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX96810.1 - 0.0062 17.1 0.3 0.025 15.2 0.0 2.1 3 0 0 3 3 3 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX96811.1 - 1.3e-06 28.1 3.7 1.3e-06 28.1 3.7 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX96811.1 - 4.1e-05 23.9 0.2 0.00025 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX96811.1 - 0.00018 21.5 3.2 0.00045 20.3 3.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX96811.1 - 0.0002 21.1 0.3 0.39 10.4 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX96811.1 - 0.00081 19.2 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX96811.1 - 0.0011 18.8 0.3 0.0018 18.1 0.3 1.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX96811.1 - 0.0022 17.7 0.4 0.013 15.2 0.2 2.0 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX96811.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAX96811.1 - 0.05 14.0 0.1 0.39 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX96811.1 - 0.068 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX96811.1 - 0.068 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Elong_Iki1 PF10483.9 EAX96811.1 - 0.077 12.5 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 PhoH PF02562.16 EAX96811.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2897 PF11446.8 EAX96812.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX96813.1 - 9.8e-31 106.6 0.8 1.1e-30 106.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX96813.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Response_reg PF00072.24 EAX96814.1 - 1.4e-16 60.6 0.1 3.2e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 EAX96814.1 - 0.043 14.1 0.1 6.2 7.2 0.0 3.2 3 0 0 3 3 3 0 PAS fold UCH_N PF16674.5 EAX96814.1 - 0.056 13.4 0.5 0.3 11.0 0.5 2.3 1 0 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 APA3_viroporin PF11289.8 EAX96815.1 - 0.025 14.1 1.0 0.035 13.7 1.0 1.2 1 0 0 1 1 1 0 Coronavirus accessory protein 3a TPR_MLP1_2 PF07926.12 EAX96816.1 - 0.0049 16.9 12.9 0.014 15.4 12.9 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_Mu_Gam PF07352.12 EAX96816.1 - 0.0071 16.3 9.4 0.0087 16.0 9.4 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Apolipoprotein PF01442.18 EAX96816.1 - 0.019 14.8 3.7 0.024 14.5 3.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Nup88 PF10168.9 EAX96816.1 - 0.033 12.0 10.1 0.036 11.9 10.1 1.0 1 0 0 1 1 1 0 Nuclear pore component APG17 PF04108.12 EAX96816.1 - 0.04 13.0 7.2 0.047 12.8 7.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 AAA_13 PF13166.6 EAX96816.1 - 0.053 12.2 7.8 0.06 12.0 7.8 1.0 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.21 EAX96816.1 - 0.088 12.4 14.6 0.099 12.2 14.6 1.0 1 0 0 1 1 1 0 Snf7 Spc7 PF08317.11 EAX96816.1 - 0.14 11.0 12.1 0.16 10.8 12.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Perilipin PF03036.16 EAX96816.1 - 0.17 10.9 7.1 0.19 10.7 7.1 1.0 1 0 0 1 1 1 0 Perilipin family DUF4616 PF15394.6 EAX96816.1 - 0.24 10.3 2.9 0.26 10.2 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) RmuC PF02646.16 EAX96816.1 - 0.24 10.5 10.1 0.3 10.2 10.1 1.1 1 0 0 1 1 1 0 RmuC family T4_Rnl2_C PF18043.1 EAX96816.1 - 0.28 11.4 8.3 0.62 10.2 8.3 1.7 1 1 0 1 1 1 0 T4 RNA ligase 2 C-terminal ZapB PF06005.12 EAX96816.1 - 0.3 11.5 13.5 1.3 9.6 3.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 EAX96816.1 - 0.55 10.6 8.5 0.23 11.8 3.5 2.3 1 1 2 3 3 3 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 EAX96816.1 - 1 8.9 5.8 1.1 8.8 5.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.6 EAX96816.1 - 1.2 9.3 9.3 3.7 7.7 1.9 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain PRP1_N PF06424.12 EAX96816.1 - 1.6 9.1 7.7 2.7 8.4 7.7 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal CENP-H PF05837.12 EAX96816.1 - 2.9 8.3 12.1 2.9 8.3 3.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 EAX96816.1 - 3 8.0 10.4 2.6 8.2 0.4 2.6 2 1 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 EAX96816.1 - 6.8 7.4 11.2 21 5.8 2.7 2.6 1 1 2 3 3 3 0 SlyX HrpB7 PF09486.10 EAX96817.1 - 3e-06 27.7 14.3 0.002 18.6 3.5 3.3 2 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB7) MAD PF05557.13 EAX96817.1 - 6.2e-06 24.9 43.1 1.1e-05 24.0 43.1 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3584 PF12128.8 EAX96817.1 - 0.00038 18.1 36.1 0.00067 17.3 36.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GAS PF13851.6 EAX96817.1 - 0.0017 17.8 49.4 0.015 14.6 25.0 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EAX96817.1 - 0.0023 18.4 47.8 0.016 15.7 22.8 3.3 1 1 1 3 3 3 2 Fez1 Rab5-bind PF09311.11 EAX96817.1 - 0.0039 16.6 11.9 0.0039 16.6 11.9 3.7 1 1 2 3 3 3 2 Rabaptin-like protein TPR_MLP1_2 PF07926.12 EAX96817.1 - 0.0039 17.2 48.7 0.29 11.2 11.7 4.8 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EAX96817.1 - 0.0041 17.2 50.2 0.1 12.6 11.7 4.7 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding Filament PF00038.21 EAX96817.1 - 0.0096 15.5 46.3 0.39 10.3 8.4 3.3 1 1 2 3 3 3 3 Intermediate filament protein Spc7 PF08317.11 EAX96817.1 - 0.014 14.3 49.6 0.048 12.6 21.0 3.2 1 1 3 4 4 4 0 Spc7 kinetochore protein TSC22 PF01166.18 EAX96817.1 - 0.056 13.8 0.1 0.056 13.8 0.1 6.3 6 1 1 7 7 7 0 TSC-22/dip/bun family ZapB PF06005.12 EAX96817.1 - 0.073 13.5 52.6 0.23 11.9 5.5 6.5 2 2 3 6 6 6 0 Cell division protein ZapB ATG16 PF08614.11 EAX96817.1 - 0.073 13.3 48.0 0.036 14.3 18.9 4.0 2 1 2 4 4 3 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EAX96817.1 - 0.095 11.9 42.4 1.9 7.6 23.8 3.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region kleA_kleC PF17383.2 EAX96817.1 - 0.11 12.8 1.5 1.4 9.3 0.1 3.2 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF4404 PF14357.6 EAX96817.1 - 0.12 13.1 0.1 0.12 13.1 0.1 5.9 3 1 4 7 7 7 0 Domain of unknown function (DUF4404) Val_tRNA-synt_C PF10458.9 EAX96817.1 - 0.14 12.4 0.2 0.14 12.4 0.2 4.9 5 1 0 6 6 5 0 Valyl tRNA synthetase tRNA binding arm HMMR_N PF15905.5 EAX96817.1 - 0.18 11.3 53.7 0.3 10.5 18.4 3.9 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 EAX96817.1 - 0.43 10.3 41.7 0.078 12.8 11.7 3.4 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EAX96817.1 - 0.49 10.5 45.1 0.043 13.9 15.1 4.2 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain DUF5082 PF16888.5 EAX96817.1 - 0.51 10.6 43.7 0.16 12.3 12.6 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 EAX96817.1 - 0.55 10.3 49.3 0.79 9.8 14.0 5.0 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.6 EAX96817.1 - 2.7 6.5 50.1 0.24 10.0 14.9 2.3 2 1 1 3 3 3 0 AAA domain Atg14 PF10186.9 EAX96817.1 - 2.7 7.0 46.0 0.22 10.6 6.8 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 EAX96817.1 - 4.7 6.8 58.3 0.36 10.5 21.1 5.0 2 2 3 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease Bacillus_HBL PF05791.11 EAX96817.1 - 5 6.9 46.3 0.059 13.2 9.7 5.0 1 1 4 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) FmiP_Thoc5 PF09766.9 EAX96817.1 - 5.1 6.3 42.9 0.29 10.4 8.9 3.0 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 CLZ PF16526.5 EAX96817.1 - 5.2 7.5 29.7 0.077 13.4 1.4 5.5 2 1 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 EAX96817.1 - 5.3 7.4 24.6 7.6 6.9 0.6 5.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 EAX96817.1 - 5.9 6.4 40.2 9.3 5.7 20.1 2.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EAX96817.1 - 6.7 6.8 34.5 3.6 7.6 4.7 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 EAX96817.1 - 8.7 6.8 49.8 0.081 13.3 6.7 4.9 2 1 2 5 5 5 0 Centromere protein H (CENP-H) Chromo PF00385.24 EAX96818.1 - 3.9e-12 45.9 1.2 8.3e-12 44.8 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Abhydrolase_1 PF00561.20 EAX96819.1 - 0.00036 20.3 0.1 0.019 14.6 0.0 2.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EAX96819.1 - 0.0029 17.4 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EAX96819.1 - 0.022 15.3 0.0 0.048 14.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAX96819.1 - 0.03 13.6 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf_CCCH_4 PF18345.1 EAX96820.1 - 1.5e-06 28.0 0.8 3.3e-06 27.0 0.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAX96820.1 - 2.1e-06 27.4 0.4 4.2e-06 26.4 0.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EAX96820.1 - 0.00052 19.8 0.4 0.0012 18.7 0.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAX96820.1 - 0.0064 17.2 1.0 0.017 15.8 1.0 1.8 1 1 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 EAX96820.1 - 2.8 8.6 5.1 0.54 10.8 0.9 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CMD PF02627.20 EAX96821.1 - 5e-08 32.9 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family A_thal_3526 PF09713.10 EAX96821.1 - 0.73 10.1 4.6 3.5 8.0 1.1 2.8 2 1 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Pkinase PF00069.25 EAX96822.1 - 3.4e-26 92.2 0.0 7.7e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96822.1 - 1.3e-10 41.0 0.0 2.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX96822.1 - 2.7e-08 33.0 0.0 2.7e-08 33.0 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EAX96822.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family UPF0242 PF06785.11 EAX96823.1 - 0.012 15.7 31.7 0.023 14.8 5.1 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_C PF15908.5 EAX96823.1 - 0.045 14.0 22.1 0.044 14.0 2.4 3.7 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal ZapB PF06005.12 EAX96823.1 - 0.084 13.3 0.3 0.084 13.3 0.3 4.8 2 1 2 4 4 4 0 Cell division protein ZapB YabA PF06156.13 EAX96823.1 - 0.085 13.5 23.7 0.64 10.7 0.3 4.0 2 1 1 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 EAX96823.1 - 0.24 11.9 0.0 0.24 11.9 0.0 4.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Speriolin_N PF15058.6 EAX96823.1 - 0.33 11.0 1.9 5.6 7.0 0.2 2.6 2 1 0 2 2 2 0 Speriolin N terminus DivIC PF04977.15 EAX96823.1 - 0.34 10.7 19.1 3.9 7.3 2.5 4.7 3 1 1 4 4 4 0 Septum formation initiator GIT_CC PF16559.5 EAX96823.1 - 1.1 9.2 8.6 7.7 6.5 1.3 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc24 PF08286.11 EAX96823.1 - 1.8 8.8 28.2 8.7 6.6 9.0 3.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 MCC-bdg_PDZ PF10506.9 EAX96823.1 - 2.6 8.1 16.5 1.2 9.2 0.9 4.1 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3450 PF11932.8 EAX96823.1 - 3.2 7.0 21.9 0.9 8.8 3.3 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EAX96823.1 - 5.6 7.0 41.1 4.3 7.3 1.1 4.3 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4999 PF16390.5 EAX96825.1 - 0.083 13.1 5.0 6.8 7.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function Spc7 PF08317.11 EAX96826.1 - 0.0062 15.5 130.0 0.042 12.7 20.4 7.1 1 1 7 8 8 8 7 Spc7 kinetochore protein DUF641 PF04859.12 EAX96826.1 - 0.016 15.5 6.0 0.016 15.5 6.0 8.9 2 2 5 7 7 7 0 Plant protein of unknown function (DUF641) Tugs PF17840.1 EAX96826.1 - 0.58 10.4 3.4 17 5.7 0.1 3.8 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain AvrLm4-7 PF18661.1 EAX96826.1 - 2.8 9.0 10.4 3.5 8.7 0.7 4.2 3 0 0 3 3 3 0 Avirulence Effector AvrLm4-7 PdaC PF13739.6 EAX96827.1 - 0.087 13.8 0.8 0.18 12.8 0.8 1.5 1 0 0 1 1 1 0 Deacetylase PdaC PSP PF04046.16 EAX96828.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96829.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX96831.1 - 0.022 15.2 0.7 0.043 14.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX96832.1 - 5.4e-158 523.7 13.5 6.6e-158 523.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX96832.1 - 0.035 14.6 1.2 0.21 12.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96832.1 - 0.44 11.0 6.9 2.4 8.7 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX96832.1 - 0.5 10.9 5.3 0.26 11.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MULE PF10551.9 EAX96833.1 - 2.6e-09 37.4 0.3 6.9e-09 36.0 0.3 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX96833.1 - 0.033 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF1493 PF07377.12 EAX96834.1 - 0.095 13.2 0.7 0.24 11.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX96835.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96836.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX96837.1 - 1.4e-239 775.4 76.5 7.4e-19 68.1 0.5 14.3 2 1 16 18 18 18 18 Ankyrin repeats (3 copies) Ank PF00023.30 EAX96837.1 - 3.4e-184 590.1 23.0 1.4e-08 34.8 0.0 21.2 21 0 0 21 21 21 20 Ankyrin repeat Ank_4 PF13637.6 EAX96837.1 - 3.7e-164 531.2 46.9 9.2e-14 51.6 0.1 21.1 3 1 18 21 21 21 20 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX96837.1 - 8.5e-151 471.3 28.3 1.7e-06 27.9 0.0 22.1 23 0 0 23 23 22 18 Ankyrin repeat Ank_5 PF13857.6 EAX96837.1 - 3.9e-139 450.9 41.7 3.6e-13 49.5 0.1 13.5 5 2 10 16 16 16 15 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96837.1 - 2e-38 130.2 4.4 2e-38 130.2 4.4 3.1 2 0 0 2 2 1 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX96837.1 - 1.1e-16 60.8 0.0 0.26 11.6 0.0 9.7 1 1 12 14 14 14 3 N terminal of Calcineurin-like phosphoesterase CEP44 PF15007.6 EAX96837.1 - 1.5e-11 44.5 0.0 1.1e+02 3.0 0.0 12.7 9 6 7 16 16 16 0 Centrosomal spindle body, CEP44 ThiS-like PF14453.6 EAX96837.1 - 4.5e-11 42.6 29.8 21 5.3 0.0 16.8 8 5 10 18 18 18 0 ThiS-like ubiquitin Mqo PF06039.15 EAX96837.1 - 6.1e-08 31.7 3.3 7.2 5.0 0.0 8.8 1 1 10 12 12 12 1 Malate:quinone oxidoreductase (Mqo) PH_8 PF15409.6 EAX96837.1 - 1.3e-06 28.5 14.4 82 3.6 0.0 11.8 1 1 14 16 16 16 0 Pleckstrin homology domain Phage_G PF02306.15 EAX96837.1 - 6.7e-06 25.9 6.0 8.4 6.1 0.0 8.0 1 1 9 11 11 11 1 Major spike protein (G protein) DUF3012 PF11216.8 EAX96837.1 - 1.4 9.0 15.6 1.6e+02 2.5 0.1 7.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3012) DUF1604 PF07713.13 EAX96837.1 - 4.7 7.1 10.6 12 5.8 0.0 5.9 8 2 0 8 8 7 0 Protein of unknown function (DUF1604) DUF5578 PF17741.1 EAX96838.1 - 0.073 12.5 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Pkinase PF00069.25 EAX96839.1 - 0.0013 18.2 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EAX96840.1 - 0.041 13.3 0.0 0.048 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Beta_helix PF13229.6 EAX96842.1 - 0.0011 18.8 4.6 0.29 11.0 2.4 3.1 2 1 0 2 2 2 2 Right handed beta helix region Pentapeptide_4 PF13599.6 EAX96842.1 - 0.7 10.1 4.6 1.6 9.0 0.4 3.3 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) ICMT PF04140.14 EAX96843.1 - 2e-24 85.9 0.3 3.6e-24 85.0 0.3 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAX96843.1 - 8.6e-12 45.4 1.5 2.8e-11 43.7 0.4 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EAX96843.1 - 1.2e-06 28.2 0.1 2e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EAX96843.1 - 0.0016 18.0 0.1 0.0076 15.8 0.0 1.9 2 0 0 2 2 2 1 NnrU protein DUF2273 PF10031.9 EAX96843.1 - 0.046 13.7 0.6 0.046 13.7 0.6 3.4 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) Trep_Strep PF09605.10 EAX96843.1 - 0.053 13.5 0.2 0.053 13.5 0.2 2.3 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PhaG_MnhG_YufB PF03334.14 EAX96843.1 - 0.75 10.1 5.2 7.3 6.9 1.4 2.9 2 1 0 2 2 2 0 Na+/H+ antiporter subunit Myb_DNA-binding PF00249.31 EAX96844.1 - 3.6e-46 155.1 8.2 2.8e-17 62.6 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96844.1 - 2.8e-37 126.7 1.9 3.8e-13 49.5 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96844.1 - 8.1e-07 28.9 0.8 0.0014 18.5 0.0 3.4 1 1 2 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX96844.1 - 1.4e-06 28.4 1.1 0.083 13.1 0.0 3.3 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX96844.1 - 6.8e-06 26.1 0.1 0.44 10.6 0.0 3.3 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 EAX96844.1 - 3e-05 24.0 2.6 0.015 15.4 0.2 3.0 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX96844.1 - 0.0009 19.4 3.0 0.36 11.1 0.1 3.7 2 1 1 3 3 3 1 Rap1 Myb domain Spore_III_AB PF09548.10 EAX96844.1 - 0.14 12.3 0.1 20 5.2 0.0 2.6 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EAX96844.1 - 0.36 11.2 13.4 2 8.8 0.4 5.0 3 3 0 3 3 3 0 Myb/SANT-like DNA-binding domain AAA_13 PF13166.6 EAX96845.1 - 0.00097 17.9 7.4 0.0013 17.5 7.4 1.1 1 0 0 1 1 1 1 AAA domain Snapin_Pallidin PF14712.6 EAX96845.1 - 0.0037 17.7 5.0 0.0066 16.8 5.0 1.5 1 0 0 1 1 1 1 Snapin/Pallidin HrpB7 PF09486.10 EAX96845.1 - 0.0038 17.6 1.6 0.0058 17.0 1.6 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) TRPM_tetra PF16519.5 EAX96845.1 - 0.005 16.9 6.0 0.032 14.3 0.6 3.0 3 0 0 3 3 3 1 Tetramerisation domain of TRPM Baculo_PEP_C PF04513.12 EAX96845.1 - 0.0052 16.8 0.3 0.009 16.1 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2570 PF10828.8 EAX96845.1 - 0.0054 16.5 5.1 0.011 15.5 5.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Spc29 PF17082.5 EAX96845.1 - 0.0066 16.3 3.9 0.0091 15.9 3.9 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 TACC_C PF05010.14 EAX96845.1 - 0.0083 15.9 8.6 0.012 15.4 8.6 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_I PF06008.14 EAX96845.1 - 0.0084 15.8 4.0 0.012 15.3 4.0 1.2 1 0 0 1 1 1 1 Laminin Domain I FTO_CTD PF12934.7 EAX96845.1 - 0.0094 15.7 2.4 0.017 14.9 2.4 1.4 1 0 0 1 1 1 1 FTO C-terminal domain ZapB PF06005.12 EAX96845.1 - 0.014 15.8 7.9 0.037 14.5 7.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB PCRF PF03462.18 EAX96845.1 - 0.022 14.6 4.2 0.031 14.2 4.2 1.3 1 0 0 1 1 1 0 PCRF domain DUF16 PF01519.16 EAX96845.1 - 0.025 15.1 5.8 0.053 14.0 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Atg14 PF10186.9 EAX96845.1 - 0.033 13.3 7.1 0.05 12.7 7.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 EAX96845.1 - 0.036 14.4 5.5 0.041 14.2 3.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein TMPIT PF07851.13 EAX96845.1 - 0.04 13.2 4.8 0.053 12.8 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 EAX96845.1 - 0.045 13.8 3.9 0.12 12.5 3.9 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4404 PF14357.6 EAX96845.1 - 0.046 14.3 2.2 0.097 13.3 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Laminin_II PF06009.12 EAX96845.1 - 0.047 13.7 6.1 0.072 13.1 5.2 1.8 1 1 0 1 1 1 0 Laminin Domain II BLOC1_2 PF10046.9 EAX96845.1 - 0.051 13.9 9.1 0.23 11.8 3.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EAX96845.1 - 0.052 12.4 11.5 0.15 10.9 11.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Med30 PF11315.8 EAX96845.1 - 0.052 13.7 6.6 0.092 12.9 6.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 30 Tup_N PF08581.10 EAX96845.1 - 0.055 13.8 12.9 0.095 13.0 9.4 2.3 1 1 1 2 2 2 0 Tup N-terminal DUF724 PF05266.14 EAX96845.1 - 0.072 12.9 9.3 0.11 12.4 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EAX96845.1 - 0.072 13.1 9.0 0.14 12.2 8.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EAX96845.1 - 0.082 13.4 6.9 0.15 12.6 6.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region FliD_N PF02465.18 EAX96845.1 - 0.085 13.6 3.2 0.1 13.3 1.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Hemagglutinin PF00509.18 EAX96845.1 - 0.18 10.1 3.2 0.21 9.9 3.2 1.1 1 0 0 1 1 1 0 Haemagglutinin RPW8 PF05659.11 EAX96845.1 - 0.19 11.4 9.1 1.3 8.7 4.7 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF641 PF04859.12 EAX96845.1 - 0.22 11.8 6.3 0.45 10.9 6.3 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.6 EAX96845.1 - 0.24 11.8 13.3 3.2 8.2 13.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 EAX96845.1 - 0.24 11.3 12.8 1.5 8.8 3.1 3.0 1 1 2 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 EAX96845.1 - 0.28 11.6 13.3 0.5 10.8 5.1 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CdvA PF18822.1 EAX96845.1 - 0.31 10.9 13.4 0.044 13.6 7.8 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Spc24 PF08286.11 EAX96845.1 - 0.31 11.3 9.4 3.4 8.0 9.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 EAX96845.1 - 0.45 10.9 9.9 13 6.2 0.1 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2203 PF09969.9 EAX96845.1 - 0.48 11.2 4.6 0.84 10.4 4.6 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.12 EAX96845.1 - 0.71 10.4 5.9 5.4 7.6 5.2 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.6 EAX96845.1 - 1.7 9.1 5.6 3.5 8.1 4.9 1.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 EAX96845.1 - 1.7 8.2 5.2 2.1 7.9 4.0 1.6 1 1 0 1 1 1 0 fzo-like conserved region DivIC PF04977.15 EAX96845.1 - 2.9 7.7 8.4 5.8 6.8 4.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Taxilin PF09728.9 EAX96845.1 - 2.9 7.0 14.3 0.87 8.7 6.8 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein zf-C4H2 PF10146.9 EAX96845.1 - 5 7.4 12.4 7 6.9 12.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4446 PF14584.6 EAX96845.1 - 7.3 6.6 9.3 81 3.2 9.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Pam16 PF03656.13 EAX96846.1 - 2.7e-07 30.6 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 RAMA PF18755.1 EAX96847.1 - 0.011 16.1 9.3 0.19 12.1 0.9 2.9 1 1 2 3 3 3 0 Restriction Enzyme Adenine Methylase Associated Protein_K PF12283.8 EAX96847.1 - 0.033 14.4 5.3 16 5.8 0.1 3.5 1 1 3 4 4 4 0 Bacteriophage protein K Tox-REase-3 PF15647.6 EAX96847.1 - 0.97 9.7 13.9 2.4 8.5 3.9 2.9 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 3 PorB PF11565.8 EAX96847.1 - 1.7 9.1 13.3 3.5 8.1 3.5 3.8 1 1 3 4 4 4 0 Alpha helical Porin B PsaN PF05479.11 EAX96847.1 - 4.4 7.5 24.2 1.7 8.8 2.4 4.1 1 1 4 5 5 5 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF2756 PF10956.8 EAX96847.1 - 7.9 7.0 11.6 2.3 8.8 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2756) DUF3951 PF13131.6 EAX96848.1 - 0.075 13.2 1.1 0.15 12.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF3377 PF11857.8 EAX96848.1 - 0.082 12.9 0.0 0.082 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CoxIIa PF08113.11 EAX96848.1 - 0.9 9.4 4.9 1.6 8.6 4.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DUF2254 PF10011.9 EAX96848.1 - 0.95 8.2 3.8 1.6 7.5 1.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF4446 PF14584.6 EAX96848.1 - 1.6 8.7 11.2 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Peptidase_C69 PF03577.15 EAX96849.1 - 0.0093 14.9 0.2 0.011 14.7 0.2 1.0 1 0 0 1 1 1 1 Peptidase family C69 Cnn_1N PF07989.11 EAX96850.1 - 0.065 13.4 0.3 0.065 13.4 0.3 12.6 7 4 5 12 12 12 0 Centrosomin N-terminal motif 1 LysM PF01476.20 EAX96850.1 - 0.075 13.1 0.4 0.79 9.8 0.4 3.0 1 0 0 1 1 1 0 LysM domain ARPC4 PF05856.12 EAX96851.1 - 1.1e-69 233.4 5.2 1.2e-69 233.2 5.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.14 EAX96851.1 - 0.0015 18.3 1.8 0.0077 16.0 0.2 2.0 1 1 1 2 2 2 1 Arp2/3 complex, 34 kD subunit p34-Arc Brr6_like_C_C PF10104.9 EAX96851.1 - 0.0088 15.8 0.3 0.016 15.0 0.3 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain COPIIcoated_ERV PF07970.12 EAX96852.1 - 6.8e-37 127.5 0.1 8.9e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX96852.1 - 9.9e-15 54.7 0.8 1.7e-14 53.9 0.8 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CLASP_N PF12348.8 EAX96853.1 - 3.7e-33 115.0 13.1 1.7e-29 103.0 2.4 3.8 3 1 0 3 3 3 3 CLASP N terminal Cnd1 PF12717.7 EAX96853.1 - 2.2e-05 24.6 7.5 0.0033 17.5 0.1 4.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX96853.1 - 0.011 16.0 0.1 0.011 16.0 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat Condensin2nSMC PF12422.8 EAX96853.1 - 0.13 12.5 0.6 30 4.8 0.1 3.4 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit LRR_5 PF13306.6 EAX96854.1 - 1.8e-60 202.5 39.6 1.5e-32 112.2 12.7 3.5 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96854.1 - 8.3e-12 44.7 3.5 0.00053 19.7 0.0 5.5 2 2 5 7 7 7 6 Leucine rich repeat ATG16 PF08614.11 EAX96856.1 - 6.6e-05 23.2 29.1 6.6e-05 23.2 29.1 9.1 2 1 5 7 7 7 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EAX96856.1 - 7.7e-05 21.6 39.5 7.7e-05 21.6 39.5 6.8 2 1 6 8 8 8 3 AAA domain Tudor_RapA PF18337.1 EAX96856.1 - 0.19 11.9 8.2 2.8 8.2 0.3 4.0 3 0 0 3 3 3 0 RapA N-terminal Tudor like domain Thg1 PF04446.12 EAX96857.1 - 8.8e-47 158.2 0.1 1.3e-46 157.7 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EAX96857.1 - 2.1e-25 89.3 1.3 2.8e-25 88.9 0.6 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Xpo1 PF08389.12 EAX96857.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.6 1 1 0 1 1 1 0 Exportin 1-like protein F-actin_cap_A PF01267.17 EAX96858.1 - 1.2e-51 175.8 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F-actin_cap_A PF01267.17 EAX96859.1 - 1.2e-51 175.8 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit zf-RING_2 PF13639.6 EAX96861.1 - 0.0016 18.7 13.8 0.0026 18.0 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EAX96861.1 - 0.5 10.3 13.7 1 9.3 13.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2HC5 PF06221.13 EAX96861.1 - 3.5 7.7 14.9 11 6.2 9.8 2.3 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Ank_2 PF12796.7 EAX96862.1 - 9.4e-127 413.9 87.0 6.1e-19 68.4 5.1 9.9 3 1 10 13 13 13 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96862.1 - 3.5e-88 288.9 37.2 5.6e-12 45.9 0.2 13.8 3 1 11 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 EAX96862.1 - 9e-67 218.8 42.2 6.1e-07 29.6 0.3 13.8 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.6 EAX96862.1 - 8.8e-64 203.9 26.8 2e-05 24.6 0.1 15.2 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 EAX96862.1 - 1e-55 185.0 19.4 9.6e-10 38.5 0.1 9.4 6 1 4 11 11 11 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96862.1 - 1e-19 70.3 3.1 1e-19 70.3 3.1 5.7 6 3 1 7 7 7 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX96862.1 - 1.5e-05 25.0 21.7 6.4 7.0 0.1 9.3 6 4 5 11 11 11 3 Protein of unknown function (DUF3718) Herpes_UL36 PF03586.13 EAX96862.1 - 0.0092 15.3 6.8 23 4.2 0.1 6.1 3 2 4 8 8 8 0 Herpesvirus UL36 tegument protein PrmC_N PF17827.1 EAX96862.1 - 0.035 14.7 7.7 2.2e+02 2.5 0.0 7.6 6 3 3 9 9 9 0 PrmC N-terminal domain DUF1103 PF06513.11 EAX96862.1 - 3.5 7.2 23.2 0.37 10.4 3.1 3.3 2 1 2 4 4 4 0 Repeat of unknown function (DUF1103) P2_Phage_GpR PF06891.11 EAX96862.1 - 3.5 7.7 6.4 1.5e+02 2.4 0.2 5.1 2 2 4 7 7 7 0 P2 phage tail completion protein R (GpR) IL15 PF02372.15 EAX96863.1 - 0.1 12.6 3.0 0.23 11.5 2.4 1.7 1 1 1 2 2 2 0 Interleukin 15 SRP-alpha_N PF04086.13 EAX96864.1 - 1.3 8.9 35.4 2.2 8.2 35.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RXT2_N PF08595.11 EAX96865.1 - 5.3 7.1 16.5 0.047 13.7 4.7 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal Got1 PF04178.12 EAX96866.1 - 4.4e-22 78.6 16.3 5.2e-22 78.4 16.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ETRAMP PF09716.10 EAX96866.1 - 1.3 9.1 5.5 1 9.5 2.8 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF202 PF02656.15 EAX96866.1 - 3.3 8.2 6.4 15 6.2 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2070 PF09843.9 EAX96866.1 - 4.1 5.6 9.4 5 5.3 9.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RPAP3_C PF13877.6 EAX96867.1 - 0.01 16.3 1.8 1.7 9.3 0.0 4.1 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 FANCI_S2 PF14676.6 EAX96867.1 - 0.59 10.4 4.5 16 5.7 0.0 4.3 4 1 1 5 5 5 0 FANCI solenoid 2 Ras PF00071.22 EAX96868.1 - 1.1e-46 158.3 0.0 1.4e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96868.1 - 2.1e-29 102.2 0.0 2.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96868.1 - 5.9e-17 61.7 0.0 7e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX96868.1 - 7e-08 32.2 0.0 1e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX96868.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX96868.1 - 0.00016 21.8 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX96868.1 - 0.00018 21.0 0.0 0.0004 19.9 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX96868.1 - 0.00032 20.5 0.1 0.0026 17.5 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EAX96868.1 - 0.00063 19.7 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAX96868.1 - 0.0027 16.9 0.1 0.044 12.9 0.0 2.3 2 1 1 3 3 3 1 G-protein alpha subunit AAA_7 PF12775.7 EAX96868.1 - 0.0037 16.8 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAX96868.1 - 0.0089 16.3 0.1 0.021 15.1 0.1 1.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAX96868.1 - 0.046 14.1 0.1 0.089 13.2 0.0 1.7 2 1 0 2 2 1 0 RNA helicase AAA PF00004.29 EAX96868.1 - 0.069 13.6 0.0 0.19 12.1 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAX96868.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 EAX96868.1 - 0.11 12.1 0.1 0.85 9.2 0.0 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EAX96868.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_M42 PF05343.14 EAX96868.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase AAA_24 PF13479.6 EAX96868.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX96868.1 - 0.19 12.1 0.1 0.5 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EAX96868.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EAX96868.1 - 0.22 11.5 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Hist_deacetyl PF00850.19 EAX96869.1 - 1.9e-76 257.5 0.1 3.1e-76 256.8 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DAG_kinase_N PF14513.6 EAX96869.1 - 0.02 15.1 1.3 0.032 14.4 0.4 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF3949 PF13133.6 EAX96869.1 - 0.54 10.8 2.8 1.1 9.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) dsDNA_bind PF01984.20 EAX96872.1 - 5.9e-23 81.3 9.2 6.6e-23 81.1 9.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain zf-CCCH_3 PF15663.5 EAX96873.1 - 0.078 13.2 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger containing family LCAT PF02450.15 EAX96874.1 - 5.3e-29 101.6 0.0 6.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAX96874.1 - 0.005 16.1 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAX96874.1 - 0.043 13.4 0.0 1.6 8.3 0.0 2.2 2 1 1 3 3 3 0 alpha/beta hydrolase fold Rad60-SLD PF11976.8 EAX96875.1 - 0.0014 18.4 0.1 0.0037 17.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAX96875.1 - 0.0017 18.1 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EAX96875.1 - 0.017 15.4 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain PB1 PF00564.24 EAX96875.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 PB1 domain Dynein_light PF01221.18 EAX96876.1 - 2.4e-26 91.9 0.1 3e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Trypan_PARP PF05887.11 EAX96876.1 - 8.8 6.3 22.1 12 5.9 22.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.19 EAX96877.1 - 6.2e-07 29.7 3.9 1.2e-06 28.8 3.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX96877.1 - 0.00012 22.6 2.4 0.00026 21.5 2.4 1.6 1 0 0 1 1 1 1 HMG-box domain Bromodomain PF00439.25 EAX96878.1 - 2.5e-24 85.1 0.2 5.5e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX96878.1 - 2.1e-05 24.6 3.7 3.6e-05 23.9 2.6 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation AHD PF17793.1 EAX96878.1 - 0.0035 17.1 0.1 0.0091 15.8 0.1 1.7 1 0 0 1 1 1 1 ANC1 homology domain (AHD) FKBP_C PF00254.28 EAX96879.1 - 0.0013 19.1 0.1 0.043 14.1 0.0 2.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nbs1_C PF08599.10 EAX96879.1 - 4.3 7.5 7.9 0.21 11.8 0.5 2.7 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 zf-C3Hc3H PF13891.6 EAX96880.1 - 7.7e-07 29.4 8.2 7.7e-07 29.4 8.2 2.6 3 1 0 3 3 3 1 Potential DNA-binding domain Phage_min_cap2 PF06152.11 EAX96880.1 - 0.052 12.5 0.1 0.066 12.1 0.1 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF4625 PF15418.6 EAX96882.1 - 1.3e-11 44.9 3.4 0.0054 17.0 0.0 5.4 3 2 1 4 4 4 3 Domain of unknown function (DUF4625) Big_7 PF17957.1 EAX96882.1 - 2.9e-08 34.4 8.3 0.01 16.6 0.2 4.5 4 1 1 5 5 5 2 Bacterial Ig domain DUF4469 PF14734.6 EAX96882.1 - 4.9e-06 26.6 0.1 0.2 11.9 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4469) with IG-like fold G2F PF07474.12 EAX96882.1 - 8.6e-05 22.4 1.8 0.18 11.5 0.1 2.5 2 0 0 2 2 2 2 G2F domain DUF4832 PF16116.5 EAX96882.1 - 0.00044 20.2 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4832) Glyco_hydro_61 PF03443.14 EAX96882.1 - 0.0011 19.0 0.0 6.1 6.7 0.0 3.3 3 0 0 3 3 3 2 Glycosyl hydrolase family 61 Y_Y_Y PF07495.13 EAX96882.1 - 0.0028 17.6 0.5 4.4 7.3 0.0 4.1 3 0 0 3 3 3 1 Y_Y_Y domain UFC1 PF08694.11 EAX96882.1 - 0.0047 16.6 0.0 3.6 7.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-fold modifier-conjugating enzyme 1 E1_DerP2_DerF2 PF02221.15 EAX96882.1 - 0.027 14.9 0.1 24 5.4 0.0 3.4 2 1 1 3 3 3 0 ML domain Omp28 PF11551.8 EAX96882.1 - 0.044 13.6 0.1 0.55 10.1 0.0 2.9 4 0 0 4 4 4 0 Outer membrane protein Omp28 Fringe PF02434.16 EAX96883.1 - 5.1e-13 49.1 0.0 7.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like IL17_R_N PF15037.6 EAX96885.1 - 0.059 12.3 0.3 0.43 9.5 0.2 2.0 2 0 0 2 2 2 0 Interleukin-17 receptor extracellular region PTR PF12789.7 EAX96885.1 - 0.071 13.2 4.6 0.28 11.3 0.1 3.6 4 0 0 4 4 4 0 Phage tail repeat like DUF4795 PF16043.5 EAX96885.1 - 0.21 11.2 9.6 1.1 8.8 7.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YmaF PF12788.7 EAX96885.1 - 0.48 11.0 4.9 6.7 7.3 1.7 3.2 2 1 0 2 2 2 0 YmaF family Phage_fiber PF03335.13 EAX96885.1 - 5.5 7.4 11.3 30 5.2 0.9 3.6 3 0 0 3 3 3 0 Phage tail fibre repeat EF-hand_1 PF00036.32 EAX96887.1 - 3.8e-16 57.4 3.8 0.00064 19.1 0.0 3.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EAX96887.1 - 1.9e-14 52.3 0.1 0.00095 18.9 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EAX96887.1 - 2.4e-12 47.1 8.3 4.1e-09 36.8 0.1 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX96887.1 - 2e-10 39.6 4.4 0.00049 19.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EAX96887.1 - 1.2e-09 37.8 1.5 0.019 14.8 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EAX96887.1 - 0.18 11.8 0.8 0.42 10.6 0.1 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Lipoprotein_Ltp PF07553.11 EAX96887.1 - 0.34 11.2 2.3 1.7 9.0 0.1 3.1 4 1 0 4 4 4 0 Host cell surface-exposed lipoprotein Tub PF01167.18 EAX96888.1 - 0.00026 20.9 0.3 0.0032 17.3 0.1 2.3 1 1 1 2 2 2 1 Tub family Menin PF05053.13 EAX96888.1 - 1.7 6.9 4.8 2.1 6.6 4.8 1.1 1 0 0 1 1 1 0 Menin CarboxypepD_reg PF13620.6 EAX96889.1 - 6.7e-41 138.5 20.1 1.4e-07 31.6 0.0 9.6 8 2 1 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EAX96889.1 - 1.7e-16 60.4 13.5 0.12 12.7 0.0 9.0 7 2 2 9 9 9 6 SdrD B-like domain CarbopepD_reg_2 PF13715.6 EAX96889.1 - 5.7e-15 55.1 16.7 0.00046 20.1 0.0 8.4 9 0 0 9 9 9 5 CarboxypepD_reg-like domain DUF2012 PF09430.10 EAX96889.1 - 2.4e-12 47.0 4.9 0.05 13.7 0.0 7.0 7 0 0 7 7 7 4 Protein of unknown function (DUF2012) SpaA PF17802.1 EAX96889.1 - 1.9e-08 34.5 5.0 0.28 11.5 0.0 6.6 4 1 1 5 5 5 2 Prealbumin-like fold domain bMG3 PF11974.8 EAX96889.1 - 2.2e-05 24.4 0.4 0.11 12.5 0.0 5.0 6 0 0 6 6 6 1 Bacterial alpha-2-macroglobulin MG3 domain Big_6 PF17936.1 EAX96889.1 - 0.00042 20.5 14.4 5.6 7.3 0.4 6.2 5 1 1 6 6 6 2 Bacterial Ig domain Y_Y_Y PF07495.13 EAX96889.1 - 0.00089 19.2 0.1 4.7 7.2 0.0 4.1 4 0 0 4 4 4 2 Y_Y_Y domain fn3_3 PF14686.6 EAX96889.1 - 0.002 17.9 3.0 7.3 6.4 0.1 5.3 6 0 0 6 6 6 1 Polysaccharide lyase family 4, domain II MG4 PF17789.1 EAX96889.1 - 0.031 14.4 0.1 1.5 9.1 0.0 3.9 3 0 0 3 3 3 0 Macroglobulin domain MG4 fn3_6 PF17766.1 EAX96889.1 - 0.19 11.9 4.9 20 5.5 0.0 4.4 3 1 2 5 5 5 0 Fibronectin type-III domain LRR_5 PF13306.6 EAX96890.1 - 1.5e-116 383.8 79.0 2.3e-23 82.6 5.7 7.5 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96890.1 - 9.4e-25 86.2 3.9 0.0014 18.4 0.1 10.3 8 2 3 12 12 12 8 Leucine rich repeat LRR_4 PF12799.7 EAX96890.1 - 1.3e-05 25.4 11.3 12 6.4 0.3 9.1 8 1 2 10 10 10 2 Leucine Rich repeats (2 copies) Tetraspanin PF00335.20 EAX96891.1 - 5.2e-05 23.1 3.5 8.9e-05 22.3 3.5 1.4 1 1 0 1 1 1 1 Tetraspanin family Ldh_1_C PF02866.18 EAX96892.1 - 2.1e-21 76.6 0.0 2.3e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain HycA_repressor PF11046.8 EAX96892.1 - 0.023 14.9 0.2 0.039 14.2 0.2 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons LRR_5 PF13306.6 EAX96893.1 - 3.5e-102 337.4 84.6 9.9e-21 74.0 6.0 5.8 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96893.1 - 2.5e-08 33.5 16.7 0.23 11.2 0.5 10.4 9 3 2 11 11 11 3 Leucine rich repeat LRR_5 PF13306.6 EAX96894.1 - 2.5e-61 205.3 70.5 2.7e-22 79.1 12.8 3.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96894.1 - 9.7e-05 22.1 0.3 1.4 8.8 0.0 5.8 7 1 2 9 9 9 2 Leucine rich repeat GPS PF01825.21 EAX96894.1 - 9.2 6.9 9.8 10 6.7 0.1 4.6 5 1 1 6 6 6 0 GPCR proteolysis site, GPS, motif HAD_2 PF13419.6 EAX96895.1 - 5.7e-24 85.2 0.0 7.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX96895.1 - 1.8e-16 61.1 0.0 1.2e-13 51.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAX96895.1 - 7.3e-05 22.8 0.1 0.0059 16.7 0.1 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX96895.1 - 0.00018 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 EAX96895.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase DUF1574 PF07611.11 EAX96895.1 - 0.034 13.5 0.2 0.052 12.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) HAD PF12710.7 EAX96895.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cellulase PF00150.18 EAX96895.1 - 0.063 12.7 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Ytca PF17090.5 EAX96895.1 - 0.096 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family TTL PF03133.15 EAX96896.1 - 3.2e-55 187.3 0.2 1.1e-54 185.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX96896.1 - 8.3e-09 35.1 0.0 0.0079 15.5 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX96896.1 - 6e-06 25.7 0.0 0.0092 15.3 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX96896.1 - 7.5e-05 22.8 0.0 0.0077 16.3 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain DUF3824 PF12868.7 EAX96896.1 - 1.1 10.0 10.5 2 9.1 10.5 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PSP PF04046.16 EAX96897.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX96898.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX96899.1 - 0.022 15.2 0.6 0.045 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX96900.1 - 8e-51 170.0 34.5 1e-34 118.4 16.3 5.1 3 2 1 4 4 4 3 Phage tail repeat like DUF4116 PF13475.6 EAX96900.1 - 0.024 14.3 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX96901.1 - 3.9e-134 445.6 13.6 1.1e-133 444.1 13.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX96901.1 - 0.039 14.4 0.5 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fez1 PF06818.15 EAX96901.1 - 0.052 14.0 2.1 0.09 13.2 0.3 2.0 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX96901.1 - 0.28 11.7 9.1 0.77 10.3 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX96901.1 - 0.31 11.6 3.6 0.26 11.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DENN PF02141.21 EAX96902.1 - 2.4e-18 66.7 0.9 2.4e-18 66.7 0.9 2.0 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EAX96902.1 - 0.0072 17.0 0.0 0.02 15.6 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Ribosomal_L5e PF17144.4 EAX96904.1 - 0.071 13.1 1.9 0.091 12.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Cpn60_TCP1 PF00118.24 EAX96905.1 - 9.1e-158 525.9 1.9 1e-157 525.7 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chlorosome_CsmC PF11098.8 EAX96905.1 - 0.14 12.1 3.4 0.22 11.5 0.1 2.7 3 0 0 3 3 3 0 Chlorosome envelope protein C Chordopox_RPO7 PF05864.12 EAX96905.1 - 0.2 11.9 0.8 0.49 10.7 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DHHC PF01529.20 EAX96906.1 - 3.2e-20 72.6 1.7 3.2e-20 72.6 1.7 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 EAX96906.1 - 0.16 11.9 5.4 0.12 12.3 1.4 2.3 2 0 0 2 2 2 0 PIG-P HemY_N PF07219.13 EAX96906.1 - 1.7 8.8 4.3 13 6.0 0.1 2.5 2 1 0 2 2 2 0 HemY protein N-terminus Sel1 PF08238.12 EAX96907.1 - 0.00056 20.5 2.3 0.13 12.9 0.0 3.2 3 0 0 3 3 3 2 Sel1 repeat TPR_19 PF14559.6 EAX96907.1 - 0.0035 17.8 3.3 0.029 14.9 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX96907.1 - 0.026 14.8 1.2 2.7 8.3 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EAX96907.1 - 0.21 11.9 1.2 4.2 7.8 0.6 3.1 1 1 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.22 EAX96908.1 - 2.4e-51 173.6 0.0 2.7e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX96908.1 - 9.6e-23 80.7 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX96908.1 - 1e-05 25.1 0.0 1.4e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX96908.1 - 0.0012 18.4 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain BTRD1 PF17660.1 EAX96908.1 - 0.079 12.8 0.1 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Gtr1_RagA PF04670.12 EAX96908.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region LRR_5 PF13306.6 EAX96909.1 - 1e-104 345.6 72.1 7.6e-27 93.8 7.5 7.1 4 1 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96909.1 - 1.4e-26 92.0 10.5 0.00011 21.9 0.2 10.4 6 3 5 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 EAX96909.1 - 2.5e-06 27.7 13.1 0.12 12.8 0.2 7.9 6 1 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX96910.1 - 1.4e-30 105.9 15.9 3.5e-20 72.2 3.8 2.5 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX96911.1 - 1.8e-54 183.1 40.7 2.5e-25 88.9 11.6 3.2 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96911.1 - 4.5e-20 71.2 0.0 4.9e-06 26.2 0.0 5.5 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EAX96911.1 - 4.9e-08 33.1 7.8 0.085 13.3 0.1 5.8 4 3 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX96912.1 - 2.2e-100 331.6 79.8 1.7e-30 105.6 7.6 6.5 3 1 1 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96912.1 - 7.2e-24 83.3 8.7 1.2e-05 25.0 0.0 10.3 6 3 5 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 EAX96912.1 - 6.3e-06 26.4 19.9 0.19 12.2 0.1 8.6 7 3 2 10 10 10 3 Leucine Rich repeats (2 copies) ATP-synt_J PF04911.12 EAX96912.1 - 0.14 11.7 0.0 0.5 10.0 0.1 1.9 2 0 0 2 2 2 0 ATP synthase j chain Pkinase PF00069.25 EAX96913.1 - 2e-65 220.8 0.0 2.9e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96913.1 - 3.4e-29 101.9 0.0 4.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX96913.1 - 0.00086 18.7 0.0 0.0033 16.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EAX96913.1 - 0.084 12.5 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 EAX96914.1 - 0.013 16.0 0.1 0.042 14.5 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96914.1 - 0.047 14.3 0.0 0.7 10.5 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) TPR_8 PF13181.6 EAX96915.1 - 0.23 11.8 1.1 1.1 9.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat BUD22 PF09073.10 EAX96916.1 - 2 7.7 13.8 2.5 7.3 13.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EAX96917.1 - 0.012 14.9 0.5 0.018 14.3 0.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4838 PF16126.5 EAX96921.1 - 6e-81 271.7 1.7 1.2e-80 270.7 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Syndecan PF01034.20 EAX96921.1 - 0.087 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain ETRAMP PF09716.10 EAX96921.1 - 0.098 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.6 EAX96921.1 - 1.4 8.8 4.7 0.22 11.4 0.5 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF3492 PF11997.8 EAX96922.1 - 0.14 11.9 0.5 1 9.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) B56 PF01603.20 EAX96923.1 - 5.6e-60 203.5 10.3 8e-60 203.0 10.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RRM_1 PF00076.22 EAX96925.1 - 3.1e-07 30.1 0.0 8.1e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX96925.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif PseudoU_synth_1 PF01416.20 EAX96926.1 - 1.4e-11 44.8 0.0 6e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase TMEM154 PF15102.6 EAX96927.1 - 0.017 15.1 1.9 0.028 14.3 1.9 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3432 PF11914.8 EAX96928.1 - 0.00071 19.8 5.4 0.0016 18.6 5.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) DUF3827 PF12877.7 EAX96928.1 - 0.016 13.6 0.0 0.026 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Phage_holin_2_1 PF04971.12 EAX96928.1 - 0.029 14.3 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S Orf78 PF06024.12 EAX96928.1 - 0.078 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Cation_ATPase_C PF00689.21 EAX96929.1 - 0.056 13.1 3.6 0.058 13.1 0.9 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus HNH_2 PF13391.6 EAX96929.1 - 0.26 11.5 11.6 1.3e+04 -3.6 11.5 5.1 1 1 0 1 1 1 0 HNH endonuclease DUF1310 PF07006.11 EAX96930.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) RRM_1 PF00076.22 EAX96931.1 - 1.7e-07 30.9 0.2 2.2e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EAX96932.1 - 0.0019 17.9 0.0 0.0067 16.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M16C_assoc PF08367.11 EAX96934.1 - 4.7e-29 101.3 3.0 7.6e-29 100.6 3.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAX96934.1 - 1.4e-22 80.6 0.2 1.3e-20 74.1 0.0 3.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAX96934.1 - 3.8e-09 36.7 0.1 3.8e-09 36.7 0.1 3.1 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_S49 PF01343.18 EAX96934.1 - 0.13 12.2 0.2 0.63 10.0 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 CHIP_TPR_N PF18391.1 EAX96934.1 - 8.6 7.2 9.5 9.8 7.0 5.0 3.4 3 1 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain TMEM154 PF15102.6 EAX96935.1 - 5.6e-05 23.1 4.0 5.6e-05 23.1 4.0 2.4 2 1 1 3 3 3 1 TMEM154 protein family Herpes_BLLF1 PF05109.13 EAX96935.1 - 0.00031 18.9 17.8 0.00033 18.8 17.8 1.2 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) DUF5305 PF17231.2 EAX96935.1 - 0.00057 19.3 1.6 0.00082 18.8 1.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) PIRT PF15099.6 EAX96935.1 - 0.0037 16.9 1.0 0.0068 16.0 1.0 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Ion_trans PF00520.31 EAX96935.1 - 0.024 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein Peptidase_M56 PF05569.11 EAX96935.1 - 0.031 13.5 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 PRIMA1 PF16101.5 EAX96935.1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.5 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 MAP65_ASE1 PF03999.12 EAX96935.1 - 0.48 9.1 8.3 0.5 9.0 8.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) AKAP2_C PF15304.6 EAX96935.1 - 0.58 9.4 6.9 0.82 8.9 6.9 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus SOG2 PF10428.9 EAX96935.1 - 1 8.5 15.7 1.2 8.2 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_129 PF11308.8 EAX96936.1 - 9.8e-30 103.8 6.8 3.4e-27 95.5 6.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GH129 N2227 PF07942.12 EAX96936.1 - 0.028 13.6 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 N2227-like protein F5_F8_type_C PF00754.25 EAX96938.1 - 2e-06 28.0 0.0 9.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain DUF4625 PF15418.6 EAX96940.1 - 2.5e-05 24.5 12.3 0.22 11.8 0.2 6.7 3 1 1 5 5 5 2 Domain of unknown function (DUF4625) Big_7 PF17957.1 EAX96940.1 - 0.4 11.5 24.4 3 8.7 2.4 6.4 6 0 0 6 6 6 0 Bacterial Ig domain UQ_con PF00179.26 EAX96941.1 - 1.9e-22 79.4 0.9 2.1e-21 76.0 0.2 2.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme VWA PF00092.28 EAX96941.1 - 1.1e-13 51.8 2.3 1.1e-13 51.8 2.3 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAX96941.1 - 6.5e-12 46.0 0.2 4.7e-10 40.1 0.1 3.2 3 0 0 3 3 3 1 von Willebrand factor type A domain Prefoldin PF02996.17 EAX96941.1 - 0.011 15.6 0.9 0.041 13.8 0.9 2.0 1 0 0 1 1 1 0 Prefoldin subunit RasGAP_C PF03836.15 EAX96941.1 - 0.012 15.7 0.1 0.039 14.1 0.1 1.9 1 0 0 1 1 1 0 RasGAP C-terminus GvpK PF05121.12 EAX96941.1 - 0.067 13.2 0.7 0.43 10.6 0.1 2.5 3 0 0 3 3 3 0 Gas vesicle protein K Metallophos PF00149.28 EAX96942.1 - 6.5e-12 46.4 4.7 7.6e-12 46.2 3.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase GYD PF08734.11 EAX96942.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 GYD domain Myb_DNA-binding PF00249.31 EAX96943.1 - 6.7e-31 106.2 1.5 4.3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96943.1 - 8.8e-25 86.7 2.8 3.6e-13 49.6 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX96943.1 - 0.0004 20.5 0.1 0.024 14.8 0.0 2.5 1 1 1 2 2 2 1 Rap1 Myb domain SLIDE PF09111.10 EAX96943.1 - 0.0037 17.3 0.2 3.3 7.8 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX96943.1 - 0.01 15.7 3.5 0.055 13.4 1.5 2.9 1 1 1 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX96943.1 - 0.014 15.6 0.1 0.014 15.6 0.1 1.9 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 EcpB_C PF18649.1 EAX96943.1 - 0.089 12.8 1.3 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 EcpB C-terminal domain Myb_DNA-bind_5 PF13873.6 EAX96943.1 - 1.4 9.0 10.4 7.1 6.8 0.2 4.2 2 2 2 4 4 4 0 Myb/SANT-like DNA-binding domain ZapD PF07072.11 EAX96944.1 - 0.015 15.1 0.7 5.4 6.7 0.0 2.7 1 1 2 3 3 3 0 Cell division protein SPX PF03105.19 EAX96944.1 - 0.2 11.5 3.6 0.31 10.9 3.6 1.2 1 0 0 1 1 1 0 SPX domain Pep1_7 PF17232.2 EAX96944.1 - 0.25 11.8 5.6 14 6.2 0.1 3.4 1 1 1 3 3 3 0 Elicitor peptide 1-7 ChiC PF06483.11 EAX96944.1 - 0.3 11.0 4.0 2.6 7.9 0.1 2.7 2 1 1 3 3 3 0 Chitinase C GET2 PF08690.10 EAX96944.1 - 0.51 10.0 7.3 3.9 7.1 0.7 2.1 1 1 1 2 2 2 0 GET complex subunit GET2 Clr2 PF10383.9 EAX96944.1 - 0.82 10.4 2.9 12 6.7 0.4 2.2 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 DUF4587 PF15248.6 EAX96944.1 - 2.3 9.1 5.3 36 5.3 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4587) Lipid_DES PF08557.10 EAX96945.1 - 1.1 8.8 4.3 0.42 10.2 1.0 2.0 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) DUF1493 PF07377.12 EAX96946.1 - 0.034 14.6 0.5 0.071 13.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX96947.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX96948.1 - 0.07 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP PhosphMutase PF10143.9 EAX96949.1 - 8.8e-49 165.6 0.0 2e-48 164.5 0.0 1.6 2 0 0 2 2 2 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 EAX96949.1 - 5.3e-30 104.6 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Fibritin_C PF07921.12 EAX96949.1 - 0.023 14.8 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Fibritin C-terminal region Alk_phosphatase PF00245.20 EAX96949.1 - 0.024 13.6 0.5 0.039 12.9 0.5 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Phosphodiest PF01663.22 EAX96949.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Redoxin PF08534.10 EAX96949.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin SAS-6_N PF16531.5 EAX96950.1 - 0.018 15.6 1.4 0.056 14.0 0.1 2.6 2 0 0 2 2 2 0 Centriolar protein SAS N-terminal LRR_5 PF13306.6 EAX96951.1 - 1.9e-144 474.0 105.2 4.8e-36 123.5 17.4 5.2 2 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96951.1 - 2.2e-20 72.1 3.6 0.012 15.3 0.0 8.5 5 3 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EAX96951.1 - 0.0039 17.6 15.4 8.2 7.0 1.5 7.9 5 3 3 8 8 8 1 Leucine Rich repeats (2 copies) HCBP_related PF06594.11 EAX96951.1 - 6.4 6.8 8.1 18 5.3 0.1 3.9 3 1 1 4 4 4 0 Haemolysin-type calcium binding protein related domain MULE PF10551.9 EAX96953.1 - 1e-07 32.3 0.2 1.7e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX96953.1 - 0.00085 19.4 1.1 0.0024 17.9 1.1 1.7 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma LRR_5 PF13306.6 EAX96954.1 - 1.7e-89 296.3 63.1 9.3e-36 122.6 16.5 5.2 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96954.1 - 4.7e-15 55.1 6.0 0.012 15.4 0.0 7.8 4 2 5 9 9 9 7 Leucine rich repeat LRR_5 PF13306.6 EAX96955.1 - 9.2e-146 478.3 110.8 8.5e-35 119.5 17.9 6.6 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96955.1 - 2.2e-18 65.8 6.8 0.016 14.9 0.0 8.9 5 2 5 10 10 10 8 Leucine rich repeat LRR_5 PF13306.6 EAX96956.1 - 6.7e-102 336.5 73.9 1e-35 122.5 18.9 5.6 2 2 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX96956.1 - 5e-17 61.4 4.2 0.016 15.0 0.0 8.0 7 2 1 8 8 8 5 Leucine rich repeat TAFA PF12020.8 EAX96957.1 - 0.05 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 TAFA family PPR_1 PF12854.7 EAX96957.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 PPR repeat UCH PF00443.29 EAX96958.1 - 1.3e-36 126.4 0.0 2.7e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX96958.1 - 2.4e-11 44.1 0.1 2.4e-11 44.1 0.1 2.5 3 1 1 4 4 4 1 DUSP domain UCH_1 PF13423.6 EAX96958.1 - 9.7e-07 28.7 5.4 0.00044 19.9 1.3 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Tau95_N PF17682.1 EAX96958.1 - 0.53 10.5 5.7 7.5 6.8 5.7 2.3 1 1 0 1 1 1 0 Tau95 Triple barrel domain DUF2812 PF11193.8 EAX96959.1 - 0.005 17.0 0.4 0.0084 16.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2812) PhetRS_B1 PF18262.1 EAX96959.1 - 0.15 12.3 1.6 1 9.6 1.4 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Bap31_Bap29_C PF18035.1 EAX96960.1 - 0.02 14.9 4.0 0.02 14.9 4.0 4.3 5 1 0 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain Guanylin PF02058.15 EAX96960.1 - 1.1 9.7 9.5 0.16 12.4 3.0 2.7 2 1 0 2 2 2 0 Guanylin precursor Ank_4 PF13637.6 EAX96962.1 - 2e-43 146.2 5.6 4.7e-13 49.4 0.1 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX96962.1 - 8e-39 130.4 3.2 1.2e-07 31.9 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 EAX96962.1 - 1e-33 115.8 12.9 1.9e-13 50.8 0.8 4.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX96962.1 - 8.3e-30 99.5 6.8 5.5e-06 26.3 0.1 6.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX96962.1 - 3.4e-29 100.5 1.7 1.2e-08 35.1 0.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96962.1 - 1.5e-22 79.3 8.1 1.5e-22 79.3 8.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX96962.1 - 9.1e-05 22.5 4.0 1.6 9.0 0.1 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF3718) SAB PF04382.13 EAX96962.1 - 8.1 6.6 6.4 1.8e+02 2.3 0.1 4.0 4 0 0 4 4 4 0 SAB domain WD40 PF00400.32 EAX96963.1 - 1.2e-16 60.7 0.1 2.1e-06 28.4 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX96963.1 - 7.8e-10 38.9 0.0 0.00098 19.4 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAX96963.1 - 0.003 17.5 2.3 0.18 11.8 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Pectate_lyase22 PF14583.6 EAX96963.1 - 0.0062 15.2 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 Oligogalacturonate lyase Ge1_WD40 PF16529.5 EAX96963.1 - 0.051 12.5 0.0 0.4 9.6 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FapA PF03961.13 EAX96964.1 - 0.004 15.8 5.8 0.0042 15.7 5.8 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A UPF0242 PF06785.11 EAX96964.1 - 0.0048 17.0 7.2 0.0049 17.0 7.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 EAX96964.1 - 0.0085 16.5 6.0 0.011 16.1 6.0 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 EAX96964.1 - 0.014 15.6 10.3 0.45 10.8 10.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NleF_casp_inhib PF16809.5 EAX96964.1 - 0.02 14.8 5.5 0.021 14.8 1.0 2.0 1 1 1 2 2 2 0 NleF caspase inhibitor AAA_13 PF13166.6 EAX96964.1 - 0.021 13.5 6.2 0.024 13.3 6.2 1.0 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 EAX96964.1 - 0.021 14.6 7.5 0.032 14.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Med9 PF07544.13 EAX96964.1 - 0.024 14.7 7.9 1.3 9.2 2.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CortBP2 PF09727.9 EAX96964.1 - 0.035 14.0 11.8 0.045 13.6 11.7 1.2 1 1 0 1 1 1 0 Cortactin-binding protein-2 PHM7_cyt PF14703.6 EAX96964.1 - 0.039 14.2 4.8 0.13 12.4 5.0 1.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF1917 PF08939.10 EAX96964.1 - 0.039 13.8 2.5 0.05 13.5 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) OmpH PF03938.14 EAX96964.1 - 0.052 13.9 11.5 0.059 13.7 11.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_11 PF13086.6 EAX96964.1 - 0.053 13.3 5.1 0.06 13.1 5.1 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EAX96964.1 - 0.064 13.3 8.9 0.1 12.6 8.8 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ETRAMP PF09716.10 EAX96964.1 - 0.073 13.1 3.1 0.2 11.8 3.1 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMPIT PF07851.13 EAX96964.1 - 0.13 11.5 3.0 0.15 11.3 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.6 EAX96964.1 - 0.26 11.7 8.7 3.1 8.3 1.7 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF1216 PF06746.11 EAX96964.1 - 0.33 11.0 6.1 0.42 10.6 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) Metal_resist PF13801.6 EAX96964.1 - 0.35 11.1 1.6 0.61 10.3 1.6 1.4 1 1 0 1 1 1 0 Heavy-metal resistance Ureide_permease PF07168.11 EAX96964.1 - 0.37 9.5 0.4 0.43 9.3 0.4 1.1 1 0 0 1 1 1 0 Ureide permease FliT PF05400.13 EAX96964.1 - 0.39 11.6 7.5 0.79 10.6 1.3 2.3 1 1 1 2 2 2 0 Flagellar protein FliT DUF3987 PF13148.6 EAX96964.1 - 0.48 9.4 3.3 0.54 9.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Prefoldin_2 PF01920.20 EAX96964.1 - 0.54 10.2 14.8 0.22 11.5 7.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit CemA PF03040.14 EAX96964.1 - 0.55 10.1 3.3 0.68 9.8 3.3 1.2 1 0 0 1 1 1 0 CemA family APG6_N PF17675.1 EAX96964.1 - 0.64 10.6 12.6 2.7 8.5 12.6 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Goodbye PF17109.5 EAX96964.1 - 0.66 10.4 5.5 1.4 9.4 0.4 2.2 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Spc24 PF08286.11 EAX96964.1 - 0.79 10.0 8.0 4.1 7.7 8.0 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CpxA_peri PF16527.5 EAX96964.1 - 0.96 9.8 6.0 1.5 9.2 5.8 1.5 1 1 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain DUF1664 PF07889.12 EAX96964.1 - 1.1 9.3 5.8 2 8.5 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EAX96964.1 - 1.5 9.2 9.1 2.6 8.5 3.3 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EAX96964.1 - 1.7 7.7 10.1 4 6.4 10.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MtrG PF04210.13 EAX96964.1 - 3.5 7.5 5.5 8 6.4 0.2 2.6 1 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Med21 PF11221.8 EAX96964.1 - 6.1 7.1 12.4 0.79 10.0 4.9 2.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Bromodomain PF00439.25 EAX96965.1 - 1.4e-24 86.0 0.0 3.1e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX96965.1 - 0.0075 16.4 0.1 0.0075 16.4 0.1 2.8 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation CENP-T_C PF15511.6 EAX96966.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX96966.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX96966.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX96966.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX96966.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX96966.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX96966.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX96966.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EAX96967.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX96967.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX96967.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX96967.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein LisH PF08513.11 EAX96968.1 - 1.1e-07 31.6 1.7 4.4e-05 23.3 0.2 2.6 2 0 0 2 2 2 2 LisH HEAT_2 PF13646.6 EAX96968.1 - 6.5e-07 29.6 0.9 0.026 14.9 0.1 3.5 3 1 0 3 3 3 2 HEAT repeats OmpH PF03938.14 EAX96968.1 - 0.00047 20.5 3.8 0.014 15.7 2.7 2.6 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) HEAT PF02985.22 EAX96968.1 - 0.0006 19.9 3.9 0.79 10.2 0.0 5.3 5 0 0 5 5 3 1 HEAT repeat RTP1_C1 PF10363.9 EAX96968.1 - 0.0013 18.9 0.8 0.074 13.2 0.0 3.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DASH_Ask1 PF08655.10 EAX96968.1 - 0.0067 16.3 0.0 2.7 7.9 0.0 3.7 3 0 0 3 3 3 1 DASH complex subunit Ask1 HEAT_EZ PF13513.6 EAX96968.1 - 0.0082 16.6 1.0 4.8 7.8 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Dopey_N PF04118.14 EAX96968.1 - 0.01 15.0 0.0 0.17 11.0 0.0 2.8 1 1 2 3 3 3 0 Dopey, N-terminal CSN5_C PF18323.1 EAX96968.1 - 0.033 15.1 0.3 0.29 12.1 0.1 2.5 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Spc24 PF08286.11 EAX96968.1 - 0.088 13.1 3.9 2.2 8.5 1.7 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cast PF10174.9 EAX96968.1 - 0.14 10.4 10.1 0.44 8.7 0.2 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF4407 PF14362.6 EAX96968.1 - 0.26 10.6 3.2 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CC2-LZ PF16516.5 EAX96968.1 - 0.77 10.2 12.9 0.36 11.2 6.4 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KxDL PF10241.9 EAX96968.1 - 0.91 9.8 6.2 0.41 10.9 1.2 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 EAX96968.1 - 0.98 9.6 14.7 0.96 9.6 0.5 2.8 3 0 0 3 3 3 0 Tropomyosin like Prefoldin PF02996.17 EAX96968.1 - 2.3 8.1 12.6 2.4 8.1 0.5 2.8 2 0 0 2 2 2 0 Prefoldin subunit DUF2570 PF10828.8 EAX96968.1 - 2.6 7.9 7.5 1.4 8.8 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) CENP-F_leu_zip PF10473.9 EAX96968.1 - 4 7.5 12.7 1.4 8.9 5.4 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EAX96968.1 - 5.7 7.0 6.1 2.8 8.0 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) S1-P1_nuclease PF02265.16 EAX96969.1 - 6.8e-43 147.3 0.1 7.8e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Ribosomal_S3Ae PF01015.18 EAX96970.1 - 2.2e-56 190.6 3.9 2.7e-56 190.3 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Fe-S_assembly PF04384.13 EAX96971.1 - 0.023 15.3 0.1 3.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly PG_binding_2 PF08823.11 EAX96972.1 - 0.019 15.3 0.1 0.31 11.4 0.1 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Dimer_Tnp_hAT PF05699.14 EAX96972.1 - 0.31 10.8 1.4 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DUF4107 PF13389.6 EAX96973.1 - 3.6e-22 79.3 1.2 4e-22 79.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4795 PF16043.5 EAX96974.1 - 9.7e-05 22.1 32.1 1 8.9 6.1 5.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) AlkA_N PF06029.11 EAX96974.1 - 0.076 13.3 0.0 22 5.3 0.0 2.4 2 0 0 2 2 2 0 AlkA N-terminal domain DUF2018 PF09442.10 EAX96974.1 - 0.16 12.9 14.3 21 6.2 0.7 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2018) SEP PF08059.13 EAX96974.1 - 0.68 10.6 10.1 2.9 8.5 0.3 3.6 3 0 0 3 3 3 0 SEP domain Peptidase_U57 PF05582.12 EAX96974.1 - 1.9 7.6 10.9 4.9 6.3 2.7 2.3 1 1 1 2 2 2 0 YabG peptidase U57 Peptidase_M24_C PF16188.5 EAX96974.1 - 4.3 7.5 6.2 50 4.1 0.4 3.4 2 1 0 2 2 2 0 C-terminal region of peptidase_M24 Arm_3 PF16186.5 EAX96975.1 - 0.0041 16.6 1.5 0.049 13.2 0.1 3.0 2 0 0 2 2 2 1 Atypical Arm repeat DUF3631 PF12307.8 EAX96975.1 - 0.11 12.7 1.5 3.5 7.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3631) Methyltransf_21 PF05050.12 EAX96976.1 - 5.4e-11 42.8 0.1 8.3e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain HyaE PF07449.11 EAX96976.1 - 0.001 19.0 0.0 0.76 9.8 0.0 2.9 2 1 1 3 3 3 2 Hydrogenase-1 expression protein HyaE Met_10 PF02475.16 EAX96976.1 - 0.035 13.8 0.1 0.083 12.6 0.2 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Pre-SET PF05033.16 EAX96976.1 - 0.038 14.6 2.6 0.096 13.3 2.6 1.6 1 0 0 1 1 1 0 Pre-SET motif Methyltransf_25 PF13649.6 EAX96976.1 - 0.096 13.4 0.0 0.48 11.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain DUF4407 PF14362.6 EAX96977.1 - 0.00011 21.6 49.4 0.00028 20.3 14.8 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 EAX96977.1 - 0.021 14.9 5.6 0.021 14.9 5.6 7.0 3 3 3 7 7 7 0 TolA binding protein trimerisation ArfA PF03889.13 EAX96977.1 - 0.076 12.5 0.7 0.19 11.2 0.7 1.7 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A KASH_CCD PF14662.6 EAX96977.1 - 0.22 11.3 96.6 0.053 13.3 15.8 6.6 2 1 6 8 8 8 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 EAX96977.1 - 0.5 10.8 76.9 0.054 13.9 24.8 4.5 2 1 3 5 5 5 0 Fez1 Spc7 PF08317.11 EAX96977.1 - 0.61 8.9 83.5 0.025 13.5 22.8 3.7 1 1 1 3 3 3 0 Spc7 kinetochore protein DASH_Hsk3 PF08227.11 EAX96977.1 - 1.4 9.4 17.2 0.061 13.7 2.6 4.4 4 1 0 4 4 4 0 DASH complex subunit Hsk3 like ATG16 PF08614.11 EAX96977.1 - 7.1 6.8 73.1 0.68 10.1 27.1 5.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Sec7 PF01369.20 EAX96978.1 - 1.9e-23 83.1 1.6 1.9e-23 83.1 1.6 3.1 3 1 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 EAX96978.1 - 1e-07 31.7 3.0 9.5e-07 28.6 0.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) CLTH PF10607.9 EAX96978.1 - 0.092 12.6 3.3 0.4 10.6 0.1 2.9 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Choline_transpo PF04515.12 EAX96979.1 - 4.8e-37 127.9 43.9 4.8e-37 127.9 43.9 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 EAX96980.1 - 6.6e-33 114.3 42.2 6.6e-33 114.3 42.2 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Borrelia_orfD PF02999.14 EAX96981.1 - 0.13 12.6 4.3 31 4.9 0.0 3.9 3 0 0 3 3 3 0 Borrelia orf-D family AAA_6 PF12774.7 EAX96982.1 - 8.1e-159 527.9 0.0 4.2e-157 522.2 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EAX96982.1 - 4.1e-115 385.1 11.0 4.1e-115 385.1 11.0 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EAX96982.1 - 3.7e-99 331.8 0.1 3.7e-99 331.8 0.1 3.7 5 0 0 5 5 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EAX96982.1 - 2e-92 309.2 0.4 9.9e-92 306.9 0.4 2.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EAX96982.1 - 1.6e-72 243.2 4.2 1.6e-72 243.2 4.2 3.9 5 1 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 EAX96982.1 - 1.7e-65 220.0 0.0 1.9e-59 200.2 0.0 4.6 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EAX96982.1 - 1.5e-54 184.3 0.0 4.4e-54 182.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAX96982.1 - 2e-42 144.0 1.9 6.2e-41 139.2 0.0 4.5 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EAX96982.1 - 5.7e-36 124.2 10.3 5.7e-36 124.2 10.3 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EAX96982.1 - 1.1e-28 99.9 0.3 6e-28 97.5 0.3 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EAX96982.1 - 1.2e-20 73.9 0.0 0.00015 21.8 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EAX96982.1 - 1.3e-20 73.5 0.1 7.9e-20 70.9 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EAX96982.1 - 3.3e-11 43.8 0.0 0.027 15.0 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 EAX96982.1 - 7.3e-07 29.7 0.4 0.055 13.9 0.0 4.8 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX96982.1 - 1e-06 29.2 6.0 0.36 11.2 0.0 6.5 6 1 1 7 7 6 1 AAA ATPase domain RNA_helicase PF00910.22 EAX96982.1 - 1.2e-06 28.9 0.6 6.1 7.3 0.0 5.4 6 0 0 6 6 4 1 RNA helicase AAA_33 PF13671.6 EAX96982.1 - 4.7e-06 26.8 0.0 6 7.0 0.0 5.5 5 0 0 5 5 5 1 AAA domain AAA_22 PF13401.6 EAX96982.1 - 1.8e-05 25.0 2.3 5.3 7.3 0.0 6.0 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.27 EAX96982.1 - 2.8e-05 24.7 0.5 11 6.6 0.0 4.8 4 0 0 4 4 3 0 ABC transporter AAA_30 PF13604.6 EAX96982.1 - 0.00062 19.5 1.5 8 6.1 0.2 4.2 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 EAX96982.1 - 0.0019 17.4 4.7 0.014 14.6 0.0 4.1 4 0 0 4 4 4 1 NB-ARC domain RsgA_GTPase PF03193.16 EAX96982.1 - 0.0029 17.5 4.9 1.9 8.4 0.0 4.8 4 0 0 4 4 4 1 RsgA GTPase Rad17 PF03215.15 EAX96982.1 - 0.0035 17.3 0.1 7.6 6.4 0.0 3.9 3 0 0 3 3 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EAX96982.1 - 0.01 15.2 0.3 3.4 7.0 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Peptidase_C10 PF01640.17 EAX96982.1 - 0.011 16.1 0.0 0.48 10.7 0.0 2.8 2 0 0 2 2 2 0 Peptidase C10 family AAA_28 PF13521.6 EAX96982.1 - 0.014 15.7 0.0 2.7 8.2 0.0 3.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAX96982.1 - 0.015 15.0 0.1 18 5.2 0.1 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EAX96982.1 - 0.11 12.8 6.3 0.94 9.8 0.0 4.1 5 0 0 5 5 3 0 AAA domain FUSC PF04632.12 EAX96982.1 - 5.8 5.3 14.4 0.16 10.4 4.3 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pox_EPC_I2-L1 PF12575.8 EAX96984.1 - 0.15 12.3 3.3 3.8 7.8 1.4 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 BT1 PF03092.16 EAX96985.1 - 0.051 11.8 0.0 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 BT1 family TMEM154 PF15102.6 EAX96985.1 - 0.062 13.2 0.7 0.071 13.0 0.7 1.2 1 0 0 1 1 1 0 TMEM154 protein family ATP-synt_B PF00430.18 EAX96985.1 - 0.19 11.8 0.7 0.26 11.4 0.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Pkinase_Tyr PF07714.17 EAX96986.1 - 7e-58 195.9 0.0 1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX96986.1 - 1.8e-55 188.2 0.0 3.4e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAX96986.1 - 0.00075 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX96986.1 - 0.0041 15.9 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX96986.1 - 0.014 15.0 0.1 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 EAX96986.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ssl1 PF04056.14 EAX96986.1 - 0.1 12.4 0.5 7 6.4 0.0 2.8 2 1 1 3 3 3 0 Ssl1-like Ank_2 PF12796.7 EAX96987.1 - 1.8e-57 191.8 36.0 3.2e-15 56.5 1.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX96987.1 - 1.1e-40 137.4 9.7 6.4e-13 48.9 0.2 7.9 5 2 4 9 9 9 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX96987.1 - 1.5e-37 127.3 6.1 1.5e-37 127.3 6.1 4.4 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX96987.1 - 2.5e-36 122.5 6.2 4.7e-08 33.1 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX96987.1 - 1.2e-31 105.2 13.5 2.1e-05 24.5 0.0 9.5 10 1 1 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 EAX96987.1 - 1.1e-25 89.3 6.4 2.6e-11 43.5 0.2 6.0 3 3 2 6 6 6 4 Ankyrin repeats (many copies) CdhD PF03599.16 EAX96987.1 - 0.02 13.6 0.2 0.47 9.1 0.0 2.3 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit CAP_GLY PF01302.25 EAX96988.1 - 3.3e-15 55.8 0.2 5.4e-15 55.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain KxDL PF10241.9 EAX96988.1 - 0.0071 16.6 10.4 0.017 15.4 1.9 3.3 2 0 0 2 2 2 1 Uncharacterized conserved protein AAA_5 PF07728.14 EAX96988.1 - 0.059 13.4 0.9 0.16 12.0 0.6 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Spore_III_AE PF09546.10 EAX96988.1 - 0.19 10.9 0.5 0.27 10.4 0.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Noelin-1 PF12308.8 EAX96988.1 - 1 9.4 5.1 0.87 9.6 0.9 2.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein BCDHK_Adom3 PF10436.9 EAX96988.1 - 7.4 6.4 12.0 0.043 13.6 1.7 2.5 3 1 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Amidase02_C PF12123.8 EAX96989.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX96990.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX96990.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Insulin_TMD PF17870.1 EAX96992.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Myb_DNA-binding PF00249.31 EAX96994.1 - 9.6e-26 89.7 0.5 9.1e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX96994.1 - 3.9e-24 84.7 0.9 1.1e-16 60.8 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EAX96994.1 - 0.0062 16.9 0.5 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX96994.1 - 0.042 13.7 0.1 1.7 8.6 0.0 2.2 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX96994.1 - 0.067 13.4 0.0 0.23 11.7 0.0 2.0 1 1 1 2 2 2 0 Rap1 Myb domain SLIDE PF09111.10 EAX96994.1 - 0.11 12.5 0.0 6.9 6.7 0.0 2.4 1 1 1 2 2 2 0 SLIDE Thioredoxin_6 PF13848.6 EAX96995.1 - 1.3e-07 31.7 5.3 0.00052 20.0 0.5 3.5 2 1 2 4 4 4 3 Thioredoxin-like domain Pkinase PF00069.25 EAX96996.1 - 8.5e-55 186.0 0.0 1.2e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX96996.1 - 4e-35 121.3 0.0 4.9e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX96996.1 - 8.6e-05 22.6 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX96996.1 - 0.00026 19.9 0.0 0.00092 18.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YukC PF10140.9 EAX96996.1 - 0.0043 15.9 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kinase-like PF14531.6 EAX96996.1 - 0.0071 15.7 0.0 0.26 10.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX96996.1 - 0.0073 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX96996.1 - 0.0074 15.3 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EAX96996.1 - 0.043 13.4 0.3 0.069 12.7 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_6 PF12774.7 EAX96997.1 - 1.1e-152 507.7 0.1 3.7e-151 502.7 0.0 2.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EAX96997.1 - 1.5e-112 377.1 2.9 1.5e-112 377.1 2.9 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EAX96997.1 - 1.5e-108 363.5 15.6 1.5e-108 363.5 15.6 4.9 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EAX96997.1 - 1e-98 329.8 4.9 1.6e-97 325.9 1.2 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EAX96997.1 - 5.3e-94 314.9 0.1 1.2e-92 310.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EAX96997.1 - 4.1e-74 248.4 4.8 4.1e-74 248.4 4.8 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EAX96997.1 - 4.6e-73 244.6 1.2 8.6e-68 227.4 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EAX96997.1 - 1.5e-52 177.8 0.0 4.5e-52 176.2 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAX96997.1 - 9.4e-41 138.6 0.1 3.6e-37 127.1 0.0 3.5 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EAX96997.1 - 1.8e-38 132.4 5.5 3.7e-38 131.4 5.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EAX96997.1 - 5.1e-28 97.8 0.0 6.3e-10 39.2 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EAX96997.1 - 6.3e-27 94.2 0.3 4.1e-26 91.6 0.3 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EAX96997.1 - 6.5e-21 74.4 0.8 2.7e-20 72.4 0.2 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 EAX96997.1 - 1.3e-10 41.8 0.2 0.08 13.4 0.0 5.6 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX96997.1 - 8.9e-09 35.7 3.5 0.0045 17.3 0.0 5.3 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 EAX96997.1 - 1.4e-05 24.9 0.3 2.7 7.7 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EAX96997.1 - 1.6e-05 25.4 3.6 23 5.3 0.0 6.1 5 1 1 6 6 6 0 AAA ATPase domain AAA_33 PF13671.6 EAX96997.1 - 0.0002 21.5 0.1 5.9 7.1 0.0 4.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EAX96997.1 - 0.00067 20.0 0.2 4.9 7.6 0.1 4.3 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 EAX96997.1 - 0.0026 16.9 0.2 0.0087 15.1 0.2 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 EAX96997.1 - 0.0036 17.8 1.8 7.2 7.2 0.0 4.2 4 0 0 4 4 2 0 AAA domain DUF853 PF05872.12 EAX96997.1 - 0.025 13.2 4.3 1.9 7.0 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 EAX96997.1 - 0.09 12.5 0.0 0.98 9.2 0.0 2.9 2 1 0 2 2 1 0 DEAD/DEAH box helicase CbiA PF01656.23 EAX96997.1 - 0.11 12.6 0.8 3.1 7.9 0.0 3.5 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 EAX96997.1 - 0.15 12.1 3.7 9.3 6.3 0.1 4.4 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EAX96997.1 - 0.18 11.5 2.2 5.1 6.9 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 EAX96997.1 - 0.63 9.6 8.9 0.78 9.3 0.8 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EAX96997.1 - 0.67 9.2 3.4 2.8 7.2 0.0 3.5 4 0 0 4 4 4 0 Zeta toxin ATP_bind_1 PF03029.17 EAX96997.1 - 1 9.1 3.7 27 4.4 0.2 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EAX96997.1 - 3.2 8.3 6.2 7.4 7.1 0.0 4.5 5 0 0 5 5 3 0 ABC transporter ResIII PF04851.15 EAX96997.1 - 8.6 6.3 13.2 1.1 9.3 0.1 4.4 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit Bromodomain PF00439.25 EAX96999.1 - 1.3e-14 54.0 0.2 3.6e-14 52.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain UPF0220 PF05255.11 EAX97000.1 - 0.011 15.3 1.0 0.011 15.3 1.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) BCL9 PF11502.8 EAX97000.1 - 0.26 11.1 0.4 0.55 10.1 0.4 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein COPI_C PF06957.11 EAX97000.1 - 0.73 8.5 4.0 1.1 7.9 4.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Gar1 PF04410.14 EAX97002.1 - 7.6e-14 51.8 0.0 9.3e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region VWA_N2 PF16164.5 EAX97004.1 - 0.024 14.8 0.4 0.97 9.6 0.0 2.2 2 0 0 2 2 2 0 VWA N-terminal zf-MIZ PF02891.20 EAX97005.1 - 1.4e-14 53.5 0.1 2.3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAX97005.1 - 0.00045 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit C2 PF00168.30 EAX97007.1 - 9.8e-190 616.8 31.2 1.7e-24 86.0 0.1 8.6 8 0 0 8 8 8 8 C2 domain P2_Phage_GpR PF06891.11 EAX97007.1 - 0.01 15.9 5.0 0.046 13.8 0.4 3.8 3 0 0 3 3 3 0 P2 phage tail completion protein R (GpR) PAS_9 PF13426.7 EAX97007.1 - 0.013 15.7 2.8 13 6.1 0.0 6.1 6 0 0 6 6 6 0 PAS domain DOCK-C2 PF14429.6 EAX97007.1 - 1.7 8.4 44.5 0.41 10.4 3.0 9.6 8 2 1 10 10 10 0 C2 domain in Dock180 and Zizimin proteins DUF4107 PF13389.6 EAX97008.1 - 5.1e-34 117.8 1.8 7.3e-34 117.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX97009.1 - 0.013 15.2 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX97010.1 - 2.8e-117 390.4 6.7 3.2e-117 390.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX97010.1 - 0.3 11.5 2.0 0.81 10.2 0.5 2.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX97011.1 - 6.2e-109 356.1 73.8 5.8e-33 112.7 14.9 5.2 2 2 3 5 5 5 4 Phage tail repeat like Thioredoxin_6 PF13848.6 EAX97012.1 - 3.2e-32 111.9 3.6 1e-29 103.8 3.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 EAX97012.1 - 1.9e-11 43.8 0.0 0.00034 20.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EAX97012.1 - 0.0012 18.2 0.3 0.024 14.0 0.1 2.7 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family TraF PF13728.6 EAX97012.1 - 0.058 13.2 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein Vps39_2 PF10367.9 EAX97013.1 - 6.2e-14 52.4 0.1 2.1e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Ank_2 PF12796.7 EAX97014.1 - 1.4e-126 413.3 64.4 3.7e-17 62.7 0.5 13.6 1 1 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97014.1 - 4.3e-122 397.1 52.8 2.9e-13 50.1 0.4 21.9 6 4 17 23 23 23 20 Ankyrin repeats (many copies) Ank PF00023.30 EAX97014.1 - 2.4e-116 375.6 50.3 1.2e-06 28.7 0.1 24.2 25 0 0 25 25 25 22 Ankyrin repeat Ank_3 PF13606.6 EAX97014.1 - 9.6e-102 320.5 55.4 3.5e-05 23.8 0.3 25.6 26 1 1 27 27 27 21 Ankyrin repeat Ank_5 PF13857.6 EAX97014.1 - 5.6e-95 310.2 43.8 4.6e-11 42.7 2.2 17.5 7 4 11 20 20 20 16 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97014.1 - 6.7e-36 122.1 51.8 1.6e-34 117.7 3.6 8.9 3 2 6 9 9 9 5 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX97014.1 - 0.0045 17.2 1.3 10 6.5 0.0 4.5 3 1 0 3 3 3 1 Pleckstrin homology domain Peptidase_M16 PF00675.20 EAX97014.1 - 0.022 14.7 5.9 5 7.1 0.0 5.6 6 0 0 6 6 6 0 Insulinase (Peptidase family M16) Ribosomal_S6 PF01250.17 EAX97014.1 - 0.022 15.0 1.4 12 6.2 0.0 5.2 5 1 0 5 5 5 0 Ribosomal protein S6 WRKY PF03106.15 EAX97016.1 - 0.016 15.4 3.6 0.04 14.2 1.1 2.6 1 1 1 2 2 2 0 WRKY DNA -binding domain Pkinase PF00069.25 EAX97017.1 - 5.5e-71 239.0 0.2 1.3e-70 237.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97017.1 - 7.3e-41 140.2 0.1 1.4e-40 139.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97017.1 - 5.6e-07 29.2 0.3 6.4e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 EAX97017.1 - 3e-06 27.0 0.2 8.4e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EAX97017.1 - 6.8e-05 22.0 0.4 0.00012 21.1 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EAX97017.1 - 8.5e-05 22.0 0.2 0.00024 20.5 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NAF PF03822.14 EAX97017.1 - 0.00088 19.4 0.1 0.002 18.2 0.1 1.6 1 0 0 1 1 1 1 NAF domain APH PF01636.23 EAX97017.1 - 0.024 14.5 0.3 0.057 13.3 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family KA1 PF02149.19 EAX97017.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 Histone_HNS PF00816.21 EAX97017.1 - 0.22 12.4 2.0 0.64 10.9 2.0 1.7 1 0 0 1 1 1 0 H-NS histone family Ank_2 PF12796.7 EAX97019.1 - 4.1e-68 226.0 43.8 6.6e-19 68.3 5.3 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97019.1 - 7.7e-54 179.4 11.1 1.6e-09 38.1 0.1 6.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX97019.1 - 1.1e-49 164.7 13.9 1.6e-07 31.5 0.1 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAX97019.1 - 7.1e-41 133.5 15.1 5.2e-06 26.4 0.0 8.1 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX97019.1 - 1.2e-35 121.1 3.0 1e-10 41.6 0.0 4.9 3 2 0 4 4 4 3 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAX97019.1 - 5.7e-07 29.7 0.0 7.2 7.0 0.0 5.5 1 1 4 5 5 5 1 N terminal of Calcineurin-like phosphoesterase DUF3447 PF11929.8 EAX97019.1 - 0.013 15.4 0.8 0.013 15.4 0.8 4.8 4 2 0 4 4 4 0 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX97019.1 - 0.02 15.0 3.3 6.4 7.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3718) DUF1413 PF07205.11 EAX97019.1 - 0.044 13.8 0.5 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF348 PF03990.14 EAX97019.1 - 2 8.2 6.4 1.5e+02 2.2 0.0 5.1 6 0 0 6 6 6 0 G5-linked-Ubiquitin-like domain Hit1_C PF18268.1 EAX97020.1 - 0.014 15.5 0.4 4.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Hit1 C-terminal PSP PF04046.16 EAX97021.1 - 0.055 13.3 0.5 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97022.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat CH PF00307.31 EAX97023.1 - 0.1 12.8 0.0 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain Thymidylate_kin PF02223.17 EAX97024.1 - 2e-47 161.3 0.0 2.3e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EAX97024.1 - 4.4e-06 27.0 0.0 5.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAX97024.1 - 0.0003 21.3 0.0 0.00044 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX97024.1 - 0.0045 17.3 0.2 0.14 12.5 0.1 2.4 1 1 2 3 3 3 1 AAA domain AAA_17 PF13207.6 EAX97024.1 - 0.013 16.0 0.1 0.13 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EAX97024.1 - 0.025 14.3 0.1 7.4 6.2 0.0 2.3 2 1 0 2 2 2 0 Cytidylate kinase dNK PF01712.19 EAX97024.1 - 0.063 13.1 0.0 2 8.2 0.0 2.4 1 1 0 1 1 1 0 Deoxynucleoside kinase ADK PF00406.22 EAX97024.1 - 0.11 12.6 0.1 0.76 9.9 0.0 2.2 2 1 0 2 2 2 0 Adenylate kinase SNARE PF05739.19 EAX97025.1 - 2.3e-11 43.5 0.2 8.5e-11 41.7 0.2 2.0 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EAX97025.1 - 0.0002 21.2 6.8 0.00044 20.1 6.7 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 HTH_34 PF13601.6 EAX97025.1 - 0.032 14.4 0.3 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain ETRAMP PF09716.10 EAX97025.1 - 0.042 13.9 0.1 0.095 12.8 0.1 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 EAX97025.1 - 0.046 14.0 1.8 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal COG2 PF06148.11 EAX97025.1 - 0.068 13.3 8.3 0.37 10.9 0.8 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tho1_MOS11_C PF18592.1 EAX97025.1 - 0.082 12.7 1.9 0.13 12.1 0.3 2.2 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Fusion_gly PF00523.18 EAX97025.1 - 0.28 9.4 5.0 0.089 11.0 0.3 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 Syntaxin PF00804.25 EAX97025.1 - 0.4 10.3 18.5 0.083 12.6 14.7 1.8 2 1 0 2 2 2 0 Syntaxin Atg14 PF10186.9 EAX97025.1 - 1.9 7.5 9.7 0.82 8.7 6.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pup PF05639.11 EAX97025.1 - 2.9 8.9 12.2 3.6 8.6 0.0 3.2 3 1 0 3 3 3 0 Pup-like protein THOC7 PF05615.13 EAX97025.1 - 7.6 6.8 11.9 13 6.1 2.6 3.5 3 1 0 3 3 3 0 Tho complex subunit 7 Ank PF00023.30 EAX97026.1 - 9.3e-14 51.2 0.2 1.9e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX97026.1 - 3.5e-13 49.5 0.1 1.4e-07 31.7 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97026.1 - 1.1e-12 48.2 0.1 7.4e-11 42.4 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97026.1 - 1.4e-10 41.6 0.4 2.3e-10 40.9 0.4 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97026.1 - 3.4e-10 39.3 0.4 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat DUF3895 PF13034.6 EAX97026.1 - 0.13 12.3 0.6 7.2 6.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) DUF3447 PF11929.8 EAX97027.1 - 2e-38 130.2 6.2 2e-38 130.2 6.2 3.5 4 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX97027.1 - 2.6e-25 88.5 0.6 6.9e-09 36.1 0.0 5.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97027.1 - 6.3e-23 81.2 3.7 1.6e-16 60.6 0.9 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97027.1 - 2.6e-19 68.7 0.1 2.4e-08 34.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAX97027.1 - 1.1e-18 65.3 2.5 7.1e-07 29.1 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX97027.1 - 3.8e-16 58.9 0.7 1.7e-08 34.5 0.0 4.2 2 2 3 5 5 5 2 Ankyrin repeats (many copies) ATP13 PF12921.7 EAX97027.1 - 0.0057 16.5 1.0 0.0057 16.5 1.0 2.8 2 1 1 3 3 3 1 Mitochondrial ATPase expression DUF3718 PF12514.8 EAX97027.1 - 0.038 14.1 0.3 14 5.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) RRP36 PF06102.12 EAX97028.1 - 1.2e-34 119.7 15.7 1.5e-34 119.4 15.7 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 BRCA-2_OB3 PF09104.10 EAX97028.1 - 0.052 13.2 0.1 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF4407 PF14362.6 EAX97028.1 - 0.087 12.2 3.1 0.12 11.7 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nmad5 PF18757.1 EAX97028.1 - 0.23 11.6 5.2 0.62 10.2 0.6 2.2 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 Fungal_TACC PF12709.7 EAX97028.1 - 0.43 11.0 0.2 0.43 11.0 0.2 3.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-T_C PF15511.6 EAX97029.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX97029.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX97029.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX97029.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX97029.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX97029.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX97029.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX97029.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EAX97030.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX97030.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX97030.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX97030.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Pkinase PF00069.25 EAX97031.1 - 3.5e-48 164.3 0.0 4.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97031.1 - 1.1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97031.1 - 1.4e-07 31.2 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAX97031.1 - 0.0035 17.0 0.7 0.0095 15.5 0.7 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAX97031.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX97031.1 - 0.028 13.8 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX97031.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 EAX97033.1 - 2.3e-11 42.9 5.6 0.0005 20.0 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX97033.1 - 3.6e-10 39.4 3.1 6.2e-07 29.0 0.4 2.9 2 0 0 2 2 2 2 TPR repeat STI1 PF17830.1 EAX97033.1 - 3.7e-10 39.6 0.2 1e-09 38.2 0.2 1.8 1 0 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 EAX97033.1 - 2.2e-09 36.7 9.3 7e-05 22.5 0.3 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX97033.1 - 1.7e-07 31.8 0.5 0.0026 18.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAX97033.1 - 7.5e-07 29.5 0.4 0.0046 17.7 0.1 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX97033.1 - 1e-05 25.3 14.1 7.1e-05 22.7 0.5 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAX97033.1 - 1.9e-05 24.9 2.6 0.00077 19.7 0.3 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX97033.1 - 0.00047 20.3 6.9 0.22 12.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAX97033.1 - 0.00086 19.2 0.2 0.19 11.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAX97033.1 - 0.0022 18.5 0.6 0.0022 18.5 0.6 3.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAX97033.1 - 0.0099 15.7 0.1 0.56 10.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EAX97033.1 - 0.015 15.4 1.2 0.034 14.2 1.2 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 EAX97033.1 - 0.094 12.9 0.0 5.8 7.1 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EAX97033.1 - 0.12 12.8 0.9 0.78 10.2 0.8 2.1 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 EAX97033.1 - 0.23 12.0 9.0 0.55 10.8 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat YMF19 PF02326.15 EAX97034.1 - 0.09 13.6 2.3 0.21 12.4 0.3 2.3 2 1 0 2 2 2 0 Plant ATP synthase F0 DUF4097 PF13349.6 EAX97034.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative adhesin NICE-3 PF07406.11 EAX97034.1 - 0.25 11.3 8.6 1.3 9.0 8.6 2.0 1 1 0 1 1 1 0 NICE-3 protein DUF3082 PF11282.8 EAX97035.1 - 0.035 14.4 1.0 0.073 13.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) HemY_N PF07219.13 EAX97035.1 - 0.65 10.2 2.7 0.59 10.4 0.6 1.9 1 1 0 2 2 2 0 HemY protein N-terminus DUF4795 PF16043.5 EAX97036.1 - 0.005 16.5 17.1 0.0062 16.2 2.3 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) PTR PF12789.7 EAX97036.1 - 0.012 15.6 6.3 0.045 13.8 2.2 3.7 2 1 0 2 2 2 0 Phage tail repeat like TMP PF05017.14 EAX97038.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97039.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3053 PF11254.8 EAX97040.1 - 0.32 10.6 4.7 0.17 11.5 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3053) Ribosomal_L14e PF01929.17 EAX97041.1 - 3.2e-19 69.2 2.9 4.3e-19 68.8 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Sel1 PF08238.12 EAX97043.1 - 1.6e-05 25.4 3.3 0.041 14.6 0.4 3.0 2 0 0 2 2 2 2 Sel1 repeat DUF1837 PF08878.11 EAX97043.1 - 0.0059 16.4 1.1 0.014 15.2 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1837) TPR_1 PF00515.28 EAX97043.1 - 0.98 9.4 10.3 6.7 6.7 0.7 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Adenine_glyco PF03352.13 EAX97044.1 - 3e-73 245.3 0.5 3.4e-73 245.2 0.5 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HhH-GPD PF00730.25 EAX97044.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Spc7 PF08317.11 EAX97045.1 - 0.00015 20.8 59.0 0.00064 18.7 20.7 4.3 2 1 3 5 5 5 3 Spc7 kinetochore protein GAS PF13851.6 EAX97045.1 - 0.00062 19.2 56.5 0.0061 15.9 21.6 3.7 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EAX97045.1 - 0.0032 17.2 5.8 0.0032 17.2 5.8 7.5 4 2 4 8 8 8 1 Septum formation initiator Seryl_tRNA_N PF02403.22 EAX97045.1 - 0.0038 17.4 51.7 0.27 11.5 13.3 5.6 3 1 3 6 6 6 2 Seryl-tRNA synthetase N-terminal domain MS_channel PF00924.18 EAX97045.1 - 0.017 14.6 2.4 0.068 12.7 2.4 2.1 1 0 0 1 1 1 0 Mechanosensitive ion channel ZapB PF06005.12 EAX97045.1 - 0.035 14.6 4.0 0.035 14.6 4.0 8.0 4 2 1 5 5 4 0 Cell division protein ZapB ERM PF00769.19 EAX97045.1 - 0.088 12.6 52.0 0.67 9.7 39.8 3.6 1 1 2 3 3 3 0 Ezrin/radixin/moesin family MAD PF05557.13 EAX97045.1 - 1 7.6 53.2 0.51 8.6 18.1 3.0 1 1 2 3 3 3 0 Mitotic checkpoint protein DUF812 PF05667.11 EAX97045.1 - 1.5 7.6 50.3 0.29 10.0 45.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF3450 PF11932.8 EAX97045.1 - 2.2 7.5 47.3 0.13 11.6 3.3 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 EAX97045.1 - 2.3 8.0 58.0 0.62 9.9 4.1 4.0 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 EAX97045.1 - 3.4 6.2 49.6 0.13 10.9 41.8 2.1 1 1 0 2 2 2 0 AAA domain CALCOCO1 PF07888.11 EAX97045.1 - 3.9 6.2 49.4 0.27 10.1 29.5 2.5 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 EAX97045.1 - 4.2 6.9 51.7 5.5 6.5 37.2 4.5 2 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 EAX97045.1 - 4.5 7.3 31.7 5.1 7.1 9.8 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 EAX97045.1 - 4.7 6.6 54.0 10 5.5 31.0 2.7 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 EAX97045.1 - 5.1 7.1 61.4 0.41 10.7 24.9 4.6 1 1 3 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF997 PF06196.12 EAX97046.1 - 0.48 10.5 2.6 0.68 10.0 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF997) IBD PF10416.9 EAX97047.1 - 1.1e-17 64.2 0.1 1.6e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Nuc_sug_transp PF04142.15 EAX97048.1 - 1.3e-05 24.6 7.0 3.2e-05 23.3 6.4 2.1 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EAX97048.1 - 1.4e-05 25.3 13.5 1.4e-05 25.3 13.5 3.3 2 1 0 2 2 2 1 EamA-like transporter family UCH PF00443.29 EAX97049.1 - 3.7e-50 170.8 64.2 1.5e-27 96.8 7.0 5.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 EAX97050.1 - 5.4e-43 144.7 12.8 2.1e-13 49.9 0.1 5.6 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX97050.1 - 2.9e-11 43.2 4.7 0.026 14.5 0.1 4.9 5 0 0 5 5 5 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX97050.1 - 4.1e-06 26.8 8.0 0.013 15.5 0.1 4.9 5 0 0 5 5 5 2 RNA binding motif RRM_occluded PF16842.5 EAX97050.1 - 0.0022 17.8 0.1 0.17 11.7 0.0 2.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Herpes_BLRF2 PF05812.12 EAX97050.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF3109 PF11307.8 EAX97050.1 - 0.0029 17.4 0.9 1.8 8.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3109) RL PF17797.1 EAX97050.1 - 0.0034 17.3 0.6 4.6 7.3 0.0 2.9 3 0 0 3 3 3 2 RL domain RRM_5 PF13893.6 EAX97050.1 - 0.018 14.7 0.1 0.062 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF999 PF06198.11 EAX97050.1 - 0.036 14.1 0.7 0.12 12.4 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF999) Catalase-rel PF06628.12 EAX97050.1 - 0.11 12.8 0.0 0.45 10.7 0.0 2.1 1 0 0 1 1 1 0 Catalase-related immune-responsive PhetRS_B1 PF18262.1 EAX97050.1 - 0.16 12.2 5.3 9.7 6.5 0.1 4.0 4 0 0 4 4 4 0 Phe-tRNA synthetase beta subunit B1 domain TRM PF02005.16 EAX97051.1 - 5.2e-105 351.7 0.0 6.5e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EAX97051.1 - 1.4e-09 38.0 0.1 2.2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EAX97051.1 - 0.00016 21.2 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Myb_DNA-binding PF00249.31 EAX97052.1 - 5.8e-07 29.6 0.3 9e-07 29.0 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97052.1 - 0.00019 21.6 1.2 0.00038 20.6 1.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97052.1 - 0.00056 19.8 2.9 0.00064 19.6 1.5 1.8 1 1 1 2 2 2 1 Myb DNA-binding like DUF563 PF04577.14 EAX97053.1 - 6.6e-25 88.5 0.7 1.8e-24 87.0 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Pkinase PF00069.25 EAX97055.1 - 8.4e-58 195.8 0.0 2e-57 194.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97055.1 - 1.4e-32 113.0 0.0 5.8e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97055.1 - 1.5e-08 34.4 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX97055.1 - 5e-06 25.7 1.4 5.3e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EAX97055.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX97055.1 - 0.0055 16.7 0.0 0.091 12.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FAR1 PF03101.15 EAX97056.1 - 0.014 16.1 0.1 0.033 14.9 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain Transposase_mut PF00872.18 EAX97058.1 - 0.0049 15.8 0.2 0.0054 15.6 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Vta1 PF04652.16 EAX97058.1 - 0.014 15.4 0.3 0.018 15.0 0.3 1.1 1 0 0 1 1 1 0 Vta1 like Myb_DNA-binding PF00249.31 EAX97059.1 - 1.7e-28 98.5 0.9 3.5e-14 52.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97059.1 - 1.5e-18 66.8 7.1 1.1e-11 44.9 0.6 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97059.1 - 0.0012 18.7 2.5 0.0021 17.9 0.6 2.4 2 2 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX97059.1 - 0.049 13.8 1.6 0.94 9.7 0.2 2.9 2 1 1 3 3 3 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAX97059.1 - 0.066 13.4 0.5 0.066 13.4 0.5 2.1 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAX97059.1 - 0.083 13.3 5.0 3.1 8.3 0.1 2.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX97060.1 - 1.1e-23 83.2 2.0 4.7e-14 52.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97060.1 - 3.5e-17 62.4 1.1 5e-11 42.7 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX97060.1 - 1.1e-06 28.7 0.0 0.0083 16.1 0.0 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX97060.1 - 0.049 13.5 0.1 8.5 6.3 0.0 2.3 1 1 1 2 2 2 0 Myb DNA-binding like LAT PF15234.6 EAX97060.1 - 0.089 12.5 3.3 0.42 10.3 3.3 1.8 1 1 0 1 1 1 0 Linker for activation of T-cells Myb_DNA-bind_4 PF13837.6 EAX97060.1 - 2.7 8.4 6.0 3 8.3 1.3 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain ANAPC4_WD40 PF12894.7 EAX97061.1 - 4e-06 27.0 0.0 4.1e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Amidase02_C PF12123.8 EAX97063.1 - 0.0074 16.0 0.1 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAX97064.1 - 8.8e-11 41.3 3.1 3e-10 39.6 1.9 2.1 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX97064.1 - 0.066 11.9 1.4 2.3 6.8 1.2 2.9 2 1 0 2 2 2 0 DNA polymerase family B PapD_N PF00345.20 EAX97065.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain E2F_TDP PF02319.20 EAX97066.1 - 6.4e-05 22.9 0.5 0.031 14.3 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 EAX97067.1 - 6.3e-49 166.7 0.0 7.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97067.1 - 1.4e-24 86.8 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97067.1 - 0.00014 21.3 0.0 0.00051 19.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX97067.1 - 0.00027 19.8 0.0 0.054 12.3 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Kdo PF06293.14 EAX97067.1 - 0.015 14.7 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EAX97069.1 - 4.6e-22 77.9 2.9 4.9e-11 42.6 1.7 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97069.1 - 1.7e-18 66.6 7.6 6.2e-14 52.0 0.9 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97069.1 - 2e-07 30.8 1.9 1.7e-05 24.6 0.1 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EAX97069.1 - 0.058 13.5 0.0 0.79 9.8 0.0 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain P_proprotein PF01483.20 EAX97071.1 - 8.4e-12 44.9 0.0 2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Imm43 PF15570.6 EAX97071.1 - 0.044 13.8 1.0 0.12 12.3 0.2 2.1 2 0 0 2 2 2 0 Immunity protein 43 GPS2_interact PF15784.5 EAX97073.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97073.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Med30 PF11315.8 EAX97074.1 - 0.51 10.5 4.4 14 5.8 0.1 3.6 3 0 0 3 3 3 0 Mediator complex subunit 30 YebG PF07130.12 EAX97075.1 - 0.068 13.0 0.0 6.6 6.7 0.0 2.8 3 0 0 3 3 3 0 YebG protein ParE_toxin PF05016.15 EAX97075.1 - 0.11 13.1 0.0 4.3 8.0 0.0 2.7 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE TelA PF05816.11 EAX97075.1 - 0.18 10.8 0.8 0.28 10.2 0.8 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Ras PF00071.22 EAX97076.1 - 7.8e-09 35.3 0.0 8.3e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX97076.1 - 2.6e-08 34.1 0.0 2.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX97076.1 - 0.00061 19.3 0.0 0.00062 19.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX97076.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 EAX97076.1 - 0.021 14.2 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAX97076.1 - 0.03 14.7 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EAX97076.1 - 0.035 13.9 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EAX97076.1 - 0.036 14.0 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EAX97076.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAX97076.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX97076.1 - 0.086 13.1 0.0 0.086 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX97076.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1697 PF08002.11 EAX97077.1 - 0.21 12.0 3.2 0.2 12.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) FUSC PF04632.12 EAX97077.1 - 0.23 9.9 1.3 0.35 9.4 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 EAX97077.1 - 4 7.8 12.5 15 5.9 0.1 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) COMPASS-Shg1 PF05205.12 EAX97077.1 - 4.5 8.0 8.6 0.66 10.7 2.3 2.9 2 2 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1664 PF07889.12 EAX97077.1 - 5.4 7.1 14.5 6.9 6.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Lectin_leg-like PF03388.13 EAX97080.1 - 4e-16 59.1 0.2 4.1e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 Legume-like lectin family COMP PF11598.8 EAX97081.1 - 0.00014 22.3 3.6 0.011 16.2 0.6 3.0 2 0 0 2 2 2 2 Cartilage oligomeric matrix protein T4bSS_IcmS PF12608.8 EAX97081.1 - 0.12 12.7 1.2 1.4 9.3 0.4 2.8 2 1 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment Sod_Fe_N PF00081.22 EAX97081.1 - 0.2 12.1 4.1 0.66 10.5 0.9 3.4 1 1 1 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF4704 PF15787.5 EAX97082.1 - 4.9e-22 78.5 1.9 4.9e-22 78.5 1.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4704) Beach PF02138.18 EAX97082.1 - 2.7e-09 36.8 0.5 2.7e-09 36.8 0.5 3.8 3 1 1 4 4 4 2 Beige/BEACH domain Pkinase PF00069.25 EAX97083.1 - 1.9e-64 217.6 0.0 2.4e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97083.1 - 1.9e-33 115.9 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97083.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX97083.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAX97083.1 - 0.094 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EAX97083.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX97083.1 - 0.14 11.8 0.2 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_19 PF14559.6 EAX97084.1 - 6e-12 45.9 3.4 2.1e-05 24.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAX97084.1 - 2.2e-07 30.4 4.3 0.00015 21.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAX97084.1 - 2.9e-06 27.6 2.7 0.025 15.4 0.1 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAX97084.1 - 3.8e-06 26.5 2.8 6.7e-05 22.5 0.5 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAX97084.1 - 4e-05 23.6 4.6 0.00011 22.2 0.2 3.1 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EAX97084.1 - 0.00012 22.3 4.8 1 9.7 0.0 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAX97084.1 - 0.00059 20.3 5.3 0.11 13.2 0.3 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX97084.1 - 0.0033 17.4 4.3 2.7 8.2 0.7 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX97084.1 - 0.0036 17.4 0.3 0.0036 17.4 0.3 2.7 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX97084.1 - 0.0061 16.8 4.5 0.82 9.9 0.2 3.2 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EAX97084.1 - 0.0068 15.8 2.2 2.7 7.3 0.0 3.0 1 1 1 3 3 3 2 MalT-like TPR region TPR_21 PF09976.9 EAX97084.1 - 0.011 15.5 3.2 0.032 13.9 2.6 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 EAX97084.1 - 0.028 15.0 0.4 41 4.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAX97084.1 - 0.08 13.4 0.4 54 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX97086.1 - 4.8e-25 88.4 0.0 6.2e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97086.1 - 3.4e-13 49.5 0.0 5.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX97086.1 - 0.00028 19.8 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX97086.1 - 0.00093 19.2 0.0 0.0072 16.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAX97086.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EAX97086.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC PF00098.23 EAX97087.1 - 7.5e-06 25.8 14.3 1.7e-05 24.7 1.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EAX97087.1 - 0.00097 19.1 4.5 0.059 13.3 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EAX97087.1 - 0.0054 16.4 13.6 0.15 11.8 4.6 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 EAX97087.1 - 0.34 10.7 0.2 0.34 10.7 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 EAX97087.1 - 6.1 6.7 10.5 0.89 9.3 0.7 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger LRR_5 PF13306.6 EAX97088.1 - 1.1e-169 555.6 102.5 7.1e-43 145.6 16.5 7.4 1 1 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97088.1 - 8.5e-27 92.7 0.2 0.02 14.6 0.2 11.4 6 2 9 15 15 15 12 Leucine rich repeat A2M PF00207.22 EAX97088.1 - 2.5 8.0 8.9 17 5.3 0.1 5.6 5 2 1 6 6 6 0 Alpha-2-macroglobulin family Kelch_4 PF13418.6 EAX97089.1 - 2.3e-19 69.2 8.4 6.2e-06 26.1 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX97089.1 - 3e-09 36.8 2.3 0.044 14.1 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EAX97089.1 - 1.1e-07 31.9 3.7 0.19 12.1 0.0 4.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EAX97089.1 - 1.4e-06 28.2 0.3 0.39 10.8 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EAX97089.1 - 0.00017 21.1 0.0 0.32 10.6 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Phage_GPO PF05929.11 EAX97089.1 - 0.56 9.8 7.4 2 7.9 0.0 3.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Thioredoxin_6 PF13848.6 EAX97090.1 - 6.9e-27 94.5 7.5 3.6e-22 79.1 2.0 3.7 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin PF00085.20 EAX97090.1 - 3.3e-13 49.5 0.0 3.4e-06 27.0 0.0 4.4 4 1 0 4 4 4 3 Thioredoxin Ribosomal_S10 PF00338.22 EAX97091.1 - 5.9e-22 77.7 0.0 7.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e JAB PF01398.21 EAX97091.1 - 0.14 12.1 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Apolipoprotein PF01442.18 EAX97093.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pox_A32 PF04665.12 EAX97094.1 - 1.6e-05 24.5 0.8 2.6e-05 23.8 0.8 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX97094.1 - 0.0078 16.2 1.5 0.013 15.5 0.1 2.0 2 1 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX97094.1 - 0.0095 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX97094.1 - 0.033 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX97094.1 - 0.34 11.2 3.7 0.24 11.7 1.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) PTR PF12789.7 EAX97095.1 - 4.8e-33 113.0 20.5 6.5e-30 103.0 12.5 4.5 5 1 1 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX97095.1 - 0.081 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX97096.1 - 0.026 15.0 0.6 0.054 14.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX97097.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97098.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Peptidase_M60 PF13402.6 EAX97099.1 - 1.9e-65 221.1 0.5 3.2e-65 220.4 0.5 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 EAX97099.1 - 1.5e-26 92.5 0.0 3.4e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 EAX97099.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EAX97099.1 - 0.0063 16.9 2.2 0.027 14.9 0.0 3.2 4 0 0 4 4 4 1 GLEYA domain Orf78 PF06024.12 EAX97100.1 - 0.14 12.5 0.0 0.14 12.5 0.0 4.7 3 1 0 3 3 3 0 Orf78 (ac78) Ank_2 PF12796.7 EAX97101.1 - 5.2e-27 94.3 3.8 7.7e-11 42.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97101.1 - 4.9e-26 90.8 1.6 2.1e-11 44.1 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97101.1 - 1.1e-18 65.3 7.7 0.00011 22.4 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX97101.1 - 2.6e-17 62.7 1.5 7.2e-07 29.4 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX97101.1 - 1.3e-13 50.7 0.1 0.00069 19.9 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Mucin_bdg PF03272.13 EAX97101.1 - 0.11 12.6 0.4 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module Glyco_hydro_20 PF00728.22 EAX97102.1 - 1.9e-21 76.9 2.4 7e-20 71.7 2.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ECSCR PF15820.5 EAX97102.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CD99L2 PF12301.8 EAX97102.1 - 0.038 14.3 0.1 0.077 13.3 0.1 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Insulin_TMD PF17870.1 EAX97102.1 - 0.08 13.0 1.1 0.18 11.9 1.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MCM6_C PF18263.1 EAX97102.1 - 0.27 11.5 2.6 0.78 10.0 0.4 2.8 2 1 1 3 3 3 0 MCM6 C-terminal winged-helix domain DUF3042 PF11240.8 EAX97102.1 - 0.75 9.9 2.7 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) THEG PF14912.6 EAX97104.1 - 0.023 15.1 0.4 0.092 13.2 0.4 2.1 1 0 0 1 1 1 0 Testicular haploid expressed repeat Nas2_N PF18265.1 EAX97104.1 - 7.9 6.5 12.7 1.5 8.8 0.2 4.3 3 1 1 4 4 4 0 Nas2 N_terminal domain E2F_TDP PF02319.20 EAX97105.1 - 6.7e-12 45.3 0.1 7.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF1563 PF07599.11 EAX97105.1 - 0.087 12.9 0.1 0.32 11.1 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) DDE_Tnp_4 PF13359.6 EAX97106.1 - 5e-31 107.5 0.0 1.1e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.29 EAX97106.1 - 1.1e-10 41.4 1.8 1.6e-09 37.6 1.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAX97106.1 - 6.6e-08 32.5 1.0 3.5e-07 30.1 0.1 2.5 2 1 0 2 2 2 1 Transposase DDE domain UCH_1 PF13423.6 EAX97106.1 - 8.3e-05 22.3 2.6 0.0026 17.4 0.2 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX97106.1 - 0.0047 16.4 2.6 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase TMP PF05017.14 EAX97107.1 - 0.039 14.5 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF4106 PF13388.6 EAX97112.1 - 1.6e-96 324.1 5.4 1.6e-96 324.1 5.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) DUF3452 PF11934.8 EAX97112.1 - 0.14 11.7 0.5 0.39 10.3 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Ribosomal_L18_c PF14204.6 EAX97112.1 - 0.83 10.6 10.9 6.3 7.8 3.7 3.9 2 1 0 2 2 2 0 Ribosomal L18 C-terminal region Annexin PF00191.20 EAX97113.1 - 0.03 14.4 1.2 0.15 12.2 0.2 2.6 2 1 0 2 2 2 0 Annexin MULE PF10551.9 EAX97114.1 - 3.9e-10 40.0 1.7 4e-10 40.0 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX97114.1 - 0.0085 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Ank_2 PF12796.7 EAX97115.1 - 3.5e-16 59.5 0.5 9.6e-10 38.9 0.3 3.4 1 1 3 4 4 4 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX97115.1 - 5e-10 39.2 5.4 3.3e-08 33.4 0.0 3.1 4 0 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX97115.1 - 6.9e-10 39.3 0.3 5.2e-06 26.9 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97115.1 - 1.5e-09 37.3 0.5 0.09 13.4 0.1 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX97115.1 - 7.6e-09 35.7 1.0 0.0002 21.6 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97115.1 - 1.5e-05 25.2 0.2 0.034 14.6 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAX97116.1 - 8e-35 119.3 3.4 4.3e-11 43.3 0.4 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97116.1 - 6.4e-22 77.6 0.9 0.00044 20.8 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97116.1 - 7.9e-20 68.9 1.6 0.024 15.2 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX97116.1 - 5e-18 64.7 2.2 0.00021 21.6 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX97116.1 - 6e-14 51.9 3.5 0.001 19.3 0.1 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 EAX97117.1 - 3.7e-28 97.4 4.0 6.4e-14 51.9 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97117.1 - 3e-23 81.8 5.3 7.2e-16 58.2 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97117.1 - 3.2e-05 23.8 1.2 0.016 15.1 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX97117.1 - 6.3e-05 23.1 0.5 0.002 18.2 0.2 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX97117.1 - 0.00058 19.9 3.3 0.15 12.1 0.0 2.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX97117.1 - 0.027 14.9 7.1 0.44 11.0 0.4 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lycopene_cycl PF05834.12 EAX97117.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein EamA PF00892.20 EAX97118.1 - 1.5e-13 51.1 34.6 5.9e-08 33.0 14.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family FAM176 PF14851.6 EAX97118.1 - 0.12 12.0 2.1 2 8.1 0.1 2.4 2 0 0 2 2 2 0 FAM176 family TMEM51 PF15345.6 EAX97118.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3671 PF12420.8 EAX97118.1 - 0.48 10.5 3.2 13 5.9 1.9 2.9 3 0 0 3 3 3 0 Protein of unknown function OAD_gamma PF04277.13 EAX97118.1 - 4.7 7.9 0.0 4.7 7.9 0.0 3.2 3 1 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Spo0A_C PF08769.11 EAX97119.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Mor PF08765.11 EAX97119.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Mor transcription activator family DUF4107 PF13389.6 EAX97120.1 - 1e-71 240.3 4.0 1.3e-71 240.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX97121.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX97123.1 - 1.7e-153 509.0 11.7 2.2e-153 508.7 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX97123.1 - 0.04 14.3 0.5 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DUF2408 PF10303.9 EAX97123.1 - 4.2 7.9 6.3 2.1 8.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) T5orf172 PF10544.9 EAX97124.1 - 0.00016 22.2 0.3 0.00039 20.9 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX97124.1 - 0.0081 15.7 0.9 0.11 12.0 0.3 2.0 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX97124.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain GPS2_interact PF15784.5 EAX97125.1 - 0.12 12.8 1.4 0.18 12.2 1.4 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97125.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain L27_1 PF09058.10 EAX97127.1 - 0.0079 16.1 3.1 0.12 12.4 0.0 3.0 3 0 0 3 3 3 1 L27_1 CREPT PF16566.5 EAX97127.1 - 0.02 15.1 1.0 0.044 14.0 0.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EAX97127.1 - 1.5 9.0 7.8 0.64 10.2 1.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HEAT PF02985.22 EAX97128.1 - 0.014 15.6 3.2 6.1 7.4 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 EAX97128.1 - 1.5 9.4 5.7 18 6.0 0.4 3.7 3 1 1 4 4 4 0 HEAT-like repeat BATS PF06968.13 EAX97129.1 - 5.7e-27 93.7 0.0 1.3e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EAX97129.1 - 1.9e-10 41.4 0.2 3.8e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily YfkB PF08756.10 EAX97129.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 YfkB-like domain PDEase_II PF02112.15 EAX97129.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF4201 PF13870.6 EAX97130.1 - 0.0022 17.8 24.8 0.0022 17.8 24.8 7.5 5 1 2 7 7 7 4 Domain of unknown function (DUF4201) zf-Sec23_Sec24 PF04810.15 EAX97131.1 - 3.2e-06 27.1 2.4 3.2e-06 27.1 2.4 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-met PF12874.7 EAX97131.1 - 5.6 7.5 5.2 20 5.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1910 PF08928.10 EAX97132.1 - 0.056 13.4 0.1 0.27 11.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) CaMKII_AD PF08332.10 EAX97132.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Spidroin_MaSp PF11260.8 EAX97132.1 - 3.6 7.9 8.8 15 6.0 0.7 3.0 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Ank_2 PF12796.7 EAX97135.1 - 1.2e-101 333.4 32.3 4.5e-18 65.6 0.1 5.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97135.1 - 8.5e-49 162.0 11.9 6.4e-06 26.4 0.1 9.7 9 1 1 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX97135.1 - 1.1e-47 159.8 3.3 4.4e-10 39.9 0.1 7.4 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97135.1 - 2.9e-41 134.7 7.5 1.2e-05 25.3 0.0 9.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX97135.1 - 6.5e-39 131.5 8.2 1.7e-06 28.1 0.1 7.7 2 1 6 8 8 8 8 Ankyrin repeats (many copies) DUF3083 PF11281.8 EAX97135.1 - 0.00052 19.5 0.1 1.4 8.1 0.0 3.2 1 1 2 4 4 4 2 Protein of unknown function (DUF3083) Ank_2 PF12796.7 EAX97137.1 - 2.4e-40 137.0 4.9 2.2e-18 66.6 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97137.1 - 7.3e-28 96.6 3.5 7e-13 48.8 0.3 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX97137.1 - 7.5e-24 83.1 5.4 5.6e-06 26.6 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX97137.1 - 2.1e-23 82.1 1.2 2e-09 37.5 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97137.1 - 2.5e-20 70.4 0.7 6.5e-06 26.1 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat DPCD PF14913.6 EAX97138.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 DPCD protein family Bromodomain PF00439.25 EAX97139.1 - 2e-20 72.6 0.3 5e-20 71.4 0.3 1.7 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX97139.1 - 1.3e-05 25.2 3.3 5.7e-05 23.2 2.6 2.3 2 1 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation NumbF PF06311.12 EAX97139.1 - 0.0012 19.4 0.6 0.0026 18.3 0.4 1.7 2 0 0 2 2 2 1 NUMB domain JAB PF01398.21 EAX97140.1 - 2.8e-27 95.1 0.0 4.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EAX97140.1 - 1.7e-08 34.2 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 EAX97140.1 - 0.0001 22.7 0.0 0.00035 21.0 0.0 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EAX97140.1 - 0.063 13.3 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Ank_2 PF12796.7 EAX97141.1 - 3.9e-36 123.5 0.2 2e-15 57.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97141.1 - 9.8e-25 86.6 0.0 3.6e-08 33.8 0.0 5.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97141.1 - 1.9e-20 72.6 0.0 0.00013 22.1 0.0 6.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX97141.1 - 2.3e-20 72.1 0.0 0.0018 18.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX97141.1 - 5.1e-18 63.3 0.0 0.03 14.9 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat ATG16 PF08614.11 EAX97141.1 - 6.6e-07 29.8 105.8 0.024 14.9 12.2 7.4 2 2 3 6 6 6 4 Autophagy protein 16 (ATG16) GAS PF13851.6 EAX97141.1 - 0.001 18.5 19.2 0.001 18.5 19.2 6.6 3 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding ERM PF00769.19 EAX97141.1 - 0.0013 18.6 9.1 0.0013 18.6 9.1 5.5 3 1 3 6 6 6 1 Ezrin/radixin/moesin family BRE1 PF08647.11 EAX97141.1 - 0.0041 17.2 5.8 0.0041 17.2 5.8 8.1 4 3 2 6 6 6 1 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 EAX97141.1 - 0.01 15.6 120.2 0.35 10.7 21.5 5.1 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 EAX97141.1 - 0.026 14.7 121.9 0.2 11.7 31.2 6.3 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EAX97141.1 - 0.096 13.1 96.4 0.096 13.1 22.3 4.6 2 1 2 4 4 3 0 Fez1 HMMR_N PF15905.5 EAX97141.1 - 0.13 11.8 116.4 0.43 10.0 20.0 4.2 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor N-terminal VD10_N PF08476.10 EAX97141.1 - 0.52 10.0 2.8 11 5.8 0.1 3.7 3 0 0 3 3 3 0 Viral D10 N-terminal Lebercilin PF15619.6 EAX97141.1 - 2.2 7.9 121.2 0.51 10.0 19.2 6.0 3 1 2 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease MinE PF03776.14 EAX97141.1 - 2.8 8.0 15.9 0.93 9.5 1.3 4.4 4 0 0 4 4 4 0 Septum formation topological specificity factor MinE DUF812 PF05667.11 EAX97141.1 - 5.7 5.7 101.8 0.031 13.2 17.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF812) DUF267 PF03268.14 EAX97141.1 - 6.1 5.6 5.9 12 4.6 5.9 1.4 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 ISPD_C PF18706.1 EAX97142.1 - 0.031 13.9 2.7 0.037 13.7 2.7 1.1 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain S-antigen PF05756.11 EAX97142.1 - 0.046 14.1 0.6 0.15 12.4 0.6 1.8 1 1 0 1 1 1 0 S-antigen protein DASH_Duo1 PF08651.10 EAX97142.1 - 0.13 12.0 2.3 0.77 9.6 0.3 2.6 1 1 1 2 2 2 0 DASH complex subunit Duo1 DUF4108 PF13390.6 EAX97143.1 - 5.3e-57 191.8 8.0 5.9e-57 191.6 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PcfK PF14058.6 EAX97144.1 - 0.17 12.2 8.2 0.27 11.5 8.2 1.4 1 1 0 1 1 1 0 PcfK-like protein DUF2897 PF11446.8 EAX97144.1 - 0.99 9.3 3.5 2.2 8.2 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) COPIIcoated_ERV PF07970.12 EAX97147.1 - 1.3e-50 172.3 0.1 2.1e-50 171.6 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAX97147.1 - 4.9e-16 58.9 0.1 1.1e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FANCI_HD1 PF14679.6 EAX97148.1 - 0.21 11.6 3.2 0.55 10.2 0.2 3.3 3 0 0 3 3 3 0 FANCI helical domain 1 DUF5446 PF17522.2 EAX97149.1 - 0.11 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) KilA-N PF04383.13 EAX97150.1 - 9.9e-42 141.3 0.2 3.1e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain LOH1CR12 PF10158.9 EAX97150.1 - 0.38 10.8 2.8 1.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein PTR PF12789.7 EAX97153.1 - 0.88 9.7 7.4 0.33 11.0 1.2 2.9 1 1 0 2 2 2 0 Phage tail repeat like Pkinase PF00069.25 EAX97154.1 - 3.9e-29 101.8 0.0 1.8e-27 96.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97154.1 - 7.4e-23 81.1 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 EAX97154.1 - 2.6e-17 62.6 0.2 2.6e-08 34.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97154.1 - 1.6e-15 57.5 0.8 9.3e-15 55.0 0.4 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97154.1 - 1.1e-13 51.4 0.0 2e-06 28.2 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97154.1 - 1.5e-12 46.5 0.1 0.0015 18.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAX97154.1 - 2e-09 37.5 2.0 0.0068 16.8 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat YukC PF10140.9 EAX97154.1 - 0.0046 15.8 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Ank_2 PF12796.7 EAX97155.1 - 2.4e-75 249.1 43.1 2.3e-16 60.1 1.1 6.3 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97155.1 - 6.8e-75 246.6 18.5 1.1e-13 51.4 0.2 11.5 4 2 8 12 12 11 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX97155.1 - 2.8e-51 169.8 12.3 6.7e-07 29.5 0.0 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 EAX97155.1 - 5.5e-49 158.4 15.9 1.7e-05 24.8 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EAX97155.1 - 2.5e-43 145.6 6.0 6.6e-11 42.2 0.0 7.1 5 2 3 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97155.1 - 2.5e-38 129.9 4.8 2.5e-38 129.9 4.8 4.7 3 2 3 6 6 6 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX97155.1 - 5.4e-07 29.7 12.1 3.3 7.9 0.1 7.8 5 2 3 8 8 8 3 Protein of unknown function (DUF3718) YcxB PF14317.6 EAX97155.1 - 0.00023 20.8 0.7 76 3.1 0.0 5.9 6 0 0 6 6 6 0 YcxB-like protein ACD PF16671.5 EAX97155.1 - 0.00026 19.5 4.5 0.56 8.5 0.0 4.1 1 1 4 5 5 5 1 Actin cross-linking domain Prion PF00377.18 EAX97155.1 - 0.0061 16.4 1.9 8.1 6.3 0.0 5.1 2 1 3 6 6 6 1 Prion/Doppel alpha-helical domain ATP13 PF12921.7 EAX97155.1 - 0.013 15.4 0.9 0.013 15.4 0.9 3.4 3 1 0 4 4 4 0 Mitochondrial ATPase expression Clathrin PF00637.20 EAX97155.1 - 0.038 13.9 14.6 10 6.0 0.0 5.8 3 1 3 6 6 6 0 Region in Clathrin and VPS Clathrin_bdg PF15045.6 EAX97155.1 - 0.069 13.2 9.7 0.53 10.3 0.5 4.4 1 1 4 5 5 5 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Ntox33 PF15533.6 EAX97155.1 - 0.2 12.1 20.9 50 4.5 0.1 7.6 7 2 2 9 9 9 0 Bacterial toxin 33 DUF348 PF03990.14 EAX97155.1 - 7 6.5 13.5 65 3.4 0.0 6.7 8 0 0 8 8 8 0 G5-linked-Ubiquitin-like domain DUF2897 PF11446.8 EAX97156.1 - 0.18 11.7 2.1 0.36 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX97157.1 - 4.9e-07 29.5 2.7 4.9e-07 29.5 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX97157.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX97157.1 - 4.1e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX97157.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97157.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97157.1 - 0.0017 18.2 0.9 0.0034 17.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX97157.1 - 0.002 17.8 0.6 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97157.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX97157.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX97157.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX97157.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX97157.1 - 0.38 11.0 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAX97158.1 - 1.4e-79 266.9 10.2 1.9e-79 266.5 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX97158.1 - 0.038 14.5 0.3 0.048 14.1 0.3 1.2 1 0 0 1 1 1 0 Fez1 DUF2408 PF10303.9 EAX97158.1 - 0.042 14.4 0.5 0.072 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ZapB PF06005.12 EAX97158.1 - 0.27 11.7 1.5 1.1 9.7 0.2 2.4 3 0 0 3 3 3 0 Cell division protein ZapB GalP_UDP_transf PF01087.22 EAX97158.1 - 0.35 11.3 2.3 1.4 9.3 1.0 2.1 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX97159.1 - 2.7e-27 95.8 0.3 3e-27 95.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX97160.1 - 2.9e-49 165.0 29.6 2.2e-32 110.9 15.1 4.3 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX97160.1 - 0.026 14.2 1.0 0.05 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX97160.1 - 0.48 10.8 3.7 36 4.8 0.3 3.6 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF4404 PF14357.6 EAX97160.1 - 2.7 8.7 5.7 11 6.7 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) TMP PF05017.14 EAX97162.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97163.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_5 PF13306.6 EAX97165.1 - 6.8e-89 294.4 96.3 5.3e-17 62.0 2.0 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97165.1 - 3.9e-15 55.4 23.8 0.00022 20.9 1.5 8.8 5 2 6 11 11 11 8 Leucine rich repeat MecA PF05389.12 EAX97165.1 - 0.0099 15.5 2.3 0.018 14.7 2.3 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DUF4860 PF16152.5 EAX97165.1 - 0.015 15.2 2.8 1.7 8.5 0.1 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4860) LRR_4 PF12799.7 EAX97165.1 - 0.055 13.9 32.3 0.05 14.0 1.9 9.0 5 4 4 9 9 9 0 Leucine Rich repeats (2 copies) Vps53_N PF04100.12 EAX97166.1 - 2.2e-69 234.2 18.4 4.4e-69 233.3 18.4 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Baculo_PEP_C PF04513.12 EAX97166.1 - 0.00014 21.9 2.2 0.00014 21.9 2.2 3.3 4 0 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG7 PF10191.9 EAX97166.1 - 0.00017 20.0 14.3 0.0011 17.3 14.3 1.9 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) Vps54_N PF10475.9 EAX97166.1 - 0.0038 16.6 10.9 0.0038 16.6 10.9 2.1 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF948 PF06103.11 EAX97166.1 - 0.0043 17.3 4.4 1.3 9.3 0.6 3.8 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 EAX97166.1 - 0.0076 16.3 10.9 0.018 15.1 3.0 3.9 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 IFT20 PF14931.6 EAX97166.1 - 0.16 12.2 8.9 0.24 11.6 3.4 3.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF1664 PF07889.12 EAX97166.1 - 0.42 10.6 9.1 0.39 10.7 1.9 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 EAX97166.1 - 0.44 10.2 7.1 0.062 13.0 0.9 2.7 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF2884 PF11101.8 EAX97166.1 - 0.99 8.9 15.3 0.072 12.6 1.1 4.8 4 2 1 6 6 6 0 Protein of unknown function (DUF2884) BRE1 PF08647.11 EAX97166.1 - 2.1 8.5 9.8 7.6 6.7 2.0 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 EAX97166.1 - 3 7.1 8.0 8.6 5.6 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FeoB_Cyto PF17910.1 EAX97166.1 - 3.8 8.1 6.9 9 6.9 1.2 3.6 2 1 1 3 3 3 0 FeoB cytosolic helical domain DUF148 PF02520.17 EAX97166.1 - 6.7 6.9 14.2 0.69 10.0 3.4 3.7 3 1 0 3 3 3 0 Domain of unknown function DUF148 MCPsignal PF00015.21 EAX97166.1 - 7.6 6.3 9.9 3.9 7.3 4.7 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DPCD PF14913.6 EAX97167.1 - 2e-43 148.0 0.2 2.4e-43 147.7 0.2 1.0 1 0 0 1 1 1 1 DPCD protein family DUF1664 PF07889.12 EAX97168.1 - 6e-05 23.1 31.4 0.25 11.4 4.4 4.6 2 1 3 5 5 5 4 Protein of unknown function (DUF1664) Filament PF00038.21 EAX97168.1 - 0.00031 20.4 39.9 0.00031 20.4 39.9 3.0 2 1 0 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.19 EAX97168.1 - 0.0019 16.1 47.1 0.0025 15.7 47.1 1.1 1 0 0 1 1 1 1 Myosin tail Laminin_II PF06009.12 EAX97168.1 - 0.0036 17.3 5.5 0.0036 17.3 5.5 4.1 1 1 2 4 4 4 2 Laminin Domain II Spc7 PF08317.11 EAX97168.1 - 0.011 14.7 48.1 0.59 9.0 14.5 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAX97168.1 - 0.018 15.1 5.4 0.018 15.1 5.4 5.6 2 1 2 5 5 5 0 TPR/MLP1/MLP2-like protein rpo30_N PF12410.8 EAX97168.1 - 0.048 13.6 3.8 0.039 13.9 0.7 2.3 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Pox_A_type_inc PF04508.12 EAX97168.1 - 0.12 12.2 2.7 1.1 9.3 0.2 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SOGA PF11365.8 EAX97168.1 - 0.38 11.9 36.4 0.1 13.7 6.2 4.7 2 1 1 4 4 4 0 Protein SOGA CENP-F_leu_zip PF10473.9 EAX97168.1 - 0.58 10.2 50.1 1.7 8.7 7.4 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 EAX97168.1 - 0.69 9.1 51.3 0.36 10.0 30.1 3.9 1 1 2 4 4 3 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 EAX97168.1 - 0.96 9.6 46.4 0.48 10.6 7.8 5.4 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.10 EAX97168.1 - 1 9.2 8.4 42 4.1 0.0 5.4 5 1 1 6 6 6 0 DASH complex subunit Dam1 ArgoMid PF16487.5 EAX97168.1 - 1.2 9.4 5.4 3 8.2 0.1 3.9 4 0 0 4 4 4 0 Mid domain of argonaute NPV_P10 PF05531.12 EAX97168.1 - 1.4 9.4 28.4 6.8 7.2 2.1 6.3 2 1 4 7 7 7 0 Nucleopolyhedrovirus P10 protein Thioredoxin_8 PF13905.6 EAX97168.1 - 2.1 8.7 8.7 0.42 11.0 1.0 3.5 2 1 1 4 4 4 0 Thioredoxin-like WEMBL PF05701.11 EAX97168.1 - 2.1 6.9 39.8 0.57 8.8 34.9 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light AAA_13 PF13166.6 EAX97168.1 - 2.2 6.8 41.0 0.36 9.4 24.2 3.0 1 1 2 3 3 3 0 AAA domain GAS PF13851.6 EAX97168.1 - 2.2 7.6 56.8 0.12 11.7 8.5 4.7 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EAX97168.1 - 2.3 8.9 41.4 0.82 10.3 6.8 5.9 1 1 4 5 5 5 0 Initiation control protein YabA Med9 PF07544.13 EAX97168.1 - 2.6 8.2 39.2 0.033 14.3 5.7 6.0 3 2 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Lebercilin PF15619.6 EAX97168.1 - 3 7.5 57.0 0.25 11.0 7.3 5.3 1 1 3 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EAX97168.1 - 5.2 7.3 47.3 1.4 9.1 13.0 4.4 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 EAX97168.1 - 5.9 5.3 9.6 7.1 5.0 0.3 2.2 1 1 0 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 EAX97168.1 - 6 7.3 46.4 3.1 8.2 13.0 3.9 1 1 2 3 3 3 0 Fez1 DUF812 PF05667.11 EAX97168.1 - 6.4 5.5 49.0 2.4 6.9 1.9 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF812) GAF PF01590.26 EAX97169.1 - 0.00059 20.5 0.0 0.037 14.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain Ank_2 PF12796.7 EAX97170.1 - 2.5e-35 120.9 0.6 2.2e-13 50.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97170.1 - 1.5e-30 105.1 0.0 3.5e-09 37.0 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97170.1 - 3.2e-25 87.9 0.2 4e-08 33.4 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97170.1 - 7.4e-25 84.3 0.0 0.0021 18.4 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAX97170.1 - 2.4e-24 84.7 0.0 0.00024 21.4 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat DUF3083 PF11281.8 EAX97170.1 - 0.0045 16.4 0.0 1.6 8.0 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3083) DUF5049 PF16468.5 EAX97170.1 - 0.014 15.2 0.3 8.7 6.3 0.0 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF5049) GUN4_N PF16416.5 EAX97170.1 - 0.028 14.4 0.0 45 4.1 0.0 4.0 4 1 1 5 5 5 0 ARM-like repeat domain, GUN4-N terminal IF-2 PF11987.8 EAX97170.1 - 0.05 13.7 0.2 7 6.8 0.0 3.1 1 1 3 4 4 4 0 Translation-initiation factor 2 mTERF PF02536.14 EAX97170.1 - 0.09 11.7 0.0 0.55 9.1 0.0 2.1 1 1 0 1 1 1 0 mTERF RPAP1_C PF08620.10 EAX97171.1 - 9.2e-20 70.5 0.0 1.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal ArgoMid PF16487.5 EAX97171.1 - 0.042 14.1 0.2 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Mid domain of argonaute DUF1280 PF06918.14 EAX97172.1 - 0.0054 16.4 4.3 0.011 15.4 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1280) Kelch_6 PF13964.6 EAX97174.1 - 0.0027 17.9 11.3 1.6 9.1 0.1 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EAX97174.1 - 0.053 13.5 0.1 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 EAX97174.1 - 0.089 12.8 0.1 0.089 12.8 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain LRR_5 PF13306.6 EAX97176.1 - 6.5e-33 113.4 42.3 5.3e-17 62.0 15.7 4.7 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97176.1 - 8.1e-07 28.7 0.0 0.086 12.6 0.0 4.7 3 1 2 5 5 5 4 Leucine rich repeat IL1 PF00340.19 EAX97176.1 - 0.0045 16.6 0.4 0.63 9.7 0.0 3.6 3 0 0 3 3 3 1 Interleukin-1 / 18 LRR_4 PF12799.7 EAX97176.1 - 0.018 15.5 11.4 10 6.7 0.5 6.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PI-PLC-X PF00388.19 EAX97176.1 - 0.049 13.2 0.3 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Phosphatidylinositol-specific phospholipase C, X domain DUF3839 PF12943.7 EAX97178.1 - 7.9e-80 267.8 12.3 1e-79 267.5 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2353 PF09789.9 EAX97178.1 - 0.0015 18.0 0.4 0.0023 17.3 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) NTP_transf_6 PF06042.11 EAX97178.1 - 0.019 14.8 1.2 0.053 13.4 0.5 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Aminotran_1_2 PF00155.21 EAX97178.1 - 0.034 13.3 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2408 PF10303.9 EAX97178.1 - 0.038 14.5 0.5 0.073 13.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 EAX97178.1 - 0.082 13.2 1.4 0.12 12.6 0.5 1.9 2 1 0 2 2 2 0 Tho complex subunit 7 DUF3839 PF12943.7 EAX97179.1 - 1.8e-36 125.8 1.3 2.1e-36 125.6 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX97180.1 - 2.3e-38 130.5 0.5 4.7e-38 129.5 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX97180.1 - 0.048 12.9 0.2 0.16 11.2 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase Pox_A32 PF04665.12 EAX97181.1 - 3.8e-07 29.8 4.0 5.2e-07 29.4 4.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX97181.1 - 0.011 15.3 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX97181.1 - 0.039 13.7 0.2 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Elong_Iki1 PF10483.9 EAX97181.1 - 0.052 13.0 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 RNA_helicase PF00910.22 EAX97181.1 - 0.13 12.7 0.9 0.56 10.6 0.1 2.5 2 1 0 3 3 3 0 RNA helicase DUF3783 PF12646.7 EAX97181.1 - 0.25 11.3 1.9 1.3 9.0 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX97181.1 - 1.1 9.4 9.8 5.2 7.3 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF2897 PF11446.8 EAX97182.1 - 0.38 10.7 2.3 0.8 9.6 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) SH3BGR PF04908.15 EAX97182.1 - 1.3 9.2 4.1 1.2 9.3 3.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF4108 PF13390.6 EAX97183.1 - 1.3e-57 193.8 4.4 1.4e-57 193.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX97185.1 - 4.6e-96 322.6 5.6 5.3e-96 322.4 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF4106 PF13388.6 EAX97186.1 - 7.9e-162 539.2 46.9 7.9e-162 539.2 46.9 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX97186.1 - 0.0027 18.0 2.9 0.044 14.1 0.2 3.1 3 0 0 3 3 3 1 Kidney androgen-regulated Peptidase_C1 PF00112.23 EAX97187.1 - 2e-75 253.6 13.9 2.5e-75 253.3 13.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX97187.1 - 5.7e-11 42.7 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAX97187.1 - 0.00059 18.7 3.9 0.022 13.5 0.7 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Spc7 PF08317.11 EAX97188.1 - 3.2e-06 26.3 72.1 4.5e-05 22.5 34.4 33.1 2 1 29 34 34 34 20 Spc7 kinetochore protein KASH_CCD PF14662.6 EAX97188.1 - 8.5e-05 22.5 185.8 0.00036 20.4 40.3 31.5 3 2 30 33 33 33 18 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EAX97188.1 - 0.001 19.1 6.9 0.001 19.1 6.9 84.8 18 13 69 97 97 97 21 bZIP transcription factor Cep57_CLD_2 PF14197.6 EAX97188.1 - 0.0015 18.6 13.6 0.0015 18.6 13.6 56.1 18 16 31 53 53 53 8 Centrosome localisation domain of PPC89 ERM PF00769.19 EAX97188.1 - 0.0017 18.3 23.6 0.0017 18.3 23.6 27.2 2 1 23 27 27 27 11 Ezrin/radixin/moesin family LRR_5 PF13306.6 EAX97190.1 - 1.7e-41 141.2 25.5 4.1e-19 68.8 8.4 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97190.1 - 3.3e-12 46.0 0.0 0.02 14.6 0.0 4.5 4 1 0 4 4 4 4 Leucine rich repeat Gly_rich PF12810.7 EAX97191.1 - 6.7e-39 134.3 26.2 8.1e-39 134.0 26.2 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX97192.1 - 2.6e-24 86.5 35.0 3.8e-24 86.0 35.0 1.2 1 0 0 1 1 1 1 Glycine rich protein MULE PF10551.9 EAX97193.1 - 0.00074 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain LuxE PF04443.12 EAX97193.1 - 0.0064 15.6 0.4 0.0088 15.1 0.2 1.3 1 1 0 1 1 1 1 Acyl-protein synthetase, LuxE Transposase_mut PF00872.18 EAX97193.1 - 0.035 13.0 0.3 0.056 12.3 0.3 1.4 1 1 0 1 1 1 0 Transposase, Mutator family Gly-zipper_Omp PF13488.6 EAX97194.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAX97194.1 - 0.49 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) CDPS PF16715.5 EAX97196.1 - 0.031 13.9 1.7 0.052 13.2 1.7 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF4278 PF14105.6 EAX97196.1 - 0.13 12.7 1.5 0.33 11.4 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) SLATT_6 PF18169.1 EAX97196.1 - 0.19 11.3 0.7 0.25 10.9 0.7 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 HIP1_clath_bdg PF16515.5 EAX97196.1 - 0.59 10.8 4.4 0.72 10.5 2.0 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5565 PF17720.1 EAX97198.1 - 0.12 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) PDGLE PF13190.6 EAX97199.1 - 0.1 12.5 0.1 0.54 10.2 0.1 2.0 2 0 0 2 2 2 0 PDGLE domain DUF2807 PF10988.8 EAX97199.1 - 4 7.2 11.3 0.77 9.5 4.6 3.2 3 1 1 4 4 4 0 Putative auto-transporter adhesin, head GIN domain EamA PF00892.20 EAX97200.1 - 2.4e-09 37.5 29.3 3.5e-06 27.2 12.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family SdpI PF13630.6 EAX97200.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.8 3 1 1 4 4 4 0 SdpI/YhfL protein family Guanylate_cyc PF00211.20 EAX97201.1 - 6.3e-42 143.3 0.0 1.3e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX97201.1 - 1.1e-10 41.7 0.7 3.5e-10 40.0 0.7 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EAX97201.1 - 1.7e-05 25.0 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAX97201.1 - 0.001 19.1 0.1 0.0026 17.7 0.1 1.7 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX97201.1 - 0.018 14.5 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Mis12 PF05859.12 EAX97201.1 - 0.022 14.8 0.0 0.11 12.6 0.0 2.2 1 0 0 1 1 1 0 Mis12 protein Myb_DNA-bind_6 PF13921.6 EAX97202.1 - 1.1e-13 51.2 6.4 2.3e-07 31.0 0.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX97202.1 - 3.6e-13 49.5 5.8 5.2e-11 42.6 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97202.1 - 0.00071 19.4 0.4 0.0038 17.1 0.0 2.1 1 1 1 2 2 2 1 Myb DNA-binding like HMG_box PF00505.19 EAX97204.1 - 6.2e-15 55.4 6.1 8.4e-15 54.9 6.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX97204.1 - 9.7e-10 38.9 6.0 1.4e-09 38.4 6.0 1.2 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 EAX97204.1 - 0.00017 22.2 0.4 0.00021 21.9 0.4 1.3 1 0 0 1 1 1 1 YABBY protein ALIX_LYPXL_bnd PF13949.6 EAX97204.1 - 0.0079 15.5 0.4 0.0085 15.4 0.4 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FMP23 PF17315.2 EAX97204.1 - 0.038 14.2 1.3 0.15 12.2 0.8 1.9 2 0 0 2 2 2 0 Found in mitochondrial proteome ALMS_motif PF15309.6 EAX97204.1 - 0.046 14.2 4.7 0.071 13.6 4.7 1.3 1 0 0 1 1 1 0 ALMS motif RtcB PF01139.17 EAX97205.1 - 2e-144 481.8 0.0 2.4e-144 481.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ras PF00071.22 EAX97206.1 - 3.5e-54 182.8 0.2 4e-54 182.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX97206.1 - 1.8e-32 112.1 0.1 3e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX97206.1 - 8.2e-18 64.5 0.0 9.7e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX97206.1 - 4.9e-08 32.6 0.0 5.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX97206.1 - 3e-06 27.3 0.1 4.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX97206.1 - 3.2e-06 26.7 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX97206.1 - 8.4e-05 22.3 0.0 0.0027 17.4 0.0 2.3 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAX97206.1 - 0.0012 18.5 0.6 0.016 14.7 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX97206.1 - 0.0039 17.1 0.3 0.077 12.9 0.2 2.4 1 1 2 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EAX97206.1 - 0.0054 17.0 0.2 0.025 14.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX97206.1 - 0.0084 16.5 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EAX97206.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 EAX97206.1 - 0.009 16.4 0.1 0.017 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAX97206.1 - 0.016 15.1 0.1 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EAX97206.1 - 0.028 13.9 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAX97206.1 - 0.029 14.1 0.2 0.066 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAX97206.1 - 0.054 13.3 0.3 1.8 8.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EAX97206.1 - 0.08 12.5 0.8 0.96 9.0 0.3 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAX97206.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAX97206.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 EAX97207.1 - 1.8e-26 93.1 0.4 2.3e-26 92.8 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97207.1 - 4.2e-14 52.5 0.1 6.1e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX97207.1 - 2.9e-07 29.6 0.3 4.1e-07 29.1 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX97207.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX97207.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EAX97207.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family DUF2225 PF09986.9 EAX97208.1 - 0.027 14.2 1.1 0.045 13.5 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TTRAP PF14203.6 EAX97209.1 - 0.0018 18.2 1.4 32 4.6 0.0 4.8 3 1 1 4 4 4 3 Putative tranposon-transfer assisting protein CheZ PF04344.13 EAX97209.1 - 0.03 14.3 0.5 0.17 11.8 0.1 2.5 2 1 0 3 3 3 0 Chemotaxis phosphatase, CheZ FAM25 PF15825.5 EAX97209.1 - 0.51 10.7 3.7 1.2 9.5 0.8 3.0 2 0 0 2 2 2 0 FAM25 family LRR_6 PF13516.6 EAX97210.1 - 9.5 6.6 13.7 2.9 8.2 2.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Myb_DNA-binding PF00249.31 EAX97211.1 - 1.5e-29 101.9 2.5 9.9e-14 51.3 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97211.1 - 2e-29 101.6 1.8 7e-18 64.6 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97211.1 - 1.8e-05 24.5 0.6 0.00084 19.2 0.2 2.1 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX97211.1 - 3.2e-05 23.9 0.2 0.055 13.5 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX97211.1 - 0.0036 17.5 0.6 0.083 13.1 0.2 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX97211.1 - 0.018 15.1 0.9 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAX97211.1 - 0.039 14.3 4.7 3.4 8.1 0.5 3.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Gluconate_2-dh3 PF13618.6 EAX97212.1 - 0.22 11.8 6.0 0.7 10.1 4.3 2.5 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Kelch_4 PF13418.6 EAX97213.1 - 1.2e-17 63.6 2.8 5.2e-05 23.2 0.2 4.4 2 1 2 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX97213.1 - 4.7e-12 45.7 1.3 0.042 14.1 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAX97213.1 - 4.8e-10 39.0 4.9 9.8e-05 22.2 0.2 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EAX97213.1 - 5.4e-10 39.3 1.4 0.00029 21.0 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX97213.1 - 9.7e-10 37.9 0.6 0.15 11.6 0.1 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EAX97213.1 - 1.3e-09 37.8 0.9 0.056 13.4 0.1 4.5 4 0 0 4 4 4 3 Kelch motif PolyA_pol PF01743.20 EAX97214.1 - 3.7e-18 66.2 0.1 6.3e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAX97214.1 - 7e-15 54.5 0.1 1.9e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Aminoglyc_resit PF10706.9 EAX97214.1 - 0.0016 18.2 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase GED PF02212.18 EAX97214.1 - 0.015 15.4 0.5 0.051 13.7 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain Myb_DNA-binding PF00249.31 EAX97215.1 - 3.2e-29 100.9 4.1 1.8e-17 63.3 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97215.1 - 1.6e-23 82.7 1.5 4.5e-13 49.2 0.1 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX97215.1 - 1.4e-06 28.3 0.1 0.012 15.6 0.1 2.6 1 1 1 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EAX97215.1 - 0.0034 17.7 2.4 0.16 12.3 1.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 EAX97215.1 - 0.0034 17.2 0.6 2.7 8.0 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX97215.1 - 0.043 14.2 7.7 0.57 10.6 5.3 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4107 PF13389.6 EAX97218.1 - 4.6e-73 244.7 4.6 5.5e-73 244.5 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX97218.1 - 0.067 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Lipoxygenase PF00305.19 EAX97218.1 - 0.17 10.2 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase START PF01852.19 EAX97220.1 - 9.8e-12 44.7 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 EAX97220.1 - 0.026 14.5 0.0 0.038 14.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) TFIIE_beta PF02186.15 EAX97220.1 - 0.073 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain COPR5 PF15340.6 EAX97221.1 - 0.07 13.8 2.3 0.08 13.6 2.3 1.0 1 0 0 1 1 1 0 Cooperator of PRMT5 family DUF2956 PF11169.8 EAX97221.1 - 2.7 8.3 7.7 3.5 7.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NARP1 PF12569.8 EAX97221.1 - 7.3 5.4 11.0 7.3 5.4 11.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 B56 PF01603.20 EAX97222.1 - 3.5e-39 135.0 2.7 6e-29 101.3 0.4 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Ank_2 PF12796.7 EAX97223.1 - 2.3e-77 255.6 21.6 8.6e-15 55.1 0.4 10.6 4 3 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97223.1 - 2.6e-57 190.5 16.6 2.3e-12 47.1 0.0 13.9 6 3 7 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97223.1 - 6.4e-52 172.9 9.9 3.7e-08 33.5 0.2 13.8 8 4 9 17 17 17 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97223.1 - 3.3e-46 149.9 22.0 0.0091 16.4 0.0 19.0 21 0 0 21 21 21 10 Ankyrin repeat Ank PF00023.30 EAX97223.1 - 6.7e-33 111.7 2.1 0.003 17.9 0.1 14.9 15 1 0 15 15 15 6 Ankyrin repeat DUF3447 PF11929.8 EAX97223.1 - 1.4e-13 50.6 16.1 3.4e-11 43.0 0.3 7.1 4 2 4 8 8 8 2 Domain of unknown function (DUF3447) ODC_AZ PF02100.17 EAX97223.1 - 0.13 12.3 0.3 3.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Ornithine decarboxylase antizyme OSTbeta PF15048.6 EAX97225.1 - 0.035 14.3 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein NFRKB_winged PF14465.6 EAX97225.1 - 0.064 13.5 0.1 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 NFRKB Winged Helix-like DUF3361 PF11841.8 EAX97226.1 - 0.0051 16.8 0.2 0.0051 16.8 0.2 3.2 3 2 1 4 4 4 1 Domain of unknown function (DUF3361) VHS PF00790.19 EAX97226.1 - 0.038 13.8 0.2 0.13 12.1 0.2 1.9 1 0 0 1 1 1 0 VHS domain ELFV_dehydrog PF00208.21 EAX97227.1 - 1.4e-79 267.3 0.1 1.7e-79 267.0 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EAX97227.1 - 1.3e-49 167.3 0.0 4.7e-49 165.6 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 EAX97227.1 - 0.051 13.6 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rap_GAP PF02145.15 EAX97228.1 - 1e-44 152.3 0.1 1e-44 152.3 0.1 2.4 3 0 0 3 3 3 1 Rap/ran-GAP DUF3447 PF11929.8 EAX97229.1 - 9.3e-35 118.4 9.2 9.3e-35 118.4 9.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97229.1 - 0.00043 20.8 0.2 0.0041 17.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97229.1 - 0.0077 16.8 0.2 0.38 11.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97229.1 - 0.13 12.9 0.7 5.6 7.9 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeat DUF5600 PF18150.1 EAX97230.1 - 0.049 14.2 0.7 0.19 12.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Phasin PF05597.11 EAX97231.1 - 0.0033 17.4 3.9 0.0084 16.1 1.4 2.0 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) LemA PF04011.12 EAX97231.1 - 0.022 14.6 2.6 0.036 13.9 2.3 1.5 1 1 0 1 1 1 0 LemA family FlaC_arch PF05377.11 EAX97231.1 - 0.042 14.3 5.0 3.9 8.0 0.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EAX97231.1 - 0.05 13.8 12.0 0.052 13.8 5.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EAX97231.1 - 0.06 13.6 11.1 0.039 14.2 6.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAX97231.1 - 0.071 13.7 0.6 3.3 8.4 0.0 2.5 2 1 0 2 2 2 0 SlyX Uds1 PF15456.6 EAX97231.1 - 0.075 13.2 0.2 0.075 13.2 0.2 2.8 1 1 0 2 2 2 0 Up-regulated During Septation gpW PF02831.15 EAX97231.1 - 0.11 12.4 0.1 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 gpW Phage_GP20 PF06810.11 EAX97231.1 - 0.12 12.1 10.7 2 8.2 10.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF5129 PF17173.4 EAX97231.1 - 0.21 10.7 1.4 0.23 10.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF4094 PF13334.6 EAX97231.1 - 0.25 11.8 10.9 5.7 7.4 0.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) GPS2_interact PF15784.5 EAX97231.1 - 0.32 11.5 11.6 1.2 9.6 6.3 2.5 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FlxA PF14282.6 EAX97231.1 - 0.36 10.8 12.5 3.4 7.7 0.7 3.2 2 1 1 3 3 3 0 FlxA-like protein I_LWEQ PF01608.17 EAX97231.1 - 0.46 10.7 10.2 4 7.7 1.6 2.1 1 1 1 2 2 2 0 I/LWEQ domain PspA_IM30 PF04012.12 EAX97231.1 - 0.5 9.9 6.4 0.74 9.3 2.7 2.1 2 0 0 2 2 2 0 PspA/IM30 family CENP-Q PF13094.6 EAX97231.1 - 0.65 10.2 7.6 1 9.6 7.6 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 EAX97231.1 - 0.74 10.2 16.4 0.38 11.2 8.1 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TSC22 PF01166.18 EAX97231.1 - 0.8 10.1 10.9 2.4 8.5 0.4 4.0 2 1 2 4 4 4 0 TSC-22/dip/bun family Atg14 PF10186.9 EAX97231.1 - 0.95 8.5 18.7 1.7 7.6 18.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 EAX97231.1 - 0.96 9.9 9.4 0.95 10.0 0.3 3.2 2 1 1 3 3 3 0 Cell division protein ZapB MYO10_CC PF16735.5 EAX97231.1 - 1.9 8.6 7.7 6.5 6.9 0.3 3.1 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain CREPT PF16566.5 EAX97231.1 - 2.5 8.2 9.9 1.3 9.2 6.8 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Cep57_CLD PF14073.6 EAX97231.1 - 2.8 7.9 15.9 6.1 6.8 15.9 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 bZIP_1 PF00170.21 EAX97231.1 - 5.1 7.3 17.5 2.7 8.1 4.3 3.3 3 0 0 3 3 3 0 bZIP transcription factor UPF0242 PF06785.11 EAX97231.1 - 5.6 7.0 17.0 81 3.2 17.0 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EAX97231.1 - 6.1 6.0 18.6 0.74 9.0 11.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 EAX97231.1 - 6.5 6.5 17.7 30 4.4 17.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) MRP-S27 PF10037.9 EAX97232.1 - 0.0047 15.8 1.5 0.0053 15.7 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 APG6_N PF17675.1 EAX97232.1 - 0.013 16.1 1.5 0.015 15.9 1.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Sec34 PF04136.15 EAX97232.1 - 0.014 15.3 4.4 0.036 14.0 3.9 1.7 1 1 0 1 1 1 0 Sec34-like family IFP_35_N PF07334.13 EAX97232.1 - 0.017 15.2 1.9 0.021 14.9 1.0 1.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CLZ PF16526.5 EAX97232.1 - 0.038 14.4 1.2 0.06 13.7 1.2 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C4H2 PF10146.9 EAX97232.1 - 0.041 14.2 3.1 0.048 14.0 3.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein CREPT PF16566.5 EAX97232.1 - 0.048 13.8 1.2 0.058 13.6 1.2 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Phytochelatin_C PF09328.10 EAX97232.1 - 0.068 12.5 1.2 0.086 12.1 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1984) DUF2400 PF09674.10 EAX97232.1 - 0.077 13.0 1.7 0.088 12.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CCAP PF11105.8 EAX97232.1 - 0.14 12.1 1.7 0.19 11.7 1.7 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Acylphosphatase PF00708.18 EAX97232.1 - 0.15 12.5 1.4 0.85 10.1 0.3 2.1 1 1 1 2 2 2 0 Acylphosphatase DUF4342 PF14242.6 EAX97232.1 - 0.15 12.0 2.2 3.2 7.8 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4342) Tnp_22_trimer PF17489.2 EAX97232.1 - 1.3 9.0 5.5 0.68 9.9 1.9 2.1 1 1 1 2 2 2 0 L1 transposable element trimerization domain DUF1798 PF08807.10 EAX97234.1 - 0.077 13.1 1.6 3 8.0 0.1 3.0 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) Pkinase PF00069.25 EAX97236.1 - 9.1e-78 261.3 0.0 2.3e-77 259.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97236.1 - 2.5e-47 161.4 0.0 4.7e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX97236.1 - 3.9e-05 22.6 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX97236.1 - 0.00023 20.6 0.0 0.00053 19.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.22 EAX97236.1 - 0.0056 16.8 0.0 5 7.7 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 EAX97236.1 - 0.0065 16.9 0.0 0.029 14.9 0.0 2.2 1 1 0 1 1 1 1 HEAT-like repeat APH PF01636.23 EAX97236.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Vac14_Fab1_bd PF12755.7 EAX97236.1 - 0.011 16.3 0.1 0.1 13.2 0.1 2.7 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region ABC1 PF03109.16 EAX97236.1 - 0.031 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC1 family U3snoRNP10 PF12397.8 EAX97236.1 - 0.04 14.3 3.4 47 4.4 0.1 4.8 4 1 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EAX97236.1 - 0.063 13.7 0.0 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats FTA2 PF13095.6 EAX97236.1 - 0.07 12.7 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAX97236.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTR PF12789.7 EAX97237.1 - 3.1e-47 158.5 29.1 1.2e-31 108.6 14.2 4.3 2 2 2 4 4 4 2 Phage tail repeat like PBP5_C PF07943.13 EAX97237.1 - 0.022 15.0 0.4 0.26 11.5 0.0 2.6 2 1 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DUF4116 PF13475.6 EAX97237.1 - 0.044 13.5 0.9 0.085 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Ank_2 PF12796.7 EAX97240.1 - 2.3e-46 156.3 7.5 3.3e-17 62.8 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97240.1 - 3.8e-32 109.9 1.0 1.2e-08 35.0 0.1 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97240.1 - 5.3e-31 106.6 0.1 1.7e-07 31.7 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX97240.1 - 2.5e-25 87.8 0.0 3e-05 24.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAX97240.1 - 1.5e-23 80.3 0.9 0.0019 18.5 0.0 6.9 7 1 0 7 7 7 5 Ankyrin repeat Spc7 PF08317.11 EAX97240.1 - 0.00093 18.2 1.6 0.0014 17.5 1.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.21 EAX97240.1 - 0.0016 18.5 2.4 0.0016 18.5 2.4 2.5 3 1 1 4 4 4 1 bZIP transcription factor Yuri_gagarin PF15934.5 EAX97240.1 - 0.0073 16.2 4.0 0.013 15.4 4.0 1.4 1 0 0 1 1 1 1 Yuri gagarin DUF4201 PF13870.6 EAX97240.1 - 0.01 15.6 2.2 0.01 15.6 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.7 EAX97240.1 - 0.017 15.2 2.2 0.017 15.2 2.2 2.2 2 0 0 2 2 2 0 Tropomyosin like SHE3 PF17078.5 EAX97240.1 - 0.018 14.8 6.9 0.018 14.8 6.9 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Nup54 PF13874.6 EAX97240.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 EAX97240.1 - 0.087 12.1 4.9 0.14 11.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RLL PF10036.9 EAX97240.1 - 0.095 12.5 8.4 0.1 12.4 2.3 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein TMF_TATA_bd PF12325.8 EAX97240.1 - 0.15 12.3 3.3 0.13 12.5 1.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 EAX97240.1 - 0.21 10.4 2.4 0.13 11.1 0.7 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fungal_TACC PF12709.7 EAX97240.1 - 0.35 11.4 6.9 6.3 7.3 1.0 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 EAX97240.1 - 1.4 9.3 8.8 0.65 10.4 2.9 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Uso1_p115_C PF04871.13 EAX97240.1 - 1.6 9.1 6.5 0.38 11.1 2.8 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 EAX97240.1 - 2.1 8.1 8.4 0.25 11.2 3.5 2.0 2 1 0 2 2 1 0 Septum formation initiator APG6_N PF17675.1 EAX97240.1 - 2.2 8.8 7.6 0.43 11.1 3.1 2.1 2 1 1 3 3 2 0 Apg6 coiled-coil region ZapB PF06005.12 EAX97240.1 - 9.3 6.8 11.7 4.3 7.8 7.7 2.5 2 1 0 2 2 2 0 Cell division protein ZapB TFIIA PF03153.13 EAX97241.1 - 0.004 17.2 1.3 0.004 17.2 1.3 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 EAX97241.1 - 0.047 13.1 12.9 0.071 12.5 12.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EAX97241.1 - 0.49 8.6 7.7 0.54 8.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4665 PF15679.5 EAX97241.1 - 0.53 10.9 2.7 1.4 9.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) SDA1 PF05285.12 EAX97241.1 - 0.65 9.4 11.4 0.84 9.0 11.4 1.2 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 EAX97241.1 - 0.87 7.3 5.2 0.89 7.3 5.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GET2 PF08690.10 EAX97241.1 - 1.1 8.9 7.8 1.5 8.5 7.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 eIF-3c_N PF05470.12 EAX97241.1 - 2.1 6.5 13.3 3 6.1 13.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 EAX97241.1 - 2.2 6.3 17.8 3.8 5.5 17.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3718 PF12514.8 EAX97242.1 - 0.011 15.9 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) GshA PF08886.11 EAX97242.1 - 0.031 12.9 0.0 0.051 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase Ank_2 PF12796.7 EAX97244.1 - 1.2e-18 67.4 0.0 5.4e-18 65.4 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97244.1 - 5.5e-15 55.5 0.0 9.5e-09 35.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97244.1 - 1.9e-11 43.1 0.4 0.02 15.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX97244.1 - 2.9e-11 43.3 0.0 0.00061 20.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX97244.1 - 1.4e-10 41.2 0.2 7.2e-05 23.0 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.15 EAX97244.1 - 7.3e-05 22.8 0.5 0.00021 21.3 0.5 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch IMPa_helical PF18642.1 EAX97245.1 - 0.045 14.2 0.1 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain EF-hand_7 PF13499.6 EAX97246.1 - 8.7e-12 45.3 0.1 0.00015 22.2 0.0 6.3 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX97246.1 - 1.5e-09 37.0 0.0 1.4 9.1 0.0 7.2 8 0 0 8 8 8 3 EF-hand domain EF-hand_8 PF13833.6 EAX97246.1 - 4.9e-09 35.9 0.2 0.17 11.8 0.0 6.1 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_1 PF00036.32 EAX97246.1 - 0.0001 21.6 0.0 16 5.3 0.0 6.6 9 0 0 9 9 9 2 EF hand TPR_MLP1_2 PF07926.12 EAX97247.1 - 0.00013 22.1 28.7 0.00013 22.1 28.7 7.8 3 2 2 7 7 7 3 TPR/MLP1/MLP2-like protein Filament PF00038.21 EAX97247.1 - 0.0035 17.0 15.4 0.0035 17.0 15.4 6.2 2 2 3 5 5 5 2 Intermediate filament protein DUF4936 PF16290.5 EAX97247.1 - 0.35 11.6 4.9 3.8 8.3 0.1 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) Bromodomain PF00439.25 EAX97248.1 - 0.0013 18.8 0.8 0.0033 17.5 0.1 2.0 2 1 0 2 2 2 1 Bromodomain BET PF17035.5 EAX97248.1 - 0.0039 17.3 1.5 0.0073 16.4 0.3 2.1 1 1 1 2 2 2 1 Bromodomain extra-terminal - transcription regulation Cut8 PF08559.10 EAX97248.1 - 0.034 13.8 1.3 2.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Cut8, nuclear proteasome tether protein Fe_hyd_lg_C PF02906.14 EAX97250.1 - 5.4e-88 294.8 0.0 7.9e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EAX97250.1 - 1.8e-22 79.1 1.2 1.8e-22 79.1 1.2 2.0 2 0 0 2 2 2 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 EAX97250.1 - 1.4e-17 63.5 0.0 8.7e-17 61.0 0.0 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EAX97250.1 - 2e-08 33.7 10.6 2.6e-06 27.0 1.5 3.9 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EAX97250.1 - 4.1e-08 33.2 6.7 4.1e-08 33.2 6.7 3.0 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EAX97250.1 - 7e-07 29.7 19.0 1.3e-05 25.7 9.7 3.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAX97250.1 - 3.4e-06 27.1 8.5 3.4e-06 27.1 8.5 3.8 3 1 2 5 5 4 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAX97250.1 - 3.9e-06 26.7 8.9 0.00039 20.4 1.3 4.1 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EAX97250.1 - 2e-05 24.9 5.7 2e-05 24.9 5.7 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAX97250.1 - 0.00011 23.1 0.6 0.00011 23.1 0.6 3.8 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EAX97250.1 - 0.00022 21.3 7.6 0.0013 18.8 0.5 4.0 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAX97250.1 - 0.0063 16.9 2.4 0.0063 16.9 2.4 4.4 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_22 PF17179.4 EAX97250.1 - 0.058 14.2 18.1 0.23 12.3 0.3 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain NADH-G_4Fe-4S_3 PF10588.9 EAX97250.1 - 0.8 9.3 10.1 0.11 12.1 2.4 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_15 PF13459.6 EAX97250.1 - 1.5 9.6 16.0 0.87 10.4 1.2 3.6 4 0 0 4 4 4 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 EAX97250.1 - 2.1 8.9 27.6 0.48 11.0 12.0 3.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Rhomboid PF01694.22 EAX97251.1 - 6.4e-11 42.5 9.8 9.5e-11 41.9 9.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EAX97251.1 - 1.8e-05 25.2 2.6 1.8e-05 25.2 2.6 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF4306 PF14154.6 EAX97251.1 - 0.21 11.8 5.7 0.058 13.5 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) LRR_5 PF13306.6 EAX97252.1 - 7.4e-20 71.2 9.1 1.7e-13 50.7 0.3 3.0 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) MIG-14_Wnt-bd PF06664.12 EAX97253.1 - 1.4e-07 31.1 17.6 1.9e-06 27.3 17.7 2.3 2 1 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF1129 PF06570.11 EAX97253.1 - 0.00049 19.6 0.6 0.00049 19.6 0.6 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1129) V-ATPase_C PF03223.15 EAX97254.1 - 4.2e-72 243.6 0.1 8e-72 242.7 0.1 1.4 1 1 0 1 1 1 1 V-ATPase subunit C Trimer_CC PF08954.11 EAX97254.1 - 0.018 14.6 1.7 0.037 13.6 0.6 2.0 2 0 0 2 2 2 0 Trimerisation motif PSD4 PF07631.11 EAX97254.1 - 0.06 13.9 0.6 0.21 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) UPF0154 PF03672.13 EAX97255.1 - 0.064 13.3 0.2 7.2 6.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Chromo PF00385.24 EAX97256.1 - 1.2e-09 37.9 0.7 1.2e-09 37.9 0.7 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAX97256.1 - 3.7e-05 23.7 0.4 0.00068 19.7 0.1 2.3 2 0 0 2 2 2 1 Chromo shadow domain Tudor-knot PF11717.8 EAX97256.1 - 0.12 12.3 1.6 0.45 10.4 0.3 2.2 2 1 0 2 2 2 0 RNA binding activity-knot of a chromodomain TerB PF05099.13 EAX97257.1 - 0.061 13.3 0.8 2.2 8.2 0.3 2.3 1 1 0 2 2 2 0 Tellurite resistance protein TerB Filament PF00038.21 EAX97258.1 - 0.013 15.1 27.4 0.081 12.5 22.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein FPP PF05911.11 EAX97258.1 - 0.019 13.2 21.9 0.0038 15.5 18.2 1.8 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil IMD PF08397.11 EAX97258.1 - 0.14 11.5 15.1 0.092 12.1 12.8 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain Ax_dynein_light PF10211.9 EAX97258.1 - 0.95 9.4 27.6 3 7.7 19.9 3.4 1 1 1 2 2 2 0 Axonemal dynein light chain Ank_4 PF13637.6 EAX97259.1 - 1.8e-17 63.5 2.6 1.1e-10 41.8 0.4 2.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97259.1 - 1.7e-14 54.2 0.2 4e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97259.1 - 9.6e-12 44.0 0.8 3.4e-06 27.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX97259.1 - 1.5e-11 44.3 0.3 1.2e-07 31.9 0.3 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97259.1 - 1e-08 35.0 21.4 3.6e-07 30.1 0.4 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Ank PF00023.30 EAX97259.1 - 1.2e-07 31.9 0.0 7.7e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Nnf1 PF03980.14 EAX97260.1 - 0.0017 18.7 1.7 0.0017 18.7 1.7 2.7 2 1 1 3 3 3 1 Nnf1 ZapB PF06005.12 EAX97260.1 - 0.0079 16.6 17.2 0.16 12.5 5.4 3.0 2 1 1 3 3 3 2 Cell division protein ZapB DUF2729 PF10870.8 EAX97260.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DHR10 PF18595.1 EAX97260.1 - 0.048 13.7 16.7 1.5 8.9 1.4 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 EAX97260.1 - 0.052 13.6 14.9 1.1 9.4 5.6 3.2 2 1 0 2 2 2 0 bZIP transcription factor Sec34 PF04136.15 EAX97260.1 - 0.095 12.6 10.9 0.085 12.7 1.8 2.6 1 1 1 2 2 2 0 Sec34-like family APG6_N PF17675.1 EAX97260.1 - 0.14 12.6 23.2 0.33 11.5 16.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Uds1 PF15456.6 EAX97260.1 - 0.16 12.2 15.7 2.1 8.5 14.1 2.7 1 1 1 2 2 2 0 Up-regulated During Septation CENP-F_leu_zip PF10473.9 EAX97260.1 - 0.19 11.8 18.5 0.25 11.4 7.9 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EAX97260.1 - 0.2 12.3 13.6 2.9 8.6 0.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 EAX97260.1 - 0.31 12.0 18.5 0.044 14.7 11.5 2.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain betaPIX_CC PF16523.5 EAX97260.1 - 0.36 10.7 8.0 16 5.4 0.4 3.4 2 1 1 3 3 3 0 betaPIX coiled coil Lectin_N PF03954.14 EAX97260.1 - 0.44 10.3 5.9 0.19 11.4 2.1 2.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain UPF0242 PF06785.11 EAX97260.1 - 0.52 10.4 23.9 1.7 8.7 7.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 EAX97260.1 - 0.66 10.3 12.6 3.7 7.9 0.6 3.7 2 2 1 3 3 3 0 TSC-22/dip/bun family CCDC-167 PF15188.6 EAX97260.1 - 1 9.7 17.7 0.93 9.9 10.4 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 EAX97260.1 - 1.2 8.4 14.1 0.84 8.9 11.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 EAX97260.1 - 1.4 8.8 12.2 0.69 9.8 3.0 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4164 PF13747.6 EAX97260.1 - 1.5 9.1 12.8 6.7 7.1 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.12 EAX97260.1 - 1.7 9.3 14.1 4.2 8.0 3.5 2.8 1 1 2 3 3 3 0 SlyX GrpE PF01025.19 EAX97260.1 - 2.4 7.8 17.0 0.14 11.8 5.0 2.6 2 1 0 2 2 2 0 GrpE DivIC PF04977.15 EAX97260.1 - 2.8 7.8 28.1 1.1 9.1 2.1 4.6 3 2 2 5 5 5 0 Septum formation initiator DUF4140 PF13600.6 EAX97260.1 - 2.9 8.4 14.1 11 6.5 2.5 3.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.20 EAX97260.1 - 4.5 7.3 23.4 0.084 12.8 6.5 3.5 2 1 1 3 3 3 0 Prefoldin subunit THOC7 PF05615.13 EAX97260.1 - 4.7 7.5 21.1 0.53 10.6 13.9 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Retrotrans_gag PF03732.17 EAX97260.1 - 6.1 7.2 10.3 8.5 6.7 2.0 3.5 1 1 3 4 4 4 0 Retrotransposon gag protein Rho_Binding PF08912.11 EAX97260.1 - 8.8 7.2 20.4 1.1 10.2 7.1 3.0 3 1 0 3 3 3 0 Rho Binding FlaC_arch PF05377.11 EAX97260.1 - 8.8 6.8 7.9 7 7.1 2.1 3.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) E2F_CC-MB PF16421.5 EAX97260.1 - 9.2 6.7 16.3 0.37 11.2 2.0 3.1 3 1 0 3 3 3 0 E2F transcription factor CC-MB domain DP PF08781.10 EAX97260.1 - 9.3 6.2 15.3 1.9 8.4 2.4 2.6 3 0 0 3 3 3 0 Transcription factor DP EF-hand_1 PF00036.32 EAX97261.1 - 6.2e-28 94.2 6.0 1e-07 31.0 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX97261.1 - 2.7e-27 95.0 3.1 6.8e-15 55.3 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX97261.1 - 1.8e-22 77.3 2.5 4.2e-07 29.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAX97261.1 - 6.1e-20 70.8 7.3 2.6e-08 33.6 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX97261.1 - 1.4e-19 68.6 3.5 1.9e-06 27.1 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EAX97261.1 - 4.5e-15 55.7 0.1 4.1e-06 27.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX97261.1 - 4.2e-08 33.5 2.0 1.2e-05 25.5 0.3 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAX97261.1 - 1.4e-06 28.2 1.1 0.00042 20.2 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EAX97261.1 - 0.00017 21.6 2.0 0.00017 21.5 0.1 1.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) TerB PF05099.13 EAX97261.1 - 0.0046 16.9 0.2 0.026 14.5 0.0 2.2 2 1 1 3 3 3 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 EAX97261.1 - 0.011 16.1 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF2666 PF10869.8 EAX97261.1 - 0.016 15.4 0.6 2.9 8.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Caleosin PF05042.13 EAX97261.1 - 0.047 13.6 0.0 3 7.7 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 EAX97261.1 - 0.056 13.6 0.3 0.2 11.9 0.0 2.0 2 1 0 2 2 2 0 Dockerin type I domain Ank_2 PF12796.7 EAX97262.1 - 6.1e-43 145.3 8.3 1.2e-18 67.5 0.1 4.3 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97262.1 - 2.4e-32 110.9 3.0 9e-09 35.7 0.0 5.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97262.1 - 4.9e-28 96.8 1.8 1.8e-07 31.3 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97262.1 - 1.2e-26 89.8 1.4 0.0027 18.1 0.0 7.8 8 0 0 8 8 6 5 Ankyrin repeat Ank PF00023.30 EAX97262.1 - 5.5e-26 89.8 0.9 0.0052 17.2 0.0 7.9 8 0 0 8 8 7 4 Ankyrin repeat Spc7 PF08317.11 EAX97262.1 - 2.9e-06 26.4 6.8 5.5e-06 25.5 6.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HAUS5 PF14817.6 EAX97262.1 - 4.4e-06 25.8 1.8 6.2e-06 25.3 1.8 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 APG6_N PF17675.1 EAX97262.1 - 6.4e-06 26.7 9.1 6.4e-06 26.7 9.1 2.1 3 0 0 3 3 1 1 Apg6 coiled-coil region ATG16 PF08614.11 EAX97262.1 - 2.5e-05 24.6 8.1 4.5e-05 23.8 8.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EAX97262.1 - 2.7e-05 24.2 15.0 2.7e-05 24.2 15.0 2.3 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 EAX97262.1 - 2.7e-05 24.7 7.0 2.7e-05 24.7 7.0 1.7 2 0 0 2 2 1 1 Fez1 zf-C4H2 PF10146.9 EAX97262.1 - 2.8e-05 24.5 7.2 5.7e-05 23.5 7.2 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein DUF812 PF05667.11 EAX97262.1 - 3.8e-05 22.8 5.7 7.2e-05 21.9 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.6 EAX97262.1 - 4e-05 23.0 14.3 9.2e-05 21.9 14.3 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BicD PF09730.9 EAX97262.1 - 9.6e-05 21.0 4.6 0.00015 20.4 4.6 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Filament PF00038.21 EAX97262.1 - 0.0001 22.0 6.6 0.0002 21.0 6.6 1.4 1 0 0 1 1 1 1 Intermediate filament protein EzrA PF06160.12 EAX97262.1 - 0.0002 19.7 12.7 0.00031 19.1 12.7 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TSC22 PF01166.18 EAX97262.1 - 0.00023 21.4 16.3 0.0043 17.3 1.7 3.4 2 1 1 3 3 2 2 TSC-22/dip/bun family DUF641 PF04859.12 EAX97262.1 - 0.00027 21.3 5.1 0.00061 20.1 5.1 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Atg14 PF10186.9 EAX97262.1 - 0.00033 19.9 8.4 0.00048 19.3 8.4 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EAX97262.1 - 0.00068 19.7 5.3 0.0014 18.7 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MAD PF05557.13 EAX97262.1 - 0.00069 18.1 7.4 0.0011 17.5 7.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Golgin_A5 PF09787.9 EAX97262.1 - 0.00072 19.1 5.9 0.0012 18.4 5.9 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Paramyx_P_V_C PF03210.13 EAX97262.1 - 0.00079 19.3 1.1 0.18 11.6 0.9 2.7 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal HAP1_N PF04849.13 EAX97262.1 - 0.00083 18.6 4.7 0.0015 17.8 4.7 1.5 1 0 0 1 1 1 1 HAP1 N-terminal conserved region UPF0242 PF06785.11 EAX97262.1 - 0.00088 19.4 14.8 0.0012 19.0 13.7 1.7 1 1 1 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4472 PF14739.6 EAX97262.1 - 0.00093 19.9 8.0 0.0034 18.1 8.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) LPP PF04728.13 EAX97262.1 - 0.001 19.4 11.2 0.0088 16.4 1.4 3.7 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Laminin_I PF06008.14 EAX97262.1 - 0.0011 18.7 9.5 0.0011 18.7 9.5 1.6 2 0 0 2 2 1 1 Laminin Domain I Pox_A_type_inc PF04508.12 EAX97262.1 - 0.0013 18.5 1.0 3 7.8 0.1 3.9 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat DUF3450 PF11932.8 EAX97262.1 - 0.0013 18.1 7.4 0.0027 17.1 7.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HMMR_N PF15905.5 EAX97262.1 - 0.0015 18.1 11.5 0.003 17.1 11.5 1.5 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 EAX97262.1 - 0.0015 18.6 2.7 0.0015 18.6 2.7 3.4 3 1 2 5 5 3 1 bZIP transcription factor DUF724 PF05266.14 EAX97262.1 - 0.0016 18.3 9.7 0.0016 18.3 9.7 2.0 2 1 0 2 2 1 1 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 EAX97262.1 - 0.0038 17.9 9.9 0.0038 17.9 9.9 2.1 3 0 0 3 3 1 1 Occludin homology domain ADIP PF11559.8 EAX97262.1 - 0.0039 17.3 13.7 0.0039 17.3 13.7 2.3 2 1 0 2 2 1 1 Afadin- and alpha -actinin-Binding FPP PF05911.11 EAX97262.1 - 0.004 15.4 10.2 0.0065 14.7 10.2 1.4 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 EAX97262.1 - 0.0045 17.2 6.6 0.0045 17.2 6.6 1.7 2 0 0 2 2 1 1 JNK_SAPK-associated protein-1 T3SSipB PF16535.5 EAX97262.1 - 0.0048 17.4 2.4 0.0098 16.4 2.4 1.5 1 0 0 1 1 1 1 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 EAX97262.1 - 0.006 16.6 8.4 0.006 16.6 8.4 2.3 2 1 0 2 2 1 1 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EAX97262.1 - 0.007 16.0 3.4 0.0099 15.5 3.4 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit MscS_porin PF12795.7 EAX97262.1 - 0.0073 15.9 6.4 0.0073 15.9 6.4 1.8 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.8 EAX97262.1 - 0.0076 16.5 9.1 0.0076 16.5 9.1 2.2 2 1 1 3 3 2 2 TATA element modulatory factor 1 TATA binding Fungal_TACC PF12709.7 EAX97262.1 - 0.0094 16.4 16.3 0.39 11.2 3.9 3.5 1 1 2 3 3 3 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 EAX97262.1 - 0.0097 15.3 2.4 0.016 14.6 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DivIC PF04977.15 EAX97262.1 - 0.0099 15.6 16.0 0.14 12.0 4.8 3.1 2 1 1 3 3 2 2 Septum formation initiator Spectrin PF00435.21 EAX97262.1 - 0.011 16.2 2.8 0.043 14.3 1.2 2.5 1 1 1 2 2 2 0 Spectrin repeat CENP-F_leu_zip PF10473.9 EAX97262.1 - 0.012 15.6 11.5 0.039 14.0 11.6 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 EAX97262.1 - 0.012 15.5 6.6 0.022 14.7 6.6 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF3287 PF11690.8 EAX97262.1 - 0.013 15.3 0.5 0.057 13.1 0.2 2.2 1 1 0 2 2 1 0 Protein of unknown function (DUF3287) IFT57 PF10498.9 EAX97262.1 - 0.015 14.3 11.6 0.027 13.4 11.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Alpha-2-MRAP_C PF06401.11 EAX97262.1 - 0.017 15.1 9.4 0.043 13.8 9.4 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Tropomyosin_1 PF12718.7 EAX97262.1 - 0.019 15.2 3.7 0.019 15.2 3.7 2.9 2 1 1 3 3 2 0 Tropomyosin like Wzt_C PF14524.6 EAX97262.1 - 0.019 15.0 0.1 0.11 12.5 0.0 2.1 1 1 0 2 2 1 0 Wzt C-terminal domain DHR10 PF18595.1 EAX97262.1 - 0.02 15.0 8.7 0.12 12.4 2.4 2.6 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4200 PF13863.6 EAX97262.1 - 0.027 14.9 5.3 0.027 14.9 5.3 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) ZapB PF06005.12 EAX97262.1 - 0.034 14.6 20.5 0.12 12.9 8.3 2.9 2 1 1 3 3 2 0 Cell division protein ZapB SKA2 PF16740.5 EAX97262.1 - 0.036 13.8 5.7 0.33 10.7 0.2 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 HemX PF04375.14 EAX97262.1 - 0.037 13.3 6.6 0.069 12.4 6.5 1.5 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Lebercilin PF15619.6 EAX97262.1 - 0.046 13.4 10.1 0.43 10.2 6.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 EAX97262.1 - 0.047 14.1 14.3 0.45 10.9 1.7 3.4 1 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 EAX97262.1 - 0.049 13.7 1.2 0.049 13.7 1.2 3.0 2 1 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 JIP_LZII PF16471.5 EAX97262.1 - 0.055 13.6 5.6 3.6 7.8 0.2 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CREPT PF16566.5 EAX97262.1 - 0.08 13.1 8.5 0.27 11.4 2.3 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour KASH_CCD PF14662.6 EAX97262.1 - 0.085 12.7 18.7 0.016 15.1 14.4 1.9 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH YlqD PF11068.8 EAX97262.1 - 0.097 13.0 10.2 0.23 11.8 10.0 1.6 1 1 0 1 1 1 0 YlqD protein HsbA PF12296.8 EAX97262.1 - 0.11 12.9 1.7 2.1 8.8 0.3 2.5 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DASH_Hsk3 PF08227.11 EAX97262.1 - 0.12 12.8 1.4 5.9 7.3 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like KLRAQ PF10205.9 EAX97262.1 - 0.13 12.5 11.8 1.1 9.5 5.7 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein CLZ PF16526.5 EAX97262.1 - 0.15 12.5 4.2 2.9 8.3 0.7 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspA_IM30 PF04012.12 EAX97262.1 - 0.15 11.6 4.5 0.2 11.2 3.1 1.8 1 1 1 2 2 2 0 PspA/IM30 family V-SNARE PF05008.15 EAX97262.1 - 0.16 12.4 10.9 0.62 10.5 9.4 2.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Nup54 PF13874.6 EAX97262.1 - 0.18 11.9 4.3 1.6 8.9 4.4 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF5082 PF16888.5 EAX97262.1 - 0.18 12.1 17.3 0.35 11.1 9.1 2.9 1 1 3 4 4 3 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 EAX97262.1 - 0.19 11.0 11.5 0.32 10.2 10.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 EAX97262.1 - 0.2 12.1 3.7 3.6 8.1 0.3 2.6 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF489 PF04356.12 EAX97262.1 - 0.21 11.6 4.1 0.43 10.6 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Complex1_LYR_2 PF13233.6 EAX97262.1 - 0.21 12.4 2.9 0.92 10.3 2.8 2.2 2 0 0 2 2 1 0 Complex1_LYR-like PI3K_P85_iSH2 PF16454.5 EAX97262.1 - 0.23 11.0 13.5 1.9 8.1 12.4 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain USP8_interact PF08941.10 EAX97262.1 - 0.24 11.2 3.2 0.36 10.6 1.8 2.1 2 0 0 2 2 1 0 USP8 interacting FapA PF03961.13 EAX97262.1 - 0.26 9.8 15.6 0.48 9.0 14.4 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 EAX97262.1 - 0.26 11.5 5.1 0.57 10.5 3.6 2.2 1 1 1 2 2 1 0 ABC transporter C-terminal domain She9_MDM33 PF05546.11 EAX97262.1 - 0.27 11.0 9.0 0.039 13.8 4.9 1.7 2 0 0 2 2 1 0 She9 / Mdm33 family CALCOCO1 PF07888.11 EAX97262.1 - 0.31 9.9 9.4 0.55 9.0 6.2 1.9 2 1 0 2 2 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BAR_3 PF16746.5 EAX97262.1 - 0.33 10.6 14.8 0.5 10.0 4.5 2.5 1 1 1 2 2 2 0 BAR domain of APPL family DUF2443 PF10398.9 EAX97262.1 - 0.33 11.0 10.1 4.5 7.4 0.2 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2443) Tnp_22_trimer PF17489.2 EAX97262.1 - 0.37 10.8 2.4 0.63 10.1 0.7 2.4 2 0 0 2 2 1 0 L1 transposable element trimerization domain DUF3848 PF12959.7 EAX97262.1 - 0.37 10.9 6.0 0.55 10.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) IFT20 PF14931.6 EAX97262.1 - 0.4 10.8 14.8 0.1 12.7 11.1 2.0 2 0 0 2 2 1 0 Intraflagellar transport complex B, subunit 20 Uds1 PF15456.6 EAX97262.1 - 0.44 10.7 4.2 6.3 7.0 4.1 2.3 1 1 0 1 1 1 0 Up-regulated During Septation Ax_dynein_light PF10211.9 EAX97262.1 - 0.46 10.4 14.4 1.5 8.7 14.4 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain CorA PF01544.18 EAX97262.1 - 0.46 9.7 9.2 2 7.7 0.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PI_PP_I PF18363.1 EAX97262.1 - 0.51 10.5 6.7 7.3 6.9 6.5 2.6 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain CENP-H PF05837.12 EAX97262.1 - 0.54 10.7 10.3 4.1 7.8 8.7 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 EAX97262.1 - 0.6 10.0 12.0 0.039 13.8 3.3 2.9 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 EAX97262.1 - 0.73 10.1 18.4 0.45 10.8 12.4 2.9 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 EAX97262.1 - 0.76 10.5 5.8 0.53 11.0 3.3 2.1 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) TolA_bind_tri PF16331.5 EAX97262.1 - 0.85 9.7 6.8 1.9 8.7 3.3 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Tup_N PF08581.10 EAX97262.1 - 0.92 9.9 14.2 0.78 10.1 9.7 3.1 2 1 1 3 3 2 0 Tup N-terminal BLOC1_2 PF10046.9 EAX97262.1 - 0.94 9.8 19.2 1.4 9.2 4.4 3.9 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.19 EAX97262.1 - 1 9.0 21.2 0.51 10.0 3.1 3.4 2 1 2 4 4 3 0 GrpE Prefoldin PF02996.17 EAX97262.1 - 1.1 9.2 12.0 1.3 8.9 3.3 3.2 1 1 1 3 3 3 0 Prefoldin subunit LOH1CR12 PF10158.9 EAX97262.1 - 1.2 9.2 7.9 4 7.5 6.6 2.2 1 1 1 2 2 2 0 Tumour suppressor protein NPV_P10 PF05531.12 EAX97262.1 - 1.3 9.6 7.2 4.8 7.7 0.8 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EAX97262.1 - 1.5 8.9 11.1 4.1 7.4 10.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 EAX97262.1 - 1.5 9.2 16.0 1.1 9.6 11.7 2.6 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LMBR1 PF04791.16 EAX97262.1 - 1.5 7.6 7.0 2.3 7.0 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CC2-LZ PF16516.5 EAX97262.1 - 1.6 9.2 10.2 7 7.1 2.4 2.6 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Snapin_Pallidin PF14712.6 EAX97262.1 - 1.7 9.1 12.0 1.3 9.5 1.9 3.1 1 1 2 3 3 3 0 Snapin/Pallidin Cnn_1N PF07989.11 EAX97262.1 - 1.8 8.8 17.1 0.42 10.8 11.7 2.8 2 1 0 2 2 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 EAX97262.1 - 2.1 9.0 14.9 4.1 8.1 11.1 3.0 2 1 0 2 2 1 0 Initiation control protein YabA DUF2400 PF09674.10 EAX97262.1 - 2.1 8.3 6.5 3.4 7.6 5.4 1.9 1 1 1 2 2 1 0 Protein of unknown function (DUF2400) SlyX PF04102.12 EAX97262.1 - 2.2 9.0 3.8 18 6.0 0.4 2.4 1 1 1 2 2 2 0 SlyX SOGA PF11365.8 EAX97262.1 - 2.3 9.4 7.6 10 7.3 7.0 2.5 1 1 0 1 1 1 0 Protein SOGA DUF948 PF06103.11 EAX97262.1 - 2.5 8.4 4.0 19 5.6 4.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 EAX97262.1 - 2.6 8.3 12.5 1 9.6 8.9 2.2 2 1 1 3 3 2 0 Flagellar FliJ protein Csm1_N PF18504.1 EAX97262.1 - 2.7 8.4 10.8 3.3 8.1 3.2 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Nnf1 PF03980.14 EAX97262.1 - 2.8 8.4 9.0 1.1 9.7 0.3 2.7 2 1 1 3 3 2 0 Nnf1 DUF2935 PF11155.8 EAX97262.1 - 3 8.2 10.1 1.3e+02 2.9 9.9 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF1640 PF07798.11 EAX97262.1 - 3.6 7.6 11.5 13 5.8 11.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 EAX97262.1 - 3.8 7.1 9.1 5.7 6.5 4.3 2.2 1 1 1 2 2 2 0 fzo-like conserved region COG2 PF06148.11 EAX97262.1 - 4.7 7.3 9.6 1.5 8.9 1.5 2.8 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BST2 PF16716.5 EAX97262.1 - 5.3 7.7 15.8 0.24 12.0 1.7 3.2 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 DUF4446 PF14584.6 EAX97262.1 - 5.8 6.9 12.0 4 7.4 2.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) THOC7 PF05615.13 EAX97262.1 - 6.6 7.0 14.1 1.2 9.4 9.5 2.2 2 1 0 2 2 1 0 Tho complex subunit 7 TMF_DNA_bd PF12329.8 EAX97262.1 - 8 6.5 29.5 0.052 13.5 7.4 4.0 3 1 2 5 5 4 0 TATA element modulatory factor 1 DNA binding DUF4094 PF13334.6 EAX97262.1 - 8.1 6.9 12.9 0.5 10.8 2.2 3.7 3 2 1 4 4 2 0 Domain of unknown function (DUF4094) bZIP_2 PF07716.15 EAX97262.1 - 8.9 6.5 18.0 0.078 13.1 1.2 3.7 3 1 1 4 4 3 0 Basic region leucine zipper DUF4201 PF13870.6 EAX97262.1 - 9.1 6.0 22.0 0.66 9.7 15.7 2.3 2 1 0 2 2 1 0 Domain of unknown function (DUF4201) DUF16 PF01519.16 EAX97262.1 - 9.1 6.8 16.0 6.7 7.3 8.8 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1992 PF09350.10 EAX97263.1 - 0.013 15.7 2.6 0.033 14.3 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Copine PF07002.16 EAX97264.1 - 4.5e-71 238.8 0.0 7.9e-71 238.0 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 EAX97264.1 - 5.8e-14 52.2 0.0 7e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EAX97264.1 - 5.5e-05 23.4 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 vWA found in TerF C terminus LRS4 PF10422.9 EAX97264.1 - 0.055 13.0 0.5 0.091 12.3 0.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMP PF05017.14 EAX97266.1 - 0.016 15.6 5.5 2.9 8.9 0.3 3.4 3 1 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAX97267.1 - 8.4e-12 45.5 0.9 0.00045 20.7 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97267.1 - 5.4e-10 38.6 0.3 1.6 9.5 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX97267.1 - 6.3e-06 26.6 0.3 2.6 8.7 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97267.1 - 0.0002 21.6 0.0 1.4 9.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97267.1 - 0.00021 21.6 0.2 1.6 9.3 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat DHHC PF01529.20 EAX97268.1 - 8.7e-20 71.2 6.0 8.7e-20 71.2 6.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2593 PF10767.9 EAX97268.1 - 3.2 7.8 9.8 0.16 12.0 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2593) Pkinase PF00069.25 EAX97269.1 - 9.2e-57 192.4 0.0 1.2e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97269.1 - 5.9e-30 104.4 0.0 7.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97269.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX97269.1 - 0.00054 19.1 0.0 0.00088 18.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EAX97269.1 - 0.0013 17.7 0.8 0.13 11.1 0.0 2.7 2 1 1 3 3 3 2 Haspin like kinase domain Clathrin PF00637.20 EAX97269.1 - 0.0084 16.0 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Kdo PF06293.14 EAX97269.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M8 PF01457.16 EAX97270.1 - 1.1e-19 70.5 0.0 1.5e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin TMEM154 PF15102.6 EAX97270.1 - 0.0096 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Myb_DNA-binding PF00249.31 EAX97274.1 - 4.4e-15 55.6 0.1 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97274.1 - 1e-10 41.7 0.0 1.3e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Corona_S2 PF01601.16 EAX97275.1 - 6.5 5.1 18.7 9.9 4.5 18.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RhoGEF PF00621.20 EAX97276.1 - 7.3e-37 127.4 0.6 7.3e-37 127.4 0.6 1.9 2 0 0 2 2 2 1 RhoGEF domain Kelch_1 PF01344.25 EAX97276.1 - 2.6e-26 90.9 0.0 1.1e-07 31.3 0.2 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EAX97276.1 - 5.8e-25 87.0 0.0 4.5e-08 33.2 0.0 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EAX97276.1 - 8.6e-23 80.1 0.8 2.4e-07 30.6 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX97276.1 - 1.3e-22 79.3 1.1 5.1e-05 23.4 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EAX97276.1 - 2.7e-21 75.1 0.1 1.9e-07 30.9 0.1 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EAX97276.1 - 2.8e-17 61.9 2.6 1.9e-05 24.4 0.5 4.9 4 0 0 4 4 4 4 Kelch motif Glyoxal_oxid_N PF07250.11 EAX97276.1 - 0.021 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Eaf7 PF07904.13 EAX97276.1 - 0.082 13.3 0.1 0.082 13.3 0.1 2.3 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 COG5 PF10392.9 EAX97277.1 - 0.0071 16.5 3.8 0.0071 16.5 3.8 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 bZIP_C PF12498.8 EAX97277.1 - 0.0096 16.9 0.2 0.035 15.1 0.2 1.9 1 0 0 1 1 1 1 Basic leucine-zipper C terminal Transposase_mut PF00872.18 EAX97277.1 - 0.034 13.0 6.1 0.037 12.9 0.6 2.3 2 0 0 2 2 2 0 Transposase, Mutator family KRAP_IP3R_bind PF14722.6 EAX97277.1 - 0.29 10.9 6.7 0.06 13.1 1.5 2.4 2 1 1 3 3 3 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain ThylakoidFormat PF11264.8 EAX97277.1 - 1.2 8.7 12.9 0.12 12.0 6.6 2.3 2 1 0 2 2 2 0 Thylakoid formation protein ADIP PF11559.8 EAX97277.1 - 2.2 8.4 27.3 0.1 12.7 5.1 4.4 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 EAX97277.1 - 3 8.0 26.4 0.83 9.8 8.2 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EAX97277.1 - 7 5.9 16.5 0.52 9.6 3.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Arginase PF00491.21 EAX97278.1 - 4.8e-20 72.2 0.0 6.1e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF3530 PF12048.8 EAX97278.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MBOAT PF03062.19 EAX97279.1 - 1.2e-12 47.8 21.4 1.5e-12 47.6 19.1 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family C2 PF00168.30 EAX97280.1 - 0.0009 19.5 0.0 0.0018 18.6 0.0 1.4 1 1 0 1 1 1 1 C2 domain Pkinase_Tyr PF07714.17 EAX97283.1 - 2.9e-63 213.6 0.0 6.1e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX97283.1 - 1.5e-61 208.1 0.0 2.5e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EAX97283.1 - 0.0048 15.9 0.8 0.15 11.0 0.8 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX97283.1 - 0.045 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm44 PF15571.6 EAX97283.1 - 1.1 9.5 4.3 4.3 7.6 0.1 3.1 3 0 0 3 3 3 0 Immunity protein 44 DUF5365 PF17326.2 EAX97285.1 - 0.029 14.8 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAX97285.1 - 0.04 14.2 0.4 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 PWI domain Phage_TTP_1 PF04630.12 EAX97287.1 - 0.028 13.7 0.2 0.033 13.5 0.2 1.2 1 0 0 1 1 1 0 Phage tail tube protein Adaptin_N PF01602.20 EAX97288.1 - 2e-78 264.3 7.5 2.7e-78 263.8 7.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX97288.1 - 9.2e-06 25.8 1.7 0.0081 16.2 0.0 3.9 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Pox_Ag35 PF03286.14 EAX97288.1 - 0.026 14.3 5.1 0.057 13.2 5.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RTP1_C1 PF10363.9 EAX97288.1 - 0.032 14.4 0.2 0.46 10.7 0.0 3.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 B2-adapt-app_C PF09066.10 EAX97288.1 - 0.093 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Neuregulin PF02158.15 EAX97288.1 - 0.13 11.6 2.9 0.25 10.7 2.9 1.3 1 0 0 1 1 1 0 Neuregulin intracellular region CNDH2_C PF16858.5 EAX97288.1 - 0.15 11.9 5.8 0.25 11.2 5.8 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AIM3 PF17096.5 EAX97288.1 - 2 9.4 4.9 3.7 8.5 4.9 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 FAM176 PF14851.6 EAX97288.1 - 3.5 7.3 5.7 9 6.0 5.7 1.6 1 0 0 1 1 1 0 FAM176 family Ank_4 PF13637.6 EAX97289.1 - 1.1e-53 179.0 14.9 8.1e-14 51.8 0.2 8.6 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97289.1 - 3.2e-49 165.4 17.9 4.5e-17 62.4 1.9 5.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97289.1 - 8.8e-43 142.9 11.8 2.6e-07 30.8 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX97289.1 - 1e-36 120.8 19.2 1.1e-05 25.4 0.1 10.1 10 1 1 11 11 11 7 Ankyrin repeat DUF3447 PF11929.8 EAX97289.1 - 2.4e-36 123.5 3.6 2.4e-36 123.5 3.6 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX97289.1 - 3.9e-33 113.1 6.5 1.7e-09 37.7 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) DUF1512 PF07431.12 EAX97289.1 - 0.029 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) ATP13 PF12921.7 EAX97289.1 - 0.36 10.7 2.8 0.52 10.2 0.5 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase expression PSP PF04046.16 EAX97290.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97291.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX97293.1 - 3.4e-51 171.2 37.2 4.7e-33 113.0 14.6 5.0 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX97293.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2362 PF10154.9 EAX97294.1 - 0.0011 18.1 2.6 0.0015 17.5 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF2053 PF09767.9 EAX97296.1 - 8e-06 26.1 11.8 8e-06 26.1 11.8 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) CDC73_C PF05179.14 EAX97297.1 - 3.8e-31 107.9 3.8 9.7e-31 106.6 3.8 1.7 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EAX97297.1 - 0.00025 20.5 0.5 0.00038 19.9 0.5 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal DUF3854 PF12965.7 EAX97297.1 - 0.034 14.1 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) PLDc_3 PF13918.6 EAX97297.1 - 0.093 12.4 0.5 0.39 10.3 0.2 2.0 1 1 1 2 2 2 0 PLD-like domain TAF6_C PF07571.13 EAX97298.1 - 3.1e-09 37.0 0.4 2.1e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Herpes_glycoH_C PF17488.2 EAX97299.1 - 0.01 15.6 2.2 0.023 14.5 2.2 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain UL42 PF17638.2 EAX97299.1 - 0.18 11.8 0.9 2 8.4 0.1 2.3 2 0 0 2 2 2 0 HCMV UL42 Pkinase PF00069.25 EAX97300.1 - 9.2e-63 212.1 0.0 1.7e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97300.1 - 9.8e-45 152.8 0.0 1.6e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX97300.1 - 7.7e-05 21.6 1.0 0.00022 20.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EAX97300.1 - 0.00018 20.9 0.0 0.00063 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like bZIP_1 PF00170.21 EAX97300.1 - 0.00038 20.5 2.8 0.00086 19.4 2.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor NRBF2 PF08961.10 EAX97300.1 - 0.0027 17.4 2.3 0.0049 16.5 1.4 2.0 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator DUF812 PF05667.11 EAX97300.1 - 0.0046 15.9 4.7 0.0058 15.6 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Fes1 PF08609.10 EAX97300.1 - 0.011 16.5 5.7 0.011 16.5 5.7 2.0 2 0 0 2 2 1 0 Nucleotide exchange factor Fes1 ZapB PF06005.12 EAX97300.1 - 0.012 16.1 2.1 0.012 16.1 2.1 1.9 2 0 0 2 2 1 0 Cell division protein ZapB FlaC_arch PF05377.11 EAX97300.1 - 0.013 15.9 1.7 0.032 14.6 1.7 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Haspin_kinase PF12330.8 EAX97300.1 - 0.022 13.7 0.2 0.022 13.7 0.2 2.0 2 1 0 2 2 2 0 Haspin like kinase domain HALZ PF02183.18 EAX97300.1 - 0.043 14.0 1.2 0.098 12.9 1.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 EAX97300.1 - 0.054 13.3 4.4 0.044 13.6 2.1 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 EAX97300.1 - 0.11 12.6 0.8 0.22 11.6 0.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 EAX97300.1 - 0.14 12.2 8.0 0.037 14.1 4.4 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.8 EAX97300.1 - 0.37 10.4 7.3 0.69 9.5 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3450 PF11932.8 EAX97300.1 - 0.57 9.4 10.7 0.94 8.7 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CLZ PF16526.5 EAX97300.1 - 1.2 9.6 4.8 25 5.3 1.9 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nucleo_P87 PF07267.11 EAX97300.1 - 1.9 7.2 11.3 2.8 6.7 11.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hamartin PF04388.12 EAX97300.1 - 3.2 6.3 11.9 3.8 6.1 11.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3123 PF11321.8 EAX97300.1 - 4.5 8.0 15.0 0.14 12.9 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) UPF0242 PF06785.11 EAX97300.1 - 7.1 6.7 9.3 24 4.9 9.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LRR_6 PF13516.6 EAX97301.1 - 8.2e-09 34.8 29.1 0.062 13.4 0.1 10.4 10 0 0 10 10 10 4 Leucine Rich repeat DUF4515 PF14988.6 EAX97301.1 - 0.0035 17.2 29.9 0.0052 16.6 17.6 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) LRR_1 PF00560.33 EAX97301.1 - 0.012 16.1 24.7 46 5.1 0.1 10.1 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.7 EAX97301.1 - 0.031 14.7 36.4 0.67 10.5 0.5 8.0 4 3 7 11 11 11 0 Leucine Rich repeats (2 copies) DUF3371 PF11851.8 EAX97301.1 - 0.06 14.5 1.2 0.35 12.0 1.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3371) HMMR_N PF15905.5 EAX97301.1 - 0.091 12.2 30.7 0.16 11.4 30.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ALMT PF11744.8 EAX97301.1 - 0.17 10.7 15.0 0.28 10.0 15.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TolA_bind_tri PF16331.5 EAX97301.1 - 0.29 11.3 8.6 0.2 11.7 4.1 2.8 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF3584 PF12128.8 EAX97301.1 - 0.31 8.5 25.5 0.45 8.0 25.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 EAX97301.1 - 2.3 8.4 22.6 0.92 9.7 18.0 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EAX97301.1 - 3.9 7.5 18.5 1.9 8.5 6.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EAX97301.1 - 5.2 7.6 23.6 6.7 7.2 15.3 2.5 1 1 1 2 2 2 0 Spectrin repeat Lectin_N PF03954.14 EAX97301.1 - 5.2 6.8 12.0 35 4.1 12.0 2.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 EAX97301.1 - 7.6 6.6 18.5 2.3 8.3 6.7 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3086 PF11285.8 EAX97301.1 - 9.1 5.3 12.6 20 4.2 12.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) TerD PF02342.18 EAX97302.1 - 1.2e-15 57.5 0.0 6.8e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 TerD domain C2 PF00168.30 EAX97302.1 - 1.1e-13 51.3 0.1 3.1e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain LRR_5 PF13306.6 EAX97303.1 - 3e-107 353.7 80.0 1.9e-27 95.7 1.7 6.4 3 1 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) Pentapeptide_4 PF13599.6 EAX97303.1 - 0.08 13.1 9.8 4.8 7.4 0.8 4.7 5 2 1 6 6 6 0 Pentapeptide repeats (9 copies) Recep_L_domain PF01030.24 EAX97303.1 - 0.086 13.0 0.2 0.086 13.0 0.2 3.5 3 1 0 3 3 3 0 Receptor L domain Acetyltransf_1 PF00583.25 EAX97304.1 - 8.1e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAX97304.1 - 2.9e-05 24.4 0.0 4.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX97304.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EAX97304.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RAWUL PF16207.5 EAX97304.1 - 0.035 14.8 0.2 0.59 10.8 0.0 2.3 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DDE_Tnp_1_assoc PF13808.6 EAX97304.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-associated MMR_HSR1_Xtn PF16897.5 EAX97305.1 - 3.5e-26 91.3 0.2 9e-26 90.0 0.2 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EAX97305.1 - 5e-23 80.9 0.1 8.7e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EAX97305.1 - 2.1e-20 72.9 0.0 4.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAX97305.1 - 5.7e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAX97305.1 - 0.0014 18.7 0.1 0.17 12.0 0.0 2.4 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EAX97305.1 - 0.11 12.4 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase PACT_coil_coil PF10495.9 EAX97306.1 - 0.16 12.6 4.3 1.6 9.4 1.5 2.5 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein ALMT PF11744.8 EAX97306.1 - 4.8 5.9 12.4 6 5.6 9.4 1.9 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF16 PF01519.16 EAX97306.1 - 7.2 7.2 9.9 18 5.8 7.8 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ank_2 PF12796.7 EAX97307.1 - 7e-05 23.3 0.0 0.0034 17.9 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX97307.1 - 0.0016 18.3 0.6 0.0016 18.3 0.6 2.2 1 1 2 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX97307.1 - 0.0018 18.6 0.0 2 9.2 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX97307.1 - 0.003 18.1 0.0 1.1 9.9 0.0 3.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) APC_15aa PF05972.11 EAX97307.1 - 0.033 14.4 0.3 1 9.8 0.2 2.6 2 0 0 2 2 2 0 APC 15 residue motif Adeno_E3_CR2 PF02439.15 EAX97308.1 - 0.0019 17.9 1.9 0.0039 16.9 1.9 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 EAX97308.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EAX97308.1 - 0.0059 16.7 1.2 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Podoplanin Glycophorin_A PF01102.18 EAX97308.1 - 0.014 15.7 0.8 0.041 14.1 0.0 2.3 3 0 0 3 3 3 0 Glycophorin A Syndecan PF01034.20 EAX97308.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EAX97308.1 - 0.031 14.2 0.1 0.031 14.2 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family Orf78 PF06024.12 EAX97308.1 - 0.04 14.2 0.0 0.62 10.4 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) MtrF PF09472.10 EAX97308.1 - 0.19 11.1 3.5 0.36 10.3 3.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 EAX97308.1 - 0.9 9.0 5.7 2.3 7.7 5.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TQ PF18202.1 EAX97308.1 - 1.4 9.5 8.3 1.2 9.7 4.1 2.6 1 1 1 2 2 2 0 T-Q ester bond containing domain ANAPC4_WD40 PF12894.7 EAX97309.1 - 0.004 17.4 0.0 11 6.3 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_4 PF12763.7 EAX97310.1 - 0.76 9.8 4.9 0.55 10.2 0.1 3.0 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Cyclin_N PF00134.23 EAX97311.1 - 4e-30 104.2 0.9 6.5e-29 100.2 0.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Pkinase PF00069.25 EAX97312.1 - 1.1e-44 152.8 0.0 1.4e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97312.1 - 1.1e-16 60.9 0.1 1.9e-14 53.6 0.1 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EAX97312.1 - 0.00036 20.5 0.1 0.00055 19.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX97312.1 - 0.0028 17.0 0.3 0.005 16.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX97312.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_5 PF13306.6 EAX97313.1 - 3.5e-135 444.1 83.4 4.8e-26 91.2 4.5 8.2 1 1 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97313.1 - 5.8e-29 99.7 2.5 6e-05 22.7 0.0 10.6 10 2 1 12 12 12 8 Leucine rich repeat LRR_4 PF12799.7 EAX97313.1 - 0.00016 22.0 13.1 2.1 8.9 0.1 9.5 8 4 3 12 12 12 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EAX97314.1 - 7.5e-68 228.7 2.3 1.2e-67 228.0 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97314.1 - 6.3e-49 166.6 0.0 1.7e-48 165.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97314.1 - 2.9e-05 23.6 0.0 2.9e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EAX97314.1 - 0.0022 17.0 0.1 0.0072 15.3 0.1 1.8 1 0 0 1 1 1 1 Haspin like kinase domain FliN_N PF16973.5 EAX97314.1 - 0.59 10.0 4.2 1.3 8.9 1.8 3.0 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal zf-C2HC_2 PF13913.6 EAX97314.1 - 0.61 10.1 5.5 1e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF3584 PF12128.8 EAX97317.1 - 0.096 10.2 59.3 0.13 9.7 59.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4279 PF14106.6 EAX97317.1 - 0.14 12.4 14.1 0.31 11.2 0.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) Fez1 PF06818.15 EAX97317.1 - 0.2 12.1 66.1 0.042 14.3 30.7 2.5 1 1 1 2 2 2 0 Fez1 Metallophos PF00149.28 EAX97319.1 - 1.9e-31 110.2 1.0 2.6e-31 109.7 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX97319.1 - 0.0004 20.6 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3209 PF11483.8 EAX97319.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) LRR_4 PF12799.7 EAX97320.1 - 1.1e-07 32.1 8.0 4.2e-06 27.0 0.4 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX97320.1 - 5.7e-05 22.8 0.2 5.7e-05 22.8 0.2 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 EAX97320.1 - 0.014 14.9 0.5 0.027 14.0 0.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 EAX97320.1 - 0.037 14.6 2.4 24 6.0 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EAX97320.1 - 0.35 11.0 0.0 0.35 11.0 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat PK_C PF02887.16 EAX97321.1 - 0.026 14.7 6.8 46 4.3 4.9 4.3 2 2 0 2 2 2 0 Pyruvate kinase, alpha/beta domain WW_FCH_linker PF16623.5 EAX97321.1 - 3.2 8.6 23.2 17 6.2 1.2 5.9 1 1 4 5 5 5 0 Unstructured linker region between on GAS7 protein KAAG1 PF15354.6 EAX97321.1 - 9 6.9 15.7 23 5.6 1.0 3.6 1 1 2 4 4 4 0 Kidney-associated antigen 1 DUF3447 PF11929.8 EAX97322.1 - 4.6e-41 138.6 5.9 4.6e-41 138.6 5.9 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97322.1 - 1.3e-25 89.8 7.5 9.7e-16 58.1 2.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97322.1 - 3.9e-23 80.8 3.7 3.6e-08 33.5 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX97322.1 - 3.6e-21 75.3 2.5 1.5e-07 31.8 0.1 6.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97322.1 - 1.2e-19 68.3 5.8 1.1e-06 28.5 0.1 6.5 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX97322.1 - 1.8e-12 47.2 1.7 0.00041 20.6 0.1 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DUF1128 PF06569.11 EAX97322.1 - 0.22 11.5 2.0 3.2 7.8 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) DUF4442 PF14539.6 EAX97322.1 - 0.96 9.6 3.1 13 5.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) Dzip-like_N PF13815.6 EAX97323.1 - 1.5e-08 34.6 1.8 1.5e-08 34.6 1.8 2.2 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ARS2 PF04959.13 EAX97323.1 - 0.00012 22.5 0.6 0.00012 22.5 0.6 2.9 2 0 0 2 2 2 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 EAX97323.1 - 0.0091 16.8 0.3 0.021 15.7 0.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAX97323.1 - 0.027 14.8 0.9 0.071 13.4 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 EAX97323.1 - 0.045 13.6 2.4 0.078 12.8 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 EAX97323.1 - 0.045 14.2 0.4 0.11 13.0 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 EAX97323.1 - 0.21 12.0 0.4 0.45 11.0 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Cystatin PF00031.21 EAX97324.1 - 1.8 8.9 4.7 1 9.7 0.1 2.7 3 0 0 3 3 3 0 Cystatin domain UN_NPL4 PF11543.8 EAX97324.1 - 5 7.7 6.4 10 6.7 1.7 2.9 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 DUF3919 PF13057.6 EAX97325.1 - 0.0062 16.2 0.4 0.0092 15.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3919) Syndecan PF01034.20 EAX97326.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.9 2 0 0 2 2 2 0 Syndecan domain EphA2_TM PF14575.6 EAX97326.1 - 4.6 8.2 6.2 11 7.0 6.2 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PrmA PF06325.13 EAX97327.1 - 4e-06 26.4 0.0 6.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EAX97327.1 - 0.00017 22.2 0.0 0.00033 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAX97327.1 - 0.00066 18.7 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EAX97327.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 EAX97327.1 - 0.0022 18.6 0.0 0.0041 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAX97327.1 - 0.0035 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EAX97327.1 - 0.0062 16.4 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EAX97327.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 EAX97327.1 - 0.036 13.5 0.1 0.098 12.1 0.1 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB PRMT5_C PF17286.2 EAX97327.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 EAX97327.1 - 0.065 14.0 0.0 0.2 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ox_reductase_C PF08635.10 EAX97327.1 - 0.078 12.6 0.4 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative oxidoreductase C terminal domain GidB PF02527.15 EAX97327.1 - 0.15 11.4 0.0 0.39 10.0 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G GPS2_interact PF15784.5 EAX97329.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97329.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX97330.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX97330.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX97331.1 - 0.082 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX97331.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX97332.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX97332.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAX97333.1 - 0.08 12.9 0.4 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX97333.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX97334.1 - 4.7e-29 101.6 13.5 2e-28 99.5 13.5 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral HECT PF00632.25 EAX97337.1 - 2.3e-33 116.0 1.0 1.2e-32 113.7 0.1 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CLU_N PF15044.6 EAX97337.1 - 2.1 8.8 5.9 0.71 10.3 0.2 3.1 3 0 0 3 3 3 0 Mitochondrial function, CLU-N-term DUF1548 PF07579.11 EAX97337.1 - 8.4 6.7 7.9 1.2 9.5 1.3 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) Flavodoxin_2 PF02525.17 EAX97338.1 - 3.1e-30 105.4 0.0 3.7e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX97338.1 - 2.6e-09 37.0 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PSP PF04046.16 EAX97339.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97340.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX97342.1 - 2e-05 24.5 1.0 2e-05 24.5 1.0 3.9 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAX97342.1 - 0.023 14.5 7.0 0.028 14.2 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAX97342.1 - 0.056 13.2 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX97342.1 - 0.074 12.8 0.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4795 PF16043.5 EAX97342.1 - 0.25 10.9 13.0 0.058 13.0 5.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX97344.1 - 1.8e-135 450.0 10.1 2.8e-135 449.4 10.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX97344.1 - 0.053 13.9 0.6 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX97344.1 - 0.24 11.9 8.8 0.77 10.3 0.5 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX97345.1 - 1.1e-40 138.0 0.8 1.8e-40 137.3 0.2 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX97345.1 - 0.025 15.2 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family Ank_2 PF12796.7 EAX97346.1 - 2.6e-37 127.2 0.6 7.8e-17 61.6 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97346.1 - 2.1e-28 98.0 6.9 3.1e-09 36.9 0.1 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97346.1 - 2.8e-27 94.7 2.5 1.9e-08 34.7 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97346.1 - 1.4e-22 77.3 4.6 3.7e-05 23.8 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX97346.1 - 2.6e-21 75.1 2.3 5.2e-05 23.5 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat RTBV_P46 PF06216.11 EAX97347.1 - 0.00088 18.3 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein DUF3447 PF11929.8 EAX97348.1 - 2.7e-39 133.0 5.8 2.7e-39 133.0 5.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX97348.1 - 1.5e-31 108.3 5.0 2e-09 37.8 0.0 6.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97348.1 - 1.2e-30 105.9 6.4 6.2e-17 62.0 1.6 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97348.1 - 1e-24 85.8 5.7 9.3e-08 32.2 0.3 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAX97348.1 - 8.1e-22 75.0 5.7 1.2e-05 25.3 0.1 6.9 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX97348.1 - 2e-20 72.6 6.0 2.6e-09 37.2 0.4 4.3 2 2 2 5 5 5 3 Ankyrin repeats (many copies) CdhD PF03599.16 EAX97348.1 - 0.022 13.5 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Proteasome PF00227.26 EAX97349.1 - 1.8e-52 177.6 0.1 2.4e-52 177.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAX97349.1 - 6e-14 51.4 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Exo_endo_phos PF03372.23 EAX97351.1 - 0.003 17.1 0.0 0.0075 15.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IBD PF10416.9 EAX97353.1 - 5.1e-40 136.5 0.1 6.9e-40 136.0 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4106 PF13388.6 EAX97354.1 - 5.1e-261 866.0 19.9 5.1e-261 866.0 19.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX97354.1 - 0.075 13.3 2.3 1.5 9.2 0.1 3.2 3 0 0 3 3 3 0 Kidney androgen-regulated ArsC PF03960.15 EAX97354.1 - 0.35 10.9 1.9 1 9.4 0.1 2.8 3 0 0 3 3 3 0 ArsC family Autophagy_N PF03986.13 EAX97355.1 - 0.16 11.9 0.1 1.8 8.5 0.1 2.4 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain GyrI-like PF06445.15 EAX97356.1 - 3.2e-08 34.0 0.1 8.7e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 GyrI-like small molecule binding domain Pkinase PF00069.25 EAX97357.1 - 1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97357.1 - 5.8e-38 130.6 0.0 1.2e-37 129.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX97357.1 - 0.00012 21.1 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX97357.1 - 0.0016 17.8 0.0 0.0076 15.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EAX97357.1 - 0.018 15.0 0.0 0.064 13.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX97357.1 - 0.03 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX97357.1 - 0.16 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LMBR1 PF04791.16 EAX97358.1 - 5.6 5.7 7.7 6.6 5.5 7.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein EF-hand_1 PF00036.32 EAX97359.1 - 0.027 14.0 2.3 0.033 13.7 0.8 2.0 2 0 0 2 2 2 0 EF hand RNaseH_C PF09293.10 EAX97359.1 - 0.072 13.4 0.4 0.072 13.4 0.4 2.0 2 1 0 2 2 2 0 T4 RNase H, C terminal EF-hand_5 PF13202.6 EAX97359.1 - 0.34 10.5 2.8 0.38 10.3 1.3 1.9 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EAX97359.1 - 0.36 10.9 1.4 1.1 9.4 0.7 2.1 2 0 0 2 2 2 0 EF-hand domain Ribosomal_S2 PF00318.20 EAX97360.1 - 5.1e-32 110.8 0.6 2.8e-15 56.1 0.3 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 Pkinase PF00069.25 EAX97361.1 - 2.9e-67 226.8 0.1 4e-67 226.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97361.1 - 1.5e-40 139.2 0.0 2.1e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97361.1 - 2.7e-08 33.5 0.0 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX97361.1 - 2.6e-07 29.9 2.7 3.8e-07 29.4 0.5 2.1 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EAX97361.1 - 3e-05 23.7 1.1 0.00014 21.6 0.1 2.3 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.14 EAX97361.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX97361.1 - 0.00041 19.2 0.1 0.00068 18.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX97361.1 - 0.0018 18.2 0.3 0.0075 16.2 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-PolyVal PF18762.1 EAX97361.1 - 0.0088 16.0 1.9 0.038 13.9 0.6 2.3 2 0 0 2 2 2 1 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Choline_kinase PF01633.20 EAX97361.1 - 0.056 13.0 1.1 0.12 12.0 0.8 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EAX97361.1 - 0.16 11.5 1.5 1.5 8.4 0.2 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-binding PF00249.31 EAX97362.1 - 1.9e-23 82.4 2.8 1.5e-12 47.5 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97362.1 - 8.6e-19 67.5 1.2 3e-11 43.4 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EAX97362.1 - 0.074 13.4 1.5 0.66 10.4 0.2 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EAX97362.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WD40 PF00400.32 EAX97364.1 - 5.6e-19 68.1 0.2 1e-05 26.1 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX97364.1 - 9.2e-10 38.7 0.1 0.00073 19.8 0.1 3.7 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX97364.1 - 9.6e-06 25.1 0.3 0.0012 18.3 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 EAX97364.1 - 0.0019 16.8 0.0 0.0038 15.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain AAA_9 PF12781.7 EAX97364.1 - 0.069 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 ATP-binding dynein motor region IMUP PF15761.5 EAX97364.1 - 1.1 10.0 4.1 2.1 9.1 4.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein CENP-T_C PF15511.6 EAX97365.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX97365.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX97365.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX97365.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX97365.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX97365.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX97365.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX97365.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EAX97366.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX97366.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX97366.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX97366.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Pkinase PF00069.25 EAX97369.1 - 2.1e-54 184.7 0.4 2.3e-54 184.5 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97369.1 - 3.9e-27 95.2 0.1 5.1e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX97369.1 - 1e-09 37.7 0.0 1.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX97369.1 - 7.4e-06 25.5 0.2 3.6e-05 23.2 0.2 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX97369.1 - 0.00071 19.0 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX97369.1 - 0.0039 17.1 0.2 0.012 15.5 0.2 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX97369.1 - 0.04 13.6 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAX97369.1 - 0.11 12.1 0.5 0.36 10.4 0.1 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF3839 PF12943.7 EAX97371.1 - 3.8e-156 517.7 14.2 4.9e-156 517.3 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX97371.1 - 0.042 14.3 1.5 0.18 12.2 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX97371.1 - 1 9.9 8.2 2.1 8.8 1.0 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RLL PF10036.9 EAX97372.1 - 0.051 13.4 2.8 0.058 13.2 2.8 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Ly49 PF08391.10 EAX97372.1 - 0.35 11.3 3.0 0.41 11.0 3.0 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2897 PF11446.8 EAX97372.1 - 0.58 10.1 3.0 0.87 9.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) CHASE3 PF05227.13 EAX97374.1 - 0.0075 16.2 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 CHASE3 domain DUF3685 PF12452.8 EAX97374.1 - 0.056 13.1 0.2 0.078 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) DUF4108 PF13390.6 EAX97377.1 - 7.7e-63 210.7 7.8 8.6e-63 210.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX97378.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ResIII PF04851.15 EAX97379.1 - 4.9e-05 23.4 1.5 8.6e-05 22.6 1.5 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97379.1 - 0.00047 20.0 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAX97379.1 - 0.00069 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAX97379.1 - 0.0012 18.7 0.5 0.0026 17.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX97379.1 - 0.0094 16.3 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX97379.1 - 0.057 12.9 0.0 0.076 12.5 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX97379.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX97379.1 - 0.79 10.0 4.0 5.7 7.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) APG12 PF04110.13 EAX97379.1 - 1.1 9.7 4.2 0.42 11.1 1.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 KilA-N PF04383.13 EAX97380.1 - 5.4e-35 119.6 0.7 1.1e-34 118.6 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain T5orf172 PF10544.9 EAX97381.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX97381.1 - 0.0049 16.7 0.9 0.028 14.2 0.4 2.4 2 1 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX97382.1 - 5.4e-157 520.4 13.5 6.7e-157 520.1 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX97382.1 - 2.5 8.6 7.9 1.5 9.3 0.5 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAX97383.1 - 0.093 13.2 0.9 0.19 12.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Trypan_PARP PF05887.11 EAX97384.1 - 0.02 14.9 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX97384.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97385.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Peripla_BP_2 PF01497.18 EAX97387.1 - 0.0052 16.4 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein OST3_OST6 PF04756.13 EAX97388.1 - 9.7e-11 41.6 5.0 1.1e-10 41.4 5.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family RecG_N PF17190.4 EAX97389.1 - 0.032 14.9 2.7 0.032 14.9 2.7 4.0 3 1 1 5 5 5 0 RecG N-terminal helical domain NLRC4_HD2 PF17776.1 EAX97389.1 - 0.065 13.8 0.2 0.6 10.7 0.1 2.5 2 0 0 2 2 2 0 NLRC4 helical domain HD2 Atg14 PF10186.9 EAX97389.1 - 0.24 10.5 7.6 0.4 9.7 7.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EAX97389.1 - 1.7 8.7 17.5 0.62 10.1 0.8 3.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.6 EAX97389.1 - 2 9.1 8.1 0.44 11.2 1.4 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) YqzH PF14164.6 EAX97394.1 - 0.17 11.9 2.7 1 9.5 1.6 2.6 2 0 0 2 2 2 0 YqzH-like protein BBS2_Mid PF14783.6 EAX97395.1 - 0.00045 20.2 0.0 0.31 11.1 0.0 2.9 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 EAX97395.1 - 0.015 15.2 0.1 1.2 9.1 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat PSP PF04046.16 EAX97396.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97397.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX97398.1 - 0.042 14.3 0.5 0.09 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX97399.1 - 1.2e-50 169.4 33.0 6.8e-34 115.7 14.5 5.3 3 2 2 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX97399.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX97400.1 - 8.4e-12 45.1 0.2 1e-11 44.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAX97401.1 - 2e-79 266.5 10.7 2.5e-79 266.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX97401.1 - 0.054 13.9 0.3 0.06 13.8 0.3 1.2 1 0 0 1 1 1 0 Fez1 T5orf172 PF10544.9 EAX97402.1 - 1.4e-06 28.8 0.3 2.7e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain PHP_C PF13263.6 EAX97403.1 - 0.17 11.6 0.0 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX97403.1 - 0.51 10.3 8.3 0.17 11.8 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Peptidase_C1 PF00112.23 EAX97404.1 - 2.2e-71 240.4 7.6 3e-71 240.0 7.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAX97404.1 - 1.3e-12 47.9 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAX97404.1 - 4.8e-06 25.6 2.7 0.0019 17.1 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family FeoC PF09012.10 EAX97404.1 - 0.32 11.1 3.3 30 4.8 0.0 3.4 2 1 1 3 3 3 0 FeoC like transcriptional regulator Rer1 PF03248.13 EAX97405.1 - 7e-51 172.4 12.7 8.2e-51 172.1 12.7 1.1 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 EAX97405.1 - 6.3 6.4 6.6 2.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3839 PF12943.7 EAX97409.1 - 4.2e-156 517.5 12.4 5.3e-156 517.2 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX97409.1 - 0.12 12.8 5.2 2.1 8.8 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX97410.1 - 1.6e-06 27.8 5.4 3.1e-06 26.9 5.0 1.9 1 1 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX97410.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX97410.1 - 4.8e-05 23.2 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX97410.1 - 0.00021 21.3 4.0 0.00054 20.0 4.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97410.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97410.1 - 0.0014 18.4 0.8 0.0029 17.4 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX97410.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97410.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX97410.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX97410.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX97410.1 - 0.088 13.2 0.1 0.75 10.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX97410.1 - 0.29 11.4 4.8 4.7 7.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) LRR_5 PF13306.6 EAX97413.1 - 5.5e-15 55.5 1.9 5.5e-15 55.5 1.9 1.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97413.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_5 PF13306.6 EAX97414.1 - 1e-140 461.9 122.2 7.6e-31 106.7 1.6 8.3 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97414.1 - 3e-24 84.6 31.8 0.0002 21.1 0.1 13.2 7 3 9 16 16 16 8 Leucine rich repeat TMEM154 PF15102.6 EAX97414.1 - 0.0014 18.6 0.3 0.003 17.5 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAX97414.1 - 0.044 13.8 0.1 0.089 12.9 0.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4522 PF15022.6 EAX97414.1 - 0.085 13.1 0.5 0.78 10.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4522) Peptidase_M24 PF00557.24 EAX97415.1 - 1.3e-53 181.8 0.2 1.9e-53 181.3 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAX97415.1 - 9.2e-23 80.3 0.0 1.4e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Papo_T_antigen PF02380.15 EAX97415.1 - 0.72 10.0 4.8 2.1 8.5 4.8 1.7 1 0 0 1 1 1 0 T-antigen specific domain Myb_DNA-binding PF00249.31 EAX97416.1 - 2.2e-21 75.8 0.7 6.8e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97416.1 - 2.7e-18 65.9 4.4 1.7e-12 47.4 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97416.1 - 0.011 15.6 1.0 0.47 10.4 0.1 2.3 2 1 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX97416.1 - 0.013 15.7 0.7 0.046 13.9 0.2 1.9 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 WIYLD PF10440.9 EAX97416.1 - 0.019 14.8 0.2 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_4 PF13837.6 EAX97416.1 - 0.052 13.9 3.9 4.2 7.8 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NMT_C PF02799.15 EAX97416.1 - 0.11 12.0 0.2 0.17 11.4 0.2 1.3 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain RGS_DHEX PF18148.1 EAX97416.1 - 0.17 12.0 2.8 6.5 6.9 0.2 2.3 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain STIL_N PF15253.6 EAX97417.1 - 0.033 13.2 0.2 0.052 12.5 0.2 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus DUF1199 PF06712.11 EAX97417.1 - 0.068 13.2 0.1 0.56 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1199) Beta-Casp PF10996.8 EAX97418.1 - 3.9e-22 78.6 0.0 1.2e-21 77.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EAX97418.1 - 3.7e-21 75.4 0.0 1.2e-20 73.7 0.0 1.8 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EAX97418.1 - 1.3e-16 60.3 0.0 2.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF73-100_C PF11718.8 EAX97418.1 - 3.3e-16 59.5 0.6 5.5e-16 58.8 0.6 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 EAX97418.1 - 3.3e-14 53.4 0.8 6.6e-13 49.1 0.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAX97418.1 - 4.6e-10 39.3 0.0 2.5e-07 30.4 0.1 2.5 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EAX97418.1 - 4.3e-06 26.1 0.0 1.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 EAX97418.1 - 8.9e-05 22.4 0.3 0.001 19.0 0.2 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_helix PF13229.6 EAX97419.1 - 0.013 15.4 2.4 0.017 15.0 2.4 1.2 1 0 0 1 1 1 0 Right handed beta helix region Chlam_PMP PF02415.17 EAX97419.1 - 0.27 11.8 2.6 4.3 8.0 0.5 2.5 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 EAX97419.1 - 0.47 11.5 3.9 1.1 10.3 4.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Ank_2 PF12796.7 EAX97420.1 - 7.7e-06 26.4 0.3 6.2e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97420.1 - 0.00018 22.0 0.5 0.024 15.2 0.7 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97420.1 - 0.0046 17.4 0.1 2.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat DUF1955 PF09205.10 EAX97420.1 - 0.011 15.5 2.6 0.02 14.6 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1955) Fib_alpha PF08702.10 EAX97420.1 - 0.11 12.7 1.1 0.22 11.7 1.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BTB PF00651.31 EAX97421.1 - 6.4e-06 26.4 0.0 6.4e-06 26.4 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain PDEase_I PF00233.19 EAX97422.1 - 5.3e-26 91.8 2.2 3.3e-25 89.2 0.1 2.5 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX97422.1 - 5.6e-11 43.2 0.0 9.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EAX97422.1 - 4.3e-06 27.1 0.0 1.3e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 EAX97422.1 - 0.0003 21.1 0.0 0.00074 19.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EAX97423.1 - 1e-27 97.4 0.0 1.9e-17 64.1 0.0 3.3 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 EAX97423.1 - 7.3e-14 52.2 0.0 3.9e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 EAX97423.1 - 8.8e-10 39.0 0.0 8.1e-06 26.2 0.0 3.0 3 0 0 3 3 3 2 GAF domain PCI PF01399.27 EAX97424.1 - 6.3e-17 62.0 0.1 1.6e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 PCI domain PTR PF12789.7 EAX97425.1 - 1.6e-16 60.1 1.9 1.6e-16 60.1 1.9 6.1 5 2 1 6 6 6 1 Phage tail repeat like DUF3391 PF11871.8 EAX97425.1 - 0.0056 17.2 3.5 0.44 11.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAX97425.1 - 0.056 13.2 0.9 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX97426.1 - 0.03 14.8 0.8 0.059 13.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX97427.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX97428.1 - 4.7e-28 97.0 23.9 3.5e-23 81.4 7.8 4.4 3 1 1 4 4 3 2 Phage tail repeat like DUF4116 PF13475.6 EAX97428.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAX97428.1 - 0.55 10.7 0.0 0.55 10.7 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAX97428.1 - 2 8.0 28.8 5 6.7 9.0 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF445 PF04286.12 EAX97428.1 - 2.8 7.7 12.8 0.064 13.1 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) LRR_5 PF13306.6 EAX97429.1 - 4.2e-138 453.5 73.6 6e-30 103.8 6.4 6.2 2 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97429.1 - 3.2e-27 94.1 2.3 0.00013 21.7 0.0 13.2 7 5 9 16 16 16 8 Leucine rich repeat LRR_4 PF12799.7 EAX97429.1 - 3.6e-09 36.7 22.8 6.7 7.3 0.2 12.0 10 2 3 14 14 14 3 Leucine Rich repeats (2 copies) PRIMA1 PF16101.5 EAX97429.1 - 0.0045 17.0 0.2 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Reo_sigmaC_M PF17750.1 EAX97429.1 - 0.03 14.2 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein triple beta spiral TMEM190 PF15431.6 EAX97429.1 - 0.1 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 Transmembrane protein 190 DUF1963 PF09234.10 EAX97430.1 - 3.5e-10 40.7 0.1 4.8e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Sigma54_activ_2 PF14532.6 EAX97430.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_4 PF13637.6 EAX97431.1 - 6e-61 202.1 7.0 3.2e-09 37.1 0.0 8.4 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97431.1 - 3.7e-59 197.3 24.6 3.6e-19 69.1 1.4 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97431.1 - 1.6e-57 190.8 13.7 3.7e-10 39.9 0.0 6.3 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX97431.1 - 2.7e-55 182.5 14.2 1.3e-07 31.8 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EAX97431.1 - 2.2e-50 162.7 11.8 1.1e-06 28.5 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Shigella_OspC PF06128.11 EAX97431.1 - 2e-05 24.5 3.7 0.017 14.9 0.1 3.7 2 2 1 4 4 4 2 Shigella flexneri OspC protein Ish1 PF10281.9 EAX97431.1 - 0.0033 17.7 1.1 7.7 6.9 0.0 4.2 5 1 0 5 5 5 1 Putative stress-responsive nuclear envelope protein Ribosomal_S6 PF01250.17 EAX97431.1 - 0.017 15.4 0.6 21 5.5 0.0 3.7 1 1 2 4 4 4 0 Ribosomal protein S6 DUF3447 PF11929.8 EAX97431.1 - 0.022 14.7 7.5 2.4 8.2 0.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) FmdA_AmdA PF03069.15 EAX97431.1 - 0.024 13.5 0.1 4.6 6.0 0.0 2.7 1 1 2 3 3 3 0 Acetamidase/Formamidase family RRM_2 PF04059.12 EAX97431.1 - 0.048 13.9 0.9 0.25 11.6 0.2 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 SCVP PF17619.2 EAX97431.1 - 0.11 13.4 5.2 20 6.1 0.0 4.4 3 2 2 5 5 5 0 Secreted clade V proteins DUF4957 PF16318.5 EAX97431.1 - 0.33 10.9 4.3 2.9 7.8 0.4 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4957) Ank_4 PF13637.6 EAX97432.1 - 1.5e-43 146.6 1.9 7.1e-14 52.0 0.1 6.2 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97432.1 - 2.4e-39 133.8 4.8 9.4e-16 58.2 0.1 4.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97432.1 - 1.5e-37 126.4 0.0 4.9e-06 26.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX97432.1 - 1.2e-34 114.4 5.8 7.7e-07 29.0 0.0 7.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAX97432.1 - 1.8e-27 95.0 0.0 1.9e-09 37.6 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97432.1 - 2.4e-19 69.1 22.1 6.8e-18 64.4 8.2 4.8 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) Histone PF00125.24 EAX97434.1 - 1.9e-17 63.8 0.3 2.3e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAX97434.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EAX97434.1 - 0.054 13.1 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain AD PF09793.9 EAX97434.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Histone PF00125.24 EAX97435.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAX97435.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAX97435.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Actin PF00022.19 EAX97436.1 - 0.0057 15.3 0.1 0.024 13.3 0.0 1.9 2 0 0 2 2 2 1 Actin Drf_FH3 PF06367.16 EAX97436.1 - 0.039 13.6 0.3 0.039 13.6 0.3 2.3 2 1 1 3 3 3 0 Diaphanous FH3 Domain Ank_2 PF12796.7 EAX97437.1 - 9.7e-10 38.9 0.4 2.2e-05 24.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX97437.1 - 6.4e-08 32.5 10.6 1.8e-07 31.0 1.9 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX97437.1 - 1.1e-07 31.5 0.0 0.035 14.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX97437.1 - 3.5e-05 24.0 0.0 0.084 13.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97437.1 - 4e-05 24.1 0.6 0.0011 19.5 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97437.1 - 0.002 18.5 0.1 1 9.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DENN PF02141.21 EAX97438.1 - 4.2e-17 62.7 0.9 5.6e-17 62.3 0.1 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EAX97438.1 - 0.00027 21.6 3.4 0.00043 21.0 1.0 2.5 2 0 0 2 2 2 1 uDENN domain DUF3970 PF13113.6 EAX97438.1 - 0.047 13.9 0.2 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) SPA PF08616.10 EAX97438.1 - 0.12 12.3 0.7 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 Stabilization of polarity axis dDENN PF03455.19 EAX97438.1 - 0.19 11.7 1.4 0.34 10.9 0.1 2.1 2 0 0 2 2 2 0 dDENN domain Ank_2 PF12796.7 EAX97439.1 - 1.4e-78 259.5 46.7 1.1e-15 57.9 1.4 6.2 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97439.1 - 1.6e-58 194.3 15.5 1.9e-10 41.0 0.0 8.3 3 1 7 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX97439.1 - 7.2e-56 184.3 5.9 9.1e-07 29.1 0.1 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX97439.1 - 4.7e-52 173.4 9.7 8.7e-10 38.7 0.0 7.6 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97439.1 - 4.9e-45 146.3 15.5 3.2e-05 24.0 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat DUF3447 PF11929.8 EAX97439.1 - 8.1e-38 128.2 29.9 6e-37 125.4 6.6 5.0 2 1 2 5 5 5 3 Domain of unknown function (DUF3447) BRCT PF00533.26 EAX97439.1 - 0.00081 19.7 1.2 2.3 8.6 0.1 4.4 2 1 2 4 4 4 1 BRCA1 C Terminus (BRCT) domain Mic1 PF07035.12 EAX97439.1 - 0.0026 17.5 1.4 6.2 6.5 0.0 4.1 1 1 4 5 5 5 2 Colon cancer-associated protein Mic1-like MTES_1575 PF18741.1 EAX97439.1 - 0.018 15.2 0.1 24 5.2 0.0 4.2 3 2 1 4 4 4 0 REase_MTES_1575 MetallophosN PF16371.5 EAX97439.1 - 0.023 14.9 0.1 26 5.1 0.0 4.7 3 2 4 7 7 7 0 N terminal of Calcineurin-like phosphoesterase ASF1_hist_chap PF04729.13 EAX97439.1 - 0.093 12.7 0.0 22 5.0 0.0 3.5 2 1 0 3 3 3 0 ASF1 like histone chaperone Arg_repressor PF01316.21 EAX97439.1 - 0.34 10.7 1.7 20 5.0 0.0 4.2 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain Dpy-30 PF05186.13 EAX97440.1 - 2.7e-08 33.4 0.9 0.0096 15.6 0.0 2.7 2 1 1 3 3 3 2 Dpy-30 motif DNA_pol_phi PF04931.13 EAX97441.1 - 3.9e-08 31.9 0.1 8.9e-08 30.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase phi MOR2-PAG1_C PF14225.6 EAX97441.1 - 0.0072 16.2 0.8 0.027 14.4 0.0 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal SHE3 PF17078.5 EAX97441.1 - 0.21 11.3 2.4 0.92 9.2 0.1 2.7 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Ank_2 PF12796.7 EAX97442.1 - 3.9e-112 367.0 83.9 1.1e-17 64.4 2.6 10.9 3 2 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97442.1 - 8.3e-102 332.4 57.4 7e-11 42.4 0.1 17.5 3 1 16 19 19 19 17 Ankyrin repeats (many copies) Ank PF00023.30 EAX97442.1 - 4.5e-101 327.3 45.7 1.1e-06 28.8 0.0 17.0 17 0 0 17 17 17 16 Ankyrin repeat Ank_5 PF13857.6 EAX97442.1 - 6.9e-83 271.6 55.5 4.1e-11 42.9 0.1 12.5 4 1 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97442.1 - 1e-80 256.0 37.6 5.5e-05 23.2 0.0 17.9 18 0 0 18 18 18 16 Ankyrin repeat DUF3447 PF11929.8 EAX97442.1 - 1.7e-33 114.4 3.5 1.7e-33 114.4 3.5 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Peptidase_M16 PF00675.20 EAX97442.1 - 0.003 17.6 10.4 12 5.8 0.2 6.2 5 1 0 6 6 6 2 Insulinase (Peptidase family M16) Glyco_hydro_77 PF02446.17 EAX97443.1 - 4e-148 494.2 3.8 5.2e-148 493.8 3.8 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAX97443.1 - 2.8e-48 161.8 0.0 1.1e-20 73.3 0.0 3.7 3 0 0 3 3 3 3 Starch binding domain Ank_4 PF13637.6 EAX97444.1 - 6.5e-35 119.1 4.8 8.8e-09 35.7 0.1 6.7 4 1 3 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97444.1 - 1.4e-33 114.7 8.8 1.4e-33 114.7 8.8 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX97444.1 - 3.1e-30 103.3 2.7 1.2e-06 28.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX97444.1 - 1.9e-29 102.1 11.6 8.8e-15 55.1 3.3 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97444.1 - 2.5e-27 94.6 0.5 5.7e-12 45.6 0.0 4.2 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97444.1 - 2.1e-25 86.0 7.3 7.1e-06 26.0 0.2 7.5 7 0 0 7 7 7 3 Ankyrin repeat Bromodomain PF00439.25 EAX97445.1 - 1.2e-21 76.6 0.2 3.6e-21 75.0 0.1 1.9 2 0 0 2 2 2 1 Bromodomain N6-adenineMlase PF10237.9 EAX97445.1 - 0.0088 15.9 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase V_ATPase_I PF01496.19 EAX97446.1 - 4.6e-199 663.2 19.3 2e-151 505.7 1.6 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Hist_deacetyl PF00850.19 EAX97447.1 - 7.3e-78 262.1 0.0 9.3e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain eIF-6 PF01912.18 EAX97448.1 - 6.4e-76 254.1 0.7 5.9e-75 251.0 0.1 1.9 1 1 1 2 2 2 1 eIF-6 family DAN PF03045.15 EAX97448.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 DAN domain DUF4358 PF14270.6 EAX97449.1 - 0.065 13.5 3.2 0.14 12.5 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) HLH PF00010.26 EAX97449.1 - 1.5 8.8 3.8 0.96 9.5 0.1 2.7 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain Phage_min_cap2 PF06152.11 EAX97449.1 - 4.4 6.1 6.6 0.38 9.6 1.2 1.9 2 0 0 2 2 2 0 Phage minor capsid protein 2 Gemini_AL1_M PF08283.11 EAX97450.1 - 4.7 7.3 5.8 25 5.0 0.2 4.2 3 2 1 4 4 4 0 Geminivirus rep protein central domain PSP PF04046.16 EAX97451.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97452.1 - 0.046 14.3 4.9 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat T5orf172 PF10544.9 EAX97454.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX97455.1 - 4.8e-41 139.1 0.1 4.8e-41 139.1 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX97455.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Acyl_transf_2 PF02273.15 EAX97455.1 - 0.03 13.6 0.1 0.1 11.8 0.1 1.7 1 1 1 2 2 2 0 Acyl transferase FPN1 PF06963.12 EAX97455.1 - 0.087 11.4 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4108 PF13390.6 EAX97456.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX97457.1 - 2.1e-268 890.3 42.0 1.5e-145 485.6 13.8 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF4106) Pkinase PF00069.25 EAX97458.1 - 8.2e-44 149.9 0.0 9.7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97458.1 - 4.4e-17 62.2 0.0 7.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ca_chan_IQ PF08763.11 EAX97459.1 - 0.0065 16.7 0.1 0.03 14.5 0.0 2.2 2 0 0 2 2 2 1 Voltage gated calcium channel IQ domain FixO PF02433.15 EAX97459.1 - 0.1 12.0 0.1 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF3447 PF11929.8 EAX97460.1 - 0.0019 18.1 1.6 0.034 14.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97460.1 - 0.01 16.4 0.2 0.14 12.8 0.1 2.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97460.1 - 0.054 14.1 1.4 4.8 7.9 0.7 3.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) JMY PF15871.5 EAX97461.1 - 0.0071 15.7 0.2 0.0096 15.3 0.2 1.1 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein DNA_pol_B_2 PF03175.13 EAX97462.1 - 1.5e-37 129.6 15.3 6e-37 127.6 15.1 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Collagen PF01391.18 EAX97462.1 - 8.3e-06 25.5 11.3 1.3e-05 24.8 11.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX97462.1 - 0.0098 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Lac_bphage_repr PF06543.12 EAX97462.1 - 0.12 12.3 0.0 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor IBD PF10416.9 EAX97463.1 - 1e-19 70.8 0.1 2.3e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Myb_DNA-binding PF00249.31 EAX97465.1 - 4.8e-33 113.1 2.3 2.6e-17 62.7 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97465.1 - 1.8e-26 92.1 0.4 1.7e-15 57.0 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97465.1 - 3.1e-08 33.4 1.5 0.00035 20.4 0.1 2.3 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX97465.1 - 0.00036 20.5 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAX97465.1 - 0.012 15.8 0.8 1.7 8.9 0.2 2.5 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 dCMP_cyt_deam_1 PF00383.23 EAX97466.1 - 4.3e-15 55.4 0.2 5.4e-15 55.1 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EAX97466.1 - 6.1e-09 36.2 0.3 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EAX97466.1 - 0.13 11.9 1.8 0.59 9.7 0.2 2.0 1 1 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DUF667 PF05018.13 EAX97467.1 - 7.3e-17 61.7 0.0 1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) TMEM107 PF14995.6 EAX97468.1 - 3.3e-35 121.2 4.8 4.1e-35 120.9 4.8 1.1 1 0 0 1 1 1 1 Transmembrane protein Collectrin PF16959.5 EAX97468.1 - 3.1 7.5 6.9 1.4 8.7 2.9 2.3 2 1 0 2 2 2 0 Renal amino acid transporter BACK PF07707.15 EAX97469.1 - 0.0021 18.1 0.8 0.0063 16.6 0.0 2.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch Herpes_U44 PF04533.13 EAX97469.1 - 0.0064 16.1 0.6 0.012 15.2 0.6 1.5 1 0 0 1 1 1 1 Herpes virus U44 protein 7TMR-HDED PF07697.11 EAX97469.1 - 0.04 14.0 2.3 2.7 8.1 4.0 2.1 1 1 1 2 2 2 0 7TM-HD extracellular Pkinase PF00069.25 EAX97470.1 - 8.2e-57 192.6 0.0 9.7e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97470.1 - 6.6e-20 71.5 0.0 1.7e-19 70.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97470.1 - 3.5e-05 23.3 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAX97470.1 - 5.6e-05 23.2 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX97470.1 - 0.032 13.8 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EAX97470.1 - 0.05 13.2 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EAX97470.1 - 0.05 13.0 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX97470.1 - 0.081 12.5 0.1 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FGGY_N PF00370.21 EAX97471.1 - 2.4e-71 240.2 0.0 4.2e-71 239.4 0.0 1.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EAX97471.1 - 9.4e-36 123.4 0.0 1.4e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EAX97471.1 - 4.1e-07 29.8 0.0 0.00011 21.8 0.0 2.5 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 EAX97471.1 - 0.087 12.5 0.0 0.41 10.3 0.0 2.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region UCH PF00443.29 EAX97472.1 - 1.7e-12 47.4 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX97472.1 - 4.9e-10 39.9 0.0 1.3e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EAX97472.1 - 5.2e-05 23.0 0.1 7.7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Auto_anti-p27 PF06677.12 EAX97472.1 - 0.16 12.2 2.2 4.1 7.6 0.4 2.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-MIZ PF02891.20 EAX97472.1 - 0.39 10.5 3.7 0.13 12.1 0.6 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-ribbon_3 PF13248.6 EAX97472.1 - 2.1 7.9 4.2 7.1 6.2 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain PSP PF04046.16 EAX97473.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97474.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX97476.1 - 5.4e-49 164.1 32.1 4.6e-33 113.1 15.7 4.3 2 2 2 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX97476.1 - 0.043 13.6 0.9 0.086 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4404 PF14357.6 EAX97476.1 - 8.2 7.1 7.6 18 6.0 0.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4404) Adaptin_N PF01602.20 EAX97477.1 - 2.8e-20 72.4 10.5 6.7e-20 71.1 10.5 1.6 1 1 0 1 1 1 1 Adaptin N terminal region DUF4558 PF15104.6 EAX97478.1 - 0.028 14.4 6.2 0.037 14.1 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) DUF349 PF03993.12 EAX97478.1 - 1.5 9.2 11.0 0.087 13.1 5.4 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) DUF4588 PF15251.6 EAX97479.1 - 0.077 12.7 0.1 0.078 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) RIH_assoc PF08454.11 EAX97480.1 - 0.1 12.5 9.0 1.1 9.1 0.0 4.3 2 1 0 3 3 3 0 RyR and IP3R Homology associated RICTOR_V PF14668.6 EAX97480.1 - 0.14 12.4 0.1 0.57 10.5 0.1 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Cyclin_N PF00134.23 EAX97481.1 - 1.2e-24 86.5 1.2 2.6e-24 85.4 1.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAX97481.1 - 2.5e-10 40.5 0.2 5.9e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RNase_H2-Ydr279 PF09468.10 EAX97482.1 - 0.038 14.2 4.1 0.052 13.7 4.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ALMT PF11744.8 EAX97482.1 - 0.077 11.8 9.0 0.087 11.6 9.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SKA1 PF07160.12 EAX97482.1 - 0.1 12.4 8.1 0.11 12.3 8.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 RP-C_C PF11800.8 EAX97482.1 - 0.3 11.2 7.7 0.49 10.5 7.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DltD PF04914.12 EAX97482.1 - 0.38 10.1 10.9 0.46 9.8 10.9 1.0 1 0 0 1 1 1 0 DltD protein Hid1 PF12722.7 EAX97482.1 - 4.2 5.4 8.8 4.8 5.2 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3987 PF13148.6 EAX97482.1 - 8.7 5.2 10.6 11 4.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CCDC53 PF10152.9 EAX97482.1 - 9.8 6.6 14.5 14 6.0 14.5 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex HSP70 PF00012.20 EAX97483.1 - 5.3e-06 24.9 1.1 7.2e-06 24.5 0.1 1.6 2 0 0 2 2 2 1 Hsp70 protein TrmO PF01980.16 EAX97484.1 - 4.7e-26 91.3 0.0 5.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O Pkinase_Tyr PF07714.17 EAX97485.1 - 1.3e-53 182.0 0.0 2.8e-53 180.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAX97485.1 - 1.6e-50 171.9 0.0 3.8e-50 170.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EAX97485.1 - 0.00016 21.1 0.1 0.00087 18.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX97485.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX97485.1 - 0.05 12.4 0.0 0.47 9.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EAX97485.1 - 0.26 11.2 0.0 0.47 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFIIA PF03153.13 EAX97485.1 - 1.9 8.4 9.2 2.7 7.9 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phage_TAC_1 PF06222.11 EAX97486.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone Ribosomal_S4e PF00900.20 EAX97488.1 - 3e-26 91.1 0.1 1e-25 89.4 0.1 2.0 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 EAX97488.1 - 5.4e-16 58.4 4.9 1.1e-15 57.5 4.9 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 EAX97488.1 - 3.1e-14 52.4 0.0 7.1e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 EAX97488.1 - 6.5e-08 32.2 0.0 1.9e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EAX97488.1 - 0.00011 22.0 0.8 0.00011 22.0 0.8 3.2 3 1 1 4 4 4 1 KOW motif HD-ZIP_N PF04618.12 EAX97489.1 - 1.2 9.7 4.9 0.57 10.7 0.8 2.6 2 0 0 2 2 2 0 HD-ZIP protein N terminus Hydrolase_4 PF12146.8 EAX97490.1 - 9.5e-05 21.8 0.1 0.018 14.3 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PPI_Ypi1 PF07491.11 EAX97490.1 - 0.15 11.9 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor MG2 PF01835.19 EAX97491.1 - 0.00065 20.1 0.1 1.3 9.6 0.0 2.8 2 0 0 2 2 2 2 MG2 domain Prenyltrans PF00432.21 EAX97491.1 - 0.07 12.9 0.0 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Pkinase PF00069.25 EAX97492.1 - 1.2e-53 182.2 0.0 1.7e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97492.1 - 4.1e-24 85.2 0.0 6.5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAX97492.1 - 1e-05 25.2 0.6 0.0004 20.0 0.1 2.3 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 EAX97492.1 - 0.0031 17.2 0.2 0.061 12.9 0.1 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EAX97492.1 - 0.015 14.7 0.0 0.087 12.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EAX97492.1 - 0.042 13.8 0.1 0.16 11.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX97492.1 - 0.045 13.1 0.1 0.088 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAX97492.1 - 0.062 12.9 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.7 EAX97493.1 - 1.1e-13 51.6 1.2 0.00033 21.2 0.0 4.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97493.1 - 2.4e-07 31.2 3.6 2.1 9.0 0.0 5.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97493.1 - 7.7e-06 26.1 0.4 1.7 9.1 0.2 5.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97493.1 - 0.00026 21.2 4.3 74 4.4 0.0 7.2 8 0 0 8 8 8 0 Ankyrin repeat Ank PF00023.30 EAX97493.1 - 1.2 9.7 5.2 79 4.0 0.2 4.6 5 1 0 5 5 5 0 Ankyrin repeat Calreticulin PF00262.18 EAX97494.1 - 0.0051 15.7 0.2 0.075 11.9 0.1 2.1 1 1 1 2 2 2 2 Calreticulin family Ank_2 PF12796.7 EAX97496.1 - 1.9e-17 63.6 1.1 2.2e-08 34.5 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97496.1 - 1.2e-09 37.5 6.7 0.14 12.8 0.0 7.1 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 EAX97496.1 - 2.7e-09 37.4 3.7 0.00013 22.4 0.1 5.3 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97496.1 - 2.7e-08 33.9 0.8 0.033 14.5 0.0 5.4 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97496.1 - 1.4e-05 25.3 5.0 0.21 12.1 0.0 6.4 8 0 0 8 8 8 1 Ankyrin repeat AMNp_N PF10423.9 EAX97496.1 - 0.00062 19.4 0.1 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial AMP nucleoside phosphorylase N-terminus Oxysterol_BP PF01237.18 EAX97498.1 - 2.9e-46 158.0 6.1 5.4e-45 153.8 6.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein CBM60 PF16841.5 EAX97498.1 - 0.099 13.1 0.5 0.28 11.6 0.2 1.9 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding DUF4107 PF13389.6 EAX97500.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX97502.1 - 0.0094 15.6 0.1 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX97504.1 - 8.5e-43 144.8 0.2 8.5e-43 144.8 0.2 1.9 2 1 1 3 3 3 1 KilA-N domain RRP36 PF06102.12 EAX97504.1 - 0.062 13.3 6.3 0.12 12.3 6.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Hormone_1 PF00103.20 EAX97504.1 - 1 9.0 7.7 4 7.1 2.2 2.2 1 1 0 2 2 2 0 Somatotropin hormone family M60-like_N PF17291.2 EAX97505.1 - 1.1e-11 44.6 0.0 3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases DUF2194 PF09960.9 EAX97505.1 - 4.7e-05 22.0 0.5 7e-05 21.4 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Peptidase_M60 PF13402.6 EAX97505.1 - 0.0017 17.9 0.0 0.0054 16.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like Glyco_hydro_42M PF08532.10 EAX97505.1 - 0.048 13.1 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Ank_2 PF12796.7 EAX97508.1 - 1.5e-05 25.5 0.3 0.0028 18.2 0.3 3.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX97508.1 - 0.00018 21.4 0.2 0.00018 21.4 0.2 4.2 4 2 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX97508.1 - 0.0028 18.2 0.1 1.1 9.9 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97508.1 - 0.016 15.7 0.1 1.8 9.4 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF745 PF05335.13 EAX97508.1 - 0.023 14.4 1.1 0.043 13.5 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Vps4_C PF09336.10 EAX97508.1 - 0.037 14.0 0.1 0.093 12.7 0.1 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain APG6_N PF17675.1 EAX97508.1 - 0.068 13.7 6.5 0.19 12.3 6.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DinB PF05163.12 EAX97508.1 - 0.082 12.8 0.3 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 DinB family CC2-LZ PF16516.5 EAX97508.1 - 0.23 11.8 5.1 0.73 10.2 5.1 1.8 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UPF0515 PF15135.6 EAX97508.1 - 4.4 6.6 6.1 1.2 8.4 2.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 FAM76 PF16046.5 EAX97508.1 - 9.8 5.4 9.4 15 4.8 9.4 1.3 1 0 0 1 1 1 0 FAM76 protein Hexapep PF00132.24 EAX97509.1 - 8.9e-05 22.1 4.4 0.0052 16.5 3.0 2.8 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EAX97509.1 - 0.019 13.1 0.8 0.021 13.0 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EAX97509.1 - 0.053 13.3 5.8 0.57 10.0 0.5 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase EcoEI_R_C PF08463.10 EAX97510.1 - 0.034 14.3 0.3 10 6.2 0.1 3.4 2 1 0 2 2 2 0 EcoEI R protein C-terminal Pkinase PF00069.25 EAX97511.1 - 2.6e-51 174.5 0.0 3.1e-50 171.0 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97511.1 - 8.2e-44 149.8 0.0 8e-43 146.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97511.1 - 0.001 18.4 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like KASH_CCD PF14662.6 EAX97512.1 - 0.012 15.5 22.2 0.062 13.1 1.6 2.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 EAX97512.1 - 0.013 15.2 6.0 0.013 15.2 6.0 3.1 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 EAX97512.1 - 0.49 10.9 26.0 0.64 10.5 0.7 4.4 3 1 0 3 3 3 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 EAX97512.1 - 2.2 8.5 29.2 0.044 14.0 11.2 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Myb_DNA-binding PF00249.31 EAX97515.1 - 2.1e-16 59.8 1.6 7.1e-09 35.7 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97515.1 - 2.3e-13 50.1 4.9 8.7e-10 38.7 1.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97515.1 - 1.3e-06 28.2 2.4 0.008 16.0 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX97515.1 - 0.23 11.8 3.5 0.23 11.9 1.7 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EAX97516.1 - 8.9e-18 64.2 0.2 1e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97516.1 - 1.4e-17 63.7 8.0 8.7e-14 51.5 0.9 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97516.1 - 0.0026 17.6 1.6 0.0026 17.6 1.6 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EAX97517.1 - 1.9e-13 50.4 0.1 2.2e-06 27.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97517.1 - 2.3e-12 46.9 5.9 8.1e-11 42.0 1.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97517.1 - 0.00034 20.4 0.4 0.00034 20.4 0.4 2.1 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX97517.1 - 0.02 14.9 2.4 0.036 14.1 1.8 1.8 1 1 1 2 2 2 0 SLIDE Poxvirus_B22R_N PF13169.6 EAX97517.1 - 0.031 14.8 1.2 0.031 14.8 1.2 1.9 2 1 1 3 3 3 0 Poxvirus B22R protein N-terminal Phage_Cox PF10743.9 EAX97517.1 - 0.091 12.9 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Regulatory phage protein cox DUF3669 PF12417.8 EAX97517.1 - 0.12 12.6 0.9 0.34 11.1 0.1 2.1 2 1 0 2 2 2 0 Zinc finger protein Myb_DNA-bind_4 PF13837.6 EAX97517.1 - 0.17 12.3 0.4 0.17 12.3 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PSP PF04046.16 EAX97518.1 - 0.069 13.0 0.9 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97519.1 - 0.0068 16.7 2.6 2.9 8.9 0.3 2.9 3 0 0 3 3 3 2 TMP repeat DNA_pol_B_2 PF03175.13 EAX97521.1 - 1e-39 136.7 19.9 1e-39 136.7 19.9 2.5 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral HTH_32 PF13565.6 EAX97522.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain KIAA1430 PF13879.6 EAX97523.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue Metallophos PF00149.28 EAX97524.1 - 1.4e-26 94.2 0.1 2.4e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 EAX97524.1 - 1.2e-07 31.3 6.4 0.0033 17.4 1.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAX97524.1 - 6.7e-06 25.7 8.0 0.028 14.1 0.1 3.4 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.28 EAX97524.1 - 2.1e-05 24.2 9.9 0.00099 18.8 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX97524.1 - 0.0001 22.5 1.7 0.00092 19.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAX97524.1 - 0.0051 17.1 0.6 0.041 14.3 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Acyl-CoA_dh_2 PF08028.11 EAX97524.1 - 0.071 13.4 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_8 PF13181.6 EAX97524.1 - 1.1 9.6 10.1 3 8.3 0.9 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EAX97524.1 - 3.5 7.8 8.1 1.7 8.7 0.3 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF563 PF04577.14 EAX97525.1 - 6e-28 98.4 1.1 1e-27 97.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Orf78 PF06024.12 EAX97527.1 - 0.0056 16.9 0.4 0.0068 16.7 0.4 1.1 1 0 0 1 1 1 1 Orf78 (ac78) Chordopox_A13L PF05961.11 EAX97527.1 - 0.037 14.3 0.5 0.066 13.5 0.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein AMA-1 PF02430.15 EAX97527.1 - 0.044 12.7 1.1 0.05 12.6 1.1 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF4448 PF14610.6 EAX97527.1 - 0.051 13.3 0.2 0.054 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5113 PF17140.4 EAX97527.1 - 0.12 12.2 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) DUF2207 PF09972.9 EAX97527.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PLDc_N PF13396.6 EAX97529.1 - 0.0062 16.4 0.1 0.0062 16.4 0.1 1.8 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Pox_A32 PF04665.12 EAX97531.1 - 6.6e-08 32.3 2.0 9.4e-08 31.8 2.0 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX97531.1 - 0.0056 16.3 0.1 0.0074 15.9 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX97531.1 - 0.03 14.1 0.2 0.49 10.1 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX97531.1 - 0.072 13.1 2.1 1.3 9.0 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) APG12 PF04110.13 EAX97531.1 - 0.46 10.9 2.5 0.61 10.5 1.2 1.9 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF4108 PF13390.6 EAX97532.1 - 3.8e-57 192.2 4.2 4.3e-57 192.1 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAX97534.1 - 3.6e-18 65.9 0.1 2.1e-11 44.3 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97534.1 - 3.5e-11 42.3 0.0 0.064 13.8 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX97534.1 - 5.5e-11 42.8 0.1 2.4e-06 27.9 0.0 3.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX97534.1 - 1.6e-10 41.0 0.0 0.046 14.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX97534.1 - 4.6e-09 36.4 0.0 0.025 14.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Podoplanin PF05808.11 EAX97537.1 - 0.028 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Insulin_TMD PF17870.1 EAX97537.1 - 0.076 13.1 1.3 0.25 11.5 1.3 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Sec-ASP3 PF15432.6 EAX97537.1 - 0.085 13.0 0.2 0.085 13.0 0.2 4.2 4 0 0 4 4 4 0 Accessory Sec secretory system ASP3 Syndecan PF01034.20 EAX97537.1 - 0.37 10.7 3.3 0.92 9.5 3.3 1.6 1 0 0 1 1 1 0 Syndecan domain RNA_pol_Rpc4 PF05132.14 EAX97537.1 - 2.6 8.4 5.2 5.6 7.4 5.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec-ASP3 PF15432.6 EAX97538.1 - 0.068 13.3 0.1 0.068 13.3 0.1 2.3 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 Syndecan PF01034.20 EAX97538.1 - 0.15 12.0 2.5 0.36 10.8 2.5 1.6 1 0 0 1 1 1 0 Syndecan domain Peptidase_M8 PF01457.16 EAX97541.1 - 0.027 13.2 0.1 0.047 12.4 0.0 1.3 2 0 0 2 2 2 0 Leishmanolysin VirK PF06903.12 EAX97542.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 VirK protein DUF641 PF04859.12 EAX97543.1 - 0.03 14.6 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAX97543.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor MULE PF10551.9 EAX97544.1 - 2.6e-10 40.6 3.2 5.3e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX97544.1 - 0.002 18.2 1.1 0.0067 16.5 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX97544.1 - 0.005 15.8 0.3 0.0085 15.0 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family IBD PF10416.9 EAX97545.1 - 2.3e-44 150.5 1.1 3.2e-44 150.0 1.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD SMN PF06003.12 EAX97545.1 - 0.55 9.4 4.1 0.76 9.0 4.1 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CAP_N PF01213.19 EAX97545.1 - 6.8 6.1 13.0 13 5.2 13.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 EAX97546.1 - 0.021 14.6 0.1 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DisA-linker PF10635.9 EAX97547.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Mating_N PF12731.7 EAX97548.1 - 0.079 13.1 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Mating-type protein beta 1 TPR_8 PF13181.6 EAX97548.1 - 2.2 8.7 5.5 7.7 7.0 2.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5407 PF17401.2 EAX97549.1 - 0.28 11.5 8.5 0.8 10.0 0.3 3.5 2 1 0 3 3 3 0 Family of unknown function (DUF5407) MAP7 PF05672.11 EAX97549.1 - 2.4 7.8 47.4 0.09 12.5 28.9 2.1 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Trns_repr_metal PF02583.17 EAX97550.1 - 0.013 15.9 5.5 0.54 10.7 0.1 2.8 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor CorA PF01544.18 EAX97550.1 - 0.013 14.8 14.0 0.18 11.1 2.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PspB PF06667.12 EAX97550.1 - 0.017 15.2 7.6 0.089 12.9 1.3 3.2 2 1 1 3 3 3 0 Phage shock protein B Baculo_PEP_C PF04513.12 EAX97550.1 - 0.059 13.4 15.6 0.12 12.5 3.4 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FANCI_HD1 PF14679.6 EAX97550.1 - 0.065 13.2 1.1 0.59 10.1 0.0 2.9 2 1 2 4 4 4 0 FANCI helical domain 1 DsrC PF04358.13 EAX97550.1 - 0.065 13.8 3.7 0.067 13.7 1.1 2.0 1 1 1 2 2 2 0 DsrC like protein DUF4407 PF14362.6 EAX97550.1 - 0.28 10.5 10.6 0.41 10.0 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EAX97550.1 - 0.31 11.6 11.6 5.4 7.6 8.7 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Muted PF14942.6 EAX97550.1 - 0.33 11.3 19.1 3.5 8.0 12.5 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3683 PF12447.8 EAX97550.1 - 0.55 10.4 7.3 1.2 9.3 0.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3683) LMBR1 PF04791.16 EAX97550.1 - 0.57 9.0 8.4 0.66 8.8 8.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSCB_C PF07743.13 EAX97550.1 - 0.67 10.5 14.6 1.3 9.6 3.2 3.3 1 1 3 4 4 4 0 HSCB C-terminal oligomerisation domain TMPIT PF07851.13 EAX97550.1 - 0.71 9.1 15.6 0.8 8.9 7.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 EAX97550.1 - 0.83 7.5 10.5 0.94 7.3 10.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 EAX97550.1 - 0.96 9.6 17.4 5.4 7.2 11.0 3.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mer2 PF09074.10 EAX97550.1 - 1 9.2 18.6 2 8.2 14.9 2.1 1 1 1 2 2 2 0 Mer2 Fmp27_WPPW PF10359.9 EAX97550.1 - 1.2 7.9 18.3 0.076 11.8 7.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.10 EAX97550.1 - 1.3 9.2 20.9 6.7 6.9 6.3 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family AvrM-A PF18241.1 EAX97550.1 - 1.4 9.3 13.2 2.1 8.8 11.6 2.0 1 1 1 2 2 2 0 Flax-rust effector AvrM-A DUF2203 PF09969.9 EAX97550.1 - 1.7 9.4 12.0 0.35 11.6 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 EAX97550.1 - 1.7 7.6 12.6 2.4 7.1 12.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 EAX97550.1 - 1.9 8.9 16.7 0.15 12.4 3.0 3.5 1 1 2 3 3 3 0 Csm1 N-terminal domain Med4 PF10018.9 EAX97550.1 - 2.9 7.5 16.3 0.64 9.7 3.5 2.7 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.12 EAX97550.1 - 3 7.9 13.7 2.8 8.0 5.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EAX97550.1 - 3.7 7.9 8.2 1.5 9.1 0.5 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 EAX97550.1 - 6.9 7.0 14.7 11 6.3 4.3 4.1 3 1 0 3 3 3 0 Haemolysin XhlA NPV_P10 PF05531.12 EAX97550.1 - 7.8 7.0 14.0 1.2e+04 -3.2 13.9 3.8 1 1 0 1 1 0 0 Nucleopolyhedrovirus P10 protein Tnp_22_trimer PF17489.2 EAX97550.1 - 9.6 6.3 12.3 1.7 8.7 1.6 3.4 3 1 0 3 3 3 0 L1 transposable element trimerization domain MSP1b PF03429.13 EAX97551.1 - 0.27 9.3 0.2 0.32 9.0 0.2 1.1 1 0 0 1 1 1 0 Major surface protein 1B Nipped-B_C PF12830.7 EAX97551.1 - 1.4 8.8 6.4 2.3 8.1 6.4 1.5 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus TPR_19 PF14559.6 EAX97552.1 - 1.6e-42 143.9 32.2 3.9e-06 27.3 2.3 15.0 11 4 6 17 17 16 10 Tetratricopeptide repeat TPR_2 PF07719.17 EAX97552.1 - 8.3e-31 103.6 31.3 0.00034 20.5 0.0 16.6 16 0 0 16 16 16 7 Tetratricopeptide repeat TPR_14 PF13428.6 EAX97552.1 - 6.2e-30 101.3 16.3 0.0032 18.2 0.1 15.0 12 3 3 15 15 14 7 Tetratricopeptide repeat TPR_8 PF13181.6 EAX97552.1 - 1.8e-21 74.5 25.5 0.012 15.8 0.0 13.5 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAX97552.1 - 4.5e-21 75.2 21.0 2.2e-05 25.0 0.2 10.3 10 2 1 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX97552.1 - 1.1e-19 70.4 29.3 0.0026 18.0 0.8 11.8 10 3 1 11 11 11 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EAX97552.1 - 2.3e-17 62.0 37.2 0.0038 17.0 0.0 13.5 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 EAX97552.1 - 1.1e-14 53.8 13.1 0.0013 18.4 0.0 8.0 8 1 0 8 8 7 3 TPR repeat TPR_12 PF13424.6 EAX97552.1 - 4e-12 46.2 35.7 0.024 14.9 0.3 12.7 10 4 5 15 15 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 EAX97552.1 - 9.9e-10 37.8 18.3 0.57 10.3 0.1 11.0 12 1 1 13 13 11 3 Tetratricopeptide repeat BTAD PF03704.17 EAX97552.1 - 4.3e-07 30.5 0.5 0.66 10.4 0.0 5.2 4 0 0 4 4 4 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EAX97552.1 - 2.5e-06 27.4 2.9 9.3 6.4 0.0 8.4 8 1 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EAX97552.1 - 4.4e-06 27.0 33.6 4.4 8.2 0.0 13.5 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAX97552.1 - 5.9e-06 25.9 16.2 0.2 11.0 0.3 7.0 6 3 2 8 8 8 4 MalT-like TPR region ChAPs PF09295.10 EAX97552.1 - 6.6e-06 25.4 13.0 0.00013 21.1 0.9 4.5 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 EAX97552.1 - 4e-05 23.9 16.3 0.2 12.0 0.2 7.1 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX97552.1 - 0.00017 21.7 10.0 3.3 8.3 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAX97552.1 - 0.00019 21.2 16.9 6.6 6.7 0.0 9.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAX97552.1 - 0.00046 20.3 7.4 17 5.6 0.0 7.9 10 1 1 11 11 7 0 Tetratricopeptide repeat SPO22 PF08631.10 EAX97552.1 - 0.00076 19.1 2.5 0.00076 19.1 2.5 4.4 5 0 0 5 5 5 1 Meiosis protein SPO22/ZIP4 like FAT PF02259.23 EAX97552.1 - 0.0091 15.2 18.2 0.13 11.4 0.5 5.9 5 2 1 6 6 6 1 FAT domain NRBF2_MIT PF17169.4 EAX97552.1 - 0.012 15.8 5.3 1.3 9.3 0.3 4.4 4 0 0 4 4 3 0 MIT domain of nuclear receptor-binding factor 2 SRP_TPR_like PF17004.5 EAX97552.1 - 0.031 14.3 21.5 0.069 13.2 0.3 7.8 7 3 1 8 8 7 0 Putative TPR-like repeat TPR_21 PF09976.9 EAX97552.1 - 0.05 13.3 23.0 0.25 11.0 2.2 6.1 4 2 3 7 7 7 0 Tetratricopeptide repeat-like domain Sel1 PF08238.12 EAX97552.1 - 0.052 14.2 2.0 1.4 9.7 0.2 3.8 3 0 0 3 3 3 0 Sel1 repeat Alkyl_sulf_dimr PF14863.6 EAX97552.1 - 0.2 12.1 13.7 0.55 10.7 0.6 5.4 5 1 0 5 5 4 0 Alkyl sulfatase dimerisation Ank_2 PF12796.7 EAX97554.1 - 2.2e-119 390.3 61.3 2e-17 63.5 2.8 9.8 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97554.1 - 1.2e-111 360.8 38.3 4.3e-08 33.2 0.3 17.2 17 0 0 17 17 17 17 Ankyrin repeat Ank_4 PF13637.6 EAX97554.1 - 1.5e-104 341.1 32.4 1.3e-10 41.6 0.1 16.8 2 1 15 17 17 17 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97554.1 - 6.6e-102 332.2 49.0 1.3e-11 44.5 0.0 12.6 3 3 12 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97554.1 - 1.5e-83 264.7 36.1 4.5e-05 23.5 0.2 17.2 17 0 0 17 17 17 17 Ankyrin repeat PAZ_siRNAbind PF12212.8 EAX97554.1 - 0.00014 21.7 2.4 4 7.3 0.0 5.3 4 1 0 5 5 5 2 PAZ domain MCC-bdg_PDZ PF10506.9 EAX97554.1 - 0.00029 20.8 1.4 9.1 6.4 0.0 6.0 7 0 0 7 7 7 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Peptidase_M16 PF00675.20 EAX97554.1 - 0.00098 19.1 0.5 13 5.7 0.0 5.4 6 0 0 6 6 6 1 Insulinase (Peptidase family M16) Orn_Arg_deC_N PF02784.16 EAX97554.1 - 0.026 13.9 0.0 0.55 9.6 0.0 2.7 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF3447 PF11929.8 EAX97555.1 - 6.5e-26 90.1 4.5 6.5e-26 90.1 4.5 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX97556.1 - 2.9e-17 62.5 2.3 1.4e-09 38.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97556.1 - 5.3e-15 55.1 1.6 6.5e-05 23.2 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX97556.1 - 8.7e-15 55.1 2.3 1.1e-11 45.2 1.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97556.1 - 4.1e-13 49.6 0.1 0.00038 21.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97556.1 - 1.9e-09 36.9 0.7 0.067 13.8 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat PE PF00934.20 EAX97556.1 - 0.069 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 PE family Ank_2 PF12796.7 EAX97557.1 - 1.6e-19 70.3 1.2 5.9e-07 30.0 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97557.1 - 3.6e-19 68.6 0.1 3.3e-06 27.3 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97557.1 - 8.3e-17 61.3 0.1 3.2e-08 33.9 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX97557.1 - 2.7e-10 40.2 0.0 0.013 16.0 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX97557.1 - 2.4e-08 33.6 0.0 0.054 14.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX97558.1 - 2.2e-24 85.5 2.6 4.7e-09 36.6 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97558.1 - 2.7e-24 84.9 6.5 1.3e-08 34.9 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97558.1 - 5.9e-23 81.3 0.3 9.8e-14 51.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97558.1 - 1.1e-22 77.6 0.7 8.4e-08 31.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX97558.1 - 1.4e-20 72.7 0.1 9e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat ubiquitin PF00240.23 EAX97559.1 - 1.4e-22 79.2 0.1 2.9e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX97559.1 - 5.3e-10 39.0 0.3 1.2e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX97559.1 - 0.00043 20.7 0.7 0.0017 18.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX97559.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 EAX97560.1 - 1.3e-14 53.7 0.1 1.4e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX97560.1 - 5.6e-06 26.1 0.1 6.4e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX97560.1 - 0.00067 20.0 0.0 0.00071 19.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX97560.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MOR2-PAG1_mid PF14228.6 EAX97561.1 - 0.011 13.4 0.0 0.022 12.4 0.0 1.4 1 0 0 1 1 1 0 Cell morphogenesis central region DUF1493 PF07377.12 EAX97562.1 - 0.034 14.6 0.6 0.076 13.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ank_4 PF13637.6 EAX97563.1 - 3e-45 152.0 10.6 5.9e-13 49.1 0.1 8.3 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97563.1 - 1.1e-43 147.6 20.2 1.8e-16 60.5 1.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97563.1 - 1.2e-41 139.3 10.1 4.7e-06 26.8 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX97563.1 - 1.5e-38 130.4 11.9 1.7e-10 40.9 0.3 5.7 3 1 3 6 6 6 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97563.1 - 1.7e-38 130.4 7.5 1.7e-38 130.4 7.5 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAX97563.1 - 2e-33 110.7 16.5 3.9e-05 23.7 0.2 9.3 9 0 0 9 9 9 6 Ankyrin repeat PH_8 PF15409.6 EAX97563.1 - 0.15 12.3 1.8 1.1e+02 3.2 0.0 4.7 3 1 3 7 7 7 0 Pleckstrin homology domain Rap_GAP PF02145.15 EAX97564.1 - 2.7e-44 151.0 0.0 7.7e-44 149.5 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Ykof PF07615.11 EAX97564.1 - 0.18 12.3 2.2 0.68 10.5 0.1 3.1 4 0 0 4 4 4 0 YKOF-related Family Baculo_LEF-11 PF06385.12 EAX97564.1 - 0.53 10.8 5.0 0.4 11.2 1.1 2.9 3 0 0 3 3 3 0 Baculovirus LEF-11 protein C2 PF00168.30 EAX97566.1 - 4.8e-11 42.9 0.0 8.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Sad1_UNC PF07738.13 EAX97567.1 - 0.00016 21.7 1.1 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EAX97567.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain CagE_TrbE_VirB PF03135.14 EAX97567.1 - 0.031 14.4 0.9 0.066 13.3 0.2 1.9 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system CARD PF00619.21 EAX97567.1 - 0.13 12.3 0.0 0.87 9.7 0.0 2.3 2 0 0 2 2 2 0 Caspase recruitment domain PSP PF04046.16 EAX97568.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX97569.1 - 0.15 12.7 8.0 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX97569.1 - 6 6.9 8.5 6.6 6.7 8.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR PF12789.7 EAX97571.1 - 1.5e-21 76.2 25.9 1.8e-11 43.9 5.6 4.8 5 0 0 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAX97571.1 - 0.031 14.0 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GST_C PF00043.25 EAX97571.1 - 2 8.7 3.9 4 7.7 0.5 2.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_MLP1_2 PF07926.12 EAX97572.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX97572.1 - 0.086 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX97572.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF2433 PF10360.9 EAX97573.1 - 0.065 13.3 3.3 2.4 8.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) GAGA_bind PF06217.12 EAX97573.1 - 0.094 13.0 1.5 0.16 12.3 1.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family K-box PF01486.17 EAX97573.1 - 4 7.7 8.6 5.1 7.3 3.1 2.6 2 0 0 2 2 2 0 K-box region Arf PF00025.21 EAX97574.1 - 1.2e-73 246.3 0.0 1.4e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAX97574.1 - 4.7e-13 49.4 0.0 6.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAX97574.1 - 1.8e-11 43.9 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EAX97574.1 - 1.9e-11 43.8 0.0 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX97574.1 - 7e-10 38.6 0.7 1.6e-06 27.5 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX97574.1 - 2.1e-08 33.8 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX97574.1 - 9.4e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAX97574.1 - 0.017 14.4 0.1 0.057 12.7 0.0 1.7 1 1 1 2 2 2 0 6-phosphofructo-2-kinase MeaB PF03308.16 EAX97574.1 - 0.13 11.2 0.0 0.5 9.3 0.0 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cnn_1N PF07989.11 EAX97575.1 - 2.2e-05 24.5 0.6 2.7e-05 24.2 0.6 1.4 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 HALZ PF02183.18 EAX97575.1 - 0.0047 17.1 0.5 0.01 16.0 0.5 1.7 1 1 0 1 1 1 1 Homeobox associated leucine zipper CENP-Q PF13094.6 EAX97575.1 - 0.005 17.1 0.1 0.0059 16.8 0.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MAD PF05557.13 EAX97575.1 - 0.014 13.8 0.1 0.014 13.8 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.11 EAX97575.1 - 0.02 15.3 0.4 0.082 13.3 0.1 2.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TRAF_BIRC3_bd PF16673.5 EAX97575.1 - 0.042 13.6 0.3 0.089 12.6 0.2 1.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain TMF_DNA_bd PF12329.8 EAX97575.1 - 0.049 13.6 1.4 0.093 12.7 1.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 EAX97575.1 - 0.053 13.6 0.2 0.087 12.9 0.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor BLOC1_2 PF10046.9 EAX97575.1 - 0.058 13.7 1.0 0.36 11.1 0.7 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 EAX97575.1 - 0.067 13.0 1.5 0.12 12.2 1.3 1.5 2 0 0 2 2 2 0 Septum formation initiator DASH_Hsk3 PF08227.11 EAX97575.1 - 0.072 13.5 1.3 0.072 13.5 1.3 1.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like MerR-DNA-bind PF09278.11 EAX97575.1 - 0.083 13.4 0.5 1.6 9.3 0.7 2.1 1 1 1 2 2 2 0 MerR, DNA binding DUF4094 PF13334.6 EAX97575.1 - 0.13 12.7 0.2 2.2 8.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) NOT2_3_5 PF04153.18 EAX97576.1 - 1.2e-07 31.9 0.8 2.8e-07 30.7 0.8 1.9 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Acetyltransf_1 PF00583.25 EAX97577.1 - 3e-11 43.6 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAX97577.1 - 3.5e-09 37.0 0.1 5.8e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAX97577.1 - 3.5e-09 36.7 0.0 6.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAX97577.1 - 1.8e-05 24.6 0.0 4.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Pkinase PF00069.25 EAX97578.1 - 2.5e-60 204.1 0.0 3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97578.1 - 9.2e-21 74.3 0.0 2e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX97578.1 - 1.5e-05 25.1 0.0 0.0036 17.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX97578.1 - 0.00037 19.9 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX97578.1 - 0.0015 18.1 0.2 0.0053 16.4 0.0 1.8 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EAX97578.1 - 0.039 13.5 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAX97578.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX97578.1 - 0.13 11.9 0.0 0.64 9.6 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Spore_III_AF PF09581.10 EAX97581.1 - 0.034 14.2 0.7 0.048 13.7 0.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SUD-M PF11633.8 EAX97581.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain TMP PF05017.14 EAX97584.1 - 0.12 13.1 7.2 6.3 7.9 0.8 3.3 3 0 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX97584.1 - 5.2 7.0 8.2 5.5 7.0 8.2 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAX97585.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ATP_bind_3 PF01171.20 EAX97586.1 - 1.2e-19 70.7 0.1 2.2e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 PP-loop family DUF2373 PF10180.9 EAX97587.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Sel1 PF08238.12 EAX97588.1 - 5.6e-09 36.4 0.6 0.086 13.6 0.1 3.9 3 0 0 3 3 3 3 Sel1 repeat FAT PF02259.23 EAX97588.1 - 0.072 12.3 1.4 0.1 11.8 1.4 1.2 1 0 0 1 1 1 0 FAT domain HEPN_AbiA_CTD PF18732.1 EAX97589.1 - 0.007 16.3 0.6 0.007 16.3 0.6 1.7 2 0 0 2 2 2 1 HEPN like, Abia C-terminal domain HSCB_C PF07743.13 EAX97589.1 - 0.023 15.2 3.3 0.097 13.2 0.8 2.4 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Pannexin_like PF12534.8 EAX97589.1 - 0.025 13.7 2.4 0.029 13.5 2.4 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 ArsA_ATPase PF02374.15 EAX97589.1 - 0.029 13.6 1.4 0.034 13.3 1.4 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase GIT_CC PF16559.5 EAX97589.1 - 0.03 14.2 3.5 2.3 8.1 0.9 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF349 PF03993.12 EAX97589.1 - 0.034 14.4 2.1 0.9 9.9 0.2 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Com_YlbF PF06133.11 EAX97589.1 - 0.043 14.4 3.4 0.043 14.4 3.4 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA ATG16 PF08614.11 EAX97589.1 - 0.072 13.3 5.3 0.1 12.8 5.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2031 PF09592.10 EAX97589.1 - 0.13 11.8 13.1 0.09 12.3 11.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) Prp18 PF02840.15 EAX97589.1 - 0.19 11.8 3.2 0.35 10.9 3.2 1.4 1 0 0 1 1 1 0 Prp18 domain DUF2203 PF09969.9 EAX97589.1 - 0.2 12.4 3.6 0.15 12.7 1.6 1.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CdiI_2 PF18593.1 EAX97589.1 - 0.25 12.0 3.0 2.1 9.1 0.1 2.6 2 1 1 3 3 3 0 CdiI immunity protein GAT PF03127.14 EAX97589.1 - 0.33 11.3 3.7 3.4 8.0 0.1 3.0 1 1 2 3 3 3 0 GAT domain DUF3987 PF13148.6 EAX97589.1 - 0.54 9.2 3.8 0.77 8.7 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) CpxA_peri PF16527.5 EAX97589.1 - 5 7.5 7.6 1.2 9.5 2.7 2.2 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain TFIIA PF03153.13 EAX97590.1 - 9.2 6.1 33.5 11 5.9 33.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S27e PF01667.17 EAX97591.1 - 2.8e-15 55.8 0.3 3.6e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DZR PF12773.7 EAX97591.1 - 0.045 13.8 1.8 0.32 11.0 1.9 2.0 1 1 1 2 2 1 0 Double zinc ribbon Yippee-Mis18 PF03226.14 EAX97591.1 - 0.083 13.1 0.1 8.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_7 PF02591.15 EAX97591.1 - 7.1 6.9 7.2 7.1 6.9 0.4 2.7 3 1 0 3 3 3 0 C4-type zinc ribbon domain Peptidase_M8 PF01457.16 EAX97592.1 - 2.5e-29 102.3 0.1 2.7e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Leishmanolysin Orthoreo_P10 PF07204.11 EAX97592.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM154 PF15102.6 EAX97592.1 - 0.012 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Synaptobrevin PF00957.21 EAX97592.1 - 0.25 11.1 1.7 0.3 10.9 0.4 1.8 2 0 0 2 2 2 0 Synaptobrevin Peptidase_M8 PF01457.16 EAX97593.1 - 2.1e-31 109.2 0.0 5.1e-31 108.0 0.0 1.5 2 0 0 2 2 2 1 Leishmanolysin Peptidase_M8 PF01457.16 EAX97594.1 - 5.3e-31 107.9 0.0 3.1e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Leishmanolysin Mid2 PF04478.12 EAX97594.1 - 0.0039 17.0 0.1 0.0082 16.0 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAX97594.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family LRR_5 PF13306.6 EAX97595.1 - 5.5e-144 472.5 153.1 2.3e-25 89.0 15.4 7.2 1 1 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97595.1 - 2.5e-24 84.8 34.1 0.038 13.8 0.8 16.2 7 5 13 20 20 20 16 Leucine rich repeat Herpes_gI PF01688.17 EAX97595.1 - 0.076 12.9 3.9 3.2 7.7 0.1 4.5 3 2 1 4 4 4 0 Alphaherpesvirus glycoprotein I Gly-zipper_Omp PF13488.6 EAX97599.1 - 0.0045 17.0 9.1 0.008 16.2 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX97599.1 - 0.26 11.6 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX97599.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif ABC_tran PF00005.27 EAX97600.1 - 1.1e-35 123.1 0.0 2.1e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAX97600.1 - 3.8e-32 112.0 15.6 5e-32 111.6 15.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EAX97600.1 - 1.7e-05 24.4 0.2 8.7e-05 22.0 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAX97600.1 - 6e-05 23.5 0.1 0.00031 21.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX97600.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EAX97600.1 - 0.00077 19.3 0.3 0.00077 19.3 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAX97600.1 - 0.0028 17.9 0.0 0.028 14.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAX97600.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EAX97600.1 - 0.0092 16.4 0.3 0.16 12.4 0.3 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAX97600.1 - 0.044 13.7 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 EAX97600.1 - 0.046 13.7 0.1 0.77 9.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EAX97600.1 - 0.052 14.0 2.3 0.24 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAX97600.1 - 0.06 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX97600.1 - 0.078 12.5 3.5 0.2 11.2 0.3 3.0 3 1 0 3 3 3 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EAX97600.1 - 0.099 13.0 0.1 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 EAX97600.1 - 0.11 12.0 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAX97600.1 - 0.15 12.2 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 1 0 50S ribosome-binding GTPase Myb_DNA-binding PF00249.31 EAX97601.1 - 1e-28 99.3 1.6 2.4e-13 50.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97601.1 - 3.2e-27 94.6 1.1 6.5e-16 58.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97601.1 - 0.0014 18.5 0.1 0.037 13.9 0.0 2.9 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX97601.1 - 0.0051 16.8 0.1 0.63 10.1 0.0 2.4 1 1 1 2 2 2 1 SLIDE DUF4167 PF13763.6 EAX97601.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) Myb_DNA-bind_4 PF13837.6 EAX97601.1 - 0.014 15.7 1.0 0.69 10.3 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX97601.1 - 0.03 14.5 0.3 0.64 10.2 0.2 2.6 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-binding PF00249.31 EAX97602.1 - 1e-28 99.3 1.6 2.4e-13 50.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97602.1 - 3.2e-27 94.6 1.1 6.5e-16 58.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97602.1 - 0.0014 18.5 0.1 0.037 13.9 0.0 2.9 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAX97602.1 - 0.0051 16.8 0.1 0.63 10.1 0.0 2.4 1 1 1 2 2 2 1 SLIDE DUF4167 PF13763.6 EAX97602.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) Myb_DNA-bind_4 PF13837.6 EAX97602.1 - 0.014 15.7 1.0 0.69 10.3 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX97602.1 - 0.03 14.5 0.3 0.64 10.2 0.2 2.6 2 1 0 2 2 2 0 Rap1 Myb domain Guanylate_cyc PF00211.20 EAX97604.1 - 1.8e-43 148.3 0.0 3.7e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX97604.1 - 9.3e-14 51.6 1.2 3.3e-13 49.8 1.2 2.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EAX97604.1 - 7.6e-06 26.1 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAX97604.1 - 0.00021 21.3 0.2 0.00055 19.9 0.2 1.7 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAX97604.1 - 0.0078 15.7 0.1 0.017 14.5 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated DUF1129 PF06570.11 EAX97605.1 - 0.07 12.6 4.6 0.089 12.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DPM2 PF07297.12 EAX97605.1 - 0.56 10.6 9.0 0.77 10.1 9.0 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pkinase PF00069.25 EAX97607.1 - 2.6e-33 115.5 0.0 3.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97607.1 - 3.5e-13 49.5 0.0 4.1e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97607.1 - 5.9e-06 25.8 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX97607.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EAX97607.1 - 0.092 12.3 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.31 EAX97608.1 - 6.7e-26 90.2 0.4 5.1e-12 45.8 0.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97608.1 - 5.6e-21 74.6 4.5 1.8e-13 50.5 0.8 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97608.1 - 2.4e-05 24.1 0.8 0.16 11.9 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX97608.1 - 4.6e-05 23.4 0.8 0.088 12.8 0.1 2.9 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EAX97608.1 - 0.0025 18.2 1.6 0.084 13.3 0.1 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX97608.1 - 0.0042 17.2 0.5 0.58 10.4 0.0 2.6 3 0 0 3 3 3 1 Rap1 Myb domain Myb_DNA-binding PF00249.31 EAX97609.1 - 4.6e-28 97.2 0.0 2.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97609.1 - 7.1e-24 83.8 3.1 4.6e-15 55.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97609.1 - 3.8e-06 26.7 3.2 5.8e-06 26.1 1.3 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX97609.1 - 0.00051 20.2 0.5 0.00092 19.4 0.5 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX97609.1 - 0.00096 19.2 0.1 1.5 8.9 0.1 3.0 1 1 1 3 3 3 2 SLIDE Myb_DNA-binding PF00249.31 EAX97610.1 - 6e-28 96.8 0.0 3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97610.1 - 1.3e-23 83.0 2.8 5.2e-15 55.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97610.1 - 5.6e-06 26.2 2.1 1.4e-05 24.9 1.1 1.9 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX97610.1 - 0.00058 20.0 0.5 0.001 19.2 0.5 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX97610.1 - 0.0017 18.3 0.1 1.7 8.7 0.1 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-binding PF00249.31 EAX97611.1 - 4.3e-28 97.3 0.0 2.5e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97611.1 - 7.6e-24 83.7 2.3 4.1e-15 55.8 0.1 2.5 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97611.1 - 1.1e-05 25.2 0.6 4.8e-05 23.2 0.1 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAX97611.1 - 0.00051 20.2 0.7 0.00092 19.4 0.7 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAX97611.1 - 0.0014 18.6 0.0 1.4 9.0 0.1 2.7 1 1 1 2 2 2 2 SLIDE SMC_N PF02463.19 EAX97612.1 - 1.5e-37 129.2 64.4 2.4e-18 66.4 30.2 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAX97612.1 - 2.3e-14 53.7 0.0 8.5e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 EAX97612.1 - 2e-09 37.6 31.3 2e-09 37.6 31.3 4.5 1 1 3 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 EAX97612.1 - 3.5e-07 30.3 39.3 4.3e-06 26.8 15.5 5.0 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX97612.1 - 4.6e-05 23.1 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EAX97612.1 - 0.00013 22.5 37.3 0.00013 22.5 37.3 7.4 1 1 3 4 4 1 1 AAA domain SbcCD_C PF13558.6 EAX97612.1 - 0.0045 17.2 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fez1 PF06818.15 EAX97612.1 - 0.032 14.7 109.7 0.041 14.3 11.7 6.4 2 2 3 5 5 5 0 Fez1 DASH_Hsk3 PF08227.11 EAX97612.1 - 1.4 9.3 4.2 42 4.6 0.1 4.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like FlgM PF04316.13 EAX97612.1 - 1.8 9.0 6.5 1.5 9.2 1.7 3.5 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Spc7 PF08317.11 EAX97612.1 - 6.4 5.6 122.1 0.0061 15.5 16.4 6.2 3 2 1 5 5 5 0 Spc7 kinetochore protein ILEI PF15711.5 EAX97613.1 - 0.09 13.3 0.1 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 Interleukin-like EMT inducer Pox_D5 PF03288.16 EAX97614.1 - 9.5e-06 26.0 3.0 6.8e-05 23.3 3.0 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX97614.1 - 0.052 14.2 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX97614.1 - 0.12 12.4 0.4 0.22 11.5 0.3 1.4 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4108 PF13390.6 EAX97615.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX97617.1 - 1e-06 28.4 2.2 1e-06 28.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX97617.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX97617.1 - 5.1e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX97617.1 - 0.00014 21.9 3.2 0.00034 20.7 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97617.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97617.1 - 0.0014 18.5 0.5 0.0039 17.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX97617.1 - 0.0019 17.9 0.4 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97617.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX97617.1 - 0.073 12.6 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX97617.1 - 0.09 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX97617.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF2805 PF10985.8 EAX97617.1 - 0.15 12.4 2.9 0.74 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX97617.1 - 0.4 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX97618.1 - 1.2e-19 70.2 0.1 1.2e-19 70.2 0.1 2.0 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX97618.1 - 0.027 14.6 0.0 0.066 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Gly_rich PF12810.7 EAX97619.1 - 1.3e-18 67.8 32.4 1.3e-18 67.8 32.4 1.4 2 0 0 2 2 2 1 Glycine rich protein DUF3839 PF12943.7 EAX97620.1 - 1e-27 97.2 0.3 1.2e-27 96.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2897 PF11446.8 EAX97621.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX97622.1 - 6e-63 211.0 5.9 6.6e-63 210.9 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX97623.1 - 2.1e-05 24.9 2.6 0.00011 22.7 2.6 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX97623.1 - 0.051 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Spectrin PF00435.21 EAX97624.1 - 0.0011 19.4 5.7 0.0011 19.4 5.7 3.6 2 1 1 3 3 3 1 Spectrin repeat GIT_CC PF16559.5 EAX97624.1 - 0.0016 18.2 0.4 0.0016 18.2 0.4 3.3 3 1 1 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor Mce4_CUP1 PF11887.8 EAX97624.1 - 0.023 14.1 0.5 0.035 13.6 0.5 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3287 PF11690.8 EAX97624.1 - 0.28 10.9 0.1 0.28 10.9 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3287) Pox_A_type_inc PF04508.12 EAX97624.1 - 0.44 10.5 6.7 0.33 10.9 1.7 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 EAX97624.1 - 0.86 8.6 25.5 0.032 13.3 16.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NEMO PF11577.8 EAX97624.1 - 0.99 9.5 16.7 0.037 14.0 4.1 3.4 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO WD40_alt PF14077.6 EAX97624.1 - 1.5 8.7 6.5 11 6.0 0.4 3.9 4 0 0 4 4 4 0 Alternative WD40 repeat motif OSR1_C PF12202.8 EAX97625.1 - 0.0021 18.2 0.1 0.0042 17.3 0.1 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain DUF1154 PF06631.11 EAX97625.1 - 0.024 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) ORF6C PF10552.9 EAX97625.1 - 0.031 14.4 0.3 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 ORF6C domain Myb_DNA-binding PF00249.31 EAX97626.1 - 2.2e-26 91.7 1.0 4.4e-14 52.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97626.1 - 5.4e-20 71.4 0.3 5.7e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAX97626.1 - 0.0044 17.2 0.2 0.0084 16.3 0.0 1.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EAX97626.1 - 0.0057 16.5 0.3 0.17 11.8 0.0 2.4 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAX97626.1 - 0.027 14.5 0.1 1.5 8.8 0.0 2.5 1 1 2 3 3 3 0 SLIDE Myb_DNA-binding PF00249.31 EAX97627.1 - 1e-27 96.0 1.2 9e-15 54.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97627.1 - 1.8e-24 85.8 4.2 1.7e-17 63.4 0.2 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX97627.1 - 2.1e-06 27.7 3.1 0.00044 20.3 0.4 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX97627.1 - 0.00021 21.1 1.2 0.079 12.9 0.1 2.7 1 1 2 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX97627.1 - 0.016 15.4 0.3 0.39 10.9 0.1 2.6 1 1 1 2 2 2 0 Rap1 Myb domain Phage_RpbA PF10789.9 EAX97627.1 - 0.018 15.1 0.9 6 7.0 0.1 2.2 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Myb_DNA-bind_4 PF13837.6 EAX97627.1 - 0.64 10.4 5.2 5.8 7.4 0.7 3.2 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain TMP PF05017.14 EAX97629.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Pkinase PF00069.25 EAX97630.1 - 1.4e-50 172.2 0.1 1.7e-50 171.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97630.1 - 1e-33 116.7 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97630.1 - 2.4e-08 33.6 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX97630.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX97630.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EAX97630.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAX97630.1 - 0.04 13.5 0.1 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAX97630.1 - 0.044 12.7 0.1 0.076 11.9 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain DUF1430 PF07242.11 EAX97630.1 - 0.12 12.6 2.3 0.15 12.3 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DHHC PF01529.20 EAX97632.1 - 4.3e-21 75.4 4.6 4.3e-21 75.4 4.6 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase HemY_N PF07219.13 EAX97632.1 - 1.7 8.9 3.2 12 6.2 0.5 2.4 2 0 0 2 2 2 0 HemY protein N-terminus UIM PF02809.20 EAX97633.1 - 0.17 11.9 2.8 0.21 11.6 1.6 1.8 1 1 0 1 1 1 0 Ubiquitin interaction motif OAF PF14941.6 EAX97634.1 - 0.047 13.1 0.2 0.14 11.6 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Pkinase PF00069.25 EAX97635.1 - 2.9e-54 184.2 0.0 4.1e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97635.1 - 1.2e-36 126.4 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97635.1 - 0.00012 21.5 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EAX97635.1 - 0.0017 18.4 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX97635.1 - 0.17 11.5 0.0 2.3 7.8 0.0 2.1 1 1 1 2 2 2 0 RIO1 family Aa_trans PF01490.18 EAX97636.1 - 2.3e-47 161.6 32.0 2.9e-47 161.3 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4107 PF13389.6 EAX97639.1 - 7e-51 172.6 1.5 8.1e-51 172.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAX97642.1 - 0.055 13.5 11.7 0.06 13.3 11.7 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX97642.1 - 1.8 9.0 5.2 2.2 8.7 5.2 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX97643.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX97644.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX97644.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAX97645.1 - 0.085 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4107 PF13389.6 EAX97646.1 - 9.9e-66 220.9 13.1 2.8e-64 216.2 13.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Peptidase_S28 PF05577.12 EAX97650.1 - 1.7e-34 119.4 0.1 2e-34 119.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Nuc_deoxyri_tr2 PF15891.5 EAX97650.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Peptidase_S28 PF05577.12 EAX97651.1 - 4.6e-12 45.5 0.0 5.7e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF4106 PF13388.6 EAX97654.1 - 7.9e-20 71.5 2.3 7.9e-20 71.5 2.3 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) Polysacc_deac_1 PF01522.21 EAX97654.1 - 0.12 12.2 2.4 3.9 7.4 0.6 3.2 2 1 0 2 2 2 0 Polysaccharide deacetylase ArsC PF03960.15 EAX97654.1 - 0.53 10.3 2.5 1.1 9.3 0.1 2.7 2 0 0 2 2 2 0 ArsC family PRA-PH PF01503.17 EAX97655.1 - 0.29 11.6 2.7 13 6.3 3.3 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase LRR_5 PF13306.6 EAX97656.1 - 1.2e-112 371.2 83.2 2.7e-26 92.0 1.7 7.3 3 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97656.1 - 3.5e-22 77.9 25.6 3.5e-05 23.5 0.0 10.1 6 2 7 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EAX97656.1 - 0.0026 18.1 29.6 0.014 15.8 0.1 8.9 6 2 3 10 10 10 2 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAX97656.1 - 1.2 9.3 12.0 1.9 8.7 0.6 4.9 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Beta_helix PF13229.6 EAX97657.1 - 4.8e-09 36.3 46.6 4.5e-07 29.8 13.8 3.3 2 1 1 3 3 3 2 Right handed beta helix region DUF4690 PF15756.5 EAX97657.1 - 0.0003 21.3 0.0 0.00059 20.4 0.0 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Glyco_hydro_47 PF01532.20 EAX97658.1 - 2.4e-108 363.0 5.4 3.2e-108 362.5 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 EAX97658.1 - 0.0047 16.5 2.3 0.059 12.9 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Gly_rich PF12810.7 EAX97659.1 - 3.8e-50 171.1 25.0 5.4e-50 170.6 25.0 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF963 PF06131.11 EAX97660.1 - 0.018 14.5 0.4 0.36 10.3 0.0 3.0 2 1 1 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Phasin_2 PF09361.10 EAX97660.1 - 1.3 9.3 17.3 30 5.0 17.8 2.4 1 1 0 1 1 1 0 Phasin protein Gly_rich PF12810.7 EAX97661.1 - 1.2e-22 81.1 29.9 1.5e-22 80.7 29.9 1.1 1 0 0 1 1 1 1 Glycine rich protein PSP PF04046.16 EAX97662.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX97663.1 - 0.0081 16.1 0.3 0.0081 16.1 0.3 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX97663.1 - 0.028 14.9 3.4 11 7.2 0.2 3.2 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX97664.1 - 1e-30 105.6 11.4 1e-30 105.6 11.4 3.0 5 0 0 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX97664.1 - 2.5 7.7 10.9 0.94 9.0 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX97665.1 - 6.5e-156 516.9 12.8 8.1e-156 516.6 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX97665.1 - 0.11 12.9 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX97665.1 - 1.5 9.4 7.7 1.5 9.3 0.5 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_22 PF13401.6 EAX97666.1 - 4.1e-05 23.9 0.1 0.00026 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX97666.1 - 6.8e-05 22.9 2.7 0.00012 22.1 2.7 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAX97666.1 - 9.2e-05 22.2 0.4 0.32 10.7 0.0 2.8 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX97666.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97666.1 - 0.00075 19.4 0.6 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX97666.1 - 0.0089 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX97666.1 - 0.059 12.8 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX97666.1 - 0.069 13.6 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX97666.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1827 PF08860.10 EAX97666.1 - 0.2 11.9 4.1 6.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX97668.1 - 2.5e-60 202.5 8.6 2.8e-60 202.4 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX97668.1 - 0.11 12.8 0.1 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PRA-PH PF01503.17 EAX97669.1 - 0.027 14.9 1.3 8 7.0 4.2 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase LRR_5 PF13306.6 EAX97670.1 - 1.1e-119 393.9 91.7 8.6e-25 87.2 15.5 8.1 3 2 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97670.1 - 3.3e-22 78.0 16.3 0.0053 16.5 0.4 12.0 9 4 5 14 14 14 6 Leucine rich repeat LRR_4 PF12799.7 EAX97670.1 - 0.0092 16.4 26.7 13 6.4 0.1 9.8 8 3 3 11 11 11 3 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 EAX97670.1 - 0.16 11.7 1.3 15 5.3 0.0 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1699) Exog_C PF18026.1 EAX97671.1 - 0.023 14.8 6.0 0.2 11.7 0.7 2.9 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain bZIP_1 PF00170.21 EAX97671.1 - 0.035 14.2 2.2 0.035 14.2 2.2 2.9 2 1 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 EAX97671.1 - 0.099 11.5 21.4 0.16 10.9 21.3 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF934 PF06073.12 EAX97671.1 - 0.13 12.1 0.5 0.53 10.2 0.1 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF934) DUF2935 PF11155.8 EAX97671.1 - 0.19 12.0 4.9 0.32 11.3 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF3391 PF11871.8 EAX97671.1 - 0.3 11.6 10.0 1.2 9.7 10.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) FlaC_arch PF05377.11 EAX97671.1 - 0.35 11.3 8.9 0.44 11.0 0.3 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SWI-SNF_Ssr4 PF08549.10 EAX97671.1 - 0.4 9.3 8.9 0.45 9.1 8.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF4407 PF14362.6 EAX97671.1 - 0.63 9.3 16.3 0.071 12.5 7.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EAX97671.1 - 1 8.7 21.4 2.1 7.7 21.4 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Prominin PF05478.11 EAX97671.1 - 1.1 7.2 14.1 3.2 5.6 14.1 1.7 1 1 0 1 1 1 0 Prominin UPF0184 PF03670.13 EAX97671.1 - 2 8.8 7.7 0.36 11.3 1.8 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) HTH_40 PF14493.6 EAX97671.1 - 2.5 8.6 14.3 0.048 14.1 3.6 2.8 1 1 2 3 3 3 0 Helix-turn-helix domain Allexi_40kDa PF05549.11 EAX97671.1 - 3.5 7.1 11.0 0.48 9.9 5.3 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein HIP1_clath_bdg PF16515.5 EAX97671.1 - 4.7 7.9 20.5 20 5.8 12.3 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 EAX97671.1 - 5.5 6.5 12.1 7.2 6.1 12.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EAX97671.1 - 5.6 7.2 21.9 0.87 9.8 4.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4404 PF14357.6 EAX97671.1 - 7.9 7.2 17.0 22 5.8 5.4 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 EAX97672.1 - 7e-66 222.3 0.0 2.1e-65 220.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97672.1 - 2.8e-34 118.6 0.0 4.7e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97672.1 - 7.8e-08 32.0 0.0 3.7e-07 29.8 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EAX97672.1 - 6.8e-07 29.4 0.1 0.014 15.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX97672.1 - 0.00016 20.5 0.8 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EAX97672.1 - 0.0025 17.5 2.1 0.71 9.4 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAX97672.1 - 0.0048 16.5 0.1 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EAX97672.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAX97672.1 - 0.046 12.8 0.7 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Viral_Hsp90 PF03225.14 EAX97672.1 - 0.054 12.0 2.9 0.21 10.1 2.9 1.9 1 1 0 1 1 1 0 Viral heat shock protein Hsp90 homologue DUF3939 PF13075.6 EAX97672.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Ribosomal_L21p PF00829.21 EAX97672.1 - 1.3 9.3 3.7 1 9.7 0.0 2.4 3 0 0 3 3 3 0 Ribosomal prokaryotic L21 protein zf-CpG_bind_C PF12269.8 EAX97672.1 - 7.8 6.2 9.4 0.16 11.7 1.9 1.9 2 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain PDEase_I PF00233.19 EAX97674.1 - 2.5e-78 263.1 0.3 2.5e-78 263.1 0.3 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX97674.1 - 2e-48 164.4 0.0 8e-17 62.1 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX97674.1 - 7e-27 94.4 0.0 2.7e-11 43.9 0.0 4.9 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 EAX97674.1 - 2e-20 73.4 0.0 1.5e-07 31.8 0.0 4.2 4 0 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 EAX97674.1 - 9.6e-07 28.9 0.0 0.0043 17.1 0.0 3.1 2 0 0 2 2 2 2 Stage V sporulation protein T C-terminal, transcription factor Pkinase PF00069.25 EAX97675.1 - 4.1e-70 236.2 0.0 5.3e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97675.1 - 7.9e-42 143.3 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97675.1 - 9.6e-12 44.8 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX97675.1 - 3.4e-07 29.6 0.6 6.3e-07 28.7 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAX97675.1 - 9e-06 25.4 0.5 2.3e-05 24.1 0.2 1.7 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EAX97675.1 - 0.0059 15.4 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAX97675.1 - 0.018 15.0 0.0 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX97675.1 - 0.024 14.2 0.3 0.037 13.6 0.3 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAX97675.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAGK_cat PF00781.24 EAX97676.1 - 9.5e-30 102.8 0.0 1.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Fe-ADH_2 PF13685.6 EAX97676.1 - 0.0004 20.2 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NAD_kinase PF01513.21 EAX97676.1 - 0.00057 19.2 0.0 0.00092 18.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase PFK PF00365.20 EAX97676.1 - 0.094 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase RACo_linker PF17650.1 EAX97676.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 RACo linker region Aldedh PF00171.22 EAX97677.1 - 7.8e-77 258.7 0.0 9.3e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAX97677.1 - 0.00075 18.6 0.0 0.0016 17.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ank_2 PF12796.7 EAX97678.1 - 5.1e-35 119.9 1.3 5.1e-12 46.2 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97678.1 - 3.8e-27 94.0 2.0 0.00023 21.4 0.0 7.8 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97678.1 - 2.4e-23 79.7 2.8 0.002 18.5 0.1 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAX97678.1 - 8.1e-20 70.9 4.6 2.7e-06 27.8 0.1 7.3 4 1 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX97678.1 - 1.7e-17 63.0 0.4 0.019 15.4 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat DUF3447 PF11929.8 EAX97678.1 - 1.2e-07 31.6 9.1 3.2e-06 27.0 0.8 4.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) DUF249 PF03158.13 EAX97678.1 - 0.0018 18.0 2.2 3 7.5 0.0 3.7 3 1 1 4 4 4 2 Multigene family 530 protein WASH-7_mid PF14744.6 EAX97680.1 - 4.3e-115 384.5 2.3 7.8e-115 383.7 2.3 1.4 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 EAX97680.1 - 4.3e-56 189.4 2.5 4.3e-56 189.3 0.3 2.2 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 EAX97680.1 - 1.3e-42 146.1 1.8 3.5e-41 141.4 1.8 2.1 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal Ank_4 PF13637.6 EAX97681.1 - 7.2e-19 67.9 1.9 4.3e-14 52.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97681.1 - 1.7e-17 63.3 3.4 5.3e-12 45.7 0.9 2.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97681.1 - 2.5e-17 62.4 0.7 8.1e-07 29.2 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX97681.1 - 1.7e-16 60.6 0.6 2.2e-16 60.2 0.6 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97681.1 - 4.8e-14 51.1 1.5 1.3e-05 25.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF3427 PF11907.8 EAX97681.1 - 0.028 13.7 0.9 0.044 13.1 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3427) MAP65_ASE1 PF03999.12 EAX97683.1 - 4.1e-16 58.8 22.8 4.1e-16 58.8 22.8 4.8 2 1 2 5 5 5 3 Microtubule associated protein (MAP65/ASE1 family) ApoO PF09769.9 EAX97683.1 - 0.71 9.8 0.0 0.71 9.8 0.0 2.9 3 0 0 3 3 3 0 Apolipoprotein O YlbE PF14003.6 EAX97683.1 - 1.1 9.7 4.1 13 6.4 0.6 3.3 2 0 0 2 2 2 0 YlbE-like protein MerR-DNA-bind PF09278.11 EAX97683.1 - 1.9 9.1 5.7 8.8 6.9 0.0 3.8 3 0 0 3 3 3 0 MerR, DNA binding DUF4108 PF13390.6 EAX97684.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ly49 PF08391.10 EAX97685.1 - 0.29 11.5 2.5 0.58 10.5 2.5 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pox_A32 PF04665.12 EAX97686.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX97686.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX97686.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX97686.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97686.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97686.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX97686.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97686.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX97686.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX97686.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX97686.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX97686.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX97686.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX97687.1 - 1.1e-41 141.2 1.1 1.6e-41 140.7 0.2 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX97687.1 - 0.014 16.0 0.1 0.04 14.5 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family T5orf172 PF10544.9 EAX97688.1 - 6.2e-06 26.7 0.2 1.5e-05 25.5 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX97688.1 - 0.0024 17.7 0.2 0.02 14.7 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX97688.1 - 0.023 14.2 0.3 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 Legume lectin domain DUF3839 PF12943.7 EAX97689.1 - 6.8e-26 91.2 4.9 1.1e-25 90.5 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX97689.1 - 0.029 14.7 0.4 0.095 13.0 0.1 1.9 1 1 1 2 2 2 0 PRD domain DUF1493 PF07377.12 EAX97691.1 - 0.089 13.3 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX97692.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97693.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX97694.1 - 4.6e-27 95.0 0.0 6.8e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97694.1 - 1.1e-21 77.3 0.0 2.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EAX97694.1 - 3.1e-15 56.5 0.1 2.2e-14 53.8 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97694.1 - 2.1e-12 47.3 0.0 3.2e-07 30.8 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97694.1 - 2e-11 43.1 0.1 6.4e-05 23.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX97694.1 - 2.1e-11 43.8 0.0 7e-06 26.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97694.1 - 1.4e-07 31.6 0.0 0.0032 17.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat YukC PF10140.9 EAX97694.1 - 0.047 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Ish1 PF10281.9 EAX97694.1 - 0.066 13.5 0.0 0.75 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein tRNA_anti_2 PF13742.6 EAX97695.1 - 0.02 15.1 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF4218 PF13960.6 EAX97695.1 - 0.074 12.7 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) MFS_1 PF07690.16 EAX97696.1 - 0.15 11.0 10.8 0.025 13.5 7.3 1.4 2 0 0 2 2 2 0 Major Facilitator Superfamily RabGAP-TBC PF00566.18 EAX97697.1 - 9.5e-12 45.0 6.3 1.4e-11 44.4 6.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FliL PF03748.14 EAX97697.1 - 0.073 13.7 0.2 0.21 12.2 0.2 1.8 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL CBM_6 PF03422.15 EAX97698.1 - 0.0079 16.5 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) ABC_membrane PF00664.23 EAX97699.1 - 3.1e-43 148.4 9.8 4.2e-43 148.0 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAX97699.1 - 8.6e-36 123.5 0.0 1.5e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX97699.1 - 4.1e-05 23.1 3.2 0.0017 17.9 0.4 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAX97699.1 - 0.00017 21.4 0.6 0.00027 20.8 0.1 1.6 2 0 0 2 2 1 1 AAA ATPase domain DUF87 PF01935.17 EAX97699.1 - 0.00031 20.9 0.1 0.00058 20.0 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 EAX97699.1 - 0.00063 19.1 0.0 0.0027 17.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 EAX97699.1 - 0.001 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX97699.1 - 0.0014 18.9 0.1 0.0058 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAX97699.1 - 0.0049 16.6 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EAX97699.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Sas10_Utp3 PF04000.15 EAX97699.1 - 0.0094 16.6 0.1 0.03 14.9 0.1 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2075 PF09848.9 EAX97699.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EAX97699.1 - 0.034 14.6 0.7 0.42 11.0 0.7 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ACR_tran PF00873.19 EAX97699.1 - 0.034 11.8 0.6 0.056 11.1 0.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RsgA_GTPase PF03193.16 EAX97699.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase OstA_2 PF13100.6 EAX97699.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 OstA-like protein OppC_N PF12911.7 EAX97699.1 - 1.9 8.5 5.3 29 4.7 0.5 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C CDC50 PF03381.15 EAX97701.1 - 1e-37 130.2 5.0 1.4e-37 129.8 5.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CNP1 PF08750.11 EAX97701.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 CNP1-like family ATP_transf PF09830.9 EAX97702.1 - 5.9e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EAX97702.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) V-SNARE_C PF12352.8 EAX97703.1 - 1.2e-05 25.5 0.6 1.6e-05 25.1 0.6 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EAX97703.1 - 0.0081 16.0 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Sec20 SHE3 PF17078.5 EAX97703.1 - 0.059 13.1 0.4 0.074 12.8 0.4 1.0 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PA14 PF07691.12 EAX97704.1 - 5.4e-06 26.3 0.7 8.3e-06 25.7 0.7 1.3 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EAX97704.1 - 0.0033 17.8 1.4 0.006 17.0 0.3 2.0 2 1 0 2 2 2 1 GLEYA domain GLEYA PF10528.9 EAX97705.1 - 0.039 14.4 0.8 0.039 14.4 0.8 1.7 2 0 0 2 2 2 0 GLEYA domain Ank_2 PF12796.7 EAX97706.1 - 1.6e-19 70.3 0.6 1.6e-11 44.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97706.1 - 1.7e-15 55.6 0.5 0.032 14.8 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EAX97706.1 - 1.2e-13 50.8 0.4 1.8e-05 24.9 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX97706.1 - 2.7e-13 50.1 0.0 3.8e-05 24.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97706.1 - 1e-08 35.3 0.1 0.021 15.1 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97706.1 - 0.002 18.1 3.3 0.09 12.7 0.4 3.3 1 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97707.1 - 5.7e-24 84.5 0.1 6.7e-08 33.0 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97707.1 - 1.5e-18 66.6 0.0 2.2e-08 34.2 0.0 4.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97707.1 - 1.7e-18 66.7 0.1 4.1e-07 30.4 0.0 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EAX97707.1 - 1.4e-17 63.8 0.0 2.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 EAX97707.1 - 9.3e-15 54.3 0.0 0.0021 18.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX97707.1 - 7.6e-14 50.5 0.1 7.3e-05 22.9 0.0 7.1 6 0 0 6 6 6 2 Ankyrin repeat Pkinase PF00069.25 EAX97707.1 - 9.8e-12 44.8 0.0 3.1e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain ETRAMP PF09716.10 EAX97708.1 - 0.006 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Fusion_gly PF00523.18 EAX97708.1 - 0.011 14.0 0.1 0.016 13.5 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 PTR PF12789.7 EAX97711.1 - 2.1e-12 46.9 28.1 3.5e-08 33.4 5.1 5.0 5 0 0 5 5 5 3 Phage tail repeat like Collagen PF01391.18 EAX97711.1 - 1.7e-06 27.7 12.2 3.1e-06 26.9 12.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) UPF0242 PF06785.11 EAX97711.1 - 0.035 14.2 5.1 0.039 14.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 EAX97711.1 - 8.3 6.4 9.2 34 4.5 0.1 4.1 3 1 1 4 4 4 0 Laminin Domain II DUF3839 PF12943.7 EAX97714.1 - 3.5e-103 344.2 7.4 4.1e-103 344.0 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Ank_2 PF12796.7 EAX97715.1 - 9.3e-37 125.5 6.4 9.4e-19 67.8 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97715.1 - 7.1e-27 93.4 1.1 2.9e-11 43.7 0.1 5.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97715.1 - 4.8e-21 74.5 0.6 3.4e-10 40.0 0.2 5.8 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97715.1 - 1.3e-20 71.3 0.4 1.1e-05 25.4 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EAX97715.1 - 9.5e-16 57.5 0.1 1.1e-05 25.7 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAX97715.1 - 2.2e-07 30.7 18.3 2.8e-06 27.2 0.5 4.6 2 1 3 5 5 5 3 Domain of unknown function (DUF3447) Phage_T7_Capsid PF05396.11 EAX97715.1 - 0.029 14.7 0.1 0.99 9.8 0.1 2.9 3 1 2 5 5 5 0 Phage T7 capsid assembly protein DBD_Tnp_Hermes PF10683.9 EAX97715.1 - 0.039 13.6 0.2 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain DUF4616 PF15394.6 EAX97715.1 - 0.07 12.1 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) LRR_6 PF13516.6 EAX97716.1 - 0.2 11.8 0.1 0.43 10.8 0.1 1.6 1 0 0 1 1 1 0 Leucine Rich repeat LRR_4 PF12799.7 EAX97716.1 - 0.57 10.7 6.6 1.2 9.7 0.2 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TraF PF13728.6 EAX97717.1 - 0.0001 22.2 1.1 0.00022 21.1 0.6 1.8 2 0 0 2 2 2 1 F plasmid transfer operon protein RNA_pol_Rpc82 PF05645.13 EAX97717.1 - 0.035 13.9 3.9 0.076 12.8 3.9 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF848 PF05852.11 EAX97717.1 - 6.6 6.8 8.5 27 4.8 1.9 2.9 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) RICTOR_M PF14666.6 EAX97718.1 - 0.08 12.7 0.1 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain bZIP_1 PF00170.21 EAX97719.1 - 0.051 13.7 14.5 0.43 10.7 0.3 4.7 3 1 1 4 4 4 0 bZIP transcription factor SSXT PF05030.12 EAX97719.1 - 0.074 12.7 1.7 0.43 10.2 0.0 2.8 3 0 0 3 3 3 0 SSXT protein (N-terminal region) bZIP_2 PF07716.15 EAX97719.1 - 0.12 12.5 0.1 0.12 12.5 0.1 4.5 4 0 0 4 4 4 0 Basic region leucine zipper Lectin_N PF03954.14 EAX97719.1 - 1.6 8.5 6.7 9.9 5.9 0.7 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Syja_N PF02383.18 EAX97719.1 - 1.6 8.0 5.9 0.15 11.4 1.2 1.7 2 0 0 2 2 2 0 SacI homology domain ECH_2 PF16113.5 EAX97719.1 - 2.9 7.3 9.5 0.31 10.5 1.9 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Spectrin PF00435.21 EAX97719.1 - 4.9 7.7 14.3 0.67 10.5 3.6 3.2 3 0 0 3 3 3 0 Spectrin repeat PilO PF04350.13 EAX97719.1 - 5.2 7.2 9.4 0.17 12.0 0.9 2.7 3 0 0 3 3 3 0 Pilus assembly protein, PilO Ank_2 PF12796.7 EAX97720.1 - 2.9e-11 43.8 0.1 3.2e-08 34.0 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97720.1 - 6.3e-07 29.6 0.1 0.0023 18.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX97720.1 - 1.5e-06 28.1 0.2 0.069 13.7 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAX97720.1 - 3.6e-05 24.2 0.1 0.47 11.1 0.0 4.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97720.1 - 0.00076 19.7 0.0 0.37 11.2 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97721.1 - 2.3e-09 37.1 1.2 7e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97721.1 - 0.0031 18.0 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_aberr PF17017.5 EAX97721.1 - 0.02 15.1 0.2 0.033 14.3 0.2 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger Borrelia_P83 PF05262.11 EAX97722.1 - 1.8e-06 26.8 15.9 1.9e-06 26.6 15.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein CRT10 PF08728.10 EAX97722.1 - 0.044 12.0 9.5 0.048 11.8 9.5 1.2 1 0 0 1 1 1 0 CRT10 MAJIN PF15077.6 EAX97722.1 - 0.13 12.0 17.3 0.21 11.3 17.3 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Reticulon PF02453.17 EAX97722.1 - 0.41 10.6 9.4 0.69 9.9 9.4 1.3 1 0 0 1 1 1 0 Reticulon Apt1 PF10351.9 EAX97722.1 - 1.8 7.3 22.9 2.5 6.9 22.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CLN3 PF02487.17 EAX97722.1 - 4.8 6.1 28.3 1.5e+03 -2.1 28.3 2.2 1 1 0 1 1 1 0 CLN3 protein LicD PF04991.13 EAX97722.1 - 7.6 6.6 18.3 13 5.9 18.3 1.3 1 0 0 1 1 1 0 LicD family MDM10 PF12519.8 EAX97722.1 - 8.4 5.1 24.4 12 4.6 24.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PCI PF01399.27 EAX97723.1 - 0.0077 16.7 2.0 0.01 16.3 2.0 1.2 1 0 0 1 1 1 1 PCI domain Fmp27_WPPW PF10359.9 EAX97723.1 - 0.015 14.2 6.0 0.018 13.9 6.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.8 EAX97723.1 - 0.017 15.1 11.5 0.031 14.3 2.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EAX97723.1 - 0.027 14.9 13.5 0.096 13.1 0.4 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Com_YlbF PF06133.11 EAX97723.1 - 0.099 13.3 10.0 0.15 12.7 9.4 1.6 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA YabA PF06156.13 EAX97723.1 - 0.17 12.6 6.6 0.45 11.2 6.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Rho_Binding PF08912.11 EAX97723.1 - 2.5 9.0 11.9 2.7 8.9 1.9 2.1 1 1 1 2 2 2 0 Rho Binding Ank PF00023.30 EAX97724.1 - 4.5e-17 61.6 1.2 3e-08 33.7 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX97724.1 - 5.6e-17 62.1 1.0 7e-17 61.8 1.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97724.1 - 3.8e-15 56.0 1.0 8.2e-12 45.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97724.1 - 7.6e-15 53.6 0.7 1.9e-07 30.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX97724.1 - 2.2e-12 46.9 1.1 2.8e-12 46.6 0.6 1.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAX97724.1 - 0.024 14.4 0.2 0.029 14.1 0.2 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein Mic1 PF07035.12 EAX97724.1 - 0.03 14.0 0.0 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like DDR PF08841.10 EAX97728.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX97730.1 - 0.015 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Spore_coat_CotO PF14153.6 EAX97730.1 - 0.27 11.1 10.2 0.42 10.5 10.0 1.4 1 1 0 1 1 1 0 Spore coat protein CotO DUF2939 PF11159.8 EAX97731.1 - 0.02 15.3 0.5 0.026 14.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) LpoB PF13036.6 EAX97731.1 - 0.021 14.7 2.1 0.027 14.4 2.1 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Membralin PF09746.9 EAX97731.1 - 1.1 8.3 3.0 1 8.3 3.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX97731.1 - 1.6 8.7 5.8 1.7 8.6 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX97732.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) T5orf172 PF10544.9 EAX97733.1 - 8e-06 26.3 0.2 1.9e-05 25.1 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX97733.1 - 0.01 15.7 0.2 0.053 13.4 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAX97733.1 - 0.029 13.9 0.7 0.69 9.4 0.2 2.0 2 0 0 2 2 2 0 Legume lectin domain Amidase02_C PF12123.8 EAX97734.1 - 0.0024 17.5 0.0 0.0069 16.0 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAX97734.1 - 0.21 11.5 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAX97735.1 - 1.4e-73 246.4 3.9 1.7e-73 246.1 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX97735.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Herpes_IE2_3 PF03361.14 EAX97738.1 - 0.019 14.8 1.1 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Toxin_R_bind_C PF07951.12 EAX97738.1 - 0.027 14.1 4.9 0.053 13.2 0.6 2.5 2 1 1 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding HEAT PF02985.22 EAX97738.1 - 0.059 13.7 0.1 1.3 9.5 0.0 3.1 4 0 0 4 4 4 0 HEAT repeat PPP5 PF08321.12 EAX97738.1 - 0.25 11.7 8.3 1.5 9.2 0.8 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region ARA70 PF12489.8 EAX97739.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Glyco_hydro_14 PF01373.17 EAX97740.1 - 7.3e-89 298.5 10.7 8.2e-89 298.3 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 NdhS PF11623.8 EAX97740.1 - 0.055 13.1 0.3 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H dehydrogenase subunit S Ank_2 PF12796.7 EAX97741.1 - 7e-77 254.1 40.8 1.8e-15 57.3 0.2 7.8 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97741.1 - 1.1e-62 205.9 22.9 1.8e-06 28.1 0.5 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 EAX97741.1 - 3.1e-60 199.8 32.2 3.3e-10 40.3 0.0 10.9 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97741.1 - 1.2e-53 172.8 26.0 2.9e-05 24.1 0.0 12.4 13 0 0 13 13 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX97741.1 - 1.8e-51 171.5 18.5 2.3e-07 31.0 0.3 8.5 2 1 6 9 9 9 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97741.1 - 3.9e-28 97.2 6.4 3.9e-28 97.2 6.4 6.3 5 2 2 8 8 7 2 Domain of unknown function (DUF3447) TPP_enzyme_C PF02775.21 EAX97741.1 - 0.0015 18.3 0.0 0.18 11.6 0.1 3.0 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MetallophosN PF16371.5 EAX97741.1 - 0.0039 17.4 1.2 2.7 8.3 0.1 4.4 2 1 2 4 4 4 1 N terminal of Calcineurin-like phosphoesterase DrsE PF02635.15 EAX97741.1 - 0.028 14.8 0.9 0.096 13.1 0.1 2.4 2 1 1 3 3 3 0 DsrE/DsrF-like family Tom37 PF10568.9 EAX97741.1 - 0.079 13.3 0.9 7.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein CCDC84 PF14968.6 EAX97741.1 - 0.16 11.6 0.9 0.4 10.3 0.7 1.9 2 0 0 2 2 2 0 Coiled coil protein 84 LRR_5 PF13306.6 EAX97742.1 - 8.5e-29 100.1 36.9 1.5e-17 63.7 24.1 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97742.1 - 3.7e-07 29.8 8.1 0.01 15.6 0.1 4.3 3 1 2 5 5 5 4 Leucine rich repeat MecA PF05389.12 EAX97742.1 - 0.00041 20.1 1.5 0.0006 19.5 1.5 1.2 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) LRR_5 PF13306.6 EAX97743.1 - 8.3e-62 206.8 28.5 9.5e-29 100.0 7.6 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97743.1 - 1e-10 41.2 0.1 1.1e-05 25.1 0.1 5.1 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EAX97743.1 - 0.0014 19.0 0.7 0.012 16.1 0.2 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Hexapep_2 PF14602.6 EAX97743.1 - 0.48 10.2 2.7 2.7 7.8 1.6 2.9 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Beach PF02138.18 EAX97744.1 - 5e-102 341.0 5.3 6.8e-102 340.5 5.3 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX97744.1 - 0.0014 18.7 0.2 0.0042 17.2 0.2 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EAX97744.1 - 0.022 15.6 0.2 0.14 13.1 0.2 2.5 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4704 PF15787.5 EAX97745.1 - 1.6e-06 27.6 0.4 1.6e-06 27.6 0.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) DUF5611 PF18446.1 EAX97745.1 - 0.18 12.7 0.2 1.4 9.9 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5611) UNC45-central PF11701.8 EAX97745.1 - 0.38 10.7 3.6 2.5 8.0 0.1 3.8 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Myb_DNA-binding PF00249.31 EAX97746.1 - 3e-27 94.5 1.8 2.4e-15 56.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97746.1 - 5.6e-23 81.0 0.4 3.4e-12 46.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX97746.1 - 0.00061 19.6 2.6 0.024 14.5 0.6 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAX97746.1 - 0.0011 19.2 0.1 0.43 10.8 0.1 2.8 2 1 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EAX97746.1 - 0.0043 17.0 0.2 1.2 9.2 0.0 2.7 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 EAX97746.1 - 0.0044 17.1 0.1 0.057 13.5 0.1 2.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EAX97746.1 - 0.031 14.5 0.8 1.3 9.2 0.2 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Ras PF00071.22 EAX97747.1 - 1.7e-36 125.3 0.0 2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX97747.1 - 1.4e-26 93.0 0.0 1.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX97747.1 - 8.9e-14 51.3 0.0 9.7e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX97747.1 - 4e-06 26.9 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAX97747.1 - 3.5e-05 23.8 0.2 0.002 18.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EAX97747.1 - 0.005 16.3 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IIGP PF05049.13 EAX97747.1 - 0.0056 15.8 0.1 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 EAX97747.1 - 0.018 14.6 0.0 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 EAX97747.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TusA PF01206.17 EAX97747.1 - 0.044 13.6 0.0 0.73 9.7 0.0 2.4 3 0 0 3 3 3 0 Sulfurtransferase TusA DsbC_N PF10411.9 EAX97747.1 - 0.047 13.1 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus AAA_16 PF13191.6 EAX97747.1 - 0.055 13.9 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EAX97747.1 - 0.086 13.4 0.2 0.17 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAX97747.1 - 0.11 12.2 0.7 1.9 8.2 0.1 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EAX97747.1 - 0.21 11.0 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ran_BP1 PF00638.18 EAX97748.1 - 3e-09 37.2 0.2 1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 EAX97748.1 - 0.021 14.7 0.1 0.58 10.1 0.0 2.5 2 1 0 2 2 2 0 WH1 domain LRR_5 PF13306.6 EAX97750.1 - 1.2e-11 44.7 0.1 2e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX97751.1 - 4.1e-09 36.5 0.2 6.3e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DHC_N1 PF08385.12 EAX97752.1 - 0.036 12.7 2.1 0.053 12.2 1.3 1.6 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF4472 PF14739.6 EAX97752.1 - 0.14 12.9 10.8 0.33 11.7 10.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) FapA PF03961.13 EAX97752.1 - 0.72 8.4 4.6 1.3 7.6 4.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 EAX97752.1 - 1.6 7.9 4.0 2.5 7.3 4.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein Cnn_1N PF07989.11 EAX97752.1 - 2.3 8.4 11.7 1.6 8.9 5.9 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Exonuc_VII_L PF02601.15 EAX97752.1 - 3.8 7.0 5.5 5.8 6.4 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.6 EAX97752.1 - 4.7 6.8 14.4 0.94 9.1 9.1 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 EAX97752.1 - 6.5 6.0 8.1 13 5.0 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) LRR_5 PF13306.6 EAX97753.1 - 4.5e-91 301.5 84.5 2.6e-19 69.5 1.4 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97753.1 - 6.3e-17 61.1 10.3 0.0084 15.9 0.0 9.9 6 2 5 11 11 11 6 Leucine rich repeat MecA PF05389.12 EAX97753.1 - 0.0013 18.5 1.8 0.0024 17.5 1.8 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) LRR_4 PF12799.7 EAX97753.1 - 0.25 11.8 15.6 2.4 8.7 0.1 6.8 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) RepB PF07506.11 EAX97754.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RepB plasmid partitioning protein ORC5_C PF14630.6 EAX97755.1 - 9.9e-13 48.2 1.3 3.2e-10 40.0 0.2 2.8 1 1 0 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA PF00004.29 EAX97755.1 - 0.00012 22.5 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX97755.1 - 0.00041 20.8 0.0 0.12 12.8 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAX97755.1 - 0.00078 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAX97755.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 EAX97755.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EAX97755.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX97755.1 - 0.053 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EAX97755.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EAX97755.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Band_7_1 PF13421.6 EAX97756.1 - 1.3 8.6 4.8 0.35 10.5 0.6 2.2 2 0 0 2 2 2 0 SPFH domain-Band 7 family PAP_assoc PF03828.19 EAX97757.1 - 8.6e-12 45.1 0.2 1.9e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAX97757.1 - 2.3e-05 24.6 0.0 0.00014 22.1 0.0 2.1 1 1 1 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAX97757.1 - 0.00062 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HMG_box PF00505.19 EAX97759.1 - 1.2e-14 54.4 0.8 1.7e-12 47.5 1.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX97759.1 - 8.1e-08 32.7 2.0 1.3e-07 32.1 2.0 1.2 1 0 0 1 1 1 1 HMG-box domain IL1_propep PF02394.16 EAX97759.1 - 0.033 15.1 0.2 0.049 14.6 0.2 1.2 1 0 0 1 1 1 0 Interleukin-1 propeptide NOT2_3_5 PF04153.18 EAX97760.1 - 3.3e-16 59.6 8.3 6.9e-16 58.5 8.3 1.7 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Thioredoxin PF00085.20 EAX97761.1 - 1.5e-17 63.4 0.0 3.5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAX97761.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EAX97761.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Coat_X PF07552.11 EAX97762.1 - 0.073 12.9 0.3 0.073 12.9 0.3 1.5 2 0 0 2 2 2 0 Spore Coat Protein X and V domain Bud13 PF09736.9 EAX97763.1 - 2e-15 57.4 11.0 3.3e-15 56.8 10.8 1.5 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex LRR_5 PF13306.6 EAX97764.1 - 1.6e-118 390.2 104.1 3.7e-26 91.6 13.1 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97764.1 - 4.5e-18 64.8 14.0 2.4e-05 24.0 0.3 10.3 8 3 5 13 13 13 7 Leucine rich repeat MecA PF05389.12 EAX97764.1 - 0.00038 20.2 2.3 0.00074 19.2 2.3 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) LRR_4 PF12799.7 EAX97764.1 - 0.0021 18.4 18.1 0.12 12.8 0.2 7.6 8 0 0 8 8 8 2 Leucine Rich repeats (2 copies) Peptidase_M60_C PF18630.1 EAX97764.1 - 0.016 15.3 1.4 7.4 6.8 0.1 4.3 4 0 0 4 4 4 0 Peptidase M60 C-terminal domain Microcin PF03526.13 EAX97764.1 - 2 8.3 0.0 2 8.3 0.0 5.0 6 0 0 6 6 6 0 Colicin E1 (microcin) immunity protein LRR_5 PF13306.6 EAX97765.1 - 1.1e-116 384.3 106.7 4.7e-26 91.2 12.7 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97765.1 - 1.1e-18 66.7 11.4 1e-05 25.2 0.3 10.2 6 2 6 12 12 12 6 Leucine rich repeat MecA PF05389.12 EAX97765.1 - 0.00034 20.3 2.3 0.00066 19.4 2.3 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) LRR_4 PF12799.7 EAX97765.1 - 0.003 17.9 17.6 0.033 14.6 0.5 7.2 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX97766.1 - 2.5e-35 121.2 24.7 2.6e-30 105.0 11.8 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97766.1 - 3.5e-09 36.3 3.3 1.3e-06 28.1 0.3 3.7 1 1 3 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EAX97766.1 - 0.0094 16.3 1.6 0.0094 16.3 1.6 3.0 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX97766.1 - 0.57 10.9 3.6 9.2 7.3 0.1 3.5 2 2 0 2 2 2 0 Leucine Rich Repeat AlaDh_PNT_N PF05222.15 EAX97767.1 - 8.1e-34 116.8 0.0 8.8e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EAX97768.1 - 4.7e-73 245.0 0.0 5.5e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EAX97768.1 - 2.2e-05 23.9 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAX97768.1 - 4.4e-05 23.6 0.0 6.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EAX97768.1 - 0.00098 18.5 1.7 0.028 13.8 1.0 2.6 2 1 1 3 3 3 1 ThiF family THF_DHG_CYH_C PF02882.19 EAX97768.1 - 0.00099 18.5 0.0 0.11 11.8 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EAX97768.1 - 0.0016 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EAX97768.1 - 0.0096 16.3 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EAX97768.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2534 PF10749.9 EAX97768.1 - 0.025 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Sacchrp_dh_NADP PF03435.18 EAX97768.1 - 0.03 14.6 0.0 0.089 13.1 0.0 1.8 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 EAX97768.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.22 EAX97768.1 - 0.036 13.1 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EAX97768.1 - 0.065 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAX97768.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAX97768.1 - 0.12 11.6 2.1 0.17 11.2 2.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EAX97768.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EAX97768.1 - 0.16 10.7 0.3 0.21 10.2 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Gly_rich PF12810.7 EAX97769.1 - 3.4e-16 59.9 11.1 4.6e-16 59.5 11.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Peptidase_M1 PF01433.20 EAX97770.1 - 0.11 12.0 0.0 5.7 6.4 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M1 domain BLF1 PF17752.1 EAX97770.1 - 0.12 11.6 0.0 5.6 6.2 0.0 2.1 1 1 1 2 2 2 0 Burkholderia lethal factor 1 Gly_rich PF12810.7 EAX97771.1 - 1e-30 107.5 25.4 1.3e-30 107.1 25.4 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX97772.1 - 1.3e-23 84.2 24.1 1.5e-23 84.0 24.1 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4625 PF15418.6 EAX97773.1 - 2.1e-07 31.3 11.9 0.63 10.3 0.1 7.2 4 3 1 5 5 5 4 Domain of unknown function (DUF4625) Cadherin PF00028.17 EAX97773.1 - 0.00079 19.8 3.4 1.3 9.5 0.1 4.9 4 0 0 4 4 4 1 Cadherin domain FKBP_N_2 PF18023.1 EAX97773.1 - 0.0079 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 BDBT FKBP like N-terminal Shisa PF13908.6 EAX97773.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 EAX97773.1 - 0.037 13.9 0.1 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Amnionless PF14828.6 EAX97773.1 - 0.061 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 EAX97773.1 - 0.062 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Y_Y_Y PF07495.13 EAX97773.1 - 0.067 13.2 14.8 0.34 10.9 0.2 6.0 6 0 0 6 6 5 0 Y_Y_Y domain EphA2_TM PF14575.6 EAX97773.1 - 0.13 13.1 0.0 0.44 11.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 EAX97773.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Rifin GBS_Bsp-like PF08481.10 EAX97773.1 - 0.21 11.7 2.3 5.5 7.2 0.3 3.3 2 0 0 2 2 2 0 GBS Bsp-like repeat DUF4834 PF16118.5 EAX97773.1 - 0.45 11.5 3.9 0.37 11.8 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 EAX97773.1 - 1.7 8.6 5.2 8.4 6.3 5.2 2.2 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TA0956 PF11513.8 EAX97774.1 - 0.064 13.5 0.4 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 Haem_degrading PF03928.14 EAX97775.1 - 1.1e-24 86.8 0.1 1.2e-24 86.6 0.1 1.0 1 0 0 1 1 1 1 Haem-degrading Ras PF00071.22 EAX97776.1 - 8.5e-34 116.5 0.0 1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX97776.1 - 3.3e-26 91.8 0.0 4.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX97776.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX97776.1 - 2.5e-05 23.9 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX97776.1 - 8.2e-05 22.6 0.2 0.15 12.0 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX97776.1 - 0.00028 20.4 0.0 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX97776.1 - 0.00098 19.2 0.0 0.0014 18.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX97776.1 - 0.0067 16.2 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation HSP90 PF00183.18 EAX97776.1 - 0.034 13.1 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Gly_rich PF12810.7 EAX97777.1 - 1.2e-20 74.4 18.1 1.4e-20 74.3 18.1 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX97779.1 - 2.1e-09 37.4 10.7 4.5e-09 36.4 8.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF3915 PF13054.6 EAX97779.1 - 0.12 12.4 3.2 0.22 11.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DHC_N2 PF08393.13 EAX97780.1 - 5.2e-29 101.6 13.7 5.2e-29 101.6 13.7 5.4 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 DUF5497 PF17601.2 EAX97780.1 - 6.3 7.2 8.9 7 7.0 0.6 4.2 3 0 0 3 3 3 0 Family of unknown function (DUF5497) BLOC1_2 PF10046.9 EAX97783.1 - 0.0049 17.2 1.5 0.0089 16.3 1.5 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_Prp PF04327.12 EAX97783.1 - 0.028 14.6 0.2 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 Cysteine protease Prp DUF1691 PF07950.11 EAX97783.1 - 0.18 12.5 0.0 0.56 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) ACP_PD PF04336.12 EAX97784.1 - 0.03 14.7 0.1 1.1 9.7 0.0 3.3 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase T5orf172 PF10544.9 EAX97785.1 - 1.3e-06 28.8 0.3 3.4e-06 27.6 0.3 1.7 1 1 0 1 1 1 1 T5orf172 domain DUF3839 PF12943.7 EAX97786.1 - 2.6e-157 521.5 13.2 3.2e-157 521.2 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX97786.1 - 3 8.4 6.7 3.3 8.2 0.2 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAX97788.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97789.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP SRP19 PF01922.17 EAX97790.1 - 6.7e-23 81.5 0.0 1.1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Npa1 PF11707.8 EAX97791.1 - 0.00039 19.9 5.5 0.09 12.1 0.1 3.2 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal DUF577 PF04510.12 EAX97791.1 - 0.00053 19.9 4.1 0.00063 19.7 0.1 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF577) HEAT_2 PF13646.6 EAX97791.1 - 0.0027 18.1 0.3 9.9 6.6 0.0 5.2 5 2 1 6 6 6 1 HEAT repeats HEAT PF02985.22 EAX97791.1 - 0.0044 17.2 1.0 6.5 7.3 0.0 5.0 5 0 0 5 5 3 1 HEAT repeat RIX1 PF08167.12 EAX97791.1 - 0.0097 15.7 5.6 0.21 11.3 0.2 4.5 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EAX97791.1 - 0.045 13.7 3.9 0.36 10.8 0.0 4.2 4 1 1 5 5 5 0 Importin-beta N-terminal domain DUF3924 PF13062.6 EAX97791.1 - 0.064 13.2 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Condensin2nSMC PF12422.8 EAX97791.1 - 0.24 11.6 5.8 11 6.1 0.0 4.1 3 1 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit RTP1_C1 PF10363.9 EAX97791.1 - 0.38 10.9 6.1 2.2 8.5 0.1 4.4 6 1 0 6 6 5 0 Required for nuclear transport of RNA pol II C-terminus 1 ESCRT-II PF05871.12 EAX97791.1 - 1.1 9.5 4.2 1.3 9.3 1.5 2.4 2 0 0 2 2 2 0 ESCRT-II complex subunit CNOT11 PF10155.9 EAX97791.1 - 2 8.6 6.1 5.6 7.1 1.8 3.6 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 Cnd1 PF12717.7 EAX97791.1 - 3.9 7.5 29.2 0.028 14.5 2.1 5.8 5 2 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EAX97791.1 - 5.9 6.8 21.9 0.36 10.8 0.5 5.2 3 1 2 6 6 6 0 Domain of unknown function (DUF3361) DUF1664 PF07889.12 EAX97792.1 - 0.019 15.0 3.1 0.019 15.0 3.1 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Trans_reg_C PF00486.28 EAX97792.1 - 0.046 13.8 3.6 2.2 8.4 0.0 4.0 5 0 0 5 5 5 0 Transcriptional regulatory protein, C terminal Filament PF00038.21 EAX97792.1 - 0.14 11.7 44.5 0.051 13.1 13.0 4.0 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 EAX97792.1 - 0.3 9.9 49.4 0.05 12.5 5.9 4.3 1 1 1 4 4 4 0 Spc7 kinetochore protein YojJ PF10372.9 EAX97792.1 - 1.4 9.0 9.6 8.5 6.5 0.3 3.5 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Sec20 PF03908.13 EAX97792.1 - 7 6.6 8.4 3.8 7.5 1.2 3.6 3 1 1 4 4 4 0 Sec20 TSC22 PF01166.18 EAX97792.1 - 8.7 6.7 14.8 36 4.7 0.3 5.6 4 1 0 4 4 4 0 TSC-22/dip/bun family MSC PF09402.10 EAX97793.1 - 8.6e-06 25.4 2.9 0.022 14.2 0.1 2.5 1 1 1 2 2 2 2 Man1-Src1p-C-terminal domain FF PF01846.19 EAX97793.1 - 0.00031 20.8 1.4 0.011 15.9 0.2 3.0 3 0 0 3 3 3 1 FF domain HTH_6 PF01418.17 EAX97793.1 - 0.0036 17.3 1.1 1 9.4 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain, rpiR family DUF485 PF04341.12 EAX97793.1 - 0.042 13.8 0.4 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Baculo_11_kDa PF06143.11 EAX97793.1 - 0.056 13.0 1.8 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1201 PF06716.11 EAX97793.1 - 0.24 11.4 4.8 6.3 6.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Steroid_dh PF02544.16 EAX97794.1 - 1.4e-27 96.5 6.1 1.4e-27 96.5 6.1 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EAX97794.1 - 5.5e-05 22.8 0.2 9.8e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) YukC PF10140.9 EAX97794.1 - 2.4 6.9 5.0 0.23 10.3 0.2 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Arm-DNA-bind_5 PF17293.2 EAX97795.1 - 0.017 15.5 1.0 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Arm DNA-binding domain APOBEC4_like PF18774.1 EAX97795.1 - 0.048 13.6 0.7 0.095 12.6 0.7 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Pkinase PF00069.25 EAX97796.1 - 1.3e-71 241.0 0.0 1.8e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97796.1 - 1.3e-41 142.6 0.0 1.8e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97796.1 - 1.1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX97796.1 - 0.004 16.2 0.9 0.0061 15.5 0.1 1.8 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EAX97796.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX97796.1 - 0.035 13.7 0.5 0.22 11.1 0.2 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EAX97796.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP_M PF14637.6 EAX97796.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain Pkinase_fungal PF17667.1 EAX97796.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EB1 PF03271.17 EAX97797.1 - 3.3e-06 27.2 0.5 3.3e-06 27.2 0.5 3.1 2 1 1 3 3 3 1 EB1-like C-terminal motif CH PF00307.31 EAX97797.1 - 0.0096 16.1 0.3 0.025 14.8 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF4795 PF16043.5 EAX97797.1 - 0.011 15.4 0.8 0.011 15.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Med9 PF07544.13 EAX97797.1 - 0.04 14.0 1.0 0.083 13.0 1.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin-6_N PF09177.11 EAX97797.1 - 0.041 14.4 0.3 0.068 13.7 0.3 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Not1 PF04054.15 EAX97798.1 - 6.7e-30 104.2 7.0 1.3e-29 103.3 3.6 2.9 2 2 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAX97798.1 - 3.4e-09 36.4 0.0 1.4e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain RPN7 PF10602.9 EAX97798.1 - 0.043 13.5 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF148 PF02520.17 EAX97798.1 - 7.9 6.6 7.9 0.74 10.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 Dpy19 PF10034.9 EAX97799.1 - 0.0013 17.0 7.5 0.0017 16.7 7.5 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation FAM176 PF14851.6 EAX97799.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 FAM176 family WBP-1 PF11669.8 EAX97799.1 - 0.11 13.1 2.2 0.38 11.4 0.1 2.4 1 1 1 2 2 2 0 WW domain-binding protein 1 OAD_gamma PF04277.13 EAX97799.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.1 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 EAX97799.1 - 2.2 9.2 5.4 7.3 7.5 0.0 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4131 PF13567.6 EAX97799.1 - 4.4 6.9 11.1 0.047 13.3 1.4 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) SR-25 PF10500.9 EAX97801.1 - 0.043 13.4 10.7 0.069 12.8 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 EAX97801.1 - 0.11 13.0 11.6 0.28 11.6 0.7 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX97802.1 - 2.9e-35 121.0 27.3 1.1e-19 70.7 7.4 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97802.1 - 1.2e-09 37.7 1.0 0.11 12.2 0.0 5.2 3 2 2 5 5 5 3 Leucine rich repeat Rax2 PF12768.7 EAX97802.1 - 0.0033 16.9 0.1 0.007 15.8 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 EAX97802.1 - 0.0041 16.5 3.3 0.0066 15.8 3.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 EAX97802.1 - 0.0052 16.7 0.6 0.0091 15.9 0.6 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.16 EAX97802.1 - 0.014 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pentapeptide_3 PF13576.6 EAX97802.1 - 0.024 14.8 13.4 0.24 11.6 1.2 4.2 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) TMEM154 PF15102.6 EAX97802.1 - 0.028 14.3 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Myc_target_1 PF15179.6 EAX97802.1 - 0.065 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Myc target protein 1 Stevor PF17410.2 EAX97802.1 - 0.23 11.0 2.8 0.39 10.2 2.8 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5385 PF17359.2 EAX97802.1 - 0.26 10.8 1.2 0.36 10.3 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Trypan_PARP PF05887.11 EAX97802.1 - 1.6 8.7 73.1 6.1e+03 -2.9 0.0 3.5 2 1 0 2 2 1 0 Procyclic acidic repetitive protein (PARP) RIFIN PF02009.16 EAX97802.1 - 2 8.2 6.4 3.6 7.4 6.4 1.3 1 0 0 1 1 1 0 Rifin ECSCR PF15820.5 EAX97802.1 - 4.5 7.2 6.9 1 9.2 2.6 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator LNS2 PF08235.13 EAX97803.1 - 2.4e-56 190.8 0.0 3.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EAX97803.1 - 3.6e-19 68.6 0.0 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.6 EAX97803.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DNase_II PF03265.15 EAX97805.1 - 1.2e-72 244.9 0.9 1.4e-72 244.8 0.9 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II TPT PF03151.16 EAX97806.1 - 8.8e-33 113.9 19.6 1.1e-32 113.6 19.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EAX97806.1 - 5.5e-11 42.2 24.3 2.2e-10 40.2 24.3 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EAX97806.1 - 5.9e-11 42.7 19.1 1.7e-06 28.2 3.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 EAX97806.1 - 0.0013 17.9 0.3 0.0013 17.9 0.3 2.7 2 1 0 2 2 2 1 Magnesium transporter NIPA Nuc_sug_transp PF04142.15 EAX97806.1 - 0.013 14.7 7.3 0.21 10.7 0.2 2.4 2 1 0 2 2 2 0 Nucleotide-sugar transporter SLC35F PF06027.12 EAX97806.1 - 0.059 12.9 13.0 0.7 9.3 1.5 2.5 1 1 0 2 2 2 0 Solute carrier family 35 TMEM234 PF10639.9 EAX97806.1 - 0.12 12.4 12.7 0.073 13.1 2.7 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 PUNUT PF16913.5 EAX97806.1 - 0.17 11.1 19.9 36 3.4 19.9 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF2070 PF09843.9 EAX97806.1 - 0.84 7.8 19.7 3.5 5.8 8.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Med9 PF07544.13 EAX97807.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RNaseH_C PF09293.10 EAX97807.1 - 0.033 14.5 0.2 0.12 12.7 0.1 1.8 1 1 1 2 2 2 0 T4 RNase H, C terminal KLRAQ PF10205.9 EAX97807.1 - 0.04 14.2 0.7 0.057 13.7 0.3 1.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein CtIP_N PF10482.9 EAX97807.1 - 0.046 13.8 0.5 0.059 13.4 0.5 1.1 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF3287 PF11690.8 EAX97807.1 - 0.07 12.9 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) WD40 PF00400.32 EAX97808.1 - 1.2e-14 54.5 0.5 9e-05 23.2 0.6 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX97808.1 - 3.9e-11 43.1 0.2 0.0034 17.7 0.0 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX97808.1 - 0.0072 15.3 0.1 0.27 10.2 0.1 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3979 PF13141.6 EAX97808.1 - 0.043 14.1 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) Cytochrom_D1 PF02239.16 EAX97808.1 - 0.056 12.0 0.0 0.18 10.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 EAX97808.1 - 0.067 12.5 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Folate_rec PF03024.14 EAX97808.1 - 0.16 11.8 1.8 9.6 6.0 0.7 2.2 2 0 0 2 2 2 0 Folate receptor family Glyco_hydro_77 PF02446.17 EAX97809.1 - 4.1e-149 497.4 5.6 5.2e-149 497.1 5.6 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAX97809.1 - 2.6e-42 142.6 0.2 5.4e-23 80.7 0.1 2.9 2 0 0 2 2 2 2 Starch binding domain DHHC PF01529.20 EAX97810.1 - 1.7e-20 73.4 2.7 1.7e-20 73.4 2.7 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sprouty PF05210.13 EAX97810.1 - 0.19 12.1 6.0 0.36 11.2 5.8 1.5 1 1 0 1 1 1 0 Sprouty protein (Spry) HemY_N PF07219.13 EAX97810.1 - 9.6 6.5 7.5 7.1 6.9 3.2 2.1 1 1 1 2 2 2 0 HemY protein N-terminus Phage_antitermQ PF06530.12 EAX97811.1 - 0.0071 16.3 0.6 0.039 13.8 0.6 2.3 1 0 0 1 1 1 1 Phage antitermination protein Q DUF3447 PF11929.8 EAX97812.1 - 1.2e-39 134.1 7.6 1.2e-39 134.1 7.6 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97812.1 - 1.2e-13 51.4 0.8 2.9e-08 34.2 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97812.1 - 6.7e-13 48.9 1.4 3.8e-06 27.3 0.0 4.2 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97812.1 - 1.5e-09 37.9 0.7 1.3e-07 31.7 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX97812.1 - 7e-09 35.2 4.6 1.6e-06 28.0 0.1 4.4 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX97812.1 - 3.1e-08 33.7 1.2 2.5e-07 30.9 0.1 2.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) TrbL PF04610.14 EAX97814.1 - 0.28 10.9 0.0 0.37 10.5 0.0 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein CAP PF00188.26 EAX97815.1 - 3.2e-05 24.8 0.3 0.18 12.6 0.0 3.7 3 1 0 3 3 3 2 Cysteine-rich secretory protein family BRCT_2 PF16589.5 EAX97815.1 - 0.069 13.6 0.2 7.7 7.0 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Kelch_4 PF13418.6 EAX97816.1 - 2e-29 101.4 6.2 1.4e-09 37.8 0.1 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX97816.1 - 1.8e-17 63.0 8.4 0.0012 19.0 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 EAX97816.1 - 1e-16 60.5 5.3 0.0051 16.8 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EAX97816.1 - 1.5e-14 53.8 4.9 0.00076 19.7 0.0 5.1 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX97816.1 - 9.4e-13 47.5 6.8 0.0016 18.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EAX97816.1 - 3e-09 36.5 9.1 0.24 11.4 0.1 4.7 5 0 0 5 5 5 4 Kelch motif DUF3447 PF11929.8 EAX97817.1 - 2.4e-25 88.3 3.3 2.4e-25 88.3 3.3 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97817.1 - 2.3e-19 69.8 2.8 2.7e-09 37.5 0.0 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97817.1 - 7.8e-14 50.4 3.8 3e-06 27.1 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EAX97817.1 - 8e-14 51.4 2.3 6.7e-07 29.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX97817.1 - 5.6e-12 45.6 0.9 2.7e-05 24.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX97817.1 - 2.6e-10 40.6 2.2 0.005 17.4 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) HBD PF18534.1 EAX97817.1 - 0.059 13.5 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Helical bundle domain DUF3258 PF11646.8 EAX97817.1 - 0.58 10.3 7.7 0.79 9.9 0.2 3.1 2 1 0 3 3 3 0 Protein of unknown function DUF3258 PTR PF12789.7 EAX97819.1 - 3.3e-16 59.1 2.5 3.3e-16 59.1 2.5 6.1 4 2 1 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX97819.1 - 0.071 12.9 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX97819.1 - 1.6 9.2 8.4 2.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF3839 PF12943.7 EAX97821.1 - 3.2e-79 265.8 11.6 4.2e-79 265.4 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX97821.1 - 0.069 12.7 0.4 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 SLOG cluster2 Pox_A32 PF04665.12 EAX97822.1 - 7.3e-07 28.9 2.6 7.3e-07 28.9 2.6 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX97822.1 - 3.9e-05 23.5 0.3 0.37 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX97822.1 - 4.3e-05 23.8 0.2 0.00032 21.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX97822.1 - 0.00049 20.1 4.9 0.00064 19.8 3.9 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97822.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97822.1 - 0.0031 17.4 0.6 0.0031 17.4 0.6 1.9 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 EAX97822.1 - 0.006 16.3 3.0 0.015 14.9 0.4 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97822.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX97822.1 - 0.091 12.3 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX97822.1 - 0.1 13.0 0.1 0.92 9.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAX97822.1 - 0.13 12.3 1.0 1.9 8.5 1.0 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF573 PF04504.14 EAX97822.1 - 0.57 10.9 13.4 0.14 12.8 2.3 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1827 PF08860.10 EAX97822.1 - 0.58 10.4 4.1 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) TGBp3 PF02495.17 EAX97823.1 - 0.031 13.9 1.5 0.053 13.2 1.5 1.4 1 0 0 1 1 1 0 Triple gene block 3 Pkinase PF00069.25 EAX97824.1 - 2.4e-36 125.5 0.1 3.5e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97824.1 - 1.2e-18 67.3 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Securin PF04856.13 EAX97824.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Aldo_ket_red PF00248.21 EAX97825.1 - 8.5e-44 149.9 0.0 1.9e-43 148.7 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4788 PF16032.5 EAX97825.1 - 0.22 10.5 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) DUF4411 PF14367.6 EAX97826.1 - 0.023 14.6 4.2 1.5 8.7 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF4116 PF13475.6 EAX97826.1 - 0.024 14.4 0.6 0.089 12.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF5377 PF17347.2 EAX97826.1 - 0.5 10.8 3.6 14 6.1 0.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5377) CUE PF02845.16 EAX97827.1 - 0.071 12.8 0.5 8.3 6.2 0.0 3.7 3 0 0 3 3 3 0 CUE domain RTP1_C1 PF10363.9 EAX97827.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.5 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 EAX97827.1 - 1.1 9.2 7.8 2.7 8.0 0.6 3.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain Sugar_tr PF00083.24 EAX97828.1 - 7.3e-48 163.5 27.3 5.3e-32 111.3 17.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX97828.1 - 2.4e-17 62.9 18.0 2.4e-17 62.9 18.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EAX97828.1 - 0.0021 17.0 10.0 0.0038 16.1 10.0 1.4 1 0 0 1 1 1 1 MFS_1 like family THEG4 PF15834.5 EAX97828.1 - 0.057 13.4 0.2 0.086 12.8 0.2 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 Mem_trans PF03547.18 EAX97829.1 - 2.7e-19 68.8 0.3 3.6e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 Membrane transport protein SLC12 PF03522.15 EAX97829.1 - 0.22 10.5 3.7 0.3 10.0 3.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIF_alpha PF05793.12 EAX97829.1 - 4.6 5.7 27.4 5.8 5.4 27.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Oxidored_FMN PF00724.20 EAX97831.1 - 6.2e-61 206.6 0.0 7.2e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 EAX97831.1 - 0.00016 21.2 0.0 0.00041 19.9 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 EAX97831.1 - 0.0002 20.5 0.1 0.00074 18.6 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase AP_endonuc_2 PF01261.24 EAX97831.1 - 0.0083 15.6 0.0 0.28 10.6 0.0 2.1 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel IMPDH PF00478.25 EAX97831.1 - 0.017 14.1 0.0 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Fer4 PF00037.27 EAX97831.1 - 0.26 11.1 2.3 0.76 9.7 2.3 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain DSHCT PF08148.12 EAX97832.1 - 5.5e-38 130.2 0.0 2.5e-37 128.1 0.0 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EAX97832.1 - 2.9e-22 79.9 5.9 5.6e-22 78.9 5.9 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EAX97832.1 - 1.8e-17 63.7 0.0 5.6e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAX97832.1 - 2.3e-07 31.2 0.1 1.3e-06 28.7 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 EAX97832.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 EAX97832.1 - 0.02 14.0 0.0 0.053 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein FlxA PF14282.6 EAX97832.1 - 0.48 10.5 5.7 0.94 9.5 3.6 2.4 2 0 0 2 2 2 0 FlxA-like protein CCDC-167 PF15188.6 EAX97832.1 - 1.2 9.5 11.3 1.3 9.4 4.7 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GIT_CC PF16559.5 EAX97832.1 - 3.2 7.7 5.3 7.3 6.5 3.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MRP-S26 PF14943.6 EAX97832.1 - 3.4 7.6 10.4 21 5.0 0.0 3.5 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S26 THOC7 PF05615.13 EAX97832.1 - 3.8 7.8 9.0 1.1 9.6 2.3 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 EzrA PF06160.12 EAX97832.1 - 7.3 4.6 14.0 4.7 5.3 4.3 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Gly_rich PF12810.7 EAX97833.1 - 7.9e-26 91.4 38.6 1e-25 91.1 38.6 1.0 1 0 0 1 1 1 1 Glycine rich protein NLPC_P60 PF00877.19 EAX97834.1 - 1.6e-13 50.6 0.1 2.2e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 EAX97834.1 - 0.09 12.7 2.0 0.71 9.8 2.0 2.1 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Pkinase PF00069.25 EAX97835.1 - 1.3e-56 191.9 0.2 1.3e-56 191.9 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97835.1 - 9.7e-39 133.2 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX97835.1 - 1.1e-08 34.8 0.0 7.4e-08 32.1 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX97835.1 - 0.12 11.7 0.3 0.21 10.9 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX97835.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 EAX97837.1 - 9.5e-05 22.9 0.0 0.00011 22.8 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97837.1 - 0.00052 20.5 0.0 0.00057 20.4 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97837.1 - 0.0041 17.4 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_1 PF00515.28 EAX97838.1 - 1.6e-06 27.6 5.7 0.031 14.1 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX97838.1 - 9.2e-06 25.4 4.8 0.053 13.7 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAX97838.1 - 1e-05 25.4 0.8 0.22 11.8 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX97838.1 - 0.012 16.2 4.0 0.028 15.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX97838.1 - 0.014 15.7 1.9 0.85 10.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAX97838.1 - 0.072 14.0 2.9 0.16 12.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1958 PF09211.10 EAX97838.1 - 0.12 12.8 0.1 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) Ank_4 PF13637.6 EAX97839.1 - 6.5e-08 33.0 1.6 3.1e-06 27.6 1.6 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX97839.1 - 0.00017 21.9 2.7 0.0014 19.0 1.2 2.5 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EAX97839.1 - 0.0011 19.3 0.4 0.26 12.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EAX97839.1 - 0.0012 19.4 2.1 0.012 16.2 1.8 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97839.1 - 0.012 15.9 1.6 0.095 13.1 0.1 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) EPTP PF03736.17 EAX97840.1 - 0.14 12.2 1.0 0.36 10.9 0.0 2.2 3 0 0 3 3 3 0 EPTP domain Tmemb_9 PF05434.11 EAX97841.1 - 4.3e-06 26.7 1.5 4.3e-06 26.7 1.5 2.5 2 1 0 2 2 1 1 TMEM9 TMEM154 PF15102.6 EAX97841.1 - 3.2e-05 23.8 6.3 3.2e-05 23.8 6.3 3.9 2 1 1 4 4 3 1 TMEM154 protein family FAM176 PF14851.6 EAX97841.1 - 0.00015 21.4 2.6 0.00015 21.4 2.6 2.5 1 1 1 2 2 2 1 FAM176 family V_ATPase_I PF01496.19 EAX97841.1 - 0.00069 17.7 6.0 0.00069 17.7 6.0 2.1 1 1 1 2 2 1 1 V-type ATPase 116kDa subunit family RIFIN PF02009.16 EAX97841.1 - 0.0014 18.6 1.5 0.0014 18.6 1.5 2.7 1 1 1 2 2 1 1 Rifin Stevor PF17410.2 EAX97841.1 - 0.0026 17.4 6.5 0.0026 17.4 6.5 3.0 2 1 1 3 3 2 1 Subtelomeric Variable Open Reading frame Pox_A21 PF05323.12 EAX97841.1 - 0.0028 18.2 0.1 0.015 15.9 0.0 2.3 2 0 0 2 2 1 1 Poxvirus A21 Protein YajC PF02699.15 EAX97841.1 - 0.0043 16.9 2.2 0.011 15.7 2.2 1.7 1 0 0 1 1 1 1 Preprotein translocase subunit O-antigen_lig PF13425.6 EAX97841.1 - 0.006 15.4 10.2 0.006 15.4 10.2 1.8 1 1 1 2 2 2 1 O-antigen ligase like membrane protein PIRT PF15099.6 EAX97841.1 - 0.0069 16.0 0.1 0.0069 16.0 0.1 2.6 3 0 0 3 3 1 1 Phosphoinositide-interacting protein family CLN3 PF02487.17 EAX97841.1 - 0.007 15.5 4.6 0.007 15.5 4.6 2.3 1 1 1 2 2 1 1 CLN3 protein Phage_Gp23 PF10669.9 EAX97841.1 - 0.0081 16.5 8.4 0.0081 16.5 8.4 2.2 2 0 0 2 2 1 1 Protein gp23 (Bacteriophage A118) TMIE PF16038.5 EAX97841.1 - 0.0087 15.9 2.4 0.026 14.4 2.4 1.8 1 0 0 1 1 1 1 TMIE protein Vpu PF00558.19 EAX97841.1 - 0.013 15.2 6.6 0.036 13.8 6.6 1.7 1 0 0 1 1 1 0 Vpu protein MscL PF01741.18 EAX97841.1 - 0.013 15.7 0.5 0.048 14.0 0.5 2.0 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL FHIPEP PF00771.20 EAX97841.1 - 0.015 13.8 0.1 0.02 13.4 0.1 1.3 1 0 0 1 1 1 0 FHIPEP family DUF5436 PF17504.2 EAX97841.1 - 0.017 15.5 0.5 0.043 14.1 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5436) DUF4692 PF15763.5 EAX97841.1 - 0.032 14.7 1.3 0.032 14.7 1.3 3.5 2 1 1 3 3 2 0 Regulator of human erythroid cell expansion (RHEX) DUF4446 PF14584.6 EAX97841.1 - 0.032 14.2 4.4 0.091 12.7 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) IgaA PF07095.11 EAX97841.1 - 0.033 12.2 1.0 0.047 11.7 1.0 1.2 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Orf78 PF06024.12 EAX97841.1 - 0.044 14.1 0.7 0.044 14.1 0.7 3.7 1 1 1 2 2 1 0 Orf78 (ac78) DUF1772 PF08592.11 EAX97841.1 - 0.045 14.1 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) tRNA_anti-like PF12869.7 EAX97841.1 - 0.051 13.2 1.9 0.14 11.7 0.5 2.4 1 1 1 2 2 1 0 tRNA_anti-like LapA_dom PF06305.11 EAX97841.1 - 0.058 13.2 2.7 0.14 12.0 2.7 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Defensin_5 PF18251.1 EAX97841.1 - 0.059 13.5 0.8 0.059 13.5 0.8 2.2 2 0 0 2 2 1 0 Fungal defensin Copsin DUF3328 PF11807.8 EAX97841.1 - 0.067 13.0 3.2 0.052 13.3 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF2615 PF11027.8 EAX97841.1 - 0.068 13.3 0.0 0.068 13.3 0.0 3.3 2 1 1 3 3 2 0 Protein of unknown function (DUF2615) DUF2500 PF10694.9 EAX97841.1 - 0.097 13.2 0.4 0.097 13.2 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) Ly49 PF08391.10 EAX97841.1 - 0.097 13.0 8.2 0.18 12.2 7.3 1.8 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Baculo_11_kDa PF06143.11 EAX97841.1 - 0.12 12.0 0.3 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4381 PF14316.6 EAX97841.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 EAX97841.1 - 0.14 13.0 5.5 0.89 10.5 5.1 2.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Connexin PF00029.19 EAX97841.1 - 0.25 11.1 20.9 15 5.2 20.9 2.5 1 1 0 1 1 1 0 Connexin Ycf70 PF17382.2 EAX97841.1 - 0.3 11.5 1.9 0.71 10.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Peptidase_M56 PF05569.11 EAX97841.1 - 0.33 10.1 3.3 0.2 10.8 1.1 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF4834 PF16118.5 EAX97841.1 - 0.38 11.7 24.5 93 4.1 24.5 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2448 PF10476.9 EAX97841.1 - 0.51 10.2 4.0 1.9 8.3 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DC_STAMP PF07782.13 EAX97841.1 - 0.83 9.4 4.0 2.2 8.1 4.0 1.9 1 1 0 1 1 1 0 DC-STAMP-like protein 60KD_IMP PF02096.20 EAX97841.1 - 0.9 9.4 5.4 2 8.3 5.4 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein GRP PF07172.11 EAX97841.1 - 1.2 9.9 5.9 1.2 9.9 0.7 2.7 1 1 1 2 2 2 0 Glycine rich protein family SpoIIIAH PF12685.7 EAX97841.1 - 1.4 8.7 28.1 0.015 15.1 9.0 2.3 1 1 1 2 2 1 0 SpoIIIAH-like protein CBP_BcsG PF11658.8 EAX97841.1 - 1.8 6.9 5.8 0.98 7.7 2.5 2.0 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsG S1FA PF04689.13 EAX97841.1 - 2.4 8.4 7.2 0.19 11.9 2.0 1.8 2 0 0 2 2 1 0 DNA binding protein S1FA Ctr PF04145.15 EAX97841.1 - 2.6 8.6 16.8 1.6e+02 2.8 16.8 2.8 1 1 0 1 1 1 0 Ctr copper transporter family OSTbeta PF15048.6 EAX97841.1 - 2.8 8.1 14.5 0.038 14.1 2.6 2.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein TMEMspv1-c74-12 PF11044.8 EAX97841.1 - 4.3 7.4 22.1 0.067 13.2 14.4 2.1 2 0 0 2 2 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein YMF19 PF02326.15 EAX97841.1 - 4.5 8.1 6.8 9.5 7.1 4.8 2.7 1 1 1 2 2 1 0 Plant ATP synthase F0 DUF2140 PF09911.9 EAX97841.1 - 4.9 6.7 9.3 0.42 10.1 3.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Neur_chan_memb PF02932.16 EAX97841.1 - 6.3 6.8 17.7 34 4.4 17.7 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cellulose_synt PF03552.14 EAX97841.1 - 7.5 4.9 9.1 14 4.0 9.1 1.5 1 0 0 1 1 1 0 Cellulose synthase Aa_trans PF01490.18 EAX97842.1 - 3.2e-25 88.7 38.6 3.7e-25 88.5 38.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.7 EAX97843.1 - 1.8e-82 272.0 35.8 4.4e-19 68.9 0.4 7.7 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97843.1 - 2.9e-70 229.8 13.9 2.5e-08 34.0 0.1 12.2 11 1 1 12 12 12 10 Ankyrin repeat Ank_4 PF13637.6 EAX97843.1 - 1.9e-67 222.8 11.3 7e-09 36.1 0.0 11.1 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97843.1 - 1.5e-61 197.0 8.9 5.5e-06 26.3 0.0 12.8 12 1 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EAX97843.1 - 4.9e-55 182.9 4.9 2.1e-11 43.8 0.0 9.2 2 1 4 9 9 9 9 Ankyrin repeats (many copies) Mic1 PF07035.12 EAX97843.1 - 0.0034 17.1 1.3 3.5 7.3 0.0 4.2 3 2 0 3 3 3 1 Colon cancer-associated protein Mic1-like GATase_7 PF13537.6 EAX97843.1 - 0.0052 16.7 0.0 38 4.2 0.0 4.3 4 0 0 4 4 4 0 Glutamine amidotransferase domain MetallophosN PF16371.5 EAX97843.1 - 0.057 13.7 0.2 11 6.4 0.0 3.2 2 1 1 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Ubiquitin_2 PF14560.6 EAX97843.1 - 0.068 13.6 0.5 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4108 PF13390.6 EAX97845.1 - 1.2e-57 193.9 4.7 1.3e-57 193.7 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX97847.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX97847.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX97847.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX97847.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX97847.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX97847.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX97847.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX97847.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX97847.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX97847.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX97847.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX97847.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3447 PF11929.8 EAX97848.1 - 8.7e-35 118.5 19.5 2.4e-34 117.1 8.9 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97848.1 - 7.9e-21 74.4 1.2 1.5e-16 60.8 0.3 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97848.1 - 7.9e-13 48.2 0.3 2.4e-06 27.7 0.1 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAX97848.1 - 2.7e-11 43.8 3.6 9.7e-07 29.2 0.1 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97848.1 - 3.8e-11 42.2 9.1 2.6e-05 24.3 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAX97848.1 - 5.8e-10 39.2 2.8 2.7e-06 27.6 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) UCH PF00443.29 EAX97849.1 - 3.4e-56 190.6 0.0 7.8e-56 189.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX97849.1 - 1.1e-18 67.6 0.5 9e-18 64.7 0.1 2.6 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 EAX97849.1 - 1.3e-10 41.4 1.0 1.9e-05 24.4 0.1 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RA PF00788.23 EAX97849.1 - 0.059 14.0 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PhnA_Zn_Ribbon PF08274.12 EAX97849.1 - 2.3 8.2 6.5 0.83 9.7 1.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-MIZ PF02891.20 EAX97849.1 - 8.5 6.2 6.9 0.72 9.6 1.5 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger BRE1 PF08647.11 EAX97850.1 - 0.067 13.3 1.7 0.38 10.8 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase 14-3-3 PF00244.20 EAX97851.1 - 5.2e-47 160.2 6.0 5.9e-47 160.0 6.0 1.0 1 0 0 1 1 1 1 14-3-3 protein NAC PF01849.18 EAX97852.1 - 5.8e-08 32.6 0.0 2e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 NAC domain HSBP1 PF06825.12 EAX97853.1 - 5.3e-05 23.0 1.1 6.6e-05 22.7 1.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 TPR_MLP1_2 PF07926.12 EAX97853.1 - 0.0013 18.8 2.1 0.0015 18.6 2.1 1.0 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein UPF0184 PF03670.13 EAX97853.1 - 0.0017 18.7 0.5 0.0022 18.4 0.5 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) Nsp1_C PF05064.13 EAX97853.1 - 0.059 13.2 2.1 0.067 13.0 2.1 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region Fun_ATP-synt_8 PF05933.13 EAX97854.1 - 0.063 13.5 1.5 0.063 13.5 1.5 2.1 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) GPS2_interact PF15784.5 EAX97856.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97856.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAX97857.1 - 0.034 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX97858.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX97858.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX97859.1 - 0.026 14.6 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX97860.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX97860.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX97861.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97861.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DNA_pol_B_2 PF03175.13 EAX97864.1 - 8e-23 81.0 9.0 2.2e-22 79.6 9.0 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX97866.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAX97866.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Trypan_PARP PF05887.11 EAX97867.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX97867.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Inhibitor_I69 PF13734.6 EAX97869.1 - 0.03 14.7 0.1 0.057 13.8 0.1 1.5 1 0 0 1 1 1 0 Spi protease inhibitor Tox-URI2 PF15653.6 EAX97869.1 - 0.084 13.1 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 URI fold toxin 2 DUF2207 PF09972.9 EAX97870.1 - 0.076 11.8 3.6 0.38 9.5 1.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Vpu PF00558.19 EAX97870.1 - 0.11 12.3 12.3 2 8.3 0.2 3.4 3 0 0 3 3 3 0 Vpu protein Cyt_bd_oxida_I PF01654.17 EAX97870.1 - 0.73 8.4 5.3 0.3 9.7 1.9 1.9 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit I DUF202 PF02656.15 EAX97870.1 - 0.8 10.2 2.6 0.97 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) RIFIN PF02009.16 EAX97870.1 - 1.6 8.5 9.3 0.41 10.5 3.6 2.3 2 0 0 2 2 2 0 Rifin Orf78 PF06024.12 EAX97870.1 - 2 8.7 9.7 0.91 9.9 1.1 3.3 3 0 0 3 3 3 0 Orf78 (ac78) DUF1282 PF06930.12 EAX97870.1 - 2.6 7.8 9.8 0.98 9.2 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) Pex24p PF06398.11 EAX97870.1 - 3.1 6.7 12.4 0.22 10.5 3.6 2.4 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF5345 PF17280.2 EAX97870.1 - 4.3 7.4 7.4 1.3 9.0 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Guanylate_cyc PF00211.20 EAX97871.1 - 8.5e-15 54.8 0.2 9.8e-15 54.6 0.2 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GGDEF PF00990.21 EAX97871.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Ank_2 PF12796.7 EAX97873.1 - 1.6e-36 124.7 4.8 2.6e-16 60.0 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97873.1 - 7.2e-29 99.8 2.1 6.3e-07 29.8 0.0 4.7 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97873.1 - 1.8e-21 75.9 0.3 4.2e-05 23.7 0.0 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97873.1 - 1.7e-20 70.9 0.0 0.0079 16.6 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX97873.1 - 8.1e-18 64.0 0.1 0.0037 17.6 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat ZapB PF06005.12 EAX97873.1 - 0.02 15.3 1.7 0.047 14.1 1.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EAX97873.1 - 0.042 13.8 1.6 0.077 12.9 1.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain YabA PF06156.13 EAX97873.1 - 0.2 12.3 5.4 0.12 13.0 1.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 EAX97873.1 - 2.6 8.2 7.3 0.36 11.0 2.4 2.1 2 0 0 2 2 2 0 bZIP transcription factor PI3_PI4_kinase PF00454.27 EAX97874.1 - 5.7e-44 150.8 0.0 1.6e-43 149.4 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EAX97874.1 - 9.7e-17 61.2 0.1 8.7e-16 58.2 0.0 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EAX97874.1 - 2.6e-10 39.9 0.3 8.6e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 FATC domain PknG_TPR PF16918.5 EAX97874.1 - 0.063 12.0 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Cnd1 PF12717.7 EAX97874.1 - 0.063 13.3 6.3 1.7 8.7 0.0 4.5 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3150 PF11348.8 EAX97874.1 - 0.13 11.5 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF3385 PF11865.8 EAX97874.1 - 3.3 7.6 16.8 4.5 7.2 0.2 5.9 3 1 2 6 6 6 0 Domain of unknown function (DUF3385) Ank_2 PF12796.7 EAX97876.1 - 1.1e-19 70.8 0.8 3.8e-11 43.4 0.0 3.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97876.1 - 8.4e-11 42.2 0.0 7.5e-07 29.6 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97876.1 - 1.4e-07 31.7 0.0 0.015 15.6 0.0 4.9 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97876.1 - 4.4e-06 26.6 0.0 20 6.1 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 EAX97876.1 - 3.7e-05 23.6 0.6 3.7e-05 23.6 0.6 3.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX97876.1 - 0.0027 18.1 0.0 91 3.8 0.0 5.0 4 1 0 4 4 4 0 Ankyrin repeat AbiJ_NTD4 PF18863.1 EAX97876.1 - 0.006 17.1 3.1 0.14 12.6 0.3 2.3 2 0 0 2 2 2 1 AbiJ N-terminal domain 4 ASH PF15780.5 EAX97877.1 - 1e-23 83.4 16.8 0.00027 21.1 1.0 6.8 6 0 0 6 6 6 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EAX97877.1 - 3.8e-11 42.9 14.8 0.00035 20.5 0.1 6.7 6 1 0 6 6 6 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EAX97877.1 - 1.3e-09 38.1 15.8 0.0019 18.4 1.2 6.3 7 1 0 7 7 7 4 Transmembrane protein 131-like MYCBPAP PF14646.6 EAX97877.1 - 6.6e-05 22.0 0.1 0.072 12.0 0.0 2.8 3 0 0 3 3 3 2 MYCBP-associated protein family PapD-like PF14874.6 EAX97877.1 - 0.009 16.1 0.1 0.54 10.4 0.0 3.9 4 0 0 4 4 4 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EAX97877.1 - 0.41 10.5 0.0 0.41 10.5 0.0 5.9 6 1 1 7 7 7 0 MSP (Major sperm protein) domain Ank_2 PF12796.7 EAX97878.1 - 1.1e-45 154.1 4.0 6e-16 58.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97878.1 - 1.3e-32 111.7 0.6 2.8e-07 31.0 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97878.1 - 1e-22 79.9 0.2 1.8e-05 24.9 0.0 5.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97878.1 - 1.1e-20 71.4 0.0 0.0038 17.6 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAX97878.1 - 1.5e-20 72.6 0.0 0.0011 19.3 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ail_Lom PF06316.11 EAX97878.1 - 0.0072 16.1 0.1 2.9 7.6 0.0 2.2 2 0 0 2 2 2 2 Enterobacterial Ail/Lom protein Peptidase_M18 PF02127.15 EAX97879.1 - 3.9e-79 266.5 0.0 3.2e-78 263.4 0.0 1.9 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAX97879.1 - 2.1e-09 36.8 0.0 9.9e-09 34.6 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EAX97879.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 LZ3wCH PF18517.1 EAX97879.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Guanylate_cyc PF00211.20 EAX97880.1 - 3.2e-42 144.2 1.7 6e-42 143.3 0.2 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX97880.1 - 1.1e-09 38.5 1.4 4.2e-09 36.6 1.4 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX97880.1 - 0.00013 21.9 0.1 0.00034 20.6 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX97880.1 - 0.00067 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAX97880.1 - 0.004 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain Propep_M14 PF02244.16 EAX97880.1 - 0.044 14.2 0.3 0.28 11.6 0.1 2.4 2 0 0 2 2 2 0 Carboxypeptidase activation peptide V-set_2 PF15910.5 EAX97880.1 - 2.4 8.3 8.2 1.6 8.8 0.4 3.2 2 1 1 3 3 3 0 ICOS V-set domain Sugar_tr PF00083.24 EAX97881.1 - 8.4e-51 173.2 32.1 1.8e-33 116.1 12.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX97881.1 - 1.4e-21 76.8 24.8 5.1e-13 48.7 1.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX97881.1 - 1.9e-06 26.7 26.2 0.00029 19.5 4.9 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein SPC25 PF06703.11 EAX97881.1 - 7.6 6.3 9.1 9.1 6.0 2.3 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Stk19 PF10494.9 EAX97882.1 - 4.3e-11 43.0 0.0 6.5e-11 42.4 0.0 1.3 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 TIG PF01833.24 EAX97883.1 - 0.012 15.7 0.7 0.028 14.5 0.7 1.8 1 1 0 1 1 1 0 IPT/TIG domain SMN PF06003.12 EAX97883.1 - 0.023 13.9 0.1 0.031 13.5 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PQ-loop PF04193.14 EAX97884.1 - 5.2e-19 67.8 19.0 1.2e-15 57.0 4.4 3.2 2 1 1 3 3 3 2 PQ loop repeat ASC PF00858.24 EAX97884.1 - 4.9 6.0 7.4 9 5.1 3.6 2.2 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel PAP_assoc PF03828.19 EAX97885.1 - 5e-12 45.8 0.1 2e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAX97885.1 - 8.6e-11 42.0 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAX97885.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Methyltransf_16 PF10294.9 EAX97886.1 - 5.4e-20 71.8 0.0 7.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EAX97886.1 - 1.2e-08 35.0 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX97886.1 - 7.2e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAX97886.1 - 4.6e-07 29.5 0.0 6.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EAX97886.1 - 6.2e-07 30.0 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX97886.1 - 1.5e-06 28.8 0.0 2.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX97886.1 - 0.00013 22.6 0.0 0.00029 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAX97886.1 - 0.00021 20.8 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EAX97886.1 - 0.0003 20.4 0.0 0.00039 20.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EAX97886.1 - 0.0022 17.7 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GidB PF02527.15 EAX97886.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G NodS PF05401.11 EAX97886.1 - 0.17 11.5 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Rho_GDI PF02115.17 EAX97887.1 - 7.9e-22 78.0 0.2 9.1e-22 77.8 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Tap-RNA_bind PF09162.10 EAX97887.1 - 0.048 13.5 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Tap, RNA-binding LRR_5 PF13306.6 EAX97888.1 - 3.7e-98 324.3 118.9 1.1e-20 73.9 9.2 8.4 2 1 7 9 9 9 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97888.1 - 3.9e-24 84.2 1.8 0.12 12.1 0.0 15.4 4 3 15 21 21 21 13 Leucine rich repeat LRR_4 PF12799.7 EAX97888.1 - 4e-07 30.3 15.9 8.9 6.9 1.5 10.8 7 4 1 8 8 8 2 Leucine Rich repeats (2 copies) DTC PF18102.1 EAX97888.1 - 0.014 15.5 0.7 79 3.4 0.0 4.1 4 0 0 4 4 4 0 Deltex C-terminal domain Myb_DNA-binding PF00249.31 EAX97889.1 - 1.1e-35 121.6 3.7 7.7e-17 61.2 0.2 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX97889.1 - 1.3e-31 108.6 2.1 1.9e-18 66.5 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX97889.1 - 1.4e-08 34.7 0.3 0.0016 18.5 0.2 2.7 2 1 0 2 2 2 2 SLIDE Rap1_C PF11626.8 EAX97889.1 - 0.0055 16.8 0.1 2.4 8.3 0.0 2.5 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 EAX97889.1 - 0.022 15.1 4.4 0.38 11.1 0.2 2.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 EAX97889.1 - 0.099 12.5 2.7 0.4 10.6 0.0 2.7 3 0 0 3 3 3 0 Myb DNA-binding like NapB PF03892.14 EAX97890.1 - 0.043 13.8 1.7 1.1 9.3 1.7 2.4 1 1 1 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Effector_1 PF04518.12 EAX97890.1 - 1.4 8.0 6.9 0.28 10.3 1.1 2.2 2 1 0 2 2 2 0 Effector from type III secretion system Cauli_AT PF03233.13 EAX97890.1 - 1.5 8.7 6.5 5.5 6.9 4.8 2.5 1 1 0 1 1 1 0 Aphid transmission protein DUF4200 PF13863.6 EAX97891.1 - 3.1e-10 40.5 16.8 3.1e-10 40.5 16.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) DHHC PF01529.20 EAX97892.1 - 3.1e-22 79.1 2.3 3.1e-22 79.1 2.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SHIPPO-rpt PF07004.12 EAX97893.1 - 0.00082 20.2 12.2 0.2 12.6 0.6 3.8 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat BLOC1_2 PF10046.9 EAX97894.1 - 0.052 13.9 6.8 0.18 12.1 1.4 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mei5_like PF17021.5 EAX97894.1 - 0.081 13.0 5.7 0.062 13.3 4.0 1.5 1 1 1 2 2 2 0 Putative double-strand recombination repair-like UPF0449 PF15136.6 EAX97894.1 - 0.28 11.7 5.5 0.9 10.0 5.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4407 PF14362.6 EAX97895.1 - 0.65 9.3 10.9 0.82 9.0 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EAX97895.1 - 1.4 9.2 24.4 0.82 10.0 20.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PIN_8 PF18476.1 EAX97895.1 - 2.5 7.9 19.8 0.54 10.1 15.1 1.9 1 1 1 2 2 2 0 PIN like domain Epimerase PF01370.21 EAX97896.1 - 0.0032 17.0 0.0 0.042 13.3 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAX97896.1 - 0.0034 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GAS PF13851.6 EAX97897.1 - 0.00017 21.0 9.6 0.00017 21.0 9.6 6.1 3 2 3 6 6 6 4 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 EAX97897.1 - 0.00018 21.5 62.1 0.0097 16.0 1.0 8.8 5 3 3 8 8 8 4 bZIP transcription factor DUF1192 PF06698.11 EAX97897.1 - 0.059 13.4 7.9 5.7 7.1 0.5 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) YabA PF06156.13 EAX97897.1 - 0.078 13.6 64.9 0.36 11.5 3.5 7.3 3 2 4 7 7 7 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EAX97897.1 - 0.11 12.5 73.0 0.45 10.6 19.9 5.6 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EAX97897.1 - 0.64 8.8 78.0 0.42 9.4 9.2 4.7 3 2 2 5 5 5 0 Spc7 kinetochore protein ERM PF00769.19 EAX97897.1 - 7.6 6.3 64.3 1.1 9.0 16.5 3.5 2 2 1 4 4 4 0 Ezrin/radixin/moesin family Ank_2 PF12796.7 EAX97899.1 - 3.8e-81 267.7 37.1 8e-18 64.8 1.5 8.9 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97899.1 - 1.1e-75 247.0 16.6 6.4e-06 26.4 0.1 12.7 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.6 EAX97899.1 - 1.4e-74 245.5 23.9 5.6e-10 39.6 0.2 13.7 3 2 11 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97899.1 - 2.2e-61 196.6 16.9 0.00066 19.9 0.0 14.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 EAX97899.1 - 1.5e-58 194.1 12.0 1e-09 38.4 0.2 9.8 7 2 4 11 11 11 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97899.1 - 1.1e-36 124.6 5.6 1.1e-36 124.6 5.6 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Stap_Strp_toxin PF01123.20 EAX97899.1 - 5.7e-05 23.9 6.2 8.9 7.2 0.0 5.8 4 1 1 5 5 5 1 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3126 PF11324.8 EAX97899.1 - 0.0077 16.0 0.4 7.4 6.5 0.0 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF3126) RRM_5 PF13893.6 EAX97899.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3718 PF12514.8 EAX97899.1 - 0.18 12.0 23.2 21 5.3 0.1 8.7 9 1 1 10 10 10 0 Protein of unknown function (DUF3718) Ribosomal_L3 PF00297.22 EAX97900.1 - 6.3e-141 469.6 10.7 1.9e-139 464.8 10.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 FAM184 PF15665.5 EAX97901.1 - 0.005 16.7 27.6 0.005 16.7 27.6 7.4 1 1 6 7 7 7 3 Family with sequence similarity 184, A and B Phosphodiest PF01663.22 EAX97901.1 - 0.73 9.3 3.6 0.52 9.8 0.7 2.5 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase zf-C3HC4_2 PF13923.6 EAX97902.1 - 1.8e-11 43.6 13.7 1.8e-11 43.6 13.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX97902.1 - 6.3e-10 39.2 14.9 6.3e-10 39.2 14.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAX97902.1 - 1.3e-09 37.8 13.6 1.3e-09 37.8 13.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAX97902.1 - 1.3e-09 37.9 13.2 1.3e-09 37.9 13.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAX97902.1 - 3.6e-09 36.3 10.4 3.6e-09 36.3 10.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAX97902.1 - 6.6e-08 32.6 13.5 6.6e-08 32.6 13.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 EAX97902.1 - 1.4e-07 31.2 1.4 1.8e-07 30.8 1.4 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EAX97902.1 - 1.5e-06 28.1 11.4 1.5e-06 28.1 11.4 1.6 2 0 0 2 2 1 1 zinc-RING finger domain U-box PF04564.15 EAX97902.1 - 2.7e-06 27.5 0.1 5.7e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EAX97902.1 - 4e-05 23.4 13.1 4e-05 23.4 13.1 2.4 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAX97902.1 - 7.2e-05 23.0 12.2 0.00021 21.5 12.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EAX97902.1 - 0.00018 21.3 4.9 0.00036 20.4 4.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 EAX97902.1 - 0.00075 19.3 7.8 0.0015 18.3 7.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TackOD1 PF18551.1 EAX97902.1 - 0.0019 17.9 1.6 0.0019 17.9 1.6 1.9 1 1 0 2 2 2 1 Thaumarchaeal output domain 1 zf-RING_4 PF14570.6 EAX97902.1 - 0.083 12.7 11.2 0.37 10.6 11.2 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EAX97902.1 - 0.2 11.7 7.8 0.58 10.2 7.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-NOSIP PF15906.5 EAX97902.1 - 0.21 11.7 0.9 0.41 10.8 0.2 1.8 1 1 1 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_10 PF16685.5 EAX97902.1 - 0.27 11.4 10.5 0.053 13.7 6.7 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-P11 PF03854.14 EAX97902.1 - 1.1 9.0 10.0 5.5 6.7 10.0 2.0 1 1 0 1 1 1 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 EAX97902.1 - 1.3 9.1 8.4 2.5 8.2 8.4 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_11 PF17123.5 EAX97902.1 - 3.3 7.5 13.4 0.093 12.5 6.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF4366 PF14283.6 EAX97904.1 - 0.0018 18.3 0.5 0.0032 17.5 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) SKG6 PF08693.10 EAX97904.1 - 0.038 13.4 2.4 0.078 12.4 2.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 EAX97904.1 - 0.055 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SPATA6 PF14909.6 EAX97904.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Syndecan PF01034.20 EAX97904.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.1 1 0 0 1 1 1 0 Syndecan domain DUF2273 PF10031.9 EAX97904.1 - 0.11 12.5 1.2 0.33 11.0 1.2 1.8 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF1400 PF07176.11 EAX97906.1 - 0.00013 22.3 8.7 2.7 8.3 0.6 5.2 4 1 1 5 5 5 3 Alpha/beta hydrolase of unknown function (DUF1400) Vac14_Fab1_bd PF12755.7 EAX97906.1 - 0.046 14.3 1.4 7.4 7.2 0.0 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region LRR_5 PF13306.6 EAX97907.1 - 7.3e-88 291.1 91.9 7.7e-27 93.8 9.1 6.4 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX97907.1 - 1.6e-15 56.6 19.8 0.0053 16.5 0.9 8.6 5 2 3 8 8 8 6 Leucine rich repeat Microcin PF03526.13 EAX97907.1 - 0.0084 15.9 0.6 16 5.4 0.0 3.9 3 0 0 3 3 3 2 Colicin E1 (microcin) immunity protein LRR_4 PF12799.7 EAX97907.1 - 0.027 14.9 0.6 0.027 14.9 0.6 8.4 7 3 1 8 8 8 0 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 EAX97908.1 - 5.1e-12 46.2 10.5 5.1e-12 46.2 10.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) RasGAP PF00616.19 EAX97910.1 - 1e-09 38.4 9.6 3e-08 33.6 1.1 4.3 4 1 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EAX97910.1 - 4.3e-05 23.7 0.2 0.00086 19.5 0.1 3.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Pkinase PF00069.25 EAX97911.1 - 0.00057 19.3 0.1 0.00068 19.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain SGTA_dimer PF16546.5 EAX97911.1 - 0.12 12.2 0.2 0.44 10.4 0.0 2.0 3 0 0 3 3 3 0 Homodimerisation domain of SGTA PapD_N PF00345.20 EAX97913.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX97913.1 - 0.05 13.6 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAX97913.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX97914.1 - 0.02 15.3 0.7 0.026 14.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX97914.1 - 1.7 7.6 4.1 1.9 7.5 4.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX97914.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain TERB2 PF15101.6 EAX97914.1 - 6.5 6.8 7.6 7 6.6 7.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX97915.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX97916.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Metallophos PF00149.28 EAX97918.1 - 4.5e-24 86.1 0.1 6e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX97918.1 - 0.05 13.8 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 EAX97918.1 - 0.075 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) AAA_6 PF12774.7 EAX97919.1 - 1.4e-128 428.5 0.1 1.4e-128 428.5 0.1 4.0 6 0 0 6 6 6 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EAX97919.1 - 2.4e-94 316.7 22.5 2.4e-94 316.7 22.5 8.1 8 2 0 8 8 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EAX97919.1 - 3.3e-55 186.6 4.3 3.3e-55 186.6 4.3 5.7 6 0 0 6 6 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 EAX97919.1 - 1.1e-48 165.8 0.4 1.1e-48 165.8 0.4 4.5 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EAX97919.1 - 6.5e-29 100.7 0.9 1.7e-22 79.8 0.0 4.9 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EAX97919.1 - 1e-28 100.2 0.0 4e-28 98.3 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 EAX97919.1 - 9.5e-26 90.7 1.9 9.5e-26 90.7 1.9 2.6 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 EAX97919.1 - 2.4e-25 89.1 0.0 1.7e-15 57.2 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 EAX97919.1 - 4.8e-24 85.0 12.5 4.8e-24 85.0 12.5 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EAX97919.1 - 2.6e-20 72.7 0.0 2.6e-19 69.5 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EAX97919.1 - 4.1e-06 27.3 1.8 4.1 7.8 0.0 6.1 7 0 0 7 7 6 1 AAA ATPase domain AAA PF00004.29 EAX97919.1 - 6.1e-06 26.7 9.1 0.32 11.4 0.0 6.8 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAX97919.1 - 0.0028 18.0 1.0 6.3 7.2 0.0 4.8 4 0 0 4 4 2 1 RNA helicase Mg_chelatase PF01078.21 EAX97919.1 - 0.0059 16.0 0.4 0.61 9.4 0.0 3.1 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EAX97919.1 - 0.0093 16.3 0.0 17 5.7 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EAX97919.1 - 0.0095 16.2 13.7 4.5 7.5 0.0 6.6 7 0 0 7 7 6 1 AAA domain AAA_33 PF13671.6 EAX97919.1 - 0.014 15.6 0.2 4.2 7.5 0.0 4.5 5 0 0 5 5 5 0 AAA domain IstB_IS21 PF01695.17 EAX97919.1 - 0.024 14.4 0.3 9.9 5.9 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein IMS PF00817.20 EAX97919.1 - 0.093 12.7 0.1 0.56 10.2 0.1 2.4 1 0 0 1 1 1 0 impB/mucB/samB family Trans_reg_C PF00486.28 EAX97919.1 - 0.098 12.7 0.2 5 7.3 0.1 3.3 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal AAA_24 PF13479.6 EAX97919.1 - 0.31 10.7 0.0 0.31 10.7 0.0 5.2 6 0 0 6 6 5 0 AAA domain Dynein_AAA_lid PF17852.1 EAX97919.1 - 3.7 7.6 10.9 0.11 12.6 0.5 4.1 4 0 0 4 4 4 0 Dynein heavy chain AAA lid domain Ank PF00023.30 EAX97920.1 - 0.00015 22.0 0.0 0.0041 17.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EAX97920.1 - 0.0009 19.8 0.1 0.025 15.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97920.1 - 0.0012 19.2 0.0 0.092 13.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAX97920.1 - 0.0068 17.0 0.0 0.065 13.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4061 PF13270.6 EAX97921.1 - 0.015 15.6 0.2 0.044 14.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Cluap1 PF10234.9 EAX97921.1 - 0.12 11.8 4.4 0.17 11.3 0.1 1.9 1 1 0 2 2 2 0 Clusterin-associated protein-1 DUF2120 PF09893.9 EAX97921.1 - 0.18 11.9 4.7 0.91 9.6 1.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Ank_4 PF13637.6 EAX97922.1 - 4.9e-59 196.0 22.7 6.3e-15 55.3 0.1 8.5 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX97922.1 - 2.8e-56 185.6 22.4 5.6e-10 39.2 0.1 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.7 EAX97922.1 - 9.4e-49 163.9 27.8 4.5e-16 59.2 0.7 6.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97922.1 - 1.9e-44 144.5 23.3 7.7e-08 32.0 0.0 9.9 10 1 1 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EAX97922.1 - 6.6e-42 141.0 27.4 6.7e-11 42.2 0.4 7.8 4 1 5 9 9 9 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX97922.1 - 1.6e-35 120.9 9.5 1.6e-35 120.9 9.5 4.8 3 2 1 5 5 5 1 Domain of unknown function (DUF3447) Mqo PF06039.15 EAX97922.1 - 0.0008 18.1 0.0 0.72 8.3 0.0 2.5 1 1 1 2 2 2 2 Malate:quinone oxidoreductase (Mqo) UPF0203 PF05254.12 EAX97922.1 - 0.34 11.2 5.7 0.18 12.1 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Ank_2 PF12796.7 EAX97923.1 - 2e-55 185.3 23.7 2.8e-17 63.1 0.3 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97923.1 - 3.6e-47 156.8 7.6 9.6e-08 32.2 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAX97923.1 - 2.3e-42 142.8 6.5 1.4e-12 47.8 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97923.1 - 3.6e-42 141.9 17.3 2.5e-12 46.8 0.5 4.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97923.1 - 5.3e-36 118.5 6.6 5.5e-07 29.4 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat PAZ_siRNAbind PF12212.8 EAX97923.1 - 0.0006 19.6 0.6 0.036 13.9 0.0 2.9 4 0 0 4 4 4 1 PAZ domain MetallophosN PF16371.5 EAX97923.1 - 0.0066 16.7 0.2 1.5 9.2 0.0 3.8 2 2 3 5 5 5 1 N terminal of Calcineurin-like phosphoesterase DUF3169 PF11368.8 EAX97924.1 - 0.025 14.1 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Orf78 PF06024.12 EAX97924.1 - 0.049 13.9 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TOM20_plant PF06552.12 EAX97924.1 - 0.08 12.7 0.4 0.096 12.4 0.4 1.1 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Amnionless PF14828.6 EAX97924.1 - 0.086 11.7 0.1 0.094 11.5 0.1 1.0 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 EAX97924.1 - 0.18 12.1 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR19-TM PF15176.6 EAX97924.1 - 0.25 11.4 0.5 0.32 11.0 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Cyt-b5 PF00173.28 EAX97925.1 - 3.9e-14 52.6 0.0 5.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C3HC4_4 PF15227.6 EAX97926.1 - 0.0002 21.4 2.7 0.00044 20.4 2.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAX97926.1 - 0.00039 20.4 4.0 0.00083 19.3 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAX97926.1 - 0.0044 16.8 4.6 0.0087 15.9 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX97926.1 - 0.012 15.9 3.8 0.024 15.0 3.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 EAX97926.1 - 0.024 14.8 0.4 0.043 13.9 0.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 EAX97926.1 - 0.13 12.1 1.6 0.24 11.3 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX97926.1 - 0.13 12.1 4.5 0.1 12.5 2.7 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Dof PF02701.15 EAX97926.1 - 0.18 11.9 0.2 0.87 9.8 0.1 2.0 2 0 0 2 2 2 0 Dof domain, zinc finger CALCOCO1 PF07888.11 EAX97927.1 - 1.9e-06 27.0 28.2 1.9e-06 27.0 28.2 3.7 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.6 EAX97927.1 - 1.6e-05 23.8 23.1 1.6e-05 23.8 23.1 4.6 2 1 2 5 5 5 2 AAA domain TPR_MLP1_2 PF07926.12 EAX97927.1 - 0.0023 18.0 11.8 0.0023 18.0 11.8 5.7 2 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 EAX97927.1 - 0.0053 17.1 11.2 0.0053 17.1 11.2 4.9 3 2 0 4 4 4 1 Zinc finger-containing protein UVR PF02151.19 EAX97927.1 - 0.0072 16.0 1.4 0.0072 16.0 1.4 4.8 4 0 0 4 4 4 2 UvrB/uvrC motif CENP-F_leu_zip PF10473.9 EAX97927.1 - 0.011 15.8 17.2 0.011 15.8 17.2 6.4 1 1 7 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.8 EAX97927.1 - 0.012 16.0 8.0 0.012 16.0 8.0 6.4 3 1 4 7 7 7 0 YlqD protein FAD_SOX PF18371.1 EAX97927.1 - 0.67 10.3 5.7 3.3 8.1 0.1 3.3 2 1 1 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DASH_Hsk3 PF08227.11 EAX97927.1 - 1.8 9.0 7.8 8.4 6.8 0.5 4.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Baculo_PEP_C PF04513.12 EAX97927.1 - 4.5 7.3 41.4 0.029 14.4 3.4 5.5 3 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ANAPC4_WD40 PF12894.7 EAX97928.1 - 1.1e-06 28.9 0.0 2 8.7 0.0 4.0 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX97928.1 - 0.03 15.2 6.5 4.3 8.4 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat ABC_tran PF00005.27 EAX97929.1 - 4e-25 88.9 0.0 6.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX97929.1 - 3.7e-11 42.7 30.0 5.6e-11 42.1 30.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAX97929.1 - 3e-06 27.3 2.3 0.035 13.9 0.4 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAX97929.1 - 0.012 16.1 0.3 0.012 16.1 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAX97929.1 - 0.031 14.0 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EAX97929.1 - 0.094 12.4 0.5 1.2 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EAX97929.1 - 0.17 12.2 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAX97929.1 - 0.36 10.2 4.9 0.44 9.9 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Kelch_4 PF13418.6 EAX97930.1 - 3e-14 52.7 4.8 0.0098 15.9 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX97930.1 - 1.2e-13 50.4 0.5 0.026 14.1 0.0 5.7 6 1 1 7 7 7 4 Kelch motif Kelch_6 PF13964.6 EAX97930.1 - 2.8e-13 49.6 5.0 0.002 18.4 0.1 5.1 3 2 2 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EAX97930.1 - 5.5e-12 45.4 0.8 0.066 13.2 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EAX97930.1 - 2.1e-10 40.1 0.6 0.00026 20.8 0.0 4.7 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 EAX97930.1 - 3.5e-09 36.7 1.0 0.0017 18.6 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain HtrL_YibB PF09612.10 EAX97930.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DNA_pol3_a_NII PF11490.8 EAX97931.1 - 0.0066 16.3 0.7 0.0066 16.3 0.7 2.4 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus II DUF3385 PF11865.8 EAX97932.1 - 0.064 13.2 0.4 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Ank_2 PF12796.7 EAX97933.1 - 2.3e-19 69.8 5.2 1.1e-09 38.7 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX97933.1 - 5.3e-14 51.0 4.5 0.022 15.3 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EAX97933.1 - 5.8e-10 39.5 3.2 0.0013 19.2 0.0 4.0 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97933.1 - 6.3e-07 29.6 1.2 0.25 11.7 0.0 4.8 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX97933.1 - 0.00095 19.5 3.2 2.8 8.5 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeat CTD PF12815.7 EAX97933.1 - 0.91 10.1 4.5 14 6.3 4.5 2.3 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 PTR PF12789.7 EAX97934.1 - 3.9e-48 161.3 32.7 1.6e-23 82.5 7.8 4.7 5 0 0 5 5 5 3 Phage tail repeat like MscS_porin PF12795.7 EAX97934.1 - 0.059 12.9 0.4 8 5.9 0.0 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Peptidase_C78 PF07910.13 EAX97934.1 - 0.074 12.5 3.1 18 4.7 0.1 3.5 3 1 1 4 4 4 0 Peptidase family C78 Halogen_Hydrol PF10112.9 EAX97934.1 - 0.18 11.8 2.5 11 6.0 0.1 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PH_TFIIH PF08567.11 EAX97934.1 - 0.54 10.6 4.8 31 5.0 0.2 3.7 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain CppA_C PF14507.6 EAX97934.1 - 0.66 10.7 4.4 1.7 9.4 0.3 2.8 3 0 0 3 3 3 0 CppA C-terminal HIP1_clath_bdg PF16515.5 EAX97934.1 - 2.7 8.6 7.2 16 6.1 0.9 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 EAX97934.1 - 7.4 6.6 9.7 1.2 9.2 5.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4116 PF13475.6 EAX97935.1 - 0.019 14.7 0.6 0.052 13.3 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX97936.1 - 0.02 15.3 0.7 0.042 14.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX97937.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX97938.1 - 0.069 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAX97940.1 - 1.2e-71 241.1 0.0 1.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97940.1 - 5.1e-36 124.3 0.0 7.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAX97940.1 - 3.8e-15 56.3 0.5 8.4e-15 55.2 0.3 1.7 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EAX97940.1 - 1.5e-11 44.1 0.0 2.4e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 EAX97940.1 - 3.8e-07 30.7 0.1 7.3e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.6 EAX97940.1 - 1.2e-06 28.5 0.1 3.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EAX97940.1 - 0.00023 21.5 2.1 0.08 13.4 0.3 2.5 1 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EAX97940.1 - 0.00075 19.7 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 EAX97940.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX97940.1 - 0.003 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX97940.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EAX97940.1 - 0.011 15.4 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX97940.1 - 0.012 14.4 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EAX97940.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain PH_13 PF16652.5 EAX97940.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DnaGprimase_HBD PF16730.5 EAX97941.1 - 0.24 11.5 4.7 0.19 11.9 0.3 3.1 3 1 1 4 4 4 0 DnaG-primase C-terminal, helicase-binding domain DUF2353 PF09789.9 EAX97942.1 - 0.0004 19.9 16.6 0.0004 19.9 16.6 3.3 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) ERM PF00769.19 EAX97942.1 - 6.2 6.6 53.2 0.29 10.9 20.0 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF3447 PF11929.8 EAX97943.1 - 6.6e-25 86.9 5.1 6.6e-25 86.9 5.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX97943.1 - 1.7e-09 38.1 1.0 6.6e-08 33.0 0.9 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97943.1 - 1e-08 35.2 0.1 7.6e-06 26.2 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX97943.1 - 3.4e-08 33.9 0.3 2.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97943.1 - 6.7e-07 29.5 0.7 0.0054 17.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97943.1 - 5.5e-06 26.3 0.4 0.0023 18.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Bromodomain PF00439.25 EAX97944.1 - 3.3e-23 81.6 0.1 7e-23 80.5 0.1 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX97944.1 - 0.0001 22.4 0.5 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation KAR PF15222.6 EAX97944.1 - 0.13 12.6 1.5 11 6.4 1.5 2.3 1 1 0 1 1 1 0 Kidney androgen-regulated TPR_2 PF07719.17 EAX97945.1 - 5.7e-18 63.5 7.9 0.00012 22.0 0.1 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAX97945.1 - 1.2e-15 56.5 8.7 0.00018 21.2 0.2 6.5 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAX97945.1 - 3.9e-13 48.5 7.2 0.0023 18.0 0.1 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAX97945.1 - 5e-11 42.1 3.0 0.028 14.1 0.1 4.9 4 0 0 4 4 4 3 TPR repeat TPR_14 PF13428.6 EAX97945.1 - 1.1e-10 41.4 0.0 0.08 13.8 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX97945.1 - 2.7e-10 39.9 13.2 0.0069 16.7 0.1 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAX97945.1 - 6e-10 39.5 0.0 0.17 12.5 0.0 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAX97945.1 - 2.8e-09 37.5 0.0 0.13 12.9 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 EAX97945.1 - 3e-07 30.0 0.7 0.021 14.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX97945.1 - 4.6e-07 30.0 0.6 1.3 9.3 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAX97945.1 - 2.6e-05 24.6 4.0 3.9 8.3 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAX97945.1 - 5.7e-05 22.9 0.1 0.88 9.7 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 EAX97945.1 - 0.006 16.5 2.5 1.6 8.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 EAX97945.1 - 0.06 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat MIT PF04212.18 EAX97945.1 - 0.072 13.2 0.0 28 4.9 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain fn2 PF00040.19 EAX97945.1 - 0.085 13.1 1.4 0.2 11.9 1.4 1.6 1 0 0 1 1 1 0 Fibronectin type II domain SNARE PF05739.19 EAX97946.1 - 5.3e-09 35.9 2.1 8.2e-09 35.3 0.3 2.3 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 EAX97946.1 - 0.0018 16.4 12.3 0.024 12.6 3.3 2.0 2 0 0 2 2 2 2 Prominin COG5 PF10392.9 EAX97946.1 - 0.0025 18.0 5.7 0.35 11.0 0.4 2.2 2 0 0 2 2 2 2 Golgi transport complex subunit 5 Use1 PF09753.9 EAX97946.1 - 0.0034 17.1 12.8 0.0041 16.9 1.8 2.3 2 1 0 2 2 2 1 Membrane fusion protein Use1 ETRAMP PF09716.10 EAX97946.1 - 0.019 15.1 0.1 0.038 14.1 0.1 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Glucos_trans_II PF14264.6 EAX97946.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII Syntaxin PF00804.25 EAX97946.1 - 0.049 13.3 22.5 0.021 14.5 16.9 2.4 2 1 0 2 2 1 0 Syntaxin DUF4618 PF15397.6 EAX97946.1 - 0.1 12.0 14.0 0.73 9.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 EAX97946.1 - 0.12 11.3 13.2 0.2 10.5 3.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein LPP PF04728.13 EAX97946.1 - 0.12 12.8 0.6 0.12 12.8 0.6 3.4 3 1 0 3 3 3 0 Lipoprotein leucine-zipper T2SSF PF00482.23 EAX97946.1 - 0.18 11.8 1.8 0.48 10.4 0.2 2.3 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Atg14 PF10186.9 EAX97946.1 - 0.45 9.5 12.5 3.2 6.8 12.5 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 EAX97946.1 - 0.52 10.7 17.1 1.9 8.9 1.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein MscS_porin PF12795.7 EAX97946.1 - 0.54 9.8 24.7 0.07 12.7 8.0 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4456 PF14644.6 EAX97946.1 - 0.55 9.9 10.2 3.1 7.5 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4456) Allexi_40kDa PF05549.11 EAX97946.1 - 0.78 9.2 8.7 0.58 9.6 1.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Mobilization_B PF17511.2 EAX97946.1 - 1 9.7 4.3 0.62 10.4 1.4 1.9 2 0 0 2 2 2 0 Mobilization protein B COG2 PF06148.11 EAX97946.1 - 1.1 9.3 8.5 7.8 6.6 0.5 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EAX97946.1 - 1.7 7.8 9.5 1.7 7.8 3.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 EAX97946.1 - 2.2 8.4 13.1 1.1 9.3 2.3 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 EAX97946.1 - 2.2 8.6 14.9 4.5 7.6 0.1 3.0 2 1 1 3 3 3 0 Tho complex subunit 7 DUF5082 PF16888.5 EAX97946.1 - 3 8.2 14.8 2.9 8.2 2.2 3.6 2 2 0 3 3 3 0 Domain of unknown function (DUF5082) PIN_8 PF18476.1 EAX97946.1 - 3.3 7.5 10.8 0.59 9.9 3.7 2.2 2 0 0 2 2 2 0 PIN like domain FlaC_arch PF05377.11 EAX97946.1 - 3.9 7.9 12.2 1.8 9.0 0.5 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2780 PF11075.8 EAX97946.1 - 4.4 7.4 10.6 6 7.0 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) DASH_Dam1 PF08653.10 EAX97946.1 - 4.7 7.1 7.1 13 5.6 0.6 3.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 YkyA PF10368.9 EAX97946.1 - 5.2 6.7 12.7 6.2 6.4 3.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein SKA2 PF16740.5 EAX97946.1 - 9.5 6.1 15.0 2 8.2 4.3 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 EAP30 PF04157.16 EAX97946.1 - 9.7 5.4 13.0 84 2.3 12.3 2.6 1 1 1 2 2 2 0 EAP30/Vps36 family GldM_N PF12081.8 EAX97946.1 - 9.8 6.2 12.2 1.1 9.3 5.2 2.2 1 1 1 2 2 2 0 GldM N-terminal domain LRR_5 PF13306.6 EAX97947.1 - 8.4e-20 71.0 12.5 1.2e-17 64.1 2.1 2.9 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EAX97947.1 - 0.087 13.0 5.9 0.11 12.7 0.8 3.5 3 2 1 4 4 4 0 FNIP Repeat Gly_rich PF12810.7 EAX97948.1 - 5e-36 124.9 21.6 6e-36 124.6 21.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Kelch_4 PF13418.6 EAX97948.1 - 1.3 9.1 6.2 12 5.9 0.4 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain NopRA1 PF16201.5 EAX97949.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 DUF2428 PF10350.9 EAX97950.1 - 0.00022 20.6 0.2 0.00047 19.5 0.2 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DUF3385 PF11865.8 EAX97950.1 - 0.055 13.4 4.8 0.39 10.6 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) RICTOR_V PF14668.6 EAX97950.1 - 0.24 11.6 2.7 29 5.0 0.0 3.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 EAX97950.1 - 9.3 6.2 16.1 1.6 8.7 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Metallophos PF00149.28 EAX97951.1 - 4.1e-26 92.7 0.1 5.7e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX97951.1 - 0.0029 17.8 0.0 0.0038 17.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_alpha PF05793.12 EAX97953.1 - 3.6 6.1 94.3 5.1 5.6 94.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 EAX97953.1 - 5.4 5.4 26.7 7.6 5.0 26.7 1.1 1 0 0 1 1 1 0 Macoilin family Ank_4 PF13637.6 EAX97955.1 - 2e-70 232.3 14.8 3.2e-10 40.3 0.1 11.3 4 2 7 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97955.1 - 7.7e-66 218.7 27.5 8.3e-15 55.1 1.4 6.9 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97955.1 - 8e-64 209.5 6.0 1.1e-06 28.8 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EAX97955.1 - 1e-57 191.4 23.5 1.7e-08 34.5 0.0 8.8 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97955.1 - 6.7e-57 182.8 14.5 5.4e-06 26.4 0.1 12.0 14 0 0 14 14 14 9 Ankyrin repeat DUF3447 PF11929.8 EAX97955.1 - 7e-41 138.0 3.7 7e-41 138.0 3.7 4.5 3 2 3 6 6 6 1 Domain of unknown function (DUF3447) DUF5064 PF16703.5 EAX97955.1 - 0.00017 22.1 2.4 1.1 9.8 0.3 3.5 1 1 3 4 4 4 3 Domain of unknown function (DUF5064) PAZ_siRNAbind PF12212.8 EAX97955.1 - 0.037 13.9 0.5 7.2 6.5 0.0 3.9 1 1 2 3 3 3 0 PAZ domain FIVAR PF07554.13 EAX97955.1 - 2.3 9.1 14.2 0.88 10.4 0.2 4.0 3 1 2 5 5 5 0 FIVAR domain Tctex-1 PF03645.13 EAX97956.1 - 1.9e-14 53.8 0.0 2.2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family CDC50 PF03381.15 EAX97957.1 - 3e-70 236.9 0.6 3.8e-70 236.6 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RIIa PF02197.17 EAX97958.1 - 5.8e-08 32.3 0.0 8.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 EAX97958.1 - 0.081 12.6 0.2 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Dpy-30 motif Ank_2 PF12796.7 EAX97959.1 - 4.3e-43 145.8 10.7 2.6e-13 50.4 0.3 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97959.1 - 2.3e-30 104.6 0.9 1.8e-09 37.9 0.0 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97959.1 - 7.8e-29 99.4 2.7 9.2e-09 35.4 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX97959.1 - 7.8e-29 98.8 3.6 7.1e-05 23.1 0.1 6.9 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAX97959.1 - 3.9e-26 88.2 2.8 0.008 16.6 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat BTB PF00651.31 EAX97959.1 - 0.057 13.7 1.4 0.14 12.4 1.4 1.7 1 0 0 1 1 1 0 BTB/POZ domain Phage_T7_Capsid PF05396.11 EAX97959.1 - 0.11 12.9 1.3 23 5.3 0.1 3.2 2 1 1 3 3 3 0 Phage T7 capsid assembly protein YbaB_DNA_bd PF02575.16 EAX97959.1 - 0.51 10.6 2.2 1.7 8.9 0.1 2.8 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family Pkinase PF00069.25 EAX97962.1 - 5.3e-56 189.9 0.0 6.1e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97962.1 - 9.6e-29 100.4 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX97962.1 - 0.00061 18.8 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX97962.1 - 0.0057 16.6 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX97962.1 - 0.006 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX97962.1 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAX97962.1 - 0.083 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cation_ATPase_C PF00689.21 EAX97963.1 - 0.29 10.8 13.1 0.33 10.6 12.3 1.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus EF-hand_7 PF13499.6 EAX97964.1 - 1.9e-24 85.9 3.8 1.4e-13 51.0 1.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX97964.1 - 1.3e-22 77.6 14.1 1.4e-08 33.7 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EAX97964.1 - 3.4e-20 70.2 11.1 9.1e-09 34.6 0.1 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EAX97964.1 - 6.4e-17 61.1 13.0 3.7e-09 36.3 0.6 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX97964.1 - 7.5e-15 53.7 8.4 1.1e-06 27.9 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EAX97964.1 - 3.7e-06 26.8 0.8 0.005 16.8 0.2 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EAX97964.1 - 1.1e-05 25.7 0.3 0.0042 17.4 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 EAX97964.1 - 0.01 16.1 0.9 1.4 9.3 0.2 2.8 1 1 2 3 3 3 0 EF-hand domain SurA_N_3 PF13624.6 EAX97964.1 - 0.012 15.4 1.0 0.56 10.0 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SUB1_ProdP9 PF18213.1 EAX97964.1 - 0.013 15.3 0.2 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 SPARC_Ca_bdg PF10591.9 EAX97964.1 - 0.021 15.1 0.6 6.7 7.1 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HTH_40 PF14493.6 EAX97964.1 - 0.026 15.0 0.9 3.3 8.2 0.2 2.3 1 1 0 2 2 2 0 Helix-turn-helix domain Caleosin PF05042.13 EAX97964.1 - 0.029 14.3 0.0 6.5 6.7 0.0 2.5 1 1 0 2 2 2 0 Caleosin related protein Phage_TAC_12 PF12363.8 EAX97964.1 - 0.034 14.6 1.1 0.058 13.8 0.0 1.9 3 0 0 3 3 2 0 Phage tail assembly chaperone protein, TAC YqeY PF09424.10 EAX97964.1 - 0.034 14.2 1.0 1.3 9.1 0.3 2.1 2 0 0 2 2 2 0 Yqey-like protein TerB PF05099.13 EAX97964.1 - 0.074 13.0 1.7 1.2 9.1 0.0 2.7 1 1 1 3 3 3 0 Tellurite resistance protein TerB Glycos_trans_3N PF02885.17 EAX97964.1 - 0.078 12.8 1.6 22 5.0 0.0 3.3 2 1 0 3 3 3 0 Glycosyl transferase family, helical bundle domain DUF3349 PF11829.8 EAX97964.1 - 0.099 13.4 0.7 11 6.9 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Rhodanese PF00581.20 EAX97966.1 - 9.5e-16 58.3 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain PMT PF02366.18 EAX97967.1 - 6.5e-35 120.9 11.2 6.5e-35 120.9 11.2 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX97967.1 - 1.8e-20 73.4 14.0 1.8e-20 73.4 14.0 3.0 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Prominin PF05478.11 EAX97968.1 - 0.051 11.5 3.4 0.067 11.1 3.4 1.1 1 0 0 1 1 1 0 Prominin Mem_trans PF03547.18 EAX97969.1 - 7e-15 54.3 9.0 7e-15 54.3 9.0 2.0 1 1 1 2 2 2 1 Membrane transport protein TM_helix PF05552.12 EAX97969.1 - 4.8 7.2 11.0 1.7 8.7 0.1 3.3 3 0 0 3 3 3 0 Conserved TM helix Ank_4 PF13637.6 EAX97970.1 - 4.5e-30 103.6 2.1 1.8e-10 41.1 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX97970.1 - 1.4e-24 85.4 3.7 7e-09 35.8 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAX97970.1 - 5.4e-22 78.2 3.7 5.7e-19 68.5 2.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97970.1 - 1.3e-19 70.0 1.4 3.6e-10 39.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97970.1 - 2.7e-19 67.2 3.8 4.4e-07 29.7 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Diphthami_syn_2 PF01902.17 EAX97970.1 - 0.037 13.5 0.1 1.5 8.3 0.0 2.0 1 1 1 2 2 2 0 Diphthamide synthase Phage_T7_Capsid PF05396.11 EAX97970.1 - 0.062 13.7 0.8 0.15 12.4 0.3 1.8 1 1 1 2 2 2 0 Phage T7 capsid assembly protein Ank_4 PF13637.6 EAX97971.1 - 1.4e-52 175.4 13.9 4.2e-14 52.7 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX97971.1 - 1.4e-49 164.5 3.4 2.5e-09 37.1 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.7 EAX97971.1 - 1.2e-41 141.2 13.8 1.1e-18 67.5 0.7 4.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX97971.1 - 2.4e-40 136.0 13.1 1.2e-11 44.6 0.2 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97971.1 - 1.3e-39 129.7 4.0 8.6e-08 31.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat BRCT PF00533.26 EAX97971.1 - 0.0004 20.7 0.1 0.45 10.9 0.0 3.1 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain AnkUBD PF18418.1 EAX97971.1 - 0.001 19.2 0.0 1.4 9.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin ubiquitin-binding domain Shigella_OspC PF06128.11 EAX97971.1 - 0.0012 18.7 2.6 0.092 12.5 0.4 2.9 2 1 1 3 3 3 2 Shigella flexneri OspC protein DUF3130 PF11328.8 EAX97971.1 - 0.0047 17.1 2.2 12 6.3 0.1 3.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3130 DUF3447 PF11929.8 EAX97971.1 - 0.12 12.4 10.1 1.2 9.1 0.5 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX97971.1 - 0.14 12.4 7.3 26 5.1 0.1 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF3718) CCDC84 PF14968.6 EAX97971.1 - 0.39 10.3 3.7 8.9 5.8 3.7 2.5 1 1 0 1 1 1 0 Coiled coil protein 84 Ank_4 PF13637.6 EAX97972.1 - 1e-62 207.7 13.9 3e-13 50.0 0.1 8.9 4 1 7 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX97972.1 - 9.3e-58 192.8 13.7 3.2e-14 53.3 0.3 6.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97972.1 - 5.5e-54 178.4 7.6 5.2e-06 26.7 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX97972.1 - 1.2e-46 156.2 4.8 5.8e-12 45.6 0.1 5.9 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97972.1 - 3e-42 137.8 9.1 1.7e-06 27.9 0.0 10.8 12 0 0 12 12 12 7 Ankyrin repeat DUF3447 PF11929.8 EAX97972.1 - 1.6e-30 104.9 4.5 1.6e-30 104.9 4.5 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX97972.1 - 9.4e-05 22.6 0.1 0.29 11.5 0.0 4.8 1 1 4 5 5 5 1 Pleckstrin homology domain DcpS_C PF11969.8 EAX97972.1 - 0.0008 19.9 2.5 6.2 7.3 0.0 4.1 4 0 0 4 4 4 1 Scavenger mRNA decapping enzyme C-term binding DUF3718 PF12514.8 EAX97972.1 - 0.0019 18.3 1.4 10 6.3 0.0 4.8 2 2 3 5 5 5 1 Protein of unknown function (DUF3718) GAF PF01590.26 EAX97973.1 - 0.032 14.8 0.0 1.5 9.5 0.0 2.8 3 0 0 3 3 3 0 GAF domain GAF_2 PF13185.6 EAX97973.1 - 0.16 12.2 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 GAF domain SLC35F PF06027.12 EAX97974.1 - 1.3e-35 123.4 29.1 2e-35 122.8 29.1 1.2 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX97974.1 - 1.2e-11 44.9 49.4 2.3e-06 27.8 16.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EAX97974.1 - 0.0038 16.5 7.2 0.0038 16.5 7.2 2.5 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EAX97974.1 - 0.023 13.9 28.2 0.044 13.0 28.2 1.4 1 1 0 1 1 1 0 UAA transporter family SLATT_1 PF18181.1 EAX97974.1 - 1.1 9.2 9.8 0.35 10.8 0.1 3.0 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Ank_2 PF12796.7 EAX97976.1 - 5.1e-43 145.6 14.4 2.7e-18 66.3 0.7 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97976.1 - 4.4e-34 116.4 1.1 1.7e-11 44.4 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97976.1 - 1.3e-27 95.5 7.0 5.8e-08 32.9 0.1 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97976.1 - 1.8e-26 89.3 2.0 0.0014 18.9 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAX97976.1 - 7.3e-25 86.3 0.7 0.0027 18.1 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Spc7 PF08317.11 EAX97976.1 - 5.4e-05 22.2 7.1 7.7e-05 21.7 7.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5082 PF16888.5 EAX97976.1 - 0.00023 21.4 9.4 0.00071 19.8 9.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) APG6_N PF17675.1 EAX97976.1 - 0.00033 21.2 5.3 0.00082 19.9 5.3 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region Filament PF00038.21 EAX97976.1 - 0.00052 19.7 6.5 0.00092 18.9 6.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein DUF724 PF05266.14 EAX97976.1 - 0.002 18.0 8.7 0.0038 17.1 8.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) ADIP PF11559.8 EAX97976.1 - 0.0025 17.9 8.5 0.0025 17.9 8.5 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Nsp1_C PF05064.13 EAX97976.1 - 0.0086 15.9 8.8 0.017 14.9 8.8 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Fib_alpha PF08702.10 EAX97976.1 - 0.011 16.0 9.8 0.011 16.0 9.8 2.8 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EAX97976.1 - 0.013 15.9 6.3 0.027 14.9 6.3 1.5 1 0 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 EAX97976.1 - 0.017 15.2 4.5 0.017 15.2 4.5 2.5 2 1 0 2 2 1 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 EAX97976.1 - 0.017 15.3 7.0 0.035 14.3 7.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EAX97976.1 - 0.018 14.1 9.4 0.028 13.5 9.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PI3K_P85_iSH2 PF16454.5 EAX97976.1 - 0.023 14.3 12.2 0.074 12.7 12.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nup54 PF13874.6 EAX97976.1 - 0.028 14.5 3.0 0.052 13.7 3.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-H PF05837.12 EAX97976.1 - 0.042 14.3 4.7 0.1 13.0 4.7 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 EAX97976.1 - 0.049 13.7 10.7 0.093 12.8 10.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WEMBL PF05701.11 EAX97976.1 - 0.071 11.8 6.5 0.1 11.3 6.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF16 PF01519.16 EAX97976.1 - 0.079 13.5 13.2 0.22 12.0 13.0 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3450 PF11932.8 EAX97976.1 - 0.087 12.1 8.3 0.15 11.4 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 EAX97976.1 - 0.1 12.2 12.5 0.16 11.6 10.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 EAX97976.1 - 0.14 12.0 13.9 0.18 11.6 5.3 2.7 1 1 1 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.11 EAX97976.1 - 0.16 12.5 8.6 0.063 13.8 4.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 EAX97976.1 - 0.18 11.4 3.4 0.33 10.5 3.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region NRBF2 PF08961.10 EAX97976.1 - 0.22 11.1 6.0 0.41 10.2 6.0 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Prefoldin_2 PF01920.20 EAX97976.1 - 0.24 11.4 11.9 0.44 10.5 5.4 3.3 1 1 2 3 3 3 0 Prefoldin subunit DUF4763 PF15960.5 EAX97976.1 - 0.51 9.6 10.9 0.53 9.5 8.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DSPc PF00782.20 EAX97976.1 - 0.56 10.0 10.6 0.21 11.4 0.2 3.4 1 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain PI_PP_I PF18363.1 EAX97976.1 - 0.59 10.3 7.7 1.1 9.5 6.0 2.4 1 1 1 2 2 1 0 Phosphoinositide phosphatase insertion domain DUF4407 PF14362.6 EAX97976.1 - 0.64 9.3 2.8 1 8.7 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_25 PF01183.20 EAX97976.1 - 0.75 10.0 8.5 2 8.6 0.1 3.3 3 1 0 3 3 3 0 Glycosyl hydrolases family 25 TolA_bind_tri PF16331.5 EAX97976.1 - 0.76 9.9 5.3 2.1 8.5 5.3 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation USP8_interact PF08941.10 EAX97976.1 - 1 9.1 4.7 1.4 8.7 3.0 2.0 2 0 0 2 2 2 0 USP8 interacting eIF3_N PF09440.10 EAX97976.1 - 1.1 9.7 7.6 5.2 7.5 7.6 2.1 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain FlaC_arch PF05377.11 EAX97976.1 - 1.6 9.2 13.3 89 3.6 12.0 3.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EAX97976.1 - 3.1 8.3 12.4 1.4 9.4 1.8 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 EAX97976.1 - 3.3 7.8 8.0 3.3 7.8 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EAX97976.1 - 4.4 7.8 15.9 0.41 11.1 9.8 2.5 2 1 1 3 3 2 0 Cell division protein ZapB bZIP_2 PF07716.15 EAX97976.1 - 4.9 7.3 15.9 2.4 8.3 0.8 3.2 2 1 1 3 3 3 0 Basic region leucine zipper YabA PF06156.13 EAX97976.1 - 5.9 7.6 13.5 2.4 8.8 9.0 2.6 2 1 1 3 3 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 EAX97976.1 - 6 7.2 19.7 0.43 10.9 7.0 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3781 PF12636.7 EAX97977.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) GPS2_interact PF15784.5 EAX97978.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX97978.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX97979.1 - 0.12 12.4 7.1 0.19 11.7 7.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX97979.1 - 9.3 6.7 6.5 13 6.2 6.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAX97980.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta YbaB_DNA_bd PF02575.16 EAX97980.1 - 0.12 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF2939 PF11159.8 EAX97981.1 - 0.0045 17.4 0.6 0.0051 17.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAX97982.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX97982.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAX97983.1 - 9.8e-41 138.1 0.8 2.3e-40 136.9 0.1 2.0 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX97985.1 - 4.4e-158 524.0 13.3 5.5e-158 523.7 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX97985.1 - 0.059 13.9 4.5 0.11 13.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX97985.1 - 0.65 10.5 3.6 4.9 7.7 0.3 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sel1 PF08238.12 EAX97987.1 - 3.1e-16 59.4 10.7 7.1e-05 23.3 0.0 8.6 8 1 0 8 8 8 2 Sel1 repeat TPR_16 PF13432.6 EAX97987.1 - 5.3e-08 33.4 0.4 0.011 16.3 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat Pkinase PF00069.25 EAX97987.1 - 1.8e-06 27.6 0.7 3.2e-05 23.4 0.7 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX97987.1 - 0.00045 19.6 0.2 0.095 12.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Fis1_TPR_N PF14852.6 EAX97987.1 - 0.0059 16.2 0.1 0.085 12.5 0.0 2.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_14 PF13428.6 EAX97987.1 - 0.039 14.8 4.2 19 6.4 0.0 6.3 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAX97987.1 - 0.078 13.3 1.2 0.42 10.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAX97987.1 - 0.089 13.3 9.5 0.32 11.5 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAX97987.1 - 0.16 12.2 9.9 0.16 12.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAX97987.1 - 0.26 11.2 1.7 1.3 9.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5610 PF18433.1 EAX97987.1 - 0.98 9.9 5.2 0.41 11.2 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) TPR_8 PF13181.6 EAX97987.1 - 7.2 7.1 18.0 15 6.1 0.2 6.7 7 1 1 8 8 8 0 Tetratricopeptide repeat Rhodanese PF00581.20 EAX97988.1 - 3.2e-10 40.5 0.0 3.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain S1-P1_nuclease PF02265.16 EAX97989.1 - 1.8e-31 109.9 0.0 2.1e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Ank_2 PF12796.7 EAX97990.1 - 3.2e-73 242.3 4.8 1.6e-16 60.6 0.1 4.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97990.1 - 3.4e-30 104.0 0.3 5.9e-11 42.7 0.0 5.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97990.1 - 2.1e-28 95.2 0.1 3.9e-05 23.7 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX97990.1 - 8.4e-27 92.9 0.3 9.5e-09 35.4 0.1 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX97990.1 - 1.2e-22 79.3 0.0 0.0018 18.6 0.0 6.9 6 1 0 6 6 6 6 Ankyrin repeat Spc29 PF17082.5 EAX97992.1 - 0.0059 16.5 1.6 0.0059 16.5 1.6 3.1 1 1 1 2 2 2 1 Spindle Pole Component 29 Spc7 PF08317.11 EAX97992.1 - 5.9 5.7 59.9 0.034 13.0 12.2 3.8 2 2 0 3 3 3 0 Spc7 kinetochore protein Exo_endo_phos PF03372.23 EAX97993.1 - 4.3e-07 29.7 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EII-Sor PF03609.14 EAX97993.1 - 0.075 12.4 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component WD40 PF00400.32 EAX97994.1 - 1.5e-12 47.8 2.8 0.00026 21.7 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX97994.1 - 2.3e-05 24.6 0.0 3.5 8.0 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 EAX97995.1 - 3.6e-55 184.5 21.2 1.9e-16 60.4 1.8 7.0 3 3 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX97995.1 - 3e-52 174.4 14.3 6.6e-12 45.7 0.1 8.7 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX97995.1 - 1.5e-49 164.3 17.6 1.1e-06 28.8 0.0 11.0 10 1 1 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 EAX97995.1 - 2.4e-39 132.9 19.4 1.5e-08 34.7 0.0 7.4 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97995.1 - 3.2e-37 122.3 11.6 0.00039 20.7 0.0 11.7 11 0 0 11 11 11 8 Ankyrin repeat DUF3447 PF11929.8 EAX97995.1 - 1.9e-34 117.4 4.0 1.9e-34 117.4 4.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) UQ_con PF00179.26 EAX97996.1 - 9.2e-40 135.5 0.0 1.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EAX97996.1 - 0.0022 17.7 0.1 0.0031 17.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Ribonucleas_3_3 PF14622.6 EAX97998.1 - 0.00028 21.0 0.0 9.2 6.4 0.0 3.9 2 2 1 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EAX97998.1 - 0.17 12.5 0.1 7.9 7.2 0.0 3.1 3 1 1 4 4 4 0 Ribonuclease III domain Ank_2 PF12796.7 EAX97999.1 - 9.5e-47 157.5 20.8 2.9e-16 59.8 2.1 5.1 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX97999.1 - 3.4e-46 153.7 9.1 1.2e-08 35.0 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAX97999.1 - 8.3e-46 153.8 11.4 9.9e-11 42.0 0.2 8.6 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX97999.1 - 2.5e-42 142.4 9.9 1.5e-11 44.3 0.1 5.5 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX97999.1 - 1.6e-38 126.3 15.2 3.1e-06 27.1 0.1 9.2 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 EAX97999.1 - 5.1e-37 125.7 6.9 5.1e-37 125.7 6.9 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX97999.1 - 0.011 16.0 0.2 18 5.7 0.0 4.0 3 1 0 4 4 4 0 N terminal of Calcineurin-like phosphoesterase ThiS-like PF14453.6 EAX97999.1 - 0.04 13.9 8.6 2.1 8.5 0.1 5.2 3 2 3 6 6 6 0 ThiS-like ubiquitin DUF3718 PF12514.8 EAX97999.1 - 0.87 9.8 5.3 36 4.6 0.0 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF3718) Sigma70_r4_2 PF08281.12 EAX97999.1 - 2.5 7.8 3.8 44 3.9 0.0 4.2 6 0 0 6 6 6 0 Sigma-70, region 4 MULE PF10551.9 EAX98000.1 - 4.3e-10 39.9 0.2 1e-09 38.6 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX98000.1 - 0.0088 15.8 0.4 0.16 11.7 0.0 2.1 1 1 1 2 2 2 1 Transposase Transposase_mut PF00872.18 EAX98000.1 - 0.01 14.7 0.9 0.019 13.9 0.4 1.7 1 1 1 2 2 2 0 Transposase, Mutator family FAR1 PF03101.15 EAX98000.1 - 0.093 13.4 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain UDPG_MGDP_dh_N PF03721.14 EAX98001.1 - 4.3e-57 192.7 0.1 8e-57 191.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EAX98001.1 - 4.7e-35 120.2 0.2 1.2e-33 115.7 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EAX98001.1 - 7e-31 106.3 0.0 1.5e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 EAX98001.1 - 0.0006 20.0 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EAX98001.1 - 0.0095 16.2 0.1 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EAX98001.1 - 0.025 14.7 0.6 0.21 11.6 0.0 2.6 2 2 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain XPG_N PF00752.17 EAX98001.1 - 0.083 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain Dzip-like_N PF13815.6 EAX98002.1 - 4.2e-07 29.9 0.2 4.2e-07 29.9 0.2 5.3 5 0 0 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 EAX98002.1 - 0.0081 16.9 1.6 0.018 15.8 1.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger LRR_6 PF13516.6 EAX98003.1 - 1.1e-12 46.9 8.0 0.37 11.0 0.0 9.6 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EAX98003.1 - 5.5e-06 26.2 9.6 12 6.9 0.1 7.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 EAX98003.1 - 0.0035 17.7 23.5 3.7 8.1 0.0 7.3 6 3 2 9 9 9 4 Leucine Rich repeats (2 copies) UBA_3 PF09288.10 EAX98003.1 - 0.074 12.9 1.2 4.3 7.2 0.2 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain LRR_8 PF13855.6 EAX98003.1 - 6.1 6.7 15.4 16 5.3 0.5 6.0 6 2 0 6 6 6 0 Leucine rich repeat Frataxin_Cyay PF01491.16 EAX98004.1 - 3e-22 78.7 0.1 3.4e-22 78.6 0.1 1.0 1 0 0 1 1 1 1 Frataxin-like domain DUF4107 PF13389.6 EAX98006.1 - 3.3e-50 170.4 1.6 3.8e-50 170.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF963 PF06131.11 EAX98007.1 - 0.9 9.0 4.2 1.2 8.6 1.4 2.5 2 1 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Pox_A32 PF04665.12 EAX98009.1 - 1.3e-07 31.3 2.2 2.6e-07 30.4 0.2 2.1 1 1 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX98009.1 - 0.05 13.8 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX98009.1 - 0.062 12.9 0.3 2 8.0 0.3 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) KilA-N PF04383.13 EAX98010.1 - 4.5e-11 42.6 0.2 9e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain GPS2_interact PF15784.5 EAX98013.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98013.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAX98015.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain KilA-N PF04383.13 EAX98016.1 - 1.1e-40 137.9 1.0 2.1e-40 137.0 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX98016.1 - 0.0054 16.9 0.1 0.017 15.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX98017.1 - 1.4e-39 136.0 5.0 2.1e-39 135.4 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) GalP_UDP_transf PF01087.22 EAX98017.1 - 0.3 11.5 2.0 2.5 8.5 0.9 1.9 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF3839 PF12943.7 EAX98018.1 - 1.8e-103 345.2 6.1 2e-103 345.0 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF5398 PF17376.2 EAX98018.1 - 0.18 12.4 1.9 0.43 11.2 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5398) Chal_sti_synt_N PF00195.19 EAX98019.1 - 0.042 13.3 0.3 0.078 12.4 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAX98019.1 - 3.7 7.4 8.0 10 5.9 8.0 1.7 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Amidase02_C PF12123.8 EAX98021.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98022.1 - 1.4e-71 239.8 3.4 1.9e-71 239.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Kelch_6 PF13964.6 EAX98025.1 - 3.1e-23 81.2 5.4 5.8e-07 29.6 0.1 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EAX98025.1 - 1.1e-20 73.4 12.5 3.6e-08 33.3 0.7 6.2 4 1 2 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EAX98025.1 - 1.2e-19 69.6 0.4 9e-09 34.8 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EAX98025.1 - 1.2e-14 54.2 5.1 4.7e-05 23.5 0.1 4.4 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAX98025.1 - 1.9e-13 50.1 11.7 4.3e-10 39.4 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 EAX98025.1 - 4.2e-13 48.7 4.0 1.6e-05 24.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Ank_2 PF12796.7 EAX98027.1 - 4.8e-37 126.4 1.4 7.3e-22 77.8 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98027.1 - 2e-28 98.4 0.1 4.1e-09 36.8 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98027.1 - 1.2e-26 92.0 0.0 5.8e-06 26.5 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX98027.1 - 1.3e-26 92.3 0.3 4.5e-07 30.0 0.1 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98027.1 - 6.1e-25 84.6 0.0 0.0016 18.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat DUF4618 PF15397.6 EAX98027.1 - 0.00077 19.0 1.1 0.029 13.8 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Med22 PF06179.12 EAX98027.1 - 0.055 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex Ank_5 PF13857.6 EAX98028.1 - 8.8e-09 35.5 0.0 3.5e-06 27.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98028.1 - 9.2e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98028.1 - 4.9e-07 30.2 0.0 6.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98028.1 - 0.00018 21.8 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX98028.1 - 0.00038 20.7 0.0 0.084 13.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat DUF4618 PF15397.6 EAX98029.1 - 0.00013 21.5 1.1 0.017 14.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) PLU-1 PF08429.11 EAX98029.1 - 0.0089 15.2 0.3 0.011 14.9 0.3 1.1 1 0 0 1 1 1 1 PLU-1-like protein Med22 PF06179.12 EAX98029.1 - 0.0093 16.2 0.4 0.012 15.8 0.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF4200 PF13863.6 EAX98029.1 - 0.025 15.0 2.1 0.037 14.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5106 PF17127.4 EAX98029.1 - 0.089 13.1 1.2 4.2 7.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5106) TPH PF13868.6 EAX98030.1 - 3.4 6.1 131.2 7.7 4.9 131.2 1.5 1 1 0 1 1 1 0 Trichohyalin-plectin-homology domain ABC2_membrane_3 PF12698.7 EAX98032.1 - 6.9e-31 107.6 25.7 9e-31 107.2 25.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EAX98032.1 - 8.2e-24 84.7 0.0 1.5e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EAX98032.1 - 0.00093 19.1 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EAX98032.1 - 0.027 15.0 0.1 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EAX98032.1 - 0.039 13.7 1.4 0.056 13.2 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 EAX98032.1 - 0.069 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 EAX98032.1 - 0.15 11.3 8.2 0.21 10.8 8.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 EAX98032.1 - 0.6 9.9 2.0 0.69 9.7 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.10 EAX98034.1 - 0.00045 19.8 0.1 0.01 15.3 0.0 2.2 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 EAX98034.1 - 0.00078 19.9 0.0 0.0019 18.6 0.0 1.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAX98034.1 - 0.0032 17.8 0.3 0.067 13.6 0.1 2.6 1 1 1 2 2 2 1 RNA helicase NACHT PF05729.12 EAX98034.1 - 0.0035 17.3 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 EAX98034.1 - 0.0066 16.5 0.6 0.36 10.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 EAX98034.1 - 0.016 14.6 0.0 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EAX98034.1 - 0.022 14.1 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1319 PF07028.11 EAX98034.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) AAA_24 PF13479.6 EAX98034.1 - 0.047 13.4 0.0 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAX98034.1 - 0.077 13.3 0.1 0.36 11.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAX98034.1 - 0.082 13.5 0.2 0.19 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX98034.1 - 0.25 10.9 0.0 0.58 9.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 EAX98035.1 - 9.5e-38 129.3 0.1 1.2e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX98035.1 - 1.8e-28 99.2 0.1 3e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX98035.1 - 4.1e-13 49.2 0.0 5.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX98035.1 - 1.4e-07 31.3 0.2 9.7e-07 28.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX98035.1 - 4.6e-07 29.9 0.2 0.015 15.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EAX98035.1 - 1.2e-06 28.5 0.9 7.2e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EAX98035.1 - 3.4e-06 27.1 0.0 5.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAX98035.1 - 0.00064 20.1 0.0 0.00094 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAX98035.1 - 0.00082 18.9 0.1 0.0077 15.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EAX98035.1 - 0.0022 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 EAX98035.1 - 0.0044 16.8 0.8 1.2 8.9 0.1 2.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAX98035.1 - 0.013 15.2 0.4 0.035 13.8 0.4 2.0 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EAX98035.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 EAX98035.1 - 0.013 14.6 0.0 0.043 13.0 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 EAX98035.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 EAX98035.1 - 0.022 14.4 0.5 5.6 6.5 0.4 2.4 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 EAX98035.1 - 0.085 12.0 1.0 2.4 7.2 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 EAX98035.1 - 0.13 12.6 0.3 0.28 11.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAX98035.1 - 0.17 11.4 0.1 2.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Poxvirus A32 protein ABC_tran PF00005.27 EAX98035.1 - 0.17 12.4 0.1 0.26 11.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.25 EAX98036.1 - 2.8e-49 167.8 0.1 4e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98036.1 - 1.6e-33 116.1 0.0 2.2e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX98036.1 - 5.4e-07 28.7 0.0 8.3e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX98036.1 - 5e-05 22.8 0.0 0.00035 20.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX98036.1 - 0.0037 16.3 0.5 0.011 14.7 0.1 1.8 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 EAX98036.1 - 0.17 11.8 0.0 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 EAX98037.1 - 8e-12 44.8 18.0 1.5e-11 43.9 18.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX98037.1 - 0.00052 20.3 20.5 0.0011 19.3 20.5 1.5 1 0 0 1 1 1 1 Ring finger domain pXO2-34 PF17362.2 EAX98038.1 - 0.02 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function dsRBD2 PF17842.1 EAX98038.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.1 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 SHIPPO-rpt PF07004.12 EAX98038.1 - 2.2 9.3 8.0 28 5.8 0.0 4.0 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat Pkinase PF00069.25 EAX98039.1 - 1e-52 179.1 0.0 1.2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98039.1 - 4.4e-20 72.0 0.0 5.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EAX98039.1 - 0.0001 22.0 0.3 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAX98039.1 - 0.00067 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase GDA1_CD39 PF01150.17 EAX98040.1 - 2e-30 105.8 1.1 2.7e-30 105.4 1.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2207 PF09972.9 EAX98042.1 - 2.6e-07 29.8 22.2 0.0039 16.0 1.1 3.7 2 1 0 3 3 3 3 Predicted membrane protein (DUF2207) Tweety PF04906.13 EAX98042.1 - 2.8e-06 26.3 1.0 2.8e-06 26.3 1.0 3.8 1 1 3 4 4 4 1 Tweety Apolipoprotein PF01442.18 EAX98042.1 - 5.7e-05 23.1 1.9 0.56 10.1 0.1 3.4 2 2 0 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EAX98042.1 - 0.00032 20.7 25.9 0.066 13.3 1.0 4.1 2 2 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 EAX98042.1 - 0.00035 20.6 8.6 0.51 10.3 0.3 3.7 3 1 0 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF842 PF05811.13 EAX98042.1 - 0.00041 20.0 10.6 0.17 11.6 2.6 3.5 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF842) SseC PF04888.12 EAX98042.1 - 0.0033 17.1 10.6 0.0033 17.1 10.6 3.4 2 2 1 3 3 2 1 Secretion system effector C (SseC) like family Wzy_C PF04932.15 EAX98042.1 - 0.0038 16.9 2.5 0.21 11.2 0.1 2.9 3 0 0 3 3 3 1 O-Antigen ligase RmuC PF02646.16 EAX98042.1 - 0.0074 15.5 2.0 0.0074 15.5 2.0 3.7 3 1 1 4 4 4 1 RmuC family Syntaxin_2 PF14523.6 EAX98042.1 - 0.0077 16.6 22.3 0.36 11.2 0.1 3.9 3 1 0 3 3 3 1 Syntaxin-like protein YtxH PF12732.7 EAX98042.1 - 0.011 16.3 18.0 0.98 10.0 0.5 4.6 2 2 1 3 3 3 0 YtxH-like protein Ykof PF07615.11 EAX98042.1 - 0.014 15.9 0.8 2.5 8.6 0.0 3.4 3 1 0 3 3 2 0 YKOF-related Family Muted PF14942.6 EAX98042.1 - 0.018 15.4 24.4 1 9.7 5.5 3.3 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein HSCB_C PF07743.13 EAX98042.1 - 0.028 14.9 6.9 3.7 8.1 0.1 4.4 2 2 2 5 5 5 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 EAX98042.1 - 0.036 13.6 5.0 0.48 9.9 0.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit HSBP1 PF06825.12 EAX98042.1 - 0.042 13.7 5.7 30 4.6 0.2 5.0 3 2 2 5 5 4 0 Heat shock factor binding protein 1 IL11 PF07400.11 EAX98042.1 - 0.054 13.1 1.8 1.3 8.7 0.1 2.7 3 0 0 3 3 2 0 Interleukin 11 DUF1479 PF07350.12 EAX98042.1 - 0.08 11.7 0.7 0.15 10.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) LPD39 PF18858.1 EAX98042.1 - 0.086 12.9 3.2 1.5 8.8 0.1 2.8 2 1 1 3 3 3 0 Large polyvalent protein associated domain 39 ApoLp-III PF07464.11 EAX98042.1 - 0.087 12.9 27.3 2 8.5 2.1 4.0 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PMC2NT PF08066.12 EAX98042.1 - 0.1 13.3 11.4 2.6 8.8 0.4 3.8 2 2 2 4 4 4 0 PMC2NT (NUC016) domain PIN_8 PF18476.1 EAX98042.1 - 0.11 12.4 18.8 0.47 10.3 9.4 2.7 2 1 0 2 2 2 0 PIN like domain Mis12 PF05859.12 EAX98042.1 - 0.12 12.5 4.4 6.8 6.7 0.6 3.2 2 1 0 2 2 2 0 Mis12 protein DUF4795 PF16043.5 EAX98042.1 - 0.13 11.9 20.9 1.6 8.3 5.2 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) COG2 PF06148.11 EAX98042.1 - 0.16 12.1 14.3 1.2 9.2 0.4 3.8 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 FAM25 PF15825.5 EAX98042.1 - 0.17 12.2 3.6 0.42 11.0 0.5 2.7 2 0 0 2 2 2 0 FAM25 family ANAPC4 PF12896.7 EAX98042.1 - 0.22 11.0 5.8 1.7 8.1 0.4 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF5304 PF17230.2 EAX98042.1 - 0.23 11.7 0.9 6.6 7.0 0.1 3.1 4 0 0 4 4 2 0 Family of unknown function (DUF5304) Vps39_2 PF10367.9 EAX98042.1 - 0.28 11.6 4.2 0.74 10.3 0.5 2.9 2 1 1 3 3 2 0 Vacuolar sorting protein 39 domain 2 Cob_adeno_trans PF01923.18 EAX98042.1 - 0.3 11.2 6.4 1.6 8.9 2.3 3.0 2 1 0 2 2 2 0 Cobalamin adenosyltransferase HBM PF16591.5 EAX98042.1 - 0.33 10.3 5.7 1.6 8.1 0.5 2.8 2 2 0 2 2 2 0 Helical bimodular sensor domain MCPsignal PF00015.21 EAX98042.1 - 0.37 10.6 14.0 0.71 9.7 1.7 3.5 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rep_fac_C PF08542.11 EAX98042.1 - 0.38 11.2 2.4 1.6 9.2 0.1 2.8 2 1 0 2 2 2 0 Replication factor C C-terminal domain DUF1804 PF08822.11 EAX98042.1 - 0.4 10.6 2.6 3.1 7.7 0.1 3.1 2 2 2 4 4 3 0 Protein of unknown function (DUF1804) WXG100 PF06013.12 EAX98042.1 - 0.4 10.9 1.8 5.6 7.3 0.1 3.3 3 0 0 3 3 2 0 Proteins of 100 residues with WXG DUF2959 PF11172.8 EAX98042.1 - 0.49 10.5 11.6 8.1 6.5 4.9 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Nmad5 PF18757.1 EAX98042.1 - 0.85 9.8 13.1 0.082 13.1 3.1 2.8 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 PRKCSH-like PF12999.7 EAX98042.1 - 1 9.1 18.1 0.4 10.5 0.7 3.3 2 2 2 4 4 4 0 Glucosidase II beta subunit-like DUF3086 PF11285.8 EAX98042.1 - 1.1 8.3 3.5 18 4.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Tup_N PF08581.10 EAX98042.1 - 1.3 9.3 5.0 0.89 9.9 1.0 2.6 2 0 0 2 2 2 0 Tup N-terminal BRE1 PF08647.11 EAX98042.1 - 1.7 8.7 18.7 0.79 9.8 1.9 3.1 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase GARP PF16731.5 EAX98042.1 - 1.8 8.2 8.0 3.2 7.4 2.8 2.7 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Snapin_Pallidin PF14712.6 EAX98042.1 - 2 8.9 12.0 1.4 9.4 1.2 3.7 2 2 1 3 3 3 0 Snapin/Pallidin DUF1640 PF07798.11 EAX98042.1 - 2.2 8.3 12.8 8.6 6.4 3.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) ING PF12998.7 EAX98042.1 - 2.3 8.9 15.5 7.3 7.2 0.8 3.5 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding ABC1 PF03109.16 EAX98042.1 - 2.3 8.4 5.0 2.1 8.5 0.2 3.0 3 0 0 3 3 3 0 ABC1 family HsbA PF12296.8 EAX98042.1 - 2.7 8.4 12.6 5.2 7.5 0.6 3.7 3 1 1 4 4 3 0 Hydrophobic surface binding protein A DUF4047 PF13256.6 EAX98042.1 - 3.8 7.7 15.9 3.8 7.7 6.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) DUF3450 PF11932.8 EAX98042.1 - 4 6.7 9.4 0.52 9.6 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EAX98042.1 - 4 7.5 19.1 2.1 8.4 3.6 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) OmpH PF03938.14 EAX98042.1 - 4.1 7.7 15.5 0.53 10.6 3.7 3.4 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 EAX98042.1 - 5.4 7.2 27.8 0.9 9.7 10.7 3.8 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family GLE1 PF07817.13 EAX98042.1 - 5.5 6.1 7.4 4.8 6.3 0.1 3.0 3 0 0 3 3 3 0 GLE1-like protein FlaG PF03646.15 EAX98042.1 - 6.2 7.1 16.2 8.4 6.6 0.2 3.9 3 1 0 3 3 3 0 FlaG protein MgtE PF01769.16 EAX98042.1 - 7.1 7.0 18.3 6.5 7.2 2.3 3.3 3 0 0 3 3 3 0 Divalent cation transporter E1-E2_ATPase PF00122.20 EAX98042.1 - 7.7 6.0 12.5 5.4 6.5 0.5 3.1 3 0 0 3 3 2 0 E1-E2 ATPase DUF2408 PF10303.9 EAX98042.1 - 7.8 7.1 13.9 3.5 8.2 3.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Nup54 PF13874.6 EAX98042.1 - 7.9 6.6 7.8 30 4.7 1.6 3.4 2 2 0 2 2 2 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 EAX98042.1 - 9.5 6.2 20.9 0.29 11.1 1.8 4.0 2 2 1 4 4 4 0 Laminin Domain II RNase_J_C PF17770.1 EAX98042.1 - 9.6 7.3 14.1 17 6.5 2.4 3.8 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF4106 PF13388.6 EAX98043.1 - 1.4e-277 920.5 17.7 1.4e-277 920.5 17.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4106) DnaJ PF00226.31 EAX98044.1 - 1.6e-06 28.1 0.2 8.3e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_17 PF13431.6 EAX98044.1 - 0.0031 17.8 1.3 49 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAX98044.1 - 0.0036 17.8 1.6 1.6 9.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAX98044.1 - 0.023 13.9 0.8 0.51 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_assoc PF14363.6 EAX98044.1 - 0.17 12.3 5.4 15 6.0 0.0 3.7 2 2 2 4 4 4 0 Domain associated at C-terminal with AAA Nucleoside_tran PF01733.18 EAX98046.1 - 1.3e-26 93.7 28.5 4.7e-19 68.9 8.3 2.8 1 1 2 3 3 3 2 Nucleoside transporter MatE PF01554.18 EAX98047.1 - 1.4e-28 99.6 21.8 8.8e-20 71.0 5.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EAX98047.1 - 2.8e-06 27.4 5.7 2.8e-06 27.4 5.7 3.5 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MbeD_MobD PF04899.12 EAX98048.1 - 0.00032 20.8 9.1 0.00032 20.8 9.1 8.0 5 2 3 9 9 9 2 MbeD/MobD like Spc7 PF08317.11 EAX98048.1 - 0.0007 18.6 23.9 0.0007 18.6 23.9 6.2 2 1 5 7 7 7 2 Spc7 kinetochore protein Leu_zip PF15294.6 EAX98048.1 - 0.0078 15.8 20.3 0.0078 15.8 20.3 5.6 1 1 3 5 5 5 3 Leucine zipper Lactamase_B_2 PF12706.7 EAX98049.1 - 2e-13 50.3 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAX98049.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EAX98050.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Ank_2 PF12796.7 EAX98051.1 - 3.6e-39 133.2 10.1 3.3e-18 66.0 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98051.1 - 2.6e-22 76.5 0.6 0.00041 20.6 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX98051.1 - 2.9e-21 75.5 2.5 4.2e-10 39.9 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX98051.1 - 6.6e-17 61.1 0.1 0.0023 18.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX98051.1 - 7.4e-16 58.0 0.3 4.7e-08 33.1 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SH3BGR PF04908.15 EAX98051.1 - 0.26 11.5 1.9 1.4 9.1 1.9 2.2 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ribosomal_S5 PF00333.20 EAX98052.1 - 1.1e-25 89.3 1.0 2.2e-25 88.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EAX98052.1 - 9.1e-21 73.1 0.0 1.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PBP_like PF12727.7 EAX98052.1 - 0.15 11.2 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 PBP superfamily domain DUF4107 PF13389.6 EAX98054.1 - 2e-71 239.4 3.6 2.9e-71 238.8 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX98055.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX98057.1 - 2e-157 521.9 13.1 2.6e-157 521.5 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX98057.1 - 3.2 8.3 7.8 1.9 9.0 0.7 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAX98057.1 - 3.8 8.1 6.0 1.3 9.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1043 PF06295.12 EAX98058.1 - 0.011 15.7 0.3 0.015 15.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CBM_15 PF03426.14 EAX98058.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF2939 PF11159.8 EAX98059.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX98060.1 - 0.013 15.5 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAX98062.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98062.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Dimer_Tnp_hAT PF05699.14 EAX98063.1 - 0.07 12.9 0.9 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region PG_binding_2 PF08823.11 EAX98063.1 - 0.077 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF87 PF01935.17 EAX98063.1 - 0.11 12.6 0.6 0.37 10.8 0.6 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain Alba PF01918.21 EAX98063.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 Alba Myb_DNA-binding PF00249.31 EAX98064.1 - 2.4e-22 78.9 2.4 3.7e-10 39.8 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98064.1 - 5.8e-14 52.1 2.3 1.2e-07 31.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX98064.1 - 0.0053 16.6 0.3 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAX98064.1 - 0.061 13.6 1.3 0.15 12.4 0.3 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.10 EAX98064.1 - 0.2 11.8 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EAX98064.1 - 0.25 11.7 4.4 0.96 9.9 0.7 2.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TTL PF03133.15 EAX98065.1 - 4.3e-62 209.9 1.8 2.4e-61 207.5 0.0 2.6 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX98065.1 - 3e-09 36.5 7.1 2e-05 24.0 0.0 4.8 4 1 1 5 5 5 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX98065.1 - 8.3e-08 31.8 0.8 0.0005 19.4 0.0 3.6 4 0 0 4 4 4 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX98065.1 - 0.00074 19.6 0.1 0.012 15.6 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAX98065.1 - 0.015 14.8 0.0 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Myb_DNA-binding PF00249.31 EAX98066.1 - 2.7e-26 91.5 0.0 5.3e-13 48.9 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98066.1 - 3.5e-21 75.2 0.5 5e-13 49.1 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX98066.1 - 5.7e-07 29.4 0.3 5.7e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAX98066.1 - 0.0024 18.2 0.2 0.68 10.4 0.1 2.4 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EAX98066.1 - 0.0085 16.3 1.2 2.3 8.4 0.1 3.0 1 1 1 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EAX98066.1 - 0.015 15.3 0.1 1.5 8.9 0.0 2.7 1 1 1 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 EAX98066.1 - 0.049 13.8 0.0 0.13 12.5 0.0 1.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 EF-hand_1 PF00036.32 EAX98067.1 - 2.8e-12 45.2 3.7 0.00023 20.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EAX98067.1 - 2.9e-10 39.1 3.1 9.1e-05 21.8 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EAX98067.1 - 3.4e-10 40.2 12.9 6.7e-06 26.5 0.7 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EAX98067.1 - 4.2e-08 32.9 1.4 0.0035 17.2 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAX98067.1 - 7e-08 31.8 7.9 0.02 14.8 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.9 EAX98067.1 - 0.0012 19.1 2.7 0.14 12.5 2.7 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region CAP_GLY PF01302.25 EAX98067.1 - 0.11 12.6 0.1 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 CAP-Gly domain Dockerin_1 PF00404.18 EAX98067.1 - 0.32 11.2 2.0 0.57 10.4 0.0 2.3 2 1 0 2 2 2 0 Dockerin type I domain DUF4106 PF13388.6 EAX98068.1 - 4.8e-254 843.0 16.9 4.8e-254 843.0 16.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX98068.1 - 0.067 13.5 2.3 1.3 9.3 0.1 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated PSP PF04046.16 EAX98069.1 - 0.096 12.6 1.3 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98070.1 - 0.022 15.2 3.0 11 7.2 0.2 3.5 3 0 0 3 3 3 0 TMP repeat Antimicrobial_2 PF08023.12 EAX98070.1 - 0.19 12.3 0.2 7.7 7.1 0.2 2.3 1 1 0 1 1 1 0 Frog antimicrobial peptide ActA PF05058.12 EAX98072.1 - 4.5e-05 22.0 0.7 7.1e-05 21.4 0.2 1.6 2 0 0 2 2 2 1 ActA Protein PTR PF12789.7 EAX98072.1 - 0.00023 21.1 3.5 0.00029 20.8 0.2 2.9 3 0 0 3 3 3 1 Phage tail repeat like DUF4795 PF16043.5 EAX98072.1 - 0.026 14.1 0.3 0.026 14.1 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAX98072.1 - 0.03 14.0 0.4 0.38 10.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) SlyX PF04102.12 EAX98072.1 - 0.037 14.6 1.2 6.4 7.5 0.2 3.8 1 1 2 3 3 3 0 SlyX Bcr-Abl_Oligo PF09036.10 EAX98072.1 - 0.04 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1192 PF06698.11 EAX98072.1 - 0.23 11.5 3.9 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CEP209_CC5 PF16574.5 EAX98072.1 - 4.9 7.3 13.4 0.78 9.9 4.1 3.6 3 1 0 3 3 3 0 Coiled-coil region of centrosome protein CE290 Syntaxin-6_N PF09177.11 EAX98072.1 - 5.8 7.5 8.9 3 8.4 2.0 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EAX98073.1 - 0.016 15.2 4.7 0.021 14.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nckap1 PF09735.9 EAX98073.1 - 0.047 11.7 4.6 0.048 11.6 4.6 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DUF5077 PF16871.5 EAX98073.1 - 0.083 12.8 4.8 0.11 12.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) DUF4330 PF14221.6 EAX98073.1 - 0.11 12.7 2.3 0.13 12.5 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) PH_11 PF15413.6 EAX98073.1 - 0.13 12.7 1.4 0.16 12.4 1.4 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Zip PF02535.22 EAX98073.1 - 2.1 7.5 5.0 2.3 7.4 5.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 EAX98073.1 - 3.5 7.2 15.9 3.7 7.1 15.9 1.1 1 0 0 1 1 1 0 Spt20 family Myosin_TH1 PF06017.13 EAX98074.1 - 0.0014 18.4 0.6 0.0026 17.5 0.6 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding LRR_4 PF12799.7 EAX98074.1 - 0.0093 16.4 4.0 0.23 12.0 0.1 4.1 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 EAX98075.1 - 2.3e-11 44.1 21.8 2.3e-11 44.1 21.8 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Ank_4 PF13637.6 EAX98076.1 - 3.7e-14 52.9 1.2 8.9e-08 32.5 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98076.1 - 4.6e-12 46.4 1.1 7.6e-12 45.7 1.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98076.1 - 1e-09 37.8 0.1 0.00046 20.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAX98076.1 - 1.5e-08 34.7 0.1 1.6e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX98076.1 - 2.9e-06 27.4 0.2 0.059 13.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98076.1 - 6.4e-05 22.8 7.3 0.0047 16.9 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) DUF5095 PF17016.5 EAX98076.1 - 0.13 11.9 4.8 0.2 11.3 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5095) Methyltransf_23 PF13489.6 EAX98077.1 - 4.7e-17 62.3 0.0 6.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX98077.1 - 6e-15 55.4 0.0 8.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX98077.1 - 2.1e-13 50.9 0.1 4.2e-13 49.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX98077.1 - 1.8e-11 44.5 0.0 4.4e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX98077.1 - 3.5e-11 43.7 0.0 6.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAX98077.1 - 3.3e-08 33.2 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EAX98077.1 - 1.3e-07 31.3 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EAX98077.1 - 1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EAX98077.1 - 3.8e-05 23.2 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 EAX98077.1 - 4.6e-05 22.8 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.11 EAX98077.1 - 0.0012 17.8 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 EAX98077.1 - 0.0031 16.6 0.1 0.011 14.8 0.0 1.8 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EAX98077.1 - 0.0032 17.5 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EAX98077.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EAX98077.1 - 0.029 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.15 EAX98077.1 - 0.07 12.8 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MetW PF07021.12 EAX98077.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ank_2 PF12796.7 EAX98078.1 - 7.7e-33 112.9 15.0 5.9e-14 52.4 1.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98078.1 - 4.4e-29 100.1 6.8 2.9e-12 46.6 0.1 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX98078.1 - 3.7e-27 94.4 6.8 6.5e-12 45.7 0.2 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98078.1 - 6.7e-26 87.5 8.3 4.5e-05 23.5 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAX98078.1 - 2.4e-22 78.3 4.8 4.9e-05 23.6 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EAX98078.1 - 2.4e-12 46.6 28.7 4.2e-12 45.8 1.0 4.3 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) Sugar_tr PF00083.24 EAX98079.1 - 1.3e-55 189.0 42.5 9.5e-54 183.0 42.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX98079.1 - 3.5e-24 85.4 32.5 1e-14 54.3 7.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX98079.1 - 2.6e-05 23.0 28.8 0.0017 17.0 5.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Ank_2 PF12796.7 EAX98080.1 - 2.4e-56 188.3 24.6 2.7e-17 63.1 1.5 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98080.1 - 6e-43 144.7 4.3 4.1e-10 40.0 0.0 6.5 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98080.1 - 4.7e-42 141.5 4.9 2.1e-11 43.8 0.1 7.7 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAX98080.1 - 2.5e-35 119.4 14.8 1.2e-06 28.7 0.0 8.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 EAX98080.1 - 1.2e-33 111.3 11.9 0.0024 18.2 0.1 9.9 10 0 0 10 10 10 7 Ankyrin repeat LRR_5 PF13306.6 EAX98081.1 - 3.1e-90 298.7 86.2 1.1e-19 70.7 6.4 5.1 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) CHASE5 PF17149.4 EAX98081.1 - 0.049 13.6 0.3 36 4.3 0.0 5.3 7 0 0 7 7 7 0 Periplasmic sensor domain found in signal transduction proteins DUF2935 PF11155.8 EAX98082.1 - 0.00056 20.2 3.7 0.84 10.0 0.0 3.6 2 2 1 3 3 3 2 Domain of unknown function (DUF2935) Flg_hook PF02120.16 EAX98082.1 - 0.0086 15.9 2.6 0.34 10.8 1.1 3.0 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK HSBP1 PF06825.12 EAX98082.1 - 0.077 12.9 13.0 2.1 8.3 0.1 5.8 6 0 0 6 6 6 0 Heat shock factor binding protein 1 CLZ PF16526.5 EAX98082.1 - 0.33 11.3 0.1 0.33 11.3 0.1 5.9 4 3 2 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Plasmid_RAQPRD PF09686.10 EAX98082.1 - 0.39 11.0 0.1 0.39 11.0 0.1 3.7 4 1 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) FAM25 PF15825.5 EAX98082.1 - 0.67 10.3 2.9 0.99 9.8 0.3 2.5 2 1 0 2 2 2 0 FAM25 family Baculo_PEP_C PF04513.12 EAX98082.1 - 0.91 9.6 37.4 2.8 8.0 10.6 4.8 1 1 2 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gp-FAR-1 PF05823.12 EAX98082.1 - 1.2 9.5 29.8 0.51 10.7 4.2 4.3 2 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OmpH PF03938.14 EAX98082.1 - 1.4 9.2 43.6 0.023 15.1 9.0 4.0 1 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Vpu PF00558.19 EAX98082.1 - 2.9 7.7 7.1 22 4.9 0.2 3.3 2 0 0 2 2 2 0 Vpu protein DUF4349 PF14257.6 EAX98082.1 - 4.6 6.6 17.0 0.029 13.8 3.8 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4349) Fib_alpha PF08702.10 EAX98082.1 - 7.1 6.8 41.6 0.35 11.0 2.9 3.9 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 EAX98084.1 - 7.4e-76 250.8 35.2 2.8e-19 69.5 2.2 7.6 3 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98084.1 - 3.8e-66 218.6 12.7 2.2e-10 40.8 0.0 12.5 6 2 8 14 14 14 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX98084.1 - 2e-59 195.6 16.3 7.5e-09 35.6 0.0 13.0 13 0 0 13 13 13 8 Ankyrin repeat Ank_3 PF13606.6 EAX98084.1 - 8.4e-56 179.4 21.7 3.6e-05 23.8 0.1 15.4 17 0 0 17 17 17 11 Ankyrin repeat Ank_5 PF13857.6 EAX98084.1 - 8.7e-53 175.7 9.5 1.6e-09 37.8 0.0 9.8 5 2 4 10 10 10 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98084.1 - 1.4e-33 114.6 5.3 1.4e-33 114.6 5.3 8.4 3 1 7 10 10 10 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX98084.1 - 0.13 12.6 0.3 41 4.5 0.0 4.5 3 1 1 4 4 4 0 Pleckstrin homology domain Ank_2 PF12796.7 EAX98086.1 - 7.5e-15 55.3 2.0 9.2e-06 26.2 0.1 4.3 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX98086.1 - 2.1e-11 43.6 22.2 5.7e-11 42.2 0.2 5.8 4 2 3 7 7 7 3 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98086.1 - 7.4e-08 32.8 0.1 0.14 12.7 0.0 4.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98086.1 - 5.7e-07 29.4 0.5 0.22 12.2 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EAX98086.1 - 1.1e-05 25.6 0.0 0.23 11.8 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX98086.1 - 0.11 13.0 0.0 18 6.0 0.0 3.4 2 1 0 2 2 2 0 Ankyrin repeat Thioredoxin_11 PF18078.1 EAX98087.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain GSIII_N PF12437.8 EAX98090.1 - 5.2e-70 234.2 0.0 1.1e-69 233.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EAX98090.1 - 3.8e-41 139.6 5.0 3.8e-41 139.6 5.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EAX98090.1 - 2.6e-21 76.0 0.0 4.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SesA PF17107.5 EAX98090.1 - 0.0078 16.4 0.4 0.46 10.7 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin-6_N PF09177.11 EAX98090.1 - 0.028 15.0 0.6 0.096 13.3 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF724 PF05266.14 EAX98090.1 - 0.046 13.5 0.7 0.11 12.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) KIP1 PF07765.12 EAX98090.1 - 0.32 11.1 3.7 0.24 11.5 0.4 2.4 2 0 0 2 2 2 0 KIP1-like protein DUF4094 PF13334.6 EAX98090.1 - 0.47 10.9 3.0 3.6 8.1 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 EAX98090.1 - 0.62 10.2 2.8 1.2 9.3 1.8 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Interferon PF00143.19 EAX98090.1 - 1.7 8.8 4.0 7.3 6.8 0.5 2.4 1 1 1 2 2 2 0 Interferon alpha/beta domain ZapB PF06005.12 EAX98090.1 - 8.4 6.9 7.6 1.2 9.6 1.6 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF4108 PF13390.6 EAX98091.1 - 2.2e-63 212.5 6.4 2.4e-63 212.3 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) GGDEF PF00990.21 EAX98092.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Ly49 PF08391.10 EAX98092.1 - 1.1 9.7 4.9 1.4 9.3 4.9 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Gly-zipper_Omp PF13488.6 EAX98094.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX98094.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX98094.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Ank_2 PF12796.7 EAX98095.1 - 2.6e-11 44.0 0.9 0.0013 19.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98095.1 - 1.4e-10 41.5 2.1 0.07 13.7 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98095.1 - 2.8e-08 33.4 2.8 0.31 11.7 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX98095.1 - 1.2e-07 31.9 0.2 0.051 13.9 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Amidohydro_1 PF01979.20 EAX98095.1 - 0.028 13.7 0.0 0.066 12.5 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase family Ank PF00023.30 EAX98095.1 - 0.036 14.5 0.8 3.5 8.2 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat PfkB PF00294.24 EAX98095.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Helicase_PWI PF18149.1 EAX98095.1 - 0.79 9.9 5.3 16 5.7 0.1 3.7 4 1 0 4 4 4 0 N-terminal helicase PWI domain Ank_2 PF12796.7 EAX98096.1 - 6.2e-15 55.6 2.6 1.7e-06 28.5 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98096.1 - 1.4e-10 41.5 1.2 0.033 14.8 0.0 5.3 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98096.1 - 1.4e-08 34.3 2.9 0.59 10.9 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAX98096.1 - 1.4e-05 25.2 0.2 1.2 9.6 0.0 4.4 3 3 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX98096.1 - 4.4e-05 23.7 0.1 11 6.6 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat PUB PF09409.10 EAX98096.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 PUB domain Cytidylate_kin PF02224.18 EAX98097.1 - 0.0066 16.2 0.2 0.0066 16.2 0.2 2.5 1 1 2 3 3 3 1 Cytidylate kinase Pdase_M17_N2 PF18295.1 EAX98097.1 - 0.05 13.9 0.2 0.05 13.9 0.2 2.8 2 1 1 3 3 3 0 M17 aminopeptidase N-terminal domain 2 Reg_prop PF07494.11 EAX98097.1 - 0.11 12.8 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Two component regulator propeller DASH_Hsk3 PF08227.11 EAX98097.1 - 0.37 11.2 9.4 2.2 8.7 1.9 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Ribosomal_L12_N PF16320.5 EAX98097.1 - 0.49 10.1 2.9 2.3 8.0 2.9 2.2 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain AAA_13 PF13166.6 EAX98097.1 - 1.4 7.4 40.9 0.73 8.4 25.1 2.2 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 EAX98097.1 - 1.9 8.6 12.3 2.6 8.1 1.6 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EAX98097.1 - 2.2 7.6 38.0 0.87 8.9 18.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Herpes_UL92 PF03048.14 EAX98097.1 - 2.2 8.0 6.6 6.9 6.4 0.0 3.0 1 1 1 3 3 3 0 UL92 family Sec20 PF03908.13 EAX98097.1 - 8.7 6.3 11.6 0.15 12.0 2.5 2.7 2 1 0 2 2 2 0 Sec20 GSIII_N PF12437.8 EAX98098.1 - 1.7e-70 235.8 0.0 2.5e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.24 EAX98098.1 - 1.2e-20 73.9 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_C-ter PF18318.1 EAX98099.1 - 7.2e-44 148.4 5.8 7.2e-44 148.4 5.8 1.8 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain DUF724 PF05266.14 EAX98099.1 - 0.012 15.4 0.7 0.012 15.4 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 EAX98099.1 - 0.016 15.0 0.9 0.016 15.0 0.9 2.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 SesA PF17107.5 EAX98099.1 - 0.021 15.0 1.2 2 8.6 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Complex1_49kDa PF00346.19 EAX98099.1 - 0.045 12.8 1.5 0.11 11.5 1.4 1.9 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Mur_ligase_M PF08245.12 EAX98099.1 - 0.046 13.7 0.8 0.046 13.7 0.8 2.0 2 0 0 2 2 2 0 Mur ligase middle domain CRA_rpt PF07046.11 EAX98099.1 - 0.097 12.9 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Phage_int_SAM_3 PF14659.6 EAX98099.1 - 6.3 7.2 8.2 2 8.8 0.6 3.3 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain DUF4108 PF13390.6 EAX98100.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TPR_MLP1_2 PF07926.12 EAX98101.1 - 0.012 15.6 0.6 0.015 15.3 0.6 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX98101.1 - 0.058 13.2 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Adaptin_N PF01602.20 EAX98102.1 - 4.6e-82 276.3 2.3 6.2e-82 275.8 2.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX98102.1 - 1.8e-31 109.4 0.4 3.2e-30 105.3 0.4 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EAX98102.1 - 5.6e-18 65.1 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EAX98102.1 - 2.1e-09 37.7 3.2 0.00075 19.8 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EAX98102.1 - 4e-05 23.5 7.3 0.014 15.6 0.1 5.7 6 0 0 6 6 6 2 HEAT repeat Ribosomal_S19e PF01090.19 EAX98103.1 - 0.0058 16.3 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S19e DUF1600 PF07667.11 EAX98104.1 - 0.0079 16.4 0.4 0.0079 16.4 0.4 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1600) Sin3_corepress PF08295.12 EAX98105.1 - 1.7e-17 63.3 0.1 9.7e-17 60.9 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor RRM_1 PF00076.22 EAX98106.1 - 4.5e-06 26.4 0.0 0.0094 15.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX98106.1 - 0.00011 22.2 0.2 0.3 11.2 0.0 3.7 3 1 0 4 4 4 2 RNA recognition motif CagY_M PF07337.11 EAX98106.1 - 0.32 10.6 2.1 0.97 9.1 2.1 1.8 1 0 0 1 1 1 0 DC-EC Repeat PTR PF12789.7 EAX98107.1 - 7e-21 74.1 6.8 1.9e-16 59.8 1.9 5.6 6 1 1 7 7 7 2 Phage tail repeat like DUF4116 PF13475.6 EAX98107.1 - 0.095 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4795 PF16043.5 EAX98107.1 - 0.78 9.3 16.6 0.062 12.9 4.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 EAX98108.1 - 2.2e-38 130.7 6.5 8.3e-17 61.6 0.5 5.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98108.1 - 1.8e-36 124.1 3.4 2.6e-09 37.4 0.1 6.4 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX98108.1 - 4.2e-31 106.0 7.6 1.6e-06 28.3 0.0 9.0 8 1 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX98108.1 - 4e-30 100.5 8.7 0.00017 21.7 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX98108.1 - 9.6e-30 102.3 2.1 2.7e-10 40.3 0.1 7.0 1 1 6 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98109.1 - 1.4e-09 37.7 2.6 1.4e-09 37.7 2.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98110.1 - 1.4e-37 128.1 10.1 5e-13 49.5 1.9 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98110.1 - 3.3e-37 126.4 8.6 2e-09 37.8 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98110.1 - 2.3e-34 113.5 8.8 3.3e-06 27.0 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EAX98110.1 - 4.7e-27 93.2 11.0 4.2e-05 23.8 0.3 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX98110.1 - 8.5e-26 89.7 8.6 1.4e-07 31.6 0.1 5.1 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Peptidase_M16 PF00675.20 EAX98110.1 - 0.0013 18.7 0.4 5.2 7.0 0.0 3.4 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) DUF3718 PF12514.8 EAX98110.1 - 0.17 12.0 1.1 5 7.3 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3718) DUF3447 PF11929.8 EAX98111.1 - 3.5e-24 84.6 0.1 3.5e-24 84.6 0.1 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98111.1 - 0.001 19.6 0.0 0.0034 17.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Calici_PP_N PF08405.11 EAX98111.1 - 0.068 12.0 1.1 5.2 5.8 0.1 2.1 2 0 0 2 2 2 0 Viral polyprotein N-terminal PTR PF12789.7 EAX98112.1 - 3.3e-59 196.8 36.1 1.9e-32 111.1 16.2 4.3 2 2 2 4 4 3 2 Phage tail repeat like DUF1524 PF07510.11 EAX98112.1 - 1.7 8.5 14.3 9 6.2 8.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1524) DUF1493 PF07377.12 EAX98113.1 - 0.034 14.6 0.7 0.069 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) EF-hand_6 PF13405.6 EAX98114.1 - 6e-08 32.0 1.8 7.3e-07 28.6 1.2 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EAX98114.1 - 7.5e-07 28.3 1.8 1.4e-05 24.3 1.9 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EAX98114.1 - 9.8e-05 22.7 0.3 0.00015 22.2 0.3 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EAX98114.1 - 0.00018 21.3 1.4 0.00048 19.9 1.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EAX98114.1 - 0.00026 20.3 3.4 0.011 15.2 4.3 2.5 2 1 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 EAX98114.1 - 0.00088 19.1 0.2 0.0016 18.2 0.2 1.4 1 0 0 1 1 1 1 EF hand Methyltransf_23 PF13489.6 EAX98115.1 - 6.1e-10 39.2 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAX98115.1 - 1.4e-07 32.1 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX98115.1 - 1.9e-07 31.0 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAX98115.1 - 3.8e-06 27.5 0.0 5.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAX98115.1 - 2.4e-05 24.9 0.0 3.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EAX98115.1 - 0.00023 20.5 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EAX98115.1 - 0.00046 19.8 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EAX98115.1 - 0.0056 16.3 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Reovirus_L2 PF06016.11 EAX98115.1 - 0.067 10.4 0.0 0.08 10.1 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) DREV PF05219.12 EAX98115.1 - 0.12 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 DREV methyltransferase Peptidase_C2 PF00648.21 EAX98116.1 - 6.3e-37 127.2 0.6 1.1e-36 126.4 0.6 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease LRR_5 PF13306.6 EAX98117.1 - 6.9e-95 313.8 74.8 1.6e-24 86.3 0.1 6.3 4 2 2 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98117.1 - 2.5e-19 68.8 17.1 1.1e-06 28.3 0.2 8.6 6 2 5 11 11 11 5 Leucine rich repeat LRR_4 PF12799.7 EAX98117.1 - 0.0001 22.6 19.5 0.0033 17.8 0.1 7.1 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAX98117.1 - 0.002 18.3 12.4 1.4 9.1 0.0 7.0 8 0 0 8 8 8 1 FNIP Repeat OST_IS PF18246.1 EAX98117.1 - 0.13 12.5 0.1 28 5.1 0.0 3.5 3 1 0 3 3 3 0 Oligosaccharyltransferase Insert domain LRR_5 PF13306.6 EAX98118.1 - 9.8e-85 281.0 87.1 1.8e-24 86.1 2.5 6.4 4 2 2 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98118.1 - 1.9e-09 37.1 20.4 0.0025 17.5 0.2 8.1 6 3 3 9 9 9 4 Leucine rich repeat LRR_4 PF12799.7 EAX98118.1 - 5.8 7.5 20.4 34 5.0 3.0 6.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX98119.1 - 2.1e-28 98.9 34.9 2.1e-19 69.7 16.2 2.5 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98119.1 - 1.8e-07 30.8 2.1 0.00066 19.4 0.2 3.7 2 1 2 4 4 4 4 Leucine rich repeat TPR_MLP1_2 PF07926.12 EAX98120.1 - 0.0069 16.4 0.3 0.0088 16.1 0.3 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAX98120.1 - 2.1 8.3 10.5 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Guanylate_cyc PF00211.20 EAX98121.1 - 1.1e-41 142.5 0.2 3.5e-41 140.9 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX98121.1 - 1.1e-10 41.6 0.3 3.1e-10 40.2 0.3 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 EAX98121.1 - 0.013 14.9 0.3 0.028 13.9 0.3 1.5 1 0 0 1 1 1 0 Heme NO binding associated PAS_4 PF08448.10 EAX98121.1 - 0.094 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold TetR_C_8 PF14278.6 EAX98121.1 - 0.23 11.6 3.4 0.4 10.8 0.1 3.3 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Sec1 PF00995.23 EAX98122.1 - 1.1e-37 130.6 4.4 1.3e-36 127.0 4.4 1.9 1 1 0 1 1 1 1 Sec1 family Ank_5 PF13857.6 EAX98123.1 - 7.8e-18 64.3 0.3 3.6e-10 39.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98123.1 - 1.7e-16 60.6 1.6 1.9e-10 41.2 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98123.1 - 4.2e-16 59.1 0.5 8e-09 35.9 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98123.1 - 1.1e-14 53.0 3.8 0.00089 19.5 0.0 4.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EAX98123.1 - 7e-11 42.1 0.2 0.014 15.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DHC_N1 PF08385.12 EAX98124.1 - 0.00027 19.8 5.1 0.021 13.5 0.6 2.0 1 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 Fib_alpha PF08702.10 EAX98124.1 - 0.055 13.6 0.5 0.055 13.6 0.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cytochrom_B562 PF07361.11 EAX98124.1 - 0.065 13.9 0.5 0.065 13.9 0.5 2.8 1 1 1 2 2 2 0 Cytochrome b562 SLX9 PF15341.6 EAX98124.1 - 1.6 9.2 7.3 15 6.0 5.0 2.4 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 DHR10 PF18595.1 EAX98124.1 - 2.4 8.2 10.9 1.1 9.3 0.1 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF2408 PF10303.9 EAX98124.1 - 8.5 6.9 10.9 42 4.7 10.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) F_bP_aldolase PF01116.20 EAX98125.1 - 1.5e-92 310.0 0.0 2e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SRPRB PF09439.10 EAX98127.1 - 0.0012 18.3 0.6 0.21 11.0 0.0 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 EAX98127.1 - 0.0012 19.0 1.7 1.4 9.2 0.4 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EAX98127.1 - 0.0016 18.4 2.0 0.0034 17.3 2.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EAX98127.1 - 0.081 12.5 0.6 1.9 8.0 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAX98127.1 - 0.12 11.9 0.5 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EAX98127.1 - 0.13 12.4 1.3 2.7 8.1 0.1 2.3 1 1 1 2 2 2 0 50S ribosome-binding GTPase TMP PF05017.14 EAX98128.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX98129.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP RIO1 PF01163.22 EAX98130.1 - 1.7e-42 145.2 3.0 2e-42 145.0 0.1 2.0 1 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EAX98130.1 - 6.6e-28 96.8 0.1 1.3e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EAX98130.1 - 5.5e-07 29.8 0.6 0.0058 16.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EAX98130.1 - 6.9e-07 28.8 0.1 1.7e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAX98130.1 - 0.0019 17.6 0.3 0.0019 17.6 0.3 2.0 2 1 0 2 2 2 1 Protein kinase domain HrcA_DNA-bdg PF03444.15 EAX98130.1 - 0.014 15.0 0.3 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Pkinase_fungal PF17667.1 EAX98130.1 - 0.037 12.8 0.2 0.037 12.8 0.2 1.6 1 1 1 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EAX98130.1 - 0.35 10.1 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX98130.1 - 0.87 8.5 5.8 0.036 13.0 0.2 1.6 2 0 0 2 2 2 0 Haspin like kinase domain DUF3447 PF11929.8 EAX98131.1 - 1.8e-19 69.4 4.3 1.8e-19 69.4 4.3 4.6 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98131.1 - 8.5e-16 58.1 4.1 1.1e-10 41.8 0.8 3.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98131.1 - 2.4e-13 50.5 4.1 1.5e-12 48.0 1.0 2.7 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98131.1 - 3.6e-12 45.3 4.0 4.6e-05 23.5 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAX98131.1 - 1.9e-09 37.5 0.7 5.3e-05 23.5 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX98131.1 - 1.4e-08 34.8 2.9 0.00018 21.7 0.6 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3201 PF11447.8 EAX98131.1 - 0.044 13.3 1.0 0.13 11.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3201) RTBV_P12 PF06361.11 EAX98131.1 - 0.12 12.8 0.7 0.76 10.2 0.1 2.2 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Mt_ATP-synt_D PF05873.12 EAX98133.1 - 0.0031 17.4 0.5 0.0031 17.4 0.5 2.0 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) GNVR PF13807.6 EAX98133.1 - 0.013 15.4 0.4 0.035 14.0 0.4 1.7 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Nop PF01798.18 EAX98133.1 - 0.042 13.3 2.8 0.059 12.8 2.8 1.2 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Orthopox_F7 PF05813.12 EAX98133.1 - 0.16 12.1 0.6 0.36 11.0 0.6 1.6 1 0 0 1 1 1 0 Orthopoxvirus F7 protein TSP_NTD PF17804.1 EAX98133.1 - 1.3 9.3 8.3 1.9 8.7 8.3 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain MFS_1 PF07690.16 EAX98134.1 - 9.8e-19 67.5 48.5 2.1e-16 59.8 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAX98134.1 - 1.9e-13 49.8 22.7 1.9e-13 49.8 22.7 2.6 2 1 1 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 EAX98134.1 - 1.1e-06 28.0 2.8 1.1e-06 28.0 2.8 1.8 2 0 0 2 2 2 1 PUCC protein Ank_2 PF12796.7 EAX98135.1 - 1.8e-23 82.9 0.8 2.1e-08 34.6 0.0 6.3 4 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98135.1 - 7.8e-20 68.9 0.2 0.05 14.2 0.0 8.9 7 1 1 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EAX98135.1 - 1.5e-14 54.1 3.6 0.019 15.6 0.0 6.9 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98135.1 - 8.1e-10 38.8 0.0 1.3 9.5 0.0 6.6 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98135.1 - 1.7e-06 28.2 0.0 0.52 10.8 0.0 5.3 5 1 0 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 EAX98136.1 - 8.8e-09 35.2 0.1 8.8e-09 35.2 0.1 3.0 2 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX98136.1 - 0.00076 19.7 0.3 13 6.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98136.1 - 0.059 14.0 0.3 20 5.9 0.1 2.6 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98136.1 - 0.15 12.7 0.4 7.7 7.2 0.1 3.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HIP1_clath_bdg PF16515.5 EAX98137.1 - 1.4 9.6 7.6 0.65 10.6 3.8 2.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 EAX98137.1 - 3.2 7.0 9.9 0.34 10.2 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3447 PF11929.8 EAX98138.1 - 9.7e-13 47.9 9.3 9.7e-13 47.9 9.3 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98138.1 - 2.2e-08 34.6 5.1 0.00069 20.2 2.5 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98138.1 - 1.1e-06 29.1 2.9 0.0002 21.9 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98138.1 - 2.7e-06 27.5 1.2 0.4 11.1 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98138.1 - 0.00046 20.4 7.7 0.66 10.7 0.1 5.5 7 0 0 7 7 7 1 Ankyrin repeat SHIPPO-rpt PF07004.12 EAX98139.1 - 6.2e-08 33.2 3.3 0.041 14.8 0.1 4.1 3 0 0 3 3 3 2 Sperm-tail PG-rich repeat PI3_PI4_kinase PF00454.27 EAX98140.1 - 9.2e-36 123.9 0.3 5.1e-24 85.4 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EAX98140.1 - 6.8e-30 103.8 0.1 1.3e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EAX98140.1 - 7.9e-11 42.0 0.0 1.8e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Ank_2 PF12796.7 EAX98141.1 - 2.5e-245 793.9 190.2 5.5e-19 68.5 4.1 17.6 2 1 19 21 21 21 21 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98141.1 - 4.1e-229 732.2 82.0 5.8e-08 32.8 0.0 31.1 31 0 0 31 31 31 30 Ankyrin repeat Ank_4 PF13637.6 EAX98141.1 - 8.2e-226 727.8 91.8 1.6e-12 47.6 0.2 30.4 4 2 27 31 31 31 29 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98141.1 - 6.4e-184 573.0 64.2 5.1e-07 29.5 0.0 31.6 31 0 0 31 31 31 28 Ankyrin repeat Ank_5 PF13857.6 EAX98141.1 - 1.2e-178 576.8 132.2 2.5e-12 46.8 1.3 19.4 7 4 15 23 23 23 22 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98141.1 - 1.5e-35 121.0 10.7 1.5e-35 121.0 10.7 6.9 5 3 4 9 9 9 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX98141.1 - 1.4e-17 63.7 16.5 1.1 9.6 0.0 15.9 3 2 16 19 19 19 4 N terminal of Calcineurin-like phosphoesterase Ribosomal_S6 PF01250.17 EAX98141.1 - 0.0042 17.3 50.0 16 5.8 0.1 15.6 1 1 19 23 23 23 1 Ribosomal protein S6 PAZ_siRNAbind PF12212.8 EAX98141.1 - 0.0067 16.2 26.3 26 4.7 0.0 14.2 4 2 18 23 23 23 0 PAZ domain HEAT_EZ PF13513.6 EAX98142.1 - 1.2e-11 44.8 0.0 0.29 11.7 0.0 7.3 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 EAX98142.1 - 9.1e-11 41.1 9.6 0.1 12.9 0.0 9.2 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EAX98142.1 - 1.8e-10 41.0 0.0 0.067 13.6 0.0 5.4 2 2 4 6 6 6 5 HEAT repeats Adaptin_N PF01602.20 EAX98142.1 - 6.6e-09 34.9 6.2 7.9e-08 31.3 6.1 2.6 1 1 0 1 1 1 1 Adaptin N terminal region MMS19_C PF12460.8 EAX98142.1 - 5e-08 32.5 4.2 0.16 11.0 0.1 4.9 3 2 1 4 4 4 3 RNAPII transcription regulator C-terminal SF3b1 PF08920.10 EAX98142.1 - 2.2e-05 24.9 0.0 4.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 Dopey_N PF04118.14 EAX98142.1 - 0.00013 21.2 3.7 0.19 10.8 0.0 4.5 1 1 2 4 4 4 1 Dopey, N-terminal Cnd1 PF12717.7 EAX98142.1 - 0.00027 21.0 7.4 0.58 10.2 1.0 5.0 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EAX98142.1 - 0.00069 19.6 2.1 12 6.1 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 EAX98142.1 - 0.0012 18.8 0.4 0.021 14.8 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 EAX98142.1 - 0.0026 17.9 0.3 6.5 7.0 0.0 3.8 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EAX98142.1 - 0.0027 18.3 0.9 78 4.0 0.0 5.3 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EAX98142.1 - 0.025 14.2 0.8 1.5 8.2 0.0 3.6 4 0 0 4 4 4 0 Tti2 family Swm2 PF17083.5 EAX98142.1 - 1.3 9.1 4.6 4.7 7.2 0.8 2.8 2 0 0 2 2 2 0 Nucleolar protein Swm2 Mlp PF03304.13 EAX98142.1 - 2.2 8.5 4.5 1.4 9.1 0.7 2.2 2 0 0 2 2 2 0 Mlp lipoprotein family AAA_23 PF13476.6 EAX98144.1 - 7.8e-28 98.4 13.9 7.8e-28 98.4 13.9 5.6 1 1 2 3 3 1 1 AAA domain AAA_29 PF13555.6 EAX98144.1 - 1.4e-08 34.4 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX98144.1 - 7.4e-07 28.8 0.0 7.4e-07 28.8 0.0 4.8 3 1 2 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAX98144.1 - 1.8e-06 27.9 51.8 1.8e-06 27.9 51.8 3.3 1 1 2 3 3 1 1 AAA ATPase domain AAA_21 PF13304.6 EAX98144.1 - 2.5e-05 24.2 1.0 2.5e-05 24.2 1.0 4.0 1 1 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAX98144.1 - 0.0018 18.5 3.0 0.061 13.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Rad50_zn_hook PF04423.14 EAX98144.1 - 0.0039 17.0 6.9 0.0039 17.0 6.9 8.8 8 4 0 8 8 7 1 Rad50 zinc hook motif AAA_27 PF13514.6 EAX98144.1 - 0.0043 16.7 0.0 0.0043 16.7 0.0 4.7 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.6 EAX98144.1 - 0.0078 16.6 0.1 0.36 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Zn-C2H2_12 PF18112.1 EAX98144.1 - 0.023 15.2 0.4 0.083 13.4 0.4 2.0 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain AAA_30 PF13604.6 EAX98144.1 - 0.026 14.2 0.0 0.092 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 EAX98144.1 - 0.058 13.2 0.0 0.058 13.2 0.0 4.1 3 2 1 4 4 4 0 MukB N-terminal AAA_13 PF13166.6 EAX98144.1 - 0.092 11.4 97.9 3.2 6.3 0.0 4.6 2 1 3 5 5 5 0 AAA domain AAA_19 PF13245.6 EAX98144.1 - 0.38 11.1 3.5 0.38 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain zf-C2H2_11 PF16622.5 EAX98144.1 - 0.72 9.7 2.1 1.5 8.6 2.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type SMC_N PF02463.19 EAX98145.1 - 6.7e-06 25.7 0.2 7.4e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EAX98145.1 - 0.00037 20.7 0.0 0.00067 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SEFIR PF08357.11 EAX98145.1 - 0.047 14.0 0.2 0.072 13.4 0.2 1.4 1 0 0 1 1 1 0 SEFIR domain AAA_21 PF13304.6 EAX98145.1 - 0.058 13.2 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system LRR_6 PF13516.6 EAX98148.1 - 6.3e-05 22.7 0.7 1.5 9.0 0.0 4.2 3 0 0 3 3 3 2 Leucine Rich repeat Carm_PH PF17888.1 EAX98148.1 - 0.11 12.8 0.1 0.4 11.1 0.1 1.9 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_1 PF00560.33 EAX98148.1 - 4.3 8.3 9.9 65 4.7 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat AAA_23 PF13476.6 EAX98150.1 - 6.3e-21 75.8 42.1 6.3e-21 75.8 42.1 9.6 1 1 4 5 5 1 1 AAA domain AAA_29 PF13555.6 EAX98150.1 - 3.7e-06 26.6 0.0 7.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX98150.1 - 6.5e-06 25.7 0.1 6.5e-06 25.7 0.1 5.6 3 2 0 3 3 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAX98150.1 - 0.0024 17.7 0.0 0.0024 17.7 0.0 6.8 2 1 3 6 6 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EAX98150.1 - 0.0039 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EAX98150.1 - 0.011 16.1 0.0 0.076 13.4 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAX98150.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain Zn-C2H2_12 PF18112.1 EAX98150.1 - 0.057 13.9 0.4 0.15 12.5 0.4 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain ABC_tran PF00005.27 EAX98150.1 - 0.063 13.8 0.0 0.063 13.8 0.0 8.3 3 2 0 3 3 1 0 ABC transporter AAA_30 PF13604.6 EAX98150.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX98150.1 - 7.9 6.7 7.4 1.6 9.0 0.3 3.2 3 0 0 3 3 3 0 AAA domain Mcl1_mid PF12341.8 EAX98151.1 - 1.2e-46 159.4 0.0 3.1e-46 158.1 0.0 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region SBBP PF06739.11 EAX98151.1 - 0.033 14.2 4.8 5 7.2 0.1 3.5 3 0 0 3 3 3 0 Beta-propeller repeat PSP PF04046.16 EAX98152.1 - 0.073 12.9 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98153.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX98154.1 - 0.015 15.8 0.5 0.031 14.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX98155.1 - 8.2e-30 102.6 12.9 8.2e-30 102.6 12.9 4.5 5 1 0 5 5 5 1 Phage tail repeat like DUF4116 PF13475.6 EAX98155.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4116 PF13475.6 EAX98157.1 - 0.023 14.4 1.2 0.071 12.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF1493 PF07377.12 EAX98158.1 - 0.033 14.6 0.7 0.071 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX98159.1 - 0.013 15.8 4.2 2.9 8.9 0.3 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX98160.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Big_7 PF17957.1 EAX98161.1 - 3.5e-08 34.1 7.0 0.017 15.9 0.0 5.1 5 1 0 5 5 5 2 Bacterial Ig domain CHB_HEX_C_1 PF13290.6 EAX98161.1 - 0.00032 20.7 5.6 0.0065 16.5 0.1 3.5 4 0 0 4 4 4 2 Chitobiase/beta-hexosaminidase C-terminal domain PsbP PF01789.16 EAX98161.1 - 0.017 15.3 0.1 0.053 13.7 0.1 1.9 1 0 0 1 1 1 0 PsbP DUF2846 PF11008.8 EAX98161.1 - 0.03 14.3 0.2 0.68 10.0 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2846) TIG PF01833.24 EAX98161.1 - 0.17 11.9 2.9 67 3.7 0.1 5.1 5 3 0 5 5 5 0 IPT/TIG domain DUF4397 PF14344.6 EAX98161.1 - 0.21 12.4 3.2 3.1 8.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4397) TMEM154 PF15102.6 EAX98162.1 - 2.7e-07 30.6 4.7 3.5e-07 30.2 4.6 1.4 1 1 0 1 1 1 1 TMEM154 protein family SIT PF15330.6 EAX98162.1 - 2.4e-05 24.7 0.0 3.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4448 PF14610.6 EAX98162.1 - 0.0013 18.6 0.4 0.002 18.0 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EAX98162.1 - 0.0035 18.2 0.0 0.0058 17.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAX98162.1 - 0.0087 16.1 0.5 0.0087 16.1 0.5 1.8 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment Orf78 PF06024.12 EAX98162.1 - 0.01 16.1 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) PRIMA1 PF16101.5 EAX98162.1 - 0.011 15.8 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2207 PF09972.9 EAX98162.1 - 0.016 14.0 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.12 EAX98162.1 - 0.023 14.6 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Ninjurin TRP PF06011.12 EAX98162.1 - 0.025 13.3 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Protocadherin PF08374.11 EAX98162.1 - 0.04 13.9 0.1 0.057 13.4 0.1 1.3 1 1 0 1 1 1 0 Protocadherin DUF3827 PF12877.7 EAX98162.1 - 0.058 11.8 0.3 0.076 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF443 PF04276.12 EAX98162.1 - 0.094 12.5 2.6 0.06 13.2 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) OAD_gamma PF04277.13 EAX98162.1 - 0.13 12.9 0.8 0.34 11.5 0.1 2.0 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain EssA PF10661.9 EAX98162.1 - 0.14 12.0 4.8 1.5 8.7 0.7 2.2 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Mid2 PF04478.12 EAX98162.1 - 0.23 11.3 2.9 0.47 10.3 2.9 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor ETRAMP PF09716.10 EAX98162.1 - 0.23 11.5 1.8 0.29 11.2 1.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NCU-G1 PF15065.6 EAX98162.1 - 0.46 9.4 3.4 0.72 8.8 3.4 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF3377 PF11857.8 EAX98162.1 - 2.1 8.3 5.1 2.4 8.1 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) Dynamin_M PF01031.20 EAX98164.1 - 2.4e-84 282.9 0.1 5.1e-84 281.9 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EAX98164.1 - 1.1e-53 181.7 0.0 3.2e-53 180.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EAX98164.1 - 8.3e-21 74.0 0.5 2e-20 72.7 0.5 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAX98164.1 - 0.00029 20.9 0.1 0.0018 18.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mnd1 PF03962.15 EAX98164.1 - 0.31 11.4 1.5 26 5.2 0.0 3.0 3 0 0 3 3 3 0 Mnd1 HTH domain Pkinase PF00069.25 EAX98165.1 - 1.3e-55 188.6 0.0 1.5e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98165.1 - 4.8e-36 124.4 0.0 6.4e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98165.1 - 0.00093 18.6 0.0 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAX98165.1 - 0.002 18.1 0.0 0.037 13.9 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98165.1 - 0.0021 16.9 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX98165.1 - 0.015 14.9 0.2 0.25 10.9 0.1 2.0 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 EAX98165.1 - 0.03 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 EAX98165.1 - 0.046 12.7 0.1 0.35 9.8 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAX98165.1 - 0.17 11.5 0.3 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5082 PF16888.5 EAX98166.1 - 0.0054 17.0 11.3 0.0054 17.0 11.3 4.4 1 1 2 4 4 3 2 Domain of unknown function (DUF5082) YvfG PF09628.10 EAX98166.1 - 0.0085 16.4 4.2 0.41 11.0 0.1 3.3 2 1 1 3 3 3 1 YvfG protein DUF848 PF05852.11 EAX98166.1 - 0.01 16.0 7.6 0.01 16.0 7.6 3.7 2 2 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_DNA_bd PF12329.8 EAX98166.1 - 0.017 15.1 3.0 0.017 15.1 3.0 6.3 2 2 2 5 5 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EAX98166.1 - 0.04 13.7 0.9 0.04 13.7 0.9 6.6 4 2 3 7 7 7 0 Septum formation initiator Med9 PF07544.13 EAX98166.1 - 0.047 13.8 1.4 0.047 13.8 1.4 5.7 3 2 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 EAX98166.1 - 0.47 9.3 53.8 0.26 10.1 15.7 3.6 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EAX98166.1 - 1.5 8.9 28.3 4.5 7.3 9.8 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EAX98166.1 - 3.2 7.0 27.3 0.83 9.0 12.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 EAX98166.1 - 3.4 8.6 51.0 1.5 9.7 8.7 5.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2746 PF10874.8 EAX98166.1 - 7.2 7.1 9.3 1.9 9.0 0.2 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF2746) Ank_2 PF12796.7 EAX98167.1 - 2.1e-81 268.6 11.8 9.6e-20 71.0 0.2 4.1 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98167.1 - 1.8e-39 133.6 0.2 4.3e-10 39.9 0.0 5.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98167.1 - 2.8e-35 119.9 2.1 1.1e-07 31.9 0.0 6.3 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98167.1 - 4.9e-32 106.4 0.0 5.7e-05 23.2 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EAX98167.1 - 3e-31 106.5 0.7 3.9e-07 30.2 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat DUF5082 PF16888.5 EAX98167.1 - 0.017 15.4 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF2807 PF10988.8 EAX98168.1 - 0.054 13.3 1.0 0.087 12.6 0.7 1.5 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF5640 PF18692.1 EAX98168.1 - 0.06 13.4 1.9 0.093 12.8 0.8 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5640) YqbF PF14553.6 EAX98168.1 - 0.4 10.6 3.0 1.3 8.9 1.0 2.6 2 1 0 2 2 2 0 YqbF, hypothetical protein domain DUF4108 PF13390.6 EAX98170.1 - 1.2e-62 210.0 5.8 1.4e-62 209.9 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX98170.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX98172.1 - 2e-06 27.5 2.2 2.7e-06 27.0 2.2 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX98172.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4588 PF15251.6 EAX98172.1 - 0.083 12.6 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX98172.1 - 0.18 11.8 2.2 1.3 9.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX98172.1 - 0.68 10.1 8.6 6.9 6.9 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX98173.1 - 1.9e-152 505.6 13.0 2.3e-152 505.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAX98173.1 - 0.2 12.0 0.8 0.58 10.5 0.1 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX98173.1 - 1.5 9.4 4.1 1.3 9.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TMP PF05017.14 EAX98175.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX98176.1 - 0.087 12.7 1.2 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 PSP Ank_4 PF13637.6 EAX98177.1 - 7.2e-18 64.7 0.8 8e-09 35.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98177.1 - 2.9e-16 59.8 2.6 1.3e-09 38.5 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98177.1 - 5.4e-12 45.7 0.6 3.5e-08 33.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98177.1 - 8e-11 41.9 2.0 0.042 14.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX98177.1 - 8.9e-11 41.1 2.0 0.035 14.6 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ras PF00071.22 EAX98179.1 - 8.8e-64 214.0 0.3 1e-63 213.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX98179.1 - 2e-34 118.4 0.1 3.3e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX98179.1 - 5.6e-16 58.5 0.1 7e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX98179.1 - 1.1e-06 28.1 0.1 1.3e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX98179.1 - 0.00043 20.4 0.1 0.00078 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX98179.1 - 0.0006 19.4 0.4 0.0022 17.5 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAX98179.1 - 0.0012 18.8 0.2 1.3 8.9 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_7 PF12775.7 EAX98179.1 - 0.0052 16.3 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region SRPRB PF09439.10 EAX98179.1 - 0.0061 16.0 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAX98179.1 - 0.0087 15.8 0.1 0.027 14.2 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EAX98179.1 - 0.016 15.4 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAX98179.1 - 0.018 15.4 0.0 0.11 12.9 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX98179.1 - 0.023 15.1 0.0 0.027 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 EAX98179.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 EAX98179.1 - 0.028 14.2 0.1 0.067 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EAX98179.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAX98179.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAX98179.1 - 0.088 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) YjbF PF11102.8 EAX98180.1 - 0.049 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Bromodomain PF00439.25 EAX98181.1 - 2.2e-21 75.7 0.3 2.9e-21 75.3 0.3 1.2 1 0 0 1 1 1 1 Bromodomain Pro_isomerase PF00160.21 EAX98182.1 - 1.1e-41 142.8 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zinc_ribbon_16 PF17034.5 EAX98183.1 - 0.049 13.8 0.3 9.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon like family DUF4407 PF14362.6 EAX98183.1 - 0.51 9.6 13.4 0.77 9.1 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 EAX98183.1 - 5.8 6.6 32.5 0.57 9.9 0.2 3.5 2 1 0 4 4 4 0 SWI5-dependent HO expression protein 3 Ank_2 PF12796.7 EAX98184.1 - 7.8e-126 411.0 53.5 2.3e-17 63.3 1.0 7.9 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98184.1 - 4.1e-99 323.8 14.4 2.5e-14 53.4 0.1 11.1 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX98184.1 - 2.9e-84 274.1 1.9 6.5e-08 32.7 0.0 11.3 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 EAX98184.1 - 2.7e-76 242.3 14.0 8.8e-07 28.8 0.0 12.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAX98184.1 - 8.2e-60 198.1 8.6 5.5e-11 42.5 0.0 7.9 3 2 3 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98184.1 - 1.4e-34 117.9 4.9 1.4e-34 117.9 4.9 5.6 2 1 1 5 5 5 1 Domain of unknown function (DUF3447) DUF3124 PF11322.8 EAX98184.1 - 1.4e-05 25.3 0.4 5.5 7.2 0.0 5.1 1 1 4 6 6 6 1 Protein of unknown function (DUF3124) RL PF17797.1 EAX98184.1 - 0.00041 20.2 24.8 1.5 8.8 0.2 7.8 5 2 4 9 9 9 4 RL domain SNase PF00565.17 EAX98184.1 - 0.0034 17.9 11.8 9.2 6.8 5.3 4.7 1 1 2 3 3 3 1 Staphylococcal nuclease homologue ATP13 PF12921.7 EAX98184.1 - 0.02 14.7 0.7 0.17 11.7 0.7 2.8 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF1293 PF06950.11 EAX98184.1 - 0.084 13.0 0.0 24 5.1 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1293) Endonuc-dimeris PF09124.10 EAX98184.1 - 0.23 11.7 10.7 26 5.1 0.0 7.6 7 1 2 9 9 9 0 T4 recombination endonuclease VII, dimerisation Ribosomal_S3_C PF00189.20 EAX98187.1 - 1.6e-19 70.2 2.0 3.8e-19 69.0 1.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EAX98187.1 - 6.8e-06 25.8 0.3 1.3e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 KH domain SHIPPO-rpt PF07004.12 EAX98188.1 - 0.016 16.1 57.1 0.2 12.7 3.1 8.7 8 2 0 8 8 8 0 Sperm-tail PG-rich repeat LRR_5 PF13306.6 EAX98191.1 - 8.5e-15 54.9 14.8 1.2e-14 54.4 14.8 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EAX98191.1 - 0.17 12.1 3.8 5.1 7.4 0.4 2.4 2 0 0 2 2 2 0 FNIP Repeat Gly_rich PF12810.7 EAX98192.1 - 6.8e-55 186.6 47.3 8.4e-55 186.3 47.3 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF1192 PF06698.11 EAX98193.1 - 0.0034 17.4 2.2 0.0034 17.4 2.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) GIT_CC PF16559.5 EAX98193.1 - 0.017 15.0 2.1 0.017 15.0 2.1 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 EAX98193.1 - 0.026 14.6 7.1 0.026 14.6 7.1 2.4 1 1 0 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 EAX98193.1 - 0.054 13.4 1.3 0.17 11.8 1.3 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phlebovirus_NSM PF07246.11 EAX98193.1 - 1.4 8.3 13.0 3.1 7.1 13.0 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tropomyosin_1 PF12718.7 EAX98193.1 - 1.8 8.7 21.4 0.098 12.8 8.9 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF1930 PF09122.10 EAX98194.1 - 0.74 9.8 4.7 22 5.1 0.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1930) DNA_pol_B_2 PF03175.13 EAX98197.1 - 2.3e-18 66.3 5.2 3.1e-17 62.6 5.2 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PapD_N PF00345.20 EAX98198.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX98198.1 - 0.044 13.8 0.5 0.066 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX98199.1 - 0.016 15.6 0.4 0.023 15.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAX98199.1 - 2.7 8.7 6.3 6.1 7.5 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Trypan_PARP PF05887.11 EAX98200.1 - 0.022 14.7 10.1 0.031 14.2 10.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBFD_NFYB_HMF PF00808.23 EAX98203.1 - 0.035 14.4 0.4 0.12 12.6 0.4 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EpsG PF14897.6 EAX98205.1 - 0.019 14.3 1.3 0.036 13.4 1.3 1.4 1 0 0 1 1 1 0 EpsG family Snapin_Pallidin PF14712.6 EAX98207.1 - 0.0024 18.2 4.0 0.019 15.4 0.6 3.0 1 1 0 2 2 2 1 Snapin/Pallidin NPV_P10 PF05531.12 EAX98207.1 - 0.1 13.1 7.4 0.1 13.1 3.6 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EAX98207.1 - 0.56 10.6 6.2 1 9.8 1.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 EAX98207.1 - 0.68 9.7 14.4 0.17 11.7 9.2 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 EAX98207.1 - 0.97 9.7 10.8 0.29 11.4 4.5 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain BST2 PF16716.5 EAX98207.1 - 2.3 8.8 7.8 0.94 10.1 2.6 2.6 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 EAX98207.1 - 2.6 7.2 6.0 0.18 11.0 1.3 1.5 2 0 0 2 2 2 0 TMPIT-like protein tRNA-synt_1b PF00579.25 EAX98208.1 - 3.4e-52 177.6 0.1 4.3e-52 177.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Miga PF10265.9 EAX98209.1 - 0.0044 16.1 1.1 0.006 15.6 1.1 1.1 1 0 0 1 1 1 1 Mitoguardin Shisa PF13908.6 EAX98209.1 - 0.0052 17.1 0.2 0.0081 16.4 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1689 PF07954.11 EAX98209.1 - 0.012 16.0 0.1 0.023 15.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Cadherin_C_2 PF16492.5 EAX98209.1 - 0.034 14.9 0.1 0.08 13.7 0.1 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Phage_holin_2_3 PF16080.5 EAX98209.1 - 0.043 13.6 0.2 0.043 13.6 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Epiglycanin_C PF14654.6 EAX98209.1 - 0.16 12.1 0.2 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region EphA2_TM PF14575.6 EAX98209.1 - 0.17 12.8 0.2 0.47 11.4 0.1 1.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5383 PF17355.2 EAX98209.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5383) Mu-transpos_C PF09299.11 EAX98210.1 - 2.5 8.1 4.4 4.9 7.2 0.5 2.9 3 0 0 3 3 3 0 Mu transposase, C-terminal DUF2353 PF09789.9 EAX98211.1 - 0.0019 17.6 25.8 0.0019 17.6 25.8 7.4 3 3 3 7 7 7 1 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 EAX98211.1 - 0.0047 15.8 18.6 0.0047 15.8 18.6 8.3 4 2 4 8 8 8 5 Spc7 kinetochore protein ZapB PF06005.12 EAX98211.1 - 0.013 15.9 10.0 0.013 15.9 10.0 14.9 7 4 5 12 12 12 0 Cell division protein ZapB YdaT_toxin PF06254.11 EAX98211.1 - 0.94 10.1 5.2 0.57 10.8 1.3 2.8 2 1 0 2 2 2 0 Putative bacterial toxin ydaT Peptidase_S28 PF05577.12 EAX98212.1 - 3.6e-45 154.6 0.2 8.3e-45 153.4 0.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF3267 PF11667.8 EAX98212.1 - 0.1 12.9 0.3 0.28 11.5 0.3 1.6 1 0 0 1 1 1 0 Putative zincin peptidase Gly_rich PF12810.7 EAX98213.1 - 1e-50 172.9 27.1 1.2e-50 172.7 27.1 1.0 1 0 0 1 1 1 1 Glycine rich protein FAM76 PF16046.5 EAX98214.1 - 0.0093 15.4 11.4 0.01 15.2 11.4 1.2 1 0 0 1 1 1 1 FAM76 protein ATG16 PF08614.11 EAX98214.1 - 0.024 14.9 8.6 0.035 14.3 8.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EAX98214.1 - 0.026 14.4 12.4 0.038 13.8 12.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 EAX98214.1 - 0.1 11.9 3.7 0.14 11.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 EAX98214.1 - 0.11 12.3 10.5 0.11 12.4 5.0 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MnmE_helical PF12631.7 EAX98214.1 - 0.12 12.5 3.0 0.18 11.9 3.0 1.3 1 0 0 1 1 1 0 MnmE helical domain DASH_Dad3 PF08656.10 EAX98214.1 - 0.29 11.2 5.4 0.087 12.9 1.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 Fib_alpha PF08702.10 EAX98214.1 - 1.9 8.7 10.5 0.78 9.9 7.1 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EAX98214.1 - 3.8 8.2 8.4 3 8.5 4.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA HAD_2 PF13419.6 EAX98215.1 - 2.6e-06 27.6 0.0 3.9e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX98215.1 - 2.8e-06 27.3 0.0 5.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAX98215.1 - 3.1e-05 24.4 0.0 3.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAX98215.1 - 0.025 15.0 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EAX98216.1 - 6.5e-65 219.1 0.3 8.3e-65 218.8 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98216.1 - 1.3e-41 142.6 0.1 1.5e-41 142.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98216.1 - 2.9e-08 33.4 0.1 2e-07 30.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX98216.1 - 4.2e-06 25.8 0.7 9.4e-06 24.6 0.3 1.7 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EAX98216.1 - 0.00015 20.8 0.5 0.00024 20.2 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX98216.1 - 0.00029 20.2 0.3 0.0007 19.0 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX98216.1 - 0.0021 17.7 0.5 0.0037 16.9 0.5 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAX98216.1 - 0.0028 17.6 0.2 0.0061 16.5 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAX98216.1 - 0.0062 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EAX98216.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EAX98216.1 - 0.087 12.4 0.6 0.29 10.7 0.2 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 EAX98216.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Takusan PF04822.13 EAX98217.1 - 0.034 14.0 0.1 0.47 10.4 0.0 2.2 2 1 0 2 2 2 0 Takusan Phage_GPO PF05929.11 EAX98217.1 - 0.04 13.5 1.2 0.045 13.4 1.2 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_18 PF13238.6 EAX98218.1 - 0.028 15.0 0.6 0.32 11.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain Suv3_N PF18114.1 EAX98218.1 - 0.038 14.1 0.8 0.038 14.1 0.8 2.1 3 0 0 3 3 3 0 Suv3 helical N-terminal domain LRR_5 PF13306.6 EAX98219.1 - 7.2e-49 165.0 27.1 8.8e-30 103.3 13.5 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98219.1 - 5e-08 32.6 0.1 0.012 15.4 0.0 4.3 1 1 3 4 4 4 3 Leucine rich repeat DUF2179 PF10035.9 EAX98219.1 - 0.13 12.0 0.7 4.9 7.0 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) Connexin PF00029.19 EAX98220.1 - 0.0018 18.1 4.3 0.0022 17.8 4.3 1.0 1 0 0 1 1 1 1 Connexin DUF2151 PF10221.9 EAX98220.1 - 0.012 14.2 8.5 0.014 14.1 8.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Pns11_12 PF17464.2 EAX98220.1 - 0.019 14.7 8.6 0.022 14.5 8.6 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 DUF2340 PF10209.9 EAX98220.1 - 0.022 15.2 4.3 0.029 14.8 4.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) RPN2_C PF18004.1 EAX98220.1 - 0.14 12.1 14.0 0.16 11.9 14.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain LETM1 PF07766.13 EAX98220.1 - 0.27 10.5 6.6 0.37 10.1 6.6 1.1 1 0 0 1 1 1 0 LETM1-like protein Presenilin PF01080.17 EAX98220.1 - 0.73 8.5 6.4 0.81 8.4 6.4 1.0 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 EAX98220.1 - 0.8 8.7 3.4 0.9 8.5 3.4 1.0 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 EAX98220.1 - 1.8 8.4 3.4 2.2 8.2 3.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein V_ATPase_I PF01496.19 EAX98220.1 - 2 6.2 8.0 2.3 6.0 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 EAX98220.1 - 2.2 7.8 10.4 2.7 7.5 10.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 EAX98220.1 - 5.4 5.9 5.8 6 5.8 5.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 EAX98220.1 - 6 6.0 5.1 6.7 5.8 5.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Thioredoxin PF00085.20 EAX98221.1 - 8.3e-06 25.7 0.0 0.018 15.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin TrbC_Ftype PF09673.10 EAX98221.1 - 0.053 13.6 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.6 EAX98221.1 - 0.12 12.8 0.2 4.7 7.7 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like domain Xpo1 PF08389.12 EAX98222.1 - 0.054 13.6 1.6 0.33 11.0 0.1 2.1 1 1 1 2 2 2 0 Exportin 1-like protein Flavodoxin_2 PF02525.17 EAX98223.1 - 2.2e-33 115.7 0.1 2.6e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAX98223.1 - 0.0087 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase RGS PF00615.19 EAX98224.1 - 6.7e-22 78.0 0.5 9.8e-22 77.4 0.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 EAX98224.1 - 0.022 14.5 0.2 0.034 13.9 0.2 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DHHC PF01529.20 EAX98224.1 - 0.4 10.8 10.5 2.2 8.4 10.6 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase Ank_2 PF12796.7 EAX98225.1 - 9.1e-39 131.9 14.8 3.7e-12 46.7 0.3 5.9 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98225.1 - 5.2e-35 119.4 12.7 4.7e-07 30.2 0.0 8.6 1 1 9 10 10 10 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98225.1 - 1.4e-34 117.8 6.7 1.4e-34 117.8 6.7 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX98225.1 - 8.2e-34 114.6 9.9 6.3e-08 32.7 0.3 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EAX98225.1 - 5.1e-31 103.2 15.3 4.7e-05 23.5 0.2 9.6 9 1 1 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX98225.1 - 1e-25 89.4 11.7 1.3e-07 31.7 0.0 7.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX98226.1 - 4.9e-51 170.5 14.6 1.3e-11 44.8 0.1 8.1 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98226.1 - 1.3e-41 141.1 13.9 8.7e-16 58.3 0.4 5.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98226.1 - 2.6e-38 125.6 11.9 3.1e-05 24.0 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAX98226.1 - 1.1e-36 124.4 8.0 3.4e-10 40.0 0.1 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX98226.1 - 2.5e-35 119.4 8.4 5.2e-07 29.8 0.1 8.2 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 EAX98226.1 - 4e-31 106.8 22.1 4.9e-30 103.3 1.7 4.8 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) DUF3124 PF11322.8 EAX98226.1 - 0.067 13.4 0.1 5 7.4 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3124) DUF3718 PF12514.8 EAX98226.1 - 0.62 10.3 3.2 46 4.3 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3718) Cactin_mid PF10312.9 EAX98227.1 - 0.0023 17.7 0.2 0.0035 17.1 0.2 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin EpsG PF14897.6 EAX98227.1 - 0.035 13.4 3.3 0.045 13.1 3.3 1.1 1 0 0 1 1 1 0 EpsG family Mcm10 PF09332.11 EAX98227.1 - 0.12 11.8 6.2 0.17 11.3 6.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF4131 PF13567.6 EAX98228.1 - 2 8.0 6.7 0.41 10.3 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 EAX98228.1 - 3.3 6.4 4.6 2.6 6.7 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1282 PF06930.12 EAX98228.1 - 4 7.2 11.8 0.76 9.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Metallophos PF00149.28 EAX98229.1 - 6.7e-28 98.6 0.3 8.9e-28 98.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_16 PF13191.6 EAX98231.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EAX98231.1 - 0.00031 20.7 0.0 0.00084 19.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAX98231.1 - 0.0015 18.1 0.2 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAX98231.1 - 0.016 15.4 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX98231.1 - 0.035 13.2 0.3 0.056 12.5 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EAX98231.1 - 0.051 14.0 0.1 0.23 11.9 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EAX98231.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein FANCI_HD1 PF14679.6 EAX98231.1 - 0.089 12.8 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 FANCI helical domain 1 DUF1664 PF07889.12 EAX98233.1 - 0.0074 16.3 0.4 0.015 15.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MCPsignal PF00015.21 EAX98233.1 - 0.04 13.7 0.6 0.081 12.7 0.6 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 EAX98233.1 - 0.045 13.8 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 EAX98233.1 - 0.054 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 EAX98233.1 - 0.055 13.9 1.5 0.16 12.4 1.5 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cauli_DNA-bind PF03310.13 EAX98233.1 - 0.071 13.2 1.8 0.93 9.6 0.6 2.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Prefoldin_2 PF01920.20 EAX98233.1 - 0.081 12.9 0.7 0.16 11.9 0.7 1.5 1 0 0 1 1 1 0 Prefoldin subunit Nsp1_C PF05064.13 EAX98233.1 - 0.086 12.7 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 Nsp1-like C-terminal region YabA PF06156.13 EAX98233.1 - 0.94 10.1 2.6 0.61 10.7 0.5 1.8 2 0 0 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 EAX98233.1 - 9 6.1 15.6 0.35 10.7 5.4 2.2 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Tyr_Deacylase PF02580.16 EAX98234.1 - 9.9e-51 172.0 0.0 1.1e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF3447 PF11929.8 EAX98235.1 - 1.2e-37 127.7 3.7 1.2e-37 127.7 3.7 2.9 1 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98235.1 - 0.0042 17.6 0.4 0.53 10.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAX98236.1 - 1.7e-26 92.6 17.2 5.5e-13 49.3 3.4 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98236.1 - 1.8e-22 79.4 0.6 1.1e-11 44.9 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98236.1 - 4.2e-17 61.7 2.7 3.4e-05 24.1 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX98236.1 - 3e-13 48.7 0.6 0.005 17.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX98236.1 - 9.5e-12 44.9 0.4 3.9e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CDP-OH_P_transf PF01066.21 EAX98237.1 - 5.1e-13 49.6 1.2 5.1e-13 49.6 1.2 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF423 PF04241.15 EAX98237.1 - 0.14 12.3 4.2 0.1 12.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Ank_2 PF12796.7 EAX98238.1 - 3.2e-05 24.4 0.0 7.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98238.1 - 0.0022 18.3 0.1 0.011 16.1 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAX98238.1 - 0.0058 16.9 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98238.1 - 0.0059 17.0 0.1 0.021 15.3 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeat BST2 PF16716.5 EAX98238.1 - 0.011 16.3 4.0 0.13 12.9 2.6 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CCDC24 PF15669.5 EAX98238.1 - 0.02 14.8 0.5 0.032 14.1 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SlyX PF04102.12 EAX98238.1 - 0.022 15.4 2.1 0.045 14.4 2.1 1.5 1 0 0 1 1 1 0 SlyX Vps51 PF08700.11 EAX98238.1 - 0.026 14.6 1.5 0.026 14.6 1.5 2.2 2 1 0 2 2 2 0 Vps51/Vps67 Pro-MCH PF05824.12 EAX98238.1 - 0.032 14.1 1.1 0.12 12.4 0.1 2.1 1 1 1 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) DUF2681 PF10883.8 EAX98238.1 - 0.042 14.2 1.8 0.081 13.3 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DivIC PF04977.15 EAX98238.1 - 0.054 13.3 2.7 0.12 12.1 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 EAX98238.1 - 0.062 13.6 2.0 0.15 12.3 2.0 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4200 PF13863.6 EAX98238.1 - 0.15 12.4 7.0 0.38 11.1 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Swi5 PF07061.11 EAX98238.1 - 0.32 11.1 5.8 0.23 11.6 3.8 1.8 2 0 0 2 2 2 0 Swi5 NPV_P10 PF05531.12 EAX98238.1 - 0.33 11.5 4.1 0.13 12.7 1.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HTH_54 PF18607.1 EAX98238.1 - 0.39 10.8 8.3 0.095 12.8 0.8 2.5 2 1 0 2 2 2 0 ParA helix turn helix domain Allexi_40kDa PF05549.11 EAX98238.1 - 0.5 9.8 5.7 0.37 10.3 4.2 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2203 PF09969.9 EAX98238.1 - 0.98 10.2 4.5 11 6.7 1.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-C4H2 PF10146.9 EAX98238.1 - 2.6 8.3 7.3 2.1 8.6 6.0 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein LRR_8 PF13855.6 EAX98239.1 - 1e-07 31.6 2.0 2.1e-07 30.6 2.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EAX98239.1 - 0.00037 20.8 8.3 0.0022 18.3 6.2 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX98239.1 - 0.088 12.3 0.2 0.26 10.8 0.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 EAX98239.1 - 0.48 10.6 4.1 6.1 7.2 1.1 2.9 2 0 0 2 2 2 0 Leucine Rich repeat ubiquitin PF00240.23 EAX98240.1 - 7e-27 93.0 0.2 1.8e-09 37.2 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EAX98240.1 - 2.6e-08 33.5 2.7 0.0082 15.9 0.1 3.5 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX98240.1 - 6.4e-08 32.9 3.6 0.0021 18.5 0.2 3.8 3 2 1 4 4 4 2 Ubiquitin-like domain DUF3788 PF12663.7 EAX98240.1 - 0.062 13.3 0.3 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) TBK1_ULD PF18396.1 EAX98240.1 - 0.065 13.2 0.0 24 4.9 0.0 3.3 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain DnaJ_C PF01556.18 EAX98241.1 - 1.4e-27 96.6 0.0 2.3e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX98241.1 - 4.3e-18 65.2 3.7 7.1e-18 64.5 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1031 PF06275.11 EAX98241.1 - 0.14 12.4 0.3 0.29 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Peptidase_M2 PF01401.18 EAX98241.1 - 0.36 9.4 1.2 0.51 8.9 1.2 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme CSTF2_hinge PF14327.6 EAX98242.1 - 0.00019 21.8 1.4 0.00019 21.8 1.4 2.6 2 1 1 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 TSC22 PF01166.18 EAX98242.1 - 0.17 12.2 3.4 1.1 9.6 0.3 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family CP12 PF02672.15 EAX98242.1 - 0.65 10.8 4.0 4.1 8.2 0.1 2.5 2 0 0 2 2 2 0 CP12 domain DUF5357 PF17310.2 EAX98242.1 - 0.73 8.3 3.5 0.92 8.0 3.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) TAF6_C PF07571.13 EAX98243.1 - 0.12 12.8 0.6 19 5.6 0.0 3.9 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 EAX98243.1 - 3.3 8.4 8.2 12 6.6 0.1 4.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region DNase_II PF03265.15 EAX98244.1 - 1.1e-84 284.5 0.9 1.3e-84 284.3 0.9 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II HAD_2 PF13419.6 EAX98245.1 - 1.4e-12 48.0 0.0 2.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAX98245.1 - 8.2e-08 32.8 0.2 1.1e-06 29.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAX98245.1 - 5.5e-07 30.2 0.0 9.2e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAX98245.1 - 9.6e-06 25.6 0.1 3.8e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like M16C_assoc PF08367.11 EAX98245.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated HMG_box PF00505.19 EAX98246.1 - 2.2e-20 72.8 1.1 1.3e-19 70.3 0.3 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX98246.1 - 3.3e-11 43.6 1.6 5.5e-11 42.9 0.5 1.9 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 EAX98246.1 - 0.015 15.3 1.9 0.024 14.6 1.4 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Epimerase PF01370.21 EAX98246.1 - 0.058 12.8 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L7Ae PF01248.26 EAX98248.1 - 1.6e-16 59.8 1.7 1.9e-16 59.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EAX98248.1 - 0.13 12.2 0.2 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 PELOTA RNA binding domain TPR_12 PF13424.6 EAX98249.1 - 0.00052 20.3 0.6 0.05 13.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAX98249.1 - 0.02 15.0 3.1 0.54 10.5 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.14 EAX98249.1 - 1.1 7.5 19.5 1.8 6.8 19.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_17 PF04724.13 EAX98250.1 - 1.1e-23 83.9 3.8 1.6e-23 83.4 3.8 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 DUF563 PF04577.14 EAX98251.1 - 3.6e-30 105.7 0.6 6e-30 104.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PSP PF04046.16 EAX98252.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Trypan_PARP PF05887.11 EAX98253.1 - 0.02 14.9 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMP PF05017.14 EAX98253.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX98254.1 - 0.057 13.9 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DHOR PF06537.11 EAX98255.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase DUF3839 PF12943.7 EAX98256.1 - 1.6e-149 496.0 14.6 1.9e-149 495.7 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAX98256.1 - 0.13 12.1 0.9 0.42 10.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase Rx_N PF18052.1 EAX98256.1 - 0.16 12.3 0.8 6.5 7.1 0.0 3.4 4 1 0 4 4 4 0 Rx N-terminal domain DUF2408 PF10303.9 EAX98256.1 - 2.6 8.6 4.9 2.5 8.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX98256.1 - 2.9 8.4 5.9 4.5 7.8 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LRR_5 PF13306.6 EAX98257.1 - 6.1e-63 210.5 65.2 1.2e-18 67.3 4.1 4.6 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98257.1 - 6.6e-10 38.6 2.8 0.29 10.9 1.0 6.9 4 3 4 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 EAX98257.1 - 0.00012 22.4 9.0 7.4 7.2 0.0 6.8 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) DUF4773 PF15998.5 EAX98257.1 - 1.8 9.1 9.4 1.6 9.3 2.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4773) LRR_5 PF13306.6 EAX98258.1 - 1.1e-62 209.6 24.3 1.2e-36 125.5 6.8 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98258.1 - 3.1e-10 39.6 1.6 0.0056 16.4 0.2 4.6 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EAX98258.1 - 0.021 15.2 4.5 1.5 9.3 0.4 4.4 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF3377 PF11857.8 EAX98258.1 - 0.049 13.6 1.2 0.1 12.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ODV-E18 PF10717.9 EAX98258.1 - 0.052 13.4 0.3 0.088 12.7 0.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Flp1_like PF16982.5 EAX98258.1 - 0.079 12.4 6.0 0.19 11.2 6.0 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Baculo_11_kDa PF06143.11 EAX98258.1 - 0.16 11.6 1.5 0.41 10.3 1.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4200 PF13863.6 EAX98259.1 - 3e-20 72.8 21.5 3e-20 72.8 21.5 4.9 4 2 1 5 5 5 1 Domain of unknown function (DUF4200) DUF3108 PF11306.8 EAX98259.1 - 0.093 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) DUF4326 PF14216.6 EAX98259.1 - 1.4 9.7 4.9 17 6.2 3.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4326) DUF563 PF04577.14 EAX98261.1 - 1.7e-12 47.9 0.2 5.3e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) VWA_3 PF13768.6 EAX98262.1 - 1.9e-20 73.4 0.0 3.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EAX98262.1 - 3.8e-20 72.2 0.0 1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EAX98262.1 - 1.9e-15 57.6 0.0 5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAX98262.1 - 2.7e-14 53.7 0.0 6.3e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain CoA_trans PF01144.23 EAX98262.1 - 0.023 14.1 0.0 0.1 12.0 0.1 1.9 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.25 EAX98264.1 - 1e-10 41.4 0.0 3.8e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain IQ PF00612.27 EAX98264.1 - 0.00021 20.8 12.7 0.0054 16.4 0.7 2.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 EAX98264.1 - 0.0023 17.3 0.0 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1512 PF07431.12 EAX98264.1 - 2.6 7.0 4.6 0.71 8.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) Staphostatin_A PF09022.10 EAX98265.1 - 0.018 14.9 3.9 0.023 14.6 0.1 3.0 3 2 1 4 4 4 0 Staphostatin A LRR_5 PF13306.6 EAX98267.1 - 3.5e-74 246.9 50.0 3.5e-22 78.7 3.7 4.8 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98267.1 - 1.3e-12 47.3 5.6 0.023 14.5 0.0 7.1 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EAX98267.1 - 0.0044 17.4 5.3 5.3 7.6 0.1 5.7 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) Peptidase_S8 PF00082.22 EAX98269.1 - 2.4e-35 122.3 0.1 3.6e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 Subtilase family TNFR_16_TM PF18422.1 EAX98269.1 - 0.00033 20.5 0.5 0.00077 19.4 0.5 1.6 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain O-ag_pol_Wzy PF14296.6 EAX98269.1 - 0.012 14.3 0.3 0.02 13.6 0.3 1.3 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4064 PF13273.6 EAX98269.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) P_proprotein PF01483.20 EAX98269.1 - 0.028 14.5 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 Proprotein convertase P-domain zf-RING_5 PF14634.6 EAX98270.1 - 1.7e-05 24.7 7.3 2.6e-05 24.1 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 EAX98270.1 - 0.028 14.5 7.7 0.046 13.8 7.7 1.4 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 EAX98270.1 - 0.048 14.0 7.4 0.077 13.4 7.4 1.3 1 0 0 1 1 1 0 Ring finger domain TerY_C PF15616.6 EAX98270.1 - 0.051 13.7 0.6 0.089 12.9 0.6 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C3HC4_2 PF13923.6 EAX98270.1 - 0.22 11.4 7.8 0.39 10.6 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAX98270.1 - 0.35 11.2 3.7 0.65 10.3 3.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zinc_ribbon_5 PF13719.6 EAX98270.1 - 0.36 10.6 2.3 7.8 6.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_4 PF14447.6 EAX98270.1 - 0.71 9.8 7.5 1.4 8.8 7.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.6 EAX98270.1 - 2 8.2 6.1 11 5.9 0.8 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4 PF00097.25 EAX98270.1 - 3.8 7.4 7.1 8.4 6.4 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.19 EAX98271.1 - 1.3e-138 462.0 0.0 5e-138 460.1 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAX98271.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT PALP PF00291.25 EAX98273.1 - 3e-72 243.5 0.0 3.6e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_Ferredox PF11591.8 EAX98273.1 - 0.19 11.6 2.3 0.45 10.4 2.3 1.6 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide FAM76 PF16046.5 EAX98274.1 - 0.00023 20.6 19.4 0.00023 20.6 19.4 6.0 2 2 2 5 5 5 1 FAM76 protein RuvC PF02075.17 EAX98274.1 - 0.024 14.5 8.5 0.068 13.0 1.4 4.0 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC DUF5601 PF18151.1 EAX98274.1 - 0.8 10.1 16.9 0.26 11.6 4.9 5.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) V-SNARE_C PF12352.8 EAX98274.1 - 2.7 8.3 19.5 6.6 7.1 0.0 5.6 6 0 0 6 6 6 0 Snare region anchored in the vesicle membrane C-terminus LRR_5 PF13306.6 EAX98277.1 - 2.9e-31 108.1 27.7 7.7e-20 71.2 11.6 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98277.1 - 0.052 13.3 0.0 3.9 7.3 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeat KilA-N PF04383.13 EAX98278.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX98278.1 - 0.16 11.4 0.3 0.3 10.5 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX98279.1 - 7.8e-155 513.4 13.7 9.5e-155 513.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX98279.1 - 0.41 11.1 3.5 4.2 7.9 0.0 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3447 PF11929.8 EAX98280.1 - 3.5e-23 81.4 4.4 3.5e-23 81.4 4.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98280.1 - 5.1e-20 71.9 4.0 3.5e-12 46.7 0.4 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98280.1 - 4.4e-14 52.6 1.7 2.4e-07 31.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98280.1 - 2e-13 50.1 0.1 2.4e-05 24.6 0.0 3.5 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX98280.1 - 7.5e-09 35.1 0.3 0.09 13.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAX98280.1 - 4.4e-07 30.1 0.3 2.1e-06 27.9 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF3895 PF13034.6 EAX98280.1 - 0.037 14.0 0.9 8.3 6.5 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3895) RL PF17797.1 EAX98280.1 - 0.15 12.0 5.9 0.9 9.5 0.7 2.7 2 1 1 3 3 3 0 RL domain HSBP1 PF06825.12 EAX98281.1 - 0.023 14.5 2.6 0.089 12.7 0.1 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CdvA PF18822.1 EAX98281.1 - 0.028 14.2 0.4 0.028 14.2 0.4 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain CLZ PF16526.5 EAX98281.1 - 0.45 10.9 0.0 0.45 10.9 0.0 3.1 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 EAX98281.1 - 0.99 8.9 7.6 0.11 12.1 1.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region Snapin_Pallidin PF14712.6 EAX98281.1 - 1.7 9.1 7.6 1 9.8 2.6 2.5 2 1 0 2 2 2 0 Snapin/Pallidin PAP2 PF01569.21 EAX98282.1 - 1.6e-27 95.9 6.1 1.6e-27 95.9 6.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EAX98282.1 - 1.5e-07 31.3 5.5 2.3e-07 30.7 5.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EAX98282.1 - 5.9e-05 23.5 7.3 0.0008 19.9 0.6 2.4 2 0 0 2 2 2 2 PAP2 superfamily C-terminal ATP-synt_I PF03899.15 EAX98282.1 - 0.37 11.2 11.6 0.4 11.1 1.3 3.0 3 1 0 3 3 3 0 ATP synthase I chain LPP PF04728.13 EAX98283.1 - 0.015 15.7 12.1 3.1 8.3 0.4 4.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DpnI_C PF17726.1 EAX98284.1 - 1.8 8.8 12.8 1.5 9.0 6.2 2.3 2 0 0 2 2 2 0 Dam-replacing HTH domain Ank_2 PF12796.7 EAX98285.1 - 0.00038 21.0 0.1 0.0024 18.4 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98285.1 - 0.0007 19.9 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98285.1 - 0.0035 17.7 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EAX98285.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 EAX98286.1 - 4.7e-22 78.4 5.3 4.4e-13 49.6 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98286.1 - 2.6e-15 56.5 0.6 0.00017 22.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98286.1 - 1.9e-13 50.3 1.5 8.4e-07 29.2 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX98286.1 - 6.2e-11 42.2 0.5 6.1e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAX98286.1 - 9.8e-10 37.8 1.2 0.023 15.2 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat FAINT PF04385.15 EAX98287.1 - 0.3 11.2 4.6 0.3 11.2 2.1 2.3 1 1 2 3 3 3 0 Domain of unknown function, DUF529 DUF4249 PF14054.6 EAX98288.1 - 0.0037 17.0 6.0 0.0078 15.9 5.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4249) RMI2 PF16100.5 EAX98290.1 - 4.9e-05 23.2 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 EAX98290.1 - 0.0005 20.0 0.1 0.00095 19.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ig PF00047.25 EAX98290.1 - 0.089 13.0 0.7 0.61 10.3 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin domain NOP19 PF10863.8 EAX98290.1 - 0.13 12.1 0.6 1.7 8.5 0.2 2.0 2 0 0 2 2 2 0 Nucleolar protein 19 RNA_pol_A_CTD PF03118.15 EAX98291.1 - 0.022 14.5 0.8 0.022 14.5 0.8 2.3 2 1 1 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain Spore_III_AB PF09548.10 EAX98291.1 - 0.13 12.4 12.5 1.8 8.6 5.0 3.3 1 1 2 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Baculo_PEP_C PF04513.12 EAX98291.1 - 0.34 10.9 9.5 0.74 9.8 0.7 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.10 EAX98291.1 - 0.52 10.3 7.2 0.062 13.3 2.0 1.9 2 0 0 2 2 2 0 Serine rich protein interaction domain DDHD PF02862.17 EAX98291.1 - 4.5 7.4 8.8 3.1 7.9 0.1 2.3 1 1 1 2 2 2 0 DDHD domain PSP PF04046.16 EAX98292.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98293.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX98294.1 - 0.044 14.3 0.5 0.092 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) T5orf172 PF10544.9 EAX98295.1 - 4.6e-07 30.3 0.3 8.1e-07 29.5 0.3 1.4 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX98296.1 - 3.4e-43 146.1 0.7 7.6e-43 144.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX98296.1 - 0.025 15.2 0.1 0.063 13.9 0.0 1.7 2 0 0 2 2 2 0 Parathyroid hormone family Thymosin PF01290.20 EAX98297.1 - 0.0014 18.3 2.5 36 4.2 0.0 4.7 4 0 0 4 4 4 2 Thymosin beta-4 family DUF5355 PF17306.2 EAX98297.1 - 0.21 10.6 7.3 2.1 7.3 0.5 3.3 1 1 3 4 4 4 0 Family of unknown function (DUF5355) DUF3653 PF12375.8 EAX98297.1 - 0.27 11.4 1.9 52 4.0 0.0 3.6 1 1 3 4 4 4 0 Phage protein SHIPPO-rpt PF07004.12 EAX98297.1 - 1 10.4 13.2 57 4.9 0.1 4.1 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat Pox_A32 PF04665.12 EAX98298.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX98298.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX98298.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX98298.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX98298.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX98298.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX98298.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX98298.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX98298.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX98298.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX98298.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX98298.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX98300.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Paf1 PF03985.13 EAX98301.1 - 0.082 11.9 4.2 0.1 11.6 4.2 1.0 1 0 0 1 1 1 0 Paf1 ubiquitin PF00240.23 EAX98302.1 - 1.4e-16 60.0 0.1 1.5e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX98302.1 - 1.3e-09 37.8 1.1 1.4e-09 37.7 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX98302.1 - 0.093 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EAX98302.1 - 0.35 11.0 2.0 14 5.8 0.4 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Tcp10_C PF07202.13 EAX98303.1 - 4e-21 75.8 0.7 4e-21 75.8 0.7 3.0 1 1 1 3 3 3 1 T-complex protein 10 C-terminus CopK PF11525.8 EAX98303.1 - 0.015 14.9 0.3 3.4 7.4 0.2 3.0 2 0 0 2 2 2 0 Copper resistance protein K ChapFlgA PF13144.6 EAX98303.1 - 0.095 12.8 1.0 2.1 8.4 0.5 2.5 2 0 0 2 2 2 0 Chaperone for flagella basal body P-ring formation Methyltransf_32 PF13679.6 EAX98304.1 - 7.4e-12 45.5 3.7 4.5e-11 43.0 3.7 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAX98304.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain AraC_binding PF02311.19 EAX98305.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DUF667 PF05018.13 EAX98306.1 - 1.7e-83 278.9 0.2 1.9e-83 278.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UL45 PF05473.12 EAX98307.1 - 0.0065 16.1 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like ECSCR PF15820.5 EAX98307.1 - 0.037 13.8 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF1467 PF07330.12 EAX98307.1 - 0.046 13.7 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) IBD PF10416.9 EAX98308.1 - 5.6e-31 107.2 0.0 8.1e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Ax_dynein_light PF10211.9 EAX98309.1 - 4.9e-07 29.9 7.0 3.2e-06 27.2 6.7 2.5 1 1 0 1 1 1 1 Axonemal dynein light chain Prp19 PF08606.11 EAX98309.1 - 0.079 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like FlgN PF05130.12 EAX98309.1 - 0.2 12.2 4.7 0.35 11.4 2.3 2.4 1 1 1 2 2 2 0 FlgN protein Spore_III_AB PF09548.10 EAX98309.1 - 1.2 9.2 5.6 2.3 8.3 1.8 2.9 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Voltage_CLC PF00654.20 EAX98310.1 - 0.061 12.6 1.0 0.071 12.3 1.0 1.0 1 0 0 1 1 1 0 Voltage gated chloride channel UL41A PF17591.2 EAX98310.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A CCDC53 PF10152.9 EAX98312.1 - 7.7e-40 136.8 0.0 1.2e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex DUF1774 PF08611.10 EAX98313.1 - 0.042 14.2 4.9 0.97 9.8 0.2 2.5 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) GPS2_interact PF15784.5 EAX98314.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98314.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX98316.1 - 0.02 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PadR PF03551.14 EAX98317.1 - 0.079 12.9 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family MULE PF10551.9 EAX98318.1 - 0.00048 20.5 3.8 0.0012 19.2 0.5 2.7 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 EAX98318.1 - 0.027 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Pkinase PF00069.25 EAX98319.1 - 1.7e-25 89.9 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98319.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T3RM_EcoP15I_C PF18273.1 EAX98319.1 - 0.0049 17.2 4.1 1.6 9.1 0.0 3.5 1 1 2 3 3 3 2 Type III R-M EcoP15I C-terminal domain DUF4133 PF13571.6 EAX98320.1 - 0.014 15.7 2.4 0.021 15.1 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Popeye PF04831.13 EAX98321.1 - 0.11 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Popeye protein conserved region LRR_5 PF13306.6 EAX98322.1 - 6e-49 165.3 53.7 2e-27 95.6 17.3 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98322.1 - 0.00086 19.0 2.5 7.1 6.5 0.0 5.1 3 2 4 7 7 6 2 Leucine rich repeat DUF1068 PF06364.12 EAX98322.1 - 0.62 9.9 0.0 0.62 9.9 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1068) PQ-loop PF04193.14 EAX98323.1 - 6.6e-10 38.6 11.7 3e-09 36.5 2.5 3.5 4 0 0 4 4 4 2 PQ loop repeat MpPF26 PF07666.11 EAX98323.1 - 0.053 13.6 0.4 0.053 13.6 0.4 2.7 3 0 0 3 3 3 0 M penetrans paralogue family 26 Conotoxin PF02950.17 EAX98323.1 - 0.062 14.3 0.0 0.11 13.5 0.0 1.3 1 0 0 1 1 1 0 Conotoxin Sigma_reg_N PF13800.6 EAX98323.1 - 1.9 8.8 5.7 3.2 8.1 0.0 3.1 3 1 0 3 3 3 0 Sigma factor regulator N-terminal TTL PF03133.15 EAX98324.1 - 3.3e-66 223.4 0.7 2.6e-65 220.5 0.2 2.3 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX98324.1 - 2e-10 40.4 2.9 7.7e-06 25.3 0.0 3.7 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX98324.1 - 1.2e-07 31.3 0.0 0.012 14.9 0.0 2.8 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp Pro-kuma_activ PF09286.11 EAX98324.1 - 0.0023 18.3 0.3 0.076 13.3 0.0 2.7 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain ATP-grasp_3 PF02655.14 EAX98324.1 - 0.0027 17.8 0.1 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 EAX98324.1 - 0.064 12.9 0.0 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Hid1 PF12722.7 EAX98325.1 - 1.6e-06 26.6 5.9 0.01 14.0 3.5 2.3 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein CBM_21 PF03370.13 EAX98325.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Rad60-SLD PF11976.8 EAX98326.1 - 0.036 13.9 3.2 0.94 9.4 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like ThiS PF02597.20 EAX98326.1 - 0.066 13.9 0.0 2.8 8.6 0.0 3.1 3 0 0 3 3 3 0 ThiS family Cullin_Nedd8 PF10557.9 EAX98326.1 - 0.3 11.2 1.9 9.1 6.4 0.1 2.9 3 0 0 3 3 3 0 Cullin protein neddylation domain Gram_pos_anchor PF00746.21 EAX98327.1 - 0.13 12.2 0.6 0.19 11.7 0.6 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Pkinase PF00069.25 EAX98328.1 - 1.8e-45 155.3 0.3 2.4e-45 155.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98328.1 - 4.4e-18 65.5 0.7 7.8e-18 64.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX98328.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX98328.1 - 0.0047 16.6 0.5 0.05 13.2 0.4 2.0 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAX98328.1 - 0.0049 16.5 4.6 0.042 13.5 0.2 2.4 2 1 1 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 EAX98328.1 - 0.03 13.1 0.1 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase FYRC PF05965.14 EAX98329.1 - 7.2e-16 58.1 0.1 6.2e-15 55.1 0.0 2.7 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 EAX98329.1 - 4.3e-10 39.3 0.2 9.7e-10 38.1 0.2 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Chromo PF00385.24 EAX98329.1 - 0.00075 19.4 0.1 0.0033 17.3 0.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GPS2_interact PF15784.5 EAX98331.1 - 0.026 14.9 1.5 0.035 14.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98331.1 - 0.099 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAX98332.1 - 0.14 12.2 6.0 0.22 11.5 6.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX98333.1 - 0.018 15.1 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta AlphaC_N PF08829.10 EAX98333.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF2939 PF11159.8 EAX98334.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX98334.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1043 PF06295.12 EAX98335.1 - 0.069 13.1 0.3 0.099 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pox_A32 PF04665.12 EAX98337.1 - 2.1e-07 30.7 0.6 1.3e-06 28.1 0.0 2.2 1 1 2 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.6 EAX98337.1 - 0.046 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAX98337.1 - 0.057 13.1 0.1 1.3 8.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.18 EAX98337.1 - 0.064 13.1 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Thymidine kinase Amidase02_C PF12123.8 EAX98338.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98339.1 - 3.5e-72 241.8 2.8 4.6e-72 241.5 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) MULE PF10551.9 EAX98341.1 - 1.9e-05 25.0 0.1 3.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain MULE PF10551.9 EAX98343.1 - 2.1e-13 50.5 0.1 4.5e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WASH-7_C PF14746.6 EAX98343.1 - 0.14 11.8 4.9 0.24 11.1 1.3 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX98343.1 - 0.27 11.5 5.7 0.8 10.0 5.7 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX98343.1 - 1.1 9.0 4.4 1.8 8.3 4.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 EAX98344.1 - 1.2e-55 188.8 0.0 1.4e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98344.1 - 7.6e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX98344.1 - 0.00013 21.0 0.1 0.00016 20.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX98344.1 - 0.0011 19.0 0.0 0.0035 17.3 0.0 1.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 EAX98344.1 - 0.0041 17.8 0.6 0.0041 17.8 0.6 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EAX98344.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EAX98344.1 - 0.033 13.5 0.0 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EAX98344.1 - 0.097 11.5 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MutL PF13941.6 EAX98346.1 - 0.15 10.6 0.5 0.21 10.2 0.5 1.2 1 0 0 1 1 1 0 MutL protein DUF4724 PF15852.5 EAX98346.1 - 7.9 7.0 6.7 2.5 8.7 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) LRR_4 PF12799.7 EAX98347.1 - 0.00091 19.6 7.8 0.076 13.5 3.4 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX98347.1 - 0.0017 17.9 0.1 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Glyco_hydro_47 PF01532.20 EAX98348.1 - 1.7e-32 112.9 0.0 2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MULE PF10551.9 EAX98349.1 - 0.0019 18.6 0.0 0.0045 17.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Cytochrom_C_asm PF01578.20 EAX98349.1 - 0.015 15.1 0.7 0.022 14.5 0.7 1.4 1 1 0 1 1 1 0 Cytochrome C assembly protein DUF3447 PF11929.8 EAX98352.1 - 4.5e-09 36.1 0.4 2.2e-08 33.9 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98352.1 - 2.3e-08 34.5 0.0 0.00019 21.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98352.1 - 0.00011 22.4 0.3 0.12 13.0 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX98352.1 - 0.00014 22.0 0.0 0.016 15.5 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX98352.1 - 0.033 14.8 0.0 0.76 10.4 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ribosomal_L10 PF00466.20 EAX98353.1 - 2.1e-20 72.7 0.6 6.2e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EAX98353.1 - 1.5e-19 69.7 0.2 2.6e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EAX98353.1 - 1.2e-09 38.6 13.2 2.2e-09 37.8 13.2 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein EpuA PF11772.8 EAX98355.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF1947 PF09183.10 EAX98355.1 - 0.44 10.9 4.7 2.1 8.7 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) ROKNT PF08067.11 EAX98356.1 - 0.029 14.7 0.4 0.05 13.9 0.4 1.4 1 0 0 1 1 1 0 ROKNT (NUC014) domain DUF4172 PF13776.6 EAX98356.1 - 0.053 13.9 0.3 0.071 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) UCH PF00443.29 EAX98357.1 - 6.8e-35 120.8 13.1 3.4e-35 121.8 6.0 3.7 4 2 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX98357.1 - 7.9e-06 25.7 9.4 7.9e-06 25.7 9.4 4.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rad60-SLD PF11976.8 EAX98357.1 - 0.00021 21.1 10.2 0.00098 18.9 0.2 4.5 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAX98357.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin family SapB_2 PF03489.17 EAX98357.1 - 0.024 14.7 0.8 9.3 6.5 0.0 4.5 3 0 0 3 3 3 0 Saposin-like type B, region 2 RNA_polI_A14 PF08203.11 EAX98358.1 - 1.6 9.5 0.0 1.6 9.5 0.0 7.4 8 3 1 9 9 9 0 Yeast RNA polymerase I subunit RPA14 DUF883 PF05957.13 EAX98358.1 - 2.4 8.8 16.4 1 10.0 0.2 5.7 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF883) CheZ PF04344.13 EAX98360.1 - 0.00025 21.0 1.5 0.00031 20.7 1.5 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ ABC_tran_CTD PF16326.5 EAX98360.1 - 0.0052 17.0 4.1 0.0052 17.0 4.1 2.2 2 0 0 2 2 2 1 ABC transporter C-terminal domain DUF4618 PF15397.6 EAX98360.1 - 0.023 14.1 9.6 0.057 12.8 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 EAX98360.1 - 0.024 14.9 1.4 1.1 9.5 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Com_YlbF PF06133.11 EAX98360.1 - 0.028 15.0 9.3 0.39 11.3 9.2 2.2 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA PCRF PF03462.18 EAX98360.1 - 0.061 13.2 5.3 0.073 12.9 4.6 1.4 1 1 0 1 1 1 0 PCRF domain OmpH PF03938.14 EAX98360.1 - 0.2 12.0 8.1 0.99 9.7 8.1 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 EAX98360.1 - 0.29 10.9 7.0 1.1 9.1 7.0 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 EAX98360.1 - 0.3 11.1 5.7 1.3 9.0 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 EAX98360.1 - 0.41 11.1 10.8 0.5 10.8 10.8 1.1 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 EAX98360.1 - 0.72 8.4 7.0 1 7.9 7.0 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A YvrJ PF12841.7 EAX98360.1 - 0.8 9.3 6.0 26 4.4 0.1 3.8 4 0 0 4 4 4 0 YvrJ protein family PhoU PF01895.19 EAX98360.1 - 1.4 9.4 9.3 0.4 11.2 1.9 2.2 1 1 1 2 2 2 0 PhoU domain DASH_Dam1 PF08653.10 EAX98360.1 - 2.2 8.2 5.7 8.3 6.3 2.7 3.0 2 2 0 2 2 2 0 DASH complex subunit Dam1 TMPIT PF07851.13 EAX98360.1 - 2.2 7.5 4.7 2.6 7.2 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFP_35_N PF07334.13 EAX98360.1 - 3.1 8.0 7.8 1.3 9.1 2.3 2.7 1 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Gly-zipper_Omp PF13488.6 EAX98361.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX98361.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX98361.1 - 1.4 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif UPF0239 PF06783.11 EAX98362.1 - 0.032 14.4 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) GPS2_interact PF15784.5 EAX98363.1 - 0.018 15.5 0.8 0.025 15.0 0.8 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain UCH PF00443.29 EAX98366.1 - 6.8e-16 58.5 0.3 6.8e-16 58.5 0.3 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX98366.1 - 9e-07 28.8 0.1 9e-07 28.8 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SOG2 PF10428.9 EAX98366.1 - 2.1 7.5 20.6 3.6 6.7 20.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EAX98366.1 - 4.1 5.9 15.6 5.6 5.4 15.6 1.2 1 0 0 1 1 1 0 Macoilin family SHIPPO-rpt PF07004.12 EAX98367.1 - 0.01 16.7 0.3 0.01 16.7 0.3 3.8 3 2 0 3 3 3 0 Sperm-tail PG-rich repeat Pox_A32 PF04665.12 EAX98368.1 - 7.8e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX98368.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX98368.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX98368.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 HrpB7 PF09486.10 EAX98369.1 - 0.0017 18.8 3.8 0.0017 18.8 3.8 6.0 4 2 1 6 6 6 1 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 EAX98369.1 - 7.4 6.1 120.2 0.38 10.3 16.0 9.4 4 2 2 7 7 7 0 Intermediate filament protein LRR_5 PF13306.6 EAX98370.1 - 4e-72 240.2 39.5 5.2e-25 87.9 0.5 6.1 2 2 4 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98370.1 - 9.2e-06 25.3 0.5 11 5.9 0.0 5.9 4 2 3 7 7 7 0 Leucine rich repeat OAD_gamma PF04277.13 EAX98370.1 - 2.1e-05 25.0 0.9 5e-05 23.8 0.9 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF4381 PF14316.6 EAX98370.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Rax2 PF12768.7 EAX98370.1 - 0.0015 18.0 0.1 0.0074 15.8 0.0 2.2 2 1 0 2 2 2 1 Cortical protein marker for cell polarity Zip PF02535.22 EAX98370.1 - 0.0016 17.7 0.1 0.0024 17.2 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Tmemb_9 PF05434.11 EAX98370.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 TMEM9 DUF4834 PF16118.5 EAX98370.1 - 0.0021 19.0 1.0 0.0068 17.3 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) MAP17 PF15807.5 EAX98370.1 - 0.0024 18.1 1.8 0.0047 17.2 1.8 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HemX PF04375.14 EAX98370.1 - 0.0027 17.1 8.4 0.004 16.5 8.4 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Neur_chan_memb PF02932.16 EAX98370.1 - 0.0041 17.2 0.0 0.0065 16.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 EAX98370.1 - 0.0089 15.9 1.9 0.016 15.0 1.9 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Amnionless PF14828.6 EAX98370.1 - 0.0095 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless Peptidase_S49_N PF08496.10 EAX98370.1 - 0.013 15.6 1.8 0.025 14.6 1.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 EAX98370.1 - 0.02 14.6 1.0 0.04 13.6 1.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SARAF PF06682.12 EAX98370.1 - 0.021 14.5 1.0 0.037 13.7 0.3 1.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Vpu PF00558.19 EAX98370.1 - 0.022 14.5 0.8 0.051 13.3 0.8 1.6 1 0 0 1 1 1 0 Vpu protein DUF2561 PF10812.8 EAX98370.1 - 0.036 14.1 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) 60KD_IMP PF02096.20 EAX98370.1 - 0.047 13.6 2.0 0.11 12.4 2.0 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Baculo_11_kDa PF06143.11 EAX98370.1 - 0.047 13.3 0.5 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4446 PF14584.6 EAX98370.1 - 0.05 13.6 1.7 0.095 12.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) S1FA PF04689.13 EAX98370.1 - 0.054 13.6 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Herpes_gE PF02480.16 EAX98370.1 - 0.064 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAX98370.1 - 0.078 13.9 0.1 0.19 12.6 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V_ATPase_I PF01496.19 EAX98370.1 - 0.11 10.4 2.1 0.16 9.8 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YebO PF13974.6 EAX98370.1 - 0.14 12.2 3.4 0.37 10.9 3.4 1.7 1 0 0 1 1 1 0 YebO-like protein Shisa PF13908.6 EAX98370.1 - 0.15 12.3 2.0 0.17 12.1 0.5 1.7 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4407 PF14362.6 EAX98370.1 - 0.24 10.7 3.0 0.41 10.0 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4330 PF14221.6 EAX98370.1 - 0.39 10.9 3.1 1.1 9.5 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) PIEZO PF15917.5 EAX98370.1 - 1.3 8.4 6.1 2 7.8 6.1 1.2 1 0 0 1 1 1 0 Piezo FAM176 PF14851.6 EAX98370.1 - 9.1 5.9 6.3 28 4.4 6.3 1.8 1 1 0 1 1 1 0 FAM176 family LRR_5 PF13306.6 EAX98371.1 - 8.3e-30 103.4 25.3 4.4e-16 59.0 7.6 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98371.1 - 2.2e-09 36.9 0.1 0.31 10.9 0.0 4.5 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX98371.1 - 6.2e-07 29.6 1.8 0.22 12.0 1.3 4.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EAX98372.1 - 1.2e-70 237.9 0.1 1.6e-70 237.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98372.1 - 1.5e-44 152.3 0.0 2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX98372.1 - 2.6e-09 36.5 0.3 2.6e-09 36.5 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EAX98372.1 - 3.1e-09 36.6 0.0 5.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAX98372.1 - 7.7e-08 32.2 0.7 2e-07 30.8 0.3 1.7 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EAX98372.1 - 0.00015 21.7 0.0 0.00035 20.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98372.1 - 0.0033 16.3 0.1 0.008 15.0 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAX98372.1 - 0.014 15.0 0.2 0.028 14.0 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase IBD PF10416.9 EAX98372.1 - 0.058 13.4 0.5 0.17 11.9 0.5 1.8 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD AAA_14 PF13173.6 EAX98372.1 - 0.092 12.8 0.4 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 AAA domain Folliculin PF11704.8 EAX98373.1 - 8.5e-06 25.8 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SMC_hinge PF06470.13 EAX98373.1 - 0.17 12.2 0.2 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Aminotran_5 PF00266.19 EAX98375.1 - 3e-16 59.4 0.0 3.7e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_C14 PF00656.22 EAX98376.1 - 0.00036 20.6 0.2 0.0044 17.0 0.1 2.1 1 1 0 2 2 2 1 Caspase domain CIDE-N PF02017.15 EAX98376.1 - 0.027 14.5 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 CIDE-N domain Ank_2 PF12796.7 EAX98377.1 - 2.6e-37 127.3 25.7 7.3e-14 52.1 3.3 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98377.1 - 1.8e-32 110.4 2.7 3.1e-08 33.7 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAX98377.1 - 2.9e-30 104.2 5.5 5.2e-09 36.5 0.0 6.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98377.1 - 3.4e-26 88.4 10.1 6e-06 26.2 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX98377.1 - 1.9e-24 85.4 4.0 8.2e-12 45.1 0.1 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98377.1 - 1.7e-19 69.5 5.7 1.7e-19 69.5 5.7 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EAX98377.1 - 0.085 13.1 1.4 2.7 8.4 0.1 3.3 2 1 2 4 4 4 0 Ribosomal protein S6 LRR_5 PF13306.6 EAX98378.1 - 1.4e-111 367.8 60.5 1.4e-22 80.0 4.4 7.3 2 1 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98378.1 - 1e-24 86.1 9.8 0.0021 17.8 0.0 9.8 9 3 2 11 11 11 7 Leucine rich repeat FNIP PF05725.12 EAX98378.1 - 0.53 10.5 11.6 0.41 10.8 0.4 5.8 6 0 0 6 6 6 0 FNIP Repeat DUF563 PF04577.14 EAX98379.1 - 2.7e-28 99.5 0.8 3.3e-28 99.3 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF563) KRTDAP PF15200.6 EAX98379.1 - 0.035 13.9 0.3 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Keratinocyte differentiation-associated Gly-zipper_Omp PF13488.6 EAX98381.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAX98381.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX98381.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Laminin_G_2 PF02210.24 EAX98382.1 - 0.0057 17.2 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain V-ATPase_H_C PF11698.8 EAX98382.1 - 0.0087 16.2 3.2 0.12 12.5 0.9 3.7 3 1 0 3 3 3 1 V-ATPase subunit H RRM_1 PF00076.22 EAX98383.1 - 8.7e-52 172.8 6.9 9.9e-15 54.1 0.2 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX98383.1 - 1.9e-05 24.7 0.6 0.62 10.2 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EAX98383.1 - 0.00014 21.8 0.9 13 5.9 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX98383.1 - 0.00046 20.2 3.3 0.98 9.5 0.3 3.9 4 1 0 4 4 4 2 RNA binding motif DUF3587 PF12132.8 EAX98383.1 - 0.069 12.6 0.7 0.16 11.4 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3587) RRM_occluded PF16842.5 EAX98383.1 - 0.14 12.0 0.0 8 6.4 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif Amidase02_C PF12123.8 EAX98386.1 - 0.0062 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98387.1 - 3.3e-73 245.2 4.8 4e-73 244.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX98387.1 - 0.13 10.6 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase cNMP_binding PF00027.29 EAX98390.1 - 3.8e-40 135.9 0.0 1.3e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EAX98390.1 - 0.038 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DivIC PF04977.15 EAX98391.1 - 0.0029 17.3 3.7 1.3 8.8 0.3 2.8 2 0 0 2 2 2 2 Septum formation initiator YgaB PF14182.6 EAX98391.1 - 0.033 14.6 8.5 12 6.3 1.9 3.8 3 0 0 3 3 3 0 YgaB-like protein TSC22 PF01166.18 EAX98391.1 - 0.034 14.4 1.1 0.12 12.8 1.1 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EAX98391.1 - 0.053 13.6 4.8 0.1 12.6 2.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 EAX98391.1 - 0.38 10.1 16.3 1.3 8.3 16.3 1.9 1 1 0 1 1 1 0 Rabaptin-like protein MbeD_MobD PF04899.12 EAX98391.1 - 0.97 9.6 4.6 0.26 11.4 0.4 2.2 3 0 0 3 3 3 0 MbeD/MobD like NUC PF18510.1 EAX98391.1 - 2.3 8.6 16.4 0.9 10.0 3.0 3.0 1 1 2 3 3 3 0 Nuclease domain TMF_TATA_bd PF12325.8 EAX98391.1 - 3.1 8.0 10.1 6.6 7.0 0.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Pyr_redox_2 PF07992.14 EAX98392.1 - 8.8e-48 163.0 2.5 1.1e-47 162.7 2.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAX98392.1 - 1.6e-19 70.3 1.4 1.6e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAX98392.1 - 2e-16 60.3 6.5 3.2e-15 56.5 1.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAX98392.1 - 1.3e-07 31.3 5.1 7.4e-07 28.9 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EAX98392.1 - 7.6e-07 28.5 7.5 0.0009 18.4 0.7 3.7 2 2 2 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EAX98392.1 - 5.4e-06 26.5 1.2 2.1e-05 24.7 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAX98392.1 - 1.2e-05 24.6 10.0 4.8e-05 22.6 0.8 3.9 3 1 2 5 5 5 1 FAD binding domain Thi4 PF01946.17 EAX98392.1 - 1.3e-05 24.6 8.3 0.00016 21.0 0.1 3.2 2 1 1 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 EAX98392.1 - 0.0001 22.7 0.3 0.056 13.9 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 EAX98392.1 - 0.00013 20.9 4.6 0.066 11.9 0.5 3.7 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 EAX98392.1 - 0.00025 20.4 1.4 0.039 13.2 0.5 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAX98392.1 - 0.00036 20.2 14.3 0.0041 16.8 1.2 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAX98392.1 - 0.0004 19.6 0.4 0.0059 15.8 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EAX98392.1 - 0.099 11.5 0.8 4.6 6.0 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EAX98392.1 - 0.11 11.6 3.2 12 4.8 0.1 3.7 4 0 0 4 4 4 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EAX98392.1 - 0.56 9.5 4.7 4.4 6.6 1.0 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF563 PF04577.14 EAX98393.1 - 2.4e-31 109.5 0.1 2.9e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) VPS9 PF02204.18 EAX98394.1 - 0.0061 16.8 0.8 0.057 13.6 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CREPT PF16566.5 EAX98394.1 - 0.039 14.1 2.4 0.24 11.6 0.1 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Rsbr_N PF08678.10 EAX98394.1 - 0.095 12.8 2.0 0.22 11.6 2.0 1.6 1 0 0 1 1 1 0 Rsbr N terminal DUF16 PF01519.16 EAX98394.1 - 0.67 10.5 7.9 12 6.5 7.8 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 P4Ha_N PF08336.11 EAX98394.1 - 0.88 9.6 4.0 1 9.4 0.9 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pkinase PF00069.25 EAX98395.1 - 1.1e-60 205.2 0.0 1.8e-60 204.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98395.1 - 7.6e-37 127.0 0.0 9.2e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98395.1 - 2e-08 33.9 0.0 2.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EAX98395.1 - 1.4e-05 24.8 0.8 0.0032 17.1 0.1 2.3 1 1 1 2 2 2 2 RIO1 family APH PF01636.23 EAX98395.1 - 1.8e-05 24.8 0.1 0.00018 21.5 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98395.1 - 5.8e-05 22.1 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX98395.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAX98395.1 - 0.0074 15.9 0.3 0.17 11.5 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAX98395.1 - 0.047 12.6 0.1 0.083 11.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF1938 PF09153.10 EAX98395.1 - 0.056 13.5 0.3 0.24 11.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) Pkinase PF00069.25 EAX98396.1 - 9.6e-62 208.7 0.0 2e-61 207.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98396.1 - 2.1e-34 119.0 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98396.1 - 2.8e-06 26.9 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAX98396.1 - 1.7e-05 24.9 0.3 3.8e-05 23.7 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAX98396.1 - 0.00025 20.5 0.2 0.00049 19.5 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX98396.1 - 0.001 17.9 0.3 0.0019 17.1 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EAX98396.1 - 0.019 13.9 0.1 0.032 13.2 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAX98396.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EAX98396.1 - 0.033 13.8 0.2 0.062 12.9 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EAX98396.1 - 0.054 13.1 0.6 0.16 11.6 0.0 2.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Ribonuc_red_sm PF00268.21 EAX98396.1 - 0.084 12.3 0.2 0.34 10.3 0.1 1.9 1 1 1 2 2 2 0 Ribonucleotide reductase, small chain Orf78 PF06024.12 EAX98397.1 - 0.00037 20.7 0.3 0.00048 20.4 0.3 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DUF4083 PF13314.6 EAX98397.1 - 0.002 18.0 1.3 0.0038 17.1 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF4711 PF15829.5 EAX98397.1 - 0.003 17.5 1.8 0.0046 16.9 1.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4711) RIFIN PF02009.16 EAX98397.1 - 0.0072 16.3 0.5 0.0091 15.9 0.5 1.1 1 0 0 1 1 1 1 Rifin YajC PF02699.15 EAX98397.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit m04gp34like PF12216.8 EAX98397.1 - 0.028 14.0 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein Stevor PF17410.2 EAX98397.1 - 0.033 13.7 0.2 0.038 13.5 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Chordopox_G3 PF06129.12 EAX98397.1 - 0.05 14.3 0.3 0.11 13.2 0.1 1.7 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Neurensin PF14927.6 EAX98397.1 - 0.061 13.0 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Neurensin Syndecan PF01034.20 EAX98397.1 - 0.067 13.1 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain FixQ PF05545.11 EAX98397.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.6 EAX98397.1 - 0.13 13.1 0.4 0.33 11.9 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5527 PF17665.1 EAX98397.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF5385 PF17359.2 EAX98397.1 - 0.24 10.9 2.2 0.15 11.6 0.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Mid2 PF04478.12 EAX98397.1 - 0.68 9.8 4.9 1.4 8.7 4.2 1.9 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF4458 PF14660.6 EAX98398.1 - 0.27 11.5 3.3 1.8 8.8 3.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4458) S-l_SbsC_C PF18316.1 EAX98398.1 - 0.6 10.6 5.1 12 6.5 0.5 2.8 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain Corona_S2 PF01601.16 EAX98399.1 - 1.5 7.2 14.7 2.2 6.7 14.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4704 PF15787.5 EAX98400.1 - 3.7e-21 75.6 6.8 3.7e-21 75.6 6.8 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 EAX98400.1 - 5.5e-05 23.4 0.0 9.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Katanin_con80 PF13925.6 EAX98400.1 - 0.052 13.6 3.4 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 con80 domain of Katanin Beach PF02138.18 EAX98401.1 - 5e-105 350.8 1.8 1.1e-104 349.6 1.8 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX98401.1 - 3.9e-05 23.7 6.3 0.00017 21.6 0.7 3.2 2 1 1 3 3 3 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 EAX98401.1 - 8.8e-05 21.9 0.5 0.00021 20.6 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Myb_DNA-bind_4 PF13837.6 EAX98401.1 - 1 9.8 5.2 2 8.9 2.2 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Thiolase_C PF02803.18 EAX98402.1 - 0.033 13.8 0.0 6.1 6.5 0.0 3.0 1 1 2 3 3 3 0 Thiolase, C-terminal domain mRNA_stabil PF13929.6 EAX98402.1 - 0.11 11.5 0.4 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 mRNA stabilisation DUF3447 PF11929.8 EAX98403.1 - 2.8e-40 136.1 7.1 2.8e-40 136.1 7.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98403.1 - 1.6e-34 118.3 24.7 1.5e-12 47.9 3.4 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98403.1 - 4.6e-29 100.4 12.1 2.7e-10 40.6 0.5 6.5 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX98403.1 - 8.9e-27 92.3 6.8 5e-06 26.7 0.2 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX98403.1 - 8.3e-25 84.2 11.1 0.0002 21.5 0.1 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX98403.1 - 1.6e-17 63.3 14.8 7.7e-07 29.3 1.1 6.2 4 1 3 7 7 7 4 Ankyrin repeats (many copies) PI3_PI4_kinase PF00454.27 EAX98404.1 - 2.6e-51 174.9 2.9 6.2e-51 173.6 0.2 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EAX98404.1 - 1.5e-13 51.0 3.7 1.6e-13 50.9 0.9 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EAX98404.1 - 3.2e-13 49.3 0.1 8.8e-13 47.8 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 EAX98404.1 - 1.5e-06 28.6 1.8 0.1 13.1 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3385 PF11865.8 EAX98404.1 - 0.0036 17.2 0.5 0.0036 17.2 0.5 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) MGDG_synth PF06925.11 EAX98404.1 - 0.043 13.9 0.7 0.39 10.8 0.0 2.9 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF1163 PF06651.11 EAX98404.1 - 0.066 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1163) YuiB PF14068.6 EAX98404.1 - 0.097 13.3 0.6 0.49 11.0 0.6 2.3 1 0 0 1 1 1 0 Putative membrane protein RuvC_1 PF18516.1 EAX98404.1 - 0.12 11.5 5.9 0.24 10.6 0.2 2.4 2 0 0 2 2 2 0 RuvC nuclease domain TPR_2 PF07719.17 EAX98404.1 - 0.21 11.8 4.3 7.8 6.9 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 EAX98404.1 - 0.21 11.4 1.1 0.75 9.6 1.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain Folliculin PF11704.8 EAX98405.1 - 0.00044 20.2 0.7 0.0011 18.8 0.0 2.1 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport Thioredoxin PF00085.20 EAX98406.1 - 2.2e-20 72.5 0.0 2.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAX98406.1 - 2.5e-06 27.7 0.0 0.0023 18.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EAX98406.1 - 6.8e-06 25.9 0.0 8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX98406.1 - 2.5e-05 24.7 0.0 0.00015 22.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EAX98406.1 - 5e-05 23.2 0.0 6.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EAX98406.1 - 7.5e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EAX98406.1 - 0.00011 22.1 0.2 0.11 12.4 0.0 2.1 1 1 1 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 EAX98406.1 - 0.00021 20.8 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EAX98406.1 - 0.0005 20.2 0.0 0.00083 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EAX98406.1 - 0.00078 19.4 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.10 EAX98406.1 - 0.0026 17.5 0.8 0.85 9.3 0.2 2.1 1 1 1 2 2 2 2 Redoxin DUF836 PF05768.14 EAX98406.1 - 0.0028 18.0 0.0 0.0039 17.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.6 EAX98406.1 - 0.015 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain CM2 PF03021.14 EAX98406.1 - 0.093 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M2 protein Thioredoxin PF00085.20 EAX98407.1 - 1e-17 64.0 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAX98407.1 - 7.7e-06 26.0 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EAX98407.1 - 0.00011 22.4 0.0 0.0025 18.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAX98407.1 - 0.002 18.5 0.0 0.0091 16.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EAX98407.1 - 0.0024 17.7 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EAX98407.1 - 0.003 17.0 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EAX98407.1 - 0.0043 16.8 0.0 0.0063 16.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EAX98407.1 - 0.016 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.21 EAX98407.1 - 0.081 12.8 0.1 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 AhpC/TSA family Redoxin PF08534.10 EAX98407.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 1 0 1 1 1 0 Redoxin Pkinase PF00069.25 EAX98408.1 - 1.3e-62 211.5 0.0 1.7e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98408.1 - 5.8e-39 133.9 0.0 7.8e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX98408.1 - 3.8e-09 36.0 0.1 5.9e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX98408.1 - 5.4e-08 32.5 0.0 8.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAX98408.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_5 PF13306.6 EAX98409.1 - 1.2e-44 151.4 16.9 9.9e-23 80.5 0.1 2.7 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98409.1 - 9e-10 38.2 0.2 0.22 11.3 0.1 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EAX98409.1 - 0.017 15.5 0.6 14 6.3 0.1 3.7 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) HMG_box PF00505.19 EAX98410.1 - 6.1e-24 84.2 4.3 6.1e-24 84.2 4.3 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAX98410.1 - 6.1e-16 58.8 1.4 6.1e-16 58.8 1.4 1.7 1 1 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EAX98410.1 - 0.0063 16.4 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HTH_24 PF13412.6 EAX98410.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RR_TM4-6 PF06459.12 EAX98410.1 - 1.4 8.7 12.0 1.6 8.5 12.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 EAX98410.1 - 3.4 7.7 8.2 3.9 7.5 8.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIE-A_C PF11521.8 EAX98410.1 - 6.9 7.0 13.7 1.1 9.6 0.3 2.2 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ribosomal_L3 PF00297.22 EAX98411.1 - 9.1e-141 469.1 11.3 2.7e-139 464.3 11.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.25 EAX98412.1 - 3.5e-56 190.5 0.0 4.1e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98412.1 - 1.8e-17 63.5 0.0 3.3e-17 62.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAX98412.1 - 7.3e-07 29.3 0.0 5.2e-06 26.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98412.1 - 0.0056 15.5 0.0 0.011 14.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 EAX98412.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 EAX98412.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX98412.1 - 0.073 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PTR PF12789.7 EAX98413.1 - 1.4e-34 117.9 22.5 6.2e-32 109.5 13.8 5.5 4 2 2 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX98413.1 - 0.13 12.0 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAX98415.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX98416.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ribosomal_S30 PF04758.14 EAX98418.1 - 9.6e-26 89.8 3.2 1.1e-25 89.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 EAX98419.1 - 9.6e-26 89.8 3.2 1.1e-25 89.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 KLRAQ PF10205.9 EAX98420.1 - 0.0024 18.1 8.5 0.0024 18.1 8.5 8.9 2 2 5 8 8 8 1 Predicted coiled-coil domain-containing protein DUF4413 PF14372.6 EAX98420.1 - 4.5 7.7 16.3 29 5.1 0.7 5.2 3 3 1 4 4 4 0 Domain of unknown function (DUF4413) ubiquitin PF00240.23 EAX98421.1 - 3.6e-97 318.2 11.8 1e-31 108.5 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EAX98421.1 - 1.4e-54 181.8 14.4 1.1e-17 63.6 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAX98421.1 - 3.7e-16 59.4 5.1 0.00082 19.8 0.2 4.4 1 1 2 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX98421.1 - 3.5e-11 42.9 2.1 0.04 13.9 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX98421.1 - 1.1e-10 41.7 2.7 0.058 13.8 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAX98421.1 - 8.4e-08 32.3 0.1 0.94 9.6 0.0 3.5 3 2 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAX98421.1 - 1.4e-07 32.0 0.2 0.77 10.4 0.1 3.3 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 EAX98421.1 - 1.3e-06 28.8 5.0 0.99 9.9 0.1 3.1 1 1 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 EAX98421.1 - 2.5e-05 24.2 15.3 9.3 6.4 0.1 6.0 6 0 0 6 6 6 3 Ubiquitin-like domain DUF2870 PF11069.8 EAX98421.1 - 4.3e-05 23.8 0.1 11 6.5 0.0 3.7 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) RBD PF02196.15 EAX98421.1 - 0.00013 22.0 0.0 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Raf-like Ras-binding domain Methyltrans_RNA PF04452.14 EAX98421.1 - 0.0012 18.2 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase EstA_Ig_like PF18435.1 EAX98421.1 - 0.0061 16.7 0.2 39 4.5 0.0 3.1 3 0 0 3 3 3 0 Esterase Ig-like N-terminal domain CorA PF01544.18 EAX98421.1 - 0.011 15.0 0.2 29 3.8 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein bPH_3 PF14470.6 EAX98421.1 - 0.052 13.9 2.3 25 5.3 0.0 3.4 4 0 0 4 4 4 0 Bacterial PH domain DUF3861 PF12977.7 EAX98421.1 - 0.089 13.0 0.5 81 3.5 0.0 3.2 1 1 2 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF3435 PF11917.8 EAX98421.1 - 0.11 11.4 0.0 51 2.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) FlgM PF04316.13 EAX98421.1 - 1.1 9.6 4.0 1.3e+02 3.0 0.1 3.2 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM NPM1-C PF16276.5 EAX98421.1 - 3.1 7.8 5.1 1.1e+02 2.8 0.1 3.2 3 0 0 3 3 3 0 Nucleophosmin C-terminal domain Ank_2 PF12796.7 EAX98422.1 - 1.1e-27 96.4 3.0 5e-12 46.2 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98422.1 - 1.2e-23 83.2 4.6 2.1e-08 34.5 0.0 7.1 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98422.1 - 1.6e-19 69.7 0.8 2.3e-07 31.0 0.0 5.4 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98422.1 - 6.8e-18 62.9 0.0 0.0012 19.1 0.0 6.3 5 0 0 5 5 5 4 Ankyrin repeat Pkinase_Tyr PF07714.17 EAX98422.1 - 8.1e-15 54.8 0.0 2.2e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 EAX98422.1 - 4.2e-14 52.3 0.0 0.0013 19.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Pkinase PF00069.25 EAX98422.1 - 6.5e-10 38.8 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain PriX PF18689.1 EAX98422.1 - 0.43 10.9 4.2 0.22 11.9 0.6 2.4 3 0 0 3 3 3 0 Primase X PDEase_I PF00233.19 EAX98423.1 - 4.1e-75 252.6 4.7 4.1e-75 252.6 4.7 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAX98423.1 - 3.4e-18 66.5 0.0 0.00014 22.5 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 EAX98423.1 - 1.3e-17 64.4 0.0 3.1e-06 27.5 0.0 3.8 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 EAX98423.1 - 6.3e-08 33.0 0.3 0.23 11.8 0.1 5.3 4 2 0 4 4 4 2 GAF domain Adeno_E1B_19K PF01691.16 EAX98423.1 - 0.0038 16.8 0.2 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Adenovirus E1B 19K protein / small t-antigen DUF2935 PF11155.8 EAX98423.1 - 0.64 10.4 3.1 9.3 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) Ank_2 PF12796.7 EAX98424.1 - 4.9e-38 129.6 5.4 1.7e-16 60.5 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98424.1 - 1.3e-25 89.4 0.3 5.4e-14 52.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98424.1 - 5.5e-20 71.2 0.1 4.4e-12 46.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX98424.1 - 9.4e-20 70.1 0.1 9.9e-07 28.9 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX98424.1 - 2.8e-19 67.2 0.2 5.1e-06 26.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAX98425.1 - 8.3e-39 132.1 13.3 1.9e-15 57.2 2.6 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX98425.1 - 2.7e-37 126.6 3.9 2.7e-37 126.6 3.9 4.5 5 0 0 5 5 5 3 Domain of unknown function (DUF3447) Ank PF00023.30 EAX98425.1 - 1.6e-29 101.0 8.8 2.5e-05 24.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX98425.1 - 6.6e-29 99.9 10.1 2.3e-08 34.4 0.0 8.0 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98425.1 - 5.2e-25 84.8 13.5 0.0041 17.5 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX98425.1 - 5.5e-25 87.1 11.5 4.5e-05 23.6 0.1 6.9 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98426.1 - 6.7e-54 180.4 11.0 1e-18 67.6 0.9 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98426.1 - 6.2e-33 111.8 0.6 0.0016 18.8 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAX98426.1 - 8.6e-30 102.7 0.1 7.8e-09 35.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98426.1 - 1.2e-28 95.9 0.2 0.0033 17.8 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAX98426.1 - 2.2e-27 94.7 2.6 7.2e-05 23.0 0.0 6.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) DivIC PF04977.15 EAX98426.1 - 0.00017 21.3 2.4 0.00064 19.4 2.4 2.0 1 0 0 1 1 1 1 Septum formation initiator DegS PF05384.11 EAX98426.1 - 0.0027 17.2 3.5 0.017 14.6 1.6 2.4 2 0 0 2 2 2 1 Sensor protein DegS V-SNARE PF05008.15 EAX98426.1 - 0.0038 17.6 2.1 0.0093 16.3 2.1 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus bZIP_1 PF00170.21 EAX98426.1 - 0.0053 16.8 2.1 0.021 14.9 2.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor CENP-H PF05837.12 EAX98426.1 - 0.0053 17.2 2.0 0.011 16.1 2.0 1.6 1 0 0 1 1 1 1 Centromere protein H (CENP-H) APG6_N PF17675.1 EAX98426.1 - 0.0057 17.2 1.8 0.0057 17.2 1.8 1.8 1 1 1 2 2 2 1 Apg6 coiled-coil region YabA PF06156.13 EAX98426.1 - 0.018 15.7 1.0 0.049 14.3 1.0 1.8 1 0 0 1 1 1 0 Initiation control protein YabA K-box PF01486.17 EAX98426.1 - 0.03 14.5 2.3 0.03 14.5 2.3 1.8 2 0 0 2 2 1 0 K-box region NPV_P10 PF05531.12 EAX98426.1 - 0.054 14.0 1.4 0.15 12.5 1.4 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EAX98426.1 - 0.068 13.6 2.6 0.2 12.1 2.6 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 EAX98426.1 - 0.084 12.5 5.9 0.084 12.5 3.3 1.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease B_lectin PF01453.24 EAX98426.1 - 0.15 12.6 1.7 4.1 8.0 0.1 3.0 2 1 1 3 3 3 0 D-mannose binding lectin DUF1843 PF08898.10 EAX98426.1 - 0.22 12.0 0.8 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF2205 PF10224.9 EAX98426.1 - 0.22 11.5 5.2 0.52 10.4 3.1 2.5 2 0 0 2 2 2 0 Short coiled-coil protein DUF3847 PF12958.7 EAX98426.1 - 0.67 10.1 2.9 16 5.7 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FAM76 PF16046.5 EAX98426.1 - 2.4 7.4 6.8 3.8 6.8 6.8 1.3 1 0 0 1 1 1 0 FAM76 protein FAM184 PF15665.5 EAX98427.1 - 1.4e-11 44.6 199.6 1.7e-05 24.7 35.8 9.1 1 1 7 8 8 8 6 Family with sequence similarity 184, A and B Apolipoprotein PF01442.18 EAX98427.1 - 0.0006 19.7 27.5 0.0006 19.7 27.5 6.8 1 1 5 6 6 6 2 Apolipoprotein A1/A4/E domain Mod_r PF07200.13 EAX98427.1 - 0.0068 16.5 6.3 0.0068 16.5 6.3 11.3 1 1 8 10 10 10 3 Modifier of rudimentary (Mod(r)) protein Filament PF00038.21 EAX98427.1 - 0.014 15.0 193.1 0.073 12.6 56.6 5.4 1 1 4 5 5 5 0 Intermediate filament protein DUF4407 PF14362.6 EAX98427.1 - 9.4 5.5 139.9 0.45 9.8 14.1 8.2 1 1 5 7 7 7 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 EAX98428.1 - 8.8e-23 81.9 0.1 1.1e-22 81.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX98428.1 - 0.016 15.4 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 EAX98428.1 - 0.091 12.1 0.5 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5378) VWA_3 PF13768.6 EAX98430.1 - 1.4e-12 47.8 0.0 2.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX98430.1 - 2.1e-05 24.8 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5376 PF17346.2 EAX98430.1 - 0.54 10.6 7.9 0.45 10.9 5.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5376) VIT PF08487.10 EAX98431.1 - 4.2e-16 59.1 0.0 5.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain BTRD1 PF17660.1 EAX98431.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 SNF2_N PF00176.23 EAX98432.1 - 6.1e-53 179.8 0.5 6.1e-53 179.8 0.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAX98432.1 - 4.6e-19 68.8 0.1 4.6e-19 68.8 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 EAX98432.1 - 6.6e-19 67.6 7.5 6.7e-12 45.1 0.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 EAX98432.1 - 8.7e-17 60.7 0.1 1.9e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EAX98432.1 - 1.8e-15 56.9 0.0 6.8e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus ResIII PF04851.15 EAX98432.1 - 1.1e-07 32.0 0.1 1.1e-07 32.0 0.1 3.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAX98432.1 - 8.1e-06 25.2 0.2 3.2e-05 23.2 0.2 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EAX98432.1 - 0.00085 19.1 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RelB_N PF18506.1 EAX98432.1 - 0.071 12.9 0.4 0.24 11.2 0.4 2.0 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain NOP5NT PF08156.13 EAX98432.1 - 0.21 12.0 2.5 3.4 8.1 0.2 3.1 2 0 0 2 2 2 0 NOP5NT (NUC127) domain DHOR PF06537.11 EAX98434.1 - 0.046 12.4 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase PTR PF12789.7 EAX98435.1 - 2.8e-20 72.1 20.9 6.6e-17 61.3 1.4 3.9 5 0 0 5 5 5 3 Phage tail repeat like DnaJ PF00226.31 EAX98436.1 - 1.4e-23 82.8 3.0 7.8e-23 80.4 3.0 2.5 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EAX98436.1 - 1.4e-05 25.2 3.9 4.9e-05 23.5 3.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EAX98436.1 - 0.017 15.9 1.5 0.046 14.6 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Orf78 PF06024.12 EAX98436.1 - 0.025 14.9 0.1 0.025 14.9 0.1 5.3 3 1 0 3 3 3 0 Orf78 (ac78) zf-C2H2_2 PF12756.7 EAX98436.1 - 0.13 12.6 4.7 0.13 12.6 1.9 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3899 PF13038.6 EAX98436.1 - 0.29 11.7 0.1 0.29 11.7 0.1 5.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3899) DUF3377 PF11857.8 EAX98436.1 - 0.33 10.9 2.8 0.78 9.7 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) zf-C2H2 PF00096.26 EAX98436.1 - 0.43 11.1 3.7 1.2 9.7 3.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1676 PF07898.13 EAX98436.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1676) DUF3169 PF11368.8 EAX98436.1 - 3.8 6.9 6.7 0.25 10.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Vps39_2 PF10367.9 EAX98437.1 - 5.4e-05 23.6 0.5 7.2e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 mCpol PF18182.1 EAX98437.1 - 0.0013 19.1 0.3 0.0022 18.3 0.3 1.3 1 0 0 1 1 1 1 minimal CRISPR polymerase domain DUF5101 PF17031.5 EAX98438.1 - 0.055 13.6 0.2 0.084 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) PG_binding_4 PF12229.8 EAX98438.1 - 0.071 13.4 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Zn_ribbon_recom PF13408.6 EAX98438.1 - 4.2 8.0 6.9 4.5 7.9 6.0 1.5 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_L29e PF01779.17 EAX98440.1 - 6.2e-14 52.0 7.4 8e-14 51.7 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Sulfatase PF00884.23 EAX98441.1 - 2.4e-16 60.0 0.1 3.3e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase gp32 PF08804.10 EAX98441.1 - 0.042 13.9 1.4 0.065 13.3 1.4 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like SIR2 PF02146.17 EAX98442.1 - 2.4e-52 177.4 0.0 3.1e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Raptor_N PF14538.6 EAX98444.1 - 2.3e-34 118.5 0.0 8.9e-34 116.6 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 EAX98444.1 - 2e-09 37.7 0.0 9.3e-09 35.6 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EAX98444.1 - 5.8e-07 29.2 0.0 0.22 11.8 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EAX98444.1 - 6.6e-05 23.3 0.0 0.34 11.5 0.0 3.4 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 EAX98444.1 - 8.4e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAX98444.1 - 0.0067 17.0 0.1 0.56 10.8 0.0 2.7 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EAX98444.1 - 0.01 14.4 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_PBS PF03130.16 EAX98444.1 - 0.068 13.9 0.0 1 10.2 0.0 2.8 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Pkinase PF00069.25 EAX98445.1 - 4.1e-39 134.5 0.0 5.4e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98445.1 - 2.4e-17 63.1 0.0 3.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EAX98445.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EAX98445.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_N PF01602.20 EAX98447.1 - 1.4e-35 122.8 9.4 2.2e-35 122.3 9.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EAX98447.1 - 0.0012 19.0 0.3 0.012 15.8 0.1 2.5 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain BRO1 PF03097.18 EAX98448.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain Gly_rich PF12810.7 EAX98449.1 - 1.9e-61 208.1 27.6 2.2e-61 207.9 27.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Tctex-1 PF03645.13 EAX98450.1 - 0.006 16.8 0.0 0.016 15.4 0.0 1.8 2 1 0 2 2 2 1 Tctex-1 family Swm2 PF17083.5 EAX98450.1 - 0.008 16.2 2.4 0.019 15.0 1.5 1.9 1 1 1 2 2 2 1 Nucleolar protein Swm2 Ank_2 PF12796.7 EAX98451.1 - 1e-31 109.3 1.5 5.6e-20 71.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98451.1 - 4.4e-25 87.7 1.9 1.7e-12 47.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98451.1 - 1.2e-23 82.9 3.6 1.9e-11 43.9 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98451.1 - 3.2e-20 71.6 0.3 4.1e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAX98451.1 - 2.7e-19 67.2 0.7 2.1e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat LRR_5 PF13306.6 EAX98452.1 - 4.5e-280 912.5 238.1 5.2e-31 107.3 5.3 12.7 1 1 12 14 14 14 14 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98452.1 - 7.8e-31 105.6 43.6 0.00088 19.0 0.0 19.5 14 6 11 25 25 25 16 Leucine rich repeat Ank PF00023.30 EAX98453.1 - 1.7e-86 281.2 33.8 1.1e-06 28.8 0.1 15.6 14 1 0 14 14 14 14 Ankyrin repeat Ank_2 PF12796.7 EAX98453.1 - 7.7e-85 279.6 50.4 8.9e-16 58.3 1.8 9.6 4 3 7 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98453.1 - 9.8e-82 268.4 25.8 1.2e-14 54.4 0.3 14.7 6 3 8 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98453.1 - 6.1e-72 236.7 24.0 1.8e-13 50.4 0.6 11.1 6 5 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98453.1 - 1.7e-61 196.9 25.2 1.8e-05 24.7 0.1 16.4 16 0 0 16 16 16 12 Ankyrin repeat DUF3447 PF11929.8 EAX98453.1 - 2.9e-29 100.9 19.6 3.1e-29 100.7 3.9 5.3 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) UDPG_MGDP_dh_C PF03720.15 EAX98453.1 - 0.0023 18.3 0.5 10 6.6 0.0 4.3 4 2 0 4 4 4 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF655 PF04919.12 EAX98453.1 - 0.0028 17.7 0.2 4.7 7.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF655) CCDC84 PF14968.6 EAX98453.1 - 0.015 15.0 5.2 4.9 6.7 0.7 4.3 1 1 1 3 3 3 0 Coiled coil protein 84 DUF3447 PF11929.8 EAX98454.1 - 4.1e-24 84.3 7.8 4.1e-24 84.3 7.8 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) T5orf172 PF10544.9 EAX98455.1 - 3.8e-07 30.6 0.3 7.5e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX98456.1 - 2.8e-43 146.3 0.6 6.7e-43 145.1 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX98456.1 - 0.0049 17.5 0.1 0.017 15.7 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family Pox_A32 PF04665.12 EAX98457.1 - 5.2e-07 29.4 2.2 5.2e-07 29.4 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX98457.1 - 2.1e-05 24.8 0.2 0.00025 21.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX98457.1 - 4e-05 23.4 0.3 0.34 10.6 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX98457.1 - 0.00018 21.6 3.6 0.00044 20.3 3.6 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX98457.1 - 0.00052 19.8 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX98457.1 - 0.0019 17.9 0.4 0.013 15.2 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX98457.1 - 0.0019 18.0 0.9 0.0041 16.9 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX98457.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX98457.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX98457.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX98457.1 - 0.094 13.1 0.1 0.78 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX98457.1 - 0.18 12.1 4.1 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) EMC3_TMCO1 PF01956.16 EAX98458.1 - 2.1e-28 99.2 1.3 2.9e-28 98.7 1.3 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Mer2 PF09074.10 EAX98458.1 - 0.0096 15.8 2.1 0.014 15.2 2.1 1.2 1 0 0 1 1 1 1 Mer2 CHD5 PF04420.14 EAX98458.1 - 0.018 14.9 0.4 0.037 13.9 0.4 1.5 1 0 0 1 1 1 0 CHD5-like protein DUF2951 PF11166.8 EAX98458.1 - 0.025 14.8 2.0 0.04 14.1 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) LapA_dom PF06305.11 EAX98458.1 - 0.046 13.6 2.4 0.052 13.4 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2203 PF09969.9 EAX98458.1 - 0.076 13.7 0.1 0.1 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Alpha-2-MRAP_C PF06401.11 EAX98458.1 - 0.078 12.9 6.3 0.11 12.5 6.3 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3810 PF12725.7 EAX98458.1 - 0.087 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4710 PF15828.5 EAX98458.1 - 0.26 11.4 3.5 0.47 10.6 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) FlxA PF14282.6 EAX98458.1 - 0.8 9.7 9.3 1.2 9.2 9.3 1.2 1 0 0 1 1 1 0 FlxA-like protein GRAB PF10375.9 EAX98458.1 - 2.1 8.4 4.1 0.66 9.9 0.3 2.0 2 0 0 2 2 2 0 GRIP-related Arf-binding domain IFT20 PF14931.6 EAX98459.1 - 0.019 15.1 14.1 0.019 15.1 14.1 3.6 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 TolA_bind_tri PF16331.5 EAX98459.1 - 0.055 13.6 0.6 0.055 13.6 0.6 5.4 3 1 2 6 6 6 0 TolA binding protein trimerisation Mac PF12464.8 EAX98459.1 - 0.25 11.6 2.4 5.2 7.4 0.1 3.4 3 0 0 3 3 3 0 Maltose acetyltransferase GrpE PF01025.19 EAX98459.1 - 0.29 10.8 0.1 0.29 10.8 0.1 4.6 1 1 2 4 4 4 0 GrpE TMF_TATA_bd PF12325.8 EAX98459.1 - 0.39 10.9 32.0 0.76 10.0 7.1 4.6 2 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding AFP_2 PF18815.1 EAX98459.1 - 0.76 10.1 4.1 22 5.4 0.3 3.6 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat CRIC_ras_sig PF10534.9 EAX98459.1 - 1.3 9.3 12.2 0.56 10.4 0.8 4.0 3 1 0 3 3 3 0 Connector enhancer of kinase suppressor of ras Filament PF00038.21 EAX98459.1 - 1.3 8.5 35.2 3.2 7.3 4.8 3.8 1 1 3 4 4 4 0 Intermediate filament protein Rootletin PF15035.6 EAX98459.1 - 5.7 6.9 36.1 1.6 8.8 6.4 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Phe_hydrox_dim PF07976.12 EAX98459.1 - 7.8 6.5 9.7 5.1 7.1 1.7 3.2 1 1 2 3 3 3 0 Phenol hydroxylase, C-terminal dimerisation domain Ank_2 PF12796.7 EAX98460.1 - 5.7e-53 177.4 6.8 2.1e-20 73.1 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98460.1 - 5.1e-28 97.1 0.7 8.2e-10 39.0 0.1 5.1 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98460.1 - 9.4e-24 80.9 0.1 0.00015 21.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAX98460.1 - 5.9e-23 80.6 0.4 4e-07 30.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX98460.1 - 1.2e-22 79.3 0.1 4.8e-05 23.6 0.2 6.5 6 0 0 6 6 6 4 Ankyrin repeat TSC22 PF01166.18 EAX98460.1 - 0.02 15.2 0.6 0.079 13.3 0.6 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family Spc29 PF17082.5 EAX98460.1 - 0.024 14.5 4.0 0.037 13.9 4.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DivIC PF04977.15 EAX98460.1 - 0.025 14.4 2.6 0.032 14.0 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator Fzo_mitofusin PF04799.13 EAX98460.1 - 0.027 14.0 2.5 0.044 13.3 1.7 1.6 1 1 0 1 1 1 0 fzo-like conserved region VPS13_C PF16909.5 EAX98460.1 - 0.033 14.0 0.6 0.059 13.1 0.6 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Med9 PF07544.13 EAX98460.1 - 0.061 13.4 2.7 0.18 11.9 2.7 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GIT_CC PF16559.5 EAX98460.1 - 0.079 12.8 1.9 0.17 11.7 1.5 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RPAP3_C PF13877.6 EAX98460.1 - 0.15 12.6 2.2 0.94 10.1 1.0 2.6 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 Acetyltransf_11 PF13720.6 EAX98460.1 - 0.16 12.4 2.1 4.5 7.8 0.1 2.7 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 P4Ha_N PF08336.11 EAX98460.1 - 0.23 11.5 4.6 0.65 10.0 4.6 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GPS2_interact PF15784.5 EAX98463.1 - 0.037 14.5 0.8 0.051 14.0 0.8 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98463.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TonB_N PF16031.5 EAX98464.1 - 0.0031 18.0 20.1 0.0031 18.0 20.1 1.7 2 1 0 2 2 2 1 TonB polyproline region Trypan_PARP PF05887.11 EAX98464.1 - 0.016 15.2 10.4 0.024 14.6 10.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX98464.1 - 6.6 7.2 7.3 9.7 6.6 7.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KilA-N PF04383.13 EAX98466.1 - 7.5e-41 138.5 1.8 8.7e-41 138.3 0.2 1.9 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAX98466.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family RRP36 PF06102.12 EAX98466.1 - 0.27 11.2 7.0 0.17 11.8 3.0 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Amidase02_C PF12123.8 EAX98468.1 - 0.011 15.5 0.1 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98469.1 - 4.7e-68 228.4 7.9 8.4e-68 227.6 7.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Ank_2 PF12796.7 EAX98472.1 - 1.9e-09 38.0 0.1 6.2e-09 36.3 0.0 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98472.1 - 9.9e-08 32.4 0.0 5.1e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98472.1 - 1e-07 32.1 0.0 3.2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98472.1 - 1e-07 32.0 0.1 0.055 14.0 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAX98472.1 - 2.5e-07 30.4 0.3 0.18 12.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ribosomal_L1 PF00687.21 EAX98473.1 - 1.1e-33 116.7 4.4 1.3e-33 116.4 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Sec10 PF07393.11 EAX98473.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 UBA_4 PF14555.6 EAX98474.1 - 1.8e-06 27.7 0.1 3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EAX98474.1 - 0.0082 15.8 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain DnaJ_C PF01556.18 EAX98475.1 - 2.2e-21 76.5 0.0 2.9e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX98475.1 - 3e-12 46.5 1.0 5.8e-12 45.6 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain E1_FCCH PF16190.5 EAX98475.1 - 0.12 12.6 0.1 0.68 10.2 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain DUF3447 PF11929.8 EAX98476.1 - 0.0094 15.9 3.7 0.025 14.5 0.3 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX98478.1 - 3e-187 599.8 95.5 1.2e-08 35.0 0.1 28.1 28 0 0 28 28 28 28 Ankyrin repeat Ank_4 PF13637.6 EAX98478.1 - 3.6e-180 582.3 60.9 8.3e-13 48.6 0.2 26.7 11 11 18 29 29 29 28 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98478.1 - 5e-166 539.8 127.5 8.1e-20 71.2 6.6 14.7 2 2 11 14 14 14 14 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98478.1 - 1.5e-117 382.1 64.8 6.1e-10 39.2 0.1 16.9 12 3 4 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98478.1 - 4.7e-109 343.0 62.9 0.00022 21.4 0.0 28.4 28 0 0 28 28 28 18 Ankyrin repeat Ufm1 PF03671.14 EAX98478.1 - 1.5e-22 79.5 10.4 2.2 8.5 0.0 13.1 11 2 2 13 13 13 9 Ubiquitin fold modifier 1 protein DUF3130 PF11328.8 EAX98478.1 - 6.8e-08 32.6 50.3 17 5.7 0.1 14.9 6 5 2 15 15 15 0 Protein of unknown function (DUF3130 Cystatin PF00031.21 EAX98478.1 - 2.2e-06 27.9 33.4 20 5.6 0.0 11.8 11 0 0 11 11 11 0 Cystatin domain UCR_6-4kD PF08997.10 EAX98478.1 - 4.7e-05 23.2 0.0 1.4e+02 2.5 0.0 6.9 8 0 0 8 8 8 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein YcxB PF14317.6 EAX98478.1 - 0.00015 21.3 3.4 8.4 6.2 0.0 7.5 13 0 0 13 13 13 1 YcxB-like protein UL141 PF16758.5 EAX98478.1 - 0.058 13.1 0.2 36 4.0 0.0 3.2 2 1 1 3 3 3 0 Herpes-like virus membrane glycoprotein UL141 AAA PF00004.29 EAX98479.1 - 1e-44 152.2 0.1 2.8e-44 150.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAX98479.1 - 6.9e-15 54.6 0.2 6e-14 51.6 0.3 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 EAX98479.1 - 5e-08 33.3 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAX98479.1 - 1.2e-07 31.8 0.3 5e-07 29.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAX98479.1 - 1.8e-07 31.7 0.9 5.9e-06 26.8 0.1 3.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EAX98479.1 - 3.9e-05 23.9 0.4 0.0057 16.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAX98479.1 - 4e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DivIC PF04977.15 EAX98479.1 - 0.00029 20.5 2.1 0.00063 19.5 2.1 1.5 1 0 0 1 1 1 1 Septum formation initiator TolA_bind_tri PF16331.5 EAX98479.1 - 0.00059 19.9 3.3 0.0011 19.0 1.2 2.2 2 0 0 2 2 2 1 TolA binding protein trimerisation TIP49 PF06068.13 EAX98479.1 - 0.00069 18.9 0.1 0.0016 17.7 0.0 1.6 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EAX98479.1 - 0.00086 19.5 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAX98479.1 - 0.0017 17.7 0.1 0.0065 15.9 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 EAX98479.1 - 0.0021 18.6 0.3 0.024 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAX98479.1 - 0.003 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EAX98479.1 - 0.0034 17.8 0.0 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 EAX98479.1 - 0.005 17.1 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EAX98479.1 - 0.0052 16.6 0.0 0.017 15.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 EAX98479.1 - 0.0071 15.1 0.6 0.32 9.6 0.3 2.1 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.11 EAX98479.1 - 0.0078 15.1 1.6 0.015 14.2 1.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Mg_chelatase PF01078.21 EAX98479.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAX98479.1 - 0.011 15.4 0.1 0.064 13.0 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EAX98479.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAX98479.1 - 0.013 15.2 0.1 0.032 14.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain SlyX PF04102.12 EAX98479.1 - 0.015 15.9 0.7 0.053 14.2 0.7 2.0 1 0 0 1 1 1 0 SlyX TMF_TATA_bd PF12325.8 EAX98479.1 - 0.015 15.5 1.3 0.032 14.4 1.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 EAX98479.1 - 0.021 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_7 PF12775.7 EAX98479.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EAX98479.1 - 0.024 14.2 0.1 0.099 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Filament PF00038.21 EAX98479.1 - 0.026 14.1 1.1 0.047 13.3 1.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Parvo_NS1 PF01057.17 EAX98479.1 - 0.032 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fmp27_WPPW PF10359.9 EAX98479.1 - 0.032 13.1 0.2 0.06 12.2 0.2 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TsaE PF02367.17 EAX98479.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EAX98479.1 - 0.035 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EAX98479.1 - 0.042 13.8 0.0 0.67 9.9 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ATG16 PF08614.11 EAX98479.1 - 0.043 14.0 0.6 0.071 13.3 0.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_11 PF13086.6 EAX98479.1 - 0.045 13.5 0.4 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.11 EAX98479.1 - 0.046 14.1 1.6 0.086 13.2 0.8 2.0 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Prot_ATP_ID_OB PF16450.5 EAX98479.1 - 0.046 13.7 1.4 0.076 13.0 0.1 2.1 3 0 0 3 3 1 0 Proteasomal ATPase OB C-terminal domain PhoH PF02562.16 EAX98479.1 - 0.051 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MbeD_MobD PF04899.12 EAX98479.1 - 0.062 13.4 0.2 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 MbeD/MobD like zf-C4H2 PF10146.9 EAX98479.1 - 0.063 13.6 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Zeta_toxin PF06414.12 EAX98479.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EAX98479.1 - 0.091 13.3 0.2 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Phage_GP20 PF06810.11 EAX98479.1 - 0.091 12.6 1.5 0.2 11.4 0.6 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 EAX98479.1 - 1.5 9.0 4.4 1 9.5 0.5 2.1 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 EAX98479.1 - 1.8 9.1 5.9 0.19 12.2 1.4 1.7 2 0 0 2 2 1 0 Cell division protein ZapB RnlB_antitoxin PF15933.5 EAX98480.1 - 0.57 10.5 5.2 0.71 10.2 2.7 2.5 1 1 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA Tn7_Tnp_TnsA_C PF08721.11 EAX98480.1 - 0.99 10.1 7.7 20 5.9 0.3 4.1 5 0 0 5 5 5 0 TnsA endonuclease C terminal GATase PF00117.28 EAX98481.1 - 1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EAX98481.1 - 0.006 16.2 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EAX98481.1 - 0.018 14.8 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase C26 EpuA PF11772.8 EAX98482.1 - 0.012 15.2 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DUF3839 PF12943.7 EAX98483.1 - 3.8e-119 396.5 12.6 4.9e-119 396.2 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX98483.1 - 0.028 14.9 2.9 1.8 9.0 0.0 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NTP_transf_6 PF06042.11 EAX98483.1 - 0.23 11.3 2.4 0.45 10.3 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Pox_A32 PF04665.12 EAX98484.1 - 4.8e-07 29.5 1.9 4.8e-07 29.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX98484.1 - 3.3e-05 24.2 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX98484.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX98484.1 - 0.0002 21.4 3.7 0.00049 20.2 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX98484.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX98484.1 - 0.0014 18.3 0.4 0.01 15.5 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX98484.1 - 0.0018 18.1 0.7 0.0047 16.7 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX98484.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX98484.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX98484.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX98484.1 - 0.095 13.1 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX98484.1 - 0.24 11.8 3.2 0.73 10.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX98484.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX98485.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX98486.1 - 4e-58 195.4 4.2 4.5e-58 195.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Endosulfine PF04667.17 EAX98487.1 - 0.03 14.5 1.1 0.057 13.6 1.1 1.7 1 1 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Actin PF00022.19 EAX98488.1 - 6.1e-37 127.2 0.0 4.4e-15 55.2 0.0 3.0 1 1 2 3 3 3 3 Actin MreB_Mbl PF06723.13 EAX98488.1 - 0.0051 15.7 0.1 0.024 13.5 0.1 2.1 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EAX98488.1 - 0.096 13.1 0.0 0.63 10.5 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA Sugar_tr PF00083.24 EAX98489.1 - 5.9e-45 154.0 32.4 5.1e-35 121.2 20.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX98489.1 - 1.4e-13 50.5 26.9 5.9e-10 38.6 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAX98489.1 - 0.034 12.6 4.9 0.061 11.7 1.2 2.1 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 EAX98490.1 - 1.4e-05 24.6 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 EAX98491.1 - 2.5e-41 142.2 38.7 6.7e-41 140.8 37.2 2.0 2 0 0 2 2 2 1 Glycine rich protein OppC_N PF12911.7 EAX98492.1 - 0.095 12.7 0.1 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C YrhK PF14145.6 EAX98492.1 - 5.7 6.9 8.9 1.7e+02 2.2 9.5 2.1 1 1 0 1 1 1 0 YrhK-like protein Imm8 PF15586.6 EAX98493.1 - 0.025 14.6 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 8 But2 PF09792.9 EAX98493.1 - 0.051 14.0 0.2 0.085 13.3 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain C2 PF00168.30 EAX98493.1 - 0.055 13.8 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain CC2D2AN-C2 PF15625.6 EAX98494.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 EAX98494.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 0 C2 domain YrhC PF14143.6 EAX98494.1 - 0.017 15.2 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 YrhC-like protein PTR PF12789.7 EAX98495.1 - 1.8e-13 50.3 29.9 1.9e-08 34.2 5.2 6.1 6 0 0 6 6 6 3 Phage tail repeat like DUF2175 PF09943.9 EAX98495.1 - 0.094 13.0 4.6 0.25 11.7 0.7 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Amidase02_C PF12123.8 EAX98496.1 - 0.0096 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98497.1 - 7.8e-68 227.7 1.5 9.9e-68 227.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98497.1 - 0.069 13.5 0.2 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta Peripla_BP_2 PF01497.18 EAX98499.1 - 0.0031 17.1 0.1 0.0083 15.7 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein DUF3781 PF12636.7 EAX98500.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Cohesin PF00963.18 EAX98501.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Cohesin domain WASH-7_C PF14746.6 EAX98502.1 - 0.045 13.5 4.6 0.11 12.2 1.1 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MCM6_C PF18263.1 EAX98502.1 - 0.22 11.8 5.6 0.73 10.1 5.6 1.8 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pox_Ag35 PF03286.14 EAX98502.1 - 0.54 10.0 5.3 0.86 9.4 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sugar_tr PF00083.24 EAX98504.1 - 1.5e-50 172.4 33.1 4.1e-49 167.7 33.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAX98504.1 - 4e-29 101.7 28.9 6.2e-29 101.0 28.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EAX98504.1 - 0.031 14.6 3.8 4.2 7.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2387 PF09526.10 EAX98506.1 - 0.067 13.4 0.4 0.16 12.1 0.4 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Gly_rich PF12810.7 EAX98507.1 - 3.5e-46 158.1 50.7 4.8e-46 157.7 50.7 1.2 1 0 0 1 1 1 1 Glycine rich protein PrcB_C PF14343.6 EAX98507.1 - 0.45 10.7 3.4 12 6.1 0.6 3.1 3 0 0 3 3 3 0 PrcB C-terminal Pkinase PF00069.25 EAX98509.1 - 6.9e-13 48.6 0.0 1.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Adaptin_N PF01602.20 EAX98509.1 - 2.4e-06 26.4 3.0 1.2e-05 24.1 1.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Pkinase_Tyr PF07714.17 EAX98509.1 - 0.0053 16.1 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase LexA_DNA_bind PF01726.16 EAX98509.1 - 0.021 14.6 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 LexA DNA binding domain Kdo PF06293.14 EAX98509.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAP206 PF12018.8 EAX98509.1 - 0.053 13.0 0.2 0.23 11.0 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function Cnd1 PF12717.7 EAX98509.1 - 0.072 13.1 3.8 0.66 10.0 0.3 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SapB_2 PF03489.17 EAX98510.1 - 0.08 13.1 0.1 0.5 10.5 0.1 2.5 1 0 0 1 1 1 0 Saposin-like type B, region 2 Chlam_PMP PF02415.17 EAX98511.1 - 0.06 13.9 18.1 3.1 8.4 3.6 4.8 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat VanW PF04294.13 EAX98511.1 - 0.092 12.4 3.2 0.68 9.6 0.2 2.6 2 1 0 2 2 2 0 VanW like protein DUF3319 PF11782.8 EAX98511.1 - 0.11 12.5 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3319) Mid2 PF04478.12 EAX98512.1 - 0.0011 18.8 2.2 0.0027 17.5 1.9 1.7 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EAX98512.1 - 0.0031 16.9 3.1 0.006 16.0 3.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EAX98512.1 - 0.0075 17.1 0.0 0.16 12.8 0.0 2.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 EAX98512.1 - 0.014 13.8 1.0 0.023 13.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Cytomega_TRL10 PF06084.11 EAX98512.1 - 0.07 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein TMEM154 PF15102.6 EAX98512.1 - 0.23 11.4 4.0 0.12 12.3 0.5 2.1 1 1 1 2 2 2 0 TMEM154 protein family Gly_rich PF12810.7 EAX98513.1 - 8.5e-36 124.1 37.9 1.3e-35 123.5 37.9 1.2 1 0 0 1 1 1 1 Glycine rich protein SesA PF17107.5 EAX98514.1 - 0.14 12.3 2.4 0.11 12.6 0.4 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_MLP1_2 PF07926.12 EAX98516.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX98516.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX98516.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAX98518.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_5 PF13306.6 EAX98519.1 - 1.1e-07 31.9 10.1 0.00027 20.9 0.4 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98519.1 - 3.3e-05 23.5 0.4 0.00076 19.2 0.1 2.5 3 0 0 3 3 3 1 Leucine rich repeat GNVR PF13807.6 EAX98520.1 - 0.084 12.8 1.1 0.18 11.7 1.0 1.7 1 1 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF2207 PF09972.9 EAX98520.1 - 0.099 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR_5 PF13306.6 EAX98521.1 - 1e-05 25.5 12.6 0.0063 16.5 2.2 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98521.1 - 0.0004 20.1 0.1 0.0089 15.8 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat DUF1084 PF06454.11 EAX98521.1 - 0.018 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) CENP-T_C PF15511.6 EAX98522.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAX98522.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAX98522.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAX98522.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAX98522.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAX98522.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAX98522.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAX98522.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EAX98523.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAX98523.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAX98523.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAX98523.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein STE2 PF02116.15 EAX98524.1 - 0.0098 15.2 0.2 0.021 14.1 0.2 1.5 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF4107 PF13389.6 EAX98527.1 - 2.1e-65 219.8 12.5 1e-63 214.3 12.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98527.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX98528.1 - 0.0034 17.0 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX98530.1 - 1.3e-22 79.8 0.6 2.4e-22 78.9 0.6 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX98530.1 - 0.038 14.0 0.5 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chal_sti_synt_N PF00195.19 EAX98530.1 - 0.15 11.5 0.3 0.41 10.0 0.3 1.8 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX98531.1 - 4.3e-131 435.6 8.6 5.4e-131 435.3 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) LD_cluster2 PF18163.1 EAX98531.1 - 0.18 11.3 0.1 0.51 9.8 0.1 1.8 1 1 0 1 1 1 0 SLOG cluster2 Rx_N PF18052.1 EAX98531.1 - 0.64 10.3 2.3 3.1 8.1 0.0 2.6 2 1 1 3 3 3 0 Rx N-terminal domain HECT PF00632.25 EAX98533.1 - 1.8e-43 149.2 2.1 1.1e-41 143.3 2.1 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FTH PF01827.27 EAX98533.1 - 0.035 13.9 0.8 0.067 13.0 0.8 1.5 1 1 0 1 1 1 0 FTH domain Terminase_3C PF17288.2 EAX98533.1 - 0.094 13.1 0.3 4.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Terminase RNAseH like domain MEDS PF14417.6 EAX98534.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Nse4_C PF08743.10 EAX98536.1 - 1.9e-12 47.3 0.3 1.3e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Nse4 C-terminal DHHA2 PF02833.14 EAX98536.1 - 0.015 15.5 0.5 5.7 7.1 0.2 2.2 2 0 0 2 2 2 0 DHHA2 domain UPF0449 PF15136.6 EAX98537.1 - 0.00059 20.3 3.4 0.00059 20.3 3.4 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 DUF5624 PF18538.1 EAX98537.1 - 0.0019 18.3 3.2 0.48 10.5 0.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5624) KELK PF15796.5 EAX98537.1 - 0.0023 18.3 6.4 0.0056 17.1 6.4 1.6 1 0 0 1 1 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Herpes_UL6 PF01763.16 EAX98537.1 - 0.0038 15.8 1.8 0.0057 15.2 1.8 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like Golgin_A5 PF09787.9 EAX98537.1 - 0.0042 16.6 8.1 0.0042 16.6 8.1 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 5 Filament PF00038.21 EAX98537.1 - 0.0077 15.8 6.7 0.0077 15.8 6.7 1.7 2 0 0 2 2 2 1 Intermediate filament protein Rootletin PF15035.6 EAX98537.1 - 0.018 15.1 10.7 0.018 15.1 10.7 1.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TolA_bind_tri PF16331.5 EAX98537.1 - 0.21 11.7 11.0 0.36 11.0 9.3 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation APG6_N PF17675.1 EAX98537.1 - 0.24 11.9 14.4 0.12 12.9 10.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 EAX98537.1 - 0.48 9.7 13.1 0.2 11.0 10.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EAX98537.1 - 0.52 10.3 14.7 0.67 10.0 3.8 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 EAX98537.1 - 0.66 10.1 13.2 0.15 12.1 9.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2877 PF11392.8 EAX98537.1 - 0.78 10.5 2.9 21 5.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) IFT20 PF14931.6 EAX98537.1 - 1.1 9.4 11.8 1.6 9.0 10.7 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF4472 PF14739.6 EAX98537.1 - 1.3 9.8 12.9 0.26 12.1 9.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF2780 PF11075.8 EAX98537.1 - 1.3 9.1 11.6 2.7 8.1 2.2 2.8 1 1 1 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) Cas_Csn2 PF09711.10 EAX98537.1 - 1.4 8.6 12.3 0.65 9.6 2.1 2.9 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_Csn2) CENP-F_leu_zip PF10473.9 EAX98537.1 - 1.6 8.8 16.4 1.8 8.6 7.8 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EAX98537.1 - 1.8 8.8 12.7 0.37 11.0 8.7 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 EAX98537.1 - 3.5 7.8 19.5 0.22 11.7 12.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 EAX98537.1 - 6.7 4.5 10.0 5.7 4.7 9.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.6 EAX98537.1 - 9.3 5.8 12.3 17 4.9 12.3 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pyr_redox_2 PF07992.14 EAX98538.1 - 6.3e-40 137.2 2.4 9.6e-40 136.6 2.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAX98538.1 - 2.8e-17 62.9 2.5 7.1e-16 58.3 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAX98538.1 - 5.5e-10 39.7 0.8 7.9e-09 36.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAX98538.1 - 2.9e-06 26.7 0.1 0.0012 18.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 EAX98538.1 - 1.1e-05 25.0 0.1 1.1e-05 25.0 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAX98538.1 - 0.00021 20.5 1.4 0.0074 15.4 0.2 2.7 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 EAX98538.1 - 0.00029 20.1 0.2 0.0077 15.4 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EAX98538.1 - 0.00057 19.1 8.3 0.0017 17.6 1.0 3.6 3 1 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EAX98538.1 - 0.0015 18.8 0.2 0.0037 17.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAX98538.1 - 0.0034 16.1 1.7 0.24 10.0 0.0 2.9 3 1 0 3 3 3 2 HI0933-like protein DUF3447 PF11929.8 EAX98539.1 - 2.1e-38 130.1 8.2 2.1e-38 130.1 8.2 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98539.1 - 1.3e-28 98.9 7.9 8.7e-11 42.1 0.1 5.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98539.1 - 3.1e-28 98.2 10.2 3.4e-17 62.8 2.7 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98539.1 - 1.1e-24 85.7 3.7 1.5e-07 31.5 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX98539.1 - 1.8e-21 73.9 9.5 3.5e-05 23.8 0.1 6.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX98539.1 - 3.6e-17 62.2 5.6 7.7e-10 38.8 0.2 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) LRR_5 PF13306.6 EAX98540.1 - 5e-109 359.5 84.7 2.8e-34 117.8 18.1 5.4 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98540.1 - 1.2e-21 76.2 19.4 0.00013 21.6 0.0 10.3 4 3 7 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 EAX98540.1 - 0.36 11.3 0.1 0.36 11.3 0.1 9.4 7 2 2 9 9 9 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAX98540.1 - 6.4 7.0 19.0 0.33 11.2 1.6 6.9 6 3 1 7 7 7 0 FNIP Repeat Pentapeptide_3 PF13576.6 EAX98540.1 - 8.5 6.6 11.9 0.51 10.5 0.6 4.4 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Takusan PF04822.13 EAX98541.1 - 0.0082 16.0 0.1 0.0082 16.0 0.1 2.6 3 0 0 3 3 3 1 Takusan FYRN PF05964.14 EAX98541.1 - 0.12 12.2 1.9 0.68 9.8 1.9 2.1 1 1 0 1 1 1 0 F/Y-rich N-terminus LRR_5 PF13306.6 EAX98542.1 - 5.2e-60 201.0 46.6 8.3e-31 106.6 10.0 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98542.1 - 5.2e-10 38.9 0.2 0.032 14.0 0.0 5.1 4 1 1 5 5 5 2 Leucine rich repeat Podoplanin PF05808.11 EAX98542.1 - 1.9e-06 28.0 0.1 3.4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Podoplanin DUF5305 PF17231.2 EAX98542.1 - 0.00011 21.7 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5305) SKG6 PF08693.10 EAX98542.1 - 0.00011 21.5 1.0 0.0002 20.7 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD99L2 PF12301.8 EAX98542.1 - 0.0012 19.2 0.2 0.0019 18.5 0.2 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF4690 PF15756.5 EAX98542.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2407_C PF13373.6 EAX98542.1 - 0.039 14.1 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain MtrG PF04210.13 EAX98542.1 - 0.13 12.1 0.6 0.33 10.9 0.6 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Adeno_E3_CR2 PF02439.15 EAX98542.1 - 0.17 11.6 5.7 0.94 9.3 5.7 2.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EAX98542.1 - 0.24 11.4 2.1 0.47 10.4 2.1 1.4 1 0 0 1 1 1 0 Syndecan domain PMP1_2 PF08114.11 EAX98542.1 - 0.68 9.7 3.3 1.4 8.7 3.3 1.5 1 0 0 1 1 1 0 ATPase proteolipid family PsbJ PF01788.17 EAX98542.1 - 0.77 9.7 3.1 1.7 8.5 3.1 1.6 1 0 0 1 1 1 0 PsbJ DUF2179 PF10035.9 EAX98542.1 - 1.4 8.7 5.6 20 5.0 0.0 4.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2179) LRR_4 PF12799.7 EAX98542.1 - 1.9 9.0 14.3 7.9 7.1 1.2 4.9 3 3 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX98543.1 - 5.8e-30 103.9 2.3 5.8e-29 100.7 1.9 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98543.1 - 0.0092 15.7 0.1 0.095 12.5 0.1 2.5 2 1 2 4 4 4 2 Leucine rich repeat DUF4107 PF13389.6 EAX98544.1 - 6.7e-72 240.9 4.4 8.3e-72 240.6 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX98544.1 - 0.11 10.9 0.8 0.15 10.4 0.8 1.2 1 0 0 1 1 1 0 Lipoxygenase Amidase02_C PF12123.8 EAX98545.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX98547.1 - 3.6e-154 511.2 14.2 4.7e-154 510.8 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX98547.1 - 1.6 9.3 6.0 0.96 10.0 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX98547.1 - 2.5 8.6 7.0 2.1 8.8 0.4 3.3 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAX98548.1 - 0.00019 21.9 0.6 0.00052 20.5 0.3 1.9 2 1 0 2 2 2 1 T5orf172 domain Baculo_ME53 PF06061.11 EAX98548.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Trypan_PARP PF05887.11 EAX98549.1 - 0.028 14.4 7.5 0.043 13.8 7.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX98549.1 - 9.3 6.7 6.1 13 6.2 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAX98550.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Dimer_Tnp_hAT PF05699.14 EAX98551.1 - 0.057 13.2 1.0 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region DUF87 PF01935.17 EAX98551.1 - 0.063 13.4 1.3 0.24 11.5 1.3 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain Alba PF01918.21 EAX98551.1 - 0.18 11.6 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Alba TPR_20 PF14561.6 EAX98551.1 - 0.19 12.1 0.7 1.4 9.3 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat OSCP PF00213.18 EAX98553.1 - 0.0092 16.1 0.5 0.3 11.2 0.0 2.9 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit Cnd1 PF12717.7 EAX98553.1 - 0.0094 16.0 1.3 0.0094 16.0 1.3 5.5 4 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAX98553.1 - 0.03 14.7 0.1 1.5 9.2 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats ubiquitin PF00240.23 EAX98555.1 - 1.8e-09 37.2 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EAX98555.1 - 0.0013 19.1 0.0 0.0017 18.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAX98555.1 - 0.0062 16.4 0.0 0.028 14.3 0.0 1.8 1 1 1 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain UN_NPL4 PF11543.8 EAX98555.1 - 0.0083 16.6 0.0 0.019 15.4 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 ArgoL2 PF16488.5 EAX98555.1 - 0.018 15.4 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Argonaute linker 2 domain Rad60-SLD PF11976.8 EAX98555.1 - 0.036 13.9 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PhoLip_ATPase_C PF16212.5 EAX98556.1 - 1.2e-62 211.9 23.9 1.2e-62 211.9 23.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAX98556.1 - 3.1e-18 65.2 1.9 9.9e-18 63.6 1.9 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAX98556.1 - 3.3e-12 47.1 0.2 1e-09 39.0 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAX98556.1 - 1.8e-08 34.3 0.1 1.4e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EAX98556.1 - 3.8e-07 29.8 7.0 8.6e-07 28.7 0.2 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAX98556.1 - 0.032 14.0 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase UPF0449 PF15136.6 EAX98556.1 - 0.15 12.6 0.2 0.31 11.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 LSM PF01423.22 EAX98557.1 - 2.7e-13 49.4 0.0 4.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EAX98557.1 - 0.034 14.3 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain C2 PF00168.30 EAX98559.1 - 0.062 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 C2 domain CK_II_beta PF01214.18 EAX98560.1 - 1.4e-57 194.4 0.0 1.7e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p22 PF07426.11 EAX98563.1 - 0.00015 21.6 4.1 0.034 14.0 0.5 2.2 1 1 1 2 2 2 2 Dynactin subunit p22 His_Phos_2 PF00328.22 EAX98563.1 - 0.0092 15.4 0.3 0.0092 15.4 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NEMO PF11577.8 EAX98563.1 - 0.011 15.7 4.3 0.05 13.6 1.4 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO WXG100 PF06013.12 EAX98563.1 - 0.013 15.7 0.4 0.036 14.3 0.4 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG T3SSipB PF16535.5 EAX98563.1 - 0.015 15.8 0.4 0.018 15.5 0.4 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB GH97_N PF14508.6 EAX98563.1 - 0.019 14.5 0.4 0.019 14.5 0.4 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal ArAE_2_N PF10337.9 EAX98563.1 - 0.051 12.6 0.5 0.054 12.5 0.5 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal KxDL PF10241.9 EAX98563.1 - 0.059 13.7 1.9 0.14 12.4 1.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Pox_A_type_inc PF04508.12 EAX98563.1 - 0.097 12.6 4.7 1.1 9.2 0.8 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 EAX98563.1 - 0.11 12.6 3.9 0.13 12.5 3.9 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 EAX98563.1 - 0.18 11.7 5.7 0.34 10.7 5.7 1.4 1 1 0 1 1 1 0 CdvA-like coiled-coil domain DUF5344 PF17279.2 EAX98563.1 - 0.2 12.2 4.0 1.2 9.8 0.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5344) FapA PF03961.13 EAX98563.1 - 0.32 9.5 4.1 0.33 9.5 4.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A F5_F8_type_C PF00754.25 EAX98564.1 - 1.6e-07 31.4 2.9 2.9e-07 30.6 2.2 1.8 1 1 0 1 1 1 1 F5/8 type C domain Hom_end_hint PF05203.16 EAX98564.1 - 0.046 13.7 0.1 0.29 11.1 0.1 2.1 1 1 0 1 1 1 0 Hom_end-associated Hint DUF1413 PF07205.11 EAX98564.1 - 0.067 13.2 0.2 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) PriA_3primeBD PF17764.1 EAX98566.1 - 0.0055 16.6 0.1 0.063 13.2 0.0 2.5 3 0 0 3 3 3 1 3′ DNA-binding domain (3′BD) Methyltransf_10 PF05971.12 EAX98566.1 - 0.13 11.5 1.2 0.83 8.9 0.1 2.0 2 0 0 2 2 2 0 RNA methyltransferase Gly_rich PF12810.7 EAX98567.1 - 2.6e-07 30.8 28.4 3.5e-07 30.4 28.4 1.1 1 0 0 1 1 1 1 Glycine rich protein LBR_tudor PF09465.10 EAX98568.1 - 0.0032 17.2 0.1 0.0062 16.3 0.1 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Inhibitor_I69 PF13734.6 EAX98568.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Spi protease inhibitor PTR PF12789.7 EAX98569.1 - 8.4e-05 22.6 3.9 0.0035 17.4 0.6 5.5 4 2 1 5 5 5 2 Phage tail repeat like HIP1_clath_bdg PF16515.5 EAX98569.1 - 0.042 14.5 0.5 0.2 12.3 0.1 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rab5-bind PF09311.11 EAX98569.1 - 0.05 13.0 1.2 0.19 11.1 0.2 2.0 1 1 0 2 2 2 0 Rabaptin-like protein EpuA PF11772.8 EAX98569.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta LRR_5 PF13306.6 EAX98570.1 - 5.9e-45 152.3 13.4 7.8e-26 90.5 0.8 3.3 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98570.1 - 5.8e-12 45.2 2.4 0.0073 16.0 0.2 5.5 6 1 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAX98570.1 - 0.0056 17.1 9.9 1.2 9.6 0.0 5.1 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) Gly_rich PF12810.7 EAX98571.1 - 3e-28 99.4 31.3 3.3e-28 99.2 31.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX98572.1 - 7.5e-43 147.2 39.5 9.5e-43 146.8 39.5 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX98573.1 - 7.3e-14 51.8 4.2 2.6e-11 43.6 2.1 2.4 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF3963 PF13124.6 EAX98573.1 - 0.029 14.3 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) ACDC PF14733.6 EAX98573.1 - 0.059 13.7 1.9 0.074 13.4 0.1 2.1 2 1 1 3 3 3 0 AP2-coincident C-terminal Gly_rich PF12810.7 EAX98574.1 - 3.1e-48 164.8 20.2 1.5e-47 162.6 20.2 1.8 1 1 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX98575.1 - 8.9e-42 143.7 39.7 1.1e-41 143.4 39.7 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX98576.1 - 1.3e-24 86.6 9.0 1.1e-15 57.7 0.6 2.9 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98576.1 - 0.0018 18.0 0.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 EAX98577.1 - 5.9e-26 90.9 12.6 5.9e-13 48.9 5.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98577.1 - 0.012 15.3 0.0 1.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 EAX98577.1 - 0.095 13.2 2.4 27 5.4 0.0 4.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Pentapeptide_4 PF13599.6 EAX98577.1 - 0.12 12.5 0.6 0.75 10.0 0.5 2.3 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) LRR_5 PF13306.6 EAX98578.1 - 3.2e-82 272.8 48.9 3.5e-24 85.2 1.2 6.3 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98578.1 - 1.8e-20 72.4 5.1 0.0004 20.1 0.1 8.3 4 2 6 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 EAX98578.1 - 0.00026 21.3 14.7 1.2 9.6 0.8 7.0 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) Lipase_3 PF01764.25 EAX98579.1 - 4.4e-14 52.6 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EAX98579.1 - 0.0037 17.0 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EAX98579.1 - 0.0042 16.8 0.1 0.0059 16.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EAX98579.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EAX98579.1 - 0.045 13.0 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EAX98579.1 - 0.069 12.7 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.32 EAX98582.1 - 6.1e-38 128.2 18.8 3.2e-07 30.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX98582.1 - 5.9e-10 39.3 2.5 0.012 15.9 0.0 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX98582.1 - 0.00055 19.0 0.2 2.7 6.9 0.1 3.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAX98582.1 - 0.0019 18.1 0.5 0.021 14.7 0.1 2.5 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 EAX98582.1 - 0.047 14.2 1.0 20 5.8 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Nup160 PF11715.8 EAX98582.1 - 0.067 11.8 6.8 0.33 9.6 0.9 3.3 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Pox_A32 PF04665.12 EAX98583.1 - 3.6e-07 29.9 2.5 3.6e-07 29.9 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX98583.1 - 3.3e-05 24.2 0.2 0.00028 21.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX98583.1 - 4.2e-05 23.4 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX98583.1 - 0.00019 21.5 3.6 0.00045 20.3 3.7 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX98583.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX98583.1 - 0.0012 18.7 0.4 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX98583.1 - 0.0013 18.4 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX98583.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX98583.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX98583.1 - 0.091 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX98583.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX98583.1 - 0.38 11.0 4.0 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX98585.1 - 2.5e-63 212.3 5.7 2.8e-63 212.1 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3377 PF11857.8 EAX98587.1 - 0.0013 18.6 0.1 0.0029 17.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Syndecan PF01034.20 EAX98587.1 - 0.0022 17.9 3.0 0.0022 17.9 3.0 2.0 2 0 0 2 2 2 1 Syndecan domain AMA-1 PF02430.15 EAX98587.1 - 0.015 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Insulin_TMD PF17870.1 EAX98587.1 - 0.1 12.7 2.8 0.2 11.7 2.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MxiM PF11441.8 EAX98589.1 - 0.1 12.9 0.7 0.18 12.1 0.3 1.6 2 0 0 2 2 2 0 Pilot protein MxiM ThiF PF00899.21 EAX98592.1 - 2.6e-89 298.8 0.0 6.9e-61 205.7 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EAX98592.1 - 3.6e-55 187.6 9.4 6.1e-54 183.6 9.4 2.6 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EAX98592.1 - 6.1e-19 68.0 3.0 6.1e-19 68.0 3.0 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EAX98592.1 - 7.6e-08 33.0 0.9 7.6e-08 33.0 0.9 2.5 3 0 0 3 3 3 1 Ubiquitin fold domain E1_4HB PF16191.5 EAX98592.1 - 0.016 15.4 0.2 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle End_beta_barrel PF12195.8 EAX98592.1 - 0.05 13.6 1.7 0.073 13.0 0.3 1.9 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase Pkinase PF00069.25 EAX98593.1 - 2.2e-27 96.1 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98593.1 - 7.9e-17 61.4 0.0 1.6e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Med28 PF11594.8 EAX98595.1 - 0.079 13.0 0.2 0.16 12.1 0.2 1.6 1 1 0 1 1 1 0 Mediator complex subunit 28 Ank_2 PF12796.7 EAX98596.1 - 1.8e-25 89.3 2.1 1.1e-07 32.3 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98596.1 - 2.1e-23 82.4 0.4 2.6e-05 24.7 0.0 7.2 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98596.1 - 9.4e-18 62.5 7.5 0.62 10.8 0.1 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX98596.1 - 8.3e-16 57.9 5.4 0.017 15.5 0.0 7.6 4 2 4 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98596.1 - 5.3e-09 36.1 2.4 0.83 10.2 0.0 7.0 8 0 0 8 8 8 2 Ankyrin repeat EcoRII-C PF09019.11 EAX98596.1 - 0.13 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 EcoRII C terminal Beach PF02138.18 EAX98598.1 - 1.1e-107 359.6 0.1 2.5e-107 358.4 0.1 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAX98598.1 - 3.7e-09 36.6 1.0 1.2e-08 34.9 1.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH GRAM PF02893.20 EAX98598.1 - 3.4e-05 23.7 3.8 4.9e-05 23.2 1.1 2.8 2 0 0 2 2 2 1 GRAM domain DUF4800 PF16057.5 EAX98598.1 - 0.0012 18.2 1.0 0.0043 16.4 0.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 EAX98598.1 - 0.099 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Pox_polyA_pol_N PF12630.7 EAX98598.1 - 2.2 8.7 6.0 2.7 8.4 0.7 3.9 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain B56 PF01603.20 EAX98599.1 - 4.1e-112 375.2 7.0 4.1e-112 375.2 7.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 EAX98600.1 - 2.6e-60 204.0 0.0 3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98600.1 - 2.1e-37 128.8 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98600.1 - 6.7e-07 28.9 0.0 2.1e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX98600.1 - 1.3e-06 27.5 0.0 2.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EAX98600.1 - 9.7e-06 24.8 0.1 1.8e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX98600.1 - 0.00042 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX98600.1 - 0.0027 17.3 0.2 0.0056 16.3 0.2 1.5 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EAX98600.1 - 0.0085 15.6 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EAX98600.1 - 0.027 14.4 0.5 0.058 13.3 0.5 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAX98600.1 - 0.043 13.4 0.6 0.23 11.0 0.3 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RTP PF02334.16 EAX98600.1 - 0.058 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Replication terminator protein DUF2905 PF11146.8 EAX98600.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Ras PF00071.22 EAX98601.1 - 3.7e-48 163.2 0.5 4.4e-48 162.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX98601.1 - 1.4e-33 115.7 0.1 2.2e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX98601.1 - 9.4e-17 61.0 0.3 1.1e-16 60.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX98601.1 - 8.7e-06 25.8 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX98601.1 - 2.7e-05 23.7 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX98601.1 - 0.00029 20.3 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EAX98601.1 - 0.0015 18.3 0.4 0.01 15.6 0.3 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 EAX98601.1 - 0.0047 16.4 0.1 0.093 12.1 0.0 2.4 2 1 1 3 3 3 1 Bacterial TniB protein AAA_14 PF13173.6 EAX98601.1 - 0.0058 16.7 1.0 0.018 15.1 0.1 2.0 1 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAX98601.1 - 0.0075 16.2 0.2 1 9.3 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX98601.1 - 0.012 15.2 0.3 0.027 14.0 0.2 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EAX98601.1 - 0.012 15.9 0.0 0.24 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sld7_N PF18636.1 EAX98601.1 - 0.023 15.0 0.1 0.052 13.9 0.0 1.6 1 1 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain PduV-EutP PF10662.9 EAX98601.1 - 0.048 13.4 0.2 0.1 12.4 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAX98601.1 - 0.19 12.1 0.0 0.84 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF2530 PF10745.9 EAX98602.1 - 0.79 10.0 2.6 7.7 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Peptidase_M8 PF01457.16 EAX98603.1 - 2.2e-16 59.7 0.7 4.3e-16 58.7 0.7 1.4 1 0 0 1 1 1 1 Leishmanolysin TMEM154 PF15102.6 EAX98603.1 - 0.0017 18.3 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 TMEM154 protein family PRIMA1 PF16101.5 EAX98603.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 PSP PF04046.16 EAX98604.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98605.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX98607.1 - 2.3e-24 85.2 12.5 2.3e-24 85.2 12.5 4.1 5 1 1 6 6 6 1 Phage tail repeat like DUF3839 PF12943.7 EAX98609.1 - 1.1e-157 522.7 13.1 1.4e-157 522.4 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX98609.1 - 0.11 12.9 0.3 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX98609.1 - 0.9 10.0 5.2 7.3 7.1 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.12 EAX98610.1 - 0.0065 16.9 9.1 0.0065 16.9 9.1 48.2 9 6 24 33 33 33 1 Cell division protein ZapB DUF167 PF02594.16 EAX98610.1 - 0.32 11.1 34.9 8.9 6.5 0.2 8.8 8 0 0 8 8 8 0 Uncharacterised ACR, YggU family COG1872 Pkinase PF00069.25 EAX98611.1 - 9.6e-64 215.3 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98611.1 - 9.1e-42 143.1 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX98611.1 - 8e-06 25.0 0.1 1.4e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAX98611.1 - 1.2e-05 24.8 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAX98611.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 EAX98612.1 - 1.2e-29 102.3 1.6 1.1e-14 54.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98612.1 - 2.4e-19 69.3 0.0 2.7e-08 33.9 0.1 2.2 1 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX98612.1 - 8.4e-05 22.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EAX98612.1 - 9.1e-05 22.5 0.1 0.061 13.4 0.2 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EAX98612.1 - 0.00036 20.5 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX98612.1 - 0.035 14.3 1.3 3.6 7.8 0.0 2.9 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EAX98612.1 - 3.8 8.0 6.2 21 5.6 0.7 3.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 EAX98613.1 - 8.6e-47 157.6 0.4 8e-12 45.6 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98613.1 - 3e-37 126.5 1.8 5.4e-09 36.4 0.0 7.6 4 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98613.1 - 1.8e-36 120.0 5.2 0.0018 18.6 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAX98613.1 - 1.5e-28 98.4 1.2 0.00034 20.9 0.0 7.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX98613.1 - 1e-27 95.3 5.0 0.00065 20.0 0.1 9.3 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 EAX98613.1 - 0.0082 16.1 5.8 1.3 9.0 0.1 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) VWA PF00092.28 EAX98613.1 - 0.013 15.8 0.8 0.029 14.6 0.8 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Myb_DNA-bind_3 PF12776.7 EAX98613.1 - 0.074 14.0 5.2 0.39 11.7 0.1 2.9 2 1 1 3 3 2 0 Myb/SANT-like DNA-binding domain Chordopox_A30L PF06015.12 EAX98613.1 - 0.34 10.8 5.4 0.86 9.5 5.4 1.6 1 0 0 1 1 1 0 Chordopoxvirus A30L protein VWA_2 PF13519.6 EAX98613.1 - 1.4 9.6 3.6 1 10.0 0.3 2.5 3 0 0 3 3 3 0 von Willebrand factor type A domain DUF2935 PF11155.8 EAX98613.1 - 1.9 8.9 5.2 31 4.9 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) HalX PF08663.10 EAX98613.1 - 2.5 8.5 7.1 11 6.4 0.1 3.1 3 0 0 3 3 3 0 HalX domain TPR_MLP1_2 PF07926.12 EAX98613.1 - 5.6 7.0 26.4 6.5 6.8 6.3 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 EAX98613.1 - 6.2 7.0 15.1 1.3 9.2 2.5 3.8 3 1 1 4 4 4 0 Intraflagellar transport complex B, subunit 20 PQ-loop PF04193.14 EAX98614.1 - 6.8e-21 73.8 7.2 6.7e-13 48.2 0.4 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EAX98614.1 - 0.12 13.2 8.6 0.18 12.6 3.8 2.6 1 1 2 3 3 3 0 ER lumen protein retaining receptor Ribosomal_L37e PF01907.19 EAX98615.1 - 2.8e-25 88.2 9.4 3.9e-25 87.8 9.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 EAX98615.1 - 0.089 12.8 2.3 0.14 12.2 2.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 EAX98615.1 - 2.2 7.8 6.6 10 5.7 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Synaptobrevin PF00957.21 EAX98616.1 - 4e-05 23.3 3.6 6.7e-05 22.6 3.6 1.4 1 0 0 1 1 1 1 Synaptobrevin ArnB_C PF18677.1 EAX98616.1 - 2.2 8.4 5.1 6.3 7.0 2.8 2.7 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Pkinase PF00069.25 EAX98617.1 - 5.3e-53 180.1 0.0 8.8e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98617.1 - 8.7e-25 87.5 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX98617.1 - 5.4e-07 29.2 0.2 9e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX98617.1 - 1.5e-05 25.1 0.1 2.4e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAX98617.1 - 5e-05 22.4 0.1 8.5e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX98617.1 - 5.7e-05 22.1 0.1 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAX98617.1 - 0.00038 20.1 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAX98617.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EAX98617.1 - 0.046 12.7 0.3 0.076 12.0 0.3 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 EAX98617.1 - 0.086 12.4 0.6 0.15 11.6 0.6 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase LCAT PF02450.15 EAX98618.1 - 6.9e-26 91.3 1.3 8.3e-26 91.1 0.3 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EAX98618.1 - 0.0074 16.9 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EAX98618.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 EAX98618.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 EAX98618.1 - 0.028 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 EAX98618.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX98618.1 - 0.051 12.8 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 EAX98619.1 - 1.3e-16 60.8 0.0 1.5e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAX98619.1 - 5.7e-06 26.4 0.0 5.7e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAX98619.1 - 8.8e-05 21.9 0.1 9.2e-05 21.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX98619.1 - 0.00019 20.8 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAX98619.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EAX98619.1 - 0.04 13.5 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase B56 PF01603.20 EAX98620.1 - 7.5e-12 44.9 0.2 7.5e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sel1 PF08238.12 EAX98620.1 - 2.9e-05 24.6 2.4 2 9.2 0.3 4.4 4 0 0 4 4 4 2 Sel1 repeat Cnd1 PF12717.7 EAX98621.1 - 1.7 8.6 5.7 3.4 7.7 0.6 3.4 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Myb_DNA-binding PF00249.31 EAX98622.1 - 1.5e-40 137.1 9.7 4.6e-16 58.7 1.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98622.1 - 3.6e-35 120.0 4.2 7e-14 51.8 0.0 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98622.1 - 1e-06 28.8 0.3 0.15 12.1 0.2 3.4 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX98622.1 - 1.4e-05 24.9 6.4 0.003 17.4 0.7 3.7 1 1 3 4 4 4 2 Myb DNA-binding like Rap1_C PF11626.8 EAX98622.1 - 3e-05 24.0 1.3 0.92 9.6 0.4 3.2 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAX98622.1 - 0.00052 20.1 1.2 0.29 11.3 0.2 3.9 2 1 1 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAX98622.1 - 0.002 18.3 2.4 0.31 11.3 0.1 3.3 2 1 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Atg29_N PF18388.1 EAX98622.1 - 0.15 11.9 3.0 18 5.3 0.1 3.4 3 0 0 3 3 3 0 Atg29 N-terminal domain DUF1348 PF07080.11 EAX98622.1 - 0.59 10.1 3.8 0.42 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) GCN5L1 PF06320.13 EAX98624.1 - 0.0051 16.9 1.5 0.011 15.8 1.5 1.6 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1722 PF08349.11 EAX98624.1 - 0.013 15.8 1.0 0.1 12.9 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1722) ATP-synt_E PF05680.12 EAX98624.1 - 0.014 15.8 0.2 0.03 14.7 0.2 1.5 1 0 0 1 1 1 0 ATP synthase E chain Bromodomain PF00439.25 EAX98624.1 - 0.021 14.9 4.3 0.038 14.0 0.4 2.5 1 1 1 2 2 2 0 Bromodomain Oxidored_nitro PF00148.19 EAX98624.1 - 0.21 10.3 0.1 1.9 7.1 0.0 1.9 1 1 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase SapB_1 PF05184.15 EAX98624.1 - 0.47 10.5 4.8 28 4.9 0.1 3.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 EF-hand_6 PF13405.6 EAX98625.1 - 9.3e-05 22.1 0.4 0.00044 20.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain ANAPC4_WD40 PF12894.7 EAX98625.1 - 0.0005 20.3 0.8 6.6 7.1 0.0 4.7 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 EAX98625.1 - 0.00058 19.2 0.1 0.0015 17.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EAX98625.1 - 0.0007 19.0 0.1 0.0023 17.3 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EAX98625.1 - 0.013 16.0 1.5 0.026 15.0 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 EAX98625.1 - 0.026 14.4 0.1 0.067 13.0 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair BBS1 PF14779.6 EAX98625.1 - 0.058 12.8 0.2 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 GUB_WAK_bind PF13947.6 EAX98625.1 - 1.2 9.9 3.8 11 6.8 0.0 3.1 3 0 0 3 3 3 0 Wall-associated receptor kinase galacturonan-binding Pox_A32 PF04665.12 EAX98626.1 - 6.6e-05 22.5 2.5 7.9e-05 22.2 1.5 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX98626.1 - 0.0055 16.7 0.8 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX98626.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ARA70 PF12489.8 EAX98627.1 - 0.1 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Nuclear coactivator ADIP PF11559.8 EAX98628.1 - 0.013 15.6 22.3 0.013 15.6 22.3 7.2 4 1 3 7 7 7 0 Afadin- and alpha -actinin-Binding Beta_helix PF13229.6 EAX98629.1 - 0.17 11.7 8.2 0.3 10.9 8.2 1.4 1 0 0 1 1 1 0 Right handed beta helix region Ank_2 PF12796.7 EAX98630.1 - 9.9e-62 205.5 10.1 3e-13 50.2 0.0 8.3 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98630.1 - 4e-52 173.9 6.4 3.9e-13 49.6 0.0 10.9 5 3 6 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98630.1 - 9e-50 166.1 11.3 8.6e-11 41.9 0.0 11.8 5 5 8 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98630.1 - 1.3e-46 151.1 16.2 3.9e-07 29.9 0.0 13.6 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 EAX98630.1 - 2.9e-41 138.1 7.5 1.9e-06 28.0 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat DUF3447 PF11929.8 EAX98630.1 - 2e-05 24.5 12.9 0.00012 22.0 0.3 5.3 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) SwrA PF17423.2 EAX98630.1 - 0.18 11.8 4.5 0.37 10.8 0.5 3.3 4 1 0 4 4 4 0 Swarming motility protein Ras PF00071.22 EAX98632.1 - 2e-34 118.5 0.0 2.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX98632.1 - 1.6e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX98632.1 - 1e-06 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EAX98632.1 - 1.3e-05 24.7 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX98632.1 - 0.0003 20.7 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAX98632.1 - 0.0033 17.8 0.0 0.0049 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAX98632.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAX98632.1 - 0.0081 16.4 0.1 0.11 12.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 EAX98632.1 - 0.016 14.8 0.1 0.027 14.0 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.14 EAX98632.1 - 0.018 15.1 0.1 0.043 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EAX98632.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 EAX98632.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EAX98632.1 - 0.11 12.2 0.6 0.29 10.8 0.0 2.0 3 1 0 3 3 3 0 AAA domain SRPRB PF09439.10 EAX98632.1 - 0.17 11.3 0.0 1.2 8.6 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAX98632.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1601 PF07671.11 EAX98633.1 - 0.2 11.5 2.1 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) DUF1647 PF07801.11 EAX98635.1 - 0.05 13.4 1.3 0.061 13.1 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) V-SNARE PF05008.15 EAX98635.1 - 0.06 13.7 0.3 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.12 EAX98635.1 - 0.4 10.7 5.4 0.12 12.4 2.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2_4 PF13894.6 EAX98636.1 - 7.1e-06 26.4 14.9 0.064 14.1 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX98636.1 - 8.8e-06 25.9 12.7 0.0026 18.1 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 EAX98636.1 - 0.0068 16.8 9.5 0.13 12.7 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EAX98636.1 - 0.01 15.7 4.6 0.56 10.1 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 EAX98636.1 - 0.019 15.3 7.8 2.2 8.7 0.1 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 EAX98636.1 - 0.022 15.2 1.8 0.022 15.2 1.8 2.7 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 EAX98636.1 - 0.038 14.3 1.2 0.038 14.3 1.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding YdjO PF14169.6 EAX98636.1 - 0.045 13.5 0.6 3.5 7.4 0.0 3.2 3 0 0 3 3 3 0 Cold-inducible protein YdjO DUF468 PF04318.12 EAX98636.1 - 0.052 14.3 0.7 0.097 13.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF468) zf-C2H2_3rep PF18868.1 EAX98636.1 - 0.11 13.1 8.0 34 5.1 0.0 3.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ephrin_rec_like PF07699.13 EAX98636.1 - 0.12 12.2 5.6 0.19 11.5 0.3 2.9 3 0 0 3 3 3 0 Putative ephrin-receptor like zf-Di19 PF05605.12 EAX98636.1 - 0.17 12.2 10.3 2.7 8.3 3.9 3.2 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding YebO PF13974.6 EAX98636.1 - 0.2 11.7 1.2 0.48 10.5 1.2 1.6 1 0 0 1 1 1 0 YebO-like protein DZR PF12773.7 EAX98636.1 - 0.23 11.5 4.4 0.27 11.3 0.2 2.8 3 0 0 3 3 3 0 Double zinc ribbon zf-BED PF02892.15 EAX98636.1 - 0.55 10.3 9.2 0.12 12.4 1.7 2.9 3 0 0 3 3 3 0 BED zinc finger zinc_ribbon_15 PF17032.5 EAX98636.1 - 0.68 10.7 4.7 0.67 10.7 0.4 2.7 2 1 1 3 3 3 0 zinc-ribbon family ADK_lid PF05191.14 EAX98636.1 - 1.5 8.9 6.8 3.8 7.6 0.2 3.2 3 1 0 3 3 3 0 Adenylate kinase, active site lid FOXP-CC PF16159.5 EAX98636.1 - 1.5 9.5 8.2 1.7 9.3 0.6 3.0 3 1 0 3 3 2 0 FOXP coiled-coil domain zinc-ribbons_6 PF07191.12 EAX98636.1 - 1.9 8.6 6.0 1.7 8.7 0.8 2.7 3 0 0 3 3 3 0 zinc-ribbons zf-H2C2_2 PF13465.6 EAX98636.1 - 2.2 8.9 7.8 20 5.8 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger double domain SNARE PF05739.19 EAX98639.1 - 9.3e-13 48.0 0.3 9.3e-13 48.0 0.3 1.7 2 0 0 2 2 2 1 SNARE domain DUF2951 PF11166.8 EAX98639.1 - 0.00024 21.2 0.7 0.00031 20.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) Prominin PF05478.11 EAX98639.1 - 0.00045 18.3 0.3 0.0005 18.2 0.3 1.0 1 0 0 1 1 1 1 Prominin Syntaxin PF00804.25 EAX98639.1 - 0.021 14.5 1.7 0.021 14.5 1.7 1.7 2 0 0 2 2 2 0 Syntaxin Polysacc_synt PF01943.17 EAX98639.1 - 0.028 13.8 0.1 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MAT1 PF06391.13 EAX98639.1 - 0.031 14.1 1.4 0.035 13.9 1.4 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Use1 PF09753.9 EAX98639.1 - 0.032 14.0 2.4 0.035 13.8 2.4 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Histone_HNS PF00816.21 EAX98639.1 - 0.064 14.1 1.0 0.086 13.7 1.0 1.1 1 0 0 1 1 1 0 H-NS histone family SLATT_5 PF18160.1 EAX98639.1 - 0.067 12.5 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Neurensin PF14927.6 EAX98639.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Neurensin DUF2895 PF11444.8 EAX98639.1 - 1.3 8.3 3.9 0.38 10.1 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2895) DUF563 PF04577.14 EAX98640.1 - 4.6e-31 108.6 0.1 6.9e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Toxin_R_bind_C PF07951.12 EAX98641.1 - 0.012 15.2 2.7 0.073 12.7 0.4 2.5 2 1 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding Herpes_IE2_3 PF03361.14 EAX98641.1 - 0.042 13.7 1.2 0.96 9.3 0.3 2.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAX98641.1 - 0.77 10.1 8.2 2.3 8.6 0.7 3.0 3 0 0 3 3 3 0 PPP5 TPR repeat region Bromodomain PF00439.25 EAX98642.1 - 0.00022 21.2 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 EAX98643.1 - 5.1e-54 183.4 0.0 7.9e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98643.1 - 1.4e-31 109.7 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98643.1 - 1.4e-06 27.8 0.0 6.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX98643.1 - 0.026 13.9 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX98643.1 - 0.052 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98643.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EAX98643.1 - 0.18 10.7 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Npa1 PF11707.8 EAX98644.1 - 0.003 17.0 1.1 0.19 11.1 0.0 2.7 2 1 0 2 2 2 2 Ribosome 60S biogenesis N-terminal DUF846 PF05832.12 EAX98645.1 - 2.3e-37 128.1 12.9 3.1e-37 127.7 12.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_desaturase PF00487.24 EAX98645.1 - 6.6 6.5 9.7 0.58 9.9 3.5 2.0 1 1 2 3 3 3 0 Fatty acid desaturase Proteasome PF00227.26 EAX98646.1 - 4e-38 130.8 0.0 4.6e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4174 PF13778.6 EAX98646.1 - 0.017 15.6 0.1 5 7.6 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) EF-hand_1 PF00036.32 EAX98647.1 - 2.2e-24 83.1 5.3 1.7e-05 24.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX98647.1 - 1.2e-22 80.2 6.3 8.1e-12 45.4 0.6 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EAX98647.1 - 2.8e-21 75.1 7.4 0.00011 22.0 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAX98647.1 - 2.1e-20 71.2 0.5 0.00044 19.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAX98647.1 - 3.6e-19 67.0 5.9 0.0012 18.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_4 PF12763.7 EAX98647.1 - 2.4e-07 30.7 4.0 0.021 14.8 0.1 3.0 1 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAX98647.1 - 6.5e-06 26.4 0.6 0.092 13.1 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EAX98647.1 - 0.00048 20.4 0.1 0.66 10.3 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain RasGAP_C PF03836.15 EAX98647.1 - 0.034 14.3 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 RasGAP C-terminus EF-hand_10 PF14788.6 EAX98647.1 - 0.048 13.5 2.7 2.1 8.3 0.2 3.5 2 1 2 4 4 4 0 EF hand LRR_5 PF13306.6 EAX98649.1 - 1.5e-81 270.6 90.3 6.5e-20 71.4 18.3 7.9 1 1 5 7 7 7 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98649.1 - 1.1e-08 34.7 28.4 0.52 10.1 0.0 11.9 8 5 5 14 14 14 4 Leucine rich repeat Glycophorin_A PF01102.18 EAX98649.1 - 0.088 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Herpes_gI PF01688.17 EAX98649.1 - 0.37 10.7 5.6 22 4.9 0.0 5.2 5 1 1 6 6 6 0 Alphaherpesvirus glycoprotein I LRR_5 PF13306.6 EAX98650.1 - 1.9e-133 438.5 72.6 2.5e-31 108.3 13.6 6.1 2 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98650.1 - 3e-24 84.5 0.0 0.0043 16.8 0.0 8.8 7 2 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EAX98650.1 - 6.7e-09 35.9 0.1 0.58 10.7 0.0 7.7 7 2 1 8 8 8 2 Leucine Rich repeats (2 copies) CAP PF00188.26 EAX98651.1 - 0.037 14.8 0.8 0.037 14.8 0.8 2.2 1 1 1 2 2 2 0 Cysteine-rich secretory protein family Chlam_PMP PF02415.17 EAX98651.1 - 0.24 12.0 0.3 0.24 12.0 0.3 3.8 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SNAP PF14938.6 EAX98652.1 - 1.2e-66 225.0 12.9 1.4e-66 224.8 12.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 EAX98652.1 - 1.6e-05 24.5 0.6 2.1e-05 24.1 0.6 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 EAX98652.1 - 0.00014 22.1 9.5 0.098 13.0 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAX98652.1 - 0.00032 21.3 0.8 0.18 12.5 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAX98652.1 - 0.00046 20.1 17.7 0.19 11.9 0.4 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX98652.1 - 0.00069 19.2 6.1 0.92 9.2 0.1 4.6 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 EAX98652.1 - 0.0077 16.2 2.8 8.1 6.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAX98652.1 - 0.058 13.4 1.4 0.14 12.1 0.3 2.2 1 1 0 2 2 2 0 Putative TPR-like repeat TPR_1 PF00515.28 EAX98652.1 - 0.3 11.0 21.5 0.23 11.3 1.4 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 EAX98652.1 - 2.5 8.3 17.5 0.072 13.2 1.3 4.9 5 2 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EAX98652.1 - 4.1 7.9 18.4 4.1 7.9 0.7 5.0 6 1 1 7 7 6 0 Tetratricopeptide repeat Beta_helix PF13229.6 EAX98653.1 - 1.4e-06 28.3 6.5 4.5e-06 26.6 6.3 1.9 1 1 0 1 1 1 1 Right handed beta helix region Pentapeptide_4 PF13599.6 EAX98653.1 - 4.5 7.5 15.9 6 7.1 9.0 3.9 3 2 0 3 3 3 0 Pentapeptide repeats (9 copies) Importin_rep_2 PF18786.1 EAX98654.1 - 0.057 13.3 0.2 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat TFIIA PF03153.13 EAX98655.1 - 0.33 10.9 27.4 0.47 10.4 27.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DinI PF06183.13 EAX98656.1 - 0.17 12.2 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 DinI-like family Ank PF00023.30 EAX98657.1 - 2.3e-22 78.4 1.8 5.3e-08 33.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EAX98657.1 - 5.5e-19 68.3 0.3 2.5e-09 37.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98657.1 - 2.1e-18 66.7 0.5 2.8e-18 66.3 0.5 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98657.1 - 7.5e-18 62.8 0.7 3.4e-06 27.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX98657.1 - 1.7e-09 37.7 1.3 5.7e-07 29.7 0.4 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2520 PF10728.9 EAX98657.1 - 0.03 14.1 0.2 4.9 6.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) MOEP19 PF16005.5 EAX98657.1 - 0.056 13.5 0.0 9 6.4 0.0 2.1 1 1 1 2 2 2 0 KH-like RNA-binding domain Ribosomal_S6 PF01250.17 EAX98657.1 - 0.12 12.7 0.1 14 6.1 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S6 DUF3447 PF11929.8 EAX98658.1 - 1.1e-38 131.1 6.0 1.1e-38 131.1 6.0 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98658.1 - 1.2e-34 118.2 9.3 7.3e-10 39.2 0.0 6.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX98658.1 - 4.7e-33 112.2 5.7 1.3e-06 28.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 EAX98658.1 - 5.2e-33 113.5 12.9 7.5e-14 52.1 2.4 3.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98658.1 - 4.8e-26 88.0 12.3 0.0001 22.4 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX98658.1 - 3.4e-18 65.5 3.1 1.7e-07 31.3 0.3 5.0 3 2 3 6 6 6 3 Ankyrin repeats (many copies) RNase_PH_C PF03725.15 EAX98658.1 - 0.0033 17.4 0.5 7.3 6.7 0.0 3.9 1 1 3 4 4 4 1 3' exoribonuclease family, domain 2 BRCT_2 PF16589.5 EAX98658.1 - 0.09 13.2 1.5 35 4.9 0.0 3.4 1 1 2 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain ELMO_CED12 PF04727.13 EAX98658.1 - 1.1 9.3 3.5 1.4 9.0 0.9 2.4 3 1 0 3 3 3 0 ELMO/CED-12 family LisH_TPL PF17814.1 EAX98659.1 - 0.0048 16.5 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain Spt20 PF12090.8 EAX98660.1 - 3.1e-24 85.9 4.6 1.1e-15 57.9 0.1 2.9 2 1 1 3 3 3 2 Spt20 family F5_F8_type_C PF00754.25 EAX98662.1 - 0.00013 22.1 3.1 0.00013 22.1 3.1 2.5 3 0 0 3 3 3 1 F5/8 type C domain Ndc1_Nup PF09531.10 EAX98662.1 - 0.013 14.2 7.2 0.02 13.6 7.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 EAX98662.1 - 0.015 15.3 7.0 0.031 14.3 7.0 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BACK PF07707.15 EAX98662.1 - 0.06 13.4 0.0 0.46 10.6 0.0 2.4 1 1 1 2 2 2 0 BTB And C-terminal Kelch SpoIIIAH PF12685.7 EAX98662.1 - 0.5 10.1 18.6 0.19 11.5 16.1 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein Neur_chan_memb PF02932.16 EAX98662.1 - 0.81 9.7 5.6 1.3 9.0 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EAX98662.1 - 1.3 9.0 24.8 2 8.3 24.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EAX98662.1 - 5.3 5.7 14.1 8.2 5.1 14.1 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 EAX98662.1 - 7 4.8 23.7 10 4.3 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 C2 PF00168.30 EAX98663.1 - 1.5e-28 99.0 0.1 2.8e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 C2 domain Peptidase_M24 PF00557.24 EAX98664.1 - 4.8e-51 173.4 0.0 6.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAX98664.1 - 1.8e-19 69.7 0.0 3.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RTT107_BRCT_6 PF16771.5 EAX98664.1 - 0.028 14.6 0.3 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Gly-zipper_Omp PF13488.6 EAX98667.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX98667.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX98667.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Peptidase_S41_N PF11918.8 EAX98669.1 - 0.11 12.7 0.9 0.59 10.4 0.4 2.3 2 1 1 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Bromo_TP_like PF17027.5 EAX98669.1 - 1.8 8.7 17.5 0.063 13.4 6.0 3.1 3 0 0 3 3 3 0 Histone-fold protein MULE PF10551.9 EAX98670.1 - 2.3e-10 40.8 0.2 4.6e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAX98670.1 - 0.047 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase FAR1 PF03101.15 EAX98670.1 - 0.051 14.3 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain PQQ PF01011.21 EAX98673.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat DUF948 PF06103.11 EAX98676.1 - 0.12 12.7 2.5 0.22 11.8 1.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CDK2AP PF09806.9 EAX98676.1 - 0.5 10.4 8.4 0.76 9.8 7.2 1.9 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Raptor_N PF14538.6 EAX98677.1 - 2.4e-30 105.4 0.6 7e-30 103.9 0.6 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 EAX98677.1 - 0.00024 21.4 0.0 0.54 10.7 0.0 3.0 2 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EAX98677.1 - 0.00091 19.3 0.5 9.7 6.8 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat DUF4221 PF13970.6 EAX98677.1 - 0.0044 16.6 0.5 0.0088 15.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) Cnd1 PF12717.7 EAX98677.1 - 0.69 9.9 6.6 1.8 8.5 0.7 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UCH PF00443.29 EAX98678.1 - 1.7e-28 99.8 0.0 1.3e-27 96.9 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX98678.1 - 6.5e-05 22.7 2.3 0.00053 19.7 0.1 2.4 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Retrotrans_gag PF03732.17 EAX98679.1 - 0.048 13.9 0.2 0.52 10.6 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3870 PF12986.7 EAX98679.1 - 0.087 13.1 0.3 0.15 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Snf7 PF03357.21 EAX98680.1 - 1.1e-08 34.9 6.9 1.2e-08 34.8 6.9 1.1 1 0 0 1 1 1 1 Snf7 Pox_polyA_pol_C PF12629.7 EAX98680.1 - 0.0083 16.0 3.7 0.056 13.3 3.7 1.9 1 1 0 1 1 1 1 Poxvirus poly(A) polymerase C-terminal domain ABC_tran PF00005.27 EAX98681.1 - 7.8e-11 42.6 0.2 1.4e-10 41.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAX98681.1 - 0.0057 16.5 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EAX98681.1 - 0.0078 16.4 0.0 0.58 10.4 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EAX98682.1 - 1.3e-31 109.9 0.0 2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX98682.1 - 1.3e-11 44.9 1.3 0.0001 22.2 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX98682.1 - 1.6e-06 27.8 0.1 3.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX98682.1 - 2.2e-06 27.3 0.7 0.0024 17.3 0.2 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAX98682.1 - 4.6e-05 24.0 0.0 9.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX98682.1 - 0.00011 22.7 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EAX98682.1 - 0.0015 18.3 1.0 0.0022 17.8 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAX98682.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EAX98682.1 - 0.0079 16.3 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EAX98682.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EAX98682.1 - 0.019 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EAX98682.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EAX98682.1 - 0.025 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ABC_ATPase PF09818.9 EAX98682.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_27 PF13514.6 EAX98682.1 - 0.032 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAX98682.1 - 0.043 14.2 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 EAX98682.1 - 0.051 13.9 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAX98682.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EAX98682.1 - 0.09 12.5 0.0 1 9.1 0.0 2.2 1 1 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EAX98682.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EAX98682.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 EAX98682.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase SbcCD_C PF13558.6 EAX98682.1 - 0.11 12.7 0.0 1.9 8.8 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EAX98682.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAX98682.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EAX98682.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAX98682.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.25 EAX98683.1 - 3.7e-06 27.1 0.1 3.2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain PUA_2 PF14306.6 EAX98683.1 - 0.13 11.9 0.9 0.56 9.9 0.2 1.9 2 0 0 2 2 2 0 PUA-like domain LysE PF01810.18 EAX98684.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 LysE type translocator GCR PF02155.15 EAX98685.1 - 0.00055 19.1 2.5 0.00055 19.1 2.5 1.9 1 1 1 2 2 2 1 Glucocorticoid receptor gpW PF02831.15 EAX98685.1 - 0.014 15.3 3.4 1.2 9.0 0.1 3.8 3 1 1 4 4 4 0 gpW DivIC PF04977.15 EAX98685.1 - 0.014 15.1 6.7 0.014 15.1 6.7 4.6 2 1 3 5 5 5 0 Septum formation initiator Prefoldin_2 PF01920.20 EAX98685.1 - 0.029 14.3 1.0 0.029 14.3 1.0 4.5 2 1 1 4 4 4 0 Prefoldin subunit SlyX PF04102.12 EAX98685.1 - 0.045 14.4 2.7 0.045 14.4 2.7 4.3 1 1 3 4 4 4 0 SlyX DUF2023 PF09633.10 EAX98685.1 - 0.56 10.4 4.0 0.26 11.4 0.3 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2023) DUF3293 PF11697.8 EAX98685.1 - 4.1 8.0 6.2 1.5 9.4 0.6 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3293) APG6_N PF17675.1 EAX98685.1 - 4.3 7.9 38.6 0.35 11.4 9.9 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF4618 PF15397.6 EAX98685.1 - 5.1 6.4 29.4 0.6 9.5 12.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Suppressor_APC PF11414.8 EAX98685.1 - 5.1 7.2 17.8 0.54 10.4 0.5 3.3 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Swi5 PF07061.11 EAX98685.1 - 5.9 7.1 28.4 0.99 9.5 5.4 4.5 3 2 1 4 4 4 0 Swi5 AAA_13 PF13166.6 EAX98685.1 - 8.1 4.9 33.7 3.6e+03 -3.8 33.7 2.4 1 1 0 1 1 1 0 AAA domain HalX PF08663.10 EAX98685.1 - 9 6.7 15.5 5.7 7.3 2.1 4.1 4 1 0 4 4 4 0 HalX domain 2-Hacid_dh_C PF02826.19 EAX98686.1 - 1e-41 142.3 0.0 1.6e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAX98686.1 - 5.9e-32 110.1 0.0 1.4e-31 108.9 0.0 1.7 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAX98686.1 - 4.1e-06 27.0 0.3 4.1e-06 27.0 0.3 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAX98686.1 - 0.00043 20.8 1.9 0.0043 17.6 0.1 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TMP PF05017.14 EAX98687.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat LRR_5 PF13306.6 EAX98689.1 - 3.1e-41 140.3 32.0 4.3e-19 68.7 7.7 3.9 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98689.1 - 0.0017 18.1 0.0 3.2 7.6 0.0 3.0 2 1 0 2 2 2 2 Leucine rich repeat AftA_N PF12250.8 EAX98689.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal LRR_5 PF13306.6 EAX98690.1 - 2.6e-191 625.5 53.1 6.3e-31 107.0 0.9 7.1 2 2 6 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98690.1 - 3.6e-07 29.8 10.7 3.6 7.4 0.0 8.8 8 2 3 11 11 11 4 Leucine rich repeat Chalcone_N PF18232.1 EAX98690.1 - 0.2 12.1 2.3 2.6 8.5 0.0 3.7 3 1 1 4 4 4 0 Chalcone isomerase N-terminal domain LRR_5 PF13306.6 EAX98691.1 - 9.7e-128 420.0 76.6 1.6e-22 79.8 8.6 5.5 1 1 7 8 8 8 8 BspA type Leucine rich repeat region (6 copies) Hexapep PF00132.24 EAX98691.1 - 0.16 11.7 1.0 4.9 7.0 0.0 3.6 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) NDUF_B7 PF05676.13 EAX98691.1 - 0.32 10.8 2.7 4.1 7.2 0.1 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_4 PF13637.6 EAX98692.1 - 6.4e-20 71.3 0.5 6.9e-13 48.8 0.1 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98692.1 - 2.6e-14 53.1 0.5 1.8e-09 37.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98692.1 - 4.3e-13 48.2 0.4 3.8e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX98692.1 - 1.8e-12 47.6 0.1 4e-12 46.6 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98692.1 - 3.9e-12 46.0 0.2 6e-05 23.3 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX98693.1 - 1e-08 34.7 0.4 0.0051 17.2 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX98693.1 - 1.6e-08 35.0 0.3 2.8e-08 34.2 0.3 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98693.1 - 1.6e-08 34.6 1.8 2.7e-05 24.4 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX98693.1 - 3.6e-08 33.8 0.1 4.6e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98693.1 - 2.3e-07 31.0 0.5 0.0018 18.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat GPS2_interact PF15784.5 EAX98694.1 - 0.066 13.7 1.7 0.084 13.3 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3447 PF11929.8 EAX98695.1 - 2.4e-27 94.7 5.5 2.4e-27 94.7 5.5 4.3 3 3 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98695.1 - 6.9e-11 42.6 1.9 3e-07 30.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98695.1 - 2.6e-05 24.7 1.6 0.0015 19.1 0.5 4.0 3 2 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98695.1 - 0.00024 21.3 2.2 0.002 18.4 0.1 3.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX98695.1 - 0.0073 16.6 0.0 0.76 10.2 0.0 3.7 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98695.1 - 0.0076 16.7 0.1 0.074 13.5 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat DUF563 PF04577.14 EAX98696.1 - 2.5e-30 106.2 0.0 3.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) WD40 PF00400.32 EAX98698.1 - 1.8e-19 69.7 9.6 0.0053 17.6 0.0 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX98698.1 - 4.2e-10 39.8 0.6 3.6 8.0 0.3 6.3 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAX98698.1 - 7.4e-07 28.4 2.0 1 8.2 0.0 5.0 4 2 1 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAX98698.1 - 0.0043 17.0 0.1 31 4.7 0.0 5.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 EAX98698.1 - 0.074 13.0 0.1 4.1 7.5 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Lactonase PF10282.9 EAX98698.1 - 0.09 12.0 0.0 0.33 10.2 0.0 1.9 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller DARPP-32 PF05395.12 EAX98699.1 - 0.004 17.4 19.4 0.0052 17.0 19.4 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 CBFD_NFYB_HMF PF00808.23 EAX98699.1 - 0.012 15.9 0.8 0.018 15.3 0.8 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CobT PF06213.12 EAX98699.1 - 0.019 14.4 19.8 0.023 14.1 19.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM91_C PF14648.6 EAX98699.1 - 0.032 13.1 5.7 0.038 12.8 5.7 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DDHD PF02862.17 EAX98699.1 - 0.37 10.9 6.6 0.43 10.7 6.6 1.2 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 EAX98699.1 - 0.38 9.7 7.6 0.41 9.6 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 EAX98699.1 - 0.43 8.6 10.9 0.42 8.6 10.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_11 PF13086.6 EAX98699.1 - 0.88 9.3 10.5 1.1 8.9 10.5 1.2 1 0 0 1 1 1 0 AAA domain DUF4045 PF13254.6 EAX98699.1 - 1.1 8.8 15.4 1.3 8.6 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TERB2 PF15101.6 EAX98699.1 - 1.4 8.9 9.8 2 8.5 9.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF908 PF06012.12 EAX98699.1 - 1.8 7.9 6.2 2.1 7.7 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 EAX98699.1 - 2.8 6.6 14.5 3.7 6.2 14.5 1.3 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EAX98699.1 - 2.9 5.9 21.5 3.6 5.6 21.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Neur_chan_memb PF02932.16 EAX98699.1 - 3.1 7.8 7.1 3.9 7.5 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 EAX98699.1 - 3.2 6.5 11.0 3.7 6.3 11.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 EAX98699.1 - 3.8 6.4 6.0 4.4 6.3 6.0 1.2 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 EAX98699.1 - 4.5 6.4 9.8 5.5 6.1 9.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 EAX98699.1 - 6.3 5.5 14.0 6.5 5.4 14.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EAX98699.1 - 6.4 4.8 11.1 6.3 4.8 11.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.13 EAX98699.1 - 7.6 4.8 10.0 8.8 4.5 10.0 1.0 1 0 0 1 1 1 0 Menin V_ATPase_I PF01496.19 EAX98699.1 - 9.6 4.0 10.8 10 3.9 10.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.18 EAX98700.1 - 5e-10 39.4 2.9 8.9e-10 38.6 2.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PRA-PH PF01503.17 EAX98701.1 - 0.32 11.5 3.2 10 6.6 3.5 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4108 PF13390.6 EAX98702.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF3839 PF12943.7 EAX98705.1 - 9.5e-155 513.1 11.5 1.2e-154 512.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX98705.1 - 0.049 13.3 1.8 0.15 11.7 0.2 2.6 2 2 0 2 2 2 0 Proteasome activator pa28 beta subunit Glu-tRNAGln PF02686.15 EAX98705.1 - 0.21 11.9 0.8 0.68 10.3 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAX98705.1 - 0.35 11.4 3.7 0.38 11.3 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4106 PF13388.6 EAX98708.1 - 9.2e-276 914.6 21.0 9.2e-276 914.6 21.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX98708.1 - 0.0082 16.4 3.5 0.058 13.7 0.3 3.1 3 0 0 3 3 3 1 Kidney androgen-regulated Meiosis_expr PF15163.6 EAX98709.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX98709.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX98709.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family UBX PF00789.20 EAX98710.1 - 0.0074 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain GRIP PF01465.20 EAX98711.1 - 1.4e-05 24.9 0.0 4.9e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 GRIP domain ADIP PF11559.8 EAX98711.1 - 2e-05 24.7 15.6 2e-05 24.7 15.6 17.7 3 1 15 18 18 18 8 Afadin- and alpha -actinin-Binding EzrA PF06160.12 EAX98711.1 - 0.00085 17.6 109.4 0.00085 17.6 109.4 7.2 2 1 4 6 6 6 1 Septation ring formation regulator, EzrA ZapB PF06005.12 EAX98712.1 - 0.029 14.8 0.7 0.029 14.8 0.7 11.0 6 2 4 10 10 10 0 Cell division protein ZapB Pkinase PF00069.25 EAX98713.1 - 2.6e-63 213.8 0.0 3.4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98713.1 - 1.5e-40 139.1 0.0 2.1e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98713.1 - 2.3e-08 33.7 0.0 4.5e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX98713.1 - 0.0025 16.7 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX98713.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.17 EAX98714.1 - 2.7e-46 157.7 0.0 3.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 EAX98714.1 - 0.11 12.4 1.9 0.24 11.3 1.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain F5_F8_type_C PF00754.25 EAX98715.1 - 2e-06 27.9 0.0 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain Myb_DNA-binding PF00249.31 EAX98717.1 - 1e-25 89.6 0.2 6.6e-14 51.8 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98717.1 - 7.6e-22 77.3 1.8 4.1e-12 46.1 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX98717.1 - 0.014 15.3 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like SLIDE PF09111.10 EAX98717.1 - 0.019 15.0 0.0 7.3 6.7 0.0 2.5 1 1 2 3 3 3 0 SLIDE Rap1_C PF11626.8 EAX98717.1 - 0.03 14.4 0.0 0.11 12.6 0.0 1.7 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PP2C PF00481.21 EAX98718.1 - 1.6e-40 139.4 0.4 2.3e-40 138.9 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EAX98718.1 - 1.4e-27 95.3 74.9 3.2e-06 27.4 0.5 13.3 5 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX98718.1 - 1.3e-21 76.1 50.2 0.00018 21.2 0.2 10.4 9 2 0 9 9 9 7 Leucine rich repeat LRR_6 PF13516.6 EAX98718.1 - 2e-08 33.6 31.8 2 8.6 1.3 12.4 13 0 0 13 13 13 4 Leucine Rich repeat PP2C_2 PF13672.6 EAX98718.1 - 1.1e-06 28.5 0.1 1.8e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 EAX98718.1 - 3.2e-05 23.5 30.3 0.019 14.5 1.0 6.0 3 2 1 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 EAX98718.1 - 0.0015 18.8 38.4 4.8 8.1 0.1 13.0 12 3 0 12 12 12 1 Leucine Rich Repeat C2 PF00168.30 EAX98719.1 - 0.0082 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 C2 domain Copine PF07002.16 EAX98720.1 - 4.3e-73 245.4 0.0 5.9e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EAX98720.1 - 2e-16 60.1 0.1 1.4e-12 47.7 0.0 2.6 2 1 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EAX98720.1 - 0.00054 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus FrhB_FdhB_C PF04432.13 EAX98720.1 - 0.021 14.6 0.1 0.064 13.1 0.0 1.7 1 1 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Citrate_bind PF16114.5 EAX98720.1 - 0.09 12.3 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding DUF4497 PF14924.6 EAX98720.1 - 0.13 12.8 0.1 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) B56 PF01603.20 EAX98721.1 - 7.9e-66 222.7 3.0 9.5e-66 222.5 3.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec34 PF04136.15 EAX98721.1 - 0.077 12.9 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 Sec34-like family 14-3-3 PF00244.20 EAX98721.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 14-3-3 protein DUF1290 PF06947.12 EAX98722.1 - 0.045 13.8 0.2 0.18 11.9 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Myb_DNA-binding PF00249.31 EAX98723.1 - 1.4e-27 95.6 3.1 1.3e-13 50.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98723.1 - 1.3e-19 70.2 1.9 1.4e-09 38.0 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98723.1 - 0.00052 20.0 0.1 0.2 11.7 0.1 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAX98723.1 - 0.0039 17.3 0.5 1.3 9.3 0.4 2.8 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAX98723.1 - 0.012 15.5 1.7 0.025 14.5 0.1 2.2 2 2 1 3 3 3 0 Myb DNA-binding like DUF722 PF05263.11 EAX98723.1 - 0.045 14.0 1.2 1.4 9.1 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF722) ABC_tran PF00005.27 EAX98724.1 - 6.1e-25 88.3 0.0 1e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX98724.1 - 2.8e-12 47.1 0.3 1.2e-05 25.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAX98724.1 - 2.2e-06 27.3 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAX98724.1 - 5.5e-05 23.8 0.2 9e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAX98724.1 - 0.00018 21.2 0.2 0.00039 20.1 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EAX98724.1 - 0.00072 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX98724.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.25 EAX98724.1 - 0.002 17.8 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 EAX98724.1 - 0.003 16.7 0.3 0.0054 15.8 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EAX98724.1 - 0.0041 16.9 0.0 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EAX98724.1 - 0.0058 16.5 0.1 0.023 14.6 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 EAX98724.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EAX98724.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EAX98724.1 - 0.025 14.3 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EAX98724.1 - 0.029 14.3 0.2 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 NTPase AAA_18 PF13238.6 EAX98724.1 - 0.03 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX98724.1 - 0.036 14.3 0.1 0.17 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAX98724.1 - 0.051 13.1 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EAX98724.1 - 0.076 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 EAX98724.1 - 0.08 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 EAX98724.1 - 0.08 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAX98724.1 - 0.088 13.0 0.4 0.17 12.1 0.4 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAX98724.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 EAX98724.1 - 0.11 12.1 0.6 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EAX98724.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 EAX98724.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EAX98724.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX98724.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAX98724.1 - 0.18 12.3 0.1 0.47 10.9 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAX98724.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC2_membrane_3 PF12698.7 EAX98724.1 - 0.45 9.6 20.8 0.91 8.6 20.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein UPF0047 PF01894.17 EAX98725.1 - 4.8e-37 126.6 0.0 5.6e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Lipase_3 PF01764.25 EAX98727.1 - 1e-11 44.9 0.0 1.9e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.13 EAX98727.1 - 0.039 12.5 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TatD_DNase PF01026.21 EAX98728.1 - 1.7e-60 204.5 0.0 1.9e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EAX98728.1 - 0.055 13.3 0.0 8.6 6.0 0.0 2.6 1 1 1 2 2 2 0 Amidohydrolase Metallophos PF00149.28 EAX98729.1 - 1.2e-30 107.6 0.1 2e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX98729.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_19 PF14559.6 EAX98730.1 - 0.0048 17.4 0.0 0.046 14.2 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAX98730.1 - 0.16 12.9 0.1 11 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PSP PF04046.16 EAX98731.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98732.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX98733.1 - 0.032 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX98734.1 - 2.2e-65 216.6 46.3 1.5e-34 117.9 16.2 5.8 4 2 2 7 7 7 3 Phage tail repeat like DUF4116 PF13475.6 EAX98734.1 - 0.097 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX98734.1 - 0.12 12.9 4.1 3.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3839 PF12943.7 EAX98736.1 - 7.7e-130 431.6 13.3 2.4e-129 430.0 13.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) KilA-N PF04383.13 EAX98736.1 - 0.0071 16.2 0.4 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 KilA-N domain Fez1 PF06818.15 EAX98736.1 - 0.012 16.1 1.1 0.026 15.0 0.1 1.9 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX98736.1 - 0.11 12.9 0.5 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX98736.1 - 0.39 11.2 4.3 2.6 8.6 0.5 2.8 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX98737.1 - 0.0034 17.1 0.1 0.0086 15.7 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98738.1 - 1.3e-39 136.0 2.9 1.6e-39 135.7 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98738.1 - 0.084 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta CDC45 PF02724.14 EAX98740.1 - 4.9e-05 21.9 11.4 5.6e-05 21.7 11.4 1.0 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 EAX98740.1 - 0.00018 20.3 16.5 0.00019 20.2 16.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.16 EAX98740.1 - 0.00024 21.2 2.8 0.00034 20.8 2.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 EAX98740.1 - 0.0011 18.0 4.6 0.0011 18.0 4.6 2.0 1 1 1 2 2 2 1 Serine incorporator (Serinc) tRNA_anti-like PF12869.7 EAX98740.1 - 0.0088 15.7 0.4 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 tRNA_anti-like CBP_BcsG PF11658.8 EAX98740.1 - 0.011 14.2 0.2 0.013 13.9 0.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Tmemb_9 PF05434.11 EAX98740.1 - 0.015 15.2 7.0 0.015 15.2 7.0 2.1 1 1 1 2 2 2 0 TMEM9 ABC2_membrane_3 PF12698.7 EAX98740.1 - 0.017 14.2 1.8 0.023 13.8 1.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein O-antigen_lig PF13425.6 EAX98740.1 - 0.02 13.7 7.1 0.029 13.2 7.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1616 PF07760.11 EAX98740.1 - 0.031 13.7 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Silic_transp PF03842.13 EAX98740.1 - 0.045 12.1 0.8 0.061 11.6 0.8 1.2 1 0 0 1 1 1 0 Silicon transporter PA26 PF04636.13 EAX98740.1 - 0.05 12.5 5.8 0.062 12.2 5.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4834 PF16118.5 EAX98740.1 - 0.06 14.3 17.4 3 8.9 17.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM192 PF14802.6 EAX98740.1 - 0.071 12.2 0.3 0.12 11.5 0.3 1.4 1 0 0 1 1 1 0 TMEM192 family Shisa PF13908.6 EAX98740.1 - 0.097 12.9 4.5 0.041 14.1 1.8 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SpoIIIAH PF12685.7 EAX98740.1 - 0.13 12.1 20.9 1.1 9.0 20.9 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein SID-1_RNA_chan PF13965.6 EAX98740.1 - 0.15 10.4 11.5 0.23 9.9 11.5 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 EAX98740.1 - 0.17 10.0 12.5 0.2 9.7 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_C37 PF05416.12 EAX98740.1 - 0.23 9.9 5.9 0.26 9.8 5.9 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4446 PF14584.6 EAX98740.1 - 0.32 11.0 6.6 0.25 11.3 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) SLC12 PF03522.15 EAX98740.1 - 0.37 9.8 10.8 0.46 9.4 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2681 PF10883.8 EAX98740.1 - 0.49 10.8 8.3 0.22 11.9 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.19 EAX98740.1 - 0.5 8.2 10.1 0.84 7.5 10.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family EphA2_TM PF14575.6 EAX98740.1 - 0.53 11.2 7.8 3.4 8.6 7.8 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.17 EAX98740.1 - 1 10.4 9.4 1.8e+02 3.2 9.4 2.7 1 1 0 1 1 1 0 Conotoxin Cadherin_C_2 PF16492.5 EAX98740.1 - 1.1 10.0 5.3 8.2 7.2 5.3 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Mem_trans PF03547.18 EAX98740.1 - 1.1 7.6 6.1 1.5 7.2 6.1 1.2 1 0 0 1 1 1 0 Membrane transport protein CLN3 PF02487.17 EAX98740.1 - 1.3 8.0 8.0 0.16 11.0 3.5 1.5 1 1 1 2 2 2 0 CLN3 protein Ly49 PF08391.10 EAX98740.1 - 1.5 9.2 14.8 11 6.4 14.8 2.1 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Connexin PF00029.19 EAX98740.1 - 1.6 8.4 14.7 23 4.6 14.7 2.0 1 1 0 1 1 1 0 Connexin Vpu PF00558.19 EAX98740.1 - 2.8 7.8 9.5 0.09 12.6 3.1 1.9 2 0 0 2 2 1 0 Vpu protein DUF2371 PF10177.9 EAX98740.1 - 4.7 7.4 6.0 10 6.3 5.8 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) G0-G1_switch_2 PF15103.6 EAX98740.1 - 8.5 6.9 9.3 0.53 10.7 0.8 2.1 1 1 1 2 2 2 0 G0/G1 switch protein 2 CSG2 PF16965.5 EAX98740.1 - 8.7 5.2 9.7 0.84 8.5 4.7 1.6 1 1 1 2 2 2 0 Ceramide synthase regulator MFS_1 PF07690.16 EAX98741.1 - 0.053 12.4 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily BatD PF13584.6 EAX98741.1 - 0.098 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2371 PF10177.9 EAX98741.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) hEGF PF12661.7 EAX98743.1 - 0.28 11.9 0.4 0.28 11.9 0.4 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF TIL PF01826.17 EAX98743.1 - 9.3 6.6 16.9 4.8 7.5 8.8 2.5 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Laminin_B PF00052.18 EAX98744.1 - 0.016 15.1 0.1 0.016 15.1 0.1 2.4 2 0 0 2 2 2 0 Laminin B (Domain IV) DUF3447 PF11929.8 EAX98745.1 - 4.3e-41 138.7 6.4 4.3e-41 138.7 6.4 3.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98745.1 - 2.6e-30 104.4 2.8 1.9e-10 41.0 0.0 7.1 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98745.1 - 7.6e-29 100.1 7.4 8.3e-14 51.9 0.5 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98745.1 - 6e-22 77.1 1.6 0.00013 22.2 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX98745.1 - 7.9e-22 77.0 0.2 1.6e-08 34.6 0.1 4.7 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98745.1 - 2.8e-17 61.0 5.7 0.0023 18.3 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat FeS PF04060.13 EAX98745.1 - 0.23 11.1 0.9 25 4.6 0.1 3.3 3 0 0 3 3 3 0 Putative Fe-S cluster PRK PF00485.18 EAX98746.1 - 1.4e-15 57.6 0.1 6.5e-15 55.4 0.1 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 EAX98746.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 EAX98746.1 - 0.097 12.6 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RecA PF00154.21 EAX98746.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Glyco_hydro_1 PF00232.18 EAX98747.1 - 2.2e-81 273.6 4.2 3.1e-81 273.1 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_42 PF02449.15 EAX98747.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase Ribosomal_S28e PF01200.18 EAX98748.1 - 6.2e-31 106.2 2.9 7.1e-31 106.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PSP PF04046.16 EAX98749.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98750.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat VHS PF00790.19 EAX98753.1 - 0.045 13.6 1.7 0.12 12.2 0.4 2.5 2 1 1 3 3 3 0 VHS domain RPAP3_C PF13877.6 EAX98753.1 - 0.15 12.6 1.2 0.38 11.3 0.1 2.4 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Adaptin_N PF01602.20 EAX98754.1 - 2.5e-34 118.7 19.5 2.5e-34 118.7 19.5 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EAX98754.1 - 0.0038 17.5 0.1 0.013 15.8 0.1 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain RNA_pol_Rpb4 PF03874.16 EAX98754.1 - 6.7 7.1 8.9 6.9 7.0 0.0 4.5 4 2 0 4 4 4 0 RNA polymerase Rpb4 DsrC PF04358.13 EAX98755.1 - 0.12 12.9 0.4 0.48 11.0 0.4 2.1 1 0 0 1 1 1 0 DsrC like protein DUF4108 PF13390.6 EAX98758.1 - 1.3e-57 193.7 5.8 1.5e-57 193.6 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX98758.1 - 0.12 11.4 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_A32 PF04665.12 EAX98760.1 - 1.3e-06 28.1 2.1 1.3e-06 28.1 2.1 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX98760.1 - 2.9e-05 24.4 0.2 0.0002 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX98760.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX98760.1 - 0.00018 21.6 3.3 0.00034 20.7 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX98760.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX98760.1 - 0.0014 18.5 0.6 0.0035 17.2 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX98760.1 - 0.0021 17.7 0.5 0.015 15.0 0.2 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX98760.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 EAX98760.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX98760.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX98760.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX98760.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX98760.1 - 0.31 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX98761.1 - 1.3e-31 108.7 0.5 2.8e-31 107.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX98761.1 - 0.11 12.5 0.3 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAX98762.1 - 2.9e-157 521.4 11.5 3.5e-157 521.1 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX98762.1 - 0.087 13.1 1.4 9.2 6.7 0.1 3.5 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAX98762.1 - 0.095 13.2 4.6 2.1 8.9 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AIG1 PF04548.16 EAX98763.1 - 0.00015 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family LRR_5 PF13306.6 EAX98764.1 - 6.2e-81 268.7 48.7 8.4e-22 77.5 1.7 5.4 3 1 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98764.1 - 1.6e-20 72.6 3.3 0.0015 18.3 0.4 8.6 7 3 3 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 EAX98764.1 - 0.0041 17.5 9.5 15 6.1 0.0 7.3 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) PCI PF01399.27 EAX98765.1 - 3e-09 37.3 0.3 3e-09 37.3 0.3 2.4 3 1 0 3 3 3 1 PCI domain B2 PF11473.8 EAX98765.1 - 0.073 12.9 0.4 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 RNA binding protein B2 TPR_2 PF07719.17 EAX98765.1 - 2.8 8.3 5.9 2.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 EAX98766.1 - 1.1e-34 120.2 3.9 3.2e-34 118.8 3.9 1.8 1 0 0 1 1 1 1 RhoGEF domain Kelch_4 PF13418.6 EAX98766.1 - 9.7e-24 83.1 0.2 2.5e-08 33.8 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAX98766.1 - 4.9e-19 67.9 0.8 0.0002 21.5 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 EAX98766.1 - 1.8e-18 66.4 0.0 0.00052 20.2 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAX98766.1 - 1.2e-17 63.4 0.1 5e-06 26.4 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EAX98766.1 - 9.3e-17 60.3 0.5 0.00074 19.1 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EAX98766.1 - 4.6e-16 58.1 3.0 0.0013 18.7 0.0 5.2 6 0 0 6 6 6 3 Kelch motif MRC1 PF09444.10 EAX98766.1 - 0.16 12.5 0.9 0.32 11.5 0.9 1.5 1 0 0 1 1 1 0 MRC1-like domain DUF4107 PF13389.6 EAX98768.1 - 3.9e-72 241.7 3.2 5.1e-72 241.3 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98768.1 - 0.057 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX98769.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Pox_A32 PF04665.12 EAX98770.1 - 4.6e-07 29.6 0.1 9.1e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein KilA-N PF04383.13 EAX98772.1 - 9.5e-07 28.7 0.1 1.5e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAX98774.1 - 1.7e-153 509.0 11.6 2e-153 508.7 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PA28_beta PF02252.18 EAX98774.1 - 0.023 14.4 1.5 0.085 12.5 0.3 2.5 1 1 0 2 2 2 0 Proteasome activator pa28 beta subunit KELK PF15796.5 EAX98774.1 - 0.055 13.9 5.0 0.44 11.0 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAX98774.1 - 0.093 13.2 1.4 0.21 12.0 0.2 1.9 2 0 0 2 2 2 0 Fez1 DUF2408 PF10303.9 EAX98774.1 - 0.51 10.9 4.5 0.57 10.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DNA_pol_B_2 PF03175.13 EAX98775.1 - 5.6e-10 38.7 2.9 3.5e-09 36.0 2.8 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX98775.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 PapD_N PF00345.20 EAX98776.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX98777.1 - 0.016 15.6 0.5 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAX98778.1 - 0.096 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX98779.1 - 0.075 13.0 11.1 0.12 12.4 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX98780.1 - 0.015 15.7 1.1 0.02 15.3 1.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain WD40 PF00400.32 EAX98781.1 - 6e-09 36.4 7.3 0.031 15.1 0.2 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat Lactonase PF10282.9 EAX98781.1 - 0.0037 16.6 0.2 0.0059 15.9 0.2 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller tify PF06200.14 EAX98781.1 - 0.065 12.6 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 tify domain PPV_E2_C PF00511.17 EAX98781.1 - 0.18 12.0 1.7 3.4 7.9 0.2 2.5 2 0 0 2 2 2 0 E2 (early) protein, C terminal RRM_1 PF00076.22 EAX98782.1 - 0.0024 17.6 0.7 0.0043 16.8 0.7 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX98782.1 - 0.0038 17.2 0.2 0.0083 16.1 0.2 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ank_2 PF12796.7 EAX98783.1 - 2.6e-21 76.0 9.0 1.6e-06 28.6 0.1 4.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98783.1 - 1.2e-18 65.3 4.3 0.0013 19.1 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EAX98783.1 - 7.8e-13 48.7 0.8 0.00034 21.1 0.0 5.9 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98783.1 - 7.6e-12 45.2 0.3 0.053 13.9 0.0 6.5 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98783.1 - 9.7e-08 32.1 0.9 1 9.9 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 EAX98783.1 - 3.3 7.7 6.5 3 7.8 0.3 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) Adaptin_N PF01602.20 EAX98784.1 - 1.1e-87 294.8 0.1 1.4e-87 294.5 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EAX98784.1 - 9e-14 51.6 0.2 8e-07 29.4 0.0 5.9 4 2 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EAX98784.1 - 2e-12 47.5 0.4 4.9e-09 36.4 0.0 4.7 3 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX98784.1 - 1.9e-07 30.7 0.9 1.5 9.3 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EAX98784.1 - 0.22 12.1 1.7 4.7 7.8 0.1 3.7 3 1 0 3 3 3 0 HEAT-like repeat SLC35F PF06027.12 EAX98785.1 - 8.1e-09 35.4 7.9 8.1e-09 35.4 7.9 1.8 2 1 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 EAX98785.1 - 1.7e-08 34.7 2.9 1.7e-08 34.7 2.9 4.0 3 1 0 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 EAX98785.1 - 1.7e-05 24.0 9.0 3.7e-05 22.8 8.2 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 EAX98785.1 - 8.2e-05 21.9 0.9 0.00015 21.1 0.9 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF883 PF05957.13 EAX98786.1 - 0.0021 18.6 12.2 0.0021 18.6 12.2 6.0 1 1 6 7 7 7 2 Bacterial protein of unknown function (DUF883) Phage_GP20 PF06810.11 EAX98786.1 - 0.0024 17.7 16.7 0.0024 17.7 16.7 5.3 1 1 3 4 4 4 1 Phage minor structural protein GP20 APG6_N PF17675.1 EAX98786.1 - 0.011 16.3 18.9 0.011 16.3 18.9 4.6 1 1 4 5 5 5 0 Apg6 coiled-coil region DUF5082 PF16888.5 EAX98786.1 - 0.029 14.6 2.7 0.029 14.6 2.7 6.1 2 2 4 6 6 6 0 Domain of unknown function (DUF5082) CENP-H PF05837.12 EAX98786.1 - 0.049 14.0 2.1 0.049 14.0 2.1 5.6 1 1 5 6 6 6 0 Centromere protein H (CENP-H) Fez1 PF06818.15 EAX98786.1 - 0.76 10.2 79.7 15 6.0 33.2 3.9 1 1 3 4 4 4 0 Fez1 DUF4515 PF14988.6 EAX98786.1 - 1.4 8.7 80.1 3.2 7.6 22.0 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4515) DUF2563 PF10817.8 EAX98786.1 - 2.3 8.9 4.0 11 6.7 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2563) ATP-synt_C PF00137.21 EAX98787.1 - 5.8e-22 77.8 40.6 1.2e-12 47.9 16.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PsaL PF02605.15 EAX98787.1 - 0.015 15.0 2.1 0.05 13.3 0.3 2.2 1 1 0 2 2 2 0 Photosystem I reaction centre subunit XI RhoGAP PF00620.27 EAX98788.1 - 2.5e-21 76.1 0.0 8.6e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 EAX98788.1 - 4.8e-15 56.0 0.1 1.7e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 EAX98788.1 - 0.037 14.1 8.3 0.095 12.8 8.3 1.7 1 0 0 1 1 1 0 WW domain Ashwin PF15323.6 EAX98789.1 - 0.5 10.3 14.7 0.81 9.7 14.7 1.3 1 0 0 1 1 1 0 Developmental protein Trypan_PARP PF05887.11 EAX98790.1 - 0.022 14.7 10.4 0.03 14.3 10.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAX98791.1 - 0.0055 16.7 0.3 0.0073 16.3 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX98792.1 - 0.02 15.3 0.7 0.025 15.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX98792.1 - 2.4 7.1 4.8 2.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX98792.1 - 4.7 7.9 6.8 10 6.8 6.8 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAX98793.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX98793.1 - 0.06 13.4 0.2 0.075 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3839 PF12943.7 EAX98795.1 - 1.1e-148 493.2 10.3 1.4e-148 492.9 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX98795.1 - 0.42 11.1 2.6 9.8 6.7 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Amidase02_C PF12123.8 EAX98796.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98797.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98797.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Ank_4 PF13637.6 EAX98798.1 - 3.7e-16 59.2 0.3 3.9e-09 36.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98798.1 - 2.4e-12 46.8 0.1 3.3e-11 43.2 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98798.1 - 1.8e-11 44.0 0.0 1.3e-05 25.5 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX98798.1 - 1e-09 38.8 0.6 3.5e-09 37.1 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98798.1 - 1e-07 31.6 0.0 0.0049 17.3 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat CCDC92 PF14916.6 EAX98798.1 - 0.008 15.9 4.4 0.014 15.1 3.0 2.2 2 0 0 2 2 2 1 Coiled-coil domain of unknown function PH_8 PF15409.6 EAX98798.1 - 0.039 14.2 0.0 0.52 10.6 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.25 EAX98799.1 - 1.9e-64 217.6 0.0 3.6e-64 216.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98799.1 - 6.1e-37 127.3 0.0 1e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98799.1 - 2.2e-09 37.1 0.0 2.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAX98799.1 - 1.9e-05 23.7 0.6 0.0002 20.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EAX98799.1 - 0.0012 18.5 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX98799.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAX98799.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EAX98799.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EAX98800.1 - 2.2e-24 85.4 1.5 2.2e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98800.1 - 2.1e-20 72.7 2.7 3.3e-12 46.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98800.1 - 2.4e-05 24.3 0.2 0.088 12.8 0.0 2.3 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX98800.1 - 0.0024 17.7 0.2 0.64 10.0 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAX98800.1 - 1.8 8.9 4.1 9.1 6.7 0.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 EAX98800.1 - 1.8 9.0 7.8 0.56 10.6 2.0 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cecropin PF00272.19 EAX98800.1 - 2.2 8.1 0.0 2.2 8.1 0.0 2.4 3 0 0 3 3 3 0 Cecropin family DSPn PF14671.6 EAX98801.1 - 5.2e-17 62.6 0.0 1.3e-15 58.1 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EAX98801.1 - 2e-10 40.6 0.0 6.9e-10 38.9 0.0 1.9 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAX98801.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ndc80_HEC PF03801.13 EAX98802.1 - 4.9e-05 23.0 0.4 4.9e-05 23.0 0.4 2.7 2 1 0 2 2 2 1 HEC/Ndc80p family Bap31_Bap29_C PF18035.1 EAX98802.1 - 0.003 17.5 0.1 0.003 17.5 0.1 5.9 6 1 0 6 6 6 1 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 EAX98802.1 - 0.015 15.5 7.5 0.015 15.5 7.5 5.3 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PseudoU_synth_2 PF00849.22 EAX98803.1 - 5e-19 68.9 0.0 7.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase NTPase_1 PF03266.15 EAX98804.1 - 2.3e-13 50.4 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 EAX98804.1 - 6.7e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EAX98804.1 - 7.1e-05 23.2 0.0 0.00019 21.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAX98804.1 - 0.006 16.6 0.0 0.18 11.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAX98804.1 - 0.015 15.2 0.0 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EAX98804.1 - 0.024 15.2 0.0 0.04 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EAX98804.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EAX98804.1 - 0.051 13.6 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EAX98804.1 - 0.27 10.9 0.0 1.1 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NosD PF05048.13 EAX98805.1 - 1.4 8.1 19.4 1.5 8.1 18.4 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Bromodomain PF00439.25 EAX98806.1 - 1.9e-17 63.1 0.3 4.2e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EAX98806.1 - 0.00091 19.4 2.1 0.0011 19.0 0.6 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation RhoGAP PF00620.27 EAX98806.1 - 0.0048 16.7 4.1 0.1 12.4 0.2 2.5 2 1 1 3 3 3 2 RhoGAP domain Transcrip_reg PF01709.20 EAX98806.1 - 0.011 15.2 0.3 0.075 12.4 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HsbA PF12296.8 EAX98806.1 - 0.03 14.8 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A RPW8 PF05659.11 EAX98806.1 - 0.14 11.8 1.5 0.91 9.2 0.3 2.6 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3447 PF11929.8 EAX98807.1 - 6.4e-08 32.5 1.5 6.4e-08 32.5 1.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX98807.1 - 7.7e-05 23.2 0.1 0.084 13.5 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98807.1 - 0.0016 19.0 0.0 3.2 8.4 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98807.1 - 0.0017 18.7 0.1 4 8.3 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat ATG2_CAD PF13329.6 EAX98808.1 - 0.026 14.3 0.0 0.12 12.1 0.0 2.2 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif HTH_ParB PF17762.1 EAX98808.1 - 0.14 11.9 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 HTH domain found in ParB protein Ank_3 PF13606.6 EAX98809.1 - 1.5e-10 40.4 0.1 0.16 12.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX98809.1 - 9.1e-10 38.9 0.0 0.00092 19.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98809.1 - 3.6e-09 37.1 0.0 1.4e-05 25.6 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98809.1 - 1.7e-05 25.1 0.0 2.8 8.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeat LRR_5 PF13306.6 EAX98810.1 - 3.1e-22 78.9 17.4 1.2e-13 51.2 1.6 2.8 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98810.1 - 0.017 14.9 0.0 8.6 6.2 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat Lipid_bd PF12888.7 EAX98811.1 - 0.36 11.3 6.8 5.3 7.5 0.1 4.2 3 1 1 4 4 4 0 Lipid-binding putative hydrolase BACK PF07707.15 EAX98813.1 - 3.1e-08 33.6 0.0 7.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch RepB-RCR_reg PF10723.9 EAX98813.1 - 0.06 13.3 0.5 0.13 12.2 0.3 1.6 1 1 0 1 1 1 0 Replication regulatory protein RepB DUF563 PF04577.14 EAX98815.1 - 1.5e-28 100.4 0.9 3.5e-28 99.2 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) PSP PF04046.16 EAX98816.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98817.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX98818.1 - 0.071 13.6 0.7 0.15 12.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DHOR PF06537.11 EAX98819.1 - 0.0074 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Di-haem oxidoreductase, putative peroxidase DUF3839 PF12943.7 EAX98820.1 - 1.5e-142 473.1 10.6 1.9e-142 472.8 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) zf-C4pol PF14260.6 EAX98820.1 - 0.33 11.4 3.3 2.9 8.4 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta KELK PF15796.5 EAX98820.1 - 0.47 10.9 5.6 3.2 8.3 0.2 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAX98821.1 - 3.1e-58 197.2 0.0 4.2e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98821.1 - 1.7e-30 106.2 0.0 2e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98821.1 - 3.7e-09 36.3 0.0 9.9e-08 31.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX98821.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAX98821.1 - 0.0098 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_endo_I PF05367.11 EAX98821.1 - 0.022 14.4 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Phage endonuclease I APH PF01636.23 EAX98821.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1493 PF07377.12 EAX98822.1 - 0.078 13.4 0.4 0.17 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX98823.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Lactamase_B_2 PF12706.7 EAX98826.1 - 2.2e-14 53.5 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAX98826.1 - 5.7e-13 49.1 0.0 7.1e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAX98826.1 - 5.7e-05 23.2 0.1 0.00018 21.6 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Imm32 PF15566.6 EAX98827.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 32 zf-UBR PF02207.20 EAX98828.1 - 8.7e-05 22.6 18.3 0.00017 21.7 18.3 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) NAAA-beta PF15508.6 EAX98828.1 - 0.19 12.1 0.3 4.5 7.6 0.0 2.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase tRNA_anti-like PF12869.7 EAX98832.1 - 0.027 14.1 1.1 0.053 13.1 0.3 1.8 1 1 1 2 2 2 0 tRNA_anti-like ODV-E18 PF10717.9 EAX98832.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 WD40 PF00400.32 EAX98834.1 - 0.0013 19.5 2.6 0.02 15.8 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat WHIM1 PF15612.6 EAX98837.1 - 0.078 12.5 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Med4 PF10018.9 EAX98837.1 - 0.12 12.0 6.2 0.21 11.2 5.6 1.7 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3450 PF11932.8 EAX98837.1 - 2.3 7.5 12.5 6.2 6.0 11.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EAX98837.1 - 6.6 6.9 11.8 17 5.6 11.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PhoLip_ATPase_C PF16212.5 EAX98838.1 - 2.7e-08 33.9 28.1 5.7e-08 32.8 28.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Repressor_Mnt PF11423.8 EAX98838.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt Myb_DNA-binding PF00249.31 EAX98839.1 - 1.3e-23 82.9 0.3 1.5e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98839.1 - 7.3e-20 71.0 0.8 5.3e-12 45.8 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98839.1 - 1.6e-06 28.2 0.4 0.0036 17.3 0.0 3.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX98839.1 - 0.00055 19.8 0.2 0.062 13.2 0.2 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Ank_2 PF12796.7 EAX98840.1 - 6.3e-43 145.3 12.1 3e-13 50.2 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98840.1 - 7.7e-35 118.8 3.9 6.3e-10 39.4 0.1 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98840.1 - 6.5e-28 96.4 7.4 7.5e-05 22.9 0.1 6.7 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98840.1 - 9e-24 81.0 6.9 0.0014 18.9 0.1 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EAX98840.1 - 2.4e-18 65.7 11.9 0.00014 22.2 0.2 7.3 6 1 1 7 7 7 5 Ankyrin repeat RimK PF08443.11 EAX98840.1 - 0.019 14.5 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Ras PF00071.22 EAX98842.1 - 1.2e-26 93.3 0.0 1.4e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX98842.1 - 1.4e-20 73.7 0.0 1.9e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX98842.1 - 6.4e-12 45.3 0.0 7.9e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX98842.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX98842.1 - 0.0012 18.4 0.0 0.0042 16.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAX98842.1 - 0.0017 17.9 0.0 0.0066 16.0 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EAX98842.1 - 0.0053 16.2 0.0 0.0086 15.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX98842.1 - 0.017 15.0 0.0 1.8 8.4 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 EAX98842.1 - 0.02 13.9 0.0 0.86 8.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MnmE_helical PF12631.7 EAX98842.1 - 0.062 13.5 0.0 0.062 13.5 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain SIR2 PF02146.17 EAX98843.1 - 8.9e-43 146.3 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Flavokinase PF01687.17 EAX98844.1 - 1.1e-32 112.6 0.0 1.2e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase HTH_36 PF13730.6 EAX98844.1 - 0.19 11.7 0.0 0.41 10.7 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain DUF1923 PF09083.10 EAX98845.1 - 0.28 10.9 2.7 79 3.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1923) BBS2_Mid PF14783.6 EAX98846.1 - 0.097 12.7 3.5 0.43 10.6 0.0 3.7 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PWI PF01480.17 EAX98846.1 - 0.82 10.0 5.9 3.5 8.0 0.1 4.9 4 0 0 4 4 4 0 PWI domain AAA_14 PF13173.6 EAX98848.1 - 5.8e-05 23.1 0.3 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DCX PF03607.17 EAX98848.1 - 0.00041 20.4 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 Doublecortin KHA PF11834.8 EAX98848.1 - 0.0018 18.3 1.1 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel Pox_A32 PF04665.12 EAX98848.1 - 0.0078 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_28 PF13521.6 EAX98848.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX98848.1 - 0.037 14.4 0.0 0.16 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain CIDE-N PF02017.15 EAX98848.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 CIDE-N domain AAA_33 PF13671.6 EAX98848.1 - 0.12 12.5 0.4 0.53 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain Amidase02_C PF12123.8 EAX98850.1 - 0.011 15.4 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX98851.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX98851.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3781 PF12636.7 EAX98852.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Gly-zipper_Omp PF13488.6 EAX98853.1 - 0.008 16.2 9.1 0.008 16.2 9.1 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAX98853.1 - 0.25 11.7 4.9 0.39 11.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX98853.1 - 0.86 9.7 5.5 1.4 9.0 5.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif UCH PF00443.29 EAX98854.1 - 4.9e-54 183.5 0.0 1.5e-53 181.9 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX98854.1 - 1.3e-12 48.2 1.8 2.1e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 EAX98854.1 - 4.4e-09 36.4 15.8 0.00041 20.1 4.4 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAX98854.1 - 0.014 14.9 3.5 0.12 11.8 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3447 PF11929.8 EAX98855.1 - 1.4e-38 130.7 2.7 1.4e-38 130.7 2.7 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98855.1 - 3e-33 113.8 6.0 2.5e-06 27.9 0.0 8.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98855.1 - 1.2e-30 105.9 7.3 2e-13 50.7 0.3 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98855.1 - 2.1e-29 100.7 2.6 1.4e-06 28.5 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAX98855.1 - 2.3e-26 91.5 0.6 5.9e-08 32.8 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98855.1 - 3e-25 85.5 3.4 0.00023 21.4 0.0 7.9 9 0 0 9 9 9 5 Ankyrin repeat MetallophosN PF16371.5 EAX98855.1 - 0.024 14.9 2.1 1.4 9.2 0.1 3.2 3 2 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Sigma70_r4_2 PF08281.12 EAX98856.1 - 0.00051 19.7 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Myb_DNA-binding PF00249.31 EAX98856.1 - 0.002 18.3 0.1 0.57 10.4 0.0 2.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain HTH_29 PF13551.6 EAX98856.1 - 0.012 15.6 0.1 0.049 13.7 0.0 1.9 2 1 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.12 EAX98856.1 - 0.059 13.3 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_24 PF13412.6 EAX98856.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EAX98856.1 - 0.14 12.0 0.1 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain GerE PF00196.19 EAX98856.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF4107 PF13389.6 EAX98857.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX98858.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX98859.1 - 1.1e-153 509.6 12.2 1.5e-153 509.2 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX98859.1 - 2.8 8.5 6.1 1.3 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX98859.1 - 4.8 7.7 7.5 1.9 9.0 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2939 PF11159.8 EAX98860.1 - 0.018 15.5 0.7 0.022 15.2 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX98860.1 - 2.5 7.0 4.8 2.5 7.0 4.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAX98860.1 - 5.1 7.8 6.9 11 6.7 6.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain FAS_N PF17828.1 EAX98861.1 - 0.015 15.3 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX98863.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain GPS2_interact PF15784.5 EAX98865.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98865.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Rot1 PF10681.9 EAX98868.1 - 0.14 11.7 0.2 0.14 11.7 0.2 2.6 2 1 1 3 3 3 0 Chaperone for protein-folding within the ER, fungal UQ_con PF00179.26 EAX98870.1 - 3.5e-32 111.0 0.1 4e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAX98870.1 - 0.004 17.4 0.1 0.005 17.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain DUF2251 PF10008.9 EAX98870.1 - 0.099 12.8 0.1 0.32 11.1 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) Sulfatase PF00884.23 EAX98871.1 - 1.5e-10 41.0 2.8 5.9e-10 39.0 2.8 2.0 1 1 0 1 1 1 1 Sulfatase Glyoxalase PF00903.25 EAX98871.1 - 0.047 13.9 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ubiquitin PF00240.23 EAX98872.1 - 6.1e-12 45.1 0.4 1.7e-05 24.4 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin family Ada3 PF10198.9 EAX98872.1 - 0.05 13.7 1.5 0.34 11.1 0.1 2.5 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Thioredoxin_4 PF13462.6 EAX98873.1 - 2.1e-11 44.3 0.0 3.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EAX98873.1 - 0.0033 17.2 0.3 1.4 8.7 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TLD PF07534.16 EAX98874.1 - 3.1e-25 89.0 0.5 7.3e-25 87.8 0.5 1.7 1 0 0 1 1 1 1 TLD zf-B_box PF00643.24 EAX98874.1 - 1.6e-12 47.4 25.6 4.5e-07 29.9 6.6 2.5 2 0 0 2 2 2 2 B-box zinc finger MerR_1 PF13411.6 EAX98874.1 - 0.057 13.5 0.4 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 MerR HTH family regulatory protein BLOC1_2 PF10046.9 EAX98874.1 - 0.69 10.3 5.4 26 5.2 0.0 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PSP PF04046.16 EAX98876.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98877.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Ham1p_like PF01725.16 EAX98879.1 - 5.2e-52 176.5 0.0 5.8e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family EspB_PE PF18625.1 EAX98880.1 - 0.17 12.4 1.0 2.3 8.8 0.0 3.1 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain DNA_pol_B_2 PF03175.13 EAX98882.1 - 2.4e-23 82.8 4.1 3.4e-23 82.3 4.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF2939 PF11159.8 EAX98884.1 - 0.0042 17.5 0.7 0.005 17.2 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX98884.1 - 3.4 7.6 6.9 3.7 7.5 6.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX98885.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX98886.1 - 0.81 9.7 8.6 0.95 9.4 8.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAX98887.1 - 0.037 13.0 0.1 0.037 13.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAX98888.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3800 PF12686.7 EAX98889.1 - 0.068 13.8 0.1 0.077 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) RecG_wedge PF17191.4 EAX98890.1 - 0.2 11.3 0.8 16 5.0 0.3 2.2 1 1 1 2 2 2 0 RecG wedge domain DUF563 PF04577.14 EAX98891.1 - 3.1e-24 86.3 0.4 4.9e-24 85.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TrbI_Ftype PF09677.10 EAX98892.1 - 0.59 10.5 5.4 0.9 9.9 2.7 2.8 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) TPR_MLP1_2 PF07926.12 EAX98893.1 - 0.021 14.9 0.1 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX98893.1 - 0.085 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAX98893.1 - 0.39 10.7 9.4 0.1 12.5 2.4 2.6 3 1 0 3 3 3 0 Spo12 family DUF4795 PF16043.5 EAX98894.1 - 0.024 14.3 18.8 1.7 8.2 0.6 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAX98894.1 - 0.35 11.0 0.1 0.35 11.0 0.1 4.5 4 1 1 5 5 5 0 Phage tail repeat like TMP PF05017.14 EAX98896.1 - 0.14 12.8 1.8 37 5.6 0.1 3.4 3 0 0 3 3 3 0 TMP repeat Myb_DNA-binding PF00249.31 EAX98897.1 - 1.1e-24 86.3 1.0 1.6e-11 44.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98897.1 - 2.5e-17 62.9 4.7 1e-11 44.9 1.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98897.1 - 5.1e-05 23.3 1.3 0.0072 16.3 0.3 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX98897.1 - 0.0041 17.0 0.4 0.0041 17.0 0.4 2.7 2 1 1 3 3 3 1 Myb DNA-binding like DUF1660 PF07874.11 EAX98897.1 - 0.037 14.5 0.4 0.095 13.2 0.4 1.8 1 1 0 1 1 1 0 Prophage protein (DUF1660) NIF PF03031.18 EAX98897.1 - 0.04 13.7 2.6 0.1 12.4 2.6 1.7 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase P_proprotein PF01483.20 EAX98898.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase P-domain Gly_rich PF12810.7 EAX98899.1 - 3.5e-34 118.8 31.9 3.5e-34 118.8 31.9 2.3 2 0 0 2 2 2 1 Glycine rich protein Apt1 PF10351.9 EAX98899.1 - 0.00089 18.2 16.7 0.0012 17.8 16.7 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Furin-like_2 PF15913.5 EAX98899.1 - 0.0018 18.4 23.8 0.11 12.6 12.6 2.3 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich DUF2207 PF09972.9 EAX98899.1 - 0.042 12.6 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Utp14 PF04615.13 EAX98899.1 - 0.048 12.2 7.2 0.06 11.9 7.2 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 EAX98899.1 - 0.058 12.0 20.3 0.074 11.6 20.3 1.1 1 0 0 1 1 1 0 Macoilin family Syndecan PF01034.20 EAX98899.1 - 0.18 11.8 1.1 0.36 10.8 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EAX98899.1 - 0.24 12.3 0.9 0.59 11.1 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Menin PF05053.13 EAX98899.1 - 0.25 9.7 7.2 0.37 9.1 7.2 1.3 1 0 0 1 1 1 0 Menin SPX PF03105.19 EAX98899.1 - 0.26 11.2 21.4 0.36 10.7 21.4 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 EAX98899.1 - 0.87 8.2 7.6 1.3 7.6 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SDA1 PF05285.12 EAX98899.1 - 1.2 8.5 16.2 1.7 8.0 16.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4614 PF15391.6 EAX98899.1 - 2.4 8.1 27.6 5.5 7.0 27.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Hid1 PF12722.7 EAX98899.1 - 2.6 6.0 15.8 3.5 5.6 15.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 EAX98899.1 - 3.1 5.9 18.0 4.1 5.5 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family Orf78 PF06024.12 EAX98899.1 - 3.5 8.0 11.7 2.9e+02 1.8 11.7 2.6 1 1 0 1 1 1 0 Orf78 (ac78) Peroxin-3 PF04882.12 EAX98899.1 - 5.6 5.8 14.6 8.1 5.3 14.6 1.3 1 0 0 1 1 1 0 Peroxin-3 QWRF PF04484.12 EAX98899.1 - 6.8 6.3 16.7 9.1 5.9 16.7 1.1 1 0 0 1 1 1 0 QWRF family GREB1 PF15782.5 EAX98899.1 - 6.9 3.6 18.2 8.2 3.4 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PNISR PF15996.5 EAX98899.1 - 8.4 6.6 12.3 14 5.9 12.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 EAX98899.1 - 8.5 4.7 19.0 12 4.3 19.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 MULE PF10551.9 EAX98900.1 - 2.5e-10 40.6 0.2 6.3e-10 39.4 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAX98900.1 - 0.012 14.5 0.1 0.025 13.4 0.1 1.5 1 0 0 1 1 1 0 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAX98900.1 - 0.012 15.3 0.1 0.043 13.5 0.1 1.8 1 1 0 1 1 1 0 Transposase FAR1 PF03101.15 EAX98900.1 - 0.065 13.9 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain LRR_5 PF13306.6 EAX98902.1 - 1.4e-139 458.3 81.2 6.8e-35 119.8 7.1 3.7 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98902.1 - 7.2e-14 51.3 0.1 0.015 15.0 0.0 6.0 5 1 2 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EAX98902.1 - 0.0016 18.8 4.9 15 6.2 0.2 5.3 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) hSac2 PF12456.8 EAX98902.1 - 0.078 12.7 0.4 7.6 6.3 0.1 2.8 3 0 0 3 3 3 0 Inositol phosphatase DAP10 PF07213.11 EAX98903.1 - 0.00041 20.2 0.1 0.00064 19.6 0.1 1.4 1 0 0 1 1 1 1 DAP10 membrane protein EphA2_TM PF14575.6 EAX98903.1 - 0.13 13.1 2.3 0.28 12.1 2.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_5 PF13306.6 EAX98904.1 - 2.5e-10 40.4 6.7 4.1e-10 39.7 6.7 1.5 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX98904.1 - 6.7e-06 25.8 0.9 0.0036 17.0 0.3 2.1 1 1 1 2 2 2 2 Leucine rich repeat DUF4107 PF13389.6 EAX98907.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAX98908.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Myb_DNA-binding PF00249.31 EAX98910.1 - 3.6e-28 97.5 1.8 3.7e-14 52.6 1.6 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX98910.1 - 1.2e-23 83.1 1.4 7e-12 45.4 1.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX98910.1 - 4.2e-06 26.8 0.0 0.12 12.4 0.1 2.3 2 0 0 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EAX98910.1 - 0.0016 18.7 0.3 0.41 11.0 0.2 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 EAX98910.1 - 0.0022 17.9 0.5 0.4 10.6 0.4 2.4 2 0 0 2 2 2 1 Myb DNA-binding like DUF600 PF04634.12 EAX98910.1 - 0.066 13.3 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 SANT_DAMP1_like PF16282.5 EAX98910.1 - 0.11 12.7 0.9 0.43 10.8 0.6 2.2 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Tho1_MOS11_C PF18592.1 EAX98910.1 - 0.12 12.2 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Myb_DNA-bind_4 PF13837.6 EAX98910.1 - 2.1 8.8 7.9 1.1 9.6 3.8 2.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Complex1_LYR PF05347.15 EAX98911.1 - 0.0021 18.1 0.1 0.0046 17.0 0.1 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) ssDNA_DBD PF18333.1 EAX98912.1 - 0.0069 16.5 0.1 0.022 14.9 0.1 1.8 1 0 0 1 1 1 1 Non-canonical single-stranded DNA-binding domain Mob1_phocein PF03637.17 EAX98912.1 - 0.033 14.2 2.3 0.076 13.0 1.3 1.9 2 0 0 2 2 2 0 Mob1/phocein family SpoVS PF04232.12 EAX98913.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) EB1 PF03271.17 EAX98917.1 - 3.1e-05 24.1 4.9 8.3e-05 22.7 0.0 3.1 3 1 0 3 3 3 1 EB1-like C-terminal motif VRP1 PF03538.14 EAX98917.1 - 0.00037 20.0 0.9 0.15 11.5 0.2 2.3 1 1 1 2 2 2 2 Salmonella virulence plasmid 28.1kDa A protein Phage_TAC_12 PF12363.8 EAX98917.1 - 0.019 15.4 3.6 0.059 13.8 3.6 1.8 1 1 0 1 1 1 0 Phage tail assembly chaperone protein, TAC SpoIISA_toxin PF14171.6 EAX98917.1 - 0.029 14.1 3.8 0.035 13.8 3.8 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HicB-like_2 PF15970.5 EAX98917.1 - 0.3 11.3 1.8 0.59 10.3 1.8 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system zf-ZPR1 PF03367.13 EAX98917.1 - 0.58 10.0 4.8 0.49 10.2 3.2 1.6 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF2205 PF10224.9 EAX98919.1 - 0.23 11.5 2.1 0.5 10.4 2.1 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Peptidase_C1 PF00112.23 EAX98920.1 - 5.6e-50 170.4 0.8 9.2e-50 169.7 0.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAX98920.1 - 0.0087 14.9 2.0 0.076 11.8 0.3 2.4 3 0 0 3 3 3 2 Peptidase C1-like family Profilin PF00235.19 EAX98921.1 - 8.9e-26 90.6 0.0 9.8e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Profilin TBCC PF07986.12 EAX98921.1 - 0.023 14.4 0.3 0.032 13.9 0.3 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C Ank_2 PF12796.7 EAX98922.1 - 4.4e-11 43.2 2.3 0.0093 16.5 0.3 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX98922.1 - 6.2e-10 38.5 0.1 0.0059 17.0 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAX98922.1 - 1.4e-06 28.7 0.2 2.1e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98922.1 - 9.4e-06 25.5 7.7 9.4e-06 25.5 7.7 4.1 2 2 3 5 5 5 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX98922.1 - 0.00041 20.6 0.3 5.5 7.4 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX98922.1 - 0.00079 19.8 0.0 1.6 9.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat LRR_6 PF13516.6 EAX98923.1 - 0.036 14.1 0.1 12 6.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Pre-PUA PF17832.1 EAX98923.1 - 0.085 13.6 1.0 15 6.3 0.2 3.0 2 0 0 2 2 2 0 Pre-PUA-like domain LRR_4 PF12799.7 EAX98923.1 - 8.3 7.0 22.8 56 4.4 0.0 7.2 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) Erf4 PF10256.9 EAX98924.1 - 0.019 15.1 0.5 0.05 13.7 0.3 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Coatomer_E PF04733.14 EAX98924.1 - 0.024 14.0 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit Rep_fac_C PF08542.11 EAX98924.1 - 0.11 13.0 0.2 0.24 11.8 0.2 1.5 1 1 0 1 1 1 0 Replication factor C C-terminal domain TPR_19 PF14559.6 EAX98924.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ER_lumen_recept PF00810.18 EAX98925.1 - 1.2e-47 162.5 15.6 1.8e-47 161.9 15.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF4149 PF13664.6 EAX98925.1 - 0.027 14.8 0.8 0.027 14.8 0.8 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) LCCL PF03815.19 EAX98926.1 - 0.00025 21.1 0.3 0.43 10.7 0.1 2.3 2 0 0 2 2 2 2 LCCL domain Rxt3 PF08642.10 EAX98926.1 - 0.11 13.3 0.0 0.3 11.8 0.0 1.8 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Thioredoxin_6 PF13848.6 EAX98927.1 - 5.2e-05 23.2 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EAX98927.1 - 7.2e-05 22.7 0.0 0.00022 21.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Pkinase PF00069.25 EAX98928.1 - 1.2e-54 185.4 0.2 1.7e-54 184.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98928.1 - 1.2e-19 70.6 0.0 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAX98928.1 - 0.00079 19.1 0.9 0.0018 17.9 0.9 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EAX98928.1 - 0.0027 17.3 0.3 0.012 15.2 0.0 1.9 1 1 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 EAX98928.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX98928.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family CEP19 PF14933.6 EAX98929.1 - 9.7 6.5 10.8 0.7 10.2 1.0 2.5 1 1 1 2 2 2 0 CEP19-like protein DUF2981 PF11200.8 EAX98930.1 - 7.3 6.2 10.6 9.8 5.8 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) POR_N PF01855.19 EAX98931.1 - 5.6e-74 248.8 0.7 9.7e-74 248.0 0.7 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EAX98931.1 - 4.1e-30 105.2 0.0 8.2e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 EAX98931.1 - 3e-11 42.7 19.1 4e-06 26.4 1.2 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain TPP_enzyme_C PF02775.21 EAX98931.1 - 1.3e-10 41.2 0.1 4.5e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 EAX98931.1 - 2.1e-10 41.0 21.8 6e-10 39.6 6.2 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAX98931.1 - 1.4e-09 37.9 20.9 7.7e-08 32.3 9.2 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAX98931.1 - 1.7e-09 38.4 9.5 0.00025 21.9 3.1 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain PFOR_II PF17147.4 EAX98931.1 - 1.9e-08 34.5 0.0 6e-08 32.9 0.0 1.9 2 0 0 2 2 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_6 PF12837.7 EAX98931.1 - 3.4e-07 30.0 24.5 1.6e-05 24.8 4.4 3.6 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 EAX98931.1 - 3.5e-07 30.3 13.2 6.3e-06 26.3 11.1 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 EAX98931.1 - 9.8e-07 28.8 10.0 6.6e-06 26.2 10.0 2.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain EKR PF10371.9 EAX98931.1 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_2 PF12797.7 EAX98931.1 - 7.3e-06 25.8 21.2 0.0011 18.9 3.3 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 EAX98931.1 - 3.4e-05 24.3 5.5 3.4e-05 24.3 5.5 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAX98931.1 - 0.0003 21.2 8.3 0.0003 21.2 8.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 EAX98931.1 - 0.00048 20.3 3.0 0.51 10.6 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAX98931.1 - 0.003 18.0 19.1 0.022 15.2 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_15 PF13459.6 EAX98931.1 - 0.065 14.0 2.2 5.2 7.9 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF4279 PF14106.6 EAX98931.1 - 0.08 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Fer4_22 PF17179.4 EAX98931.1 - 6.2 7.7 16.8 0.28 12.1 0.2 2.8 3 0 0 3 3 2 0 4Fe-4S dicluster domain DUF3447 PF11929.8 EAX98933.1 - 9.7e-39 131.2 6.1 9.7e-39 131.2 6.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98933.1 - 3.1e-38 129.7 6.3 8.5e-11 42.2 0.1 7.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98933.1 - 7e-35 119.5 12.1 2.1e-18 66.7 2.6 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98933.1 - 3.8e-34 115.6 5.1 5.4e-09 36.1 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX98933.1 - 6e-28 93.8 7.9 4.8e-07 29.6 0.1 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAX98933.1 - 8.9e-27 92.8 6.3 4.6e-11 42.7 0.1 5.4 4 1 3 7 7 7 4 Ankyrin repeats (many copies) PH_8 PF15409.6 EAX98933.1 - 0.05 13.9 0.4 35 4.8 0.0 4.0 2 1 1 4 4 4 0 Pleckstrin homology domain Cation_ATPase_N PF00690.26 EAX98933.1 - 0.053 13.2 1.0 53 3.6 0.0 3.7 3 1 1 4 4 4 0 Cation transporter/ATPase, N-terminus PK_C PF02887.16 EAX98934.1 - 0.0083 16.3 4.9 19 5.5 4.1 4.0 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HTH_24 PF13412.6 EAX98934.1 - 0.42 10.2 4.4 23 4.6 0.2 3.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding KAAG1 PF15354.6 EAX98934.1 - 3.7 8.2 11.0 4.2 8.0 2.2 3.1 1 1 2 3 3 3 0 Kidney-associated antigen 1 HMMR_N PF15905.5 EAX98935.1 - 0.025 14.1 2.6 0.043 13.3 2.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 EAX98935.1 - 0.062 12.2 1.6 0.09 11.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ING PF12998.7 EAX98935.1 - 0.071 13.7 0.7 0.071 13.7 0.7 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fez1 PF06818.15 EAX98935.1 - 0.091 13.2 1.3 0.12 12.9 0.6 1.5 2 0 0 2 2 2 0 Fez1 GAT PF03127.14 EAX98935.1 - 0.1 12.9 5.2 0.6 10.5 1.9 3.1 3 1 0 3 3 3 0 GAT domain SapB_2 PF03489.17 EAX98935.1 - 0.11 12.7 0.2 0.47 10.6 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 2 Cnd1 PF12717.7 EAX98935.1 - 0.19 11.8 7.9 1.6 8.8 3.3 3.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FAM76 PF16046.5 EAX98935.1 - 0.19 11.0 1.4 0.29 10.5 1.4 1.3 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 EAX98935.1 - 0.34 11.0 9.6 0.034 14.1 4.7 2.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EAX98935.1 - 1.1 9.4 7.4 1.2 9.3 1.2 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CDC27 PF09507.10 EAX98936.1 - 1 8.7 48.6 1.5 8.2 48.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 EAX98936.1 - 6.5 6.6 35.4 8.5 6.3 35.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_1 PF00036.32 EAX98937.1 - 4.6e-16 57.1 5.1 1.1e-07 30.9 0.7 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EAX98937.1 - 5.8e-16 58.7 3.8 3.8e-07 30.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX98937.1 - 3.2e-14 51.6 3.2 4.6e-07 29.2 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EAX98937.1 - 2.8e-10 39.9 1.6 2.7e-05 23.9 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EAX98937.1 - 6e-08 32.9 0.2 0.00018 21.8 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EAX98937.1 - 1.3e-07 30.8 3.8 0.00071 19.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EAX98937.1 - 0.014 15.3 0.6 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EAX98937.1 - 0.028 14.4 0.3 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein Armet PF10208.9 EAX98937.1 - 0.032 14.2 0.0 0.15 11.9 0.0 1.9 2 1 0 2 2 2 0 Degradation arginine-rich protein for mis-folding SurA_N_2 PF13623.6 EAX98937.1 - 0.047 13.5 0.1 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 EAX98937.1 - 0.066 13.5 0.1 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TRCF PF03461.15 EAX98937.1 - 0.12 12.8 0.0 5.5 7.4 0.0 2.2 2 0 0 2 2 2 0 TRCF domain 14-3-3 PF00244.20 EAX98938.1 - 3.5e-61 206.5 5.8 4.3e-61 206.2 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EAX98938.1 - 0.017 15.4 0.4 0.039 14.3 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat IpaB_EvcA PF03278.13 EAX98938.1 - 0.03 14.0 1.1 0.083 12.6 0.5 1.9 1 1 1 2 2 2 0 IpaB/EvcA family DUF305 PF03713.13 EAX98938.1 - 0.088 13.0 0.7 0.4 10.8 0.4 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF305) Pkinase PF00069.25 EAX98939.1 - 3e-69 233.3 0.0 4.4e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX98939.1 - 4.3e-42 144.2 0.0 6.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX98939.1 - 2e-05 24.1 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAX98939.1 - 0.003 16.6 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX98939.1 - 0.0032 17.4 0.1 0.0056 16.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX98939.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EAX98939.1 - 0.016 14.8 0.3 0.033 13.8 0.3 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase NYN PF01936.18 EAX98939.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 NYN domain ABC1 PF03109.16 EAX98939.1 - 0.16 12.1 1.3 0.51 10.5 1.3 1.8 1 1 0 1 1 1 0 ABC1 family Gly_rich PF12810.7 EAX98940.1 - 2e-29 103.2 18.9 2.5e-29 102.9 18.9 1.1 1 0 0 1 1 1 1 Glycine rich protein AMP-binding PF00501.28 EAX98941.1 - 3.4e-53 180.8 0.0 4.8e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TypeIII_RM_meth PF12564.8 EAX98941.1 - 0.91 9.7 6.5 0.24 11.6 0.9 2.7 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit Ank_2 PF12796.7 EAX98942.1 - 1.7e-43 147.1 12.2 3.1e-12 46.9 0.1 5.3 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98942.1 - 1.5e-40 135.9 5.6 2.2e-05 24.7 0.1 9.0 8 1 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAX98942.1 - 2.9e-40 136.1 8.4 1.1e-09 38.6 0.0 7.8 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98942.1 - 7.1e-32 109.1 7.3 4.4e-09 36.4 0.0 6.4 4 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98942.1 - 3.9e-29 97.4 16.4 0.00027 21.1 0.0 9.9 11 0 0 11 11 11 7 Ankyrin repeat DUF3447 PF11929.8 EAX98942.1 - 0.00012 21.9 0.9 0.00012 21.9 0.9 4.0 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Mic1 PF07035.12 EAX98942.1 - 0.0081 15.9 2.3 0.069 12.9 0.1 2.8 3 1 0 3 3 3 1 Colon cancer-associated protein Mic1-like ATP-grasp_5 PF13549.6 EAX98943.1 - 3.1e-55 187.0 0.0 5.1e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EAX98943.1 - 1.1e-33 116.0 0.0 1.8e-32 112.1 0.1 2.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EAX98943.1 - 1.4e-09 38.5 0.0 6.5e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain Phi-29_GP3 PF05435.11 EAX98944.1 - 0.041 13.4 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Plant_NMP1 PF06694.11 EAX98944.1 - 0.15 11.1 1.0 0.29 10.2 1.0 1.5 1 1 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Ank PF00023.30 EAX98945.1 - 3.7e-44 147.3 1.0 1.1e-07 31.9 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 EAX98945.1 - 1.8e-42 143.8 14.5 1.2e-15 57.9 0.3 5.7 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98945.1 - 5.7e-42 141.2 11.0 7.2e-11 42.1 0.2 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX98945.1 - 2.9e-40 136.1 6.2 2.9e-40 136.1 6.2 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98945.1 - 1.9e-39 133.5 7.2 2.8e-12 46.9 0.1 8.2 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98945.1 - 6.8e-30 99.8 8.0 3.6e-05 23.8 0.0 9.5 11 0 0 11 11 11 5 Ankyrin repeat DHBP_synthase PF00926.19 EAX98945.1 - 0.00047 19.7 1.2 0.92 9.0 0.0 3.7 2 1 0 3 3 3 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ATP13 PF12921.7 EAX98945.1 - 0.64 9.9 7.3 0.26 11.1 2.5 2.8 2 1 1 3 3 3 0 Mitochondrial ATPase expression HALZ PF02183.18 EAX98946.1 - 0.023 14.9 5.2 0.89 9.8 0.7 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Epsilon_antitox PF08998.11 EAX98946.1 - 0.068 13.4 1.4 0.22 11.8 1.3 1.9 1 1 0 1 1 1 0 Bacterial epsilon antitoxin DUF3492 PF11997.8 EAX98946.1 - 0.086 12.6 4.4 0.031 14.0 2.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) APAF1_C PF17908.1 EAX98946.1 - 0.26 11.3 6.8 1.7 8.6 0.1 3.2 2 1 1 3 3 3 0 APAF-1 helical domain PMC2NT PF08066.12 EAX98946.1 - 0.49 11.1 7.3 1.4 9.6 0.1 3.1 2 1 1 3 3 3 0 PMC2NT (NUC016) domain TMF_TATA_bd PF12325.8 EAX98946.1 - 2.5 8.4 13.6 3.7 7.8 8.0 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 EAX98946.1 - 9.9 6.6 9.8 0.69 10.3 1.5 3.0 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF2691 PF10903.8 EAX98947.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) FAM35_C PF15793.5 EAX98947.1 - 0.071 12.5 0.1 0.089 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein family FAM35, C-terminal DUF4473 PF14747.6 EAX98947.1 - 0.14 12.7 2.2 2 9.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF563 PF04577.14 EAX98948.1 - 4.8e-28 98.7 0.2 7.1e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) zf-C3Hc3H PF13891.6 EAX98949.1 - 0.0015 18.9 1.5 0.0023 18.3 1.1 1.5 2 0 0 2 2 2 1 Potential DNA-binding domain PSP PF04046.16 EAX98951.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX98952.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX98954.1 - 6e-27 93.5 29.7 2.1e-23 82.2 7.4 5.5 4 1 1 5 5 4 2 Phage tail repeat like DUF4116 PF13475.6 EAX98954.1 - 0.04 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAX98954.1 - 0.16 11.7 1.9 6.6 6.4 1.3 2.6 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3417 PF11897.8 EAX98954.1 - 0.28 11.7 0.0 0.28 11.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF240 PF03086.14 EAX98954.1 - 0.82 9.6 6.1 3.1 7.7 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF240) PRA-PH PF01503.17 EAX98955.1 - 0.12 12.8 3.5 8 7.0 4.2 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Sec7 PF01369.20 EAX98956.1 - 5.9e-63 211.9 5.8 1.8e-62 210.3 0.1 3.8 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 EAX98956.1 - 6.1e-17 61.3 0.4 1.2e-15 57.1 0.3 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 EAX98956.1 - 1.4e-06 28.3 0.1 1.4e-06 28.3 0.1 5.3 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal BAR_2 PF10455.9 EAX98956.1 - 0.0072 15.5 0.4 0.015 14.5 0.4 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3320 PF11784.8 EAX98956.1 - 0.26 11.3 0.5 1.6 8.7 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Rad50_zn_hook PF04423.14 EAX98956.1 - 3.4 7.6 4.9 5.3 7.0 0.2 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF45 PF01863.17 EAX98958.1 - 0.043 13.8 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ocnus PF05005.15 EAX98958.1 - 0.11 12.6 0.0 0.5 10.5 0.0 1.9 1 1 1 2 2 2 0 Janus/Ocnus family (Ocnus) RTP1_C1 PF10363.9 EAX98961.1 - 0.0034 17.6 0.4 1 9.6 0.1 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EAX98961.1 - 0.6 10.7 3.2 3.9 8.2 0.2 3.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region KilA-N PF04383.13 EAX98963.1 - 5.8e-07 29.3 0.1 1.3e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX98963.1 - 0.029 13.8 0.4 0.056 12.9 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3839 PF12943.7 EAX98964.1 - 5.7e-133 441.8 13.6 1.7e-132 440.2 13.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX98964.1 - 0.061 13.8 2.9 0.072 13.5 0.7 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX98964.1 - 0.096 13.2 7.2 0.67 10.4 0.2 2.9 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MitMem_reg PF13012.6 EAX98964.1 - 0.25 11.8 1.3 2 8.8 0.0 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Trypan_PARP PF05887.11 EAX98965.1 - 0.005 16.8 7.4 0.0077 16.2 7.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX98966.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX98966.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain rve PF00665.26 EAX98967.1 - 8.9e-13 48.5 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EAX98967.1 - 2.1e-07 30.6 0.3 4.6e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2856 PF11043.8 EAX98967.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) UCH PF00443.29 EAX98968.1 - 2.3e-67 227.2 0.2 1.3e-65 221.5 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX98968.1 - 3.5e-09 37.1 0.1 3.5e-09 37.1 0.1 4.7 4 2 0 4 4 4 1 DUSP domain Aminotran_1_2 PF00155.21 EAX98969.1 - 2.4e-58 198.1 0.0 2.7e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pur_DNA_glyco PF02245.16 EAX98971.1 - 1.7e-46 157.8 0.0 1.4e-45 154.9 0.0 1.9 1 1 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Metallophos PF00149.28 EAX98972.1 - 1.7e-26 94.0 0.0 2.9e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX98972.1 - 0.0096 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LRR_8 PF13855.6 EAX98973.1 - 4.8e-14 51.9 22.4 0.00017 21.3 11.7 4.2 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAX98973.1 - 1.9e-10 40.8 25.5 7.3e-05 23.1 8.7 5.4 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX98973.1 - 7.4e-05 22.3 4.0 0.058 12.9 1.0 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EAX98973.1 - 0.0015 18.8 21.1 0.21 12.3 0.9 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 EAX98973.1 - 0.0058 16.6 29.0 0.14 12.3 3.0 6.0 7 0 0 7 7 7 3 Leucine Rich repeat TUTF7_u4 PF16631.5 EAX98973.1 - 2 9.1 7.5 4.9 7.9 7.5 1.6 1 0 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 TMEM156 PF15106.6 EAX98974.1 - 1.1 8.7 5.0 1.5 8.2 5.0 1.3 1 1 0 1 1 1 0 TMEM156 protein family Orf78 PF06024.12 EAX98975.1 - 1.7e-05 25.1 6.5 0.00054 20.2 1.1 2.5 2 0 0 2 2 2 2 Orf78 (ac78) DUF1634 PF07843.11 EAX98975.1 - 0.015 15.3 1.2 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) SMP_2 PF10144.9 EAX98975.1 - 4 7.1 5.9 0.29 10.8 0.5 1.8 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Renin_r PF07850.14 EAX98975.1 - 7.6 7.2 11.2 0.43 11.2 3.7 2.3 1 1 0 2 2 2 0 Renin receptor-like protein PAS_9 PF13426.7 EAX98976.1 - 1.6e-08 34.7 1.0 3.3e-08 33.7 0.5 1.8 2 0 0 2 2 2 1 PAS domain Guanylate_cyc PF00211.20 EAX98976.1 - 9.6e-07 28.6 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 EAX98976.1 - 9.5e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX98976.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAX98976.1 - 0.00011 22.4 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EAX98976.1 - 0.035 14.4 0.0 0.085 13.2 0.0 1.7 2 0 0 2 2 2 0 PAS fold DDE_1 PF03184.19 EAX98977.1 - 4.5e-16 59.0 0.0 9.2e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 EAX98978.1 - 1.2e-42 143.5 0.0 1.7e-16 59.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX98978.1 - 2e-10 40.4 0.0 0.0011 18.5 0.0 3.4 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAX98978.1 - 1.6e-05 24.9 0.0 0.14 12.2 0.0 3.5 3 0 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 EAX98978.1 - 0.00056 19.7 0.0 0.34 10.8 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EAX98978.1 - 0.00069 19.6 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAX98978.1 - 0.0019 18.2 0.0 0.21 11.6 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Ank_4 PF13637.6 EAX98980.1 - 5e-33 113.1 13.5 8.3e-08 32.6 0.4 7.3 3 1 5 9 9 9 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98980.1 - 9e-29 99.9 17.4 9.1e-09 35.8 1.1 6.1 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAX98980.1 - 1.2e-26 91.9 11.6 0.0023 18.3 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 EAX98980.1 - 1.6e-24 85.6 3.1 1.6e-24 85.6 3.1 4.5 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX98980.1 - 7e-22 77.2 8.3 4.7e-06 26.8 0.2 5.9 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98980.1 - 1.8e-21 73.9 12.9 0.0079 16.6 0.3 9.4 10 0 0 10 10 10 6 Ankyrin repeat RL PF17797.1 EAX98980.1 - 1.2 9.2 10.0 3.9 7.5 0.3 3.6 4 0 0 4 4 4 0 RL domain BTB PF00651.31 EAX98981.1 - 1.4e-19 70.4 0.1 3.6e-14 52.9 0.4 2.4 2 0 0 2 2 2 2 BTB/POZ domain ubiquitin PF00240.23 EAX98982.1 - 0.011 15.5 0.1 0.033 13.9 0.0 1.9 2 1 0 2 2 2 0 Ubiquitin family Rad60-SLD PF11976.8 EAX98982.1 - 0.035 13.9 0.3 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Chordopox_A13L PF05961.11 EAX98983.1 - 0.016 15.5 2.6 0.031 14.5 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3899 PF13038.6 EAX98983.1 - 0.027 15.0 1.1 0.6 10.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Ost5 PF05251.12 EAX98983.1 - 0.075 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 DUF5534 PF17686.1 EAX98983.1 - 0.083 13.2 7.0 0.56 10.4 1.4 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5534) Vpu PF00558.19 EAX98983.1 - 0.22 11.3 5.3 0.084 12.7 1.3 2.3 2 0 0 2 2 2 0 Vpu protein FeoB_associated PF12669.7 EAX98983.1 - 1.1 9.7 6.6 2.3 8.7 6.6 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TRP PF06011.12 EAX98984.1 - 5.2e-07 28.8 3.4 6.7e-07 28.4 3.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Peptidase_U57 PF05582.12 EAX98984.1 - 4 6.6 6.6 2.5 7.3 4.7 1.5 2 0 0 2 2 2 0 YabG peptidase U57 FAM176 PF14851.6 EAX98984.1 - 4.1 7.1 6.4 6.3 6.4 6.4 1.2 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 EAX98987.1 - 2.1e-10 41.2 0.0 2.9e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX98987.1 - 1.8e-07 30.8 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EAX98987.1 - 0.0039 16.1 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class U71 PF17474.2 EAX98987.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tegument protein UL11 homolog SbcCD_C PF13558.6 EAX98987.1 - 0.3 11.4 1.0 8 6.8 1.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CRCB PF02537.15 EAX98988.1 - 2.7e-17 62.8 7.0 3.4e-17 62.5 7.0 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) YrhC PF14143.6 EAX98988.1 - 0.00031 20.8 1.7 0.015 15.4 0.1 2.4 2 0 0 2 2 2 1 YrhC-like protein DUF4149 PF13664.6 EAX98988.1 - 0.00096 19.4 0.4 0.0039 17.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MIG-14_Wnt-bd PF06664.12 EAX98988.1 - 0.0046 16.2 0.5 0.0064 15.8 0.5 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Frag1 PF10277.9 EAX98988.1 - 0.014 14.9 0.7 0.015 14.8 0.7 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Na_H_antiport_3 PF07399.11 EAX98988.1 - 0.061 12.2 1.4 0.051 12.5 0.5 1.4 1 1 0 1 1 1 0 Putative Na+/H+ antiporter DC_STAMP PF07782.13 EAX98988.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein ABC2_membrane_3 PF12698.7 EAX98988.1 - 0.16 11.0 4.3 0.26 10.4 4.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RseC_MucC PF04246.12 EAX98988.1 - 0.26 11.2 1.4 0.71 9.8 0.1 2.1 1 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DHHC PF01529.20 EAX98988.1 - 0.37 10.9 2.6 0.66 10.1 2.6 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase ECF_trnsprt PF12822.7 EAX98988.1 - 5.7 7.0 8.1 28 4.7 8.1 2.2 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Ank_2 PF12796.7 EAX98990.1 - 5.8e-38 129.3 16.2 3.3e-15 56.4 0.7 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98990.1 - 3.4e-26 91.3 1.4 3.5e-11 43.4 0.0 5.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98990.1 - 5.5e-20 69.3 4.6 0.00012 22.2 0.1 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAX98990.1 - 1.2e-16 60.5 0.2 5.5e-08 32.9 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX98990.1 - 2.2e-16 59.5 3.1 0.00084 19.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 EAX98990.1 - 0.028 14.4 1.4 0.028 14.4 1.4 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF3447) DUF870 PF05912.11 EAX98990.1 - 0.47 10.5 5.7 3.7 7.6 0.4 2.7 1 1 2 3 3 3 0 Caenorhabditis elegans protein of unknown function (DUF870) Ank_2 PF12796.7 EAX98991.1 - 7.3e-20 71.3 5.7 4.1e-14 52.9 1.7 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98991.1 - 7.3e-17 61.5 1.2 1.3e-11 44.7 0.5 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98991.1 - 9.3e-13 47.1 0.4 0.002 18.4 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EAX98991.1 - 1.3e-10 41.2 0.9 0.0069 16.8 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX98991.1 - 3.8e-10 39.8 2.9 8.8e-06 25.9 0.0 3.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) NOP5NT PF08156.13 EAX98991.1 - 0.15 12.5 2.1 0.45 10.9 0.9 2.5 2 1 1 3 3 3 0 NOP5NT (NUC127) domain HSP70 PF00012.20 EAX98992.1 - 1.1e-99 334.3 3.6 1.1e-99 334.3 3.6 2.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EAX98992.1 - 1.3e-05 24.1 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FTA4 PF13093.6 EAX98992.1 - 0.0081 16.1 2.8 0.014 15.3 1.3 2.1 2 0 0 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4251 PF14059.6 EAX98992.1 - 0.48 10.4 4.4 0.73 9.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4251) DUF3447 PF11929.8 EAX98993.1 - 4.5e-34 116.2 4.3 4.5e-34 116.2 4.3 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX98993.1 - 5.5e-23 81.0 0.4 2.2e-07 31.3 0.0 5.8 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX98993.1 - 2.2e-20 73.0 2.0 2.8e-13 50.3 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX98993.1 - 7e-17 61.3 0.5 1.1e-07 32.0 0.2 3.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX98993.1 - 7.1e-15 54.7 0.0 0.00016 22.0 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EAX98993.1 - 6.7e-14 50.6 0.3 0.0018 18.6 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 EAX98994.1 - 5.9e-28 97.3 0.0 9.7e-10 38.9 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX98994.1 - 5.2e-19 68.4 1.1 4.9e-08 33.4 0.1 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX98994.1 - 9.7e-19 67.2 0.3 2.9e-06 27.4 0.0 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX98994.1 - 3.3e-17 60.8 4.1 0.01 16.3 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EAX98994.1 - 1.8e-12 47.1 0.2 0.008 16.6 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Peptidase_S28 PF05577.12 EAX98995.1 - 2.3e-64 217.8 1.3 1.7e-41 142.5 0.1 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EAX98995.1 - 4.5e-09 35.5 0.2 7.1e-09 34.8 0.2 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 EAX98995.1 - 2.8e-05 23.7 0.0 9e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAX98995.1 - 0.00021 21.0 0.1 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX98995.1 - 0.0044 16.3 0.0 0.0097 15.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EAX98995.1 - 0.017 14.7 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF2920 PF11144.8 EAX98995.1 - 0.019 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) GlcNAc PF11397.8 EAX98996.1 - 0.19 11.2 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) TMP PF05017.14 EAX98998.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX98999.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAX99000.1 - 1.2e-34 118.0 3.8 1.2e-34 118.0 3.8 4.0 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99000.1 - 4.8e-23 81.6 10.1 9.4e-13 48.6 2.6 4.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99000.1 - 2.9e-20 72.4 8.4 2e-08 34.6 0.1 6.0 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99000.1 - 6.8e-15 54.8 9.8 1.2e-05 25.5 0.3 5.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAX99000.1 - 3.6e-13 48.4 13.1 3.7e-05 23.8 0.2 7.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EAX99000.1 - 2.1e-12 47.0 4.6 1.2e-08 35.1 0.5 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) ATP13 PF12921.7 EAX99000.1 - 0.14 12.0 2.4 0.56 10.1 1.2 2.3 1 1 1 2 2 2 0 Mitochondrial ATPase expression UBX PF00789.20 EAX99001.1 - 1.4e-07 31.6 0.2 2.7e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EAX99001.1 - 0.014 15.6 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like UCH PF00443.29 EAX99002.1 - 1e-45 156.3 0.1 2.5e-45 155.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX99002.1 - 1.2e-14 54.6 3.7 2.3e-07 30.7 0.1 3.3 1 1 2 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX99002.1 - 2.4e-12 47.3 3.7 4.6e-12 46.4 0.0 2.7 2 0 0 2 2 2 1 DUSP domain Erv26 PF04148.13 EAX99003.1 - 0.00098 19.0 3.4 0.12 12.2 2.3 2.1 1 1 1 2 2 2 2 Transmembrane adaptor Erv26 DUF1858 PF08984.11 EAX99004.1 - 0.026 14.7 0.9 0.24 11.6 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1858) Beach PF02138.18 EAX99005.1 - 2.5e-53 181.2 1.9 1.1e-52 179.2 1.9 2.2 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAX99005.1 - 4.7e-14 52.3 5.7 9.6e-14 51.3 5.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAX99005.1 - 0.00064 19.8 3.9 0.00081 19.4 0.7 3.0 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Smg4_UPF3 PF03467.15 EAX99005.1 - 0.027 14.5 0.2 0.076 13.0 0.2 1.7 1 0 0 1 1 1 0 Smg-4/UPF3 family EPOP PF15223.6 EAX99005.1 - 0.099 12.0 2.5 0.18 11.1 2.5 1.3 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein TAF PF02969.17 EAX99005.1 - 0.15 12.2 0.4 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) DUF4625 PF15418.6 EAX99006.1 - 0.0029 17.9 0.1 0.029 14.6 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4625) PolyA_pol PF01743.20 EAX99007.1 - 4.2e-22 78.9 0.1 8.4e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAX99007.1 - 4.3e-13 48.8 0.2 9.8e-13 47.7 0.2 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A GED PF02212.18 EAX99007.1 - 0.0022 18.1 1.2 0.0047 17.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain Aminoglyc_resit PF10706.9 EAX99007.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Med15_fungi PF05397.12 EAX99007.1 - 0.02 15.2 0.5 0.11 12.8 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 Pkinase PF00069.25 EAX99008.1 - 5e-60 203.1 0.0 6.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99008.1 - 7.6e-40 136.8 0.0 9.6e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99008.1 - 1.8e-08 34.0 0.0 5.5e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Kinase-like DUF1910 PF08928.10 EAX99008.1 - 0.036 14.1 0.2 0.075 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) FERM_M PF00373.18 EAX99009.1 - 0.0013 19.1 0.0 18 5.8 0.0 5.1 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 EAX99009.1 - 0.0085 16.0 0.0 1 9.3 0.0 4.0 3 0 0 3 3 3 1 FERM N-terminal domain EF-hand_14 PF17959.1 EAX99009.1 - 0.025 14.9 0.7 0.92 9.9 0.0 4.2 3 0 0 3 3 3 0 EF-hand domain Snapin_Pallidin PF14712.6 EAX99009.1 - 4.5 7.8 7.4 1 9.8 0.1 4.0 3 0 0 3 3 3 0 Snapin/Pallidin PRA-PH PF01503.17 EAX99010.1 - 0.17 12.3 2.5 10 6.6 3.5 2.7 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase GPS2_interact PF15784.5 EAX99011.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX99011.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX99013.1 - 2.5e-94 315.3 8.5 2.8e-94 315.1 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAX99015.1 - 4.3e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 Poxvirus A32 protein DUF4107 PF13389.6 EAX99016.1 - 3.5e-73 245.1 4.3 4.1e-73 244.9 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX99016.1 - 0.17 10.2 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Lipoxygenase Metallophos PF00149.28 EAX99018.1 - 2.1e-29 103.5 0.1 2.7e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L18 PF17135.4 EAX99018.1 - 0.27 10.6 0.0 0.51 9.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e TTL PF03133.15 EAX99019.1 - 8.2e-70 235.2 1.5 1.2e-69 234.7 1.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX99019.1 - 5.6e-13 48.7 0.3 3.8e-05 23.1 0.0 3.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX99019.1 - 4.5e-08 32.7 0.0 0.0059 15.9 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX99019.1 - 0.011 15.8 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.11 EAX99019.1 - 0.033 13.8 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 EAX99019.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Porin_6 PF16939.5 EAX99019.1 - 0.12 11.4 0.6 3 6.9 0.1 2.4 3 0 0 3 3 3 0 Putative porin Tubulin PF00091.25 EAX99020.1 - 1.7e-69 234.0 0.0 2.6e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAX99020.1 - 1.1e-38 132.3 0.0 1.8e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAX99020.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAX99020.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAX99020.1 - 0.037 13.2 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Glyco_hydro_38 PF18438.1 EAX99021.1 - 0.63 10.1 6.4 0.5 10.4 0.9 3.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Sel1 PF08238.12 EAX99022.1 - 1.2e-49 165.5 56.2 1.4e-06 28.7 0.0 21.1 24 0 0 24 24 24 14 Sel1 repeat TPR_16 PF13432.6 EAX99022.1 - 0.00036 21.1 17.1 1.2 9.9 1.8 8.6 10 0 0 10 10 10 2 Tetratricopeptide repeat UPF0004 PF00919.20 EAX99022.1 - 0.001 19.1 0.6 0.038 14.0 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized protein family UPF0004 Fis1_TPR_N PF14852.6 EAX99022.1 - 0.015 15.0 0.1 31 4.3 0.0 4.2 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat TPR_17 PF13431.6 EAX99022.1 - 0.24 11.9 26.6 1.5 9.4 0.4 10.9 10 4 3 14 14 14 0 Tetratricopeptide repeat PPR_long PF17177.4 EAX99022.1 - 0.26 10.6 6.1 6.7 6.0 0.0 3.8 3 1 1 4 4 4 0 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EAX99022.1 - 0.85 10.6 15.1 55 5.0 0.0 8.3 10 2 2 12 12 12 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EAX99023.1 - 3.7e-10 39.9 0.0 2.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAX99023.1 - 5.1e-06 25.9 0.0 1.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX99023.1 - 0.0024 18.5 0.0 0.0039 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EAX99023.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.18 EAX99023.1 - 0.076 12.6 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Myb_DNA-binding PF00249.31 EAX99025.1 - 0.00015 21.9 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99025.1 - 0.00086 19.5 0.2 0.005 17.1 0.2 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain YEATS PF03366.16 EAX99026.1 - 1.6e-20 72.8 0.2 2.9e-20 72.0 0.2 1.4 1 0 0 1 1 1 1 YEATS family HECT PF00632.25 EAX99028.1 - 3.8e-54 184.2 1.3 6.3e-54 183.5 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 EAX99029.1 - 2.5e-61 204.2 3.7 4.2e-18 65.7 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99029.1 - 1.3e-57 191.5 9.2 8.7e-14 51.7 0.3 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99029.1 - 1.2e-51 172.1 7.6 3.6e-10 39.9 0.0 6.7 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX99029.1 - 1.2e-50 167.8 5.0 1.8e-07 31.3 0.4 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 EAX99029.1 - 3.4e-45 146.8 3.8 5.9e-06 26.2 0.2 8.4 8 0 0 8 8 8 8 Ankyrin repeat Shigella_OspC PF06128.11 EAX99029.1 - 0.011 15.5 0.7 1.6 8.4 0.1 3.4 3 2 2 5 5 5 0 Shigella flexneri OspC protein DUF4988 PF16378.5 EAX99029.1 - 0.032 13.9 0.1 0.42 10.3 0.0 2.5 2 1 0 3 3 3 0 Domain of unknown function Tim44 PF04280.15 EAX99030.1 - 4.7e-16 59.2 0.0 7.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain Pkinase PF00069.25 EAX99031.1 - 6.3e-69 232.3 0.0 7.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99031.1 - 9.8e-32 110.2 0.0 1.3e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX99031.1 - 0.003 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX99031.1 - 0.0033 16.8 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EAX99031.1 - 0.0047 16.6 0.2 0.13 11.9 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX99031.1 - 0.012 15.5 0.0 0.047 13.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX99031.1 - 0.014 14.1 0.0 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Peptidase_C48 PF02902.19 EAX99032.1 - 6.3e-16 58.9 0.2 1.1e-15 58.1 0.2 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Diphthami_syn_2 PF01902.17 EAX99032.1 - 0.014 14.9 0.0 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Diphthamide synthase WD40 PF00400.32 EAX99033.1 - 3.9e-05 24.3 0.4 0.59 11.1 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX99033.1 - 0.0067 16.7 0.0 4.1 7.8 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAX99033.1 - 0.015 15.2 1.0 0.052 13.4 0.3 2.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF4979 PF16351.5 EAX99033.1 - 0.028 14.6 0.4 0.065 13.5 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4979) RAB3GAP2_N PF14655.6 EAX99033.1 - 0.074 12.3 0.3 1.4 8.1 0.1 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus YcxB PF14317.6 EAX99033.1 - 0.11 12.2 6.6 0.1 12.3 0.7 2.7 3 0 0 3 3 3 0 YcxB-like protein Amidase02_C PF12123.8 EAX99034.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX99035.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX99035.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Collagen_bind_2 PF12904.7 EAX99036.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF1325 PF07039.11 EAX99038.1 - 2e-20 73.2 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EAX99038.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Mo25 PF08569.11 EAX99039.1 - 0.0095 15.3 0.6 0.016 14.6 0.6 1.3 1 0 0 1 1 1 1 Mo25-like SFTA2 PF15210.6 EAX99041.1 - 0.078 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Surfactant-associated protein 2 Bac_rhodopsin PF01036.18 EAX99041.1 - 0.23 11.0 6.7 1.9 8.0 1.1 2.2 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein Serpentine_r_xa PF03383.15 EAX99041.1 - 0.67 9.9 8.5 1.8 8.5 0.2 3.2 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7TMR-DISM_7TM PF07695.11 EAX99041.1 - 1.3 8.9 21.4 0.97 9.3 8.1 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling PQ-loop PF04193.14 EAX99042.1 - 1.7e-20 72.6 12.0 4.7e-18 64.7 0.1 3.0 3 1 0 3 3 3 2 PQ loop repeat Amidase02_C PF12123.8 EAX99043.1 - 0.014 15.1 0.1 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX99044.1 - 8.2e-154 510.0 13.4 1e-153 509.7 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99044.1 - 4.1 7.9 6.5 2.6 8.5 0.6 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAX99045.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX99045.1 - 0.088 12.8 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX99046.1 - 0.027 14.9 0.5 0.034 14.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX99046.1 - 1 8.3 2.9 1.1 8.2 2.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX99046.1 - 2 8.4 6.0 2.2 8.3 6.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX99047.1 - 0.02 14.9 0.2 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DDR PF08841.10 EAX99049.1 - 0.08 11.9 0.1 0.083 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3781 PF12636.7 EAX99050.1 - 0.032 14.1 0.8 0.056 13.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) M20_dimer PF07687.14 EAX99051.1 - 5.6e-10 39.1 0.0 2.3e-09 37.1 0.0 2.0 1 1 1 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EAX99051.1 - 1.4e-05 24.9 0.8 0.00013 21.7 0.0 2.5 3 0 0 3 3 3 1 Peptidase family M20/M25/M40 EF-hand_6 PF13405.6 EAX99052.1 - 4.6e-14 51.1 2.1 2.6e-05 23.8 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EAX99052.1 - 6.5e-14 52.1 1.2 4.8e-08 33.4 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX99052.1 - 7.3e-14 50.2 5.0 2.6e-06 26.6 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EAX99052.1 - 8.4e-08 31.4 0.4 8.7e-05 21.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EAX99052.1 - 3.6e-07 29.9 2.8 0.012 15.5 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EAX99052.1 - 7e-06 26.3 0.1 0.11 12.8 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain PSD2 PF07624.11 EAX99052.1 - 0.0034 17.1 0.1 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1585) LRR_5 PF13306.6 EAX99053.1 - 0.00058 19.8 0.1 0.00087 19.3 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 EAX99054.1 - 6.5e-89 294.5 37.3 2.3e-24 85.8 5.4 7.0 2 1 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99054.1 - 1.7e-15 56.5 0.4 0.049 13.4 0.0 8.5 9 1 0 9 9 9 4 Leucine rich repeat rOmpB PF12334.8 EAX99054.1 - 0.0031 17.0 1.5 0.11 12.0 0.0 3.1 3 0 0 3 3 3 1 Rickettsia outer membrane protein B LRR_4 PF12799.7 EAX99054.1 - 1.8 9.1 19.9 7.3 7.2 0.1 6.7 5 3 3 8 8 8 0 Leucine Rich repeats (2 copies) Hydrolase_3 PF08282.12 EAX99056.1 - 0.084 12.6 0.5 1.5 8.5 0.1 2.7 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase DUF3463 PF11946.8 EAX99056.1 - 0.14 11.9 0.9 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) Rep_fac-A_C PF08646.10 EAX99058.1 - 1.7e-25 89.4 0.3 5.5e-25 87.8 0.3 1.9 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EAX99058.1 - 2.8e-21 75.3 0.1 2.9e-16 59.2 0.0 3.0 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 EAX99058.1 - 3.1e-13 49.5 0.1 1.2e-10 41.2 0.1 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EAX99058.1 - 4.4e-10 39.5 0.6 1e-09 38.3 0.6 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Big_10 PF17964.1 EAX99058.1 - 0.04 13.9 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig domain zf-RRN7 PF11781.8 EAX99058.1 - 0.088 12.5 1.3 0.18 11.5 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TFIIA PF03153.13 EAX99058.1 - 0.26 11.2 12.9 0.39 10.7 12.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EAX99058.1 - 3.2 6.3 7.9 4.2 6.0 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4108 PF13390.6 EAX99059.1 - 1.1e-57 194.0 4.2 1.2e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX99060.1 - 1 9.3 6.8 0.071 13.0 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) VIT PF08487.10 EAX99061.1 - 2.5e-20 72.7 0.0 7.7e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EAX99061.1 - 3.5e-20 72.5 0.0 6.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAX99061.1 - 4.6e-15 56.3 0.0 1.2e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAX99061.1 - 1.6e-14 54.4 0.0 4.7e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain CoA_trans PF01144.23 EAX99061.1 - 0.088 12.2 0.0 0.24 10.8 0.1 1.6 2 0 0 2 2 2 0 Coenzyme A transferase DUF4636 PF15468.6 EAX99061.1 - 0.12 12.1 1.9 0.25 11.0 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4636) Tub PF01167.18 EAX99062.1 - 0.0031 17.3 0.2 0.0055 16.5 0.2 1.5 1 1 0 1 1 1 1 Tub family R_equi_Vir PF05526.11 EAX99062.1 - 0.039 13.8 0.3 0.078 12.8 0.3 1.5 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF1053 PF06327.14 EAX99062.1 - 0.099 13.2 2.6 0.23 12.0 2.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) PMT PF02366.18 EAX99063.1 - 7.9e-39 133.7 9.3 7.9e-39 133.7 9.3 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX99063.1 - 9.8e-21 74.3 10.3 9.8e-21 74.3 10.3 3.3 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase CbiD PF01888.17 EAX99065.1 - 0.059 12.7 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 CbiD Cu_amine_oxidN1 PF07833.11 EAX99065.1 - 0.075 13.5 1.0 6.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Copper amine oxidase N-terminal domain GramPos_pilinBB PF16569.5 EAX99065.1 - 0.77 10.6 5.8 3.3 8.5 1.7 2.8 2 1 1 3 3 3 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain GPS2_interact PF15784.5 EAX99066.1 - 0.05 14.0 1.4 0.066 13.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Trypan_PARP PF05887.11 EAX99067.1 - 0.042 13.8 7.8 0.065 13.2 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX99067.1 - 2.6 8.5 4.7 3.7 8.0 4.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Utp14 PF04615.13 EAX99068.1 - 3.5 6.1 25.0 5 5.6 25.0 1.1 1 0 0 1 1 1 0 Utp14 protein PTR PF12789.7 EAX99069.1 - 1.2e-82 271.9 56.2 1.5e-32 111.5 16.0 5.2 2 2 2 4 4 4 3 Phage tail repeat like HS1_rep PF02218.15 EAX99069.1 - 0.002 18.4 0.0 76 3.7 0.0 4.6 5 0 0 5 5 5 0 Repeat in HS1/Cortactin DUF4116 PF13475.6 EAX99069.1 - 0.033 13.9 0.9 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAX99069.1 - 0.38 11.1 8.7 27 5.2 0.2 4.6 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF4404 PF14357.6 EAX99069.1 - 9.1 7.0 10.6 12 6.6 0.3 3.8 2 1 3 5 5 5 0 Domain of unknown function (DUF4404) DUF1493 PF07377.12 EAX99070.1 - 0.031 14.8 1.1 0.04 14.4 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX99070.1 - 0.16 12.0 4.0 3.1 7.9 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAX99071.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99072.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_6 PF13516.6 EAX99073.1 - 0.85 9.8 0.0 0.85 9.8 0.0 3.1 4 0 0 4 4 4 0 Leucine Rich repeat EF-hand_7 PF13499.6 EAX99074.1 - 1.9e-10 41.0 5.2 0.043 14.3 0.2 6.3 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 EAX99074.1 - 6.8e-10 37.8 2.4 0.0045 16.4 0.0 7.1 8 0 0 8 8 8 2 EF hand EF-hand_6 PF13405.6 EAX99074.1 - 1.3e-08 34.1 0.1 1.6 8.9 0.1 7.7 9 0 0 9 9 9 2 EF-hand domain EF-hand_11 PF08976.11 EAX99074.1 - 0.00064 20.6 1.0 2.5 9.0 0.0 4.1 3 2 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 EAX99074.1 - 0.0018 18.1 9.6 0.28 11.1 0.1 5.4 5 1 1 6 6 6 2 EF-hand domain pair DUF1398 PF07166.11 EAX99074.1 - 0.012 15.7 0.5 9.7 6.3 0.0 4.6 7 0 0 7 7 7 0 Protein of unknown function (DUF1398) LRR_5 PF13306.6 EAX99076.1 - 1.7e-94 312.5 70.2 1e-28 99.8 3.0 6.2 3 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99076.1 - 9.4e-21 73.4 17.1 0.0064 16.2 1.4 10.0 6 3 4 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 EAX99076.1 - 0.00035 20.9 12.6 6.5 7.3 0.2 7.6 6 1 0 7 7 7 1 Leucine Rich repeats (2 copies) Ssl1 PF04056.14 EAX99077.1 - 3.9e-29 101.8 0.5 4.7e-29 101.6 0.5 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 EAX99077.1 - 7e-06 26.7 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DegT_DnrJ_EryC1 PF01041.17 EAX99078.1 - 1.5e-51 175.8 0.0 2.6e-50 171.8 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EAX99078.1 - 4.1e-05 23.0 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EAX99078.1 - 0.00082 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAX99078.1 - 0.0015 17.2 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EAX99078.1 - 0.0043 15.8 0.0 0.0061 15.3 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain YL1 PF05764.13 EAX99079.1 - 0.13 12.4 15.9 0.14 12.3 15.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein EIIBC-GUT_N PF03612.14 EAX99079.1 - 0.25 11.1 1.2 0.26 11.0 1.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SDA1 PF05285.12 EAX99079.1 - 0.72 9.2 16.6 0.78 9.1 16.6 1.0 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 EAX99079.1 - 0.81 8.2 15.5 0.85 8.1 15.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 EAX99079.1 - 2 6.9 6.4 1.9 6.9 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EAX99079.1 - 2.1 6.5 11.4 2.2 6.4 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EAX99079.1 - 2.3 7.4 13.3 2.8 7.2 13.3 1.1 1 0 0 1 1 1 0 NOA36 protein Roughex PF06020.11 EAX99079.1 - 6.6 5.7 9.6 7.2 5.6 9.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CNOT11 PF10155.9 EAX99080.1 - 1.8e-08 34.6 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 DUF2183 PF09949.9 EAX99080.1 - 0.05 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Dict-STAT-coil PF09267.10 EAX99080.1 - 0.087 13.2 0.2 0.087 13.2 0.2 2.1 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil KilA-N PF04383.13 EAX99082.1 - 1.3e-14 54.0 0.3 2.4e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 KilA-N domain ESCRT-II PF05871.12 EAX99082.1 - 0.1 12.8 1.1 20 5.4 0.0 2.7 3 1 0 3 3 3 0 ESCRT-II complex subunit NTS PF15447.6 EAX99082.1 - 0.34 11.5 3.5 2.9 8.5 0.9 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 DUF3839 PF12943.7 EAX99083.1 - 3.7e-154 511.2 12.6 4.7e-154 510.8 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX99083.1 - 0.039 14.2 0.5 0.14 12.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 KELK PF15796.5 EAX99083.1 - 2.2 8.8 6.6 1.6 9.2 0.4 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4108 PF13390.6 EAX99085.1 - 5.6e-64 214.4 5.9 6.3e-64 214.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) LRR_8 PF13855.6 EAX99086.1 - 1.6e-06 27.7 3.4 0.03 14.1 0.4 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAX99086.1 - 4.7e-06 26.8 8.7 9.1e-05 22.8 0.8 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAX99086.1 - 0.012 15.1 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 EAX99086.1 - 0.012 16.0 3.9 32 5.6 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4793 PF16041.5 EAX99086.1 - 0.035 14.3 2.0 0.069 13.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) Ada3 PF10198.9 EAX99086.1 - 2.6 8.2 5.3 1.1 9.4 0.5 2.7 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 SUIM_assoc PF16619.5 EAX99088.1 - 0.016 15.3 7.7 0.56 10.3 5.3 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Hormone_3 PF00159.18 EAX99088.1 - 0.022 14.8 0.9 0.083 13.0 0.1 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide Gly-zipper_Omp PF13488.6 EAX99090.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX99090.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX99090.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif YmaF PF12788.7 EAX99092.1 - 0.17 12.4 1.8 5.9 7.5 0.1 2.1 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX99092.1 - 3.6 8.0 8.1 12 6.4 1.8 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAX99093.1 - 4.8e-155 514.1 13.3 6.2e-155 513.7 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAX99093.1 - 0.023 15.1 1.9 0.33 11.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Rx_N PF18052.1 EAX99093.1 - 0.075 13.3 0.2 1.7 9.0 0.0 3.0 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAX99093.1 - 0.081 12.8 0.9 0.29 11.0 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase MitMem_reg PF13012.6 EAX99093.1 - 0.11 12.9 0.4 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX99093.1 - 1.6 9.3 6.3 2.1 8.9 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PA14 PF07691.12 EAX99094.1 - 1.3e-11 44.5 1.2 0.0088 15.9 0.1 4.7 4 1 0 4 4 4 3 PA14 domain EGF_2 PF07974.13 EAX99094.1 - 9.8e-11 41.8 162.3 1e-05 25.8 12.8 10.8 8 3 3 11 11 11 6 EGF-like domain DSL PF01414.19 EAX99094.1 - 1.2e-09 38.3 126.5 4.8e-06 26.8 19.3 7.8 4 2 3 7 7 7 6 Delta serrate ligand GLEYA PF10528.9 EAX99094.1 - 2.8e-06 27.6 2.1 0.015 15.7 0.1 4.8 4 1 0 4 4 4 1 GLEYA domain MHC_I_3 PF16497.5 EAX99094.1 - 0.0017 17.9 0.4 5.7 6.4 0.1 3.6 4 0 0 4 4 4 2 MHC-I family domain FixQ PF05545.11 EAX99094.1 - 0.16 12.0 0.4 0.29 11.1 0.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SLC35F PF06027.12 EAX99095.1 - 9.1e-34 117.3 25.3 1.5e-33 116.6 25.3 1.2 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EAX99095.1 - 4.6e-12 46.3 37.8 1.5e-06 28.4 11.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EAX99095.1 - 0.0013 18.0 15.1 0.0031 16.7 15.1 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter RhoGAP PF00620.27 EAX99096.1 - 1.6e-21 76.7 0.0 3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MOZART1 PF12554.8 EAX99096.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated ThiF PF00899.21 EAX99097.1 - 5.4e-10 39.1 0.0 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 ThiF family E1_4HB PF16191.5 EAX99097.1 - 0.019 15.1 1.0 1 9.6 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin-activating enzyme E1 four-helix bundle DUF4256 PF14066.6 EAX99097.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) PI-PLC-X PF00388.19 EAX99097.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.5 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Autophagy_act_C PF03987.15 EAX99098.1 - 5.1e-12 46.2 0.1 8.6e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ank PF00023.30 EAX99099.1 - 4e-72 235.7 7.9 1.8e-08 34.5 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 EAX99099.1 - 4.5e-70 230.8 6.8 2.7e-11 43.5 0.0 8.0 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99099.1 - 4.8e-65 216.2 9.6 1.9e-14 54.0 0.1 6.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99099.1 - 7.9e-61 201.7 3.6 9.4e-10 38.8 0.0 10.3 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99099.1 - 1.3e-54 175.7 10.7 0.00039 20.6 0.0 12.4 13 0 0 13 13 13 9 Ankyrin repeat DUF3447 PF11929.8 EAX99099.1 - 2.6e-33 113.8 8.6 2.6e-33 113.8 8.6 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAX99099.1 - 0.0069 16.1 0.0 4.4 6.8 0.0 3.7 1 1 0 3 3 3 1 Coiled coil protein 84 PGM_PMM_I PF02878.16 EAX99099.1 - 0.0075 16.0 0.1 15 5.3 0.0 4.5 3 3 3 6 6 6 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Y_phosphatase3 PF13350.6 EAX99099.1 - 0.0076 16.2 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF655 PF04919.12 EAX99099.1 - 0.056 13.4 0.0 25 4.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF655) T4_Gp59_N PF08993.10 EAX99099.1 - 0.5 10.8 7.2 56 4.3 0.0 5.7 5 2 1 7 7 7 0 T4 gene Gp59 loader of gp41 DNA helicase Pkinase PF00069.25 EAX99100.1 - 1.5e-27 96.6 0.0 2.9e-27 95.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99100.1 - 3.1e-13 49.6 0.0 3.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX99100.1 - 0.00011 22.2 0.0 0.0018 18.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX99100.1 - 0.00091 18.1 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX99100.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly-zipper_Omp PF13488.6 EAX99101.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAX99101.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAX99101.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX99101.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif KilA-N PF04383.13 EAX99102.1 - 9.7e-24 83.4 0.2 1.9e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 KilA-N domain Chal_sti_synt_N PF00195.19 EAX99102.1 - 0.31 10.4 0.7 1.2 8.5 0.3 2.0 2 1 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Meiosis_expr PF15163.6 EAX99103.1 - 0.052 14.2 1.3 0.069 13.8 0.5 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAX99103.1 - 0.17 11.6 0.0 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAX99103.1 - 0.45 10.5 8.3 0.18 11.7 2.9 2.6 3 0 0 3 3 3 0 Spo12 family rve PF00665.26 EAX99104.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain DNA_pol_B_2 PF03175.13 EAX99105.1 - 5.6e-29 101.3 9.6 7.2e-29 101.0 9.6 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral C-C_Bond_Lyase PF15617.6 EAX99105.1 - 0.0023 17.2 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold OTCace PF00185.24 EAX99105.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Guanylate_cyc PF00211.20 EAX99106.1 - 7.7e-30 103.9 1.3 2.6e-29 102.1 0.0 2.4 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX99106.1 - 1.2e-12 48.0 2.6 7.1e-12 45.5 2.6 2.5 1 0 0 1 1 1 1 PAS domain T2SSF PF00482.23 EAX99106.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F PAS PF00989.25 EAX99106.1 - 0.0047 16.9 0.3 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAX99106.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain PSP PF04046.16 EAX99107.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99108.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX99109.1 - 0.028 14.9 0.6 0.076 13.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAX99110.1 - 5.1e-156 517.3 12.5 6.5e-156 516.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX99110.1 - 0.044 14.2 2.0 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX99110.1 - 0.48 10.9 6.3 2.5 8.6 0.7 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX99110.1 - 4.7 7.6 7.6 11 6.4 0.1 3.9 3 2 1 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX99111.1 - 4.9e-07 29.5 1.9 4.9e-07 29.5 1.9 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99111.1 - 3.3e-05 24.2 0.2 0.00025 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99111.1 - 4e-05 23.4 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99111.1 - 0.00018 21.5 3.5 0.00045 20.3 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99111.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX99111.1 - 0.0014 18.3 0.4 0.0081 15.8 0.4 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX99111.1 - 0.0017 18.2 0.7 0.0044 16.9 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX99111.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX99111.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX99111.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX99111.1 - 0.093 13.2 0.1 0.74 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2805 PF10985.8 EAX99111.1 - 0.24 11.8 3.2 0.73 10.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) DUF1827 PF08860.10 EAX99111.1 - 0.38 11.0 4.0 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX99113.1 - 5.2e-63 211.3 6.0 5.7e-63 211.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pheromone PF08015.11 EAX99114.1 - 0.033 15.2 1.3 0.35 12.0 0.0 2.6 2 1 0 2 2 2 0 Fungal mating-type pheromone Coilin_N PF15862.5 EAX99114.1 - 1.6 8.5 0.0 1.6 8.5 0.0 5.6 4 2 2 6 6 6 0 Coilin N-terminus E2F_TDP PF02319.20 EAX99115.1 - 4.6e-20 71.4 0.5 6e-11 42.2 0.0 2.4 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EAX99115.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB CLASP_N PF12348.8 EAX99116.1 - 4.1e-15 56.0 0.2 2.6e-14 53.4 0.2 2.1 2 0 0 2 2 2 1 CLASP N terminal ER PF01133.17 EAX99116.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.0 3 0 0 3 3 3 0 Enhancer of rudimentary Gly_rich PF12810.7 EAX99117.1 - 6.2e-39 134.4 30.2 7.1e-39 134.2 30.2 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX99118.1 - 1.2e-26 93.1 23.9 1.5e-15 57.3 8.6 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99118.1 - 1.9e-05 24.3 0.0 0.0046 16.7 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat PI-PLC-X PF00388.19 EAX99118.1 - 0.069 12.7 0.9 5.7 6.5 0.1 3.0 1 1 1 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Gly_rich PF12810.7 EAX99119.1 - 4.9e-39 134.7 35.0 5.9e-39 134.4 35.0 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF4107 PF13389.6 EAX99120.1 - 6.6e-62 208.4 1.9 8.7e-62 208.1 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99120.1 - 0.093 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX99121.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX99122.1 - 7.4e-155 513.5 13.1 9.1e-155 513.2 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) TBCC_N PF16752.5 EAX99122.1 - 0.13 12.7 1.7 2.2 8.7 0.3 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain KELK PF15796.5 EAX99122.1 - 4.6 7.8 7.5 2.6 8.6 1.0 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4106 PF13388.6 EAX99123.1 - 2.1e-167 557.7 22.0 3.2e-167 557.0 22.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAX99123.1 - 0.011 16.0 0.0 0.7 10.2 0.1 2.5 2 0 0 2 2 2 0 Kidney androgen-regulated WYL_3 PF18488.1 EAX99123.1 - 0.56 10.6 6.9 6.5 7.2 0.4 3.2 3 0 0 3 3 3 0 WYL domain DUF2897 PF11446.8 EAX99124.1 - 1.7 8.6 3.7 3.7 7.5 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX99125.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX99125.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX99125.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX99125.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAX99125.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAX99125.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAX99125.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAX99126.1 - 1.7e-155 515.6 12.0 2.1e-155 515.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PRD PF00874.20 EAX99126.1 - 0.44 10.9 4.0 1 9.7 0.1 3.1 2 2 2 4 4 4 0 PRD domain KELK PF15796.5 EAX99126.1 - 6.5 7.3 6.9 4.8 7.7 0.5 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX99127.1 - 4.1e-74 244.5 53.8 3.8e-30 103.7 13.8 5.1 2 2 2 4 4 4 3 Phage tail repeat like HS1_rep PF02218.15 EAX99127.1 - 0.024 15.0 0.0 89 3.5 0.0 3.5 3 0 0 3 3 3 0 Repeat in HS1/Cortactin DUF4116 PF13475.6 EAX99127.1 - 0.037 13.7 0.9 0.069 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) SAS4 PF15460.6 EAX99127.1 - 0.66 10.1 12.2 18 5.5 0.1 4.1 2 1 3 5 5 5 0 Something about silencing, SAS, complex subunit 4 PH_TFIIH PF08567.11 EAX99127.1 - 0.73 10.2 10.5 11 6.4 0.3 4.8 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF1493 PF07377.12 EAX99128.1 - 0.078 13.4 0.5 0.2 12.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAX99130.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ATG16 PF08614.11 EAX99131.1 - 4.1e-16 59.8 97.9 1.1e-05 25.8 24.3 5.9 1 1 5 6 6 6 6 Autophagy protein 16 (ATG16) IFT57 PF10498.9 EAX99131.1 - 1.7e-07 30.5 107.1 0.019 14.0 11.9 6.7 1 1 7 8 8 8 7 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.9 EAX99131.1 - 3.1e-07 30.5 124.5 0.22 11.6 26.5 7.7 1 1 6 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 EAX99131.1 - 5.6e-06 26.3 100.0 0.0028 17.5 18.4 6.5 1 1 6 7 7 7 5 Protein of unknown function (DUF724) UPF0242 PF06785.11 EAX99131.1 - 6.2e-06 26.5 125.8 0.0013 18.9 29.3 6.0 1 1 5 6 6 6 3 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 EAX99131.1 - 4.3e-05 23.4 122.6 0.17 11.7 9.1 5.3 2 1 3 5 5 5 4 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 EAX99131.1 - 0.012 15.1 120.7 0.067 12.7 16.5 6.7 1 1 3 5 5 5 0 Leucine zipper Vps4_C PF09336.10 EAX99131.1 - 0.013 15.5 2.8 0.032 14.2 0.1 3.0 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Spc7 PF08317.11 EAX99131.1 - 0.017 14.0 113.3 0.16 10.8 25.3 4.8 1 1 5 6 6 6 0 Spc7 kinetochore protein APG6_N PF17675.1 EAX99131.1 - 0.14 12.6 118.2 0.22 12.0 23.5 6.1 1 1 5 6 6 6 0 Apg6 coiled-coil region Fez1 PF06818.15 EAX99131.1 - 0.55 10.7 101.8 0.63 10.5 20.5 4.9 1 1 4 5 5 5 0 Fez1 Lebercilin PF15619.6 EAX99131.1 - 1.6 8.3 121.9 0.72 9.5 19.8 6.5 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EAX99131.1 - 1.9 7.8 131.2 1.3 8.3 28.4 6.3 1 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EAX99131.1 - 3 7.9 115.5 1.2 9.2 15.1 7.5 2 1 8 11 11 11 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 EAX99131.1 - 7.1 6.1 73.3 0.3 10.6 9.2 6.9 2 2 3 6 6 6 0 PspA/IM30 family Phage_GP20 PF06810.11 EAX99131.1 - 9.3 6.0 121.8 1.2 8.9 6.5 8.5 1 1 5 7 7 7 0 Phage minor structural protein GP20 Ank_4 PF13637.6 EAX99132.1 - 1.3e-09 38.4 0.2 3.3e-05 24.3 0.0 3.5 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99132.1 - 2.8e-05 24.2 1.3 0.37 11.5 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EAX99132.1 - 0.0001 22.8 0.0 0.033 14.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99132.1 - 0.00057 20.1 0.1 0.19 12.1 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99132.1 - 0.048 14.1 0.0 6.6 7.4 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat DUF1091 PF06477.13 EAX99133.1 - 0.0068 16.9 1.3 0.0068 16.9 1.3 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1091) Nab2 PF11517.8 EAX99133.1 - 0.77 10.1 3.8 8.5 6.7 0.1 3.5 3 1 0 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Ank_2 PF12796.7 EAX99134.1 - 0.00046 20.7 0.0 0.043 14.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99134.1 - 0.0057 17.1 0.0 3 8.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EAX99134.1 - 0.02 15.5 0.0 3.8 8.2 0.0 3.8 4 1 0 4 4 4 0 Ankyrin repeats (many copies) GldM_N PF12081.8 EAX99134.1 - 0.067 13.3 0.5 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 GldM N-terminal domain DUF3447 PF11929.8 EAX99134.1 - 7.4 6.6 15.7 0.053 13.5 3.8 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) Calreticulin PF00262.18 EAX99135.1 - 3.2e-53 180.9 13.5 5.4e-40 137.4 4.6 2.1 1 1 1 2 2 2 2 Calreticulin family RRM_1 PF00076.22 EAX99136.1 - 6.2e-16 58.0 0.0 1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TENA_THI-4 PF03070.16 EAX99137.1 - 0.0074 16.1 0.4 0.026 14.4 0.1 1.8 2 0 0 2 2 2 1 TENA/THI-4/PQQC family DUF3863 PF12979.7 EAX99137.1 - 0.034 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) DUF1664 PF07889.12 EAX99137.1 - 0.034 14.2 1.5 0.067 13.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 EAX99137.1 - 3.1 7.7 7.3 0.12 12.3 0.5 2.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain AAA PF00004.29 EAX99138.1 - 1.2e-43 148.7 0.0 2.4e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAX99138.1 - 7.6e-14 51.3 0.1 1.8e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EAX99138.1 - 1.8e-08 34.2 0.3 4.5e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EAX99138.1 - 2.7e-07 30.7 0.0 1.9e-06 28.0 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAX99138.1 - 1e-06 29.2 0.0 0.00051 20.5 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EAX99138.1 - 5.7e-05 22.9 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAX99138.1 - 7.8e-05 23.0 1.6 0.038 14.3 0.0 2.7 2 1 1 3 3 2 2 AAA domain ATPase PF06745.13 EAX99138.1 - 0.00012 21.5 1.0 0.09 12.1 0.0 3.0 2 1 1 3 3 3 1 KaiC AAA_2 PF07724.14 EAX99138.1 - 0.00016 21.8 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EAX99138.1 - 0.00036 21.1 0.0 0.0023 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAX99138.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAX99138.1 - 0.0093 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 EAX99138.1 - 0.011 15.4 0.9 0.02 14.5 0.2 1.7 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 EAX99138.1 - 0.012 14.8 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EAX99138.1 - 0.014 15.7 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 EAX99138.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAX99138.1 - 0.021 14.2 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAX99138.1 - 0.022 14.4 0.1 0.11 12.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EAX99138.1 - 0.025 14.1 0.1 0.13 11.8 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EAX99138.1 - 0.032 13.8 0.2 0.21 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAX99138.1 - 0.042 13.6 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAX99138.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX99138.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EAX99138.1 - 0.074 12.1 0.1 0.074 12.1 0.1 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EAX99138.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 EAX99138.1 - 0.12 12.2 4.2 0.33 10.8 1.7 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 EAX99138.1 - 0.12 11.6 2.6 0.23 10.8 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_3 PF07726.11 EAX99138.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EAX99138.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Rpp20 PF12328.8 EAX99138.1 - 0.29 11.1 1.6 0.52 10.3 1.6 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Tub PF01167.18 EAX99139.1 - 2e-08 34.3 0.3 5.2e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 Tub family PhetRS_B1 PF18262.1 EAX99139.1 - 0.12 12.6 0.5 0.32 11.3 0.5 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain RRM_1 PF00076.22 EAX99140.1 - 0.0042 16.9 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 EAX99141.1 - 2.6e-80 265.1 51.6 1.6e-15 57.4 0.8 6.5 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99141.1 - 3.3e-73 239.1 20.0 5e-08 33.0 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 EAX99141.1 - 5.1e-66 218.3 23.0 3.2e-11 43.5 0.2 10.7 2 1 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99141.1 - 5.2e-57 183.1 20.3 3.6e-06 26.9 0.1 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 EAX99141.1 - 9.3e-43 143.7 29.4 5.9e-09 36.0 0.2 6.3 4 2 4 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99141.1 - 1.3e-37 127.6 14.5 1.4e-37 127.5 9.6 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Env-gp36 PF09590.10 EAX99141.1 - 0.003 16.1 1.2 0.22 9.9 0.1 2.7 1 1 2 3 3 3 1 Lentivirus surface glycoprotein DUF5639 PF18690.1 EAX99141.1 - 0.0066 16.6 0.5 50 4.1 0.2 3.9 3 1 0 3 3 3 0 Family of unknown function (DUF5639) RL PF17797.1 EAX99141.1 - 0.009 15.9 8.1 10 6.1 0.0 5.1 5 1 1 6 6 6 1 RL domain Herpes_UL31 PF02718.14 EAX99141.1 - 0.014 14.4 1.1 0.023 13.7 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL31-like protein RNase_PH_C PF03725.15 EAX99141.1 - 0.065 13.3 0.2 20 5.3 0.0 4.1 4 0 0 4 4 4 0 3' exoribonuclease family, domain 2 DUF503 PF04456.12 EAX99141.1 - 0.074 12.9 0.1 18 5.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF503) PH_8 PF15409.6 EAX99141.1 - 0.098 13.0 10.5 8.9 6.7 0.0 5.6 2 1 5 7 7 7 0 Pleckstrin homology domain BCS1_N PF08740.11 EAX99141.1 - 0.098 12.6 1.6 6.3 6.7 0.0 3.7 4 1 0 4 4 4 0 BCS1 N terminal Peptidase_M18 PF02127.15 EAX99142.1 - 6e-71 239.5 0.0 2.7e-70 237.3 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAX99142.1 - 9.7e-05 21.5 0.0 0.00079 18.5 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase TRAP-gamma PF07074.12 EAX99143.1 - 7.3e-08 32.2 6.4 3e-05 23.6 2.5 2.0 1 1 1 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2070 PF09843.9 EAX99143.1 - 0.0071 14.7 4.4 0.0082 14.5 4.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) FtsX PF02687.21 EAX99143.1 - 0.51 10.8 8.4 4.1 7.9 5.3 2.7 2 1 0 2 2 2 0 FtsX-like permease family Sel1 PF08238.12 EAX99144.1 - 9.4e-07 29.3 5.3 0.022 15.4 0.3 3.1 3 0 0 3 3 3 2 Sel1 repeat Methyltr_RsmB-F PF01189.17 EAX99145.1 - 9.8e-67 224.5 0.0 1.6e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EAX99145.1 - 1e-09 38.7 0.0 3.5e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EAX99145.1 - 9.4e-05 22.6 0.1 0.00018 21.7 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EAX99145.1 - 0.00036 20.4 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EAX99145.1 - 0.0028 18.3 0.0 0.0064 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EAX99145.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 EAX99145.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EAX99145.1 - 0.06 12.9 0.2 0.13 11.8 0.2 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 EAX99145.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family KH_8 PF17903.1 EAX99146.1 - 7e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EAX99146.1 - 0.00035 20.3 0.7 0.00065 19.5 0.7 1.4 1 0 0 1 1 1 1 KH domain Ank_2 PF12796.7 EAX99147.1 - 8.3e-31 106.4 0.0 2.4e-20 72.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99147.1 - 8.2e-23 79.8 0.0 1.1e-05 25.6 0.0 4.8 5 0 0 5 5 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX99147.1 - 3.8e-22 78.4 0.0 1.4e-06 28.7 0.0 3.6 4 0 0 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99147.1 - 1.4e-21 76.3 0.0 6e-07 29.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99147.1 - 5.7e-20 69.3 0.0 0.0027 18.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat ATG16 PF08614.11 EAX99147.1 - 0.0013 19.0 10.0 0.002 18.4 10.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EAX99147.1 - 0.0015 19.1 17.3 0.0021 18.6 16.9 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF3843 PF12954.7 EAX99147.1 - 0.0023 17.0 1.5 0.0028 16.7 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3843) ABC_tran_CTD PF16326.5 EAX99147.1 - 0.0029 17.8 9.1 0.0062 16.8 9.1 1.5 1 0 0 1 1 1 1 ABC transporter C-terminal domain Spc7 PF08317.11 EAX99147.1 - 0.0036 16.2 9.1 0.005 15.8 9.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Wtap PF17098.5 EAX99147.1 - 0.0038 17.2 7.5 0.0068 16.3 7.5 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family Het-C PF07217.11 EAX99147.1 - 0.0043 15.7 3.6 0.0053 15.4 3.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FapA PF03961.13 EAX99147.1 - 0.0053 15.4 10.5 0.0053 15.4 10.5 1.7 2 0 0 2 2 2 1 Flagellar Assembly Protein A FH2 PF02181.23 EAX99147.1 - 0.006 15.7 7.0 0.0091 15.2 7.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Spc29 PF17082.5 EAX99147.1 - 0.0068 16.3 6.7 0.0097 15.8 6.7 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF812 PF05667.11 EAX99147.1 - 0.013 14.5 10.7 0.017 14.0 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) OmpH PF03938.14 EAX99147.1 - 0.016 15.5 10.7 0.026 14.8 10.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 EAX99147.1 - 0.017 15.1 6.8 0.031 14.3 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GBP_C PF02841.14 EAX99147.1 - 0.018 14.5 9.8 0.027 13.9 9.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FliJ PF02050.16 EAX99147.1 - 0.023 14.9 7.7 0.044 14.0 7.7 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein LMBR1 PF04791.16 EAX99147.1 - 0.026 13.4 5.9 0.032 13.2 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ACCA PF03255.14 EAX99147.1 - 0.028 14.3 3.3 0.046 13.6 3.3 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2408 PF10303.9 EAX99147.1 - 0.037 14.6 8.3 0.071 13.7 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4407 PF14362.6 EAX99147.1 - 0.038 13.3 3.4 0.057 12.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 EAX99147.1 - 0.054 13.7 5.0 0.14 12.4 5.0 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG AAA_32 PF13654.6 EAX99147.1 - 0.059 12.1 6.4 0.079 11.7 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF262 PF03235.14 EAX99147.1 - 0.073 13.2 9.3 0.11 12.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Phage_GPO PF05929.11 EAX99147.1 - 0.098 12.3 3.3 0.14 11.7 3.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YlqD PF11068.8 EAX99147.1 - 0.099 13.0 10.7 0.17 12.2 10.7 1.4 1 0 0 1 1 1 0 YlqD protein DUF2203 PF09969.9 EAX99147.1 - 0.11 13.3 6.0 0.22 12.3 6.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF745 PF05335.13 EAX99147.1 - 0.12 12.1 3.8 0.19 11.4 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 EAX99147.1 - 0.13 10.1 6.9 0.17 9.8 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 EAX99147.1 - 0.15 12.1 8.8 0.054 13.6 2.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 EAX99147.1 - 0.16 12.5 6.3 0.32 11.6 6.3 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.13 EAX99147.1 - 0.19 10.9 8.2 0.29 10.4 8.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein zf-CpG_bind_C PF12269.8 EAX99147.1 - 0.24 11.2 6.1 0.35 10.6 6.1 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF3450 PF11932.8 EAX99147.1 - 0.28 10.4 10.5 0.45 9.8 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Occludin_ELL PF07303.13 EAX99147.1 - 0.33 11.7 9.4 0.54 11.0 3.5 2.6 1 1 1 2 2 2 0 Occludin homology domain NikR_C PF08753.11 EAX99147.1 - 0.33 11.1 1.7 22 5.3 0.0 2.8 2 1 1 3 3 2 0 NikR C terminal nickel binding domain NPV_P10 PF05531.12 EAX99147.1 - 0.34 11.4 12.0 6.3 7.3 11.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EAX99147.1 - 0.35 10.4 4.8 0.44 10.1 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EAX99147.1 - 0.38 11.0 13.6 0.76 10.0 10.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin PF02996.17 EAX99147.1 - 0.39 10.6 14.6 0.12 12.2 4.9 2.7 1 1 1 2 2 2 0 Prefoldin subunit PCRF PF03462.18 EAX99147.1 - 0.4 10.5 7.2 0.6 9.9 7.2 1.3 1 0 0 1 1 1 0 PCRF domain Allexi_40kDa PF05549.11 EAX99147.1 - 0.41 10.1 5.7 0.59 9.6 5.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Muted PF14942.6 EAX99147.1 - 0.53 10.6 16.8 0.74 10.1 15.9 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Swi5 PF07061.11 EAX99147.1 - 0.62 10.2 17.2 0.3 11.2 8.2 2.5 1 1 1 2 2 2 0 Swi5 Tho2 PF11262.8 EAX99147.1 - 0.7 9.0 9.7 1.1 8.5 9.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spc24 PF08286.11 EAX99147.1 - 0.74 10.1 18.5 2.3 8.5 12.4 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 60KD_IMP PF02096.20 EAX99147.1 - 0.75 9.7 4.5 1.5 8.7 4.5 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein DUF948 PF06103.11 EAX99147.1 - 0.83 9.9 7.2 4 7.7 5.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 EAX99147.1 - 0.83 10.0 6.3 2.4 8.5 0.2 2.5 1 1 1 2 2 2 0 Rx N-terminal domain PDDEXK_6 PF04720.12 EAX99147.1 - 0.85 9.5 5.8 1.3 8.9 5.8 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function MCU PF04678.13 EAX99147.1 - 0.92 9.6 4.0 1.7 8.7 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter GTP-bdg_M PF16360.5 EAX99147.1 - 1 10.0 7.0 11 6.7 0.7 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF1640 PF07798.11 EAX99147.1 - 1.1 9.3 13.5 2.1 8.4 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) BLOC1_2 PF10046.9 EAX99147.1 - 1.3 9.4 14.6 2 8.8 12.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bud13 PF09736.9 EAX99147.1 - 1.8 8.9 8.9 3.1 8.2 8.9 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Csm1_N PF18504.1 EAX99147.1 - 1.9 8.9 14.1 4.3 7.7 6.5 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain PIN_8 PF18476.1 EAX99147.1 - 2 8.2 13.6 4.3 7.1 13.6 1.5 1 1 0 1 1 1 0 PIN like domain DUF2400 PF09674.10 EAX99147.1 - 2 8.3 5.3 3.9 7.4 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) DUF349 PF03993.12 EAX99147.1 - 2.2 8.7 8.0 7 7.0 2.8 2.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF4175 PF13779.6 EAX99147.1 - 2.2 6.1 7.9 2.8 5.7 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4200 PF13863.6 EAX99147.1 - 2.5 8.5 16.6 29 5.1 16.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 EAX99147.1 - 2.8 7.7 13.7 0.76 9.6 9.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) LPP PF04728.13 EAX99147.1 - 3 8.3 9.8 1.5e+02 2.9 9.7 3.0 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF1090 PF06476.12 EAX99147.1 - 3.3 7.9 13.6 1.9 8.6 9.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) GrpE PF01025.19 EAX99147.1 - 3.9 7.1 14.6 12 5.5 14.6 1.8 1 1 0 1 1 1 0 GrpE CCDC-167 PF15188.6 EAX99147.1 - 4.7 7.6 14.4 2.7 8.4 12.0 1.8 1 1 1 2 2 1 0 Coiled-coil domain-containing protein 167 PAP_central PF04928.17 EAX99147.1 - 7.7 5.4 7.3 12 4.8 7.3 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain ZapB PF06005.12 EAX99147.1 - 8.3 6.9 19.2 1.1e+02 3.4 19.2 2.3 1 1 0 1 1 1 0 Cell division protein ZapB TraF_2 PF13729.6 EAX99147.1 - 8.9 5.6 8.3 1.8 7.8 3.9 1.9 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein FemAB PF02388.16 EAX99147.1 - 8.9 5.1 10.3 14 4.4 10.3 1.3 1 0 0 1 1 1 0 FemAB family SopA PF13981.6 EAX99148.1 - 0.37 11.2 5.3 0.28 11.6 0.3 3.4 4 0 0 4 4 4 0 SopA-like central domain hEGF PF12661.7 EAX99149.1 - 0.051 14.2 11.9 0.39 11.4 3.1 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.7 EAX99149.1 - 0.14 12.1 10.4 0.37 10.7 0.9 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_3 PF12947.7 EAX99149.1 - 0.15 12.3 17.6 0.51 10.6 11.3 2.7 2 0 0 2 2 2 0 EGF domain EGF PF00008.27 EAX99149.1 - 1 9.7 15.6 3.3 8.1 7.3 2.5 2 0 0 2 2 2 0 EGF-like domain Zip PF02535.22 EAX99149.1 - 7.1 5.7 7.7 12 5.1 7.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EAX99149.1 - 8.4 5.0 11.7 12 4.5 11.7 1.2 1 0 0 1 1 1 0 Presenilin Bd3614_N PF14442.6 EAX99150.1 - 0.22 11.8 0.0 40 4.6 0.0 3.0 1 1 1 3 3 3 0 Bd3614-like deaminase N-terminal TPR_MLP1_2 PF07926.12 EAX99151.1 - 0.00028 21.0 1.5 0.00028 21.0 1.5 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4800 PF16057.5 EAX99151.1 - 0.0075 15.6 2.9 0.0075 15.6 2.9 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4800) Syntaxin-6_N PF09177.11 EAX99151.1 - 0.032 14.8 3.2 0.032 14.8 3.2 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2459 PF09601.10 EAX99151.1 - 0.039 13.7 0.4 0.071 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) IL5 PF02025.15 EAX99151.1 - 0.045 14.0 0.2 0.045 14.0 0.2 2.3 2 1 1 3 3 3 0 Interleukin 5 ACR_tran PF00873.19 EAX99151.1 - 0.06 11.0 0.5 0.079 10.6 0.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FAD_SOX PF18371.1 EAX99151.1 - 0.11 12.9 4.5 8.5 6.8 0.1 3.4 1 1 2 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF489 PF04356.12 EAX99151.1 - 0.12 12.4 4.6 0.097 12.7 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Swi5 PF07061.11 EAX99151.1 - 0.15 12.2 12.8 0.26 11.4 4.3 3.4 3 1 0 3 3 3 0 Swi5 DUF1664 PF07889.12 EAX99151.1 - 0.22 11.6 2.3 0.4 10.7 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GxGYxYP_C PF14323.6 EAX99151.1 - 0.64 9.8 2.4 5.5 6.8 0.9 2.0 1 1 1 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain NRBF2 PF08961.10 EAX99151.1 - 0.78 9.3 9.4 10 5.7 0.1 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 EAX99151.1 - 1.5 9.1 12.6 0.29 11.4 3.2 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 EAX99151.1 - 5.9 6.1 8.7 7 5.9 8.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M75 PF09375.10 EAX99152.1 - 0.21 11.0 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Imelysin Ank_2 PF12796.7 EAX99153.1 - 1.5e-213 692.1 26.5 7.1e-16 58.6 0.0 14.7 1 1 15 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99153.1 - 5.9e-170 545.1 9.9 1.5e-05 25.2 0.0 26.2 26 0 0 26 26 26 26 Ankyrin repeat Ank_4 PF13637.6 EAX99153.1 - 1e-162 526.6 0.0 2.3e-11 44.0 0.0 18.1 9 7 12 22 22 22 22 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99153.1 - 8.5e-148 478.5 16.4 5.4e-11 42.5 0.0 24.6 2 1 24 26 26 26 26 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99153.1 - 5.1e-138 432.0 0.0 0.00025 21.2 0.0 26.3 26 0 0 26 26 26 26 Ankyrin repeat L_protein_N PF15518.6 EAX99153.1 - 2.7e-14 52.8 0.0 7.9 6.4 0.0 13.5 5 3 11 16 16 16 1 L protein N-terminus DUF3083 PF11281.8 EAX99153.1 - 2.7e-08 33.5 6.6 1.1 8.5 0.0 8.7 3 2 4 9 9 9 3 Protein of unknown function (DUF3083) DUF1897 PF09005.10 EAX99153.1 - 4.7e-05 22.8 6.1 1.4e+02 2.1 0.0 12.4 20 0 0 20 20 20 0 Domain of unknown function (DUF1897) FAD_binding_6 PF00970.24 EAX99153.1 - 0.0038 17.5 0.9 26 5.2 0.0 5.6 7 1 1 8 8 8 0 Oxidoreductase FAD-binding domain Ribosomal_L17 PF01196.19 EAX99153.1 - 0.018 15.9 0.0 22 6.0 0.0 4.9 3 3 1 4 4 4 0 Ribosomal protein L17 DUF4107 PF13389.6 EAX99154.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99154.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Gly_rich PF12810.7 EAX99157.1 - 4.2e-40 138.2 57.8 5.2e-40 137.9 57.8 1.1 1 0 0 1 1 1 1 Glycine rich protein HSP70 PF00012.20 EAX99158.1 - 1.6e-08 33.3 0.0 3.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Hsp70 protein STPPase_N PF16891.5 EAX99158.1 - 0.21 12.1 1.6 0.9 10.0 0.0 2.7 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain bZIP_1 PF00170.21 EAX99159.1 - 7.1e-06 26.0 6.8 3.5e-05 23.8 7.1 1.9 1 1 1 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 EAX99159.1 - 0.005 17.1 0.3 0.0091 16.3 0.3 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_2 PF07716.15 EAX99159.1 - 0.0051 16.9 5.1 0.0051 16.9 5.1 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EAX99159.1 - 0.072 13.6 4.5 0.11 13.1 4.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor SAVED PF18145.1 EAX99159.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Prominin PF05478.11 EAX99159.1 - 0.12 10.4 2.7 0.14 10.1 2.7 1.0 1 0 0 1 1 1 0 Prominin DUF2205 PF10224.9 EAX99159.1 - 2.4 8.2 7.1 8.2 6.5 7.1 1.9 1 1 0 1 1 1 0 Short coiled-coil protein Frag1 PF10277.9 EAX99160.1 - 2.1e-05 24.2 3.9 2.7e-05 23.8 3.9 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2232 PF09991.9 EAX99160.1 - 0.25 10.5 13.1 0.081 12.1 10.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Polysacc_synt_C PF14667.6 EAX99160.1 - 0.6 10.2 7.9 4.8 7.2 1.3 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF4107 PF13389.6 EAX99162.1 - 2.4e-66 222.9 13.0 1.1e-64 217.4 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99162.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAX99163.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAX99165.1 - 5e-157 520.6 13.7 6.4e-157 520.2 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX99165.1 - 0.067 13.6 0.4 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAX99165.1 - 0.14 12.0 0.7 0.4 10.5 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX99165.1 - 0.65 10.5 4.6 4.9 7.7 0.3 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX99167.1 - 3.6e-41 139.5 0.7 7.3e-41 138.5 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DNA_pol_B_2 PF03175.13 EAX99168.1 - 2.3e-10 39.9 2.6 1.7e-09 37.0 2.1 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAX99168.1 - 0.051 12.3 1.9 3.2 6.3 1.4 3.1 2 1 0 2 2 2 0 DNA polymerase family B gpUL132 PF11359.8 EAX99168.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 PapD_N PF00345.20 EAX99169.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAX99170.1 - 0.026 14.9 1.1 0.031 14.7 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAX99170.1 - 1.7 7.6 4.7 1.8 7.5 4.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAX99170.1 - 5.7 6.9 8.0 6.9 6.7 8.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX99171.1 - 0.005 16.8 0.4 0.0066 16.4 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX99172.1 - 0.029 14.3 7.2 0.046 13.7 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gal11_ABD1 PF18535.1 EAX99176.1 - 0.059 13.5 0.4 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) FliJ PF02050.16 EAX99178.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX99179.1 - 8.1e-38 130.1 1.7 9.6e-38 129.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99179.1 - 0.069 13.5 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3417 PF11897.8 EAX99180.1 - 0.089 13.2 0.5 0.11 13.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2897 PF11446.8 EAX99180.1 - 0.82 9.6 3.5 1.7 8.6 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX99181.1 - 1.9e-53 180.2 7.8 2.1e-53 180.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) SKG6 PF08693.10 EAX99182.1 - 8.2e-06 25.1 0.1 1.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 EAX99182.1 - 0.00036 21.0 0.1 0.00062 20.2 0.1 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4448 PF14610.6 EAX99182.1 - 0.001 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EVI2A PF05399.11 EAX99182.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF3377 PF11857.8 EAX99182.1 - 0.0033 17.3 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 EAX99182.1 - 0.0051 16.7 0.1 0.0094 15.9 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family PQQ PF01011.21 EAX99183.1 - 0.085 12.8 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 PQQ enzyme repeat mRNA_cap_enzyme PF01331.19 EAX99184.1 - 3.6e-05 23.7 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Ank_2 PF12796.7 EAX99185.1 - 1.2e-107 352.7 79.9 1e-16 61.2 2.2 8.0 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99185.1 - 1.9e-92 302.5 35.1 7.7e-14 51.9 0.2 14.1 4 2 11 15 15 15 11 Ankyrin repeats (many copies) Ank PF00023.30 EAX99185.1 - 3.8e-91 295.9 26.1 9.9e-08 32.1 0.0 12.4 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAX99185.1 - 1.3e-68 226.2 36.4 3.7e-11 43.0 0.1 8.9 6 3 5 11 11 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99185.1 - 5.1e-67 213.8 29.3 3.7e-05 23.8 0.1 13.7 14 0 0 14 14 13 10 Ankyrin repeat DUF3447 PF11929.8 EAX99185.1 - 2.3e-35 120.4 8.5 2.3e-35 120.4 8.5 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAX99185.1 - 0.0059 16.7 35.0 4 7.7 0.4 9.9 10 1 1 11 11 11 2 Protein of unknown function (DUF3718) BtrH_N PF14399.6 EAX99185.1 - 0.012 15.8 0.0 19 5.5 0.0 3.5 3 1 0 3 3 3 0 Butirosin biosynthesis protein H, N-terminal PrmC_N PF17827.1 EAX99185.1 - 0.1 13.2 7.8 1.5e+02 3.0 0.1 6.6 5 3 2 7 7 7 0 PrmC N-terminal domain CCDC84 PF14968.6 EAX99185.1 - 0.15 11.7 20.4 3.8 7.0 0.3 4.4 1 1 1 2 2 2 0 Coiled coil protein 84 DUF2149 PF09919.9 EAX99185.1 - 0.25 11.6 1.9 1.5e+02 2.7 0.0 4.8 3 2 3 7 7 7 0 Uncharacterized conserved protein (DUF2149) Topo_Zn_Ribbon PF08272.11 EAX99185.1 - 3.5 7.4 10.4 51 3.6 0.0 6.0 8 0 0 8 8 8 0 Topoisomerase I zinc-ribbon-like DUF563 PF04577.14 EAX99186.1 - 2.6e-32 112.6 0.9 4e-32 112.0 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) UCH PF00443.29 EAX99187.1 - 5.8e-15 55.5 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAX99187.1 - 1.6e-11 44.7 0.1 3.7e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EAX99187.1 - 7.2e-06 25.8 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn_Tnp_IS1595 PF12760.7 EAX99187.1 - 0.15 12.1 0.2 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 EAX99187.1 - 0.15 12.0 0.6 2.6 8.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain LUC7 PF03194.15 EAX99188.1 - 0.0014 18.3 0.9 0.0014 18.3 0.9 3.9 3 1 0 4 4 4 1 LUC7 N_terminus ApoLp-III PF07464.11 EAX99188.1 - 0.0016 18.6 23.1 0.2 11.8 1.5 4.4 4 0 0 4 4 4 3 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 EAX99188.1 - 0.0042 17.1 22.0 0.043 13.9 1.3 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) HrpB7 PF09486.10 EAX99188.1 - 0.0068 16.8 2.4 0.0068 16.8 2.4 3.1 3 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) LPP PF04728.13 EAX99188.1 - 0.012 15.9 15.6 0.24 11.8 5.1 4.6 4 1 0 4 4 3 0 Lipoprotein leucine-zipper DUF3340 PF11818.8 EAX99188.1 - 0.018 15.2 1.8 0.018 15.2 1.8 3.8 3 2 1 4 4 3 0 C-terminal domain of tail specific protease (DUF3340) DUF948 PF06103.11 EAX99188.1 - 0.059 13.6 16.9 3.2 8.1 1.5 5.1 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Cnd1 PF12717.7 EAX99188.1 - 0.073 13.1 0.2 0.073 13.1 0.2 2.9 3 1 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 SNARE PF05739.19 EAX99188.1 - 0.086 12.8 0.6 0.19 11.8 0.6 1.6 1 0 0 1 1 1 0 SNARE domain TMPIT PF07851.13 EAX99188.1 - 0.088 12.0 31.9 0.82 8.8 12.6 3.6 3 1 0 3 3 3 0 TMPIT-like protein MAD PF05557.13 EAX99188.1 - 0.09 11.1 37.0 0.055 11.8 4.8 3.0 3 0 0 3 3 3 0 Mitotic checkpoint protein NPV_P10 PF05531.12 EAX99188.1 - 0.091 13.2 18.9 3.9 8.0 1.9 5.1 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EAX99188.1 - 0.16 10.8 37.7 0.081 11.8 7.3 4.0 3 1 0 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 EAX99188.1 - 0.25 11.8 29.7 0.074 13.5 9.9 3.1 2 1 0 2 2 2 0 Fez1 Uds1 PF15456.6 EAX99188.1 - 0.35 11.0 24.4 0.11 12.6 7.4 3.7 2 2 0 2 2 2 0 Up-regulated During Septation WXG100 PF06013.12 EAX99188.1 - 0.36 11.1 12.3 0.25 11.6 2.7 4.4 4 1 1 5 5 5 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 EAX99188.1 - 0.38 10.9 32.7 0.097 12.8 5.6 4.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Flagellin_N PF00669.20 EAX99188.1 - 0.46 10.6 15.3 0.41 10.8 0.3 3.4 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF4041 PF13250.6 EAX99188.1 - 0.54 10.2 8.3 6.1 6.8 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) BicD PF09730.9 EAX99188.1 - 0.87 7.9 35.1 0.033 12.6 19.5 3.0 1 1 1 3 3 3 0 Microtubule-associated protein Bicaudal-D COG5 PF10392.9 EAX99188.1 - 1.2 9.3 21.6 0.13 12.5 3.4 3.8 3 1 1 4 4 4 0 Golgi transport complex subunit 5 DUF4239 PF14023.6 EAX99188.1 - 1.3 8.7 5.6 0.96 9.1 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) Fzo_mitofusin PF04799.13 EAX99188.1 - 1.4 8.5 22.8 0.26 10.8 1.5 4.3 3 1 1 4 4 4 0 fzo-like conserved region TPR_MLP1_2 PF07926.12 EAX99188.1 - 1.4 8.9 37.6 2.2 8.4 16.4 4.4 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein Corona_S2 PF01601.16 EAX99188.1 - 1.6 7.1 7.1 0.52 8.7 3.0 2.1 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein DUF16 PF01519.16 EAX99188.1 - 1.7 9.2 31.5 3.7 8.1 2.7 4.3 3 1 1 4 4 4 0 Protein of unknown function DUF16 DUF4140 PF13600.6 EAX99188.1 - 1.9 9.0 17.8 0.38 11.2 0.3 4.5 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.15 EAX99188.1 - 2 7.9 25.1 0.31 10.6 6.9 3.0 2 1 0 3 3 3 0 Exonuclease VII, large subunit ACP_PD PF04336.12 EAX99188.1 - 2.2 8.7 10.0 3 8.3 0.2 4.0 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF3450 PF11932.8 EAX99188.1 - 2.8 7.2 27.8 0.45 9.8 6.0 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 EAX99188.1 - 3.2 7.1 45.7 3.2 7.0 17.9 4.4 3 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAX99188.1 - 3.3 7.7 30.0 0.091 12.8 2.9 4.6 3 2 2 5 5 5 0 Laminin Domain II VasL PF12486.8 EAX99188.1 - 3.7 7.4 15.5 0.22 11.4 3.4 3.1 3 0 0 3 3 3 0 Type VI secretion system, EvfB, or VasL HMMR_N PF15905.5 EAX99188.1 - 5.8 6.3 39.2 0.53 9.7 6.1 3.1 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF2009 PF09418.10 EAX99188.1 - 5.8 5.9 19.9 0.38 9.8 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2009) CENP-F_leu_zip PF10473.9 EAX99188.1 - 6.6 6.8 37.4 0.24 11.4 5.6 4.5 3 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 EAX99188.1 - 7.1 6.8 17.7 12 6.1 3.1 4.6 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 EAX99188.1 - 7.4 6.9 17.3 1.7 8.9 1.1 4.3 4 0 0 4 4 3 0 Homeobox associated leucine zipper Prominin PF05478.11 EAX99188.1 - 8.8 4.1 28.3 0.23 9.4 1.7 3.7 3 1 1 4 4 4 0 Prominin APG6_N PF17675.1 EAX99188.1 - 9.5 6.8 43.3 0.67 10.5 7.3 4.2 3 1 1 4 4 4 0 Apg6 coiled-coil region LSM PF01423.22 EAX99189.1 - 1.1e-10 41.1 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNase_E_G PF10150.9 EAX99190.1 - 0.012 15.1 0.2 0.93 8.9 0.2 2.3 2 0 0 2 2 2 0 Ribonuclease E/G family ThiF PF00899.21 EAX99191.1 - 1.6e-43 148.8 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 EAX99191.1 - 5.2e-36 124.8 1.6 2.2e-34 119.5 1.6 2.1 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus 2-Hacid_dh_C PF02826.19 EAX99191.1 - 0.073 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAX99191.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase His_Phos_2 PF00328.22 EAX99192.1 - 1.7e-16 60.6 0.1 3.5e-11 43.1 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HSP70 PF00012.20 EAX99193.1 - 8e-240 797.1 11.3 9.6e-240 796.8 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAX99193.1 - 1e-20 73.9 0.1 7.5e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EAX99193.1 - 0.00013 22.3 3.1 0.33 11.4 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EAX99193.1 - 0.00086 19.1 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain NEMO PF11577.8 EAX99193.1 - 0.0028 17.7 1.0 0.0028 17.7 1.0 2.6 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO Hydantoinase_A PF01968.18 EAX99193.1 - 0.048 12.9 0.8 0.47 9.7 0.0 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase ApoO PF09769.9 EAX99193.1 - 0.26 11.3 3.1 9.9 6.1 0.7 3.1 2 1 0 2 2 2 0 Apolipoprotein O AAA_23 PF13476.6 EAX99193.1 - 1.4 9.4 11.5 32 4.9 10.9 2.4 2 1 0 2 2 2 0 AAA domain Phage_holin_6_1 PF09682.10 EAX99193.1 - 2.5 8.6 10.5 0.31 11.5 2.4 2.7 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) FtsJ PF01728.19 EAX99194.1 - 2.2e-69 233.1 0.1 2.5e-69 232.9 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pertussis_S1 PF02917.14 EAX99194.1 - 0.055 13.2 0.1 9.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 GYF PF02213.16 EAX99195.1 - 4.3e-11 42.3 0.5 8.2e-11 41.4 0.5 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EAX99195.1 - 0.00097 18.9 0.3 0.0021 17.8 0.3 1.6 1 0 0 1 1 1 1 GYF domain 2 DUF346 PF03984.13 EAX99195.1 - 0.063 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) OTOS PF15182.6 EAX99198.1 - 0.0086 16.0 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Otospiralin DUF4690 PF15756.5 EAX99199.1 - 5.3e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EAX99199.1 - 0.00026 21.1 1.5 0.00036 20.7 1.5 1.4 1 1 0 1 1 1 1 Podoplanin ODV-E18 PF10717.9 EAX99199.1 - 0.012 15.4 0.6 0.025 14.5 0.6 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5305 PF17231.2 EAX99199.1 - 0.038 13.4 0.1 0.038 13.4 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 EAX99199.1 - 0.082 12.7 0.7 0.23 11.2 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) NVEALA PF14055.6 EAX99199.1 - 0.12 12.4 0.8 0.22 11.5 0.8 1.5 1 0 0 1 1 1 0 NVEALA protein EphA2_TM PF14575.6 EAX99199.1 - 0.2 12.5 1.7 0.51 11.2 1.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 EAX99199.1 - 0.42 11.0 3.2 0.86 10.1 3.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RasGEF PF00617.19 EAX99201.1 - 1.4e-31 110.1 0.0 3.5e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAX99201.1 - 1.9e-09 37.7 0.9 1.9e-09 37.7 0.9 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif PCNA_N PF00705.18 EAX99202.1 - 7e-30 103.3 3.4 7.5e-30 103.2 2.1 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EAX99202.1 - 1.7e-29 102.6 2.3 1.3e-26 93.3 0.0 2.4 2 1 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EAX99202.1 - 6.2e-07 29.1 1.3 7.2e-07 28.9 1.3 1.1 1 0 0 1 1 1 1 Rad9 FPV060 PF17614.2 EAX99202.1 - 0.011 15.1 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 Viral CC-type chemokine Keratin_assoc PF09775.9 EAX99203.1 - 4.7e-12 45.7 2.9 6.5e-12 45.2 2.9 1.3 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF3681 PF12442.8 EAX99203.1 - 0.0046 17.4 1.3 0.0066 16.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3681) GPI2 PF06432.11 EAX99203.1 - 0.042 13.3 2.2 0.046 13.2 2.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3792 PF12670.7 EAX99203.1 - 0.087 13.0 4.8 0.04 14.1 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) TerC PF03741.16 EAX99203.1 - 0.33 10.6 7.1 0.4 10.3 4.1 1.9 1 1 1 2 2 2 0 Integral membrane protein TerC family DUF2070 PF09843.9 EAX99203.1 - 0.88 7.8 5.3 1.1 7.5 5.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AC_N PF16214.5 EAX99203.1 - 1.2 8.2 4.4 1.3 8.0 4.4 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region LRR_5 PF13306.6 EAX99204.1 - 6.6e-199 650.1 76.6 1.1e-28 99.8 3.6 10.6 1 1 8 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99204.1 - 1e-49 166.1 0.2 0.008 15.9 0.0 15.1 12 3 4 16 16 16 12 Leucine rich repeat LRR_4 PF12799.7 EAX99204.1 - 4.6e-16 58.7 9.4 7.8 7.1 0.0 13.6 14 0 0 14 14 14 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX99204.1 - 2.3 9.1 13.6 19 6.3 0.0 7.3 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 EAX99205.1 - 1.2e-27 97.0 0.0 1.7e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99205.1 - 2.4e-15 56.5 0.0 3.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX99205.1 - 4.7e-09 35.5 0.0 4.7e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EAX99205.1 - 0.0014 18.6 1.1 0.16 11.8 0.1 2.9 2 2 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX99205.1 - 0.019 14.6 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 EAX99205.1 - 0.022 13.7 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Com_YlbF PF06133.11 EAX99205.1 - 1.5 9.5 8.9 3.5 8.3 8.9 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DDR PF08841.10 EAX99206.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BRO1 PF03097.18 EAX99208.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain HECT PF00632.25 EAX99209.1 - 3.7e-57 194.2 0.0 1e-56 192.7 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CUB PF00431.20 EAX99209.1 - 0.064 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 CUB domain SPRY PF00622.28 EAX99209.1 - 0.1 12.7 0.2 0.36 10.9 0.2 2.0 1 1 0 1 1 1 0 SPRY domain AAA_6 PF12774.7 EAX99210.1 - 3e-145 483.3 0.0 1.1e-144 481.5 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EAX99210.1 - 5.1e-128 428.2 7.3 5.1e-128 428.2 7.3 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EAX99210.1 - 1.2e-125 419.7 10.7 1.2e-125 419.7 10.7 6.6 8 1 0 8 8 8 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EAX99210.1 - 2e-97 325.6 0.0 7.5e-96 320.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EAX99210.1 - 9.5e-83 277.9 4.4 4.5e-82 275.7 4.4 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EAX99210.1 - 8.2e-75 250.7 1.6 8.2e-75 250.7 1.6 4.0 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EAX99210.1 - 8.5e-65 217.6 1.8 3.5e-60 202.6 0.0 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EAX99210.1 - 4.5e-51 172.9 0.3 1.1e-50 171.7 0.3 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAX99210.1 - 7.8e-46 155.0 0.0 1.4e-42 144.5 0.0 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EAX99210.1 - 5.7e-33 114.4 15.8 6.7e-33 114.1 14.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EAX99210.1 - 4e-30 104.5 0.3 2.5e-29 102.0 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EAX99210.1 - 8.1e-22 77.7 0.0 0.00025 21.0 0.0 6.1 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EAX99210.1 - 2.9e-15 56.3 0.0 1.1e-14 54.5 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EAX99210.1 - 4.2e-07 30.5 1.2 1.6 9.1 0.0 5.6 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX99210.1 - 9.2e-05 22.9 5.5 1.8 8.9 0.0 5.6 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 EAX99210.1 - 0.0041 17.4 0.3 18 5.6 0.0 5.5 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EAX99210.1 - 0.027 14.8 0.0 7.3 7.0 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 EAX99210.1 - 0.068 13.7 0.0 4.2 7.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EAX99210.1 - 0.12 12.3 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EAX99210.1 - 0.14 12.0 2.0 3.2 7.6 0.2 3.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EAX99210.1 - 1.2 8.8 9.0 8.4 6.1 0.1 3.9 4 0 0 4 4 3 0 AAA domain RNA_polI_A14 PF08203.11 EAX99210.1 - 7.5 7.3 9.4 4.6 8.0 0.1 4.7 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 CLASP_N PF12348.8 EAX99211.1 - 4.7e-25 88.5 3.3 1.7e-21 76.9 0.1 2.8 3 0 0 3 3 3 2 CLASP N terminal ANAPC3 PF12895.7 EAX99211.1 - 0.023 14.9 0.1 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.22 EAX99211.1 - 0.048 13.9 2.5 16 6.1 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 EAX99211.1 - 0.4 10.7 7.8 15 5.6 0.0 4.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ras PF00071.22 EAX99212.1 - 1e-43 148.7 0.1 1.2e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99212.1 - 1.1e-31 109.6 0.2 1.5e-31 109.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99212.1 - 1e-15 57.6 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX99212.1 - 1.9e-06 27.5 0.5 0.00016 21.3 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX99212.1 - 2e-06 27.8 0.1 3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99212.1 - 3.5e-06 26.5 0.1 4.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX99212.1 - 2.4e-05 24.3 0.0 0.2 11.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAX99212.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX99212.1 - 0.00037 20.0 0.2 0.033 13.7 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAX99212.1 - 0.00049 20.2 0.1 0.001 19.2 0.1 1.7 1 1 0 1 1 1 1 Dynamin family PduV-EutP PF10662.9 EAX99212.1 - 0.0045 16.7 0.1 0.068 12.9 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX99212.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Filament PF00038.21 EAX99213.1 - 2.4e-05 24.1 24.9 2.4e-05 24.1 24.9 6.0 2 1 4 6 6 6 4 Intermediate filament protein GRIP PF01465.20 EAX99213.1 - 0.00033 20.5 0.0 0.00085 19.2 0.0 1.8 1 0 0 1 1 1 1 GRIP domain Lebercilin PF15619.6 EAX99213.1 - 0.0019 17.9 9.1 0.0019 17.9 9.1 7.8 1 1 4 7 7 7 3 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 EAX99213.1 - 0.0032 18.0 24.9 0.0032 18.0 24.9 6.2 1 1 5 6 6 6 2 Fez1 CALCOCO1 PF07888.11 EAX99213.1 - 0.0038 16.2 33.5 0.0038 16.2 33.5 4.4 1 1 3 4 4 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 EAX99213.1 - 0.013 13.9 161.6 0.0062 15.0 45.8 4.6 1 1 3 4 4 4 0 Mitotic checkpoint protein Spc7 PF08317.11 EAX99213.1 - 0.023 13.6 159.6 0.018 13.9 12.3 7.2 1 1 4 6 6 6 0 Spc7 kinetochore protein CinA_KH PF18146.1 EAX99213.1 - 0.73 10.0 4.4 1.4 9.1 0.4 3.8 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain ATG16 PF08614.11 EAX99213.1 - 0.93 9.7 150.3 0.025 14.8 38.4 8.0 1 1 7 8 8 8 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EAX99213.1 - 1.8 8.8 144.6 0.35 11.1 17.6 9.3 2 1 6 9 9 9 0 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 EAX99213.1 - 6.1 7.1 140.0 0.22 11.8 27.5 9.2 1 1 8 9 9 9 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 EAX99213.1 - 6.7 6.0 125.5 0.13 11.6 13.5 6.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) CDP-OH_P_transf PF01066.21 EAX99214.1 - 6.2e-17 62.1 0.3 6.2e-17 62.1 0.3 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_14 PF01373.17 EAX99215.1 - 1.8e-78 264.2 1.9 9.3e-78 261.9 1.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 EAX99215.1 - 0.004 16.8 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EAX99215.1 - 0.046 13.1 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase RuvC PF02075.17 EAX99216.1 - 0.19 11.6 4.2 0.97 9.3 0.2 2.8 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC DUF641 PF04859.12 EAX99217.1 - 0.015 15.6 23.2 0.033 14.5 2.2 4.5 4 1 0 4 4 4 0 Plant protein of unknown function (DUF641) ACT_5 PF13710.6 EAX99217.1 - 0.7 9.8 5.3 7.1 6.6 0.1 4.2 4 0 0 4 4 4 0 ACT domain HrpB7 PF09486.10 EAX99217.1 - 2 8.8 9.9 13 6.1 0.1 3.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 EAX99217.1 - 2.9 8.4 31.4 0.88 10.1 5.6 7.1 8 1 0 8 8 8 0 Nucleopolyhedrovirus P10 protein PKcGMP_CC PF16808.5 EAX99217.1 - 5 7.1 21.3 0.063 13.1 3.8 5.4 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PI3_PI4_kinase PF00454.27 EAX99218.1 - 2.1e-32 112.9 0.3 1.6e-29 103.5 0.3 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EAX99218.1 - 7.5e-16 58.1 1.1 1.8e-15 56.8 1.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Rhodanese PF00581.20 EAX99219.1 - 4.1e-14 53.0 0.0 7.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Aa_trans PF01490.18 EAX99220.1 - 2.5e-43 148.3 35.7 3.2e-43 148.0 35.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Curto_V3 PF07436.11 EAX99220.1 - 0.42 11.0 2.6 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Curtovirus V3 protein DUF2517 PF10725.9 EAX99220.1 - 1.7 8.4 4.7 3.9 7.3 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2517) Adeno_E3_CR2 PF02439.15 EAX99221.1 - 0.1 12.4 4.3 0.21 11.4 4.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EAX99221.1 - 0.45 10.5 2.3 0.9 9.5 2.3 1.4 1 0 0 1 1 1 0 Syndecan domain CK_II_beta PF01214.18 EAX99222.1 - 2.7e-44 151.2 0.4 3e-44 151.0 0.4 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CCDC24 PF15669.5 EAX99223.1 - 0.00012 22.0 3.5 0.0031 17.4 3.5 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family EF-hand_4 PF12763.7 EAX99223.1 - 0.016 15.2 0.1 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Csc2 PF18320.1 EAX99223.1 - 0.024 13.6 0.4 0.066 12.2 0.1 1.7 1 1 1 2 2 2 0 Csc2 Crispr Biotin_carb_C PF02785.19 EAX99223.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 Biotin carboxylase C-terminal domain Chordopox_L2 PF05803.12 EAX99224.1 - 1.7 8.6 4.4 1.4 8.8 1.3 2.5 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Fez1 PF06818.15 EAX99224.1 - 8.5 6.8 50.0 1.1 9.7 9.9 3.1 2 1 1 3 3 3 0 Fez1 Sigma54_activ_2 PF14532.6 EAX99225.1 - 0.022 14.9 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Pkinase PF00069.25 EAX99226.1 - 7.9e-57 192.6 0.1 1.1e-56 192.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99226.1 - 9.6e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99226.1 - 3.2e-06 26.7 0.0 0.0002 20.8 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAX99226.1 - 0.00076 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX99226.1 - 0.0023 16.8 0.0 0.013 14.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EAX99226.1 - 0.0025 17.8 0.0 0.0049 16.8 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAX99226.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EAX99226.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EAX99226.1 - 0.055 12.4 3.0 0.035 13.0 0.3 2.1 2 1 0 2 2 2 0 Haspin like kinase domain DUF3839 PF12943.7 EAX99227.1 - 1.4e-157 522.4 13.5 1.7e-157 522.1 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAX99227.1 - 0.023 14.9 0.1 0.071 13.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAX99227.1 - 0.05 14.0 1.3 0.069 13.6 0.2 1.8 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAX99227.1 - 0.38 11.2 6.5 1.4 9.5 0.4 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YmaF PF12788.7 EAX99228.1 - 0.18 12.4 1.8 6.6 7.3 0.1 2.1 1 1 0 1 1 1 0 YmaF family Phage_fiber PF03335.13 EAX99228.1 - 1.6 9.1 7.9 2.7 8.4 0.3 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat PTR PF12789.7 EAX99229.1 - 1.3e-51 172.5 31.5 1.5e-34 117.8 15.7 6.5 5 2 1 6 6 6 3 Phage tail repeat like DUF4795 PF16043.5 EAX99229.1 - 0.024 14.2 21.7 0.0099 15.5 6.6 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) UCH PF00443.29 EAX99230.1 - 1.2e-37 129.8 0.3 3e-37 128.5 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAX99230.1 - 1.5e-11 44.4 0.0 2.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EAX99230.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family HALZ PF02183.18 EAX99231.1 - 0.049 13.9 0.5 0.049 13.9 0.5 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1796 PF08795.10 EAX99231.1 - 0.051 13.5 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) bZIP_1 PF00170.21 EAX99231.1 - 0.073 13.2 0.9 0.83 9.8 0.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EAX99231.1 - 2 8.5 5.9 0.25 11.5 0.9 1.9 2 1 0 2 2 2 0 Basic region leucine zipper YaeQ PF07152.12 EAX99232.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 YaeQ protein Ribosomal_L22 PF00237.19 EAX99233.1 - 1e-21 77.1 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ank_2 PF12796.7 EAX99234.1 - 4.6e-75 248.2 0.1 1.9e-14 54.0 0.0 4.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99234.1 - 2.9e-41 138.2 0.0 2.1e-05 24.8 0.0 7.6 7 1 1 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX99234.1 - 4e-40 135.3 0.0 1e-07 32.1 0.0 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99234.1 - 1.8e-36 124.0 0.0 5.1e-11 42.9 0.0 5.5 3 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99234.1 - 3.3e-34 113.0 0.0 0.001 19.4 0.0 7.4 8 0 0 8 8 8 6 Ankyrin repeat L_protein_N PF15518.6 EAX99234.1 - 2.5e-07 30.4 0.1 0.18 11.6 0.0 4.6 2 1 3 5 5 5 3 L protein N-terminus mTERF PF02536.14 EAX99234.1 - 5e-06 25.7 0.0 0.0016 17.4 0.0 2.2 1 1 0 2 2 2 2 mTERF DUF1897 PF09005.10 EAX99234.1 - 0.0096 15.4 0.0 1.5e+02 2.0 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) DUF3083 PF11281.8 EAX99234.1 - 0.011 15.2 0.0 5.4 6.3 0.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3083) Pox_E8 PF03394.13 EAX99234.1 - 0.17 11.4 0.3 43 3.5 0.0 3.9 1 1 4 5 5 5 0 Poxvirus E8 protein IBN_N PF03810.19 EAX99235.1 - 0.059 13.3 1.7 0.13 12.2 0.1 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain RRM_1 PF00076.22 EAX99236.1 - 0.0015 18.3 0.2 0.0028 17.4 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CEP76-C2 PF15627.6 EAX99237.1 - 0.0028 17.2 0.0 0.0098 15.5 0.0 1.8 1 1 0 1 1 1 1 CEP76 C2 domain 2Fe-2S_thioredx PF01257.19 EAX99238.1 - 6.9e-45 152.5 0.1 8.3e-45 152.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin TAP42 PF04177.12 EAX99239.1 - 5.1e-32 111.3 14.7 1.2e-30 106.8 14.7 2.0 1 1 0 1 1 1 1 TAP42-like family Ank_2 PF12796.7 EAX99240.1 - 3.7e-38 130.0 7.2 1.5e-18 67.1 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99240.1 - 3e-30 104.2 9.9 3.6e-11 43.4 0.4 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99240.1 - 4.8e-22 75.7 1.4 1.4e-05 25.1 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAX99240.1 - 1.2e-21 76.5 3.4 9.3e-08 32.2 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99240.1 - 1.7e-18 66.1 0.5 3.6e-05 24.0 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeat DUF4261 PF14080.6 EAX99240.1 - 0.008 16.3 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4261) IF4E PF01652.18 EAX99241.1 - 7.7e-15 55.0 0.0 9.5e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NTF2 PF02136.20 EAX99242.1 - 1.3e-09 38.6 0.0 1.6e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 EAX99242.1 - 0.0057 15.9 0.5 0.023 13.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4518) Ank_2 PF12796.7 EAX99243.1 - 9.3e-213 689.5 14.3 4.6e-21 75.2 0.1 12.9 1 1 14 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99243.1 - 1.2e-150 484.0 0.0 3.1e-05 24.2 0.0 23.1 24 0 0 24 24 24 22 Ankyrin repeat Ank_3 PF13606.6 EAX99243.1 - 3.5e-124 389.5 0.0 0.00046 20.4 0.0 23.4 24 0 0 24 24 24 22 Ankyrin repeat Ank_4 PF13637.6 EAX99243.1 - 6e-120 390.2 0.0 1.1e-09 38.6 0.0 14.9 10 3 3 15 15 15 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99243.1 - 7.5e-120 389.4 3.1 4.2e-08 33.3 0.0 22.5 1 1 22 23 23 23 22 Ankyrin repeats (many copies) DUF3083 PF11281.8 EAX99243.1 - 3.5e-11 43.0 0.1 1.3 8.3 0.0 8.7 1 1 8 12 12 12 4 Protein of unknown function (DUF3083) mTERF PF02536.14 EAX99243.1 - 4.1e-09 35.8 0.1 18 4.1 0.0 8.6 4 1 3 9 9 9 0 mTERF Ribosomal_L17 PF01196.19 EAX99243.1 - 1e-06 29.5 0.0 32 5.5 0.0 8.1 3 2 2 5 5 5 0 Ribosomal protein L17 GATase_7 PF13537.6 EAX99243.1 - 5.2e-06 26.4 0.0 32 4.5 0.0 9.2 11 0 0 11 11 11 0 Glutamine amidotransferase domain Rad4 PF03835.15 EAX99243.1 - 0.00099 18.8 12.0 72 3.0 0.1 9.7 7 3 4 12 12 12 0 Rad4 transglutaminase-like domain Pox_E8 PF03394.13 EAX99243.1 - 0.0038 16.8 5.3 1.3e+02 1.9 0.0 9.2 3 3 8 13 13 13 0 Poxvirus E8 protein OSCP PF00213.18 EAX99244.1 - 0.0041 17.3 0.9 0.011 15.9 0.1 1.9 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit UBA_e1_thiolCys PF10585.9 EAX99244.1 - 0.045 13.7 1.9 0.064 13.2 0.3 1.9 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site ComZ PF10815.8 EAX99244.1 - 0.064 13.3 0.8 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 ComZ DNA_repr_REX1B PF14966.6 EAX99244.1 - 0.13 12.9 0.1 4.9 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA repair REX1-B PNP_UDP_1 PF01048.20 EAX99245.1 - 5.9e-42 143.5 0.0 6.9e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily TSP9 PF11493.8 EAX99245.1 - 0.059 14.1 0.0 1.8 9.3 0.0 2.3 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 ChAPs PF09295.10 EAX99245.1 - 0.092 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) RRM_1 PF00076.22 EAX99246.1 - 2.1e-13 49.9 3.0 1.2e-09 37.8 0.6 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAX99246.1 - 3.7e-05 23.3 0.3 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 EAX99246.1 - 0.0058 16.5 1.1 1.4 8.8 0.1 3.4 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EAX99246.1 - 0.024 14.6 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MYCBPAP PF14646.6 EAX99247.1 - 8.9e-41 140.2 8.3 1.2e-17 64.0 0.1 3.4 3 1 1 4 4 4 3 MYCBP-associated protein family USP7_ICP0_bdg PF12436.8 EAX99247.1 - 0.0013 18.1 0.8 0.0035 16.7 0.2 2.0 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 OAD_gamma PF04277.13 EAX99247.1 - 2.3 8.8 6.1 5.4 7.7 5.5 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-MYST PF17772.1 EAX99248.1 - 3.3e-20 71.4 2.9 5.9e-20 70.6 2.9 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain MOZ_SAS PF01853.18 EAX99248.1 - 2.3e-12 47.0 0.6 5.4e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 MOZ/SAS family Tudor-knot PF11717.8 EAX99248.1 - 1.4e-05 24.8 0.1 2.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 EAX99248.1 - 0.0062 17.3 0.9 0.019 15.8 0.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAX99248.1 - 0.053 13.8 2.8 0.14 12.4 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_47 PF01532.20 EAX99249.1 - 2.5e-10 39.9 9.2 0.0012 17.9 0.5 3.4 1 1 2 3 3 3 3 Glycosyl hydrolase family 47 UvrD-helicase PF00580.21 EAX99250.1 - 1.4e-59 202.2 2.2 1.4e-59 202.2 2.2 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EAX99250.1 - 6.8e-42 144.1 4.5 6.8e-42 144.1 4.5 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAX99250.1 - 1.1e-31 110.1 0.3 1.2e-30 106.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EAX99250.1 - 3.5e-08 33.1 0.2 3.4e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EAX99250.1 - 4.3e-08 33.1 0.0 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 EAX99250.1 - 1.5e-05 24.7 1.3 0.0013 18.4 0.2 3.9 4 1 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 EAX99250.1 - 0.0002 21.2 0.2 0.14 11.9 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase GP24_25 PF17388.2 EAX99250.1 - 0.006 16.6 0.6 0.96 9.4 0.3 2.8 2 0 0 2 2 2 1 Tail assembly gene products 24 & 25 Erf4 PF10256.9 EAX99250.1 - 0.18 11.9 2.1 0.72 10.0 0.9 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family LRR_5 PF13306.6 EAX99251.1 - 3.6e-36 123.9 35.4 3.1e-20 72.4 13.7 5.1 1 1 4 6 6 6 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99251.1 - 7.4e-06 25.6 2.0 0.89 9.4 0.3 4.5 1 1 4 5 5 5 5 Leucine rich repeat SH3_13 PF18335.1 EAX99251.1 - 0.032 14.1 0.2 0.85 9.5 0.0 2.6 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain LRR_4 PF12799.7 EAX99251.1 - 0.19 12.2 9.1 1.5 9.3 1.4 4.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) zf-Tim10_DDP PF02953.15 EAX99251.1 - 4.7 6.9 6.9 6.1 6.6 2.5 2.7 1 1 1 2 2 2 0 Tim10/DDP family zinc finger LRR_5 PF13306.6 EAX99252.1 - 9.6e-36 122.6 45.2 1.1e-15 57.7 7.1 5.2 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EAX99252.1 - 6.8e-07 29.5 9.4 1.6 9.3 0.0 7.4 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX99252.1 - 2.4e-05 24.0 0.0 5.8 6.8 0.0 5.6 4 1 2 6 6 6 1 Leucine rich repeat Oxidored_FMN PF00724.20 EAX99253.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 EAX99254.1 - 3.2e-17 62.8 0.0 3.9e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ARA70 PF12489.8 EAX99256.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Pox_A32 PF04665.12 EAX99257.1 - 7.9e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX99257.1 - 0.0058 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX99257.1 - 0.0096 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX99257.1 - 0.054 12.7 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX99257.1 - 0.099 12.9 2.1 0.24 11.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Ank_4 PF13637.6 EAX99258.1 - 5.1e-12 46.1 0.7 8.2e-07 29.5 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99258.1 - 1.1e-11 44.6 0.2 2.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX99258.1 - 3.4e-11 43.6 0.4 4.1e-11 43.3 0.4 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99258.1 - 8e-10 38.1 0.3 9.9e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX99258.1 - 1.3e-05 25.3 0.8 0.0057 17.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PAZ_siRNAbind PF12212.8 EAX99258.1 - 0.044 13.6 0.2 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 PAZ domain DUF3447 PF11929.8 EAX99258.1 - 0.093 12.7 3.2 0.1 12.6 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DUF3447 PF11929.8 EAX99259.1 - 1.6e-36 124.1 5.6 1.6e-36 124.1 5.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99259.1 - 0.00034 21.1 0.1 0.0015 19.0 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RL PF17797.1 EAX99259.1 - 0.009 15.9 2.1 0.076 13.0 0.5 2.5 2 1 0 2 2 2 1 RL domain Ank_3 PF13606.6 EAX99259.1 - 0.019 15.5 0.5 1.1e+02 3.9 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat RE_SinI PF09570.10 EAX99259.1 - 0.073 12.3 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease Ank_4 PF13637.6 EAX99260.1 - 6.5e-30 103.1 6.7 5.1e-10 39.7 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99260.1 - 1.5e-29 101.1 5.6 1.3e-07 31.8 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 EAX99260.1 - 3.7e-28 97.9 8.6 1.5e-18 67.1 2.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99260.1 - 6.6e-21 72.2 2.4 8.6e-05 22.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAX99260.1 - 8.6e-19 67.4 2.2 4.1e-09 36.5 0.2 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) YcxB PF14317.6 EAX99260.1 - 4.8e-06 26.2 0.1 0.91 9.3 0.0 3.1 3 0 0 3 3 3 2 YcxB-like protein DUF3130 PF11328.8 EAX99260.1 - 0.00041 20.5 0.1 0.23 11.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3130 Importin_rep_5 PF18816.1 EAX99260.1 - 0.26 11.6 1.4 16 5.9 0.0 2.7 2 1 0 2 2 2 0 Importin repeat SAB PF04382.13 EAX99260.1 - 3.2 7.9 3.9 93 3.2 0.0 3.5 4 0 0 4 4 4 0 SAB domain Ank_2 PF12796.7 EAX99261.1 - 6.2e-59 196.6 29.8 8.9e-17 61.5 1.6 5.9 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99261.1 - 1.1e-55 183.8 7.7 2.9e-07 30.6 0.1 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EAX99261.1 - 2.8e-53 177.6 16.8 3.7e-09 36.9 0.3 9.6 3 1 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99261.1 - 1.4e-44 144.9 17.9 7.7e-06 25.9 0.1 10.6 11 0 0 11 11 11 8 Ankyrin repeat DUF3447 PF11929.8 EAX99261.1 - 3.8e-37 126.1 11.3 3.3e-36 123.1 5.9 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX99261.1 - 3.7e-36 122.7 10.9 1.6e-11 44.2 0.1 7.7 4 2 2 8 8 8 6 Ankyrin repeats (many copies) YcxB PF14317.6 EAX99261.1 - 1.5e-06 27.8 1.6 1.9 8.3 0.0 4.5 4 1 1 5 5 5 3 YcxB-like protein KdgM PF06178.13 EAX99261.1 - 0.0003 20.5 3.9 0.61 9.7 0.2 3.2 1 1 1 3 3 3 3 Oligogalacturonate-specific porin protein (KdgM) DUF5064 PF16703.5 EAX99261.1 - 0.00046 20.7 1.4 0.49 10.9 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5064) DUF3130 PF11328.8 EAX99261.1 - 0.15 12.4 5.1 17 5.7 0.0 4.3 2 1 2 5 5 5 0 Protein of unknown function (DUF3130 RL PF17797.1 EAX99261.1 - 0.25 11.3 13.4 0.33 10.9 0.5 5.7 5 2 1 6 6 6 0 RL domain DUF640 PF04852.12 EAX99261.1 - 0.46 10.6 6.4 9 6.5 0.1 5.3 7 1 1 9 9 9 0 Protein of unknown function (DUF640) Sec8_exocyst PF04048.14 EAX99262.1 - 0.0099 15.8 7.8 0.0099 15.8 7.8 5.7 4 2 1 5 5 5 1 Sec8 exocyst complex component specific domain Fe-S_assembly PF04384.13 EAX99262.1 - 1.7 9.4 8.4 5.7 7.6 0.4 4.1 4 0 0 4 4 4 0 Iron-sulphur cluster assembly YhhN PF07947.14 EAX99264.1 - 1.7e-07 31.0 17.4 2e-07 30.8 17.4 1.1 1 0 0 1 1 1 1 YhhN family YtxH PF12732.7 EAX99265.1 - 0.00097 19.6 0.4 0.0013 19.3 0.4 1.1 1 0 0 1 1 1 1 YtxH-like protein Apolipoprotein PF01442.18 EAX99265.1 - 0.0043 17.0 2.2 0.0047 16.8 2.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Arm-DNA-bind_5 PF17293.2 EAX99265.1 - 0.014 15.8 1.1 0.015 15.7 1.1 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain CiPC PF15800.5 EAX99265.1 - 0.038 13.7 0.8 0.048 13.4 0.8 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian CREPT PF16566.5 EAX99265.1 - 0.041 14.1 1.7 0.042 14.0 1.7 1.0 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AcylCoA_dehyd_C PF12186.8 EAX99265.1 - 0.11 12.6 1.3 0.14 12.3 1.3 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Beta-lactamase PF00144.24 EAX99266.1 - 1.1e-34 120.1 0.0 1.7e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Ring_hydroxyl_B PF00866.18 EAX99267.1 - 0.025 14.6 1.2 0.032 14.3 1.0 1.3 1 1 0 1 1 1 0 Ring hydroxylating beta subunit CorA PF01544.18 EAX99267.1 - 0.099 11.9 0.9 0.13 11.6 0.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 EAX99267.1 - 0.3 11.0 4.0 1.4 8.9 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit FAM195 PF14799.6 EAX99267.1 - 0.64 10.4 5.2 2.6 8.4 5.2 2.0 1 1 0 1 1 1 0 FAM195 family DUF1525 PF07511.11 EAX99267.1 - 3 8.0 6.2 0.35 11.0 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Ras PF00071.22 EAX99268.1 - 3e-32 111.5 0.0 3.5e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99268.1 - 3.1e-25 88.7 0.0 4.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99268.1 - 7.9e-13 48.2 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAX99268.1 - 2.6e-05 24.2 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EAX99268.1 - 3.5e-05 23.6 0.1 0.12 12.1 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAX99268.1 - 5.4e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAX99268.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EAX99268.1 - 0.0025 17.4 0.1 0.024 14.1 0.0 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EAX99268.1 - 0.0037 17.3 0.0 0.0054 16.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX99268.1 - 0.02 15.2 0.1 0.096 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 EAX99268.1 - 0.029 13.8 0.0 0.037 13.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EAX99268.1 - 0.029 14.1 0.2 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAX99268.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1_Xtn PF16897.5 EAX99268.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA PF00004.29 EAX99268.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAX99268.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 EAX99268.1 - 0.071 13.2 0.0 0.54 10.4 0.0 2.1 1 1 1 2 2 2 0 Torsin G-alpha PF00503.20 EAX99268.1 - 0.084 12.0 0.2 0.41 9.7 0.2 2.0 1 1 0 1 1 1 0 G-protein alpha subunit IstB_IS21 PF01695.17 EAX99268.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAX99268.1 - 0.19 11.1 0.0 0.5 9.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fringe PF02434.16 EAX99269.1 - 0.00091 18.7 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like ubiquitin PF00240.23 EAX99270.1 - 1.1e-17 63.6 1.7 2.3e-12 46.5 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 EAX99270.1 - 8.2e-11 41.6 0.9 8.5e-09 35.1 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAX99270.1 - 1.6e-05 24.8 0.3 0.23 11.4 0.1 2.4 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAX99270.1 - 0.001 19.4 0.5 0.0061 16.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain TolA_bind_tri PF16331.5 EAX99271.1 - 0.00023 21.2 18.4 0.07 13.2 0.3 3.6 3 0 0 3 3 3 2 TolA binding protein trimerisation ATG16 PF08614.11 EAX99271.1 - 0.0046 17.2 28.9 0.29 11.3 2.0 3.1 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.12 EAX99271.1 - 0.21 11.7 3.3 15 5.8 0.3 3.5 3 2 0 3 3 3 0 MbeD/MobD like TSC22 PF01166.18 EAX99271.1 - 0.27 11.6 17.6 0.95 9.8 0.1 5.0 3 1 2 5 5 5 0 TSC-22/dip/bun family Sec8_exocyst PF04048.14 EAX99271.1 - 0.44 10.4 20.3 0.3 11.0 4.9 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Fzo_mitofusin PF04799.13 EAX99271.1 - 0.59 9.7 18.6 0.057 13.0 4.4 3.3 2 1 1 3 3 3 0 fzo-like conserved region LOH1CR12 PF10158.9 EAX99271.1 - 0.63 10.1 10.0 0.055 13.5 1.9 2.7 2 1 1 3 3 3 0 Tumour suppressor protein YabA PF06156.13 EAX99271.1 - 0.79 10.4 25.0 0.36 11.5 0.7 3.6 2 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 EAX99271.1 - 0.85 9.7 32.2 13 5.8 17.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 EAX99271.1 - 1.1 8.5 19.2 1.9 7.7 11.4 2.5 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.11 EAX99271.1 - 1.5 9.5 20.7 0.43 11.2 4.4 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EAX99271.1 - 1.5 9.3 33.9 6.1 7.4 1.8 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 EAX99271.1 - 1.6 9.2 27.9 0.84 10.1 8.8 3.0 1 1 2 3 3 3 0 Fez1 DUF4140 PF13600.6 EAX99271.1 - 2.1 8.8 21.1 0.6 10.6 0.2 4.2 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 EAX99271.1 - 3 5.7 22.5 1.1 7.1 10.0 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 EAX99271.1 - 4.4 7.5 25.2 8.2 6.7 22.2 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein DivIC PF04977.15 EAX99271.1 - 5.7 6.8 30.6 0.16 11.7 1.2 5.2 2 2 2 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 EAX99271.1 - 6.8 6.9 26.7 0.67 10.1 1.1 5.0 4 1 0 4 4 4 0 bZIP transcription factor Telomere_reg-2 PF10193.9 EAX99271.1 - 7 7.1 8.0 2.5 8.6 2.3 2.9 2 1 1 3 3 3 0 Telomere length regulation protein DUF4407 PF14362.6 EAX99271.1 - 7.6 5.8 23.4 1.1e+03 -1.3 23.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1515 PF07439.11 EAX99271.1 - 8.4 6.5 6.8 3.5 7.7 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Ank_4 PF13637.6 EAX99272.1 - 4.6e-21 74.9 0.3 4.7e-12 46.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99272.1 - 3.6e-20 71.4 0.5 1e-06 28.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAX99272.1 - 6.6e-19 68.3 0.6 2.4e-08 34.5 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99272.1 - 5.7e-15 55.2 1.4 5.6e-10 39.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99272.1 - 6.2e-15 53.8 0.4 3e-05 24.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 EAX99273.1 - 1.7e-15 56.7 11.5 1.7e-15 56.7 11.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Rhomboid PF01694.22 EAX99274.1 - 3.1e-33 114.9 18.3 5.2e-33 114.2 18.3 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EAX99274.1 - 0.036 14.6 3.0 0.1 13.2 2.5 2.1 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DUF5518 PF17647.1 EAX99274.1 - 5.9 7.1 20.5 0.68 10.1 14.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Myb_DNA-binding PF00249.31 EAX99275.1 - 3.1e-25 88.1 0.2 3.2e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99275.1 - 2.9e-20 72.3 0.0 2.7e-11 43.5 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX99275.1 - 2.6e-06 27.2 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX99275.1 - 0.00016 21.6 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 EAX99275.1 - 0.0053 16.9 0.2 2.3 8.5 0.0 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EAX99275.1 - 0.15 12.2 0.2 5.6 7.1 0.2 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 EAX99276.1 - 1.1e-25 89.6 0.3 3.1e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99276.1 - 3.9e-20 71.9 0.0 4.5e-12 46.0 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAX99276.1 - 3.6e-05 23.6 0.1 0.033 14.1 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAX99276.1 - 0.00023 21.2 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 EAX99276.1 - 0.0066 16.6 0.2 2 8.6 0.0 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Hydrolase_4 PF12146.8 EAX99277.1 - 2.6e-12 46.5 0.0 1.5e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAX99277.1 - 2.9e-07 31.3 0.0 5.4e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAX99277.1 - 4.3e-07 29.8 0.1 7.2e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EAX99277.1 - 0.0048 16.5 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EAX99277.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Pkinase PF00069.25 EAX99278.1 - 2.9e-18 66.2 0.0 5.5e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99278.1 - 7e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99278.1 - 0.00073 18.9 0.0 0.0087 15.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like WD40 PF00400.32 EAX99278.1 - 0.025 15.4 2.6 1.2 10.2 0.8 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat AAA_33 PF13671.6 EAX99278.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EAX99280.1 - 0.015 15.4 4.7 0.018 15.2 4.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COPIIcoated_ERV PF07970.12 EAX99280.1 - 0.066 13.1 0.9 0.076 12.9 0.9 1.0 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter PKI PF02827.16 EAX99280.1 - 0.1 12.8 0.4 0.17 12.1 0.3 1.5 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor TTL PF03133.15 EAX99281.1 - 1e-41 143.0 0.0 1.7e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX99281.1 - 1.1e-08 34.7 0.0 0.017 14.4 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX99281.1 - 5.4e-07 29.1 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX99281.1 - 0.0027 17.8 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain IFN-gamma PF00714.17 EAX99281.1 - 0.087 12.7 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Interferon gamma Hydrolase_4 PF12146.8 EAX99282.1 - 4e-15 55.7 0.0 2.9e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 EAX99282.1 - 1.2e-06 27.5 0.0 2.7e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EAX99282.1 - 8e-06 25.7 0.1 0.00022 21.0 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EAX99282.1 - 5.5e-05 22.9 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EAX99282.1 - 0.0008 18.9 0.0 0.0025 17.3 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EAX99282.1 - 0.0011 19.7 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EAX99282.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EAX99282.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 EAX99282.1 - 0.086 11.5 0.0 0.11 11.1 0.0 1.3 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Radial_spoke PF04712.12 EAX99282.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein gp37_C PF12604.8 EAX99283.1 - 0.032 13.9 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal EAV_GP5 PF15981.5 EAX99283.1 - 0.087 13.2 1.7 0.21 12.0 0.5 2.0 1 1 1 2 2 2 0 Envelope glycoprotein GP 5 of equine arteritis virus PapC_N PF13954.6 EAX99284.1 - 0.038 14.0 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 PapC N-terminal domain Pkinase PF00069.25 EAX99286.1 - 2.2e-65 220.6 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99286.1 - 1.2e-43 149.3 0.0 1.4e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAX99286.1 - 5e-06 25.7 0.7 8.9e-06 24.9 0.7 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAX99286.1 - 3.5e-05 23.8 0.0 0.014 15.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAX99286.1 - 0.00015 21.2 0.0 0.097 12.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like L_protein_N PF15518.6 EAX99286.1 - 0.00032 20.5 0.1 0.00059 19.6 0.1 1.4 1 0 0 1 1 1 1 L protein N-terminus Kdo PF06293.14 EAX99286.1 - 0.0017 17.8 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE9 PF17153.4 EAX99286.1 - 0.032 14.4 0.2 0.057 13.6 0.2 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular UPF0154 PF03672.13 EAX99286.1 - 0.065 13.3 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3447 PF11929.8 EAX99287.1 - 9.4e-11 41.5 0.1 9.4e-11 41.5 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) SWIRM PF04433.17 EAX99287.1 - 0.058 13.7 2.9 1.3 9.4 2.9 2.5 1 1 0 1 1 1 0 SWIRM domain Ank_5 PF13857.6 EAX99288.1 - 7.5e-63 207.8 11.4 1.8e-13 50.4 0.1 5.2 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX99288.1 - 7e-56 184.4 2.6 2.7e-07 30.7 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.7 EAX99288.1 - 2.9e-49 165.6 7.5 2.1e-17 63.5 0.2 5.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99288.1 - 1.4e-48 162.7 5.6 1e-06 29.2 0.0 7.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99288.1 - 6.1e-42 136.8 9.1 0.00012 22.2 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat DUF3447 PF11929.8 EAX99288.1 - 2.5e-16 59.4 4.4 2.5e-16 59.4 4.4 3.4 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAX99288.1 - 1.4e-05 25.3 0.1 1.4 9.2 0.0 4.1 1 1 4 5 5 5 4 N terminal of Calcineurin-like phosphoesterase AnkUBD PF18418.1 EAX99288.1 - 0.0044 17.1 0.0 46 4.2 0.0 4.6 1 1 4 5 5 5 0 Ankyrin ubiquitin-binding domain DUF5023 PF16426.5 EAX99288.1 - 0.012 15.3 3.9 7.2 6.2 0.1 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF5023) DnaJ_C PF01556.18 EAX99290.1 - 5.3e-24 85.0 0.0 8.4e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAX99290.1 - 1.4e-20 73.2 5.1 2.4e-20 72.4 5.1 1.4 1 0 0 1 1 1 1 DnaJ domain E2F_TDP PF02319.20 EAX99290.1 - 0.039 14.0 0.8 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 EAX99292.1 - 1.9e-50 171.7 0.0 2.3e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99292.1 - 5.1e-34 117.7 0.0 6.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX99292.1 - 4.4e-05 22.9 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAX99292.1 - 0.00011 21.3 0.8 0.00016 20.8 0.8 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAX99292.1 - 0.0039 16.0 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EAX99292.1 - 0.021 14.2 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 EAX99292.1 - 0.029 13.4 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EAX99292.1 - 0.036 13.6 0.2 0.24 11.0 0.1 2.1 1 1 0 2 2 2 0 RIO1 family DNA_pol_phi PF04931.13 EAX99292.1 - 0.063 11.4 0.0 0.098 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Homeobox_KN PF05920.11 EAX99293.1 - 4.9e-11 42.3 1.2 9.4e-11 41.4 1.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAX99293.1 - 5.8e-08 32.5 1.5 8.9e-08 31.9 1.5 1.3 1 0 0 1 1 1 1 Homeodomain AAA_5 PF07728.14 EAX99296.1 - 8.8e-05 22.5 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EAX99296.1 - 0.00017 20.7 0.2 0.00024 20.3 0.1 1.3 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 EAX99296.1 - 0.0009 19.7 0.0 0.0011 19.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 EAX99296.1 - 0.002 17.2 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DAP3 PF10236.9 EAX99296.1 - 0.0042 16.3 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 EAX99296.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EAX99296.1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAX99296.1 - 0.022 15.1 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EAX99296.1 - 0.028 14.5 0.2 0.1 12.7 0.0 1.7 1 1 1 2 2 2 0 Helicase HerA, central domain DUF1319 PF07028.11 EAX99296.1 - 0.028 14.6 0.1 0.04 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF853 PF05872.12 EAX99296.1 - 0.036 12.7 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_7 PF12775.7 EAX99296.1 - 0.037 13.5 0.2 0.056 12.9 0.2 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EAX99296.1 - 0.047 13.7 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAX99296.1 - 0.062 13.7 0.1 0.28 11.6 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Microtub_bd PF16796.5 EAX99296.1 - 0.094 12.6 0.2 0.13 12.1 0.2 1.4 1 1 0 1 1 1 0 Microtubule binding CbiA PF01656.23 EAX99296.1 - 0.14 12.2 0.5 0.51 10.4 0.5 1.7 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EAX99296.1 - 0.18 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3839 PF12943.7 EAX99297.1 - 2.7e-157 521.5 12.9 3.3e-157 521.1 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX99297.1 - 0.04 14.3 0.5 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX99297.1 - 0.39 11.2 6.5 2.2 8.8 0.9 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRD PF00874.20 EAX99297.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.3 5 0 0 5 5 5 0 PRD domain Tup_N PF08581.10 EAX99297.1 - 0.52 10.6 5.0 9.7 6.6 0.0 3.8 4 0 0 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX99299.1 - 3.1e-06 26.8 3.0 3.1e-06 26.8 3.0 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99299.1 - 7.8e-06 26.2 0.4 6.2e-05 23.3 0.4 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99299.1 - 4.6e-05 23.2 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAX99299.1 - 5.3e-05 23.1 0.2 0.00027 20.7 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAX99299.1 - 7.3e-05 22.8 4.2 0.00015 21.8 3.9 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EAX99299.1 - 0.00051 19.7 0.7 0.0031 17.2 0.3 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX99299.1 - 0.0014 18.5 0.9 0.003 17.4 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX99299.1 - 0.0048 17.2 0.0 0.014 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAX99299.1 - 0.018 15.5 0.1 0.52 10.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAX99299.1 - 0.06 12.9 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX99299.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX99299.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX99299.1 - 0.32 11.2 3.9 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAX99300.1 - 2.2 8.2 5.0 4.2 7.3 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX99301.1 - 1.3e-62 210.0 5.8 1.4e-62 209.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AcMNPV_Ac109 PF05054.12 EAX99301.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Pox_D5 PF03288.16 EAX99302.1 - 0.00017 22.0 2.8 0.00087 19.7 2.8 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX99302.1 - 0.029 15.0 0.2 0.061 14.0 0.2 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF4049 PF13258.6 EAX99302.1 - 0.039 13.0 1.1 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Ank_2 PF12796.7 EAX99303.1 - 3.9e-36 123.5 5.9 3e-15 56.6 0.2 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99303.1 - 3.6e-31 103.7 0.8 8.8e-05 22.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAX99303.1 - 6.5e-29 99.9 2.5 3.9e-09 36.9 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99303.1 - 2.4e-27 94.2 6.0 7.7e-06 26.1 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAX99303.1 - 2.2e-25 88.4 0.0 2.2e-09 37.4 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) BACK PF07707.15 EAX99303.1 - 0.00049 20.2 1.4 0.0015 18.6 1.4 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF810 PF05664.11 EAX99304.1 - 0.022 13.3 0.0 0.041 12.4 0.0 1.5 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Ank_2 PF12796.7 EAX99305.1 - 4.5e-22 78.4 0.4 4.4e-14 52.8 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99305.1 - 5.2e-13 49.2 0.6 4.3e-05 24.0 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99305.1 - 1.3e-09 37.4 0.0 1.2e-06 28.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAX99305.1 - 1.4e-08 34.8 0.3 0.002 18.4 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99305.1 - 5.9e-07 29.7 0.1 0.00015 22.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat TcdB_N PF12918.7 EAX99305.1 - 0.002 18.4 4.8 0.0077 16.5 4.8 2.1 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain DUF2570 PF10828.8 EAX99305.1 - 0.022 14.6 1.4 0.039 13.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TACC_C PF05010.14 EAX99305.1 - 0.024 14.5 1.2 0.044 13.6 1.2 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Yuri_gagarin PF15934.5 EAX99305.1 - 0.037 13.9 0.7 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Yuri gagarin Poty_coat PF00767.18 EAX99305.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Potyvirus coat protein LRR_5 PF13306.6 EAX99306.1 - 4.5e-06 26.7 5.9 5.5e-06 26.4 5.9 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) TPR_2 PF07719.17 EAX99307.1 - 4e-06 26.5 0.3 1.6 9.1 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX99307.1 - 1e-05 25.6 8.1 0.4 10.9 0.0 4.9 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAX99307.1 - 6.2e-05 23.2 4.9 0.045 14.0 0.0 4.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAX99307.1 - 0.00053 19.7 0.2 3.9 7.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAX99307.1 - 0.0011 19.5 0.9 5.9 7.8 0.1 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat Ank_4 PF13637.6 EAX99308.1 - 7.3e-15 55.1 0.3 8e-07 29.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99308.1 - 1.1e-12 48.4 0.3 2.6e-07 31.1 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99308.1 - 2.5e-12 46.7 0.5 2.4e-07 30.9 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX99308.1 - 6.2e-09 36.0 0.1 9e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99308.1 - 2.8e-08 33.4 0.1 0.003 17.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Pox_Ag35 PF03286.14 EAX99309.1 - 0.13 12.0 5.4 0.21 11.4 5.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mito_fiss_reg PF05308.11 EAX99312.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAX99312.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1493 PF07377.12 EAX99314.1 - 0.041 14.3 0.7 0.088 13.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99315.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99316.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX99318.1 - 6.4e-08 33.1 0.0 0.00092 19.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99318.1 - 2.8e-07 30.3 0.1 4.3 8.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAX99318.1 - 3.9e-06 27.3 0.0 0.0016 18.9 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99318.1 - 7.7e-06 26.1 0.1 0.58 10.7 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX99318.1 - 2.6e-05 24.4 0.0 0.033 14.5 0.0 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) CDC37_C PF08564.10 EAX99319.1 - 0.005 16.9 8.9 0.74 10.0 0.2 2.7 2 0 0 2 2 2 2 Cdc37 C terminal domain DUF3987 PF13148.6 EAX99319.1 - 2.2 7.2 4.6 3.8 6.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) VHS PF00790.19 EAX99320.1 - 0.072 12.9 4.5 0.5 10.2 0.3 3.1 3 0 0 3 3 3 0 VHS domain Proteasome PF00227.26 EAX99321.1 - 2.6e-36 124.9 0.0 2.9e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sugar_tr PF00083.24 EAX99322.1 - 2.2e-53 181.7 34.1 1.9e-29 102.9 17.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAX99322.1 - 1.5e-24 86.6 28.6 1.5e-24 86.6 28.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAX99322.1 - 0.0056 15.3 8.2 0.0056 15.3 8.2 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein Ank_2 PF12796.7 EAX99323.1 - 1e-41 141.4 17.4 5.1e-13 49.4 1.2 4.9 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99323.1 - 3.6e-41 139.0 9.0 1.4e-10 41.4 0.1 7.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99323.1 - 1.9e-39 133.5 5.0 1.9e-39 133.5 5.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX99323.1 - 3.2e-39 131.7 5.2 1.6e-07 31.5 0.1 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAX99323.1 - 6.1e-27 90.7 12.8 0.0012 19.2 0.1 9.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EAX99323.1 - 1.7e-23 82.3 11.5 1.5e-06 28.4 0.2 5.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) RL PF17797.1 EAX99323.1 - 7 6.7 11.9 13 5.8 0.1 5.2 5 0 0 5 5 5 0 RL domain tRNA-synt_2 PF00152.20 EAX99324.1 - 2.6e-73 246.9 0.0 3.6e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAX99324.1 - 1.6e-08 34.4 0.0 4.9e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAX99324.1 - 5e-06 26.2 0.0 0.0072 15.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pedibin PF08182.11 EAX99324.1 - 0.039 13.7 3.5 0.12 12.2 3.5 1.8 1 0 0 1 1 1 0 Pedibin/Hym-346 family KilA-N PF04383.13 EAX99326.1 - 2.3e-41 140.1 0.3 6e-41 138.8 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Acyl_transf_2 PF02273.15 EAX99326.1 - 0.0094 15.2 0.2 0.035 13.3 0.1 1.8 1 1 1 2 2 2 1 Acyl transferase DUF3213 PF11491.8 EAX99326.1 - 0.014 15.5 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAX99326.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pkinase_Tyr PF07714.17 EAX99327.1 - 1.7e-20 73.4 1.1 1.2e-15 57.5 0.0 3.6 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 EAX99327.1 - 1.3e-17 64.1 0.5 2.3e-16 59.9 0.1 3.1 2 1 0 3 3 3 1 Protein kinase domain HORMA PF02301.18 EAX99327.1 - 0.018 14.7 0.9 0.12 12.0 0.4 2.4 2 0 0 2 2 2 0 HORMA domain RICTOR_V PF14668.6 EAX99327.1 - 0.06 13.6 0.8 0.46 10.8 0.1 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HycH PF07450.11 EAX99327.1 - 0.071 13.5 3.3 10 6.5 0.0 4.1 3 0 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH HSP70 PF00012.20 EAX99329.1 - 1.9e-47 161.8 2.1 1.9e-47 161.8 2.1 1.4 1 1 0 1 1 1 1 Hsp70 protein CREPT PF16566.5 EAX99329.1 - 0.035 14.3 0.7 0.1 12.7 0.7 1.9 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PI3K_P85_iSH2 PF16454.5 EAX99329.1 - 0.039 13.5 3.3 0.12 12.0 3.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PMC2NT PF08066.12 EAX99329.1 - 0.21 12.3 2.1 0.63 10.8 0.6 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain FtsA PF14450.6 EAX99329.1 - 1.7 9.1 4.3 11 6.5 0.1 3.1 3 2 0 3 3 3 0 Cell division protein FtsA DUF3447 PF11929.8 EAX99330.1 - 5.9e-28 96.6 7.1 5.9e-28 96.6 7.1 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99330.1 - 1.9e-07 31.6 0.7 0.00027 21.5 0.0 3.5 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99330.1 - 2.6e-06 27.9 1.2 0.00045 20.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99330.1 - 0.004 17.6 0.6 4.7 7.8 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EAX99330.1 - 0.0049 17.2 0.1 1.2 9.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99330.1 - 0.034 14.7 5.5 42 5.2 0.0 5.3 5 0 0 5 5 5 0 Ankyrin repeat EF-hand_12 PF17901.1 EAX99330.1 - 0.08 13.4 3.9 0.099 13.1 0.7 2.7 1 1 1 2 2 2 0 EF-hand fold domain LRR_5 PF13306.6 EAX99331.1 - 8.3e-14 51.7 0.1 1.5e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99331.1 - 0.00039 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_5 PF13306.6 EAX99332.1 - 2.8e-06 27.3 6.6 5.6e-05 23.1 0.2 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LPP PF04728.13 EAX99334.1 - 0.2 12.1 0.3 0.2 12.1 0.3 4.0 4 1 0 4 4 4 0 Lipoprotein leucine-zipper ArAE_2 PF10334.9 EAX99334.1 - 1 9.2 8.8 0.084 12.7 1.8 2.7 2 1 1 3 3 3 0 Aromatic acid exporter family member 2 ApoO PF09769.9 EAX99334.1 - 6.4 6.8 10.3 12 5.9 0.3 3.2 2 2 1 3 3 3 0 Apolipoprotein O Metallophos PF00149.28 EAX99335.1 - 3.5e-32 112.6 0.3 5.1e-32 112.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX99335.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EAX99335.1 - 0.0018 18.7 0.3 0.0038 17.6 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Gly_rich PF12810.7 EAX99336.1 - 1.5e-49 169.1 31.9 1.8e-49 168.8 31.9 1.1 1 0 0 1 1 1 1 Glycine rich protein DnaJ PF00226.31 EAX99337.1 - 1.2e-08 34.9 0.1 2.3e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2929 PF11151.8 EAX99337.1 - 0.052 13.8 1.0 0.15 12.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) HyaE PF07449.11 EAX99337.1 - 0.11 12.5 0.0 0.99 9.4 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 EAX99337.1 - 0.13 12.2 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF872 PF05915.12 EAX99338.1 - 5.5e-08 33.0 0.1 6.2e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) KxDL PF10241.9 EAX99339.1 - 0.00013 22.1 2.8 0.00013 22.1 2.8 6.6 3 2 3 7 7 7 1 Uncharacterized conserved protein AAA_13 PF13166.6 EAX99339.1 - 0.00085 18.1 26.9 0.00085 18.1 26.9 2.9 1 1 2 3 3 2 1 AAA domain GAS PF13851.6 EAX99339.1 - 0.0046 16.3 63.8 0.0053 16.1 26.8 3.8 2 2 1 4 4 4 2 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 EAX99339.1 - 0.0058 16.8 2.4 0.0058 16.8 2.4 5.6 3 2 3 6 6 6 2 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.6 EAX99339.1 - 0.011 15.4 8.4 0.011 15.4 8.4 5.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 EAX99339.1 - 0.015 15.7 4.2 0.015 15.7 4.2 5.6 2 2 2 4 4 3 0 Nucleopolyhedrovirus P10 protein DNA_photolyase PF00875.18 EAX99339.1 - 0.017 15.2 1.2 0.091 12.8 0.1 2.7 2 0 0 2 2 2 0 DNA photolyase Peptidase_U32_C PF16325.5 EAX99339.1 - 0.033 14.5 0.6 0.033 14.5 0.6 3.4 3 1 0 3 3 3 0 Peptidase family U32 C-terminal domain CLZ PF16526.5 EAX99339.1 - 0.063 13.6 1.0 0.063 13.6 1.0 6.2 1 1 3 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Filament PF00038.21 EAX99339.1 - 0.23 11.0 57.6 2.1 7.9 11.5 3.4 1 1 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 EAX99339.1 - 0.55 7.7 50.3 0.12 9.8 35.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EAX99339.1 - 3.8 7.6 42.7 0.43 10.6 5.0 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EAX99339.1 - 6.9 6.3 68.5 2.1 8.0 26.0 5.0 1 1 0 3 3 3 0 SWI5-dependent HO expression protein 3 Tctex-1 PF03645.13 EAX99340.1 - 3.2e-30 104.4 0.3 3.6e-30 104.2 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 EAX99340.1 - 0.0047 16.6 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL4 family MatE PF01554.18 EAX99341.1 - 3e-27 95.3 28.7 1.7e-15 57.1 11.5 2.5 2 1 0 2 2 2 2 MatE Ank_4 PF13637.6 EAX99342.1 - 8.7e-16 58.1 0.9 7.8e-12 45.5 0.0 4.0 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99342.1 - 3e-15 56.6 0.9 5.3e-10 39.7 0.1 3.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99342.1 - 2.4e-14 53.2 0.1 4.3e-11 42.8 0.1 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99342.1 - 6.5e-14 50.7 0.1 3.2e-05 24.0 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAX99342.1 - 3.6e-08 33.5 0.0 3.5e-06 27.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Myb_DNA-binding PF00249.31 EAX99343.1 - 5.3e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 EAX99343.1 - 0.0019 18.3 0.0 0.0057 16.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain vWF_A PF12450.8 EAX99343.1 - 0.043 13.7 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 von Willebrand factor RXT2_N PF08595.11 EAX99343.1 - 2 8.5 13.1 6.2 6.8 4.9 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EAX99343.1 - 2.8 8.4 11.3 3.3 8.1 0.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1104 PF06518.11 EAX99343.1 - 4.2 7.8 11.1 0.34 11.3 3.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Ank_2 PF12796.7 EAX99344.1 - 3.3e-16 59.6 4.7 1.7e-07 31.7 0.2 4.5 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99344.1 - 1.3e-10 41.3 0.0 0.002 18.4 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99344.1 - 2.4e-08 34.3 2.2 0.64 10.7 0.1 6.2 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99344.1 - 2.4e-08 33.6 7.1 0.067 13.8 0.1 6.5 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 EAX99344.1 - 0.039 14.4 1.2 27 5.4 0.2 4.6 4 1 0 4 4 4 0 Ankyrin repeat zf-MYND PF01753.18 EAX99345.1 - 0.012 15.7 7.5 0.02 14.9 7.5 1.3 1 0 0 1 1 1 0 MYND finger PCC_BT PF18140.1 EAX99345.1 - 0.17 12.3 0.0 0.53 10.6 0.0 1.7 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain SLATT_4 PF18186.1 EAX99346.1 - 0.013 15.1 0.2 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF2225 PF09986.9 EAX99346.1 - 0.068 12.9 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) EHN PF06441.12 EAX99348.1 - 0.14 12.5 0.8 0.59 10.5 0.0 2.5 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Bromodomain PF00439.25 EAX99349.1 - 9e-24 83.4 0.1 1.2e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Bromodomain Staphopain_pro PF14731.6 EAX99350.1 - 0.00088 19.3 1.8 0.0011 19.0 1.8 1.1 1 0 0 1 1 1 1 Staphopain proregion Ins_P5_2-kin PF06090.12 EAX99350.1 - 0.051 13.0 0.1 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Amidase02_C PF12123.8 EAX99352.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase KilA-N PF04383.13 EAX99353.1 - 8.1e-27 93.3 0.1 1.2e-26 92.7 0.0 1.3 2 0 0 2 2 2 1 KilA-N domain zf-RING_9 PF13901.6 EAX99353.1 - 0.13 12.2 0.3 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAX99354.1 - 6.8e-145 480.8 9.2 8.4e-145 480.5 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAX99355.1 - 4.5e-09 36.2 0.3 4.5e-09 36.2 0.3 7.1 5 1 1 6 6 6 1 Phage tail repeat like DUF4795 PF16043.5 EAX99355.1 - 0.014 15.0 27.7 0.27 10.8 1.7 4.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) Topo_Zn_Ribbon PF08272.11 EAX99355.1 - 0.14 11.9 12.1 11 5.8 0.2 5.2 2 1 4 6 6 6 0 Topoisomerase I zinc-ribbon-like HEPN-like_int PF18867.1 EAX99355.1 - 1.1 9.1 5.1 15 5.5 0.3 3.2 2 1 2 4 4 4 0 HEPN-like integron domain YmaF PF12788.7 EAX99355.1 - 6.4 7.4 7.9 43 4.7 0.1 3.2 2 1 0 2 2 2 0 YmaF family DUF1493 PF07377.12 EAX99356.1 - 0.037 14.5 0.6 0.077 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99357.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99358.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DNA_pol_B_2 PF03175.13 EAX99359.1 - 2.1e-22 79.6 5.1 2.4e-22 79.5 5.1 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Pox_A32 PF04665.12 EAX99360.1 - 3.8e-08 33.1 0.2 5.3e-08 32.6 0.1 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein GRDP-like PF07173.12 EAX99360.1 - 0.47 11.1 4.0 2.8 8.6 1.4 2.7 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like DUF4107 PF13389.6 EAX99363.1 - 2e-49 167.9 1.0 2.3e-49 167.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2890 PF11081.8 EAX99364.1 - 0.13 12.4 0.1 0.15 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4107 PF13389.6 EAX99365.1 - 3e-58 196.6 11.1 7.7e-39 133.5 4.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99365.1 - 0.11 12.9 0.6 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAX99366.1 - 5.8e-153 507.2 13.8 7.3e-153 506.9 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99366.1 - 0.091 13.2 2.5 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX99366.1 - 0.34 11.2 3.6 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal T5orf172 PF10544.9 EAX99367.1 - 5.4e-05 23.7 0.1 0.00013 22.4 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAX99367.1 - 0.0056 16.5 0.3 0.036 13.9 0.1 2.1 2 0 0 2 2 2 1 KilA-N domain Lectin_legB PF00139.19 EAX99367.1 - 0.017 14.6 0.8 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Legume lectin domain LRR_6 PF13516.6 EAX99368.1 - 0.0011 18.8 13.2 0.0016 18.3 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich repeat COPI_C PF06957.11 EAX99369.1 - 3.5e-62 210.4 0.1 6.7e-62 209.5 0.1 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 EAX99369.1 - 2.9e-46 158.4 15.8 7.8e-45 153.7 6.9 3.1 2 1 0 3 3 3 2 Coatomer WD associated region WD40 PF00400.32 EAX99369.1 - 9.5e-12 45.3 13.3 0.00099 19.9 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX99369.1 - 5.1e-11 42.7 0.4 0.058 13.7 0.0 6.2 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain DUF2119 PF09892.9 EAX99369.1 - 0.0013 18.2 0.4 0.0033 16.8 0.4 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2119) BUD22 PF09073.10 EAX99371.1 - 1.4 8.2 13.0 1.7 7.9 13.0 1.1 1 0 0 1 1 1 0 BUD22 TPR_1 PF00515.28 EAX99372.1 - 4.3e-08 32.6 5.6 7.8e-05 22.3 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAX99372.1 - 1.5e-07 31.3 0.1 0.072 13.5 0.0 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAX99372.1 - 2.3e-07 30.4 0.1 0.012 15.2 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 EAX99372.1 - 2.3e-06 27.3 3.0 0.00019 21.3 0.0 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAX99372.1 - 3.8e-06 26.7 5.1 0.0013 18.8 0.0 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAX99372.1 - 8.2e-05 22.8 0.0 0.018 15.3 0.0 2.7 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAX99372.1 - 0.0024 18.4 1.4 0.14 12.7 0.1 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAX99372.1 - 0.0055 17.4 0.2 1.2 10.1 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAX99372.1 - 0.015 15.5 0.0 0.051 13.7 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAX99372.1 - 0.081 13.2 1.3 0.28 11.4 0.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EAX99372.1 - 0.094 13.0 0.5 0.87 10.0 0.1 2.6 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 EAX99372.1 - 0.12 13.0 0.4 12 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAX99372.1 - 0.18 12.4 0.0 2.3 9.0 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DNase_II PF03265.15 EAX99374.1 - 3.6e-87 292.7 3.7 4e-87 292.5 3.7 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II WASH_WAHD PF11945.8 EAX99374.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex Ank_4 PF13637.6 EAX99375.1 - 6.9e-23 80.7 7.2 0.00028 21.4 0.0 8.3 5 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99375.1 - 8.1e-22 77.6 4.9 3.6e-09 37.1 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99375.1 - 8.9e-13 47.2 13.5 0.25 12.0 0.0 10.2 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 EAX99375.1 - 5.7e-10 39.2 3.8 0.31 11.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX99375.1 - 1.3e-09 38.1 9.4 0.015 15.6 1.4 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99376.1 - 2.3e-22 79.4 2.8 1.2e-06 29.0 0.0 4.9 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99376.1 - 4.1e-18 65.5 2.9 2.4e-05 24.8 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99376.1 - 7.4e-16 56.7 5.7 0.14 12.8 0.0 8.6 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EAX99376.1 - 1.5e-13 50.5 0.4 0.46 11.0 0.1 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX99376.1 - 1.8e-12 47.2 0.4 0.0042 17.4 0.0 5.7 4 2 1 5 5 5 2 Ankyrin repeats (many copies) DUF655 PF04919.12 EAX99376.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF655) Ank_4 PF13637.6 EAX99377.1 - 1.2e-19 70.4 1.2 2.1e-05 25.0 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99377.1 - 2.8e-17 63.1 0.6 1.5e-11 44.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99377.1 - 2.1e-11 43.9 0.1 0.025 14.9 0.1 4.3 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99377.1 - 1.4e-09 37.3 6.5 0.062 13.9 0.0 5.6 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EAX99377.1 - 8.2e-09 35.5 1.5 0.073 13.6 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EAX99378.1 - 1.2e-27 96.3 7.4 1.2e-07 32.2 0.0 6.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99378.1 - 9.4e-21 73.9 7.1 5.9e-06 26.7 0.0 7.5 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99378.1 - 4.9e-19 66.4 11.8 0.23 12.1 0.0 11.1 12 1 1 13 13 13 6 Ankyrin repeat Ank PF00023.30 EAX99378.1 - 4.3e-13 49.1 5.9 0.54 10.8 0.0 9.1 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 EAX99378.1 - 1.4e-11 44.4 5.6 0.017 15.5 0.0 7.4 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Big_7 PF17957.1 EAX99379.1 - 1.2e-08 35.6 25.3 0.0015 19.3 0.2 6.8 6 1 1 7 7 7 2 Bacterial Ig domain Alph_Pro_TM PF09608.10 EAX99379.1 - 0.0014 18.5 0.0 4.3 7.1 0.0 3.8 4 0 0 4 4 4 1 Putative transmembrane protein (Alph_Pro_TM) DUF4625 PF15418.6 EAX99379.1 - 0.03 14.6 0.6 0.03 14.6 0.6 6.4 4 1 2 8 8 8 0 Domain of unknown function (DUF4625) Porphobil_deamC PF03900.15 EAX99379.1 - 0.13 12.7 0.2 12 6.4 0.0 3.8 5 0 0 5 5 5 0 Porphobilinogen deaminase, C-terminal domain CBM_3 PF00942.18 EAX99379.1 - 1.4 9.4 17.2 0.19 12.2 0.6 4.7 5 0 0 5 5 5 0 Cellulose binding domain DUF2326 PF10088.9 EAX99379.1 - 1.9 8.2 11.6 6.4 6.5 0.0 4.6 3 1 3 6 6 6 0 Uncharacterised protein conserved in bacteria (DUF2326) HCBP_related PF06594.11 EAX99379.1 - 3.4 7.7 6.8 4.4 7.3 0.1 4.0 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Ank_4 PF13637.6 EAX99380.1 - 1e-22 80.2 12.1 4.7e-05 23.9 0.0 8.5 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99380.1 - 4.6e-19 68.8 14.6 1.2e-08 35.4 0.1 5.8 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99380.1 - 2e-15 55.3 13.5 0.34 11.6 0.0 9.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAX99380.1 - 1.3e-14 54.1 2.7 0.0015 18.8 0.0 6.3 4 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99380.1 - 1.8e-09 37.6 7.4 0.27 11.7 0.0 7.3 6 1 1 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EAX99381.1 - 1.7e-14 54.0 0.4 0.0004 20.9 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99381.1 - 3e-14 53.4 1.8 1.1e-08 35.5 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99381.1 - 6.3e-09 35.4 2.1 2.4 9.0 0.0 6.0 5 1 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAX99381.1 - 1.8e-08 34.5 0.7 0.098 13.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX99381.1 - 1.7e-07 31.4 0.3 0.057 13.7 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) GAT PF03127.14 EAX99381.1 - 0.024 14.9 0.2 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 GAT domain Mo25 PF08569.11 EAX99381.1 - 0.054 12.9 0.4 0.068 12.5 0.4 1.2 1 0 0 1 1 1 0 Mo25-like FliJ PF02050.16 EAX99382.1 - 0.022 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAX99383.1 - 8.7e-74 247.1 4.4 1e-73 246.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX99383.1 - 0.14 10.6 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Trypan_PARP PF05887.11 EAX99384.1 - 0.054 13.5 8.5 0.084 12.9 8.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAX99384.1 - 3.5 8.1 5.6 5 7.6 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DDR PF08841.10 EAX99385.1 - 0.099 11.6 0.2 0.095 11.7 0.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GPS2_interact PF15784.5 EAX99385.1 - 0.31 11.5 3.2 0.37 11.2 3.2 1.3 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Collagen_bind_2 PF12904.7 EAX99386.1 - 0.12 12.3 0.0 4.4 7.4 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase MULE PF10551.9 EAX99387.1 - 1.8e-10 41.1 1.5 3.2e-10 40.3 1.5 1.4 1 0 0 1 1 1 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX99387.1 - 0.0027 17.8 2.2 0.0096 16.0 2.2 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX99387.1 - 0.0031 16.5 0.3 0.0047 15.8 0.3 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Ras PF00071.22 EAX99391.1 - 5.8e-38 130.0 0.2 7.1e-38 129.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99391.1 - 4.5e-29 101.1 0.0 6.4e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99391.1 - 1.2e-10 41.2 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAX99391.1 - 7.4e-08 32.0 0.0 1.3e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX99391.1 - 5.4e-06 26.4 0.1 0.089 12.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX99391.1 - 1.2e-05 24.9 0.0 0.00021 20.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 EAX99391.1 - 6.3e-05 22.4 0.0 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAX99391.1 - 8.8e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAX99391.1 - 0.00014 21.6 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX99391.1 - 0.00073 19.1 0.1 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAX99391.1 - 0.0076 16.5 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAX99391.1 - 0.017 15.5 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAX99391.1 - 0.024 14.5 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 EAX99391.1 - 0.05 12.9 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Sigma54_activat PF00158.26 EAX99391.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 EAX99391.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein GA-like PF17573.2 EAX99391.1 - 0.087 12.8 1.5 0.54 10.2 1.5 2.1 1 1 0 1 1 1 0 GA-like domain AAA_24 PF13479.6 EAX99391.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DoxA PF07680.11 EAX99391.1 - 0.13 12.1 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 TQO small subunit DoxA TniB PF05621.11 EAX99391.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 EAX99391.1 - 0.18 11.4 0.1 8 6.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRIMA1 PF16101.5 EAX99392.1 - 0.0046 17.0 1.3 0.0088 16.1 1.3 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 LRR_5 PF13306.6 EAX99394.1 - 1.9e-17 63.4 2.8 1.9e-17 63.4 0.7 1.8 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99394.1 - 0.0015 18.3 0.0 0.032 14.0 0.0 2.1 1 1 1 2 2 2 1 Leucine rich repeat LRR_5 PF13306.6 EAX99395.1 - 7.7e-59 197.2 15.9 1.2e-22 80.2 1.0 3.5 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99395.1 - 5.4e-08 32.5 1.2 1.7 8.5 0.0 6.9 4 2 4 8 8 8 2 Leucine rich repeat LRR_4 PF12799.7 EAX99395.1 - 0.0078 16.6 5.4 41 4.8 0.0 6.4 5 3 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX99395.1 - 0.59 10.9 2.9 26 5.9 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Sa_NUDIX PF18167.1 EAX99396.1 - 3.4 7.4 70.0 22 4.8 16.9 4.3 1 1 2 3 3 3 0 SMODS-associated NUDIX domain RRM_1 PF00076.22 EAX99397.1 - 6.7e-32 109.1 0.6 6.1e-13 48.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAX99397.1 - 4.5e-11 42.5 0.6 0.008 16.0 0.0 3.2 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EAX99397.1 - 7.5e-11 41.7 0.4 0.0035 16.9 0.0 3.2 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAX99397.1 - 0.0021 18.0 0.1 2.4 8.2 0.0 3.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAX99397.1 - 0.0066 16.5 2.3 0.0076 16.3 0.3 2.1 2 0 0 2 2 2 1 RNA binding motif SieB PF14163.6 EAX99397.1 - 0.0089 15.5 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Super-infection exclusion protein B RNA_bind PF08675.11 EAX99397.1 - 0.0093 16.0 0.1 0.45 10.6 0.0 2.8 3 1 0 3 3 3 1 RNA binding domain YflT PF11181.8 EAX99397.1 - 0.068 13.7 0.9 7.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 EAX99397.1 - 0.15 12.2 0.1 6.6 6.9 0.0 2.9 4 0 0 4 4 4 0 Limkain b1 F_bP_aldolase PF01116.20 EAX99398.1 - 1.9e-92 309.7 0.0 2.4e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II F_bP_aldolase PF01116.20 EAX99399.1 - 1.9e-92 309.7 0.0 2.4e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pkinase PF00069.25 EAX99401.1 - 1.9e-54 184.8 0.0 2.6e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99401.1 - 1.8e-28 99.5 0.0 2.5e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99401.1 - 1.9e-10 40.5 0.0 3.9e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAX99401.1 - 0.011 14.8 1.0 0.065 12.3 0.1 2.3 2 1 1 3 3 3 0 Seadornavirus VP7 Kdo PF06293.14 EAX99401.1 - 0.085 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1143 PF06608.11 EAX99402.1 - 0.018 15.1 1.3 0.03 14.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1143) MciZ PF13072.6 EAX99402.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Pkinase PF00069.25 EAX99403.1 - 5.6e-51 173.4 0.1 6.8e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99403.1 - 1.3e-26 93.4 0.0 1.7e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99403.1 - 2.3e-07 30.4 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ubiquitin PF00240.23 EAX99404.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 EAX99406.1 - 2.2e-53 181.3 0.0 3.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99406.1 - 3.4e-29 101.9 0.0 4.2e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99406.1 - 6.9e-08 32.2 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like MIT_C PF16565.5 EAX99406.1 - 0.0017 18.3 0.1 0.0049 16.9 0.1 1.8 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT Kdo PF06293.14 EAX99406.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1996 PF09362.10 EAX99406.1 - 0.14 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1996) TPR_1 PF00515.28 EAX99407.1 - 0.0012 18.5 0.1 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAX99407.1 - 0.0024 17.9 0.1 3.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Aurora-A_bind PF09041.10 EAX99407.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Aurora-A binding CBM_11 PF03425.13 EAX99407.1 - 0.1 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) F_bP_aldolase PF01116.20 EAX99409.1 - 2.6e-92 309.3 0.0 3.3e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3839 PF12943.7 EAX99410.1 - 3.3e-156 517.9 15.8 4e-156 517.6 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX99410.1 - 0.12 13.0 5.7 0.3 11.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAX99410.1 - 0.19 11.6 1.3 0.5 10.2 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAX99410.1 - 0.33 11.4 7.4 2.1 8.8 1.0 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX99410.1 - 7.9 6.9 7.9 12 6.3 0.2 3.9 3 2 1 4 4 4 0 Tup N-terminal Pox_A32 PF04665.12 EAX99411.1 - 3.1e-07 30.1 2.4 3.1e-07 30.1 2.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX99411.1 - 4.5e-05 23.2 0.2 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX99411.1 - 5.8e-05 23.4 0.1 0.00039 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX99411.1 - 8.8e-05 22.6 2.9 0.0002 21.4 3.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99411.1 - 0.0006 19.6 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX99411.1 - 0.0017 18.0 0.5 0.0098 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EAX99411.1 - 0.0023 17.7 0.6 0.0043 16.9 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAX99411.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX99411.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX99411.1 - 0.097 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX99411.1 - 0.14 12.6 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX99411.1 - 0.51 10.6 3.4 11 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAX99413.1 - 1.2e-63 213.3 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) T5orf172 PF10544.9 EAX99414.1 - 1.1e-07 32.4 0.5 6.4e-07 29.9 0.4 2.2 2 1 0 2 2 2 1 T5orf172 domain Lectin_legB PF00139.19 EAX99414.1 - 0.012 15.2 0.4 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain KilA-N PF04383.13 EAX99415.1 - 1.3e-42 144.1 1.0 2.2e-42 143.4 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX99415.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) RRP36 PF06102.12 EAX99415.1 - 4.1 7.3 14.0 0.54 10.2 4.8 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Pox_A32 PF04665.12 EAX99416.1 - 5.5e-07 29.3 2.3 5.5e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99416.1 - 2.6e-05 24.5 0.2 0.00017 21.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99416.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99416.1 - 0.00012 22.2 3.5 0.00024 21.1 3.5 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99416.1 - 0.00051 19.9 0.1 0.00095 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX99416.1 - 0.0017 18.2 1.1 0.0035 17.2 1.1 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX99416.1 - 0.0021 17.7 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99416.1 - 0.008 16.5 0.0 0.016 15.6 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAX99416.1 - 0.071 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX99416.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX99416.1 - 0.083 13.3 0.1 0.67 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX99416.1 - 0.43 10.8 4.2 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Pox_D5 PF03288.16 EAX99418.1 - 2.2e-05 24.8 2.3 0.00011 22.6 2.3 2.1 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX99418.1 - 0.056 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain RRM_1 PF00076.22 EAX99419.1 - 1.7e-17 63.0 0.2 2.3e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAX99419.1 - 0.00087 19.4 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EAX99419.1 - 0.0031 17.5 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EAX99419.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAX99419.1 - 0.055 13.6 0.0 0.098 12.7 0.0 1.4 1 1 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 EAX99419.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Na_trans_assoc PF06512.13 EAX99420.1 - 0.083 13.2 0.0 0.083 13.2 0.0 6.5 3 2 2 6 6 6 0 Sodium ion transport-associated Ank_2 PF12796.7 EAX99421.1 - 1.2e-09 38.6 2.5 3.2e-06 27.6 0.3 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99421.1 - 5e-07 29.5 0.0 0.14 12.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX99421.1 - 1.4e-06 28.7 0.0 0.028 15.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99421.1 - 6.8e-06 26.3 0.4 0.096 13.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99421.1 - 0.011 15.7 4.2 0.056 13.4 0.8 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3447) CDtoxinA PF03498.14 EAX99421.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain APOBEC4_like PF18774.1 EAX99421.1 - 0.045 13.7 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase Ninjurin PF04923.12 EAX99421.1 - 0.077 12.9 0.0 7.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Ninjurin SCIMP PF15050.6 EAX99422.1 - 0.016 15.7 1.1 0.054 14.0 1.1 1.9 1 0 0 1 1 1 0 SCIMP protein Sigma_reg_N PF13800.6 EAX99422.1 - 0.14 12.5 2.4 0.19 12.0 0.3 2.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TRAM_LAG1_CLN8 PF03798.16 EAX99423.1 - 1.2e-23 83.9 21.8 1.9e-23 83.3 21.8 1.3 1 0 0 1 1 1 1 TLC domain Syja_N PF02383.18 EAX99424.1 - 6.8e-42 143.9 0.1 8.8e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Sld7_C PF18596.1 EAX99424.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Sld7 C-terminal domain CPSF_A PF03178.15 EAX99426.1 - 7.8e-11 41.8 0.1 1.8e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 CPSF A subunit region Sel1 PF08238.12 EAX99427.1 - 0.00028 21.4 3.7 0.026 15.2 0.8 3.4 4 0 0 4 4 4 1 Sel1 repeat CS PF04969.16 EAX99427.1 - 0.08 14.0 0.1 0.16 13.0 0.1 1.5 1 0 0 1 1 1 0 CS domain TPR_12 PF13424.6 EAX99427.1 - 0.089 13.1 0.2 0.3 11.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 EAX99428.1 - 1.1e-62 210.9 0.0 1.7e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAX99428.1 - 1.1e-19 69.8 5.7 2.5e-19 68.6 5.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAX99428.1 - 3.2e-07 30.2 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3447 PF11929.8 EAX99429.1 - 2.3e-14 53.1 0.1 2.3e-14 53.1 0.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) ATP13 PF12921.7 EAX99429.1 - 0.005 16.7 1.1 0.0092 15.8 0.8 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase expression PIF1 PF05970.14 EAX99429.1 - 0.47 9.6 2.1 0.7 9.0 0.7 1.7 1 1 1 2 2 2 0 PIF1-like helicase Ank_2 PF12796.7 EAX99430.1 - 2.2e-39 133.9 20.2 3e-15 56.6 3.0 4.3 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99430.1 - 1.5e-35 121.1 8.2 3.2e-09 37.2 0.1 5.5 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99430.1 - 2.2e-33 113.2 7.5 5.3e-08 33.0 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAX99430.1 - 5.6e-28 93.9 8.3 1.5e-06 28.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EAX99430.1 - 1.1e-19 70.2 4.8 4e-07 30.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99430.1 - 9.9e-17 60.7 4.5 9.9e-17 60.7 4.5 3.8 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAX99430.1 - 0.017 15.4 0.7 13 6.2 0.1 3.5 1 1 3 4 4 4 0 Pleckstrin homology domain Topo_Zn_Ribbon PF08272.11 EAX99430.1 - 0.14 11.8 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF3718 PF12514.8 EAX99430.1 - 0.72 10.1 8.2 22 5.3 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAX99431.1 - 9e-07 29.3 0.0 1.2e-06 28.9 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99431.1 - 1.2e-05 25.8 0.0 1.3e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99431.1 - 4.9e-05 23.6 0.0 7.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EAX99431.1 - 0.00034 20.8 0.0 0.00086 19.6 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAX99431.1 - 0.012 15.9 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sulfatase PF00884.23 EAX99432.1 - 1.4e-18 67.4 0.1 1.8e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EAX99432.1 - 7.6e-09 35.8 1.3 2.6e-08 34.1 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EAX99432.1 - 1.2e-06 28.3 0.2 3.1e-06 27.0 0.1 1.5 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EAX99432.1 - 0.0044 15.7 0.0 0.0056 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EAX99432.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily LRR_5 PF13306.6 EAX99434.1 - 4.2e-76 253.1 70.8 4.5e-19 68.7 12.5 7.4 3 3 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99434.1 - 2.5e-16 59.2 8.0 0.0048 16.6 0.2 8.6 9 0 0 9 9 9 4 Leucine rich repeat LRR_4 PF12799.7 EAX99434.1 - 3.5e-11 43.2 16.4 0.037 14.5 0.0 11.2 9 2 2 11 11 11 3 Leucine Rich repeats (2 copies) Tcp10_C PF07202.13 EAX99434.1 - 0.1 12.5 0.4 0.28 11.1 0.4 1.7 1 0 0 1 1 1 0 T-complex protein 10 C-terminus LRR_1 PF00560.33 EAX99434.1 - 9.3 7.2 9.2 14 6.7 0.1 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_5 PF13306.6 EAX99435.1 - 3.5e-23 82.0 20.9 1.8e-17 63.5 9.3 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99435.1 - 0.00011 21.9 0.1 0.25 11.1 0.0 3.5 2 2 2 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 EAX99436.1 - 1.1e-49 167.6 47.3 4.3e-25 88.1 11.3 4.7 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99436.1 - 4.8e-08 32.6 6.2 0.025 14.3 1.6 6.0 5 2 3 8 8 8 3 Leucine rich repeat LRR_4 PF12799.7 EAX99436.1 - 1e-05 25.7 12.1 2.7 8.5 0.1 6.2 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 EAX99436.1 - 0.0028 17.6 2.5 0.0065 16.4 2.5 1.7 1 0 0 1 1 1 1 TMEM154 protein family EVI2A PF05399.11 EAX99436.1 - 0.03 13.9 0.2 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Orf78 PF06024.12 EAX99436.1 - 0.034 14.5 0.2 0.065 13.5 0.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF4690 PF15756.5 EAX99436.1 - 0.09 13.4 0.5 0.21 12.2 0.5 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FAST_1 PF06743.15 EAX99437.1 - 0.00058 19.8 7.2 3.9 7.5 0.1 5.4 5 0 0 5 5 5 1 FAST kinase-like protein, subdomain 1 Dynein_AAA_lid PF17852.1 EAX99437.1 - 0.01 15.9 5.5 1.7 8.8 0.2 3.7 3 2 1 4 4 4 0 Dynein heavy chain AAA lid domain DnaA_N PF11638.8 EAX99437.1 - 0.025 14.3 0.1 0.084 12.6 0.1 1.9 1 0 0 1 1 1 0 DnaA N-terminal domain Imm49 PF15575.6 EAX99437.1 - 0.035 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 49 YmgB PF10798.8 EAX99437.1 - 0.11 12.3 4.7 0.49 10.3 0.3 3.1 2 1 0 2 2 2 0 Biofilm development protein YmgB/AriR Bcl-2 PF00452.19 EAX99437.1 - 0.34 11.6 1.5 5.4 7.8 0.0 3.4 4 1 1 5 5 5 0 Apoptosis regulator proteins, Bcl-2 family Clathrin PF00637.20 EAX99437.1 - 0.95 9.3 5.9 4.3 7.2 1.3 3.4 2 2 0 2 2 2 0 Region in Clathrin and VPS PSP PF04046.16 EAX99438.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99439.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAX99440.1 - 0.087 13.3 0.5 0.19 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAX99441.1 - 2.3e-09 37.2 26.6 6e-09 35.8 4.8 6.1 6 2 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX99441.1 - 0.11 12.3 0.1 0.39 10.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) RNase_HII PF01351.18 EAX99441.1 - 0.12 12.2 2.4 0.31 10.8 2.4 1.7 1 0 0 1 1 1 0 Ribonuclease HII DUF3839 PF12943.7 EAX99442.1 - 6.2e-155 513.7 13.3 7.8e-155 513.4 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAX99442.1 - 0.078 13.3 0.9 12 6.3 0.0 3.4 3 0 0 3 3 3 0 Tup N-terminal DUF4108 PF13390.6 EAX99443.1 - 1.3e-63 213.2 6.0 1.4e-63 213.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAX99444.1 - 7.6e-284 941.2 45.4 1.4e-157 525.3 16.5 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF4106) KAR PF15222.6 EAX99444.1 - 0.056 13.7 0.1 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Kidney androgen-regulated LRR_5 PF13306.6 EAX99445.1 - 3.2e-70 234.0 34.7 2.7e-26 92.0 3.0 4.2 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99445.1 - 1.6e-18 66.2 2.9 6.5e-05 22.6 0.2 6.3 4 1 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAX99445.1 - 0.00027 21.2 6.5 0.45 11.0 0.0 5.1 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAX99446.1 - 1e-17 64.3 8.0 1.4e-17 63.9 8.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99446.1 - 1.8e-05 24.4 0.0 0.00016 21.4 0.0 2.3 3 0 0 3 3 3 1 Leucine rich repeat Guanylate_cyc PF00211.20 EAX99447.1 - 1.9e-43 148.2 0.1 2.3e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SBF_like PF13593.6 EAX99448.1 - 0.019 14.3 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) YmgB PF10798.8 EAX99448.1 - 0.17 11.7 0.4 0.55 10.1 0.1 1.9 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR LPG_synthase_TM PF03706.13 EAX99449.1 - 0.1 12.1 0.1 0.1 12.1 0.1 2.1 3 0 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region Orf78 PF06024.12 EAX99449.1 - 0.14 12.4 15.2 6 7.2 0.5 4.4 4 0 0 4 4 4 0 Orf78 (ac78) DUF4064 PF13273.6 EAX99449.1 - 0.29 11.4 10.8 7.4 6.9 3.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) MFS_1 PF07690.16 EAX99449.1 - 2.7 6.8 6.2 2.3 7.1 0.2 2.7 3 0 0 3 3 3 0 Major Facilitator Superfamily SYF2 PF08231.12 EAX99452.1 - 0.032 14.6 0.6 0.067 13.6 0.1 1.7 2 0 0 2 2 2 0 SYF2 splicing factor Guanylate_cyc PF00211.20 EAX99453.1 - 4.7e-43 146.9 0.1 7.7e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAX99453.1 - 1.4e-08 34.9 0.5 4.1e-08 33.4 0.5 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EAX99453.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAX99453.1 - 0.021 14.8 0.1 0.071 13.1 0.0 1.9 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 EAX99453.1 - 0.097 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fungal_trans_2 PF11951.8 EAX99453.1 - 0.12 11.2 0.1 0.24 10.2 0.0 1.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF1924 PF09086.11 EAX99453.1 - 0.12 12.7 0.1 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) HNOBA PF07701.14 EAX99453.1 - 0.22 10.9 0.8 2.1 7.7 0.2 2.2 1 1 0 2 2 2 0 Heme NO binding associated Orf78 PF06024.12 EAX99453.1 - 0.42 10.9 2.3 2.6 8.4 0.2 2.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF5383 PF17355.2 EAX99453.1 - 1.2 9.5 7.1 0.31 11.4 1.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5383) DHHC PF01529.20 EAX99453.1 - 4.4 7.4 10.3 24 5.1 0.1 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Gly_rich PF12810.7 EAX99454.1 - 1.4e-23 84.1 36.0 1.7e-23 83.9 36.0 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX99455.1 - 4.7e-127 417.8 89.8 3.9e-26 91.5 13.8 7.6 3 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99455.1 - 9.6e-39 131.0 9.9 0.0009 19.0 0.5 12.1 11 3 4 15 15 15 9 Leucine rich repeat LRR_5 PF13306.6 EAX99456.1 - 2.7e-153 502.6 106.5 3.5e-26 91.7 2.3 7.5 3 1 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99456.1 - 4.8e-35 119.1 7.1 0.00033 20.3 0.4 11.8 9 3 3 12 12 12 9 Leucine rich repeat LRR_4 PF12799.7 EAX99456.1 - 0.77 10.3 17.4 2.7 8.5 0.1 8.3 10 1 1 11 11 11 0 Leucine Rich repeats (2 copies) TMP PF05017.14 EAX99457.1 - 1 10.3 6.2 1.6 9.7 0.5 3.9 4 2 0 3 3 3 0 TMP repeat Gly-zipper_YMGG PF13441.6 EAX99457.1 - 3.7 7.3 17.4 2.4 8.0 15.8 1.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper GAS PF13851.6 EAX99458.1 - 0.00075 18.9 28.4 0.03 13.7 0.4 4.0 3 1 0 4 4 4 2 Growth-arrest specific micro-tubule binding SOGA PF11365.8 EAX99458.1 - 0.002 19.2 13.2 0.15 13.2 3.5 2.7 2 0 0 2 2 2 2 Protein SOGA DivIC PF04977.15 EAX99458.1 - 0.0036 17.0 19.6 0.12 12.1 4.6 4.7 5 1 0 5 5 4 2 Septum formation initiator Nsp1_C PF05064.13 EAX99458.1 - 0.0049 16.6 12.2 0.032 14.0 8.5 3.2 2 1 1 3 3 3 1 Nsp1-like C-terminal region HIP1_clath_bdg PF16515.5 EAX99458.1 - 0.005 17.4 21.4 0.0052 17.4 9.2 4.3 2 1 2 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EAX99458.1 - 0.0096 16.5 24.6 0.11 13.0 15.7 3.8 3 2 0 3 3 3 1 Apg6 coiled-coil region MCC-bdg_PDZ PF10506.9 EAX99458.1 - 0.01 15.8 12.2 0.23 11.5 2.4 3.8 2 1 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Takusan PF04822.13 EAX99458.1 - 0.02 14.8 3.6 0.02 14.8 3.6 4.2 5 0 0 5 5 5 0 Takusan GCN5L1 PF06320.13 EAX99458.1 - 0.028 14.6 9.5 0.16 12.1 9.5 2.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) ATG16 PF08614.11 EAX99458.1 - 0.03 14.6 17.4 0.067 13.4 14.3 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MIS13 PF08202.11 EAX99458.1 - 0.085 12.1 13.0 0.017 14.4 8.9 1.9 2 0 0 2 2 2 0 Mis12-Mtw1 protein family CALCOCO1 PF07888.11 EAX99458.1 - 0.14 11.0 12.2 0.25 10.1 12.2 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2203 PF09969.9 EAX99458.1 - 0.15 12.8 11.4 2.8 8.7 0.5 3.8 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 EAX99458.1 - 0.2 11.9 28.4 0.33 11.2 8.2 4.4 2 2 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.6 EAX99458.1 - 0.27 11.5 10.7 0.47 10.8 4.6 3.8 3 1 1 4 4 3 0 Domain of unknown function (DUF4164) PRKG1_interact PF15898.5 EAX99458.1 - 0.28 12.1 22.0 0.17 12.8 2.5 3.4 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Csm1_N PF18504.1 EAX99458.1 - 0.51 10.7 18.8 3 8.2 7.9 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain GIT_CC PF16559.5 EAX99458.1 - 0.66 9.9 13.3 3.3 7.7 2.6 3.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 EAX99458.1 - 0.73 9.9 37.8 1.3 9.0 8.4 4.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding KASH_CCD PF14662.6 EAX99458.1 - 0.8 9.5 24.2 0.016 15.1 13.5 2.9 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH TSNAXIP1_N PF15739.5 EAX99458.1 - 0.84 10.0 13.0 1.2 9.6 7.0 3.2 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Fez1 PF06818.15 EAX99458.1 - 0.92 9.9 22.1 6.5 7.2 17.6 2.8 1 1 1 2 2 2 0 Fez1 Cep57_CLD_2 PF14197.6 EAX99458.1 - 0.98 9.6 22.4 0.5 10.5 0.4 4.7 4 1 0 5 5 4 0 Centrosome localisation domain of PPC89 FliJ PF02050.16 EAX99458.1 - 1 9.6 11.7 0.38 11.0 4.6 3.2 3 0 0 3 3 3 0 Flagellar FliJ protein CENP-H PF05837.12 EAX99458.1 - 1.4 9.4 26.1 0.16 12.4 9.3 4.4 3 1 2 5 5 5 0 Centromere protein H (CENP-H) BST2 PF16716.5 EAX99458.1 - 1.6 9.4 21.8 0.72 10.5 5.7 4.4 3 1 2 5 5 4 0 Bone marrow stromal antigen 2 DUF948 PF06103.11 EAX99458.1 - 1.7 8.9 17.3 78 3.6 0.2 4.9 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4315 PF14193.6 EAX99458.1 - 2 8.5 13.1 1.4 9.0 0.4 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) FPP PF05911.11 EAX99458.1 - 3 5.9 27.1 0.68 8.0 22.7 2.0 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2400 PF09674.10 EAX99458.1 - 3.3 7.7 8.4 5.2 7.0 1.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2400) DUF1515 PF07439.11 EAX99458.1 - 4 7.5 6.7 4 7.5 0.1 3.6 2 2 1 4 4 3 0 Protein of unknown function (DUF1515) Jnk-SapK_ap_N PF09744.9 EAX99458.1 - 4.2 7.6 21.4 0.99 9.6 14.1 3.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 EAX99458.1 - 4.6 6.5 18.1 0.76 9.0 7.4 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3450) NOG1_N PF17835.1 EAX99458.1 - 5.1 7.0 10.9 0.76 9.7 4.4 2.8 3 1 0 3 3 3 0 NOG1 N-terminal helical domain DUF4600 PF15372.6 EAX99458.1 - 5.5 7.4 20.7 0.61 10.5 11.8 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4600) DUF4407 PF14362.6 EAX99458.1 - 6.2 6.1 18.4 1.8 7.9 2.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TACC_C PF05010.14 EAX99458.1 - 6.3 6.5 24.3 2 8.2 15.3 3.0 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 EAX99458.1 - 8 7.2 8.9 13 6.4 1.5 4.0 3 1 1 4 4 4 0 SlyX Prominin PF05478.11 EAX99458.1 - 9.5 4.0 27.6 0.38 8.7 17.9 2.4 2 1 1 3 3 3 0 Prominin Fib_alpha PF08702.10 EAX99458.1 - 9.8 6.4 27.8 0.24 11.6 11.2 4.2 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family Gly_rich PF12810.7 EAX99459.1 - 3e-45 155.1 36.3 3.4e-45 154.8 36.3 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAX99460.1 - 6.2e-51 171.7 28.0 8.3e-20 71.1 6.2 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99460.1 - 6.7e-15 54.6 0.0 0.00087 19.0 0.0 4.8 3 1 2 5 5 5 4 Leucine rich repeat Gly_rich PF12810.7 EAX99462.1 - 2.9e-47 161.6 36.3 3.3e-47 161.4 36.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX99463.1 - 3e-12 47.0 31.7 3.5e-12 46.8 31.7 1.0 1 0 0 1 1 1 1 Glycine rich protein POTRA_2 PF08479.11 EAX99464.1 - 4.3 7.2 7.5 4.4 7.2 0.3 4.0 2 0 0 2 2 2 0 POTRA domain, ShlB-type DivIC PF04977.15 EAX99465.1 - 0.00099 18.8 9.4 0.00099 18.8 9.4 19.3 4 4 15 20 20 20 4 Septum formation initiator B2 PF11473.8 EAX99465.1 - 1.8 8.4 7.6 2.3 8.1 0.1 3.9 4 0 0 4 4 4 0 RNA binding protein B2 PMP1_2 PF08114.11 EAX99469.1 - 0.039 13.7 1.0 0.075 12.8 1.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family TMEM132D_C PF15706.5 EAX99469.1 - 0.069 12.9 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GPS2_interact PF15784.5 EAX99471.1 - 0.05 14.0 1.3 0.067 13.6 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX99471.1 - 0.14 11.1 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TMP PF05017.14 EAX99473.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99474.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF4200 PF13863.6 EAX99475.1 - 4.5e-15 56.1 11.1 4.5e-15 56.1 11.1 4.3 4 2 0 4 4 4 1 Domain of unknown function (DUF4200) Presenilin PF01080.17 EAX99476.1 - 6.3e-111 371.0 1.0 7.4e-111 370.7 1.0 1.0 1 0 0 1 1 1 1 Presenilin V_ATPase_I PF01496.19 EAX99476.1 - 0.0019 16.3 0.9 0.0019 16.3 0.9 1.8 1 1 1 2 2 2 1 V-type ATPase 116kDa subunit family FAM196 PF15265.6 EAX99476.1 - 0.45 10.0 14.6 0.59 9.6 14.6 1.0 1 0 0 1 1 1 0 FAM196 family Apt1 PF10351.9 EAX99476.1 - 0.57 9.0 13.2 0.78 8.5 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 EAX99476.1 - 1.3 6.0 8.3 1.7 5.7 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Flavi_NS4A PF01350.17 EAX99476.1 - 2.6 8.0 14.8 0.032 14.2 5.3 2.3 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A AF-4 PF05110.13 EAX99476.1 - 2.8 5.9 27.0 3.7 5.5 27.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GAGA_bind PF06217.12 EAX99476.1 - 2.9 8.1 9.2 3.9 7.7 9.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Lin-8 PF03353.15 EAX99476.1 - 4 6.9 15.8 5.4 6.5 15.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.6 EAX99476.1 - 6.5 5.5 9.2 9.1 5.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cwf_Cwc_15 PF04889.12 EAX99476.1 - 8 6.1 20.7 12 5.6 20.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PsbR PF04725.12 EAX99476.1 - 9.8 6.6 5.8 5 7.5 0.3 2.4 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR PWI PF01480.17 EAX99477.1 - 0.091 13.1 0.6 0.15 12.4 0.6 1.3 1 0 0 1 1 1 0 PWI domain SelP_N PF04592.14 EAX99477.1 - 1.1 8.6 25.3 0.02 14.3 17.5 2.0 2 1 0 2 2 2 0 Selenoprotein P, N terminal region PI3_PI4_kinase PF00454.27 EAX99479.1 - 5.3e-50 170.6 0.0 1.3e-49 169.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EAX99479.1 - 6.6e-19 68.4 1.9 6.6e-19 68.4 1.9 4.8 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) FATC PF02260.20 EAX99479.1 - 3e-12 46.1 0.2 8.2e-12 44.7 0.2 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EAX99479.1 - 1.9e-11 43.8 4.2 3.3e-10 39.7 4.2 2.8 1 1 0 1 1 1 1 FAT domain Vac14_Fab1_bd PF12755.7 EAX99479.1 - 0.004 17.7 2.1 0.98 10.1 0.0 4.3 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region TPR_14 PF13428.6 EAX99479.1 - 0.042 14.7 0.0 7.6 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EAX99480.1 - 4.9e-53 180.2 0.1 5.9e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99480.1 - 3.6e-30 105.1 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99480.1 - 2.5e-08 33.6 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX99480.1 - 0.0019 17.6 0.2 0.0075 15.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX99480.1 - 0.0024 16.7 0.1 0.0035 16.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase PROL5-SMR PF15621.6 EAX99481.1 - 0.0074 16.8 1.2 0.009 16.5 1.2 1.2 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family Shisa PF13908.6 EAX99481.1 - 0.056 13.7 1.4 0.072 13.3 1.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LYRIC PF15686.5 EAX99481.1 - 0.086 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MAP17 PF15807.5 EAX99481.1 - 0.11 12.8 0.4 0.17 12.1 0.4 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Beach PF02138.18 EAX99482.1 - 1.9e-19 70.1 4.6 4.8e-13 49.1 0.1 3.4 2 1 0 3 3 3 2 Beige/BEACH domain Lsr2 PF11774.8 EAX99482.1 - 0.082 13.1 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Lsr2 Urb2 PF10441.9 EAX99482.1 - 0.087 12.8 2.1 0.5 10.3 0.1 2.8 2 0 0 2 2 2 0 Urb2/Npa2 family EF-hand_1 PF00036.32 EAX99483.1 - 9.3e-26 87.4 7.3 2.3e-06 26.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX99483.1 - 8.9e-23 80.5 4.5 3.1e-11 43.6 0.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX99483.1 - 4.2e-20 69.9 7.1 8.3e-05 22.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAX99483.1 - 3.7e-19 67.3 7.1 0.00014 21.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAX99483.1 - 3.7e-17 61.9 5.3 5.4e-08 32.6 0.1 3.8 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAX99483.1 - 2e-07 31.3 3.3 0.00086 19.6 0.3 2.7 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EAX99483.1 - 0.00045 20.0 5.5 0.037 13.9 0.0 3.2 4 1 0 4 4 4 2 EF hand Toprim_2 PF13155.6 EAX99483.1 - 0.0052 17.2 1.6 0.17 12.3 0.1 2.6 1 1 0 2 2 2 1 Toprim-like SAP PF02037.27 EAX99483.1 - 0.043 13.6 0.5 13 5.7 0.0 2.6 3 0 0 3 3 3 0 SAP domain Caleosin PF05042.13 EAX99483.1 - 0.061 13.3 1.8 35 4.3 0.1 3.3 1 1 1 3 3 3 0 Caleosin related protein Excalibur PF05901.11 EAX99483.1 - 0.074 13.7 0.1 31 5.3 0.1 3.0 3 0 0 3 3 3 0 Excalibur calcium-binding domain Dockerin_1 PF00404.18 EAX99483.1 - 0.11 12.7 5.1 3.3 8.0 0.2 3.1 2 2 1 3 3 3 0 Dockerin type I domain DUF5363 PF17320.2 EAX99483.1 - 0.11 12.4 0.9 4.4 7.2 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5363) SpaA PF17802.1 EAX99483.1 - 0.15 12.4 3.0 17 5.8 3.0 2.4 1 1 0 1 1 1 0 Prealbumin-like fold domain DUF2207 PF09972.9 EAX99484.1 - 0.00098 18.0 0.0 0.0016 17.3 0.0 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) CD34_antigen PF06365.12 EAX99484.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Pacifastin_I PF05375.13 EAX99484.1 - 0.041 13.6 0.5 0.085 12.6 0.5 1.5 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) ATP-synt_8 PF00895.20 EAX99484.1 - 0.41 11.1 0.1 0.41 11.1 0.1 2.4 3 0 0 3 3 3 0 ATP synthase protein 8 CLPTM1 PF05602.12 EAX99485.1 - 2.1e-45 155.6 12.7 2.1e-45 155.6 12.7 1.5 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EAX99485.1 - 2.8e-06 27.0 1.9 0.027 14.2 0.1 3.4 3 0 0 3 3 3 2 PQ loop repeat Rnf-Nqr PF02508.14 EAX99485.1 - 0.68 9.9 4.6 2.7 7.9 0.5 2.5 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein Fringe PF02434.16 EAX99486.1 - 0.11 11.9 1.5 0.37 10.2 1.4 1.9 1 1 0 1 1 1 0 Fringe-like TRP PF06011.12 EAX99487.1 - 5e-05 22.2 4.9 5e-05 22.2 4.9 2.0 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel NT-C2 PF10358.9 EAX99489.1 - 4.8e-20 71.8 0.3 1e-19 70.7 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Cornifin PF02389.15 EAX99489.1 - 3.8e-19 69.2 67.3 0.077 13.2 0.1 18.2 3 1 16 21 21 21 12 Cornifin (SPRR) family ABC_tran_Xtn PF12848.7 EAX99490.1 - 0.22 11.5 1.3 0.74 9.9 1.3 1.9 1 0 0 1 1 1 0 ABC transporter DUF4476 PF14771.6 EAX99492.1 - 4.7e-12 46.0 0.2 7.2e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) RNA_pol_Rpb4 PF03874.16 EAX99492.1 - 0.00099 19.4 1.4 0.0013 19.1 1.2 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF3583 PF12126.8 EAX99492.1 - 0.0055 16.2 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) ASCH PF04266.14 EAX99492.1 - 0.013 16.1 1.0 0.021 15.4 0.5 1.6 1 1 1 2 2 2 0 ASCH domain TEX15 PF15326.6 EAX99492.1 - 0.018 14.8 1.5 0.022 14.5 1.5 1.0 1 0 0 1 1 1 0 Testis expressed sequence 15 ACP_PD PF04336.12 EAX99492.1 - 0.066 13.6 0.1 0.44 11.0 0.1 2.1 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Dzip-like_N PF13815.6 EAX99493.1 - 2.6e-07 30.6 2.4 2.6e-07 30.6 2.4 3.9 4 0 0 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF4407 PF14362.6 EAX99493.1 - 0.0038 16.6 10.6 0.08 12.3 6.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF4294 PF14127.6 EAX99493.1 - 0.029 14.3 0.5 0.029 14.3 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4294) zf-C2H2 PF00096.26 EAX99493.1 - 0.092 13.2 1.7 0.2 12.2 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAX99493.1 - 0.1 13.5 0.9 0.27 12.2 0.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 EAX99493.1 - 0.24 12.0 0.1 0.24 12.0 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF4446 PF14584.6 EAX99493.1 - 2.3 8.2 12.8 0.11 12.5 1.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Myb_DNA-binding PF00249.31 EAX99494.1 - 4.6e-31 106.7 5.9 3.9e-17 62.2 0.6 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99494.1 - 4.1e-22 78.2 3.9 4.6e-11 42.8 0.3 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX99494.1 - 1.7e-08 34.5 0.8 0.0014 18.7 0.0 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAX99494.1 - 1.1e-05 25.2 4.2 0.025 14.5 0.3 2.8 1 1 1 2 2 2 2 Myb DNA-binding like Exo70 PF03081.15 EAX99494.1 - 0.021 13.9 1.1 0.042 12.9 0.2 1.8 2 0 0 2 2 2 0 Exo70 exocyst complex subunit EcoEI_R_C PF08463.10 EAX99494.1 - 0.029 14.5 1.5 0.15 12.1 0.1 2.5 3 0 0 3 3 3 0 EcoEI R protein C-terminal SANT_DAMP1_like PF16282.5 EAX99494.1 - 0.063 13.5 2.6 0.29 11.4 0.1 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EAX99494.1 - 0.27 11.4 0.3 0.27 11.4 0.3 3.6 2 2 2 4 4 4 0 Myb/SANT-like DNA-binding domain Bacteriocin_IIi PF11758.8 EAX99494.1 - 0.28 11.0 1.9 5.8 6.8 0.1 2.7 2 1 0 2 2 2 0 Aureocin-like type II bacteriocin Myb_DNA-bind_4 PF13837.6 EAX99494.1 - 0.6 10.5 10.6 1 9.8 0.6 3.5 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Chromo PF00385.24 EAX99495.1 - 8.1e-06 25.7 1.8 6.8e-05 22.7 0.4 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain CAF-1_p150 PF11600.8 EAX99495.1 - 0.0013 18.5 20.5 0.0013 18.5 20.5 3.2 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMP PF05017.14 EAX99496.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99497.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ABC_tran PF00005.27 EAX99498.1 - 5e-36 124.2 0.1 1.1e-35 123.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAX99498.1 - 6.1e-29 101.5 6.3 9.8e-29 100.8 6.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region Zeta_toxin PF06414.12 EAX99498.1 - 5.9e-05 22.4 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EAX99498.1 - 8.6e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EAX99498.1 - 0.0013 18.2 1.7 0.1 12.0 0.1 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAX99498.1 - 0.0042 16.8 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EAX99498.1 - 0.0057 16.9 0.2 0.034 14.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAX99498.1 - 0.021 14.7 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 EAX99498.1 - 0.073 13.2 1.8 1.1 9.3 0.1 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EAX99498.1 - 0.086 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAX99498.1 - 0.13 11.9 0.1 0.39 10.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain SlyX PF04102.12 EAX99499.1 - 0.04 14.6 3.4 0.04 14.6 3.4 3.1 2 1 1 3 3 3 0 SlyX BTB PF00651.31 EAX99499.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain BT1 PF03092.16 EAX99499.1 - 1.7 6.8 4.0 2.7 6.1 4.0 1.2 1 0 0 1 1 1 0 BT1 family Syntaxin-6_N PF09177.11 EAX99499.1 - 6 7.5 15.8 1.4 9.5 6.2 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF3552 PF12072.8 EAX99500.1 - 0.0017 17.9 9.4 0.0017 17.9 9.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF2536 PF10750.9 EAX99500.1 - 0.0083 16.0 0.6 0.023 14.6 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2536) DUF305 PF03713.13 EAX99500.1 - 0.014 15.6 6.3 0.061 13.5 4.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF305) FliJ PF02050.16 EAX99500.1 - 0.016 15.5 11.5 0.016 15.5 11.5 3.1 1 1 2 3 3 3 0 Flagellar FliJ protein CSN8_PSD8_EIF3K PF10075.9 EAX99500.1 - 0.053 13.5 5.8 0.81 9.7 5.5 2.3 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family CRISPR_Cas2 PF09827.9 EAX99500.1 - 0.064 13.4 2.7 0.23 11.7 2.7 2.1 1 0 0 1 1 1 0 CRISPR associated protein Cas2 OmpH PF03938.14 EAX99500.1 - 0.066 13.5 22.8 0.7 10.2 14.9 3.0 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 EAX99500.1 - 0.38 10.8 22.3 0.03 14.4 15.1 2.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Flagellin_N PF00669.20 EAX99500.1 - 0.71 10.0 8.9 0.079 13.1 2.7 2.5 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region NPV_P10 PF05531.12 EAX99500.1 - 1.5 9.4 8.2 4.4 7.8 1.5 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein UPF0449 PF15136.6 EAX99500.1 - 1.9 9.0 11.3 1.6 9.3 3.2 2.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 T2SSM PF04612.12 EAX99500.1 - 4.2 7.4 8.1 3.5 7.7 2.9 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Sec5 PF15469.6 EAX99500.1 - 7.1 6.4 17.1 2.7 7.8 12.6 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec5 AI-2E_transport PF01594.16 EAX99500.1 - 8.6 5.4 5.2 22 4.1 0.2 2.4 1 1 2 3 3 3 0 AI-2E family transporter Ribosomal_S4 PF00163.19 EAX99501.1 - 7.9e-07 29.9 0.7 1.7e-06 28.9 0.5 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EAX99501.1 - 6.6e-06 25.8 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain BAR PF03114.18 EAX99502.1 - 3.8e-11 43.1 1.3 5.2e-11 42.6 1.3 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EAX99502.1 - 0.0063 16.3 7.9 0.096 12.4 2.4 2.2 1 1 1 2 2 2 2 BAR domain of APPL family Arfaptin PF06456.13 EAX99502.1 - 0.025 14.2 4.9 0.39 10.2 4.9 2.2 1 1 0 1 1 1 0 Arfaptin-like domain LPD39 PF18858.1 EAX99502.1 - 0.04 14.0 2.5 0.069 13.2 2.5 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 SHE3 PF17078.5 EAX99503.1 - 0.0086 15.8 3.0 0.09 12.5 0.4 2.4 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 CEP63 PF17045.5 EAX99503.1 - 0.025 14.5 3.6 0.11 12.4 0.3 2.2 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa ParB PF08775.10 EAX99503.1 - 0.1 13.1 1.6 0.3 11.6 0.2 2.5 2 0 0 2 2 2 0 ParB family TMPIT PF07851.13 EAX99503.1 - 0.48 9.6 5.1 0.21 10.8 0.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 EAX99503.1 - 2.8 8.1 9.5 3.1 7.9 0.1 3.5 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase CFAP91 PF14738.6 EAX99504.1 - 4e-15 56.2 22.0 1.1e-10 41.7 14.8 4.4 3 2 1 4 4 4 2 Cilia- and flagella-associated protein 91 PMSR PF01625.21 EAX99504.1 - 0.38 10.9 3.2 1.4 9.1 0.0 2.9 2 1 0 2 2 2 0 Peptide methionine sulfoxide reductase Ank_2 PF12796.7 EAX99505.1 - 2.4e-16 60.1 2.7 1.6e-14 54.2 0.2 3.3 1 1 3 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99505.1 - 7.4e-13 47.4 0.5 7.8e-05 22.8 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX99505.1 - 4.8e-12 46.1 0.1 6e-09 36.3 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99505.1 - 3.7e-10 39.9 0.0 6e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99505.1 - 2.3e-06 27.8 0.0 0.00047 20.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PPR_long PF17177.4 EAX99505.1 - 0.015 14.7 0.2 0.061 12.7 0.1 2.0 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP MobB PF03205.14 EAX99506.1 - 0.26 11.2 4.9 10 6.0 4.9 2.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_4 PF13637.6 EAX99507.1 - 1.3e-76 252.0 25.6 5.4e-10 39.6 0.1 11.9 3 1 9 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX99507.1 - 5.2e-74 241.7 22.3 8.9e-08 32.3 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_2 PF12796.7 EAX99507.1 - 3.6e-70 232.6 33.4 9.8e-21 74.1 4.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99507.1 - 5.6e-54 179.5 17.7 8.4e-13 48.3 0.1 8.6 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99507.1 - 1.6e-53 172.4 28.1 8.8e-05 22.6 0.0 12.7 12 1 0 12 12 12 9 Ankyrin repeat DUF3447 PF11929.8 EAX99507.1 - 7.4e-40 134.8 6.2 7.4e-40 134.8 6.2 5.6 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) EHN PF06441.12 EAX99507.1 - 0.0062 16.9 0.3 11 6.4 0.0 3.8 3 1 0 3 3 3 1 Epoxide hydrolase N terminus BRCT_2 PF16589.5 EAX99507.1 - 0.04 14.3 10.1 2.5 8.6 0.2 4.6 1 1 4 5 5 5 0 BRCT domain, a BRCA1 C-terminus domain DUF4147 PF13660.6 EAX99507.1 - 0.085 12.4 4.4 10 5.6 0.1 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF4147) BRCT PF00533.26 EAX99507.1 - 0.24 11.8 2.3 16 6.0 0.5 3.7 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain SAB PF04382.13 EAX99507.1 - 0.85 9.8 5.8 80 3.4 0.0 4.9 5 0 0 5 5 5 0 SAB domain Ribosomal_S6 PF01250.17 EAX99507.1 - 1.5 9.2 5.1 39 4.6 0.1 3.9 3 2 2 5 5 5 0 Ribosomal protein S6 TPT PF03151.16 EAX99508.1 - 7e-13 48.6 23.5 7.9e-13 48.4 23.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAX99508.1 - 0.024 14.8 34.5 0.026 14.7 10.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family Chordopox_A13L PF05961.11 EAX99508.1 - 0.025 14.8 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PAP2 PF01569.21 EAX99509.1 - 1.9e-23 82.8 1.6 1.9e-23 82.8 1.6 2.2 1 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EAX99509.1 - 0.0015 19.0 0.1 0.0015 19.0 0.1 2.6 3 1 1 4 4 4 1 PAP2 superfamily C-terminal Na_Ala_symp PF01235.17 EAX99509.1 - 0.012 15.0 1.7 0.44 9.8 0.1 2.4 1 1 2 3 3 3 0 Sodium:alanine symporter family CrgA PF06781.12 EAX99509.1 - 0.017 15.2 0.7 0.043 13.9 0.1 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Tim17 PF02466.19 EAX99509.1 - 0.061 13.7 0.2 0.17 12.2 0.2 2.0 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Yip1 PF04893.17 EAX99509.1 - 0.19 11.4 10.0 1.4 8.6 5.3 2.7 2 1 0 2 2 2 0 Yip1 domain 7tm_7 PF08395.12 EAX99509.1 - 0.36 10.0 5.6 0.097 11.9 2.1 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor Per1 PF04080.13 EAX99509.1 - 0.62 9.8 3.2 0.52 10.0 0.2 2.0 1 1 0 2 2 2 0 Per1-like family DUF420 PF04238.12 EAX99509.1 - 4.3 7.6 8.8 0.71 10.2 0.4 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF420) Presenilin PF01080.17 EAX99509.1 - 5.3 5.7 6.1 0.26 10.0 0.6 1.6 2 0 0 2 2 2 0 Presenilin Myb_DNA-binding PF00249.31 EAX99511.1 - 1.9e-05 24.7 0.1 5.6e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99511.1 - 0.0052 17.0 0.7 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 EAX99511.1 - 0.0069 16.7 0.0 0.08 13.3 0.0 2.6 2 0 0 2 2 2 1 SWIRM domain PRIMA1 PF16101.5 EAX99512.1 - 0.00016 21.7 2.5 0.00021 21.3 2.5 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 ECSCR PF15820.5 EAX99512.1 - 0.0032 17.3 1.2 0.0044 16.8 1.2 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Collectrin PF16959.5 EAX99512.1 - 0.0055 16.5 3.2 0.0082 15.9 3.2 1.3 1 0 0 1 1 1 1 Renal amino acid transporter MFS_Mycoplasma PF07672.13 EAX99512.1 - 0.019 14.3 0.6 0.022 14.1 0.6 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF3827 PF12877.7 EAX99512.1 - 0.034 12.5 2.1 0.041 12.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NS3_envE PF02723.14 EAX99512.1 - 0.035 14.2 4.1 0.035 14.2 4.1 1.6 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E TMEM132D_C PF15706.5 EAX99512.1 - 0.06 13.1 0.6 0.1 12.4 0.6 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cadherin_C_2 PF16492.5 EAX99512.1 - 0.074 13.8 1.1 0.1 13.3 1.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 EAX99512.1 - 0.096 12.9 1.0 0.1 12.8 1.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Insulin_TMD PF17870.1 EAX99512.1 - 0.92 9.6 7.2 0.98 9.5 6.4 1.5 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment WD40 PF00400.32 EAX99513.1 - 4.4e-29 100.1 12.6 5.2e-07 30.3 0.5 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX99513.1 - 5.2e-15 55.5 0.0 0.0057 16.9 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAX99513.1 - 6.1e-10 38.9 0.0 0.00056 19.3 0.0 3.4 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EAX99513.1 - 5.4e-08 32.2 5.3 0.012 14.6 0.1 4.9 3 1 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 EAX99513.1 - 0.024 14.2 0.2 0.52 9.9 0.1 2.7 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region GspH PF12019.8 EAX99513.1 - 0.045 14.2 0.2 12 6.4 0.0 3.2 1 1 1 3 3 3 0 Type II transport protein GspH CH PF00307.31 EAX99514.1 - 0.11 12.7 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain PTR PF12789.7 EAX99516.1 - 5.7e-17 61.5 1.4 5.7e-17 61.5 1.4 4.2 5 1 0 5 5 5 1 Phage tail repeat like DUF4795 PF16043.5 EAX99516.1 - 0.0088 15.7 1.4 0.0088 15.7 1.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4795) DUF3391 PF11871.8 EAX99516.1 - 0.85 10.2 3.7 0.93 10.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF836 PF05768.14 EAX99517.1 - 0.0099 16.3 0.8 0.015 15.7 0.7 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-C2H2_assoc2 PF16624.5 EAX99517.1 - 0.39 11.8 8.0 0.53 11.3 8.0 1.3 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger Ank_2 PF12796.7 EAX99518.1 - 1.9e-09 38.0 2.5 1.7e-07 31.7 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99518.1 - 2.4e-08 34.1 0.0 1.7e-05 25.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99518.1 - 6.5e-08 33.0 0.2 0.042 14.5 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99518.1 - 1.3e-06 28.6 0.6 0.00055 20.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAX99518.1 - 1.8e-06 27.8 0.3 0.01 16.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat AvrPtoB-E3_ubiq PF09046.10 EAX99518.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase LytR_cpsA_psr PF03816.14 EAX99518.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain DUF4495 PF14906.6 EAX99519.1 - 0.0026 16.9 1.5 0.01 14.9 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4495) DUF285 PF03382.14 EAX99519.1 - 0.049 13.4 0.4 0.46 10.2 0.1 2.2 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Mad3_BUB1_I PF08311.12 EAX99519.1 - 0.1 12.6 0.2 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Ribosomal_L22e PF01776.17 EAX99520.1 - 7e-27 94.0 1.1 7.6e-27 93.9 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1912 PF08930.10 EAX99520.1 - 0.021 14.9 0.3 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Beta_helix PF13229.6 EAX99521.1 - 1.5e-60 203.6 76.4 5.9e-15 55.5 15.1 5.6 1 1 5 6 6 6 6 Right handed beta helix region NosD PF05048.13 EAX99521.1 - 1.3e-30 106.4 43.6 1.6e-08 34.2 9.5 5.1 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Pentapeptide_4 PF13599.6 EAX99521.1 - 0.00033 20.8 18.6 0.012 15.8 7.5 5.7 3 2 3 6 6 6 3 Pentapeptide repeats (9 copies) Pectate_lyase_3 PF12708.7 EAX99521.1 - 0.077 12.8 45.7 1.7 8.4 8.5 5.8 2 2 2 4 4 4 0 Pectate lyase superfamily protein APG6_N PF17675.1 EAX99522.1 - 6e-06 26.8 2.1 1e-05 26.1 2.1 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF812 PF05667.11 EAX99522.1 - 8.8e-06 24.9 6.4 1.1e-05 24.5 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 EAX99522.1 - 1.1e-05 24.5 4.2 1.6e-05 24.0 4.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein SKA2 PF16740.5 EAX99522.1 - 1.6e-05 24.6 3.9 2.7e-05 23.9 3.9 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 ATG16 PF08614.11 EAX99522.1 - 7e-05 23.2 6.6 0.0001 22.6 6.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EAX99522.1 - 9.3e-05 22.2 4.7 0.00016 21.5 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 EAX99522.1 - 0.00015 22.0 5.7 0.0023 18.1 5.8 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EAX99522.1 - 0.00015 21.9 5.0 0.00022 21.3 5.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 EAX99522.1 - 0.00056 20.4 3.1 0.0023 18.5 1.0 2.6 1 1 1 2 2 2 1 Syntaxin 6, N-terminal LPP PF04728.13 EAX99522.1 - 0.00094 19.5 1.5 0.00094 19.5 1.5 2.8 2 1 1 3 3 2 1 Lipoprotein leucine-zipper Leu_zip PF15294.6 EAX99522.1 - 0.0011 18.5 4.9 0.0016 18.1 4.9 1.2 1 0 0 1 1 1 1 Leucine zipper Golgin_A5 PF09787.9 EAX99522.1 - 0.0012 18.4 3.7 0.0015 18.0 3.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 EAX99522.1 - 0.0013 18.9 4.3 0.0022 18.2 4.3 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TSC22 PF01166.18 EAX99522.1 - 0.0017 18.6 3.4 0.0067 16.7 1.7 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family USP8_interact PF08941.10 EAX99522.1 - 0.0019 18.0 0.8 0.0063 16.4 0.6 1.9 2 0 0 2 2 2 1 USP8 interacting Lebercilin PF15619.6 EAX99522.1 - 0.0021 17.8 6.6 0.0032 17.2 6.6 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HAUS5 PF14817.6 EAX99522.1 - 0.0026 16.6 1.6 0.0033 16.3 1.6 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 HAP1_N PF04849.13 EAX99522.1 - 0.0027 17.0 3.3 0.0037 16.5 3.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region MIS13 PF08202.11 EAX99522.1 - 0.0031 16.8 5.2 0.0041 16.5 5.2 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family GPS2_interact PF15784.5 EAX99522.1 - 0.0035 17.7 2.8 2.1 8.9 0.0 2.5 1 1 1 2 2 2 1 G-protein pathway suppressor 2-interacting domain ZapB PF06005.12 EAX99522.1 - 0.0042 17.5 8.6 0.0093 16.4 8.6 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DUF641 PF04859.12 EAX99522.1 - 0.0045 17.3 3.2 0.0072 16.7 3.2 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Atg14 PF10186.9 EAX99522.1 - 0.0051 15.9 4.7 0.0068 15.5 4.7 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 EAX99522.1 - 0.0053 17.5 0.9 0.0097 16.6 0.9 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) THOC7 PF05615.13 EAX99522.1 - 0.0066 16.7 8.8 0.025 14.8 8.1 2.0 1 1 0 2 2 2 1 Tho complex subunit 7 DUF4200 PF13863.6 EAX99522.1 - 0.0072 16.7 11.4 0.12 12.8 11.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) DUF724 PF05266.14 EAX99522.1 - 0.0082 16.0 9.2 0.017 14.9 9.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF724) UPF0242 PF06785.11 EAX99522.1 - 0.0092 16.1 5.3 0.012 15.7 5.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL6 PF01763.16 EAX99522.1 - 0.0098 14.5 2.8 0.011 14.3 2.8 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like BRE1 PF08647.11 EAX99522.1 - 0.01 15.9 12.0 0.015 15.4 11.0 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EAX99522.1 - 0.011 15.7 9.1 0.021 14.9 9.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 EAX99522.1 - 0.012 16.0 2.4 0.02 15.2 2.4 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3287 PF11690.8 EAX99522.1 - 0.012 15.3 0.3 0.025 14.3 0.2 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3287) Ax_dynein_light PF10211.9 EAX99522.1 - 0.013 15.5 8.2 0.02 14.9 8.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DivIC PF04977.15 EAX99522.1 - 0.013 15.2 7.4 0.13 12.0 7.7 2.5 2 1 0 2 2 1 0 Septum formation initiator GAS PF13851.6 EAX99522.1 - 0.015 14.6 10.2 0.022 14.1 9.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EAX99522.1 - 0.019 14.8 11.2 0.03 14.2 10.8 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3231 PF11553.8 EAX99522.1 - 0.021 14.5 4.6 0.37 10.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) Talin_middle PF09141.10 EAX99522.1 - 0.022 14.8 0.2 0.031 14.3 0.2 1.2 1 0 0 1 1 1 0 Talin, middle domain Ank_3 PF13606.6 EAX99522.1 - 0.022 15.2 0.0 0.084 13.5 0.0 2.0 2 0 0 2 2 1 0 Ankyrin repeat PspA_IM30 PF04012.12 EAX99522.1 - 0.023 14.3 2.9 0.042 13.4 2.9 1.4 1 0 0 1 1 1 0 PspA/IM30 family bZIP_1 PF00170.21 EAX99522.1 - 0.031 14.4 4.5 0.031 14.4 4.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor Ank_2 PF12796.7 EAX99522.1 - 0.032 14.8 0.1 0.1 13.2 0.0 1.9 2 1 0 2 2 1 0 Ankyrin repeats (3 copies) Cep57_MT_bd PF06657.13 EAX99522.1 - 0.033 14.6 2.2 0.15 12.5 2.2 2.0 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 V-SNARE PF05008.15 EAX99522.1 - 0.034 14.5 9.0 0.91 9.9 8.1 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4472 PF14739.6 EAX99522.1 - 0.034 14.9 5.8 0.066 14.0 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Troponin PF00992.20 EAX99522.1 - 0.04 14.2 5.2 0.07 13.4 5.2 1.3 1 0 0 1 1 1 0 Troponin CENP-F_leu_zip PF10473.9 EAX99522.1 - 0.052 13.6 9.0 0.11 12.5 8.2 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RILP PF11461.8 EAX99522.1 - 0.056 13.7 4.6 0.1 12.8 3.1 2.1 1 1 2 3 3 2 0 Rab interacting lysosomal protein T2SSM PF04612.12 EAX99522.1 - 0.06 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M P4Ha_N PF08336.11 EAX99522.1 - 0.06 13.4 3.9 0.14 12.2 3.9 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4407 PF14362.6 EAX99522.1 - 0.071 12.5 1.3 0.1 11.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF465 PF04325.13 EAX99522.1 - 0.081 13.0 0.5 0.16 12.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF1664 PF07889.12 EAX99522.1 - 0.084 12.9 1.3 0.16 12.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EAX99522.1 - 0.089 13.2 7.7 0.15 12.5 7.7 1.4 1 1 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.22 EAX99522.1 - 0.099 12.9 9.1 0.22 11.7 7.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1844 PF08899.11 EAX99522.1 - 0.1 12.9 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) YlqD PF11068.8 EAX99522.1 - 0.12 12.7 6.2 0.22 11.9 6.2 1.4 1 0 0 1 1 1 0 YlqD protein DUF489 PF04356.12 EAX99522.1 - 0.16 12.0 2.3 0.24 11.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF4094 PF13334.6 EAX99522.1 - 0.16 12.4 5.2 0.15 12.5 2.8 2.2 1 1 1 2 2 1 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.12 EAX99522.1 - 0.18 11.7 1.3 4.7 7.2 0.0 3.4 3 1 1 4 4 3 0 Viral A-type inclusion protein repeat Exonuc_VII_L PF02601.15 EAX99522.1 - 0.18 11.3 2.4 0.22 11.1 2.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_2 PF07716.15 EAX99522.1 - 0.22 11.7 9.7 0.28 11.3 1.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Cauli_DNA-bind PF03310.13 EAX99522.1 - 0.26 11.4 4.3 0.14 12.3 0.4 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein SOGA PF11365.8 EAX99522.1 - 0.3 12.2 6.3 1 10.5 4.4 2.5 1 1 2 3 3 3 0 Protein SOGA ABC_tran_CTD PF16326.5 EAX99522.1 - 0.3 11.3 6.9 0.92 9.8 6.9 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain HalX PF08663.10 EAX99522.1 - 0.43 10.9 2.3 2.2 8.7 0.5 2.3 1 1 1 2 2 2 0 HalX domain DUF4140 PF13600.6 EAX99522.1 - 0.44 11.0 2.4 1.4 9.4 2.5 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.7 EAX99522.1 - 0.45 10.7 9.9 0.96 9.6 9.0 2.0 1 1 1 2 2 1 0 Tropomyosin like DUF3450 PF11932.8 EAX99522.1 - 0.48 9.7 6.2 0.71 9.1 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 EAX99522.1 - 0.62 10.7 6.9 1.4 9.6 6.5 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 EAX99522.1 - 0.65 10.1 6.1 1.9 8.6 5.6 2.1 1 1 0 1 1 1 0 Swi5 HIP1_clath_bdg PF16515.5 EAX99522.1 - 0.86 10.3 7.9 1.5 9.5 7.9 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cep57_CLD_2 PF14197.6 EAX99522.1 - 0.91 9.7 5.7 2.7 8.1 4.0 2.4 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 Tup_N PF08581.10 EAX99522.1 - 1 9.7 11.2 0.43 10.9 7.4 2.4 2 2 0 2 2 1 0 Tup N-terminal BST2 PF16716.5 EAX99522.1 - 1.6 9.4 9.8 0.3 11.7 3.1 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF1043 PF06295.12 EAX99522.1 - 2.3 8.2 8.5 1.3 9.1 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) FapA PF03961.13 EAX99522.1 - 2.3 6.7 12.0 2.9 6.4 11.0 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A GrpE PF01025.19 EAX99522.1 - 2.9 7.5 10.5 2.4 7.8 7.5 2.2 1 1 0 2 2 2 0 GrpE DUF16 PF01519.16 EAX99522.1 - 4 8.0 12.0 10 6.7 12.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 FliD_N PF02465.18 EAX99522.1 - 5.3 7.8 13.2 36 5.1 2.7 2.5 1 1 2 3 3 2 0 Flagellar hook-associated protein 2 N-terminus TMF_DNA_bd PF12329.8 EAX99522.1 - 9.9 6.3 15.2 2.2 8.4 10.3 2.3 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Ank_2 PF12796.7 EAX99523.1 - 4.9e-21 75.1 0.1 3.1e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99523.1 - 2.6e-19 69.0 0.0 3.4e-10 40.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99523.1 - 2e-16 60.1 0.0 5.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99523.1 - 2.8e-13 49.7 0.0 0.056 13.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX99523.1 - 6.7e-12 44.5 0.0 0.0012 19.1 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat MULE PF10551.9 EAX99524.1 - 1.4e-10 41.4 2.2 5.3e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAX99524.1 - 0.0042 17.2 2.2 0.014 15.5 2.2 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAX99524.1 - 0.0049 15.8 0.3 0.0085 15.0 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family PSP PF04046.16 EAX99525.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99526.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Phage_fiber PF03335.13 EAX99528.1 - 0.23 11.7 4.8 2.1 8.8 0.3 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat KilA-N PF04383.13 EAX99530.1 - 5.5e-33 113.2 0.1 1.2e-32 112.1 0.1 1.6 1 0 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAX99531.1 - 1e-06 29.2 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAX99531.1 - 0.0096 15.5 0.5 0.046 13.3 0.2 1.9 2 0 0 2 2 2 1 Legume lectin domain KilA-N PF04383.13 EAX99531.1 - 0.034 14.0 0.8 0.23 11.3 0.2 2.4 2 1 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAX99532.1 - 1.7e-156 518.8 14.5 2.2e-156 518.5 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99532.1 - 0.5 10.9 6.3 2.1 8.9 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 EAX99532.1 - 0.54 10.6 2.5 2.7 8.3 0.0 3.0 2 2 1 3 3 3 0 Rx N-terminal domain DUF1493 PF07377.12 EAX99533.1 - 0.029 14.8 0.6 0.076 13.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99534.1 - 0.037 14.5 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99535.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank PF00023.30 EAX99536.1 - 7.9e-08 32.4 0.3 0.0093 16.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAX99536.1 - 5.1e-06 26.4 0.1 0.19 12.4 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAX99536.1 - 6.7e-06 26.6 0.1 8e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99536.1 - 2.4e-05 24.8 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99536.1 - 0.00026 21.2 0.1 0.00034 20.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99537.1 - 4.2e-98 322.1 55.8 1.8e-19 70.1 4.6 8.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99537.1 - 2.4e-87 286.3 25.6 6.4e-14 52.1 0.1 12.6 4 3 9 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EAX99537.1 - 5.8e-74 241.5 17.4 1.1e-08 35.1 0.0 12.3 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAX99537.1 - 1.1e-70 232.7 24.1 2e-11 43.9 0.2 9.4 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99537.1 - 1.3e-63 203.4 14.5 3.7e-06 26.8 0.0 14.4 13 1 1 14 14 14 11 Ankyrin repeat DUF3447 PF11929.8 EAX99537.1 - 8.6e-39 131.4 1.8 8.6e-39 131.4 1.8 5.7 4 2 4 8 8 8 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX99538.1 - 8.8e-13 48.2 0.8 2.4e-12 46.8 0.6 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99538.1 - 6.6e-12 45.3 4.3 1.7e-06 28.2 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX99538.1 - 3.1e-11 43.6 1.9 1.7e-10 41.2 0.2 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99538.1 - 9e-11 42.2 0.6 3.1e-10 40.5 0.6 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99538.1 - 1.7e-09 37.1 0.7 8.6e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 EAX99538.1 - 1.1e-06 28.4 10.6 1.1e-06 28.4 10.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX99538.1 - 4.2e-06 26.5 11.4 1.1e-05 25.2 11.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAX99538.1 - 1.3 9.0 17.7 0.33 11.0 13.2 2.4 2 1 1 3 3 3 0 zinc-RING finger domain Ras PF00071.22 EAX99539.1 - 9.2e-47 158.7 0.0 1.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99539.1 - 3.1e-33 114.5 0.1 4.6e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99539.1 - 2.8e-17 62.7 0.0 3.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX99539.1 - 4e-08 33.3 0.0 6.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99539.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX99539.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX99539.1 - 2e-05 24.6 0.0 0.038 13.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAX99539.1 - 0.00023 20.8 0.0 0.033 13.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAX99539.1 - 0.0023 18.0 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_15 PF13175.6 EAX99539.1 - 0.0048 16.6 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAX99539.1 - 0.0075 15.8 0.0 0.076 12.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EAX99539.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 AIG1 family PduV-EutP PF10662.9 EAX99539.1 - 0.023 14.4 0.0 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAX99539.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EAX99539.1 - 0.046 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 EAX99539.1 - 0.088 13.2 0.0 0.097 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Malic_M PF03949.15 EAX99540.1 - 2.9e-30 105.4 6.2 4.8e-29 101.4 6.2 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAX99540.1 - 4.6e-30 104.8 0.0 3.5e-21 75.8 0.0 2.8 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain ELFV_dehydrog PF00208.21 EAX99540.1 - 0.0029 17.4 0.7 0.0047 16.7 0.7 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EAX99540.1 - 0.0061 15.9 4.3 0.011 15.1 4.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EAX99540.1 - 0.025 13.9 1.0 0.062 12.7 0.8 1.7 1 1 0 1 1 1 0 ThiF family Gly_rich PF12810.7 EAX99541.1 - 2.6e-14 53.7 3.3 2.8e-14 53.6 3.3 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3781 PF12636.7 EAX99542.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDR PF08841.10 EAX99543.1 - 0.12 11.3 0.1 0.14 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX99545.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_pol_B_2 PF03175.13 EAX99546.1 - 1.5e-30 106.6 13.2 5.5e-30 104.7 13.2 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAX99546.1 - 0.11 12.4 0.1 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAX99547.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX99547.1 - 0.07 13.1 0.5 0.1 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2939 PF11159.8 EAX99548.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX99548.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAX99549.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAX99550.1 - 0.095 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAX99551.1 - 0.098 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAX99551.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF3839 PF12943.7 EAX99552.1 - 2.6e-146 485.5 14.5 3.2e-146 485.2 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) FKBP_N PF01346.18 EAX99552.1 - 0.72 10.9 3.5 0.66 11.0 0.9 2.2 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase KELK PF15796.5 EAX99552.1 - 0.8 10.2 5.0 1.5 9.3 0.3 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glu-tRNAGln PF02686.15 EAX99552.1 - 1.2 9.5 3.6 1 9.7 0.9 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Amidase02_C PF12123.8 EAX99554.1 - 0.0095 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX99555.1 - 8.5e-70 234.1 3.0 1.2e-69 233.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3781 PF12636.7 EAX99556.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Gly_rich PF12810.7 EAX99557.1 - 5.7e-14 52.6 6.9 6.1e-14 52.5 6.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAX99558.1 - 3.9e-30 105.6 39.7 5.1e-30 105.2 39.7 1.1 1 0 0 1 1 1 1 Glycine rich protein BACK PF07707.15 EAX99559.1 - 0.013 15.6 0.3 0.035 14.2 0.3 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch HEAT_2 PF13646.6 EAX99560.1 - 0.013 15.8 1.0 3.1 8.3 0.0 4.0 5 0 0 5 5 5 0 HEAT repeats DUF1779 PF08680.10 EAX99560.1 - 0.015 15.5 0.6 0.067 13.4 0.6 2.1 1 0 0 1 1 1 0 TATA-box binding DUF3347 PF11827.8 EAX99560.1 - 0.037 14.2 0.4 0.99 9.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) RasGEF_N_2 PF14663.6 EAX99560.1 - 0.042 14.2 2.1 2.7 8.4 0.1 4.3 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Katanin_con80 PF13925.6 EAX99560.1 - 4.9 7.2 8.4 1.3 9.0 0.3 3.6 4 0 0 4 4 4 0 con80 domain of Katanin Ank_3 PF13606.6 EAX99561.1 - 0.00016 21.9 0.7 9.4 7.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAX99561.1 - 0.00025 21.5 0.3 0.26 11.9 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99561.1 - 0.0012 19.4 0.2 8.9 7.0 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99561.1 - 0.011 15.7 3.7 0.011 15.7 3.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Pkinase PF00069.25 EAX99563.1 - 3.2e-25 89.0 0.0 4.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99563.1 - 1.7e-14 53.8 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99563.1 - 3.3e-05 23.3 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-rbx1 PF12678.7 EAX99564.1 - 3.8e-19 68.7 12.3 3.8e-19 68.7 12.3 1.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAX99564.1 - 2.5e-14 53.1 4.3 2.9e-14 52.9 4.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAX99564.1 - 1.2e-07 32.0 15.2 6.5e-07 29.6 15.2 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX99564.1 - 7.4e-05 22.5 8.7 7.4e-05 22.5 8.7 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX99564.1 - 0.00024 20.9 12.0 0.00085 19.1 12.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAX99564.1 - 0.0015 18.4 12.2 0.027 14.4 8.3 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAX99564.1 - 0.0035 17.3 10.9 0.015 15.3 10.9 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.14 EAX99564.1 - 0.0044 16.7 6.6 0.51 10.0 0.2 2.5 2 1 0 2 2 2 2 P-11 zinc finger zf-Nse PF11789.8 EAX99564.1 - 0.01 15.6 6.3 0.074 12.9 6.2 2.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1978 PF09321.10 EAX99564.1 - 0.023 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) zf-RING-like PF08746.11 EAX99564.1 - 0.03 14.6 9.2 0.03 14.6 9.2 1.9 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 EAX99564.1 - 0.044 14.0 11.3 0.19 11.9 11.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EAX99564.1 - 0.048 13.5 12.3 4.2 7.3 12.4 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAX99564.1 - 0.053 13.1 13.3 0.31 10.7 13.3 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EAX99564.1 - 0.45 10.6 11.8 1.7 8.8 0.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.6 EAX99564.1 - 0.57 10.5 11.7 2.9 8.2 11.7 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3H2C3 PF17122.5 EAX99564.1 - 7 6.8 15.7 2.8 8.0 9.7 2.7 2 1 0 2 2 2 0 Zinc-finger VPS13 PF16908.5 EAX99565.1 - 7.2e-26 91.4 1.6 4.6e-24 85.5 0.1 3.9 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EAX99565.1 - 6.5e-21 74.6 5.6 6.8e-20 71.3 0.1 4.3 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EAX99565.1 - 5.7e-11 42.5 4.8 3.5e-06 26.9 0.3 4.1 2 1 1 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EAX99565.1 - 8.2e-06 26.1 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Ank_2 PF12796.7 EAX99567.1 - 5.3e-07 30.1 0.0 0.0026 18.3 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99567.1 - 3e-05 24.1 0.0 1.4 9.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAX99567.1 - 0.00029 20.8 2.5 0.00036 20.4 0.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX99567.1 - 0.00051 20.6 0.0 0.39 11.4 0.0 3.3 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99567.1 - 0.074 13.5 0.0 23 5.7 0.0 3.1 4 1 0 4 4 4 0 Ankyrin repeat Ribosomal_L2_C PF03947.18 EAX99568.1 - 1.7e-39 134.9 2.4 2.8e-39 134.2 2.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAX99568.1 - 9.2e-17 60.8 0.0 4e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Bac_GDH PF05088.12 EAX99569.1 - 0.008 13.7 0.1 0.012 13.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase Mob_synth_C PF06463.13 EAX99569.1 - 0.022 14.7 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-C2H2_4 PF13894.6 EAX99569.1 - 0.74 10.8 8.8 0.58 11.2 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAX99569.1 - 9.6 6.9 8.1 17 6.1 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ank_2 PF12796.7 EAX99570.1 - 2.1e-59 198.0 9.1 1.3e-19 70.6 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99570.1 - 3.8e-35 119.8 4.8 4.6e-08 33.5 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX99570.1 - 3.6e-34 115.7 5.8 2.6e-06 27.6 0.3 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAX99570.1 - 5.6e-32 106.2 0.3 9.1e-05 22.6 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAX99570.1 - 3.1e-28 97.4 2.4 4.6e-07 30.0 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) CoaE PF01121.20 EAX99571.1 - 0.1 12.3 0.0 0.44 10.2 0.0 2.1 3 0 0 3 3 3 0 Dephospho-CoA kinase AAA_22 PF13401.6 EAX99571.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-rbx1 PF12678.7 EAX99572.1 - 1.4e-19 70.1 12.4 1.4e-19 70.1 12.4 1.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAX99572.1 - 6.9e-15 54.9 3.7 7.9e-15 54.7 3.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAX99572.1 - 7.1e-08 32.7 15.2 4.2e-07 30.2 15.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAX99572.1 - 2.2e-05 24.2 10.8 5e-05 23.1 10.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAX99572.1 - 6e-05 22.8 9.0 6e-05 22.8 9.0 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAX99572.1 - 0.00074 19.4 12.4 0.01 15.8 9.2 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAX99572.1 - 0.002 18.1 11.0 0.01 15.9 11.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger DUF1978 PF09321.10 EAX99572.1 - 0.0062 15.9 0.1 0.0078 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) zf-RING-like PF08746.11 EAX99572.1 - 0.0082 16.4 8.9 0.0082 16.4 8.9 1.9 2 0 0 2 2 2 1 RING-like domain zf-Nse PF11789.8 EAX99572.1 - 0.0084 15.9 5.5 0.029 14.2 5.4 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 EAX99572.1 - 0.0097 15.6 7.1 0.48 10.1 0.2 2.6 2 1 1 3 3 3 2 P-11 zinc finger zf-C3HC4_3 PF13920.6 EAX99572.1 - 0.026 14.4 12.4 2.2 8.2 12.2 2.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAX99572.1 - 0.054 13.1 13.0 0.33 10.6 13.0 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EAX99572.1 - 0.059 13.6 11.9 0.25 11.5 11.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.10 EAX99572.1 - 0.15 12.2 0.4 0.15 12.2 0.4 2.7 2 1 1 3 3 2 0 Zinc ribbon domain DUF1307 PF06998.11 EAX99572.1 - 0.21 11.6 2.6 0.28 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) zf-HC5HC2H PF13771.6 EAX99572.1 - 0.21 11.8 11.9 1.3 9.4 11.9 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain DZR PF12773.7 EAX99572.1 - 1.1 9.4 12.0 3.2e+02 1.4 12.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon TAFII28 PF04719.14 EAX99573.1 - 0.067 13.3 0.2 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Sel1 PF08238.12 EAX99574.1 - 2e-16 60.0 1.2 2.2e-08 34.5 0.1 5.4 5 0 0 5 5 5 3 Sel1 repeat Pkinase PF00069.25 EAX99574.1 - 3.1e-05 23.5 2.4 0.011 15.1 2.2 2.5 2 0 0 2 2 2 2 Protein kinase domain Ank PF00023.30 EAX99575.1 - 2.2e-43 144.9 0.6 2.2e-08 34.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX99575.1 - 2e-39 134.1 5.1 4.4e-19 68.8 0.3 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99575.1 - 3.6e-39 132.6 0.3 4.5e-12 46.2 0.0 7.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99575.1 - 5.6e-37 125.5 6.3 5.6e-37 125.5 6.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX99575.1 - 2.9e-32 110.3 0.1 3.5e-12 46.3 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99575.1 - 2.8e-30 101.0 4.9 0.00024 21.3 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat MetallophosN PF16371.5 EAX99575.1 - 0.0082 16.4 0.0 1.3 9.4 0.0 3.4 2 1 3 5 5 5 2 N terminal of Calcineurin-like phosphoesterase DUF4108 PF13390.6 EAX99576.1 - 8.7e-62 207.3 8.2 9.6e-62 207.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAX99578.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99578.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99578.1 - 4.9e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99578.1 - 0.00014 21.9 3.2 0.00031 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99578.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX99578.1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX99578.1 - 0.0012 18.5 0.5 0.0096 15.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99578.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX99578.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX99578.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX99578.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX99578.1 - 0.39 11.0 3.9 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX99579.1 - 3.9e-34 116.9 0.3 1e-33 115.5 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAX99579.1 - 0.084 13.6 1.0 21 5.9 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Metallophos PF00149.28 EAX99581.1 - 2.3e-07 31.5 1.3 4.8e-07 30.5 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 EAX99582.1 - 2.3e-26 92.2 0.7 2.4e-14 53.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99582.1 - 5.3e-25 87.2 0.7 2.3e-09 37.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99582.1 - 5.4e-24 84.2 1.5 1.4e-07 31.9 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99582.1 - 5.1e-22 77.3 1.0 3.6e-06 27.2 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAX99582.1 - 4.9e-17 60.3 1.2 0.0083 16.6 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat WWE PF02825.20 EAX99583.1 - 0.4 11.3 5.7 9.6 6.9 2.2 3.6 1 1 1 2 2 2 0 WWE domain AdoMet_dc PF02675.15 EAX99583.1 - 1.6 9.0 22.5 2.9 8.2 7.4 4.4 1 1 3 4 4 4 0 S-adenosylmethionine decarboxylase Ank_2 PF12796.7 EAX99585.1 - 5e-06 27.0 0.3 9.8e-06 26.1 0.3 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99585.1 - 5e-05 23.5 0.2 8.7e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99585.1 - 8.2e-05 22.7 0.0 0.075 13.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAX99585.1 - 0.00034 21.1 0.2 0.02 15.5 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99585.1 - 0.0057 17.1 0.0 0.81 10.2 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat DUF4201 PF13870.6 EAX99586.1 - 0.0047 16.7 2.4 0.0047 16.7 2.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) PAH PF02671.21 EAX99586.1 - 0.0082 16.3 3.6 0.0082 16.3 3.6 1.9 2 1 0 2 2 2 1 Paired amphipathic helix repeat DUF2321 PF10083.9 EAX99586.1 - 0.029 14.0 0.5 0.029 14.0 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) bZIP_1 PF00170.21 EAX99586.1 - 0.029 14.5 4.6 0.029 14.5 4.6 2.1 2 0 0 2 2 2 0 bZIP transcription factor RcsC PF09456.10 EAX99586.1 - 0.036 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Imm3 PF14425.6 EAX99586.1 - 0.41 10.7 4.5 2.8 8.0 0.4 2.4 2 1 0 2 2 2 0 Immunity protein Imm3 Syntaxin PF00804.25 EAX99586.1 - 0.96 9.1 8.7 2.4 7.8 8.7 1.6 1 1 0 1 1 1 0 Syntaxin HALZ PF02183.18 EAX99586.1 - 1.5 9.1 7.5 0.22 11.8 3.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-H PF05837.12 EAX99586.1 - 2.2 8.7 6.4 0.46 10.9 1.6 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) AAA_12 PF13087.6 EAX99587.1 - 2e-26 92.9 0.8 2e-26 92.9 0.8 3.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EAX99587.1 - 4.7e-10 39.7 1.2 4.7e-10 39.7 1.2 3.5 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAX99587.1 - 3e-07 30.9 0.0 7.2e-06 26.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAX99587.1 - 2.1e-06 27.7 1.4 0.0017 18.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EAX99587.1 - 0.0016 17.9 0.0 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 EAX99587.1 - 0.0027 17.4 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Terminase_GpA PF05876.12 EAX99587.1 - 0.014 14.0 0.3 0.028 13.0 0.0 1.6 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) DUF2075 PF09848.9 EAX99587.1 - 0.035 13.4 0.0 0.093 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EAX99587.1 - 0.04 13.9 0.1 0.04 13.9 0.1 4.2 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit ATPase PF06745.13 EAX99587.1 - 0.17 11.2 1.6 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 KaiC UvrD_C_2 PF13538.6 EAX99587.1 - 0.22 11.4 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pkinase PF00069.25 EAX99588.1 - 3.5e-32 111.8 0.0 4.2e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99588.1 - 4.2e-17 62.3 0.0 7.2e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase ABC_tran PF00005.27 EAX99589.1 - 7.5e-43 146.3 0.0 2.8e-23 82.9 0.0 3.1 2 1 1 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EAX99589.1 - 2.1e-17 62.9 0.7 5e-17 61.7 0.7 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAX99589.1 - 1e-08 34.9 2.1 0.014 14.8 0.0 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAX99589.1 - 3.4e-08 33.7 7.1 0.12 12.2 1.8 4.7 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAX99589.1 - 4.3e-06 27.4 4.2 0.025 15.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EAX99589.1 - 3e-05 23.7 0.1 0.012 15.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAX99589.1 - 0.00016 21.7 0.1 0.076 13.1 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX99589.1 - 0.00018 21.8 0.0 0.53 10.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EAX99589.1 - 0.00041 20.2 11.9 0.11 12.2 0.6 4.1 3 1 1 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 EAX99589.1 - 0.0006 19.8 3.5 0.022 14.6 0.1 2.8 3 0 0 3 3 2 1 RsgA GTPase NACHT PF05729.12 EAX99589.1 - 0.0011 19.0 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain PRK PF00485.18 EAX99589.1 - 0.0012 18.7 0.1 3.9 7.2 0.1 3.3 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EAX99589.1 - 0.002 18.1 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EAX99589.1 - 0.0027 17.5 3.1 0.43 10.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EAX99589.1 - 0.0031 17.9 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EAX99589.1 - 0.0051 17.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 EAX99589.1 - 0.0081 16.4 0.1 2.5 8.4 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EAX99589.1 - 0.0087 16.2 0.1 1.7 8.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EAX99589.1 - 0.0089 16.1 0.1 0.1 12.6 0.0 2.7 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.17 EAX99589.1 - 0.015 15.4 4.7 5.1 7.1 0.0 3.9 5 0 0 5 5 5 0 Helicase HerA, central domain AAA_28 PF13521.6 EAX99589.1 - 0.015 15.5 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EAX99589.1 - 0.018 14.5 0.2 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein Thymidylate_kin PF02223.17 EAX99589.1 - 0.019 14.7 0.0 9.3 5.9 0.1 3.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 EAX99589.1 - 0.025 14.3 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EAX99589.1 - 0.026 13.8 0.4 4.8 6.4 0.1 2.8 2 1 1 3 3 3 0 Septin MeaB PF03308.16 EAX99589.1 - 0.028 13.4 0.0 0.89 8.5 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EAX99589.1 - 0.029 14.6 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EAX99589.1 - 0.038 13.5 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EAX99589.1 - 0.04 13.0 0.1 0.6 9.1 0.1 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EAX99589.1 - 0.042 13.2 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 EAX99589.1 - 0.047 12.9 0.3 3.5 6.7 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EAX99589.1 - 0.059 12.5 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EAX99589.1 - 0.063 13.6 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAX99589.1 - 0.068 13.7 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAX99589.1 - 0.077 13.4 0.1 38 4.7 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) LRR_4 PF12799.7 EAX99590.1 - 1.5e-16 60.2 26.3 9.3e-05 22.7 0.7 7.3 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX99590.1 - 2e-08 33.8 18.7 0.00072 19.3 0.4 5.4 3 1 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EAX99590.1 - 0.021 14.8 12.9 2.1 8.6 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat DivIC PF04977.15 EAX99590.1 - 0.33 10.7 6.2 1 9.2 4.1 3.0 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 EAX99590.1 - 2.2 8.6 5.4 6 7.2 0.0 3.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper Sld5 PF05916.11 EAX99591.1 - 0.071 13.6 0.1 0.09 13.2 0.1 1.4 1 0 0 1 1 1 0 GINS complex protein IBD PF10416.9 EAX99592.1 - 2.2e-48 163.5 3.1 2.6e-48 163.3 3.1 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD IL15 PF02372.15 EAX99592.1 - 0.064 13.3 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Interleukin 15 DUF4108 PF13390.6 EAX99593.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAX99594.1 - 1.4 8.9 5.9 2.9 7.9 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pox_A32 PF04665.12 EAX99595.1 - 5.4e-07 29.3 2.3 5.4e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99595.1 - 1.9e-05 24.9 0.2 0.00014 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99595.1 - 4.5e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99595.1 - 0.00011 22.2 3.8 0.00029 20.9 3.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAX99595.1 - 0.00039 20.3 0.6 0.0008 19.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAX99595.1 - 0.00041 20.1 0.1 0.00075 19.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zot PF05707.12 EAX99595.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99595.1 - 0.009 16.3 0.0 0.018 15.4 0.0 1.7 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EAX99595.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAX99595.1 - 0.18 11.4 0.0 0.59 9.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAX99595.1 - 0.49 10.7 4.4 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAX99596.1 - 9.9e-40 134.9 0.4 2.1e-39 133.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX99596.1 - 0.032 14.4 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF3839 PF12943.7 EAX99597.1 - 6e-80 268.2 10.0 7.9e-80 267.8 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAX99597.1 - 0.041 14.5 0.4 0.068 13.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1493 PF07377.12 EAX99598.1 - 0.057 13.9 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99599.1 - 0.26 12.0 6.4 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99600.1 - 0.11 12.4 1.3 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 PSP Myb_DNA-binding PF00249.31 EAX99601.1 - 5.4e-21 74.5 4.8 3.2e-10 40.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99601.1 - 1.9e-16 60.1 2.5 3e-08 33.8 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAX99601.1 - 0.0015 18.8 2.3 0.056 13.8 0.3 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 EAX99601.1 - 0.0089 16.4 4.9 0.79 10.1 0.9 2.5 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Endonuc-PvuII PF09225.10 EAX99601.1 - 0.13 12.0 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII Myosin_TH1 PF06017.13 EAX99602.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding DUF4119 PF13494.6 EAX99603.1 - 0.037 14.2 1.1 0.056 13.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF2312 PF10073.9 EAX99603.1 - 0.078 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1911 PF08929.10 EAX99603.1 - 0.11 13.3 0.2 0.15 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) DUF4457 PF14652.6 EAX99604.1 - 7.1e-05 22.2 0.1 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4457) Pox_A32 PF04665.12 EAX99605.1 - 4.5e-05 23.0 3.8 7e-05 22.4 3.8 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX99605.1 - 0.0022 18.0 1.6 0.0031 17.5 0.3 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX99605.1 - 0.012 15.2 0.4 0.024 14.2 0.4 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX99605.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAX99605.1 - 0.048 14.0 1.9 0.11 12.8 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) IF4E PF01652.18 EAX99609.1 - 1.3e-34 119.3 0.0 1.6e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E P3A PF08727.11 EAX99609.1 - 0.028 13.8 0.3 0.051 13.0 0.3 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like LRR_6 PF13516.6 EAX99610.1 - 2.1e-15 55.4 43.0 0.00028 20.7 0.3 12.8 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 EAX99610.1 - 1.3e-07 31.8 41.8 0.044 14.2 4.0 8.3 7 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX99610.1 - 0.008 15.9 37.3 1.2 8.9 0.8 8.5 4 3 4 8 8 8 4 Leucine rich repeat LRR_1 PF00560.33 EAX99610.1 - 0.042 14.4 25.7 11 7.1 0.1 9.0 8 2 0 8 8 8 0 Leucine Rich Repeat Cytomega_UL84 PF06284.11 EAX99610.1 - 3.1 6.2 9.1 5.3 5.4 9.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DAGK_acc PF00609.19 EAX99612.1 - 1.1e-36 126.6 0.0 1.7e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EAX99612.1 - 2e-18 66.2 0.0 3.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Abi_2 PF07751.11 EAX99613.1 - 0.0031 17.8 0.4 0.014 15.7 0.1 2.3 2 0 0 2 2 2 1 Abi-like protein Cnd1 PF12717.7 EAX99613.1 - 0.005 16.9 2.5 0.024 14.7 1.9 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EAX99613.1 - 0.018 15.2 0.2 0.32 11.2 0.1 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EAX99613.1 - 0.027 14.5 2.9 0.34 10.9 0.2 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central UME PF08064.13 EAX99613.1 - 0.86 9.5 5.0 43 4.1 0.1 4.7 5 1 1 6 6 6 0 UME (NUC010) domain MULE PF10551.9 EAX99615.1 - 2.8e-10 40.5 2.9 5.3e-10 39.6 1.5 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAX99615.1 - 0.0019 17.1 0.2 0.0033 16.3 0.2 1.3 1 0 0 1 1 1 1 Transposase, Mutator family CIDR1_gamma PF18562.1 EAX99615.1 - 0.0021 18.1 1.1 0.0067 16.5 1.1 1.9 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma ubiquitin PF00240.23 EAX99616.1 - 8.2e-06 25.5 0.0 2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX99616.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAX99616.1 - 0.049 14.0 0.0 0.46 10.9 0.0 2.3 1 1 2 3 3 3 0 Ubiquitin-like domain Homeobox_KN PF05920.11 EAX99617.1 - 3.2e-16 58.9 0.9 6.4e-16 58.0 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAX99617.1 - 2.2e-11 43.4 0.5 3.7e-11 42.7 0.5 1.3 1 0 0 1 1 1 1 Homeodomain HTH_26 PF13443.6 EAX99617.1 - 0.061 13.8 0.0 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Raf1_HTH PF18579.1 EAX99617.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Ank_4 PF13637.6 EAX99618.1 - 5e-18 65.2 0.6 1.7e-10 41.2 0.1 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99618.1 - 1.2e-17 63.8 0.4 3e-10 40.1 0.0 3.2 1 1 3 4 4 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99618.1 - 4.8e-17 62.3 0.9 3.2e-11 43.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99618.1 - 9.5e-14 50.2 0.2 0.0042 17.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAX99618.1 - 6.1e-06 26.4 0.2 0.019 15.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat bZIP_1 PF00170.21 EAX99618.1 - 0.00045 20.3 3.0 0.0012 18.9 3.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor RasGAP_C PF03836.15 EAX99618.1 - 0.0017 18.5 2.9 0.0017 18.5 2.9 1.9 2 0 0 2 2 1 1 RasGAP C-terminus DivIC PF04977.15 EAX99618.1 - 0.0047 16.7 0.9 0.01 15.6 0.9 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF5082 PF16888.5 EAX99618.1 - 0.0058 16.9 1.3 0.013 15.8 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Retrotrans_gag PF03732.17 EAX99618.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4686 PF15742.5 EAX99618.1 - 0.011 14.9 2.2 0.015 14.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) YabA PF06156.13 EAX99618.1 - 0.016 15.8 0.6 0.036 14.7 0.6 1.6 1 0 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 EAX99618.1 - 0.022 13.4 5.1 0.026 13.2 4.2 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A T4_tail_cap PF11091.8 EAX99618.1 - 0.024 13.6 0.2 0.038 12.9 0.2 1.2 1 0 0 1 1 1 0 Tail-tube assembly protein Herpes_UL6 PF01763.16 EAX99618.1 - 0.029 12.9 0.5 0.038 12.5 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Syntaxin-6_N PF09177.11 EAX99618.1 - 0.043 14.4 0.2 0.1 13.2 0.2 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF641 PF04859.12 EAX99618.1 - 0.043 14.1 0.4 0.087 13.2 0.4 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 EAX99618.1 - 0.048 14.1 0.6 0.07 13.6 0.6 1.2 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 EAX99618.1 - 0.051 13.6 2.6 0.1 12.6 2.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 EAX99618.1 - 0.059 13.7 2.3 0.19 12.1 2.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Atg14 PF10186.9 EAX99618.1 - 0.06 12.4 2.2 0.079 12.0 2.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3349 PF11829.8 EAX99618.1 - 0.081 13.7 0.1 0.45 11.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) FlaC_arch PF05377.11 EAX99618.1 - 0.086 13.3 6.0 0.064 13.7 3.5 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Mitofilin PF09731.9 EAX99618.1 - 0.088 11.6 3.5 0.12 11.2 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoLp-III PF07464.11 EAX99618.1 - 0.11 12.6 4.9 0.51 10.4 4.8 2.1 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Med30 PF11315.8 EAX99618.1 - 0.11 12.7 4.9 8.8 6.5 0.0 2.4 2 1 0 2 2 2 0 Mediator complex subunit 30 DUF465 PF04325.13 EAX99618.1 - 0.12 12.4 1.4 0.32 11.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) ZapB PF06005.12 EAX99618.1 - 0.12 12.8 4.1 0.29 11.6 4.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF3837 PF12939.7 EAX99618.1 - 0.12 12.8 8.6 1.1 9.6 0.3 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF3837) DUF4200 PF13863.6 EAX99618.1 - 0.14 12.6 5.1 0.058 13.8 2.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DUF4988 PF16378.5 EAX99618.1 - 0.16 11.6 2.0 0.86 9.3 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function MCC-bdg_PDZ PF10506.9 EAX99618.1 - 0.33 11.0 2.7 0.33 11.0 0.6 2.1 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DED PF01335.21 EAX99618.1 - 0.39 11.1 5.6 0.11 12.9 0.9 2.5 3 0 0 3 3 2 0 Death effector domain SF3A3 PF16837.5 EAX99618.1 - 0.54 10.8 4.8 17 6.0 1.6 3.2 3 1 0 3 3 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Tropomyosin_1 PF12718.7 EAX99618.1 - 0.72 10.0 5.2 1.4 9.0 5.1 1.5 1 1 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 EAX99618.1 - 1.1 9.8 5.8 1.9 9.0 2.6 2.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Goodbye PF17109.5 EAX99618.1 - 1.3 9.5 6.0 1.4 9.3 1.4 2.8 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain CCDC74_C PF14917.6 EAX99618.1 - 1.8 9.1 4.8 10 6.7 2.0 2.7 2 1 1 3 3 2 0 Coiled coil protein 74, C terminal Metallophos PF00149.28 EAX99620.1 - 4.4e-34 118.8 0.0 5.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAX99620.1 - 0.02 15.1 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Endonuclease_1 PF04231.13 EAX99621.1 - 8.7e-22 77.9 0.5 2e-21 76.8 0.5 1.5 1 1 0 1 1 1 1 Endonuclease I Caskin-Pro-rich PF16907.5 EAX99622.1 - 0.023 15.2 0.4 0.023 15.2 0.4 2.4 3 0 0 3 3 3 0 Proline rich region of Caskin proteins Ureide_permease PF07168.11 EAX99622.1 - 0.73 8.5 3.0 1.4 7.6 3.0 1.4 1 0 0 1 1 1 0 Ureide permease DUF334 PF03904.13 EAX99623.1 - 5 6.6 10.5 12 5.3 1.0 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF334) HTH_37 PF13744.6 EAX99624.1 - 0.061 13.3 1.6 2.2 8.3 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain Methyltransf_FA PF12248.8 EAX99625.1 - 0.039 14.3 1.0 0.17 12.2 1.0 2.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Pkinase PF00069.25 EAX99626.1 - 3.2e-29 102.1 1.3 1.2e-28 100.2 1.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99626.1 - 1.7e-19 70.1 0.1 2.4e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99626.1 - 3.1e-06 26.7 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX99626.1 - 0.036 12.8 0.1 0.057 12.2 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C21 PF05381.12 EAX99627.1 - 0.002 18.5 0.0 0.0057 17.0 0.0 1.8 1 0 0 1 1 1 1 Tymovirus endopeptidase Pentapeptide PF00805.22 EAX99627.1 - 0.0035 17.0 0.1 1.9 8.2 0.0 3.0 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EAX99627.1 - 0.085 13.0 5.3 0.96 9.7 0.1 4.1 4 2 0 4 4 4 0 Pentapeptide repeats (9 copies) PSP PF04046.16 EAX99628.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99629.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX99631.1 - 1.6e-05 24.8 5.0 1.6e-05 24.8 5.0 5.8 5 2 1 6 6 6 2 Phage tail repeat like DUF4738 PF15889.5 EAX99631.1 - 0.019 14.8 1.9 0.019 14.8 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) DUF4116 PF13475.6 EAX99631.1 - 0.12 12.1 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAX99631.1 - 0.72 10.4 2.5 2.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAX99631.1 - 5 6.7 14.6 0.038 13.6 2.9 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4795) DUF3839 PF12943.7 EAX99632.1 - 1.2e-131 437.4 13.2 3.6e-131 435.9 13.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX99632.1 - 0.0075 16.7 0.4 0.05 14.1 0.1 2.0 2 0 0 2 2 2 1 Fez1 Rx_N PF18052.1 EAX99632.1 - 0.11 12.8 0.7 5.4 7.4 0.0 3.3 3 1 1 4 4 4 0 Rx N-terminal domain KELK PF15796.5 EAX99632.1 - 0.13 12.7 3.5 1.6 9.3 0.2 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 EAX99633.1 - 8.4e-48 160.9 0.3 1.4e-08 35.2 0.1 6.7 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99633.1 - 5.7e-31 103.1 3.3 0.0018 18.6 0.1 11.3 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.6 EAX99633.1 - 2.1e-30 104.7 2.9 8.5e-08 32.6 0.0 7.9 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99633.1 - 1.2e-27 95.6 2.1 1.2e-07 31.9 0.1 8.1 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX99633.1 - 2.1e-25 88.0 7.6 0.0001 22.6 0.3 9.1 10 1 1 11 11 11 5 Ankyrin repeat SH3-WW_linker PF16618.5 EAX99633.1 - 0.011 16.2 8.9 0.02 15.4 8.9 1.3 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 Pex14_N PF04695.13 EAX99633.1 - 0.014 16.1 8.2 0.036 14.7 8.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3788 PF12663.7 EAX99633.1 - 0.39 10.7 2.4 0.65 10.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3788) Staphylokinase PF02821.16 EAX99633.1 - 0.76 10.2 0.0 0.76 10.2 0.0 2.8 3 1 1 4 4 4 0 Staphylokinase/Streptokinase family Spt20 PF12090.8 EAX99633.1 - 0.94 9.0 15.2 1.9 8.0 15.2 1.4 1 0 0 1 1 1 0 Spt20 family STN PF07660.14 EAX99634.1 - 0.0089 15.8 1.2 0.68 9.8 0.2 2.8 2 0 0 2 2 2 2 Secretin and TonB N terminus short domain IBN_N PF03810.19 EAX99634.1 - 0.051 13.5 0.1 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Importin-beta N-terminal domain His_kinase PF06580.13 EAX99635.1 - 0.47 10.8 8.2 2.6 8.4 0.2 3.9 3 1 2 5 5 5 0 Histidine kinase NPV_P10 PF05531.12 EAX99636.1 - 0.0009 19.7 2.5 0.0021 18.5 2.4 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EAX99636.1 - 0.032 12.9 5.1 0.039 12.6 5.1 1.1 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.11 EAX99636.1 - 0.049 13.7 4.0 0.066 13.3 1.8 2.3 1 1 1 2 2 2 0 Vps51/Vps67 ALMT PF11744.8 EAX99636.1 - 0.088 11.6 1.5 0.089 11.6 1.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter IFP_35_N PF07334.13 EAX99636.1 - 0.22 11.6 8.3 0.44 10.7 8.3 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ku_C PF03730.14 EAX99636.1 - 0.82 10.4 8.2 3 8.6 7.7 2.0 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm PCRF PF03462.18 EAX99636.1 - 3.1 7.6 7.1 4.3 7.1 6.8 1.3 1 1 0 1 1 1 0 PCRF domain Flp_N PF03930.14 EAX99637.1 - 0.33 11.0 2.4 0.48 10.4 0.8 2.1 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus DUF1137 PF06587.11 EAX99638.1 - 0.019 15.0 1.2 0.076 13.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1137) DUF5123 PF17161.4 EAX99638.1 - 0.094 13.8 1.3 0.094 13.8 1.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5123) Bromodomain PF00439.25 EAX99640.1 - 2.8e-21 75.4 0.0 4.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain UQ_con PF00179.26 EAX99641.1 - 2.3e-20 72.7 0.2 7.4e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Macoilin PF09726.9 EAX99641.1 - 0.044 12.3 10.6 0.058 12.0 10.6 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 EAX99641.1 - 0.071 11.2 9.0 0.085 11.0 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3347 PF11827.8 EAX99641.1 - 0.96 9.6 9.3 1.5 9.0 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Pkinase PF00069.25 EAX99643.1 - 2.2e-48 164.9 0.1 2.8e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99643.1 - 5.3e-27 94.7 0.0 9.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99643.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAX99643.1 - 0.00018 21.2 0.4 0.00027 20.6 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EAX99643.1 - 0.00078 18.5 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EAX99643.1 - 0.0026 17.4 0.1 0.094 12.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX99643.1 - 0.045 13.7 0.2 1.2 9.0 1.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4200 PF13863.6 EAX99644.1 - 1.5e-22 80.2 13.6 1.5e-22 80.2 13.6 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4200) LAGLIDADG_1 PF00961.19 EAX99644.1 - 2.2 9.3 7.3 4.7 8.2 1.0 2.8 3 0 0 3 3 3 0 LAGLIDADG endonuclease PAS_9 PF13426.7 EAX99645.1 - 0.00041 20.6 3.2 0.0031 17.7 1.9 2.9 2 0 0 2 2 2 1 PAS domain DUF3788 PF12663.7 EAX99645.1 - 0.059 13.3 0.1 0.47 10.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) Phage_holin_2_3 PF16080.5 EAX99645.1 - 0.13 12.1 4.7 0.13 12.0 0.7 3.0 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Ank_2 PF12796.7 EAX99646.1 - 8.2e-18 64.8 0.1 1.4e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99646.1 - 4.6e-15 55.8 0.0 3.8e-09 36.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99646.1 - 2.9e-12 45.6 0.0 0.0029 17.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAX99646.1 - 4.1e-11 42.9 0.1 0.0047 17.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99646.1 - 6.2e-11 42.2 0.0 0.00064 20.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeat SnAPC_2_like PF11035.8 EAX99646.1 - 0.068 13.3 4.7 0.096 12.8 4.7 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF5069 PF16798.5 EAX99646.1 - 0.18 12.0 1.9 0.4 10.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) SPATA3 PF15662.5 EAX99646.1 - 0.62 10.7 3.5 0.83 10.2 3.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Asp-B-Hydro_N PF05279.11 EAX99646.1 - 1.9 8.5 10.1 2.8 8.0 10.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ank_2 PF12796.7 EAX99647.1 - 1e-30 106.1 0.0 1.2e-15 57.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99647.1 - 1.1e-26 92.9 0.0 8.8e-11 42.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99647.1 - 5.2e-23 80.4 0.0 1.3e-05 25.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAX99647.1 - 1.5e-22 79.3 0.0 2.9e-08 33.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99647.1 - 2.6e-19 67.3 0.0 0.00076 19.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF3083 PF11281.8 EAX99647.1 - 0.021 14.2 0.0 0.75 9.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3083) Pox_E8 PF03394.13 EAX99647.1 - 0.03 13.9 0.1 4.8 6.7 0.0 3.0 1 1 3 4 4 4 0 Poxvirus E8 protein Pkinase PF00069.25 EAX99649.1 - 6.6e-68 228.9 0.0 1.2e-67 228.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99649.1 - 5.7e-50 170.0 0.0 1.4e-49 168.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EAX99649.1 - 0.0014 18.3 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EAX99649.1 - 0.0048 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX99649.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EAX99649.1 - 0.067 13.1 0.0 4.2 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAX99649.1 - 0.13 11.6 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2379 PF09543.10 EAX99649.1 - 0.22 11.7 0.6 5.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) Ank_2 PF12796.7 EAX99650.1 - 2.2e-56 188.4 36.7 3.6e-19 69.1 4.4 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99650.1 - 9.3e-40 134.5 11.4 1.4e-12 47.9 0.1 7.7 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX99650.1 - 1.4e-38 129.6 8.5 1.2e-07 31.8 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat DUF3447 PF11929.8 EAX99650.1 - 1.8e-36 123.9 8.1 1.8e-36 123.9 8.1 3.2 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX99650.1 - 4.3e-30 103.4 12.5 1.7e-10 40.9 0.6 6.3 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99650.1 - 2.5e-27 91.9 11.2 0.00017 21.8 0.0 8.6 8 1 1 9 9 9 5 Ankyrin repeat CdhD PF03599.16 EAX99650.1 - 0.0018 17.1 0.1 0.12 11.1 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase/acetyl-CoA synthase delta subunit YkuD_2 PF13645.6 EAX99650.1 - 0.2 11.1 2.7 5 6.6 0.2 3.0 2 1 0 3 3 3 0 L,D-transpeptidase catalytic domain Glyco_hydro_53 PF07745.13 EAX99650.1 - 0.55 9.2 5.9 0.54 9.2 1.0 2.8 1 1 2 3 3 3 0 Glycosyl hydrolase family 53 RL PF17797.1 EAX99650.1 - 0.68 9.9 4.5 3.2 7.7 0.0 3.7 4 0 0 4 4 4 0 RL domain SAB PF04382.13 EAX99650.1 - 2.6 8.2 4.2 1.6e+02 2.5 0.1 4.0 4 0 0 4 4 4 0 SAB domain EF-hand_7 PF13499.6 EAX99651.1 - 3.8e-12 46.5 12.5 1.4e-07 31.8 1.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAX99651.1 - 3.9e-10 38.6 6.7 0.0079 15.7 1.4 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EAX99651.1 - 9.2e-08 31.4 4.4 0.0077 16.1 1.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EAX99651.1 - 5.8e-07 28.7 6.5 0.039 13.4 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EAX99651.1 - 6.5e-07 29.1 9.1 0.024 14.5 0.9 3.6 3 1 1 4 4 4 3 EF-hand domain pair InvH PF04741.12 EAX99651.1 - 0.059 13.3 0.0 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 InvH outer membrane lipoprotein EF-hand_4 PF12763.7 EAX99651.1 - 0.11 12.4 0.5 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF829 PF05705.14 EAX99652.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) XPG_I PF00867.18 EAX99652.1 - 0.13 12.6 0.8 44 4.5 0.1 3.3 1 1 2 3 3 3 0 XPG I-region Cnd1 PF12717.7 EAX99652.1 - 0.31 11.1 6.1 0.66 10.0 2.6 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 F420_oxidored PF03807.17 EAX99653.1 - 9.6e-10 38.9 0.0 1.7e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EAX99653.1 - 0.00038 20.7 0.1 0.0021 18.3 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EAX99653.1 - 0.069 13.4 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain LRR_9 PF14580.6 EAX99654.1 - 0.00067 19.2 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EAX99654.1 - 0.077 13.4 2.8 0.26 11.7 2.8 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) PSP PF04046.16 EAX99655.1 - 0.072 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99656.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DDR PF08841.10 EAX99659.1 - 0.11 11.4 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FAS_N PF17828.1 EAX99661.1 - 0.0072 16.3 0.2 0.0095 15.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta PapD_N PF00345.20 EAX99662.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAX99663.1 - 5.2e-23 81.7 8.4 5.7e-22 78.2 7.9 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX99663.1 - 0.2 11.2 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3839 PF12943.7 EAX99664.1 - 5.8e-153 507.2 13.8 7.3e-153 506.9 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99664.1 - 0.091 13.2 2.5 1.8 9.1 0.1 2.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX99664.1 - 0.34 11.2 3.6 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Tup N-terminal Amidase02_C PF12123.8 EAX99665.1 - 0.0084 15.8 0.1 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX99667.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAX99667.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase DNA_pol_B_2 PF03175.13 EAX99668.1 - 3e-10 39.6 3.0 1.8e-09 37.0 3.0 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX99668.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 PapD_N PF00345.20 EAX99669.1 - 0.04 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX99669.1 - 0.062 13.3 0.2 0.079 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAX99670.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX99670.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_A32 PF04665.12 EAX99671.1 - 4.9e-07 29.5 2.7 4.9e-07 29.5 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAX99671.1 - 4.1e-05 23.4 0.2 0.32 10.7 0.1 2.6 1 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAX99671.1 - 9e-05 22.8 0.2 0.00057 20.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAX99671.1 - 0.00012 22.1 3.6 0.00028 20.9 3.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99671.1 - 0.00053 19.8 0.1 0.00097 19.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX99671.1 - 0.002 18.0 0.8 0.004 17.0 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX99671.1 - 0.0029 17.3 0.5 0.019 14.6 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99671.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAX99671.1 - 0.049 13.1 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAX99671.1 - 0.068 12.7 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4588 PF15251.6 EAX99671.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PhoH PF02562.16 EAX99671.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX99671.1 - 0.11 12.9 0.1 0.73 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX99671.1 - 0.24 11.7 4.3 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) NMT PF01233.19 EAX99672.1 - 0.067 13.0 0.9 0.1 12.4 0.7 1.4 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4108 PF13390.6 EAX99673.1 - 1.2e-62 210.0 6.1 1.4e-62 209.9 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAX99674.1 - 1.2e-05 25.7 0.5 2.2e-05 24.9 0.5 1.5 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAX99674.1 - 0.0029 18.2 0.1 0.0038 17.8 0.1 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EAX99674.1 - 0.009 16.0 0.2 0.012 15.5 0.2 1.3 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain Ank_2 PF12796.7 EAX99675.1 - 1.4e-27 96.0 2.1 1.8e-15 57.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99675.1 - 1.2e-14 53.9 0.0 0.00017 21.8 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAX99675.1 - 2.5e-13 48.9 0.0 0.00059 20.1 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAX99675.1 - 2.6e-13 50.2 0.0 2.2e-06 28.1 0.0 4.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99675.1 - 7.8e-13 48.4 0.0 1e-09 38.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Peroxin-3 PF04882.12 EAX99675.1 - 0.011 14.8 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF1882 PF08966.11 EAX99675.1 - 0.25 11.6 3.9 0.44 10.8 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1882) Phage_holin_5_2 PF16079.5 EAX99676.1 - 0.014 15.7 7.2 0.042 14.2 1.5 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V YIF1 PF03878.15 EAX99676.1 - 6.3 6.2 17.6 0.023 14.2 3.2 2.7 1 1 1 3 3 3 0 YIF1 Pkinase PF00069.25 EAX99677.1 - 1.9e-31 109.4 0.0 2.6e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99677.1 - 1e-15 57.8 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99677.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TMEM154 PF15102.6 EAX99678.1 - 0.00037 20.4 0.7 0.00088 19.2 0.7 1.7 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 EAX99678.1 - 0.003 17.7 2.3 0.0055 16.8 2.3 1.4 1 0 0 1 1 1 1 Podoplanin DUF2370 PF10176.9 EAX99678.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Glycophorin_A PF01102.18 EAX99678.1 - 0.034 14.4 0.5 0.24 11.7 0.1 2.5 2 0 0 2 2 2 0 Glycophorin A DAG1 PF05454.11 EAX99678.1 - 0.035 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1180 PF06679.12 EAX99678.1 - 0.14 12.5 2.9 0.25 11.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M56 PF05569.11 EAX99678.1 - 0.22 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 RhoGAP PF00620.27 EAX99679.1 - 5.4e-19 68.5 0.0 9.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_S2 PF00318.20 EAX99681.1 - 0.0035 16.6 0.0 0.085 12.1 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Gag_p19 PF02228.16 EAX99681.1 - 0.11 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Major core protein p19 Gly_rich PF12810.7 EAX99683.1 - 6.7e-23 81.9 26.5 7.8e-23 81.6 26.5 1.0 1 0 0 1 1 1 1 Glycine rich protein PXA PF02194.15 EAX99684.1 - 0.023 14.7 0.1 0.093 12.7 0.1 2.1 1 1 0 1 1 1 0 PXA domain DUF3477 PF11963.8 EAX99684.1 - 0.15 11.2 0.7 0.3 10.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) TFIIS_M PF07500.14 EAX99684.1 - 0.33 11.5 5.4 2.2 8.8 0.0 3.8 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS), central domain PTR PF12789.7 EAX99685.1 - 1.9e-27 95.1 13.2 1.9e-27 95.1 13.2 2.6 3 0 0 3 3 3 1 Phage tail repeat like Myb_DNA-binding PF00249.31 EAX99686.1 - 2.1e-24 85.4 1.3 1.8e-15 56.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99686.1 - 8.9e-18 64.3 4.9 4.6e-14 52.4 0.5 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAX99686.1 - 0.003 17.6 1.9 0.1 12.7 0.0 2.6 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAX99686.1 - 0.006 16.5 1.9 0.21 11.5 0.2 2.5 2 1 0 2 2 2 1 Myb DNA-binding like FragX_IP PF05994.11 EAX99686.1 - 0.056 11.5 0.1 0.073 11.1 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Pkinase PF00069.25 EAX99687.1 - 6.1e-64 215.9 0.0 7.4e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99687.1 - 4.3e-40 137.6 0.0 5.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAX99687.1 - 0.0003 19.7 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAX99687.1 - 0.0025 17.2 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAX99687.1 - 0.12 12.0 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAX99687.1 - 0.13 12.2 0.0 0.41 10.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 EAX99688.1 - 1.2e-15 57.8 0.4 1.2e-13 51.4 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99688.1 - 3.7e-13 49.7 4.6 4.7e-05 23.9 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99688.1 - 1.1e-10 41.6 0.3 9.5e-06 25.8 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99688.1 - 4.6e-07 29.6 0.1 0.24 12.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat OSTMP1 PF09777.9 EAX99688.1 - 0.017 14.5 0.1 0.033 13.6 0.0 1.5 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Ank PF00023.30 EAX99688.1 - 0.02 15.4 0.1 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat HMG_box_2 PF09011.10 EAX99689.1 - 0.0036 17.9 0.9 0.0081 16.7 0.9 1.7 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EAX99689.1 - 0.004 17.5 1.0 0.024 15.0 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box DUF3106 PF11304.8 EAX99689.1 - 0.031 14.7 0.8 0.28 11.7 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) ANAPC4_WD40 PF12894.7 EAX99690.1 - 4.7e-08 33.2 0.0 0.68 10.3 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAX99690.1 - 0.0002 22.1 1.1 48 5.1 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat eIF2A PF08662.11 EAX99690.1 - 0.0013 18.6 0.2 0.012 15.5 0.1 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EAX99690.1 - 0.0023 17.6 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain RAB3GAP2_N PF14655.6 EAX99690.1 - 0.0078 15.5 0.5 1.4 8.1 0.1 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS1 PF14779.6 EAX99690.1 - 0.038 13.4 0.2 2.2 7.7 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 1 MT-A70 PF05063.14 EAX99690.1 - 0.17 11.8 0.7 0.39 10.6 0.7 1.6 1 0 0 1 1 1 0 MT-A70 EF-hand_7 PF13499.6 EAX99691.1 - 5.6e-17 62.0 3.7 6.6e-08 32.9 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX99691.1 - 1.4e-15 55.8 3.0 0.00013 21.6 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EAX99691.1 - 2.4e-12 45.4 11.5 0.00019 20.8 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EAX99691.1 - 8.2e-10 38.4 3.7 1e-06 28.5 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EAX99691.1 - 2.2e-09 36.4 7.0 0.00086 18.7 0.1 4.4 4 0 0 4 4 4 2 EF hand ubiquitin PF00240.23 EAX99692.1 - 0.00011 21.8 0.5 0.00032 20.4 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAX99692.1 - 0.0012 18.6 2.6 0.0012 18.6 2.6 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Beach PF02138.18 EAX99693.1 - 1.1e-91 307.1 0.3 2.1e-91 306.1 0.3 1.5 1 0 0 1 1 1 1 Beige/BEACH domain ATP_bind_3 PF01171.20 EAX99693.1 - 0.12 12.1 0.4 24 4.6 0.1 2.8 3 0 0 3 3 3 0 PP-loop family S6OS1 PF15676.5 EAX99694.1 - 0.001 17.6 1.0 0.0016 17.0 1.0 1.2 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family DUF3928 PF13065.6 EAX99694.1 - 2.2 9.1 5.9 4.3 8.2 3.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3928) RGS PF00615.19 EAX99695.1 - 9 6.6 10.8 0.41 10.9 0.4 3.7 3 0 0 3 3 3 0 Regulator of G protein signaling domain DUF563 PF04577.14 EAX99696.1 - 2.9e-31 109.2 2.9 3.8e-31 108.9 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ank_2 PF12796.7 EAX99697.1 - 2.3e-29 101.8 1.1 1.1e-15 57.9 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99697.1 - 1.6e-22 79.6 1.2 2.5e-10 40.6 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99697.1 - 2.4e-21 75.5 0.3 1e-06 28.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAX99697.1 - 9.5e-19 67.0 0.0 1.1e-05 25.7 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAX99697.1 - 1.6e-15 55.7 0.1 0.00078 19.7 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat LRR_5 PF13306.6 EAX99698.1 - 1.3e-68 228.8 50.9 3e-21 75.7 4.8 6.3 3 1 2 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99698.1 - 7.5e-11 41.6 4.9 0.29 10.9 0.0 7.7 3 2 5 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAX99698.1 - 1.2e-05 25.5 9.4 0.35 11.3 0.0 6.4 5 3 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX99698.1 - 1.6 9.6 3.7 9.2 7.3 0.3 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_5 PF13306.6 EAX99699.1 - 2.7e-85 282.8 64.8 2.5e-20 72.8 8.6 7.2 3 2 2 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99699.1 - 7.2e-16 57.7 0.0 0.0013 18.4 0.0 8.7 7 1 0 8 8 8 3 Leucine rich repeat LRR_4 PF12799.7 EAX99699.1 - 2.8e-10 40.3 7.8 0.0053 17.2 0.1 7.4 8 0 0 8 8 8 3 Leucine Rich repeats (2 copies) SPX PF03105.19 EAX99699.1 - 0.00017 21.6 19.3 0.00026 21.1 19.3 1.2 1 0 0 1 1 1 1 SPX domain DUF4577 PF15145.6 EAX99699.1 - 0.023 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) LAP1C PF05609.12 EAX99699.1 - 0.026 13.6 10.2 0.04 13.0 10.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 EAX99699.1 - 0.042 12.6 17.0 0.068 11.9 17.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EAX99699.1 - 0.06 12.5 23.6 0.09 12.0 23.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Orf78 PF06024.12 EAX99699.1 - 0.068 13.5 1.8 0.1 12.9 0.1 2.0 1 1 0 2 2 2 0 Orf78 (ac78) Utp14 PF04615.13 EAX99699.1 - 0.072 11.7 11.0 0.098 11.2 11.0 1.1 1 0 0 1 1 1 0 Utp14 protein ORC6 PF05460.13 EAX99699.1 - 0.22 10.7 26.1 0.36 10.0 26.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Asp-B-Hydro_N PF05279.11 EAX99699.1 - 0.24 11.5 8.9 0.33 11.0 8.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hamartin PF04388.12 EAX99699.1 - 0.74 8.4 22.1 1.1 7.9 22.1 1.1 1 0 0 1 1 1 0 Hamartin protein PARM PF17061.5 EAX99699.1 - 1.1 9.4 32.4 2.1 8.4 32.4 1.4 1 0 0 1 1 1 0 PARM LRR_1 PF00560.33 EAX99699.1 - 1.6 9.6 8.5 14 6.7 0.1 5.4 5 0 0 5 5 3 0 Leucine Rich Repeat Apt1 PF10351.9 EAX99699.1 - 2.1 7.1 15.3 3.2 6.5 15.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_6 PF13516.6 EAX99699.1 - 8.2 6.8 12.1 7.8 6.8 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Ank_2 PF12796.7 EAX99700.1 - 6.3e-52 174.1 6.0 1.8e-18 66.9 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99700.1 - 5.5e-29 99.9 1.4 1.7e-07 31.4 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99700.1 - 3.7e-28 97.5 2.4 1.2e-09 38.5 0.1 4.5 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99700.1 - 5.9e-27 92.9 0.1 3.6e-06 27.2 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX99700.1 - 6.9e-23 78.3 0.1 0.0029 18.0 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat NDT80_PhoG PF05224.12 EAX99700.1 - 0.12 12.6 0.2 1.8 8.8 0.1 2.1 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family Vps26 PF03643.15 EAX99701.1 - 2.5e-20 72.7 0.4 3.1e-20 72.3 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EAX99701.1 - 0.0097 16.0 0.7 8.6 6.4 0.0 3.2 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 EAX99701.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D AAA_14 PF13173.6 EAX99702.1 - 0.013 15.5 0.2 0.11 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EAX99702.1 - 0.033 14.2 0.1 0.44 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EAX99702.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Anticodon_1 PF08264.13 EAX99703.1 - 0.027 14.4 0.2 0.37 10.7 0.0 2.9 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA PSP PF04046.16 EAX99704.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAX99705.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAX99707.1 - 1.9e-55 184.8 33.3 8.2e-33 112.3 16.2 5.7 4 2 2 6 6 6 3 Phage tail repeat like DUF4116 PF13475.6 EAX99707.1 - 0.035 13.8 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAX99708.1 - 1.4e-120 401.2 10.6 1.8e-120 400.9 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99708.1 - 0.009 16.4 1.7 1.8 9.0 0.0 3.1 2 1 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAX99709.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAX99709.1 - 3.2e-05 24.2 0.2 0.00023 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99709.1 - 4.9e-05 23.1 0.2 0.33 10.7 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99709.1 - 0.00014 21.9 3.1 0.00035 20.6 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99709.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAX99709.1 - 0.0012 18.6 0.6 0.0023 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX99709.1 - 0.0018 18.0 0.4 0.014 15.0 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99709.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAX99709.1 - 0.072 12.7 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAX99709.1 - 0.087 13.2 0.1 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAX99709.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAX99709.1 - 0.39 11.0 3.9 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) Rod_C PF10493.9 EAX99710.1 - 1.1e-16 60.4 10.7 1.1e-16 60.4 10.7 2.2 3 0 0 3 3 3 1 Rough deal protein C-terminal region Pkinase PF00069.25 EAX99711.1 - 4.8e-08 32.7 0.1 0.0017 17.8 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99711.1 - 0.0023 17.3 0.1 0.63 9.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase JAB PF01398.21 EAX99712.1 - 8.4e-19 67.7 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EAX99712.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CSN5_C PF18323.1 EAX99712.1 - 0.091 13.7 0.1 2.4 9.1 0.0 2.4 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Ank_4 PF13637.6 EAX99713.1 - 7.9e-44 147.5 13.8 2e-12 47.4 0.3 7.9 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99713.1 - 1.8e-35 121.3 19.4 1.9e-11 44.4 1.5 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX99713.1 - 6e-33 112.6 6.0 6e-33 112.6 6.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAX99713.1 - 1.3e-29 101.3 11.3 6.2e-06 26.4 0.0 7.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 EAX99713.1 - 5.6e-27 90.8 12.6 1.6e-05 24.9 0.1 8.2 8 1 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAX99713.1 - 1.4e-24 85.8 12.5 5.5e-10 39.3 0.6 5.4 3 2 3 6 6 6 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99714.1 - 1.2e-35 121.3 6.8 1.2e-35 121.3 6.8 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99714.1 - 1.2e-10 41.8 0.2 0.0009 19.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99714.1 - 9.8e-07 28.6 1.7 0.016 15.7 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EAX99714.1 - 7.4e-06 26.4 2.9 0.37 11.4 0.0 5.3 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99714.1 - 0.00048 20.4 0.8 0.37 11.3 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAX99714.1 - 0.0063 16.8 0.7 0.79 10.1 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAX99715.1 - 2.9e-27 93.9 1.1 7.3e-08 32.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EAX99715.1 - 3e-26 91.4 1.1 4.5e-11 43.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99715.1 - 6.1e-26 90.8 3.1 1.7e-17 63.8 1.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99715.1 - 3e-23 81.6 4.4 1.7e-09 37.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99715.1 - 1.9e-22 76.9 1.1 2.4e-05 24.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat PAZ_siRNAbind PF12212.8 EAX99715.1 - 0.00065 19.5 2.2 0.11 12.4 0.3 2.6 1 1 2 3 3 3 2 PAZ domain Arg_repressor PF01316.21 EAX99715.1 - 0.044 13.5 0.7 32 4.4 0.0 3.4 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain DUF5104 PF17117.5 EAX99715.1 - 0.044 14.2 0.3 0.084 13.3 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5104) Shigella_OspC PF06128.11 EAX99715.1 - 0.053 13.2 1.9 6.5 6.4 0.1 3.3 1 1 2 3 3 3 0 Shigella flexneri OspC protein MAF_flag10 PF01973.18 EAX99715.1 - 0.06 13.1 0.3 0.3 10.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF115 Nuc_sug_transp PF04142.15 EAX99717.1 - 6.6e-05 22.2 1.2 0.00012 21.4 1.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EAX99717.1 - 0.0084 16.3 12.9 0.0084 16.3 12.9 3.4 3 2 1 4 4 4 1 EamA-like transporter family CRT-like PF08627.10 EAX99717.1 - 0.12 11.2 13.5 0.017 14.1 7.4 2.1 1 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Pyrophosphatase PF00719.19 EAX99718.1 - 2.7e-47 160.5 0.0 3.8e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Imm70 PF15601.6 EAX99719.1 - 0.0019 17.8 14.6 8.4 5.9 0.1 5.2 1 1 6 7 7 7 7 Immunity protein 70 GHMP_kinases_N PF00288.26 EAX99720.1 - 5.6e-11 42.5 1.9 5.6e-11 42.5 1.9 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain FAS_N PF17828.1 EAX99724.1 - 0.011 15.8 0.3 0.015 15.3 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAX99725.1 - 0.002 18.5 0.4 0.0027 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) PTPS PF01242.19 EAX99725.1 - 0.099 12.6 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase TERB2 PF15101.6 EAX99725.1 - 1.5 8.9 5.2 1.6 8.7 5.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX99726.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAX99726.1 - 0.078 13.0 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol_B_2 PF03175.13 EAX99727.1 - 8.7e-09 34.8 1.2 1.5e-08 33.9 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAX99727.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAX99727.1 - 0.15 12.0 0.0 0.95 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor EF-hand_10 PF14788.6 EAX99728.1 - 0.0011 18.8 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 EF hand KilA-N PF04383.13 EAX99729.1 - 2.8e-32 110.9 0.6 6.4e-32 109.7 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAX99730.1 - 5.3e-146 484.5 9.0 6.6e-146 484.2 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX99730.1 - 0.055 13.9 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX99730.1 - 0.57 10.7 6.7 2.4 8.7 0.9 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4107 PF13389.6 EAX99731.1 - 4e-34 118.1 2.2 5.8e-34 117.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) GHMP_kinases_C PF08544.13 EAX99734.1 - 3.1e-12 46.7 0.0 3.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 GHMP kinases C terminal Sensor PF13796.6 EAX99735.1 - 0.12 12.5 0.6 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative sensor GalKase_gal_bdg PF10509.9 EAX99736.1 - 3.3e-19 68.2 0.0 7.1e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EAX99736.1 - 8.9e-15 54.8 0.1 1.9e-13 50.5 0.0 2.6 3 0 0 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EAX99736.1 - 1.1e-11 44.8 2.1 2.5e-11 43.6 2.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF4108 PF13390.6 EAX99739.1 - 1.3e-60 203.5 8.6 1.5e-60 203.3 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX99739.1 - 0.037 14.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAX99740.1 - 2e-05 25.0 2.6 7.9e-05 23.1 2.6 2.0 1 1 0 1 1 1 1 Poxvirus D5 protein-like DUF4049 PF13258.6 EAX99740.1 - 0.033 13.3 1.0 0.046 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RFX_DNA_binding PF02257.15 EAX99740.1 - 0.037 14.6 0.1 0.077 13.6 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAX99740.1 - 0.082 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HD PF01966.22 EAX99742.1 - 1.5e-12 47.8 0.2 2.6e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EAX99742.1 - 0.00029 20.6 0.9 0.00047 20.0 0.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TraI_2 PF07514.11 EAX99742.1 - 0.03 13.3 0.1 0.053 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative helicase HDOD PF08668.12 EAX99742.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Ras PF00071.22 EAX99745.1 - 5.8e-41 139.8 0.2 6.9e-41 139.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99745.1 - 2.4e-29 102.0 0.1 3.4e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99745.1 - 9.2e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAX99745.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAX99745.1 - 0.00044 20.3 0.0 0.00076 19.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99745.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 EAX99745.1 - 0.011 15.4 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF1203 PF06718.11 EAX99745.1 - 0.083 13.2 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Ricin_B_lectin PF00652.22 EAX99746.1 - 0.0095 16.2 0.0 0.73 10.1 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAX99746.1 - 0.017 15.8 0.0 0.7 10.7 0.0 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Pkinase PF00069.25 EAX99747.1 - 9.6e-24 84.1 0.0 1.2e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99747.1 - 2.7e-10 40.0 0.0 4.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX99747.1 - 0.00035 20.6 0.1 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX99747.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX99747.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAX99748.1 - 2.7e-71 240.1 0.5 4.2e-71 239.4 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99748.1 - 1.3e-45 155.8 0.0 1.7e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99748.1 - 1.5e-05 24.4 0.0 5.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EAX99748.1 - 0.00065 18.7 0.2 0.0011 18.0 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAX99748.1 - 0.0013 18.1 0.3 0.002 17.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAX99748.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAX99748.1 - 0.018 14.7 0.2 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 B2-adapt-app_C PF09066.10 EAX99748.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Sad1_UNC PF07738.13 EAX99749.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CENP-B_dimeris PF09026.10 EAX99749.1 - 0.27 11.7 9.7 0.67 10.4 9.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PhoU_div PF01865.16 EAX99750.1 - 0.24 10.7 2.0 0.47 9.7 0.4 2.3 2 1 1 3 3 3 0 Protein of unknown function DUF47 QLQ PF08880.11 EAX99752.1 - 0.049 13.4 1.3 0.14 12.0 1.3 1.7 1 0 0 1 1 1 0 QLQ Surfac_D-trimer PF09006.11 EAX99752.1 - 0.49 10.3 4.0 22 5.0 0.1 3.9 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF2730 PF10805.8 EAX99752.1 - 3.6 7.7 14.9 0.094 12.8 3.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Ank_2 PF12796.7 EAX99753.1 - 1.7e-13 50.9 1.2 4.5e-11 43.2 0.1 3.1 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99753.1 - 1.8e-12 47.5 0.3 3.9e-05 24.1 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99753.1 - 3.7e-07 29.9 0.7 0.52 11.0 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAX99753.1 - 1.5e-05 25.2 1.1 0.7 10.4 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAX99753.1 - 8.2e-05 22.8 0.1 0.19 12.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF4476 PF14771.6 EAX99753.1 - 0.0036 17.6 5.0 0.73 10.2 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) DUF4385 PF14328.6 EAX99753.1 - 0.05 13.7 1.2 1.4 8.9 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4385) DUF4300 PF14133.6 EAX99753.1 - 0.17 11.6 7.1 0.25 11.0 0.2 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4300) Ank_2 PF12796.7 EAX99755.1 - 3.3e-06 27.6 0.0 0.032 14.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX99755.1 - 5.9e-05 23.0 0.6 0.0099 15.8 0.1 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX99755.1 - 0.00097 19.7 0.0 0.36 11.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) WD40 PF00400.32 EAX99757.1 - 1.7e-47 158.4 12.3 1.2e-05 25.9 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX99757.1 - 8.3e-17 61.3 1.1 3.3e-05 24.1 0.0 6.2 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAX99757.1 - 1.2e-06 27.5 8.4 0.41 9.2 0.0 5.4 2 1 3 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EAX99757.1 - 6.3e-05 22.4 1.0 0.0037 16.6 0.1 3.5 1 1 3 4 4 4 1 WD40-like domain eIF2A PF08662.11 EAX99757.1 - 0.0003 20.7 2.0 0.0057 16.5 0.0 3.3 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAX99757.1 - 0.023 13.7 1.9 0.23 10.4 0.1 3.2 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IGFL PF14653.6 EAX99757.1 - 0.14 12.2 0.8 0.29 11.1 0.8 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family DUF1447 PF07288.11 EAX99758.1 - 0.0073 16.3 1.1 0.039 14.0 1.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1447) ACP_PD PF04336.12 EAX99758.1 - 0.24 11.9 10.4 4.8 7.6 0.3 5.5 5 1 1 6 6 6 0 Acyl carrier protein phosphodiesterase DUF4023 PF13215.6 EAX99758.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4023) MCPVI PF02993.14 EAX99758.1 - 1.2 8.9 3.3 2.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Minor capsid protein VI Filament PF00038.21 EAX99758.1 - 2.1 7.9 44.0 0.38 10.3 11.6 4.5 4 1 0 4 4 4 0 Intermediate filament protein HSBP1 PF06825.12 EAX99758.1 - 2.7 7.9 19.7 6.8 6.6 0.2 6.1 6 0 0 6 6 6 0 Heat shock factor binding protein 1 Fez1 PF06818.15 EAX99758.1 - 4.6 7.7 41.4 0.055 13.9 9.1 3.8 3 1 1 4 4 4 0 Fez1 DUF3006 PF11213.8 EAX99759.1 - 0.081 13.2 0.2 16 5.8 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3006) LRR_5 PF13306.6 EAX99760.1 - 2e-286 933.0 284.9 1.3e-33 115.7 8.6 16.7 7 3 12 19 19 19 17 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99760.1 - 1.3e-17 63.2 53.8 0.0043 16.8 0.0 18.8 22 0 0 22 22 22 11 Leucine rich repeat DUF4156 PF13698.6 EAX99760.1 - 0.16 12.3 0.0 99 3.4 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF4156) TTL PF03133.15 EAX99761.1 - 3.6e-53 180.6 0.1 4.7e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX99761.1 - 6.1e-11 42.1 0.1 0.00016 21.0 0.0 3.2 1 1 2 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX99761.1 - 2.4e-07 30.3 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX99761.1 - 0.0004 20.5 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EAX99761.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Endotoxin_N PF03945.14 EAX99762.1 - 0.0039 16.9 2.8 0.0039 16.9 2.8 1.5 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain Cse1 PF08506.10 EAX99762.1 - 0.0062 15.4 2.9 0.012 14.5 2.8 1.4 1 1 0 1 1 1 1 Cse1 FliG_C PF01706.16 EAX99762.1 - 0.05 13.8 0.7 0.065 13.4 0.7 1.1 1 0 0 1 1 1 0 FliG C-terminal domain adh_short PF00106.25 EAX99762.1 - 0.052 13.0 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase DUF412 PF04217.13 EAX99762.1 - 0.13 12.1 0.4 0.17 11.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF412 EF-hand_1 PF00036.32 EAX99763.1 - 1.1e-23 80.9 15.0 7.7e-09 34.5 0.7 4.4 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAX99763.1 - 3.1e-22 78.8 9.4 1.9e-12 47.5 3.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAX99763.1 - 8.2e-19 65.9 16.6 2.8e-07 29.9 1.0 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EAX99763.1 - 1.3e-13 49.7 12.7 4.5e-05 22.7 0.4 5.1 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 EAX99763.1 - 2e-11 43.5 10.8 3.4e-06 26.8 1.3 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EAX99763.1 - 0.00029 20.7 8.7 0.75 9.8 0.1 3.2 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EAX99763.1 - 0.00079 19.2 8.5 0.018 14.9 1.4 3.1 2 1 2 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EAX99763.1 - 0.0055 17.0 6.5 0.088 13.1 1.5 3.0 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region IF2_N PF04760.15 EAX99763.1 - 0.0078 16.0 7.6 0.99 9.3 0.1 3.8 3 2 1 4 4 4 1 Translation initiation factor IF-2, N-terminal region RST PF12174.8 EAX99763.1 - 0.0098 15.8 0.3 0.025 14.5 0.3 1.6 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain DUF1456 PF07308.13 EAX99763.1 - 0.041 14.2 1.4 1.8 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Pam16 PF03656.13 EAX99763.1 - 0.074 13.1 1.7 4.6 7.3 0.2 2.1 2 0 0 2 2 2 0 Pam16 p25-alpha PF05517.12 EAX99763.1 - 0.075 13.2 1.5 0.8 9.9 1.4 2.0 2 0 0 2 2 2 0 p25-alpha EF-hand_9 PF14658.6 EAX99763.1 - 0.13 12.6 1.0 9.7 6.6 0.0 2.8 3 1 0 3 3 3 0 EF-hand domain PRESAN PF09687.10 EAX99763.1 - 0.18 12.3 6.1 0.15 12.6 2.4 2.5 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Ank_2 PF12796.7 EAX99764.1 - 5.2e-08 33.4 0.1 0.00014 22.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99764.1 - 1.2e-05 25.3 0.4 0.07 13.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX99764.1 - 7.3e-05 23.2 0.2 0.73 10.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99764.1 - 0.01 15.8 6.5 0.038 13.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Ank PF00023.30 EAX99764.1 - 0.013 16.0 0.0 5.2 7.7 0.0 2.9 4 0 0 4 4 4 0 Ankyrin repeat VHL_C PF17211.3 EAX99764.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 VHL box domain zf-C2H2_2 PF12756.7 EAX99765.1 - 3e-05 24.3 15.5 0.022 15.1 1.6 3.7 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EAX99765.1 - 0.021 15.3 18.7 0.07 13.6 0.9 3.7 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D CxC3 PF18804.1 EAX99765.1 - 0.07 13.0 2.3 9.9 6.1 0.0 3.4 2 1 1 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases PyrI_C PF02748.15 EAX99765.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 EAX99765.1 - 2.2 8.9 27.9 0.84 10.2 1.6 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EAX99765.1 - 2.2 8.9 11.9 12 6.6 0.3 3.7 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EAX99765.1 - 3 8.9 27.3 1.4 9.9 0.3 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger DUF3447 PF11929.8 EAX99766.1 - 0.0014 18.6 14.6 0.0085 16.0 0.2 4.5 4 1 0 4 4 4 2 Domain of unknown function (DUF3447) IL34 PF15036.6 EAX99766.1 - 0.0046 17.0 0.4 0.5 10.4 0.1 3.8 2 1 1 3 3 3 1 Interleukin 34 Ank_3 PF13606.6 EAX99766.1 - 0.0054 17.1 0.0 11 7.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 EAX99766.1 - 0.014 15.9 0.2 14 6.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Vps23_core PF09454.10 EAX99766.1 - 0.043 13.8 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Vps23 core domain PAP2 PF01569.21 EAX99767.1 - 5.3e-24 84.5 2.6 1e-23 83.6 2.6 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EAX99767.1 - 4.7e-05 23.2 4.0 9.5e-05 22.2 4.0 1.5 1 1 0 1 1 1 1 PAP2 superfamily DAGK_cat PF00781.24 EAX99767.1 - 0.045 13.4 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF1449 PF07290.11 EAX99767.1 - 0.052 13.2 0.7 0.084 12.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) PAP2_C PF14360.6 EAX99767.1 - 2 9.0 10.7 0.11 13.1 2.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal FANCI_S2 PF14676.6 EAX99768.1 - 1.3 9.3 13.1 0.88 9.9 3.0 4.5 3 1 1 4 4 4 0 FANCI solenoid 2 ABC_tran PF00005.27 EAX99769.1 - 2.1e-29 102.8 0.0 4.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX99769.1 - 1.2e-08 35.1 1.6 0.0053 16.6 1.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAX99769.1 - 2.5e-05 23.9 0.1 5.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX99769.1 - 2.9e-05 23.6 0.4 0.037 13.5 0.3 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAX99769.1 - 0.00011 22.2 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EAX99769.1 - 0.00081 19.9 0.4 0.00081 19.9 0.4 2.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EAX99769.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CENP-P PF13096.6 EAX99769.1 - 0.0098 15.6 1.6 3.2 7.4 0.0 2.6 2 0 0 2 2 2 2 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P IstB_IS21 PF01695.17 EAX99769.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_15 PF13175.6 EAX99769.1 - 0.013 15.3 0.4 0.013 15.3 0.4 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.6 EAX99769.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAX99769.1 - 0.026 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EAX99769.1 - 0.027 13.6 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EAX99769.1 - 0.027 14.5 0.5 0.078 13.1 0.5 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAX99769.1 - 0.035 14.4 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAX99769.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAX99770.1 - 4.2e-13 50.0 0.0 7.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX99770.1 - 3.5e-12 46.1 23.8 6.5e-12 45.2 23.8 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein cobW PF02492.19 EAX99770.1 - 0.063 12.9 0.7 0.76 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EAX99770.1 - 0.073 13.6 1.5 0.16 12.5 1.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAX99770.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF4107 PF13389.6 EAX99772.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Pkinase PF00069.25 EAX99773.1 - 2.9e-53 180.9 0.6 3.7e-53 180.6 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99773.1 - 5.5e-34 117.6 0.0 6.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99773.1 - 4.5e-08 32.8 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAX99773.1 - 0.0016 17.6 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Trns_repr_metal PF02583.17 EAX99773.1 - 0.011 16.1 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Pkinase PF00069.25 EAX99774.1 - 1.2e-56 192.1 0.2 1.6e-56 191.6 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99774.1 - 7.2e-36 123.8 0.0 9.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99774.1 - 4.6e-09 36.0 0.0 5.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX99774.1 - 8.3e-05 22.0 0.6 0.00017 21.0 0.6 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAX99774.1 - 0.00059 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAX99774.1 - 0.023 13.8 0.2 0.041 12.9 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EAX99774.1 - 0.03 14.3 0.0 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EAX99775.1 - 2.8e-51 174.4 0.4 3.2e-51 174.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99775.1 - 2e-23 83.0 0.0 2.3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAX99775.1 - 0.00014 21.3 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAX99775.1 - 0.00047 19.6 0.0 0.00089 18.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAX99775.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EAX99776.1 - 1.6e-55 188.3 0.1 2.2e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99776.1 - 1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99776.1 - 6.6e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAX99776.1 - 0.0027 16.6 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAX99776.1 - 0.009 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAX99776.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAX99777.1 - 9.3e-36 123.5 0.1 1.3e-35 123.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99777.1 - 6e-22 78.2 0.0 9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99777.1 - 8.1e-05 22.1 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAX99777.1 - 0.2 11.0 0.2 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_TH1 PF06017.13 EAX99778.1 - 4.3e-28 98.3 0.3 5.8e-28 97.8 0.3 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding DUF4065 PF13274.6 EAX99778.1 - 0.13 13.2 0.7 0.41 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF2939 PF11159.8 EAX99779.1 - 0.016 15.6 0.4 0.023 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAX99779.1 - 2.7 8.0 5.1 2.9 7.9 5.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAX99780.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAX99780.1 - 0.12 12.4 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAX99781.1 - 8.2e-23 81.0 8.6 8.9e-22 77.6 7.8 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF5106 PF17127.4 EAX99781.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) gpUL132 PF11359.8 EAX99781.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Amidase02_C PF12123.8 EAX99783.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX99784.1 - 4.7e-66 221.9 12.9 2.2e-64 216.5 12.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) LRR_5 PF13306.6 EAX99786.1 - 3.3e-55 185.5 37.8 6.1e-23 81.2 7.6 4.7 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99786.1 - 4.1e-12 45.7 2.1 0.00033 20.4 0.0 5.7 3 2 4 7 7 7 4 Leucine rich repeat LRR_5 PF13306.6 EAX99787.1 - 0.0011 18.9 4.3 0.84 9.6 1.3 2.8 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) S_4TM PF18159.1 EAX99787.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain LRR_5 PF13306.6 EAX99789.1 - 4.2e-38 130.2 32.8 4e-19 68.8 14.4 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99789.1 - 4.6e-09 35.9 0.4 0.00079 19.1 0.1 3.9 3 2 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 EAX99790.1 - 2.1e-21 76.2 21.2 8.6e-17 61.3 3.7 2.9 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EAX99790.1 - 0.0008 19.8 0.3 5.2 7.6 0.0 4.3 2 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAX99790.1 - 0.003 17.3 0.0 1.1 9.1 0.0 4.1 2 2 3 5 5 5 2 Leucine rich repeat Phage_int_SAM_5 PF13102.6 EAX99790.1 - 0.009 16.3 0.1 0.025 14.9 0.0 1.7 2 0 0 2 2 2 1 Phage integrase SAM-like domain LRR_5 PF13306.6 EAX99792.1 - 1.9e-08 34.3 0.9 3.8e-08 33.3 0.9 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Orf78 PF06024.12 EAX99792.1 - 0.0035 17.6 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) DUF3481 PF11980.8 EAX99792.1 - 0.0086 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein Ank_2 PF12796.7 EAX99793.1 - 2.6e-83 274.7 25.9 9e-16 58.2 0.2 9.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99793.1 - 6.4e-63 206.6 18.6 9.1e-06 25.9 0.1 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 EAX99793.1 - 1.1e-59 191.4 28.2 1.1e-05 25.4 0.1 15.3 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 EAX99793.1 - 1.2e-59 197.6 19.9 2.5e-11 43.6 0.2 11.0 5 1 6 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99793.1 - 2.1e-59 197.2 29.4 1.2e-13 51.2 0.1 14.3 4 2 11 15 15 15 12 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAX99793.1 - 1.3e-15 57.1 6.9 1.3e-15 57.1 6.9 5.8 5 3 2 7 7 7 1 Domain of unknown function (DUF3447) Ribosomal_S4e PF00900.20 EAX99793.1 - 0.0063 16.4 0.1 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal family S4e Myb_DNA-binding PF00249.31 EAX99795.1 - 0.00029 21.0 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99795.1 - 0.014 15.7 0.1 0.12 12.6 0.0 2.3 1 1 1 2 2 2 0 Myb-like DNA-binding domain SLIDE PF09111.10 EAX99795.1 - 0.014 15.4 0.3 0.024 14.7 0.2 1.4 1 1 0 1 1 1 0 SLIDE PNPase PF03726.14 EAX99795.1 - 0.06 13.8 0.2 0.13 12.8 0.2 1.5 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RRM_1 PF00076.22 EAX99796.1 - 1.7e-05 24.5 0.1 4.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EAX99796.1 - 0.045 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Ank_2 PF12796.7 EAX99797.1 - 6.7e-41 138.8 9.3 9.7e-12 45.3 0.2 6.5 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99797.1 - 3.9e-35 119.8 5.5 2.5e-08 34.3 0.0 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99797.1 - 1.5e-30 104.8 3.8 1.9e-06 28.0 0.0 8.6 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99797.1 - 2.7e-28 94.9 5.3 0.0013 19.1 0.0 10.9 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 EAX99797.1 - 2e-21 75.4 1.8 0.025 15.0 0.0 8.8 10 0 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAX99797.1 - 2.7e-16 59.3 4.2 2.7e-16 59.3 4.2 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) ECSIT PF06239.11 EAX99797.1 - 0.035 13.2 0.3 0.056 12.6 0.3 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Glyco_hydro_14 PF01373.17 EAX99798.1 - 3.4e-94 316.1 10.3 3.9e-94 315.9 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Fringe PF02434.16 EAX99799.1 - 2.6e-06 27.0 0.0 5.3e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EAX99799.1 - 0.098 12.5 0.0 0.49 10.2 0.0 2.2 1 1 0 1 1 1 0 Galactosyltransferase Lsm_interact PF05391.11 EAX99800.1 - 2.9 7.5 6.1 16 5.2 1.0 3.2 2 0 0 2 2 2 0 Lsm interaction motif DUF4407 PF14362.6 EAX99800.1 - 7.8 5.7 35.6 0.5 9.7 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.21 EAX99801.1 - 3.2e-44 151.3 0.0 5.2e-44 150.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 EAX99801.1 - 0.12 12.4 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 S-layer homology domain F5_F8_type_C PF00754.25 EAX99803.1 - 1.2e-06 28.7 0.2 3e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 F5/8 type C domain GCN5L1 PF06320.13 EAX99805.1 - 0.097 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) IPK PF03770.16 EAX99806.1 - 2.3e-37 128.8 0.1 3.4e-37 128.2 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Omp_AT PF11557.8 EAX99807.1 - 0.026 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain DUF3839 PF12943.7 EAX99808.1 - 1.1e-152 506.3 13.7 1.5e-152 505.9 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAX99808.1 - 0.045 14.2 1.5 1.8 9.1 0.1 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAX99808.1 - 0.14 12.4 3.5 15 6.0 0.0 3.7 4 0 0 4 4 4 0 Tup N-terminal Amidase02_C PF12123.8 EAX99810.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAX99811.1 - 4.8e-71 238.2 3.3 7.3e-71 237.6 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAX99811.1 - 0.061 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta FLYWCH PF04500.16 EAX99813.1 - 0.081 13.0 4.7 0.15 12.2 4.7 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain dCMP_cyt_deam_1 PF00383.23 EAX99814.1 - 7.1e-26 90.0 1.3 8.8e-26 89.7 1.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAX99814.1 - 1e-23 83.6 0.2 1.2e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EAX99814.1 - 0.00014 22.0 0.1 0.0002 21.4 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 EAX99814.1 - 0.0006 19.9 0.1 0.00088 19.4 0.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 EAX99814.1 - 0.00063 19.8 4.8 0.02 14.9 4.8 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.11 EAX99814.1 - 0.0011 18.9 0.1 0.0013 18.6 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 EAX99814.1 - 0.0013 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 EAX99814.1 - 0.0065 16.6 0.1 0.0096 16.0 0.1 1.2 1 0 0 1 1 1 1 APOBEC3 NAD2 PF18782.1 EAX99814.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 XOO_2897-deam PF14440.6 EAX99814.1 - 0.058 13.5 0.1 0.094 12.8 0.1 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase SNAD1 PF18744.1 EAX99814.1 - 0.064 13.1 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 APOBEC1 PF18769.1 EAX99814.1 - 0.066 13.5 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 APOBEC4_like PF18774.1 EAX99814.1 - 0.076 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Pkinase PF00069.25 EAX99816.1 - 9.6e-41 139.9 0.0 1.2e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99816.1 - 1.5e-25 90.0 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SET PF00856.28 EAX99817.1 - 9.6e-12 45.6 8.8 5.5e-11 43.1 0.1 3.5 2 2 0 2 2 2 1 SET domain Asp-B-Hydro_N PF05279.11 EAX99817.1 - 3.4 7.7 19.6 5.4 7.0 19.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mem_trans PF03547.18 EAX99818.1 - 1e-16 60.4 22.7 3.5e-16 58.6 7.2 2.0 1 1 1 2 2 2 2 Membrane transport protein TMEM171 PF15471.6 EAX99818.1 - 1.2 8.1 4.1 2.4 7.1 4.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 FYVE PF01363.21 EAX99819.1 - 3e-20 72.1 7.6 6.4e-20 71.1 7.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EAX99819.1 - 0.00013 22.2 5.4 0.00032 20.9 5.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PH PF00169.29 EAX99819.1 - 0.0027 18.2 0.0 0.0069 16.9 0.0 1.7 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 EAX99819.1 - 0.032 14.2 0.2 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 PH domain DUF1548 PF07579.11 EAX99819.1 - 0.063 13.6 1.8 0.67 10.3 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DZR PF12773.7 EAX99819.1 - 3.3 7.8 8.6 26 5.0 8.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon SR-25 PF10500.9 EAX99820.1 - 0.0085 15.7 28.0 0.0085 15.7 28.0 3.6 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.26 EAX99820.1 - 0.11 13.0 3.0 0.3 11.6 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type OTT_1508_deam PF14441.6 EAX99820.1 - 0.25 11.4 1.8 0.83 9.7 1.8 1.9 1 0 0 1 1 1 0 OTT_1508-like deaminase PSCyt3 PF07627.11 EAX99820.1 - 0.69 10.2 7.8 0.074 13.3 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) zf-C2H2_2 PF12756.7 EAX99820.1 - 1.3 9.4 11.3 0.083 13.2 5.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TRAP-gamma PF07074.12 EAX99820.1 - 2.2 7.8 7.0 0.29 10.7 1.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) zf-C2H2_jaz PF12171.8 EAX99820.1 - 3.9 7.9 9.3 0.21 11.9 2.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Peptidase_M48 PF01435.18 EAX99821.1 - 8.6e-11 42.0 0.0 1.2e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M48 GntP_permease PF02447.16 EAX99821.1 - 0.032 12.9 0.1 0.056 12.1 0.1 1.4 1 0 0 1 1 1 0 GntP family permease Ank_2 PF12796.7 EAX99822.1 - 1.5e-09 38.3 0.1 1.1e-07 32.3 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99822.1 - 1.5e-05 25.4 0.9 0.00055 20.4 0.0 3.5 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99822.1 - 0.00037 20.7 0.3 0.73 10.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99822.1 - 0.0014 18.9 0.0 6.7 7.6 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat BTHB PF18410.1 EAX99822.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Basic tilted helix bundle domain Cpn60_TCP1 PF00118.24 EAX99823.1 - 1.3e-93 314.3 16.0 2.3e-93 313.5 16.0 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Big_8 PF17961.1 EAX99824.1 - 0.024 14.7 0.3 0.06 13.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig domain B3R PF17057.5 EAX99824.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxviridae B3 protein SH3_5 PF08460.10 EAX99824.1 - 0.059 13.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain WD40_like PF17005.5 EAX99825.1 - 4.6e-06 26.2 14.2 0.00014 21.3 7.2 2.7 2 1 1 3 3 3 2 WD40-like domain DUF945 PF06097.11 EAX99825.1 - 0.0054 15.9 0.0 0.008 15.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) BBS2_Mid PF14783.6 EAX99825.1 - 0.084 12.9 1.2 12 6.0 0.0 3.4 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 EAX99825.1 - 0.088 12.7 0.1 8.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF4075 PF13294.6 EAX99825.1 - 0.23 11.6 5.2 26 5.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4075) Rpr2 PF04032.16 EAX99826.1 - 8.6e-11 42.0 0.2 8.6e-11 42.0 0.2 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_10 PF10058.9 EAX99826.1 - 0.93 9.3 5.0 14 5.5 5.0 2.2 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Pkinase PF00069.25 EAX99827.1 - 8.7e-26 90.8 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99827.1 - 5.3e-12 45.6 0.0 6.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAX99827.1 - 0.00044 20.3 0.0 0.0016 18.4 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAX99827.1 - 0.00053 18.9 0.1 0.00081 18.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAX99827.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family STE PF02200.16 EAX99827.1 - 0.077 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 STE like transcription factor ASFV_J13L PF05568.11 EAX99828.1 - 0.091 12.5 1.9 0.15 11.8 1.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Phage_holin_6_1 PF09682.10 EAX99828.1 - 0.17 12.3 6.3 0.15 12.5 1.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ank_2 PF12796.7 EAX99829.1 - 1.5e-11 44.7 1.5 6.8e-10 39.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99829.1 - 9.9e-10 38.8 0.1 6.3e-05 23.4 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99829.1 - 0.0005 20.3 0.1 1.6 9.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-MIZ PF02891.20 EAX99830.1 - 5.8e-15 54.8 3.3 1.5e-14 53.4 3.3 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Vps36-NZF-N PF16988.5 EAX99830.1 - 0.001 18.4 0.8 0.0029 17.0 0.8 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EAX99830.1 - 0.012 15.6 0.4 0.058 13.4 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.6 EAX99830.1 - 0.12 12.7 1.9 0.34 11.3 1.9 1.8 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 EAX99830.1 - 0.74 9.8 6.1 0.12 12.3 2.0 1.8 2 0 0 2 2 2 0 PHD-finger DUF2407_C PF13373.6 EAX99831.1 - 0.46 10.6 12.6 0.05 13.8 3.4 2.4 2 1 0 2 2 2 0 DUF2407 C-terminal domain ABC2_membrane_3 PF12698.7 EAX99831.1 - 3.1 6.8 4.8 3.9 6.5 4.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CHDCT2 PF08074.11 EAX99831.1 - 7 6.8 14.0 0.57 10.3 5.5 2.4 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF5320 PF17253.2 EAX99831.1 - 7.6 7.7 5.2 26 5.9 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) CCD48 PF15799.5 EAX99832.1 - 0.27 9.5 6.2 0.13 10.5 4.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 HypF_C PF17788.1 EAX99832.1 - 0.45 11.2 4.3 5.7 7.7 0.1 2.9 1 1 0 3 3 3 0 HypF Kae1-like domain Nup54 PF13874.6 EAX99832.1 - 0.53 10.4 20.9 0.028 14.5 9.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 T3SSipB PF16535.5 EAX99832.1 - 0.87 10.0 21.7 1.7 9.1 6.9 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB MAD PF05557.13 EAX99832.1 - 1.1 7.5 34.2 1.3 7.3 34.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein vWA-TerF-like PF10138.9 EAX99832.1 - 1.6 8.8 6.5 0.98 9.5 0.3 2.5 1 1 1 2 2 2 0 vWA found in TerF C terminus Syntaxin-6_N PF09177.11 EAX99832.1 - 2 9.0 18.5 4.7 7.8 5.7 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EAX99832.1 - 2.3 7.0 36.3 1.7 7.5 14.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Endonuc-dimeris PF09124.10 EAX99832.1 - 2.6 8.3 9.8 0.16 12.2 1.3 3.2 2 1 1 3 3 3 0 T4 recombination endonuclease VII, dimerisation DUF3452 PF11934.8 EAX99832.1 - 3.5 7.2 10.8 0.11 12.0 2.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3452) DUF948 PF06103.11 EAX99832.1 - 7.3 6.9 13.7 2.6 8.3 2.8 3.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PilO PF04350.13 EAX99832.1 - 8.1 6.6 23.4 0.74 10.0 2.5 2.8 1 1 2 3 3 3 0 Pilus assembly protein, PilO ATG16 PF08614.11 EAX99833.1 - 9.5e-07 29.2 156.3 0.013 15.7 34.8 8.3 1 1 4 6 6 6 4 Autophagy protein 16 (ATG16) ADIP PF11559.8 EAX99833.1 - 9.5e-07 29.0 180.7 0.0012 19.0 22.9 10.0 2 2 8 10 10 10 6 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EAX99833.1 - 2.4e-06 26.7 174.2 0.0026 16.7 20.2 6.4 1 1 5 6 6 6 4 Spc7 kinetochore protein APG6_N PF17675.1 EAX99833.1 - 0.00016 22.2 167.5 0.03 14.8 14.0 9.7 1 1 8 10 10 10 5 Apg6 coiled-coil region ZapB PF06005.12 EAX99833.1 - 0.00098 19.5 196.2 0.24 11.9 9.1 15.2 3 3 10 13 13 13 3 Cell division protein ZapB KASH_CCD PF14662.6 EAX99833.1 - 0.0074 16.1 33.2 0.0074 16.1 33.2 9.1 1 1 7 9 9 9 3 Coiled-coil region of CCDC155 or KASH DHR10 PF18595.1 EAX99833.1 - 0.01 15.9 4.2 0.01 15.9 4.2 10.3 2 2 7 10 10 9 0 Designed helical repeat protein 10 domain TMF_TATA_bd PF12325.8 EAX99833.1 - 0.013 15.7 149.8 0.25 11.6 17.9 11.4 2 2 10 12 12 12 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EAX99833.1 - 0.37 10.8 177.5 0.057 13.4 25.0 8.6 1 1 7 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EAX99833.1 - 0.75 8.6 137.9 0.086 11.7 37.7 5.1 1 1 3 5 5 5 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 EAX99833.1 - 1.1 9.4 172.7 0.24 11.5 19.3 9.7 2 1 9 11 11 10 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 EAX99833.1 - 1.6 7.2 10.3 5.5 5.4 0.4 3.6 1 1 3 4 4 4 0 Fusaric acid resistance protein family Fez1 PF06818.15 EAX99833.1 - 1.6 9.1 143.8 0.8 10.1 23.7 7.0 1 1 5 6 6 6 0 Fez1 DUF3450 PF11932.8 EAX99833.1 - 1.9 7.8 148.4 0.14 11.4 12.6 9.6 1 1 6 9 9 9 0 Protein of unknown function (DUF3450) ERM PF00769.19 EAX99833.1 - 3.6 7.3 145.8 0.12 12.2 28.8 5.8 1 1 4 5 5 5 0 Ezrin/radixin/moesin family Filament PF00038.21 EAX99833.1 - 7.5 6.0 148.0 8.3 5.9 32.8 5.8 1 1 2 3 3 3 0 Intermediate filament protein FAM184 PF15665.5 EAX99834.1 - 1 9.1 148.7 0.21 11.3 23.8 8.4 1 1 7 8 8 8 0 Family with sequence similarity 184, A and B DUF4106 PF13388.6 EAX99835.1 - 5 6.3 11.6 5.1 6.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PTR PF12789.7 EAX99836.1 - 1.2e-16 60.5 1.3 1.2e-16 60.5 1.3 3.4 5 0 0 5 5 5 1 Phage tail repeat like Gly-zipper_Omp PF13488.6 EAX99838.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAX99838.1 - 0.3 11.4 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAX99838.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif EpuA PF11772.8 EAX99840.1 - 0.17 11.6 0.0 0.63 9.8 0.0 2.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Thioredoxin PF00085.20 EAX99841.1 - 7.2e-22 77.3 0.1 8.3e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAX99841.1 - 2.1e-05 24.9 0.0 6.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAX99841.1 - 8.5e-05 22.0 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EAX99841.1 - 0.00014 22.0 0.0 0.00049 20.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EAX99841.1 - 0.00051 20.3 0.0 0.0016 18.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EAX99841.1 - 0.0017 18.6 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EAX99841.1 - 0.0041 17.1 0.0 0.0057 16.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EAX99841.1 - 0.0057 17.0 0.0 0.0077 16.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 EAX99841.1 - 0.011 15.4 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Redoxin CM2 PF03021.14 EAX99841.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Influenza C virus M2 protein AhpC-TSA PF00578.21 EAX99841.1 - 0.037 14.0 0.1 0.069 13.1 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EAX99841.1 - 0.041 13.7 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_6 PF13848.6 EAX99841.1 - 0.074 13.0 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_S8 PF00082.22 EAX99842.1 - 6.3e-35 120.9 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family FAM176 PF14851.6 EAX99842.1 - 0.029 14.0 0.7 0.046 13.4 0.7 1.3 1 0 0 1 1 1 0 FAM176 family BRCA-2_OB3 PF09104.10 EAX99844.1 - 0.23 11.1 4.9 0.13 12.0 1.2 2.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF1664 PF07889.12 EAX99844.1 - 0.4 10.7 33.8 0.012 15.7 10.0 5.5 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Cytochrom_C_2 PF01322.20 EAX99844.1 - 0.54 11.2 9.7 1.2 10.1 0.0 4.4 3 1 1 4 4 4 0 Cytochrome C' ATG16 PF08614.11 EAX99844.1 - 1 9.6 33.3 0.61 10.3 13.5 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PIN_2 PF10130.9 EAX99844.1 - 1.2 9.4 12.8 12 6.1 1.5 4.7 3 2 1 4 4 4 0 PIN domain DUF3584 PF12128.8 EAX99844.1 - 1.5 6.3 33.7 0.19 9.2 28.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran_CTD PF16326.5 EAX99844.1 - 1.5 9.1 21.9 5.2 7.4 0.9 4.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF5093 PF17011.5 EAX99844.1 - 3.7 7.8 15.5 0.7 10.2 1.2 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5093) DUF4763 PF15960.5 EAX99844.1 - 6.4 6.0 31.6 1.1 8.5 18.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Val_tRNA-synt_C PF10458.9 EAX99844.1 - 7.3 7.0 12.7 14 6.0 1.2 4.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FliJ PF02050.16 EAX99844.1 - 7.4 6.8 32.2 6.8 6.9 2.8 3.9 2 1 2 4 4 4 0 Flagellar FliJ protein TB2_DP1_HVA22 PF03134.19 EAX99846.1 - 0.0005 20.0 3.3 0.0065 16.4 0.4 2.3 2 0 0 2 2 2 2 TB2/DP1, HVA22 family Ribosomal_S13 PF00416.22 EAX99847.1 - 1.2e-35 122.6 0.4 1.4e-35 122.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 EAX99847.1 - 0.0097 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain DUF3839 PF12943.7 EAX99849.1 - 2.4e-137 456.1 10.4 3e-137 455.8 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAX99849.1 - 0.027 14.9 0.9 0.027 14.9 0.9 2.0 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAX99849.1 - 0.077 13.4 0.4 0.88 10.0 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2408 PF10303.9 EAX99849.1 - 0.24 11.9 3.7 0.24 12.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAX99849.1 - 1.5 9.3 9.1 3.6 8.1 0.5 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAX99850.1 - 3.1e-32 110.7 0.4 7.6e-32 109.5 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAX99850.1 - 0.0028 17.8 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Cep57_MT_bd PF06657.13 EAX99850.1 - 0.073 13.5 5.2 0.68 10.4 1.3 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pox_A32 PF04665.12 EAX99851.1 - 5.5e-08 32.6 1.1 6.7e-08 32.3 1.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX99851.1 - 0.0034 17.0 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAX99851.1 - 0.055 13.0 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAX99851.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAX99851.1 - 0.071 13.1 0.4 0.62 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Pox_A32 PF04665.12 EAX99853.1 - 7.8e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX99853.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAX99853.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAX99853.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 WD40 PF00400.32 EAX99854.1 - 1.7e-05 25.4 1.2 0.0091 16.8 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAX99854.1 - 0.033 14.5 0.0 16 5.9 0.0 3.6 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain T3SSipB PF16535.5 EAX99854.1 - 0.036 14.5 0.1 0.064 13.7 0.1 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB APG6_N PF17675.1 EAX99854.1 - 0.04 14.4 0.4 0.07 13.7 0.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 EAX99854.1 - 0.069 13.5 0.8 0.098 12.9 0.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein NPA PF16469.5 EAX99854.1 - 0.12 13.0 0.2 0.21 12.2 0.2 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Cep57_MT_bd PF06657.13 EAX99854.1 - 0.79 10.2 3.3 36 4.9 3.4 2.4 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ras PF00071.22 EAX99855.1 - 1.8e-49 167.4 0.3 2e-49 167.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99855.1 - 2.8e-33 114.7 0.3 3.9e-33 114.2 0.1 1.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99855.1 - 1.3e-14 54.1 0.0 1.4e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX99855.1 - 5.7e-06 26.4 0.0 7.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99855.1 - 0.00018 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EAX99855.1 - 0.0003 20.5 0.2 0.00086 19.1 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EAX99855.1 - 0.012 15.8 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAX99855.1 - 0.016 15.2 0.1 13 5.7 0.0 2.9 2 1 1 3 3 3 0 RsgA GTPase HypF_C PF17788.1 EAX99855.1 - 0.016 15.9 0.1 0.024 15.3 0.1 1.2 1 0 0 1 1 1 0 HypF Kae1-like domain GTP_EFTU PF00009.27 EAX99855.1 - 0.018 14.6 0.1 1.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX99855.1 - 0.05 13.0 0.0 0.062 12.7 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EAX99855.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EAX99855.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ank_2 PF12796.7 EAX99856.1 - 5.7e-149 485.1 51.5 3.4e-17 62.8 0.7 15.0 1 1 15 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99856.1 - 1.3e-114 373.2 39.1 9.1e-12 45.3 0.1 23.2 6 5 18 25 25 25 23 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99856.1 - 2.3e-113 368.7 34.6 1.5e-10 41.1 0.2 22.0 3 3 22 26 26 26 26 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99856.1 - 1e-112 354.3 34.8 0.00055 20.2 0.2 29.7 30 0 0 30 30 30 26 Ankyrin repeat Ank PF00023.30 EAX99856.1 - 1.4e-91 297.3 31.2 0.001 19.4 0.5 27.8 27 1 1 28 28 28 21 Ankyrin repeat CdAMP_rec PF06153.11 EAX99856.1 - 0.24 11.6 3.7 49 4.2 0.0 5.1 5 1 0 5 5 5 0 Cyclic-di-AMP receptor Glyco_hydro_15 PF00723.21 EAX99859.1 - 1.6e-07 30.5 0.1 1.3e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 F5_F8_type_C PF00754.25 EAX99860.1 - 2.1e-06 27.9 0.1 0.00029 21.0 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain F5_F8_type_C PF00754.25 EAX99861.1 - 2.7e-07 30.7 0.2 2.5e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 F5/8 type C domain Helicase_C PF00271.31 EAX99862.1 - 2.8e-06 27.7 0.5 2.6e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAX99862.1 - 4.1e-06 26.7 0.5 4.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 EAX99862.1 - 0.096 13.0 0.0 0.096 13.0 0.0 4.5 2 1 0 2 2 2 0 Helicase associated domain (HA2) Syndecan PF01034.20 EAX99863.1 - 8.2e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAX99863.1 - 0.00014 22.1 0.1 0.00047 20.4 0.0 1.8 1 1 1 2 2 2 1 Glycophorin A DUF3377 PF11857.8 EAX99863.1 - 0.00056 19.8 0.2 0.0016 18.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Amnionless PF14828.6 EAX99863.1 - 0.00057 18.8 0.0 0.00066 18.6 0.0 1.1 1 0 0 1 1 1 1 Amnionless DUF4834 PF16118.5 EAX99863.1 - 0.015 16.2 0.4 0.039 14.9 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) TMEM171 PF15471.6 EAX99863.1 - 0.03 13.3 0.8 0.042 12.8 0.1 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 EphA2_TM PF14575.6 EAX99863.1 - 0.037 14.9 0.1 0.069 14.0 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 EAX99863.1 - 0.038 13.9 0.1 0.079 12.9 0.1 1.5 1 1 0 1 1 1 0 Myc target protein 1 ASFV_J13L PF05568.11 EAX99863.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM154 PF15102.6 EAX99863.1 - 0.089 12.7 5.5 0.38 10.7 4.8 2.3 1 1 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 EAX99863.1 - 0.1 12.9 3.7 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Orf78 (ac78) TMEM72 PF16054.5 EAX99863.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 72 Phage_holin_2_3 PF16080.5 EAX99863.1 - 0.17 11.7 0.3 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 NEMP PF10225.9 EAX99863.1 - 0.33 10.6 5.6 0.078 12.6 1.8 1.7 1 1 1 2 2 2 0 NEMP family Ly49 PF08391.10 EAX99863.1 - 0.4 11.1 3.8 0.85 10.0 3.8 1.8 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4106 PF13388.6 EAX99865.1 - 6.4e-267 885.4 18.9 6.4e-267 885.4 18.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Pox_A32 PF04665.12 EAX99866.1 - 4.3e-07 29.6 2.6 4.5e-07 29.6 1.9 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAX99866.1 - 0.0065 16.1 0.1 0.0091 15.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAX99866.1 - 0.097 12.4 0.1 0.31 10.7 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2666 PF10869.8 EAX99866.1 - 0.96 9.7 8.6 7.5 6.8 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF1493 PF07377.12 EAX99867.1 - 0.021 15.3 0.6 0.042 14.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99868.1 - 0.022 15.2 5.7 2.9 8.9 0.3 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99869.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_5 PF13306.6 EAX99870.1 - 4.2e-109 359.8 103.5 1.1e-27 96.5 16.7 6.7 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAX99870.1 - 8.2e-20 70.3 15.2 0.0077 16.0 0.3 8.8 5 1 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EAX99870.1 - 0.0034 17.8 20.7 0.59 10.6 1.3 7.4 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAX99870.1 - 0.39 10.9 9.1 1.6 8.9 0.6 4.9 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) DUF2897 PF11446.8 EAX99872.1 - 0.38 10.7 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAX99873.1 - 5.1e-61 204.8 6.0 5.7e-61 204.6 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX99873.1 - 0.11 12.7 0.4 4 7.7 0.1 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Gly_rich PF12810.7 EAX99874.1 - 4e-39 135.0 37.3 4.9e-39 134.7 37.3 1.1 1 0 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAX99876.1 - 6.9e-06 25.9 1.8 6.9e-06 25.9 1.8 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAX99876.1 - 0.0034 17.7 1.4 0.11 12.9 0.2 3.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99876.1 - 0.0071 16.9 1.5 0.023 15.3 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99876.1 - 0.098 13.3 0.7 82 4.3 0.1 4.2 2 1 1 3 3 3 0 Ankyrin repeat HNH_4 PF13395.6 EAX99876.1 - 0.12 12.3 1.5 0.32 10.9 0.3 2.3 1 1 1 2 2 2 0 HNH endonuclease DUF3839 PF12943.7 EAX99877.1 - 4.3e-159 527.3 13.3 5.5e-159 527.0 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAX99877.1 - 0.14 12.6 0.5 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAX99877.1 - 0.84 10.1 6.4 2.1 8.9 0.4 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAX99878.1 - 2.1e-23 82.2 13.0 2.1e-23 82.2 13.0 4.4 4 1 1 5 5 5 2 Phage tail repeat like Stathmin PF00836.19 EAX99878.1 - 3 7.8 6.7 0.78 9.7 2.0 2.3 2 0 0 2 2 2 0 Stathmin family DUF1493 PF07377.12 EAX99879.1 - 0.081 13.4 0.5 0.19 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99880.1 - 0.14 12.8 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAX99881.1 - 0.074 12.9 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAX99883.1 - 1.4e-42 144.1 22.8 1.2e-13 51.4 0.5 4.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAX99883.1 - 6.3e-39 131.8 7.8 6.3e-39 131.8 7.8 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX99883.1 - 8.8e-30 102.7 3.2 2.1e-11 44.1 0.0 7.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAX99883.1 - 3.4e-28 96.8 1.7 0.00011 22.5 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAX99883.1 - 2.7e-21 73.4 8.7 0.00013 22.2 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAX99883.1 - 2.1e-16 59.7 2.4 2.3e-07 31.0 0.1 5.1 4 1 2 6 6 6 2 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAX99883.1 - 0.031 14.4 3.9 2.9 8.1 0.2 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3718) DUF503 PF04456.12 EAX99883.1 - 0.034 14.0 0.0 13 5.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF503) SAB PF04382.13 EAX99883.1 - 1.7 8.7 3.7 98 3.1 0.1 3.9 4 0 0 4 4 4 0 SAB domain Ras PF00071.22 EAX99884.1 - 1.8e-51 174.0 0.0 2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99884.1 - 1.7e-31 108.9 0.0 8.4e-31 106.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99884.1 - 2.5e-14 53.1 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX99884.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99884.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX99884.1 - 0.00047 20.1 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAX99884.1 - 0.00086 18.9 0.1 0.12 12.0 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAX99884.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAX99884.1 - 0.099 12.2 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Tox-SGS PF15651.6 EAX99884.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.9 1 1 0 1 1 1 0 Salivary glad secreted protein domain toxin PMT PF02366.18 EAX99886.1 - 6.2e-36 124.2 10.8 6.2e-36 124.2 10.8 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAX99886.1 - 5.2e-14 52.3 15.2 5.2e-14 52.3 15.2 3.5 2 2 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase ATP-synt_I PF03899.15 EAX99886.1 - 0.82 10.1 9.1 1.1 9.7 2.1 2.9 2 1 0 2 2 2 0 ATP synthase I chain Imm6 PF14434.6 EAX99887.1 - 0.0049 16.8 1.4 0.016 15.1 1.4 1.9 1 0 0 1 1 1 1 Immunity protein Imm6 LCM PF04072.14 EAX99888.1 - 2.6e-17 63.4 0.0 1.2e-16 61.3 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Tetraspanin PF00335.20 EAX99890.1 - 0.00074 19.3 18.3 0.0013 18.5 18.3 1.4 1 1 0 1 1 1 1 Tetraspanin family TMEM70 PF06979.12 EAX99890.1 - 0.59 10.6 7.7 0.16 12.4 1.6 2.3 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Arf PF00025.21 EAX99891.1 - 1.7e-52 177.4 0.0 2e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EAX99891.1 - 6.5e-16 58.3 0.0 7.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99891.1 - 5.4e-14 52.4 0.0 7.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAX99891.1 - 4e-12 45.9 0.0 4.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX99891.1 - 3e-10 39.8 0.6 2.3e-07 30.3 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EAX99891.1 - 5.4e-05 22.7 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAX99891.1 - 6e-05 23.1 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAX99891.1 - 0.00086 18.9 0.1 0.0086 15.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EAX99891.1 - 0.013 15.3 0.0 0.067 13.0 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Thioredoxin_2 PF13098.6 EAX99891.1 - 0.033 14.7 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PEP-CTERM PF07589.11 EAX99891.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 PEP-CTERM motif PduV-EutP PF10662.9 EAX99891.1 - 0.082 12.7 0.2 11 5.7 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EAX99892.1 - 0.026 13.8 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 Septin DUF4483 PF14825.6 EAX99892.1 - 0.075 12.8 0.3 2.8 7.7 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4483) DUF913 PF06025.12 EAX99893.1 - 0.0077 15.3 1.3 0.017 14.1 1.3 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 EAX99893.1 - 0.057 12.8 1.9 0.11 11.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CNDH2_C PF16858.5 EAX99893.1 - 0.29 11.0 10.7 0.55 10.1 10.7 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Zip PF02535.22 EAX99893.1 - 0.3 10.2 1.5 0.57 9.3 1.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EAX99893.1 - 0.3 9.2 32.6 0.62 8.2 32.6 1.4 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EAX99893.1 - 0.47 9.2 13.3 0.092 11.5 9.5 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EAX99893.1 - 1.1 7.7 26.5 2.1 6.7 26.5 1.3 1 0 0 1 1 1 0 Mpp10 protein SURF2 PF05477.11 EAX99893.1 - 1.2 8.7 25.2 2.5 7.7 25.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CCDC106 PF15794.5 EAX99893.1 - 7.9 6.1 7.6 19 4.9 7.6 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EAX99893.1 - 9.6 4.4 26.9 18 3.5 26.9 1.3 1 0 0 1 1 1 0 CDC45-like protein UAA PF08449.11 EAX99894.1 - 2.4e-11 43.4 20.9 9.7e-11 41.4 20.3 1.8 1 1 1 2 2 2 1 UAA transporter family Pho86 PF11124.8 EAX99894.1 - 1.4 8.3 9.3 0.39 10.1 4.5 2.0 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Hexapep_2 PF14602.6 EAX99895.1 - 0.32 10.8 0.7 0.57 10.0 0.7 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase ASPRs PF17641.2 EAX99895.1 - 2.9 8.2 6.0 7.8 6.8 6.0 1.7 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related ABC_tran PF00005.27 EAX99898.1 - 2.6e-22 79.8 0.0 4.8e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAX99898.1 - 4.3e-11 42.5 23.3 1.2e-10 41.1 22.9 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAX99898.1 - 7.5e-07 29.3 0.6 0.0025 17.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Thioredoxin_3 PF13192.6 EAX99898.1 - 0.018 15.1 0.3 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain AAA_23 PF13476.6 EAX99898.1 - 0.026 15.0 1.6 0.061 13.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAX99898.1 - 0.04 13.8 0.4 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EAX99898.1 - 0.053 13.8 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAX99898.1 - 0.055 12.9 0.5 0.49 9.8 0.5 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EAX99898.1 - 0.072 13.5 0.2 0.18 12.2 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EAX99898.1 - 0.093 13.0 0.0 3.2 8.0 0.0 2.9 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EAX99899.1 - 8.2e-29 100.9 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAX99899.1 - 6e-11 42.7 4.8 0.00013 21.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EAX99899.1 - 5.8e-09 35.5 25.3 1e-08 34.7 25.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EAX99899.1 - 6.6e-06 25.8 0.5 1.5e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAX99899.1 - 1.4e-05 24.6 0.7 0.004 16.6 0.2 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAX99899.1 - 0.00011 22.7 2.9 0.00018 22.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAX99899.1 - 0.00026 21.0 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EAX99899.1 - 0.00038 20.3 0.4 0.00038 20.3 0.4 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EAX99899.1 - 0.006 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAX99899.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EAX99899.1 - 0.031 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAX99899.1 - 0.044 13.9 0.5 0.098 12.7 0.5 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EAX99899.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAX99899.1 - 0.078 12.6 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EAX99899.1 - 0.086 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EAX99899.1 - 0.099 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SSE PF00437.20 EAX99899.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EAX99899.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAX99899.1 - 0.14 12.1 0.1 0.45 10.4 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EAX99899.1 - 0.19 11.8 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EAX99899.1 - 0.2 11.9 0.6 6.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PDR_CDR PF06422.12 EAX99899.1 - 0.71 9.8 3.0 0.69 9.9 0.2 2.4 2 0 0 2 2 2 0 CDR ABC transporter Dynamin_N PF00350.23 EAX99899.1 - 1.6 8.8 3.2 1.5 8.9 0.4 2.2 3 0 0 3 3 2 0 Dynamin family Pox_A32 PF04665.12 EAX99901.1 - 6.3e-05 22.5 3.2 6.8e-05 22.4 2.2 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAX99901.1 - 0.0057 16.7 1.1 0.011 15.7 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAX99901.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 TPR_MLP1_2 PF07926.12 EAX99902.1 - 0.019 15.0 0.8 0.022 14.8 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAX99902.1 - 0.041 13.7 0.1 0.058 13.2 0.1 1.2 1 1 0 1 1 1 0 PaRep2a protein FAM70 PF14967.6 EAX99902.1 - 0.19 11.1 0.2 0.2 11.1 0.2 1.1 1 0 0 1 1 1 0 FAM70 protein RRM_1 PF00076.22 EAX99903.1 - 3.1e-15 55.7 0.1 5.2e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAX99903.1 - 0.0061 16.6 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 Limkain b1 DUF2777 PF10949.8 EAX99903.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) Ank_2 PF12796.7 EAX99904.1 - 2.8e-67 223.3 0.3 9.1e-21 74.3 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99904.1 - 1.4e-53 178.6 0.1 7.4e-09 36.0 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAX99904.1 - 5.5e-51 168.9 0.0 6.9e-05 23.1 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EAX99904.1 - 3.2e-47 158.0 0.1 1.3e-08 35.0 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99904.1 - 2e-40 132.1 0.0 0.00081 19.7 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat DUF4515 PF14988.6 EAX99904.1 - 0.034 14.0 2.7 0.058 13.2 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) HEAT PF02985.22 EAX99905.1 - 4.6e-05 23.3 0.1 0.0043 17.2 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 EAX99905.1 - 0.0008 19.0 0.2 0.019 14.5 0.0 3.0 3 1 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 EAX99905.1 - 0.0072 16.7 0.0 0.12 12.8 0.0 3.2 2 0 0 2 2 2 1 HEAT repeats FANCI_S2 PF14676.6 EAX99905.1 - 0.0077 16.5 0.5 0.84 9.9 0.4 3.3 2 1 0 2 2 2 1 FANCI solenoid 2 Cnd1 PF12717.7 EAX99905.1 - 0.01 15.9 5.5 0.13 12.3 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SPG48 PF14764.6 EAX99905.1 - 0.015 15.7 0.8 0.22 12.0 0.1 3.4 4 0 0 4 4 4 0 AP-5 complex subunit, vesicle trafficking TIP120 PF08623.10 EAX99905.1 - 0.019 14.7 0.3 0.2 11.4 0.0 2.6 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 EAX99905.1 - 0.026 13.1 13.4 3.2 6.2 0.0 4.3 3 2 0 3 3 3 0 Adaptin N terminal region RIX1 PF08167.12 EAX99905.1 - 0.029 14.1 1.9 28 4.4 0.0 4.8 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EAX99905.1 - 0.11 13.0 0.0 0.85 10.2 0.0 2.7 1 0 0 1 1 1 0 HEAT-like repeat alpha-hel2 PF14456.6 EAX99905.1 - 2.6 7.3 5.1 2.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Alpha-helical domain 2 Glyco_hydro_42 PF02449.15 EAX99907.1 - 0.09 12.1 0.1 0.09 12.1 0.1 1.5 2 0 0 2 2 2 0 Beta-galactosidase Ndc1_Nup PF09531.10 EAX99907.1 - 4 6.0 7.3 7 5.2 7.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_2 PF13639.6 EAX99909.1 - 1.5e-09 38.0 11.3 3.8e-09 36.7 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAX99909.1 - 1.9e-06 27.8 5.9 2.2e-06 27.6 4.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAX99909.1 - 2.9e-06 27.5 11.5 8.9e-06 25.9 11.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAX99909.1 - 7e-06 25.8 7.2 1.3e-05 24.9 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX99909.1 - 3.1e-05 23.7 8.4 6.5e-05 22.7 8.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAX99909.1 - 6e-05 22.8 11.6 6e-05 22.8 11.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX99909.1 - 0.00037 20.3 14.0 0.00038 20.3 11.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAX99909.1 - 0.0057 16.4 7.3 0.0095 15.7 4.6 2.5 2 0 0 2 2 2 1 RING-like zinc finger zinc_ribbon_16 PF17034.5 EAX99909.1 - 0.008 16.4 1.3 0.017 15.3 1.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EAX99909.1 - 0.0091 15.6 7.6 0.016 14.8 7.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EAX99909.1 - 0.032 14.2 9.0 0.087 12.8 9.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAX99909.1 - 0.094 12.8 6.7 1.4 9.0 6.7 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.9 EAX99909.1 - 0.25 11.8 1.8 3.2 8.2 0.3 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zinc-ribbons_6 PF07191.12 EAX99909.1 - 1.1 9.3 5.6 2.1 8.4 5.6 1.4 1 0 0 1 1 1 0 zinc-ribbons RINGv PF12906.7 EAX99909.1 - 3 8.1 11.1 6.6 6.9 11.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EAX99909.1 - 3.4 7.5 10.1 0.96 9.3 6.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 EAX99910.1 - 2.7e-38 130.4 0.2 1.1e-07 32.3 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99910.1 - 2.4e-30 104.2 2.2 2.6e-05 24.4 0.0 9.5 5 4 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99910.1 - 2.8e-29 97.9 0.9 0.00077 19.7 0.0 10.9 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.6 EAX99910.1 - 4.8e-23 81.2 6.2 0.00043 20.8 0.1 7.8 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAX99910.1 - 4.4e-19 68.0 0.1 0.094 13.2 0.0 8.2 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 EAX99910.1 - 0.0071 16.3 13.0 3.3 7.7 1.9 4.8 4 2 1 5 5 5 3 Domain of unknown function (DUF3447) Ank PF00023.30 EAX99912.1 - 4e-35 118.7 6.0 5.1e-07 29.9 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EAX99912.1 - 9.5e-34 115.8 10.0 2.2e-13 50.6 0.7 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99912.1 - 3e-30 104.2 4.7 1.5e-07 31.8 0.2 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99912.1 - 9.9e-27 92.7 3.3 2.6e-08 34.0 0.1 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99912.1 - 5.5e-26 87.8 5.8 8.8e-05 22.6 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat BRCT_2 PF16589.5 EAX99912.1 - 0.038 14.4 0.7 0.89 10.0 0.1 2.8 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Ank_4 PF13637.6 EAX99913.1 - 1e-19 70.6 0.8 2.7e-08 34.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99913.1 - 4.6e-17 62.4 1.7 1.8e-16 60.5 0.9 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99913.1 - 6.4e-13 48.5 0.7 0.00012 22.3 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAX99913.1 - 3.4e-12 46.3 0.0 1.5e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99913.1 - 8e-11 41.2 1.5 0.0014 19.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 EAX99914.1 - 6.1e-37 125.4 4.1 6.1e-37 125.4 4.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99914.1 - 0.0018 18.8 0.2 0.019 15.6 0.2 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99914.1 - 0.024 15.2 0.1 1.6 9.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) VPS13_C PF16909.5 EAX99915.1 - 2.5e-12 46.9 6.8 3.8e-12 46.4 2.5 2.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EAX99915.1 - 3.5e-05 23.9 0.5 3.5e-05 23.9 0.5 3.3 3 1 0 3 3 3 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 EAX99915.1 - 0.0058 16.0 0.2 0.21 10.9 0.0 3.1 2 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 SAP PF02037.27 EAX99916.1 - 2e-08 33.8 0.2 4e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 SAP domain Mu-like_Pro PF10123.9 EAX99916.1 - 0.032 13.8 1.8 0.039 13.5 1.8 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Ribosomal_L30 PF00327.20 EAX99917.1 - 3.5e-15 55.6 2.1 7.7e-15 54.5 2.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 EAX99917.1 - 6.1e-15 55.2 13.5 1.2e-14 54.3 13.5 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain MHB PF16525.5 EAX99917.1 - 0.48 10.7 2.6 0.4 11.0 1.1 1.7 2 0 0 2 2 2 0 Haemophore, haem-binding Ank_2 PF12796.7 EAX99919.1 - 1.7e-15 57.4 0.0 5.7e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99919.1 - 5.6e-15 55.2 0.0 1.9e-08 34.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99919.1 - 4.7e-11 42.6 0.0 2.8e-05 24.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EAX99919.1 - 4.2e-10 39.9 0.0 4.7e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99919.1 - 7.2e-09 35.2 0.0 0.00075 19.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF4515 PF14988.6 EAX99919.1 - 0.042 13.7 6.1 0.024 14.5 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) SnAPC_2_like PF11035.8 EAX99919.1 - 0.66 10.1 3.0 0.72 9.9 2.0 1.6 1 1 1 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Ank_2 PF12796.7 EAX99920.1 - 1.9e-92 304.0 1.9 6.7e-23 81.1 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99920.1 - 1.4e-51 171.8 0.2 2.1e-09 37.4 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAX99920.1 - 5.2e-51 170.4 0.0 2.1e-11 44.1 0.0 5.2 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAX99920.1 - 1.4e-47 158.1 0.0 1.1e-05 25.6 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAX99920.1 - 1e-39 130.0 0.0 0.00043 20.5 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat DUF4515 PF14988.6 EAX99920.1 - 0.045 13.6 4.5 0.032 14.1 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) DUF2452 PF10504.9 EAX99921.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) CBP4 PF07960.11 EAX99921.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 CBP4 Med4 PF10018.9 EAX99922.1 - 0.0015 18.2 2.8 0.0018 18.0 2.8 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.21 EAX99922.1 - 0.0017 18.4 3.4 0.0017 18.4 3.4 1.5 1 1 0 1 1 1 1 bZIP transcription factor APG6_N PF17675.1 EAX99922.1 - 0.0037 17.8 4.4 0.0044 17.5 4.4 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region DivIC PF04977.15 EAX99922.1 - 0.0041 16.9 3.4 0.0041 16.9 3.4 1.6 2 0 0 2 2 1 1 Septum formation initiator TMCO5 PF14992.6 EAX99922.1 - 0.0067 16.0 6.3 0.0067 16.0 6.3 1.4 1 1 0 1 1 1 1 TMCO5 family GrpE PF01025.19 EAX99922.1 - 0.0071 16.0 0.8 0.0083 15.8 0.8 1.0 1 0 0 1 1 1 1 GrpE KIAA1430 PF13879.6 EAX99922.1 - 0.012 16.4 3.7 0.015 16.1 3.7 1.1 1 0 0 1 1 1 0 KIAA1430 homologue Shugoshin_N PF07558.11 EAX99922.1 - 0.012 15.5 2.5 0.022 14.6 2.4 1.5 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF4337 PF14235.6 EAX99922.1 - 0.022 14.9 0.1 0.023 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GPS2_interact PF15784.5 EAX99922.1 - 0.023 15.1 3.4 0.026 14.9 3.4 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CENP-H PF05837.12 EAX99922.1 - 0.023 15.1 3.7 0.028 14.8 3.7 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 EAX99922.1 - 0.04 14.5 1.0 0.056 14.1 1.0 1.3 1 0 0 1 1 1 0 SlyX DUF724 PF05266.14 EAX99922.1 - 0.057 13.2 3.6 0.067 13.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 EAX99922.1 - 0.062 13.7 8.2 0.087 13.3 8.2 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF2207 PF09972.9 EAX99922.1 - 0.064 12.0 0.6 0.073 11.8 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_UL6 PF01763.16 EAX99922.1 - 0.071 11.6 0.9 0.078 11.5 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Paralemmin PF03285.15 EAX99922.1 - 0.088 12.4 2.2 0.1 12.1 2.2 1.1 1 0 0 1 1 1 0 Paralemmin YabA PF06156.13 EAX99922.1 - 0.11 13.2 1.5 0.12 13.0 1.5 1.1 1 0 0 1 1 1 0 Initiation control protein YabA RF-1 PF00472.20 EAX99922.1 - 0.13 12.2 2.3 0.16 11.9 2.3 1.1 1 0 0 1 1 1 0 RF-1 domain NatB_MDM20 PF09797.9 EAX99923.1 - 6.4e-08 31.9 15.0 0.0001 21.4 1.0 4.5 2 1 1 5 5 5 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EAX99923.1 - 1.9e-07 31.5 6.8 0.011 16.2 0.6 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAX99923.1 - 0.0046 17.7 0.2 12 7.1 0.0 4.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAX99923.1 - 0.052 12.7 0.1 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat PPR_2 PF13041.6 EAX99923.1 - 0.067 13.4 0.1 0.32 11.2 0.1 2.2 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 EAX99923.1 - 0.47 10.8 1.9 8.3 6.9 0.0 3.8 3 0 0 3 3 3 0 PPR repeat ANAPC3 PF12895.7 EAX99923.1 - 6.9 7.0 16.0 1.2 9.4 0.7 4.3 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RloB PF13707.6 EAX99923.1 - 7.7 6.7 9.7 3 8.0 0.6 2.9 3 0 0 3 3 3 0 RloB-like protein Adaptin_N PF01602.20 EAX99924.1 - 5.3e-74 249.7 5.1 7.9e-74 249.1 5.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAX99924.1 - 4.8e-07 29.9 3.1 2e-05 24.7 0.1 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAX99924.1 - 0.0072 16.5 0.1 27 5.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 EAX99924.1 - 0.05 13.2 0.6 0.13 11.8 0.6 1.7 1 0 0 1 1 1 0 CLASP N terminal Rep_fac-A_C PF08646.10 EAX99925.1 - 0.039 13.7 1.0 7.3 6.3 0.9 2.2 1 1 1 2 2 2 0 Replication factor-A C terminal domain Mut7-C PF01927.16 EAX99925.1 - 0.11 12.5 0.8 0.17 12.0 0.8 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain DZR PF12773.7 EAX99925.1 - 0.14 12.2 2.8 0.69 10.0 2.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 EAX99925.1 - 0.15 11.7 1.9 2.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 EAX99925.1 - 0.18 11.8 2.0 0.68 9.9 2.0 1.9 1 1 0 1 1 1 0 zinc-ribbons Rubredoxin_2 PF18073.1 EAX99925.1 - 0.31 10.8 4.2 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain TackOD1 PF18551.1 EAX99925.1 - 0.86 9.3 4.3 3.1 7.4 1.2 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 TM231 PF10149.9 EAX99927.1 - 8.3e-11 41.8 7.7 4.7e-06 26.2 1.7 2.2 2 0 0 2 2 2 2 Transmembrane protein 231 DUF3561 PF12084.8 EAX99927.1 - 2.3 8.3 7.6 4.5 7.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Ank_2 PF12796.7 EAX99928.1 - 1.5e-46 156.9 0.0 9.8e-16 58.1 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99928.1 - 3.6e-26 91.2 0.0 3.3e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAX99928.1 - 4.1e-25 87.5 0.2 3.4e-07 30.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAX99928.1 - 1.3e-22 79.2 0.0 3.7e-05 24.0 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAX99928.1 - 4.9e-20 69.5 0.0 0.0008 19.7 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat MA3 PF02847.17 EAX99928.1 - 0.017 15.1 0.1 24 5.0 0.0 3.8 3 2 1 4 4 4 0 MA3 domain KAP PF05804.12 EAX99929.1 - 0.0037 15.5 5.2 0.005 15.0 1.3 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) KRAP_IP3R_bind PF14722.6 EAX99929.1 - 0.076 12.8 0.2 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DUF3361 PF11841.8 EAX99929.1 - 0.6 10.0 8.1 0.19 11.7 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) S1-P1_nuclease PF02265.16 EAX99930.1 - 7.7e-14 52.1 0.0 1.1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease HECT PF00632.25 EAX99931.1 - 8.7e-54 183.1 1.5 8.7e-54 183.1 1.5 2.3 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) ANAPC2 PF08672.11 EAX99931.1 - 0.069 13.7 1.4 12 6.5 0.1 3.4 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 HOOK PF05622.12 EAX99932.1 - 0.0067 14.6 22.0 0.008 14.4 22.0 1.1 1 0 0 1 1 1 1 HOOK protein Ly49 PF08391.10 EAX99932.1 - 0.019 15.4 5.7 0.019 15.4 5.7 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TPR_MLP1_2 PF07926.12 EAX99932.1 - 0.2 11.8 31.9 7.8 6.6 3.4 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EAX99932.1 - 0.31 11.1 11.1 0.069 13.2 2.8 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 EAX99932.1 - 0.38 10.8 22.3 1.1 9.3 5.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4574 PF15141.6 EAX99932.1 - 0.54 10.2 4.1 1.4 8.9 4.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF3450 PF11932.8 EAX99932.1 - 0.56 9.5 20.8 3.7 6.8 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec8_exocyst PF04048.14 EAX99932.1 - 0.67 9.8 13.9 1.2 9.0 3.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PHM7_cyt PF14703.6 EAX99932.1 - 0.73 10.0 11.8 1.1 9.5 11.8 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Spc7 PF08317.11 EAX99932.1 - 1.1 8.0 26.6 0.66 8.8 18.1 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Nup88 PF10168.9 EAX99932.1 - 1.4 6.7 21.4 1.7 6.4 21.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Chibby PF14645.6 EAX99932.1 - 1.9 8.9 19.2 1.4 9.4 1.7 3.0 1 1 2 3 3 3 0 Chibby family MPS2 PF17060.5 EAX99932.1 - 2 7.6 20.1 0.82 8.9 6.4 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 UPF0242 PF06785.11 EAX99932.1 - 2.2 8.4 28.7 0.37 10.9 11.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tho2 PF11262.8 EAX99932.1 - 2.7 7.1 19.0 0.052 12.7 7.5 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Snapin_Pallidin PF14712.6 EAX99932.1 - 3.1 8.3 18.3 0.15 12.5 7.0 2.9 2 2 1 3 3 3 0 Snapin/Pallidin V_ATPase_I PF01496.19 EAX99932.1 - 3.2 5.6 14.8 4.4 5.1 14.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 EAX99932.1 - 6.5 7.0 25.0 1.8 8.8 19.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 EAX99932.1 - 9.8 5.4 14.8 54 3.0 14.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Amidinotransf PF02274.17 EAX99933.1 - 0.0013 17.9 0.2 0.026 13.6 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase LRR_6 PF13516.6 EAX99934.1 - 1e-27 93.8 39.1 0.00027 20.8 0.2 12.1 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.7 EAX99934.1 - 6.9e-08 32.7 25.0 0.00079 19.8 0.1 7.4 5 3 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAX99934.1 - 5.1e-07 29.4 10.7 68 4.6 0.0 9.7 11 0 0 11 11 11 0 Leucine Rich Repeat CALCOCO1 PF07888.11 EAX99934.1 - 0.002 17.1 17.7 0.0034 16.3 17.7 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like LRR_8 PF13855.6 EAX99934.1 - 0.0031 17.3 21.1 0.065 13.0 4.7 7.1 4 2 2 6 6 6 1 Leucine rich repeat WASH-7_C PF14746.6 EAX99934.1 - 0.015 15.0 1.4 0.015 15.0 1.4 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Spc7 PF08317.11 EAX99934.1 - 1.5 7.6 23.2 1.2 8.0 9.8 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF5300 PF17224.3 EAX99934.1 - 2.6 8.3 13.4 2.6 8.4 0.1 4.5 4 1 0 5 5 5 0 Domain of unknown function (DUF5300) Sec20 PF03908.13 EAX99935.1 - 1e-05 25.3 0.8 1e-05 25.3 0.8 2.4 3 0 0 3 3 3 1 Sec20 BORCS8 PF10167.9 EAX99935.1 - 0.094 12.7 5.3 0.39 10.7 0.5 2.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 CENP-H PF05837.12 EAX99935.1 - 1.4 9.4 16.0 5.2 7.5 2.9 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 EAX99935.1 - 2 8.5 9.7 0.31 11.1 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3139 PF11337.8 EAX99935.1 - 2.5 8.8 10.8 1.6 9.4 1.6 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3139) Imm5 PF14423.6 EAX99935.1 - 9.7 6.4 11.8 3.2 7.9 0.1 3.2 2 1 2 4 4 4 0 Immunity protein Imm5 DUF3447 PF11929.8 EAX99936.1 - 3.2e-28 97.5 3.2 3.2e-28 97.5 3.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAX99936.1 - 0.0071 16.9 0.0 0.26 11.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) EKAL PF17986.1 EAX99936.1 - 0.11 12.6 1.6 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain Ank PF00023.30 EAX99937.1 - 9.8e-08 32.1 0.4 0.00031 21.1 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAX99937.1 - 3.3e-07 30.7 0.1 0.0092 16.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99937.1 - 1.5e-06 28.7 0.1 1.8e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99937.1 - 2.5e-06 27.4 0.1 0.0026 18.1 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAX99937.1 - 1.2e-05 25.5 0.1 2.4e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) JAB PF01398.21 EAX99938.1 - 1.8e-28 98.9 0.0 3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EAX99938.1 - 1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 EAX99938.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Renin_r PF07850.14 EAX99939.1 - 0.078 13.6 1.0 0.21 12.2 0.2 2.1 2 1 0 2 2 2 0 Renin receptor-like protein G10 PF01125.17 EAX99939.1 - 5.1 6.9 6.5 82 2.9 3.9 3.0 2 1 0 2 2 2 0 G10 protein EMC3_TMCO1 PF01956.16 EAX99941.1 - 0.042 13.6 4.8 0.062 13.0 4.1 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2203 PF09969.9 EAX99941.1 - 0.088 13.5 4.6 0.092 13.5 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ISG65-75 PF11727.8 EAX99941.1 - 0.21 10.8 13.5 0.094 11.9 9.1 2.0 2 0 0 2 2 2 0 Invariant surface glycoprotein YtxH PF12732.7 EAX99941.1 - 1.4 9.5 6.9 3.8 8.1 6.9 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF4407 PF14362.6 EAX99941.1 - 1.6 8.0 9.0 2.4 7.4 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1090 PF06476.12 EAX99941.1 - 1.7 8.8 17.9 1.3 9.2 7.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1090) Cep57_MT_bd PF06657.13 EAX99941.1 - 2.7 8.5 8.5 0.64 10.5 0.7 3.4 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Med26 PF08711.11 EAX99945.1 - 5.3e-07 29.6 1.7 2.7e-06 27.3 0.3 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ras PF00071.22 EAX99947.1 - 1.2e-32 112.7 0.0 1.4e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99947.1 - 1.4e-17 64.0 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99947.1 - 6.5e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAX99947.1 - 2e-05 24.7 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99947.1 - 0.0034 16.8 0.0 0.0066 15.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAX99947.1 - 0.0096 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAX99947.1 - 0.015 15.2 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 EAX99947.1 - 0.017 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EAX99947.1 - 0.017 15.4 0.0 0.083 13.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EAX99947.1 - 0.025 15.0 0.0 0.037 14.5 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EAX99947.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAX99947.1 - 0.04 14.3 0.1 0.088 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EAX99947.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAX99947.1 - 0.053 13.0 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EAX99947.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 EAX99947.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EAX99947.1 - 0.28 10.3 1.9 11 5.0 0.9 2.8 1 1 1 2 2 2 0 G-protein alpha subunit Ank_4 PF13637.6 EAX99948.1 - 5.4e-19 68.3 0.1 2.1e-11 44.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99948.1 - 2.7e-14 52.9 0.0 1.4e-07 31.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAX99948.1 - 1e-12 48.5 0.1 1.5e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAX99948.1 - 3.6e-11 43.1 0.1 5.9e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99948.1 - 6.8e-11 41.4 0.2 6.5e-07 29.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Arf PF00025.21 EAX99949.1 - 2.1e-40 138.0 0.4 2.4e-40 137.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EAX99949.1 - 2.3e-13 50.1 0.0 2.7e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAX99949.1 - 2.4e-11 43.9 0.0 3.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAX99949.1 - 3.7e-11 43.1 0.3 6.2e-11 42.4 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAX99949.1 - 1.1e-07 31.4 0.5 1.4e-07 31.2 0.5 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAX99949.1 - 2.9e-06 26.7 0.8 3.7e-05 23.1 0.3 2.5 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 EAX99949.1 - 8.3e-06 25.5 0.4 0.0026 17.3 0.1 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EAX99949.1 - 1.6e-05 24.6 0.9 0.0004 20.2 0.9 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EAX99949.1 - 0.00027 21.2 0.0 0.001 19.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain NOG1 PF06858.14 EAX99949.1 - 0.00044 20.0 0.3 0.0015 18.2 0.2 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 EAX99949.1 - 0.00094 19.7 0.2 0.0092 16.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 EAX99949.1 - 0.0012 18.4 3.5 0.0087 15.6 3.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 EAX99949.1 - 0.0029 17.8 0.0 0.0049 17.0 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EAX99949.1 - 0.0049 17.1 0.1 0.0077 16.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1_Xtn PF16897.5 EAX99949.1 - 0.0074 16.3 0.6 0.013 15.5 0.6 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EAX99949.1 - 0.0082 16.7 0.6 0.02 15.4 0.6 1.7 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 EAX99949.1 - 0.0091 15.9 0.1 0.7 9.8 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 EAX99949.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EAX99949.1 - 0.014 15.0 0.7 0.95 9.0 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAX99949.1 - 0.021 14.4 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAX99949.1 - 0.032 14.6 0.0 0.049 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EAX99949.1 - 0.043 13.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Dynamin family KTI12 PF08433.10 EAX99949.1 - 0.045 13.2 0.2 0.17 11.3 0.0 1.9 1 1 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EAX99949.1 - 0.05 13.5 0.0 0.086 12.8 0.0 1.4 1 1 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 EAX99949.1 - 0.11 12.2 0.2 2.8 7.7 0.0 2.3 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EAX99949.1 - 0.18 11.3 0.4 0.4 10.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EAX99949.1 - 0.46 9.4 2.6 4.7 6.1 0.0 2.7 2 2 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB INCENP_ARK-bind PF03941.15 EAX99950.1 - 2.9e-14 52.7 0.1 5.6e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF4108 PF13390.6 EAX99951.1 - 1.7e-62 209.6 6.4 1.8e-62 209.5 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA_11 PF13086.6 EAX99953.1 - 0.0034 17.2 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAX99953.1 - 0.0071 16.6 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EAX99953.1 - 0.019 14.4 0.1 0.023 14.1 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAX99953.1 - 0.025 14.6 0.2 0.033 14.2 0.2 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EAX99953.1 - 0.034 13.7 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAX99953.1 - 0.04 14.3 0.1 0.057 13.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAX99953.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein KilA-N PF04383.13 EAX99955.1 - 1.5e-22 79.5 0.1 1.9e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAX99955.1 - 0.0095 15.9 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin zf-MIZ PF02891.20 EAX99959.1 - 2e-19 69.0 1.5 4.1e-19 68.1 1.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAX99959.1 - 0.0011 18.8 0.4 0.0011 18.8 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 EAX99960.1 - 8.2e-54 182.7 0.0 1.4e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAX99960.1 - 5.8e-25 88.0 0.0 1.3e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAX99960.1 - 1.2e-06 28.0 0.0 0.0065 15.8 0.0 2.3 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 EAX99960.1 - 0.00047 20.2 0.0 0.0064 16.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAX99960.1 - 0.0053 16.4 0.4 0.018 14.7 0.1 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 EAX99960.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_topoisoIV PF00521.20 EAX99960.1 - 0.0098 14.8 3.2 0.17 10.7 1.1 2.1 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A ABC1 PF03109.16 EAX99960.1 - 0.016 15.4 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 EAX99960.1 - 0.062 12.9 1.2 1.7 8.2 0.0 2.5 1 1 0 2 2 2 0 RIO1 family Proteasome PF00227.26 EAX99961.1 - 3.3e-33 114.8 0.0 3.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAX99961.1 - 1.5e-09 37.3 0.0 2.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RFX5_N PF18326.1 EAX99961.1 - 0.079 12.7 0.5 1.5 8.6 0.2 2.8 3 0 0 3 3 3 0 RFX5 N-terminal domain Fes1 PF08609.10 EAX99962.1 - 6.6e-08 33.3 1.9 5.1e-07 30.5 0.6 2.5 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Atx10homo_assoc PF09759.9 EAX99962.1 - 0.021 14.8 0.0 0.06 13.4 0.0 1.9 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 EAX99962.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 EAX99962.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Arm PF00514.23 EAX99962.1 - 0.12 12.4 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAX99962.1 - 0.2 12.2 0.0 0.58 10.7 0.0 1.8 1 0 0 1 1 1 0 HEAT-like repeat Nicastrin PF05450.15 EAX99963.1 - 2.6e-26 92.5 0.2 4.1e-26 91.9 0.2 1.3 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 EAX99963.1 - 3.1e-14 53.3 0.0 9.9e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Nicastrin small lobe Peptidase_M28 PF04389.17 EAX99963.1 - 3.2e-06 27.0 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Csm1_N PF18504.1 EAX99964.1 - 0.0037 17.6 7.1 0.0037 17.6 7.1 7.3 4 2 3 8 8 8 1 Csm1 N-terminal domain TMV_coat PF00721.21 EAX99964.1 - 0.054 13.3 0.2 0.054 13.3 0.2 3.1 3 1 0 3 3 3 0 Virus coat protein (TMV like) HrpB7 PF09486.10 EAX99964.1 - 0.83 10.0 11.8 0.78 10.1 8.4 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Beta-Casp PF10996.8 EAX99965.1 - 0.01 16.1 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 Beta-Casp domain ELP6 PF09807.9 EAX99965.1 - 0.016 14.7 0.7 0.26 10.7 0.1 2.0 1 1 1 2 2 2 0 Elongation complex protein 6 HTH_40 PF14493.6 EAX99965.1 - 0.018 15.5 0.4 0.79 10.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 EAX99965.1 - 0.035 14.2 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Peptidase_S51 PF03575.17 EAX99965.1 - 0.047 13.3 0.2 0.1 12.2 0.2 1.6 1 1 0 1 1 1 0 Peptidase family S51 DUF4108 PF13390.6 EAX99966.1 - 4.7e-64 214.6 6.9 5.2e-64 214.5 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAX99966.1 - 0.12 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide PcfK PF14058.6 EAX99967.1 - 0.062 13.6 10.4 0.088 13.1 10.4 1.4 1 1 0 1 1 1 0 PcfK-like protein GGDEF PF00990.21 EAX99967.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DUF2897 PF11446.8 EAX99967.1 - 7.6 6.5 6.5 17 5.3 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.6 EAX99968.1 - 3.4e-05 24.1 0.2 0.00024 21.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAX99968.1 - 4.7e-05 23.2 0.2 0.33 10.7 0.1 2.6 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAX99968.1 - 0.00011 22.2 2.7 0.00022 21.3 2.7 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAX99968.1 - 0.00058 19.7 0.0 0.00097 18.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pox_A32 PF04665.12 EAX99968.1 - 0.0006 19.3 2.2 0.0006 19.3 2.2 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_11 PF13086.6 EAX99968.1 - 0.0015 18.4 0.6 0.0046 16.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAX99968.1 - 0.0023 17.6 0.5 0.014 15.0 0.2 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAX99968.1 - 0.015 15.6 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAX99968.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAX99968.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EAX99968.1 - 0.1 13.1 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1827 PF08860.10 EAX99968.1 - 0.18 12.0 4.1 4.4 7.6 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) zf-C3HC4_3 PF13920.6 EAX99970.1 - 1.7e-09 37.4 5.7 2.8e-09 36.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAX99970.1 - 2.9e-08 33.9 9.4 5.8e-08 32.9 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAX99970.1 - 7.9e-08 32.0 9.4 1.7e-07 30.9 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAX99970.1 - 3.4e-07 30.0 8.3 7.1e-07 29.0 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAX99970.1 - 2.6e-06 27.2 8.0 4.1e-06 26.6 7.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAX99970.1 - 7.5e-06 25.9 4.9 7.5e-06 25.9 4.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAX99970.1 - 1.5e-05 24.8 10.0 3.9e-05 23.5 10.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAX99970.1 - 0.00041 20.5 11.4 0.001 19.1 11.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EAX99970.1 - 0.0037 17.5 10.2 0.0096 16.2 10.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAX99970.1 - 0.014 15.4 3.5 0.03 14.4 3.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EAX99970.1 - 0.19 11.6 9.5 0.47 10.3 8.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EAX99970.1 - 1.2 8.9 12.5 0.27 11.0 6.6 2.6 1 1 1 2 2 2 0 RING-like zinc finger Elf1 PF05129.13 EAX99970.1 - 1.2 9.2 6.3 4.3 7.5 6.3 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Thioredoxin PF00085.20 EAX99971.1 - 9.3e-13 48.1 0.0 3.5e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EAX99971.1 - 0.0014 18.8 0.0 0.0087 16.3 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 EAX99971.1 - 0.0023 18.3 0.2 0.029 14.8 0.0 2.6 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 EAX99971.1 - 0.0036 17.6 0.0 0.075 13.4 0.0 2.9 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.6 EAX99971.1 - 0.024 14.8 0.3 0.23 11.6 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin PTR PF12789.7 EAX99972.1 - 8.9e-120 390.8 93.2 4.2e-32 110.0 15.8 5.7 4 2 4 8 8 8 5 Phage tail repeat like DUF4116 PF13475.6 EAX99972.1 - 0.028 14.1 0.4 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) PBP5_C PF07943.13 EAX99972.1 - 0.085 13.1 1.4 0.44 10.8 0.0 2.8 3 0 0 3 3 3 0 Penicillin-binding protein 5, C-terminal domain PH_TFIIH PF08567.11 EAX99972.1 - 8 6.9 9.6 74 3.8 0.1 4.7 1 1 5 6 6 6 0 TFIIH p62 subunit, N-terminal domain DUF1493 PF07377.12 EAX99973.1 - 0.025 15.0 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAX99973.1 - 0.27 11.3 2.0 9.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein GAS PF13851.6 EAX99974.1 - 0.0025 17.2 33.4 0.0025 17.2 33.4 35.1 2 2 31 36 36 36 10 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAX99974.1 - 0.0031 17.5 19.6 0.0031 17.5 19.6 37.3 5 2 35 41 41 41 21 Laminin Domain II LRR_5 PF13306.6 EAX99975.1 - 1.3e-75 251.5 67.6 1.6e-17 63.6 3.4 8.7 3 3 4 8 8 8 7 BspA type Leucine rich repeat region (6 copies) DUF5305 PF17231.2 EAX99976.1 - 0.03 13.7 0.7 0.061 12.7 0.2 1.6 1 1 0 2 2 2 0 Family of unknown function (DUF5305) RasGEF PF00617.19 EAX99977.1 - 4.5e-32 111.7 1.0 1.9e-31 109.7 1.0 2.1 1 0 0 1 1 1 1 RasGEF domain INTS5_N PF14837.6 EAX99977.1 - 0.00051 19.7 2.0 0.00084 19.0 0.4 2.1 2 0 0 2 2 2 1 Integrator complex subunit 5 N-terminus Myb_DNA-binding PF00249.31 EAX99978.1 - 8.4e-14 51.5 0.1 5.2e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAX99978.1 - 3.8e-13 49.5 4.4 2e-09 37.6 1.7 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain QueF PF14489.6 EAX99978.1 - 0.0039 17.3 0.2 0.17 12.0 0.0 2.4 1 1 1 2 2 2 1 QueF-like protein Myb_DNA-bind_7 PF15963.5 EAX99978.1 - 0.006 16.5 0.4 0.006 16.5 0.4 2.8 2 2 1 3 3 3 1 Myb DNA-binding like DUF4768 PF15989.5 EAX99978.1 - 0.028 14.4 1.3 0.048 13.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4768) Atg29_N PF18388.1 EAX99978.1 - 0.1 12.5 0.2 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Atg29 N-terminal domain GhoS PF11080.8 EAX99980.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Endoribonuclease GhoS MOR2-PAG1_C PF14225.6 EAX99981.1 - 0.0039 17.1 1.9 0.64 9.8 0.0 3.9 4 1 0 4 4 4 1 Cell morphogenesis C-terminal Telomere_reg-2 PF10193.9 EAX99981.1 - 0.011 16.1 2.9 0.38 11.2 0.1 4.6 4 1 0 4 4 4 0 Telomere length regulation protein Retrotran_gag_2 PF14223.6 EAX99981.1 - 0.032 13.9 0.4 0.45 10.2 0.0 3.2 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type IFRD PF05004.13 EAX99981.1 - 0.039 13.0 2.0 8.3 5.4 0.2 4.2 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) VPS28 PF03997.12 EAX99981.1 - 0.062 13.0 0.1 0.062 13.0 0.1 4.0 4 1 0 5 5 5 0 VPS28 protein SecE PF00584.20 EAX99981.1 - 0.23 11.4 1.6 0.41 10.6 0.0 2.4 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex U3snoRNP10 PF12397.8 EAX99981.1 - 3.8 7.9 8.7 14 6.1 0.0 4.3 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 TTL PF03133.15 EAX99982.1 - 3.9e-46 157.5 0.1 5.9e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAX99982.1 - 3.1e-13 49.6 0.0 1e-05 24.9 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAX99982.1 - 4.6e-09 35.9 0.0 0.0018 17.6 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAX99982.1 - 3.5e-05 23.9 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.16 EAX99982.1 - 0.013 14.9 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain OHCU_decarbox PF09349.10 EAX99982.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 OHCU decarboxylase TMP PF05017.14 EAX99983.1 - 0.21 12.3 2.1 15 6.8 0.2 3.6 3 0 0 3 3 3 0 TMP repeat Meiosis_expr PF15163.6 EAX99984.1 - 0.042 14.5 0.7 0.07 13.8 0.2 1.6 2 0 0 2 2 2 0 Meiosis-expressed Spo12 PF05032.12 EAX99984.1 - 3.5 7.6 12.4 0.11 12.5 2.3 3.1 4 1 0 4 4 4 0 Spo12 family ANAPC4_WD40 PF12894.7 EAX99985.1 - 0.014 15.7 0.0 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4119 PF13494.6 EAX99985.1 - 0.096 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Ank_4 PF13637.6 EAX99987.1 - 9.6e-10 38.8 0.3 8.7e-05 23.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99987.1 - 8.9e-08 32.6 0.1 1.2e-06 29.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAX99987.1 - 3.8e-06 26.8 0.2 0.061 13.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EAX99987.1 - 2.1e-05 24.7 0.0 0.003 17.9 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4974 PF16344.5 EAX99987.1 - 0.01 15.8 2.0 0.077 13.0 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) CTD_bind PF04818.13 EAX99987.1 - 0.024 15.4 0.0 0.08 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase II-binding domain. YolD PF08863.10 EAX99987.1 - 0.25 11.4 2.6 4.5 7.4 0.1 2.5 1 1 0 2 2 2 0 YolD-like protein DUF445 PF04286.12 EAX99988.1 - 0.011 15.6 8.3 0.1 12.4 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) AP1AR PF15745.5 EAX99988.1 - 0.013 15.2 3.9 0.016 14.8 3.9 1.0 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Sulphotransf PF09037.10 EAX99988.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase ALMT PF11744.8 EAX99988.1 - 0.49 9.2 4.6 0.5 9.1 4.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lys-AminoMut_A PF09043.11 EAX99988.1 - 1.1 7.6 5.0 1.6 7.1 5.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF2533 PF10752.9 EAX99988.1 - 1.6 9.3 6.1 0.65 10.5 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2533) Exonuc_VII_L PF02601.15 EAX99988.1 - 1.9 8.0 8.0 2.6 7.5 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.6 EAX99988.1 - 5.9 7.3 21.8 16 5.9 3.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) PTR PF12789.7 EAX99989.1 - 2.7e-24 85.0 11.0 4.4e-23 81.1 5.2 5.4 6 1 0 6 6 6 2 Phage tail repeat like DUF4116 PF13475.6 EAX99989.1 - 0.037 13.8 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) YmaF PF12788.7 EAX99989.1 - 0.18 12.4 18.7 1.2 9.7 0.3 4.4 3 2 0 4 4 4 0 YmaF family DUF1493 PF07377.12 EAX99990.1 - 0.073 13.5 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAX99991.1 - 0.12 13.0 7.9 6.3 7.9 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAX99991.1 - 5.3 7.0 8.4 5.6 6.9 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIR PF02815.19 EAX99992.1 - 1.8e-10 41.0 0.8 7.8e-08 32.4 0.4 2.5 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 EAX99992.1 - 8e-05 21.9 0.5 0.035 13.3 0.1 2.1 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor Ank_2 PF12796.7 EAX99993.1 - 6.6e-22 77.9 1.2 1.2e-14 54.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99993.1 - 2.1e-20 72.8 0.2 4.4e-10 39.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAX99993.1 - 8e-18 64.0 0.0 1.1e-07 32.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX99993.1 - 1.2e-16 60.6 0.3 3.8e-11 43.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99993.1 - 7e-15 53.7 0.2 4.1e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAX99994.1 - 4.9e-38 128.9 8.5 4.9e-38 128.9 8.5 3.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99994.1 - 0.017 15.7 0.3 0.24 12.0 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99995.1 - 3.4e-21 75.3 0.3 2.2e-11 44.0 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAX99995.1 - 1.3e-15 57.7 1.5 1.9e-15 57.2 1.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAX99995.1 - 4.5e-14 52.2 0.1 8.5e-07 29.1 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAX99995.1 - 5.5e-14 52.1 0.1 1.9e-06 28.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAX99995.1 - 3.2e-12 45.5 0.1 2.2e-05 24.5 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3895 PF13034.6 EAX99995.1 - 0.0051 16.8 0.3 0.29 11.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3895) CDC37_M PF08565.11 EAX99995.1 - 0.0089 16.0 0.1 0.064 13.2 0.0 1.9 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain Stap_Strp_toxin PF01123.20 EAX99995.1 - 0.029 15.2 0.2 0.038 14.8 0.2 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3447 PF11929.8 EAX99996.1 - 4.3e-40 135.5 6.0 4.3e-40 135.5 6.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAX99996.1 - 0.00031 21.3 0.2 0.0063 17.1 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAX99996.1 - 0.02 15.4 0.3 19 6.0 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ras PF00071.22 EAX99997.1 - 2.3e-42 144.4 0.0 4.1e-42 143.5 0.0 1.4 1 1 1 2 2 2 1 Ras family Roc PF08477.13 EAX99997.1 - 1.1e-33 115.9 0.0 1.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAX99997.1 - 1.4e-15 57.2 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAX99997.1 - 9.2e-06 25.3 0.0 9.1e-05 22.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAX99997.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAX99997.1 - 9.2e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAX99997.1 - 0.0015 18.4 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 EAX99997.1 - 0.0064 15.9 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 EAX99997.1 - 0.034 13.7 0.0 0.66 9.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EAX99997.1 - 0.069 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EAX99997.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Amidohydro_1 PF01979.20 EAX99999.1 - 2.9e-73 247.1 0.0 3.4e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAX99999.1 - 1.5e-10 41.1 0.0 4.1e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EAX99999.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Rad60-SLD PF11976.8 EAY00001.1 - 0.0097 15.7 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAY00001.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Baculo_11_kDa PF06143.11 EAY00002.1 - 0.0036 16.8 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Baculovirus 11 kDa family TMEM132D_C PF15706.5 EAY00002.1 - 0.0071 16.1 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Amnionless PF14828.6 EAY00002.1 - 0.0077 15.1 0.0 0.0082 15.0 0.0 1.0 1 0 0 1 1 1 1 Amnionless DUF5305 PF17231.2 EAY00002.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Chordopox_A13L PF05961.11 EAY00002.1 - 0.012 15.8 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein OAD_gamma PF04277.13 EAY00002.1 - 0.015 15.9 0.0 0.019 15.6 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pilin_N PF07790.11 EAY00002.1 - 0.025 15.5 0.0 0.029 15.3 0.0 1.1 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Tetraspanin PF00335.20 EAY00002.1 - 0.026 14.2 0.0 0.027 14.2 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family Cytochrom_B_N_2 PF13631.6 EAY00002.1 - 0.036 14.1 0.1 0.037 14.0 0.1 1.0 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB S1FA PF04689.13 EAY00002.1 - 0.074 13.2 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 DNA binding protein S1FA MacB_PCD PF12704.7 EAY00002.1 - 0.078 13.3 0.0 0.078 13.3 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain BatD PF13584.6 EAY00002.1 - 0.087 11.6 0.0 0.092 11.5 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance ECSCR PF15820.5 EAY00002.1 - 0.088 12.6 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EMC3_TMCO1 PF01956.16 EAY00002.1 - 0.089 12.5 0.0 0.095 12.4 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF898 PF05987.13 EAY00002.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SARAF PF06682.12 EAY00002.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3149 PF11346.8 EAY00002.1 - 0.49 10.0 5.2 0.67 9.6 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3149) Adenine_glyco PF03352.13 EAY00003.1 - 5.6e-75 251.0 0.1 6.3e-75 250.8 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase DUF5035 PF16438.5 EAY00003.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) HhH-GPD PF00730.25 EAY00003.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PTS_IIA PF02255.16 EAY00004.1 - 0.02 14.9 0.4 0.079 13.0 0.1 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit ADK PF00406.22 EAY00005.1 - 1.8e-07 31.4 0.0 3e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAY00005.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain FH2 PF02181.23 EAY00006.1 - 8.7e-75 252.2 1.2 8.7e-75 252.2 1.2 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EAY00006.1 - 1.4e-13 50.9 1.3 1.4e-13 50.9 1.3 3.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Pro-kuma_activ PF09286.11 EAY00006.1 - 0.28 11.5 1.0 2.3 8.5 0.3 2.5 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain Exonuc_VII_L PF02601.15 EAY00006.1 - 0.44 10.1 9.0 0.1 12.2 0.9 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3130 PF11328.8 EAY00006.1 - 0.63 10.3 4.0 13 6.1 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 DUF3447 PF11929.8 EAY00007.1 - 1.3e-40 137.2 1.9 1.3e-40 137.2 1.9 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00007.1 - 6.3e-08 33.1 0.1 0.00098 19.7 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00007.1 - 1.9e-07 31.5 1.6 0.002 18.6 0.0 4.1 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00007.1 - 0.00011 22.4 0.0 0.078 13.3 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00007.1 - 0.0047 17.3 0.8 27 5.8 0.0 4.9 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 EAY00007.1 - 0.049 14.1 0.0 27 5.4 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Toxin_R_bind_C PF07951.12 EAY00009.1 - 0.074 12.7 2.5 0.048 13.3 1.0 1.5 2 0 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding YfbU PF03887.14 EAY00009.1 - 0.095 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 YfbU domain Antimicrobial_8 PF08103.11 EAY00009.1 - 8.1 6.8 6.3 1.5 9.2 0.6 2.6 2 0 0 2 2 2 0 Uperin family UCH PF00443.29 EAY00011.1 - 3.9e-37 128.2 0.5 5.9e-37 127.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAY00011.1 - 2.7e-24 85.3 21.0 1.5e-22 79.7 4.9 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EAY00011.1 - 2.3e-20 72.1 0.3 3.8e-10 39.5 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EAY00011.1 - 2e-18 65.9 17.0 2.2e-16 59.4 6.1 3.4 3 0 0 3 3 3 2 Variant UBP zinc finger UCH_1 PF13423.6 EAY00011.1 - 2.4e-13 50.4 10.3 5.7e-11 42.6 0.5 3.1 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase HOIP-UBA PF16678.5 EAY00011.1 - 0.0072 16.3 0.1 0.4 10.7 0.0 2.7 2 1 1 3 3 3 1 HOIP UBA domain pair OrsD PF12013.8 EAY00011.1 - 0.015 15.7 2.2 12 6.4 1.8 3.0 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF695 PF05117.12 EAY00011.1 - 0.052 13.7 0.0 4.1 7.6 0.0 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF695) DUF3173 PF11372.8 EAY00011.1 - 0.081 12.8 0.0 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3173) UBA_4 PF14555.6 EAY00011.1 - 0.11 12.4 0.1 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 UBA-like domain RIIa PF02197.17 EAY00012.1 - 2e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MHB PF16525.5 EAY00012.1 - 0.058 13.6 0.1 0.078 13.2 0.1 1.3 1 1 0 1 1 1 0 Haemophore, haem-binding ScsC_N PF18312.1 EAY00012.1 - 0.51 10.2 0.3 0.51 10.2 0.3 2.3 2 1 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain Gly_rich PF12810.7 EAY00013.1 - 5.7e-22 78.8 25.7 7.1e-22 78.5 25.7 1.0 1 0 0 1 1 1 1 Glycine rich protein LXG PF04740.12 EAY00014.1 - 0.0016 18.2 7.5 0.0016 18.2 7.5 2.2 2 1 0 2 2 2 1 LXG domain of WXG superfamily DUF3450 PF11932.8 EAY00014.1 - 0.0041 16.5 12.0 0.0041 16.5 12.0 2.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.5 EAY00014.1 - 0.0043 16.6 14.9 0.12 11.9 8.7 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MscS_porin PF12795.7 EAY00014.1 - 0.011 15.3 10.9 0.016 14.7 10.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 EAY00014.1 - 0.019 15.1 19.1 0.029 14.5 18.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EAY00014.1 - 0.065 13.0 0.3 0.065 13.0 0.3 3.3 2 1 1 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 EAY00014.1 - 0.066 13.5 18.6 0.05 13.8 7.6 3.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4164 PF13747.6 EAY00014.1 - 0.081 13.2 15.6 1.6 9.1 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Fez1 PF06818.15 EAY00014.1 - 0.12 12.8 13.5 0.42 11.0 13.5 1.9 1 1 0 1 1 1 0 Fez1 DUF724 PF05266.14 EAY00014.1 - 0.12 12.2 13.1 0.67 9.8 13.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 EAY00014.1 - 0.13 12.7 0.5 0.13 12.7 0.5 4.2 3 1 3 6 6 6 0 Flagella accessory protein C (FlaC) Rootletin PF15035.6 EAY00014.1 - 0.13 12.2 13.8 0.2 11.7 13.8 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Csm1_N PF18504.1 EAY00014.1 - 0.15 12.4 0.5 0.15 12.4 0.5 2.7 1 1 0 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EAY00014.1 - 0.19 11.3 6.2 0.23 11.0 6.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 EAY00014.1 - 0.21 11.6 10.9 0.8 9.7 0.3 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 EAY00014.1 - 0.36 9.9 13.1 1 8.4 13.1 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EAY00014.1 - 0.36 11.0 16.3 1.8 8.8 13.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 EAY00014.1 - 0.39 10.7 19.3 0.2 11.7 15.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 EAY00014.1 - 0.53 10.9 2.8 0.69 10.6 1.3 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ERM PF00769.19 EAY00014.1 - 0.59 9.9 18.4 0.038 13.8 13.6 1.4 2 0 0 2 2 1 0 Ezrin/radixin/moesin family SID-1_RNA_chan PF13965.6 EAY00014.1 - 0.82 8.0 4.3 0.82 8.0 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DHR10 PF18595.1 EAY00014.1 - 0.86 9.7 16.3 7.7 6.6 8.9 2.8 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF2935 PF11155.8 EAY00014.1 - 1 9.7 5.8 4.9 7.5 4.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4200 PF13863.6 EAY00014.1 - 1.1 9.7 23.0 0.17 12.3 12.7 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) Tweety PF04906.13 EAY00014.1 - 1.1 7.9 6.1 2.8 6.5 5.0 1.9 1 1 1 2 2 2 0 Tweety DUF4407 PF14362.6 EAY00014.1 - 1.6 8.0 9.6 3 7.1 9.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EAY00014.1 - 1.8 7.4 20.2 11 4.8 19.3 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EAY00014.1 - 1.9 9.1 19.3 17 5.9 19.3 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Vfa1 PF08432.10 EAY00014.1 - 1.9 8.8 9.4 3.2 8.1 9.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2203 PF09969.9 EAY00014.1 - 2 9.2 12.0 1.5e+02 3.1 10.9 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med30 PF11315.8 EAY00014.1 - 2.2 8.5 18.9 0.66 10.2 13.0 2.6 2 1 0 2 2 2 0 Mediator complex subunit 30 DUF1664 PF07889.12 EAY00014.1 - 2.6 8.1 14.7 1.5 8.9 6.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 EAY00014.1 - 3.5 8.1 12.2 2.5 8.6 0.6 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 EAY00014.1 - 3.8 7.1 9.9 4.1 6.9 3.5 2.3 1 1 1 2 2 2 0 fzo-like conserved region zf-C4H2 PF10146.9 EAY00014.1 - 4.2 7.6 18.1 3.5 7.9 16.6 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein ATP-synt_E PF05680.12 EAY00014.1 - 8 6.9 11.0 5.3 7.5 8.6 2.1 2 1 0 2 2 1 0 ATP synthase E chain Bromodomain PF00439.25 EAY00015.1 - 2.2e-22 78.9 0.9 5.1e-22 77.7 0.2 1.9 2 0 0 2 2 2 1 Bromodomain Cluap1 PF10234.9 EAY00016.1 - 0.45 9.9 26.3 0.98 8.8 9.6 2.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 Tup_N PF08581.10 EAY00016.1 - 0.6 10.5 16.4 0.39 11.0 4.1 3.1 1 1 1 2 2 2 0 Tup N-terminal TMPIT PF07851.13 EAY00016.1 - 7.3 5.7 25.3 2.2 7.5 7.6 2.3 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 EAY00016.1 - 9.5 5.5 19.2 0.96 8.7 14.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stanniocalcin PF03298.13 EAY00017.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 1 0 0 1 1 1 0 Stanniocalcin family XPC-binding PF09280.11 EAY00018.1 - 0.019 14.7 3.4 0.72 9.6 3.7 2.4 2 1 0 2 2 2 0 XPC-binding domain Raftlin PF15250.6 EAY00019.1 - 0.092 11.5 4.1 0.11 11.3 4.1 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 EAY00019.1 - 3.2 5.9 7.3 3.7 5.7 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Ofd1_CTDD PF10637.9 EAY00019.1 - 8.1 5.7 10.7 24 4.2 10.7 1.8 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF3447 PF11929.8 EAY00020.1 - 1.4e-36 124.3 9.6 1.4e-36 124.3 9.6 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00020.1 - 7.4e-35 119.4 20.4 2.2e-18 66.6 2.5 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00020.1 - 5.9e-26 89.7 5.5 3.2e-07 30.5 0.0 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAY00020.1 - 4.3e-25 87.7 8.5 6.1e-08 33.1 0.1 6.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00020.1 - 2.3e-23 79.7 5.9 1.5e-05 25.0 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAY00020.1 - 3.2e-16 59.2 1.0 2.7e-08 33.9 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) DUF2149 PF09919.9 EAY00020.1 - 0.069 13.4 2.5 6.5 7.1 0.1 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DNA_pol_E_B PF04042.16 EAY00022.1 - 6.7e-19 68.1 0.0 9.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EAY00022.1 - 0.001 19.2 0.0 0.0048 17.0 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Pkinase PF00069.25 EAY00023.1 - 1.8e-38 132.4 0.1 2.4e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00023.1 - 5e-18 65.3 0.0 6.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00023.1 - 3.5e-08 33.1 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cpn60_TCP1 PF00118.24 EAY00024.1 - 1.7e-157 525.0 5.3 2e-157 524.8 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EAY00025.1 - 9.6e-73 242.8 0.0 2.6e-45 154.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAY00025.1 - 9.3e-25 86.2 2.2 3.7e-12 45.8 0.2 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EAY00025.1 - 2.8e-14 53.9 0.8 4.2e-05 24.0 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EAY00025.1 - 3.9e-11 43.4 0.5 0.002 18.4 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 EAY00025.1 - 3.6e-10 40.0 0.0 6.7e-05 22.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 EAY00025.1 - 2e-09 37.8 0.0 9.5e-06 25.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAY00025.1 - 7.6e-09 35.5 0.0 0.00032 20.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EAY00025.1 - 1.1e-08 35.0 0.0 0.00035 20.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 EAY00025.1 - 1.1e-07 32.0 0.2 0.0054 16.6 0.0 3.9 3 1 1 4 4 4 1 Bacterial dnaA protein TIP49 PF06068.13 EAY00025.1 - 1.8e-07 30.7 1.4 0.0025 17.1 0.1 3.0 2 1 0 3 3 3 2 TIP49 P-loop domain AAA_5 PF07728.14 EAY00025.1 - 1.8e-07 31.2 0.0 0.0051 16.8 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EAY00025.1 - 2.7e-07 30.7 0.1 0.034 14.0 0.0 4.1 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAY00025.1 - 3.1e-07 30.7 0.0 0.025 14.9 0.0 2.9 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.12 EAY00025.1 - 3.9e-07 30.2 0.0 0.039 13.9 0.0 3.5 2 1 1 3 3 3 2 NACHT domain AAA_25 PF13481.6 EAY00025.1 - 1.6e-06 27.8 0.0 0.29 10.7 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EAY00025.1 - 1.3e-05 25.4 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAY00025.1 - 1.3e-05 24.7 0.2 0.038 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EAY00025.1 - 2.5e-05 24.8 0.0 0.22 12.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 EAY00025.1 - 3.8e-05 23.4 0.0 0.43 10.3 0.0 3.1 2 2 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EAY00025.1 - 4.1e-05 23.6 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EAY00025.1 - 9.5e-05 22.2 0.0 0.28 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EAY00025.1 - 0.00011 22.7 0.0 0.059 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAY00025.1 - 0.00012 21.4 0.0 0.061 12.5 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 EAY00025.1 - 0.00022 20.7 1.1 7 5.9 0.0 4.3 5 0 0 5 5 5 0 KaiC NB-ARC PF00931.22 EAY00025.1 - 0.00024 20.4 0.0 0.33 10.1 0.0 2.6 2 1 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 EAY00025.1 - 0.00036 20.8 0.0 0.073 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EAY00025.1 - 0.0013 18.2 0.3 0.62 9.5 0.0 3.5 3 1 0 3 3 2 1 Signal recognition particle receptor beta subunit PhoH PF02562.16 EAY00025.1 - 0.0014 18.1 0.1 0.26 10.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 EAY00025.1 - 0.0017 17.9 0.0 0.75 9.3 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EAY00025.1 - 0.0018 18.4 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 EAY00025.1 - 0.0032 17.4 0.2 5.1 7.0 0.1 2.9 2 1 1 3 3 3 0 Rad17 P-loop domain PduV-EutP PF10662.9 EAY00025.1 - 0.0047 16.7 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.15 EAY00025.1 - 0.014 14.2 0.0 1.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein T2SSE PF00437.20 EAY00025.1 - 0.015 14.4 0.0 0.73 8.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MCM PF00493.23 EAY00025.1 - 0.019 14.1 0.0 0.18 10.9 0.0 2.2 2 1 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 EAY00025.1 - 0.021 14.0 0.0 0.48 9.5 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 EAY00025.1 - 0.021 14.1 0.1 1.5 8.0 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin KAP_NTPase PF07693.14 EAY00025.1 - 0.025 13.8 0.1 2.5 7.2 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Parvo_NS1 PF01057.17 EAY00025.1 - 0.027 13.6 0.2 0.19 10.8 0.0 2.2 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EAY00025.1 - 0.041 14.3 1.8 3.4 8.1 0.0 3.6 4 1 0 4 4 2 0 AAA domain AAA_11 PF13086.6 EAY00025.1 - 0.053 13.3 0.0 6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAY00025.1 - 0.076 13.4 0.1 3.6 7.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EAY00025.1 - 0.081 12.6 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 EAY00025.1 - 0.12 12.5 0.0 3.3 7.8 0.0 2.8 3 0 0 3 3 2 0 Torsin AAA_30 PF13604.6 EAY00025.1 - 0.12 12.1 0.3 3.3 7.4 0.0 2.7 3 1 0 3 3 2 0 AAA domain Hydantoinase_B PF02538.14 EAY00025.1 - 0.16 10.4 0.0 0.28 9.5 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF5332 PF17266.2 EAY00025.1 - 0.17 11.5 0.8 0.28 10.8 0.1 1.6 2 0 0 2 2 1 0 Family of unknown function (DUF5332) AAA_23 PF13476.6 EAY00025.1 - 0.2 12.1 2.2 13 6.2 0.1 3.0 3 1 0 3 3 2 0 AAA domain LRR_4 PF12799.7 EAY00026.1 - 2.8e-08 33.9 9.7 3.4e-06 27.3 1.5 4.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY00026.1 - 1.4e-07 31.2 1.3 2e-07 30.7 1.0 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EAY00026.1 - 0.023 14.5 0.6 0.023 14.5 0.6 3.1 3 1 1 4 4 4 0 Leucine rich repeat CM_2 PF01817.21 EAY00026.1 - 0.067 13.5 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Chorismate mutase type II CCDC-167 PF15188.6 EAY00026.1 - 0.22 11.9 3.7 3.2 8.2 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 MULE PF10551.9 EAY00027.1 - 1.9e-10 41.0 1.4 2.4e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAY00027.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Ank_4 PF13637.6 EAY00028.1 - 1.4e-53 178.6 17.3 1e-11 45.1 0.3 9.5 3 1 7 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00028.1 - 4.1e-52 174.7 33.3 5.4e-17 62.2 3.7 6.2 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00028.1 - 6.7e-51 168.6 14.8 2.7e-07 30.7 0.1 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 EAY00028.1 - 6.5e-41 133.6 19.1 4.7e-05 23.5 0.2 10.5 10 1 1 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EAY00028.1 - 6.3e-37 125.2 6.3 4.9e-09 36.3 0.1 6.8 5 1 2 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00028.1 - 2.3e-35 120.4 6.5 2.3e-35 120.4 6.5 4.9 4 2 0 4 4 4 1 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAY00028.1 - 0.00018 21.6 5.8 0.27 11.4 0.0 6.0 5 1 2 7 7 7 1 Protein of unknown function (DUF3718) Ank_4 PF13637.6 EAY00029.1 - 1.1e-19 70.5 0.6 2.6e-08 34.2 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY00029.1 - 9.4e-17 60.6 0.6 2.1e-05 24.8 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAY00029.1 - 1.5e-15 57.5 2.2 9.7e-14 51.7 0.7 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00029.1 - 1.8e-10 40.1 0.2 0.0036 17.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAY00029.1 - 2.2e-09 37.4 0.2 1.2e-07 31.9 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) FHA PF00498.26 EAY00031.1 - 1.4e-06 28.5 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain PCI PF01399.27 EAY00032.1 - 0.0091 16.5 1.3 0.012 16.1 1.3 1.3 1 0 0 1 1 1 1 PCI domain TMF_DNA_bd PF12329.8 EAY00032.1 - 0.015 15.3 12.1 0.021 14.8 3.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EAY00032.1 - 0.051 14.0 14.6 0.2 12.1 0.5 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Imm5 PF14423.6 EAY00032.1 - 0.085 13.1 1.5 0.097 12.9 1.5 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 Occludin_ELL PF07303.13 EAY00032.1 - 0.17 12.6 7.8 0.1 13.4 3.6 1.9 1 1 1 2 2 2 0 Occludin homology domain Com_YlbF PF06133.11 EAY00032.1 - 0.23 12.1 11.2 0.35 11.5 10.4 1.7 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA YabA PF06156.13 EAY00032.1 - 0.26 11.9 6.7 0.94 10.2 6.7 1.8 1 1 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 EAY00032.1 - 0.48 10.8 9.8 0.62 10.4 9.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rho_Binding PF08912.11 EAY00032.1 - 3.6 8.5 11.7 2.9 8.8 1.9 2.1 1 1 1 2 2 2 0 Rho Binding MULE PF10551.9 EAY00033.1 - 2.5e-11 43.8 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5365 PF17326.2 EAY00033.1 - 0.012 16.0 0.7 0.27 11.7 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) FLYWCH PF04500.16 EAY00033.1 - 0.12 12.5 3.6 0.23 11.6 3.6 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF4065 PF13274.6 EAY00033.1 - 0.13 13.2 0.3 2.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Lipase_3 PF01764.25 EAY00034.1 - 2e-13 50.4 0.0 4.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EAY00034.1 - 0.0088 15.6 0.4 0.029 13.9 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) CPP1-like PF11833.8 EAY00034.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SBBP PF06739.11 EAY00034.1 - 0.091 12.8 5.5 0.08 12.9 3.5 1.9 2 0 0 2 2 2 0 Beta-propeller repeat Gly_rich PF12810.7 EAY00035.1 - 1.7e-32 113.3 46.6 2.1e-32 113.0 46.6 1.1 1 0 0 1 1 1 1 Glycine rich protein DENN PF02141.21 EAY00036.1 - 1.4e-25 90.4 4.6 1.4e-25 90.4 4.6 2.4 2 0 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 EAY00036.1 - 0.00029 19.7 3.7 0.0013 17.5 1.6 2.1 1 1 1 2 2 2 1 Transport protein Avl9 SPA PF08616.10 EAY00036.1 - 0.024 14.6 0.4 0.066 13.2 0.4 1.8 1 0 0 1 1 1 0 Stabilization of polarity axis DUF4108 PF13390.6 EAY00037.1 - 3.3e-58 195.7 7.9 3.6e-58 195.5 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF5065 PF16723.5 EAY00039.1 - 0.021 14.9 3.3 0.51 10.4 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5065) Ank_2 PF12796.7 EAY00040.1 - 5.8e-26 90.9 0.2 6.9e-15 55.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00040.1 - 2.8e-18 66.0 4.4 1.4e-05 25.5 0.0 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00040.1 - 8.6e-17 61.0 0.7 1.1e-12 47.8 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Pkinase PF00069.25 EAY00040.1 - 2.1e-16 60.1 0.0 6.7e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 EAY00040.1 - 4e-13 48.3 3.0 0.0017 18.6 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EAY00040.1 - 5.7e-13 48.7 0.2 0.0003 21.1 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Pkinase_Tyr PF07714.17 EAY00040.1 - 1.9e-11 43.8 0.4 3.5e-10 39.6 0.4 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase CLZ PF16526.5 EAY00041.1 - 0.36 11.2 10.8 18 5.8 0.4 5.1 3 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YjcZ PF13990.6 EAY00041.1 - 0.88 8.9 9.3 0.37 10.1 2.3 2.7 1 1 2 3 3 3 0 YjcZ-like protein CRIC_ras_sig PF10534.9 EAY00041.1 - 1.3 9.3 6.0 5.1 7.3 0.1 3.7 3 0 0 3 3 3 0 Connector enhancer of kinase suppressor of ras Spike_torovirin PF17072.5 EAY00041.1 - 1.8 5.6 9.9 2.3 5.3 9.9 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Trypan_glycop PF00913.19 EAY00041.1 - 3.5 6.8 9.4 0.051 12.8 1.9 1.6 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Fzo_mitofusin PF04799.13 EAY00041.1 - 5.2 6.6 23.7 1.1 8.8 0.3 4.6 1 1 4 5 5 5 0 fzo-like conserved region AIP3 PF03915.13 EAY00041.1 - 7.7 5.5 34.1 0.1 11.7 20.2 2.5 1 1 1 2 2 2 0 Actin interacting protein 3 DASH_Dam1 PF08653.10 EAY00041.1 - 9.1 6.2 8.9 2.7 7.8 0.2 4.2 3 1 1 4 4 4 0 DASH complex subunit Dam1 Apt1 PF10351.9 EAY00042.1 - 0.00013 21.0 4.3 0.0098 14.8 0.6 3.2 3 0 0 3 3 3 2 Golgi-body localisation protein domain Pkinase PF00069.25 EAY00043.1 - 3.9e-31 108.4 0.0 4.6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00043.1 - 2.2e-17 63.2 0.0 2.8e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY00043.1 - 0.00018 20.6 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAY00043.1 - 0.0037 17.2 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAY00043.1 - 0.0044 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAY00043.1 - 0.0059 16.0 0.3 0.011 15.1 0.1 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP-FF1 PF16512.5 EAY00043.1 - 0.086 13.5 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Ank_2 PF12796.7 EAY00044.1 - 5.4e-25 87.8 3.5 2.4e-13 50.5 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00044.1 - 4e-20 71.9 5.4 2.9e-08 34.1 0.2 4.9 2 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00044.1 - 2.2e-13 50.2 0.2 0.0022 18.3 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00044.1 - 3.2e-13 48.6 0.5 0.61 10.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EAY00044.1 - 7.5e-11 41.8 2.8 7.5e-11 41.8 2.8 4.4 4 1 1 6 6 6 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAY00044.1 - 3.7e-10 39.8 0.1 0.91 10.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAY00045.1 - 4.4e-13 49.5 0.4 4.7e-10 39.8 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00045.1 - 4.9e-11 43.1 0.5 8.9e-11 42.2 0.5 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00045.1 - 4.8e-09 35.7 0.0 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAY00045.1 - 4.7e-08 33.1 0.1 1.4e-05 25.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY00045.1 - 4.4e-07 30.1 0.0 6.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Stap_Strp_toxin PF01123.20 EAY00045.1 - 0.056 14.3 0.1 0.067 14.0 0.1 1.1 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain PPR_long PF17177.4 EAY00045.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP z-alpha PF02295.17 EAY00045.1 - 0.14 12.2 0.2 0.2 11.7 0.2 1.3 1 1 0 1 1 1 0 Adenosine deaminase z-alpha domain DHR-2 PF06920.13 EAY00046.1 - 5.3e-57 193.6 4.8 4.9e-53 180.6 2.1 2.3 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 EAY00046.1 - 2e-10 40.8 1.1 6.2e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins KilA-N PF04383.13 EAY00047.1 - 1.6e-14 53.7 0.1 3.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 KilA-N domain Tox-GHH PF15636.6 EAY00047.1 - 0.044 13.8 0.5 0.45 10.5 0.0 2.5 2 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4795 PF16043.5 EAY00048.1 - 0.062 12.9 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1947 PF09183.10 EAY00048.1 - 0.18 12.1 7.5 2.3 8.6 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) CAP_N PF01213.19 EAY00049.1 - 0.15 11.5 0.1 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RGCC PF15151.6 EAY00049.1 - 0.19 11.9 0.8 0.31 11.3 0.2 1.7 2 0 0 2 2 2 0 Response gene to complement 32 protein family Spectrin_like PF18373.1 EAY00050.1 - 0.011 15.8 1.9 0.018 15.1 1.8 1.5 1 1 0 1 1 1 0 Spectrin like domain Popeye PF04831.13 EAY00050.1 - 0.066 13.4 0.2 0.075 13.2 0.2 1.2 1 0 0 1 1 1 0 Popeye protein conserved region Trypan_PARP PF05887.11 EAY00051.1 - 0.094 12.7 6.9 0.15 12.1 6.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY00052.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY00052.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Gly-zipper_Omp PF13488.6 EAY00054.1 - 0.0087 16.0 7.7 0.015 15.3 7.7 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAY00054.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAY00054.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAY00054.1 - 0.33 11.3 4.2 0.51 10.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Tho2 PF11262.8 EAY00055.1 - 0.13 11.5 3.6 0.13 11.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TPR_2 PF07719.17 EAY00056.1 - 3.8e-28 95.3 11.3 2.4e-05 24.1 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAY00056.1 - 9.6e-24 82.1 6.3 0.0025 18.5 0.0 10.2 4 3 7 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EAY00056.1 - 2.1e-22 77.4 8.4 0.0011 19.0 0.0 9.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAY00056.1 - 5.2e-22 76.7 10.2 0.0012 18.6 0.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAY00056.1 - 3.3e-19 69.2 8.8 3.6e-05 24.2 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAY00056.1 - 1.6e-17 63.8 1.4 3.3e-06 27.6 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAY00056.1 - 3.9e-17 61.3 1.0 0.0036 17.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAY00056.1 - 7.4e-17 61.4 12.5 1e-05 25.6 3.3 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAY00056.1 - 3.6e-13 49.6 16.1 0.032 14.5 0.0 7.3 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EAY00056.1 - 1.4e-10 41.2 0.1 0.075 13.2 0.0 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAY00056.1 - 3.3e-10 39.5 0.1 0.055 13.2 0.0 6.7 8 0 0 8 8 8 2 TPR repeat TPR_7 PF13176.6 EAY00056.1 - 1.1e-06 28.2 1.2 2.6 8.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAY00056.1 - 1.4e-06 27.9 5.2 3.4 7.6 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 EAY00056.1 - 2.6e-06 26.6 7.7 0.45 9.4 0.0 4.9 1 1 4 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EAY00056.1 - 1.2e-05 24.7 4.3 0.17 11.1 0.9 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAY00056.1 - 0.00041 20.0 0.0 2.7 7.6 0.0 4.1 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EAY00056.1 - 0.00043 20.7 12.0 1 10.1 0.0 7.4 10 0 0 10 10 7 1 Tetratricopeptide repeat HemY_N PF07219.13 EAY00056.1 - 0.0055 16.9 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 1 HemY protein N-terminus TPR_4 PF07721.14 EAY00056.1 - 0.018 15.6 0.0 55 4.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat COPI_C PF06957.11 EAY00056.1 - 0.037 12.8 0.2 4.7 5.9 0.0 2.8 3 0 0 3 3 3 0 Coatomer (COPI) alpha subunit C-terminus MIT PF04212.18 EAY00056.1 - 0.054 13.6 1.8 9.6 6.4 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Glyco_hydro_65m PF03632.15 EAY00056.1 - 0.068 12.0 0.1 0.37 9.6 0.0 2.1 2 1 0 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain OTCace_N PF02729.21 EAY00056.1 - 0.11 12.6 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF627 PF04781.12 EAY00056.1 - 1.4 9.0 6.8 13 5.8 0.0 4.4 4 2 1 5 5 5 0 Protein of unknown function (DUF627) Jnk-SapK_ap_N PF09744.9 EAY00057.1 - 0.0073 16.5 21.3 0.0073 16.5 21.3 10.0 2 2 5 8 8 8 2 JNK_SAPK-associated protein-1 PKcGMP_CC PF16808.5 EAY00057.1 - 0.015 15.1 18.4 0.063 13.1 1.3 6.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 7TM-7TMR_HD PF07698.11 EAY00058.1 - 0.034 13.9 9.2 0.048 13.4 9.2 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF2198 PF09964.9 EAY00058.1 - 1.1 9.4 7.5 3.7 7.7 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Guanylate_cyc PF00211.20 EAY00059.1 - 0.00034 20.3 0.0 0.00035 20.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Thioredoxin PF00085.20 EAY00060.1 - 0.0011 19.0 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin ARTD15_N PF18084.1 EAY00061.1 - 0.069 13.4 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 ARTD15 N-terminal domain DCP2 PF05026.13 EAY00061.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 Dcp2, box A domain Mito_carr PF00153.27 EAY00062.1 - 2.9e-28 97.6 0.2 3.6e-11 42.8 0.1 3.3 1 1 2 3 3 3 3 Mitochondrial carrier protein Ldh_1_N PF00056.23 EAY00063.1 - 1.4e-24 86.8 0.0 1.8e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAY00063.1 - 1e-06 28.8 0.0 3.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DbpA PF03880.15 EAY00063.1 - 0.14 12.2 0.0 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Ldh_1_C PF02866.18 EAY00064.1 - 3e-13 50.0 0.0 3.3e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Carbam_trans_C PF16861.5 EAY00065.1 - 0.19 11.3 0.4 2.1 7.9 0.2 2.0 1 1 1 2 2 2 0 Carbamoyltransferase C-terminus Gly_rich PF12810.7 EAY00066.1 - 1.1e-17 64.8 27.7 1.3e-17 64.6 27.7 1.0 1 0 0 1 1 1 1 Glycine rich protein Tubulin PF00091.25 EAY00067.1 - 5.9e-68 229.0 0.0 8.4e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAY00067.1 - 2.4e-50 169.9 0.0 3.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAY00067.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAY00067.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SCAMP PF04144.13 EAY00069.1 - 0.0062 16.9 13.5 0.013 15.8 13.5 1.5 1 1 0 1 1 1 1 SCAMP family DUF3382 PF11862.8 EAY00069.1 - 0.018 15.3 2.5 0.034 14.4 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) Tetraspanin PF00335.20 EAY00069.1 - 0.027 14.2 18.8 0.13 11.9 13.1 2.1 1 1 1 2 2 2 0 Tetraspanin family TssO PF17561.2 EAY00069.1 - 0.035 14.2 0.0 0.035 14.2 0.0 2.6 3 0 0 3 3 3 0 Type VI secretion system, TssO DHHC PF01529.20 EAY00069.1 - 0.037 14.1 14.7 0.14 12.2 2.9 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Orf78 PF06024.12 EAY00069.1 - 0.24 11.7 0.0 0.24 11.7 0.0 3.3 1 1 2 3 3 2 0 Orf78 (ac78) CcmE PF03100.15 EAY00069.1 - 0.33 10.9 3.6 0.63 10.0 0.0 2.6 1 1 1 3 3 3 0 CcmE DUF996 PF06195.13 EAY00069.1 - 1.3 9.3 16.3 0.56 10.5 11.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF996) DUF2207 PF09972.9 EAY00069.1 - 1.7 7.3 13.8 0.41 9.3 0.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3333 PF11812.8 EAY00069.1 - 4.7 7.4 7.9 10 6.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) EphA2_TM PF14575.6 EAY00069.1 - 7.1 7.6 8.9 20 6.2 0.1 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Gly_rich PF12810.7 EAY00070.1 - 7.3e-39 134.1 19.0 9.1e-39 133.8 19.0 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3447 PF11929.8 EAY00071.1 - 1.6e-37 127.3 6.8 1.6e-37 127.3 6.8 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00071.1 - 0.0076 16.8 0.2 0.56 10.8 0.1 2.8 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00071.1 - 0.048 14.2 0.2 83 3.9 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00071.1 - 0.16 12.7 0.7 11 7.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Cnd1 PF12717.7 EAY00073.1 - 0.0057 16.7 0.6 0.0057 16.7 0.6 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 PIN_6 PF17146.4 EAY00073.1 - 0.01 16.3 0.2 0.15 12.6 0.0 2.9 3 1 0 3 3 3 0 PIN domain of ribonuclease MORN PF02493.20 EAY00074.1 - 6.2e-25 85.6 25.4 8.1e-09 34.9 0.7 7.0 7 0 0 7 7 7 6 MORN repeat TLD PF07534.16 EAY00075.1 - 4.1e-27 95.1 0.1 4.3e-26 91.8 0.1 2.3 2 0 0 2 2 2 1 TLD zf-B_box PF00643.24 EAY00075.1 - 1.7e-12 47.3 24.3 8.6e-07 29.0 5.4 2.3 2 0 0 2 2 2 2 B-box zinc finger GlutR_N PF05201.15 EAY00075.1 - 0.0014 18.4 0.9 0.0029 17.4 0.5 1.8 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain PARP PF00644.20 EAY00075.1 - 0.0049 16.5 0.1 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain RdRP_3 PF00998.23 EAY00075.1 - 0.059 12.1 1.1 0.11 11.2 1.1 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase CEP209_CC5 PF16574.5 EAY00075.1 - 0.14 12.3 4.4 0.3 11.2 4.4 1.5 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DUF1664 PF07889.12 EAY00075.1 - 0.18 11.9 3.0 0.38 10.8 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EAY00075.1 - 1.2 9.2 8.5 0.69 10.0 0.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 EAY00075.1 - 4.6 7.7 9.2 16 5.9 9.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2897 PF11446.8 EAY00076.1 - 0.33 10.9 3.2 0.61 10.0 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAY00077.1 - 1e-64 216.8 6.2 1.1e-64 216.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAY00077.1 - 0.11 12.7 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Fumble PF03630.14 EAY00078.1 - 1.6e-49 168.9 0.6 2.6e-48 164.9 0.6 2.2 1 1 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 EAY00078.1 - 0.004 16.7 0.1 0.021 14.3 0.1 2.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Pan_kinase PF03309.14 EAY00078.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Type III pantothenate kinase Taeniidae_ag PF05596.11 EAY00078.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Taeniidae antigen RNA_pol_A_bac PF01000.26 EAY00079.1 - 9.4e-24 83.9 0.0 2.9e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAY00079.1 - 1.9e-16 59.3 0.0 2.8e-16 58.7 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1272 PF06906.11 EAY00079.1 - 2.7 8.2 8.3 0.96 9.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF4108 PF13390.6 EAY00081.1 - 6e-58 194.8 5.2 6.7e-58 194.7 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAY00081.1 - 0.095 13.0 0.0 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Peptidase_C13 PF01650.18 EAY00083.1 - 1.5e-64 217.9 0.3 2.2e-64 217.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family LRR_5 PF13306.6 EAY00084.1 - 2.1e-82 273.4 61.0 3.4e-22 78.8 7.4 5.4 2 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00084.1 - 1e-14 54.0 8.6 0.00062 19.5 0.0 8.0 6 3 2 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EAY00084.1 - 3.9e-05 23.9 15.7 0.15 12.6 0.1 6.9 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) GED PF02212.18 EAY00085.1 - 0.0088 16.2 5.9 0.81 9.9 0.0 2.9 2 0 0 2 2 2 2 Dynamin GTPase effector domain GAT PF03127.14 EAY00085.1 - 0.58 10.5 9.6 1.5 9.2 0.4 3.5 3 0 0 3 3 3 0 GAT domain Xpo1 PF08389.12 EAY00086.1 - 1.4e-11 44.7 1.4 1.4e-11 44.7 1.4 4.2 5 1 0 5 5 5 1 Exportin 1-like protein MSP7_C PF12948.7 EAY00086.1 - 0.042 14.5 0.3 0.042 14.5 0.3 4.1 5 0 0 5 5 5 0 MSP7-like protein C-terminal domain IBN_N PF03810.19 EAY00086.1 - 0.3 11.0 1.8 1.5 8.8 0.0 3.2 4 0 0 4 4 4 0 Importin-beta N-terminal domain BAR PF03114.18 EAY00086.1 - 0.42 10.2 8.7 0.037 13.7 0.9 2.9 2 1 0 2 2 2 0 BAR domain zf-HIT PF04438.16 EAY00087.1 - 8.1e-06 25.6 15.9 1.1e-05 25.2 15.9 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 EAY00087.1 - 0.099 12.8 14.1 0.14 12.3 14.1 1.2 1 0 0 1 1 1 0 B-box zinc finger STI1 PF17830.1 EAY00087.1 - 0.13 12.2 1.2 0.71 9.9 0.0 2.6 4 0 0 4 4 4 0 STI1 domain DUF3322 PF11795.8 EAY00087.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) PolC_DP2 PF03833.13 EAY00087.1 - 4.6 5.0 5.2 4.6 5.0 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 EAY00087.1 - 9.5 6.4 15.7 21 5.3 15.7 1.5 1 1 0 1 1 1 0 MYND finger CLP1_P PF16575.5 EAY00088.1 - 9.4e-35 120.1 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ParA PF10609.9 EAY00088.1 - 0.0072 15.8 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ABC_tran PF00005.27 EAY00088.1 - 0.014 16.0 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EAY00088.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EAY00088.1 - 0.07 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EAY00088.1 - 0.082 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAY00088.1 - 0.089 13.3 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAY00088.1 - 0.19 11.2 0.4 0.28 10.6 0.4 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 EAY00088.1 - 0.21 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EAY00088.1 - 0.23 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Vps16_N PF04841.13 EAY00089.1 - 1e-10 41.0 0.0 1.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Clathrin PF00637.20 EAY00089.1 - 0.0024 17.8 2.7 0.0055 16.6 2.7 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS TRIC PF05197.13 EAY00090.1 - 0.0081 15.8 5.1 0.021 14.4 3.7 2.2 1 1 1 2 2 2 1 TRIC channel DPM3 PF08285.11 EAY00090.1 - 1.7 8.9 10.2 0.12 12.6 1.5 3.0 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ubiquitin PF00240.23 EAY00092.1 - 0.004 16.9 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family NAGidase PF07555.13 EAY00092.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Focal_AT PF03623.13 EAY00094.1 - 0.0088 16.0 1.2 0.019 14.9 0.4 2.0 2 0 0 2 2 2 1 Focal adhesion targeting region DUF3381 PF11861.8 EAY00094.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) DUF5344 PF17279.2 EAY00094.1 - 9.6 6.9 8.2 0.52 10.9 0.5 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) tRNA_bind PF01588.20 EAY00095.1 - 1.9e-29 101.6 0.0 4.5e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EAY00095.1 - 6.2e-05 23.1 2.2 9.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAY00095.1 - 0.092 12.9 0.0 0.092 12.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 EAY00095.1 - 0.67 10.4 5.9 2.1 8.7 5.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ank_2 PF12796.7 EAY00096.1 - 4.9e-23 81.5 3.4 1.2e-07 32.2 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00096.1 - 7.7e-16 58.0 3.0 0.00028 21.1 0.0 5.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00096.1 - 8.2e-13 48.6 4.2 0.036 14.6 0.0 5.9 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00096.1 - 5.6e-08 32.4 9.0 0.26 11.9 0.1 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 EAY00096.1 - 0.00065 20.0 3.8 12 6.6 0.0 6.2 7 1 0 7 7 7 1 Ankyrin repeat zf-RING_2 PF13639.6 EAY00097.1 - 6.1e-10 39.3 10.9 1.6e-09 37.9 10.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAY00097.1 - 3.8e-06 27.1 8.2 1.3e-05 25.4 8.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAY00097.1 - 1.9e-05 24.4 9.9 4.6e-05 23.2 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NTP_transferase PF00483.23 EAY00097.1 - 2.4e-05 24.1 0.1 4.3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 EAY00097.1 - 8.3e-05 21.7 2.0 0.00014 20.9 2.0 1.3 1 0 0 1 1 1 1 L-fucokinase zf-C3HC4_3 PF13920.6 EAY00097.1 - 0.00015 21.6 8.3 0.00035 20.4 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAY00097.1 - 0.014 15.2 10.3 0.043 13.7 10.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Hexapep PF00132.24 EAY00097.1 - 0.037 13.8 4.8 0.22 11.3 4.6 2.4 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) zf-RING_5 PF14634.6 EAY00097.1 - 0.038 14.0 10.3 0.1 12.6 10.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain NTP_transf_3 PF12804.7 EAY00097.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain zf-RING_11 PF17123.5 EAY00097.1 - 0.071 12.9 9.7 0.2 11.4 9.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EAY00097.1 - 0.082 13.0 3.3 0.23 11.5 3.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EAY00097.1 - 0.084 12.5 6.6 0.18 11.4 6.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EAY00097.1 - 0.31 11.2 8.4 0.86 9.8 8.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAY00097.1 - 0.45 10.3 7.2 1.3 8.9 7.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EAY00097.1 - 0.76 9.9 9.0 2.2 8.4 9.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 EAY00097.1 - 2.6 8.2 6.5 7.5 6.7 6.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DHR-2 PF06920.13 EAY00098.1 - 1.2e-74 251.9 9.2 1.2e-74 251.9 9.2 1.6 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 EAY00098.1 - 8.4e-06 25.7 0.1 8.4e-06 25.7 0.1 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Peptidase_C1 PF00112.23 EAY00100.1 - 4.6e-17 62.8 7.9 4.5e-12 46.5 1.3 2.0 1 1 1 2 2 2 2 Papain family cysteine protease PBECR2 PF18810.1 EAY00101.1 - 0.11 12.8 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 DUF4107 PF13389.6 EAY00102.1 - 8.9e-73 243.8 3.8 1.2e-72 243.4 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF4107 PF13389.6 EAY00106.1 - 2.1e-71 239.3 3.4 2.8e-71 238.9 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAY00107.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAY00108.1 - 1.2e-155 516.0 13.3 1.5e-155 515.7 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00108.1 - 3.8 8.0 7.9 1.9 9.0 0.7 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAY00110.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAY00111.1 - 0.017 15.5 0.5 0.022 15.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAY00111.1 - 1.4 7.9 2.8 1.5 7.7 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAY00111.1 - 2.7 8.0 5.7 2.9 7.9 5.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAY00112.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAY00113.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY00113.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY00114.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY00114.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Pkinase PF00069.25 EAY00115.1 - 1.5e-65 221.2 0.0 2.6e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00115.1 - 2.5e-32 112.2 0.0 5.8e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00115.1 - 4.8e-08 32.7 0.0 6.3e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAY00115.1 - 7.5e-05 21.7 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAY00115.1 - 0.00048 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Utp12 PF04003.12 EAY00115.1 - 0.0091 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family APH PF01636.23 EAY00115.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAY00115.1 - 0.079 12.6 0.1 7.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf_C2HC_14 PF18574.1 EAY00115.1 - 0.13 12.1 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain Kdo PF06293.14 EAY00115.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf_UBZ PF18439.1 EAY00115.1 - 0.23 11.1 0.9 0.69 9.6 0.9 1.9 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Gly-zipper_Omp PF13488.6 EAY00117.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAY00117.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY00117.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif UVR PF02151.19 EAY00118.1 - 8e-07 28.6 1.7 2.1e-06 27.3 1.7 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif XRCC1_N PF01834.16 EAY00118.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain DUF563 PF04577.14 EAY00119.1 - 0.00073 19.7 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RasGEF PF00617.19 EAY00120.1 - 1.7e-31 109.8 0.2 4.1e-31 108.5 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAY00120.1 - 4.1e-05 23.8 6.3 5.5e-05 23.4 4.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif CAMSAP_CKK PF08683.11 EAY00121.1 - 7.2e-09 35.8 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 EAY00121.1 - 0.0017 18.2 0.0 0.0094 15.8 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain GEP5 PF17053.5 EAY00121.1 - 0.026 14.4 0.5 0.062 13.1 0.4 1.7 1 1 0 1 1 1 0 Genetic interactor of prohibitin 5 ParB PF08775.10 EAY00121.1 - 0.13 12.8 4.6 0.057 13.9 1.5 2.0 2 0 0 2 2 2 0 ParB family DUF4407 PF14362.6 EAY00122.1 - 0.068 12.5 4.1 0.091 12.1 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_III_AB PF09548.10 EAY00122.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4472 PF14739.6 EAY00122.1 - 0.3 11.8 9.7 0.35 11.6 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF641 PF04859.12 EAY00122.1 - 0.42 10.9 6.9 2.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3552 PF12072.8 EAY00122.1 - 0.79 9.1 8.5 6.3 6.2 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF5320 PF17253.2 EAY00122.1 - 1 10.4 2.8 4.8 8.3 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) UN_NPL4 PF11543.8 EAY00123.1 - 0.0059 17.1 1.5 0.011 16.2 0.3 2.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Gly-zipper_Omp PF13488.6 EAY00124.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAY00124.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY00124.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3839 PF12943.7 EAY00127.1 - 2.4e-152 505.3 14.5 3.1e-152 504.9 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAY00127.1 - 0.28 11.8 4.6 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAY00127.1 - 2.2 8.8 7.1 2.1 8.9 0.8 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAF PF01590.26 EAY00128.1 - 0.041 14.5 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 GAF domain TMEM154 PF15102.6 EAY00129.1 - 0.0035 17.3 0.6 0.0071 16.2 0.6 1.4 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 EAY00129.1 - 0.014 15.4 0.5 0.024 14.6 0.5 1.3 1 0 0 1 1 1 0 Protocadherin Shisa PF13908.6 EAY00129.1 - 0.021 15.0 1.3 0.037 14.3 1.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EAY00129.1 - 0.11 13.3 2.9 0.25 12.2 2.9 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAY00129.1 - 0.31 11.1 5.4 1 9.5 5.4 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Flavodoxin_2 PF02525.17 EAY00130.1 - 1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_2 PF02525.17 EAY00131.1 - 0.028 14.1 0.0 0.032 14.0 0.0 1.0 1 0 0 1 1 1 0 Flavodoxin-like fold GDPD PF03009.17 EAY00133.1 - 3e-39 135.3 0.0 4.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EAY00133.1 - 0.023 14.3 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain MGDG_synth PF06925.11 EAY00133.1 - 0.087 12.9 0.2 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase GDPD_2 PF13653.6 EAY00133.1 - 0.15 12.5 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family hDGE_amylase PF14701.6 EAY00134.1 - 1.4e-134 449.5 0.0 2.1e-134 448.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EAY00134.1 - 1.6e-104 349.9 0.1 2.4e-104 349.3 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EAY00134.1 - 1.8e-45 155.6 0.0 2.8e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme bZIP_1 PF00170.21 EAY00136.1 - 0.04 14.0 1.7 0.04 14.0 1.7 3.4 2 2 2 5 5 5 0 bZIP transcription factor DUF948 PF06103.11 EAY00136.1 - 0.096 12.9 6.3 0.98 9.7 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 EAY00136.1 - 0.28 11.7 13.6 0.24 11.9 2.5 3.4 3 1 0 3 3 3 0 Spectrin repeat ALIX_LYPXL_bnd PF13949.6 EAY00136.1 - 0.46 9.7 17.7 0.028 13.7 10.4 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Seryl_tRNA_N PF02403.22 EAY00136.1 - 0.85 9.9 18.6 0.22 11.8 5.1 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 EAY00136.1 - 0.98 8.2 10.7 22 3.8 10.7 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 EAY00136.1 - 1.1 9.4 16.2 0.11 12.6 9.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FTCD_C PF04961.12 EAY00136.1 - 1.9 8.2 7.0 7.1 6.4 2.9 2.7 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Cep57_MT_bd PF06657.13 EAY00136.1 - 2.2 8.8 11.8 0.75 10.3 3.6 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 EAY00136.1 - 3.7 8.0 18.0 1.2 9.6 4.4 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Fmp27_WPPW PF10359.9 EAY00136.1 - 5.9 5.6 14.4 0.19 10.6 6.9 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain YabA PF06156.13 EAY00136.1 - 6.1 7.5 16.0 0.92 10.2 2.5 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Laminin_II PF06009.12 EAY00136.1 - 6.4 6.8 15.9 0.48 10.5 3.0 3.1 1 1 2 3 3 3 0 Laminin Domain II Oxysterol_BP PF01237.18 EAY00138.1 - 3.9e-68 230.0 3.2 1.3e-62 211.8 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3447 PF11929.8 EAY00139.1 - 4.1e-36 122.8 8.7 4.1e-36 122.8 8.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00139.1 - 7.5e-06 26.4 0.4 0.00083 19.9 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00139.1 - 0.0028 18.2 0.1 3.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00139.1 - 0.07 13.7 0.4 28 5.7 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeat RL PF17797.1 EAY00139.1 - 0.2 11.7 0.8 16 5.5 0.1 2.3 2 0 0 2 2 2 0 RL domain DUF1128 PF06569.11 EAY00140.1 - 0.012 15.6 2.0 0.19 11.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) AAA_12 PF13087.6 EAY00142.1 - 6.8e-55 185.8 0.0 1.5e-54 184.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAY00142.1 - 6.1e-31 108.2 0.0 4.9e-19 69.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 EAY00142.1 - 9.6e-23 80.8 4.3 2e-22 79.8 4.3 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 EAY00142.1 - 3e-10 40.2 0.0 2.9e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAY00142.1 - 3.9e-06 26.8 0.1 0.74 9.5 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EAY00142.1 - 8.8e-06 26.1 0.1 0.00014 22.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAY00142.1 - 0.0074 16.6 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAY00142.1 - 0.0076 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAY00142.1 - 0.02 15.3 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF853 PF05872.12 EAY00142.1 - 0.083 11.5 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PhoH PF02562.16 EAY00142.1 - 0.085 12.3 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ADK PF00406.22 EAY00142.1 - 0.16 12.1 0.0 0.51 10.4 0.0 1.8 1 1 0 1 1 1 0 Adenylate kinase DUF3447 PF11929.8 EAY00143.1 - 7.6e-34 115.5 8.7 7.6e-34 115.5 8.7 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00143.1 - 3.8e-22 78.4 1.1 2.5e-10 40.7 0.2 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00143.1 - 2.8e-19 69.5 6.7 4.7e-11 43.1 0.4 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00143.1 - 2.5e-17 62.5 0.1 2.9e-06 27.5 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAY00143.1 - 1.4e-15 57.2 0.4 6.2e-09 36.0 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00143.1 - 1.8e-14 52.4 1.5 0.00039 20.7 0.0 6.4 7 1 1 8 8 8 2 Ankyrin repeat Ycf54 PF10674.9 EAY00143.1 - 0.087 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Spc7 PF08317.11 EAY00144.1 - 0.077 11.9 93.8 0.028 13.3 24.8 4.7 1 1 3 5 5 5 0 Spc7 kinetochore protein DUF4618 PF15397.6 EAY00144.1 - 0.14 11.6 77.4 0.28 10.5 27.8 4.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4618) Filament PF00038.21 EAY00144.1 - 0.4 10.2 78.4 0.046 13.3 14.7 5.5 1 1 4 5 5 5 0 Intermediate filament protein AAA_13 PF13166.6 EAY00144.1 - 0.46 9.1 74.4 0.015 14.0 24.5 3.6 1 1 3 4 4 4 0 AAA domain ATG16 PF08614.11 EAY00144.1 - 0.47 10.7 85.0 1.4 9.1 27.0 4.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.6 EAY00144.1 - 1.5 8.1 96.2 0.086 12.2 10.8 5.5 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EAY00144.1 - 1.6 6.2 79.3 0.18 9.3 42.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EAY00144.1 - 1.7 8.1 84.7 0.54 9.7 24.8 4.0 1 1 3 4 4 4 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EAY00144.1 - 7.9 6.6 93.7 0.22 11.6 9.0 6.3 1 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein Cnd1 PF12717.7 EAY00145.1 - 3e-21 76.1 11.1 8.5e-17 61.7 0.5 4.8 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EAY00145.1 - 4.1e-09 36.6 12.0 9.8e-06 25.8 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EAY00145.1 - 1.2e-08 34.5 9.5 0.54 10.7 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EAY00145.1 - 1.8e-07 31.4 1.4 0.098 13.1 0.0 4.1 2 1 0 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 EAY00145.1 - 1.1e-05 25.5 3.6 3 8.1 0.1 6.0 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EAY00145.1 - 1.9e-05 23.5 16.4 0.0014 17.3 3.8 3.2 2 2 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 EAY00145.1 - 2.4e-05 24.0 10.2 0.012 15.2 0.6 5.0 3 2 2 5 5 5 3 CLASP N terminal HEAT_EZ PF13513.6 EAY00145.1 - 0.06 13.9 1.4 88 3.8 0.1 5.3 5 1 0 6 6 6 0 HEAT-like repeat Arm PF00514.23 EAY00145.1 - 0.17 12.0 0.1 2.4 8.3 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ANAPC4_WD40 PF12894.7 EAY00146.1 - 0.00011 22.4 0.4 0.32 11.3 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5128 PF17170.4 EAY00146.1 - 0.019 14.1 2.1 0.28 10.3 0.1 3.0 3 0 0 3 3 3 0 6-bladed beta-propeller Cyclin_N PF00134.23 EAY00147.1 - 6.6e-24 84.1 1.0 6.6e-24 84.1 1.0 2.2 3 0 0 3 3 3 1 Cyclin, N-terminal domain DUF2630 PF10944.8 EAY00148.1 - 0.76 10.3 5.8 57 4.3 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2630) NEMO PF11577.8 EAY00148.1 - 3.4 7.8 9.0 0.37 10.8 0.3 2.8 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO Ank_2 PF12796.7 EAY00149.1 - 1.1e-40 138.1 22.3 1.4e-16 60.8 2.7 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY00149.1 - 2.6e-39 133.1 8.4 2.6e-39 133.1 8.4 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00149.1 - 9.8e-33 112.1 7.0 2.9e-11 43.7 0.2 6.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00149.1 - 1.5e-31 104.9 6.0 1e-05 25.5 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAY00149.1 - 1.8e-31 107.1 3.4 1.8e-06 28.1 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAY00149.1 - 1e-22 79.8 4.5 3.2e-08 33.7 0.2 5.9 2 2 4 7 7 7 4 Ankyrin repeats (many copies) DUF3718 PF12514.8 EAY00149.1 - 0.00054 20.1 4.0 0.72 10.0 0.1 4.7 3 1 2 5 5 5 1 Protein of unknown function (DUF3718) Chlam_PMP PF02415.17 EAY00150.1 - 0.14 12.7 0.3 0.14 12.7 0.3 8.0 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Phage_Treg PF04761.12 EAY00150.1 - 0.4 10.8 2.6 0.5 10.5 0.0 2.4 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator TssO PF17561.2 EAY00151.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Type VI secretion system, TssO Ion_trans PF00520.31 EAY00151.1 - 0.0097 15.2 0.5 0.066 12.4 0.0 1.9 1 1 1 2 2 2 1 Ion transport protein PA14 PF07691.12 EAY00152.1 - 1.1e-05 25.3 0.2 3e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EAY00152.1 - 3.7e-05 24.0 0.4 7.4e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 GLEYA domain Caldesmon PF02029.15 EAY00152.1 - 0.0009 18.1 48.5 0.0014 17.5 48.5 1.3 1 0 0 1 1 1 1 Caldesmon GREB1 PF15782.5 EAY00152.1 - 0.2 8.7 16.7 0.27 8.3 16.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EVI2A PF05399.11 EAY00152.1 - 0.23 11.0 5.7 0.26 10.9 4.6 1.6 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF572 PF04502.13 EAY00152.1 - 0.48 10.0 32.0 0.82 9.2 32.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) MMR1 PF08505.10 EAY00152.1 - 1.3 9.3 23.4 2.9 8.1 23.4 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Borrelia_P83 PF05262.11 EAY00152.1 - 2.1 6.8 33.5 3 6.2 33.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LAP1C PF05609.12 EAY00152.1 - 2.8 6.9 28.6 4.4 6.3 28.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MDM1 PF15501.6 EAY00152.1 - 5.7 6.0 38.7 8.3 5.4 38.7 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 Plasmodium_Vir PF05795.11 EAY00152.1 - 8.2 5.7 27.6 23 4.2 26.1 2.1 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_M60 PF13402.6 EAY00153.1 - 7.8e-76 255.1 0.1 1e-75 254.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 EAY00153.1 - 2.7e-28 98.0 0.2 4.6e-28 97.3 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PI3_PI4_kinase PF00454.27 EAY00154.1 - 2.4e-51 175.0 1.4 5.2e-51 173.9 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAY00154.1 - 3.4e-24 85.7 4.5 3.4e-24 85.7 4.5 3.9 2 1 1 3 3 3 1 FAT domain FRB_dom PF08771.11 EAY00154.1 - 3.2e-09 37.1 2.1 1.5e-08 34.9 0.7 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EAY00154.1 - 1e-08 34.8 0.7 8.9e-08 31.8 0.1 2.5 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 EAY00154.1 - 4.4e-05 23.4 11.7 0.00022 21.2 0.3 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EAY00154.1 - 0.0012 19.2 0.2 1.9 8.9 0.0 4.3 3 1 1 4 4 4 1 HEAT repeats XG_FTase PF03254.13 EAY00154.1 - 0.0075 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase TPR_14 PF13428.6 EAY00154.1 - 0.0082 16.9 4.0 0.75 10.8 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF1904 PF08921.11 EAY00154.1 - 0.0095 16.2 0.2 1.3 9.4 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1904) TPR_19 PF14559.6 EAY00154.1 - 0.39 11.3 2.5 9.1 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_57 PF03065.15 EAY00155.1 - 0.22 10.7 10.7 6.1 5.9 10.7 2.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Gly_rich PF12810.7 EAY00156.1 - 6.1e-39 134.4 55.6 7.3e-39 134.1 55.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Pkinase PF00069.25 EAY00157.1 - 3.2e-20 72.6 0.0 6.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00157.1 - 6.7e-13 48.5 0.0 2.3e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Adaptin_N PF01602.20 EAY00157.1 - 0.0007 18.3 5.4 0.0014 17.3 5.4 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HATPase_c_3 PF13589.6 EAY00158.1 - 0.00058 19.7 0.0 0.00058 19.7 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAY00158.1 - 0.0021 18.6 0.0 0.0073 16.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase PF01425.21 EAY00158.1 - 9.4 5.1 10.7 3.2 6.6 4.2 2.1 2 0 0 2 2 2 0 Amidase LCAT PF02450.15 EAY00159.1 - 1.2e-24 87.2 0.0 6.4e-23 81.5 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAY00159.1 - 0.0016 17.7 0.0 0.0036 16.6 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UPF0565 PF10561.9 EAY00159.1 - 0.07 12.3 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 zf-CCCH_3 PF15663.5 EAY00159.1 - 0.078 13.2 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger containing family PGAP1 PF07819.13 EAY00159.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein VirJ PF06057.11 EAY00159.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 EAY00159.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 EAY00159.1 - 0.2 12.2 0.0 0.28 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_8 PF13855.6 EAY00160.1 - 6.2e-29 99.5 9.6 2e-14 53.1 4.1 4.6 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EAY00160.1 - 7.1e-26 89.9 17.4 5.6e-06 26.6 3.3 5.5 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY00160.1 - 2.8e-21 75.8 8.6 9.5e-13 48.0 0.3 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 EAY00160.1 - 7.9e-09 35.6 0.8 7.9e-09 35.6 0.8 1.9 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EAY00160.1 - 1.2e-05 25.0 8.6 7.3 6.9 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich repeat BUD22 PF09073.10 EAY00160.1 - 0.00056 19.4 26.3 0.00056 19.4 26.3 2.1 2 0 0 2 2 2 2 BUD22 LRR_1 PF00560.33 EAY00160.1 - 0.04 14.4 9.3 37 5.4 0.9 6.2 7 2 1 8 8 8 0 Leucine Rich Repeat CCSAP PF15748.5 EAY00160.1 - 8.7 6.4 30.9 4 7.5 21.6 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Acetyltransf_1 PF00583.25 EAY00161.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAY00161.1 - 4.1e-06 26.8 0.1 5e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAY00161.1 - 0.0024 18.3 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAY00161.1 - 0.0037 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein 14-3-3 PF00244.20 EAY00162.1 - 2e-41 141.9 3.9 2.3e-41 141.7 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein T3SS_TC PF06511.11 EAY00162.1 - 0.0073 15.8 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Type III secretion systems tip complex components TPR_8 PF13181.6 EAY00162.1 - 0.029 14.6 1.0 32 5.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MSC PF09402.10 EAY00163.1 - 8.8e-12 45.1 11.7 5.7e-11 42.5 11.7 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain TMIE PF16038.5 EAY00163.1 - 0.0045 16.8 0.6 0.013 15.3 0.6 1.7 1 0 0 1 1 1 1 TMIE protein Sprouty PF05210.13 EAY00163.1 - 0.014 15.7 0.5 0.014 15.7 0.5 2.1 2 0 0 2 2 2 0 Sprouty protein (Spry) Orf78 PF06024.12 EAY00163.1 - 1.3 9.4 6.3 5.5 7.3 0.7 2.5 2 0 0 2 2 2 0 Orf78 (ac78) PDEase_I PF00233.19 EAY00164.1 - 6.5e-31 107.9 0.2 2.8e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAY00164.1 - 6.3e-15 56.0 0.0 2e-08 35.0 0.0 3.6 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 EAY00164.1 - 7.4e-15 55.5 0.0 0.00014 22.2 0.0 3.9 4 0 0 4 4 4 3 GAF domain DUF948 PF06103.11 EAY00165.1 - 1.7 8.9 18.9 0.69 10.2 0.3 4.5 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 EAY00165.1 - 2 9.1 9.7 84 3.9 0.1 4.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Gly_rich PF12810.7 EAY00166.1 - 1.7e-37 129.7 54.0 2e-37 129.4 54.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY00167.1 - 1.9e-13 50.9 35.3 2.5e-13 50.5 35.3 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY00168.1 - 6.7e-38 131.0 49.1 8e-38 130.7 49.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY00169.1 - 2.1e-38 132.7 58.0 2.5e-38 132.4 58.0 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY00170.1 - 3.6e-34 118.8 54.6 4.5e-34 118.5 54.6 1.1 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY00171.1 - 4.3e-31 108.7 21.4 4.7e-31 108.5 21.4 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank_4 PF13637.6 EAY00172.1 - 5e-64 211.9 15.7 4e-13 49.6 0.1 8.1 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAY00172.1 - 1.4e-59 196.0 15.4 9.3e-09 35.4 0.5 8.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_2 PF12796.7 EAY00172.1 - 2.6e-54 181.8 26.7 3.5e-17 62.8 2.2 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00172.1 - 3.4e-47 152.9 13.5 7e-06 26.0 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAY00172.1 - 2.7e-35 119.9 22.9 7.3e-12 45.3 1.5 5.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00172.1 - 1.8e-25 88.7 23.1 7e-25 86.8 5.6 3.9 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAY00172.1 - 0.00062 19.9 0.3 0.39 10.9 0.0 3.7 2 1 1 3 3 3 1 Centrosomal spindle body, CEP44 Ribosomal_S6 PF01250.17 EAY00172.1 - 0.0055 16.9 3.3 7 7.0 0.1 4.0 1 1 3 5 5 5 1 Ribosomal protein S6 CCDC84 PF14968.6 EAY00172.1 - 0.02 14.6 10.6 1.8 8.1 0.3 4.3 1 1 4 5 5 5 0 Coiled coil protein 84 PAZ_siRNAbind PF12212.8 EAY00172.1 - 0.064 13.1 6.2 1.3e+02 2.4 0.0 5.8 2 1 5 7 7 7 0 PAZ domain DUF3718 PF12514.8 EAY00172.1 - 0.16 12.1 17.3 9 6.5 0.3 6.5 4 2 3 7 7 7 0 Protein of unknown function (DUF3718) DUF3447 PF11929.8 EAY00174.1 - 7.6e-06 25.8 0.1 7.6e-06 25.8 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) T5orf172 PF10544.9 EAY00175.1 - 8.7e-07 29.4 0.2 1.8e-06 28.4 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY00176.1 - 4.6e-32 110.2 0.5 1.2e-31 108.9 0.1 1.9 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAY00177.1 - 9.7e-07 28.5 3.4 9.7e-07 28.5 3.4 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00177.1 - 1.5e-06 28.5 0.3 1.2e-05 25.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY00177.1 - 5.1e-05 23.1 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY00177.1 - 0.00018 21.5 3.3 0.00042 20.4 3.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00177.1 - 0.00053 19.8 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00177.1 - 0.0011 18.9 0.6 0.002 18.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00177.1 - 0.0018 17.9 0.6 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00177.1 - 0.0064 16.8 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAY00177.1 - 0.051 14.0 0.1 0.65 10.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAY00177.1 - 0.059 12.9 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAY00177.1 - 0.067 12.6 0.1 0.15 11.5 0.1 1.8 1 1 0 1 1 1 0 PhoH-like protein DUF4795 PF16043.5 EAY00177.1 - 0.31 10.6 8.4 0.17 11.5 3.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1827 PF08860.10 EAY00177.1 - 0.51 10.6 4.3 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2666 PF10869.8 EAY00177.1 - 2 8.6 14.7 1.4 9.1 2.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2666) DUF4108 PF13390.6 EAY00179.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_D5 PF03288.16 EAY00180.1 - 1.7e-05 25.2 2.9 0.00011 22.6 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAY00180.1 - 0.075 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PRA-PH PF01503.17 EAY00181.1 - 0.057 13.9 0.9 3.9 8.0 2.8 2.4 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Wzy_C PF04932.15 EAY00184.1 - 0.074 12.7 0.5 0.074 12.7 0.5 1.1 1 0 0 1 1 1 0 O-Antigen ligase MttA_Hcf106 PF02416.16 EAY00184.1 - 0.3 10.5 0.3 0.3 10.5 0.3 2.1 2 0 0 2 2 2 0 mttA/Hcf106 family Ank_4 PF13637.6 EAY00185.1 - 7.6e-45 150.7 15.7 1.3e-09 38.4 0.1 9.2 4 3 6 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00185.1 - 1.3e-42 144.2 10.6 1.2e-13 51.5 0.2 6.4 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00185.1 - 8.1e-39 130.4 9.8 2.7e-06 27.6 0.3 8.9 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 EAY00185.1 - 3.7e-35 116.0 19.5 6.3e-06 26.1 0.1 11.3 11 1 1 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 EAY00185.1 - 8.7e-35 118.3 7.1 2.1e-08 34.3 0.0 7.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00185.1 - 3.6e-23 81.3 1.7 3.6e-23 81.3 1.7 5.6 4 2 0 5 5 5 2 Domain of unknown function (DUF3447) DUF3718 PF12514.8 EAY00185.1 - 0.039 14.1 4.1 25 5.1 0.0 5.9 5 1 0 6 6 6 0 Protein of unknown function (DUF3718) HAD_2 PF13419.6 EAY00186.1 - 5.1e-26 91.8 0.0 7.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAY00186.1 - 2.3e-17 64.0 0.0 2.3e-13 50.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAY00186.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAY00186.1 - 0.0018 18.7 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UCH PF00443.29 EAY00187.1 - 7.9e-34 117.3 0.0 2.7e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAY00187.1 - 5.5e-05 22.9 0.4 0.00037 20.2 0.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT_2 PF13646.6 EAY00187.1 - 0.1 13.0 0.6 9.1 6.8 0.0 4.5 6 0 0 6 6 6 0 HEAT repeats PolyA_pol PF01743.20 EAY00188.1 - 1.6e-23 83.5 0.1 3.9e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAY00188.1 - 0.0039 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_5 PF13306.6 EAY00189.1 - 9.1e-50 167.9 26.3 1.4e-18 67.1 9.0 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00189.1 - 7.3e-11 41.7 0.1 0.13 12.0 0.3 4.9 4 1 0 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 EAY00190.1 - 1.9e-67 225.1 35.3 1.3e-24 86.6 5.6 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00190.1 - 2.3e-10 40.1 1.5 0.11 12.3 0.1 6.2 4 2 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EAY00190.1 - 0.00021 21.6 1.5 4.9 7.7 0.2 5.4 4 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EAY00191.1 - 8.2e-41 139.0 21.2 6.5e-23 81.1 9.8 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00191.1 - 0.00016 21.3 4.6 0.15 11.8 0.1 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 EAY00192.1 - 4.1e-206 673.4 172.5 2.2e-30 105.2 7.3 9.7 2 2 8 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00192.1 - 8.6e-17 60.7 19.1 0.012 15.3 0.1 13.6 8 3 9 17 17 17 7 Leucine rich repeat LRR_4 PF12799.7 EAY00192.1 - 9.3e-06 25.9 11.8 6.6 7.3 0.0 10.8 13 2 1 14 14 14 2 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAY00192.1 - 0.0093 16.1 12.3 1.8e+02 2.4 0.4 8.5 7 4 1 8 8 8 0 FNIP Repeat DUF1308 PF07000.11 EAY00192.1 - 0.11 12.5 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) SHIPPO-rpt PF07004.12 EAY00193.1 - 2.9e-25 88.0 58.5 0.00017 22.4 3.3 11.7 12 0 0 12 12 12 9 Sperm-tail PG-rich repeat RRM_1 PF00076.22 EAY00194.1 - 1.8e-13 50.1 0.0 2.5e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAY00194.1 - 0.0073 16.2 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF4140 PF13600.6 EAY00194.1 - 0.13 12.7 0.2 0.13 12.7 0.2 4.2 3 2 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 EAY00194.1 - 0.62 9.4 12.0 1.1 8.6 11.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 EAY00194.1 - 0.62 10.3 15.9 1.2 9.4 2.3 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Beach PF02138.18 EAY00197.1 - 1e-97 326.8 0.3 2.5e-97 325.6 0.3 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAY00197.1 - 1.8e-09 37.3 0.6 1.8e-09 37.3 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAY00197.1 - 7.8e-08 32.3 0.5 2.1e-07 30.9 0.5 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EAY00197.1 - 9.3e-06 25.9 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Apt1 PF10351.9 EAY00198.1 - 0.00025 20.1 5.7 0.00029 19.8 5.7 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 EAY00198.1 - 0.0091 15.9 10.7 0.012 15.5 10.7 1.1 1 0 0 1 1 1 1 SPX domain Zip PF02535.22 EAY00198.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MID_MedPIWI PF18296.1 EAY00198.1 - 0.13 12.1 9.0 0.21 11.4 9.0 1.4 1 0 0 1 1 1 0 MID domain of medPIWI RIFIN PF02009.16 EAY00198.1 - 0.15 12.0 7.2 1.5 8.6 0.7 2.3 2 0 0 2 2 2 0 Rifin SOG2 PF10428.9 EAY00198.1 - 0.4 9.8 19.5 0.55 9.4 19.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GEMIN8 PF15348.6 EAY00198.1 - 0.5 10.6 4.3 0.84 9.9 4.3 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Ndc1_Nup PF09531.10 EAY00198.1 - 1.1 7.9 8.6 1.5 7.4 8.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWI-SNF_Ssr4 PF08549.10 EAY00198.1 - 1.8 7.1 8.1 2.4 6.7 8.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RNA_pol_Rpc4 PF05132.14 EAY00198.1 - 1.9 8.9 7.6 3.3 8.1 7.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pol_alpha_B_N PF08418.10 EAY00198.1 - 2.5 8.0 14.3 4.4 7.2 14.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF515 PF04415.12 EAY00198.1 - 5.3 5.3 26.0 0.7 8.2 19.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Macoilin PF09726.9 EAY00198.1 - 6.1 5.3 14.3 8 4.9 14.3 1.1 1 0 0 1 1 1 0 Macoilin family ASD2 PF08687.11 EAY00198.1 - 6.7 6.2 5.9 11 5.5 5.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF4614 PF15391.6 EAY00198.1 - 7.2 6.6 25.6 12 5.8 25.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) HIP1_clath_bdg PF16515.5 EAY00199.1 - 0.0058 17.2 13.5 0.0058 17.2 13.5 9.2 3 3 5 8 8 8 1 Clathrin-binding domain of Huntingtin-interacting protein 1 PSD2 PF07624.11 EAY00199.1 - 0.68 9.8 4.1 17 5.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1585) ATG16 PF08614.11 EAY00199.1 - 6.5 6.9 132.4 0.44 10.7 19.2 7.7 3 1 4 7 7 7 0 Autophagy protein 16 (ATG16) ubiquitin PF00240.23 EAY00200.1 - 6.2e-13 48.3 0.2 1.8e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.31 EAY00200.1 - 0.00093 19.1 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.19 EAY00200.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HOIP-UBA PF16678.5 EAY00200.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 HOIP UBA domain pair FlbD PF06289.11 EAY00200.1 - 0.02 14.5 0.8 0.44 10.2 0.2 2.5 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins TBK1_ULD PF18396.1 EAY00200.1 - 0.023 14.6 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAY00200.1 - 0.039 14.4 0.5 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain PTPS_related PF10131.9 EAY00201.1 - 0.034 12.5 1.0 0.045 12.1 1.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF4407 PF14362.6 EAY00201.1 - 4.1 6.7 5.0 5.6 6.2 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CS PF04969.16 EAY00202.1 - 1e-06 29.7 0.2 1.7e-06 29.0 0.2 1.4 1 0 0 1 1 1 1 CS domain SRA PF18491.1 EAY00202.1 - 0.064 13.4 2.2 0.092 12.9 2.2 1.3 1 0 0 1 1 1 0 SET and RING associated domain Ank_2 PF12796.7 EAY00204.1 - 6.6e-25 87.5 0.3 1.8e-11 44.4 0.0 4.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00204.1 - 6.3e-18 64.9 0.6 4e-08 33.7 0.1 5.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00204.1 - 8.2e-17 59.6 0.1 0.00014 22.0 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAY00204.1 - 1.2e-16 60.5 0.6 8.3e-06 26.0 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY00204.1 - 2.8e-13 49.6 0.0 0.009 16.4 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat DUF2748 PF10871.8 EAY00204.1 - 0.027 13.1 0.1 0.051 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) DUF3447 PF11929.8 EAY00204.1 - 0.062 13.3 2.4 3.7 7.6 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) PPTA PF01239.22 EAY00205.1 - 8.3e-15 54.0 12.4 2.4e-05 23.9 0.6 6.1 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat Rrn6 PF10214.9 EAY00206.1 - 0.014 14.0 7.4 0.021 13.4 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2151 PF10221.9 EAY00206.1 - 1.4 7.4 10.5 1.8 7.1 9.6 1.5 1 1 0 1 1 1 0 Cell cycle and development regulator EOS1 PF12326.8 EAY00206.1 - 4.8 7.1 4.6 11 5.9 4.6 1.6 1 0 0 1 1 1 0 N-glycosylation protein UQ_con PF00179.26 EAY00207.1 - 2.5e-39 134.2 0.0 2.8e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAY00207.1 - 9.8e-05 22.1 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EAY00207.1 - 0.025 14.5 0.2 0.039 13.8 0.2 1.4 1 1 0 1 1 1 0 UEV domain IF4E PF01652.18 EAY00208.1 - 1.4e-26 93.2 3.2 1.6e-26 93.0 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPR_2 PF07719.17 EAY00209.1 - 2.8e-11 42.6 9.6 0.00014 21.7 0.2 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAY00209.1 - 1.2e-09 38.6 1.2 0.00045 20.7 0.0 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAY00209.1 - 5.6e-08 32.3 10.7 6.3e-06 25.8 0.7 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAY00209.1 - 2.3e-06 27.9 7.6 1.8 9.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAY00209.1 - 5e-06 27.1 3.4 0.38 11.4 0.5 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAY00209.1 - 9.7e-06 26.0 0.5 5.4 8.1 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAY00209.1 - 1.6e-05 24.7 12.7 0.0014 18.6 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAY00209.1 - 0.00041 20.6 6.8 1.6 9.1 0.0 5.3 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAY00209.1 - 0.0014 18.5 1.6 0.21 11.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 EAY00209.1 - 0.0022 17.1 0.5 0.41 9.6 0.0 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 EAY00209.1 - 0.0077 16.5 12.0 0.086 13.3 0.4 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 EAY00209.1 - 0.0086 15.5 0.8 0.091 12.2 0.8 2.5 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 EAY00209.1 - 0.05 13.3 7.7 0.74 9.6 1.3 4.0 3 2 2 5 5 5 0 TPR repeat TPR_9 PF13371.6 EAY00209.1 - 0.092 12.9 0.1 2.1 8.6 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Shisa PF13908.6 EAY00210.1 - 2.9e-06 27.7 3.5 4.8e-06 27.0 3.5 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EAY00210.1 - 4.9e-06 26.5 0.1 7.9e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Prominin PF05478.11 EAY00210.1 - 0.00042 18.4 2.4 0.00055 18.1 2.4 1.1 1 0 0 1 1 1 1 Prominin EphA2_TM PF14575.6 EAY00210.1 - 0.001 19.9 0.8 0.002 18.9 0.8 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 EAY00210.1 - 0.0052 17.1 2.4 0.0093 16.3 2.4 1.4 1 0 0 1 1 1 1 Commissureless TMEM132D_C PF15706.5 EAY00210.1 - 0.0061 16.3 0.8 0.011 15.4 0.8 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MLANA PF14991.6 EAY00210.1 - 0.015 15.6 0.1 0.041 14.2 0.1 1.7 2 0 0 2 2 2 0 Protein melan-A Tweety PF04906.13 EAY00210.1 - 0.018 13.7 2.9 0.024 13.3 2.9 1.1 1 0 0 1 1 1 0 Tweety DUF3827 PF12877.7 EAY00210.1 - 0.021 13.2 2.5 0.029 12.8 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Protocadherin PF08374.11 EAY00210.1 - 0.023 14.7 0.2 0.039 13.9 0.2 1.3 1 0 0 1 1 1 0 Protocadherin Glycophorin_A PF01102.18 EAY00210.1 - 0.089 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A DUF5385 PF17359.2 EAY00210.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) CYYR1 PF10873.8 EAY00210.1 - 0.38 11.2 6.9 3.1 8.2 4.2 2.3 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Orthoreo_P10 PF07204.11 EAY00210.1 - 1.2 9.1 11.1 4.4 7.3 11.1 1.9 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MscL PF01741.18 EAY00211.1 - 0.0018 18.6 1.7 0.0039 17.5 1.6 1.8 1 1 1 2 2 2 1 Large-conductance mechanosensitive channel, MscL ER_lumen_recept PF00810.18 EAY00211.1 - 0.02 15.7 3.0 0.021 15.6 1.5 1.7 2 0 0 2 2 2 0 ER lumen protein retaining receptor Tropomyosin_1 PF12718.7 EAY00212.1 - 0.0008 19.6 18.1 0.0008 19.6 18.1 8.8 5 2 2 7 7 7 2 Tropomyosin like SlyX PF04102.12 EAY00212.1 - 0.0016 19.1 1.0 0.0016 19.1 1.0 12.7 6 5 6 12 12 12 2 SlyX Filament PF00038.21 EAY00212.1 - 0.0035 17.0 139.3 0.027 14.0 8.9 8.2 2 1 5 8 8 8 6 Intermediate filament protein Snapin_Pallidin PF14712.6 EAY00212.1 - 0.018 15.5 4.9 0.018 15.5 4.9 12.2 5 4 7 14 14 14 0 Snapin/Pallidin DUF226 PF02890.14 EAY00213.1 - 0.091 12.8 0.0 0.099 12.7 0.0 1.1 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Ank_4 PF13637.6 EAY00215.1 - 3.2e-46 155.1 6.0 2e-14 53.7 0.1 4.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00215.1 - 1.1e-34 117.4 9.0 4e-09 36.5 0.1 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 EAY00215.1 - 1.9e-31 108.4 11.6 2.5e-18 66.4 4.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00215.1 - 2.9e-28 97.5 8.5 2e-12 47.1 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00215.1 - 3e-25 85.5 3.2 7.6e-06 25.9 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat YcxB PF14317.6 EAY00215.1 - 6.5e-06 25.8 0.0 0.25 11.1 0.0 3.8 2 1 2 4 4 4 2 YcxB-like protein ThiS-like PF14453.6 EAY00215.1 - 0.00065 19.7 2.8 1.1 9.4 0.1 3.9 1 1 3 4 4 4 2 ThiS-like ubiquitin MetallophosN PF16371.5 EAY00215.1 - 0.0032 17.7 0.0 4 7.8 0.0 3.1 1 1 2 3 3 3 1 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAY00215.1 - 0.016 15.4 0.1 61 4.0 0.0 3.8 1 1 4 5 5 5 0 Pleckstrin homology domain CEP44 PF15007.6 EAY00215.1 - 0.018 15.2 0.1 8 6.6 0.0 2.6 2 1 0 2 2 2 0 Centrosomal spindle body, CEP44 3Beta_HSD PF01073.19 EAY00215.1 - 0.12 11.4 4.5 0.55 9.2 0.9 2.7 1 1 2 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_4 PF13637.6 EAY00216.1 - 3.3e-34 116.8 8.4 9.4e-11 42.0 0.1 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00216.1 - 1.3e-32 110.8 4.9 9.7e-06 25.8 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 EAY00216.1 - 1.3e-29 102.6 9.7 2.8e-16 59.9 3.2 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00216.1 - 1e-21 74.7 1.9 0.00019 21.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAY00216.1 - 1.7e-19 69.6 1.9 2.5e-09 37.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAY00216.1 - 0.00028 21.1 0.0 1.2 9.4 0.0 3.8 1 1 3 4 4 4 1 N terminal of Calcineurin-like phosphoesterase NPHI_C PF08469.10 EAY00216.1 - 0.018 15.0 4.2 0.28 11.1 0.2 2.5 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal PH_8 PF15409.6 EAY00216.1 - 0.02 15.2 4.6 12 6.3 0.0 4.0 1 1 3 4 4 4 0 Pleckstrin homology domain DUF3895 PF13034.6 EAY00216.1 - 0.41 10.7 5.4 14 5.7 0.1 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF3895) DUF3447 PF11929.8 EAY00217.1 - 3.4e-40 135.8 5.9 3.4e-40 135.8 5.9 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00217.1 - 7.4e-12 45.7 0.7 1.9e-06 28.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00217.1 - 5.5e-11 42.8 0.5 1.5e-06 28.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00217.1 - 1.4e-09 37.4 1.3 0.00016 21.9 0.0 5.1 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 EAY00217.1 - 1.4e-08 34.8 0.2 2.6e-05 24.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAY00217.1 - 1.9e-07 31.2 0.0 1.6e-05 25.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Kinesin PF00225.23 EAY00218.1 - 5.1e-44 150.6 0.1 1.5e-43 149.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAY00218.1 - 1e-14 54.7 1.9 2.6e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding Lectin_N PF03954.14 EAY00218.1 - 1.2 8.9 6.0 0.85 9.4 0.2 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Phlebovirus_NSM PF07246.11 EAY00218.1 - 7.6 5.8 17.4 0.41 10.0 11.3 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Tubulin_C PF03953.17 EAY00219.1 - 3.3e-16 59.6 0.0 3.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin C-terminal domain Gly_rich PF12810.7 EAY00221.1 - 2.1e-20 73.7 27.2 2.4e-20 73.5 27.2 1.0 1 0 0 1 1 1 1 Glycine rich protein RhoGEF PF00621.20 EAY00222.1 - 1.9e-29 103.2 4.6 3.8e-29 102.2 0.2 2.3 2 0 0 2 2 2 1 RhoGEF domain Transposase_24 PF03004.14 EAY00222.1 - 0.054 13.6 1.4 0.092 12.9 0.6 1.8 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Ank_2 PF12796.7 EAY00223.1 - 2.1e-63 210.9 31.6 2.4e-13 50.5 2.4 7.5 3 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00223.1 - 3.2e-59 196.2 19.3 3.5e-09 36.7 0.6 9.1 3 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00223.1 - 1.3e-54 181.8 19.8 8.4e-13 48.6 0.2 10.9 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00223.1 - 1.6e-52 169.3 18.4 0.00014 22.0 0.1 13.9 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 EAY00223.1 - 4.5e-45 150.2 25.0 2.4e-05 24.6 0.2 12.9 13 0 0 13 13 13 12 Ankyrin repeat DUF3447 PF11929.8 EAY00223.1 - 4.9e-21 74.5 7.2 4.9e-21 74.5 7.2 6.4 6 2 3 9 9 9 1 Domain of unknown function (DUF3447) SRP_TPR_like PF17004.5 EAY00223.1 - 0.22 11.5 3.7 0.25 11.3 2.2 1.8 2 0 0 2 2 2 0 Putative TPR-like repeat BATS PF06968.13 EAY00224.1 - 4.3e-27 94.1 0.0 1.1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EAY00224.1 - 3.7e-10 40.4 0.1 9.6e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EAY00224.1 - 0.11 12.8 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain XdhC_C PF13478.6 EAY00224.1 - 0.19 12.2 0.0 0.69 10.4 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Peptidase_C1 PF00112.23 EAY00225.1 - 1.7e-52 178.6 3.6 1.9e-52 178.5 3.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAY00225.1 - 0.035 12.9 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family DUF4234 PF14018.6 EAY00226.1 - 3.9 7.7 9.8 29 4.9 9.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) FtsX PF02687.21 EAY00226.1 - 6.8 7.2 17.1 14 6.2 8.0 2.3 1 1 1 2 2 2 0 FtsX-like permease family LRR_5 PF13306.6 EAY00227.1 - 1e-128 423.1 53.8 5.6e-40 136.3 8.5 4.4 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00227.1 - 3e-19 68.5 0.0 0.00053 19.7 0.2 8.0 3 2 6 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 EAY00227.1 - 5e-08 33.1 3.6 1.6 9.3 0.0 8.5 7 2 4 11 11 11 2 Leucine Rich repeats (2 copies) MatB PF16449.5 EAY00227.1 - 0.13 12.0 1.2 9.4 6.0 0.0 3.6 4 0 0 4 4 4 0 Fimbrillin MatB DUF1699 PF08004.11 EAY00227.1 - 1.1 8.9 3.4 8.4 6.1 0.1 4.0 3 3 3 6 6 6 0 Protein of unknown function (DUF1699) DUF4106 PF13388.6 EAY00228.1 - 1.1e-126 423.5 3.9 1.4e-126 423.1 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAY00228.1 - 0.0042 17.4 0.2 0.3 11.4 0.3 2.3 2 1 0 2 2 2 1 Kidney androgen-regulated VP4_2 PF08935.10 EAY00228.1 - 0.08 13.5 0.7 0.18 12.4 0.7 1.6 1 0 0 1 1 1 0 Viral protein VP4 subunit PRA-PH PF01503.17 EAY00229.1 - 3.8 8.0 5.6 4.3 7.9 2.8 2.2 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase PTR PF12789.7 EAY00231.1 - 1.1e-22 79.8 16.4 2.8e-16 59.3 2.0 3.8 5 0 0 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAY00231.1 - 0.075 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PSP PF04046.16 EAY00233.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAY00234.1 - 1.3e-120 394.2 0.3 8.3e-21 74.4 0.1 6.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00234.1 - 5.6e-61 200.5 0.1 9.3e-06 25.9 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.6 EAY00234.1 - 2.2e-60 200.3 0.1 2.3e-11 44.0 0.0 8.5 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00234.1 - 8.4e-57 188.5 0.6 5.8e-08 32.9 0.0 10.7 3 2 9 12 12 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00234.1 - 1.1e-52 169.8 0.1 0.00038 20.7 0.0 11.8 11 1 0 11 11 11 9 Ankyrin repeat B5 PF03484.15 EAY00234.1 - 0.00011 22.4 0.5 27 5.1 0.0 7.1 7 2 1 8 8 7 0 tRNA synthetase B5 domain VPS38 PF17649.1 EAY00234.1 - 0.00049 19.1 11.2 0.0007 18.6 11.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 IHO1 PF15771.5 EAY00234.1 - 0.0031 16.4 5.3 0.0043 15.9 5.3 1.1 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 APG6_N PF17675.1 EAY00234.1 - 0.015 15.8 8.6 0.027 15.0 8.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Med4 PF10018.9 EAY00234.1 - 0.022 14.4 4.1 0.034 13.8 4.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Golgin_A5 PF09787.9 EAY00234.1 - 0.055 12.9 11.3 0.081 12.4 11.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Lectin_N PF03954.14 EAY00234.1 - 0.076 12.8 4.9 0.13 12.0 4.9 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain OmpH PF03938.14 EAY00234.1 - 0.12 12.7 9.3 0.2 12.0 9.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FYVE_2 PF02318.16 EAY00234.1 - 0.14 12.4 3.1 0.34 11.1 3.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF641 PF04859.12 EAY00234.1 - 0.14 12.4 6.3 0.29 11.5 6.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc24 PF08286.11 EAY00234.1 - 0.17 12.1 8.0 0.33 11.2 8.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1939 PF09154.10 EAY00234.1 - 0.2 11.9 0.7 2 8.6 0.0 3.0 3 1 1 4 4 3 0 Domain of unknown function (DUF1939) V_ATPase_I PF01496.19 EAY00234.1 - 0.33 8.8 7.8 0.4 8.5 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PsbR PF04725.12 EAY00234.1 - 0.85 10.0 3.4 46 4.4 0.1 3.4 3 1 1 4 4 3 0 Photosystem II 10 kDa polypeptide PsbR DUF4407 PF14362.6 EAY00234.1 - 2.5 7.4 5.8 3.3 7.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GLE1 PF07817.13 EAY00234.1 - 2.8 7.1 7.2 4.6 6.4 7.2 1.2 1 0 0 1 1 1 0 GLE1-like protein TMPIT PF07851.13 EAY00234.1 - 2.9 7.0 8.7 4.3 6.5 8.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EAY00234.1 - 3.9 6.7 9.9 6 6.1 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SWIB PF02201.18 EAY00235.1 - 6.4e-05 22.8 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain LRR_5 PF13306.6 EAY00236.1 - 6.1e-113 372.2 99.6 6e-26 90.9 7.4 7.4 3 2 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00236.1 - 4.3e-20 71.2 2.5 6.6e-05 22.6 0.0 10.3 10 1 0 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 EAY00236.1 - 3.4e-07 30.5 0.1 1.3 9.5 0.0 7.2 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) hnRNP_Q_AcD PF18360.1 EAY00237.1 - 0.0013 18.6 0.4 0.017 15.1 0.1 2.8 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain Gly_rich PF12810.7 EAY00238.1 - 2.8e-29 102.8 27.4 3.4e-29 102.5 27.4 1.0 1 0 0 1 1 1 1 Glycine rich protein MHC_I PF00129.18 EAY00239.1 - 0.028 14.0 0.9 0.06 12.9 0.9 1.5 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Nodulin_late PF07127.11 EAY00239.1 - 0.22 11.9 2.4 0.22 11.9 0.4 2.0 2 0 0 2 2 2 0 Late nodulin protein Pkinase PF00069.25 EAY00240.1 - 2.1e-51 174.8 0.1 4.6e-51 173.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00240.1 - 1e-14 54.5 0.0 3.9e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Myb_DNA-binding PF00249.31 EAY00241.1 - 3.9e-27 94.2 1.7 2.8e-13 49.8 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00241.1 - 9.6e-24 83.4 7.7 1.6e-15 57.1 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY00241.1 - 1.5e-05 25.0 0.1 0.3 11.1 0.0 3.0 1 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY00241.1 - 0.015 15.2 0.8 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Spore_III_AB PF09548.10 EAY00241.1 - 0.02 15.0 0.1 0.16 12.1 0.0 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EAY00241.1 - 0.27 11.7 11.0 0.88 10.0 2.9 3.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EAY00241.1 - 0.94 9.8 5.4 3 8.2 0.1 2.9 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BTB PF00651.31 EAY00242.1 - 0.0036 17.5 0.3 3.7 7.8 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain PRMT5_TIM PF17285.2 EAY00242.1 - 0.0072 15.6 0.0 0.026 13.7 0.0 1.9 2 0 0 2 2 2 1 PRMT5 TIM barrel domain TarH PF02203.15 EAY00242.1 - 0.018 15.0 4.4 0.046 13.7 4.4 1.7 1 0 0 1 1 1 0 Tar ligand binding domain homologue BLI1 PF17324.2 EAY00242.1 - 0.067 13.9 5.0 0.08 13.6 1.1 2.9 2 0 0 2 2 2 0 BLOC-1 interactor 1 Cucumopine_C PF18631.1 EAY00242.1 - 0.14 12.1 0.1 1.2 9.1 0.0 2.5 3 0 0 3 3 2 0 Cucumopine synthase C-terminal helical bundle domain SlyX PF04102.12 EAY00242.1 - 0.98 10.1 8.7 2 9.1 0.8 3.6 3 0 0 3 3 3 0 SlyX KxDL PF10241.9 EAY00242.1 - 1.1 9.6 7.3 2 8.7 0.0 3.8 3 1 1 4 4 4 0 Uncharacterized conserved protein AATF-Che1 PF13339.6 EAY00242.1 - 1.2 9.8 7.7 0.14 12.8 1.5 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor EcoEI_R_C PF08463.10 EAY00242.1 - 1.8 8.7 12.2 8.3 6.5 0.1 3.6 3 1 0 3 3 3 0 EcoEI R protein C-terminal UPF0242 PF06785.11 EAY00242.1 - 2.2 8.3 16.2 4 7.5 0.4 3.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MctB PF11382.8 EAY00242.1 - 2.3 7.9 4.8 0.68 9.6 0.2 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB TBCA PF02970.16 EAY00242.1 - 4.1 7.8 10.0 3.2 8.1 1.3 3.8 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF16 PF01519.16 EAY00242.1 - 7 7.2 18.2 1.4 9.5 2.0 3.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 EAY00242.1 - 8.7 6.9 11.2 2.1 8.8 0.1 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.11 EAY00242.1 - 9.2 6.3 7.1 1.6 8.8 0.5 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RICTOR_M PF14666.6 EAY00243.1 - 0.023 14.5 0.7 0.52 10.1 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain DUF3361 PF11841.8 EAY00243.1 - 0.13 12.2 3.5 5 7.0 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) Bromo_TP_like PF17027.5 EAY00245.1 - 0.0018 18.4 0.0 0.0049 17.0 0.0 1.7 1 0 0 1 1 1 1 Histone-fold protein DUF2373 PF10180.9 EAY00245.1 - 0.19 11.6 1.1 0.61 10.0 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DUF3425 PF11905.8 EAY00245.1 - 0.44 10.5 3.5 1.9 8.5 3.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) MatE PF01554.18 EAY00247.1 - 1.7e-25 89.5 24.3 2.7e-19 69.4 4.9 2.7 3 0 0 3 3 3 2 MatE DUF870 PF05912.11 EAY00248.1 - 0.055 13.5 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Ank_2 PF12796.7 EAY00249.1 - 3.4e-45 152.5 9.2 2.6e-15 56.8 0.2 5.5 3 3 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00249.1 - 1.2e-44 148.8 8.7 4.8e-05 23.6 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAY00249.1 - 6.4e-42 141.1 12.7 6.2e-09 36.0 0.1 7.1 2 2 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00249.1 - 1e-41 136.1 5.3 5.6e-05 23.2 0.0 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAY00249.1 - 2.2e-41 139.7 1.7 7.1e-11 42.4 0.0 7.8 4 3 4 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00249.1 - 5e-19 68.0 6.8 5e-19 68.0 6.8 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00250.1 - 1.6e-48 163.2 0.2 1.5e-13 51.1 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00250.1 - 3.3e-33 113.6 0.9 2e-10 41.0 0.2 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00250.1 - 1.6e-25 88.8 0.4 3.7e-07 30.3 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00250.1 - 3.6e-25 85.3 0.5 1.4e-05 25.1 0.0 6.2 8 0 0 8 8 6 4 Ankyrin repeat Ank PF00023.30 EAY00250.1 - 3.3e-22 77.9 0.7 3e-05 24.3 0.1 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ax_dynein_light PF10211.9 EAY00250.1 - 0.0046 16.9 2.1 0.0096 15.9 2.1 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain bZIP_1 PF00170.21 EAY00250.1 - 0.011 15.8 5.1 0.011 15.8 5.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.9 EAY00250.1 - 0.026 13.6 3.1 0.041 13.0 3.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 L_lactis_ph-MCP PF06673.11 EAY00250.1 - 0.026 13.5 4.3 0.046 12.7 4.3 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Shugoshin_N PF07558.11 EAY00250.1 - 0.027 14.3 5.1 0.062 13.2 5.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 EAY00250.1 - 0.029 14.8 1.7 0.029 14.8 1.7 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cas_Csa5 PF09702.10 EAY00250.1 - 0.037 14.3 0.3 0.48 10.7 0.0 2.5 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) YabA PF06156.13 EAY00250.1 - 0.039 14.6 2.9 0.039 14.6 2.9 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 EAY00250.1 - 0.081 12.7 4.7 0.2 11.4 4.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Swi5 PF07061.11 EAY00250.1 - 0.35 11.0 5.2 0.85 9.7 3.3 2.5 3 0 0 3 3 3 0 Swi5 TSC22 PF01166.18 EAY00250.1 - 0.49 10.7 4.1 1 9.7 4.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 EAY00250.1 - 2.6 8.2 12.4 19 5.4 6.7 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Synaptobrevin PF00957.21 EAY00251.1 - 1.2e-27 95.5 4.4 2.2e-27 94.6 4.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAY00251.1 - 2.2e-10 40.4 0.0 3.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Prominin PF05478.11 EAY00251.1 - 0.0009 17.3 0.4 0.0011 17.1 0.4 1.1 1 0 0 1 1 1 1 Prominin Ferlin_C PF16165.5 EAY00251.1 - 0.0048 16.8 0.2 0.0079 16.1 0.2 1.3 1 0 0 1 1 1 1 Ferlin C-terminus RIFIN PF02009.16 EAY00251.1 - 0.0065 16.4 2.7 0.0075 16.2 2.7 1.1 1 0 0 1 1 1 1 Rifin Glyco_transf_15 PF01793.16 EAY00251.1 - 0.014 14.6 0.5 0.018 14.3 0.5 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase STALD PF18185.1 EAY00251.1 - 0.069 12.5 0.7 1.2 8.5 0.0 2.3 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family Orf78 PF06024.12 EAY00251.1 - 0.18 12.1 0.7 0.53 10.6 0.7 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Tweety PF04906.13 EAY00251.1 - 5.7 5.5 9.7 22 3.6 9.7 1.7 1 1 0 1 1 1 0 Tweety PLAT PF01477.23 EAY00252.1 - 0.019 15.6 0.1 0.031 14.9 0.1 1.3 1 0 0 1 1 1 0 PLAT/LH2 domain GTSE1_N PF15259.6 EAY00252.1 - 0.04 14.1 0.5 0.062 13.5 0.5 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Herpes_U30 PF04523.13 EAY00252.1 - 0.046 11.6 0.1 0.056 11.3 0.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 HTH_38 PF13936.6 EAY00252.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.6 EAY00252.1 - 0.055 13.7 0.5 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF5357 PF17310.2 EAY00252.1 - 0.12 10.9 1.0 0.15 10.6 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) HTH_40 PF14493.6 EAY00252.1 - 0.15 12.5 0.6 0.24 11.9 0.6 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TCR PF03638.15 EAY00253.1 - 4.5e-06 26.9 27.9 6.9e-06 26.3 27.9 1.3 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Phage_TAC_12 PF12363.8 EAY00253.1 - 0.016 15.6 0.3 0.026 14.9 0.3 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC WGG PF10273.9 EAY00253.1 - 0.1 13.3 0.1 0.17 12.6 0.1 1.5 1 1 0 1 1 1 0 Pre-rRNA-processing protein TSR2 SAC3 PF12209.8 EAY00253.1 - 0.18 12.0 1.9 0.58 10.4 0.2 2.4 1 1 1 2 2 2 0 Leucine permease transcriptional regulator helical domain PSP PF04046.16 EAY00254.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAY00255.1 - 0.037 14.5 0.5 0.094 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAY00255.1 - 0.77 9.8 3.8 9.8 6.3 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein PTR PF12789.7 EAY00256.1 - 6.4e-58 192.7 38.3 1.6e-32 111.3 18.4 5.3 4 2 1 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAY00256.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PH_TFIIH PF08567.11 EAY00256.1 - 1.2 9.5 5.3 15 6.0 0.2 3.8 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF3839 PF12943.7 EAY00257.1 - 2.7e-157 521.4 13.8 3.4e-157 521.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY00257.1 - 0.17 11.7 1.4 0.49 10.2 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY00257.1 - 2.5 8.6 8.1 1.6 9.2 0.7 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SAP PF02037.27 EAY00259.1 - 0.034 13.9 0.1 0.066 13.0 0.0 1.6 2 0 0 2 2 2 0 SAP domain zf-RING_2 PF13639.6 EAY00261.1 - 5e-12 45.9 6.0 8.5e-12 45.2 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAY00261.1 - 4.1e-07 30.2 8.8 6e-06 26.4 8.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAY00261.1 - 4.9e-06 26.3 5.9 9.4e-06 25.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAY00261.1 - 1.1e-05 25.2 3.7 2e-05 24.5 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAY00261.1 - 1.5e-05 24.7 2.9 2.5e-05 24.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAY00261.1 - 1.7e-05 24.6 4.8 3.1e-05 23.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAY00261.1 - 5.3e-05 22.9 4.5 5.3e-05 22.9 4.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EAY00261.1 - 7.3e-05 22.3 2.7 0.00014 21.4 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EAY00261.1 - 0.01 15.9 8.3 0.074 13.1 8.3 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAY00261.1 - 0.011 15.7 7.5 0.024 14.7 7.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 EAY00261.1 - 0.037 14.2 3.8 0.091 12.9 3.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EAY00261.1 - 0.17 12.2 4.1 0.3 11.4 4.1 1.5 1 0 0 1 1 1 0 RING-like domain SHR3_chaperone PF08229.11 EAY00261.1 - 0.19 10.7 0.9 0.26 10.2 0.9 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Prok-RING_4 PF14447.6 EAY00261.1 - 0.3 11.0 7.8 0.12 12.2 4.8 2.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EAY00261.1 - 1.3 9.3 8.4 15 5.8 8.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EAY00261.1 - 2.9 8.0 10.1 13 5.9 10.0 2.1 1 1 0 1 1 1 0 Zinc-finger Myb_DNA-binding PF00249.31 EAY00264.1 - 1.1e-26 92.8 2.5 3.2e-12 46.4 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00264.1 - 4.5e-23 81.3 2.1 5.2e-15 55.4 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY00264.1 - 5.9e-09 35.9 0.1 0.00096 19.2 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY00264.1 - 0.012 15.5 0.4 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAY00264.1 - 0.14 12.4 0.6 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAY00264.1 - 0.78 10.2 5.8 1.7 9.1 0.7 3.2 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4107 PF13389.6 EAY00265.1 - 2.3e-33 115.6 2.2 3.3e-33 115.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DNA_pol_B_2 PF03175.13 EAY00267.1 - 8.3e-11 41.4 3.5 2.4e-10 39.9 2.4 2.1 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EAY00267.1 - 0.098 11.3 1.5 4 6.0 1.3 3.0 2 1 0 2 2 2 0 DNA polymerase family B DUF5106 PF17127.4 EAY00267.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PapD_N PF00345.20 EAY00268.1 - 0.044 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAY00268.1 - 0.085 12.9 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAY00269.1 - 0.018 15.4 0.6 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY00269.1 - 3.1 7.8 6.6 3.2 7.8 6.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAY00270.1 - 0.009 16.0 0.3 0.013 15.5 0.3 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAY00271.1 - 0.088 12.8 9.3 0.14 12.2 9.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY00272.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF659 PF04937.15 EAY00273.1 - 0.012 15.5 0.2 0.047 13.5 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF 659) Pkinase PF00069.25 EAY00275.1 - 3e-55 187.4 0.9 3.8e-55 187.1 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00275.1 - 1.5e-32 112.9 0.1 1.9e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00275.1 - 4.9e-10 39.2 0.1 1.3e-08 34.5 0.0 2.5 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAY00275.1 - 6.5e-05 21.9 0.2 9.5e-05 21.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY00275.1 - 0.0041 16.5 0.1 0.011 15.1 0.2 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY00275.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Podoplanin PF05808.11 EAY00277.1 - 1.4e-08 35.0 0.0 1.6e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 EAY00277.1 - 1.6e-05 25.1 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DUF4690 PF15756.5 EAY00277.1 - 0.00019 21.9 0.0 0.00022 21.8 0.0 1.2 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 EAY00277.1 - 0.00023 20.8 0.4 0.00031 20.4 0.4 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 VSP PF03302.13 EAY00277.1 - 0.0004 19.4 0.4 0.00047 19.1 0.4 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Shisa PF13908.6 EAY00277.1 - 0.0013 19.0 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Syndecan PF01034.20 EAY00277.1 - 0.002 18.0 1.5 0.0036 17.2 1.5 1.4 1 0 0 1 1 1 1 Syndecan domain DUF4366 PF14283.6 EAY00277.1 - 0.0022 18.0 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF5305 PF17231.2 EAY00277.1 - 0.0024 17.3 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) CCSMST1 PF15013.6 EAY00277.1 - 0.0039 17.3 0.6 0.0059 16.7 0.6 1.4 1 1 0 1 1 1 1 CCSMST1 family ATG22 PF11700.8 EAY00277.1 - 0.0063 15.2 0.0 0.0076 14.9 0.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4448 PF14610.6 EAY00277.1 - 0.0064 16.3 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Pox_Ag35 PF03286.14 EAY00277.1 - 0.0077 16.1 0.0 0.0077 16.1 0.0 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Glycophorin_A PF01102.18 EAY00277.1 - 0.0086 16.3 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A YebO PF13974.6 EAY00277.1 - 0.011 15.7 0.7 0.011 15.7 0.7 2.2 2 0 0 2 2 2 0 YebO-like protein DUF2207 PF09972.9 EAY00277.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mid2 PF04478.12 EAY00277.1 - 0.019 14.8 1.8 0.031 14.1 1.3 1.6 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Otopetrin PF03189.13 EAY00277.1 - 0.021 13.7 0.0 0.021 13.7 0.0 1.0 1 0 0 1 1 1 0 Otopetrin ASFV_J13L PF05568.11 EAY00277.1 - 0.032 14.0 0.4 0.045 13.5 0.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 EAY00277.1 - 0.036 14.9 2.3 0.079 13.9 0.6 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2613 PF11021.8 EAY00277.1 - 0.047 13.8 1.6 0.11 12.6 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) RIFIN PF02009.16 EAY00277.1 - 0.051 13.5 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 EAY00277.1 - 0.064 12.1 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless SseC PF04888.12 EAY00277.1 - 0.082 12.5 1.3 0.11 12.1 1.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family AMA-1 PF02430.15 EAY00277.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF5385 PF17359.2 EAY00277.1 - 0.12 11.9 0.2 0.12 11.9 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) MMM1 PF10296.9 EAY00277.1 - 0.13 11.3 0.3 0.13 11.3 0.3 1.7 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Stevor PF17410.2 EAY00277.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Baculo_11_kDa PF06143.11 EAY00277.1 - 0.15 11.6 0.3 0.27 10.8 0.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family MtrF PF09472.10 EAY00277.1 - 0.38 10.2 5.4 1.4 8.4 6.1 1.5 2 0 0 2 2 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ODV-E18 PF10717.9 EAY00277.1 - 0.43 10.5 1.5 0.58 10.1 1.5 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4519 PF15012.6 EAY00277.1 - 1 9.6 8.9 2.7 8.2 8.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) ECSCR PF15820.5 EAY00277.1 - 5.1 7.0 9.7 1.1 9.2 4.3 2.2 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator VSP PF03302.13 EAY00279.1 - 0.00013 21.0 2.3 0.00013 21.0 2.3 2.0 2 0 0 2 2 2 1 Giardia variant-specific surface protein Orf78 PF06024.12 EAY00279.1 - 0.0026 18.0 0.0 0.0097 16.2 0.0 2.0 2 0 0 2 2 1 1 Orf78 (ac78) DUF3377 PF11857.8 EAY00279.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4690 PF15756.5 EAY00279.1 - 0.0073 16.9 0.1 0.035 14.7 0.1 2.2 1 0 0 1 1 1 1 Small Novel Rich in Cartilage ASFV_J13L PF05568.11 EAY00279.1 - 0.011 15.5 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Toxin-JAB1 PF15659.6 EAY00279.1 - 0.011 16.0 0.3 0.034 14.5 0.3 1.8 1 0 0 1 1 1 0 JAB-like toxin 1 Cloacin PF03515.14 EAY00279.1 - 0.034 13.8 0.7 0.52 9.9 0.1 2.5 2 0 0 2 2 2 0 Colicin-like bacteriocin tRNase domain DUF3149 PF11346.8 EAY00279.1 - 0.034 13.8 1.5 0.075 12.7 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Amnionless PF14828.6 EAY00279.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless YebO PF13974.6 EAY00279.1 - 0.07 13.2 1.0 0.18 11.9 1.0 1.7 1 0 0 1 1 1 0 YebO-like protein EphA2_TM PF14575.6 EAY00279.1 - 0.12 13.2 0.9 0.34 11.8 0.9 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAY00279.1 - 0.19 11.6 2.1 0.51 10.3 2.1 1.7 1 0 0 1 1 1 0 Syndecan domain CCSMST1 PF15013.6 EAY00279.1 - 0.2 11.9 0.5 0.49 10.6 0.5 1.6 1 0 0 1 1 1 0 CCSMST1 family DUF5385 PF17359.2 EAY00279.1 - 0.25 10.9 3.4 0.09 12.3 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 EAY00279.1 - 0.52 10.4 3.4 1.2 9.3 3.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LPD39 PF18858.1 EAY00280.1 - 0.1 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 RibD_C PF01872.17 EAY00281.1 - 1.7e-10 41.1 0.0 2.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF563 PF04577.14 EAY00282.1 - 1.7e-22 80.6 0.2 3.9e-22 79.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Pkinase PF00069.25 EAY00283.1 - 2.4e-69 233.6 0.0 3e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00283.1 - 1.2e-35 123.1 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAY00283.1 - 1.5e-17 64.0 0.5 3.6e-17 62.8 0.1 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 EAY00283.1 - 1.2e-07 32.3 0.1 2.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.6 EAY00283.1 - 7.6e-05 23.1 0.6 0.012 16.0 0.3 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.6 EAY00283.1 - 0.00061 19.2 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAY00283.1 - 0.0095 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 EAY00283.1 - 0.021 15.1 0.0 0.072 13.4 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 EAY00283.1 - 0.062 13.2 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EAY00283.1 - 0.11 12.0 0.1 6.1 6.4 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 EAY00284.1 - 5.3e-11 42.9 0.3 6.1e-11 42.8 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00284.1 - 2e-09 37.8 0.1 2.9e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY00284.1 - 2.8e-08 33.8 0.6 4.7e-05 23.6 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAY00284.1 - 2.4e-07 30.5 0.9 0.00068 19.9 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAY00284.1 - 6.2e-06 26.4 0.1 9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BCS1_N PF08740.11 EAY00284.1 - 0.045 13.7 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 BCS1 N terminal Ank_2 PF12796.7 EAY00285.1 - 6.1e-32 110.1 16.6 5e-14 52.6 1.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00285.1 - 4.2e-27 94.2 3.7 1.6e-10 41.3 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00285.1 - 5.5e-23 80.3 1.4 1.6e-07 31.4 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAY00285.1 - 6.3e-19 67.8 1.5 3e-10 40.1 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00285.1 - 1.4e-17 61.9 0.5 3.1e-05 24.0 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 EAY00285.1 - 0.086 12.8 1.1 3 7.9 0.2 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF3447) HSP70 PF00012.20 EAY00286.1 - 3.4e-23 81.7 0.1 8.5e-23 80.4 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein PhoD_N PF16655.5 EAY00286.1 - 0.019 15.5 0.0 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Ras PF00071.22 EAY00287.1 - 2.1e-25 89.2 0.2 2.4e-25 89.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY00287.1 - 3e-17 63.0 0.0 4.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY00287.1 - 7.4e-16 58.1 0.0 1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY00287.1 - 1.7e-12 47.2 0.1 2.2e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAY00287.1 - 2e-06 27.8 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAY00287.1 - 2.1e-05 24.2 0.2 0.0026 17.4 0.0 2.4 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EAY00287.1 - 2.6e-05 23.5 0.9 0.0091 15.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit PduV-EutP PF10662.9 EAY00287.1 - 0.00011 22.0 0.1 0.26 11.0 0.1 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EAY00287.1 - 0.00019 21.4 0.1 0.079 12.9 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAY00287.1 - 0.0016 17.9 0.0 0.0042 16.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EAY00287.1 - 0.0019 18.5 0.2 0.25 11.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 EAY00287.1 - 0.0044 17.1 0.1 0.019 15.1 0.1 2.0 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EAY00287.1 - 0.0067 16.0 0.1 2.5 7.6 0.0 2.3 2 1 0 2 2 2 2 Ferrous iron transport protein B Lipase_GDSL_3 PF14606.6 EAY00287.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AAA_15 PF13175.6 EAY00287.1 - 2 8.0 5.2 2 8.1 0.3 2.0 1 1 0 2 2 2 0 AAA ATPase domain Ank_4 PF13637.6 EAY00288.1 - 1.5e-47 159.4 12.1 6.5e-12 45.7 0.1 9.4 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00288.1 - 8.1e-47 157.7 21.4 8.3e-16 58.4 1.6 5.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00288.1 - 1.6e-44 148.4 12.8 3.2e-08 33.7 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat DUF3447 PF11929.8 EAY00288.1 - 1.6e-36 124.1 8.5 1.6e-36 124.1 8.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY00288.1 - 5.2e-35 115.5 13.1 5.5e-06 26.3 0.1 9.7 9 1 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAY00288.1 - 1.2e-27 95.5 9.5 4.1e-09 36.5 0.2 6.6 4 2 3 7 7 7 4 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 EAY00290.1 - 0.00037 20.8 2.9 0.00088 19.6 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type Dzip-like_N PF13815.6 EAY00290.1 - 0.0012 18.8 1.0 0.0012 18.8 1.0 2.3 2 1 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 EAY00290.1 - 0.0031 18.2 2.7 0.0071 17.1 2.7 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-MYST PF17772.1 EAY00290.1 - 0.0054 16.3 0.5 0.012 15.2 0.5 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain zf-Di19 PF05605.12 EAY00290.1 - 0.031 14.6 0.5 0.064 13.6 0.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TBD PF12845.7 EAY00290.1 - 0.12 12.3 2.5 0.16 11.9 0.5 2.2 2 0 0 2 2 2 0 TBD domain zf-H2C2_2 PF13465.6 EAY00290.1 - 0.42 11.1 4.2 0.18 12.3 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger double domain TolA_bind_tri PF16331.5 EAY00290.1 - 2 8.6 8.8 5.9 7.0 0.3 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation bZIP_1 PF00170.21 EAY00290.1 - 5.6 7.1 10.6 0.1 12.7 2.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor WAPL PF07814.13 EAY00292.1 - 0.0011 17.8 1.4 0.0069 15.2 0.6 2.3 2 1 1 3 3 3 1 Wings apart-like protein regulation of heterochromatin Pox_RNA_pol PF03293.14 EAY00292.1 - 0.0022 17.7 0.7 0.0046 16.7 0.7 1.5 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Arm PF00514.23 EAY00292.1 - 0.011 15.8 0.1 17 5.6 0.0 4.0 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat DUF832 PF05734.11 EAY00292.1 - 0.06 12.8 4.3 0.084 12.3 0.2 2.8 3 0 0 3 3 3 0 Herpesvirus protein of unknown function (DUF832) Ras PF00071.22 EAY00293.1 - 2.7e-46 157.2 0.1 3.4e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY00293.1 - 8e-29 100.3 0.1 1.5e-28 99.4 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY00293.1 - 2.8e-14 52.9 0.1 3.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY00293.1 - 4.2e-06 26.8 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAY00293.1 - 9.5e-05 21.9 0.1 0.00062 19.3 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAY00293.1 - 0.0023 17.7 0.4 0.051 13.3 0.4 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAY00293.1 - 0.026 14.1 0.1 1.3 8.6 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAY00293.1 - 0.04 13.4 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAY00293.1 - 0.049 13.5 0.0 5.8 6.8 0.0 2.4 1 1 2 3 3 3 0 RsgA GTPase MOZART1 PF12554.8 EAY00294.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated ADK PF00406.22 EAY00295.1 - 7.7e-41 139.7 0.0 9.6e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAY00295.1 - 3.5e-26 92.2 0.0 5.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAY00295.1 - 7.9e-11 42.6 0.0 1.4e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAY00295.1 - 0.0003 20.7 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.17 EAY00295.1 - 0.0016 18.2 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 EAY00295.1 - 0.0026 17.9 0.0 0.0048 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EAY00295.1 - 0.0049 17.0 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.6 EAY00295.1 - 0.0049 17.1 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EAY00295.1 - 0.029 14.3 0.8 0.08 12.8 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA PF00004.29 EAY00295.1 - 0.046 14.1 0.4 0.14 12.6 0.4 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 EAY00295.1 - 0.063 13.4 0.3 8.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 EAY00295.1 - 0.089 12.7 0.1 0.18 11.7 0.0 1.6 2 1 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 EAY00295.1 - 0.095 12.4 0.1 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 EAY00295.1 - 0.11 12.8 0.7 0.16 12.3 0.7 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAY00295.1 - 0.16 11.2 0.4 0.32 10.3 0.3 1.9 1 1 0 1 1 1 0 Zeta toxin IBD PF10416.9 EAY00296.1 - 2.5e-38 131.0 0.3 4.3e-38 130.2 0.3 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD MscS_porin PF12795.7 EAY00296.1 - 0.095 12.2 1.8 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TcdB_N PF12918.7 EAY00296.1 - 3.1 8.1 14.2 7.5 6.9 0.7 3.3 3 1 0 3 3 3 0 TcdB toxin N-terminal helical domain S1-P1_nuclease PF02265.16 EAY00297.1 - 4e-42 144.8 0.1 4.6e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Ank_5 PF13857.6 EAY00298.1 - 0.0017 18.7 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00298.1 - 0.0024 18.4 0.0 0.0039 17.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00298.1 - 0.0098 16.5 0.0 0.032 14.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY00298.1 - 0.02 15.4 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 EAY00298.1 - 0.057 14.0 0.0 0.087 13.4 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat hNIFK_binding PF12196.8 EAY00299.1 - 0.32 10.5 1.9 0.72 9.4 1.9 1.6 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Ank_2 PF12796.7 EAY00300.1 - 9.9e-41 138.2 7.4 2e-17 63.5 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00300.1 - 4.9e-24 84.4 0.0 1.7e-09 38.0 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00300.1 - 1e-21 76.7 0.1 1e-06 28.9 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00300.1 - 2e-17 61.5 0.1 0.0078 16.6 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EAY00300.1 - 1.7e-15 56.7 0.2 0.0093 16.4 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Adenine_glyco PF03352.13 EAY00300.1 - 0.088 12.6 3.6 0.12 12.1 2.9 1.6 1 1 0 1 1 1 0 Methyladenine glycosylase MRPL52 PF18699.1 EAY00300.1 - 0.13 12.5 3.8 0.11 12.6 1.6 2.0 2 0 0 2 2 2 0 Mitoribosomal protein mL52 LMBR1 PF04791.16 EAY00300.1 - 1.1 8.0 7.3 1.5 7.6 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RecG_N PF17190.4 EAY00300.1 - 3.5 8.4 11.8 0.14 12.9 3.7 2.8 2 2 1 3 3 3 0 RecG N-terminal helical domain DivIC PF04977.15 EAY00300.1 - 5.7 6.8 10.6 3.1 7.6 7.1 2.5 2 1 0 2 2 2 0 Septum formation initiator Sel1 PF08238.12 EAY00301.1 - 3.9e-12 46.4 11.5 0.015 16.0 0.0 5.4 5 0 0 5 5 5 4 Sel1 repeat DUF3270 PF11674.8 EAY00302.1 - 0.52 10.5 0.0 0.52 10.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3270) IF4E PF01652.18 EAY00303.1 - 1.9e-21 76.5 0.0 2.1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1376 PF07120.11 EAY00304.1 - 0.095 13.0 0.1 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) Clathrin PF00637.20 EAY00305.1 - 3.8e-06 26.8 0.7 3.8e-06 26.8 0.7 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_11 PF17123.5 EAY00305.1 - 0.0052 16.5 0.2 0.018 14.8 0.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EAY00305.1 - 0.011 16.0 4.6 0.037 14.4 4.6 2.0 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.32 EAY00305.1 - 0.036 14.9 0.1 0.15 12.9 0.1 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 EAY00305.1 - 0.059 13.4 2.7 0.16 12.0 2.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Mcl1_mid PF12341.8 EAY00305.1 - 0.089 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region zf-RING_5 PF14634.6 EAY00305.1 - 0.62 10.1 5.9 0.73 9.8 4.6 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Pkinase PF00069.25 EAY00307.1 - 3.9e-60 203.4 0.0 5.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00307.1 - 1.6e-38 132.5 0.0 2e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 EAY00307.1 - 7.9e-12 45.2 1.0 2.2e-11 43.8 0.2 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EAY00307.1 - 8.5e-10 38.4 0.0 3.2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAY00307.1 - 1e-07 31.1 0.0 1.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EAY00307.1 - 0.003 16.6 0.1 0.0051 15.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY00307.1 - 0.0033 16.8 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3127 PF11325.8 EAY00307.1 - 0.019 15.2 0.3 0.045 14.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) PH_15 PF17339.2 EAY00307.1 - 0.082 12.8 3.3 0.079 12.9 1.2 2.0 2 0 0 2 2 2 0 PH domain APH PF01636.23 EAY00307.1 - 0.23 11.3 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EAY00308.1 - 8.4e-51 171.8 0.2 9.8e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY00308.1 - 3e-30 104.9 0.1 4.3e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY00308.1 - 1.7e-14 53.7 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY00308.1 - 1.7e-07 30.8 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAY00308.1 - 7.9e-07 28.7 0.1 2.5e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAY00308.1 - 2.7e-06 27.1 0.3 3.5e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAY00308.1 - 5.4e-06 26.0 0.0 1.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EAY00308.1 - 2.7e-05 24.2 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAY00308.1 - 2.8e-05 24.1 0.1 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EAY00308.1 - 0.0028 17.8 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 EAY00308.1 - 0.0045 16.2 0.1 0.47 9.6 0.1 2.6 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.29 EAY00308.1 - 0.0085 16.5 0.0 0.02 15.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAY00308.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1786 PF08735.10 EAY00308.1 - 0.029 13.7 0.2 0.051 12.8 0.1 1.5 1 1 1 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) ApoA-II PF04711.13 EAY00308.1 - 0.043 14.0 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) AAA_14 PF13173.6 EAY00308.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain CBP_GIL PF10995.8 EAY00308.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL TniB PF05621.11 EAY00308.1 - 0.18 11.2 0.1 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Ank_2 PF12796.7 EAY00309.1 - 1.8e-27 95.7 10.5 1.7e-16 60.6 1.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00309.1 - 1.5e-24 85.2 1.7 2.2e-06 27.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAY00309.1 - 2.3e-24 85.5 7.6 6.2e-09 36.2 0.1 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00309.1 - 7.2e-18 62.8 5.9 0.0009 19.5 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 EAY00309.1 - 1.3e-16 60.3 2.3 1.3e-16 60.3 2.3 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY00309.1 - 1.8e-13 50.4 1.3 0.0012 19.1 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 EAY00309.1 - 0.013 15.7 0.9 20 5.5 0.0 3.4 1 1 1 3 3 3 0 Ribosomal protein S6 PAZ_siRNAbind PF12212.8 EAY00309.1 - 0.077 12.8 3.3 33 4.3 0.1 4.1 1 1 4 5 5 5 0 PAZ domain RL PF17797.1 EAY00309.1 - 3.4 7.7 8.4 39 4.3 0.1 4.1 2 1 3 5 5 5 0 RL domain LRR_4 PF12799.7 EAY00310.1 - 1.1e-17 63.8 24.6 2.7e-07 30.8 4.6 4.3 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY00310.1 - 1.5e-12 47.4 2.6 2.7e-08 33.5 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAY00310.1 - 2.1e-08 33.8 18.7 0.00054 19.7 8.6 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 EAY00310.1 - 1.2 9.9 23.8 46 5.1 0.1 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EAY00310.1 - 2.2 8.5 19.9 2.7 8.2 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich repeat TadF PF16964.5 EAY00310.1 - 3.1 7.5 6.5 6.9 6.4 6.5 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F ApoLp-III PF07464.11 EAY00311.1 - 0.0094 16.1 6.0 0.015 15.4 6.1 1.4 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF3450 PF11932.8 EAY00311.1 - 0.026 13.8 3.7 0.044 13.1 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4523 PF15023.6 EAY00311.1 - 0.049 13.5 1.4 0.1 12.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) Bep_C_terminal PF17841.1 EAY00311.1 - 0.059 13.6 0.7 0.11 12.7 0.2 1.8 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Nup35_RRM_2 PF14605.6 EAY00311.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif U3snoRNP10 PF12397.8 EAY00312.1 - 0.014 15.7 8.8 0.015 15.7 0.1 4.7 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 10 Spherulin4 PF12138.8 EAY00312.1 - 0.074 12.7 1.2 0.17 11.5 0.4 2.0 3 0 0 3 3 3 0 Spherulation-specific family 4 Solute_trans_a PF03619.16 EAY00312.1 - 0.12 11.9 2.8 0.15 11.6 1.1 1.8 1 1 1 2 2 2 0 Organic solute transporter Ostalpha PP2C_C PF07830.13 EAY00312.1 - 0.23 11.9 1.0 2 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain TPR_2 PF07719.17 EAY00313.1 - 0.0023 17.9 0.0 1.1 9.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAY00313.1 - 0.012 16.2 0.1 0.94 10.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN6_N PF18055.1 EAY00313.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.3 2 1 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_8 PF13181.6 EAY00313.1 - 0.2 12.0 4.6 4.8 7.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat OmdA PF13376.6 EAY00313.1 - 0.21 11.6 4.3 2.6 8.1 1.2 3.3 3 1 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Maelstrom PF13017.6 EAY00313.1 - 0.27 10.8 3.0 0.27 10.9 0.7 1.9 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Nnf1 PF03980.14 EAY00313.1 - 3.7 8.0 11.5 2 8.8 5.2 2.7 2 1 1 3 3 3 0 Nnf1 PorA PF11271.8 EAY00314.1 - 0.0011 18.4 1.4 0.0012 18.2 1.4 1.0 1 0 0 1 1 1 1 Porin PorA HTH_DeoR PF08220.12 EAY00314.1 - 0.066 13.0 0.4 6 6.7 0.0 2.3 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain DEAD PF00270.29 EAY00315.1 - 3.4e-40 137.7 0.5 2.9e-39 134.6 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAY00315.1 - 5.7e-29 100.7 0.9 9.4e-28 96.8 0.3 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAY00315.1 - 1e-06 28.9 0.1 3.1e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAY00315.1 - 5.2e-05 22.7 0.1 0.00011 21.7 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 EAY00315.1 - 0.0097 16.3 1.4 0.12 12.8 0.6 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PTSIIA_gutA PF03829.13 EAY00315.1 - 0.019 14.8 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component AAA_30 PF13604.6 EAY00315.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4844 PF16133.5 EAY00315.1 - 0.056 14.0 3.9 0.11 13.1 0.9 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4844) tRNA-synt_1b PF00579.25 EAY00315.1 - 0.056 12.7 0.1 0.24 10.7 0.0 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (W and Y) THF_DHG_CYH_C PF02882.19 EAY00315.1 - 0.077 12.3 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NACHT PF05729.12 EAY00315.1 - 0.1 12.5 0.1 1.9 8.4 0.1 2.3 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EAY00315.1 - 0.11 12.7 2.9 1.6 9.0 1.1 2.9 1 1 1 2 2 2 0 AAA domain DUF3447 PF11929.8 EAY00316.1 - 5.6e-36 122.3 4.5 5.6e-36 122.3 4.5 3.3 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00316.1 - 3.5e-14 53.2 0.2 1.6e-09 38.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00316.1 - 4.3e-12 46.3 0.2 2.5e-07 31.1 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00316.1 - 2.9e-09 36.4 0.1 1e-05 25.5 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EAY00316.1 - 6.6e-08 32.7 0.0 2.5e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAY00316.1 - 1.6e-06 28.3 0.0 0.0042 17.4 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3023 PF11224.8 EAY00316.1 - 0.06 13.2 0.7 0.53 10.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) RL PF17797.1 EAY00316.1 - 0.16 12.0 6.5 0.29 11.1 0.4 3.5 4 0 0 4 4 4 0 RL domain TPR_19 PF14559.6 EAY00317.1 - 0.0064 17.0 0.2 0.24 11.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat Phage_holin_6_1 PF09682.10 EAY00317.1 - 0.0075 16.7 1.5 0.0075 16.7 1.5 1.8 2 0 0 2 2 2 1 Bacteriophage holin of superfamily 6 (Holin_LLH) SHR-BD PF06650.12 EAY00317.1 - 0.33 10.3 3.2 3.4 7.0 0.1 2.6 2 1 1 3 3 3 0 SHR-binding domain of vacuolar-sorting associated protein 13 CS PF04969.16 EAY00317.1 - 0.66 11.0 3.5 1.7 9.7 0.7 2.3 2 0 0 2 2 2 0 CS domain TPR_8 PF13181.6 EAY00317.1 - 6.7 7.2 9.5 9.5 6.7 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Chlam_PMP PF02415.17 EAY00318.1 - 0.23 12.0 3.4 95 3.8 0.0 4.6 3 1 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ank_2 PF12796.7 EAY00319.1 - 9.7e-38 128.6 0.0 4.3e-12 46.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00319.1 - 2.2e-31 107.8 0.0 1.2e-09 38.5 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00319.1 - 3.8e-26 88.3 0.0 0.011 16.2 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EAY00319.1 - 5.9e-24 83.4 0.0 0.0018 18.6 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAY00319.1 - 7.9e-24 83.4 0.0 0.00046 20.4 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) DUF3427 PF11907.8 EAY00319.1 - 0.0066 15.8 0.1 0.35 10.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3427) L_protein_N PF15518.6 EAY00319.1 - 0.025 14.4 0.0 4 7.4 0.0 3.6 1 1 0 1 1 1 0 L protein N-terminus NES_C_h PF18208.1 EAY00319.1 - 0.073 13.3 0.0 15 5.9 0.0 2.2 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain SRR PF07709.11 EAY00319.1 - 3.9 8.3 5.8 47 5.0 0.5 2.7 2 0 0 2 2 2 0 Seven Residue Repeat LRR_5 PF13306.6 EAY00320.1 - 6.5e-24 84.3 8.5 6.5e-24 84.3 8.5 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00320.1 - 4.1e-05 23.3 0.1 0.2 11.4 0.0 3.4 2 1 1 3 3 3 2 Leucine rich repeat Orf78 PF06024.12 EAY00320.1 - 0.002 18.4 0.1 0.0033 17.7 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF4448 PF14610.6 EAY00320.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 EAY00320.1 - 0.028 14.5 1.1 0.061 13.4 1.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_5 PF13306.6 EAY00321.1 - 1.3e-42 144.8 26.5 6.9e-22 77.8 8.3 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00321.1 - 3.5e-18 65.1 0.5 1.9e-06 27.5 0.0 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EAY00321.1 - 2.3e-05 24.6 9.8 0.092 13.2 0.3 4.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EAY00322.1 - 5.8e-144 469.1 10.9 1.9e-20 73.2 0.0 8.7 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00322.1 - 1.2e-94 309.6 0.0 2e-10 41.0 0.0 10.5 5 4 7 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00322.1 - 4.7e-92 300.9 0.0 4.1e-09 36.5 0.0 14.2 1 1 13 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 EAY00322.1 - 1.4e-83 271.9 0.0 0.00017 21.8 0.0 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.6 EAY00322.1 - 3.4e-70 223.6 0.0 0.0068 16.8 0.0 14.5 14 0 0 14 14 14 14 Ankyrin repeat Rad4 PF03835.15 EAY00322.1 - 0.00039 20.1 22.3 1.3 8.7 0.5 7.5 6 2 3 9 9 9 4 Rad4 transglutaminase-like domain GATase_7 PF13537.6 EAY00322.1 - 0.0036 17.2 0.0 92 3.0 0.0 6.0 7 0 0 7 7 7 0 Glutamine amidotransferase domain DUF3645 PF12359.8 EAY00322.1 - 0.0048 16.3 0.0 43 3.6 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3645) PA_decarbox PF05870.11 EAY00323.1 - 1.8e-86 287.6 0.3 2e-86 287.5 0.3 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.9 EAY00323.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 MoaF N-terminal domain MoaF_C PF17409.2 EAY00323.1 - 0.046 13.4 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 MoaF C-terminal domain Pkinase PF00069.25 EAY00324.1 - 8.4e-25 87.6 0.0 1.6e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00324.1 - 3.6e-19 69.0 0.0 8.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1400 PF07176.11 EAY00324.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.2 3 1 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) TFIIA PF03153.13 EAY00324.1 - 0.53 10.2 29.4 0.88 9.5 29.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_ISL3 PF01610.17 EAY00325.1 - 1.7e-05 24.7 0.2 4.5e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Transposase RRM_1 PF00076.22 EAY00326.1 - 4.9e-49 164.0 0.3 3.5e-16 58.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAY00326.1 - 2.2e-09 37.1 0.0 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EAY00326.1 - 2.5e-09 36.8 0.0 0.012 15.2 0.0 3.0 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAY00326.1 - 4.8e-09 36.2 0.1 0.014 15.4 0.0 3.8 3 1 0 3 3 3 3 Limkain b1 Nup35_RRM PF05172.13 EAY00326.1 - 1.6e-07 31.2 0.6 0.082 12.9 0.0 3.9 2 2 1 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAY00326.1 - 9e-07 28.9 0.0 0.00068 19.6 0.0 2.5 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 EAY00326.1 - 0.00013 21.8 0.0 8.4 6.3 0.0 3.2 3 0 0 3 3 3 3 Occluded RNA-recognition motif tRNA_anti-codon PF01336.25 EAY00326.1 - 0.084 12.9 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Guanylate_cyc PF00211.20 EAY00327.1 - 1.9e-43 148.2 0.1 4.8e-43 146.9 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY00327.1 - 1.6e-15 57.2 0.1 4.1e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EAY00327.1 - 1.2e-05 25.5 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAY00327.1 - 0.00017 21.5 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAY00327.1 - 0.0061 16.0 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated PAS_3 PF08447.12 EAY00327.1 - 0.023 14.9 0.0 0.091 13.1 0.0 2.0 2 0 0 2 2 2 0 PAS fold Mem_trans PF03547.18 EAY00328.1 - 6.8e-20 70.8 32.0 2.1e-16 59.3 10.4 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF4108 PF13390.6 EAY00330.1 - 9.6e-64 213.6 5.8 1.1e-63 213.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2362 PF10154.9 EAY00331.1 - 0.0015 17.6 2.6 0.0022 17.0 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) ChlamPMP_M PF07548.11 EAY00331.1 - 1.9 8.4 9.7 4.4 7.2 9.7 1.5 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Myb_DNA-binding PF00249.31 EAY00332.1 - 9.7e-28 96.1 1.6 3.4e-14 52.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00332.1 - 4.5e-18 65.2 5.0 4e-10 39.8 0.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY00332.1 - 6.5e-08 32.6 2.0 0.016 15.2 0.0 3.8 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY00332.1 - 0.00024 20.9 0.8 0.38 10.7 0.2 2.3 2 0 0 2 2 2 2 Myb DNA-binding like HSP70 PF00012.20 EAY00333.1 - 3e-81 273.4 10.8 5.4e-77 259.4 1.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAY00333.1 - 4.9e-12 45.3 0.1 5.5e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Glyco_hydro_47 PF01532.20 EAY00334.1 - 6.5e-128 427.5 0.4 8e-128 427.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 KilA-N PF04383.13 EAY00336.1 - 4.5e-31 107.0 0.4 1.1e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain Pox_A32 PF04665.12 EAY00337.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAY00337.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAY00337.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAY00337.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) Adeno_E3_CR2 PF02439.15 EAY00338.1 - 0.0043 16.8 1.1 0.01 15.6 1.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 VSP PF03302.13 EAY00338.1 - 0.005 15.8 2.1 0.0089 14.9 2.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein ASFV_J13L PF05568.11 EAY00338.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 EAY00338.1 - 0.0097 15.8 0.4 0.032 14.2 0.4 1.8 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 EAY00338.1 - 0.027 14.6 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 EAY00338.1 - 0.035 14.7 0.0 0.088 13.4 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2207 PF09972.9 EAY00341.1 - 0.00041 19.3 0.0 0.00043 19.2 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Syndecan PF01034.20 EAY00341.1 - 0.00043 20.1 0.6 0.00073 19.4 0.6 1.4 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 EAY00341.1 - 0.0013 18.7 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 EAY00341.1 - 0.0016 18.2 0.3 0.0016 18.2 0.3 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Orf78 PF06024.12 EAY00341.1 - 0.0021 18.3 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) EphA2_TM PF14575.6 EAY00341.1 - 0.0021 18.9 0.2 0.0042 17.9 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EAY00341.1 - 0.0021 17.8 0.5 0.005 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5385 PF17359.2 EAY00341.1 - 0.003 17.2 1.0 0.0041 16.7 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Protocadherin PF08374.11 EAY00341.1 - 0.014 15.4 0.2 0.018 15.0 0.2 1.2 1 0 0 1 1 1 0 Protocadherin DUF347 PF03988.12 EAY00341.1 - 0.015 15.4 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Baculo_11_kDa PF06143.11 EAY00341.1 - 0.019 14.5 0.8 0.034 13.7 0.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Amnionless PF14828.6 EAY00341.1 - 0.02 13.8 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF3827 PF12877.7 EAY00341.1 - 0.02 13.3 0.2 0.023 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ECSCR PF15820.5 EAY00341.1 - 0.023 14.5 0.3 0.039 13.8 0.3 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 EAY00341.1 - 0.026 14.6 3.1 0.049 13.7 3.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mid2 PF04478.12 EAY00341.1 - 0.028 14.3 1.1 0.038 13.8 1.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EAY00341.1 - 0.03 14.4 0.3 0.043 13.9 0.3 1.2 1 0 0 1 1 1 0 Podoplanin Otopetrin PF03189.13 EAY00341.1 - 0.031 13.1 0.1 0.034 13.0 0.1 1.1 1 0 0 1 1 1 0 Otopetrin DUF4199 PF13858.6 EAY00341.1 - 0.036 14.5 0.1 0.051 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) NfeD PF01957.18 EAY00341.1 - 0.042 14.2 0.1 12 6.3 0.0 2.8 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding O-ag_pol_Wzy PF14296.6 EAY00341.1 - 0.061 12.0 4.2 0.33 9.5 0.0 2.0 1 1 1 2 2 2 0 O-antigen polysaccharide polymerase Wzy EVC2_like PF12297.8 EAY00341.1 - 0.25 10.0 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein LRR_5 PF13306.6 EAY00343.1 - 1e-124 410.2 46.2 2.1e-36 124.7 2.6 5.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00343.1 - 5.3e-18 64.5 0.2 0.0064 16.2 0.0 7.4 3 3 6 9 9 9 5 Leucine rich repeat A2M PF00207.22 EAY00343.1 - 0.0065 16.3 0.0 1 9.2 0.0 3.7 3 0 0 3 3 3 1 Alpha-2-macroglobulin family PTR PF12789.7 EAY00344.1 - 1.1e-49 166.3 35.2 1.2e-32 111.8 17.2 5.1 5 1 1 6 6 6 2 Phage tail repeat like DUF1493 PF07377.12 EAY00345.1 - 0.03 14.8 0.9 0.063 13.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Flavodoxin_2 PF02525.17 EAY00346.1 - 9.6e-31 107.0 0.0 1.2e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold U3snoRNP10 PF12397.8 EAY00347.1 - 0.067 13.6 3.9 0.32 11.4 0.0 3.4 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Ank_4 PF13637.6 EAY00348.1 - 3.5e-49 164.5 20.3 1.8e-09 38.0 0.1 10.0 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00348.1 - 1.8e-48 163.0 41.5 1.9e-12 47.6 1.3 6.7 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00348.1 - 2.9e-44 147.6 16.0 1e-08 35.3 0.0 9.6 9 1 0 9 9 9 7 Ankyrin repeat DUF3447 PF11929.8 EAY00348.1 - 5.9e-36 122.3 4.4 5.9e-36 122.3 4.4 4.1 4 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY00348.1 - 2.1e-35 116.7 19.3 5.7e-07 29.4 0.0 11.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 EAY00348.1 - 2.9e-32 110.3 11.0 3.7e-11 43.0 0.1 6.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) CdhD PF03599.16 EAY00348.1 - 0.0056 15.4 0.2 0.051 12.3 0.0 2.4 3 0 0 3 3 3 1 CO dehydrogenase/acetyl-CoA synthase delta subunit RL PF17797.1 EAY00348.1 - 0.3 11.0 11.8 21 5.1 0.0 6.2 4 2 4 8 8 8 0 RL domain DUF4147 PF13660.6 EAY00348.1 - 9.3 5.7 6.6 71 2.8 0.0 4.4 5 1 0 6 6 6 0 Domain of unknown function (DUF4147) IBD PF10416.9 EAY00349.1 - 2.2e-43 147.3 1.1 3.8e-43 146.6 1.1 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PI_PP_I PF18363.1 EAY00349.1 - 0.019 15.2 1.0 3.1 8.0 0.1 3.3 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain eIF-3c_N PF05470.12 EAY00349.1 - 0.034 12.5 0.1 0.044 12.1 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Aldose_epim PF01263.20 EAY00350.1 - 7.1e-23 81.4 1.1 9.7e-23 80.9 1.1 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_38C PF07748.13 EAY00350.1 - 8e-05 22.8 0.2 0.00011 22.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain B3 PF02362.21 EAY00350.1 - 0.051 13.4 0.5 0.14 12.0 0.5 1.7 1 0 0 1 1 1 0 B3 DNA binding domain Ank_2 PF12796.7 EAY00351.1 - 8.3e-136 442.9 101.9 8.5e-15 55.1 2.0 10.6 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00351.1 - 3.9e-135 438.6 42.2 8.1e-11 42.2 0.4 15.9 1 1 14 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 EAY00351.1 - 1.2e-132 427.1 45.2 4.7e-08 33.1 0.4 16.0 16 0 0 16 16 16 16 Ankyrin repeat Ank_3 PF13606.6 EAY00351.1 - 1.9e-96 304.3 45.8 2.8e-05 24.2 0.1 16.1 16 0 0 16 16 16 16 Ankyrin repeat Ank_5 PF13857.6 EAY00351.1 - 7.6e-84 274.7 40.5 3.8e-10 39.8 1.2 9.2 4 3 1 9 9 9 9 Ankyrin repeats (many copies) YcxB PF14317.6 EAY00351.1 - 0.00014 21.5 2.1 96 2.8 0.0 7.9 8 2 2 10 10 10 0 YcxB-like protein KdgM PF06178.13 EAY00351.1 - 0.00018 21.2 8.2 15 5.1 0.1 6.2 3 2 6 9 9 9 2 Oligogalacturonate-specific porin protein (KdgM) CDC37_M PF08565.11 EAY00351.1 - 0.00023 21.1 27.5 3.3 7.7 0.1 9.3 4 2 8 12 12 12 4 Cdc37 Hsp90 binding domain LisH PF08513.11 EAY00351.1 - 0.0014 18.5 1.0 1e+02 3.1 0.0 6.6 5 0 0 5 5 5 0 LisH DHBP_synthase PF00926.19 EAY00351.1 - 0.11 12.1 14.8 16 4.9 0.0 8.7 1 1 9 12 12 12 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Hormone_3 PF00159.18 EAY00351.1 - 7.8 6.7 10.1 5.3e+02 0.8 0.0 6.2 8 0 0 8 8 8 0 Pancreatic hormone peptide Ank_2 PF12796.7 EAY00352.1 - 6.9e-160 520.1 140.4 7.2e-15 55.3 3.5 13.1 2 2 15 17 17 17 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00352.1 - 7.2e-154 498.4 63.3 1.3e-09 38.4 0.0 21.2 3 1 18 21 21 21 19 Ankyrin repeats (many copies) Ank PF00023.30 EAY00352.1 - 2.6e-143 460.8 61.7 8.7e-08 32.3 0.4 20.6 21 0 0 21 21 21 19 Ankyrin repeat Ank_3 PF13606.6 EAY00352.1 - 1.8e-97 307.4 60.5 3.7e-05 23.8 0.2 21.8 22 0 0 22 22 22 19 Ankyrin repeat Ank_5 PF13857.6 EAY00352.1 - 3.7e-90 294.8 53.5 8.7e-10 38.7 0.2 12.2 5 2 3 12 12 12 11 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00352.1 - 2.5e-38 129.9 5.7 2.5e-38 129.9 5.7 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) YcxB PF14317.6 EAY00352.1 - 6e-06 25.9 0.2 54 3.6 0.0 9.5 7 2 4 11 11 11 0 YcxB-like protein KdgM PF06178.13 EAY00352.1 - 0.00012 21.8 13.6 8.8 5.9 0.1 6.7 3 2 4 7 7 7 3 Oligogalacturonate-specific porin protein (KdgM) CDC37_M PF08565.11 EAY00352.1 - 0.002 18.0 24.7 6 6.8 0.1 9.4 4 3 7 11 11 11 2 Cdc37 Hsp90 binding domain INCENP_ARK-bind PF03941.15 EAY00352.1 - 0.33 10.9 4.0 31 4.6 0.0 4.8 3 2 4 7 7 7 0 Inner centromere protein, ARK binding region DHBP_synthase PF00926.19 EAY00352.1 - 2.8 7.4 13.7 37 3.8 0.1 8.0 3 3 9 12 12 12 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Flavodoxin_2 PF02525.17 EAY00354.1 - 7.1e-35 120.5 0.1 8.4e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAY00354.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Spo0A_C PF08769.11 EAY00355.1 - 0.063 13.4 0.3 0.15 12.1 0.2 1.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal GPS2_interact PF15784.5 EAY00357.1 - 0.041 14.3 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY00357.1 - 0.075 12.0 0.1 0.07 12.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PDEase_I PF00233.19 EAY00362.1 - 7.7e-78 261.5 1.4 1.4e-77 260.7 1.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EAY00362.1 - 2e-24 86.7 0.0 9.5e-12 45.7 0.0 4.5 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 EAY00362.1 - 4.3e-18 65.9 0.0 1.3e-05 25.6 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 EAY00362.1 - 2.8e-12 47.1 0.0 6.5e-05 23.3 0.0 4.0 4 0 0 4 4 4 3 GAF domain DUF3369 PF11849.8 EAY00362.1 - 2.2e-05 24.8 1.4 2.1 8.5 0.0 4.3 3 1 0 4 4 4 2 Domain of unknown function (DUF3369) HD PF01966.22 EAY00362.1 - 0.2 11.8 0.0 0.54 10.5 0.0 1.7 1 0 0 1 1 1 0 HD domain DKCLD PF08068.12 EAY00364.1 - 2.2e-30 104.5 0.1 3.8e-29 100.5 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EAY00364.1 - 1.7e-22 80.4 3.0 8.1e-14 52.2 0.0 4.0 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EAY00364.1 - 6.1e-20 71.1 0.2 1.3e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EAY00364.1 - 1.4e-16 60.1 0.8 3.1e-16 59.1 0.8 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EAY00364.1 - 0.0069 16.6 0.1 0.18 12.1 0.0 2.9 3 0 0 3 3 3 1 UPF0113 PUA domain Tex_YqgF PF16921.5 EAY00364.1 - 0.069 13.6 0.3 0.15 12.5 0.3 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain Alba PF01918.21 EAY00364.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Alba Cnd1 PF12717.7 EAY00365.1 - 0.022 14.8 7.3 0.5 10.4 0.6 3.8 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.6 EAY00365.1 - 0.022 15.1 5.6 11 6.3 0.5 3.6 2 2 0 2 2 2 0 FANCI solenoid 2 UNC45-central PF11701.8 EAY00365.1 - 0.061 13.3 6.0 0.097 12.6 1.1 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 EAY00365.1 - 0.062 13.7 0.0 0.46 10.9 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats TIP120 PF08623.10 EAY00365.1 - 0.4 10.4 2.2 1.9 8.2 0.2 2.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) P16-Arc PF04699.14 EAY00366.1 - 1.8e-16 60.9 0.4 1.3e-15 58.2 0.4 1.9 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) NUDIX PF00293.28 EAY00367.1 - 2.2e-12 47.2 0.0 3.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 EAY00367.1 - 0.0026 18.0 8.4 0.0028 17.9 4.1 2.8 2 1 0 2 2 2 1 Dcp2, box A domain NAD_binding_5 PF07994.12 EAY00368.1 - 1.4e-139 465.0 0.0 1.6e-139 464.8 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EAY00368.1 - 1.2e-42 144.6 0.1 2e-42 143.8 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FUR PF01475.19 EAY00368.1 - 0.0018 18.4 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 Ferric uptake regulator family Ribonuc_L-PSP PF01042.21 EAY00370.1 - 0.68 10.0 3.6 1.3 9.0 0.0 2.9 3 1 0 3 3 3 0 Endoribonuclease L-PSP TTL PF03133.15 EAY00371.1 - 2.4e-59 200.9 0.1 4e-59 200.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAY00371.1 - 6.5e-09 35.4 0.7 0.053 12.8 0.0 3.5 3 1 1 4 4 4 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAY00371.1 - 0.0011 18.2 0.0 0.23 10.7 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EAY00371.1 - 0.0019 18.3 0.1 0.046 13.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EAY00371.1 - 0.0066 16.1 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EAY00371.1 - 0.071 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain HEAT PF02985.22 EAY00373.1 - 0.0017 18.4 0.7 7.3 7.2 0.0 4.1 3 1 1 4 4 4 2 HEAT repeat V-ATPase_H_C PF11698.8 EAY00373.1 - 0.034 14.3 2.1 0.29 11.2 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H Thioredoxin PF00085.20 EAY00374.1 - 7.7e-19 67.6 0.1 1.4e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAY00374.1 - 0.0047 17.2 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EAY00374.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Ribosomal_L16 PF00252.18 EAY00375.1 - 2.7e-32 111.5 0.2 3.3e-32 111.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 EAY00375.1 - 0.016 15.2 0.2 9 6.5 0.0 2.9 3 0 0 3 3 3 0 Corticotropin-releasing factor family CAP_N PF01213.19 EAY00376.1 - 4.4e-42 144.7 0.2 6.7e-42 144.1 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EAY00376.1 - 4.4e-35 120.6 3.6 7.5e-35 119.9 3.6 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EAY00376.1 - 0.00017 21.3 0.6 0.00033 20.4 0.6 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Ribosomal_60s PF00428.19 EAY00376.1 - 1.4 9.6 17.0 0.14 12.8 8.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RCC1 PF00415.18 EAY00377.1 - 3.3e-26 91.7 18.5 4e-09 37.0 0.4 8.6 7 2 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAY00377.1 - 8.9e-21 73.2 15.3 2.4e-05 24.0 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 EAY00378.1 - 2.2e-07 30.6 0.1 5.5e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAY00378.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CK_II_beta PF01214.18 EAY00379.1 - 1.1e-50 172.0 0.8 1.3e-50 171.8 0.8 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4490 PF14892.6 EAY00380.1 - 7.3e-10 38.8 0.4 8.1e-10 38.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Got1 PF04178.12 EAY00381.1 - 7.7e-23 81.1 18.0 9.9e-23 80.7 18.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 EAY00381.1 - 0.057 13.7 0.1 0.057 13.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4064 PF13273.6 EAY00381.1 - 1.1 9.5 16.4 0.058 13.7 3.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Acetyltransf_16 PF05301.11 EAY00383.1 - 1.4e-57 194.2 0.1 1.8e-57 193.9 0.1 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 EAY00383.1 - 0.00085 19.7 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAY00383.1 - 0.0051 17.0 0.0 0.0085 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAY00383.1 - 0.071 13.1 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lactamase_B_2 PF12706.7 EAY00384.1 - 2.1e-29 102.5 0.0 2.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAY00384.1 - 3e-15 56.5 0.0 7.8e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAY00384.1 - 0.011 15.8 2.9 0.37 10.8 3.2 2.4 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Myb_DNA-binding PF00249.31 EAY00385.1 - 4.6e-33 113.2 5.2 1.2e-17 63.8 0.9 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00385.1 - 5.5e-30 103.4 6.7 4.9e-20 71.5 0.6 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY00385.1 - 8.4e-10 38.4 0.6 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAY00385.1 - 1.1e-07 31.9 0.8 0.0018 18.3 0.0 2.5 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAY00385.1 - 6.3e-07 29.4 0.8 0.014 15.5 0.1 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EAY00385.1 - 1.8e-06 28.1 2.0 0.00043 20.4 0.3 2.4 2 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAY00385.1 - 0.071 13.5 9.8 1.5 9.2 0.9 4.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUP PF00674.18 EAY00385.1 - 0.16 12.1 0.7 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 DUP family Myb_DNA-bind_5 PF13873.6 EAY00385.1 - 0.53 10.4 5.5 6 7.0 0.0 3.5 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pneumo_matrix PF03393.16 EAY00387.1 - 0.034 13.4 0.3 0.045 13.0 0.3 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein FAM76 PF16046.5 EAY00387.1 - 0.035 13.5 1.4 0.039 13.3 1.4 1.0 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 EAY00387.1 - 0.13 11.5 6.6 0.023 13.9 2.9 1.6 1 1 1 2 2 2 0 TMPIT-like protein RicinB_lectin_2 PF14200.6 EAY00388.1 - 4e-13 49.9 0.8 3.2e-08 34.2 0.2 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAY00388.1 - 2e-10 41.0 0.2 2.6e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DENN PF02141.21 EAY00389.1 - 0.036 14.0 0.3 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain Proteasome PF00227.26 EAY00390.1 - 5e-24 84.8 0.1 5.6e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FtsJ PF01728.19 EAY00392.1 - 1.7e-54 184.6 0.0 2e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EAY00392.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F TPR_2 PF07719.17 EAY00393.1 - 1e-13 50.2 5.7 0.19 11.9 0.1 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAY00393.1 - 2.4e-13 49.3 8.5 0.0088 15.8 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAY00393.1 - 8.5e-10 38.2 0.7 0.17 11.6 0.0 5.2 4 1 0 4 4 4 3 TPR repeat TPR_9 PF13371.6 EAY00393.1 - 4.4e-09 36.4 0.0 0.036 14.2 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAY00393.1 - 3.8e-06 27.3 1.0 11 6.6 0.1 5.4 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAY00393.1 - 2e-05 25.0 0.0 0.15 12.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAY00393.1 - 0.0002 21.5 4.1 0.014 15.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAY00393.1 - 0.00041 20.9 0.3 16 6.2 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EAY00393.1 - 0.0046 17.3 0.0 3.8 7.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4278 PF14105.6 EAY00393.1 - 0.16 12.4 0.1 0.54 10.7 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4278) ANAPC3 PF12895.7 EAY00393.1 - 0.23 11.7 15.2 1.3 9.3 1.0 4.8 3 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NT-C2 PF10358.9 EAY00394.1 - 2.7e-25 88.8 2.9 4.9e-25 88.0 2.9 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L16 PF00252.18 EAY00395.1 - 4.1e-33 114.2 0.0 5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 EAY00395.1 - 0.058 13.5 0.2 9 6.5 0.0 2.9 3 0 0 3 3 3 0 Corticotropin-releasing factor family Beach PF02138.18 EAY00396.1 - 5.9e-17 61.9 4.5 3.5e-09 36.4 0.1 3.1 3 0 0 3 3 3 2 Beige/BEACH domain DUF3755 PF12579.8 EAY00396.1 - 0.024 14.3 0.1 0.13 11.9 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) BACK PF07707.15 EAY00397.1 - 0.0097 16.0 0.4 0.025 14.7 0.4 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch RibD_C PF01872.17 EAY00398.1 - 3.7e-16 59.6 0.0 4.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Guanylate_cyc PF00211.20 EAY00399.1 - 2e-45 154.6 0.0 4.1e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY00399.1 - 1.2e-10 41.6 0.1 3.1e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAY00399.1 - 1.2e-05 25.3 0.0 4.7e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EAY00399.1 - 7.1e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAY00399.1 - 0.02 14.3 0.1 0.049 13.1 0.1 1.7 1 0 0 1 1 1 0 Heme NO binding associated PAS_8 PF13188.7 EAY00399.1 - 0.06 13.4 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 PAS domain TMEMspv1-c74-12 PF11044.8 EAY00399.1 - 4.4 7.4 7.2 29 4.7 5.5 3.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein IFT20 PF14931.6 EAY00400.1 - 6.7 6.9 9.7 1.6 8.9 0.6 2.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Phage_sheath_1C PF17482.2 EAY00404.1 - 0.062 13.3 0.4 1.1 9.2 0.1 2.7 1 1 2 3 3 3 0 Phage tail sheath C-terminal domain HTH_Crp_2 PF13545.6 EAY00404.1 - 0.17 11.9 0.1 2 8.4 0.1 2.5 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HEAT PF02985.22 EAY00405.1 - 0.053 13.8 0.0 0.22 11.9 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 EAY00405.1 - 0.055 13.9 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats LRR_6 PF13516.6 EAY00405.1 - 0.063 13.4 0.1 0.063 13.4 0.1 4.1 5 0 0 5 5 5 0 Leucine Rich repeat Cnd1 PF12717.7 EAY00405.1 - 0.07 13.2 12.1 0.065 13.3 0.9 4.8 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RecG_N PF17190.4 EAY00405.1 - 0.34 11.7 10.0 11 6.9 0.2 5.6 4 1 1 5 5 5 0 RecG N-terminal helical domain LRR_4 PF12799.7 EAY00405.1 - 5 7.7 23.3 10 6.7 4.8 6.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) DUF3839 PF12943.7 EAY00406.1 - 1.6e-156 518.9 12.2 2.1e-156 518.5 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY00406.1 - 0.098 12.5 0.8 0.31 10.9 0.8 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAY00406.1 - 1 9.9 5.6 2.1 8.9 0.7 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2408 PF10303.9 EAY00406.1 - 3.2 8.3 6.1 1.3 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Ank_2 PF12796.7 EAY00408.1 - 6.5e-05 23.4 0.1 0.022 15.3 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY00408.1 - 0.0013 18.7 1.4 0.0013 18.7 1.4 3.0 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY00408.1 - 0.0098 16.3 0.0 30 5.7 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat PSP PF04046.16 EAY00409.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP KilA-N PF04383.13 EAY00411.1 - 1.1e-41 141.2 0.5 2.2e-41 140.2 0.1 1.7 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAY00411.1 - 0.011 16.4 0.1 0.03 15.0 0.0 1.8 2 0 0 2 2 2 0 Parathyroid hormone family Pox_A32 PF04665.12 EAY00412.1 - 5.1e-07 29.4 1.4 5.1e-07 29.4 1.4 2.0 2 2 1 3 3 3 1 Poxvirus A32 protein IstB_IS21 PF01695.17 EAY00412.1 - 2.1e-05 24.3 0.4 0.18 11.5 0.0 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EAY00412.1 - 4.9e-05 23.6 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAY00412.1 - 5.3e-05 23.3 4.3 0.00011 22.2 3.9 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00412.1 - 0.00041 20.2 0.0 0.00074 19.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00412.1 - 0.0019 18.0 1.2 0.0047 16.7 0.6 1.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00412.1 - 0.0043 16.7 2.0 0.014 15.0 0.2 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) SWI2_SNF2 PF18766.1 EAY00412.1 - 0.013 15.2 0.7 0.026 14.2 0.3 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 EAY00412.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00412.1 - 0.053 13.9 0.0 0.46 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAY00412.1 - 0.079 12.5 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAY00412.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY00412.1 - 0.57 10.5 4.3 10 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF573 PF04504.14 EAY00412.1 - 1.3 9.8 12.1 0.43 11.3 1.6 3.6 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF1772 PF08592.11 EAY00414.1 - 0.067 13.5 0.4 0.87 9.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF3159 PF11361.8 EAY00414.1 - 0.39 10.4 2.5 0.72 9.6 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Herpes_LMP1 PF05297.11 EAY00414.1 - 2.5 7.2 10.0 4.1 6.5 10.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Gly_rich PF12810.7 EAY00416.1 - 1.9e-55 188.5 33.6 2.2e-55 188.2 33.6 1.0 1 0 0 1 1 1 1 Glycine rich protein TPR_MLP1_2 PF07926.12 EAY00417.1 - 0.037 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY00417.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY00417.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAY00418.1 - 3.5e-72 241.0 11.8 3.9e-72 240.8 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Thioredoxin_6 PF13848.6 EAY00419.1 - 1.2e-09 38.3 5.8 1.3e-07 31.8 1.2 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 EAY00419.1 - 2.1e-06 27.7 0.0 9.3e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EAY00419.1 - 0.0047 17.2 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAY00419.1 - 0.037 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EAY00419.1 - 0.076 13.5 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2935 PF11155.8 EAY00420.1 - 0.00059 20.1 0.0 0.0035 17.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) Muted PF14942.6 EAY00420.1 - 0.023 15.1 3.3 0.023 15.1 3.3 2.5 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Ank_2 PF12796.7 EAY00421.1 - 1.8e-40 137.4 0.6 8.9e-16 58.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00421.1 - 3.7e-21 74.9 0.0 4.2e-09 36.5 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00421.1 - 2.1e-20 72.2 0.0 0.00024 21.4 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAY00421.1 - 8.5e-18 64.5 0.0 4.9e-07 30.2 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00421.1 - 1.7e-15 55.5 0.0 0.018 15.5 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Glyco_hydro_20 PF00728.22 EAY00421.1 - 0.025 14.0 1.5 0.036 13.5 1.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain DUF2115 PF09888.9 EAY00421.1 - 7.3 7.1 12.1 4.8 7.7 6.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) LMBR1 PF04791.16 EAY00421.1 - 8.3 5.2 6.5 11 4.8 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HMG_box PF00505.19 EAY00425.1 - 0.00097 19.5 0.5 0.00097 19.5 0.5 1.8 1 1 1 2 2 2 1 HMG (high mobility group) box Peptidase_S49_N PF08496.10 EAY00425.1 - 1.7 8.7 8.7 1.8 8.6 8.7 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Selenoprotein_S PF06936.11 EAY00425.1 - 6.2 6.6 13.1 7 6.4 13.1 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) PH PF00169.29 EAY00426.1 - 1.2e-11 45.1 0.9 2.4e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EAY00426.1 - 0.025 15.0 3.7 0.31 11.5 3.7 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Bac_rhamnosid6H PF17389.2 EAY00426.1 - 0.11 11.7 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain AhpC-TSA PF00578.21 EAY00427.1 - 5.8e-38 129.6 0.0 8.1e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAY00427.1 - 3.6e-16 59.2 0.0 4.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAY00427.1 - 2.3e-11 43.4 0.1 4.6e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF2079 PF09852.9 EAY00428.1 - 0.31 9.8 0.9 0.4 9.5 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Ank PF00023.30 EAY00430.1 - 1.8e-43 145.1 9.9 2.9e-07 30.6 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.7 EAY00430.1 - 1.5e-42 144.0 16.6 9.6e-13 48.5 0.3 6.0 2 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00430.1 - 3.1e-39 128.5 11.9 1.5e-06 28.0 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAY00430.1 - 1.1e-37 127.8 9.4 6.2e-13 49.0 0.3 6.9 3 2 5 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00430.1 - 8.6e-30 102.5 9.4 8.6e-30 102.5 9.4 5.4 4 3 3 7 7 7 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY00430.1 - 1.1e-29 102.0 6.8 6.3e-09 35.9 0.2 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Cnd1 PF12717.7 EAY00430.1 - 0.044 13.8 2.2 0.06 13.4 0.2 2.2 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF1048 PF06304.11 EAY00430.1 - 0.055 13.9 0.4 0.5 10.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) DUF433 PF04255.14 EAY00431.1 - 0.012 15.5 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF433) GerE PF00196.19 EAY00431.1 - 0.17 11.5 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sulfatase PF00884.23 EAY00432.1 - 3.5e-16 59.5 0.3 4.7e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 Sulfatase GCP_N_terminal PF17681.1 EAY00433.1 - 1.8e-19 70.5 1.0 3.9e-19 69.4 1.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAY00433.1 - 9.1e-06 25.3 1.2 0.00016 21.3 0.1 2.7 1 1 1 3 3 3 1 Gamma tubulin complex component C-terminal Cep57_CLD_2 PF14197.6 EAY00433.1 - 0.39 10.8 1.5 4.1 7.6 0.0 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 EAY00434.1 - 5e-22 77.9 7.9 7e-22 77.4 7.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit HrpB7 PF09486.10 EAY00434.1 - 1.8e-05 25.2 1.5 2.3e-05 24.9 1.5 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) FAT PF02259.23 EAY00434.1 - 0.018 14.3 1.5 0.022 14.0 1.5 1.2 1 0 0 1 1 1 0 FAT domain ZapB PF06005.12 EAY00434.1 - 0.11 13.0 15.8 0.35 11.3 7.6 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DDE_Tnp_IS1 PF03400.13 EAY00434.1 - 0.13 12.6 0.1 8.7 6.7 0.0 2.1 2 0 0 2 2 2 0 IS1 transposase DUF848 PF05852.11 EAY00434.1 - 0.19 11.8 6.2 0.061 13.4 2.6 1.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) LRRFIP PF09738.9 EAY00434.1 - 0.29 10.6 11.7 0.29 10.6 5.0 2.0 2 0 0 2 2 2 0 LRRFIP family Prefoldin PF02996.17 EAY00434.1 - 0.42 10.5 9.1 0.38 10.7 1.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 EAY00434.1 - 1.2 9.2 15.6 2.9 7.9 7.1 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 EAY00434.1 - 1.7 9.2 12.7 0.74 10.3 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 EAY00434.1 - 2.9 6.7 13.3 48 2.7 13.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5595 PF18077.1 EAY00434.1 - 5.8 7.1 9.9 2.9 8.0 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) TTL PF03133.15 EAY00435.1 - 3.5e-10 39.5 5.3 8.9e-09 34.9 1.3 2.7 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family HEPN-like_int PF18867.1 EAY00435.1 - 0.059 13.2 0.4 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 HEPN-like integron domain PAP_assoc PF03828.19 EAY00436.1 - 1.1e-11 44.8 0.1 2e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAY00436.1 - 0.002 18.4 0.0 0.018 15.3 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAY00436.1 - 0.042 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase YabA PF06156.13 EAY00437.1 - 0.00046 20.8 37.3 0.13 12.9 9.2 4.6 1 1 4 5 5 5 3 Initiation control protein YabA bZIP_1 PF00170.21 EAY00437.1 - 0.014 15.4 0.1 0.014 15.4 0.1 5.5 4 1 1 6 6 6 0 bZIP transcription factor ZapB PF06005.12 EAY00437.1 - 0.02 15.3 35.6 0.77 10.2 0.2 4.9 3 2 1 4 4 4 0 Cell division protein ZapB KASH_CCD PF14662.6 EAY00437.1 - 0.17 11.7 42.7 0.17 11.7 12.6 3.3 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-H PF05837.12 EAY00437.1 - 0.28 11.6 35.5 0.19 12.1 6.5 4.4 2 1 2 4 4 4 0 Centromere protein H (CENP-H) GAS PF13851.6 EAY00437.1 - 0.44 9.9 39.8 1.7 7.9 15.1 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 EAY00437.1 - 0.59 10.3 28.6 0.058 13.5 2.2 5.3 3 3 2 5 5 5 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 EAY00437.1 - 0.72 10.2 0.1 0.72 10.2 0.1 5.6 4 2 2 6 6 6 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 EAY00437.1 - 0.85 9.6 41.3 0.34 10.9 8.0 4.2 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4686 PF15742.5 EAY00437.1 - 2.2 7.3 44.0 0.34 10.0 13.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) DivIC PF04977.15 EAY00437.1 - 2.4 8.0 35.7 0.26 11.1 0.2 5.0 3 1 1 4 4 4 0 Septum formation initiator DUF501 PF04417.12 EAY00437.1 - 4.3 7.2 9.3 1.1 9.0 0.4 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF501) ATG16 PF08614.11 EAY00437.1 - 4.3 7.5 37.3 5.5 7.2 13.6 3.8 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EAY00437.1 - 5.8 7.4 41.1 3 8.4 11.4 3.9 1 1 3 4 4 4 0 Apg6 coiled-coil region TMPIT PF07851.13 EAY00437.1 - 7.4 5.7 33.3 2.8 7.1 11.9 3.0 1 1 2 3 3 3 0 TMPIT-like protein Rootletin PF15035.6 EAY00437.1 - 7.4 6.5 33.4 0.7 9.9 10.9 3.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Ank_4 PF13637.6 EAY00438.1 - 8.7e-10 38.9 0.6 5.2e-06 26.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY00438.1 - 4.1e-08 33.3 0.1 2.1e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAY00438.1 - 1.9e-06 28.4 0.3 4.6e-06 27.1 0.3 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00438.1 - 4.9e-06 26.5 0.2 0.00077 19.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAY00438.1 - 5e-06 26.7 0.3 0.0073 16.6 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) LRR_5 PF13306.6 EAY00439.1 - 6.3e-18 65.0 13.0 2.7e-16 59.7 5.5 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00439.1 - 0.0043 16.8 0.0 0.045 13.5 0.0 2.5 2 1 1 3 3 3 1 Leucine rich repeat MSL2-CXC PF16682.5 EAY00439.1 - 0.053 13.6 2.3 0.1 12.8 2.3 1.5 1 0 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 LRR_4 PF12799.7 EAY00441.1 - 3.3e-19 68.7 35.6 1.7e-06 28.3 3.1 5.8 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAY00441.1 - 1.2e-18 66.6 32.3 4.7e-08 32.7 1.0 4.6 3 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EAY00441.1 - 2.1e-11 43.6 11.1 1.2e-05 24.9 0.9 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EAY00441.1 - 1.2e-07 31.2 18.8 0.054 13.6 0.2 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 EAY00441.1 - 0.00011 22.3 26.9 1.2 9.9 0.7 8.1 5 3 1 6 6 6 2 Leucine Rich Repeat LRR_3 PF07725.12 EAY00441.1 - 0.17 11.8 7.1 23 5.0 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat UVR PF02151.19 EAY00442.1 - 0.0004 20.0 6.8 0.0017 18.0 0.1 3.5 2 1 0 2 2 2 1 UvrB/uvrC motif MalM PF07148.12 EAY00442.1 - 0.17 11.7 3.3 0.82 9.5 0.4 2.6 1 1 1 2 2 2 0 Maltose operon periplasmic protein precursor (MalM) V-ATPase_G PF03179.15 EAY00442.1 - 5.6 7.6 40.4 0.87 10.2 18.8 3.4 1 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit DUF4061 PF13270.6 EAY00442.1 - 9.4 6.6 17.6 4.6 7.6 1.0 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4061) DUF2935 PF11155.8 EAY00442.1 - 9.8 6.5 14.5 0.81 10.0 4.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) TetR_C_5 PF08360.11 EAY00443.1 - 0.032 14.4 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Pkinase PF00069.25 EAY00444.1 - 8.6e-23 81.0 0.6 9.8e-23 80.8 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00444.1 - 9.5e-13 48.0 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00444.1 - 0.0047 16.3 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAY00444.1 - 0.0083 15.8 0.2 1.4 8.5 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAY00444.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAY00444.1 - 0.045 12.5 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FadA PF09403.10 EAY00444.1 - 0.089 13.3 0.6 0.15 12.5 0.6 1.4 1 0 0 1 1 1 0 Adhesion protein FadA ROS_MUCR PF05443.11 EAY00444.1 - 0.1 12.6 0.4 0.57 10.2 0.3 1.9 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Nuc_rec_co-act PF08815.10 EAY00444.1 - 0.19 11.6 0.2 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Nuclear receptor coactivator Tcp10_C PF07202.13 EAY00445.1 - 1.7e-14 54.2 1.4 1.7e-14 54.2 1.4 1.8 2 0 0 2 2 2 1 T-complex protein 10 C-terminus MORN_2 PF07661.13 EAY00445.1 - 0.007 16.5 0.1 8.5 7.0 0.0 4.4 3 2 0 3 3 3 1 MORN repeat variant tRNA_anti_2 PF13742.6 EAY00445.1 - 0.025 14.8 0.1 0.079 13.2 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Ank_2 PF12796.7 EAY00446.1 - 3.6e-53 178.1 17.4 2.2e-17 63.4 1.4 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00446.1 - 2.7e-34 116.1 6.7 2.5e-06 27.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAY00446.1 - 9.9e-28 96.2 10.3 1.5e-07 31.8 0.3 6.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00446.1 - 6.4e-27 93.3 16.0 2.9e-08 33.8 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00446.1 - 8.3e-25 84.2 9.1 3.4e-05 23.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat UPF0180 PF03698.13 EAY00446.1 - 0.24 11.6 3.7 13 6.0 0.0 3.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF3447 PF11929.8 EAY00446.1 - 2.6 8.1 16.8 7.1 6.7 5.5 3.8 1 1 3 5 5 5 0 Domain of unknown function (DUF3447) HALZ PF02183.18 EAY00447.1 - 0.002 18.3 0.4 0.0038 17.4 0.4 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 EAY00447.1 - 0.0036 17.4 0.9 0.0058 16.7 0.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF4635 PF15466.6 EAY00447.1 - 0.0038 16.8 0.2 0.0047 16.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) ZapB PF06005.12 EAY00447.1 - 0.013 16.0 4.1 0.028 14.9 4.0 1.5 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EAY00447.1 - 0.014 15.1 0.3 0.022 14.5 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Leu_zip PF15294.6 EAY00447.1 - 0.015 14.8 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Leucine zipper DUF4482 PF14818.6 EAY00447.1 - 0.04 14.8 0.5 0.058 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DivIVA PF05103.13 EAY00447.1 - 0.05 13.7 2.2 0.066 13.3 2.1 1.3 1 1 0 1 1 1 0 DivIVA protein TSC22 PF01166.18 EAY00447.1 - 0.098 13.0 1.7 0.17 12.2 1.7 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family BRI3BP PF14965.6 EAY00447.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 V_ATPase_I PF01496.19 EAY00447.1 - 0.14 10.0 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 EAY00447.1 - 0.17 12.0 2.4 0.37 10.9 2.3 1.6 2 0 0 2 2 2 0 Swi5 bZIP_2 PF07716.15 EAY00447.1 - 0.2 11.8 4.8 0.39 10.8 4.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper IFP_35_N PF07334.13 EAY00447.1 - 0.71 10.0 5.4 0.23 11.6 2.9 1.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GCN5L1 PF06320.13 EAY00448.1 - 5.5e-17 62.0 10.7 6.1e-17 61.8 10.7 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) EzrA PF06160.12 EAY00448.1 - 0.0025 16.0 4.3 0.0072 14.6 1.9 1.9 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA PL48 PF15903.5 EAY00448.1 - 0.007 15.4 0.9 0.0073 15.3 0.9 1.0 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Laminin_II PF06009.12 EAY00448.1 - 0.018 15.0 1.9 0.021 14.9 0.2 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 EAY00448.1 - 0.029 14.4 2.4 0.068 13.2 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EAY00448.1 - 0.042 13.9 10.7 0.71 9.9 10.7 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 EAY00448.1 - 0.051 13.6 0.5 1.5 8.8 0.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MutS_III PF05192.18 EAY00448.1 - 0.091 13.0 1.3 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 MutS domain III JAKMIP_CC3 PF16034.5 EAY00448.1 - 0.16 11.9 6.5 0.34 10.8 6.4 1.6 1 1 0 1 1 1 0 JAKMIP CC3 domain Rx_N PF18052.1 EAY00448.1 - 0.17 12.2 6.2 0.033 14.5 1.7 1.9 1 1 1 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 EAY00448.1 - 0.21 12.1 2.5 2.2 8.8 0.1 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EAY00448.1 - 3.5 7.9 11.6 0.31 11.3 1.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AA_permease PF00324.21 EAY00449.1 - 1.8e-71 241.2 49.3 4.1e-71 240.0 49.3 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAY00449.1 - 3.6e-34 118.3 51.7 9.8e-34 116.9 51.7 1.6 1 1 0 1 1 1 1 Amino acid permease MSP1a PF11670.8 EAY00449.1 - 0.0042 16.4 1.1 0.051 12.9 0.0 2.3 2 0 0 2 2 2 1 Major surface protein 1a (MSP1a) DUF2244 PF10003.9 EAY00449.1 - 0.73 9.5 0.0 0.73 9.5 0.0 4.2 4 0 0 4 4 4 0 Integral membrane protein (DUF2244) AbiJ_NTD4 PF18863.1 EAY00451.1 - 0.034 14.6 0.5 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAY00451.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 VirK protein HECT PF00632.25 EAY00452.1 - 1.7e-28 100.0 4.3 2.7e-23 82.9 0.1 3.7 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) DUF4969 PF16339.5 EAY00452.1 - 0.0067 16.8 0.1 0.049 14.0 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4969) TMP PF05017.14 EAY00454.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00455.1 - 0.093 13.2 0.7 0.2 12.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF3839 PF12943.7 EAY00457.1 - 7.5e-155 513.4 14.1 9.2e-155 513.1 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAY00457.1 - 0.03 14.5 0.8 0.074 13.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 Fez1 PF06818.15 EAY00457.1 - 0.052 14.0 1.3 0.097 13.1 0.1 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAY00457.1 - 0.31 11.5 7.8 1.2 9.7 0.8 3.1 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAY00458.1 - 0.00065 20.2 0.2 0.0014 19.1 0.2 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY00458.1 - 0.0071 16.2 0.2 0.018 14.9 0.2 1.8 1 1 0 1 1 1 1 KilA-N domain Antigen_Bd37 PF11641.8 EAY00459.1 - 0.081 12.4 0.1 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein TFIIA PF03153.13 EAY00460.1 - 0.31 11.0 11.6 0.32 10.9 11.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_5 PF13306.6 EAY00461.1 - 2.5e-121 399.3 92.5 2.9e-31 108.1 15.0 6.0 2 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00461.1 - 5.4e-19 67.7 6.8 0.061 13.1 0.0 9.0 7 3 2 9 9 9 7 Leucine rich repeat Chromo PF00385.24 EAY00463.1 - 7 6.6 9.9 0.55 10.2 4.4 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_MLP1_2 PF07926.12 EAY00465.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY00465.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY00465.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family DUF4108 PF13390.6 EAY00466.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) AAA PF00004.29 EAY00467.1 - 2.2e-41 141.4 0.0 5.8e-41 140.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EAY00467.1 - 9.5e-22 76.8 0.1 1e-20 73.4 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EAY00467.1 - 1.1e-09 38.2 0.1 2.3e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EAY00467.1 - 2.8e-09 36.6 0.0 8.6e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAY00467.1 - 3.8e-07 30.2 0.0 2.3e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAY00467.1 - 1.2e-05 25.8 0.6 0.0021 18.5 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAY00467.1 - 4.5e-05 23.7 0.1 0.001 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EAY00467.1 - 7.1e-05 22.2 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EAY00467.1 - 9.7e-05 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EAY00467.1 - 0.00014 22.1 0.0 0.00061 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EAY00467.1 - 0.0002 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EAY00467.1 - 0.00033 20.3 0.3 0.17 11.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EAY00467.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EAY00467.1 - 0.00085 19.5 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAY00467.1 - 0.0018 18.8 0.0 0.0041 17.6 0.0 1.7 2 0 0 2 2 1 1 ABC transporter DUF815 PF05673.13 EAY00467.1 - 0.0026 17.0 0.0 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EAY00467.1 - 0.0078 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Bacterial dnaA protein RNA_helicase PF00910.22 EAY00467.1 - 0.0085 16.5 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 EAY00467.1 - 0.017 14.5 0.2 4.5 6.6 0.0 2.5 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 EAY00467.1 - 0.018 14.6 0.1 0.053 13.0 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EAY00467.1 - 0.02 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAY00467.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 EAY00467.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_17 PF13207.6 EAY00467.1 - 0.033 14.6 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MAGI_u1 PF16663.5 EAY00467.1 - 0.034 14.2 0.2 0.085 12.9 0.2 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI AAA_18 PF13238.6 EAY00467.1 - 0.04 14.5 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EAY00467.1 - 0.055 12.7 0.1 2.5 7.3 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.18 EAY00467.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EAY00467.1 - 0.081 12.6 0.0 0.27 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2791 PF10923.8 EAY00467.1 - 0.082 11.7 0.5 1.8 7.3 0.0 2.4 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) Sigma54_activ_2 PF14532.6 EAY00467.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EAY00467.1 - 0.16 11.9 0.2 1.1 9.2 0.0 2.5 2 1 1 3 3 2 0 NACHT domain AAA_11 PF13086.6 EAY00468.1 - 4e-14 53.0 0.1 7.1e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 EAY00468.1 - 7.7e-14 51.9 14.0 2.1e-12 47.2 14.0 2.5 1 1 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 EAY00468.1 - 1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAY00468.1 - 2.3e-06 28.0 0.0 3.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAY00468.1 - 0.00023 20.8 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EAY00468.1 - 0.00035 20.1 0.1 0.00068 19.1 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_23 PF13476.6 EAY00468.1 - 0.00042 20.9 0.9 0.0011 19.5 0.1 2.0 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EAY00468.1 - 0.00058 19.0 0.0 0.00084 18.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 EAY00468.1 - 0.0007 19.6 0.1 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 EAY00468.1 - 0.0042 17.5 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 EAY00468.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 EAY00468.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 EAY00468.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EAY00468.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAY00468.1 - 0.033 14.6 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EAY00468.1 - 0.033 14.7 0.4 0.076 13.5 0.1 1.8 1 1 1 2 2 2 0 ABC transporter DUF2075 PF09848.9 EAY00468.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SMC_N PF02463.19 EAY00468.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PIF1 PF05970.14 EAY00468.1 - 0.042 13.0 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 EAY00468.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAY00468.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3626 PF12294.8 EAY00468.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) cobW PF02492.19 EAY00468.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EAY00468.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MukB PF04310.12 EAY00468.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 MukB N-terminal AAA_18 PF13238.6 EAY00468.1 - 0.13 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAY00468.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EAY00468.1 - 0.23 11.8 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_12 PF13087.6 EAY00469.1 - 2.5e-52 177.4 0.0 3.5e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAY00469.1 - 3e-15 56.7 0.1 4.6e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAY00469.1 - 3.4e-05 23.7 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EAY00469.1 - 0.00057 20.2 0.0 0.0036 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAY00469.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EAY00469.1 - 0.21 11.4 0.0 0.51 10.2 0.0 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain F5_F8_type_C PF00754.25 EAY00471.1 - 2.8e-06 27.5 0.0 9.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Imm5 PF14423.6 EAY00471.1 - 0.0033 17.7 0.7 0.0052 17.0 0.7 1.2 1 0 0 1 1 1 1 Immunity protein Imm5 Mucin PF01456.17 EAY00473.1 - 0.044 13.8 11.5 0.09 12.8 11.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Gly_rich PF12810.7 EAY00474.1 - 3.8e-16 59.8 24.3 6.1e-16 59.1 24.3 1.3 1 0 0 1 1 1 1 Glycine rich protein VSP PF03302.13 EAY00474.1 - 1 8.1 51.9 0.85 8.4 2.3 3.9 2 1 0 3 3 3 0 Giardia variant-specific surface protein LRR_5 PF13306.6 EAY00475.1 - 2.2e-132 435.0 100.0 7.1e-30 103.6 3.0 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00475.1 - 2.7e-25 87.9 6.0 0.00067 19.4 0.1 10.6 4 3 10 14 14 14 12 Leucine rich repeat Phage_rep_org_N PF09681.10 EAY00475.1 - 0.058 13.3 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) CENP-N PF05238.13 EAY00475.1 - 0.34 10.2 0.9 0.53 9.5 0.9 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like LRR_4 PF12799.7 EAY00475.1 - 1.3 9.5 33.7 0.26 11.8 0.3 10.1 6 3 4 10 10 10 0 Leucine Rich repeats (2 copies) Aa_trans PF01490.18 EAY00476.1 - 6.9e-22 77.7 34.4 8.4e-22 77.4 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MULE PF10551.9 EAY00477.1 - 3e-08 34.0 0.1 7.2e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAY00477.1 - 0.0082 15.0 0.2 0.017 14.0 0.2 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAY00477.1 - 0.011 15.4 0.3 0.054 13.2 0.2 1.9 1 1 1 2 2 2 0 Transposase FAR1 PF03101.15 EAY00477.1 - 0.093 13.4 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3839 PF12943.7 EAY00478.1 - 2.9e-153 508.3 12.7 3.6e-153 507.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY00478.1 - 0.11 12.4 0.8 0.33 10.8 0.3 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAY00478.1 - 0.5 10.9 4.3 1.3 9.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glu-tRNAGln PF02686.15 EAY00478.1 - 2.2 8.6 4.6 0.7 10.2 0.9 2.2 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF1493 PF07377.12 EAY00479.1 - 0.066 13.7 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY00480.1 - 0.13 13.0 7.8 6.8 7.8 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAY00480.1 - 4.3 7.3 8.2 4.7 7.2 8.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PSP PF04046.16 EAY00481.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Pkinase PF00069.25 EAY00482.1 - 2e-71 240.4 0.5 2.9e-71 240.0 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00482.1 - 2.1e-45 155.1 0.2 2.8e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY00482.1 - 1.2e-09 37.6 0.7 2.6e-09 36.5 0.7 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAY00482.1 - 3.2e-09 36.5 0.0 7.7e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EAY00482.1 - 1.8e-08 34.2 1.3 2.8e-08 33.6 0.3 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EAY00482.1 - 0.0051 15.6 0.5 0.0071 15.2 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EAY00482.1 - 0.0054 16.9 0.1 0.021 15.0 0.0 2.0 3 0 0 3 3 3 1 ABC1 family APH PF01636.23 EAY00482.1 - 0.17 11.8 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Stork_head PF10264.9 EAY00484.1 - 0.83 9.9 4.0 2.9 8.1 0.1 3.4 4 0 0 4 4 4 0 Winged helix Storkhead-box1 domain Pkinase PF00069.25 EAY00485.1 - 8.4e-48 163.0 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00485.1 - 5.2e-26 91.5 0.0 6.6e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00485.1 - 4.3e-10 39.4 0.0 6.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAY00485.1 - 0.0025 16.8 0.2 0.0038 16.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY00485.1 - 0.055 12.8 0.3 0.093 12.1 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAY00485.1 - 0.28 9.9 0.4 0.46 9.2 0.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase Leu_zip PF15294.6 EAY00487.1 - 0.0001 21.9 13.6 0.0012 18.5 13.6 2.0 1 1 0 1 1 1 1 Leucine zipper TAL_FSA PF00923.19 EAY00487.1 - 0.0031 16.9 0.4 0.0045 16.4 0.3 1.3 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase COMPASS-Shg1 PF05205.12 EAY00487.1 - 0.03 15.0 3.3 2.2 9.0 0.4 2.6 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 COPIIcoated_ERV PF07970.12 EAY00488.1 - 5.2e-45 154.0 0.4 2.3e-43 148.6 0.4 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAY00488.1 - 1.9e-22 79.4 0.0 4.3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LRR_5 PF13306.6 EAY00489.1 - 2e-135 444.8 107.4 3.7e-36 123.9 5.2 6.0 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00489.1 - 1.9e-18 65.9 10.8 0.004 16.9 0.0 9.9 5 2 8 14 14 14 8 Leucine rich repeat LRR_4 PF12799.7 EAY00489.1 - 0.021 15.3 27.9 2.9 8.4 0.0 9.5 7 4 2 10 10 10 0 Leucine Rich repeats (2 copies) Myb_DNA-binding PF00249.31 EAY00490.1 - 1.6e-08 34.6 0.0 5.2e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00490.1 - 0.0051 17.0 0.1 0.16 12.3 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sec16 PF12932.7 EAY00490.1 - 0.089 13.4 1.7 16 6.1 0.7 2.7 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DTHCT PF08070.11 EAY00490.1 - 0.31 11.8 12.6 6.3 7.6 4.3 3.1 2 0 0 2 2 2 0 DTHCT (NUC029) region MANEC PF07502.14 EAY00491.1 - 0.0043 17.3 0.6 0.0055 17.0 0.6 1.2 1 0 0 1 1 1 1 MANEC domain PAN_3 PF08277.12 EAY00491.1 - 0.029 14.2 3.3 0.029 14.2 3.3 1.9 1 1 1 2 2 2 0 PAN-like domain DUF4091 PF13320.6 EAY00492.1 - 0.2 11.8 0.5 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) KNOX2 PF03791.13 EAY00493.1 - 0.0093 15.5 0.7 3.8 7.1 0.0 3.3 3 0 0 3 3 3 2 KNOX2 domain ADIP PF11559.8 EAY00493.1 - 0.018 15.1 11.3 0.018 15.1 11.3 5.2 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 EAY00493.1 - 0.049 14.1 1.2 0.049 14.1 1.2 5.4 3 2 4 7 7 7 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EAY00493.1 - 1.3 9.2 50.5 0.15 12.2 9.3 4.5 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 EAY00493.1 - 1.7 6.7 59.3 0.098 10.8 15.2 2.9 1 1 2 3 3 3 0 HOOK protein MEDS PF14417.6 EAY00494.1 - 0.03 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DNA_pol_A_exo1 PF01612.20 EAY00495.1 - 4.8e-11 42.7 0.2 1.2e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease EELM2 PF15863.5 EAY00495.1 - 0.093 12.9 5.0 0.35 11.0 1.1 2.4 2 0 0 2 2 2 0 Extended EGL-27 and MTA1 homology domain zf-C2H2_3rep PF18868.1 EAY00495.1 - 1.6 9.4 8.1 6.5 7.5 0.1 3.6 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EAY00495.1 - 1.7 9.0 17.2 0.97 9.8 5.8 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Rad60-SLD PF11976.8 EAY00495.1 - 2.9 7.8 5.3 0.74 9.7 0.5 2.7 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like zf-BED PF02892.15 EAY00495.1 - 7.8 6.6 9.2 0.88 9.6 0.2 3.5 3 0 0 3 3 3 0 BED zinc finger LRR_5 PF13306.6 EAY00497.1 - 3.2e-102 337.5 48.7 9.8e-36 122.5 9.0 4.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00497.1 - 3.8e-24 84.2 0.0 0.0026 17.5 0.0 8.0 4 2 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EAY00497.1 - 1.8e-06 28.1 6.7 5.5 7.6 0.0 7.3 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) CLP1_P PF16575.5 EAY00498.1 - 8.4e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EAY00498.1 - 7.3e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_22 PF13401.6 EAY00498.1 - 0.0055 17.0 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EAY00498.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EAY00498.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.6 EAY00498.1 - 0.048 14.1 0.1 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Haem_oxygenas_2 PF14518.6 EAY00498.1 - 0.055 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme AAA_25 PF13481.6 EAY00498.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP1_N PF16573.5 EAY00498.1 - 0.07 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor HECT PF00632.25 EAY00499.1 - 4.1e-35 121.7 2.8 2.1e-34 119.4 2.8 2.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Syja_N PF02383.18 EAY00500.1 - 4.1e-34 118.3 0.1 1.1e-33 116.9 0.1 1.7 1 1 0 1 1 1 1 SacI homology domain zf-C4_ClpX PF06689.13 EAY00500.1 - 0.054 13.4 0.4 0.17 11.8 0.4 1.8 1 0 0 1 1 1 0 ClpX C4-type zinc finger Phage_term_sma PF07141.11 EAY00500.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Ski2_N PF17911.1 EAY00502.1 - 0.0047 16.7 0.1 0.0047 16.7 0.1 2.2 2 1 1 3 3 3 1 Ski2 N-terminal region DUF4279 PF14106.6 EAY00502.1 - 0.14 12.4 5.9 4.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) VRP3 PF03536.15 EAY00502.1 - 0.17 11.4 4.9 5.9 6.3 0.1 2.5 1 1 1 2 2 2 0 Salmonella virulence-associated 28kDa protein DUF2314 PF10077.9 EAY00502.1 - 0.18 11.9 3.4 4.3 7.4 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) DUF2968 PF11180.8 EAY00502.1 - 0.76 9.4 28.1 0.15 11.7 10.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) LMBR1 PF04791.16 EAY00502.1 - 4.9 5.9 21.8 8.7 5.1 21.7 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.6 EAY00502.1 - 10 4.6 32.4 3.2 6.3 11.8 2.1 1 1 1 2 2 2 0 AAA domain MGC-24 PF05283.11 EAY00503.1 - 0.064 13.7 1.9 0.077 13.4 1.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RepL PF05732.11 EAY00503.1 - 0.18 11.2 1.0 0.28 10.6 1.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) GAS PF13851.6 EAY00504.1 - 0.0046 16.3 16.8 0.006 16.0 16.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YolD PF08863.10 EAY00504.1 - 0.25 11.4 10.3 0.089 12.9 3.5 2.3 1 1 1 2 2 2 0 YolD-like protein DUF2730 PF10805.8 EAY00504.1 - 0.3 11.2 5.1 0.25 11.5 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Atg14 PF10186.9 EAY00504.1 - 0.48 9.5 8.2 0.61 9.1 8.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EAY00504.1 - 0.84 8.4 18.4 2.1 7.2 8.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4404 PF14357.6 EAY00504.1 - 1.2 9.9 9.0 0.46 11.2 4.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Macoilin PF09726.9 EAY00504.1 - 2.1 6.8 12.9 2.3 6.7 12.9 1.0 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 EAY00504.1 - 2.6 8.2 12.1 3.7 7.7 0.6 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family VASP_tetra PF08776.11 EAY00504.1 - 2.9 7.6 12.1 2.4 7.8 8.2 2.6 2 1 0 2 2 2 0 VASP tetramerisation domain XhlA PF10779.9 EAY00504.1 - 3.9 7.8 14.2 1.4 9.1 2.3 2.8 1 1 3 4 4 4 0 Haemolysin XhlA CENP-H PF05837.12 EAY00504.1 - 6 7.3 14.3 16 5.9 8.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 EAY00504.1 - 6.6 6.8 16.3 7.9 6.5 16.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EAY00504.1 - 7.3 5.8 11.4 8.2 5.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EAY00504.1 - 8.3 7.1 13.4 23 5.7 13.4 1.8 1 1 0 1 1 1 0 Initiation control protein YabA RNase_J_C PF17770.1 EAY00505.1 - 0.011 16.7 0.3 0.02 15.9 0.3 1.5 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain DUF1664 PF07889.12 EAY00505.1 - 0.13 12.3 2.0 0.18 11.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2576 PF10845.8 EAY00506.1 - 0.088 12.4 0.1 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Ank_2 PF12796.7 EAY00507.1 - 1.5e-77 256.2 7.8 1.7e-18 67.0 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00507.1 - 2.1e-49 163.9 0.0 4e-06 27.0 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EAY00507.1 - 2.1e-44 149.3 0.0 1e-07 32.3 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00507.1 - 1.2e-43 146.6 0.0 2.3e-07 30.9 0.0 8.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00507.1 - 1.1e-31 105.3 0.0 0.0042 17.5 0.0 9.3 9 0 0 9 9 9 5 Ankyrin repeat DUF1664 PF07889.12 EAY00507.1 - 0.0031 17.6 5.9 0.0055 16.7 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF1897 PF09005.10 EAY00507.1 - 0.0064 15.9 3.8 1.3e+02 2.1 0.0 6.6 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) HemX PF04375.14 EAY00507.1 - 0.013 14.8 4.0 0.022 14.1 4.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med21 PF11221.8 EAY00507.1 - 0.018 15.3 2.5 0.039 14.2 2.5 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Fib_alpha PF08702.10 EAY00507.1 - 0.052 13.7 11.0 0.034 14.3 6.9 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TACC_C PF05010.14 EAY00507.1 - 0.058 13.2 12.8 0.11 12.2 12.6 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Pfk_N PF18468.1 EAY00507.1 - 0.073 13.5 1.1 1.2e+02 3.2 0.0 3.8 3 0 0 3 3 3 0 Phosphofructokinase N-terminal domain yeast DAP_B PF07930.12 EAY00507.1 - 0.077 13.0 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 D-aminopeptidase, domain B Bile_Hydr_Trans PF04775.14 EAY00507.1 - 0.11 12.6 0.3 32 4.6 0.1 3.3 2 1 1 3 3 3 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region BBS2_Mid PF14783.6 EAY00507.1 - 0.12 12.4 0.9 90 3.2 0.0 4.6 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region T3SS_ATPase_C PF18269.1 EAY00507.1 - 0.13 12.1 14.7 16 5.4 0.0 6.5 8 0 0 8 8 8 0 T3SS EscN ATPase C-terminal domain MCU PF04678.13 EAY00507.1 - 0.19 11.8 2.1 0.41 10.7 2.1 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Nas2_N PF18265.1 EAY00507.1 - 0.77 9.7 4.5 0.74 9.8 1.8 2.4 1 1 1 2 2 2 0 Nas2 N_terminal domain LMBR1 PF04791.16 EAY00507.1 - 0.93 8.3 3.0 1.5 7.7 3.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EAY00507.1 - 1 10.0 9.8 2 9.1 9.0 2.0 1 1 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 EAY00507.1 - 1.4 8.1 8.1 2.2 7.4 8.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2115 PF09888.9 EAY00507.1 - 1.9 9.0 10.1 3.9 8.0 5.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) SlyX PF04102.12 EAY00507.1 - 2 9.1 5.4 5.7 7.6 5.4 1.7 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 EAY00507.1 - 8.9 6.2 8.4 6.8 6.5 6.3 1.9 2 0 0 2 2 1 0 Septum formation initiator DUF3447 PF11929.8 EAY00508.1 - 5.9e-24 83.8 6.1 1.1e-23 82.9 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00508.1 - 7.9e-06 26.3 0.0 0.0018 18.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00508.1 - 4.4e-05 24.0 0.0 0.39 11.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00508.1 - 0.021 15.1 0.0 0.073 13.4 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00508.1 - 0.051 14.1 1.0 19 6.2 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 EAY00508.1 - 0.087 13.3 0.1 2.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat DUF3447 PF11929.8 EAY00510.1 - 1.1e-07 31.7 3.1 1.1e-07 31.7 3.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00510.1 - 2.1e-07 31.5 0.0 0.00074 20.1 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00510.1 - 1e-05 26.0 0.0 5.8e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00510.1 - 7.7e-05 22.8 0.0 0.27 11.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat DUF4878 PF12870.7 EAY00510.1 - 0.023 15.0 3.9 0.078 13.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Ank_5 PF13857.6 EAY00510.1 - 0.14 12.5 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3403 PF11883.8 EAY00511.1 - 0.0076 16.3 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3403) KASH_CCD PF14662.6 EAY00512.1 - 0.00025 21.0 29.4 0.00025 21.0 29.4 14.9 3 3 10 13 13 13 1 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 EAY00512.1 - 0.0015 18.7 32.0 0.0015 18.7 32.0 18.0 2 1 13 16 16 16 1 Uncharacterised protein family (UPF0242) N-terminus Anophelin PF10731.9 EAY00512.1 - 0.11 12.4 10.6 0.039 13.8 1.0 3.1 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito EF-hand_6 PF13405.6 EAY00513.1 - 0.003 17.4 2.2 1.5 8.9 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EAY00513.1 - 0.016 15.6 5.0 2.9 8.4 1.9 4.0 3 2 0 3 3 3 0 EF-hand domain pair Phage_AlpA PF05930.12 EAY00513.1 - 0.035 13.9 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) EF-hand_1 PF00036.32 EAY00513.1 - 0.74 9.5 5.4 2.5 7.9 0.4 3.3 3 0 0 3 3 3 0 EF hand Peptidase_C14 PF00656.22 EAY00514.1 - 8.8e-16 58.6 0.1 3.2e-15 56.8 0.1 1.7 1 1 0 1 1 1 1 Caspase domain Gly_rich PF12810.7 EAY00515.1 - 1.5e-49 169.1 52.7 2.4e-49 168.5 52.7 1.2 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAY00515.1 - 1.3e-47 160.9 40.8 3.2e-20 72.4 11.2 3.6 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00515.1 - 0.045 13.5 0.6 26 4.7 0.0 4.1 3 2 0 3 3 3 0 Leucine rich repeat Guanylate_cyc PF00211.20 EAY00516.1 - 1.1e-37 129.5 0.0 3.2e-37 127.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY00516.1 - 1.3e-14 54.3 0.6 3.3e-14 53.0 0.6 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAY00516.1 - 0.00015 21.8 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAY00516.1 - 0.00019 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 EAY00516.1 - 0.013 14.9 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated DUF4134 PF13572.6 EAY00516.1 - 0.056 13.7 0.1 0.056 13.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4134) UCH PF00443.29 EAY00517.1 - 4.1e-19 69.1 7.3 4.1e-19 69.1 7.3 4.8 4 2 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DUF3986 PF13143.6 EAY00517.1 - 0.019 15.9 0.9 0.2 12.6 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) ACDC PF14733.6 EAY00517.1 - 2.9 8.2 16.3 4.8 7.6 0.1 6.3 6 0 0 6 6 6 0 AP2-coincident C-terminal DAG1 PF05454.11 EAY00518.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Orf78 PF06024.12 EAY00518.1 - 0.0025 18.1 0.1 0.0051 17.1 0.1 1.4 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 EAY00518.1 - 0.003 17.5 1.5 0.0066 16.4 1.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 EAY00518.1 - 0.0053 16.9 0.1 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Podoplanin DUF3671 PF12420.8 EAY00518.1 - 0.0075 16.3 0.6 0.016 15.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function RIFIN PF02009.16 EAY00518.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Rifin Adeno_E3_CR2 PF02439.15 EAY00518.1 - 0.012 15.3 2.0 0.023 14.5 2.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EAY00518.1 - 0.016 16.1 0.1 0.044 14.7 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pox_EPC_I2-L1 PF12575.8 EAY00518.1 - 0.04 14.1 0.3 0.089 13.0 0.3 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF5385 PF17359.2 EAY00518.1 - 0.12 12.0 0.4 0.24 10.9 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 EAY00518.1 - 0.24 11.3 1.1 0.49 10.3 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain Gemini_mov PF01708.16 EAY00518.1 - 0.53 10.1 2.9 0.73 9.6 0.5 2.5 2 1 0 2 2 2 0 Geminivirus putative movement protein Insulin_TMD PF17870.1 EAY00518.1 - 7.2 6.8 10.9 1.7 8.7 4.3 2.8 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment LMWPc PF01451.21 EAY00520.1 - 8.2e-29 100.8 0.0 9.5e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Anticodon_1 PF08264.13 EAY00521.1 - 0.11 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA NHS PF15273.6 EAY00521.1 - 0.14 11.2 3.8 1.1 8.2 3.8 2.1 1 1 0 1 1 1 0 NHS-like CD34_antigen PF06365.12 EAY00522.1 - 0.0025 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Peptidase_C69 PF03577.15 EAY00523.1 - 1.9e-118 395.9 0.0 2.2e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C69 Fez1 PF06818.15 EAY00524.1 - 0.00029 21.4 45.4 0.22 12.0 18.1 3.2 1 1 2 3 3 3 3 Fez1 Tropomyosin_1 PF12718.7 EAY00524.1 - 0.00041 20.5 46.6 0.8 9.9 17.7 4.2 2 1 2 4 4 4 3 Tropomyosin like Tropomyosin PF00261.20 EAY00524.1 - 0.001 18.5 42.1 0.008 15.6 12.0 4.2 1 1 2 4 4 4 3 Tropomyosin Spc7 PF08317.11 EAY00524.1 - 0.023 13.6 54.4 0.34 9.8 5.0 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein NEMO PF11577.8 EAY00524.1 - 0.024 14.6 0.6 0.024 14.6 0.6 4.6 4 1 1 5 5 5 0 NF-kappa-B essential modulator NEMO bZIP_2 PF07716.15 EAY00524.1 - 0.025 14.7 2.3 0.025 14.7 2.3 5.5 6 0 0 6 6 6 0 Basic region leucine zipper GAS PF13851.6 EAY00524.1 - 0.082 12.2 57.0 0.038 13.3 8.5 4.8 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 EAY00524.1 - 0.099 12.1 57.8 0.035 13.6 8.8 3.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 EAY00524.1 - 0.16 12.0 51.8 0.91 9.6 12.3 5.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 EAY00524.1 - 0.27 11.8 41.4 0.54 10.9 0.2 5.7 1 1 5 6 6 6 0 Syntaxin 6, N-terminal DUF745 PF05335.13 EAY00524.1 - 0.41 10.4 36.6 0.018 14.7 13.9 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF745) SlyX PF04102.12 EAY00524.1 - 0.67 10.6 40.0 0.2 12.3 1.7 6.9 1 1 5 7 7 7 0 SlyX Leu_zip PF15294.6 EAY00524.1 - 3.6 7.0 54.0 0.37 10.3 25.4 3.6 1 1 3 4 4 4 0 Leucine zipper ADIP PF11559.8 EAY00524.1 - 4.6 7.3 60.9 0.082 13.0 9.0 5.3 2 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EAY00524.1 - 5.5 7.2 52.5 30 4.8 11.4 4.7 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 EAY00524.1 - 9.5 4.2 53.6 2.1 6.4 2.3 3.2 1 1 2 3 3 3 0 HOOK protein Fib_alpha PF08702.10 EAY00524.1 - 9.5 6.4 62.0 9 6.5 12.5 5.3 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Chlam_PMP PF02415.17 EAY00525.1 - 1.4 9.6 4.1 22 5.8 0.4 3.4 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ank_4 PF13637.6 EAY00526.1 - 1.5e-06 28.7 0.5 0.0045 17.5 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00526.1 - 0.00028 21.4 3.9 0.0035 17.9 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PCRF PF03462.18 EAY00526.1 - 0.016 15.1 2.1 0.029 14.2 2.1 1.5 1 0 0 1 1 1 0 PCRF domain Ank_3 PF13606.6 EAY00526.1 - 0.016 15.7 0.1 11 7.0 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat DUF2203 PF09969.9 EAY00526.1 - 0.059 14.1 1.3 1.5 9.6 1.3 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Gag_p19 PF02228.16 EAY00526.1 - 0.065 13.7 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 Major core protein p19 ApoLp-III PF07464.11 EAY00526.1 - 0.28 11.2 10.1 2.6 8.1 0.3 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF1870 PF08965.10 EAY00526.1 - 2.5 8.2 7.3 22 5.1 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1870) DUF16 PF01519.16 EAY00526.1 - 7.2 7.2 17.3 6.1 7.4 5.2 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF16 Na_Ala_symp PF01235.17 EAY00528.1 - 0.0013 18.1 0.4 0.0013 18.1 0.4 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family DUF4448 PF14610.6 EAY00528.1 - 0.015 15.0 0.4 0.025 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EAY00528.1 - 0.12 12.2 1.5 0.23 11.3 1.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family FeoB_associated PF12669.7 EAY00528.1 - 0.38 11.2 4.7 0.81 10.1 4.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Lactamase_B PF00753.27 EAY00529.1 - 4.5e-17 62.7 0.8 1.6e-16 60.9 0.8 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAY00529.1 - 8.6e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EAY00529.1 - 0.00094 18.7 0.1 0.014 14.8 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain PDEase_II PF02112.15 EAY00529.1 - 0.054 12.6 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Guanylate_cyc PF00211.20 EAY00530.1 - 3.9e-40 137.4 0.0 1.5e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY00530.1 - 4.7e-11 42.9 0.8 1.5e-10 41.3 0.8 2.0 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 EAY00530.1 - 2.3e-05 23.9 0.5 7.2e-05 22.3 0.2 2.0 2 0 0 2 2 2 1 Heme NO binding associated PAS PF00989.25 EAY00530.1 - 0.0028 17.6 0.0 0.0081 16.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAY00530.1 - 0.0057 16.7 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAY00530.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold PHO4 PF01384.20 EAY00530.1 - 2 7.4 10.0 0.84 8.6 0.1 2.9 2 1 0 2 2 2 0 Phosphate transporter family FAR1 PF03101.15 EAY00531.1 - 0.014 16.0 0.1 0.027 15.2 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain Pkinase PF00069.25 EAY00532.1 - 3.8e-62 210.0 0.1 5e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00532.1 - 1.1e-38 133.1 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00532.1 - 4.5e-08 32.8 0.0 7.6e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAY00532.1 - 0.00035 20.6 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAY00532.1 - 0.00048 19.8 0.3 0.0013 18.3 0.3 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EAY00532.1 - 0.0005 19.0 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY00532.1 - 0.0011 18.4 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAY00532.1 - 0.004 16.2 0.2 0.0069 15.4 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EAY00532.1 - 0.045 13.4 0.5 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cnd3 PF12719.7 EAY00533.1 - 0.00055 19.2 3.9 0.012 14.8 0.0 4.1 3 2 2 5 5 5 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EAY00533.1 - 0.017 15.3 1.7 0.36 11.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Toxin_R_bind_C PF07951.12 EAY00535.1 - 0.026 14.2 3.4 0.083 12.5 0.5 2.4 2 1 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding PPP5 PF08321.12 EAY00535.1 - 7 7.0 7.3 16 5.8 0.1 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region Ank_2 PF12796.7 EAY00536.1 - 2.6e-44 149.7 18.3 3.5e-13 49.9 1.4 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00536.1 - 2.7e-42 142.6 15.9 1.8e-10 41.1 0.1 9.1 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAY00536.1 - 3.1e-39 131.7 18.9 7e-07 29.4 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAY00536.1 - 3.6e-33 113.2 19.0 1.3e-11 44.5 0.0 5.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00536.1 - 2.7e-29 98.0 13.6 6.8e-06 26.0 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 EAY00536.1 - 2.8e-28 97.7 8.7 2e-26 91.7 1.4 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) F5_F8_type_C PF00754.25 EAY00537.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain PEX11 PF05648.14 EAY00537.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Nic96 PF04097.14 EAY00538.1 - 2.1e-34 119.0 3.6 5.7e-25 87.8 0.1 2.5 3 0 0 3 3 3 2 Nup93/Nic96 DUF3094 PF11293.8 EAY00538.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DotA PF11388.8 EAY00538.1 - 0.19 12.0 1.0 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Phagosome trafficking protein DotA F-box-like_2 PF13013.6 EAY00539.1 - 0.00074 19.5 2.4 0.098 12.6 0.3 2.9 3 0 0 3 3 3 2 F-box-like domain PSP PF04046.16 EAY00541.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00542.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00543.1 - 0.032 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00544.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.3 3 1 1 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAY00544.1 - 0.013 15.3 6.0 0.023 14.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4116 PF13475.6 EAY00544.1 - 0.06 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) EDR1 PF14381.6 EAY00544.1 - 0.061 13.0 0.1 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 MeaB PF03308.16 EAY00544.1 - 0.18 10.7 1.0 0.31 10.0 1.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3417 PF11897.8 EAY00544.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAY00545.1 - 3.7e-55 187.0 3.7 4.3e-55 186.8 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAY00545.1 - 0.011 15.3 0.5 0.012 15.1 0.5 1.0 1 0 0 1 1 1 0 Z1 domain MvaI_BcnI PF15515.6 EAY00545.1 - 0.061 13.1 2.0 1.2 8.9 0.1 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family DUF5398 PF17376.2 EAY00545.1 - 0.26 12.0 2.7 1.3 9.7 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5398) DUF3839 PF12943.7 EAY00546.1 - 7.4e-69 231.9 13.9 3.2e-49 167.6 3.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAY00547.1 - 2.5e-07 30.4 2.7 3.7e-07 29.9 2.7 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAY00547.1 - 0.0045 16.7 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAY00547.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAY00547.1 - 0.061 13.0 0.3 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAY00547.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAY00547.1 - 0.19 11.7 2.2 1.3 9.0 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAY00547.1 - 0.56 10.4 8.4 5.6 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) KilA-N PF04383.13 EAY00549.1 - 4.9e-07 29.6 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAY00550.1 - 3.4e-157 521.1 13.0 4.2e-157 520.8 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY00550.1 - 0.091 13.2 1.5 0.44 11.0 0.2 2.1 2 0 0 2 2 2 0 Fez1 MitMem_reg PF13012.6 EAY00550.1 - 0.12 12.8 0.3 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAY00550.1 - 0.18 12.3 7.4 2.4 8.7 0.7 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY00550.1 - 5.2 7.4 7.4 13 6.1 0.1 3.8 3 2 2 5 5 5 0 Tup N-terminal KilA-N PF04383.13 EAY00551.1 - 6.6e-43 145.1 1.0 1e-42 144.5 0.1 1.8 2 1 0 2 2 2 1 KilA-N domain DUF3213 PF11491.8 EAY00551.1 - 0.0062 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) Pox_A32 PF04665.12 EAY00552.1 - 7.1e-07 28.9 2.8 7.1e-07 28.9 2.8 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00552.1 - 3.2e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAY00552.1 - 0.00013 22.0 3.1 0.00029 20.9 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAY00552.1 - 0.00025 20.8 0.3 0.36 10.5 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein DEAD PF00270.29 EAY00552.1 - 0.00063 19.6 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00552.1 - 0.0013 18.6 0.6 0.0023 17.7 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00552.1 - 0.0021 17.7 2.6 0.013 15.2 0.2 2.7 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00552.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAY00552.1 - 0.069 12.7 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00552.1 - 0.081 13.3 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAY00552.1 - 0.096 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein CutC PF03932.14 EAY00553.1 - 6.3e-82 274.0 0.7 7.7e-82 273.7 0.7 1.1 1 0 0 1 1 1 1 CutC family AP_endonuc_2 PF01261.24 EAY00553.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PT-VENN PF04829.13 EAY00554.1 - 0.2 11.7 2.5 0.31 11.2 2.5 1.2 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAY00555.1 - 5.8e-06 25.9 0.3 6.7e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAY00555.1 - 0.06 13.6 0.5 0.06 13.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Ank_2 PF12796.7 EAY00556.1 - 4.6e-06 27.1 0.0 0.07 13.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00556.1 - 0.00026 21.2 0.0 1.6 9.5 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 EAY00556.1 - 0.0006 19.7 0.8 0.0006 19.7 0.8 2.3 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00556.1 - 0.0022 18.5 0.2 6.6 7.4 0.1 3.5 2 2 0 2 2 2 2 Ankyrin repeats (many copies) ATG16 PF08614.11 EAY00557.1 - 0.0018 18.5 12.3 0.0018 18.5 12.3 8.3 2 2 2 6 6 6 1 Autophagy protein 16 (ATG16) SepF PF04472.12 EAY00557.1 - 0.12 12.7 0.1 0.83 10.0 0.1 2.5 1 0 0 1 1 1 0 Cell division protein SepF CART PF06373.11 EAY00557.1 - 0.53 10.5 6.1 3 8.1 0.3 3.8 3 1 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) TraF_2 PF13729.6 EAY00557.1 - 5.5 6.3 12.3 0.97 8.8 4.8 3.4 1 1 2 3 3 3 0 F plasmid transfer operon, TraF, protein TBK1_ULD PF18396.1 EAY00558.1 - 0.097 12.6 2.4 0.12 12.3 0.7 2.0 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain DUF4887 PF16228.5 EAY00558.1 - 1.9 8.7 8.4 3 8.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Proteasome PF00227.26 EAY00559.1 - 6.4e-41 139.9 0.0 7.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DMAP1_like PF17024.5 EAY00561.1 - 0.028 14.5 0.7 0.078 13.1 0.4 1.9 1 1 0 1 1 1 0 Putative DMAP1-like PSP PF04046.16 EAY00562.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00563.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PTR PF12789.7 EAY00564.1 - 2.5e-55 184.4 33.5 8.3e-34 115.5 17.6 5.6 4 2 1 5 5 5 2 Phage tail repeat like DUF3839 PF12943.7 EAY00565.1 - 2.1e-86 289.4 6.0 2.3e-86 289.2 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Pox_A32 PF04665.12 EAY00566.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAY00566.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAY00566.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAY00566.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) KilA-N PF04383.13 EAY00567.1 - 1.3e-33 115.2 0.6 2.7e-33 114.2 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Ycf34 PF10718.9 EAY00567.1 - 0.2 12.4 1.5 18 6.1 0.2 3.1 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 DUF3839 PF12943.7 EAY00568.1 - 8.1e-156 516.6 11.5 1e-155 516.3 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAY00568.1 - 0.095 13.0 0.7 2 8.7 0.1 3.1 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAY00568.1 - 1.2 9.6 5.9 9.5 6.8 0.2 3.3 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY00568.1 - 1.9 8.9 6.5 12 6.3 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAY00568.1 - 5.1 7.7 6.4 0.92 10.1 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PTR PF12789.7 EAY00569.1 - 2.8e-21 75.3 6.1 1.1e-16 60.6 1.4 5.9 6 1 0 6 6 6 2 Phage tail repeat like DUF3391 PF11871.8 EAY00569.1 - 0.85 10.2 4.2 1.1 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 EAY00569.1 - 1.1 8.8 17.3 0.21 11.2 6.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4795) TMP PF05017.14 EAY00571.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY00572.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP MCM_bind PF09739.9 EAY00573.1 - 5.1e-38 130.9 7.9 9.6e-36 123.4 3.3 2.5 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Pcc1 PF09341.10 EAY00574.1 - 9.5e-09 35.3 0.0 1.1e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 ATP_bind_1 PF03029.17 EAY00574.1 - 0.027 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ThiF PF00899.21 EAY00575.1 - 4.9e-17 62.1 0.0 7.9e-17 61.4 0.0 1.6 1 1 0 1 1 1 1 ThiF family Gly_rich PF12810.7 EAY00576.1 - 2.3e-41 142.3 41.0 2.7e-41 142.1 41.0 1.0 1 0 0 1 1 1 1 Glycine rich protein OspE PF02471.17 EAY00577.1 - 0.018 15.2 0.9 0.12 12.6 0.9 2.4 1 1 0 1 1 1 0 Borrelia outer surface protein E Arm-DNA-bind_2 PF12167.8 EAY00577.1 - 0.033 14.1 1.0 0.15 12.0 0.0 2.5 2 1 1 3 3 3 0 Arm DNA-binding domain PriA_C PF18074.1 EAY00578.1 - 0.15 12.8 2.7 3.9 8.4 0.3 2.8 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Spc7 PF08317.11 EAY00578.1 - 0.22 10.4 32.6 0.28 10.0 15.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2935 PF11155.8 EAY00578.1 - 0.34 11.3 5.1 18 5.7 2.7 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) DUF5021 PF16424.5 EAY00578.1 - 0.37 10.6 3.3 0.21 11.4 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5021) DHR10 PF18595.1 EAY00578.1 - 1.9 8.5 28.9 0.13 12.3 8.0 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF3090 PF11290.8 EAY00578.1 - 6 6.6 7.7 18 5.1 7.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Ax_dynein_light PF10211.9 EAY00579.1 - 8.9e-57 192.1 5.2 1.1e-56 191.8 5.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain CCDC144C PF14915.6 EAY00579.1 - 0.00045 19.4 6.5 0.23 10.6 4.6 2.5 2 1 0 2 2 2 2 CCDC144C protein coiled-coil region ABC_tran_CTD PF16326.5 EAY00579.1 - 0.0015 18.8 12.5 0.0016 18.6 8.4 2.8 2 1 0 2 2 2 1 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 EAY00579.1 - 0.012 15.9 7.3 0.025 15.0 5.0 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SIKE PF05769.11 EAY00579.1 - 0.021 14.7 9.3 0.038 13.9 9.3 1.5 1 1 0 1 1 1 0 SIKE family KBP_C PF12309.8 EAY00579.1 - 0.045 13.3 3.0 0.071 12.6 2.8 1.4 1 1 0 1 1 1 0 KIF-1 binding protein C terminal Csm1_N PF18504.1 EAY00579.1 - 0.046 14.1 1.0 0.046 14.1 1.0 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 EAY00579.1 - 0.12 12.1 16.7 0.24 11.2 1.9 3.3 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 EAY00579.1 - 0.13 11.6 14.7 0.25 10.7 11.9 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding JAKMIP_CC3 PF16034.5 EAY00579.1 - 0.19 11.6 7.0 0.73 9.8 6.5 2.1 1 1 0 1 1 1 0 JAKMIP CC3 domain THOC7 PF05615.13 EAY00579.1 - 0.36 11.1 13.8 4.6 7.5 10.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 SlyX PF04102.12 EAY00579.1 - 0.37 11.4 4.6 4.2 8.0 2.3 3.1 2 1 0 2 2 2 0 SlyX TMCO5 PF14992.6 EAY00579.1 - 0.41 10.2 5.7 0.84 9.2 5.7 1.4 1 0 0 1 1 1 0 TMCO5 family Strep_SA_rep PF06696.11 EAY00579.1 - 0.73 9.9 5.5 11 6.2 1.3 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Jnk-SapK_ap_N PF09744.9 EAY00579.1 - 1.3 9.3 9.6 13 6.0 9.6 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EAY00579.1 - 1.4 9.5 12.7 20 5.7 10.8 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EAY00579.1 - 1.5 9.1 16.7 3.1 8.1 5.1 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1640 PF07798.11 EAY00579.1 - 1.5 8.8 10.7 4 7.5 10.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF724 PF05266.14 EAY00579.1 - 1.7 8.5 10.0 7.4 6.3 8.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ATF7IP_BD PF16788.5 EAY00579.1 - 2.4 8.2 9.9 5.4 7.1 2.4 2.5 1 1 1 2 2 2 0 ATF-interacting protein binding domain Cnn_1N PF07989.11 EAY00579.1 - 2.5 8.3 10.9 1.5 9.0 2.3 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 EAY00579.1 - 3.5 7.9 9.4 1.9 8.8 6.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 EAY00579.1 - 3.6 8.3 6.4 17 6.1 4.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 EAY00579.1 - 3.9 7.6 11.6 4.2 7.5 0.8 3.1 3 0 0 3 3 3 0 Basic region leucine zipper GrpE PF01025.19 EAY00579.1 - 4 7.1 13.0 66 3.1 11.3 2.9 2 2 0 2 2 2 0 GrpE ZapB PF06005.12 EAY00579.1 - 9.1 6.8 10.5 0.77 10.2 3.9 2.6 2 1 1 3 3 2 0 Cell division protein ZapB CLASP_N PF12348.8 EAY00580.1 - 3e-17 63.0 4.5 3e-17 63.0 4.5 2.2 2 1 0 2 2 2 1 CLASP N terminal RIX1 PF08167.12 EAY00580.1 - 0.005 16.6 5.3 1.2 8.9 1.5 3.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EAY00580.1 - 0.13 12.9 2.0 0.41 11.3 0.1 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HTH_38 PF13936.6 EAY00580.1 - 0.14 11.9 0.4 1.7 8.5 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HEAT PF02985.22 EAY00580.1 - 0.49 10.8 4.6 7.7 7.1 0.0 4.5 6 0 0 6 6 6 0 HEAT repeat PSP PF04046.16 EAY00581.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00582.1 - 0.036 14.6 4.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00583.1 - 0.025 15.1 0.8 0.055 13.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00584.1 - 4.4e-23 81.1 12.5 6.2e-17 61.4 1.4 3.6 3 1 0 3 3 3 2 Phage tail repeat like DUF240 PF03086.14 EAY00584.1 - 0.052 13.5 2.2 1 9.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) TMPIT PF07851.13 EAY00586.1 - 8.6 5.5 13.0 12 5.0 13.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 EAY00586.1 - 9.4 6.4 13.9 4.3 7.5 1.6 2.6 2 0 0 2 2 2 0 bZIP transcription factor Ribosomal_L36e PF01158.18 EAY00587.1 - 9.3e-21 73.9 2.8 1.2e-20 73.6 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EAY00587.1 - 0.051 13.4 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Thioredoxin PF00085.20 EAY00588.1 - 2.8e-12 46.5 0.9 7.4e-12 45.2 0.9 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAY00588.1 - 0.0016 18.8 0.3 0.0044 17.5 0.3 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAY00588.1 - 0.065 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Thioredoxin-like Rho_N PF07498.12 EAY00588.1 - 0.073 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF356 PF04009.12 EAY00588.1 - 0.1 12.9 0.6 0.21 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF356) Myb_DNA-binding PF00249.31 EAY00589.1 - 2.9e-32 110.6 3.9 1.8e-15 56.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00589.1 - 1.2e-21 76.7 3.2 1.1e-12 48.0 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY00589.1 - 2.9e-05 24.0 0.1 0.0042 17.1 0.0 2.3 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAY00589.1 - 0.019 14.8 0.4 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Phosphoprotein PF00922.17 EAY00589.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein SANT_DAMP1_like PF16282.5 EAY00589.1 - 0.12 12.6 1.6 0.38 11.0 0.0 2.7 3 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAY00589.1 - 0.36 11.2 8.7 2 8.9 2.5 3.3 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 EAY00590.1 - 7.4e-58 193.1 0.5 8.8e-16 58.3 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00590.1 - 5.9e-41 138.3 0.2 1.5e-11 44.6 0.0 5.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00590.1 - 3.9e-39 132.2 0.1 8.1e-09 35.6 0.0 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY00590.1 - 1.8e-36 123.0 0.0 1.1e-05 25.6 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAY00590.1 - 1e-28 96.2 0.0 0.00024 21.3 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat DUF3083 PF11281.8 EAY00590.1 - 0.0016 17.9 0.0 6.6 6.0 0.0 3.8 1 1 4 5 5 5 2 Protein of unknown function (DUF3083) EF-hand_1 PF00036.32 EAY00591.1 - 7.6e-28 94.0 13.6 9.8e-08 31.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAY00591.1 - 3.1e-27 94.8 9.9 5e-13 49.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAY00591.1 - 4.2e-22 76.1 10.6 7.9e-09 34.8 0.1 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EAY00591.1 - 2.2e-18 65.8 10.1 4.1e-08 33.0 1.6 3.9 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EAY00591.1 - 1.4e-11 43.3 15.0 1.8e-05 24.0 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 EAY00591.1 - 8.4e-07 29.2 0.7 0.016 15.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EAY00591.1 - 0.0036 17.5 3.5 0.041 14.1 1.8 2.4 2 0 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EAY00591.1 - 0.0046 17.2 4.5 0.025 14.9 2.5 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAY00591.1 - 0.021 14.8 7.1 2 8.4 3.2 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EAY00591.1 - 0.026 14.4 1.5 1.6 8.6 0.2 3.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_14 PF17959.1 EAY00591.1 - 0.029 14.7 1.8 0.33 11.3 0.7 2.6 1 1 1 2 2 2 0 EF-hand domain Csm2_III-A PF03750.13 EAY00591.1 - 0.063 14.1 0.1 0.88 10.4 0.0 2.3 2 0 0 2 2 2 0 Csm2 Type III-A CCAP PF11105.8 EAY00591.1 - 0.15 12.0 0.4 0.24 11.4 0.4 1.5 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a DUF3008 PF11450.8 EAY00591.1 - 0.15 12.2 0.1 0.75 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF1456 PF07308.13 EAY00591.1 - 0.16 12.3 1.1 20 5.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) DUF496 PF04363.12 EAY00591.1 - 0.63 10.1 4.5 1.7 8.7 1.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF496) PSP PF04046.16 EAY00593.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF1493 PF07377.12 EAY00594.1 - 0.042 14.3 0.6 0.093 13.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00595.1 - 1e-07 31.9 9.9 1e-07 31.9 9.9 4.9 5 1 1 6 6 6 2 Phage tail repeat like betaPIX_CC PF16523.5 EAY00595.1 - 0.015 15.1 0.7 3.4 7.6 0.0 3.2 2 1 0 2 2 2 0 betaPIX coiled coil DUF4116 PF13475.6 EAY00595.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF445 PF04286.12 EAY00595.1 - 0.74 9.5 5.7 1 9.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3417 PF11897.8 EAY00595.1 - 0.96 9.9 4.9 0.23 11.9 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF3839 PF12943.7 EAY00596.1 - 5e-106 353.6 6.3 5.6e-106 353.4 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAY00597.1 - 3e-25 89.1 4.5 4.3e-25 88.6 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) T5orf172 PF10544.9 EAY00598.1 - 9.8e-07 29.3 0.2 2.4e-06 28.0 0.2 1.6 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAY00598.1 - 0.017 14.6 0.3 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Pox_A32 PF04665.12 EAY00599.1 - 2.4e-07 30.4 2.8 3.5e-07 29.9 2.8 1.4 1 1 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAY00599.1 - 0.0041 16.8 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Elong_Iki1 PF10483.9 EAY00599.1 - 0.043 13.3 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IstB_IS21 PF01695.17 EAY00599.1 - 0.058 13.1 0.1 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4588 PF15251.6 EAY00599.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3783 PF12646.7 EAY00599.1 - 0.17 11.8 2.2 1.2 9.1 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) DUF2666 PF10869.8 EAY00599.1 - 0.35 11.1 8.5 5.4 7.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAY00600.1 - 5.1e-156 517.3 14.0 6.4e-156 516.9 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAY00600.1 - 0.3 11.4 2.0 0.97 9.8 0.5 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit KELK PF15796.5 EAY00600.1 - 1.3 9.6 7.5 3.5 8.2 1.3 3.0 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMP PF05017.14 EAY00602.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY00603.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP RhoGAP PF00620.27 EAY00604.1 - 5.9e-31 107.4 0.4 5.9e-31 107.4 0.4 2.2 3 0 0 3 3 3 1 RhoGAP domain PI3K_rbd PF00794.18 EAY00604.1 - 0.00014 22.0 0.0 0.00044 20.4 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF5591 PF17884.1 EAY00604.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) TCTP PF00838.17 EAY00606.1 - 4.3e-21 76.0 1.8 2.1e-20 73.7 1.8 1.8 1 1 0 1 1 1 1 Translationally controlled tumour protein 5_nucleotid_C PF02872.18 EAY00606.1 - 0.00083 19.6 0.0 0.00098 19.4 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain CENP-F_leu_zip PF10473.9 EAY00608.1 - 2.9e-06 27.3 12.5 2.9e-06 27.3 12.5 1.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 EAY00608.1 - 7.3e-05 22.3 7.8 7.3e-05 22.3 7.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) FlxA PF14282.6 EAY00608.1 - 0.0085 16.1 3.5 0.0085 16.1 3.5 2.8 2 1 1 3 3 2 2 FlxA-like protein V-ATPase_G PF03179.15 EAY00608.1 - 0.011 16.2 0.7 0.011 16.2 0.7 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit MscS_porin PF12795.7 EAY00608.1 - 0.016 14.7 15.0 0.029 13.9 15.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain LPP PF04728.13 EAY00608.1 - 0.022 15.1 2.2 0.99 9.8 0.1 2.9 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Med10 PF09748.9 EAY00608.1 - 0.041 13.9 1.9 0.85 9.6 1.9 2.6 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex LRRFIP PF09738.9 EAY00608.1 - 0.061 12.8 20.2 0.11 12.0 3.1 2.2 1 1 1 2 2 2 0 LRRFIP family Med21 PF11221.8 EAY00608.1 - 0.069 13.4 1.1 0.069 13.4 1.1 2.8 1 1 1 2 2 2 0 Subunit 21 of Mediator complex FAP206 PF12018.8 EAY00608.1 - 0.07 12.6 8.4 0.027 14.0 5.6 1.6 1 1 1 2 2 2 0 Domain of unknown function ATG16 PF08614.11 EAY00608.1 - 0.081 13.1 19.1 0.12 12.6 16.1 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EAY00608.1 - 0.19 12.0 14.5 2.1 8.6 4.5 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 EAY00608.1 - 0.22 11.7 13.5 0.39 10.8 11.0 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 EAY00608.1 - 0.28 11.3 22.3 6.1 6.9 3.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EAY00608.1 - 0.28 10.0 19.4 0.33 9.8 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IFP_35_N PF07334.13 EAY00608.1 - 0.31 11.1 16.8 0.5 10.5 1.1 2.9 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NPV_P10 PF05531.12 EAY00608.1 - 0.31 11.5 2.7 2.3 8.7 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 EAY00608.1 - 0.32 11.8 11.7 2 9.2 7.5 2.8 1 1 1 2 2 2 0 Occludin homology domain CorA PF01544.18 EAY00608.1 - 0.57 9.4 6.7 0.92 8.8 6.7 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein LapA_dom PF06305.11 EAY00608.1 - 0.59 10.0 4.4 13 5.6 1.1 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DivIC PF04977.15 EAY00608.1 - 0.7 9.7 13.3 0.15 11.8 3.7 2.8 1 1 1 2 2 2 0 Septum formation initiator Allexi_40kDa PF05549.11 EAY00608.1 - 0.77 9.2 7.9 0.28 10.6 4.8 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.11 EAY00608.1 - 0.94 9.8 4.3 4.2 7.7 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.6 EAY00608.1 - 1.3 9.5 10.7 6.1 7.4 1.3 2.8 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) GTP-bdg_M PF16360.5 EAY00608.1 - 1.6 9.3 9.9 0.35 11.5 3.0 2.9 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region BRI3BP PF14965.6 EAY00608.1 - 2 7.9 3.2 4.1 6.9 0.2 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 ZapB PF06005.12 EAY00608.1 - 2.2 8.8 25.7 0.71 10.4 6.5 3.3 1 1 2 3 3 3 0 Cell division protein ZapB BST2 PF16716.5 EAY00608.1 - 2.5 8.8 15.0 3.9 8.1 0.2 3.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Histone_HNS PF00816.21 EAY00608.1 - 4.5 8.2 8.8 1.5 9.7 4.8 2.1 1 1 1 2 2 2 0 H-NS histone family DUF4407 PF14362.6 EAY00608.1 - 4.9 6.4 12.3 6.8 6.0 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EAY00608.1 - 5.4 7.4 16.1 2.3 8.6 3.9 3.6 1 1 3 4 4 4 0 Csm1 N-terminal domain Rx_N PF18052.1 EAY00608.1 - 5.5 7.3 11.8 1.3 9.3 4.7 2.8 2 2 1 3 3 3 0 Rx N-terminal domain DUF3450 PF11932.8 EAY00608.1 - 6.2 6.0 14.7 2.4 7.4 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MCU PF04678.13 EAY00608.1 - 8.5 6.4 8.3 1.1e+02 2.8 8.3 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter LMBR1 PF04791.16 EAY00608.1 - 9.2 5.0 11.0 12 4.7 11.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PRKG1_interact PF15898.5 EAY00608.1 - 9.6 7.2 21.5 0.64 10.9 12.0 2.6 2 2 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 EAY00608.1 - 9.8 5.6 12.1 13 5.3 12.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DENN PF02141.21 EAY00609.1 - 3.4e-17 63.0 2.2 6e-15 55.7 0.2 2.7 3 0 0 3 3 3 2 DENN (AEX-3) domain dDENN PF03455.19 EAY00609.1 - 0.00071 19.5 0.3 0.0019 18.2 0.3 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 EAY00609.1 - 0.012 16.3 0.1 0.031 15.0 0.1 1.8 1 0 0 1 1 1 0 uDENN domain MULE PF10551.9 EAY00610.1 - 2e-11 44.2 0.1 3.9e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain PWI PF01480.17 EAY00610.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 PWI domain FLYWCH PF04500.16 EAY00610.1 - 0.23 11.6 4.4 0.45 10.7 4.4 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF4107 PF13389.6 EAY00611.1 - 6.2e-73 244.3 3.9 7.9e-73 244.0 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAY00612.1 - 0.009 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAY00614.1 - 7.8e-155 513.4 12.0 1e-154 513.0 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00614.1 - 3.1 8.3 5.9 4.7 7.7 0.2 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PapD_N PF00345.20 EAY00615.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAY00616.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY00616.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAY00617.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAY00618.1 - 0.056 13.4 9.2 0.092 12.7 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY00618.1 - 2.7 8.5 6.0 3.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY00619.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY00619.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF563 PF04577.14 EAY00620.1 - 1.2e-23 84.3 0.1 2.1e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3447 PF11929.8 EAY00621.1 - 2.6e-20 72.1 6.0 2.6e-20 72.1 6.0 4.0 3 2 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00621.1 - 1.3e-16 61.0 1.6 1.3e-12 48.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00621.1 - 8.5e-12 44.2 2.8 1.9e-05 24.7 0.2 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EAY00621.1 - 1.9e-11 44.3 2.3 1.1e-09 38.6 0.2 4.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00621.1 - 3.2e-08 33.7 0.2 9.4e-06 25.8 0.4 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY00621.1 - 4.9e-07 29.9 0.2 1.1e-05 25.7 0.3 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ras PF00071.22 EAY00622.1 - 1.2e-45 155.0 0.0 1.4e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY00622.1 - 2.2e-29 102.1 0.0 2.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY00622.1 - 2.8e-13 49.7 0.0 3.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAY00622.1 - 6.2e-06 25.9 0.4 8.7e-05 22.1 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAY00622.1 - 5.1e-05 22.8 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAY00622.1 - 0.00029 20.8 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAY00622.1 - 0.00033 20.7 0.0 0.00048 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EAY00622.1 - 0.00064 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EAY00622.1 - 0.018 14.5 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EAY00622.1 - 0.074 12.8 0.7 0.37 10.5 0.7 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EAY00622.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Metallophos PF00149.28 EAY00623.1 - 2.8e-30 106.4 1.0 2.8e-30 106.4 1.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAY00623.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain WAK PF08488.11 EAY00623.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Wall-associated kinase Ank_2 PF12796.7 EAY00624.1 - 1.8e-42 143.8 6.1 1.6e-20 73.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00624.1 - 1.8e-26 92.2 1.3 5.8e-11 42.7 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00624.1 - 3.9e-18 65.3 0.1 2.8e-09 37.1 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00624.1 - 4.8e-17 60.3 0.4 2e-06 27.7 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EAY00624.1 - 4.9e-15 55.2 0.4 2.5e-05 24.5 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat URO-D PF01208.17 EAY00624.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) PTR PF12789.7 EAY00627.1 - 2.1e-27 95.0 30.3 2.1e-23 82.2 7.4 5.5 5 1 0 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAY00627.1 - 0.071 12.8 0.1 0.25 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAY00627.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF240 PF03086.14 EAY00627.1 - 0.79 9.6 5.9 2.8 7.9 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Trypan_PARP PF05887.11 EAY00628.1 - 0.042 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY00629.1 - 0.034 14.6 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4108 PF13390.6 EAY00630.1 - 2.6e-60 202.5 6.9 2.9e-60 202.3 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF4106 PF13388.6 EAY00631.1 - 7.6e-122 407.5 34.4 7.6e-122 407.5 34.4 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) PAS PF00989.25 EAY00631.1 - 0.5 10.4 2.3 9.1 6.3 0.1 3.0 3 0 0 3 3 3 0 PAS fold TMEM154 PF15102.6 EAY00632.1 - 0.0018 18.2 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 EAY00632.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.11 EAY00632.1 - 0.03 14.3 1.9 0.039 13.9 1.6 1.4 1 1 0 1 1 1 0 Protocadherin T2SSF PF00482.23 EAY00632.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Herpes_gE PF02480.16 EAY00632.1 - 0.068 11.9 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ETRAMP PF09716.10 EAY00632.1 - 0.1 12.7 0.9 0.16 12.1 0.9 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4484 PF14831.6 EAY00632.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF5385 PF17359.2 EAY00633.1 - 0.00048 19.8 0.3 0.00071 19.2 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Syndecan PF01034.20 EAY00633.1 - 0.0016 18.3 0.3 0.0033 17.3 0.3 1.5 1 0 0 1 1 1 1 Syndecan domain Otopetrin PF03189.13 EAY00633.1 - 0.0029 16.5 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Otopetrin EphA2_TM PF14575.6 EAY00633.1 - 0.0032 18.3 0.1 0.0066 17.3 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 EAY00633.1 - 0.012 15.4 0.3 0.027 14.3 0.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator T4SS_CagC PF16943.5 EAY00633.1 - 0.015 15.4 0.2 0.032 14.4 0.2 1.4 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system TMEM154 PF15102.6 EAY00633.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family FeoB_associated PF12669.7 EAY00633.1 - 0.047 14.1 3.2 0.1 13.0 3.2 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5305 PF17231.2 EAY00633.1 - 0.054 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Chordopox_A13L PF05961.11 EAY00633.1 - 0.076 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SIT PF15330.6 EAY00633.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Podoplanin PF05808.11 EAY00633.1 - 1.3 9.1 6.2 2.3 8.3 6.2 1.3 1 0 0 1 1 1 0 Podoplanin Pkinase PF00069.25 EAY00634.1 - 9.1e-11 41.6 1.3 5.1e-10 39.2 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00634.1 - 2e-05 24.0 0.0 0.00078 18.8 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase IQ PF00612.27 EAY00634.1 - 0.00017 21.1 1.7 0.097 12.5 0.0 3.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif Kinase-like PF14531.6 EAY00634.1 - 0.014 14.8 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Thioredoxin PF00085.20 EAY00636.1 - 9.7e-15 54.4 0.0 1.1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EAY00636.1 - 7.7e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EAY00636.1 - 1.4e-06 28.7 0.1 3e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 EAY00636.1 - 1.6e-06 27.9 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 EAY00636.1 - 6.8e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 EAY00636.1 - 0.00011 22.3 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EAY00636.1 - 0.00028 21.1 0.2 0.0019 18.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EAY00636.1 - 0.0004 19.8 0.0 0.00045 19.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 EAY00636.1 - 0.0007 20.0 0.1 0.00098 19.5 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 EAY00636.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) L27_N PF09060.10 EAY00636.1 - 0.0073 16.3 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 L27_N T4_deiodinase PF00837.17 EAY00636.1 - 0.016 14.5 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_4 PF13462.6 EAY00636.1 - 0.038 14.2 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin UBA PF00627.31 EAY00637.1 - 9.3e-09 35.0 1.1 2.4e-08 33.7 0.1 2.4 3 0 0 3 3 3 1 UBA/TS-N domain UBA_3 PF09288.10 EAY00637.1 - 0.01 15.7 0.1 1.1 9.1 0.0 3.2 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DUF3447 PF11929.8 EAY00638.1 - 3.7e-23 81.3 19.8 7e-21 74.0 5.2 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00638.1 - 4e-15 56.0 2.1 2e-09 37.8 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00638.1 - 5.5e-15 55.7 1.0 1.1e-12 48.4 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00638.1 - 3.4e-12 45.4 2.5 1.2e-05 25.3 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAY00638.1 - 9.8e-09 35.3 0.1 7.1e-07 29.4 0.2 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY00638.1 - 3.3e-08 33.6 0.4 1.5e-05 25.2 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAY00639.1 - 1e-20 74.1 0.3 3.2e-13 50.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00639.1 - 2.6e-20 72.5 0.9 1.2e-10 41.6 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00639.1 - 3.6e-16 57.6 4.8 2.4e-05 24.3 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAY00639.1 - 8.7e-15 54.4 1.0 3.7e-06 27.1 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAY00639.1 - 8.1e-13 48.3 1.5 0.00021 21.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Tht1 PF04163.12 EAY00639.1 - 0.077 11.8 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Adeno_100 PF02438.16 EAY00639.1 - 0.18 9.9 0.2 0.26 9.4 0.2 1.2 1 0 0 1 1 1 0 Late 100kD protein DUF1664 PF07889.12 EAY00640.1 - 0.00022 21.3 63.3 0.078 13.0 1.5 6.5 3 1 4 7 7 7 5 Protein of unknown function (DUF1664) ATG16 PF08614.11 EAY00640.1 - 0.00086 19.6 94.9 0.36 11.0 23.3 4.8 1 1 2 3 3 2 2 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 EAY00640.1 - 0.0012 18.4 84.9 0.0032 17.0 24.3 4.2 1 1 3 4 4 4 2 Leucine zipper Fib_alpha PF08702.10 EAY00640.1 - 0.0031 17.7 28.6 0.0077 16.4 14.5 5.4 3 2 2 5 5 5 3 Fibrinogen alpha/beta chain family TACC_C PF05010.14 EAY00640.1 - 0.0044 16.8 20.4 0.0044 16.8 20.4 4.7 1 1 1 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 EAY00640.1 - 0.0051 17.0 8.7 0.0051 17.0 8.7 5.3 2 2 3 5 5 5 3 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 EAY00640.1 - 0.0057 16.6 4.9 0.0057 16.6 4.9 8.8 4 2 6 10 10 9 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EAY00640.1 - 0.0087 16.1 9.8 0.0087 16.1 9.8 5.8 2 2 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 EAY00640.1 - 0.0099 15.6 16.6 0.0099 15.6 16.6 5.9 2 2 4 6 6 6 3 Domain of unknown function (DUF4201) DUF3584 PF12128.8 EAY00640.1 - 0.085 10.4 79.9 0.02 12.4 55.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) KH_5 PF13184.6 EAY00640.1 - 0.18 11.9 3.9 0.55 10.4 0.5 3.3 2 1 0 2 2 2 0 NusA-like KH domain Spc7 PF08317.11 EAY00640.1 - 0.22 10.4 91.2 0.22 10.4 22.0 5.2 2 2 3 5 5 5 0 Spc7 kinetochore protein MscS_porin PF12795.7 EAY00640.1 - 0.41 10.2 92.5 1.2 8.7 31.8 3.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Matrilin_ccoil PF10393.9 EAY00640.1 - 0.8 9.6 15.3 1.3 9.0 0.6 4.8 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PspA_IM30 PF04012.12 EAY00640.1 - 3.6 7.1 74.9 1.3 8.6 2.5 6.4 1 1 4 6 6 6 0 PspA/IM30 family APG6_N PF17675.1 EAY00640.1 - 3.9 8.0 91.1 0.43 11.1 22.4 5.6 2 2 2 4 4 3 0 Apg6 coiled-coil region FUSC PF04632.12 EAY00640.1 - 4.6 5.6 23.4 1.7 7.0 6.0 3.2 2 1 1 3 3 3 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EAY00640.1 - 5 6.4 71.3 1.1 8.6 25.5 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) RVT_N PF13655.6 EAY00641.1 - 1.3 9.4 6.3 1.8 8.9 2.8 2.9 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase PI3K_P85_iSH2 PF16454.5 EAY00642.1 - 0.00014 21.5 4.4 0.00022 20.9 4.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4600 PF15372.6 EAY00642.1 - 0.0006 20.3 3.2 0.00086 19.7 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) zf-C4H2 PF10146.9 EAY00642.1 - 0.0018 18.6 3.9 0.0026 18.1 3.9 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein APG6_N PF17675.1 EAY00642.1 - 0.0067 17.0 7.0 0.0099 16.4 7.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 EAY00642.1 - 0.0083 16.3 7.5 0.013 15.7 7.5 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF2203 PF09969.9 EAY00642.1 - 0.011 16.4 1.6 0.017 15.9 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 EAY00642.1 - 0.017 15.3 3.9 0.027 14.7 3.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 EAY00642.1 - 0.018 14.7 2.3 0.022 14.4 2.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family Syntaxin-6_N PF09177.11 EAY00642.1 - 0.02 15.4 2.2 1 9.9 0.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TSC22 PF01166.18 EAY00642.1 - 0.025 14.9 4.8 0.025 14.9 4.8 1.9 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF724 PF05266.14 EAY00642.1 - 0.027 14.3 4.1 0.037 13.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3573 PF12097.8 EAY00642.1 - 0.049 12.5 4.1 0.063 12.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LPP PF04728.13 EAY00642.1 - 0.07 13.5 0.5 0.07 13.5 0.5 2.0 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DUF3287 PF11690.8 EAY00642.1 - 0.075 12.8 1.4 0.27 11.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF4140 PF13600.6 EAY00642.1 - 0.087 13.3 0.3 0.16 12.4 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3450 PF11932.8 EAY00642.1 - 0.099 11.9 4.5 0.13 11.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 EAY00642.1 - 0.16 12.4 5.3 0.67 10.4 5.3 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) P4Ha_N PF08336.11 EAY00642.1 - 0.2 11.7 7.0 0.23 11.5 5.4 1.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region BRE1 PF08647.11 EAY00642.1 - 0.21 11.7 11.9 0.38 10.9 11.7 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 EAY00642.1 - 0.23 11.9 8.2 0.5 10.8 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SIX1_SD PF16878.5 EAY00642.1 - 0.24 11.9 5.7 0.21 12.1 2.0 2.0 1 1 1 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain AKNA PF12443.8 EAY00642.1 - 0.27 11.9 3.6 0.57 10.9 3.5 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor CK_II_beta PF01214.18 EAY00642.1 - 0.28 11.0 4.2 0.12 12.2 1.8 1.7 2 0 0 2 2 2 0 Casein kinase II regulatory subunit SMC_N PF02463.19 EAY00642.1 - 0.33 10.3 5.3 0.63 9.4 3.6 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain bZIP_1 PF00170.21 EAY00642.1 - 0.43 10.7 9.2 0.15 12.2 6.4 1.7 2 0 0 2 2 1 0 bZIP transcription factor IFP_35_N PF07334.13 EAY00642.1 - 0.88 9.7 9.5 1 9.5 3.9 2.4 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NPV_P10 PF05531.12 EAY00642.1 - 0.94 10.0 6.4 2.4 8.7 6.4 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 EAY00642.1 - 2.6 7.9 9.3 2.2 8.1 5.5 2.3 1 1 1 2 2 2 0 Septum formation initiator LON_substr_bdg PF02190.16 EAY00642.1 - 3.4 7.5 8.6 3.5 7.5 0.0 2.1 1 1 1 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain Ank_2 PF12796.7 EAY00643.1 - 8.6e-44 148.0 0.3 1.8e-16 60.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00643.1 - 2e-36 123.9 0.4 3.1e-09 37.2 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00643.1 - 6.1e-32 109.3 0.0 8.8e-10 38.6 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00643.1 - 3.7e-28 96.7 0.1 0.00035 20.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 EAY00643.1 - 9.4e-23 77.8 0.1 0.0008 19.7 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat DUF3083 PF11281.8 EAY00643.1 - 0.0078 15.6 0.1 0.46 9.8 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3083) PHTB1_N PF14727.6 EAY00643.1 - 0.079 12.3 0.6 9.7 5.4 0.2 2.7 1 1 0 2 2 2 0 PTHB1 N-terminus DUF809 PF05663.11 EAY00643.1 - 5.3 7.2 8.2 15 5.7 0.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF809) KilA-N PF04383.13 EAY00644.1 - 1.9e-42 143.6 2.8 1.9e-42 143.6 2.8 2.4 2 1 0 2 2 2 1 KilA-N domain Connexin PF00029.19 EAY00644.1 - 0.024 14.4 0.3 0.024 14.4 0.3 2.0 1 1 1 2 2 2 0 Connexin DUF3213 PF11491.8 EAY00644.1 - 0.037 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) FPN1 PF06963.12 EAY00644.1 - 0.35 9.4 0.2 0.59 8.6 0.2 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3839 PF12943.7 EAY00645.1 - 6.9e-153 507.0 12.3 8.7e-153 506.7 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAY00645.1 - 0.011 16.2 0.7 0.89 10.0 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NTP_transf_6 PF06042.11 EAY00645.1 - 0.073 12.9 0.7 0.21 11.4 0.3 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase PSP PF04046.16 EAY00646.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAY00647.1 - 2.3e-19 69.8 0.0 6.5e-10 39.5 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) C2 PF00168.30 EAY00647.1 - 9e-15 54.8 0.0 2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Ank_5 PF13857.6 EAY00647.1 - 4.5e-10 39.6 0.0 0.007 16.7 0.0 5.9 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00647.1 - 2.3e-09 37.6 0.0 0.067 13.8 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY00647.1 - 5.3e-09 36.1 0.0 0.0037 17.7 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_3 PF13606.6 EAY00647.1 - 1.8e-08 34.0 0.0 0.65 10.7 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 EAY00647.1 - 0.012 15.5 7.6 0.12 12.3 2.1 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00648.1 - 3.6e-59 197.3 6.9 2.7e-19 69.5 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00648.1 - 1.5e-40 137.0 0.1 1.7e-09 38.0 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00648.1 - 5.1e-40 130.9 0.6 0.00015 21.9 0.0 8.8 7 1 1 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAY00648.1 - 5.3e-38 128.6 0.4 0.0002 21.6 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAY00648.1 - 8.4e-38 127.2 0.2 2.4e-06 27.7 0.0 8.5 7 1 1 8 8 8 7 Ankyrin repeat Clathrin PF00637.20 EAY00648.1 - 0.44 10.4 5.8 4 7.3 0.2 3.8 4 0 0 4 4 4 0 Region in Clathrin and VPS Ank_2 PF12796.7 EAY00649.1 - 2.3e-57 191.5 0.8 2.7e-13 50.3 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00649.1 - 6.3e-44 146.6 0.1 7.1e-06 26.2 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EAY00649.1 - 1.4e-40 137.1 0.2 4.1e-08 33.6 0.0 7.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00649.1 - 2.7e-33 113.6 0.1 2.8e-06 27.5 0.1 7.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00649.1 - 1.5e-31 104.8 0.3 0.0023 18.3 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat DUF4105 PF13387.6 EAY00649.1 - 0.00042 20.0 0.0 0.025 14.2 0.0 3.1 2 2 2 4 4 4 1 Domain of unknown function (DUF4105) EPSP_synthase PF00275.20 EAY00649.1 - 0.094 11.4 0.2 1.3 7.6 0.0 2.6 2 1 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ribosomal_L30 PF00327.20 EAY00649.1 - 0.93 9.4 4.6 72 3.4 0.1 4.5 6 0 0 6 6 6 0 Ribosomal protein L30p/L7e DUF4108 PF13390.6 EAY00651.1 - 2.5e-60 202.5 8.3 2.8e-60 202.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Antimicrobial_7 PF08102.11 EAY00651.1 - 0.11 12.8 0.1 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Pox_D5 PF03288.16 EAY00652.1 - 5.4e-05 23.6 2.9 0.00027 21.4 2.9 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like RFX_DNA_binding PF02257.15 EAY00652.1 - 0.046 14.4 0.1 0.093 13.4 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Cdc6_C PF09079.11 EAY00652.1 - 0.055 13.4 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain ATP_bind_1 PF03029.17 EAY00653.1 - 7.3e-61 206.0 0.2 8.3e-61 205.8 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 EAY00653.1 - 9.6e-05 22.4 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAY00653.1 - 0.00022 21.7 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAY00653.1 - 0.00031 20.5 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAY00653.1 - 0.00092 19.0 0.0 0.0019 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAY00653.1 - 0.00093 19.6 0.0 0.0018 18.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAY00653.1 - 0.0031 17.8 0.0 0.012 15.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EAY00653.1 - 0.004 17.2 0.0 0.04 14.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAY00653.1 - 0.0048 17.3 0.0 0.0071 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 EAY00653.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region cobW PF02492.19 EAY00653.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAY00653.1 - 0.026 14.1 0.1 0.29 10.6 0.0 2.4 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_28 PF13521.6 EAY00653.1 - 0.026 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EAY00653.1 - 0.032 13.8 0.0 0.32 10.5 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EAY00653.1 - 0.035 13.8 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EAY00653.1 - 0.084 12.7 0.0 0.57 10.0 0.0 2.1 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 EAY00653.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EAY00653.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 EAY00653.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EAY00653.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EAY00653.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EAY00653.1 - 0.19 11.9 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAY00653.1 - 0.19 11.0 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EAY00653.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TLD PF07534.16 EAY00654.1 - 1.6e-25 89.9 0.0 3.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 TLD zf-B_box PF00643.24 EAY00654.1 - 1.2e-16 60.6 16.6 2.4e-08 34.0 3.0 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 EAY00654.1 - 0.038 13.6 0.2 0.57 9.7 0.0 2.8 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase catalytic domain UPF0147 PF03685.13 EAY00654.1 - 0.4 10.8 2.3 0.45 10.6 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) tRNA-synt_2b PF00587.25 EAY00655.1 - 3.3e-36 124.9 0.0 7.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAY00655.1 - 5.9e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EAY00655.1 - 2.8e-05 24.1 0.0 5.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Fic PF02661.18 EAY00657.1 - 0.0035 18.2 0.1 1.3 10.0 0.0 2.8 2 0 0 2 2 2 2 Fic/DOC family EF-hand_10 PF14788.6 EAY00657.1 - 0.015 15.2 0.8 0.061 13.2 0.1 2.4 2 0 0 2 2 2 0 EF hand 2_5_RNA_ligase2 PF13563.6 EAY00657.1 - 0.084 12.8 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Zn_ribbon_2 PF12674.7 EAY00657.1 - 0.23 12.1 3.6 2.7 8.7 0.0 3.7 3 1 1 4 4 4 0 Putative zinc ribbon domain YmgB PF10798.8 EAY00658.1 - 0.01 15.6 0.2 0.02 14.7 0.2 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF4108 PF13390.6 EAY00658.1 - 0.51 10.3 8.6 3.6 7.5 8.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4108) DUF2666 PF10869.8 EAY00659.1 - 0.048 13.9 1.8 0.096 12.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF3839 PF12943.7 EAY00660.1 - 5.3e-153 507.4 11.3 6.8e-153 507.0 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00660.1 - 0.035 14.6 7.1 0.29 11.6 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 EAY00660.1 - 0.043 14.3 1.2 0.29 11.5 0.2 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAY00660.1 - 0.11 12.3 1.3 0.4 10.5 0.2 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase DUF2408 PF10303.9 EAY00660.1 - 1.9 9.1 6.3 1.1 9.8 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4107 PF13389.6 EAY00664.1 - 1e-50 172.1 1.0 1.2e-50 171.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2890 PF11081.8 EAY00665.1 - 0.13 12.4 0.1 0.14 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ANAPC10 PF03256.16 EAY00666.1 - 8e-27 94.1 0.0 1.1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EAY00666.1 - 8.7e-07 29.1 0.1 1.1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 EAY00666.1 - 0.0082 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain ANAPC4_WD40 PF12894.7 EAY00667.1 - 3.3e-05 24.1 0.2 0.012 16.0 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EAY00667.1 - 0.00016 20.9 6.9 0.03 13.4 0.6 5.1 4 1 2 6 6 6 2 Coatomer WD associated region WD40 PF00400.32 EAY00667.1 - 0.00045 21.0 9.1 0.032 15.1 0.5 6.0 4 2 2 6 6 6 1 WD domain, G-beta repeat WD40_3 PF15911.5 EAY00667.1 - 0.00052 20.0 0.0 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat YmzC PF14157.6 EAY00667.1 - 0.029 14.5 0.3 0.091 12.9 0.3 1.8 1 0 0 1 1 1 0 YmzC-like protein zf-UDP PF14569.6 EAY00667.1 - 0.078 13.1 3.9 1.6 8.9 1.1 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger Rad50_zn_hook PF04423.14 EAY00667.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Clathrin PF00637.20 EAY00667.1 - 1.6 8.6 6.3 1.3 8.8 0.5 3.3 3 1 1 4 4 4 0 Region in Clathrin and VPS MFS_1 PF07690.16 EAY00668.1 - 3.8e-07 29.3 5.5 9.3e-06 24.8 3.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Spt20 PF12090.8 EAY00670.1 - 2.8e-18 66.4 0.0 2.2e-15 57.0 0.0 2.3 1 1 1 2 2 2 2 Spt20 family WD40 PF00400.32 EAY00671.1 - 6.7e-14 52.1 0.1 0.003 18.4 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY00671.1 - 1.4e-10 41.3 0.0 0.047 14.0 0.0 4.8 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EAY00671.1 - 0.0021 16.9 0.2 0.6 8.8 0.0 2.7 2 1 1 3 3 3 2 Nup133 N terminal like BING4CT PF08149.11 EAY00671.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 BING4CT (NUC141) domain FXMRP1_C_core PF12235.8 EAY00671.1 - 0.024 15.3 3.1 0.038 14.6 3.1 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Nup160 PF11715.8 EAY00671.1 - 0.051 12.2 0.0 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 AT_hook PF02178.19 EAY00671.1 - 0.068 13.1 12.0 0.49 10.4 1.1 2.6 2 0 0 2 2 2 0 AT hook motif Nbas_N PF15492.6 EAY00671.1 - 0.089 12.1 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Tristanin_u2 PF16638.5 EAY00671.1 - 0.76 10.6 3.8 2 9.2 3.8 1.7 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Ank_2 PF12796.7 EAY00672.1 - 6.3e-28 97.2 2.1 3.5e-11 43.5 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00672.1 - 4.3e-23 81.1 0.1 5e-10 39.4 0.0 5.5 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00672.1 - 2e-21 73.8 2.4 9e-06 25.7 0.0 7.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 EAY00672.1 - 8e-20 70.9 0.2 0.00064 20.2 0.0 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY00672.1 - 1.1e-17 63.6 1.3 1e-07 32.1 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 EAY00672.1 - 0.0069 16.3 15.9 0.0088 16.0 0.1 4.1 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) CppA_N PF14506.6 EAY00672.1 - 0.0072 16.4 0.8 0.016 15.3 0.1 2.0 2 1 0 2 2 2 1 CppA N-terminal PPR_2 PF13041.6 EAY00672.1 - 0.065 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family TPR_1 PF00515.28 EAY00674.1 - 1.2e-14 53.4 0.1 0.00026 20.7 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAY00674.1 - 2.3e-14 52.3 0.3 0.0003 20.7 0.7 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAY00674.1 - 1.8e-09 37.0 1.4 0.0032 17.5 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAY00674.1 - 1.2e-08 35.1 0.2 0.0013 19.0 0.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAY00674.1 - 2.5e-08 33.4 0.2 0.11 12.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAY00674.1 - 1.8e-07 31.4 0.4 0.011 16.5 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAY00674.1 - 2.3e-07 31.2 0.5 0.0011 19.5 0.0 4.3 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAY00674.1 - 3.3e-06 27.6 0.0 3.3e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAY00674.1 - 4.8e-06 26.6 0.1 0.35 11.3 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAY00674.1 - 4.4e-05 23.1 0.5 0.031 13.9 0.0 4.1 2 1 2 4 4 4 1 TPR repeat Coatomer_E PF04733.14 EAY00674.1 - 8.4e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EAY00674.1 - 0.0004 20.5 0.1 0.098 12.9 1.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EAY00674.1 - 0.0019 18.3 0.0 0.008 16.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAY00674.1 - 0.0044 17.6 1.4 13 6.6 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EAY00674.1 - 0.061 13.4 4.8 2.9 8.0 2.6 3.1 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 EAY00674.1 - 0.19 11.6 2.6 39 4.3 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat FeoB_Cyto PF17910.1 EAY00674.1 - 0.73 10.4 9.4 0.12 12.9 0.3 4.1 4 0 0 4 4 4 0 FeoB cytosolic helical domain HEPN_Apea PF18739.1 EAY00674.1 - 5.2 7.6 5.9 4.1 7.9 0.2 3.3 3 1 0 3 3 3 0 Apea-like HEPN Ank_4 PF13637.6 EAY00675.1 - 1.2e-16 60.8 0.4 6.1e-09 36.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00675.1 - 2.9e-15 56.6 0.1 3.3e-10 40.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00675.1 - 3.2e-11 43.3 0.1 0.0012 19.1 0.1 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY00675.1 - 1.1e-10 41.5 0.9 0.086 13.3 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAY00675.1 - 8.4e-09 35.0 1.4 0.31 11.7 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat T2SSM_b PF10741.9 EAY00675.1 - 0.032 14.0 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF3447 PF11929.8 EAY00676.1 - 1.3e-06 28.3 2.2 1.3e-06 28.3 2.2 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00676.1 - 2e-06 28.3 0.2 0.0056 17.3 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00676.1 - 1.3e-05 25.7 0.3 0.4 11.3 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00676.1 - 0.006 17.0 0.2 1.3 9.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat TryThrA_C PF12319.8 EAY00676.1 - 0.079 12.4 0.9 0.15 11.5 0.2 1.8 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF3839 PF12943.7 EAY00677.1 - 7.2e-150 497.1 13.8 9e-150 496.8 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1493 PF07377.12 EAY00678.1 - 0.038 14.5 0.5 0.09 13.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY00679.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY00680.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Annexin PF00191.20 EAY00681.1 - 1.8 8.7 4.7 1.7 8.8 0.2 3.1 3 1 0 3 3 3 0 Annexin ABC_membrane PF00664.23 EAY00682.1 - 2.2e-37 129.2 18.5 3.2e-37 128.7 18.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAY00682.1 - 1.2e-34 119.7 0.0 2.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAY00682.1 - 2.1e-08 33.9 0.9 3.5e-06 26.6 0.1 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAY00682.1 - 9.9e-05 22.3 0.0 0.52 10.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAY00682.1 - 0.00087 19.6 0.1 0.0045 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAY00682.1 - 0.0013 18.5 0.4 0.0013 18.5 0.4 1.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAY00682.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EAY00682.1 - 0.0031 17.9 0.1 0.015 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAY00682.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EAY00682.1 - 0.02 15.4 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EAY00682.1 - 0.039 12.8 0.3 0.065 12.0 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 EAY00682.1 - 0.05 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 EAY00682.1 - 0.053 13.5 0.1 0.55 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EAY00682.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 EAY00682.1 - 0.066 12.9 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF4094 PF13334.6 EAY00682.1 - 0.086 13.3 0.0 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Tmpp129 PF10272.9 EAY00682.1 - 0.88 8.8 4.6 1.6 7.9 4.6 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor Phospholip_B PF04916.13 EAY00683.1 - 2.8e-130 435.4 8.2 3.6e-130 435.1 8.2 1.1 1 0 0 1 1 1 1 Phospholipase B PSI PF01437.25 EAY00683.1 - 0.19 12.3 5.0 0.42 11.2 5.0 1.5 1 0 0 1 1 1 0 Plexin repeat Tetraspanin PF00335.20 EAY00684.1 - 0.13 11.9 24.6 1.6 8.4 24.6 2.1 1 1 0 1 1 1 0 Tetraspanin family PalH PF08733.10 EAY00684.1 - 1.2 8.1 18.4 1.9 7.4 18.4 1.2 1 0 0 1 1 1 0 PalH/RIM21 DUF2070 PF09843.9 EAY00684.1 - 4.9 5.3 23.5 6.1 5.0 23.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PHM7_cyt PF14703.6 EAY00685.1 - 0.05 13.8 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Trimer_CC PF08954.11 EAY00685.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif Beach PF02138.18 EAY00686.1 - 6.7e-98 327.5 0.6 1.3e-97 326.4 0.6 1.6 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EAY00686.1 - 2.2e-11 43.5 3.8 2.2e-11 43.5 3.8 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EAY00686.1 - 0.001 19.1 0.4 0.0061 16.6 0.4 2.4 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EAY00686.1 - 0.32 11.9 10.2 2.9 8.9 0.5 5.0 3 1 1 4 4 4 0 WD domain, G-beta repeat SR-25 PF10500.9 EAY00687.1 - 0.0015 18.2 3.2 0.002 17.8 3.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MFMR_assoc PF16596.5 EAY00687.1 - 0.0027 18.2 3.8 0.0048 17.3 3.8 1.3 1 0 0 1 1 1 1 Disordered region downstream of MFMR YL1 PF05764.13 EAY00687.1 - 0.0038 17.4 0.2 0.0046 17.1 0.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EAY00687.1 - 0.02 13.2 1.1 0.024 12.9 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EAY00687.1 - 0.049 13.0 7.7 0.068 12.5 7.7 1.2 1 0 0 1 1 1 0 BUD22 RP-C_C PF11800.8 EAY00687.1 - 0.21 11.7 0.7 0.3 11.1 0.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CDC45 PF02724.14 EAY00687.1 - 0.31 9.3 2.1 0.38 9.0 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EAY00687.1 - 1 8.1 5.3 1.4 7.6 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.7 EAY00687.1 - 1.3 8.8 6.0 2.9 7.7 1.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein RAP1 PF07218.11 EAY00687.1 - 1.4 7.1 5.4 1.8 6.7 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 EAY00687.1 - 2.7 7.6 5.2 4.9 6.8 5.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FANCI_S2 PF14676.6 EAY00688.1 - 0.1 12.9 3.3 12 6.2 0.3 3.3 3 1 0 3 3 3 0 FANCI solenoid 2 DUF720 PF05302.11 EAY00688.1 - 0.15 11.9 2.2 0.31 10.9 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) GHL13 PF14883.6 EAY00688.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 U3_assoc_6 PF08640.11 EAY00688.1 - 0.37 10.9 2.6 0.61 10.2 1.2 2.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TPR_16 PF13432.6 EAY00689.1 - 9.3e-10 39.0 0.3 0.075 13.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAY00689.1 - 3.2e-06 26.8 9.6 0.056 13.6 1.3 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAY00689.1 - 0.00013 22.5 1.7 0.31 12.0 0.2 4.6 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAY00689.1 - 0.00039 20.6 0.3 0.0021 18.3 0.3 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.8 EAY00689.1 - 0.00073 18.6 0.1 0.002 17.2 0.1 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 EAY00689.1 - 0.0024 17.6 14.3 0.043 13.6 2.9 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAY00689.1 - 0.0033 17.1 6.3 0.0098 15.6 0.1 4.1 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.6 EAY00689.1 - 0.0046 17.2 2.0 1.4 9.3 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAY00689.1 - 0.014 15.5 0.1 0.88 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAY00689.1 - 0.027 14.5 1.7 5.6 7.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AhpC-TSA_2 PF13911.6 EAY00689.1 - 0.1 12.7 0.1 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme TPR_19 PF14559.6 EAY00689.1 - 0.22 12.0 5.2 1.2 9.7 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2115 PF09888.9 EAY00689.1 - 0.33 11.5 2.6 0.95 10.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) MIT PF04212.18 EAY00689.1 - 0.61 10.2 6.5 5 7.3 0.0 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EAY00689.1 - 1.2 9.6 11.9 0.076 13.3 1.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat ATP_transf PF09830.9 EAY00690.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Ribosomal_L27e PF01777.18 EAY00691.1 - 2.3e-21 75.9 6.9 3.1e-21 75.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAY00691.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif RNA_pol_Rpb1_5 PF04998.17 EAY00691.1 - 0.14 11.5 0.1 0.16 11.4 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HSP70 PF00012.20 EAY00693.1 - 1.1e-28 99.9 7.5 3.2e-27 95.0 0.8 2.9 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAY00693.1 - 0.00041 19.3 0.1 0.0011 17.9 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein SAM_KSR1 PF13543.6 EAY00693.1 - 0.041 14.0 0.9 0.11 12.7 0.9 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF1986 PF09342.11 EAY00693.1 - 0.086 13.2 0.1 4.5 7.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) FtsA PF14450.6 EAY00693.1 - 0.17 12.3 1.8 0.55 10.7 1.1 2.6 3 1 0 3 3 3 0 Cell division protein FtsA NOD PF06816.13 EAY00694.1 - 0.035 13.7 0.3 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 NOTCH protein Ribosomal_L4 PF00573.22 EAY00695.1 - 1.6e-42 145.4 0.7 2.2e-42 144.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EAY00695.1 - 1.5e-08 34.6 0.1 6.1e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain UPF0182 PF03699.13 EAY00696.1 - 6.1 4.8 10.5 0.13 10.4 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0182) UCH PF00443.29 EAY00697.1 - 4e-38 131.4 0.0 8.3e-38 130.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAY00697.1 - 1.7e-10 41.3 1.1 1.7e-10 41.3 1.1 3.8 4 1 0 4 4 4 1 DUSP domain UCH_1 PF13423.6 EAY00697.1 - 1.8e-08 34.3 16.3 2.9e-05 23.8 16.3 3.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TfuA PF07812.12 EAY00697.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 TfuA-like protein PDR_assoc PF08370.11 EAY00698.1 - 0.27 11.0 4.2 0.73 9.6 4.2 1.7 1 0 0 1 1 1 0 Plant PDR ABC transporter associated EGF_3 PF12947.7 EAY00698.1 - 1.1 9.5 18.8 0.057 13.6 11.8 2.3 2 0 0 2 2 2 0 EGF domain EGF_MSP1_1 PF12946.7 EAY00698.1 - 1.6 8.9 10.1 6.8 6.8 9.7 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF PF00008.27 EAY00698.1 - 3 8.2 15.4 0.24 11.7 9.1 2.4 3 0 0 3 3 3 0 EGF-like domain Peptidase_M60 PF13402.6 EAY00699.1 - 2.2e-74 250.4 0.6 5.7e-74 249.0 0.2 1.9 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 EAY00699.1 - 2.5e-28 98.2 0.1 6.8e-28 96.7 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 EAY00699.1 - 0.0095 15.8 0.2 0.034 14.0 0.2 1.9 1 0 0 1 1 1 1 PA14 domain ETRAMP PF09716.10 EAY00699.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Syndecan PF01034.20 EAY00700.1 - 0.12 12.3 2.8 0.23 11.4 2.8 1.4 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 EAY00700.1 - 1.3 9.3 0.0 1.3 9.3 0.0 6.7 2 1 0 2 2 2 0 Orf78 (ac78) Mucin-like PF16058.5 EAY00700.1 - 9.3 6.4 227.7 4.9 7.3 57.1 5.2 1 1 3 4 4 4 0 Mucin-like Ank_2 PF12796.7 EAY00701.1 - 2.4e-25 88.9 3.8 3e-09 37.3 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00701.1 - 1.5e-22 79.7 2.9 8.9e-09 35.7 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00701.1 - 2.2e-18 64.4 6.8 2.7e-05 24.2 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAY00701.1 - 3.9e-16 58.9 2.6 7.2e-07 29.4 0.0 5.4 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00701.1 - 1.9e-12 47.1 0.1 0.00039 20.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Mucin_bdg PF03272.13 EAY00701.1 - 0.13 12.2 0.6 0.57 10.2 0.1 2.1 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module TMP PF05017.14 EAY00702.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00703.1 - 0.023 15.2 0.6 0.047 14.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00704.1 - 8.1e-13 48.2 13.6 8.1e-13 48.2 13.6 5.1 5 1 1 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAY00704.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1223 PF06764.11 EAY00704.1 - 0.68 9.9 4.6 2.4 8.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) DUF3839 PF12943.7 EAY00705.1 - 1.1e-129 431.1 8.1 1.2e-129 430.9 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00705.1 - 0.13 12.7 2.1 0.79 10.2 0.6 2.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAY00706.1 - 3.9e-06 26.7 0.2 3.9e-06 26.7 0.2 2.3 2 1 1 3 3 3 1 KilA-N domain DUF3213 PF11491.8 EAY00706.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) KIP1 PF07765.12 EAY00706.1 - 1.2 9.3 7.3 9.7 6.4 0.6 2.4 1 1 1 2 2 2 0 KIP1-like protein Pox_A32 PF04665.12 EAY00707.1 - 5.3e-07 29.3 2.3 5.3e-07 29.3 2.3 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00707.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY00707.1 - 4.3e-05 23.3 0.3 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY00707.1 - 0.00014 21.9 3.1 0.0003 20.8 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00707.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00707.1 - 0.0016 18.3 0.7 0.0031 17.3 0.7 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00707.1 - 0.0018 17.9 0.4 0.013 15.2 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00707.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAY00707.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00707.1 - 0.09 13.2 0.1 0.75 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAY00707.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY00707.1 - 0.38 11.0 4.0 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF4108 PF13390.6 EAY00709.1 - 1.3e-62 209.9 6.0 1.5e-62 209.8 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) UQ_con PF00179.26 EAY00712.1 - 4.2e-52 175.5 0.1 4.8e-52 175.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAY00712.1 - 9.4e-06 25.4 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAY00712.1 - 0.00098 19.4 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain PatG_D PF18047.1 EAY00713.1 - 3.9 7.9 5.4 4.1 7.9 2.7 2.4 2 1 0 2 2 2 0 PatG Domain DDE_1 PF03184.19 EAY00715.1 - 1.9e-13 50.4 0.0 3.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Spo0A_C PF08769.11 EAY00716.1 - 0.035 14.2 0.4 0.11 12.6 0.2 1.8 1 1 1 2 2 2 0 Sporulation initiation factor Spo0A C terminal GerE PF00196.19 EAY00716.1 - 0.13 11.9 0.3 0.97 9.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF3839 PF12943.7 EAY00718.1 - 3e-158 524.6 13.8 3.7e-158 524.3 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00718.1 - 0.58 10.7 5.4 2 8.9 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAY00720.1 - 3.3e-39 132.8 16.8 1.8e-23 82.3 7.3 5.0 5 1 0 5 5 5 2 Phage tail repeat like Herpes_IE2_3 PF03361.14 EAY00721.1 - 0.0092 15.9 1.0 0.3 10.9 0.2 2.2 2 0 0 2 2 2 2 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAY00721.1 - 0.013 15.8 3.8 0.99 9.7 0.8 2.6 2 0 0 2 2 2 0 PPP5 TPR repeat region PRA-PH PF01503.17 EAY00722.1 - 0.21 12.1 1.8 2 8.9 2.8 1.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase PTR PF12789.7 EAY00724.1 - 3.3e-16 59.1 2.5 3.3e-16 59.1 2.5 5.4 6 2 0 6 6 6 1 Phage tail repeat like DUF4116 PF13475.6 EAY00724.1 - 0.064 13.0 0.5 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3391 PF11871.8 EAY00724.1 - 0.14 12.7 2.7 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF1493 PF07377.12 EAY00725.1 - 0.021 15.3 0.5 0.045 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY00726.1 - 0.031 14.8 3.4 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY00727.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Rad9 PF04139.13 EAY00728.1 - 8.2e-16 58.2 9.0 1e-15 57.9 9.0 1.1 1 0 0 1 1 1 1 Rad9 DUF5611 PF18446.1 EAY00728.1 - 0.27 12.1 1.6 0.52 11.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5611) SHIPPO-rpt PF07004.12 EAY00729.1 - 1.4e-09 38.4 50.6 0.014 16.3 0.3 10.1 9 2 0 9 9 9 6 Sperm-tail PG-rich repeat Myb_DNA-bind_6 PF13921.6 EAY00730.1 - 5.6e-19 68.1 2.7 2.6e-14 53.2 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAY00730.1 - 6.4e-19 67.9 0.2 1.5e-08 34.7 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY00730.1 - 0.04 13.8 0.2 0.31 10.9 0.0 2.1 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAY00730.1 - 0.12 12.8 0.6 0.37 11.2 0.3 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CENP-T_C PF15511.6 EAY00732.1 - 1.5e-10 41.1 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAY00732.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAY00732.1 - 5.8e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAY00732.1 - 0.00022 21.5 0.2 0.00025 21.4 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAY00732.1 - 0.00092 19.6 0.2 0.0015 18.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAY00732.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAY00732.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAY00732.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EAY00733.1 - 1.1e-48 164.8 1.2 1.3e-48 164.7 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAY00733.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAY00733.1 - 0.00019 22.0 1.6 0.00024 21.7 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EAY00733.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein RabGAP-TBC PF00566.18 EAY00734.1 - 1.5e-29 103.2 6.9 3.4e-29 102.0 6.9 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5457 PF17540.2 EAY00734.1 - 0.099 12.8 1.7 4.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5457) CDtoxinA PF03498.14 EAY00734.1 - 0.13 11.8 1.4 0.25 10.9 1.4 1.5 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain PSP PF04046.16 EAY00738.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Steroid_dh PF02544.16 EAY00739.1 - 1.1e-38 132.6 4.7 1.1e-38 132.6 4.7 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EAY00739.1 - 4.7e-07 29.6 0.5 4.7e-07 29.6 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EAY00739.1 - 0.00073 19.9 0.4 0.00073 19.9 0.4 2.8 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EAY00739.1 - 1.7 9.1 8.5 0.14 12.6 0.4 2.6 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Gly_rich PF12810.7 EAY00740.1 - 1.8e-20 73.9 20.9 2.3e-20 73.6 20.9 1.0 1 0 0 1 1 1 1 Glycine rich protein Ank_2 PF12796.7 EAY00741.1 - 5.8e-28 97.3 5.6 2.9e-16 59.8 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00741.1 - 6.5e-22 77.3 4.7 9.7e-12 44.9 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00741.1 - 6.4e-21 74.5 8.0 4.7e-11 43.0 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY00741.1 - 3.3e-19 68.4 10.0 2e-06 28.0 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAY00741.1 - 1.8e-15 55.5 2.9 0.00053 20.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Adeno_hexon_C PF03678.14 EAY00741.1 - 0.016 14.7 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain POR_N PF01855.19 EAY00742.1 - 5.5e-63 212.8 0.1 8.6e-63 212.2 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EAY00742.1 - 2.9e-26 92.6 0.0 6.1e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 EAY00742.1 - 1.4e-10 41.1 0.1 5.6e-10 39.2 0.1 2.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 EAY00742.1 - 2.7e-09 37.5 11.0 4.6e-05 23.9 3.5 3.2 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAY00742.1 - 2e-08 34.3 4.0 7.5e-08 32.4 4.0 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EAY00742.1 - 2.5e-08 33.4 16.6 3.3e-05 23.5 2.7 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EAY00742.1 - 2.7e-08 34.6 4.5 0.0016 19.4 0.9 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain EKR PF10371.9 EAY00742.1 - 6.4e-07 29.1 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function PFOR_II PF17147.4 EAY00742.1 - 1.3e-06 28.6 0.0 3.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_6 PF12837.7 EAY00742.1 - 2.6e-06 27.2 16.3 0.00099 19.1 2.6 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EAY00742.1 - 4.1e-06 26.8 9.9 0.018 15.2 0.2 3.1 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EAY00742.1 - 1.3e-05 25.2 15.3 5.3e-05 23.3 11.6 3.4 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAY00742.1 - 0.00067 20.0 11.4 0.00077 19.9 8.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EAY00742.1 - 0.0011 19.4 10.0 0.0069 16.9 9.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAY00742.1 - 0.017 15.6 9.8 0.42 11.2 1.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 EAY00742.1 - 0.021 14.9 18.1 0.16 12.1 3.2 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EAY00742.1 - 0.053 13.7 7.1 0.089 13.0 5.3 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EAY00742.1 - 0.12 13.3 4.6 5.6 7.9 0.7 3.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EAY00742.1 - 0.51 10.9 13.3 1.4 9.6 3.8 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I RFX_DNA_binding PF02257.15 EAY00743.1 - 6.6e-05 23.5 0.2 9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EAY00743.1 - 0.00073 20.0 2.0 0.0011 19.4 2.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 EAY00743.1 - 0.013 15.5 1.3 0.018 15.0 0.2 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Pox_A32 PF04665.12 EAY00745.1 - 6.6e-07 29.0 2.7 6.6e-07 29.0 2.7 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00745.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY00745.1 - 4.3e-05 23.3 0.3 0.33 10.7 0.1 2.7 1 1 2 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY00745.1 - 0.00014 21.9 3.1 0.00034 20.6 3.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00745.1 - 0.00053 19.8 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00745.1 - 0.0016 18.3 0.8 0.0032 17.3 0.8 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00745.1 - 0.002 17.8 0.5 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00745.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAY00745.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00745.1 - 0.09 13.2 0.1 0.74 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAY00745.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY00745.1 - 0.42 10.9 4.2 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) KilA-N PF04383.13 EAY00746.1 - 4.5e-31 107.0 0.4 1.1e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAY00747.1 - 3.3e-157 521.1 11.5 4.2e-157 520.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Tup_N PF08581.10 EAY00747.1 - 0.075 13.3 1.7 9.2 6.7 0.1 3.7 3 1 0 3 3 3 0 Tup N-terminal KELK PF15796.5 EAY00747.1 - 0.088 13.3 4.6 2.1 8.9 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAY00750.1 - 2.3e-58 194.1 34.2 1.4e-33 114.7 16.0 4.6 2 2 3 5 5 5 2 Phage tail repeat like DUF4116 PF13475.6 EAY00750.1 - 0.09 12.5 1.2 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) HS1_rep PF02218.15 EAY00750.1 - 0.12 12.7 0.1 30 5.0 0.0 3.0 3 0 0 3 3 3 0 Repeat in HS1/Cortactin PH_TFIIH PF08567.11 EAY00750.1 - 0.54 10.6 3.6 20 5.6 0.2 3.3 1 1 2 3 3 3 0 TFIIH p62 subunit, N-terminal domain DUF4404 PF14357.6 EAY00750.1 - 1.4 9.6 5.5 9.1 7.0 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) PSP PF04046.16 EAY00752.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TPK_catalytic PF04263.16 EAY00753.1 - 5.9e-27 94.1 0.1 8.1e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EAY00753.1 - 2.6e-16 59.1 0.0 4.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Mur_ligase_C PF02875.21 EAY00753.1 - 0.0042 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Cullin PF00888.22 EAY00754.1 - 5.7e-54 183.8 28.5 1.7e-53 182.2 28.5 1.7 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAY00754.1 - 2.6e-05 24.2 2.0 2.6e-05 24.2 2.0 3.5 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_5 PF01022.20 EAY00754.1 - 0.0048 16.7 0.2 0.027 14.3 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF4248 PF14053.6 EAY00754.1 - 0.056 13.5 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF5484 PF17583.2 EAY00754.1 - 0.17 11.6 0.5 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5484) T3RM_EcoP15I_C PF18273.1 EAY00754.1 - 8.5 6.8 9.5 0.64 10.4 0.5 3.4 3 1 1 4 4 4 0 Type III R-M EcoP15I C-terminal domain Gly_rich PF12810.7 EAY00756.1 - 1.7e-11 44.5 26.1 2e-11 44.3 26.1 1.1 1 0 0 1 1 1 1 Glycine rich protein IspA PF04279.15 EAY00757.1 - 0.027 14.6 6.6 0.027 14.6 6.6 2.0 1 1 1 2 2 2 0 Intracellular septation protein A ABC2_membrane PF01061.24 EAY00757.1 - 0.78 9.1 11.8 0.078 12.4 2.7 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF2179 PF10035.9 EAY00757.1 - 0.8 9.5 0.0 0.8 9.5 0.0 2.5 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2179) Lipase_3 PF01764.25 EAY00758.1 - 9e-07 28.9 0.2 3.4e-06 27.0 0.1 2.1 2 1 0 2 2 2 1 Lipase (class 3) Endomucin PF07010.12 EAY00759.1 - 0.0081 16.2 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Endomucin TMEM154 PF15102.6 EAY00759.1 - 0.094 12.6 0.6 0.55 10.1 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF2615 PF11027.8 EAY00759.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Insulin_TMD PF17870.1 EAY00759.1 - 1.2 9.3 6.8 0.34 11.0 3.4 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DHHC PF01529.20 EAY00760.1 - 2.1e-22 79.6 9.5 2.1e-22 79.6 9.5 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase GIY-YIG PF01541.24 EAY00761.1 - 1.4e-13 50.9 0.0 4.1e-13 49.4 0.0 1.7 1 1 1 2 2 2 1 GIY-YIG catalytic domain Prok-RING_1 PF14446.6 EAY00761.1 - 6.6e-05 22.8 0.4 6.6e-05 22.8 0.4 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 PHD PF00628.29 EAY00761.1 - 0.00013 21.8 2.3 0.00013 21.8 2.3 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EAY00761.1 - 0.0033 17.3 1.8 0.019 14.9 0.1 2.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Mu-like_Com PF10122.9 EAY00761.1 - 0.0034 16.8 0.2 0.0089 15.5 0.2 1.6 1 0 0 1 1 1 1 Mu-like prophage protein Com T5orf172 PF10544.9 EAY00761.1 - 0.004 17.7 0.0 0.007 16.9 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain ADK_lid PF05191.14 EAY00761.1 - 0.049 13.6 4.3 5.7 7.0 0.2 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid MUG113 PF13455.6 EAY00761.1 - 0.096 13.4 0.0 0.15 12.7 0.0 1.5 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 zf-RING_9 PF13901.6 EAY00761.1 - 0.15 12.0 3.4 0.19 11.7 1.4 1.9 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DZR PF12773.7 EAY00761.1 - 0.16 12.0 6.9 12 6.0 7.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon YacG PF03884.14 EAY00761.1 - 3 7.7 8.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_2 PF13639.6 EAY00761.1 - 3 8.3 12.3 0.22 11.9 6.1 2.3 2 0 0 2 2 2 0 Ring finger domain zf-ribbon_3 PF13248.6 EAY00761.1 - 3.6 7.1 13.3 9 5.9 0.2 3.7 3 1 0 3 3 3 0 zinc-ribbon domain Cys_rich_KTR PF14205.6 EAY00761.1 - 4.3 7.2 7.5 1.3 8.9 0.3 3.1 3 0 0 3 3 3 0 Cysteine-rich KTR zf-C4_Topoisom PF01396.19 EAY00761.1 - 5.5 6.9 10.5 9.1 6.2 0.1 3.4 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Ank_4 PF13637.6 EAY00762.1 - 3.2e-08 34.0 0.2 2.5e-06 27.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00762.1 - 6e-08 33.2 0.3 1.2e-06 29.0 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00762.1 - 2.3e-06 27.8 0.2 0.02 15.3 0.0 2.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAY00762.1 - 5.4e-06 26.4 0.2 0.029 14.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAY00762.1 - 0.00029 21.0 0.2 0.019 15.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_C1 PF00112.23 EAY00763.1 - 2.4e-72 243.5 9.7 3e-72 243.3 9.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAY00763.1 - 5.3e-12 46.0 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAY00763.1 - 0.0041 15.9 4.6 0.39 9.4 0.9 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Caudo_TAP PF02413.17 EAY00764.1 - 0.004 17.3 0.8 0.0092 16.1 0.8 1.6 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK DUF2098 PF09871.9 EAY00764.1 - 2.9 8.3 6.6 8 6.9 6.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Ank_2 PF12796.7 EAY00765.1 - 9.8e-10 38.9 0.0 1.5e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00765.1 - 2.7e-08 33.9 0.0 3.8e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY00765.1 - 2.9e-08 33.8 0.0 3.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00765.1 - 1.7e-06 28.5 0.0 8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00765.1 - 0.00027 21.2 0.0 0.0024 18.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EAY00766.1 - 8.9e-127 414.0 7.0 4.1e-20 72.2 0.0 9.9 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00766.1 - 1.3e-102 332.2 1.6 1.1e-05 25.6 0.0 17.5 17 0 0 17 17 17 17 Ankyrin repeat Ank_4 PF13637.6 EAY00766.1 - 1e-95 313.0 4.0 5.8e-10 39.5 0.0 13.2 8 4 5 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00766.1 - 2.2e-91 298.7 5.4 1.1e-07 32.0 0.0 16.9 1 1 16 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00766.1 - 4.2e-78 247.9 0.1 0.0019 18.6 0.0 17.4 17 0 0 17 17 17 17 Ankyrin repeat L_protein_N PF15518.6 EAY00766.1 - 2.5e-15 56.1 0.0 17 5.4 0.0 12.9 3 2 12 15 15 15 0 L protein N-terminus DUF1897 PF09005.10 EAY00766.1 - 2.7e-08 33.2 0.7 3e+02 1.0 0.0 11.8 16 0 0 16 16 16 0 Domain of unknown function (DUF1897) DUF3552 PF12072.8 EAY00766.1 - 0.036 13.5 0.2 0.067 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF5427 PF10310.9 EAY00766.1 - 0.038 12.9 0.3 0.062 12.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ABC_tran_Xtn PF12848.7 EAY00766.1 - 0.042 13.9 1.9 0.074 13.1 1.9 1.4 1 0 0 1 1 1 0 ABC transporter YabA PF06156.13 EAY00766.1 - 0.057 14.1 1.5 0.14 12.9 1.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Lip_prot_lig_C PF10437.9 EAY00766.1 - 0.094 12.7 1.7 0.12 12.4 0.2 1.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus PriCT_2 PF08707.11 EAY00766.1 - 0.15 12.4 0.1 40 4.7 0.0 2.8 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Csm1_N PF18504.1 EAY00766.1 - 0.64 10.4 4.7 1.4 9.3 4.7 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain HNF-1B_C PF04812.13 EAY00766.1 - 0.88 9.4 11.0 4.7 7.0 1.1 5.0 2 2 3 5 5 5 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus FlxA PF14282.6 EAY00766.1 - 1 9.4 7.7 2.2 8.3 7.7 1.6 1 0 0 1 1 1 0 FlxA-like protein SAM_2 PF07647.17 EAY00767.1 - 5.8e-07 29.5 0.0 9.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAY00767.1 - 7.2e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 EAY00767.1 - 0.00061 19.6 0.6 0.001 18.9 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type YacG PF03884.14 EAY00767.1 - 0.037 13.8 0.9 0.068 12.9 0.9 1.4 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Rad50_zn_hook PF04423.14 EAY00767.1 - 0.089 12.6 0.2 0.089 12.6 0.2 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Myb_DNA-binding PF00249.31 EAY00769.1 - 6.6e-36 122.3 6.2 4.3e-18 65.2 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00769.1 - 2e-26 92.0 1.1 3.6e-12 46.4 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY00769.1 - 1.5e-05 25.0 0.0 0.26 11.3 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY00769.1 - 0.0049 16.7 0.0 0.78 9.7 0.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Sigma70_r4_2 PF08281.12 EAY00769.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Rap1_C PF11626.8 EAY00769.1 - 0.019 15.0 0.3 1 9.5 0.0 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAY00769.1 - 0.026 14.7 0.1 2.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EAY00769.1 - 0.16 12.2 1.3 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 EAY00769.1 - 0.16 12.0 0.0 0.67 10.0 0.0 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EAY00769.1 - 1.3 9.4 3.8 23 5.5 0.3 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain IKKbetaNEMObind PF12179.8 EAY00771.1 - 0.097 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Intein_splicing PF14890.6 EAY00772.1 - 0.043 13.8 2.3 0.054 13.4 2.3 1.2 1 0 0 1 1 1 0 Intein splicing domain DUF4114 PF13448.6 EAY00773.1 - 0.15 12.9 0.2 0.15 12.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) Glyco_hydro_67N PF03648.14 EAY00773.1 - 0.28 11.5 0.9 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus DUF3839 PF12943.7 EAY00774.1 - 4.4e-157 520.8 12.1 5.5e-157 520.4 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY00774.1 - 0.16 12.4 5.2 0.49 10.9 0.5 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY00774.1 - 0.68 10.3 5.7 12 6.2 0.0 4.1 4 1 0 4 4 4 0 Tup N-terminal RPN2_C PF18004.1 EAY00776.1 - 6.1e-15 55.5 3.0 1.6e-08 34.6 2.6 2.4 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EAY00776.1 - 6.5e-15 55.3 3.1 3.6e-06 27.3 0.0 5.9 4 4 2 6 6 6 2 HEAT repeats PC_rep PF01851.22 EAY00776.1 - 3.6e-14 52.4 27.3 1.7e-07 31.3 0.0 8.5 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT PF02985.22 EAY00776.1 - 0.0022 18.1 2.4 3.9 8.0 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EAY00776.1 - 0.0045 17.0 0.1 0.5 10.4 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAY00776.1 - 0.35 11.4 2.0 69 4.1 0.2 4.1 3 1 0 3 3 3 0 HEAT-like repeat TPR_14 PF13428.6 EAY00776.1 - 0.52 11.3 2.2 30 5.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PSP PF04046.16 EAY00777.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00778.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat Ank_2 PF12796.7 EAY00780.1 - 1.1e-112 368.8 68.3 1.9e-16 60.4 2.4 6.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00780.1 - 1.1e-105 344.8 34.5 1.6e-14 54.1 0.2 10.8 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EAY00780.1 - 5.2e-90 292.3 29.6 8.1e-08 32.4 0.1 10.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 EAY00780.1 - 4.2e-84 275.5 56.0 2e-11 43.9 0.7 7.4 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00780.1 - 4.3e-83 263.2 14.0 2.3e-06 27.5 0.0 10.6 11 0 0 11 11 11 10 Ankyrin repeat DUF3718 PF12514.8 EAY00780.1 - 3.5e-15 55.9 40.7 0.77 10.0 0.1 10.0 7 2 3 10 10 10 8 Protein of unknown function (DUF3718) PAZ_siRNAbind PF12212.8 EAY00780.1 - 2.7e-07 30.5 6.4 97 2.8 0.0 9.7 1 1 10 11 11 11 0 PAZ domain CCDC84 PF14968.6 EAY00780.1 - 0.00036 20.3 33.3 11 5.5 0.1 9.1 1 1 9 10 10 10 2 Coiled coil protein 84 Stap_Strp_toxin PF01123.20 EAY00780.1 - 0.8 10.6 16.0 80 4.2 0.3 5.6 1 1 7 8 8 8 0 Staphylococcal/Streptococcal toxin, OB-fold domain Env-gp36 PF09590.10 EAY00780.1 - 2.1 6.7 6.5 29 2.9 0.3 3.2 1 1 4 5 5 5 0 Lentivirus surface glycoprotein Gas_vesicle_C PF01304.17 EAY00780.1 - 9.7 6.3 15.8 6.1e+02 0.5 0.0 8.0 9 0 0 9 9 9 0 Gas vesicles protein GVPc repeated domain DUF3447 PF11929.8 EAY00781.1 - 2.1e-35 120.5 5.4 2.1e-35 120.5 5.4 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00781.1 - 3.2e-06 27.7 0.1 0.00013 22.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ATP13 PF12921.7 EAY00781.1 - 0.0037 17.1 1.8 0.0037 17.1 1.8 2.4 2 1 1 3 3 3 1 Mitochondrial ATPase expression Ank_4 PF13637.6 EAY00781.1 - 0.048 14.3 0.3 31 5.3 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Arc_PepC PF06819.11 EAY00781.1 - 0.11 12.6 0.5 3.4 7.8 0.2 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain DUF4577 PF15145.6 EAY00782.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) PHD PF00628.29 EAY00783.1 - 2.5e-06 27.3 9.6 3.7e-06 26.7 9.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAY00783.1 - 0.0058 16.2 5.0 0.009 15.6 5.0 1.3 1 0 0 1 1 1 1 PHD-finger VASt PF16016.5 EAY00783.1 - 0.016 15.6 0.2 0.022 15.2 0.2 1.2 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain zf-HC5HC2H PF13771.6 EAY00783.1 - 0.04 14.2 3.7 0.085 13.1 3.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-CW PF07496.15 EAY00783.1 - 0.16 12.0 2.8 0.34 11.0 2.8 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Spc7 PF08317.11 EAY00784.1 - 0.028 13.3 79.3 0.088 11.7 38.0 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAY00784.1 - 6.4 6.0 56.7 0.054 12.8 15.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L21e PF01157.18 EAY00785.1 - 2.3e-38 130.1 0.3 3.3e-38 129.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_L21e PF01157.18 EAY00786.1 - 1.4e-38 130.8 0.3 1.7e-38 130.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e Gly_rich PF12810.7 EAY00788.1 - 4.2e-58 197.1 33.9 5.2e-58 196.8 33.9 1.1 1 0 0 1 1 1 1 Glycine rich protein F5_F8_type_C PF00754.25 EAY00791.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.6 2 0 0 2 2 2 1 F5/8 type C domain COP23 PF14218.6 EAY00791.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Steroid_dh PF02544.16 EAY00792.1 - 2.2e-19 69.9 3.5 2.2e-19 69.9 3.5 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF997 PF06196.12 EAY00792.1 - 0.29 11.2 5.3 0.47 10.5 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Pyrophosphatase PF00719.19 EAY00793.1 - 7.2e-47 159.2 0.0 9.8e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase HSP70 PF00012.20 EAY00795.1 - 1.6e-232 773.0 9.6 2e-232 772.7 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAY00795.1 - 7e-17 61.2 1.8 1.2e-14 53.9 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 EAY00795.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EAY00795.1 - 0.032 14.6 2.9 5.3 7.5 0.3 3.3 2 2 0 2 2 2 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EAY00795.1 - 0.061 12.6 0.4 0.45 9.7 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SabA_adhesion PF18304.1 EAY00795.1 - 0.16 11.2 1.1 0.29 10.3 1.1 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain GBP_C PF02841.14 EAY00795.1 - 0.3 10.4 14.7 0.68 9.3 14.7 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain hDGE_amylase PF14701.6 EAY00795.1 - 1.9 7.5 8.8 1.4 8.0 5.4 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Proteasome PF00227.26 EAY00796.1 - 9.2e-41 139.4 0.1 1.1e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1493 PF07377.12 EAY00797.1 - 0.034 14.6 0.6 0.076 13.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PSP PF04046.16 EAY00798.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP ANAPC4_WD40 PF12894.7 EAY00799.1 - 8.7e-20 70.8 0.0 8.4e-05 22.8 0.0 5.7 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAY00799.1 - 3.4e-15 56.2 4.6 0.00066 20.4 0.1 6.9 7 1 1 8 8 8 4 WD domain, G-beta repeat LisH PF08513.11 EAY00799.1 - 3.7e-05 23.5 0.2 8.1e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 EAY00799.1 - 0.0014 18.0 0.0 0.11 11.8 0.0 2.4 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 EAY00799.1 - 0.0015 18.4 0.3 1.9 8.4 0.0 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 EAY00799.1 - 0.0051 16.4 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EAY00799.1 - 0.03 14.2 0.2 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Helicase_C PF00271.31 EAY00801.1 - 6.4e-16 58.7 0.1 6.5e-15 55.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAY00801.1 - 9.2e-13 48.3 0.1 2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EAY00801.1 - 1.3e-11 44.8 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAY00801.1 - 2.1e-07 31.2 0.0 7.2e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SRP54 PF00448.22 EAY00801.1 - 0.0003 20.5 0.2 0.0028 17.3 0.1 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EAY00801.1 - 0.00039 20.8 0.0 0.0073 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAY00801.1 - 0.00049 19.9 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAY00801.1 - 0.0028 17.7 1.0 0.038 14.0 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAY00801.1 - 0.0047 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAY00801.1 - 0.0069 15.7 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EAY00801.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Herpes_ori_bp PF02399.15 EAY00801.1 - 0.01 14.0 0.0 0.016 13.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_23 PF13476.6 EAY00801.1 - 0.021 15.4 0.5 0.42 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAY00801.1 - 0.027 13.9 0.2 0.078 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 EAY00801.1 - 0.029 13.4 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EAY00801.1 - 0.067 12.8 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EAY00801.1 - 0.076 13.0 0.3 1.8 8.6 0.1 3.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAY00801.1 - 0.44 10.4 2.6 0.69 9.8 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PQ-loop PF04193.14 EAY00802.1 - 3.3e-28 97.2 17.2 7.6e-17 60.8 3.0 2.8 3 0 0 3 3 3 2 PQ loop repeat DEAD PF00270.29 EAY00803.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAY00803.1 - 0.0019 18.0 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAY00803.1 - 0.0038 16.3 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EAY00803.1 - 0.0039 16.7 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 EAY00803.1 - 0.014 15.7 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAY00803.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EAY00803.1 - 0.033 14.7 0.2 0.055 14.0 0.2 1.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAY00803.1 - 0.036 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 EAY00803.1 - 0.037 13.7 0.1 0.076 12.7 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 EAY00803.1 - 0.052 13.8 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 EAY00803.1 - 0.057 11.5 0.0 0.058 11.4 0.0 1.0 1 0 0 1 1 1 0 Origin of replication binding protein AAA_11 PF13086.6 EAY00803.1 - 0.066 13.0 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAY00803.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 EAY00803.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 EAY00803.1 - 0.12 11.6 0.1 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 EAY00803.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EAY00803.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1664 PF07889.12 EAY00804.1 - 0.0087 16.1 2.2 0.0087 16.1 2.2 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) DUF3015 PF11220.8 EAY00804.1 - 0.043 13.7 0.3 0.086 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF948 PF06103.11 EAY00804.1 - 0.25 11.6 8.7 0.38 11.0 1.7 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4208 PF13907.6 EAY00804.1 - 0.43 11.0 4.1 0.48 10.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) AvrM-A PF18241.1 EAY00804.1 - 1.6 9.2 10.3 0.25 11.8 5.1 2.0 1 1 1 2 2 2 0 Flax-rust effector AvrM-A DUF3839 PF12943.7 EAY00805.1 - 7.8e-154 510.1 13.5 1e-153 509.8 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Amidase02_C PF12123.8 EAY00806.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAY00807.1 - 8.1e-73 243.9 3.8 1.1e-72 243.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Gly_rich PF12810.7 EAY00808.1 - 9.5e-41 140.3 42.8 1.1e-40 140.1 42.8 1.0 1 0 0 1 1 1 1 Glycine rich protein NAD_Gly3P_dh_C PF07479.14 EAY00809.1 - 8.7e-35 120.1 1.3 1.5e-34 119.3 0.3 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EAY00809.1 - 3.9e-32 111.4 0.0 8.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EppA_BapA PF07268.11 EAY00810.1 - 0.0022 17.9 1.0 0.46 10.4 0.1 2.3 1 1 1 2 2 2 2 Exported protein precursor (EppA/BapA) MG2 PF01835.19 EAY00811.1 - 0.00056 20.3 0.0 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 MG2 domain BetaGal_dom4_5 PF13364.6 EAY00811.1 - 0.0011 19.5 0.0 0.048 14.2 0.0 2.5 1 1 1 2 2 2 1 Beta-galactosidase jelly roll domain DUF4251 PF14059.6 EAY00811.1 - 0.0017 18.3 1.4 0.014 15.4 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4251) DUF2808 PF10989.8 EAY00811.1 - 0.01 15.8 2.7 0.35 10.9 0.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2808) DUF4767 PF15983.5 EAY00811.1 - 0.016 15.5 0.3 0.027 14.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) DUF1616 PF07760.11 EAY00811.1 - 0.017 14.6 1.0 0.2 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF4577 PF15145.6 EAY00811.1 - 0.027 14.5 0.2 0.048 13.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2273 PF10031.9 EAY00811.1 - 0.033 14.2 2.8 0.074 13.1 2.8 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) ETRAMP PF09716.10 EAY00811.1 - 0.048 13.7 0.1 0.048 13.7 0.1 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Laminin_G_3 PF13385.6 EAY00811.1 - 0.14 12.3 0.3 0.36 11.0 0.3 1.8 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Cadherin-like PF12733.7 EAY00811.1 - 0.16 12.5 6.8 0.16 12.5 0.4 3.3 3 1 1 4 4 4 0 Cadherin-like beta sandwich domain DUF4625 PF15418.6 EAY00812.1 - 0.00041 20.6 0.3 0.034 14.4 0.2 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) MG2 PF01835.19 EAY00812.1 - 0.002 18.5 0.0 0.045 14.2 0.0 2.8 2 1 0 2 2 2 1 MG2 domain Orf78 PF06024.12 EAY00812.1 - 0.023 15.0 0.1 0.049 13.9 0.1 1.7 1 1 0 1 1 1 0 Orf78 (ac78) Cohesin PF00963.18 EAY00812.1 - 0.11 12.8 8.9 0.65 10.2 0.3 2.9 2 1 0 3 3 3 0 Cohesin domain I-set PF07679.16 EAY00812.1 - 0.12 12.5 2.0 0.41 10.7 0.1 2.8 3 0 0 3 3 3 0 Immunoglobulin I-set domain Fib_alpha PF08702.10 EAY00813.1 - 0.0085 16.3 37.9 0.2 11.9 15.1 2.7 1 1 0 2 2 2 2 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EAY00813.1 - 0.034 14.2 27.8 0.37 10.8 5.7 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.9 EAY00813.1 - 0.036 14.0 0.2 0.036 14.0 0.2 4.7 2 2 2 4 4 4 0 Short coiled-coil protein Laminin_II PF06009.12 EAY00813.1 - 0.038 14.0 30.8 0.52 10.3 10.9 2.8 1 1 0 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 EAY00813.1 - 0.054 14.0 28.6 3.8 8.1 9.0 3.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 EAY00813.1 - 0.068 13.9 30.7 0.78 10.5 2.3 4.3 1 1 3 4 4 4 0 Occludin homology domain LPP PF04728.13 EAY00813.1 - 0.088 13.2 30.2 1.2 9.6 0.1 6.0 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Syntaxin_2 PF14523.6 EAY00813.1 - 0.11 12.9 42.1 0.81 10.1 7.9 3.8 2 1 2 4 4 4 0 Syntaxin-like protein DUF948 PF06103.11 EAY00813.1 - 0.13 12.5 23.2 13 6.1 3.7 4.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EAY00813.1 - 0.18 11.1 42.5 0.74 9.1 15.7 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Lant_dehydr_C PF14028.6 EAY00813.1 - 0.19 11.2 8.0 1.8 8.0 2.1 2.4 1 1 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term AAA_13 PF13166.6 EAY00813.1 - 0.23 10.1 46.0 0.083 11.5 13.6 2.4 1 1 1 2 2 2 0 AAA domain FPP PF05911.11 EAY00813.1 - 0.25 9.5 39.9 0.42 8.7 39.9 1.3 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 EAY00813.1 - 0.28 11.3 41.1 0.29 11.2 13.0 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EAY00813.1 - 0.67 10.0 51.0 0.24 11.5 14.1 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 EAY00813.1 - 0.71 9.4 35.9 2 7.9 22.4 4.1 1 1 1 2 2 2 0 PspA/IM30 family TSC22 PF01166.18 EAY00813.1 - 0.9 9.9 0.1 0.9 9.9 0.1 4.8 3 2 2 5 5 5 0 TSC-22/dip/bun family FapA PF03961.13 EAY00813.1 - 1 7.9 40.3 1.2 7.7 19.5 2.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A ApoO PF09769.9 EAY00813.1 - 1.9 8.4 13.8 17 5.4 1.8 3.9 2 2 2 4 4 4 0 Apolipoprotein O DUF4854 PF16146.5 EAY00813.1 - 2.2 8.6 20.1 0.45 10.9 8.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4854) DUF1993 PF09351.10 EAY00813.1 - 3 8.0 15.7 0.14 12.3 3.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1993) Golgin_A5 PF09787.9 EAY00813.1 - 3.2 7.1 43.3 1.7 8.0 23.0 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF2353 PF09789.9 EAY00813.1 - 4 6.7 41.2 0.061 12.7 17.5 3.0 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) CorA PF01544.18 EAY00813.1 - 4.4 6.5 25.0 0.73 9.1 5.2 3.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein HAUS5 PF14817.6 EAY00813.1 - 7.6 5.2 34.8 0.098 11.4 3.0 3.7 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.11 EAY00813.1 - 8 6.9 20.9 1.8 9.0 0.4 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF3138 PF11336.8 EAY00813.1 - 8.9 4.8 14.4 2.5 6.6 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Myb_DNA-binding PF00249.31 EAY00814.1 - 4.1e-26 90.9 0.0 1.3e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00814.1 - 2.7e-22 78.8 0.1 7.2e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY00814.1 - 3.6e-08 33.2 1.6 3e-05 23.8 0.7 2.7 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAY00814.1 - 1.7e-05 24.8 0.9 0.07 13.2 0.0 3.3 1 1 1 2 2 2 2 SLIDE DUF4065 PF13274.6 EAY00814.1 - 0.048 14.6 0.8 0.32 11.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) SnAPC_2_like PF11035.8 EAY00814.1 - 0.098 12.8 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Pyr_redox PF00070.27 EAY00814.1 - 0.14 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EAY00815.1 - 2.8e-23 82.6 0.0 5.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00815.1 - 5.2e-09 35.8 0.0 8.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00815.1 - 1.9e-06 27.5 0.0 6.3e-06 25.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EAY00815.1 - 0.0073 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAY00815.1 - 0.042 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_CoA_synt_N PF01154.17 EAY00816.1 - 2.8e-65 219.4 0.0 4.6e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EAY00816.1 - 1.4e-53 182.3 0.5 3.6e-53 181.0 0.5 1.6 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 EAY00816.1 - 0.027 14.6 0.2 0.18 12.0 0.1 2.1 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlphaC_C PF17480.2 EAY00817.1 - 0.028 14.4 1.0 0.038 14.0 1.0 1.1 1 0 0 1 1 1 0 AlphaC C-terminal DUF2207 PF09972.9 EAY00817.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 EAY00818.1 - 2e-90 297.5 57.1 7.4e-16 58.5 3.4 7.5 2 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00818.1 - 3.4e-77 253.9 30.1 4.1e-12 46.4 0.3 11.9 4 1 8 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EAY00818.1 - 1.6e-67 221.2 31.0 7.9e-07 29.3 0.0 12.0 11 1 1 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAY00818.1 - 5.1e-57 189.2 26.6 5.9e-11 42.4 0.2 8.9 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00818.1 - 1.1e-48 157.5 25.8 3.4e-06 27.0 0.0 12.5 13 0 0 13 13 13 10 Ankyrin repeat DUF3447 PF11929.8 EAY00818.1 - 3.1e-36 123.2 9.3 3.1e-36 123.2 9.3 7.6 5 2 3 8 8 8 2 Domain of unknown function (DUF3447) PEGA PF08308.11 EAY00818.1 - 0.0075 16.1 0.0 0.36 10.8 0.0 3.7 6 0 0 6 6 6 1 PEGA domain ATPase PF06745.13 EAY00818.1 - 0.02 14.2 0.3 0.048 13.0 0.3 1.5 1 0 0 1 1 1 0 KaiC GATase_7 PF13537.6 EAY00818.1 - 0.025 14.5 0.1 39 4.2 0.0 4.7 5 2 1 6 6 6 0 Glutamine amidotransferase domain Phage_T7_Capsid PF05396.11 EAY00818.1 - 0.23 11.8 3.7 15 6.0 0.2 3.0 2 1 0 2 2 2 0 Phage T7 capsid assembly protein SLBP_RNA_bind PF15247.6 EAY00819.1 - 0.024 14.8 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Gly_rich PF12810.7 EAY00820.1 - 7.3e-46 157.0 42.5 8.6e-46 156.8 42.5 1.0 1 0 0 1 1 1 1 Glycine rich protein EGF_3 PF12947.7 EAY00822.1 - 0.23 11.7 5.5 0.5 10.6 5.5 1.6 1 0 0 1 1 1 0 EGF domain EGF_Tenascin PF18720.1 EAY00822.1 - 0.33 11.0 3.3 0.73 10.0 3.3 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EAY00822.1 - 4.5 7.7 9.9 9.2 6.7 9.9 1.5 1 0 0 1 1 1 0 EGF-like domain Beach PF02138.18 EAY00823.1 - 3.5e-75 252.9 1.7 7.7e-75 251.8 1.7 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Rhodanese_C PF12368.8 EAY00823.1 - 0.0024 18.2 7.6 0.0095 16.3 7.6 2.0 1 0 0 1 1 1 1 Rhodanase C-terminal DZR PF12773.7 EAY00823.1 - 0.2 11.7 7.5 0.84 9.7 7.5 2.1 1 0 0 1 1 1 0 Double zinc ribbon Ank_2 PF12796.7 EAY00826.1 - 4.6e-11 43.2 0.0 4.8e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY00826.1 - 3.7e-07 29.9 0.0 0.00019 21.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY00826.1 - 7.2e-07 29.4 0.0 4.6e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00826.1 - 1.5e-06 28.7 0.0 3.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY00826.1 - 1.6e-06 28.3 0.0 0.00078 19.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat PSP PF04046.16 EAY00827.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00828.1 - 0.076 13.6 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00829.1 - 0.067 13.7 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00830.1 - 1e-36 124.8 30.0 6.6e-33 112.6 13.8 6.2 4 2 2 6 6 6 3 Phage tail repeat like DUF4116 PF13475.6 EAY00830.1 - 0.032 13.9 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3839 PF12943.7 EAY00833.1 - 1.3e-156 519.2 12.7 1.7e-156 518.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY00833.1 - 0.02 15.3 2.0 0.081 13.4 0.4 2.1 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAY00833.1 - 0.37 11.3 6.2 1.9 9.0 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY00833.1 - 0.69 10.3 6.2 11 6.4 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal DUF2408 PF10303.9 EAY00833.1 - 3 8.4 7.2 0.45 11.1 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KilA-N PF04383.13 EAY00834.1 - 1e-44 150.9 0.6 2.2e-44 149.9 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain Parathyroid PF01279.17 EAY00834.1 - 0.005 17.4 0.2 0.018 15.7 0.0 2.0 3 0 0 3 3 3 1 Parathyroid hormone family DUF4106 PF13388.6 EAY00835.1 - 4.4e-227 754.2 19.1 4.4e-227 754.2 19.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAY00835.1 - 0.061 13.6 2.4 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Kidney androgen-regulated ArsC PF03960.15 EAY00835.1 - 0.59 10.2 2.4 1.4 9.0 0.1 2.8 3 0 0 3 3 3 0 ArsC family Pkinase PF00069.25 EAY00839.1 - 4.2e-08 32.9 0.0 1.3e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF3447 PF11929.8 EAY00839.1 - 0.13 12.2 0.9 0.43 10.6 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Ribosomal_L36e PF01158.18 EAY00840.1 - 8.1e-21 74.1 2.4 9.7e-21 73.8 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EAY00840.1 - 0.05 13.4 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DHC_N2 PF08393.13 EAY00841.1 - 9.8e-76 255.4 10.8 9.8e-76 255.4 10.8 5.5 6 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EAY00841.1 - 3e-21 75.8 6.2 3.2e-21 75.6 1.7 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EAY00841.1 - 3.2e-06 26.8 1.5 0.0055 16.2 0.1 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 EAY00841.1 - 3.8e-06 27.0 0.0 5.3e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EAY00841.1 - 6.5e-05 22.8 0.0 0.00057 19.7 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EAY00841.1 - 0.00014 22.2 0.4 0.022 15.0 0.0 4.0 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.6 EAY00841.1 - 0.033 14.7 0.3 1.6 9.3 0.0 3.8 4 0 0 4 4 2 0 AAA domain DRTGG PF07085.12 EAY00841.1 - 0.05 13.4 0.1 2 8.2 0.0 2.9 2 0 0 2 2 2 0 DRTGG domain RNA_helicase PF00910.22 EAY00841.1 - 0.091 13.2 0.0 19 5.7 0.0 3.3 2 0 0 2 2 2 0 RNA helicase Gon7 PF08738.10 EAY00841.1 - 0.098 12.8 1.9 0.24 11.5 1.9 1.6 1 0 0 1 1 1 0 Gon7 family ABC_tran PF00005.27 EAY00841.1 - 0.11 13.0 0.0 26 5.3 0.0 3.5 2 0 0 2 2 2 0 ABC transporter Sec8_exocyst PF04048.14 EAY00841.1 - 0.18 11.7 14.3 0.27 11.1 0.9 5.0 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain Fez1 PF06818.15 EAY00841.1 - 1.8 9.0 10.8 9.8 6.6 1.2 3.3 2 0 0 2 2 2 0 Fez1 DUF4108 PF13390.6 EAY00842.1 - 9.2e-70 233.1 12.4 1.1e-69 232.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAY00843.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAY00843.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY00843.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Y_phosphatase2 PF03162.13 EAY00845.1 - 0.04 13.5 0.2 0.062 12.9 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAY00845.1 - 0.042 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 tRNA_synt_1c_R1 PF04558.15 EAY00845.1 - 0.055 13.5 0.3 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 TPR_MLP1_2 PF07926.12 EAY00846.1 - 0.012 15.7 0.8 0.015 15.4 0.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 EAY00846.1 - 0.44 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Ank_2 PF12796.7 EAY00847.1 - 5.6e-24 84.5 13.2 2.4e-15 56.9 4.9 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY00847.1 - 4.3e-18 65.0 7.2 4.3e-18 65.0 7.2 3.5 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY00847.1 - 4.4e-18 65.4 1.1 7.7e-13 48.7 0.2 4.6 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY00847.1 - 2.7e-17 62.4 4.0 9.1e-08 32.2 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAY00847.1 - 3.3e-16 57.7 1.3 6.1e-05 23.1 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EAY00847.1 - 2.7e-14 53.0 0.7 9.3e-08 32.2 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00848.1 - 1.4e-44 149.5 17.6 8.8e-12 45.0 0.6 6.4 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY00848.1 - 1.3e-42 144.2 8.6 1e-14 54.9 0.9 5.4 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00848.1 - 1.7e-33 114.6 18.5 9.9e-10 38.8 0.1 9.0 3 3 6 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00848.1 - 4.3e-31 106.7 6.4 4.3e-31 106.7 6.4 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAY00848.1 - 4.6e-29 99.6 5.7 2e-06 28.0 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 EAY00848.1 - 1.1e-28 96.1 15.8 3.6e-06 26.9 0.1 9.8 11 0 0 11 11 11 5 Ankyrin repeat APG6_N PF17675.1 EAY00850.1 - 0.0031 18.1 9.9 0.0031 18.1 9.9 4.2 2 1 2 4 4 4 1 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EAY00850.1 - 0.014 15.4 38.7 0.024 14.6 5.8 4.1 1 1 2 3 3 3 0 Axonemal dynein light chain TRPM_tetra PF16519.5 EAY00850.1 - 0.16 12.1 4.3 4.1 7.6 0.1 3.6 3 0 0 3 3 3 0 Tetramerisation domain of TRPM Phage_holin_6_1 PF09682.10 EAY00850.1 - 1.1 9.7 12.1 0.66 10.4 3.7 3.5 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) PEP-utilisers_N PF05524.13 EAY00850.1 - 1.3 9.2 7.2 0.25 11.5 1.2 2.9 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal DUF948 PF06103.11 EAY00850.1 - 2.6 8.3 14.8 1.1 9.6 1.3 5.0 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 EAY00850.1 - 4.8 7.5 9.2 98 3.3 0.7 4.8 5 0 0 5 5 5 0 Proteins of 100 residues with WXG SesA PF17107.5 EAY00850.1 - 6.1 7.1 11.6 0.32 11.2 4.0 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases IBD PF10416.9 EAY00851.1 - 2e-17 63.4 0.0 2.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DHR10 PF18595.1 EAY00852.1 - 2.8 8.0 43.6 3.6 7.7 13.4 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF3447 PF11929.8 EAY00853.1 - 1e-17 63.8 6.3 1e-17 63.8 6.3 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00853.1 - 5.3e-16 59.0 7.3 4e-13 49.8 1.8 3.8 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY00853.1 - 1.9e-15 56.7 5.9 3.8e-07 30.2 0.2 5.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00853.1 - 2.4e-14 53.5 8.4 1.1e-06 29.0 0.1 5.6 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00853.1 - 6.9e-12 44.5 5.8 0.0006 20.1 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAY00853.1 - 1.7e-07 31.3 1.7 0.28 11.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ribosomal_S19e PF01090.19 EAY00854.1 - 4.9e-46 155.8 0.3 5.5e-46 155.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_45 PF14947.6 EAY00854.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_12 PF08461.10 EAY00854.1 - 0.026 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Rrf2 PF02082.20 EAY00854.1 - 0.032 14.6 0.1 0.094 13.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator RuvB_C PF05491.13 EAY00854.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 RuvB C-terminal winged helix domain CdiA_C_tRNase PF18664.1 EAY00854.1 - 0.1 12.8 0.1 0.31 11.2 0.0 1.8 2 1 0 2 2 2 0 CdiA C-terminal tRNase domain Tubulin PF00091.25 EAY00856.1 - 8.9e-51 172.9 0.1 1.3e-50 172.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 EAY00856.1 - 0.019 14.2 0.1 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Tubulin like MHC_II_beta PF00969.19 EAY00857.1 - 0.23 11.6 3.1 2.8 8.1 0.3 3.2 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain Ank_2 PF12796.7 EAY00858.1 - 5.9e-35 119.7 3.4 1.2e-16 61.0 0.2 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00858.1 - 3.2e-32 110.5 2.4 1.7e-15 57.1 0.1 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00858.1 - 3.6e-25 87.7 0.6 1e-10 41.6 0.1 2.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY00858.1 - 1.2e-22 79.6 10.5 8.4e-22 76.9 6.1 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY00858.1 - 2.2e-20 70.6 0.6 1.7e-05 24.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAY00858.1 - 4.2e-19 68.1 0.0 4.5e-07 30.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat HeH PF12949.7 EAY00858.1 - 0.12 12.1 1.1 4 7.2 0.0 2.9 3 0 0 3 3 3 0 HeH/LEM domain FliJ PF02050.16 EAY00859.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAY00860.1 - 4e-72 241.7 3.8 6e-72 241.1 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF5007 PF16398.5 EAY00862.1 - 0.021 14.5 0.1 0.026 14.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) DUF3839 PF12943.7 EAY00864.1 - 1.2e-53 182.1 3.0 1.4e-53 181.9 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF3839 PF12943.7 EAY00865.1 - 9.9e-157 519.6 12.7 1.2e-156 519.3 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY00865.1 - 0.072 13.5 1.4 0.28 11.6 0.2 2.0 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAY00865.1 - 0.16 11.8 1.7 0.39 10.5 0.4 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY00865.1 - 2.1 8.9 5.5 7.6 7.1 0.2 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAY00866.1 - 2.9e-22 78.5 20.9 2.8e-16 59.3 2.5 5.3 5 1 0 5 5 5 2 Phage tail repeat like DUF4795 PF16043.5 EAY00866.1 - 0.015 14.9 1.5 0.015 14.9 1.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4116 PF13475.6 EAY00866.1 - 0.084 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAY00866.1 - 0.13 12.2 3.3 2.1 8.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) TMP PF05017.14 EAY00868.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY00869.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAY00870.1 - 2.7e-34 117.0 4.7 2.7e-34 117.0 4.7 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY00870.1 - 8.7e-24 83.9 6.0 2.7e-12 47.1 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00870.1 - 3e-20 71.7 6.1 1.6e-07 31.4 1.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAY00870.1 - 6.6e-20 70.9 7.7 1.2e-09 38.2 0.1 4.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00870.1 - 3.3e-18 65.8 11.9 1.4e-08 35.1 0.1 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00870.1 - 4e-13 48.2 7.5 0.00018 21.6 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat DUF3810 PF12725.7 EAY00870.1 - 0.72 9.1 5.8 0.26 10.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Vps16_N PF04841.13 EAY00872.1 - 4.5e-12 45.4 0.0 7.3e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAY00872.1 - 0.0077 15.3 0.1 0.017 14.1 0.1 1.6 1 0 0 1 1 1 1 Vps16, C-terminal region COG5 PF10392.9 EAY00872.1 - 0.71 10.1 2.9 0.53 10.5 0.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Oxidored_FMN PF00724.20 EAY00873.1 - 4.9e-61 206.9 0.0 6e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 EAY00873.1 - 1.2e-05 24.9 0.2 2.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 EAY00873.1 - 0.0021 17.2 0.0 0.0053 15.8 0.0 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Fer4_18 PF13746.6 EAY00873.1 - 0.012 15.8 0.2 0.025 14.7 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain IMPDH PF00478.25 EAY00873.1 - 0.064 12.2 0.2 0.19 10.7 0.1 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain AP_endonuc_2 PF01261.24 EAY00873.1 - 0.13 11.7 0.0 0.48 9.8 0.0 1.7 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Fer4 PF00037.27 EAY00873.1 - 0.27 11.1 2.3 0.76 9.7 2.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Myb_DNA-binding PF00249.31 EAY00874.1 - 1.4e-27 95.6 4.7 5.9e-16 58.4 1.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY00874.1 - 1.6e-20 73.1 8.5 7.6e-16 58.1 2.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAY00874.1 - 0.00027 21.1 0.9 0.014 15.5 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Lycopene_cycl PF05834.12 EAY00874.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein SLIDE PF09111.10 EAY00874.1 - 0.0053 16.8 4.3 0.041 13.9 0.2 3.1 1 1 2 3 3 3 1 SLIDE XH PF03469.14 EAY00874.1 - 0.0092 15.9 1.3 0.01 15.8 0.2 1.6 2 0 0 2 2 2 1 XH domain Myb_DNA-bind_4 PF13837.6 EAY00874.1 - 0.018 15.4 11.3 0.26 11.7 0.9 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY00874.1 - 0.061 13.2 4.0 0.39 10.6 0.2 2.4 1 1 1 2 2 2 0 Myb DNA-binding like FG-GAP_2 PF14312.6 EAY00875.1 - 2.9e-08 33.8 3.1 9.3e-06 25.8 0.2 4.1 4 0 0 4 4 4 2 FG-GAP repeat L51_S25_CI-B8 PF05047.16 EAY00876.1 - 0.1 12.5 0.1 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FleQ PF06490.11 EAY00876.1 - 0.13 12.6 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Tropomyosin_1 PF12718.7 EAY00877.1 - 0.00058 20.0 19.0 0.00058 20.0 19.0 4.7 2 2 3 5 5 5 1 Tropomyosin like ATG16 PF08614.11 EAY00877.1 - 0.0031 17.8 18.1 0.0031 17.8 18.1 4.2 2 1 0 3 3 3 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAY00877.1 - 0.11 13.1 36.4 0.68 10.6 0.5 6.3 5 1 1 6 6 6 0 SlyX DUF4710 PF15828.5 EAY00877.1 - 0.63 10.2 9.1 1.3 9.2 4.8 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) FdhD-NarQ PF02634.15 EAY00877.1 - 6.9 6.3 7.0 0.93 9.1 2.3 2.0 2 0 0 2 2 2 0 FdhD/NarQ family Pkinase PF00069.25 EAY00878.1 - 1.8e-73 247.2 0.2 2.2e-73 246.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00878.1 - 6.3e-32 110.9 0.2 1.4e-31 109.8 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00878.1 - 2.4e-06 27.1 0.1 1.4e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAY00878.1 - 0.00049 19.1 0.6 0.00072 18.6 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain EMP70 PF02990.16 EAY00880.1 - 4e-57 194.1 32.2 5.1e-57 193.7 32.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 H_PPase PF03030.16 EAY00880.1 - 2.4 6.7 7.7 0.12 11.0 2.0 1.7 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase DUF21 PF01595.20 EAY00880.1 - 4.8 6.8 8.4 16 5.2 8.4 2.0 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain zf-C3HC4_3 PF13920.6 EAY00881.1 - 1.7e-13 50.2 11.3 2.5e-13 49.6 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAY00881.1 - 6.5e-06 26.4 13.5 1.2e-05 25.6 13.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EAY00881.1 - 0.0013 18.5 12.2 0.0026 17.6 12.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAY00881.1 - 0.11 12.4 14.3 0.22 11.4 14.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAY00881.1 - 0.41 10.6 14.4 0.29 11.1 12.8 1.6 1 1 1 2 2 2 0 zinc-RING finger domain MurB_C PF02873.16 EAY00883.1 - 0.069 13.2 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Apolipoprotein PF01442.18 EAY00884.1 - 7.3e-05 22.7 8.1 0.00018 21.4 8.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phage_min_cap2 PF06152.11 EAY00884.1 - 0.33 9.8 11.1 0.09 11.7 6.7 1.9 2 0 0 2 2 2 0 Phage minor capsid protein 2 PIN_8 PF18476.1 EAY00884.1 - 0.6 9.9 19.7 0.29 11.0 6.8 2.1 1 1 1 2 2 2 0 PIN like domain DUF2935 PF11155.8 EAY00884.1 - 1.2 9.4 8.0 0.32 11.3 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Val_tRNA-synt_C PF10458.9 EAY00884.1 - 3.2 8.1 11.3 9.9 6.5 0.1 3.5 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Lectin_N PF03954.14 EAY00884.1 - 5.5 6.7 14.8 0.71 9.6 1.1 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain RecG_N PF17190.4 EAY00884.1 - 6.9 7.5 14.7 0.33 11.7 2.5 2.7 2 2 1 3 3 3 0 RecG N-terminal helical domain Fzo_mitofusin PF04799.13 EAY00884.1 - 7.2 6.1 13.3 1 8.9 2.7 3.0 1 1 2 3 3 3 0 fzo-like conserved region Tropomyosin_1 PF12718.7 EAY00885.1 - 9.8e-07 29.0 14.2 9.8e-07 29.0 14.2 4.1 1 1 2 4 4 4 2 Tropomyosin like TPR_MLP1_2 PF07926.12 EAY00885.1 - 0.1 12.6 60.6 0.17 11.9 15.0 5.0 2 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EAY00885.1 - 0.2 12.3 43.2 0.38 11.4 0.6 7.3 2 1 4 6 6 6 0 SlyX APG6_N PF17675.1 EAY00885.1 - 2.2 8.8 63.7 0.17 12.4 7.2 4.5 2 1 1 3 3 3 0 Apg6 coiled-coil region AAA_13 PF13166.6 EAY00885.1 - 3.4 6.2 50.8 0.18 10.4 9.2 3.0 1 1 2 3 3 3 0 AAA domain Phage_GP20 PF06810.11 EAY00885.1 - 6.9 6.5 61.5 0.031 14.1 4.8 4.5 1 1 3 4 4 4 0 Phage minor structural protein GP20 Viral_P18 PF04521.13 EAY00885.1 - 8.4 6.2 9.4 1.4 8.7 3.3 2.7 1 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF768 PF05589.11 EAY00886.1 - 0.054 13.5 2.2 0.19 11.8 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF768) MiaE_2 PF13794.6 EAY00886.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like bZIP_2 PF07716.15 EAY00886.1 - 0.17 12.0 0.1 0.17 12.0 0.1 5.1 6 1 0 6 6 6 0 Basic region leucine zipper YabA PF06156.13 EAY00886.1 - 0.29 11.8 29.9 6.9 7.4 2.4 4.3 2 1 1 4 4 4 0 Initiation control protein YabA bZIP_1 PF00170.21 EAY00886.1 - 1.5 9.0 20.4 4.3 7.5 0.1 5.2 3 1 3 6 6 6 0 bZIP transcription factor APG6_N PF17675.1 EAY00886.1 - 2.2 8.8 28.1 1.4 9.4 2.5 4.0 1 1 3 4 4 4 0 Apg6 coiled-coil region CK_II_beta PF01214.18 EAY00887.1 - 5e-53 179.6 2.1 5.7e-53 179.4 2.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ArsA_ATPase PF02374.15 EAY00888.1 - 1.2e-79 267.7 1.6 5e-51 173.7 0.3 2.1 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 EAY00888.1 - 1.4e-13 51.1 0.6 1.6e-11 44.4 0.6 2.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EAY00888.1 - 6.9e-13 48.8 0.3 8e-11 42.1 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EAY00888.1 - 2.3e-06 27.2 3.0 1.2e-05 24.9 1.3 2.6 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EAY00888.1 - 2.7e-06 27.0 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EAY00888.1 - 1.4e-05 24.8 0.1 0.011 15.3 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EAY00888.1 - 6.9e-05 22.4 0.0 0.0004 19.9 0.0 2.1 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 EAY00888.1 - 0.00054 19.3 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ PhoH PF02562.16 EAY00888.1 - 0.014 14.8 0.0 0.091 12.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EAY00888.1 - 0.018 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAY00888.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 EAY00888.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EAY00888.1 - 0.067 12.8 0.4 0.17 11.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EAY00888.1 - 0.11 11.8 0.1 1 8.6 0.1 2.1 2 0 0 2 2 2 0 VirC1 protein zf-C2H2_4 PF13894.6 EAY00888.1 - 0.17 12.8 0.4 0.71 10.9 0.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Ank_2 PF12796.7 EAY00889.1 - 8.3e-98 321.1 25.4 1.1e-16 61.1 0.2 14.9 5 5 10 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00889.1 - 7.2e-75 246.5 24.5 7.4e-08 32.8 0.5 18.8 12 4 8 20 20 20 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00889.1 - 1.5e-72 238.7 21.1 2.1e-07 31.0 0.0 17.1 13 3 6 19 19 19 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00889.1 - 4e-64 205.0 34.6 4.1e-05 23.6 0.0 24.7 28 0 0 28 28 28 14 Ankyrin repeat Ank PF00023.30 EAY00889.1 - 6.8e-55 181.3 17.9 3.6e-05 24.0 0.2 19.6 20 0 0 20 20 20 10 Ankyrin repeat Ribosomal_L32e PF01655.18 EAY00890.1 - 1e-35 122.4 0.0 1.2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L32e PF01655.18 EAY00891.1 - 5.1e-32 110.5 0.0 6.3e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L32e PF01655.18 EAY00892.1 - 1e-35 122.4 0.0 1.2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Maf PF02545.14 EAY00893.1 - 1.2e-49 168.4 0.0 1.4e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Piwi PF02171.17 EAY00894.1 - 0.0066 15.7 0.7 0.0066 15.7 0.7 1.2 1 0 0 1 1 1 1 Piwi domain DUF5600 PF18150.1 EAY00895.1 - 0.019 15.6 1.8 0.39 11.3 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5600) Mem_trans PF03547.18 EAY00897.1 - 1.3e-13 50.1 0.0 2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Membrane transport protein Pes-10 PF07149.11 EAY00897.1 - 0.26 10.3 8.4 0.39 9.7 8.4 1.2 1 0 0 1 1 1 0 Pes-10 Raftlin PF15250.6 EAY00897.1 - 0.96 8.1 3.6 1.4 7.6 3.6 1.1 1 0 0 1 1 1 0 Raftlin Ank_2 PF12796.7 EAY00898.1 - 0.00047 20.7 0.0 0.00055 20.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00898.1 - 0.00073 19.9 0.1 0.036 14.5 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAY00898.1 - 0.0087 16.6 0.0 0.0094 16.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY00898.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CAP PF00188.26 EAY00899.1 - 5.9e-18 65.9 0.0 2.4e-06 28.4 0.0 3.3 3 0 0 3 3 3 3 Cysteine-rich secretory protein family SYS1 PF09801.9 EAY00900.1 - 6.3e-13 49.1 2.1 7.1e-13 48.9 2.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Peptidase_U4 PF03419.13 EAY00900.1 - 0.00014 21.3 0.4 0.00015 21.2 0.4 1.0 1 0 0 1 1 1 1 Sporulation factor SpoIIGA EF-hand_7 PF13499.6 EAY00901.1 - 1.9e-14 53.9 0.0 1.5e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAY00901.1 - 6.7e-13 47.4 0.0 0.01 15.7 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EAY00901.1 - 3.5e-10 38.7 0.0 0.00041 19.7 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EAY00901.1 - 1.6e-07 31.0 0.0 0.0084 15.9 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 EAY00901.1 - 0.00011 22.4 0.0 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 EAY00901.1 - 0.0016 18.7 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DUF2666 PF10869.8 EAY00901.1 - 0.015 15.5 0.3 0.19 12.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF2095 PF09868.9 EAY00901.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) EF-hand_5 PF13202.6 EAY00901.1 - 0.21 11.1 0.9 9.4 5.9 0.0 2.7 2 0 0 2 2 2 0 EF hand Cyclin_N PF00134.23 EAY00902.1 - 3e-22 78.7 0.1 5.9e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAY00902.1 - 2.2e-19 69.7 0.1 1e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-C2H2_2 PF12756.7 EAY00903.1 - 0.00042 20.6 1.7 0.00082 19.7 1.7 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 EAY00903.1 - 0.012 15.6 2.8 0.086 12.8 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain OrsD PF12013.8 EAY00903.1 - 0.22 12.0 3.3 0.51 10.8 3.3 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D HlyE PF06109.13 EAY00905.1 - 0.047 13.0 0.1 0.06 12.6 0.1 1.3 1 1 0 1 1 1 0 Haemolysin E (HlyE) dNK PF01712.19 EAY00906.1 - 1.8e-20 73.7 3.9 1.7e-09 37.8 1.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 EAY00906.1 - 5.5e-11 43.1 0.2 1.7e-09 38.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EAY00906.1 - 8.7e-05 22.7 0.7 0.096 12.8 0.1 2.8 1 1 1 3 3 3 2 Shikimate kinase AAA_33 PF13671.6 EAY00906.1 - 0.0013 18.9 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain WES_acyltransf PF03007.16 EAY00906.1 - 0.0023 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Thymidylate_kin PF02223.17 EAY00906.1 - 0.0048 16.6 0.7 0.062 13.0 0.1 2.4 2 1 0 2 2 2 1 Thymidylate kinase Rad17 PF03215.15 EAY00906.1 - 0.0051 16.7 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EAY00906.1 - 0.017 15.6 0.4 0.2 12.1 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EAY00906.1 - 0.018 15.0 0.4 0.028 14.3 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EAY00906.1 - 0.032 14.2 0.0 0.081 12.9 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EAY00906.1 - 0.035 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EAY00906.1 - 0.036 13.8 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 EAY00906.1 - 0.051 14.1 0.2 0.11 13.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 EAY00906.1 - 0.064 13.4 1.0 1.6 8.9 0.1 2.3 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_22 PF13401.6 EAY00906.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EAY00906.1 - 0.096 12.6 0.4 0.55 10.1 0.1 2.3 2 1 1 3 3 3 0 NTPase APS_kinase PF01583.20 EAY00906.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 EAY00906.1 - 0.16 12.4 0.2 8.8 6.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Vta1 PF04652.16 EAY00908.1 - 0.023 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.29 EAY00909.1 - 2.6e-05 24.1 0.2 0.088 12.6 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase dNK PF01712.19 EAY00910.1 - 9.8e-22 77.8 4.0 6.4e-19 68.6 4.0 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EAY00910.1 - 5.7e-12 46.3 0.2 1.7e-10 41.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EAY00910.1 - 3.3e-06 27.3 0.9 0.097 12.8 0.1 2.7 1 1 2 3 3 3 2 Shikimate kinase AAA_33 PF13671.6 EAY00910.1 - 1.5e-05 25.2 0.0 0.078 13.1 0.0 2.2 2 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 EAY00910.1 - 0.00028 20.6 0.7 0.064 12.9 0.1 2.5 2 1 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.6 EAY00910.1 - 0.00042 20.6 0.0 0.00078 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAY00910.1 - 0.00043 20.2 0.1 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 EAY00910.1 - 0.00046 20.5 0.0 0.0008 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAY00910.1 - 0.00057 20.3 0.4 0.0061 17.0 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAY00910.1 - 0.00057 20.4 0.3 0.0011 19.5 0.2 1.7 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 EAY00910.1 - 0.00084 19.3 0.7 0.0011 19.0 0.2 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EAY00910.1 - 0.0013 18.5 0.2 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_14 PF13173.6 EAY00910.1 - 0.0022 18.1 0.7 0.0075 16.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain WES_acyltransf PF03007.16 EAY00910.1 - 0.0024 17.7 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AAA_16 PF13191.6 EAY00910.1 - 0.0034 17.8 0.0 0.0059 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EAY00910.1 - 0.0043 17.4 0.3 0.019 15.3 0.1 2.1 1 1 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 EAY00910.1 - 0.0048 16.8 0.4 0.028 14.3 0.1 2.3 2 1 0 2 2 2 1 NTPase TsaE PF02367.17 EAY00910.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EAY00910.1 - 0.0062 17.0 0.3 0.28 11.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EAY00910.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.18 EAY00910.1 - 0.012 15.4 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EAY00910.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 EAY00910.1 - 0.015 15.4 1.1 0.34 11.0 0.1 2.3 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.6 EAY00910.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAY00910.1 - 0.026 13.6 0.1 0.051 12.6 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Guanylate_kin PF00625.21 EAY00910.1 - 0.033 13.9 0.3 6 6.5 0.0 2.6 2 1 0 2 2 2 0 Guanylate kinase NACHT PF05729.12 EAY00910.1 - 0.043 13.7 0.0 0.079 12.9 0.0 1.6 1 1 0 1 1 1 0 NACHT domain CoaE PF01121.20 EAY00910.1 - 0.055 13.1 0.2 0.13 12.0 0.1 1.9 2 1 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.12 EAY00910.1 - 0.06 12.6 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EAY00910.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EAY00910.1 - 0.091 13.3 2.1 0.21 12.1 2.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAY00910.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAY00910.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ank_2 PF12796.7 EAY00911.1 - 2.7e-26 91.9 0.0 3.1e-11 43.7 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY00911.1 - 1e-20 73.8 0.0 2.3e-13 50.4 0.0 4.7 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00911.1 - 2.7e-18 64.2 0.1 0.0018 18.6 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAY00911.1 - 1e-14 54.4 0.2 7.6e-07 29.3 0.0 5.4 3 2 4 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY00911.1 - 1.8e-13 50.2 0.2 1.1e-05 25.6 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 EAY00911.1 - 3.8e-05 23.6 0.5 0.00033 20.6 0.4 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Guanylate_cyc PF00211.20 EAY00912.1 - 2.8e-40 137.9 0.0 5.8e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY00912.1 - 3.6e-14 52.9 0.1 1.1e-13 51.4 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAY00912.1 - 1.7e-10 40.9 0.0 5.1e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EAY00912.1 - 0.00015 22.0 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EAY00912.1 - 0.0079 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAY00912.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain HNOBA PF07701.14 EAY00912.1 - 0.073 12.5 0.1 0.21 11.0 0.1 1.8 1 0 0 1 1 1 0 Heme NO binding associated Shisa PF13908.6 EAY00912.1 - 0.17 12.1 0.6 7.5 6.7 0.1 2.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator HTH_36 PF13730.6 EAY00916.1 - 0.023 14.7 0.2 0.099 12.6 0.2 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain EphA2_TM PF14575.6 EAY00917.1 - 0.0028 18.5 0.5 0.0049 17.7 0.5 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2140 PF09911.9 EAY00917.1 - 0.0045 16.6 2.1 1.3 8.5 0.2 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2140) FAM176 PF14851.6 EAY00917.1 - 0.02 14.6 0.2 0.037 13.7 0.2 1.4 1 0 0 1 1 1 0 FAM176 family Shisa PF13908.6 EAY00917.1 - 0.04 14.2 0.4 0.067 13.4 0.4 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EAY00917.1 - 0.042 14.1 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) UPF0016 PF01169.19 EAY00917.1 - 0.046 14.0 0.3 0.095 13.0 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 DUF5305 PF17231.2 EAY00917.1 - 0.063 12.7 2.0 0.084 12.3 0.2 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5305) Protocadherin PF08374.11 EAY00917.1 - 0.071 13.1 5.8 0.098 12.6 4.7 1.7 1 1 1 2 2 2 0 Protocadherin Prominin PF05478.11 EAY00917.1 - 0.33 8.8 3.5 0.11 10.5 0.7 1.5 2 0 0 2 2 2 0 Prominin Pkinase PF00069.25 EAY00919.1 - 2e-24 86.4 0.0 2.7e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00919.1 - 6.5e-11 42.0 0.0 1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAY00919.1 - 2.6e-06 26.5 0.1 3.5e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase MULE PF10551.9 EAY00920.1 - 6.2e-10 39.4 0.1 1.5e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAY00920.1 - 0.015 14.2 0.2 0.03 13.2 0.2 1.5 1 0 0 1 1 1 0 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAY00920.1 - 0.016 14.9 0.1 0.057 13.1 0.1 1.8 1 1 1 2 2 2 0 Transposase FAR1 PF03101.15 EAY00920.1 - 0.095 13.4 0.1 0.22 12.3 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain PapD_N PF00345.20 EAY00921.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAY00923.1 - 7.5e-17 61.3 2.6 8.6e-17 61.1 2.6 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF3839 PF12943.7 EAY00924.1 - 6.7e-154 510.3 12.5 8.3e-154 510.0 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY00924.1 - 0.018 15.5 0.7 0.077 13.4 0.1 1.9 2 0 0 2 2 2 0 Fez1 KELK PF15796.5 EAY00924.1 - 0.052 14.0 5.0 0.53 10.8 0.1 3.1 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1731 PF08338.11 EAY00925.1 - 0.23 11.3 0.1 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) DUF4107 PF13389.6 EAY00926.1 - 2.3e-70 235.9 4.8 3.1e-70 235.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) UPF0184 PF03670.13 EAY00927.1 - 0.0074 16.7 3.5 0.02 15.2 0.4 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0184) FANCI_S2 PF14676.6 EAY00927.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.3 1 1 0 1 1 1 0 FANCI solenoid 2 Mucin PF01456.17 EAY00927.1 - 0.33 10.9 5.3 0.44 10.5 5.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4083 PF13314.6 EAY00927.1 - 0.4 10.7 2.6 7.2 6.6 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4083) Snapin_Pallidin PF14712.6 EAY00927.1 - 0.44 11.0 6.9 0.41 11.1 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 EAY00927.1 - 0.74 10.3 7.5 0.73 10.4 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 EAY00927.1 - 0.77 10.3 6.3 4.9 7.7 1.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LRR_4 PF12799.7 EAY00928.1 - 4.4e-13 49.2 12.4 2.1e-06 27.9 1.1 4.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAY00928.1 - 8.3e-07 28.7 2.0 7.8e-06 25.6 1.2 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 EAY00928.1 - 0.02 14.4 0.4 0.035 13.6 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EAY00928.1 - 0.076 13.1 0.5 30 5.0 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EAY00928.1 - 0.11 13.2 1.9 25 5.9 0.2 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EAY00929.1 - 5.3e-29 99.8 56.8 8.6e-08 31.8 3.1 9.7 9 0 0 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 EAY00929.1 - 7.5e-24 83.4 100.8 1e-05 25.8 2.5 14.0 11 3 4 16 16 16 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY00929.1 - 1.1e-19 70.6 47.6 0.00028 20.4 0.5 8.6 7 1 0 8 8 8 7 Leucine-rich repeat LRR_1 PF00560.33 EAY00929.1 - 0.04 14.4 58.4 5.7 7.9 0.4 14.6 12 2 0 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 EAY00929.1 - 0.11 12.6 62.2 0.9 9.8 0.0 14.2 16 0 0 16 16 16 0 Leucine Rich repeat EphA2_TM PF14575.6 EAY00929.1 - 0.14 13.0 0.1 3.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 EAY00929.1 - 7.4 6.2 8.5 0.36 10.5 1.5 2.4 3 0 0 3 3 3 0 FAM176 family Pkinase PF00069.25 EAY00930.1 - 9.6e-59 198.9 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY00930.1 - 6.1e-34 117.5 0.0 7.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY00930.1 - 4.4e-07 29.5 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Clathrin PF00637.20 EAY00930.1 - 0.021 14.7 0.4 0.072 13.0 0.4 1.9 1 1 0 1 1 1 0 Region in Clathrin and VPS Haspin_kinase PF12330.8 EAY00930.1 - 0.037 13.0 0.1 0.075 12.0 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EAY00930.1 - 0.16 11.3 0.1 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RasGAP PF00616.19 EAY00931.1 - 0.00074 19.3 4.6 0.001 18.8 4.6 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase MutS_III PF05192.18 EAY00931.1 - 0.37 11.0 2.8 0.48 10.6 2.8 1.3 1 0 0 1 1 1 0 MutS domain III Exonuc_VII_L PF02601.15 EAY00931.1 - 0.58 9.7 7.2 0.8 9.2 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Retrotrans_gag PF03732.17 EAY00931.1 - 0.79 10.0 7.8 5.6 7.3 0.2 3.3 1 1 2 3 3 3 0 Retrotransposon gag protein AAA_11 PF13086.6 EAY00931.1 - 0.97 9.2 10.6 0.9 9.3 9.6 1.3 1 1 0 1 1 1 0 AAA domain LMBR1 PF04791.16 EAY00931.1 - 1.6 7.5 3.3 1.8 7.4 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ZnuA PF01297.17 EAY00931.1 - 8.8 5.6 8.7 18 4.6 8.7 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Kelch_6 PF13964.6 EAY00932.1 - 7.6e-07 29.2 7.4 1.2 9.5 0.1 5.3 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EAY00932.1 - 8.3e-07 28.9 4.6 0.14 12.2 0.1 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EAY00932.1 - 1.2e-05 25.1 0.5 5.5 7.1 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EAY00932.1 - 4.3e-05 23.7 2.8 0.3 11.4 0.1 3.6 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EAY00932.1 - 6.7e-05 22.4 2.2 1.9 8.1 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EAY00932.1 - 0.18 11.8 2.9 19 5.3 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Anthrax_toxA PF03497.16 EAY00933.1 - 1.1 9.4 8.9 0.5 10.5 2.7 2.4 2 0 0 2 2 2 0 Anthrax toxin LF subunit SPOUT_MTase PF02590.17 EAY00933.1 - 8.3 6.4 10.7 3.3 7.7 2.6 2.7 3 0 0 3 3 3 0 Predicted SPOUT methyltransferase Laminin_II PF06009.12 EAY00933.1 - 9 6.3 20.2 0.023 14.7 8.2 2.4 2 1 0 2 2 2 0 Laminin Domain II Homeobox_KN PF05920.11 EAY00934.1 - 5.9e-16 58.1 0.2 1.2e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAY00934.1 - 3.4e-10 39.6 1.2 5.7e-10 38.9 1.2 1.4 1 0 0 1 1 1 1 Homeodomain Syntaxin-18_N PF10496.9 EAY00934.1 - 0.26 11.6 5.5 0.12 12.7 1.4 2.3 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Tho2 PF11262.8 EAY00935.1 - 1.2e-19 70.7 3.5 1.2e-19 70.7 3.5 3.3 1 1 2 3 3 3 1 Transcription factor/nuclear export subunit protein 2 IFT20 PF14931.6 EAY00935.1 - 0.087 13.0 8.7 0.38 10.9 8.7 2.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 LRR_5 PF13306.6 EAY00936.1 - 2.9e-39 133.9 18.0 3.3e-22 78.8 8.6 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00936.1 - 3.9e-06 26.5 1.2 0.16 11.8 0.1 4.6 3 2 2 5 5 5 3 Leucine rich repeat PI-PLC-X PF00388.19 EAY00936.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain LegC3_N PF18654.1 EAY00937.1 - 0.001 18.4 14.8 0.001 18.4 14.8 2.0 1 1 1 2 2 2 1 LegC3 N-terminal coiled-coil domain Tektin PF03148.14 EAY00937.1 - 0.15 10.8 31.9 0.62 8.7 2.5 3.0 1 1 2 3 3 3 0 Tektin family ATG16 PF08614.11 EAY00937.1 - 0.2 11.8 37.2 0.27 11.4 30.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 EAY00937.1 - 0.37 11.1 37.9 0.6 10.5 3.1 5.3 1 1 4 5 5 5 0 Csm1 N-terminal domain DUF724 PF05266.14 EAY00937.1 - 0.74 9.6 39.8 0.17 11.7 17.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) MAD PF05557.13 EAY00937.1 - 1.4 7.2 39.1 1.8 6.8 39.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Fib_alpha PF08702.10 EAY00937.1 - 5.1 7.3 36.9 0.63 10.2 11.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EAY00937.1 - 6.8 6.8 23.3 0.26 11.4 3.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) End3 PF12761.7 EAY00938.1 - 0.038 14.2 0.8 0.039 14.1 0.8 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 XhlA PF10779.9 EAY00938.1 - 0.1 12.8 0.3 0.15 12.3 0.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Rep_fac_C PF08542.11 EAY00940.1 - 0.11 13.0 0.2 0.62 10.5 0.0 2.3 2 1 0 2 2 2 0 Replication factor C C-terminal domain Sulfatase PF00884.23 EAY00941.1 - 4.9e-15 55.7 0.2 9.3e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Chromo PF00385.24 EAY00942.1 - 2.7 8.0 9.7 0.28 11.1 4.1 2.3 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Apolipoprotein PF01442.18 EAY00943.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MecA PF05389.12 EAY00945.1 - 0.0018 17.9 2.8 0.016 14.8 0.2 2.5 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) IL17_R_N PF15037.6 EAY00945.1 - 0.011 14.7 2.1 1.5 7.7 0.3 2.1 1 1 1 2 2 2 0 Interleukin-17 receptor extracellular region DUF4795 PF16043.5 EAY00945.1 - 0.024 14.2 17.0 0.079 12.6 1.0 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) Sec1 PF00995.23 EAY00947.1 - 3e-85 287.6 6.0 3.6e-85 287.3 6.0 1.1 1 0 0 1 1 1 1 Sec1 family Pkinase_Tyr PF07714.17 EAY00948.1 - 1.8e-29 102.8 0.0 2.9e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 EAY00948.1 - 2.4e-29 101.1 15.1 1.2e-06 28.9 0.5 6.7 7 0 0 7 7 7 5 Sel1 repeat Pkinase PF00069.25 EAY00948.1 - 2.1e-17 63.4 0.0 3.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF1462 PF07315.11 EAY00948.1 - 0.045 14.0 0.1 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) BAR PF03114.18 EAY00948.1 - 0.084 12.5 1.0 0.41 10.3 0.0 2.3 2 1 0 2 2 2 0 BAR domain TPR_8 PF13181.6 EAY00948.1 - 0.58 10.5 8.9 6.3 7.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HOASN PF14515.6 EAY00948.1 - 1.4 9.4 6.0 1.7 9.0 0.5 3.1 3 0 0 3 3 3 0 Haem-oxygenase-associated N-terminal helices FRB_dom PF08771.11 EAY00949.1 - 0.017 15.5 0.2 0.027 14.9 0.2 1.3 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain COX2_TM PF02790.15 EAY00950.1 - 0.048 13.8 0.2 0.048 13.8 0.2 4.1 4 1 1 5 5 5 0 Cytochrome C oxidase subunit II, transmembrane domain Ycf70 PF17382.2 EAY00950.1 - 0.22 12.0 0.1 0.22 12.0 0.1 3.1 2 0 0 2 2 2 0 Uncharacterized Ycf70-like HAD_2 PF13419.6 EAY00951.1 - 0.011 15.8 1.5 0.015 15.4 1.5 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Lebercilin PF15619.6 EAY00951.1 - 0.086 12.5 0.1 0.45 10.2 0.1 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Ank_2 PF12796.7 EAY00952.1 - 1e-12 48.4 0.0 9.2e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY00952.1 - 5.5e-11 42.4 0.0 2.8e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY00952.1 - 3.4e-10 40.0 0.0 2.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY00952.1 - 7.4e-09 36.0 0.0 3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY00952.1 - 2.3e-07 30.5 0.0 0.0035 17.7 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat DUF3083 PF11281.8 EAY00952.1 - 0.025 14.0 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) AAA PF00004.29 EAY00954.1 - 1.9e-18 67.2 0.1 8.2e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAY00954.1 - 5.6e-06 26.4 0.1 2.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAY00954.1 - 6.6e-06 26.6 0.9 0.0036 17.7 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAY00954.1 - 0.0012 19.1 0.1 0.011 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAY00954.1 - 0.0019 17.9 1.0 0.086 12.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.6 EAY00954.1 - 0.0026 18.3 0.0 0.0026 18.3 0.0 3.4 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EAY00954.1 - 0.0044 17.4 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EAY00954.1 - 0.0067 16.4 2.8 0.2 11.5 0.1 3.4 2 1 1 3 3 3 1 NACHT domain AAA_33 PF13671.6 EAY00954.1 - 0.0094 16.1 0.3 0.23 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EAY00954.1 - 0.023 13.7 0.2 0.055 12.5 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EAY00954.1 - 0.025 14.3 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EAY00954.1 - 0.041 13.8 0.2 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 EAY00954.1 - 0.043 13.7 0.0 0.043 13.7 0.0 3.2 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_lid_3 PF17862.1 EAY00954.1 - 0.055 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA+ lid domain RuvB_N PF05496.12 EAY00954.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EAY00954.1 - 0.084 12.1 0.1 0.084 12.1 0.1 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_5 PF07728.14 EAY00954.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EAY00954.1 - 0.12 12.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EAY00954.1 - 0.19 11.6 3.7 0.18 11.7 0.2 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain tRNA_lig_kinase PF08303.11 EAY00954.1 - 0.68 10.0 6.1 3.1 7.9 0.0 3.9 2 1 0 3 3 3 0 tRNA ligase kinase domain AAA_18 PF13238.6 EAY00954.1 - 0.94 10.0 0.0 0.94 10.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EAY00954.1 - 7.1 7.2 6.6 0.7 10.4 0.5 2.4 2 1 0 2 2 2 0 ABC transporter HALZ PF02183.18 EAY00955.1 - 0.00071 19.7 2.2 0.00071 19.7 2.2 4.0 5 0 0 5 5 5 1 Homeobox associated leucine zipper DUF1722 PF08349.11 EAY00955.1 - 0.054 13.8 9.8 0.064 13.5 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) CDT1_C PF16679.5 EAY00955.1 - 0.7 10.4 10.0 14 6.2 3.0 4.4 3 2 1 4 4 4 0 DNA replication factor Cdt1 C-terminal domain DUF948 PF06103.11 EAY00955.1 - 7.8 6.8 6.9 1.4 9.2 0.3 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Phos_pyr_kin PF08543.12 EAY00956.1 - 2.7e-16 59.7 0.0 3.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EAY00956.1 - 2.8e-08 33.5 0.0 5e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ras PF00071.22 EAY00957.1 - 3.6e-37 127.5 0.0 4.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY00957.1 - 8e-26 90.6 0.0 1.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY00957.1 - 2.6e-14 53.0 0.0 3.8e-14 52.5 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAY00957.1 - 3.6e-06 26.7 0.8 1.4e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAY00957.1 - 1.2e-05 25.3 0.7 0.012 15.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAY00957.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAY00957.1 - 0.0024 17.3 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAY00957.1 - 0.0038 16.8 0.1 0.27 10.7 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EAY00957.1 - 0.023 14.7 0.2 0.049 13.6 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3612 PF12268.8 EAY00958.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Histone PF00125.24 EAY00959.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAY00959.1 - 5.7e-17 61.2 0.7 5.7e-17 61.2 0.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAY00959.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fer4 PF00037.27 EAY00960.1 - 8.6e-12 44.4 17.1 1.8e-09 37.0 3.4 3.3 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EAY00960.1 - 5.2e-09 36.1 8.6 1.2e-08 34.9 8.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAY00960.1 - 1.7e-08 34.1 13.3 6.3e-07 29.2 2.4 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EAY00960.1 - 6e-08 32.3 13.5 7.3e-06 25.8 2.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EAY00960.1 - 1.9e-07 31.6 11.4 4.2e-07 30.5 11.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAY00960.1 - 3.1e-06 27.3 11.7 5.9e-06 26.4 10.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAY00960.1 - 6.1e-06 27.1 9.7 0.00025 21.9 1.0 2.7 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EAY00960.1 - 7.9e-05 23.0 7.3 0.0058 17.1 0.4 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAY00960.1 - 0.00013 22.0 14.3 0.0024 17.9 15.1 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAY00960.1 - 0.0023 18.3 3.7 0.0023 18.3 3.7 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_3 PF12798.7 EAY00960.1 - 0.0034 18.2 19.0 0.0043 17.9 5.8 2.9 2 0 0 2 2 2 1 4Fe-4S binding domain LZ3wCH PF18517.1 EAY00960.1 - 0.015 15.4 0.0 0.35 11.0 0.4 2.7 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Fer4_17 PF13534.6 EAY00960.1 - 0.088 13.4 16.2 13 6.4 15.4 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EAY00960.1 - 1.8 9.3 10.2 1.1 10.0 0.2 3.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 EAY00960.1 - 2.9 8.8 12.8 0.47 11.3 1.5 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 EAY00961.1 - 4.2e-16 59.0 1.6 2e-10 40.4 0.2 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EAY00961.1 - 7.9e-16 57.8 6.4 1.3e-15 57.1 6.4 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EAY00961.1 - 9.9e-11 41.7 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAY00961.1 - 1.1e-08 35.4 3.4 2.4e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAY00961.1 - 2e-08 33.9 0.1 0.00019 20.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EAY00961.1 - 2.8e-07 30.2 0.0 8.5e-07 28.6 0.0 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EAY00961.1 - 7e-07 28.7 0.0 1.6e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EAY00961.1 - 7.4e-07 28.2 0.2 1.1e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EAY00961.1 - 1.3e-06 28.3 0.1 2.1e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 EAY00961.1 - 3.5e-06 25.7 0.1 0.00068 18.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 EAY00961.1 - 3.7e-06 26.3 0.3 5.3e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EAY00961.1 - 3.8e-06 27.3 0.2 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EAY00961.1 - 1.1e-05 24.9 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EAY00961.1 - 1.7e-05 24.4 0.2 2.4e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EAY00961.1 - 3e-05 23.5 0.0 0.036 13.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EAY00961.1 - 0.00044 20.1 0.6 0.017 14.9 0.1 2.4 2 1 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_9 PF13454.6 EAY00961.1 - 0.00087 19.3 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EAY00961.1 - 0.0012 18.2 0.3 0.01 15.1 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EAY00961.1 - 0.0019 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EAY00961.1 - 0.0051 16.4 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EAY00961.1 - 0.017 15.2 0.1 5.4 7.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 EAY00961.1 - 0.018 15.1 0.0 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.15 EAY00961.1 - 0.031 14.2 0.1 0.074 12.9 0.0 1.7 2 1 0 2 2 1 0 YjeF-related protein N-terminus Trp_halogenase PF04820.14 EAY00961.1 - 0.031 13.1 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 EAY00961.1 - 0.053 13.4 0.1 0.053 13.4 0.1 1.5 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAY00961.1 - 0.089 13.1 0.5 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EAY00961.1 - 0.22 10.6 0.0 0.58 9.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3800 PF12686.7 EAY00962.1 - 0.082 13.5 2.5 1.8 9.2 2.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) PMC2NT PF08066.12 EAY00962.1 - 0.11 13.2 5.8 0.32 11.7 5.8 1.7 1 0 0 1 1 1 0 PMC2NT (NUC016) domain FapA PF03961.13 EAY00962.1 - 0.12 11.0 26.6 0.06 11.9 6.3 3.0 2 1 1 3 3 3 0 Flagellar Assembly Protein A Sec8_exocyst PF04048.14 EAY00962.1 - 0.23 11.3 13.2 0.032 14.1 3.1 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Syntaxin-6_N PF09177.11 EAY00962.1 - 0.38 11.3 16.4 7.8 7.1 4.6 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 EAY00962.1 - 0.45 10.6 28.2 0.073 13.1 10.2 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 EAY00962.1 - 0.45 9.4 11.1 0.58 9.0 11.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1241 PF06840.11 EAY00962.1 - 0.46 10.1 11.4 0.51 10.0 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) TPK_catalytic PF04263.16 EAY00962.1 - 0.5 10.4 2.7 1.2 9.3 2.7 1.8 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PRKG1_interact PF15898.5 EAY00962.1 - 0.93 10.4 30.0 4.1 8.4 7.2 3.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain COG2 PF06148.11 EAY00962.1 - 1.3 9.1 19.6 0.64 10.1 1.6 3.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Swi5 PF07061.11 EAY00962.1 - 2.7 8.1 21.6 4 7.6 4.1 4.4 3 1 0 3 3 3 0 Swi5 Herpes_UL6 PF01763.16 EAY00962.1 - 4 5.8 14.3 0.048 12.2 4.0 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like FAM184 PF15665.5 EAY00962.1 - 4.7 6.9 27.0 0.047 13.5 9.5 2.9 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DUF948 PF06103.11 EAY00962.1 - 5.1 7.4 6.8 0.84 9.9 0.3 2.8 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 EAY00962.1 - 5.6 6.0 23.0 12 4.8 19.1 2.5 2 1 0 2 2 2 0 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 EAY00962.1 - 6.1 6.9 9.8 1.9 8.5 1.7 2.5 2 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 EAY00962.1 - 8.8 5.8 32.4 1.1 8.7 15.6 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Gly-zipper_Omp PF13488.6 EAY00963.1 - 0.00083 19.3 8.3 0.0012 18.8 8.3 1.2 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAY00963.1 - 0.1 11.8 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase Gly-zipper_OmpA PF13436.6 EAY00963.1 - 0.11 12.3 8.1 0.22 11.4 8.1 1.5 1 0 0 1 1 1 0 Glycine-zipper domain DUF1269 PF06897.12 EAY00963.1 - 0.12 12.6 5.0 0.21 11.9 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY00963.1 - 0.89 9.7 4.9 1.4 9.0 4.9 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAY00965.1 - 7.9e-05 22.2 3.5 0.00014 21.4 3.5 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY00965.1 - 0.006 16.6 0.9 0.013 15.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAY00965.1 - 0.0098 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAY00965.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Tcf25 PF04910.14 EAY00967.1 - 0.03 13.4 0.3 0.037 13.1 0.3 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 EpuA PF11772.8 EAY00967.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4795 PF16043.5 EAY00967.1 - 0.65 9.6 27.0 3.2 7.3 0.8 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) PTR PF12789.7 EAY00967.1 - 0.92 9.6 9.7 0.61 10.2 2.2 4.1 3 1 0 3 3 3 0 Phage tail repeat like DUF5623 PF18536.1 EAY00968.1 - 0.091 13.1 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Spo12 PF05032.12 EAY00968.1 - 0.4 10.6 8.3 0.15 12.0 2.9 2.4 3 0 0 3 3 3 0 Spo12 family IFT57 PF10498.9 EAY00969.1 - 4e-99 332.0 4.2 4.6e-99 331.8 4.2 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EAY00969.1 - 0.0017 18.4 11.4 0.0069 16.4 11.4 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus GLTP PF08718.11 EAY00969.1 - 0.011 16.1 1.8 0.018 15.3 1.8 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Nup188 PF10487.9 EAY00969.1 - 0.032 12.2 7.1 0.044 11.7 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF4201 PF13870.6 EAY00969.1 - 0.036 13.8 11.6 0.077 12.7 11.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) ApoLp-III PF07464.11 EAY00969.1 - 0.036 14.1 11.8 0.23 11.6 9.1 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Collagen_mid PF15984.5 EAY00969.1 - 0.04 13.7 0.1 0.74 9.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial collagen, middle region AAA_23 PF13476.6 EAY00969.1 - 0.054 14.0 5.9 0.09 13.3 5.9 1.3 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EAY00969.1 - 0.055 12.3 11.1 0.11 11.4 11.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 EAY00969.1 - 0.1 11.2 10.0 0.12 10.9 10.0 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EAY00969.1 - 0.14 12.2 14.0 0.063 13.3 6.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EAY00969.1 - 0.14 12.2 7.0 3.7 7.6 4.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mod_r PF07200.13 EAY00969.1 - 0.22 11.6 10.6 0.47 10.5 10.6 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Nup54 PF13874.6 EAY00969.1 - 0.37 10.9 5.5 1.2 9.2 5.5 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 EAY00969.1 - 0.47 10.5 9.8 1.2 9.2 5.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 EAY00969.1 - 0.55 10.3 12.3 0.46 10.6 10.1 1.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 EAY00969.1 - 1 10.1 9.7 1.4 9.7 5.8 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF5344 PF17279.2 EAY00969.1 - 1.5 9.4 11.1 4.4 8.0 0.1 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5344) BLOC1_2 PF10046.9 EAY00969.1 - 3.5 8.0 12.9 52 4.2 0.1 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 EAY00969.1 - 4.5 7.6 9.6 11 6.3 1.0 3.3 1 1 3 4 4 4 0 ABC transporter C-terminal domain TMPIT PF07851.13 EAY00969.1 - 8.3 5.6 9.1 4.6 6.4 6.5 1.7 1 1 1 2 2 2 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EAY00970.1 - 0.00089 18.9 10.6 0.00089 18.9 10.6 2.5 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EAY00970.1 - 0.46 9.8 11.0 2.4 7.4 9.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IFT57 PF10498.9 EAY00970.1 - 0.51 9.3 24.9 0.034 13.1 12.7 2.8 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 CdvA PF18822.1 EAY00970.1 - 0.68 9.8 18.9 0.77 9.6 0.0 3.7 4 1 0 4 4 4 0 CdvA-like coiled-coil domain Occludin_ELL PF07303.13 EAY00970.1 - 1.6 9.5 18.4 0.25 12.1 0.5 4.2 3 2 1 4 4 4 0 Occludin homology domain Fib_alpha PF08702.10 EAY00970.1 - 2.7 8.2 22.7 0.36 11.0 1.6 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 EAY00970.1 - 5.3 7.4 12.0 4.4 7.6 4.9 3.8 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 EAY00970.1 - 6 6.9 18.8 5.8 7.0 0.0 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ZapD PF07072.11 EAY00970.1 - 7.7 6.2 11.9 0.59 9.9 3.3 2.8 2 1 1 3 3 3 0 Cell division protein Exonuc_VII_L PF02601.15 EAY00970.1 - 8.2 5.9 15.5 22 4.5 14.8 2.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 EAY00970.1 - 9.5 6.8 28.6 0.99 9.9 4.1 3.8 2 1 2 4 4 4 0 Protein of unknown function DUF16 PSP PF04046.16 EAY00971.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY00972.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY00973.1 - 0.019 15.4 0.5 0.039 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY00974.1 - 1.2e-24 86.1 11.7 1.2e-24 86.1 11.7 4.6 5 1 0 5 5 5 1 Phage tail repeat like T5orf172 PF10544.9 EAY00975.1 - 2.3e-06 28.1 0.1 4.9e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY00975.1 - 0.025 14.4 1.7 0.073 12.9 0.7 2.2 2 1 0 2 2 2 0 KilA-N domain Pox_A32 PF04665.12 EAY00976.1 - 5.6e-07 29.3 2.5 5.6e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00976.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY00976.1 - 5.2e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY00976.1 - 0.00012 22.1 2.8 0.00026 21.1 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00976.1 - 0.00058 19.7 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00976.1 - 0.0011 18.8 0.5 0.0022 17.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00976.1 - 0.0019 17.9 0.5 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00976.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAY00976.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAY00976.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00976.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAY00976.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY00976.1 - 0.3 11.3 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2897 PF11446.8 EAY00977.1 - 1.2 9.1 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4108 PF13390.6 EAY00978.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Phage_spike_2 PF18781.1 EAY00979.1 - 0.079 13.0 0.7 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Phage spike trimer DIM1 PF02966.16 EAY00980.1 - 0.26 11.1 2.0 1.1 9.0 0.6 2.0 1 1 1 2 2 2 0 Mitosis protein DIM1 DUF563 PF04577.14 EAY00981.1 - 6.5e-19 68.9 0.0 9.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PPIP5K2_N PF18086.1 EAY00981.1 - 0.1 12.8 0.3 0.25 11.5 0.3 1.6 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Methyltransf_11 PF08241.12 EAY00982.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAY00982.1 - 1.1e-17 64.5 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAY00982.1 - 4.8e-15 55.7 0.0 6.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAY00982.1 - 9.6e-10 39.1 0.0 1.5e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAY00982.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAY00982.1 - 2.5e-08 33.5 0.1 3.9e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 EAY00982.1 - 1.7e-05 24.6 0.0 7.3e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 EAY00982.1 - 2.5e-05 23.8 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EAY00982.1 - 0.00033 20.3 0.0 0.00042 20.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 EAY00982.1 - 0.00061 19.1 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 EAY00982.1 - 0.0021 17.2 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 EAY00982.1 - 0.0058 15.2 0.0 0.007 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EAY00982.1 - 0.0068 15.8 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EAY00982.1 - 0.012 14.7 0.1 0.047 12.8 0.1 1.9 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_9 PF08003.11 EAY00982.1 - 0.014 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 EAY00982.1 - 0.057 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase UQ_con PF00179.26 EAY00984.1 - 3.8e-43 146.5 0.1 4.4e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAY00984.1 - 5.5e-05 22.9 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 EAY00984.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 DUF4817 PF16087.5 EAY00984.1 - 0.12 12.2 0.3 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Cofilin_ADF PF00241.20 EAY00985.1 - 4.1e-09 36.3 0.0 4.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Drf_GBD PF06371.13 EAY00986.1 - 0.023 14.3 1.5 0.026 14.1 1.5 1.2 1 1 0 1 1 1 0 Diaphanous GTPase-binding Domain LRR_5 PF13306.6 EAY00987.1 - 2.6e-32 111.5 30.9 1.6e-19 70.1 6.2 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00987.1 - 1.2e-05 24.9 4.2 0.32 10.8 0.1 4.5 3 2 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EAY00987.1 - 0.14 12.7 3.9 21 5.7 0.0 3.8 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) DUF4108 PF13390.6 EAY00988.1 - 5.9e-65 217.5 6.2 6.6e-65 217.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Pox_A32 PF04665.12 EAY00990.1 - 3.4e-07 30.0 2.6 3.4e-07 30.0 2.6 1.9 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY00990.1 - 2.8e-05 24.4 0.2 0.00021 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY00990.1 - 5e-05 23.1 0.2 0.34 10.6 0.1 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY00990.1 - 0.00011 22.2 2.7 0.00027 21.0 2.8 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY00990.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY00990.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY00990.1 - 0.0013 18.4 0.5 0.009 15.7 0.2 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY00990.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain Elong_Iki1 PF10483.9 EAY00990.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_25 PF13481.6 EAY00990.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY00990.1 - 0.089 13.2 0.1 0.73 10.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAY00990.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY00990.1 - 0.3 11.4 3.7 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) PSP PF04046.16 EAY00993.1 - 0.072 13.0 0.8 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP LRR_5 PF13306.6 EAY00994.1 - 1.5e-198 648.9 116.6 1.1e-45 154.7 19.5 6.7 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY00994.1 - 2.9e-46 155.1 0.0 0.0003 20.5 0.0 12.6 2 1 12 14 14 14 13 Leucine rich repeat LRR_4 PF12799.7 EAY00994.1 - 5.6e-16 58.4 18.6 1.3 9.5 0.0 13.7 3 1 11 16 16 16 7 Leucine Rich repeats (2 copies) Acetyltransf_19 PF18015.1 EAY00994.1 - 0.0094 16.2 9.5 6 7.1 0.1 6.3 1 1 7 9 9 9 1 Acetyltransferase (GNAT) domain PulA_N1 PF17999.1 EAY00994.1 - 0.02 15.6 7.2 10 7.0 0.1 5.8 4 1 4 8 8 8 0 Pullulanase N1-terminal domain Adaptin_N PF01602.20 EAY00995.1 - 1.4e-62 212.0 16.6 1.8e-62 211.6 16.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 EAY00995.1 - 0.00012 20.8 2.2 0.00025 19.7 2.2 1.5 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.7 EAY00995.1 - 0.0021 18.1 5.6 0.4 10.7 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 NADH_dhqG_C PF09326.11 EAY00996.1 - 0.11 13.2 0.1 0.27 12.0 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal LPD3 PF18798.1 EAY00997.1 - 0.093 13.0 4.4 0.12 12.6 2.2 2.1 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 Glyco_hydro_77 PF02446.17 EAY00998.1 - 4e-149 497.5 5.7 5.2e-149 497.1 5.7 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EAY00998.1 - 1.5e-42 143.4 1.4 7.6e-22 77.0 0.8 2.7 2 0 0 2 2 2 2 Starch binding domain Cullin PF00888.22 EAY01000.1 - 5.4e-62 210.3 47.0 5.4e-62 210.3 47.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EAY01000.1 - 5.8e-06 26.3 0.0 5.8e-06 26.3 0.0 4.1 4 0 0 4 4 4 1 Cullin protein neddylation domain Pan3_PK PF18101.1 EAY01000.1 - 0.0041 17.1 0.5 0.037 14.0 0.0 2.9 3 0 0 3 3 3 1 Pan3 Pseudokinase domain UQ_con PF00179.26 EAY01001.1 - 2.5e-40 137.4 0.1 2.8e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EAY01001.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Ank_2 PF12796.7 EAY01002.1 - 1.4e-43 147.4 7.3 2e-12 47.5 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01002.1 - 6.6e-40 135.0 6.6 9.1e-08 32.5 0.2 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAY01002.1 - 6.3e-34 114.9 12.1 8e-06 26.1 0.0 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAY01002.1 - 5.9e-33 112.5 7.2 4.3e-07 30.1 0.1 5.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01002.1 - 2.2e-32 107.4 10.7 2.7e-05 24.2 0.0 8.9 8 1 0 8 8 8 8 Ankyrin repeat T2SSE_N PF05157.15 EAY01002.1 - 0.02 15.2 0.1 0.067 13.5 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain FMN_red PF03358.15 EAY01003.1 - 1.6e-17 63.6 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAY01003.1 - 1.7e-11 44.2 0.0 2.4e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold P68HR PF08061.11 EAY01003.1 - 0.042 14.0 0.9 0.075 13.2 0.0 1.9 2 0 0 2 2 2 0 P68HR (NUC004) repeat Flavodoxin_5 PF12724.7 EAY01003.1 - 0.15 12.3 0.0 4 7.7 0.0 2.5 3 0 0 3 3 3 0 Flavodoxin domain WD40 PF00400.32 EAY01004.1 - 0.0081 17.0 17.3 0.11 13.4 0.2 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4394 PF14339.6 EAY01004.1 - 0.019 14.4 0.1 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) CPSF_A PF03178.15 EAY01004.1 - 0.095 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 CPSF A subunit region DUF3698 PF12479.8 EAY01004.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) 2-Hacid_dh_C PF02826.19 EAY01005.1 - 3.1e-42 143.9 0.0 5.1e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAY01005.1 - 1.4e-31 109.0 1.2 2.6e-31 108.0 1.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAY01005.1 - 2.4e-06 27.8 0.4 2.4e-06 27.8 0.4 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAY01005.1 - 0.0005 20.6 2.1 0.0042 17.6 0.1 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DDR_swiveling PF18427.1 EAY01005.1 - 0.062 13.3 0.7 0.18 11.8 0.0 2.0 3 0 0 3 3 3 0 DD-reactivating factor swiveling domain BP28CT PF08146.12 EAY01006.1 - 0.00014 21.8 12.7 0.00016 21.5 7.8 3.7 2 1 0 2 2 2 1 BP28CT (NUC211) domain CDC37_M PF08565.11 EAY01006.1 - 0.042 13.8 3.6 2.8 7.9 0.6 3.3 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain Telomere_reg-2 PF10193.9 EAY01006.1 - 1.6 9.2 8.0 26 5.3 0.1 5.8 6 0 0 6 6 6 0 Telomere length regulation protein Ank_4 PF13637.6 EAY01007.1 - 8.9e-23 80.4 0.2 2.4e-11 43.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01007.1 - 5.2e-20 70.9 0.3 3.4e-10 39.9 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAY01007.1 - 2.3e-18 66.5 1.0 7.6e-15 55.3 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01007.1 - 1.1e-15 57.5 0.8 1.5e-12 47.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01007.1 - 2.5e-14 52.0 0.1 6.7e-06 26.1 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_S6 PF01250.17 EAY01007.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein S6 PGM_PMM_I PF02878.16 EAY01007.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF3447 PF11929.8 EAY01008.1 - 5.1e-13 48.8 4.8 5.1e-13 48.8 4.8 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) MA3 PF02847.17 EAY01008.1 - 0.051 13.6 0.7 0.57 10.2 0.7 2.3 1 1 0 1 1 1 0 MA3 domain FAS_N PF17828.1 EAY01008.1 - 0.16 12.0 1.8 0.23 11.5 0.2 2.2 2 1 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta Ank_2 PF12796.7 EAY01009.1 - 1.7e-73 243.2 58.5 2.1e-18 66.7 9.1 6.9 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01009.1 - 6.3e-63 206.7 26.6 1.3e-07 31.7 0.3 9.8 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 EAY01009.1 - 3.3e-62 206.1 18.4 5.9e-09 36.3 0.4 10.5 4 1 7 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01009.1 - 1.5e-56 187.7 35.8 2.9e-12 46.6 0.3 8.2 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01009.1 - 5.3e-48 155.4 24.1 9.7e-06 25.6 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat DUF3447 PF11929.8 EAY01009.1 - 3.7e-37 126.1 4.4 3.7e-37 126.1 4.4 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) CDP-OH_P_transf PF01066.21 EAY01010.1 - 1.1e-13 51.7 1.2 1.1e-13 51.7 1.2 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Rrn6 PF10214.9 EAY01011.1 - 0.33 9.4 2.2 0.45 8.9 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S49_N PF08496.10 EAY01011.1 - 0.93 9.5 4.8 0.65 10.0 0.3 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PNISR PF15996.5 EAY01011.1 - 1.8 8.8 14.5 2.5 8.3 14.5 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BUD22 PF09073.10 EAY01011.1 - 6.8 5.9 17.5 9.5 5.4 17.5 1.1 1 0 0 1 1 1 0 BUD22 Syntaxin-6_N PF09177.11 EAY01012.1 - 0.15 12.6 23.6 0.53 10.9 3.6 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Nif11 PF07862.11 EAY01012.1 - 4.2 7.7 10.0 2.5 8.5 0.8 3.4 3 0 0 3 3 3 0 Nif11 domain Metallophos PF00149.28 EAY01014.1 - 1.6e-36 126.7 0.0 2.1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAY01014.1 - 0.0051 17.0 0.0 0.0075 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RT_RNaseH_2 PF17919.1 EAY01015.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Gp45_2 PF17470.2 EAY01015.1 - 0.066 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Phage gene product 45.2 DUF489 PF04356.12 EAY01015.1 - 0.49 10.4 2.1 0.55 10.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Laminin_I PF06008.14 EAY01017.1 - 8.6e-13 48.6 43.5 0.0095 15.7 3.5 5.7 1 1 5 6 6 6 5 Laminin Domain I DUF3552 PF12072.8 EAY01017.1 - 3.3e-11 43.0 29.6 0.06 12.8 2.2 7.4 1 1 7 8 8 8 8 Domain of unknown function (DUF3552) KASH_CCD PF14662.6 EAY01017.1 - 8.5e-10 38.8 42.7 0.0009 19.1 12.1 4.1 1 1 3 4 4 4 3 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 EAY01017.1 - 3.3e-08 33.7 25.1 0.046 13.5 2.1 4.4 1 1 3 4 4 4 4 Ezrin/radixin/moesin family Spc7 PF08317.11 EAY01017.1 - 4.1e-07 29.2 43.4 0.0085 15.0 9.2 4.5 1 1 5 6 6 6 5 Spc7 kinetochore protein DUF4686 PF15742.5 EAY01017.1 - 6.4e-05 22.3 46.5 0.013 14.7 15.7 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4686) Tropomyosin_1 PF12718.7 EAY01017.1 - 0.0006 20.0 29.2 0.091 12.9 5.8 5.3 1 1 3 5 5 5 3 Tropomyosin like BLOC1_2 PF10046.9 EAY01017.1 - 0.00061 20.0 36.7 1.8 8.9 0.7 7.8 1 1 6 7 7 7 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 EAY01017.1 - 0.00074 19.9 0.6 22 5.5 0.0 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.9 EAY01017.1 - 0.00095 19.4 48.3 1.6 9.0 8.1 5.9 1 1 5 6 6 6 2 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EAY01017.1 - 0.001 19.1 28.3 1.1 9.3 2.2 5.1 1 1 3 5 5 5 4 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EAY01017.1 - 0.0015 17.9 74.7 0.17 11.1 11.4 5.1 1 1 4 5 5 5 5 Protein of unknown function (DUF3450) ZapB PF06005.12 EAY01017.1 - 0.0024 18.3 27.3 16 6.0 0.8 7.8 1 1 5 6 6 6 0 Cell division protein ZapB YabA PF06156.13 EAY01017.1 - 0.0039 17.8 14.5 28 5.4 0.2 5.5 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EAY01017.1 - 0.0088 16.1 69.5 0.67 10.0 16.1 4.6 1 1 3 4 4 4 3 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 EAY01017.1 - 0.027 14.6 39.6 1.4 9.0 4.9 5.4 1 1 5 6 6 6 0 BRE1 E3 ubiquitin ligase Exonuc_VII_S PF02609.16 EAY01017.1 - 0.034 14.2 13.3 1.2 9.3 0.1 7.0 2 2 5 9 9 9 0 Exonuclease VII small subunit CENP-F_leu_zip PF10473.9 EAY01017.1 - 0.051 13.6 33.9 0.2 11.7 5.0 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0449 PF15136.6 EAY01017.1 - 0.052 14.0 42.6 20 5.8 3.1 7.2 1 1 2 3 3 2 0 Uncharacterised protein family UPF0449 Laminin_II PF06009.12 EAY01017.1 - 0.079 13.0 41.8 1.2 9.1 3.1 5.3 1 1 4 5 5 5 0 Laminin Domain II APG6_N PF17675.1 EAY01017.1 - 0.43 11.1 51.9 16 6.0 8.6 5.0 1 1 3 4 4 4 0 Apg6 coiled-coil region Sec34 PF04136.15 EAY01017.1 - 0.84 9.5 62.2 0.52 10.2 6.5 7.1 1 1 7 8 8 8 0 Sec34-like family PI3K_P85_iSH2 PF16454.5 EAY01017.1 - 2 8.0 30.3 7.5 6.1 1.0 6.0 1 1 3 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4795 PF16043.5 EAY01017.1 - 2.6 7.6 45.5 14 5.2 6.2 5.5 1 1 1 2 2 1 0 Domain of unknown function (DUF4795) DUF724 PF05266.14 EAY01017.1 - 5.2 6.9 31.3 4.7 7.0 4.5 4.7 1 1 5 6 6 6 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 EAY01017.1 - 8.4 6.6 35.4 2.3 8.4 5.2 4.5 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family ABC2_membrane_3 PF12698.7 EAY01018.1 - 0.0015 17.7 0.5 0.0019 17.4 0.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Orf78 PF06024.12 EAY01018.1 - 0.019 15.2 2.9 0.088 13.1 2.9 2.0 1 1 0 1 1 1 0 Orf78 (ac78) Fzo_mitofusin PF04799.13 EAY01019.1 - 0.00048 19.7 3.9 0.00048 19.7 3.9 2.6 2 1 1 3 3 3 1 fzo-like conserved region DASH_Spc19 PF08287.11 EAY01019.1 - 0.012 15.6 1.2 0.012 15.6 1.2 1.8 2 0 0 2 2 2 0 Spc19 Apolipoprotein PF01442.18 EAY01019.1 - 0.021 14.7 0.3 0.039 13.8 0.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EAY01019.1 - 0.028 14.7 1.2 0.22 11.8 1.2 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HSBP1 PF06825.12 EAY01019.1 - 0.049 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PH_14 PF17787.1 EAY01019.1 - 0.066 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 PH domain CENP-O PF09496.10 EAY01019.1 - 0.072 13.1 2.3 0.079 12.9 1.2 1.7 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component UCH PF00443.29 EAY01019.1 - 0.09 12.3 8.3 0.062 12.8 3.4 1.8 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PTR PF12789.7 EAY01019.1 - 0.11 12.6 1.1 0.26 11.4 0.3 2.1 2 0 0 2 2 2 0 Phage tail repeat like Plk4_PB2 PF18409.1 EAY01019.1 - 0.5 11.1 3.9 2 9.2 2.8 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Jnk-SapK_ap_N PF09744.9 EAY01019.1 - 0.78 10.0 8.2 0.59 10.3 4.0 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Endotoxin_N PF03945.14 EAY01019.1 - 1.2 8.8 4.6 4.1 7.0 0.5 2.8 2 1 1 3 3 3 0 delta endotoxin, N-terminal domain DUF883 PF05957.13 EAY01019.1 - 1.8 9.3 4.8 2.8 8.6 0.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PfUIS3 PF11567.8 EAY01019.1 - 2 8.8 7.0 0.62 10.5 0.9 2.8 1 1 2 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Baculo_PEP_C PF04513.12 EAY01019.1 - 2.5 8.1 7.9 3.5 7.7 4.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 EAY01020.1 - 0.00085 20.1 0.2 0.11 13.3 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Ank_2 PF12796.7 EAY01021.1 - 1.1e-98 323.9 65.6 3.4e-16 59.6 3.8 12.5 6 3 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01021.1 - 6.9e-94 307.1 50.3 3.7e-11 43.3 0.0 18.9 6 3 14 20 20 20 18 Ankyrin repeats (many copies) Ank PF00023.30 EAY01021.1 - 9.5e-81 263.0 41.5 7.9e-07 29.3 0.0 19.4 20 0 0 20 20 20 17 Ankyrin repeat Ank_3 PF13606.6 EAY01021.1 - 4e-70 223.4 60.9 1.6e-05 24.9 0.0 22.0 23 1 0 23 23 23 17 Ankyrin repeat Ank_5 PF13857.6 EAY01021.1 - 3e-69 228.2 38.3 1.4e-11 44.4 0.1 16.0 6 4 12 18 18 18 14 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01021.1 - 3.6e-31 106.9 25.9 7.6e-31 105.9 10.8 10.7 7 4 3 10 10 10 4 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAY01021.1 - 0.016 14.9 11.1 0.48 10.0 0.0 4.3 1 1 4 5 5 5 0 Coiled coil protein 84 CEP44 PF15007.6 EAY01021.1 - 0.017 15.2 3.6 3.6 7.8 0.0 5.2 5 2 1 6 6 6 0 Centrosomal spindle body, CEP44 RibD_C PF01872.17 EAY01022.1 - 5.7e-11 42.6 0.0 6.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain RibD_C PF01872.17 EAY01023.1 - 5.7e-11 42.6 0.0 6.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain C2 PF00168.30 EAY01026.1 - 9.6e-16 57.9 0.1 1.4e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF4283 PF14111.6 EAY01027.1 - 0.026 14.0 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) RICTOR_M PF14666.6 EAY01028.1 - 0.00085 19.1 5.9 0.061 13.1 0.8 4.0 2 1 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain Glyco_hydro_52 PF03512.13 EAY01029.1 - 0.17 10.8 0.0 0.41 9.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 LRR_4 PF12799.7 EAY01029.1 - 6.9 7.2 13.2 7.2 7.2 4.4 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) WD40_like PF17005.5 EAY01030.1 - 0.0049 16.2 1.1 0.01 15.2 1.1 1.5 1 0 0 1 1 1 1 WD40-like domain IBN_N PF03810.19 EAY01031.1 - 3.8e-06 26.7 4.5 0.00019 21.3 0.2 4.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EAY01031.1 - 0.00016 21.9 0.0 3.2 8.2 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats Arm PF00514.23 EAY01031.1 - 0.012 15.7 0.6 47 4.2 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat KRAP_IP3R_bind PF14722.6 EAY01031.1 - 0.021 14.5 0.0 0.13 12.0 0.0 2.3 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain CLASP_N PF12348.8 EAY01031.1 - 0.029 14.0 0.2 0.29 10.6 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 EAY01031.1 - 0.17 12.5 6.3 1.7 9.3 0.2 4.7 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Lipase3_N PF03893.16 EAY01032.1 - 0.1 12.6 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Lipase 3 N-terminal region F5_F8_type_C PF00754.25 EAY01033.1 - 0.00015 21.9 0.9 0.00061 19.9 0.4 2.2 2 0 0 2 2 2 1 F5/8 type C domain RRM_1 PF00076.22 EAY01033.1 - 0.011 15.5 0.5 0.12 12.2 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GyrI-like PF06445.15 EAY01033.1 - 0.024 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 GyrI-like small molecule binding domain Ank_4 PF13637.6 EAY01034.1 - 1.7e-09 38.0 0.0 8.9e-05 23.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01034.1 - 2.3e-08 34.1 0.2 2e-06 28.0 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01034.1 - 7.1e-07 29.7 0.2 1.5e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01034.1 - 7.2e-07 29.4 0.5 0.37 11.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAY01034.1 - 5.7e-06 26.3 0.4 0.46 11.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAY01035.1 - 6.8e-37 125.3 5.7 6.8e-37 125.3 5.7 4.8 5 1 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01035.1 - 7.3e-32 109.8 9.5 9.7e-12 45.3 1.5 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01035.1 - 4.2e-31 106.9 4.2 3.5e-10 40.2 0.1 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01035.1 - 4.7e-26 90.0 2.9 4.6e-07 30.0 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAY01035.1 - 8.8e-24 81.0 8.4 8.6e-05 22.7 0.0 7.7 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAY01035.1 - 1.7e-18 66.4 2.0 4.5e-08 33.2 0.0 4.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) ApbE PF02424.15 EAY01035.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 ApbE family Phage_TTP_13 PF16463.5 EAY01035.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein family KIF1B PF12423.8 EAY01036.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinesin protein 1B KIF1B PF12423.8 EAY01037.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinesin protein 1B Spc7 PF08317.11 EAY01038.1 - 0.00099 18.1 20.1 0.00099 18.1 20.1 9.5 4 3 5 9 9 9 5 Spc7 kinetochore protein LRR_5 PF13306.6 EAY01039.1 - 9.9e-114 374.7 72.1 1.8e-27 95.8 13.3 6.1 2 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01039.1 - 6.6e-23 80.2 15.7 0.00087 19.0 0.0 8.6 5 2 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 EAY01039.1 - 0.08 13.4 26.7 1.7 9.2 1.2 8.0 8 1 1 9 9 9 0 Leucine Rich repeats (2 copies) NosD PF05048.13 EAY01039.1 - 9.5 5.4 10.4 2.9 7.1 7.4 1.7 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Peptidase_M8 PF01457.16 EAY01040.1 - 2.9e-32 112.1 0.2 4.1e-32 111.6 0.2 1.2 1 0 0 1 1 1 1 Leishmanolysin DUF4834 PF16118.5 EAY01040.1 - 0.0001 23.2 1.9 0.0001 23.2 1.9 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) Connexin PF00029.19 EAY01040.1 - 0.00017 21.5 0.2 0.00025 20.9 0.2 1.3 1 0 0 1 1 1 1 Connexin FAM176 PF14851.6 EAY01040.1 - 0.00053 19.7 0.6 0.0012 18.6 0.6 1.6 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 EAY01040.1 - 0.00085 20.2 0.2 0.003 18.4 0.2 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 EAY01040.1 - 0.00098 19.2 4.8 0.0021 18.1 4.8 1.5 1 0 0 1 1 1 1 Protocadherin Shisa PF13908.6 EAY01040.1 - 0.0018 18.5 0.1 0.0036 17.6 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.11 EAY01040.1 - 0.003 17.3 0.3 0.0075 16.0 0.3 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein SID-1_RNA_chan PF13965.6 EAY01040.1 - 0.0051 15.3 0.5 0.0073 14.8 0.5 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 LRR19-TM PF15176.6 EAY01040.1 - 0.0063 16.5 0.3 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain V_ATPase_I PF01496.19 EAY01040.1 - 0.0069 14.4 1.5 0.0095 13.9 1.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MAP17 PF15807.5 EAY01040.1 - 0.012 15.8 3.8 0.027 14.7 3.8 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Serinc PF03348.15 EAY01040.1 - 0.014 14.3 0.2 0.019 13.9 0.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) ECSCR PF15820.5 EAY01040.1 - 0.017 14.9 0.3 0.054 13.3 0.3 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Zip PF02535.22 EAY01040.1 - 0.017 14.3 0.3 0.03 13.6 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Myc_target_1 PF15179.6 EAY01040.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 DUF4446 PF14584.6 EAY01040.1 - 0.025 14.5 1.7 0.047 13.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMEM51 PF15345.6 EAY01040.1 - 0.048 13.5 0.2 0.093 12.6 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 LST1 PF05083.13 EAY01040.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 LST-1 protein Peptidase_S49_N PF08496.10 EAY01040.1 - 0.058 13.5 5.5 0.13 12.3 5.5 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3810 PF12725.7 EAY01040.1 - 0.059 12.7 0.7 5.9 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TMIE PF16038.5 EAY01040.1 - 0.067 13.0 2.6 0.13 12.1 2.6 1.4 1 0 0 1 1 1 0 TMIE protein RCR PF12273.8 EAY01040.1 - 0.088 13.5 0.0 4.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TRAP_alpha PF03896.16 EAY01040.1 - 0.099 11.8 0.5 0.15 11.3 0.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit O-antigen_lig PF13425.6 EAY01040.1 - 0.13 11.1 3.3 0.18 10.5 3.3 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 EAY01040.1 - 0.13 12.3 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.18 EAY01040.1 - 0.16 11.3 0.3 0.27 10.6 0.3 1.3 1 0 0 1 1 1 0 Nucleoside transporter DUF1180 PF06679.12 EAY01040.1 - 0.17 12.3 0.1 0.34 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CYYR1 PF10873.8 EAY01040.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.2 2 0 0 2 2 1 0 Cysteine and tyrosine-rich protein 1 DAP10 PF07213.11 EAY01040.1 - 0.65 10.0 3.3 0.24 11.4 0.4 1.7 2 0 0 2 2 1 0 DAP10 membrane protein Coilin_N PF15862.5 EAY01040.1 - 0.88 9.4 14.4 1.7 8.4 14.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus TMEM154 PF15102.6 EAY01040.1 - 2.3 8.1 9.8 0.25 11.3 4.5 1.8 1 1 1 2 2 2 0 TMEM154 protein family Metallophos PF00149.28 EAY01041.1 - 2.7e-32 112.9 0.0 3.6e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HAP1_N PF04849.13 EAY01042.1 - 0.00024 20.4 14.9 0.00024 20.4 14.9 2.1 1 1 1 2 2 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.21 EAY01042.1 - 0.0018 18.3 2.2 0.0018 18.3 2.2 4.9 4 1 0 5 5 5 1 bZIP transcription factor DivIC PF04977.15 EAY01042.1 - 0.0058 16.4 2.1 0.0058 16.4 2.1 3.9 3 2 1 5 5 5 2 Septum formation initiator TSC22 PF01166.18 EAY01042.1 - 0.0098 16.2 1.1 0.0098 16.2 1.1 3.5 3 0 0 3 3 3 1 TSC-22/dip/bun family FCH PF00611.23 EAY01042.1 - 0.031 14.6 2.6 0.035 14.4 1.0 2.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain bZIP_2 PF07716.15 EAY01042.1 - 0.076 13.1 1.2 0.076 13.1 1.2 3.9 4 0 0 4 4 4 0 Basic region leucine zipper HALZ PF02183.18 EAY01042.1 - 0.1 12.8 0.6 0.1 12.8 0.6 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Csm1_N PF18504.1 EAY01042.1 - 0.96 9.8 22.2 2.1 8.8 3.7 4.3 3 1 1 4 4 4 0 Csm1 N-terminal domain Glutaredoxin2_C PF04399.13 EAY01042.1 - 1.5 8.7 11.4 0.15 11.9 1.5 3.0 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain Herpes_BLRF2 PF05812.12 EAY01042.1 - 1.6 8.9 10.2 0.64 10.2 1.2 2.8 2 1 0 3 3 3 0 Herpesvirus BLRF2 protein YtxH PF12732.7 EAY01042.1 - 3.5 8.2 9.9 9.2 6.9 0.6 3.2 3 1 0 3 3 3 0 YtxH-like protein DUF1192 PF06698.11 EAY01042.1 - 6.7 6.9 8.4 1.9 8.6 1.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) UQ_con PF00179.26 EAY01043.1 - 2.3e-11 43.5 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF5010_C PF18099.1 EAY01043.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 2 0 0 2 2 2 0 DUF5010 C-terminal domain BACK PF07707.15 EAY01044.1 - 0.0019 18.3 1.1 0.0032 17.5 1.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch PSP PF04046.16 EAY01045.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY01046.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat MeaB PF03308.16 EAY01048.1 - 0.052 12.5 0.8 0.072 12.1 0.5 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_D5 PF03288.16 EAY01049.1 - 3.9e-05 24.1 2.1 0.00017 22.0 2.1 2.2 1 1 0 1 1 1 1 Poxvirus D5 protein-like Pkinase_Tyr PF07714.17 EAY01050.1 - 5.1e-53 180.0 0.0 7.9e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAY01050.1 - 2.8e-50 171.2 0.0 1.3e-49 169.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EAY01050.1 - 3.5e-06 26.6 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Csm1_B PF18211.1 EAY01050.1 - 0.036 13.9 0.2 0.083 12.7 0.2 1.6 1 0 0 1 1 1 0 Csm1 subunit domain B Kdo PF06293.14 EAY01050.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAY01050.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EAY01050.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EAY01050.1 - 0.28 11.1 0.0 0.45 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GPS2_interact PF15784.5 EAY01051.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01051.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Alkyl_sulf_C PF14864.6 EAY01053.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DUF5398 PF17376.2 EAY01054.1 - 0.071 13.7 0.2 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5398) SPO22 PF08631.10 EAY01054.1 - 0.15 11.5 10.6 0.4 10.1 0.0 4.3 5 1 1 6 6 6 0 Meiosis protein SPO22/ZIP4 like Transpeptidase PF00905.22 EAY01054.1 - 0.21 10.8 0.1 0.72 9.0 0.0 1.8 2 0 0 2 2 2 0 Penicillin binding protein transpeptidase domain Vac14_Fab1_bd PF12755.7 EAY01054.1 - 0.26 11.9 1.7 4.9 7.8 0.2 3.9 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 EAY01054.1 - 6.7 6.5 11.3 0.45 10.3 0.2 4.1 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) V-SNARE_C PF12352.8 EAY01055.1 - 0.1 12.9 0.4 0.35 11.2 0.2 1.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 EAY01055.1 - 1.9 8.6 6.2 0.27 11.2 2.0 1.8 3 0 0 3 3 3 0 SNARE domain Ribonuclease_3 PF00636.26 EAY01056.1 - 2.2e-23 82.9 0.1 9.9e-12 45.4 0.1 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EAY01056.1 - 1.1e-22 80.6 0.0 6.9e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like Ank_2 PF12796.7 EAY01058.1 - 7.1e-67 222.0 45.2 6.1e-20 71.6 3.4 6.7 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01058.1 - 9.7e-53 175.9 23.7 1.5e-10 41.3 0.1 9.8 4 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 EAY01058.1 - 4.9e-47 156.4 24.6 4.3e-07 30.1 0.0 10.7 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 EAY01058.1 - 1.5e-45 147.9 22.4 8.8e-05 22.6 0.0 11.9 11 1 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 EAY01058.1 - 2e-41 139.5 12.8 3.9e-09 36.6 0.4 9.0 3 3 8 11 11 11 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01058.1 - 1.4e-23 82.6 6.7 1.4e-23 82.6 6.7 7.9 3 2 6 9 9 9 4 Domain of unknown function (DUF3447) Sacchrp_dh_NADP PF03435.18 EAY01058.1 - 0.047 14.0 0.9 33 4.8 0.1 3.6 1 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 EAY01059.1 - 8.2e-48 160.9 32.9 9.8e-18 64.5 5.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01059.1 - 3.1e-47 158.3 14.3 4.1e-11 43.2 1.3 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAY01059.1 - 4.2e-42 140.8 26.3 4.8e-07 29.9 0.1 7.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAY01059.1 - 4.2e-34 112.7 12.0 6e-05 23.1 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAY01059.1 - 6e-31 106.1 26.0 3.4e-10 40.0 0.9 5.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) SyrA PF11089.8 EAY01059.1 - 0.28 11.3 0.7 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Exopolysaccharide production repressor MCC-bdg_PDZ PF10506.9 EAY01059.1 - 0.52 10.4 9.7 16 5.6 0.0 4.9 6 0 0 6 6 6 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Myb_DNA-binding PF00249.31 EAY01060.1 - 2.1e-29 101.4 0.6 2.3e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01060.1 - 4.5e-21 74.9 3.9 3.3e-14 52.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY01060.1 - 9.2e-07 28.7 0.7 0.00086 19.2 0.4 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAY01060.1 - 1.7e-05 24.8 0.5 0.0048 16.9 0.0 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EAY01060.1 - 0.027 14.7 0.0 0.29 11.3 0.0 2.5 1 1 1 2 2 2 0 Rap1 Myb domain MULE PF10551.9 EAY01061.1 - 2e-10 41.0 2.2 7.6e-10 39.1 1.5 2.3 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAY01061.1 - 0.002 18.2 1.1 0.0088 16.1 1.1 2.1 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAY01061.1 - 0.007 15.3 0.2 0.012 14.5 0.2 1.3 1 0 0 1 1 1 1 Transposase, Mutator family WRKY PF03106.15 EAY01061.1 - 0.12 12.6 2.2 0.15 12.3 0.2 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain DUF21 PF01595.20 EAY01062.1 - 0.01 15.6 0.7 0.01 15.6 0.7 1.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Baculo_PEP_C PF04513.12 EAY01063.1 - 2.6e-06 27.5 34.5 0.049 13.7 1.7 5.2 1 1 4 5 5 5 5 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EAY01063.1 - 0.021 14.9 38.7 0.83 9.7 2.6 6.5 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) ApoO PF09769.9 EAY01063.1 - 0.14 12.1 18.2 3.3 7.7 0.2 4.8 4 1 0 4 4 4 0 Apolipoprotein O DUF3447 PF11929.8 EAY01064.1 - 3.8e-33 113.3 3.8 3.8e-33 113.3 3.8 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01064.1 - 1.4e-12 48.0 0.1 2.2e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01064.1 - 2.4e-09 37.6 0.5 5.8e-07 29.9 0.0 4.0 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01064.1 - 8.5e-08 31.9 2.6 1.7e-06 27.9 0.0 4.0 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 EAY01064.1 - 4.7e-07 30.0 0.0 8.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAY01064.1 - 0.0013 19.0 0.0 0.0096 16.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_C14 PF00656.22 EAY01066.1 - 0.0064 16.5 0.4 0.01 15.8 0.4 1.5 1 1 0 1 1 1 1 Caspase domain AMP-binding PF00501.28 EAY01067.1 - 7.8e-81 271.8 0.0 9.9e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SLATT_5 PF18160.1 EAY01068.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TPR_MLP1_2 PF07926.12 EAY01069.1 - 0.043 13.9 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY01069.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY01069.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Sec6 PF06046.13 EAY01070.1 - 0.0034 15.8 0.1 0.0048 15.3 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Endonuclease_7 PF02945.15 EAY01070.1 - 0.02 14.8 1.4 0.069 13.1 0.1 2.2 2 0 0 2 2 2 0 Recombination endonuclease VII zf-C2H2_4 PF13894.6 EAY01070.1 - 0.039 14.8 13.1 5 8.2 2.9 3.9 4 0 0 4 4 3 0 C2H2-type zinc finger zf-RVT PF13966.6 EAY01070.1 - 0.043 14.5 4.1 0.71 10.6 0.3 3.1 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase zf-C2H2_jaz PF12171.8 EAY01070.1 - 0.07 13.4 7.9 1.6 9.1 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAY01070.1 - 0.1 13.0 10.9 2.5 8.6 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAY01070.1 - 0.15 12.4 11.2 27 5.2 2.0 3.6 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) OTT_1508_deam PF14441.6 EAY01070.1 - 0.23 11.5 7.1 0.14 12.2 0.6 2.5 2 0 0 2 2 2 0 OTT_1508-like deaminase zf-Di19 PF05605.12 EAY01070.1 - 0.41 11.0 11.1 1.9 8.8 0.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EAY01070.1 - 0.69 10.5 5.7 40 4.9 0.2 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 EAY01070.1 - 0.83 9.3 7.0 2.1 8.0 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 EAY01070.1 - 3.1 6.2 11.4 0.62 8.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Zn-ribbon_8 PF09723.10 EAY01070.1 - 4.4 7.5 5.8 31 4.8 0.6 3.2 3 0 0 3 3 3 0 Zinc ribbon domain RUN PF02759.19 EAY01071.1 - 0.075 13.0 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 RUN domain DUF282 PF03380.14 EAY01073.1 - 0.00017 21.5 0.5 0.00022 21.1 0.5 1.3 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF282 HTH_48 PF17906.1 EAY01073.1 - 0.0033 17.5 0.1 0.0038 17.3 0.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Pep1_7 PF17232.2 EAY01073.1 - 0.011 16.1 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 0 Elicitor peptide 1-7 Hid1 PF12722.7 EAY01075.1 - 4.4 5.3 17.2 5.1 5.1 17.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_IE2_3 PF03361.14 EAY01078.1 - 0.025 14.4 1.0 0.63 9.9 0.2 2.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 HEAT PF02985.22 EAY01078.1 - 0.25 11.7 1.8 6.7 7.3 0.0 3.9 5 0 0 5 5 5 0 HEAT repeat PPP5 PF08321.12 EAY01078.1 - 0.52 10.6 8.2 2.3 8.6 0.9 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region MULE PF10551.9 EAY01079.1 - 4.4e-10 39.9 0.2 6.9e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EAY01079.1 - 0.044 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EAY01079.1 - 0.094 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DUF1196 PF06709.11 EAY01079.1 - 0.38 10.9 2.4 1.5 9.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1196) DUF4168 PF13767.6 EAY01081.1 - 0.51 11.5 4.7 0.52 11.5 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) AhpC-TSA PF00578.21 EAY01083.1 - 4.2e-38 130.1 0.0 5.9e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAY01083.1 - 4.4e-16 58.9 0.0 5.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAY01083.1 - 2.7e-11 43.1 0.1 4.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_4 PF12799.7 EAY01084.1 - 9.6e-18 64.0 24.5 2.3e-07 31.0 4.1 4.4 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY01084.1 - 7.9e-13 48.3 3.3 2.1e-08 33.9 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAY01084.1 - 2e-08 33.8 19.5 0.00039 20.1 8.6 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EAY01084.1 - 0.31 11.8 24.1 28 5.8 0.1 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EAY01084.1 - 0.69 10.1 19.6 2.1 8.6 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Cytochrome_C554 PF13435.6 EAY01085.1 - 0.026 15.4 1.3 0.72 10.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Microtub_bind PF13931.6 EAY01085.1 - 0.032 14.6 1.3 0.04 14.3 1.3 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Yippee-Mis18 PF03226.14 EAY01085.1 - 0.043 14.0 0.3 0.14 12.4 0.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TRAF6_Z2 PF18048.1 EAY01085.1 - 0.21 11.7 3.7 4.9 7.3 0.2 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF4138 PF13595.6 EAY01086.1 - 0.00043 19.6 2.0 0.00053 19.3 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4138) ApoLp-III PF07464.11 EAY01086.1 - 0.016 15.3 8.3 0.053 13.6 8.0 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GLTSCR1 PF15249.6 EAY01086.1 - 0.037 14.5 2.2 0.061 13.8 2.2 1.4 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein Topoisom_I_N PF02919.15 EAY01086.1 - 0.044 13.3 4.5 0.036 13.6 3.5 1.3 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment eIF3_subunit PF08597.10 EAY01088.1 - 1.5e-07 31.6 3.7 1.6e-07 31.5 3.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF1104 PF06518.11 EAY01088.1 - 0.0021 18.4 2.6 0.0029 17.9 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) DnaI_N PF07319.11 EAY01088.1 - 0.0094 16.6 2.7 0.012 16.3 2.7 1.1 1 0 0 1 1 1 1 Primosomal protein DnaI N-terminus MIEAP PF16026.5 EAY01088.1 - 0.011 15.9 0.3 0.015 15.6 0.3 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein T4_Rnl2_C PF18043.1 EAY01088.1 - 0.039 14.1 0.4 0.058 13.5 0.4 1.4 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal FKBP_N PF01346.18 EAY01088.1 - 0.059 14.3 3.4 0.073 14.0 3.4 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF5071 PF16804.5 EAY01088.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Ank_2 PF12796.7 EAY01089.1 - 1.7e-44 150.3 23.9 8.5e-17 61.5 3.9 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01089.1 - 2.9e-44 148.9 8.3 1.4e-13 51.0 0.2 8.0 4 1 4 8 8 8 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01089.1 - 3e-41 139.2 4.0 3e-41 139.2 4.0 4.3 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAY01089.1 - 8.6e-41 136.6 8.7 5.5e-07 29.8 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAY01089.1 - 1.3e-32 108.2 14.2 6.1e-05 23.1 0.0 8.9 9 1 1 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EAY01089.1 - 2.9e-23 81.6 4.0 1.4e-08 34.8 0.2 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) M16C_assoc PF08367.11 EAY01090.1 - 1.6e-47 161.8 1.6 1.6e-47 161.8 1.6 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAY01090.1 - 3.6e-19 69.5 0.7 1.4e-14 54.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAY01090.1 - 2.8e-11 43.6 3.0 4.1e-10 39.8 0.1 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) RPM2 PF08579.11 EAY01090.1 - 0.26 11.7 3.0 5.9 7.3 0.2 3.8 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) EF-hand_12 PF17901.1 EAY01090.1 - 0.3 11.6 2.2 19 5.8 0.0 3.4 3 0 0 3 3 3 0 EF-hand fold domain DUF2808 PF10989.8 EAY01091.1 - 0.0037 17.3 0.2 0.29 11.1 0.2 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2808) DUF3781 PF12636.7 EAY01092.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAY01093.1 - 7.3e-73 244.1 3.0 9.5e-73 243.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Peptidase_M8 PF01457.16 EAY01095.1 - 5.4e-08 32.0 0.3 5.7e-08 31.9 0.3 1.2 1 0 0 1 1 1 1 Leishmanolysin ROK PF00480.20 EAY01096.1 - 1.3e-50 172.6 0.3 1.7e-50 172.2 0.3 1.1 1 0 0 1 1 1 1 ROK family Dioxygenase_N PF04444.14 EAY01100.1 - 0.012 15.4 1.0 0.14 12.0 0.0 2.3 1 1 0 2 2 2 0 Catechol dioxygenase N terminus LRR_5 PF13306.6 EAY01101.1 - 6.2e-100 330.1 108.1 4.2e-32 110.8 18.1 5.3 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01101.1 - 9.8e-39 130.9 45.6 2e-08 33.9 1.8 10.7 5 5 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 EAY01101.1 - 1.6e-05 25.1 57.1 0.068 13.6 1.0 10.2 4 3 7 12 12 12 8 Leucine Rich repeats (2 copies) SLT_beta PF02258.16 EAY01101.1 - 2.5 8.2 16.1 11 6.1 0.0 7.8 7 4 5 12 12 12 0 Shiga-like toxin beta subunit Ank_2 PF12796.7 EAY01102.1 - 2.6e-76 252.3 56.7 4.3e-19 68.9 6.2 7.3 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01102.1 - 2.6e-71 235.1 31.9 6.4e-13 48.9 0.1 11.6 4 1 9 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 EAY01102.1 - 3.6e-64 210.6 34.0 1.2e-08 35.1 0.1 10.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 EAY01102.1 - 3.3e-58 186.8 30.5 2.1e-07 30.7 0.1 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EAY01102.1 - 5.9e-44 147.5 21.9 2.8e-10 40.2 0.2 8.4 5 4 4 10 10 10 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01102.1 - 5.9e-38 128.7 8.6 5.9e-38 128.7 8.6 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) MetallophosN PF16371.5 EAY01102.1 - 4.8e-06 26.8 0.0 1.7 8.9 0.0 5.5 3 1 2 5 5 5 1 N terminal of Calcineurin-like phosphoesterase PrmC_N PF17827.1 EAY01102.1 - 0.037 14.6 1.3 37 5.0 0.1 5.1 1 1 5 6 6 6 0 PrmC N-terminal domain ATP13 PF12921.7 EAY01102.1 - 0.08 12.8 0.7 0.38 10.6 0.7 2.2 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF3718 PF12514.8 EAY01102.1 - 1.1 9.4 18.9 27 5.0 0.2 8.0 6 2 2 8 8 8 0 Protein of unknown function (DUF3718) Steroid_dh PF02544.16 EAY01103.1 - 4.9e-19 68.8 9.8 4.9e-19 68.8 9.8 2.1 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EAY01103.1 - 5.6e-06 26.0 1.9 8.7e-06 25.4 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EAY01103.1 - 0.0086 16.5 1.8 0.033 14.6 1.4 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Bromodomain PF00439.25 EAY01104.1 - 5e-21 74.6 0.5 9.1e-21 73.7 0.2 1.6 2 0 0 2 2 2 1 Bromodomain DUF357 PF04010.13 EAY01104.1 - 0.0057 16.7 0.4 1.8 8.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF357) zf-Sec23_Sec24 PF04810.15 EAY01105.1 - 1.6e-11 44.0 4.5 3.2e-11 43.1 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 EAY01105.1 - 2.1e-06 27.5 0.4 6.2e-06 26.0 0.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EAY01105.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 EAY01105.1 - 0.59 9.9 3.8 1.1 9.0 3.8 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Helicase_C_2 PF13307.6 EAY01107.1 - 3e-25 89.3 0.0 7.2e-25 88.1 0.0 1.6 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAY01107.1 - 8.7e-20 71.1 1.8 1.7e-19 70.1 1.8 1.5 1 0 0 1 1 1 1 DEAD_2 TPR_MLP1_2 PF07926.12 EAY01108.1 - 0.037 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY01108.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY01108.1 - 0.46 10.4 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family Gly-zipper_Omp PF13488.6 EAY01109.1 - 0.024 14.6 10.4 0.035 14.1 10.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAY01109.1 - 0.5 10.7 5.5 0.87 9.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF4625 PF15418.6 EAY01110.1 - 1e-15 58.1 27.2 8e-05 22.9 1.5 9.1 5 3 3 8 8 8 6 Domain of unknown function (DUF4625) Cadherin PF00028.17 EAY01110.1 - 2.4e-08 34.3 18.0 0.00022 21.6 0.2 8.6 6 2 2 9 9 9 1 Cadherin domain MG2 PF01835.19 EAY01110.1 - 5.6e-08 33.1 3.5 0.38 11.3 0.1 6.6 8 1 0 8 8 7 2 MG2 domain DUF2207 PF09972.9 EAY01110.1 - 2.4e-05 23.3 2.3 4.4e-05 22.4 0.1 2.4 2 1 0 2 2 2 1 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 EAY01110.1 - 8.8e-05 22.0 1.6 0.00024 20.6 1.6 1.7 1 0 0 1 1 1 1 Baculovirus 11 kDa family TMEM154 PF15102.6 EAY01110.1 - 0.002 18.0 1.5 0.007 16.3 1.5 1.9 1 0 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 EAY01110.1 - 0.0059 16.1 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Big_6 PF17936.1 EAY01110.1 - 0.0066 16.7 15.3 1.2 9.4 0.0 6.3 6 0 0 6 6 6 2 Bacterial Ig domain Big_7 PF17957.1 EAY01110.1 - 0.012 16.3 3.3 0.012 16.3 3.3 7.4 7 1 1 8 8 8 0 Bacterial Ig domain Tmemb_9 PF05434.11 EAY01110.1 - 0.014 15.3 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 TMEM9 VIT PF08487.10 EAY01110.1 - 0.043 14.0 1.1 1.9 8.7 0.1 3.1 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Arrestin_C PF02752.22 EAY01110.1 - 0.35 11.3 5.8 3.9 7.9 1.4 4.4 2 2 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF4384 PF14326.6 EAY01110.1 - 0.62 10.2 2.7 26 5.0 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4384) TQ PF18202.1 EAY01110.1 - 8.4 6.9 11.6 0.81 10.2 1.1 4.3 4 1 1 5 5 5 0 T-Q ester bond containing domain COPIIcoated_ERV PF07970.12 EAY01112.1 - 3.5e-52 177.4 0.0 4.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAY01112.1 - 5.1e-20 71.6 0.0 1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ras PF00071.22 EAY01113.1 - 6.8e-31 107.1 0.5 8.6e-31 106.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01113.1 - 5.6e-27 94.4 0.3 8.9e-27 93.7 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01113.1 - 8.7e-12 44.8 0.1 1.1e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY01113.1 - 5.8e-08 32.8 0.1 8.3e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAY01113.1 - 6.3e-07 29.4 1.0 0.0012 18.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EAY01113.1 - 1.1e-05 25.2 1.0 0.00014 21.6 1.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAY01113.1 - 2.1e-05 24.0 0.4 3e-05 23.5 0.4 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAY01113.1 - 2.7e-05 23.6 0.1 4.5e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 EAY01113.1 - 6.1e-05 22.4 1.0 0.0016 17.8 0.1 2.1 2 0 0 2 2 2 1 Septin DLIC PF05783.11 EAY01113.1 - 0.00036 19.5 0.1 0.00069 18.6 0.1 1.4 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 EAY01113.1 - 0.0006 20.4 1.4 0.00091 19.8 1.4 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAY01113.1 - 0.00072 19.5 0.0 0.066 13.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 EAY01113.1 - 0.00072 19.1 0.5 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAY01113.1 - 0.00081 19.8 0.0 0.0014 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAY01113.1 - 0.00086 18.9 1.2 0.0094 15.5 1.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EAY01113.1 - 0.0018 18.8 1.6 0.0026 18.3 1.6 1.6 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 EAY01113.1 - 0.0023 17.7 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 EAY01113.1 - 0.0027 17.7 1.3 0.018 15.0 1.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EAY01113.1 - 0.0031 17.2 0.1 0.0071 16.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EAY01113.1 - 0.0037 17.7 0.3 0.0099 16.3 0.3 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EAY01113.1 - 0.0051 16.7 0.6 0.032 14.0 0.2 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EAY01113.1 - 0.0071 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EAY01113.1 - 0.0087 16.6 0.3 0.019 15.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAY01113.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAY01113.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 EAY01113.1 - 0.03 13.5 0.9 0.056 12.6 0.8 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EAY01113.1 - 0.032 14.0 1.0 0.05 13.3 0.2 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAY01113.1 - 0.033 14.5 0.2 0.057 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAY01113.1 - 0.034 13.9 1.3 1.8 8.3 0.3 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EAY01113.1 - 0.042 13.0 3.3 0.092 11.9 0.3 2.2 1 1 0 2 2 2 0 G-protein alpha subunit VirE PF05272.11 EAY01113.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E NTPase_1 PF03266.15 EAY01113.1 - 0.059 13.3 0.5 0.12 12.3 0.3 1.6 1 1 0 1 1 1 0 NTPase MCM PF00493.23 EAY01113.1 - 0.067 12.3 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_28 PF13521.6 EAY01113.1 - 0.077 13.2 0.4 0.14 12.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAY01113.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 EAY01113.1 - 0.13 11.9 0.7 0.35 10.5 0.2 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EAY01113.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.7 EAY01114.1 - 7.3e-14 51.7 19.3 2.8e-05 24.4 0.2 5.1 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAY01114.1 - 7.7e-11 41.6 20.6 2.6e-05 23.9 3.9 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 EAY01114.1 - 2.8e-07 30.1 10.1 3 8.8 0.1 7.4 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 EAY01114.1 - 0.0018 18.1 15.9 1.5 9.1 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich repeat Ras PF00071.22 EAY01115.1 - 8.4e-46 155.5 0.1 9.7e-46 155.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01115.1 - 8.2e-31 106.7 0.1 1.8e-30 105.6 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01115.1 - 1e-14 54.4 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY01115.1 - 5e-06 26.6 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAY01115.1 - 0.00044 19.7 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAY01115.1 - 0.0005 19.7 0.1 0.04 13.4 0.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAY01115.1 - 0.0037 16.7 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAY01115.1 - 0.0061 16.5 0.1 1.2 9.1 0.1 2.5 1 1 2 3 3 3 1 RsgA GTPase DLIC PF05783.11 EAY01115.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 EAY01115.1 - 0.081 12.7 0.0 0.27 11.0 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAY01115.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 EAY01115.1 - 0.14 11.7 0.1 0.2 11.2 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Ank_2 PF12796.7 EAY01116.1 - 3.7e-55 184.4 22.5 7.6e-16 58.5 0.9 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01116.1 - 4.8e-44 148.2 10.2 1.1e-08 35.4 0.0 7.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAY01116.1 - 1.3e-41 139.2 18.4 8.9e-08 32.3 0.0 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 EAY01116.1 - 1.5e-39 129.5 15.4 0.00019 21.6 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAY01116.1 - 4.1e-38 128.9 11.6 2.6e-11 43.5 0.1 5.8 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAY01116.1 - 0.0019 18.0 6.0 0.35 10.6 0.0 4.3 2 2 1 4 4 4 1 Shigella flexneri OspC protein TPR_8 PF13181.6 EAY01116.1 - 7.1 7.1 6.2 28 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4107 PF13389.6 EAY01117.1 - 3.5e-72 241.9 4.3 4.6e-72 241.5 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Trypan_PARP PF05887.11 EAY01120.1 - 0.075 13.0 11.1 0.12 12.4 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY01121.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01121.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Peripla_BP_2 PF01497.18 EAY01123.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein XisI PF08869.11 EAY01124.1 - 0.1 13.0 0.2 2.8 8.3 0.1 2.3 2 1 0 2 2 2 0 XisI protein Seryl_tRNA_N PF02403.22 EAY01126.1 - 0.0079 16.4 2.1 0.0079 16.4 2.1 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF883 PF05957.13 EAY01126.1 - 0.029 14.9 2.6 0.49 11.0 0.3 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) AATF-Che1 PF13339.6 EAY01126.1 - 0.033 14.9 9.6 0.46 11.2 5.1 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF745 PF05335.13 EAY01126.1 - 0.063 13.0 0.2 0.063 13.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) FAP206 PF12018.8 EAY01126.1 - 0.11 11.9 4.7 0.15 11.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function Fib_alpha PF08702.10 EAY01126.1 - 0.16 12.1 8.5 0.043 14.0 2.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1912 PF08930.10 EAY01126.1 - 0.27 11.4 2.2 8 6.7 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1912) ATP-synt_ab_C PF00306.27 EAY01126.1 - 0.38 11.1 8.8 0.11 12.9 2.3 2.3 1 1 1 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain DUF489 PF04356.12 EAY01126.1 - 0.46 10.5 2.9 0.79 9.7 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CENP-Q PF13094.6 EAY01126.1 - 2.3 8.4 6.9 2.3 8.4 0.7 3.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CK_II_beta PF01214.18 EAY01126.1 - 5 6.9 6.5 8.6 6.1 0.1 2.3 2 1 0 2 2 2 0 Casein kinase II regulatory subunit Lipoprotein_10 PF03202.13 EAY01126.1 - 8.3 6.9 10.8 0.44 11.0 0.8 3.0 1 1 3 4 4 4 0 Putative mycoplasma lipoprotein, C-terminal region Utp11 PF03998.13 EAY01127.1 - 2.3e-33 116.2 20.2 6.5e-32 111.4 20.2 2.0 1 1 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EAY01127.1 - 0.036 13.4 0.2 0.036 13.4 0.2 2.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 PaREP1 PF05942.11 EAY01127.1 - 0.052 13.5 1.4 0.073 13.0 0.2 1.9 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family DUF4810 PF16068.5 EAY01127.1 - 0.24 12.0 0.0 0.24 12.0 0.0 2.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4810) RIIa PF02197.17 EAY01128.1 - 4.7e-07 29.4 0.0 9.9e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PI3_PI4_kinase PF00454.27 EAY01129.1 - 1.3e-49 169.3 0.2 3.6e-49 167.8 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EAY01129.1 - 1.5e-15 56.7 0.0 3.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EAY01129.1 - 8e-14 51.6 1.6 1.8e-13 50.4 1.6 1.7 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EAY01129.1 - 1.1e-13 51.4 1.9 5.6e-12 45.9 0.0 4.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EAY01129.1 - 1.3e-07 32.0 2.4 2.8e-07 30.9 0.3 2.7 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EAY01129.1 - 0.048 14.0 0.1 0.69 10.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats SPOB_a PF14689.6 EAY01129.1 - 0.11 12.3 0.2 1 9.1 0.1 2.7 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Putative_G5P PF17426.2 EAY01129.1 - 0.19 11.9 0.0 0.55 10.4 0.0 1.8 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P ThiS PF02597.20 EAY01130.1 - 0.12 13.0 0.2 1.5 9.5 0.0 2.9 3 0 0 3 3 3 0 ThiS family GCIP PF13324.6 EAY01130.1 - 0.16 11.6 2.6 0.33 10.5 2.6 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ank_4 PF13637.6 EAY01131.1 - 6.9e-07 29.7 0.1 9.6e-05 22.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01131.1 - 1.2e-05 25.4 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01131.1 - 1.4e-05 25.6 0.1 3.3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01131.1 - 0.00036 20.7 0.0 0.006 17.0 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat RecX PF02631.16 EAY01131.1 - 0.016 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 RecX family Ank PF00023.30 EAY01131.1 - 0.16 12.5 0.4 0.5 10.9 0.0 2.0 3 0 0 3 3 3 0 Ankyrin repeat DUF3447 PF11929.8 EAY01132.1 - 0.36 10.8 13.3 0.4 10.7 0.3 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01133.1 - 9.1e-92 301.8 45.9 4.7e-18 65.6 2.2 10.8 2 2 10 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01133.1 - 1.7e-81 267.6 27.6 7.3e-10 39.2 0.0 15.7 5 3 11 16 16 16 13 Ankyrin repeats (many copies) Ank PF00023.30 EAY01133.1 - 2.4e-77 252.2 21.8 1.1e-06 28.8 0.2 16.2 16 1 0 16 16 16 12 Ankyrin repeat Ank_3 PF13606.6 EAY01133.1 - 1.3e-67 215.6 26.4 2e-06 27.7 0.0 16.9 18 0 0 18 18 18 13 Ankyrin repeat Ank_5 PF13857.6 EAY01133.1 - 2e-64 212.8 20.6 1.6e-11 44.2 0.1 10.3 5 1 4 10 10 10 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01133.1 - 1e-35 121.5 9.0 1e-35 121.5 9.0 8.3 7 3 2 9 9 9 2 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAY01133.1 - 0.00063 19.9 2.3 12 6.1 0.0 4.9 5 1 1 6 6 6 2 Centrosomal spindle body, CEP44 GATase_7 PF13537.6 EAY01133.1 - 0.003 17.5 0.4 8.5 6.3 0.0 5.3 5 0 0 5 5 5 1 Glutamine amidotransferase domain DUF4500 PF14937.6 EAY01133.1 - 0.28 11.2 2.1 0.83 9.7 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Ank_2 PF12796.7 EAY01134.1 - 4.7e-50 168.1 0.1 4.1e-21 75.4 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01134.1 - 2.1e-30 104.4 0.0 4.8e-08 33.1 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01134.1 - 2e-29 101.6 0.0 1.8e-09 37.9 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01134.1 - 9.3e-25 85.9 0.0 1.3e-05 25.4 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAY01134.1 - 1.3e-20 71.3 0.0 0.00054 20.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF3083 PF11281.8 EAY01134.1 - 0.028 13.8 0.1 13 5.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3083) NLRC4_HD2 PF17776.1 EAY01134.1 - 0.13 12.8 2.6 0.22 12.1 2.6 1.3 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Stn1_C PF12659.7 EAY01135.1 - 0.03 14.3 0.8 0.11 12.5 0.1 1.9 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH DUF4152 PF13680.6 EAY01135.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) Vps4_C PF09336.10 EAY01135.1 - 0.12 12.4 0.1 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Vps4 C terminal oligomerisation domain LRR_4 PF12799.7 EAY01136.1 - 2.4e-15 56.4 9.9 1e-05 25.8 2.2 5.5 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY01136.1 - 3.9e-11 42.8 6.8 2.6e-05 23.8 0.1 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 EAY01136.1 - 1e-08 34.8 9.6 6.4e-06 25.8 1.2 4.3 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 EAY01136.1 - 5.4e-06 26.1 6.8 0.15 12.2 0.2 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EAY01136.1 - 0.0076 16.6 7.5 5 8.1 0.5 5.6 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_1 PF00560.33 EAY01137.1 - 1.3e-07 31.2 14.9 1.7 9.5 0.0 9.4 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 EAY01137.1 - 5.5e-06 26.0 33.2 1.3 9.2 0.5 10.3 14 0 0 14 14 14 4 Leucine Rich repeat LRR_4 PF12799.7 EAY01137.1 - 0.016 15.6 38.9 0.049 14.1 4.3 7.2 4 2 4 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAY01137.1 - 0.32 10.8 30.9 1.6 8.6 0.9 6.7 3 3 2 5 5 5 0 Leucine rich repeat PilN PF05137.13 EAY01137.1 - 1.1 9.4 3.7 3.4 7.9 0.2 3.2 2 1 2 4 4 4 0 Fimbrial assembly protein (PilN) Cyclin_N PF00134.23 EAY01138.1 - 0.00076 19.2 0.1 0.0021 17.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain RE_HaeIII PF09556.10 EAY01138.1 - 0.037 13.1 0.6 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 HaeIII restriction endonuclease BET PF17035.5 EAY01139.1 - 8.3e-05 22.7 1.1 0.00023 21.3 1.1 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DCX PF03607.17 EAY01139.1 - 0.14 12.2 0.0 0.63 10.2 0.0 2.1 1 0 0 1 1 1 0 Doublecortin ER_lumen_recept PF00810.18 EAY01140.1 - 4.9e-43 147.5 13.3 1.1e-42 146.4 13.3 1.6 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF962 PF06127.11 EAY01140.1 - 0.074 13.1 3.6 0.13 12.3 0.4 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF962) Filament PF00038.21 EAY01141.1 - 0.00039 20.1 54.4 0.00039 20.1 54.4 4.9 1 1 1 3 3 3 1 Intermediate filament protein UPF0242 PF06785.11 EAY01141.1 - 0.0077 16.4 21.7 0.0077 16.4 21.7 8.2 1 1 7 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus DUF3447 PF11929.8 EAY01142.1 - 1.1e-09 38.1 2.4 1.1e-09 38.1 2.4 3.9 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Pox_int_trans PF05718.12 EAY01142.1 - 0.0023 16.7 2.0 0.0033 16.2 2.0 1.2 1 0 0 1 1 1 1 Poxvirus intermediate transcription factor DUF1870 PF08965.10 EAY01142.1 - 0.0053 16.8 0.7 0.009 16.0 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1870) Peptidase_M14 PF00246.24 EAY01143.1 - 1.8e-16 60.8 0.3 2.2e-15 57.3 0.0 2.4 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EAY01143.1 - 7.3e-10 39.2 0.1 1.7e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Imm57 PF15596.6 EAY01143.1 - 0.042 14.2 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 57 EppA_BapA PF07268.11 EAY01144.1 - 0.0067 16.4 0.6 0.011 15.7 0.5 1.7 1 1 0 1 1 1 1 Exported protein precursor (EppA/BapA) Amidase02_C PF12123.8 EAY01145.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_B_2 PF03175.13 EAY01146.1 - 7.3e-29 100.9 7.5 1.2e-28 100.2 7.5 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral GPS2_interact PF15784.5 EAY01148.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01148.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KilA-N PF04383.13 EAY01149.1 - 5.5e-07 29.4 0.1 8.9e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 KilA-N domain DUF3839 PF12943.7 EAY01150.1 - 1.2e-145 483.3 10.3 1.5e-145 482.9 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAY01151.1 - 2.1e-30 106.0 11.1 1e-29 103.8 11.1 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Trypan_PARP PF05887.11 EAY01152.1 - 0.26 11.3 8.3 0.4 10.6 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY01153.1 - 0.028 14.9 0.5 0.035 14.6 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01153.1 - 0.11 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain T5orf172 PF10544.9 EAY01154.1 - 2e-06 28.3 0.0 4.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY01154.1 - 0.011 15.6 0.2 0.05 13.4 0.0 2.1 2 1 0 2 2 2 0 KilA-N domain Lectin_legB PF00139.19 EAY01154.1 - 0.033 13.7 0.7 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 Legume lectin domain Trypan_PARP PF05887.11 EAY01155.1 - 0.047 13.7 10.2 0.074 13.0 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNase_PH_C PF03725.15 EAY01157.1 - 0.0047 16.9 0.4 0.024 14.7 0.4 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 HemX PF04375.14 EAY01157.1 - 0.18 11.0 0.1 0.49 9.6 0.0 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tetraspanin PF00335.20 EAY01158.1 - 0.0011 18.7 0.9 0.0016 18.2 0.9 1.2 1 0 0 1 1 1 1 Tetraspanin family KilA-N PF04383.13 EAY01159.1 - 3.7e-34 116.9 0.2 5e-34 116.5 0.2 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAY01159.1 - 0.032 14.2 0.4 0.037 14.0 0.4 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAY01160.1 - 8.6e-158 523.1 13.5 1.1e-157 522.8 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAY01160.1 - 0.089 13.2 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Rx_N PF18052.1 EAY01160.1 - 0.11 12.8 1.2 2.7 8.3 0.0 3.3 3 1 0 3 3 3 0 Rx N-terminal domain NTP_transf_6 PF06042.11 EAY01160.1 - 0.2 11.5 1.3 0.67 9.8 0.5 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY01160.1 - 0.23 11.9 6.7 1.5 9.4 0.5 3.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY01160.1 - 2.2 8.6 6.1 13 6.1 0.1 3.7 4 2 2 6 6 6 0 Tup N-terminal PTR PF12789.7 EAY01162.1 - 1.6e-16 60.1 1.9 1.6e-16 60.1 1.9 5.3 5 2 0 5 5 5 1 Phage tail repeat like DUF3391 PF11871.8 EAY01162.1 - 0.017 15.7 3.9 0.17 12.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4116 PF13475.6 EAY01162.1 - 0.073 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAY01164.1 - 0.044 14.3 4.8 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY01165.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAY01166.1 - 9.8e-37 125.4 0.1 1.1e-13 51.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01166.1 - 4.3e-30 102.8 0.0 3.8e-07 30.2 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAY01166.1 - 5.3e-27 90.9 0.1 5.1e-05 23.4 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EAY01166.1 - 7.7e-27 93.3 0.0 3.8e-12 46.5 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01166.1 - 1.6e-23 82.5 0.0 1e-06 28.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 EAY01166.1 - 0.028 14.8 0.0 3.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Phage T7 capsid assembly protein baeRF_family7 PF18849.1 EAY01166.1 - 0.049 13.8 0.0 8.7 6.5 0.0 2.9 3 1 1 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 7 DUF3083 PF11281.8 EAY01166.1 - 0.089 12.1 0.0 2.6 7.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3083) EPSP_synthase PF00275.20 EAY01166.1 - 0.091 11.4 0.1 7.7 5.1 0.0 2.1 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HEAT_2 PF13646.6 EAY01167.1 - 1.1e-05 25.8 4.1 0.13 12.7 0.1 5.0 4 1 1 5 5 5 2 HEAT repeats IFRD PF05004.13 EAY01167.1 - 0.00016 20.9 13.7 1.2 8.2 0.0 5.4 3 1 2 5 5 5 3 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EAY01167.1 - 0.00041 20.4 19.2 1.8 9.0 0.1 8.1 7 0 0 7 7 7 1 HEAT repeat UME PF08064.13 EAY01167.1 - 0.00053 19.9 2.9 2.6 8.0 0.1 4.6 6 0 0 6 6 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EAY01167.1 - 0.0032 18.0 14.8 0.32 11.6 0.1 5.5 6 1 0 6 6 5 2 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EAY01167.1 - 0.0057 16.2 7.1 1.1 8.7 0.0 4.6 2 2 3 5 5 5 1 Tti2 family HEAT_EZ PF13513.6 EAY01167.1 - 0.0073 16.8 9.0 0.21 12.1 1.0 5.6 8 0 0 8 8 7 1 HEAT-like repeat Swi5 PF07061.11 EAY01167.1 - 0.029 14.4 0.0 0.2 11.7 0.0 2.5 1 0 0 1 1 1 0 Swi5 TRI12 PF06609.13 EAY01167.1 - 0.069 11.6 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) U3snoRNP10 PF12397.8 EAY01167.1 - 0.36 11.2 5.1 66 3.9 0.1 5.0 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 MOR2-PAG1_C PF14225.6 EAY01167.1 - 2.1 8.2 8.6 3.1 7.6 0.1 3.8 4 1 0 4 4 4 0 Cell morphogenesis C-terminal NUC173 PF08161.12 EAY01167.1 - 2.5 7.7 5.0 24 4.5 0.1 4.7 4 2 0 5 5 5 0 NUC173 domain DUF4042 PF13251.6 EAY01167.1 - 4.2 7.0 7.0 19 4.9 0.1 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF4042) Calreticulin PF00262.18 EAY01168.1 - 9.3e-118 393.3 13.9 1.3e-117 392.8 13.9 1.2 1 0 0 1 1 1 1 Calreticulin family SKG6 PF08693.10 EAY01169.1 - 0.00086 18.7 3.6 0.0016 17.8 3.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5385 PF17359.2 EAY01169.1 - 0.0035 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Syndecan PF01034.20 EAY01169.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EAY01169.1 - 0.017 16.0 0.8 0.069 14.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 EAY01169.1 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Podoplanin MGC-24 PF05283.11 EAY01169.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FeoB_associated PF12669.7 EAY01169.1 - 3.3 8.2 5.6 6.8 7.2 5.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Psb28 PF03912.14 EAY01170.1 - 0.0099 16.1 0.1 0.039 14.2 0.0 2.1 1 1 0 1 1 1 1 Psb28 protein DUF5385 PF17359.2 EAY01171.1 - 0.00077 19.1 0.2 0.0016 18.1 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Otopetrin PF03189.13 EAY01171.1 - 0.0028 16.5 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Otopetrin Podoplanin PF05808.11 EAY01171.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 EAY01171.1 - 0.0058 17.5 0.1 0.012 16.5 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 EAY01171.1 - 0.0084 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Insulin_TMD PF17870.1 EAY01171.1 - 0.014 15.4 4.2 0.03 14.4 4.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Herpes_gE PF02480.16 EAY01171.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orf78 PF06024.12 EAY01171.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 EAY01171.1 - 0.021 14.7 0.7 0.03 14.2 0.7 1.3 1 1 0 1 1 1 0 Rifin TMEM154 PF15102.6 EAY01171.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4366 PF14283.6 EAY01171.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Ac110_PIF PF07280.11 EAY01171.1 - 0.07 12.9 0.9 0.14 11.9 0.9 1.5 1 0 0 1 1 1 0 Per os infectivity factor AC110 Nucleoside_tran PF01733.18 EAY01171.1 - 0.074 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter FeoB_associated PF12669.7 EAY01171.1 - 0.19 12.2 2.9 0.35 11.3 2.9 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SKG6 PF08693.10 EAY01171.1 - 0.39 10.1 7.3 0.66 9.4 7.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nup192 PF11894.8 EAY01174.1 - 0.15 9.2 2.9 0.17 9.0 2.9 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 RWD PF05773.22 EAY01174.1 - 4.4 7.6 7.6 2.9 8.2 0.1 2.6 1 1 0 2 2 2 0 RWD domain HEAT_EZ PF13513.6 EAY01175.1 - 0.21 12.1 8.6 12 6.5 0.1 3.8 3 1 0 3 3 3 0 HEAT-like repeat SRTM1 PF15872.5 EAY01175.1 - 0.24 11.6 0.2 0.24 11.6 0.2 2.5 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 Fes1 PF08609.10 EAY01175.1 - 0.45 11.4 3.3 9 7.3 1.1 2.7 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 BORCS6 PF10157.9 EAY01175.1 - 0.87 9.8 5.2 6.5 7.0 1.4 2.7 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 6 SNAPc19 PF15497.6 EAY01175.1 - 2.2 8.8 5.3 1 9.9 2.5 2.0 1 1 1 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Rtt106 PF08512.12 EAY01176.1 - 0.043 14.2 5.5 1.1 9.8 0.1 4.0 4 0 0 4 4 4 0 Histone chaperone Rttp106-like DUF5385 PF17359.2 EAY01177.1 - 3.5e-05 23.5 1.1 0.00041 20.0 0.3 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5385) TMEM154 PF15102.6 EAY01177.1 - 4.3e-05 23.4 0.7 0.00036 20.5 0.1 2.4 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 EAY01177.1 - 5.3e-05 23.5 0.9 0.00012 22.4 0.1 2.0 2 0 0 2 2 1 1 Orf78 (ac78) RIFIN PF02009.16 EAY01177.1 - 0.00031 20.7 0.1 0.00031 20.7 0.1 1.6 2 0 0 2 2 2 1 Rifin DUF4448 PF14610.6 EAY01177.1 - 0.00052 19.8 2.8 0.011 15.6 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EAY01177.1 - 0.001 19.9 0.2 0.003 18.4 0.2 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 EAY01177.1 - 0.0019 18.3 0.2 0.011 15.9 0.1 2.1 2 0 0 2 2 2 1 Podoplanin DUF2207 PF09972.9 EAY01177.1 - 0.0046 15.8 0.0 0.011 14.6 0.0 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 EAY01177.1 - 0.0065 16.5 0.1 0.016 15.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) ASFV_J13L PF05568.11 EAY01177.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein ECSCR PF15820.5 EAY01177.1 - 0.0099 15.7 1.1 0.065 13.1 0.2 2.5 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator DUF3169 PF11368.8 EAY01177.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Insulin_TMD PF17870.1 EAY01177.1 - 0.043 13.9 5.8 0.093 12.8 5.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Shisa PF13908.6 EAY01177.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SIT PF15330.6 EAY01177.1 - 0.073 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Herpes_gE PF02480.16 EAY01177.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Baculo_11_kDa PF06143.11 EAY01177.1 - 0.15 11.7 1.9 0.38 10.4 1.9 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3149 PF11346.8 EAY01177.1 - 0.3 10.7 2.4 0.57 9.8 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Adeno_E3_CR2 PF02439.15 EAY01177.1 - 0.31 10.9 7.7 0.54 10.1 7.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EAY01177.1 - 1.5 8.8 5.7 3.2 7.7 5.7 1.5 1 0 0 1 1 1 0 Syndecan domain GPS2_interact PF15784.5 EAY01179.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01179.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PapD_N PF00345.20 EAY01180.1 - 0.026 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAY01181.1 - 4.1e-09 35.8 1.2 6.7e-09 35.1 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAY01181.1 - 0.059 13.4 0.0 0.57 10.2 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor gpUL132 PF11359.8 EAY01181.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Pox_A32 PF04665.12 EAY01182.1 - 3.6e-07 29.9 0.1 4.1e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Amidase02_C PF12123.8 EAY01183.1 - 0.0034 17.0 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAY01184.1 - 1e-71 240.3 4.0 1.3e-71 240.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) CLASP_N PF12348.8 EAY01185.1 - 2.7e-17 63.1 9.7 1.7e-15 57.2 4.5 2.6 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EAY01185.1 - 0.00013 21.9 2.0 0.75 10.2 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat V-ATPase_H_C PF11698.8 EAY01185.1 - 0.002 18.2 6.8 0.13 12.3 0.9 3.9 2 1 1 3 3 3 2 V-ATPase subunit H HEAT_EZ PF13513.6 EAY01185.1 - 0.0051 17.3 0.0 7.3 7.2 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 EAY01185.1 - 0.0086 16.4 0.1 7.6 7.0 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats DUF2431 PF10354.9 EAY01185.1 - 0.036 14.3 0.8 0.12 12.6 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) CHASE6_C PF17150.4 EAY01185.1 - 0.082 13.6 0.5 1.5 9.6 0.4 3.0 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Cnd1 PF12717.7 EAY01185.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.6 EAY01185.1 - 6.9 7.0 8.4 3.9 7.7 0.0 3.6 3 1 0 3 3 3 0 FANCI solenoid 2 IP_trans PF02121.18 EAY01186.1 - 4.3e-11 42.9 0.9 4.3e-11 42.9 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein BBS2_Mid PF14783.6 EAY01187.1 - 0.24 11.4 1.8 0.91 9.6 0.2 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.7 EAY01188.1 - 3.4e-18 66.0 3.9 9.1e-05 23.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01188.1 - 3e-14 53.2 4.0 6.5e-05 23.4 0.1 7.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01188.1 - 1.4e-08 34.3 13.7 0.051 14.1 0.0 8.8 9 1 1 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 EAY01188.1 - 0.00026 21.2 0.4 2.1 8.8 0.0 5.2 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY01188.1 - 0.00062 20.1 0.4 6.8 7.3 0.0 5.6 7 0 0 7 7 7 1 Ankyrin repeat DUF3447 PF11929.8 EAY01188.1 - 0.0016 18.3 2.6 0.0016 18.3 2.6 7.3 7 2 1 8 8 8 1 Domain of unknown function (DUF3447) Rsd_AlgQ PF04353.13 EAY01188.1 - 0.0049 16.8 0.8 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 EAY01188.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 TrbM Gly-zipper_Omp PF13488.6 EAY01189.1 - 0.02 14.9 10.4 0.035 14.1 10.4 1.4 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 EAY01189.1 - 0.53 10.6 5.5 0.87 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) AphA_like PF14557.6 EAY01190.1 - 0.19 11.5 0.9 1.2 8.9 0.1 2.5 2 1 1 3 3 3 0 Putative AphA-like transcriptional regulator zf-C3HC4_3 PF13920.6 EAY01192.1 - 4e-11 42.6 8.3 7.6e-11 41.7 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAY01192.1 - 2.6e-09 37.3 11.2 6.6e-09 36.0 11.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAY01192.1 - 7.5e-08 32.1 11.3 7.5e-08 32.1 11.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAY01192.1 - 4e-07 29.8 11.1 1.1e-06 28.4 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAY01192.1 - 5.8e-06 26.1 8.4 1e-05 25.3 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EAY01192.1 - 8.8e-06 25.8 4.5 1.5e-05 25.1 2.9 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EAY01192.1 - 5.1e-05 23.5 6.7 0.00014 22.1 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAY01192.1 - 5.6e-05 23.0 7.9 0.00014 21.8 7.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAY01192.1 - 7.2e-05 22.9 12.8 0.0024 18.0 10.0 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAY01192.1 - 0.0012 18.8 6.2 0.0012 18.8 6.2 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAY01192.1 - 0.0074 16.3 1.0 0.017 15.2 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 EAY01192.1 - 0.011 15.9 1.6 0.018 15.2 1.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_6 PF14835.6 EAY01192.1 - 0.013 15.3 3.4 0.013 15.3 3.4 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FixQ PF05545.11 EAY01192.1 - 0.54 10.3 3.6 0.23 11.4 0.6 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Malic_M PF03949.15 EAY01193.1 - 2.7e-88 295.6 0.4 3.3e-88 295.3 0.4 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAY01193.1 - 2.4e-69 232.8 0.0 4e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Arb2 PF09757.9 EAY01193.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Arb2 domain AlaDh_PNT_C PF01262.21 EAY01193.1 - 0.2 10.9 1.1 1.7 7.9 0.0 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 EAY01194.1 - 1.1e-52 179.0 0.0 1.5e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01194.1 - 3.3e-30 105.2 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01194.1 - 1.9e-05 24.1 0.0 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAY01194.1 - 0.00035 19.7 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EAY01194.1 - 0.00079 19.4 0.1 0.0063 16.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAY01194.1 - 0.0024 16.9 0.0 0.0047 15.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY01194.1 - 0.0095 15.3 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3755 PF12579.8 EAY01194.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) DUF4278 PF14105.6 EAY01196.1 - 0.1 13.0 0.1 0.33 11.4 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) Peptidase_M8 PF01457.16 EAY01197.1 - 8.8e-06 24.7 0.1 1.2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EAY01198.1 - 0.0084 14.8 0.0 0.02 13.6 0.0 1.8 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EAY01199.1 - 0.0097 14.6 1.5 0.021 13.5 1.2 1.6 1 1 1 2 2 2 1 Leishmanolysin PRIMA1 PF16101.5 EAY01199.1 - 0.063 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SKG6 PF08693.10 EAY01199.1 - 1.6 8.2 6.9 2.5 7.6 6.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GPS2_interact PF15784.5 EAY01202.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01202.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Beach PF02138.18 EAY01203.1 - 4.3e-60 203.4 8.7 4.3e-60 203.4 8.7 2.0 2 0 0 2 2 2 1 Beige/BEACH domain Med31 PF05669.12 EAY01203.1 - 0.056 13.4 0.1 0.056 13.4 0.1 3.2 2 0 0 2 2 2 0 SOH1 KilA-N PF04383.13 EAY01204.1 - 1.9e-33 114.6 0.1 2.6e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAY01204.1 - 0.031 14.2 0.2 0.037 14.0 0.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF3839 PF12943.7 EAY01205.1 - 2.4e-156 518.3 12.1 3e-156 518.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAY01205.1 - 0.11 12.8 0.2 1.8 8.9 0.1 2.9 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAY01205.1 - 1 9.8 6.3 5.5 7.5 0.5 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tup_N PF08581.10 EAY01205.1 - 7.8 6.9 8.2 12 6.3 0.1 3.9 4 1 1 5 5 5 0 Tup N-terminal PTR PF12789.7 EAY01207.1 - 3.1e-05 23.9 0.6 3.1e-05 23.9 0.6 3.4 4 0 0 4 4 4 1 Phage tail repeat like DUF445 PF04286.12 EAY01207.1 - 0.0047 16.8 6.6 0.0066 16.3 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1048 PF06304.11 EAY01207.1 - 0.039 14.4 0.6 0.12 12.9 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF4116 PF13475.6 EAY01207.1 - 0.06 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAY01207.1 - 0.087 13.3 2.9 0.17 12.3 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) DUF1493 PF07377.12 EAY01208.1 - 0.075 13.5 0.7 0.16 12.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY01209.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY01210.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Gly_rich PF12810.7 EAY01211.1 - 1.1e-10 41.9 30.1 2.7e-10 40.6 30.1 1.7 1 1 0 1 1 1 1 Glycine rich protein Furin-like_2 PF15913.5 EAY01211.1 - 4.4e-05 23.6 60.5 0.025 14.7 6.1 4.1 1 1 3 4 4 4 4 Furin-like repeat, cysteine-rich NMD3 PF04981.13 EAY01212.1 - 6.8e-59 199.3 6.6 1.1e-58 198.6 6.6 1.3 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.11 EAY01212.1 - 0.058 13.7 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Nif11 domain MOSC PF03473.17 EAY01212.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 MOSC domain YyzF PF14116.6 EAY01212.1 - 0.27 11.3 2.8 1.2 9.3 0.5 2.5 2 0 0 2 2 2 0 YyzF-like protein Pkinase PF00069.25 EAY01213.1 - 3.2e-61 207.0 0.1 4.1e-61 206.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01213.1 - 5.2e-39 134.1 0.0 6.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01213.1 - 6.5e-09 35.5 0.0 2.5e-07 30.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EAY01213.1 - 9.4e-07 28.4 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY01213.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAY01213.1 - 0.0015 18.1 0.2 0.052 13.1 0.0 2.2 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EAY01213.1 - 0.0024 17.5 0.9 0.0033 17.1 0.1 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EAY01213.1 - 0.0051 15.6 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAY01213.1 - 0.0064 16.1 0.1 0.018 14.7 0.1 1.8 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 EAY01213.1 - 0.016 14.0 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MA3 PF02847.17 EAY01213.1 - 0.032 14.2 0.3 0.21 11.6 0.0 2.4 3 0 0 3 3 3 0 MA3 domain RuvB_C PF05491.13 EAY01214.1 - 0.15 11.9 0.3 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HECT PF00632.25 EAY01216.1 - 5e-21 75.5 0.0 6.1e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ABC2_membrane_3 PF12698.7 EAY01218.1 - 0.025 13.7 0.3 0.049 12.7 0.2 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF5305 PF17231.2 EAY01218.1 - 0.041 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) AMP-binding PF00501.28 EAY01219.1 - 2.1e-71 240.8 0.0 2.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SF3a60_bindingd PF12108.8 EAY01219.1 - 0.093 12.6 0.9 0.27 11.1 0.9 1.8 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Orf78 PF06024.12 EAY01220.1 - 0.028 14.7 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Glyco_hydro_5_C PF18564.1 EAY01220.1 - 0.054 14.0 0.4 0.88 10.2 0.1 2.7 2 1 0 3 3 3 0 Glycoside hydrolase family 5 C-terminal domain COX6C PF02937.15 EAY01220.1 - 0.14 12.3 2.5 0.3 11.3 2.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF2749 PF10907.8 EAY01220.1 - 1.9 8.7 4.0 0.43 10.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) FeoB_associated PF12669.7 EAY01220.1 - 4.9 7.6 5.9 11 6.5 5.9 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Methyltransf_21 PF05050.12 EAY01221.1 - 3.5e-08 33.7 0.2 8e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain F5_F8_type_C PF00754.25 EAY01222.1 - 1.5e-06 28.4 0.1 2.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain ABC_tran PF00005.27 EAY01223.1 - 2.2e-25 89.8 0.0 7.4e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EAY01223.1 - 6.1e-10 38.7 28.5 9.3e-10 38.1 28.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAY01223.1 - 4.6e-07 29.9 4.8 0.00062 19.7 0.3 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAY01223.1 - 0.0052 17.3 0.4 0.015 15.8 0.4 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAY01223.1 - 0.013 15.2 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAY01223.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ToxS PF17323.2 EAY01223.1 - 0.076 12.7 0.2 0.28 10.8 0.2 1.9 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS Zeta_toxin PF06414.12 EAY01223.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 EAY01223.1 - 0.21 11.0 6.2 0.74 9.2 1.5 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EAY01224.1 - 1.3e-30 106.7 21.8 2.1e-30 106.0 21.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EAY01224.1 - 1.2e-28 100.3 0.0 2.3e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAY01224.1 - 1.8e-13 51.0 0.1 6.2e-07 29.5 0.0 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAY01224.1 - 1.3e-06 28.1 0.8 0.0069 15.8 0.0 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAY01224.1 - 0.00019 21.4 0.0 0.00052 20.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EAY01224.1 - 0.0019 18.0 7.9 0.033 13.9 0.5 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 EAY01224.1 - 0.01 16.4 2.1 0.035 14.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAY01224.1 - 0.022 15.3 0.0 9.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAY01224.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EAY01224.1 - 0.088 12.6 1.8 0.089 12.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NFACT-R_1 PF05670.13 EAY01225.1 - 3e-13 50.4 0.0 3.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 EAY01225.1 - 3.4e-06 27.2 0.0 4.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain LRR_5 PF13306.6 EAY01226.1 - 3.8e-148 486.0 90.5 4.8e-29 100.9 6.9 8.2 2 2 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01226.1 - 5.5e-24 83.7 10.3 0.0017 18.0 0.3 10.7 7 3 5 12 12 12 8 Leucine rich repeat DUF4989 PF16379.5 EAY01228.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) Beach PF02138.18 EAY01230.1 - 1.2e-57 195.4 8.4 1.2e-57 195.4 8.4 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF3891 PF13030.6 EAY01230.1 - 9.7 5.9 9.8 0.095 12.5 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3891) Chlam_PMP PF02415.17 EAY01231.1 - 0.012 16.1 27.9 0.036 14.6 0.1 6.9 6 1 1 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 EAY01232.1 - 0.032 14.7 0.7 0.032 14.7 0.7 7.4 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PMP1_2 PF08114.11 EAY01232.1 - 0.056 13.2 1.0 0.12 12.2 1.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family TMEM132D_C PF15706.5 EAY01232.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Exo_endo_phos PF03372.23 EAY01233.1 - 7.6e-08 32.2 0.0 1.7e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRP54 PF00448.22 EAY01234.1 - 1.1e-70 237.2 1.8 1.5e-70 236.9 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EAY01234.1 - 1.1e-17 64.4 1.8 1.1e-17 64.4 1.8 2.5 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EAY01234.1 - 8.9e-09 35.5 0.0 2.4e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EAY01234.1 - 1.1e-06 28.3 1.9 1.3e-05 24.8 0.6 2.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EAY01234.1 - 9.1e-05 22.5 0.0 0.0012 18.9 0.0 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EAY01234.1 - 0.00028 21.3 0.8 0.001 19.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAY01234.1 - 0.00049 20.3 0.0 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EAY01234.1 - 0.0037 16.3 0.7 0.022 13.8 0.0 2.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EAY01234.1 - 0.0064 16.4 0.7 0.04 13.8 0.7 2.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EAY01234.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EAY01234.1 - 0.011 16.3 0.1 0.19 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAY01234.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EAY01234.1 - 0.016 14.9 0.0 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAY01234.1 - 0.024 14.4 3.9 3.6 7.3 0.1 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_31 PF13614.6 EAY01234.1 - 0.025 14.5 7.1 0.16 11.8 0.1 3.6 2 2 0 3 3 3 0 AAA domain APS_kinase PF01583.20 EAY01234.1 - 0.039 13.9 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MipZ PF09140.11 EAY01234.1 - 0.055 12.7 0.4 2.9 7.1 0.2 2.9 2 1 0 2 2 2 0 ATPase MipZ DUF1611 PF07755.11 EAY01234.1 - 0.064 12.5 1.3 3.1 7.0 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 EAY01234.1 - 0.091 12.6 1.4 17 5.2 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EAY01234.1 - 0.098 12.4 0.2 0.098 12.4 0.2 2.0 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EAY01234.1 - 0.13 12.8 1.3 0.57 10.7 1.3 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAY01234.1 - 0.18 11.9 4.1 0.39 10.8 0.4 3.3 3 2 0 3 3 3 0 50S ribosome-binding GTPase SRPRB PF09439.10 EAY01234.1 - 0.42 10.0 3.7 12 5.3 0.1 3.2 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EAY01234.1 - 0.73 9.7 3.5 20 5.0 3.5 2.5 1 1 0 1 1 1 0 NTPase AAA PF00004.29 EAY01234.1 - 0.75 10.2 7.1 12 6.4 0.9 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TaqI_C PF12950.7 EAY01235.1 - 0.03 14.4 10.3 0.048 13.7 10.3 1.6 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain Ank_2 PF12796.7 EAY01236.1 - 1e-16 61.3 0.9 7.9e-10 39.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01236.1 - 1.3e-08 34.3 3.8 0.13 12.9 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EAY01236.1 - 2.1e-07 31.3 0.2 0.00052 20.5 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01236.1 - 7.1e-06 26.2 1.0 0.00017 21.8 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01236.1 - 1.2e-05 25.6 0.1 0.39 11.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF2624 PF11116.8 EAY01236.1 - 0.0064 17.4 1.1 0.026 15.4 1.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2624) DUF1948 PF09185.10 EAY01236.1 - 0.017 15.0 1.9 0.042 13.7 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1948) Symplekin_C PF12295.8 EAY01236.1 - 0.037 14.1 0.7 0.085 12.9 0.7 1.7 1 1 0 1 1 1 0 Symplekin tight junction protein C terminal Anti-adapt_IraP PF10796.9 EAY01236.1 - 1.4 9.6 6.5 49 4.6 0.3 3.2 1 1 1 3 3 3 0 Sigma-S stabilisation anti-adaptor protein Pkinase PF00069.25 EAY01237.1 - 2e-39 135.6 0.0 3.1e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01237.1 - 3.5e-31 108.4 0.0 6.2e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01237.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Radical_SAM PF04055.21 EAY01238.1 - 6.4e-14 52.7 0.0 1.2e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF3294 PF07957.11 EAY01239.1 - 0.019 14.7 0.5 0.019 14.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) Cnn_1N PF07989.11 EAY01239.1 - 0.025 14.7 0.4 0.025 14.7 0.4 2.5 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Noelin-1 PF12308.8 EAY01239.1 - 3.9 7.5 6.8 4.2 7.4 2.5 2.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein Dor1 PF04124.12 EAY01241.1 - 9.9e-05 21.2 6.0 0.00011 21.0 6.0 1.0 1 0 0 1 1 1 1 Dor1-like family Sec34 PF04136.15 EAY01241.1 - 0.00043 20.2 10.0 0.0037 17.2 3.1 2.1 1 1 1 2 2 2 2 Sec34-like family DUF2451 PF10474.9 EAY01241.1 - 0.0018 18.1 1.0 0.0019 18.0 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF5344 PF17279.2 EAY01241.1 - 0.0018 18.8 6.4 0.0029 18.1 4.5 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5344) FliJ PF02050.16 EAY01241.1 - 0.0031 17.7 2.3 0.0038 17.4 2.3 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein Med10 PF09748.9 EAY01241.1 - 0.0038 17.2 2.7 0.0047 16.9 2.7 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex EzrA PF06160.12 EAY01241.1 - 0.0086 14.3 8.5 0.01 14.1 8.5 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mod_r PF07200.13 EAY01241.1 - 0.025 14.7 8.5 0.42 10.7 0.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Syntaxin-6_N PF09177.11 EAY01241.1 - 0.055 14.0 5.3 1.2 9.7 5.3 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal WXG100 PF06013.12 EAY01241.1 - 0.058 13.6 1.2 0.096 12.9 0.4 1.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF948 PF06103.11 EAY01241.1 - 0.061 13.6 3.4 0.43 10.9 2.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 EAY01241.1 - 0.092 12.6 5.2 0.1 12.4 4.4 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YlqD PF11068.8 EAY01241.1 - 0.1 13.0 5.7 0.11 12.8 5.7 1.1 1 0 0 1 1 1 0 YlqD protein DUF1241 PF06840.11 EAY01241.1 - 0.1 12.2 3.3 0.065 12.9 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) DUF4407 PF14362.6 EAY01241.1 - 0.11 11.8 1.7 0.14 11.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EAY01241.1 - 0.12 12.5 4.9 0.16 12.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EAY01241.1 - 0.12 12.9 9.3 1.5 9.3 1.4 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EAY01241.1 - 0.22 11.8 7.9 0.49 10.7 0.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.16 EAY01241.1 - 0.29 10.0 5.7 0.32 9.8 5.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FlxA PF14282.6 EAY01241.1 - 0.49 10.4 12.6 0.12 12.4 5.9 2.0 1 1 1 2 2 2 0 FlxA-like protein DUF3450 PF11932.8 EAY01241.1 - 0.49 9.6 7.4 0.39 10.0 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EAY01241.1 - 1.3 9.2 8.0 6.5 6.9 0.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EAY01241.1 - 1.7 9.3 5.9 9 7.0 3.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA LPP PF04728.13 EAY01241.1 - 3.8 8.0 6.7 17 5.9 0.2 2.7 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Synaptobrevin PF00957.21 EAY01241.1 - 8.9 6.2 10.0 1.3 8.8 2.9 2.3 2 1 0 2 2 2 0 Synaptobrevin zf-HIT PF04438.16 EAY01242.1 - 8.6e-07 28.7 14.8 1.5e-06 27.9 14.8 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF702 PF05142.12 EAY01242.1 - 0.05 14.1 8.6 0.078 13.5 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) zf-C3HC4_3 PF13920.6 EAY01242.1 - 2.4 8.1 16.3 4.5 7.2 16.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 EAY01242.1 - 8.6 4.1 10.0 13 3.5 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Mitofilin PF09731.9 EAY01243.1 - 0.21 10.4 2.1 0.49 9.2 2.1 1.5 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Ank_2 PF12796.7 EAY01244.1 - 3.1e-54 181.5 16.6 9.5e-16 58.2 0.1 6.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01244.1 - 9.2e-53 176.0 14.7 1.7e-07 31.6 0.1 12.2 5 3 7 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAY01244.1 - 6.3e-47 156.1 0.8 9.5e-06 25.8 0.0 11.0 10 1 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EAY01244.1 - 1.9e-39 129.1 19.1 0.00014 22.0 0.0 14.0 15 1 1 16 16 16 8 Ankyrin repeat Ank_5 PF13857.6 EAY01244.1 - 1.2e-37 127.5 9.8 4.3e-08 33.3 0.1 7.3 4 2 2 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01244.1 - 7.5e-34 115.5 10.1 6.8e-33 112.5 6.8 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) RNase_PH PF01138.21 EAY01245.1 - 7.3e-05 23.3 0.0 0.0001 22.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TTRAP PF14203.6 EAY01246.1 - 0.016 15.2 0.1 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein PDEase_I PF00233.19 EAY01247.1 - 0.00016 21.5 0.2 0.00057 19.7 0.1 1.9 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ParA PF10609.9 EAY01249.1 - 7.6e-61 205.7 0.3 8.8e-61 205.5 0.3 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 EAY01249.1 - 6e-09 36.1 2.3 0.00012 22.1 1.3 2.2 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 EAY01249.1 - 1.8e-08 34.5 0.0 2.7e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EAY01249.1 - 2.6e-07 30.2 3.4 0.0071 15.6 0.7 2.6 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.11 EAY01249.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EAY01249.1 - 0.00097 18.7 0.1 0.66 9.4 0.0 2.2 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EAY01249.1 - 0.001 18.6 0.3 0.008 15.7 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EAY01249.1 - 0.08 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EAY01249.1 - 0.18 11.1 0.1 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 VirC1 protein Ank_2 PF12796.7 EAY01250.1 - 3e-34 117.5 0.0 2.5e-18 66.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01250.1 - 6.1e-23 80.2 0.0 0.0016 18.8 0.0 5.6 4 1 1 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EAY01250.1 - 1e-22 80.2 0.0 1.4e-07 31.9 0.0 4.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01250.1 - 1.6e-21 76.1 0.0 2.6e-05 24.4 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01250.1 - 7.4e-21 72.0 0.0 0.0061 17.0 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat DUF3083 PF11281.8 EAY01250.1 - 0.0037 16.6 0.3 0.054 12.8 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3083) DUF1664 PF07889.12 EAY01250.1 - 0.018 15.1 5.3 0.033 14.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAY01250.1 - 0.072 13.3 9.2 0.028 14.6 5.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MCU PF04678.13 EAY01250.1 - 0.17 12.0 1.5 0.33 11.0 1.5 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2115 PF09888.9 EAY01250.1 - 0.17 12.4 10.6 0.43 11.1 5.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) NuA4 PF09340.10 EAY01250.1 - 0.22 11.4 3.6 0.59 10.0 3.6 1.8 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 PI_PP_I PF18363.1 EAY01250.1 - 0.45 10.7 4.0 1.2 9.4 2.7 2.4 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain TMPIT PF07851.13 EAY01250.1 - 0.77 8.9 6.7 1.3 8.2 6.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Nas2_N PF18265.1 EAY01250.1 - 1 9.3 6.4 0.27 11.2 2.0 2.4 2 1 0 2 2 2 0 Nas2 N_terminal domain SlyX PF04102.12 EAY01250.1 - 2.7 8.7 7.1 3.9 8.2 5.7 1.9 2 0 0 2 2 2 0 SlyX YabA PF06156.13 EAY01250.1 - 2.7 8.7 9.3 4.2 8.1 8.3 1.9 1 1 0 1 1 1 0 Initiation control protein YabA FliD_N PF02465.18 EAY01250.1 - 8.1 7.2 7.7 5.1 7.8 4.7 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ax_dynein_light PF10211.9 EAY01251.1 - 2.1e-06 27.8 34.8 2e-05 24.6 16.7 4.0 2 1 1 3 3 3 2 Axonemal dynein light chain Kunitz_BPTI PF00014.23 EAY01251.1 - 0.012 15.8 0.4 0.085 13.1 0.0 2.2 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain HisKA_3 PF07730.13 EAY01251.1 - 0.059 13.9 1.7 0.39 11.3 0.8 3.0 2 0 0 2 2 2 0 Histidine kinase CDPS PF16715.5 EAY01251.1 - 0.34 10.5 4.6 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Cyclodipeptide synthase ATG101 PF07855.12 EAY01251.1 - 1.1 9.2 6.7 10 6.1 4.8 2.8 2 0 0 2 2 2 0 Autophagy-related protein 101 Lebercilin PF15619.6 EAY01251.1 - 1.9 8.1 34.5 0.031 13.9 19.5 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Comm PF15957.5 EAY01252.1 - 0.061 13.7 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Commissureless VIT_2 PF13757.6 EAY01252.1 - 5 7.1 5.2 3.6 7.6 0.9 2.4 2 1 1 3 3 3 0 Vault protein inter-alpha-trypsin domain Ank_2 PF12796.7 EAY01253.1 - 2.7e-70 233.0 1.4 1.1e-19 70.8 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01253.1 - 1.6e-36 123.1 0.0 8.2e-05 22.9 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAY01253.1 - 5.9e-35 118.9 0.2 2.9e-07 30.6 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01253.1 - 1e-30 105.7 0.0 3e-08 34.0 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01253.1 - 2e-30 101.4 0.0 0.0024 18.2 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat DUF1147 PF06615.11 EAY01253.1 - 0.0027 17.7 1.5 2.8 8.1 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1147) DUF1664 PF07889.12 EAY01253.1 - 0.0082 16.2 4.8 0.015 15.4 4.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DMT_6 PF04342.12 EAY01253.1 - 0.015 15.5 0.2 13 6.0 0.0 3.8 1 1 2 3 3 3 0 Putative member of DMT superfamily (DUF486) Adenine_glyco PF03352.13 EAY01253.1 - 0.03 14.1 2.9 0.041 13.7 2.0 1.6 1 1 0 1 1 1 0 Methyladenine glycosylase 7TMR-HDED PF07697.11 EAY01253.1 - 0.034 14.3 1.8 0.068 13.3 1.8 1.4 1 0 0 1 1 1 0 7TM-HD extracellular Csm2_III-A PF03750.13 EAY01253.1 - 0.14 13.0 7.2 0.35 11.7 6.6 1.9 1 1 0 1 1 1 0 Csm2 Type III-A Fib_alpha PF08702.10 EAY01253.1 - 0.35 11.1 11.2 0.058 13.6 6.4 2.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF2115 PF09888.9 EAY01253.1 - 0.72 10.4 10.1 0.69 10.4 5.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TMPIT PF07851.13 EAY01253.1 - 0.8 8.9 6.2 1.3 8.2 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Nas2_N PF18265.1 EAY01253.1 - 1.5 8.8 5.2 0.65 9.9 1.8 2.3 2 1 0 2 2 1 0 Nas2 N_terminal domain SlyX PF04102.12 EAY01253.1 - 2.6 8.7 6.8 4.2 8.0 5.6 1.9 2 0 0 2 2 2 0 SlyX YabA PF06156.13 EAY01253.1 - 2.8 8.6 8.4 6.2 7.5 8.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 EAY01253.1 - 5.4 7.5 13.4 4.3 7.9 11.5 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Cation_efflux PF01545.21 EAY01254.1 - 1.5e-24 86.8 12.5 1.8e-24 86.6 12.5 1.1 1 0 0 1 1 1 1 Cation efflux family TetR_C_10 PF16295.5 EAY01255.1 - 0.022 15.0 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain eIF-1a PF01176.19 EAY01256.1 - 1.7e-17 63.0 0.1 2.7e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EAY01256.1 - 0.034 13.9 0.2 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 RsgA N-terminal domain Pro_isomerase PF00160.21 EAY01257.1 - 7.4e-45 153.0 0.0 8.4e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Vps39_2 PF10367.9 EAY01259.1 - 4.5e-11 43.2 0.7 1.2e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 DUF2685 PF10886.8 EAY01259.1 - 0.057 13.6 0.5 0.16 12.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) CCDC-167 PF15188.6 EAY01259.1 - 0.16 12.3 2.2 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3447 PF11929.8 EAY01260.1 - 1.8e-36 123.9 3.7 1.8e-36 123.9 3.7 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01260.1 - 0.024 15.2 0.6 0.75 10.4 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF4200 PF13863.6 EAY01261.1 - 1.2e-22 80.6 15.5 1.2e-22 80.6 15.5 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) DUF4326 PF14216.6 EAY01261.1 - 0.71 10.6 3.1 12 6.7 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4326) DUF1612 PF07756.12 EAY01261.1 - 1.7 8.9 8.4 0.057 13.7 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) Chromo PF00385.24 EAY01262.1 - 1.9e-13 50.1 1.4 3e-13 49.4 1.4 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WAC_Acf1_DNA_bd PF10537.9 EAY01262.1 - 0.057 13.9 0.1 0.089 13.3 0.1 1.3 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Chromo_shadow PF01393.19 EAY01262.1 - 0.74 9.9 3.4 0.36 10.9 0.4 1.9 2 0 0 2 2 2 0 Chromo shadow domain Peptidase_M14 PF00246.24 EAY01263.1 - 1.5e-16 61.1 0.0 9.6e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EAY01263.1 - 6.3e-10 39.4 2.5 1.2e-09 38.5 2.5 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Ribosomal_L36e PF01158.18 EAY01264.1 - 8.1e-21 74.1 2.4 9.7e-21 73.8 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EAY01264.1 - 0.05 13.4 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Ank_2 PF12796.7 EAY01265.1 - 1.1e-98 324.0 55.9 1.1e-17 64.4 5.1 5.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01265.1 - 2.9e-82 267.8 9.2 1.1e-08 35.1 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 EAY01265.1 - 3e-82 270.0 13.7 6.3e-12 45.8 0.1 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01265.1 - 1.1e-67 215.9 12.9 2e-07 30.7 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EAY01265.1 - 3.8e-62 205.5 11.0 1.3e-12 47.7 0.1 5.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Mic1 PF07035.12 EAY01265.1 - 2.1e-07 30.8 0.0 0.055 13.2 0.0 5.1 4 2 0 5 5 5 1 Colon cancer-associated protein Mic1-like PAZ_siRNAbind PF12212.8 EAY01265.1 - 1.3e-05 25.1 4.0 20 5.0 0.0 6.4 1 1 4 7 7 7 0 PAZ domain RNase_PH_C PF03725.15 EAY01265.1 - 1.5e-05 25.0 1.3 7.2 6.7 0.0 5.9 1 1 2 5 5 5 1 3' exoribonuclease family, domain 2 MTES_1575 PF18741.1 EAY01265.1 - 5.4e-05 23.3 3.7 5.5 7.2 0.0 5.4 3 1 0 5 5 5 1 REase_MTES_1575 CCDC84 PF14968.6 EAY01265.1 - 0.001 18.8 13.5 2.1 7.9 2.2 5.4 1 1 3 4 4 4 3 Coiled coil protein 84 Stap_Strp_toxin PF01123.20 EAY01265.1 - 0.0023 18.7 11.2 6.2 7.8 0.1 5.0 3 1 2 5 5 5 1 Staphylococcal/Streptococcal toxin, OB-fold domain SAB PF04382.13 EAY01265.1 - 0.0064 16.5 14.7 35 4.6 0.0 8.1 8 1 1 9 9 9 0 SAB domain P2_Phage_GpR PF06891.11 EAY01265.1 - 0.011 15.8 2.2 28 4.8 0.0 4.2 4 1 0 4 4 4 0 P2 phage tail completion protein R (GpR) GST_N_4 PF17172.4 EAY01265.1 - 0.016 15.9 4.0 54 4.6 0.0 4.4 4 1 1 5 5 5 0 Glutathione S-transferase N-terminal domain DUF4796 PF16044.5 EAY01265.1 - 0.04 13.5 6.4 11 5.5 0.1 4.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4796) Env-gp36 PF09590.10 EAY01265.1 - 0.067 11.6 2.2 16 3.8 0.1 3.4 1 1 2 4 4 4 0 Lentivirus surface glycoprotein S10_plectin PF03501.15 EAY01265.1 - 2.2 8.4 5.8 22 5.2 0.1 4.5 5 1 1 6 6 6 0 Plectin/S10 domain PH_8 PF15409.6 EAY01265.1 - 2.4 8.5 5.5 48 4.3 0.0 4.8 1 1 7 8 8 8 0 Pleckstrin homology domain DUF2149 PF09919.9 EAY01265.1 - 5.5 7.3 13.0 79 3.6 0.6 5.4 3 1 5 8 8 8 0 Uncharacterized conserved protein (DUF2149) DUF3447 PF11929.8 EAY01266.1 - 1.1e-38 131.0 8.0 1.1e-38 131.0 8.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01266.1 - 3.8e-33 113.9 13.9 1e-16 61.2 0.7 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01266.1 - 2.1e-25 88.7 2.5 1.7e-07 31.6 0.0 5.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01266.1 - 3.3e-23 81.1 0.0 1.1e-07 32.0 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAY01266.1 - 1e-21 76.7 0.4 2.7e-11 43.5 0.0 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01266.1 - 2.3e-17 61.3 4.3 8.6e-06 25.7 0.1 6.4 6 0 0 6 6 6 2 Ankyrin repeat Gly_rich PF12810.7 EAY01267.1 - 6.4e-50 170.3 33.2 7.8e-50 170.1 33.2 1.0 1 0 0 1 1 1 1 Glycine rich protein TMP PF05017.14 EAY01269.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY01270.1 - 0.018 15.5 0.8 0.036 14.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY01271.1 - 2.7e-25 88.2 10.2 2.7e-25 88.2 10.2 4.5 5 1 1 6 6 5 1 Phage tail repeat like DUF3839 PF12943.7 EAY01272.1 - 2.7e-157 521.4 13.5 3.4e-157 521.1 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY01272.1 - 5.7 7.5 9.4 1.9 9.0 1.1 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4841 PF16129.5 EAY01274.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) ARA70 PF12489.8 EAY01275.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator MULE PF10551.9 EAY01276.1 - 1.4e-10 41.4 0.2 4e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAY01276.1 - 0.026 13.4 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family CK_II_beta PF01214.18 EAY01278.1 - 3.9e-43 147.4 2.6 4.6e-43 147.1 2.6 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit UPF0242 PF06785.11 EAY01279.1 - 0.052 13.7 3.2 0.06 13.4 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Aminotran_5 PF00266.19 EAY01280.1 - 3.2e-13 49.4 0.0 8.5e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EAY01280.1 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EAY01280.1 - 9.7e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain YcxB PF14317.6 EAY01280.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 YcxB-like protein BTB PF00651.31 EAY01281.1 - 0.00047 20.4 0.7 0.0011 19.2 0.1 1.9 3 0 0 3 3 3 1 BTB/POZ domain Flu_M1 PF00598.19 EAY01281.1 - 0.061 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) NPL PF17800.1 EAY01282.1 - 0.051 14.1 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin-like domain DUF789 PF05623.12 EAY01284.1 - 0.3 10.7 6.0 0.44 10.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) SHIPPO-rpt PF07004.12 EAY01284.1 - 8.2 7.5 15.5 5.1 8.2 0.1 4.7 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat Ras PF00071.22 EAY01285.1 - 1.7e-54 183.8 1.2 1.9e-54 183.6 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01285.1 - 6.6e-31 107.0 0.5 8.8e-31 106.6 0.5 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01285.1 - 3.5e-11 42.9 0.3 4.1e-11 42.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY01285.1 - 0.00057 19.9 0.1 0.00078 19.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAY01285.1 - 0.002 18.1 0.6 0.52 10.2 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAY01285.1 - 0.012 15.0 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EAY01285.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAY01285.1 - 0.12 12.3 0.1 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 NTPase MCM PF00493.23 EAY01285.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Kinesin PF00225.23 EAY01286.1 - 2.3e-105 352.2 0.0 2.3e-105 352.2 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EAY01286.1 - 3.1e-26 92.1 0.4 1.3e-25 90.0 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Mto2_bdg PF12808.7 EAY01287.1 - 0.049 13.9 7.5 0.48 10.8 2.2 3.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMF_TATA_bd PF12325.8 EAY01287.1 - 0.079 13.2 29.5 0.65 10.2 3.6 4.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EAY01287.1 - 0.086 12.2 20.3 0.26 10.6 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GTP-bdg_M PF16360.5 EAY01287.1 - 0.19 12.3 10.6 3.2 8.4 0.3 4.2 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region Spc7 PF08317.11 EAY01287.1 - 0.3 9.9 28.7 0.43 9.4 10.8 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Rx_N PF18052.1 EAY01287.1 - 1.4 9.2 8.6 20 5.5 0.1 3.9 2 1 1 3 3 3 0 Rx N-terminal domain Med10 PF09748.9 EAY01287.1 - 1.6 8.7 13.4 0.82 9.6 0.5 3.7 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex GIT_CC PF16559.5 EAY01287.1 - 1.7 8.6 19.2 4.1 7.3 1.4 5.0 5 1 1 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5320 PF17253.2 EAY01287.1 - 3.6 8.7 7.8 13 6.9 0.7 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Prominin PF05478.11 EAY01287.1 - 3.9 5.3 17.6 0.53 8.2 10.4 2.1 1 1 1 2 2 2 0 Prominin Jnk-SapK_ap_N PF09744.9 EAY01287.1 - 3.9 7.7 21.7 15 5.8 6.0 3.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 EAY01287.1 - 6.5 7.3 20.6 24 5.5 2.1 4.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 EAY01287.1 - 7.1 6.9 17.5 14 6.0 0.3 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper Leu_zip PF15294.6 EAY01287.1 - 8.1 5.9 28.6 8.4 5.8 14.2 2.6 1 1 1 2 2 2 0 Leucine zipper Archease PF01951.16 EAY01288.1 - 2e-38 131.7 0.2 2.3e-38 131.6 0.2 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) TPR_19 PF14559.6 EAY01289.1 - 1.9e-11 44.3 21.3 0.00066 20.1 1.1 6.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAY01289.1 - 6.4e-10 38.4 23.9 0.00026 20.9 0.2 8.3 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAY01289.1 - 1.4e-08 35.2 0.2 0.0051 17.4 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAY01289.1 - 1.4e-07 31.6 24.2 1e-05 25.7 3.4 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EAY01289.1 - 5.9e-06 25.9 20.5 0.057 13.3 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAY01289.1 - 7e-06 26.1 12.0 0.0036 17.3 2.7 3.7 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_8 PF13181.6 EAY01289.1 - 5.3e-05 23.1 20.5 0.012 15.8 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAY01289.1 - 0.00034 20.8 12.5 6.2 7.2 0.0 6.9 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAY01289.1 - 0.00063 19.6 6.7 0.12 12.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAY01289.1 - 0.0047 16.6 0.9 2.5 7.8 0.1 3.7 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EAY01289.1 - 0.027 15.1 15.5 1.9 9.3 0.1 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat PPR_2 PF13041.6 EAY01289.1 - 0.19 11.9 4.2 0.4 10.9 0.2 3.7 3 1 0 3 3 3 0 PPR repeat family Pneumovirus_M2 PF06436.11 EAY01289.1 - 0.35 10.4 2.8 1.2 8.6 0.4 2.8 3 0 0 3 3 3 0 Pneumovirus matrix protein 2 (M2) DUF4558 PF15104.6 EAY01290.1 - 2.1e-08 34.1 4.2 2.9e-08 33.7 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) Fer4_20 PF14691.6 EAY01291.1 - 0.12 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster PH PF00169.29 EAY01292.1 - 1.6e-08 35.0 0.4 4.4e-08 33.6 0.4 1.8 1 0 0 1 1 1 1 PH domain DUF1450 PF07293.11 EAY01292.1 - 0.069 13.0 1.9 1.5 8.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Mcp5_PH PF12814.7 EAY01292.1 - 0.13 12.4 1.3 0.23 11.6 0.2 2.0 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology GST_C PF00043.25 EAY01293.1 - 0.00063 19.9 1.8 3.7 7.8 0.0 4.0 1 1 2 3 3 3 2 Glutathione S-transferase, C-terminal domain DUF4795 PF16043.5 EAY01293.1 - 0.0022 17.6 8.3 0.97 9.0 0.8 3.7 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) ESAG1 PF03238.13 EAY01293.1 - 0.0037 16.8 8.3 0.77 9.2 0.4 4.1 1 1 3 4 4 4 2 ESAG protein PH_3 PF14593.6 EAY01293.1 - 0.1 12.7 3.4 3.8 7.7 0.0 3.3 3 0 0 3 3 3 0 PH domain Whi5 PF08528.11 EAY01293.1 - 0.22 11.2 2.8 81 3.0 0.1 3.8 3 0 0 3 3 3 0 Whi5 like Ribosomal_L12 PF00542.19 EAY01293.1 - 0.98 9.8 3.7 46 4.5 0.0 3.4 3 1 1 4 4 4 0 Ribosomal protein L7/L12 C-terminal domain Apolipoprotein PF01442.18 EAY01294.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Arm_2 PF04826.13 EAY01295.1 - 1.6e-05 24.5 3.7 1.6e-05 24.5 3.7 2.1 2 0 0 2 2 2 1 Armadillo-like NanE PF04131.14 EAY01295.1 - 0.14 11.4 0.2 0.27 10.4 0.2 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase CDtoxinA PF03498.14 EAY01295.1 - 0.24 11.0 2.2 1.7 8.2 0.1 3.0 2 1 1 4 4 4 0 Cytolethal distending toxin A/C domain DUF1981 PF09324.10 EAY01295.1 - 0.54 10.2 8.0 7.1 6.6 0.2 3.8 1 1 2 4 4 4 0 Domain of unknown function (DUF1981) MOZ_SAS PF01853.18 EAY01296.1 - 6.3e-64 214.9 0.0 1.2e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAY01296.1 - 4.4e-18 64.6 2.1 8.5e-18 63.7 2.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_1 PF00583.25 EAY01296.1 - 0.00017 21.8 0.0 0.00064 20.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Tudor-knot PF11717.8 EAY01296.1 - 0.00036 20.4 1.6 0.00084 19.2 1.6 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EAY01296.1 - 0.0005 20.4 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_jaz PF12171.8 EAY01296.1 - 0.01 16.1 0.9 0.027 14.8 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FR47 PF08445.10 EAY01296.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein HrcA_DNA-bdg PF03444.15 EAY01296.1 - 0.054 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding zf-C2H2_4 PF13894.6 EAY01296.1 - 0.2 12.6 1.9 0.25 12.3 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger FapA PF03961.13 EAY01297.1 - 0.0073 15.0 0.5 0.01 14.4 0.5 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A DASH_Dam1 PF08653.10 EAY01297.1 - 0.034 13.9 0.5 13 5.7 0.0 3.3 3 1 1 4 4 4 0 DASH complex subunit Dam1 KxDL PF10241.9 EAY01297.1 - 0.073 13.3 0.7 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein BLOC1_2 PF10046.9 EAY01297.1 - 3.3 8.1 6.0 4.5 7.6 0.8 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPT PF03151.16 EAY01298.1 - 1.8e-06 27.6 18.7 2.5e-06 27.0 18.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family S_4TM PF18159.1 EAY01298.1 - 0.13 11.5 0.0 0.13 11.5 0.0 3.0 2 2 1 3 3 3 0 SMODS-associating 4TM effector domain TSC22 PF01166.18 EAY01299.1 - 2.2 8.6 7.6 0.49 10.7 2.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Ribosomal_L18 PF17135.4 EAY01300.1 - 2.4e-74 248.8 0.7 2.7e-74 248.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EAY01300.1 - 0.00061 20.5 0.1 0.001 19.7 0.1 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ras PF00071.22 EAY01301.1 - 2.4e-42 144.3 0.2 2.8e-42 144.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01301.1 - 4.9e-25 88.1 0.0 7.6e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01301.1 - 6.7e-11 42.0 0.0 9.5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY01301.1 - 0.00044 20.3 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAY01301.1 - 0.0008 19.0 0.0 0.0022 17.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAY01301.1 - 0.0015 18.0 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAY01301.1 - 0.0039 17.1 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase DNA_pol_E_B PF04042.16 EAY01301.1 - 0.0077 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FeoB_N PF02421.18 EAY01301.1 - 0.025 14.1 0.0 0.5 9.9 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B LCAT PF02450.15 EAY01302.1 - 8.5e-31 107.5 0.9 1.1e-28 100.6 0.0 2.2 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAY01302.1 - 0.00038 19.8 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAY01302.1 - 0.003 17.3 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 2 PGAP1-like protein DUF900 PF05990.12 EAY01302.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TFIIE_beta PF02186.15 EAY01304.1 - 1.8e-09 37.7 0.5 4.2e-09 36.6 0.5 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3447 PF11929.8 EAY01305.1 - 6.7e-12 45.2 1.9 6.7e-12 45.2 1.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY01305.1 - 0.0005 20.3 0.0 2 8.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01305.1 - 0.0026 18.3 0.0 2.2 8.9 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF5365 PF17326.2 EAY01305.1 - 0.047 14.1 2.6 0.13 12.6 2.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Ank_4 PF13637.6 EAY01305.1 - 0.12 13.0 0.0 32 5.2 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01306.1 - 5.2e-54 180.8 2.5 4.7e-17 62.4 0.5 4.4 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01306.1 - 5.6e-46 154.4 4.0 1.2e-13 51.2 0.0 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY01306.1 - 2.4e-37 125.8 8.3 7.7e-06 26.1 0.2 7.5 7 1 1 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAY01306.1 - 4.2e-37 121.9 0.3 0.0001 22.4 0.0 7.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAY01306.1 - 8.8e-34 115.1 1.0 3.1e-09 36.9 0.1 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) DUF4988 PF16378.5 EAY01306.1 - 0.0086 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UDPG_MGDP_dh_C PF03720.15 EAY01306.1 - 0.036 14.5 0.3 9.3 6.7 0.0 3.8 3 2 1 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF4350 PF14258.6 EAY01306.1 - 0.15 12.5 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) AcetylCoA_hydro PF02550.15 EAY01308.1 - 1.4e-44 152.5 0.0 2.1e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EAY01308.1 - 2.2e-40 138.1 0.0 3.6e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF4107 PF13389.6 EAY01312.1 - 1.4e-72 243.1 4.4 1.8e-72 242.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAY01312.1 - 0.22 9.9 0.8 0.31 9.4 0.8 1.2 1 0 0 1 1 1 0 Lipoxygenase Forkhead PF00250.18 EAY01314.1 - 0.022 15.0 0.2 0.025 14.8 0.2 1.2 1 0 0 1 1 1 0 Forkhead domain rve_3 PF13683.6 EAY01316.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain LRR_5 PF13306.6 EAY01317.1 - 4e-141 463.3 95.1 7.2e-32 110.1 12.1 7.1 3 2 4 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01317.1 - 5.3e-22 77.4 3.1 0.0045 16.7 0.0 9.3 6 2 2 9 9 9 6 Leucine rich repeat Big_11 PF18200.1 EAY01317.1 - 0.025 14.5 0.2 0.1 12.5 0.2 2.0 1 0 0 1 1 1 0 Bacterial Ig-like domain LRR_4 PF12799.7 EAY01317.1 - 0.12 12.9 16.7 30 5.2 0.1 7.3 4 1 2 7 7 7 0 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 EAY01317.1 - 0.68 10.1 5.9 2 8.6 0.1 4.4 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Metallophos PF00149.28 EAY01318.1 - 2.1e-09 38.2 1.1 3.6e-09 37.4 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GYD PF08734.11 EAY01318.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 GYD domain PSP PF04046.16 EAY01320.1 - 0.11 12.4 0.8 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY01321.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PTR PF12789.7 EAY01323.1 - 3.4e-05 23.8 0.6 3.4e-05 23.8 0.6 4.8 4 1 0 4 4 4 1 Phage tail repeat like DUF4116 PF13475.6 EAY01323.1 - 0.057 13.2 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF3417 PF11897.8 EAY01323.1 - 0.096 13.1 3.7 0.16 12.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) DUF4795 PF16043.5 EAY01323.1 - 1.4 8.5 21.8 0.085 12.5 7.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAY01323.1 - 1.6 9.1 10.6 0.24 11.7 0.6 3.3 3 0 0 3 3 3 0 Phage tail fibre repeat DUF445 PF04286.12 EAY01323.1 - 2.7 7.7 10.7 4.3 7.1 10.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4108 PF13390.6 EAY01324.1 - 2.7e-62 208.9 8.2 3e-62 208.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Ank_2 PF12796.7 EAY01326.1 - 7.1e-05 23.3 0.1 8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01326.1 - 0.0021 18.6 0.1 0.0032 18.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01326.1 - 0.005 17.1 0.0 0.007 16.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01326.1 - 0.0069 16.8 0.1 0.77 10.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAY01326.1 - 0.013 15.9 0.1 0.093 13.2 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EAY01327.1 - 0.0022 18.6 0.6 0.83 10.3 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NEMO PF11577.8 EAY01327.1 - 0.0051 16.8 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO DUF3447 PF11929.8 EAY01327.1 - 0.016 15.2 15.9 0.38 10.7 0.1 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3447) Latrophilin PF02354.16 EAY01327.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Ank_3 PF13606.6 EAY01327.1 - 0.12 13.0 1.3 98 4.0 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EAY01328.1 - 2.3e-26 92.2 19.5 8.1e-08 32.7 0.5 9.5 4 3 5 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01328.1 - 9.7e-19 65.5 7.5 0.048 14.2 0.0 13.0 14 1 0 14 14 14 3 Ankyrin repeat Ank_4 PF13637.6 EAY01328.1 - 4.7e-15 55.8 12.3 5.5e-05 23.6 0.2 9.6 7 4 4 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01328.1 - 7.4e-09 35.7 0.1 0.12 12.7 0.1 8.1 7 3 3 10 10 10 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01328.1 - 1.5e-05 25.2 4.6 1.9 9.1 0.0 7.0 7 1 0 7 7 7 1 Ankyrin repeat hnRNP_Q_AcD PF18360.1 EAY01328.1 - 0.25 11.3 2.5 12 6.0 0.0 3.7 4 0 0 4 4 4 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Adenine_glyco PF03352.13 EAY01328.1 - 0.37 10.5 4.2 4.1 7.1 0.2 2.6 2 0 0 2 2 2 0 Methyladenine glycosylase Ank_2 PF12796.7 EAY01329.1 - 5.6e-10 39.7 1.7 5.2e-07 30.2 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01329.1 - 3.2e-09 37.2 0.1 0.14 12.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01329.1 - 2.5e-06 27.7 0.3 0.57 10.7 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAY01329.1 - 0.00066 19.9 0.3 9 6.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01329.1 - 0.15 12.7 4.2 12 6.8 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EAY01330.1 - 6.3e-15 55.5 7.3 1.7e-05 25.3 0.1 6.9 4 3 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01330.1 - 1e-11 44.8 0.0 0.034 14.5 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01330.1 - 4e-11 42.1 12.1 0.042 14.4 0.0 10.0 11 0 0 11 11 11 2 Ankyrin repeat Ank_4 PF13637.6 EAY01330.1 - 4.6e-11 43.0 2.4 0.016 15.8 0.0 6.8 7 2 0 7 7 7 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01330.1 - 6.4e-08 32.4 2.8 6.4e-08 32.4 2.8 7.5 7 3 3 10 10 10 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAY01330.1 - 0.00037 20.8 5.2 3.6 8.2 0.0 6.7 9 0 0 9 9 9 2 Ankyrin repeat FdhE PF04216.12 EAY01330.1 - 0.043 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4457 PF14652.6 EAY01331.1 - 7.3e-11 41.9 1.0 3.6e-06 26.4 0.1 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4457) Pkinase PF00069.25 EAY01332.1 - 6.1e-10 38.9 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01332.1 - 2.2e-07 30.5 0.0 2.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01332.1 - 0.071 12.4 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like 14-3-3 PF00244.20 EAY01333.1 - 3.9e-63 212.9 4.4 4.4e-63 212.8 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 EAY01333.1 - 0.0055 16.8 0.7 2.9 8.3 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAY01333.1 - 0.15 11.8 0.3 0.47 10.2 0.1 1.9 2 0 0 2 2 2 0 TPR repeat TagA PF12561.8 EAY01335.1 - 0.18 12.2 1.9 1 9.8 0.4 3.1 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain Agarase_CBM PF17992.1 EAY01335.1 - 0.18 11.3 6.2 0.41 10.2 0.0 3.7 3 1 0 3 3 3 0 Agarase CBM like domain Drf_FH3 PF06367.16 EAY01336.1 - 0.064 12.9 0.9 0.1 12.2 0.9 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain Spc42p PF11544.8 EAY01336.1 - 2.7 8.0 7.5 13 5.9 0.6 2.7 3 0 0 3 3 3 0 Spindle pole body component Spc42p T5orf172 PF10544.9 EAY01338.1 - 5.2e-07 30.1 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY01338.1 - 0.051 13.4 1.8 0.29 11.0 0.3 2.5 2 2 0 2 2 2 0 KilA-N domain DUF3839 PF12943.7 EAY01339.1 - 4.9e-157 520.6 13.4 6.1e-157 520.3 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Glu-tRNAGln PF02686.15 EAY01339.1 - 0.13 12.5 0.8 0.41 11.0 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2408 PF10303.9 EAY01339.1 - 0.27 11.8 5.1 0.2 12.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAY01339.1 - 3.3 8.2 7.2 6.2 7.4 0.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAY01340.1 - 0.087 13.3 0.6 0.19 12.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY01341.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY01342.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP UQ_con PF00179.26 EAY01343.1 - 1e-16 60.9 1.9 4.3e-16 58.8 0.3 2.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 EAY01343.1 - 5.7e-09 36.6 0.0 1.8e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAY01343.1 - 1.8e-06 28.3 0.0 4.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain U-box PF04564.15 EAY01343.1 - 0.00027 21.1 0.0 0.00068 19.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain Peptidase_M60 PF13402.6 EAY01344.1 - 4.8e-73 246.0 4.8 7.1e-73 245.4 4.8 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 EAY01344.1 - 4e-23 81.4 0.0 9.4e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 EAY01344.1 - 2e-07 30.9 0.2 7.9e-07 29.0 0.2 2.0 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EAY01344.1 - 8.7e-06 26.1 2.7 1.8e-05 25.0 0.4 2.7 2 0 0 2 2 2 1 GLEYA domain Big_9 PF17963.1 EAY01344.1 - 0.0046 17.7 0.9 0.028 15.2 0.0 2.8 3 0 0 3 3 3 1 Bacterial Ig domain fn3 PF00041.21 EAY01344.1 - 0.042 14.2 0.3 30 5.1 0.1 3.2 3 0 0 3 3 3 0 Fibronectin type III domain DNA_pol_A_exo1 PF01612.20 EAY01345.1 - 2.1e-10 40.6 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Snapin_Pallidin PF14712.6 EAY01346.1 - 1.1e-05 25.7 4.1 1.1e-05 25.7 4.1 1.5 1 1 0 1 1 1 1 Snapin/Pallidin Fzo_mitofusin PF04799.13 EAY01346.1 - 0.0011 18.5 2.6 0.0014 18.2 2.6 1.3 1 0 0 1 1 1 1 fzo-like conserved region Lipoprotein_20 PF13942.6 EAY01346.1 - 0.0025 17.7 2.3 0.045 13.7 0.6 2.1 2 0 0 2 2 2 1 YfhG lipoprotein Baculo_PEP_C PF04513.12 EAY01346.1 - 0.0043 17.1 0.1 0.0052 16.8 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 EAY01346.1 - 0.0046 16.1 2.8 0.0048 16.1 2.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Prefoldin PF02996.17 EAY01346.1 - 0.0046 16.9 6.8 0.55 10.2 0.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit TRPM_tetra PF16519.5 EAY01346.1 - 0.0047 17.0 1.8 0.054 13.6 0.1 2.3 2 1 0 2 2 2 1 Tetramerisation domain of TRPM MapZ_EC1 PF18041.1 EAY01346.1 - 0.0069 16.6 1.1 0.013 15.7 1.1 1.5 1 1 0 1 1 1 1 MapZ extracellular domain 1 SCF PF02404.15 EAY01346.1 - 0.0077 15.6 0.7 0.0095 15.3 0.7 1.2 1 0 0 1 1 1 1 Stem cell factor Peptidase_Prp PF04327.12 EAY01346.1 - 0.01 16.0 1.8 0.016 15.5 0.8 1.7 2 0 0 2 2 2 0 Cysteine protease Prp Lipoprotein_6 PF01441.19 EAY01346.1 - 0.022 14.8 3.8 0.91 9.5 0.1 2.0 1 1 1 2 2 2 0 Lipoprotein Tropomyosin_1 PF12718.7 EAY01346.1 - 0.047 13.9 5.9 0.68 10.1 0.4 2.1 1 1 1 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.22 EAY01346.1 - 0.047 13.9 5.1 0.17 12.2 4.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GIT_CC PF16559.5 EAY01346.1 - 0.059 13.3 4.2 2.4 8.1 0.2 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Enkurin PF13864.6 EAY01346.1 - 0.084 13.3 4.0 0.053 14.0 1.6 1.8 1 1 1 2 2 2 0 Calmodulin-binding Allexi_40kDa PF05549.11 EAY01346.1 - 0.09 12.3 1.4 0.1 12.1 1.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein PRD PF00874.20 EAY01346.1 - 0.11 12.8 2.7 0.23 11.8 1.9 1.7 1 1 1 2 2 2 0 PRD domain DUF2205 PF10224.9 EAY01346.1 - 0.13 12.2 3.9 4.6 7.3 1.9 2.6 1 1 2 3 3 3 0 Short coiled-coil protein Matrilin_ccoil PF10393.9 EAY01346.1 - 0.15 12.0 4.5 0.28 11.1 0.7 2.9 2 1 2 4 4 3 0 Trimeric coiled-coil oligomerisation domain of matrilin TMPIT PF07851.13 EAY01346.1 - 0.18 11.0 5.2 0.22 10.8 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein NAD_binding_5 PF07994.12 EAY01346.1 - 0.21 10.9 2.6 0.23 10.8 2.6 1.0 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase WXG100 PF06013.12 EAY01346.1 - 0.23 11.7 3.9 1.9 8.8 0.7 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG XhlA PF10779.9 EAY01346.1 - 0.26 11.5 4.3 8.4 6.7 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 EAY01346.1 - 0.39 10.8 5.3 1.8 8.6 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EAY01347.1 - 0.093 13.3 25.9 0.075 13.6 7.5 2.7 1 1 0 2 2 2 0 Apg6 coiled-coil region ApoA-II PF04711.13 EAY01347.1 - 1.1 9.5 4.7 0.99 9.6 0.1 3.1 3 1 1 4 4 4 0 Apolipoprotein A-II (ApoA-II) PP2C PF00481.21 EAY01348.1 - 4.2e-47 160.9 0.0 5.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAY01348.1 - 2.2e-35 120.2 49.3 1.7e-08 34.1 0.1 9.4 5 3 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 EAY01348.1 - 8.1e-28 96.0 68.4 9.9e-05 22.6 1.9 12.7 8 2 4 13 13 13 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY01348.1 - 1.1e-07 31.6 21.0 0.0013 18.3 1.9 5.0 3 3 1 4 4 4 3 Leucine-rich repeat PP2C_2 PF13672.6 EAY01348.1 - 0.0022 17.7 0.3 0.004 16.8 0.3 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C FNIP PF05725.12 EAY01348.1 - 0.0074 16.4 3.4 0.12 12.5 0.0 4.6 2 1 1 3 3 3 1 FNIP Repeat LRR_6 PF13516.6 EAY01348.1 - 0.0079 16.2 59.2 0.14 12.3 0.9 14.0 17 0 0 17 17 17 4 Leucine Rich repeat LRR_5 PF13306.6 EAY01348.1 - 5.8 6.9 38.9 0.045 13.7 1.7 5.8 4 2 3 7 7 7 0 BspA type Leucine rich repeat region (6 copies) Stig1 PF04885.13 EAY01349.1 - 0.052 14.0 6.0 0.12 12.9 6.0 1.5 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 PetG PF02529.15 EAY01349.1 - 4.6 7.2 5.2 7.6 6.5 5.2 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Filament PF00038.21 EAY01350.1 - 0.0022 17.7 15.1 0.0052 16.4 10.3 2.0 1 1 1 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 EAY01350.1 - 0.0035 17.4 21.2 0.071 13.1 4.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EAY01350.1 - 0.0045 16.1 9.8 0.0051 16.0 9.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 LemA PF04011.12 EAY01350.1 - 0.006 16.5 2.8 0.0078 16.1 1.5 1.6 1 1 1 2 2 2 1 LemA family DUF4239 PF14023.6 EAY01350.1 - 0.25 11.1 5.6 0.45 10.2 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Syntaxin_2 PF14523.6 EAY01350.1 - 0.46 10.9 16.0 1.4 9.4 8.4 2.5 1 1 1 2 2 2 0 Syntaxin-like protein zf-C4H2 PF10146.9 EAY01350.1 - 0.59 10.4 13.1 0.77 10.0 13.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein YabA PF06156.13 EAY01350.1 - 0.92 10.2 15.6 0.3 11.7 3.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA ACCA PF03255.14 EAY01350.1 - 1.6 8.6 10.1 2.1 8.2 5.1 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AKNA PF12443.8 EAY01350.1 - 1.9 9.2 9.9 5.2 7.8 0.7 3.2 1 1 2 3 3 3 0 AT-hook-containing transcription factor APG6_N PF17675.1 EAY01350.1 - 2.2 8.8 18.6 12 6.5 16.5 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 EAY01350.1 - 2.4 8.0 20.3 5.9 6.7 0.4 3.7 2 1 2 4 4 4 0 Septum formation initiator DUF724 PF05266.14 EAY01350.1 - 2.7 7.8 15.1 3.6 7.4 12.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EAY01350.1 - 2.8 8.0 19.5 1.2 9.2 17.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EAY01350.1 - 3.2 8.2 16.7 10 6.6 11.0 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 EAY01350.1 - 3.6 6.8 12.3 1.8 7.7 2.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein Swi5 PF07061.11 EAY01350.1 - 3.6 7.7 16.6 0.48 10.6 1.7 3.7 1 1 2 3 3 3 0 Swi5 Seryl_tRNA_N PF02403.22 EAY01350.1 - 4.1 7.7 16.6 0.95 9.7 11.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.18 EAY01350.1 - 5 7.9 8.0 1.3 9.8 1.2 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TSC22 PF01166.18 EAY01350.1 - 7.2 7.0 11.4 16 5.9 1.0 3.7 2 2 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 EAY01350.1 - 8.2 7.0 19.1 0.12 12.9 2.9 2.9 2 1 1 3 3 3 0 Cell division protein ZapB Ank_2 PF12796.7 EAY01351.1 - 0.00026 21.5 0.0 0.51 11.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY01351.1 - 0.0025 17.7 0.6 0.0084 16.0 0.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY01351.1 - 0.0051 17.2 0.0 26 5.8 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ribosomal_S10 PF00338.22 EAY01351.1 - 0.17 12.1 4.2 0.26 11.5 1.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e Gly-zipper_Omp PF13488.6 EAY01352.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper Zincin_2 PF10103.9 EAY01352.1 - 0.079 12.2 0.0 0.092 12.0 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAY01352.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY01352.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ARA70 PF12489.8 EAY01353.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear coactivator Chal_sti_synt_N PF00195.19 EAY01355.1 - 0.23 10.9 0.4 0.4 10.1 0.4 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF2939 PF11159.8 EAY01356.1 - 0.015 15.7 0.3 0.018 15.5 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Pkinase PF00069.25 EAY01359.1 - 3.6e-68 229.8 0.0 4.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01359.1 - 9.7e-32 110.3 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY01359.1 - 8.4e-06 25.0 0.1 5.4e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAY01359.1 - 0.002 17.5 0.0 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAY01359.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EAY01359.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TcdA_TcdB PF12919.7 EAY01360.1 - 0.014 14.7 0.2 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Ank_4 PF13637.6 EAY01362.1 - 9e-19 67.6 0.7 1.9e-05 25.1 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01362.1 - 4.3e-13 49.1 5.6 0.006 17.0 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAY01362.1 - 4.9e-12 46.3 0.3 6.5e-07 29.8 0.1 2.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01362.1 - 9e-12 45.0 0.0 3.2e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01362.1 - 1.3e-10 40.6 2.8 0.078 13.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat MatE PF01554.18 EAY01363.1 - 7.1e-06 25.8 4.5 7.1e-06 25.8 4.5 3.3 4 0 0 4 4 4 2 MatE Tub PF01167.18 EAY01364.1 - 0.0054 16.5 0.5 0.011 15.6 0.4 1.5 1 1 0 1 1 1 1 Tub family GPS2_interact PF15784.5 EAY01367.1 - 0.097 13.1 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01367.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAY01368.1 - 0.018 15.0 8.3 0.022 14.7 8.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01368.1 - 1.1 9.8 5.3 1.3 9.5 5.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAY01369.1 - 0.042 13.8 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAY01370.1 - 0.016 15.6 0.4 0.021 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) HTH_32 PF13565.6 EAY01370.1 - 3.2 8.4 6.3 7.6 7.2 6.3 1.6 1 1 0 1 1 1 0 Homeodomain-like domain DUF3839 PF12943.7 EAY01371.1 - 1.1e-154 512.8 12.8 1.5e-154 512.5 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY01371.1 - 0.13 12.1 0.8 0.46 10.3 0.2 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY01371.1 - 0.91 10.0 4.7 1.9 9.0 0.6 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pox_A32 PF04665.12 EAY01372.1 - 0.00016 21.2 3.6 0.00016 21.2 3.6 1.8 1 1 1 2 2 2 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY01372.1 - 0.007 16.4 1.2 0.012 15.6 0.2 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAY01372.1 - 0.0081 15.7 0.3 0.018 14.7 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAY01372.1 - 0.041 13.1 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAY01372.1 - 0.074 13.3 2.2 0.18 12.1 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) Apolipoprotein PF01442.18 EAY01373.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TSC22 PF01166.18 EAY01375.1 - 0.00015 22.0 21.5 0.11 12.9 0.4 5.4 4 1 0 4 4 4 2 TSC-22/dip/bun family GIT_CC PF16559.5 EAY01375.1 - 0.0027 17.5 4.4 0.0027 17.5 4.4 4.3 4 1 0 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor Lebercilin PF15619.6 EAY01375.1 - 0.0041 16.8 48.6 0.088 12.5 19.1 4.5 4 1 1 5 5 4 3 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.15 EAY01375.1 - 0.018 15.1 30.2 0.23 11.6 3.1 5.7 5 0 0 5 5 5 0 Basic region leucine zipper YabA PF06156.13 EAY01375.1 - 0.018 15.6 33.5 0.035 14.7 5.2 4.5 3 1 1 4 4 4 0 Initiation control protein YabA FlaC_arch PF05377.11 EAY01375.1 - 0.025 15.0 16.5 0.43 11.0 0.1 5.4 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EAY01375.1 - 0.078 13.1 38.3 0.39 10.8 4.3 6.2 5 3 2 7 7 7 0 bZIP transcription factor GAS PF13851.6 EAY01375.1 - 0.08 12.3 48.4 0.017 14.5 9.9 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 EAY01375.1 - 0.09 13.0 0.6 0.09 13.0 0.6 5.7 5 1 0 5 5 5 0 Homeobox associated leucine zipper DUF4349 PF14257.6 EAY01375.1 - 0.17 11.3 4.3 0.26 10.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Spc24 PF08286.11 EAY01375.1 - 0.3 11.3 34.8 1 9.7 5.2 4.6 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 ZapB PF06005.12 EAY01375.1 - 0.31 11.5 47.1 0.056 13.9 2.7 5.4 3 2 0 4 4 4 0 Cell division protein ZapB Cnn_1N PF07989.11 EAY01375.1 - 0.34 11.1 45.2 10 6.3 4.0 5.9 1 1 2 3 3 2 0 Centrosomin N-terminal motif 1 HAP1_N PF04849.13 EAY01375.1 - 0.44 9.7 42.6 0.12 11.6 19.2 3.5 1 1 3 4 4 4 0 HAP1 N-terminal conserved region DUF948 PF06103.11 EAY01375.1 - 0.72 10.2 9.3 14 6.0 0.2 4.6 4 1 1 5 5 4 0 Bacterial protein of unknown function (DUF948) Herpes_BLRF2 PF05812.12 EAY01375.1 - 0.79 9.9 27.7 0.47 10.6 0.3 4.7 4 1 0 5 5 5 0 Herpesvirus BLRF2 protein Shugoshin_N PF07558.11 EAY01375.1 - 0.81 9.6 22.6 0.16 11.8 1.3 5.1 5 0 0 5 5 4 0 Shugoshin N-terminal coiled-coil region DASH_Hsk3 PF08227.11 EAY01375.1 - 1.7 9.1 8.6 18 5.8 0.5 3.8 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Speriolin_N PF15058.6 EAY01375.1 - 2.9 7.9 8.7 4.7 7.3 0.2 2.6 3 0 0 3 3 3 0 Speriolin N terminus NYD-SP28_assoc PF14775.6 EAY01375.1 - 3.4 7.8 19.9 1.1 9.4 1.1 4.6 4 1 0 4 4 4 0 Sperm tail C-terminal domain Leu_zip PF15294.6 EAY01375.1 - 3.8 6.9 39.4 1 8.8 9.3 2.6 1 1 1 2 2 2 0 Leucine zipper PRKG1_interact PF15898.5 EAY01375.1 - 4 8.4 42.2 3.2 8.7 9.4 4.1 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain GOLGA2L5 PF15070.6 EAY01375.1 - 4.9 5.7 39.4 4.6 5.8 24.3 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Filament PF00038.21 EAY01375.1 - 5.3 6.5 39.3 0.082 12.5 6.7 3.3 1 1 2 3 3 3 0 Intermediate filament protein ERM PF00769.19 EAY01375.1 - 5.9 6.6 40.4 13 5.6 19.7 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Ax_dynein_light PF10211.9 EAY01375.1 - 6.9 6.6 43.4 3.8 7.4 7.7 4.0 3 1 0 4 4 4 0 Axonemal dynein light chain FPP PF05911.11 EAY01375.1 - 7.5 4.6 44.1 13 3.8 24.8 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Ribosomal_L24e PF01246.20 EAY01376.1 - 2.3e-22 79.0 1.5 2.3e-22 79.0 1.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e RRM_1 PF00076.22 EAY01377.1 - 1.4e-14 53.7 0.0 2.7e-14 52.7 0.0 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAY01377.1 - 0.0026 18.0 0.0 0.16 12.2 0.0 2.2 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Phage_min_cap2 PF06152.11 EAY01377.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.5 1 1 0 1 1 1 0 Phage minor capsid protein 2 Ribosomal_S13_N PF08069.12 EAY01378.1 - 1.6e-25 88.9 0.0 2.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EAY01378.1 - 6.2e-13 48.8 1.6 8.5e-13 48.3 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ras PF00071.22 EAY01379.1 - 6.7e-44 149.3 0.2 7.8e-44 149.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01379.1 - 3.3e-29 101.5 0.0 5.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01379.1 - 4.6e-13 49.0 0.0 6.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAY01379.1 - 2.4e-07 30.8 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAY01379.1 - 6.3e-05 23.0 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAY01379.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 EAY01379.1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EAY01379.1 - 0.038 14.5 0.1 0.11 13.0 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EAY01379.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAY01379.1 - 0.053 13.3 0.2 0.66 9.7 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAY01379.1 - 0.07 12.7 0.1 1.1 8.8 0.0 2.3 2 2 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 EAY01379.1 - 0.11 12.8 0.0 0.85 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 EAY01380.1 - 2.2e-41 136.6 25.0 0.00012 21.9 0.0 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.6 EAY01380.1 - 2.9e-27 92.6 21.8 0.0024 18.0 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EAY01380.1 - 3.5e-25 86.7 32.2 0.00022 20.9 0.0 10.4 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAY01380.1 - 6.1e-24 84.3 22.4 5.1e-06 26.9 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAY01380.1 - 1e-22 80.2 18.3 0.00068 19.9 1.4 7.6 4 3 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 EAY01380.1 - 1.3e-22 80.2 5.4 7.1e-06 26.6 0.0 7.0 5 1 2 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EAY01380.1 - 2.2e-20 72.1 22.1 0.0042 16.7 0.0 10.1 6 3 5 11 11 11 6 TPR repeat TPR_6 PF13174.6 EAY01380.1 - 1.6e-19 69.2 18.9 0.016 15.8 0.0 11.1 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAY01380.1 - 3.5e-19 67.8 14.3 0.017 15.9 0.0 10.4 5 3 6 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAY01380.1 - 1.4e-15 56.1 16.1 0.099 12.7 0.2 9.9 10 1 0 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EAY01380.1 - 7.2e-13 48.6 22.5 1.8e-05 24.9 0.2 6.4 3 2 5 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EAY01380.1 - 1e-12 47.5 20.9 0.39 11.2 0.4 9.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EAY01380.1 - 1.9e-11 44.0 0.6 0.027 14.6 0.0 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAY01380.1 - 3.7e-08 32.9 13.8 6.7e-06 25.5 0.6 5.1 2 1 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 EAY01380.1 - 8.1e-05 22.4 20.6 0.0016 18.2 5.6 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 EAY01380.1 - 0.00032 20.7 16.9 0.72 10.0 1.1 7.0 7 1 1 8 8 6 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 EAY01380.1 - 0.0011 18.1 2.7 0.021 13.8 0.1 2.6 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EAY01380.1 - 0.0017 18.2 20.3 0.56 10.2 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EAY01380.1 - 0.0024 17.9 8.5 3.4 7.7 0.0 5.7 4 2 2 6 6 5 1 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 EAY01380.1 - 0.0043 16.5 12.9 0.44 9.9 0.4 4.5 4 1 0 4 4 4 2 Coatomer epsilon subunit DUF3808 PF10300.9 EAY01380.1 - 0.0044 15.8 0.2 0.0044 15.8 0.2 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF3808) SHNi-TPR PF10516.9 EAY01380.1 - 0.022 14.2 0.1 0.57 9.7 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR PPR PF01535.20 EAY01380.1 - 0.04 14.2 1.0 23 5.5 0.1 4.7 6 0 0 6 6 3 0 PPR repeat BTAD PF03704.17 EAY01380.1 - 0.05 14.0 10.6 6.8 7.1 1.7 5.2 3 3 2 5 5 5 0 Bacterial transcriptional activator domain Metal_resist PF13801.6 EAY01380.1 - 0.06 13.5 0.7 0.68 10.1 0.2 2.5 2 0 0 2 2 2 0 Heavy-metal resistance NRDE-2 PF08424.10 EAY01380.1 - 0.11 11.6 3.3 0.24 10.5 1.4 2.1 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference PCI PF01399.27 EAY01380.1 - 0.27 11.8 1.7 0.77 10.3 0.8 2.2 2 0 0 2 2 1 0 PCI domain Methyltransf_25 PF13649.6 EAY01380.1 - 0.27 11.9 0.7 32 5.3 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain Sel1 PF08238.12 EAY01380.1 - 1.8 9.3 8.9 13 6.7 0.2 5.1 5 0 0 5 5 4 0 Sel1 repeat Spore_II_R PF09551.10 EAY01380.1 - 2.2 8.8 5.4 3.5 8.1 1.3 2.7 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) MIT PF04212.18 EAY01380.1 - 9.8 6.3 21.5 1.7 8.8 0.1 7.0 6 2 2 8 8 6 0 MIT (microtubule interacting and transport) domain Chlam_PMP PF02415.17 EAY01381.1 - 1.7 9.3 14.8 2.4 8.8 0.1 5.9 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LRR_5 PF13306.6 EAY01383.1 - 2.4e-100 331.4 74.6 5e-26 91.2 10.5 7.3 2 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01383.1 - 1.4e-19 69.6 1.7 0.0017 18.1 0.0 9.0 7 2 4 11 11 10 4 Leucine rich repeat LRR_4 PF12799.7 EAY01383.1 - 5.5e-07 29.8 3.6 0.63 10.5 0.0 6.8 8 0 0 8 8 8 2 Leucine Rich repeats (2 copies) ATP-synt_ab PF00006.25 EAY01384.1 - 3.7e-64 216.3 0.0 5.5e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAY01384.1 - 1.1e-11 45.1 0.7 1.8e-11 44.3 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EAY01384.1 - 0.075 13.2 0.7 0.21 11.8 0.7 1.8 1 0 0 1 1 1 0 HAS barrel domain NLPC_P60 PF00877.19 EAY01385.1 - 1.7e-19 69.8 0.0 3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 EAY01385.1 - 4.2e-05 23.5 0.1 0.00048 20.1 0.1 2.4 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase Phage_GP20 PF06810.11 EAY01386.1 - 0.0015 18.3 14.0 0.0015 18.3 14.0 10.3 3 2 5 9 9 9 1 Phage minor structural protein GP20 Spc7 PF08317.11 EAY01386.1 - 0.1 11.5 178.5 0.03 13.2 24.8 7.5 3 3 5 8 8 8 0 Spc7 kinetochore protein FUSC PF04632.12 EAY01386.1 - 3.1 6.2 38.0 0.24 9.9 0.1 4.9 3 2 2 5 5 5 0 Fusaric acid resistance protein family HMG_box PF00505.19 EAY01387.1 - 1.7e-23 82.8 0.9 1.7e-23 82.8 0.9 1.8 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAY01387.1 - 1.3e-14 54.5 0.5 1.3e-14 54.5 0.5 1.8 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 EAY01387.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF1043 PF06295.12 EAY01387.1 - 0.14 12.2 4.2 0.18 11.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RR_TM4-6 PF06459.12 EAY01387.1 - 0.73 9.6 11.7 0.79 9.5 11.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 EAY01387.1 - 0.91 9.8 14.5 0.99 9.7 14.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YABBY PF04690.13 EAY01387.1 - 3.2 8.3 6.9 4.3 7.9 0.0 2.0 1 1 1 2 2 2 0 YABBY protein Peptidase_S49_N PF08496.10 EAY01387.1 - 4.7 7.2 9.4 5.3 7.1 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 EAY01387.1 - 7 6.3 6.6 8.2 6.1 6.6 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EAY01387.1 - 9.2 4.9 6.1 8.5 5.0 6.1 1.0 1 0 0 1 1 1 0 Presenilin Calreticulin PF00262.18 EAY01388.1 - 4.9e-34 117.8 20.9 1.3e-33 116.4 20.9 1.7 1 1 0 1 1 1 1 Calreticulin family Ndr PF03096.14 EAY01388.1 - 0.089 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family OCC1 PF15506.6 EAY01388.1 - 0.38 10.9 2.6 0.79 9.9 2.6 1.4 1 0 0 1 1 1 0 OCC1 family C9orf72-like PF15019.6 EAY01389.1 - 5.4e-61 206.3 8.4 1.2e-60 205.1 4.7 2.0 2 0 0 2 2 2 2 C9orf72-like protein family tRNA_NucTran2_2 PF13735.6 EAY01389.1 - 0.0014 18.7 0.1 0.0034 17.4 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Peptidase_C1 PF00112.23 EAY01390.1 - 7.3e-62 209.3 3.5 9.1e-62 209.0 3.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAY01390.1 - 9.9e-09 35.5 1.3 1.6e-08 34.9 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAY01390.1 - 0.00048 19.0 1.4 0.16 10.8 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family CREPT PF16566.5 EAY01391.1 - 0.0043 17.2 3.2 0.011 15.9 0.3 2.1 1 1 1 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour HAUS6_N PF14661.6 EAY01391.1 - 0.007 16.0 0.4 0.0082 15.7 0.4 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Adeno_E4 PF05385.11 EAY01391.1 - 0.091 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein HMMR_N PF15905.5 EAY01391.1 - 0.11 11.9 6.1 0.13 11.7 6.1 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal KicB PF03882.14 EAY01392.1 - 0.014 15.6 0.5 0.034 14.3 0.5 1.7 1 0 0 1 1 1 0 MukF winged-helix domain TetR_C_8 PF14278.6 EAY01392.1 - 0.033 14.3 9.5 0.073 13.2 1.8 3.7 3 2 0 3 3 3 0 Transcriptional regulator C-terminal region DUF4789 PF16033.5 EAY01392.1 - 0.036 14.6 0.3 0.071 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4789) SGTA_dimer PF16546.5 EAY01392.1 - 2.3 8.1 5.9 28 4.6 0.4 3.6 3 1 0 3 3 3 0 Homodimerisation domain of SGTA Sulfatase PF00884.23 EAY01393.1 - 4.3e-16 59.2 0.4 6.9e-16 58.5 0.4 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EAY01393.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Clr5 PF14420.6 EAY01393.1 - 0.087 13.1 1.1 0.17 12.1 0.2 1.9 1 1 1 2 2 2 0 Clr5 domain Lactamase_B PF00753.27 EAY01394.1 - 3.4e-17 63.1 2.3 4.7e-17 62.7 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAY01394.1 - 9.8e-05 21.9 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA_lid_7 PF17867.1 EAY01394.1 - 0.037 14.2 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Midasin AAA lid domain P_proprotein PF01483.20 EAY01395.1 - 4.1e-13 49.2 0.0 7.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain TMEM154 PF15102.6 EAY01395.1 - 0.00084 19.3 1.1 0.003 17.5 1.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EAY01395.1 - 0.005 16.9 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 EAY01395.1 - 0.02 15.2 0.2 0.074 13.3 0.2 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Orf78 PF06024.12 EAY01395.1 - 0.028 14.7 0.1 0.085 13.2 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 EAY01395.1 - 0.035 14.4 0.2 0.099 12.9 0.2 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Meiosis_expr PF15163.6 EAY01396.1 - 0.024 15.3 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed ST7 PF04184.12 EAY01396.1 - 0.12 10.9 0.2 0.12 10.9 0.2 1.0 1 0 0 1 1 1 0 ST7 protein PHP_C PF13263.6 EAY01396.1 - 0.16 11.7 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAY01396.1 - 9.5 6.2 12.4 0.14 12.0 2.8 2.9 4 1 0 4 4 4 0 Spo12 family DUF4795 PF16043.5 EAY01397.1 - 0.11 12.1 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_fiber PF03335.13 EAY01397.1 - 0.78 10.1 12.3 4.4 7.7 3.3 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF1947 PF09183.10 EAY01397.1 - 4.1 7.8 5.5 5.8 7.3 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) DUF4107 PF13389.6 EAY01400.1 - 4.4e-72 241.5 3.1 6.1e-72 241.1 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) IBN_N PF03810.19 EAY01401.1 - 3.3e-06 26.9 1.2 1.3e-05 25.0 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EAY01401.1 - 0.00068 19.7 19.2 0.0014 18.7 6.1 3.6 3 1 1 4 4 4 2 Exportin 1-like protein DUF4158 PF13700.6 EAY01401.1 - 0.0065 16.3 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) DUF3447 PF11929.8 EAY01402.1 - 1.7e-20 72.7 3.7 1.7e-20 72.7 3.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01402.1 - 9.5e-10 38.9 3.4 2.7e-07 31.1 3.4 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01402.1 - 5.6e-06 26.8 2.2 0.15 12.7 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01402.1 - 6.1e-06 26.4 1.4 0.00011 22.4 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01402.1 - 0.00042 20.5 4.2 2 9.2 0.1 4.2 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAY01402.1 - 0.00067 20.0 0.1 1.3 9.6 0.1 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAY01403.1 - 5.3e-30 103.8 8.0 1.2e-13 51.4 1.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01403.1 - 3.7e-27 94.3 0.2 3.3e-12 46.6 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01403.1 - 1.4e-18 65.0 3.9 7e-05 22.9 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAY01403.1 - 2.3e-18 65.8 0.6 3.3e-06 27.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAY01403.1 - 1.2e-16 60.5 3.8 1.9e-06 28.0 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01404.1 - 1.6e-08 35.0 0.0 6.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01404.1 - 3.6e-08 33.0 0.0 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAY01404.1 - 4.3e-08 33.2 0.0 2.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAY01404.1 - 9.1e-08 32.5 0.0 9.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01404.1 - 4.4e-07 30.1 0.0 6.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01405.1 - 3e-18 66.2 0.3 1e-15 58.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01405.1 - 3.5e-13 49.5 0.1 8.8e-10 38.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01405.1 - 2.2e-12 46.0 0.0 0.00018 21.7 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAY01405.1 - 5.8e-12 45.9 0.1 2.3e-06 28.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01405.1 - 3.1e-06 27.4 0.0 0.0004 20.7 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 EAY01406.1 - 3.8e-06 27.4 0.0 0.00039 21.0 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01406.1 - 0.00096 19.4 0.0 3 8.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 EAY01406.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 3.4 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY01406.1 - 0.038 14.6 0.1 5 7.8 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) KAP PF05804.12 EAY01407.1 - 1.8e-40 138.8 10.6 1.9e-38 132.2 10.6 2.0 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) DUF4441 PF14536.6 EAY01407.1 - 8.6 6.6 9.5 0.29 11.3 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) RhoGEF PF00621.20 EAY01408.1 - 7.1e-29 101.3 1.0 1.8e-28 100.0 1.0 1.7 1 0 0 1 1 1 1 RhoGEF domain Kelch_6 PF13964.6 EAY01408.1 - 4.2e-12 45.9 4.2 2.2e-06 27.7 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EAY01408.1 - 9.9e-12 44.8 1.0 5.5e-06 26.5 0.1 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EAY01408.1 - 2e-11 43.7 3.7 2.5e-07 30.6 0.1 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EAY01408.1 - 3.2e-11 42.9 0.2 0.0019 18.1 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EAY01408.1 - 2.5e-09 36.7 1.0 0.0054 16.7 0.1 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EAY01408.1 - 2.1e-08 33.6 9.0 4.3e-07 29.4 0.1 3.5 4 0 0 4 4 4 2 Kelch motif F5_F8_type_C PF00754.25 EAY01409.1 - 4.3e-07 30.1 0.1 2.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 F5/8 type C domain Ank PF00023.30 EAY01410.1 - 1e-80 262.9 27.8 2.1e-07 31.1 0.3 13.1 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.7 EAY01410.1 - 7.1e-79 260.5 30.2 2e-15 57.1 0.7 7.1 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01410.1 - 6.1e-74 243.5 14.5 2.8e-12 46.9 0.1 11.0 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01410.1 - 8.8e-67 213.1 18.8 9.4e-07 28.7 0.1 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 EAY01410.1 - 3.1e-66 218.6 16.6 5.7e-12 45.6 0.3 7.5 4 1 3 8 8 8 8 Ankyrin repeats (many copies) MetallophosN PF16371.5 EAY01410.1 - 2.4e-05 24.5 0.0 1.2 9.5 0.0 5.3 4 1 2 6 6 6 1 N terminal of Calcineurin-like phosphoesterase Peptidase_M16 PF00675.20 EAY01410.1 - 5.8e-05 23.1 3.2 8.3 6.4 0.0 6.0 3 2 5 8 8 8 1 Insulinase (Peptidase family M16) DUF249 PF03158.13 EAY01410.1 - 0.0034 17.1 5.1 0.5 10.1 0.2 4.1 1 1 2 4 4 4 3 Multigene family 530 protein HEM4 PF02602.15 EAY01410.1 - 0.06 12.7 0.1 13 5.0 0.0 3.0 3 1 0 3 3 3 0 Uroporphyrinogen-III synthase HemD HeH PF12949.7 EAY01410.1 - 6.2 6.6 6.0 16 5.3 0.1 4.1 5 0 0 5 5 5 0 HeH/LEM domain NADH-UOR_E PF16514.5 EAY01411.1 - 0.25 11.7 6.1 0.69 10.3 0.3 4.1 3 0 0 3 3 3 0 putative NADH-ubiquinone oxidoreductase chain E TatD_DNase PF01026.21 EAY01412.1 - 7.3e-61 205.8 0.0 8.3e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EAY01412.1 - 0.0007 19.5 0.2 0.0089 15.8 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase CK_II_beta PF01214.18 EAY01413.1 - 5.4e-55 186.0 0.1 6.9e-55 185.7 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit UDPG_MGDP_dh_N PF03721.14 EAY01414.1 - 1.7e-29 102.8 0.0 3.7e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EAY01414.1 - 2.6e-23 82.0 0.0 5.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 EAY01414.1 - 0.012 15.5 0.0 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EAY01414.1 - 0.019 14.9 0.0 0.085 12.8 0.0 2.0 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EAY01414.1 - 0.056 12.8 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EAY01414.1 - 0.096 13.1 0.0 7.7 7.0 0.0 3.1 2 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Ank_2 PF12796.7 EAY01415.1 - 3.1e-53 178.3 34.8 2.1e-17 63.5 0.7 6.1 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01415.1 - 4.3e-42 141.9 18.4 9.3e-13 48.4 0.0 9.4 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAY01415.1 - 8.5e-41 136.7 11.2 1.8e-05 25.0 1.3 8.5 8 0 0 8 8 8 6 Ankyrin repeat DUF3447 PF11929.8 EAY01415.1 - 6e-37 125.5 8.5 6e-37 125.5 8.5 5.1 3 2 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY01415.1 - 1.4e-34 114.2 17.5 7.9e-05 22.8 0.0 9.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAY01415.1 - 1.8e-26 91.9 18.4 1.5e-08 34.7 1.9 7.4 5 3 4 9 9 9 5 Ankyrin repeats (many copies) RL PF17797.1 EAY01415.1 - 2.7 8.0 7.1 24 5.0 0.5 4.8 4 1 1 6 6 6 0 RL domain ubiquitin PF00240.23 EAY01416.1 - 0.028 14.2 0.3 0.028 14.2 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin family UBA PF00627.31 EAY01416.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain SCAMP PF04144.13 EAY01417.1 - 7.3e-25 88.3 11.1 9e-25 88.0 11.1 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 EAY01417.1 - 0.025 14.0 1.1 0.045 13.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1090 PF06476.12 EAY01417.1 - 0.03 14.4 2.4 0.048 13.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF2207 PF09972.9 EAY01417.1 - 0.64 8.7 11.0 2.7 6.6 0.1 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FeoB_associated PF12669.7 EAY01417.1 - 0.78 10.2 2.6 13 6.2 0.2 2.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein RseC_MucC PF04246.12 EAY01417.1 - 1.7 8.6 9.5 0.34 10.9 4.3 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4293 PF14126.6 EAY01417.1 - 1.9 8.7 5.2 0.36 11.1 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) TALPID3 PF15324.6 EAY01417.1 - 3 5.4 10.8 4.3 4.9 10.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target RabGAP-TBC PF00566.18 EAY01418.1 - 3.5e-24 85.7 8.6 1.1e-23 84.0 8.6 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Clathrin_lg_ch PF01086.17 EAY01419.1 - 0.00018 21.6 14.0 0.0002 21.5 14.0 1.1 1 0 0 1 1 1 1 Clathrin light chain DUF737 PF05300.11 EAY01419.1 - 0.068 13.5 11.3 0.088 13.2 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PA26 PF04636.13 EAY01419.1 - 0.084 11.8 6.0 0.096 11.6 6.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cdh1_DBD_1 PF18196.1 EAY01419.1 - 1.1 9.6 12.5 2.6 8.4 10.8 2.0 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 RAP1 PF07218.11 EAY01419.1 - 2.8 6.1 10.5 3 6.0 10.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HSBP1 PF06825.12 EAY01420.1 - 0.11 12.3 5.1 0.27 11.1 0.4 3.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF1664 PF07889.12 EAY01420.1 - 0.69 10.0 26.6 1.4 9.0 9.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) 5_nucleotid PF05761.14 EAY01420.1 - 0.76 8.6 18.9 1.2 8.0 3.7 2.3 2 0 0 2 2 2 0 5' nucleotidase family CSN5_C PF18323.1 EAY01420.1 - 1.4 9.9 21.9 9.6 7.2 1.8 3.4 1 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain WD40 PF00400.32 EAY01421.1 - 3.6e-19 68.8 1.9 1.5e-05 25.6 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY01421.1 - 4e-07 30.2 0.0 0.016 15.5 0.0 3.7 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Katanin_con80 PF13925.6 EAY01421.1 - 1.4e-06 28.5 0.1 2.6e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 con80 domain of Katanin WD40_like PF17005.5 EAY01421.1 - 0.0048 16.3 0.1 1.1 8.5 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Frtz PF11768.8 EAY01421.1 - 0.0081 14.5 0.0 0.12 10.7 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Proton_antipo_C PF01010.19 EAY01421.1 - 0.11 12.1 0.9 6.4 6.3 0.1 2.8 3 0 0 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus PSP PF04046.16 EAY01423.1 - 0.22 11.4 1.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY01424.1 - 0.06 13.9 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY01425.1 - 0.02 15.4 0.6 0.043 14.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) PTR PF12789.7 EAY01426.1 - 5.1e-62 205.8 45.7 1.7e-32 111.3 17.2 7.1 6 3 3 9 9 8 3 Phage tail repeat like DUF3391 PF11871.8 EAY01426.1 - 0.083 13.4 4.3 0.7 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PH_TFIIH PF08567.11 EAY01426.1 - 4.3 7.7 6.4 29 5.1 0.2 4.0 1 1 4 5 5 5 0 TFIIH p62 subunit, N-terminal domain DUF3839 PF12943.7 EAY01427.1 - 6.5e-159 526.8 14.0 8e-159 526.5 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY01427.1 - 3 8.4 7.5 2.1 8.8 0.4 3.4 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAY01428.1 - 7.8e-23 80.5 0.6 1.8e-22 79.3 0.0 1.9 2 1 0 2 2 2 1 KilA-N domain KilA-N PF04383.13 EAY01429.1 - 3.1e-42 142.9 0.1 5.8e-42 142.1 0.1 1.4 1 0 0 1 1 1 1 KilA-N domain DUF3213 PF11491.8 EAY01429.1 - 0.0034 17.5 0.1 0.0066 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) RRP36 PF06102.12 EAY01429.1 - 0.022 14.7 0.3 0.022 14.7 0.3 1.6 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 MPS2 PF17060.5 EAY01429.1 - 0.054 12.8 3.1 1.8 7.7 1.0 2.0 1 1 0 2 2 2 0 Monopolar spindle protein 2 Cep57_MT_bd PF06657.13 EAY01429.1 - 0.077 13.5 4.7 0.27 11.7 2.9 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FPN1 PF06963.12 EAY01429.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4810 PF16068.5 EAY01429.1 - 0.088 13.4 0.1 15 6.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) KilA-N PF04383.13 EAY01430.1 - 0.0064 16.3 1.3 0.022 14.6 1.3 1.9 1 1 0 1 1 1 1 KilA-N domain T5orf172 PF10544.9 EAY01430.1 - 0.051 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 T5orf172 domain HMMR_N PF15905.5 EAY01432.1 - 0.00039 20.0 15.2 0.00039 20.0 15.2 7.6 5 2 2 7 7 7 2 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 EAY01432.1 - 0.00051 20.3 21.6 0.00051 20.3 21.6 10.0 4 2 5 10 10 10 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 EAY01432.1 - 0.0013 17.7 152.1 0.016 14.1 17.7 7.1 3 3 3 6 6 6 5 Spc7 kinetochore protein DUF4164 PF13747.6 EAY01432.1 - 0.014 15.6 6.7 0.014 15.6 6.7 10.8 6 5 6 12 12 12 0 Domain of unknown function (DUF4164) Glu-tRNAGln PF02686.15 EAY01432.1 - 7.3 7.0 10.5 1.2 9.5 0.2 4.6 5 0 0 5 5 5 0 Glu-tRNAGln amidotransferase C subunit Ribosomal_S14 PF00253.21 EAY01433.1 - 1.9e-14 53.2 5.2 2.1e-14 53.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS91 PF14319.6 EAY01433.1 - 0.034 14.2 1.0 0.037 14.1 1.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_2 PF13696.6 EAY01433.1 - 2.2 8.2 7.5 8.4 6.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle XPG_I PF00867.18 EAY01434.1 - 8.9e-05 22.8 0.0 0.00034 20.9 0.0 2.1 1 0 0 1 1 1 1 XPG I-region CRM1_C PF08767.11 EAY01435.1 - 7.1e-10 38.6 8.3 1e-09 38.0 3.5 2.9 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EAY01435.1 - 4e-06 27.0 8.0 4.6e-06 26.8 0.1 4.1 5 0 0 5 5 5 1 Exportin 1-like protein DUF4020 PF13212.6 EAY01435.1 - 0.028 14.3 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) CRM1_repeat_2 PF18784.1 EAY01435.1 - 0.11 12.2 0.1 0.63 9.7 0.1 2.4 1 1 0 1 1 1 0 CRM1 / Exportin repeat 2 Ribosomal_L5e PF17144.4 EAY01436.1 - 3.6e-70 235.2 1.3 7.3e-70 234.2 1.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EAY01436.1 - 1.3e-24 86.9 9.6 1.3e-24 86.9 9.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF2853 PF11015.8 EAY01436.1 - 0.071 13.8 0.7 0.071 13.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Thr_synth_N PF14821.6 EAY01436.1 - 0.09 13.0 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus DUF4604 PF15377.6 EAY01436.1 - 2 8.8 10.1 3.8 7.9 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Sec8_exocyst PF04048.14 EAY01437.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain VPS9 PF02204.18 EAY01438.1 - 0.024 14.8 2.3 0.037 14.2 0.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain MitMem_reg PF13012.6 EAY01438.1 - 2.5 8.6 5.7 35 4.9 0.6 3.5 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function DUF4108 PF13390.6 EAY01442.1 - 5.4e-61 204.7 4.8 6e-61 204.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) DUF2897 PF11446.8 EAY01443.1 - 2 8.4 3.7 3.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PTR PF12789.7 EAY01444.1 - 6e-26 90.3 28.1 4.7e-24 84.2 11.5 5.0 4 1 0 4 4 4 3 Phage tail repeat like Phage_fiber PF03335.13 EAY01444.1 - 3.8 7.9 36.2 6 7.3 0.3 6.6 6 0 0 6 6 6 0 Phage tail fibre repeat TMP PF05017.14 EAY01445.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY01446.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAY01448.1 - 9.5e-08 32.5 0.0 0.0009 19.8 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01448.1 - 0.00011 22.3 0.5 1.4 9.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat APOBEC4_like PF18774.1 EAY01448.1 - 0.00038 20.4 0.4 0.00091 19.2 0.2 1.7 2 0 0 2 2 2 1 APOBEC4-like -AID/APOBEC-deaminase DUF3447 PF11929.8 EAY01448.1 - 0.00092 19.1 0.6 0.00092 19.1 0.6 3.2 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) APOBEC1 PF18769.1 EAY01448.1 - 0.0015 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 APOBEC1 Ank_4 PF13637.6 EAY01448.1 - 0.0053 17.3 0.1 2 9.1 0.0 4.1 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY01448.1 - 0.0084 16.5 0.0 2.3 8.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Pallilysin PF18663.1 EAY01449.1 - 0.096 12.7 0.6 0.27 11.2 0.6 1.7 1 0 0 1 1 1 0 Pallilysin beta barrel domain DUF3208 PF11482.8 EAY01450.1 - 0.077 13.3 0.2 2.5 8.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3208) Carbpep_Y_N PF05388.11 EAY01450.1 - 1.2 9.6 6.6 20 5.8 0.1 3.9 2 1 1 4 4 4 0 Carboxypeptidase Y pro-peptide DUF505 PF04458.12 EAY01451.1 - 0.67 8.3 1.7 0.82 8.0 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) COMM_domain PF07258.14 EAY01452.1 - 4.4e-05 23.5 0.1 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 COMM domain DUF1952 PF09189.10 EAY01453.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) G-alpha PF00503.20 EAY01455.1 - 3.8e-89 299.3 3.0 4.5e-89 299.1 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAY01455.1 - 5.5e-10 39.0 0.2 1.5e-07 31.0 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY01455.1 - 0.0011 18.3 1.2 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EAY01455.1 - 0.0022 18.2 0.2 0.75 10.0 0.1 2.5 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EAY01455.1 - 0.088 13.4 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain MliC PF09864.9 EAY01456.1 - 0.12 12.3 0.1 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DDE_1 PF03184.19 EAY01457.1 - 2e-16 60.1 0.0 3.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GPS2_interact PF15784.5 EAY01459.1 - 0.046 14.2 0.4 0.055 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01459.1 - 0.13 11.3 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAY01460.1 - 0.044 13.8 7.2 0.069 13.1 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01460.1 - 1.8 9.0 5.7 2.6 8.5 5.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2939 PF11159.8 EAY01462.1 - 0.018 15.4 0.6 0.027 14.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY01462.1 - 2.5 8.1 5.9 2.7 8.0 5.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2400 PF09674.10 EAY01463.1 - 0.078 13.0 0.4 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DNA_pol_B_2 PF03175.13 EAY01464.1 - 6.2e-09 35.2 1.0 1.2e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAY01464.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAY01464.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF4108 PF13390.6 EAY01465.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) TK PF00265.18 EAY01466.1 - 5.6e-74 247.8 0.1 2.1e-50 171.0 0.0 3.0 2 1 0 2 2 2 2 Thymidine kinase AAA_14 PF13173.6 EAY01466.1 - 1.1e-05 25.5 0.0 0.088 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EAY01466.1 - 0.0018 18.2 0.0 0.47 10.3 0.0 2.4 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea RecA PF00154.21 EAY01466.1 - 0.11 12.0 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Spc7 PF08317.11 EAY01467.1 - 0.0044 15.9 2.4 0.0059 15.5 2.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FapA PF03961.13 EAY01467.1 - 0.0071 15.0 1.3 0.01 14.5 1.3 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Nucleopor_Nup85 PF07575.13 EAY01467.1 - 0.017 13.7 0.3 0.021 13.4 0.3 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF713 PF05218.14 EAY01467.1 - 0.018 14.8 5.0 0.068 12.9 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF713) EzrA PF06160.12 EAY01467.1 - 0.043 12.0 6.7 0.024 12.8 4.7 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Lectin_N PF03954.14 EAY01467.1 - 0.048 13.4 2.5 0.091 12.5 0.9 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain RICH PF05062.12 EAY01467.1 - 0.057 13.8 0.7 0.057 13.8 0.7 2.0 2 1 0 2 2 2 0 RICH domain Baculo_PEP_C PF04513.12 EAY01467.1 - 0.084 12.9 1.2 0.6 10.2 1.4 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBCC_N PF16752.5 EAY01467.1 - 0.11 13.0 2.8 0.43 11.0 2.5 2.0 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF4706 PF15797.5 EAY01467.1 - 0.12 12.9 1.0 0.69 10.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) FlxA PF14282.6 EAY01467.1 - 0.18 11.8 6.3 0.12 12.4 1.2 2.6 2 1 1 3 3 3 0 FlxA-like protein Laminin_II PF06009.12 EAY01467.1 - 0.19 11.7 1.0 0.4 10.7 0.4 1.8 2 1 0 2 2 2 0 Laminin Domain II DUF1640 PF07798.11 EAY01467.1 - 0.22 11.5 2.3 0.66 10.0 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cytochrom_B562 PF07361.11 EAY01467.1 - 0.34 11.6 2.9 1.1 10.0 2.2 2.1 2 1 0 2 2 2 0 Cytochrome b562 SF-assemblin PF06705.11 EAY01467.1 - 0.37 10.1 4.1 0.56 9.5 4.1 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin TPR_MLP1_2 PF07926.12 EAY01467.1 - 0.75 9.9 5.6 0.49 10.5 0.9 2.3 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 EAY01467.1 - 0.95 9.7 4.9 2.9 8.2 4.9 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DMPK_coil PF08826.10 EAY01467.1 - 1.8 8.7 4.6 1.1 9.4 0.7 2.4 3 0 0 3 3 3 0 DMPK coiled coil domain like Tropomyosin_1 PF12718.7 EAY01467.1 - 2.1 8.5 7.5 21 5.2 1.7 2.9 2 1 1 3 3 3 0 Tropomyosin like HSCB_C PF07743.13 EAY01467.1 - 3.3 8.3 7.3 1.3 9.6 2.5 2.3 2 1 1 3 3 2 0 HSCB C-terminal oligomerisation domain Vps26 PF03643.15 EAY01468.1 - 2.7e-32 111.9 0.0 3.6e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Guanylate_kin PF00625.21 EAY01469.1 - 9.5e-56 188.3 0.2 1.1e-55 188.2 0.2 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 EAY01469.1 - 6.4e-06 26.2 0.0 2.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EAY01469.1 - 2.7e-05 24.7 0.3 5.6e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAY01469.1 - 4.5e-05 23.5 0.1 0.0001 22.4 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EAY01469.1 - 7.9e-05 22.4 0.4 0.0021 17.7 0.4 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EAY01469.1 - 0.00045 20.4 0.0 0.0026 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 EAY01469.1 - 0.00079 19.6 0.5 0.37 10.9 0.2 2.4 2 0 0 2 2 2 2 Adenylate kinase AAA_7 PF12775.7 EAY01469.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 EAY01469.1 - 0.0022 18.4 0.3 0.053 14.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAY01469.1 - 0.0089 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 EAY01469.1 - 0.011 15.6 1.7 0.54 10.1 0.4 2.8 1 1 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 EAY01469.1 - 0.036 14.5 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EAY01469.1 - 0.037 14.5 0.5 0.076 13.5 0.5 1.9 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 EAY01469.1 - 0.045 13.6 0.7 0.11 12.4 0.1 2.0 2 1 0 2 2 2 0 NTPase AAA_14 PF13173.6 EAY01469.1 - 0.065 13.3 0.1 0.3 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAY01469.1 - 0.072 13.5 0.1 0.12 12.8 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAY01469.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TatD_DNase PF01026.21 EAY01470.1 - 6.8e-27 94.5 0.0 8.1e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase ADH_zinc_N PF00107.26 EAY01471.1 - 1.1e-18 67.5 0.4 1.7e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAY01471.1 - 5.6e-13 48.7 0.1 2.1e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAY01471.1 - 5.9e-06 27.4 0.0 1e-05 26.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAY01471.1 - 0.0083 15.6 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EAY01471.1 - 0.17 11.1 1.9 0.29 10.4 1.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2853 PF11015.8 EAY01472.1 - 0.045 14.4 0.0 0.12 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) PI3Ka PF00613.20 EAY01473.1 - 9.6e-43 145.7 1.0 1.6e-42 145.0 1.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EAY01473.1 - 3.9e-40 138.3 0.0 1.2e-38 133.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EAY01473.1 - 4.5e-17 62.3 0.0 1.3e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Repressor_Mnt PF11423.8 EAY01473.1 - 0.089 12.6 0.1 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 Regulatory protein Mnt PI3K_rbd PF00794.18 EAY01473.1 - 0.094 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain MMR_HSR1_Xtn PF16897.5 EAY01473.1 - 0.12 12.4 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MCM_N PF14551.6 EAY01473.1 - 0.14 12.7 0.0 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 MCM N-terminal domain DUF4135 PF13575.6 EAY01473.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) VPS13 PF16908.5 EAY01474.1 - 1.4e-26 93.7 19.4 1.5e-22 80.6 0.7 5.4 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EAY01474.1 - 8e-19 67.9 0.8 8e-19 67.9 0.8 3.9 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EAY01474.1 - 5.7e-07 29.5 9.7 0.0017 18.2 0.6 3.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EAY01474.1 - 0.00022 21.5 0.1 0.00061 20.1 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Ank_4 PF13637.6 EAY01475.1 - 5.7e-21 74.6 2.9 3e-09 37.2 0.2 3.4 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01475.1 - 8.2e-21 74.4 1.4 6e-12 46.0 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01475.1 - 2.5e-19 67.3 5.3 4.4e-06 26.6 0.2 4.1 3 1 1 4 4 4 4 Ankyrin repeat Ank PF00023.30 EAY01475.1 - 1.4e-17 63.3 3.4 2.8e-05 24.3 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAY01475.1 - 9.7e-11 41.7 2.4 1.1e-05 25.5 0.3 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01476.1 - 3e-11 43.2 0.5 2.3e-06 27.8 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EAY01476.1 - 5.6e-09 36.5 0.7 9e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01476.1 - 1.3e-08 35.3 0.1 1.9e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01476.1 - 8.8e-07 28.8 0.0 0.00059 20.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY01476.1 - 0.00096 19.4 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Elongin_A PF06881.11 EAY01477.1 - 8.2 7.0 11.2 12 6.5 1.6 2.3 1 1 2 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRA-PH PF01503.17 EAY01478.1 - 0.45 11.0 3.6 13 6.3 3.3 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4106 PF13388.6 EAY01479.1 - 3.5e-137 458.1 3.5 6.3e-137 457.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAY01479.1 - 0.0059 16.9 0.3 0.4 11.0 0.2 2.5 2 1 0 2 2 2 1 Kidney androgen-regulated WYL_3 PF18488.1 EAY01479.1 - 0.45 10.9 7.9 6.8 7.1 0.6 3.3 3 0 0 3 3 3 0 WYL domain Phage_fiber_2 PF03406.13 EAY01479.1 - 0.61 9.7 4.9 2.6 7.7 2.6 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Il2rg PF15874.5 EAY01479.1 - 1.9 8.8 5.9 6.7 7.0 0.6 3.0 1 1 2 3 3 3 0 Putative Interleukin 2 receptor, gamma chain Bromodomain PF00439.25 EAY01480.1 - 1.9e-20 72.7 0.8 3.4e-20 71.9 0.8 1.4 1 0 0 1 1 1 1 Bromodomain DUF4446 PF14584.6 EAY01481.1 - 0.00045 20.2 5.4 0.33 10.9 1.9 3.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4446) DUF3377 PF11857.8 EAY01481.1 - 0.021 14.8 4.0 0.17 11.8 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Oxidored_q5_N PF01059.17 EAY01481.1 - 0.088 12.9 0.1 0.088 12.9 0.1 6.7 5 2 0 6 6 6 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus UvrD-helicase PF00580.21 EAY01482.1 - 7.6e-55 186.6 9.8 3.8e-30 105.5 3.4 4.1 2 2 1 3 3 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EAY01482.1 - 7.4e-34 117.2 0.0 2.6e-33 115.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 EAY01482.1 - 5.7e-33 114.7 13.2 7.5e-25 88.0 0.0 3.4 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EAY01482.1 - 2.8e-13 50.2 0.2 9.3e-05 22.3 0.0 3.6 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EAY01482.1 - 1e-11 44.5 0.0 2.3e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EAY01482.1 - 3.3e-10 40.0 0.0 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EAY01482.1 - 0.00085 19.2 0.1 0.00085 19.2 0.1 3.7 3 2 0 3 3 3 1 AAA domain ResIII PF04851.15 EAY01482.1 - 0.0013 18.8 3.0 0.0046 17.0 0.1 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAY01482.1 - 0.0021 18.3 5.8 0.14 12.5 1.3 3.3 3 1 0 3 3 2 1 AAA domain PhoH PF02562.16 EAY01482.1 - 0.0054 16.2 0.3 1.4 8.3 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein SRP_TPR_like PF17004.5 EAY01482.1 - 0.0084 16.1 0.4 0.025 14.6 0.4 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat Flg_hook PF02120.16 EAY01482.1 - 0.071 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK LRR_5 PF13306.6 EAY01483.1 - 4.6e-105 346.7 57.3 7.5e-24 84.1 1.3 7.2 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01483.1 - 1.6e-31 107.9 1.6 0.00058 19.6 0.0 10.1 10 2 2 12 12 12 8 Leucine rich repeat LRR_4 PF12799.7 EAY01483.1 - 0.015 15.7 15.9 2.7 8.5 0.0 8.9 6 4 6 12 12 12 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EAY01483.1 - 0.96 9.7 18.1 1.7 8.9 0.0 6.4 8 0 0 8 8 8 0 FNIP Repeat EF-hand_6 PF13405.6 EAY01484.1 - 9.5e-17 59.4 5.9 0.14 12.2 0.0 7.9 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 EAY01484.1 - 3.8e-07 30.4 24.0 0.03 14.8 0.2 7.0 6 2 2 8 8 8 5 EF-hand domain pair EF-hand_11 PF08976.11 EAY01484.1 - 4.3e-06 27.5 15.3 0.025 15.4 0.2 5.8 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 EAY01484.1 - 6.7e-06 25.3 7.2 2.6 7.8 0.0 7.0 7 0 0 7 7 7 3 EF hand DUF2666 PF10869.8 EAY01484.1 - 5.9e-05 23.3 0.1 27 5.0 0.0 5.8 7 0 0 7 7 7 1 Protein of unknown function (DUF2666) RST PF12174.8 EAY01484.1 - 0.0015 18.4 4.4 0.9 9.5 0.0 4.5 5 0 0 5 5 5 1 RCD1-SRO-TAF4 (RST) plant domain DNA_pol_B_2 PF03175.13 EAY01487.1 - 3.9e-30 105.1 14.0 2e-29 102.8 14.0 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAY01487.1 - 0.16 12.0 0.2 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor DUF3839 PF12943.7 EAY01488.1 - 4.3e-154 511.0 13.5 5.5e-154 510.6 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF1689 PF07954.11 EAY01488.1 - 0.018 15.4 0.8 0.6 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DUF2408 PF10303.9 EAY01488.1 - 4.7 7.8 6.4 1.8 9.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DDE_1 PF03184.19 EAY01489.1 - 1.2e-12 47.9 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Spo0A_C PF08769.11 EAY01489.1 - 0.16 12.0 0.2 0.4 10.8 0.2 1.7 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal MULE PF10551.9 EAY01490.1 - 7.3e-11 42.3 1.9 2.7e-10 40.5 1.2 2.2 2 0 0 2 2 2 1 MULE transposase domain CIDR1_gamma PF18562.1 EAY01490.1 - 0.002 18.2 1.1 0.0083 16.2 1.1 2.1 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma Transposase_mut PF00872.18 EAY01490.1 - 0.0064 15.4 0.2 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Transposase, Mutator family WRKY PF03106.15 EAY01490.1 - 0.081 13.2 2.4 0.098 12.9 0.2 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain Pkinase PF00069.25 EAY01491.1 - 2.3e-70 237.0 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01491.1 - 1.5e-39 135.8 0.0 2.1e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EAY01491.1 - 2.4e-19 69.3 0.5 2.3e-13 50.1 0.1 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EAY01491.1 - 2.2e-11 43.6 0.0 8.1e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 EAY01491.1 - 0.0011 18.7 0.3 0.27 10.8 0.0 2.9 2 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAY01491.1 - 0.0013 17.6 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAY01491.1 - 0.0042 17.0 0.0 0.14 12.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family E2F_TDP PF02319.20 EAY01492.1 - 2.5e-10 40.3 0.1 7e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DUF1298 PF06974.13 EAY01492.1 - 0.0016 18.4 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Ank_4 PF13637.6 EAY01493.1 - 1e-12 48.3 0.3 5.1e-10 39.7 0.0 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01493.1 - 1.2e-10 41.8 2.4 4e-05 24.1 0.1 3.3 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01493.1 - 7e-09 35.2 2.9 0.044 14.3 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAY01493.1 - 0.00024 21.3 0.0 0.0042 17.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MIF4G PF02854.19 EAY01493.1 - 0.019 14.6 0.5 0.019 14.6 0.5 2.0 2 0 0 2 2 2 0 MIF4G domain DUF3447 PF11929.8 EAY01493.1 - 0.038 14.0 1.8 0.064 13.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Ank PF00023.30 EAY01493.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Porin_4 PF13609.6 EAY01494.1 - 6.5e-12 45.8 5.1 3.3e-07 30.4 3.7 3.3 1 1 0 1 1 1 1 Gram-negative porin Bac_rhamnosid_C PF17390.2 EAY01494.1 - 0.00095 18.9 0.0 47 3.9 0.0 5.1 1 1 4 5 5 5 2 Bacterial alpha-L-rhamnosidase C-terminal domain DUF563 PF04577.14 EAY01495.1 - 1.4e-36 126.6 0.6 2e-36 126.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Hamartin PF04388.12 EAY01496.1 - 0.67 8.5 56.4 0.85 8.2 56.4 1.3 1 0 0 1 1 1 0 Hamartin protein GRIP PF01465.20 EAY01497.1 - 7.7e-06 25.7 0.0 2.8e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 EAY01497.1 - 0.00019 20.9 148.6 0.00088 18.7 22.7 6.7 1 1 6 7 7 7 2 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 EAY01497.1 - 0.0017 18.4 8.4 0.0017 18.4 8.4 11.2 4 4 4 8 8 8 2 Centrosomin N-terminal motif 1 ATG16 PF08614.11 EAY01497.1 - 0.0088 16.3 22.1 0.0088 16.3 22.1 6.6 1 1 6 7 7 7 3 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EAY01497.1 - 0.011 16.1 13.8 0.011 16.1 13.8 8.6 1 1 4 7 7 7 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 EAY01497.1 - 0.018 15.3 13.2 0.018 15.3 13.2 9.2 1 1 8 9 9 9 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EAY01497.1 - 0.8 9.8 140.9 0.27 11.3 18.4 8.1 1 1 6 7 7 7 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EAY01497.1 - 0.83 9.2 126.9 0.06 12.9 50.6 4.8 1 1 3 4 4 4 0 Intermediate filament protein Vps53_N PF04100.12 EAY01498.1 - 7.6e-62 209.5 11.3 7.6e-62 209.5 11.3 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 EAY01498.1 - 2.4e-06 27.1 8.7 2.4e-06 27.1 8.7 2.2 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF4363 PF14276.6 EAY01498.1 - 9.3e-06 25.7 1.0 9.3e-06 25.7 1.0 4.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4363) TACC_C PF05010.14 EAY01498.1 - 0.0011 18.8 3.4 0.0011 18.8 3.4 2.4 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 EAY01498.1 - 0.003 16.5 5.4 0.003 16.5 5.4 2.1 2 1 0 2 2 2 1 Spc7 kinetochore protein DUF3450 PF11932.8 EAY01498.1 - 0.068 12.5 3.5 0.18 11.1 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COG5 PF10392.9 EAY01498.1 - 0.55 10.4 10.7 0.1 12.8 4.5 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 COG2 PF06148.11 EAY01498.1 - 1.2 9.3 4.8 0.67 10.0 1.7 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CRR7 PF12095.8 EAY01498.1 - 4.1 7.9 5.7 5.2 7.6 0.1 3.6 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF2884 PF11101.8 EAY01498.1 - 6 6.3 11.3 0.41 10.1 1.8 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2884) Ank_2 PF12796.7 EAY01499.1 - 1.3e-86 285.2 0.9 7.6e-19 68.1 0.1 4.9 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01499.1 - 1.9e-35 120.8 0.0 3.7e-10 40.1 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01499.1 - 4.5e-35 118.6 0.0 2.9e-05 24.3 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 EAY01499.1 - 1.6e-34 117.5 0.1 7.1e-07 29.4 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01499.1 - 3e-32 107.0 0.0 0.00096 19.4 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Syntaxin_2 PF14523.6 EAY01499.1 - 0.046 14.1 5.1 0.041 14.3 2.3 2.1 1 1 1 2 2 2 0 Syntaxin-like protein TRAF_BIRC3_bd PF16673.5 EAY01499.1 - 1.4 8.7 3.5 0.94 9.3 0.3 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Ank_2 PF12796.7 EAY01500.1 - 1.3e-24 86.5 0.1 7.8e-18 64.9 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01500.1 - 1.2e-18 67.0 0.1 1e-05 25.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01500.1 - 7.2e-18 64.2 0.0 0.00031 21.0 0.0 5.0 5 0 0 5 5 4 3 Ankyrin repeat Ank_3 PF13606.6 EAY01500.1 - 7.3e-17 59.7 0.1 0.0054 17.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAY01500.1 - 4.4e-16 59.0 0.0 1.8e-05 25.2 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) LMBR1 PF04791.16 EAY01500.1 - 0.042 12.8 1.7 0.054 12.4 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 EAY01500.1 - 0.074 13.5 7.6 0.18 12.3 7.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF3450 PF11932.8 EAY01500.1 - 0.092 12.0 4.6 0.14 11.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Bap31_Bap29_C PF18035.1 EAY01500.1 - 0.13 12.3 11.2 0.067 13.2 7.5 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain BUD22 PF09073.10 EAY01500.1 - 0.19 11.0 3.6 0.29 10.4 3.6 1.2 1 0 0 1 1 1 0 BUD22 Takusan PF04822.13 EAY01500.1 - 0.41 10.5 7.7 0.17 11.8 4.4 2.0 1 1 1 2 2 2 0 Takusan WD40_alt PF14077.6 EAY01500.1 - 0.85 9.5 4.3 0.21 11.5 0.6 1.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif APG6_N PF17675.1 EAY01500.1 - 1.5 9.3 9.7 3.3 8.3 9.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 EAY01500.1 - 3.9 8.2 7.4 4.1 8.1 3.5 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Ribonuc_2-5A PF06479.12 EAY01501.1 - 0.029 14.5 0.7 0.029 14.5 0.7 3.7 2 1 1 3 3 3 0 Ribonuclease 2-5A PHA_synth_III_E PF09712.10 EAY01501.1 - 0.04 13.0 0.1 0.04 13.0 0.1 2.9 3 0 0 3 3 3 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Vps51 PF08700.11 EAY01501.1 - 0.049 13.7 0.3 0.049 13.7 0.3 8.9 7 5 3 10 10 10 0 Vps51/Vps67 Pro_sub2 PF18513.1 EAY01501.1 - 0.098 12.8 0.0 0.098 12.8 0.0 5.1 5 0 0 5 5 5 0 Prodomain subtilisin 2 DUF563 PF04577.14 EAY01502.1 - 2.4e-36 125.8 0.5 3.6e-36 125.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) NADHdeh_related PF10125.9 EAY01502.1 - 0.095 12.1 0.4 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein Thioredoxin_14 PF18402.1 EAY01503.1 - 3.1e-29 102.7 6.2 6.3e-28 98.4 0.6 3.4 2 1 0 3 3 3 2 Thioredoxin-like domain Glyco_transf_24 PF18404.1 EAY01503.1 - 1.6e-17 63.8 0.0 3.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_13 PF18401.1 EAY01503.1 - 7.1e-11 42.2 0.7 2.1e-10 40.7 0.3 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EAY01503.1 - 0.094 12.6 0.4 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like domain zf-C3HC4_3 PF13920.6 EAY01505.1 - 2.5e-09 36.9 24.8 2.5e-09 36.9 24.8 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Beta_helix PF13229.6 EAY01505.1 - 1.1e-05 25.4 28.4 4.3e-05 23.4 10.3 3.1 1 1 1 3 3 3 3 Right handed beta helix region PIF6 PF05341.11 EAY01505.1 - 0.05 13.7 0.2 0.32 11.1 0.1 2.2 1 1 1 2 2 2 0 Per os infectivity factor 6 Prok-RING_4 PF14447.6 EAY01505.1 - 4.9 7.1 42.8 0.95 9.4 24.3 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 MIG-14_Wnt-bd PF06664.12 EAY01506.1 - 1.4e-08 34.4 40.9 2.6e-08 33.4 40.9 1.5 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Ribosomal_S14 PF00253.21 EAY01507.1 - 1.9e-14 53.2 5.2 2.1e-14 53.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS91 PF14319.6 EAY01507.1 - 0.034 14.2 1.0 0.037 14.1 1.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_2 PF13696.6 EAY01507.1 - 2.2 8.2 7.5 8.4 6.3 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle SWIRM PF04433.17 EAY01508.1 - 0.017 15.4 3.0 0.48 10.8 3.0 2.5 1 1 0 1 1 1 0 SWIRM domain DUF4476 PF14771.6 EAY01508.1 - 0.049 13.9 0.4 0.074 13.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Ank_4 PF13637.6 EAY01509.1 - 1.2e-16 60.8 0.3 8.1e-09 35.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01509.1 - 1.3e-16 60.5 0.1 7.9e-11 42.0 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01509.1 - 4.5e-13 49.0 1.6 3.4e-09 36.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAY01509.1 - 1.5e-10 41.5 0.2 2.6e-10 40.8 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01509.1 - 5.8e-10 38.5 0.7 1.1e-06 28.5 0.0 2.8 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 EAY01509.1 - 1.2e-05 25.2 1.1 1.2e-05 25.2 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) PH_8 PF15409.6 EAY01509.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_6 PF13516.6 EAY01510.1 - 1 9.6 8.3 13 6.1 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Pkinase PF00069.25 EAY01511.1 - 6.9e-60 202.6 0.0 8.3e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01511.1 - 7.3e-29 100.8 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAY01511.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAY01511.1 - 0.00024 20.5 0.0 0.0012 18.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EAY01511.1 - 0.0017 18.0 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAY01511.1 - 0.024 14.2 0.0 0.068 12.8 0.0 1.6 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EAY01511.1 - 0.092 11.5 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase HSP70 PF00012.20 EAY01512.1 - 1.9e-92 310.4 7.6 1.9e-92 310.4 7.6 3.7 3 1 0 3 3 3 1 Hsp70 protein Ribosomal_L1 PF00687.21 EAY01513.1 - 1.1e-33 116.7 4.4 1.3e-33 116.4 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Sec10 PF07393.11 EAY01513.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 E1_DerP2_DerF2 PF02221.15 EAY01515.1 - 1.3e-07 32.1 0.0 1.6e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 ML domain Thioredoxin PF00085.20 EAY01516.1 - 1.2e-12 47.7 1.4 2.4e-07 30.7 0.5 2.4 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 EAY01516.1 - 2.5e-07 30.6 0.8 0.00063 19.6 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29 PF07749.12 EAY01516.1 - 0.0003 21.6 0.3 0.00099 20.0 0.3 2.0 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ALIX_LYPXL_bnd PF13949.6 EAY01516.1 - 0.017 14.4 0.4 0.029 13.7 0.4 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Redoxin PF08534.10 EAY01516.1 - 0.025 14.3 0.1 0.33 10.7 0.1 2.3 2 0 0 2 2 2 0 Redoxin OST3_OST6 PF04756.13 EAY01516.1 - 0.051 12.9 1.2 0.087 12.2 0.7 1.6 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAY01516.1 - 0.06 13.8 0.4 4.8 7.7 0.9 3.1 2 2 0 2 2 2 0 Thioredoxin-like domain DUF3447 PF11929.8 EAY01517.1 - 9.4e-29 99.2 3.1 9.4e-29 99.2 3.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3452 PF11934.8 EAY01517.1 - 0.075 12.6 0.4 0.16 11.6 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Ank PF00023.30 EAY01518.1 - 6.6e-18 64.3 4.8 4.1e-05 23.8 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAY01518.1 - 1.4e-17 62.0 4.2 7.4e-05 22.9 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EAY01518.1 - 3.1e-17 62.9 7.0 1.2e-10 41.9 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01518.1 - 1.1e-15 57.5 12.7 9.5e-08 32.2 0.3 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01518.1 - 5.7e-14 52.3 2.1 4.3e-10 39.9 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3895 PF13034.6 EAY01518.1 - 0.029 14.4 0.3 4.1 7.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3895) GPS2_interact PF15784.5 EAY01519.1 - 0.094 13.2 1.4 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01519.1 - 0.15 11.0 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAY01520.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01520.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAS_N PF17828.1 EAY01521.1 - 0.012 15.7 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAY01522.1 - 0.017 15.5 0.5 0.02 15.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAY01523.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAY01523.1 - 0.074 13.0 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PapD_N PF00345.20 EAY01525.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2939 PF11159.8 EAY01526.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY01526.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAY01527.1 - 0.0093 16.0 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta DUF4140 PF13600.6 EAY01527.1 - 0.046 14.2 0.6 0.067 13.6 0.6 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Trypan_PARP PF05887.11 EAY01529.1 - 0.069 13.1 13.0 0.072 13.1 13.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01529.1 - 2.7 8.4 6.6 3 8.3 6.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY01530.1 - 0.072 13.5 1.0 0.095 13.1 1.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF3447 PF11929.8 EAY01531.1 - 1.9e-35 120.6 3.3 1.9e-35 120.6 3.3 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01531.1 - 0.0037 17.8 0.1 0.3 11.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01532.1 - 2.5e-49 165.0 9.7 7.8e-12 45.5 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01532.1 - 3.7e-47 158.8 29.8 3.8e-14 53.0 2.5 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01532.1 - 3.3e-35 119.0 4.4 3.6e-07 30.4 0.1 5.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAY01532.1 - 1.8e-31 104.6 4.6 5.1e-06 26.4 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAY01532.1 - 2.8e-25 88.1 7.7 4e-10 39.7 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PhetRS_B1 PF18262.1 EAY01532.1 - 0.0092 16.2 4.1 1.9 8.8 0.2 3.2 1 1 1 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain PH_8 PF15409.6 EAY01532.1 - 0.011 16.0 0.2 5.1 7.5 0.0 3.2 1 1 2 3 3 3 0 Pleckstrin homology domain Clathrin_bdg PF15045.6 EAY01532.1 - 0.016 15.2 0.1 0.25 11.4 0.0 2.3 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Aldolase PF01081.19 EAY01532.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.7 1 1 0 1 1 1 0 KDPG and KHG aldolase BRCT_2 PF16589.5 EAY01532.1 - 0.25 11.8 2.4 9.7 6.7 0.1 3.0 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Prominin PF05478.11 EAY01533.1 - 0.79 7.6 8.7 1.1 7.1 8.7 1.1 1 0 0 1 1 1 0 Prominin Orf78 PF06024.12 EAY01536.1 - 0.024 14.9 0.7 0.068 13.5 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DUF4307 PF14155.6 EAY01536.1 - 0.16 11.8 0.0 0.57 10.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Serinc PF03348.15 EAY01536.1 - 0.38 9.6 4.7 2.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Serine incorporator (Serinc) Ank PF00023.30 EAY01537.1 - 2.6e-47 157.3 13.3 2e-08 34.3 0.2 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 EAY01537.1 - 7.1e-47 157.2 8.8 2.8e-09 37.3 0.0 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01537.1 - 1.8e-46 155.6 15.6 8.8e-11 41.8 0.1 5.5 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01537.1 - 3e-45 152.7 14.7 1.7e-17 63.8 0.7 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01537.1 - 3e-33 110.1 13.3 1.2e-05 25.2 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ribosomal_S6 PF01250.17 EAY01537.1 - 0.074 13.3 0.3 7.6 6.9 0.1 3.0 2 2 0 3 3 3 0 Ribosomal protein S6 ArlS_N PF18719.1 EAY01537.1 - 0.092 13.0 1.1 0.53 10.5 0.2 2.6 2 1 2 4 4 4 0 ArlS sensor domain tRNA-synt_1 PF00133.22 EAY01538.1 - 4.5e-27 94.6 0.0 2.8e-14 52.3 0.1 2.1 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAY01538.1 - 8.9e-11 41.2 0.0 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAY01539.1 - 3.3e-08 33.6 0.3 5.6e-08 32.9 0.2 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA Ank_2 PF12796.7 EAY01540.1 - 1.9e-90 297.6 48.4 3.3e-19 69.2 5.3 8.7 3 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01540.1 - 3.1e-86 282.7 31.3 2.1e-13 50.5 0.0 14.2 5 3 10 15 15 15 12 Ankyrin repeats (many copies) Ank PF00023.30 EAY01540.1 - 7.4e-82 266.5 39.2 1.3e-07 31.7 0.0 16.3 17 0 0 17 17 17 13 Ankyrin repeat Ank_3 PF13606.6 EAY01540.1 - 7.4e-68 216.4 46.0 1e-05 25.5 0.1 17.6 18 1 1 19 19 19 13 Ankyrin repeat Ank_5 PF13857.6 EAY01540.1 - 1.7e-60 200.2 31.3 1.1e-10 41.5 0.2 10.8 7 3 6 13 13 13 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01540.1 - 4.3e-38 129.1 5.7 4.3e-38 129.1 5.7 7.4 7 2 3 10 10 10 2 Domain of unknown function (DUF3447) CEP44 PF15007.6 EAY01540.1 - 0.0013 18.9 3.6 18 5.5 0.1 6.4 3 2 4 7 7 7 1 Centrosomal spindle body, CEP44 PP2C PF00481.21 EAY01541.1 - 3.3e-44 151.5 0.0 4.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAY01541.1 - 2.3e-35 120.2 52.9 2.6e-08 33.5 2.8 11.3 6 3 4 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EAY01541.1 - 8.7e-24 83.2 65.1 0.0012 19.2 0.1 12.3 7 2 8 15 15 15 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY01541.1 - 2.7e-07 30.3 10.7 5.7e-05 22.7 0.7 4.5 3 2 1 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 EAY01541.1 - 0.00015 21.6 38.9 1.2 9.4 0.0 11.8 15 0 0 15 15 15 5 Leucine Rich repeat PP2C_2 PF13672.6 EAY01541.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C LRR_5 PF13306.6 EAY01541.1 - 7.7 6.5 25.7 1 9.3 3.2 4.6 3 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Gly-zipper_Omp PF13488.6 EAY01542.1 - 0.006 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 EAY01542.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY01542.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAY01544.1 - 3.5e-06 26.7 0.5 4.1e-06 26.4 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein DUF1722 PF08349.11 EAY01544.1 - 0.13 12.6 1.5 0.12 12.6 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) T5orf172 PF10544.9 EAY01545.1 - 3.2e-05 24.4 0.1 6.7e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 T5orf172 domain TPR_MLP1_2 PF07926.12 EAY01546.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY01546.1 - 0.043 13.6 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY01546.1 - 0.36 10.8 7.7 0.16 11.9 2.9 2.3 3 0 0 3 3 3 0 Spo12 family Ank_2 PF12796.7 EAY01547.1 - 2.9e-49 165.6 14.0 1.8e-16 60.5 0.6 6.2 2 2 5 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01547.1 - 3e-42 141.2 4.3 3e-07 30.6 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAY01547.1 - 1.5e-40 137.1 13.0 1.7e-13 50.8 0.2 8.7 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01547.1 - 3.3e-37 122.3 10.1 3.7e-05 23.8 0.0 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EAY01547.1 - 2.2e-29 101.1 1.6 4.5e-09 36.4 0.0 7.9 4 2 4 8 8 8 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01547.1 - 1.7e-18 66.4 5.0 1.7e-18 66.4 5.0 5.4 4 1 3 7 7 7 2 Domain of unknown function (DUF3447) DUF655 PF04919.12 EAY01547.1 - 0.055 13.4 0.0 0.58 10.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF655) Ank PF00023.30 EAY01548.1 - 4.3e-43 143.9 13.6 3.3e-08 33.6 0.1 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAY01548.1 - 3.1e-42 142.1 2.2 4.2e-11 42.9 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01548.1 - 5.1e-41 139.1 2.8 1.3e-16 60.9 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01548.1 - 1.5e-39 133.9 4.9 3.6e-07 30.6 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01548.1 - 3.8e-34 112.9 7.5 3.1e-06 27.1 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat GATase_7 PF13537.6 EAY01548.1 - 0.00013 21.8 0.1 10 6.0 0.0 4.9 5 1 1 6 6 6 1 Glutamine amidotransferase domain MetallophosN PF16371.5 EAY01548.1 - 0.018 15.3 0.0 14 6.0 0.0 3.3 1 1 2 3 3 3 0 N terminal of Calcineurin-like phosphoesterase PEGA PF08308.11 EAY01548.1 - 0.019 14.8 0.0 20 5.2 0.0 4.0 5 0 0 5 5 5 0 PEGA domain ParA PF10609.9 EAY01549.1 - 3.3e-54 183.9 0.2 5.4e-54 183.3 0.2 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAY01549.1 - 1.4e-07 31.6 0.2 8e-07 29.2 0.2 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EAY01549.1 - 1.7e-06 27.7 0.2 0.019 14.5 0.0 2.7 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EAY01549.1 - 1.7e-06 27.5 0.0 3.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EAY01549.1 - 1.3e-05 24.5 5.2 0.00047 19.4 0.1 3.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 EAY01549.1 - 9.1e-05 22.4 7.4 0.00024 21.1 3.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAY01549.1 - 0.0056 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NAD_binding_10 PF13460.6 EAY01549.1 - 0.063 13.2 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Tex_YqgF PF16921.5 EAY01549.1 - 0.075 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain CBP_BcsQ PF06564.12 EAY01549.1 - 0.14 11.6 0.7 6.2 6.2 0.3 2.6 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ YebO PF13974.6 EAY01549.1 - 0.3 11.2 10.3 0.7 10.0 10.3 1.6 1 0 0 1 1 1 0 YebO-like protein RRF PF01765.19 EAY01549.1 - 0.31 11.0 12.4 0.53 10.2 12.4 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Chlam_PMP PF02415.17 EAY01550.1 - 5.2 7.8 10.8 12 6.6 0.0 4.4 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PSP PF04046.16 EAY01551.1 - 0.068 13.1 0.8 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY01552.1 - 0.1 13.2 4.6 13 7.0 0.1 3.4 3 1 0 3 3 3 0 TMP repeat P22_AR_C PF10548.9 EAY01553.1 - 0.11 12.7 0.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain PRA-PH PF01503.17 EAY01556.1 - 0.52 10.8 3.1 10 6.6 3.5 2.5 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase ACP_PD PF04336.12 EAY01558.1 - 0.047 14.1 0.1 1.4 9.4 0.0 3.2 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase Meiosis_expr PF15163.6 EAY01559.1 - 0.022 15.4 0.8 0.035 14.8 0.3 1.6 2 0 0 2 2 2 0 Meiosis-expressed PHP_C PF13263.6 EAY01559.1 - 0.17 11.6 0.1 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 PHP-associated Spo12 PF05032.12 EAY01559.1 - 1.5 8.8 11.1 0.14 12.0 2.8 3.1 4 1 0 4 4 4 0 Spo12 family Pox_A32 PF04665.12 EAY01562.1 - 8.6e-05 22.1 4.0 0.00016 21.2 4.0 1.6 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY01562.1 - 0.0058 16.6 0.9 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAY01562.1 - 0.0096 15.5 0.2 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAY01562.1 - 0.053 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 UCH PF00443.29 EAY01563.1 - 2.3e-68 230.5 0.8 2.8e-68 230.2 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAY01563.1 - 1.3e-14 54.5 0.2 4.4e-14 52.9 0.2 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EAY01563.1 - 3.3e-11 43.3 0.5 3.3e-07 30.2 0.2 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAY01563.1 - 0.06 12.7 0.7 0.11 11.8 0.3 1.6 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-ISL3 PF14690.6 EAY01563.1 - 0.21 12.3 3.3 12 6.7 1.9 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 EAY01563.1 - 0.87 9.1 4.1 6.5 6.3 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 EAY01563.1 - 4.2 7.2 5.8 1.1 9.0 0.2 2.5 3 0 0 3 3 3 0 Ribosomal protein S27 zf-MIZ PF02891.20 EAY01563.1 - 8.6 6.2 12.4 0.086 12.6 1.2 3.0 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger YL1 PF05764.13 EAY01564.1 - 0.022 14.9 13.4 0.026 14.7 13.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Ntox23 PF15528.6 EAY01564.1 - 0.03 14.5 2.3 0.04 14.1 2.3 1.2 1 0 0 1 1 1 0 Bacterial toxin 23 Mif2_N PF15624.6 EAY01564.1 - 0.083 13.6 3.1 0.094 13.4 3.1 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Osteopontin PF00865.18 EAY01564.1 - 0.43 10.0 17.6 0.51 9.8 17.6 1.2 1 0 0 1 1 1 0 Osteopontin TMEM43 PF07787.12 EAY01564.1 - 0.95 8.8 2.9 1.1 8.6 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 CDC45 PF02724.14 EAY01564.1 - 1.6 6.9 12.4 1.8 6.7 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EAY01564.1 - 2.3 6.2 15.4 2.3 6.2 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EAY01564.1 - 2.6 6.1 15.5 2.8 6.0 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EAY01564.1 - 2.8 6.4 12.1 2.9 6.3 12.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Gly_rich PF12810.7 EAY01565.1 - 3.9e-36 125.2 35.5 5.1e-36 124.8 35.5 1.1 1 0 0 1 1 1 1 Glycine rich protein YL1 PF05764.13 EAY01566.1 - 0.014 15.5 10.4 0.016 15.4 10.4 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Rsc14 PF08586.10 EAY01566.1 - 0.61 10.9 4.3 0.34 11.7 1.5 1.8 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit CDC45 PF02724.14 EAY01566.1 - 2.2 6.4 9.5 2.6 6.2 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EAY01566.1 - 3.8 5.9 10.1 4 5.9 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EAY01566.1 - 4.6 5.2 12.3 4.8 5.2 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EAY01567.1 - 2.1 6.6 11.4 2.4 6.4 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EAY01567.1 - 4.6 5.7 10.2 4.9 5.6 10.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOP19 PF10863.8 EAY01567.1 - 7.1 6.5 16.8 92 2.8 16.8 2.1 1 1 0 1 1 1 0 Nucleolar protein 19 Ank_5 PF13857.6 EAY01568.1 - 6.8e-13 48.6 0.0 1e-07 32.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01568.1 - 7.8e-11 42.4 0.0 9.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01568.1 - 1.4e-08 35.1 0.0 2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01568.1 - 2.2e-07 30.6 0.0 0.006 17.0 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAY01568.1 - 2.7e-06 27.5 0.0 0.00014 22.1 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.25 EAY01569.1 - 6.5e-72 242.1 0.3 8.9e-72 241.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01569.1 - 5.3e-40 137.3 0.0 7.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAY01569.1 - 7.2e-05 23.4 0.1 0.00015 22.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EAY01569.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAY01569.1 - 0.0023 16.9 0.4 0.0034 16.4 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY01569.1 - 0.032 13.6 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 EAY01569.1 - 0.064 13.8 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 PH domain Pkinase_fungal PF17667.1 EAY01569.1 - 0.094 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PH_2 PF08458.10 EAY01569.1 - 0.17 12.3 2.8 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Ten1_2 PF15490.6 EAY01570.1 - 4e-08 33.0 0.0 5.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 EAY01570.1 - 0.00038 20.8 0.0 0.0005 20.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 RMI2 PF16100.5 EAY01570.1 - 0.18 11.6 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 PAS_9 PF13426.7 EAY01571.1 - 1.2e-10 41.6 0.6 3e-10 40.3 0.6 1.8 1 0 0 1 1 1 1 PAS domain Guanylate_cyc PF00211.20 EAY01571.1 - 5e-07 29.5 0.0 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 EAY01571.1 - 0.013 15.5 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 0 PAS domain HNOBA PF07701.14 EAY01571.1 - 0.026 13.9 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Heme NO binding associated P53_C PF11619.8 EAY01571.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DHR-2 PF06920.13 EAY01572.1 - 2.5e-12 46.3 11.4 2.5e-12 46.3 11.4 2.0 2 1 0 2 2 2 1 Dock homology region 2 mCpol PF18182.1 EAY01572.1 - 1 9.7 3.0 0.95 9.8 0.3 2.3 2 0 0 2 2 2 0 minimal CRISPR polymerase domain SlyX PF04102.12 EAY01574.1 - 0.025 15.2 0.8 0.025 15.2 0.8 3.2 2 1 1 3 3 3 0 SlyX Scm3 PF10384.9 EAY01574.1 - 0.29 10.9 6.4 0.55 10.0 0.2 3.5 3 1 1 4 4 4 0 Centromere protein Scm3 FAM184 PF15665.5 EAY01574.1 - 1.5 8.6 28.4 9 6.0 16.8 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B SLATT_1 PF18181.1 EAY01574.1 - 5.5 6.9 7.3 0.37 10.7 0.5 2.2 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 RhoGEF PF00621.20 EAY01575.1 - 3.1e-35 122.1 4.8 6.1e-35 121.1 4.8 1.5 1 0 0 1 1 1 1 RhoGEF domain Kelch_4 PF13418.6 EAY01575.1 - 1e-25 89.4 4.5 2.3e-06 27.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EAY01575.1 - 3.6e-23 81.1 1.3 1.1e-06 28.5 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EAY01575.1 - 2.9e-21 74.8 0.0 1e-06 28.2 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EAY01575.1 - 3.2e-20 71.9 0.0 0.00082 19.6 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAY01575.1 - 9.5e-19 67.0 2.0 8.6e-06 25.9 0.0 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAY01575.1 - 2.5e-18 65.2 0.2 6.2e-06 26.0 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Pkinase PF00069.25 EAY01576.1 - 6.9e-68 228.9 0.0 9.5e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01576.1 - 2.8e-44 151.4 0.0 3.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01576.1 - 4.6e-06 26.2 0.0 1.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAY01576.1 - 0.00016 21.7 0.0 0.008 16.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAY01576.1 - 0.00062 18.8 0.2 0.0018 17.3 0.0 1.8 1 1 1 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAY01576.1 - 0.00096 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAY01576.1 - 0.0018 17.4 0.2 0.0058 15.7 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 APG6_N PF17675.1 EAY01576.1 - 0.0038 17.8 2.9 0.012 16.2 1.9 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region FliG_C PF01706.16 EAY01576.1 - 0.063 13.5 0.8 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 FliG C-terminal domain ZapB PF06005.12 EAY01576.1 - 0.097 13.1 7.9 0.19 12.2 7.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 EAY01576.1 - 1.6 9.0 11.8 0.81 10.0 7.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Y_Y_Y PF07495.13 EAY01577.1 - 9.3e-06 25.5 2.5 0.23 11.4 0.0 5.3 3 0 0 3 3 3 2 Y_Y_Y domain DUF4625 PF15418.6 EAY01577.1 - 0.00015 22.0 13.2 0.2 11.9 0.2 6.0 4 3 0 4 4 4 3 Domain of unknown function (DUF4625) Sod_Cu PF00080.20 EAY01577.1 - 0.019 15.1 0.3 55 3.9 0.0 3.9 4 0 0 4 4 4 0 Copper/zinc superoxide dismutase (SODC) DUF4399 PF14347.6 EAY01577.1 - 0.074 13.4 0.1 21 5.5 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) E1_DerP2_DerF2 PF02221.15 EAY01577.1 - 0.16 12.4 6.7 40 4.7 0.1 5.4 5 1 0 5 5 5 0 ML domain CHB_HEX_C_1 PF13290.6 EAY01577.1 - 4.6 7.3 20.6 29 4.8 0.0 6.3 6 1 0 6 6 6 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF4625 PF15418.6 EAY01578.1 - 6e-06 26.5 12.0 0.37 11.0 0.0 6.6 4 2 1 5 5 5 4 Domain of unknown function (DUF4625) Y_Y_Y PF07495.13 EAY01578.1 - 0.3 11.1 10.9 0.36 10.8 0.1 4.7 5 0 0 5 5 5 0 Y_Y_Y domain TMEM154 PF15102.6 EAY01579.1 - 3.5e-06 27.0 0.8 5.9e-06 26.2 0.8 1.4 1 0 0 1 1 1 1 TMEM154 protein family TMEM51 PF15345.6 EAY01579.1 - 0.00078 19.3 0.2 0.0011 18.8 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Glycophorin_A PF01102.18 EAY01579.1 - 0.0016 18.7 0.2 0.0031 17.7 0.2 1.6 1 1 0 1 1 1 1 Glycophorin A EphA2_TM PF14575.6 EAY01579.1 - 0.0022 18.8 0.7 0.0038 18.1 0.1 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 EAY01579.1 - 0.0032 18.0 5.1 0.031 14.9 0.1 2.2 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF2207 PF09972.9 EAY01579.1 - 0.0033 16.3 0.0 0.0055 15.5 0.0 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Shisa PF13908.6 EAY01579.1 - 0.0036 17.6 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Syndecan PF01034.20 EAY01579.1 - 0.0046 16.8 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain ECSCR PF15820.5 EAY01579.1 - 0.0084 15.9 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator RskA PF10099.9 EAY01579.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Orf78 PF06024.12 EAY01579.1 - 0.02 15.2 0.2 0.047 14.0 0.1 1.9 1 1 1 2 2 2 0 Orf78 (ac78) DUF5305 PF17231.2 EAY01579.1 - 0.021 14.2 0.3 0.021 14.2 0.3 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5305) Mid2 PF04478.12 EAY01579.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3169 PF11368.8 EAY01579.1 - 0.03 13.8 0.7 0.071 12.6 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) CbtA PF09490.10 EAY01579.1 - 0.03 14.1 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Amnionless PF14828.6 EAY01579.1 - 0.036 12.9 0.5 0.061 12.1 0.2 1.5 1 1 1 2 2 2 0 Amnionless Protocadherin PF08374.11 EAY01579.1 - 0.063 13.3 2.0 0.066 13.2 1.2 1.4 1 1 0 1 1 1 0 Protocadherin MscL PF01741.18 EAY01579.1 - 0.068 13.5 2.6 0.099 12.9 2.3 1.4 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF4662 PF15578.6 EAY01579.1 - 0.1 12.4 1.1 0.17 11.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF3357 PF11837.8 EAY01579.1 - 0.11 13.0 0.3 0.2 12.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Herpes_gE PF02480.16 EAY01579.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Podoplanin PF05808.11 EAY01579.1 - 0.3 11.2 5.6 0.047 13.8 1.0 1.8 1 1 1 2 2 2 0 Podoplanin TMEM171 PF15471.6 EAY01579.1 - 0.31 10.0 2.1 0.2 10.6 0.5 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 SARAF PF06682.12 EAY01579.1 - 0.33 10.6 1.1 0.56 9.8 0.4 1.6 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4366 PF14283.6 EAY01579.1 - 0.38 10.8 7.4 0.035 14.1 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) LRR19-TM PF15176.6 EAY01579.1 - 0.68 10.0 3.0 0.43 10.6 1.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Chordopox_A13L PF05961.11 EAY01579.1 - 1.1 9.5 4.3 0.63 10.3 0.4 2.3 2 1 1 3 3 3 0 Chordopoxvirus A13L protein DUF3377 PF11857.8 EAY01579.1 - 6.6 6.7 6.9 0.39 10.7 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3377) BRE1 PF08647.11 EAY01580.1 - 0.00013 22.0 17.5 0.00013 22.0 17.5 11.2 5 4 5 11 11 11 1 BRE1 E3 ubiquitin ligase Takusan PF04822.13 EAY01580.1 - 0.019 14.8 1.4 0.019 14.8 1.4 8.8 7 3 3 10 10 10 0 Takusan UCH PF00443.29 EAY01583.1 - 6.5e-35 120.9 4.1 1.2e-34 119.9 0.8 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAY01583.1 - 2.5e-07 30.6 2.1 0.0059 16.2 1.6 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3644 PF12358.8 EAY01584.1 - 6.9 7.2 10.8 0.32 11.5 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) Ank_4 PF13637.6 EAY01586.1 - 4.6e-19 68.5 0.4 3.3e-06 27.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01586.1 - 5.8e-15 55.7 0.4 8.3e-13 48.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01586.1 - 3.8e-13 49.4 0.1 2e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01586.1 - 1.5e-12 47.4 0.0 0.00055 20.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAY01586.1 - 4.9e-08 32.6 0.1 0.029 14.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EAY01587.1 - 7.6e-10 38.6 0.1 7.6e-10 38.6 0.1 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3783 PF12646.7 EAY01587.1 - 0.024 14.6 1.2 0.081 12.9 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3783) VraX PF17412.2 EAY01587.1 - 0.1 12.3 1.3 0.3 10.7 0.1 2.4 2 1 0 2 2 2 0 Family of unknown function Ank_2 PF12796.7 EAY01587.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4576 PF15144.6 EAY01588.1 - 0.088 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Mid2 PF04478.12 EAY01589.1 - 4.7e-05 23.3 2.4 0.0001 22.1 2.4 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 EAY01589.1 - 0.00018 22.3 0.1 0.00039 21.2 0.1 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 EAY01589.1 - 0.0004 20.3 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Protocadherin PF08374.11 EAY01589.1 - 0.00042 20.4 1.0 0.00094 19.2 0.8 1.6 1 1 0 1 1 1 1 Protocadherin FAM176 PF14851.6 EAY01589.1 - 0.00054 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 FAM176 family Herpes_gE PF02480.16 EAY01589.1 - 0.0019 17.1 0.1 0.0041 15.9 0.0 1.5 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 EAY01589.1 - 0.0023 17.9 0.6 0.0023 17.9 0.6 2.8 1 1 2 3 3 3 1 TMEM154 protein family DUF4834 PF16118.5 EAY01589.1 - 0.0024 18.8 0.2 0.0067 17.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4514 PF14986.6 EAY01589.1 - 0.0029 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4514) Shisa PF13908.6 EAY01589.1 - 0.0031 17.8 0.1 0.0066 16.7 0.1 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 EAY01589.1 - 0.0058 15.1 1.9 0.0069 14.9 1.9 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Zip PF02535.22 EAY01589.1 - 0.0081 15.4 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Transglut_N PF00868.20 EAY01589.1 - 0.0098 16.2 0.2 0.027 14.8 0.2 1.8 1 1 0 1 1 1 1 Transglutaminase family PRIMA1 PF16101.5 EAY01589.1 - 0.01 15.8 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Syndecan PF01034.20 EAY01589.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain MLANA PF14991.6 EAY01589.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.7 2 0 0 2 2 1 0 Protein melan-A MAP17 PF15807.5 EAY01589.1 - 0.042 14.1 0.4 0.042 14.1 0.4 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cadherin_C_2 PF16492.5 EAY01589.1 - 0.048 14.4 0.1 0.57 11.0 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4820 PF16091.5 EAY01589.1 - 0.15 11.4 1.0 0.31 10.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CRA PF06589.11 EAY01589.1 - 0.32 11.1 9.7 0.05 13.7 5.3 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) PTR PF12789.7 EAY01590.1 - 7.4e-22 77.2 6.6 7.4e-22 77.2 6.6 4.2 3 1 1 4 4 4 2 Phage tail repeat like DUF1493 PF07377.12 EAY01591.1 - 0.022 15.2 0.4 0.048 14.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4272 PF14094.6 EAY01592.1 - 1.6e-33 115.7 0.8 1.3e-32 112.8 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4272) Pyr_redox_2 PF07992.14 EAY01593.1 - 1.3e-53 182.2 0.4 1.8e-53 181.7 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAY01593.1 - 2.8e-34 117.7 1.8 5.8e-34 116.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAY01593.1 - 6.1e-21 74.8 3.4 3.4e-18 66.0 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAY01593.1 - 2.6e-11 43.5 0.8 6.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAY01593.1 - 2.7e-10 40.0 0.5 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAY01593.1 - 2.6e-08 33.9 3.1 0.00094 19.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAY01593.1 - 8.4e-08 31.7 0.8 8.4e-08 31.7 0.8 2.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EAY01593.1 - 2.1e-06 27.1 3.1 1.4e-05 24.4 1.2 2.6 2 1 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EAY01593.1 - 3.4e-05 23.2 0.5 0.05 12.9 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAY01593.1 - 0.00035 19.9 0.5 0.008 15.4 0.0 2.8 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EAY01593.1 - 0.001 18.4 5.4 0.095 11.9 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EAY01593.1 - 0.0015 17.3 6.6 0.0034 16.2 0.3 3.2 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 EAY01593.1 - 0.0054 15.9 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAY01593.1 - 0.0079 15.8 4.5 0.66 9.5 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase XdhC_C PF13478.6 EAY01593.1 - 0.05 14.1 0.0 5.3 7.6 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain DUF2442 PF10387.9 EAY01593.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) UDPG_MGDP_dh_N PF03721.14 EAY01593.1 - 0.086 12.4 2.5 0.12 11.9 0.5 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 EAY01593.1 - 0.11 11.6 3.9 0.16 11.0 0.4 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EAY01593.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EAY01593.1 - 0.12 12.8 0.6 8.6 6.9 0.1 2.9 3 1 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EAY01593.1 - 0.14 11.5 1.3 1.4 8.3 0.1 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3839 PF12943.7 EAY01596.1 - 9.9e-153 506.5 12.9 1.2e-152 506.2 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY01596.1 - 1.5 9.3 6.0 1.7 9.1 0.2 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Trypan_PARP PF05887.11 EAY01598.1 - 0.032 14.2 8.5 0.051 13.6 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01598.1 - 2.1 8.8 5.6 3 8.3 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY01599.1 - 0.049 14.1 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain L27_1 PF09058.10 EAY01600.1 - 0.01 15.8 3.3 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 L27_1 CREPT PF16566.5 EAY01600.1 - 0.052 13.7 1.0 0.1 12.7 0.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAY01600.1 - 0.091 12.8 0.8 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EAY01600.1 - 1.1 9.4 7.6 0.47 10.6 1.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4107 PF13389.6 EAY01603.1 - 7.1e-74 247.4 4.5 8.4e-74 247.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAY01603.1 - 0.14 10.5 1.0 0.21 10.0 1.0 1.2 1 0 0 1 1 1 0 Lipoxygenase MULE PF10551.9 EAY01604.1 - 1.3e-10 41.6 0.5 1.3e-10 41.6 0.5 1.6 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAY01604.1 - 0.012 14.4 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Oxidored_FMN PF00724.20 EAY01605.1 - 1.4e-51 175.8 0.0 2e-50 172.0 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TAL_FSA PF00923.19 EAY01607.1 - 8.8e-103 343.6 0.2 1e-102 343.4 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Ank PF00023.30 EAY01608.1 - 1.4e-15 56.9 0.3 7e-10 38.9 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAY01608.1 - 1.7e-13 51.0 0.1 4e-13 49.8 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01608.1 - 2.3e-13 50.0 0.0 1.3e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01608.1 - 6.5e-13 48.9 0.0 9.3e-05 22.9 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01608.1 - 4e-10 39.1 0.1 8.9e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EAY01609.1 - 2.6e-14 52.9 0.9 2.6e-14 52.9 0.9 4.1 1 1 3 4 4 4 1 Domain of unknown function (DUF3447) Condensation PF00668.20 EAY01609.1 - 0.023 13.4 1.1 0.031 12.9 1.1 1.2 1 0 0 1 1 1 0 Condensation domain Ribosomal_S28e PF01200.18 EAY01610.1 - 6.2e-31 106.2 2.9 7.1e-31 106.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.18 EAY01611.1 - 6.2e-31 106.2 2.9 7.1e-31 106.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S24e PF01282.19 EAY01612.1 - 3.9e-29 100.4 0.1 6.4e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAY01612.1 - 0.001 18.9 1.2 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Ribosomal_S24e PF01282.19 EAY01613.1 - 3.9e-29 100.4 0.1 6.4e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAY01613.1 - 0.001 18.9 1.2 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Ribosomal_S24e PF01282.19 EAY01614.1 - 3.9e-29 100.4 0.1 6.4e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e UPF0193 PF05250.11 EAY01614.1 - 0.001 18.9 1.2 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) DUF4108 PF13390.6 EAY01615.1 - 6.3e-72 240.2 12.1 7.2e-72 240.0 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Med14 PF08638.11 EAY01616.1 - 0.00053 19.5 2.4 0.0028 17.1 1.3 2.3 2 0 0 2 2 2 1 Mediator complex subunit MED14 Med9 PF07544.13 EAY01616.1 - 0.03 14.4 0.1 0.5 10.5 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ank_2 PF12796.7 EAY01617.1 - 1.6e-43 147.2 26.6 8.5e-17 61.5 6.6 5.2 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01617.1 - 4.7e-42 141.8 25.8 7.6e-12 45.5 0.6 8.0 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EAY01617.1 - 1.8e-41 138.8 19.3 3.3e-07 30.4 0.1 7.7 7 0 0 7 7 7 7 Ankyrin repeat DUF3447 PF11929.8 EAY01617.1 - 2.8e-36 123.3 4.9 2.8e-36 123.3 4.9 5.0 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY01617.1 - 6.8e-32 109.1 20.6 2.9e-08 33.8 0.5 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01617.1 - 5e-31 103.3 22.3 2.6e-05 24.3 0.0 8.4 9 0 0 9 9 9 5 Ankyrin repeat MetallophosN PF16371.5 EAY01617.1 - 0.003 17.8 0.3 25 5.2 0.0 4.1 2 1 3 5 5 5 0 N terminal of Calcineurin-like phosphoesterase RRM_9 PF18444.1 EAY01617.1 - 0.014 15.3 0.4 2.7 7.9 0.0 3.8 3 1 1 4 4 4 0 RNA recognition motif PH_8 PF15409.6 EAY01617.1 - 0.023 14.9 1.1 3 8.2 0.0 4.0 1 1 2 4 4 4 0 Pleckstrin homology domain Arg_repressor PF01316.21 EAY01617.1 - 2.2 8.1 7.4 7.9 6.3 0.0 4.5 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain Methyltransf_8 PF05148.15 EAY01618.1 - 6.1e-74 248.6 0.1 7.6e-74 248.2 0.1 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EAY01618.1 - 6.1e-10 39.6 0.1 2.8e-09 37.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAY01618.1 - 1e-06 29.3 0.1 2e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAY01618.1 - 6.2e-05 22.8 0.3 0.00073 19.4 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAY01618.1 - 0.00028 20.5 0.0 0.44 10.1 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.18 EAY01618.1 - 0.0028 17.0 0.3 0.015 14.6 0.1 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAY01618.1 - 0.0056 17.4 0.4 0.056 14.2 0.1 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 EAY01618.1 - 0.028 13.0 0.0 1.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EAY01618.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Exosortase_EpsH PF09721.10 EAY01618.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) LtuB PF17455.2 EAY01619.1 - 0.0012 19.4 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Late transcription unit B MscS_porin PF12795.7 EAY01619.1 - 0.033 13.8 1.5 0.047 13.2 1.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1843 PF08898.10 EAY01619.1 - 0.18 12.3 1.1 0.57 10.7 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1843) DDE_Tnp_4 PF13359.6 EAY01620.1 - 1.2e-30 106.3 0.0 2.6e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.29 EAY01620.1 - 1.2e-10 41.3 1.6 2.3e-09 37.1 1.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_1 PF01609.21 EAY01620.1 - 4.8e-07 29.7 0.7 2.7e-06 27.2 0.1 2.5 2 1 0 2 2 2 1 Transposase DDE domain UCH_1 PF13423.6 EAY01620.1 - 2.2e-05 24.2 0.6 0.0019 17.9 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAY01620.1 - 0.0057 16.2 2.2 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Fungal_lectin_2 PF18647.1 EAY01620.1 - 0.12 12.8 0.1 0.36 11.3 0.1 1.8 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin ATP-synt_F PF01990.17 EAY01622.1 - 6.3e-33 113.0 0.1 7.2e-33 112.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DrrA_P4M PF14860.6 EAY01622.1 - 0.0031 17.3 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain DUF5588 PF17826.1 EAY01622.1 - 0.16 10.8 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Trehalase_Ca-bi PF07492.11 EAY01623.1 - 0.12 12.2 0.5 0.24 11.2 0.5 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain FKBP_C PF00254.28 EAY01625.1 - 9.1e-32 109.3 0.2 1.5e-31 108.6 0.2 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WBS_methylT PF12589.8 EAY01625.1 - 0.041 14.6 0.7 0.068 13.9 0.7 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome DUF2957 PF11170.8 EAY01625.1 - 0.081 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) PTR2 PF00854.21 EAY01625.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 POT family Dus PF01207.17 EAY01626.1 - 6.8e-51 173.2 0.2 2.4e-50 171.4 0.2 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 EAY01626.1 - 0.001 18.5 0.2 0.0017 17.7 0.2 1.5 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme His_biosynth PF00977.21 EAY01626.1 - 0.0035 16.9 0.1 0.0094 15.4 0.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein CreA PF05981.12 EAY01626.1 - 0.064 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CreA protein Hydrolase_4 PF12146.8 EAY01627.1 - 1.4e-12 47.4 0.0 9.5e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAY01627.1 - 7.1e-08 33.3 0.0 1.6e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAY01627.1 - 9.9e-06 25.4 0.1 6.3e-05 22.7 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EAY01627.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 EAY01627.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAY01627.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase C2 PF00168.30 EAY01628.1 - 1.6e-21 76.5 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EAY01629.1 - 5.4e-21 74.8 9.2 8.2e-11 42.2 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAY01629.1 - 5.3e-19 67.8 10.4 3e-11 43.0 1.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EAY01629.1 - 6.4e-19 66.0 11.8 2.6e-07 29.7 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EAY01629.1 - 3e-16 57.9 7.4 4.3e-07 29.4 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EAY01629.1 - 1.5e-10 40.1 5.7 9e-05 21.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EAY01629.1 - 1.5e-07 31.6 0.3 4.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 EAY01629.1 - 3.3e-06 27.1 1.1 0.71 9.8 0.0 3.2 2 1 1 3 3 3 3 Caleosin related protein DUF3008 PF11450.8 EAY01629.1 - 1.4e-05 25.1 1.3 0.12 12.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknwon function (DUF3008) UPF0154 PF03672.13 EAY01629.1 - 5.4e-05 23.1 0.0 0.0026 17.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF1456 PF07308.13 EAY01629.1 - 0.00022 21.5 1.5 0.038 14.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) SurA_N_2 PF13623.6 EAY01629.1 - 0.00032 20.6 0.3 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 EAY01629.1 - 0.0011 19.3 1.0 1.4 9.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PhetRS_B1 PF18262.1 EAY01629.1 - 0.0054 16.9 0.9 0.2 11.9 0.2 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain FGAR-AT_linker PF18072.1 EAY01629.1 - 0.023 15.2 1.6 55 4.4 0.2 3.6 2 1 2 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_14 PF17959.1 EAY01629.1 - 0.034 14.5 2.1 2.1 8.7 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain EspA PF03433.13 EAY01629.1 - 0.035 14.0 0.1 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 EspA-like secreted protein Armet PF10208.9 EAY01629.1 - 0.045 13.7 1.1 12 5.8 0.1 2.8 1 1 2 3 3 3 0 Degradation arginine-rich protein for mis-folding DUF2789 PF10982.8 EAY01629.1 - 0.053 13.7 0.1 5.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) SurA_N_3 PF13624.6 EAY01629.1 - 0.073 12.8 0.3 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_4 PF12763.7 EAY01629.1 - 0.073 13.0 1.4 9.2 6.3 0.0 2.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Mst1_SARAH PF11629.8 EAY01629.1 - 0.074 13.1 4.1 0.9 9.7 0.1 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 B5 PF03484.15 EAY01629.1 - 0.11 12.9 0.2 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain Peptidase_M24 PF00557.24 EAY01629.1 - 0.17 11.5 0.3 18 5.0 0.0 2.1 2 0 0 2 2 2 0 Metallopeptidase family M24 SCAMP PF04144.13 EAY01630.1 - 3.3e-33 115.5 4.9 4e-33 115.2 4.9 1.1 1 0 0 1 1 1 1 SCAMP family NAD_binding_5 PF07994.12 EAY01631.1 - 1.1e-21 77.5 0.0 1.2e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EAY01631.1 - 8.9e-16 58.1 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ank_4 PF13637.6 EAY01632.1 - 3.8e-54 180.4 13.8 6.6e-15 55.3 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01632.1 - 6e-48 161.3 24.1 4.7e-15 55.9 0.7 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01632.1 - 3.4e-44 147.4 11.2 4.5e-07 30.0 0.9 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 EAY01632.1 - 2e-42 138.3 7.5 3.3e-06 27.0 0.2 6.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EAY01632.1 - 1.5e-27 95.3 16.6 3.4e-10 40.0 0.4 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) RL PF17797.1 EAY01632.1 - 0.0066 16.4 2.8 17 5.4 0.1 3.5 2 1 2 4 4 4 2 RL domain DUF3718 PF12514.8 EAY01632.1 - 0.016 15.3 5.2 44 4.3 0.0 4.9 3 2 2 6 6 6 0 Protein of unknown function (DUF3718) Phage_T7_Capsid PF05396.11 EAY01632.1 - 0.11 12.8 4.3 16 5.9 0.1 3.0 1 1 1 3 3 3 0 Phage T7 capsid assembly protein DUF3447 PF11929.8 EAY01633.1 - 4.4e-39 132.3 4.4 4.4e-39 132.3 4.4 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01633.1 - 6e-31 106.9 8.4 3.3e-15 56.4 1.6 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01633.1 - 8e-31 106.0 3.5 1.2e-12 48.0 0.0 7.2 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY01633.1 - 8.7e-25 86.0 1.1 7.1e-05 23.1 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EAY01633.1 - 2.2e-23 79.8 3.2 0.00015 21.9 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAY01633.1 - 3.9e-22 78.0 4.1 5.7e-09 36.1 0.1 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) zf-C2H2_assoc2 PF16624.5 EAY01635.1 - 0.0029 18.6 1.1 0.0032 18.4 1.1 1.1 1 0 0 1 1 1 1 Unstructured region upstream of a zinc-finger NEMP PF10225.9 EAY01635.1 - 0.53 9.9 1.2 0.57 9.8 1.2 1.0 1 0 0 1 1 1 0 NEMP family NAD_binding_5 PF07994.12 EAY01636.1 - 3.3e-139 463.8 0.0 3.8e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EAY01636.1 - 1.2e-42 144.6 0.1 2e-42 143.8 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FUR PF01475.19 EAY01636.1 - 0.0016 18.6 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 Ferric uptake regulator family MFS_5 PF05631.14 EAY01637.1 - 1.3e-13 50.6 17.1 1.3e-13 50.6 17.1 1.4 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EAY01637.1 - 2.6e-07 29.9 2.5 2.6e-07 29.9 2.5 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Fer2 PF00111.27 EAY01638.1 - 3.9e-07 29.9 0.6 4.7e-07 29.7 0.6 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Robl_LC7 PF03259.17 EAY01639.1 - 1.1e-12 47.6 0.0 1.2e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EAY01639.1 - 0.003 17.5 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 BRE1 PF08647.11 EAY01640.1 - 0.0057 16.7 14.9 0.0057 16.7 14.9 3.1 1 1 2 3 3 3 1 BRE1 E3 ubiquitin ligase DUF2937 PF11157.8 EAY01640.1 - 0.011 15.4 5.6 0.011 15.4 5.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TPR_MLP1_2 PF07926.12 EAY01640.1 - 0.036 14.1 40.6 0.12 12.4 16.1 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Hydrolase_4 PF12146.8 EAY01640.1 - 0.065 12.5 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lebercilin PF15619.6 EAY01640.1 - 0.49 10.0 38.9 1.5e+02 1.9 37.5 3.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease eIF3_subunit PF08597.10 EAY01640.1 - 0.73 9.7 0.0 0.73 9.7 0.0 3.6 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Phage_GP20 PF06810.11 EAY01640.1 - 0.83 9.4 32.7 1.2 8.9 9.3 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 FAM76 PF16046.5 EAY01640.1 - 0.97 8.7 25.0 1.4 8.3 25.0 1.2 1 0 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 EAY01640.1 - 7.9 6.7 38.8 24 5.1 21.5 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Kin17_mid PF10357.9 EAY01641.1 - 2.4e-32 111.5 5.9 3.4e-32 111.0 5.9 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_2 PF12756.7 EAY01641.1 - 0.023 15.0 2.4 0.028 14.8 0.6 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 EAY01641.1 - 0.026 14.7 6.1 0.08 13.2 6.1 2.1 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) MMR_HSR1_C PF08438.10 EAY01641.1 - 0.071 13.7 0.3 0.14 12.7 0.2 1.6 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Crinivirus_P26 PF07416.11 EAY01641.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.5 1 1 1 2 2 2 0 Crinivirus P26 protein zf-met PF12874.7 EAY01641.1 - 0.33 11.4 0.2 0.33 11.4 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ank_4 PF13637.6 EAY01643.1 - 4.3e-37 126.0 2.5 4.7e-10 39.8 0.0 7.1 3 1 4 7 7 7 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01643.1 - 4.7e-36 122.6 7.9 4.7e-36 122.6 7.9 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01643.1 - 8.2e-33 112.9 9.0 3e-14 53.4 1.2 4.3 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01643.1 - 3.2e-28 96.9 1.0 2.2e-06 27.9 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EAY01643.1 - 1.6e-26 89.4 4.9 2.5e-05 24.3 0.1 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAY01643.1 - 8.1e-20 70.6 2.4 1e-07 32.1 0.1 6.4 4 2 3 7 7 7 4 Ankyrin repeats (many copies) DUF1456 PF07308.13 EAY01643.1 - 0.031 14.6 0.1 1.8 9.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) Ank_2 PF12796.7 EAY01644.1 - 1.5e-45 153.7 1.8 2.4e-15 56.9 0.0 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01644.1 - 3.7e-38 129.4 0.1 7.5e-12 45.5 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01644.1 - 2.3e-33 110.4 1.5 4.1e-05 23.6 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EAY01644.1 - 9.8e-30 101.7 0.2 1.6e-05 25.1 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAY01644.1 - 1.1e-25 89.4 0.1 0.00049 20.3 0.0 6.1 1 1 4 6 6 6 5 Ankyrin repeats (many copies) DUF3654 PF12376.8 EAY01644.1 - 0.0053 17.0 0.3 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3654) DUF4316 PF14195.6 EAY01644.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) HALZ PF02183.18 EAY01644.1 - 0.076 13.3 0.7 0.17 12.2 0.7 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper GlgS PF08971.11 EAY01645.1 - 0.014 15.4 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Glycogen synthesis protein Toxin_ToxA PF11584.8 EAY01645.1 - 0.039 14.0 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA Pox_A32 PF04665.12 EAY01646.1 - 6.4e-08 32.4 1.2 7.8e-08 32.1 1.2 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein Zot PF05707.12 EAY01646.1 - 0.0041 16.8 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 EAY01646.1 - 0.046 13.4 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF3783 PF12646.7 EAY01646.1 - 0.069 13.1 0.4 0.62 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) MAT1-1-2 PF17043.5 EAY01647.1 - 0.0036 17.2 0.4 0.0041 17.0 0.4 1.1 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function UBD PF16455.5 EAY01647.1 - 0.11 12.8 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-binding domain DUF3839 PF12943.7 EAY01648.1 - 2.6e-157 521.5 14.3 3.2e-157 521.2 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAY01648.1 - 0.1 12.9 0.5 1.8 8.9 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain KELK PF15796.5 EAY01648.1 - 0.94 10.0 8.4 1.9 9.0 1.1 3.2 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Noelin-1 PF12308.8 EAY01649.1 - 0.095 12.7 4.0 0.28 11.2 4.0 1.8 1 0 0 1 1 1 0 Neurogenesis glycoprotein TMP PF05017.14 EAY01650.1 - 0.12 13.0 7.9 6.3 7.9 0.8 3.4 3 1 0 3 3 3 0 TMP repeat Trypan_PARP PF05887.11 EAY01650.1 - 5.3 7.0 8.4 5.6 6.9 8.4 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_fiss_reg PF05308.11 EAY01651.1 - 0.04 14.0 1.2 0.043 13.9 1.2 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAY01651.1 - 0.58 9.6 5.7 0.6 9.6 5.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rsa3 PF14615.6 EAY01653.1 - 0.042 13.4 0.1 0.088 12.4 0.1 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 MSV199 PF10553.9 EAY01653.1 - 0.13 12.6 9.6 0.15 12.3 9.6 1.1 1 0 0 1 1 1 0 MSV199 domain WXG100 PF06013.12 EAY01653.1 - 0.14 12.4 7.4 1.4 9.2 6.8 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG APG6_N PF17675.1 EAY01653.1 - 0.23 12.0 23.5 0.26 11.8 23.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Tho2 PF11262.8 EAY01653.1 - 0.24 10.6 12.7 0.26 10.4 12.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5401 PF17380.2 EAY01653.1 - 0.44 8.6 15.4 0.45 8.5 15.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3450 PF11932.8 EAY01653.1 - 0.56 9.5 15.7 0.63 9.3 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.6 EAY01653.1 - 0.74 10.2 19.0 7.8 6.9 2.1 3.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 EAY01653.1 - 0.89 7.4 16.2 0.88 7.4 16.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Noelin-1 PF12308.8 EAY01653.1 - 0.94 9.5 8.8 1.1 9.2 8.8 1.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein PCRF PF03462.18 EAY01653.1 - 1.1 9.1 14.1 1.1 9.0 14.1 1.0 1 0 0 1 1 1 0 PCRF domain Med4 PF10018.9 EAY01653.1 - 1.6 8.4 15.2 1.4 8.5 12.8 1.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc24 PF08286.11 EAY01653.1 - 5.6 7.3 18.9 0.82 9.9 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 EAY01653.1 - 8.1 6.5 25.8 2.3 8.3 10.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MRPL52 PF18699.1 EAY01653.1 - 8.6 6.6 17.3 0.86 9.8 11.6 1.9 1 1 1 2 2 2 0 Mitoribosomal protein mL52 PGK PF00162.19 EAY01655.1 - 2.1e-141 471.3 0.5 2.5e-141 471.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Pyr_redox PF00070.27 EAY01655.1 - 0.33 11.5 2.4 35 5.0 0.1 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase V-ATPase_C PF03223.15 EAY01656.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 V-ATPase subunit C WD40 PF00400.32 EAY01658.1 - 1.8e-13 50.7 8.1 1.1e-06 29.2 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY01658.1 - 1.7e-05 25.0 0.1 0.0043 17.3 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EAY01658.1 - 0.0043 16.2 0.4 0.078 12.0 0.4 2.3 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 EAY01658.1 - 0.06 13.2 0.0 5.8 6.8 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAY01658.1 - 0.068 12.1 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_19 PF14559.6 EAY01658.1 - 1.3 9.5 5.4 2.3 8.8 0.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 EAY01659.1 - 2.7e-13 50.3 0.2 1.4e-11 44.8 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01659.1 - 4.2e-11 42.0 0.1 1.2e-05 25.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAY01659.1 - 1.8e-09 37.6 0.0 1.8e-05 24.9 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01659.1 - 5.5e-09 36.4 0.1 1.9e-05 25.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01659.1 - 9.6e-09 35.3 0.5 0.00021 21.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat DHR10 PF18595.1 EAY01659.1 - 0.18 11.9 1.2 0.26 11.3 1.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Myb_DNA-binding PF00249.31 EAY01660.1 - 9.2e-11 41.8 0.1 2e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01660.1 - 1.7e-05 25.0 1.3 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY01660.1 - 0.0052 16.7 0.0 0.0052 16.7 0.0 3.3 3 1 1 4 4 4 1 Myb DNA-binding like CobT PF06213.12 EAY01660.1 - 0.84 9.0 18.6 1.8 7.9 18.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EAY01660.1 - 5 5.8 11.6 8 5.1 11.6 1.3 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EAY01663.1 - 3.3e-15 56.4 0.4 9.7e-08 32.5 0.1 4.1 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01663.1 - 5.1e-05 23.4 1.5 0.47 11.2 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EAY01663.1 - 0.0005 20.3 0.0 0.0076 16.5 0.0 3.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01663.1 - 0.0015 19.0 0.1 0.65 10.6 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY01663.1 - 0.015 15.7 0.7 0.18 12.3 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 EAY01665.1 - 1.3e-13 51.3 0.1 1.6e-06 28.6 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01665.1 - 2.8e-10 40.5 0.5 3.7e-07 30.6 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01665.1 - 3.6e-07 30.0 0.1 7.5 7.5 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EAY01665.1 - 0.0076 16.7 0.0 7.9 7.1 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 EAY01667.1 - 4.1e-05 24.1 0.1 0.0025 18.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01667.1 - 0.011 16.2 0.1 7.1 7.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF1410 PF07198.11 EAY01667.1 - 0.076 13.5 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) Ank_2 PF12796.7 EAY01668.1 - 1.9e-06 28.4 0.2 7.1e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01668.1 - 0.0021 18.6 0.0 0.0052 17.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01668.1 - 0.0062 17.0 0.1 16 6.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EAY01669.1 - 0.051 14.2 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NAPRTase_N PF17767.1 EAY01671.1 - 0.11 12.9 1.7 0.29 11.5 0.4 2.3 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Ank_2 PF12796.7 EAY01673.1 - 1.4e-12 48.0 0.8 1.9e-05 25.1 0.1 4.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01673.1 - 1e-08 35.5 0.2 1.7e-05 25.3 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01673.1 - 8.2e-07 28.9 0.6 6.3 7.7 0.1 5.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAY01673.1 - 0.0034 17.8 2.1 11 6.7 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat YchF-GTPase_C PF06071.13 EAY01673.1 - 0.077 13.2 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Sec7_N PF12783.7 EAY01674.1 - 0.0095 15.9 1.0 0.24 11.3 0.4 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Meckelin PF09773.9 EAY01676.1 - 6.8e-130 434.7 3.8 8.1e-130 434.4 3.8 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) VirE PF05272.11 EAY01679.1 - 1.2e-05 25.2 0.1 1.7e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EAY01679.1 - 0.029 14.7 0.5 0.099 13.0 0.1 2.0 1 1 0 2 2 2 0 RNA helicase DUF4108 PF13390.6 EAY01680.1 - 5.1e-32 110.8 2.2 5.6e-32 110.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) ResIII PF04851.15 EAY01682.1 - 2.2e-05 24.5 0.4 3.5e-05 23.9 0.4 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY01682.1 - 0.0003 20.6 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAY01682.1 - 0.00047 20.4 0.0 0.00069 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAY01682.1 - 0.0022 17.9 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAY01682.1 - 0.0073 16.6 0.0 0.0099 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAY01682.1 - 0.034 13.6 0.0 0.075 12.5 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAY01682.1 - 0.064 13.0 0.0 0.088 12.5 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAY01682.1 - 0.094 12.3 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAY01682.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 EAY01683.1 - 0.031 14.3 8.2 0.04 13.9 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01683.1 - 2.3 8.7 5.3 2.8 8.4 5.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY01684.1 - 0.12 12.8 1.7 0.16 12.4 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Alpha-amylase PF00128.24 EAY01685.1 - 2.2e-05 24.2 0.0 6.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Ecm33 PF12454.8 EAY01685.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LapA_dom PF06305.11 EAY01685.1 - 0.22 11.3 0.2 0.42 10.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amidase02_C PF12123.8 EAY01686.1 - 0.0095 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAY01688.1 - 2.1e-46 158.0 2.1 3.1e-46 157.5 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Glyco_hydro_47 PF01532.20 EAY01690.1 - 3.7e-90 303.0 0.0 4.2e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RuBisCO_large PF00016.20 EAY01690.1 - 0.084 12.1 2.1 0.076 12.2 0.5 1.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Par3_HAL_N_term PF12053.8 EAY01691.1 - 0.17 12.1 1.9 1.2 9.4 0.4 2.2 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins Ank_2 PF12796.7 EAY01693.1 - 1.6e-28 99.1 7.6 3.6e-15 56.3 0.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01693.1 - 1.5e-12 47.8 0.8 3.2e-09 37.1 0.2 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01693.1 - 1.1e-11 43.9 0.7 2.6e-06 27.3 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EAY01693.1 - 2.1e-11 43.8 1.3 2.3e-09 37.3 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01693.1 - 2e-05 24.8 0.1 0.00068 20.0 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EAY01694.1 - 5.3e-10 39.7 0.3 5.1e-08 33.4 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01694.1 - 3.4e-09 37.1 0.1 1.1e-05 25.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01694.1 - 9.4e-08 32.2 0.0 2.8e-05 24.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAY01694.1 - 2.5e-07 30.8 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01694.1 - 3.9e-07 29.8 0.0 0.00022 21.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat BRCT PF00533.26 EAY01694.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CholecysA-Rec_N PF09193.10 EAY01694.1 - 0.14 12.1 0.0 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal WD40_alt PF14077.6 EAY01696.1 - 0.22 11.4 1.9 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif Ank_4 PF13637.6 EAY01699.1 - 1.3e-59 197.9 12.6 2.5e-12 47.0 0.1 10.0 4 1 7 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 EAY01699.1 - 2.5e-57 189.0 11.0 1.6e-07 31.5 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_2 PF12796.7 EAY01699.1 - 1.9e-51 172.6 32.2 9.8e-17 61.3 4.6 6.7 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01699.1 - 3.7e-50 167.3 26.3 2.7e-09 37.1 0.1 6.7 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01699.1 - 5.9e-45 146.1 16.7 2.3e-05 24.4 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat DUF3447 PF11929.8 EAY01699.1 - 1.7e-37 127.2 9.1 1.7e-37 127.2 9.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) RL PF17797.1 EAY01699.1 - 0.00042 20.2 16.2 0.74 9.8 0.5 6.4 4 2 2 7 7 7 2 RL domain DUF2113 PF09886.9 EAY01699.1 - 0.0018 17.7 1.2 0.25 10.7 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2113) RNase_PH_C PF03725.15 EAY01699.1 - 0.0028 17.6 1.7 10 6.2 0.0 4.7 3 2 2 5 5 5 1 3' exoribonuclease family, domain 2 SAB PF04382.13 EAY01699.1 - 0.083 13.0 14.7 55 4.0 0.1 7.4 8 0 0 8 8 8 0 SAB domain Ketoacyl-synt_C PF02801.22 EAY01699.1 - 1.4 8.9 7.6 12 5.9 0.3 3.3 2 1 1 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain TIM21 PF08294.11 EAY01700.1 - 0.085 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 TIM21 SID-1_RNA_chan PF13965.6 EAY01701.1 - 0.00021 19.8 0.2 0.00026 19.6 0.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF31 PF01732.16 EAY01701.1 - 0.005 16.4 3.1 0.0064 16.1 1.9 1.6 2 0 0 2 2 2 1 Putative peptidase (DUF31) Zip PF02535.22 EAY01701.1 - 0.018 14.3 0.4 0.023 13.9 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sigma_reg_N PF13800.6 EAY01701.1 - 0.02 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Tmemb_9 PF05434.11 EAY01701.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.4 1 1 1 2 2 2 0 TMEM9 Tetraspanin PF00335.20 EAY01701.1 - 0.3 10.7 7.4 0.098 12.4 1.0 2.1 1 1 1 2 2 2 0 Tetraspanin family Connexin PF00029.19 EAY01701.1 - 0.42 10.3 3.3 0.71 9.6 3.3 1.4 1 1 0 1 1 1 0 Connexin DUF4834 PF16118.5 EAY01701.1 - 3.6 8.6 10.9 20 6.2 10.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 EAY01701.1 - 8.5 7.1 7.6 4.6e+02 1.5 7.6 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SbsC_C PF18058.1 EAY01702.1 - 0.067 13.4 0.5 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 SbsC C-terminal domain Erf4 PF10256.9 EAY01702.1 - 0.077 13.1 1.1 2.5 8.2 0.1 2.4 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family YlbD_coat PF14071.6 EAY01702.1 - 1.5 9.1 4.7 0.71 10.1 0.5 2.4 2 1 1 3 3 3 0 Putative coat protein Peptidase_A22B PF04258.13 EAY01703.1 - 1.5e-23 83.7 0.6 1.9e-23 83.4 0.6 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EAY01703.1 - 0.014 14.9 2.6 0.032 13.7 2.5 1.5 1 1 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease ThrE_2 PF12821.7 EAY01703.1 - 0.024 14.8 0.6 0.03 14.4 0.6 1.1 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE Ank PF00023.30 EAY01704.1 - 3.4e-09 36.7 0.0 4.3e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAY01704.1 - 6.1e-08 32.8 0.0 1.6e-07 31.5 0.0 1.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY01704.1 - 9.1e-08 32.6 0.0 1.3e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01704.1 - 5.8e-06 26.2 0.0 0.00059 20.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAY01704.1 - 0.0085 16.7 0.0 0.38 11.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TAF6_C PF07571.13 EAY01705.1 - 1.1e-09 38.5 0.0 5e-09 36.4 0.0 2.1 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EAY01705.1 - 3.9e-07 30.1 0.0 7.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF573 PF04504.14 EAY01705.1 - 0.11 13.1 0.4 20 5.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Glyco_transf_10 PF00852.19 EAY01705.1 - 0.12 12.1 0.2 0.29 10.8 0.2 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term TMC PF07810.13 EAY01706.1 - 0.039 14.5 0.6 0.039 14.5 0.6 3.5 3 1 0 3 3 3 0 TMC domain MatE PF01554.18 EAY01707.1 - 6.1e-27 94.2 23.2 1.1e-13 51.2 0.9 2.5 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EAY01707.1 - 0.00079 19.5 6.7 0.00079 19.5 6.7 3.9 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Trypan_PARP PF05887.11 EAY01708.1 - 0.07 13.1 10.3 0.1 12.6 10.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDR PF08841.10 EAY01709.1 - 0.087 11.8 0.1 0.082 11.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain PWI PF01480.17 EAY01711.1 - 9.6e-08 32.2 0.2 1.7e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 PWI domain SR-25 PF10500.9 EAY01711.1 - 0.038 13.6 24.0 0.11 12.1 10.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SnAC PF14619.6 EAY01711.1 - 0.16 12.6 1.5 0.22 12.1 0.1 2.0 2 1 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex DUF755 PF05501.11 EAY01711.1 - 0.44 10.8 30.8 2.1 8.6 9.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IMUP PF15761.5 EAY01711.1 - 4.1 8.1 25.2 1.4 9.7 7.5 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Chorion_2 PF03964.15 EAY01711.1 - 7.3 7.5 17.9 4.5 8.2 8.3 2.2 2 0 0 2 2 2 0 Chorion family 2 IBD PF10416.9 EAY01712.1 - 2.6e-36 124.5 1.1 3.5e-36 124.0 1.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Peptidase_M24 PF00557.24 EAY01713.1 - 1e-39 136.4 0.0 1.4e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Myb_DNA-binding PF00249.31 EAY01714.1 - 1e-29 102.5 1.4 2.8e-14 53.0 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01714.1 - 4.4e-22 78.1 1.4 1.5e-11 44.4 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY01714.1 - 0.0029 17.6 0.1 1.3 9.1 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY01714.1 - 0.012 15.5 0.7 0.12 12.2 0.1 2.4 1 1 1 2 2 2 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EAY01714.1 - 0.016 15.5 0.6 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 EAY01714.1 - 0.05 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Ank_2 PF12796.7 EAY01715.1 - 6.2e-14 52.3 2.1 4.1e-05 24.1 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY01715.1 - 7.7e-13 48.2 6.4 7.7e-13 48.2 6.4 4.8 3 1 3 6 6 6 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY01715.1 - 4.7e-09 36.3 0.0 0.00029 21.1 0.0 4.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01715.1 - 1.7e-08 34.1 0.4 0.41 11.4 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EAY01715.1 - 4.3e-08 33.5 0.2 0.0052 17.3 0.0 4.8 5 2 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY01715.1 - 6.8e-07 29.5 0.0 0.035 14.6 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Tnp_22_dsRBD PF17490.2 EAY01715.1 - 0.081 12.9 0.3 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 L1 transposable element dsRBD-like domain ANAPC4_WD40 PF12894.7 EAY01716.1 - 5.7e-06 26.5 0.0 0.21 11.9 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EAY01716.1 - 0.0006 19.8 0.4 4.2 7.5 0.1 4.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EAY01716.1 - 0.002 18.9 7.4 3.8 8.5 0.0 6.5 8 0 0 8 8 8 2 WD domain, G-beta repeat VPS9 PF02204.18 EAY01716.1 - 0.056 13.7 0.1 0.32 11.3 0.1 2.3 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain S-AdoMet_synt_C PF02773.16 EAY01718.1 - 1.8e-68 228.8 0.0 7.9e-68 226.7 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAY01718.1 - 1e-44 151.6 0.0 1.8e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAY01718.1 - 1.3e-42 144.5 0.5 1.3e-42 144.5 0.5 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EAY01718.1 - 0.014 14.2 1.3 2.6 6.8 0.1 2.1 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) MCPsignal PF00015.21 EAY01718.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SesA PF17107.5 EAY01719.1 - 0.023 14.9 1.4 0.056 13.6 0.5 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Bcr-Abl_Oligo PF09036.10 EAY01719.1 - 0.066 13.2 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4106 PF13388.6 EAY01720.1 - 1.4e-124 416.5 32.2 1.4e-124 416.5 32.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF4106) KAR PF15222.6 EAY01720.1 - 0.035 14.4 2.4 0.9 9.9 0.1 3.2 3 0 0 3 3 3 0 Kidney androgen-regulated Big_8 PF17961.1 EAY01721.1 - 0.024 14.7 0.3 0.06 13.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig domain B3R PF17057.5 EAY01721.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxviridae B3 protein SH3_5 PF08460.10 EAY01721.1 - 0.059 13.5 0.1 0.61 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain Bromodomain PF00439.25 EAY01722.1 - 3.1e-21 75.2 0.7 7.6e-21 74.0 0.1 1.8 2 1 0 2 2 2 1 Bromodomain RhoGEF PF00621.20 EAY01723.1 - 1.1e-30 107.2 0.9 2.3e-30 106.2 0.9 1.5 1 0 0 1 1 1 1 RhoGEF domain Fibrinogen_BP PF08017.11 EAY01723.1 - 0.039 12.4 0.0 0.077 11.4 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen binding protein ProRS-C_2 PF09181.10 EAY01724.1 - 0.085 13.0 0.4 0.3 11.2 0.4 2.0 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal RRM_1 PF00076.22 EAY01727.1 - 5.7e-07 29.3 0.1 0.021 14.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.6 EAY01728.1 - 0.0094 16.5 0.0 0.0098 16.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAY01728.1 - 0.024 15.1 0.1 0.96 10.0 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ufm1 PF03671.14 EAY01728.1 - 0.041 14.0 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Ank_5 PF13857.6 EAY01728.1 - 0.051 13.9 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Isochorismatase PF00857.20 EAY01729.1 - 0.045 13.9 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Isochorismatase family RWD PF05773.22 EAY01730.1 - 0.067 13.5 0.0 0.097 13.0 0.0 1.4 1 1 0 1 1 1 0 RWD domain DUF2040 PF09745.9 EAY01730.1 - 0.084 12.9 0.6 0.15 12.1 0.2 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) GCR1_C PF12550.8 EAY01730.1 - 0.12 12.8 0.4 0.2 12.0 0.4 1.4 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.25 EAY01731.1 - 1.6e-71 240.8 0.0 2.1e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01731.1 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01731.1 - 4.9e-05 22.8 0.0 0.00015 21.2 0.0 1.8 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EAY01731.1 - 0.0032 16.5 0.0 0.0051 15.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAY01731.1 - 0.0069 16.3 0.0 0.065 13.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAY01731.1 - 0.0087 15.4 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAY01731.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAY01731.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_C48 PF02902.19 EAY01734.1 - 1.6e-05 24.9 0.4 2.3e-05 24.3 0.4 1.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FeoB_associated PF12669.7 EAY01735.1 - 9.8 6.7 7.4 0.98 9.9 2.3 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Beta_helix PF13229.6 EAY01736.1 - 0.018 14.9 3.8 0.028 14.3 3.8 1.3 1 0 0 1 1 1 0 Right handed beta helix region Chlam_PMP PF02415.17 EAY01736.1 - 0.32 11.6 3.1 15 6.3 0.5 2.7 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sec1 PF00995.23 EAY01737.1 - 6.9e-50 170.8 0.0 1e-49 170.3 0.0 1.2 1 0 0 1 1 1 1 Sec1 family RabGAP-TBC PF00566.18 EAY01739.1 - 2.9e-22 79.4 12.3 5.5e-22 78.5 7.4 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GDE_C PF06202.14 EAY01740.1 - 0.0063 15.5 0.1 0.0066 15.4 0.1 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Pkinase PF00069.25 EAY01741.1 - 9.1e-53 179.3 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01741.1 - 1.8e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01741.1 - 2.2e-08 33.8 0.0 6.6e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAY01741.1 - 0.0023 17.1 0.1 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAY01741.1 - 0.0061 15.4 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY01741.1 - 0.05 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IF4E PF01652.18 EAY01742.1 - 4.8e-37 127.2 0.8 5.7e-37 127.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Gly-zipper_Omp PF13488.6 EAY01746.1 - 0.0075 16.2 9.0 0.0075 16.2 9.0 1.5 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 EAY01746.1 - 0.25 11.6 4.8 0.37 11.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY01746.1 - 0.92 9.6 5.4 1.1 9.4 4.8 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAY01748.1 - 5.8e-05 22.7 2.2 6.7e-05 22.5 1.4 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY01748.1 - 0.0068 16.4 0.5 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Y_phosphatase2 PF03162.13 EAY01748.1 - 0.023 14.3 0.2 0.047 13.3 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_trans_1_3 PF13528.6 EAY01748.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF3839 PF12943.7 EAY01750.1 - 1.1e-156 519.4 13.9 1.4e-156 519.1 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) MitMem_reg PF13012.6 EAY01750.1 - 0.1 13.0 0.2 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KELK PF15796.5 EAY01750.1 - 2.1 8.9 8.6 1.4 9.4 0.6 3.4 3 2 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PTR PF12789.7 EAY01751.1 - 1.4e-22 79.5 20.8 9.4e-17 60.8 1.5 4.7 6 0 0 6 6 6 2 Phage tail repeat like DUF240 PF03086.14 EAY01751.1 - 0.054 13.4 2.7 1.7 8.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF1493 PF07377.12 EAY01752.1 - 0.05 14.1 0.9 0.1 13.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY01753.1 - 0.027 15.0 2.7 11 7.2 0.2 2.9 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY01754.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP DUF3447 PF11929.8 EAY01755.1 - 6.3e-18 64.5 5.4 6.3e-18 64.5 5.4 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01755.1 - 1.3e-05 25.7 0.7 0.012 16.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01755.1 - 4.9e-05 23.5 0.1 0.00028 21.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01755.1 - 0.0022 18.3 5.5 0.18 12.5 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EAY01755.1 - 0.0029 18.1 1.9 1.6 9.4 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAY01757.1 - 0.042 13.8 6.2 0.23 11.4 0.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EAY01757.1 - 0.062 13.6 0.1 0.57 10.6 0.2 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Endothelin PF00322.17 EAY01757.1 - 0.1 12.2 0.8 0.22 11.1 0.8 1.5 1 0 0 1 1 1 0 Endothelin family Ank_2 PF12796.7 EAY01757.1 - 0.14 12.8 0.1 0.31 11.6 0.1 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) HTH_18 PF12833.7 EAY01758.1 - 0.026 14.8 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ING PF12998.7 EAY01759.1 - 0.0045 17.5 0.1 0.0093 16.5 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding NPV_P10 PF05531.12 EAY01759.1 - 0.095 13.2 1.2 0.11 13.0 0.2 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein VitK2_biosynth PF02621.14 EAY01761.1 - 0.053 13.0 0.8 0.056 13.0 0.8 1.0 1 0 0 1 1 1 0 Menaquinone biosynthesis FH2 PF02181.23 EAY01761.1 - 0.061 12.4 0.6 0.067 12.3 0.6 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain MSA-2c PF12238.8 EAY01761.1 - 0.2 11.7 0.6 0.2 11.6 0.6 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c CCDC-167 PF15188.6 EAY01764.1 - 0.0047 17.2 0.1 0.0054 17.0 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 CorA PF01544.18 EAY01764.1 - 0.035 13.4 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF919 PF06034.11 EAY01765.1 - 0.062 13.2 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Rpn9_C PF18261.1 EAY01768.1 - 2.3 7.9 8.8 0.1 12.2 3.1 1.7 2 0 0 2 2 2 0 Rpn9 C-terminal helix Collagen_bind_2 PF12904.7 EAY01770.1 - 0.13 12.3 0.0 4.6 7.3 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAY01771.1 - 1.2e-70 236.9 4.4 1.7e-70 236.3 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAY01771.1 - 0.066 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAY01772.1 - 0.0019 17.9 0.0 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF1731 PF08338.11 EAY01772.1 - 0.15 11.9 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PTR PF12789.7 EAY01774.1 - 2.6e-09 37.0 11.7 1.1e-08 35.0 5.2 5.8 6 1 0 6 6 6 3 Phage tail repeat like LIFR_D2 PF17971.1 EAY01774.1 - 0.004 17.3 0.3 0.7 10.1 0.0 2.4 2 0 0 2 2 2 2 Leukemia inhibitory factor receptor D2 domain DUF1910 PF08928.10 EAY01774.1 - 0.044 13.8 0.3 4.5 7.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) IL2 PF00715.17 EAY01774.1 - 0.33 10.9 4.3 7.4 6.5 0.1 2.6 3 0 0 3 3 3 0 Interleukin 2 DNA_pol_B_2 PF03175.13 EAY01775.1 - 2.6e-09 36.5 0.8 5.4e-09 35.4 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAY01775.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAY01776.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAY01776.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2939 PF11159.8 EAY01777.1 - 0.017 15.5 0.5 0.023 15.1 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY01777.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAS_N PF17828.1 EAY01778.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta GPS2_interact PF15784.5 EAY01780.1 - 0.025 15.0 1.3 0.035 14.5 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain SPT16 PF08644.11 EAY01782.1 - 0.04 14.1 4.6 0.048 13.8 4.6 1.3 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) PAP2 PF01569.21 EAY01783.1 - 1.7e-28 99.1 3.3 3.4e-27 94.9 0.5 2.2 2 0 0 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.6 EAY01783.1 - 0.0013 18.5 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EAY01783.1 - 0.0054 17.2 2.8 0.0054 17.2 2.8 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal RRM_1 PF00076.22 EAY01785.1 - 2.7e-06 27.1 0.0 6.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.22 EAY01786.1 - 8.4e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2635 PF10948.8 EAY01786.1 - 0.089 12.5 0.3 0.64 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) RTTN_N PF14726.6 EAY01787.1 - 0.017 15.9 5.2 0.042 14.6 0.5 3.1 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Prp18 PF02840.15 EAY01787.1 - 0.084 12.9 0.5 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Prp18 domain DUF4309 PF14172.6 EAY01789.1 - 0.26 11.3 5.1 0.16 12.0 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) DUF2884 PF11101.8 EAY01790.1 - 0.037 13.5 1.2 0.059 12.9 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Ku_PK_bind PF08785.11 EAY01790.1 - 0.047 13.8 0.7 0.076 13.2 0.4 1.6 2 0 0 2 2 2 0 Ku C terminal domain like MORN PF02493.20 EAY01791.1 - 2.3e-08 33.5 5.9 0.0066 16.3 0.3 3.5 3 0 0 3 3 3 3 MORN repeat STAG PF08514.11 EAY01792.1 - 4.2e-05 23.4 3.3 5e-05 23.2 0.9 2.4 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 EAY01792.1 - 0.0015 18.6 3.6 11 6.5 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EAY01792.1 - 0.0019 18.5 0.0 8.9 6.8 0.0 3.7 3 1 2 5 5 5 2 HEAT repeats DCB PF16213.5 EAY01792.1 - 0.013 15.1 6.2 0.028 14.1 0.5 3.1 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF4363 PF14276.6 EAY01792.1 - 0.047 13.8 0.0 0.047 13.8 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) Vac14_Fab1_bd PF12755.7 EAY01792.1 - 0.17 12.5 6.9 2.7 8.6 0.2 4.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region BTB PF00651.31 EAY01793.1 - 5.2e-13 49.2 5.4 5.6e-13 49.1 0.6 2.5 2 0 0 2 2 2 1 BTB/POZ domain CybS PF05328.12 EAY01793.1 - 0.0069 16.1 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF2963 PF11178.8 EAY01793.1 - 0.025 14.3 0.5 13 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) His_Phos_2 PF00328.22 EAY01793.1 - 0.042 13.2 1.4 0.057 12.8 1.4 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ribosomal_S25 PF03297.15 EAY01794.1 - 3.1e-17 62.6 0.2 3.1e-17 62.6 0.2 1.9 2 0 0 2 2 2 1 S25 ribosomal protein GntR PF00392.21 EAY01794.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 EAY01794.1 - 0.00087 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EAY01794.1 - 0.0071 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EAY01794.1 - 0.032 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator EAP30 PF04157.16 EAY01794.1 - 0.04 13.2 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family FeoC PF09012.10 EAY01794.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Myb_DNA-binding PF00249.31 EAY01795.1 - 2.9e-25 88.2 2.6 6.9e-14 51.8 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01795.1 - 3e-24 85.0 2.5 3.8e-14 52.7 0.8 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY01795.1 - 0.019 14.8 0.2 0.33 10.9 0.0 2.3 2 1 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.8 EAY01795.1 - 0.17 12.0 0.4 0.62 10.2 0.4 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAY01795.1 - 0.21 12.0 4.6 0.64 10.4 1.1 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain CS PF04969.16 EAY01796.1 - 8.4e-10 39.5 2.2 1.6e-09 38.6 2.2 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EAY01796.1 - 3.3e-09 36.2 0.1 0.0012 18.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAY01796.1 - 1.6e-08 34.6 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_1 PF00515.28 EAY01796.1 - 2.3e-08 33.5 1.5 0.00068 19.4 1.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAY01796.1 - 3.4e-08 33.6 0.2 2.6e-07 30.8 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAY01796.1 - 7.8e-05 22.9 0.3 0.43 10.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAY01796.1 - 9.2e-05 22.8 0.2 0.13 13.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAY01796.1 - 0.0003 21.4 0.0 0.014 16.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAY01796.1 - 0.0012 18.9 0.8 0.035 14.3 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAY01796.1 - 0.0039 17.7 0.2 0.13 12.8 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAY01796.1 - 0.015 16.1 0.0 0.6 11.1 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAY01796.1 - 0.03 14.3 0.3 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAY01796.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SHS2_Rpb7-N PF03876.17 EAY01797.1 - 2.3e-09 37.5 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Rep_N PF08724.10 EAY01798.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Rep protein catalytic domain like GxDLY PF14607.6 EAY01798.1 - 0.078 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type DUF4392 PF14336.6 EAY01799.1 - 5.5e-35 121.2 0.0 2.5e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4392) SCAMP PF04144.13 EAY01800.1 - 4.7e-34 118.2 8.3 5.4e-34 118.0 8.3 1.0 1 0 0 1 1 1 1 SCAMP family TssN PF17555.2 EAY01800.1 - 0.0003 20.3 2.2 0.00041 19.8 2.2 1.2 1 0 0 1 1 1 1 Type VI secretion system, TssN MpPF26 PF07666.11 EAY01800.1 - 0.12 12.5 3.4 0.33 11.1 3.4 1.7 1 1 0 1 1 1 0 M penetrans paralogue family 26 Caveolin PF01146.17 EAY01800.1 - 0.27 11.2 2.3 0.22 11.5 0.4 1.8 2 1 0 2 2 2 0 Caveolin MCM PF00493.23 EAY01801.1 - 4.4e-91 303.9 0.0 6.8e-91 303.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAY01801.1 - 6.2e-31 106.9 0.0 1.6e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAY01801.1 - 1.7e-22 79.6 0.2 4.9e-22 78.2 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAY01801.1 - 2.1e-10 41.1 0.1 6.3e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAY01801.1 - 2.5e-08 33.5 0.2 3e-06 26.8 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI HPD PF05044.12 EAY01801.1 - 0.021 14.7 0.5 0.064 13.1 0.5 1.7 1 0 0 1 1 1 0 Homeo-prospero domain AAA_5 PF07728.14 EAY01801.1 - 0.026 14.5 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAY01801.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 EAY01801.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin DUF3527 PF12043.8 EAY01801.1 - 0.057 13.0 4.3 0.1 12.2 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Sigma54_activat PF00158.26 EAY01801.1 - 0.058 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EAY01801.1 - 0.16 12.4 0.6 5.1 7.5 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IZUMO PF15005.6 EAY01801.1 - 0.27 11.8 2.9 1.6 9.2 0.2 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Rtf2 PF04641.12 EAY01801.1 - 0.98 8.7 11.5 1.7 7.9 11.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 EAY01801.1 - 5.1 5.7 7.3 7.4 5.2 7.3 1.1 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EAY01802.1 - 5.6e-16 58.9 0.0 1.2e-06 29.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01802.1 - 8.1e-13 47.3 0.1 0.00026 21.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAY01802.1 - 1.3e-11 44.4 0.1 5.9e-05 23.3 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAY01802.1 - 2.2e-10 40.8 0.1 1.1e-06 29.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01802.1 - 4.5e-10 39.6 0.1 0.0019 18.4 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) L_protein_N PF15518.6 EAY01802.1 - 0.018 14.8 0.0 0.04 13.8 0.0 1.7 1 1 0 1 1 1 0 L protein N-terminus DUF3083 PF11281.8 EAY01802.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3083) Amidase02_C PF12123.8 EAY01803.1 - 0.0037 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAY01804.1 - 6.1e-71 237.8 4.1 8.2e-71 237.4 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Chal_sti_synt_N PF00195.19 EAY01805.1 - 0.031 13.7 0.7 0.06 12.8 0.7 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain EssA PF10661.9 EAY01805.1 - 2.8 7.8 8.3 7.7 6.3 8.3 1.7 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA TPR_MLP1_2 PF07926.12 EAY01806.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaRep2a PF07903.11 EAY01806.1 - 0.06 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein Spo12 PF05032.12 EAY01806.1 - 0.45 10.5 8.3 0.16 11.9 2.9 2.4 3 0 0 3 3 3 0 Spo12 family PAS_9 PF13426.7 EAY01808.1 - 0.014 15.6 1.5 0.11 12.8 0.7 2.9 3 0 0 3 3 3 0 PAS domain DUF2439 PF10382.9 EAY01808.1 - 0.42 11.0 4.2 0.67 10.3 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2439) DUF5305 PF17231.2 EAY01810.1 - 0.0051 16.2 1.3 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5305) DUF5326 PF17260.2 EAY01810.1 - 0.0089 16.1 0.4 0.013 15.6 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5326) Mid2 PF04478.12 EAY01810.1 - 0.013 15.4 0.8 0.017 15.0 0.1 1.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 EAY01810.1 - 0.016 16.0 1.0 0.035 15.0 0.0 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 EAY01810.1 - 0.019 14.5 0.8 0.028 14.0 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Syndecan PF01034.20 EAY01810.1 - 0.97 9.4 5.1 2.7 8.0 5.1 1.7 1 1 0 1 1 1 0 Syndecan domain Bac_A_amyl_C PF18612.1 EAY01811.1 - 0.01 15.6 2.1 0.72 9.7 0.2 2.7 2 1 1 3 3 3 0 Bacterial Alpha amylase C-terminal domain PI3K_p85B PF02192.16 EAY01811.1 - 0.065 13.0 0.6 0.71 9.6 0.3 2.4 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain DUF4923 PF16270.5 EAY01812.1 - 0.062 13.1 0.6 0.22 11.3 0.6 1.9 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) ETRAMP PF09716.10 EAY01814.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.6 4 1 1 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) LPAM_2 PF13627.6 EAY01814.1 - 1.9 8.5 5.0 4.8 7.1 5.0 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Alpha-amylase PF00128.24 EAY01815.1 - 3e-47 161.8 4.0 2.2e-27 96.5 0.8 3.0 1 1 2 3 3 3 2 Alpha amylase, catalytic domain UBA_6 PF18039.1 EAY01816.1 - 0.035 14.0 0.8 0.074 13.0 0.1 1.9 2 0 0 2 2 2 0 UBA-like domain ubiquitin PF00240.23 EAY01816.1 - 0.04 13.7 0.2 0.098 12.4 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin family Guanylate_cyc PF00211.20 EAY01817.1 - 4.7e-47 160.0 0.1 7.8e-47 159.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY01817.1 - 1.9e-14 53.8 0.4 2.5e-13 50.2 0.4 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAY01817.1 - 2.7e-06 27.4 0.1 8.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 EAY01817.1 - 0.0036 16.8 0.1 0.0071 15.8 0.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated PWI PF01480.17 EAY01818.1 - 0.017 15.4 1.0 2.7 8.4 0.0 3.3 3 0 0 3 3 3 0 PWI domain DUF2205 PF10224.9 EAY01818.1 - 0.053 13.5 2.3 8.2 6.5 0.2 2.7 2 0 0 2 2 2 0 Short coiled-coil protein Pkinase PF00069.25 EAY01821.1 - 8.8e-50 169.5 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01821.1 - 4.6e-29 101.5 0.0 5.8e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01821.1 - 0.0018 17.6 0.0 0.0054 16.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Myb_DNA-binding PF00249.31 EAY01822.1 - 3.9e-28 97.4 1.3 1.9e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01822.1 - 1.2e-18 67.1 4.8 4e-14 52.6 1.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY01822.1 - 7.5e-08 32.4 0.4 0.0097 15.9 0.1 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY01822.1 - 0.0037 17.1 3.4 0.76 9.7 0.2 2.4 2 0 0 2 2 2 2 Myb DNA-binding like H-kinase_dim PF02895.14 EAY01822.1 - 0.0061 16.9 0.4 0.018 15.4 0.1 2.0 2 0 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain PriA_C PF18074.1 EAY01822.1 - 0.17 12.7 1.4 1.7 9.5 0.3 2.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain FPRL1_inhibitor PF16104.5 EAY01822.1 - 0.19 11.9 2.6 23 5.2 0.0 3.1 2 2 1 3 3 3 0 Formyl peptide receptor-like 1 inhibitory protein SANT_DAMP1_like PF16282.5 EAY01822.1 - 0.3 11.3 3.6 6.8 7.0 0.1 3.0 4 0 0 4 4 4 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 EAY01823.1 - 5.3e-30 103.3 0.7 9.5e-15 54.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01823.1 - 1.3e-20 73.4 1.2 3.9e-14 52.6 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY01823.1 - 9.1e-09 35.3 0.0 0.00074 19.5 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EAY01823.1 - 0.018 14.9 0.2 3.3 7.7 0.1 2.3 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EAY01823.1 - 0.3 11.5 3.2 3.2 8.2 0.2 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EAY01824.1 - 5.7e-30 103.2 0.6 3e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01824.1 - 2.6e-18 66.0 0.4 1.5e-12 47.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY01824.1 - 7.4e-07 29.2 0.1 0.00078 19.5 0.0 2.6 1 1 2 3 3 3 2 SLIDE WH2 PF02205.20 EAY01824.1 - 7 6.6 7.3 24 5.0 0.1 3.5 4 0 0 4 4 4 0 WH2 motif HAD_2 PF13419.6 EAY01826.1 - 7.1e-28 97.9 0.0 9.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAY01826.1 - 1.2e-17 64.9 0.1 3.2e-16 60.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAY01826.1 - 2e-08 34.9 0.0 2.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAY01826.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAY01826.1 - 0.0023 18.0 0.0 0.019 15.1 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAY01826.1 - 0.0057 16.4 0.3 3.3 7.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase 6PGD PF00393.19 EAY01827.1 - 1.7e-114 382.1 0.1 2.1e-114 381.8 0.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAY01827.1 - 8.6e-44 149.5 0.0 1.4e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAY01827.1 - 5.1e-08 33.4 0.0 1.3e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EAY01827.1 - 8.4e-07 28.7 0.4 4.2e-05 23.2 0.1 2.7 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EAY01827.1 - 9.8e-07 28.8 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EAY01827.1 - 7.5e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EAY01827.1 - 8.8e-05 21.9 0.8 0.0003 20.2 0.0 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EAY01827.1 - 0.00063 19.7 0.8 0.0039 17.2 0.3 2.4 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EAY01827.1 - 0.0014 18.7 0.6 0.0073 16.4 0.1 2.2 2 1 1 3 3 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EAY01827.1 - 0.0019 17.8 0.5 0.0093 15.6 0.9 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EAY01827.1 - 0.002 18.4 0.1 0.0043 17.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EAY01827.1 - 0.0045 16.3 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PDH PF02153.17 EAY01827.1 - 0.0083 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase UDPG_MGDP_dh_C PF03720.15 EAY01827.1 - 0.012 16.0 0.1 0.045 14.2 0.0 1.9 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Pyr_redox_2 PF07992.14 EAY01827.1 - 0.027 13.7 0.0 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 7kD_DNA_binding PF02294.18 EAY01827.1 - 0.09 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 7kD DNA-binding domain ADH_zinc_N PF00107.26 EAY01827.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IlvN PF07991.12 EAY01827.1 - 0.17 11.5 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gly_rich PF12810.7 EAY01830.1 - 1e-23 84.5 44.4 1.4e-23 84.1 44.4 1.1 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAY01831.1 - 9.1e-26 90.3 9.2 1.6e-14 54.0 0.1 2.4 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01831.1 - 7.5e-11 41.6 0.0 1.6e-05 24.6 0.0 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EAY01831.1 - 0.0026 18.1 3.5 5.1 7.6 0.2 5.3 2 2 4 6 6 6 2 Leucine Rich repeats (2 copies) DUF1751 PF08551.10 EAY01832.1 - 4.9e-13 49.5 2.0 4.9e-13 49.5 2.0 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EAY01832.1 - 0.0052 16.8 2.5 0.0083 16.1 2.5 1.3 1 0 0 1 1 1 1 Rhomboid family DUF3083 PF11281.8 EAY01833.1 - 0.021 14.2 0.3 0.022 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Sec23_BS PF08033.12 EAY01834.1 - 0.0094 16.7 0.1 0.029 15.1 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain CsgA PF17334.2 EAY01834.1 - 0.53 11.1 4.8 0.7 10.7 0.1 2.9 3 0 0 3 3 3 0 Minor curli fiber component A C2 PF00168.30 EAY01835.1 - 1.7e-21 76.4 0.1 2.3e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain PAP2 PF01569.21 EAY01836.1 - 4.1e-16 59.0 1.3 4.1e-16 59.0 1.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EAY01836.1 - 0.001 19.6 0.2 0.001 19.6 0.2 2.8 3 1 0 3 3 3 1 PAP2 superfamily C-terminal DHHC PF01529.20 EAY01836.1 - 7.4 6.7 9.4 0.95 9.6 3.9 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase WD40 PF00400.32 EAY01837.1 - 2.9e-49 164.0 25.1 7.1e-10 39.3 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY01837.1 - 9.3e-25 86.8 0.3 0.0033 17.7 0.0 6.4 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAY01837.1 - 4.2e-11 43.1 0.4 8e-07 29.1 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EAY01837.1 - 4.8e-06 26.3 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 EAY01837.1 - 0.00025 20.1 0.2 3.7 6.4 0.0 3.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EAY01837.1 - 0.00045 19.6 0.1 1.3 8.3 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 EAY01837.1 - 0.015 15.3 0.0 1.2e+02 2.8 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EAY01837.1 - 0.024 12.7 1.0 0.2 9.6 0.1 2.5 2 1 0 3 3 3 0 IKI3 family RCC1 PF00415.18 EAY01838.1 - 9.3e-18 64.6 1.9 8.2e-08 32.8 0.1 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAY01838.1 - 1.4e-09 37.5 5.4 3.1e-07 30.0 2.1 4.5 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 EAY01839.1 - 1.9e-46 155.7 0.1 6.1e-15 54.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAY01839.1 - 2e-14 53.2 0.0 0.0027 17.3 0.0 3.1 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAY01839.1 - 1.9e-09 37.2 0.0 9.3e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EAY01839.1 - 1.5e-08 34.6 0.1 0.33 11.0 0.0 3.5 3 0 0 3 3 3 3 Limkain b1 RRM_3 PF08777.11 EAY01839.1 - 1.7e-06 28.0 0.0 0.051 13.6 0.0 2.4 1 1 1 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 EAY01839.1 - 3.9e-05 23.6 0.1 0.3 11.1 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 EAY01839.1 - 0.067 13.2 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain WD40 PF00400.32 EAY01840.1 - 2.2e-13 50.4 6.0 3.5e-05 24.5 0.5 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY01840.1 - 6.3e-13 48.8 0.1 0.002 18.4 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAY01840.1 - 0.0017 17.8 0.4 3.8 6.7 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain TIMP PF00965.17 EAY01840.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF5449 PF17528.2 EAY01840.1 - 0.048 13.4 0.0 2.4 7.9 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5449) Ricin_B_lectin PF00652.22 EAY01840.1 - 0.082 13.2 1.2 17 5.7 0.2 3.0 2 2 0 2 2 2 0 Ricin-type beta-trefoil lectin domain RasGEF PF00617.19 EAY01841.1 - 1.3e-10 41.8 1.2 2.5e-10 40.8 0.4 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EAY01841.1 - 0.00015 22.0 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif MMPL PF03176.15 EAY01843.1 - 0.0099 14.8 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 1 MMPL family Prominin PF05478.11 EAY01843.1 - 0.11 10.5 5.1 0.13 10.2 5.1 1.1 1 0 0 1 1 1 0 Prominin FAM163 PF15069.6 EAY01843.1 - 0.8 10.1 10.6 1.4 9.4 9.6 1.9 2 0 0 2 2 2 0 FAM163 family DNA_pol3_beta_2 PF02767.16 EAY01844.1 - 0.018 15.2 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Claudin_2 PF13903.6 EAY01844.1 - 0.035 13.9 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FlaC_arch PF05377.11 EAY01844.1 - 0.036 14.5 1.4 0.036 14.5 1.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LRR_5 PF13306.6 EAY01845.1 - 1.9e-57 192.8 52.6 3.5e-25 88.4 18.2 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01845.1 - 0.0049 16.6 1.7 0.87 9.4 0.1 4.1 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EAY01845.1 - 0.058 13.8 1.7 4.4 7.9 0.5 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DDR PF08841.10 EAY01846.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Trypan_PARP PF05887.11 EAY01847.1 - 0.08 12.9 7.2 0.12 12.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAS_N PF17828.1 EAY01848.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAY01849.1 - 0.016 15.6 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) PapD_N PF00345.20 EAY01850.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF2400 PF09674.10 EAY01850.1 - 0.079 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EAY01850.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) KilA-N PF04383.13 EAY01851.1 - 8.1e-43 144.8 0.3 2.3e-42 143.4 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain DUF3839 PF12943.7 EAY01852.1 - 2.8e-25 89.2 4.5 4.3e-25 88.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) ZapB PF06005.12 EAY01852.1 - 0.057 13.9 0.2 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB PRE_C2HC PF07530.11 EAY01852.1 - 0.064 13.4 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Associated with zinc fingers DUF3839 PF12943.7 EAY01853.1 - 1.8e-84 283.0 4.4 2e-84 282.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY01853.1 - 0.045 13.6 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase KELK PF15796.5 EAY01853.1 - 0.078 13.4 0.1 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LRR_5 PF13306.6 EAY01854.1 - 5e-107 353.0 63.6 3.9e-35 120.6 9.8 3.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY01854.1 - 3.7e-09 36.2 7.9 0.12 12.1 0.2 6.5 4 2 2 6 6 6 5 Leucine rich repeat DUF3677 PF12432.8 EAY01855.1 - 0.26 11.6 2.3 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) CPSF_A PF03178.15 EAY01856.1 - 0.0017 17.7 1.1 0.0086 15.4 0.2 2.4 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EAY01856.1 - 0.052 13.8 0.0 16 5.8 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4939 PF16297.5 EAY01857.1 - 0.026 14.4 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) DUF488 PF04343.13 EAY01858.1 - 4.5e-29 101.5 0.7 5e-29 101.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 Mak10 PF04112.13 EAY01859.1 - 6.8e-05 22.4 0.2 0.00021 20.8 0.1 1.9 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase EMC3_TMCO1 PF01956.16 EAY01859.1 - 0.016 15.0 0.2 0.044 13.5 0.2 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TehB PF03848.14 EAY01860.1 - 0.0097 15.3 0.4 0.033 13.6 0.4 1.8 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF3839 PF12943.7 EAY01862.1 - 2.5e-117 390.6 6.6 2.8e-117 390.4 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Z1 PF10593.9 EAY01862.1 - 0.066 12.7 0.9 0.1 12.1 0.7 1.3 1 1 0 1 1 1 0 Z1 domain KELK PF15796.5 EAY01862.1 - 0.76 10.3 3.1 1.2 9.6 1.3 2.3 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase PF00069.25 EAY01863.1 - 6.4e-72 242.1 0.1 9.1e-72 241.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01863.1 - 1.5e-40 139.1 0.0 2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY01863.1 - 1.4e-08 34.1 0.4 4.5e-08 32.4 0.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAY01863.1 - 1.2e-05 25.0 0.6 9.6e-05 22.1 0.2 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EAY01863.1 - 4.1e-05 23.6 0.4 9.1e-05 22.5 0.3 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAY01863.1 - 0.00043 19.2 0.2 0.00066 18.6 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY01863.1 - 0.014 14.7 1.0 0.022 14.1 1.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAY01863.1 - 0.017 14.7 0.3 0.031 13.8 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 EAY01863.1 - 0.11 12.5 1.0 0.37 10.7 1.0 2.0 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins rve PF00665.26 EAY01864.1 - 5.6e-15 55.6 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EAY01864.1 - 3.7e-07 29.8 0.2 8.8e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain Hydrolase_6 PF13344.6 EAY01864.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EAY01865.1 - 1.5e-68 231.1 0.5 2.4e-68 230.4 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01865.1 - 7.2e-39 133.6 0.1 9.5e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY01865.1 - 2.1e-07 30.3 0.6 3.8e-07 29.4 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY01865.1 - 0.0009 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAY01865.1 - 0.0021 17.7 1.4 0.0027 17.3 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EAY01865.1 - 0.0024 17.5 0.7 0.0042 16.7 0.7 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EAY01865.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EAY01865.1 - 0.052 13.5 0.1 0.37 10.7 0.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PriA_CRR PF18319.1 EAY01866.1 - 0.0081 16.1 1.5 0.11 12.5 0.3 2.5 2 0 0 2 2 2 1 PriA DNA helicase Cys-rich region (CRR) domain Lactamase_B_2 PF12706.7 EAY01867.1 - 5.6e-31 107.6 0.0 6.9e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAY01867.1 - 1.3e-09 38.4 1.1 1e-08 35.4 0.6 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EAY01867.1 - 0.0018 17.7 0.3 0.0087 15.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAY01867.1 - 0.055 13.4 0.2 0.17 11.7 0.2 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.25 EAY01868.1 - 1.2e-65 221.5 0.9 1.5e-65 221.2 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01868.1 - 3e-31 108.7 0.3 9.3e-31 107.0 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01868.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAY01868.1 - 0.015 15.3 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAY01868.1 - 0.02 14.5 0.7 0.035 13.7 0.7 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAY01868.1 - 0.051 12.9 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EAY01869.1 - 1.1e-28 99.1 0.7 7.3e-16 58.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01869.1 - 2.1e-20 72.7 0.2 3.9e-12 46.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY01869.1 - 4.6e-06 26.6 0.1 0.0089 16.0 0.1 2.8 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 EAY01869.1 - 0.00019 21.4 0.0 0.19 11.8 0.0 2.4 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EAY01869.1 - 1 9.8 4.5 2.9 8.3 0.5 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain SieB PF14163.6 EAY01870.1 - 0.029 13.9 1.0 0.63 9.5 0.4 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF2533 PF10752.9 EAY01870.1 - 0.041 14.3 0.1 0.17 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) AI-2E_transport PF01594.16 EAY01870.1 - 0.046 12.9 2.8 0.076 12.2 2.8 1.4 1 0 0 1 1 1 0 AI-2E family transporter Ras PF00071.22 EAY01871.1 - 3.5e-46 156.8 0.0 4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY01871.1 - 1.1e-33 116.0 0.1 1.5e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY01871.1 - 6.2e-15 55.1 0.0 7.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAY01871.1 - 1.7e-08 34.3 0.1 5.2e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAY01871.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAY01871.1 - 0.00015 21.7 0.5 0.004 17.1 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EAY01871.1 - 0.0013 18.2 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EAY01871.1 - 0.0029 17.4 0.6 0.022 14.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EAY01871.1 - 0.0045 16.7 0.3 0.014 15.2 0.3 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EAY01871.1 - 0.0075 15.8 0.2 0.13 11.8 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 EAY01871.1 - 0.014 15.8 0.1 0.022 15.1 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EAY01871.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 EAY01871.1 - 0.049 13.6 0.1 0.07 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAY01871.1 - 0.075 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 EAY01871.1 - 0.14 11.8 0.6 23 4.5 0.2 2.9 1 1 2 3 3 3 0 SRP54-type protein, GTPase domain TniB PF05621.11 EAY01871.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein BTB PF00651.31 EAY01872.1 - 2.5e-17 63.1 0.0 4.7e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RhoGAP-FF1 PF16512.5 EAY01872.1 - 0.024 15.3 0.4 5.8 7.7 0.1 2.4 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain Peptidase_M20 PF01546.28 EAY01874.1 - 1.6e-13 50.9 0.3 2.4e-13 50.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAY01874.1 - 0.00028 20.8 0.1 0.00089 19.1 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EAY01874.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EAY01874.1 - 0.002 17.2 0.0 0.013 14.6 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_C1 PF00112.23 EAY01875.1 - 8.4e-73 245.1 6.7 1.3e-72 244.4 6.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAY01875.1 - 1.8e-08 34.7 0.4 3.4e-08 33.8 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAY01875.1 - 7.3e-06 25.0 0.7 0.00099 18.0 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family MatE PF01554.18 EAY01876.1 - 1.3e-30 106.2 24.7 1.1e-18 67.4 3.9 2.5 3 0 0 3 3 3 2 MatE TPR_17 PF13431.6 EAY01877.1 - 0.00048 20.3 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAY01877.1 - 0.0085 16.1 0.1 4.9 7.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 EAY01877.1 - 0.043 14.5 0.0 0.42 11.4 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat Rad10 PF03834.14 EAY01878.1 - 0.024 14.7 1.0 0.028 14.5 1.0 1.3 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Mito_carr PF00153.27 EAY01878.1 - 0.19 11.6 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein ubiquitin PF00240.23 EAY01881.1 - 9.2e-08 31.7 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAY01881.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAY01882.1 - 6.9e-14 51.4 0.1 1.6e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EAY01882.1 - 7.7e-06 25.7 0.6 1.8e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAY01882.1 - 0.0003 21.3 0.1 0.0022 18.5 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAY01882.1 - 0.0015 18.9 0.1 0.0028 18.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAY01882.1 - 0.023 14.8 0.1 0.052 13.7 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2313 PF10076.9 EAY01883.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF963 PF06131.11 EAY01884.1 - 1.4 8.4 6.3 2.3 7.7 3.1 2.6 2 1 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF4107 PF13389.6 EAY01885.1 - 1.6e-48 164.9 1.4 1.9e-48 164.7 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) VPS13 PF16908.5 EAY01888.1 - 3.3e-33 115.5 11.3 8.7e-33 114.1 3.5 4.4 4 1 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EAY01888.1 - 1.2e-21 76.9 7.3 1.5e-21 76.7 0.3 4.4 3 1 1 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EAY01888.1 - 0.00055 19.8 0.3 0.00055 19.8 0.3 3.4 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EAY01888.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Peptidase_S8 PF00082.22 EAY01889.1 - 5.2e-17 62.1 0.7 8.6e-17 61.3 0.7 1.3 1 1 0 1 1 1 1 Subtilase family Protocadherin PF08374.11 EAY01890.1 - 0.025 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Mid2 PF04478.12 EAY01890.1 - 0.057 13.3 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 EAY01890.1 - 0.059 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 EAY01890.1 - 0.12 13.3 0.0 0.25 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAY01890.1 - 0.13 12.2 2.8 0.2 11.6 2.3 1.7 1 1 0 1 1 1 0 TMEM154 protein family TALPID3 PF15324.6 EAY01890.1 - 2.9 5.4 15.1 4.2 4.9 15.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MULE PF10551.9 EAY01891.1 - 1.4e-10 41.4 0.2 4e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAY01891.1 - 0.025 13.4 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family DUF3781 PF12636.7 EAY01893.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAY01894.1 - 9.1e-34 117.0 3.3 1.1e-33 116.7 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Lipoxygenase PF00305.19 EAY01894.1 - 0.04 12.3 1.2 0.04 12.3 1.2 1.0 1 0 0 1 1 1 0 Lipoxygenase UL17 PF17640.2 EAY01895.1 - 0.089 12.8 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized UL17 FliJ PF02050.16 EAY01896.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4107 PF13389.6 EAY01897.1 - 3.9e-72 241.7 3.6 5.2e-72 241.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Amidase02_C PF12123.8 EAY01899.1 - 0.004 16.8 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAY01900.1 - 7.1e-132 438.2 11.3 7.9e-132 438.1 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF29 PF01724.16 EAY01900.1 - 0.027 14.7 0.1 0.093 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF5398 PF17376.2 EAY01900.1 - 0.23 12.1 2.2 0.55 10.9 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5398) KELK PF15796.5 EAY01900.1 - 0.5 10.8 2.6 0.96 10.0 0.7 2.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3839 PF12943.7 EAY01901.1 - 9.5e-08 31.8 1.6 1.7e-07 30.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DNA_pol_B_2 PF03175.13 EAY01902.1 - 9.7e-09 34.6 1.0 1.8e-08 33.7 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral gpUL132 PF11359.8 EAY01902.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Lac_bphage_repr PF06543.12 EAY01902.1 - 0.16 12.0 0.0 0.95 9.5 0.0 2.1 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor DUF1043 PF06295.12 EAY01903.1 - 0.054 13.5 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PadR PF03551.14 EAY01903.1 - 0.13 12.3 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF2939 PF11159.8 EAY01904.1 - 0.015 15.7 0.4 0.017 15.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAS_N PF17828.1 EAY01905.1 - 0.02 14.9 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAY01906.1 - 0.056 13.4 9.2 0.092 12.7 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.11 EAY01906.1 - 2.7 8.5 6.0 3.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPS2_interact PF15784.5 EAY01907.1 - 0.051 14.0 0.5 0.062 13.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY01907.1 - 0.12 11.3 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliJ PF02050.16 EAY01908.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Ank_2 PF12796.7 EAY01909.1 - 3.6e-59 197.3 1.5 5.3e-16 59.0 0.0 5.0 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAY01909.1 - 4.9e-36 121.6 1.0 3.1e-05 24.2 0.0 8.3 6 1 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAY01909.1 - 2.9e-34 116.7 0.9 2.8e-08 33.9 0.0 6.7 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY01909.1 - 1.7e-32 111.4 0.1 1.9e-07 31.5 0.0 5.6 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01909.1 - 4e-32 106.7 0.2 0.0014 19.0 0.0 8.2 6 1 1 7 7 7 7 Ankyrin repeat BACK PF07707.15 EAY01909.1 - 0.014 15.5 2.2 0.028 14.5 2.2 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch AF0941-like PF14591.6 EAY01909.1 - 0.2 12.2 4.7 0.15 12.6 1.5 2.6 1 1 1 2 2 2 0 AF0941-like DUF563 PF04577.14 EAY01910.1 - 1.8e-11 44.6 0.0 3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Beta_helix PF13229.6 EAY01911.1 - 7.5e-05 22.6 6.2 0.012 15.5 4.7 2.7 1 1 1 2 2 2 2 Right handed beta helix region Ribosomal_L31e PF01198.19 EAY01912.1 - 3.1e-19 69.0 2.2 4.4e-19 68.5 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e V_cholerae_RfbT PF05575.11 EAY01914.1 - 0.04 13.2 0.2 0.11 11.8 0.2 1.7 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein SNARE PF05739.19 EAY01915.1 - 4.8e-05 23.3 2.5 4.8e-05 23.3 2.5 2.1 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 EAY01915.1 - 0.0057 14.7 1.3 0.0062 14.6 1.3 1.1 1 0 0 1 1 1 1 Prominin DUF3671 PF12420.8 EAY01915.1 - 0.0093 16.0 1.6 0.013 15.6 1.4 1.3 1 1 0 1 1 1 1 Protein of unknown function DUF3584 PF12128.8 EAY01915.1 - 0.011 13.3 1.9 0.012 13.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EAY01915.1 - 0.014 15.4 6.5 0.021 14.8 6.5 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 EAY01915.1 - 0.017 14.5 1.8 0.02 14.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 EAY01915.1 - 0.019 15.3 0.2 0.025 14.9 0.2 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SOAR PF16533.5 EAY01915.1 - 0.021 14.8 1.9 0.038 14.0 0.2 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region V-SNARE_C PF12352.8 EAY01915.1 - 0.025 14.9 6.0 0.14 12.4 6.1 2.0 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF5305 PF17231.2 EAY01915.1 - 0.026 13.9 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ribosomal_S6e PF01092.19 EAY01915.1 - 0.031 14.3 0.7 0.036 14.0 0.7 1.0 1 0 0 1 1 1 0 Ribosomal protein S6e BSMAP PF12280.8 EAY01915.1 - 0.034 14.3 0.2 0.041 14.1 0.2 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein YojJ PF10372.9 EAY01915.1 - 0.049 13.7 3.6 0.063 13.4 1.1 1.9 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Use1 PF09753.9 EAY01915.1 - 0.079 12.7 5.0 0.083 12.6 5.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 HIP1_clath_bdg PF16515.5 EAY01915.1 - 0.08 13.6 5.4 0.095 13.3 5.4 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 EAY01915.1 - 0.086 11.5 4.4 0.098 11.3 4.4 1.0 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EAY01915.1 - 0.13 12.3 4.4 0.19 11.8 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FliJ PF02050.16 EAY01915.1 - 0.21 11.8 7.7 0.25 11.6 7.7 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein LXG PF04740.12 EAY01915.1 - 0.25 11.0 8.9 0.33 10.7 8.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily She9_MDM33 PF05546.11 EAY01915.1 - 0.42 10.4 5.3 0.54 10.0 5.3 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family DUF745 PF05335.13 EAY01915.1 - 0.44 10.2 8.1 0.48 10.1 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TBCA PF02970.16 EAY01915.1 - 0.45 10.9 5.4 0.78 10.1 5.4 1.4 1 1 0 1 1 1 0 Tubulin binding cofactor A XhlA PF10779.9 EAY01915.1 - 0.48 10.7 11.4 1.8 8.8 7.7 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Sec20 PF03908.13 EAY01915.1 - 1.4 8.9 7.1 10 6.1 7.1 2.0 1 1 0 1 1 1 0 Sec20 DUF3361 PF11841.8 EAY01916.1 - 1.4e-05 25.1 4.8 0.0055 16.7 0.9 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3361) HSCB_C PF07743.13 EAY01916.1 - 0.0036 17.8 4.6 0.31 11.6 0.1 2.6 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain Vitellogenin_N PF01347.22 EAY01916.1 - 0.0068 14.9 2.2 0.2 10.0 0.4 2.1 1 1 0 2 2 2 2 Lipoprotein amino terminal region Apolipoprotein PF01442.18 EAY01916.1 - 0.13 12.2 0.4 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GreA_GreB_N PF03449.15 EAY01917.1 - 0.035 14.3 3.7 0.035 14.3 3.7 2.3 2 2 0 2 2 2 0 Transcription elongation factor, N-terminal RRM_1 PF00076.22 EAY01918.1 - 5.2e-15 55.0 0.0 7.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAY01918.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAY01918.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PI3_PI4_kinase PF00454.27 EAY01919.1 - 1.7e-49 168.9 0.0 3.7e-49 167.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EAY01919.1 - 1.9e-09 37.8 4.9 8.4e-09 35.7 0.4 3.7 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 EAY01919.1 - 3e-08 33.8 0.9 1.9e-05 24.7 0.0 5.2 3 2 1 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 EAY01919.1 - 1.8e-06 27.6 0.1 4.6e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EAY01919.1 - 2.9e-06 27.6 0.2 0.75 10.2 0.0 6.7 6 1 1 7 7 7 1 HEAT repeats HEAT PF02985.22 EAY01919.1 - 0.0015 18.6 7.1 5.4 7.6 0.1 5.8 5 0 0 5 5 5 2 HEAT repeat RIX1 PF08167.12 EAY01919.1 - 0.063 13.0 5.5 1.3 8.7 0.0 4.7 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis TPR_7 PF13176.6 EAY01919.1 - 0.087 12.9 0.0 0.76 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cnd1 PF12717.7 EAY01919.1 - 0.97 9.5 14.1 18 5.4 0.1 6.6 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EAY01919.1 - 6.8 6.9 6.5 32 4.7 0.0 5.3 7 1 1 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 ASH PF15780.5 EAY01921.1 - 6.9e-27 93.5 10.1 1.6e-05 25.0 0.0 8.9 8 2 0 8 8 8 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EAY01921.1 - 7.7e-13 48.3 1.9 0.064 13.3 0.0 8.2 7 1 0 7 7 7 3 Protein of unknown function (DUF1573) PapD-like PF14874.6 EAY01921.1 - 3.5e-10 39.9 0.3 0.23 11.6 0.1 5.9 5 1 0 5 5 5 3 Flagellar-associated PapD-like MYCBPAP PF14646.6 EAY01921.1 - 3.2e-08 33.0 4.6 0.51 9.2 0.0 5.9 4 2 2 6 6 6 3 MYCBP-associated protein family TMEM131_like PF12371.8 EAY01921.1 - 7.4e-06 26.1 2.7 0.37 11.1 0.0 5.8 5 1 0 5 5 5 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 EAY01921.1 - 1.5e-05 24.8 1.2 0.67 9.8 0.1 5.0 5 0 0 5 5 5 2 MSP (Major sperm protein) domain fn3_5 PF06280.12 EAY01921.1 - 0.032 14.9 5.9 10 6.8 0.1 5.2 5 1 0 5 5 5 0 Fn3-like domain H_lectin PF09458.10 EAY01921.1 - 0.045 13.9 1.5 7.9 6.7 0.1 4.4 4 0 0 4 4 4 0 H-type lectin domain DUF5001 PF16392.5 EAY01921.1 - 0.24 11.3 1.9 24 4.9 0.0 3.7 3 0 0 3 3 3 0 Ig-like domain Ank_4 PF13637.6 EAY01922.1 - 6.5e-42 141.4 9.5 1.3e-12 47.9 0.1 4.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01922.1 - 4.4e-33 112.3 6.8 1.6e-07 31.5 0.1 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 EAY01922.1 - 1.2e-30 106.0 11.6 5.9e-18 65.2 4.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01922.1 - 6.1e-28 96.5 8.2 7.5e-12 45.3 0.5 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01922.1 - 1.3e-24 83.6 5.1 1.7e-06 27.9 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat CbiK PF06180.11 EAY01922.1 - 0.02 14.2 0.4 0.14 11.4 0.1 2.0 1 1 1 2 2 2 0 Cobalt chelatase (CbiK) RNase_PH_C PF03725.15 EAY01922.1 - 0.11 12.5 0.1 2.5 8.2 0.1 2.6 1 1 2 3 3 3 0 3' exoribonuclease family, domain 2 PrmC_N PF17827.1 EAY01922.1 - 0.15 12.7 0.3 27 5.4 0.1 3.2 2 1 1 3 3 3 0 PrmC N-terminal domain DUF348 PF03990.14 EAY01922.1 - 0.16 11.8 1.2 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain DUF3447 PF11929.8 EAY01923.1 - 7.6e-35 118.7 3.3 1.1e-34 118.2 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY01923.1 - 0.0019 18.8 0.0 0.0032 18.0 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01923.1 - 0.022 15.3 0.1 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF1512 PF07431.12 EAY01924.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Raptor_N PF14538.6 EAY01925.1 - 1.5e-23 83.4 0.1 3.9e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain PQQ_3 PF13570.6 EAY01925.1 - 0.18 12.4 0.2 75 4.0 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain DUF3447 PF11929.8 EAY01926.1 - 7.9e-37 125.1 8.8 7.9e-37 125.1 8.8 4.3 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY01926.1 - 2.6e-36 123.5 2.6 3.5e-11 43.4 0.1 6.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EAY01926.1 - 8.8e-36 120.8 3.2 2.1e-08 34.3 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 EAY01926.1 - 2.7e-35 120.8 12.5 3.7e-18 65.9 1.8 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY01926.1 - 7.4e-34 112.0 4.7 4.9e-07 29.6 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAY01926.1 - 1.7e-25 88.7 4.9 1.5e-10 41.1 0.4 4.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Porin_O_P PF07396.11 EAY01926.1 - 0.046 12.9 0.2 0.071 12.3 0.2 1.4 1 0 0 1 1 1 0 Phosphate-selective porin O and P FAT PF02259.23 EAY01926.1 - 0.052 12.8 0.2 0.13 11.4 0.1 1.7 1 1 1 2 2 2 0 FAT domain Thioredoxin PF00085.20 EAY01928.1 - 1.1e-10 41.4 0.0 3.9e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EAY01928.1 - 0.0033 17.7 0.2 0.085 13.2 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAY01928.1 - 0.017 15.3 0.1 0.046 13.9 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EAY01928.1 - 0.035 14.6 0.9 1.2 9.6 0.5 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain DUF3674 PF12426.8 EAY01928.1 - 0.06 13.4 0.4 0.18 11.9 0.4 1.8 1 0 0 1 1 1 0 RNA dependent RNA polymerase Thioredoxin_9 PF14595.6 EAY01928.1 - 0.12 12.1 0.3 0.3 10.9 0.3 1.7 1 0 0 1 1 1 0 Thioredoxin UCH PF00443.29 EAY01929.1 - 2.3e-30 105.9 0.0 2.3e-30 105.9 0.0 4.0 3 2 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DUF3824 PF12868.7 EAY01929.1 - 0.43 11.2 8.6 0.8 10.4 8.6 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TraI_2_C PF07515.11 EAY01929.1 - 1.7 8.6 11.7 1.4 8.9 6.6 3.0 3 0 0 3 3 3 0 Putative conjugal transfer nickase/helicase TraI C-term TFIIA PF03153.13 EAY01929.1 - 2.3 8.1 30.4 4 7.3 30.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 EAY01930.1 - 9.6e-28 97.3 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01930.1 - 1.3e-10 41.0 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAY01930.1 - 3.5e-09 36.0 0.0 5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY01930.1 - 0.00051 19.5 0.1 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY01930.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAY01930.1 - 0.014 15.0 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MULE PF10551.9 EAY01931.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain HTH_Tnp_1_2 PF13022.6 EAY01931.1 - 0.012 15.7 2.5 0.015 15.5 0.3 2.1 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase Z1 PF10593.9 EAY01931.1 - 2.6 7.5 9.9 12 5.3 0.1 2.2 2 0 0 2 2 2 0 Z1 domain zf-CCCH_7 PF18586.1 EAY01931.1 - 2.7 8.4 5.3 4.2 7.8 0.2 2.8 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PqiA PF04403.13 EAY01932.1 - 3.9e-06 26.8 2.2 3.9e-06 26.8 2.2 3.8 4 0 0 4 4 4 2 Paraquat-inducible protein A CDC45 PF02724.14 EAY01932.1 - 0.0031 15.9 0.4 0.0037 15.6 0.4 1.1 1 0 0 1 1 1 1 CDC45-like protein LYRIC PF15686.5 EAY01932.1 - 0.012 15.2 11.1 0.016 14.8 11.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Connexin PF00029.19 EAY01932.1 - 0.039 13.7 5.4 0.19 11.4 5.4 2.2 1 1 0 1 1 1 0 Connexin DUF4604 PF15377.6 EAY01932.1 - 0.7 10.3 18.9 1.1 9.6 18.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF5365 PF17326.2 EAY01933.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5365) PWI PF01480.17 EAY01933.1 - 0.033 14.5 0.5 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 PWI domain Pkinase PF00069.25 EAY01934.1 - 2.4e-57 194.3 0.0 3.8e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01934.1 - 3.2e-33 115.1 0.0 5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAY01934.1 - 1.1e-07 32.1 0.0 7.3e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAY01934.1 - 7.1e-06 25.5 0.0 2.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAY01934.1 - 9.8e-06 24.6 0.1 1.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EAY01934.1 - 0.00027 20.0 0.0 0.00076 18.5 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY01934.1 - 0.00037 19.9 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAY01934.1 - 0.00046 19.8 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EAY01934.1 - 0.00089 18.9 2.8 0.76 9.4 0.0 2.8 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EAY01934.1 - 0.011 14.8 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EAY01934.1 - 0.024 14.2 0.3 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ligase_CoA PF00549.19 EAY01935.1 - 2.7e-27 95.5 0.7 4.4e-27 94.8 0.7 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EAY01935.1 - 1.7e-26 92.7 0.6 1.7e-26 92.7 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EAY01935.1 - 1.1e-08 35.0 0.1 1.9e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 EAY01935.1 - 0.0009 20.1 1.8 0.0016 19.3 0.3 2.1 2 1 1 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 EAY01935.1 - 0.00094 18.8 0.3 0.0019 17.8 0.3 1.6 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 EAY01935.1 - 0.0019 18.7 0.1 0.0038 17.7 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain ELFV_dehydrog PF00208.21 EAY01935.1 - 0.0023 17.7 0.1 0.0052 16.5 0.1 1.5 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HSP70 PF00012.20 EAY01936.1 - 9.9e-18 63.6 12.5 5.8e-17 61.1 3.0 3.0 1 1 1 2 2 2 1 Hsp70 protein Laminin_II PF06009.12 EAY01936.1 - 0.019 15.0 3.7 0.019 15.0 3.7 2.1 2 0 0 2 2 2 0 Laminin Domain II PriC PF07445.12 EAY01936.1 - 0.035 14.0 2.7 0.065 13.2 2.7 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC GvpL_GvpF PF06386.11 EAY01936.1 - 0.12 12.3 1.0 0.27 11.1 1.0 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Phage_terminase PF10668.9 EAY01936.1 - 0.17 11.9 0.6 0.55 10.3 0.3 2.0 2 0 0 2 2 2 0 Phage terminase small subunit EF-hand_7 PF13499.6 EAY01936.1 - 0.25 11.8 3.6 4.5 7.8 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain pair GramPos_pilinBB PF16569.5 EAY01938.1 - 0.38 11.6 3.3 0.97 10.3 0.2 2.4 2 1 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain DUF3473 PF11959.8 EAY01938.1 - 0.57 10.2 3.0 0.5 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) ARL2_Bind_BART PF11527.8 EAY01939.1 - 6.8e-23 81.0 4.1 1.2e-22 80.2 4.1 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Alba PF01918.21 EAY01939.1 - 0.033 14.0 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Alba DUF3895 PF13034.6 EAY01939.1 - 0.037 14.0 1.4 0.079 13.0 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3895) MSG PF02349.15 EAY01939.1 - 0.046 13.9 0.7 0.1 12.8 0.7 1.6 1 1 0 1 1 1 0 Major surface glycoprotein CSN7a_helixI PF18392.1 EAY01939.1 - 0.31 11.0 3.1 10 6.1 0.2 2.5 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Myb_DNA-binding PF00249.31 EAY01940.1 - 9.1e-29 99.4 0.2 8.3e-14 51.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY01940.1 - 2e-23 82.4 1.4 9.3e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EAY01940.1 - 0.0023 18.2 4.3 1.5 9.2 0.7 3.0 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY01940.1 - 0.0024 17.7 0.1 0.016 15.1 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EAY01940.1 - 0.0053 16.9 0.1 0.49 10.6 0.1 2.8 2 1 0 2 2 2 1 Rap1 Myb domain DUF4167 PF13763.6 EAY01940.1 - 0.0084 16.2 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4167) SLIDE PF09111.10 EAY01940.1 - 0.009 16.0 0.1 0.82 9.7 0.0 2.4 1 1 1 2 2 2 1 SLIDE DUF722 PF05263.11 EAY01940.1 - 0.03 14.5 0.1 3.3 7.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF722) Poxvirus_B22R_N PF13169.6 EAY01940.1 - 0.078 13.5 0.2 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal Myb_DNA-bind_5 PF13873.6 EAY01940.1 - 0.19 11.8 2.2 5.2 7.2 0.1 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EAY01941.1 - 4.7e-54 183.5 0.0 5.8e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01941.1 - 3.7e-34 118.2 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01941.1 - 9.7e-07 28.4 0.0 2.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAY01941.1 - 0.019 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C1 PF00112.23 EAY01942.1 - 9.4e-72 241.6 11.2 1.2e-71 241.3 11.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAY01942.1 - 5.9e-11 42.6 0.1 1e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAY01942.1 - 2.4e-05 23.3 2.7 0.0063 15.3 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family rve_2 PF13333.6 EAY01942.1 - 0.092 12.9 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Integrase core domain DUF4149 PF13664.6 EAY01943.1 - 0.076 13.3 6.6 1.6 9.1 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3021 PF11457.8 EAY01943.1 - 0.93 9.8 11.0 2.6 8.4 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) DUF2070 PF09843.9 EAY01943.1 - 1 7.6 10.3 1.2 7.3 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATP_synt_H PF05493.13 EAY01943.1 - 1.3 9.5 6.9 3 8.4 3.5 2.8 2 1 0 2 2 2 0 ATP synthase subunit H Pox_A14 PF05767.12 EAY01943.1 - 1.4 9.1 14.7 0.037 14.2 4.9 2.7 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 DUF4181 PF13789.6 EAY01943.1 - 1.8 8.9 10.0 0.057 13.7 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) DUF4418 PF14387.6 EAY01943.1 - 2.8 8.2 11.4 0.11 12.7 5.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) DUF2568 PF10823.8 EAY01943.1 - 4.8 7.5 13.4 0.19 12.0 1.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2568) DUF4131 PF13567.6 EAY01943.1 - 5.6 6.6 11.7 8.5 6.0 4.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) TauE PF01925.19 EAY01943.1 - 9.9 5.7 18.0 6 6.4 13.9 2.3 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE tRNA-synt_1c PF00749.21 EAY01944.1 - 2.8e-85 286.0 0.0 3.9e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAY01944.1 - 6.4e-21 75.0 0.1 1.5e-20 73.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EAY01944.1 - 3.7e-05 23.8 0.0 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAY01944.1 - 0.0031 17.5 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAY01944.1 - 0.012 15.9 0.1 0.034 14.4 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EAY01944.1 - 0.022 14.1 0.4 0.1 11.9 0.1 2.1 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 EAY01946.1 - 4.4e-57 193.4 0.0 5.8e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01946.1 - 1.2e-42 146.0 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY01946.1 - 9.5e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAY01946.1 - 0.038 13.4 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY01946.1 - 0.095 12.6 0.0 5.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Beach PF02138.18 EAY01947.1 - 1.6e-74 250.8 0.0 2.9e-74 249.9 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EAY01947.1 - 0.0003 20.9 0.1 0.0009 19.4 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EAY01947.1 - 0.18 12.7 2.4 15 6.6 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-B_box PF00643.24 EAY01947.1 - 5.2 7.3 13.7 26 5.1 13.7 2.1 1 1 0 1 1 1 0 B-box zinc finger DUF3149 PF11346.8 EAY01949.1 - 0.033 13.8 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF3781 PF12636.7 EAY01953.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) UCH PF00443.29 EAY01954.1 - 1.3e-37 129.7 3.2 1.7e-37 129.3 3.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAY01954.1 - 5.6e-11 42.9 0.2 5.6e-11 42.9 0.2 3.1 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 EAY01954.1 - 4.1e-07 29.9 8.2 8.4e-05 22.3 0.2 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3725 PF12523.8 EAY01954.1 - 0.096 13.0 0.3 0.24 11.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) RRM_1 PF00076.22 EAY01957.1 - 2.2e-24 85.0 0.4 3.3e-24 84.5 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAY01957.1 - 0.003 17.6 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EAY01957.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 EAY01957.1 - 0.069 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_occluded PF16842.5 EAY01957.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4407 PF14362.6 EAY01957.1 - 5.5 6.3 5.8 6.7 6.0 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPTA PF01239.22 EAY01958.1 - 3.6e-32 109.2 24.0 7.5e-09 35.0 1.5 4.8 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Sec10 PF07393.11 EAY01959.1 - 2.5e-142 475.8 16.3 5.3e-81 273.1 4.1 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 DUF948 PF06103.11 EAY01959.1 - 0.017 15.4 2.4 1.1 9.6 0.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Metallophos PF00149.28 EAY01960.1 - 1.6e-18 68.0 0.0 2.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF682 PF05081.12 EAY01961.1 - 0.01 15.6 0.4 0.011 15.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF682) TENA_THI-4 PF03070.16 EAY01961.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Pkinase PF00069.25 EAY01962.1 - 7.6e-22 77.9 1.0 8.7e-22 77.7 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01962.1 - 1.2e-13 51.0 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAY01962.1 - 0.0011 17.9 0.2 0.0014 17.5 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY01962.1 - 0.023 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY01962.1 - 0.031 14.2 0.1 0.071 13.0 0.1 1.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Strumpellin PF10266.9 EAY01964.1 - 0 1226.5 20.0 0 1226.3 20.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF3447 PF11929.8 EAY01965.1 - 7.7e-07 29.0 1.8 7.7e-07 29.0 1.8 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) PA14 PF07691.12 EAY01966.1 - 0.1 12.4 0.4 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 PA14 domain KASH_CCD PF14662.6 EAY01967.1 - 2.2e-05 24.4 17.5 2.2e-05 24.4 17.5 19.7 2 2 18 21 21 21 5 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 EAY01967.1 - 0.00017 21.3 34.7 0.00017 21.3 34.7 17.9 3 2 15 20 20 20 3 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EAY01967.1 - 0.00017 20.6 15.2 0.00017 20.6 15.2 20.4 2 2 18 21 21 21 11 Spc7 kinetochore protein CALCOCO1 PF07888.11 EAY01967.1 - 0.0011 17.9 40.3 0.0011 17.9 40.3 13.4 1 1 13 14 14 14 3 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 EAY01967.1 - 0.0011 18.3 25.6 0.0011 18.3 25.6 20.3 2 2 15 19 19 19 11 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EAY01967.1 - 0.0019 18.5 43.9 0.0019 18.5 43.9 20.8 1 1 18 19 19 19 5 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 EAY01967.1 - 0.0021 18.1 31.9 0.0021 18.1 31.9 23.7 4 4 19 25 25 25 5 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 EAY01967.1 - 0.0089 16.9 6.8 0.0089 16.9 6.8 25.0 3 3 20 24 24 24 3 cGMP-dependent protein kinase interacting domain DUF3470 PF11953.8 EAY01969.1 - 0.14 12.1 3.0 1.2 9.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) DUF2935 PF11155.8 EAY01969.1 - 1.4 9.3 24.5 7.9e+02 0.4 12.0 6.3 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) Kinesin PF00225.23 EAY01970.1 - 2.1e-77 260.3 9.6 2.1e-77 260.3 9.6 2.9 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EAY01970.1 - 6.5e-25 87.8 0.3 6.5e-25 87.8 0.3 2.3 2 0 0 2 2 2 1 Microtubule binding DivIC PF04977.15 EAY01970.1 - 0.0074 16.0 32.9 0.077 12.8 7.1 5.2 3 2 2 5 5 5 2 Septum formation initiator Pox_A_type_inc PF04508.12 EAY01970.1 - 0.012 15.4 3.2 0.012 15.4 3.2 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.7 EAY01970.1 - 0.017 15.3 5.2 0.017 15.3 5.2 4.2 2 1 2 4 4 4 0 Tropomyosin like SlyX PF04102.12 EAY01970.1 - 0.02 15.5 26.1 0.51 11.0 2.4 5.0 2 1 2 4 4 4 0 SlyX TolA_bind_tri PF16331.5 EAY01970.1 - 0.023 14.8 1.3 0.023 14.8 1.3 4.1 3 1 0 3 3 3 0 TolA binding protein trimerisation DUF4140 PF13600.6 EAY01970.1 - 0.35 11.3 22.4 0.53 10.7 0.4 4.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EAY01970.1 - 0.43 9.4 40.7 0.23 10.3 17.5 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 EAY01970.1 - 0.87 9.7 18.0 0.18 11.9 0.5 4.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 EAY01970.1 - 1.3 8.8 46.8 0.25 11.2 19.9 4.4 3 2 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 EAY01970.1 - 2.9 7.9 39.7 0.13 12.2 1.3 5.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EAY01970.1 - 3.1 8.3 34.7 0.16 12.5 8.1 4.2 4 0 0 4 4 4 0 Cell division protein ZapB TSC22 PF01166.18 EAY01970.1 - 3.9 7.8 18.3 0.87 9.9 0.3 4.8 3 1 1 4 4 4 0 TSC-22/dip/bun family YabA PF06156.13 EAY01970.1 - 6.4 7.5 34.9 0.36 11.5 4.2 4.2 3 1 2 5 5 4 0 Initiation control protein YabA DUF484 PF04340.12 EAY01970.1 - 7.5 6.2 10.3 0.57 9.8 1.0 3.3 3 1 0 4 4 4 0 Protein of unknown function, DUF484 Syntaxin-6_N PF09177.11 EAY01970.1 - 8 7.1 30.2 0.6 10.7 3.3 4.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal RNA_pol_Rpb4 PF03874.16 EAY01972.1 - 0.0077 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2427 PF10348.9 EAY01973.1 - 0.17 11.7 1.0 0.35 10.7 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) WD40 PF00400.32 EAY01974.1 - 5.9e-08 33.2 4.6 0.34 11.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY01974.1 - 0.00052 20.3 0.0 0.62 10.4 0.0 4.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EAY01976.1 - 3.8e-08 33.0 0.0 4.6e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY01976.1 - 0.0039 16.5 0.0 0.0039 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CDO_I PF05995.12 EAY01976.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Cysteine dioxygenase type I DUF682 PF05081.12 EAY01977.1 - 0.016 15.0 0.2 0.017 14.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF682) TENA_THI-4 PF03070.16 EAY01977.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family C2 PF00168.30 EAY01979.1 - 3e-14 53.2 0.3 5.1e-13 49.2 0.0 2.5 2 1 0 2 2 2 1 C2 domain ERM PF00769.19 EAY01979.1 - 0.0092 15.8 8.1 0.013 15.3 8.1 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family RasGAP_C PF03836.15 EAY01979.1 - 0.014 15.5 10.0 0.035 14.2 10.0 1.7 1 0 0 1 1 1 0 RasGAP C-terminus YabA PF06156.13 EAY01979.1 - 0.048 14.3 11.9 0.15 12.7 11.8 2.0 1 1 0 1 1 1 0 Initiation control protein YabA NtCtMGAM_N PF16863.5 EAY01979.1 - 0.14 12.3 8.7 0.19 11.9 7.1 2.1 1 1 1 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase LMBR1 PF04791.16 EAY01979.1 - 0.15 10.9 5.8 0.19 10.6 5.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 EAY01979.1 - 0.17 11.0 12.1 0.25 10.4 12.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Takusan PF04822.13 EAY01979.1 - 0.51 10.2 14.2 2.7 7.9 1.3 2.9 2 1 0 2 2 2 0 Takusan Peptidase_M41 PF01434.18 EAY01979.1 - 0.71 9.7 3.9 0.48 10.2 1.8 1.7 2 0 0 2 2 2 0 Peptidase family M41 APG6_N PF17675.1 EAY01979.1 - 0.76 10.3 12.6 0.28 11.7 9.5 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region YlqD PF11068.8 EAY01979.1 - 2.6 8.4 13.6 9.3 6.6 13.6 2.0 1 1 0 1 1 1 0 YlqD protein HIP1_clath_bdg PF16515.5 EAY01979.1 - 3.8 8.2 12.9 2.8 8.6 10.3 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DNA_pol_B_2 PF03175.13 EAY01980.1 - 2e-17 63.2 4.6 3.4e-17 62.5 4.6 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PyrI PF01948.18 EAY01980.1 - 0.069 13.4 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain PSP PF04046.16 EAY01981.1 - 0.071 13.0 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY01982.1 - 0.036 14.6 4.0 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY01983.1 - 0.032 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4116 PF13475.6 EAY01984.1 - 0.013 15.2 0.8 0.031 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Mito_fiss_reg PF05308.11 EAY01986.1 - 0.11 12.6 0.5 0.12 12.5 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAY01986.1 - 0.77 9.2 2.6 0.77 9.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal I_LWEQ PF01608.17 EAY01987.1 - 0.02 15.1 2.1 0.042 14.1 2.1 1.5 1 0 0 1 1 1 0 I/LWEQ domain Alpha_Helical PF18489.1 EAY01987.1 - 0.2 11.9 3.5 0.45 10.7 0.9 2.2 2 0 0 2 2 2 0 Alpha helical domain DUF3918 PF13056.6 EAY01987.1 - 0.21 11.2 0.5 0.41 10.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Goodbye PF17109.5 EAY01988.1 - 0.02 15.4 1.3 0.024 15.1 1.3 1.3 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain DUF2570 PF10828.8 EAY01988.1 - 0.034 13.9 1.7 0.036 13.9 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CDI PF02234.19 EAY01988.1 - 5.3 7.3 7.8 10 6.4 4.5 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor Ank_2 PF12796.7 EAY01989.1 - 5.1e-21 75.1 0.8 6.8e-18 65.0 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY01989.1 - 1.3e-15 57.2 0.3 1.4e-09 38.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01989.1 - 1.2e-14 52.9 0.1 7.5e-05 22.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAY01989.1 - 9.6e-14 51.6 0.2 4.3e-07 30.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAY01989.1 - 2.4e-07 30.9 0.1 0.00023 21.5 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat ATG16 PF08614.11 EAY01990.1 - 0.00089 19.5 11.2 0.0023 18.2 2.2 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 EAY01990.1 - 0.0058 17.0 1.1 0.0058 17.0 1.1 3.0 2 1 1 3 3 3 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator OmpH PF03938.14 EAY01990.1 - 0.0072 16.7 16.6 0.073 13.4 3.6 3.0 2 1 1 3 3 3 3 Outer membrane protein (OmpH-like) Phage_RpbA PF10789.9 EAY01990.1 - 0.027 14.5 3.1 0.06 13.4 0.3 2.7 1 1 2 3 3 3 0 Phage RNA polymerase binding, RpbA Peptidase_C10 PF01640.17 EAY01990.1 - 0.047 14.0 0.3 0.22 11.8 0.0 2.1 1 1 1 2 2 2 0 Peptidase C10 family DUF4407 PF14362.6 EAY01990.1 - 0.058 12.7 8.8 0.11 11.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EAY01990.1 - 0.11 12.6 16.6 0.12 12.4 6.5 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 EAY01990.1 - 0.5 10.6 9.5 3.8 7.8 0.8 2.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 MatP_C PF17414.2 EAY01990.1 - 0.51 10.6 5.8 7.5 6.8 0.3 3.3 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Swi5 PF07061.11 EAY01990.1 - 0.59 10.3 10.6 1 9.5 2.7 2.9 3 0 0 3 3 2 0 Swi5 Med21 PF11221.8 EAY01990.1 - 1.3 9.3 10.2 2.6 8.3 2.9 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex COG2 PF06148.11 EAY01990.1 - 1.3 9.1 8.9 3.8 7.6 1.7 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.19 EAY01990.1 - 1.4 8.6 12.0 0.51 10.0 3.4 2.3 2 0 0 2 2 2 0 GrpE CRR7 PF12095.8 EAY01990.1 - 1.5 9.3 6.2 3.2 8.3 0.1 3.2 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Cep57_MT_bd PF06657.13 EAY01990.1 - 1.7 9.2 10.0 3.3 8.2 0.3 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Holin_BhlA PF10960.8 EAY01990.1 - 2.3 8.3 7.0 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 BhlA holin family TPD52 PF04201.15 EAY01990.1 - 2.7 7.6 10.7 0.12 12.0 3.8 2.1 2 1 0 2 2 2 0 Tumour protein D52 family DUF3450 PF11932.8 EAY01990.1 - 3.6 6.8 17.7 0.4 10.0 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) LOH1CR12 PF10158.9 EAY01990.1 - 5 7.2 8.7 1.3 9.1 3.4 2.1 2 0 0 2 2 2 0 Tumour suppressor protein MRPL52 PF18699.1 EAY01990.1 - 6.4 7.0 13.5 4.4 7.6 0.6 2.7 2 1 0 2 2 2 0 Mitoribosomal protein mL52 Metallophos PF00149.28 EAY01992.1 - 3.9e-32 112.4 0.0 4.8e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAY01992.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 EAY01993.1 - 6.8e-20 71.4 1.3 3.5e-06 27.5 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY01993.1 - 1.5e-11 44.5 1.1 0.0071 16.9 0.1 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY01993.1 - 4.8e-11 42.7 0.0 0.002 18.4 0.0 5.8 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY01993.1 - 1.2e-09 37.6 5.1 0.068 13.8 0.0 7.7 8 1 1 9 9 9 2 Ankyrin repeat DUF3447 PF11929.8 EAY01993.1 - 1.4e-07 31.4 28.4 2.4e-07 30.6 1.0 5.8 3 2 2 6 6 6 3 Domain of unknown function (DUF3447) Ank PF00023.30 EAY01993.1 - 2.6e-06 27.6 0.8 0.95 10.0 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat DUF563 PF04577.14 EAY01994.1 - 4.2e-33 115.3 0.5 8.7e-33 114.2 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TRIC PF05197.13 EAY01994.1 - 0.047 13.3 0.3 0.087 12.4 0.3 1.3 1 0 0 1 1 1 0 TRIC channel DUF957 PF06117.11 EAY01995.1 - 0.12 12.0 0.6 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) HD_3 PF13023.6 EAY01996.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.7 3 0 0 3 3 3 0 HD domain Zw10 PF06248.13 EAY01997.1 - 0.16 10.5 0.2 0.21 10.1 0.2 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Arteri_Gl PF00951.18 EAY01997.1 - 1.1 9.0 8.1 1.9 8.3 5.9 2.2 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Glyco_trans_1_3 PF13528.6 EAY01998.1 - 0.22 10.7 0.0 1 8.5 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 1 zf-RING_2 PF13639.6 EAY02000.1 - 2.5e-12 46.9 10.8 5.3e-12 45.9 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAY02000.1 - 1.8e-08 34.5 7.0 4.4e-08 33.3 7.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAY02000.1 - 1.3e-07 31.4 10.6 2.2e-07 30.6 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAY02000.1 - 2.7e-07 30.4 6.3 4.7e-07 29.7 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EAY02000.1 - 1.7e-06 27.7 7.1 1.7e-06 27.7 7.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EAY02000.1 - 5.1e-05 23.0 6.4 0.0001 22.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAY02000.1 - 8.3e-05 22.4 10.1 0.00015 21.5 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAY02000.1 - 0.00015 21.7 4.2 0.00037 20.5 4.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAY02000.1 - 0.00082 19.3 5.1 0.00082 19.3 5.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 EAY02000.1 - 0.0016 18.5 6.1 0.0044 17.2 6.1 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 EAY02000.1 - 0.035 14.0 8.8 0.081 12.8 8.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EAY02000.1 - 0.047 13.8 9.0 0.12 12.6 9.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EAY02000.1 - 0.29 11.0 7.4 0.53 10.1 7.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EAY02000.1 - 0.32 10.7 10.3 0.031 13.9 5.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EAY02000.1 - 0.69 9.9 10.2 0.13 12.2 4.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 EAY02000.1 - 3 7.6 7.9 10 5.9 7.8 1.9 1 1 0 1 1 1 0 P-11 zinc finger Rhodanese PF00581.20 EAY02002.1 - 0.064 13.8 1.8 0.087 13.4 1.4 1.4 1 1 0 1 1 1 0 Rhodanese-like domain UPF0147 PF03685.13 EAY02002.1 - 0.13 12.3 3.6 0.25 11.4 3.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF2987 PF11205.8 EAY02002.1 - 0.16 11.9 3.5 0.092 12.6 2.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) CC2-LZ PF16516.5 EAY02002.1 - 0.48 10.8 10.9 0.33 11.3 4.2 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Glutaredoxin2_C PF04399.13 EAY02002.1 - 2.1 8.2 6.3 1.9 8.4 1.1 2.1 1 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain LMBR1 PF04791.16 EAY02002.1 - 6.4 5.6 9.1 6.7 5.5 9.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MULE PF10551.9 EAY02004.1 - 6.4e-13 48.9 2.5 8.4e-13 48.6 0.2 2.5 3 0 0 3 3 3 1 MULE transposase domain WRKY PF03106.15 EAY02004.1 - 0.054 13.7 2.1 0.13 12.6 0.7 2.4 1 1 1 2 2 2 0 WRKY DNA -binding domain FAR1 PF03101.15 EAY02006.1 - 0.024 15.3 0.1 0.053 14.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DDE_Tnp_4 PF13359.6 EAY02007.1 - 1.6e-19 70.1 0.0 2.1e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EAY02008.1 - 2.4e-07 30.6 0.1 3.8e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.7 EAY02009.1 - 3.4e-29 101.2 0.6 7.5e-09 36.1 0.1 5.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02009.1 - 1.7e-25 86.3 2.4 0.00012 22.2 0.0 8.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EAY02009.1 - 4.8e-23 80.9 2.7 1.7e-07 31.3 0.0 6.6 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY02009.1 - 3.3e-19 69.0 1.3 0.00098 19.7 0.0 6.6 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY02009.1 - 1.1e-17 63.6 0.8 0.00019 21.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat rve PF00665.26 EAY02010.1 - 3.1e-16 59.7 0.1 1.3e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 EAY02010.1 - 0.0006 19.5 3.3 0.00076 19.2 0.8 2.4 2 1 0 2 2 2 1 Integrase core domain Thioredoxin_2 PF13098.6 EAY02010.1 - 0.0041 17.5 0.4 0.032 14.7 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like domain zf-Sec23_Sec24 PF04810.15 EAY02010.1 - 0.032 14.3 0.6 0.077 13.1 0.6 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Collagen_bind_2 PF12904.7 EAY02011.1 - 0.15 12.1 0.0 3.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase BLM10_mid PF16507.5 EAY02013.1 - 5.6e-10 38.5 9.8 6.7e-06 25.0 1.0 3.7 4 0 0 4 4 4 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EAY02013.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) HEAT PF02985.22 EAY02013.1 - 0.076 13.3 0.0 83 3.9 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat PDEase_I_N PF08499.12 EAY02013.1 - 1.8 8.5 3.9 2.6 8.0 0.0 3.2 3 1 1 4 4 4 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PTR PF12789.7 EAY02014.1 - 8.6e-29 99.4 11.4 8.6e-29 99.4 11.4 2.3 3 0 0 3 3 3 1 Phage tail repeat like DUF3839 PF12943.7 EAY02015.1 - 6.3e-142 471.1 11.1 7.8e-142 470.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY02015.1 - 0.13 12.7 2.8 0.19 12.2 0.4 2.0 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 EAY02015.1 - 1 9.7 5.5 7.5 6.9 0.1 3.5 4 0 0 4 4 4 0 Tup N-terminal KELK PF15796.5 EAY02015.1 - 1.1 9.8 6.6 4.5 7.8 0.3 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KilA-N PF04383.13 EAY02016.1 - 6.8e-18 64.6 0.0 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain zf-RING_9 PF13901.6 EAY02016.1 - 0.062 13.3 0.3 0.066 13.2 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Pox_A32 PF04665.12 EAY02018.1 - 6.5e-06 25.8 1.3 6.5e-06 25.8 1.3 2.0 1 1 1 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EAY02018.1 - 4.4e-05 23.8 0.1 0.00031 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY02018.1 - 9.2e-05 22.2 0.2 0.37 10.5 0.0 2.7 1 1 1 3 3 3 2 IstB-like ATP binding protein ResIII PF04851.15 EAY02018.1 - 0.00016 21.7 2.9 0.00034 20.7 2.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAY02018.1 - 0.00081 19.2 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY02018.1 - 0.0018 18.1 0.7 0.0044 16.8 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAY02018.1 - 0.0055 16.4 1.9 0.024 14.3 0.1 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EAY02018.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAY02018.1 - 0.11 12.0 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAY02018.1 - 0.12 12.8 0.1 0.92 9.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 EAY02018.1 - 0.12 12.5 0.6 1.5 8.8 0.6 2.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain PhoH PF02562.16 EAY02018.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF1827 PF08860.10 EAY02018.1 - 0.52 10.6 4.0 10 6.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF2805 PF10985.8 EAY02018.1 - 0.85 10.0 0.0 0.85 10.0 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2805) DUF573 PF04504.14 EAY02018.1 - 2 9.1 11.3 0.35 11.5 1.3 3.5 3 1 1 4 4 4 0 Protein of unknown function, DUF573 DUF4108 PF13390.6 EAY02019.1 - 2e-64 215.9 6.2 2.2e-64 215.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) bZIP_1 PF00170.21 EAY02020.1 - 0.00084 19.4 4.2 0.00084 19.4 4.2 34.8 13 7 20 35 35 35 13 bZIP transcription factor YabA PF06156.13 EAY02020.1 - 0.003 18.1 11.5 0.003 18.1 11.5 26.9 6 4 22 28 28 28 6 Initiation control protein YabA E2F_TDP PF02319.20 EAY02021.1 - 9.1e-05 22.4 0.7 0.0091 16.0 0.2 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain ChAPs PF09295.10 EAY02022.1 - 1.4e-13 50.6 0.6 9.6e-13 47.9 0.1 2.2 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EAY02022.1 - 0.0099 16.4 0.6 0.2 12.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAY02022.1 - 0.068 13.4 0.2 5.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 EAY02023.1 - 5.1e-36 124.0 0.1 1.2e-35 122.9 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 EAY02023.1 - 1.1e-08 35.1 0.4 4.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EAY02023.1 - 1.1e-08 35.3 0.6 4.6e-08 33.2 0.4 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAY02023.1 - 0.0004 20.6 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAY02023.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 EAY02023.1 - 0.007 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold DDE_Tnp_4 PF13359.6 EAY02023.1 - 0.039 13.6 0.8 16 5.1 0.1 3.4 3 0 0 3 3 3 0 DDE superfamily endonuclease Spc7 PF08317.11 EAY02023.1 - 1.7 7.5 7.2 0.073 11.9 0.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein M60-like_N PF17291.2 EAY02024.1 - 4.2e-19 68.4 0.4 5.9e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 EAY02024.1 - 8.9e-14 51.6 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like E1_FCCH PF16190.5 EAY02024.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain MRP-S33 PF08293.11 EAY02026.1 - 0.014 15.7 0.8 2.1 8.6 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal subunit S27 Mucin PF01456.17 EAY02027.1 - 0.83 9.6 12.6 1.1 9.3 12.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Chromo PF00385.24 EAY02028.1 - 0.00014 21.7 2.0 0.00014 21.7 2.0 3.0 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EAY02028.1 - 0.05 13.6 4.5 0.15 12.1 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Mem_trans PF03547.18 EAY02028.1 - 0.056 11.8 0.2 0.11 10.8 0.2 1.6 1 0 0 1 1 1 0 Membrane transport protein Chibby PF14645.6 EAY02029.1 - 1.6e-07 31.8 0.2 2.6e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Chibby family TSC22 PF01166.18 EAY02029.1 - 2.3 8.6 9.0 1.2 9.5 1.1 2.5 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 EAY02029.1 - 2.7 8.2 9.4 2 8.6 0.5 2.4 2 0 0 2 2 2 0 Basic region leucine zipper FliJ PF02050.16 EAY02031.1 - 0.02 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein FAS_N PF17828.1 EAY02033.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF2939 PF11159.8 EAY02034.1 - 0.022 15.1 0.9 0.035 14.5 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Membralin PF09746.9 EAY02034.1 - 1.5 7.8 3.7 1.6 7.7 3.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 EAY02034.1 - 1.9 8.5 6.8 2.2 8.3 6.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PapD_N PF00345.20 EAY02035.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1043 PF06295.12 EAY02035.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DNA_pol_B_2 PF03175.13 EAY02037.1 - 6.5e-30 104.4 11.6 2.5e-29 102.5 11.6 1.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral T5orf172 PF10544.9 EAY02038.1 - 4.3e-06 27.2 0.2 9.5e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 T5orf172 domain HALZ PF02183.18 EAY02039.1 - 0.027 14.7 2.8 0.027 14.7 2.8 9.3 9 1 1 10 10 10 0 Homeobox associated leucine zipper ATG16 PF08614.11 EAY02039.1 - 8 6.6 95.7 4 7.6 27.6 5.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) RNA_pol_N PF01194.17 EAY02039.1 - 8.2 6.8 6.4 2.7 8.4 0.3 3.5 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Collagen_bind_2 PF12904.7 EAY02040.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF4107 PF13389.6 EAY02041.1 - 6.3e-72 241.0 4.2 8.3e-72 240.6 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAY02043.1 - 4e-129 429.2 8.4 5.1e-129 428.9 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PapD_N PF00345.20 EAY02045.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PadR PF03551.14 EAY02045.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF373 PF04123.13 EAY02046.1 - 0.2 11.1 4.6 0.34 10.3 4.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) YrvL PF14184.6 EAY02046.1 - 2.2 8.4 10.7 0.14 12.3 2.6 2.2 2 0 0 2 2 2 0 Regulatory protein YrvL CRPA PF05745.11 EAY02047.1 - 0.037 14.0 0.3 0.1 12.6 0.3 1.7 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) CRISPR_Cas2 PF09827.9 EAY02047.1 - 0.087 13.0 0.1 0.45 10.7 0.1 2.4 1 1 0 1 1 1 0 CRISPR associated protein Cas2 Guanylate_cyc PF00211.20 EAY02048.1 - 3.2e-41 141.0 0.2 5.9e-41 140.1 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY02048.1 - 4e-07 30.2 1.6 1.1e-06 28.8 1.6 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAY02048.1 - 0.0016 18.5 0.1 0.0033 17.4 0.1 1.5 1 0 0 1 1 1 1 PAS fold Orf78 PF06024.12 EAY02048.1 - 1.2 9.5 7.1 1.1 9.5 0.4 2.6 2 0 0 2 2 2 0 Orf78 (ac78) C9orf72-like PF15019.6 EAY02049.1 - 1.4e-62 211.4 10.1 1.4e-62 211.4 10.1 1.6 2 0 0 2 2 2 1 C9orf72-like protein family DUF4978 PF16349.5 EAY02049.1 - 0.057 13.1 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) Ras PF00071.22 EAY02050.1 - 1.5e-40 138.5 0.6 1.9e-40 138.1 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY02050.1 - 2.2e-29 102.1 0.3 5.4e-29 100.9 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY02050.1 - 2.5e-15 56.4 0.1 3.2e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAY02050.1 - 1.4e-07 31.6 0.2 2.4e-07 30.9 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAY02050.1 - 1e-06 28.3 0.3 1.4e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAY02050.1 - 2.2e-05 24.1 0.1 4.7e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAY02050.1 - 4.6e-05 23.4 0.4 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAY02050.1 - 0.0003 20.3 0.4 0.00045 19.7 0.4 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EAY02050.1 - 0.0008 19.2 0.3 0.063 13.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 EAY02050.1 - 0.0038 16.8 0.1 0.027 14.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EAY02050.1 - 0.0081 15.9 0.2 0.66 9.7 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CM2 PF03021.14 EAY02050.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein TniB PF05621.11 EAY02050.1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MeaB PF03308.16 EAY02050.1 - 0.087 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EAY02050.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EAY02051.1 - 2.8e-56 190.8 0.0 3.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02051.1 - 8.4e-43 146.5 0.0 3.3e-42 144.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAY02051.1 - 0.00069 18.7 0.2 0.0026 16.8 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAY02051.1 - 0.0024 16.7 0.0 0.0055 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 EAY02051.1 - 0.0063 16.2 0.3 0.011 15.4 0.3 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kinase-like PF14531.6 EAY02051.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EAY02052.1 - 6.4e-24 84.7 0.0 7.1e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02052.1 - 9.5e-14 51.3 0.0 1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAY02052.1 - 0.00093 18.1 0.0 0.00099 18.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EAY02052.1 - 0.0054 15.7 0.0 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAY02052.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAY02052.1 - 0.024 13.7 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EAY02052.1 - 0.072 12.4 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DnaJ_C PF01556.18 EAY02053.1 - 1.3e-35 122.6 0.4 1.7e-35 122.3 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAY02053.1 - 5.3e-27 93.7 1.2 8.2e-27 93.1 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EAY02054.1 - 3.7e-46 157.6 0.0 4.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02054.1 - 3.8e-31 108.3 0.0 5.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY02054.1 - 0.0019 17.5 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like BTG PF07742.12 EAY02055.1 - 0.0034 17.2 0.1 0.0047 16.8 0.1 1.2 1 0 0 1 1 1 1 BTG family Glyoxalase_2 PF12681.7 EAY02055.1 - 0.053 13.5 0.0 0.087 12.8 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain LRR_5 PF13306.6 EAY02056.1 - 3e-132 434.6 62.4 4.2e-29 101.1 5.4 6.7 2 2 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02056.1 - 1.9e-13 49.9 8.5 0.0015 18.2 0.7 9.1 6 3 7 13 13 13 6 Leucine rich repeat LRR_4 PF12799.7 EAY02056.1 - 1.6e-05 25.1 7.3 0.0048 17.3 0.3 6.0 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) ECSCR PF15820.5 EAY02056.1 - 0.044 13.6 0.4 0.12 12.2 0.4 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Herpes_gE PF02480.16 EAY02056.1 - 0.08 11.7 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SP_C-Propep PF08999.10 EAY02056.1 - 0.08 12.7 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EVI2A PF05399.11 EAY02056.1 - 0.14 11.7 5.6 0.066 12.8 1.7 2.1 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.6 EAY02056.1 - 0.41 10.5 13.6 0.028 14.3 1.1 2.9 1 1 1 2 2 2 0 TMEM154 protein family FNIP_M PF14637.6 EAY02057.1 - 0.003 17.6 6.6 0.007 16.4 0.7 3.6 2 1 0 2 2 2 1 Folliculin-interacting protein middle domain DUF5564 PF17719.1 EAY02057.1 - 0.012 15.8 0.4 0.049 13.8 0.4 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5564) YjcZ PF13990.6 EAY02057.1 - 0.14 11.5 0.1 0.41 10.0 0.1 1.8 1 0 0 1 1 1 0 YjcZ-like protein DUF745 PF05335.13 EAY02057.1 - 1 9.1 18.7 0.92 9.2 0.4 4.6 4 2 1 5 5 5 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 EAY02057.1 - 2.6 8.1 23.9 3.2 7.8 3.4 5.4 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 EAY02057.1 - 5.3 6.8 19.7 1.8 8.3 1.3 4.5 3 1 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lzipper-MIP1 PF14389.6 EAY02057.1 - 5.3 7.4 16.4 2.1 8.7 0.0 5.9 6 0 0 6 6 6 0 Leucine-zipper of ternary complex factor MIP1 Pkinase PF00069.25 EAY02058.1 - 2e-29 102.8 0.1 2.3e-29 102.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02058.1 - 1.5e-19 70.3 0.0 1.8e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Inhibitor_I24 PF10465.9 EAY02058.1 - 0.0024 17.9 0.1 0.0038 17.2 0.1 1.3 1 0 0 1 1 1 1 PinA peptidase inhibitor YukC PF10140.9 EAY02058.1 - 0.11 11.3 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC HTH_32 PF13565.6 EAY02059.1 - 0.083 13.5 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain F5_F8_type_C PF00754.25 EAY02060.1 - 2.6e-06 27.6 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF3149 PF11346.8 EAY02061.1 - 0.061 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DDE_1 PF03184.19 EAY02062.1 - 4.9e-12 45.8 0.0 6.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EAY02063.1 - 5.4e-16 58.7 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MCR_alpha_N PF02745.15 EAY02064.1 - 0.38 10.1 1.1 0.74 9.1 0.6 1.6 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Syndecan PF01034.20 EAY02065.1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EAY02065.1 - 0.00043 20.5 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 Glycophorin A Amnionless PF14828.6 EAY02065.1 - 0.0041 16.0 0.0 0.0051 15.7 0.0 1.1 1 0 0 1 1 1 1 Amnionless Orf78 PF06024.12 EAY02065.1 - 0.011 16.0 1.9 0.012 15.9 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF3377 PF11857.8 EAY02065.1 - 0.028 14.3 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) UL45 PF05473.12 EAY02065.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like NEMP PF10225.9 EAY02065.1 - 0.044 13.4 0.2 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 NEMP family EphA2_TM PF14575.6 EAY02065.1 - 0.088 13.7 0.1 0.19 12.6 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 EAY02065.1 - 0.099 13.1 0.6 0.25 11.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF4834 PF16118.5 EAY02065.1 - 0.11 13.4 3.2 0.13 13.3 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Phage_holin_2_3 PF16080.5 EAY02065.1 - 0.15 11.9 0.3 0.15 11.9 0.3 1.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 TMEM154 PF15102.6 EAY02065.1 - 0.18 11.7 7.0 0.4 10.6 6.4 2.0 1 1 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.6 EAY02065.1 - 0.39 10.6 0.1 0.39 10.6 0.1 1.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SIT PF15330.6 EAY02065.1 - 0.8 10.2 2.9 0.72 10.3 0.1 2.4 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Orf78 PF06024.12 EAY02067.1 - 1.7e-06 28.3 0.1 2.8e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) TMEM52 PF14979.6 EAY02067.1 - 0.00032 20.6 0.6 0.0088 16.0 0.0 2.1 2 0 0 2 2 2 1 Transmembrane 52 Rax2 PF12768.7 EAY02067.1 - 0.00033 20.2 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 EAY02067.1 - 0.00041 20.3 8.4 0.00058 19.8 8.3 1.6 1 1 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EAY02067.1 - 0.0062 16.4 2.8 0.011 15.5 2.7 1.5 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EAY02067.1 - 0.0064 16.2 4.0 0.012 15.3 4.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.6 EAY02067.1 - 0.0092 16.2 1.9 0.0092 16.2 1.9 1.6 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.11 EAY02067.1 - 0.011 16.0 2.1 0.011 16.0 2.1 2.3 3 0 0 3 3 2 0 Chordopoxvirus A13L protein Sigma_reg_N PF13800.6 EAY02067.1 - 0.015 15.6 1.2 0.032 14.5 1.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3827 PF12877.7 EAY02067.1 - 0.025 13.0 0.1 0.034 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CD34_antigen PF06365.12 EAY02067.1 - 0.032 13.8 0.2 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 EAY02067.1 - 0.034 14.2 3.2 0.057 13.5 3.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TALPID3 PF15324.6 EAY02067.1 - 0.043 11.5 8.8 0.046 11.4 8.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF4834 PF16118.5 EAY02067.1 - 0.053 14.5 1.0 0.053 14.5 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EAY02067.1 - 0.055 14.4 0.6 0.13 13.1 0.3 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 EAY02067.1 - 0.059 13.8 0.2 0.15 12.5 0.2 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Chordopox_A33R PF05966.12 EAY02067.1 - 0.081 12.2 1.3 0.1 11.9 1.3 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Syndecan PF01034.20 EAY02067.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3377 PF11857.8 EAY02067.1 - 0.83 9.6 4.9 0.69 9.9 3.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4690 PF15756.5 EAY02067.1 - 2.5 8.8 8.8 0.41 11.3 0.5 2.6 1 1 2 3 3 3 0 Small Novel Rich in Cartilage PTR PF12789.7 EAY02068.1 - 1.5e-25 89.0 23.2 1.5e-23 82.6 6.1 4.8 4 1 0 4 4 4 2 Phage tail repeat like DUF4116 PF13475.6 EAY02068.1 - 0.069 12.9 0.1 0.069 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF240 PF03086.14 EAY02068.1 - 0.18 11.7 3.7 1.7 8.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF4795 PF16043.5 EAY02068.1 - 0.58 9.7 23.7 0.16 11.6 1.8 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) DUF1493 PF07377.12 EAY02069.1 - 0.033 14.7 0.7 0.069 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY02070.1 - 0.063 13.9 4.9 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY02071.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP Ank_2 PF12796.7 EAY02073.1 - 9.9e-14 51.7 2.0 7.1e-06 26.5 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02073.1 - 5e-09 36.5 3.0 0.0031 18.0 0.7 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02073.1 - 3.9e-07 29.9 9.6 0.39 11.4 0.2 5.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EAY02073.1 - 0.16 12.4 0.5 65 4.0 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02074.1 - 2.4e-13 50.5 6.2 0.0022 18.5 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02074.1 - 1.9e-08 33.9 3.8 0.13 12.9 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EAY02074.1 - 5.9e-08 33.1 2.7 0.017 15.7 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY02074.1 - 0.013 15.9 0.8 4.6 7.9 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 EAY02074.1 - 0.15 12.4 0.1 41 4.6 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Herpes_TK_C PF08465.10 EAY02075.1 - 4.2e-07 29.6 8.0 5.8 6.7 0.0 5.2 5 0 0 5 5 5 3 Thymidine kinase from Herpesvirus C-terminal Ub-RnfH PF03658.14 EAY02075.1 - 6.8e-07 29.6 0.1 9.7 6.7 0.0 5.0 5 0 0 5 5 5 1 RnfH family Ubiquitin ArsC PF03960.15 EAY02075.1 - 0.00025 21.0 1.5 18 5.5 0.0 4.7 5 0 0 5 5 5 0 ArsC family SelB-wing_2 PF09106.11 EAY02075.1 - 0.00052 20.2 1.2 2.8 8.2 0.0 3.5 4 1 0 4 4 3 2 Elongation factor SelB, winged helix RNase_J_C PF17770.1 EAY02075.1 - 0.0021 19.0 0.2 5.6 8.1 0.1 3.9 1 1 3 4 4 4 1 Ribonuclease J C-terminal domain Integrin_b_cyt PF08725.11 EAY02075.1 - 0.0034 17.0 0.0 34 4.2 0.0 3.9 4 0 0 4 4 4 0 Integrin beta cytoplasmic domain DUF4378 PF14309.6 EAY02075.1 - 0.0081 16.6 0.0 2.4 8.5 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4378) ATP_bind_3 PF01171.20 EAY02075.1 - 0.0081 15.9 0.1 2.8 7.7 0.0 3.2 1 1 4 5 5 5 1 PP-loop family MerT PF02411.15 EAY02075.1 - 0.02 14.9 0.5 38 4.3 0.0 4.2 2 1 3 5 5 5 0 MerT mercuric transport protein REV1_C PF16727.5 EAY02075.1 - 0.023 15.1 0.6 8.9 6.8 0.1 3.4 1 1 3 4 4 4 0 DNA repair protein REV1 C-terminal domain DUF768 PF05589.11 EAY02075.1 - 0.024 14.6 0.1 12 6.0 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF768) Slx4 PF09494.10 EAY02075.1 - 0.025 14.5 0.0 12 6.0 0.0 2.6 1 1 1 2 2 2 0 Slx4 endonuclease TetR_C_26 PF17934.1 EAY02075.1 - 0.033 14.5 5.9 78 3.7 0.0 4.8 3 1 2 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Vhr1 PF04001.13 EAY02075.1 - 0.033 14.5 0.4 40 4.6 0.0 3.6 4 0 0 4 4 4 0 Transcription factor Vhr1 APS_kinase PF01583.20 EAY02075.1 - 0.045 13.6 0.2 11 5.9 0.0 3.2 1 1 2 3 3 3 0 Adenylylsulphate kinase UBA_2 PF08587.11 EAY02075.1 - 0.17 12.0 0.0 65 3.7 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) SOGA PF11365.8 EAY02075.1 - 0.69 11.1 7.0 1.2e+02 3.9 0.1 4.0 4 0 0 4 4 4 0 Protein SOGA ArfGap PF01412.18 EAY02076.1 - 1.9e-31 108.6 0.3 1.9e-31 108.6 0.3 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EAY02076.1 - 3.6e-10 40.0 9.6 5.8e-10 39.3 9.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EAY02076.1 - 3.9e-08 33.8 0.1 9.6e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 EAY02076.1 - 1.8e-05 25.2 0.0 5.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02076.1 - 0.02 15.4 0.0 0.47 11.0 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Sigma70_ner PF04546.13 EAY02076.1 - 0.071 13.0 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Vps5 PF09325.10 EAY02076.1 - 0.1 12.1 2.9 0.22 11.1 0.2 2.5 2 1 1 3 3 3 0 Vps5 C terminal like APAF1_C PF17908.1 EAY02076.1 - 0.17 11.9 4.5 0.32 11.0 2.0 2.3 1 1 1 2 2 2 0 APAF-1 helical domain Pox_Ag35 PF03286.14 EAY02076.1 - 0.18 11.6 1.4 0.6 9.9 0.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CoatB PF10389.9 EAY02077.1 - 8.1 6.4 11.9 0.16 11.8 2.8 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B Tetraspanin PF00335.20 EAY02079.1 - 1.8e-26 93.3 15.3 2.3e-26 92.9 15.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2569 PF10754.9 EAY02079.1 - 0.00031 21.2 10.7 0.083 13.3 9.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2569) Adeno_E3_CR2 PF02439.15 EAY02079.1 - 0.0041 16.8 2.7 0.0041 16.8 2.7 3.9 4 0 0 4 4 3 1 Adenovirus E3 region protein CR2 Cyt_bd_oxida_II PF02322.15 EAY02079.1 - 0.0042 16.5 2.7 0.028 13.8 1.6 2.0 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II Orf78 PF06024.12 EAY02079.1 - 0.0075 16.6 0.2 0.0075 16.6 0.2 4.2 2 1 1 3 3 2 1 Orf78 (ac78) Podoplanin PF05808.11 EAY02079.1 - 0.0089 16.2 0.1 0.0089 16.2 0.1 2.4 3 0 0 3 3 2 1 Podoplanin TMEM154 PF15102.6 EAY02079.1 - 0.0089 15.9 0.1 0.0089 15.9 0.1 3.6 3 1 1 4 4 4 1 TMEM154 protein family TssN PF17555.2 EAY02079.1 - 0.011 15.2 11.9 0.011 15.1 9.5 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN ETRAMP PF09716.10 EAY02079.1 - 0.025 14.6 1.4 0.025 14.6 1.4 3.1 4 0 0 4 4 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1180 PF06679.12 EAY02079.1 - 0.043 14.2 7.8 0.22 11.9 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DAG1 PF05454.11 EAY02079.1 - 0.046 13.1 0.0 0.046 13.1 0.0 2.4 2 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Golgin_A5 PF09787.9 EAY02079.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5362 PF17319.2 EAY02079.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.9 2 1 1 3 3 2 0 Family of unknown function (DUF5362) DUF1345 PF07077.11 EAY02079.1 - 0.16 11.6 3.6 0.59 9.8 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) CbiM PF01891.16 EAY02079.1 - 0.4 10.5 7.5 0.12 12.2 4.1 1.7 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region DUF2981 PF11200.8 EAY02079.1 - 0.99 9.1 7.3 0.97 9.1 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) DUF4131 PF13567.6 EAY02079.1 - 1.4 8.5 3.1 1.6 8.4 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) S1FA PF04689.13 EAY02079.1 - 1.8 8.7 0.0 1.8 8.7 0.0 3.7 4 0 0 4 4 4 0 DNA binding protein S1FA SieB PF14163.6 EAY02079.1 - 2.6 7.5 15.6 1.1 8.7 6.9 3.0 2 1 1 3 3 3 0 Super-infection exclusion protein B TctB PF07331.11 EAY02079.1 - 3.8 7.8 10.5 17 5.6 10.6 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.9 EAY02079.1 - 4.4 6.0 19.1 3.4 6.3 0.0 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF3447 PF11929.8 EAY02080.1 - 0.0063 16.4 0.8 0.0063 16.4 0.8 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY02080.1 - 0.0084 16.7 0.1 0.25 11.9 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) CD34_antigen PF06365.12 EAY02081.1 - 0.021 14.4 0.2 0.023 14.3 0.2 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family ABG_transport PF03806.13 EAY02081.1 - 0.027 12.7 0.0 0.027 12.7 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family Tetraspanin PF00335.20 EAY02082.1 - 6.8e-21 75.0 16.5 8.6e-21 74.7 16.5 1.1 1 0 0 1 1 1 1 Tetraspanin family ETRAMP PF09716.10 EAY02082.1 - 9.1e-05 22.5 2.7 0.3 11.2 0.0 2.8 1 1 2 3 3 3 2 Malarial early transcribed membrane protein (ETRAMP) ECF_trnsprt PF12822.7 EAY02082.1 - 0.0023 18.1 17.6 0.36 10.9 0.2 2.1 2 0 0 2 2 2 2 ECF transporter, substrate-specific component Mid2 PF04478.12 EAY02082.1 - 0.0051 16.7 0.2 0.0051 16.7 0.2 3.5 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor ABC2_membrane_2 PF12679.7 EAY02082.1 - 0.013 14.7 4.1 0.025 13.9 4.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2569 PF10754.9 EAY02082.1 - 0.022 15.2 13.2 0.35 11.3 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Wzy_C PF04932.15 EAY02082.1 - 0.035 13.7 4.4 0.43 10.2 4.4 2.3 1 1 0 1 1 1 0 O-Antigen ligase DUF2981 PF11200.8 EAY02082.1 - 0.06 13.1 6.1 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) TssN PF17555.2 EAY02082.1 - 0.15 11.4 14.4 0.18 11.2 10.4 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF202 PF02656.15 EAY02082.1 - 0.37 11.3 4.0 14 6.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TctB PF07331.11 EAY02082.1 - 0.48 10.7 8.4 0.93 9.8 6.4 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2975 PF11188.8 EAY02082.1 - 0.54 10.1 12.7 0.39 10.6 9.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) MTABC_N PF16185.5 EAY02082.1 - 1.5 8.3 10.8 1 8.8 8.6 1.8 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Serinc PF03348.15 EAY02082.1 - 1.8 7.4 19.8 1.7 7.4 14.2 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF898 PF05987.13 EAY02082.1 - 2.4 7.1 7.7 1.4 7.9 3.9 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) SieB PF14163.6 EAY02082.1 - 3.8 7.0 16.2 6.5 6.2 11.6 2.6 2 1 0 2 2 2 0 Super-infection exclusion protein B DUF4231 PF14015.6 EAY02082.1 - 6.7 7.2 8.2 37 4.9 5.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Raptor_N PF14538.6 EAY02083.1 - 3e-33 114.8 0.1 1e-32 113.1 0.1 2.0 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Myb_DNA-binding PF00249.31 EAY02084.1 - 4.9e-26 90.7 3.3 8.8e-16 57.8 1.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02084.1 - 2.2e-20 72.6 5.3 8.5e-15 54.8 1.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY02084.1 - 0.00029 20.8 3.5 0.0099 15.9 0.1 3.1 1 1 3 4 4 4 1 SLIDE Myb_DNA-bind_7 PF15963.5 EAY02084.1 - 0.0033 17.3 5.9 0.027 14.4 0.5 2.4 1 1 1 2 2 2 2 Myb DNA-binding like IlvC PF01450.19 EAY02084.1 - 0.0066 16.7 0.6 0.015 15.6 0.2 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Gemini_AL1 PF00799.20 EAY02084.1 - 0.029 14.7 0.2 0.081 13.3 0.1 1.8 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain Myb_DNA-bind_4 PF13837.6 EAY02084.1 - 0.033 14.5 9.1 0.076 13.4 0.8 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MRC1 PF09444.10 EAY02084.1 - 0.047 14.2 2.3 0.19 12.3 0.8 2.0 1 1 1 2 2 2 0 MRC1-like domain Myb_DNA-bind_2 PF08914.11 EAY02084.1 - 0.068 13.4 0.2 0.3 11.3 0.1 2.2 2 1 0 2 2 2 0 Rap1 Myb domain RibD_C PF01872.17 EAY02085.1 - 1.2e-13 51.4 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Cupin_2 PF07883.11 EAY02085.1 - 2.7e-09 36.6 0.8 9.8e-09 34.8 0.3 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EAY02085.1 - 0.019 14.5 0.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 Cupin AraC_binding PF02311.19 EAY02085.1 - 0.096 12.6 0.3 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain Actin PF00022.19 EAY02086.1 - 5.5e-139 463.3 0.0 2.1e-138 461.4 0.0 1.7 1 1 0 1 1 1 1 Actin MIT_C PF16565.5 EAY02086.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Choline_transpo PF04515.12 EAY02087.1 - 4.2e-23 82.1 25.8 4.2e-23 82.1 25.8 3.2 1 1 2 3 3 3 1 Plasma-membrane choline transporter ubiquitin PF00240.23 EAY02088.1 - 1.9e-11 43.6 0.0 4.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF3907 PF13047.6 EAY02088.1 - 0.0075 16.2 0.1 0.022 14.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3907) DUF2407 PF10302.9 EAY02088.1 - 0.059 13.9 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Myb_DNA-binding PF00249.31 EAY02089.1 - 1.1e-20 73.5 3.3 1.8e-09 37.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02089.1 - 2.8e-16 59.5 3.1 7.1e-08 32.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY02089.1 - 2.4e-06 27.4 1.6 0.00026 20.8 0.4 3.1 2 2 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 EAY02089.1 - 0.0013 18.7 0.7 0.64 10.1 0.1 2.5 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAY02089.1 - 0.0019 18.4 1.0 0.0044 17.2 0.3 2.0 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAY02089.1 - 0.08 13.3 5.2 0.27 11.7 1.3 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain zf-C2H2_12 PF18658.1 EAY02089.1 - 0.17 11.4 2.3 0.45 10.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger C2H2-type TMEM154 PF15102.6 EAY02090.1 - 0.0037 17.2 1.6 0.013 15.4 1.6 1.9 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 EAY02090.1 - 0.24 11.8 0.3 0.5 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2116 PF09889.9 EAY02090.1 - 0.29 11.2 1.5 0.72 9.9 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Syndecan PF01034.20 EAY02090.1 - 0.3 11.0 2.2 0.63 10.0 2.2 1.4 1 0 0 1 1 1 0 Syndecan domain UPF0242 PF06785.11 EAY02091.1 - 0.0067 16.6 17.2 0.0067 16.6 17.2 4.4 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 EAY02091.1 - 0.088 12.7 0.3 0.088 12.7 0.3 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MtrG PF04210.13 EAY02091.1 - 2.5 8.0 8.7 0.42 10.5 0.7 3.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fez1 PF06818.15 EAY02091.1 - 8.9 6.7 48.3 3.3 8.1 18.7 3.4 1 1 1 2 2 2 0 Fez1 Myb_DNA-binding PF00249.31 EAY02092.1 - 3.4e-21 75.1 5.1 3.2e-11 43.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02092.1 - 1.8e-18 66.5 8.9 1.1e-14 54.4 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY02092.1 - 0.00019 21.3 2.2 0.0019 18.1 0.2 2.4 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EAY02092.1 - 0.0078 16.2 0.2 2.7 8.0 0.0 2.8 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EAY02092.1 - 0.034 14.2 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RAMP4 PF06624.12 EAY02092.1 - 0.048 13.7 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 IRF PF00605.17 EAY02092.1 - 0.095 13.0 4.4 0.5 10.7 2.5 2.2 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor Myb_DNA-bind_4 PF13837.6 EAY02092.1 - 0.5 10.8 5.5 8 6.9 0.1 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain 3D PF06725.11 EAY02093.1 - 2.4e-08 34.0 0.1 4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 3D domain Lactamase_B_2 PF12706.7 EAY02094.1 - 4.3e-16 59.0 0.0 8e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAY02094.1 - 5.7e-06 26.5 0.1 1e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1181 PF06680.11 EAY02094.1 - 0.0019 18.0 0.1 0.0034 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1181) Lactamase_B_4 PF13691.6 EAY02095.1 - 2e-12 46.6 0.0 3.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease PSP PF04046.16 EAY02100.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY02101.1 - 0.032 14.7 4.7 11 7.2 0.2 3.5 3 1 0 3 3 3 0 TMP repeat Phage_fiber PF03335.13 EAY02103.1 - 7.2 7.1 8.1 18 5.8 1.8 2.7 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3839 PF12943.7 EAY02104.1 - 1.1e-152 506.4 16.3 1.4e-152 506.1 16.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY02104.1 - 0.049 14.1 2.3 0.16 12.4 0.4 2.1 2 0 0 2 2 2 0 Fez1 NTP_transf_6 PF06042.11 EAY02104.1 - 0.05 13.5 2.1 0.12 12.3 1.0 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY02104.1 - 1.5 9.3 6.3 2 8.9 0.3 3.2 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T5orf172 PF10544.9 EAY02105.1 - 1.1e-05 25.9 0.2 3e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 T5orf172 domain Lectin_legB PF00139.19 EAY02105.1 - 0.00074 19.1 0.1 0.095 12.2 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Ank_2 PF12796.7 EAY02106.1 - 3.4e-50 168.6 17.3 2e-16 60.3 0.1 5.5 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02106.1 - 2.7e-49 164.9 11.4 2.3e-11 44.0 0.1 8.2 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02106.1 - 6.6e-36 121.9 3.1 1e-09 38.5 0.1 7.2 2 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02106.1 - 5.8e-35 115.4 6.7 0.00035 20.8 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat DUF3447 PF11929.8 EAY02106.1 - 2.1e-25 88.5 9.3 2.1e-25 88.5 9.3 5.0 5 1 2 7 7 7 1 Domain of unknown function (DUF3447) Ank PF00023.30 EAY02106.1 - 5.2e-23 80.4 7.0 0.061 13.8 0.1 9.4 10 1 0 10 10 10 5 Ankyrin repeat Amidinotransf PF02274.17 EAY02106.1 - 0.083 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Amidinotransferase Lantibiotic_a PF14867.6 EAY02106.1 - 0.089 12.5 0.5 0.31 10.8 0.5 1.9 2 0 0 2 2 2 0 Lantibiotic alpha DnaB_2 PF07261.11 EAY02106.1 - 0.23 11.2 3.1 7 6.5 0.1 3.6 3 1 0 3 3 3 0 Replication initiation and membrane attachment LRR_5 PF13306.6 EAY02107.1 - 1.1e-108 358.4 76.8 5e-23 81.4 5.1 7.3 3 2 3 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02107.1 - 3e-35 119.8 12.9 0.00023 20.9 0.0 10.5 8 3 3 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EAY02107.1 - 5.8e-11 42.5 27.8 0.49 10.9 0.1 10.8 7 2 5 12 12 12 9 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EAY02108.1 - 1.9e-57 191.8 23.5 4.9e-12 46.3 0.7 8.7 5 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02108.1 - 3.3e-41 139.1 9.4 1.8e-09 37.9 0.2 11.0 6 5 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02108.1 - 8.6e-33 112.0 12.6 5.9e-06 26.4 0.4 10.7 8 2 2 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02108.1 - 5.8e-31 103.1 15.5 0.022 15.3 0.1 13.7 15 0 0 15 15 15 8 Ankyrin repeat Ank PF00023.30 EAY02108.1 - 1.4e-19 69.6 19.5 0.025 15.0 0.0 10.6 12 0 0 12 12 12 6 Ankyrin repeat Malt_amylase_C PF16657.5 EAY02108.1 - 0.79 9.9 3.2 1.7e+02 2.4 0.0 6.0 4 1 5 9 9 9 0 Maltogenic Amylase, C-terminal domain DUF3447 PF11929.8 EAY02108.1 - 7.2 6.6 13.4 11 6.0 0.4 5.2 6 1 0 6 6 6 0 Domain of unknown function (DUF3447) L31 PF09784.9 EAY02109.1 - 0.12 12.8 1.9 0.25 11.8 0.1 2.4 1 1 2 3 3 3 0 Mitochondrial ribosomal protein L31 DUF3073 PF11273.8 EAY02110.1 - 0.18 12.6 0.0 0.32 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF4107 PF13389.6 EAY02111.1 - 2.2e-71 239.3 3.1 3.2e-71 238.7 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF3839 PF12943.7 EAY02115.1 - 9.1e-76 254.5 6.3 1.1e-75 254.2 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Fez1 PF06818.15 EAY02115.1 - 0.058 13.8 0.2 0.068 13.6 0.2 1.1 1 0 0 1 1 1 0 Fez1 JMY PF15871.5 EAY02116.1 - 0.041 13.2 0.4 0.067 12.5 0.4 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF5065 PF16723.5 EAY02116.1 - 1.3 9.1 5.0 13 5.8 0.9 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF5065) DNA_pol_B_2 PF03175.13 EAY02117.1 - 1.2e-08 34.2 0.8 2.6e-08 33.2 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Lac_bphage_repr PF06543.12 EAY02117.1 - 0.14 12.2 0.0 0.97 9.5 0.0 2.2 1 1 1 2 2 2 0 Lactococcus bacteriophage repressor PapD_N PF00345.20 EAY02118.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain FAS_N PF17828.1 EAY02119.1 - 0.0078 16.2 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Trypan_PARP PF05887.11 EAY02120.1 - 0.042 13.8 8.4 0.067 13.2 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPS2_interact PF15784.5 EAY02121.1 - 0.017 15.6 0.2 0.02 15.3 0.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RIC3 PF15361.6 EAY02121.1 - 0.035 14.5 2.1 0.035 14.5 2.1 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Myb_DNA-binding PF00249.31 EAY02122.1 - 2e-26 91.9 0.3 3.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02122.1 - 4.2e-18 65.3 0.8 1.3e-10 41.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY02122.1 - 1.6e-05 24.7 5.3 0.0002 21.2 0.4 2.9 2 2 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EAY02122.1 - 6.5e-05 22.9 0.1 0.08 13.0 0.0 2.6 1 1 1 2 2 2 2 SLIDE F5_F8_type_C PF00754.25 EAY02123.1 - 2.3e-05 24.5 0.0 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 EAY02124.1 - 3.4e-07 30.4 0.1 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain NTR2 PF15458.6 EAY02124.1 - 0.24 10.9 2.4 2.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Chitin_bind_4 PF00379.23 EAY02124.1 - 0.81 10.3 3.9 4.2 8.0 0.4 3.0 3 0 0 3 3 3 0 Insect cuticle protein U-box PF04564.15 EAY02125.1 - 0.023 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 U-box domain DUF3580 PF12117.8 EAY02125.1 - 0.29 11.4 3.4 0.67 10.2 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) SHIPPO-rpt PF07004.12 EAY02127.1 - 1.6e-16 60.3 49.1 0.013 16.4 1.3 11.0 10 1 0 10 10 10 8 Sperm-tail PG-rich repeat IL17R_D_N PF16742.5 EAY02128.1 - 0.05 13.7 0.3 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 N-terminus of interleukin 17 receptor D Pcc1 PF09341.10 EAY02129.1 - 0.0015 18.6 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 FlaG PF03646.15 EAY02129.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 FlaG protein SAPIS-gp6 PF16722.5 EAY02129.1 - 0.17 12.3 0.5 1.2 9.6 0.1 2.0 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus PH_TFIIH PF08567.11 EAY02130.1 - 0.045 14.1 1.0 2.5 8.5 0.3 2.2 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain Tudor_3 PF18115.1 EAY02131.1 - 0.11 12.4 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain SWIM PF04434.17 EAY02133.1 - 7e-06 25.6 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger HCV_NS1 PF01560.17 EAY02133.1 - 0.057 12.1 0.1 0.077 11.7 0.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 HBD PF18534.1 EAY02133.1 - 0.096 12.8 0.6 18 5.6 0.0 2.5 1 1 1 2 2 2 0 Helical bundle domain DUF4107 PF13389.6 EAY02134.1 - 2.3e-66 222.9 13.0 1.1e-64 217.5 13.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAY02134.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta DUF3839 PF12943.7 EAY02135.1 - 2.1e-158 525.1 14.3 2.7e-158 524.7 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) DUF2408 PF10303.9 EAY02135.1 - 0.13 12.9 4.9 0.23 12.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KELK PF15796.5 EAY02135.1 - 0.57 10.7 3.5 4.9 7.7 0.3 2.9 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GPS2_interact PF15784.5 EAY02138.1 - 0.045 14.2 0.4 0.056 13.9 0.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY02138.1 - 0.096 11.7 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDR PF08841.10 EAY02139.1 - 0.18 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Gly-zipper_Omp PF13488.6 EAY02140.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAY02140.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAY02140.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAY02140.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY02140.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Gly-zipper_Omp PF13488.6 EAY02142.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAY02142.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAY02142.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAY02142.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY02142.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif LRR_6 PF13516.6 EAY02144.1 - 0.13 12.4 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 Leucine Rich repeat Gly-zipper_Omp PF13488.6 EAY02146.1 - 0.01 15.8 9.0 0.01 15.8 9.0 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAY02146.1 - 0.31 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY02146.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pkinase PF00069.25 EAY02147.1 - 3.1e-47 161.2 0.0 3.7e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02147.1 - 4.1e-25 88.6 0.0 5.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY02147.1 - 1e-07 31.6 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Aldo_ket_red PF00248.21 EAY02148.1 - 1.2e-44 152.8 0.0 2.3e-44 151.7 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EAY02148.1 - 0.016 15.1 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Development and cell death domain Myb_DNA-binding PF00249.31 EAY02149.1 - 1e-28 99.3 6.8 6.3e-14 51.9 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02149.1 - 4.4e-24 84.5 1.0 1.6e-12 47.5 0.7 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAY02149.1 - 0.00074 19.4 0.7 0.011 15.6 1.6 2.4 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAY02149.1 - 0.0013 18.9 0.4 0.0013 18.9 0.4 2.6 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EAY02149.1 - 3.7 7.7 7.3 38 4.4 0.1 3.5 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain SIN1 PF05422.12 EAY02151.1 - 0.028 15.0 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF438 PF04282.13 EAY02153.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) DEAD PF00270.29 EAY02157.1 - 9e-05 22.3 0.0 0.00055 19.7 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EAY02157.1 - 0.021 14.4 0.3 0.021 14.4 0.3 2.8 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain RnlB_antitoxin PF15933.5 EAY02157.1 - 0.98 9.8 5.2 5.3 7.4 0.1 3.6 3 0 0 3 3 3 0 Antitoxin to bacterial toxin RNase LS or RnlA DNTTIP1_dimer PF18192.1 EAY02157.1 - 3 8.3 4.9 1.8 8.9 0.1 3.0 3 1 1 4 4 4 0 DNTTIP1 dimerisation domain DUF2451 PF10474.9 EAY02158.1 - 0.04 13.7 0.6 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) MTHFR_C PF12225.8 EAY02158.1 - 0.04 13.6 1.0 0.088 12.5 1.0 1.6 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal SNARE PF05739.19 EAY02159.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.4 2 0 0 2 2 2 0 SNARE domain PTRF_SDPR PF15237.6 EAY02160.1 - 0.0031 17.2 2.0 0.0037 16.9 2.0 1.1 1 0 0 1 1 1 1 PTRF/SDPR family TMEM52 PF14979.6 EAY02160.1 - 0.026 14.4 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane 52 DUF4834 PF16118.5 EAY02160.1 - 0.032 15.2 0.1 0.055 14.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF948 PF06103.11 EAY02160.1 - 0.039 14.2 0.1 0.076 13.3 0.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EphA2_TM PF14575.6 EAY02160.1 - 0.23 12.3 1.7 0.38 11.7 1.7 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain O-antigen_lig PF13425.6 EAY02160.1 - 0.58 8.9 3.5 0.88 8.3 3.5 1.3 1 1 0 1 1 1 0 O-antigen ligase like membrane protein LSR PF05624.14 EAY02160.1 - 0.67 10.0 10.9 1 9.4 10.9 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Bestrophin PF01062.21 EAY02161.1 - 0.03 13.7 0.8 0.069 12.5 0.0 2.0 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF2207 PF09972.9 EAY02161.1 - 0.041 12.6 5.5 0.25 10.1 2.2 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) LptF_LptG PF03739.14 EAY02161.1 - 0.11 11.3 3.0 0.71 8.7 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG PhoLip_ATPase_C PF16212.5 EAY02162.1 - 8.7e-64 215.6 27.9 8.7e-64 215.6 27.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EAY02162.1 - 6.2e-17 62.6 0.0 8.3e-11 42.6 0.1 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAY02162.1 - 2.4e-10 40.2 0.0 2.4e-10 40.2 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAY02162.1 - 2e-08 34.2 0.0 1.7e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAY02162.1 - 0.0012 18.6 0.1 0.0039 17.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MatE PF01554.18 EAY02163.1 - 4.1e-18 65.5 5.4 4.1e-18 65.5 5.4 1.5 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EAY02163.1 - 4 7.5 18.9 0.82 9.7 6.5 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EAY02164.1 - 8.2e-12 45.1 4.1 8.2e-12 45.1 4.1 1.6 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EAY02164.1 - 8.7e-05 22.6 5.6 8.7e-05 22.6 5.6 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain DUF4457 PF14652.6 EAY02165.1 - 3.1e-10 39.8 1.4 1.2e-09 37.9 0.7 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Orthoreo_P10 PF07204.11 EAY02166.1 - 0.00088 19.2 0.9 0.0017 18.3 0.2 1.8 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 EAY02166.1 - 0.0012 19.1 0.2 0.0022 18.3 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Synaptobrevin PF00957.21 EAY02166.1 - 0.027 14.3 0.2 0.053 13.3 0.2 1.5 1 0 0 1 1 1 0 Synaptobrevin TMEM154 PF15102.6 EAY02166.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 EAY02166.1 - 0.11 13.4 0.1 0.24 12.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCF PF02404.15 EAY02167.1 - 0.0013 18.1 5.7 0.019 14.3 0.8 2.6 2 0 0 2 2 2 2 Stem cell factor DUF2990 PF11693.8 EAY02167.1 - 0.022 14.9 0.2 0.21 11.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) Insulin_TMD PF17870.1 EAY02167.1 - 0.041 14.0 3.3 0.1 12.7 3.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2371 PF10177.9 EAY02167.1 - 0.045 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) MHC2-interact PF09307.10 EAY02167.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 CLIP, MHC2 interacting SKA2 PF16740.5 EAY02167.1 - 0.095 12.5 0.0 7.3 6.4 0.0 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 SKG6 PF08693.10 EAY02167.1 - 0.097 12.1 5.3 0.17 11.3 5.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M56 PF05569.11 EAY02167.1 - 0.1 11.8 0.7 0.17 11.0 0.7 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 SecE PF00584.20 EAY02167.1 - 0.24 11.4 4.7 1.1 9.3 3.7 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Focal_AT PF03623.13 EAY02167.1 - 1.7 8.7 6.3 0.59 10.1 0.2 3.2 4 0 0 4 4 4 0 Focal adhesion targeting region PQ-loop PF04193.14 EAY02168.1 - 8.5e-08 31.9 5.2 1.2e-06 28.2 0.3 3.7 4 0 0 4 4 4 2 PQ loop repeat DUF3323 PF11796.8 EAY02169.1 - 0.054 13.4 0.4 0.067 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) WD40 PF00400.32 EAY02170.1 - 5.3e-26 90.4 18.9 7.7e-08 32.9 3.2 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY02170.1 - 1.5e-10 41.2 0.0 0.32 11.3 0.0 6.2 4 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAY02170.1 - 0.016 14.2 0.0 1 8.2 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5014 PF16406.5 EAY02170.1 - 0.036 14.3 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5014) Nbas_N PF15492.6 EAY02170.1 - 0.091 12.1 0.1 0.47 9.8 0.1 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EAY02170.1 - 0.15 12.1 10.0 5 7.2 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PEPCK_GTP PF00821.18 EAY02171.1 - 8.4e-160 531.4 0.1 3e-159 529.6 0.3 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 EAY02171.1 - 5.6e-101 336.7 0.0 7.6e-101 336.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain IU_nuc_hydro PF01156.19 EAY02172.1 - 3.8e-65 220.4 0.0 4.5e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HSP70 PF00012.20 EAY02173.1 - 1.1e-10 40.4 1.4 1.2e-10 40.2 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein ExsD PF16806.5 EAY02173.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Antiactivator protein ExsD Syntaxin_2 PF14523.6 EAY02174.1 - 0.00075 19.8 2.8 0.1 13.0 1.4 2.5 2 1 0 2 2 2 2 Syntaxin-like protein KTI12 PF08433.10 EAY02174.1 - 0.022 14.2 0.2 0.029 13.8 0.2 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 zf-C2HE PF16278.5 EAY02174.1 - 0.022 15.2 2.0 1.9 9.0 0.2 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PKHD_C PF18331.1 EAY02174.1 - 0.16 12.0 1.1 9.5 6.4 0.3 2.5 1 1 1 2 2 2 0 PKHD-type hydroxylase C-terminal domain Occludin_ELL PF07303.13 EAY02174.1 - 0.19 12.5 2.7 2.9 8.6 0.3 2.3 2 0 0 2 2 2 0 Occludin homology domain KIAA1430 PF13879.6 EAY02175.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HTH_32 PF13565.6 EAY02176.1 - 1.1 9.9 3.7 2.8 8.6 3.7 1.6 1 1 0 1 1 1 0 Homeodomain-like domain YvrJ PF12841.7 EAY02177.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Tmemb_9 PF05434.11 EAY02178.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 AbiJ_NTD4 PF18863.1 EAY02179.1 - 0.032 14.7 0.4 0.073 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 VirK PF06903.12 EAY02179.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 VirK protein Ribosomal_L7Ae PF01248.26 EAY02181.1 - 1.8e-17 62.9 0.0 2.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1374 PF07118.11 EAY02182.1 - 0.018 15.5 0.5 0.033 14.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) DUF1651 PF07864.11 EAY02182.1 - 0.085 13.2 0.1 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) PilW PF16074.5 EAY02182.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Orf78 PF06024.12 EAY02183.1 - 0.0065 16.7 0.7 0.011 16.0 0.7 1.3 1 0 0 1 1 1 1 Orf78 (ac78) TRIQK PF15168.6 EAY02183.1 - 0.0074 16.2 0.9 0.013 15.4 0.9 1.3 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family PIG-Y PF15159.6 EAY02183.1 - 0.061 14.3 0.1 0.13 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Ndufs5 PF10200.9 EAY02183.1 - 0.17 12.1 0.2 0.41 10.9 0.2 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3781 PF12636.7 EAY02184.1 - 0.026 14.4 0.8 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4107 PF13389.6 EAY02185.1 - 1.5e-71 239.8 3.8 2.1e-71 239.3 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF1476 PF07345.11 EAY02185.1 - 0.027 14.8 0.6 0.048 14.0 0.1 1.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Amidase02_C PF12123.8 EAY02186.1 - 0.0071 16.0 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase DUF3839 PF12943.7 EAY02187.1 - 9.9e-100 333.0 8.4 1.1e-99 332.8 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) PTR PF12789.7 EAY02189.1 - 0.03 14.4 0.1 0.03 14.4 0.1 4.3 5 0 0 5 5 5 0 Phage tail repeat like UCH PF00443.29 EAY02192.1 - 1.2e-30 106.9 9.6 1.2e-30 106.9 9.6 3.1 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAY02192.1 - 3.1e-06 27.0 17.2 0.00078 19.1 0.4 3.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Helicase_C PF00271.31 EAY02192.1 - 0.038 14.3 0.9 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain FRB_dom PF08771.11 EAY02192.1 - 0.12 12.9 1.0 1.7 9.1 0.1 3.3 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain DUF1765 PF08578.10 EAY02192.1 - 6.6 7.2 8.6 1.5 9.3 0.1 3.9 3 1 2 5 5 5 0 Protein of unknown function (DUF1765) IF4E PF01652.18 EAY02194.1 - 5.7e-46 156.2 0.0 6.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KIAA1430 PF13879.6 EAY02195.1 - 0.015 16.0 2.5 0.024 15.4 2.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue CompInhib_SCIN PF11546.8 EAY02196.1 - 0.075 13.1 0.3 0.078 13.0 0.3 1.0 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF4107 PF13389.6 EAY02197.1 - 0.088 13.0 0.2 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A32 PF04665.12 EAY02198.1 - 1.6e-08 34.3 1.0 3.5e-08 33.2 0.1 2.0 2 1 0 2 2 2 1 Poxvirus A32 protein Zot PF05707.12 EAY02198.1 - 1.6e-07 31.2 0.2 8.6e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) SPATA24 PF15175.6 EAY02198.1 - 0.065 13.1 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 VirK PF06903.12 EAY02199.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 VirK protein DUF641 PF04859.12 EAY02200.1 - 0.031 14.6 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 EAY02200.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor ISG65-75 PF11727.8 EAY02201.1 - 0.089 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein PseudoU_synth_2 PF00849.22 EAY02204.1 - 1e-25 90.7 0.1 1.9e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EAY02204.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 S4 domain Metallophos PF00149.28 EAY02205.1 - 8.3e-31 108.1 0.3 1.2e-30 107.5 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BH4 PF02180.17 EAY02205.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Serpin PF00079.20 EAY02206.1 - 0.0093 15.3 0.8 0.021 14.1 0.8 1.7 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Glug PF07581.12 EAY02206.1 - 0.11 12.9 12.2 0.16 12.5 0.0 4.6 4 1 0 4 4 4 0 The GLUG motif DUF1374 PF07118.11 EAY02206.1 - 0.65 10.5 4.6 2.4 8.7 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1374) Pentapeptide_3 PF13576.6 EAY02206.1 - 1.5 9.1 16.5 6.2 7.1 0.5 4.3 3 2 1 4 4 4 0 Pentapeptide repeats (9 copies) Filament PF00038.21 EAY02208.1 - 3.3e-05 23.6 48.0 3.3e-05 23.6 48.0 4.3 3 2 2 5 5 5 2 Intermediate filament protein Med9 PF07544.13 EAY02208.1 - 0.00014 21.9 5.3 0.00014 21.9 5.3 10.7 3 2 7 10 10 10 3 RNA polymerase II transcription mediator complex subunit 9 Lipase_GDSL PF00657.22 EAY02208.1 - 0.022 14.7 0.8 0.022 14.7 0.8 5.7 2 2 2 4 4 4 0 GDSL-like Lipase/Acylhydrolase Ank_2 PF12796.7 EAY02209.1 - 1.5e-99 326.7 38.3 1.9e-19 70.0 1.1 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY02209.1 - 3.3e-91 298.1 31.6 1e-12 48.0 0.3 7.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAY02209.1 - 6.9e-91 295.1 22.5 4e-09 36.5 0.1 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 EAY02209.1 - 8.7e-87 284.5 28.0 4.6e-12 46.2 0.1 10.2 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02209.1 - 5.3e-71 226.1 15.5 1.8e-06 27.8 0.0 10.2 10 0 0 10 10 10 10 Ankyrin repeat ThiS-like PF14453.6 EAY02209.1 - 6.1e-13 48.6 12.9 6.3 6.9 0.0 9.2 1 1 8 9 9 9 3 ThiS-like ubiquitin CCG PF02754.16 EAY02209.1 - 8.5e-13 48.3 4.0 0.32 11.2 0.0 5.7 1 1 6 7 7 7 7 Cysteine-rich domain MetallophosN PF16371.5 EAY02209.1 - 7e-12 45.5 0.1 0.17 12.1 0.0 5.9 1 1 8 9 9 9 7 N terminal of Calcineurin-like phosphoesterase PH_8 PF15409.6 EAY02209.1 - 2.6e-07 30.8 1.3 40 4.6 0.0 7.9 1 1 8 9 9 9 0 Pleckstrin homology domain CEP44 PF15007.6 EAY02209.1 - 4.9e-05 23.5 0.1 50 4.1 0.0 6.6 1 1 7 9 9 9 0 Centrosomal spindle body, CEP44 CCDC84 PF14968.6 EAY02209.1 - 0.00091 19.0 0.1 6.9 6.2 0.0 5.6 1 1 3 4 4 4 1 Coiled coil protein 84 DUF1373 PF07117.11 EAY02209.1 - 0.015 15.3 0.3 20 5.1 0.0 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1373) Toxin_38 PF14866.6 EAY02209.1 - 0.02 15.2 0.0 81 3.6 0.0 3.5 3 0 0 3 3 3 0 Potassium channel toxin DUF3447 PF11929.8 EAY02209.1 - 0.04 13.9 3.4 0.055 13.4 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Toxin_35 PF10530.9 EAY02209.1 - 0.045 13.7 19.0 14 5.7 0.0 7.9 9 0 0 9 9 9 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold DUF3863 PF12979.7 EAY02209.1 - 0.74 8.6 2.4 56 2.4 0.0 3.4 2 1 3 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3863) Adaptin_N PF01602.20 EAY02210.1 - 6.1e-18 64.7 0.7 9.4e-18 64.1 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region SAM_4 PF18017.1 EAY02210.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ras PF00071.22 EAY02211.1 - 2.5e-38 131.2 0.1 3e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY02211.1 - 1.3e-26 93.2 0.0 2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY02211.1 - 1e-12 47.9 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY02211.1 - 0.00013 21.4 0.2 0.00023 20.6 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAY02211.1 - 0.0005 20.0 0.2 0.054 13.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAY02211.1 - 0.016 14.7 0.0 0.044 13.3 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EAY02211.1 - 0.028 14.2 0.6 0.17 11.6 0.6 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EAY02211.1 - 0.07 13.2 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAY02211.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EAY02211.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Sulfatase PF00884.23 EAY02212.1 - 1e-10 41.5 0.2 7.4e-10 38.7 0.2 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EAY02212.1 - 0.0027 17.3 1.1 0.74 9.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase LigB PF02900.18 EAY02212.1 - 0.004 16.3 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Metalloenzyme PF01676.18 EAY02212.1 - 0.053 12.9 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF334 PF03904.13 EAY02212.1 - 0.066 12.7 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Guanylate_cyc PF00211.20 EAY02213.1 - 5.7e-38 130.4 0.0 1.3e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EAY02213.1 - 1.3e-15 57.5 2.0 1.4e-14 54.2 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EAY02213.1 - 6.3e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EAY02213.1 - 2.2e-06 27.9 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EAY02213.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 EAY02213.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold EphA2_TM PF14575.6 EAY02213.1 - 0.39 11.6 7.4 3.3 8.6 0.1 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CDT1 PF08839.11 EAY02214.1 - 0.018 15.4 1.1 0.036 14.4 0.1 2.0 2 0 0 2 2 2 0 DNA replication factor CDT1 like Popeye PF04831.13 EAY02214.1 - 7.7 6.7 8.3 4 7.6 4.4 2.4 1 1 0 1 1 1 0 Popeye protein conserved region EI24 PF07264.11 EAY02214.1 - 8.6 6.6 12.6 5.4 7.2 0.0 3.5 4 0 0 4 4 4 0 Etoposide-induced protein 2.4 (EI24) Pkinase_Tyr PF07714.17 EAY02215.1 - 2.8e-28 98.9 0.0 5.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAY02215.1 - 1.2e-23 83.8 0.0 2.2e-23 83.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EAY02215.1 - 0.0016 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAY02215.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAY02215.1 - 0.057 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Homeobox_KN PF05920.11 EAY02216.1 - 4.4e-11 42.5 0.2 8.9e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAY02216.1 - 3.1e-08 33.3 0.2 5.2e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Myb_DNA-binding PF00249.31 EAY02217.1 - 3.9e-28 97.4 1.0 3.6e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAY02217.1 - 1.5e-25 89.2 2.0 1.9e-12 47.2 0.5 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAY02217.1 - 0.00032 20.7 0.5 1.1 9.4 0.2 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAY02217.1 - 0.0022 18.2 0.2 0.0043 17.2 0.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EAY02217.1 - 0.037 14.2 1.2 1.5 9.0 0.1 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EAY02217.1 - 0.24 11.3 4.4 1 9.3 0.9 2.5 1 1 2 3 3 3 0 Myb DNA-binding like CDC50 PF03381.15 EAY02218.1 - 7.2e-60 202.9 3.8 9.5e-60 202.5 3.8 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.6 EAY02218.1 - 0.075 13.8 3.2 0.079 13.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) RICTOR_M PF14666.6 EAY02219.1 - 0.024 14.4 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EAY02219.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 SRR1 PF07985.12 EAY02219.1 - 0.054 13.5 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 SRR1 Enkurin PF13864.6 EAY02220.1 - 2e-22 79.4 1.4 5.6e-22 78.0 1.4 1.8 1 0 0 1 1 1 1 Calmodulin-binding TPR_1 PF00515.28 EAY02221.1 - 9.2e-05 22.1 0.1 0.008 16.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAY02221.1 - 0.00011 22.4 0.1 0.0014 18.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ribosomal_L29e PF01779.17 EAY02222.1 - 6.2e-14 52.0 7.4 8e-14 51.7 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Kelch_4 PF13418.6 EAY02224.1 - 1.7e-15 56.8 6.1 0.001 19.0 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAY02224.1 - 4.2e-15 55.4 12.8 1.3e-05 25.3 0.1 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EAY02224.1 - 2.7e-10 40.2 11.4 0.0017 18.6 0.6 6.0 5 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EAY02224.1 - 3e-09 36.5 12.2 6.8e-05 22.7 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EAY02224.1 - 8.6e-09 35.2 10.7 0.0088 16.0 0.7 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EAY02224.1 - 1.1e-08 34.5 13.0 0.013 15.1 1.2 4.9 5 0 0 5 5 5 3 Kelch motif PSP PF04046.16 EAY02225.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TMP PF05017.14 EAY02226.1 - 0.079 13.6 5.7 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat DUF1493 PF07377.12 EAY02227.1 - 0.02 15.3 0.5 0.046 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAY02227.1 - 0.69 10.0 3.7 8.5 6.5 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein IBD PF10416.9 EAY02228.1 - 1.8e-25 89.4 0.0 2.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DnaJ PF00226.31 EAY02229.1 - 1.8e-14 53.6 2.4 1.8e-14 53.6 2.4 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 EAY02229.1 - 2.6e-12 45.8 12.5 0.0011 18.9 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAY02229.1 - 2.8e-10 40.5 6.8 0.00016 22.2 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAY02229.1 - 1.6e-09 37.1 20.1 0.00033 20.3 0.0 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAY02229.1 - 7.8e-09 35.1 8.6 0.019 15.1 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAY02229.1 - 1.5e-07 31.5 11.5 0.00072 19.7 0.2 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EAY02229.1 - 7.6e-07 29.2 0.0 0.015 15.5 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAY02229.1 - 3.9e-06 27.4 0.4 0.35 11.6 0.1 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAY02229.1 - 7.1e-06 26.2 4.3 5.5 7.3 0.1 5.9 4 2 1 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAY02229.1 - 7.4e-06 26.0 8.4 0.05 13.6 0.8 3.7 3 1 0 3 3 3 3 Putative TPR-like repeat TPR_11 PF13414.6 EAY02229.1 - 5.3e-05 22.8 5.9 0.2 11.4 0.5 5.4 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.6 EAY02229.1 - 0.00013 22.4 2.9 3.4 8.5 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAY02229.1 - 0.012 15.9 3.9 5.6 7.6 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAY02229.1 - 0.016 16.0 0.5 41 5.4 0.1 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EAY02229.1 - 0.025 14.0 0.0 4 6.7 0.0 3.1 3 0 0 3 3 3 0 MalT-like TPR region SHNi-TPR PF10516.9 EAY02229.1 - 0.058 12.9 1.3 0.81 9.2 0.1 3.2 4 0 0 4 4 4 0 SHNi-TPR TPR_21 PF09976.9 EAY02229.1 - 0.96 9.1 6.3 0.49 10.1 0.2 3.1 2 2 0 2 2 2 0 Tetratricopeptide repeat-like domain CD34_antigen PF06365.12 EAY02230.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4268 PF14088.6 EAY02230.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) LapA_dom PF06305.11 EAY02230.1 - 0.12 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 EAY02230.1 - 0.12 13.3 0.4 0.47 11.4 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RasGAP PF00616.19 EAY02231.1 - 0.00028 20.7 0.3 0.00028 20.7 0.3 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF2227 PF09988.9 EAY02231.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Chlam_PMP PF02415.17 EAY02232.1 - 2.6e-05 24.4 11.0 0.17 12.4 1.3 3.5 3 0 0 3 3 3 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Syndecan PF01034.20 EAY02233.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 EAY02233.1 - 0.012 16.5 0.0 0.038 14.9 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EAY02233.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Orf78 PF06024.12 EAY02233.1 - 0.022 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF4969 PF16339.5 EAY02233.1 - 0.14 12.6 0.3 0.29 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) DUF4795 PF16043.5 EAY02234.1 - 3.5e-06 26.8 17.1 0.086 12.4 0.9 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4795) Glyco_transf_49 PF13896.6 EAY02234.1 - 0.0054 16.1 0.3 0.0098 15.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF2344 PF10105.9 EAY02234.1 - 0.49 10.2 2.5 18 5.1 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) Phage_fiber PF03335.13 EAY02234.1 - 8.4 6.9 9.7 0.95 9.8 1.9 2.4 2 0 0 2 2 2 0 Phage tail fibre repeat Pox_A32 PF04665.12 EAY02236.1 - 5e-05 22.9 2.7 8.1e-05 22.2 2.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY02236.1 - 0.0047 16.9 0.7 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAY02236.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Gly-zipper_Omp PF13488.6 EAY02237.1 - 0.0071 16.3 9.0 0.01 15.8 9.0 1.2 1 0 0 1 1 1 1 Glycine zipper ActA PF05058.12 EAY02237.1 - 0.25 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 ActA Protein DUF1269 PF06897.12 EAY02237.1 - 0.29 11.4 4.8 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY02237.1 - 1.3 9.1 5.7 2.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4108 PF13390.6 EAY02238.1 - 1.3e-76 255.4 13.8 1.5e-76 255.2 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) PdaC PF13739.6 EAY02238.1 - 0.9 10.6 4.3 2.1 9.4 4.3 1.6 1 0 0 1 1 1 0 Deacetylase PdaC Syndecan PF01034.20 EAY02240.1 - 0.00082 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain TMEM51 PF15345.6 EAY02240.1 - 0.029 14.2 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2207 PF09972.9 EAY02240.1 - 0.041 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 EAY02240.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Ac76 PF05814.11 EAY02240.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) Chlam_PMP PF02415.17 EAY02241.1 - 0.00023 21.4 11.0 0.19 12.3 1.3 3.5 3 0 0 3 3 3 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Nbl1_Borealin_N PF10444.9 EAY02242.1 - 0.084 12.5 4.5 0.55 9.9 0.5 3.6 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal DUF3439 PF11921.8 EAY02244.1 - 0.039 13.9 1.1 0.093 12.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Inos-1-P_synth PF01658.17 EAY02244.1 - 0.081 13.2 0.7 1.5 9.1 0.5 2.4 2 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase NOA36 PF06524.12 EAY02244.1 - 6 6.1 20.1 10 5.4 20.1 1.3 1 0 0 1 1 1 0 NOA36 protein Thioredoxin PF00085.20 EAY02245.1 - 4.3e-08 33.1 0.0 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EAY02245.1 - 0.004 17.6 0.6 0.56 10.7 0.1 3.1 1 1 0 2 2 2 1 Thioredoxin-like domain DUF3974 PF13120.6 EAY02245.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Skp1 PF01466.19 EAY02245.1 - 0.13 12.4 0.5 0.29 11.3 0.5 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Ribosomal_L13e PF01294.18 EAY02246.1 - 6.8e-55 185.7 8.6 9.1e-55 185.3 8.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ank_4 PF13637.6 EAY02247.1 - 1.2e-68 226.6 26.0 8.5e-12 45.4 0.1 7.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EAY02247.1 - 2.5e-60 198.4 13.8 4.8e-07 29.9 0.1 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_2 PF12796.7 EAY02247.1 - 1.8e-59 198.3 35.4 8.8e-23 80.7 5.0 5.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02247.1 - 5.7e-52 167.6 14.8 2.2e-05 24.5 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAY02247.1 - 4.8e-45 151.0 30.8 2.4e-10 40.4 0.1 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EAY02247.1 - 0.0093 15.7 10.1 6.2 6.4 0.1 5.2 1 1 4 6 6 6 2 Shigella flexneri OspC protein DUF4147 PF13660.6 EAY02247.1 - 0.011 15.4 6.5 2.2 7.8 0.0 5.8 5 2 2 7 7 7 0 Domain of unknown function (DUF4147) RNase_PH_C PF03725.15 EAY02247.1 - 0.031 14.3 4.0 30 4.7 0.1 5.3 3 2 3 6 6 6 0 3' exoribonuclease family, domain 2 DUF249 PF03158.13 EAY02247.1 - 0.032 14.0 11.0 3 7.5 1.5 4.1 3 1 1 4 4 4 0 Multigene family 530 protein RNA_pol_Rpb1_3 PF04983.18 EAY02247.1 - 0.06 13.3 1.4 4.8 7.1 1.4 2.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 PUF PF00806.19 EAY02249.1 - 0.011 15.4 0.1 4.3 7.2 0.0 3.6 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat D123 PF07065.14 EAY02249.1 - 0.24 10.5 6.0 0.7 9.0 6.0 1.8 1 0 0 1 1 1 0 D123 RRN3 PF05327.11 EAY02249.1 - 0.95 7.9 5.2 18 3.7 4.1 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 EAY02249.1 - 5.3 5.7 6.1 9.5 4.9 6.1 1.3 1 0 0 1 1 1 0 Presenilin YrhK PF14145.6 EAY02250.1 - 0.043 13.7 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 YrhK-like protein ETRAMP PF09716.10 EAY02250.1 - 0.059 13.4 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4108 PF13390.6 EAY02251.1 - 3.3e-62 208.6 8.4 3.7e-62 208.5 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Mating_C PF12737.7 EAY02252.1 - 0.72 9.0 4.3 0.93 8.6 4.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 ResIII PF04851.15 EAY02253.1 - 0.00012 22.2 2.3 0.00021 21.4 2.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAY02253.1 - 0.00019 21.7 0.0 0.00064 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAY02253.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EAY02253.1 - 0.0012 18.7 0.9 0.0037 17.1 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAY02253.1 - 0.0054 17.1 0.0 0.0074 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAY02253.1 - 0.02 14.6 0.2 0.38 10.4 0.0 2.2 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAY02253.1 - 0.033 13.6 0.1 0.05 13.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein DUF4588 PF15251.6 EAY02253.1 - 0.076 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) AAA_25 PF13481.6 EAY02253.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1827 PF08860.10 EAY02253.1 - 0.17 12.1 4.3 4.9 7.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3839 PF12943.7 EAY02254.1 - 9.5e-154 509.8 14.9 1.2e-153 509.5 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY02254.1 - 0.041 13.7 0.7 0.082 12.8 0.5 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase Rx_N PF18052.1 EAY02254.1 - 0.056 13.7 1.3 4.3 7.7 0.0 3.6 3 1 1 4 4 4 0 Rx N-terminal domain Cor1 PF04803.12 EAY02254.1 - 0.17 12.1 3.8 0.21 11.8 0.2 2.7 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region KELK PF15796.5 EAY02254.1 - 0.87 10.1 6.8 1.6 9.2 0.7 3.1 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAY02255.1 - 0.042 14.3 0.5 0.094 13.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SL4P PF17618.2 EAY02255.1 - 0.78 9.8 3.8 9.8 6.3 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein TMP PF05017.14 EAY02256.1 - 0.03 14.8 3.3 11 7.2 0.2 3.1 3 0 0 3 3 3 0 TMP repeat Kinesin PF00225.23 EAY02258.1 - 3.8e-80 269.3 0.4 6e-80 268.7 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAY02258.1 - 2.3e-24 86.0 0.0 7.2e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding SLATT_5 PF18160.1 EAY02258.1 - 1.7 7.9 5.0 2 7.7 3.7 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Tfb4 PF03850.14 EAY02259.1 - 7.4e-34 117.5 0.0 9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C3HC4_3 PF13920.6 EAY02259.1 - 0.033 14.1 2.7 0.065 13.1 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAY02259.1 - 0.064 13.1 1.7 0.16 11.9 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 EAY02259.1 - 0.16 12.3 2.8 3.4 8.1 0.2 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding UPF0547 PF10571.9 EAY02259.1 - 0.71 10.0 4.3 1.3 9.2 4.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn-C2H2_12 PF18112.1 EAY02259.1 - 0.73 10.3 4.2 1.9 9.0 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Pkinase PF00069.25 EAY02261.1 - 8.3e-82 274.5 0.0 9.8e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02261.1 - 3.7e-50 170.6 0.0 4.6e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY02261.1 - 1.4e-13 50.9 0.0 7e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EAY02261.1 - 0.00025 20.7 0.2 0.0019 17.8 0.0 2.0 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.14 EAY02261.1 - 0.00082 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAY02261.1 - 0.0043 15.9 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAY02261.1 - 0.011 14.8 0.3 0.1 11.6 0.1 2.0 1 1 1 2 2 2 0 Seadornavirus VP7 PI3Ka PF00613.20 EAY02261.1 - 0.015 14.7 0.1 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TTRAP PF14203.6 EAY02261.1 - 0.022 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein FTA2 PF13095.6 EAY02261.1 - 0.047 13.3 0.2 0.21 11.2 0.1 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAY02261.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DNA_pol_E_B PF04042.16 EAY02262.1 - 1.6e-33 115.8 1.5 2.8e-33 115.1 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ANAPC4_WD40 PF12894.7 EAY02264.1 - 4.5e-05 23.7 0.1 1.1 9.6 0.0 3.9 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAY02264.1 - 0.00057 19.3 5.3 0.016 14.6 0.6 2.3 1 1 0 1 1 1 1 WD40-like domain NUP214 PF16755.5 EAY02264.1 - 0.0037 16.6 0.6 0.91 8.7 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 DUF1899 PF08953.11 EAY02264.1 - 0.0055 16.6 0.2 0.82 9.6 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1899) zf-dskA_traR PF01258.17 EAY02264.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger PQQ_3 PF13570.6 EAY02264.1 - 0.04 14.4 0.1 18 6.0 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain HSP90 PF00183.18 EAY02265.1 - 1.8e-135 452.8 10.6 2.7e-135 452.2 10.6 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EAY02265.1 - 1.5e-11 44.3 0.2 3.7e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAY02265.1 - 1e-10 42.1 0.4 1.8e-10 41.3 0.4 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpmSyn_N PF17950.1 EAY02266.1 - 0.4 10.9 1.9 23 5.3 0.2 3.4 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal PUF PF00806.19 EAY02266.1 - 2.7 7.9 4.5 1.1 9.1 0.2 2.8 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Peptidase_M8 PF01457.16 EAY02267.1 - 2.8e-12 46.1 0.1 6.9e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 Leishmanolysin TMEM154 PF15102.6 EAY02267.1 - 3.8e-06 26.8 4.5 6.4e-06 26.1 4.5 1.3 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 EAY02267.1 - 0.00038 19.9 0.2 0.00061 19.3 0.2 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5305 PF17231.2 EAY02267.1 - 0.00056 19.4 0.4 0.001 18.5 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Orf78 PF06024.12 EAY02267.1 - 0.0032 17.7 0.9 0.0069 16.7 0.9 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Peptidase_M56 PF05569.11 EAY02267.1 - 0.0053 16.0 0.0 0.0088 15.3 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4448 PF14610.6 EAY02267.1 - 0.0075 16.1 0.2 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF3377 PF11857.8 EAY02267.1 - 0.0097 15.8 0.2 0.02 14.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 EAY02267.1 - 0.012 16.5 0.1 0.027 15.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIC3 PF15361.6 EAY02267.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Protocadherin PF08374.11 EAY02267.1 - 0.033 14.1 0.3 0.056 13.4 0.3 1.2 1 0 0 1 1 1 0 Protocadherin Peptidase_M64 PF09471.10 EAY02267.1 - 0.045 13.3 0.5 0.089 12.3 0.5 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Insulin_TMD PF17870.1 EAY02267.1 - 0.058 13.5 4.9 0.15 12.1 4.9 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRRC37AB_C PF14914.6 EAY02267.1 - 0.067 13.1 0.6 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain UL45 PF05473.12 EAY02267.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like ABC2_membrane_3 PF12698.7 EAY02267.1 - 0.22 10.6 0.9 0.28 10.2 0.2 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4519 PF15012.6 EAY02267.1 - 5.4 7.3 5.6 6.9 6.9 4.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) TMEM154 PF15102.6 EAY02268.1 - 0.014 15.3 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DAP10 PF07213.11 EAY02268.1 - 0.021 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein DUF5305 PF17231.2 EAY02268.1 - 0.028 13.8 0.3 0.041 13.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 EAY02268.1 - 0.045 14.6 0.2 0.1 13.5 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 EAY02268.1 - 0.086 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Gly_rich PF12810.7 EAY02269.1 - 5.4e-15 56.0 8.6 6.2e-15 55.8 8.6 1.0 1 0 0 1 1 1 1 Glycine rich protein DUF3152 PF11350.8 EAY02270.1 - 0.036 13.7 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Peptidase_M8 PF01457.16 EAY02272.1 - 8.4e-05 21.4 0.0 0.068 11.9 0.0 2.2 2 0 0 2 2 2 2 Leishmanolysin ODV-E18 PF10717.9 EAY02272.1 - 0.00031 20.6 0.2 0.0026 17.6 0.0 2.5 3 0 0 3 3 3 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 EAY02272.1 - 0.055 14.3 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAY02272.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 EAY02272.1 - 0.15 12.4 0.3 0.31 11.3 0.3 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_M8 PF01457.16 EAY02273.1 - 1.7e-10 40.2 0.1 2e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Leishmanolysin TMEM154 PF15102.6 EAY02273.1 - 3.9e-05 23.6 2.1 8.7e-05 22.4 2.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.8 EAY02273.1 - 0.0036 17.2 0.1 0.0092 15.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 EAY02273.1 - 0.0042 17.9 0.0 0.0092 16.8 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAY02273.1 - 0.005 16.9 7.7 0.012 15.7 7.7 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Protocadherin PF08374.11 EAY02273.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Protocadherin DUF5385 PF17359.2 EAY02273.1 - 0.018 14.6 0.9 0.034 13.7 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Zip PF02535.22 EAY02273.1 - 0.021 14.0 0.2 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_M10 PF00413.24 EAY02273.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF3139 PF11337.8 EAY02273.1 - 0.036 14.7 2.4 0.12 13.0 2.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Shisa PF13908.6 EAY02273.1 - 0.05 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 EAY02273.1 - 0.061 12.9 0.8 0.19 11.3 0.8 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3169 PF11368.8 EAY02273.1 - 0.12 11.9 1.1 0.2 11.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PAP2_C PF14360.6 EAY02273.1 - 0.63 10.6 4.0 0.99 10.0 0.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF4519 PF15012.6 EAY02273.1 - 1.5 9.0 6.2 3.4 7.9 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ODV-E18 PF10717.9 EAY02274.1 - 0.0054 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 TssO PF17561.2 EAY02274.1 - 0.017 15.2 0.6 0.028 14.5 0.6 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Tetraspanin PF00335.20 EAY02274.1 - 0.035 13.8 0.1 0.052 13.2 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family EphA2_TM PF14575.6 EAY02274.1 - 0.043 14.7 0.0 0.08 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5083 PF16890.5 EAY02274.1 - 0.045 13.5 0.3 0.07 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) OAD_gamma PF04277.13 EAY02274.1 - 0.052 14.1 0.0 0.091 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PspB PF06667.12 EAY02274.1 - 0.083 12.9 0.9 0.18 11.9 0.9 1.6 1 1 0 1 1 1 0 Phage shock protein B E1-E2_ATPase PF00122.20 EAY02274.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Orf78 PF06024.12 EAY02274.1 - 9.4 6.6 7.0 2 8.8 3.1 1.8 1 1 1 2 2 2 0 Orf78 (ac78) Peptidase_M8 PF01457.16 EAY02275.1 - 6e-07 28.5 0.0 0.00033 19.5 0.0 2.1 2 0 0 2 2 2 2 Leishmanolysin AAA_31 PF13614.6 EAY02275.1 - 0.068 13.1 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 AAA domain TMEM154 PF15102.6 EAY02276.1 - 3.2e-05 23.9 3.5 3.2e-05 23.9 3.5 1.4 2 0 0 2 2 1 1 TMEM154 protein family Peptidase_M8 PF01457.16 EAY02276.1 - 8e-05 21.5 0.0 0.00019 20.3 0.0 1.5 2 0 0 2 2 2 1 Leishmanolysin Orf78 PF06024.12 EAY02276.1 - 0.00068 19.9 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 EAY02276.1 - 0.0017 17.8 0.2 0.0032 16.9 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Mid2 PF04478.12 EAY02276.1 - 0.0021 17.9 1.9 0.0043 16.9 1.9 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DAG1 PF05454.11 EAY02276.1 - 0.0027 17.2 0.3 0.0036 16.7 0.3 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) LRRC37AB_C PF14914.6 EAY02276.1 - 0.0058 16.6 0.1 0.0089 15.9 0.1 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain CrgA PF06781.12 EAY02276.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA Protocadherin PF08374.11 EAY02276.1 - 0.017 15.1 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Protocadherin DUF4448 PF14610.6 EAY02276.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5385 PF17359.2 EAY02276.1 - 0.022 14.3 1.4 0.038 13.5 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF3377 PF11857.8 EAY02276.1 - 0.029 14.3 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Baculo_11_kDa PF06143.11 EAY02276.1 - 0.033 13.8 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.6 EAY02276.1 - 0.034 14.4 0.5 0.034 14.4 0.5 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 EAY02276.1 - 0.037 12.8 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ODV-E18 PF10717.9 EAY02276.1 - 0.087 12.7 1.1 0.31 11.0 1.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.12 EAY02276.1 - 0.1 12.2 0.2 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 EAY02276.1 - 0.13 13.2 0.4 0.27 12.1 0.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5383 PF17355.2 EAY02276.1 - 0.14 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Collectrin PF16959.5 EAY02276.1 - 0.14 11.9 2.6 0.24 11.2 2.6 1.3 1 0 0 1 1 1 0 Renal amino acid transporter ASFV_J13L PF05568.11 EAY02276.1 - 0.2 11.4 0.8 0.32 10.7 0.8 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Insulin_TMD PF17870.1 EAY02276.1 - 0.22 11.6 7.4 0.55 10.3 7.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 EAY02278.1 - 1e-07 32.0 0.7 1.2e-07 31.7 0.7 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 EAY02278.1 - 0.00015 21.3 0.2 0.00018 21.0 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Mid2 PF04478.12 EAY02278.1 - 0.00027 20.8 0.2 0.00032 20.6 0.2 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Orf78 PF06024.12 EAY02278.1 - 0.00067 19.9 1.5 0.00085 19.6 0.7 1.5 1 1 1 2 2 2 1 Orf78 (ac78) Insulin_TMD PF17870.1 EAY02278.1 - 0.001 19.0 3.7 0.0015 18.6 3.7 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment LRRC37AB_C PF14914.6 EAY02278.1 - 0.0014 18.6 1.1 0.0018 18.2 1.1 1.2 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Shisa PF13908.6 EAY02278.1 - 0.0018 18.6 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF5385 PF17359.2 EAY02278.1 - 0.0026 17.3 1.3 0.0029 17.2 0.4 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5385) CrgA PF06781.12 EAY02278.1 - 0.0032 17.5 0.1 0.0063 16.5 0.0 1.5 1 1 1 2 2 2 1 Cell division protein CrgA Protocadherin PF08374.11 EAY02278.1 - 0.0035 17.3 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 EAY02278.1 - 0.0037 18.1 0.4 0.008 17.0 0.1 1.7 1 1 1 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 EAY02278.1 - 0.004 17.0 0.1 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.6 EAY02278.1 - 0.0042 16.9 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 EAY02278.1 - 0.0053 16.4 0.0 0.006 16.2 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2207 PF09972.9 EAY02278.1 - 0.0056 15.5 0.0 0.0062 15.4 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 EAY02278.1 - 0.0058 16.5 0.0 0.0069 16.3 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 BatD PF13584.6 EAY02278.1 - 0.0088 14.9 0.0 0.01 14.7 0.0 1.0 1 0 0 1 1 1 1 Oxygen tolerance ODV-E18 PF10717.9 EAY02278.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 AMA-1 PF02430.15 EAY02278.1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF4711 PF15829.5 EAY02278.1 - 0.018 15.0 0.9 0.024 14.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DAG1 PF05454.11 EAY02278.1 - 0.019 14.3 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Collectrin PF16959.5 EAY02278.1 - 0.034 13.9 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter TMEM223 PF14640.6 EAY02278.1 - 0.046 13.9 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 223 PRIMA1 PF16101.5 EAY02278.1 - 0.046 13.7 1.6 0.077 13.0 1.6 1.3 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Herpes_gE PF02480.16 EAY02278.1 - 0.047 12.4 0.0 0.047 12.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4519 PF15012.6 EAY02278.1 - 0.047 13.9 0.4 0.092 12.9 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4519) DUF5383 PF17355.2 EAY02278.1 - 0.047 14.1 1.0 0.066 13.6 0.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5383) SID-1_RNA_chan PF13965.6 EAY02278.1 - 0.055 11.9 0.0 0.06 11.7 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRP PF06011.12 EAY02278.1 - 0.058 12.1 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel UL45 PF05473.12 EAY02278.1 - 0.062 12.9 0.3 0.087 12.5 0.3 1.3 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PIRT PF15099.6 EAY02278.1 - 0.063 12.9 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Amnionless PF14828.6 EAY02278.1 - 0.066 12.0 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless E7 PF00527.18 EAY02278.1 - 0.091 13.0 0.3 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 E7 protein, Early protein Peptidase_M56 PF05569.11 EAY02278.1 - 0.091 11.9 0.0 0.095 11.9 0.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 SARAF PF06682.12 EAY02278.1 - 0.098 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RIC3 PF15361.6 EAY02278.1 - 0.15 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Conotoxin PF02950.17 EAY02278.1 - 0.16 13.0 0.3 2.4 9.2 0.0 2.0 1 1 1 2 2 2 0 Conotoxin DUF3899 PF13038.6 EAY02278.1 - 0.21 12.1 2.3 0.25 11.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) DUF4834 PF16118.5 EAY02278.1 - 0.36 11.8 0.1 0.36 11.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 EAY02278.1 - 0.91 9.1 3.9 1.2 8.7 3.8 1.4 1 1 0 1 1 1 0 Baculovirus 11 kDa family Peptidase_M8 PF01457.16 EAY02279.1 - 1e-10 41.0 0.0 5.5e-09 35.3 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin Peptidase_M90 PF06167.12 EAY02279.1 - 0.007 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 PTR PF12789.7 EAY02280.1 - 1.2e-49 166.1 31.4 6.4e-32 109.4 15.7 4.3 2 2 1 3 3 3 2 Phage tail repeat like DUF4116 PF13475.6 EAY02280.1 - 0.028 14.1 1.0 0.055 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) TMP PF05017.14 EAY02283.1 - 0.051 14.1 4.8 11 7.2 0.2 3.3 3 0 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY02284.1 - 0.11 12.4 1.3 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 PSP Mitoc_L55 PF09776.9 EAY02285.1 - 2.3 8.0 7.3 9.6 6.0 0.9 3.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L55 DUF1681 PF07933.14 EAY02287.1 - 1e-47 161.5 0.0 1.2e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IBN_N PF03810.19 EAY02288.1 - 2.6e-07 30.5 6.9 5e-07 29.5 0.4 4.7 6 0 0 6 6 6 1 Importin-beta N-terminal domain DRIM PF07539.12 EAY02288.1 - 3.6e-06 25.6 3.7 0.0012 17.2 0.1 2.8 2 1 1 3 3 3 2 Down-regulated in metastasis AbiH PF14253.6 EAY02288.1 - 0.0056 16.6 3.0 16 5.2 0.2 3.9 3 1 0 4 4 4 1 Bacteriophage abortive infection AbiH PRANC PF09372.10 EAY02288.1 - 0.0083 16.4 3.8 0.026 14.8 0.3 3.4 3 1 1 4 4 4 1 PRANC domain HEAT_EZ PF13513.6 EAY02288.1 - 0.011 16.2 0.0 1.3 9.6 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat CP_ATPgrasp_1 PF04174.13 EAY02288.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Stork_head PF10264.9 EAY02288.1 - 0.074 13.2 0.1 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Cnd1 PF12717.7 EAY02288.1 - 0.14 12.1 11.2 7.8 6.5 0.3 5.1 2 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 EAY02288.1 - 0.16 11.8 0.9 0.9 9.4 0.1 2.6 3 0 0 3 3 3 0 VHS domain MetOD1 PF18546.1 EAY02288.1 - 0.28 11.1 2.5 4.4 7.3 0.0 3.5 3 1 0 3 3 3 0 Metanogen output domain 1 Flavodoxin_2 PF02525.17 EAY02289.1 - 1.5e-30 106.4 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_2 PF02525.17 EAY02290.1 - 1.5e-29 103.2 0.2 1.7e-29 102.9 0.2 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold ATP-synt_F PF01990.17 EAY02291.1 - 0.18 12.2 0.0 29 5.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Rubrerythrin PF02915.17 EAY02292.1 - 1.9e-23 83.4 1.6 2.6e-23 82.9 1.6 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EAY02292.1 - 1.4e-07 31.5 0.3 1.7e-07 31.3 0.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain zf-C2HC5 PF06221.13 EAY02292.1 - 0.013 15.5 0.5 0.029 14.4 0.3 1.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type HypA PF01155.19 EAY02292.1 - 0.013 15.5 0.9 0.077 13.0 0.5 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EAY02292.1 - 0.036 14.1 1.1 0.07 13.2 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon PyrI_C PF02748.15 EAY02292.1 - 0.072 13.0 0.2 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Vps16_N PF04841.13 EAY02293.1 - 3e-08 32.8 0.0 4.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region DUF3447 PF11929.8 EAY02294.1 - 3.7e-37 126.1 8.0 3.7e-37 126.1 8.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY02294.1 - 0.00019 21.9 0.2 0.079 13.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EAY02295.1 - 3e-116 380.2 73.6 2.8e-16 59.9 1.4 6.7 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02295.1 - 6.5e-101 326.8 27.1 4.2e-09 36.5 0.0 11.1 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 EAY02295.1 - 1.6e-94 309.2 31.1 6.8e-15 55.2 0.4 11.0 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02295.1 - 1.8e-79 252.1 23.2 3e-06 27.1 0.0 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 EAY02295.1 - 8.3e-66 217.2 35.1 9.4e-11 41.7 0.2 7.7 5 1 4 9 9 9 8 Ankyrin repeats (many copies) DUF1293 PF06950.11 EAY02295.1 - 1.3e-07 31.7 0.0 4 7.6 0.0 4.6 1 1 2 4 4 4 1 Protein of unknown function (DUF1293) DUF2002 PF09400.10 EAY02295.1 - 7.3e-06 26.0 1.3 46 4.1 0.0 7.0 1 1 8 9 9 9 0 Protein of unknown function (DUF2002) QRPTase_C PF01729.19 EAY02295.1 - 1.2e-05 25.2 9.1 1.9 8.2 0.2 4.8 1 1 5 6 6 6 4 Quinolinate phosphoribosyl transferase, C-terminal domain Ribosomal_S6 PF01250.17 EAY02295.1 - 2e-05 24.8 10.0 0.98 9.7 0.1 8.2 1 1 9 10 10 10 1 Ribosomal protein S6 zf-CCHC_5 PF14787.6 EAY02295.1 - 0.0008 19.1 6.8 1.7e+02 2.0 0.0 6.8 7 0 0 7 7 7 0 GAG-polyprotein viral zinc-finger Aft1_HRR PF11787.8 EAY02295.1 - 0.0077 17.4 7.8 87 4.4 1.1 6.3 4 2 0 4 4 4 0 Aft1 HRR domain BtrH_N PF14399.6 EAY02295.1 - 0.044 14.0 3.5 1.1e+02 3.0 0.0 6.1 6 2 1 8 8 7 0 Butirosin biosynthesis protein H, N-terminal Yos9_DD PF17880.1 EAY02295.1 - 0.08 13.1 8.0 42 4.3 0.1 5.6 4 1 1 5 5 5 0 Yos9 dimerzation domain Env-gp36 PF09590.10 EAY02295.1 - 0.16 10.3 3.6 5.1 5.4 0.0 3.4 1 1 2 4 4 4 0 Lentivirus surface glycoprotein Shigella_OspC PF06128.11 EAY02295.1 - 0.3 10.8 8.9 1.3 8.7 0.6 3.9 1 1 4 5 5 5 0 Shigella flexneri OspC protein DUF5448 PF17526.2 EAY02295.1 - 0.96 9.6 4.4 70 3.6 0.0 5.0 1 1 8 10 10 10 0 Family of unknown function (DUF5448) BDHCT PF08072.11 EAY02296.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 BDHCT (NUC031) domain DUF3447 PF11929.8 EAY02297.1 - 1.9e-39 133.5 7.7 1.9e-39 133.5 7.7 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY02297.1 - 2.2e-05 24.9 2.4 0.00081 19.9 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02298.1 - 8.1e-08 32.7 0.2 6.6e-07 29.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02298.1 - 8.4e-08 32.7 0.3 2e-07 31.5 0.3 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02298.1 - 7.4e-06 26.2 0.1 0.0009 19.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAY02298.1 - 0.00035 20.8 0.0 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02298.1 - 0.0011 19.2 0.1 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAY02299.1 - 8e-16 58.2 0.7 2.5e-08 34.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY02299.1 - 1.8e-15 56.6 0.9 9.8e-06 25.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAY02299.1 - 3.6e-11 43.5 0.7 4.6e-11 43.1 0.7 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02299.1 - 5.2e-10 38.7 1.7 0.00054 20.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EAY02299.1 - 1.8e-06 28.1 0.1 5e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) SlyX PF04102.12 EAY02300.1 - 5.7e-06 26.9 26.3 0.00014 22.4 1.9 4.4 1 1 3 4 4 4 2 SlyX Tektin PF03148.14 EAY02300.1 - 0.00025 19.9 16.1 0.00025 19.9 16.1 2.2 1 1 1 2 2 2 1 Tektin family Fez1 PF06818.15 EAY02300.1 - 0.00025 21.6 27.3 0.009 16.5 9.8 2.3 1 1 1 2 2 2 2 Fez1 FliJ PF02050.16 EAY02300.1 - 0.00031 20.9 24.7 0.47 10.7 0.6 3.2 2 1 1 3 3 3 3 Flagellar FliJ protein MscS_porin PF12795.7 EAY02300.1 - 0.0023 17.5 35.6 0.0066 16.0 16.0 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain CEP209_CC5 PF16574.5 EAY02300.1 - 0.0046 17.1 24.1 0.0067 16.6 10.1 3.0 1 1 1 2 2 2 1 Coiled-coil region of centrosome protein CE290 CEP63 PF17045.5 EAY02300.1 - 0.0056 16.6 26.5 0.014 15.3 26.5 1.6 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa Filament PF00038.21 EAY02300.1 - 0.0059 16.2 18.3 0.0059 16.2 18.3 3.0 1 1 2 3 3 3 2 Intermediate filament protein Lebercilin PF15619.6 EAY02300.1 - 0.0061 16.2 28.2 0.009 15.7 20.5 2.4 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 EAY02300.1 - 0.0061 17.0 31.9 0.14 12.6 4.5 3.4 1 1 2 3 3 3 2 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 EAY02300.1 - 0.0067 16.4 33.2 0.021 14.8 2.2 4.3 3 1 2 5 5 4 2 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 EAY02300.1 - 0.0084 16.7 26.6 0.072 13.7 3.5 4.4 2 2 2 4 4 4 1 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 EAY02300.1 - 0.0084 16.3 33.6 0.049 13.8 3.0 3.5 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EAY02300.1 - 0.012 14.5 31.3 0.19 10.6 22.4 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.18 EAY02300.1 - 0.019 15.3 16.0 0.11 12.8 0.5 5.2 2 2 3 5 5 5 0 TSC-22/dip/bun family Ax_dynein_light PF10211.9 EAY02300.1 - 0.035 14.1 30.9 0.032 14.2 11.7 2.8 2 1 1 3 3 3 0 Axonemal dynein light chain ATG16 PF08614.11 EAY02300.1 - 0.035 14.3 29.7 0.55 10.4 13.9 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 EAY02300.1 - 0.039 13.8 3.6 24 5.0 0.0 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat HMMR_N PF15905.5 EAY02300.1 - 0.063 12.8 34.3 0.14 11.6 22.3 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal APC_N_CC PF16689.5 EAY02300.1 - 0.11 12.6 7.2 17 5.5 0.1 4.2 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Trimer_CC PF08954.11 EAY02300.1 - 0.19 11.3 6.3 2.7 7.6 0.1 3.4 3 0 0 3 3 3 0 Trimerisation motif DUF4140 PF13600.6 EAY02300.1 - 0.28 11.7 19.7 1.4 9.4 1.1 4.2 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 EAY02300.1 - 0.32 11.1 17.8 2.9 8.1 0.7 4.5 1 1 3 4 4 4 0 Basic region leucine zipper DivIC PF04977.15 EAY02300.1 - 0.41 10.4 29.1 0.22 11.3 1.5 4.6 1 1 3 4 4 4 0 Septum formation initiator Cep57_CLD_2 PF14197.6 EAY02300.1 - 0.51 10.5 16.3 0.98 9.6 7.7 4.0 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 BRE1 PF08647.11 EAY02300.1 - 0.52 10.4 29.9 0.58 10.3 9.8 3.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 EAY02300.1 - 0.9 8.8 26.1 1.2 8.4 9.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 EAY02300.1 - 0.93 8.9 28.6 1.1 8.7 19.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF1192 PF06698.11 EAY02300.1 - 1.1 9.4 7.4 0.59 10.2 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Med9 PF07544.13 EAY02300.1 - 1.1 9.4 27.6 0.13 12.3 10.2 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3987 PF13148.6 EAY02300.1 - 1.7 7.5 7.0 31 3.4 7.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) Mt_ATP-synt_D PF05873.12 EAY02300.1 - 1.8 8.4 16.5 0.28 11.0 4.3 3.7 1 1 3 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) CorA PF01544.18 EAY02300.1 - 1.8 7.8 18.2 0.52 9.6 12.4 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TPD52 PF04201.15 EAY02300.1 - 2.1 8.0 14.7 0.067 12.8 5.0 2.8 1 1 2 3 3 3 0 Tumour protein D52 family DUF5082 PF16888.5 EAY02300.1 - 2.9 8.2 36.6 0.28 11.5 21.5 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 EAY02300.1 - 3.7 7.9 24.0 6.7 7.1 3.3 4.0 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) CCDC-167 PF15188.6 EAY02300.1 - 4.8 7.6 21.5 0.42 11.0 1.4 3.7 2 1 0 4 4 3 0 Coiled-coil domain-containing protein 167 KELK PF15796.5 EAY02300.1 - 5.8 7.4 21.9 2.7 8.5 1.3 4.1 2 1 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Csm1_N PF18504.1 EAY02300.1 - 5.9 7.3 27.3 5.7 7.4 2.2 4.8 1 1 1 4 4 4 0 Csm1 N-terminal domain DUF2400 PF09674.10 EAY02300.1 - 7.9 6.4 10.4 0.65 10.0 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Ank_4 PF13637.6 EAY02301.1 - 2.7e-81 267.0 29.9 5.9e-10 39.5 0.1 11.6 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 EAY02301.1 - 2e-80 262.0 18.3 1.2e-06 28.6 0.0 12.0 12 0 0 12 12 12 12 Ankyrin repeat Ank_2 PF12796.7 EAY02301.1 - 1e-71 237.5 36.2 1.7e-18 66.9 1.2 7.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02301.1 - 3.3e-58 186.8 20.6 2.9e-06 27.2 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAY02301.1 - 1.7e-53 178.0 22.5 5.6e-09 36.1 0.0 8.1 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 EAY02301.1 - 0.0012 19.1 6.8 7.5 6.9 0.2 5.7 2 2 6 8 8 8 1 Ribosomal protein S6 BRCT PF00533.26 EAY02301.1 - 0.015 15.7 4.8 93 3.5 0.3 6.4 4 2 2 6 6 6 0 BRCA1 C Terminus (BRCT) domain RL PF17797.1 EAY02301.1 - 0.018 15.0 6.8 0.25 11.3 0.1 4.5 5 0 0 5 5 5 0 RL domain MHC_I_2 PF14586.6 EAY02301.1 - 0.029 14.2 2.4 3.2 7.6 0.2 4.3 2 1 3 5 5 5 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 ThiS-like PF14453.6 EAY02301.1 - 0.16 12.1 8.9 1 9.5 1.3 3.6 3 0 0 3 3 3 0 ThiS-like ubiquitin MTES_1575 PF18741.1 EAY02301.1 - 0.19 11.9 1.2 31 4.8 0.0 4.3 4 2 1 5 5 5 0 REase_MTES_1575 DUF4147 PF13660.6 EAY02301.1 - 0.43 10.1 1.9 28 4.2 0.0 3.8 5 1 0 5 5 5 0 Domain of unknown function (DUF4147) DUF3447 PF11929.8 EAY02302.1 - 6.3e-34 115.8 8.9 7.8e-34 115.5 6.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EAY02302.1 - 0.013 16.1 0.1 0.07 13.7 0.1 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02302.1 - 0.022 15.3 0.2 0.2 12.3 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02302.1 - 0.13 12.6 0.1 64 4.0 0.0 3.3 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Inositol_P PF00459.25 EAY02303.1 - 2.2e-32 112.7 0.0 3.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family DUF3827 PF12877.7 EAY02303.1 - 0.0034 15.8 0.1 0.0049 15.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Ank_4 PF13637.6 EAY02304.1 - 7.5e-22 77.4 0.6 2.5e-15 56.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02304.1 - 1.9e-20 72.6 2.3 5e-14 52.2 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02304.1 - 1.8e-18 64.7 1.5 2e-07 30.8 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAY02304.1 - 2e-18 66.7 0.2 3.8e-18 65.9 0.1 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02304.1 - 3.9e-17 61.8 0.7 3.8e-06 27.1 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat HP0268 PF18618.1 EAY02304.1 - 0.027 14.9 1.8 0.047 14.1 1.8 1.4 1 0 0 1 1 1 0 HP0268 Flu_NS2 PF00601.19 EAY02304.1 - 0.054 13.8 0.5 1.4 9.3 0.1 2.8 3 1 0 3 3 3 0 Influenza non-structural protein (NS2) YbaJ PF10757.9 EAY02305.1 - 0.0061 17.1 0.2 0.045 14.3 0.2 2.6 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ DUF5600 PF18150.1 EAY02305.1 - 0.18 12.4 1.9 0.58 10.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) LRR_4 PF12799.7 EAY02307.1 - 8.3e-20 70.6 14.6 8.3e-10 38.8 0.9 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAY02307.1 - 1.4e-16 60.5 5.9 1.9e-12 47.0 1.6 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAY02307.1 - 2.3e-12 46.5 10.7 2.3e-06 27.2 0.3 3.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EAY02307.1 - 7.8e-06 25.5 10.1 0.0079 16.2 0.3 6.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 EAY02307.1 - 0.045 14.3 11.5 16 6.5 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat YlbE PF14003.6 EAY02307.1 - 0.48 10.9 3.9 1.7 9.1 0.0 3.3 3 0 0 3 3 3 0 YlbE-like protein Drf_DAD PF06345.11 EAY02308.1 - 0.029 14.4 0.2 0.058 13.5 0.2 1.5 1 0 0 1 1 1 0 DRF Autoregulatory Domain OAM_alpha PF16552.5 EAY02308.1 - 0.051 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Ank_4 PF13637.6 EAY02309.1 - 8.3e-103 335.6 14.9 4.7e-11 43.0 0.0 12.8 4 4 9 13 13 13 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02309.1 - 1.7e-94 310.5 53.9 7e-16 58.6 2.6 7.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02309.1 - 1.4e-88 287.8 6.8 7.3e-06 26.2 0.0 14.1 14 0 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.6 EAY02309.1 - 1.5e-72 230.9 15.9 5e-05 23.4 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 EAY02309.1 - 3.3e-69 228.0 8.6 8.3e-10 38.7 0.0 7.4 6 1 1 7 7 7 7 Ankyrin repeats (many copies) DUF3126 PF11324.8 EAY02309.1 - 1.6e-05 24.6 0.9 28 4.6 0.0 7.8 9 0 0 9 9 9 0 Protein of unknown function (DUF3126) YcxB PF14317.6 EAY02309.1 - 3.6e-05 23.4 0.5 1.7 8.4 0.0 5.3 7 0 0 7 7 7 1 YcxB-like protein Ion_trans_N PF08412.10 EAY02309.1 - 6.8e-05 22.4 0.5 52 3.6 0.0 5.2 5 0 0 5 5 5 0 Ion transport protein N-terminal TMEM72 PF16054.5 EAY02309.1 - 0.00012 21.9 0.0 7.3 6.2 0.0 4.7 4 0 0 4 4 4 1 Transmembrane protein family 72 Aldolase PF01081.19 EAY02309.1 - 0.00015 21.2 8.6 0.56 9.6 0.3 4.5 2 2 2 4 4 4 2 KDPG and KHG aldolase DUF3447 PF11929.8 EAY02309.1 - 0.00033 20.6 0.4 0.00033 20.6 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) CCDC84 PF14968.6 EAY02309.1 - 0.0058 16.3 18.4 4.6 6.8 3.0 5.0 1 1 4 5 5 4 2 Coiled coil protein 84 Ad_Cy_reg PF16701.5 EAY02309.1 - 0.012 15.4 0.1 57 3.4 0.0 4.4 5 0 0 5 5 5 0 Adenylate cyclase regulatory domain MTES_1575 PF18741.1 EAY02309.1 - 0.014 15.6 2.6 45 4.3 0.0 5.9 1 1 6 9 9 9 0 REase_MTES_1575 SAB PF04382.13 EAY02309.1 - 0.53 10.4 19.5 1.1e+02 3.0 0.0 8.4 11 0 0 11 11 11 0 SAB domain THDPS_N PF14790.6 EAY02309.1 - 0.56 10.0 8.3 34 4.2 0.2 4.4 2 2 3 5 5 5 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF3718 PF12514.8 EAY02309.1 - 0.76 10.0 19.3 0.7 10.1 0.1 7.2 7 2 2 9 9 8 0 Protein of unknown function (DUF3718) DUF2149 PF09919.9 EAY02309.1 - 1 9.7 7.8 1.4e+02 2.8 0.0 5.9 2 2 5 8 8 8 0 Uncharacterized conserved protein (DUF2149) DUF3447 PF11929.8 EAY02310.1 - 1.5e-19 69.7 0.1 8.6e-19 67.3 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) RRM_1 PF00076.22 EAY02311.1 - 4.1e-06 26.5 1.3 0.007 16.2 0.1 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 EAY02312.1 - 7.1e-17 61.8 4.9 2e-05 25.1 1.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02312.1 - 1e-14 54.7 1.9 0.011 16.3 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02312.1 - 1.9e-11 44.0 6.0 0.45 10.9 0.0 7.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02312.1 - 1.6e-07 31.0 9.2 2.4 9.0 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 EAY02312.1 - 1.2e-05 25.5 0.1 7.8 7.1 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat Arf PF00025.21 EAY02313.1 - 1.5e-36 125.5 0.0 1.7e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EAY02313.1 - 5e-09 36.0 0.0 7.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EAY02313.1 - 1.5e-07 31.4 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAY02313.1 - 2.9e-07 30.2 0.0 6.5e-07 29.1 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAY02313.1 - 5.2e-07 29.3 0.0 6.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAY02313.1 - 5.8e-07 29.8 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAY02313.1 - 0.00015 21.2 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAY02313.1 - 0.00018 21.4 0.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAY02313.1 - 0.00038 19.7 0.7 0.005 16.0 0.1 2.4 1 1 0 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 EAY02313.1 - 0.0022 18.2 0.0 0.0072 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAY02313.1 - 0.013 15.4 0.0 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EAY02313.1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EAY02313.1 - 0.047 12.7 0.3 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EAY02313.1 - 0.06 13.1 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PurL_C PF16904.5 EAY02313.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus Glucosamine_iso PF01182.20 EAY02313.1 - 0.21 11.4 0.0 1.4 8.7 0.0 1.9 2 0 0 2 2 2 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_77 PF02446.17 EAY02314.1 - 5.3e-09 35.5 0.0 5.9e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Cys_Met_Meta_PP PF01053.20 EAY02314.1 - 0.017 13.7 0.0 0.017 13.7 0.0 1.0 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Trypan_PARP PF05887.11 EAY02315.1 - 0.00019 21.4 68.0 0.047 13.7 24.3 3.3 1 1 2 3 3 3 3 Procyclic acidic repetitive protein (PARP) Insulin_TMD PF17870.1 EAY02315.1 - 0.0011 19.0 0.6 0.0021 18.1 0.6 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment T4SS_CagC PF16943.5 EAY02315.1 - 0.01 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 Cag pathogenicity island, type IV secretory system EphA2_TM PF14575.6 EAY02315.1 - 0.02 15.8 0.1 0.045 14.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAY02315.1 - 0.031 14.2 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family FeoB_associated PF12669.7 EAY02315.1 - 0.56 10.6 1.8 1.1 9.7 1.8 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4108 PF13390.6 EAY02317.1 - 6.9e-70 233.5 11.4 7.9e-70 233.3 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Gly-zipper_Omp PF13488.6 EAY02318.1 - 0.013 15.5 7.7 0.013 15.5 7.7 1.5 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 EAY02318.1 - 0.3 11.4 4.2 0.49 10.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Pox_A32 PF04665.12 EAY02319.1 - 0.00028 20.5 2.0 0.00031 20.3 1.1 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY02319.1 - 0.0069 16.4 0.5 0.019 15.0 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAY02319.1 - 0.023 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4795 PF16043.5 EAY02320.1 - 1.4 8.5 19.4 4.1 7.0 5.2 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Acetyltransf_1 PF00583.25 EAY02322.1 - 2.1e-09 37.6 0.1 3e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAY02322.1 - 1.5e-05 25.4 0.7 3.5e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAY02322.1 - 2.8e-05 24.1 0.1 6e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAY02322.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EAY02322.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Translin PF01997.16 EAY02323.1 - 0.0099 15.9 2.1 0.0099 15.9 2.1 1.7 2 0 0 2 2 2 1 Translin family DUF1216 PF06746.11 EAY02323.1 - 0.013 15.5 10.1 0.013 15.5 10.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Mis14 PF08641.12 EAY02323.1 - 0.076 13.3 3.1 0.08 13.3 1.1 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Flagellin_N PF00669.20 EAY02323.1 - 0.097 12.8 3.2 0.099 12.8 1.4 1.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region PMC2NT PF08066.12 EAY02323.1 - 2.9 8.6 5.7 1.6 9.5 0.4 2.7 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Syntaxin_2 PF14523.6 EAY02323.1 - 7.3 7.0 11.6 6.9 7.1 4.5 2.8 1 1 1 2 2 2 0 Syntaxin-like protein FAP206 PF12018.8 EAY02324.1 - 5.4e-53 180.3 0.1 1.6e-52 178.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function dCache_1 PF02743.18 EAY02325.1 - 1.6e-08 34.7 1.7 3.4e-08 33.6 1.7 1.6 1 0 0 1 1 1 1 Cache domain TFIID-18kDa PF02269.16 EAY02326.1 - 0.0013 18.7 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EAY02326.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Ribosomal_L44 PF00935.19 EAY02327.1 - 7.1e-25 87.3 9.9 7.1e-25 87.3 9.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Rpr2 PF04032.16 EAY02327.1 - 0.11 12.8 6.1 0.32 11.3 6.1 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 EAY02327.1 - 0.12 12.9 13.7 2 9.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 EAY02327.1 - 1.1 9.6 9.1 0.23 11.7 1.3 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.11 EAY02327.1 - 1.1 9.5 10.7 0.1 12.8 1.6 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.13 EAY02327.1 - 2.3 8.3 15.9 3.6 7.7 1.6 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Gly-zipper_Omp PF13488.6 EAY02328.1 - 0.0059 16.6 9.0 0.01 15.8 9.0 1.4 1 0 0 1 1 1 1 Glycine zipper PsbY PF06298.11 EAY02328.1 - 0.074 13.0 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) Zincin_2 PF10103.9 EAY02328.1 - 0.083 12.1 0.0 0.096 11.9 0.0 1.0 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF1269 PF06897.12 EAY02328.1 - 0.32 11.3 4.8 0.5 10.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PT-VENN PF04829.13 EAY02328.1 - 1.3 9.2 5.7 2.1 8.5 5.7 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pox_A32 PF04665.12 EAY02329.1 - 3e-05 23.6 3.1 3.4e-05 23.4 2.3 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein tRNA_synt_1c_R1 PF04558.15 EAY02329.1 - 0.0042 17.1 1.3 0.0072 16.3 0.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_trans_1_3 PF13528.6 EAY02329.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1722 PF08349.11 EAY02329.1 - 0.054 13.8 1.7 0.13 12.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3839 PF12943.7 EAY02331.1 - 6e-124 412.3 8.8 6.9e-124 412.1 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) NTP_transf_6 PF06042.11 EAY02331.1 - 0.041 13.7 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase PA28_beta PF02252.18 EAY02331.1 - 0.082 12.6 3.3 0.18 11.5 1.3 2.3 2 1 0 2 2 2 0 Proteasome activator pa28 beta subunit DUF2547 PF10818.8 EAY02331.1 - 0.14 13.1 0.9 4.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) DUF4107 PF13389.6 EAY02333.1 - 7.9e-73 244.0 3.8 1e-72 243.6 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) LysM PF01476.20 EAY02335.1 - 4.7e-05 23.4 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 LysM domain Metallophos PF00149.28 EAY02336.1 - 8e-19 69.0 0.0 1.3e-18 68.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 EAY02337.1 - 4.9e-11 43.1 5.5 5.4e-05 23.7 0.2 4.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02337.1 - 3e-07 30.2 8.5 4.2 8.3 0.0 8.6 8 1 1 9 9 9 1 Ankyrin repeat DUF3447 PF11929.8 EAY02337.1 - 3e-06 27.1 0.1 3e-06 27.1 0.1 4.2 3 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EAY02337.1 - 1.1e-05 25.9 8.4 0.048 14.3 0.0 6.3 5 2 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02337.1 - 0.015 15.6 1.0 96 3.5 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) TMEM154 PF15102.6 EAY02338.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 EAY02338.1 - 0.023 13.5 0.1 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 EAY02338.1 - 0.051 14.4 0.0 0.094 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S8 PF00082.22 EAY02339.1 - 2.8e-38 131.9 0.1 5.7e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 Subtilase family CBM_35 PF16990.5 EAY02339.1 - 0.054 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) 7TMR-DISMED2 PF07696.11 EAY02342.1 - 0.00094 19.3 0.0 0.0036 17.4 0.0 1.9 1 1 1 2 2 2 1 7TMR-DISM extracellular 2 DUF4011 PF13195.6 EAY02343.1 - 0.0063 16.5 0.7 0.016 15.1 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4011) tRNA_anti-codon PF01336.25 EAY02344.1 - 0.022 14.7 0.2 4.2 7.4 0.0 3.7 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Cadherin PF00028.17 EAY02344.1 - 0.31 11.5 7.2 1.6 9.2 0.4 4.8 5 0 0 5 5 5 0 Cadherin domain TMEM154 PF15102.6 EAY02345.1 - 0.007 16.3 0.5 0.013 15.4 0.5 1.4 1 0 0 1 1 1 1 TMEM154 protein family Stevor PF17410.2 EAY02345.1 - 0.017 14.7 0.4 0.028 14.0 0.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRR19-TM PF15176.6 EAY02345.1 - 0.038 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CBM_4_9 PF02018.17 EAY02345.1 - 0.063 13.6 2.5 0.22 11.8 0.4 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain Furin-like_2 PF15913.5 EAY02346.1 - 4.1e-35 120.2 135.5 1.6e-08 34.7 9.0 8.8 1 1 8 9 9 9 8 Furin-like repeat, cysteine-rich Furin-like PF00757.20 EAY02346.1 - 0.00096 19.0 139.7 2.8 7.8 37.9 6.4 1 1 5 6 6 6 4 Furin-like cysteine rich region DUF4215 PF13948.6 EAY02346.1 - 0.0067 16.8 80.2 0.025 15.0 21.0 9.6 4 4 5 9 9 9 4 Domain of unknown function (DUF4215) Fer4_4 PF12800.7 EAY02346.1 - 0.033 14.7 1.1 0.033 14.7 1.1 17.7 10 5 1 11 11 11 0 4Fe-4S binding domain VSP PF03302.13 EAY02346.1 - 0.65 8.8 119.7 0.16 10.8 40.0 5.9 1 1 3 4 4 4 0 Giardia variant-specific surface protein Phage_holin_2_2 PF10746.9 EAY02347.1 - 0.076 12.7 0.0 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II Ank_4 PF13637.6 EAY02348.1 - 7.3e-46 154.0 12.6 8.4e-14 51.7 0.2 7.6 4 1 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EAY02348.1 - 3.1e-44 147.5 8.9 3.7e-08 33.4 0.0 6.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_2 PF12796.7 EAY02348.1 - 1.8e-41 140.6 20.0 1.3e-17 64.1 5.3 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EAY02348.1 - 3.4e-34 116.6 7.4 3.4e-34 116.6 7.4 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EAY02348.1 - 6.4e-33 109.1 12.1 1.6e-05 24.9 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAY02348.1 - 7e-27 93.1 3.0 4.2e-10 39.7 0.1 5.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) HEM4 PF02602.15 EAY02348.1 - 0.099 12.0 0.2 1.2 8.5 0.2 2.3 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD CCDC84 PF14968.6 EAY02348.1 - 6.4 6.3 9.1 26 4.3 1.4 3.0 1 1 2 3 3 3 0 Coiled coil protein 84 EF-hand_7 PF13499.6 EAY02349.1 - 1e-05 25.9 0.1 1.8e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EAY02349.1 - 0.00013 21.6 0.4 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EAY02349.1 - 0.0011 18.3 0.2 0.0055 16.2 0.0 2.2 2 0 0 2 2 2 1 EF hand ANAPC4_WD40 PF12894.7 EAY02349.1 - 0.031 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_13 PF17958.1 EAY02349.1 - 0.032 14.0 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.32 EAY02350.1 - 3.7e-05 24.4 4.2 2 9.4 0.1 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAY02350.1 - 0.011 16.1 1.1 9.8 6.6 0.0 4.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Beta_elim_lyase PF01212.21 EAY02351.1 - 3.3e-90 302.3 0.0 3.9e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase DUF5305 PF17231.2 EAY02351.1 - 0.0009 18.7 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) OKR_DC_1 PF01276.20 EAY02351.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 EAY02351.1 - 0.0043 16.3 0.0 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DUF4224 PF13986.6 EAY02351.1 - 0.15 12.0 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Ribosomal_L6 PF00347.23 EAY02352.1 - 8.5e-10 39.2 0.9 0.00042 20.9 0.0 3.1 2 1 1 3 3 3 3 Ribosomal protein L6 LCCL PF03815.19 EAY02353.1 - 0.00013 22.0 0.5 0.02 15.0 0.1 2.3 2 0 0 2 2 2 2 LCCL domain Rxt3 PF08642.10 EAY02353.1 - 0.0035 18.1 0.0 0.021 15.6 0.0 2.0 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 Pullulanase_Ins PF18494.1 EAY02354.1 - 0.0082 16.6 1.1 0.02 15.4 0.2 2.1 2 0 0 2 2 2 1 Pullulanase Ins domain C2 PF00168.30 EAY02355.1 - 6.5e-108 354.0 20.6 3.1e-22 78.8 0.3 6.9 6 0 0 6 6 6 6 C2 domain Ank_2 PF12796.7 EAY02355.1 - 1e-38 131.8 3.3 1.6e-07 31.8 0.0 7.3 3 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAY02355.1 - 2.9e-33 110.2 2.1 0.0009 19.5 0.0 10.3 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 EAY02355.1 - 7.1e-31 106.2 2.3 2.4e-05 24.8 0.0 9.6 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAY02355.1 - 2.8e-26 91.2 0.5 8.5e-05 22.8 0.1 7.7 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAY02355.1 - 2.5e-23 81.4 6.3 0.00015 22.1 0.0 10.7 11 1 0 11 11 11 4 Ankyrin repeat DUF1262 PF06880.11 EAY02355.1 - 0.013 15.9 2.7 5.7 7.4 0.2 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1262) SafA PF17073.5 EAY02355.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.8 1 0 0 1 1 1 0 Two-component-system connector protein Ank_5 PF13857.6 EAY02356.1 - 1.3e-05 25.4 0.0 0.056 13.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY02356.1 - 0.00016 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EAY02356.1 - 0.035 14.7 0.0 1.9 9.2 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02356.1 - 0.07 13.7 0.0 0.36 11.4 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Beta_helix PF13229.6 EAY02357.1 - 4.6e-16 59.1 35.7 1.4e-15 57.5 12.9 3.4 1 1 2 3 3 3 2 Right handed beta helix region zf-C3HC4_3 PF13920.6 EAY02357.1 - 2e-11 43.6 8.9 2e-11 43.6 8.9 4.9 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAY02357.1 - 1.1e-10 41.2 9.7 1.1e-10 41.2 9.7 3.9 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAY02357.1 - 3.1e-08 33.8 7.2 3.1e-08 33.8 7.2 5.5 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 EAY02357.1 - 1.5e-07 31.2 7.4 1.5e-07 31.2 7.4 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAY02357.1 - 1.8e-07 30.9 7.4 1.8e-07 30.9 7.4 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAY02357.1 - 0.00014 21.8 7.8 0.00014 21.8 7.8 4.7 4 1 1 5 5 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAY02357.1 - 0.00021 21.2 6.8 0.00021 21.2 6.8 4.7 5 0 0 5 5 5 1 zinc-RING finger domain NosD PF05048.13 EAY02357.1 - 0.0031 16.8 5.8 0.0031 16.8 5.8 2.3 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) zf-rbx1 PF12678.7 EAY02357.1 - 0.02 15.2 5.1 0.02 15.2 5.1 4.5 3 0 0 3 3 2 0 RING-H2 zinc finger domain Pectate_lyase_3 PF12708.7 EAY02357.1 - 6.1 6.6 18.5 0.24 11.2 0.4 3.2 1 1 2 3 3 3 0 Pectate lyase superfamily protein RhoGAP PF00620.27 EAY02359.1 - 1.2e-24 86.9 0.0 3.4e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 EAY02359.1 - 4.2e-18 65.8 0.1 1.4e-17 64.2 0.2 1.8 2 0 0 2 2 2 1 MyTH4 domain DUF4437 PF14499.6 EAY02360.1 - 0.00064 18.9 0.2 0.0023 17.1 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) DUF1664 PF07889.12 EAY02360.1 - 0.019 15.0 1.7 0.019 15.0 1.7 8.3 6 3 5 11 11 11 0 Protein of unknown function (DUF1664) RseA_C PF03873.13 EAY02360.1 - 0.027 14.7 0.4 4.3 7.7 0.1 3.2 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Baculo_PEP_C PF04513.12 EAY02360.1 - 0.16 12.0 42.2 0.94 9.5 2.9 7.8 6 2 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tape_meas_lam_C PF09718.10 EAY02360.1 - 0.91 9.7 7.6 0.58 10.3 0.6 3.8 4 0 0 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Acylphosphatase PF00708.18 EAY02361.1 - 8.3e-14 51.8 0.3 1.6e-13 50.9 0.2 1.5 1 1 1 2 2 2 1 Acylphosphatase Thioredoxin PF00085.20 EAY02362.1 - 1.1e-17 63.9 0.1 1.6e-16 60.2 0.1 2.6 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EAY02362.1 - 2.7e-13 50.2 7.9 3.9e-13 49.7 3.3 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAY02362.1 - 5.7e-05 23.5 0.1 0.0019 18.7 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAY02362.1 - 0.0026 18.0 11.2 2.5 8.5 2.1 4.3 2 2 1 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 EAY02362.1 - 0.021 15.0 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like OppC_N PF12911.7 EAY02362.1 - 0.94 9.5 4.3 1.3 9.1 2.7 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Gly_rich PF12810.7 EAY02363.1 - 3.7e-18 66.3 36.1 4.3e-18 66.1 36.1 1.0 1 0 0 1 1 1 1 Glycine rich protein LRR_5 PF13306.6 EAY02364.1 - 2.5e-50 169.7 34.5 1.1e-21 77.1 7.0 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02364.1 - 1e-05 25.2 1.1 0.2 11.5 0.0 4.3 2 1 2 4 4 4 3 Leucine rich repeat FNIP PF05725.12 EAY02364.1 - 0.027 14.6 0.2 0.027 14.6 0.2 4.2 5 1 0 5 5 5 0 FNIP Repeat TMEM154 PF15102.6 EAY02365.1 - 0.00015 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 EAY02365.1 - 0.0025 18.1 0.4 0.0079 16.5 0.0 2.0 2 0 0 2 2 2 1 Orf78 (ac78) TMEM132D_C PF15706.5 EAY02365.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PRIMA1 PF16101.5 EAY02365.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 OSTbeta PF15048.6 EAY02365.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Herpes_gE PF02480.16 EAY02365.1 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAY02365.1 - 0.019 15.8 0.0 0.046 14.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 EAY02365.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein SIT PF15330.6 EAY02365.1 - 0.024 15.1 0.4 0.24 11.9 0.4 2.4 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2269 PF10027.9 EAY02365.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ECSCR PF15820.5 EAY02365.1 - 0.034 14.0 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4330 PF14221.6 EAY02365.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF5385 PF17359.2 EAY02365.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) TssO PF17561.2 EAY02365.1 - 0.97 9.5 5.3 0.28 11.3 0.2 2.5 3 0 0 3 3 3 0 Type VI secretion system, TssO UQ_con PF00179.26 EAY02366.1 - 1.2e-40 138.4 0.7 1.4e-40 138.2 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAY02366.1 - 0.0016 18.7 0.6 0.0023 18.2 0.6 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 EAY02366.1 - 0.014 15.1 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 EAY02366.1 - 0.084 12.7 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 EAY02367.1 - 2e-64 217.5 0.0 4.6e-64 216.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02367.1 - 5.7e-37 127.4 0.0 8.9e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY02367.1 - 1.4e-06 27.9 0.0 3.5e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAY02367.1 - 0.00037 20.5 0.1 0.0016 18.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAY02367.1 - 0.0013 17.9 0.1 0.0046 16.1 0.0 1.9 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EAY02367.1 - 0.0018 17.3 2.3 0.052 12.5 2.3 2.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAY02367.1 - 0.004 16.0 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAY02367.1 - 0.0067 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LUC7 PF03194.15 EAY02368.1 - 1.6e-40 139.3 6.0 2.2e-40 138.9 6.0 1.1 1 0 0 1 1 1 1 LUC7 N_terminus HOOK PF05622.12 EAY02369.1 - 0.00033 19.0 11.5 0.00033 19.0 11.5 4.0 3 1 1 4 4 4 1 HOOK protein YscO PF07321.12 EAY02369.1 - 0.00058 19.8 6.5 0.00058 19.8 6.5 4.3 4 1 0 4 4 4 1 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 EAY02369.1 - 0.004 17.2 0.6 0.004 17.2 0.6 6.1 4 2 1 5 5 5 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EAY02369.1 - 0.053 13.6 56.1 0.18 11.9 2.0 4.8 3 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 EAY02369.1 - 3.5 7.6 14.1 12 6.0 0.2 4.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat RasGAP_C PF03836.15 EAY02369.1 - 5.5 7.1 37.7 2.5 8.3 0.8 4.6 3 1 1 4 4 4 0 RasGAP C-terminus DUF4326 PF14216.6 EAY02370.1 - 0.1 13.4 2.6 59 4.5 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4326) Luteo_coat PF00894.18 EAY02370.1 - 0.26 11.2 0.7 33 4.4 0.0 2.9 3 0 0 3 3 3 0 Luteovirus coat protein DUF5491 PF17595.2 EAY02370.1 - 0.27 11.6 3.5 1.6e+02 2.7 0.0 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5491) Porin_4 PF13609.6 EAY02371.1 - 0.00033 20.5 3.6 0.0085 15.9 2.0 2.1 1 1 1 2 2 2 2 Gram-negative porin OMP_b-brl PF13505.6 EAY02371.1 - 0.52 10.4 11.4 2.7 8.1 11.4 2.2 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain zf-C2H2_2 PF12756.7 EAY02372.1 - 1.7e-32 111.7 15.8 3.7e-20 72.2 0.2 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 EAY02372.1 - 0.0041 15.7 1.2 0.82 8.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 EAY02372.1 - 0.0067 16.7 0.1 0.0067 16.7 0.1 4.5 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 EAY02372.1 - 0.053 13.6 6.6 0.7 9.9 0.4 3.1 3 0 0 3 3 3 0 CpXC protein zf-met PF12874.7 EAY02372.1 - 0.069 13.6 0.2 0.069 13.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAY02372.1 - 0.83 10.7 30.1 1.1 10.3 0.4 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger DUF2256 PF10013.9 EAY02372.1 - 1.2 9.4 3.6 21 5.3 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) BIR PF00653.21 EAY02372.1 - 4.3 8.1 14.4 4 8.2 0.0 4.8 4 1 1 5 5 5 0 Inhibitor of Apoptosis domain Pkinase PF00069.25 EAY02373.1 - 7.6e-54 182.8 0.0 9.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAY02373.1 - 3.3e-34 118.3 0.0 4.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAY02373.1 - 9.3e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAY02373.1 - 0.00073 19.5 0.0 0.42 10.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EAY02373.1 - 0.0055 16.4 0.7 0.21 11.2 0.0 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EAY02373.1 - 0.0057 15.7 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAY02373.1 - 0.013 14.3 0.0 0.025 13.3 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pestivirus_E2 PF16329.5 EAY02373.1 - 0.059 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 Rhodanese PF00581.20 EAY02375.1 - 1.4e-10 41.7 0.0 1.6e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TrmB PF01978.19 EAY02376.1 - 0.039 13.8 0.1 3.3 7.7 0.0 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB VPS9 PF02204.18 EAY02376.1 - 0.12 12.6 0.3 0.28 11.4 0.2 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Lactamase_B_2 PF12706.7 EAY02377.1 - 2.1e-23 82.9 0.0 2.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAY02377.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LRR_5 PF13306.6 EAY02378.1 - 7.6e-31 106.7 22.1 1.9e-21 76.4 8.6 2.3 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02378.1 - 1.1e-06 28.2 0.1 0.0055 16.4 0.2 2.9 2 0 0 2 2 2 2 Leucine rich repeat BclA_C PF18573.1 EAY02378.1 - 0.0064 16.4 2.0 0.019 14.9 2.0 1.7 1 1 0 1 1 1 1 BclA C-terminal domain Peptidase_M8 PF01457.16 EAY02379.1 - 3.1e-15 55.9 0.0 4.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin S1FA PF04689.13 EAY02379.1 - 0.035 14.2 0.7 0.1 12.7 0.7 1.8 1 0 0 1 1 1 0 DNA binding protein S1FA Ank_5 PF13857.6 EAY02380.1 - 0.00017 21.8 0.7 0.086 13.2 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY02380.1 - 0.00027 21.4 1.4 0.0018 18.8 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02380.1 - 0.00031 21.3 1.8 0.0004 20.9 1.8 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02380.1 - 0.0018 18.6 1.0 1.2 9.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAY02380.1 - 0.16 12.6 1.0 1.8 9.4 0.1 2.4 3 0 0 3 3 3 0 Ankyrin repeat DUF3481 PF11980.8 EAY02381.1 - 0.097 12.4 0.8 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Shisa PF13908.6 EAY02381.1 - 0.15 12.3 1.8 0.25 11.6 1.8 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3149 PF11346.8 EAY02381.1 - 0.17 11.5 2.7 0.31 10.7 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF3060 PF11259.8 EAY02381.1 - 0.21 11.3 7.4 0.047 13.4 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Insulin_TMD PF17870.1 EAY02381.1 - 0.37 10.9 6.2 0.8 9.8 6.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 EAY02381.1 - 0.57 11.1 2.3 1.5 9.8 2.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 EAY02381.1 - 1.6 8.0 7.6 4.6 6.5 7.6 1.6 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Sigma_reg_N PF13800.6 EAY02381.1 - 6.2 7.2 6.1 21 5.5 0.7 3.6 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Glyco_transf_24 PF18404.1 EAY02382.1 - 3.6e-136 452.9 2.7 7.8e-136 451.7 2.7 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EAY02382.1 - 7.9e-18 65.3 7.3 6.3e-17 62.4 0.6 3.4 2 1 1 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAY02382.1 - 6.3e-08 32.5 0.7 6.3e-08 32.5 0.7 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Thioredoxin_13 PF18401.1 EAY02382.1 - 0.00024 21.0 0.2 0.00098 19.1 0.2 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EAY02382.1 - 0.0031 17.6 0.1 0.015 15.4 0.1 2.1 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Inhibitor_I9 PF05922.16 EAY02382.1 - 0.029 15.0 1.6 13 6.5 0.4 3.7 3 0 0 3 3 3 0 Peptidase inhibitor I9 Spore_III_AB PF09548.10 EAY02382.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PRIMA1 PF16101.5 EAY02383.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rap_GAP PF02145.15 EAY02384.1 - 2.5e-37 128.2 0.2 8.5e-37 126.5 0.2 1.9 1 0 0 1 1 1 1 Rap/ran-GAP RWD PF05773.22 EAY02384.1 - 0.11 12.7 0.6 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 RWD domain Mnd1 PF03962.15 EAY02385.1 - 0.042 14.1 0.3 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Mnd1 HTH domain FAD_binding_9 PF08021.11 EAY02385.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ScsC_N PF18312.1 EAY02385.1 - 0.74 9.7 4.7 1.5 8.7 0.1 2.9 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain CAP_N PF01213.19 EAY02386.1 - 0.068 12.7 14.6 0.018 14.6 10.5 1.8 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4522 PF15022.6 EAY02386.1 - 0.081 13.2 0.7 0.14 12.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) PRIMA1 PF16101.5 EAY02386.1 - 0.19 11.8 8.6 0.43 10.6 8.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SMN PF06003.12 EAY02386.1 - 0.48 9.6 6.3 0.76 9.0 6.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) US30 PF17624.2 EAY02386.1 - 0.53 9.3 1.8 0.67 9.0 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function Mito_fiss_reg PF05308.11 EAY02386.1 - 1.1 9.3 15.5 0.52 10.4 13.0 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator Glyco_hydro_38N PF01074.22 EAY02387.1 - 5e-55 186.9 0.0 5e-55 186.9 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EAY02387.1 - 7.5e-29 101.3 3.8 3.1e-21 76.5 3.7 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EAY02387.1 - 7.1e-19 67.8 0.8 1.9e-18 66.4 0.8 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EAY02387.1 - 1.6e-08 34.5 0.0 1.6e-08 34.5 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Thioredoxin PF00085.20 EAY02388.1 - 5.4e-10 39.2 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 EAY02388.1 - 0.0005 20.0 0.7 0.0022 18.0 0.5 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAY02388.1 - 0.049 14.0 1.2 0.44 10.9 0.5 2.9 2 2 1 3 3 3 0 Thioredoxin-like WXG100 PF06013.12 EAY02389.1 - 6.9e-05 23.0 4.3 6.9e-05 23.0 4.3 18.9 13 6 3 19 19 19 7 Proteins of 100 residues with WXG Rootletin PF15035.6 EAY02389.1 - 0.006 16.6 24.3 0.006 16.6 24.3 16.2 1 1 13 14 14 14 1 Ciliary rootlet component, centrosome cohesion LRR_5 PF13306.6 EAY02390.1 - 1.1e-60 203.2 69.2 3.8e-26 91.6 9.8 4.5 1 1 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02390.1 - 5.2e-13 48.5 22.5 0.058 13.2 0.0 10.8 4 4 6 11 11 11 7 Leucine rich repeat LRR_2 PF07723.13 EAY02390.1 - 0.18 12.5 4.3 14 6.6 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat KilA-N PF04383.13 EAY02391.1 - 3.2e-32 110.7 0.7 6.4e-32 109.7 0.1 1.8 2 0 0 2 2 2 1 KilA-N domain PSP PF04046.16 EAY02392.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP XRN1_D1 PF18332.1 EAY02393.1 - 0.13 12.1 0.2 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain XRN_N PF03159.18 EAY02394.1 - 1.4e-34 119.6 0.0 1.1e-23 83.9 0.0 2.1 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus DUF3839 PF12943.7 EAY02395.1 - 8e-153 506.8 15.4 9.8e-153 506.5 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Rx_N PF18052.1 EAY02395.1 - 0.032 14.5 5.2 0.17 12.2 0.1 3.4 2 2 1 3 3 3 0 Rx N-terminal domain DUF2408 PF10303.9 EAY02395.1 - 0.14 12.7 3.5 1.5 9.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NTP_transf_6 PF06042.11 EAY02395.1 - 0.16 11.8 1.9 0.33 10.8 0.3 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase KELK PF15796.5 EAY02395.1 - 0.44 11.0 6.2 4.2 7.9 0.3 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1493 PF07377.12 EAY02396.1 - 0.067 13.7 0.5 0.15 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY02397.1 - 0.063 13.9 5.5 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY02398.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP POP1 PF06978.11 EAY02399.1 - 4.4e-32 111.7 14.7 3.4e-18 66.4 4.5 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EAY02399.1 - 7e-20 71.2 1.3 1.5e-19 70.1 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain Tfb5 PF06331.12 EAY02399.1 - 0.037 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF5475 PF17569.2 EAY02400.1 - 0.035 14.4 0.1 0.34 11.3 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5475) NPV_P10 PF05531.12 EAY02401.1 - 0.0077 16.7 15.5 1.2 9.7 0.1 4.4 2 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein DASH_Dad4 PF08650.10 EAY02401.1 - 0.013 15.5 0.9 0.013 15.5 0.9 3.1 3 1 0 3 3 3 0 DASH complex subunit Dad4 HsbA PF12296.8 EAY02401.1 - 0.032 14.7 0.6 1.8 9.0 0.1 2.9 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Cep57_CLD_2 PF14197.6 EAY02401.1 - 0.037 14.1 0.5 0.037 14.1 0.5 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF3450 PF11932.8 EAY02401.1 - 0.061 12.6 8.5 0.042 13.1 2.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Closter_coat PF01785.17 EAY02401.1 - 0.099 11.9 1.6 0.24 10.7 1.6 1.6 1 0 0 1 1 1 0 Closterovirus coat protein LPP PF04728.13 EAY02401.1 - 0.19 12.1 0.2 0.19 12.1 0.2 3.9 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DivIC PF04977.15 EAY02401.1 - 1 9.2 9.3 1.3 8.8 1.6 3.2 2 1 0 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EAY02401.1 - 1.1 9.5 14.8 0.68 10.1 3.3 3.4 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.17 EAY02401.1 - 1.3 9.0 12.0 0.28 11.1 0.6 3.8 4 0 0 4 4 4 0 Prefoldin subunit Vac_Fusion PF02346.16 EAY02401.1 - 2 8.1 6.0 3.9 7.2 0.1 3.6 3 1 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 KELK PF15796.5 EAY02401.1 - 2.3 8.7 8.5 0.28 11.7 2.4 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2203 PF09969.9 EAY02401.1 - 2.4 8.9 8.8 46 4.8 4.2 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 EAY02401.1 - 2.5 8.6 16.9 8.8 6.9 0.0 3.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EAY02401.1 - 3 8.2 12.3 0.57 10.6 6.5 2.4 2 1 0 2 2 2 0 Fez1 DUF5082 PF16888.5 EAY02401.1 - 3.2 8.0 19.6 1.8e+02 2.4 10.2 4.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 EAY02401.1 - 5.1 7.5 19.2 1.4 9.2 0.1 4.4 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PH PF00169.29 EAY02402.1 - 5.9e-06 26.8 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 PH domain Sec7 PF01369.20 EAY02402.1 - 0.002 17.9 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain ADK PF00406.22 EAY02403.1 - 3.3e-05 24.0 0.2 0.016 15.3 0.0 3.6 3 1 0 3 3 3 1 Adenylate kinase YHS PF04945.13 EAY02403.1 - 0.0012 18.8 4.6 0.69 10.1 0.1 4.2 4 0 0 4 4 4 1 YHS domain AAA_18 PF13238.6 EAY02403.1 - 0.015 15.8 0.1 8.2 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain FAP206 PF12018.8 EAY02403.1 - 0.057 12.9 16.7 3.1 7.2 0.1 6.2 6 1 0 7 7 7 0 Domain of unknown function RP-C_C PF11800.8 EAY02403.1 - 0.96 9.5 6.8 6.3 6.8 7.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region TFB6 PF17110.5 EAY02403.1 - 3.2 7.5 13.6 0.073 12.8 4.7 2.7 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH PseudoU_synth_1 PF01416.20 EAY02404.1 - 1.1e-25 90.2 0.0 6e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase MPS2 PF17060.5 EAY02405.1 - 0.01 15.2 2.3 0.015 14.6 2.1 1.2 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF5531 PF17671.1 EAY02405.1 - 0.028 14.3 0.7 0.028 14.3 0.7 1.6 1 1 0 2 2 2 0 Family of unknown function (DUF5531) Wtap PF17098.5 EAY02405.1 - 0.097 12.6 6.9 0.91 9.4 6.5 2.2 1 1 1 2 2 2 0 WTAP/Mum2p family bZIP_1 PF00170.21 EAY02405.1 - 0.25 11.4 3.9 0.67 10.1 3.7 1.8 1 1 0 1 1 1 0 bZIP transcription factor ATG16 PF08614.11 EAY02405.1 - 0.96 9.6 13.1 1.2 9.3 13.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TFIIA PF03153.13 EAY02405.1 - 7 6.5 24.0 8.5 6.2 24.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TH1 PF04858.13 EAY02406.1 - 3.7e-06 25.9 0.1 2.2e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 TH1 protein DUF4229 PF14012.6 EAY02406.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) C2 PF00168.30 EAY02407.1 - 4.2e-17 62.3 0.0 9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF2547 PF10818.8 EAY02407.1 - 0.11 13.4 4.1 0.17 12.8 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Metallophos PF00149.28 EAY02409.1 - 0.00046 20.7 0.0 0.00085 19.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF563 PF04577.14 EAY02410.1 - 2.2e-24 86.8 0.0 2.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Orexin_rec2 PF03827.13 EAY02410.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Orexin receptor type 2 PROCN PF08083.11 EAY02411.1 - 1.4e-213 709.0 8.9 2.3e-213 708.3 8.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EAY02411.1 - 2.1e-108 361.3 0.3 4.2e-108 360.3 0.3 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EAY02411.1 - 8.6e-84 279.3 2.1 2.2e-83 277.9 2.1 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EAY02411.1 - 5.6e-73 243.9 0.3 1.5e-72 242.5 0.3 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EAY02411.1 - 2e-65 218.9 0.1 4.4e-65 217.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EAY02411.1 - 7.9e-41 138.3 0.5 1.8e-40 137.1 0.5 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EAY02411.1 - 9.3e-29 99.8 0.1 2.5e-28 98.5 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain Gly_rich PF12810.7 EAY02412.1 - 2.5e-19 70.2 28.3 2.9e-19 70.0 28.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Tubulin PF00091.25 EAY02413.1 - 5.9e-68 229.0 0.0 8.4e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAY02413.1 - 2.4e-50 169.9 0.0 3.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAY02413.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 EAY02413.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Fringe PF02434.16 EAY02414.1 - 2.5e-09 37.0 0.0 3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Ank_2 PF12796.7 EAY02415.1 - 9.6e-14 51.7 7.2 2.2e-07 31.3 0.9 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAY02415.1 - 4.6e-09 36.6 0.3 1.2e-08 35.3 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02415.1 - 2e-06 27.7 2.2 0.023 15.2 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAY02415.1 - 0.00013 22.2 0.1 0.021 15.1 0.1 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAY02415.1 - 0.0023 18.3 0.8 0.48 11.0 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat WD40 PF00400.32 EAY02416.1 - 7.9e-21 74.0 4.9 2.6e-08 34.4 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EAY02416.1 - 1.5e-11 44.6 0.8 2.5e-11 43.9 0.8 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EAY02416.1 - 2.7e-07 30.8 0.1 0.0041 17.4 0.0 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EAY02416.1 - 0.023 13.0 0.0 0.037 12.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz McyA_C PF12593.8 EAY02416.1 - 0.16 11.8 0.2 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Microcystin synthetase C terminal RP-C_C PF11800.8 EAY02417.1 - 0.083 13.0 4.6 0.23 11.5 4.6 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 EAY02417.1 - 1.5 7.5 10.4 2.5 6.8 10.4 1.3 1 0 0 1 1 1 0 Presenilin LRR_5 PF13306.6 EAY02421.1 - 4.1e-40 136.7 19.0 4.9e-22 78.3 8.9 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02421.1 - 3.2e-11 42.8 0.1 5.6e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 EAY02422.1 - 9.7e-69 229.2 41.1 1.3e-26 93.0 2.3 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02422.1 - 7.7e-10 38.4 1.2 0.26 11.1 0.1 5.8 5 1 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EAY02422.1 - 0.027 14.9 8.0 3.8 8.1 0.2 5.7 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) KilA-N PF04383.13 EAY02423.1 - 3.7e-38 129.8 0.2 8.1e-38 128.7 0.2 1.6 1 0 0 1 1 1 1 KilA-N domain Parathyroid PF01279.17 EAY02423.1 - 0.0074 16.9 0.3 0.034 14.8 0.0 1.9 2 0 0 2 2 2 1 Parathyroid hormone family T5orf172 PF10544.9 EAY02424.1 - 3.2e-07 30.8 0.1 7.7e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain KilA-N PF04383.13 EAY02424.1 - 0.024 14.5 2.7 0.11 12.4 1.2 2.6 2 1 0 2 2 2 0 KilA-N domain FRG PF08867.11 EAY02424.1 - 0.065 14.2 0.2 0.96 10.4 0.0 2.2 2 0 0 2 2 2 0 FRG domain DUF3839 PF12943.7 EAY02425.1 - 5.4e-148 491.0 14.8 6.6e-148 490.7 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) KELK PF15796.5 EAY02425.1 - 0.78 10.2 7.5 2.1 8.8 0.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4116 PF13475.6 EAY02426.1 - 0.023 14.4 2.1 0.036 13.8 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) F420_ligase PF01996.16 EAY02426.1 - 0.061 12.7 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase HSP70 PF00012.20 EAY02426.1 - 0.54 8.4 8.6 0.7 8.0 8.6 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF1493 PF07377.12 EAY02427.1 - 0.029 14.8 0.7 0.063 13.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) TMP PF05017.14 EAY02428.1 - 0.065 13.8 5.6 11 7.2 0.2 3.4 3 1 0 3 3 3 0 TMP repeat PSP PF04046.16 EAY02429.1 - 0.071 13.0 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PSP TPR_1 PF00515.28 EAY02430.1 - 1.1e-14 53.5 5.7 4.7e-05 23.0 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAY02430.1 - 8.6e-09 34.9 10.0 0.0018 18.2 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAY02430.1 - 6.2e-07 29.0 2.5 0.0018 17.9 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 EAY02430.1 - 0.00016 21.9 0.9 0.0027 18.0 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAY02430.1 - 0.00067 20.1 0.1 0.094 13.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAY02430.1 - 0.0012 18.9 11.3 0.97 9.8 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat CDPS PF16715.5 EAY02430.1 - 0.0022 17.7 2.5 0.067 12.8 0.4 2.1 2 0 0 2 2 2 1 Cyclodipeptide synthase TPR_16 PF13432.6 EAY02430.1 - 0.0052 17.4 0.1 0.64 10.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAY02430.1 - 0.01 15.9 2.5 3.8 7.7 0.1 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EAY02430.1 - 0.044 13.8 0.7 0.044 13.8 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2951 PF11166.8 EAY02430.1 - 0.068 13.4 0.7 0.068 13.4 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) TPR_6 PF13174.6 EAY02430.1 - 0.086 13.5 2.6 3.7 8.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAY02430.1 - 0.086 12.9 2.0 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltrn_RNA_4 PF09936.9 EAY02430.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase TPR_14 PF13428.6 EAY02430.1 - 0.12 13.3 0.1 15 6.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EAY02430.1 - 0.13 12.4 7.6 3.2 7.9 1.9 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EAY02430.1 - 0.14 12.6 4.8 0.59 10.6 0.2 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2524 PF10732.9 EAY02430.1 - 4.7 7.6 8.5 7.5 6.9 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Ras PF00071.22 EAY02431.1 - 1.9e-33 115.3 0.0 2.4e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY02431.1 - 5e-27 94.5 0.0 3.6e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY02431.1 - 2.5e-11 43.3 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY02431.1 - 6.5e-07 28.9 0.0 8.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAY02431.1 - 7.4e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAY02431.1 - 2.8e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAY02431.1 - 0.0011 18.7 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAY02431.1 - 0.0028 17.2 0.0 0.11 12.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EAY02431.1 - 0.029 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 EAY02431.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAY02431.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin family NifU PF01106.17 EAY02432.1 - 1.1e-22 80.0 0.6 1.3e-22 79.7 0.6 1.1 1 0 0 1 1 1 1 NifU-like domain HSP70 PF00012.20 EAY02433.1 - 1.7e-251 835.7 3.4 1.9e-251 835.5 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAY02433.1 - 1.5e-15 56.8 0.0 3.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EAY02433.1 - 0.00057 19.7 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EAY02433.1 - 0.0049 17.3 0.4 8 6.9 0.0 3.5 3 2 0 3 3 3 1 Cell division protein FtsA StbA PF06406.11 EAY02433.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 EAY02433.1 - 0.051 12.8 0.1 0.1 11.8 0.1 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase Terminase_2 PF03592.16 EAY02434.1 - 0.25 11.8 2.3 0.68 10.4 0.2 2.2 2 0 0 2 2 2 0 Terminase small subunit P2 PF07194.11 EAY02434.1 - 1.1 9.3 6.2 2 8.5 0.5 3.2 3 0 0 3 3 3 0 P2 response regulator binding domain Ribosomal_L18_c PF14204.6 EAY02434.1 - 4.1 8.4 10.4 2.5 9.1 1.1 3.6 3 1 0 3 3 3 0 Ribosomal L18 C-terminal region LCM PF04072.14 EAY02435.1 - 4.3e-20 72.4 0.0 8.1e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Pkinase_Tyr PF07714.17 EAY02436.1 - 2.5e-52 177.8 0.0 4.3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAY02436.1 - 1.4e-51 175.4 0.0 2.5e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAY02436.1 - 9.8e-05 22.4 0.0 0.0007 19.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAY02436.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAY02436.1 - 0.055 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF563 PF04577.14 EAY02437.1 - 8.8e-33 114.2 1.7 1.3e-32 113.7 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ribosomal_L5_C PF00673.21 EAY02438.1 - 3.5e-17 62.3 0.0 5.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAY02438.1 - 1e-09 38.5 0.3 1.7e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 MFS_1 PF07690.16 EAY02439.1 - 1.8e-36 125.8 58.4 5.5e-31 107.8 38.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb1_3 PF04983.18 EAY02440.1 - 0.0095 15.9 0.5 0.052 13.5 0.5 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RTP1_C1 PF10363.9 EAY02440.1 - 0.076 13.2 0.3 8.5 6.6 0.0 3.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Gly_rich PF12810.7 EAY02441.1 - 3.2e-44 151.7 31.3 3.7e-44 151.5 31.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY02442.1 - 6.2e-37 127.8 20.3 7.9e-37 127.5 20.3 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY02443.1 - 4.7e-32 111.8 24.6 5.6e-32 111.6 24.6 1.0 1 0 0 1 1 1 1 Glycine rich protein Gly_rich PF12810.7 EAY02444.1 - 1.3e-50 172.6 26.6 1.5e-50 172.4 26.6 1.0 1 0 0 1 1 1 1 Glycine rich protein DHR-2 PF06920.13 EAY02445.1 - 1.5e-108 363.8 0.2 3.2e-108 362.7 0.2 1.6 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EAY02445.1 - 3.1e-17 63.0 1.3 5.9e-17 62.1 0.4 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SNF2_N PF00176.23 EAY02446.1 - 2.3e-44 151.6 0.0 1.1e-43 149.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAY02446.1 - 4.5e-15 56.0 0.0 1.7e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 EAY02446.1 - 0.0042 17.5 0.0 3.7 8.0 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EAY02446.1 - 0.0087 16.2 0.0 9.6 6.8 0.0 3.4 2 0 0 2 2 2 2 HEAT repeat HpaB_N PF11794.8 EAY02446.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cas6b_C PF17262.2 EAY02446.1 - 0.12 12.4 0.2 3.7 7.7 0.0 3.3 3 0 0 3 3 3 0 Cas6b C-terminal domain Ank_4 PF13637.6 EAY02448.1 - 2e-45 152.6 11.7 1.5e-12 47.7 0.3 8.7 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAY02448.1 - 2.1e-44 150.0 20.3 3.6e-17 62.7 1.9 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAY02448.1 - 4.3e-39 131.3 5.4 4.4e-09 36.4 0.2 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAY02448.1 - 4.9e-35 119.1 12.7 3.9e-10 39.8 0.2 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02448.1 - 8.6e-33 108.7 6.6 4.3e-06 26.6 0.1 9.0 10 0 0 10 10 10 5 Ankyrin repeat DUF3447 PF11929.8 EAY02448.1 - 5.1e-32 109.6 4.3 5.1e-32 109.6 4.3 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EAY02448.1 - 0.023 14.9 0.6 10 6.5 0.1 3.8 1 1 1 3 3 3 0 Ribosomal protein S6 HEM4 PF02602.15 EAY02448.1 - 0.16 11.3 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD RL PF17797.1 EAY02448.1 - 9.2 6.3 9.2 4.3 7.4 0.1 4.5 5 1 0 5 5 5 0 RL domain Herpes_IE2_3 PF03361.14 EAY02450.1 - 0.0098 15.8 1.0 0.32 10.9 0.2 2.2 2 0 0 2 2 2 1 Herpes virus intermediate/early protein 2/3 PPP5 PF08321.12 EAY02450.1 - 0.012 15.8 3.8 1 9.7 0.8 2.7 2 0 0 2 2 2 0 PPP5 TPR repeat region Toxin_R_bind_C PF07951.12 EAY02450.1 - 0.027 14.1 3.9 0.12 12.0 0.3 2.6 2 1 1 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding LRR_5 PF13306.6 EAY02451.1 - 3.3e-101 334.2 60.1 8.5e-25 87.2 3.0 6.2 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EAY02451.1 - 2.2e-26 91.4 0.7 1.9e-05 24.3 0.3 8.4 7 1 2 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 EAY02451.1 - 0.00097 19.5 11.7 2.1 8.9 0.5 6.6 4 2 3 8 8 8 2 Leucine Rich repeats (2 copies) Baculo_LEF5 PF04838.12 EAY02452.1 - 0.0052 16.8 1.7 2 8.4 0.1 2.3 1 1 0 2 2 2 2 Baculoviridae late expression factor 5 DUF3447 PF11929.8 EAY02452.1 - 0.006 16.5 1.9 0.041 13.8 0.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) DUF3447 PF11929.8 EAY02453.1 - 2.8e-09 36.8 0.3 2.8e-09 36.8 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) DUF4408 PF14364.6 EAY02454.1 - 0.021 14.6 0.5 0.075 12.8 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) FNIP PF05725.12 EAY02454.1 - 6.8 6.9 7.6 8 6.7 0.3 3.5 3 0 0 3 3 3 0 FNIP Repeat Hus1 PF04005.12 EAY02456.1 - 1e-60 205.4 1.9 2e-60 204.4 1.9 1.4 1 1 0 1 1 1 1 Hus1-like protein Phage_TAC_1 PF06222.11 EAY02456.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF4223 PF13978.6 EAY02456.1 - 0.07 13.1 0.3 9.6 6.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) PG_binding_2 PF08823.11 EAY02457.1 - 0.022 15.1 0.1 0.45 10.9 0.2 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF87 PF01935.17 EAY02457.1 - 0.12 12.5 0.6 0.34 10.9 0.6 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain GPS2_interact PF15784.5 EAY02458.1 - 0.026 14.9 1.5 0.035 14.5 1.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DDR PF08841.10 EAY02458.1 - 0.099 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF2939 PF11159.8 EAY02459.1 - 0.013 15.9 0.4 0.017 15.6 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) TERB2 PF15101.6 EAY02459.1 - 1.5 8.8 5.8 1.6 8.7 5.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Membralin PF09746.9 EAY02459.1 - 1.7 7.6 3.0 1.8 7.5 3.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_32 PF13565.6 EAY02459.1 - 1.7 9.3 6.2 3.9 8.2 6.2 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PapD_N PF00345.20 EAY02460.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DNA_pol_B_2 PF03175.13 EAY02461.1 - 2.2e-26 92.8 14.0 1.2e-25 90.3 14.0 2.0 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Amidase02_C PF12123.8 EAY02463.1 - 0.073 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF4107 PF13389.6 EAY02464.1 - 3.2e-71 238.7 2.9 4.5e-71 238.3 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Ras PF00071.22 EAY02466.1 - 8.5e-50 168.5 0.5 1.1e-49 168.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAY02466.1 - 8.5e-34 116.3 0.4 1.3e-33 115.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAY02466.1 - 1.8e-14 53.6 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAY02466.1 - 0.00027 20.4 0.1 0.00037 19.9 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAY02466.1 - 0.00037 20.4 0.1 0.51 10.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAY02466.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAY02466.1 - 0.0013 18.5 0.2 0.0025 17.6 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAY02466.1 - 0.0016 18.0 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region SRPRB PF09439.10 EAY02466.1 - 0.0018 17.7 0.2 0.0049 16.3 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EAY02466.1 - 0.0031 16.9 0.0 0.011 15.2 0.0 1.8 3 0 0 3 3 3 1 Bacterial TniB protein ATP_bind_1 PF03029.17 EAY02466.1 - 0.0055 16.5 0.1 0.099 12.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EAY02466.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 EAY02466.1 - 0.054 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain Peptidase_C14 PF00656.22 EAY02467.1 - 7.7e-15 55.5 0.2 2.2e-14 54.0 0.2 1.6 1 1 0 1 1 1 1 Caspase domain DUF2231 PF09990.9 EAY02468.1 - 0.097 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Serglycin PF04360.12 EAY02468.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Serglycin HARP PF07443.13 EAY02469.1 - 0.0035 16.9 1.9 0.0051 16.4 0.4 1.9 2 0 0 2 2 2 1 HepA-related protein (HARP) DUF4570 PF15134.6 EAY02469.1 - 0.016 15.2 1.5 0.027 14.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SKA2 PF16740.5 EAY02469.1 - 0.019 14.7 1.2 0.032 14.0 1.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Ank_2 PF12796.7 EAY02470.1 - 1.7e-67 224.0 19.7 5e-17 62.3 0.4 8.1 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAY02470.1 - 1.1e-60 200.8 9.1 1.8e-10 40.9 0.0 10.8 5 3 7 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAY02470.1 - 5.6e-59 195.8 10.7 9.4e-12 45.2 0.2 10.6 6 2 6 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAY02470.1 - 2.6e-54 174.8 13.6 0.00013 22.1 0.1 14.5 15 0 0 15 15 15 10 Ankyrin repeat Ank PF00023.30 EAY02470.1 - 8.2e-41 136.7 13.3 0.00033 21.0 0.1 13.3 13 1 1 14 14 14 10 Ankyrin repeat PUB_1 PF18486.1 EAY02470.1 - 0.0054 16.6 0.2 2.9 7.8 0.1 2.6 2 0 0 2 2 2 2 PNGase/UBA- or UBX-containing domain DUF3447 PF11929.8 EAY02470.1 - 0.0088 16.0 8.3 0.067 13.1 0.0 5.2 4 1 1 5 5 5